LOCUS       DAEORM030000001       199179 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.001, whole genome shotgun sequence.
ACCESSION   DAEORM030000001 DAEORM030000000
VERSION     DAEORM030000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 199179)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 199179)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 199179)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..199179
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.001"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            198..338
                     /locus_tag="KRH23_000001"
     CDS             198..338
                     /locus_tag="KRH23_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5223301.1"
                     /translation="MGIIESASKLAEMVHLLAVEKGITDIEAWDEAVKEYSKIYEERR
                     NE"
     gene            complement(513..833)
                     /locus_tag="KRH23_000002"
     CDS             complement(513..833)
                     /locus_tag="KRH23_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HHS5223302.1"
                     /translation="MKLKTISLPELNNLDPTLESTFIKMGEEQGELAECIGKFRNLSG
                     ENNDLDEVDIIKKTAKELMDVAQTCVTMMFKLEEQYGINLDEIRKEHIKKLEKRGYIK
                     NMDK"
     gene            complement(953..1690)
                     /locus_tag="KRH23_000003"
     CDS             complement(953..1690)
                     /locus_tag="KRH23_000003"
                     /EC_number="2.3.1.286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0034979 - NAD-dependent protein lysine
                     deacetylase activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HHS5223303.1"
                     /translation="MDANSLKDLIANHNNIVFFGGAGVSTESNIPDFRSSTGLFSQKL
                     NKQFTAEQLVSHTFFVRYPEEFFEFYKDKLIYPNAKPNNAHIALAKLEEMGKLKAVIT
                     QNIDGLHQMAGSKNVLELHGSVHRNYCTKCGKFFDLESMLNLGGNIPYCDNCGSIVKP
                     DVVLYEEALDSDVITKTISAISNADLLIIGGTSLAVYPAASFIDYYKGDYIALINKAN
                     TVYDKSASLVINKPIGEVLYEAVLRQI"
     gene            1905..3728
                     /gene="acd"
                     /locus_tag="KRH23_000004"
     CDS             1905..3728
                     /gene="acd"
                     /locus_tag="KRH23_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosaminidase"
                     /protein_id="HHS5223304.1"
                     /translation="MKKKAALATLAMLPLGVVNAHADGDIGIVTINYLNVRNEPTAES
                     SIAFVAKKDDKVLIKDSSNGWYKIKAESGQEGWASSKYIAKSNSDSLRTSTNKEKQVI
                     SNSLNMRNGAGTSYRVITVLKKGQKVEVISESNGWSKIKYDGRLGYVSSSYLGDVSNS
                     TNKSKTKQVNTTSLNVRSGPNTSYGLLGKLPKGSKVEVISESNGWSKIKYNGKDAYVS
                     SMYLSDVSQSNSDNSSQSNDKKNTDKVVNTASLNVRSGPGSTYSKLGKVYKGSKVTVL
                     SESSGWAKINFNNKEAFVVGNYLSTSADTSNNNSNSNSDSSSNSNGNNSSSSGQVNGM
                     SGISGAKIDYKSLSYTLESHISKQVEKAASGGNVIAPSNRKSTPSPEFSTFSAQRTSS
                     FVNASSSDIEYYLNPKNFTNTTKGMMQFLKINSYRDGISESSLNSYLNGLSSSVFKNQ
                     GAAFINAAKKYNIDVVYLVSHAMWETAYGKSTLAQGQTLTSYKGQPLSKPVKVYNFFG
                     IGAIDKSANVSGAEAAYSNGWTSVEATIDGSAKWISQNYVNSSKYNQNTIYKMKWNYD
                     YTWHQYATDVNWANGISGIMENLIGLYGGGSSLVFEVPQYK"
     gene            3943..8241
                     /locus_tag="KRH23_000005"
     CDS             3943..8241
                     /locus_tag="KRH23_000005"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HHS5223305.1"
                     /translation="MESIKEYLDKLEINNSGLGKQLKEVYINRVVYFKEDKIVYFYLT
                     SKDIVSHELLDKFKEELMYKLDYFKDMRMKIRFTGLERKSNKDVIKKYWNNILYILKY
                     LCPSIAGWYKQVEFLCLEEELKIKLPKGIFYERLMKKNVTYVLKTVLSEELGLDLNIT
                     IEKAVDEKVNKERLIRINDREMEEKIRALEIGKVNNCEENEEESYVIKSDVDENLIYG
                     DNANAMIENIVELNASSGTVAVVGDIFDVDTKELKNGKILMIASITDYTSSISCKLFL
                     TDTNKDGVLENVKKGAYLKIKGDIVYDTYQREISMMISGIRKETRIEREDKSEEKRVE
                     LHAHTQMSSMDAICSVKKLVERAAKWGHSAIAITDHGVVQGFPDAMNAGKSNNIKILY
                     GVEGYLVEDDSLIIEDANDKELSQTFVVFDIETTGFSNTNDKITEIGAVKIENFKIVD
                     RFSELINPEKDISYKIQELTGITNELIKDKPTIEEVLPKFMEFVGDSVLVAHNAEFDT
                     GFISQKCREQGLLYNNKKVDTLMLARVMLPNLKRHRLNVVAKELGIPLLNHHRAVDDA
                     EATALIFNKFLQMLTEKGAKTLSDVNNILGKIDYTKLSTNHITLIAKNSIGIKNLYKI
                     ISDAHVNHFFRAPRILRSVLNEYKEGLIIGSACEAGVVFQAVKKNVSDEEMKKIIDLY
                     DYIEVMPIDNNRFMIDKGEVKDEEELRELNRKLIDTAKKFDKIPVATGDVHFLDKHEA
                     VLRKVLKYSQGFKVDEEETYLHFRTTDEMLEEFSYLGEELAYEVVVENSNLIADMVED
                     IKPIPDDTYPPIIEGSDVELREMCYKKAKRIYGDPIPEIVQKRLDRELNSIISNGYAV
                     MYIIAQKLVAKSLSDGYLVGSRGSVGSSFAATMSDITEVNPLPAHYICENEDCKYSFF
                     YEIGEWGSGVDLPDKDCPKCGRKLAKNGHDIPFEVFLGFEGDKEPDIDLNFSGNYQPT
                     IHKYTEELFGEGYVYRAGTIGTVAEKTAFGYARKYVEENNISVPNAEVLRLSNGCTGV
                     KRTSGQHPGGVMVIPDYKDVYDFTPIQYPANDTSCGVITTHFDYHSISGRILKLDILG
                     HDGPTIIRMLEDMTGINITEIPLDDKETMSLFTSTEALGVTPEEINCPIGCLAVPEFG
                     TKFVRQMLLDTKPTTFAELVRISGLSHGTDVWVNNAQDLVREDIVGLKDVISTRDDIM
                     NYLIFKGLPPKMSFTIMESVRKGKGLKPEHIEEMKKNNVPEWYIGSCKKIKYMFPKAH
                     AVAYVMTSFRIAYCKVHYPEAFYATYFTTKVEDFDADLIVKGLDAIKSKINEIESLGN
                     DATTKEKGMLTVLEVALEMYARGIKLLPVDIYKSDATEFIVVGEKTLLPPMAAIQGLG
                     GNAAINIQNERKNGEFISKEDLRKRTKISKTVIETLTNHGSLENMSERNQLSLF"
     gene            8445..8906
                     /gene="rimP"
                     /locus_tag="KRH23_000006"
     CDS             8445..8906
                     /gene="rimP"
                     /locus_tag="KRH23_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000028 - ribosomal small subunit assembly
                     [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0042274 - ribosomal small subunit
                     biogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HHS5223306.1"
                     /translation="MKKNLEATIEEIVTKITDEHGFEMVDVEYVKEAGEYYLRVYIDK
                     EEGISLNECELVSRELSPILDEKDPIKENYFLEVSSPGLDRALKKDRDFVRYQGRDVD
                     LKLYKPLNGCKQFEGELVGLTEDNNIKIIANGKEMEFNRKDVAIVRLAIKF"
     gene            8936..10090
                     /gene="nusA"
                     /locus_tag="KRH23_000007"
     CDS             8936..10090
                     /gene="nusA"
                     /locus_tag="KRH23_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor NusA"
                     /protein_id="HHS5223307.1"
                     /translation="MNHEFMEALDELVVDRGIDKEILIDTIEQALLTAYKKNFGSAQN
                     VRVEFDRDKGDIKVFSQRVVVDESDLYDTFLEIELADAREINPNYELGDIIEHEVTPK
                     NFGRIAAQTAKQVVVQRIREAEREIVYNEFIEKENEIVTGEVARANKNVVYVNLGRIE
                     GIMTQSEQIPFENYKAGQKIKFYILEVKKTNKGPQIVVSRSHPGLVKRLFEEEVPEIY
                     EGIVQIKSVAREAGSRTKMAVRSIDEKIDPIGACVGPKGLRVKNIVDELGDEKIDIIK
                     YSEDPAEFISAALSPSKVVRVDIDEDEKSALVIVPDYQLSLAIGKEGQNARLAAKLTN
                     WKIDIKSESQAEQEMLNLENSKEIEAEDVEAEFIDQEELDTSEDNFSEEE"
     gene            10097..10378
                     /gene="rnpM"
                     /locus_tag="KRH23_000008"
                     /gene_synonym="ylxR"
     CDS             10097..10378
                     /gene="rnpM"
                     /locus_tag="KRH23_000008"
                     /gene_synonym="ylxR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase P modulator RnpM"
                     /protein_id="HHS5223308.1"
                     /translation="MILKKVKKVPQRKCIACQDRDSKKELIRIVKNKEGKIFLDPTGR
                     ANGRGAYVCKSSECLKKAIKSKALNKAFKIDVPDEVYDNLLMELEEYEK"
     gene            10368..10679
                     /locus_tag="KRH23_000009"
     CDS             10368..10679
                     /locus_tag="KRH23_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L7Ae/L30e/S12e/Gadd45 family ribosomal protein"
                     /protein_id="HHS5223309.1"
                     /translation="MKNNKEKVLSFLGLATRAGKIVSGDDSTLLDLKKGKVNLILIAE
                     DASNNTKKLFKDKSTFRNIPYLFFSTKEEIGFAIGKSPRAVVGIKDENFSKKIIELIE
                     I"
     gene            10701..12641
                     /gene="infB"
                     /locus_tag="KRH23_000010"
     CDS             10701..12641
                     /gene="infB"
                     /locus_tag="KRH23_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HHS5223310.1"
                     /translation="MSKTRVYQIAEELNISNEELINKLAELDINVTDKDSVLEGEELE
                     LALEMLGEDLSQENGNVIEIDGKLTVQVLATKLDKSPSEIIMKLMKMGTMATINQEIS
                     FEIAALAAKDYGFELTVAESDDTEALEIEALMEIEEDKEEDLKPRPPVVTVMGHVDHG
                     KTSLLDAIRKTDVISGEAGGITQHIGASEVKINGHKIVFLDTPGHEAFTSMRARGAQV
                     TDIAILVVAADDGIMPQTVEAINHAKAAGVPLIVAINKIDKPGANPDKVKQELADQGL
                     LVEDWGGEVIAVPVSAKKKEGIDTLLEMVLLVAEMEELRANPNKRAVGTVIEAELDKG
                     RGPVATVLVQGGTLTVGDPIVAGVACGKVRAMINAKGKRVKTAGPSTAVEILGLSEVP
                     QGGDQFVEVPTDKIARSVAARRQQIVRDEMLKSTQRLSLDALFSQMSEGSIKDLNIVI
                     KADVQGSVQAVKQSLEKLSNEEVQVKVIHGGVGAVTESDILLAAASNAIIIGFNVRPV
                     PGAESLGEKENVDIRTYTIIYKAIEDIQAAMTGMLDPEYVDEETGKAEIREIYKISGV
                     GTVAGCYVTNGKIFRNCKVRLVRDSIIIHEGELAALKRFKDDVKEVNSGYECGMSFVN
                     YNDIKEGDIVEAYITKEVERKL"
     gene            12684..13064
                     /gene="rbfA"
                     /locus_tag="KRH23_000011"
     CDS             12684..13064
                     /gene="rbfA"
                     /locus_tag="KRH23_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HHS5223311.1"
                     /translation="MASYNRTRRIAEEIRKVVSTMLINGVKDPRITSMVSVTDVEVTN
                     DLRYAYVYVSILGGDEESTLTGLKSAGGYIRREVGKNIKLRYIPEIVFKLDDSIEKGM
                     YMDSLIKRVNEKDAQQNEDENYDE"
     gene            13045..14028
                     /locus_tag="KRH23_000012"
     CDS             13045..14028
                     /locus_tag="KRH23_000012"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HHS5223312.1"
                     /translation="MKIMMNNMDSIINYIYEGDYFIVTSHISPDGDNIGSTLSMYYTL
                     KNLGKNVYYVLDDEAPLNLRFLVEGVKIYKSNEFNMKNYSLIALDCGDKMRICVSDEI
                     KNNASKLICIDHHASNDSYGDLNYVDIDASSTCELVYNLLVRFQQIKDINIINEDIAT
                     CLYTGLVTDTGNFSYSNVHASSFEMAKNLLVLGAQKNTIIQNIYQSNSSDYYKLLGEA
                     LKGLEIFDSKVSSIVLTQDMMNRNNISFNDVDGITTYTRDIKGIEVGILFKEKKQNEI
                     KVSFRSKNYVDVSEIAKLFGGGGHVRAAGCTIRDSIDNAKKMVLEAVLKSI"
     gene            14041..14946
                     /gene="truB"
                     /locus_tag="KRH23_000013"
     CDS             14041..14946
                     /gene="truB"
                     /locus_tag="KRH23_000013"
                     /EC_number="5.4.99.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HHS5223313.1"
                     /translation="MNKIISILKPTGMTSHDVVSRVRKILNIKKVGHTGTLDPDASGV
                     LPICIGKATKVCEVILNKDKSYICELTLGISTDTYDASGEILKKVDDFKFSNEDIERA
                     FDTQRGEINQLPPIYSALKVNGKRMCDLVRSGRQSEITLKTRRVNIKDIKILSIKGNK
                     VMFYVECSKGTYVRSICHDIGEYLGCGAHMSFLNRTSSGKFDLDNSITLEELELFYEN
                     KTLDKYLYDIDYVLDSFNYVVLNPNAIKYYSNGGSIDDKRFLKNNFDKDDEFVRVYST
                     DNFLGLGKLSKHNNTISVKSDKMFI"
     gene            15077..16006
                     /locus_tag="KRH23_000014"
     CDS             15077..16006
                     /locus_tag="KRH23_000014"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003919 - FMN adenylyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HHS5223314.1"
                     /translation="MVIIKSIKEIANIKESVITIGNFDGVHKGHQVLIGKTVEHAKKE
                     NIQSIVFTFANHPVNYFRPNSTKNIISNDDKIKLLEDLGIDIVVIIPFDEYMTKIPAK
                     DFVDEILVKKLKAKKIVIGHDFTFARAKEGNVNLLKSLEHEFGFEVEVIKPIKINDVR
                     VSSTYIRSLVSQGDMANVKEYLGRNYKLEGCVIHSKHLGRTIGFPTANIDLKNNMLVP
                     KRGIYASIVHIGDETYFGATNVGYNPTVNGKTLSIETNILEFDRDIYGENIIVEFLER
                     IRDERKFNSIDDLKNQLYNDTNYVYENYVCKNK"
     gene            16110..16367
                     /gene="rpsO"
                     /locus_tag="KRH23_000015"
     CDS             16110..16367
                     /gene="rpsO"
                     /locus_tag="KRH23_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002843739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HHS5223315.1"
                     /translation="MINKSEIIKEYGRAEGDTGSPEVQIALLTARINELNGHLKTHKK
                     DHHSRRGLLKMVGRRRNLLAYLKEKDLEGYRALIAKLGLRK"
     gene            16607..17452
                     /locus_tag="KRH23_000016"
     CDS             16607..17452
                     /locus_tag="KRH23_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008289 - lipid binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HHS5223316.1"
                     /translation="MKIKLVCDSLCDIPDEISEKDYIEIVPLTVIFNDREYIEGVDIK
                     KEEFYKKVKEIKQIPKTSQATYMEFKEVFDKFITEGYHIICMTGAANASGTFQSAMIA
                     KNDVNENEKIHIFDTRNLSLGSGQYVIKACELLEEGLGFEEIIDELENTRSSVRLLFA
                     PYTLDFLKQSGRVPVATALIGNMLNIKPIFFFDNGEAKLVNKVRGIKNIASKLVDIIL
                     EMNEGSLEGKIVTIGCGDNLHDCEILKDEVNKRIKARRVLFTRGGVSICSHTGPDILA
                     ISCSN"
     gene            17577..19688
                     /gene="pnp"
                     /locus_tag="KRH23_000017"
     CDS             17577..19688
                     /gene="pnp"
                     /locus_tag="KRH23_000017"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004654 - polyribonucleotide
                     nucleotidyltransferase activity [Evidence IEA];
                     GO_process: GO:0006402 - mRNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HHS5223317.1"
                     /translation="MFEHKIFKMDFAGRELSVEIGKICEMASGSCIVRYSDSMVMVNT
                     TKSAKPRDGIDFFPLSVDYEEKLYSVGKIPGGFLKREGKPSEKAILTSRLIDRPIRPL
                     FPKGFRNDVQVVATVLSVDQDCTPDIVAMIGSSIALSISDIPFNGPTGSVCVGLVDGA
                     FVVNPNAEQREKSSMHLVVSGTKEAIMMVEAGADEVPDEVMLDAILFAHQEIKKIVEF
                     IEGIVAEVGKEKMPVELYHAGEEITQLVREFATDKMKKAVQTFEKLERMENMDRVKEE
                     TLAHFEETLEDFEDFVGDIEEVLQDIIKEEVRKLIVHENVRPDNRKLEEIRPIWCETG
                     MIPRAHGSAIFTRGQTQVLNVATLGALGDVQKLDGLDEEENKRYMHHYNFPAYSVGEA
                     RPSRGPGRREIGHGALAERALLPVIPSQEEFPYAIRLVSEVLSSNGSTSQASVCGSTL
                     SLLDAGVPIKDMVAGIAMGLIKHDGKVAVLSDIQGMEDHLGDMDFKVAGTEYGITAIQ
                     MDIKIDGIDKEILQRALKQAKEGRIHILGEMRKTISQPKPELSPYAPKIVKMQINPDK
                     IKDVIGPGGKIITKIIDETGVKIDIEQTGEVFISGIEIDMIKKAQELINNIVVEPEVG
                     KTYKGKVSRIMNFGAFVEILPGKEGLLHISHIAHERVAKVEDVLNIGDEVEVKVTEID
                     EKGRVNLSRKVLLPKPEHKNK"
     gene            19954..20697
                     /locus_tag="KRH23_000018"
     CDS             19954..20697
                     /locus_tag="KRH23_000018"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HHS5223318.1"
                     /translation="MIMMVLNKSKLKKIIILILVVLLVLSGGVMVLKLFNNKPVFNLF
                     NGVDLPYERGTKDKSGYVALTCNIDLGWETEYVESILETLKKENVKITFNVTGKWAEK
                     NKDELLKIKKQGHEIGNHGYKHLDYSTLSYEDNYEQIETSKKIIEEIIGEKTKFFQAP
                     AGSFGPETVKAAKALGYTSIKWDADTIDWKYKDQPEVIIDRMKKKDIKDSSIILMHPT
                     NATTKCIDDIIAIVREKGLKPGKLSDVFK"
     gene            20855..22102
                     /locus_tag="KRH23_000019"
     CDS             20855..22102
                     /locus_tag="KRH23_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008237 - metallopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M16 family metallopeptidase"
                     /protein_id="HHS5223319.1"
                     /translation="MYKTKILENGLTIIGEEIPYLKSITLGIWINAGSRIEEAQVSGT
                     SHFIEHMMFKGTKNRTSKEIASSIDNLGGQINAFTSKECTCYYVKLIDEHIDTGIDVL
                     SDMILNSKFDKNDIDKERLIILEELKMYEDSPDDLSYDLLVENIYANDGLGMNIIGTK
                     ESLYNITRESMLEYLNKYYIPNNAVISIAGNFNFDDMVEKIKSKFGHWEKKNLSIDIS
                     EAKFNPCFISKNKDTEQVNLAMCLKGIPFENDEEVYSMAVVNNIFGGSISSRLFQKIR
                     EEKGLVYSIYSSQTLYRKCGELGIFASMSTENLQDVYNLIKKEIENIRENYLTEKEIS
                     ESKEQLKGNYILDLESTSSRMMSTGKSMLLSKKVKTTDEILECINNVNINSIKKVVDK
                     VFNIENIGTCIVGRDVEKILHLD"
     gene            22137..22382
                     /locus_tag="KRH23_000020"
     CDS             22137..22382
                     /locus_tag="KRH23_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YlmC/YmxH family sporulation protein"
                     /protein_id="HHS5223320.1"
                     /translation="MNLSEIAGKEIVNLVTGERLGVIGECDLILDETTGGILALLIPK
                     EKGFFARRKDKSFLEVPWRNVKKIGNDMIIIEYEGYI"
     gene            22392..23615
                     /gene="dapG"
                     /locus_tag="KRH23_000021"
     CDS             22392..23615
                     /gene="dapG"
                     /locus_tag="KRH23_000021"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004072 - aspartate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HHS5223321.1"
                     /translation="MSILVQKFGGTSVESYEKMNEVCKIVKAYKKNDEELQLVLVVSA
                     MGRKGAPYATDTLINLCSAVNDEPSKRELDLIMSCGEIISGTILANLLNAQGIDSVFF
                     TGQQAGIITSDEYSNAKIKYINPKKVKRALDDGKVVVIAGFQGVTDDGEITTLGRGGS
                     DTSAVAIGKALECETVEIYTDVDGIMTADPRVEPNAKVLSFIDYEEVFQMADKGAKVI
                     HPRAVQLAKSGNITLAIKNTMNPTFEGTKIGSLCRHLEDNIEYEQERDFKVAVANKDS
                     VAQVKIKSAEEVFTEVLNEIEKKLITIDMINFFISEKAFVVEDADIKSLKEILDKFEL
                     DYEVNRDCAKVTLICSRIADEMSGIMSKVVRGLSKAGVSLLQTSDSNMTISCLVSEED
                     MHTAVHAIHQQFYLK"
     gene            23728..24462
                     /locus_tag="KRH23_000022"
     CDS             23728..24462
                     /locus_tag="KRH23_000022"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004176 - ATP-dependent peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0051117 - ATPase binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ClpP family protease"
                     /protein_id="HHS5223322.1"
                     /translation="MKDYREDNERFDKDNCSEESSCEERECIKQFGTNEMPPQPPKDI
                     QCITIIGEIEGHFIGNPQKKATKYEHIIPMLYSIEESNDVKGVLVVLNTVGGDIEAGL
                     AIAELLNSTSKKVVTLVLGGSHSIGVPLATAGDYSFIAPTATMIIHPVRTTGLVIGIN
                     ETFEYFKKMQDRIIQFIIRTSNIKKDVLEKLMHEKDELVSDVGSVLIGKEAVDYGLID
                     EVGGLKEALKKLRELIKESEEEKNND"
     gene            24585..26996
                     /locus_tag="KRH23_000023"
     CDS             24585..26996
                     /locus_tag="KRH23_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HHS5223323.1"
                     /translation="MATKKKKKKKVNTLSFNAEYHNLITIFIGVFLLYSLNSNSMGWI
                     PVLMQNLFKGLFGGLSIAIPFIVIITGLLGFFDGNEYIYRLRKTKLYYIIILFIFVFY
                     GLLNAGTLPVDSPLKGNMFDDVMKLGVSGQGSGLIATTIAYYMSKIFGIAGGWLISIF
                     ALILSVMFIFNISIKDLVSNAKSKSKASKDSNLTFKDKIANMKKSAIDMMTDEVDDTT
                     INKKPGFFKGLMSKGLNNDDEEDEYFEEENSDGVDDKTIKIVGFNKAEDEYLEILEGT
                     QSMPELDVLKELQKATNENPVVDTKPEKKVDIAKPNLNIEKTQPMSIVAEPVNEDYSN
                     YKKPSIELLNKVNKKSDENGKKKVLKNASLLEKTLSDFGVEAKINQVTVGPTITRYEI
                     QPSPGVKVSKIVNLTDDIALSLAAKSIRIEAPIPGKSAIGIEVPNEEAQMVGVREVLE
                     SEEFNNFNSPLAMGLGKDVAGKIIIGDIGKMPHLLIAGSTGSGKSVCVNTLISSILYK
                     ANPDEVKLLLIDPKVVELANYNGIPHLLIPVVTDPKKAANALNWAVTEMNRRYKLFAD
                     AQVKDVTSYNEKAEEKLPKIVIIIDELADLMMASANDVEDYICRLAQMARAAGMHLIV
                     ATQRPSVDVITGVIKANIPSRIAFAVSSQTDSRTILDMGGAEKLLGKGDMLFYPLGAA
                     KPVRLQGAFISESESEKVIDFVKSQVKDGIKYEEDIIETISKVNTSKGSDEDEFLSEA
                     IEFVVESGQASASMLQRRFKIGFNRAARLIDSMEERGIIGASEGSKPRKVLISKQDLQ
                     NLEGE"
     gene            26999..28057
                     /gene="mnmH"
                     /locus_tag="KRH23_000024"
     CDS             26999..28057
                     /gene="mnmH"
                     /locus_tag="KRH23_000024"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-selenouridine(34) synthase MnmH"
                     /protein_id="HHS5223324.1"
                     /translation="MSVIKIEKALKLDKVIFVDVRTEGEYEEDHILNAINMPLFKNNE
                     HNEVGTIYKMQGKHEAIQKGFDYVSYKLKDIYLQAAELALNYDNIVIYCARGGMRSGS
                     IVNLLSSLGVNVYQLEGGYKAYRNFVLEYLRHVMDTKNFVSVHGLTGTGKTDLLHLLD
                     EKGIDVLDLEGIAKNSGSTFGFITFDKKPPSQKNFETKLFESIFFSKENYIFVESESK
                     RVGSVTVPNEIFEAMTREGHHILLECDIENRVDRLCRDYIYDKDEGNILILKECINKF
                     RKRLGNKVVDDYIDLLESGEYKELVKRYLLEYYDPLYMHSVEKYKYSKIINFNDTQKA
                     LEDVIDLYESILEGESEC"
     gene            28051..29385
                     /gene="rimO"
                     /locus_tag="KRH23_000025"
     CDS             28051..29385
                     /gene="rimO"
                     /locus_tag="KRH23_000025"
                     /EC_number="2.8.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008172 - S-methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016782 - transferase activity,
                     transferring sulphur-containing groups [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0018339 -
                     peptidyl-L-beta-methylthioaspartic acid biosynthetic
                     process from peptidyl-aspartic acid [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12 methylthiotransferase
                     RimO"
                     /protein_id="HHS5223325.1"
                     /translation="MLKIALESLGCSKNLVDAEIMMGILNNKGYKLIGDFEEADVIIV
                     NTCGFIESAKQESIDTIINFAELKKTGNLKLLIVTGCLAQRYSEELKTEIPEIDAIVG
                     TGSYQNIDKILKELSEMHQIVSLNDIEFVFNEDLPRYISTPSYMAYLKIGEGCSNNCT
                     YCIIPKLRGKYRSRKFEDIIKEAKKLAESGVKELVVIAQDTTKYGFDLYGKERLSELL
                     EELAKIDGFKWIRVMYSYPESITEELIQVIKKYDNICSYFDMPIQHASNNILKLMNRK
                     TTKEDILNKINLIRSNIPDAILRTTIIVGFPGETEDDFKQLVDFVEEVKFDRLGAFAY
                     SREEDTPADRLPNHIDEEVKIQRRDTLMMIQQKISEELNDKKIGKTYEVLIEEQIEDN
                     VYTGRTQGDAEEIDSIVYVKSVDNLEVGEFVSVQINDAMEYDLMGDVLYELA"
     gene            29372..29914
                     /gene="pgsA"
                     /locus_tag="KRH23_000026"
     CDS             29372..29914
                     /gene="pgsA"
                     /locus_tag="KRH23_000026"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008444 -
                     CDP-diacylglycerol-glycerol-3-phosphate
                     3-phosphatidyltransferase activity [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HHS5223326.1"
                     /translation="MNLPNKLTLFRIFLIPVFVLIMLLNIPNKFLIACIIFIIASITD
                     ALDGKIARKYNLVTDFGKFMDPLADKLLVISALTCMIEDHLVSSWMVIIIVARELTVS
                     ILRAIAAADGKVIAAGNSGKLKTITQMVSIVFLLLGAQFENVLILNIGEILILIATLL
                     TLYSGWEYLYKNKELFMSSK"
     gene            30202..31248
                     /gene="recA"
                     /locus_tag="KRH23_000027"
     CDS             30202..31248
                     /gene="recA"
                     /locus_tag="KRH23_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008094 - ATP-dependent activity, acting
                     on DNA [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HHS5223327.1"
                     /translation="MSVDQEKLKALNEALGKIEKDFGKGSVMKLGEATSMSIDVISTG
                     AIGLDIAIGIGGLPRGRIVEVYGPESSGKTTVALSCVASAQKDGGIAAFIDAEHALDP
                     VYAKALGVDVDNLIISQPDTGEQALEIAEALIRSGAIDIIVIDSVAALVPKAEIDGDM
                     GDSHVGLQARLMSQALRKLTGSIKKSNCVAIFINQLREKVGIMFGNPETTTGGRALKF
                     YSSVRLDVRKIDTIKQGDKVIGSRTRVKVVKNKVAPPFKQAEFDIMYGEGISKIGDLL
                     DIAADVDIVKKSGSWYSYNDTKLGQGRENVKKFLEDNLDLTTEIDEKVRAFYNLNEEH
                     EESGTSVSKEIVEE"
     gene            31424..32965
                     /gene="rny"
                     /locus_tag="KRH23_000028"
     CDS             31424..32965
                     /gene="rny"
                     /locus_tag="KRH23_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006402 - mRNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HHS5223328.1"
                     /translation="MDVIDSVVMIVIGAAVGIIAGYFVRKNISEAKIGQAENLAKEII
                     DKAHHDSETVQKEKLLEAKEEIHKWRTEAERENRERRTEVQKYEKRVVQKEEVLDRKL
                     QNLESKEVNLSEKLKVVEKKEEEVEVIKTQQLEKLESISGITSDKAKEIILTNAERDV
                     RREMSIMIKEIESQAKEEADKKSREIIGYAIQKCAADHVAETTVTVVSLPNDEMKGRI
                     IGREGRNIRTLETLTGIDLIIDDTPEAVILSGFDPIRREIARIALEKLIADGRIHPAR
                     IEEMVEKARKEVDNIIKEYGEQAAFETSVHGIHPELIRLLGRLNYRTSYGQNVLKHSI
                     EVAHIAGIMAAEIGADIRLAKRAGLLHDIGKAVDHEMEGTHVEIGMDLLRRYKESKEV
                     IHAMSTHHGDYEPQTVEAVLVTAADAISAARPGARRETLEAYIKRLEKLEEIANSYEG
                     VEKSFAIQAGREIRIMVKPEAINDEEIHLLARDMTKKIEDELEYPGQIKVSIIRETRA
                     IEYAK"
     gene            33600..35381
                     /locus_tag="KRH23_000029"
     CDS             33600..35381
                     /locus_tag="KRH23_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UvrD-helicase domain-containing protein"
                     /protein_id="HHS5223329.1"
                     /translation="MSQYININSQLDALKLKEFEKIFYENINEDVKVVPKVTPFKGIN
                     TDLLYVKDGRILFIKFMDTTEDIFFILEEELLEVMNEEYELLKLKMGQKNRNISYNYV
                     YIMPYVEVEETYEFEEFVNNNIIDKNKLQDIMNKGSLEEYLNDENDEINLNLFLLDIC
                     SEYYIINDKLHLNEKFKKISFYNDDYKYTATMMEDVQIKDVVSIKYGNTLIEGGSGIG
                     KTAIMLSRAIKLAKVYPHHKLVIFTHTKQLCNELRERIELLYKDNNNLEVHTFSSFIF
                     KLAKKFNLIVDYNMLKNDYEKTFNNLVKQAQNIIKNKNMFKAIFIDEAESFLEYEIDF
                     IREFLYKTKFIFNVCSCNSLNISNRLNIFKKLYNGIEFDDKIILSKNYRQAKEIVDFT
                     NKFSNNSNSYINELRPNTEFSTFFYTKALRGGNKSVDIIKVSDLDDQISSVIWEIEYL
                     ISKKGLDYSEVAIVYPYNKKKLKSGKTIYFQYMLKKALEEAKIPYICAEDNLTNISKK
                     VGTTIANIYAIKNLEYKAVIVCELEMLYNQTINDIEQDYQVNDFVGDLNKVYLAMSRA
                     TDYLSIVTTFNEEASDIIRLITESKDI"
     gene            complement(35463..35993)
                     /gene="lepB"
                     /locus_tag="KRH23_000030"
     CDS             complement(35463..35993)
                     /gene="lepB"
                     /locus_tag="KRH23_000030"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HHS5223330.1"
                     /translation="MSVKKEIFDWIKSIAMAIVLAFVILQFIRPSIVSGESMYPTLDD
                     KDYLILNRISYKVGKPEKGDIVVFKTNLVDGETGKKKDLIKRVIATEGDRIKISNSKV
                     YVNGKLLNEPYIHNNYTSGDIDTVVPKGKLFAMGDNRENSNDSRFPDVGMVDEDEILG
                     KVMVRLLPLDNIGKVD"
     gene            complement(36033..36857)
                     /locus_tag="KRH23_000031"
     CDS             complement(36033..36857)
                     /locus_tag="KRH23_000031"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0050380 - undecaprenyl-diphosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0016311 - dephosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HHS5223331.1"
                     /translation="METFSLLEIFKAVILGIVQGITEWLPVSSTGHMILVDEFIKLNF
                     SNTFISTFLVVIQFGSILAVLVIFFRKLNPFDSAKNIKQKKETVRLWLKVIIAVIPSG
                     VIGILFEDDIDRLFFNSTVVAIALIVYGIIMIGLEKRNKKPKYKDFSQVTYKLALCIG
                     LFQCLALIPGTSRSGSTIIGAVLLGTSRYVAAEFSFFLAIPTMLGASALKLLKAGFGF
                     TGFEWLILGVGSVVAFVVSIVVIKFFMDYIKKHDFKVFGYYRIVLGIVVLAYFFLL"
     gene            37114..38022
                     /locus_tag="KRH23_000032"
     CDS             37114..38022
                     /locus_tag="KRH23_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009009 - site-specific recombinase
                     activity [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HHS5223332.1"
                     /translation="MYSTKILDDYEYETFNVFSTKLNPNTKHDYLSKVILFKEFLKGK
                     ELIYATKEDCKNFVDYIQTKYAKSTCEKIYSYLHSFYNFLKKEGYIDINPFRYVEKPT
                     VTRIKTKDDVLSIQEINKLIGILPKLNIRDRVIIVCLVTTGCLLNELVSLKWKDLMVD
                     ENDNSYVRLGKGRKERVVKLHPYFFKLLEDYRNYSGLPEVIIPSDDFIFTTQKSNSIT
                     DRNVRLIVKKALDLAGLSQYSARDFRHSFAAISLRLGADESDVKNQLGWSDKYYAIRY
                     KYVLNFVDSEIVDYLIEKDNLDINKK"
     gene            38166..39611
                     /gene="purB"
                     /locus_tag="KRH23_000033"
     CDS             38166..39611
                     /gene="purB"
                     /locus_tag="KRH23_000033"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004018 - N6-(1,2-dicarboxyethyl)AMP
                     AMP-lyase (fumarate-forming) activity [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HHS5223333.1"
                     /translation="MIDNKYTTYSNPLTDRYCSKDMSYIFSPQFKFSTWRRLWVALAE
                     GEHELGINITEEQLDELRANIDNINFDEARKIEKEVRHDVMSHVKAYGLQCEKAKGII
                     HLGATSAYVGDNTDVIQMNEALKLLRVKLVNLINNLKEFALKYKDMPALGFTHFQAAQ
                     LTTVGKRACLWAQDLILDLEDLNYRIDNMKLRGVKGTTGTQASFLSLFEGDHEKVKEL
                     DKKICKKMGYHSSYAVSGQTYTRKLDYQVISILSGIAQSMHKMTNDIRLLQSLKELEE
                     PFEKNQIGSSAMAYKRNPMRSERIASLSKYIISESISPAMVQATQWLERTLDDSANKR
                     LAIPQAFMAADAILEIGINVTDGLVVYENMINRRVNEELPFMATETILMEAVKRGGDR
                     QELHEIIREYSMKAAYRVKHEGKDNNLIELIMNDDSFKMSKEEILSIMDPKNFIGRAP
                     EQVVEFVNEVVEPAIKDYKEDLGKVDVDLRV"
     gene            39922..40374
                     /locus_tag="KRH23_000034"
     CDS             39922..40374
                     /locus_tag="KRH23_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HHS5223334.1"
                     /translation="MNYIVKDTISFLVKTFPKIYSSLYLEDLKKFAPDYNVNKTQLRA
                     LVFIKNYGVISMTDLCSKLNIEKGSLTSMVDDLTDKKYVTRKRDLVDRRKYLIDITEE
                     GDKIATDFMDKLSDGLGEKLSKLTEEDRKKYLEAINTLQYILNKEEFR"
     gene            complement(40709..41905)
                     /locus_tag="KRH23_000035"
     CDS             complement(40709..41905)
                     /locus_tag="KRH23_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HHS5223335.1"
                     /translation="MNYSNRVSAMQASPIRKLVPFAQAAKDKGIKVYHLNIGQPDIKT
                     PKGFFDAVKNFDSEVLEYATSEGIPELLEALQNYYKTYDMNFEKDELLVTNGGSEALL
                     FTMMAVCDPGDNLLVPEPFYTNYNGFGQSVNVEVNAVTTKAENGFHLPSKEEILSKVD
                     DKTKAIILSNPGNPTGAIYTKEELNILAEIAKEKDLWIIADEVYREFVYDGLEYTSCG
                     NLEGVQDRVIIIDSVSKRYSACGARIGSIACKNKGLIAQILKLCQGRLCVPTLEQIGA
                     VELYKTPVSYFKEVNEEYKKRRDVLYNELMKVEGVICKKPTGAFYIVAKLPVENAEDF
                     TIWMLKEFNKDNETVMVCPAEGFYATPGLGRDEIRLAYILNEKDLHRAATLLKEGLEQ
                     YVALQK"
     gene            42290..43240
                     /gene="galT"
                     /locus_tag="KRH23_000036"
     CDS             42290..43240
                     /gene="galT"
                     /locus_tag="KRH23_000036"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008108 - UDP-glucose:hexose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-1-phosphate uridylyltransferase"
                     /protein_id="HHS5223336.1"
                     /translation="MKELRIDPITNDVVIFATDRLKRPLDTADIPNEDEETNEYDEEC
                     PFCKGNEAHATDALFEIDSEEGWLVKSVYNKFPIIDDMARDVYGVHEVMIESDKHNRS
                     FYNMSQKEFEDVFFMYRNRFRDLSKDDKVEYVSIFKNFLRKAGASLMHPHAQILSMSF
                     IPPEITNELLVSKEYYDSNKSSLYDDLIENEISLDRRVVYNGEAFLVLIPYATKYSGE
                     VRIIFKDKIEFGELNDNNIQELSTIFEKLFKKLYNINGYMPFNLCIHTHPTKIETKSY
                     FNVHMHIIPRKYNFGGFELGTNMYVSSMSPEDLTKKLKID"
     gene            43401..44153
                     /locus_tag="KRH23_000037"
     CDS             43401..44153
                     /locus_tag="KRH23_000037"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HHS5223337.1"
                     /translation="MKFISWNVNGIRACVGKGFLDFFKEVDADIFCLQETKLQEGQIE
                     LDLPGYFQYWNYAERKGYSGTAIFTKKEPLKVMYGINIEEHDKEGRVITLEFEDFYFV
                     TVYTPNSQSELKRLEYRTRWEDDFIDYLTKLDNHKPVIVCGDMNVAHKEIDLKNPKNN
                     MKNAGFTKEEREKFSKLLDSGFIDTYRYFNPDKEGVYSWWSYRFNARKNNAGWRIDYF
                     CASKKLEDRLVSADIHTEILGSDHCPVELEMK"
     gene            complement(44245..45021)
                     /locus_tag="KRH23_000038"
     CDS             complement(44245..45021)
                     /locus_tag="KRH23_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004527 - exonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease domain-containing protein"
                     /protein_id="HHS5223338.1"
                     /translation="MEYIIFDLEFNQGFDKKLNKTVSNEKCPFEIIQIGAIKLDSKFN
                     IIDTFNSYVKPTIYKDIHPFISRMTNIKNSDFNDSPTFPEVYNNFIKFISSQDPILCV
                     WGAGDLKELYRNINYHKLPSNSLPKSYINIQQHASKYFNNPAGKSIGLQNAISILELD
                     EKMSYHNALNDAYYTAKVFIKIYNPSIVPDIYLYTSIKPKTIRYSNKKRVDYDKLFDE
                     FRKILNRELTKDEKKIINLAYNMGKTNQFTLENVKQRKNK"
     gene            45336..47234
                     /locus_tag="KRH23_000039"
     CDS             45336..47234
                     /locus_tag="KRH23_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HHS5223339.1"
                     /translation="MDSLLYVIEKDKHTNEELREILKSNKNIRFVSLMGVDLGGNATD
                     EKIPVELFLEDIDKFLESAIQTDGSSVELYNIATLNNAKVDLMPDKSCHWYVDYNMEY
                     IDEEVGLPVGTLKIPAFLIHDNKKVCSRGVLQKADKYFKKSMYEIFREYPHVINNIGI
                     DSVDDIEEIMLTAATELEFWVNTPEDKADLEKLYVSQSLKEQYWKRTHGIIRTCLEKS
                     LIILQKLGVNPEMAHKEVGGIQSSISIDGRTNHAMEQLEVSWKFSTPLQAADNELLVR
                     DVIEDVFTSHGLEVTFKAKPIHGVAGSGGHTHVGVSAKLKDGSIKNLFAPKDLKEDYL
                     SELGYGALMGLLYNYEVLNPIVTASNDGFNRLVPGFEAPVCIVTSLGHSYEIPSRNRS
                     VLVGLIRDMKNPKTVRFELRSPSPLSNTYLVIAGCYQTMLDGIKAAAKSGLSTKELEK
                     ELSKNVGEESFYLEKDRAYRDENDVFEHYSLEERNARFGMPPATVYENMKNLEIYASK
                     LKSLKQGDVFTDSIIESFKIGAIDKWQKKLKTRIIEAGIQKIRSIVKIHTKENMDALD
                     EVVWNSISDLKFNIMKDTLTRESLFTRVREAIENKDYQTASDLQIELKRSMEEIQQLY
                     MQYKKNIY"
     gene            complement(47362..48483)
                     /locus_tag="KRH23_000040"
     CDS             complement(47362..48483)
                     /locus_tag="KRH23_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016758 - hexosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009247 - glycolipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MGDG synthase family glycosyltransferase"
                     /protein_id="HHS5223340.1"
                     /translation="MKDDKTILILTAQFGAGHISAAKAVKECIIEKYSNYNVVIQNFI
                     NASIPMMNKPMVKLYENNTKYTPGLYNYYYYFKKSFDSRHDLSHKLYTPKLSEYIADI
                     NPDLIISTFPLAAACVNNFKIKNPDINIPTLTVITDVVDSMEWVFENTDLYFVPSPEI
                     KNRFFQKGINPDSIKVTGVPVDKRFQIESKELCCDKYRLLLLGGGRGLFDIDEDFMHW
                     IDEFIEEHSNSIEITIVTGKNKKLYDNLTHKKPLKNIKVLGFVNDMYNLIRECDLMLT
                     KPGGATIFEAIQSQTPVLVKMPKVGQEIENAKFIIDKGLGMIYSDDLDLKNIFYKLVS
                     NEFDSIINFMKKNLKEFKTVIHPEKIADYISELIDNHYS"
     gene            48682..49014
                     /locus_tag="KRH23_000041"
     CDS             48682..49014
                     /locus_tag="KRH23_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HHS5223341.1"
                     /translation="MNTQFRKGVLEICVLALISKKDMYGYEIVHNISKVIDVNEGTIY
                     PILRRLTKDLYFETYILESNEGPARKYYRITSLGKENLSNLMEEWREFVKAVEILISE
                     DEGGNELE"
     gene            49001..50059
                     /locus_tag="KRH23_000042"
     CDS             49001..50059
                     /locus_tag="KRH23_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HHS5223342.1"
                     /translation="MNLNKTEFLEILKDYLKKDFSESEVNDILRDYEEYFVDGLIEGK
                     SDMEIIASLGSPKSIAKELILQTKEKNIEEEKIINTDVLNDKFSKFKSDMKKGYSILK
                     DEAKEKYSKSKENIDGKIMNTDILNGKFSRFKSNVKKDYSILKDEAKEKYNKSKENIN
                     DKLTPSIEEGVGGLSRQVIKGLLVVLSLFLIVPAFAFVCAIVSATIALVCSLIAFVIL
                     IPFVIKFIAMVPDVMMFCIFATIAFVGLEILAWQILLFAIKLGKQLLNNYIHWIKRKN
                     IYIKANEKMEKRKKATLNDEDLNKDINEDSYNNDYYNREEESIKETDEYNDDSINFEA
                     IYKDLEDIENKKGEDKYE"
     gene            50052..51122
                     /locus_tag="KRH23_000043"
     CDS             50052..51122
                     /locus_tag="KRH23_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat-containing
                     protein"
                     /protein_id="HHS5223343.1"
                     /translation="MNKKLAIFAAVLLVIGIIGTTWSGILVMPSLINFGLEKEAELNK
                     ENKLYQEKVNIDKLDIAVDNINVMIRKSSNEDVRVTTRGNNEFYKYSVTLQDKTLVVK
                     GERKSENKIKKIRSFDHLLNTSINSMFSRDYREIRIYVPNNVDINASSISSYLFISDD
                     VDSNNITYKTSSGGFSRAITENKVNRLENLNLISNSNLHLSTKSILGVKNVNIESESL
                     DISSENGDVFINNIEEYIPENVNIKEKIGRNSNYESEFYLYSDMPIAKFLDIEVPNSK
                     VRLDIPVNKYKFNCDIKSKEAIEEFNNDEEYDNDSYDYEHSEEHSNKYRNTREIKGLL
                     NKNLSNLEKEYTIKINSNSLEL"
     gene            51224..51760
                     /locus_tag="KRH23_000044"
     CDS             51224..51760
                     /locus_tag="KRH23_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HHS5223344.1"
                     /translation="MNKIAVSFLIIATTLLSTACMDYSISAVELVDSKESAVVKKDED
                     AKEETTSKMINSKKTTKIPIEIISKDEKIVKYLQIDEESSLKDKLRLILDTLSNEYFN
                     GLDMEVEVKEKDNLVKINLIEPDKKSRVSWKDDYLNEQNIIYTINNIIKNVIQEEDNS
                     IWIEEVEIYYNGKLIELR"
     gene            51876..52583
                     /locus_tag="KRH23_000045"
     CDS             51876..52583
                     /locus_tag="KRH23_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic protection ABC transporter
                     ATP-binding protein"
                     /protein_id="HHS5223345.1"
                     /translation="MSNYILQVKGVSKKFKEQMAVDNISLAIKYNSIYGLLGPNGAGK
                     STLLKMITGILNPTSGKIMFEGHRWTRKDLSNIGSLIESPAIYENLTARENLKVHTTL
                     LGLPDSRIEEVLETVDLRDTFKKRSGQFSLGMKQRLGIAIALLNHPKLLILDEPTNGL
                     DPIGIEELRELIRSFPKQGITVILSSHILSEVEQVVDEIGIISNGVMGYQGEVSKEQN
                     LEKLFMKVVAENRKRGQ"
     gene            52585..53301
                     /locus_tag="KRH23_000046"
     CDS             52585..53301
                     /locus_tag="KRH23_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutE/EpiE
                     family permease subunit"
                     /protein_id="HHS5223346.1"
                     /translation="MERFIRVEFQKMKGTFGMKLIWIVPVFCILLCGLGGGQNAAFNW
                     WYTTFLPGALTLISSLIVLKDEKSKYRGILPLPIEMKDVWTGKMIYCIICCFIASIIS
                     AIGVVFVGIIYKETISIGQNIIATILIILLFMWQIPLCMFLASKFGIFVTVLINMFFT
                     IVGVAVFSTTEMWYMFPYSIPSRLMAVVLHILPNGLPVPEGSEFLNNAVILPGVLISI
                     VLFVLFALATRVWFNNREVK"
     gene            53303..54061
                     /locus_tag="KRH23_000047"
     CDS             53303..54061
                     /locus_tag="KRH23_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutG family
                     permease subunit"
                     /protein_id="HHS5223347.1"
                     /translation="MRQLIRIFCSDLIKLKRNFIILMHICIALMGMGLFLWYYKVSGA
                     DNILKIVAYLQVIAIAFPLLSGVVCSMFVEQEYYAGNYKHMLTTSNPKYLTLISKYII
                     LVCLGFVATLVSVLGFKFGISKAYFASSFYMISILILIGCNLFEYILHLFLSLRFGKG
                     TSIGVGIVEMLLSALLLTGLGSGIWQYFPCAWGVRFITIWSSFSSSKTVEYIKVESIK
                     AYQSTGLMCGFVTILAFVILCIWFSKWEGKKSEE"
     gene            54207..55595
                     /locus_tag="KRH23_000048"
     CDS             54207..55595
                     /locus_tag="KRH23_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase"
                     /protein_id="HHS5223348.1"
                     /translation="MLGGKKSNNKKVEKLRTIFIKYLSLFFIMTISIILILMLLFSWL
                     LSSGVILPANYAEKQFNKYKEKIISSEKVTEDIIPNIYEYGVYTLDGNLISGTFNKKE
                     SKEVWNLMRDIEERHAYSESYIKFFKKDKVFIIKYKIVSEYSSPILRAYLPKPETLGM
                     IIFSIIFFIEIVILSKVFGKKFNIEMELLKNTTEKIEQQDLDFVVESSKIYEINNVLF
                     SMDKMKLALKESLEKQWMLEENRKEQISALAHDIKTPLTIIHGNTDLLIEINENPELL
                     EYMEYISKGVTQIEKYINTLIDISKTENGYILNKEAISMSEFIKDVLVQIEALASTKN
                     LDVEFYKQDNLPKNITIDRELLFRAIMNIISNAIDYSPSQSKLYISVSVCNKYLKFIV
                     TDCGSGFSKADLSKATEQFYTGDLSRNSKSHYGMGLYIVNNIVQKHNGILYIENSVKT
                     GGAMVTIEIPIV"
     gene            complement(55671..56492)
                     /locus_tag="KRH23_000049"
     CDS             complement(55671..56492)
                     /locus_tag="KRH23_000049"
                     /EC_number="2.7.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008478 - pyridoxal kinase activity
                     [Evidence IEA];
                     GO_process: GO:0009443 - pyridoxal 5'-phosphate salvage
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine kinase"
                     /protein_id="HHS5223349.1"
                     /translation="MQKKVAAINDLSGIGKCSLSVAIPILSALKVQCCPFPTAILSSQ
                     TGYPEFTFLDFTDEMVKYSNVWKNLKVNFDSIYSGFLGSKHQIEIVANFINDYPNAFI
                     VVDPVMGDNGVMYPIFTEEMRQEIKELVKHSDLTTPNLTEACFLTGNDYTKSDYNRDE
                     LIYIAKSVSDLGPSKVVITGILEDDNILNLAYDRDNDHVFFTSVKYNNCSYSGTGDIF
                     TSILCGMLVNKHDLGVAVNTATDFIYKTINYTSQFDTDRNDGVMFENFLSDLTNI"
     gene            56743..57897
                     /locus_tag="KRH23_000050"
     CDS             56743..57897
                     /locus_tag="KRH23_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase domain-containing protein"
                     /protein_id="HHS5223350.1"
                     /translation="MKILKNKNKYIKGIMAFVFLSLATTAGVFLINDLSMKNMEEKVM
                     ESANVEGDDVKDQYKLLLENLFDYRNKAILEKNENILKGLYETDKKFGLWAYENEVKK
                     MKYLENWSSKQGVKFKDIKTRVKIKKIKEKEKDLYGIICSVSTEYKYSYENQKDKENA
                     FRIGTYHYLNVKIIDNQYVITKEWYTDPFADSLNLENIKSEDIRNYIGQQDGVELQLT
                     DEQKKAIDYAHKYCGAAADEEHGMKFNPNYRDYNPEGGDCANFASQIMFESGRFKKNS
                     IWNYSERAGTKAWVNAQAFKNYALYSGRGSLIAKGSYEEVYKEAYNLRPGDFVGYEKK
                     GRITHVSTVTGLDSRGYPLVTCHNTDRMLVPWDLGWSDKSIRFHIIKINY"
     gene            58080..58280
                     /locus_tag="KRH23_000051"
     CDS             58080..58280
                     /locus_tag="KRH23_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003230776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HHS5223351.1"
                     /translation="MKTGVVKWFNNEKGFGFISVEGEGDVFVHFSAITGDGYKTLEEG
                     QSVEFEVVDGAKGPQAANVVRL"
     gene            58701..59129
                     /locus_tag="KRH23_000052"
     CDS             58701..59129
                     /locus_tag="KRH23_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HHS5223352.1"
                     /translation="MNILFFLTPKSEVAYIYEDYTIRQALEKMEYHKYSAIPIISKDG
                     KYVGTITEGDFLWTLKNDLNLDLKGLEDVPVTDINRKMDNSPVSINADIEDLVIKSLN
                     QNFIPVIDDQDTFIGIIKRRDVIGYCYEIIRGYKNLANDN"
     gene            complement(59272..60027)
                     /locus_tag="KRH23_000053"
     CDS             complement(59272..60027)
                     /locus_tag="KRH23_000053"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HHS5223353.1"
                     /translation="MEKKVLATVGEKEITNIDIENALKSLDPYQAMQFKTEEGKKHLL
                     NDLVNQELFFLDAKEEKLDEEEIFKLEMKKIEENVLKQFAINKVLSSVNVTEDEKVKF
                     FEANKSSFSKPESATAKHILVDSDEKAKEILAQIKSEEISFEDAALKHSSCPSKDMGG
                     DLGTFGRGQMVPEFEEAVFSMAKGEVSEPVKTQFGYHIIKLEDLQESTESTFDEVKAE
                     VEKSLLYQKQNEVYGNKINALNAKYGNLVKYND"
     gene            complement(60728..61234)
                     /locus_tag="KRH23_000054"
     CDS             complement(60728..61234)
                     /locus_tag="KRH23_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HHS5223354.1"
                     /translation="MNNLDKLFELASQEEIIIHYTTYIAGDLEGLYINKHGIKIISLL
                     SNLKQNSKKLTSILAEELGHHFTSLGYYVSSYNDYYTKIIIDKCENKALKWACEFLIT
                     EEDIINIINSGITCVYEMADILNVDITFFQKRLEFLSLKKQSLQLGNNKYLILTNLPY
                     FYIFDPIS"
     gene            complement(61316..61636)
                     /locus_tag="KRH23_000055"
     CDS             complement(61316..61636)
                     /locus_tag="KRH23_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHS5223355.1"
                     /translation="MFAKRLRELRKEFGLTQRELGEKVGVSQRVLGYYETENRFPDEH
                     ILNKLADVFNVSVDYLLGRTLVKENIDTVAAHRKNPHEELPEEAQEQLNDYIEFLLNK
                     YKKK"
     gene            61805..62002
                     /locus_tag="KRH23_000056"
     CDS             61805..62002
                     /locus_tag="KRH23_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HHS5223356.1"
                     /translation="MFKNNLKYYRKCKGMTQIQLARKAGITNDYISQIERGIKNPGLL
                     MAKKISSILEQNIEEVFFIQL"
     gene            62107..62547
                     /locus_tag="KRH23_000057"
     CDS             62107..62547
                     /locus_tag="KRH23_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5223357.1"
                     /translation="MENKKDILFKETDKRLHNYKYLDIKIKNINLDIKRCENEYSGCG
                     AMVYTEKTSNTYNISSSVENEVLKREERLRKLKMEKEDIEIEKEKIENALTCLNDIEM
                     EFFNLFYNSKTKNNMTYISMKLHLDRTSCYNLKKKMIFKLSEIL"
     gene            62796..63239
                     /locus_tag="KRH23_000058"
     CDS             62796..63239
                     /locus_tag="KRH23_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail terminator family protein"
                     /protein_id="HHS5223358.1"
                     /translation="MLKYKEILETIIEILKKNFTESIFIDDESVQGSEGSCFFVSILS
                     VICTPVMLNTNNKDIVISIKYLPKPQSKSIRMYEVSDELNKLFNRNIKVTDRKLNITK
                     LEQSIKKEESIYVLNFTLTLNYLDSVYEEDVVYENMEEINLNLGE"
     gene            63244..64308
                     /locus_tag="KRH23_000059"
     CDS             63244..64308
                     /locus_tag="KRH23_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail sheath subtilisin-like
                     domain-containing protein"
                     /protein_id="HHS5223359.1"
                     /translation="MAIGLPSINISFKELATTVKERSARGIIAMVLKDAKALGLNEIH
                     EKEDIPVDLSAENKEYINLALMGNVNTPNKLLVYVIEGEADIQTALDFLETKEFNYLC
                     MPKAVEADKTAIKNWIIKLRDIDKVKVKAVLGKVVGNHEGIINFTTEDVLVGEKKYSV
                     DEFTSRVAGLIAGTPLSQSVTYTKLSDVVDIPKMTKVDAESKVNKGELILIKEAGAIR
                     IARGVNSLTELTAEKGEMFQKIKIVDTLDIIHSDIRKVIIDDYIGKVTNSYDNKCLLI
                     VAIKSYLEELEKSALIESDSTVEIDFEAQKSYLKSKGVDLSYMTLQEIKEANTGSKVF
                     LKAKIKVLDAMEDIDLSIEI"
     gene            64322..64750
                     /locus_tag="KRH23_000060"
     CDS             64322..64750
                     /locus_tag="KRH23_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tube protein"
                     /protein_id="HHS5223360.1"
                     /translation="MANMEARNVMSGTWGELWLDGNKVAEVKKFQAKMEFTKEDIIIA
                     GQMGTDTKYMGYKGKGSITLYHVSSRMHKLIGEKIKRGSEPRFVAISKLNDPDSYGAE
                     RIAVKNIAFDDLTLADWEVGVKGEIEAPFTFTEYDFLDII"
     gene            64876..65322
                     /locus_tag="KRH23_000061"
     CDS             64876..65322
                     /locus_tag="KRH23_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail assembly chaperone"
                     /protein_id="HHS5223361.1"
                     /translation="MSENGLSKNINIVDLLLNADTENLERPSTIVELKRLSTIFGQEF
                     KVMCRALTISKDEEIQNTCLKIDENMKTDIDLPEMQMLTIIEGVCDLDGKLLFKNKEL
                     MDKFKAPTPKELARKLLLPGEITNLYRILQDVMGYGKNAVIEEVKN"
     gene            65349..65516
                     /locus_tag="KRH23_000062"
     CDS             65349..65516
                     /locus_tag="KRH23_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5223362.1"
                     /translation="MYYYWKKKGIRPSLFYAMDKGELKLIEAFFALEIEEEVEKMKHG
                     YGVCPLTGGGM"
     gene            65516..67969
                     /locus_tag="KRH23_000063"
     CDS             65516..67969
                     /locus_tag="KRH23_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5223363.1"
                     /translation="MGNVREEGINMYLTDNYTPKMNQIISVTDNFRRATVAVSLSTNV
                     MASSIKNSIGSASNRVNSLNSSLRKVQTTASSVSSTMTKLSSSINAVSGVIGSLNGSI
                     MRLAITIAMIIDYFNKLIQKKNEFNSNIMIILIFKAKSDEVEKTKNKLLGNLKKIGGK
                     IWNIVIKAKDMTKRVISSILGKLKQVEKRPYQGSINLKDMVSSAMARILPKLMLFKNT
                     FWSGVIAIKDMASGIISKVFPKLRLFAGKVWSGAIAVKDMASGILGSIKGKISDLTNG
                     ATIGVAVKKGVDLLGQEQNQKVVLESVMKRNTGKVNQIDVDDYYGNLVRMANDTPFDP
                     EDVVAMGTKAKMISNITGGKKEKDITQAMVDVRALNMNTSSEQDVSAAFLSAAKGNME
                     SLNTLVGENYKTFDEALEGISVKQMGLAKEMSNTIPGIISGAQTSINNGLKSIVKPFD
                     DILGQGLKKIKTFIESGLGNLAGLSEKMAGKIGNVMNGKIIIGNKYDQMQSRSVKNGK
                     EFSDSTQYRISNEAEKRKMMVENKQERFENHAATMIGNAPKAIVNAGSTLLQNIDFTA
                     LIDSLLPVVNLVNNLLDSINNKSPIAQGLISIFGTIVTTAFQLIGPVVEAVSPIITRI
                     FTFLGEYAPQINNFIETLGVIWKTVWETLGPLLETGWKIIEPILGAFFNILDKVCKIV
                     KDICKWWQTMINKIKNGSITGTVLNLVEKSKKNYKDNPYAGTKAGDSGKAYSGKKGNN
                     AFGLNYVPYNDYQTRLHEGEMVLTKQEANQYRSRKNGGNINIAKLADTIVIREEADIE
                     KITSKLVASIQLAQLGGVL"
     gene            67969..68391
                     /locus_tag="KRH23_000064"
     CDS             67969..68391
                     /locus_tag="KRH23_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate protein"
                     /protein_id="HHS5223364.1"
                     /translation="MEMWLRQAEDRFRFPVFPSSFSINGKAAVNSSSILKIGEIATFG
                     GVALKSISISSFFPNKDYTFCDYTGFPSPYDCVNKIEKWMKEGFILRFTITETNINME
                     VIIEGFSYEERDGTRDVYFTLDLKEYKRIKIPKVTPKQ"
     gene            68511..70202
                     /locus_tag="KRH23_000065"
     CDS             68511..70202
                     /locus_tag="KRH23_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdQ/YqbQ family protein"
                     /protein_id="HHS5223365.1"
                     /translation="MVDKVSWSGDYKSPSRTLEFSIIQSSFDVNFQQIDIPIASTVCF
                     YVDEKELFRGMIINRSKDSSSNEISFVSKDMGFLLTQSEVSYNFKDKLVEDIAKQVFA
                     ENRLSVGTIAKTNVKYTKMFIGVNGYDTIMSAYTEASKKTKKKYMIEANLDKFNVIEK
                     GTVTLSVMFEEGFNIINTTFSESMENVKNKVIVVDQYGSKISEKIDNEIFKEVNVIMQ
                     KVIQQQENQDVDIDSEFNGIEKSCSLKGYGDVSCITGRGVKVKDSYTKLVGLFYIDTD
                     KHTWQNGEYQIELELNFQNLMDEKSAGQDEPKEESNLGGEDYAGGKEFTAEFTAYCPR
                     KEEGGDTDCRKKKLDPSKKTCAAPMVGKYEQTYYTKEFLNKHPLLNYGDEIQVITGVS
                     GRDGVYKVNDVGPAITIEKNGTYHIDILFGNVEEASKFGRRKGKIIIGGYSGNVSDKA
                     KIVISEAKKHLGKPYKWGGNGPSSFDCSGLMVYCFKKVNVSLPRTSNQQSKKGKKVEQ
                     KNLQAGDLVFFHNPVSHVGLYIGNGEFLHAPQKGDVVKISKLSSRRDFNTARRVL"
     gene            70218..70544
                     /locus_tag="KRH23_000066"
     CDS             70218..70544
                     /locus_tag="KRH23_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2577 domain-containing protein"
                     /protein_id="HHS5223366.1"
                     /translation="MANPINEFIGIIREEGKYHNQPSFFIGKIKSKLPDLKIETNNII
                     LEKEDILIDSWMIDRQLETFDTETNQEHQHEVKNPFIDNFESGDMVIMFRIGEKFAVV
                     SKLVSL"
     gene            70544..70972
                     /locus_tag="KRH23_000067"
     CDS             70544..70972
                     /locus_tag="KRH23_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2634 domain-containing protein"
                     /protein_id="HHS5223367.1"
                     /translation="MSTIFPFIGVPEDYILPKTEELPIFREVAWDFEKDEPILEKGDF
                     KIIEKKEALKVWIYKCIKTNRYEHEIYSLEYGTELSELIGQKYTKGLTESEASRFIKE
                     ALLINPYILEVNVKSANFNRDILSANVKVSTIYGEVEINV"
     gene            70965..72017
                     /locus_tag="KRH23_000068"
     CDS             70965..72017
                     /locus_tag="KRH23_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="baseplate J/gp47 family protein"
                     /protein_id="HHS5223368.1"
                     /translation="MYSDQTYEVIKNRTLENINLDIYKGEGSFLNNMVSGNNLELSKI
                     YLELSKMHKMAFIQDTYNQFLDKRVNEFGVYRKLGTESNGEVEFIGEKGTVINNGTII
                     SYRDLLFVVIKDVTIGSEEGDNSPVQTLEVGKKYNLPTNCEFKLVDNISGVTKITNTR
                     SFEGGTDIETDEELKERFYKIQRNQATSGNKAHYEEWALEVDGVYNVKVYPRWDGPGT
                     VKVLIFGKNNQAVDTETIERCQQHIDEEKPIGPTITVVTPLPIEISISAVMKLEDGYT
                     LDNVKESFLESINTYFRDIRGEIIYTKVMGILINTTGVHDLSNLLINGSTDNITINED
                     KIPSVTTVNFSEVENQ"
     gene            72014..72712
                     /locus_tag="KRH23_000069"
     CDS             72014..72712
                     /locus_tag="KRH23_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative phage tail protein"
                     /protein_id="HHS5223369.1"
                     /translation="MKLIDKLPSFDRNYIVEEIQGAYDTELNILKEDIDDTFNQLFVD
                     TATWGLDMWEDILCIEKKELDFDTRRSNIKAKMRSRGTSTIEVIKSICEAYTKSETDI
                     KVYSDEFTFVLSFIANNCDYKTLLDCSDMIERVKPAHLLHYLEPIILDKSMVYCGGGM
                     VCSEEVKVHPYFEPIIKCSAVVNCGAGMLSREEIKVYPLSIKCIENNCKINIAIANDT
                     GVENVVVYPKSEVV"
     gene            72713..73696
                     /locus_tag="KRH23_000070"
     CDS             72713..73696
                     /locus_tag="KRH23_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0098024 - virus tail, fiber [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HHS5223370.1"
                     /translation="MEEKFYIILTKIGREKIANATALGELVGLTKFQVGDSNGEYYEP
                     TEEQTALKNVVWEGNINSLRIDEKNPNWIVIETILPGTVGGFMIREAAVLDNENNIIA
                     IGKYPETYKPRAEDGSIKDLVVKMILQLSNTSNVTLEVDPTLVFVTQKDIQDLDDKVD
                     KNIKEIKVKIGEELLSTEAKNLSGAINEVVEKIKNISIDDVIGGQIQTELSVLKNSYN
                     KLSEKVLDILIYLELESEIDVDEAGYWYDTLTNAKNIIAIEGLKLDLNRKCITGELGS
                     VTFKNVVLPFNANRVRYIHEMDNNFVETKSNRAYSIGQTDITLNKYSYEIR"
     gene            73713..79034
                     /locus_tag="KRH23_000071"
     CDS             73713..79034
                     /locus_tag="KRH23_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5223371.1"
                     /translation="MKRTKLLQRGNFFGDKNMLVDEFDEGYDNYDFINFFTGCCNYTF
                     GLKNNNILYGCGDNSNFQLGLGEDNTTRKLFTKIPNISTNIKKVACGESHAVILTSDG
                     ELLVAGINTDGQMGLGLEKVGKTVSTFEKVPEIKGVKDIACGLQSTYLLYNDGTLYVA
                     GNNLYGQLGLGTNGASANVNTFTKVDVDNVKAVFSYNKSAFIIKNDNKCYSTGFNNQG
                     QLGLGDKNNRDLFSLVSINDVKTIACGSEHTVLMTYNNDIYGCGKEKCFGNALQSSLF
                     TKIEEVNIKTIACGNGNTMLIDNKGILKVAGNNDIYQLGIANYSENIDNSFIDLKNIV
                     AKNIFIGLSHSILIDSSNDSYCTGDNTYGQLGSFFDDMHIVEFKKMDSEKYSYSNYIN
                     LIKSEDKLTLLKEEMEIKDIELPLDIHSVRDVVFSPYCTLVILGNGDVYGLGNNRYKG
                     MGSDLPIQLNELTKLSISNVKSIVASKNISGGIFYIKNDDTCYYSGANSNSIAGVLPS
                     NSDVFKKISIDNVKKVVINTDLSNWFSLIVTNNKQIYTSGKSSGYVNGLSNKSASQYT
                     EIGVSNVTDAYSSYNATFIVADEKKVYATGINTNYLLGVNPNDGVNINLTLINNWFYV
                     NPSGASYSTNSCTNDITKINNIIIYEYMAILCTNYGSFLTGYHGTLWTKPSDSTYRVQ
                     QQGITHAGYISNYIYNYYPTRCTQSSYSTNFAYLYYGESTSNLKNVNPDNLLISGGSS
                     YIHQYGRNYLNNQSSNNIAASNINSGPITSDKAIFLYKALLYLSSNTLYGFGNISESA
                     KELDVSDTQDGYNATNYKKVMKNIKNIFIPPYDLSRDKTRFAILTDKSLFICGYNSKG
                     THGISVNSSLNLNNKINYNKKNSSSEISSNIQEIYSHSKSTYLLTNNNMLYSVGLNDV
                     GQLGVGDEINRKVFAKINIDNIKSISVNRFTDNSKHAFAIKNDNTCYAVGLNNSGQLG
                     IGDNVNRNVFTKINVENVKYVTIYGNTSLLLTNDGLLYGAGNNGKGQLGLGDTTSRNI
                     FTRIPINGVRDVYLCNDVSIIVKNDNTCYVCGFVNGYFGFTESSISTFTKINIENVKS
                     VVTAGSEATFFITNDNMIYTTGKKERVFFSTETNDIKGIRVINNIINAKKIVVNGYTS
                     AILTNDNKLFVGGLSGYGSITNNNNTNSVEDVKDVFVTANNTLYIDNNNNLISSGRDT
                     YGISDEYYMDIPVPYYKVSIKKDVDTVFSSYNTIFIKDIYGKFYSSTGDNRYNHLGIH
                     HRYDNDKNEALEGSLHSYFKTDNTSDKIVFNKKNEKLVMFNDKYIKTNNKYINYKNIF
                     KDNFKYTSIILPFEVSDIDISKTHSLAVAKDGKLYGIGSNSYKEINQTLEDIELLTFT
                     EVNISDVKKVACGDNYSYIIKTDNTLWSYGKNTEYQLGVGHNNDVRELQKVTGLPSVK
                     DISIYNSMTLVLTNEGELYAQGYNTNGLFGLGESEKDKIITTFTKVLTNVKEIKSHND
                     DHILVIKNDNSLWITGKNKSMYKISISITDLYEFTKIPIPEHLNDILDIELSDDTIYM
                     ITKVDTSKASIEIVEKSISQVRVVVQDPNNVIEKLEMFINDELISTKTNLEINSIIFE
                     IPQNKIVLGENKILIKASSPTGDLYSSMFIFKSETGLKVKKDSILMINNKVYSIINIT
                     ENNTDLIVTLNEGLKDDMMENNPIYQLINKTKVQVKINKSDLFKDMKLVEIKKSDSSY
                     QEIYELEEANIKSAQPKIIVEKGDKWTAIKRPSMIFRYDAENNEPQA"
     gene            79051..79404
                     /locus_tag="KRH23_000072"
     CDS             79051..79404
                     /locus_tag="KRH23_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CD1375 family protein"
                     /protein_id="HHS5223372.1"
                     /translation="MFKFDKNKIEQIKQGRKVEMQYKDISDISIGQVKQDDDITNNFI
                     ANAEIYEMLLNQSSVNEASNISSFSVRKSGGESGMVEVYVALILRGKKTIEEVPAVIR
                     EQVRIRCKELEIPVE"
     gene            79667..79927
                     /locus_tag="KRH23_000073"
     CDS             79667..79927
                     /locus_tag="KRH23_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5223373.1"
                     /translation="MDKLITELSSLGAIGILCALLFKNTMQEKKEDRDMYKKTVENFI
                     ELSTQQQEINKNILVQMGIMKTDVEEIKEDVTDIKGMLQNGV"
     gene            complement(80135..80590)
                     /locus_tag="KRH23_000074"
     CDS             complement(80135..80590)
                     /locus_tag="KRH23_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5223374.1"
                     /translation="MGLRDKFAQSFARSKTMSGPEKKANEIMGKLLLKKAILPIVLMF
                     VIIIAGAMLKINSWVTLGINLVIAVGAFFYIRNSSKKYQNFKPYVGNLISLEKKGKKE
                     YVAIIKQGKLPVKLQIAYGGEDLEHVKKNQMVQISYNPDAKIAILVNRQ"
     gene            complement(80818..81237)
                     /locus_tag="KRH23_000075"
     CDS             complement(80818..81237)
                     /locus_tag="KRH23_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHS5223375.1"
                     /translation="MDTLGERIVYLRKAKNLKQYELEEMLGCDNLSKFERNIRKPNYE
                     ILKSIAEIFNVSVDWLLNGDNLSHKSDLICDSSSNYPLNSINSNEIKLLNNFRKLNDY
                     DKAKIEGMIELKLHEYEKEKDLGKIEYNKNKDEKIDK"
     gene            81536..81745
                     /locus_tag="KRH23_000076"
     CDS             81536..81745
                     /locus_tag="KRH23_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HHS5223376.1"
                     /translation="MDARKKWIPFLGVQVKQRLIELNMTQRELAKKIGVNENYLSAIL
                     NGRRTGKKYKSSIYQLLNIEYSEDD"
     gene            81777..81986
                     /locus_tag="KRH23_000077"
     CDS             81777..81986
                     /locus_tag="KRH23_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5223377.1"
                     /translation="MCKLDSDGVIECCRAIDDFITALSNIKSLNMERLNTLTKYSSTC
                     SILLKEGNYEGCTIVYRKMLEELKT"
     gene            complement(82203..82601)
                     /locus_tag="KRH23_000078"
     CDS             complement(82203..82601)
                     /locus_tag="KRH23_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHS5223378.1"
                     /translation="MDTLGKRIAYLRNSKKLTQRKLMDILKFENLGKYETGDRKPNCD
                     ILMSIADYFNVTTDWLLYGKEKVNVNSSVKEDKEDYLHVTNDEMTILNLYRQLNERDK
                     IKIEGILELKISEYKDLKKHSSNNNEDKMV"
     gene            complement(83022..85514)
                     /locus_tag="KRH23_000079"
     CDS             complement(83022..85514)
                     /locus_tag="KRH23_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HHS5223379.1"
                     /translation="MNHNTSIKNKDSNPKIFLVLTLYLLGIFMGAIDTGIVSPARTII
                     QNSLGVNEKTGIWMITIYTLTYASVIPISGKLADKIGRKYVYLVSIFLFGSGSLICGL
                     SSLFSNFYILLIGRVIQAIGGGGIMPIATAEFGTTFPENKRGMALGLVGATYGIANIL
                     GSSIGSTILSIFGTQNWKWLFFVNLPICLIILIGGVFCIKNNKSESKEKIDKLGTLML
                     ICIIVSLLYGLMNIDFFNFKNSIQDISVYPYLLTFIVLIPIFIFIENRAKDPILSFEY
                     FLNPRILIVLILSLIVGIGMMGMVFVPQYAENALKINAGSGGYFVAILGLFAGIAAPL
                     SGRLIDKFGAKKILLLGFSVSMIGSLYLVLIALKTNTVFSVCVSLIFMGLGMGFTMVT
                     PLNYMMLSNTRLEESNSALATLSLIRSIGTSISPAIMIGFIAHAGLSVQDNIMDLVGK
                     PSTPKIVQLEELENMIDDLKSDPEMAKNLKNVSIPNMNDTSNINMDMTGGKLPKSLLN
                     KVQSADTTNITNITKEISTTMFDEKVPSIITKIQKNVQKGIDGTQSGINGIEDGENKL
                     NSGIKGVQTGIDNMVKARAGINQGIDGVKKGIAGVDKGIKGMEQGLEKQDEAIKELTT
                     AYNKIPTTEKTPTDNENNSNEQNQSNTSNSESDDTKNDSTENKNNNSSENKPNVNEQK
                     ESLNAQIQQLKKTRDDLNTKLQKNKTQKNELSKKLRSMESQKKELQSKLNNSISQKKD
                     MEKSLDTMQQQKKSLQAVLAKTQEVKTEIPKAFDKSKLDYINSIENNRTKIENTLQST
                     LNSGFKQMYITVFCVNLLAFIILLFYKENKTR"
     gene            complement(85528..86070)
                     /locus_tag="KRH23_000080"
     CDS             complement(85528..86070)
                     /locus_tag="KRH23_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HHS5223380.1"
                     /translation="MPKILENVKEDILKVSRDMILEEDYSNISIRKIAQRCGISAGTV
                     YNYFNSKQEIIEYITKSEWDLLIRRIEYSNKNTEDYIKKLNIIFTEIRNFINKVHNIQ
                     YNDFLNTFETERFFEMKKHKDDFHEQLSNKVYEALEKESFFNNDKLVCNIIIKMFFSY
                     STYLHIEFEDLKPYIEKLIH"
     gene            86314..87828
                     /gene="glpK"
                     /locus_tag="KRH23_000081"
     CDS             86314..87828
                     /gene="glpK"
                     /locus_tag="KRH23_000081"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004370 - glycerol kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006072 - glycerol-3-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HHS5223381.1"
                     /translation="MEKKYVMALDQGTTSSRAILFNKKGEIVKIAQKEFNQIYPKAGW
                     VEHDPMEIWGSQSGVMREVIETAGIRPEEIASIGITNQRETTVVWSRYTGKPIYNAIV
                     WQCRRTSEICDELKNKGLEESIKEKTGLLIDAYFSATKVKWILDNVEGAREKAEQGEL
                     LFGTIDTWLIWNLTRGKVHVTDYSNASRTMMYNINDLEWDEDILRELDIPISMLPLVK
                     PSSYVYGHTDERMLSGAKIPIAGCAGDQQAALFGQNCVEEGTAKNTYGTGCFLLMNTG
                     SNIVKSKHGLLTTIAWGVDGKVTYALEGSIFIGGASVQWLRDELKIIESAKDSEMYAN
                     RVDDTNGVYVVPAFTGLGAPYWDMYARGSILGLTRGAKKEHIVRATLESIAYQTKDVL
                     EAMQNDSKLKLKSLKVDGGASNNNFLMQFQSDILNVDIDRPKIVETTALGAAYLAGLS
                     VGFYIGRNEITSKWSVEKEFNPNMSEEKRCKLYKGWKKAVSRALSWEKEDELDI"
     gene            complement(87942..88571)
                     /locus_tag="KRH23_000082"
     CDS             complement(87942..88571)
                     /locus_tag="KRH23_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006813 - potassium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA C-terminal domain-containing protein"
                     /protein_id="HHS5223382.1"
                     /translation="MDKNYTMPIYQKIALDIANKIYTGEIQEDSVLFGRSVLAGKYNV
                     SPETIRRAVKILEDIGVVKSIKGKGVIVLSPDKASSFIKKYRDITNISSYKSTLYNLI
                     DTKSNLENEILDTINKILDYSNRLEIINPLVPVQFTINSNCKYIGQTAAQTKFWQNTG
                     ATIVAIKRGEELIISPGPYIEFLEGDILLVVGDQHIYNSIPMFLYENEK"
     gene            89159..89950
                     /locus_tag="KRH23_000083"
     CDS             89159..89950
                     /locus_tag="KRH23_000083"
                     /EC_number="3.5.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA];
                     GO_function: GO:0017168 - 5-oxoprolinase (ATP-hydrolyzing)
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LamB/YcsF family protein"
                     /protein_id="HHS5223383.1"
                     /translation="MYKVDLNSDLGESFGTYKIGLDEEVLKYISSANIACGFHAGDPS
                     HMEKTVQLAKKNGVKIGAHPGFLDLIGFGRREMKITKQEAKDYTKYQLGALMAFASSN
                     GCNIQHVKPHGALYNMAAKDKELAMGICEAIYEVDKDIILLGLYNSEMINSAKEIGLR
                     FANEVFADRAYDNNGFLVPRNVEGAVIHDTKHAIDRVVRMVKEGTVETLTGEVIHIKA
                     DSICVHGDNPKAIEFVKEIRKRFELEGIEVCPLENIEVCSSENIV"
     gene            89979..91199
                     /locus_tag="KRH23_000084"
     CDS             89979..91199
                     /locus_tag="KRH23_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NRAMP family divalent metal transporter"
                     /protein_id="HHS5223384.1"
                     /translation="MSTKNITDKTKNKKDVGALIGAAFIMATSAIGPGFLTQTAQFTQ
                     DFGPNFSFVILITTILFIGAQVNVWRVIGVSGLRGQDIANKIIPGLGYLVAFLVALGG
                     LAFNIGNVGGAALGMNVMFNMNMTLGTVLSGLIAIFVFMSKNSNSLVDKITKFLALGM
                     IIIVGYVAISNHPPVGEAVSRMVKPENPKGLIFPIITLLGGSVGGYITFAGGHRLIDG
                     GITGEENIKEITKSSLLGILVATMMRVLLFLAILAVVSKGLQLDPENPAASAFKFSAG
                     AIGYKFFGLVLWSAAITSVIGAAYTSVSFLKTLNPFIDKYEKYFIIAFIAISTLIMAF
                     IGKPATLLILAGALNGLILPITLGIMLIASKRKDIVGDYKHPTWLLIFGLIVVLISAY
                     TGITSLSSLGALFA"
     gene            91219..91914
                     /gene="pxpB"
                     /locus_tag="KRH23_000085"
     CDS             91219..91914
                     /gene="pxpB"
                     /locus_tag="KRH23_000085"
                     /EC_number="3.5.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0017168 - 5-oxoprolinase (ATP-hydrolyzing)
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-oxoprolinase subunit PxpB"
                     /protein_id="HHS5223385.1"
                     /translation="METRYLISGDKAVVAEFGNEISEDINKKVISFMRAIEISNLKGI
                     VTEMVPTYRSLMISYNPLEIDFDSLIGNLKKIEDNLESIVLPKPKIHEIPVCYDEVFG
                     IDIKNVASYNNLTVDEVIKIHTSREYLIYMLGFTPGFPYLGGMDERIATPRLEVPRTK
                     IYGGSVGIAGSQTGVYPIDSPGGWQIIGRTPLKLYDENREEQILLRAGDFIKFVPITL
                     DEFIEIEKNNLSI"
     gene            91944..92930
                     /locus_tag="KRH23_000086"
     CDS             91944..92930
                     /locus_tag="KRH23_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="biotin-dependent carboxyltransferase family
                     protein"
                     /protein_id="HHS5223386.1"
                     /translation="MGFKVELGGFQTLIQDRGRVGYGQYGVSGCGAMDEYAHRVGNIL
                     VGNSEDEASLEVLMLGPTITFDEYTQIAVTGGDLGAKINGKEIQNWRSYQINPGDVLS
                     FRGVKSGARAYVSIAGGIDVPLAMGSKSTYTRAKIGGFEGRALKKGDYINTFIQEKDF
                     TINKKLSSKYIPTYSSEIVLRIVKGPQFDAFSNGEVEKFLSNKYKVTNEIDRMGCRLD
                     GESIKHLNGADIISDGISYGAIQVPGHGKPIIMLSDRQTSGGYTKIGNVISVDLYKLA
                     QAKPNDVVKFELVDIYEAHRLLREQEDKIQDIYKSMKNIRVVKAKVLNDIAV"
     gene            complement(93144..93710)
                     /locus_tag="KRH23_000087"
     CDS             complement(93144..93710)
                     /locus_tag="KRH23_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHS5223387.1"
                     /translation="MLGEKMRNIRKSKKKTLSDVSKLTDLSISYISQIERDAIEPSLS
                     SLRKIAEVLDTPLYMFMDDNNTDDLVIRKEDRVMMKFPKSEMFYEIVSPMPTTEFTPS
                     ILFVEFELKPESEDAKDYIYHASEEIMVVTSGVVDICMGEKVVRLNPGDSTFIKANVP
                     HKIINPSKDTIARGYGVISPPIWPIKSK"
     gene            94062..95129
                     /locus_tag="KRH23_000088"
     CDS             94062..95129
                     /locus_tag="KRH23_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mandelate racemase/muconate lactonizing enzyme
                     family protein"
                     /protein_id="HHS5223388.1"
                     /translation="MKITDIKFEKLRIKLKKPVVVSFGVIEYGESVILKIETDEGYCG
                     FGEAAPLAAVTGEVLDNVLSVLLMFKKELIGKDPLDIETIHTIMDGIIIGNTSAKAAI
                     DIALYDIKGKIMNAPLYKVLGGFDSKVQTDITISIDKPEKMAVEALERVKEGFRILKL
                     KAGINPEDDIEAVKLIRKAVGESIRIRIDANQGWNINSSINTIKKLEEFNVDAIEQAL
                     PHWDLDGTAYIRNKSNTKIMIDESLHSPIDAIKAIKKNAVDTFNIKLMKSSGIYPAIK
                     INNIAEASGVNCMLGCMLETRIGITAAANLIASKKNITEADLDSFMFCEELEGISGGF
                     VMDGDIMNLVNKPGLGIEVNL"
     gene            95148..96308
                     /locus_tag="KRH23_000089"
     CDS             95148..96308
                     /locus_tag="KRH23_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF819 domain-containing protein"
                     /protein_id="HHS5223389.1"
                     /translation="MNTLFSNPGSILAVMTSMIALGFYLQRYKAIKSLGPALTIIIMG
                     IILSNLKVVPVSTELYGTISTYAIPVSMTIMLMSVDLKEMTKLSREPLIAIFVAVLTV
                     SIMAFLFGLVFAEKISEGWKVAGMFVGTYTGGSANLTAIGTGLNVSRQTLAAANAADY
                     VIGVPTLIFMFALPAILKNSKKFKKLWPYHVEESELEDCQNEEFMESKEWSIKDIAWM
                     LAIGFVVTEVSTILAGYFNSSFSSAARILLVTTISIIIAQLKPVKKLKGNLDLGLFVA
                     LFFLCTIGFSVDIKEFLGSTFTITLYCFSIIFASFVFHLGITRLLKIKYQYVILSIVG
                     AIADGPTSALVAASAKWNSLVSVAVVMGVIGGVLGNYAGISVAYAIKMSLGL"
     gene            96321..98417
                     /locus_tag="KRH23_000090"
     CDS             96321..98417
                     /locus_tag="KRH23_000090"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CocE/NonD family hydrolase"
                     /protein_id="HHS5223390.1"
                     /translation="MIKFKLYISGLYSGNVIFDGDLLIEKLNPFTNKVENLKPISKEE
                     NTYYLNLTKIDLKSLFNNFDVYTKSLVNTDKDTVINNLGETHSKLNEYIWVQRNKKFP
                     LDIIIVDNKIVGFICLSRETCTILIMDGYEEYTVLKEWEKTHKNEEIYSIRFGGNYMI
                     NMKDGIKLSTDVYLPDFVDSTKKAPTILMRTPYGKENDKEIYYKYVQRGYAVVIQDVR
                     GRNESEGKWEPMIHEREDGDSTINWIVSQEWSSGIVGMLGASYLGYVQWAAASSGNKH
                     LKALVSIVTSGSPFIDIPRKGGAFVSGMLAWAFMVSRNKVDRSKMVRDDWDDVLNIRP
                     IENIPVEALGYRIEFLEEWLKRVEKDEYWDLMDWHLQKDKINVPALVVSGWYDDNSMG
                     TTEALDVIKDYEKGKRKAILGPWMHNSNTLRDINGISLGNSSLRYDLDYNYLLWFDKY
                     LKGIENNIDTTAPVEYYSVGSNKWKTEENWPIINKIDKSMYLISDGNANTSLGNGRLV
                     FDNDLEEKYDSYIYNPKDPSVQLIDMSENEVGVPNNYKDLEKRSDMLCYTSDAFSEEF
                     TVTGDIKLEFFASSSAKDTDWVIKIMDVDLDGNSIKLADGILSARFRNSFYKSEFMEE
                     GEIYKFTIITSKISNTFKVGHKIRLDITSSAKNFIFQNSNTTEGYNSIEYIEAKNTIY
                     HGGKYPSKLILPIENK"
     gene            complement(98576..98920)
                     /locus_tag="KRH23_000091"
     CDS             complement(98576..98920)
                     /locus_tag="KRH23_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HHS5223391.1"
                     /translation="MEIKRYEGTGRMSRAVVHNNTVYLCGQTHAEGGVIEQTTEVLAK
                     IEDLLNKYGSDKQHLLSVTIYLRDMKDFEAMNSVWDAWVEKGFEPARACVEARLAREH
                     LLVEMSVVAATK"
     gene            99212..100102
                     /locus_tag="KRH23_000092"
     CDS             99212..100102
                     /locus_tag="KRH23_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HHS5223392.1"
                     /translation="MSSTIKSNRIKGIMFIIASALGFAMMSAFVKLAGDLPSFQKVFF
                     RNLVSAIIAFWLIIKHKGSLTGKKENLKVLLYRSIFGTLGVIFNYYAIDKLMLSDANM
                     LNKMSPFLVVIFCAIALKEKINVKQIGAIIIAFIGALFIIKPTFSVEVIPYLGGIAGA
                     VFAAMAYTCLRVLGDREDYYTIVFFFSVFSLVTVGPIAFAVYEPMTLMQLIYLLLGGV
                     FASLGQFGITLAYKYAPAKEISIFDYSNIIFSAILSIFLFNVYPDMLSVVGYLIVFSA
                     AFYMFLYNKKLDKLDKEKKK"
     gene            100320..101606
                     /locus_tag="KRH23_000093"
     CDS             100320..101606
                     /locus_tag="KRH23_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family protein"
                     /protein_id="HHS5223393.1"
                     /translation="MEKVKVAVIGAGNRGTYAYAPYIYENSDVCEIVAVAEPKKGRRE
                     LFTQKYNLDSKNVFETLEDFFKHDKMADAVIIATNDDRHYDVAKLALEKGYHVLLEKP
                     MSNSLDGLVHIDDLCDKYKDKIFMICHVLRYSPFYNKLKEIVESKKLGELVSIQYNEN
                     IGYWHFAHSFTRGNWRNSNETSPLILAKSCHDMDILLYLVGSRCKKISAFGSLKHLNN
                     QNASGEMAQNCLQCLVEKKCPYSAKRIYLEKDRSINRAVHINPTEENLLNILKTSPYG
                     RCVYRCDNNVVDNMVNILQFENGVTATFNLCAFTKENGRTIKLMFSHGEVGGDLNKNE
                     IRIKEFGKNEEIVMNPSNQQNMVEEYDRNLIAEFIKLVSNKELEKGRVAAKEAIQSHV
                     MAFAAEYSRVSDEVVYIEEFFDSAKQMTKEIEETIF"
     gene            complement(101695..102138)
                     /locus_tag="KRH23_000094"
     CDS             complement(101695..102138)
                     /locus_tag="KRH23_000094"
                     /inference="COORDINATES: protein motif:HMM:NF025547.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="regulatory YrvL family protein"
                     /protein_id="HHS5223394.1"
                     /translation="MIKISNKRRIPLGEFISVFLFFAVFFGITFCIFTVIGIGFLSFL
                     GFEYKSLGAVLIFFLIYFCITTPIDFLCTTILDIFRYVNKLPYSIYKLCEFIIDFILT
                     FLAMNIIDTFMDSVTIPLSTEILFALLSYLLSECMDFFDRDKKKP"
     gene            complement(102162..102956)
                     /locus_tag="KRH23_000095"
     CDS             complement(102162..102956)
                     /locus_tag="KRH23_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M55 family metallopeptidase"
                     /protein_id="HHS5223395.1"
                     /translation="MKLYLSADIEGTCGIVNWDETKLECEFSQHYRTQMSKEITAACD
                     GATQSGVHEILVKDAHDSGRNINPNILPENVKILRGWTKDPLVMMAGIDESFDACIFT
                     GYHSGATCNGNPLSHTMDIDYDYFKINDEIASEFTINAYIAAYYNVPVAFLSGDEMLC
                     ESAKKLNPNIVTVPVSKGIGNGSISIHPNLALKKIEKGVKKALSGDLSRHLIKLPDKF
                     KIEIKFREHYKAFKASFYPNMKKIDSQTVLFETEDYYEFLRMLLFI"
     gene            complement(103522..103998)
                     /locus_tag="KRH23_000096"
     CDS             complement(103522..103998)
                     /locus_tag="KRH23_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase"
                     /protein_id="HHS5223396.1"
                     /translation="MKEILINPIGKICIQGEEVFIKLDKKYVPALNELDDFSHLNVFW
                     WADGFDNPELRSILETPKPYKSGPDVIGIFATRSPIRPNPIALTAVQIINIDHENGII
                     KIPYIDANDNSPVIDLKPYTPSVDRVENPSVPKWCSHWPKSVEKSGEFNWEDEIEF"
     gene            complement(104099..105268)
                     /locus_tag="KRH23_000097"
     CDS             complement(104099..105268)
                     /locus_tag="KRH23_000097"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M20 metallopeptidase family protein"
                     /protein_id="HHS5223397.1"
                     /translation="MLNIKTLCHEINDWVINIRRDLHKTPELGLEEFQTKKKIIKYLN
                     EIGINYIEYKNHTGITAYINVSPNFETVAIRADIDALPITEELNYSYKSINIGKMHAC
                     GHDAHTAILLGTCNILFKLKDYLNVNVKFFFQPAEETIGGAQLMIEDGCLENPNVKYI
                     FGLHVNPNINKNLIELKYNTLNASTDTLQLTVHGSKCHGAYPHQGIDAIVISAHIITA
                     LQTIVSRNTNPTDSVVISLGKIEGGIKENIVCDKVVIRGTLRTLTPETREFSKKRIRE
                     ICDFTCKTFGGSISVEIEEGYPALINSNHLVDYVKQNAVELFGEENIILKDSPTLGAE
                     DFSYFLRHCEGAFYHLGCANREKNITSSLHTSTFDIDEDCLITGVMLHVKNVLSF"
     gene            105431..106294
                     /locus_tag="KRH23_000098"
     CDS             105431..106294
                     /locus_tag="KRH23_000098"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004180 - carboxypeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S66 peptidase family protein"
                     /protein_id="HHS5223398.1"
                     /translation="MLGIIAPSGPLRNTSLEEIKFNLESYGYEVKFSESCSLNYKGYL
                     AGNDDIRARDIEDMFLDKDVDIIMCLRGGYGTTRILDKINYDIIKQNPKPFIGFSDIT
                     GLNLAFYKNCGLLPYHGIMAANVGKWDKFTYKSLVNALEFKDELYLENPKEEKIYTVC
                     EGKAEGIIMGGNLSLIIATMGTKYEIDSKDKILFIEEIGEPQYKLDRMLTQLYSSGKL
                     EECNGIIFGDFKDCIEENDLMELLIEFANKVNKPSIYNLQSGHCIPMITIPLGRMCEL
                     DATEKIVKLKK"
     gene            106365..106958
                     /locus_tag="KRH23_000099"
     CDS             106365..106958
                     /locus_tag="KRH23_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3867 domain-containing protein"
                     /protein_id="HHS5223399.1"
                     /translation="MSDDRIIDFNELKNKVKDSDVDKFEQYIYNLYFSVMDGKMSMAE
                     FSRKIFDYMRDNNISQEKFMKIQKQFMERYGMDTEEVEKQLRNFGIDPSTAGFMSNNT
                     SSKVSTEDLESFKKSAGFYEKYGEKIQPKSCITTFIKNDLNDINVIIDQEKIMLCSDR
                     KINLMDSELNEFLLEYKNMFNKKIKVVMCETTNKYDY"
     gene            complement(107209..107844)
                     /locus_tag="KRH23_000100"
     CDS             complement(107209..107844)
                     /locus_tag="KRH23_000100"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isochorismatase family cysteine hydrolase"
                     /protein_id="HHS5223400.1"
                     /translation="MDNLLNELEALKSNLDNLPIEKIENYDLSKTALFIIDVNNGFAR
                     QGALYSPRVESLIKPIEMFTKKISNKLNRVIAFTDSHTPKSIELLSYPVHCLENDVES
                     ELVDELKSIENLQILPKNSTNGFFALENLDFDNIDNIIIVGDCTDICIYQFAITLKSY
                     FNQHNIEKNIVVPMNLVDTYDIPNVHPAEILNLVFFNSMIQNGVNVLKEIR"
     gene            complement(107924..108655)
                     /locus_tag="KRH23_000101"
     CDS             complement(107924..108655)
                     /locus_tag="KRH23_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HHS5223401.1"
                     /translation="MNIYAHRGFSGKYPENTILAFKKCLDMDIYGIELDVHRTKDGKI
                     VVIHDEKVDRTFNGHGFVKDFTLRKLKTLNSSFEGYQSNKECKIPTLEEVLILISPTD
                     LILNIELKTDKINYPNIEKDVLELILKYNMKNRVLISSFNSNSLKNFHKLDPSVKTGL
                     LCYLPINNVVNFAKFLGNSYLHPPLVLVNESLIELCHKNLLGVNVYTVNEEDDILHCL
                     KLNVDGIFTNYPDIASNLLHSKQYS"
     gene            108986..111175
                     /locus_tag="KRH23_000102"
     CDS             108986..111175
                     /locus_tag="KRH23_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid adenylation domain-containing
                     protein"
                     /protein_id="HHS5223402.1"
                     /translation="MYEVNLERAMNYWMDLLDDYTNIAKIPNDFFYKDCSDEVVDEVF
                     KMNIEKHERLIQYSKVNNISIDSIIETIYGLILQKYIYEDDVVFGKTMNIIPIRVRVR
                     QSEKFIDVVRKLKRQWSRSLEYGYYLLSDIENKNHLNTKLINTIFIAKSFDLSYDYDI
                     EKKGYDLSVIVYTKRALKIKIKYKPSIYKRETIRRILNQFDYIIEQIIEDNDILIEDL
                     EFVCKEEEKVLLEDFNNNQYEVPYDKSYVDLFREQVKVTPSNIAARDENRKLTYKELD
                     EVTDKLAGYLNHIGVESEDIVAVMLPRDINIIITAIGIMKSGGAFFPIDTSNPEERLN
                     YLLEDSNAKVVITTDELKSKVVNENTIVLDINDEEMFKLGYELTEKITSSNCAYTIST
                     SGSTGRPKTIAIEHKSLVNMCYYSVKSISATENDICGIYLSFSFDAVMKQLFPYLLVG
                     ASIDIMPEEAKFDEYTVNEYCEENDITILALPTAFARLFIQNCNNNSLRVVQTGGERL
                     KGYRKRNYELYNEYGPTEFTVVSTSFHVDREYGKIPIGKPIFNTYAYVLDKKNKLCPI
                     GAPGELCLSGIQISRGYLNKKGLTEQVFVENPYKTCEHNKLMYRTGDLVRWLDDGNLD
                     YIGRMDNQVKIDEFRIELYEIENIINNITEIKSVVCISRTNDDGDMYICAYYVIDEED
                     SGKINERTIREYLNEHLPPYMIPTIIMRIDKIPVTPIGKVNKRALPE"
     gene            111586..113514
                     /locus_tag="KRH23_000103"
     CDS             111586..113514
                     /locus_tag="KRH23_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0035673 - oligopeptide transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006857 - oligopeptide transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="OPT family oligopeptide transporter"
                     /protein_id="HHS5223403.1"
                     /translation="MNKKLPKGAYGEVSGKDYVPYITDKSRTGGNVAVLIIGIILAAI
                     FAASTTYSGMKAGLTVAAGIPGAIIGSAFVGAFARSKGILGKNLIQGMSSGGESVASG
                     FIFVLPAVILIGSQITFFEGLAVGVGGVLFGIGIAAIVHNYLIVEEHGKLMYPESMAI
                     SETLVASEAGGDSIKYMGIGFVISGFITVLTGSFLNVANNVMSLVGSKFYKWKFDIEV
                     NPLLLGIGFIVGLEVSLTMFAGSILSNFGIAPLIGYFTDMAKDGAMVWNNPAMPLNQM
                     DVGAISSSYVKYIGAGMMLCGGIIGAIKLIPTIIASIKETLKAKSSAGEGEEGSSIQM
                     ILLLGGVVIGFLAAFLISGNIVMAIIGAIISLLLSLLFVIVAGRLTGTIGTSNLPVSG
                     MTIASLVIVTLVFVIMGWTDLEANKSLLLFGSFIVVAIAIAGGYTQSQKVTYIIGGSK
                     NEMQRYFTIASIVGVIVVVGVILLLSDQLRATGDNVQFALPQANLMSTLTSGIMSGSL
                     PWVMIIVGVFMAIVLYALNLPIMTIAIGFYLPIATTSIILVGALIRLFVELVSKTEKE
                     KEVKVSNGISLSSGLVAGGSIIGLIGIILQVTGVVTPKVPSGFAATNSMAIALLVVLV
                     VLTALPIVLSKVKNNEQE"
     gene            113501..113848
                     /locus_tag="KRH23_000104"
     CDS             113501..113848
                     /locus_tag="KRH23_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PqqD family protein"
                     /protein_id="HHS5223404.1"
                     /translation="MSKSNDVLDIVFKITDGLEYEVAENSVVTILEKQDHKIQKFFRK
                     LKARIPKYKKIELDEYSSFVFLQIDGQRTVREIGKNLEAKYGEESHPLYERLLVFLNH
                     IEVNCHYIERLDI"
     gene            complement(114090..116045)
                     /locus_tag="KRH23_000105"
     CDS             complement(114090..116045)
                     /locus_tag="KRH23_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HHS5223405.1"
                     /translation="MKNNRLEIKVNYMNLMTLENISKSYSEKKLLENISLGINEGEKI
                     GLIGVNGTGKSTLLKIIAGVEESETGNITKTNGIRIEYLPQNPTYNENSTVLEQVFNG
                     TSEELKLLGEYQEILEKLNSNFTEELNKKLLSVHEKIDALNLWDLESEAKSVLTKLGI
                     NDFNQKIAELSGGQRKRVSLASALITPCEFLILDEPTNHLDNDTIDWLEEYLNSRKGS
                     LLMITHDRYFLDRVTNRIIELDKGRLFSYDGNYSIFLEKKMERLSLEASIEDKRQNLI
                     RTELAWVRRGAQARSTKQKARLQRFDELINRYSFKPDENLDISVASSRLGNKIIEIHN
                     ISKSFEENTVIDNLEYTLTRTDRIGIIGKNGMGKSTLINILNGEIEPDSGYISIGETV
                     KIGCFSQDDSHMNIDMRAIDYVKEASDYIETSDGTRITASQMCERFLFNGTMQYTLIG
                     KLSGGERRRLHLLKILMTAPNVLLLDEPTNDLDIETLKILEEYLDEFKGVVVTVSHDR
                     YFLDRICNKIFAYEGNGKIHIYTGNYSDYLIYREIQGIEFEESKKESVKKDDSTTLKK
                     EKPKNDKKLKFSYNEQREFENIDSDIEKLESKIATLDESTAKFSTDFTKLQEILDEKS
                     KLEKELEYKYERWEYLNNLADEIANNK"
     gene            complement(116035..116817)
                     /locus_tag="KRH23_000106"
     CDS             complement(116035..116817)
                     /locus_tag="KRH23_000106"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HHS5223406.1"
                     /translation="MSKKSKRRKINKLKLTIVITVLFLALLSIYEILFSNPNKKGNIK
                     SQETMQNKNNTTDDSKNNQSSTKKQEDNNIKPTFSYSSIPDNIKNKMIGKSMPTDEPI
                     SFDSLSYLKLTYYGFDEKTHQGEMIVNSELAPEVVDIFKELYEKKYPIEKIKLIDDYD
                     AVDEKSMSDNNTSSFCYRTIAGTNVVSNHGKGRAIDINPLQNPQVSGNDVTPKVSTVY
                     ADRSSTKFGMIKKGDDCYNAFVSRGWSWGGYWKNPDYQHFEK"
     gene            complement(116900..118348)
                     /gene="ddlR"
                     /locus_tag="KRH23_000107"
     CDS             complement(116900..118348)
                     /gene="ddlR"
                     /locus_tag="KRH23_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator DdlR"
                     /protein_id="HHS5223407.1"
                     /translation="MIFSNLKLNDNEPIYIQLKNYISDMISKGLIPDNSKLPSTRELS
                     QLLQVSRNSVVLTYEELKSEGLIYSISGKGTFVKSKNKSSNTTWSLNWDCLENTYSKK
                     ANELDIIKSEIPWSSDLISFKSISPDGDLFDMEELKKSFLNRISLEGHKLLNYGYAQG
                     YKPLIDYLLEYMTNKGADISNKDILITNGFTEGFDIIMSSFTQEKDYIICENPTHNTA
                     IKIMKSHNLNILGVDINEDGLDFNMLEDNLVKYKNKIKFAYITPSYHNPTGIVMTPEN
                     RYKFYNLMKKYNIAIIEDGFNEELLYNSSHIFPICSLDNMNNGVVYIGSFSKILFPGM
                     RIGWIFADKKVINKLESVKRCRNIHVSFLDQGILFDYLSNGGFEKYIKKIRKFYGDKF
                     NFAYKCIKKYIKTEYILGDGGLHIFIKLKNIDTRVLLEKCYEKNVIFMPGDLFFTDNS
                     GFDTLRLGFSRLSFEDIEIGIKIIGETINEMF"
     gene            complement(118372..119271)
                     /locus_tag="KRH23_000108"
     CDS             complement(118372..119271)
                     /locus_tag="KRH23_000108"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008716 - D-alanine-D-alanine ligase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HHS5223408.1"
                     /translation="MKIAVIMGGISSEREVSLNSGKEIYNNLDKNKYEVVKVIIDDKK
                     DIFTKIPEDIDFAILALHGKFGEDGCIQSILETMDILYSGCGPLCSGMCMDKNITKKM
                     LRDSNLPTAPWVLVKSVDEIDYDEIDNIGYPVFIKPNSGGSSVATFFIHSKDEVEEAV
                     RKGLEVDEFVMIEKYIPGGEYTSFILNGEVFPTISIKSDSGFFDYEAKYSVEKGAKEE
                     VVYLDEELQKRVNEISETCWKIFNCKAYVRVDMIISEGIPYVLELNTLPGMTQTSLIP
                     RSAAARGIKYSELLDKLIEYSLN"
     gene            119529..120785
                     /locus_tag="KRH23_000109"
     CDS             119529..120785
                     /locus_tag="KRH23_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HHS5223409.1"
                     /translation="MKAEIISVGTEILLGDIVNTNSQFLAKELASLGIEVYHQSTVGD
                     NKQRLLECFDESLKRSDFVITTGGLGPTGDDMTKETAAEYFGQKLELHKPSLEVLESF
                     FVKTGKKMAENNMKQVYFPKDAIVLKNNNGTAPGAILEKDGKFIIVLPGPPREMKAMF
                     NESVKPYLQQFTNEMLVSKTLRLYGIGESNLELEILDIINEQTNPTVALYAKELEVTI
                     RITAKAENEREAFKLIKPVEEKIKSRVGKYVYTEGDISISEGETALEDAVSKLLVEKN
                     LTIAVAESCTGGLVSSSLINYPGISSVFLEGCVTYSNDSKMKRLGVKRETLEEFGAVS
                     EQTAIEMAEGVAKGLKANIGISTTGVAGPSGGTKEKPVGLVYTAIYINGKTIVKKNIF
                     NGDRRKIRLRATRDLLNELRIQLEKL"
     gene            120842..121621
                     /locus_tag="KRH23_000110"
     CDS             120842..121621
                     /locus_tag="KRH23_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HHS5223410.1"
                     /translation="MIKHIFCDLDGTLYENGTITKEDIVAIEEIEKKGVQFNVATGRI
                     FKQAHNIIKDSLDMNGYYVCENGSFIYDKDYNVIFKRTIDDNLVKKVIDRFESSDAQL
                     YFKYKGDVIVGSDTTAFRHYSSDFIVDPDFEKRSSFDNLIGNIGVCSENLEELSRIEL
                     YLKSEFSEVLEIYFSGTYTLNIVPKSVSKRGSIEHVIKTLNVSPDEVATIGDSPNDIC
                     MLEGFKYSFAMSKAREDVKQSANYVVDSVKSAIDVIMEINS"
     gene            complement(121725..122309)
                     /locus_tag="KRH23_000111"
     CDS             complement(121725..122309)
                     /locus_tag="KRH23_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc dependent phospholipase C family protein"
                     /protein_id="HHS5223411.1"
                     /translation="MLMNTHFIMAKSILDNIDENKTFFISEKNFIYGNIKPDAFSKYK
                     LKKHYLDESFNMIVSKINYLCSLNIDSLSKYFSVSRLSQELGVICHFLCDFFCVAHSE
                     RWEFKHSLNKHVTYERELGAFAKDVDLSKIKCGTINSSFEKFFTKLYSDYKKKTDYMN
                     DLKFSAYTCNSVINYILDSILSNTIKSYHIANCG"
     gene            complement(122509..123951)
                     /locus_tag="KRH23_000112"
     CDS             complement(122509..123951)
                     /locus_tag="KRH23_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54 interaction domain-containing protein"
                     /protein_id="HHS5223412.1"
                     /translation="MNLNLKLDLEFYQKILEASHDEICVSDDKGIIIYCNKAFEENYG
                     LKKEDILGKNVSFLEDSGYSTKSPIPIVLKTKTKFSLEQDTQTGKKLIITATPIFDEN
                     GNLEFTVENCRDITELNNIKNKLEDTKKQVKKYKSEVETLYRTALRIEDTVIMDGIVM
                     RPIINTVNHVSKTDVSVLLLGESGTGKSSLARYIHHNSNRSNGPFITINCATISPQLL
                     ESELFGYTSGAFTGASTKGKVGLVELANGGTLFLDEIGDIPQNLQAKFLQLIQDRTFT
                     PVGSLKNKKVDIRIISATNVDLVSKVKEKKFREDLYYRLNVIEIKLPPLRERRDNLVE
                     IIKYYFNRYSSDFNLNKTISKEAMDAIANYRFPGNIRELQNIIQKILLTCTDNHITID
                     DLPNILTKNIHITNNGNKTHISQINKVIISDSKSTNYKNKNFDTLIKEYEKNIILDAY
                     EKFGSSYKVAKHLEISQSKANRLIRKYTNT"
     gene            124268..125212
                     /locus_tag="KRH23_000113"
     CDS             124268..125212
                     /locus_tag="KRH23_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HHS5223413.1"
                     /translation="MGEKSKGYVFIAIAGLLWATLGLFGKFLMGNGLTSEQVAFTRLF
                     FGFIVLGVYSSIRTPQILKISKKGIIYSVIIGIICQAMFNLCYFKAIDIAGVSIAAVL
                     LYTSPLFLAIFSKVCYKENITRSKLFSLILCFIGAIMAVTGGRLDFQGLNAFGLLLGV
                     LSAIAYALMPTISKNALKEFSSSTILVYSFLFGAIFMIPSSRPWEILNYAKDLDVLSC
                     MLMLGIVPAALAYIFYAAGISKGVELSVAGVVASVELVGSVIIGCTILGESFSLGKLF
                     GVMLMLISAVVALNLSYDEIRIFYKSNKLKQIEKTESI"
     gene            complement(125477..126412)
                     /locus_tag="KRH23_000114"
     CDS             complement(125477..126412)
                     /locus_tag="KRH23_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893027.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HHS5223414.1"
                     /translation="MDKFKYAFDNKRYHTWNYYLRNTFGEKVFKVSINAGFTCPNIDG
                     SLGYGGCTYCSKEGSGDFAGNPKDNLISQFYNIKEMMLKKWPHAKYIGYFQAYTNTYA
                     PLEVLKEKYETILELEDVIGLSISTRPDCLPDDVVEYLSELNKRTNLWVELGLQTIHD
                     STSKIINRGHDYKTFVEGVEKLKSKNIKVVVHIINGLPGEDYNMMMETAKAVGKMGVD
                     GIKIHLLHVIKDTPMEKMLQNGMLTLMEQDEYINLVCDQLEILPETMIIHRLTGDGKR
                     DELVGPIWSLKKWEILNQIDDTLKARNSYQGCKFV"
     gene            complement(126531..127079)
                     /locus_tag="KRH23_000115"
     CDS             complement(126531..127079)
                     /locus_tag="KRH23_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014466364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF308 domain-containing protein"
                     /protein_id="HHS5223415.1"
                     /translation="MYTNFNIDFNNFNKKENAIKFMLMGVLLIILGLLCLTFKTLGIK
                     LISWTFGIALLFFAYLNLKNINELKRYATKEEIKPSINIQWVLIIACILLFVFPQKIQ
                     SIFSLFLGFYLIFNQLVALVNSKNNPYSKFTTWNIVKILFGICLILSPLFLSRFIVSI
                     MSFFIILFGLVLFFSGNTARKY"
     gene            127231..127659
                     /locus_tag="KRH23_000116"
     CDS             127231..127659
                     /locus_tag="KRH23_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HHS5223416.1"
                     /translation="MTKLWAIIFALLAGGSTALEAFINGELGKSTTALVATFISLTVG
                     AIFFLASIIVTGDLKCLVSINGFNYKLLLGGVFGGLIIYFTVKAIPNLGVSNTLILTL
                     VSQVLVGFFIDSVILGQETMHLYKYVGVILLILGTFFIVN"
     gene            127726..128394
                     /locus_tag="KRH23_000117"
     CDS             127726..128394
                     /locus_tag="KRH23_000117"
                     /EC_number="6.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphthine--ammonia ligase"
                     /protein_id="HHS5223417.1"
                     /translation="MKEVLKLADEKFVMSFSGGKDSILALNRMLKKGYKPVALLTTIS
                     EEHGKSWTHNLEYNMLKQVSSNIGLPLLVAECGVEGYEESFERALIKAKNMGATICAY
                     GDIDIESHRKWDTDRCEAVGMKVDLPLWQESREDLVYEFIDSGFCSVVTKVNLKHLGE
                     EFLGKKLTRELVEKIKNAGADPCGEHGEYHTFVVDGPIFKKPVEYEVKGTLIKDGYGY
                     LEIK"
     gene            complement(128512..129867)
                     /locus_tag="KRH23_000118"
     CDS             complement(128512..129867)
                     /locus_tag="KRH23_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA];
                     GO_function: GO:0042910 - xenobiotic transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006855 - xenobiotic transmembrane
                     transport [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HHS5223418.1"
                     /translation="MDTKISINENMSLGKRFFKYLAPSVVAMWVFSLYTMVDGIFVSK
                     GVGELALAAVNISMPFINFIFAVSLLFSTGASTIIAIYLGKKDIKSANEVFSFNLVSI
                     IILSIIILAITFFNLDRLALFLGATESTIGMVKDYLGIIIFFNGFFIVSYSLEVIIKT
                     DGFPILATVGVIISALTNIILDYLFVIEFGWGVKGAGIATGLSQVFSTIFFLIHFLRK
                     NSTLNFSKFRIDFKTLRKIVFIGFPDSTTELSCGIVVLLFNLSLTKYIGENALIYYSV
                     INYINTLVLMTMMGITQGMQPLTSFYYGAGNIDNVKKLLKMGIKATIIASVAVFAICM
                     AFSGPIVSLFIHPEETMLFNEGVRVFKIFSISFLLVGINVIISGFFVSVEKPSISTVI
                     SLGRGLVIVVLSLISMILIFGGQGIWMTTIVSEFICLILSLVFLKKNFSTLDSNLNKV
                     A"
     gene            130954..131106
                     /locus_tag="KRH23_000119"
     CDS             130954..131106
                     /locus_tag="KRH23_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA];
                     GO_function: GO:0090729 - toxin activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin"
                     /protein_id="HHS5223419.1"
                     /translation="MDNFLQGVLASLVASLIVYLNSKLFKKVKSHSGRSDFSFELKIK
                     FKKNKH"
     repeat_region   131386..131807
                     /inference="COORDINATES: alignment:CRISPRCasFinder:4.3.2"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=131386..131414
                     /rpt_unit_seq="gttttatattaactaagtggtatgtaaat"
     gene            complement(132199..133932)
                     /locus_tag="KRH23_000120"
     CDS             complement(132199..133932)
                     /locus_tag="KRH23_000120"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0052621 - diguanylate cyclase activity
                     [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor domain-containing diguanylate cyclase"
                     /protein_id="HHS5223420.1"
                     /translation="MSILLKKAPKLAKHIITSFYINRDINEVLKYLCENVTWIGPGEQ
                     EFLTSFNEIKNYFYAGQDEIPSCDINNDIFETVSEDENRCMVLGRYTVRTKENAQMIL
                     EVNQRCTFEIIEDRGKLLIKHMHISNPYGEMQLDEYFPTKIGTQSYDYLQRLLKEKTE
                     VIEMITNNINGGLKGSNDDSTYSFFYVNEGLPKILGYTYDEFMEMSGGSAVGAVYPPD
                     LPKALEDCERCFAKGPTYSSEYRIRKKDGTLMWVLDSGMKSLNSDGIVKINSIITDIT
                     QLKNIESELKLERERYRIALQNITDIMFEYDIENDTLIKYQRVEIDKKIELENFETKN
                     YSKLLESGKIIHLDDIGKLLEVLHGNLRETIEIRQVNSLTKNEWRWIRVQCSVIYDSD
                     HNPIKTIGVLKDITEDKSKLESLINQAQRDPLTQLYNQRVSQNLIEEYLCSSDSKNND
                     ALLVIDIDDFKTVNDTFGHLEGNEVLVAVSKILLHNTHDKDIVARIGGDEFTIFIKSL
                     TKDLIIKITNDILNDASKIKVKDNHKITLSIGIAFTDDSTKLYKDLFSKADKALYLSK
                     ADGKNCYSTYE"
     gene            complement(134172..135017)
                     /gene="dccA"
                     /locus_tag="KRH23_000121"
     CDS             complement(134172..135017)
                     /gene="dccA"
                     /locus_tag="KRH23_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="c-di-GMP diguanylate cyclase DccA"
                     /protein_id="HHS5223421.1"
                     /translation="MFKEIFLRTFPGFLIIRDSNYRIIFINDNLKNLIKSYMQDNPLG
                     MTNIEIAKKLPDNIAKFFTDSHNIQLDWEKNYPYDKISNWILEFKKDTTSYWNVLEYK
                     VDVDEKTYIITMANDITKLYEENKRNLHYSITDPLTGAYNRKYLNDRFDIFIGDYIVL
                     IDLDNFKMINDYEGHNVGDKILCDFVSLLNKELINSTSIIKLGGDEFIVIFSSDVDKN
                     YVYSQLEALRENFLKVFSKYKYLSFSYGVDTVKRNLKLTIVELDKKMYKNKEKNKKKF
                     DKNDY"
     gene            complement(135048..137282)
                     /locus_tag="KRH23_000122"
     CDS             complement(135048..137282)
                     /locus_tag="KRH23_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HHS5223422.1"
                     /translation="MQNHNYIKMLNKKVEVLSKELDSRNFKLKTLNEIDFFSKIPNRE
                     FMYQHIDDCISKNIHIGIMLLNIDNFKLFNDIYGYLVGENLLITLTQNLLHFIPESKG
                     IVAYLKGEGFLIVLPNVSNKELNNMGATIIESARELKIRLPNEKEIYSNVTFSIGSTI
                     WNGEPNMNTLMLFNQVYSALKKAKSEGKNRYILFDFKDNSFYNKLENDKEFLSEISHV
                     LQTKQIEVFYQPLYNIKNNTIVGCEALARWRHPIKGLLTPDKFIPLFEQFGLITELDL
                     HLFEENCKNIRRWIDNNDVFVPICCNFSRLHFFNPNFPSMLKGITEKYSVSTSNFSIE
                     ITENILIENTNTIIQQLAELRSYGFSVSMDDFGSGYSSFGMLQNLPFDIIKIDRIFLS
                     HNLNDFKNTTILYSIINIARALGMLTVCEGVETEQHVEFIKSINCDIAQGYYYAKPME
                     CKEFEKLLSKENNSEKMFIKYSDIGKSLIEKIFDGFFIMQDMKKLRANVTEDIQWFDF
                     YNKTEITSFPKVIEHFEKHIKGKKFSILYKSITPHNTESDSLLISGEAVLSDEAAEHQ
                     KYSNFYFSANCIISENKLLLAKLHLDLIKTAGYINEFESYSIPKMTNTHLDESNILSQ
                     FYSMLPVGIIRYDLFGDMIITYMNEEMFDIIGYTKEQFFGEMGGNLRAIVHPDDLDFV
                     YKKSLDMIDTNKIEPFLYRFIKRDGQIVTVMYTQCNLSAIDGRSIAQGMYVDVNKIKN
                     LTKI"
     gene            138066..138875
                     /locus_tag="KRH23_000123"
     CDS             138066..138875
                     /locus_tag="KRH23_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HHS5223423.1"
                     /translation="MKDYYKIGEISKIYGIGRDSLMYYEEIGILRPVRDINGYRMYNI
                     SDIWKLNLIKEFRSLNFPMKKIKEYLDDRSIESTKNILNEELDLIDKKIAEFISHKEN
                     IIKRLSSIESVIQNTKIDEIEVVYIEKRKALELNADIKRDEDFDFLIQKLQKEYEDRF
                     NILGNNNIGSAFSTEAINKGIFNEFKSVFCFLESNEKVYNIVFDEGYYVTLNYTGSNS
                     NNKIYMEKVFKFIEENNYKIIADPIEIYKIDIHETGIVEEFVTEIQVPITK"
     gene            139020..139259
                     /locus_tag="KRH23_000124"
     CDS             139020..139259
                     /locus_tag="KRH23_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5223424.1"
                     /translation="MKCSNCGSVNIEKGILTTGGIYAETIGLKYRGDGKLDKVINKTF
                     PVQSTIYSDLCLDCGEIVRTYIKDNTDRNWCKDKK"
     gene            complement(139446..139622)
                     /locus_tag="KRH23_000125"
     CDS             complement(139446..139622)
                     /locus_tag="KRH23_000125"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5223425.1"
                     /translation="MFRDEMDKCTHMLTAYISSLYDYCDFIDTQLDDFILEYGENVVE
                     SCLHQVMVLVSKYN"
     regulatory      complement(139676..139772)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            complement(140127..140801)
                     /locus_tag="KRH23_000126"
     CDS             complement(140127..140801)
                     /locus_tag="KRH23_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HHS5223426.1"
                     /translation="MNHHILIQFEYIARIITAGFCGALIGYERKNRLKEAGIRTHFIV
                     ALASALIIIVSKYGFNDIVGTPGIGLDPARVAAQVVSGIGFLGAGLIFIRNQSVSGLT
                     TAAGIWATAGTGLAIGSGLYLVGIVSSIIIVIVQITLHRDRKWMKLPTAEQVSLKISN
                     STDSIEYIEGKFKKSNIEIINMNIKRLDGDWLEVVIYTKLPKGYKKTNLLKLFSDNPL
                     IETLEI"
     gene            complement(141289..142482)
                     /locus_tag="KRH23_000127"
     CDS             complement(141289..142482)
                     /locus_tag="KRH23_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005336078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HHS5223427.1"
                     /translation="MKEKRRDSKGRILHTGESQRTDGKYLYKYVDAFGNTKYVYAWRL
                     TPTDPTPKGKREKPSLRELEQQIRRDIEDGIDSTGKKMTLCQLYTKQNAQRANVKKST
                     QKQREQLMRLLKEDKLGARSIDTIKPSDAKEWALRMKDKGFSYNTINNHKRSLKASFY
                     IAIQDDCVRKNPFDFKLSEVLENDTKEKVALTEEQEQVLLSFIKTDNVYHKHYDDVLI
                     LLKTGLRISELCGLTVADIDFKNEVVSIDHQLLKSKEQGYYIETPKTKSGTRQVPLSR
                     ETIQAFQRVMKKRPKAEPFVIDGRGNFLFVNQKGKPKVAIDYNALFVRMVKKYNKQHK
                     DNPLPHITPHTLRHTFCTRLASKNMNPKDLQYIMGHSNISITMNWYAHASIDTAKSEV
                     QRLIA"
     gene            complement(142561..142764)
                     /locus_tag="KRH23_000128"
     CDS             complement(142561..142764)
                     /locus_tag="KRH23_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HHS5223428.1"
                     /translation="MNNNDIPVWEKYTLTIEEASKYFRIGENKLRRLAEENKDAGWLI
                     MNGNHIQIKRRQFEQVIDKLDAI"
     gene            complement(142764..143825)
                     /locus_tag="KRH23_000129"
     CDS             complement(142764..143825)
                     /locus_tag="KRH23_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009320105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HHS5223429.1"
                     /translation="MDYISIVFETATAEDVIMHILGLPTDIFNVYPASVKYKTYQARW
                     QIGDIYVSGDARKTEDNPQGLGCYLVMTGRGCDDIFRILDSRNYTFGDMFRRCERRYG
                     VDNFHFTRLDIAIDDKKEKPFFTIEQIKKKCEKEEFISNSEGYHFDESKFDDFDTAKT
                     VYIGAGKSGLSYRFYDKDKEVCSKHNKTLDEVGSWKRTEMQLRDDKAHAFAMTFKDRP
                     LELGELAFGLLANNLRFVVPNRNESNKSRWKTCRFWERFLGAVEVLKLQVPKQQNSLE
                     ETQQWLTEGGVISAVKSFYFLEEHDALGGLEKVGTMLDKARYSNSLSSKLTAHLQRIN
                     RTDLIPYIQYDTKHGKGGI"
     gene            144345..144980
                     /locus_tag="KRH23_000130"
     CDS             144345..144980
                     /locus_tag="KRH23_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHS5223430.1"
                     /translation="MEHYEKKISFLGENIQTIRKHRGMKQQELADKIGINMQSLSKIE
                     RGVNYPTFDTLEKIMDVLGVTPNELLSGEWKYVNQAEKEVCQFLRIEERLNAELKHGH
                     YDNFFDSEEEWLEYELEKLREYITDYINGTSIEASDLYPIKEFIQHLKFQKLLDRYDD
                     LYSMDMFGESIEGHKYRTPYQVVKMINPNSKEDMELLREVLKNNHFDDEDE"
     gene            145282..145944
                     /locus_tag="KRH23_000131"
     CDS             145282..145944
                     /locus_tag="KRH23_000131"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: protein motif:HMM:NF015123.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HHS5223431.1"
                     /translation="MTIVHSRDIILVKGVDYMNITKQKSQKTFDKQAADYDTNIQGEH
                     ARKLYKPIIENLKNKNIHSILDLGCGTGALLKEIKELNIAEQLFGIDISPNMLEIAKN
                     KLGNDATLILGDSERLPFEDSSFDAIVCNDSFHHYPQPDIVEKEVSRCLKQNGVFIIG
                     DCWQPIGARQIMNYYMKHSNSGDVKIYSKKEMLLLLSKDFHEIEWKSFGTRSCLIIAY
                     NN"
     gene            145968..146528
                     /locus_tag="KRH23_000132"
     CDS             145968..146528
                     /locus_tag="KRH23_000132"
                     /inference="COORDINATES: protein motif:HMM:NF012655.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HHS5223432.1"
                     /translation="MRISKEPEERKQEILETAIKLFSVNGFEKTSISDIAKEIGIAQG
                     LCYRYFPSKDVLFQSAINEYSNILVANMTKNINIKKDSLKDILRKMILFAEQEDDTYY
                     PVFHNNQNKNFHNLLTLNVCEKLFPIVSEIIERANYTNEIQVNDVEMYASFCIYGQLG
                     IILNTDISIKEKSLRIKAFFRDLFRL"
     gene            146604..147989
                     /locus_tag="KRH23_000133"
     CDS             146604..147989
                     /locus_tag="KRH23_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008728838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HHS5223433.1"
                     /translation="MNKNIDFVNGNTKKCLLEMTVPMIIAMFLNMAYNLVDSLWIGNL
                     LGEQAYAALTNSTPIILILTSIGMGATNGLAILLSQVIGAKNEQKKKNIIVTSFFVSI
                     ILSVFMTIVLEIFLEPILIVLNTPTEIFDMAKNYLSIYALGYVAVYLYLYFTAILRSF
                     GNTMFQAIAMLVSTLLNAILDPIFINIIGFHGAAIATLISQIICLAFMCIYIYRKKLF
                     NLSLSDFDTTEIMPFIKNAVPSVIQQSIPAISTTFLTAIVSTYSISAIAGYGVAGKLE
                     MILFYPAMALNMVLTSIVGQCIGAQRIDRAKNYLKLALKYGIVVSSVLSAVVIFFSKQ
                     LAKLFVSNEAVTNVVSHYFLIVSIGYVLYTITSCYLGTLNGIGKPAKSMVLMIFYYII
                     IRIPFAYLLSWLAENLNGVWIAILISHIVACIITILTSNQIIKRLYGKLYDRTKKARY
                     KSIESNCCGKF"
     gene            148181..148600
                     /locus_tag="KRH23_000134"
     CDS             148181..148600
                     /locus_tag="KRH23_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004610571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HHS5223434.1"
                     /translation="MNTSSFEHIVRIQFNALMMTVIKCTVKNRNRQFARRSKREVLFC
                     ELSDTKNVECVTKDNYSCDYISFEVLNFTIQISNEKLAVALYKLSNKERDVILLRYFQ
                     SMSDQEIAELYHVSRSAIYRRRSNGLKKLKTVLKERN"
     gene            148605..148844
                     /locus_tag="KRH23_000135"
     CDS             148605..148844
                     /locus_tag="KRH23_000135"
                     /inference="COORDINATES: protein motif:HMM:NF024059.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHS5223435.1"
                     /translation="MKKEYGYPTLKVICQASAGNETAIREILKFYDAYICKLCLRPFY
                     HSESGKIIMQVDEELKGQIHTEMMKAILKFEIRVK"
     gene            complement(148997..149491)
                     /locus_tag="KRH23_000136"
     CDS             complement(148997..149491)
                     /locus_tag="KRH23_000136"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase family protein"
                     /protein_id="HHS5223436.1"
                     /translation="MSIALILIDIQNDYFKNGKCELFQSEETAENAKKILLFFRKNNL
                     PVIHIQHISTDKTASFFLPNTHGSEINKIVFPLDNEEIIIKHTPDSFFETDLQSILEK
                     KNITNLVICGMMSHMCIDTSVRTAKKLRYDITLISDACTTKNLSWNNIEINANFISDF
                     RLSA"
     gene            complement(149569..149934)
                     /locus_tag="KRH23_000137"
     CDS             complement(149569..149934)
                     /locus_tag="KRH23_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HHS5223437.1"
                     /translation="MKIRAEYTCPLEIVHDIIKGKWKTILIFELRQSNKTFSELQHNI
                     YGINQKMLIQQLKELRDFGIIDKISSAGYPLHVEYFLTNRGKKMLKAVEIMQEIGIEY
                     MLEHGQQEILDNKGICYNK"
     gene            150165..150299
                     /locus_tag="KRH23_000138"
     CDS             150165..150299
                     /locus_tag="KRH23_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5223438.1"
                     /translation="MNISRKAMKIIELAQKIANKRGISVEEAWSEAVTEYKNKYEHIA
                     "
     gene            150399..151184
                     /locus_tag="KRH23_000139"
     CDS             150399..151184
                     /locus_tag="KRH23_000139"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HHS5223439.1"
                     /translation="MIVKIDNTLEKEFWQYVSHEESLNLFIIGYVENYGFSSQYQDIW
                     SQVEDGNITSIILKNKSTLIIYSFKNNFNIGEMKNHIKDLDVESISGKKCVIDRLISK
                     YKDFYEKLDNKFCVLKEIKEIDFSNMKEYKIENAQEKDIDEIGKLLNRSDYKVSKNYI
                     EERKVHLKEGNVRAYFIRNDDTMISTVSTGMETSFLAMVVSVSTDKRYRGKGLASYMV
                     YNLSKELLLEGKVPCLFYNNDVAGKIYHNIGYKEINEWTILFK"
     gene            complement(151281..152105)
                     /gene="pdaA"
                     /locus_tag="KRH23_000140"
     CDS             complement(151281..152105)
                     /gene="pdaA"
                     /locus_tag="KRH23_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="delta-lactam-biosynthetic de-N-acetylase"
                     /protein_id="HHS5223440.1"
                     /translation="MKKDSLKKYIMIGAFALILFGIASINFKSLDKTKTQISSPTLDT
                     HEYDWYFNPREDGKQPSPIKEADFFKKYGAYYVGNPNEKVIYLSFDAGYESGNTPKLL
                     DTLKKHNAKAQFFVVESYIKSNPELIKRMEKEGHLVCNHSKSHPSMAGITDFEKFKEE
                     ITSVEKAYKDVTGKEMPKYFRPPMGKFSEQSLKYTQDLGYKSIFWSFAYVDWYEKKQP
                     THEFAKNKIYSRTHPGAIVLLHPNSSTNTEILDEVLTHWEKEGYKLKTLDYLNNKK"
     gene            152326..155445
                     /locus_tag="KRH23_000141"
     CDS             152326..155445
                     /locus_tag="KRH23_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016818 - hydrolase activity, acting on
                     acid anhydrides, in phosphorus-containing anhydrides
                     [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helicase C-terminal domain-containing protein"
                     /protein_id="HHS5223441.1"
                     /translation="MDNIISVLNDVVFLDIEVSGLDCLNSEILEVGAVKVKDWKIYTY
                     ESLIKNKFEVPIEVFSVCKNLDKNDLEIANEIELVEDRLVNFVEDSFIICHDLSLKKK
                     FLEYHMPKLKNKFIDLIELAVILEPYHKDYSLEYLKNTLTNCNSKVENRALSDAIDII
                     NIVNCLLVKFNNYEKTTLEPLSFKINSYLKKFNLPTWEWSKFLEEANYDLSNNINIKK
                     EYNIFDSKEEKKKERETLKILNEEEKNYEELLKYKTIWENKEGFTYEYRPGQYELTKT
                     IRELFRNSEDEEKIACIEAPTGIGKSVGYLLPAILEARINKKRLLISTDTKELQIQLI
                     NKDIPNVLDSLGLNGKVSYGYIKGKNNYICIDRLEAYIDDYESQNPTKGEILSLIFLK
                     RLVEGGKYGDIEEINYLVFDNFKEISTHLRNVSCDPNMCRPKKCKKDCLYKNRIEELK
                     EEHITVVNHSLLAKWPYKDEKPLENIIVDEAHNLTEKGYDFFSSIINSKSLRYLLQEI
                     YPYEFIQNSSFIYKKYSRNMRKIKAFDKFYNVLKIGREDKQKIARSINLIIEEIDSIL
                     NFGNCNEYNNVSNYNLRWELNLQIDEIVGKLKKDGIDTEISYRAYSEKIKLSCEKIIK
                     NLVSIIIIIYRNIDDDSIDKEADIYKFGKAKTRDLEDIKIIFEIFLEYDEKDDYARIV
                     EIDKNYNVFEFRVVPLKIADLFEENILSQLEKGIFLSATLSLSESMSYFKNTLGIDRV
                     KNVEKIIEPIFDYKNRVSVVGFSDICEYRNSEFPNEMSKIISNISKITEGHTLALFNS
                     KDRQEKTYEILKKYLHSFNLEIYADKKGIRHLNDLNRKCVVLGSKGCFEGVDIPGDGL
                     VCVTLDKLPNLNPKDPLYFTIMKKYGIDYYTINYPQMTIKVKQAMGRILRSKYDYGCF
                     VIFDVGTNISVLKRLEKDLHDCKISKVNSNEFYTYIRRHLNKSRSLILKSVIFDTIKA
                     LNVDAKMDNNDVDKDIIKKDINENIRQRAVKGEVYHIDIIKKDMKVKYFDRNYLINLD
                     IFMREEDKN"
     gene            155463..156062
                     /locus_tag="KRH23_000142"
     CDS             155463..156062
                     /locus_tag="KRH23_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="viroplasmin family protein"
                     /protein_id="HHS5223442.1"
                     /translation="MAKQKFYAVKKGKNIGVYNTWDECKKQVNGFSGAEYKSFSTFQE
                     AKEYIDGSEKLSFQEDKEFIEAYVDGSYEHSVKMYGSGVVILKNNEVIKTYSEKGKEK
                     TLVSMRNVAGEIEASKIAMQYCIDNNVQNLILYFDYEGIEKWCTGVWKTNKEGTIAYK
                     NFYDSIKNKLNVKFTKVKAHSGNKYNEEADKLAKKAIGV"
     gene            complement(156304..158433)
                     /locus_tag="KRH23_000143"
     CDS             complement(156304..158433)
                     /locus_tag="KRH23_000143"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008379 - thioredoxin peroxidase activity
                     [Evidence IEA];
                     GO_function: GO:0051920 - peroxiredoxin activity [Evidence
                     IEA];
                     GO_process: GO:0098869 - cellular oxidant detoxification
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HHS5223443.1"
                     /translation="MPNLPSLGSKAPDFKANTTNGPIRLSDYKGNWIVLFSHPGDFTP
                     VCTTEFLCFAKYYDEFKKRNTELIGLSVDSNSSHLAWMYNISLLTGVEIPFPIIEDRD
                     MRIAKLYGMISKPMSDTSTVRSVFIIDNNQILRTILYYPLTTGRNIPEILRIVDALQT
                     SDRDNIVTPANWFPGMPVILPYPKNYKELKNRVNSCNKKYSCMDWYLCFVPDNYNDEE
                     VSKKIDNTCSWKKEHTKNIENECNCEHEHHDYLNKALDCKQEHKTDIKDDCNHEKKHT
                     KNTNKVHNSKQDKFKDKSCDEMNFNYDKDESCDKINSSYNKEDSSYEDFYKHNYKNYD
                     YTSEKNTKKIAMKTLKDSKKLVRPQITDPYNPIVENANCPDINPIVAEYVLGNPTNVD
                     AQLLDAVIFAFAEIDQSGNLFIPYPRFLNQLLALKGEKPSLKVIVAIGGWGAEGFSDA
                     ALTPTSRYNFARQVNQMINEYALDGIDIDWEYPGSSASGITSRPQDRENFTLLLTAIR
                     DVIGDDKWLSVAGTGDRGYINSSAEIDKIAPIIDYFNLMSYDFTAGETGPNGRKHQAN
                     LFDSDLSLPGYSVDAMVRNLENAGMPSEKILLGIPFYGRLGATITRTYDELRRDYINK
                     NGYEYRFDNTAQVPYLVKDGDFAMSYDDALSIFLKTQYVLRNCLGGVFSWTSTYDQAN
                     ILARTMSIGINDPEVLKEELEGIYGQF"
     gene            158699..158947
                     /locus_tag="KRH23_000144"
     CDS             158699..158947
                     /locus_tag="KRH23_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5223444.1"
                     /translation="MMICFAMTFALVLINSVMGVHIGLDYYFLMGSVLTVCLTIGIVL
                     CNARKIFDSKAIHKTRTKTVSNNKKQKSHSRDIKRKIS"
     gene            159113..160504
                     /locus_tag="KRH23_000145"
     CDS             159113..160504
                     /locus_tag="KRH23_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HHS5223445.1"
                     /translation="MNFRDLFEKAIDFIDEKRKSIVAISLSTLGVIALIIVFFLSSNE
                     FSVGNEANELLKIIEKRQYSIAVDYYTSIEKKFSDSKMERFNKSVSKKINKLLLNSGD
                     KYLDGDISQESFIGLINTVKELNKISIDVDDLLVQADRVREMYKEENTTYDIAINYIS
                     TVSILNGMGSNLDVYKQNIETIKESRDVYDSAVKDQKAYKYYEAIEKYNKVLKEDEKY
                     YSMAQNGKEQCIEEMYDYYISRAEEANTSGDYERALQYIEYLKEDYSDDEKVQSLEKK
                     YKKNLSLYTLTSDDIINVIAKKSGKDKANLSINSLPQMIKNNKYYYAEVYEYDKLINE
                     VLVSAKTKDLYSYKDGKKDYKVDYGDGYFRILEDGSYQFGITKDKAKFVLTNTLDEKE
                     NKYKKIDILDIEKADRYVKSKKSLEELFGKYKNIYYYAVVNKGLFRGKEVYAINIYNE
                     KIYAISENGLNEY"
     gene            160619..162088
                     /locus_tag="KRH23_000146"
     CDS             160619..162088
                     /locus_tag="KRH23_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanW family protein"
                     /protein_id="HHS5223446.1"
                     /translation="MSNVNKKLVIAIGAVALVVIIFIGIMCMQFKGEKIAKNTYVNGV
                     NIGKLTKSQAKQELAKKYKLENVDFNYNDKSWKVKSKDLNLSTDLDKTVENAYNLNRK
                     SAFFGNLSKTISANFGKKSNLVVVINYDKNKLKAEMEKIAKEIDVDVKDATLDISGEK
                     VKVIPDSDGLKMDISKSMENFDNQTKKGNYKNELVVKATPAKVKKEQLANIDTNLGTY
                     STTFKTSQINRSINIKLATDNISNVLLMPGETFSFNKHTGKRSKENGYKSAPVIMEGE
                     MEEDYGGGVCQVSSTLYNSVLYAGLEIVNVKNHTIPSSYVPKGRDATVADSGIDFLFK
                     NNLKHPVYIKNYVSGNQIVCNIYGSAEDKQNITISTKLDGVSQTTMKRVNDPTMPKGK
                     EKVDKSGRNAYSVSTYRTFNDANGKKIKTEKIANSYYPKKEGIILVGTMEPKPEEKPN
                     TDENKNNQNTNNQNPNNQQKPETPPTDNKPNETQPQPQA"
     gene            162153..162746
                     /locus_tag="KRH23_000147"
     CDS             162153..162746
                     /locus_tag="KRH23_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHS5223447.1"
                     /translation="MNLNNITNYVQSICENISNVLDVDVTLVTKDLTRIAGTGIFRGK
                     IGETISEKSVYSLVLKDGKSYVINKEIEENCNKCANRENCKELADICTPVKMGEHILG
                     ILGIAAFNEEQKEKILSKDKELTAFVRSMSDLISFKLDELYKQEVKTIDDLEREAIEN
                     AIKKYGSNTEGMKKVAEALNIGIATLYRKVKKFNIKS"
     gene            162877..164274
                     /locus_tag="KRH23_000148"
     CDS             162877..164274
                     /locus_tag="KRH23_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HHS5223448.1"
                     /translation="MEVSIILVKDIKQDIESMPRKILDISLIEDNKSDLTFFNIEEED
                     GDETLKALKQSYVTTNYKEETLLNLQGALNSKSDTTSKELKLESYKRYNNALDLAYKN
                     YITSAINMVNKALEINPKDIDILNLRGLLKLLKCDFAKSFESFYTALCYENNHISRKY
                     VNLISSEDFKTFLGRYNHSIRFINEELNYESIHILENIIEEEPELIEPYVILSLLYDK
                     LGNVKKREGYLDKLKELDKDNPVFEKNEEEKEDTSKKEEIKKVKRKKSILPYIIVGCV
                     LIGMGIYLIQSKKRIENLNNQISSKEEKLSETDKKLGETSKKLEKTNKELNEVKNKEP
                     EREITVADEEDLYYQALNLKKNKEYEKAIDNFKSVVSSGKTKKYISESIYQLAITNKL
                     LGNKDEAIKYYKKYINTYTKNDQYYDDSYYELGMLYYDNGDLKNAQQTFYSLRSEVPD
                     SMYNNSKIKEILSEK"
     gene            164456..164827
                     /locus_tag="KRH23_000149"
     CDS             164456..164827
                     /locus_tag="KRH23_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HHS5223449.1"
                     /translation="MKVFNQLVIILSIWVIGEYISSFIQGIILIPGSIVGMLLLFLLL
                     QFKVLDLSSIENVSGFFLDNMAIFFIPAGVSLIKSLDLIRENVLVLLLVICLSTLIVM
                     YTTGIIVEKMIKKKEEGQKNV"
     gene            164820..165509
                     /locus_tag="KRH23_000150"
     CDS             164820..165509
                     /locus_tag="KRH23_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HHS5223450.1"
                     /translation="MYNVLQTPVFGIIVTIVFFNLGRYIQRKTSNPICNPLLIAIVGI
                     ILFLSISKIPYENYKIGADSLNFFLGPVTVVLAVPLYKQFELFKKHMFEIIVGIGCGI
                     VISFVSVLIIGKIANSDVSIINSLIPKSITTPMGISLANSLNGIESITVVAIIFTGIF
                     GGMVASTVFKLGNINHPVAKGIALGTSAHALGTTKAFELGEIEGAMSGVSIGVSGTIT
                     VILIPIIMNFI"
     gene            166029..166895
                     /locus_tag="KRH23_000151"
     CDS             166029..166895
                     /locus_tag="KRH23_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HHS5223451.1"
                     /translation="MSEVKNTLQKHPVLRYSTMLFGMLMTSIGINGFLRPAHLLSGGA
                     TGIATSINYLTNINVGLLTFLINIPIFILGFIYLEKEFCISSLVNMIVFSLLLGATQE
                     ISNIIPIHDILLQSVYGGILSGLGVGVVFRTRSSQGGTDIIAAILKIKKNIEMKDTAL
                     AINGLIVLTGSFLFGLDLALYTLIGLFLNAYSMSFIKDAMNYQKSVMVMSNEVDLIAE
                     DIMKSLVRGVTFLDAEGAYTHQKKKIIYTIVSSNEIPKIKDIALKYDKKAFISVNDVT
                     EVKGRGFKAKDL"
     gene            167137..167946
                     /locus_tag="KRH23_000152"
     CDS             167137..167946
                     /locus_tag="KRH23_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MORN repeat-containing protein"
                     /protein_id="HHS5223452.1"
                     /translation="MNLSKEYVNLYDNYLKYINEVNKEIRSIKNMKKRVLKRGDFAPE
                     NEVLELEGKTIRDIDDVDTKKPKNKIYKFSNGDVYVGKFLEGKMEGKGSYTFFVDEGT
                     VMEYIGEFKEDKKNGKGNFIFSNGNEYIGYFEEDMMSGIGNMLYSSKDEYIGTWKNGK
                     KDGKGIYKWSDGCIYAGEFKGGKMEGYGICYNSKGEVLYEGEWKNNLIHGKGTYIWEK
                     GKKYIGEFMHGKKHGQGTFYLNNELVYEGTWKFDKPSIFDRTLDEIFSLRL"
     gene            168090..169154
                     /locus_tag="KRH23_000153"
     CDS             168090..169154
                     /locus_tag="KRH23_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CAP domain-containing protein"
                     /protein_id="HHS5223453.1"
                     /translation="MKRLIALVLVVLIVLFYSPELLKEGYDLKEKFFQSEIWNELLDK
                     ININDNSKKDKKEKSQNLQSNNTEGENLGESDIKNFEKISLGDNLSYVLSSIGKPGRI
                     DISEYGFDWYVYNQYGKEFAMVGLENDEVVALYSNSINSCENQDIKLNQDRQTVRTKI
                     TPLKYKRKGNTRYIINSENQYDIISKEGKYITIFYDIHEENRVCSYLIIDKSTEDEFE
                     NLYPDDSEELKKCFELEVIDIVNSVRNQRGLNSLRYSEQATLSSRKHSEDMRDNNFFD
                     HVNKKNETPFDRMKREGIVYTSAGENIAAGQINAIYAHEAWMNSEGHRKNILGNYNNI
                     GVGVIFGGSYKTYYTQNFYK"
     gene            169182..169901
                     /locus_tag="KRH23_000154"
     CDS             169182..169901
                     /locus_tag="KRH23_000154"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HHS5223454.1"
                     /translation="MTSWKKKTVYKCLIAVVLFCGIVLISNFSKVSALMMDTNGNVLI
                     KHGSREKKLIAITFDDGPHPKETSQVLDVLKKYNVKATFFIAGKHAKWYKEPLVRASK
                     EGHEIGNHTFNHPDISNLSSSQIEEEIVKCEDILKEVTGKKPTLFRPPFGSYREKELI
                     EIAKKHDYKVVLWTGVDVKDWKNPGANSIADKIINKVQNGDIILLHDYATNDTVEALD
                     MFIPKMIEKGFKFVTVSELIK"
     gene            169925..170509
                     /locus_tag="KRH23_000155"
     CDS             169925..170509
                     /locus_tag="KRH23_000155"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004049 - anthranilate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0000162 - L-tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component II"
                     /protein_id="HHS5223455.1"
                     /translation="MILMIDNYDSFVYNLVQYIEELGETVVVKRNNEIKISDIEELNP
                     EVIVLSPGPCSPKEAGICIDIVEHFKGKKPILGICLGHQTIGHVFGGDIIKAQQPVHG
                     KVYSINHTNKGVFRGLKNPLNVTRYHSLIVDSNTVPKELEITAITDKGEIMGIRHKKY
                     LIEGVQFHPEAILSEYGHEMLKNFITEARERVHM"
     gene            170511..171860
                     /gene="pabB"
                     /locus_tag="KRH23_000156"
     CDS             170511..171860
                     /gene="pabB"
                     /locus_tag="KRH23_000156"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046820 - 4-amino-4-deoxychorismate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0008153 - 4-aminobenzoate biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0009396 - folic acid-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HHS5223456.1"
                     /translation="MIREINTKLNSFEIFTIFRNEHDSFILDSAMDKEKLGRYSFISS
                     QPFKVLKYKDTDENPLEVLKEELHKYRVVNDTNLPFVGGAVGYLSYDLGNYIENLPRT
                     AVDDIEMPDMYFGFYNHVIVIDHLVQKTYIATPNIDIELEEKIIDDIEQRILKEEKKG
                     IDSICYEEKEVTPIRLKSNFTKEEFKNAVQSVREYIRQGDIYQANLTQRFSGETELTS
                     FELYRDLRRFSPAPFGAFLNFEDAHILSNSPERFIRCVNKRIETRPIKGTRPRGKDKE
                     EDLRLQQELRNSEKDRAELLMIVDLERNDIGRISKTGSVKVPELFVIEPYANVNHLVS
                     TVVGELKDDKDATDVIKATFPGGSITGAPKIRAMEIIDELEPTQRNVYTGSIGYIGFN
                     GDMDFNIAIRTIIKNDKKVYFQVGGGMTWDSDPDEEYQETLDKAKSIMKALRGYYEE"
     gene            171850..172593
                     /locus_tag="KRH23_000157"
     CDS             171850..172593
                     /locus_tag="KRH23_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class IV"
                     /protein_id="HHS5223457.1"
                     /translation="MKNNVGFDSSLSKFGIGLFETIRVKNGIAVDLDIHIERMLSSIN
                     CLDLDINYKKDFLINEIVTYIKKENVINKALRITVFDEGYNISIRDIPYNQETYEKGF
                     KLAISPIVRGNSLIHRHKTTNYFENIYTKNIANKTGYNDGIFLNSEGVILECSMSNIF
                     FIKGERVYTPSDRLPILNGIIKKRIIEICDELHIELIENEINISEISSFDFVFVTNSL
                     MGAIKVTEIDKIKFNKENVVFDKIVKLLE"
     gene            172627..173328
                     /locus_tag="KRH23_000158"
     CDS             172627..173328
                     /locus_tag="KRH23_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5223458.1"
                     /translation="MIGCIYEVYNEEMTKIIENQNTLAVYLVGSSKDVDFTLYDVEIN
                     DIDVFVFVKEGEKQERILFKKKGIEFDVNYFSKDGVKKLLSNREYFFVKEMKDAKVLF
                     DRENISHIIKDISRNIYLEGPSKMSLEEKSFIKQDIGAKISNLKNKEKFDVFEYHFLT
                     NLYLKDIIIGYFNINDKWVPKDKKLLKVLKKENNELFELVSKVSENYDYQRLLDVYNY
                     IFKEIETKEVIKLIF"
     gene            173354..173926
                     /gene="folE"
                     /locus_tag="KRH23_000159"
     CDS             173354..173926
                     /gene="folE"
                     /locus_tag="KRH23_000159"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007287029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003934 - GTP cyclohydrolase I activity
                     [Evidence IEA];
                     GO_process: GO:0046654 - tetrahydrofolate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HHS5223459.1"
                     /translation="MNKVDKEKIQHAVREILEAIGEDPDREGLIETPNRVARMYEEIF
                     SGLSEEPRDHLKVLFADEKHEELVLVKDIPFYSCCEHHLVPFFGKAHIAYLPKGGRLT
                     GLSKLARVIDTLAKRPQLQERITKNAADIIMEELQPYGVLVVVEAEHMCMTMRGVKKP
                     GSKTVTSAVRGIFEKDIASRAEAMSLITMK"
     gene            173990..174781
                     /gene="folP"
                     /locus_tag="KRH23_000160"
     CDS             173990..174781
                     /gene="folP"
                     /locus_tag="KRH23_000160"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004156 - dihydropteroate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009396 - folic acid-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HHS5223460.1"
                     /translation="MFDYGKRTYIMGILNVTPDSFSDGGDFNNLDIAIQHAKDMVDQG
                     ADIIDLGGESTRPGHSYVDSDEELRRVIPVIKKLKQELDVPISVDTYKADVAEEALKL
                     GVTMVNDVWGLRKDKNMASVIGKYDAEVCIMHNQDGTNYDKDIMESIKDFFKVSIEMA
                     MSCGVKKEKIVLDPGVGFGKDFEQNIEVLRRLNELKDLGYPILLGTSRKSVIGKVLPV
                     EPKKRLEGTIATTVLGIRDGVDIVRVHDVYENLMAARMTDAIYRK"
     gene            174792..175157
                     /gene="folB"
                     /locus_tag="KRH23_000161"
     CDS             174792..175157
                     /gene="folB"
                     /locus_tag="KRH23_000161"
                     /EC_number="4.1.2.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004150 - dihydroneopterin aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0006760 - folic acid-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroneopterin aldolase"
                     /protein_id="HHS5223461.1"
                     /translation="MDKILLSNLGFYGYHGVLKEENFLGQKFFVDMELYIDSREAGLS
                     DDINKSVSYAEVYNVVKDITENKQFNLLEALAENIAEEVLNKFILINGVMVRVRKPEA
                     PVNGIYDYFGVEIRRARDE"
     gene            175150..175656
                     /gene="folK"
                     /locus_tag="KRH23_000162"
     CDS             175150..175656
                     /gene="folK"
                     /locus_tag="KRH23_000162"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003848 -
                     2-amino-4-hydroxy-6-hydroxymethyldihydropteridine
                     diphosphokinase activity [Evidence IEA];
                     GO_process: GO:0009396 - folic acid-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HHS5223462.1"
                     /translation="MNKAYLGIGTNMGDRFDNLSRACELLKNSDSIYKVKESSLYETK
                     PWGYTEQADFLNMCVEIETEFEPYELLEYCQEIERELHRERIVHWGPRTIDVDILFFN
                     DVVSTDERLTIPHPRIQDRAFVLIPLMDLNEELIINEKTIKEHLNLLSAEEREEVKEL
                     VGYERKPI"
     gene            175637..176422
                     /gene="aroF"
                     /locus_tag="KRH23_000163"
     CDS             175637..176422
                     /gene="aroF"
                     /locus_tag="KRH23_000163"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003849 - 3-deoxy-7-phosphoheptulonate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HHS5223463.1"
                     /translation="MKENLFNNNSKIEINTNNKKITVKKDKLIIAGPCAIESYEQLLE
                     TAKFVKSQGANILRGGAYKPRTSPNSFQGLKKEGLEILKAVKDEVGMAVITELMDVRD
                     MDELYSISDIIQIGSRNMQNFTLLSEVGKQNKPVMLKRGIASTITEWIGASEYIAIEG
                     NSNIIMCERGIRTYNDYTRNTLDLAAVPIIQKETGLPVVVDPSHATGVRYLVKPMSLA
                     SFACGADGIMVEVHPDPENALSDGAQSLCFNEFEDLMKSINNY"
     gene            176641..178467
                     /gene="dnaG"
                     /locus_tag="KRH23_000164"
     CDS             176641..178467
                     /gene="dnaG"
                     /locus_tag="KRH23_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed RNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006269 - DNA replication, synthesis of
                     primer [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HHS5223464.1"
                     /translation="MLTQKITPEGDNMNDIKDIIEEIKARCDIASIISEYMNIKQSGA
                     NYKGLCPFHGEKTPSFYINTSKQIYKCFGCGEGGDVINFVMKMENLDFMDAVKILANK
                     CGIEINTNMNEETRIKIEKSKKFQDIHTEAARFYLSNLLGSKNLGYEYLRIRGLDDKI
                     IKKFGLGFSLDSWNSLMNTLISKGYKKQDLLECGLIAKNRDGTNCYDKFRNRVMFPIF
                     DYRGNIIGFGGRVLDDSLPKYLNSPDTLIFNKKQNLYGLNFARKNLESKTIVLVEGYM
                     DLISLYQYGIKNVVATLGTALTEQQGILIKRYADTAIISYDSDEAGIKATLRAIDILT
                     KLGINVKVLDLKDAKDPDEFVRKYGLSDYKKAMDVSTHYIKYKIDHLKKEFNIQKDEE
                     RVKFAKEASKIIKQLTSPVEIDFYTKYLSNQIDINVESIKREVYGKNYNKPYNNKNQK
                     KIEEKVIEKVEVRQDGKQLVEETLIKIMLEDKKIREIALLKVEESDFLLKESKEILNY
                     MIKNQELDKITIDKLKSLNISEEYLKELNSISLNSINLENTKEIEGIITNIRKNSLEE
                     QINSLLREQQELENNNDMKEVDGRVMEIALKIVEINKILKSL"
     gene            178485..179651
                     /gene="rpoD"
                     /locus_tag="KRH23_000165"
     CDS             178485..179651
                     /gene="rpoD"
                     /locus_tag="KRH23_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HHS5223465.1"
                     /translation="MENKSNKKELKKVTAKTLIEKGKKQGSLTLAEIMEAFSETELDK
                     DQVENLYETLGNLGIEITETKNYKADIDFSVADDDLSIGHLDEDAEAISHDDSSAIEI
                     ETVDLSLPKGISIDDPVRMYLKEIGKIPLLKPHEEVEFARRMHEGDEIAKQRLVEANL
                     RLVVSIAKRYVGRGMLFLDLIQEGNLGLIKAVEKFDYTKGYKFSTYATWWIRQAITRA
                     IADQARTIRIPVHMVETINKLIRVSRQLLQELGRDPKPEEIAKEMEMTEDKVREIMKI
                     AQDPVSLETPIGEEEDSHLGDFIPDDDAPAPAEAAAYSLLKEQIEDVLGSLNDREQKV
                     LKLRFGLEDGRARTLEEVGKEFDVTRERIRQIEAKALRKLRHPSRSKKLRDYLD"
     gene            179816..180505
                     /locus_tag="KRH23_000166"
     CDS             179816..180505
                     /locus_tag="KRH23_000166"
                     /EC_number="2.1.1.217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:0160105 - tRNA
                     (adenine(22)-N1)-methyltransferase activity [Evidence
                     IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine(22)-N(1))-methyltransferase"
                     /protein_id="HHS5223466.1"
                     /translation="MKLTDRLLKIASLVSDGKKIADIGTDHGYIPVYLLKEGKVPFAV
                     LADVNKGPLDNAHKEVIQNNLLDKVDLRLGSGIEILEIGEVEEVIIAGMGGILISELL
                     EAKKEVAHNVEKLILQPMQAQEELRYYLLNNGYEILEEVLVREDFRIYEIIVAKYTGK
                     NTIIEDEIYYEVGIKLLENKDSLFNDFIEKKIKTYSSIVNKLEGKNGEAIDKKRKESE
                     VAIKKLENLIK"
     gene            180519..181616
                     /locus_tag="KRH23_000167"
     CDS             180519..181616
                     /locus_tag="KRH23_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0051540 - metal cluster binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HHS5223467.1"
                     /translation="MLLKSLTRKIEKKYPLNLAEDWDNVGLIVGDFDMDVKKVLVSLE
                     ANEDVIDEAISKNIDLIVTHHPFIFGKINKINSGDLKGRLIQKLIKNDISLYSMHTNF
                     DIAFDGLNDYFMEIMEFGNSKVLDITKSENLYKLAVYVPHNYSDELRKVLSNSGAGHI
                     GNYSDCTFSIEGEGQFKPLEGSNPFLGSVNDIETVNEVKIETVVPQKLLGGVISSMLD
                     AHPYEEVAYDLYKLENKGEIFGLGRISKLDKSMTLESLSRKIKEKLNMKHIRVVGNLS
                     TDITKVAVVTGAGSEFVKKAKRQGAEVLITGDVKYHEAQDALDIGMCIVDCGHFDTED
                     IFKNVMKRFLDEFSEIEVIKSNVYLNPFSTI"
     gene            181679..182251
                     /locus_tag="KRH23_000168"
     CDS             181679..182251
                     /locus_tag="KRH23_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HHS5223468.1"
                     /translation="MKVAVIFHSVCGSTYLLAREYKEALEEMNIEVDIFRVSDEVAKT
                     LPQYYLINSKEYKDEFESINVIKSGKEILDYDAIFMGSPTYYGNVSGPMKMFMDSFSD
                     IWVGAPLSGKIFGCFATAGSQHGGGELALQAMNIFAQHMGMTLLSVPCSVRGGYPAYG
                     ILHIAGDNSDIRPNDDAKIGIRDYLKRLNI"
     gene            complement(182311..182778)
                     /locus_tag="KRH23_000169"
     CDS             complement(182311..182778)
                     /locus_tag="KRH23_000169"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HHS5223469.1"
                     /translation="MFKEMRLKKREMTKEDTVEVLKNGEFGTFSTISENGYPYGVAVN
                     YVYFNDSIYFHCARNGHKLDNISKNNKVSFLVVANESVIPDKFSTTYSSAIVFGKACT
                     VENEEKKNALVEIIKKYSKGFFEEGMKYIEKDMNLTTVVKIEIDHISGKASRL"
     gene            complement(183164..183640)
                     /locus_tag="KRH23_000170"
     CDS             complement(183164..183640)
                     /locus_tag="KRH23_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HHS5223470.1"
                     /translation="MLSKAEIKYFNECASEILSSEKVQLMRTFPHHGNVSCLEHSLSV
                     AYYSYLLCKKLHLSVDIQSVIRGALLHDFFLYDWHYKGNRKGLHGFTHPREALKNATL
                     FFQINEKETDIILKHMWPLTVKPPRYKEAFIVCLLDKFCCLVETLKIHSLLSPYHV"
     gene            complement(183760..184851)
                     /locus_tag="KRH23_000171"
     CDS             complement(183760..184851)
                     /locus_tag="KRH23_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5808 domain-containing protein"
                     /protein_id="HHS5223471.1"
                     /translation="MSKIECLFTIFPVLILMYATFYFMPYFVGKKHIYGVSIDQEHKN
                     YNYFIKLDKEFKKLLSLGFIIDFILVFILVFTFNKLELSYFIGIIGFLLYESILYIHT
                     HKKAKKLKSEIYSKLGHIDIDSKLIVDMDFINKKNKIIKKFKIIYLIPILFTLGMSIF
                     IAFNYNQLPDSIATHWNINGSPDVFIDKSFLNVFKLIGTDFCLMVLLYITSIGSIKSR
                     IKIDTNRIEESRVENIKYLNKIGYLFLILMIIMTTQFFTTLLSIKTKLSTAMNITTLL
                     VIIYLIATYINSPNLKFNSSYSPEEDEKYWIAGIMYNNPNDPSLMVNKRFGIGWTINF
                     GNPLGKILYIAIALLLIFSLFSLIKSLLL"
     gene            complement(184844..185233)
                     /locus_tag="KRH23_000172"
     CDS             complement(184844..185233)
                     /locus_tag="KRH23_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HHS5223472.1"
                     /translation="MVLNLDFNSDKSIYVQIKEEITKAIASGELKINESLPSVRSMAE
                     NIGVNLHTVNKSYNELKEEGFLNIDRRKGAIVAQLPMKIDNTTRQKNKLDLELLVAKS
                     YLSGISKEEFLSLSSSLFDKYEVKYYE"
     gene            185425..185871
                     /locus_tag="KRH23_000173"
     CDS             185425..185871
                     /locus_tag="KRH23_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5223473.1"
                     /translation="MLTYLMKRQMHKKDDGMSKPMMITGAVITGVGAYAVYKMVKSHK
                     SNSQMVNTNYYGNSDYDDYKYDEFDYDCDCRDTKQDYEYEELKKKVKEFNSRRINCEN
                     CPHVSQEEMMQYVNSVKDVKEEIDLHEDAKKDNIYKEDEYKKYEEE"
     gene            186131..186856
                     /locus_tag="KRH23_000174"
     CDS             186131..186856
                     /locus_tag="KRH23_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HHS5223474.1"
                     /translation="MKRKEIVMLKLLIVEDDSTISFGIKYALEQEGFSIDISKDLSSG
                     KEMISSNEYSMILLDVTLPDGTGYELCQYIRGFSQVPIIFLTACDEEVNIVMGLDIGG
                     DDYITKPFRIRELISRIKAVLRRKGNTSEENKKILKFGDLSIYTLEARVYKNDKEIFL
                     TSVEYKLLLILIQNKNTVLSRTQILEKLWDVTYDFVNDNTLTVYIKRLREKIGDDLCE
                     PIYIETVRGIGYKWIGSENSVSI"
     gene            186834..188087
                     /locus_tag="KRH23_000175"
     CDS             186834..188087
                     /locus_tag="KRH23_000175"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HHS5223475.1"
                     /translation="MKIVFLYNPEVKKFLSKYVTLMFIVIIISIGFSIINVSLTKEMV
                     VRNNQAIIGTLSSKYPNLESDIVDIITQGKSMENIDYGQKILIKYNYDKSIRINSEPI
                     ISKLVLETIKINIILVCIIFILIFVLVVRYFKSIYNDLSDMTKYVYYSSEGKQFDMKN
                     KNQEGQIGLLKTELLKMTTILNEKVELLKREKIFLNNTISDISHQLKTPMTSLIMLND
                     LLYNDVPYEVKIDFLNKIKNQLNRMDWLIKSMLKLSKVEAKVINFKKDKVKFSELIHR
                     AMLSMKIPMEIKNQKLTIEGNDNVSYIGDIDWSVEALVNIIKNCVEHTPEFGNIIITY
                     KENPLFSELIIKDEGEGIDKKDIPHVFKRFYRGRSSSKEDSVGIGLAMSKSIIESQNG
                     DIYVNSEKGKGTEFHIIFHKMYDSD"
     gene            188167..188844
                     /locus_tag="KRH23_000176"
     CDS             188167..188844
                     /locus_tag="KRH23_000176"
                     /EC_number="7.6.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHS5223476.1"
                     /translation="MEILRVENLTKSYGKNETKVDAIKNVSLSVEKGTFIAITGPSGS
                     GKSTLLHLLGGVDRPTSGKVYINDVDIYNLKTKDLAIFRRRNIGLIYQFYNLIPVLNV
                     KENILLPAELDNRDIDREYFEDLMKTLGLIDREKHLPNQLSGGQQQRTSIGRALINRP
                     SIILADEPTGNLDSKNSKEILELLKLSVKKYNQTLIMITHDKNMALQADRIISIEDGI
                     IKSDEVM"
     gene            188845..191406
                     /locus_tag="KRH23_000177"
     CDS             188845..191406
                     /locus_tag="KRH23_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHS5223477.1"
                     /translation="MNLYTSLTIRYLKQNKRRTIVTIIGIILSTALICGIGNIFESFM
                     DYQMRETIKNDGSFHVTFYDVNRKNAEYVTKSAEIEKHAFTKQLGYSKLENSENAILS
                     IKQYDKNAINGYKVSIKEGRFPAKEGEIVLSESIINLIDDKFKIGDKITLKVGDMFDS
                     SKKKIDSMTFHEGDYIANEKDRTFKVVGIIEKPGFERYNGIATAIAYFNPMNNYNDTI
                     NVSVAVRNPKDVYKISNKISKNIYSNKDKEAVSDMIKYNEHLLRLQGASKYSNINSSI
                     KSIIIAVTILVIICTIATVYNSFSISINERKKQFGILNSIGATSSQIKRLVFIEGIII
                     SLIGIPIGLISGTVAIDLLFKIINKYFTESVVTKMSLQIVYNPIIIIVSIIIVLLTIF
                     ISILLPAISASNISPLNVIKNTGEYKVGKIKSSRLIKMIFKTEGVLAYKNIRRNRKKF
                     IITLFSLMVSIIIFISFSGFTLLLLRGEEIRNSQRKYDLYLTAKNTARSVEDTISELE
                     DIDGIKNFELATGQYVSIRVSENKINKSKEDLIRKYYQKYKIGDSYEYDFSNNELIFP
                     GDFAVKNKINNLVQGSFNKERAIEENGVILVRKSAFEENGKKGVVELTNYKVGDTVNC
                     EYLDENALSKKVKVKILAITDEERLGLGYQNMGLQFITYDEVAKNLNLKLSKSLIFID
                     SGGSIKTKKEIEALANKNNFNFYDESASNESEKQDLKVIKIFVYGFIVVISLVSVTNI
                     LNTVSTSINLRKRELAVIQSIGVTPKGFRKMIYLESFIYGILSLLFGIPISIGIILIM
                     NKLISGVIEFSPIIPWTAIVICIVSVFIITFIAGYIPMSKLNKENIIDNIRRESI"
     gene            191627..192901
                     /locus_tag="KRH23_000178"
     CDS             191627..192901
                     /locus_tag="KRH23_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster-binding protein"
                     /protein_id="HHS5223478.1"
                     /translation="MITISHITAKNMYKSLEERINKFPQGAPPSDTLYKILNVLYTEQ
                     EAKLVAQLPIKPFRVKTAAKIWSVSESEAYRVLDKLASKALILDIEDNKGKKYIMPPP
                     MAGFFEFAMMRTRHDIDQKLLAELYYQYMNVEEDFIKDLFYSTETKLGRVYVQEEVLT
                     NDNEVSILDYERATHIIDESTHIGISMCYCRHRMQHVGKACDAPMDICMTFDNVANSL
                     INNKFARRVDKIECKELLHQAYEHNLVQCGENVRKGVTFICNCCGCCCEAMVAAKRFG
                     NLHPVQTTSFIPNINHENCVKCGKCITACPIDAISKVKEDGKEYIKIDEDRCLGCGVC
                     VRNCHKNSIMLLKRDEKIITPANSVHRAVLMAIEKGQLQNLIFDNNALASHRAMGAIL
                     SAILKLEPAKKILASKQLKSVYLDKLLSMNDK"
     gene            complement(193062..196103)
                     /locus_tag="KRH23_000179"
     CDS             complement(193062..196103)
                     /locus_tag="KRH23_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp20"
                     /protein_id="HHS5223479.1"
                     /translation="MFKQRLSKLLSSTLVLSMLFTAAPNITFADNTKDNSEKYQSSDI
                     ELHDYSKNAESYTKTKALAKEKIQTLLSKYGAVSAQYALIDNGKIEISGNGGVYSKQD
                     NKNLNKDNMYSIASISKMFTTTAVMKLVDDGKLNLDTPVVKYIPEFKMADDRYKEITP
                     RMLLNHSSGLMGSSFKNTILLADNDSYGHDNFLKELQKQRLKAKPGAFSVYCNDGFTL
                     AEILVERVSGMSFTNFLDKYINNPLNLQNTKTPENSFDSSKLAKAYVPYWEDAVPQDN
                     LNAIGAGGLYSSAENLCTFAQTFMKNSNGILSPASVKAMENKEYLNGLWPEGEDSILG
                     YGLGWDCVNTYPFNQYNLKALTKGGDSLLFHSNLIVLPDENMAVAVLSSGGSSQLNEI
                     IGQEILLSALKEKGKIKEIKPDKTFSKPQQVKMPSSLKENSGLYASSNMIKVDVNDNG
                     TLTVSSPYIENGPEDKYVYIGQDRFVSEKGNSCLKFVKEKNNITYLNMSSYDDVPGLG
                     QTASLYYVAQKIDDNNISNSVKEAWKKRNGKDYYLVDEKYTSQSYMFGSVKATLALSD
                     ETPGYIVNTKIMDENNSNAFIEIPGVIGRDLSDIKLHKENGTEYLSFGTLTYVSEDSI
                     TNLPAEKSFTCELESNGYAKWYKIGDDIANKKIEVNLPQNSSFAVYDDKGVPVNYSLV
                     TKNNRVRLPKGGVIVFLGSPNARFEVTYQDEVNASALTGTDRYETSIKISQAGWENAE
                     NAVLINDSAIADALAATPFAYKKNAPILLTGSSQINEKTLAELKRLKVKNVYVVGGEA
                     SINEKSLDTIKSNNISVSRISGSDRYQTSMNIAKELNNISNISKISVVNGEKGLADAV
                     SIGAVSAQNDMPIILTNENSNITEINNLFKNKKIDKSYVIGGEYTVSKNIESKLQNPQ
                     RISGSTRNETNAKVIKEFYKDSKIDNLYVAKNGMNKQDDLIDGLSVGVLAGKTKSPVM
                     LVGNSLDYNQKELFKTMRFKSVTQIGGNGNENSFKQIKEIA"
     gene            196310..196609
                     /locus_tag="KRH23_000180"
     CDS             196310..196609
                     /locus_tag="KRH23_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HHS5223480.1"
                     /translation="MYKNINKKQLKEMMKNEKDILLLDVRTKDEFKEYKIENAINISL
                     QELINNIDEIYDYKDKKVVVYCRSGHRSVTACNLLAEEGFEHLYNLNSGIIDYMS"
     gene            complement(196847..199075)
                     /locus_tag="KRH23_000181"
     CDS             complement(196847..199075)
                     /locus_tag="KRH23_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
                     /protein_id="HHS5223481.1"
                     /translation="MRHLKKTNSLKEILNWNNIKNLRPSKGLKNILEIFKSDLKDIRG
                     NYAVLVIVLGLAFLPSLYAWFNIKASWDPYGSTANMLVAVTNEDKGNEIAGQKINVGD
                     QLIEQLKDNKSLGWQFVDEKTALEGVKKGTYYASLKIPKNFTKDLTSLITDDVKKGEI
                     IYTVNEKINAVAPKITDKGASTIQLQVNQTIVKTVSEIVLGISNGVGAGIEHSLPKLT
                     KVENSLIDLQKRFDHINKTVDLASDATSKLSDTVKDIKSDLPTIKKTLNDTKLLSSDL
                     KKFLEDTNDNLDELSPLIKSDLNLMVDLSSSASSLTLNLIDAVNSGSEDVPKLIDNLS
                     EKLSNLQSLNDTLVDFLTKLNQLTSNNRLDDVIDNLEDSSNKIDSSISTLNDIKNKVI
                     SGQQPSISALNNVLSLSNGIGRINLNILNNFDSKISKPINSIFANSIKVANDIITVLD
                     KAEAKLPKVEEILTTSLKLSGNAQESISLIRERLPLAKGMLDDLIDTLSKISNGEDMK
                     KLVSLLESDILTKSNFLKEPVEVKTEKLYPIENYGSAMTPFYSVLSTWVGILLISALL
                     STSVHGNYKPYEIYFGRGLTFLSIALVQGFIIGTGDILLLGVTAKHPILLIVLLMFTS
                     MVFNFIVYSLVSVFGNVGKAIAIVLLVVQIGSSGGTFPIQVTPTFFQRINPIMPFTYA
                     IGATREAVGGIYAPNLTKDILVLLLFMILSICLNVLLKGPINRVIKPFNDKFGDSNLT
                     GH"
BASE COUNT        76855 a        22984 c        33030 g        66310 t
ORIGIN      
        1 ataaaaaaga taataatagt tagatttttt atatgaattt taataggtaa aatatcctat
       61 tgttttgtag atatatccta attatgtcaa aaaataaaaa aatttttatt tattagagtt
      121 tttggaaata ataataacag atattataat taattaacag tttttgtaag tatttgacaa
      181 tagagagggt gtaacaaatg ggaataatag agtcagcatc aaaattggct gagatggttc
      241 atttattggc tgttgaaaag gggataactg atatagaagc atgggatgaa gctgtgaaag
      301 aatacagcaa aatttatgaa gaaagaagaa atgaatagaa tgataaaaaa tgaaaacttg
      361 atgataaaaa ataactttat ttaaagaaat tcaattttta tagaagtatt aaaaataata
      421 taaataaaaa gatggtattt caaatgtaag taaaaaatca ttttgggata ccatccttat
      481 tatttatttt aataatatat aagtaataaa tcttacttat ccatattttt tatgtaacct
      541 cttttttcta gcttttttat atgctcctta cgtatttcat caagattaat accatattgt
      601 tcttctagct taaacatcat agtaacacat gtctgcgcta catccattag ttccttagca
      661 gttttcttta taatatcaac ttcatctaaa tcattatttt ctccacttag atttctgaat
      721 ttacctatac attcagctaa ttcaccttgt tcttcaccca ttttgataaa tgtagattct
      781 agtgttgggt ctaaattatt aagctctggt aaagatatag tttttagttt cataaaagct
      841 cctttcaagt tattcgtatt tatactaaaa catcataaca aaaataatac taaaaaaaaa
      901 ctttaaattc aacataaaaa cttacatata taataaaaat catgaaataa atctatattt
      961 gtcttaatac agcctcatat aaaacttctc caataggttt atttattaca agagaggctg
     1021 acttatcata gactgtattt gctttattaa taagagcaat ataatcacct ttgtaataat
     1081 ctataaaact tgctgctggg tatacagcta atgatgtacc tcctataatc aataaatcag
     1141 cattacttat agcagaaatt gttttagtaa tgacatcact gtcaagagct tcctcataaa
     1201 gtactacatc tggttttact atagaaccac agttgtcaca gtaaggaata ttacctccca
     1261 gatttaacat agattctaag tcaaaaaatt taccacattt agtacaataa tttctatgta
     1321 cagaaccatg aagttctagc acatttttac ttccagccat ttgatgaagt ccatcaatat
     1381 tttgagttat gacagcttta agcttaccca tttcttcgag ttttgctaaa gctatatgag
     1441 cattattggg ttttgcatta ggatatatta atttatcctt ataaaattca aaaaattctt
     1501 ctggatatct aacaaaaaaa gtatgtgaaa ctaattgttc agcagtaaat tgtttattga
     1561 gtttttggct aaataatcca gtagaacttc taaagtctgg aatattagat tcagttgaaa
     1621 cacctgctcc accaaaaaat acaatattat tgtgattagc tattaagtct tttaagctat
     1681 ttgcatccat agttacacct ccaaattatt atatataaat tgtactacat attaggtcgt
     1741 ttatgtttta ttaatttaaa taaatatata gtttaataag ttaaataaag ggaatataaa
     1801 taaaatgtat acagagtata aatagacaat atttactaaa ataacaagtt gtcgtataat
     1861 tatattaaaa ttgttttagt gtataagaag ggcgggggaa gtacgtgaag aaaaaagcag
     1921 ctttagcaac attggctatg ttacccttag gtgtggtaaa tgcacatgct gatggagata
     1981 taggtatagt gactataaat tatttaaatg taagaaatga accaactgcc gaaagtagca
     2041 tagcctttgt tgctaaaaaa gatgataaag ttttgattaa agactcttct aatggatggt
     2101 ataaaataaa agctgaatct ggacaagaag gttgggcttc atcaaaatat atagcaaaat
     2161 caaatagtga ctctttaaga acatctacaa ataaagaaaa acaagttatt tcaaatagtt
     2221 taaatatgag aaatggagca ggtacaagtt acagagtaat aactgtacta aaaaaaggtc
     2281 aaaaagtaga agtaatatca gagagtaatg gatggtctaa aatcaaatat gatggaagac
     2341 taggatatgt atctagctct tatttaggag acgtttcaaa ctcaactaat aaatcaaaaa
     2401 ctaaacaagt gaatacaact tcactaaatg taaggagtgg accaaataca agttatggtt
     2461 tgttaggcaa gttgccaaaa ggaagtaaag tagaagtaat atcagaaagt aatggatggt
     2521 ccaaaataaa gtataatgga aaagatgcct atgtatctag tatgtactta tcggatgtaa
     2581 gtcaaagtaa ttcagacaat tctagtcaaa gcaatgataa aaagaatact gataaggttg
     2641 taaatacagc ttctttaaat gtaagaagtg gaccaggttc tacatatagt aagttgggaa
     2701 aagtttataa aggaagtaaa gtaactgtac tatcagaaag tagtggatgg gctaagatta
     2761 attttaacaa taaagaagca tttgtagtag gcaattattt atctacttca gcagatactt
     2821 caaataataa ctcaaatagt aactctgata gcagttctaa tagtaatggt aataattctt
     2881 catcatcagg tcaagtaaat ggtatgtcag gtataagtgg ggctaaaatt gattataaat
     2941 ctttgagtta tactttagaa tctcatataa gtaaacaagt tgagaaagca gcatcaggag
     3001 gaaatgtgat agctccaagt aataggaaaa gcactccaag tcctgaattt agtacttttt
     3061 cagctcaaag aacaagctca tttgtaaatg caagttcaag tgatatagaa tattatttaa
     3121 atcctaaaaa ttttacaaat actactaaag gtatgatgca gtttttaaag attaacagtt
     3181 atagagatgg tatttcagaa tcaagtctta actcgtatct taatggttta tcttctagtg
     3241 tatttaaaaa ccagggagca gcctttataa atgctgccaa gaagtataat atagatgttg
     3301 tatatctagt atctcatgct atgtgggaaa ctgcttatgg taagtctaca cttgcccaag
     3361 gtcaaacatt aacatcttat aagggacaac ctcttagtaa gccagttaaa gtatacaatt
     3421 tttttggtat aggagcaata gataaaagtg ctaatgtttc aggtgcagaa gcagcgtatt
     3481 ccaatggctg gactagtgta gaagctacaa tagatggctc tgcaaagtgg atatcacaaa
     3541 attacgtaaa tagttctaag tacaatcaga atactattta caagatgaag tggaattatg
     3601 attatacatg gcatcagtat gcaactgatg taaactgggc taatggaatt tctggaatta
     3661 tggaaaattt aattggtctt tatggaggag gaagtagttt ggtttttgaa gttcctcaat
     3721 ataagtaata cataaataaa aaatatagac tatgggtagt tttcatttta tttaaattat
     3781 ctatagtctt tttgtatata atttataatc tgtaaattta atgttaacaa aacttttatg
     3841 ttataatatt aattctaagt aaatataagt gagtaatagg tagaaataga taaaaagtgg
     3901 taataatata tataaagata attttgagaa aggaggatat atatggaaag tattaaggaa
     3961 tatttggata agttagaaat taataatagt ggtcttggaa agcaacttaa agaagtttat
     4021 ataaatagag tagtttattt taaggaagat aagatagttt atttttatct aacttctaaa
     4081 gatattgttt ctcatgaact tttagataaa tttaaagaag aattgatgta taaactcgat
     4141 tattttaaag atatgaggat gaagataaga tttactggtc ttgaaagaaa atccaataaa
     4201 gatgttataa aaaaatattg gaataatata ttgtatatat taaagtatct ttgtccatct
     4261 attgcagggt ggtataaaca agtagaattt ctttgtttag aagaagaatt aaaaataaaa
     4321 cttccaaaag gtatatttta tgagcgatta atgaaaaaaa atgtaactta tgtacttaaa
     4381 accgtgctta gcgaagagtt gggattagat ttaaatataa caatagaaaa agctgttgat
     4441 gaaaaggtaa ataaagaaag actcataaga atcaatgata gagaaatgga agaaaaaatt
     4501 agggctttag aaattggaaa agttaataac tgtgaagaaa atgaagagga aagctatgtc
     4561 attaagtctg atgtagatga aaatttaatc tatggagata atgcaaatgc tatgattgaa
     4621 aatatagttg aattaaatgc atcttctgga acagttgcag ttgttggaga tatatttgat
     4681 gttgacacta aagaacttaa aaacggaaaa atacttatga tagcttcaat tacagattat
     4741 actagctcaa taagctgtaa acttttttta acagatacaa ataaggatgg agtacttgaa
     4801 aatgttaaaa aaggagcata cttaaaaatc aagggtgaca tagtttatga tacatatcaa
     4861 agagaaatta gtatgatgat tagtgggata agaaaagaaa ctagaataga gagagaagat
     4921 aaatcagagg aaaaaagagt agaactccat gcacatacac aaatgtcttc tatggatgct
     4981 atttgttctg ttaaaaagct tgtagagcgt gcagccaaat ggggtcattc tgctattgct
     5041 ataacagacc atggtgttgt acaaggattt ccagatgcta tgaatgcagg taagtcaaat
     5101 aatataaaaa tactttatgg agtagaaggg tacttggttg aagatgattc tctcattata
     5161 gaggatgcaa atgataaaga actttcgcag acatttgttg tatttgacat agagacaact
     5221 ggtttttcta atacaaatga taaaataact gagattggtg ctgtaaaaat agaaaacttt
     5281 aagattgtag atagatttag tgagttaata aatcctgaaa aagatatttc ttataagata
     5341 caggaattga caggaataac taatgaatta attaaagaca agccaaccat tgaagaagtt
     5401 cttcctaagt ttatggaatt tgttggagat agtgtattag tagcgcataa tgcagagttt
     5461 gataccggat ttatatcgca aaaatgtagg gaacaaggct tgttatataa taacaaaaaa
     5521 gtagatacac ttatgttagc aagagtaatg ttgccaaact taaaaagaca tagattaaat
     5581 gtcgttgcaa aagaacttgg tattcctctt ttaaatcacc atagagcagt ggatgatgct
     5641 gaggctacag cacttatatt taataagttt ttgcagatgc ttacagaaaa aggtgcaaaa
     5701 actctaagtg atgtaaacaa tatacttgga aagattgatt acacaaagct tagcacaaat
     5761 catataacct tgatagcaaa aaattctata ggtataaaaa atttatataa aataatttca
     5821 gatgcacatg taaatcattt ttttagagca ccaagaatcc ttagaagtgt attaaatgaa
     5881 tataaagaag gattaataat tggttcggct tgtgaagctg gggtggtttt tcaagctgta
     5941 aagaaaaacg tgtctgatga ggaaatgaaa aaaataatag atttatacga ttatattgaa
     6001 gtaatgccta tagataataa tagatttatg attgataaag gagaagtaaa ggatgaagaa
     6061 gagttaaggg agttgaatag gaaattaatt gatacagcca aaaaatttga caaaattcca
     6121 gtagctactg gggatgttca ttttttagac aaacatgaag ctgtcttaag aaaagttctt
     6181 aaatattctc aaggttttaa agtagatgaa gaagaaactt atttacattt tagaacaaca
     6241 gatgaaatgt tggaagagtt tagttatctt ggagaagaat tggcatatga agttgtagtt
     6301 gaaaatagta atctgattgc cgatatggtt gaagatataa aacctatacc agatgatact
     6361 tatcctccaa ttatagaggg ctcagatgtg gagttaagag aaatgtgtta caaaaaagcc
     6421 aaacgaatct atggagaccc aataccagaa atagttcaaa aaagactgga tagagaatta
     6481 aattcaataa taagcaatgg gtatgcagtt atgtatatta tagctcaaaa actggttgca
     6541 aaatctcttt cagatggata tttagttggt tcaagaggat cagttggctc atcttttgca
     6601 gctactatga gtgatataac agaagttaat cctcttccag cacattatat ttgtgaaaac
     6661 gaagactgta aatattcatt cttttatgaa ataggtgaat ggggctcagg tgttgattta
     6721 ccagacaaag attgtccaaa gtgtggaaga aaacttgcta aaaacggtca tgatattcca
     6781 tttgaggttt tcttaggttt tgaaggtgat aaggaaccag atatagactt aaatttctca
     6841 ggaaattatc agccaacaat tcataaatac acagaagaac tatttggaga ggggtatgta
     6901 tatagggctg ggactatagg tactgtagca gaaaaaacag cttttggata cgcaagaaaa
     6961 tatgtggaag aaaataatat aagtgtacca aatgcagaag tacttaggct ttcaaatgga
     7021 tgtactggag taaaaagaac ctcaggacaa catcctggtg gagttatggt tataccagac
     7081 tataaagatg tatacgattt tacacctata cagtatccag caaatgatac ttcttgtggt
     7141 gttataacta ctcactttga ttatcattca ataagtggta gaatacttaa acttgatata
     7201 cttggacacg acggtcctac cattataagg atgcttgaag atatgactgg aataaatata
     7261 acagaaattc ctttagatga taaagagact atgtctctat ttacatctac agaagcatta
     7321 ggtgttacac cagaagagat aaactgtcct ataggttgcc ttgctgtacc agagtttgga
     7381 actaagtttg tacgacaaat gttacttgac acaaaaccta ctacatttgc agaacttgta
     7441 cgtatatctg gtctctctca tgggacagat gtttgggtaa ataatgcaca agacttagtt
     7501 agagaagata tagttggatt aaaagatgtt atatctacac gagatgacat aatgaactat
     7561 ttaatattta aaggattacc tcccaaaatg agttttacaa taatggagag cgtaagaaaa
     7621 ggtaaaggtt taaaaccaga acacattgaa gaaatgaaaa aaaataatgt tccagaatgg
     7681 tatataggct catgtaaaaa gattaagtac atgttcccaa aagcacatgc tgttgcttat
     7741 gtaatgacat catttagaat tgcatattgt aaagttcact atccagaagc attttatgcg
     7801 acttatttta cgacaaaagt tgaggatttt gatgcagatt taattgttaa aggattagat
     7861 gctataaaat caaaaataaa tgaaattgag tcactgggaa atgatgcaac cacaaaagaa
     7921 aaaggtatgt tgaccgtttt agaagttgct cttgaaatgt atgctagagg aataaaatta
     7981 ttaccagttg atatatataa atcagatgca actgagttta tagttgtagg agaaaaaaca
     8041 ttacttccac caatggcagc aatacaaggt cttggaggaa atgcggctat aaacatccaa
     8101 aatgaaagaa aaaatggtga atttatatca aaagaagatt tgagaaagag aacaaaaata
     8161 tcaaaaacgg taatagaaac tcttactaat catggttcac ttgagaatat gagtgagaga
     8221 aatcaattgt cattgtttta agttagccca aaaagttgca aataaaagaa ttttatgata
     8281 tcatagtata gaaaatagta tactttgcag aaactaagag tgagacagct gttctcactc
     8341 ttttatttta aatatattat taaaaagctg gtttattttt attaaatata ttttatttaa
     8401 gattatataa actggtcatt tacaattgaa taggaggaac tttaatgaaa aaaaatttag
     8461 aagctacaat tgaggagatt gtaactaaaa taacggatga acatggattt gaaatggttg
     8521 atgttgaata tgtaaaagaa gcaggagaat actacttaag agtatacata gataaagaag
     8581 aaggaatatc tttaaatgaa tgtgaattag ttagtagaga attaagtcca atactagatg
     8641 aaaaagaccc tataaaagaa aattactttt tagaggtatc ttctccaggg cttgatagag
     8701 cattaaaaaa agacagagat tttgttagat atcaaggtag agatgtagat ttaaaattat
     8761 ataaaccatt aaatggatgt aagcaatttg aaggtgaact tgtaggatta acagaagata
     8821 ataatataaa aatcattgca aatggtaagg aaatggaatt taatagaaaa gatgttgcta
     8881 ttgtcagatt agcaataaag ttttagtggt atattaaata gggaggatat aaaaaatgaa
     8941 tcatgaattt atggaagcat tagatgaatt agtagttgac agaggtatag ataaagaaat
     9001 acttatagat actatagaac aagctctttt aactgcatac aagaaaaact ttggttcagc
     9061 acaaaatgtt agagttgaat ttgatagaga caagggagat ataaaagtat tttctcaaag
     9121 agttgttgtt gatgaatcag atttatatga tactttctta gaaatagagt tagcagatgc
     9181 tagagagata aaccctaatt atgaattagg tgatattata gaacatgaag ttacacctaa
     9241 aaactttgga agaattgcag ctcaaacagc aaagcaagta gttgttcaaa gaataaggga
     9301 agctgagaga gaaatagtgt ataatgaatt tatagaaaaa gaaaatgaaa tagttacagg
     9361 agaggttgct agagcaaata aaaatgttgt ttatgtaaat cttggaagaa tagaaggtat
     9421 aatgactcaa agtgaacaaa taccatttga gaattataaa gcaggtcaaa aaataaaatt
     9481 ctatatactt gaagttaaaa agactaacaa aggacctcaa atagttgtat caagaagtca
     9541 tccgggtcta gtaaagagat tgtttgaaga agaagttcct gaaatatatg aaggaatagt
     9601 tcaaataaaa tctgtagcaa gagaagcagg gtcaagaact aaaatggcag taagatctat
     9661 agatgaaaaa atagacccaa ttggagcttg tgttggacca aaaggactta gagtaaaaaa
     9721 tatagtggat gaacttggcg atgagaaaat agatataata aaatatagtg aagacccagc
     9781 agagtttata tcagcagcac ttagcccatc aaaggttgtt agagtagata tagatgaaga
     9841 tgaaaagtct gccttagtaa tcgttccaga ttatcagtta tcgcttgcta taggtaaaga
     9901 aggtcaaaat gcaagactag cagcaaaatt gactaactgg aaaatagata ttaagagcga
     9961 atctcaagca gaacaagaaa tgttaaatct tgaaaattcc aaagaaatag aagctgagga
    10021 tgttgaagct gaatttatcg accaagaaga gttagatact tcagaggata attttagtga
    10081 agaagagtaa ggagggatga ttttgaaaaa agtaaaaaaa gtgcctcaaa gaaaatgcat
    10141 agcatgtcaa gatagagact ctaaaaaaga gcttataaga atagttaaaa ataaagaagg
    10201 aaaaatattt ttagacccaa caggaagagc caatggaaga ggagcatatg tatgtaaaag
    10261 ctctgaatgt ctaaaaaaag ctataaagag taaagcatta aataaagctt ttaaaataga
    10321 tgttcctgat gaagtctatg ataatctact tatggagtta gaagaatatg aaaaataata
    10381 aagaaaaagt actttcgttc ttagggctcg caactcgtgc agggaaaata gtgtctggtg
    10441 atgattcaac tttgcttgac cttaaaaaag gaaaagtaaa tttgatttta atcgcagaag
    10501 atgcatcaaa taatactaaa aaacttttta aagataaatc aacttttaga aatattccat
    10561 atctattttt ttcaacaaaa gaggaaatag gatttgcaat aggaaaatct ccaagagcag
    10621 ttgtaggaat aaaagatgaa aatttttcta aaaagataat tgaactaata gaaatttaaa
    10681 ataaaatagg gggtgatctt gtgtcaaaaa caagagtata ccaaatagca gaagaattaa
    10741 atatatcaaa tgaagagctt ataaataagt tagctgaatt agatataaat gtaactgaca
    10801 aagattcagt attagaaggt gaagagttag aattagcact tgaaatgtta ggtgaagatt
    10861 tatctcaaga aaatggaaat gttatagaaa tagatggaaa gttgacagta caagtattag
    10921 caacgaaatt agataaatct ccatcagaaa taattatgaa gcttatgaaa atgggaacta
    10981 tggcaacaat aaatcaagag ataagttttg agattgctgc tttggctgcc aaagactatg
    11041 gatttgaatt aacagtagct gaaagtgatg atacagaagc tttagaaata gaagctttaa
    11101 tggaaattga agaagataaa gaagaggatt taaaacctag accaccagtt gttacagtta
    11161 tgggacatgt tgaccatggt aagacatctt tactagatgc aataagaaaa actgatgtga
    11221 tttcaggtga agctggagga ataactcagc atataggtgc ttcagaagtt aaaatcaatg
    11281 gacacaaaat agtattttta gatactccag gacatgaggc tttcacatca atgagagcaa
    11341 gaggagcaca agttacagat atagcaatat tagtagttgc agcagatgat ggtataatgc
    11401 ctcaaacagt tgaagctata aaccatgcta aagcagcagg tgtaccttta atagttgcta
    11461 ttaataaaat agataaacca ggtgcaaacc cagataaggt taaacaggaa ttagcagacc
    11521 aaggattatt agttgaagac tggggtggag aagtaatagc agttccagta tcagctaaga
    11581 aaaaagaagg aatagataca cttttagaaa tggtattatt ggttgctgaa atggaagagt
    11641 taagagctaa tccaaataaa agagcagtag gaactgttat agaagctgag cttgataaag
    11701 gaagagggcc agttgcaaca gtacttgttc aaggtggtac tttaacagta ggtgacccaa
    11761 tcgttgcagg tgttgcatgt ggtaaagtta gagcaatgat aaatgcaaaa ggtaagagag
    11821 taaaaacagc aggaccatct acagcagtcg agatattagg tctatcagaa gttccacaag
    11881 gaggagacca atttgtcgaa gttccaactg ataagattgc tagaagtgta gcagcaagaa
    11941 gacaacaaat agttagagat gaaatgttaa aatcaactca aagattatca ctagatgctc
    12001 tatttagtca aatgagtgaa ggttctataa aagaccttaa tatagttata aaagcagatg
    12061 tacaaggttc agtacaggca gttaaacaat ctttagaaaa attatcaaat gaagaagttc
    12121 aagttaaagt aatacatggt ggtgttggag ctgtaacaga atcagacata ttacttgcag
    12181 cagcttctaa cgcaataata ataggattca atgtaagacc agttccaggt gcagaatctc
    12241 taggagaaaa agaaaatgtt gatataagaa catatactat aatatacaag gcaatagaag
    12301 atatacaagc ggctatgact ggtatgttag accctgaata tgttgatgaa gaaacaggaa
    12361 aagctgaaat aagagaaata tataaaatat ctggtgttgg aacagtagct ggatgttatg
    12421 tgactaatgg taagatattt agaaattgta aagtaagatt agttagagat agcataataa
    12481 tacatgaagg tgagcttgca gcacttaaga gatttaaaga tgatgtaaaa gaagttaatt
    12541 ctggatacga atgtggtatg agttttgtaa attataacga cataaaagaa ggcgatatag
    12601 tagaagctta tataactaaa gaagtagaaa gaaaattata aattcgtatc aaagaaaatc
    12661 agttagtaaa gaaggtcgat ggtatggcat catataatag aacaagaagg atagcagaag
    12721 aaataagaaa agtcgtaagt actatgctta taaatggagt aaaagaccct agaataacat
    12781 ctatggtgag tgtaactgat gtagaagtta caaatgacct aagatatgct tatgtatatg
    12841 taagtattct aggtggggat gaagaatcca cactaacagg tcttaaaagt gctggaggat
    12901 atataagaag agaagtagga aaaaatataa aacttagata tattcctgag atagtattta
    12961 aacttgatga ttcaatagaa aaaggaatgt atatggatag ccttataaaa agagttaatg
    13021 aaaaagatgc tcaacaaaat gaggatgaaa attatgatga ataatatgga tagtattata
    13081 aactatattt atgagggtga ctattttata gttacctctc atatcagtcc agatggagac
    13141 aatattggtt ctacactttc aatgtattat acattgaaga atttaggaaa aaatgtatat
    13201 tatgtacttg atgatgaagc tccattaaat ttaaggtttt tggttgaagg tgtaaaaatc
    13261 tataagtcta atgaatttaa tatgaagaac tattctctaa ttgcacttga ttgtggggat
    13321 aagatgagaa tatgtgtgag tgatgaaatc aaaaataatg catcaaaatt aatctgtatt
    13381 gaccatcatg ctagtaatga ttcatatgga gatttaaatt atgtagatat tgatgcatct
    13441 tctacatgtg aattagttta taatttatta gttagatttc agcaaataaa agatattaat
    13501 attataaatg aagatatagc aacatgttta tatacaggtc ttgtaactga tactggaaac
    13561 ttttcgtatt caaatgtaca tgcaagtagc tttgaaatgg caaaaaattt acttgtttta
    13621 ggtgcacaaa aaaatactat aatacaaaat atatatcaaa gcaattcctc tgattattat
    13681 aaattattag gagaagctct aaagggtttg gagatatttg attcaaaggt atctagtata
    13741 gttttaactc aagacatgat gaatagaaat aatattagct ttaatgatgt tgatggaata
    13801 acaacatata caagagatat aaaaggtata gaagttggaa ttttatttaa agagaaaaaa
    13861 caaaatgaaa ttaaagtgag ttttaggtca aaaaattatg ttgatgtaag tgaaatagcc
    13921 aagttatttg gcggtggtgg tcatgtaagg gctgctggat gtactattag agatagtatt
    13981 gataatgcaa agaaaatggt actagaggca gtgttaaaat caatttaagg tgacagtaaa
    14041 atgaataaga ttataagtat attgaaaccc acaggtatga catctcatga tgttgtaagt
    14101 agagtgagaa agattctaaa tataaaaaaa gttggtcata caggtactct tgacccagat
    14161 gcttcaggtg ttttaccaat ctgtataggg aaagctacaa aagtatgtga agttatttta
    14221 aacaaagata aatcgtatat atgtgagctt actttaggta taagtacaga tacttatgat
    14281 gcttcaggtg aaattttaaa aaaagttgat gattttaaat ttagtaatga agacatagaa
    14341 agagcttttg acacacaaag aggagagata aatcaacttc ctccaattta ttcagcttta
    14401 aaggtaaatg gaaagagaat gtgtgattta gtaagaagtg gtagacaatc tgaaattact
    14461 ttaaaaacaa gaagagtaaa tataaaagac ataaaaatac taagtataaa aggtaataaa
    14521 gtaatgtttt atgttgagtg ttctaaaggg acttatgtga gaagcatttg ccatgatata
    14581 ggagaatatc taggttgtgg agctcatatg tcgtttttga atagaacatc ttctggtaaa
    14641 tttgacttag ataattcaat aacattagaa gaattagaat tattttatga aaataaaact
    14701 ttagacaaat acttatatga tatagattat gtccttgatt cgtttaatta tgttgtatta
    14761 aaccctaatg ctataaaata ttatagtaat ggtggctcaa tagatgataa aaggttttta
    14821 aaaaataatt tcgataaaga tgatgaattt gtaagagtat acagtacaga taatttctta
    14881 ggattaggaa aattatcaaa acacaataat acaataagtg ttaaaagtga taagatgttc
    14941 atataaccaa tgtatttaaa aaaacaacaa aagagatagt actataataa cttctatagt
    15001 ctatctcttt tacttatgct ataatagttt gtgaataagt taagagtaaa ttatatttta
    15061 gcggggaaca tttattatgg tgattataaa atctataaaa gaaatagcaa acataaaaga
    15121 aagtgtcatt accataggaa attttgatgg tgtacacaaa ggacatcaag ttcttatagg
    15181 aaaaacagtt gaacatgcaa aaaaagaaaa tatacagagt atcgtattta catttgcaaa
    15241 tcatcctgta aattacttta gaccaaactc aacaaaaaat attataagca atgatgataa
    15301 aataaaatta ttagaagatt tgggaataga tatagttgta atcataccat ttgatgagta
    15361 tatgactaaa atacctgcaa aggatttcgt agatgagata ctagtaaaaa aattaaaagc
    15421 taaaaagata gtaattggac atgactttac atttgcaagg gcaaaagaag gcaatgttaa
    15481 tctattaaaa agcttagaac atgaatttgg ttttgaggta gaagtaataa aacccatcaa
    15541 aatcaatgat gtaagagtga gtagtactta tattagaagt ttagtatccc agggtgatat
    15601 ggctaatgtc aaggaatatt tgggtagaaa ttacaagtta gaaggttgtg ttatacattc
    15661 taaacacctt ggaagaacta taggattccc aacggcaaat attgacctta agaataatat
    15721 gctcgttcca aagagaggta tttatgcttc tattgtacat attggagatg agacttattt
    15781 tggtgctaca aatgtaggct ataacccaac agttaatgga aaaactttgt ctattgaaac
    15841 aaatatttta gagtttgata gagatattta tggggaaaat ataattgttg aatttttgga
    15901 aagaataaga gatgaaagaa agtttaattc aatagatgac ttaaaaaatc aattgtataa
    15961 tgatacaaat tatgtgtatg aaaactatgt ttgcaaaaac aagtaatgta tgataaaatg
    16021 attaaggaaa ataaccatta ctcggcattt gaatactcca atcaatgctt agtaataggc
    16081 gtttctaaaa aaatacggag gtaatctaaa tgataaacaa atcagaaata ataaaagaat
    16141 atggaagagc tgaaggggat actggttctc cagaagtaca aatagcttta ttaacagcta
    16201 gaataaacga gttaaatgga catttaaaaa ctcataagaa agaccaccat tcaagaagag
    16261 gactattaaa aatggttggt agaagaagaa acttattagc ttacttaaag gaaaaagatc
    16321 ttgaaggata tagagcatta atagctaaat taggattaag aaagtaattt cattctttat
    16381 aaaaaagcag gtatagtgta tacctgcttt tttatagtta attcattata aagtaaaata
    16441 gttaataata aaagtagttt atatgttata aaaaattata aaatgaataa tattgggtaa
    16501 gaatattaaa atagtataca aatacataat caatttaaaa ggaaagacag gataaatata
    16561 gaaattttat aacaggataa ttagttggaa taaggaggat attattttga aaataaagtt
    16621 agtatgcgat agtttgtgcg atattccaga tgaaatatca gaaaaagatt atatagagat
    16681 agttccactt acagttattt ttaatgatag ggaatatata gaaggagtag atataaagaa
    16741 agaagagttt tataaaaaag taaaagaaat caagcaaata cctaaaactt cacaagctac
    16801 atatatggag tttaaagaag tgtttgataa gttcataaca gaaggttatc atataatctg
    16861 tatgacaggg gctgcaaacg catcaggaac ttttcaaagt gctatgatag ctaaaaatga
    16921 tgtaaatgaa aatgaaaaaa tacatatatt tgatactaga aatttatctc taggtagtgg
    16981 acaatatgtt ataaaggcat gtgaacttct tgaagaagga ctgggatttg aagaaattat
    17041 agatgaatta gaaaatactc gcagtagtgt aagattgctt tttgcaccat atacacttga
    17101 ttttttaaag cagagtggaa gagttccagt tgcaactgct ttgataggaa atatgttaaa
    17161 tataaagcct atatttttct ttgataatgg ggaagctaag ttggtaaata aggttagagg
    17221 aataaagaat atagcaagta aattggtcga tataatttta gaaatgaatg aagggtcttt
    17281 agaaggaaaa atcgtcacaa taggttgtgg agataattta cacgattgtg aaatattaaa
    17341 agatgaagta aataaaagaa taaaagcaag aagagtatta tttactcgag gaggagtttc
    17401 tatttgctct catacagggc cagatatatt ggctataagt tgttctaatt agtagtaata
    17461 taaggttttt gcatatatat gtgaagataa ttttatattg ttaatttata gtatttttga
    17521 taatatagta aatagagtga tatacgtgtt ttttaataag aggaggacaa gcattaatgt
    17581 ttgaacataa aatatttaaa atggattttg caggaagaga actttctgta gaaataggaa
    17641 agatttgtga aatggctagt ggtagttgta tagttcgata cagtgatagt atggtaatgg
    17701 taaatacaac taaatcagcc aaacctagag acggaataga cttttttcct ttaagtgtgg
    17761 attatgaaga aaaattatac tctgtaggta agatacctgg aggtttttta aagagagaag
    17821 gcaagccttc agagaaagct atacttacat caagattgat agatagacca ataagacctt
    17881 tattcccaaa aggatttaga aatgatgttc aggtagttgc aacagttcta tcagtagacc
    17941 aagattgtac accagatata gtagcaatga taggttcttc aatagccctt tctatatcag
    18001 acataccatt taatggacca acaggttcag tatgtgttgg ccttgtagat ggtgcatttg
    18061 ttgtaaatcc aaacgcagag caaagagaaa aaagttcaat gcatctagtt gtttcaggta
    18121 caaaggaagc aataatgatg gttgaagccg gagctgatga agttccagac gaggtaatgc
    18181 ttgatgctat tttatttgct caccaagaaa taaaaaaaat agttgagttt atagaaggta
    18241 tagttgcaga agttggaaaa gaaaaaatgc ctgttgaatt ataccatgca ggagaagaaa
    18301 taactcaatt ggttcgcgaa tttgcaactg ataagatgaa aaaagcagtt cagacttttg
    18361 aaaagttaga gagaatggaa aatatggata gagttaaaga agaaacttta gctcactttg
    18421 aagaaacttt agaagatttt gaagattttg ttggagatat agaagaagta ttacaagata
    18481 taataaaaga agaagtaaga aaacttatag tacatgaaaa tgtaagacca gataatagaa
    18541 aacttgaaga aataagacct atatggtgtg aaactggcat gatacctaga gctcatggtt
    18601 cagccatatt tactagagga caaactcaag tacttaatgt tgctacttta ggtgctttag
    18661 gagatgttca aaaactagat gggttagatg aagaagaaaa caagagatat atgcatcatt
    18721 ataatttccc tgcatatagt gttggagaag ctagaccatc aagaggacca ggaagaagag
    18781 aaataggaca tggtgcttta gcagaaagag ctttattacc agtaatacca tctcaagaag
    18841 aatttcctta tgctattaga ttagtttctg aagtattaag ttcaaatggt tctacatctc
    18901 aagcaagtgt atgtggctca acattatctt tacttgatgc aggtgtacct ataaaagata
    18961 tggttgcagg tatagcaatg ggacttataa agcatgatgg taaggttgca gtgctttcag
    19021 atatacaagg tatggaagac catttaggcg atatggactt taaagtagct ggaacagagt
    19081 atggtataac agcaatacaa atggatataa aaattgatgg tatagataaa gaaattctac
    19141 aacgtgcttt aaaacaagct aaagagggta gaatccatat actaggagag atgagaaaaa
    19201 ctatatctca gccaaaacca gaactttcac catatgcacc taagattgtt aaaatgcaaa
    19261 taaatcctga caagataaaa gatgtaatag gacctggtgg aaagataata actaagataa
    19321 tagacgaaac tggagttaag atagatattg aacaaactgg ggaagtattt atatcaggta
    19381 ttgagattga tatgattaag aaagctcaag aacttataaa taatatagta gttgaaccag
    19441 aagtaggaaa aacttataaa ggtaaggtaa gtagaataat gaactttgga gcatttgttg
    19501 agatacttcc aggaaaagaa ggattacttc atatatctca tatagctcat gaaagagttg
    19561 ccaaagttga agatgtattg aatatagggg atgaagttga agttaaagtt acagagattg
    19621 atgaaaaagg aagagttaat ttatcaagaa aagttctttt accaaaacca gaacataaaa
    19681 ataaataact tattatataa ttaaaagcaa agtcttagga ttttgctttt ttaaatacaa
    19741 aaaagtagat aattttaaaa tgatagttat ggatggctta tagttctttt tctgtcaggc
    19801 tttactctta taaagaagct atttaaaagc tgattaatag agagctttat tgatatatat
    19861 agaatcactt aagttatatt tagtgcataa acagagctta tttttaatag tattaaataa
    19921 gaaacaattt gtacataatt agggggagtt ttaatgataa tgatggtact taataagagt
    19981 aagctcaaaa aaatcataat actaatttta gtagtgttat tagtattatc aggaggggta
    20041 atggtattaa agttatttaa caacaagcca gtatttaatt tatttaatgg tgtagattta
    20101 ccatatgaaa gaggtacaaa ggataaaagt ggatatgttg cattaacctg taatatagac
    20161 cttggatggg aaacagagta cgtagaatcc attttagaaa cacttaaaaa agaaaatgta
    20221 aagattacat ttaatgtaac tggaaaatgg gcagaaaaga ataaggatga attattaaag
    20281 ataaaaaaac aaggacatga aataggtaat catggataca aacatttaga ttattctaca
    20341 ttatcatatg aagacaatta tgagcaaata gagacctcta aaaagataat tgaagaaatt
    20401 ataggtgaaa aaactaaatt ttttcaagca ccagcaggtt cttttggtcc agaaacagta
    20461 aaggctgcta aagcattagg gtatacttct atcaaatggg atgccgatac tatagattgg
    20521 aaatacaaag accaaccaga ggtaatcatt gatagaatga agaaaaaaga cattaaagat
    20581 agtagtataa ttttaatgca tccaaccaac gcaacgacaa aatgtataga tgatattata
    20641 gctattgtaa gagaaaaagg actaaaacca ggaaaactta gtgatgtatt taagtagaca
    20701 aagtataaat atttggttaa gattgtataa gttgtagttg aattaattaa aagactgact
    20761 tataatgtaa tacatataaa aaataaatat aattaaaaca tagtgttttc aataatccaa
    20821 tatgaaacaa agaataaatt gttaggagaa tgtaatgtat aagacaaaaa tactggaaaa
    20881 tgggcttaca ataattggtg aagaaatacc atatctaaag tcaataacat taggtatttg
    20941 gataaatgca ggctctagga tagaagaagc acaggtgagt ggaacttctc attttataga
    21001 gcatatgatg tttaaaggaa ccaaaaacag aacatcaaaa gagattgcta gttcaataga
    21061 taatttgggt ggtcaaataa atgcatttac aagtaaagaa tgtacatgtt attatgtaaa
    21121 actaatagat gagcatatag atacaggaat tgatgtattg agtgatatga tactaaattc
    21181 taaatttgat aaaaatgata tagataagga aagacttata atattggaag aacttaagat
    21241 gtatgaagac tctccagatg acttatctta tgatttatta gtggaaaata tatatgctaa
    21301 tgatggatta ggaatgaata taattgggac aaaagaatct ctatacaata taactagaga
    21361 atccatgtta gaatacttaa ataagtatta tattccaaat aacgctgtta tttctatagc
    21421 tggaaacttt aactttgatg atatggtgga gaaaatcaaa tcaaaatttg gacactggga
    21481 aaagaaaaat ttaagtatag acataagtga ggctaagttt aatccttgct ttatatcaaa
    21541 aaataaagat actgaacagg tgaacttagc tatgtgccta aaaggtattc cttttgaaaa
    21601 tgatgaagaa gtctattcaa tggcagtggt aaataatatt ttcggtggaa gtataagctc
    21661 aaggcttttt cagaaaataa gggaagaaaa aggtttagta tattcaatat actcatcaca
    21721 gacattatat aggaaatgtg gtgaattagg tatatttgca agcatgagta cagaaaattt
    21781 acaagatgta tataatttaa taaagaaaga aattgaaaat ataagagaaa actatcttac
    21841 agaaaaagaa atatctgaaa gcaaggaaca gttaaaagga aattatatat tggatttaga
    21901 aagtactagc agtagaatga tgtctactgg taaatctatg ttacttagta aaaaagtaaa
    21961 aactacagat gaaatacttg aatgtataaa taatgttaat attaattcaa taaagaaggt
    22021 tgttgataag gtattcaata tcgaaaatat tggtacatgt atagttggaa gagatgtaga
    22081 aaagattcta cacttggatt aatattgaaa aaagtaaatc tctggaggta taaaatatga
    22141 atttatctga aatagcaggt aaggaaatag ttaacttggt cacaggagaa agattggggg
    22201 tcattggaga atgtgacctt atactagatg aaactacagg cggtatatta gcgcttctaa
    22261 ttccaaaaga aaaaggattt tttgccagaa gaaaagataa gtcattttta gaagtaccat
    22321 ggagaaatgt aaaaaaaata ggtaatgaca tgataattat agaatatgag ggatatattt
    22381 aggaggaaaa aatgagtatt ttagtgcaaa agtttggtgg gacatcagta gaatcatatg
    22441 aaaaaatgaa tgaagtatgt aagatagtaa aagcatacaa aaaaaatgat gaagaattac
    22501 aattagtatt agtagtttca gcaatgggaa gaaaaggagc tccatatgct acagatacac
    22561 ttataaattt gtgtagtgca gtaaatgatg agccaagtaa aagagaactt gatttaataa
    22621 tgtcttgtgg agaaataata tcaggaacaa ttcttgctaa tttattgaat gcacagggga
    22681 tagattctgt tttctttact ggtcagcaag caggtataat tacaagtgat gaatattcta
    22741 atgcaaagat aaagtatata aatcctaaaa aggtaaaaag agctttagat gatggtaagg
    22801 ttgtagttat agctgggttc cagggtgtaa cagatgatgg agaaataact actcttggaa
    22861 gaggcggaag cgatacatca gcagttgcta ttggtaaagc tttagaatgt gaaacagttg
    22921 aaatttacac tgatgtggat ggtataatga ctgcagaccc tagagtagaa ccaaacgcta
    22981 aagtattgag ttttatagac tatgaggaag tattccaaat ggctgacaaa ggtgcaaaag
    23041 taatacatcc aagagcagta cagttggcta aaagtggaaa tataacttta gccataaaga
    23101 atacaatgaa tccaactttt gaaggtacaa aaataggttc tttatgtaga cacttagaag
    23161 acaatataga atatgaacaa gaaagagatt ttaaggttgc tgttgcaaat aaagatagcg
    23221 tagcacaagt taagattaag tcagcagaag aagtgtttac agaagtatta aatgagatag
    23281 aaaagaaact tataactata gatatgataa atttctttat atcagaaaaa gcatttgttg
    23341 tagaagatgc tgatataaaa tcattaaagg aaatactaga taaatttgaa ttagattatg
    23401 aagtaaatag agactgtgct aaggtaacat tgatatgttc aagaattgct gatgaaatgt
    23461 ctggtatcat gtcaaaggta gttagaggat tatcaaaagc aggggtatct cttttacaaa
    23521 catcagactc aaatatgact atatcttgtt tagttagtga agaagatatg catacagcag
    23581 tacatgctat acaccaacaa ttttatttaa aataaactgt ataatacaat tattttttaa
    23641 tcaaatttaa gaatttcata tatatcttaa tatatttgat ttatttggta aaactaaatt
    23701 aaatataatt ttgataggag tttttttatg aaagattata gagaagataa tgaaagattt
    23761 gataaagata attgtagtga agaatctagt tgcgaagaga gagaatgtat aaagcaattt
    23821 ggtaccaatg aaatgccacc tcaacctcct aaagatattc aatgtataac tataattgga
    23881 gaaattgagg gacattttat aggaaatcct caaaaaaaag ctacaaagta cgagcatata
    23941 attccaatgc tatactcaat tgaggaaagc aatgatgtta aaggagtgtt agttgtttta
    24001 aacactgttg gaggagatat tgaagcaggt ttagctattg cagaactttt aaacagtaca
    24061 tctaaaaaag tagttactct tgttctagga ggaagtcata gtataggtgt tcctcttgct
    24121 acagcaggag attactcatt tatagcacca acagcaacca tgattataca tccagtgcga
    24181 actactggtc ttgtgattgg tataaatgag acttttgaat attttaaaaa gatgcaagat
    24241 agaataattc aatttataat aagaacatca aatatcaaaa aagatgtact tgaaaaactt
    24301 atgcatgaaa aagatgaact tgtaagtgat gttggtagtg tattaatagg aaaagaagct
    24361 gtggattatg gtcttataga tgaagttgga ggactaaaag aagcacttaa aaaattaaga
    24421 gagcttataa aagaatctga ggaagaaaaa aataatgatt aaaatttgtt taaataataa
    24481 aatttatgat ataatgatgt aataaagtag gagtgttagt gttaaggcat tagcactttt
    24541 tgctgtgaag gggtaaaact tgctaaaaat aaggagtgat attaatggcc acgaaaaaga
    24601 agaaaaaaaa gaaggtaaat accttaagtt ttaatgcaga atatcataat ttaataacaa
    24661 tatttatagg tgtattttta ttatatagtt taaattctaa ttctatggga tggatacctg
    24721 tgttaatgca aaatcttttt aagggactat ttggagggct ttcaatagca ataccattta
    24781 tagtaattat aacaggactt ttaggatttt ttgatggaaa tgaatatata tataggctaa
    24841 gaaagactaa actatactac ataattattt tatttatatt tgtattttat ggattattaa
    24901 atgcaggaac tcttcctgta gatagcccac taaaaggtaa tatgtttgat gatgttatga
    24961 aattgggtgt aagtggacaa ggtagtggtt tgatagcgac aactattgca tattatatga
    25021 gtaaaatatt tggtatagca ggtggatggt taataagtat cttcgcactt atactttctg
    25081 taatgtttat atttaatatt tctataaaag atttggtgtc aaatgcaaaa tcaaaatcta
    25141 aagcatctaa agacagcaat ttaacgttta aagataaaat tgcaaatatg aaaaaatctg
    25201 caatagatat gatgactgat gaagtagatg atactactat aaataaaaaa ccaggtttct
    25261 ttaaagggtt aatgtcaaaa ggtcttaata atgatgatga agaagatgaa tattttgaag
    25321 aagaaaatag tgatggtgta gatgataaaa ctataaaaat agttggattt aataaggcag
    25381 aagatgagta tttagaaata ttagaaggaa ctcaaagtat gccagagtta gatgttttaa
    25441 aagaattaca aaaagctacc aatgaaaatc cagttgtaga tactaaacca gaaaaaaaag
    25501 ttgatatagc taaacctaat ttaaatatag aaaaaactca acctatgagt attgtagcag
    25561 agccagttaa tgaggattat tcaaactata aaaagcctag cattgagctt ttaaataaag
    25621 taaataagaa gtctgatgaa aatggtaaaa agaaagtgtt gaaaaatgct tctcttttag
    25681 aaaagacact atcagatttt ggagtggaag caaaaattaa tcaagttaca gttggaccta
    25741 ctataacaag atatgaaata caaccaagtc caggagtcaa ggtaagtaaa attgtaaatt
    25801 taactgatga tatagcttta agtttagcag ctaaaagtat aagaattgaa gccccaattc
    25861 ctggtaaaag tgcaattgga atagaagttc caaatgaaga agctcaaatg gttggtgtga
    25921 gagaagttct agaaagtgaa gaatttaata attttaactc tcctcttgca atgggacttg
    25981 gaaaagacgt agcaggaaaa attataattg gagatatagg taagatgcca cacttactaa
    26041 tagctggttc tacaggttca ggaaagagtg tttgtgtaaa tacattaata agtagtattt
    26101 tatataaggc aaatcctgat gaagtaaaat tactattaat agacccaaaa gtagttgaac
    26161 ttgcaaatta taatggaata ccacatctat tgataccagt agttactgac cctaaaaaag
    26221 ctgcaaatgc tttaaattgg gcagttacag agatgaatag aaggtacaaa ttatttgcag
    26281 atgctcaagt aaaagatgta acaagttata atgagaaagc ggaagaaaaa cttcctaaaa
    26341 tagtaataat aatagatgag ttagcagatt taatgatggc aagtgcaaat gatgtagaag
    26401 attatatttg tagattagct caaatggcaa gagctgctgg aatgcacttg attgtagcaa
    26461 ctcaaagacc atctgttgac gttataacag gggtaataaa ggctaatata ccatctagaa
    26521 tagcatttgc agtatcatct caaactgatt caagaacaat ccttgatatg ggtggtgcag
    26581 agaagcttct aggtaaaggt gatatgttat tctatccact tggtgcagca aaaccagtta
    26641 gacttcaagg ggcattcata tcagagagtg agtcggaaaa agtaatcgat tttgtaaaaa
    26701 gtcaggttaa agatggaata aaatatgaag aagatataat tgaaactata tctaaggtta
    26761 atacttcaaa gggtagtgat gaggatgagt ttttgagtga agcgatagaa tttgtcgtgg
    26821 aaagtggtca agcatctgcc tctatgctac agagaagatt taaaatagga ttcaatagag
    26881 cagctagact tatagattct atggaagaaa gaggaataat tggagcaagt gagggaagta
    26941 aaccgagaaa ggtattaata agcaaacagg atttgcagaa tttagaaggt gaatagaatt
    27001 gtcagttata aaaatagaaa aagcacttaa gctagataaa gtaatatttg tagatgtgag
    27061 aactgaagga gaatatgaag aagaccatat attgaatgca atcaatatgc ctctttttaa
    27121 aaataatgaa cataatgaag ttggaacaat ttataagatg cagggaaaac atgaagcaat
    27181 acaaaaaggg tttgactatg tatcgtataa attaaaggat atatatttac aagcagcaga
    27241 acttgcatta aattatgata atattgtcat atattgtgca agaggcggaa tgagaagtgg
    27301 cagtatagta aatttattat catcattagg tgtaaatgta tatcaacttg aaggtggata
    27361 taaggcttat agaaattttg ttttagagta tttaaggcat gtaatggata caaaaaactt
    27421 tgtatctgtt catggattga ctggtacagg aaagactgat ttgttacatt tattagatga
    27481 aaaaggaata gatgtactgg atttagaagg catagctaaa aacagtggtt ctacctttgg
    27541 ttttataact tttgataaaa agccaccatc tcaaaagaac tttgaaacaa aactatttga
    27601 aagtatattt ttttcgaaag agaattatat atttgtcgag agtgaaagca aacgagttgg
    27661 aagtgttaca gttccaaatg aaatttttga ggcaatgaca cgagaaggac atcatatatt
    27721 attagaatgt gatattgaaa atagagttga tagactttgt agagattata tttatgataa
    27781 agatgaaggt aatatattga ttttaaaaga atgtataaac aagtttagaa aaagattggg
    27841 taataaagta gtagatgatt atattgattt attagaatca ggtgaatata aagaacttgt
    27901 aaaaagatat cttttagaat actacgaccc actttatatg cattcagtag agaaatataa
    27961 gtatagtaag attataaatt ttaatgatac acaaaaagct ttagaagatg ttatagactt
    28021 atatgagagt atattggaag gagaaagtga atgttaaaaa tagcattgga atcattagga
    28081 tgctcaaaaa atttagtaga tgcagaaata atgatgggaa ttttaaataa caaaggctat
    28141 aaattaattg gagattttga agaagctgat gtaattatag taaatacatg tgggtttata
    28201 gagtcagcta aacaagaatc tatagatacg ataataaact ttgcagagtt aaaaaaaact
    28261 ggcaatttaa agttgttgat agtaacaggg tgtctagccc aaagatattc tgaagaatta
    28321 aaaactgaaa ttcctgaaat agatgctata gtaggaacag gaagctatca aaatatagat
    28381 aaaatactta aagaattaag tgaaatgcat caaattgtaa gccttaatga tatagagttt
    28441 gtatttaatg aagatttacc aagatatata tctacaccta gctatatggc ctatttaaaa
    28501 attggagaag gatgctccaa taattgtact tattgtataa taccaaaact aagaggtaaa
    28561 tatagaagta gaaaatttga agatataatt aaagaagcta agaaattagc tgaatctgga
    28621 gtaaaagaac ttgtggttat agcacaggat acgacaaagt acggttttga tttatatgga
    28681 aaagaaagat tatcagaact tttagaagaa cttgcaaaaa tagatggatt taagtggata
    28741 agggttatgt attcatatcc agaatctata acagaggaat tgatacaagt tataaagaaa
    28801 tatgataata tatgtagtta ctttgatatg ccaatacagc atgcaagtaa caatatttta
    28861 aaattaatga atagaaaaac tactaaagaa gatatattaa ataaaatcaa tctgataaga
    28921 agtaatatac cagatgctat acttagaact acgataatag tagggtttcc tggtgaaaca
    28981 gaagatgact tcaaacaact tgtggacttt gttgaagagg ttaaatttga tagacttggt
    29041 gcatttgcat attcaagaga agaagataca ccagcagata gattgccaaa ccatatagat
    29101 gaagaagtaa aaatacaaag aagagatact ttaatgatga ttcaacaaaa aatatctgaa
    29161 gaacttaatg acaaaaagat aggaaaaact tatgaggtgt taatagaaga acagatagaa
    29221 gataatgtat atacaggaag aacacaaggt gatgcagaag aaattgacag tatagtgtat
    29281 gtaaaaagtg tagacaatct tgaagtagga gaatttgtaa gtgttcaaat aaatgatgca
    29341 atggaatacg atttaatggg agatgtttta tatgaacttg cctaacaagt taactttgtt
    29401 tagaatattt ttaataccag tatttgtttt aattatgttg ctcaatatac caaataaatt
    29461 tttaatagct tgtattattt ttataatagc ttcaattact gatgctttag atggaaaaat
    29521 agctagaaaa tacaatctag tcactgactt tggaaaattt atggacccat tagcagataa
    29581 gttattggtt atttcagcac ttacatgtat gatagaagac catcttgtaa gtagttggat
    29641 ggtaattata atagtggcta gagagcttac agttagcata ttaagagcta tagctgctgc
    29701 tgatggaaaa gtaattgctg ctggaaacag tggaaaactt aaaacgataa ctcaaatggt
    29761 atctatagtg tttttattgt taggtgctca gtttgaaaat gtattgatat taaatattgg
    29821 tgaaattctc attcttatag ctacactact tacattatat tctggatggg aatatctata
    29881 taaaaataaa gagctcttta tgtcttctaa gtaaaaaatt atgctttaat aaataaaaac
    29941 taatgattaa taaataaaaa ataacaactt aaaattttaa aaatctaaaa aagggtatac
    30001 tattatagta tacctctttt cattttaaga atattttctt ttgtgtatat aattattaat
    30061 aatggtttat aaataaaatg taatgaataa aaatataatc attagtagcg tttttaaatt
    30121 gactaggttt gatttatgtt atataattaa tatataacaa gagaacaaat gtttgtagat
    30181 aaatgaaggg atggtataga gatgagtgta gatcaagaaa aattaaaagc gttgaatgaa
    30241 gctttaggta aaattgaaaa agattttggt aaaggttcag taatgaaatt gggagaagca
    30301 acatctatgt ctatagatgt tatatcaaca ggagcgattg gtttagacat agctattggt
    30361 ataggaggtc tacctagagg gagaatagtt gaagtatatg gtccagaatc ttctggtaag
    30421 actactgttg cgcttagttg tgtagcatca gctcaaaaag atggaggaat agctgcattt
    30481 atagatgcag aacatgcact tgacccagta tatgcaaaag ctttgggtgt ggatgttgat
    30541 aacctaataa tatctcaacc agatacaggt gaacaggctt tagagatagc agaggcattg
    30601 ataagaagtg gagcgataga tataatagta atagactcag tagcagcatt agttccaaag
    30661 gctgaaatag atggagatat gggtgattcc catgtaggtt tacaagctag acttatgtca
    30721 caagcactta gaaagttaac tggttcaatt aaaaaatcaa attgtgttgc tatatttata
    30781 aaccagttaa gagagaaagt aggaataatg tttggaaacc cagaaactac tactggagga
    30841 cgtgcactaa aattctattc atcagttaga ttggatgtta gaaaaataga tacaataaaa
    30901 caaggtgata aagttatagg tagtagaact agagttaaag ttgttaaaaa caaagtagca
    30961 ccaccattta agcaagctga atttgatata atgtatggag aagggatttc aaaaattgga
    31021 gaccttttag atatagctgc tgatgtagat atagttaaaa aatcaggttc atggtatagt
    31081 tacaatgata ctaaacttgg acaaggaaga gaaaatgtta aaaaattctt ggaagataat
    31141 ttagatttaa ctactgaaat agatgagaaa gttagagcat tttacaattt aaatgaagaa
    31201 catgaagaat caggtacttc agtatcaaaa gaaattgtag aagaataagt aaaaatacaa
    31261 aaaaataact agtaattaaa gacatgccac gctccctatt agcttgacac aatgttgaaa
    31321 aaattataaa attaagtgag gataaaatat ctaaatttaa ttttaattat taggaatatt
    31381 ttttaatcat agtgatgaca ttttgggatt attaacgaag gaggtggatg tcatagatag
    31441 tgtagtaatg attgtaatag gtgcagctgt tggtattata gctggatatt ttgttagaaa
    31501 aaatatatct gaagcaaaaa ttggacaagc tgaaaacttg gccaaagaaa taatagataa
    31561 agcacaccac gactcagaaa cagtacaaaa agaaaaatta ctagaagcta aagaagagat
    31621 ccataagtgg agaacagaag ctgaaagaga aaacagagaa agaagaacag aagtacaaaa
    31681 gtatgaaaaa agagtagtac aaaaagaaga agtcttagat agaaaattac aaaatttaga
    31741 atctaaagaa gtaaacctaa gtgaaaaatt aaaggtagtg gaaaagaaag aagaagaagt
    31801 tgaagtaata aaaactcaac agttagaaaa attagaaagt atatcaggaa ttacttctga
    31861 taaggccaaa gaaatcatct taaccaatgc ggagagagat gtaagacgtg aaatgtctat
    31921 aatgataaaa gagatagaaa gtcaagctaa agaagaagct gataagaaat caagagaaat
    31981 tataggatat gcaattcaaa aatgtgcagc agatcacgta gccgaaacta ctgtaacagt
    32041 agtaagcttg cctaatgatg aaatgaaagg tagaataata ggtagggaag gtagaaatat
    32101 aaggacttta gaaaccttaa caggtataga ccttataata gatgacactc cagaagccgt
    32161 aattttatca ggatttgatc caataagaag agaaattgca agaattgctc tagaaaaatt
    32221 aatagcagat ggaagaatac atccagctag aattgaagaa atggttgaaa aggcgagaaa
    32281 agaagttgac aatattataa aagaatatgg tgaacaagct gcatttgaaa ctagtgtaca
    32341 tgggattcat ccggaattaa taagattatt aggtagactt aactatagaa ctagttatgg
    32401 acaaaatgta cttaaacatt ctatagaagt tgctcatata gctggtataa tggctgctga
    32461 aataggagca gatattagat tggctaagag ggcaggttta ttacatgata taggtaaggc
    32521 tgtagaccat gaaatggaag gtacacatgt tgaaataggt atggatttac ttagacgtta
    32581 taaagagtct aaagaagtta tacatgccat gagtactcat catggagatt acgagcctca
    32641 aacagtagag gctgtattag ttacagcagc agatgcaata tcagctgcta gacctggtgc
    32701 gagaagagaa actttagaag catatataaa gagacttgaa aaattagaag aaatagctaa
    32761 ttcatatgaa ggtgtagaaa aatcatttgc tatacaagct ggtagagaaa taagaataat
    32821 ggtaaaacca gaagctataa atgatgaaga aatacatcta ttggctagag atatgactaa
    32881 gaaaatagag gatgaacttg aatatcctgg acaaataaaa gtaagcataa taagagaaac
    32941 aagagctata gagtatgcga agtaaaagaa ataatatcta aataataaga aaatattttt
    33001 agaaatttaa atttgccaca agatatgata atatatcttg tggcttttaa attgtttaag
    33061 tttaatttta tataatgcaa aaataatcta agtgctaaaa gtgctactta caaaagatta
    33121 ataaaataaa gctttatata tgtattattt atataattat ccaagtttgt ttgatataat
    33181 gaagttgtaa aatcaatact ttactacaaa ataaatagta aatactacag taaaatataa
    33241 aaataggata taatagtatt aatataagaa gattataaat aaaacctgct aatgaaaata
    33301 gattattttt agcaggtttt taaatttttt ataataaatc ttatttttag tcaataagat
    33361 ttattttttt taaaacttta cttattattt taaaaattaa ttatgaaatt tatcgtttta
    33421 ttatttacag aaagtattct ataacaataa atatctatat ttattgcaac attattttag
    33481 cagttttgta tttatttgta tttattttga atttatttac taaatttgcc tataaaaagt
    33541 atatataaaa atatagttca aaatggtata attaagtata acagaaggag gtaatgtaag
    33601 tgagccaata cataaatata aattctcagt tagacgccct aaaattgaag gagttcgaga
    33661 aaatatttta cgaaaatatc aatgaggacg ttaaagtagt gccaaaagtt actcctttta
    33721 aaggaataaa taccgatttg ttgtatgtta aagatggaag aattttattt ataaaattta
    33781 tggatacaac agaagatata ttttttattt tagaagaaga gttacttgaa gttatgaatg
    33841 aggaatatga acttttgaaa ctaaaaatgg gacaaaagaa tagaaatata agttataact
    33901 acgtttacat tatgccatac gttgaagttg aggaaacata tgaatttgaa gaatttgtta
    33961 ataataatat aatagataaa aataagcttc aagatataat gaataagggt tcgctggagg
    34021 aatatcttaa tgatgagaat gatgaaataa acttaaattt atttttacta gatatatgtt
    34081 cagaatacta tataataaat gataaacttc atctaaatga aaaatttaaa aaaatttcat
    34141 tctacaatga tgactataag tatacagcaa ctatgatgga agacgttcaa attaaagatg
    34201 ttgtttctat taaatatggg aatacactta ttgaaggtgg ttctggtata ggcaaaacag
    34261 caattatgct ttctagggct ataaaattag caaaagtata tccacatcat aaattagtca
    34321 tatttacaca tacaaaacaa ttgtgcaatg agcttcgaga aaggatagag ttattataca
    34381 aagataataa caatttagaa gttcacacat ttagttcttt tatatttaaa ctagctaaaa
    34441 aattcaattt aattgtagat tataatatgt taaaaaatga ttacgaaaag acctttaata
    34501 atcttgtaaa acaagcacag aacattataa aaaataaaaa tatgttcaag gctattttta
    34561 ttgatgaagc agaaagcttt ttagagtatg aaatagattt tataagggag tttttatata
    34621 aaacaaaatt catatttaat gtatgttctt gtaactcctt gaatatctct aatagattga
    34681 atatatttaa aaaattatat aatggtatag aatttgatga taagattatc ttaagtaaaa
    34741 attatagaca agctaaagag attgtagatt ttacaaataa attttcaaat aattctaact
    34801 catatatcaa cgaattaaga ccaaatacag aatttagtac tttcttttat actaaagcac
    34861 ttagaggtgg aaataagtct gttgatataa taaaagtaag tgaccttgat gaccaaataa
    34921 gttctgtaat ctgggaaatt gagtatttaa taagtaaaaa aggtcttgat tattctgaag
    34981 ttgctatcgt ttatccttac aataagaaga aattaaaaag tggaaaaacc atttactttc
    35041 aatatatgtt aaaaaaagca ttggaagagg caaaaattcc ttatatatgt gcagaagata
    35101 atttgacaaa tataagtaag aaggtaggaa ctacaatagc aaatatatat gcaataaaga
    35161 atttagagta taaagcggta atagtatgtg aattagagat gttatacaat caaactataa
    35221 atgatattga acaagattat caagtaaatg actttgtagg agatttaaat aaggtttatt
    35281 tagctatgag tagagcaaca gactacctaa gtatagtaac aacttttaat gaagaagcaa
    35341 gtgatataat aagacttatt acagaatcaa aagatattta gtaaaaaaat atttgtaatt
    35401 taagaaaata aaaagagact gagatttgta aaataaactt taccaattca gtctcttatt
    35461 ttttagtcta ctttcccaat attatcaaga ggtaatagtc tcaccataac cttaccaaga
    35521 atttcatctt catcaaccat acctacatca gggaatctac tatcattact attttctcta
    35581 ttatctccca ttgcaaatag tttacctttt ggaacaacag tatctatatc tccagaagta
    35641 tagttattgt gtatatatgg ttcatttaat aattttccat ttacatacac tttagaattt
    35701 gatattttta ttctgtcacc ttcagtagct ataactcttt ttattaagtc ttttttcttt
    35761 cctgtttctc catcaactaa attggtttta aaaactacaa tatcgccttt ttcaggttta
    35821 ccaaccttgt atgatatcct atttaaaatc agataatctt tatcatctaa agtaggatac
    35881 attgattctc cacttacaat agaaggtctt ataaattgta gaattacaaa tgcaagtaca
    35941 atagccatag ctattgactt aatccaatca aatatttctt ttttaacact cataactttt
    36001 ctccttatca tttgttatta aattagaata cattataata gaaagaaata agcaagaacc
    36061 actataccca agactattct ataataacca aatactttga agtcatgttt tttgatatag
    36121 tccataaaaa atttaataac tacaattgaa acaacaaatg ctactacaga accaacacct
    36181 aaaataagcc attcaaatcc agtaaatcca aatccagctt ttagaagttt taatgcacta
    36241 gctccaagca ttgtagggat ggctaagaag aatgaaaact ctgctgctac atatctagaa
    36301 gtaccaagta atactgcacc tattatagta gaaccagacc tagatgtacc tggtataaga
    36361 gctagacact ggaataatcc tatacaaaga gctaatttat atgtaacttg agaaaaatct
    36421 ttatacttag gttttttatt tctcttttca agccctatca ttattatacc atatacaata
    36481 agagcaatag caactactgt tgaattaaag aataatctat ctatatcatc ttcaaacagt
    36541 attccaataa ctccagatgg tataactgca attataacct taagccataa acggactgtt
    36601 tcttttttct gcttaatatt ctttgcgcta tcaaaaggat ttaattttct aaaaaatata
    36661 acaagtacag ctaatattga accaaattga attacaacta aaaatgtact tataaatgta
    36721 tttgaaaaat tcaattttat aaactcatca actaatatca tatgccctgt actacttact
    36781 ggtagccatt ctgttattcc ctgaactatg cccaaaatga ctgccttaaa aatttcaagc
    36841 aaactaaatg tttccaaatc aaaatacctc caatacaaat ttatagtagc atattttatt
    36901 catagattaa taaaaaaatg ccacctttta ctaacttata ataccatagt actgtgtagt
    36961 gcacaatgga agattgatat tttcataaaa ccttcataat ataacaaaat aaacttaaaa
    37021 gttatctatt gaataagggg tatatttgag ggggaaatat atggtatagt aaaagtatag
    37081 ctattttatt ttatgaaaag gaaaggagtt attatgtata gtacaaaaat actagatgat
    37141 tatgagtatg aaacttttaa tgttttttct acaaaattaa atccaaacac gaaacacgat
    37201 tatttatcaa aggttatact gtttaaagaa tttttaaaag ggaaagaatt gatttatgct
    37261 acgaaagaag attgtaaaaa ttttgtagac tatatacaga ctaaatatgc gaaatcaact
    37321 tgtgaaaaga tatatagtta tttacatagt ttttataact tcttaaaaaa agaaggatac
    37381 atagatataa atccatttag atatgtagaa aaacccacag taacaagaat aaaaacaaaa
    37441 gatgatgttc taagtataca agaaataaat aaacttatag gtatcctacc aaaattaaat
    37501 ataagagata gagtaataat agtctgtcta gttactactg ggtgtttatt aaatgaatta
    37561 gttagcttaa agtggaaaga ccttatggta gatgaaaacg ataactcata tgtaaggtta
    37621 ggtaagggaa gaaaagaaag agtagttaaa ttacatccat acttttttaa acttttagaa
    37681 gattacagga attattctgg gcttccagag gtaataatac ctagtgatga ttttattttt
    37741 acaactcaaa agagtaattc tataacagat agaaatgtca gacttatagt caaaaaagca
    37801 ttagatttag ctggactttc tcaatattca gcaagagatt ttagacattc atttgcagca
    37861 ataagtttaa ggcttggggc agatgaaagt gatgtaaaaa atcagcttgg atggagtgat
    37921 aaatactatg caattagata taagtatgta ttaaattttg ttgatagtga aatagtggat
    37981 tacttaattg aaaaagataa tttggatata aataaaaaat agtaataaat aaaaaatact
    38041 atatataaat gtgaacaaaa aataaaaaag tcttgttata gttcgtaaaa ttatatataa
    38101 ttatttatgt actaatgtgt acacagtaat cacacgacaa aagatttaag gaaggtgcta
    38161 atataatgat agataataaa tatactactt actcaaaccc acttacagac agatattgta
    38221 gcaaggacat gagttatata ttttctccac aatttaaatt ctctacatgg agaaggttat
    38281 gggttgcact tgcagaaggt gaacatgagt taggaatcaa tataactgaa gaacaattag
    38341 atgagctaag agctaatata gataatataa attttgatga agctagaaaa atagaaaaag
    38401 aagtaagaca tgatgtaatg tctcacgtaa aagcttatgg tttacaatgt gaaaaagcca
    38461 aaggaataat acatttagga gcaacatctg catatgttgg agataataca gatgttatac
    38521 aaatgaatga agctttaaaa cttctaagag taaagcttgt aaatttaata aacaatttaa
    38581 aagaatttgc acttaagtac aaagatatgc cagctcttgg atttacacac ttccaagctg
    38641 ctcaacttac aacagtagga aaaagagctt gtttatgggc tcaagattta attcttgatt
    38701 tggaagattt aaactataga atagacaaca tgaagttaag aggagttaaa ggtactactg
    38761 gtactcaagc aagtttttta agcttatttg aaggagacca cgaaaaagta aaagagttag
    38821 ataagaaaat ttgtaaaaag atgggatacc attcttccta tgcagtaagt ggacagacat
    38881 atactagaaa gttagattat caagtaataa gcatactatc agggatagct caaagtatgc
    38941 ataagatgac taatgatata agacttttac aaagtttaaa agaattagaa gagccatttg
    39001 aaaaaaatca aataggttca tcagcaatgg cttataagag gaatccaatg agaagtgaga
    39061 gaatagcatc tttatctaag tatataatct ctgaatctat aagccctgca atggtacaag
    39121 ccactcaatg gttagagaga acattagatg actcagccaa taagagattg gcaatacctc
    39181 aagcatttat ggcagcagat gctatacttg aaatagggat aaatgtaact gatggtttag
    39241 tagtatatga aaatatgata aatagacgtg taaatgaaga acttcctttt atggctacag
    39301 aaacaatact tatggaagct gtaaaaagag gtggagatag acaggaatta catgaaataa
    39361 taagagaata ttctatgaaa gctgcctata gagtaaagca tgaaggcaag gataataact
    39421 taattgaact tataatgaat gatgattcat ttaaaatgag caaggaagaa atactatcta
    39481 taatggaccc aaaaaacttt ataggtagag ctccagaaca agttgtagaa tttgtaaatg
    39541 aagttgtaga acctgctata aaagattata aggaagactt aggaaaagta gatgtagacc
    39601 taagagtata gaattgtaca gataaaatat aattaaaaac ggctatctta tttataaata
    39661 agatagccat tttaatgggc tagcgtcttc tctccaccgc tgtgaagagt tcttctttac
    39721 ttactatacc atgaatttaa taaaatagct atataaataa tatttaatag gaataatata
    39781 aataaaaata aaaaaatgat aagattacta attaaattta aacattcagc aaaaactatt
    39841 gtacttgcaa tatttttaat gtaaactgaa ataaagttat ttagataatt taataaattt
    39901 taaaacaacc gaggtgatta tatgaactat atagtaaaag ataccataag ttttttagta
    39961 aaaacatttc ctaagattta ttctagcctg tacttagaag acctaaaaaa atttgcacca
    40021 gattataatg taaataaaac acaattaaga gcattagttt tcataaaaaa ttatggagta
    40081 ataagtatga ctgatttatg ctctaagtta aatatagaaa aaggcagttt aactagtatg
    40141 gttgatgatt taactgataa gaagtatgta acaaggaaaa gagatttagt tgatagaaga
    40201 aaatatctaa ttgacattac tgaagaggga gataagatag caactgattt tatggataaa
    40261 ttaagtgatg gtttaggaga aaaactttct aaattaactg aagaagacag aaaaaaatat
    40321 ttagaagcaa taaatactct tcaatatata ttaaacaaag aagaatttag atagaaaaaa
    40381 tataaaaatt tttgtattta atggtactaa gattaattct ttgttattca tttaactata
    40441 taattataag tctaaataca atctaaaaag tacatcttaa atttttttga tgtacttttt
    40501 tataatttct ctaactaagg caagacaagt tttagatgct ttaattaaag tgaataaaga
    40561 ttactggcca acactatata aagaaaatga aaaatagtca ggtctaagtc ttaattaata
    40621 tattaattaa gaaatgtccc cttttcaaat aatatctgaa aaggggacat tttatatcat
    40681 taaatttata taaattaagt ttaaaaaatt atttttgtaa agctacatat tgctctaaac
    40741 cttcttttaa taatgtagca gctctatgaa ggtctttttc atttaagatg taagctaatc
    40801 ttatttcatc acgtcctaaa cctggagtag catagaatcc ttcagcaggg caaaccataa
    40861 ctgtttcatt atctttgtta aattctttta acatccaaat tgtgaaatct tctgcatttt
    40921 caactggtaa tttagcaact atatagaaag caccagttgg ttttttacat ataacacctt
    40981 caaccttcat taattcattg tataatacat ctcttctttt tttgtactct tcattaactt
    41041 ctttgaagta agaaacagga gttttgtata actcaacagc tcctatttgc tctaatgtag
    41101 gaacacaaag tcttccttga cataatttaa gtatttgagc gataagacct ttatttttgc
    41161 aagcgataga accaattcta gcaccacaag cactgtatct cttagaaaca ctgtctatta
    41221 ttataactct atcctgtaca ccctctaagt taccacagct tgtatactca agcccatcat
    41281 aaacaaattc tctataaact tcgtctgcta ttatccataa atctttttct ttagctattt
    41341 cagctaggat attaagttct tcttttgtat aaattgcacc agttggattt cctgggttag
    41401 aaagaattat agccttagtt ttatcatcta ctttagacaa tatttcttct ttagatggaa
    41461 ggtggaaacc gttttctgcc tttgttgtaa cagcattaac ttctacgttt acagattgac
    41521 caaatccatt gtagtttgta tagaatggtt ctggaactaa tagattatct cctgggtcac
    41581 aaactgccat catagtgaaa agtaaagctt cactaccacc attagttact aataattcat
    41641 ctttttcaaa attcatatcg taagttttat agtaattttg aagtgcttct aataattctg
    41701 gaataccttc tgatgtagca tattctaaga cttcgctatc aaagttttta acagcatcaa
    41761 aaaatccttt aggagttttt atgtctggtt gtcctatgtt taagtgatat actttgattc
    41821 ctttatcttt tgctgcttgt gcaaatggaa caagttttct gattggagag gcttgcattg
    41881 cactaactct gtttgaataa ttcattttaa taccccctat ttaatttaaa tacgtatatt
    41941 gtattatgta aattgtatgt ttgaatacaa gacatcttta caagataata ataacatact
    42001 tatgggtaaa aatcatcaaa aaaaattaat atagctttaa aataaacttt taacaaatta
    42061 tagtaaaata cccatgttta tgccactaaa ttatgtattc ataaattaat ttatagtaag
    42121 ataatattct gatatactga tagtgatttt ttagttataa tctttcagct atagacaaaa
    42181 tatataataa taaatatgca aaattataaa aaatattata aatttattta acagatacga
    42241 taaatatcat ataattatat taaaggctat taactaagag gtgttaatta tgaaagaatt
    42301 aagaatagat ccaattacca atgatgttgt tatatttgct acagataggt taaaaagacc
    42361 tttagataca gcagatatcc caaatgaaga tgaagaaact aatgaatatg atgaagaatg
    42421 cccattttgc aaaggaaatg aagctcatgc aactgatgca ttatttgaaa tagatagtga
    42481 agaaggatgg cttgtaaaat ctgtctacaa taaatttcct ataattgatg atatggcaag
    42541 agatgtatat ggtgttcatg aagtaatgat agagagcgat aaacataatc gtagttttta
    42601 taacatgagt caaaaagaat ttgaagatgt tttttttatg tatagaaata gatttagaga
    42661 tttgtcgaaa gatgataaag tagagtatgt tagtatcttc aaaaacttct tgagaaaggc
    42721 aggagcatct ttgatgcatc cacatgctca aatattgtct atgtctttta ttccacctga
    42781 aattacgaat gaactgttgg tttcaaagga gtattatgac agcaataaaa gctctttgta
    42841 tgatgattta atagaaaatg aaataagttt agatagaaga gttgtttata atggagaagc
    42901 ttttttggta cttataccat atgcaaccaa gtatagtgga gaagtaagaa taatatttaa
    42961 agataaaata gagtttggtg agttaaatga taataatata caggagcttt ctacaatatt
    43021 tgaaaagttg tttaagaagt tatacaatat caatggatat atgccattta atttatgtat
    43081 tcacactcat ccaacaaaga ttgaaacaaa atcgtatttt aatgttcata tgcacataat
    43141 cccaagaaaa tataattttg gaggatttga acttggaaca aatatgtatg tttcttcaat
    43201 gagccctgaa gatttaacaa aaaagttaaa aattgattaa aacatatatt tttaggtatt
    43261 aagtaaatag taattttaga tgaaattata gtatagcatt gttaaaataa aagtgaatta
    43321 agaatttaca ataaaattgt tgaaaagccc ccatctttag ctatggggag tgtgtcaatg
    43381 tttagatgag gagtataagt atgaaattta tatcatggaa tgttaatgga ataagagctt
    43441 gtgttgggaa aggattttta gactttttca aagaagtaga tgcagatata ttttgtttac
    43501 aagaaactaa attgcaagaa gggcaaatag agttagattt accaggatat tttcaatatt
    43561 ggaattatgc tgagagaaag ggttattcag gtactgctat atttacaaaa aaagagcctt
    43621 taaaagtaat gtatggaata aatatagaag aacatgacaa agagggtaga gtgataactc
    43681 tagagtttga agatttttac tttgttacag tatatacgcc aaattctcaa tctgaattaa
    43741 agagactaga atatagaact agatgggaag acgactttat agattattta accaaactag
    43801 ataatcataa gcctgtaatt gtgtgtggag atatgaacgt tgcacataaa gaaatagatt
    43861 taaaaaatcc taaaaataat atgaaaaatg caggttttac taaagaagaa agagagaagt
    43921 tttctaaatt attagacagt gggtttatag acacatatag atattttaat cctgataaag
    43981 aaggtgttta tagttggtgg tcatatagat ttaatgcaag aaaaaataat gcagggtgga
    44041 gaatagatta tttttgtgca tccaaaaaat tagaagatag attagtaagt gcggatatac
    44101 acactgaaat attaggttca gaccattgtc cagttgaatt agagatgaaa taaaaattaa
    44161 ttatgataaa aattgggctg tagatataaa tttaaagtta actagttttt taatctacat
    44221 gcctattttt tatctaaata aactctattt gttttttctt tgcttaacat tttctaatgt
    44281 aaattgattt gttttcccca tattataagc taagttaatg atttttttct cgtctttagt
    44341 taattcacga tttaaaattt tcctaaattc atcaaataac ttatcataat caactctttt
    44401 tttattagaa tatcttatag ttttaggttt tatactcgta taaagatata tatctgggac
    44461 tatacttgga ttgtatatct taataaaaac tttagcagta taatatgcat catttaaagc
    44521 attgtgataa gacatttttt catcaagttc taatatagaa atagcatttt gtagaccaat
    44581 gctttttcct gctggattat tgaaatattt agatgcatgt tgttgtatat taatataaga
    44641 tttaggtaag gaatttgatg gtagcttgtg atagttgata ttcctgtata attcctttaa
    44701 atctccagct ccccaaacac ataatatagg gtcttgtgat gatataaatt ttataaaatt
    44761 gttgtagacc tcagggaaag taggcgaatc attaaaatca gaatttttaa tattagtcat
    44821 acgactaata aagggatgta tgtctttata aattgtaggt tttacatagc tattaaacgt
    44881 atctattata ttgaatttag aatccaattt aattgctcct atttgtataa tttcaaaagg
    44941 acacttttca ttggatacag ttttattgag ttttttatca aatccttggt taaattccaa
    45001 atcgaaaatt atgtattcca taaagtttat ctcctaaatt tttttattat ttcttttact
    45061 atagattata ttataaataa aattaaattt tcaaataaaa atacttttat tttagtatac
    45121 cccatatttg taaaaatgtt aaactattgt atgtataata ttttttccaa taaaaaatat
    45181 tgcgaacttt ttatacttga tatataataa tataaataaa aacacgaata aaacacgaat
    45241 aatttgcaag aaaaattcat aaatgtaagg aaaatgaaat ttatcttgta tttaacaaaa
    45301 taaaatatac ataaaaatta tgggagagtg gaaaaatgga tagtctatta tacgtaatag
    45361 agaaagataa acacactaat gaagaattaa gagaaatcct aaaaagcaat aaaaatataa
    45421 gatttgtttc cttaatgggg gttgatttag gaggaaatgc aacagatgaa aagattcctg
    45481 tagaattatt tttggaggat atagataaat ttttggaatc agctatacag actgatggtt
    45541 caagtgttga gctttataat atagctacat taaataatgc gaaagtagat ttaatgccag
    45601 ataaaagttg tcattggtat gtagattaca atatggaata tatagacgaa gaagtaggtc
    45661 tacctgttgg aacattaaag atacctgcat ttttaataca tgataataaa aaagtatgtt
    45721 ctagaggagt acttcaaaaa gcagataagt actttaaaaa gtcaatgtat gaaatattta
    45781 gagaatatcc acatgtaata aataacatag gaatagattc agtagatgat atagaggaaa
    45841 taatgttaac agcagctaca gaacttgagt tctgggttaa tactcctgag gataaagctg
    45901 acttagagaa attatatgta tcacaaagcc taaaagagca atactggaaa agaactcatg
    45961 gtattataag aacttgttta gagaaaagtt taattatact tcaaaagcta ggtgtaaacc
    46021 ctgaaatggc tcacaaagag gtcggaggaa tacaaagttc tattagtata gatggaagaa
    46081 caaaccatgc tatggagcaa ttagaggttt cttggaagtt ttctacacca ttacaagcag
    46141 cagacaatga attattagta agagatgtta tagaggatgt atttacatca catggactag
    46201 aagttacatt taaagcaaaa ccaattcatg gagtagcagg aagtggtgga catacacatg
    46261 taggagtaag tgcgaagtta aaggatggaa gtataaaaaa tctatttgct ccaaaagatt
    46321 taaaagaaga ttatctaagt gaactaggat atggggctct tatgggactt ctttacaatt
    46381 atgaagtatt aaacccaatt gtaacagctt ctaatgatgg ctttaataga ttagttcctg
    46441 gatttgaagc tcctgtatgt atagttacat ctttagggca tagttatgag attccatcaa
    46501 gaaataggtc agtgcttgtt ggattaataa gagatatgaa aaatccaaag actgtaagat
    46561 ttgaattaag gtcaccaagc cctctatcta acacgtattt agtaatagca ggatgttatc
    46621 aaacaatgtt ggatggtata aaagcagcag ctaagagtgg tcttagtaca aaagaacttg
    46681 aaaaagagtt atctaaaaat gtaggtgaag aaagtttcta tttagaaaaa gatagagcat
    46741 atagagatga aaatgatgta tttgaacatt atagtttgga agaaagaaat gcaagatttg
    46801 gaatgccacc agctacagtt tatgaaaata tgaaaaactt agaaatatat gcttcaaaat
    46861 taaaatcttt aaaacaaggt gatgtattta ctgatagtat aatagaatca tttaagattg
    46921 gagctataga taagtggcaa aagaaattaa aaactagaat aatagaggct gggattcaaa
    46981 aaataagaag tattgtcaag atacacacaa aagaaaatat ggatgcgctt gatgaggtag
    47041 tttggaactc aatatcggat ttaaagttca atattatgaa ggatacttta actagagaat
    47101 cactattcac tagagtgaga gaagctatag aaaataagga ttaccagact gcttcagatt
    47161 tacaaataga attaaagaga agtatggaag aaatacaaca actgtatatg cagtacaaga
    47221 aaaatatata ctaatataac aatttgattt tgatatgata aaggcaatca agtattatta
    47281 aacactatga gtaaattctc aagtgtaaga gcatacttga ttgcctttaa ttttatgttt
    47341 gaaatttttt aatagtacaa tttaactgta atgattatct attaattctg atatataatc
    47401 agcaattttc tctggatgaa tgactgtttt aaattctttt aaattttttt tcataaagtt
    47461 tattatagaa tcaaattcat ttgatactaa tttataaaat atgtttttaa ggtctaggtc
    47521 atcactataa atcatgccaa gacccttatc tattataaat ttagcgtttt caatttcttg
    47581 tccaactttt ggcattttta cgagtactgg agtttgtgat tgaatagctt caaatatagt
    47641 tgctcctcca ggcttagtta gcattaggtc acattctctt attagattat acatgtcgtt
    47701 tacaaatcca agtactttaa tattttttag aggtttttta tgagttagat tgtcatataa
    47761 ttttttgttt ttaccagtaa ctattgtaat ttctatagaa ttactatgtt cttcaataaa
    47821 ttcatctatc caatgcataa aatcctcatc tatatcaaat agacctcttc ctccacctag
    47881 aagtaatagt ctatatttat cacaacatag ttctttactt tcaatttgaa atctcttatc
    47941 aacaggaact ccagtaacct ttatggagtc tggatttatt cctttctgaa aaaatctatt
    48001 ttttatttca ggagaaggaa caaaatacaa atctgtattt tcaaaaaccc attccatact
    48061 atctacaaca tctgttataa ctgtaagtgt aggtatattt atatcaggat tttttatctt
    48121 aaagttattt acacaagcag cagctagtgg aaatgtagag ataatcaaat ctggatttat
    48181 atcagcaata tactcagaaa gtttaggtgt atataattta tgagataaat catgtcttga
    48241 atcaaacgat ttcttaaagt aataatagta attatataat ccaggagtat attttgtatt
    48301 gttttcataa agttttacca taggcttatt catcatggga atacttgcat ttataaagtt
    48361 ttgtataaca acattatagt tactatattt ttcaataata cattctttga ctgcttttgc
    48421 agcacttata tgtccagcac caaattgagc agttaggatt aatattgttt tatcatcttt
    48481 cattttagcc aatttatcac cactttcata aaatatatct gattagagta ttatacattt
    48541 atagaaggat ttaatcaaca agaatattta aaaataacta ttgtgcagaa catagtactg
    48601 tgttattatg aggatataag aagttttaac atagtacctt gtaaaacaca atactgtgta
    48661 tttaaagaaa ggatggagta tatgaacaca caatttagaa agggtgtttt agaaatttgt
    48721 gtacttgctc tcatatctaa gaaagatatg tatggatatg agatagtaca taacatctct
    48781 aaagtaatag atgtaaatga aggaacaata tatcctattc taagaagact tacaaaagat
    48841 ttgtatttcg aaacatatat actagaatct aatgaaggtc ctgctagaaa atactataga
    48901 ataacttcac taggaaaaga gaatttatcc aatctgatgg aagagtggag agaatttgta
    48961 aaggctgttg agattttaat aagtgaagat gagggaggta atgaacttga ataaaactga
    49021 gtttcttgaa attttaaagg attatctaaa aaaagatttt tctgagagcg aagttaatga
    49081 tatattgaga gattatgaag agtatttcgt agatggtctt atagagggaa agagtgatat
    49141 ggagataata gcatcacttg gctcaccaaa atctatagca aaagaactta tcttacaaac
    49201 taaagaaaaa aatattgaag aggaaaaaat aataaataca gatgttttga atgataagtt
    49261 tagtaaattt aaatcagata tgaaaaaagg ttactctatc ttaaaagatg aagcaaaaga
    49321 aaagtatagt aaatcaaaag aaaatataga tggaaaaata atgaatacag acatattaaa
    49381 tggtaaattt agtagattta aatcaaatgt aaaaaaggat tactctatct tgaaagatga
    49441 agctaaggaa aagtacaata aatcaaaaga aaatataaat gataaactta caccaagtat
    49501 agaagaaggt gtaggaggat tatccagaca agttataaag gggttattag tagtgttatc
    49561 tttatttcta attgttccag catttgcgtt tgtatgtgct attgtatctg ctactattgc
    49621 attagtatgc tcattaattg cttttgttat attaattcca tttgtgatta aatttatagc
    49681 aatggttcca gatgttatga tgttttgtat tttcgcaacc atagcatttg tagggcttga
    49741 gatacttgca tggcaaattt tattatttgc cataaaacta ggtaaacaat tactaaataa
    49801 ttatatacat tggataaaga gaaaaaatat ttatataaag gcaaatgaaa agatggaaaa
    49861 aagaaaaaaa gctactttaa atgatgaaga tttgaataaa gacattaatg aagactcata
    49921 taataatgat tactacaata gagaagaaga aagcataaaa gaaactgatg aatataatga
    49981 tgatagtata aattttgagg cgatatataa ggaccttgaa gatatagaaa ataagaaagg
    50041 agaagataaa tatgaataaa aaacttgcta tatttgctgc ggtattattg gtaataggta
    50101 taatagggac aacatggtca gggattttag ttatgccaag cttaataaac tttggtttag
    50161 aaaaggaagc tgaattaaac aaagaaaaca aactttatca agaaaaagta aatattgaca
    50221 agttagatat agctgttgac aatataaatg ttatgataag aaaaagttca aatgaagatg
    50281 tgcgtgtgac aacaagaggg aataatgaat tttacaaata cagtgtaacc ctacaagata
    50341 agactttagt tgtaaaaggc gaaagaaaat ctgaaaataa aattaaaaag attagaagtt
    50401 tcgaccactt attaaataca tctataaata gtatgttttc acgtgattat agagaaatta
    50461 gaatatatgt accaaataat gtagatataa atgcatcaag tataagttcg tacttattta
    50521 tatctgatga tgtagattca aataatataa catataaaac ttcttctgga ggttttagca
    50581 gagctataac agaaaataaa gtaaatagat tagaaaactt aaacttaata tctaatagca
    50641 atcttcatct atcaacaaag tcaattttag gcgttaaaaa tgtaaacata gaatcagagt
    50701 cattggatat atcctcagag aatggagatg tatttatcaa taatatagaa gagtatatac
    50761 ctgaaaatgt aaatataaaa gagaaaatag gtagaaattc aaattatgaa agtgaatttt
    50821 acttgtactc tgatatgcca attgctaagt tcctggacat agaagttcca aattctaagg
    50881 taagacttga tataccagta aataagtata aatttaattg tgatataaag tcaaaagaag
    50941 caattgaaga atttaataat gatgaagaat atgacaatga ttcatatgat tatgaacata
    51001 gtgaagaaca tagcaacaag tatagaaata cgagggaaat aaaagggctt ttgaataaaa
    51061 atctgtcgaa tttagagaaa gaatatacta taaaaataaa ttcaaatagc ttagaattgt
    51121 aaataattta ctataataat ttataaattg atttaaaagt ataaaaatat aatctatact
    51181 atggtataat aagtatcgaa agagaattag gagagggata cttatgaata aaatagcagt
    51241 aagtttttta ataattgcta ctactttatt gagtacggca tgtatggatt atagcatcag
    51301 tgcagttgag ctagttgatt ctaaagaatc agcagttgta aagaaggatg aagatgcaaa
    51361 agaagaaaca actagtaaaa tgattaattc taaaaaaact actaaaatac ctatagagat
    51421 aatttcaaag gatgagaaaa tagtaaagta cttacagatt gatgaagaaa gttcacttaa
    51481 ggataaactg cgattaatct tagatacatt atcaaatgag tattttaatg gtttagacat
    51541 ggaagtagaa gttaaggaaa aagataatct tgttaaaata aacttgatag aaccagataa
    51601 aaaaagtaga gtttcttgga aagatgatta tttgaatgaa caaaatataa tatatactat
    51661 aaataatatt attaaaaatg tcatccaaga agaagataat agcatttgga ttgaagaagt
    51721 agagatatac tacaatggaa aattaataga attaagataa aaaaagatgt gtttttaaca
    51781 catctttttt tgttttttaa ttcttataaa atccttatat ttatgattta gaatgattct
    51841 tgtaaataag tttgacaaaa gaaaggatga aaattatgag taattatatt ttgcaggtaa
    51901 aaggagtttc taaaaaattt aaggagcaga tggcagttga taatatttca ctagcaatta
    51961 aatataattc tatatatgga ttattaggac caaatggagc tgggaaatct actttattaa
    52021 aaatgataac tgggatttta aatccaactt caggaaaaat aatgtttgag ggacatagat
    52081 ggactagaaa ggatttatca aatattggtt ctcttattga gtctcctgct atatatgaga
    52141 atttaacagc acgagaaaat ttaaaagtcc atactacttt acttggtctt cctgactctc
    52201 gcattgaaga agttttagag actgtagatt taagagatac ctttaaaaag cgttcaggtc
    52261 aattctctct aggcatgaag caacgccttg gtattgctat tgcattatta aatcacccaa
    52321 aacttttaat cttagatgag cctacaaatg gtcttgaccc tattggtatt gaagaactta
    52381 gagaattgat tcgttctttt ccaaaacaag gaattacagt tattttatca agccatatct
    52441 tgtctgaagt tgaacaagtt gtagatgaaa taggaataat ttctaatgga gtaatgggtt
    52501 atcaaggaga agtatcaaaa gaacaaaact tagaaaaact ttttatgaaa gttgtagctg
    52561 aaaatagaaa gagagggcag taatatggaa agatttatta gagtggaatt tcaaaagatg
    52621 aaaggaactt ttggaatgaa gttgatatgg atagttccag tgttttgtat acttttgtgt
    52681 ggactaggtg gagggcaaaa tgctgctttc aactggtggt atacgacatt tcttccagga
    52741 gcattaacat taatatcttc tttaatagta ttaaaagatg aaaaaagtaa atatcgtggt
    52801 attttaccat tgccaattga aatgaaagac gtttggactg gaaaaatgat ttactgtatt
    52861 atttgttgtt ttatagcatc aattatttct gcaataggtg tagtttttgt tgggataatc
    52921 tataaagaaa ctatttcaat aggtcaaaat atcattgcaa ctatattaat tattttacta
    52981 tttatgtggc agattcctct ttgtatgttt ttagcttcaa aatttggtat ttttgttaca
    53041 gttctaataa atatgttctt tactattgtt ggagttgctg ttttctcaac tacagaaatg
    53101 tggtatatgt ttccatattc gattccttca agattaatgg ctgttgtatt gcatattctg
    53161 ccaaatggtc ttcctgtacc agagggaagt gaatttttaa ataatgctgt tattttgcca
    53221 ggagtattaa tatctattgt tttatttgta ttatttgctt tagctacaag ggtttggttc
    53281 aataatagag aggtgaagta atatgagaca gttaataaga atattttgtt ctgatttaat
    53341 aaaattaaag agaaatttta taatactaat gcacatttgc attgctttaa tggggatggg
    53401 attgttttta tggtattata aggtttcagg agctgataat atactaaaga tagtagcata
    53461 tttacaagtt atagcaatag cttttccttt attgtcaggt gttgtgtgtt caatgtttgt
    53521 tgaacaagaa tattatgcag ggaattataa acatatgtta acaacatcta atccaaaata
    53581 tcttactctt ataagtaaat atataatctt agtatgtctt ggttttgtag caacattagt
    53641 gtctgtatta ggttttaaat ttggtatatc taaggcttac tttgcatcaa gcttttatat
    53701 gatttcaatt ctaattttaa ttgggtgtaa tttatttgaa tacatattac atttattctt
    53761 aagtttaagg ttcggaaaag gaacatcaat tggagtaggt atagttgaaa tgttactttc
    53821 agcattatta ttaactggat tgggttctgg tatttggcag tattttcctt gtgcatgggg
    53881 tgttagattt ataactattt ggtcgtcttt ttcgagttct aaaacggttg aatatataaa
    53941 ggttgaatca ataaaagcat atcaatcaac aggtttaatg tgtggttttg taacaatttt
    54001 agcatttgta attttatgta tttggttttc taaatgggaa ggtaaaaaat cagaagaata
    54061 gaataaaaat tggctgttta tttacattat atttatatta ttatgttaaa atataactta
    54121 gcaataaaaa gatataaaat aatcaaataa aaagctggtt aggtattaat tatgaattaa
    54181 ttaaactatt ggaggacagg gtacaaatgc ttggaggtaa aaaatctaac aacaaaaaag
    54241 ttgaaaagtt aagaactatt tttataaaat atttatcttt attctttatt atgacaattt
    54301 caattatact tattttgatg ttattgtttt cttggttatt atcatcaggt gtaatattac
    54361 cagctaatta tgcagaaaaa caatttaata aatataaaga aaagattatt tcaagtgaaa
    54421 aagtaactga agatataatt ccaaatatat acgagtatgg ggtttatact ttagatggga
    54481 atttaatttc agggacattt aataaaaaag aatcaaaaga agtatggaat ttaatgagag
    54541 atattgaaga aaggcatgca tattcagaaa gttatataaa gttttttaag aaagataaag
    54601 tttttataat aaaatacaaa atagtatcag agtatagttc tccaatttta agagcatatt
    54661 taccaaaacc agagacattg ggtatgatta tttttagtat aatatttttt attgaaattg
    54721 ttatattatc aaaagtattt ggcaagaaat ttaatattga aatggagctt ttaaaaaata
    54781 ctacagaaaa aatagaacaa caggatttag attttgttgt agaatctagt aaaatttatg
    54841 aaattaataa tgtccttttt tctatggata aaatgaagtt ggcgttaaaa gagtctttag
    54901 aaaaacaatg gatgctagaa gaaaatagaa aggaacagat atctgcactg gcacatgata
    54961 taaaaacacc actaacaatt atacatggaa atactgactt attaattgaa ataaatgaaa
    55021 atccggagtt attagaatac atggaatata tctcaaaggg tgtcactcaa atagaaaaat
    55081 atattaatac tttaatagat atatcaaaaa cagagaatgg ctatatatta aataaagaag
    55141 caatcagtat gagtgagttt ataaaagatg tcttagtgca aatagaagca ttagctagta
    55201 ctaaaaactt agatgtggag ttttataaac aagataattt gcctaaaaat ataactatag
    55261 atagagaact gttattcaga gctattatga atataatttc aaatgctata gattattcac
    55321 caagccagag taaactatac ataagtgtat cagtatgtaa taaatactta aaatttatag
    55381 ttacagattg tggaagtggt ttttctaaag cagatttgtc aaaagctaca gaacagtttt
    55441 atacaggaga tttgagtaga aattctaaat ctcattatgg aatgggactc tatattgtaa
    55501 ataatattgt acaaaaacat aatgggattt tatatattga aaattctgtg aagactggtg
    55561 gtgctatggt aacaattgaa ataccaatag tttagtaaat aatatccatt ttgtaaatac
    55621 ctaaatttta tgatttatag gtatttataa aatggatagt ttttttgact ttatatatta
    55681 gttaaatctg ataaaaagtt ttcaaacata actccatcat ttctatcagt atcaaattga
    55741 gatgtgtaat ttatagtttt atatataaaa tctgttgcag tattaaccgc tactcccaaa
    55801 tcatgtttat ttactaacat accacaaagt atagatgtga atatatctcc agttccactg
    55861 taagaacaat tattgtattt gactgatgta aagaatacat ggtcattatc tctatcgtaa
    55921 gccaaattta atatattatc atcttctaat ataccagtaa taacgacttt gctaggtccc
    55981 aaatcagata cagattttgc aatatatata agctcatctc tattataatc gcttttggta
    56041 taatcatttc cagtcaagaa acaagcttct gttaaattag gagtagttaa atctgaatgt
    56101 ttaactaatt ctttaatttc ctgtctcatt tcttctgtga atattggata cataactcca
    56161 ttatcaccca tcacagggtc aactacgata aaagcattgg gataatcgtt tataaaatta
    56221 gccactatct caatttgatg ctttgaaccc aaaaaaccac tatatatact atcaaaattg
    56281 acttttaaat ttttccaaac atttgaatat tttaccattt catcagtaaa atctaagaaa
    56341 gtaaattcag gataaccagt ttgacttgaa agtatggccg ttggaaatgg acaacattga
    56401 acctttaatg ctgaaagtat aggtatagca accgataatg agcattttcc tattccagat
    56461 aagtcattaa ttgctgcgac ttttttttgc ataaaaaacc ctccattagt atgtattaat
    56521 tataatgata ccaaaatatt tatatacata tatattacta taaaaaaaag aaaaaagtag
    56581 attataaaat aaaaaattgt aaaaaaaaca gtgtattgat acaattaatt tttaatattg
    56641 gacataataa aatagagaat tattaaatat gaaaattact atatgtgaca gaatattctt
    56701 tgtaatttga tttgtaaggt gtactatttg ggaggtgtag ctttgaaaat actgaaaaat
    56761 aagaataagt acatcaaagg tataatggca tttgtatttt tgtctttagc tactacagca
    56821 ggtgtatttt taatcaatga tttaagtatg aaaaatatgg aagaaaaagt catggaatct
    56881 gcaaatgttg aaggtgatga tgtaaaagac caatataaac tattgcttga aaacttattt
    56941 gattacagaa ataaggcaat attagagaaa aatgaaaata ttttaaaagg tctttatgag
    57001 acggataaaa aatttggtct gtgggcttat gaaaatgaag taaaaaagat gaagtattta
    57061 gaaaactggt ctagtaagca aggtgtaaaa tttaaagaca taaagacaag ggttaagatt
    57121 aaaaaaataa aagaaaaaga aaaagacctc tatggtataa tctgttcagt atcgactgaa
    57181 tataagtatt catatgaaaa tcaaaaggac aaagaaaatg cctttagaat aggtacatat
    57241 cattatctaa atgtaaaaat tatagataat caatatgtca taactaaaga gtggtacaca
    57301 gacccttttg cagactcttt aaatttagaa aatataaaat ctgaggatat aagaaactat
    57361 attgggcaac aagatggtgt agagttacag cttacagatg aacaaaaaaa ggctatagat
    57421 tatgcacata aatactgtgg agccgcagct gatgaagaac atggtatgaa atttaatcca
    57481 aactataggg attataatcc agaaggtgga gattgtgcaa actttgcatc acagataatg
    57541 tttgaaagtg gaaggtttaa aaagaactca atttggaatt atagcgagag agcaggtaca
    57601 aaagcatggg taaatgcaca agcttttaaa aattatgcac tgtatagtgg aagaggttca
    57661 ttaattgcta aaggttccta tgaagaagta tacaaagaag cttataattt acgtccaggg
    57721 gattttgttg gttatgagaa gaaaggcaga ataacacatg tttcgacagt gacaggatta
    57781 gactcaagag ggtatccttt ggtaacctgt cataatactg atagaatgtt ggtgccatgg
    57841 gatttaggtt ggagtgataa gtccataaga ttccatataa taaaaataaa ttattaaaaa
    57901 attataaaga aaaataaagt gtaaaagata ataatcattt aaaattataa agtaaaaaaa
    57961 ttgattatta atgtataaaa ataataataa ttgacaaaca tagctatata tgatagagta
    58021 gtaataaggt tacagaaaag agtagctaaa tatttgtgtt tttttaggag gatttattaa
    58081 tgaaaactgg tgtagttaaa tggtttaaca acgaaaaagg atttggattc atatctgtag
    58141 aaggtgaagg agatgttttc gtacatttct cagctataac tggagatgga tacaaaacat
    58201 tagaagaagg acaaagcgtt gagttcgaag tagtagatgg agctaaaggt cctcaagctg
    58261 ctaacgtagt tagattataa ttaaaaattc atatatatta gtgttctagt aatatgagag
    58321 ataagccgct aatcatttag cggttttttc agtttttgta aataaaatta atagcaaaat
    58381 aaattaaaat tattaaaata aaatcattaa taatgagata aatatgttaa aattaatagt
    58441 gtagagtaaa attattatgg ctaagtttaa gtcaattaat ttttagtaaa ttttctaaaa
    58501 agagaataag tgatactgat agaccatata aaaatattaa taaagcataa taagattaaa
    58561 atgagcaaag gaaaaacgct tgttacagcg tatagtatta agaatactta gaaaataaga
    58621 aaggagaaag ttactgcaaa aaagtaacat tataaatatt gagtaatatt tataagtttt
    58681 cagtaacggt gggtagtgta atgaacatat tattctttct aacaccaaaa agtgaagtag
    58741 catatatata tgaagactac actataaggc aagccctaga aaaaatggaa tatcacaaat
    58801 actctgcaat tccaataata agtaaggatg gtaaatatgt tggaactata acagaaggtg
    58861 attttttatg gacattaaaa aatgatttaa atctggactt aaagggattg gaagatgttc
    58921 cagtgacaga tataaataga aaaatggata attctcctgt ttccatcaac gcagatattg
    58981 aagatttagt tataaaatct ttaaatcaaa atttcattcc tgttatagat gaccaagaca
    59041 catttattgg gataataaaa agaagagatg taataggtta ctgttatgag ataatacgtg
    59101 gatataaaaa tttagctaat gataattaaa aatcttattt aaacttttaa gctgagttct
    59161 ttacaataaa agaatgataa tatgaaactg aatatttaaa ctttaatata aaaagctgtc
    59221 ttttctaata aatattgtga aaagacagct tttttatata tgaccttatg attaatcgtt
    59281 gtattttaca aggtttccgt acttagcatt aagagcattt atcttatttc cataaacttc
    59341 attttgtttt tgatataata aacttttttc aacttcagcc ttaacttcat caaatgtaga
    59401 ctctgtactt tcttgaaggt cttctaattt tattatatgg tatccaaatt gagttttaac
    59461 tggttcactt acttcacctt tagccataga gaacacagct tcttcaaatt caggaaccat
    59521 ttgtcctcta ccgaatgttc ctaaatcacc acccatatct ttagatgggc aagaagaatg
    59581 tttaagagct gcatcttcaa aagatatttc ttctgatttt atttgagcaa gtatttcttt
    59641 agctttttca tcactatcta ctaatatatg tttagcagtt gcactttctg gtttagagaa
    59701 agagctctta ttagcttcaa agaattttac tttttcatct tctgttacat taacactaga
    59761 taaaacttta tttatagcaa attgctttaa tacattttct tctatctttt tcatttctaa
    59821 tttaaatatt tcttcttcat ctaatttttc ttctttagca tctaagaaga ataattcttg
    59881 attcactaaa tcatttaata agtgtttttt tccttcttca gttttaaatt gcatagcttg
    59941 ataagggtct aatgatttta atgcattttc aatatcaata ttagttatct ctttttctcc
    60001 aactgttgct aaaacttttt tttccataat agttaactcc ttcatagtgt atttcattat
    60061 taatataaga ctaccatctt aaataatatc agaaaataat gtagatgtct aatatttaaa
    60121 gccatattaa gtcaaataga attaaattta gtagaacaaa gttattacaa ttaataaaag
    60181 tgagctcata atacccacta caccttcgtc atctttaaat ttaagagttt ttactattga
    60241 ataataaagg tatattccag taaaaataat ctttaaatac aagaaaaata aactctttgg
    60301 gtatattaaa aagctaaaaa gtgtaaatat aaaagcaagt agagtactta tcctgtaaaa
    60361 gaaatctatt tgtgtaatgt ctttatattt tatcataaac accgaatata aaatgatgaa
    60421 aacaattgcg acgattgcat atatggtaaa taacatattt tcaagagtac catttgaaat
    60481 tactatccac ttataccaca taattggcca aaataatagt gctaagaact taaaataatt
    60541 atcaaacaac ttttctttat acattcatca aacaaccttt cttaacaaaa gcatatattt
    60601 gtttttagaa ttttaaataa tatgatatca ttattatata ttaatattga atttatagaa
    60661 accaaaattt gttaaaataa atatatagat tttactgtta agccagttaa aattactact
    60721 atttttatta tgaaattgga tcaaatatgt agaaatacgg caaattagtt aatattaaat
    60781 atttattatt tccaagttgt aaagactgtt tttttaatga taaaaattct aatctttttt
    60841 gaaagaaagt aatatccaca ttaagtatgt ctgccatttc ataaacgcag gtgatgccag
    60901 agttaattat gtttattata tcttcttcag taattaagaa ctcacaagcc cattttaagg
    60961 ctttattttc gcacttatct ataataattt ttgtataata atcgttataa gaggatacat
    61021 agtatccaag gctagtgaaa tgatgtccaa gttcttcagc taagatggat gtcaattttt
    61081 ttgagttttg ttttaaatta ctgagtaatg atataatttt aataccatgt ttgtttatat
    61141 atagtccttc taaatcacct gcaatataag tggtataatg aattattatc tcttcttgag
    61201 aagctaattc aaaaagctta tccaaattat tcataaaaat ccccctaaaa tagaatgtat
    61261 gtttgccttt aaattatatt aaaagagcag aaaaatagac tgctcatcat atggtttatt
    61321 tttttttata tttatttagt aaaaattcta tataatcatt aagttgttct tgtgcttctt
    61381 caggtaactc ttcatgtgga ttttttctat gtgcagctac tgtatcaata ttttccttaa
    61441 ctaaggttct tccaagaagg taatcaactg atacattaaa tacatcagcc aatttattta
    61501 aaatgtgttc atcaggaaat ctgttttctg tttcatagta gcctaagact ctttgggaaa
    61561 cgcctacttt ttctccaagt tctctttgag tcaatccaaa ttcctttcta agttctctta
    61621 atcttttggc aaacattata acaccacctt atgtatagat tataacaaat tgttctaaaa
    61681 aataaaacta ataaaatata aaagaatatt tttttctaaa atctattgat aaagaacaaa
    61741 taattctata taatctaagt gaagaagaac aaaatattct taatagtaat ggaggtataa
    61801 aacaatgttt aaaaataact tgaaatatta tagaaaatgc aaaggtatga cacaaattca
    61861 acttgccaga aaggctggaa ttacaaatga ttatatatct caaatagaaa gaggcataaa
    61921 aaatcctgga cttcttatgg ctaagaagat ttccagtatt ttagaacaaa atatagaaga
    61981 agtttttttt atacagttat agaacaatat gttcttgaaa gctatgagat tagtaaaaaa
    62041 ctgtgcacta aagagattat tgtaaatttg aggctaataa taagtatata aaaaagggga
    62101 agtactatgg aaaacaaaaa agatatatta tttaaagaaa cagataaaag attacataat
    62161 tataagtatt tggatataaa gataaagaat attaacttgg acataaaaag atgtgagaat
    62221 gaatactctg gatgtggagc aatggtatat acagaaaaga ctagtaacac atataacata
    62281 agctcttctg tggaaaatga ggtgttaaaa agagaggaaa gattaagaaa attaaaaatg
    62341 gaaaaagaag atatagaaat agaaaaagag aagatagaaa atgctctaac gtgtctaaat
    62401 gatatagaaa tggaattttt taatcttttt tataatagta agacaaaaaa caatatgaca
    62461 tatatttcta tgaaactaca cttagataga acatcttgct acaatttaaa gaaaaagatg
    62521 atatttaaat tgagtgagat attataaaaa ataggacaat tttacaacac tttatataca
    62581 ccattgcaac aataggcaat aaaatatgtg agataatgtt attgtgaaag aaatccatat
    62641 tgaaggaggt gatagattga aaagaataat attacctaaa aatatagaag atacttgaca
    62701 ggaataaatg agatatatat ttaaaaatga cttatatcat ttatagtaag attatcagat
    62761 taagcaagaa tatttagtga tagtgtggtg attatttgct taaatacaag gaaatattag
    62821 aaacaattat tgagattctc aaaaaaaact ttactgaaag tatttttatt gatgatgaaa
    62881 gtgtgcaagg ctctgaaggg tcttgttttt ttgtaagtat actatcagtt atttgtacac
    62941 ctgtaatgtt aaatacgaat aacaaagata ttgttatctc tataaaatac ttaccaaaac
    63001 cacagtcaaa gagtattaga atgtatgaag tttcagatga attaaataag ctatttaaca
    63061 gaaatataaa ggtaacagac agaaaattaa atataacaaa gctagaacaa agtattaaaa
    63121 aagaagagtc aatttatgta ttgaacttta cacttacact aaactatctg gatagtgtat
    63181 atgaagaaga tgtagtatat gaaaatatgg aagaaatcaa tttaaattta ggagagtgat
    63241 agtatggcta taggattacc aagtatcaac atatcattta aggagctagc tacaactgtt
    63301 aaagaacgtt cagctagagg aataattgca atggtgctta aagatgctaa ggcactaggt
    63361 cttaatgaaa tacatgaaaa agaggatata ccagttgatt tatctgctga aaataaagaa
    63421 tatataaatt tagccttgat gggaaatgtt aacactccaa ataaattatt agtttatgta
    63481 atagaaggag aagcagatat tcaaactgca ttagattttt tagagactaa ggaatttaat
    63541 tatctatgta tgccaaaagc agtagaagct gataagactg ctataaaaaa ttggataatt
    63601 aaacttagag atatagataa ggttaaggtt aaagctgtat taggaaaagt tgtaggaaat
    63661 catgaaggga taattaattt tactacagaa gatgtgttag ttggagaaaa gaaatacagt
    63721 gttgatgagt ttacaagtag ggtggctgga cttatagcag gtacaccttt aagtcaatca
    63781 gtaacttata ctaaacttag tgatgtagtc gatataccta agatgacgaa agttgatgca
    63841 gaatcaaagg ttaataaagg agagcttata cttattaaag aagcaggagc tataagaatt
    63901 gctagaggag taaattcttt aactgaatta acagcagaaa aaggagaaat gttccagaaa
    63961 ataaaaatag ttgacacttt agatattata catagtgaca taagaaaggt gataatagat
    64021 gactatatag gaaaggttac taacagttat gacaacaaat gtttattgat agtagctata
    64081 aaaagttatt tagaagaatt agaaaaatca gcacttatag aatctgattc tactgttgaa
    64141 atagattttg aagcacaaaa atcgtattta aaatcaaaag gagtagattt atcttatatg
    64201 acattacaag aaataaaaga agctaacaca ggttctaaag tatttttaaa agcaaaaata
    64261 aaagtacttg atgctatgga agatatagat ttatcaatag aaatatagga ggattattaa
    64321 tatggcaaat atggaagcta gaaatgtaat gagtggtact tggggagaac tttggcttga
    64381 tggaaacaaa gtagcagaag taaagaagtt tcaagcaaag atggaattta caaaagaaga
    64441 tattataata gcaggtcaaa tgggtactga tacaaagtat atgggatata aaggaaaagg
    64501 ctcaataact ctataccatg ttagttcaag aatgcacaag ttaattggag aaaagataaa
    64561 gagaggttct gaacctagat ttgttgctat atctaaatta aatgacccag attcttatgg
    64621 agcagaaaga atagcagtaa agaatatagc atttgatgat ttaactttag ctgattggga
    64681 ggttggcgta aaaggagaga tagaagcacc tttcacattt actgagtatg attttcttga
    64741 tataatttag ttttatattt agttttatat ttggttttat actgatattt agtaaatata
    64801 tacttaataa attcagatag ttaataagta aaaaagttag ttgattgaat ttgattgata
    64861 aaggagcaaa taataatgag tgaaaatgga ttatcaaaaa atataaacat agtagattta
    64921 cttttaaatg cagatacaga aaacttagaa agaccaagta ctatagttga acttaagaga
    64981 ttatcaacta tatttgggca ggaatttaaa gtaatgtgta gagctttaac aataagtaaa
    65041 gatgaagaga tacaaaatac ttgtcttaaa attgatgaaa atatgaaaac ggatatagac
    65101 ttaccggaga tgcagatgct tacaattata gaaggtgttt gtgatttgga tggaaagctt
    65161 ttatttaaaa ataaggagct aatggataaa tttaaggctc caacaccaaa agaattagca
    65221 agaaaattgt tattaccagg tgaaattacc aacttatata gaatacttca agatgttatg
    65281 ggttatggta aaaatgcagt gatagaagag gtaaaaaact aatagggacg gataccagga
    65341 ctacaataat gtactattat tggaagaaaa aaggtataag accgtccctt ttttatgcaa
    65401 tggataaagg cgaattaaag cttattgaag cttttttcgc cttagaaatt gaggaagaag
    65461 ttgaaaaaat gaaacatgga tatggagtgt gtcctttgac aggaggtggt atgtaatggg
    65521 aaatgtgaga gaagaaggta taaatatgta ccttacagat aattacacac caaaaatgaa
    65581 tcaaattata tcagtaactg ataattttag gagagcaact gtggctgttt cactttccac
    65641 taatgtaatg gctagtagca taaaaaattc tattggaagt gcaagtaata gagtaaacag
    65701 tttaaattcc tcgttaagaa aagttcaaac tactgctagt agtgtaagtt caactatgac
    65761 aaaattaagt tctagcataa atgctgtttc aggagttatt ggaagtttaa atggaagtat
    65821 tatgagacta gcaataacta tagctatgat tattgattat tttaataagt tgattcaaaa
    65881 gaaaaatgag tttaattcaa atattatgat tatattaata tttaaagcta aaagtgatga
    65941 agtagaaaaa actaaaaata aattacttgg aaatttaaaa aagattggtg gcaagatttg
    66001 gaatatcgta ataaaagcaa aagatatgac taagagagtg ataagtagta tcttgggaaa
    66061 attaaaacaa gtagagaaac gtccttatca aggaagcatt aatcttaaag atatggtgag
    66121 tagtgctatg gctagaattt tgcctaagtt aatgttgttt aaaaatactt tttggagtgg
    66181 tgtaatagct ataaaagata tggcaagtgg cattataagt aaagtatttc ccaaattgag
    66241 attatttgca ggtaaggtat ggagtggtgc aatagctgta aaggatatgg caagtggaat
    66301 acttggttcg ataaaaggga agatatctga tttgacaaat ggtgctacta taggtgtcgc
    66361 tgtgaaaaag ggtgttgatt tacttggtca ggaacaaaat cagaaagttg ttctagaaag
    66421 tgtaatgaaa agaaatactg gaaaagttaa tcaaatagat gttgatgatt attatggcaa
    66481 tttagtaaga atggcaaatg atacgccttt tgaccctgaa gatgttgttg caatgggaac
    66541 taaagctaaa atgattagta atattactgg tggcaaaaaa gaaaaagata taactcaagc
    66601 tatggtagat gttagagctt taaatatgaa tacaagtagt gaacaagatg tatcagcagc
    66661 tttcttaagt gcagcaaaag gaaacatgga atctcttaat actctggtag gagaaaatta
    66721 taaaactttt gatgaagcat tggaaggcat aagtgtaaag cagatggggt tagctaaaga
    66781 aatgagtaat acaataccag gtataatatc aggagctcaa acaagcatta acaatggctt
    66841 gaagagtatt gttaaacctt ttgatgatat tttaggtcaa ggactaaaga aaataaaaac
    66901 ttttatagaa agtggattag gcaatttagc tggcttatct gaaaaaatgg ctggtaaaat
    66961 aggcaatgta atgaatggta agataattat tggcaacaaa tatgaccaga tgcaatctag
    67021 aagtgtaaaa aatggaaaag agttttctga ttctactcaa tatcgaattt ctaatgaggc
    67081 tgaaaagcgt aaaatgatgg ttgaaaataa gcaagaacgt tttgaaaatc atgcagcaac
    67141 aatgataggg aatgcaccaa aagcaattgt taacgcagga agtacactat tacaaaatat
    67201 cgattttaca gcattaatag attcattact tccagtagta aacttagtaa ataatttact
    67261 agatagtata aacaataaat caccaattgc acaaggatta ataagtatat ttggtacaat
    67321 agtaactaca gcattccaac taatcggacc tgtagttgaa gctgttagtc ctattatcac
    67381 aagaattttt acttttttag gtgaatatgc acctcaaata aacaatttta tagagacact
    67441 gggtgttatt tggaaaactg tatgggagac cttaggacct ctgttggaaa ctggatggaa
    67501 aattatagag ccaatattgg gagctttttt taacatatta gataaagtat gtaaaatagt
    67561 taaagatata tgcaagtggt ggcaaactat gattaataag ataaaaaatg gaagcatcac
    67621 aggaacagtt ttaaatctag tggaaaagag taaaaaaaat tacaaagata atccatatgc
    67681 tggaacaaag gctggtgatt ctggtaaagc ttattcaggt aagaaaggta ataatgcatt
    67741 tggattgaac tatgttcctt ataatgacta tcaaaccaga ctccatgaag gtgaaatggt
    67801 tttaactaaa caagaagcaa atcaatatag aagcagaaaa aatggtggaa atataaacat
    67861 agctaagtta gctgatacaa tagtgattag agaagaagct gatatagaaa agataacatc
    67921 aaaattagtt gcaagtatcc aattggcaca gttagggggt gtcttataat ggaaatgtgg
    67981 cttagacaag ctgaagatag atttagattt ccagtatttc catcttcctt tagtattaat
    68041 ggaaaagctg ctgtaaactc ttctagtata ctcaaaatag gtgaaatagc aacttttggt
    68101 ggtgtagctc ttaaaagcat ttcaatatca agtttttttc caaataaaga ctatactttc
    68161 tgtgactata caggttttcc atcaccatat gattgtgtaa ataagataga aaaatggatg
    68221 aaggaaggtt ttatattaag atttacaatt acggaaacaa atataaatat ggaagtcata
    68281 attgaagggt ttagttatga agaaagagat gggactcgag atgtatattt tacattagat
    68341 ttaaaagagt ataaaagaat aaagatacca aaagtaactc caaaacaata actattatag
    68401 ataataagtt ataaataact gctgatagaa ttaaatgaaa aggcaggtga ttttttatta
    68461 ttaagatttg ggtacacata aaaaacggaa gtatatatga cataactgac atagtagaca
    68521 aggtatcatg gtcaggtgat tataaatctc catcaaggac actagagttt tcaataatac
    68581 aatcatcatt tgatgtaaat ttccaacaaa tcgatatacc aatagctagt acagtctgtt
    68641 tctatgtaga tgagaaagaa ctctttagag gaatgataat taataggtct aaagattcaa
    68701 gcagtaatga aattagtttt gtatctaaag atatgggatt tttacttaca caaagtgaag
    68761 tgtcatacaa ttttaaagat aagttagttg aagacatagc aaagcaagta tttgctgaaa
    68821 ataggctttc agttggcaca atagcaaaga ccaatgtcaa gtatacaaag atgtttatag
    68881 gagtaaatgg ttatgacaca ataatgagtg catatacaga agcaagtaaa aagacaaaga
    68941 aaaagtatat gatagaggcc aatttagata agtttaatgt tattgaaaaa ggaactgtta
    69001 cattaagtgt tatgtttgaa gagggattta atattataaa taccaccttt tcggagagca
    69061 tggaaaatgt aaaaaataaa gtaatagtgg tagaccagta tggaagcaag attagcgaaa
    69121 aaatagataa tgaaattttt aaggaagtaa atgtaataat gcaaaaagta attcagcaac
    69181 aagaaaatca agatgtagat attgatagcg agtttaatgg gatagaaaaa agctgttctc
    69241 ttaaaggtta tggagatgta agttgtataa ctggtagagg agtaaaagtt aaagattctt
    69301 atacaaagct tgtaggacta ttttatatag atacagacaa acatacttgg caaaatggag
    69361 aatatcaaat tgagcttgaa cttaattttc aaaatcttat ggatgaaaag tcagcaggac
    69421 aggatgaacc taaggaagaa agtaatttag ggggagaaga ttatgcagga ggaaaagagt
    69481 ttacagcaga atttacagct tactgtccta gaaaagaaga aggtggagat acagattgta
    69541 gaaagaaaaa acttgaccca tctaaaaaaa cttgcgctgc tcctatggtt ggtaaatatg
    69601 agcaaactta ttatacaaaa gagtttttaa ataaacatcc tttattaaac tatggagatg
    69661 aaatacaggt aattacagga gtttctggtc gtgatggagt ctataaagta aatgacgtag
    69721 gacctgcaat aactatagaa aagaatggaa cataccatat agatatttta tttggaaatg
    69781 ttgaagaagc tagtaaattt ggaagaagaa aaggaaaaat tattattggt ggttattctg
    69841 gtaatgtatc tgataaagct aaaatagtaa tatcagaagc aaaaaaacat ctaggtaaac
    69901 cttataaatg gggtggaaat ggaccaagta gttttgactg ttctggttta atggtctatt
    69961 gttttaaaaa agttaatgtt agtttgccaa gaacgtcaaa tcaacaatct aaaaaaggca
    70021 agaaagtaga acaaaaaaat cttcaagcag gagatttagt attttttcat aatccagtca
    70081 gccatgttgg attatatata ggtaatggag aatttttaca tgctccacaa aaaggtgatg
    70141 tagttaaaat aagtaagtta agtagtagaa gagattttaa cacagctagg agagtattat
    70201 aaaaggatgg tgatataatg gctaatccaa taaatgaatt tataggaata ataagagaag
    70261 aaggaaagta tcataatcaa ccttcttttt ttattggaaa aattaaaagt aaattaccag
    70321 atttaaaaat agagacaaat aacatcatat tagaaaaaga agatattttg atagatagtt
    70381 ggatgattga tagacagcta gaaacatttg acacagaaac aaatcaagaa caccagcatg
    70441 aagtaaaaaa tccttttata gataactttg aatctgggga tatggtaata atgtttagaa
    70501 taggcgaaaa atttgctgtt gtaagtaagt tggtgagctt ataatgagta caatatttcc
    70561 ttttataggt gtcccagagg attatatctt acctaaaaca gaagaattgc caatctttcg
    70621 tgaagtggca tgggattttg aaaaagatga acctatttta gaaaaaggtg actttaaaat
    70681 aattgaaaaa aaagaagcct taaaagtttg gatatacaag tgtataaaga caaatagata
    70741 tgaacatgag atatactctt tagaatatgg gacagagctt tcagaactaa taggacaaaa
    70801 atatacaaaa ggtcttacag aaagtgaagc tagtagattc ataaaagagg cccttctaat
    70861 aaatccatat atattagaag taaacgtaaa aagtgctaac tttaacagag acatattgag
    70921 tgcaaatgta aaagtatcca ctatctatgg ggaggtggaa ataaatgtat agtgaccaga
    70981 catatgaagt aataaaaaat agaactcttg aaaatattaa tcttgatatt tataaaggag
    71041 aaggttcttt tctaaacaac atggtatctg gaaataatct agaactttcg aagatatatc
    71101 tagaactttc aaagatgcat aaaatggctt ttatacaaga cacatataac cagtttcttg
    71161 ataaaagagt caatgaattt ggtgtatata gaaagttagg tacagagtca aatggagaag
    71221 ttgaatttat tggagagaaa ggtactgtaa taaataatgg cacaataata tcatatagag
    71281 atttactatt tgtagtaata aaagatgtaa ctattggtag tgaagaaggt gacaatagcc
    71341 cagttcaaac tctggaagtt ggtaagaaat ataatttacc tacaaattgt gaatttaaac
    71401 tagttgataa tatatctgga gtaacaaaga ttactaacac aagaagtttt gaaggtggta
    71461 cagatataga gacagatgaa gaactaaaag aaagatttta taaaatccaa agaaatcaag
    71521 ctacaagtgg aaataaagct cactatgaag aatgggcttt ggaagtagat ggagtctata
    71581 atgttaaggt ttatccaaga tgggatggtc cgggaacagt taaggtcttg atatttggga
    71641 aaaataatca agctgttgat acagaaacaa ttgaaaggtg tcagcaacat atagatgaag
    71701 agaagcctat tggaccaact ataacagttg tgacaccatt accaatagaa ataagtataa
    71761 gtgcagtaat gaaactagaa gatggatata cattagacaa tgtaaaagaa tctttcctag
    71821 aaagtataaa tacatacttt agagatatta gaggagagat aatctataca aaagtaatgg
    71881 gaatacttat aaatactact ggtgtacacg atttaagtaa cctacttata aatggaagta
    71941 cagataatat aactattaat gaagataaaa tacctagtgt aacaactgtt aattttagtg
    72001 aggtggaaaa tcaatgaagc taattgataa actaccatca tttgatagaa attacattgt
    72061 agaggagata caaggtgcat acgatacaga attaaatatt cttaaagaag atattgatga
    72121 tacctttaac caattatttg ttgacactgc aacatgggga ttagatatgt gggaagacat
    72181 actctgcatt gaaaaaaaag aacttgattt tgacacaaga cgtagcaata taaaagctaa
    72241 aatgagaagc agaggtacta gtactattga agttataaaa agtatatgtg aggcatatac
    72301 aaaatcagaa acagatataa aagtttatag tgatgaattt acattcgtat tgagttttat
    72361 agcaaataac tgtgactata aaactctttt agattgtagc gatatgattg aaagagtaaa
    72421 acctgctcac ttattacact atttagaacc aataatacta gataaaagta tggtctattg
    72481 tggtggaggt atggtatgta gtgaagaggt aaaagttcat ccatactttg aaccaattat
    72541 aaaatgtagt gctgttgtaa actgtggagc tggaatgtta agtagagaag aaataaaggt
    72601 ttatccttta agtattaaat gcattgaaaa taattgtaag attaatatag ctattgcaaa
    72661 tgatacaggc gtagaaaatg tagtagttta tcctaaatcg gaggtggtat aattggaaga
    72721 aaaattttat ataatattaa ccaaaattgg tagagaaaaa atagcaaatg caactgcact
    72781 aggagagctt gttggattaa ccaagtttca agttggagat agtaatggag aatattatga
    72841 gccaacagag gaacaaactg ctttaaagaa tgtagtttgg gaaggaaata taaattctct
    72901 aagaattgat gaaaaaaatc ctaattggat agttatagag actattttac caggaacagt
    72961 tggtggattt atgataagag aagctgctgt tctggataat gagaataata taatagctat
    73021 aggtaagtat ccagagacgt ataagccacg tgctgaagat ggcagtatta aagatttggt
    73081 tgtaaaaatg attttacaat tgtctaatac ttcaaatgtt acattagaag tagacccgac
    73141 gttggttttt gtaactcaaa aggatattca agatttagat gataaggttg ataaaaatat
    73201 aaaagaaata aaagtaaaaa ttggagaaga actcttatct acagaagcta aaaacttatc
    73261 aggagctata aatgaggtag tagaaaaaat taaaaatata tctattgatg atgtaatagg
    73321 aggtcaaata caaactgaac tatctgtatt aaaaaatagt tacaataaat tatctgaaaa
    73381 agtattagat attttaatat acttagaatt agagtcagaa atagatgtag atgaagctgg
    73441 atattggtat gataccttaa ctaatgctaa aaacataata gctatagaag gccttaagtt
    73501 agatttaaat agaaagtgta taactggaga acttggtagt gttacattta agaatgtggt
    73561 gctaccattt aatgcaaata gagttagata tatacatgaa atggataata actttgttga
    73621 aacaaaatct aatagggcat attcaattgg ccagacagat ataactttaa ataaatattc
    73681 gtatgaaata agataattag gaggttttta taatgaaaag aactaaacta cttcaaagag
    73741 gtaatttctt tggcgataaa aatatgttag ttgatgaatt tgatgaaggg tatgataatt
    73801 atgactttat taattttttt actggatgtt gtaactatac atttggtcta aaaaataata
    73861 atatcttgta tggatgtgga gataatagta actttcaact tggattggga gaagacaata
    73921 caacaagaaa attatttacg aaaataccaa atatatctac taatattaaa aaagttgcat
    73981 gtggagaatc tcatgcagtt atacttactt cagatggaga attacttgtc gcaggtataa
    74041 atacagatgg tcaaatggga ttgggattag aaaaagtagg gaaaacagtt tctacatttg
    74101 agaaggttcc agaaataaaa ggcgtaaagg atattgcatg tggacttcaa tcaacatatc
    74161 ttttatacaa tgatggaact ttatatgttg ctggaaataa tttgtatggt caattaggtc
    74221 taggaactaa tggagcatct gcaaatgtaa atacatttac aaaagtagat gttgacaatg
    74281 taaaggctgt attttcatat aataaatcag cttttataat aaagaatgac aataaatgct
    74341 attctactgg ttttaataat caaggtcaac taggtttagg agataagaat aatagagatt
    74401 tatttagttt agtttctatt aatgatgtta agactatagc ttgtggttct gaacacactg
    74461 tgttaatgac gtataataat gatatatatg gttgtggaaa ggaaaaatgt tttggaaatg
    74521 cacttcaatc atcactattt actaagatag aagaagtaaa tataaaaact attgcatgtg
    74581 gtaatggtaa tactatgctt atagataata aaggtatttt gaaggttgct ggaaataatg
    74641 atatatatca gttaggtata gcaaattact ctgagaatat agataattca tttatagatt
    74701 taaaaaatat tgtagctaag aatattttca ttggtttatc acatagcata ctaattgatt
    74761 caagtaatga ttcatattgt acaggagata atacttatgg acaattaggt tcgttttttg
    74821 atgatatgca cattgtagaa tttaagaaaa tggatagtga aaaatatagt tatagtaatt
    74881 atataaattt aattaaatct gaggataaat taactttatt aaaagaagaa atggaaataa
    74941 aggatattga acttccacta gatatacatt ctgtaagaga tgtcgttttt agtccttatt
    75001 gtactctggt tattttaggg aatggagatg tatatggtct aggaaataat agatacaaag
    75061 gaatgggttc tgacttacca attcaattaa atgagttgac aaaattaagt atctctaatg
    75121 taaagtctat agtagcatca aaaaatattt ctggaggaat attctacatt aaaaatgatg
    75181 atacttgtta ttattctgga gcaaatagta actcaatagc aggtgttctt ccttctaatt
    75241 cagatgtatt taagaaaata tctatagata atgtaaaaaa agttgttata aatactgatt
    75301 tatcaaactg gttttcatta attgtaacta ataataaaca aatatacact tctggaaaga
    75361 gttcaggtta tgttaatgga cttagtaata aatcagcaag tcaatatact gagattggtg
    75421 ttagcaatgt aacagatgca tatagttcat ataatgcaac atttattgtg gctgacgaaa
    75481 aaaaggtata tgcaactggt ataaatacaa actatttatt gggtgttaat cctaatgatg
    75541 gagtcaatat aaatttaaca ttaataaata actggtttta tgtaaatcct tcaggagcaa
    75601 gttatagtac aaattcttgt acaaatgata ttactaaaat taataatatt attatatatg
    75661 aatatatggc tatattatgt acaaattatg gttctttttt aactggatac catggtactt
    75721 tatggacaaa gccaagtgat tctacttata gagttcaaca acaaggaatt acacatgctg
    75781 gatatattag taattacata tataactatt atcccacaag gtgtacacaa tcatcatatt
    75841 ctacaaattt tgcctatttg tattatggag aatcaacaag taatttaaaa aatgtaaatc
    75901 cagataattt acttatttct ggaggttcat cttatataca tcaatatgga aggaattatc
    75961 ttaacaatca atcatctaat aatattgcag catctaatat aaattcaggt cctattacct
    76021 ctgataaagc catattttta tataaagctc tattgtattt atcttctaac acgctatatg
    76081 gttttgggaa tatatctgaa agtgcaaaag aactagatgt ttcagataca caagatggat
    76141 ataatgccac taattataaa aaggtaatga aaaatataaa aaatatattt atacctcctt
    76201 atgatttaag tagagataaa actagatttg caatattaac tgataagagc ttatttatat
    76261 gtggatataa ctctaagggt acgcatggta tatcagttaa tagtagttta aatttaaata
    76321 ataagataaa ttacaataaa aagaatagca gtagtgaaat atcttctaat atacaagaaa
    76381 tatatagcca ttcaaagtct acatatttat taactaataa taatatgctt tacagtgttg
    76441 gtttaaatga tgtaggtcaa ttaggagtgg gagatgagat aaatagaaag gtatttgcta
    76501 aaataaatat tgataatata aaatctataa gtgtaaatag atttactgac aacagtaaac
    76561 atgcatttgc tataaaaaat gataatacct gttatgctgt tggtttaaat aattctggtc
    76621 agttaggaat aggagataat gtaaatagaa atgtatttac taaaataaat gttgaaaatg
    76681 taaaatatgt aactatatat ggaaacacat ctctattatt aactaatgat ggtcttttat
    76741 atggagcagg taataatgga aaaggacagt taggattggg tgatactaca agtaggaata
    76801 tatttacacg tatacctata aatggtgtta gagatgtata tctatgtaat gatgtatcaa
    76861 tcattgtcaa aaatgataat acatgttatg tatgtggatt tgtaaatgga tattttggat
    76921 tcactgaaag tagtataagt acatttacaa aaataaatat tgagaatgta aaatctgttg
    76981 tgacagcagg aagtgaagct acatttttta taacaaatga caatatgatt tatactacag
    77041 ggaaaaaaga gagggtattc ttttcaacag aaactaatga tataaagggt atacgagtaa
    77101 ttaataatat tataaatgca aaaaaaatag tagttaatgg atatacttca gccattttaa
    77161 caaatgataa taaactattt gttggaggtc ttagtggata tggaagtata acaaataata
    77221 acaatacaaa tagtgtggaa gatgttaaag atgtttttgt gacagctaat aatacacttt
    77281 atatagataa taataacaat ttgatatcat caggtagaga tacttatggc atatctgatg
    77341 agtattatat ggatatacca gttccatatt ataaagtatc tataaagaaa gatgttgata
    77401 ctgtattttc tagttacaat actatattta ttaaagatat atatggaaaa ttttattctt
    77461 caacaggaga taacagatat aatcatttag gtattcacca tagatatgat aatgataaaa
    77521 atgaagctct tgaaggttcc ctacattcat attttaaaac agataacaca tcagataaaa
    77581 tagtttttaa taagaaaaat gaaaagctag taatgtttaa tgataagtat ataaaaacaa
    77641 ataataagta tataaattat aaaaacatat ttaaagataa ttttaagtat acttcaataa
    77701 tattgccatt tgaggtatct gatattgata tatcaaaaac acattcattg gctgttgcta
    77761 aggatggaaa attatatgga ataggaagta attcatataa agaaattaat caaactcttg
    77821 aagatataga attattaact tttactgaag taaatatatc agatgtcaaa aaagttgctt
    77881 gtggagataa ctactcctat attattaaga cagataatac tctatggtca tatggaaaga
    77941 atactgagta ccaattggga gttggtcaca ataatgatgt aagagagtta caaaaggtta
    78001 ctggattacc ttctgttaaa gatataagta tatataactc aatgacactt gttttaacta
    78061 atgagggaga gttgtacgct caagggtata atacaaatgg attgtttgga ctaggagaaa
    78121 gtgaaaaaga taaaataata acaactttta ctaaagtatt aactaatgtt aaagaaatta
    78181 agtcacataa tgatgaccac atactagtaa ttaaaaatga taatagtcta tggataactg
    78241 gtaaaaataa atctatgtat aaaatatcta tatcaattac tgatttatat gaatttacta
    78301 aaataccaat tcctgaacat ctaaatgata ttttagatat agagctttca gatgatacaa
    78361 tatacatgat aacaaaagta gatacaagta aagcatctat agaaatagtt gaaaaatcaa
    78421 tatctcaagt gagagttgta gtacaagatc ctaataatgt tatagaaaaa cttgaaatgt
    78481 ttataaatga tgaattaata tctactaaga ctaatttgga aataaatagc attatatttg
    78541 agataccaca aaataaaata gtattaggag aaaataagat actgattaaa gccagtagtc
    78601 ctacaggcga tttatattca agtatgttta tatttaaatc agaaacaggg cttaaagtaa
    78661 aaaaggattc tattttaatg ataaacaata aagtatattc aatcataaac attactgaaa
    78721 ataacactga tttaatagta acattaaatg agggattaaa ggatgatatg atggaaaaca
    78781 atcctatata tcaattaata aataaaacta aagttcaagt aaaaataaat aaatctgact
    78841 tattcaaaga catgaaacta gttgaaatca aaaaatcaga ctcaagttac caagaaatct
    78901 atgaattaga agaagccaac ataaaaagtg ctcagcctaa aatcatagta gaaaaaggag
    78961 ataaatggac agctataaaa cgtccatcta tgatttttag atatgatgct gaaaacaacg
    79021 agccacaagc ttaaaatgga ggtgtgaaaa ttgtttaaat tcgataaaaa taaaatagaa
    79081 caaatcaaac aaggtagaaa agtagaaatg cagtataaag acatttcaga cataagtata
    79141 ggtcaagtaa agcaagatga tgatataaca aataatttta tagcaaatgc agaaatatat
    79201 gagatgttgt taaatcaaag ttctgtcaat gaagcaagta atataagctc ttttagtgta
    79261 agaaaatctg gaggtgagag tggaatggta gaagtatatg tagctttaat tttaagaggc
    79321 aaaaaaacaa tagaagaagt accagcagta attagagagc aagttagaat tagatgtaaa
    79381 gaattagaaa taccagttga atagtaaatt tagaataact atatactagt tatttttttt
    79441 atgtaaagta caaggtttta actttaataa gtaagccttg tacttatttt ttgttatatt
    79501 agaaattgta tatatattta ttatttattc aatttataaa ttaaacctac aatttaaagt
    79561 acagaagatt aaattgataa tcctgaaaat ataatattgc atgatgtaag aatacaacaa
    79621 aaattaaagc tataagtata aaaaatttag acaataggag gctataatgg ataaattaat
    79681 aaccgaattg agtagtctag gggcaatagg tatactatgt gctctattat ttaaaaatac
    79741 tatgcaggag aaaaaagaag atagagacat gtataaaaaa actgtagaaa attttataga
    79801 attatctaca caacaacaag aaataaacaa aaatatactt gttcaaatgg gaataatgaa
    79861 aacagatgta gaggaaatta aggaagatgt tactgatata aaaggtatgt tacaaaacgg
    79921 tgtataacat gaaagagtag caccagatta tatattgtta ggaaaagata aagtagtatt
    79981 gtagatagtg cactatttta ttgagaagga tttaatattt aaaaatatta attaaaaaaa
    80041 gtaataaaaa taatatataa aaattaaaaa aggagttgag cttaaatttg attagaaaaa
    80101 atcaatttta agacaactcc ttttttttat taaattattg tctattaacc aaaatagcta
    80161 ttttagcatc tggattataa cttatctgaa ccatttgatt tttcttaaca tgttcaaggt
    80221 cttcaccacc ataagctatt tgtaacttaa ctggtaactt accttgtttt ataatagcaa
    80281 cgtactcttt tttacctttt ttctctaaac taatcaaatt gccaacataa ggtttaaagt
    80341 tctgatactt tttactagaa tttcttatgt agaagaaagc accaacagca ataactaaat
    80401 ttatgccaag tgtaacccaa gaattgattt taagcatagc tccagcgatt attatcacga
    80461 acattaaaac gataggtaat atagctttct taagaagcaa tttacccatt atttcattag
    80521 cctttttctc agggccactc atagtttttg atctagcaaa tgattgcgcg aatttgtctc
    80581 ttaagcccat tttatcctcc taattttaat aaatatttag ttataataac gagatattac
    80641 ttgaaactaa aaatttacta catttatatt atgtttgact tttgtataaa taattacatt
    80701 caagtaaagc aaaatatact aattatttta tcataaaatt ataaaaaaga aaataaatga
    80761 aataaaaata ttagaacaaa gaaatgatgt aaaatcgtat caaaagcaac ataaaaatta
    80821 tttatctatt ttctcatctt tatttttgtt atactcaatt tttcctaaat ccttctcttt
    80881 ttcatattca tgaagtttta attcgatcat accttctatt ttggctttat cataatcatt
    80941 taactttcta aagttgttta aaagttttat ttcattagag tttatgctat taagtggata
    81001 gtttgaggag gaatcgcaaa ttaaatctga tttatgtgat agattatctc catttaatag
    81061 ccagtctact gaaacattaa atatctcagc tatagatttt aatatttcat aatttggttt
    81121 tctaatgttt ctctcaaatt tacttaagtt gtcacagccc aacatttctt ctagttcata
    81181 ttgtttaagg ttttttgctt ttctcaaata aacaattctt tctcctaaag tatccataaa
    81241 cactctccat tcaattaatg tcaaaaagac tttttaagat gtaaatagtt tcaaattaaa
    81301 ggtcaaaatg acataaaaaa cattgactta aggtcaaaat gactttataa ttaacttaat
    81361 gatacgaatt tacatcctaa ttttagcaca aagtaatcaa aaaatcttat ttagtattaa
    81421 ataaatttat atacttaata tgtgtacata ttaaaaatat atactaaata gagggggtgt
    81481 gtaagctaaa ataatataaa agtaaatata aatcacttag aaaggaagtt gataaatgga
    81541 tgctcgaaaa aaatggatac cttttttggg agtgcaagtc aagcaaagac ttattgaatt
    81601 aaatatgact caaagggaat tagcgaagaa aataggtgtt aatgaaaact atttgtcagc
    81661 tattttaaat ggaagaagaa caggtaaaaa atataaatca tcaatttatc aattacttaa
    81721 tatagaatat tcagaagatg attaataaat agtatataaa gtaggtgaat attcttgtgt
    81781 gtaaattgga ttcagatggg gttatagagt gttgtagagc aattgatgat tttattacag
    81841 cactcagtaa tataaaaagc ttaaatatgg aaagattaaa tactttaact aaatattcta
    81901 gtacatgttc aatccttctt aaagagggga attatgaagg atgtacaatt gtgtatagaa
    81961 agatgttgga agaattaaaa acatgagtaa tgcatttctt aggaatataa gttatacata
    82021 gagatgtatt atatttttca aagtacttaa actaaaatat ggataagata atctaaatat
    82081 tataaatgtg cttgaaatta gactatactt gtttttaaat aatccaatat ccatatttta
    82141 gtaatatact acaaaaaaag aaggttaata gatgatgtaa aatcgtatca aattatgtat
    82201 gtttaaacca ttttatcttc attattatta gaggaatgct tttttaagtc tttatattca
    82261 gatatcttaa gttcaagtat tccttctatt tttattttat cacgttcgtt tagttgtctg
    82321 tatagattta atatcgtcat ttcatcatta gtaacatgta agtaatcttc tttatcttct
    82381 tttacactac tattgacatt taccttctct ttaccataga gaagccagtc agtcgtaaca
    82441 ttaaaataat cagctattga cattagtata tcacaattag gttttctatc tcctgtttca
    82501 tacttgccta agttttcaaa ttttaaaata tccataagtt tgcgctgagt aagttttttg
    82561 gagtttctca aataagcaat tctttttcct aaagtatcca caaaatacac tcctttcttt
    82621 ttatgagtaa tgtctaaatg acatttaaaa ttaaaaatat ataaattcat aatataaaac
    82681 tactaaatta aagtctaaat gacattttgc ttaaattaat atgctcataa tatgatttta
    82741 acatattata gttgaaaata tatggtttat tttgatttgt atatataaca ataggtttaa
    82801 ttgttataaa aatgtaaagg ggtgtatgaa tagattgtat aaatttattt cgataaacta
    82861 agattgtttt ttgattgtct gtaaaagaga aaaagattaa gagaaaaata gtattatatt
    82921 gtaatttata ttaatcaatt acaaaaattt tatgaattta ttctttagga taaaatattt
    82981 aagaataaga taaatttaca atataatact ataacactct tttatctagt tttattttct
    83041 ttatagaaca ataatattat aaatgctagt agatttacac agaatactgt tatatacatc
    83101 tgtttaaatc ctgagtttag agtagattgt agtgtgtttt ctatttttgt tctattattt
    83161 tctatggaat ttatataatc caattttgat ttatcaaaag cctttggtat ttcagttttt
    83221 acctcttgtg tctttgctaa aactgcttgg agtgattttt tttgctgttg cattgtatca
    83281 aggctttttt ccatgtcttt cttttggctt atagaattat ttaacttgct ttgtagctct
    83341 ttcttttgag attccattga tcttagtttt ttacttaatt cgttcttttg agttttattt
    83401 ttttgtaact ttgtatttaa gtcatctctt gtctttttta gttgctgtat ttgagcattt
    83461 aaactttctt tttgttcatt tacatttggt ttattctcac tggaattgtt attcttattt
    83521 tctgtagaat cattcttagt gtcgtctgat tcagaattac tggtattact ctggttttgt
    83581 tcatttgagt tattttcgtt atcagtagga gttttttctg tagtaggtat tttattataa
    83641 gcagttgtaa gttccttgat ggcctcatct tgtttttcaa gaccttgttc catacctttt
    83701 atacctttgt caacaccagc aatacctttt tttacaccat ctattccttg attaatacca
    83761 gctctagctt ttaccatatt gtcaatacca gtttgaactc ctttaatacc actatttagt
    83821 ttattttcac catcttcaat accgtttatt ccactttgtg ttccatctat tcctttttgt
    83881 acatttttct gtattttagt aattatagat ggaacttttt catcaaacat tgttgttgat
    83941 atttcttttg ttatattggt aatgttggtt gtatctgctg actgaacttt attaagtaag
    84001 gattttggaa gtttgccacc tgtcatgtcc atatttatat ttgaagtatc attcatattt
    84061 gggatagaga cattttttaa attttttgcc atttcagggt ctgattttaa gtcatctatc
    84121 atgttttcaa gttcttcaag ttgaactatt ttaggagttg agggctttcc aactaagtcc
    84181 ataatattat cttgcacaga taatcctgca tgtgctataa atccaatcat tatagctgga
    84241 gaaattgaag taccaattga gcgtatcaag gataatgttg caagtgctga attagattct
    84301 tctaatcttg tatttgataa catcatatag tttagaggag ttaccatagt aaatcccatt
    84361 cctaatccca taaatattaa acttacacat acactaaata cagtattggt ttttagagca
    84421 attaaaacta ggtaaagaga gcctatcata gatacagaaa atcctagtaa tagtattttt
    84481 tttgccccaa atttgtcaat aagtcttccg cttaaaggag cagcaatacc tgcaaataat
    84541 cccaatatag ctacaaaata tcccccagaa ccagcattta tctttaatgc attttcagca
    84601 tactgtggaa cgaataccat acccatcatt ccaataccaa caattaaaga taaaataagt
    84661 actatcaata ttctcggatt taaaaaatat tcaaagctta aaatagggtc tttagctcta
    84721 ttttcaataa atatgaaaat aggtataagt acaataaatg tcaataagta tggataaact
    84781 gatatatctt gtatagaatt tttaaaatta aaaaagtcta tattcataag accatataat
    84841 agtgatacga ttatacatat caacatcaat gtaccaagct tatctatttt ttctttagat
    84901 tcagacttat tgtttttaat acagaaaact ccaccaataa gtatgattaa acaaattgga
    84961 agatttacaa aaaatagcca cttccaattt tgagttccaa agatacttag aattgtgcta
    85021 ccaatgcttg aacctaaaat attggcaata ccatatgttg ccccaactaa acctaaagcc
    85081 atgcctcttt tattttctgg gaaggtagtt ccaaattctg ctgtagcaat tggcatgatt
    85141 ccaccaccac caattgcttg aataacacga ccaattaata aaatatagaa attggaaaat
    85201 agtgatgata atccacatat taatgaacca ctaccaaata gaaatatact aactagatac
    85261 acatattttc ttcctatttt atctgctaat tttccagaga taggaattac agaagcgtat
    85321 gttaatgtgt atatggtaat catccaaatt cccgtttttt catttactcc aaggctattt
    85381 tgtataatcg ttcttgctgg tgatactatt ccagtatcaa tagctcccat aaatatacct
    85441 aatagataaa gtgtaagtac taaaaatatt tttggattac tgtccttgtt cttaatacta
    85501 gtattatgat tcaaggtaaa caccacctta atgtattaat ttttcaatat agggttttaa
    85561 atcttcaaat tctatatgaa gatatgttga atatgaaaaa aacattttta ttatgatatt
    85621 gcatactaat ttgtcattat taaaaaaact ttctttttct aaagcttcat atactttatt
    85681 tgaaagctgt tcatgaaagt cgtctttgtg ttttttcatt tcaaaaaatc tctctgtttc
    85741 aaaagtgttt aaaaagtcat tgtattggat attatgaact ttgtttataa aatttcttat
    85801 ttcagtaaaa ataatgttta gtttttttat gtaatcttca gtgtttttat tggagtattc
    85861 aattcgcctt atcaataaat cccattcaga ttttgtgata tattctatta tttcttgttt
    85921 tgaattaaag taattataca ctgtacctgc acttatacca cacctttgag ctattttcct
    85981 tatgctaata ttcgagtaat cttcttctaa aatcatatcc cgagacactt ttaatatatc
    86041 ttcttttaca ttttctaaaa tctttggcat attaccacct cttttattaa aattattatg
    86101 aacactgttt attatactcc tttaaaattt attaatcaat atgtaagcta taatgtataa
    86161 tattattata tagatatgat agaaaataag tgtcttctta ctaaatatct attatattaa
    86221 atttgtactt aagtatgatt atttattgaa atatgtgata ttaaattttt ctttttaata
    86281 aattaaatat tatatgataa ggagaatatg gtgatggaaa agaagtatgt aatggcatta
    86341 gaccaaggaa caaccagttc aagagctata ctatttaata aaaaaggcga aatagtgaaa
    86401 attgcacaaa aagagttcaa tcaaatttat ccaaaagctg gatgggtaga gcatgaccct
    86461 atggaaatat gggggtcaca aagtggggta atgagagaag ttatagaaac agcaggtata
    86521 agaccagaag aaattgcttc aatagggata actaatcaaa gagagactac ggttgtttgg
    86581 agtaggtata ctggtaaacc tatttataac gcaatagtat ggcagtgtag gagaacgtca
    86641 gaaatatgtg atgaacttaa aaataaagga ttggaagaat caataaaaga aaaaacaggt
    86701 cttttaatag atgcatactt ttcagcaaca aaagtaaaat ggatattaga taatgtagaa
    86761 ggagctaggg aaaaagcaga acaaggagag ttattatttg gaactataga tacatggtta
    86821 atatggaatt taactcgtgg aaaagtacat gtaacagatt actcaaatgc atctagaaca
    86881 atgatgtaca atataaatga tttagaatgg gatgaggata tattacgaga attggacata
    86941 ccaataagca tgttgccatt agtaaaacct tctagctatg tttatggtca tacagatgag
    87001 cgcatgttat caggagctaa aatacctatt gcgggatgtg ctggagacca acaagcagca
    87061 ttatttggtc aaaattgtgt tgaagaaggt actgcaaaaa atacttatgg aacgggttgt
    87121 ttcttgctta tgaatacagg cagtaacata gttaaatcta agcatgggtt acttacaaca
    87181 attgcttggg gagttgatgg aaaagtaaca tatgcattag aaggaagtat atttattgga
    87241 ggagcatctg ttcaatggct tagagatgaa ttaaagataa ttgaatctgc aaaagatagt
    87301 gaaatgtatg caaatagggt agatgatact aatggtgtat atgtagtgcc agcatttaca
    87361 ggtcttggag ctccatattg ggatatgtat gctaggggtt caattttagg acttacaaga
    87421 ggagcaaaaa aagaacatat agtaagagcc acattggaat caattgctta tcagacaaag
    87481 gatgttttag aagcaatgca aaacgattca aaattaaaac taaaatcatt aaaagttgat
    87541 ggtggagcaa gtaataataa ttttttaatg caatttcaat cagatatatt aaatgtagat
    87601 atagatagac ccaaaatagt agaaactaca gctttaggag ctgcttattt agcagggttg
    87661 tctgttggat tctatattgg aagaaatgaa attacttcaa agtggtcagt agaaaaagag
    87721 tttaatccaa atatgagtga agagaagaga tgtaaattat ataaaggatg gaaaaaagct
    87781 gtatcgagag ctttaagctg ggaaaaagaa gatgaattgg atatttaaaa attaatcaaa
    87841 gttaaattta tttgaattta aaaagagctt tatgtaaaat atgaagctct ttttttgttg
    87901 ttaattttgc atttttatat aatcacacta aattatataa tttatttttc gttttcatat
    87961 aaaaacattg gtatagaatt gtaaatgtgt tggtcaccaa ctactaagag aatgtctcct
    88021 tctaaaaatt caatatatgg tccaggagat attataagtt cttcacctct tttaattgca
    88081 actattgtag cacctgtatt ttgccaaaat ttagtttgtg cagctgtttg accaatatat
    88141 ttgcaattag aatttatggt gaactgaacg ggcactaaag gattgattat ttcaagtctg
    88201 ttagaatagt ctaaaatttt atttatagta tctaatattt cattttctaa attagattta
    88261 gtatctatta aattataaag tgttgattta tatgatgata tatttgtaat atctctatat
    88321 ttttttataa aagaagaagc tttgtctgga gatagtacaa taacaccttt accctttatg
    88381 cttttaacaa cgccaatgtc ctctaaaatt ttgacagctc ttcttatcgt ttctggagat
    88441 acattgtatt taccagccaa aacagagcgt ccaaatagta ctgaatcctc ttgtatttca
    88501 cccgtgtata ttttatttgc aatatccaac gctatttttt ggtatattgg catcgtatag
    88561 tttttatcca ttgtttttcc cccaatacaa aatttatgtt aaaaaaatat ataatcttaa
    88621 caatactatt gtataattta taggtttata tgtctacaat atgtacaaat attgtgcatg
    88681 ttttaaaata atattttaac atgcatttag tatacatgat tttattatac ttaaaactat
    88741 ataaagaatt aattataaaa atataaagat attttactta caaagaatga taattatata
    88801 gatgaaagaa acaaatgaat gaagaaaaat gattctgtct tgcatataaa gtgattaaaa
    88861 atgaaaaata ctttaaaaat gaaggttaag gcccttattt taagtgaaaa taattaatta
    88921 ttaactaaaa aatggtaaaa agattttttg aaaaagaaat acaaatgaat gttcaattaa
    88981 aataattgca aaaatattcc ttaaatggta aaattatatt aattaaatgc aatagaatag
    89041 ttgcaaaaat aaaattgaat acaagtgata aaatatttca tgcaatatat aaaataaaca
    89101 aaatttaaaa attaaaacta cttattctat caaaatgtta gcgaggaggg gtcataaatt
    89161 gtataaagta gatttaaata gtgatttagg agaaagtttt ggaacgtata agattggttt
    89221 agatgaagaa gttttaaaat atatttcatc agccaatata gcttgtgggt ttcatgcagg
    89281 tgaccctagt catatggaaa aaacagtaca gctagctaaa aaaaatggag tgaaaatagg
    89341 cgcacatcca ggtttcctag atttaatagg atttggaaga cgtgagatga aaataacaaa
    89401 gcaggaagct aaagattata caaaatatca attgggtgct ttaatggcat ttgcaagttc
    89461 aaatggatgt aatatacaac atgtaaaacc acatggagca ttatacaata tggcagctaa
    89521 agataaagag ttagctatgg ggatttgtga agctatatat gaagtcgata aagatattat
    89581 actgttgggg ctatataata gtgaaatgat aaattctgct aaagaaattg gacttaggtt
    89641 tgcaaatgaa gtatttgcag atagagctta tgataataat ggttttttgg ttccaagaaa
    89701 tgtagaagga gcagttatac atgatacaaa acatgcaata gatagggttg ttaggatggt
    89761 aaaagaagga actgtagaaa ctttaacagg tgaagttata catatcaaag cagattctat
    89821 atgtgtacat ggggacaatc caaaagcaat agagtttgtc aaagaaataa gaaagcgttt
    89881 tgaattagaa ggtatagaag tttgtccatt agaaaacata gaagtttgtt cgtcagagaa
    89941 catagtataa gactgataac atgaggggga gataaaatat gagtacaaaa aatattacag
    90001 ataaaactaa aaataaaaaa gatgtcggag cacttatagg ggctgcattt ataatggcaa
    90061 catcagcaat tggaccaggg tttttaactc agactgcaca atttacccaa gattttggac
    90121 cgaatttttc atttgtaatt ttaattacaa caatcctttt tataggggct caagtaaatg
    90181 tatggagagt aattggtgta tcaggactta gaggtcagga tatagcaaat aaaataatac
    90241 cgggattagg ttatttagta gcttttttag tagctcttgg aggattagct tttaatatag
    90301 gaaatgttgg tggagctgca cttggtatga atgtaatgtt taatatgaat atgacattag
    90361 gaactgtatt aagtggatta atagccatat ttgtatttat gtcaaaaaat tcaaattctc
    90421 tagtcgataa gataactaaa tttttagcat taggaatgat aattatagtt ggatatgtag
    90481 caatatcaaa tcatcctcct gttggagagg cagtatcaag aatggtaaaa ccagaaaatc
    90541 caaaaggact gatattccca ataataactc tacttggagg aagtgttgga ggttatataa
    90601 cttttgctgg aggacataga ttaatagacg gtggaataac aggagaagaa aatataaaag
    90661 aaataactaa atcttctctt ttgggtatat tagttgccac aatgatgaga gttcttttat
    90721 ttttagcaat actggcagtg gtttcaaaag gtcttcaact tgacccagaa aatccagctg
    90781 cttcagcttt taaatttagt gcaggagcaa taggatataa attctttgga cttgtattat
    90841 ggtctgctgc aattacatca gttataggag ctgcttatac atcagtttct ttcttaaaga
    90901 cactaaatcc ttttatagat aaatatgaaa aatattttat aatagcattt atagcaatat
    90961 caacacttat aatggcattt ataggaaaac cagctacttt attaatttta gcaggagctt
    91021 taaatggatt gatacttcca atcacattag gaattatgct tatagcatct aaaagaaaag
    91081 atattgttgg agattacaag catcctacat ggcttttaat atttggatta atagtagttt
    91141 taatatctgc atatacagga ataacttctc ttagcagcct aggtgcttta tttgcttaat
    91201 ttagaagagg tgacatttat ggaaactaga tacttgatat caggggataa ggcagtggtt
    91261 gctgaatttg gaaatgagat atcagaagat ataaacaaaa aagtaatttc atttatgaga
    91321 gcaatagaaa tatcgaatct taaaggtatt gtaacagaaa tggtaccaac atataggtca
    91381 cttatgataa gttataatcc attagaaata gattttgata gtttgattgg gaatttaaaa
    91441 aaaatagaag ataatttgga aagtatagta ttaccaaaac ctaaaataca tgagattcca
    91501 gtatgttatg atgaggtttt tggtatagat attaaaaatg ttgcaagcta taataatctc
    91561 actgtagatg aagttataaa aatacacaca agcagagagt acttgatata tatgctaggg
    91621 tttactcctg gatttccata tctaggtggt atggatgaaa gaatagctac acctagatta
    91681 gaagtgccaa ggactaaaat ttatggtggg agtgttggaa tagcaggttc ccagactggt
    91741 gtatatccta ttgatagtcc tggtggatgg caaataattg gtaggacacc tttaaaatta
    91801 tatgatgaaa atagagaaga acagattttg cttagagctg gagattttat aaaatttgtt
    91861 ccaataacat tagatgaatt tatagaaatc gaaaaaaata acttaagtat ttaaatatcg
    91921 ttatagtaca gggagtggta tatatgggat tcaaagttga attaggaggt ttccaaacat
    91981 taatacaaga cagaggtaga gttggctatg gtcaatatgg tgtatctgga tgtggagcaa
    92041 tggatgagta tgcacataga gtaggaaata tattagtagg aaattctgaa gatgaggctt
    92101 ccttagaagt tttaatgtta ggtcctacaa ttacctttga tgaatatacg caaatagcag
    92161 taactggggg agatttaggg gctaaaataa atggaaaaga aattcaaaac tggaggtcat
    92221 atcaaataaa tccaggtgat gtattatcat ttagaggtgt gaaatcaggt gctagagcct
    92281 atgtgtcaat agctggtgga atagatgttc cacttgcaat gggaagtaag tcaacttata
    92341 caagagctaa aattggtgga tttgaaggta gagcacttaa aaaaggagat tatataaata
    92401 cttttattca ggaaaaagat tttacaataa ataaaaaatt aagttcaaaa tatattccaa
    92461 cttatagttc agaaatcgta ctaagaattg taaaaggtcc tcaatttgat gctttttcta
    92521 atggtgaagt agagaaattt ttatcaaata aatacaaagt tacgaatgaa atagatagaa
    92581 tgggttgtag actagatgga gagagtataa agcaccttaa tggagcagat attatatctg
    92641 atggtatttc ttatggagct atacaagtac ctggtcatgg aaaaccgatt ataatgttat
    92701 cagatagaca gactagtggt ggctatacta agatagggaa cgttataagt gtagatttgt
    92761 ataagttagc acaagcaaag ccaaatgatg tagtaaaatt tgaacttgta gatatatatg
    92821 aagcacatag actattgaga gagcaagaag ataagattca agatatctac aagagtatga
    92881 aaaatataag agttgtaaag gcaaaagtat taaatgatat agcagtttaa ttttaacaaa
    92941 tacaattttt attataattt ataatataac ttacaaatag ctatttacta tttaccataa
    93001 ttaagatggt ttagattagt caaatagcta tttttttagt ttgagtaaat attttaaatt
    93061 taaataaata cttcaaattt aaaataaaag caatatttaa atctattata ttatctacaa
    93121 aaagtaggtg tgtcatattg agtttattta gattttattg gccaaattgg aggtgatata
    93181 actccatatc cacgagctat tgtatcttta cttggattga tgattttatg tggtacatta
    93241 gcttttataa atgttgagtc acctggattt aatctaacta ccttttcacc catacaaata
    93301 tcaaccacac cactcgttac caccataatt tcttctgatg catgatatat ataatctttg
    93361 gcatcctcac tttctggttt aagttcaaac tctacaaata aaattgaagg tgtaaactca
    93421 gttgtaggca ttggagatac tatctcgtaa aacatttcac tctttggaaa tttcatcata
    93481 actctatctt cttttctaat gactaaatca tcagtattat tgtcatccat aaacatatat
    93541 aaaggagtgt ctaaaacttc agcgattttt ctcaatgaag acaaggatgg ttcaatagca
    93601 tctctttcta tttgagagat ataacttata gataaatctg tcaatttgga aacatcactt
    93661 aatgtttttt tcttgctttt tcttatattt ctcatctttt cacctagcat aagaacctcc
    93721 aaataataaa attaatataa aatattcgct taaaacaaag taattatagc acaacataga
    93781 agtagtggca ataagaatac atagtagatt ttgacaatta aaatttaatt aaatccaaat
    93841 aaaagtctat gaaaatgaat tattgttaaa ttaatacaaa gaaaataata ataaaaaaat
    93901 ttaatagaag agtattaatt gaattaagat tatcacatta tattttggaa aagagtaaat
    93961 tttcagtaaa ttatcttgac atatatattg aagtaataat ataatttaaa gtataaaatt
    94021 ttaaaaattg aattataact tcaaaaaata aggagggtaa tatgaagata acagatatca
    94081 aatttgaaaa gcttagaatt aaattaaaaa aacctgtagt agtttcattt ggagtaattg
    94141 agtatggaga aagtgtaatt ttaaaaattg aaactgatga agggtattgt ggatttggcg
    94201 aagcagcacc tcttgcagca gttacaggtg aagttttgga taatgttctt tcagtattgc
    94261 ttatgtttaa aaaagagtta ataggcaaag acccactaga tattgaaacc atacatacca
    94321 tcatggatgg aattattata ggtaatactt ctgcaaaagc agctattgac atagctttat
    94381 atgatattaa aggaaaaatt atgaatgcac ctctttataa agttcttgga ggatttgata
    94441 gtaaagtcca aacggatatt actataagta tagataagcc agaaaaaatg gcagtagaag
    94501 ctttagaaag agtaaaagaa ggttttagga tattgaagct taaagcaggt ataaatcctg
    94561 aagacgatat tgaagctgta aagttaatta gaaaagctgt tggagagagt ataagaatta
    94621 gaattgatgc aaatcaagga tggaacataa atagcagtat aaatactatc aaaaagttag
    94681 aagaatttaa tgttgatgca attgaacaag cacttccaca ttgggattta gatggtactg
    94741 cttacataag aaataaaagt aacacaaaaa ttatgataga tgaatcatta cattcaccaa
    94801 tagatgcaat taaggctata aaaaagaatg cagttgatac atttaatatt aagctgatga
    94861 aatcaagtgg aatatatcct gctataaaaa tcaacaacat agctgaggca agtggagtaa
    94921 attgtatgtt aggatgtatg ctggaaacga gaattggtat aacagcagca gcaaatttaa
    94981 tagcatctaa aaagaacata acagaagctg accttgatag ttttatgttt tgtgaagaat
    95041 tagaaggtat atctggagga tttgtaatgg atggagatat tatgaatctt gtcaataaac
    95101 caggtttagg aatagaagta aacttatgat aaatttggag gttaaatatg aatacacttt
    95161 tttcaaatcc aggtagtata cttgctgtaa tgacatcaat gattgcattg ggtttttact
    95221 tacaaagata caaagccatt aaaagcttag gaccagcact tacaataatc ataatgggaa
    95281 taatactttc aaacttaaaa gtagttccag taagtactga gttatatgga actatttcaa
    95341 catatgctat tccagtttct atgactataa tgttgatgag tgttgactta aaagaaatga
    95401 caaaattatc aagagaacct ttaattgcaa tttttgtagc tgtattaact gtaagtatca
    95461 tggcattttt atttggatta gtatttgcag aaaaaatatc agaaggttgg aaggttgctg
    95521 gaatgtttgt aggtacatac actggtggaa gtgctaatct tacagctatt ggaacaggtc
    95581 ttaatgtaag tagacaaact cttgctgcag caaatgcagc agactatgta attggagtac
    95641 caacattgat atttatgttt gctctaccag caatattaaa aaattcaaag aagtttaaaa
    95701 aactttggcc atatcatgta gaagaatcag aattagagga ttgtcaaaat gaagaattta
    95761 tggagtcaaa agaatggagt attaaagata tagcttggat gttggctata ggttttgttg
    95821 ttacagaggt ttcaacaata cttgctggat atttcaattc aagttttagt agtgcagcaa
    95881 gaatactttt agttacaaca atttcaatta taattgctca attaaagcca gtaaagaaac
    95941 taaagggaaa tttagattta ggattatttg ttgcattatt ctttttatgt acaataggtt
    96001 tttcagtaga tataaaagag tttttaggtt caacttttac tataacactt tactgtttta
    96061 gcataatttt tgcttcattt gttttccatt taggcataac tagactttta aagataaagt
    96121 atcaatatgt aatactttct atagtaggag caattgctga tggtcctact tcagctttag
    96181 tagctgcttc tgcaaagtgg aattcgcttg taagtgtagc agtcgtaatg ggagtaattg
    96241 gtggagtatt aggaaattat gcaggtatat cagtggcata tgcaataaag atgtctctag
    96301 gattataggg gggagtttaa ttgataaaat ttaaattata catatctgga ctatacagtg
    96361 gaaatgtaat ctttgatgga gatttattaa ttgaaaagtt gaatcctttt acaaataaag
    96421 tagaaaattt aaaaccaata agcaaagaag aaaatacata ttatttaaat cttacaaaaa
    96481 tagatttaaa gtctttattt aataactttg atgtatatac taaaagctta gtaaacacag
    96541 ataaagacac agttataaat aacttaggag aaacgcattc taaacttaat gaatatatat
    96601 gggttcaaag aaacaaaaag ttcccactag atataattat tgtagataat aaaatagtag
    96661 gttttatctg tttatccaga gaaacttgta ctatattaat tatggatgga tatgaagagt
    96721 atactgtatt aaaagaatgg gaaaaaactc ataaaaatga agagatatat tctataagat
    96781 ttggtggaaa ttatatgatt aatatgaaag atggtataaa actttctaca gatgtatatc
    96841 tccctgattt tgtagattct accaaaaaag caccaacaat tcttatgaga actccatatg
    96901 gaaaagaaaa tgataaagaa atatattata aatatgtaca aagaggatat gctgttgtaa
    96961 tacaagatgt taggggaaga aatgaatcag aaggtaagtg ggaacctatg attcatgaga
    97021 gggaagatgg agatagtacc ataaattgga tagtatcaca ggaatggtca agtggaatag
    97081 ttggaatgct tggagcatca tatcttggtt atgtccaatg ggcagctgca tcttcaggca
    97141 ataagcatct taaagcttta gttagtatag taacatcagg aagccctttt attgatatac
    97201 caagaaaagg aggagctttt gtatctggta tgcttgcatg ggcatttatg gtatcaagaa
    97261 ataaagttga tagaagcaaa atggtaagag atgattggga tgatgtttta aacatacgac
    97321 caatagaaaa tatacctgtt gaagctcttg gatatagaat tgaatttctg gaagaatggt
    97381 taaagagagt agaaaaagat gagtattggg atttgatgga ttggcattta caaaaagata
    97441 aaataaatgt acctgcattg gttgtatctg ggtggtatga tgataatagt atgggaacta
    97501 cagaggcctt agatgttata aaggactatg aaaaaggaaa gagaaaggct attctaggtc
    97561 catggatgca taattcaaat actttaagag atataaatgg tatttcttta ggaaatagtt
    97621 cattaagata tgatttggat tataattatc tattatggtt tgataaatac ttaaaaggta
    97681 tagaaaataa catagatacg actgctccag tagagtatta ctctgtaggt tctaataagt
    97741 ggaagacaga agaaaattgg ccaataataa ataagataga taaaagtatg tatctaataa
    97801 gtgatggaaa tgctaacaca tctttaggaa atggtagatt agtatttgat aatgatttag
    97861 aagaaaagta tgatagttat atatataatc caaaagaccc atcagtacaa ctaattgata
    97921 tgtcagagaa tgaagttgga gttccaaata actacaaaga tttagaaaaa agaagtgata
    97981 tgttgtgtta tacatcagat gcttttagtg aagaatttac tgtaacaggt gatataaagt
    98041 tagagttttt tgcatcaagt tctgccaaag atactgactg ggttataaaa attatggacg
    98101 tggatttaga tggaaattca attaaattag ctgatggtat acttagtgct agatttagaa
    98161 atagttttta taagtcagag tttatggaag aaggagagat ttataagttt acgattataa
    98221 cttcaaaaat atcaaacacg tttaaagttg gtcataaaat tagactagat ataacgtcta
    98281 gtgctaaaaa ctttattttc caaaatagca acacgacaga gggatataat agtattgaat
    98341 atatagaagc aaagaatacg atttatcatg gaggtaaata tccatctaaa ttgatattgc
    98401 caatagagaa taagtaaatt tatatagatt aaatagtgag gaggtgtctc aaaatgaatt
    98461 ttttagttcg tgagacactt tcttttatac gaaatcaaat atattttcat catttcaaca
    98521 atgaaaaaga ggcttatctc tctgttttga gatagcctcc tataagctaa attgattatt
    98581 ttgtagctgc aacaacgctc atttcaacta acaaatgctc tctagcaagt ctagcttcaa
    98641 cacaagctct agcaggttca aatccttttt caacccaagc atcccaaaca gagttcatag
    98701 cttcaaagtc tttcatatct cttaaataaa tagtaacaga tagcaaatgt tgcttatctg
    98761 aaccatattt gtttaataaa tcttctattt tagctaaaac ttcagttgtt tgttcaatta
    98821 ctcctccttc agcatgagtt tgtccacata aataaactgt attgttatga actacagctc
    98881 tactcattct tccagttcct tcatatctct ttatttccat attttaaata cctccatagt
    98941 taaaaaatct attaaaaatc taaataataa attaaaaaaa gtctatacta tataaaatta
    99001 tattatatat tctgataata atccataaaa acatataact ttttagctat aattattatt
    99061 gttattaatt gaaaagattt attagttact tgacatagtt tacactttta attatagtat
    99121 aaattggaat atttagataa ttattattta atgtataagc taagttttta attaatatgg
    99181 ctttatacat ttatatagaa aagaggtacg tatgagtagc acaatcaaat caaatcgaat
    99241 aaaaggtata atgtttataa tagcatcagc gcttggcttt gcaatgatgt ctgcattcgt
    99301 aaagctagct ggagatttac caagttttca aaaagtgttc tttagaaatc tggtatcagc
    99361 tataatagct ttttggctta tcataaaaca taaaggaagt ctaactggta aaaaagaaaa
    99421 tttaaaagta cttttatata ggtcaatatt tggaactcta ggagttatat ttaactacta
    99481 tgcgattgac aagttgatgc tttcagatgc taatatgcta aataaaatga gtcccttcct
    99541 tgtagtaata ttttgtgcaa ttgctctaaa agaaaaaata aatgtaaagc agataggagc
    99601 tattataatt gcatttatag gagctttatt cataataaaa ccaacattta gtgtagaagt
    99661 aattccatat cttggaggaa ttgcaggagc tgtatttgca gcaatggcat atacttgttt
    99721 aagagttctt ggagatagag aagattacta tacaattgta tttttctttt cagttttttc
    99781 attagttact gtagggccaa ttgcttttgc agtatatgaa ccaatgaccc ttatgcaact
    99841 tatatatcta ttactaggtg gagtatttgc aagtctaggt caatttggaa taactctagc
    99901 atataaatat gcacctgcta aggaaatctc tatatttgac tatagtaata taatcttttc
    99961 agcaatttta agtatattct tattcaatgt ctatccagat atgttaagtg ttgttggata
   100021 tttaatagta ttttcggcag cattttatat gtttttatac aataagaagt tagataaatt
   100081 agacaaagaa aagaagaagt aaactagata aaagtgtttt tataatttgt attgaatatt
   100141 taagtctttg tattaaaatt aaagaaaatt taattaaaaa tgtttggtat attaacttat
   100201 aacagcagtt aaaattgaaa aattataact gctgtttctt ttattaaaaa tatccaaatg
   100261 tctgtaaaaa tagactataa tagagtagta taaataatat aaaggggata aattaaagta
   100321 tggaaaaagt gaaagttgct gtgattggag caggtaatag aggaacgtat gcatatgctc
   100381 catatattta tgaaaattct gatgtatgtg aaatagttgc tgtagcagaa cctaaaaaag
   100441 gaagacgaga actatttaca caaaaatata acctagatag taaaaatgta tttgaaactt
   100501 tagaagactt ttttaaacat gacaagatgg cagatgcagt aataatagct acaaatgatg
   100561 atagacatta tgatgtagca aaactagctc ttgaaaaagg ttatcatgta ctattagaaa
   100621 agccaatgtc taatagttta gatggtctgg tacatataga tgacttgtgt gataagtata
   100681 aagataagat ttttatgatt tgccatgtac tgagatattc tccattttat aataaattaa
   100741 aagaaattgt agaaagcaaa aaattaggag agctagttag tatacaatat aatgaaaata
   100801 taggatattg gcattttgca catagcttta ctagagggaa ttggagaaat agcaatgaaa
   100861 ccagcccttt aattttagca aagagttgtc atgacatgga tattttgtta tatttagtag
   100921 gaagtagatg caaaaaaata tctgcatttg gaagcttaaa gcatcttaat aaccaaaatg
   100981 ctagtggaga gatggcacaa aattgtcttc agtgtttagt tgaaaaaaaa tgtccatatt
   101041 cagcaaagag aatttattta gaaaaagata gaagtataaa tagagctgtt cacataaatc
   101101 caactgaaga gaatctatta aatatactta agacaagtcc atatggaaga tgtgtttaca
   101161 gatgtgataa taatgttgta gacaatatgg taaatatact acagtttgaa aatggagtga
   101221 cggctacttt taatttatgt gcatttacta aagaaaatgg aagaactata aagttaatgt
   101281 ttagccatgg tgaagttggt ggggatttaa ataaaaatga gataagaatt aaagaatttg
   101341 gaaaaaacga agaaatagtt atgaatccat caaatcaaca gaatatggta gaggaatatg
   101401 atagaaatct tatagctgaa tttattaaat tagtttcaaa taaagaacta gaaaagggta
   101461 gagtagcagc aaaagaagct atacaaagtc atgtaatggc atttgcagca gaatattcta
   101521 gggtcagtga tgaagtagtg tatatagaag aattttttga tagtgctaag caaatgacta
   101581 aggagataga agaaactata ttttaattaa taaaaattta ttaaataaaa taaagataga
   101641 ttaaataata gaaatacgaa aatatgtgtt ctattaagga atctatcttt tttattaagg
   101701 ttttttctta tccctatcaa aaaaatccat acattctgat aaaagataag aaagtaaagc
   101761 gaataagatt tctgtactta aaggaatcgt tactgaatcc ataaaggtat caattatgtt
   101821 catagctaga aaagttagta taaaatcaat tataaattcg caaagtttat atattgagta
   101881 tggtaatttg tttacatatc tgaatatatc taaaatagta gtgcatagaa aatcaattgg
   101941 agtggttata caaaaatata ttaaaaagaa aattaataca gctccaagag atttatattc
   102001 aaatcctaag aatgataaga agccaattcc tataaccgtg aaaatacaaa aagttatacc
   102061 aaaaaaaaca gcaaaaaata aaaatacaga aataaattcg cctaaaggaa tccttctttt
   102121 attacttatc ttaatcaact ccttaattta tgatatgaaa tttatataaa taataacatt
   102181 cttaaaaatt cataatagtc ctctgtttca aatagtactg tttgagaatc tatttttttc
   102241 atatttggat aaaaagaggc cttaaaagct ttataatgtt ctctaaattt tatttctatc
   102301 ttaaatttat ctggcaattt tattaagtgc ctagataaat ctccagataa agcttttttg
   102361 acaccttttt caattttttt tagtgcaagg tttggatgga ttgaaattga accatttcca
   102421 attccttttg acacaggaac agtgactata tttggattta gtttttttgc actctcacaa
   102481 agcatttcat ctccacttaa aaatgctaca ggaacattat aatatgcagc aatataagca
   102541 tttatagtaa attcagatgc tatttcatca tttattttaa aatagtcata atcaatatcc
   102601 atagtatggg aaagtggatt accattacaa gtagctccag agtgatagcc agtgaatata
   102661 catgcatcaa agctttcatc aattccagcc atcataacta gtgggtcttt ggtccatcct
   102721 ctaagtattt tgacgttttc aggtaaaata tttggattaa tatttctacc actgtcatgt
   102781 gcatctttaa caagtatttc atgtacacca gattgagtag ctccatcaca tgctgctgtt
   102841 atctctttac tcatttgtgt tctatagtgt tgcgaaaatt cacattcaag ttttgtttca
   102901 tcccaattta caataccaca agtaccttct atatcagcac ttaaatacaa tttcataata
   102961 tataccccct tatgtttatt attgatgata ataacagata acagaaaata cataatcaat
   103021 aaagggcata aaaatattat gtcttactat taactattat taaatctgta actgaaaaat
   103081 aactaaattg gtataaaaaa atataacact atgtgtcatt tatttatata gttttttata
   103141 tttgatgttt atataaaatt gtaacatata agtggttaca tttactagtt taacatagtt
   103201 aaaatagtta ggtattattt ttaagttaaa ttgattatta taaaatcgca gaataaaaga
   103261 aaaacttaat ttattaaaat gcatgaaatg ttttttcctc aacataatgc taaattaaac
   103321 tcaaaaagaa ataatagaaa aatcttatgt agcttagaaa gaatgtgaat gatttaaggg
   103381 aaaaatagaa atttattata taatattagg ctgtattata taatacagcc taatattata
   103441 tgtatatgtg acataaaatc ttggtaagtg taaataaaat aaatgtggaa aacaagttaa
   103501 tgaaatcaag aaaaaagtaa tttaaaattc aatttcatct tcccaattaa attctcctga
   103561 tttttctaca ctcttaggcc agtgactaca ccatttagga acggacggat tttcaaccct
   103621 atcaacgctt ggagtatatg gctttaagtc aataacagga ctattatcat tagcatcaat
   103681 atatggtatt tttattatgc cattttcatg gtcgatattg ataatttgta cagcagtcaa
   103741 tgctattgga ttgggtctta taggtgacct tgttgcaaat attcctataa cgtctggtcc
   103801 acttttataa ggttttgggg tttctaaaat acttcttagt tcaggattat caaacccatc
   103861 agcccaccaa aatacattta aatgactgaa atcgtcgagt tcatttaatg caggtacata
   103921 ctttttgtct aatttaataa agacctcttc gccttgaata catattttac ctataggatt
   103981 tattaatatt tctttcataa tattacctcc aactatttaa tttatcattt gtaattttag
   104041 ggtataacat gacatcatgt gagggtcaat ataaaataat aaataaaaat attaatagtt
   104101 agaatgataa tacatttttt acatggagca tgacaccagt aataaggcaa tcttcgtcaa
   104161 tatcaaaagt agaggtatgc aaagaggaag taatgttttt ttcacgattt gcacaaccaa
   104221 ggtggtaaaa agctccttca cagtgtctta gaaaatacga aaagtcttca gccccaagag
   104281 tgggcgagtc tttaaggata atattttctt caccaaacaa ttctacagca ttttgtttga
   104341 cgtaatctac tagatggttt gaattgataa gagctggata accttcctca atttcaacag
   104401 aaatacttcc tccaaatgtt ttacaagtaa aatcgcaaat ttctctaatt cgtttttttg
   104461 aaaactctct agtttcagga gtcaaggttc tcaaagtacc ccttataacc actttgtcac
   104521 aaactatatt ttccttgatt ccaccttcaa tttttcctag agaaataacc acagaatcag
   104581 ttggatttgt gtttcgacta acgattgtct gtagagctgt aataatatga gcagatataa
   104641 caatagcatc aataccttga tgtggataag ctccatgaca ttttgaacca tgtacagtta
   104701 attgaagtgt atcggtggaa gcatttagag tgttgtattt taattcaatt agatttttgt
   104761 tgatattggg atttacatga agtccaaata tatattttac atttgggttt tcaagacatc
   104821 catcttctat cataagttga gccccaccaa tagtttcctc ggcaggttga aaaaagaatt
   104881 ttacatttac atttaagtaa tcctttaatt taaatagtat attacaagta cccagtaaaa
   104941 tagcagtgtg tgcatcatga ccacatgcat gcattttgcc aatattaata gatttataag
   105001 aataattaag ttcttctgtt ataggtaagg catctatatc agctcttata gcaactgttt
   105061 caaagtttgg actcacgtta atgtatgcag ttatccctgt atgattctta tattcaatat
   105121 aatttatacc tatttcattt aagtatttaa taattttttt cttagtttga aattcttcta
   105181 atccaagttc tggagtctta tgtaaatctc ttcttatatt tataacccaa tcatttatct
   105241 catgacaaag agtttttata ttaagcataa aacacatcct aactatatta aaaatttatt
   105301 tttcttcatt aattatatta ttttatgtaa atcattatta tgtatcaagt acaaataaaa
   105361 tatcttataa ttatattaga gatatttagt atggagaaga atatatcatt ttataagaag
   105421 aggtgtttaa atgttaggaa taattgcgcc atctgggcca ttaagaaata caagtttgga
   105481 ggaaataaag tttaatttag aaagttatgg ttacgaagtt aagttttctg aaagttgtag
   105541 tttaaattat aaaggttatt tagctggtaa tgatgatatt agagcaaggg atatagaaga
   105601 tatgttttta gataaagatg tagatataat tatgtgctta agaggaggtt atggaacaac
   105661 aagaatattg gataaaataa attatgatat aataaagcaa aatccaaaac catttatagg
   105721 tttttctgat ataacaggtt taaatttagc tttctataaa aattgtggtc ttttaccata
   105781 tcatggaata atggcagcaa atgtaggtaa atgggataaa tttacctata aatcattggt
   105841 aaatgcttta gaatttaaag atgaattata tttagaaaat ccaaaagaag aaaagattta
   105901 tactgtatgt gaaggtaaag cagagggaat aataatggga ggaaatttat ccttaataat
   105961 tgccacaatg ggaacaaaat atgaaataga ttcaaaagat aaaattttgt ttattgagga
   106021 aattggagaa cctcaatata aattggatag aatgttaaca caactatatt cttcaggaaa
   106081 acttgaggaa tgtaatggta taatttttgg agattttaag gattgtattg aagaaaatga
   106141 tttgatggaa ttactaatag aatttgcaaa taaggtcaat aaaccttcta tatataatct
   106201 tcagtcagga cattgtatcc caatgataac tattcctttg ggcagaatgt gcgaattaga
   106261 tgctacagaa aaaatcgtta aattaaaaaa atagtgtgta tataaatata atagaaatat
   106321 ggtataatct tatacaagta aaaatttagc taggaggatg aaaaatgtct gatgatagaa
   106381 taatagactt taacgaacta aagaacaaag ttaaagattc tgatgtagat aaatttgagc
   106441 aatacatata taacttatat ttttctgtta tggatggaaa gatgtctatg gctgagtttt
   106501 caagaaaaat attcgattat atgagagata acaacatatc tcaagaaaaa tttatgaaaa
   106561 tacaaaagca atttatggag agatatggta tggacactga agaagtagaa aaacaactta
   106621 gaaactttgg aatcgaccct tctacagcag gttttatgag taataatact tccagcaaag
   106681 tatctacaga agatttagag tcatttaaga agagtgcagg attttatgag aaatatggag
   106741 aaaaaatcca accaaagagt tgtataacaa catttataaa aaatgactta aatgatatta
   106801 atgtaataat cgaccaagaa aagataatgc tttgtagtga tagaaaaata aatcttatgg
   106861 attcagaact aaatgagttt ttattagaat ataagaatat gtttaataaa aaaataaagg
   106921 tagtaatgtg cgaaactacg aataagtatg attattaaaa aatgaattta aatactgaag
   106981 tagtatcaat taattgtact acttaaaaat aaaaatcgca atttattatt ccttataaat
   107041 ttgtataagg aatatctaaa ctgcgatttt ttatattgtg aagattagta ataatagata
   107101 gtgttttaaa ttgtaatctt ctcactaaaa ctgtgttttt ctattagaaa ttttattaaa
   107161 aataaatatc tgataattgt attatatggg atgtaaagta ttagaagctt aacgaatctc
   107221 ttttaataca ttaactccat tttgaatcat actgttgaaa aatactaagt ttaaaatctc
   107281 agcagggtga acgttaggaa tatcataagt atctactaaa ttcataggta caactatatt
   107341 tttttcaata ttatgttgat taaaatatga ttttagagtt attgcaaatt gatatataca
   107401 tatatctgtg caatcgccaa ctataattat attatctata ttatcaaaat ccaaattttc
   107461 taatgcaaaa aaaccattag tagaattttt aggaagaatt tgtaggtttt ctatcgactt
   107521 aagttcatca accaattcac tttctacatc attttccaaa cagtgaacag gataactcaa
   107581 aagttctatt gatttaggag tatgagaatc agtaaatgct attactctat ttaatttgtt
   107641 tgatattttt tttgtaaaca tttcaattgg ctttattaaa gactctactc taggagagta
   107701 taatgcacct tgtcttgcaa agccattatt aacatcaatt ataaataaag cagttttact
   107761 caaatcataa ttttctattt tttctattgg tagattatct aaattactct ttaaagcttc
   107821 aagttcattt aataagttat ccatagttat acctccaaga taaatttaat aaaattgtac
   107881 atattaatta tataaaagtc aaggagtaca aactattgta taattagctg tattgttttg
   107941 agtgtaaaag atttgaagca atatctggat agttagtaaa aataccatct acattgagtt
   108001 ttaggcagtg tagtatatca tcctcttcat ttacagtata tacattgaca ccaagtagat
   108061 ttttgtgaca aagttcaatt agagattcat ttactaaaac tagaggtgga tgaaggtaac
   108121 tattacccag aaatttagca aaattgacta cattgtttat aggtaaataa cacaataatc
   108181 ctgtttttac actagggtct aatttatgaa agttttttaa gctattgctg ttgaaactag
   108241 atataagaac tctatttttc atattatact ttaaaataag ctctaaaacg tctttttcta
   108301 tattgggata gtttattttg tcagttttta gttctatatt taaaataagg tctgtaggtg
   108361 aaattagaat taatacttct tctaaagttg gaattttaca ttctttattg ctttgatatc
   108421 cttcaaaaga tgagtttaga gtttttaatt ttcttaaagt aaagtctttt acaaaaccat
   108481 gtccattaaa agttctatca accttttcat catgaatgac tacaattttt ccatccttag
   108541 ttctgtggac atcaagttct attccatata tatccatatc caaacatttt ttaaaagcta
   108601 gaatagtatt ttctggatac tttccactaa accccctatg agcataaata ttcatttata
   108661 tggttccctc ctataagtat aacttatctt ataaaaattt aattaatata atatatcata
   108721 ttccaaaagg tattgttata tattagttaa ataactattt gtaatttata tattatataa
   108781 atgtagaaaa ataaaatcat atatgtgtta taatatattt taaacattgt aaatattacg
   108841 aatttagtag tcataataag tgtaatttta tgcaagctca tgtttttaga gcttgcatat
   108901 gtattattaa tatatttata tattgtgaaa ataaaattcc aaaagaattt tttctataga
   108961 cttagtagta agggggaatt ttgatatgta tgaagttaat ttagaacgag ctatgaatta
   109021 ttggatggat ttgttagatg attatacgaa tatagcaaaa attccaaatg atttttttta
   109081 taaagattgt tctgatgaag tagtcgatga ggtttttaag atgaatattg agaaacatga
   109141 aaggttaatt caatattcta aagtgaacaa tattagcata gactctatca tagaaactat
   109201 atatggcctt atacttcaaa agtatatata tgaagatgat gtagtttttg gtaaaacaat
   109261 gaatataatt ccaataagag taagagttag acaaagtgaa aaatttatag atgttgtaag
   109321 gaagctaaaa aggcagtgga gcaggtcttt agagtatgga tactatttgt tatcagatat
   109381 agagaataaa aatcatctaa atactaagct tataaacaca atatttatag ctaaaagttt
   109441 tgatttatca tatgattatg acatagaaaa aaaaggatat gatttatctg taatagtata
   109501 tactaagagg gcacttaaaa taaaaataaa gtataaacca tctatatata aaagagaaac
   109561 tattagaaga attttaaatc aatttgatta tataatagag caaataatag aagataatga
   109621 tattttaata gaagatttag aatttgtatg taaggaagaa gaaaaagtat tattggaaga
   109681 ctttaataat aatcaatatg aagtacccta tgataaaagt tatgttgatt tatttaggga
   109741 gcaagttaag gtaacaccta gtaatatagc tgctagggat gaaaatagaa agttaacata
   109801 taaagaattg gatgaagtaa ctgataaact tgcaggttat ttaaatcata taggagtgga
   109861 aagtgaagac atagtagctg taatgttacc aagagatatt aacataatta ttacagcaat
   109921 agggattatg aaatcagggg gagcattttt tccaatagac acaagtaatc cagaagaaag
   109981 attgaattac cttcttgaag atagtaatgc aaaagtagtg ataactacag atgaactcaa
   110041 aagtaaggtt gtaaatgaga ataccatagt actcgatata aatgatgaag aaatgtttaa
   110101 gcttggatat gaattaactg aaaaaataac atcatcaaat tgtgcatata cgatatctac
   110161 ttcagggtca actggtaggc caaagaccat agctatagaa cataagagtt tagtaaatat
   110221 gtgttattat agcgtaaaat ctataagcgc tacagaaaat gatatatgtg gtatatactt
   110281 aagtttcagt tttgatgctg taatgaaaca actattccct tatttgcttg taggtgcatc
   110341 aatagatatt atgcctgaag aagctaaatt tgatgaatat acagtaaatg aatactgtga
   110401 ggaaaatgac ataactatac tagcattgcc aacagcattt gcaaggttat ttatacaaaa
   110461 ttgcaataat aattcactta gagttgtaca gaccggagga gaaagattaa aaggatatag
   110521 aaagcgtaat tatgaactat ataatgagta tggaccaacc gaatttactg ttgtatcgac
   110581 ttcttttcat gtggacagag aatatggaaa aataccaata ggaaaaccta tatttaatac
   110641 ttatgcatat gtattagata aaaagaacaa actatgtcca attggagcac caggagagct
   110701 atgtctatca ggcattcaaa tatcaagagg atatttaaat aaaaaagggc taacagagca
   110761 agtatttgta gagaatcctt acaaaacttg tgaacataat aagttaatgt atagaactgg
   110821 tgatttagta agatggttag atgatggaaa tttagattat attggaagga tggacaatca
   110881 agtaaaaatt gatgagttta ggatagagct atatgagatt gaaaatataa taaataatat
   110941 tacagaaatt aaaagtgttg tttgtatatc gagaacaaat gatgatggag atatgtatat
   111001 atgtgcatat tatgtaattg atgaggaaga tagtggtaag ataaatgaaa gaactattag
   111061 agaatattta aatgagcatc tacctccata tatgattcca acaataataa tgaggataga
   111121 taagatacca gttacaccaa tcggaaaagt aaataaaaga gcattaccag aataattttt
   111181 tattatgata ggtgtcataa agtgatttca gacatttctt tatgacactt atttttataa
   111241 aagaatcaat ttgcataaaa acaagaattt tctgtatata tttactatgg tgaaaattta
   111301 tttataagaa tgattattgt attttttata cttttccgtg ttttaaagca ttttttttac
   111361 aaaattaatt ttacattaaa aaaatttttt attttatatc ttaatagttt ttagtagaat
   111421 tgaaaaataa aaagaaaatt agcataaaaa tatctaaaag tagaaattaa taatataggg
   111481 ttaaatttta gtagttttga ctcgctattt gtaaaataat aaaaagttaa gttttatatg
   111541 tatatatgtt ataatatata caaattgaaa aggggtgaaa attttatgaa caaaaaatta
   111601 cctaagggtg cttatggtga ggttagtgga aaagattacg ttccatatat cacagataag
   111661 tccagaaccg gtggaaatgt agctgtactg attatcggta ttattttagc tgccattttt
   111721 gccgcatcta caacttactc tggaatgaaa gccggtctta cagttgccgc aggtattcca
   111781 ggagctataa taggttctgc ttttgttgga gcatttgctc gttcaaaggg tattcttggt
   111841 aaaaacttaa tccaaggtat gtcaagtggt ggagaatctg ttgcaagtgg atttattttc
   111901 gtattaccag cagttatatt aattggaagc caaattacat tctttgaagg cttagctgtt
   111961 ggagttggtg gagttttatt tggtatagga attgctgcta tagttcacaa ctatctaata
   112021 gttgaagaac atggtaaact tatgtaccca gaatcaatgg ctatatctga aacacttgtt
   112081 gcttcagagg ctggtggaga ttcaattaag tacatgggaa ttggatttgt aataagtgga
   112141 tttattactg tattaactgg ttcattctta aatgtagcaa acaatgtaat gagtcttgta
   112201 ggaagcaaat tctacaaatg gaaatttgat attgaagtaa atcctctact tttaggaatt
   112261 ggatttatag tagggcttga agtttcttta acaatgtttg caggaagtat tttatcaaac
   112321 tttggtatag cacctttaat aggatacttt acagatatgg ctaaagatgg agctatggta
   112381 tggaataatc ctgcaatgcc tcttaaccaa atggatgttg gagcaatatc tagtagttat
   112441 gtaaaatata taggtgctgg tatgatgctt tgtggaggta ttattggtgc aataaaactt
   112501 ataccaacta taatcgcttc tataaaagaa acacttaaag ctaaatcaag tgctggagaa
   112561 ggagaagaag gttcatctat acaaatgata cttttattag gtggagtagt tattggattt
   112621 ttagcagcat tcttaatttc tggtaacatt gttatggcaa ttattggagc tatcatatct
   112681 cttttattat ctttattatt tgtcatagta gctggtcgtt taacaggaac aatcggaaca
   112741 tcaaatcttc cagtttctgg tatgactata gcttctctag ttattgtaac attagtgttt
   112801 gttataatgg gatggactga tttagaagct aataaatcat tacttttatt tggttcattt
   112861 atagttgttg ctattgctat agctggaggt tatactcaat ctcaaaaagt aacttatatt
   112921 attggtggta gcaaaaacga aatgcaacgt tactttacaa ttgcaagtat agttggtgtt
   112981 atagttgttg taggagtaat tttattactt tctgaccaac ttagagcaac tggtgataat
   113041 gtacaatttg cattaccaca agcaaactta atgtcaacat taacttctgg tattatgtca
   113101 ggtagtttac cttgggttat gattattgtt ggagtattta tggcaatcgt tctatatgca
   113161 ttaaatttac caataatgac tatagctata ggattctatt taccaattgc aacaacttct
   113221 ataatattag ttggagcatt aattcgttta tttgttgaat tagtatctaa aactgaaaaa
   113281 gaaaaagaag ttaaagtttc taatggtata agtttatctt ctggtcttgt tgctggtggt
   113341 tctatcattg gtttaatagg tataatatta caagtaactg gagttgtaac tccaaaggta
   113401 ccaagtggat ttgctgcaac aaattcaatg gcaattgctt tattggtagt tttagttgtg
   113461 cttacagcat tacctattgt tttatctaaa gtaaaaaata atgagcaaga gtaatgatgt
   113521 tttagatatt gtatttaaaa ttactgatgg acttgaatat gaagtagctg aaaatagtgt
   113581 tgttactata cttgaaaaac aggaccataa aattcaaaag ttttttagaa agttaaaagc
   113641 tagaatacct aaatacaaaa aaatagaact agatgaatat tccagttttg tttttttaca
   113701 aattgatggt caaaggactg ttagagaaat aggcaagaac ctagaagcta aatatggaga
   113761 agaatctcat ccactttatg aaaggttgtt agtattttta aatcatattg aagttaattg
   113821 tcactatatt gaaagactgg atatatagat ataataagaa ttattataga tatattagag
   113881 catataaatt agaaggtaat tatgaaagag gctgtctcaa aatagagata agcctctttt
   113941 gtattgttga aatgatgaaa acatatttga tttctcataa aaaagagtgt ctcataaaac
   114001 taaaaagttc attttgagac acttccttta aaatgtttat aaagtacaga tttaaagtaa
   114061 aacttattaa acttaagatt attttaatat cacttattat tagctatttc atcagctaga
   114121 ttatttaaat attcccatct ttcatatttg tattcaagtt ctttttctag tttagatttc
   114181 tcatctaaaa tttcttgaag tttagtaaaa tcagttgaaa attttgcagt actttcatca
   114241 agtgttgcaa ttttagattc gagtttttct atatcagagt caatattttc aaactctctt
   114301 tgttcattat atgagaactt aagcttttta tcatttttag gtttttcttt ttttagggta
   114361 gtagagtcat cttttttaac tgattccttt ttagattctt caaattcaat tccttgaatc
   114421 tctctataaa taagataatc actgtaatta cctgtataga tatgaatttt tccattacct
   114481 tcatatgcaa atattttatt acaaattcta tctaagaaat atctatcatg tgatactgta
   114541 actactacac ctttaaattc gtctaggtat tcttctaata ttttaagcgt ttcaatatct
   114601 aaatcatttg taggttcatc taaaagaagc acattaggag ctgtcataag gattttaaga
   114661 agatgtagtc ttcttctttc accaccagat aatttaccta tcaaagtata ttgcatagta
   114721 ccattaaaaa ggaatctttc acacatttga gaagctgtaa tcctagtacc atctgaagtt
   114781 tctatatagt cactagcttc ttttacatag tctatagccc tcatatcaat attcatatga
   114841 gagtcgtctt gagaaaaaca acctatttta accgtttctc caattgaaat atatccacta
   114901 tcaggctcta tttctccatt aagtatattt ataagggtag atttacccat accatttttg
   114961 cctattatac caattctatc tgtacgagtt aaagtgtatt ctaaattatc tataacagta
   115021 ttttcttcaa atgatttaga tatattgtgt atttctatta ttttatttcc aagtctactt
   115081 gatgcaacag atatatcgag attttcatca ggtttaaaag aatatctatt tataagttca
   115141 tcaaatcttt gtaaacgagc tttttgttta gtgctacgag cctgagctcc tcgtcttacc
   115201 cacgcaagct ctgttcttat taaattttgt cttttatctt caatacttgc ttctagcgaa
   115261 agtctttcca ttttcttttc caaaaatatt gaataattcc catcataact gaataatcta
   115321 cccttgtcca gttcaataat tctatttgta acacggtcta aaaagtatct atcatgagtt
   115381 atcataagca atgaaccttt tctggaatta agatattcct caagccaatc tatagtatca
   115441 ttgtctagat ggtttgtagg ctcatctagt atcaaaaact cacaaggtgt aataagggct
   115501 gatgccagag agactctctt tctttgccca ccagaaagtt ctgctatttt ttgattaaag
   115561 tcatttatac caagctttgt aagtactgac ttagcttcac tttctaaatc ccaaagattt
   115621 aaggcatcta ttttttcgtg tactgataat aattttttat ttaattcctc tgtaaagttt
   115681 gaattaagtt tttctaggat ttcttgatat tcaccaagta gctttaattc ttcagaagtt
   115741 ccattaaata cttgttcaag tacagttgaa ttttcattgt aagttggatt ttgaggtaga
   115801 tattctatcc taataccatt agtttttgtt atattaccag tctcactttc ttcaactcct
   115861 gcaataattt tgagtaaggt agatttacca gtaccattta caccaataag tcctattttt
   115921 tccccttcat ttattccaag agatatattt tctagtaatt ttttttcaga atagctttta
   115981 cttatatttt ccaatgtcat taaattcata taattcacct ttatttctaa tctattattt
   116041 ttcaaaatgt tgataatctg ggtttttcca atagccaccc caactccaac ctctgcttac
   116101 aaaagcatta taacaatcat cacctttttt tatcattcca aattttgtgc tagacctatc
   116161 agcataaact gtacttactt taggtgtaac atcatttcca gaaacttgag gattctgtaa
   116221 tgggtttata tctatagcac gtcctttacc atgatttgaa actacatttg taccagctat
   116281 agttctataa caaaatgatg aggtattatt atcagacata gatttttcat ctacagcatc
   116341 atagtcatct attaacttaa ttttttcaat tggatatttt ttttcgtata attccttaaa
   116401 aatatccact acttctggag ctagttcact gtttactatc atttctcctt gatgagtttt
   116461 ttcatcaaat ccataatatg taagttttaa ataagataga ctatcaaagc ttataggttc
   116521 atcagtaggc atagatttac caatcatttt attttttata ttatctggta ttgaagaata
   116581 tgaaaaagta ggtttgatat tattatcttc ctgctttttg gtagagcttt gattattttt
   116641 agaatcatct gttgtattat ttttattttg catagtttct tgactcttta tattaccttt
   116701 tttgttggga ttagagaaca gtatctcata tatagataat aaagcaagaa ataatacagt
   116761 tattacaatc gttaatttta atttattaat ttttcttcgt tttgactttt tactcatatt
   116821 atcccccagt attagattca tataaactat atatattata cctcataaaa ataaactagg
   116881 ctaacaatat ttagttaacc tagaacattt catttatagt ttctccaatt atttttattc
   116941 caatttcaat gtcttcaaaa gacaacctag aaaatccgag ccttaaagta tcaaaaccag
   117001 agttatctgt aaaaaataaa tctccaggca taaatataac atttttttca taacattttt
   117061 ctaataaaac tctagtatct atatttttta gttttataaa tatatgcaaa ccaccatcac
   117121 ccaagatata ttctgttttt atatattttt ttatacactt atatgcaaag ttaaatttgt
   117181 ctccatagaa tttacgtatt tttttaatgt atttttcaaa acctccatta cttaaataat
   117241 caaataaaat tccttggtct aaaaaggata catgtatgtt tctgcacctt tttacacttt
   117301 ctagcttatt gattactttt ttatctgcaa atatccatcc aattctcatt ccaggaaata
   117361 aaatttttga aaaactacca atatatacga ccccattatt catattatct agggaacaga
   117421 taggaaatat atgagaacta ttgtagagta attcttcatt aaatccatct tctataattg
   117481 ctatattgta ttttttcata agattataga atttgtacct attttcagga gtcattacaa
   117541 ttcctgtagg attgtgataa gagggtgtaa tgtatgcaaa ctttatttta tttttatact
   117601 taactaaatt gtcttctagc atattgaagt ccaaaccatc ttcatttata tctacaccta
   117661 agatattgag gttatgagat ttcataattt ttatagcagt attatgagta ggattttcac
   117721 atattatgta gtctttttct tgggtaaaag atgacataat aatatcaaag ccttctgtga
   117781 atccatttgt tattagtata tctttattac ttatatcagc acccttgttt gtcatatatt
   117841 ctagtaaata gtcaataagt ggcttataac cttgtgcata tccatagttg agtaatttat
   117901 gtccttctag tgaaattcta tttaaaaagg atttttttaa ttcttccatg tcgaataaat
   117961 ctccatctgg agaaatactt ttaaaggaaa tcaggtcaga gctccaagga atttcacttt
   118021 ttataatgtc caattcattg gcttttttag agtatgtatt ctctaaacaa tcccagttta
   118081 atgaccatgt agtatttgaa gacttattct ttgatttaac aaatgtacct tttcctgaaa
   118141 tagagtagat taatccttct gattttaatt cttcataagt taaaactaca gaatttcggc
   118201 taacttgtaa aagctgacta agctcccttg tagaagggag cttactattg tctggaatta
   118261 gtccttttga tatcatatca cttatataat ttttaagttg tatataaatt ggttcattat
   118321 catttaattt tagatttgaa aatatcaaat taccacctca aattatttca tctaatttaa
   118381 agagtattct ataagtttat ctaatagttc actgtactta atacctctag cagcagcact
   118441 tctaggaatt aaactagttt gagtcattcc aggaagagta tttagttcaa gaacatatgg
   118501 aataccttca cttataatca tatcaactct tacatatgct ttgcaattaa aaattttcca
   118561 acaagtctca gaaatttcgt ttactctttt ttgaagttct tcatctaaat aaacaacttc
   118621 ttcctttgca cctttttcaa ctgagtattt agcttcataa tcaaagaatc ctgaatcaga
   118681 ttttatagat attgtaggga acacttctcc atttaatatg aatgaagtat attctccacc
   118741 tggtatatat ttttcaatca ttacaaattc atcaacttcc agaccttttc taactgcttc
   118801 ttcaacttca tccttagaat gaataaagaa tgtggctaca cttgaacctc ctgagtttgg
   118861 ttttataaat actggataac ctatattatc tatttcatca tagtctattt catcaactga
   118921 ttttactaaa acccatggag cagtaggtag gtttgaatct ctaagcattt ttttagttat
   118981 atttttatcc atacacatcc cactgcaaag aggtccacat ccagagtata gtatatccat
   119041 agtctcaagt attgattgta tacatccatc ttcaccaaat tttccatgta aagcaagtat
   119101 tgcaaaatct atatcttctg gtatctttgt aaatatatct tttttatcat ctattattac
   119161 ttttacaact tcatatttat ttttatcaag gttattatat atctcttttc ctgaatttaa
   119221 agaaacttct ctctctgatg atattccacc cattataact gctattttca tattatacac
   119281 tcctatttta atttttatta ttttaaagta aactttttat ttacatactt aattatatga
   119341 attaacagtt gaggatgaaa gtaccactat atacgaagtt tatattatgt gtggttttag
   119401 aataataatc tagtttaaag atatgtttaa atgatttttt aactttattt atgttattat
   119461 ttttgctaaa attattgtta tgaacttaag actagtctta atggctataa atcaaggagt
   119521 gataaatttt gaaagctgaa ataataagtg taggaacaga aatattattg ggagatatag
   119581 taaatacaaa ttctcaattt ttagctaaag aacttgcatc attgggaata gaagtatacc
   119641 atcagagtac tgttggagat aacaaacaaa gacttttaga atgttttgat gaaagcttaa
   119701 agagaagtga ttttgtaatt actacaggtg gtcttgggcc aactggtgat gatatgacaa
   119761 aagaaactgc tgcagaatac tttggtcaga aattagaact acataaacct tcactagagg
   119821 ttttggaatc tttctttgtt aaaacaggga aaaaaatggc cgaaaataat atgaaacaag
   119881 tgtactttcc aaaagatgct atagtactaa aaaataataa tggtacagct ccaggggcaa
   119941 ttttagaaaa agatggtaaa tttataatag tattgcctgg acctccaaga gaaatgaaag
   120001 ctatgtttaa tgagagtgtt aaaccttact tacaacaatt cacaaatgaa atgctagtat
   120061 ctaagacttt aagattatat ggaataggtg agtcaaatct agaattagaa attctcgata
   120121 taattaatga gcagactaat ccaacagttg ctttatatgc aaaagaatta gaagttacaa
   120181 taagaataac tgcaaaggct gaaaatgaaa gagaagcttt taaattaata aaaccagtag
   120241 aagaaaaaat aaaaagtaga gttggtaaat atgtatatac tgaaggagat atttccatat
   120301 ctgaagggga gactgcttta gaagatgctg tttctaagct acttgtagaa aaaaatctaa
   120361 caatagcagt ggctgaatct tgtactggag gtttggtttc ttcatctctt ataaactatc
   120421 caggtatatc ctctgtattt cttgaaggtt gtgtaacata ttctaatgat tctaaaatga
   120481 aaagattagg agtaaaaaga gaaactttgg aagagtttgg agcagtaagt gagcaaacag
   120541 ctatagaaat ggctgagggc gttgctaaag gacttaaagc taatataggt atatctacaa
   120601 ctggagtagc tggacctagt ggaggaacca aagagaagcc tgtgggactg gtttatactg
   120661 caatatatat aaatggaaaa acaatagtaa agaaaaatat atttaatggg gatagaagaa
   120721 agataagatt aagagctact agagatttac ttaatgaatt gagaatacaa ttagaaaagc
   120781 tttaagttat tttgattaaa gtattagtaa aatataaaat tgttttggag gcttttaatt
   120841 tatgataaaa catatatttt gtgatttaga tggaactcta tatgaaaatg gaaccataac
   120901 aaaagaagat atagtagcaa ttgaagaaat agaaaaaaag ggagtacagt ttaatgttgc
   120961 tacaggtaga atttttaaac aagcacataa tattatcaaa gatagtttag atatgaatgg
   121021 atattatgta tgtgaaaatg gttcatttat atatgataaa gattataatg taatttttaa
   121081 aagaacgata gacgataatt tagtaaaaaa agtcattgat agatttgagt caagtgatgc
   121141 acaactttat tttaaatata agggtgatgt aattgtgggt agtgatacca ctgcttttag
   121201 acattattct agtgacttta tagttgaccc agattttgaa aaaagaagta gttttgataa
   121261 tcttatagga aatataggcg tatgttctga aaatttggaa gagttatcca gaatagaact
   121321 ttatctaaaa agtgagttta gtgaagtctt agaaatatat ttttctggaa catatacttt
   121381 aaatatagtt cctaaaagtg tgtcaaaaag aggaagtata gagcatgtaa taaaaacgtt
   121441 aaatgtaagt ccagatgaag ttgctactat tggggattct ccaaatgata tttgcatgtt
   121501 agaaggattt aaatatagtt ttgcaatgtc taaggcaagg gaagatgtaa agcaaagtgc
   121561 aaattatgta gtagatagtg taaaaagtgc catagatgtt ataatggaga taaatagtta
   121621 gtataaaaaa tgactgtcct agagaagtat aaaattatat tctatagagc agtcatttta
   121681 attatattca attataagtt tatataagtt taaaaattct taagttaacc gcaatttgct
   121741 atatgatatg attttattgt attagataaa atagagtcaa gtatataatt tatgacacta
   121801 ttacaagtat aagctgaaaa ttttaaatca ttcatataat cagttttctt tttgtaatca
   121861 ctataaagtt tagtaaaaaa cttctcaaaa ctactattta tagtaccaca tttaatttta
   121921 gataaatcaa catcttttgc aaatgctcca agttctcttt cataagtaac atgtttattt
   121981 aagctatgct taaactccca acgttcactg tgagctacac agaaaaaatc acataaaaaa
   122041 tgacatatga ctcctagttc ctgactaagt ctacttactg aaaagtattt agaaagacta
   122101 tctatattaa gactgcatag atagtttatt ttagaaacaa tcatattaaa tgactcatct
   122161 aaataatgtt tttttaattt atatttagaa aaagcatcag gctttatatt gccatatata
   122221 aaattttttt cgcttataaa gaatgtttta ttttcatcta tattatcaag tattgatttt
   122281 gccataataa aatgggtatt cattaacata tttacacctc gtatagttta ttagacttat
   122341 taaatatatt attatgatat gatatttatg ataaaagttt aatggtaaat atatgaaact
   122401 aagtcaacag tatttattta aataatttca accatattca taataacagt aaatggccaa
   122461 atttacaata tgtaaatagt gttaagtttt tatttatcaa atttaaaatt aagtattagt
   122521 atactttcta attaacctat tggctttaga ctgtgagatt tcaaggtgtt tggctacttt
   122581 ataagaacta ccaaattttt cataagcatc caaaattata tttttttcat actctttaat
   122641 taaagtgtca aaatttttat ttttataatt agtagatttt gagtcagata taataacctt
   122701 attaatttgg gatatatgtg ttttatttcc attattggta atatgtatat tttttgtaag
   122761 aatgtttggt aagtcatcta ttgttatatg attatctgta caagtaagca agattttttg
   122821 aattatattt tgtaattctc ttatattgcc tgggaatcta taatttgcaa tagcatccat
   122881 agcttcttta gaaatagttt tatttagatt gaagtcactt gagtacctat taaaataata
   122941 ttttataatt tccactagat tatcccttct ttctctaaga ggaggcaatt ttatttctat
   123001 aacatttaat ctatagtata aatcttctct aaactttttt tcttttactt ttgaaactaa
   123061 atcaacattt gtagcagata taattcttat atcgaccttt ttatttttta agctcccaac
   123121 tggagtaaaa gttctatcct gtattaattg caaaaatttt gcctgtagat tttgtggtat
   123181 atctcctatt tcatctaaaa aaagagttcc tccattagct aattctacga gcccaacttt
   123241 acctttagta cttgcacctg taaaagcacc tgaagtatat ccaaaaagtt cagattcaag
   123301 aagttgtgga gatatagttg cacaatttat tgttataaat gggccattag atctattgct
   123361 gttgtggtgt atatatctag caagtgagct ttttcctgtt ccagattcac ccaataaaag
   123421 tacacttaca tccgttttag aaacatgatt tactgtgttt atgattggtc tcataactat
   123481 tccgtccata attacagtat cctcaattct aagtgcagtt ctgtatagtg tttctacttc
   123541 agatttatat ttttttactt gtttttttgt gtcttcaagt ttatttttta tattattaag
   123601 ttctgttata tctctacaat tttcaacagt aaattctaag tttccatttt catcaaatat
   123661 aggggtagca gttatgataa gctttttccc tgtttgagta tcttgttcca gtgaaaattt
   123721 agtctttgtt tttaatacaa ttggtatggg gctttttgtt gaatatccag agtcttctaa
   123781 aaaagaaaca ttttttccta aaatatcttc tttttttaga ccataatttt cttcaaatgc
   123841 tttattacaa tatattatta ttcctttatc atcagaaaca catatttcat catgggaagc
   123901 ttctaatatt ttttgataaa attccaaatc taatttcaaa tttaaattca tttttatatt
   123961 ttcctcctaa atttttaatg atatattaaa atatgtttaa ttgattaata tacttaaaat
   124021 ttgatattta tatataagtc tcagtctatt ttaactttaa ataagttata tataactcat
   124081 tttacaatta aaataagtct aaatcaactt aaagtaagcg aaaaaaatat aagaaaattg
   124141 aaaacttatt agtattattg gaaagactag ggttttagag tcgatatata ttggtttaag
   124201 atggcatagt ttttgcttaa taaagaagag tgtaaattga ctaaataaaa atagaaggga
   124261 atttaaaatg ggagaaaaaa gtaaagggta tgtatttata gcaatagcag ggttattatg
   124321 ggctacactt ggattatttg gaaagttttt aatgggaaat ggactgacat cagaacaagt
   124381 agcatttaca agattgtttt ttggatttat agttttaggc gtatattcat ctataaggac
   124441 accacaaatc ttaaagataa gcaaaaaagg aattatatat tcagtaataa taggtattat
   124501 atgtcaggca atgtttaatt tatgttattt taaagcaatt gacattgcgg gtgtatcaat
   124561 tgcagcagtt ttactatata catcaccact gtttttagca atattttcaa aagtatgtta
   124621 taaagaaaat attactagaa gcaaattatt ttcacttatt ctttgtttta ttggtgcaat
   124681 tatggcagtg actggtggac gtttggattt tcaaggttta aacgcttttg ggcttttact
   124741 tggggtatta tcagcaatag catatgcact tatgccaact attagtaaaa atgctttaaa
   124801 ggaattttca agttcaacaa tattagtata cagtttctta tttggagcta tatttatgat
   124861 tccttcttca agaccttggg aaatcttaaa ttatgctaag gatttagatg ttttatcttg
   124921 tatgctaatg ttaggcattg ttccagctgc acttgcatat attttttatg cagcaggtat
   124981 atctaaaggt gtagagttgt cagttgcagg tgttgtggca tcagtagaat tagttggttc
   125041 agtaataatt ggttgcacta tattaggaga aagtttttcc ttagggaagt tatttggagt
   125101 gatgttgatg ttaatatctg cagtagtagc acttaatctt tcttatgatg aaataagaat
   125161 attttataag tccaacaagt taaagcagat tgaaaaaact gaaagtattt agaattatat
   125221 acttaaaaag gatttattgg tatacatttt agagtccaac aaaaattata ccaaattata
   125281 tttggtatta aaaaataact atttataaat tttatagaat aaagtagaca gtacaaataa
   125341 aatataagta gatacagttt agattatcta ttttttatta tctattgtat aaatatacaa
   125401 attaatattt tgttttgtaa atactaaata actatagaaa tggttatata accatttcta
   125461 tagttattat tttgtattaa acaaacttac agccctgata agaatttcta gcctttaaag
   125521 tatcatcaat ttgatttaaa atttcccatt tttttaggct ccatatagga cctactagtt
   125581 catccctctt accatcacca gtgagtctat ggattatcat agtttcagga agtatttcta
   125641 attggtcaca gacaagattg atatattcat cttgttccat aagagttaac ataccatttt
   125701 gtaacatctt ttccatagga gtatctttta taacatgcaa tagatggatt tttataccgt
   125761 ctacacccat tttaccaact gcctttgctg tttccatcat catattataa tcttcaccag
   125821 gaagaccatt tataatgtgt acgacaacct ttatattttt agactttaat ttttcaacac
   125881 cttcaacaaa tgttttataa tcatgacctc tatttataat tttagatgta gaatcatgaa
   125941 ttgtttgaag tccaagttca acccataaat tggttctttt atttagttca gacaagtatt
   126001 ctacaacatc atctggcaaa cagtcaggtc ttgtggatat tgaaagacct atgacatctt
   126061 caagttctaa tatagtctca tatttttctt ttaaaacttc aagaggagca tacgtatttg
   126121 tataggcttg aaagtagcca atatactttg catgaggcca tttttttaac atcatttctt
   126181 ttatattata aaattgactg ataagattat ctttagggtt tccagcaaaa tcacctgagc
   126241 cttctttgct acaataagta catccgccat aaccaagact tccatcaatg tttgggcaag
   126301 taaatcctgc atttatagat accttaaaaa ctttttctcc aaaagtattt ctaagatagt
   126361 aattccaagt atgatatctt ttattatcaa aagcatattt aaatttatcc aaaaaatcac
   126421 ctatttctaa taaaattgta cgctgagctt gtacaaaaaa catattacca caaatagata
   126481 acttaaacaa attctatttt aagtaatata aaaatacagc gagaaaataa ttaatatttt
   126541 ctcgctgtat ttccagagaa aaatagaact agtccaaata atattatgaa aaaagacatt
   126601 atcgatacta taaatctaga taaaaaaagt ggagataata taagacatat accaaataga
   126661 atcttaacta tattccaagt tgtaaattta gaataaggat tattcttact atttacaagt
   126721 gctactagtt gattaaagat taaataaaat cctaaaaata atgaaaatat gctttgtatt
   126781 ttttgaggaa atacaaaaag taatatacat gcaattatta aaacccattg gatattaata
   126841 gagggtttaa tttcttcttt agtagcatat ctttttagtt cattaatatt ttttaaattt
   126901 aaatatgcaa agaataaaag tgcaatacca aaagtccaag aaattaattt tatacctaat
   126961 gtcttaaatg taaggcataa taatcctaat ataatgagta atactcccat taacataaat
   127021 ttaatggcat tttctttttt attaaagtta ttaaaatcga tattaaaatt tgtgtacata
   127081 aaatcacctc caaaatcgat agaacaatta taacagaaat tcatatccaa ataaagccta
   127141 gtgtataaaa attaaactat acttagtaat taattaatag gttgtatcat aaacttctat
   127201 taatagaatt atatagaagg aggtttgtcc atgacaaaat tatgggcaat aatatttgca
   127261 ttattagcag gtggttctac agctcttgaa gcttttataa atggagagct aggaaaaagt
   127321 acaacagcat tagtggccac ctttataagc ttaactgtag gagcaatatt ttttttggca
   127381 agtataatag ttacaggtga cttaaagtgt ctagtatcta taaatggttt taattataag
   127441 ttgttattag gaggagtatt tggaggtcta ataatatatt ttacagtaaa ggcaattcca
   127501 aatttaggag tatcaaatac acttatatta actcttgtat cccaagtttt agttggattt
   127561 tttattgata gcgtaatttt gggacaagaa acaatgcatt tatacaaata cgtaggggtt
   127621 atacttttaa tattagggac attctttata gtgaattaac aatttaatat aatttgctat
   127681 gcaactcaaa aatttggtat aattatgtta ataaaacaaa gttagatgaa agaggtgtta
   127741 aaattggctg atgaaaaatt tgtaatgtca tttagtggtg gtaaggatag tatattagca
   127801 ttaaatcgaa tgttgaaaaa aggatataag cctgtggcac tcttgacaac tataagtgaa
   127861 gaacatggaa agtcatggac acataattta gaatataata tgcttaagca agtaagtagc
   127921 aatataggat tacctttatt agttgctgag tgtggtgtag aaggatatga agagagcttt
   127981 gagagggctt taataaaagc taaaaacatg ggagcaacga tatgtgcata tggagatata
   128041 gatatagaaa gtcatagaaa atgggatact gatagatgtg aagcagttgg tatgaaagta
   128101 gatttaccat tatggcaaga gagtagagag gatttagtat atgaatttat agacagtgga
   128161 ttttgtagtg ttgtaacaaa agtaaactta aagcacttag gagaggaatt tttaggaaaa
   128221 aaattaacta gagaacttgt ggagaagata aaaaatgctg gtgcagaccc atgtggagaa
   128281 catggggagt atcatacatt tgtcgtagat ggtccaatat ttaaaaaacc tgtagaatat
   128341 gaagtaaaag gaactttaat aaaagatggc tatggatatt tagaaataaa ataattacat
   128401 aaataaaata cctattatat aatcctaatt tttgcaaagg tctaatattt gcaagattgt
   128461 ataataggta ttttttattt agatattttc atatattgtc actcttatca tctaagcaac
   128521 cttatttaga ttagagtcta atgtagaaaa attctttttt agaaaaacta atgataaaat
   128581 aagacatata aactcagaaa caatagtagt catccatatt ccttgtccac caaatattag
   128641 tatcattgaa attagactta aaacaactat tacaagccct ctaccaagag atataacagt
   128701 agaaattgat ggtttttcta ctgatacaaa gaatccagaa attattacat taattcctac
   128761 caataagaaa gatatagaga atattttaaa tacacgaact ccttcattga atagcattgt
   128821 ttcttctgga tgtataaata aagagactat tggtcctgaa aaagccatac aaattgcaaa
   128881 tacagcaact gatgctatta ttgtggcttt tatccccatt tttaataatt tttttacatt
   128941 atctatattt cctgcaccat aataaaagct agtaagtggt tgcatacctt gagttatacc
   129001 catcatagtc ataagtacta atgtatttat ataatttatg acactataat aaataagagc
   129061 attttctcca atatatttag taagacttaa gttaaaaagt aaaacaacta taccacaact
   129121 taattcagta gttgaatcag gaaaacctat aaatacaatt tttctaagtg tcttaaaatc
   129181 aattctaaat tttgaaaaat tcaaagtaga gttttttctt aaaaaatgta ttaagaagaa
   129241 aatagtagaa aagacttgag acaaaccagt tgcaatacca gcacctttta caccccatcc
   129301 aaattcaatt acaaacaagt aatcaagtat gatgtttgta agagcagata ttattacacc
   129361 aacagtagct aatattggaa agccatcagt ttttattata acttctaaag aataagacac
   129421 tataaagaat ccgttaaaaa atattattat tcctaaataa tctttaacca taccaattgt
   129481 agattctgta gctcctaaaa atagtgctaa tctatctaaa ttaaaaaaag ttatagctaa
   129541 tataattatt gataatataa ttattgatac taagttaaat gaaaagactt cgttagcaga
   129601 tttaatatct tttttcccca gatagattgc aattatggta gatgcaccag ttgaaaataa
   129661 tagagaaact gcaaatataa aattaataaa aggcattgat atattgacag cagctaaagc
   129721 taattctcca actcctttac ttacaaatat tccatcaacc attgtatata gtgagaaaac
   129781 ccacattgca actacagatg gtgctaggta tttaaaaaat cttttaccta gactcatgtt
   129841 ttcgtttata gatatttttg tatccattta ttatcactcc ctgtaaatct attataaaat
   129901 tacgaaacta ttaattaata attttatttc taatataaat gataaactat ggtataatac
   129961 caatgtcaac aacaaatagt atataattat aaattttatt aaataatagt gattttaagg
   130021 gtcttataaa tatatcttat ttatatatta ctgacattta actgacaaat ggaaaaaaag
   130081 cactttgagt gacatttaat tgacataaaa ctgaacatta tttgaatagt attttgctta
   130141 tattttcaga tgtttcttta tccatttcat ctaataagtg agaatatgga atatatattc
   130201 atagctattt ttatatctgc atgtactaat attttataaa tagcttttat gttagtacct
   130261 gaaagtaata tcaaagtcgc atttgcatgt attaattcat gtacttttat atctctagga
   130321 ttattatctc ttaatagttt tttaaaatga acaacaaaag ttggttgaac tcatgggttg
   130381 aatcttttat ttaagcatat caaatcaaat tcatttttca atataccctg taattttaac
   130441 ttattttgtt ttaaattttc ccctttaagc aaacttataa gttcatcagg agcaaataat
   130501 tttcttttgg atataggggt tttagggtct ttgaagatta ttttattgta tacataaact
   130561 aatgtttgat ttacatgtga gattttttat caaggtctac atctgaccat ataagtgata
   130621 cagcttcacc aaaacgtaat ccaagagtta gcatcaaaaa aattggtata cctataggaa
   130681 tattttttga tttttctaat aataattgag ctttttgttt tgtataaagc ttagaagttg
   130741 aactactttt ttgattgggg ttgtaacaaa tcgaggatag agtagatgta tacagaaata
   130801 tatagacgaa tctttagaaa agtaatatat aggtaaaata tgtaagaatt atatgctata
   130861 acatttttag caaaaagatg taatctacaa tttatagagt ggagttcata caaaagatta
   130921 tcctcccaat gtatagaagg gaggtgagta tgtatggata attttttaca aggtgtacta
   130981 gcaagtttag ttgccagttt aatagtttac ttaaatagta aattatttaa aaaagtaaaa
   131041 agccactctg gcaggagcga ctttagtttt gaactaaaaa tcaagttcaa aaagaataaa
   131101 cattagtatt tgaacttcac tctacgtcta aatagattgt agttcttctt gtttttatta
   131161 taccacaaat tggtacagat attcaaaaat aatatattta tgatataata aaaatgtaaa
   131221 tagttttgca gtgagcgata tttgttacaa agtagggctt aatgcttgaa atataaggtg
   131281 ttgagggcat gtgataagct ttatcatttg cactactcat ggttcactgc aaatttaaga
   131341 gagttgcaca tgtgtaagca ttgaaaatgc ccagtttatt ttggggtttt atattaacta
   131401 agtggtatgt aaattacgga gcgaccgtgc ttaacactgc aatagcatct ggttttatat
   131461 taactaagtg gtatgtaaat acttatgaaa aaaagaaaag gggattggga cagcgagttt
   131521 tatattaact aagtggtatg taaatgaaaa tcaaactctt gtgtgcatcg acgaaggtgg
   131581 tagttttata ttaactaagt ggtatgtaaa tgttatagtc ttttggataa ctacccaatt
   131641 aggatttgtt ttatattaac taagtggtat gtaaataaaa atattataga tacaaaaaaa
   131701 gattcagaaa acagttttat attaactaag tggtatgtaa ataagtcaca ccgccctcca
   131761 cacgacacta taataatagt tttatattaa ccaagtggta tataaatagt ataatgttga
   131821 aaagttagag agtacaatca agaaatttta cattaactaa aatgtataga ataaaacatg
   131881 tatttatact taaattctgt acctatataa aaaagtgaac tctgtcaaca aagcactttt
   131941 ttatatagat aaattatcat tttgttttaa gatagaagat actaatgata actgtttatc
   132001 attagtatct gtatgtacat aaaagtttaa ttttttatat aaatttgctc tttagaaaaa
   132061 tgagcagtat caataaatat attgtctaaa ttttttctag gaactagttg actagctata
   132121 agattagctt caactctttg attgttagac tatgaaatta aatttaaagg ttcattcttg
   132181 gtcgtataaa tagctttatt attcgtatgt actataacaa tttttgccat ctgcttttga
   132241 tagataaaga gctttatcag ctttagaaaa taaatcttta tataatttag ttgaatcatc
   132301 agtgaaggca ataccaatac ttaatgttat tttatgattg tcctttactt ttattttact
   132361 cgcatcattt aaaatatcat tagtaatttt tattattaaa tcctttgtta atgattttat
   132421 aaatattgta aattcatctc caccaattcg agcaactatg tctttatcat gtgtgttatg
   132481 taatagtatt tttgatacag caactaaaac ttcatttccc tctaaatgcc caaaagtatc
   132541 atttacagtt ttaaaatcat caatatcaat aactaataga gcatcattat ttttggaatc
   132601 agaactacat agatactctt caataagatt ttgtgatact ctttgattat ataattgtgt
   132661 tagtgggtca cgttgagcct gattaattaa gctttctaat ttagatttat cttcagttat
   132721 gtcttttaaa acgcctattg ttttgatagg gttatggtca ctatcatata taactgaaca
   132781 ttgaacacga atccatctcc attcattttt agttaatgaa tttacttgtc ttatctcaat
   132841 tgtttcacga agatttccat gaagtacttc tagtagtttt ccaatatcat caaggtgaat
   132901 aattttacca gattctaata gtttggagta attttttgtt tcaaaatttt ctaattcaat
   132961 ttttttgtca atttctacac gttgatattt tataagggta tcgttttcaa tatcatactc
   133021 aaacatgata tctgtaatat tttgcaaagc aatacgatat cgctctcttt ctaattttag
   133081 ttcagattct atgtttttta gttgggttat gtcagtaata atactattaa tttttactat
   133141 gccatcacta tttaacgatt tcattccaga atctaatacc cacattaatg ttccatcttt
   133201 ttttcggatt ctatattcag atgaatatgt aggtcctttt gcaaaacatc gttcacaatc
   133261 ttctagtgct ttaggtaagt ctggtggata tacagcaccc actgctgaac caccactcat
   133321 ttccatgaac tcatcatatg tgtatcctaa tattttgggc aatccctcat tgacatagaa
   133381 aaatgagtat gtactatcat cattgctacc ttttaagcca ccattgatat tatttgtaat
   133441 catttcaata acttctgttt tttcttttag taatctttgc aaataatcat aactttgagt
   133501 tccaatttta gtgggaaagt attcatcaag ttgcatttca ccataagggt ttgatatgtg
   133561 catgtgcttt attaataatt ttcctctatc ctcaattatc tcaaatgtac aacgttgatt
   133621 tacctctaaa atcatttgag cattttcttt agttcgaaca gtatatcttc ctaataccat
   133681 acatctattc tcatcttcac ttacagtttc aaatatatca ttatttatat cacaagaagg
   133741 aatttcatct tgacctgcat aaaaataatt ttttatttca ttaaaagaag tgagaaattc
   133801 ctgttctcct ggtccaatcc atgtaacatt ttcacaaagg tattttaata cttcattgat
   133861 atctcgattt atataaaaac ttgttataat atgttttgct aatttgggtg ctttttttag
   133921 gagtatgctc atgatattcc tcctttcttt ttgctattat attttaatta tattatacat
   133981 caatatattt aaattaaaag ctttgttaaa ctatgatatc tttgtcaaat aagttaattt
   134041 taacaaaaaa gaactgaaac aatatatgct tcagtattta atgtcaatat cttgtataga
   134101 tacatattta taaactaatg tacaagttta aaaaaagaaa gataatttta atttatttta
   134161 aaataacaat attaataatc atttttatca aattttttct tgtttttctc cttgttttta
   134221 tacatttttt tatccaattc aactattgtc aattttaaat ttctttttac tgtatcaaca
   134281 ccataactaa atgaaagata cttatactta gagaatactt ttaaaaaatt ttctcttaag
   134341 gcttctagct gtgaataaac ataatttttg tcaacatcac tagagaatat aacaataaat
   134401 tcatctcctc ctaattttat aatagaagta gaatttatta attctttatt taaaagtgaa
   134461 acaaaatcac ataaaatctt gtctcctaca ttatgacctt catagtcatt tatcattttg
   134521 aaattatcta agtcaattag tacaatataa tctcctataa atatgtcaaa tctatcattt
   134581 aaatattttc tattatatgc tccagttaat gggtcagtaa ttgagtagtg aagatttctc
   134641 ttattttctt catagagttt tgttatatca ttggccatag taattatgta ggttttttca
   134701 tcaacatcta ctttatattc taaaacattc caatagcttg tagtatcttt tttaaactct
   134761 aaaatccaat ttgaaatttt atcataagga taattttttt cccaatctaa ttgaatattg
   134821 tgagaatccg taaaaaattt agcaatatta tcagggagtt tcttagctat ttctatatta
   134881 gtcattccaa gtggattatc ttgcatataa cttttaatta aattttttaa attatcattt
   134941 ataaatataa ttctgtagtt agaatctctt ataattagaa atcctggaaa agttcttaaa
   135001 aaaatttctt taaacatatt aatttctcca aaataaaata ctttgtacta gatttttgtt
   135061 aaatttttta ttttatttac atctacatac ataccctggg caatcgacct tccatcaatt
   135121 gcagaaaggt tacattgtgt atacataact gtgacaattt gaccatctcg ttttatgaat
   135181 ctatataaaa atggttcaat tttatttgtg tcaatcatat ccaaactttt tttataaaca
   135241 aagtctaaat catctggatg aacaattgct cttaaatttc cgcccatctc accaaaaaac
   135301 tgttcttttg tataacctat aatatcaaac atttcttcat tcatataagt aataatcata
   135361 tcaccaaata aatcgtagcg aattatacct acaggcaaca ttgaataaaa ttgtgataaa
   135421 atattacttt catcaagatg tgtatttgtc attttaggta ttgaatatga ttcaaattca
   135481 tttatatagc cagcagtttt aattaaatcc aaatgtaatt ttgctaagag taatttattt
   135541 tctgaaatta tacaatttgc actaaagtag aaattactat atttttgatg ttcagcagct
   135601 tcatctgata aaacggcttc tccactaatt aataatgaat ctgattcagt attatgtggg
   135661 gttatacttt tgtaaagaat agaaaatttt ttacctttaa tatgtttttc aaaatgttct
   135721 attactttag gaaaagatgt aatttcagtt ttgttgtaaa aatcaaacca ttgaatgtct
   135781 tcagtgacat tagctcttag ttttttcata tcttgcataa taaaaaatcc atcaaatatc
   135841 ttctctatta aagattttcc tatatcagaa tattttataa acattttctc tgaattattc
   135901 tctttagata gtaatttttc aaattctttg cactccatgg gttttgcata ataataacct
   135961 tgggcgatat cacaatttat acttttaata aattctacat gttgttctgt ttcaacacct
   136021 tcacatactg taagcatccc aagagctctt gcaatgttta ttatagagta caaaatggtt
   136081 gtatttttaa aatcatttaa attatgagat aaaaatatcc tatcaatttt tattatatca
   136141 aaaggtagat tttgcaacat accaaaagat gaatatccag aaccaaaatc gtccattgat
   136201 acagaaaaac cataagaacg aagttcagct agttgttgaa taattgtatt tgtattttct
   136261 attaatatat tttctgttat ttcaatgcta aaatttgatg tagagacgct gtacttttca
   136321 gtaatacctt ttagcatact tggaaaatta gggttaaaaa aatgaagacg agaaaagtta
   136381 caacaaattg gaacaaaaac atcattgtta tcaatccatc ttcttatatt tttacagttc
   136441 tcttcaaata aatgcaaatc taattccgtt atcagaccaa actgttcaaa taaaggaata
   136501 aatttatctg gagtaagaag tcctttaata gggtgtctcc atcttgcaag tgcctcacat
   136561 ccaactatag tattattttt tatattataa agtggttggt aaaatacttc aatttgttta
   136621 gtttgtagaa catgtgatat ttctgataag aactccttat cattttctaa tttattgtaa
   136681 aaactattat ctttaaaatc aaatagaatg tatctatttt taccttcact tttagccttt
   136741 tttaaagcac tatatacttg gttgaaaagc atcaaagtat tcatgtttgg ttcaccattc
   136801 cagatagtgc tgccgatact aaatgtaaca ttggagtata tttctttttc attaggaagt
   136861 cttattttta attctcgggc gctctctata atagttgcac ccatattatt taactcttta
   136921 tttgatacat ttggaagtac aattaaaaaa ccttctcctt ttaaataagc gactattccc
   136981 tttgattctg gaataaagtg caataggttt tgagttagag taattaataa attttctcca
   137041 actaggtatc catatatatc attaaataat ttaaagttat cgatatttaa taacatgatt
   137101 cctatatgta tatttttcga aatacagtca tcaatatgtt ggtacataaa ttctctgttt
   137161 ggtattttag aaaaaaaatc tatttcattt aaggttttta atttaaaatt tctactatct
   137221 aattccttag ataatacttc taccttttta tttaacattt ttatataatt atgattttgc
   137281 atggtattcc tccataagat actttaaatt ttgatgacaa ctgtatttat gctagaagta
   137341 tttaaatgtt aatttgtaaa taatttaaat gctaaatttt aaataagtat ttaaaatgaa
   137401 tatacattaa gttatttgct ccaatgctac aaatacaaat attttttagt ttagtaataa
   137461 tattagataa aattagttaa tgcttaaatt ctagtatatt gaaagatttc ctttttgaat
   137521 gcaattatat catatttttt cataaataga tagattgtga gctgtatagt tagtaaggta
   137581 gagttttttt ataattaatt ttaagtttaa tgatttttca aaggcataat tattttattc
   137641 ataattaact ttttatacat aatttaatac catattaata attttgcata attaatttta
   137701 gttattaaaa ttaagtttat tcttgtattt tttgttaaag actataataa atattcattt
   137761 actaaattta taaactatta atctatagaa atcagtttta atatgaaaaa tattacatag
   137821 agatggatat aatagctgta aacataaaac tatataaaac taaaatatat ttataaaaaa
   137881 gttgaagtta taaatactat acctaatatt acaatataaa aatattttaa taattaatta
   137941 ttaggatgtt tattttccta tccttgtttt aaagattttt ttagtatatt ctaatactat
   138001 agtattatag agtaataatg ttgatttaaa ataaaaatag gatttcggag gagtttatta
   138061 tataaatgaa agattactat aaaataggag agatatctaa aatatatgga ataggtagag
   138121 attcattaat gtattatgaa gaaataggca ttctaagacc agttagagat ataaatggat
   138181 atagaatgta taatatatca gatatatgga aattaaattt aataaaagaa tttagaagct
   138241 tgaactttcc aatgaagaaa ataaaagaat acctagatga cagaagtata gagtctacga
   138301 aaaatatttt aaatgaagaa ctcgatttaa ttgataaaaa aatagctgaa tttataagcc
   138361 ataaggaaaa tattataaaa agattgagtt cgattgaaag tgtaattcaa aatacaaaaa
   138421 tagatgagat agaggttgta tatatagaaa aaagaaaagc tttagaatta aatgctgata
   138481 taaagaggga tgaagacttc gattttttaa ttcaaaaact tcagaaagaa tatgaagata
   138541 gatttaatat acttggaaac aacaatattg gttctgcctt ttctactgaa gcaattaata
   138601 aaggtatatt taatgagttt aaatctgtat tttgttttct ggaaagtaat gagaaagtat
   138661 ataatatagt ttttgatgaa ggatattatg taactttaaa ttatactggg agtaattcta
   138721 ataataagat atatatggag aaggtgttta aatttataga agaaaataat tataagataa
   138781 ttgctgaccc tatagaaatc tataagatag atatacatga gactggaatt gtagaggagt
   138841 ttgtaacgga aattcaagtt cctataacta aataactata tttcaatgga ttagatggta
   138901 aatagaatga aaaaatgttg atttgccacc gatttgtcac tgtattataa aatcggtagc
   138961 aaattatatt ttaaattata agatagcatg aaaaaataat tgtttagggg gttataaatg
   139021 tgaaatgttc taattgtgga agtgtaaata ttgaaaaggg aattttaaca actggtggca
   139081 tatatgctga aactattgga ttaaaatata gaggagatgg aaaattagat aaagttataa
   139141 ataaaacttt tccagtacaa tctactatat attcagattt atgtttagat tgtggcgaaa
   139201 tagttagaac ctatataaag gataatactg ataggaattg gtgtaaagat aagaaataga
   139261 ataatttttg aagtatatta atatttgaag ttgaatttta ttaaagatat aagtgaaaaa
   139321 gtataaatgg gaagaaattg ttatatggaa gaaactttgc atatagggga gattagtttt
   139381 ttaatataat aacattttta aatgtagata aaactaaaaa gggttctcta gaaaacaatt
   139441 tctatttaat tatacttact taccaatacc atcacttgat gtaaacaaga ttctactaca
   139501 ttttctccgt actctagtat aaaatcatct agctgtgtat ctataaaatc acaataatca
   139561 tataaactac taatataagc agttaacatg tgtgtacatt tatccatttc atctctaaac
   139621 atatatatta ctatccccct aaaaaacttt cataaaacaa aaagaacaat atctttttgg
   139681 caactggctg acataactca tagtttattt tataagcgtt agtccctata gctttgcgtc
   139741 actaaatttc tctagttttg ccgatttagt tttattctac aactaaaata atacactagg
   139801 ataagttatt gttcaacata cttgtcagaa aattgaaata tttaacaata tcttaacaat
   139861 atgaaatcta tttttcactc aagaaacaaa ctatgtatgt agaatgttta ataaaaatta
   139921 tatttagttt tgtattgaag tttttgtatt aaaaagttta gttcacaagg gttacttggc
   139981 tagataatag ataaacaaaa atatcttgaa aaaatatata tgaatggcaa aaaacaaggg
   140041 atgaatttta tatagactca tcccttaatt atttatatat tgaccttgat taaatatatt
   140101 attattttta agcttcaatt tttatattat atttctaaag tttctataag aggattatcg
   140161 ctaaataatt ttaataaatt tgttttttta tatcctttag gtaacttagt atatataact
   140221 acttctaacc aatccccatc aaggcgttta atattcatgt ttataatttc aatattagat
   140281 tttttaaatt taccttcaat atattctatg gaatcagtgc tgttagaaat tttaagagaa
   140341 acttgctctg ctgtagggag tttcatccat ttcctatctc tatgaagtgt tatctgtaca
   140401 ataacaataa tgatacttga aacaatacca actaagtata atccagagcc aatggcaaga
   140461 cctgtaccgg ctgtggccca tataccagca gctgtagtaa gaccacttac tgattgattt
   140521 ctaataaata ttaatccagc acctaaaaaa cctataccac tgacaacttg tgctgcaacg
   140581 cgggctgggt ctagaccaat acctggagta cccactatat cattaaatcc atacttggaa
   140641 acaatgatta taagtgctga agctaatgcc actataaaat gagtgcgtat tccagcttct
   140701 tttagtctat tctttctctc atatccaatt aaagccccac agaaaccagc agtaatgatt
   140761 cttgctatat attcaaattg aatcaatata tgatggttca tttatctagc acccccttct
   140821 atataatatt atatatacta taatactaca ttttttatgt gaatatagta aagtttaaaa
   140881 tttatataat agttatatat gaatataaaa tgtataaacg tatattatgt atataaaaat
   140941 gatagaaagc atctaatttt aaatgattaa agagcaagct taaataaatc aaacttgctc
   141001 ttttaacata gtgtatgttt ttatttgtga tagttagata aaaatttatc tgtgtttttt
   141061 acatctgcaa aactgttctg tagtgatgcc atgaatactt gatgtacagt atttatatat
   141121 aaattatata tgtctttttg actatctttt tatatcttct taaatgtccg caaagcctta
   141181 ttttataggc tctacgggca tttttctttt gtggtaaacc tcacatatct aggtctatct
   141241 tcttatattt tcgctatcaa gcgtggttaa aatcgtggta aatacttctt atgcgattag
   141301 acgctgaacc tctgattttg cggtatctat ggacgcatga gcgtaccagt tcattgttat
   141361 actgatattt gaatgcccca tgatatactg taaatctttc gggttcatgt tcttgcttgc
   141421 cagtcttgtg cagaacgtat ggcgtagcgt atgcggtgtg atatgtggca agggattgtc
   141481 cttgtgttgc ttgttgtatt tctttaccat acggacaaat aaggcgttgt aatcaatcgc
   141541 aactttcggc ttgcctttct gattgacaaa taggaagttg ccccgtccgt ctatcacaaa
   141601 tggttctgcc tttgggcgtt tcttcatcac tcgttgaaat gcttgtatcg tttctctgct
   141661 taatggcact tgccttgttc cgctctttgt cttaggcgtt tcaatataat agccctgttc
   141721 tttgctcttt agtaactggt ggtcgatact cacaacttca ttcttgaaat caatatcggc
   141781 tactgtcagt ccgcacagtt ccgagatacg aagtccagtt ttcaacaaaa tcagcacatc
   141841 atcataatgc ttgtgataca cattgtccgt cttgataaat gagagtagga cttgttcctg
   141901 ttcctctgtc aatgcgactt tctctttggt atcattttct aggacttcac ttaacttgaa
   141961 atcaaaggga tttttcctta cgcaatcgtc ttgtatggcg atatagaatg acgcttttaa
   142021 cgagcgttta tggttgttaa tggtgttata ggaaaagcct ttgtctttca tgcgtaacgc
   142081 ccattcttta gcgtcagagg gttttatcgt atcaatgctc ctagcaccta acttgtcctc
   142141 tttcaataac cgcatgagtt gttcccgttg tttctgtgtg cttttcttca cgtttgccct
   142201 ttgtgcgttc tgtttggtgt agagttggca aagcgtcatt ttcttgcctg tgctgtcgat
   142261 accgtcctca atatcccgtc ttatctgctg ttccagttca cgaagtgagg gtttttcccg
   142321 ttttcccttt ggtgtcgggt ctgtgggtgt caatctccaa gcatacacat attttgtgtt
   142381 tccaaatgcg tctacatatt tatataagta ttttccgtct gttcgttggc tctctccagt
   142441 atgcaggata cgtcctttgc tatcccgtct tttttctttc atggtgtctg ctcctttcct
   142501 tgttggaaag agccttgata tgacttgtgt tcatcataac acatacaagg ctcatttgca
   142561 ttagattgcg tccaatttat caataacctg ttcaaactgt cggcgtttaa tctgtatgtg
   142621 gttgccattc ataatgagcc agccagcgtc cttgttttcc tctgccaatc gtcttaactt
   142681 gttttctccg atacggaaat actttgacgc ttcttcaatg gtaagggtgt atttttccca
   142741 tacgggaata tcgttgttat tcatcagata ccccctttcc catgtttcgt gtcatactgg
   142801 atatagggga taaggtcggt gcggtttatc ctctgtaaat gggcggttaa tttactggaa
   142861 agggaattac tgtatcttgc cttatcaagc atagttccca ctttttccag tccacctaat
   142921 gcgtcatgtt cttccaagaa gtaaaaactt ttgacagcgg aaatcacgcc accctctgtg
   142981 agccattgct gtgtttcttc aagggaattt tgctgttttg gtacttgcag tttcaagact
   143041 tccacagccc ctaaaaaacg ttcccaaaac cgacacgttt tccatctgct cttattactt
   143101 tcgtttctgt ttggcacgac aaagcgtagg ttgtttgcca ataacccgaa agccagttcc
   143161 ccaagttcca gtggtctgtc tttgaatgtc atggcaaaag catgagcctt atcatcacgc
   143221 agttgcattt ctgtccgttt ccaactgccg acttcatcaa gcgtcttatt atgttttgaa
   143281 cagacttcct tatccttatc ataaaagcgg tatgacaatc ccgatttacc agcaccgata
   143341 taaacagtct ttgcggtgtc gaaatcgtca aacttgcttt cgtcaaagtg gtagccctca
   143401 ctattggaga taaattcctc tttttcgcat ttcttcttta tctgctctat ggtaaaaaat
   143461 ggcttttcct tcttatcatc aatggcaata tccagtctag tgaaatggaa gttatccact
   143521 ccgtatcttc gctcacaacg tcggaacata tctccaaagg tataattcct actgtcgaga
   143581 atacggaaaa tatcatcaca acctctgccg gtcataacaa gataacagcc taacccttgt
   143641 gggttgtcct ctgtctttct tgcgtccccc gatacataaa tatctccaat ctgccagcgt
   143701 gcttgatagg ttttgtattt aacgcttgcc ggatagacgt tgaaaatatc agtcggtaaa
   143761 cctaaaatgt gcatgattac atcttctgcg gttgccgttt caaatacaat gctgatgtaa
   143821 tcaatcttaa cggataaatt tttgtgtgta gttatagtgc atttctcctt tcgtacttcc
   143881 cgtttttttg cggggtaaaa atcgtgtttt ttcctttatt tatcacagtt tctaggtact
   143941 atgacatgta tgcgcagggc ggtgttacat gtatgcgcag ggcggtgtta catatacgcc
   144001 ctttacgaac gcctaaaggc gttccctttc ttcctgtgtc tgtcccgttc ttaacgctca
   144061 cgagccttgt aaggctcgtg gctaaacgga acagccccag tcagaaacct tattttcggt
   144121 ctgatagtcc atgcttattc atgctatcaa agtgaaaata tctattctat atgcttactc
   144181 aagcgtgtga ttgaccctag cgtgcttaat cactctatct gatacgataa taacgccatt
   144241 agaattactt gtcaagaagt ttttgttgac ttttagatat atattaagta tgatatgctt
   144301 ataactaccg agaaaagcaa cgaaaggagc ggttatacta agttatggag cattatgaaa
   144361 agaaaatcag tttcttagga gagaacatac agaccataag aaaacataga ggaatgaaac
   144421 aacaagaact tgcggacaaa atcggtatca atatgcagag cctttccaag attgaacgag
   144481 gtgtgaatta tcctaccttt gatacgctgg aaaagataat ggacgtgctg ggtgtaacgc
   144541 ccaatgaatt attgtcggga gaatggaagt atgttaatca agccgaaaaa gaagtctgcc
   144601 agtttttaag aattgaagaa cgactaaatg cagaactaaa acatggacat tatgacaact
   144661 tctttgacag cgaggaagaa tggctggaat atgagttgga aaagttacgg gaatatatta
   144721 ccgactacat caacggaacg agcattgaag cgtccgacct ttacccaatc aaagagttta
   144781 tccagcattt gaagtttcaa aaactgctag accgctatga tgatttatac agcatggata
   144841 tgtttgggga aagcatagag ggacataaat ataggacacc ttatcaagtc gtaaaaatga
   144901 taaaccccaa ttcaaaagaa gatatggaat tattacggga agtattgaaa aataaccatt
   144961 ttgatgatga ggacgaataa cttttttcct ctttgtagaa gatacagcaa acaaaaagcc
   145021 tagatcaaga gtgcaagcac cacttctaaa gaagtggcag gctcttgaca tggctttttc
   145081 ttttctgttg tggataatca agaggaagaa aagataaaat ctgatttgtg gtaaatcgga
   145141 taatatcaat gaaattgtca cggtacaagt ttgggctata taaggatagt aactggaaga
   145201 ttgtagggta atcaaaaagg catgtattta aatcagagat acacgtcttt gaaatgaaca
   145261 aaattcattg aattttgttc attgacaatc gttcattcac gagatataat tttagtgaaa
   145321 ggagttgatt acatgaatat tacgaaacaa aaatcacaaa agacttttga taagcaagct
   145381 gccgattatg atacaaatat tcagggagaa catgctcgaa aactctataa gccgattata
   145441 gaaaatttaa aaaataagaa tatacattct atattagatt taggttgtgg aacgggtgcg
   145501 ttacttaaag aaataaaaga attaaatata gcagaacaac tatttggaat agatatatct
   145561 cccaatatgc ttgaaattgc aaaaaataaa ctaggaaatg atgcaacact tatcttaggc
   145621 gattctgaga gattaccttt tgaagatagt tcttttgacg ccattgtatg taatgactca
   145681 tttcatcatt atccacaacc agatattgta gagaaagaag tgtctaggtg tttaaagcaa
   145741 aatggagtat tcattatcgg tgattgttgg caaccaatcg gagcaagaca gataatgaat
   145801 tactatatga aacacagcaa tagtggagat gtaaagattt attcaaaaaa ggaaatgttg
   145861 ttattattat caaaagactt ccacgaaatt gaatggaaat cttttggcac aagatcttgt
   145921 ttaattatag catacaataa ttaaaccgca agaaaggaaa gaaaacaatg cgtatttcaa
   145981 aagaaccaga ggaacgtaaa caagaaattt tagaaacagc cattaaatta tttagtgtaa
   146041 atgggtttga aaaaacttca atatcagaca tagcaaaaga aattggaata gcacaaggat
   146101 tatgttatag atatttccca tcaaaagatg tactttttca gtctgctatc aatgaatatt
   146161 caaatatttt agtcgccaat atgacaaaaa atataaatat aaaaaaggat agtttaaaag
   146221 atattttgcg gaagatgata ctttttgcag aacaagaaga tgatacatat tatccagttt
   146281 ttcataataa ccaaaataaa aatttccata atttattaac attgaatgta tgtgaaaaac
   146341 tttttcctat tgtatctgaa attattgaaa gagcaaatta cacaaatgaa atacaagtca
   146401 atgatgttga aatgtatgcc agtttttgca tatatggaca actaggaatt attttaaata
   146461 ccgatatatc aattaaagaa aagagtttac ggataaaggc attttttagg gacttgttta
   146521 ggctttaaat cttcccctgc caaaaggcag ggaatattta aataaattaa atgaataatt
   146581 ttcattcaat aggaggaatt aaaatgaaca aaaatattga ttttgtaaac ggaaacacaa
   146641 aaaaatgttt acttgaaatg actgttccta tgataatagc tatgttttta aatatggcat
   146701 ataatctcgt agacagtctt tggattggaa atttgttagg tgagcaggca tacgcagcgt
   146761 taacaaattc gacacccatt attttaatct taacttcaat tggtatggga gcaacaaacg
   146821 ggttagccat tctattatca caggtaattg gtgcgaaaaa tgagcaaaag aaaaagaata
   146881 ttatagttac ttcttttttt gtatctataa ttctttcagt gtttatgaca attgtgttgg
   146941 agattttttt agagcctatt ttgatagttt taaatacacc gactgaaatt tttgatatgg
   147001 caaaaaatta cttatctata tatgctttgg gatatgtagc agtttatttg tatttatact
   147061 ttacagccat tttaagaagt tttggtaata ctatgtttca agcaattgca atgcttgtgt
   147121 ctactttatt gaatgctatt ttagatccta ttttcattaa cataattggg tttcacggag
   147181 cggcaattgc aaccttaata tcacagatta tttgtttggc gtttatgtgc atttatattt
   147241 atcgcaaaaa attatttaac ctttcactat ctgattttga tacaacagag attatgccgt
   147301 ttataaaaaa tgctgtgccg tctgtcattc aacaaagtat tcctgctatt agtacaacat
   147361 ttttaactgc tattgttagt acttatagta tttctgctat tgctggctac ggagttgcag
   147421 gaaaattaga aatgatatta ttttatcctg ctatggctct taatatggtg ttgacttcaa
   147481 tcgtaggaca atgtattgga gcacaacgta tcgacagagc aaagaattat ctgaaattag
   147541 cgttaaaata tggtattgtt gtttcaagtg tattatcagc agttgttatt ttcttctcta
   147601 aacagttggc aaaattgttt gtttccaacg aagctgtaac aaatgttgtc agccattatt
   147661 ttttaattgt tagtatcggt tatgttcttt acactattac tagttgctac ttaggtactt
   147721 taaatggtat aggaaaacca gcaaaaagta tggtactaat gatattctac tatattatta
   147781 ttcgtattcc ttttgcctat ctgttatctt ggctggcaga aaatttaaat ggtgtttgga
   147841 tagcgatttt aatcagtcac atagtcgcct gcattataac tattttaaca agtaatcaaa
   147901 ttattaagcg gttatatggg aaactttatg ataggactaa aaaagcaaga tataaaagca
   147961 ttgaaagtaa ctgctgtgga aagttttagg aataatctta tacgattatg cactacccaa
   148021 cagcatttta tcaacaacta aatattttac aatattaaaa gttcgtacag acggtatatt
   148081 ttgtacggac ttttttcttg ttcttctttc tgtattttcc aaagatatag acggtatctc
   148141 cgtttatata gttcagcgta tgcggaaagg aggtgagatt atgaacacat cttctttcga
   148201 gcatatcgtt agaatacagt ttaatgcttt gatgatgact gttattaaat gcacagtaaa
   148261 aaacagaaac agacagtttg caagacgttc caagcgtgaa gttttattct gtgaattatc
   148321 agatacgaaa aatgttgaat gcgtaactaa ggataactat tcttgtgatt acatttcgtt
   148381 tgaagtcttg aattttacaa ttcaaatatc aaatgagaaa cttgctgttg ctttatataa
   148441 gttatcgaat aaagagcgtg atgtaattct attacgctat tttcaaagca tgagcgacca
   148501 agaaatagca gaattatatc atgtatcacg ttctgctatt tatcgcagaa gaagtaacgg
   148561 attgaagaaa ctaaaaacag tattgaaaga aaggaattga accaatgaaa aaagagtatg
   148621 gctaccctac attaaaagta atatgtcaag cgtctgctgg aaatgaaact gccataagag
   148681 agattttgaa gttttatgac gcttatatct gtaaattatg cttgcgtccg ttttaccact
   148741 ctgaaagtgg taaaatcatt atgcaggttg atgaagaatt aaaaggtcaa attcatacag
   148801 aaatgatgaa agcaatcttg aaatttgaaa tcagagtaaa ataatcatac tacatgaata
   148861 aaaaacggga gatacacaga tatttgtgct atctcccatg ttgttttttg tgtcatatca
   148921 aggctcattc aatcgtggta aattcgtggt aaaatgaatg gttttctata cttcaaaatg
   148981 tttgaaagta tagtgtttat gcggataatc gaaaatcaga tataaaattt gcattaattt
   149041 ctatattatt ccaagataaa ttcttcgttg tacatgcatc gcttattaga gttatgtcgt
   149101 atcgaagttt ctttgctgtt cttacacttg tatcaataca catatggctc atcattccac
   149161 agattactag attagtaata ttttttttct caaggatact ttgcaaatct gtttcaaaga
   149221 aactatctgg tgtgtgttta attataattt cttcattatc tagtggaaaa acaattttat
   149281 ttatttctga accatgagta ttaggaagaa aaaaagaagc tgttttatct gttgatatat
   149341 gctgtatatg aataactggt aaattgtttt ttctaaaaaa cagtagtatt tttttagcat
   149401 tttcagcagt ttcttctgat tgaaataatt cacattttcc atttttaaaa taatcatttt
   149461 gaatatcaat caatattaaa gctatagaca tgattatacc tcctatttat ttttattata
   149521 atactattgt aaaaaatgta aattacttac tttttggtat gtataggatt acttattgta
   149581 gcaaattcct ttattatcta gaatttcttg ttgaccatgt tcaagcatat attcgattcc
   149641 tatttcttgc attatttcca ctgcttttaa cattttttta ccacgattag tgagaaaata
   149701 ttcaacatgt aatggatatc cagcagaact tattttatca ataatcccaa aatcacgtaa
   149761 ctcttttaat tgttgaatca acattttttg atttattcca taaatattat gttgcaattc
   149821 agaaaatgtt ttattagatt gtcttaattc aaatataagg atagttttcc attttccttt
   149881 gattatgtca tgtacaattt caagaggaca tgtatattca gctcttattt tcatagcata
   149941 tcacccccag taaaatgata ataaattata tcacttgtct tgtgatatga caaatatata
   150001 tgaactgtat ataaatttta tgttttatta agttctaaat ttcttctatt gtagttcata
   150061 tttagtacat aaataattag taagatataa gtaaataaat atataacatg actatagaaa
   150121 tttaacttta aaataactta tgataattta gaggaggaat atatatgaat atatcaagaa
   150181 aagctatgaa aataatagaa ttagcacaaa aaattgcaaa taagaggggt atttcagtag
   150241 aagaagcttg gagtgaagca gtaacagaat ataaaaataa atacgaacat attgcataga
   150301 tatttaaaaa tttagaatat ttggtagaat ataatgattt taaatgatac tataaattat
   150361 aaggtatatc attattaaca tagaaggagg atatctgctt gattgtaaaa atagataata
   150421 ctttagaaaa agaattttgg caatatgtat cacatgaaga aagtttaaat ttattcataa
   150481 ttggatatgt tgagaattat ggatttagct ctcaatatca agatatatgg tctcaggtag
   150541 aagatggaaa tataacctct ataatattaa aaaataagtc aacacttata atttatagtt
   150601 ttaaaaataa ttttaatata ggagaaatga agaatcatat aaaagattta gatgtagaaa
   150661 gcataagtgg aaaaaaatgt gtaatagata gactaataag taaatacaaa gatttttatg
   150721 aaaaactaga taataaattt tgtgtattaa aagaaataaa agaaatagat ttttccaaca
   150781 tgaaggagta taaaatagaa aatgctcagg aaaaagatat tgatgaaata ggaaaacttt
   150841 taaataggtc agactataaa gtaagtaaaa attacataga agaaagaaaa gttcatttaa
   150901 aagagggaaa tgtaagagca tattttatta gaaatgatga tactatgatt agcactgtgt
   150961 caactggtat ggaaactagt tttttggcaa tggtggtctc tgtaagtaca gataaaagat
   151021 ataggggaaa aggacttgca agttatatgg tttacaattt gagtaaagaa ttgttgttag
   151081 aaggaaaagt tccatgtctt ttttataata atgatgtagc aggtaaaata tatcataata
   151141 taggatacaa agagataaat gaatggacaa ttctttttaa atagctataa aaaataaaaa
   151201 actctatcga gaattaaagt atttataaat aactatattt ttactataat tcatgataga
   151261 gtttttttaa atttatgata ctatttttta ttatttaaat aatcaagtgt tttaagttta
   151321 taaccttctt tttcccaatg cgtaagaacc tcatctaata tctcagtatt tgttgatgaa
   151381 tttggatgca gtaaaactat tgcaccagga tgagttcttg aataaatttt gtttttggca
   151441 aattcatgag taggttgttt cttttcatac caatctacat aagcaaaact ccaaaatatt
   151501 gatttatatc ctaaatcttg tgtatatttt aaagattgtt cgctaaattt acccattgga
   151561 ggtctaaaat acttaggcat ttcttttcca gtaacatctt tgtatgcttt ttctacgctt
   151621 gtaatttctt ctttgaattt ttcaaaatct gtaatacctg ccattgatgg atggcttttt
   151681 gaatgattac aaactaaatg tccttctttt tccatacgct ttattaactc tggattgctt
   151741 tttatataac tttcaactac gaaaaattga gctttagcat tgtgtttttt aagcgtatct
   151801 aataattttg gagtgtttcc actttcatat ccagcatcaa atgatagata tataactttt
   151861 tcattgggat ttcctacata ataagctccg tattttttaa aaaaatcagc ttcttttata
   151921 ggtgatggct gtttaccatc ctccctaggg ttaaaatacc aatcatattc atgtgtgtcg
   151981 agtgttggac tagaaatttg agtttttgtt ttatctaatg atttaaaatt tatactagca
   152041 attccaaaaa gtattagagc aaatgctcct atcataatgt atttttttag gctatctttt
   152101 ttcacaattt cacctcttat ttaaaattta aagtatattt cctataatat agtttgaata
   152161 tttatagtta aaaatattca catatacaaa taataaatga aagaagtttg ctgtaagata
   152221 taaagttgat attaattatc ttaaataaag tgtatataaa tgataaaata taaagagaaa
   152281 tgattgtaaa taagttaggc tggtttaact tgaagggata taaaaatgga taatataata
   152341 agtgtattga atgatgttgt ttttttagat atagaagtta gtggattaga ttgtttaaat
   152401 tcagaaattt tagaagttgg agctgtcaag gttaaagact ggaaaatata tacctatgaa
   152461 tcattaataa aaaacaaatt tgaggtacct atagaagtat tctcagtatg taaaaattta
   152521 gataaaaatg atttagaaat agctaatgaa atagaactgg tggaagatag acttgtaaat
   152581 tttgtagaag atagtttcat tatatgtcat gatttaagtc tgaaaaaaaa gtttcttgag
   152641 tatcatatgc caaagttaaa aaacaaattt attgatttaa ttgaattagc agttatttta
   152701 gaaccatatc ataaagatta tagcttagaa tacttaaaaa atactttaac aaattgtaat
   152761 tctaaagtgg aaaatagagc tttatcagat gctattgata taataaatat tgtaaattgc
   152821 cttttagtaa aatttaataa ctatgaaaaa actactttgg agccattgag ttttaaaata
   152881 aattcatatc ttaaaaaatt taatcttcca acctgggaat ggagcaaatt tttagaagag
   152941 gcaaattatg atttatcaaa taatataaat ataaaaaaag aatataatat atttgactca
   153001 aaagaagaaa agaagaagga aagagaaacc ttaaaaattt taaatgaaga agaaaaaaat
   153061 tatgaagaat tattaaaata caaaactatt tgggagaata aagaaggatt tacatatgaa
   153121 tatagacctg gtcaatatga gcttactaaa acaataagag agttgtttag aaatagcgaa
   153181 gatgaagaaa aaattgcatg tatagaggca ccaactggta taggtaaaag tgtaggatat
   153241 ttattgcctg caatattaga ggctagaatt aataaaaaaa gattattaat ttctactgac
   153301 acaaaggaat tgcagataca attaataaat aaagatattc caaatgtgtt agattctttg
   153361 ggtctaaatg gaaaagtaag ttacggatat ataaagggaa aaaataacta tatttgtata
   153421 gatagactgg aagcatatat agatgattat gagtctcaaa accctactaa aggagaaatt
   153481 ttatctttaa tatttttgaa gagattagtt gaaggtggca agtatggaga tatagaagaa
   153541 ataaattatt tagtgtttga caacttcaag gaaataagta ctcacttaag aaatgtaagt
   153601 tgtgacccaa atatgtgcag acctaaaaaa tgcaaaaaag attgtttata taaaaacaga
   153661 atagaagaat taaaagaaga acatataaca gtagtaaatc attcactatt agctaaatgg
   153721 ccgtataagg atgaaaaacc tttagaaaat ataatagtag atgaagcaca taatttgact
   153781 gaaaaaggat atgatttctt ttcaagcatt ataaattcaa agtctttaag gtatttatta
   153841 caagaaattt atccttacga gtttattcaa aatagtagct ttatatataa aaaatatagt
   153901 agaaatatga gaaaaataaa ggcttttgat aaattttata atgtattaaa aattggaaga
   153961 gaagataaac aaaaaattgc tagaagcata aatctcatta ttgaagagat agattcaata
   154021 ttaaattttg gtaattgtaa tgaatataat aatgtaagta attataattt aagatgggaa
   154081 ctgaatttgc aaatagatga aattgtggga aaactaaaaa aggatggtat agatactgaa
   154141 ataagttata gagcctatag tgaaaagata aagttgagtt gtgagaaaat aataaaaaat
   154201 ttagtttcaa taataataat aatttatagg aatattgatg atgatagtat agataaagaa
   154261 gcagatatat ataaatttgg aaaggcaaag acaagagatt tagaggatat aaagattata
   154321 tttgaaatct ttttagagta tgatgaaaag gatgattatg caaggatagt tgaaattgat
   154381 aagaattata atgtctttga atttcgagta gtgccattaa aaatagcaga tttatttgaa
   154441 gaaaatattt tatctcaatt agaaaaagga atatttttat cagcaacttt gagtttatct
   154501 gaaagtatgt cttattttaa aaatacatta ggaatagaca gagttaagaa tgtggaaaag
   154561 attatagaac caatttttga ttataaaaat agagtctctg tagttggatt ttctgatatt
   154621 tgtgagtaca gaaattctga atttccaaat gagatgagta aaattatatc taatatatca
   154681 aagattacag aaggtcatac attagctctt tttaatagta aagatagaca agaaaaaact
   154741 tatgaaatat tgaaaaaata cttacatagt tttaacttag aaatttatgc tgataaaaag
   154801 gggattagac accttaacga tttaaataga aaatgtgtag tacttggctc aaaaggatgt
   154861 tttgaaggcg tagacattcc aggggatggt ttggtttgtg taactttaga caagcttccg
   154921 aatctaaatc ctaaagaccc tttgtatttt actataatga agaagtatgg tatagactac
   154981 tatactataa attatcctca aatgaccata aaggtaaagc aagctatggg gagaatttta
   155041 agaagcaaat atgactatgg atgttttgtg atttttgatg taggaactaa tataagtgtg
   155101 ttaaagagat tagagaaaga tttacacgat tgtaaaattt caaaggttaa tagcaatgag
   155161 ttttatactt atataaggcg acatttaaat aaatctagaa gtttaatact aaaatctgtt
   155221 atatttgata ctataaaagc gttgaatgtt gatgctaaaa tggataacaa tgatgttgat
   155281 aaggatatta taaaaaaaga tataaatgaa aatataagac aaagagctgt aaaaggagaa
   155341 gtgtaccata ttgatattat aaaaaaagat atgaaagtaa aatattttga tagaaactat
   155401 cttataaatt tagatatatt tatgagagaa gaagataaaa attaagagtg ggagtgatat
   155461 atttggcaaa acaaaagttt tatgctgtga aaaaaggtaa aaatataggt gtatataata
   155521 catgggatga gtgcaaaaaa caagtaaatg gattctcagg agctgaatat aagagttttt
   155581 ctacttttca agaagctaaa gaatatattg atgggtcaga aaaattgagt tttcaagaag
   155641 ataaggagtt tatagaagca tatgtagatg gaagttatga acattcagta aaaatgtatg
   155701 gttcgggtgt tgtgatttta aaaaataatg aagttataaa aacttatagt gaaaaaggaa
   155761 aagagaaaac tttagtaagt atgagaaatg tagctggaga gatagaggct tctaaaattg
   155821 caatgcagta ctgtattgac aataatgttc aaaacttgat tttatacttt gactatgaag
   155881 ggattgaaaa gtggtgtact ggagtttgga aaacaaataa agaaggaact atagcatata
   155941 aaaatttcta tgacagtatt aagaataagc ttaatgtaaa atttacaaag gttaaagctc
   156001 attctggaaa taagtataat gaggaagctg ataaattagc taaaaaagct attggtgtat
   156061 aataaaaaaa tatttataca taattacatg gtataagagt atatctaaat tcctacttta
   156121 taattaaaca acttgtaatt aaataaattt tgattaaata aattttgatt aaaaaagcag
   156181 attgtattat gaaaaaataa gtatctaatt tataaacaat taataatagt attaattaga
   156241 tacaacttat ttaatataat aaaatctgct ttttatataa ctataaaatt ttactacatt
   156301 ctattagaat tgcccataaa taccttcaag ttcttctttt aatacttcag ggtcatttat
   156361 accaatagac atggttctag ccagtatatt tgcttggtca taagttgatg tccatgagaa
   156421 tacaccacct agacaatttc taagaacata ttgagttttt aagaatattg ataaagcatc
   156481 atcatatgac attgcaaaat ctccatcctt aactaaatac ggaacttgag cagtattatc
   156541 aaatctatat tcatatccat ttttatttat ataatccctt ctaagctcat cataagttct
   156601 tgttatagta gcacctaatc ttccataaaa tggtatacca agaaggattt tttcagaagg
   156661 cattccagca ttctcaagat ttctcaccat tgcatcaaca ctatatcctg gcaaagataa
   156721 gtctgaatca aaaagatttg cttgatgttt tctaccattt gggcctgttt cacctgctgt
   156781 aaaatcataa ctcataagat taaaataatc tattatagga gctattttat ctatttcagc
   156841 acttgaattt atatatcctc tatctcctgt tccagctaca ctaagccatt tatcatctcc
   156901 tataacatct cttatggcag ttagtaagag tgtaaaattt tctctatctt gaggtcttga
   156961 tgttattcca gatgcactac ttccaggata ttcccagtct atatctattc catctaaagc
   157021 atattcattt atcatctgat tgacctgtct tgcaaaatta tatctagatg taggtgttaa
   157081 tgctgcatca gagaatcctt cagctcccca acctccaata gctacaatta cttttaagct
   157141 aggtttttca cctttaagag caagtaattg atttaaaaat ctaggataag gaataaacaa
   157201 atttccagac tggtctatct cagcaaaagc aaatataact gcatctaata gttgagcatc
   157261 tacattagtt ggatttccaa gaacatattc tgctacaatt ggatttatat ctggacagtt
   157321 tgcattttca actattggat tgtatgggtc tgttatttgt ggtctaacta atttttttga
   157381 atcttttaaa gttttcatag ctattttttt agtatttttt tcgctagtat aatcgtagtt
   157441 tttataatta tgtttataga aatcttcata actactatct tctttgttat agctagaatt
   157501 tattttgtcg caagattcat ctttgtcata gttaaaattc atttcatcac aagacttatc
   157561 tttaaactta tcttgtttgg agttgtgaac tttgttagta tttttagtat gttttttctc
   157621 atgattgcaa tcatctttaa tatcagtctt gtgttcttgt ttacaatcaa gagctttgtt
   157681 caggtagtca tgatgttcat gttcacagtt acattcattt tcaatgtttt tagtatgttc
   157741 ttttttccag ctacaagtat tatcaatttt cttgctcact tcttcatcat tataattatc
   157801 tggtacaaaa cataagtacc agtccataca tgagtatttc ttattacaac tgttaactct
   157861 attttttaat tccttatagt ttttaggata aggtaaaatc actggcattc caggaaacca
   157921 gtttgcagga gtaactatat tatctctatc actagtctga agtgcatcta ctattctaag
   157981 tatttctgga atatttcttc ctgtagttag cggataataa agaatcgttc ttagaatttg
   158041 attattatct ataataaata cagagcgaac agttgatgta tcactcattg gttttgatat
   158101 catgccgtat aacttggcaa ttctcatatc tctatcttct ataataggaa atggaatttc
   158161 tacacctgta agtaaagaaa tattatacat ccaagctaaa tgtgaactgt tactatcaac
   158221 acttagacca attagttctg tatttctttt tttaaattcg tcataatatt tagcaaaaca
   158281 taaaaattct gtagtacaaa ctggtgtaaa atcaccagga tgtgaaaata aaacaatcca
   158341 attaccctta tagtcagaga gtctaatagg accatttgtt gtattggctt taaaatcagg
   158401 agcctttgac cctaaacttg gcaaatttgg catgtaaatc acccctcaat aaattatcat
   158461 ttattttatt ctattaatta atacatatta gtgttactat tttattaaaa gttaagtaat
   158521 ccttatgtca aaaaaagata tttattaaaa agatttaata ttttcctaat ataaatgaca
   158581 atagtaattg ctattttttt actaatttgg tatagtaatg gataaggggt agtgtcaatt
   158641 ttagtgatta tacgaggtga gtggattgaa aaaaattcta agaattttag ttatctccat
   158701 gatgatatgt tttgcaatga cttttgcatt agtgttaata aattcagtta tgggagtaca
   158761 tataggattg gattattact ttttgatggg aagtgtgctt acagtttgtt taacaattgg
   158821 aattgtttta tgcaatgcta gaaaaatatt tgatagcaaa gctatacaca agacaagaac
   158881 gaaaactgtc agtaataata aaaaacaaaa gagtcattct agggatataa aaagaaagat
   158941 atcataattt atgtaaagga aatatttatg tataaaataa tgattgatag gtaaaataaa
   159001 aacacgattt aacttgtgtt tttatttttt ttcaagaatt atgatataat aaccaataag
   159061 aaatttagtt taccataaaa tataaagatt attaaatgga gagggaacta taatgaattt
   159121 tagagattta tttgagaagg ctatagattt tattgatgaa aaaaggaaat ctatagttgc
   159181 gatttcatta tcaacattag gtgtaattgc tttgataata gtatttttct taagtagtaa
   159241 cgagtttagt gtaggaaatg aagctaatga gttgttaaag attatagaga aaagacagta
   159301 ttctatagct gttgattact acacaagtat agaaaaaaag ttttctgatt caaaaatgga
   159361 aaggtttaat aagtctgttt ctaaaaaaat aaataaattg ctattaaata gtggtgataa
   159421 atatttagat ggagacataa gtcaagaaag ttttattgga ttaataaata ccgtgaaaga
   159481 attaaacaaa ataagtatag atgtggatga cttattagtt caagctgata gagttagaga
   159541 aatgtataaa gaagaaaata ctacttatga tattgccatt aactacataa gtactgtttc
   159601 aatattaaat ggaatgggta gtaacctaga tgtatacaaa cagaatatag aaacaatcaa
   159661 agagtctaga gatgtttatg actcagcagt aaaagaccaa aaagcatata agtattatga
   159721 agctattgaa aaatataata aagtattaaa agaagatgaa aaatattaca gtatggctca
   159781 aaatgggaaa gaacaatgta ttgaagaaat gtatgattac tatataagta gagctgaaga
   159841 ggcaaatact tctggagatt atgaaagagc attacaatat attgagtatt taaaagaaga
   159901 ttattcagat gatgaaaagg tacagagttt agaaaaaaaa tataaaaaga atttatcatt
   159961 gtatacttta acatctgatg acattataaa tgtaatagct aaaaaaagtg gcaaagacaa
   160021 ggcaaatcta tctataaact cacttccaca aatgataaaa aataataaat actattatgc
   160081 tgaagtatat gagtatgata aattaataaa tgaagttttg gtaagtgcaa aaactaaaga
   160141 tttatattca tataaagatg gtaaaaaaga ttacaaagta gattatggtg atggatactt
   160201 tagaatatta gaagatggaa gttatcaatt tggtattaca aaagataaag ctaagtttgt
   160261 gttaactaat actcttgatg aaaaagaaaa taagtataaa aagattgata tattagatat
   160321 agagaaagca gatagatatg taaaaagtaa aaagagttta gaagaattgt ttggaaaata
   160381 taaaaatatt tattattatg ctgtagtaaa taaaggctta tttagaggca aagaagttta
   160441 tgctattaat atttacaatg aaaaaatata tgccatatca gaaaatggac taaatgaata
   160501 ttaattaata atattaaatt aatatataat taaaaagttt ttggggtttt aaggcgcatt
   160561 atgtagtaat ataataatag ggatatataa ataattttat tgtaaggaga agtatgggat
   160621 gagtaatgtg aacaaaaagc tagttatagc tattggagct gtagcattag tagtaataat
   160681 ttttataggc ataatgtgca tgcaatttaa aggggagaaa atagcaaaaa acacatatgt
   160741 taatggagta aatattggaa aattaactaa atcacaagca aaacaggaat tagctaaaaa
   160801 atacaaatta gagaatgttg attttaatta caatgataaa agttggaaag taaagagcaa
   160861 agatttaaat ttatctactg acctggataa aacagtagaa aacgcatata atttaaatag
   160921 aaagagtgct ttctttggca atctatcaaa aactatttca gcaaattttg gcaaaaaaag
   160981 caacttagta gttgtgataa attatgataa aaataaatta aaagcagaaa tggaaaagat
   161041 agctaaagaa atagatgtag atgtaaaaga tgctacactt gatataagtg gtgaaaaagt
   161101 caaggttata ccagattctg atggtcttaa aatggatatt tctaagagta tggagaattt
   161161 tgataatcaa actaaaaaag gtaactataa aaatgagtta gtagtaaaag ctactccagc
   161221 aaaagtaaaa aaagagcaac ttgctaatat agatacaaat ttaggtacgt attcaacaac
   161281 atttaaaact tctcaaataa atagaagtat aaacataaaa ttagcaacag ataatataag
   161341 taatgtatta cttatgccag gagaaacttt ctcatttaat aaacatacag ggaaaagaag
   161401 taaggaaaat ggatataaaa gtgcacctgt aataatggaa ggtgagatgg aagaagatta
   161461 tggtggagga gtttgtcaag tttcatctac gttatacaat tctgtgctat acgcaggttt
   161521 agaaattgtt aatgtaaaaa atcatactat accatcaagt tatgttccaa aaggaagaga
   161581 tgcaactgtt gcagatagtg gaatagattt cttatttaaa aataatctaa agcatccagt
   161641 ttacataaaa aattacgttt caggaaatca aattgtttgc aatatatatg gaagtgcaga
   161701 agataaacaa aatataacaa tatcaacaaa attagatggc gtttcacaaa ctacaatgaa
   161761 aagagttaat gaccctacaa tgcctaaagg taaagaaaaa gtagacaaaa gtggaagaaa
   161821 tgcatattct gtatcaacat atagaacatt taatgatgca aatggtaaaa aaattaaaac
   161881 tgaaaaaata gctaattcat attatcctaa gaaggaaggt attatattag ttgggactat
   161941 ggaaccaaaa ccagaggaaa aaccaaatac agacgaaaat aagaataatc aaaatacaaa
   162001 caatcaaaat ccaaataatc aacaaaaacc agaaacacca ccaactgata ataagcctaa
   162061 tgagacacaa ccacaaccgc aagcttaaag ttctcaagaa taggatttat gtagagtaat
   162121 aaaaaatata aatctaaata ggagggatta ctttgaattt aaataatata acgaattacg
   162181 ttcaaagtat ttgcgagaat atttctaatg tcttggatgt agatgttact ttagttacaa
   162241 aagatttaac taggatagca ggtacaggaa tattcagagg taaaatagga gagacaatat
   162301 cagagaagtc agtgtactct cttgttttaa aagatggaaa atcctatgtt ataaataaag
   162361 aaatagaaga gaactgtaat aaatgtgcaa atagagaaaa ttgtaaagag ttagctgata
   162421 tatgcactcc cgttaaaatg ggagagcata tacttggaat cttgggtata gctgcgttta
   162481 atgaagaaca aaaagaaaag atactttcaa aagataagga gttaactgct tttgtaagga
   162541 gtatgtctga tttaatatct tttaaactag atgaacttta taaacaagaa gttaagacta
   162601 tagatgacct tgagagggaa gctatagaaa atgctataaa gaaatatgga agtaatacag
   162661 aaggtatgaa aaaagtagct gaggcattaa atataggtat agctacactc tatagaaaag
   162721 taaaaaagtt caacattaaa agttaatagt attgaaaaag aggtaacctt tttatgaaaa
   162781 gaagaggatt acctttttta ttatgagaat ggtggaaaaa tatgtatagt tttgacttga
   162841 catattaaat atgttatctt aaatatatat tttagagtgg aggtgagtat tattttagtt
   162901 aaagatataa aacaagacat agaaagcatg cctagaaaaa ttttagatat atctttgata
   162961 gaagataata aaagtgattt gacttttttt aatatagaag aagaagacgg tgatgaaaca
   163021 ttaaaagcat taaaacagag ttatgtgact acaaattata aagaagaaac tctattaaac
   163081 ttgcaaggag ctttaaattc aaagtcagat acaacgtcta aggagttaaa attagaatca
   163141 tataaaagat ataacaatgc attggattta gcatataaaa attatataac tagtgccatt
   163201 aatatggtta ataaagctct ggagataaat cctaaagaca ttgatatact aaatcttaga
   163261 ggtcttttaa aattattaaa atgtgatttt gctaaatcat ttgagagttt ttatactgct
   163321 ttatgttatg aaaataatca tatatctaga aaatatgtaa atctaatttc atctgaagat
   163381 tttaaaactt ttttaggaag atacaatcat tctataagat ttataaatga agaattaaat
   163441 tatgagtcaa tacatatttt agagaacata attgaagaag aacctgaact aatagagcca
   163501 tatgtaattt tatctttgtt atatgataaa ctaggtaatg taaaaaagag agaaggatat
   163561 ttagacaaac ttaaagagct agataaagat aatcctgtat ttgaaaaaaa tgaagaagaa
   163621 aaagaagata caagtaaaaa ggaagaaata aaaaaagtaa aaagaaagaa aagtattttg
   163681 ccatatatta tagttggctg tgttttaata ggtatgggga tatatttgat tcaaagcaaa
   163741 aagagaatag aaaacttgaa taaccaaata agtagtaaag aggaaaagtt aagtgaaact
   163801 gataaaaagt taggagaaac gagtaaaaaa ttagaaaaaa cgaataagga attaaatgag
   163861 gttaaaaata aagaaccaga aagagagata actgtagctg atgaggaaga tttatattat
   163921 caagctctaa atttaaagaa aaacaaagaa tatgaaaaag ccatagataa ttttaaaagt
   163981 gtagtttctt ctggtaaaac taaaaaatat atttctgagt caatatatca attagcaata
   164041 acaaataaat tattaggaaa taaggatgaa gctataaaat attacaaaaa atatataaat
   164101 acttatacta aaaatgacca gtattatgat gattcatatt acgagttggg tatgctttat
   164161 tatgataatg gcgatttaaa aaatgcacaa cagacttttt atagtttgag aagtgaagtt
   164221 ccagacagta tgtataacaa ttcaaaaata aaagaaattt taagtgaaaa ataggtttat
   164281 atagttaagt tttttgaaac aaccaagtat gtattttatt aaattaaaat aaaaataaat
   164341 ttaaaaagag attgtgtcaa attataactt tctattttaa agaaagatat ttgcttgttg
   164401 ataaaactac aaatatatga tttgaagcaa tctctttaat ttttggaggt ggaaaatgaa
   164461 agttttcaat caattagtaa taattttatc tatctgggta ataggagagt atataagttc
   164521 ctttatacaa ggaattatac ttattcctgg gagtatagtt ggtatgctat tattatttct
   164581 actactacaa tttaaagttt tagacttgag tagtatagaa aatgtaagtg gatttttcct
   164641 cgataatatg gctatatttt ttattccagc aggtgtatca cttataaagt cattagacct
   164701 aataagggaa aatgtattag tgcttttatt agtcatatgt ttaagtacac taatagtaat
   164761 gtatactact ggaattattg tggagaaaat gataaaaaag aaggaagaag gacaaaaaaa
   164821 tgtataatgt attacagaca ccagtatttg gtataatagt aacaatagtt tttttcaatt
   164881 taggaagata cattcaacga aaaacaagta atcctatatg taacccttta ttaattgcaa
   164941 tcgtaggaat aatattgttt ttaagcatat ctaaaatccc ttatgagaat tacaagatag
   165001 gagctgatag tctaaatttc tttttaggtc ctgtcacagt agtacttgca gttccacttt
   165061 ataaacaatt tgaattattt aaaaagcata tgtttgagat tattgtagga ataggttgtg
   165121 gtatagtgat ttcttttgta tctgtattga taattggcaa aatagctaat tcagatgtaa
   165181 gtataataaa ttcactaatt ccaaaatcta taacaacacc aatgggaata tctttagcaa
   165241 attctttaaa tggtatagaa tcaataacag ttgtagccat aatttttaca ggtatttttg
   165301 gtggtatggt tgcttctaca gtattcaaac tggggaatat aaatcatcca gttgctaaag
   165361 gaattgctct tggaacatct gcacatgctt taggaactac aaaggctttt gaacttggag
   165421 aaatagaagg agctatgagt ggtgtttcta ttggagtctc tggtacaatt acagtaatac
   165481 taattccaat tataatgaat tttatataaa aaataaaatt aagatgagta ccttgaatac
   165541 ttaaaacaaa ataaaataaa aaaaatttaa aataaaaact gaacgaaaaa aatgcaaata
   165601 atgaaataaa aaaatcatgt actgaaatta taaaaagaaa aatttcattt aggaattaat
   165661 tataaagaga caattactaa acttgaattt gctaaaataa aataaattac tgcgaaaata
   165721 gatatttaga aaaaaatact ataaatttac tatattgcaa gttaaataat aagcagtatc
   165781 atattatgct agaaaaagtt tcatttaagg cataaatgag atgatttgaa cgtttttaaa
   165841 gattagaata taaaagattg cactagacat atatgaaaaa gataatataa tagatgatgt
   165901 aatagatgac agttcaagaa attataaaaa aaatttattt gaaatattat ctattacatc
   165961 aggaataata tatgtaagag taagctttta aaattctaaa gatttagaaa gattgaaggg
   166021 agaaagaaat gagtgaagtt aagaataccc tacaaaaaca tccagtttta agatattcaa
   166081 caatgctatt tgggatgttg atgacatcta taggaataaa tgggttctta agaccagcac
   166141 atctacttag tggaggtgct acaggtatag caacatctat aaactatttg acaaatataa
   166201 atgtaggttt attaacattt ttaatcaata ttccaatatt tatcttaggg ttcatatacc
   166261 ttgaaaaaga gttttgtatt tcaagtttgg taaatatgat tgtattttca ttattattag
   166321 gagcaactca ggaaataagt aatattatac ctatacatga tatattgctt caaagtgtat
   166381 atggtggtat attatctggt ttaggagtcg gagttgtatt tagaactagg tcttctcaag
   166441 gtggtacaga tataatagct gcaatactaa aaattaagaa gaatatagaa atgaaagaca
   166501 ctgctttagc aataaatggc ttgatagtac ttacaggaag ttttttattt gggttggatt
   166561 tagcattata cactcttata ggtctatttc taaatgcgta ttcaatgagt tttattaaag
   166621 atgcaatgaa ttaccaaaaa tctgttatgg taatgtcaaa tgaagtcgat ttaatagcag
   166681 aagatataat gaagagttta gttagaggtg taactttttt agatgcagaa ggtgcataca
   166741 ctcatcaaaa aaagaagatt atatatacaa tagtttcatc aaatgagata ccaaagataa
   166801 aagatatagc tttgaagtat gataaaaagg cctttatatc tgtaaatgat gttacagaag
   166861 taaaaggaag agggtttaaa gcaaaagatt tatagaaaat tttacaagct gggagtttat
   166921 aatgtaaatt tgtatattat atctctcagc ttatttaaat ttagtatacg aaaataaagg
   166981 ttttattaat gatttgtgta tcactttaaa agatatcatt ttaaaattaa aattgaaaaa
   167041 attacttaat atgtagaaaa catgaccact attaggatat aataaattta atagatttag
   167101 taaaatatct aggaataacg ttggaggaat ggcattatga atttatctaa agaatatgtt
   167161 aatttgtatg ataattattt gaaatatata aatgaagtaa acaaagagat tagaagtata
   167221 aagaacatga agaaacgtgt tttaaaaagg ggcgattttg ctccggaaaa tgaagtatta
   167281 gaattggaag gaaaaacaat acgcgatata gatgatgtcg atacaaaaaa accaaaaaat
   167341 aaaatctata aattttcaaa tggggatgta tatgtaggga aattcttaga gggaaagatg
   167401 gaggggaaag gctcatatac tttttttgta gatgaaggaa cagttatgga gtacatagga
   167461 gaatttaaag aagataaaaa aaatggaaaa ggaaacttta tattttcaaa tggaaatgaa
   167521 tatataggtt attttgagga agatatgatg agcggtattg gaaatatgtt atatagtagt
   167581 aaagatgaat atattggaac ttggaaaaat ggaaaaaaag atggaaaagg tatttataag
   167641 tggagtgatg gatgtatata tgcaggtgaa tttaaaggtg gaaagatgga agggtacggt
   167701 atttgctata atagtaaagg ggaagtactt tatgaaggag aatggaagaa taatttgatt
   167761 catggtaagg gaacttatat atgggaaaaa ggtaaaaagt atataggtga atttatgcat
   167821 ggtaaaaaac atgggcaagg aactttttat ctaaataatg aattggttta tgaagggact
   167881 tggaaatttg ataagccatc tatatttgat agaacattag atgaaatatt ttccttgaga
   167941 ctgtagcttt atctaattag tagataaagc ttttttctaa tacttactgt aaataggtat
   168001 gaatgatatt gattagtata cactatcaat attaacttaa taaatgcaat attaaaaaat
   168061 tttgattgat tttaagaagg agagatatat tgaagagatt aattgcttta gtgttagtag
   168121 tacttattgt tttattttat agtcctgaat tattaaaaga aggatatgat ttaaaagaaa
   168181 agttttttca aagtgaaata tggaatgaac ttttagacaa aataaatata aatgataatt
   168241 ctaagaaaga taaaaaagaa aaaagtcaaa atttacaatc aaataatact gaaggggaga
   168301 acttaggaga gtcagatata aagaattttg aaaaaataag cttaggagat aatttaagct
   168361 atgttttatc aagtatcggc aaacctggta gaattgatat tagtgaatat ggttttgatt
   168421 ggtatgtata taatcaatat ggaaaagaat ttgcaatggt tggacttgaa aatgatgaag
   168481 tagtagcact ttatagtaat tctattaatt catgtgaaaa tcaagatata aaactaaatc
   168541 aagatagaca aacagtgaga actaagatta caccattaaa atataagaga aaaggaaata
   168601 ccagatatat aataaactca gaaaatcaat atgatataat aagtaaggaa ggtaagtata
   168661 ttacaatttt ctacgatatt catgaagaaa atagagtttg ttcatattta ataattgata
   168721 aaagcactga agatgagttt gaaaatttat atccagatga tagcgaagaa cttaaaaaat
   168781 gttttgaact tgaagttata gacattgtaa atagtgttag aaatcaaaga gggttaaact
   168841 cattgagata cagtgaacag gcaactttga gttcaagaaa acatagtgaa gatatgagag
   168901 ataataattt ttttgaccat gtaaataaga agaatgaaac tccatttgac agaatgaaaa
   168961 gagaaggtat agtatatact tcagctggag aaaacatagc agcaggacag attaatgcaa
   169021 tatatgcgca tgaagcttgg atgaactctg aaggacatag aaaaaatatt ttggggaact
   169081 ataataatat tggagttgga gtaatatttg gaggaagcta taaaacatat tacactcaaa
   169141 atttttataa ataactaaaa tatttgaaag gaagttaaaa aatgacatca tggaaaaaaa
   169201 agacagtata taagtgctta atagcagtag tcttgttttg tggaatagtg ttaatatcta
   169261 attttagtaa agtttctgct ttgatgatgg atactaatgg aaatgttttg attaaacatg
   169321 gttcaaggga aaaaaagcta atagcaatta cctttgatga tggtcctcat cctaaagaaa
   169381 ctagtcaagt tttagatgta ttaaagaaat acaatgtaaa agctactttt tttatagctg
   169441 gaaaacatgc aaaatggtat aaagaaccat tagtaagagc aagtaaagaa ggtcacgaga
   169501 taggaaatca tactttcaat catcctgata taagtaattt aagttctagt cagatagaag
   169561 aggagattgt taagtgtgaa gacattttga aagaagtaac tggaaaaaaa ccgacattat
   169621 ttagaccacc atttggaagt tatagagaaa aagaattaat agaaattgca aaaaagcatg
   169681 actataaagt tgttttatgg acaggtgtag atgtgaaaga ttggaaaaat ccaggagcta
   169741 atagcattgc agataaaata attaataaag tacaaaatgg agatataata cttttgcatg
   169801 attatgcaac taatgataca gttgaagctt tagatatgtt tattccaaaa atgattgaaa
   169861 aaggttttaa atttgtaacc gtttctgagt tgataaaata atttttaggg gggagattta
   169921 cagtatgatt cttatgatag acaattatga ttcttttgta tacaacctag tccaatatat
   169981 agaagaatta ggagaaacag ttgtagtaaa aagaaataat gaaatcaaaa taagtgacat
   170041 tgaagaacta aatccagagg taattgtgtt atctccagga ccgtgttctc caaaagaagc
   170101 tggtatttgc atagatattg ttgagcattt taaggggaaa aaacctatac taggaatttg
   170161 tttaggtcac caaactattg gacatgtttt tggaggagat attataaaag cacaacagcc
   170221 tgtgcatgga aaagtatata gtatcaacca tactaataaa ggagttttta ggggacttaa
   170281 aaatccttta aatgtcacta ggtatcattc actaatagtt gactccaata cagttccaaa
   170341 agaattagaa attacagcaa ttactgataa aggggaaata atggggatta ggcataagaa
   170401 atatttaata gaaggagtac agtttcatcc agaagctatt ttgtcagagt atggtcatga
   170461 aatgcttaaa aattttataa cagaagctag agaaagggta catatgtaat atgataagag
   170521 agataaatac taaattaaat tcttttgaga tatttactat ttttagaaat gaacatgaca
   170581 gttttatatt agacagtgct atggataaag aaaaattggg aagatattct tttataagta
   170641 gccaaccatt taaggtatta aagtataaag atactgatga aaatccttta gaagttttaa
   170701 aagaagaact acataagtat agggttgtaa atgatactaa tcttccattt gtaggaggtg
   170761 ctgtgggata tttatcttat gatttaggta attacataga gaatttacct agaactgctg
   170821 tagatgatat tgagatgcct gatatgtatt ttggatttta taatcatgta atagttatag
   170881 accatcttgt gcaaaaaact tatatagcta ctccaaacat agatatcgaa ttagaagaaa
   170941 agataataga tgatatagaa caaagaatat taaaagaaga gaaaaaaggt atagatagca
   171001 tatgttatga agaaaaagaa gtaacaccta taagacttaa atctaatttt acaaaggaag
   171061 aatttaaaaa tgcagttcaa agtgttagag agtacataag acaaggagat atatatcaag
   171121 ctaatttaac acaaaggttc agtggagaaa cagaacttac aagctttgaa ttgtatagag
   171181 acttaagaag atttagccca gcaccatttg gggcattctt aaactttgaa gatgcacata
   171241 tattatcaaa ttctccagaa agatttataa gatgtgttaa taagagaata gaaactagac
   171301 caataaaagg tactcgtcca agagggaaag ataaagaaga agatttaaga cttcaacaag
   171361 aacttagaaa tagtgaaaaa gatagagctg aactacttat gatagtagat ttagaaagaa
   171421 atgatattgg gagaatatct aaaactggaa gtgttaaagt tccagagcta tttgtaattg
   171481 aaccatatgc aaatgtaaat cacttagttt ccacagttgt aggtgagtta aaagatgata
   171541 aagatgctac tgatgtaata aaagcaactt ttccaggggg gtctataaca ggagcaccta
   171601 agattagagc aatggaaatt atagacgaat tagagccaac gcaaagaaat gtatatactg
   171661 gttcaatagg ttatataggt tttaatggtg atatggattt taatatagca attagaacaa
   171721 taatcaaaaa tgacaaaaaa gtctactttc aagttggagg aggaatgact tgggattctg
   171781 acccagatga agaatatcaa gaaacacttg ataaagctaa atccataatg aaggctttga
   171841 ggggatatta tgaagaataa tgtaggtttt gatagtagtt taagtaaatt tggaattggt
   171901 ttgtttgaaa ctattagagt taaaaatgga atagcagtag atttagatat ccatatagaa
   171961 agaatgctaa gctcaataaa ttgtttggat ttagatataa actataaaaa agatttcttg
   172021 ataaatgaaa ttgttacata tataaaaaaa gaaaatgtca ttaataaagc acttagaatt
   172081 actgtttttg atgaaggtta taatatatct attagggata ttccatataa tcaagagacg
   172141 tatgagaagg ggtttaaatt agctatatct ccaatagtta gggggaatag tttaattcat
   172201 agacataaga ctactaatta ttttgaaaac atatatacca aaaatatcgc aaataagact
   172261 ggttataatg atggtatatt tttaaattca gaaggtgtaa tattagaatg ttctatgagc
   172321 aatattttct ttataaaagg agaaagagtg tacactccta gtgatagatt accgatatta
   172381 aatggaataa taaaaaaaag gattatagag atttgtgacg aattacatat agagttgata
   172441 gaaaatgaaa ttaatatatc agaaattagt agttttgatt ttgtttttgt cacaaatagt
   172501 cttatgggcg ctataaaggt tacagaaatt gacaaaataa aatttaataa agaaaatgtt
   172561 gtttttgata aaatagtgaa gttattagaa taaattaaaa tattaacaat ttgttggaga
   172621 caaaagatga taggttgtat ttatgaagta tacaatgaag agatgactaa aataatagaa
   172681 aaccaaaata ctttggctgt atatttagtg ggttctagta aagacgtaga ttttactctt
   172741 tatgatgtag aaataaacga tattgatgtg ttcgtttttg taaaagaagg ggaaaaacaa
   172801 gagagaatac tgtttaaaaa aaagggaata gaatttgatg taaattactt ttcaaaagat
   172861 ggtgtaaaaa aattattatc aaatagggaa tatttctttg tgaaagaaat gaaagatgct
   172921 aaagtactgt ttgataggga gaatatatca catattataa aagatataag tagaaatatt
   172981 tacttagaag gacccagtaa aatgtcatta gaggaaaagt cttttataaa gcaagatatt
   173041 ggagcaaaaa tatcgaattt aaaaaataaa gaaaaatttg atgtttttga atatcatttt
   173101 ttgacgaatt tatatttaaa agatataata attgggtact ttaatataaa tgataaatgg
   173161 gtaccaaaag acaaaaaatt gctaaaagtt ttaaaaaaag aaaataatga gctttttgaa
   173221 ctagtgtcaa aagtaagtga aaattatgac tatcaaagac ttttagatgt ttataattat
   173281 atttttaaag aaattgagac aaaagaggtt ataaaactaa tcttctagtc acaaatcaat
   173341 ggggggagtt taaatgaata aagttgataa agaaaagata caacatgcag taagagaaat
   173401 actagaggca attggggaag acccagatag agaaggtcta atcgagactc caaatagagt
   173461 tgctaggatg tatgaagaga tattctctgg tcttagtgaa gaaccaagag accatttaaa
   173521 agttcttttt gcagatgaaa aacatgaaga gttagtattg gtaaaagata ttccatttta
   173581 ttcatgttgt gagcatcatc tagttccttt ctttggaaaa gctcatattg cttatttacc
   173641 aaaaggagga agacttacag ggctttctaa acttgctaga gtaatagata cattggcaaa
   173701 aagaccacaa ttacaagaaa gaatcactaa aaatgctgca gatataataa tggaagaatt
   173761 acaaccttat ggtgtcttag tagtagtaga agctgaacat atgtgcatga caatgagagg
   173821 cgtaaaaaaa ccaggttcaa aaactgttac atcagcagtg agaggaatat ttgaaaagga
   173881 cattgcgtct agagccgagg ctatgagttt gattactatg aagtagcaat ttattataga
   173941 tataatcatt tattgagata aaatttaatt taagggagtg tcattaattg tgtttgatta
   174001 tggtaaaaga acttatataa tgggaatatt aaatgtaact ccagatagtt tttctgatgg
   174061 aggagatttt aataacttgg acatagcaat acaacatgca aaagatatgg ttgaccaagg
   174121 tgcagatata atagacctag gaggagagtc tacacgccca ggtcatagct atgtagactc
   174181 agacgaagag ctaagaagag taatccctgt aataaaaaaa cttaaacaag aattagatgt
   174241 accaatatca gtagatactt ataaggcaga tgttgcagaa gaagcattaa aattaggtgt
   174301 cactatggta aatgatgttt ggggtcttag aaaagataaa aatatggctt ctgtaatagg
   174361 aaaatatgat gcagaagtgt gtataatgca taatcaagat gggacaaact atgacaaaga
   174421 tataatggag tcaataaaag acttttttaa ggtaagtata gaaatggcaa tgagttgtgg
   174481 tgtaaaaaaa gaaaaaatag tacttgaccc aggtgtagga tttggcaagg attttgaaca
   174541 aaatattgaa gtattgagaa gattaaatga attaaaagat ttagggtatc ctattttgct
   174601 tgggacatcc agaaaatcag taataggaaa agtacttcca gttgagccta aaaaaagatt
   174661 agaaggtaca atagctacta ctgttcttgg tataagagat ggcgtagata tagttagagt
   174721 acatgatgtt tatgaaaatt taatggcagc tagaatgact gatgcaatat atagaaagta
   174781 ggtataatat aatggataaa atattactta gtaatctagg attctatgga tatcatggtg
   174841 ttcttaaaga agaaaatttt ctaggtcaga aattctttgt cgacatggaa ctttatattg
   174901 attcaagaga agcaggtctt agtgacgata taaataaatc tgtaagctat gccgaggttt
   174961 acaatgttgt taaagatatt actgaaaata aacaatttaa tcttttggag gctttagcag
   175021 aaaatattgc tgaagaagtc ttgaataaat ttatacttat aaatggagtt atggtcagag
   175081 ttagaaagcc tgaggctcct gtaaatggta tttatgacta ttttggtgtt gagataagga
   175141 gagcaagaga tgaataaggc ttatttggga ataggtacta acatgggtga tagatttgat
   175201 aatttatcaa gagcatgtga acttttgaaa aatagtgatt ctatatataa agtaaaagaa
   175261 tcaagcttat acgaaacaaa accatgggga tatacagaac aagcagattt tctaaatatg
   175321 tgtgtagaaa tagaaacaga gtttgaacct tatgagttgt tagaatattg tcaagaaata
   175381 gagagagaac tacacagaga gagaatagtt cattggggac caagaactat agatgtagac
   175441 atactatttt ttaatgatgt agtttccact gatgaaagac taacaatacc tcatccaagg
   175501 attcaagata gagctttcgt tttgatacca cttatggatt taaatgaaga acttataata
   175561 aatgaaaaaa caataaaaga acatttaaac ctcctatctg ctgaagaaag agaagaagta
   175621 aaggagcttg taggttatga aagaaaacct atttaataat aattcaaaga tagagataaa
   175681 tacaaataac aaaaagataa ctgtaaaaaa agataaactt ataatagctg gaccatgcgc
   175741 aatagagagt tatgagcaac ttttggagac tgctaaattt gtaaaaagtc agggagcaaa
   175801 cattttaaga ggtggagcat acaagccaag aacatcgcca aattcatttc aaggattaaa
   175861 aaaagaaggt cttgaaatat taaaagcggt taaagacgaa gttggtatgg ctgttattac
   175921 agaacttatg gatgtaagag atatggacga actgtatagt ataagtgata taattcaaat
   175981 tgggtcaaga aatatgcaaa actttactct tttaagtgaa gtgggaaaac aaaataaacc
   176041 tgttatgtta aaaagaggaa tagcatccac aattactgaa tggataggtg cttctgaata
   176101 tatagcaata gaaggaaata gtaatattat aatgtgtgag agaggtataa gaacgtataa
   176161 tgattatact agaaatacat tagatttagc tgcggtaccc attattcaaa aggaaacagg
   176221 tcttcctgtt gtggtagacc caagccatgc cactggagtt agatatttgg taaaacctat
   176281 gtcactggca tcttttgcat gtggagcaga tggaataatg gtagaagtac atcctgaccc
   176341 agaaaatgct ttgtcagatg gtgctcaatc tctttgcttt aatgaatttg aagatttaat
   176401 gaaatcaatt aataattatt aaaagaggca agagcctctt ttttattcgt aatcgttgct
   176461 aaggtaaatt tataagttat aacttgatag ttagattatt taatataaat aaagatttaa
   176521 tattgataga attaatataa aaaataaaaa ttttttgatt aataagaagg atatcaataa
   176581 aaaaagtcga attgtgtata ttgagtgatt gacaaattta gaatatagtg tagaatagaa
   176641 atgttaacac aaaaaattac accagaaggt gataatatga atgatataaa agacattatt
   176701 gaagaaataa aagctagatg cgatatagca agtataatat ctgaatatat gaatataaaa
   176761 caatctggag ctaattacaa aggattatgt ccatttcatg gcgaaaagac accttctttt
   176821 tatataaata catcaaaaca gatttataag tgttttggtt gtggtgaagg tggagacgta
   176881 ataaattttg tcatgaaaat ggaaaatttg gattttatgg atgctgtaaa aattttagca
   176941 aataaatgcg gtatagaaat taacactaac atgaatgaag aaactaggat taaaatagaa
   177001 aaatctaaga aatttcaaga tattcatacg gaagcagcta gattttatct ttcaaactta
   177061 ttgggaagca aaaatcttgg gtatgaatat ttaagaataa gaggactaga tgataaaatt
   177121 attaagaaat ttggtttagg attttctttg gattcatgga attcacttat gaatactcta
   177181 atcagtaaag gatataaaaa acaagactta ttggagtgtg gtctaattgc aaaaaataga
   177241 gatggaacta attgctatga taaatttaga aatagagtta tgtttcctat attcgattat
   177301 agaggaaata taataggatt tgggggaaga gtattagacg attctttgcc aaaatactta
   177361 aattctccag acacgttaat ttttaataaa aaacagaact tatacggatt aaattttgct
   177421 agaaaaaatt tagaaagtaa aactatagtc ttagttgaag gatatatgga tttaatttcg
   177481 ctttatcagt atggtataaa aaatgtagta gcaacccttg gaacagcctt gactgaacaa
   177541 caaggcattt taataaagag atatgcggac actgctatta tatcttatga ttctgatgaa
   177601 gcaggaataa aagcgacttt aagagctata gatatactta ctaaattagg tatcaatgta
   177661 aaagtgttag acttaaaaga tgctaaagac ccagatgaat ttgtaagaaa atacggactt
   177721 agtgattata aaaaagctat ggatgtttct actcactaca taaaatataa aatagatcat
   177781 cttaaaaaag aatttaacat tcaaaaagat gaagaacgag tgaagttcgc aaaagaagct
   177841 tctaaaatta taaaacaatt gacaagtcct gttgaaattg atttttatac aaagtattta
   177901 agcaatcaaa tagatattaa tgtcgagtct ataaagagag aagtttatgg taaaaattac
   177961 aataagccat ataataacaa aaatcaaaag aaaatagaag aaaaagtaat tgaaaaagtc
   178021 gaagtcagac aagacggaaa acaattagtt gaagaaactc taataaaaat aatgttagaa
   178081 gacaaaaaaa ttagagaaat agcgttactt aaagtagaag aaagtgattt tttattgaaa
   178141 gaaagtaaag aaattttaaa ttacatgatt aaaaatcaag aattggacaa aataactatt
   178201 gacaaattga aaagtttaaa catatccgaa gaatacttaa aagaattaaa ttcaatttct
   178261 ttgaatagta taaacttaga gaacacaaaa gaaatagaag gaataataac aaatatcaga
   178321 aaaaactcat tagaagagca aattaatagc ttgttgagag aacaacaaga attagaaaat
   178381 aataatgata tgaaagaggt agatggtaga gttatggaaa ttgctttaaa aatagttgag
   178441 ataaataaaa ttttaaagag cttgtagaga aaggaggttt gagtgtggaa aataaatcga
   178501 ataaaaaaga gttaaaaaag gttactgcta agacattaat agaaaaagga aaaaagcaag
   178561 gttctctgac acttgcagag ataatggaag ctttttcgga gactgaactt gataaggatc
   178621 aagtagaaaa tctttatgag actttaggaa atttgggaat agaaataaca gaaacaaaaa
   178681 actataaagc tgatatagat ttttcggttg ctgatgacga tttaagtata ggccacttag
   178741 atgaagatgc agaggcaatt tcacatgatg actcttctgc aatagaaata gaaactgtgg
   178801 atttatcttt accaaaaggg ataagtatag atgaccctgt aagaatgtac ttaaaagaaa
   178861 taggaaaaat tcctctactt aaaccacatg aagaagtaga atttgctaga aggatgcacg
   178921 aaggtgatga gatagcaaaa caaaggttag ttgaagcaaa cttaagacta gttgtaagta
   178981 tagcaaaaag atatgtagga agaggtatgc ttttcttgga tttaatacaa gagggaaatt
   179041 taggtcttat aaaagcagtc gaaaaatttg actatacaaa aggatataag tttagtactt
   179101 atgcaacatg gtggataaga caagctataa cacgtgctat tgcagaccaa gctagaacta
   179161 taagaatacc agttcatatg gtagagacta taaataagct aataagagta tcaagacaac
   179221 tacttcaaga acttggaaga gatccaaaac cagaagaaat tgcaaaagaa atggaaatga
   179281 cagaagataa agtaagagaa ataatgaaaa tagctcaaga ccctgtgtct ttagaaacac
   179341 caataggaga agaagaagat agccatttag gtgactttat tccagatgat gatgctccag
   179401 ccccagcaga ggcagcagca tattctttat taaaagaaca aatagaagat gtacttggtt
   179461 cattaaatga tagagaacaa aaagtattaa agcttagatt tggtcttgag gatggtagag
   179521 ccagaactct tgaggaagtt ggaaaagagt ttgatgtaac tagagagaga ataagacaga
   179581 tagaagcaaa agcactaaga aaactaagac atccaagtag atcaaaaaaa cttagagatt
   179641 atttagacta aaaagataca tcattgatgt ttttgtgata aatgccatga gataagtgat
   179701 atctcatggc tattttgtag taaagattta attttatttt tgtagttatt tcagtctaat
   179761 atctataact tggattaaat cctataaata aagggaattg aaaggagaat tatatttgaa
   179821 attaacagat agattattga aaatagcatc attagtgtca gatggtaaaa aaatagctga
   179881 tatagggacg gaccacggat acataccagt atatttgtta aaagagggaa aagtaccatt
   179941 tgcagtgcta gcggatgtta ataaaggacc tcttgacaat gcacataaag aagtcataca
   180001 gaacaatctt ttagataaag ttgatttacg attgggttct ggtatagaga tacttgaaat
   180061 aggggaagta gaagaagtga taattgctgg tatgggtgga atcttgataa gtgagcttct
   180121 cgaggctaaa aaagaagtag cacataatgt agaaaaatta atattacagc caatgcaagc
   180181 acaagaagaa cttagatatt accttttaaa caacggatat gaaattttag aagaagtttt
   180241 agtgagagaa gattttagaa tatatgagat aattgttgcc aaatatacag gtaaaaatac
   180301 tataatagaa gatgagatat attatgaggt tggaataaag cttttagaaa acaaagattc
   180361 tctttttaat gattttatag aaaaaaagat aaagacatat agttctatag ttaataaatt
   180421 agaagggaaa aatggggaag ctatagataa gaagagaaag gaaagcgaag ttgcaataaa
   180481 aaaacttgaa aatttaataa aataaatagg aggtatatat gctattaaag agtctaacta
   180541 gaaaaattga aaaaaagtat cctctaaact tagcagagga ttgggataat gtaggtctta
   180601 tagttggaga ttttgatatg gatgtaaaaa aggtattggt atctttagaa gctaatgaag
   180661 atgttattga tgaagctata tccaaaaata tagatttaat tgtgacacat catcctttta
   180721 tatttgggaa aattaataaa attaatagtg gagatttaaa aggcagactt atccaaaaac
   180781 ttattaaaaa tgatatatca ctttattcta tgcatacgaa ttttgatata gcatttgatg
   180841 gtctaaatga ctattttatg gaaattatgg aatttggtaa ttcaaaggtt ttagatataa
   180901 ctaaaagcga aaatttgtat aaattagcag tatacgttcc acataactat tcagatgaac
   180961 ttagaaaggt tttaagtaat tcaggagcag gtcatatagg gaattatagt gattgtacgt
   181021 tttcaataga aggtgaagga caatttaagc cattagaagg ctctaatccg tttcttggaa
   181081 gtgtaaatga tatagaaact gtaaatgaag ttaaaattga aactgtagta ccacagaagc
   181141 ttttaggtgg ggtaataagt tctatgttag atgcacatcc ttatgaagaa gttgcatatg
   181201 atttgtacaa gttagaaaat aaaggtgaga tatttggact aggtagaata agtaaacttg
   181261 ataaaagtat gacattagaa agtctttcaa ggaagataaa agagaaatta aacatgaaac
   181321 acataagagt agttggaaac cttagtacag acataacaaa agtagctgtt gtaacaggag
   181381 ctggttcaga atttgtaaaa aaagctaaga ggcaaggtgc agaagtacta attacgggtg
   181441 atgtaaagta tcatgaggca caagatgcac ttgatattgg aatgtgtata gtggattgtg
   181501 gtcattttga tacagaagat atattcaaaa atgttatgaa gagattttta gatgaattta
   181561 gtgaaattga agtaataaaa agtaatgtat atttgaatcc atttagtact atttagcagt
   181621 gtttgataat aaaaatacta tataaaaaat aaatttgagt ttaattaggg ggataatgat
   181681 gaaagtagca gtaatttttc atagtgtttg tgggagtaca tatttattag ctagagaata
   181741 taaagaagcg cttgaagaaa tgaatatcga ggtagatata tttagagtaa gtgacgaagt
   181801 tgcaaaaaca cttcctcaat attatttgat aaattccaaa gaatacaaag acgaatttga
   181861 aagtataaat gtaattaaat ctggaaaaga aatattagat tatgatgcta tatttatggg
   181921 ttcaccaaca tattatggaa atgtatctgg accaatgaag atgtttatgg atagtttttc
   181981 tgatatttgg gtaggtgctc ctttgagtgg taaaatattt ggttgttttg ctacagcagg
   182041 ttcacaacat ggaggaggag aattagcttt gcaagctatg aatatatttg cccaacatat
   182101 gggaatgact cttttgtcag ttccatgttc agtaagagga ggttatccag cgtatggaat
   182161 acttcatata gcaggagata attctgatat aagaccaaat gatgatgcca agataggtat
   182221 aagagattac ctaaaaagac ttaacatata agaatatcat ataaaaatac ctaaaagcga
   182281 ctgtatatac ttttaggtat ttttacttaa ttataaacgt gaagctttac cagaaatatg
   182341 gtcaatttct attttaacaa cagttgttaa gttcatatcc ttctctatgt acttcatgcc
   182401 ttcttcaaag aatcctttag aatatttttt tattatttct acaagagcat ttttcttttc
   182461 ttcattttct acagtgcaag cttttccaaa aactatagca ctagaataag tagtactaaa
   182521 tttatctgga ataacacttt cattagcaac tactaaaaaa gaaactttgt tgtttttcga
   182581 tatattatct aacttatgcc catttcttgc acaatgaaag taaatagaat cattaaagta
   182641 tacataattt acagcaactc cataaggata accattttca gatatagtgg aaaaagtacc
   182701 aaattcacca ttttttaata cttcaacagt atcttctttt gtcatttctc tttttttcaa
   182761 tctcatttct ttaaacataa tatcatcctt tctaattttg atgcttaaat taaattttag
   182821 aacatttata aagattatgc tatgtttttt acaaatttta agaaaaaaat atagtttaag
   182881 ataaaaggta gtgaaagaga agctatttgg aggtttattt atgatattat tgttagagta
   182941 gtacaaacaa tactaataaa tttaatagct ggtttcttgt tatttaaggt agtaagcatg
   183001 tctataagaa ggggaagtta tcgagggtag aagttgttat ttataacgat attataaaga
   183061 aaatattatt atataaaata ataaatagta aagaggtatc aagttgaata taatacttaa
   183121 tacctcttca aaattaagtt ataaaagtgt tgtgggaatt gtcctataca tggtaaggag
   183181 ataataaaga atgtatcttt aaagtctcaa ctaaacaaca aaatttatcc aacaaacata
   183241 caataaatgc ttctttgtat ctaggtggct taacagtaag tggccacatg tgttttaaaa
   183301 ttatgtccgt ttctttttca tttatttgaa aaaataaagt tgcatttttt aatgcttctc
   183361 tagggtgagt aaatccatgt aatccttttc tattaccttt gtaatgccaa tcataaagaa
   183421 aaaagtcgtg tagtaaagct cctctaataa cactttgaat atcaacactt aagtgcaatt
   183481 ttttacataa tagataacta taatatgcta ctgacaaact atgttcaaga catgaaacat
   183541 tgccatgatg aggaaatgtt ctcataagtt gaactttttc agaagaaagt atctcagaag
   183601 cacattcatt aaaatatttg atttcagctt ttgacaacat tatgaaaatc tccattctta
   183661 gtaatatata aatactatac ttcaacgata atatgaaata tttcttatcc tacaaaatat
   183721 aatacccaat aatacaagta agataccttt tatggtattt taaagtaaga gagattttat
   183781 taggctaaac aatgaaaaaa ttaaaagtaa agctatagca atatatagta tttttccaag
   183841 aggattgcca aaatttatag tccatccaat accaaacctt ttattaacca ttaatgatgg
   183901 gtcatttgga ttattataca tgatgcctgc tatccaatac ttctcatctt cttctggaga
   183961 ataagatgag ttgaatttta aatttgggga attaatatat gttgctatta aataaattat
   184021 aactaaaagc gttgtaatat tcatagcagt tgatagtttt gtttttattg ataaaagagt
   184081 agtaaaaaac tgtgttgtca ttataatcat caatattaaa aacaaataac caattttatt
   184141 taaatattta atgttttcaa ctctactttc ttcaattcta tttgtatcta tcttaatcct
   184201 tgactttatg gatccaatgg aagttatata taataaaacc attaaacaaa agtcagtacc
   184261 gattaattta aatacattaa gaaatgattt atctataaaa acatcaggag acccatttat
   184321 gttccaatga gtggcaattg agtctggcaa ttgattataa ttaaatgcta taaaaatact
   184381 cattcccaaa gtaaatagta tcggtattaa atagattatt ttaaattttt ttattatttt
   184441 atttttctta tttataaaat ccatatctac tattaatttt gaatctatat ctatatgacc
   184501 taatttagaa taaatttctg atttaagctt cttagctttt ttatgtgtat gaatatatag
   184561 tatactttca tataataaaa aacctataat accaataaaa taggaaagtt ccaatttatt
   184621 aaatgtaaag accagaataa aaactaatat aaagtctata ataaaaccta aagataatag
   184681 ttttttaaat tctttatcta actttataaa gtaattataa tttttatgct cttggtctat
   184741 agaaactcca tagatgtgtt ttttacctac aaaatagggc ataaaataaa atgtagcata
   184801 catcaaaatt agaactggaa atattgtaaa tagacattca atcttactca taatatttca
   184861 cctcatactt gtcaaataaa cttgaactta gtgacaaaaa ttcttcttta ctaatacctg
   184921 ataaataaga ttttgccacc aataattcca agtcaagttt atttttttga cgagttgtat
   184981 tatctatttt cattggtagt tgagctacaa tagcaccttt tcttctatca atatttaaga
   185041 atccctcttc ttttaattca ttgtaggatt tgttcactgt atgtaaattt acaccaatat
   185101 tttcagccat acttcttaca gatggaagtg attcatttat tttcaattct cctgaagcta
   185161 tagccttagt tatttcttct ttaatttgta cataaataga tttatcacta ttaaaatcta
   185221 aatttaaaac cataaaaaac ctccattatg ctttataaat gaaaacgatt gttatataca
   185281 tagtataaca taaaaaataa taacaaacac aaaatataag tttatatttt gtaaaaattg
   185341 taatttaaaa aataacataa tttttattaa aataatacag atactattta tagatagaaa
   185401 taaaaattag aaaggagaaa aaatatgtta acatatttaa tgaaaagaca aatgcataaa
   185461 aaagatgatg gaatgagtaa accaatgatg attacaggag ctgtaattac aggtgtagga
   185521 gcatatgctg tatataaaat ggtaaaaagc cataaatcta attctcaaat ggtcaataca
   185581 aattattatg gaaatagcga ttatgatgat tataaatatg acgaatttga ttatgactgt
   185641 gattgtagag acacaaaaca agattatgaa tatgaagaat taaaaaaaaa agtaaaagaa
   185701 tttaattcaa gaagaataaa ttgtgaaaat tgtccacatg tttctcaaga agaaatgatg
   185761 caatatgtaa atagtgttaa agatgtaaag gaagagattg atttacatga agatgctaaa
   185821 aaagataata tttacaaaga agatgaatac aaaaaatatg aagaagaata agtaatattt
   185881 tgtataactg aacaaatagt aatgtcaaat tatttaatat ctagttttaa tatgtaagtt
   185941 gtaacttaac ttgaaagaat cagtatcatt ctttagatag ttaagtaaca acttacattt
   186001 tatttttata aattttaata gttctttgtg actattttgt aattttagaa atattttagt
   186061 atccagggta attgtgtata ataaaacttg tatagatagt atgaaattaa gcagatagtt
   186121 taaaattaaa atgaaaagaa aggaaatagt tatgttaaag ttgttgatag ttgaagatga
   186181 tagtactata tcttttggaa taaagtatgc tttagaacaa gaaggattta gtatagatat
   186241 atcaaaggat ttatctagtg gaaaagaaat gatttcttct aatgaatata gcatgatact
   186301 gttggatgtt acattgccag atggaactgg ttatgagctt tgtcaatata taagaggatt
   186361 ctctcaggtt cctataatat tcttgactgc ttgtgatgaa gaagtaaata ttgtaatggg
   186421 tctcgatata ggtggagatg attatataac aaaacctttt agaattagag aattaatatc
   186481 cagaataaaa gctgttttaa gaagaaaagg taatacttca gaagaaaata agaaaatact
   186541 taaatttgga gatttaagta tatatacatt agaagctaga gtatataaaa atgataaaga
   186601 aatatttctg acatcagttg aatataaact tcttttaatt cttatacaga ataaaaatac
   186661 tgttttaagt agaactcaaa tattggaaaa actttgggat gtaacttatg attttgtaaa
   186721 cgacaatact ctcactgttt atataaaaag gcttagagaa aaaataggtg atgatttatg
   186781 tgaaccaatc tacatagaaa ctgtaagggg gattggttat aaatggatag gaagtgaaaa
   186841 tagtgtttct atataatcca gaagtgaaga agtttttaag taagtatgtt actttgatgt
   186901 ttattgttat cataatatct attggattta gcataatcaa cgtgtcttta actaaagaga
   186961 tggttgtaag aaataatcaa gctataatag ggactttatc aagtaagtat ccaaacttag
   187021 aaagtgatat agtagatata ataactcaag ggaagtctat ggagaacata gattatggtc
   187081 agaaaatatt aattaagtat aattatgata aatctattag gataaactct gagcctatta
   187141 tttctaaatt agttttagag actatcaaaa taaatataat attagtatgt ataatattta
   187201 ttttgatatt tgtgttggtt gttagatatt ttaagtcaat ttacaatgat ttatcagata
   187261 tgactaagta tgtttactat agttcagagg gtaagcaatt tgatatgaaa aacaagaatc
   187321 aagaagggca gataggtctt ctaaaaactg aactcttaaa gatgacgaca attcttaatg
   187381 aaaaggttga acttttaaaa agagaaaaga tatttttaaa caatacaatt tccgatatat
   187441 cacatcaatt aaaaactcct atgacttctt taataatgtt gaatgattta ttatataatg
   187501 atgtaccata cgaagtaaaa atcgattttt taaataagat aaaaaatcaa ttaaatagaa
   187561 tggattggtt gattaaaagc atgcttaaat tatcaaaggt agaagcaaaa gtgataaatt
   187621 ttaaaaaaga taaggtaaaa tttagtgaac tcatacatag agcaatgcta tctatgaaaa
   187681 tacctatgga gattaaaaat caaaaactga ctatagaggg aaatgataat gtatcttata
   187741 ttggtgatat tgattggtcc gtggaagcat tagtgaatat aatcaaaaat tgtgtagaac
   187801 atactcctga atttggaaat ataattataa cctataaaga aaatccatta ttttctgaac
   187861 taataataaa agatgagggt gaaggtatag ataaaaaaga tataccacat gtatttaaac
   187921 gattctatag aggaagaagt agctcaaaag aagatagtgt aggaataggt cttgcaatgt
   187981 caaaatctat aatagaaagc caaaatggcg atatatatgt aaacagcgaa aaaggtaagg
   188041 gtacagaatt tcatataata tttcataaaa tgtatgatag tgactaatct gtaatattta
   188101 attcacttta tagtaatagc caaaacctaa tatatgaagt atagaatata aatattggag
   188161 gtagttatgg aaattttaag agtagaaaat ctaactaaaa gttatggtaa aaatgaaaca
   188221 aaagttgatg ctataaaaaa tgtaagttta tcagttgaaa aaggaacgtt tatagcaata
   188281 acaggtccaa gtggaagtgg taaaagtacc ttattacatt tattaggagg agttgacaga
   188341 ccaactagtg gtaaggttta tataaatgat gttgatatat ataatttaaa aactaaggat
   188401 ttggcgatat ttagaagaag aaatataggt cttatatatc aattttacaa cttaattcca
   188461 gtcttaaatg tgaaggaaaa catattgctt ccagcagagc ttgacaatag agatattgat
   188521 agagaatatt ttgaggattt aatgaaaaca ttaggtctaa ttgatagaga aaagcacctt
   188581 ccaaaccaat tatcaggagg tcaacaacag agaacctcta taggacgtgc attaattaat
   188641 agaccttcta taatattagc agatgagcca acaggtaatt tagatagtaa aaattcaaag
   188701 gaaatattag aattgttaaa attgtcagta aaaaagtaca atcagacact aataatgata
   188761 actcatgaca aaaatatggc acttcaagct gatagaatta taagcataga agatggaatc
   188821 ataaaaagtg atgaggtgat gtagatgaat ttatatacat cactaaccat tagatactta
   188881 aaacaaaata aaagaagaac cattgtaacc ataatcggta taatactttc aacagcttta
   188941 atttgtggta taggaaatat atttgaaagt tttatggatt atcaaatgag agaaactata
   189001 aagaatgatg gaagtttcca tgttacattt tatgatgtaa atagaaaaaa tgcggaatat
   189061 gtaacgaaat cagctgaaat agaaaaacat gcatttacca aacaacttgg atattctaaa
   189121 ttagaaaata gtgaaaatgc tatattaagt ataaagcaat atgataaaaa tgcaataaac
   189181 ggatataaag tttctataaa agaaggtaga tttccagcta aggaaggaga aattgtttta
   189241 agtgaaagta ttattaatct tatagatgat aagtttaaaa taggagataa gataacttta
   189301 aaagtagggg atatgtttga ctcaagcaag aaaaagattg atagtatgac atttcatgaa
   189361 ggtgattata tagcaaatga aaaagataga acttttaaag ttgttggtat aattgaaaaa
   189421 cctgggtttg aacgttataa tggaattgca acagctatag cctactttaa tcctatgaat
   189481 aattacaatg atacaattaa tgtatcagta gcagtaagaa atcctaaaga tgtgtataag
   189541 ataagtaata aaataagtaa aaatatatat tcaaataaag ataaagaagc agtttctgat
   189601 atgataaaat acaatgaaca tttattgagg ttacaaggtg ctagtaagta ttcaaatata
   189661 aatagctcta taaagtctat aattatagca gtaactattt tagtaatcat atgtacaatt
   189721 gctacagtgt acaattcctt tagtatttct ataaatgaac gaaaaaaaca gtttgggata
   189781 ttaaattcta taggtgctac atctagtcaa attaaaagat tagtttttat agaaggtatt
   189841 ataattagtt taattggtat accaatagga ctaatatctg gaacagtagc tatagactta
   189901 ttgtttaaaa ttataaataa gtattttact gaatcggttg ttactaagat gagtttgcag
   189961 atagtgtata atccaataat aattattgtt agtataataa tagttttgct tacaatcttt
   190021 atatcaattc tactacctgc aatatcggct tctaatattt ctccccttaa tgtgattaaa
   190081 aatactggag agtataaagt gggcaaaatc aaaagctcaa gacttattaa aatgattttt
   190141 aaaactgaag gagtacttgc atataaaaat attaggagaa atagaaaaaa atttataata
   190201 actctttttt ctttaatggt aagtataata atatttatat cttttagtgg ctttacatta
   190261 cttttactaa gaggtgaaga aattagaaat tctcaaagaa aatatgattt gtatttaact
   190321 gcaaagaaca cagctaggtc tgtagaggat actataagtg aactagaaga tattgatggg
   190381 ataaaaaact ttgaattggc aaccggacaa tatgtgtcta taagagtaag tgaaaataaa
   190441 ataaataaat ccaaggaaga tttaatcagg aaatattatc aaaaatataa gattggagat
   190501 agttatgaat atgatttcag taataatgaa ttaatttttc caggagattt tgcagtaaaa
   190561 aacaaaataa ataacttagt acagggttct tttaataaag agagagcaat tgaagaaaat
   190621 ggtgttatat tagttagaaa aagtgcattt gaagaaaatg ggaagaaagg tgtagtagaa
   190681 cttaccaact ataaagtagg agatacagta aattgtgaat atcttgatga aaatgcctta
   190741 agtaaaaaag taaaggtcaa gattcttgct ataactgatg aagaacgtct aggtcttggt
   190801 tatcaaaata tggggttaca atttataact tatgatgaag ttgctaaaaa tttaaattta
   190861 aaattaagta aaagtcttat atttattgat tcaggaggaa gcattaagac taagaaggaa
   190921 atagaagctt tggcaaataa aaataatttt aacttttatg atgaaagtgc aagcaatgaa
   190981 agtgaaaaac aagatttaaa ggttattaaa atatttgtat atggttttat agtagtgata
   191041 tctttagtga gtgttacaaa tattctaaat acagtaagta caagtataaa tctaagaaaa
   191101 agagaacttg cagtaataca atctataggg gttactccta aaggatttag gaaaatgata
   191161 tatttagaaa gttttatata tggtatactg tcattgttgt ttggaatacc aattagtatt
   191221 ggtataattc taattatgaa taaacttatt tcaggtgtaa ttgaattttc tccgattata
   191281 ccgtggacag ccatagttat ctgtatagta agtgttttta taataacttt tatagcaggg
   191341 tatataccaa tgagtaaatt aaataaagaa aatataatag ataatataag aagagaaagt
   191401 atatagatat aaaaataatt cttaactata taaaatatta ttaaaatcat ttaagtggta
   191461 taaaatatta ttatatcact taaatgattt tttatttata taagaaatct aataataaat
   191521 tactagaggt atttaactat ttagaaagaa ttggtattat ataaagtaag agaatatata
   191581 ataagaaaga atatttgatt ttattggaaa acaaaagaaa aagaaggtga ttactatttc
   191641 tcatataact gcgaagaata tgtataaaag tttagaggaa agaataaaca agtttccaca
   191701 aggtgctcca ccatctgata cattatacaa aatactaaat gtactatata cagaacaaga
   191761 ggcgaagtta gttgctcagc ttccaataaa gcctttcaga gtaaaaacag cagctaaaat
   191821 ttggagtgta agtgaaagtg aagcatatag agtattggat aaacttgcta gtaaggctct
   191881 gatactagat atagaagata ataaagggaa gaaatatata atgcctcctc caatggctgg
   191941 tttttttgag tttgccatga tgagaacgag acacgatata gaccaaaaac ttttggcaga
   192001 gctttactat caatatatga atgtagaaga agattttatc aaagatttat tttattcaac
   192061 agaaacgaag cttggaagag tatacgttca agaggaagtt ttaactaatg ataatgaggt
   192121 tagtatttta gactatgaaa gggctactca tataattgat gaatcaactc atataggtat
   192181 aagtatgtgt tactgtagac atagaatgca acatgttgga aaagcttgtg atgctcctat
   192241 ggatatatgt atgacgtttg acaatgtagc aaattcttta ataaataata aatttgcaag
   192301 acgtgtggat aaaatagaat gtaaagaact acttcatcaa gcatatgaac ataacttagt
   192361 tcaatgtgga gaaaatgtta ggaaaggggt tacgtttata tgtaattgct gtggatgttg
   192421 ctgtgaagca atggtagcag ctaaaagatt tggaaatctt catccagtac agacaacaag
   192481 ttttatacca aatataaacc atgaaaattg tgtaaagtgt ggtaaatgta taactgcatg
   192541 tccaatagat gcgataagca aggttaagga agatggtaaa gaatatataa aaattgatga
   192601 ggatagatgt ttaggttgtg gagtttgtgt tagaaattgc cataaaaata gcattatgtt
   192661 attaaagaga gatgaaaaaa taataactcc agcaaattca gtacatagag cagttcttat
   192721 ggcaattgaa aaagggcagt tacaaaattt aatttttgat aataatgctc tggctagtca
   192781 tagagctatg ggagctatac tgtcagctat attaaagctt gaaccagcta aaaagatttt
   192841 agccagtaaa caattaaagt cagtatattt agataaattg ttaagtatga atgataaata
   192901 gaaactaact taaaaaaggc aaagttttag acttatctat atcttaataa acctatcatt
   192961 taatatttaa atttaatttt tacacatata aaacttataa cttaaataaa aaaaggctat
   193021 attcaattaa tattacttga atacagcctt ttttagttat gttaagctat ttcttttatt
   193081 tgcttaaatg agttttcatt tccatttcca ccaatttgtg ttacagattt aaatctcata
   193141 gttttaaata gttctttttg attataatct agtgagtttc ctactagcat tacaggagat
   193201 ttagtttttc cagccaaaac tccaacagat aatccgtcta ttaaatcatc ttgtttattc
   193261 attccatttt tagcaacata taaattgtct atcttagaat ccttgtaaaa ttcttttatt
   193321 acttttgcat tagtttcatt tctagtgcta cctgatattc tctgtggatt ttgaagttta
   193381 ctttctatat ttttagaaac tgtatattct ccaccgatta cataagattt atcaatcttt
   193441 ttgtttttaa acaagttatt tatttcagtt atattactat tttcattagt aagtattata
   193501 ggcatatcat tttgagctga tacagctcca atgcttactg catcggctaa tcctttttcg
   193561 ccattaacta ctgaaatctt tgatatattg ctaatattgt tcaattcttt agcaatgttc
   193621 atagaagttt gatatctatc acttcctgaa attctagata cagagatatt gtttgatttt
   193681 atagtatcta aagatttttc atttatagaa gcttctccac caactacata tacattttta
   193741 acttttaatc tctttaattc agccaaagtt ttttcattta tttgagagct tccagtcaat
   193801 aatataggag cgtttttctt gtatgcaaat ggtgttgcag ccaaagcatc tgcaattgct
   193861 gaatcgttta ttaaaactgc attttcagca ttttcccaac ctgcttgact tatcttaata
   193921 gaagtttcat atctatcagt tcctgtaagt gcacttgcat ttacttcatc ttgatatgta
   193981 acctcaaatc tagcatttgg acttcctaag aaaacaatta cgcctccttt tggcaatcta
   194041 actctattgt tctttgtaac taaagaatag tttacaggaa cacctttatc atcataaaca
   194101 gcaaaagatg aattttgagg aagattaact tctatttttt tatttgcgat atcgtcacca
   194161 atcttatacc attttgcata accattggat tctagttcac aagtaaaaga tttttctgct
   194221 ggcaaattag ttatagaatc ttcactaaca tacgttagtg ttccaaaaga taaatactct
   194281 gtaccatttt ctttatgaag tttaatgtcg gataaatcac gacctattac accaggtatt
   194341 tctataaaag catttgagtt attctcatcc attattttag tgttaactat ataacctgga
   194401 gtttcatcag aaagagcaag agttgccttc acagaaccaa acatatagct ttgagaagta
   194461 tatttttcat ctactagata gtaatcttta ccatttcttt ttttccatgc ttcttttaca
   194521 ctatttgata tattgttgtc atctatcttt tgagctacat agtataaact tgctgtctga
   194581 cctaatccag ggacatcatc ataagagctc atatttaaat atgtgatatt gtttttttct
   194641 tttacaaatt ttagacagct gttacctttt tcagatacaa atctatcttg acctatgtat
   194701 acgtatttat cttcaggtcc attttctata taaggagaag atactgttaa agtaccatta
   194761 tcattaacat ctacttttat catatttgaa gaagcataaa gaccactatt ttcttttaga
   194821 gagctaggca ttttaacttg ttgtggttta ctaaatgttt tatcaggttt tatttcttta
   194881 attttacctt tttcttttaa tgcagatagt aagatttctt gtccaattat ttcgttaagt
   194941 tgactacttc caccagaaga aagaactgca actgccatat tttcatctgg aagaactata
   195001 agattactgt ggaataataa agagtctcca ccttttgtaa gagcttttaa attatactga
   195061 ttaaatggat aagtgttgac acaatcccaa cctaaaccat atccaagtat agaatcttct
   195121 ccttcaggcc atagaccatt taaatattct ttgttttcca tagcttttac tgaagcagga
   195181 gaaagaatac catttgaatt tttcataaat gtttgtgcaa atgtacatag attttctgca
   195241 cttgaatata aaccacctgc acctatagca ttaaggttat cttgcggaac tgcatcttcc
   195301 caataaggta catatgcttt tgctagtttt gaactatcaa aactattttc tggagttttt
   195361 gtattttgta agttaagtgg attatttatg tatttatcaa gaaaattagt aaatgacata
   195421 ccagatactc tttctactaa aatttcagct aaagtaaatc catcattaca ataaacagaa
   195481 aaagctcctg gtttagcttt taatctttgt ttttgtaatt cttttaagaa attatcatga
   195541 ccataagaat cattgtctgc taataaaata gtgtttttaa aactacttcc catcaaccct
   195601 gatgaatgat ttaataacat tcttggagtg atttccttgt atctatcatc agccatttta
   195661 aattcaggta tatactttac aacaggagta tctaaattta attttccatc atcaaccaac
   195721 ttcataacag ctgttgtagt aaacatttta ctgatagatg cgatactata catattatcc
   195781 ttatttaagt ttttgttatc ctgtttgctg taaactccac cattaccaga aatctcaatt
   195841 ttgccattat caatcaaagc atattgagca cttacagcac catactttga tagcaaagtt
   195901 tggattttct ctttagcaag agctttagtt tttgtgtaag attccgcgtt tttactataa
   195961 tcatgtaatt ctatatcaga actttgatat ttttcggaat tatcttttgt attatcagca
   196021 aaagtaatat ttggagcagc agtaaataac atactcaata ctaatgtact agataataat
   196081 ttagagagcc tttgcttaaa catattacat tacctctttc cctttttaat aatttataat
   196141 tagcataaca ttcttaatta ttttaatcaa cagattatta tcaataaaaa aagcttttat
   196201 aagtatagct ttttatataa cagagaaaaa tataaaaata atatttgttg ttgtataaag
   196261 aataaagggt ataggtaata tataaataaa atggaggaat tttagacata tgtacaagaa
   196321 tataaataag aagcaactta aagaaatgat gaaaaatgaa aaggatattt tattattgga
   196381 tgtaagaact aaagatgaat ttaaggaata taaaatagaa aatgctataa atatatcttt
   196441 acaagagtta atcaataata tagatgaaat ttacgattat aaagataaga aagtagtagt
   196501 ttattgcaga agtggtcata gaagtgttac tgcatgtaat ttgttagctg aagaaggttt
   196561 tgagcattta tataatttaa attcaggaat aattgattat atgagttaaa taatgtaagt
   196621 tatacattaa atactatgta tagctctgct tattaagtag gaatatatct aaatatttat
   196681 aagataaatt taggaaagaa cgaatttttt cgtttttttc tatgacagtt tttgtagtaa
   196741 atattagttt ttaagttgga aaaaggtagt agctttttag ctactacctt ttaatatgaa
   196801 cttagaatat tattaaaaaa atatatttaa agacagaatt aattttttaa tgaccagtta
   196861 aattactatc gccaaattta tcattaaatg gttttataac tctatttata ggtcctttta
   196921 gaagtacatt taaacaaata gacagaatca taaatagtaa tagaactagt atatctttag
   196981 ttagatttgg agcatatata ccaccaactg cttcccttgt agcacctatt gcataggtaa
   197041 atggcattat agggtttatt ctttggaaga atgtaggtgt aacttgtata gggaatgtac
   197101 caccagaaga accaatctga acgactaata gtactattgc aattgctttt cctacatttc
   197161 caaatacaga aactaaagaa tacactataa agttaaatac catactagta aacataagca
   197221 gaactatcaa taaaattgga tgttttgctg ttactcctaa caataatata tctccagttc
   197281 ctattataaa accttggaca agagctatac ttaaaaaagt aaggcctctt ccaaagtaaa
   197341 tttcataagg tttatagttt ccatgtacag atgtagataa tagtgctgaa ataagtaata
   197401 taccaaccca tgtagaaaga acactataaa atggtgtcat tgcagaacca taattttcaa
   197461 ttggatataa tttctctgtt ttcacctcaa caggttcttt taagaaatta gactttgtca
   197521 atatatcact ttcaagcaag ctgactaatt ttttcatatc ttcaccatta ctaattttgc
   197581 ttaaagtatc aatcaaatca tccaacattc cttttgctaa aggaagtctt tctcttatca
   197641 atgatatact ttcctgtgca tttcctgaaa gttttagaga agtagtaagt atttcttcaa
   197701 cctttggaag ttttgcttct gccttatcta aaacagtaat tatatcattt gctactttta
   197761 tactgtttgc aaatatacta tttataggtt ttgatatttt tgagtcaaaa ttatttaaaa
   197821 tatttaaatt aattcttcca ataccatttg atagacttaa aacattattc aaagcactta
   197881 tagatggttg ttgtccagat ataactttgt ttttaatatc atttaatgtt gatatagagg
   197941 aatctatttt attgctagag tcttcaagat tatctattac atcatccaat ctattatttg
   198001 atgtaagttg gtttaattta gttaaaaagt ccaccaaagt atcgtttaaa gattgcaaat
   198061 tagaaagttt ttctgataaa ttatctatca acttaggtac atcttcactg ccactattta
   198121 ctgcatcaat taaatttaat gtaagagaag aagcagaaga tgaaaggtca accattaaat
   198181 ttaagtcaga cttaataaga ggagaaagtt cgtctaaatt atcatttgta tcctctaaga
   198241 atttttttaa gtcacttgat aatagttttg tatcattcag agtcttttta attgtaggta
   198301 aatcagattt aatatcttta actgtatcag ataattttga agtagcatca gaagctaaat
   198361 caacagtctt atttatatgg tcaaatctct tttgaaggtc aataagggaa ttttcaactt
   198421 ttgtcaattt tggaagactg tgttcaattc ctgcaccaac tccgtttgat ataccaagaa
   198481 cgatttcact aactgttttt actatagtct gattaacctg tagttgtatt gtagaagcac
   198541 ctttatctgt aatctttggt gcaactgcat ttattttttc attaacagta tagataattt
   198601 cgcctttttt aacatcatct gtaattaaag atgtcaaatc ttttgtaaaa ttttttggaa
   198661 tcttaagtga tgcataataa gtaccttttt taacaccttc aagagcagtt ttttcatcta
   198721 caaactgcca acctaaactc ttgttatctt tgagttgttc aattaattgg tctcctacat
   198781 taatcttttg tcctgctatt tcatttcctt tatcttcatt tgttactgct acaagcatat
   198841 tagcagtgct tccataaggg tcccaagatg cctttatatt gaaccaagca tacagagatg
   198901 gtaaaaaagc aagacctaaa actattacaa gtacggcata attgccacgt atatctttta
   198961 ggtcactttt aaaaatttct aatatatttt ttaaaccctt tgaaggtctt aaattcttga
   199021 tattattcca gtttaaaatt tcttttaaac tattagtttt tttcaaatgt ctcacctcct
   199081 aaaatatttt gataaagaaa aaagttagat ttataatcaa ttttaaatta tattactttt
   199141 tacacaaata gtaaagttaa aattttgtct taattttaa
//
LOCUS       DAEORM030000002       167902 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.002, whole genome shotgun sequence.
ACCESSION   DAEORM030000002 DAEORM030000000
VERSION     DAEORM030000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 167902)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 167902)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 167902)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..167902
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.002"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            159..3746
                     /locus_tag="KRH23_000182"
     CDS             159..3746
                     /locus_tag="KRH23_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5223482.1"
                     /translation="MQQKCKKKALSMILSISMGFGSVASFNASNIFADTIEESTNAGS
                     TEGNANAGSAEGETNAGNAEEDTNAGNAEEDTNAGNAEGDTNAGNAEGDTNAGNAEGD
                     TNAGNAEGDTNAGNAEEDTNAGNAEGDTNAGNAEGDANAGNAEEDMNALVVEEATAED
                     PTSVGDFKISGGEINVDFKFASGVLTILSGKQMTIQNNNPNTPTTHRIVIPKDVKAEL
                     IFDGVNIKTASNSPFTLTPDKDGGAYAHVILQDGSENKLESGDKPYPGIRAGKSTTLI
                     IDDSIVNRDIEGEFIVPENGKIPRDVTLENGDKLKKGDRLTLLDSKNSGSLTAVGNSY
                     AAGIGGGDTENGGNIIINGGIINATAKEGSNTVYGAGIGGGRIGDGGDITINGGTITA
                     KGAYHGAGIGGGYYTGISINILNPSVVDPSSGYGYSGNITINGGLSYSYGGAHGSAFG
                     DGCTKIGVSRGYRVLVTGGTVLPYITGTETWLSDLSAVAGDVIVTGGSLKATTFKSNG
                     GVAVAYGDLEKKTEVFMNKISLTYLGQDKVNTTLVEDFKMLINGKIYPYGAPSYTDDQ
                     GVLYLWFSDQFKKSEVSVNLVVIDKITGENIKPNDFYIKDIGSGSQYLKQYEEFTIDN
                     TPPYLINKRYDGLPFEEDVEKGFLDWLLKDGGIPITTPAGEKLTDKKFMTISSQRLND
                     ETMEPDINLGSDEFTKQVDAGKYQLNITSTQFSNEYPFNEAYWGHRAFYKAEIIPADA
                     ETSLVVEESKVKTDVFKPTDTFTLNATVSPDKKEGPDCASPRGYVQFYINGKEYKNPV
                     ELKTHNKGSESHNYSTASIEWRPLDNNHHIFTTEQTITVKYIGDDINYIEGSEDEKKL
                     KLDMTNVDVDGDGKPDINIDTDGDGRPDINIDTSGDWKPDINIDTDNTGEWKPSTEGG
                     NGDGIWKPDKNIDTNGDGNPDTDYNRPAIDADNDGVDDYWKPDKNVDTGSGGYDTGNP
                     DPNKPDSGNGGNSKPDSGNGGNSKPDSGNGGNSKPDSGNGGNSKPDSGNGGNSKPDID
                     TDGDGKPDIDIDGDGKPDINIDTDGDGKPDINIDTDGDGKPDVNIDIDGDGKPDVNID
                     IDGDGKPDINIDTDGDGKPDINIDTDGDGKPDINIDIDGDGKPDVNIDIDGDGKPDIN
                     IDTDESLDSNVGQNVQTGDQSNIMLDLALMFISLFFLIKNLTNKYLRRK"
     gene            4508..5470
                     /locus_tag="KRH23_000183"
     CDS             4508..5470
                     /locus_tag="KRH23_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HHS5223483.1"
                     /translation="MAKIDNMMSILWMLNSDKKITAKQIAEKLEINIRTVYRYIDVLS
                     ASGVPIISDTGHNGGYSLLNNFTKAPLFFDIEEQKSLLHAALFAKKEGYFLDEALDKS
                     ILKLKMYSNQKQEDILTNHLIALEVIKPIGKVSIESVLKKLENSILKELSVEINYHAG
                     RKAKSKYRIINPYGIVHWNNNWYVVAFCNMRNEVRSFRVDRISEIIETSNTFNRPTEF
                     SASEFFIKGIIPEIKDEQNIIQLVVEGSIDSLDSLSQHWFLGHYLKERTPNKIIFMLE
                     EEVICKYIPNILLPYRKTIQVIEPLSLRKKIIEDLLELIDYYQI"
     gene            5549..6178
                     /locus_tag="KRH23_000184"
     CDS             5549..6178
                     /locus_tag="KRH23_000184"
                     /EC_number="3.2.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0019172 - glyoxalase III activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase family
                     protein"
                     /protein_id="HHS5223484.1"
                     /translation="MKNRKVYMYVFDTMSDWEVAYLTAELNTGRYFKKGLKPLKVITV
                     GIDKNPIITMGGLKVLPEITVDEFNMESKDLLILPGGNTWLSMNHEIILEKVKEALIQ
                     DSIVAAICGATLGLAKKGLLDFRNHTSNDLEFLKMVIPNYSGEKYYKTESVVSDENLV
                     TASGIAPLEFTFQVLKLLDVFESEALNSWINLYKTHDSKYFFELMNCNK"
     gene            7011..7424
                     /locus_tag="KRH23_000185"
     CDS             7011..7424
                     /locus_tag="KRH23_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5223485.1"
                     /translation="MSKSELGVKTNLVSELLMISYFFIDSLLKKFIFKDGNLCITFII
                     LFAFWACDFMYNKKYNDLVDEASKLMLLKVDHIASKIMLYSILLIAVFFSANYTRGLD
                     ISNLDIGIILLAILFIQSLSKLILYIHFDRKGICN"
     gene            7492..7908
                     /locus_tag="KRH23_000186"
     CDS             7492..7908
                     /locus_tag="KRH23_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5223486.1"
                     /translation="MSKSETGVRSKLILELLVITYFFIAVLATKYIFKGPSTASLPGL
                     SWLIVFGCYSIYNKKYNDLVDESSEFILSKVNKIAIKIMIYSIVIISIFFATPYTSNI
                     NISNLDTGIILIAVLFIQSLSKLVLYIYFDKRGICN"
     gene            7909..8121
                     /locus_tag="KRH23_000187"
     CDS             7909..8121
                     /locus_tag="KRH23_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HHS5223487.1"
                     /translation="MAILMKTKIKEYREKLLMTQNELAKLVGVRRETIVHLENGKYNP
                     SLKLAMDIAKVFDTTVENLFEFIEEE"
     gene            9165..9998
                     /locus_tag="KRH23_000188"
     CDS             9165..9998
                     /locus_tag="KRH23_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HHS5223488.1"
                     /translation="MVIKKVFNNNVVFARDNSGQEVILMGKGIGFNKFTKDLVEIDKI
                     EKKFIFNNEESLSELHSLLDRIPLKDVELVSEIIQMGREELGDNLNDSILITLSEHIS
                     YMLKRMDEGLVFQSPLQWEIRQIYPNEYNFSKKAVEYLRKKLDKNIPDSEIAFITIHF
                     ANAQLETKDMQETLLLTKIIDNVLDIIKYHYGIEINEYSFDYTRFISHLRCFIKRQLS
                     GENTNVDTSLLDIIKMKYKSDYNCAKKVKNFLEKTYKWKISENELLYLTLHLNRLSNI
                     K"
     gene            10124..11965
                     /locus_tag="KRH23_000189"
     CDS             10124..11965
                     /locus_tag="KRH23_000189"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HHS5223489.1"
                     /translation="MKFERESEEIIKYVGGKENIISLVHCATRLRFKLKDTSKTNKEE
                     LLKMKDVLSVVNSGGQYQVVIGNKVTDYFETIIKKAVLQGQNTEEQGEKVSIVSKIFE
                     SISGAFSPLIPALAGAGMIKALLTILTTMKWMSDTSSTYAILSAAGNAVFYFLPIFLG
                     ITLAIKLGANPYVGGVIGAALLDPNFTALIGAKGGANFFGMPVTAIDYSFGVFPIFVA
                     IFIYYYVDKLLKKIILKDLQLFLVPMISLLVMVPLTVILFGPIATNVGDIISNIFMGL
                     FEFNRVIAGAAIGIAMPFLAVLGLHWGFTPITLQNLATMGGDPIEGAAVAAVFAQIGI
                     AIGLFMKVRKSKKNSELKVLAGSTAVTGILAGVTEPIIYGIILRYRRMIPVLAIAGGI
                     GGGICGVFGVTCNAYVFHNIFSMPVYTPFLGYILGIGTALVLGAVLSYFFGLSKEECE
                     EGNEEVAFDEDDGIEEILSPIEGLQIELSEVEDEVFASGTIGNGMAIIPSKGEVVSPV
                     NGTITTIFPTKHAIGITSDKGVEILIHVGLNTTMLDGKYYTTHMNAGDKVKKGDRIVS
                     FDKDKIEGEGYSIVTPIILTNTNDLADVIVKENKHIKIGTPVIKVVY"
     gene            11988..13421
                     /locus_tag="KRH23_000190"
     CDS             11988..13421
                     /locus_tag="KRH23_000190"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HHS5223490.1"
                     /translation="MKSNQEFLWGGAVAAHQVEGGYNKGGKGISIADVMTAGTHTISR
                     KITDGVIEGLNYPNHEAINFYENYKEDIRLFAEMGYKCFRTSIAWTRIFPKGDESTPN
                     EDGLKFYDDLFDELLKYNIEPVITLSHFEMPYHLVKNYGGWRNRKLIDFFVNFCEVVM
                     NRYKDKVKYWMTFNEINNQSITTNPIYAFTNSGIIYEEQEDKEEVMYQAVHYEFVASA
                     KVVKIGHEINPEFKIGCMVAAMPSYPYSCNPEDMIKFVESNREQLMFTDVHVRGHYPK
                     HTLKLWERKNYNLDITEEDKKILKEGIVDFIGCSYYLTTVVTADKTMKTTGNDSAGKA
                     DVIENPYLKTSDWGWNIDPVGLRFYLNQLYDKYELPIFIVENGFGAEDVLKSNNTVDD
                     DYRIEYLASHIREMKNAIEIDGVDVIGYTVWGCIDPVSFTTGEMKKRYGFIYVDRNND
                     GSGTLKRHKKKSFDWYKNVIKFNGEIL"
     gene            14123..15001
                     /locus_tag="KRH23_000191"
     CDS             14123..15001
                     /locus_tag="KRH23_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HHS5223491.1"
                     /translation="MLINMKEMLKVAQENQFAVPAFNIGSGQILKAVVQSANEKNAPV
                     ILAIHPNELSFLGDSFVASCIEEANKSKVPMVIHLDHGENKEQILRAIRCGFTSVMID
                     GSHLPYEENVAISREIVEIAKGLNVSVEGELGTIGTTGTSSEGGTDEIIYTDSKLAKD
                     FVEKTGVETLAIAIGTAHGIYPKGFKPELKLDLLKEIREVVDIPLVLHGGSSNPDEEI
                     AQAVKLGVCKINISSDVKSAYYKKCRELLEQNPSLYEPDTIYPPCIKAAREVIEFKMN
                     LFNAIDKLKCFYKNKN"
     gene            15037..16932
                     /locus_tag="KRH23_000192"
     CDS             15037..16932
                     /locus_tag="KRH23_000192"
                     /EC_number="2.7.1.202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005351 - carbohydrate:proton symporter
                     activity [Evidence IEA];
                     GO_function: GO:0022877 -
                     protein-N(PI)-phosphohistidine-fructose phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_function: GO:0090563 - protein-phosphocysteine-sugar
                     phosphotransferase activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIABC"
                     /protein_id="HHS5223492.1"
                     /translation="MIGKILRSDCIVLDKQLQTKKDVINYMANHLYHGNYINNKEKFI
                     ADINKREKESSTNMGNLIAIPHAKSNVVNQPVMMYLRTDREITDNDGQKLRSFFMIAV
                     PESGSDEHLKIISKLATYLMEENFLKHLLSAETPYEILSIFNNKAAESGDFSNNQNKG
                     LIVGITGCPTGIAHTFMAKKALEEAGQELGYEVKIETHGAIGVENKLTKEDIKRAEYV
                     IIACDKEVQLSRFIGKKVLQKKVVDAKNVSLAKNLIINAENGMAKEIKPGGKTLEDSK
                     EMLQGSEKKGVYKHLMSGVSEMIPFVVIGGIGIAIAFMFGIFASDPTHETYNPIAGFF
                     GQLGGDSAFKLFIPILAGFIAKSIAGRQGFAPAMIAGFMAVIGGSGFIGGMVAGFATG
                     YIALGVMKITENLPDVLKGVNAVLICPLLIAFTSGAIMFFVVNTPASWLNEALQSWLQ
                     SMSGTNKVLLGAILAGMMASDMGGPINKTASAFGLAMFSSNIFEPSAALMVGGMVPPL
                     AISLAMLIFKNKFTKEERKSSLPTAIMGASFITEGAIPFAAADPLRMIPANIIGSCIG
                     GAICMSLDITLMAPHGGIFVIPFACSAPVAYIACILIGTVITALIIGVTKPTIRSENS
                     KVELLGA"
     gene            17200..19107
                     /locus_tag="KRH23_000193"
     CDS             17200..19107
                     /locus_tag="KRH23_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HHS5223493.1"
                     /translation="MLVSRQIEFLKLILNENKYRPIKYFKDKLNVSDKTLQKDLKMIE
                     KYLETFNIKIDIKRGYGILIEDLAKKNIDLINSLNIQSKENKSLSVEQRRMEILKYLL
                     LNSNNITSINQLADKYYVSKTSIVNDFKYIEAWIKEYNLKLNKTLEGTKIIGKEVDIR
                     KSIAKMMDDLLDENYEQHDISELTRLDSATFSALINLFDIDSIIFVETIITELEYNLG
                     YTINQPYYINLITHILICLKRIEEGNQIESQEEREISVDNLDELVYKNVSILIDKIEN
                     RYRVKITKDEIMYIYIFLVSSGFSSENNSSYNDESDRLSESEKVSSIMIENMSRFLNI
                     NLKNDDLLQKSLASHVRPMLNRLRYDIQIKNPLLGEIQERFSDVLGLCMMTINIMTEY
                     DNLKNISIDEVSYLATYFQAAIERNMSSKRVIVVCHTGYGTSQLLAARLKREFPEWTI
                     VDIVPMHQLSKRNLDDVDFVISTVNLDLKDKLHIVVSVLLMENDINNIKNALLSKPKK
                     SMNLDTNLLGMYLEDNIYFNFDVAQMESLIGVNLGSKYESISLGKDLNIYIHKQSKLN
                     KEIMNINNVTRTIDIYLEISNQSFLKNILMEISNLYRQKNYINYIIDCKSKEDIKILF
                     KNNLLEKTNGN"
     gene            19097..19546
                     /locus_tag="KRH23_000194"
     CDS             19097..19546
                     /locus_tag="KRH23_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HHS5223494.1"
                     /translation="MEIREILTEESIILDLKSTTKEGIIQELVDKLYDTGSITLKSKF
                     IKALKHREKIGSTSIGYQMAMPHGKTKYVKKASVVIGKSKKGVDWPSIDGLPVKVIIM
                     FAMPQSGGNEDMILISKIAYILGGKNIGERLLNAHTKKEILDIFYEV"
     gene            19646..20533
                     /locus_tag="KRH23_000195"
     CDS             19646..20533
                     /locus_tag="KRH23_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HHS5223495.1"
                     /translation="MAIYLEMPKLIHEFPFRTLSNEGEVLTTPHWHKEIEILLITEGV
                     VNLFINDKPMQLKKGEIVIIKGGDIHYILPSPGSERLVFQFDISFFNDLILLNEEKES
                     LINLFSSIKKCSRDWSAKIRKSVFDILIDIYNEDLYKIEGYSYAIKGKMYNLIPILYR
                     QIPREIEENTVEYEINSKEILERLNNIFKYVEKNYKQPIKLEDVSYEVGFSVYYFTKF
                     FKKNTGKTFITFLNEYRLEKAKWILLNNNISIVDLVEEVGFGSTKTFYRVFKEKIGVS
                     PLEFKKRYNSLEKKGSVSK"
     gene            20938..22386
                     /locus_tag="KRH23_000196"
     CDS             20938..22386
                     /locus_tag="KRH23_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HHS5223496.1"
                     /translation="MKLGKDFLWGGAISANQSEGFYLDGGKGLSQFDKLPLNDKRLKD
                     VCLDEDNILNENNQYYPSHIGIKFCENYKEDIAMLAEIGFKCFRFSISWSRIFPTGEE
                     SEPNEKGLQLYDNIIKELKKYNIEPLITISHFDIPYSLVEKYSGWADRRVVNLYVKYA
                     EILMKRYKDDVKYWIPFNEMNMIMHIPYIGAGLTFIADENQLQKKYQAAHHQLLANAK
                     TIEIGRYINKEFKFGCMLAAGKTYPYTCKPEDVFATLEHERHNLFFSDVQVRGVYPSF
                     MNYYLKSNQIKLIIKEEDLSTLKDNTVDFVSFSYYSSACSSARAEGLEKSKANGPETI
                     KNPYLPKSNSVWQNDPVGLRITMNQLYERYQLPLFIVENGLGTQDIVNEDGKIIDDYR
                     IDYMKEHIKNMILGVNEDGIELIGYLMWGCIDVTSVSEGKMTKRYGIIHVDSDDYGRG
                     SFKRTKKQSAFWYKKVIETDGEILFNDMETHA"
     gene            22412..24802
                     /locus_tag="KRH23_000197"
     CDS             22412..24802
                     /locus_tag="KRH23_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HHS5223497.1"
                     /translation="MSLIFTTKDQLIEQGFSKDTIKSNETLFTLANGHLGVRGNIEES
                     DFNNEYVDNMGTYVNGFYEESPITYGESAYGYAKQNQTICKLPNAHIVNFSIEGDYFD
                     LSKGITSEHSRILDLNEGILKRSFIWENSRGRKVKVSIERLVSQDIEELMMISYTITP
                     LNFNGKIKFKNKMENSMEKFNCEKVDDPRVASINKKQFKINVKKYNNKYFMNLVTERS
                     RLGLWCGFDSYITCGNITNETYNVSDECIEREIEVYAKKDERLNLEIVVGYSRVYSDL
                     NLNEERLKSLECLESLKCLESEAHLKSLELVLREACNIGFDKVKNIQRKKMNEFWTTS
                     DVEIEGDKTLQLGIKTNLFHIYQSAGRDGKTNISAKGLTGDGYEGHYFWDTEMYILPF
                     FIYTQPSIARALLDYRYSILDASRERARELGINKGCLYSWRTINGNECSAYYPAGTAQ
                     FHINADIAYGVRTYFEATNDEEFMMQNGLEILIETSRFWVEFGDYIESKNNKFCINGV
                     TGPDEYTAIVNNNYYTNLMAKYNLIYAVQMVDKFKHNLFSNEVFRKVKLQEYEVKNWI
                     NAAQNMYLPYDEEKKISKQDDSFLEKSVWDFKNTPKEKYPLLLHYHPLTIYRYQVNKQ
                     ADTVLSALLFPDEFSLEQKKRDFEYYEKITTHDSSLSRSIFGMMASEIGNHEKAYNYF
                     MDTALMDINNLQKNTSDGIHAANMGGTWMSLVYGFAGMKIKNDKLSFEPRIPKHWKNI
                     KFNILFRDNLVSVNIEEYKSYYKLIKGRNITILHDNEEIKLSKNIIEVNNCFKGSN"
     gene            24804..25475
                     /gene="pgmB"
                     /locus_tag="KRH23_000198"
     CDS             24804..25475
                     /gene="pgmB"
                     /locus_tag="KRH23_000198"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008801 - beta-phosphoglucomutase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HHS5223498.1"
                     /translation="MKAVLFDLDGVITDTAKYHFEAWHEIAKSLDIEIDETFNEKLKG
                     ISREESLDKILLSANKVDSYTKEEKLKVCEEKNNIYIKLINSLTYKDILPGINELIKE
                     LKKNNVKLGIASASKNAPRILESLGIKDEFDCIVNPSLLKRGKPYPDIFIEGSKILNL
                     KQYDCVGIEDSYSGIKAINAANMTSIGVGKKEVLGKCDHIVEDTSLLNYNTLLQAWSK
                     KINLA"
     gene            25514..26899
                     /locus_tag="KRH23_000199"
     CDS             25514..26899
                     /locus_tag="KRH23_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HHS5223499.1"
                     /translation="MKNKYEDVAQLIIDGLGGKDNIIDLTHCMTRLRFILKDEKKVNA
                     DKLKSIDKVVGVNSTSTQYQVIIGNEVGVVFNAIINKGINTTGDIKSDIKNKNKKNSI
                     LNNIIDTITGCMTPMIPALTASGMIKVILSLCTTFNWLSSNSSTYRVLDIIGDVAFYF
                     MPIILAINAAKKFNVNTSIAVIVVGVFLHPNFSAWVSSGDPISFIGVPIQGVIYAASV
                     IPALLTVWMMSYIEKFIDKLTPSMLKTILNPTLVLLISAPIALIVIGPIGNFLGEGLA
                     SIINLLQGRLGFIMVCLLAAAMPFIVMTGMHHALTPIFISAFATTGQESLILISQVCA
                     NLAQGGATLAVALRSKDSKMKQLASAAWISAIMGITEPALYGVTLKLKKPAMLASIGA
                     GIAGLFAGITHVTLYVPQNSIMAVLGLSGEKGISNIVNGLIVIFIALVAPFIMTYVFG
                     VEKNVKEGIDK"
     gene            27823..28857
                     /locus_tag="KRH23_000200"
     CDS             27823..28857
                     /locus_tag="KRH23_000200"
                     /inference="COORDINATES: protein motif:HMM:NF014273.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HHS5223500.1"
                     /translation="MANKIDNVKITDIYIDNNRLWKIYDRDLKPLLESIKEEGLISPI
                     AVQERSGKYKLIAGEHRLTACKQLGWETIPAQIIEREYEDNEIENARLTILEADENLK
                     RKYPDFIAEAHILTKRKEAYDKIVEYKTGGLTPEEYKKKIGGKVTSLLNSRTPLTDSE
                     LKELDFLEKDLVNVKTFAQNTIDSTGGSESNINSKLKIAKIIPNEKAKEIKANNISSK
                     TLTSIVVGVNEEEIKKASEIHLDTIKSIKIPEDSNINTLYQKAIKKTKYELKDKYFQR
                     NNPVEFAERVSEKIHEVIDIEEKKKENKIVQLTQNDLEYINTALALLKNAEKLSIIVD
                     DRIVFTKYIK"
     gene            28878..29927
                     /locus_tag="KRH23_000201"
     CDS             28878..29927
                     /locus_tag="KRH23_000201"
                     /inference="COORDINATES: protein motif:HMM:NF014273.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB N-terminal domain-containing protein"
                     /protein_id="HHS5223501.1"
                     /translation="MKTTIRKEKEIKIKEIYVAQRFKDEEDKANLDNLIENLKFHGMI
                     NAINVWEDHNGNYHLISGYHRLTACKILGKETIRVTIDTTKYKNEVDAYRNHRQENLH
                     ENGIRKHHTIYQLSKIFDELQVLYEQINPDNKFAEEEYLRARKREKMAKESLKGRKAK
                     EEQEYFKREIEKAKQIQEKTKSPLQRLIDDRGFSEVKAKQIQFINGLDKIMPNFSKKM
                     EASNISENRIWNLRKMFKKEDVIDQFKKINTTRDMNNWVSKLEGKKEGSKINVSEIAD
                     EGNGIVRLGTKHYVCYSDTEHLVRKFNFNIRMVVDDNDVAKAAIEVLGINHVKALIVC
                     TNDTAHELVLNAIKK"
     gene            30675..31043
                     /locus_tag="KRH23_000202"
     CDS             30675..31043
                     /locus_tag="KRH23_000202"
                     /inference="COORDINATES: protein motif:HMM:NF015898.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HHS5223502.1"
                     /translation="MELTKNEIEIMEVLWSEQRPLTRTEIVNLSVDKSWKDSSIHILL
                     NSLLKKNAIREAGYVRTGKGFGRTFEPTKSGERYYAGILAKIARKTSISMLFSKLIES
                     EDITDETIEELEELLKKKRE"
     gene            31049..32176
                     /locus_tag="KRH23_000203"
     CDS             31049..32176
                     /locus_tag="KRH23_000203"
                     /inference="COORDINATES: protein motif:HMM:NF017390.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M56 family metallopeptidase"
                     /protein_id="HHS5223503.1"
                     /translation="MLISGVSIYSFMSALVFSSFGLLLIAVLRNRNSFLIKNRTSLLL
                     LLLVLSIVRLLLPLDLYNTLLIESDTFLPWIQTVLEKTIFNDVTFGELIVIIWIVVAI
                     IFFVISMLSYIAEHRKIKIDFTIKDEQVEKIAKEEFAKNSVIKVSRNIDTPRVTGILK
                     AYVYLPPLSLGDNKLRYIIQHEIQHVKGKDILIKLFYTLLRSILWWNPVIHIFNSEVD
                     SLLELRCDLAVTKHMDYDGRMVYLQTILNVLKQTKNKREKFRLPSFCKNKNTQLIKQR
                     FEVVLNEESQKDIKEKLITICLALLLFIFSYFIILQPVSYPPQEELVSEVAITNENAY
                     LLIRKDGSIDLFVNGEFFGKVTNDDLEAQPISDIKNIRKEN"
     gene            32189..32428
                     /locus_tag="KRH23_000204"
     CDS             32189..32428
                     /locus_tag="KRH23_000204"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5223504.1"
                     /translation="MKSTMKKGIFGLLLVIMCVAGTDMVYASEVGIAIKTDSYKSVDT
                     KAEQLKWYYRIHNGKKQKRLWSITYGYWKTNWINV"
     gene            33001..35154
                     /locus_tag="KRH23_000205"
     CDS             33001..35154
                     /locus_tag="KRH23_000205"
                     /inference="COORDINATES: protein motif:HMM:TIGR04115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM peptide maturase, CXXX-repeat target
                     family"
                     /protein_id="HHS5223505.1"
                     /translation="MSKNYLMGCGNEQWKEGKAYEVTFIVTEDCNLRCSYCYEVHKNN
                     KKRMSFEIAKKSVDYILDNEELYDAPAVIWDFIGGEPLLEIELIDKISDYIKIQSYRK
                     KHKWLNDYRFNIGTNGTLYNQPLVSKYIRKNKDKLSISMTIDGTERKHNLHRIYEDGR
                     GSYNDVFKNIPKWLSDMPDSTTKVTFGSEDLIYLKESIIHLWNSGLKDVPANVVYEDV
                     WKDGDDKVFENQLISLADYVIDNKLWNEVNCTLFDENLGGPITDFNLKSNFCGTGRML
                     AIDANGDFYPCLRFSDFSLNDKCGRSIGNVNEGIILDKVRPFLALSTENISKEECIKC
                     EVASGCAWCQGSNYDCADNSSIYNRATYICKMHKARIRGNNYYWDRLKREHNIRRKIE
                     PKFKKNMYFILSDDSVEHCSYSSKSNSENIMSKELLKKALNYCEKNFFKPIILNSKTQ
                     ENIIDLDSFSVLSRIEIRDLKIKPTYKNTNEIVCLNIEDIDEYIGGRNCILNIYSSQI
                     NQIYISIKKLLEKSKRINLVFKGNINEIDLKLYEGELFKIKDLLIKLYERKQYKEVNV
                     ITDRIFLNKMDNCECGENNYAIAPNGNIYICPAFYFNNPEDFIGNIDEGITEDKLFNC
                     DMDHSPVCLACDAYQCNRCVYHNINCTGEYNIPGHKQCEKSHIERNTSMILQRLIKDY
                     KLPIDLEEDIKPLDYSDPIELILGELDVNPYASIK"
     gene            35176..35511
                     /locus_tag="KRH23_000206"
     CDS             35176..35511
                     /locus_tag="KRH23_000206"
                     /inference="COORDINATES: protein motif:HMM:TIGR04116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CXXX repeat peptide modification system protein"
                     /protein_id="HHS5223506.1"
                     /translation="MNLITTISKEDNETLINIVEEINTLRNLMITLTEENNLYKENSD
                     LYKQITEDIKEANHKYTLYWEMLIKKYNLNLELANKYTLNFSDCSIYLNEFDEDQMFS
                     DEGYKCENI"
     gene            35562..35717
                     /locus_tag="KRH23_000207"
     CDS             35562..35717
                     /locus_tag="KRH23_000207"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5223507.1"
                     /translation="MKLDSKNIETSVDPRWCPCKNGGCQFSCMKKCTGCLGSCEGGCK
                     GKVLIQP"
     gene            35761..35889
                     /locus_tag="KRH23_000208"
     CDS             35761..35889
                     /locus_tag="KRH23_000208"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5223508.1"
                     /translation="MKLDSKLVNDNINPRWCPCKGNCVASCKGTCILGCHGCVGTR"
     gene            36054..37772
                     /locus_tag="KRH23_000209"
     CDS             36054..37772
                     /locus_tag="KRH23_000209"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF012869.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHS5223509.1"
                     /translation="MVSEIKKIKNYKIFIKYIKPYKLRFIFLYLATILSNVADLFPIY
                     FLGKIINYVTEGKFDGIVKIICFLFIIFMINSFFSIIETYLTKWLIFRINQDIKADIY
                     KKSIELSIIDFNTLGSGHIISLIEGDSETISNFFVVKIVEVVIAIIKSIVSLFFLLYL
                     SIPLTIIAIISFPIGFLGYVICGKKINIKTSLLRQLGDELYSFLNNSLDGIKDVKAYT
                     MEQIMYKKFKNYIKRYRELNMEIAVLDIIVGFLNLFISSLTEWIIIGYGTWLIIYNKF
                     TIGSYVAFNGFLATFFDGIKSILNINLVYQTVIASIDRISNFFDISIDHSNRSLMISK
                     INGRILFDKVHFTYPNTNKKILSDFTATFEPKSLSVIVGLNGAGKSTLFSLIEQFYLP
                     NNGNIYIDNNNIRNIDLDNLRKNISIVHQRPVMINGTIKENLLYGDINATIEKINQVC
                     EKVDLAKFIEELPDRFDTILEELSGGQMKRIAIARALIKDPKILLMDEITSDLDGKNE
                     NEIMCLLDELSKEKTIIIISHRITSITNVPNIYVLDNGHIVDSGDHESLLKRCPIYSV
                     LINNQS"
     gene            37800..38468
                     /locus_tag="KRH23_000210"
     CDS             37800..38468
                     /locus_tag="KRH23_000210"
                     /EC_number="7.6.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHS5223510.1"
                     /translation="MKKMIIEVSNLSKVVDLLNTELTILRNIDLYIEEGEFVSIMGAS
                     GSGKSSLISILSGLDKNYTGNVKVCGENLSELTDDELAEYRNRKIGIVFQSFNLITSM
                     SVEENIKLPLIFSDNKEYKIVDKMIKKVGLTSKTKNNIKQLSGGEKQRVAISRALVCS
                     PNILFADEPTGSLDSTNSHAIMKLFKNINNEYGTTIVMVTHDIQMAEYSDRIISIKDG
                     TIIK"
     gene            38480..40981
                     /locus_tag="KRH23_000211"
     CDS             38480..40981
                     /locus_tag="KRH23_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HHS5223511.1"
                     /translation="MIFHEVYKIYSKNSLKNNKLLKISCIISIVFATAILLFTRVLTD
                     TYSSEVKRNMAITNGGDIKIQNIEYNKYYFTSEQIDKLEELKDKESIDFQLGSSMNTN
                     ILSNGMIESTELTVVNNIKMQNTYLKLRNENDIVLSQKTANKLNVNIGDKVFLKLHSS
                     VYDDTYFKVSDIIPKKFSLSTAQKEAEVGQEVVGESYVYLPNETKYNVAYINIINKEN
                     VKNIKNEIKNVFKNHFEVRTTDELEQSIIKRISMQLDSINLIGAISLLITGICLCSTF
                     IVFILNRIHDFSTFKALGIKKRSLSFLVFTELMSITIKGIIIGIILGIPITIFYINLQ
                     HINLFNISILSIIKNIFISIVIIIIETSIFSLIPISFVKKIPYEGINRDNSMLSSYKF
                     NFIPDIILVIFLTSISFTIYVKSFLGIFFILGLILLDLLVYSLIYALLKMVCLIKKII
                     KGKYSITFIYLNNDCKTNAFSSSLLTITIIFVLLLFMISEITFAMFSNYEVDNSIKNS
                     IVYQTTLEGKLITDKKLIENDIDYFQYYPIKIDSIESVNNISVNDYIEKIPYENRKDV
                     MNDLNDLSVDLFNTKQTILKSDLEYGNWFKENDKENSIIINNYLHRYLIDYKLGDTIK
                     LRINGKDIDFKVIGFLSPKSLNKGVDLGYININENISPKTLDLSKNQPVIYFFKEKLD
                     NTLLSKLLHNDKYANLEDYNDFAYSMKTYVDDQKSLLLNIIFAVSLSSILLILTSQII
                     IFIRRVLDYQIMYRVGMSKRKLIKIGLLEMIIVSIIQSILIAIFYELFRFLLISLLQR
                     DYNINYLLILIEFLVVLSINCFIFILAQRNIKLDL"
     gene            41495..42337
                     /gene="licT"
                     /locus_tag="KRH23_000212"
     CDS             41495..42337
                     /gene="licT"
                     /locus_tag="KRH23_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator LicT"
                     /protein_id="HHS5223512.1"
                     /translation="MIINKILNNNVVITLDDNDEEVIVMGKGIGYQKSKGNLIDKTKV
                     NKVFRISNKEISNKLQELLNNIPIEHMKLSSEIIEYAQIKLNKKLNESIYISLSDHTY
                     SAIQRMKEGINVKNAILWEIKRFYKEEFEIGMKALDIIENKTGIKLPEDEAGFIAFHI
                     VNAQLSEGHTLASDITKLIQEVLSIVRYHFRIEFHEESVFYYRFIMHLKFFAQRLLLD
                     SAHEGETDKELLSIIKSKYNKEFECVVKIKNFIKKQYNYILTDDELIYLTIHLAKVVK
                     DSNM"
     gene            42482..44410
                     /locus_tag="KRH23_000213"
     CDS             42482..44410
                     /locus_tag="KRH23_000213"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HHS5223513.1"
                     /translation="MGKYKQLAQEIVNNVGGKENISGLVHCITRLRFTLKDESIANDN
                     VLKNMEGIVTVMKSGGQYQVVIGNHVEAVYKDVVEIIGLDDSSTSSETKKSGNILDKG
                     IDIISGIFQPVLGIMAACGMLKGFNALFVAMGLYSDVSGGYMVINAAGDALFTFLPLF
                     LGYTSAKKFGLKPMLGLALGAAVCYPAIQGSSISAGADVMYTLFKGTMFASPVYIDFF
                     GLPIVSIDYTGTVVPIIFIVYFASRCEKLFNKCVPDLVKFFFVPMLTLLITVPVALIV
                     IGPIATFGSTLISQIVISIRDFSPLLAGAIVGFTWQILVIFGMHWGFIPVYINNVMTL
                     GYDNVMMPFFACTFASSAVVLAIFFKTKDKKLKEMAIPNFISGIFGVTEPAIYGILLP
                     LKKPFIISCIASGIGGAFYGFFNLRKFITGGMGIFELPAMIEPDGGMGNLIVALSGIA
                     ISMVVAFVLTMILYKDEKVEESKKVRNKGKEEIKEVKSTKLEREIVTSPIKGEVLKLS
                     DIEDAAFASGVLGQGVAIIPSDGKVVAPVDGVVTTLFPSLHAIGILSDTGVEVLIHIG
                     LNTIQLEGRGFEACIKQGDRITKGQTILNFDVDAIKELGYSTVTPIVITNSSQFLDVV
                     ETESKNIELEDNLITVLF"
     gene            44471..45898
                     /locus_tag="KRH23_000214"
     CDS             44471..45898
                     /locus_tag="KRH23_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HHS5223514.1"
                     /translation="MSFKNDFLWGGATAANQCEGGYNEDERGLANVDVCPTGKDRTAV
                     ITGKLKMFDFDDEHYYPAKTGIDMYHNYKEDIKLFAEMGFKVYRMSIAWSRIFPKGDE
                     ETPNEKGLQFYENIFKECKKYKIEPLVTITHFDCPMHLVKKYGAWRNRKMIGFYEKLC
                     KVIFRRYRGLVKYWLTFNEINMILHAPFMGAGICFEEGEDVEKIKYQAAHHELVASAI
                     ATKIAHEVDSNNLIGCMFAAGSVYPYSCNPNDVWEATKLDRENYFFVDVQSKGKYPNY
                     ALKYMEQKGITPEMEPGDIELLNKYTVDFISFSYYNSRCVRTDENADDMAEGNIFTSA
                     KNPYLSYSQWGWPIDPLGLRITLNHVYDRYEKPLFIVENGLGAKDIADENGYVEDDYR
                     IDYIREHIKAMHDAVSIDGVDLLGYTTWAPIDLVSAGTGEMEKRYGFIYVDRDNSGNG
                     SLRRMKKKSFEWYKKVIASNGEDLY"
     gene            46309..47085
                     /locus_tag="KRH23_000215"
     CDS             46309..47085
                     /locus_tag="KRH23_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HHS5223515.1"
                     /translation="MKYQHIIEVDKELCIGCGLCKNDCPVNNIIIENKKSVIKKQDCL
                     MCGHCAAICPTKAITLTGFDEPPIELTNKPKLDSDELLMAIKSRRSIRKFKDKEVSSE
                     IVKQIIEAGRYTPSAKNSQDVSYIVLDNKKSIYENEAVKFFRKIKPIANIAIKYSKEV
                     EIDNNFFFKHAPIAIMIITKDKISGSLAASNMALMAESYGLGVLFSGYFSDVANNSPK
                     LKKLLGLKRSNHVLTTLVIGYPDVKYRRTAQKEVATVRYL"
     gene            47101..47466
                     /locus_tag="KRH23_000216"
     CDS             47101..47466
                     /locus_tag="KRH23_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR/SmtB family transcription factor"
                     /protein_id="HHS5223516.1"
                     /translation="MEKECQQRMQEITSKFKECRKAISAMGDETRQLILIALLESDFN
                     GIRVGEITKKTHLSRPAVSHHLKILKEAEIVNLRREGTKNYYYLDSKKSQWKSLTELI
                     NLIFVGIQHISENDIRKGD"
     gene            complement(47632..48381)
                     /locus_tag="KRH23_000217"
     CDS             complement(47632..48381)
                     /locus_tag="KRH23_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440038.1"
                     /note="N-terminal region resembles flavodoxins. C-terminal
                     ferrodoxin region binds two 4Fe-4S clusters; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EFR1 family ferrodoxin"
                     /protein_id="HHS5223517.1"
                     /translation="MILYFSGTGNSRYVARKIAQELNDELISLNQLIKEEKTDELIST
                     DKPFIFVCPTYAWRLPIVVTDFIKETKFLGSNRVYFVMTCGGDTAKSINYIQKLCKYK
                     EWQLKGMAEIKMPENYIALFSTTDKETSKQMIKEADKQIYRIISDIRNENEFETITPS
                     GLGGTIKSGIINTVFYKTIISAKGFHYTDKCIGCGKCVELCPLNNINLKNKKPVWKNN
                     CTHCMACICGCPTEAIEYKNKTQNRERYYLE"
     gene            complement(48827..49384)
                     /locus_tag="KRH23_000218"
     CDS             complement(48827..49384)
                     /locus_tag="KRH23_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HHS5223518.1"
                     /translation="MRTLKYAILGLLNRNPMTGYDIVKEFNFQLAEFWNAKHSQIYPE
                     LKKLVNEKLIVYDIKISGDVLEKKLYTITEKGKDEFLKWLEKDEPMERTPKDIFRLRM
                     YFSNNLDIDTRLILLKHQLLQHQERITFLYSQMERYSEVPPLDSNDFGDYIVLDGAII
                     REQGAIKWLTNCINHHKNLDNTTLK"
     gene            49636..50904
                     /locus_tag="KRH23_000219"
     CDS             49636..50904
                     /locus_tag="KRH23_000219"
                     /inference="COORDINATES: protein motif:HMM:NF049980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015129 - lactate transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate MFS transporter"
                     /protein_id="HHS5223519.1"
                     /translation="MNLTQKRWIILIASCFINLCIGSIYAWSVFASPMAEYLNSLAGT
                     TFTAASLAIVFTVTNSVGPITMITGGMINDKFGPKKVVFVGGLIFGIGMILAGFSKGL
                     PMLILSYGIITGLGVGMVYGCTISNSIKFFPDKSGLVGGITTAAYGFSSVIMPPVTNW
                     IINKYGVTSAFKSIGLIFLIIVCVSSFFIKKCPADFTPEGWIPPEKKGKVRVVINKNW
                     KEMLSTPIFYLMIIILTCGAFYGLMCVSLASSLATNMIGMTSSDAAIVVSILALFNTF
                     GRIVAGYISDKIGRINTLSGALVISIFGLLCLLFSKEGDVATFYIGIIIIGICFGSFM
                     GIFPGFTVDKFGPKNNSVNYGIMFIGFAFAGYIGPAVMKNVYSVDGNYQRAFIIAIII
                     ALMGFILTFLYKYINKIQNLKIESLKIENK"
     gene            50920..52869
                     /locus_tag="KRH23_000220"
     CDS             50920..52869
                     /locus_tag="KRH23_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HHS5223520.1"
                     /translation="MERKYPNLCKPIKIGNVTFKNRMFSAPMGGTDITADCTIGSKST
                     AFYELRAKGGAGAVTISECMVHPETDGSHAYHLDLKIVDSLASFTYTADAIRRHGAIP
                     SVELSHSGQYSGTYLVDKDKKRGLSQWGVSPSVRPDGLKIKELTEEIIAEIVESYGNV
                     AALTKRAGFEMIMIHGGHGWLINQFLSPYFNKRTDKYGGSLENRVRFAKEVLDSVRKA
                     VGPGFPIEFRMSGSELFEGGYNLDYGIEIAKLLESRVDLLHVSAGTYQRGFAVTHPSM
                     FLEHGCNVYLAEEIKKHVNIPVATIGALNDPEMMEEIIASGKADVIYMARALLADHEL
                     PRKVMSNQDEKIVKCLRCFTCMAERATTSTRRCTVNPLIGRELDGTEVVPVLKPKKVL
                     IAGGGPGGLQAAITAVKRGHKVILCEKTNELGGILKGEQALPFKYEMYELGNTFGKIA
                     KDLGVEVRLNTTVTKEYVDNENVDALIIAVGSEPLVPPIEGLDGENVVIVNDYYLEKE
                     KVTDEVVVLGGGLAGCEAAIHLAQEGKTVHLVEMRAELAPDANIRHRPILLEEIERQG
                     IYVYTEHKGLSVTAEGVVCMNKSGNKINIPGTSVICALGQKPRREVVDTLLDCAPYVA
                     QIGDCVRASTITNAVYQGHHAALDI"
     gene            53133..53204
                     /locus_tag="KRH23_000221"
                     /pseudo
     CDS             53133..53204
                     /locus_tag="KRH23_000221"
                     /inference="COORDINATES: protein motif:HMM:NF013540.6"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            53526..54077
                     /locus_tag="KRH23_000222"
     CDS             53526..54077
                     /locus_tag="KRH23_000222"
                     /inference="COORDINATES: protein motif:HMM:NF015638.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CbrC family protein"
                     /protein_id="HHS5223521.1"
                     /translation="MRLFGKLKGVKAKNLCPQFRYQPFIYENGCVEWGKDICQCCGKK
                     VNKYINMIYSEQEVDCICLECIANGKASKKFNGTFIQDVEKVIDDEEKTKELFERTPG
                     YVSWQGEYWLTCCDDYCAYIGTVGIKELQEMGIVEEALAEYENRNERYENIRENLTKN
                     GSLCGYLFQCLHCGKYRLWVDAD"
     gene            54325..54729
                     /locus_tag="KRH23_000223"
     CDS             54325..54729
                     /locus_tag="KRH23_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3139 domain-containing protein"
                     /protein_id="HHS5223522.1"
                     /translation="MKKYKVIFIVLIIGIISVTGFVVYKNCIKPWKDAETYIDKYMVK
                     QDISKDNIKSITKEKAKKASYEGILYKVYYKDDPRYEYQYFYSDNYYALYVNKVMLQI
                     YDMENNNKLLRSNEELKSVKYPPIYLKYKPDK"
     gene            55375..56235
                     /locus_tag="KRH23_000224"
     CDS             55375..56235
                     /locus_tag="KRH23_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HHS5223523.1"
                     /translation="MKIIQILNNNVALVKRGKNEIIVFVKGIGFKKRVGQVINENEIE
                     RTYILDSYDMLEHFSYLLQNSDSNNIVLINEIIEYGEKALNIKSSDYLSLTLLDHLEF
                     LLKRCEKNQFIKSPLVWNVKIFYPKHFEIGMHALKLIGDSKGINLPDDEAVSIALHFV
                     NMEVNKESHDSTIVELRTLADIVSIIKYHFNVELDETSTNYMRFTTHLQYFIQRIMSD
                     EASIDEDNSIDLYKQVSQLYPKSFGSVQKIRKYIKSQFNVDISISEETYLMLHINRVT
                     QRLEAKSDEI"
     gene            56225..58096
                     /locus_tag="KRH23_000225"
     CDS             56225..58096
                     /locus_tag="KRH23_000225"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HHS5223524.1"
                     /translation="MKYKDLNENIIKLIGEKENIKSVAHCVTRLRFTLNDRSIAQTEE
                     IKKLKGVIDVVSNDVAYQIIIGTHVVDVYNEFMSMIGLSSSESSIKSERKKGIRGIKG
                     IFNSIFVVVSETMTSVIEVLLAAGILASILALLNMSGILQSDSPTYQILDTLRSATFH
                     FLPVLIAIASAKRLNVNPYIAVVLAVTLLSSSIDGVEGLSLFGINLQATTYANSFIPI
                     LLGVWAMGIIIEGLKKILPKALHYFLVPVLSLIITLSVTLTVFGPIGMWIGDGLNYAC
                     MFLIDTLGNWSVVALYAALQPLLIVFGAANFTMPISLNSVTTLGYDPIFMGAATISDI
                     AVCGAMFGYFLKTRNKEQKQLFGTVSFSALMGVTEPSVFGVFMKYRRAFVAVMIGGGI
                     GGLIAGLAQVKTYGMVWGLAALPTYLVGGEVSNFTFMIISVVVSFVAATAASYLLGIP
                     SDEKEEVKGDNEKELELIINENNSRTISIGNVAKGQVIALGEVNDKAFSSGALGKGVG
                     VIPSESKSTVISPVDGTITIVFPTKHAYGIVTDEGLEILIHIGIDTVNLDGKFFESLV
                     TQNQRVKKGDALAVFESDKIIEEGFDSTIITVVTNTSDYLDVISSNDESEELLTVIV"
     gene            58116..59570
                     /locus_tag="KRH23_000226"
     CDS             58116..59570
                     /locus_tag="KRH23_000226"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HHS5223525.1"
                     /translation="MNIKDTFFWGGSIAAHQCEGSWDSDNKGPAIMDFVTKGSYETPR
                     VITDKIEEKLDYPSHNGIDFYNRYKEDIALFKEMGFSALRISIDWSRIFPNGDDENPN
                     ELGIKYYEGLIDTLIENNIEPIVTLYHFELPMNLVHKYGSWNNRKLIDLYLKYSETVI
                     RRFDDKVKYWVTFNEMNHIDPQTEHSDIFTYMIAGIKYSEIENKVQTLANVGYNMTLA
                     GVKVAKLAREINPNNKIGCVFGLNPIYPYNCNPSNVLNAFLDNDRDYYQIDAMCNGKF
                     PQYKLKEYEKNNITIEVTDEDKKAFKEGKLDFIGLNYYFSSVSTPKENLSGDKSLFGG
                     IQNPYLEQSKWGWAIDPIGLRFTLNYIYRKYQLPILITENGLGAYDKIEEDGTINDDY
                     RIEYLSKHLSQMKSAIEEDNVECFGYLMWGPIDLVSATTGQMSKRYGFIYVDLDDEGK
                     GSFKRYKKKSFDWYKEVIKSNGEVLDFSTDIVVG"
     gene            60595..61803
                     /locus_tag="KRH23_000227"
     CDS             60595..61803
                     /locus_tag="KRH23_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5223526.1"
                     /translation="MENFWNPLTCFTVCVMIYAFSEFLSKKTKGAISTLLFVCIIFLL
                     GFWTNILPKDITGASGILAAMSNFGIALLITNLGTLINLEDLCHEWKTVVIALVGIVG
                     IGVGCLTVGSMLFGREYALIAAPPIAGSTVAGIIVTTVAEAANRPELAAFVILVLSFQ
                     KFFGIPITTYCINKELKFKRDNGDFLKDESKSNFKLPSMKIFKEDLGKKSSTLVYLAK
                     LSFVAMIGNFVGLATLIPGFTPANYYLNPNIACLLVGLIFTRIGFLEKGILDKSQSNG
                     IIMFGCMLMLPGGLAKVTPTALFGMIVPTIGILVVGSVFIILFTAIVGKLLGYSPRMS
                     AAIGVTCMLAYPATQIISNEGIDAMEGTEEEKQRATDYLLPKMIIGGFVTVTIASVAF
                     ASIIGPIIFG"
     gene            61834..63213
                     /locus_tag="KRH23_000228"
     CDS             61834..63213
                     /locus_tag="KRH23_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HHS5223527.1"
                     /translation="MIGSISINEIDKKRFKLDDLSKKIWENPEKAFKEFKACENTANF
                     LRSEGFDVEVGVGGLATAIRASFGSGKPVIGFMGEFDALPGLNQKVSTKQEAFELGAY
                     GHGCGHNLLCTAHVGAVVGLKREMLENNLSGTIVFYACPGEEQLTGKGFMARGGAFEG
                     LDLAINFHPNKISEATIGTSTAVNSVKFHFKGKTAHAGSDPQNGRSALDAVELTNVGA
                     NYLREHVTSDVRIHYTITDGGVAPNIVPDKASVWYYTRALSREAVESTYERLVKVAKG
                     AAMMTETEVEVEFLGGCYNTLNNHVLANLVSECMNEIKQEPWTREELDFAAELDRQSP
                     QQYKAMISKYNLPEGTHLYYGGGNVTNFNSYGSTDIGDVMHIVPTAYFFTGCTNLGAP
                     GHSWQFTSCAGSSIGEKGMIYASKIMAMFGAKILNNPEIAKKAKEEFDKSMNGKTYKC
                     PIPDDISTP"
     gene            63319..64509
                     /locus_tag="KRH23_000229"
     CDS             63319..64509
                     /locus_tag="KRH23_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HHS5223528.1"
                     /translation="MKNFFKEAQSIEGEIIRWRRYLHENPEIGCNLPKTVTFVTSTLE
                     KMGYSPKLASNNGIVAVLDSENGGKTLLLRADMDALPIMEETDLPFKSKNKDASHSCG
                     HDNHTAMLLGAAKILMDNKHLLKGRVKFVFEPDEETTRGAKSMIDDGILENPQVDAAM
                     AFHSMVGKFLNTGQVAYSRGPAMASADIFEITVEGKATHGASPEFGVDPINIMSHIQI
                     ALNTILSREKPQKEPVVLTIGMFNAGNVPNAIPNKASMSGTLRTFDQFVREKLKNRII
                     EISTGIAKSFGGNAKVEFKMGTPAVINDLDVGDEIVSYVKEVIGNENVIDFPSAMGSE
                     DFSEILLRVPGVFLWIGMGSISQGYNFGMHNPKAIFNEEGLVYGSALFAHCAVKWLEN
                     NFSR"
     gene            complement(64637..65965)
                     /locus_tag="KRH23_000230"
     CDS             complement(64637..65965)
                     /locus_tag="KRH23_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5223529.1"
                     /translation="MMKIAVITTEFLKEFVDNSIKKLNINAEIEIYIYRDFSHVGDLY
                     LEIEDRFDGFAVSGPIPKKAITKKAGTIKKPLVDFGTDLQSYYDMFLKLIFKYNTLDF
                     SRAYFDLTDWADNPKDISYYLSNGTFGDLMDSIDENASKMSLSDIAKLEKKIAKKHIN
                     LWNEGKIDFSTTRFSSIVPMLQNAGVNFHFIYPDIDLLKNTFNNLIKDIHLHRMKGNQ
                     PSVIYITVKDTNYDDSTLDQVYKILNSIKKDKLTDFIIEKNSNSFKIFTKCETIKSLT
                     KNFTACYIKESIENSTNIKVCVGYGIGNDIKQAMSSAISANKESKINPLNYSFLVNEN
                     YETIGPLLCDKLLTVSNKVTPHINTIAKSSKLSTLTIQKIISVTEILQRDEVTPKELS
                     SCLNVTVRTANRFLSSLLKSGNATILYEKQNSTKGRPERVYKLFISENKY"
     gene            complement(66583..67797)
                     /locus_tag="KRH23_000231"
     CDS             complement(66583..67797)
                     /locus_tag="KRH23_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HHS5223530.1"
                     /translation="MRNCIIAQSGGPTAVINASAVGIYEKNLETKYFDKVYFGINGIE
                     GILNKNIIDSDSLNKDNVLNLKQTPSSGLGSCRYKLADYKINSYDYDRVINILDEYEI
                     DTLFYIGGNDSMDTVMKFSQYCKNTTCKIKFIGIPKTIDNDLLGTDNCPGFGSAAKLI
                     STLIMETYLDFSIYKNNGIFIVETMGRDTGWLAASSSLARLNDTPLVDLIYLPEIDFY
                     EDKFIEDVRKIFKEKNKAYIVASEGIRDKYGNFICEQKTSAHDKFGHSQLGGVSNYLK
                     NLIVSSSITTRVKTLELGVIQRCAMHLASDTDLKQAAEVGAYGIELSKKGYTGVMAII
                     NRTCNNPYKYEVSHTDISKIANKTKYFPKEWINEECNYITDEALNYLYPLIQGKPDIK
                     YKNGLPYFSIIY"
     gene            68223..68939
                     /locus_tag="KRH23_000232"
     CDS             68223..68939
                     /locus_tag="KRH23_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004750 - D-ribulose-phosphate 3-epimerase
                     activity [Evidence IEA];
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HHS5223531.1"
                     /translation="MKHIKIAAGLAHVNYGHISAVVKEAMDAGVDYVHSDAADMHDLK
                     NMQLMGGHQIIEAIRPVTDKPIECHIYTRDCDRLFIEKIAAAGCNLLIIPAEHFLGAP
                     LAYIINYCREFGMKVGLTIGCYTPLCFVDEAIYDIDRLQIVVHGVDETDGKDNWGWRK
                     SAVDLVKRARKMIDEKNPKCELAIDGGLRADNMEPLIECNPDVVILSSAIFKDKDGIT
                     AGVKNCRKAIDEAATKFGLE"
     gene            69074..69700
                     /locus_tag="KRH23_000233"
     CDS             69074..69700
                     /locus_tag="KRH23_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HHS5223532.1"
                     /translation="MKKEMIKDYLLITISAFLMALAVNFFFAEHTLAPGGITGLSVVL
                     STFLSMPVENISLGISMPLLVMGLLFLGKGFGIKTLYITLMGPLFLKVIPQTHITDNL
                     LVAGVIGGLLVGTAIGIAIIRGCSTGGTDLVAMLINKVIKFLKLPVILFMLDGFIIVA
                     SGIISKNFMISIYSLISLLLIIKTIGFVTTKFGKNTEEINNINNACAQ"
     gene            complement(69900..71444)
                     /locus_tag="KRH23_000234"
     CDS             complement(69900..71444)
                     /locus_tag="KRH23_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HHS5223533.1"
                     /translation="MNKRLLDIAELLLNSSDYITVDTIAEELKVSNKTIRNDLVILDE
                     WLLEFNLSLDKKTGSGVIILGNEDIKLKVIRDINDKSNCIYAYSPEDRKRYILSKLFI
                     KNSKFRIRDICNELHVSRATVHKDLVVIQNFLQNFKVTLVRKTNNGVYLEGKEKDIRK
                     AIFELATVNKSYTELKEILFSKSNECKDTPSTKIFKELFNYDFEKLSQITLHTLQVEK
                     SNLSDEYYINFLIHIAICIKRISIKRYINLSEGFFRELLEHEYFEKSKILCVNLSEAF
                     DVEFIDEEVCYILLHIEGLLKSIKKTTTLEPLKNEEITEYNLSEAIAVHWGSILNLNL
                     KDDLILIKSLANHLKSVLHRINYGFTITNPILNDIKRTFPYTYKAAKESNTVIKQLMN
                     YEVNDDEIGYLALYLISAIDRSKSPLNTILICHCSDGVSNLLVQKLSFEFNQINIVKS
                     IPLSSISFTNFDDVDLILTTAPVDFEHNAELININALLSKNDISRLSTIIKKLYSEKN
                     KILSYK"
     gene            complement(71470..72111)
                     /locus_tag="KRH23_000235"
     CDS             complement(71470..72111)
                     /locus_tag="KRH23_000235"
                     /EC_number="2.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transaldolase family protein"
                     /protein_id="HHS5223534.1"
                     /translation="MKYLIDSANLDEIQKCLKYGFKGITANPSMYLKEKVNFHEFIET
                     CANLNPEILTAEVIGNNLYELINSCDKILNINKNTIIKINFSEVGLELINILNSKGIK
                     TACTLIFNVNQASLAINAGADYLFPFIGRNDENGNDGIKSLTEICNLISINGYNTKVV
                     AASIKNVFHLTQASLCGCDYAAVTYDLFKKASFNQLTIDGANTFERDWSKVNK"
     gene            72381..73532
                     /locus_tag="KRH23_000236"
     CDS             72381..73532
                     /locus_tag="KRH23_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HHS5223535.1"
                     /translation="MINFYQPSRINFGQGTLSELPRIIGKYGKKCLLVTTPNVEPLDK
                     LYKRVTLNLIEKGIEVVHFDRVEPNPTVELINEGFELAKKESVDVVLAVGGGSSIDTA
                     KVLALTFGLEKIDWDYMFSTYTNPFKIYDKVSEKELPLIAVSTTSGTGSQVTQAAVIS
                     RGSEKNTIFHQNCFSKECIVDPELMLTLPERITASTAFDAFTHAFESYINPNANDFTE
                     IMSEKSMELVINYLPKVMEDKNNIEYRTKLAVADTLGGSSLANAGAAAPHPLSEIIGG
                     VTHIPHGEALAIVFPKFAEKFYKDNIEKFAKVARMLNQELEKVEDDEAAKTLGNEIES
                     FLKRVGLKTKMSEFNVTKEQLEQITSCPVLGFLPFGKKEDLVEILEKSY"
     gene            73545..74357
                     /locus_tag="KRH23_000237"
     CDS             73545..74357
                     /locus_tag="KRH23_000237"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HHS5223536.1"
                     /translation="MRYKLICTDMDGTLMGKGFEVSEENIKALKEVMEKGIKVALVTG
                     RPYNAMKYFTSVLGDDIYIISTNGTYFKLLGYEYKKVLSKEALKKIYTIGEKYNLNKH
                     FKGCKIVISNNEIGEEHPYRLINSKNKEEDRIEIIENASCETLLEKADNEILKCILFS
                     ENVDSLREAKEEFKKQEDLEVVSSGKINFEVMSKGTSKGIAVKKFCDILGIDSEEVIC
                     IGDNENDISMIKFAGLGIAMGNATDEVKSMADFVTDTNVNDGVAKALRKILS"
     gene            74383..74874
                     /locus_tag="KRH23_000238"
     CDS             74383..74874
                     /locus_tag="KRH23_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HHS5223537.1"
                     /translation="MFNIFKKKENKIEKIYSPFKGNLVNLEDVPDAVFAQKMMGDGVA
                     IIPSEGKLYSPVDGEIVNVFDTKHAIMIKSNDNTNILIHVGLETMSLEGKPFDVKVKA
                     GDKVKAKDLIMEVDLDFITSNDLNIITPVVIMDDADSVKRTVKDRIEPGNVDINSIIM
                     EVE"
     gene            75139..76542
                     /locus_tag="KRH23_000239"
     CDS             75139..76542
                     /locus_tag="KRH23_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HHS5223538.1"
                     /translation="MIVNKELIIDYLKSNQENIINDIRSLVEIPSIRDESTTDINQPF
                     GIEIRNAFDKLIQIAKDKDFVVKDFDGYAIHIEYGEGEEVVGVLNHIDVVPIYNKEFW
                     KSKPFKVCQKDNYLYGRGVNDNKGPLIGILYALLFLRELNEKPKRKIRLIVGGAEETT
                     WECMEHYFSVNEQPKFAFSPDGNFPIVNGEKGILYFNLRKKIDKDKFRNHNLVDIKSN
                     KEDGFVCDKIEAVFKTNDKKDLVESLAYYTEIEELEEGKVLVRYTGERALSRNPHRSY
                     NCAFSLAKDLEKIKKLNDKGVIIRDILNSYFTDDNHGKKLGIYKEDVDMGVSTICIMS
                     IFLEKNELNMKIDFRYPKGISWEFITNRINEIGKKENLIVDIYKDLKLLYVKPDSELI
                     NKLSNAYKQGFGKEAELFTKGAASYARVLKNGVAFGPTIEGDNPNSHQANENISIDTL
                     YKAIEVYIYALYSLAFQ"
     gene            76562..78214
                     /locus_tag="KRH23_000240"
     CDS             76562..78214
                     /locus_tag="KRH23_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HHS5223539.1"
                     /translation="MKDKLQVLSGAMMIPVILLVVAGVFIGLGSAFANMENVSALGLS
                     GLIKEGSFINVFFKVINDLGFMVMRYLPIFFVTGIAFGLSKKEKGWGALGGIVLFIGM
                     HTVISTLLAANGINSDTVTAEAFMASGLGEAEAYSRSSLYGSFLGIFSYDCSIFGAII
                     AGFVASAVHNKFVDIELPSALSFFSGPRFSMIMMFIASIVLGTAMYFIWPPVGLALSK
                     LGNWIGSSGLLGTFTFGAMDKALLPFGIHHLIAFPIEYTRVGGTMEVGGAIYEGVNNI
                     RLAQMGDPDTLSYITRNFTTGRLLIHFAILPAAALAMYKLADNANKKKAISILIPAIV
                     TAMLVGVTEPIEYTFLFVAPLLYFVAYVPLAGLTYVFTEMFNVSIMGESFRNMFPNLL
                     QPQKVDALPLLFLIPIFFIVTYIIFTWAIKKFDIKTPGRSSEEVKLYSKKEYRERQSV
                     DAGKTAYNNAVEEEVDDKDTKLVHSIIEGLGGSNNIKNVTNCATRLRVELNSIDGFYE
                     DGFWVNELGASGVVKKKNSVQVIFGPRVITIASKLKAVLGVD"
     regulatory      78486..78665
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00168"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Lysine riboswitch is most abundant in Firmicutes
                     and Gammaproteobacteria where they are found upstream of a
                     number of genes involved in lysine biosynthesis, transport
                     and catabolism; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="lysine"
                     /db_xref="RFAM:RF00168"
     gene            78809..80200
                     /locus_tag="KRH23_000241"
     CDS             78809..80200
                     /locus_tag="KRH23_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HHS5223540.1"
                     /translation="MSSLKKKKFTMPQTLTIIFLLIVLMAILTWIVPSGNFERVDIDG
                     RSVVVAGTYEKAPSNPQGITDVFTAPINGFIDAAEVVGFVLIVGGAFGIVNKTGAIEA
                     VIAHTVNKMKKFQFLIIPISMILFGLGGTTFGMSEETLPFYMIFIPLMTSMGYDSLTA
                     VATVFIGATAGFGAATTNPFSVGIAQALSQIAPGSGIEFRVVMFIIYMAISIGFVMMY
                     ANKVKKDPKKSLVHDISLNQESMVNSDTNIKEFTKREAMVIAIFTIGMAIMIYGVLKL
                     GWYITEIAMIFTAIGIISGIASGLKQDDIVNSFISGAGDLMTAGLCIAFARGIVIIAE
                     NGFIIDTILNSAANLLNGLPKTIFINLTFLIEGLIAFLIPSASGLASLTIPVLAPLGD
                     LVDVSRQMIVTAYQFGIGVTNLITPTSGVLMGALAVANIPWSKWVRFVIPLMVVLTIL
                     VMAFLTIGLYLGF"
     gene            80214..81401
                     /locus_tag="KRH23_000242"
     CDS             80214..81401
                     /locus_tag="KRH23_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HHS5223541.1"
                     /translation="MIESIKKRAYEIENELGKEIEEVCNFIFNNPELGEEEYISSKYL
                     VEKMKEYGFDTVYPYCNMETAFRAELGDNDGPTIAFLAEYDALPGYGENKEPAHACGH
                     NWIAASTIGACIVLSKLKENFKGKIVLIGTPAEETTGGKCDLVKAGAFDDVDVSYQMH
                     IEAFNNINCKALAIDSLEFSFEGVSAHAASHPHMGVNALDAVQLTFAGINALRQHVKS
                     DVRIHGIVSNGGEAPNIVPEKAACKFFVRAAERSYLDEVTKKVINCAKGAELMTGAKL
                     SYRYFENSFDNIINNKVLQKITKNNLIEAGITDILEGKDGPVGSTDIGNVSQVCPTMY
                     TEIALDISPMVYVHEKEFLNYANSEEAYDKLHKAVKAMVGCALEIYLEDGLLDEIKKN
                     HLN"
     gene            81752..82612
                     /gene="licT"
                     /locus_tag="KRH23_000243"
     CDS             81752..82612
                     /gene="licT"
                     /locus_tag="KRH23_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator LicT"
                     /protein_id="HHS5223542.1"
                     /translation="MIIEKILNNNVIITTDENHKEIVVMGRGLAYKKRTGEHISKDKI
                     DKIFKLSDPNISDKFKELIADIPIRYMELSDEIILYAKEKLGKRLNDSIYISLTDHMY
                     TAIERAREGVSVKNVLLWDIKRFYKSEFKIGLEALDYIEKKFEIRLSEDEAGFIALHI
                     VNAQMDQSIKTIYEITQIIQEISNMVKYHYRIVFDEDSVYYHRFITHLKYFAERIVSN
                     NLHENNEDDLLNVIKVKYKNAYKFIEKLDEFIHKKYNYDLTDEEKLYLTIHVERVVSK
                     SIKSDINPNN"
     gene            82686..84602
                     /locus_tag="KRH23_000244"
     CDS             82686..84602
                     /locus_tag="KRH23_000244"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HHS5223543.1"
                     /translation="MRKYEQLSKEIIANVGGKDNISSLSHCITRLRFKLKDESIANDD
                     VLKKMDGIVTVMKSAGQYQVVIGNHVPDVYEVVCDLAGLGGDTIDNSDSDAPKGLLNK
                     FIDIISGVFQPILGVLCAAGMIKGFNAVFTALGLYGETDGAYIMLNAIGDAMFQYMPI
                     ILGYTAAKKFKLKPFIGMLIGAVLCYSGIQLDTLASTGQPLYNLFTGTIFESPVYITF
                     LGLPVIAMNYTSTVVPVILIVLLAAKLEKVFAKIIPDVVKNFFVPMAVLLVSLPLGFM
                     VIGPIATYASNIVGNGFLALFNFSPILCGALTGLLWQVLVIFGLHWGLVPIAMSNLMT
                     MGFDTILVGAFVPSFAQTAVVAAMYFKLKDKKIKELCIPAVISGICGVTEPAIYGITL
                     PRKTPFIYSCVGGAVAGAVMGIMNVKSYVMGGLGIFGIPNYINPTTGDMKGVYATIIA
                     IIVAIVVGFVLTLFFWKDDAIVEISKDDNGQGVIEKNKREVVYSPIKGEVKALEQIQD
                     AAFSTGILGKGVAITPKEGKVVAPFDGTVMTLFPTKHAIGIISDNGCELLIHIGLNTI
                     QLEGKYFKSFVNQGDKIKKGQTLITFDIESISKEGYCLETPVVVTNYSDYVDIVENTQ
                     KHVNNSQELITVLA"
     gene            84689..86113
                     /locus_tag="KRH23_000245"
     CDS             84689..86113
                     /locus_tag="KRH23_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HHS5223544.1"
                     /translation="MALRKDFLWGGATAANQCEGGYKEDGRGLANVDVTPQGKDRFPV
                     LAGKMKMFECDDEHYYPAHEAIDMYHNYKEDIKLFAEMGFKCYRMSIAWTRIFPTGVE
                     DVPNEEGLKFYEDLFDECLKYGIEPVVTICHFDVPMYLVKKYGAWRNRKLVDLYVKYC
                     EVIFTRFKGKVKYWLTFNEINMILHLPFIGAGLYIEEGENEEQIKYQAAHHQLVASAL
                     VTKLAHNINQEFKIGCMLAAGNTYPNTCNPLDVWKSIEKDRENYFFIDVQSRGEYPTY
                     ALKELERKGINIVMEEDDKKILKENTVDFISFSYYSSRLTSADPKVNILTEGNVFASL
                     KNPYLDASEWGWQIDPLGLRITMNSLYDRYQKPLFIVENGLGSVDNPDENGNINDDYR
                     IDYLRAHIKAMIDAVELDGVDLWGYTPWGCIDLVSASTGEMKKRYGFIYVDKDNDGNG
                     TLKRSKKKSFAWYKKVIESNGEEL"
     gene            86129..87562
                     /locus_tag="KRH23_000246"
     CDS             86129..87562
                     /locus_tag="KRH23_000246"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HHS5223545.1"
                     /translation="MSFKKDFLWGGATAANQCEGAWNLDGKGPSCSDMCTGGSQKVSK
                     RITRVIEKGTFYPSHEAIDFYHRYKEDIALFAEMGFKVFRFSIAWTRIFPTGMEKEPN
                     EAGLKFYENVIDECLKYNIEPLITISHYEIPFAITEKYNGWVSRDVIDLYMNYCETIF
                     KRYKGKVKYWLTFNEINSATMPMGGYLSQGILNEGTTDFINQVDIPQLRFQGLHHQFV
                     ASAKAVKLAHEIDSNYQVGCMQIFATMYPYTCNPDDAVKTQRDSRVMNYFCGDVQVRG
                     EYPTYMNRYFGENNIEIKMEKGDLEILKEGCVDFYTFSYYMSTCVSSDSKEDNTSGNI
                     LGGVKNPYLKSSEWGWQIDPEGLRYALNEIYDRYRIPMMVVENGLGAYDKKESNGVIN
                     DDYRIEYLKAHIEQMKEAVEDGVDLFGYTPWGCIDLVSASTGEMAKRYGFIYVDKYDD
                     GSGDLSRIKKKSFDWYKQVIESNGERL"
     gene            88000..90009
                     /locus_tag="KRH23_000247"
     CDS             88000..90009
                     /locus_tag="KRH23_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54 interaction domain-containing protein"
                     /protein_id="HHS5223546.1"
                     /translation="MKTIAVVTDGLSKLECFLNKNLEMIFKDKVMIKNYYLNKITEKE
                     LIKDDIILVMIDDRVLKIKKYVEDVSKIITINRSIKQKDIYKLFSLPEGIDVLVVNDN
                     KHTVLETISNLYNIGINHLNFIPYNPNEEYRNIKIAITPGEASLVPKYIEEVIDLGHR
                     YIDSSTFIQIIAKLKLDDKEITERLIKYTDEIISLYSGINTKYKELTIKADELNSIIN
                     LSNLGMAMVSDKGNIIICNNSLGDILDIQSNIIGKNIDELENENIKKIFSLSKAHDEV
                     IKFNNKYLNVNKYNIESFGRVTGYYFCIQEITYIRKLEQNLSKKLREKGQVARYTFDD
                     IKTVSTKMERTKKLGMKIAESDYTILITGESGTGKELMAQSIHNASPRHSQPFIAINC
                     AAMPENLLESELFGYEEGAFTGALKGGKKGLFEQANNGTIFLDEIGDMPIYLQSKLLR
                     VLQENQVMRVGGENVIDIDVRVIAATNKNLLEMIKGDRFRADLYYRINVLPINILPLR
                     ERKEDIEVMLKHFMKRKRAISQDVQDIINAYEWPGNIRELKNTAMYINIMSSEDVILI
                     NDLPHNLLNITEDFSKEISILKDRTSIEKVKLVMECLKNANNLNKNIGRNGIVNSINE
                     LGYNITEGEVRGILNMLKELDLIICESGRKGSELNRRGKNILNSI"
     gene            90253..90999
                     /locus_tag="KRH23_000248"
     CDS             90253..90999
                     /locus_tag="KRH23_000248"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0016811 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds, in linear amides
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HHS5223547.1"
                     /translation="MKKLVKKKYPIIGISGNLLIDEGGMFPGYERAYVNNDYIQSVVM
                     CKAIPYIVPIVYDEEIIKEQVSNIDALILSGGQDVNPLIWKEEPHNKLEAISPKRDSF
                     DMKLLKHALDMKKPVLGICRGEQIINVTEGGSLYQDLSLIEGAYIKHNQKHLSNVPTH
                     TVQIKEGTKLYEILGEKEVLVNSFHHLVVNKVAPGYIVSATSKDGLIEAIEKEGSEFV
                     IGIQWHPEMMTRDYDNMKKIFMAIVKEASK"
     gene            91040..92359
                     /locus_tag="KRH23_000249"
     CDS             91040..92359
                     /locus_tag="KRH23_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015171 - amino acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HHS5223548.1"
                     /translation="MEKGIKLGFWSIVLLGINAIIGSGIFGLPGDAYTDIGPASILVL
                     VFCMLLAVSIALCFAEAGSWFDTDGGPYLYAKEAFGDFVGFEVGFMKWIVSMIAWATM
                     ANFFAVTLSSVWPQAAEPLTKNIIIGILVVGLGIINFMGMKQSKHLNNIMTIGKLLPI
                     VLFIAVGLFFIKGSNFTPFVIIQKGQSASSAFVAVSITLFYAFTGFESLAVAAKDMEN
                     PKKNVPKALVMVMFVVSIIYMLILGISIGVLGNGLAGSATPVADAAIKMLGPIGGYII
                     TIGTIVSVGGINIASSIFTPRSAAALVEQGLMPKSIRKTNKNGAPYIAIIVSVIGILL
                     IAWSGSFTTLSQISVVSRFIQYIPTCLAVLILRKKYAGKVVNFRIPGGAIIPIFAVII
                     SILLLIKAGIDEPMKIVWGLGGMIIVVPIYFYMTKVYSKKYNDVEVK"
     gene            complement(92455..94122)
                     /locus_tag="KRH23_000250"
     CDS             complement(92455..94122)
                     /locus_tag="KRH23_000250"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HHS5223549.1"
                     /translation="MKNWWKKATVYQIYPKSFKDSNNDGIGDINGIIEKLDYLYSLGV
                     DLLWLTPMYVSPQRDNGYDIEDYYNIDPKYGTMNDFEKLLKEAHKRDIKIMMDMVLNH
                     TSTEHKWFKESKKSKDNPYRDYYFWKDAKPDGSVPNNWISRFSGTAWKYDETTNQYYL
                     HLFEETQADLNWENEKVREECYKILEFWADKGIDGFRLDVVNLLSKTPGLPDDPITGP
                     KGDGRTHYADGPRIHEYLHNMNQKVFKPKNIVTVGEMSSTTPEECINYTRENREELSM
                     VFSFHHMKTDYKGGAKWTNEMFSLDKLKKAQSDFQYKMYEGKGWNALFYSNHDQPRAL
                     SRFGDDRFFRQESAKMLAITLFGLQGTTYIYQGEEIGMTNAYFTKIDEYDDAESKNAY
                     YHMIKSGIDEKEALLILQQKSRDNARTPMQWDNTIYKGFSNHKPWLKVNNDNISVENE
                     LNDSRSVFYTYQRLIKYRKQYDIFTEGTYRLLDENHKNLFVYEREYKNQNLLVISNFT
                     HDNVVYKLPETYLNKLNYTILETNYTRDIIENKMEIKPYESIMIYYK"
     gene            complement(94319..95041)
                     /locus_tag="KRH23_000251"
     CDS             complement(94319..95041)
                     /locus_tag="KRH23_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HHS5223550.1"
                     /translation="MAKNKFSEIYEVLKEEILDGKYTSNMMLPTELQLIERFSCSRNT
                     VRRAISQLNTEGYVQSIKGKGVVVLENSCSNDFFLNMHNFKGVESIVEDKKVNTATSV
                     LHFSKILIDNKLSKKTGFKVGSEVYYLHRLRYIDNIPKILDINYFLCSIVRDLDVSIA
                     QGSIYKYIEECLGTKIVSSRKIFKIEKATELELKTLPLNDYNCVGVIKNSVYTDDGKL
                     FEYTESKHTPETFVFMDVTQRY"
     gene            95411..96859
                     /locus_tag="KRH23_000252"
     CDS             95411..96859
                     /locus_tag="KRH23_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HHS5223551.1"
                     /translation="MKRFLNKMMQQLSLLGKTMLVPIAVMPAAGILGLLFGPNMLNVP
                     AISNISNIVFSNVDYLFLLGAASAYSKSKDKTSVMVAAVVAYMIFKSNLELLNDTLNA
                     GVFGGIIVGACIAWTYNKTYKVKVPAFLSFFAGEKCVITLSPVVALILSYIFSLLWIY
                     PQAAMNQFGFWLGGAGAIGIFLFLFCNRALIPTGLHQVLNAYILFEMGEYTTSTGEVI
                     RGEIPRFMAGDPNAGFFWTGFYIIMMFSIPAISYAIYKTAQDKKKQEVKGAMTAGALT
                     SFMATVTEPIEFSFLFASPKLYIIHSFYSGLGGVVLYLLGARLGSFNGASIIDYVLSF
                     SYGDKAWLVIPVGVVFFVLYYVTFKYIIIKDNVQTPGREVEIEIGDKVSEKEKNLKLS
                     HGNFSYMAKQIIKNCGGYENIVTLNNCMTRLRLEVKDATILNDDNIKKTGAKGVIKLS
                     NTSVQIIIGTDVVKVKDEMEMQLDELRKQADA"
     gene            96861..97631
                     /locus_tag="KRH23_000253"
     CDS             96861..97631
                     /locus_tag="KRH23_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ChbG/HpnK family deacetylase"
                     /protein_id="HHS5223552.1"
                     /translation="MKKLVVRADDIGYSEGVTLGIISSYKNGIVTSAGIMVNMPFSRQ
                     AIEMVKNDDVCFGLHVNLVIGEPCCKEHIKIKNLLDEGGKFVSSKIRRTQLLTGKEVF
                     NYEEVYEEVCAQIETYKLYMSKLPEYIDIHGIEEDVSISAMCDAAKEYGIPSCPYYLD
                     SCISMPSKYPQNDFYKLNKSFVKLFEEKYINLDKDITLMVTHPGFIDYSLIKSSSLIQ
                     ERVYEHAMLCDKEVKMWLKRNNIELVDFKDIFKSNNYI"
     gene            97864..98619
                     /locus_tag="KRH23_000254"
     CDS             97864..98619
                     /locus_tag="KRH23_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HHS5223553.1"
                     /translation="MNNKIDGGETMEFYERAKKYEYKFTDTEDMIIEYMRKNKEEIVK
                     LSIQSLADKFFTVPNTIVRLCKKMEYDGFSQLKNNLKEELKNEDKEPKNGFESDIKKT
                     LELIDYEKINKVADIIQKSRSIIVYGIGQNIPLCEILVKEIRGGHDNITYYSQRHEVL
                     HDIGKLGEQDMFFALSLSGETKEVIEVAKTAVNKGCKVVALTHICENQLQQIADISLY
                     CYSTIKQVNGYNISDKVPIMMIMRAIIEQYWLR"
     gene            98749..100674
                     /gene="mngA"
                     /locus_tag="KRH23_000255"
     CDS             98749..100674
                     /gene="mngA"
                     /locus_tag="KRH23_000255"
                     /EC_number="2.7.1.195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005351 - carbohydrate:proton symporter
                     activity [Evidence IEA];
                     GO_function: GO:0022877 -
                     protein-N(PI)-phosphohistidine-fructose phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS 2-O-a-mannosyl-D-glycerate transporter
                     subunit IIABC"
                     /protein_id="HHS5223554.1"
                     /translation="MEFKKITNENLVFLKQKIKTKEDAIKFLARKLYDEGKLTSYEEY
                     LEAVMYRETLSPTGFERGLAIPHGKSKSVKEAAFAAMTLETPIENWESVDPNNKVELI
                     FLIAVPENKGGNTHIQILSELVTRLSNEDYMNMLLNSKTKKELFNNLDIKEKKEQIKE
                     EIRIQNESKKIVLAITACPAGIAHTYMSAEALIKAGKEIGVDVYVEKQGANGMVDPHT
                     PDIIKRADAIIYATDVAPKNTERFEHLPNIKTSVAAPLKRAKEIIYEALEVAQKQGKG
                     DYIEKSSDISYCEKSSWKKDVKSAILTGVSHIIPLIVAGGMILAFAVLASQAFGLQEL
                     YNQEGSWLWQLRKLSGGMLGTLMVPVLSAYMSYSLAEKPGLGPGFAAGLAADLIGSGF
                     LGGMLGGLLAGYIVKFLKKNIPAKGTLAGFVSFWVYPVVGSLVVGLLMLFVVGKPVAA
                     LNNSLINWLNGMTGVNAILLGAIIGAMVSFDLGGPINKAAYTFAIGAIASGNFIPYAI
                     FASVKMVSAFGVTIATVLGRDLFSESEKEIGKQTWILGLAGITEGAIPFMIEDPIRVI
                     PSLVAGSAITGSIVAFFNIGLQVPGAGIFSLALLEGSMSGFIIASIWFFAAVLGAIIS
                     AILLIITRKQKNQRKIH"
     gene            100818..103433
                     /gene="mngB"
                     /locus_tag="KRH23_000256"
     CDS             100818..103433
                     /gene="mngB"
                     /locus_tag="KRH23_000256"
                     /EC_number="3.2.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004559 - alpha-mannosidase activity
                     [Evidence IEA];
                     GO_process: GO:0006013 - mannose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannosylglycerate hydrolase"
                     /protein_id="HHS5223555.1"
                     /translation="MKKNVHIVPHMHWDREWYFSTEESRILLVNNMEEIMDMLENNHN
                     YPYYVMDGQTAILEDYLAVKPECKERIKKLVQEGRLIIGPWYTQTDEMVVGGESILRN
                     LLYGIKDCDEFGEYMKIGYLPDSFGQSAQMPQILNGFDIKYSMFWRGCSERKGTNKTE
                     FNWKSDEGSSVLVQILPLGYAIGKYLPMNEDELRTRMDKYLPVLDKGATTDHIILPNG
                     HDQMPIQKNIFEVIYKLKECYPERKFFLSRYENIFKELEKNEDIDTIKGEFLDGKYMR
                     VHRSIFSTRMDIKSANARIESKITNILEPLASIAYSLGFEYHHGLIELIWKEIMKNHA
                     HDSIGCCCSDKVHQEIMNRFFLAEEKVDQLITFYKRRIVDAMSCEMALDKLVAFNLMP
                     YDRNEIVSAQVITKMKAFEIFDKDNNKLDFEVVHKEVIDAGLIDRQIVHYGNYDSFMV
                     YTINFKDKIPAMGYKAYMIKEVEHMLEKAYEVCDMVDNDFYTIQVNENGTLKIFDKKL
                     NKTFENVLLMENGGDEGDEYDFSPLPNEKLIFNDNIVANSTIKKNRFNNEIKINYRLK
                     VPKDIQARKNNRADSFIDFDIVINVPNDKAIIDVVFNINNQARDCRVRTYIPTNIASK
                     FSVSDNQFGHIKRSVYDDAMEVWQQEEWSERPDSIYPMLTFVGLSDKEHGVAVLTNST
                     REFEIVGEKFDTIAITLFRSVGFLGKEEMARRPGRPSGIKLPTPDSQMIGDIKIDLAI
                     VTHEKSTLEANVANMAKEYLTKIQTYNKMPYNAMKLNQSEIEVDYSYSLLKETNKDLV
                     LSVVKKAEKQEALVVRFYNSKEETKSANIVFNKNIKIAKWINLNEKELESISIDNNSV
                     NVECLMNQVKTILVK"
     gene            103713..104855
                     /locus_tag="KRH23_000257"
     CDS             103713..104855
                     /locus_tag="KRH23_000257"
                     /EC_number="2.7.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008887 - glycerate kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HHS5223556.1"
                     /translation="MKILISIDSLKGSLSSIEAGNAIKKGILKVKEDAQVKILPLADG
                     GEGTVDALVQGMNGKKETIEVTGPIAKKVDATYGLLKNTSTAIIEIAQASGLTLVPTE
                     LRNPLYTTTYGVGEIIKEAINKGYRNFIVGIGGSATNDAGIGMLQALGFEFYDENNKL
                     VGLGGKVLNEIRHIKIENRLKELDECKFKIACDVNNPLFGKNGAAYIYGSQKGATSEI
                     IEELDNGLRNFSKVVKNYLSKDVANVEGAGAAGGLGFAFLAFLNSKLESGIKIILEEI
                     KLEEELKDADFVITGEGRLDNQTAMGKAPIGVAKLAKKYGVKVIGLAGATTEDAVKCN
                     EEGIDAYFSIVNRAMTIEEAMDKATASENMTSTTTQIFNLITSIQQ"
     gene            complement(104990..106903)
                     /locus_tag="KRH23_000258"
     CDS             complement(104990..106903)
                     /locus_tag="KRH23_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HHS5223557.1"
                     /translation="MKTSKKELFLNFIKTQHDWIDSSTLANYLNVSTRSIRKYVNEIN
                     SNGEFILSSKKGYKVNLNNNCQTKVDSSENISPDNRLNLILKELIVNSNGINIFDLSE
                     ELFVSPATIEGDIVKANKFIGSYNLKIKQSKFLLKLIGNESAKRKLMSSIIFKETGSD
                     FLSLFDVQKIYQEYNLTKLKENIIYILKKYNLFINEYAINNILLHLMITIDRIKKNNY
                     IDSVEVVNYIDNNVDINIAKDISNFLESEYNITLTSAELYYLVFQLTNKTTVLNYNQM
                     DTKSLSNYIDEHFVKLTKKIIKNVYDLYLIDLSDEEFVVKFTLHVKNLISRAKNNQVL
                     RNQIPQKLKDSYPLIYDISVYICNQIQTLESVDIDEDEISYISLHVGSFFDRQKLLED
                     KVLCALITPNYYDLQFKIVRDLEKRFNESIEIIQIFSDTHNLDFDNKVDMVITTLPIN
                     NRCPIPFVYVNPYLNRKDYDNIQSKFIQIKDRKNILTVQNHLEMYFSESLFMKNIYLD
                     SAKDYIKFMGNILYENKYVKPNYIDDVLIREKMSSTAFNNNVAIPHSMKMDALKTGVC
                     LIVNDKSVKWGEEKVQIIAMIPINEKEKEKFNYIFESFIEILSEWNNVKELTKADNYS
                     SFMNRIAYLIQNI"
     gene            107151..107468
                     /locus_tag="KRH23_000259"
     CDS             107151..107468
                     /locus_tag="KRH23_000259"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HHS5223558.1"
                     /translation="MKNIKVLLACGSGASTGFMATSMRKSAKKKGIEADIKARSESEI
                     DKYLPEIDCLLLGPHLDYMKDEIQKKADEYNVPVACISKTAYGRLDGVKALEEALELI
                     LNK"
     gene            107491..108723
                     /locus_tag="KRH23_000260"
     CDS             107491..108723
                     /locus_tag="KRH23_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HHS5223559.1"
                     /translation="MNKFIDLLSEKFTPVVNKITKNIWVQSVQSTIMKVLPMVFVGSL
                     VTIVSVLKNYISFLPDLSPINQYTFGLLGLFIAFLLPMEIMKNKKFESMSVVAGLAGA
                     GLMLMMIRPEITNEGAIFNFNRFGGEGMLVALVAGLFSGLIMSLFGSFSFFGEDSALP
                     DFVSKWFDSMLPIAVIMFIGWGLIYGLNFDMFEIIVRIFKPVSDIAQTLPGFVLLNFL
                     VVFLYSLGISGWVLSPITYAIQLSAIAANAAAVASGGLATNIYTYEVVQTGWITLGGW
                     GATLPLVLMMCLSRAGRIKAIGRACIVPSIMNINEPVMFGAPVAWNPFLMLPMWIGTV
                     VISITTYLSMSMGFVTIPSKVFNLWYVPFGISTFMVNQDVRGLIVLAINIVLLFMIWY
                     PFFKAYEKEELKLESQEV"
     gene            108752..109105
                     /locus_tag="KRH23_000261"
     CDS             108752..109105
                     /locus_tag="KRH23_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HHS5223560.1"
                     /translation="MTIEEHIIDEELVEVAMQIILRAGEARTEIKHALNDLEKFDYRN
                     ADLKLAKAKGFMTEAHRAQTKIIQGEAGGEKRAHSLLFAHAQDTLMTIFSELNITMSL
                     VGIVKSIEYKVNNSK"
     gene            109136..110572
                     /locus_tag="KRH23_000262"
     CDS             109136..110572
                     /locus_tag="KRH23_000262"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HHS5223561.1"
                     /translation="MSKFPKGFLWGGAVAANQLEGAWNEGSKGWCLADVHMYDKDRDI
                     SKPYESDMTIERIKFAMKDNNGYYPKRSGIDFYHTYKEDLKLLKELGLKCFRFSINWA
                     RIFPNGDDLEPNEEGLKFYDNLINEVIDNGMEPIVTLLHYETPLNLVLKYKGWSNRKV
                     VDFFVRYAELILNRYKDKVKYWIVINQINLMYHESFNSVAFCVDQVDDVEEAKYQAIH
                     HQFMATALTKKLGKEINSDMMIGMMMADCTSYPEDCDPENVVFALKRNRIQYFFTDVS
                     FRGEYPVYIKRFFKENNINIVIEEGDDKILKENTMDFLALSYYYSTTVSASKNTMNPT
                     DNIKNPYLKANPWGWAIDPKGLYNTLSQYYDRYQKPIMIAENGFGMHDKFEDGKVHDN
                     YRIDYLGKHIEQIGEAIADGTEILAYCMWSPIDIVSCSSQEMEKRYGFIYVDIDNNGN
                     GSKKRYKKDSFYWYQNVIRTNGEELKEK"
     gene            110671..111288
                     /locus_tag="KRH23_000263"
     CDS             110671..111288
                     /locus_tag="KRH23_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YczE/YyaS/YitT family protein"
                     /protein_id="HHS5223562.1"
                     /translation="MNVIKKFIFVILIINILGCGISLILQSSLGSDAITLLNEGIHIK
                     LGISYTIAGLIYNGTLLLIALLLNKKSLGLGSCVYVLVAGIFIDLYIYLLLDFNISSL
                     GIIIRIMSFIIGHILMCSGFAMLIKFDIGMSPLDAILIYIEGKFKYPYKVLKTIADVI
                     FLILGVYLGGNLGFGTIFSILCTGTTISIVSKMISVNKKRYYSNI"
     gene            111584..112336
                     /locus_tag="KRH23_000264"
     CDS             111584..112336
                     /locus_tag="KRH23_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HHS5223563.1"
                     /translation="MIIELNKSNSENLTKTELEIIKFINENESILPELSIVEIAHETY
                     SSPATVSRAIRKCGLNGFNELRYRLTVKDENDDIQNMGDIINKSFIEAQRVIEQISLT
                     TLINIIKTINKSSKIYILARGLTEYVAKEFSLKLQLLDFNVVFINDPNIMKIKSKSIK
                     KDELIIIFSLNGNTIELVESAQNANLVGAKVITCCCSESAKLIKYSDLYIVGYKHEHI
                     SISEYEVSSRLPLYIISRIIIDYMVRYNNSEN"
     gene            112438..113358
                     /locus_tag="KRH23_000265"
     CDS             112438..113358
                     /locus_tag="KRH23_000265"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008443 - phosphofructokinase activity
                     [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase family hexose kinase"
                     /protein_id="HHS5223564.1"
                     /translation="MIYTLTTNPAIDMNISTNGIKRKLVNRTSNAVYSPNGKGLNVTF
                     VLGHYGIESKILGFFGGFSGKYIVEESEKRGFDVLPTWVEDTTRINIFLNDGSDEFKF
                     VNSGSYVNEKQKLDMLDKIQSLEDISYLSISGSLPPGIDDNYYEDIFKICENKSIKTI
                     LDISSPKLKELLQYNPYLIKPNDEEIKDIFGIIVRDEEDIKDVLKLLHLKGAQNILLT
                     LGEKGSYFYNGKSIYYASAQPVTVVSSACAGDSALAAFLSIWLENPEHIEEALKRSAA
                     TGASVAESNGIGNLENVEDYIKNIRVRKVV"
     gene            113361..115277
                     /locus_tag="KRH23_000266"
     CDS             113361..115277
                     /locus_tag="KRH23_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022877 -
                     protein-N(PI)-phosphohistidine-fructose phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-specific PTS transporter subunit EIIC"
                     /protein_id="HHS5223565.1"
                     /translation="MGKKMILGVTGCPTGIAHTFMAEEALKNSARELGCDIKVETNGA
                     IGVENKLTAKDIEMADAIIVACDKNVDMDRFNGKPVIEVPVKEGIHKANELIQRCIDG
                     KVAIRKGNLSSSKIAEEGNLSFGQKLYKDLMNGVSHMLPLVVAGGVLTAISFLWGIYS
                     FDPNSEQYNQIAATLKSVGGYSMNLMVPVLAAFIAQSISGRAGMLAGLVGGMISFDTG
                     SGFLGGIISGFLAGYLVKLFVHLLRKLPRQLEGLKSIFIIPIVSVGLVGVAMLLLGGP
                     CSALNNAMMNFLSGLQNSSPIILGIVIGCMSAFDMGGPVNKAAYVTGTMLLGQGNYLF
                     MAGVSAACITPPLVIAIASTLFKNRFTEEDRAAGLINYILGSTHITEGAIPFAAKNPL
                     KVLPVLMIASSISSILTYIMKIEVPAPHGGFLVLGLVNKPLLWVGCIFVGSLVGAVLY
                     MMVTPKVVNEKNTIENTNATKDEHKNESAESENVSNNISLYSEETVILDVKGKNKTDV
                     IDEMIGILDKSGVLLDKKKFKEEILKREEISSTGFGMGIAIPHAKTDAVKVPRVAVGV
                     SKEGFDFESEDGSLAHIIFMIAATDNGDNLHLKTLSQLSSKLMNEEFLNELLNSKTSR
                     EIVSKLNNEEIKSV"
     gene            115297..116166
                     /gene="gatY"
                     /locus_tag="KRH23_000267"
     CDS             115297..116166
                     /gene="gatY"
                     /locus_tag="KRH23_000267"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase subunit GatY"
                     /protein_id="HHS5223566.1"
                     /translation="MALVTTKQILLDAQEGHYAVGAFNVENMEMVMAVIEAAEELKSP
                     VILQTTPSTIKYAGLDYYLANVKVASEKASVPVAMHLDHGSSFGLAMQALRVGYTSIM
                     IDGSHESYEDNISISKSVVDACMPSDIPVEAELGKVGGKEDDLDGGDGGAYTDPLEAK
                     EFVERTGVSSLAVAIGTAHGLYKGEPKLDLDRLSEIRDVVSVPLVLHGGSGIPDEVIK
                     ESIKRGICKVNYATELRIAYSNGVKDVLNSDPEVIDPKKYGKKGLESVKDFVKSRMEV
                     CGCVGKAIEIVKC"
     gene            116676..118139
                     /locus_tag="KRH23_000268"
     CDS             116676..118139
                     /locus_tag="KRH23_000268"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0009307 - DNA restriction-modification
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HHS5223567.1"
                     /translation="MITGELRSKVDKIWETFWTGGLTNPLEVIEQFTYLLFIKGLDEV
                     ETKNEAEATLLGVSFERIFDDGHQHLRWSKFSNEGNSEKMYEIVQNEVFPFIKKLHGN
                     KDSAYAKYMGDAIFKIPTPLMLSKIVDGISNLELSKDRDTKGDLYEYLLSKVATAGTN
                     GQFRTPRHIIDMIVRLIKPTPEDIIVDPAAGSAGFLVSSQQYLRDNHSSLFLVQGLKE
                     HFNNGMFYGFDMDRTMLRIGAMNMMLHGVDNPNIEYKDSLSEVNTDKDKFTLVLANPP
                     FKGSLDYEAVSADLLKVTKTKKTELLFLALFLRVLKIGGRCACIVPDGVLFGSTGGHK
                     SIRKEIVDNHKLEAIISMPSGVFKPYAGVSTAIMIFTKTGTGGTDKVWFYDMKADGYS
                     LDDKRNEIKDSDIEDIIKRFDNLDGEVDRKRTEQSFFVDVEEIRENGYDLSINKYKEV
                     VYEEVIYDAPNVILGRVKELEKEIAVGLEELERMLEV"
     gene            118143..119243
                     /locus_tag="KRH23_000269"
     CDS             118143..119243
                     /locus_tag="KRH23_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HHS5223568.1"
                     /translation="MEYIKLNELCYINIGKTPSRNTSDYWGSGNRWLSISDLKEKYIL
                     KSKEEITDLAVEKANMKLVPKNTVVMSFKLSIGRVAILKEDMFTNEAIANFQIKNNEL
                     ITYEYLYYALRTLNFNNTDRAVMGATLNKSKLNDIKIPYFTICIQNKMVEVLNKAQEL
                     INKRKEQIEALDELVKSRFIEMFGNVITNSKDWDTELLGEISNLKAGKNIKAKDIYEK
                     NSHELYPCYGGNGLRGYVKMYSHKGTFNLIGRQGALCGNVKYVNGKFYATEHAVVVQP
                     KVDINSYWLYFTLKELDLNRLSTGAAQPGLTVGKLNEVEIPKVPVYLQNKFVDFVRQI
                     DKLKSRMEDSLKELENNFNSLMQKAFKGELFN"
     gene            119276..119584
                     /locus_tag="KRH23_000270"
     CDS             119276..119584
                     /locus_tag="KRH23_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5223569.1"
                     /translation="MNQIELDLYHNMVNIYKEANLQCNYKPTRFLQLINNKGALLAAK
                     ELINKEGATEGFTRLWECKRLDLSLEVLVLKEKYKELFTDEEREICINRLKDYGYKFN
                     "
     gene            119617..119997
                     /locus_tag="KRH23_000271"
     CDS             119617..119997
                     /locus_tag="KRH23_000271"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HHS5223570.1"
                     /translation="MRNIPNEIKNSIINVFPKENTLAIIIFGSYGTDKHTSESDIDIA
                     WIPIKKVPITELATKTEALRNILDIDVDLKIVTDNYTIALKKAILEGEVIYESKDFKD
                     YINKFYFENSDVIDILDWRDMYGN"
     gene            119987..120415
                     /locus_tag="KRH23_000272"
     CDS             119987..120415
                     /locus_tag="KRH23_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5223571.1"
                     /translation="MVIRNKLSWNSIEEVNRDFGSCLYDLQNFKILYDKEEMPELWAR
                     YIKEGFKSYMVSFLELTKAMLYYKSIDLNIKSKNFYDYLLACEYHNLLPKNSSIVIET
                     LRKLRNDDSHGYDIPQFEDMYELFTENEEVFVSIRNSCKK"
     gene            120465..123800
                     /locus_tag="KRH23_000273"
     CDS             120465..123800
                     /locus_tag="KRH23_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HHS5223572.1"
                     /translation="MGNFDFLQKKKNFNSFNTACLEAEKSILVSPSTCATITRRALEL
                     AVKWLYANDSDLVLPYQDNLSTLIHNNSFIELIDYDMLPLLKYIVKLGNLSVHTSANI
                     ERGEAILSLNNLHQFVSWIDYCYSDEYTAEDFNEDLLLHGEEKRTRPDELKNLYERLS
                     SKDKKLEEVIKENEELRKSLTEKRKVNTVNYDFKIDEVSEFETRKRYINIELKLAGWE
                     FGKDIWEEIEVQGMPNESGVGYVDYVLYGENGKPLAVVEAKRTSKDPKIGQQQAKLYA
                     DCLEKRYSQRPVIFLTNGFDMYIWDDYSDRKVYGFYKKSELQLMIDRRKSKKSLSSVT
                     INDEISNRYYQKEAIRAVCEALENKQRKTLLVCATGTGKTRIAISIVDVLSRHNWIKN
                     ILFLADRKALVKQAKKSFTKLLPNLALCNLLDSKDSPEDARMIFSTYPTMMNAIDDTK
                     SKDGKRLFTPGHFDLIIIDESHRSIYKKYKSIFDYFDSYLMGLTATPKDEIDKNTYSV
                     FDMENGVPTYAYEYNKAVEDGYLVDYTSIEFKTKIMEDGIKYDELSDEEKEEYENTFN
                     DDESIGDEIGNNAVNEWLFNSDTIDLVLNKLMTEGLKIEGEEKIGKTIIFAKNTKHAR
                     AIVERFNKLYPKYGGNFVKAVDYSINYVDSIIDDFSDKNKLPQIAVSVDMLDTGIDIP
                     EILNLVFFKKVRSKTKFWQMIGRGTRLCPDLLGVDMDKERFLIFDFCNNFEFFKFNPK
                     GFEGNKAETLTEKLFNIKVSMVKELQDIKYIEGEYAELRKELLEELITSVKALNEDSY
                     IVRMNLSYVHKYKNENVWSNIGAVAQNEIREYISPLITSYGDDELAKRFDVVMYNIQL
                     AYLQNNNASKGIRHVMATAEKLSKLGTIPQIQQQKYTIEKAMTEDFWEDSDIFEVEEV
                     RISLRELIKYLEKSSQKIYYTSFEDMIVAEDRNDSVYNANNLKNYKKKVEYYLNIHKD
                     ELAIFKLRNNKKITKQDVETLEEILLKQLGNCDDYKKEFGDTPVSQLVRRLVGLDREA
                     ANEAFSEFLNNKSFNTKQIHFVKLIVDYVVKNGFIEDNKVLMEDPFRTVGSIIDLFEN
                     HIEERNKLIKTINKIKENASEIG"
     gene            124181..126244
                     /locus_tag="KRH23_000274"
     CDS             124181..126244
                     /locus_tag="KRH23_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF262 domain-containing protein"
                     /protein_id="HHS5223573.1"
                     /translation="MKAGEIEFLSYLEGSNKSFVVPVYQRNYNWKKEQCKRLFDDLED
                     IIDSGFRTHFLGSVVSIYSMGKEYLIIDGQQRVTTVSILLIAMCQIIKEFGESKGIIT
                     TEEQIKECYLINKHSRDKDGKIKLKPIAEDRKAYYELFEEEMNTDRNSNIVSNYLYFY
                     NRIKEDNISIDDLFDAIQKLTIVEIELKNGEDDPQLIFESLNSTGLDLSEADRVRNFV
                     LMGRSSKLQEEFYNNYWYKIEKDTSSNVSSFIRDYLTIKERSIPNKNKVYFSFKRYVS
                     DNGIDIEILLKDLLKFSNYYREISYSCTDDNDVNKVLKRINKLEIFVSYPFILELFDD
                     YNEGIINKKVLVESLNLVECFILRRIVCDVPPNALNKVFMNLGREIKKFSDYKENYSN
                     ILRYIFINKKSSQRFPTDSEFSNAFETKDIYNTKSKNKLYILERLENYNNKEIVDLEN
                     LINNNMLNIEHIMPQTLTNKWKESLGDNYKEIHDKYLHTIGNLTLTGYNSKLSNKTFE
                     EKKEMEDGFKDSRLYLNKYISSIDKWNEEEIKNRTKILLDRAVEIWKYPSVTYEPPSN
                     SENIFTLEDDDVNFTNESIVSFSILGESYKAKNWTEFYEQVALTLYDLDSVRFNSIVD
                     KTYKRDFIDNIKSRDAYKLRKGIKISENIYLETNLNTEAKLNIIRFLLNEFDIELNEV
                     IFSIK"
     gene            complement(126461..127027)
                     /locus_tag="KRH23_000275"
     CDS             complement(126461..127027)
                     /locus_tag="KRH23_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CD3073 family putative ECF transporter S
                     component"
                     /protein_id="HHS5223574.1"
                     /translation="MDTKKVTFSSMCIVINIVLGMVISMINIPLLFLDTIGTVLGAVV
                     LGPFWGALIGGCTNLVLGVISGPTNIPFALVNIVLGLIVGYISKKKGFGYKEAIITGV
                     ILSIVCPLIGTPISVLLFGGLSGSGADLLVGFLVQSGQKIFTAAFFPRILSNIVDKPL
                     SCIMVVYFISKMPKGFIKQYSKNTSSSY"
     gene            127193..127714
                     /locus_tag="KRH23_000276"
     CDS             127193..127714
                     /locus_tag="KRH23_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CD3072 family TudS-related putative desulfidase"
                     /protein_id="HHS5223575.1"
                     /translation="MKRNREIVVVCHCILNCNSKVEGLSEFKGAQNIAIDLINKGYGI
                     IQLPCPEMIMYGINRWGHVKEQFDNLFFREQCRQMLIPHVRQFDEYLKNDYDIKSIIA
                     IDGSPSCGYNKTCSSKRWFGELSGCNELMDKINDIQMVDGKGIFIEELEKLLKEYNLN
                     IPIVGFDELREDK"
     gene            128514..130592
                     /locus_tag="KRH23_000277"
     CDS             128514..130592
                     /locus_tag="KRH23_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HHS5223576.1"
                     /translation="MIKISEDYIEKRFDNELLRIEAWGKNSLRIRSFVDQNFVDENYA
                     LNEKPKLNKDDITINKNEDGSAIIKNGKIKAVLDHRDRITFYNDKNEILLKEYIRLRA
                     VKHDDGGEDVGTIEITKDFNSTLKLKSREYRPSYSGEFEVTTRFESEPSEKIFGMGQY
                     QHKFLDLKNTVLELAQRNSQISVPFYISSLGYGLLWNNPGIGKVSFAKNMTEWKMFST
                     NFIDYWITCGESPKELNKNYSQVTGTVPMMPENLLGLWQSKLRYRTSEEVLDVVKEYS
                     KRGIKLSSIAIDYFHWPKQGEYKFDLDYWKNPKELVKKLKEEYSVEPIVSVWPTVQSD
                     AENYNDYLENGYLVNVNRGVRMTMQIQGNTVFVDMTNENAREYVWDRIDKNYKQLGID
                     YYWLDVAEPGYSVYDFDNYRYKKGNVLSCGNIYPIDYLKMIYDGLHNDIESVVTLVRG
                     AWAGAQKYGALVWSGDIDSSFEAFNNQVNTGLNMGLAGIPWWTTDIGGFHGGNPKDPE
                     FRELMVRWFQYATFSPILRMHGDRLPHSKPLSNKGGGSMVTGAPNEIWSYGEEVEVIL
                     TKFIKIRESLKTYLKKLMKEAHEDGTPVMRTLFYEFPEDDKTWEVDNTYMLGDEILVA
                     PIMNYKDRSRKVYLPKGHTWENIFSGVSYEGGKTYEVECPLEEIPIFLKQDSSYNFKE
                     LKNILGEVKS"
     gene            130592..131371
                     /locus_tag="KRH23_000278"
     CDS             130592..131371
                     /locus_tag="KRH23_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HHS5223577.1"
                     /translation="MEPQLWQLLLIVLYGFFINYEKNSTMFGTYQPVTAGFITGLILG
                     DINTGLYIGGTLQLLSLGISNFGGASIPDYQTASIVATFITITTKQEASVGISIGIPV
                     ALLMVQLDVLRNTIGIWLVHKAEDGAKKGNYKNITYMQMLGVLLTAATTGIPVALSVI
                     FGPSLINTILKYTPEWLTGGLTVAGGLLPAVGIGLLLRYLPAKEYFSYLVIGFVLAVY
                     MKVPLLGVALIGGAIALIIYKKNLENQEQQYTVVGGMDEDE"
     gene            131364..132173
                     /locus_tag="KRH23_000279"
     CDS             131364..132173
                     /locus_tag="KRH23_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HHS5223578.1"
                     /translation="MSDKVSLNKSNEKVKKSVLWRWFFTSSVSSNYEKMQALAYCYAV
                     LPFLKVVYKDNPEKLQSAVLNHLQFFNTNPWVAPYILGINVAMEELSSEETEEAVASI
                     KTGLMGPVAGLGDSLFVVIPWTIFGAIAANMAIDGSPFGILLWIVVSVALKLLSIPLF
                     NAGYTSGTKLISSIEKSLKILTESTSILGLMVVGALIPSVVKANVALNFQQGDFTMKG
                     QEILDQIMPGLVPAILVVIVYWALKKNIKPIYLILGVMVVSIILYALGILK"
     gene            132193..132675
                     /locus_tag="KRH23_000280"
     CDS             132193..132675
                     /locus_tag="KRH23_000280"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HHS5223579.1"
                     /translation="MEMKGIKNIRIDDRLIHGQVATMWSNKLGVTRLMVVNDAVANNS
                     VQKQVLRMATPAGIASSIITEETAIKNITAGKYEGQNVLLIVKSPVDLIPFVEAGFKI
                     HNINVGNMSSRKDTTVLRPNISVTEEEKEAFKRLLDEGIEITTIMTPDDKKTYLVDIL
                     "
     gene            132696..133100
                     /locus_tag="KRH23_000281"
     CDS             132696..133100
                     /locus_tag="KRH23_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HHS5223580.1"
                     /translation="MNSIILMSHGNMAEEVLNSAKMIIGDSIDYPTVNMKQDDGIEGT
                     IEKLKKALEVYKESSEIIIMADLLGGTPCNAALLVANNDSRIKIISGLNLGMVIESAF
                     LDTKELAAKLEKIGKDNISMVEQNASLLSDDE"
     gene            complement(133256..134416)
                     /locus_tag="KRH23_000282"
     CDS             complement(133256..134416)
                     /locus_tag="KRH23_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HHS5223581.1"
                     /translation="MVTDKYTIREMNERLVLEQIIKNGPISRASIASTIGLNKATISA
                     ITKKLIDESLVHEIGIGNSTHSGGRKPILLVFNKCAGISLSMDIGYDYIFSSLSYLDG
                     TIINSKKLTDIQVSKDNVIQLIDEIINSYNISKIDTPYKVIGLTLAIHGITCENKVLF
                     TPYYNLNEIDLYSILSKKYDFPIHIENEANLTALAENTFSTVHNSLLSLSIHSGFGSG
                     IIINNKLYSGRNGMSGEIGHTIIMPNGKLCPCGNRGCLEQYCSEKKVFEQLSSLENIP
                     KIDSDIVKQLYYEDNQNAKKVIHEFCSYLTIAINNAITTYAPEIIYLNSQIISDIPEI
                     LQITKDMLVSSFNKGINIEISSLGSEASLYGGSAVNIKSFLNIQNLTLINEI"
     gene            134624..136174
                     /gene="xylB"
                     /locus_tag="KRH23_000283"
     CDS             134624..136174
                     /gene="xylB"
                     /locus_tag="KRH23_000283"
                     /EC_number="2.7.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004856 - D-xylulokinase activity
                     [Evidence IEA];
                     GO_process: GO:0005997 - xylulose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="xylulokinase"
                     /protein_id="HHS5223582.1"
                     /translation="MKLEYVLGVDIGTSGTKTVLFDKLGNTIKSCTYEYPLIQEKSGW
                     AEQDANDWWKAVVESIREVVQSLNISSECIKGIGLSGQMHGLVMLDNEGKTLRNSIIW
                     CDQRTVKECEEITDLVGEERLIEITANPALTGFTASKILWVRNNEPDIYKNTNKILLP
                     KDYIRYKLTGEYATEVSDASGMQLLDIRKRDWSDEVLEKLNIDKNLLGKVYESQEITG
                     YVTRDVASLTGLKEGTIVVGGAGDQAAGAIGNGIVKDGVVSSTIGTSGVVFAYTKEPK
                     IDKEGRVHTFCHAIPNTWHVMGVTQGAGLSLKWFKDNFCQSEVEVSNSLGEDVYEIIN
                     NQVSQVPTGCNGLLYLPYMMGERTPHLDPYARGVFFGLSPIHSKKEIARSIMEGVSYS
                     LKDCMDIIENLNIDVNEVRASGGGGKSKVWRQMQADMFNQDVYTINSSEGPALGVAIL
                     ALVGAGIYENIQKACDAIIKTSTKLEPISENVDTYNIYHRLYKRIYKSLKDDFKLLDE
                     VVNAKINN"
     gene            136270..137607
                     /gene="xylA"
                     /locus_tag="KRH23_000284"
     CDS             136270..137607
                     /gene="xylA"
                     /locus_tag="KRH23_000284"
                     /EC_number="5.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009045 - xylose isomerase activity
                     [Evidence IEA];
                     GO_process: GO:0042732 - D-xylose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="xylose isomerase"
                     /protein_id="HHS5223583.1"
                     /translation="MSEIFKGIGQIKFEGVKSDNELAFRYYNPEQVVGNKTMKEHLRF
                     AMSYWHTLCGEGNDPFGVGTVERPWNNITDPIEIAKIKVDAGFEFMSKMGIEYFCFHD
                     RDIAPEGRDLEETNKILDEIVEYIKVNMEKTGIKLLWGTANMFGNPRFVHGASTTCNA
                     DVYAYAAAQVKKAMEITKYLGGENFVFWGGREGYETLLNTNTELEMDNFARFLQMAVD
                     YAKEIGFTGQFLIEPKPKEPTKHQYDFDTATVLGFLRKYNLDKYFKMNIEANHATLAG
                     HTFQHELNIARINNVLGSIDANQGDLLLGWDTDQFPTNIYDATLAMYEVLKQGGIAPG
                     GFNFDSKVRRASFEVEDLFLAYIAGMDTFAKGLLIAHKLLEDEVFENFTKERYASFSE
                     GIGKDIVEGKVGFKELESYALQMPVIKNKSGRQEMLEAILNRYIYEVDTISNK"
     gene            138129..139328
                     /locus_tag="KRH23_000285"
     CDS             138129..139328
                     /locus_tag="KRH23_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S41 family peptidase"
                     /protein_id="HHS5223584.1"
                     /translation="MKKKVLFLVIILAFIILLGNSTYSQKNQLSEEEKVDDFNYVYNV
                     VKTGYPYLGVNKRLNNIDWLANKDEYTKRIKNTENDEEFIEELSSILSDLNNKHTEVI
                     DNKKRYELFKKSYSNNDWYDFLNDKKVVDRYDSMNLKIKMPDDIFVKKELILKDVIKG
                     QIGYMYLPSMSSKNGSINNDLKIIGDYINTLEKHKALIIDIRGNLGGSDSYWQGIVSK
                     LIKNDVKINGYRIYRNNNEIVKKYTNARNIKLNPVENLPASVKENAPKEIIKDFNDFE
                     DTSYTIKSTDDSKFKGNIYLLVDRKIYSSSESFAMFCKENKFATLVGETTGGDGGCID
                     PVLFNLKNSGLIVRMASCMYLNKNGICDEEFKTIPEFKVKDCKRTADFKDDNCIRKAL
                     ELENINY"
     gene            139495..140280
                     /locus_tag="KRH23_000286"
     CDS             139495..140280
                     /locus_tag="KRH23_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HHS5223585.1"
                     /translation="MRLEEMIFLNYNKLNDTDLLIWKYITANKKHCSKMSINELAMKC
                     NVSRATITRFVKKLDLKGFSEFKVLLSWESEKVHVIENQSFDIACNSIIKYVEDQKNK
                     DYDALCKLLYESRTIYAYGSGDIQNVVAKQIKRMFLSCQEIIYDFEGRTFDDSFYNIV
                     SKNDVMIIISLSGENENTLNIARRLKLIGTKIISITEFKNNTLTDLSDESIYISATNI
                     SFLQMHPSYKLTMLYFILIELLFIKYSIYKRHRMITEGIDCKL"
     gene            140450..142015
                     /locus_tag="KRH23_000287"
     CDS             140450..142015
                     /locus_tag="KRH23_000287"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015144 - carbohydrate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucoside-specific PTS transporter subunit
                     IIBC"
                     /protein_id="HHS5223586.1"
                     /translation="MMKKIQRFGGAMFTPTLLFAFAGIMVGFSIVFQNQSIMGSLATP
                     ENIWYQFWGVISSGAWMVFNQLPLLFAISLPIALAKKQQARACMEALATYLTFNYFVG
                     SMLSFWGKSFGVDFAAEISAGSGLVSIAGIKTLDTGMVGALLISGIVIYIHNRFYDKE
                     LPDFIGLFRGSSLVVAICFFVMIPVALLTCFIWPHIQNVIRHLQTFFINSGNIGVWCY
                     AFLQKILIPTGLHHFVYAPICYDSVVVPGGTSVYWATHIQDFQTSAKTLKEMYPIGFS
                     LSGLSKVFGSLGVFGAFYVTAKPEKKKKVLGLMIPATLTAVLTGITEPLEFTFLFVAP
                     LLFLVHAFLDACLQTISFALGVVGDFGGGIINWVVLNWLPLGMYHWKVYVVQVVVGII
                     FSFIWFFVFTFLIKKFDMKTPGREEDSEETKLYTKNEYLETKDEKGNKLSKASQQASE
                     YIKLVGGAENVVDVTNCATRLRLTLKDDSIISKEEDFKAVGAHGLVHNGKAIQIIIGL
                     SVPSVREEFENLL"
     gene            142029..143360
                     /locus_tag="KRH23_000288"
     CDS             142029..143360
                     /locus_tag="KRH23_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-alpha-glucosidase"
                     /protein_id="HHS5223587.1"
                     /translation="MERKRQRILIAGGGSTYTAGIVTMLIESVAKFPIESIKLYDNND
                     ERQRKVAEACAIIVREKNPEIKFSYTTNPEEAFTDIDFVMAQIRVGLYALREQDEKIP
                     LKYGVVGQETCGAGGIAYGLRTIGPIIEMIDYMEKYSPNAWMLNYSNPAAIVAEACRV
                     LRPNSRIINICDMPVCLEEIFARVLGLNSRKDFDVRYYGLNHFGWWTSIKDKEGNDLM
                     PELQEYCAKKGYEEFTPQGQHKESSWLETMRAAKDLLEIEPTTLPNTYLKYYLMADET
                     VEHANPNYTRANEIMDRREKDTFEECERIIKNGTARDTWFDASEHSQFIVELACALAF
                     NTQERFLLIVPNNGAIENFADDAMVEIPCLVGKDMVEPMSIGKIPTFQKGLMEQQVAS
                     EKLAVEAWIEKSYQKLWQSFTMSKTVPSAKVAKEILDEMIVANKDFWPTFK"
     gene            143374..143862
                     /locus_tag="KRH23_000289"
     CDS             143374..143862
                     /locus_tag="KRH23_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5223588.1"
                     /translation="MITNKIKNITAVLKDENIFLSVVMVCFLILPVLYIVYLELTSLF
                     TNISFSQLLNNDVNASLNLISNFSAVYSAYVIYNIKKNKEIKENMIAFYLVLLGQIFQ
                     IYTITIVIMFTYIYKFVGIKQIISSIKELQWGKSYKALFSSIAVCLISLFVMIIRIKL
                     IM"
     gene            143876..144343
                     /locus_tag="KRH23_000290"
     CDS             143876..144343
                     /locus_tag="KRH23_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HHS5223589.1"
                     /translation="MFFKRKKEAITINSYIDGKIINLGEIPDKVFSTKVMGDGFAMIA
                     KDNILKSPTKGVISFIAQTNHAIGIKLQNDVQILIHIGLDSATTKKENFKLEVKQGQE
                     VNMGEKLVEIDNKLLENTLYIPLVIVENPNTVKYHLSNLNQEGNSGIKVINFD"
     gene            144346..145497
                     /locus_tag="KRH23_000291"
     CDS             144346..145497
                     /locus_tag="KRH23_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HHS5223590.1"
                     /translation="MINKAIKFKFIIFYFFSYIIFAFASTKFTPFLSKLGYSAFERGI
                     ILSSYAITNILFQLLFGVLADKYQTMKKIVLISLSVYGIASVIMFSTESATFIIYLLL
                     VALSGGLLNTCCSLYDTWIIGCGDNINNYLSFIKTFGSIGWAIGSMVASYLILRFSYF
                     GLSVAIGLIVVLLIINILLLPDIEKINKKINVTNKDIIELLKDKKYILLVCILFLLYS
                     MVVANNCTVIDKMIALNATNSQISLKWSLQSLLEIPTYLAGSYLLKKYSSLNLLKLSA
                     IMITVQFLLFALTNDSNIIIILCVFQVFSTPLILITSKRLIFEVSPKKLRSSSQLIAL
                     SIFMGGSSLIIPTVAGFLSINIGYNYTLMVLSLFGCLAYCLIVLLNYLQ"
     gene            145815..146567
                     /locus_tag="KRH23_000292"
     CDS             145815..146567
                     /locus_tag="KRH23_000292"
                     /EC_number="7.6.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHS5223591.1"
                     /translation="MKEILKIKNISKDYGIKGFKTNVLKNISLTVNEGDFIAIMGPSG
                     AGKTTLLNLMSTLDKQTSGEIILDGINISKVKNNELSKLRREKIGFIFQDYNLLDNMK
                     LMDNIALPLALGKKKSKEIEAKVFSIAKKFGLENHLDKYPYQLSGGQKQRGAAARSLI
                     TNPTVIFADEPTGALDSKSAYELLESLEKINRENNATIIMITHDPLTASYSNEVYMIN
                     DGNIKCKLNKGNSRKEFYGKIMDMLASMGGEM"
     gene            146568..148475
                     /locus_tag="KRH23_000293"
     CDS             146568..148475
                     /locus_tag="KRH23_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HHS5223592.1"
                     /translation="MSILGIAYNNFKSNIRTYLAFFISMVFSVVVLTNFELLRYGDAI
                     NVLQEENKKFTLSVLVAVIMILSVFLFFFIWYATNIFFKNRSKEIGILSFMGLDLYTI
                     GKIYFVENMLIGISSCITGIIIGIITSRFFQVVIIKLSGFNIKVSNGLSIEAILYATL
                     IFISIFIIMAVKGFITICRSSVINLINISKKQEKIPKVGIGIYILAIVSIIVIGYGYY
                     LSTNIRTGDITSVLPVIGIIIAGTYGLFKSVMPVIFDIIIKNKKILFNGNNIIAINNI
                     NYRLNKNYKTYAIIAIIITTTISTLGASVAMKHIHKNAQEQRNVYTISIVSMDKDEVN
                     KKQIENIIKDTNKIKYSVNPELTILKKTDIKEAYDTTDTIMKYSDFCNTLKVNGNDKE
                     LKEYGERLVSGNNVIELKSPQTIASIATKEAKIKLDGQLYNISRGEVKVPVLGTGLNQ
                     SIIVVNDDTYFKLRDKGQQVYFYGAKVFQEENSQVMFNNIEKNLSLKNGYIQNGYKAQ
                     GESQWMKFAYVVLVFLFLVFAIVAGSIIYMKIYSDAYEDKEKYKILLKIGTTEKDINR
                     AILKEVAIFYTLPMLSATISSYFALRLAGDLLMTDLFDIYILSLVICLIIFVIYGAVS
                     VNKFKSVVYKN"
     gene            148627..149307
                     /locus_tag="KRH23_000294"
     CDS             148627..149307
                     /locus_tag="KRH23_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HHS5223593.1"
                     /translation="MYRILLVEDDIDLSKEIALALEKWGFKVELIDDFEVVLDEFIDK
                     KPDVVLLDVNLPLYNGFYWCEKIRAISNVPLIFLSSRDSDMDLIMGINNGADDYITKP
                     FSIEILVTKINGIIRRVYNYSDSNSILYCEDLMFDVGKGIIKHKYKDKSIELTKNEIK
                     ILTLLLKNKNRVVSRESLMMTLWDNDEFVTDNALTVNMNRLRSKVKELGFDDFIKTKK
                     GIGYIIQC"
     gene            149301..150320
                     /locus_tag="KRH23_000295"
     CDS             149301..150320
                     /locus_tag="KRH23_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HHS5223594.1"
                     /translation="MLVKYLKGRSKYIALPLVVVSIINIYLFAIDIFKNKYSELIYLD
                     FLVLFIIMVFFVIDYINFRNSYTNLYNCIENSGEIDSYLVDGQSFEENLIKDIIENLK
                     IKNNSDIETYKQSLKELDEYIAKWVHEIKIPISSLSIITDRLSSIEDSLDIKNQVAKI
                     NFLVNSILYSSRSNTMFEDVFINKFNLEKLVKMSIKNNSFLLIKNNVEVSLNELENDV
                     YTDSKCMSYVLDQIINNAIKYSKEVGKIEFNSKKLENGVVLSIKDFGIGINEEDISRV
                     FDKGFTGKNGRNQLYKSTGMGMYFVKKMIDSLGHEIEVCSKIGSYTIFNIYFYDISDY
                     LSLDS"
     gene            150760..151911
                     /gene="anmK"
                     /locus_tag="KRH23_000296"
     CDS             150760..151911
                     /gene="anmK"
                     /locus_tag="KRH23_000296"
                     /EC_number="2.7.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0006040 - amino sugar metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009254 - peptidoglycan turnover [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anhydro-N-acetylmuramic acid kinase AnmK"
                     /protein_id="HHS5223595.1"
                     /translation="MYSVGLMSGTSLDGVDAVLAEISGNGRNTKVKQIEFITLEIPKD
                     IKDEIRKCCIEEESSVDLICSLNFKLGYLFSKAVKSVCHKANFHIANLDFIASHGQTI
                     FHIPRSYNNFVSSTLQIGEPAVIAYETNTKVISNFRVMDIAAGGEGAPLVPYSEFLLY
                     SDNNKNLALQNIGGIGNITIIPKSCNIDDVFAFDTGPGNMIIDGVCQRLFNRKYDKNG
                     YFASKGKINEEMLKDLMSHKYLSQAPPKSTGREVFGQVYLDNMLNKYKHVDKYDLIAT
                     VTMFTAKAIYYNYKNFILPKVNVDTLLIGGGGAHNLTLIGYIKELLLEVAVLTQDEYG
                     YSSDAKEALAFVILGNETLNNSFSNVISATGAKNKVILGNITPKPFGGK"
     gene            151913..152311
                     /locus_tag="KRH23_000297"
     CDS             151913..152311
                     /locus_tag="KRH23_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5223596.1"
                     /translation="MSNNKKKKRKKNNNYKNAKSTKSNKNTKKQMEKNQRTDYNIPTI
                     SFKSGLILIVSSLVSTVVFPLLLSIFGIDNRFGVVIGNSLITSFAVAYTRYFVETKRG
                     FSLGFFRLYILFALSFAIIGYFWIYKGIHI"
     gene            152573..152881
                     /locus_tag="KRH23_000298"
     CDS             152573..152881
                     /locus_tag="KRH23_000298"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HHS5223597.1"
                     /translation="MRVLFVCSSGMSSAIAVNALQKEGAKNGIDIDVLAVGTQEFEDE
                     VKNGWDIAMVAPQVRHRFDYLKAFADEVSVPCALIQAQAYSPLGGSKLLKQVQELLSK
                     "
     gene            152970..154316
                     /locus_tag="KRH23_000299"
     CDS             152970..154316
                     /locus_tag="KRH23_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HHS5223598.1"
                     /translation="MLDKFTEFLDTKLSTSMARLAEQRHLRAVRDGIVASLPLIIVGS
                     FFLILAFPPLPDSWGVTQYLKENAVTILLPYRMTFFIISVYSTFGIGYSLAKSYKLDG
                     LTGGLLATATLLLTIVPTAIEGLTPDLLKIVEKSPELLAWYNSIPQGWQMPMANLGGG
                     SMFVAIVTSIIGVEIYRFTDKSKFKITMPEAVPASVTRSFEALTPAALIIILMAIVTY
                     FLGFDWHGFIAKLVTPLVSATDTLPSVIILIFLITFFWSFGIHGVSIIGSLARPLWIQ
                     LLDANTASYAAGQAVPGIAAEPFFQWFIWIGGSGATIGLALLLAFRAKSAYGKSLGKA
                     TVIPAIFNINEPIIFGAPIVLNPILIIPFVVAPIVMATVSWFAMSANLVSRVVVTAPW
                     TLPGPVGAYLATGGDWRASVLNLLCIAISIIIYYPFVKMYDKRLLHEEKVEEQEAY"
     gene            154549..155646
                     /locus_tag="KRH23_000300"
     CDS             154549..155646
                     /locus_tag="KRH23_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HHS5223599.1"
                     /translation="MGRLGISIYPEKTTSKEIYDYIDKAAENGFTRIFSCLLSVKDTK
                     ENIIKKFKSINEYAKFKGFEVILDVNPRVFGELEISYKDLNFFKKTKADGIRLDMGFT
                     GSEEALMTFNPQNLKIEINMSNNTNYIDTIMDYQPNKENLIGCHNFYPHRYSGLNLEH
                     FIKCTERFNKYGLRTAVFVTSQNETTFGPWPVTDGLPTIEMHRNIPIDIQVKHIIAMN
                     NINDIIISNCYPTYEELKVLGSMRKDMVTFDVAIEENIREVEKKILFEEIHFNRGDIS
                     DSLIRSTQSRVKYKGYKFELFNTPKIIKRGDIVIESSEYGHYAGELQIALTDMKNSGK
                     SNVVGYIRKEELFILDYIKPWQKFNFKPSTK"
     gene            155745..156659
                     /gene="murQ"
                     /locus_tag="KRH23_000301"
     CDS             155745..156659
                     /gene="murQ"
                     /locus_tag="KRH23_000301"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016835 - carbon-oxygen lyase activity
                     [Evidence IEA];
                     GO_process: GO:0009254 - peptidoglycan turnover [Evidence
                     IEA];
                     GO_process: GO:0046348 - amino sugar catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HHS5223600.1"
                     /translation="MLIKTLENLVTEGRNKNTLQIDKEDTLGIIELINNEDKTVAYAV
                     EEQKESIAKAVNIIVDRMKQGGRLFYIGAGTSGRIGILDATECPPTYGVDFELVQAII
                     AGGNQAIFKAIEGAEDDKELGKQDIIDRGVTSKDVICGIAASGRTPYVIGAMEYAKEL
                     GCAVLSITMNPNSEMSKKADLPINIIVGAEVIMGSTRMKSGTAQKMVCNMLTTASMVK
                     MGKVYSNLMVDVKTSNEKLVERAKRIIMIATNVKYDVAEKFLEEADNSVKLAIFMIKS
                     GLDKDSAKSILDRQEGYISEALKSIEKL"
     gene            156769..157689
                     /locus_tag="KRH23_000302"
     CDS             156769..157689
                     /locus_tag="KRH23_000302"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0045127 - N-acetylglucosamine kinase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine kinase"
                     /protein_id="HHS5223601.1"
                     /translation="MYFLGVDGGGTKTTFTLVDEELNIVGTITKGTCHYNQIGFDNLT
                     KLLITGLEEVCKDAKINVEEITYAFVGLAGYGKIKEVLYALEVATKNAYSHINYTLGN
                     DVEIALAGSLNGEKGINIIAGTGSIAQALDKDGNLHRCGGWGYVLGDEGSAYYIGMAT
                     LKMFTMQSDGRCSKTKLYDLIKRHLNIENDYDIIKYVNDEIQGDRIEIAKFATICLKA
                     VIEGDNTASKIFDDAAYELSRLIIGLEHHFEQGTKIKVSYSGGVFKSGDLILEPLKKY
                     LNKTRFGIVRPVLTPDLGACLLAKKKYYSK"
     gene            157706..158557
                     /locus_tag="KRH23_000303"
     CDS             157706..158557
                     /locus_tag="KRH23_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HHS5223602.1"
                     /translation="MSCILKLKQIYEDLTEVDKKIADYILNNTEAISKLSVSELASNS
                     KTSTASIVRFSRKMGYSGFGDLKIEIAKDLMGKENEYTYVDENYDCNIDSVINKITNK
                     NIETINQTRLLNEKDIIKEAVEQIIKAKNVYIFGVGGSALVALDLQMKLLRINKQAFT
                     SLDSHTQLMVSSNVDKEDIAIAISYSGESKEVIKSIENAKLKGCKVICITKYSDNHLS
                     KISDLKLVVPNIEKRLREGAISSRIAMLTLIDIIYISIIQENLNEAEQKLQETKRILD
                     YLNINNA"
     gene            159168..160229
                     /locus_tag="KRH23_000304"
     CDS             159168..160229
                     /locus_tag="KRH23_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
                     /protein_id="HHS5223603.1"
                     /translation="MKKIRKLATKLLITTIVLISGMSMTVYGMTAKEVTAKTPKSYVT
                     GTNSVYGPKLSQAQLNSVAQATADFMNKKITKNMTTDAKILVAYNHIKNNTTYVDWNA
                     VEGANTAYTLVTKKGACSGMARSMKALCDAMGIESYYVHSTSNDHQWNLIRFGDGRLY
                     HVDIDANKSAGKDIIYKSLSHPLPFDKTAYPKVGAIVQTVKPEQTQKPAPPGKHTMLP
                     HQEGAKAVGNFGKKGEDINEKHVMYEGVRCSVVNSSVNTITFTGSESNLDPSNLTIAV
                     IGFMNTPYGMFALAPEGKPVEYPFKYDKPFSLDFSGKNRSGAELAKYCKKNDVTIKIE
                     ITDEKANIGLGQIMYVRYE"
     gene            complement(160345..161319)
                     /locus_tag="KRH23_000305"
     CDS             complement(160345..161319)
                     /locus_tag="KRH23_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HHS5223604.1"
                     /translation="MNNINSLKVIKLSLGCSLAIFIAWLLKLEYSMVAGVIVLLTVKD
                     TKRETLKGSIGKIYGFLLCTIFSYLCFNILGYNLTSFSIFIFIIIPLCFLLNIQDVIA
                     MCVVIASHYYLQGETSIKWILNEAGIFAVGTGIGVLINMYIPTNIHKIHEVQKKLQEE
                     VSIVLIDIADIIVNPKKENGYSRDLYTLNSLIDSSISETYDNINNTLLSDTRFFLEHM
                     DIIKSQRDILENLYSYVSQLNSTPPQAHILSAFIHKIGYTEFEAETGNLLLEELKRLM
                     LSMKNQPLPVDRTEFENRAILFLCLTELKQFLVNRKHAQMLRDNNFYK"
     gene            161775..162656
                     /gene="pepI"
                     /locus_tag="KRH23_000306"
     CDS             161775..162656
                     /gene="pepI"
                     /locus_tag="KRH23_000306"
                     /EC_number="3.4.11.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004177 - aminopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="proline iminopeptidase"
                     /protein_id="HHS5223605.1"
                     /translation="MKITEGYMPFKGFKTYYRIVGENTEGKKPLVLLHGGPGSTHNYF
                     EVLDKIAESGRQVIMYDQIGCGNSFVEGHPELFNADTWIEELIELRKHLGLDEIHLLG
                     QSWGGMQAIWYAIEYKPKGIKSYILSSTLSSAKLWEKEQKRRISYMSEADQKALLDAV
                     NTGDYSSKEYNDALERFMEMYCAGEVTEDSPECLRRPKKSGSEAYIVGWGQNEFSPTG
                     TLSGYEFTDRLHEIKEPCLVTSGAIDLCSPYIAKTMYDRIPNSKWELFEYSRHMPFVE
                     ENEKYIKVLTEWLNAND"
     gene            163038..163841
                     /locus_tag="KRH23_000307"
     CDS             163038..163841
                     /locus_tag="KRH23_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5223606.1"
                     /translation="MEKLRVIEMIKNNPNIIATIDNPTDEMKLLAIKENGLVLEYINN
                     PTREMQELAIDNNIRAIKFIDNPTEDMMIKAVNEGWSILDYIKNPTDKVIEMAINQAG
                     WAIKYAKNPSEELQLLAVRKNYDSIKFIKQPYESVQEEAVRISYDALRYIDSPSYNAE
                     LIAIKNNEAAISFITDLDKNKILEFLKVNILVIKYILKKVSKDELESVLKEVLSKEDV
                     EEKYIRDFLNCSVIDRNSESIPIDKIMFIYKYGSKTAKKIAVDEKLKIM"
     gene            163853..164983
                     /locus_tag="KRH23_000308"
     CDS             163853..164983
                     /locus_tag="KRH23_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HHS5223607.1"
                     /translation="MNFIDTLKSVDLILSTGEVPLIVGESGIGKTALANKLAKENDWS
                     LIVIDGNLLKEGEIGGLPTIESYVGVNSNGYKTEKKTTVYAVHNKLREIDEEISRSKT
                     VLLFIDEINRCEHTVQQELMNLILNREINGYKLHDDVKILAAMNPSSKYGSDFDYQVV
                     DMDAAQENRFVWLNMESDHTQWIKWAIDEGIERKVIEFISTFPEYLHKINEDDVRATP
                     RSYERVSKIYKVYKEKNNSIPRAVFLNVVKGNVGKVIAEEFISFIESNSEPLISYEDV
                     FLGESIDESIVERVKNESHTRLYLSAMNILKDLELNIKNDKYESNHYINRFIEFLKMY
                     PVDLMIGIMKDIRNSYIEVYKKAIENEEFVKSYFESYSLIRG"
     gene            164987..166396
                     /locus_tag="KRH23_000309"
     CDS             164987..166396
                     /locus_tag="KRH23_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HHS5223608.1"
                     /translation="MENYFDKQAKELYNKASEIINTHSMLKANRANEKFDIDIPQDFK
                     YEFFSLVDKVNLSLMEEEDNFYGYFLFQMSREIRFDISSPTGVNFKGAKYVIYFNPII
                     FLTLDIKQMETTIKHEIHHILSMHLMRAKELKGKYSTLAINMAMDIVVNKFLNNLPPY
                     ATTLEWVNLKYSLKLEPYEPFEYYVEKIQTELDLMEVDEDGEEDDSDKYGDIEIDYSP
                     ERTHDIWDESNEIDENTLREFTEKFINSSQKGKVPAYLESMISSLKNSKGELPWNLYL
                     NRIMGTVENNKKKTITRRNRRQPNRLDLRGELRSHKAEIAVALDVSGSISDEEFKQAI
                     KEVLSIVKNYNHEITIIECDNEIRRVYKVRTEKDIKDRIRIGGGTRFSPVFEYANNKK
                     INLLVYFTDGKGENKLQVIPRGYKILWVISGRGDKISLKEPYGAVKKLTKVKTNDEIL
                     EINDVRNDGYSMNSQAPIL"
     gene            166613..167116
                     /locus_tag="KRH23_000310"
     CDS             166613..167116
                     /locus_tag="KRH23_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140110 - transcription regulator activity
                     [Evidence IEA];
                     GO_process: GO:0009303 - rRNA transcription [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CarD family transcriptional regulator"
                     /protein_id="HHS5223609.1"
                     /translation="MFLFKIDDYIMYGMTGVCKVMDITNERFTNGIKKEYYVLSPIYS
                     NNTVIKIPVDNEKVPMRKLLSKINVLSLINDIPNMDTSWIDNEKLRSEQFKKILRGGK
                     CEELIKLVRSIDNNREYVKSIGKKTHQADDNIMKEAERLLNEEFATILDISPNEVSSY
                     ISSHIPQ"
BASE COUNT        65761 a        17645 c        29590 g        54906 t
ORIGIN      
        1 aaaaacagta tattcattga caaatataag ttttaagtat atattaaaaa ttattagagt
       61 gtatattaag gatgtataca gtgtatatta agaattatta gagcgtatat taggatgtat
      121 acagtgtata ttaaaaatta ttaggggagg gggagtttat gcagcaaaaa tgtaaaaaga
      181 aagcactatc aatgatttta agtatctcaa tgggatttgg gtcagtagca tcatttaatg
      241 catcaaatat tttcgcagat actatagaag aaagtaccaa tgcaggaagt acagaaggaa
      301 atgctaatgc aggaagtgca gaaggagaga ctaatgcagg aaatgcagaa gaggatacta
      361 atgcaggaaa tgcagaagag gatactaatg caggaaatgc agaaggggat actaatgcag
      421 gaaatgcaga aggagatact aatgcaggaa atgcagaagg agatactaat gcaggaaatg
      481 cagaaggaga tactaatgca ggaaatgcag aagaagatac taatgcagga aatgcagaag
      541 gagatactaa tgcaggaaat gcagaaggag atgcgaatgc aggaaatgca gaagaagata
      601 tgaatgcatt agttgtggaa gaagccactg cagaagatcc tacatctgta ggagacttta
      661 aaattagtgg tggagaaata aatgttgatt ttaaatttgc aagtggcgtt ttaactattc
      721 ttagtggaaa acaaatgaca attcaaaata ataatccaaa tactccaaca acacatagga
      781 ttgttatacc taaagatgta aaagctgaat taatatttga tggagtaaat attaaaactg
      841 catctaatag cccatttact ttaacaccag ataaagatgg cggtgcatat gcacatgtta
      901 tattacaaga tggtagtgaa aacaaactag agtcaggtga taaaccttat ccaggtataa
      961 gagcaggaaa aagtaccact ttaattattg atgattctat tgtaaataga gatattgaag
     1021 gagaatttat agttcccgaa aatgggaaaa ttcctagaga tgtaactcta gaaaatggag
     1081 acaagctaaa aaaaggagat cgccttacac tactagatag taaaaatagt gggagtttaa
     1141 cagctgtcgg aaattcttat gctgcaggta ttggtggtgg agatactgaa aatggaggaa
     1201 atattatcat taatggtggt attataaatg ctacagctaa ggaaggaagt aatactgtat
     1261 atggagctgg aataggtgga ggtcgtattg gtgatggtgg agatatcaca atcaatggtg
     1321 gtactataac tgctaaaggc gcatatcatg gagctggaat aggtggaggg tactatacag
     1381 gaattagtat taatatatta aatccatcag tagtagatcc tagctcaggt tatggttata
     1441 gtggaaatat tacaattaat ggtggacttt cctattcata tggaggggca catggtagtg
     1501 catttggaga tggatgtact aagataggag taagtagagg atatcgtgta cttgtaactg
     1561 gaggaacggt tttaccctat ataacaggaa cagaaacgtg gctttctgac ctaagtgctg
     1621 tagcaggaga tgttatagta acaggtggtt cattaaaagc gacaacattc aaaagtaacg
     1681 gtggagtggc tgttgcatat ggtgacttag aaaagaaaac agaagttttt atgaataaaa
     1741 tatctctaac gtatttaggg caagataaag ttaatactac actagttgag gattttaaaa
     1801 tgttaattaa tggaaaaatt tatccttatg gagcacctag ttatacagac gatcaagggg
     1861 ttctttactt atggttttct gatcaattta agaaatctga agtatctgtt aatttagttg
     1921 ttatagataa aattactgga gaaaatataa aaccaaatga tttttatatt aaagatatag
     1981 gttcaggttc tcaatattta aagcaatatg aagaatttac tattgataat actccaccat
     2041 atttgattaa taaaagatat gatggattac catttgaaga agacgtagaa aaaggatttt
     2101 tagattggct tttaaaagat ggtggtattc caataactac tcctgcaggt gaaaaactta
     2161 cagataaaaa atttatgact attagttctc aacgtttaaa cgatgaaacg atggaaccag
     2221 atataaattt aggaagtgat gaatttacaa aacaagttga tgctggaaaa tatcaattaa
     2281 acattacatc gacacagttt tctaatgaat atccttttaa tgaggcttat tgggggcata
     2341 gagcatttta taaggcagaa attattcctg ctgatgcaga aacttcatta gttgtagaag
     2401 agtctaaagt taaaactgat gtttttaaac caacagatac atttacatta aatgctactg
     2461 tttcaccgga taagaaagaa ggaccagatt gtgcctctcc aagaggttac gtacaattct
     2521 atattaatgg aaaggaatat aaaaatccag tagaattaaa aactcataat aagggtagtg
     2581 agagtcataa ttatagtact gcatctattg aatggagacc tttagataac aatcatcata
     2641 tttttactac tgaacaaact attactgtaa aatatattgg agatgatata aattacattg
     2701 aaggtagtga ggatgaaaag aagttaaagt tagatatgac aaatgtagat gtagatgggg
     2761 atggaaaacc ggatataaat atagacactg atggtgatgg aaggccagat atcaatatag
     2821 atacaagtgg tgattggaag ccagatatta acatagatac tgataataca ggtgaatgga
     2881 agcctagtac agaaggtgga aatggagatg gtatttggaa acctgataaa aatatagata
     2941 ccaatggaga tggaaaccct gatacagatt ataatcgtcc agcaatagat gcagataatg
     3001 atggagtaga tgattattgg aagcctgata aaaatgtaga tactggctca ggaggttatg
     3061 atacaggtaa tccagatcca aataaaccag attcaggtaa cggaggaaat agcaaaccgg
     3121 attcaggtaa cggaggaaat agcaaaccgg attcaggtaa cggaggaaac agcaaaccgg
     3181 attcaggtaa tggaggaaat agcaaaccgg attcaggtaa tggaggaaat agcaaaccag
     3241 atatagatac agatggagat ggaaaaccag acatagatat agatggagat gggaaaccag
     3301 atataaatat agatacagat ggagatggaa aaccagatat aaatatagat acagatggag
     3361 atggaaagcc ggatgtaaat atagatatag atggggatgg aaaaccggat gtaaatatag
     3421 atatagatgg ggatggaaaa ccagatataa atatagatac agatggggat ggaaaaccag
     3481 atataaatat agatacagat ggagatggga aaccagatat aaatatagat atagatggag
     3541 atggaaagcc ggatgtaaat atagatatag atggggatgg aaaaccagat ataaatatag
     3601 atacagatga aagtttagat agtaatgtag gtcaaaatgt acaaacagga gatcaaagca
     3661 atataatgct agatttagca ttaatgttca ttagcttgtt ctttttaatt aaaaatctaa
     3721 caaataaata cttaagacgt aaataacatt tattgtgtac atatttattt tattatttta
     3781 ttggataaac tatagtgact ataaatagat ttgtgtaaat aaaaatctat ttatagtcat
     3841 ttttgtattt aacttaaaag ttttgaaata attttcatat agaaaagaga attttttatt
     3901 aaaagagatt aatggaattg atatcattaa ttcaatttta gtagttatgt ttagaagatg
     3961 attttaatct atgtatagtt gtttttgtta gaataataat ttgtaaatac aagccaaaca
     4021 ctcaatatta tgttgagtat ggaaatatga ttgtatattc ttcagataaa aatttgaatt
     4081 tgaagtgata attggtacta atttatggag gttatgttaa aaaatcatag attctattag
     4141 gtgatttttt cagttttata aaaaacaata cccatctgat ataaaaatag atttttttaa
     4201 attaatatct tttatactat taaaccatta aagatgatag tctttcctca taatatattt
     4261 atggaagaaa gaagatttag acttattgta ataatattca agggaggtag ctgaaaatat
     4321 atcaactaaa atagatatac tactatgtaa tttaatggat aacttaacta tagaaaaaga
     4381 ctatctataa atatttgaaa taaatcttag tataaattat tagcagttta ctaatgtttt
     4441 tttgtaaaaa atcaatcaaa aagttatata ataactttat ataacaaata gaaagaggtg
     4501 aaactacatg gctaaaattg acaatatgat gtctatactg tggatgttaa actctgacaa
     4561 aaaaattaca gcaaaacaga tagctgaaaa attagaaata aatataagaa cagtgtaccg
     4621 atatattgat gtactttctg cgagtggagt acctataatt tcagatacag gtcataatgg
     4681 tgggtatagc cttttaaata attttactaa agcacctctt ttttttgata tagaagagca
     4741 aaaatctcta cttcatgcag cactatttgc taaaaaagaa ggatacttct tagacgaagc
     4801 attagataaa tcgatattaa agttaaaaat gtattcaaat caaaaacaag aagatatttt
     4861 aacaaaccac ttaatagccc ttgaagtaat aaaaccaatt gggaaagtgt ctatagaatc
     4921 agtacttaaa aaattggaga atagtatatt aaaggagcta tctgtagaaa tcaactatca
     4981 tgcaggtcgt aaagcaaaat caaaatatag aattataaat ccatatggaa ttgttcactg
     5041 gaataataat tggtatgtag ttgcattttg taatatgaga aatgaggtac gtagtttcag
     5101 agtggatagg attagtgaaa tcatagaaac atcaaataca tttaacagac cgacagaatt
     5161 ttcagcaagt gaatttttta taaaaggaat tatacctgaa ataaaagatg aacaaaatat
     5221 aattcaatta gttgtagaag ggagtataga ttctttagat agtttaagcc aacattggtt
     5281 tttagggcac tacttgaaag aaagaacacc taataaaata atatttatgc ttgaagagga
     5341 agtaatatgc aagtacatac caaatatact tttaccttat agaaagacaa tacaagtaat
     5401 tgaaccatta agccttagga agaaaataat tgaagattta ctagaattaa ttgattatta
     5461 tcaaatttaa tagcttaact gactgaatat gtcagttaag ttattttata attagatata
     5521 taaattaatt acataaggag taaaaaagat gaaaaataga aaagtatata tgtatgtatt
     5581 tgatactatg tcagattggg aagtggcata tttaactgct gaattaaata caggaagata
     5641 ttttaaaaaa ggattaaagc cattaaaagt aattactgta ggaattgata aaaatcctat
     5701 tataacaatg ggtgggttaa aagttttacc tgaaattaca gttgatgagt ttaatatgga
     5761 aagtaaggat ttattaattt tgccaggggg aaatacttgg ttatccatga atcatgagat
     5821 aatattagaa aaagttaaag aagctttaat acaagattct atagttgcag ccatatgtgg
     5881 agctacatta ggcctagcta aaaaagggct attagatttt agaaatcata caagtaatga
     5941 cttagagttt cttaaaatgg taataccaaa ttactctgga gaaaaatatt ataaaacgga
     6001 atctgtagtt agtgatgaaa atttagttac ggcttcagga attgctccgt tggaatttac
     6061 gtttcaagta ttgaaacttt tagatgtttt tgaatcagaa gcattaaatt catggataaa
     6121 tctttacaaa actcatgact caaaatattt ttttgaatta atgaattgta acaagtaaat
     6181 ttaaaattta tttttcaatt taatatggta tagcattgtg atataaagaa caaaaaatta
     6241 caatctggtg gaatagagta gtggtttcta atatagattt ctttttggtg aatttaaatt
     6301 ttatttaaat ttaaattcta aaccactttc tatatagcaa tagaaaagtg ttaaaaaatt
     6361 atcatatata taattactac ttatagcaac acaaatagag ctaataactc ctataataaa
     6421 atttatcatt agttacatat agaataaacc tcagttttga ttactgtagg aactaggatt
     6481 atatgaagct accactcata gatttcagtt ttttctgttg tatcatagca tagaatagta
     6541 aattcatctg aaactttatt ttaaatttag aatttgcata tagataaatt atgggcatta
     6601 ttctgatgat tcgtctccaa taattaaaaa aagaatgata aaatacttga aaatactagt
     6661 ctttattgac tagtgttttt ttatttcagt gataaaatat accaattata cttcagttac
     6721 aggaaatgat gtttttgagg gtacattggg aggcatttag gttgtataat tataaatttc
     6781 aatgttatat gctcattaga ataatagtta gtaaatgata tgattgagat aatagatgaa
     6841 ataaactaat ttagtactgt attgtagtgt ttattataaa atcttttata aaatatattt
     6901 atgaagatat tattgaatat tttcaatatt ctattgcaat ttatttggaa aagttatata
     6961 tttataacat aaggtgttat aaatatataa cttttaaggg gtgattttat atgtctaaat
     7021 cagagcttgg tgttaaaaca aatcttgttt cagagttact tatgatatcc tattttttta
     7081 tagactcatt attaaaaaag tttattttta aagatggaaa tctttgtatt acttttataa
     7141 ttttattcgc tttttgggca tgtgacttca tgtataataa aaaatataat gatttagttg
     7201 acgaggcgtc aaaacttatg ttattaaagg ttgatcatat tgcatcaaaa ataatgttat
     7261 attctatttt gctaatagct gttttctttt cagcaaatta tacaagaggt ttggatatat
     7321 caaatttgga tataggtata attctcttag ctattttatt tatacaatct ttatctaaat
     7381 taattttgta tatacatttt gatagaaagg gaatatgcaa ctaagtgata atattgataa
     7441 aaacgaaaat taaagagtat agagaatata atttttaagg agtgatttta tatgtctaaa
     7501 tcagaaactg gtgtaagatc aaagcttatc ctggagttgc ttgtaataac ttattttttt
     7561 atagctgtat tagccactaa gtatattttt aaaggtccaa gcactgcttc tcttccaggg
     7621 ttgagttggt taatagtttt tggatgttat tcaatctata ataaaaaata taatgattta
     7681 gttgatgaat catctgaatt tatactatca aaggttaata agattgcaat aaaaataatg
     7741 atatattcta tagtaataat atctattttc tttgcaacac cttatacaag taatataaat
     7801 atatcaaacc tagatacagg tataatcctc attgcagttt tatttataca gtctttatct
     7861 aaattagtgt tgtatatata ctttgataaa agggggatat gtaactaagt ggcaatattg
     7921 atgaaaacaa aaattaaaga atacagagaa aaactcctta tgacgcaaaa tgaacttgct
     7981 aaattggttg gggtaagacg tgagactatt gtacacttag aaaatgggaa atataatcct
     8041 tctttgaagt tagctatgga tatcgctaaa gtattcgata ctacagtaga aaatttgttt
     8101 gaatttattg aagaagaata gtggaaagtt tataaacatt tataagatag ataatgaaat
     8161 atagttattt aattattaag tttattaaaa atatttatat aatatgtgat taaggttaga
     8221 ttataattgt tttaagacaa taagaagagt attataaatg ataaaaaata gtgaatatac
     8281 agttaattaa taaacaatag ataaaaattt aaagttcaaa tataaagagg atgtatagtt
     8341 ttatgaaatc taataagata ctgttataat cgctatgtaa ggaaatcata ttagaatttt
     8401 ctaagaaaac aggtaagaat ttggaagtaa gtatgggtta tttatatact tctgaaacat
     8461 ataaactaat aagtgaggtt gtatcagata tgtcttgtaa gggtaatttc ttcaggttca
     8521 tcaactatca taactctaca gagggtataa gatatgcttt gtaagggtaa tatatgcatg
     8581 attcaagaat tagtgttata aaatggatta gcataccaaa aggtctatta aagatataca
     8641 gttaaaaaac tatatagtaa gttaggtaag gttaataatc caaacaatga tttgataatt
     8701 aaactgttta gagcctcaga tacaacagta aaagaattat tttttaataa ggagaagtaa
     8761 aagataaaag aaaatcaaaa cttaggcagt tattgtagtt acaaaataaa ggatttcctt
     8821 atatatggat aaataatcga gtatatataa taaaaaatat atgaccttaa ttttgttatg
     8881 aaataacttc aaaacttatt ttaacatgtt tagattatat aaatcatata aaaaaagtag
     8941 aatgagtgaa tacttatgac aataatctag tagagatata catgaaatta tatattgact
     9001 aagtacagtt attaatttat aatgaaaata aagttatcat acagataaat aaacggatcg
     9061 ttactgagat agatgtaatc aggcgtgacc taaaaattct agtaaatgct taaagtatta
     9121 ttagtctttt ttaggtctct ttttgtttac agtggaggta gtttatggtt ataaagaaag
     9181 tatttaacaa caatgttgta tttgccagag ataattcagg acaagaagta atattaatgg
     9241 gaaaaggaat tggatttaat aaatttacta aagatttagt tgaaatagat aaaattgaaa
     9301 agaaatttat attcaataat gaggaatcat taagtgaatt acattcacta ctagatagga
     9361 tacctttaaa agatgttgag cttgtaagtg aaattattca aatgggaaga gaagaattgg
     9421 gtgataatct taatgatagt atattaatca cattatcaga acatataagt tatatgttaa
     9481 aaagaatgga tgaaggatta gtatttcaaa gcccgcttca atgggaaata agacaaatat
     9541 atcctaatga atataatttt agtaagaaag ctgtagaata tttaagaaaa aaattagata
     9601 aaaatattcc tgattctgaa atagcattta ttacgataca ctttgcaaat gctcagttag
     9661 aaacaaaaga tatgcaagaa actttattgt taactaagat aattgataat gtattagata
     9721 tcataaagta tcactatgga atcgaaataa atgaatattc ctttgactac acaaggttta
     9781 taagtcattt aagatgtttt ataaaaaggc aattaagtgg tgagaataca aatgtagaca
     9841 catcattgtt agatataata aaaatgaaat ataaaagtga ttacaattgt gcaaaaaaag
     9901 taaaaaactt tcttgaaaag acgtataaat ggaaaattag cgaaaatgaa ttgttgtact
     9961 taacattgca tttaaataga ttatcaaata taaagtaaat agtgtaggat tgttactgtt
    10021 tggcaggcat gacctaagtt ggtataatta gtttttaata tctaattgta ttgatttagg
    10081 tctattttta tacataaaat tatgaaaatg gaggatagat tgtatgaaat ttgaaagaga
    10141 gtctgaagaa attataaaat atgtcggagg aaaagaaaat attattagtt tagttcattg
    10201 tgcaactagg ctacgtttta agctgaaaga tacttcaaaa actaacaaag aagagttatt
    10261 aaaaatgaag gatgtactat ctgtagtaaa tagtggagga caataccaag tggtaattgg
    10321 aaataaagta actgattact ttgaaactat tataaaaaaa gcagttttac aaggacaaaa
    10381 tactgaagaa cagggagaaa aagtttcaat agtttctaaa atatttgaat caatttcagg
    10441 tgcattttct ccattaatac ctgcactagc tggagcagga atgattaagg cactgcttac
    10501 aatactaact actatgaaat ggatgtctga tacaagtagc acttatgcta tattatcagc
    10561 agctggaaat gctgtatttt actttttacc aatattctta ggtattacct tagctataaa
    10621 acttggtgca aatccatatg ttggtggagt gataggagca gctttgttag atcctaattt
    10681 tacagcttta attggagcaa aaggtggtgc taactttttt gggatgccag taacagcaat
    10741 tgattattct tttggtgtat tccctatatt tgttgctata tttatttatt actatgttga
    10801 taagctttta aagaagatta tattaaagga tttacaatta ttcttagtac cgatgatatc
    10861 attattagtc atggttcctt taactgtgat tttatttgga ccaatagcaa ctaatgttgg
    10921 tgatataata tctaatattt ttatgggatt atttgaattt aacagagtaa ttgcaggagc
    10981 tgcaataggt atagctatgc cattcttagc agtattagga ctacactggg gcttcacacc
    11041 aattactttg caaaacttgg ctacaatggg tggagaccca atagaaggtg cagctgttgc
    11101 agcagtattt gctcaaatag gtattgcaat aggtttattt atgaaggtta gaaaatctaa
    11161 aaaaaattca gaattaaagg tattagcagg ttcaacagca gttacaggaa ttttagcagg
    11221 agtaacagaa cctataattt atggaattat attaagatac agaagaatga ttccagtatt
    11281 ggctattgca ggaggtattg gtggtggtat atgtggtgta tttggtgtta cttgtaatgc
    11341 atatgtattc cataatatat tctcaatgcc agtttataca ccattcctag gatatatatt
    11401 aggaatagga acagcattag tgctaggagc agtattgtca tatttctttg gattgagtaa
    11461 agaagaatgt gaagaaggta atgaagaagt tgcttttgat gaagatgatg gtatagagga
    11521 aatattatct ccaatagaag gcttacaaat agagttatct gaagtagaag atgaagtgtt
    11581 tgcatcagga actataggta atggcatggc aataatacct tcaaagggag aagttgtgtc
    11641 tcctgtaaat ggaacaataa caactatttt tcctacaaag catgcaatag gaattacctc
    11701 tgataaaggt gtagaaatat taatacacgt aggtcttaac actactatgt tagatggaaa
    11761 gtattatact actcatatga atgcaggaga taaagttaaa aaaggagata ggattgtttc
    11821 tttcgataag gataaaatag aaggtgaagg gtatagtatt gttacaccaa taatactaac
    11881 taacacaaat gatttagcag atgtaatagt taaagaaaat aaacatatta aaattggaac
    11941 gcctgtaata aaagttgttt attaattata ctggaggaga tatttctatg aaatctaatc
    12001 aagaattttt atggggaggg gcagttgctg cccatcaagt tgaaggtgga tataataaag
    12061 gtggaaaagg aataagtatt gcagatgtga tgactgcagg tactcatact atttcaagaa
    12121 agataacaga tggagtaatt gagggtttaa attatcctaa tcacgaagcc attaattttt
    12181 atgaaaatta taaagaagat attagattat ttgctgaaat gggatataag tgttttagga
    12241 caagtattgc ttggactaga atttttccaa agggagatga atcaactcca aatgaagatg
    12301 gattgaaatt ttatgatgat ttatttgatg aattattaaa atacaatata gagccagtaa
    12361 taactttaag ccattttgaa atgccttatc atttagtaaa aaactatggt ggatggagaa
    12421 atagaaaatt aatagatttc tttgtaaact tctgtgaagt ggtaatgaat agatacaagg
    12481 ataaagttaa gtactggatg actttcaatg aaataaataa tcaaagtata actacaaatc
    12541 ctatttatgc atttactaac tcgggaataa tctatgaaga gcaggaagac aaagaagaag
    12601 ttatgtatca agcagttcat tatgaatttg tagcaagtgc aaaggttgtg aagataggtc
    12661 atgaaataaa ccctgagttt aaaattggat gtatggtggc agctatgcca agttatcctt
    12721 attcttgcaa tccagaggat atgattaaat ttgtagaatc taatagagaa caacttatgt
    12781 ttactgatgt acatgtaaga ggtcattatc caaaacatac actaaaatta tgggaaagaa
    12841 aaaactataa tttagatatt acagaggaag ataaaaaaat cctaaaagaa ggaatagttg
    12901 attttattgg atgtagttat tatttaacta ctgtagtaac agctgataaa actatgaaaa
    12961 caacaggtaa tgactcggca ggaaaggctg atgtaattga aaatccatac ttaaaaactt
    13021 ctgactgggg atggaatata gaccctgtag gtctaagatt ttaccttaat caactatatg
    13081 ataagtatga acttcctata ttcattgttg aaaatggatt tggagcagaa gatgtattaa
    13141 aatcaaataa tactgtggat gatgattata gaatagagta tttggctagt catataaggg
    13201 aaatgaaaaa tgccattgaa attgatggtg ttgatgttat agggtatact gtttggggat
    13261 gtatagaccc agtatcattt acaacaggag agatgaaaaa aagatatgga tttatatatg
    13321 tagatagaaa taatgatgga agtgggactc ttaaaagaca taaaaagaaa tcttttgatt
    13381 ggtataaaaa tgtaataaaa tttaatggag aaattttata ggtagataaa ttttaatatt
    13441 tataagatgt taaggaaacc attaaaaatt agattaaaat cgtgggtatt taaatccact
    13501 aaaagatatt gactatttag tcaatatctt tttttattaa aaagtaaata taaagaggta
    13561 aggttaaaaa ttgggatata tatgatttat atagtatgat ttaattagaa ggagctatat
    13621 tagtattcat ttgaacagtt ggagaataaa tgtcagcctt accttacgtt ttttataata
    13681 gtcctattta atttctattg taactaatat gcaagaattt aagatagaag tatctatgac
    13741 ttatggtgta ttagtaattg gtatctgcta tctagtatct ttttaatttt tttgattcca
    13801 atatagtact aactacgata cgaatatctt taaatttata gctaaactat ctaattgttt
    13861 attggaaaga gttaagaagg ctaaagcata aaacacttaa aaagagaaga tgtacatgag
    13921 aaatataatt aactatgata cagacttcta aaaattattt agtgaaaagg aacttagagt
    13981 gtataataaa agttcctttt cactaaggaa aacgattgtt attttctgac cttcattacc
    14041 ctgatattat ttaaatataa acaacaacaa aattaacaag aagcaaattc aaactaaaat
    14101 ttaaaatatc gggaggtaca atatgttaat aaatatgaag gaaatgctaa aagtggcaca
    14161 agaaaatcaa tttgctgtac cagcatttaa tataggaagt gggcaaatac ttaaagcagt
    14221 agtacagagt gctaacgaaa aaaatgcacc agtaatactt gcaatacacc caaatgagct
    14281 aagttttcta ggagatagtt ttgtagctag ttgcatagaa gaagcaaata agagtaaagt
    14341 acctatggta atacacttag atcatgggga aaataaagaa caaatattaa gggcaataag
    14401 atgtggattt acatcagtaa tgattgatgg ctcacattta ccatatgaag agaatgtagc
    14461 tatatctagg gaaatagtag aaatagcaaa aggattaaat gtgtccgtag aaggagaact
    14521 tggaacaata ggaacaacag gaacatcaag tgaaggtggt actgatgaaa taatatatac
    14581 agattcaaaa ttagctaagg attttgttga aaaaacagga gtagaaacac tagctattgc
    14641 aattggtaca gcacatggta tatatccaaa aggttttaaa ccagagctta aactagattt
    14701 attaaaagaa ataagagaag tagtagatat acctttagtt cttcatggtg gttcatcaaa
    14761 tccagatgaa gaaatagcac aagcagttaa actaggagtt tgtaaaataa atatttcgag
    14821 tgatgttaag tcggcatatt ataagaagtg cagagaacta ttagaacaaa acccaagctt
    14881 atatgagcca gatactatat atccaccatg tataaaagct gcaagagaag ttatagagtt
    14941 taaaatgaat ctattcaatg ctatagataa gttaaagtgc ttttataaaa ataaaaatta
    15001 attatgaggt aacaaattaa aaggagggga gaatttatga taggtaaaat actacgaagc
    15061 gattgtattg tactagataa acaattacaa acaaaaaaag atgtaattaa ttatatggca
    15121 aatcatttgt accatggaaa ttatataaat aataaagaaa agtttatagc tgatattaat
    15181 aaacgtgaaa aagaatcatc aactaatatg ggtaatttaa tagctatacc tcatgctaag
    15241 tcaaatgtag taaatcaacc tgtaatgatg tatttaagaa cagatagaga gattacagat
    15301 aatgatggtc aaaaacttag gtcatttttt atgatagcag ttccagaatc aggttcagat
    15361 gaacatctta agattatatc taaactagct acatatctaa tggaagaaaa ttttcttaag
    15421 catctactaa gtgcagaaac tccatacgaa atattaagta tatttaataa taaagctgca
    15481 gaatcaggag attttagtaa taatcaaaat aaaggtctta tagttgggat aacaggatgt
    15541 ccaacaggta tagctcatac ttttatggca aaaaaagcat tagaggaagc aggtcaagaa
    15601 cttggatatg aagttaaaat agaaactcat ggagctatag gtgtagaaaa taagttgact
    15661 aaagaagata taaaaagagc tgaatacgta ataatagctt gtgataaaga agttcaactg
    15721 agtagattta taggaaagaa agtgctacaa aagaaagtag tagatgctaa gaatgtttca
    15781 ttagctaaaa atttaattat aaacgctgaa aatggaatgg ctaaagaaat taaaccaggt
    15841 ggaaagactt tagaagattc aaaagaaatg cttcaagggt cagagaaaaa gggtgtttat
    15901 aagcacttaa tgagtggtgt atctgaaatg attccatttg tagtgatagg tggaattggt
    15961 atagccatag cttttatgtt tggtatattt gcatcagacc caactcatga aacatacaac
    16021 cctatagctg gattctttgg acaacttgga ggcgattcag catttaagtt atttataccg
    16081 atacttgctg gttttatagc taaatcaata gcaggaagac aaggatttgc tcctgctatg
    16141 atagctggtt ttatggcagt tattggaggt tcaggtttta taggtggtat ggtagctggt
    16201 tttgcaacag gatatatagc tttaggagta atgaagataa cagaaaattt accagatgta
    16261 ttaaaaggag taaatgctgt attgatatgt ccacttttga ttgcatttac gagtggagct
    16321 ataatgttct ttgtagttaa tacgccagca tcatggttaa atgaagcttt acaatcttgg
    16381 ttacaaagta tgtctggaac taataaagta ttattaggtg caatattagc agggatgatg
    16441 gcatcagata tgggaggacc tattaataaa acagcttcag cttttggatt ggctatgttt
    16501 tcaagtaata tatttgaacc atcagcagca ttaatggtag gaggaatggt acctccatta
    16561 gcaatatcat tagctatgtt aatattcaaa aataagttta ctaaagaaga aagaaagtca
    16621 tctctaccaa ctgctataat gggggcatct ttcataacag aaggcgcaat accgtttgca
    16681 gctgcagacc cattaagaat gattccagca aatataattg gttcttgtat aggtggggca
    16741 atatgtatga gtttagatat aactttaatg gcaccacatg ggggaatatt tgtaatacca
    16801 tttgcatgta gtgcaccagt tgcatatata gcttgtatat tgattggtac agtaataaca
    16861 gcattgatta taggggtaac aaagcctact ataaggagtg aaaatagtaa agttgaatta
    16921 cttggtgctt aaattataaa taatagtaaa aataattaat ggaataacaa caagtatata
    16981 gaataataat aaggatattt agaatcagtt aactacttct aaatatcctt aatttttatt
    17041 ttgaaattat attatctatt atatcaattt agtaaggtgt atcataaatt cttttatgat
    17101 acagaagtat cttagtaatt ttacatagtt agtaaatatg ttaaaatagt acttaatata
    17161 aacatagaaa tatataaaca taggtaggga gggctaagta tgcttgtgtc gaggcaaatt
    17221 gaatttctta aattgatact aaacgaaaat aaatatagac ctataaaata ctttaaagat
    17281 aaattaaatg tatctgataa aactttacaa aaagatttga agatgattga gaaatattta
    17341 gaaactttta atataaaaat tgatataaaa agaggctatg gaatattaat agaagattta
    17401 gcaaagaaga acatagactt aattaatagt ttaaatatac aatcgaagga aaataaatct
    17461 ttatcagtag agcagagaag aatggagatt ttaaagtatt tattgctaaa ttcaaataat
    17521 ataacttcaa taaatcagtt agcagataaa tattatgtaa gtaaaacttc tatagtaaat
    17581 gattttaaat atatagaggc atggataaaa gaatacaatt taaaacttaa taaaacttta
    17641 gaaggaacta agattatagg taaagaagtg gatataagga aatcgattgc caaaatgatg
    17701 gatgatttat tagatgaaaa ttatgaacaa catgatatat ctgagttaac aagattagat
    17761 tctgctacat ttagtgcatt gataaattta tttgatattg attctattat atttgtagaa
    17821 actataatta cagaattaga atacaattta ggatatacta taaatcagcc ctactatata
    17881 aatttaatta cccatatact tatatgttta aagagaatcg aagaaggcaa tcaaatagaa
    17941 tctcaggaag aaagagaaat ttctgtagat aatttggacg agttagtata taaaaatgtc
    18001 agtatactta tagataaaat agaaaataga tacagagtaa aaataacgaa agatgaaatt
    18061 atgtacatat atattttttt ggtatcatct ggatttagta gcgaaaataa tagtagttac
    18121 aatgatgaat cagatagatt aagtgaaagt gaaaaagttt catctataat gatagagaat
    18181 atgtcacgat ttttaaatat aaatctcaaa aatgatgact tactacagaa aagtctagca
    18241 tctcatgtaa ggcctatgtt aaacagatta agatatgata tccaaataaa aaacccgttg
    18301 ttaggagaga tacaagagcg attttcagat gtgctgggat tatgtatgat gactataaat
    18361 attatgacag agtatgataa tttgaagaat attagtatag atgaagtctc gtatcttgcc
    18421 acatattttc aagcggcaat agaaagaaat atgagtagta aaagagtaat agtagtttgt
    18481 catacaggat atggaacatc tcagctcctt gcagccagat taaaaagaga atttcctgaa
    18541 tggactatag ttgatatagt tcctatgcat cagttgagta agcgaaattt agatgatgta
    18601 gactttgtaa tatctactgt aaacttagat ttgaaagata aattacatat agttgtatca
    18661 gtactattaa tggaaaatga tattaataat ataaaaaatg ctttactttc taaacctaaa
    18721 aaaagtatga acttagatac aaacttatta ggaatgtatt tagaagataa tatatatttt
    18781 aattttgatg tagctcagat ggaaagttta ataggtgtga atttagggag taaatatgaa
    18841 tctatttcat taggaaaaga tttaaatata tatatacata agcaaagtaa attaaataaa
    18901 gagataatga atatcaataa tgttactaga acgattgata tttatttaga aattagtaat
    18961 caaagttttt taaagaatat tttaatggaa atatcaaatt tatataggca aaagaactat
    19021 ataaactata taatagattg caagagcaaa gaggatatta aaatattatt taagaataat
    19081 ctattggaga aaacaaatgg aaattagaga aatattaaca gaagaaagca ttattttaga
    19141 tttgaaatca actacaaaag aaggcataat acaggaatta gtagataaat tatacgatac
    19201 aggaagtata actttaaaaa gtaagtttat aaaggcatta aaacatagag aaaaaatagg
    19261 ctctactagt ataggttatc aaatggccat gccacatgga aaaacaaaat atgtaaagaa
    19321 ggcctctgta gtaataggta aatctaaaaa aggtgtagat tggccaagta tagatggctt
    19381 acctgtaaaa gtaataatta tgtttgctat gccacaatct ggaggcaatg aagatatgat
    19441 attaatatct aaaatagctt acattttagg tggtaaaaat ataggtgaaa gacttttaaa
    19501 tgcacataca aaaaaagaaa tattagatat attttatgaa gtgtaggtat tgtataaatt
    19561 ataaatttga ggtttttaaa ataaaatgtg tattctttta aatagtatag attaattttt
    19621 agacactaga gaggagagga tatatatggc aatatattta gaaatgccta aattaataca
    19681 tgaatttcct tttcgtactc tatcaaatga aggagaagta ttaacaacac cacactggca
    19741 taaggaaata gaaatattac ttataacaga aggtgtagta aatctattta taaatgacaa
    19801 gcctatgcaa ttaaaaaaag gcgagatagt gataataaaa ggaggagata ttcattatat
    19861 actgccatca ccgggaagtg aaagattagt atttcaattt gatatatctt tttttaatga
    19921 tttaatttta ttaaatgagg aaaaagaaag cttaattaat ttattcagta gtataaaaaa
    19981 atgtagtaga gattggtcag caaaaataag aaagtcagtt ttcgatatat tgatagatat
    20041 ctacaatgaa gacctataca aaatagaagg atatagttat gcaataaaag gtaaaatgta
    20101 taatttaatt cctatattat atagacagat tcctagagaa attgaagaaa atacagtaga
    20161 atatgaaata aactctaaag agatattaga gagattgaac aatatattca aatatgtaga
    20221 aaaaaattat aaacaaccta taaaattaga agatgtgtct tatgaagtag gatttagtgt
    20281 atattatttt actaaatttt tcaaaaaaaa tacaggaaaa acatttataa cttttttaaa
    20341 tgaatataga ttagaaaaag caaagtggat attacttaat aacaatatat ccattgtaga
    20401 tttggttgaa gaagttggtt ttggaagtac aaaaactttt tacagagtat ttaaagaaaa
    20461 aattggagtc tctccattag aatttaaaaa aagatataat agcttggaga aaaaagggag
    20521 tgtctcaaaa tgaacttagt tcatgaggca ctttctttta tatgaaatca aatatatttt
    20581 cagtatttca acaatgaaaa ttccattcat ttataaagtc taaattttag ttctcaatac
    20641 aacctctatt tcgaaataaa tccttttata tatataaata tacagcaata tatgagaata
    20701 agataacaat aatgaggata taaaaatgta tttgctatat atataattat atacatagat
    20761 atctaatatt gatatttaat atgaaagtat tgaaaataga caatattaat tatagtgagt
    20821 aaaaaatata attggatttt taaattgaat tatttaaaag gtatagtatg aaaaaaatct
    20881 tataactaaa tatgagatag aaattataaa actttatatt gtgaaagagg tagatgcatg
    20941 aaattaggga aagatttttt atggggaggg gcaatttcag ccaatcaaag tgaaggattt
    21001 tatttagatg gaggaaaagg tttatctcag tttgataaac tcccattaaa tgataagaga
    21061 ttaaaagatg tatgtttaga tgaggataat attttaaatg aaaataatca atactatcca
    21121 agtcatatag ggattaaatt ttgtgaaaat tacaaagaag atatagcaat gttagcagaa
    21181 ataggtttta aatgttttag attttctata tcttggtcaa gaatattccc aacaggagaa
    21241 gaaagtgaac caaatgaaaa gggattacaa ctttatgata atataataaa agaattaaaa
    21301 aaatataata tagagccatt aataacgata agccactttg atatacctta ttctctagtt
    21361 gaaaaatatt ctgggtgggc tgatagaaga gtggttaatt tatatgtaaa atatgctgaa
    21421 attttgatga aaagatataa agatgatgtc aaatactgga ttccttttaa cgaaatgaat
    21481 atgataatgc atattccata tataggtgct gggttaactt ttatagctga tgaaaatcaa
    21541 cttcagaaaa aatatcaagc agcacaccat caattattag ctaatgcaaa aactatagaa
    21601 ataggaaggt atataaataa agaatttaag tttgggtgta tgttagctgc tggaaaaaca
    21661 tatccataca catgtaaacc agaagatgta tttgcaactt tagagcatga aaggcataat
    21721 ttgttttttt ctgatgttca agttaggggt gtgtatccaa gctttatgaa ttattattta
    21781 aaatcaaatc aaataaaatt aataataaaa gaggaagatt tatcaacact taaggataat
    21841 actgtagatt ttgtatcttt tagctattat tctagtgctt gtagttcagc tagagctgaa
    21901 ggtttagaaa aatcaaaggc aaacggacca gaaaccataa aaaatccata tcttccaaaa
    21961 tcaaatagtg tatggcaaaa cgaccctgta gggttaagaa taactatgaa tcagttatat
    22021 gaaaggtatc agttaccttt atttatagta gaaaatggac tgggtactca agatattgta
    22081 aatgaagatg gaaaaataat tgatgattat cgtatagatt acatgaaaga acatattaaa
    22141 aatatgattc ttggagtaaa tgaagatgga atagagctta taggatatct tatgtgggga
    22201 tgtatagatg taaccagtgt aagtgaagga aagatgacaa aacgatatgg cataattcat
    22261 gttgattctg atgactatgg aagaggctca tttaaaagaa ctaaaaaaca aagtgctttt
    22321 tggtataaaa aagtaataga aacagatgga gaaattttat ttaatgatat ggaaactcat
    22381 gcataattca ttttaagaaa ggagtgttat tatgagttta atatttacta ctaaggacca
    22441 acttatagag caagggttta gtaaggatac aataaaatcc aatgaaacgt tgtttacact
    22501 agctaatgga catttaggag ttagagggaa tattgaagag tctgatttta ataatgagta
    22561 tgtagataat atgggtacat atgtaaatgg attttatgaa gaatctccaa ttacatatgg
    22621 agaaagcgct tatggctatg caaaacaaaa tcagactatc tgtaagttac ctaatgctca
    22681 tatagtaaat ttctctattg aaggagatta ttttgattta tcaaaaggta ttacaagtga
    22741 acattctagg atactagatt taaatgaagg gattcttaaa cgttcattta tatgggaaaa
    22801 ctctcgtggt agaaaagtta aagtatctat agaaagatta gtatcacaag atatagaaga
    22861 attaatgatg atttcatata caataacacc attgaatttt aatggaaaaa taaaatttaa
    22921 aaataaaatg gaaaatagta tggagaagtt taattgtgaa aaagtagatg acccaagagt
    22981 ggcatctata aataagaagc aatttaaaat taatgtaaaa aaatataaca ataagtattt
    23041 tatgaattta gttacagaaa gaagtagatt agggttatgg tgtgggtttg attcatatat
    23101 tacttgtgga aatattacaa atgagaccta taatgtttca gatgaatgta ttgagcgaga
    23161 aatagaagtc tatgccaaaa aagatgaaag gttaaattta gaaattgttg taggctatag
    23221 tagagtatat tctgatttaa atctaaatga agaacgttta aaatcattag aatgtctgga
    23281 gtcgttaaaa tgtttagaat cagaagcaca tttaaaatca ttagaattgg ttttaagaga
    23341 agcatgtaat attggatttg ataaagtcaa aaatattcag agaaagaaaa tgaatgagtt
    23401 ttggacaacc tctgatgtag agattgaagg cgataaaact cttcaactgg ggataaaaac
    23461 caatttattt catatttatc aatcagcagg aagagatgga aagactaata tatcagcaaa
    23521 aggtcttaca ggtgatggct atgaggggca ttatttctgg gatacagaaa tgtatatatt
    23581 accatttttt atatatactc aaccatccat tgctagagct ttattagatt atagatactc
    23641 aatcttagat gcatcaagag aaagagctag agaacttgga ataaataaag gttgcttata
    23701 ttcatggaga actataaatg gtaatgaatg cagtgcatat tatccagcag gaacagcaca
    23761 gtttcatata aatgcagata tagcttatgg tgttagaacg tattttgaag caactaatga
    23821 tgaagaattt atgatgcaaa atggcttaga aattcttata gaaacatcaa gattttgggt
    23881 tgaatttgga gattatatag aatcaaaaaa taataaattc tgtataaatg gagtaacagg
    23941 accagatgaa tatacagcaa tagtaaacaa taattactac actaatttaa tggctaagta
    24001 taatttaata tatgcagtac agatggtaga taaatttaag cataatttat tttcaaatga
    24061 agtatttaga aaagttaaat tacaagaata tgaagtgaaa aactggataa atgccgctca
    24121 aaatatgtat ttaccatatg atgaagagaa gaaaataagc aaacaagacg attcattttt
    24181 agaaaaatca gtatgggatt ttaaaaatac accaaaagaa aaatatccat tacttctcca
    24241 ttatcatcca ttaacaatat atagatatca agtaaataaa caagcagata ctgtactttc
    24301 agcgttgctt ttccctgatg agtttagctt agaacaaaag aagagagatt ttgaatacta
    24361 tgaaaaaata actactcatg attcatcttt gtcaaggtca atatttggaa tgatggcaag
    24421 tgaaattgga aatcatgaaa aagcttataa ctattttatg gacacagcat taatggatat
    24481 taataaccta caaaaaaata caagtgatgg aatacatgct gctaatatgg gtggaacatg
    24541 gatgagttta gtatatggat ttgcaggaat gaaaataaaa aatgataaat taagttttga
    24601 accaaggata cctaaacact ggaaaaatat taaatttaat atattattta gagataattt
    24661 agtttctgta aatatagaag aatataaatc ttattataag ttaatcaaag gtagaaatat
    24721 aaccatatta catgataatg aagaaataaa attatcaaag aacataatag aagttaataa
    24781 ttgttttaaa gggagtaatt aatatgaaag cagtcttatt tgatcttgat ggagttataa
    24841 cagatactgc taagtatcat tttgaagctt ggcatgagat agcaaaatcg ctagatatag
    24901 aaatagatga aacttttaat gaaaaattaa aaggcataag cagggaagaa tcattagata
    24961 aaatattgtt atctgctaat aaagtagata gttatactaa agaggaaaag ttaaaggtgt
    25021 gtgaagaaaa aaataacatt tatataaagt taataaactc attaacatat aaagatatat
    25081 taccagggat aaatgagctt ataaaagaac ttaaaaaaaa taatgtgaaa ttgggaatag
    25141 catctgctag taagaatgca cctaggatat tagaatcttt gggaataaaa gatgaatttg
    25201 attgtatagt aaatccatct ttattaaaaa ggggaaaacc atatcctgat atttttattg
    25261 aagggagcaa gattctaaat ttaaaacaat atgattgtgt aggaatagaa gattcttatt
    25321 caggtattaa agctataaat gctgccaata tgacatcaat tggtgtgggg aaaaaagaag
    25381 tactaggaaa atgtgaccat attgtagaag atactagctt attaaattac aatacactat
    25441 tacaagcttg gagtaaaaag attaatttgg cttaaaacta tattaaaaat tattttaaaa
    25501 gagaggataa ggtatgaaga ataaatatga agatgtagct caattgataa ttgatggact
    25561 tggaggaaaa gataatataa ttgacttaac tcattgtatg acgcgattaa ggttcatctt
    25621 aaaagatgaa aagaaagtca atgcagataa attaaaatct atagataagg tagttggagt
    25681 aaactcaact tcaactcaat atcaggtcat aataggtaat gaggtaggtg ttgtatttaa
    25741 tgcaataata aataagggga taaataccac aggagatatt aaaagcgata taaaaaataa
    25801 aaataaaaaa aatagtattt taaataatat aatagataca ataactggtt gtatgacacc
    25861 tatgatacca gcccttacag catctgggat gataaaagtt atattatctc tttgcaccac
    25921 ttttaattgg ctatcatcaa attcaagtac atatagagta ttagatataa taggagatgt
    25981 agcattttac tttatgccta taatacttgc aataaatgca gctaaaaaat ttaatgttaa
    26041 tacgtcaata gcagttatag tagtaggtgt gtttttacat ccaaatttct ctgcatgggt
    26101 atcaagtggg gaccctatat catttatagg agtaccaatt caaggtgtta tatatgcagc
    26161 atctgttatc cctgcacttt taacagtatg gatgatgtca tatatagaaa aattcattga
    26221 taaattaaca cctagcatgt taaaaacaat tttaaatcca actttagtat tattaataag
    26281 tgcgccaata gcattaatag taattggacc aataggaaat ttcttaggag agggattagc
    26341 tagtataata aatttactac aaggaaggtt aggatttata atggtttgtt tattagcagc
    26401 tgcaatgcca tttatcgtta tgacagggat gcatcatgca ttgactccta tattcatatc
    26461 agcatttgca actacaggac aagaatcgct aatattaata tctcaagttt gtgctaattt
    26521 agcgcaaggt ggcgcgacat tagctgtagc attaagaagc aaagatagta agatgaaaca
    26581 gttagcatca gctgcatgga tatcagctat catgggtata actgaaccag ctctttatgg
    26641 agttacattg aaacttaaaa aacctgctat gttagcatct ataggagcag gaatcgcagg
    26701 gttatttgca ggaattactc atgtgacttt atatgttcca caaaatagta taatggcagt
    26761 acttggatta tcaggggaaa aggggatttc aaatatagta aatggactta tagttatatt
    26821 tatagcattg gttgctccat ttattatgac atatgttttt ggagttgaaa aaaatgttaa
    26881 ggaaggtata gataagtaat gaaatgtatt aggtagtatg aatagtaaaa gtgattaacc
    26941 tataaatttg attaaataat agttatacaa tgagtaagat aagttcaatt taaaacttta
    27001 aaaaaataaa tgatgaaata ctagtcttta ttgactggta ttttttactt taatgaataa
    27061 attcatcaat tatgctctaa ctactaaaaa agaggcgttt tgagggtata ttcataagaa
    27121 atattggata tttataatat tctattgtaa cttgtttgaa taagttatat atttataaca
    27181 taaggtatta taaatatata actttaaatg catataaaat taaataaata ctagaataat
    27241 tattatattt ttatgaaagt tttagatatt tttataaaag ttagtaaaat agagatacta
    27301 atgtatatac ttctaataca taataaaact ttatagtctt ataatgatgc aatacttata
    27361 attaacaata catactaaat gtgagatact tatagatgta cattatgtat aggaaagtta
    27421 tggtatatct acatacaata taatattata tttagttttt aatgacaaaa taatattaaa
    27481 gattgagaag tattttaaag tatatgaaat aaaataagta aatcaaatca acatataagt
    27541 ttttaattga ataattattt gaaaaataaa gttgtacgta gtagtatatt gatatagagt
    27601 attaaattag ttatcaatat aagataaaaa agtaaagttt aattgctcta aacattgaca
    27661 taaatatatt aaattttagt aaagaatttc aatgaataat agtattgcta tatatttaaa
    27721 cttaagttaa taagggtaga acaaaatatc tctaggaatt aatatatttc aaattctaga
    27781 aaagaaaata taaaaatata caaaaactaa ggatgtgaag taatggctaa taagattgat
    27841 aacgttaaaa ttactgatat atatattgat aataatagac tttggaaaat atatgatagg
    27901 gatttaaaac cgctattaga gtcaattaag gaagaaggtt taatatctcc aatagctgtt
    27961 caagaaagaa gtggtaaata taagttaata gcaggagaac atagacttac tgcttgtaaa
    28021 cagttgggat gggagacaat accagcacaa ataatagaaa gagagtatga agataatgaa
    28081 atagaaaatg caagacttac catattagaa gcagatgaaa atttaaaaag aaagtaccca
    28141 gattttatag ctgaagctca tatattaact aaaagaaaag aagcctatga taaaatagtt
    28201 gagtataaaa caggtggatt gacacctgaa gaatataaaa aaaaaatagg aggtaaagtt
    28261 acatcactgt taaatagtag aacaccatta acagatagtg aattaaaaga acttgatttt
    28321 cttgaaaaag atttagttaa tgtaaaaaca tttgcacaga atacgattga cagtactggc
    28381 ggaagtgaaa gtaatataaa ctcaaaatta aaaattgcaa aaataatacc gaatgagaag
    28441 gctaaggaaa taaaggcaaa taatataagt tcaaaaacac taacatctat agtagtaggt
    28501 gtaaatgaag aagagattaa gaaagcgtct gaaatacatc ttgatacaat aaaaagtata
    28561 aaaattcctg aagattctaa tataaatact ttatatcaaa aggctataaa gaaaaccaaa
    28621 tatgagttaa aagataagta ttttcaaaga aacaatccag ttgagtttgc tgaaagagta
    28681 tctgagaaaa tacatgaagt aatagatatt gaagaaaaga aaaaagagaa taaaatagtt
    28741 caattaactc aaaatgattt ggagtatata aatacagcac tagcattgct aaaaaatgca
    28801 gaaaagctgt ctataattgt agatgataga attgtgttta caaaatatat taaataattt
    28861 attatttagg agagaatatg aaaactacaa taagaaaaga aaaagaaata aaaataaaag
    28921 aaatttatgt agcacaaaga tttaaagatg aagaagataa agctaactta gataatttaa
    28981 ttgaaaatct aaaatttcat ggaatgataa atgccatcaa tgtgtgggaa gaccacaatg
    29041 gaaattacca tttaataagt ggatatcata gattaacagc atgcaaaata ttaggtaaag
    29101 aaacaatacg tgtaactatt gatactacaa aatataaaaa tgaagtagat gcttatagga
    29161 atcatagaca agaaaacctt catgaaaatg gaataagaaa acatcataca atataccaat
    29221 tatctaaaat atttgatgag cttcaagtgt tatatgaaca aataaaccca gataacaaat
    29281 ttgcagagga agaatattta agggcaagaa aaagagaaaa gatggcaaaa gaatctttaa
    29341 aaggtaggaa agcaaaagaa gaacaagaat atttcaaaag agaaatcgaa aaagctaagc
    29401 aaatacaaga aaaaactaag tcacctctgc aaaggttaat tgatgataga gggttttcag
    29461 aggtaaaggc taagcaaata caatttataa atggtttaga caaaataatg cctaatttct
    29521 ctaaaaaaat ggaagcttct aatatatctg agaatagaat atggaattta agaaaaatgt
    29581 ttaaaaaaga agatgtaata gatcaattta aaaaaattaa tactacaaga gatatgaata
    29641 attgggttag taaattagag ggaaaaaagg aaggttctaa aataaatgta tcagaaatag
    29701 cagatgaagg aaatggtatt gttagactag gaacaaaaca ttatgtatgc tactctgata
    29761 cagaacattt ggtaagaaag tttaacttta acataagaat ggttgtagat gataatgatg
    29821 tagctaaagc tgcaatagag gtattaggaa taaatcatgt gaaagcacta attgtttgta
    29881 caaatgatac agctcatgag ttggtattaa atgcaataaa gaaataatat ttagtttatt
    29941 tagaacagta tatttgaact ataactgtta gggcagaaaa aatacatatt ttgtgaatta
    30001 aaggactgta gataggtttg tttttggaca aatacatttg cagtttttta atatattaaa
    30061 atggctaagt tttaagtaat atttattttt aaaaatttaa tatactaagg ataaaaaata
    30121 caaaaaaata aaaataaata catagatact ataaatataa tgtaagatta aataagaaaa
    30181 atattatcta agttttagaa tttatattag acaaaaaatt taaataaaca atagaacgtt
    30241 tagagcagtt acctattttg gcgagatata tctttataaa aaataagtta tttattaagt
    30301 atataaatta aatacaaaaa agaaattaaa taatttaatt actttataaa gagagtgtag
    30361 agtttaattt ctttacagtt tctatttttt attttcaata aaatgagtgt aaatatctat
    30421 agttgtatta atattagaat gtaaaagcaa atgttgaaat attttaagaa tagtatcagt
    30481 tttaaataat ctagtaagat atgtatgatt tgatttagat tactgaactt gattgattca
    30541 atatattatt tgagtaattc ttcaagattt aaattgcatt gatattaata taatttattc
    30601 agtataaggt tgacatttat acataatatt aatataattc aattaagtac agataagtaa
    30661 atggagatga gtagatggaa ttgacaaaaa atgaaattga aattatggaa gtattatgga
    30721 gtgagcaacg tccacttaca agaacagaaa tagtgaactt atcggttgat aaatcatgga
    30781 aagatagttc aatacatatt ttacttaaca gcttattgaa aaaaaatgct attcgtgagg
    30841 ctggatatgt tcgaactggt aaaggatttg gcagaacgtt tgaacctacc aaatcaggag
    30901 aacgttatta tgcaggtata ttagcaaaaa ttgcgagaaa aacaagtata tctatgcttt
    30961 tttctaaact tattgaatca gaggatatta cagatgaaac tattgaagaa cttgaagaat
    31021 tattgaagaa aaaaagagaa tagactaaat gttaatatct ggagttagta tatattcatt
    31081 tatgagtgca cttgtatttt ctagttttgg attgttatta attgcagtat taagaaatcg
    31141 taattctttc ttaataaaga atagaacatc attactatta ctgttattag tactttcaat
    31201 agttcggcta ttgcttcctc tagacttata taatacattg cttatagaat ctgatacatt
    31261 tcttccatgg atacagacag tattggagaa gactatattt aatgatgtaa cttttggaga
    31321 attgatagtg attatatgga ttgtagtagc tattatattt tttgtgatat caatgttatc
    31381 ttatatagca gagcatagaa aaataaaaat agactttaca ataaaggatg aacaggtaga
    31441 gaaaatagcg aaagaagagt ttgcaaaaaa ttctgttatt aaagtatctc gaaatattga
    31501 tactcctagg gttacaggta ttttaaaagc atatgtatat ctaccacctt tatctttagg
    31561 agataataaa ttaagatata taattcaaca tgaaatacaa catgtaaagg ggaaagatat
    31621 attaattaaa cttttctaca ctctactaag atctatactt tggtggaatc cagttatcca
    31681 tatttttaat agtgaagttg acagtttact agaactaagg tgtgatttag cagttacaaa
    31741 acatatggat tatgatggaa gaatggtata tttacaaact attttaaatg ttttaaagca
    31801 aactaaaaat aaaagagaaa aatttagatt accatctttt tgcaaaaaca aaaatactca
    31861 gctaataaaa caaagatttg aagttgttct taatgaagaa tctcaaaaag atattaagga
    31921 aaaattaatt actatatgtt tagcattgct tttattcata ttttcatatt tcataatatt
    31981 acaaccagtt tcttatccac ctcaagagga gcttgtttca gaagttgcaa ttactaatga
    32041 aaatgcatat ttattaatac ggaaagatgg aagtatagat ctttttgtta atggagagtt
    32101 ctttggaaaa gtaacaaatg atgacttgga agcacagcca atttcagata taaagaatat
    32161 tagaaaagaa aattaaggag gttataatat gaaaagtact atgaaaaaag gcatttttgg
    32221 attactactg gtaattatgt gtgtagctgg aacagatatg gtttatgcta gtgaagtagg
    32281 tattgccatt aaaacagatt cttataagtc tgtagataca aaagcagaac agcttaaatg
    32341 gtattataga atccataatg gtaaaaagca aaaacgtctt tggtcaatta catatggata
    32401 ttggaaaact aattggatta acgtgtaaat gatttataga atgtattgat tttaaaatta
    32461 tgtaaaaaga gattaacata taataaatac caataagggt ttttatgtaa aaataagtgt
    32521 aattgttaga gcagagtgcc taaacattta cacttatttt taatttgtat ttattagtaa
    32581 aatttaaagt tattttagaa attcaaagta agaatttagt gaaaataatt aaatataata
    32641 aaaattatgg aattatattg acataaatgc attggtatta tagaattaca ttaacgcata
    32701 ataatacaaa tttatgtaag aataaagtat gtttactatg aatcatcaat aaattttata
    32761 aggttttatg catttggact attttagttt ttatttaagc tgttactttt aaatgatcaa
    32821 ttgtagcaaa attatcgata atagacaata atataaaaaa tgatttaaat caatctgtta
    32881 aatttaacga ataatattat taataattta aaatatcgta aaaaataatt aagtagtgtt
    32941 atcctaggaa tgagtttaac agaaatcata tgataatcta aagaattagg agaaaattgt
    33001 atgtctaaaa attatttaat gggatgtgga aatgagcaat ggaaggaagg aaaggcatat
    33061 gaagttacat ttattgtaac tgaagattgt aatttacgtt gtagttattg ctatgaagtt
    33121 cataaaaata ataaaaaacg tatgtcattt gagatagcaa aaaaaagtgt cgattatata
    33181 ttggataatg aggaattgta tgatgctcca gctgtaatat gggattttat tggtggagaa
    33241 cctcttctag agattgagtt aattgataaa attagtgact atattaagat tcaatcttat
    33301 cgaaagaaac ataagtggtt aaacgattat agatttaata ttggaactaa tggtactctt
    33361 tataatcaac ccctggttag taaatatatt aggaaaaata aagataaact ttctataagt
    33421 atgactattg atggaactga gagaaaacat aatttacata gaatatatga agacggtaga
    33481 ggttcataca atgatgtatt caaaaacata cccaaatggt tatcagatat gccagactca
    33541 actacaaaag taacctttgg aagtgaagat ttgatatatt tgaaagaaag tataattcac
    33601 ttatggaatt caggtttaaa agatgtgcca gctaatgtag tttatgaaga tgtatggaaa
    33661 gatggagatg ataaagtatt tgaaaatcaa ttaatatctt tagcagatta tgtaatagat
    33721 aataaacttt ggaatgaggt gaattgcaca ttatttgatg aaaatttagg tggtccaata
    33781 actgatttta atctaaaatc taatttttgt ggaactggaa ggatgttagc tattgatgct
    33841 aatggagatt tttatccttg cttaagattt tctgattttt cattaaatga caaatgtggt
    33901 agatcaatag gaaatgttaa tgaaggaatt atattagata aagttagacc atttttagcc
    33961 ctatcaactg agaatataag caaagaagag tgtataaaat gtgaagtggc atcaggatgt
    34021 gcttggtgcc aaggttctaa ttatgattgt gcagataatt catcaattta taatagagct
    34081 acatacatat gtaagatgca taaggcaaga attagaggaa ataactatta ctgggatagg
    34141 ttaaaaagag aacataatat tcgcagaaag attgaaccaa agttcaagaa aaatatgtat
    34201 tttatacttt ctgatgactc tgtagaacat tgtagctact ctagtaaatc aaattcagaa
    34261 aatattatga gcaaagaatt gttaaaaaag gcattgaatt actgtgaaaa gaattttttc
    34321 aaaccaatta ttttgaattc aaaaacccaa gagaatatta ttgacttaga tagtttttcg
    34381 gtattatcaa gaattgaaat aagggattta aaaatcaagc caacatataa aaatacaaat
    34441 gaaattgtat gtttaaatat agaggatatt gatgaatata ttggtggaag gaattgcatt
    34501 cttaatattt attcttccca aattaatcaa atatatatta gcattaaaaa attattggaa
    34561 aagtcaaaaa gaattaactt agttttcaaa ggtaatatta atgagatcga cttaaaacta
    34621 tatgaaggtg aactttttaa aattaaagat ttattaatca agctttatga gcgaaagcaa
    34681 tataaagagg ttaatgttat tacagataga atatttttga ataaaatgga caattgtgaa
    34741 tgtggagaga ataattatgc tattgctcca aatgggaata tttatatttg cccagcattt
    34801 tattttaata atccagaaga ttttataggt aatatagatg aaggaataac agaagataaa
    34861 ttatttaatt gtgatatgga tcactctcct gtctgcttag cttgtgatgc atatcagtgc
    34921 aatagatgtg tatatcataa tataaactgt actggagagt acaatatacc tggacataag
    34981 cagtgcgaaa aaagccacat tgaaagaaat acctctatga tactacaaag acttataaaa
    35041 gattataaat tacctataga tttagaggaa gatattaaac cattagatta ttctgatcca
    35101 attgaactta ttcttggaga attagatgtt aatccatatg caagcataaa ataaaaactt
    35161 agggggatat agaaaatgaa tttaataaca actatttcta aagaagataa cgaaacttta
    35221 ataaatatag ttgaagaaat taatacttta aggaatctta tgattacatt gactgaagaa
    35281 aataatcttt ataaagagaa cagtgattta tataaacaga taactgaaga tatcaaagaa
    35341 gcaaatcata aatatacttt atattgggaa atgttaatca aaaagtacaa tcttaattta
    35401 gaattagcta ataaatatac tcttaatttc tctgattgta gtatctattt aaatgagttt
    35461 gatgaagatc aaatgttttc tgatgaaggt tataaatgtg aaaatatata gataatatgg
    35521 agtatattaa acaaatataa aaagagagag ggggatatta tatgaaatta gattcaaaga
    35581 atattgaaac ttcagttgac ccaagatggt gtccatgtaa aaatggaggt tgtcagtttt
    35641 cttgcatgaa aaaatgtaca ggatgcttgg gttcatgtga aggaggttgt aaaggaaaag
    35701 tacttattca accataattg tttattttaa taaaacttgt ataaagggga gtgttaaaat
    35761 atgaagcttg atagtaaact agttaatgat aacataaatc caagatggtg tccatgtaag
    35821 ggtaattgtg ttgcgagttg taaaggaact tgtatactag gttgtcacgg atgtgtaggc
    35881 actagataaa aacaaaacat gtttataacc ttatgcattc taattttaat atacttttaa
    35941 atttagcaat gtgtctaata aaattatagt acttaaaaag ctccatgttt tatgaagatt
    36001 catagcatgg agtttttcaa agttataaaa atgttactta gaggtgaaaa tatatggtct
    36061 ctgaaattaa gaaaattaaa aattataaaa tatttataaa atacataaag ccttataagt
    36121 taagatttat atttttatat ttagctacaa tattaagtaa tgtagcagat ctttttccta
    36181 tttattttct aggtaagatt ataaattatg taacagaagg aaagtttgat ggcattgtca
    36241 aaataatttg ttttctattt attattttta tgataaattc tttctttagt attattgaaa
    36301 cttatttaac taagtggtta atatttagaa tcaatcaaga tataaaagct gatatttata
    36361 aaaagagcat agagttatct ataattgatt tcaatacatt aggatcagga catattatat
    36421 cactaattga aggagatagt gaaaccatat ctaacttttt tgtggttaaa atagtagaag
    36481 tagttattgc aattattaag tctattgttt cattattttt tctactttat ttgtcaatac
    36541 cattaacaat aatagcaata atatcatttc caataggatt tttgggttat gtaatatgtg
    36601 gaaagaaaat aaacataaaa actagtttat taagacagct aggtgatgaa ttgtattcat
    36661 ttcttaataa ttctttagat ggaattaaag atgtgaaagc ttacacaatg gagcaaatta
    36721 tgtacaaaaa atttaaaaat tatataaaac gttataggga attaaatatg gaaattgcag
    36781 ttttagatat tattgtaggt tttttaaatt tatttatttc ttcattaaca gaatggatta
    36841 ttataggtta tgggacttgg ctaataatat ataataaatt tactataggt tcgtatgtag
    36901 cttttaatgg ttttttagca acattttttg atggaatcaa aagtatatta aatattaact
    36961 tagtttatca aaccgttatt gcctcaatag atagaatttc taacttcttt gatatttcta
    37021 tagatcatag taatagatct ttgatgatta gcaaaattaa tggaagaata ttatttgata
    37081 aagtgcattt tacttatccg aatacgaata aaaaaatatt aagtgatttt acagctactt
    37141 ttgaaccaaa atcattatca gttattgtgg gattaaatgg agcaggaaaa agtaccttgt
    37201 tttcattgat tgaacaattt tatttgccta acaatggtaa tatatatatt gataacaata
    37261 acattcgaaa tattgactta gataacttaa ggaagaatat ttcaatagtg catcaaagac
    37321 ctgtcatgat taacggtact ataaaggaaa atttattata tggagatatt aatgctacga
    37381 tagagaaaat aaatcaagtt tgtgaaaaag tagatttagc aaaatttatt gaagaactac
    37441 ctgatagatt tgatacaatt ttggaggaat tatcaggtgg acaaatgaaa agaatagcta
    37501 ttgctcgagc attaataaaa gatcctaaga tattattaat ggatgaaata acttctgatt
    37561 tagatggaaa aaatgaaaat gaaattatgt gtcttttaga tgagttatca aaggagaaga
    37621 caatcataat aatttctcat agaattactt ctataaccaa tgtacccaat atttatgttt
    37681 tagataatgg tcacattgtt gatagcgggg accatgaatc tttattaaag agatgtccta
    37741 tatactctgt tttaattaat aatcaatctt aaaagttttg tatgaaagga aataatggta
    37801 tgaaaaaaat gataattgaa gtttcaaact tatctaaagt tgtagacttg ttaaacacag
    37861 aacttactat actaaggaat atagatttat acatagaaga aggagaattt gtttctataa
    37921 tgggtgctag tggtagtggg aaaagctctc taataagtat attaagtggt cttgataaaa
    37981 actatactgg aaacgtgaaa gtttgtggtg agaatttatc ggaattaact gatgatgaac
    38041 ttgctgaata tagaaataga aagataggga ttgtatttca atcatttaac ttaattacat
    38101 caatgtctgt tgaagaaaat ataaaattgc cattgatttt ttctgataat aaagagtata
    38161 aaatagtaga taagatgatt aaaaaggttg ggttgacatc aaaaacaaaa aataatatta
    38221 aacaattatc aggtggtgag aagcaaagag ttgctatttc aagagctcta gtttgttctc
    38281 caaatatact ctttgctgat gaaccaactg gatcattaga tagtactaat agtcatgcta
    38341 taatgaaatt gtttaagaat ataaacaatg aatatggtac tacaatagta atggttactc
    38401 atgatattca aatggcagaa tatagtgata ggattataag tattaaagat ggaactatta
    38461 taaaataggt ggtgatacat tgatatttca tgaagtttat aaaatatata gtaagaatag
    38521 tttgaagaat aataaattat taaaaatctc ttgtataata tctattgtat ttgccacagc
    38581 aatattactt tttacaagag tgttaacgga tacatattca agtgaagtta agagaaatat
    38641 ggctataaca aatggtggag atataaaaat acaaaatata gaatataata aatactactt
    38701 tacaagtgaa caaatagata agttagaaga attaaaagat aaagaatcta ttgattttca
    38761 gttgggaagt agtatgaata caaatatatt gtcaaatggt atgattgaaa gtactgaatt
    38821 gactgtagta aataatataa aaatgcaaaa tacatattta aaattaagaa atgaaaatga
    38881 tatagtttta tcccaaaaaa cagctaataa attaaatgta aatataggag ataaagtgtt
    38941 tttaaaacta cattcttcag tttatgatga tacatatttt aaagttagtg atataatacc
    39001 aaaaaagttt tcattaagta cagctcaaaa agaagcagag gttggccaag aggtagttgg
    39061 agaaagttat gtatatttgc ctaatgaaac taaatataat gtagcttata taaatataat
    39121 aaacaaagaa aatgtgaaaa atattaaaaa tgaaataaaa aatgtattta aaaaccattt
    39181 tgaagttaga acaactgatg aactagaaca gtcaataata aagagaatat ctatgcaatt
    39241 agattcaata aatttaattg gagctatttc attattaatc actggaattt gtctatgttc
    39301 tacatttatt gtatttattt taaatcgaat acatgatttt tcaactttta aggctttagg
    39361 aattaaaaaa agaagtttat cttttctagt atttactgaa cttatgtcaa ttactataaa
    39421 ggggattata ataggtatta ttttggggat tcctataact atattctata ttaacttaca
    39481 acatattaat ctatttaata tttctatttt gagtattatc aaaaatattt tcatttcaat
    39541 agttattata ataattgaaa catcaatatt ctcattaatt cctataagtt ttgttaaaaa
    39601 aataccttat gaaggaataa atagagataa tagtatgttg tcttcatata aatttaactt
    39661 tattccagat ataattcttg taatattttt aacaagtatt tcttttacaa tatatgtgaa
    39721 gtcctttcta ggtatttttt ttattttagg attaatacta ctagatttat tggtatacag
    39781 tttgatatat gcattattaa aaatggtatg tttaattaaa aaaattatta agggaaaata
    39841 ctcgattact tttatatatc ttaataatga ttgtaaaacc aatgctttta gctctagtct
    39901 attaacaata acaataatat ttgttttgtt gttgtttatg atatctgaaa taacctttgc
    39961 tatgtttagc aattatgaag ttgataatag tataaaaaat tcaattgtat atcaaacaac
    40021 tttagaagga aaattaatta cagataaaaa acttatcgaa aatgatatag attattttca
    40081 atattatcca attaaaatag atagtataga gtcagtaaat aatatttctg ttaatgatta
    40141 tattgaaaaa attccatatg agaatagaaa agatgtaatg aatgatttaa atgacttaag
    40201 tgttgattta ttcaatacta aacagacaat attaaaaagt gatttagagt atggaaactg
    40261 gttcaaagaa aatgataaag aaaatagtat aattataaat aattatcttc atagatactt
    40321 aatagattat aaactaggcg atactataaa gttaagaatt aatggaaagg atatagactt
    40381 taaagtaata ggatttttaa gtccaaaatc attgaacaaa ggtgtagatt taggatatat
    40441 aaatataaat gaaaatattt cacctaaaac ccttgattta tctaaaaatc aaccagtaat
    40501 atattttttt aaagaaaagt tagataacac tttacttagt aaattattac ataatgataa
    40561 atatgctaat ttagaggatt ataatgattt tgcttattct atgaaaacat atgttgatga
    40621 tcaaaagtca ttacttttga atattatatt tgctgtgtca ttgtcaagta tacttctaat
    40681 actaacatct caaataatta tttttataag gagagtacta gattatcaaa ttatgtatag
    40741 agtaggaatg agtaaacgaa aattgataaa aataggttta ttagaaatga taattgtatc
    40801 aattatccaa agtattctta tagcaatttt ttatgaacta tttagattct tactaatttc
    40861 attgttacag agagattata atattaatta tttattgatt ttaatagaat ttttagtagt
    40921 attgtctata aattgtttta tatttatatt ggctcaaaga aatattaaat tagacttata
    40981 aattttttat tgagacaaat ctagtataga ttttaagtca aatgaagagg ttaataattg
    41041 aatttataaa tcgaaaaacg acctattgtg agagcttaaa ttactataga aggtcgtttt
    41101 ttattacaga aataaataag agatagagaa tagtttagag attagaaaga aaatataatt
    41161 taaaacatat aacaacatat aatcttctaa taaataaagg atttaatgtt gttgatttta
    41221 aaaattataa taaaactatt aaaaatggac tctattaaat taatattaat aagaataatt
    41281 attagaactg acaaaaagca acataaaaga ttgatgaagt atatggaaat aaaaagttga
    41341 caaaatatgt ctgatgtttt atcatattaa ttggaattag gtagtaattg tttaagtaca
    41401 agctaagctt attcattaat aatagcagta tcctaggaag gagtatgccc attattatgg
    41461 ataagctttt tttatgctta aaaggaggat aatcatgata attaataaga tattaaacaa
    41521 taatgttgta atcacattag atgataatga tgaagaagtt atcgttatgg gtaaaggaat
    41581 tggttatcaa aaatcaaaag gcaatctaat agataaaact aaagtaaata aagtatttag
    41641 aatatcaaat aaagaaatat caaacaaact acaagaatta ctcaataata ttcctataga
    41701 acacatgaaa ttatcaagtg aaattataga atacgcacaa ataaagttaa acaagaagct
    41761 aaatgaaagt atttacatat ccttaagtga ccatacatat tctgcaattc aaagaatgaa
    41821 agaaggaata aatgtaaaaa atgcaatcct ttgggaaatt aaaagatttt ataaagaaga
    41881 gtttgaaatt ggaatgaaag cactagatat tattgaaaac aaaacaggta taaaattacc
    41941 agaagatgag gctggattta tagcctttca tatagtgaat gctcagttaa gtgaaggtca
    42001 tactttggca tctgatatta cgaagttaat acaagaagta cttagcatag ttaggtatca
    42061 ttttaggata gaatttcatg aagaatcagt gttttattat agatttataa tgcatttaaa
    42121 gttttttgcg caaagattgc ttttagatag tgcacatgaa ggtgagacag acaaagaatt
    42181 actaagcatt attaaatcta aatataataa agagtttgaa tgtgtagtta aaattaaaaa
    42241 tttcattaaa aaacaatata actacatatt aacagatgat gagcttatat atttaacaat
    42301 acatttagct aaagtagtta aagactcaaa tatgtaagtg aaataatttt tcagtagtat
    42361 attaagaatg attgaaagga gtgatactaa caaaattata cctatggttg gatggtaaca
    42421 ttgagttggc caaaccttca aatttcaaaa aattaattta aacgaaatat ggaggagaaa
    42481 aatgggaaaa tacaaacaat tagcacaaga gatagtaaac aatgttggtg gaaaagaaaa
    42541 tattagtggg ttagtacact gtattacaag attacgtttt actttaaaag atgaaagtat
    42601 agcaaatgac aatgtattaa aaaacatgga aggtattgtt actgtaatga aaagtggagg
    42661 acaatatcaa gtagttatag gaaatcatgt tgaagctgtc tataaagatg tagttgaaat
    42721 aattggttta gatgattcaa gtacaagttc agaaactaaa aaatcaggta atatactaga
    42781 taaaggtata gatataatat caggaatttt tcagccagtg ttaggaataa tggcagcttg
    42841 tggtatgttg aaaggattta atgcattatt tgtagcaatg ggattatata gtgatgtatc
    42901 tggtggttat atggtaataa atgcagcagg agatgcatta tttacattcc ttcctttgtt
    42961 cttaggatat acttcagcta agaagtttgg attaaaacca atgttgggat tagcactagg
    43021 agctgcagta tgttatcctg ctatacaagg tagcagtata tcagcaggag cagatgtgat
    43081 gtacacttta tttaaaggaa caatgtttgc atcaccagta tatattgatt tctttggact
    43141 accaattgta tcaattgatt atactggaac agtcgtacca attatattta tagtgtattt
    43201 tgcttctagg tgtgaaaaat tatttaataa gtgtgttcca gatttagtta agtttttctt
    43261 tgtgccaatg cttacattat taataacagt gcctgttgca cttatagtta taggccctat
    43321 agcaacattt ggttctacac ttatttcaca aattgtaatt tcaataagag attttagtcc
    43381 actattggca ggtgctatag taggatttac ttggcaaatt cttgttattt ttggtatgca
    43441 ctggggattt attcctgtat atataaacaa tgttatgact ttaggatatg ataatgttat
    43501 gatgccattc tttgcctgta catttgcaag ttcggcagtt gtattggcaa tatttttcaa
    43561 gactaaagat aaaaaactaa aagagatggc aataccaaac tttatatctg gtatatttgg
    43621 agttacagag ccagcaattt atggaatatt attgccttta aagaaaccat ttataataag
    43681 ttgtattgct agtggtattg gaggcgcttt ctatggattc tttaatctta gaaaatttat
    43741 aactggagga atgggaatat ttgaacttcc agcaatgatt gaaccagatg ggggaatggg
    43801 taacttaata gtagctcttt ctggtatagc tatatcaatg gtcgtagctt ttgtattaac
    43861 tatgatttta tataaagatg agaaagtaga agagtctaaa aaagtaagaa ataagggtaa
    43921 agaagaaata aaagaagtca agtctactaa attagaaaga gaaatagtaa caagtcctat
    43981 aaaaggtgaa gtattaaaat taagtgatat agaggatgca gcatttgcat ctggtgtact
    44041 aggtcaaggg gtggcaataa tacctagtga tggaaaagta gttgctccag tagatggggt
    44101 agttacaacc ttatttccta gtctacatgc tatagggatt ctttctgata caggtgttga
    44161 agtgcttatt catattggat taaatactat tcaattagag ggaagaggtt ttgaggcatg
    44221 tataaaacaa ggtgatagaa ttacaaaagg tcaaactata ttaaactttg atgttgatgc
    44281 aataaaagag ttggggtata gtactgtaac tccaattgtt attacaaatt catcacaatt
    44341 tttagatgta gtagaaacag aaagtaaaaa tattgaatta gaagacaatc taattacagt
    44401 cttattttag taaagattga ggtattagca taatctagtg ctttggttat aattttagga
    44461 ggctttgact atgagtttta agaatgattt tttatgggga ggagctactg cggccaatca
    44521 atgtgaaggt ggatacaatg aagacgaaag aggattggca aatgtagatg tatgcccaac
    44581 aggaaaagat agaacagcag ttattacagg gaaactaaaa atgtttgatt ttgatgatga
    44641 gcattattat ccagctaaaa ctggtattga tatgtatcat aattataaag aagatataaa
    44701 gttatttgct gaaatgggat ttaaagtata tagaatgagc attgcatgga gtcgaatatt
    44761 tccaaaaggt gatgaagaaa caccaaatga aaagggactt caattttatg aaaatatatt
    44821 taaggagtgt aaaaaatata aaatagagcc tttagtcact attacacact ttgattgtcc
    44881 aatgcattta gttaaaaagt atggtgcatg gcgtaatcga aaaatgatag gtttctatga
    44941 gaaattatgc aaagttatct ttagaagata tagaggatta gtgaagtact ggctaacttt
    45001 caatgaaata aatatgattt tacatgctcc atttatgggt gctggtattt gctttgaaga
    45061 aggtgaagat gttgaaaaga taaaatatca agctgctcat catgagcttg tagctagtgc
    45121 aattgcaact aaaatagcac atgaagttga ttcaaataac ttaattggat gtatgtttgc
    45181 agctggaagt gtatatcctt atagttgtaa tcctaatgat gtatgggaag ctacaaagtt
    45241 agatagagaa aattacttct ttgtggatgt acaatctaaa ggtaaatatc ctaactatgc
    45301 gttaaagtat atggagcaaa aaggtattac accagaaatg gaacctggtg atattgaatt
    45361 attgaataaa tatacagtag attttatttc attttcatat tacaatagcc gttgtgttag
    45421 aaccgatgaa aatgcagatg atatggctga aggaaacata tttacatctg ctaaaaatcc
    45481 atatctttca tacagtcaat ggggatggcc aattgaccca ttaggtttga gaattacact
    45541 aaatcatgta tatgatagat atgaaaagcc actatttatt gtagaaaatg gattaggtgc
    45601 taaagatata gctgatgaaa atggttatgt agaagatgat tacagaattg attatataag
    45661 agaacatata aaagctatgc atgatgcagt ttctatagat ggggtcgatt tattaggtta
    45721 tactacatgg gcacctattg atttagtaag tgctggtaca ggtgaaatgg aaaagcgtta
    45781 tggatttata tatgtagata gagacaatag tggtaatgga agtctaagaa gaatgaaaaa
    45841 gaaaagtttt gaatggtata agaaagtaat tgcttcaaat ggtgaagatt tatattagac
    45901 aagaaatcta tgttaaataa gaaatttgta ttaaataaga agagtataaa aattaataat
    45961 aagtataatt tttaactttt ttaactatag aaaatcaata cagaattatt ttacattgta
    46021 ttgatgcaat agtatgattc acaaataaaa ttttagaaaa taaaattgtt aagaagtatg
    46081 ggaagtaagt gcaatttact ttgtaataaa agatgaaaaa ggcgagctta tgttttaagc
    46141 ttgtcttttt tattatgtat aaactatgat attttaaaat tctatgaaaa atttatttaa
    46201 tagagaaatt aaaaatttaa tggtaatcaa attctttacc aatgaatata aaaaatgtct
    46261 acgtgttata atagtttaaa ctaataaacg aaaggtagat gaatgaatat gaaataccaa
    46321 catataatag aagttgacaa agaactttgc attggatgtg ggctttgtaa aaatgattgt
    46381 ccagtaaaca atataattat agaaaataaa aagtcagtaa ttaaaaaaca agattgtcta
    46441 atgtgtggac attgtgcagc aatatgtccc acaaaagcta ttaccttgac aggatttgat
    46501 gaacctccta tagaacttac aaataagcca aagctagatt cagatgaatt actaatggca
    46561 attaaatcta gaagaagtat acgtaaattt aaagacaaag aagtttcttc agaaattgta
    46621 aagcaaatta ttgaggcagg taggtatacc cctagtgcta aaaattcaca agatgtatca
    46681 tatattgttt tagacaataa aaagtcaatt tatgaaaacg aagcagtgaa attttttaga
    46741 aaaataaaac ctattgcaaa tatagctatt aaatattcaa aagaagttga gattgacaat
    46801 aactttttct ttaagcatgc tcctattgca ataatgataa ttacaaaaga taagattagt
    46861 ggttcacttg cagcatcaaa tatggcatta atggcagagt cttatggcct aggtgtttta
    46921 tttagtggat atttttcaga tgtagcaaat aattcgccaa aattaaaaaa gcttttaggt
    46981 ctaaaacgca gtaatcatgt tcttacaaca ttagtaattg gatacccaga tgttaaatat
    47041 agacgtactg cacagaaaga agtagcaact gttagatact tataagagag ggtggatttt
    47101 atggaaaaag aatgtcaaca aagaatgcaa gaaataacgt ctaaatttaa agaatgtcgc
    47161 aaagctatct ctgctatggg tgatgagact agacaattga ttttaattgc tcttttagag
    47221 agtgatttta atggtatacg agtgggagaa atcacaaaaa aaacacatct ttctcgtcct
    47281 gctgtatctc atcatcttaa gatattaaaa gaagcagaga ttgttaattt gcgtagagaa
    47341 ggaacgaaaa attattatta tcttgattca aaaaaatcac aatggaagtc actaacagag
    47401 ctaataaatc ttatatttgt tggaatacaa catattagtg aaaatgatat aagaaaaggt
    47461 gattaaatta tacttgattt aatacaaaaa gattgattta ggaactaaaa agttcacttt
    47521 gagacactat cttttgaact atacccatct taggagacag ttaaaatgta taaaactgta
    47581 taaaacaatg ggtatagttc attttataat ggtttaaata ttaagaatat attattctaa
    47641 atagtatctt tctctgtttt gagttttatt tttatactca atagcttcag tggggcaacc
    47701 acaaatacat gccatacaat gagtacagtt atttttccaa actggttttt tgttttttaa
    47761 attaatatta tttaaaggac atagctctac acattttcca cagccaatgc atttatcagt
    47821 ataatgaaat cctttggcac taataattgt cttataaaaa actgtattta ttataccact
    47881 tttaattgta cctcctaagc cactaggagt aatagtttca aattcatttt cattgcgtat
    47941 atcagaaata atcctatata tttgtttatc tgcttcttta atcatttgtt ttgatgtttc
    48001 tttgtctgtt gtagaaaata aagctatata attctctggc attttaattt ctgccatacc
    48061 ttttaattgc cattccttgt atttacatag tttttgaata tagtttatgg attttgctgt
    48121 atctccacca caagtcatta caaagtaaac tctgttgctt cctagaaatt ttgtttcttt
    48181 tataaaatcc gtaaccacta ttggcaatct ccatgcataa gtaggacata caaatatgaa
    48241 tggtttatct gttgatatta attcatctgt tttttcctct tttataagtt gatttagtga
    48301 tatcagttca tcatttaatt cttgtgcaat tttacgagcc acatatcggc tattaccagt
    48361 tccgctaaaa tataaaatca taataatatc tccctaacta ttttttattt taactcttaa
    48421 ttttttattt attatagtaa tttattgata tattctattc aaatgtatgt aaaatttagt
    48481 agttaagaaa attataacac attagtaatt tttatactta ttggtaaaga atttgattac
    48541 cattaaattt agcaacaaga catcaactgg atttttataa taagaaggga tagtaatttt
    48601 catgtgaaag attgtaaata taaaggtgat tttgaagggg aataagaaga taaaattgat
    48661 agcttaataa aaaatattta acttttatat taactgtttt aaatattata attatctatt
    48721 ttgaataatc aactatagaa gactgtatac aaagacaaag ttgtgtacag tcttttttat
    48781 aaatttaatg tctataatta aatacactat taaaatcaac aagttattat ttcaaagtag
    48841 tattatccaa atttttatga tggttaatac aatttgttag ccattttata gcaccttgtt
    48901 ccctgataat agctccatca agaactatat aatcaccaaa atcattacta tcaagaggag
    48961 gaacttcact ataacgctcc atttgactgt acaagaacgt aattctttct tggtgttgaa
    49021 gcaattgatg ctttagtaaa ataagcctag tatctatatc taaattatta gaaaaataca
    49081 ttctaagacg aaaaatatcc ttaggggttc tttccattgg ctcatccttt tcaagccatt
    49141 tcaagaactc atctttacct ttttctgtga ttgtgtataa ctttttctct aatacatcac
    49201 cactaatttt aatatcatat acaataagct tttcatttac caactttttt agttcaggat
    49261 atatttgact atgctttgca ttccaaaact cagctaattg aaaattgaac tcttttacga
    49321 tatcataacc agtcatagga tttctattta ataatcctaa aattgcatac tttaaagttc
    49381 gcataaatac acctctttct ttaattacat acttattata acacgatata tttagtttga
    49441 attaattaat atagctatgt tttaacaaga acttttaaat tatgagtaac aaaaaataaa
    49501 taaaactata tataaaaacg aaattatgta aatgcaaaca tgtaaaagtt tacatgtttg
    49561 catttacata tagaaaaaat tgtgataatc ttaactaaga aattctattt aataaattta
    49621 tcgaggagga gagtaatgaa tttaacacaa aaaagatgga ttatattaat tgcaagttgt
    49681 ttcatcaatt tatgtattgg ttcaatatat gcgtggagtg tatttgcatc acctatggca
    49741 gaatatttaa atagtcttgc tggaacaact tttacagctg ctagtttagc aattgtattt
    49801 acagttacaa actcagttgg acctattact atgattacag ggggaatgat aaatgataaa
    49861 tttggtccta aaaaggttgt atttgtagga ggattaattt ttggtatagg tatgatattg
    49921 gcaggttttt caaaaggatt gcctatgttg attttatcat atgggataat aacaggcctt
    49981 ggggttggca tggtttatgg atgtacaata agtaattcaa ttaaattttt tccagataaa
    50041 agtggattag ttggtggtat aacaacagca gcttatgggt ttagttcagt aataatgcct
    50101 ccagttacta attggataat taataaatat ggagtaactt ctgcatttaa atcaataggt
    50161 ttaatatttc ttataattgt atgtgtttct tctttcttta tcaaaaaatg tccagcagat
    50221 ttcacaccag aaggatggat accaccagag aaaaaaggaa aagtaagagt tgttattaat
    50281 aaaaattgga aagaaatgct ttcaacacct atattttatc taatgattat aatattaact
    50341 tgtggagctt tctatggatt aatgtgtgtg tcattagcat cttctctagc aacaaatatg
    50401 attgggatga caagttcaga tgcggcaata gtagtttcaa ttttagcctt gtttaataca
    50461 ttcggtcgta ttgttgcagg atatatatca gataaaattg gtagaataaa tactttatca
    50521 ggtgcattag ttatttcaat ttttggttta ttatgtttgt tattctcaaa agaaggagat
    50581 gtagcaacat tctatattgg aataataatt ataggtatat gttttggttc atttatggga
    50641 attttcccag gatttacagt agataaattt ggacctaaaa ataatagtgt aaattatgga
    50701 atcatgttta ttggatttgc ttttgcagga tatattggac ctgcagtgat gaaaaatgta
    50761 tattctgtag atggcaatta tcaaagggct ttcattatag ctataattat agctttaatg
    50821 ggttttatat taacattttt atataaatac ataaataaaa tacaaaattt aaaaatagaa
    50881 agtttaaaaa tagaaaataa ataaggggag gtataaaaga tggaaagaaa atatccaaat
    50941 ctatgtaagc caattaaaat tggaaatgta acattcaaaa atagaatgtt ttcagcacct
    51001 atggggggaa cagacataac agcagattgt acaattggct caaaatcaac agccttttac
    51061 gaattaagag caaaaggtgg agcgggtgca gttacaatta gtgaatgtat ggttcatcca
    51121 gaaacagatg gttcacatgc atatcattta gatttaaaaa tagttgactc cttagcaagc
    51181 tttacttata cagcagatgc aattcgccgt catggagcaa taccaagtgt agagctatct
    51241 cactcaggac aatattcagg aacttattta gttgataagg ataagaagag aggattatca
    51301 caatggggag taagtcctag tgttcgtcct gatggattaa agataaaaga acttacagaa
    51361 gaaataattg ctgaaatagt agagtcgtat ggaaatgttg cagcattgac taagagagca
    51421 gggtttgaga tgattatgat tcatggtgga catggatggt taatcaatca attcttatca
    51481 ccttacttta ataaaagaac tgacaaatat ggtggttctt tagaaaacag agttcgtttt
    51541 gctaaagaag tcttagatag tgttcgtaaa gcagtaggtc caggatttcc aatagagttt
    51601 agaatgagtg gttctgaatt atttgaggga gggtataatt tagattatgg aatagaaatt
    51661 gctaaattat tggaatcaag agtagattta cttcatgtat cagcaggtac ataccaaaga
    51721 gggtttgcag taacacatcc ttctatgttc ttagagcatg gatgtaatgt atatcttgca
    51781 gaagaaatta aaaaacatgt aaacattcca gttgctacta taggagcatt aaatgaccca
    51841 gaaatgatgg aagagataat tgctagtgga aaagcagatg ttatttacat ggctcgtgca
    51901 ttactagctg atcatgaatt accaagaaaa gttatgagta atcaagatga aaaaatagtg
    51961 aaatgcctaa gatgtttcac ttgtatggca gaacgtgcta ccacttctac aagacgttgc
    52021 actgttaatc cacttattgg acgtgaacta gatggaactg aagttgttcc agtattaaaa
    52081 cctaaaaaag tattaatagc aggtggtgga ccaggaggat tgcaagcagc cattacagct
    52141 gtaaagcgtg ggcataaagt aatactttgt gaaaagacta atgaattagg tggaatttta
    52201 aagggagaac aagcacttcc atttaagtat gaaatgtatg aattaggaaa tacttttgga
    52261 aaaatagcaa aagatttagg tgttgaagta cgtttaaata caacagttac aaaagaatat
    52321 gttgataatg aaaatgttga tgcattaatt atagcagtag gttctgaacc tcttgttcca
    52381 ccaatagagg gtcttgatgg agaaaatgta gtaatagtta atgattatta cctagaaaaa
    52441 gaaaaagtca ctgacgaagt agtagtttta ggtggaggat tagcaggatg tgaggctgca
    52501 attcatttgg ctcaagaagg gaagactgtt cacttggtag agatgagagc agaacttgcc
    52561 ccggatgcaa atataaggca tcgtccaata ttattagaag aaatagagag acaaggtata
    52621 tatgtatata cagaacataa aggtttaagt gtaacagcag aaggtgtagt atgtatgaat
    52681 aaatctggga ataaaataaa tattccagga acttcagtaa tatgtgcact tggacaaaaa
    52741 ccaagaagag aagtggtaga tactttactt gattgtgctc catatgttgc tcaaattgga
    52801 gattgtgttc gtgcatctac aataacaaat gcagtatacc aaggtcatca tgctgcgcta
    52861 gatatatagt taaaatgaag tagatagtat tgttttatta taaaaaagga gtgtctcaaa
    52921 atgaactttt tagttcctga gacacttttt tgcatgaaat caaatatatt tttatcattt
    52981 caacaatgaa aaaaataaat atatatatga atgttaagat tagttgatag aatttaaata
    53041 ataaatccaa tattataaac ataggaggta tgaaaaatat gattaatgag aatttaaaaa
    53101 gtctaagaaa aatccaccag tatacataag aagaattagc tgaaaaactt aatgtttcta
    53161 gacaatcaat atccaaatgg gaaagtagag tttcccatag ctaagaattg aaataaataa
    53221 acaaatccat aaatacctac ttgtgctata ccgataaaaa gatgatttta ggaactatga
    53281 gaagtataaa ataacagtgt ttatcattat attatagtgt tcctttctgg cttgtttgtc
    53341 cgacatcttc tatagcagga tttgtcaaga gcttgttgca taagcaatgc ttaaaatctt
    53401 gataaaatcg tggaatgtaa aacattatgt attgtagagc ttaaaaggaa agacaatgta
    53461 atatggtaat gttatatgat atattaaaag aaagaaaaat ttgtatttat ataggagatg
    53521 tacatatgag attatttgga aagttaaaag gagttaaagc aaaaaatttg tgtcctcaat
    53581 ttcgttatca accatttatt tatgaaaatg ggtgtgttga atgggggaag gatatctgtc
    53641 aatgttgtgg aaaaaaagta aacaaatata ttaatatgat atattcagaa caagaagtag
    53701 attgtatttg tttggaatgt attgcaaacg gaaaagcatc taagaaattt aatggcactt
    53761 ttattcaaga tgttgaaaaa gtaattgatg atgaagagaa aactaaagaa ctatttgaga
    53821 gaactcctgg atatgtgagt tggcagggcg agtattggct tacttgttgt gatgactatt
    53881 gtgcttatat tggaactgta ggaataaagg aattgcaaga gatgggcatt gtggaagagg
    53941 cacttgcaga atatgaaaat cgtaatgaga gatatgaaaa tattcgtgag aatttaacga
    54001 aaaacggttc tctttgtggg tatttatttc agtgtttaca ttgtggtaaa tatcgtttat
    54061 gggtagatgc ggattaataa attccagttt ataattacag attatatgta atagtagaca
    54121 agttgacata taatagattt gttaaaaata tatatacata catgtaattt aatcaaagta
    54181 ctgacagtgg ggtcttttaa cctaccagtt ggggcatata tattgatgct aaatatgagg
    54241 gatgttatat tttaataaaa aagataacat ccttttttta gtgcattata tcgagtttta
    54301 aataataaat gaaggaggat taatatgaaa aaatataaag ttatttttat agtattaatt
    54361 ataggtatta taagtgtaac agggtttgtt gtatataaaa actgcattaa accatggaaa
    54421 gatgctgaaa catatattga taagtatatg gtaaaacaag atatttcaaa agataatata
    54481 aaaagtatta caaaagaaaa agccaagaag gcaagttacg aaggaatact atacaaagtg
    54541 tattacaaag atgaccctcg atatgagtat caatattttt atagtgataa ttattatgct
    54601 ttatatgtaa ataaagtaat gttacaaatt tatgatatgg aaaataataa taaactttta
    54661 agaagtaatg aggaattaaa aagtgtaaag tatccaccaa tatatcttaa atataagcca
    54721 gataaatgat ttatgacaaa atagaatgat ttttattaaa atttatttaa aaatatcact
    54781 agagcgttta aataaaacta aatttaagta tttatatatt agtatatctt actagtgttt
    54841 aaacaaaatt aaatttaagt atttatatat tagtatatct tactagcatt taaatgaaac
    54901 taaatttgaa gctttaccta ttaatatatc ttaatagtga ttaaataaaa ctaaacttaa
    54961 gactttatat gttaatatat cttaagaatt tatttgttaa catacagttc attatattta
    55021 aaagcattac tatgataatt cataatagta aaatagataa tggttcagac aatattataa
    55081 atattagtga cggtaaaata gtatcaattt agtatataaa ccttgtcaga taatcgcata
    55141 acagagcttg tagttataga ataaaaaaat atctaggaaa ccgttgacag atttatatgg
    55201 atagtataac atatagaata tgaaattaaa caaaaaagaa ttttaattat ggcgacgtag
    55261 tcataatttt gagtatgtta ctgattagca ggcagaactc aagtatatat gtgaaaaata
    55321 gagggatact ctatacatat atgcttgagt tctttttatt gaaaggagga atatatgaaa
    55381 ataattcaga ttttaaataa taatgtagcc ttagtaaaaa gaggtaaaaa tgaaattatt
    55441 gtatttgtta aaggaattgg ctttaaaaaa agagtgggac aagtaataaa tgaaaatgaa
    55501 atagagagaa catatatact agattcatac gatatgctag aacactttag ttatctacta
    55561 caaaactcag actccaataa tatagttctt attaatgaaa taattgaata tggtgagaaa
    55621 gctttaaata taaagtcaag tgattatcta agcttaacct tactagacca tttagagttt
    55681 ttacttaaaa gatgtgaaaa gaatcaattt ataaaaagtc ctttggtatg gaatgttaaa
    55741 atattttatc caaagcattt tgaaattgga atgcatgcac taaaattaat tggtgatagt
    55801 aagggaatta atcttcctga tgatgaggca gtatcaatag cacttcattt tgtaaatatg
    55861 gaggtaaata aagagtctca tgatagtaca attgtggagt tgagaacttt agcagatata
    55921 gtttctataa taaaatatca ttttaatgta gagctagatg aaacttcaac aaattatatg
    55981 agatttacta ctcatctaca gtactttatc caaagaatta tgtcagatga agcttcaata
    56041 gatgaagata attctataga tttatataaa caagtaagtc aactttatcc aaagtcattt
    56101 ggaagtgttc aaaagataag aaaatatata aaatcacaat ttaatgtcga tatatctata
    56161 agtgaagaaa cttatttaat gttgcatata aatagggtga ctcaaagact ggaggcaaaa
    56221 tcagatgaaa tataaagatt taaatgaaaa tataataaaa cttatagggg aaaaagaaaa
    56281 tataaagtcg gtagcgcatt gtgttactcg tttaagattt actttaaatg ataggagtat
    56341 cgctcaaaca gaagaaatta aaaaattaaa aggagtaatt gatgtagttt ctaatgatgt
    56401 tgcttatcaa attataatag gtactcatgt tgtagatgta tataacgagt ttatgtctat
    56461 gataggttta agttcaagtg aatcaagtat aaaaagtgaa agaaaaaagg gaattagagg
    56521 tatcaaaggt atatttaatt ccatctttgt ggtagtctca gagactatga cttcagtaat
    56581 tgaagtacta cttgcagctg gtatacttgc aagtatatta gcacttttaa atatgtctgg
    56641 catacttcag agtgacagtc ctacatatca aatattagat acattaagaa gtgctacatt
    56701 tcacttctta ccagtattaa ttgcaatagc atcagcaaaa agacttaatg taaatcccta
    56761 tatagcagta gtgttagcag ttacgttatt atcttcatca atagatggtg tagaaggatt
    56821 aagtttattt ggtataaatt tacaggctac aacttatgca aacagtttta ttccaatact
    56881 tttaggagta tgggcaatgg gaattataat tgaaggtttg aaaaaaatat tacctaaagc
    56941 attacactat tttttagttc cagtgttatc tttaataata actctatcag ttacattaac
    57001 tgtatttgga cctattggta tgtggattgg tgatggatta aactatgcat gtatgttttt
    57061 aattgatacg ttgggtaatt ggagtgttgt tgcactgtat gcagctttac aaccactctt
    57121 aatagttttt ggtgcagcaa actttactat gcctatatct ttaaattctg tgacaacatt
    57181 ggggtatgac ccaattttta tgggcgctgc aacaatatct gatattgcag tttgtggtgc
    57241 aatgtttgga tatttcttaa aaactaggaa taaagaacaa aaacaactat ttggtacagt
    57301 aagttttagt gcacttatgg gagttacaga accttcagtg tttggtgtgt ttatgaaata
    57361 tagaagagca tttgtagcag taatgatagg tggaggtata ggtggtttaa tagcaggttt
    57421 agctcaagtt aaaacatatg gaatggtttg gggattagct gcattaccaa cgtatcttgt
    57481 tggaggagag gtatctaact ttacatttat gataataagt gtagtagtat catttgtagc
    57541 agcaacagca gcttcctatt tactaggaat accttcagat gaaaaagaag aagttaaggg
    57601 tgataatgaa aaagaattag aactaataat caacgagaac aattcaagaa ctattagtat
    57661 tggaaatgtt gcaaaaggtc aggtaattgc acttggggaa gttaatgaca aagcattttc
    57721 ctctggagca ttaggtaaag gggttggagt tatacctagt gaatcaaaat caactgttat
    57781 atctcctgta gatggaacta taactatagt atttccaact aaacatgcat atggtatagt
    57841 gactgatgaa ggattagaaa tattaattca tattgggata gatactgtaa acttagatgg
    57901 aaaattcttt gaaagtcttg taacacaaaa tcaaagggtt aaaaaaggag atgctttagc
    57961 agtatttgaa tctgataaaa ttatagagga aggctttgat tctactataa taactgtagt
    58021 tacaaatact agcgattatt tagatgtaat ctcatcaaat gatgaatcag aagaattatt
    58081 aactgtaata gtataaattt taggagggaa aattcatgaa tattaaagat acatttttct
    58141 ggggaggaag tattgcagcc catcaatgtg aaggttcatg ggatagtgat aacaaaggac
    58201 ctgcaattat ggactttgta actaagggct cttatgaaac gccaagagta attactgata
    58261 aaatagaaga aaaattagat tatccatctc ataatggaat agatttttat aatagatata
    58321 aagaagatat agctttattt aaagaaatgg gatttagtgc attaagaata tctatagatt
    58381 ggtcaagaat ttttccaaat ggagatgatg aaaatcctaa tgaattaggg attaaatact
    58441 atgaaggtct gatagataca ttaatagaaa ataatataga acctattgta acactatatc
    58501 attttgagtt acctatgaat ttagtacata aatatggttc atggaataac agaaaactta
    58561 tagatttgta tttaaagtac agtgagactg taataagaag atttgatgat aaggtaaagt
    58621 actgggttac atttaatgag atgaaccata ttgaccctca aacagagcac tcggatattt
    58681 ttacttatat gatagcaggt attaagtata gtgaaataga aaataaggtt caaacattgg
    58741 caaatgtagg gtataatatg actttggcgg gtgtaaaggt tgcaaagttg gctagagaaa
    58801 tcaatcccaa caataaaatt ggatgtgtat ttggactaaa tccaatttat ccatacaatt
    58861 gtaatcctag taatgtgtta aatgcatttt tagataatga ccgtgattat tatcaaattg
    58921 atgcaatgtg caatgggaag tttccacaat ataaattaaa agaatatgaa aaaaataata
    58981 taactattga agtgactgat gaagacaaaa aagcatttaa agaaggtaag ttagatttta
    59041 taggacttaa ttattatttt tcaagtgtat ctactccaaa agaaaattta tcaggtgata
    59101 aatctttatt tggtgggatt caaaatccat atttggaaca aagtaagtgg gggtgggcaa
    59161 tagaccctat aggtttaaga tttaccttga actatattta cagaaagtat caattaccta
    59221 tcttaattac agaaaatggt ttaggggcat atgataaaat cgaagaagat ggaactataa
    59281 atgatgatta tagaattgaa tatttaagta agcatctatc tcaaatgaag tctgcaattg
    59341 aagaggataa tgttgaatgt tttggatatt tgatgtgggg accaattgat ttagtcagtg
    59401 caactacagg tcagatgagt aagagatatg gatttatcta tgttgactta gatgatgaag
    59461 gcaaaggaag ttttaagaga tataagaaaa aatcatttga ttggtacaaa gaagtaataa
    59521 aatctaatgg agaagtttta gatttttcta cggatatagt agtagggtag gaataagata
    59581 aatagaagtt aggaactaat gttaattagt gtctagtaaa gcatttaaaa tagagtatag
    59641 ggtctttaaa gtaaagtgtg tattcttctt aaaagtaatg gcaactaaaa ttactataaa
    59701 aaggagaata cacatttttt atgtttatac ttaagtaaat atttagacat attcatagta
    59761 taatttactc attatataaa aatagtatga tttactcact atataacttt ataaattttc
    59821 tggaaaaatg tcagaatata ttgacaaaga aaagatttaa aattataatc tatattaaga
    59881 atagtttgac aatataaaaa caagtatttt tataaatagt gaaattattt ttattgtaaa
    59941 tttaagaata atttaggact actataaaga taaaggtata gatgtcatta tatgataaat
    60001 catacttgta tagaaagaat tttaaagtat ggcttatcat tgatttaata taataaataa
    60061 tttttgtttc tagtaatagt tcctaggaat aagatatcta aattcgttta gaaatagtct
    60121 aatttacaaa ggaggggatg cactaataga taaaatttct atataaagaa gacttaaagt
    60181 gaagtatatt ctgataatat tggtttaatg ggtatattat tatttcgttt tagatatttt
    60241 aagaataatt taagatgttt ataaaaatgt attctatatc taatatttaa ataaatataa
    60301 gtcttccaac atgtatacta atatagagag tagttgaagt acaattctaa ctcgtaaaat
    60361 tatgtagaaa gtaaaaatca aaaagaaatc tagtaagttg ataactatag ttaatattta
    60421 gagagttaac tctagttata tttatttaga tattttagga ataatttagg acgcatataa
    60481 tatcatcaaa aaatatcaag ctataccata tgtagttaag aataactgca taatatacat
    60541 tttataatta ttgttttatt gataaaaaat tattatattt aggaggaaac aacaatggaa
    60601 aatttttgga atccacttac ttgctttact gtatgtgtaa tgatttatgc ttttagtgag
    60661 tttttatcta agaaaacaaa aggtgcaatt tcaacattgt tatttgtatg tattatattt
    60721 ttactaggat tttggacaaa tattttacca aaagacatta caggagcatc agggatatta
    60781 gctgcaatga gcaactttgg tatagcttta ttaataacta acttaggaac acttataaat
    60841 cttgaagact tatgtcatga atggaaaacg gttgtaattg cattagtagg tattgtagga
    60901 ataggggttg gctgtttaac agtgggtagt atgttatttg gtagagagta tgctttaata
    60961 gcagcacctc caatagcggg ttctactgtt gctggtatta tcgtaacaac tgttgcagaa
    61021 gctgcaaata gacctgaact tgctgcattt gtaattctag tattatcatt tcaaaagttc
    61081 tttggcattc cgataactac atattgtata aataaagaat taaaatttaa aagagataat
    61141 ggggattttt tgaaagatga gtcaaaaagt aattttaaac ttccaagtat gaaaattttt
    61201 aaagaagatt taggtaaaaa atcatctact ttagtgtatc ttgcaaagct ttcatttgtt
    61261 gctatgattg gtaattttgt aggattggct actttaatac caggatttac ccctgcaaac
    61321 tattatttaa atcctaatat agcatgtttg ttagtagggt tgatttttac acgaataggt
    61381 tttttagaaa aaggaatttt agataaatct caatctaatg gaattataat gtttggttgt
    61441 atgttgatgt tacctggagg acttgctaag gtaactccaa cagcattgtt tgggatgatt
    61501 gttccaacta taggaatact tgttgtaggc tctgtattta taatattatt tactgcaatt
    61561 gtaggaaaac tattgggata ttctccaaga atgtcagctg caattggtgt aacttgtatg
    61621 ctagcttatc ctgcaacaca gataatttcc aacgaaggta ttgatgctat ggaaggaact
    61681 gaagaagaaa aacaaagggc aacagattat ttattaccaa agatgattat aggaggattt
    61741 gttactgtaa ccattgcatc agtggcattt gctagtataa taggtccaat tatatttggt
    61801 tgatagtaaa tagatttata ggaggaatag aaaatgatag gaagtatatc tataaatgag
    61861 atagataaaa aaagattcaa acttgatgat ttaagtaaga aaatatggga aaacccagaa
    61921 aaagcattta aagaatttaa agcatgtgaa aatacagcaa actttctaag aagtgaagga
    61981 tttgatgtgg aagtaggtgt aggaggttta gccacggcta ttagagctag ttttggttca
    62041 ggtaaaccag ttataggttt tatgggagaa tttgatgcat tacctggttt aaatcaaaaa
    62101 gtttcaacaa agcaagaagc atttgaattg ggtgcatatg gtcatggatg tgggcataat
    62161 ttattatgta cagcacatgt aggggcagta gtaggactta aaagagagat gctagaaaat
    62221 aacttaagtg ggactatagt attttatgca tgtccaggag aagaacaatt aacaggtaaa
    62281 ggatttatgg ctagaggtgg agcatttgaa gggttagact tagctataaa ttttcatcca
    62341 aataaaatta gtgaagctac aattggtact tcaacagctg ttaactctgt aaagtttcac
    62401 tttaagggaa agactgcaca tgcaggctca gaccctcaaa atggaagaag tgcactagat
    62461 gctgtggaac ttactaatgt gggagctaat tatttgagag aacatgttac ttctgatgta
    62521 aggattcatt atacaattac agatggagga gtagcaccca acatagttcc tgataaagca
    62581 tcagtatggt attatacaag agctttaagt agagaagctg tagaaagtac atatgaaaga
    62641 cttgtaaagg tagcaaaagg agctgcaatg atgactgaaa ctgaagttga agtagagttt
    62701 ttaggaggat gttataatac tttaaacaat catgttttag caaatcttgt atcagaatgt
    62761 atgaatgaga ttaaacaaga gccttggact cgagaggaat tggattttgc agctgaatta
    62821 gatagacaaa gcccacaaca atataaggct atgataagta aatataattt gccagaagga
    62881 actcatctat attatggtgg aggaaatgtt acaaacttta atagttatgg ctctactgat
    62941 attggagatg taatgcatat agttccgaca gcatactttt ttacagggtg tacgaatcta
    63001 ggagcaccag gtcatagctg gcagtttaca tcttgtgcag gaagttctat aggagaaaaa
    63061 ggtatgatat atgcatcaaa aattatggct atgtttggag ctaaaatatt aaataatcca
    63121 gagatagcta aaaaggcaaa agaagaattt gataaatcta tgaatggtaa aacatataaa
    63181 tgtcctattc cagatgatat ttcaactcct taaaaagaca tgaaatttaa tatataaaat
    63241 tataattttt atatcagcat catttcatta ctaaaagaaa gtgagatttt gctgactatc
    63301 tgattaggag gaaggaatat gaaaaatttt tttaaagaag cgcagtcaat agaaggggaa
    63361 attattagat ggagaaggta tttacatgaa aatcccgaaa ttggttgcaa tctgccgaaa
    63421 acagtaacct ttgttaccag tactttagaa aaaatgggat attctccgaa attggcgtct
    63481 aataatggaa tagtagctgt tttagacagt gaaaatggtg gaaagacctt attattaagg
    63541 gcagatatgg atgcacttcc tattatggag gagacggatt taccttttaa aagtaagaat
    63601 aaagatgcat ctcatagttg tggacacgat aatcacacag caatgctctt aggagcagct
    63661 aaaatactta tggataataa gcacttactt aaaggtagag taaagtttgt atttgaacca
    63721 gatgaagaga ctaccagagg tgcaaaatca atgattgatg atggtatatt agaaaatcct
    63781 caggttgatg cagctatggc atttcacagt atggtgggta aatttcttaa cacaggtcaa
    63841 gtagcttatt cacgtggtcc agctatggca tctgcggata tatttgaaat aacagtagaa
    63901 ggaaaagcaa ctcatggagc aagccctgaa tttggagtgg acccaataaa cataatgtcg
    63961 catatacaaa tagcattaaa cactatactt tcaagagaaa aacctcagaa agaacctgta
    64021 gttttaacta ttggtatgtt taatgcagga aacgtaccaa atgctatacc aaataaagca
    64081 tctatgtcag gaactttaag aacatttgac caatttgtta gagaaaaatt aaaaaataga
    64141 attattgaaa tatctacagg aatagctaaa tcatttggag gaaatgctaa agtggaattt
    64201 aaaatgggga ctcctgcagt tataaatgat ttggatgtag gagatgagat tgtatcttat
    64261 gttaaagaag ttataggaaa tgaaaatgta atagactttc catctgcaat gggttcagaa
    64321 gatttttcag agattttact aagggttcca ggagtatttt tatggattgg aatgggaagt
    64381 attagtcagg gatataattt tggtatgcat aatcctaaag caatttttaa tgaagaggga
    64441 ttagtttatg gttcagcttt atttgctcat tgtgcagtaa aatggttaga aaataatttt
    64501 agtagataat aacataaaat attattaaat attataaaag gtatatctta aaaagatgca
    64561 aagatatacc ttttagaaag tcatatataa ttttacttaa tattagatga taaaatattt
    64621 ttatgcattt tggattttaa tatttatttt ctgatataaa taatttgtat accctttcag
    64681 gtctaccttt tgttgagttt tgtttttcat ataatatagt agcgtttcca gactttaaga
    64741 gactacttag aaatctatta gcagttctaa ctgttacatt taaacatgaa gataattcct
    64801 taggagtaac ttcatctctt tgtagaattt cagtaacaga tataatcttt tgaatagtaa
    64861 gagtagacaa tttagaactt ttggcaattg tatttatatg tggagttact ttatttgaaa
    64921 cagtaagtaa cttatcacac agtaaaggtc ctattgtctc ataattttcg ttaactaaga
    64981 aactgtaatt taaaggattt attttagatt ccttattagc acttatggca ctagacatag
    65041 cttgctttat atcattacca attccatatc caacacatac tttaatattt gtactatttt
    65101 caatagattc ttttatataa catgcagtaa aatttttagt taatgattta atcgtttcac
    65161 atttagtgaa aattttaaaa gaattactat ttttttcaat tataaaatcg gttaatttat
    65221 cttttttaat actatttaat attttataaa cttggtctag agtagagtca tcataatttg
    65281 tatctttaac tgttatatat attacacttg gttgatttcc cttcattcta tgtaaatgaa
    65341 tatcttttat taagttatta aaagtatttt ttaataaatc tatatcaggg tatatgaaat
    65401 gaaagtttac tcctgcattt tgtaacatag gaacaatact actaaaacga gtagtagaaa
    65461 aatcgatttt cccttcattc catagattaa tatgtttttt tgcaatcttt ttttcaagtt
    65521 ttgctatgtc agataaactc attttagatg cattttcatc aatactatcc attaagtctc
    65581 caaatgtgcc atttgataaa taatatgata tatcttttgg attatctgcc cagtctgtta
    65641 agtcaaagta cgctctagaa aaatctaatg tattatattt aaagataagc tttagaaaca
    65701 tatcatagta actttgtaag tcagtaccaa aatcaactag aggtttttta atagttccag
    65761 ccttttttgt aatagctttt ttgggaatgg ggccactaac tgcaaatcca tcaaacctat
    65821 cttctatttc taaatataaa tctccaacat gagaaaaatc tctatagata tatatttcaa
    65881 tttctgcatt aatatttaac ttttttatag aattatctac aaactctttt aaaaattcgg
    65941 ttgttatgac tgctattttc atcatagatt acttcctttt caattattat aattatttta
    66001 tattaaatat tacattaatc tattgttcta gttaaaatct tatttcaatt aaattcaatt
    66061 aaaataaata actctttata aaaagcaatt atttaggtag aggaatattt gctaacttta
    66121 atagtctttg ttaactttaa ttttatttaa gttattatag tcttactaat tttataattg
    66181 tagatttaac tactttatgt tcttttattg tttatgtagt tgatttagaa gttattttaa
    66241 ccatttattt taattgaagt tgtttgattt ttaaatcctt tgtgtaatct ttgtttttct
    66301 agccatgata aaagtatttc tatttgtatc actatatata ataatatcat gacaaaatat
    66361 ttattgtcta actaattata atctatccaa aatgaaaatg ggtgtgagat attattacaa
    66421 caaattgtat tagtattaaa aagattaaaa aattaaaaaa ctaaacagtt aaataattaa
    66481 acgattaagt gactgtcata taacaattta taattttatt taacagccac ttaggtattt
    66541 aagagcgata gaattgagtg tatatcaaat tataataatt tcctagtaaa taattgaaaa
    66601 ataaggtagt ccatttttat atttgatatc tggtttacct tgaataagtg gatatagata
    66661 atttagggct tcatcagtta tataattaca ttcttcattt atccactctt taggaaaata
    66721 ttttgtcttg ttagctattt tagaaatatc agtatgacta acttcatact tataaggatt
    66781 attgcatgtt ctattaatga tagccataac tcctgtatat ccttttttag atagttctat
    66841 cccatatgca ccaacttcag ctgcttgttt taaatcagta tctgaagcta aatgcatagc
    66901 acatctttgt attacaccaa gttctaaggt ttttactctt gttgtaattg atgatgatac
    66961 tataagattc tttagatagt tgcttactcc acctaattgg gaatgaccaa atttatcatg
    67021 agcagaagtt ttttgttcgc atataaagtt gccgtattta tcccttatac cttctgacgc
    67081 aactatataa gccttatttt tttctttaaa tatttttcta acatcttcta taaacttatc
    67141 ttcatagaaa tcaatttctg gaaggtatat taaatcaaca agtggagtat cattaagtct
    67201 agctagtgaa gaagaagctg ctaaccatcc agtatctcta cccatagttt ctactataaa
    67261 tataccatta tttttgtata tagaaaaatc taagtatgtt tccattatta gtgtagaaat
    67321 aagctttgca gcagaaccaa atccaggaca gttgtcagtt cctaataaat cattatctat
    67381 tgttttagga atacctataa attttatttt acaagtagtg tttttgcagt attgagaaaa
    67441 tttcatcact gtgtccatgg aatcatttcc gcctatataa aataatgtat ctatttcata
    67501 ttcatctagt atatttataa ctctatcata atcataagaa tttattttat aatcagccag
    67561 tttgtatcta caagaaccaa gaccagacga aggtgtttgc tttaaattta atacattatc
    67621 tttgtttaag gagtctgaat ctattatatt tttgtttaat ataccttcaa tcccattgat
    67681 accaaaatat actttatcaa agtatttagt ttctaaattt ttttcataaa taccaactgc
    67741 agaagcattg ataacagctg tagggcctcc agattgggca ataatacagt ttctcatttt
    67801 acatctccct ttcattaata ttgttatgaa tggtactttt tatcgagtaa atttatattt
    67861 atagtctgat tatatattaa atgaactagc tatatcaatt gagttagtat agacaataaa
    67921 tgccataaga atgtggtaaa aaactaactt tttatataca attaatgtct ataatttacc
    67981 acaatataaa ggtactttta aggagtagtc aaagtgttgt gaaaaaaaat atatcagtgt
    68041 aatattaatt tacaaagcaa aataagttca cagttaacaa aagcagaata agttcataaa
    68101 agaaatatat acagcaataa aagtaatgct aaataaaagt aatactggat taaaaaatat
    68161 taaaaaaata ttaaaaacta atatttaata ctaattaaag taaaatatgg aggtatacaa
    68221 atatgaaaca cataaaaata gcagcaggat tagcacatgt aaattacggt catatatcag
    68281 ccgtagttaa agaagcaatg gatgcaggtg tagactacgt acattcagat gcagcagata
    68341 tgcatgactt aaaaaatatg caacttatgg gtggtcatca aataatagaa gcaataagac
    68401 cagtgacaga taaaccaata gaatgccata tatacacaag agattgtgat agattattta
    68461 tagaaaaaat agcagcagca ggatgtaact tgttgataat accagcagaa cattttttag
    68521 gtgctcctct tgcatacata ataaattact gtagagaatt tggtatgaaa gtaggattaa
    68581 caattggatg ttacacacca ctatgttttg ttgatgaagc tatatatgat atagatagat
    68641 tgcaaatagt cgttcatggt gttgatgaaa ctgatggaaa agataactgg ggatggagaa
    68701 agagtgctgt tgatttagta aaaagagcta gaaaaatgat agacgaaaag aatcctaagt
    68761 gtgaattagc aatagatggt ggactaagag cagacaatat ggagccatta atagaatgta
    68821 atccagacgt tgtaatatta tcttcagcaa tattcaagga taaagatggt ataacagcag
    68881 gtgttaagaa ttgtagaaaa gctatagatg aagcagctac aaagtttggt ttagaataag
    68941 ataataaact atgataaaag agatgctttc ttaatgtttt aaggaagcat taattttatg
    69001 aaaaactaca ggaagctaga ctaatttaat tgatttttta tactgaaaca atataatcat
    69061 aggaggttat taaatgaaaa aagaaatgat aaaagattat ttactgataa caatatcagc
    69121 atttttaatg gcattagcag ttaatttttt ctttgcagaa catacattag ctccaggagg
    69181 gataacagga ttatcagtcg tacttagcac attcttatca atgcctgttg agaatatatc
    69241 attaggaata tctatgccac ttttagtaat gggattatta tttttaggga aaggttttgg
    69301 aataaaaaca ttatatataa ctcttatggg cccattattc ttaaaagtaa taccacaaac
    69361 tcacataact gacaatctat tagtagcagg agtgataggt gggttattgg taggaactgc
    69421 tatagggata gcaataataa ggggctgtag tactggtgga actgatttag ttgcaatgct
    69481 tattaataag gtaattaagt ttctgaagtt gccagttata ttatttatgc tagatggatt
    69541 tataatagta gcgtctggaa taataagtaa gaattttatg atatctatat attcattgat
    69601 atctttatta ctcataataa aaacaatagg atttgtaact acaaagtttg gtaagaatac
    69661 tgaagaaatt aataatataa ataatgcttg tgctcaataa aaataataaa atttacttta
    69721 aatataaaag tttaaaaaat ataaaagctt aaataaaaag attaaatata aaaaatgaag
    69781 gtgtctcaaa atgaattttt tagttcatga ggcacttttt ctatgaaatc aaatatattt
    69841 ttatcatttg gacaatgaaa aataggttta tctctatgtt gagacaagcc tatttttgtt
    69901 tatttataag ataatatttt atttttttca gaatatagtt tttttataat tgtactaagt
    69961 ctagaaatat cattcttact taaaagagca tttatattta tcagttcagc attatgttca
    70021 aagtctacag gagcagtagt tagtattaag tccacatcat caaagttcgt aaatgaaata
    70081 gaagatagag gtatagattt aactatatta atctgattaa attcaaaact taacttttgg
    70141 actaataaat tagatacacc atcactacag tgacatatta aaatagtatt taggggagat
    70201 ttgcttctat ctattgctga tattaaatat aaagcaagat atcctatttc gtcatcattg
    70261 acttcataat tcatcaactg tttgataaca gtattagact ctttagcagc cttataagta
    70321 taaggaaatg ttctctttat atcatttaat atgggatttg taatagtaaa cccatagttt
    70381 attctgtgta gaactgattt aaggtgatta gcaagagact ttattaatat taaatcgtcc
    70441 tttaagttta aatttagtat acttccccaa tgaacagcta ttgcttcaga tagattatac
    70501 tctgtaattt cttcattttt aagaggttca agagtagtag ttttctttat tgatttaagt
    70561 aatccttcta tatgaagaag gatataacag acctcttcat caataaattc tacgtcaaaa
    70621 gcttcactta ggttaacaca taaaattttt gatttttcaa agtattcatg ttctaataat
    70681 tctctaaaaa aaccttcaga taagttaata tatcttttaa ttgaaattct tttaatacat
    70741 atagctatat gtattaagaa gtttatataa tactcatcac taaggttact tttttctact
    70801 tgtaaggtgt gtagagtgat ttgagataat ttctcaaaat catagttaaa tagctcctta
    70861 aatatttttg ttgatggggt atctttgcat tcattagatt tcgagaataa tatttcttta
    70921 agttcagtgt aacttttatt aacagtagca agttcaaaaa ttgcttttcg aatatctttc
    70981 tcttttccct ctaaatatac tccattattg gtttttctaa ctagagtcac tttaaagttt
    71041 tgcaaaaaat tttgaataac taccaagtct ttatgcacag tagctctact aacatgtagt
    71101 tcattgcaaa tatcacgaat cctaaactta gaatttttaa taaataattt acttagaata
    71161 tacctttttc tatcttcagg agagtatgca tatatacaat ttgatttatc attgatatct
    71221 ctaataactt taagttttat atcttcatta cctagaataa taacccctga accagttttt
    71281 ttatctaggg ataaattaaa ctctaaaagc cattcatcta aaataacaag gtcattacga
    71341 atagttttat tactaacttt taattcttcg gcaatagtat ctacagtaat atagtctgag
    71401 ctgttgagta ataattcagc aatatctaat aatcttttgt tcaatgcaaa ccctcctaaa
    71461 tcttagttac tatttattaa ccttggacca atctctttca aaagtattgg caccatctat
    71521 tgtgagctgg ttaaaagaag cttttttaaa taaatcatat gttacagctg cataatcaca
    71581 tccacaaaga gatgcttgag ttaagtggaa tacattttta atagaagctg caacaacttt
    71641 agtattatat ccatttattg atataaggtt acatatttct gtaaggcttt ttataccatc
    71701 attcccattt tcatcatttc tacctataaa agggaatagg taatcagcac ctgcatttat
    71761 agctaatgat gcttgattta cattgaaaat caaggtacat gcagttttta tacctttact
    71821 atttaatatg tttataagtt ctaagccaac ttcagagaaa tttattttta ttatagtgtt
    71881 tttatttata tttaatatct tatcacatga attaattaat tcgtataaat tatttccaat
    71941 gacttcagca gttaatattt ctggatttaa attagcacat gtctcaataa attcatggaa
    72001 gtttactttc tctttaagat acatagatgg attagctgtt attcccttaa atccatactt
    72061 taaacacttt tgaatttcat caagattagc actgtctatc aaatatttca taatttaatt
    72121 ctcctttaag ctatttgtca taaaaaagtg tatatactct atttttatta ttaagtcaat
    72181 tatacaataa gattgattat aaaattataa catgggtact taataaaatt tacataatga
    72241 tatggtaata ataaaacatt tattgtctaa taattgccat aagctttagt aaataagagt
    72301 taacagtgaa ggtattgcct taaaaatcct atgatatgta taatttgaat atgaaggcaa
    72361 taatttaagg gaggaaaaat atgattaact tttatcaacc atcaagaata aattttggac
    72421 aaggaacttt aagtgaatta cctagaataa taggaaaata tggaaagaaa tgtttgttag
    72481 ttactactcc aaatgtagag ccattagaca agttatataa aagagttaca ttgaatttaa
    72541 tagaaaaagg tatagaagtt gtacactttg atagagtaga gccaaaccca actgtagaat
    72601 taataaatga agggtttgaa ttagctaaaa aagaatctgt agatgttgtt ttagctgttg
    72661 gaggaggttc aagtatagat actgcaaaag tattagcatt gacttttggt ttagaaaaga
    72721 tagattggga ttatatgttt agtacatata caaatccatt taaaatatac gataaggtaa
    72781 gtgaaaaaga attaccatta atagctgtat caactacttc tggaacagga agccaagtta
    72841 cacaagcagc agtaatatcg agaggaagcg agaaaaatac aatatttcat caaaattgtt
    72901 tctcaaaaga atgtatagtt gacccagagc ttatgttaac tctgccagag agaattactg
    72961 catcaacagc atttgatgct tttactcatg catttgaaag ttatataaat ccaaatgcta
    73021 atgattttac agagataatg tctgaaaaat ctatggaatt agtcattaac tatctaccta
    73081 aagtaatgga agataaaaat aatatagaat acagaacaaa gttagcagta gcagatacat
    73141 taggaggaag ttcactggca aatgctggag cagcagcacc acatccacta agtgaaataa
    73201 taggaggagt tacacatatt cctcatggtg aggctttggc catagtgttc ccaaaatttg
    73261 cagaaaagtt ctataaggat aatatagaga aatttgccaa agtagcgaga atgctaaacc
    73321 aagaattaga aaaagtggaa gatgatgaag cagctaaaac tttaggaaat gaaatagaaa
    73381 gttttttaaa gagagtggga cttaagacaa aaatgtctga gtttaatgta acaaaggaac
    73441 aattagaaca aataacaagc tgtccagttt taggattttt accttttgga aagaaagaag
    73501 accttgttga aatattagaa aaatcttact aggatgtgat acaaatgcga tataaattaa
    73561 tttgtactga tatggatggt actttgatgg gtaaaggatt tgaagtatca gaagaaaata
    73621 ttaaagcact aaaagaagtc atggaaaagg gtatcaaggt agccttagtt acgggaagac
    73681 cttataatgc tatgaaatat tttacaagtg ttttagggga tgatatatat attatatcaa
    73741 ctaatgggac atattttaaa ttactgggat atgagtataa gaaggttttg agcaaagaag
    73801 ctctaaagaa aatctataca ataggtgaaa agtataattt aaacaaacat tttaaaggct
    73861 gtaaaatagt tatatccaac aatgaaatag gtgaagaaca tccatataga ttaataaata
    73921 gtaaaaataa agaagaagac agaattgaaa taatagaaaa tgcaagttgt gaaactttat
    73981 tagaaaaagc tgataatgaa attttaaaat gtatactttt ctcagaaaac gtagattctt
    74041 tgagagaagc aaaggaagaa tttaaaaaac aagaagattt agaagtagta agttctggaa
    74101 agataaattt tgaagttatg agcaaaggta cttcaaaagg tattgcagtt aaaaaatttt
    74161 gtgatatatt aggtatagat agcgaagaag ttatttgtat aggtgataat gaaaatgata
    74221 tatccatgat taaatttgca ggtcttggta ttgctatggg aaatgctaca gatgaagtaa
    74281 aatctatggc agattttgta actgatacta atgtaaatga tggtgtagca aaagctttaa
    74341 gaaaaatatt atcataaaat tttataatgt ggagagtgtg ttatgtttaa tatatttaag
    74401 aaaaaagaaa ataagattga gaaaatatat agccctttta agggaaattt agtgaactta
    74461 gaagatgttc cagatgcagt ttttgcccaa aagatgatgg gagatggagt agcaataata
    74521 ccaagtgaag gtaagttata ttctcctgtt gatggtgaaa tagtcaatgt atttgataca
    74581 aagcatgcaa taatgattaa gagtaatgat aatacaaata tattaataca tgtaggttta
    74641 gagacaatgt cactagaagg aaagccgttt gatgttaagg taaaggcagg agataaggta
    74701 aaagctaaag atttaataat ggaagtagat ttagatttta taacgtcaaa tgatttaaat
    74761 ataataactc ctgtagttat aatggatgat gctgattctg ttaagagaac agtaaaagat
    74821 aggatagaac ctggaaatgt agatattaat agcataataa tggaagttga atagatataa
    74881 gaagatgtag ctaaggctac atcttttttt atgtattttt tggaataaac ttacattaaa
    74941 aaagacgtaa tagataagtt aaaatattag taataggtat agtatgattt tgtcataatc
    75001 tgttgattgt ttaccgtatc attatggtaa cttagagaag tatttgaaat attgaaaaaa
    75061 taatattcaa aatttataat gtagatatga actgaaatgc tttgtaaaat taatataaag
    75121 gggtgataaa taattaagat gatagtaaac aaagaactaa ttattgatta tttaaaatcc
    75181 aatcaagaaa atatcataaa tgatattaga agtttagttg aaataccttc aattagagat
    75241 gaaagtacaa cagatataaa tcaaccattt gggatagaaa taagaaatgc cttcgataag
    75301 cttattcaaa tagcaaaaga caaagatttt gttgtaaaag actttgatgg atatgcaatt
    75361 catatagaat atggagaagg agaagaagta gtaggggtgc ttaatcatat agatgtggtg
    75421 ccaatatata ataaagaatt ttggaagagt aaacctttta aagtatgtca aaaagataac
    75481 tatctttatg gtagaggagt taatgacaac aaaggacctt tgatagggat tttatatgca
    75541 ttacttttct taagagaact taatgaaaag ccgaagagaa agattagatt gatagtgggt
    75601 ggagctgaag agacgacttg ggaatgtatg gagcattact ttagtgtcaa tgaacagcca
    75661 aaatttgcat tttctccaga tggaaacttc ccaatagtaa atggagaaaa aggtatttta
    75721 tacttcaatc taagaaagaa aatagataaa gataaattta gaaatcacaa tttagttgat
    75781 ataaagtcaa acaaagaaga tggatttgta tgtgacaaaa ttgaggctgt ttttaaaact
    75841 aatgataaga aagatttagt agaatcatta gcttattata cagagataga agaactagaa
    75901 gaaggtaaag tattagtaag atatacagga gaaagggctt tatcgagaaa tccacacagg
    75961 tcatataact gtgcatttag tttagcaaaa gatttagaga aaattaaaaa actaaatgat
    76021 aaaggcgtta taataaggga tattttaaat tcatacttta cagatgataa tcatggaaaa
    76081 aaattaggga tatataaaga agatgtagat atgggagttt ctacaatatg tataatgagt
    76141 atcttcttag agaaaaatga attgaatatg aaaatagact ttagatatcc taagggtata
    76201 agttgggagt ttataactaa tagaattaat gaaattggaa aaaaagaaaa tttaatagtt
    76261 gatatatata aggatttaaa attactgtat gtaaaaccag atagtgaatt aataaataaa
    76321 ttatcaaatg catataaaca aggttttgga aaagaagccg aactttttac aaaaggagct
    76381 gcatcttatg caagagtgtt aaaaaatgga gttgcgtttg gacccacaat agagggggat
    76441 aatccaaatt cacatcaggc aaatgaaaat ataagtatag atacattata caaagcaata
    76501 gaagtatata tatatgcatt atatagcctg gcatttcaat aaaaatggag gaaataatac
    76561 tatgaaggat aaattacaag tactttctgg agcaatgatg atacctgtta tattacttgt
    76621 tgtagcagga gtatttatag gattagggtc agcttttgca aatatggaaa acgtttctgc
    76681 attagggctt agcggactaa taaaagaagg gtcatttata aatgtattct ttaaagtaat
    76741 aaacgattta ggatttatgg taatgagata cttaccaata ttctttgtta caggtatagc
    76801 ctttggatta tctaaaaagg aaaaaggatg gggtgcatta ggaggaattg ttttatttat
    76861 aggaatgcac acagttataa gtacattgtt agcagcaaat ggtataaatt cagatacagt
    76921 tacagcagaa gcgtttatgg catctggatt aggagaggca gaagcatata gtcgaagttc
    76981 tttatatggt tctttcttag gaatcttttc atatgattgt agtatatttg gagctataat
    77041 agctggattt gtagctagtg cagtacataa caaatttgtt gacatagaac ttcctagtgc
    77101 attatctttt ttctcaggtc caagattttc aatgattatg atgtttatag catcaatagt
    77161 attgggtaca gcaatgtact ttatatggcc accagtaggg ttggcattat ctaaacttgg
    77221 taattggata ggttctagtg gattattagg aacatttact tttggagcaa tggataaagc
    77281 attattacca tttggtatac atcacttaat tgcattccct atagaatata caagagtagg
    77341 tggaacaatg gaagtaggtg gagcaattta cgagggtgtt aataatataa gattagctca
    77401 aatgggagac ccagatacac tatcttatat aactcgtaac ttcacaacag gtcgtttatt
    77461 aatacatttt gcaatattac cagcagcagc tttagctatg tataagttgg ctgataatgc
    77521 taataagaaa aaagcaataa gtatattgat accagcaata gtaacagcca tgttggtagg
    77581 ggtaacggaa ccaatagagt atacattcct atttgttgca ccattattat attttgtagc
    77641 atatgtacca ctggcaggat tgacatatgt atttacagaa atgtttaatg tttctataat
    77701 gggagaatca tttagaaata tgtttcctaa tttattacaa ccacaaaaag tggatgcgtt
    77761 accattatta tttttgatac caatattttt tatagttact tatataatat ttacatgggc
    77821 aatcaagaag tttgatataa aaacaccagg aagaagttca gaagaagtta agctttatag
    77881 taagaaagaa tatagagaaa gacaatctgt agatgctggt aaaacagcat acaataatgc
    77941 agtagaagag gaagtagatg ataaagatac aaagcttgta cattctataa tagaaggttt
    78001 aggaggaagt aataatataa aaaatgttac aaactgtgca actagactta gggtagagct
    78061 aaattcaatt gatggattct atgaagatgg cttctgggta aatgaattgg gtgcaagtgg
    78121 agttgttaaa aagaaaaact cagttcaagt tatatttggt ccacgagtta ttacaatagc
    78181 atcaaagctt aaagctgtac ttggagtaga ttaatgtata taaagctatg taaattgata
    78241 agtttacata gcttttattt tttattataa aggtattata ataatttaaa atttgtggaa
    78301 agtttgtgtg tatttaaaat atactacagt atttaaatta tatggagaaa aaattatttg
    78361 tgaaaaatgg aatgaaatca taaagtaaga attattatac tgaaaatatt tacaatctcg
    78421 acatattatg ctacaattac tttgaattaa taaaaattaa taagaattac ctcatctaac
    78481 aaacagattg aggtagaggt tgcatttact aagattaata ttgaagaggt tggaaaccaa
    78541 tgaggcaata taaaaggagt aagtgccgaa gtgctagtgt ccgaagctag tgctgggact
    78601 gtatttaata ggtacagtac tgtcatcaaa attatcccga attttgatgg agagctatct
    78661 taaacaagat aaagggaaga tgcaggtatg ttgtatttag cacatttagc tcaacatgta
    78721 tccatgttga gcttttttac atctatacaa aataggataa agggatgcaa taataaaata
    78781 tttaatttaa aaagtgggga gattaaaaat gagcagttta aaaaagaaaa agtttactat
    78841 gccacagaca cttacaataa tatttttgct aatagtgtta atggcaattc ttacttggat
    78901 agtgccaagt ggaaattttg aaagagtaga tatagacgga aggtcagttg ttgtagctgg
    78961 aacttatgaa aaagcaccat caaatccaca aggaattact gatgtattta cagcacctat
    79021 aaacgggttt atagatgcag ctgaagtagt tggatttgtt ttaatagttg gaggagcttt
    79081 tgggatagtt aataaaacag gagctataga agctgttata gctcatactg taaataaaat
    79141 gaagaagttt caatttttaa taataccgat ttcaatgatt ctatttggac taggtgggac
    79201 gacatttgga atgagtgaag agacactacc tttttatatg atatttattc cacttatgac
    79261 cagtatggga tatgattcat tgacagcagt ggccacagta tttataggag caacagctgg
    79321 atttggagca gctactacga atcctttctc tgtaggaata gcacaagcat tatcacaaat
    79381 agcaccaggt tctggaatag agtttagagt tgttatgttt ataatatata tggctatatc
    79441 tataggattt gttatgatgt atgccaataa agttaaaaaa gaccctaaaa aatctttagt
    79501 acatgatata tcactaaatc aagaatcaat ggttaatagt gatacaaata taaaggaatt
    79561 tacaaaaaga gaagccatgg taatagcaat tttcacaata ggtatggcga ttatgatata
    79621 tggagtttta aagttgggat ggtatataac tgaaattgca atgatattta cagctatagg
    79681 tataatatca ggtatagcat caggtcttaa acaagatgat atagttaatt catttataag
    79741 tggagcagga gatttaatga cagcaggatt gtgtatagca tttgcacgtg gaattgtaat
    79801 aatagcagaa aatggattta taatagatac aattttaaat tctgcagcaa atttattaaa
    79861 tggattacca aaaactatat ttataaattt aactttctta atagaaggat taatagcatt
    79921 tttaatacca tcagcatcag ggcttgcatc acttacaata cctgtacttg caccacttgg
    79981 cgacttagta gatgtatcaa gacaaatgat agttacagct tatcaatttg gtataggtgt
    80041 aactaactta ataacaccta catcaggtgt tttaatggga gcactagcag tagccaatat
    80101 tccttggtca aagtgggtta gattcgtaat tcctttaatg gtagtattaa caattcttgt
    80161 aatggcattt ttgacaatag gattatatct aggattctag taggaggtaa attatgatag
    80221 agagtataaa gaagagagct tatgagatag agaatgaact tggaaaagaa attgaagaag
    80281 tttgtaattt tatatttaac aatcctgaat taggggaaga agaatacata tcatcaaaat
    80341 acttagtaga aaaaatgaag gaatatggat ttgatacagt ttatccatat tgtaatatgg
    80401 agactgcttt tagagctgaa ttgggagata atgatggacc taccatagca tttttagctg
    80461 agtatgatgc acttcctgga tatggagaaa ataaagaacc agctcatgct tgtggacata
    80521 actggattgc agcatctaca ataggagctt gtatagtatt aagtaagtta aaagaaaatt
    80581 ttaaaggaaa aattgtacta ataggaacac cagctgaaga aacaacagga ggaaaatgtg
    80641 atttagttaa ggcaggagct tttgatgatg ttgatgtaag ttatcaaatg catatagaag
    80701 cttttaataa tataaactgt aaggctttgg cgatagattc attagagttt agttttgaag
    80761 gggtatcagc acatgcagct agtcaccctc atatgggagt taatgcacta gatgcagtac
    80821 aacttacttt tgctgggata aatgcactaa gacaacatgt aaaatcagat gttagaatac
    80881 atggtatagt ttcaaatgga ggagaggctc caaatatagt tccagaaaaa gcagcctgta
    80941 agtttttcgt aagagctgct gaaagaagtt atttagatga agtaactaaa aaagttataa
    81001 actgtgcaaa aggtgcagag ttaatgacag gagctaagct ttcttataga tactttgaaa
    81061 attcttttga caacataata aataacaaag tacttcaaaa gataacaaag aataatttga
    81121 ttgaggcagg tataacagat atattagaag gtaaagatgg tccagtaggt tctacagata
    81181 taggtaatgt aagtcaagtt tgccctacta tgtatacaga aatagcctta gatataagtc
    81241 caatggtata tgttcatgaa aaagaatttc taaattatgc aaattctgag gaagcttatg
    81301 ataaacttca caaagcagta aaggcaatgg taggatgtgc attagaaatt tatttagaag
    81361 atggactact tgatgagatt aagaaaaacc acttaaatta aaaataaatg ggtattactt
    81421 aaagaaagta ataccttttt tattttgttt attgataaaa atagtacttt gaagattcaa
    81481 tttatataat ttatttaaaa ttaaaatatt gagaaaaagt tgacactaaa aaataaattt
    81541 gctaacatat aataaataat aattaaaata aaatacaaac ggatagtgat tgtttaaata
    81601 caagctaaac ctatttatta ctcaggactc atgggagtct atttaatgtg taataaatag
    81661 gttttttttt atgtaataaa ttacatttta aatattctaa ataattaaaa aagatttatt
    81721 ttaacttaat gctaataaag ggggcatcac aatgattatt gaaaaaatac tcaataataa
    81781 tgtaattatt acaactgatg aaaatcataa ggaaatagta gttatgggga gaggtttagc
    81841 ttataaaaaa cgtacaggag agcatatatc aaaggataaa attgataaga tattcaaact
    81901 ttcagaccca aatatatctg ataaatttaa agaactaata gcagatattc ctataagata
    81961 tatggaatta tcagatgaaa taattttata tgctaaagaa aaactaggga aaagattaaa
    82021 tgatagtatt tatatttctt taacagacca tatgtatact gcaatagaaa gagctcgtga
    82081 aggagtaagt gtaaaaaatg tattactttg ggatataaaa agattttata agagtgaatt
    82141 taaaataggg ttagaggcat tggattatat agaaaaaaaa tttgaaatta gactatcaga
    82201 agatgaagct ggatttatag cactgcatat agttaatgca caaatggatc aaagtataaa
    82261 aactatatat gagattacac aaataataca agaaatttca aatatggtta aataccatta
    82321 cagaatagta tttgatgaag attcagttta ttatcataga tttattactc acttaaagta
    82381 ttttgcagaa cgaattgtta gtaataattt acatgaaaat aatgaagatg atttattaaa
    82441 tgtaataaaa gttaaatata aaaatgctta taaattcata gaaaagttgg atgaatttat
    82501 acataaaaaa tacaactacg atttaacaga tgaggaaaaa ttatacttaa ctattcacgt
    82561 tgaaagagtg gtaagtaaaa gtattaagtc agatataaat cctaataatt aggtttatat
    82621 atattgggtg gtgacattaa gttggccaaa ccttcatatt tcaaaaagaa aatggaggag
    82681 aaaaaatgag aaagtatgaa caactatcaa aagaaatcat tgcgaatgta ggaggaaagg
    82741 ataatattag cagtttatct cactgtataa cgaggctacg ttttaaatta aaagatgagt
    82801 caatagcaaa tgatgatgtg ctaaaaaaaa tggatggtat agttactgta atgaaaagtg
    82861 caggtcaata ccaagtagtt attggtaatc atgttccaga tgtttatgaa gttgtgtgcg
    82921 atttggctgg attaggagga gatacaatag ataattcaga ttcagatgcg ccaaaaggat
    82981 tacttaataa gtttatagac ataatatcag gagtttttca accaatatta ggagttctgt
    83041 gtgctgctgg tatgataaaa ggatttaatg cagtatttac agcattgggt ttgtatggag
    83101 aaactgatgg tgcatatatt atgttaaatg caattggaga tgcaatgttc cagtatatgc
    83161 caataattct tggatataca gctgctaaga aattcaaatt aaaaccattt attggaatgc
    83221 ttataggtgc agttttatgc tattcaggta ttcaattaga tactctagca tctacaggtc
    83281 aacctttata caatctattt actggaacaa tatttgaatc accagtatat ataactttct
    83341 taggattacc agtaatagca atgaactaca cttcaacagt agtaccagta attttaatag
    83401 tattattagc agctaagttg gagaaagtgt ttgctaaaat aataccagat gtagtaaaga
    83461 atttctttgt accaatggca gttttattag tttctttacc attgggattt atggttatag
    83521 ggcctatagc tacctatgct tctaatatag ttggaaatgg atttttagct ttatttaact
    83581 tttcaccaat tttatgtggt gcattaactg gtttattgtg gcaagtgctt gtaatatttg
    83641 gtctacattg gggattagta ccaatagcta tgtcaaacct tatgactatg gggtttgaca
    83701 caatattagt gggagcattt gtaccatctt ttgcacaaac agcagtagta gcagcaatgt
    83761 actttaaatt aaaagataag aagataaaag agctgtgtat acctgcagtt atttcaggga
    83821 tatgtggtgt aacagagcct gcaatatatg gaataacttt accaagaaaa acaccattca
    83881 tatatagttg tgtaggtggt gctgtggcag gagctgtaat ggggataatg aatgtaaaaa
    83941 gttatgtaat gggtggactt ggaatatttg gtatacctaa ttatataaat ccaacaactg
    84001 gagatatgaa aggtgtttat gcaactataa tagcaataat agtagctatt gtagtaggat
    84061 ttgttttaac attatttttt tggaaagatg atgctatagt agaaatttct aaagatgata
    84121 atgggcaagg cgttatagaa aaaaacaaaa gagaagtagt atatagccca ataaaaggtg
    84181 aagtaaaggc tttggagcag atacaagatg cagcgttttc aacaggtata ttgggaaaag
    84241 gtgtagcaat aacacctaaa gaaggaaaag tagtggcacc atttgatggg actgtaatga
    84301 ctttatttcc aacaaaacat gcaataggaa ttatatctga taatggttgt gaactattga
    84361 tacatatagg gttaaatact attcagttgg aaggtaaata tttcaaatct tttgttaatc
    84421 aaggggataa gattaaaaaa ggtcagacat taataacttt tgacatagaa agtatttcaa
    84481 aagaaggata ttgcttagaa acaccagtag ttgttactaa ttattctgat tatgtggata
    84541 ttgtagaaaa tacacaaaag catgtaaata atagtcagga attgataact gttttagcgt
    84601 aaaagagagt tctattaatt aagaattata tatatgtatt tttattttaa aataaagtta
    84661 ctataaataa attattggag gtagaattat ggcacttaga aaagattttt tatggggtgg
    84721 agcaacagca gcaaatcaat gtgaaggtgg atataaagaa gatggtagag gtctagctaa
    84781 tgttgacgtt acaccgcaag gaaaagatag atttccagtt ttggctggga aaatgaaaat
    84841 gtttgaatgt gatgatgaac actattaccc agctcatgaa gcaatagata tgtatcacaa
    84901 ttataaagaa gatataaaat tatttgctga gatgggattt aaatgctatc gtatgtcaat
    84961 agcatggact aggatatttc caacaggagt tgaggatgtt ccaaatgaag agggactaaa
    85021 attctatgaa gatttatttg atgagtgttt aaagtatgga atagaaccag tagtaacaat
    85081 ctgtcatttt gatgttccca tgtatttggt aaaaaaatat ggagcatgga gaaatcgtaa
    85141 gctagtagac ttatatgtaa aatactgtga agttattttt acaaggttta aaggtaaggt
    85201 aaagtattgg ctaacattta atgaaataaa catgatactt catttaccat ttataggtgc
    85261 aggtctctat attgaagagg gagaaaatga agaacaaata aaataccaag ctgcacatca
    85321 tcaattagtt gcgagtgcgt tagttactaa actagcacat aacataaatc aagaatttaa
    85381 aatagggtgt atgctagcgg caggaaatac ttatcctaat acttgtaacc cactagatgt
    85441 atggaaatct atagaaaaag atagggaaaa ctactttttt atagatgtac agtctcgtgg
    85501 agaatatcca acatatgcat taaaagaatt ggagagaaaa ggaataaata tagtgatgga
    85561 agaagatgat aaaaagatac ttaaagagaa cacagtagat tttatttcgt tctcatatta
    85621 ctcatcaaga cttacaagtg cagacccaaa agtaaatatt ttaacagaag gaaatgtttt
    85681 tgcaagtctt aaaaatccat atctagatgc aagtgagtgg ggatggcaaa tagacccact
    85741 agggcttaga ataactatga actctttata tgaccgttat caaaaaccat tatttatagt
    85801 tgaaaatgga ctaggatcag tagataatcc agatgaaaat ggaaatataa atgatgatta
    85861 tagaattgat tacttacgtg ctcatataaa agccatgata gatgctgttg agttagatgg
    85921 tgttgattta tgggggtaca caccatgggg atgtattgac ttagtaagtg caagtactgg
    85981 agaaatgaag aagcgctatg gatttatata tgtggataaa gataatgatg gaaatggaac
    86041 tttaaaacgc agtaaaaaga agagttttgc ctggtataaa aaagtaatag aatcaaatgg
    86101 tgaagaatta taataggagg atataggtat gtcatttaaa aaagattttt tatggggtgg
    86161 agcaacagca gcaaatcaat gtgaaggagc atggaattta gatgggaaag gtccttcttg
    86221 ttcagatatg tgtactggag gttctcaaaa agtaagtaaa agaataacga gagttataga
    86281 aaaaggaaca ttttatccaa gtcatgaagc aatagatttt tatcacagat acaaagaaga
    86341 tatagcttta tttgcagaaa tgggatttaa ggtatttaga ttttcaatag catggactag
    86401 aatatttcca actggaatgg agaaagaacc aaatgaagca ggacttaaat tttatgaaaa
    86461 tgtgatagat gaatgtttaa aatataatat agaaccatta ataacaatat ctcactatga
    86521 aataccattt gcaataacag agaaatacaa tggatgggtt tcaagagatg taatagactt
    86581 gtatatgaat tactgtgaaa caatatttaa aagatataaa ggaaaagtaa aatattggct
    86641 gacatttaat gaaataaatt cagctacaat gcctatggga ggctacttat cacaaggaat
    86701 attaaatgaa gggactacag attttataaa ccaagtagat atacctcaac ttcgttttca
    86761 agggttacat catcaatttg tagcaagtgc taaggctgtt aagttagctc atgaaataga
    86821 ttcaaattat caagttggat gtatgcaaat atttgcaaca atgtatcctt atacttgtaa
    86881 tccagatgat gcagttaaaa ctcaaagaga tagtagagta atgaattatt tctgtggaga
    86941 tgtacaagtg cgtggcgaat atccaactta tatgaataga tattttggag aaaataatat
    87001 tgaaataaaa atggaaaaag gagatttaga aattttaaaa gaaggttgtg tagattttta
    87061 tacatttagt tattatatgt ctacatgtgt aagtagtgat tctaaagaag ataatacaag
    87121 tggcaacata ttaggtggag tgaaaaatcc atatcttaag tctagtgaat ggggatggca
    87181 aatagaccct gaagggctta gatatgcact aaatgaaatt tatgatagat atagaatacc
    87241 tatgatggta gttgaaaatg gtttaggagc ttatgataaa aaagaatcta atggagtgat
    87301 aaatgatgac tatcgtatag agtatttaaa agcacatata gagcaaatga aggaagctgt
    87361 agaagatggt gttgatttat ttggatatac tccatgggga tgtatagatt tagtaagtgc
    87421 atctactggt gagatggcca agagatatgg gtttatatac gtggataagt atgatgatgg
    87481 aagtggagac ttgtctagga ttaagaaaaa gagttttgac tggtataaac aagtaataga
    87541 atctaatggt gaaaggttat agtatgtaga tactgtttgt acttagaaga gtagtaaata
    87601 gtgtttatat atacaatttt ttattacaaa aaaggtggag tgacgaatcg ttattccatc
    87661 ttttttataa tgcatttaat gggtaaaagt gatatatgat ttgtacaatt aacctataaa
    87721 aatagattaa taatataaag acttataagc tataagtgct aagtctgtaa atactattga
    87781 ggaactttag aataaaatta agaaaattat taatttggca caatttttgc tttatagaag
    87841 tttaagaaat atgatagata ttgcaactat gatatttatg gacataaaac taataaagga
    87901 atatgttagt atactaaatg tacaattttt tgtgttatta aagtgaaaat caaatgtata
    87961 ttataaaaga gtagagtata ttttaaaagg agtaatcaaa tgaaaacaat agcagtagta
    88021 actgatgggt tgtctaaatt agaatgtttc ttaaataaaa atctagaaat gatatttaaa
    88081 gataaagtaa tgataaaaaa ttattattta aataaaataa cagagaagga attaataaaa
    88141 gatgacataa tattggtaat gatagatgat agagtattaa aaataaaaaa atatgtagaa
    88201 gatgtctcaa agataataac tataaatagg agcataaagc aaaaggatat atataagtta
    88261 ttttcattgc cagaaggaat agatgtatta gtagtaaacg ataataagca tactgtattg
    88321 gaaacaatat ctaatttata caatatagga ataaatcatt tgaattttat accatacaat
    88381 cccaatgaag aatatagaaa tattaagata gctataacgc caggagaggc aagtttagtt
    88441 ccaaaatata tagaagaagt tattgattta ggccataggt atattgatag ttcaacgttt
    88501 attcaaataa tagcaaaact caaactggat gataaagaaa ttactgagag gctaattaag
    88561 tatacagatg aaataattag tttatattca ggaataaata ctaaatacaa agaacttact
    88621 ataaaagcag atgaattaaa ttctataata aatttatcaa acttaggtat ggcaatggta
    88681 tcagataagg gaaacataat tatttgcaat aatagtttag gggatatact agatattcaa
    88741 agtaatatta tagggaaaaa tatagatgaa ttagagaatg agaatattaa aaagattttt
    88801 agtttgagta aggcacatga tgaagttata aaatttaata ataagtactt aaacgtaaat
    88861 aagtataata tagagagttt tggaagggtt actggatatt atttttgtat tcaagaaata
    88921 acttacataa gaaaattgga gcaaaaccta tcaaagaagc ttagagaaaa gggacaagtt
    88981 gctagatata cttttgatga tataaaaaca gtttcaacga agatggaaag aactaagaaa
    89041 ttaggtatga aaatagctga atctgattat acaattctta taacgggaga aagtggaacg
    89101 ggaaaagaac tcatggctca gtctattcat aatgcatcac caagacatag tcagccattt
    89161 atagcaataa actgtgcagc tatgccagaa aatttacttg aaagtgaact ttttggatat
    89221 gaagaaggtg cttttacagg agctttaaaa ggaggtaaaa aaggattatt tgaacaggct
    89281 aacaatggaa ctatattttt ggatgaaata ggagacatgc ctatatactt acaaagcaaa
    89341 ttacttagag tattacaaga gaatcaagta atgagggttg gaggagaaaa tgtaatagat
    89401 atagatgtta gagtaattgc ggctacaaat aaaaatttat tagaaatgat aaaaggagat
    89461 agatttagag cagatttata ctataggata aatgtattgc ccataaatat actaccttta
    89521 agagagcgaa aagaagatat agaagttatg ttaaagcatt ttatgaaaag gaagagagca
    89581 attagtcaag atgttcaaga cattattaat gcatatgaat ggccaggtaa tataagagaa
    89641 ttaaaaaata ctgctatgta tattaacatt atgagttctg aggatgttat tttaataaat
    89701 gatttacctc ataacttatt aaatataact gaagatttta gtaaagaaat aagtatatta
    89761 aaggatagaa catctataga gaaagtaaag ttagtaatgg agtgtttaaa aaatgccaat
    89821 aatcttaata aaaatatagg tagaaatggt attgttaatt caataaatga attaggctac
    89881 aatataacag aaggtgaggt aaggggaata cttaatatgt taaaagagct ggatttgata
    89941 atatgtgaat ctggtagaaa gggaagtgaa ttaaatagaa ggggaaaaaa tatattaaac
    90001 agtatttaat aggttgataa aaaggaaaat ctaaatgcct attttaccta ttagttgtac
    90061 ttaaaacaat ttaaaaaagt caaactaaac aggattaaaa taaaatataa gtaaataaag
    90121 ttatttatat tactcgtatt caaaaaaagt atttctaaaa taaattataa tgttcaaata
    90181 aataaaatct tggtatgcta cttgctcttt aagagaagta gcatttttta ttgttcacaa
    90241 ataagttaag gggtgaagaa attggttaaa aagaaatatc caataatagg aatatcaggt
    90301 aatttactaa ttgatgaagg aggaatgttt cctggctatg aaagggctta tgtaaataat
    90361 gattatatac aatcagtagt tatgtgtaaa gctataccat atattgtacc gattgtatat
    90421 gatgaggaga ttataaagga gcaggtatct aatatagatg cgcttatact atctggggga
    90481 caagatgtaa atccactcat atggaaagaa gaacctcata ataagttgga ggcaatatca
    90541 ccaaagagag atagttttga tatgaaatta ttaaaacatg ctttagatat gaaaaaacca
    90601 gttttaggta tatgtagagg agaacaaatt ataaatgtaa ctgaaggagg tagtttgtat
    90661 caagatttat ctttaattga aggtgcttat attaaacaca atcagaaaca tctatctaat
    90721 gtacctacac atacagtaca gataaaggag gggacaaaat tatatgaaat actaggagaa
    90781 aaagaagttt tagttaatag ttttcatcac ttagttgtca acaaagtagc accaggatat
    90841 attgtttcag ctacatctaa agacggttta attgaagcta tagaaaagga aggaagtgag
    90901 tttgtaatag ggatacaatg gcatccagaa atgatgacta gagattatga taatatgaaa
    90961 aaaatattta tggcaatagt taaagaagca tctaaataaa aaatataaat atattaagtt
    91021 ggctttgggg ggaataacaa tggaaaaagg cattaagtta ggtttttgga gtattgtact
    91081 attaggaatc aatgcaataa tagggtcagg tatattcggg ttacctggtg atgcttatac
    91141 agatataggt ccagcaagta tattagtatt agttttttgt atgcttttag ctgtttctat
    91201 tgctttatgt tttgctgaag caggtagttg gtttgatact gatggagggc cctatcttta
    91261 tgcaaaagag gcatttggag attttgttgg atttgaagtt ggatttatga agtggatagt
    91321 tagtatgatt gcttgggcta ctatggcaaa tttctttgct gtaacactat catctgtatg
    91381 gccacaagca gcagaaccac ttactaaaaa tataataatt ggtatattag ttgtaggact
    91441 tgggattata aattttatgg gaatgaaaca atctaagcac ttaaataata tcatgactat
    91501 aggaaaatta ttaccaatag ttttatttat agctgtagga ttattcttta taaagggttc
    91561 taattttacc ccatttgtaa taatacaaaa aggtcaaagt gcgtcatcag cttttgtagc
    91621 agtatctata actttatttt atgcttttac aggatttgaa tctttagctg ttgcagcaaa
    91681 agatatggag aaccctaaga aaaatgtacc taaagcattg gtaatggtaa tgtttgtagt
    91741 atcaataata tatatgctta tactgggaat aagtataggg gtgttgggta atggcttagc
    91801 agggtcagct actcctgttg cagatgctgc cattaagatg ctaggtccta taggtgggta
    91861 tataattaca ataggaacta tagtatctgt tggaggtata aatattgcat catccatatt
    91921 tacaccaagg tctgctgctg ctttggttga acaaggatta atgcctaagt ctataagaaa
    91981 aactaataaa aatggagctc cttatatagc aattatagta tctgtcatag gaattttact
    92041 aatagcatgg tcgggttcat tcacaacatt atctcaaata agtgttgtat ctagatttat
    92101 tcaatatatt cctacatgtt tagctgtact aatattgaga aagaagtatg ctggtaaagt
    92161 tgtaaatttt agaatacctg gaggagcaat tataccaata tttgcagtta ttataagtat
    92221 attattactg ataaaagcag gtattgatga acctatgaag atagtttggg gattaggtgg
    92281 gatgataatt gtagttccta tatatttcta tatgactaaa gtatattcaa agaaatataa
    92341 tgatgtagaa gtcaaataat tattgtaatc tatagatatt ctataaatat tactttgaat
    92401 ttagtaaaat cggtataaca ccagggtgtt ataccgattt ttacataaat aactttattt
    92461 ataatatatc attatacttt cgtaaggttt tatttccatt ttattttcaa ttatatctct
    92521 agtgtaattg gtttcaagta ttgtgtagtt taatttattc aaataagttt caggtaattt
    92581 atatactaca ttatcatgag taaaattact tataacaaga agattttggt ttttatactc
    92641 tctttcataa acaaatagat ttttatgatt ttcatctaac aatctataag taccttctgt
    92701 aaaaatatca tattgtttac gatatttgat taatctttga taagtataaa atactgaacg
    92761 agaatcatta agctcatttt ctacactaat attgtcatta ttaactttta accacggttt
    92821 atgattagaa aaccccttat aaatagtatt atcccattgc ataggagtac gggcattatc
    92881 tctggatttt tgttgaagta taagcaatgc ctccttttca tcaataccag atttaatcat
    92941 atgatagtat gcattcttac tttcagcatc atcatattca tctattttag taaagtaggc
    93001 atttgtcata cctatttctt caccttgata tatgtatgta gtaccctgta gaccaaatag
    93061 tgttatggct aacatcttag cactttcttg acgaaaaaat ctatcatctc caaatcgaga
    93121 taaagctcta ggttggtcgt gattagagta aaatagagca ttccatccct ttccttcata
    93181 cattttatat tgaaagtcag attgtgcttt ttttaattta tccagagaga acatttcatt
    93241 agtccatttt gcgcctcctt tataatctgt tttcatatga tggaagctaa aaaccataga
    93301 tagttcttct cgattttctc tagtatagtt gatacactct tcaggtgtag tagatgacat
    93361 ttcacctaca gtaactatat ttttaggttt gaaaactttt tgattcatat tatgtaaata
    93421 ttcgtgtata cgaggaccat cagcgtagtg agttcttcca tctccttttg gtcctgttat
    93481 agggtcatca ggtaatccag gtgttttgga gagtaggttg actacatcta aacgaaaacc
    93541 atcaatacct ttatcagccc aaaattctag tattttgtaa cattcttcac gaaccttttc
    93601 attttcccaa tttaaatcag cttgagtttc ttcaaataaa tgtaaataat attggttagt
    93661 ggtttcatca tatttccaag cagttccact aaatctggat atccagttat taggaacaga
    93721 accatcaggt ttagcatctt tccagaaata ataatcacga tatggattgt ctttgctttt
    93781 tttagattct ttaaaccatt tatgttcagt agatgtatgg tttaggacca tatccatcat
    93841 tatttttatg tctcttttat gagcttcttt taagagtttt tcaaagtcat tcattgtccc
    93901 atattttggg tctatattat aataatcttc tatatcatat ccattatctc tttgaggaga
    93961 aacgtacata ggagtcaacc ataataaatc aacacctaaa gaatacagat aatctaattt
    94021 ttctataata ccatttatat cacctatacc atcattgttg ctatctttga aactttttgg
    94081 atatatttga tagacagttg cttttttcca ccaatttttc atacttgata cctcctgtaa
    94141 tttataagtt aattataata tgtttaaaca aattgtcaag tattaaactg atattaaagc
    94201 taaaatatac aataaataat tatttgtata aacatataat tgtatataga atagtgaggt
    94261 tagtatggga taaagtgtct aaacgtaaaa aaattatgtt taattaaaca taattttttt
    94321 aatatctttg agtaacatcc atgaatacaa atgtttcagg tgtatgcttt gattcagtat
    94381 attcaaaaag ctttccatca tcagtatata cactattttt aataacacca acacaattat
    94441 aatcatttag aggtagcgtt tttaactcaa gctctgtagc tttttcaatt ttaaatatct
    94501 ttctggatga aacaattttt gtacctagac actcttctat atatttataa atagagcctt
    94561 gtgctataga aacatcaagg tctctaacta tactacatag aaaatagtta atgtcgagaa
    94621 ttttaggtat gttatcaata tatcttagtc tgtgaaggta atatacttca ctaccaactt
    94681 taaaacctgt ctttttagat aacttattat caattaagat tttgctgaag tggagaacac
    94741 tagtagcagt attaaccttt ttatcttcta caatcgattc tacacctttg aaattgtgca
    94801 tatttagaaa aaaatcatta gaacaactat tttctaacac tacaacaccc ttgcctttta
    94861 tactttgaac atatccttct gtgtttaatt gagaaattgc tctacgtaca gtgtttctgc
    94921 tacatgaaaa cctttcaata agttgaagtt cagtaggcag catcatatta cttgtatatt
    94981 taccatcaag tatttcctct ttcaatactt catatatctc tgaaaattta tttttagcca
    95041 tataccccta tccctcctta aaggtcttta gtaatattat tgaactgata tgaacaaatt
    95101 atatcaaatg tgtttagaca tgtatagtga aaatagaatc atatcaacca taaaaaggac
    95161 aaaatagaat tattttgtgg gttgtttcaa atacatggtt aaacatattt ttaaaataaa
    95221 aaaaatgaat taaaaaaata ggctagatat agcaatatac ttaaagggat ttatatgtta
    95281 aactaaatga taaaaataaa atgaataaaa aatattgaca atttgtttaa acaaatataa
    95341 tatttaaaat ataaaatgtg aataaatcgt tttcacaaaa aattaaaccg aaatagaaag
    95401 gggattggat atgaagaggt tcttaaacaa aatgatgcaa caactgtcac ttttaggaaa
    95461 gactatgctg gtgccaatag ctgtaatgcc agcagcaggt atattaggat tattatttgg
    95521 tccaaatatg ctcaatgtgc cagctatatc taatatatct aatatagtat tttcaaatgt
    95581 ggactactta tttttattag gagcagctag tgcctactca aagtctaaag acaagacaag
    95641 tgtaatggtt gcagccgtag ttgcatatat gatatttaag tcaaatttag agttattgaa
    95701 tgatacatta aatgcaggtg tatttggtgg gataattgtt ggagcttgta tagcatggac
    95761 ttacaataaa acatataaag ttaaagttcc agcattttta agcttctttg caggagaaaa
    95821 atgtgtaatt acactatcac cagtggttgc tttaatttta tcatatatat ttagtttatt
    95881 atggatatat ccacaagctg caatgaatca atttggtttt tggttgggag gagctggtgc
    95941 aataggaata ttcttgtttt tattctgtaa ccgtgcacta ataccaactg ggttacatca
    96001 agttttaaat gcttacatat tatttgaaat gggtgaatat acaacatcaa caggagaagt
    96061 tataagagga gaaattccta gatttatggc aggagaccca aatgcaggat tcttctggac
    96121 aggattttac ataattatga tgttttcaat acctgctatt tcttatgcta tatataaaac
    96181 agcacaagat aaaaagaagc aagaagtaaa aggtgcaatg accgctggag cattgacttc
    96241 ttttatggca acagtaactg aaccaataga attttcgttt ttatttgcat ctccaaagtt
    96301 atatataatt cattcttttt attctggtct aggtggagtt gtactatatt tactgggtgc
    96361 tcgcttgggt tcatttaatg gagcaagtat aattgactat gtcttaagtt ttagttatgg
    96421 agataaagcg tggttagtta tacctgtagg agttgtattc tttgtattat attatgtaac
    96481 atttaaatat ataataataa aagataatgt gcaaacacca ggacgtgaag ttgagataga
    96541 gataggtgat aaagttagtg aaaaagaaaa gaatttaaaa ctttctcatg gtaatttttc
    96601 atatatggct aaacagataa ttaaaaattg tggtggttat gaaaatatag tgactcttaa
    96661 taattgtatg acgagattac gtttagaagt gaaggatgcc actattttga atgatgataa
    96721 tattaaaaaa acaggagcca aaggggtaat taaattgagt aatacatcag ttcaaatcat
    96781 cataggaacg gatgttgtta aagtaaagga tgagatggaa atgcaacttg atgagttgag
    96841 aaagcaggca gatgcataaa atgaagaaat tagtagttag ggcagatgat ataggatatt
    96901 cagaaggtgt tacactaggg ataatatctt cttataagaa cggtattgtt acaagtgctg
    96961 gaatcatggt gaatatgcct ttttcaagac aagctataga aatggtaaaa aatgatgatg
    97021 tatgttttgg tttacatgtt aatttagtaa taggagaacc ttgttgcaaa gaacatatta
    97081 agataaagaa tttgttagat gaaggtggaa aatttgtttc tagcaaaata agaagaacac
    97141 aactactgac aggtaaagag gtttttaatt atgaagaagt atatgaagaa gtttgtgctc
    97201 aaattgaaac ttacaagttg tatatgagta aattgcctga atatattgat atacatggta
    97261 tagaagaaga tgtatcaata tcagcaatgt gtgatgctgc aaaagaatac ggtataccaa
    97321 gttgtcccta ttatttagat tcgtgtatta gcatgccaag taaatatcct cagaatgatt
    97381 tttacaagtt aaataaatct tttgttaaat tatttgaaga aaaatatata aatttagata
    97441 aagatataac attgatggtt actcatccag gatttataga ttatagtctt ataaaatcat
    97501 cttctcttat tcaagagaga gtatatgaac atgcaatgct atgtgataag gaagttaaaa
    97561 tgtggttaaa aagaaataat attgaattgg ttgattttaa agatattttc aagtctaata
    97621 attatatata aagaatagat tacctaaagt tttaattaaa aataagtatt tgaaaaaaat
    97681 gtgtattttc taaaaaaata ttgatagaga tgtatcaaaa taaaaacttg aataatctct
    97741 atcaatatag gaagtacaca ttttttatgt ataataaaaa gagtagtatg cattaataaa
    97801 ttaaaaatat taaattataa ttatattaac gaaaatttta gctaatattt ttgaatttta
    97861 cttatgaata ataaaataga tggaggagaa actatggaat tttatgaaag agcaaaaaaa
    97921 tatgagtata aatttacaga tacagaagac atgataattg aatatatgag aaaaaacaaa
    97981 gaagaaatag taaaattatc aatacaatct ttagcagata aattttttac tgtcccaaat
    98041 accatagtta ggctatgtaa aaaaatggag tatgatggtt tctctcaact aaaaaataat
    98101 ttaaaagaag agttaaaaaa tgaggataaa gagccaaaaa atggttttga atcagatata
    98161 aaaaagacat tagagctaat agattatgaa aaaataaata aagtagcaga tataattcaa
    98221 aaatctagga gtattatagt ttatggaata ggtcaaaaca ttcctttatg tgagatatta
    98281 gtaaaagaaa ttagaggtgg gcatgataat ataacttact atagtcaaag acatgaagta
    98341 cttcatgata taggaaaatt aggtgaacaa gatatgtttt ttgcacttag tttaagtgga
    98401 gaaacgaaag aagttataga agtagcaaag acagcagtta ataagggttg taaggtagta
    98461 gctttaacac atatatgtga aaatcaattg caacaaattg cagatataag tttatattgc
    98521 tattcaacaa ttaaacaagt aaatgggtac aatatatcag ataaggttcc aattatgatg
    98581 attatgagag caataataga gcagtactgg ttaagataga gatttgtgta taaatacaca
    98641 aatctttatt ttttaagaag aaattgtgtg tataatttca aaaaaacatt ttcataattt
    98701 attttatgct atattcatag cattaaatga tttaaggagg gcgtaatttt ggaatttaag
    98761 aaaatcacaa atgaaaacct tgttttttta aaacaaaaaa taaaaacaaa ggaagacgca
    98821 ataaagttct tagcaagaaa gctatatgat gaaggcaagt taacatctta tgaggaatat
    98881 ttagaagctg taatgtacag agaaacttta tctccaacag gttttgaaag agggcttgca
    98941 attcctcatg gaaaatctaa gtcagttaaa gaagctgcat ttgcagctat gaccttagag
    99001 acaccaatag aaaattggga aagcgtagac ccaaataata aagtagagct aatattttta
    99061 atagcagtac cagaaaataa aggtggaaat acacacatac aaatactttc tgagttagtt
    99121 actagactgt caaatgaaga ttatatgaat atgttgttaa attcaaaaac taagaaagag
    99181 ttatttaata acttagatat aaaagaaaag aaagaacaaa taaaagaaga gattaggatt
    99241 caaaatgaat caaaaaaaat tgtattagca ataacagcat gccctgcagg tatagcacat
    99301 acatatatgt cagcagaagc attaattaaa gctggtaaag aaatcggtgt ggatgtgtat
    99361 gtagaaaagc aaggagctaa tggtatggtg gaccctcata caccagatat aataaaaagg
    99421 gcagatgcaa taatatatgc aacagatgta gcacctaaaa atacagaaag atttgaacat
    99481 ttgccaaaca taaaaacgtc agtagcagct ccactaaaaa gagcaaaaga aataatatac
    99541 gaagctttag aagtagcaca aaaacaaggt aaaggtgatt atatagaaaa atcatctgat
    99601 atatcatatt gtgaaaaatc atcatggaaa aaagatgtaa aatcagcaat acttacagga
    99661 gtatctcata taataccact tattgtggca ggaggtatga tacttgcatt tgcagtatta
    99721 gcatctcaag catttggtct acaagaacta tacaatcaag aaggttcttg gttatggcaa
    99781 ttaagaaagc tttctggagg tatgttaggt acattgatgg ttccagtatt atcagcatat
    99841 atgtcttact cactagctga aaaaccaggt cttggaccag gatttgcagc aggtctagca
    99901 gctgatttaa taggtagtgg atttcttgga ggtatgttag gaggtttact tgctggttat
    99961 atagtaaaat ttttaaagaa gaatatacca gccaaaggca cattagctgg attcgtaagt
   100021 ttttgggtat atccagtagt tggttctttg gtagtaggtt tattgatgtt atttgtagta
   100081 ggaaagcctg tagcagcact taacaatagt cttataaatt ggttaaatgg gatgactgga
   100141 gtaaatgcaa tactactagg tgcaataata ggagctatgg tttcatttga cttaggtgga
   100201 ccaataaata aagcagccta tacatttgca ataggagcaa tagcaagtgg aaattttata
   100261 ccttatgcaa tatttgcatc agttaagatg gtttcagctt ttggagttac aatagctact
   100321 gttttaggca gagatttatt ttcagaatca gaaaaggaaa taggaaagca aacttggata
   100381 ttaggattgg ctggaataac tgaaggtgca ataccattta tgatagagga cccaatccgt
   100441 gttataccat cattggtagc tggttcagcc ataactgggt ctatagtagc attcttcaat
   100501 ataggtcttc aagtgcctgg agcggggata ttctcattgg cgcttttaga gggaagtatg
   100561 tcaggattta ttatagcatc aatatggttc tttgcggcag tacttggagc tataatatca
   100621 gcaatattat taataataac taggaaacaa aaaaatcaaa gaaagataca ttaaaagata
   100681 cgttattaga tatttaaatc aaaggtttaa ttatagtgat aaaataaata ttaaaaaatt
   100741 ttgtaaactc agtagtattt ttattggatt tttaattaga cagaaaatat tatcagataa
   100801 gttttggagg ataagcaatg aaaaaaaatg tacacatagt tcctcatatg cattgggata
   100861 gagaatggta cttctcaact gaggaatcta gaatattact tgtaaataat atggaagaaa
   100921 taatggatat gttagaaaat aatcataact atccatatta tgtgatggat ggtcaaactg
   100981 ctatattaga agattattta gcagttaagc ctgaatgtaa ggagagaata aaaaaattag
   101041 ttcaagaagg aaggctaata ataggtcctt ggtatactca aactgatgaa atggtagttg
   101101 gtggagaatc catacttaga aatttactat atggaataaa agattgtgat gaatttggag
   101161 aatatatgaa aataggatat ttaccagatt catttggtca aagtgctcaa atgccacaaa
   101221 tactaaatgg gtttgatata aaatactcaa tgttttggag aggatgttct gaaagaaaag
   101281 ggactaataa aacagagttt aattggaaga gtgatgaggg gtcttctgtt ttggttcaaa
   101341 tacttccatt aggttatgca ataggaaaat atctaccaat gaatgaagat gagctaagaa
   101401 caagaatgga taaatattta ccggttcttg ataagggtgc aactactgac catataatac
   101461 ttccaaatgg acatgaccaa atgccaattc aaaagaatat atttgaagtt atatataaat
   101521 taaaagaatg ttatccagag agaaaatttt tcttaagtag atatgaaaac atatttaaag
   101581 agctagaaaa aaatgaggat atagatacaa taaaagggga atttttagat gggaaatata
   101641 tgagggttca tagaagtata ttctcaacaa gaatggatat aaaatcagca aatgctagaa
   101701 tagaatcaaa gataaccaac atattggagc cactagcttc tattgcatat tctctaggat
   101761 ttgaatatca tcatggatta atagagttaa tttggaaaga aataatgaaa aatcatgctc
   101821 atgacagcat tggatgttgt tgttcagata aagttcacca ggaaataatg aatagatttt
   101881 tcttagctga ggaaaaagta gaccaattaa taacatttta caaaagaaga atagttgatg
   101941 caatgagttg tgaaatggct ttagataagt tagtagcatt taacttaatg ccttacgata
   102001 ggaatgaaat agtgagcgcc caagttataa ctaaaatgaa agcatttgaa atatttgata
   102061 aagataataa taagttggat tttgaagtgg tacataaaga agtaatagat gcaggattaa
   102121 tagaccgtca aattgttcat tatggaaact atgattcatt tatggtatat acaataaact
   102181 ttaaagataa aatacctgca atggggtata aggcgtatat gataaaagaa gttgaacata
   102241 tgttagaaaa agcttatgaa gtatgtgaca tggtagataa tgacttttat actattcaag
   102301 ttaatgaaaa cgggacatta aagatatttg ataaaaaatt aaataaaact tttgaaaatg
   102361 tattattgat ggaaaatgga ggagatgaag gagatgagta tgatttttca ccacttccaa
   102421 atgagaaatt aatatttaac gataatatag tagcaaattc cactataaag aaaaatagat
   102481 ttaataatga gataaagata aattatagat taaaagtacc aaaagatata caagctagaa
   102541 aaaataatag agcagattca tttattgact ttgatatagt tataaatgtt ccaaatgata
   102601 aagctataat agatgtagta ttcaacataa ataaccaagc aagagattgt agggttagaa
   102661 cttatatacc aacaaatata gcttcaaagt tttctgtgtc tgataatcag tttggacata
   102721 taaagagaag tgtgtatgat gatgctatgg aagtttggca acaggaagaa tggagtgaaa
   102781 gaccagattc tatatatcca atgctaacat tcgttggatt gtctgacaaa gagcatggag
   102841 tagctgttct tacaaacagt acaagagagt ttgaaatagt aggggaaaaa tttgacacaa
   102901 tagctataac attatttaga agtgtaggat tcctaggtaa agaagaaatg gcaagacgcc
   102961 caggtcgtcc atcaggaata aagttgccta ctccagattc tcaaatgata ggagatataa
   103021 aaatagactt agcaatagtt actcatgaaa aatctacact agaagcaaat gttgcaaata
   103081 tggctaaaga gtatttaaca aaaatacaaa cttataataa aatgccatat aatgctatga
   103141 aattgaatca atcagaaata gaagtagatt attcatatag tttacttaag gaaactaata
   103201 aggaccttgt gttaagtgtt gtaaaaaagg ctgaaaaaca agaggcatta gtagttagat
   103261 tttacaattc taaagaagaa acaaaatcag ctaacatagt atttaacaaa aatattaaaa
   103321 tagctaaatg gattaaccta aatgaaaaag aattagaatc tatatcaata gataataact
   103381 ctgtaaatgt agagtgctta atgaaccaag ttaaaactat attggttaaa tagtgctaaa
   103441 aatgattaga tagtgctaaa aaggaattat cttaaaatag agataatcct ccttatcatt
   103501 gttgaaataa taaacatata tttgatttta tacaaaaaga gtgtctcatg aactaagaaa
   103561 tttattttga gacactccct ttttataaga taaaagaata ttaatggtat aagttgtata
   103621 caaagagaga tatagagtat aaaataaaag ataaattaag cttataaaat tatatgttta
   103681 aaataaggag taataaaaag gagtagataa atatgaaaat attaatttct atagattctt
   103741 tgaaaggaag cttatcttca atagaggcag gaaatgcaat aaaaaagggg atattgaagg
   103801 ttaaagaaga tgcgcaagta aagatattgc cacttgctga tggtggtgaa gggacagtag
   103861 atgctttagt tcaagggatg aatggtaaaa aagagactat agaagttact ggaccaatag
   103921 ctaaaaaagt ggatgcaaca tatggattat taaaaaatac aagtacagca ataatagaaa
   103981 tagctcaagc atcaggatta acattggttc cgactgaact tagaaatcct ttatacacta
   104041 caacttatgg tgttggggaa ataataaagg aagcaataaa taaaggctat agaaatttta
   104101 tagttggaat aggtggaagt gctactaatg atgctgggat aggtatgctt caagccttag
   104161 ggtttgagtt ttatgatgaa aataacaagt tagtaggatt aggtggaaaa gttttaaatg
   104221 aaataagaca tataaaaata gaaaatagat taaaggaatt agatgaatgt aagtttaaaa
   104281 tagcctgtga tgtaaataat ccgctgtttg ggaaaaatgg agctgcatac atatacgggt
   104341 ctcaaaaagg tgcaacatca gaaataattg aggagttaga taatgggctt agaaattttt
   104401 ccaaagtagt taaaaattac ttaagtaaag atgtagctaa tgtagaagga gcaggagcag
   104461 caggaggatt aggttttgct tttttagcat ttttaaattc aaaattagaa tctggaataa
   104521 aaataatatt agaagaaatt aaattagagg aagagttaaa agatgcagat tttgtcataa
   104581 ctggtgaagg tagattggac aatcaaactg ctatgggcaa ggctccaata ggagttgcaa
   104641 aactggcaaa aaaatatggg gtaaaagtaa taggtttggc tggagccaca acagaagatg
   104701 cagttaaatg taatgaagag ggtatagatg cttatttttc tatagtaaat agagctatga
   104761 caatagaaga agcaatggat aaagcaactg ctagtgagaa tatgacatct acaacaacac
   104821 aaatattcaa tcttataact agtatacaac agtaaaaaaa tatgtagtat taaaacaagg
   104881 tatattaggt aaaaagctgt cacatattaa tttagacttt ttagtgtgac agcttatcta
   104941 ttttatgtta ataacttaag aaacatatat tggaaataaa ttaattgatt tagatatttt
   105001 gaataagata agctattcta ttcataaaac tactatagtt atctgcctta gtaagttctt
   105061 taacattatt ccactcagat aatatttcaa taaagctttc aaatatgtaa ttgaattttt
   105121 ctttttcttt ttcatttata ggtatcatag ctataatttg aactttttcc tcaccccatt
   105181 taactgattt atcgttaaca attaaacata ctccagtttt taaagcatcc attttcatgc
   105241 tatgaggaat tgctacattg ttattaaatg cagttgaaga cattttttct cttataagaa
   105301 catcatctat ataattgggt ttgacatatt tattttcgta cagaatattt cccataaatt
   105361 ttatataatc tttagcacta tctaaatata tatttttcat aaacaaagat tcactaaagt
   105421 acatttctaa atgattttgt acagtaagta tattttttct atctttaatc tgaataaatt
   105481 tactctgaat attatcataa tcctttctat ttaggtaagg atttacataa acaaaaggta
   105541 tagggcatct attgttaatt ggtaaagtag taataaccat gtctacctta ttgtcaaaat
   105601 caagattatg agtatctgaa aaaatctgaa taatttctat ggattcatta aatctcttct
   105661 cgaggtctct tactattttg aattgtaaat catagtaatt tggagtaatt aatgcacata
   105721 gaactttatc ttctaataat ttttgtctat caaagaatga acctacatga agagatatat
   105781 aagatatttc atcttcgtct atatctacac tttctaaagt ttgaatctga ttgcaaatat
   105841 aaacagatat atcatatatc aaagggtagg aatcttttaa cttttgaggt atttgatttc
   105901 ttaaaacttg attatttttg gctctactga ttaaattttt tacatgaaga gtaaatttta
   105961 caacaaattc ctcatcagat aaatctataa gatataagtc atatacattt ttaattattt
   106021 ttttagttaa tttaacaaag tgttcatcta tataatttga caatgattta gtatccattt
   106081 gattgtagtt taagactgta gttttgtttg ttaactgaaa tactaaatag tataattccg
   106141 cactagttaa agttatattg tattcagatt ctaaaaaatt tgatatgtct tttgcaatat
   106201 ttatatctac gttattgtct atgtagttta ctacttcaac agagtctatg taattattct
   106261 tttttattct gtctatagtt atcattaaat gaagaagtat gttgtttata gcatactcat
   106321 ttataaataa attgtatttt tttaatatat atattatatt ttcttttagt ttagtcaaat
   106381 tatactcttg atatattttt tgtacatcaa ataagcttaa aaaatcactt cccgtttctt
   106441 taaatattat agagctcatt aacttgcgct ttgcagattc atttccaatt agtttcaata
   106501 aaaatttcga ttgctttatc tttaaattat aacttcctat aaatttatta gctttgacta
   106561 tatccccttc aatagtagct gggctaacaa acaattcttc acttaaatca aatatattaa
   106621 ttccattact attaactata agttctttta aaattaaatt taacctgtta tcaggtgata
   106681 tattttctga actatcaacc ttggtttgac aattattatt gagatttact ttatatcctt
   106741 ttttagagga taatataaat tcaccattgg aattaatttc gtttacatat tttctaattg
   106801 aacgcgttga gacattaaga taattagcca atgtagatga atctatccaa tcatgttgcg
   106861 tttttatgaa gtttaaaaat aactcttttt tagatgtttt cattagattc cctctcatag
   106921 ttttaaaata aaatctgtat gatatgatat ttatataatt gaatgtacgt attataatgt
   106981 acattatact atatatttat gtgtctggtt aagagtaaat gatttcctat tattaggaaa
   107041 tatatttatg tgaaaggaaa ttatttagga agtacaatat aaatacaatc aaatcaaata
   107101 aaaattcatt aagaaataaa ttaatggata aaaatactgg aggtattgtt atgaagaata
   107161 taaaagtgtt gttggcatgt ggctcaggag caagtacagg ttttatggca actagtatga
   107221 gaaagagtgc aaagaaaaaa ggcatagaag cagatataaa agctagaagt gagtcagaga
   107281 tagataaata tttaccagaa atagattgtt tattattagg accacattta gattatatga
   107341 aagatgaaat acaaaaaaaa gctgatgaat ataatgttcc agtagcatgt atatctaaaa
   107401 cagcatatgg aagattagat ggtgtaaagg ctttagaaga agcattagaa ttaatattaa
   107461 acaaataaaa tatctatggg gagattgttt atgaataaat ttatagattt gttaagtgaa
   107521 aagtttactc ctgttgtaaa taagataact aagaatatat gggtacaatc agttcaatca
   107581 actataatga aagttttgcc tatggtattt gtaggttctt tagtaactat agtttctgtc
   107641 ttgaagaatt acataagttt cttacctgat ttaagtccaa taaatcaata tacatttgga
   107701 cttttaggac tatttatagc atttttatta cctatggaaa taatgaagaa taagaaattt
   107761 gaaagtatga gtgtagtagc tggtcttgca ggtgctggat taatgttaat gatgattcgt
   107821 ccagagatta cgaatgaagg agctatattt aacttcaata gatttggagg agaaggaatg
   107881 cttgtagcac tagttgcagg attattctcc ggattaataa tgtctttatt tgggtctttc
   107941 tcattttttg gtgaagattc agcacttcct gattttgtaa gtaagtggtt tgatagtatg
   108001 ttacctatag cagtaataat gtttataggt tggggactaa tttatggact taactttgat
   108061 atgtttgaaa taatagttag gatatttaaa ccagtatcag atatagcaca aacattgcct
   108121 ggatttgtac tattaaactt cttagtagta tttttatatt ctttaggtat aagtggatgg
   108181 gtattatccc caataactta tgcaattcag cttagtgcaa ttgcagctaa tgcagcagct
   108241 gtagcatcag gagggcttgc aactaatata tatacttatg aagttgttca aacaggttgg
   108301 ataactttag gtgggtgggg agcaacatta ccactagtgc taatgatgtg tttatctaga
   108361 gctggaagaa taaaagcaat cggaagagcc tgtatcgttc cttctataat gaacataaat
   108421 gaaccagtaa tgtttggagc tccagtagca tggaacccat ttttaatgtt acctatgtgg
   108481 ataggaacag tagtaatatc aataactact tacttatcaa tgagtatggg atttgtgaca
   108541 attccgagta aggtgtttaa tttatggtat gttccatttg gtatatctac ttttatggta
   108601 aatcaagatg ttagagggct tattgtttta gcaataaata tagtattgct atttatgata
   108661 tggtatccat tttttaaagc ttatgagaaa gaagaactaa aattagagag tcaagaggtt
   108721 taaatttaga tgttgaaagg aaattataaa tatgacaatt gaagaacata taatagatga
   108781 agaattagta gaagtagcaa tgcaaataat acttcgtgca ggtgaggcta gaacagaaat
   108841 taaacatgct cttaatgatt tggaaaagtt tgattataga aatgctgatt taaaactagc
   108901 taaagcaaaa gggtttatga cagaagcaca tagagctcaa accaagatta tacaagggga
   108961 agctggtgga gagaaaagag cacattcgct gttatttgca catgctcaag atactcttat
   109021 gaccatattc agcgagttaa atataactat gtctttagta ggaatagtaa agtctataga
   109081 atataaggta aataatagta aatgatttaa ataaataaaa taaggagtga ttaaattgag
   109141 taagtttcct aaaggttttt tatggggagg agctgtagca gctaatcaat tagaaggtgc
   109201 atggaatgaa ggtagcaaag gttggtgttt agctgatgta catatgtatg ataaagatag
   109261 agatatatct aaaccttatg agtctgatat gactatagaa agaataaagt ttgctatgaa
   109321 agataataat ggatattatc ctaagcgtag tggaatagac ttttatcata catacaaaga
   109381 agatttaaag cttttgaaag agctagggtt aaagtgtttt agattttcaa taaattgggc
   109441 tagaatattt ccaaatggag atgatttaga gcctaatgaa gagggattaa agttttatga
   109501 taatcttata aatgaagtaa tagataatgg tatggaacct attgtaacac tacttcacta
   109561 tgagactcct ttgaatttag tattaaaata taaaggatgg tctaatagaa aagtggtaga
   109621 tttctttgtt agatatgcag aattaatatt aaatagatac aaagataaag ttaaatattg
   109681 gatagttata aatcaaataa atttaatgta tcatgaatca tttaattcag ttgcattttg
   109741 tgtagaccag gtagatgatg tagaagaggc caaatatcaa gctattcatc atcaattcat
   109801 ggctacagct ttaactaaga agcttggaaa agaaataaat tcagatatga tgatagggat
   109861 gatgatggca gattgtacat cttatccaga agattgcgac cctgaaaatg tggtgtttgc
   109921 tttaaaaaga aatagaatac aatatttttt cactgatgta agttttaggg gagagtatcc
   109981 agtctatatt aagagatttt tcaaagaaaa taacataaat atagttatag aggaaggaga
   110041 tgataaaatc ttaaaagaaa atactatgga ttttctagct ttatcatact attattctac
   110101 aacagtatca gcaagtaaaa acaccatgaa tccaactgat aatataaaga atccatattt
   110161 aaaagcaaat ccttgggggt gggcaattga tcctaaagga ttatacaata ctttatctca
   110221 atattatgat agataccaaa agccaataat gatagctgaa aatggatttg gaatgcatga
   110281 taaatttgaa gatggaaaag ttcatgataa ttatagaata gattatttag gaaaacatat
   110341 agaacaaata ggtgaagcta tagctgatgg aaccgaaata ttagcttatt gtatgtggtc
   110401 gccaatagat atagtaagtt gttcatctca agaaatggaa aaaagatacg gatttatata
   110461 tgtagatata gataacaatg gaaatggaag taaaaaacgt tataaaaaag atagttttta
   110521 ttggtatcaa aatgtaataa gaactaatgg agaagaatta aaagaaaagt aaatagtttt
   110581 taaatataaa taatccctct tataaatact atgttattaa tacagtttta taagagggat
   110641 tataattata aataaggtgg tttattaatt atgaatgtca taaaaaaatt tatatttgta
   110701 attttaatta taaatatact gggatgtggt atatctctta tactccagtc aagccttggt
   110761 agtgatgcaa ttacactttt aaatgagggt atacatataa agttaggtat aagttataca
   110821 atagcagggc taatatataa tggaactcta ttacttatag cattgctatt gaataaaaaa
   110881 agtttgggat taggaagctg tgtttatgta ctagtagcag gaatatttat agatttgtat
   110941 atatacttat tattagattt taatataagt agtttaggga ttatcattag aataatgagc
   111001 tttataattg gacatatact tatgtgtagt ggatttgcaa tgcttataaa atttgacatt
   111061 ggaatgagcc ctttagatgc tatattaatc tatattgagg gcaaatttaa gtatccatat
   111121 aaagttttaa aaactatagc agatgtaata tttttaattt taggtgtata tttaggcgga
   111181 aatttagggt ttggaactat attttcaata ttatgtactg gaactacaat ttcaattgtt
   111241 agtaagatga tttctgttaa taaaaaaagg tattactcaa atatataaat tgataagtga
   111301 gagtatggat aatgtttatg aatcattttc aataattcga gttaatttga ggtcgtaaaa
   111361 attggagtta ctcagtttca gtaattgagt aactccaatt tttattacaa aatactctaa
   111421 taattatata attaattgaa gcataaaatt attatattat aaatttacat atatagacat
   111481 tgactaaatc ttaattgtat ataaaaataa gtagttaaga ggtaatatat tatattactc
   111541 gataaattta gacaaataaa acttatataa ggggagataa catatgataa ttgagctaaa
   111601 caaaagtaat tctgaaaatc taacgaagac ggaacttgaa ataattaaat ttataaatga
   111661 aaatgaatca atattaccag aattatctat agtagagatt gctcatgaaa catattcatc
   111721 tccagcaacc gtttcaagag caattagaaa atgtggttta aatggattca atgaacttag
   111781 gtatagatta acagtaaaag atgaaaatga tgatatacaa aatatggggg atataataaa
   111841 taaatccttt atagaagcac agagagttat agaacaaata tctttaacta cactaatcaa
   111901 tataataaaa actataaata aatctagtaa gatatatatt ttagcaagag ggcttactga
   111961 atatgtagca aaagagttta gtcttaaatt gcaattactt gattttaatg ttgtttttat
   112021 aaatgacccc aacataatga aaataaaatc taaatcaata aaaaaagatg aacttataat
   112081 tatattttca ttgaatggaa ataccataga gcttgtagaa tcagcacaga atgccaattt
   112141 agttggagct aaggttataa cttgctgttg tagtgaaagt gcaaaactta taaagtattc
   112201 ggatttatat attgtaggat acaaacatga acatatatca atttctgaat atgaagtatc
   112261 ttccagattg cccttgtata ttatatctag gataattata gattatatgg tcagatataa
   112321 taattctgaa aattaaattg aaaagtctat gaaaatcgat tttctatttg tgaaaagatt
   112381 ttcatagact tttttattat aatgaaaaca tacacagcac aagcaagggg gaagacaatg
   112441 atatatacat taactacgaa tcctgcaata gatatgaata tatctactaa tgggataaag
   112501 agaaaattag taaatcgtac atcaaatgct gtatattctc ctaatggaaa gggattaaat
   112561 gtaacttttg tactaggtca ttatggtata gaatctaaga tattaggatt ttttggagga
   112621 ttttcaggaa aatatatagt tgaagaaagc gaaaagagag gatttgacgt attgcctact
   112681 tgggtagaag atacaactcg tataaatata tttttaaatg atggaagtga tgaatttaaa
   112741 tttgtaaact ctgggtcata tgtaaacgaa aaacaaaaac tagatatgct agataagata
   112801 cagtcattag aagatataag ttacttatca ataagtggaa gtctacctcc tggtattgat
   112861 gataattact atgaggatat atttaaaatt tgtgaaaata aaagtataaa gacaatactc
   112921 gatataagtt caccaaaatt aaaggagtta ctacagtata atccatattt gataaaacca
   112981 aatgatgaag aaatcaaaga tatatttgga attattgtaa gagatgaaga agatattaag
   113041 gatgtactta aattactaca tttaaaaggt gctcaaaata tattgctaac tttaggagaa
   113101 aaaggttctt atttttataa tggaaaatca atttattatg ctagtgctca accagttaca
   113161 gtagtcagct ctgcatgtgc tggtgattct gcattagctg cttttttaag tatatggctg
   113221 gaaaatccag aacatattga agaagcatta aaaaggtcag cagcaacagg agcaagtgtg
   113281 gctgaaagta atggtatagg taatttggag aatgtggaag attatataaa aaatataaga
   113341 gtcagaaagg tggtataaaa atgggaaaga aaatgattct aggggtaaca ggttgtccaa
   113401 ctggaatagc tcatactttt atggcagaag aagcattaaa aaattcagcc agggaattag
   113461 gctgtgacat aaaagttgaa acgaatggag ctataggtgt agaaaataag ttaacagcaa
   113521 aagatatcga aatggcagat gcaataatag ttgcttgtga taaaaatgtt gatatggaca
   113581 gattcaatgg aaagccagta atagaagtac ctgtcaaaga aggtatacat aaggctaatg
   113641 aacttataca aagatgtatt gatggaaaag tagctattag aaaaggaaac ttatcaagca
   113701 gtaaaattgc agaagaagga aatttatcgt ttggtcaaaa gttgtataaa gacttaatga
   113761 atggtgtatc tcacatgtta cctttagtag tagcaggtgg agtacttact gctatatcat
   113821 ttttatgggg gatttattca tttgacccaa attcagaaca atataatcaa atagcagcta
   113881 cattaaaatc tgttggtgga tattctatga acttgatggt tcctgtattg gcagcattta
   113941 tagctcaatc tatatcggga agagctggta tgttggcagg acttgttgga ggaatgatat
   114001 catttgatac aggttcgggt tttttaggtg gaatcatatc aggattttta gcaggttact
   114061 tagttaaact atttgtacat ttgttaagaa aattaccacg acaattagaa ggtcttaaat
   114121 cgatttttat aattcctatt gtcagcgtag gtcttgtggg tgtagcaatg ttgttacttg
   114181 gtgggccatg ttcagcactt aacaatgcta tgatgaactt tctatcgggg ttacaaaatt
   114241 caagccctat aattttggga atagtaatag gatgtatgtc agcatttgat atgggaggtc
   114301 cagtaaataa agcagcatat gtaactggaa ctatgcttct aggacaggga aattatttat
   114361 ttatggcagg tgtatctgca gcttgtataa caccaccatt ggtaatagca atagcatcta
   114421 ctttatttaa aaatagattt acagaagaag atagagcagc aggattaatc aattatatac
   114481 taggtagtac tcatataaca gagggggcaa taccttttgc agcaaaaaat ccattaaaag
   114541 tgttgccagt acttatgatt gcatcatcaa tatcatcaat tttaacttat ataatgaaaa
   114601 tagaagtacc agctccacat ggagggtttt tggttctagg attagtcaat aagccacttt
   114661 tatgggtagg gtgtatattt gtaggttcat tagtaggtgc tgtactttat atgatggtta
   114721 cacctaaagt agtaaatgag aaaaatacta tagaaaatac aaatgcaaca aaagatgaac
   114781 ataaaaatga aagtgcagaa tcggaaaacg tatctaataa tatctcttta tatagcgaag
   114841 aaacagtaat tttagatgtt aagggaaaaa ataaaacaga tgtaattgat gaaatgattg
   114901 gaatacttga taaatctggt gttcttttag ataaaaagaa gtttaaagaa gaaatcctta
   114961 aaagagaaga aatatcatct acaggttttg gtatggggat agcgatacca catgcaaaaa
   115021 cagatgcagt aaaggtacca cgtgtagcag taggtgtatc aaaagaaggg tttgactttg
   115081 aatcagaaga tggaagcttg gcacatatta tatttatgat agcagctaca gataatggtg
   115141 ataatttaca cttaaaaaca ttatctcaac tatcttcaaa attaatgaat gaagaatttt
   115201 taaatgagtt attaaatagc aaaacaagta gagaaatagt atcaaaatta aataacgaag
   115261 aaatcaaatc agtataaaca tataggagga gaaattatgg cattagtgac aactaaacaa
   115321 atattattag atgcacaaga agggcattat gcagtaggtg catttaatgt tgaaaatatg
   115381 gagatggtta tggcagtaat agaggctgct gaagaactta aatcaccagt aatattgcaa
   115441 acaacacctt caacaataaa gtatgcagga ctagattatt atttagcgaa tgtaaaggta
   115501 gcatcagaga aggcaagtgt tccagtggca atgcacttag accatggttc aagctttgga
   115561 ctagctatgc aggcacttag agttggatat acttctatta tgattgatgg ttctcatgaa
   115621 agttatgaag ataatatttc aatatctaaa tctgttgtag atgcatgtat gccttcagat
   115681 atacctgttg aagctgaatt aggtaaagtt ggaggtaagg aagacgattt agatggtggt
   115741 gatgggggag catatacaga cccattagaa gcaaaagagt ttgtagagag aacaggggta
   115801 tcatctttag cagtagcaat aggtacggca catggattat ataagggaga gccaaagctt
   115861 gatttagata gattatctga aattagagat gttgtatcag ttccattagt attacatggt
   115921 gggtctggaa taccagatga agttattaag gaatctataa aaagagggat ttgcaaggtt
   115981 aattatgcaa cagaattaag gattgcttat agcaatgggg ttaaggatgt gcttaattct
   116041 gacccagagg taattgaccc taagaaatat ggtaaaaaag gtttagagtc agttaaagat
   116101 tttgttaaga gtaggatgga agtttgtgga tgtgtaggaa aagcaataga gatagtgaag
   116161 tgttaataat aaagggaaag aataagtaag attaaattaa ggggtgtctc aaaatgaact
   116221 ttttagttca ggaggcactc ttttttgtat taaattaaat atattttcat cattccgaaa
   116281 ataaaaaaga agattatatc tattttgaga cagcatctta ttttattttt tgattaagat
   116341 tataattgag aaatttgaaa taaggaagat gatataatta aataaaaaat ttctttctaa
   116401 gtttaaatta atattaaaaa gttataatat ggtaagagtt atccaggtag atgacttcta
   116461 tgctggatat atgataaaat aattttgtat gggatgtata ataatcataa aataagagta
   116521 ttgcattagt tttttaacta aaacatgtaa ataggaaaaa taatttaata actgtgtagt
   116581 aaaattttga atttaatata agacactaat tattaaggcg tacgactaaa atatatattt
   116641 aaattatttt atgaacactg gagggaaagt catatatgat tacaggagaa ttaaggagca
   116701 aagtagacaa gatttgggag acattttgga ctggtggatt aactaatcca ttagaagtta
   116761 tagaacaatt tacatatctt ttatttatta aaggattgga tgaagtagaa acaaaaaatg
   116821 aagcagaagc aactcttttg ggagtttctt ttgaaaggat atttgatgat ggacatcaac
   116881 atttaagatg gagtaagttt tctaatgaag gaaattcaga aaaaatgtat gaaatagtac
   116941 aaaatgaagt gtttcctttc ataaaaaaat tacatggaaa taaagactca gcttatgcaa
   117001 agtacatggg agatgcaata tttaaaattc ctacgcctct tatgttatct aaaatagttg
   117061 atggtattag taatttagaa ttaagtaagg atagagatac aaagggagat ttgtatgagt
   117121 atttattatc caaagtggct acagcaggta ctaatggtca atttaggact ccaagacaca
   117181 taatagatat gatagtaaga cttattaaac caacaccaga agatattata gtagacccgg
   117241 cagcaggttc ggcaggtttt ttagtatcat cacaacaata cttaagggat aatcattcaa
   117301 gtcttttctt agtgcaaggg ctgaaggagc attttaataa tggtatgttc tatggatttg
   117361 atatggatag aactatgctt agaataggtg ctatgaatat gatgttgcat ggcgttgaca
   117421 atcctaatat agagtataag gattctttat cggaggttaa tacagataaa gataagttta
   117481 cattggtgtt agcaaatcct ccttttaagg gaagtttaga ttatgaagca gtgtcagcag
   117541 atttattaaa agtgactaag acaaagaaaa cagagttatt attcttggca ctttttttaa
   117601 gagttttaaa aattggtgga agatgcgcat gtatagtgcc agatggagta ttgtttggtt
   117661 caacaggtgg acataaatcg ataagaaaag aaatagttga taatcataaa ttggaagcta
   117721 taatatcaat gccaagtggt gtatttaagc catatgcagg agtatctaca gctataatga
   117781 tatttactaa aacaggaaca ggtggaactg ataaggtatg gttctatgat atgaaagctg
   117841 atggttattc tttggatgat aagagaaatg agataaagga tagtgatata gaggatatta
   117901 ttaagagatt tgataatctt gatggggaag tagatagaaa aagaacagaa caaagctttt
   117961 ttgttgatgt ggaagagata agagagaatg ggtatgattt atctattaat aagtataaag
   118021 aggtagtgta tgaagaagta atttatgatg ctcctaatgt tattttaggt agggttaagg
   118081 agttagagaa ggaaatagct gttgggttag aagaattaga aagaatgtta gaggtatagg
   118141 gtatggagta tataaaatta aatgaattgt gctatataaa tattggcaaa acaccatcta
   118201 gaaatacttc tgattattgg ggaagtggta atagatggtt atcaatttct gatttgaaag
   118261 aaaaatatat attaaaatca aaagaagaga taacagattt agctgttgaa aaagctaata
   118321 tgaaattagt acctaaaaat accgttgtaa tgagttttaa gttgtctata ggtagagttg
   118381 ccatattaaa agaagacatg tttacaaatg aagcaattgc taactttcaa ataaaaaata
   118441 atgaacttat aacatatgaa tatttatatt atgctttgag aactttaaat tttaataata
   118501 ctgatagagc agttatgggt gcaactttaa ataaaagcaa gttaaatgat ataaaaatac
   118561 catatttcac aatttgtata caaaataaaa tggtagaagt tttaaataaa gctcaagagt
   118621 taataaataa aagaaaagag caaatagaag cattggatga attagttaaa tcaagattta
   118681 ttgagatgtt tggaaatgtg attactaata gtaaagattg ggatacagag ttattaggag
   118741 agatatcaaa cttaaaagct ggaaaaaata taaaagcaaa agatatttat gaaaaaaatt
   118801 cacatgaatt atatccttgt tatggaggaa atggtttaag gggatatgta aaaatgtatt
   118861 cacataaggg aacatttaat ctcataggta ggcaaggagc attatgtggt aatgtaaaat
   118921 atgtaaatgg aaagttttat gctacagaac atgcagttgt agtacaacct aaagttgata
   118981 taaatagtta ctggctatat tttacactta aagagttaga tttaaatcga ttatcaactg
   119041 gagcagcaca accaggtctt acagtaggca aattaaatga agttgaaata cctaaagtac
   119101 ctgtatatct tcaaaataag tttgtggact ttgtcagaca aatagacaaa ttgaaatcaa
   119161 gaatggaaga tagcttaaaa gaactagaaa acaactttaa ctcattaatg caaaaagctt
   119221 ttaaaggaga gttattcaac taaaatacaa ttattaaaat gggggaataa aatctatgaa
   119281 tcaaatagag ctagatttat accataacat ggtaaatatc tataaagaag ctaatttaca
   119341 atgtaactat aagccaacaa gatttttaca actgataaat aacaaaggag ccttattagc
   119401 tgctaaagaa ttaatcaata aagaaggagc tactgaagga tttacaaggc tatgggagtg
   119461 taagagatta gatttatcat tagaagtatt agtattaaaa gaaaagtata aagagttgtt
   119521 tactgatgaa gaaagagaaa tatgtataaa tagattaaaa gattatggat ataaatttaa
   119581 ctaagcaata ttacctaata aacaagaggt gattaaatga gaaatatacc aaatgagatt
   119641 aaaaactcaa taataaatgt atttccaaaa gaaaatactc tagcaatcat aatatttggt
   119701 agttatggaa cagataaaca tacatcagaa agtgatatag acatagcttg gattcctatc
   119761 aaaaaagtac caattacaga acttgcaact aagacagaag ctctaagaaa tatattagac
   119821 attgatgtag acctaaaaat tgttacagat aattatacaa tagcacttaa aaaagctatt
   119881 ttagaaggtg aagttattta tgaatctaaa gattttaagg attatataaa taaattctat
   119941 tttgaaaaca gtgatgtaat agatatctta gattggaggg acatgtatgg taattagaaa
   120001 caaattatct tggaactcaa tagaagaagt aaatagggat tttggttctt gcttgtatga
   120061 cctgcaaaac ttcaaaatct tatatgataa ggaagaaatg cctgagttat gggctagata
   120121 cataaaagaa ggctttaaaa gctatatggt atcatttcta gaattaacaa aagcaatgtt
   120181 gtattataaa tcaattgatt taaacataaa atctaaaaac ttttatgact accttttagc
   120241 ttgtgagtat cacaatttat tacctaaaaa ttcttctata gttatagaaa cacttagaaa
   120301 attgagaaat gatgattctc atggatatga tataccacag tttgaagata tgtacgaatt
   120361 gtttacagaa aatgaagaag tatttgttag tataagaaac agctgtaaga aatagttttt
   120421 agagagattt attttaacta agggacaaaa gggggataaa agccttgggt aattttgatt
   120481 ttttacaaaa gaagaaaaat ttcaatagtt ttaatactgc ttgcttagaa gcagaaaaaa
   120541 gtatactagt tagcccatct acttgtgcaa ctataacaag aagagcttta gagcttgcag
   120601 taaaatggct atatgctaat gatagtgatt tagtattgcc ttatcaagat aatcttagta
   120661 cgttgattca taataatagc tttatagaac ttatagacta tgatatgtta cctttattaa
   120721 aatatatagt taaattaggt aatttatctg tacatactag tgcgaacata gagagaggag
   120781 aagcaatact ttcacttaac aatttgcatc aatttgttag ttggatagac tattgttatt
   120841 cagatgaata tacagcagaa gactttaatg aagatttatt acttcatggg gaagagaaaa
   120901 ggacgagacc agacgaactt aaaaatcttt atgagagatt aagttcaaaa gataaaaagc
   120961 ttgaagaagt aataaaagaa aatgaggaat taagaaagtc actaactgaa aagagaaaag
   121021 ttaatactgt aaactatgat ttcaagatag acgaagtaag cgaatttgag acaagaaaaa
   121081 gatatataaa tatagaatta aagcttgcag gttgggaatt tggaaaagat atatgggaag
   121141 aaatagaagt acaaggtatg cctaatgaaa gtggtgtagg atatgtagat tatgttcttt
   121201 atggtgaaaa tggtaagcca ttagcagtag ttgaggcgaa aagaacgagt aaagacccga
   121261 aaattggtca acaacaagct aaattatatg cagattgttt ggaaaagaga tatagtcaaa
   121321 gaccggtaat atttttgact aatggttttg atatgtatat ttgggatgac tattcagata
   121381 ggaaagttta tggattttat aaaaaatcag aattacaact tatgatagat agaagaaaga
   121441 gtaagaagtc tttaagttct gtaacaataa atgatgaaat atccaataga tattatcaaa
   121501 aagaagctat tagggctgta tgtgaggctc ttgaaaataa gcaacgcaaa actcttttgg
   121561 tatgtgctac tggtacagga aaaacaagaa ttgctatatc tatagttgat gtactttcaa
   121621 gacataattg gattaaaaat atattatttc tagcagatag aaaagcattg gtaaagcaag
   121681 ctaaaaaaag ttttactaag ctattaccta acttggcgtt atgtaattta ttggatagca
   121741 aagacagccc agaagatgct aggatgatat tttctacata tccaacaatg atgaatgcaa
   121801 ttgatgatac gaagtctaag gatggaaaga gattgtttac acctggtcat tttgatttaa
   121861 ttataataga tgaatcgcat agaagtattt ataaaaagta taagtcaatc tttgattatt
   121921 ttgattctta cttaatgggt cttactgcta caccaaagga tgagatagat aaaaatactt
   121981 attcagtttt tgacatggaa aatggagtac ctacatatgc ttatgagtat aataaggcag
   122041 tcgaggatgg atatttagta gattatacta gtattgagtt taagactaag attatggaag
   122101 atggaattaa gtatgatgag ctttctgatg aagagaagga agaatatgaa aatacattta
   122161 atgatgatga gagtattgga gacgaaatag ggaataatgc agtaaatgag tggctattta
   122221 attctgacac aatagattta gttttaaata agctaatgac agaggggttg aaaatagaag
   122281 gagaagaaaa gattggtaag actataattt ttgcaaagaa tacaaagcat gctagggcaa
   122341 tagttgaaag atttaataaa ctgtatccaa agtatggtgg gaactttgta aaagcagttg
   122401 actatagtat aaattatgta gattctataa tagatgattt ttctgataag aataaattac
   122461 ctcaaatagc agtttcagta gacatgcttg atacaggaat tgacatacct gaaatactaa
   122521 atcttgtttt tttcaagaaa gtgagaagta agactaagtt ttggcaaatg ataggtagag
   122581 gaactagatt atgtccagat ttattaggtg ttgatatgga taaggaaaga ttcttaatat
   122641 ttgatttttg taataatttt gaatttttta aatttaatcc taaaggattt gagggaaata
   122701 aagcagaaac acttactgaa aaattattta atataaaggt aagtatggtt aaagaacttc
   122761 aagatattaa atatatagaa ggtgagtatg cagaacttag aaaagaattg ttagaagaac
   122821 ttataacttc tgtaaaagct ttaaatgagg atagttatat agttaggatg aatttaagtt
   122881 atgtacataa gtataaaaat gaaaatgttt ggagcaatat tggagcagta gcacaaaatg
   122941 agataagaga atatatatca ccactcataa cttcatatgg tgatgatgaa ttggctaaaa
   123001 gatttgatgt agttatgtat aatatacaac ttgcatactt acaaaataat aatgcaagta
   123061 aaggtataag gcatgtaatg gctacagcag aaaaactttc aaaacttggg actataccac
   123121 agattcagca acaaaaatat actattgaaa aagcaatgac agaggatttt tgggaagatt
   123181 cagatatatt tgaggtagaa gaagtacgta tatcattaag agagcttatt aagtatcttg
   123241 aaaagtctag tcaaaagata tattatacaa gttttgaaga tatgattgta gcagaagata
   123301 gaaatgattc tgtatataat gcaaacaatc ttaagaatta taaaaagaag gtagagtatt
   123361 atttaaatat ccataaagat gaattagcaa tatttaaatt aagaaataat aaaaagataa
   123421 caaagcaaga tgttgaaacg ttggaggaaa tactcttaaa acagttaggt aattgtgatg
   123481 attataagaa ggagtttgga gatactccag taagtcaatt agtgagaaga ctagtgggat
   123541 tggatagaga agctgcaaat gaagcttttt cagagttttt aaataataag agctttaata
   123601 ctaagcaaat acattttgtt aaacttatag tcgattatgt agtcaagaat ggatttatag
   123661 aggataacaa agtgttgatg gaagacccat ttagaactgt tggaagtata attgatttat
   123721 ttgaaaatca tattgaagag agaaataaat tgattaaaac tataaataaa attaaagaaa
   123781 atgcatcaga gataggctaa tgatgttatt tagtgcaaaa ttattgttaa tgatgtagag
   123841 aataaattta ttagtaggta gtctaatatt gggttgaaat agataactag atatggataa
   123901 tgtaaatata caaagagagg tattgaataa ttatgcaata tctcttttta attgataaat
   123961 aactatgaat tactcatgaa gaagattaaa taataatttt taaaattaag tatttgtata
   124021 ttttatagaa taatcatgta tttactttaa taaaataaaa acaggtataa aaaggtatat
   124081 aataaggctt tcatatacat ttatgagtca aaattttgat ataatatata gatacatgga
   124141 gttatgaatg gaatttattt aacttatagg gggagttaat atgaaagcag gagaaattga
   124201 atttcttagt tatttagagg ggtcaaacaa aagttttgta gtacctgtat atcaaagaaa
   124261 ttataactgg aagaaagaac aatgtaaaag attgtttgat gatttagagg atataataga
   124321 ttctggattt agaactcatt tcttagggtc agttgtatct atatatagta tgggaaaaga
   124381 atatttaata atagatggac aacaaagagt gactactgtg tcaatattat tgattgccat
   124441 gtgtcaaata ataaaagagt ttggggaatc aaaaggaatt attacaacag aagaacagat
   124501 taaggagtgt tatcttataa acaagcactc aagagataaa gatggaaaaa taaagttaaa
   124561 accaatagca gaagatagaa aagcgtacta tgaactattt gaagaagaaa tgaatacaga
   124621 tagaaattct aatatagttt caaattattt atatttttat aatagaataa aagaagataa
   124681 tatatcaata gatgatttgt ttgatgctat acagaaatta actatagtag aaatagagtt
   124741 aaaaaatggt gaagatgacc ctcaattaat ctttgaaagt ctaaattcaa ctggcttaga
   124801 tttaagtgaa gctgatagag taagaaactt tgttttaatg ggtagaagct ctaagttaca
   124861 agaggaattt tataataatt attggtataa aattgaaaaa gatacaagta gcaacgtaag
   124921 tagttttata agagactatt tgactataaa ggagagaagt ataccgaata aaaataaagt
   124981 atattttagt tttaaaaggt atgtatcaga taatggtata gatatagaaa ttttattaaa
   125041 agatttactt aaattttcta actattatag agagatatct tattcatgta ctgatgataa
   125101 tgatgtaaac aaagttttga aaaggataaa caaacttgaa atatttgtat catatccgtt
   125161 tatattagaa ttatttgatg attataatga aggtataata aataaaaaag tacttgtaga
   125221 atcccttaat ttagtagaat gttttatatt aagaagaata gtatgtgatg tacctccgaa
   125281 tgcactgaat aaagtattta tgaacttagg aagggaaatt aaaaaattta gtgattataa
   125341 agaaaactat tctaatatat taagatatat ttttataaat aagaaatcat ctcaaagatt
   125401 tcctactgac agtgaatttt caaatgcttt tgaaactaaa gatatatata atactaagtc
   125461 aaagaataag ttatatatac ttgagaggtt agagaattat aataataaag aaattgttga
   125521 tttagaaaat ttaatcaata ataatatgct aaatatagag catataatgc cacagacatt
   125581 aacaaataaa tggaaggaat cactaggaga taactataag gagatacatg ataaatattt
   125641 acatacaatt ggaaatttaa ctttgacagg atataattca aaactaagta ataaaacatt
   125701 tgaagaaaag aaagaaatgg aagatggatt taaagatagt aggctttatc taaataaata
   125761 tatttcatct atagataaat ggaatgaaga agaaataaaa aatagaacta agatattact
   125821 agatagagct gtagaaattt ggaaatatcc aagtgttaca tatgaacctc caagtaacag
   125881 tgaaaatata tttacgttag aggatgatga tgttaatttt acaaatgaaa gtatagtatc
   125941 atttagtata ttaggagagt catataaggc taaaaattgg acagaatttt atgaacaagt
   126001 tgctcttact ttatatgatt tggattctgt aaggtttaac agtattgtag acaagactta
   126061 taaaagagat tttatagata atattaagtc tagagatgca tataaattaa gaaaaggtat
   126121 taaaatatca gaaaatatat atttagaaac aaatttaaat acagaggcta aattaaatat
   126181 aattagattt ttacttaatg agtttgatat agagttaaat gaagtaatat tttccataaa
   126241 ataatgaaat atatgcattt tttgcgtaat agaatattaa ttatattaaa aataaaatag
   126301 cacctcttga tatagattta tagctcaaat ttatatcaag aggttacgtt taattaaagt
   126361 aatacaaata ctatctaatt aaattattaa taaaaatgtt atataaaaat gagtatatag
   126421 cattttaaag agtaataaac cttacataat aaatgattta ttaatatgaa ctagaagtat
   126481 ttttactata ttgttttata aaacctttag gcattttact tataaaatat accaccataa
   126541 tacaagacaa aggtttgtct actatattac taagaatcct tggaaagaac gcagcagtaa
   126601 atatcttctg accagactga actaaaaaac caaccaataa atcagcacca cttccactta
   126661 aaccaccaaa caataaaact gaaataggag taccaattaa aggacaaaca atagataaaa
   126721 ttactcctgt aataatagct tctttataac caaaaccttt tttcttagaa atatatccaa
   126781 caataagacc aagaacaata tttacaaggg caaaaggtat atttgtagga cctgatataa
   126841 cacctaaaac taagtttgta cacccaccaa taagagcacc ccaaaaagga cctaatacga
   126901 cagccccaag tacagtacca attgtatcta aaaataataa tggtatattt atcatagata
   126961 taaccatacc taagacaata ttaataacta tgcacattga agaaaatgtg acttttttag
   127021 tatccaatta taatacctcc taaaaaaata tatacattta tcatagtata gattataaaa
   127081 gattactaat tgtatatttc tatatagaat attggaaata tagaacaaat aaataatata
   127141 attatcaaaa tatgtagtat cattaaaatt aagaataact aaggagatta ttatgaagag
   127201 aaatagagag attgtagtag tatgtcattg tatattaaat tgtaattcta aagtagaggg
   127261 attgtcagaa tttaagggag cacaaaatat agcaatagat ttaataaata aagggtatgg
   127321 aataattcaa ctaccatgcc cagaaatgat tatgtatgga ataaataggt ggggacatgt
   127381 aaaagaacag tttgacaatt tgttttttag agaacaatgt aggcaaatgt taatacctca
   127441 tgtaaggcag tttgatgaat atttaaaaaa tgattatgat ataaaaagta tcattgcaat
   127501 agatggcagt ccaagttgtg gttataataa gacatgtagt tctaaacgtt ggtttggtga
   127561 gttaagtggt tgcaatgaat tgatggataa aataaatgat atacaaatgg tggatgggaa
   127621 aggtattttt atagaagagc tagaaaagct acttaaagaa tataatttaa atatacctat
   127681 agttggattt gacgagctta gagaagataa gtagagatat aaatatttat tgtctcatta
   127741 tgaaacacca ttatatttgg cagaaaaata tgactgatgg acagtacagg aaccattttt
   127801 aagtggagta attagtactt ataaagatgt atccactagc tgaaagaaaa tgtagaaagg
   127861 taataaatga attaagaagt agataatata tataaagggg tgtctaaaag tgaacttttt
   127921 agtttatgag acactctttt ttttatatta aatcaagtat attaaatcaa atatatttta
   127981 atcattttag caatgaaaaa taaatttatc tatattttga gacaacatct tttttagttt
   128041 tatttatttg ttgtcgtttt tgacttggta tacaattgta tattttctta aataatttaa
   128101 taaattattt ataattataa aatccattgt ttttaacaat atctaatata ttattatttg
   128161 tatttataag gtcactatac agattttcaa gtacgatatt atctatataa taggcaaact
   128221 ttattcctgt atgtgtttta aaaaaactag atgtatatag gtatcatcac agatattaaa
   128281 agtataaata aaagatatta agaacgactt tccagcaata tattagaaaa ttttactaaa
   128341 atccggaaag cgattgacaa acaaagtcaa ataaagtata ttattggtaa gttagtttaa
   128401 tgtacaaatg aattatatat aaaacctaat ttataaataa cgatactaaa cgacattatt
   128461 taacttaagc tacacaaaga tagaatatta taccattgat ttaggaggta gccgtgataa
   128521 aaatatctga agactatatt gaaaaaagat ttgacaatga actattgcga atagaagcat
   128581 ggggaaaaaa ctctttacgt attaggtcgt ttgtagacca aaattttgtt gatgaaaact
   128641 atgctcttaa cgaaaaacct aagttaaata aagatgatat tacaattaat aaaaatgaag
   128701 atggaagtgc aatcattaaa aatggaaaga taaaagctgt cttagaccat agagatagaa
   128761 ttacttttta taatgataaa aatgaaatat tattgaaaga atatattcga ttaagagctg
   128821 taaaacatga tgatggtgga gaagatgtag ggacaattga gattaccaaa gactttaact
   128881 ctactctaaa gttaaaatca agagaatatc gaccaagcta tagtggagaa tttgaagtaa
   128941 ctactagatt tgaatctgag ccttctgaaa agatttttgg aatgggacaa tatcaacata
   129001 aatttttaga tttaaagaat actgttttgg agttagccca aagaaattct caaatatcag
   129061 ttccttttta tatttctagt ctaggttatg gacttttatg gaataatccg ggaattggaa
   129121 aagtatcttt tgctaaaaat atgacagaat ggaagatgtt ttctacaaat tttatagatt
   129181 attggattac ttgtggagaa agcccaaaag agttaaataa aaattattct caagttactg
   129241 gaactgttcc tatgatgcct gaaaaccttt taggactatg gcaaagtaaa ctaagatata
   129301 gaacttcaga agaagtttta gatgttgtga aggaatattc taaaagagga attaagcttt
   129361 catcaattgc aattgactat tttcattggc ctaagcaagg tgaatataaa tttgacttag
   129421 attattggaa aaatcctaaa gaattagtta aaaaattgaa agaagagtat tcagtagaac
   129481 caatagtatc tgtatggcct acagttcaaa gtgatgcaga aaactacaat gattatttag
   129541 aaaatggcta tttagtcaat gttaatcgtg gtgttagaat gacaatgcaa attcaaggaa
   129601 atacagtctt tgtagatatg acaaatgaaa atgcaagaga atatgtttgg gatagaatag
   129661 ataaaaatta taaacaactt gggattgact attattggtt agatgtagct gaacctggct
   129721 attctgtgta tgattttgat aactatagat ataaaaaagg aaatgtttta agttgtggta
   129781 atatttatcc tattgattat ttaaaaatga tttatgatgg tttacataat gacatagagt
   129841 ctgttgtaac tcttgtaaga ggagcttggg caggagctca aaagtatgga gctttagtat
   129901 ggtctggtga cattgattct agttttgaag cttttaataa tcaagtaaat acagggttaa
   129961 atatgggact ggcaggtata ccatggtgga ctactgatat tggaggtttc catggaggaa
   130021 atcctaaaga cccagaattt agagaactta tggtaagatg gttccagtat gctacttttt
   130081 caccaatttt gagaatgcat ggagatagat tgcctcatag taaaccatta tcaaataaag
   130141 gtggaggctc aatggtaact ggagctccta atgaaatatg gtcttatggt gaagaagttg
   130201 aagtaattct tacaaaattc ataaaaatta gagagagctt aaaaacttat ttaaaaaaac
   130261 tgatgaaaga agcgcatgaa gatggaacac cagttatgag aactttattt tatgaatttc
   130321 ctgaagatga taaaacttgg gaggtggata atacatatat gcttggagat gaaattttgg
   130381 tagctccaat aatgaattat aaagatagaa gtagaaaagt atatttacca aaaggacata
   130441 catgggaaaa tatatttagt ggagttagtt atgaaggtgg gaaaacttat gaagttgaat
   130501 gcccactgga agaaattcct attttcctaa agcaagattc cagttataat tttaaagaac
   130561 taaaaaatat tttgggagag gtgaaatcat aatggagcca caattatggc aattattatt
   130621 aatcgtacta tatggatttt ttataaacta tgaaaaaaat tcaacaatgt ttggaacata
   130681 tcaaccagta acagcaggtt ttattactgg tcttatctta ggagatataa atacagggtt
   130741 atatattgga ggtacattac agctattatc attaggtatt agtaactttg gtggagcatc
   130801 aatacctgat tatcaaacag caagtatagt agccacattt ataactatta cgactaagca
   130861 agaagcatct gtaggaatct ctataggtat tccagttgct ttattgatgg tacaattaga
   130921 tgttcttaga aatactattg gtatatggct agttcataaa gcagaagatg gagctaaaaa
   130981 aggaaattat aaaaatataa cctatatgca aatgttagga gtactattaa cagcagctac
   131041 aacaggtatt ccagttgctc tatctgtaat atttggacct tctttaatta ataccatttt
   131101 gaaatataca cctgaatggt taacaggtgg tttaacagta gctggaggac tacttccagc
   131161 agtagggata ggattattac ttagatatct tcctgctaag gagtatttta gttacttagt
   131221 aattggtttt gttttagcag tatatatgaa agtaccatta ttaggtgtag ctttaattgg
   131281 tggagcaatt gcacttataa tttacaaaaa gaatttggaa aatcaagaac aacaatatac
   131341 tgtagtagga ggtatggacg aagatgagtg ataaggtatc attaaataaa tcaaatgaaa
   131401 aggtgaaaaa aagtgtctta tggcgctggt tttttactag ttctgtttct tcaaattatg
   131461 agaagatgca ggccttggca tactgttatg cagtactacc ttttttaaaa gtagtataca
   131521 aagataatcc agaaaagtta caaagtgctg tattaaatca tttacaattt tttaacacta
   131581 atccttgggt tgccccttat attttgggta ttaatgtagc aatggaggag ttatcaagtg
   131641 aagagactga agaggctgtt gcttcaatta aaacaggctt gatgggacca gtagcaggtt
   131701 taggagatag tttatttgtc gttattccgt ggacaatttt tggagctata gcagctaata
   131761 tggcgataga tggaagtcca tttggaatct tactgtggat tgtagtgagt gtagcattga
   131821 aattattaag tataccacta tttaatgctg gttatacatc aggtactaag ctaatatctt
   131881 caattgaaaa aagtttaaag attttaactg agagtacatc tattttaggt ttaatggttg
   131941 taggtgcatt aataccttca gttgtaaaag ctaatgttgc tttgaacttt caacaaggtg
   132001 attttacaat gaaaggtcaa gaaatattag accaaattat gcctgggtta gttcctgcaa
   132061 ttctagttgt gattgtttat tgggctctta aaaagaatat aaaacctata tacttaattt
   132121 taggagtaat ggttgtttca ataattttat atgcattagg tattttaaaa taaggaaagg
   132181 atgatattag atatggaaat gaaaggtatt aaaaatattc gtatagatga ccgtttaatc
   132241 catggtcaag ttgcaactat gtggagtaat aaattgggtg ttacaagatt aatggtagta
   132301 aatgatgcag tagctaacaa ttctgttcaa aaacaagttt taagaatggc tacacctgca
   132361 ggtatagcgt catctataat tacagaagag actgctataa aaaatattac tgcaggaaag
   132421 tatgaaggac aaaatgtatt attaattgtt aagtctcctg tggaccttat tccatttgta
   132481 gaggcaggat ttaaaataca taatataaat gtaggaaata tgtcaagtag aaaagataca
   132541 acagttctaa gacctaatat cagtgttact gaagaagaga aagaagcatt taaaagactt
   132601 ttagatgaag gaattgaaat tacaactata atgacgcctg atgataagaa aacttatctt
   132661 gtagacatct tatagattta aagaggtgta ttaaagtgaa tagtattatt ttgatgagtc
   132721 atggcaatat ggctgaagaa gtcttaaatt ctgcaaaaat gataataggg gattctatag
   132781 attatcctac tgtaaatatg aaacaagatg atggaataga aggaacaata gaaaaattaa
   132841 aaaaagcttt agaagtgtac aaggaaagtt cagaaataat tataatggca gatttactag
   132901 gtggaactcc atgcaatgct gctttattag tagccaataa tgacagtcga attaaaatta
   132961 tttcagggct aaatttaggt atggttattg aatcagcttt tttagataca aaggaattgg
   133021 cagcaaaatt agagaaaata ggtaaagata atatttctat ggttgaacaa aatgcaagtt
   133081 tattatctga tgatgagtag gaagattata ttaatattta aaacgaaata cttatgttaa
   133141 tacttaattg atatacaatt tttaaaaaat atagctaatc ttgcataaac tatataataa
   133201 atctaatttt agaatgtata atttaaaggg ttatggctgt atatagtcat aacccttata
   133261 tttcattaat taaagttaaa ttttgtatat tcaaaaagct cttgatattt acggcagagc
   133321 caccatatag agatgcctca gaccctaatg atgaaatttc tatatttatt cctttgttaa
   133381 aagagctaac taacatatct tttgtaatct gtaatatctc agggatatca ctaattattt
   133441 ggctatttaa atatattatt tcaggagcat aagttgtaat agcattattt atagctattg
   133501 ttaagtaact acaaaactca tgaataactt ttttggcatt ctggttatct tcataatata
   133561 gttgctttac tatatcagaa tctattttag gaatattttc taaagaagaa agctgttcaa
   133621 ataccttttt ttctgaacaa tactgttcta aacagccacg atttccacaa ggacatagtt
   133681 taccgttagg catgatgata gtgtgaccaa tttctccact cataccattt ctgccactat
   133741 ataatttatt atttattata atgcctgaac caaatccact gtgaatactg agactaagta
   133801 gtgagttatg tacagttgaa aaagtattct cagctaaagc tgttaagttt gcttcatttt
   133861 ctatatgaat aggaaagtca tactttttgc taaggatgct atataagtca atctcattaa
   133921 gattgtaata tggagtaaac aatactttat tttcacaagt aatcccatgt atagccaaag
   133981 taagaccaat taccttataa ggagtgtcta ttttggatat gttataacta tttataattt
   134041 catctatcaa ttgtataaca ttgtctttac ttacttgtat atctgttaat ttcttagaat
   134101 ttataatagt tccatctaag taagatagag aagaaaatat atagtcgtat ccaatgtcca
   134161 tacttaaaga aatccctgca catttattaa atactaataa tatgggtttt cttccgccac
   134221 tatgagtact atttccaatt ccgatttcat gaactagaga ttcatcaata agttttttgg
   134281 taatagcgga tatagttgct ttattcaatc ctatagtaga agctatactt gccctagaaa
   134341 taggaccatt ttttataatt tgttcaagta ccaatctttc attcatttct cgaatagtgt
   134401 atttatcagt aaccaatttg atattcctcc ttaaaataat attgtaatac tttttacaca
   134461 aaaataaaag gttattttgc attgacaaag ataattaaat attttattat tagttcataa
   134521 gttagtttaa tatactaaca aaaataaagc aagtaaaata tacctaaaat ataaaaaaat
   134581 taggatagga aaacgatagt tatgaagtgg cattcaagga gggatgaagt tggagtatgt
   134641 attaggtgtg gatattggta catcaggtac taaaacagtt ttatttgata aactaggaaa
   134701 tactataaaa agttgtacat atgaatatcc tcttatacaa gagaaatcag gttgggcaga
   134761 gcaggatgca aatgattggt ggaaagctgt agtcgaatct ataagagaag tagttcaaag
   134821 tttaaatata agcagtgaat gtataaaagg aattggatta tcagggcaga tgcatggtct
   134881 agttatgctg gacaatgaag gtaaaacatt gagaaactct ataatatggt gtgaccaacg
   134941 aacagtaaaa gagtgtgagg agataactga tttagtaggt gaagaaagac tgattgaaat
   135001 aactgctaat ccagcactta caggatttac agcatcaaag atattatggg ttagaaacaa
   135061 tgaaccagat atatataaaa atactaataa aatacttctt ccaaaagatt atataagata
   135121 caaattgaca ggtgaatatg ctacagaggt atcagatgca agtggtatgc agttgctcga
   135181 tataagaaaa agagattgga gcgatgaagt actagaaaag ttaaatatag ataaaaatct
   135241 tttaggtaaa gtttatgaat cacaagagat tacaggttat gtgactagag atgtagcaag
   135301 tttgacaggg cttaaagaag gaacaatagt ggtaggagga gctggagacc aagcagcagg
   135361 agctatagga aatggaatag ttaaagatgg agtagtttca tctactatag gtacatcagg
   135421 tgtagtattt gcttatacaa aagagccaaa aattgataaa gaaggtagag ttcatacttt
   135481 ctgtcatgca ataccaaata catggcatgt tatgggagtt actcaaggag ctggattgtc
   135541 attaaaatgg tttaaagata atttctgtca aagtgaagtg gaagtttcaa attctttagg
   135601 tgaagatgta tatgagatta taaataatca agtaagtcaa gtaccaacag gatgtaatgg
   135661 attgctttac ttaccatata tgatgggaga aagaactcct catcttgacc cttatgcaag
   135721 aggtgtgttc tttggattat ctccaatcca ttctaaaaaa gaaattgcaa ggtcaataat
   135781 ggaaggtgtt tcatatagtc ttaaagactg tatggatata atagagaatc ttaatataga
   135841 cgttaatgaa gtaagagcct caggtggagg tggaaaaagt aaagtatgga gacagatgca
   135901 agcagatatg tttaatcaag atgtatatac tataaattca agtgaaggac cagcacttgg
   135961 agttgcaatt cttgcattag taggagctgg aatatatgaa aatatacaaa aagcatgtga
   136021 tgctataata aaaacttcaa ctaaattaga accaataagt gaaaatgtag atacatacaa
   136081 tatatatcat agattgtata aaagaatata caaatctttg aaagatgact ttaagttatt
   136141 agatgaagta gttaatgcaa aaataaataa ttaaattagc ttaaaaagaa aaataaagat
   136201 agaaaatagt tttaaattaa gaaaacatac tacatatatt atatgtgtaa aatattagga
   136261 ggacatgaaa tgagtgaaat atttaaagga ataggacaga taaaatttga aggagtaaaa
   136321 tctgacaatg aattagcatt tagatactac aatcctgaac aagtggtagg taataagact
   136381 atgaaagaac acttaagatt tgcaatgagc tattggcata ctttatgtgg agagggtaat
   136441 gacccatttg gagtaggcac agtagagaga ccttggaata atataacaga cccaattgag
   136501 atagcaaaga ttaaagttga tgcaggattt gaatttatgt ctaagatggg aattgagtat
   136561 ttctgttttc atgacagaga tatagcacca gaaggaagag atttagaaga gacaaataag
   136621 atattagatg aaatagttga gtatataaaa gttaatatgg aaaagacagg tataaagtta
   136681 ttgtggggaa ctgccaatat gtttggaaat ccaagatttg ttcatggtgc atctacaaca
   136741 tgtaatgcag atgtatatgc atatgcagca gctcaggtta aaaaagctat ggaaataact
   136801 aagtacttag gaggagaaaa ttttgtattc tggggtggaa gagaaggtta tgaaacttta
   136861 cttaacacta atacagaact tgaaatggat aactttgcaa gattcttaca aatggctgta
   136921 gattatgcta aggaaatagg attcactgga caattcttaa tagagcctaa gccaaaagag
   136981 cctactaaac atcaatacga ttttgatact gctactgttt taggattttt aagaaagtat
   137041 aatctggata aatacttcaa aatgaatata gaagcaaacc atgcaacact tgcaggacat
   137101 actttccaac atgaattaaa tatagcaaga ataaacaatg ttttaggtag tatagatgca
   137161 aatcaaggag acctattatt aggttgggat acagaccaat ttccaacaaa tatatatgat
   137221 gcaacacttg ctatgtatga agtgttaaag caaggtggaa tagcaccagg aggatttaac
   137281 tttgactcta aagtaagaag agcatctttt gaggtagaag acttattcct agcttatatt
   137341 gcaggaatgg atacatttgc aaagggatta ttaatagctc ataaattatt agaagatgag
   137401 gtatttgaaa actttactaa agaaagatat gcaagtttta gtgaaggtat aggtaaggat
   137461 atagtagaag gtaaggttgg atttaaagag ttagaatctt atgcactgca aatgccagtt
   137521 ataaagaata agtctggaag acaagaaatg ctagaagcta tacttaacag atatatatat
   137581 gaagtagata caatttctaa taagtaattg tgtagtaatt aaacttggat gtttaaataa
   137641 aataacagga tatgttcttg tttttattct aaaacggaca aagataagta tttgtaaaaa
   137701 ttctcataat catgataaat taaggatata gacttaagta taattagttt atatccttaa
   137761 aatttctata aaaaataatc atttctatag ttatcaatat ttttaattat caatatcttt
   137821 ctcaactaat aaataaaaat cagtaaagta tataaattta agtcattata atggataaat
   137881 tttttagcat atctttttta gtatatcact gataagaatt tactttcagg atatagcagt
   137941 aaaatagata tttgaatata attgttattt tataactttc atgaaataat tttgaaaata
   138001 caaataaaaa tttttaaata gaataatagt ggaatatatc ttcaagaatt tcttttaact
   138061 gtttaggtga taataaaata atgatacaat gtattaaaat ataaaatctg aaagtggatg
   138121 agaattacat gaaaaagaaa gtattatttt tagtaattat tttagcattt ataatattat
   138181 taggtaattc tacttattct caaaagaatc agttgtctga agaggaaaag gtggatgact
   138241 ttaattatgt gtataatgtt gtaaagacag gatatccata tctaggtgta aataagaggc
   138301 ttaataatat tgattggtta gcaaataagg atgaatatac aaaacgaata aaaaacactg
   138361 aaaatgatga agaatttata gaagaactgt catctatatt atctgattta aataataaac
   138421 acacagaagt aatagataat aagaaaagat atgaactttt taagaaatca tactctaata
   138481 atgattggta tgattttctt aatgataaaa aagttgtgga tagatatgac tctatgaatc
   138541 ttaaaataaa aatgccagat gatatttttg taaaaaaaga attaatttta aaggatgtta
   138601 ttaagggtca gattggatat atgtatttac catcaatgtc atcaaagaat ggctctataa
   138661 ataatgattt aaaaataatt ggagattata ttaacacttt agaaaaacat aaagctttaa
   138721 ttattgatat aagaggtaat ttaggtggaa gtgatagtta ttggcaagga atcgtatcta
   138781 aactcataaa aaatgatgtc aaaataaatg gttatagaat ttatagaaat aataatgaaa
   138841 tagtaaaaaa atatacaaat gcaagaaata taaaattaaa tcctgtagaa aatttaccag
   138901 caagtgtaaa ggaaaatgca cctaaagaaa ttataaaaga ttttaatgat tttgaagata
   138961 cttcctatac tataaaatct acagatgatt caaaatttaa gggtaatata tacttacttg
   139021 ttgatagaaa aatatattca tcatcagagt catttgcaat gttttgtaaa gaaaataaat
   139081 ttgcgacttt agttggtgaa actactggcg gagatggagg gtgtatagac cctgtattgt
   139141 ttaatttaaa aaatagtggt ctaatagtta gaatggcaag ttgtatgtat ttaaataaga
   139201 atggaatatg tgatgaggaa tttaaaacta ttccagaatt taaagtaaaa gattgtaaaa
   139261 ggactgctga ttttaaagat gataattgta taagaaaagc actagaactt gaaaatatta
   139321 attattagat aaaagaataa aattaaaact acattttttt aaacatcaat tatagcagta
   139381 ttttttatag tcaattttat gggctaaata gtaaatataa gaatacgctg taatttaatg
   139441 ttgaatattg gtataatatt tatgacgatt tttaattaaa gggggtaata gtttatgaga
   139501 ttagaagaaa tgattttttt aaattataat aaattgaatg atacagattt attaatatgg
   139561 aaatatataa ctgcaaataa aaaacattgt agtaagatgt caataaatga acttgctatg
   139621 aaatgtaatg tgtctcgtgc aactattaca agatttgtta aaaaattaga tttaaaaggt
   139681 ttcagtgagt ttaaagtatt attaagctgg gaatcagaaa aggttcatgt catagaaaat
   139741 cagtcatttg atattgcatg taattcaata attaagtatg ttgaagatca aaaaaataaa
   139801 gattatgatg cattgtgtaa acttctttat gaatcaagaa caatatacgc ttatggttca
   139861 ggtgatattc aaaatgtggt tgcaaaacag ataaagagaa tgttcttatc atgtcaagaa
   139921 ataatatatg attttgaggg aagaacattt gatgattctt tttacaatat tgtcagtaaa
   139981 aatgatgtta tgattattat atctctaagt ggtgagaatg agaatacact taatattgct
   140041 agaagattaa aattaatagg aactaaaata atttcaatta cagagtttaa aaataataca
   140101 ttgactgatt taagtgatga atcaatttat atttcagcga ctaatatctc atttttacaa
   140161 atgcacccta gttataaatt gacaatgtta tattttatat tgattgagtt attatttatt
   140221 aaatatagta tttataaaag gcatagaatg attacagaag ggattgattg caaattgtag
   140281 tcattctttt tttttatgag aatttgaaca taaaaatgtg caaaaactta tttgactgtg
   140341 aataagctcc gaatgtactc taaagattgt atatatttat taacctgtta aaataataga
   140401 tatctaaggc caaagataaa ctaaaaatat gaggagggga gtaatttata tgatgaagaa
   140461 aatacagcgt tttggagggg caatgtttac accaacacta ttatttgctt ttgctgggat
   140521 aatggttgga ttctcaattg tatttcaaaa tcagtcaatt atgggttcac ttgctacacc
   140581 agaaaatatt tggtaccaat tttggggtgt aatatctagt ggagcttgga tggtatttaa
   140641 tcaattacca ttattatttg ctatttcttt accaatagca cttgcaaaaa agcaacaagc
   140701 aagagcttgt atggaggctt tagcaacgta tttgactttt aattattttg taggttctat
   140761 gttaagtttt tggggaaaaa gctttggagt tgatttcgca gctgaaataa gtgctggaag
   140821 tggacttgta agcattgctg gtattaaaac attagatact ggtatggttg gtgctttgtt
   140881 aatatcaggt attgtcattt atattcataa tagattttat gataaagaac taccagattt
   140941 tattggatta tttagaggct catcacttgt agttgcaatt tgtttctttg ttatgatacc
   141001 agttgcatta ttaacttgtt ttatttggcc tcatattcaa aatgttatta gacatttgca
   141061 aacgtttttt ataaatagtg gaaatatagg agtttggtgt tatgcattct tacaaaagat
   141121 tttaatacca actggattac atcattttgt atatgcacca atttgttatg atagtgttgt
   141181 tgttccgggt ggtacatcag tatattgggc tactcatatt caggattttc aaacttcagc
   141241 taagactcta aaggaaatgt atccaatcgg attttcatta tccggattat cgaaggtgtt
   141301 tggttcatta ggtgtatttg gtgctttcta tgtaactgca aagccagaaa aaaagaaaaa
   141361 agtattaggt ttaatgattc ctgctactct tactgcagta ttaactggaa ttactgagcc
   141421 attagaattt acatttttat ttgtagcacc acttttattc ctagtacatg catttttaga
   141481 tgcatgcttg caaacgattt cgtttgccct aggagttgtt ggtgattttg gtggaggaat
   141541 tattaactgg gttgtattaa attggcttcc tcttggaatg tatcactgga aggtatatgt
   141601 tgttcaagtt gttgtaggga ttatattttc atttatctgg ttctttgtat ttactttctt
   141661 aattaagaag tttgatatga aaactcctgg tagagaagaa gatagtgaag aaacaaagct
   141721 atatactaaa aatgaatact tagaaactaa agatgaaaaa ggaaataaat tgagtaaagc
   141781 ctctcaacaa gcatctgaat acataaaatt agttggtgga gcagaaaatg ttgtagatgt
   141841 tacaaactgt gctacgaggt tgagattaac cttgaaagat gactcaatta tttctaaaga
   141901 agaagatttt aaggcagtag gtgcacatgg tttagtgcat aatggaaaag ctattcagat
   141961 tattattggg ctttcagtac caagtgtaag agaagaattt gaaaatttat tataaaggag
   142021 aaggaaagat ggaaagaaaa agacagagga tactaattgc tggtgggggt agtacttata
   142081 ctgctggaat tgtaacaatg ttaattgaaa gtgttgctaa atttcctatt gaatcaatta
   142141 aattatatga taataatgat gagagacaaa gaaaagttgc tgaagcatgt gcaataattg
   142201 ttagagagaa aaatccagaa attaaattta gttatacaac aaatccagaa gaagcattta
   142261 ctgatattga ttttgtaatg gcacaaattc gtgttggttt atatgcttta cgtgaacaag
   142321 atgaaaaaat tccactaaaa tatggggttg ttggtcaaga aacttgtggg gcaggtggaa
   142381 ttgcctatgg attaagaaca ataggtccaa taatcgaaat gattgattat atggaaaaat
   142441 attctccaaa tgcttggatg cttaattatt caaatccagc agctatagtt gcagaagcat
   142501 gtcgtgtatt aagaccaaat tcaagaatta ttaatatttg tgatatgcca gtatgtttag
   142561 aggaaatatt tgctagagtt ttaggtttaa attctcgtaa agactttgat gttagatatt
   142621 atggattgaa tcatttcggg tggtggacaa gtattaagga caaagaagga aatgatttaa
   142681 tgcctgaatt acaagaatat tgtgctaaaa aaggatatga ggaatttaca cctcaaggtc
   142741 aacacaaaga atctagttgg ttagaaacta tgagagcagc aaaagactta ttagaaatag
   142801 aaccaactac attacctaat acttatttaa aatattattt aatggctgat gaaactgttg
   142861 aacatgctaa tccaaattat acaagagcaa atgaaattat ggatagaaga gaaaaggata
   142921 cattcgaaga atgtgaaaga attataaaaa atggcacagc aagagataca tggtttgatg
   142981 caagtgaaca ttctcaattt attgttgaat tagcttgtgc attagcattt aatactcagg
   143041 aaagattttt actgattgtt cctaataatg gagctattga aaattttgca gatgatgcaa
   143101 tggttgaaat tccttgcctt gttggaaaag atatggttga acctatgtct ataggtaaaa
   143161 ttccaacttt ccaaaaaggt ttaatggaac aacaagttgc ttctgaaaaa ttagctgtag
   143221 aagcatggat agaaaaaagt tatcaaaaat tatggcagtc gtttactatg agtaaaactg
   143281 ttccaagtgc aaaagtagca aaagaaatct tagatgaaat gattgtggct aataaggatt
   143341 tctggccaac ttttaaataa ggagaacaaa aacatgataa caaataaaat aaaaaatatc
   143401 acagcagtat taaaagatga aaatatattt ctttcagtgg ttatggtttg ttttctaata
   143461 ttacctgttt tatatatagt gtatttagaa ttgacatcat tatttacaaa tatttcattt
   143521 tcacaacttt taaacaatga tgttaatgca agtttaaatt taatctctaa ttttagtgca
   143581 gtatacagtg catatgttat ttacaatata aaaaagaata aagagataaa agaaaacatg
   143641 attgctttct atttagtctt attagggcag atattccaaa tttacacaat aactattgtt
   143701 atcatgttta cctatattta taaatttgtt ggaattaaac aaatcataag cagtattaaa
   143761 gaactacaat ggggaaagag ctataaggct cttttttcct caattgcagt atgcttaata
   143821 tcgttatttg taatgataat tagaataaag ttaattatgt agaggagtgt ctataatgtt
   143881 ctttaaaaga aaaaaagaag caattacaat taattcctac attgatggaa aaataattaa
   143941 tcttggagaa attcctgata aagtattttc aactaaggta atgggagatg gatttgctat
   144001 gatagcaaag gacaatattc ttaaatcacc gactaaagga gtaataagtt ttattgctca
   144061 aactaaccat gctataggaa ttaaattgca aaatgatgtt caaattctta ttcatattgg
   144121 attggatagt gcaacaacaa aaaaagaaaa ctttaaatta gaagttaaac aaggtcaaga
   144181 agttaatatg ggggaaaagt tagtagaaat tgataataag ttacttgaaa atactttata
   144241 tattccttta gttattgtag agaatcctaa tacggtaaaa tatcatcttt caaacttaaa
   144301 tcaggaagga aatagtggta ttaaagttat caattttgat tgattatgat taataaagcg
   144361 attaaattta aatttatcat attctatttt ttctcatata ttatttttgc ctttgcttca
   144421 acaaaattca cacctttctt atcaaaattg ggttactcag cgtttgaaag aggaattata
   144481 ttatcgagtt atgcaataac caatatatta tttcaattat tatttggagt attagctgat
   144541 aagtatcaaa caatgaaaaa aattgtttta attagtttat cagtttatgg aattgcatca
   144601 gttattatgt tttctactga atctgcaact tttataatat acttattact tgttgcttta
   144661 tcaggaggat tattaaatac ttgctgtagt ttatatgata catggataat aggttgtgga
   144721 gataatatta ataattattt gtcatttatt aagacttttg ggtcgattgg atgggctatt
   144781 ggaagtatgg tagcatctta cttgattctt agattctcat attttggatt atctgtagcg
   144841 attggtttaa ttgtagtatt acttattata aatatactat tattacctga tattgaaaag
   144901 attaataaga aaataaatgt aactaataaa gatattattg aattattaaa agataaaaaa
   144961 tatatcttac tagtatgtat tttattctta ttatactcaa tggtggtagc aaataactgt
   145021 actgtaatag ataaaatgat agctttaaat gctacaaatt ctcagatatc tttaaagtgg
   145081 tctttacagt cattgttaga gataccaaca tatctggctg gttcttattt attaaaaaaa
   145141 tatagcagtt taaacttatt aaaattaagt gctattatga taacagttca gtttctatta
   145201 tttgctttaa caaatgattc aaatatcatt attatactgt gtgtttttca agtgttttct
   145261 actcctttaa ttttaattac ttcaaaaaga ttaatatttg aagtttctcc taaaaaactt
   145321 agaagtagta gccaattaat agctttaagt atatttatgg gaggttcatc tctgattatt
   145381 ccaactgttg ctggtttttt gagcattaat attgggtata attatacatt aatggtatta
   145441 agtctttttg gatgcttagc ttattgcttg atagtcttat tgaattatct tcagtaataa
   145501 ttgttttaat atatagcagt aatatcactg tttatagcaa ctgtatttgc cacaatcaat
   145561 gtgtattttg gttttttata gagaagaatt attgtataga ttagaggctt cttaggagct
   145621 tcttttcttt gtttacacaa aaaagtgaag caagttttta ttttaagata tttctactat
   145681 aattataata gtcttccata tgttacaaaa gtgtaatgct aacagttaaa atgtaatatt
   145741 tacttaagga tttatttata taaaaccttt aaaataaata tatattaaaa aattagcaac
   145801 tggaggctat tattatgaaa gaaatattaa aaataaaaaa tatatcaaaa gattatggaa
   145861 taaaaggatt taaaacaaat gtgttaaaaa atatatctct tacagtcaat gaaggtgatt
   145921 ttatagcaat aatgggtcca tctggtgcag gaaagacaac attgctaaat ttaatgtcta
   145981 cacttgacaa acaaacttca ggagaaataa tactagatgg aattaatata tcaaaagtaa
   146041 aaaataatga actatcaaaa ttaagaagag aaaaaatagg gtttatattt caagactata
   146101 atctattaga caatatgaaa ctaatggaca atatagcact tcctctagca ttaggaaaaa
   146161 agaaaagcaa ggagatagaa gctaaggtat tttctatagc taaaaaattt ggattagaaa
   146221 atcatttaga taaatatcca tatcagttat caggaggaca aaaacaaaga ggcgcagcag
   146281 ctaggtcatt aattacaaat ccaacagtca tatttgctga tgagccaact ggtgctttag
   146341 actctaaatc agcatatgaa cttttagaat cattagaaaa aataaacaga gaaaataacg
   146401 ctactattat aatgattaca catgaccctc taacagcaag ttattcaaat gaagtatata
   146461 tgataaatga tggaaatata aagtgtaaat taaacaaagg aaatagtaga aaagaatttt
   146521 atggaaaaat tatggatatg ctagcctcta tgggaggtga gatgtaagtg agtatacttg
   146581 gaattgctta taataatttt aagagtaaca taagaactta tctagcattt tttatatcta
   146641 tggttttttc agtagttgtg ctaactaatt ttgaattatt aagatatggt gatgctataa
   146701 atgtgttaca agaggaaaat aaaaaattta cactatcagt gttagtagct gtaataatga
   146761 tactatcagt atttttattt ttctttatat ggtatgcaac aaatatattt tttaagaata
   146821 ggtctaaaga aattggaata ttgtctttta tgggattaga tttatatact ataggaaaaa
   146881 tatattttgt agaaaatatg cttataggaa taagttcttg tataacagga ataattatag
   146941 ggataataac atctagattt tttcaagtag tgataataaa gttatctgga tttaatataa
   147001 aggtatctaa tggacttagt atagaagcta tactatatgc tactttaatc tttatttcta
   147061 tatttataat aatggctgta aaaggtttta taacaatatg tagaagtagt gtaataaatc
   147121 taatcaatat atctaaaaaa caagaaaaaa taccaaaggt aggaataggt atatatatat
   147181 tagctatagt atcaattata gtaataggat atggctacta tctttctacc aatataagaa
   147241 ctggagatat aactagtgta ctacctgtta taggtataat aatagcaggt acttatggat
   147301 tattcaaatc agttatgcct gttatatttg atattataat caaaaataaa aaaatattat
   147361 ttaatggaaa taatataatt gcaataaaca atataaacta ccgattaaat aaaaactata
   147421 aaacttatgc tataatagct ataattataa ctacaacaat atcaactctt ggtgcttcag
   147481 ttgctatgaa gcatatacat aagaatgccc aagaacaaag aaatgtgtac actattagca
   147541 tagtttcaat ggataaagat gaagtgaata aaaaacaaat agagaatata ataaaagata
   147601 ctaataagat aaagtactca gtaaatccag aactaacaat tttaaagaaa acagatataa
   147661 aagaagctta tgatacaaca gatactataa tgaaatatag tgatttttgt aatactctta
   147721 aagtgaatgg caatgataaa gaattaaaag agtatggtga aagattagtt agtggaaata
   147781 atgtaataga gttaaaaagc cctcaaacga tagcatcaat agctacaaaa gaagccaaga
   147841 taaaacttga tggtcagtta tataatattt caaggggaga agtaaaagtt ccagtactag
   147901 ggacaggact taatcaaagt attatagtgg taaatgatga tacatatttt aaactaagag
   147961 ataagggtca acaagtgtat ttttatggtg caaaggtatt tcaagaagaa aatagtcaag
   148021 taatgttcaa caatattgaa aagaatttaa gtttaaaaaa tgggtatatt caaaatggat
   148081 ataaagctca aggtgagagt caatggatga agtttgcata tgtagtgctt gtatttttat
   148141 tcttagtctt tgcaattgta gctggaagta taatatatat gaaaatatat agtgatgcat
   148201 atgaagataa agagaaatat aagattttgt taaaaatagg tactacagaa aaagatataa
   148261 atagagctat acttaaagaa gtagctattt tttatacttt gccaatgtta agtgcaacta
   148321 tatctagtta ttttgcattg agattagcag gagatttatt gatgaccgat ttatttgata
   148381 tatatatact aagtttagtg atatgtttga taatattcgt aatatatgga gcagtatctg
   148441 ttaataagtt taagagtgta gtgtataaaa attagttgat atattaataa agagaaagga
   148501 gattcttgta ataagagtct ccttgttgat taactaaata atttgggtaa taaattcata
   148561 taaaatatgt tatgatatta ataattcata gcatagtgaa atattaggat aatggagaat
   148621 atacaaatgt atagaatttt attagtagag gacgatattg atttatcaaa agagattgcg
   148681 ttagcacttg aaaaatgggg atttaaagta gaattaattg atgattttga ggtagtatta
   148741 gatgaattta tagataaaaa accagatgta gtacttttag atgtaaattt accattatat
   148801 aatggatttt actggtgcga aaaaataaga gctatttcaa atgtaccatt aatattttta
   148861 tcatcaagag attctgatat ggatttaata atgggcataa ataatggagc agatgattac
   148921 attaccaaac cattttctat agaaatattg gttaccaaaa taaatggtat aataagaaga
   148981 gtctataatt atagtgattc taatagtatt ttgtattgtg aagatttgat gtttgatgtg
   149041 gggaaaggga ttataaaaca taagtataag gataaaagta tagagttgac taaaaacgaa
   149101 ataaaaattt taacattatt attaaaaaat aagaataggg ttgtatcaag ggaaagtctt
   149161 atgatgactc tatgggataa tgacgagttt gtgacagaca atgcacttac tgtaaatatg
   149221 aatagattga gaagtaaagt taaagaactg ggttttgatg attttataaa aactaagaag
   149281 gggataggat atataataca atgctagtaa aatatttgaa aggtaggtct aagtatattg
   149341 ctctaccttt agttgtagtt agtataataa atatctactt atttgctata gatattttta
   149401 aaaataaata ttcagagtta atatatttag attttttagt gctgtttata ataatggtat
   149461 tttttgttat agattatata aattttagaa atagttacac aaatttatat aattgtatag
   149521 aaaatagtgg tgaaatagat agttatttag ttgatggaca atcttttgaa gaaaatctaa
   149581 taaaagatat tatagaaaac ttaaaaataa aaaataatag tgacatagag acttataaac
   149641 aatcattaaa agaattggat gagtacatag ctaaatgggt tcatgaaata aaaattccaa
   149701 tatcttcttt aagtataatt acagataggt taagtagcat agaagatagt ttggatatta
   149761 agaatcaggt tgcaaagata aattttttag taaactctat tttgtatagt agtagaagca
   149821 acactatgtt tgaagatgta tttataaata aatttaattt agaaaaattg gtaaaaatgt
   149881 ctataaaaaa taattcattt ttgcttataa aaaataatgt agaagttagt ttgaatgaat
   149941 tagaaaatga tgtttacaca gattctaaat gcatgtcata tgttttagac caaattatta
   150001 ataatgctat aaagtattca aaggaagttg gtaagattga atttaattca aaaaagttag
   150061 aaaatggagt ggtattatct ataaaagatt ttggtatagg tataaatgag gaagatatat
   150121 ctagggtttt tgacaaggga tttacgggga aaaatggaag aaatcaattg tataagtcta
   150181 ctggaatggg gatgtatttt gtaaagaaaa tgatagatag tttagggcat gagattgagg
   150241 tatgttcgaa aattggttca tatacaattt ttaatatcta cttttatgat atatcggatt
   150301 atttaagcct agatagttag gttattagac tataaaatct atcatcatat acaaatcgac
   150361 atatacaata agaataaatt tagttcttga aaatagtgaa gatttaatta gtgccttaaa
   150421 tgatgctcta tctatattat aaaataataa ttattatata tgaaaaacat atcagatagg
   150481 tacctggtat gttttttatt tgtagtaact attttaatat ggtttttgga gagagaatat
   150541 gttttgttta tgaaaaaaaa ttacatggta ttacattgac actgaaaata aattaatgta
   150601 agatttagct aaggtaaaaa acgtgtataa gattaactcg attaatttcg taagagtaaa
   150661 ttatcgtaat taaagatgaa ataagattaa ttctaaaatt attaaactta ataccttgat
   150721 ttggggagga ataactataa acttaaaagg atgataacta tgtatagtgt aggtttaatg
   150781 tcaggaactt ccttagatgg agttgatgca gtactagctg aaattagtgg gaatggtaga
   150841 aatactaaag ttaagcaaat agaatttata actctagaaa ttcctaaaga tataaaagac
   150901 gaaataagaa agtgctgtat agaagaggaa tcgagtgttg atttaatctg tagcttaaat
   150961 tttaagcttg gatatttatt tagtaaagct gtaaaatcag tgtgtcataa agcaaacttt
   151021 catatagcaa atttggattt tatcgcatct catggtcaaa caatctttca tataccaaga
   151081 agttataata attttgtatc ttcaacgctt caaataggtg aaccagcagt tatagcatat
   151141 gaaacaaata caaaggtaat atctaatttt agagtaatgg atatagcagc aggtggagaa
   151201 ggtgctccat tagtaccata tagtgaattt ttattatata gtgataacaa taaaaattta
   151261 gcacttcaaa atattggtgg aataggaaat attactataa tacctaaatc atgtaacata
   151321 gatgatgtat ttgcatttga tacaggacca ggaaatatga taatagatgg agtatgtcaa
   151381 agattattta atagaaagta tgataaaaat ggatactttg catcaaaagg taaaattaat
   151441 gaagaaatgt taaaagattt gatgagtcat aagtatctta gtcaagcgcc acctaaaagc
   151501 actggaagag aggtatttgg acaagtttat ttggataaca tgcttaacaa atataaacat
   151561 gtagataaat atgatttgat agcaacagta actatgttta cggcaaaagc tatatattat
   151621 aattataaaa acttcatact tccaaaggtt aatgtagata ctttattaat tggaggtgga
   151681 ggagctcata atctaacttt aataggatat ataaaagagt tattattaga ggttgcagta
   151741 ttaactcaag atgaatatgg gtattcttct gatgcaaagg aggctttggc atttgtaatc
   151801 ttgggcaatg aaacattaaa taattctttt tctaatgtaa tatctgcaac aggggctaaa
   151861 aataaagtta ttttagggaa tataacacct aaaccttttg gaggtaaatg acatgtctaa
   151921 taataaaaaa aagaaaagaa agaaaaataa taattataaa aatgcaaaaa gtacaaaaag
   151981 taataaaaat actaagaaac aaatggagaa aaatcaaaga acagattata atattccaac
   152041 tataagtttt aaaagtggat taatattaat agtttcatct cttgtaagta ctgtagtttt
   152101 tcctttgtta ttatctatat ttggaataga taatagattt ggagttgtta taggaaattc
   152161 attaattaca tcttttgcag ttgcatatac aagatacttt gttgaaacta agagaggttt
   152221 ttctttggga ttttttagac tgtatatttt atttgcttta tcatttgcaa taataggtta
   152281 cttctggata tataaaggaa tacatattta aaaaagtatt gagactattt tatgttaata
   152341 ataagatagt cttttttctt ttttaagaaa agatatgagt attttaagta gtgtgtaatt
   152401 ttagacaaaa gaatgattag ataaataaag caattaaagc aagatataaa ttcatgaaat
   152461 aaaattacaa ataaaaattt aaaatatgaa aaaatatata caaacgtatt cctgtaatca
   152521 aaaatacatg ctataatgat tgaaaagaaa taaaaaaaca gggggaatca atatgagagt
   152581 attatttgtt tgttcatcag ggatgtcaag tgctatagca gttaatgcat tacaaaaaga
   152641 aggagcaaaa aatggaatag atatagatgt tttggctgtt ggtactcaag agtttgagga
   152701 tgaagttaaa aatggatggg atattgctat ggtagctcca caagtcagac atagatttga
   152761 ctatttaaaa gcttttgctg atgaggttag tgtaccatgt gcattaatac aagcacaagc
   152821 ttatagtcca ttaggaggat caaagttatt aaaacaagtt caagagctgt tgagtaaata
   152881 gtagttgcag tgttgttagg ttagaagaaa gttgatttta taaaaatttt aatgataata
   152941 aaaataaata ttaattaagg agagaaaaga tgctagataa atttacagaa tttttagaca
   153001 ctaaattatc aacttctatg gccagattgg cagaacaacg tcacttaaga gctgtaagag
   153061 atggaatcgt agcttcatta ccacttataa tagttgggtc atttttcttg atattagcat
   153121 ttcctccatt accagattca tggggggtaa ctcagtatct aaaggaaaat gcagttacaa
   153181 tattactacc atatagaatg acatttttta ttatatcagt atattctaca tttggcatag
   153241 gttatagttt ggcaaagtca tataagttag atggattgac aggaggttta ttagctacag
   153301 ctacattact tttgacaata gttcctactg caatagaggg tcttacccct gatttattaa
   153361 agatagttga aaagagtcca gaacttttag cttggtataa ttcaattcct caaggatggc
   153421 aaatgccaat ggctaatctt ggtggaggtt caatgtttgt tgctattgta acatctataa
   153481 taggtgttga gatttataga tttactgaca aatctaaatt caagataacc atgccagaag
   153541 cagttccagc atcagtcaca aggtcttttg aagctctgac accagccgca ttaataataa
   153601 ttttaatggc tattgttact tatttcctag ggtttgattg gcatggcttc atagctaaat
   153661 tagtaactcc attagtttca gccactgaca cattaccatc agtaattata ctaatatttt
   153721 taataacgtt tttttggtca tttggaatac atggtgtatc aataataggt tcattggcaa
   153781 gacctttatg gatacaatta ttagatgcta atacagcttc atatgctgcg ggtcaagcag
   153841 ttccaggtat tgctgctgaa cccttttttc aatggtttat atggattgga ggttctggag
   153901 ctacaatagg cttagcttta cttcttgcat ttagagcaaa atcagcttat ggaaagtctt
   153961 taggaaaagc aactgtaata ccagcaatat tcaatataaa tgaaccaata atatttggag
   154021 caccaatagt attaaaccca atattaataa taccatttgt tgtggcacca atagtaatgg
   154081 caacagtttc atggtttgct atgagtgcta atttagtatc cagagtagta gttactgctc
   154141 cttggacatt accaggacca gtaggggcat atttagccac tggtggagat tggagagctt
   154201 cagttcttaa cttattatgt atagctatat caataataat ttactatcca tttgtcaaga
   154261 tgtacgataa gaggttgctt catgaagaaa aagttgaaga gcaagaagct tattaattag
   154321 aaactatatt ggaaattaaa aactatatta gattagtata aatttcaaag tataacagtt
   154381 atgaaataag taacgaagat attttgttga ttgtttataa aaaaagaaaa ggtaaacttt
   154441 tcttttttta taaatatata tgaaactttt tttcatcaaa tttttaaaaa agtttcgtgt
   154501 aattcgaaat aaatttaaac acatatagga tataaggaga tgacacagat gggaagatta
   154561 ggaatatcaa tttatccaga aaaaacaaca tctaaggaaa tatatgatta tatagataaa
   154621 gctgctgaaa atggatttac acgtatattt tcatgtttat tatcagttaa agatactaaa
   154681 gaaaatataa ttaaaaaatt taaaagtata aatgaatacg ctaagtttaa aggttttgag
   154741 gtaatacttg atgtaaatcc cagagtattt ggtgaattag aaataagcta caaagatttg
   154801 aattttttta aaaagacgaa ggcagacgga ataaggcttg atatgggatt tacaggttct
   154861 gaagaggcat taatgacttt taatcctcaa aatcttaaaa tagaaatcaa tatgagtaat
   154921 aatactaatt atatagatac aataatggac taccaaccaa ataaagaaaa tttgatagga
   154981 tgtcataact tttatccaca tagatatagt ggattaaatt tagaacactt tataaaatgt
   155041 acagaaagat ttaataagta tggattaaga acagcagttt ttgtaacaag tcaaaatgaa
   155101 actacatttg gaccatggcc tgtaactgat gggcttccaa caattgagat gcacagaaat
   155161 atacctatag atattcaagt aaagcatata atagctatga ataatataaa tgatataata
   155221 atatcaaatt gttatccaac atatgaggag ctaaaggtat taggttctat gagaaaagat
   155281 atggttacat ttgatgtagc aatagaggaa aatatacgag aagttgagaa gaagatactc
   155341 tttgaagaaa tacattttaa tagaggggac atatctgata gtctgataag gtctactcaa
   155401 tctcgtgtta aatataaagg atacaaattt gaactattta atactcctaa aataataaaa
   155461 agaggagata tagtaattga aagtagtgaa tatggtcatt atgcagggga gttacaaata
   155521 gccttgactg atatgaaaaa cagtggtaaa tcgaatgtag taggatatat aagaaaagaa
   155581 gaattattta tattagatta tattaaacca tggcaaaagt ttaattttaa accctcaaca
   155641 aaataattta ttatgaaaat attaatttat tataaaaata taattatgaa agttggaatt
   155701 aaaatgtgtt taaaaattta atattaagaa aatgaggaaa tgatatgtta ataaaaactt
   155761 tagaaaattt agttacagaa ggtagaaata agaatacatt gcaaatagat aaagaagata
   155821 cattaggcat aatagaatta ataaataacg aagataaaac tgtagcctat gctgttgaag
   155881 aacaaaagga gagtatagca aaagctgtta atataatagt agatagaatg aaacagggag
   155941 gtagattatt ctatatagga gcaggtacca gtgggaggat aggaatacta gatgccacag
   156001 aatgtcctcc aacttacgga gtggattttg agcttgttca agctataata gctggtggaa
   156061 atcaagcaat atttaaagca atagaaggtg ctgaagatga taaagaactt ggaaagcaag
   156121 atataataga tagaggagtt acatctaagg atgttatatg tggtatagct gcatcaggaa
   156181 ggactcctta tgttataggt gcaatggagt atgctaagga attggggtgt gcagtactat
   156241 caataactat gaatccgaat agtgaaatga gtaaaaaagc ggatttacca ataaacatta
   156301 tagtaggggc agaagtaata atgggttcaa ctagaatgaa aagtggtaca gctcaaaaaa
   156361 tggtatgtaa tatgttaaca acagcttcta tggttaagat gggaaaagta tactcaaact
   156421 tgatggtaga tgttaagaca tcaaatgaaa agttggttga aagagcaaaa agaataataa
   156481 tgatagctac aaatgtaaaa tatgatgttg cagaaaaatt cttagaagaa gcagataata
   156541 gcgttaaatt ggctatattt atgataaaaa gtggtttaga taaggatagt gcaaagagta
   156601 tcctagatag acaagaaggt tatataagtg aagctttaaa atcaatagaa aaattgtaaa
   156661 ataaataata gtactgataa cctttcaata ttaaaaaaac agcattggaa ggttattttt
   156721 agatattaag tattgaaaga attattaaag atattgtagg aggatagtat gtatttttta
   156781 ggtgtagatg gtggaggaac gaaaacaaca tttacattag tagatgaaga attaaatata
   156841 gtaggaacca taaccaaagg aacttgtcat tataatcaaa taggatttga taatctaacg
   156901 aaattattaa taactgggtt ggaagaagtt tgtaaagatg ctaagataaa tgtagaagaa
   156961 ataacgtatg catttgttgg acttgctgga tatggaaaaa taaaagaagt attgtatgca
   157021 ttagaagtag caacaaaaaa tgcatatagt catataaatt atactctagg taatgatgta
   157081 gaaatagcat tagcaggttc tttaaatggg gaaaaaggta taaatataat tgcaggtact
   157141 ggttcaatag cacaggcttt agataaagat gggaatcttc acagatgtgg aggatggggc
   157201 tatgtattag gagatgaagg ttcagcgtat tatataggaa tggctacctt aaaaatgttc
   157261 acaatgcagt ctgatggaag gtgttcaaaa acaaaattat atgatttaat aaaaagacat
   157321 cttaatatag agaatgatta tgacataata aaatatgtaa atgatgaaat acaaggagat
   157381 agaatagaaa tagcaaagtt tgctacgata tgtttaaaag cagttattga aggtgataat
   157441 actgctagta aaatatttga tgatgcagct tatgaattaa gtaggcttat aataggatta
   157501 gagcatcatt ttgaacaagg tacaaagata aaggtatctt attcaggtgg agtgtttaag
   157561 tcaggagatt taatattaga gccacttaaa aaatatttga ataaaacgag atttggtata
   157621 gtgagaccag tgttgactcc agatttagga gcatgtttac ttgctaagaa gaaatattat
   157681 agtaaatagg tagaggtgat agagtatgag ttgcatttta aaattaaaac agatatatga
   157741 agatttaacg gaagtagata aaaaaatagc tgattacata cttaataata cagaggctat
   157801 aagtaagctt tctgtatcag aattggcgtc aaactcaaaa acaagtacag caagtatagt
   157861 taggttttct agaaaaatgg gatattcggg ttttggggat ttaaaaattg agatagctaa
   157921 agatttgatg ggcaaagaaa atgaatacac atatgtagat gaaaactatg attgtaatat
   157981 agatagtgtt ataaacaaaa ttacaaacaa aaacatagag actatcaacc aaacaaggtt
   158041 gttgaatgaa aaagatataa taaaagaagc agttgaacag ataataaagg ctaaaaatgt
   158101 atatatattt ggagtaggtg gttcggcttt agttgcacta gatttacaga tgaaactttt
   158161 aaggataaat aaacaggcat ttacctcttt agatagtcat acacaactta tggtatcttc
   158221 aaatgtagat aaagaagata tagctatagc aatatcttac tctggagaat caaaagaagt
   158281 aataaagtct atagaaaatg caaaattaaa aggatgtaag gtcatttgta taactaaata
   158341 tagtgacaat catcttagta agattagtga tttaaagcta gtagtaccaa atatagaaaa
   158401 aagacttaga gaaggagcta tttcttcaag aatagcaatg cttacgttga tagatataat
   158461 atatatttct ataattcaag aaaacttaaa tgaggcagaa cagaaactac aagaaacaaa
   158521 aaggatactt gattatttaa atattaataa tgcttaaaac taggttatat atcaactaaa
   158581 caaataagtt aggctataag cgtaagtcaa taagaaatag ataaatatct aaaatattga
   158641 cttacttaat aataatatat agcattttta taatacaaat gagttgtctt aaaattgatt
   158701 ttttttaatc aaattttaag ttcaactcct tttttatatt tttatagata tatctatatt
   158761 ttcccagaaa acgtattgaa tatacaaatt ataagaagta taatgttgtt gggagagaat
   158821 gtatgaaatg tatacaaagt tgattttaac tgtattattg ataattctct ttactcttac
   158881 cattattaat gattgaagac aatggtattt attataggtc aaagattccg aatgtattaa
   158941 tcatcatcat tttctcaaac taacagcaaa caccctgatt tgcgagttgt attgtataca
   159001 aattatctag aaaatatcta ttagattttc catgaaattt aaatatttca cgaatgtatg
   159061 aatggagaaa tatacatgtt gacaatccac ctttttaaat cctaaattaa ttttattaat
   159121 ggtagagaat aggaagtaac aatgttttat aaaggagaat attaagtatg aagaaaatta
   159181 ggaagttagc taccaagtta ttgattacaa caatagtttt aatctcaggt atgagtatga
   159241 cagtttatgg tatgacagcc aaagaggtaa cagcaaaaac accaaaaagc tatgtcactg
   159301 gaaccaatag cgtatatggt ccaaagctgt cacaagccca actaaactca gtagcacaag
   159361 caacagcaga ttttatgaac aagaaaatca caaagaatat gaccacagat gctaagattt
   159421 tagttgccta caatcacatt aaaaataaca caacatatgt tgactggaat gcagtagagg
   159481 gagcaaatac tgcctataca ttggttacta aaaaaggtgc atgctcagga atggctagga
   159541 gcatgaaagc tttgtgtgat gctatgggaa ttgaatctta ttatgtacac agcacatcaa
   159601 atgaccacca gtggaatctt atccgttttg gtgatgggcg tttgtatcat gtagatattg
   159661 atgctaataa atcagcagga aaggatatca tatacaagag tcttagccac ccattaccat
   159721 ttgataagac agcatatcca aaagttggtg caatagtaca gacggtaaaa ccagaacaga
   159781 cacagaaacc agcaccacct ggaaagcaca ctatgttacc acatcaagaa ggggcaaagg
   159841 ctgttggaaa ttttggaaaa aaaggagaag atataaatga aaaacatgta atgtatgaag
   159901 gtgttagatg tagtgtagtt aattcatcag taaatacaat tacatttaca ggtagtgaat
   159961 caaatttaga cccatcaaat cttacgattg ctgtaatagg atttatgaac acaccatatg
   160021 ggatgtttgc attagcacca gagggtaaac ctgttgaata tccttttaaa tatgataagc
   160081 cattttcttt agattttagt ggtaaaaatc gttctggtgc agaattagcg aagtactgta
   160141 aaaaaaatga tgtgactatt aaaatagaaa tcactgatga aaaagctaat attggacttg
   160201 gtcaaataat gtatgttcga tatgaataat gatttaatca tgacagtaga ataagttata
   160261 aacattgcgc cctcttacta ggggcgcatt taatattata tctgatattt tgtagtcagg
   160321 tcaactgcta gatttctccc ctttttattt ataaaaatta ttatctctaa gcatctgagc
   160381 atgtttacga ttaactaaaa actgttttaa ctcagtcaag cataggaata aaatagctct
   160441 attttcaaac tctgttctgt caacaggcag aggctggttt ttcatactaa gcattagtct
   160501 ctttaattct tcaagaagaa gattgcctgt ttcagcttca aattcagtat aacctatctt
   160561 atgtataaaa gcagatagaa tatgagcttg tggtggtgta gaatttagtt gagatacata
   160621 actatacaaa ttttctaaga tatcccgttg gctttttata atatccatat gttctaagaa
   160681 gaatctagta tcacttaata aagtattatt aatattatcg taagtttcag aaatactgct
   160741 gtcaataagt gaatttaatg tatataaatc tctactatat ccattttctt ttttaggatt
   160801 tacaataata tctgcaatgt ctataagtac aatactcact tcttcctgta actttttttg
   160861 aacttcatgg attttatgta tatttgttgg aatatacata tttattaaga cacctattcc
   160921 agttcctact gcaaatattc cagcttcatt taaaatccat ttgatagaag tttctccttg
   160981 aaggtagtaa tgggatgcta tgactacaca catagcaata acatcttgaa tatttaacaa
   161041 aaaacaaagt ggtataatta taaatataaa tattgaaaat gaagtcaaat tatatcctaa
   161101 aatattaaaa cataaatatg aaaaaatagt acataaaaga aaaccataaa tctttccaat
   161161 ggagccttta agagtttctc ttttagtgtc ctttactgta agtagtacta taactccagc
   161221 aaccattgaa tattctaatt ttaatagcca agcaataaat atagcaagag aacatccaag
   161281 agataatttt attactttaa gtgaattaat attattcaaa tgcaaacctc ctgtaaatca
   161341 atataataaa attctaacat aaaactaata ttgcttgaaa ggtaagtaac tatacttaat
   161401 tattttattg ccctatttgt ttagatacaa tcaatataat tttattttat gaaaattttt
   161461 tgtaaaattt taaatttaga gactaacatg agaccacaaa gaggaagttt attataggaa
   161521 gaaaacttaa aattgatttt aagcagcaaa tgaaaataat caaatatgta tatactatta
   161581 ttaaaaaata aaattatata gttaatatga ttttataatt ggtttagtat agagattttt
   161641 aacttttatg ttatactatt tataaaagta ggtataaaga ttaaaataca taatcaaata
   161701 tgtataagag gttttaaata gtattgttaa tgaacttgat tattgtttat aattacaaat
   161761 tggaggagat aaacatgaaa attactgaag gatatatgcc ttttaaaggt tttaaaacgt
   161821 attaccgtat agtaggagaa aatacggaag ggaagaagcc attagtatta cttcatggag
   161881 gtccaggttc tacacacaac tattttgagg tattggataa gatagctgaa agtggtagac
   161941 aagtaataat gtatgaccaa attggttgtg gaaattcatt tgtagaaggg catcctgagc
   162001 tatttaatgc agatacttgg atagaggagc ttattgaact aagaaaacat ctaggacttg
   162061 atgaaattca tctgttaggt caatcttggg gaggtatgca ggctatttgg tatgctattg
   162121 aatataaacc aaaaggtatt aagtcttaca tcctttcatc tactctttct tctgcaaaac
   162181 tttgggagaa agaacaaaaa agaagaatat catatatgag tgaggctgac caaaaagcat
   162241 tacttgatgc agtaaatact ggagattact ctagcaaaga atataatgat gcattagaaa
   162301 gatttatgga aatgtattgt gcaggtgaag tgacagaaga ttctccagag tgcctgagaa
   162361 gacctaaaaa atcaggttct gaagcatata ttgtaggatg gggacaaaat gaattttctc
   162421 ctacaggaac tctttctgga tatgaattta cagatagatt acatgaaata aaagagcctt
   162481 gtctagtaac tagtggagca atagatttat gttcaccata tattgcaaag actatgtatg
   162541 atagaatacc taatagtaag tgggaattat ttgagtattc aagacatatg ccattcgttg
   162601 aagaaaatga gaaatatata aaagtcttaa ctgagtggtt gaatgcgaac gattaaaaac
   162661 tatataaatt tatataaaaa aatgagtgtc tcaaaatgaa ctttttagtt cattaggcac
   162721 tctttttgca tgaaatcaaa tatattttca ttatttgaac gataaaatga ggcttatatc
   162781 tattttggga aagtaatttt ttattactag cgttagattc taatctaatt gtatacttat
   162841 tgaaataata gaaatatatt ggtgtttata acttaatttt attgtttttt agaaattttt
   162901 ttatatattg gtataattat tctgtttaaa tttgattaaa aagtatatta attataataa
   162961 gaaacaatta tataaatagg aatagattat tataattaat atagatataa aaataattat
   163021 agaaggaaag gcacattatg gaaaaattga gagttattga aatgataaaa aataatccca
   163081 atattatagc tacaatagat aatccaactg atgaaatgaa attgttagct attaaagaaa
   163141 atgggcttgt actagaatat ataaataatc caaccagaga gatgcaagaa ctagcaatag
   163201 ataataatat tagagcaatt aaatttatag ataatccaac agaagatatg atgataaaag
   163261 cagtaaatga gggatggagt atactggatt atatcaaaaa cccaactgat aaagttattg
   163321 aaatggctat aaatcaagca ggatgggcaa ttaaatatgc taaaaatcca agtgaagaat
   163381 tacaactgtt agcagtaaga aaaaattatg attcgataaa gtttataaaa caaccttatg
   163441 aaagtgtaca agaggaggca gtgagaataa gttatgatgc cttgagatat atagattcac
   163501 ctagttataa tgcagaactt atagctataa aaaataatga agcagctatt agctttataa
   163561 ctgatttaga taaaaataaa atattggaat ttttaaaagt gaatatttta gtgattaagt
   163621 acattctgaa aaaagtatct aaagatgaat tagagagtgt attaaaagaa gtattatcca
   163681 aagaagatgt tgaggaaaag tatattagag attttttgaa ttgtagtgtt atagatagaa
   163741 atagtgaaag tataccaata gataaaatta tgtttattta taaatatgga agtaagacag
   163801 caaaaaaaat agctgtagat gagaaattaa agattatgta ggagagagaa aaatgaattt
   163861 tatagacaca ttaaaaagcg ttgacttaat attatccact ggagaagtac ctttaatagt
   163921 aggtgaaagt ggaataggaa aaacagcttt agcaaataag cttgccaaag aaaatgattg
   163981 gagtttaatt gttattgatg gaaacttact taaagagggt gaaataggtg gtcttccaac
   164041 tatagaatct tatgtaggag ttaattctaa tggatataag actgaaaaga aaacaacagt
   164101 gtatgctgtt cataacaaat taagagaaat tgatgaagag atatctagaa gtaagacagt
   164161 tcttttattt atagatgaga taaatcgttg tgagcataca gtacagcaag aacttatgaa
   164221 tttaatttta aatagagaaa ttaatggata taaactgcat gatgatgtaa agattttagc
   164281 agcaatgaat ccatcaagta aatatggttc agattttgat tatcaagtgg tagatatgga
   164341 tgcagcccaa gaaaataggt ttgtttggtt aaatatggag agtgaccata cacaatggat
   164401 aaaatgggca atagatgagg gtattgaaag aaaagttatc gagtttattt ccacttttcc
   164461 agaatatctg cataaaataa atgaagatga tgtaagagct actcctagaa gttatgagag
   164521 agtatctaaa atttataaag tttataaaga aaaaaataat tctattccta gagcagtatt
   164581 tttaaatgtt gtaaagggta atgtaggtaa agttattgca gaagaattta taagttttat
   164641 tgaatcaaac tctgaaccat taatatccta tgaagatgtt tttttaggag aatctattga
   164701 tgagtctatt gtagaaagag taaaaaatga gagtcataca agactttatc tatcagctat
   164761 gaacattcta aaagacttag aattaaatat taagaatgat aaatatgaat caaaccacta
   164821 tattaataga tttattgaat ttttaaaaat gtatcctgta gatttaatga taggtattat
   164881 gaaggatatt agaaacagtt atattgaagt atataaaaaa gctatagaaa atgaagagtt
   164941 tgtaaaatca tattttgaat cttatagttt aataagggga taatgtatgg aaaattattt
   165001 tgataaacaa gcaaaagagc tttataataa agcaagtgaa attataaata ctcattctat
   165061 gctaaaggca aatcgtgcta atgagaaatt tgatatagat ataccacaag attttaagta
   165121 tgagtttttt agtcttgtag ataaagtgaa tttaagtctt atggaagaag aagataattt
   165181 ttatggatat tttttgtttc agatgtcaag agaaataaga tttgatataa gtagtcctac
   165241 aggtgtgaat tttaagggag ctaaatatgt tatatatttt aatccaataa tctttttaac
   165301 gcttgacata aagcaaatgg agactacaat taaacatgaa attcatcata tattatctat
   165361 gcatttgatg agagcaaagg agttaaaagg aaagtatagt acattagcaa ttaatatggc
   165421 aatggatata gtagtaaata aatttctaaa caatttacca ccatatgcaa ctaccttaga
   165481 gtgggtaaat ttaaagtatt ccttaaaact tgaaccatat gaaccttttg aatattatgt
   165541 agaaaagatt cagactgaat tagatttgat ggaagtggat gaagatggtg aggaagatga
   165601 tagtgataaa tatggagata tagaaattga ttatagcccc gaaagaactc atgatatatg
   165661 ggatgaatcc aatgagatag atgaaaatac ccttagagaa tttactgaaa aatttattaa
   165721 cagttctcaa aaaggtaaag ttcctgctta tttagaaagt atgatatcat cacttaaaaa
   165781 tagtaagggg gaattgccat ggaatttata tcttaataga ataatgggaa cagttgaaaa
   165841 taataaaaag aagactataa caagaagaaa tagaagacaa ccaaatcgtt tagatttgag
   165901 gggagaactt agaagtcata aggcagaaat agcagttgca cttgatgtaa gtggaagtat
   165961 tagtgatgaa gagtttaaac aagctattaa agaagttctt agtatagtga aaaactataa
   166021 tcatgaaatt acaattatag aatgtgataa tgaaattaga cgtgtatata aagtgagaac
   166081 tgaaaaagat ataaaagata gaattaggat aggtggaggt actagatttt ctccagtctt
   166141 tgagtatgct aataataaaa agattaattt gttagtctac tttactgatg gtaaaggtga
   166201 aaataaacta caagtaatac ctagagggta taaaatttta tgggttattt ctggaagagg
   166261 agataaaatt tcattaaaag aaccttatgg agcagttaaa aaacttacta aggttaaaac
   166321 aaatgatgaa atattagaaa taaatgatgt aagaaatgat gggtactcaa tgaatagcca
   166381 agcaccaatt ttataggtat tcacaggaga taagctgtat taatttattt tgatatgctt
   166441 gttataaaaa tctaaaaaat acattaatca atggttaatg tattttttaa ttttaataat
   166501 ataagtttta cttacattta agtctcaaaa tgtgttaaaa tataatatat agcagatagt
   166561 tttggcaagg tggatttagt tgtcaaaact atttttttta ttaaggatgg tgatgttttt
   166621 gtttaagatt gatgattata taatgtatgg tatgacagga gtctgcaaag tcatggatat
   166681 aacaaatgaa cgatttacaa atggaataaa aaaagagtat tatgtattga gtcctattta
   166741 ttctaataat acagtaataa aaattcctgt agataatgaa aaagtaccaa tgagaaagtt
   166801 actttctaaa attaatgtgc tttcattaat aaatgatatt cctaatatgg atacatcatg
   166861 gatagataat gaaaaattga gaagtgagca atttaaaaaa atactcagag gtggtaaatg
   166921 tgaagagtta ataaaattag taagaagtat agataataac agagagtatg taaaatctat
   166981 tggtaaaaaa acacatcaag cagatgataa tataatgaaa gaagctgaaa ggttattaaa
   167041 tgaagaattt gcaactattt tagatatttc tcctaatgaa gttagttcat atatttcaag
   167101 tcatatacct caataaagtg ttttagtatc ctttatttaa tctattttaa gtattattta
   167161 tgtatgctgg ttttggtaaa ataaaatata taattaaatt atataaaaaa taataatgat
   167221 tgtattgaag aattacagaa tagtgcggag agcctactcc tttaggtgtg agatggatat
   167281 cacttaaaga tttaaattgt tattgtagat gtttttaata taaaacaaga ttaataagtg
   167341 tattgtaagc tttaagtgaa attgatacta taatgagtta cttagatttt aaaatatata
   167401 atattataaa aaatcctttt aggttttgaa tgaataagat ggatactatg ttgaatagaa
   167461 tccatcttat ttaagtttta tttatgttgt ttatttgtaa gcattatttt tgtacatgaa
   167521 aacacagtgt aaaaatatgc ttagaattat gaagttttat taaaaagata ttcgacaaaa
   167581 taagactaaa aatgttctta aacttataac taagataaat attgtatatt tatagtgtag
   167641 cctgaaaaat tgtggatgta cgaaatttat ttagtatttt attgaaacaa agtagaagaa
   167701 gtactatagt ttatctttga atagattgtt attttttagt gaaaaagtta ttaggttaat
   167761 acataaatat aatagcttat aaatagttta agcatgttaa aaaagtagtt attagagata
   167821 tatagttaca ttgcttataa gatacttaaa atgatagcat tcacttatat ttagaaaatt
   167881 aagataaaaa atcattttta ta
//
LOCUS       DAEORM030000003       114334 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.003, whole genome shotgun sequence.
ACCESSION   DAEORM030000003 DAEORM030000000
VERSION     DAEORM030000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 114334)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 114334)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 114334)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..114334
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.003"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            complement(175..1254)
                     /gene="htrA"
                     /locus_tag="KRH23_000311"
     CDS             complement(175..1254)
                     /gene="htrA"
                     /locus_tag="KRH23_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease HtrA"
                     /protein_id="HHS5223610.1"
                     /translation="MSRRKKGISLVILVAIISSILSSFLTIILVKDNLVSKSTGSSTP
                     IVVNDDGKSQNIYQAVAEKATPSVVGITTTSVDTSNMFAIPTETQGVGTGIIVDSNGY
                     ILTNSHVISDGQATSVNVLFNDGSTTSGKVVWFDQQLDLAIVKVDKTGLTPAEFADSD
                     KVKVGDISIAIGNPLGLDFQKTVTQGIISGLDRTIQTEKTNMTGLLQTDASINAGNSG
                     GPLLNQKGQVIGINTAKASQAEGLGFAIPINTAKSIVEEVIKNGKYEKVTLGIKGTDV
                     SNYEAATGTKLSTDKGVYVAEVISGSSAEKAGVKVGDIITKVGDTDITGMNDLNKKLY
                     TFSKGASTKITVNRGGKAVTINVNF"
     gene            complement(1410..2759)
                     /locus_tag="KRH23_000312"
     CDS             complement(1410..2759)
                     /locus_tag="KRH23_000312"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004347 - glucose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HHS5223611.1"
                     /translation="MGKINFDYSKATEFFCQNEIDVMQPYVDVAHDMLHNKTGLGNTF
                     LGWIDLPKNYDKEEFDRIKKSADKIKSDSDVLLVIGIGGSYLGSRAAIDMVSHSFRNG
                     LKKEQRKAPEVYFVGHNISSTYIMDLLDIIEGKDISVNVISKSGTTTEPALAFRIFKD
                     YLEKKYGKEEARKRIYATTDASKGALRQLATEEGYETFVIPDDVGGRFSVLTAVGLLP
                     IAAAGLDIDAMMKGANDAREAFQNPDLKSNDSYRYAVARTILHRKGKDVELLVNYEPQ
                     LHYVSEWWKQLYGESEGKENKGLFPASVDFSTDLHSMGQYIQDGKRLLFETVLNVENC
                     KRNITISSEEVDLDGLNYLAGKTVDFVNHKAFEGTLLAHTDGKVPNLVINIPQLDEYN
                     FGYLVYFFEKACGISGYLLGVNPFDQPGVEAYKKNMFALLGKPGYEKEKEELEKRLK"
     gene            complement(3024..4652)
                     /locus_tag="KRH23_000313"
     CDS             complement(3024..4652)
                     /locus_tag="KRH23_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0005436 - sodium:phosphate symporter
                     activity [Evidence IEA];
                     GO_process: GO:0044341 - sodium-dependent phosphate
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HHS5223612.1"
                     /translation="MNIIISLMGGLGLFLYGMNLMGEGLQKSAGTKLKKIIKLLTSNL
                     FMGVLVGTGVTAVIQSSSATTVMVVGFVNAGIMTLKQAIGVIMGANIGTTVTAQLVSF
                     DLTGMAPVALGVGIILYLFGNKPRIKNIAEILIGFGILFTGMDFMKMAVEPLRDYQGF
                     TDLLVTFGRYPLLGLLLGFGITAIIQSSSASMGMLVALAAEGLVPLSAALPILYGQNI
                     GTCVTSLLSSIGANKNARRAAMMHLIFNVLGTVIFLIFLNKPVVSMVTSWDPSNVARQ
                     IANTHTLFNIISVLILLPFTNLIIKLAIKLVPDRAGDIDEDETKTIKYIDDRMIETPS
                     IALANTIKEALRMGEKAKESLNASMEALVEHSTEKIDKTYRRERLINDLQKAILNYLL
                     KLSKAALDDDSREVVDTLFNTVNDIERIGDHAKNIAELSQVAIDSNIYFSEEGQSELD
                     VMYNRVVSAYTYALESMRSDNVDLACKVIKIEEQVDIMEKSCRANHMYRLNNNLCSIE
                     NGVIYLDVISNLERISDHAVNIAQQVIAKRLGND"
     gene            complement(4776..6380)
                     /locus_tag="KRH23_000314"
     CDS             complement(4776..6380)
                     /locus_tag="KRH23_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HHS5223613.1"
                     /translation="MLRVSNVKLGIDKDISLLKDVILKKLKIKEKNLVKYSIYKESID
                     ARKKGKMEFVYSVDVEVKDENKILNSKIKDVTKIKEIRYVNVPVGDKKLKNNPLVIGS
                     GPAGLFAGLLLAQMGYEPIILERGLDVDSRTKDISDFWTTRKLKNNSNVQFGEGGAGT
                     FSDGKLTTRIKDIRCRKVLEELVQFGAPDEILYSHKPHVGTDILKNVVKNIRNEIISL
                     GGQVRFNSKVTDIVVSNDSIQSVIINDTEKIDTDTIILAVGHSARDTYEMLYSRGIKI
                     VQKPFAIGARVEHPQDLINKAQYKDFYNHPRLGAADYRLIEHVSNGRTAYTFCMCPGG
                     SVIASASNDFEIVTNGMSEHARDKINANSAFLVNVTPEDFKSDNPLAGVHFQQKYEKL
                     AFELGGKNYNAPVQLVGDFINNKTSLNLGSVEPSYRPGYTLTNLSECLPSFVTETMRE
                     AFISLDKKLNGFAMYDAVLTGVETRSSSPIRIVRDENTLESVSIKNLYPCGEGAGYAG
                     GIVTAAVDGIKCAEKIIQKYTNNTKI"
     gene            complement(6428..6745)
                     /locus_tag="KRH23_000315"
     CDS             complement(6428..6745)
                     /locus_tag="KRH23_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5223614.1"
                     /translation="MDYIGIENITPYENTYEFSVYEYDDEITLGSEKLYVCELRVVLI
                     KVNSLYVERLHKSVEAMVLVKNLKKDLDKTLVVNKIKNFVLDEIWVENLVKENIEVIF
                     VES"
     gene            complement(6750..7115)
                     /locus_tag="KRH23_000316"
     CDS             complement(6750..7115)
                     /locus_tag="KRH23_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5223615.1"
                     /translation="MSLSLGNAIAVSTNFIKSNPAVPVYNGEEIYAVIYHIEIGYNNG
                     VSPDTKQYIIIDYKEFDLSMDKKNELINIAKEYCKSKGIVENENLEINLLDNEEAENF
                     LEKVFNNMKVIRGLITKKG"
     gene            complement(7196..8233)
                     /locus_tag="KRH23_000317"
     CDS             complement(7196..8233)
                     /locus_tag="KRH23_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SEC-C metal-binding domain-containing protein"
                     /protein_id="HHS5223616.1"
                     /translation="MLGRNELCPCGSGKKYKKCCLNKDIVSERACRKTELSQKQYTDL
                     YSKLYDYSRQDKFKEECEKAKEMFYIMQNDSVNEKFERFFNTYLIQDHIMENKKVMTV
                     GFLEENGANLSQSEVSILKSMFESYVSIYEVKEVSAGKIVLKDCLSGNELCTEDVKLL
                     RSFKIGSCMIARIVDIEGTNILIDITISISNEVKDIILKDIMNLFNQYQDVYKDMKSF
                     LIYHTHILYKYIQQLLDPSIAEYLKRERDKNDTKVNSENELAEEECKVLDTLKENVEK
                     ENIDACIEFWNEYKKNHENIKGAENGWAAAVEYYVKKEAGQPITQVQISKKYDISSST
                     LGKRYKDLKIS"
     gene            complement(8486..9070)
                     /locus_tag="KRH23_000318"
     CDS             complement(8486..9070)
                     /locus_tag="KRH23_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5223617.1"
                     /translation="MRLNNREKNLLKILLILVIILASDIAVSYLEENLTSLKNEKQNI
                     INKINNQDNYQIKDNKHIDDKYIESVELNKNEELKNNFNNSFLDKKTNKDIVLLVENE
                     LRDIVNVEYINQESSLDNHNKKQVNLEIKVNGELANVLKLEGVMKKLRLNNKLEKIEI
                     NKLKVNNFDAQNIPNEYKQEKDNIVECKMTVRVI"
     gene            complement(9085..9405)
                     /locus_tag="KRH23_000319"
     CDS             complement(9085..9405)
                     /locus_tag="KRH23_000319"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5223618.1"
                     /translation="MKSINELEDYISQNKLVDKSKNTLPTTDKTREKFSKIKLNEIKK
                     IYETIGINSITKISIDKNKLEMEGVCSDLDVLNNLRKIKYIKYYYIDSIVRDGEYYRF
                     RIKS"
     gene            complement(9529..10401)
                     /locus_tag="KRH23_000320"
     CDS             complement(9529..10401)
                     /locus_tag="KRH23_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pilus assembly protein PilM"
                     /protein_id="HHS5223619.1"
                     /translation="MAIIKKILNLEINDDYIRLVFLRKSHKKVFIDKSIIKEINFDIK
                     NDSNSIEKIKYIEDVVRFVKEEIGKSKILYKNLYFNIQIQDIVIRNVEVLNTKKKRDI
                     LSMIEFEITQYIPININNYSIKYKVINSKNDKLNIQVILFPKSIIQLIKNISENLNMN
                     PKTININFDILQKLINLNLIENFSEEGVFIECKKSQLIINITKDKKIRETYLLSKEGK
                     SYEFIKRLLRDFKYVYYYGIENCFIEEYFKYTDKSIEVNPLRLKDKVKVENNFDADLE
                     DNRINYISNIGMII"
     gene            complement(10454..10813)
                     /locus_tag="KRH23_000321"
     CDS             complement(10454..10813)
                     /locus_tag="KRH23_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0015627 - type II protein secretion
                     system complex [Evidence IEA];
                     GO_process: GO:0015628 - protein secretion by the type II
                     secretion system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HHS5223620.1"
                     /translation="MINLINKKRKGFTLVEMIVVVTILGVISSIALVKYSKVQESAKL
                     NADYTNAANIVTAASMAINDDEKTIDSLSVETLKEKGYLNTVPVPQSTSGKFELVIND
                     SGTDISVNINSKQFYPK"
     gene            complement(10867..11952)
                     /locus_tag="KRH23_000322"
     CDS             complement(10867..11952)
                     /locus_tag="KRH23_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0015628 - protein secretion by the type II
                     secretion system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HHS5223621.1"
                     /translation="MRLSKNIFYNLEKFYLVLNRISDKEIRVICKEIGILLESGCEIT
                     KIFEIIESQSSKKVKNLLSIVSNHIQKGNSIAESFQITGIFSKFFISMIKAGETSGNL
                     DIIMSDLSNYYDKEYKLKMKIITISIYPIILIILSILSMLFIFVFVIPNFQVVFTNNG
                     IEPPLITRVLMGISTVVTNNLAYIIFSFILFSIGSIYFFITNDNIKKFINSLKFKIPF
                     IKKINQLVATTRFSRALSVLISSGIQIVEAIDMSASVIDNEFIYERLKISNNYIKKGN
                     SIGKSLNLANVFPKLFISMANTGEESGKLDKSLNVINKFYENELNNKIEQIMKFIEPM
                     LIVFMGLIIGTFILAMVVPMFDAITNF"
     gene            complement(12123..13466)
                     /locus_tag="KRH23_000323"
     CDS             complement(12123..13466)
                     /locus_tag="KRH23_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GspE/PulE family protein"
                     /protein_id="HHS5223622.1"
                     /translation="MLIPEKLAKKYNVFPVEFQDDNLVVEIEDEDIYALQDLRLATGK
                     EIILKKEKKELISEKIEKYYNSFELDEDYAKKLFENLLEKAIKENASDIHIEPFKEHL
                     IVRMRVDGELKEVSKFLVDVYPSLSTVIKLKASMDITEKRLPQDGRVDIKLGGNLIDI
                     RVSSIPTVYGEKIVLRILNRDTFLKDKLELGFSEEAIKSINRIINKRAGILLVTGPTG
                     SGKTTTVYSLLNDLKGINKNIMTIENPVEYKMDGISQIQVNSKVGLSFDVGLRAILRQ
                     DPDIIMVGEIRDAETAKIAVRAAITGHLVISTLHTNDAVSSIARLLEMQIPPYLLNAS
                     LIGVISQKLVRKVCNHCSHEIMIKDNFSGDVNTKVAVGCEKCNDKGYFGRTAIYEILE
                     INDDIKTCIRNMEDSSTIKDVAQNNGMITFEDSCKRLINEKITTLEECLVVNEMI"
     gene            complement(13495..14175)
                     /locus_tag="KRH23_000324"
     CDS             complement(13495..14175)
                     /locus_tag="KRH23_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DUF881 domain-containing protein"
                     /protein_id="HHS5223623.1"
                     /translation="MKKQYVFIILASTILGILVGTIFRDYSNEETVYTSKDKSIRKEI
                     KMTRKSIKELTKEKDKLDKEINSMKQNQKNSEEISEIETLRDSLSYSDVKGSGIILSI
                     DAIDEKTGNIANSIDYNKILVKVINELKVNGGKYIEINGQRINQYSEVVLAGSHININ
                     GVPVAQPYEIKCIGDKEKLSNYVDKGSKYLDSIQTNYPMKISIKTEENISMKKMNIPN
                     KLKYIKGD"
     gene            complement(14567..15646)
                     /locus_tag="KRH23_000325"
     CDS             complement(14567..15646)
                     /locus_tag="KRH23_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HHS5223624.1"
                     /translation="MEGKVKKAFPGGNTSQGSYSFFDYIIPENVKRVFCLKGGPGVGK
                     SSLMKKIYKEFLHRGYDIDLYHCPSDPSSLDGLVIKKLGVVLMDATAPHTMDPKLPGA
                     LDEIINLGDYWNTEELEKNKQEISVYDKDISNSFKRAFKFLKSAEPIFRDIEEKYSDC
                     MDYGKVNLVTEEFIKRLFDGVKSTGNLKREKHLFGSAITPVGCLDYTENILKDVKKVY
                     YLDGEIGTGKTTLLNKVYKKAIEKGLNVEVYHYPLIPEKIETVLLTDLDIGITISTTF
                     KEEDTIDLNQFLNREKLLKYEEDIKFDEKVLDDLICWAVLNLKRAKSKHDIIESYYSP
                     NMRFDEVGKLRDKLIKRILKYEENL"
     regulatory      15934..16049
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            16224..17594
                     /locus_tag="KRH23_000326"
     CDS             16224..17594
                     /locus_tag="KRH23_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HHS5223625.1"
                     /translation="MKQKWIVLIIICIGVFMSTLDGSILNIANPTIAADFKINMSQIQ
                     WVVTAYMLVVTATMLFFGKLGDKVGSNRLYTLGFFIFTIGSFMCSMSNNLSTLISSRI
                     FQAVGASILMATGLGIVSNAFPANEKGKAIGITGAVVGIGNMSGPVIGGIILEHFGWP
                     SIFIINIPIGIIAVFLGIKFLPKPVLDEQNKSFDIPGLLLFASCTTLILLAMNEKGNT
                     RLYLGITALIIFLLLALREVKFEQSFIDLPLFKNRNFTVGNIIGVACYFPQMAVSFLL
                     PFYLEQLKNLSPMMAGYVMTVHPLIMVLIAPIAGSLSDKHGAKNILTASFSFMTISLV
                     GMALLKADSPLYLLIVCLVIFGLGLGAFSSPNNSSILADVPPQKQGYGGSFLATIRNL
                     SFALGTAFFSSFFAQSLTYNQKFKSHTSAYVIASNQSYWIAASVCFIGLILTVFFMRK
                     TDKSIS"
     gene            complement(17859..18470)
                     /gene="yihA"
                     /locus_tag="KRH23_000327"
     CDS             complement(17859..18470)
                     /gene="yihA"
                     /locus_tag="KRH23_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTP-binding protein
                     YihA/YsxC"
                     /protein_id="HHS5223626.1"
                     /translation="MKIRSSEITMSAVNKSQYPAEGIPEIALAGRSNVGKSSIINTLL
                     NRRNFARTSQTPGKTRTINFYLINNEFYFVDLPGYGYAKIAKSEKEKWGGIMERYLES
                     RQELCSIFLLVDIRHEPTADDKLMYEWIKHFGYNCVVIATKADKISRGQYQKHISIIR
                     KKLQMESSEKVIPVSSLKKTGVEELWEEIVNQYNQHGYEITVD"
     gene            complement(18460..20823)
                     /gene="lon"
                     /locus_tag="KRH23_000328"
     CDS             complement(18460..20823)
                     /gene="lon"
                     /locus_tag="KRH23_000328"
                     /EC_number="3.4.21.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase La"
                     /protein_id="HHS5223627.1"
                     /translation="MEQNYTKIDHELPLIPLRGLAIFPYMILNFDIGREISLKALDQA
                     MMDEELIFLTSQKEAEVDEPGEEDFYHVGTICKVKQMIKLPGDTVRVLVEGVSRGRVK
                     KIEQEDGYFRAVIEEIVFDSDNLDSETEVEIEAFVRNVFDAFEEYINIGNRVSPEILI
                     SLADIEDVDRFIDTIAANIYLKSSQKQEILEEFDIRKRLELIYSILLEEIDILKIEKK
                     ITLRVKKQMNKVQKEYYLREQLKAIQKELGEEEDINSEADEYREKLKKIKAPKTTKEK
                     IEKEIDKFSKISSMSPDVSVSRNYLDTIFSLPWNKETKDKLDITKAKDILDEDHYGLE
                     KVKERILEYLAIRTLAKSLKGPIICLVGPPGTGKTSIVKSIARALNRKFVRISLGGVR
                     DEAEIRGHRRTYVGSIPGRIINGVKEAQTKNPVFLFDEIDKMAADYKGDPASAMLEVL
                     DPEQNKDFVDHYLEIPFDLSKILFVTTANSLGNIPRPLLDRMEVIEVSGYIEEEKLNI
                     AKKYLLPKQIKEHALKENFIKIDDETLRSIINHYTREAGVRTLERTIGKICRKVAKKY
                     VEDPTLEEVVINKSDLETYLGKDMFKYQLAEVNPQIGLVNGLAWTEVGGVTLEVEVNV
                     LKGKGEIVLTGKLGDVMKESAKTGISYIRSIVDKFDIDPEFYKTNDIHIHIPEGAVPK
                     DGPSAGITMALAVISALTKRPVPGNIAMTGEITLRGRVLAVGGVKEKLLAAHRAGITK
                     VLIPKECEADLDEIPENVKEKMEFVLVEHMDEVLEQALLKSGENNEN"
     gene            21003..21515
                     /locus_tag="KRH23_000329"
     CDS             21003..21515
                     /locus_tag="KRH23_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015109 - chromate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015703 - chromate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromate transporter"
                     /protein_id="HHS5223628.1"
                     /translation="MLKLFLTFLKIGAFTFGGGYAMVPLIQDELVNKQKLLEQEEFID
                     YLSIAQSYPGVLAVNISVLLGYKLYGIPGVLICTLGSALPSFCIVLVLSYLYFKNSSS
                     KILDGFFKGVAPVVIALILYSFTSMFKKLPKSKTNILLLIIAVLSVGVFNISPIYLII
                     GGGVYSLCQK"
     gene            21503..22030
                     /locus_tag="KRH23_000330"
     CDS             21503..22030
                     /locus_tag="KRH23_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015109 - chromate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015703 - chromate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromate transporter"
                     /protein_id="HHS5223629.1"
                     /translation="MSEIILLFLIFLKIGAFSFGGGYAMLPFIQQEFISKYHFITNQE
                     FLDLLAISQSTPGPVAINSATFVGFKTAGFFGSLAATIGVTIFALIGLTIISKLFSKF
                     KNNKKVENLLTVLRPITLGFILSAAFSSAKEVNWDLYGIIAFIASFYLLYKGKIGSIA
                     IVFVFGILGILLTFL"
     gene            complement(22101..23351)
                     /gene="clpX"
                     /locus_tag="KRH23_000331"
     CDS             complement(22101..23351)
                     /gene="clpX"
                     /locus_tag="KRH23_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HHS5223630.1"
                     /translation="MSKYEEKRQLKCSFCGKNQDQVRRLIAGPNVYICDECVELCDEI
                     IQEEIEDTIDEDTTSLPKPKEMMEILNDYVIGQEKAKKALSVAVYNHYKRIYSKKSSS
                     KDIEIQKSNILLLGPTGSGKTLLAQTLARTLNVPFAMADATSLTEAGYVGEDVENILL
                     KLIQAADFDIEKAERGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKILEGTVAN
                     VPPQGGRKHPHQEFLKIDTTNVLFILGGAFDGLEKIIQKRGGDKTLGFGAKIESKKEL
                     DLGKLYEKVLPEDLLKYGIIPEFIGRIPVLATLELLDEDALMQILQEPKNALVKQYKK
                     LLELDDVELEFEEGALRAIAKKAIERNTGARGLRSIVESVMMETMFEVPSRDNIKKVI
                     VTEKSVNEDSVNPIIVLKDQEESA"
     gene            complement(23370..23954)
                     /gene="clpP"
                     /locus_tag="KRH23_000332"
     CDS             complement(23370..23954)
                     /gene="clpP"
                     /locus_tag="KRH23_000332"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009368 - endopeptidase Clp complex
                     [Evidence IEA];
                     GO_function: GO:0004176 - ATP-dependent peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HHS5223631.1"
                     /translation="MALVPVVVEQTGRGERSYDIFSRLLKDRIIFLGDQVNDATAGLI
                     VAQLLFLEAEDPDKDIHLYINSPGGSITSGMAIYDTMQYIKPDVSTICIGMAASMGAF
                     LLAAGAKGKRLALPNSEIMIHQPLGGAQGQATDIEIHAKRILKIKETLNEILSERTGQ
                     PLEKIKMDTERDNFMSALEAKEYGLIDEVFTKRP"
     gene            complement(24104..25390)
                     /gene="tig"
                     /locus_tag="KRH23_000333"
     CDS             complement(24104..25390)
                     /gene="tig"
                     /locus_tag="KRH23_000333"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005854 - nascent polypeptide-associated
                     complex [Evidence IEA];
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA];
                     GO_process: GO:0051083 - 'de novo' cotranslational protein
                     folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HHS5223632.1"
                     /translation="MKAELIKKEGNKVTLKITVDNNKFEAAVNKAYNKSRNKYNIPGF
                     RKGKAPRIVIETQYGKGIFYNDAIEILFPEVYPEAIKELDIDPIDNPDLDIEEISKDN
                     GLVMVLNVEVKPEFELGNYKGIEIAKVENTVSDENVDAKLQEMVEKNARLVSVEDKAL
                     EDGDTAIIDFEGFENGVAFDGGKGENYNLVIGSNTFIPGFEEQLVGKKAGEEVEVNVT
                     FPEEYHSQDLAGKPVVFNVKINDVKVKELSALDDEFAKDTSEFDSLDELKADVRAKLE
                     EEAKNRADAETRNSVVEKVAENTEIEIPEVMIQHQIDNMLNELNYQLQYQGFGLQQLL
                     EMTGRTMEELREERKEDAKKLVKSSLVLEAITKAEGIEATEEEFKAELEKMASAYNME
                     VEKIEASLRDADKEDIKGQIKIRKTIDLLVDNATIA"
     gene            complement(25584..26054)
                     /locus_tag="KRH23_000334"
     CDS             complement(25584..26054)
                     /locus_tag="KRH23_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HHS5223633.1"
                     /translation="MKIGIVSDTHMMIKNMEKTIPYLKECDLIIHAGDNFTDSRYIHS
                     MTNVGIIAVKGNCDFDAVEEEVVFEVANKTIFLCHGDKYGVKYGTNMLEKKATEVDAD
                     IVIFGHTHTPFREIKDGVLYINPGSTSLPRGVSYKSFVIMDIEEDDIKIEEIRI"
     gene            complement(26054..27403)
                     /gene="rph"
                     /locus_tag="KRH23_000335"
     CDS             complement(26054..27403)
                     /gene="rph"
                     /locus_tag="KRH23_000335"
                     /EC_number="2.7.7.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0009022 - tRNA nucleotidyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HHS5223634.1"
                     /translation="MTRSYDRSNEQIRPVKITRDYTKYAEGSVLIEMGETKVICTASV
                     EEKVPPFLRNSGTGWINAEYSMLPRATQQRKIRDASRGKIDGRTQEIQRLIGRAIRSV
                     VDLNKLGERTIWVDCDVIQADGGTRTASITGAFVAVAEAIYKLYKAKTIKEMPITNFV
                     SAISVGIVNGIHMLDLCYEEDSKAQVDMNIIMTDKCEFVEVQGTGEEKPFSRADLNLL
                     LELGEKGNKELIRLQREALGEISDEILGMDYGNEVVIATNNVHKLEEIGEILKDFEYK
                     VYSLKDVDLAGIEIVEDGKTFEHNALIKARTIAKKTKLIAISDDSGLEVDALGKKPGV
                     YSARYAGEHATDEENRKKLLKAMQNVPMSKRNARFVSAIAVVFPDGKEFVVRGICEGM
                     IGFEEKGKNGFGYDSLFIVKGYDKTFGEIPSVIKNSISHRANALKLMKQEFIKRVVK"
     gene            complement(27563..29587)
                     /gene="ligA"
                     /locus_tag="KRH23_000336"
     CDS             complement(27563..29587)
                     /gene="ligA"
                     /locus_tag="KRH23_000336"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003911 - DNA ligase (NAD+) activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HHS5223635.1"
                     /translation="MSVKDEINKLIETINYHNERYYNQDSPEISDYEYDKLMKELISL
                     EEEHPELKRIDSPTNRVGGKPLDKFNQIVHKTPMLSLSNAFSEQDLRDFDKRVQEYVG
                     ENVEYVVEFKIDGLSVGLTYNNGEFEKGATRGDGVVGEDISQNLMTVKSIPLKINDKK
                     ELIVRGEVYISKDNFRKVNEQQEEQEQPLFANPRNLAAGSLRQLDPKLTAKRPLDIFV
                     FNMENIEEYDLESHSESLEYLEKLGFSVSQSYKVCKSIDEVIEHIEYWTDNRGNLDYE
                     IDGMVIKVNNIKQRDEMGYTAKSPRWAIAYKFPAEKKKTKIVDIIVEVGRTGTITPSA
                     ILEPVRLAGTTVSRATLHNEDYIREKDIKINDTVLVQKAGDIIPQVLEVIKEERTGDE
                     IDFKMPEKCPVCSEPTIRLEGEAAVKCINMSCPAQIRRGIIHFVSRDAMNIDGLGESI
                     ITLLLNEKIIQDVSDLYYIKKEDVVDLERMGEKSADNLINSIEKSKENDLWRLINGLG
                     IKFIGVKAAKILAYNFKDLDEVISATSEQLEELEEFGSIMANSVVEFFKEDKNMNVIN
                     KLKNVGVNTKSLDNTGEKVEKIFEGMKIVLTGTLPTLKRNDAKDMIEKRGGKATSSVS
                     KSTTFVLAGEEAGSKLTKANDLGIKVIDEERFLELLKLSSKDEVKAVLES"
     gene            complement(29773..30711)
                     /locus_tag="KRH23_000337"
     CDS             complement(29773..30711)
                     /locus_tag="KRH23_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="HHS5223636.1"
                     /translation="MKVLFTINYGKEKFDKIRELGYDVIHYSEDSIENNEDVNTADVL
                     VTYNPFERLDISKMKNLQYIQTTSVGIDQLPKEEVLKRNIKIANNRGGYSVPIGESIV
                     LYILEIYKNSAKFFKQQQNKEWKMDFSVSELYGQRVGFLGTGTISSEAAKRLKAFGVE
                     IWGVNTDGSSKKYFDKCFATEDMNIVFEECDIVVVAMPSTKSTDGIVNKDMFKLMKDG
                     SVFINVGRGNTVNQKDLEECVEKFRGVALDVFESEPLNKDNKLWECENVIVTPHNSWV
                     SDKNKERTFNMVYNNLKHYIMENKPVDNVVDISRGY"
     gene            complement(30813..31235)
                     /locus_tag="KRH23_000338"
     CDS             complement(30813..31235)
                     /locus_tag="KRH23_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3783 domain-containing protein"
                     /protein_id="HHS5223637.1"
                     /translation="MSFEKINNNNLDKIHNRKCIMLVNFNKKELSLIKNVSNFAGIRD
                     HIILSDKNGENIIRDILDGNISNECENGIKSKSVIFNNTPSTQVNTFLEGLKKVRINR
                     PFTAMVTETSIDWTLNNLIENLVQERNAMSLGKTIEHK"
     gene            31423..32706
                     /locus_tag="KRH23_000339"
     CDS             31423..32706
                     /locus_tag="KRH23_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugated bile salt MFS transporter"
                     /protein_id="HHS5223638.1"
                     /translation="MNTLLNNKFSIKNFSNAWVIVLGCMLIQAVPFSIVASIQPQFIS
                     YVVEGEGFSLASFSLIFTIGTIASAIASPFIGVLFSKVNIKILYLLGCIISSIAFATF
                     SICTELWQFYTVSCIVQIGATIISAIGIPVLISAWFDEESKGKALGFAFAGGSIGSIF
                     LQPLAVRLLATQGYSRSYLIFGIIALIVGIPVILFILRMPKDINEKVKSKGKKEKASD
                     TISPSVWGYTLKEAKKIKYFWIMTIGFIFVGIYVSSLSVQYPTYLRNYLNPILIGTVG
                     STFALFALIGNLFGGLLFDKFGQTKPLIISFVLVLIATLSLLLVDKSSTFAFVFAILK
                     GLSVFAYMIGPAYLTGSFFGQKEFGSIYGIVQLIFAVGFALGSTLFGLLVDNFGYRFS
                     WSIIILSVIIAYTLLIITSIGMKKLNKERLDKLMQ"
     gene            complement(32784..33299)
                     /locus_tag="KRH23_000340"
     CDS             complement(32784..33299)
                     /locus_tag="KRH23_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0009061 - anaerobic respiration [Evidence
                     IEA];
                     GO_process: GO:0019645 - anaerobic electron transport
                     chain [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HHS5223639.1"
                     /translation="MNYFVIADPDKCIGCRTCMIGCVVAHSDEDIFYQNPDEINFNPK
                     LSVIKTKEVSAPIQCRHCEDAPCAKACPNGGIVRVGNTIKINEENCIGCKTCMLACPI
                     GAIDIVTLKDVDEGKLCFRERMTANKCDFCIESPEGPACVNVCPTKAFTIVKDEDIDS
                     KVKNKRKLAIL"
     gene            complement(33299..34675)
                     /locus_tag="KRH23_000341"
     CDS             complement(33299..34675)
                     /locus_tag="KRH23_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0016695 - oxidoreductase activity, acting
                     on hydrogen as donor [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="[FeFe] hydrogenase, group A"
                     /protein_id="HHS5223640.1"
                     /translation="MIINIDKDLCTGCRECSKVCPVNAIEGEEGKPQEINLDRCVMCG
                     QCVQTCKSYASVIDEGFEFLQEKKQEREIPESINEPIFAAYNVCDIDKVKKALSDPNV
                     FTMVQCAPAVRVALGEDFGYYLGYLGAGKMAAALRALNFDRVYDTNFAADLTIMEEGS
                     ELIKRVTEGGTLPMFTSCCPAWVKFMEKNYPKLTNHLSSCKSPQQMGGAIFKTYGAEI
                     NNVDASKIFSVSIMPCTCKKYECDREEMDSSGYRDVDVVLTTRELAYLIKDMGIDFKN
                     LREEKFDSPLGSYSGAGTIFGVTGGVMEAAIRTGYELITGESIPDVEVKQVRGENGFR
                     KSTIKIGDLDLRVGVVSGLKNVIPVLEDLEKGKLDVDFIEVMTCPVGCVSGGGQPKIL
                     LEEYKELAYENRTKATYVHDEHLAIRKSHENPDIKKLYDEYLVEPLGEKSHHLLHTTY
                     CIGKEVAK"
     gene            complement(34700..35251)
                     /locus_tag="KRH23_000342"
     CDS             complement(34700..35251)
                     /locus_tag="KRH23_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0009061 - anaerobic respiration [Evidence
                     IEA];
                     GO_process: GO:0019645 - anaerobic electron transport
                     chain [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HHS5223641.1"
                     /translation="MKNKIGSFVIADPNKCTGCRACEVACFTMHNQHNNVGYTVGTVD
                     IPVIPRLYLVKGDNFCMPIQCRHCEDAPCLNSCPQKAIVKENNIMSVNEEKCIGCKTC
                     LLACPFGAIDLLPQYEDGKEVEQVILDENKKIAYKCDLCKDNEKIACISACPQEALKL
                     VTPIDDKKAKNRQAALSLLLTNK"
     gene            complement(35309..35524)
                     /locus_tag="KRH23_000343"
     CDS             complement(35309..35524)
                     /locus_tag="KRH23_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5223642.1"
                     /translation="MQIHRELSKSENEYMCTKKEEQRYSKCEICGVLIDDTDKVYNNT
                     YNLCKKCKRNISTEKIVKYINIYDESK"
     gene            complement(35493..36326)
                     /gene="fdhD"
                     /locus_tag="KRH23_000344"
     CDS             complement(35493..36326)
                     /gene="fdhD"
                     /locus_tag="KRH23_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009326 - formate dehydrogenase complex
                     [Evidence IEA];
                     GO_function: GO:0016783 - sulfurtransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009061 - anaerobic respiration [Evidence
                     IEA];
                     GO_process: GO:0015942 - formate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate dehydrogenase accessory
                     sulfurtransferase FdhD"
                     /protein_id="HHS5223643.1"
                     /translation="MNNIYSKTKLQENSKDKVFENSYSLVDYKYLNSFNVEVSKINEH
                     EVSIDNEEIVAEYPLSFILNDKYVNTFLCTPYNLEELIVGFLKTKGYIENKKSLLKFE
                     INESERFAKVTIQEKQKNQDEQIIFLNSLDYITCAPVKSNIKINYDTIYSIMDKNLNS
                     SELFKNTGGVHSVSVFNFDKKIVTCEDVARHNAMDKAIGFCVLNDITLKDKIVAVSGR
                     ISLEMILKVAMTQIPIVVSKSAPTNLSIELSKKLNITLIGFVRGRRMNIYANPQRVIK
                     K"
     gene            complement(36375..38519)
                     /gene="fdhF"
                     /locus_tag="KRH23_000345"
     CDS             complement(36375..38519)
                     /gene="fdhF"
                     /locus_tag="KRH23_000345"
                     /EC_number="1.17.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009326 - formate dehydrogenase complex
                     [Evidence IEA];
                     GO_function: GO:0008863 - formate dehydrogenase (NAD+)
                     activity [Evidence IEA];
                     GO_process: GO:0015942 - formate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_except=(pos:complement(38103..38105),aa:Sec)
                     /transl_table=11
                     /product="formate dehydrogenase subunit alpha"
                     /protein_id="HHS5223644.1"
                     /translation="MEKKILTVCPYCGAGCQLYLVVKDNKILRAEPANGRTNQESLCL
                     KGRYGWDFLNDPKILTPRLKKPMIRKQGVLEEVEWDEAINYTASRLNEIKEKYGPDSI
                     MGTGSARGPGNEANYIMQKFMRATIGTNNVDHCARVUHAPSVAGLAYSLGSGAMSNSI
                     PEIENADVLFIFGYNGADSHPIVANRIVKAKKNGAKLIVTDPRVTESARIADIHLPIK
                     GGTNMVLVNAFGNVLIEEGLYNKEFVQNHTQGFDEYKEIVKPYTAKYAEKITGIPEEL
                     IRKAMREYAKGKKAMILYGMGVCQFGQAVDVVKGLASIALLTGNFGRESVGIGPVRGQ
                     NNVQGACDMGALPNVYPGYQNVTDDKIREKFEKAWGVRLSPNNGYSLTQVPNLVLKEK
                     KLKAYYIFGEDPVQSDPDASEVREALDELEFVIVQDIFMNKTALHADVILPATSWGEH
                     EGVYTCADRGFQLMRKAIEPQGDVKPDWQIISEISTAMGYPMNYKNTKEIWDELRQLC
                     PSFLGATYEKIETQGCVQWPCKSESMEDKGTMYLYEGQKFSTPNGKGNLFAAEWRPPM
                     EVEDDEYPFSLCTVREVGHYSVRTMTGNCRTLSSLEDEPGRVQINSNDAEKLGIEDDE
                     LVRISSRRGSVITRATVTDRVKEGATYMTYQWWVGACNELTIANLDPISKTPEYKYCA
                     VKLEKLEDQELAEKCVREEYQSLKDKMTATNI"
     gene            complement(38770..39828)
                     /locus_tag="KRH23_000346"
     CDS             complement(38770..39828)
                     /locus_tag="KRH23_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lysylphosphatidylglycerol synthase transmembrane
                     domain-containing protein"
                     /protein_id="HHS5223645.1"
                     /translation="MDRLKNIRKSLLQYTFLFLLIGITIYLVFKTLDIKMLSNVMVMV
                     DKKFLFIGALAIMCHIMLEGVVMKIIIESTHKVNIRFIGFKLAIMGFYYNLITPFASG
                     SQPVQIYVLKKCKMPLSKASAVVTNKSIIFQIVVTFYCTILVLMNFAMLEKQMKMIMP
                     LVFLGIAINSFVLIMIILVILNPKKIKYFMRITIKHLSKIKFLKFLDNKIESIESFID
                     DYSKAINFFAKNKKVLISTIIVTFIQLSAYFSVSFWIYKAFNLQGYSYIYILTLQAFL
                     YMAISPIPTPGNVGANELAFFTIFKSVFPQPLMGYAVFLYGGFMYYLILIGSGIFTVI
                     THYRMKNRIGRNIVLSEN"
     gene            complement(40039..40698)
                     /gene="cprR"
                     /locus_tag="KRH23_000347"
     CDS             complement(40039..40698)
                     /gene="cprR"
                     /locus_tag="KRH23_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CprR"
                     /protein_id="HHS5223646.1"
                     /translation="MSKILVVDDELDMLKLIENVLKRDGHEVKVISDVEKAMNMDFNY
                     FNLIILDVMMPKMDGFEVCKTIRNKVDCPILFLTAKNMESDIMYGLGIGADDYITKPF
                     GVGELRARITAHLRRESREKKNLLTISNVQFNFLGKEVSIDGKKINFTKSEYLICEFL
                     AKNKGQVFSKERIYESVYGFDGESDISTITEHIKNIRSKLKQYDIYTIETVWGIGYKW
                     V"
     gene            41009..41638
                     /locus_tag="KRH23_000348"
     CDS             41009..41638
                     /locus_tag="KRH23_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3786 domain-containing protein"
                     /protein_id="HHS5223647.1"
                     /translation="MDEKITKNNYNVPFDYVRKKLKELDPHTISNLSNIPFNNGLNRF
                     TLNFFDRQYIIDYPSGEVWNSNGSLCNNFELKILIVRYLINAKGIPRTNKYVTFKEIP
                     GGNVYYPNFLNRTLSRLSEVFTSQIDKYKLVMEKIGAEKVNMGDLAYRFTYMGNTSMV
                     FILWFGDDEFPPNSNILFDSNIVYYFNAEDLAVVPDTAINAILNKINQL"
     gene            41862..42539
                     /locus_tag="KRH23_000349"
     CDS             41862..42539
                     /locus_tag="KRH23_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prenyltransferase"
                     /protein_id="HHS5223648.1"
                     /translation="MNPDDTLLKECADLIFSTWREDGRFKLHPNGGIYPCHTANAANV
                     LCHMGYASDIRMQKTFQHFLDTQYTDGGWRCNKFSFGRGPETEYSNPLPTLNILNAFR
                     FSNYLNKESKLDKAVDFLLDHWTIKKPIGPCHYGIGTLFMQVEYPFRNYNLFLYVYVL
                     SFYNRAKKDNRFLEALKILESKMIGNKIVVERVVPKLSKLSFCKKGESSEIATTHYYE
                     ILKNLEK"
     gene            complement(42635..43423)
                     /locus_tag="KRH23_000350"
     CDS             complement(42635..43423)
                     /locus_tag="KRH23_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5223649.1"
                     /translation="MCILELIKFELKKIELKHVLIFVIISILCIFITGILDYNELIFY
                     NDVPIMDTYSIAGWLGIIKISDVFIPIMSAITIIYVFSKDYSGNINEILTLYNKKKYN
                     QFIVFRWCVILAIYTVLLLISITIVYTFTSVKGFNIDKIDFVYSVKPIDVFLKTFPTL
                     LWYTTFPLMILTLTKNRFTTIAILITYTFADIFFILHMYPFVSMINVNGFYIQKMFYM
                     PNNIDVRFNELKNYFFINRGSLVVISIIIVFYIARKSTVLKKSK"
     gene            complement(43424..44296)
                     /locus_tag="KRH23_000351"
     CDS             complement(43424..44296)
                     /locus_tag="KRH23_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HHS5223650.1"
                     /translation="MINKLEIRNLNFNYKNKKALDNINLTLTDGVVALLGPNGAGKST
                     LMRLLVTLYETSIGEIELNNIKYSKNNEKIKANVGYVPQDFDMYNNINGQEYLEFVAK
                     MRGVSKNDLKKHIQKVVSKVNLDKFINKKIGTYSGGVKRRLGIAQALIGDSKLIVMDE
                     PTVGLDPEQRNEFRRLLPEISKNSIVLISTHIVEDIQFNCDKLIILNQGKILYDGTIN
                     KFIDMVEVYSVVVSNDEFEYLERNIDIIDYRRVKDGVQVKYIGKNTEKLKDSLRIDTT
                     LQDAYINFLHKELK"
     gene            complement(44311..46020)
                     /locus_tag="KRH23_000352"
     CDS             complement(44311..46020)
                     /locus_tag="KRH23_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5223651.1"
                     /translation="MSSIKVISDFITKIIRKNILFAITVIIINYHLIQRWTHISNRGI
                     SFNDYLSLSVYTCMTISILTMLNVIFYMRKSYDTVKILCRNNFDYFLGISVAVTRNNF
                     IFCCIPIIYAIAYSSLIRTLSIVTIKSTIFILIFEWFLPLTILSIVISFISVIINNLI
                     LKITLSSVFLYLTSTKMLDRVIDIKEPFFKALFKSLNIFEDQSYAYYSDFVGKVNNSA
                     YVIDKIIPTLFAITLIIVAYLILNDIRKKQIKSLIVIVVYSILFIGLNYISIDMSTYR
                     DEERSYGEYLKKSNISDIKIKSHDMKIDFKSKSNIKDRIVLLNTSNEELTNINMILDE
                     IFDIKYIKVNSENIKFNKKKDLIEVNLKESLEPNDEVTLDIEYEGYINVLTSWNQNKY
                     IATKDDIMLPPGSLAWYPKVNQSSCMAYKINLSSKNNVYSNLPLLNKTSNFLKKDYIF
                     EGKSNDIAIYAGEFKEEVKDDIKIIYPSDSNVNMDIEEKIKFLIETRNEILGDSKASV
                     DAKKYVDEVDNVMESIKRKKINMILVADLPSNEFLYEDSKGEKISITIYHWLSGNILI
                     IDK"
     gene            complement(46167..46748)
                     /locus_tag="KRH23_000353"
     CDS             complement(46167..46748)
                     /locus_tag="KRH23_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator ArgB-like protein"
                     /protein_id="HHS5223652.1"
                     /translation="MFKRLSYKFANILVNNEIVESEDFEIYRYGFETLIYFIVNILVA
                     LFIGIIFDRFIHTIIFLSCYCTLRQFTGGYHARNYKECTLTFAVIYLITIFSANNIDI
                     NKYKYLLVLLMIISILTIYKLAPLEHRNKPLSESEKKHYRKTVQKILFVIICLIILCK
                     ILNIFQQYVIYAIISIYWIAILIYIGMKVNSDQ"
     gene            complement(46807..46947)
                     /locus_tag="KRH23_000354"
     CDS             complement(46807..46947)
                     /locus_tag="KRH23_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic lactone autoinducer peptide"
                     /protein_id="HHS5223653.1"
                     /translation="MKKIALNLLKNISALSFGIAVLSANSASSWVAHQAKEPQALQKL
                     KK"
     gene            complement(46959..48275)
                     /locus_tag="KRH23_000355"
     CDS             complement(46959..48275)
                     /locus_tag="KRH23_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HHS5223654.1"
                     /translation="MLTNLSVGFWNIINLVSGTIDWIIFFLVIHLVGKRKISNIRYIF
                     TTIIIIIFMAYINVVKVFPNIKILLCMVIGISFYITSYEDKIYKSIIVSLLFWLGLMV
                     AEGSAVGLVVFINKLNNINITQHENLFRIQAIIMSKVFLFIGFILFKYFKLSLDFKPK
                     DMILIGIPILSNIVSLLLIFEYNLRVNTITTENLFIFIFAILLILSSSIILLIVIGKI
                     VQDDKLNLEYELINERIKTNYRNYENINEVHDRLKYVYHDLKNHMICIKNYDTKEEII
                     SYINNLEFQISEFEHFKNTGNKTLDLILAEKISICKKYDIQIEDNINISKLNFIKNND
                     ICSIFANSLDNAIEACMDINNEIEKRIEVKATYINKFAIIKFINTKVNDIKLIDKRIQ
                     TSKDDDKIHGIGLASIKYIVNKYGGETIVNYSDNEFILKIMIPIKS"
     gene            complement(48269..48979)
                     /locus_tag="KRH23_000356"
     CDS             complement(48269..48979)
                     /locus_tag="KRH23_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytR/AlgR family response regulator
                     transcription factor"
                     /protein_id="HHS5223655.1"
                     /translation="MINIGICDDELHYRIKIKDILSEILSSYPINYNIYEFSAGEELL
                     NNYPKDLDILIMDIQMKTINGMDTARKIREFDHKLEIIFVTSFVEFMQEGYEVKAYRY
                     ILKPINKEKISKSVLPCINEMMKKRNNYLTINVKNYVDRIKIDSITYIETDRPNILIY
                     THDDMYITKMSISKIEKILNEYGFFRCHNSYIVNLKLVESMSGSTVIVDGKSIPISKY
                     RVKGLKLAITNILGDIVC"
     gene            complement(49418..49993)
                     /locus_tag="KRH23_000357"
     CDS             complement(49418..49993)
                     /locus_tag="KRH23_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1062 domain-containing protein"
                     /protein_id="HHS5223656.1"
                     /translation="MKKITWEVEYISQLPVIRYCKKCGKKTEYICSGLFRVNAQHKYL
                     DIWLIYKCSNCDSTWNSTIYSRVNPKSLNPEILEQFHTNDYNLVKQYAMNMELLHRNG
                     AEVGIPEYKIVGQEININDFTQVHIISKYPCQLKVSTLLREKLGLSRKVFDEMLDCGI
                     IRSNSGVDLKKGKLNYEIMLDIGKEKQKSSN"
     gene            complement(50286..50564)
                     /locus_tag="KRH23_000358"
     CDS             complement(50286..50564)
                     /locus_tag="KRH23_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CD3324 family protein"
                     /protein_id="HHS5223657.1"
                     /translation="MSYKKAIHILPEELLELIQEYVDGEYIYIPRKSNNKKEWGSSTS
                     TREDLSIRNMQIYEDYQVGYDLKYLSEKYYLSLKSIQRIVLQEKRKDS"
     gene            complement(50872..51633)
                     /locus_tag="KRH23_000359"
     CDS             complement(50872..51633)
                     /locus_tag="KRH23_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase"
                     /protein_id="HHS5223658.1"
                     /translation="MKNKIEISMNNFVKNYHKSNNITTKWQELLFAYASAEDDMFQKL
                     KSVVGTSHAMPKDFLENGKTIITYFIPFDESVNNSNIGGFECSEIWARAYIETNMLIS
                     NLNDFLCEELEKIGANSYAIPGSYNFDSEKLVSDWSQRHVAFIAGLGTFGLNNMLITE
                     KGCCGRIGSIITSLELEPTKRPENEYCLYKHNNSCKKCVNKCVKEALKEDGFNRNKCY
                     EMCMINEKKYTYIGGCDICGKCIVGVPCSVINPSR"
     gene            complement(51802..53850)
                     /gene="bclA3"
                     /locus_tag="KRH23_000360"
     CDS             complement(51802..53850)
                     /gene="bclA3"
                     /locus_tag="KRH23_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like exosporium glycoprotein BclA3"
                     /protein_id="HHS5223659.1"
                     /translation="MLLIMSRNKYFGPFDDNDYNNGYDKYDDCNNGRDDYNSCDCHHC
                     CPPSCVGPTGPMGPRGRTGPTGPTGPTGPGVGPTGPTGPTGPTGNTGNTGATGLRGPT
                     GATGATGPTGATGAIGFGVTGPTGPTGATGATGADGVTGPTGPTGATGADGITGPTGA
                     TGATGFGVTGPTGPTGATGVGVTGATGLIGPTGATGTPGATGPTGAIGATGIGITGPT
                     GATGATGADGATGVTGPTGPTGATGADGVTGPTGATGATGFGVTGPTGPTGATGIGIT
                     GATGLIGPTGATGATGATGPTGVTGATGAAGLIGPTGATGATGADGATGATGATGATG
                     PTGADGLVGPTGATGATGADGLVGPTGPTGATGVGITGATGATGATGPTGADGLVGPT
                     GATGATGADGVAGPTGATGATGNTGADGATGPTGATGPTGADGLVGPTGATGATGLAG
                     ATGATGPIGATGPTGADGATGATGATGPTGADGLVGPTGATGATGATGPTGATGPTGP
                     TGASAIIPFASGIPLSLTTIAGGLVGTPGFVGFGSSAPGLSIVGGVIDLTNAAGTLTN
                     FAFSMPRDGTITSISAYFSTTAALSLVGSTITITATLYQSTAPNNSFTAVPGATVTLA
                     PPLTGILSVGSISSGIVTGLNIAATAQTRFLLVFTATASGLSLVNTVAGYASAGIAIN
                     "
     gene            complement(53917..54993)
                     /locus_tag="KRH23_000361"
     CDS             complement(53917..54993)
                     /locus_tag="KRH23_000361"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006486 - protein glycosylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat-containing
                     glycosyltransferase family 2 protein"
                     /protein_id="HHS5223660.1"
                     /translation="MITISLCMIVKNEEEVIGRCLECVKDIVDEIIIVDTGSTDSTKE
                     IVSKYTDMVYDFEWIDDFSAARNFSFSKASKDYTMWLDADDIILEADREKLLKIKESL
                     DTSIDIVMAKYNVSFDENGNPTLSYYRERLFKRSSNHKWVDPIHEVVPLFGEVFYSDI
                     AISHKKLHRQDPLRNLRIFEKMISEGKTLEPRHQFYYSRELYYNARYKEAIEGFTKFL
                     DSSRGWIEDCISACRDLATCYYLINDEKSALYSLFRSFEFDEPRAEICCDIGKHMFDR
                     QKYKEAIFWYKVALTRDKNDTNGGFKSNDCYGYIPSIQLSVCYDRLGESDKAIYYHEK
                     TKEIKPNDSAVLHNENYFSKFKNS"
     gene            complement(55305..55889)
                     /gene="clpP"
                     /locus_tag="KRH23_000362"
     CDS             complement(55305..55889)
                     /gene="clpP"
                     /locus_tag="KRH23_000362"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009368 - endopeptidase Clp complex
                     [Evidence IEA];
                     GO_function: GO:0004176 - ATP-dependent peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HHS5223661.1"
                     /translation="MSLVPHVIEQTGQGERSYDIYSKLLKDRIIFIGEEINDAIASLV
                     VAQLLFLESEDPDSDIIIYINSPGGSATSGFAIYDTMNYVRCDVSTICIGMAASMSAF
                     LLAGGTHGKRCALPNSEIMIHQPMGGAKGQATDVKIAVDNILKIKERLDKILSENTGK
                     SIEDIRRDTDRDNFMTALEAKEYGLIDYIMNRNE"
     gene            complement(55886..56368)
                     /locus_tag="KRH23_000363"
     CDS             complement(55886..56368)
                     /locus_tag="KRH23_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HHS5223662.1"
                     /translation="MKTNTDVIMEIIDYIEENLTENLNLDKIAYIANYSKYHLHRMFT
                     NVVGCTIHQYIQRRRLTEAARQLIFTDKYIIDIAITVGYSTHQSFTLAFRNLYKESPQ
                     VYRNKDEFYPIQQRFVLNLNHQIQSEKCISYANMNYKQRRDEINSYLNFNINCEVKVA
                     "
     gene            complement(56567..57982)
                     /locus_tag="KRH23_000364"
     CDS             complement(56567..57982)
                     /locus_tag="KRH23_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HHS5223663.1"
                     /translation="MWITINRNSNISLSRQIYCEIKDMILDGSLKFEQKLPSSRTLSK
                     ELSVSRNTVLDAYNQLIAEGYLETRNGYGTIVAKGISGHKVDFKLNDTFRDEKDLHTN
                     KQKNYIDFRSGVPELKLFPRKELSKLYKQILYDLSDSDFRYGSTAGVWVLRVEISKYL
                     FRTRGIRCNPKNIMIVSGSTQGLSLISQLLYKSNKKVAVEDPIHKGLLKVISSIGYSV
                     VGIKVDDKGMNTNLIKSIKGISFVYTTPSHQYPLGGILPIQRRLELIKCATENDYYII
                     EDDYDSEFRYEGQPISSLYELSPNKVIYIGSFSKILSPAIRVGFMLLPDNILESYKTL
                     KMYSDVHTETILQHVLAEFIGNGGLEKYIFRMKKLYNRKRKYLIKVLNTEFKNEFKIK
                     GEAAGLHIVAHFYNVKFTESLIHKIFEAGIKVYPIQQYAIENILEYDHEIILGYAHLS
                     FDEIEKGVKILSKIIHMNQGT"
     gene            58097..58765
                     /locus_tag="KRH23_000365"
     CDS             58097..58765
                     /locus_tag="KRH23_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase beta subunit-related
                     protein"
                     /protein_id="HHS5223664.1"
                     /translation="MLEISHKVKEIYPNIKFGVMVINITHSKPNKENFLVLKNSTIKN
                     IIEQHPEYNRKEKIKTEPVSSYIKYYKKFKKTYPVLLQLESILLKSKGIPDVGVTIES
                     MFLAELKNLLLTAGHDLDKMELPLKIELANGSEHFYGIGGKEHILTKDDLFLSDNIGI
                     LSSILNGPDNRTAITKDTKNIMYFVYGPDKISEKQIQDHLNDIKHYISSAFPDLKVNS
                     IDIF"
     gene            complement(58941..59459)
                     /locus_tag="KRH23_000366"
     CDS             complement(58941..59459)
                     /locus_tag="KRH23_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HHS5223665.1"
                     /translation="MNFVELAKKRYSCRNYQDRKVEKEKLEKVLDVARIAPTGGNRQP
                     QRLIVIQEKEGINKLSKAANIYDAPLAILVCGDKDKVWTRPFDGKQLTDIDTSIVTDH
                     MMLQATELGLASVWVCYFNPDIIREEFSLPDNLEPINILLMGYESKIPESPERHEKTR
                     VPLSEIVSYETL"
     gene            59611..59934
                     /locus_tag="KRH23_000367"
     CDS             59611..59934
                     /locus_tag="KRH23_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HHS5223666.1"
                     /translation="MKKCLDNYSCPIEATLALIGGKYKTLILWHLKDTILRFNELKKL
                     IPKATPKMLTQQLRELESDGLIIRVVYPVVPPKVEYSLSDFGKSIIPILDSMCDWGSD
                     YLENL"
     gene            complement(59939..60523)
                     /locus_tag="KRH23_000368"
     CDS             complement(59939..60523)
                     /locus_tag="KRH23_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1/PfpI family protein"
                     /protein_id="HHS5223667.1"
                     /translation="MKVLVFLAKGFETMEFSVFVDVMGWARNDYGHDIDVVTCGFKKQ
                     VMSTFNIQVLVDKTIEEVCVDDYDALAIPGGFEEFGFYDEAYDSSFLNLIREFNSKEK
                     IIASICVAALPVGKSGVLKNRKATTYHLKNGKRQRQLSEFDVNVVNEPIVVDKNIITS
                     YCPETAPHVAFKLLEMLTSKEQMDEVKLAMGFKL"
     gene            complement(60572..60838)
                     /locus_tag="KRH23_000369"
     CDS             complement(60572..60838)
                     /locus_tag="KRH23_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC ligand binding domain-containing
                     protein"
                     /protein_id="HHS5223668.1"
                     /translation="MAFIFINTDLSKSMKEFKKTILEYDTVLECHHISGEYDYLIKVL
                     AEDTSNLEEFISVTLKEIGGIQKANTTIVLSTIKEEFNTIKDIF"
     gene            complement(60893..61027)
                     /locus_tag="KRH23_000370"
                     /pseudo
     CDS             complement(60893..61027)
                     /locus_tag="KRH23_000370"
                     /inference="COORDINATES: protein motif:HMM:NF024804.6"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC family transcriptional regulator"
     gene            61909..63447
                     /locus_tag="KRH23_000371"
     CDS             61909..63447
                     /locus_tag="KRH23_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HHS5223669.1"
                     /translation="MSLLKVTNLSQCFMDKSLYEKANFDLFKGEHIGVVGQNGTGKST
                     LIKILLGEVVPDSGEIKWQPNINIGHLDQYAEINRDTTILLYLHTTFEELYKIEKEMN
                     LLYQKSAISENEQYLIKASDYQEQLIANNFYSIDNEINKIANGLGLDSIGMNRVVREL
                     SGGQRAKVILAKLLLSNHDVLLLDEPTNFLDKEHVEWLSNYLNTFNGAFIVVSHDFDF
                     LEKISTGILDIEFGMIKKYHGKYSEFLKQKSHLREDYIRRYQAQQKKIEKEETFIRKN
                     KAGVNSKIARGRQKQLDKIERIAPPSFIGKPNIQFSEIEISAQNALTITNLEVGYYYS
                     LLPKLNFSVDGGQKIVITGFNGIGKSTLLKTLVKDIPRISGNFQFSEQVKIGYYEQDL
                     KWENPDKTPLQIVADKYPKLNTKEIRRHLARCGVKEEHVSRSVSTLSGGEQSKVKLCC
                     MMLSPCNFLILDEPTNHFDAETKDALQNALKQFRGSIILVSHEEKFYKGWIDKIFNIE
                     KQLV"
     gene            complement(63719..64549)
                     /locus_tag="KRH23_000372"
     CDS             complement(63719..64549)
                     /locus_tag="KRH23_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HHS5223670.1"
                     /translation="MSIRDVTISNVKARVVNIKKQDSDTARLEYNKFLWRDFNMDTCF
                     NKKILLVDDEKDIVDLIEEVLINDGFKNIIKAYNGLDAISLCKVACPDVVILDIMLPD
                     IDGIEVCKKIREFSYCSILFLSSKNDDIDKILGLSSGGDDYITKPFSPREIAFRVKAQ
                     LRRQQYQSIVPSDSEVIKIGDITIDIEGNRVYKDRNEIELTGREYHLLSYMAKNVNKI
                     IGKERLYEQVWGVYSSICDNTIMVHIRHIREKIEDNPSNPKILITVKGLGYKLVNRID
                     "
     gene            complement(64881..66260)
                     /locus_tag="KRH23_000373"
     CDS             complement(64881..66260)
                     /locus_tag="KRH23_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA];
                     GO_function: GO:0042910 - xenobiotic transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006855 - xenobiotic transmembrane
                     transport [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HHS5223671.1"
                     /translation="MSDVYYSENHEQDNLYEQDNLLAQRFNLFTLLKFAFPTIFMMIF
                     MGLYTIVDTIFVSRFINTNALSAINIVCPIINLIVGIGTMLATGGSAIVARKMGNGDI
                     EGANKAFSLIVLSGVVIGVIITGIGIVFMDYIIIWLGASEVLIKYCRSYLFIILVFAS
                     ANILQVLFQCLFVTAGKPQFGLWLVLGAGCANIILDYVFIVLLQMGISGAALATGVGY
                     LIPTISGMVFFSKNKGLLKFCIPRLDKRILFEACFNGSSEMVGQLSTAVTTFLFNAMM
                     MKLIGEDGVAAITIIIYSQFLLTSLYIGFSMGVAPIISYNYGSENNTQLNHVFKICIL
                     FISVASLLVFIFSISCSPIIVEIFSQRGSRVYEIARSGFYIFSFSFIFCGYNIFTSSM
                     FTALSNGKVSAILSFLRTFGFITIGLLILPNMLNINGIWLAVPSAEILTLFLTIFCIC
                     KYKNRYKYM"
     gene            complement(66545..67339)
                     /locus_tag="KRH23_000374"
     CDS             complement(66545..67339)
                     /locus_tag="KRH23_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHS5223672.1"
                     /translation="MMKKNLKIIFMLLKMKLSKMMVFRFDFFGAFFVDSSLFILQLLM
                     FNSIYSHVDSIGGWQQGEMLIFIGTFSLINAINMTIFFFGIYDIPRKIQEGELDYYIT
                     KPLDPLFRLTFENINIGSSPLILASILIVLYGISELNSEITLVMIIIYIFMVLLMTLL
                     FYDVCIILRTVSFFVISSSAIMRLEDNLLPMNMKIPGVIYEGVFKVLFYLILPYGIMS
                     TIPTQILAGTITINGLIYSILIVFLFTLFMWRFWKLGMRHYKSASS"
     gene            complement(67336..68190)
                     /locus_tag="KRH23_000375"
     CDS             complement(67336..68190)
                     /locus_tag="KRH23_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHS5223673.1"
                     /translation="MSNYNEASSNDSMFYKFKQSIRRYYEVAKINFKVQLIWRFDVVV
                     NMVFTIVKILFAYILWKAIFGENKIVSGFTFNSMLSYYIISSFLAGIDMSKSTSEEIC
                     NRVKLGTFSKYMIIPINVQNYFIAKNFGMTCFYFVFNMISAFVWIFIFKIDFAFTSNP
                     VQILISILMIFLGFIFMMKLHFFIGILSFKFLEISFFRMIIENIVEFITGTMIPLVLL
                     PETIVTVMKVFPFYYTTYLPSMLLIGRNSNEAIQGLIILALWVLFFSVVNKVMYKRMR
                     TLFDGVGI"
     gene            complement(68177..69172)
                     /locus_tag="KRH23_000376"
     CDS             complement(68177..69172)
                     /locus_tag="KRH23_000376"
                     /EC_number="7.5.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHS5223674.1"
                     /translation="MSIIELNELTKSYRRFEKKAGFMGSVKSLFNRKYTEKTAISSFD
                     LKIEEGEFVGLIGQNGAGKTTLIKMLTGIIAPSSGEISVMGYYPNKLENNFKKQYAVV
                     MGQKSQLFFELTPADTFLLFKELYDISNEEYKKNLDYFIELFEVSDYLNVQVRTLSLG
                     ERMKMELIVALLHNPKILFLDEPTIGLDAIAQKQIRYFLKEVNETKGTTIILTSHYME
                     DIKSLCSRSIVVENSRKIYDGSTEKLFNHFQKYKKITVSFSNETNIVFPKDCKVVEQT
                     NHKISVIVPKERGNETIKWIFDKYDVKDVMIEEEDIGSIVERIYKKGSDEYYEQL"
     gene            69875..70831
                     /locus_tag="KRH23_000377"
     CDS             69875..70831
                     /locus_tag="KRH23_000377"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase domain-containing protein"
                     /protein_id="HHS5223675.1"
                     /translation="MENNTIQKQLRDLSKKIWHIYILNPEEENLKFIISLLDDNLALI
                     GTGKHEFYETLEEFIIGLEKDQTESEQIDFEIIDEWYSCTKVTDEAFIVYGTLWVIEK
                     DYLEKDIYVEMDTRFTMVYRVTDDMIKLIHVHHSIPNFDQMKDEYYPKTITEKAQEAL
                     AMANEFKLKSEKDLMTGLYNRHFFEVHIKEMLKTVSHGYFYIFDLDNFKQVNDIFGHV
                     RGDEILIHFSNILTKVFVNDAIIGRLGGDEFAVFEYSNQSKENVENKAKKVLELCLES
                     NSCSIGISKLENNSDTFQSLYKQSDYALYYSKRNNKGNFSWF"
     gene            complement(71233..72123)
                     /locus_tag="KRH23_000378"
     CDS             complement(71233..72123)
                     /locus_tag="KRH23_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5223676.1"
                     /translation="MKKNILTTMITMIIILMMSMTVMAEPYQEDETSSLKKQSANERN
                     QTNIGTMDGRVQTNAISKGANYDPKYPLKGMLTQLGLNTTGKEGWDLLYGGNPNGVEL
                     RADGKYYYINKGMEGLGFYAAALSGGSYQRIGFGKLDPIEVIADGNWISYKQAQDTLT
                     VIRNFLNSFDWRNASEMERANRAAKLVTEAKYADSKYCNIVYGNLVDKRGVCGSFASS
                     FHLLTRLMGMDSLSILNPSLNHAWNYIQIDGKWYRFDGSEISAFGGSLDFDYRKLKDA
                     TREMTTYYDAKALSILGFNQ"
     gene            complement(72301..72999)
                     /locus_tag="KRH23_000379"
     CDS             complement(72301..72999)
                     /locus_tag="KRH23_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5223677.1"
                     /translation="MKISSQYRSQYSFRYESNINNTRINESMVKKNETVGKDTYLSNI
                     MKQKQELNDRIRDLKYRQEVYTKKINDAIKNLCKSEIRETTNNFSNIEIGIKNSIIED
                     KNKSTMLDENSTYLNTNDEKESLITKESNEKIEEEILNDEKLEELEQKKDYKEDSNKK
                     EKVSEDLSLVGKTREELENMLKNFINLTQEEIMKLESRIEKLDKNAEEYKQNSKTNIF
                     DKTDEQKKHINVLI"
     gene            complement(73535..74602)
                     /gene="rsgA"
                     /locus_tag="KRH23_000380"
     CDS             complement(73535..74602)
                     /gene="rsgA"
                     /locus_tag="KRH23_000380"
                     /inference="COORDINATES: protein motif:HMM:TIGR00157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HHS5223678.1"
                     /translation="MNGMKQINLQDYGLNRNFITQSMEYHDLYLARIISQEKNFYQAV
                     CVNGVLFAEVSGKLRFEATIQSDFPTVGDFVILDRCNNKNGNAIIHHVLHRKSLFVRK
                     AAGKVNEEQVVAANIDIVFLCMSLNKDFNIHRLERYLSLTWESGAIPVVVLTKSDLCD
                     NVYRKLQVVNSIALGVDVVVTSSIEPDGYKQISKYIKPGCTVALLGSSGVGKSSLINC
                     LMGGEFLNTKEIRIDDDKGRHATTRRELFLISGGGIVIDTPGMRELGMWDVSEGLDKS
                     FADIEAYFGKCHFRNCTHTSEPGCAIWEAIAHQELSPKRWESYRRLKTEAVFADNKSE
                     YLAKKEKKFKNISKINKKIRR"
     gene            complement(74599..75000)
                     /locus_tag="KRH23_000381"
     CDS             complement(74599..75000)
                     /locus_tag="KRH23_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNHCP domain-containing protein"
                     /protein_id="HHS5223679.1"
                     /translation="MNYKNRKRAYYQENSCMDNFICKNCGCLVVPEGAGTQHRNHCPH
                     CLHSLHVDIIPGDRAADCDANMEPIGVWVRKNGEWAIIHRCTRCGHLSSNRIAADDNS
                     VKLMSIALKPLAQPPFPLERIIEKLEKEETE"
     regulatory      75796..75892
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            75946..76122
                     /locus_tag="KRH23_000382"
     CDS             75946..76122
                     /locus_tag="KRH23_000382"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5223680.1"
                     /translation="MFRDKMDRCTHMLTAYIGSSYDYCDFIDTQLDDFILEYGENVVE
                     SCLHQVMVLVSKYN"
     gene            76532..76672
                     /locus_tag="KRH23_000383"
     CDS             76532..76672
                     /locus_tag="KRH23_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5223681.1"
                     /translation="MSNQRKDFDITNDMFQESIPITTKIILEDMPSNDELNHVFSISK
                     NS"
     gene            76680..77072
                     /locus_tag="KRH23_000384"
     CDS             76680..77072
                     /locus_tag="KRH23_000384"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5223682.1"
                     /translation="MLKESWNFDIPIPNKEIEVFDTQDSINGDGQSYFIQGFSEKNFK
                     KVFNLKGGIVVSKDNINEIEKYIDKFKRDSVNINKSNKNKIEEDFKKYKLEVKKDDKY
                     IYKRNYENYVVLIIKKDEQKLYSLIWNQ"
     gene            complement(77549..78907)
                     /gene="rlmD"
                     /locus_tag="KRH23_000385"
     CDS             complement(77549..78907)
                     /gene="rlmD"
                     /locus_tag="KRH23_000385"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HHS5223683.1"
                     /translation="MLSKNEMYIVDIVDIGQGGVGVGKYNGITVFVEGGLIHDKVKVR
                     INKVKKNYAVGDIVEIIEKSPFRVKRVCSDNLRDCGGCQIQDLDYNKQLEMKTNEVKQ
                     VLSRIGKLEDVEVHDTIGMDNPYRYRNKAQFPIQKNNGIPIIGFYKKKTHDVISTEKC
                     VIQHEINDKIVKIIKTYIRAYKVSIYDEKTHTGLIRHLVTKIGFTTKEVMVVLVANGN
                     KLPYLKELASVLKENIPGFKTLVVNVNQKDTNAILGRENIVIYGDGKINDYIGDLVFE
                     ISPLSFFQVNPVQTKVLYDKALEYANLNDTDTVFDIYCGIGTISLFLAQKAKKVYGIE
                     IIDDAIKDAKINAKLNNIHNAEFYVGKAEEIVPKMYREGKTANVVVVDPPRKGCDEKV
                     LETIVSMNPERIVYVSCNPSTLARDLDYLNVHGFKCVEAQPVDMFPHSTHVETVAKII
                     KQ"
     gene            complement(79082..80842)
                     /gene="pyk"
                     /locus_tag="KRH23_000386"
     CDS             complement(79082..80842)
                     /gene="pyk"
                     /locus_tag="KRH23_000386"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004743 - pyruvate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0030955 - potassium ion binding [Evidence
                     IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HHS5223684.1"
                     /translation="MLNNVKKTKIVCTLGPASQSEEVLTQLMQNGLNVCRFNFSHGSH
                     EEHKERIDMAKKVREKLNKPVAILLDTKGPEIRTGNFEDPEVFLEEGQKFTITMKDIM
                     GTKEMCTVSYKGLAEDVKSGDSILIDDGLVGLRVKEINGEDIVCVVENSGIVKNHKGV
                     NVPGVKINLPAITPKDISDIEFGISQGIDYIAASFVRKASDVLAIREVLENNNATDIQ
                     IISKIENQEGVENLDEILKVSDGIMVARGDLGVEIPTEEMPIVQKMMIKKCNELAKPV
                     VTATQMLDSMIRNPRPTRAEVTDVANAIYDGTDAIMLSGETAAGKYPVEAVKMMATIA
                     KRTEETLDYDRLLKENGTNNVTVTDAISHATCTTAVDLNASAIITSTSSGYTARMVSK
                     FRPKSPIIATTNNEKTMNKLALTWGVYPVKSSVAGNTDEVIEKAIEAARQADYIDNGE
                     LVVITAGVPVGVSGTTNLIKVHVISEEIVQGIGVGTQTVEGKVRIIKNGNACVDFNEG
                     DILVSTATDAEMNNYIEKAGAVVTENGGMTSHTAIVGINLDIPVIVSAADITNLVKDG
                     EVVTVDASRGVVYRGSTRVL"
     gene            complement(80894..81853)
                     /gene="pfkA"
                     /locus_tag="KRH23_000387"
     CDS             complement(80894..81853)
                     /gene="pfkA"
                     /locus_tag="KRH23_000387"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006002 - fructose 6-phosphate metabolic
                     process [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HHS5223685.1"
                     /translation="MKTIGLLTSGGDAPGMNAAIRAVVRSAIYYGCKVYGINRGYKGL
                     LEEDLTEMNLSSVGDIIHRGGTILKSSRCEEFKTEEGRLKAVKILKKYKIDCLVVIGG
                     DGSFAGAQKLSDLGFPAIGIPGTIDNDLAYTDYTIGFDTAMNTIIDAIGKIRDTSSSH
                     ERVNIVEVMGRHCGDLALYAGLAGGAETIIVPEVEITVDEVALRLKTTQKRGKRHSII
                     VLAEGVGSASDLEKELKKESGADLRVTVLGHVQRGGSPTVSDRILASRLGVRAVELLL
                     DGKSARVVGIKENKIIDLEISEALAQKKVFDKEAYEMAKILSI"
     gene            complement(82062..85631)
                     /locus_tag="KRH23_000388"
     CDS             complement(82062..85631)
                     /locus_tag="KRH23_000388"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HHS5223686.1"
                     /translation="MNKDFAHLHVHTEYSLLDGFSRVKKLIKRAKELNMSSIAITDHG
                     CMFGVIDFYKTAIKEGIKPIIGCEVYTAARGLRDKDPNYDKYQGHLVLLAKNMEGYKN
                     LIKIVSTSYVEGFYYKPRVDMEELKKHNKGIIALSACLAGDVARALMNRNYEKAKQFT
                     LDYRDIFGEENFFLEIQDHNLPEQKEVNSGLVKLSKETGIPLVATNDVHYVNKEDSKI
                     HDVLMCIQMGKTLNDPNRMRFGSDEFYLKSREEMEELFPYALEAIDNTVKIADMCNVE
                     FDFNTIHLPKYDVPEGYTPETYLRELCFNGLKERYDNPSNEILERLNYELDVIEKMGY
                     VEYFLIVWDFINFSKENNIIVGPGRGSAAGSIVAYTLKITDIDPIKYSLLFERFLNPE
                     RISMPDIDIDFCYERREEVIDYVKRKYGDDHVAQIITFGTMGAKAAIRDVGRVLDIGY
                     NKVDKVAKEIPFALGMTIDKALDTNPNLKELYDQDPETKEIINISKQIEGMLRHASTH
                     AAGVVISKNPVDEYVPLYKHQDAITTQFTMTTLEELGLLKMDFLGLRTLTVIRDTLDL
                     IEKNRVIKNYTEKIDFSKMDYDDPKVYEMLSSGNTLGVFQLESAGMRSFMKQLKPDNF
                     EDIVAGISLFRPGPMDSIPAYIKNKSNPKDVTYLHEKLKPIMEVTYGCLVYQEQVMQV
                     VRDLGGYSYGRSDLVRRAMSKKKMDVMEEERQYFIHGKFDEDGNIEIAGCIRNGVEEE
                     IANKIFDDMIDFARYAFNKSHAAAYGVLAYETAYLKTYYPVEFMAALITSVMGNTDKV
                     VEYIRECKALEIDVLPPDINKSFSKFSVEGDNIRFGLAAVKNVGVNIINNIIAERESN
                     GLFVDLVDLVKRLDQKDTNKRVIESLIKCGAFDNISENRASLMAGYESLLESVSMDRK
                     KNVQGQISLFDAFGDSEEDSDFQQIYSLPKRQEYEERERLNLEKEVLGMYVSGHPLSQ
                     FEKELQEKTSMDNGKLNSLKEEEESYLQMNETDVIMGGMIVTKTIKTTKRNEIMAFIE
                     LEDLYGAIEIIVFPQLLQKYNVILNEDNIIYVKGTLSIKEGENAKLIAREIKDINDDT
                     DFADRNYNSGRTRNVENIKPESGKKLYLKIDSMSDTDTTNNIVEIAKQYPGNDSIYLY
                     PMDENINGKRKAYKMTGALTCICDEFINNLEELLPKDNIKVKA"
     gene            complement(85788..86735)
                     /gene="whiA"
                     /locus_tag="KRH23_000389"
     CDS             complement(85788..86735)
                     /gene="whiA"
                     /locus_tag="KRH23_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0043937 - regulation of sporulation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HHS5223687.1"
                     /translation="MSFSTETKNELARVISGNECCNIAELSALVKSGGSIQIVGYKKL
                     NLKITTELNSIARKVFKLLKKNFNINTTISVNKNQMLKRNNSYVLMVTSEMGSEMLLK
                     KLGILEDKEGFFTINKISENLIKHEGCKRAFIRGAFLGGGSISDPEKNYHMEFVTNNE
                     EFADSLKELINSLGFNSKIVARKNNHVVYIKESEQISDLLSIIGGHHALLSLQNTKIV
                     KEMRNNVNRIVNCETANLSKTVNAAVRQVENIKLIQETIGISSLPENLQEIAKIRIEY
                     EDMTLKELGEMLEPPIGKSGVNHRLRKIEEIATDLKKKS"
     gene            complement(86752..87177)
                     /locus_tag="KRH23_000390"
     CDS             complement(86752..87177)
                     /locus_tag="KRH23_000390"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016817 - hydrolase activity, acting on
                     acid anhydrides [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0009132 - nucleoside diphosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HHS5223688.1"
                     /translation="MREEVSAGGVVLFGNTILLLRKFNGDWVLPKGKVEEGENNQEAA
                     LREVSEETGVKADILKYLGEIHYTFKENWDENRAVHKTVFWYLMQAKNMDTIPQKEEG
                     FIDAKFIHLDRVVDLARYDDEKEIIKVALQEIKKRLKKN"
     gene            complement(87246..88352)
                     /locus_tag="KRH23_000391"
     CDS             complement(87246..88352)
                     /locus_tag="KRH23_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043743 - LPPG:FO 2-phospho-L-lactate
                     transferase activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gluconeogenesis factor YvcK family protein"
                     /protein_id="HHS5223689.1"
                     /translation="MAKLLIIVGILGWIALIVSLFIYKKAKNEKVKLFQRSIVENREP
                     NVVVIGGGTGQSVFLRGLKHTTQNITAIVTVADDGGGSGVLREDLGMLPPGDIRNCLL
                     ALANIEPTMNEVMQYRFTEGLLKGQSFGNLFLAAMNGLYGNFEKAVYKLSEIFAITGR
                     VLPVTLEDVNLVAKLENGNIINGESSIPEESKIQKSSIDKIFLNPKDVKPLKDVIASI
                     YDADIIIMGPGSLYTSIIPNLLVEGIVDAIKSSVAPKVYIANIMTQPGETEGYNVLEH
                     VNAIVKHTDENLIDYVIANNEILPEEMLDLYKQDGAEQVLLDKKQKDKLKEMGIKTVE
                     KNLIEIKNNYIRHDAKYISNIVIELALNHNYNKS"
     gene            complement(88364..89221)
                     /gene="rapZ"
                     /locus_tag="KRH23_000392"
     CDS             complement(88364..89221)
                     /gene="rapZ"
                     /locus_tag="KRH23_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HHS5223690.1"
                     /translation="MKFVIVTGLSGSGKSETMRALEDMGFYCVDNLPPALITKFAELC
                     YQPNSSIDKVALGIDIRGRKFFEALHESLNYLEKENYEYEMVYLDCNDDVLLKRYKMT
                     RRNHPLAKDMQIPEGIKMERKIMEPLKELSTCIIDTTNMKPKDLKEEIKKIYSSGEDN
                     PNLTISVVSFGFKHGILADADLVFDVRFLPNPYYVEELRAKTGDDKEVRDYVMNSKIS
                     EEFYVKLLDMIHFLVPQYIEEGKQHLVIGVGCTGGRHRSVTITNLIAEDLSNKGYRVV
                     KKHRDSMLR"
     gene            complement(89252..89965)
                     /locus_tag="KRH23_000393"
     CDS             complement(89252..89965)
                     /locus_tag="KRH23_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HHS5223691.1"
                     /translation="MKILADYHTHTLYSHGKGTIEDNVKVAISKGIKTIGISDHSYKH
                     IAYGVKKKDILKMREEVDYLNDKYTDINILLGMECNILDDKGNIDMDDKFIRDFDYIM
                     AGYHFGSTPTSLRSLLNHCNNYIFKTEKAKEYNTKAVINAISNNDIFIITHPGDKGDV
                     YIEEVAKTAKKTNTRLEINSSHSFLNVNQLNKIKGLENKFIIGSDAHCPERVGDFELA
                     MKTISDSNLDISLVENIII"
     gene            complement(89969..90883)
                     /gene="murB"
                     /locus_tag="KRH23_000394"
     CDS             complement(89969..90883)
                     /gene="murB"
                     /locus_tag="KRH23_000394"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008762 - UDP-N-acetylmuramate
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HHS5223692.1"
                     /translation="MNNQDIYINLLNILSKEDIKVDEPMKKHISFRVGGPADILVRPR
                     TEEQLKNVLKLVKKESIPYLIIGNGSNILIKDGGIRGVVIELADNFNSYEINDTRMTA
                     QSGALLSVLGKALQKQELKGFEFASGIPGTLGGALAMNAGAYGGEMKDIVKSVRLMDM
                     EGNIFELSNEQMEFGYRKSIISKNGYIALSAELELQEGNYDEIKSLMDDLATRRITKQ
                     PLNFASAGSTFKRPTGYFAGKLIEETGLRGLTLRGAQVSEKHCGFVVNQGEASAKDIL
                     DLIYVIKSAVYAKFGVMLEEEVKILGED"
     gene            complement(91156..91926)
                     /locus_tag="KRH23_000395"
     CDS             complement(91156..91926)
                     /locus_tag="KRH23_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HHS5223693.1"
                     /translation="MSKGFLTPGETAQATISAGIKKANISTQNAILLGLFGGAFIGFG
                     ALGSMIVSQTFGKIDPGVASFLSAMVFPVGLMLVVVAGAELFTGNTLMAIALMDKKIT
                     LGKMLRNWGLVYFANLVGSILLVALVFYSSTLTGDAATKAIAVAEAKVNSTIASMFLK
                     AILCNILVVLAVWMATASQDIMSKLASCWTVIMLFVLCGFQHSVANMFFIPMGMALGA
                     NITMVQFITNLVFVTLGNIVGGSIVVGGIYYLCYVKNS"
     gene            92244..93725
                     /gene="cls"
                     /locus_tag="KRH23_000396"
     CDS             92244..93725
                     /gene="cls"
                     /locus_tag="KRH23_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008808 - cardiolipin synthase activity
                     [Evidence IEA];
                     GO_function: GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA];
                     GO_process: GO:0032049 - cardiolipin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HHS5223694.1"
                     /translation="MFDISFFEMSIYEIAVTTIYIINFMVILNLIFREKRNINTTLTW
                     LLILVLIPALGFILYIAFGRNISKNNMFRLKEKDDKIIKSNILDTQVKLQSTSEIDSD
                     IHQHKDMIYALANSNNAHYTNNNDVWIYAESSQFFNSLLEELKKAKKYINIQFYIFKD
                     DKIGTEIIDILIDKAKEGVEVRLLFDAVGGRTLKNSTLSRLKESGVKVGSFFPSFLKI
                     VNFNLNYRNHRKIVVIDGKVGFVGGYNVGDEYLGRNPKFGLWRDTHTKLTGDCVIDLN
                     MRFILDWRYTTKEDLDLEKYFIEEDTNSNHPSENIGIQIVSSGPDISELDEIKYGYLK
                     MIQKARKYIYIQSPYLILDSTFIDTLKIACLSGVDVRVMIPSKPDHPFVYWASYSYAG
                     ELLKFGAKIYTYGQNAFLHAKTIVIDDSICSIGTANMDIRSFELNFEVNAFMYSSKKA
                     LEQRIIFENDILNSKEITLDIYNSRSTYIKIKESISRLLSAVL"
     gene            94043..94540
                     /locus_tag="KRH23_000397"
     CDS             94043..94540
                     /locus_tag="KRH23_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase subunit E"
                     /protein_id="HHS5223695.1"
                     /translation="MCDFISHNKQLFDELDIFIDSLATKEGALIQVLHEAQGIFGYLP
                     KEVQLHVARKLGVAPAKVYGVVTFYSYFTTEPVGKYKISVCLGTVCFVKGADKILSAF
                     EKQLGIKVGETTSDFKFSLEGLRCLGACGLAPVVTVNGKVYGKVKPDQVSEILDTYRE
                     LELNC"
     gene            94557..96443
                     /locus_tag="KRH23_000398"
     CDS             94557..96443
                     /locus_tag="KRH23_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-ubiquinone oxidoreductase-F iron-sulfur
                     binding region domain-containing protein"
                     /protein_id="HHS5223696.1"
                     /translation="MRKVNSFDELKVLADELKPNLSLRKNYSKENVLRRELLVCCDTG
                     CTSSNSLEIVSELENEIKKSGIQDKVSVRLTGCFGFCAQGPIVKVYPDNVFYVKVEPS
                     DAEKIVQSHLIRNTVVEELLYEEESLSKKVEEQEEMSFYKKQLRIALKNCGLIDPDSI
                     EEYIANDGYLALGKCLTSLTPQEVIAEVKTSGLRGRGGAGFPTGSKWEAASKNPAGPT
                     DKKFVVCNADEGDPGAFMDRSVLEGDPHSVLEAMAICGYAIGSDTGYIYIRAEYPKSI
                     ERLKVAIAQAEKYGLLGENILGTGFNFKLELKYGAGAFVCGEGTALMHSIEGRRGEPR
                     MKTYSSSKSGLWKSPTCLNNVETFANIPAIILKGGDWFANLGTEDSSGTKVFALGGKV
                     ENVGLVEVPMGTTLRDIVFEIGGGIPEGKKFKAVQTGGPSGGCIPTEHLDTPIDFGSL
                     SSIGSMMGSGGMLVLDESDCMVDIAKFFLEFTVEESCGKCTPCRIGTTRLLEILTKIT
                     EGNGTLQDLDDLENLAETIQTASLCGLGKAAPNPVLSTLQYFKDEYIAHVVDKKCPAG
                     KCQNLLSYFITDDCKGCTKCSRVCPAGCITGSVKEQHTIDTSKCLKCGACIDNCTFNA
                     IIKK"
     gene            96466..98247
                     /locus_tag="KRH23_000399"
     CDS             96466..98247
                     /locus_tag="KRH23_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent [FeFe] hydrogenase, group A6"
                     /protein_id="HHS5223697.1"
                     /translation="MSLVNLTINGKHVSAPSGTSILDAAKLINIKIHNLCHLHMNEID
                     KLDTCASCRVCMVETERGLVPACGTVIKEGMKVQTNSAKALNARRTIVELLLSDHPQD
                     CFVCEKNGDCELQTIAADLGVRKIRYQGSKSFAGKDTSTKSLVKDHSKCILCRRCETV
                     CNDIQTVGALSGVNRGFNTLVSTFFNSDMVETECTFCGQCISVCPTGALTEVDNVPKL
                     WDVLNKKEKTIVVQVAPAVRVAIGEEFGLEPGSISTGKMVAALKALGFEHVFDTNFGA
                     DFTIMEEATEFIERIQKGENLPILTSCCPAWVNFLEHNYPDKLNLASSCKSPQGMFGS
                     IAKNYYAPKILGINPEELYVVSVMPCVAKKYEASREELSESGILDVDLSITTRELAKM
                     IKEAAIDLPNLQDQDFDNPLGKSTGAASIFGASGGVLEAALRTSYEKITNKTLDNVNF
                     TNVRGLKGIREASIDVDGTTVNVCIVNTLKNARKIMDKVRSGECKYHIIEVMACPGGC
                     VGGAGQPYHHGNTEIVDRRANALYEIDRNKAIRKSHENPDLQAIYKDFFGEPNSDVAH
                     KYLHTHYFDKSCVYGECPQECACEEAK"
     gene            complement(98387..100183)
                     /locus_tag="KRH23_000400"
     CDS             complement(98387..100183)
                     /locus_tag="KRH23_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MutS-related protein"
                     /protein_id="HHS5223698.1"
                     /translation="MGIEYFSKLLESSTEKELLLSKKSNNISTARLISFLIVIVGLAI
                     GFYNKNIVGIFVGVLSIIIFIALLVIHSKVKEEETYFKSKSEVLNKYIKRFGDGWKEF
                     KIDGKEYLKDENSQAKDLDLFGRASLYQYICVANTSYGKNFLAKYLWNENPDENVILE
                     RQRAIKELLSKDDFSIHIQTLSNIIGKEQKNNSDISIESFIEYGENKNVYIPKWMHIF
                     TWGLPTATILSFIFCMLGFLPVLPVFLLFIIQLGFSGFGYPRLMQTLAPLFSFSRSIQ
                     VYEKMFEVLEKETFESAYLKELQDKLSKGSGVSRGVKQLNSIGNAVNLRYNQILYIIA
                     CGVLMWNYHCAEALERWKGIYGNQIRDWFESIGEFEALISLTVVSHVKENTCFPVIKY
                     EDTPRLKVEEVYHPLIAEKSVIANSIQLNSQTCIITGSNMSGKTTFLRSIGVNLVLAY
                     AGAPVCAKSFDATCMAIFTSMRIQDDVSQGISTFYAEILRIKSMIQYSLKELPMLVLV
                     DEIFKGTNSADRIIGASEAVKKLSKPWVISMVTTHDFELCDLSGSGDVEVVNYHFSEY
                     YVDDKIHFDYKIKDGRCKTTNAKQLMRMAGIL"
     gene            complement(100397..101326)
                     /gene="hprK"
                     /locus_tag="KRH23_000401"
     CDS             complement(100397..101326)
                     /gene="hprK"
                     /locus_tag="KRH23_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006109 - regulation of carbohydrate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HPr(Ser) kinase/phosphatase"
                     /protein_id="HHS5223699.1"
                     /translation="METSNKVSIREIIKELKLKVVYMPDDVDYYVYSQDINRPGLQFA
                     GYFDYFAYERIQIVGKTEYNFFGLMDSHIREEVLDRFFSYEIPALIISRDLEIKPDVI
                     EKAKKYKRILLSTNRNTTRLINRLSNYLDNKLAPHTTIHGVLVDIYGIGVLIKGESSI
                     GKSETALELIQRGNRLVADDAVEIRKLDESMLVGQSPELIRHFLEIRGIGIIDVRSLY
                     GVGAIKNSKMIDLVVHLEAWDETKYYDRLGLDKEYEEILGVNVEKLVVPVKPGRNTAM
                     ILEVAAMNFRQRGMGYDAAQEFTKKLSKLIDTK"
     gene            complement(101326..103143)
                     /gene="uvrC"
                     /locus_tag="KRH23_000402"
     CDS             complement(101326..103143)
                     /gene="uvrC"
                     /locus_tag="KRH23_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0009381 - excinuclease ABC activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HHS5223700.1"
                     /translation="MFDIQEHLKKLPSEPGVYLMKDKYDHIIYVGKAISLKNRVRQYF
                     QSSKNHTSKVKSMVKNIYKFEYIITDSELEALILECNLIKRYRPKYNVVLRDDKTYPY
                     IKVTTNEDYPRILKVRRVLKDKAKYFGPYTNITAVNDTLELISSTYPIRSCKIDIDKA
                     IKNKTRPCLNLHINKCLGPCTGNVSKEEYGKMIEEIIMCLSGKEEKLMELLKEKMNES
                     SMNFRFEEAAVYRDKIKSLEEMIQKQKIDATVSDLNQDVVAMARAHNEACVQVFFIRN
                     GKIVGREHFILEGVMDSPRASILSSFVKQFYNEQEYIPKELIIEDEIEDSSILEEWLS
                     SKKGQKVTIRVPQKGEKKSLVEMVRKNAVEYLEKFSDMNKRKYEKSIGALEELKQILN
                     LEKLPIRIEAYDISNIQGVDSIGSMVVYTNAKKDKKEYRRYKIKTVIGPNDYDSMAEI
                     VDRRLKHGNLPDLILLDGGKGQVSAVKKVLELNDVDIPLWGMYKDDKHRTKGLICKEK
                     EIELDKTTNLYRFIASIQEEVHNYAITYHRSLRNKALTKSILDDIQGIGEKRKKSLLN
                     HFKDVDAIKKATMEELLEVDGMNKSIADNVYNFFRKEEN"
     gene            complement(103402..106227)
                     /gene="uvrA"
                     /locus_tag="KRH23_000403"
     CDS             complement(103402..106227)
                     /gene="uvrA"
                     /locus_tag="KRH23_000403"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HHS5223701.1"
                     /translation="MEDKIIIRGAKEHNLKNIDLELPRDKFIVFTGLSGSGKSSLAFD
                     TIYAEGQRRYVESLSAYARQFLGQMEKPNVEYIEGLSPAISIDQKTTSKNPRSTVGTV
                     TEIYDYLRLLFARVGDVYCPTCGEKISQMTIQEIVDKMLDFPDRTKLQILSPIVRGQK
                     GTHKKVFDNIKKEGFVRVRVNGENYEVSDDIILNKNQKHNIEVVVDRIVIKDGIESRL
                     ADSIETAVKLSDGLVIAQIIDGEEILFSTKFACPEHGIGIEELSPRMFSFNAPFGACD
                     VCNGLGESKEVDPELVVPNKDLSIKQGAVAAWGSTGVNDDTYYSKMIKSLAEHFNVSL
                     TTPFKDLPDDFVEELLYGKDNIIVEFTYESKFGGTRNYKSYFEGVIVNLERRYRETNS
                     DYMRDKIEEYMAERPCPKCKGMRLKKEVLSVLVDGKNIMEVTNLSVNELIDFMENINL
                     TEKQRFIAHEIIKEIKGRAMFLRDVGLDYLNLSRKAGTLSGGEAQRIRLATQIGSALV
                     GVLYVLDEPSIGLHQRDNDRLITTLRHLTDLGNTLIVVEHDEDTMREADYVIDIGPGA
                     GIHGGEIVAQGTLDEIIENENSITGQYLSGKKQILLPETTREGNGSFIEIVKASENNL
                     KNIDVKFPLGKFTCITGVSGSGKSTLINDILYKGVASKVNRLKQRAGKHKEIKGIESI
                     DKVINIDQSPIGRTPRSNPATYTGVFDFIRDIFASTNEAKARGYKKGRFSFNVKGGRC
                     EACKGDGIIKIEMHFLPDVYVPCEICKGERYNRETLQVKYKDKTISDILDMNVEEAVE
                     FFENIPNIKRKLETLMDVGLSYIKLGQPSTQLSGGEAQRIKLAAELSKRPTGKTLYIL
                     DEPTTGLHMADVDKLIQVLQRLADTGNTIIVIEHNLDVIKTCDYVIDLGPEGGDKGGT
                     IVATGTPKEVSKVDGSYTGQFLKKYFS"
     gene            complement(106246..108216)
                     /gene="uvrB"
                     /locus_tag="KRH23_000404"
     CDS             complement(106246..108216)
                     /gene="uvrB"
                     /locus_tag="KRH23_000404"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HHS5223702.1"
                     /translation="MDFKIKSDFKPTGDQPEAIKSIVDSINRNEKFSTLLGVTGSGKT
                     FTMANIIQQVKKPTLIMAHNKTLAAQLYSEFKEFFPDNAVEYFVSYYDYYQPEAYVAH
                     SDTYIEKDASINDEIDKLRHSATASILERRDTIIISSVSCIYGLGDPKDYKELMLSIR
                     PGMQRDRDDVIKRLIEIQYERNDINFTRGTFRVRGDILEIFPASNDEKAIRIEFFGDE
                     VDRITEIDYVTGKIVGTRNHVVIFPASHYVTTPERIEKAIVEIENELQEQIKFFKEND
                     RLLEAQRIEQRTKYDIEMLKEIGFCQGIENYSRHITGRSEGERPYTLMDFFPDDYLII
                     VDEAHVTIPQVRGMYAGDRSRKTSLIENGFRLPSALDNRPLNFQEFEGNINQMLFVSA
                     TPGPYEIQHSETIAEQIIRPTGLLDPIVEVRPINNQIDDLVGEITKTIEKNERVLITT
                     LTKKMSEDLTNYLKEIGIKVKYLHSDIVTLERTEIIRDLRLGKFDVLVGINLLREGLD
                     IPEVSLIAILDADKEGFLRSETALIQTIGRAARNENGRVIMYADRITDSMQNAIDETK
                     RRRDIQNLYNEEHNIIPKTIQKNIRDSIEATKVAEEEVVYGISDTDDKDEIRANIDKL
                     KSEMMEAAQNLQFERAAELRDKVKQLEEKLEK"
     gene            complement(108403..109665)
                     /locus_tag="KRH23_000405"
     CDS             complement(108403..109665)
                     /locus_tag="KRH23_000405"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline phosphatase family protein"
                     /protein_id="HHS5223703.1"
                     /translation="MTKVIVLSVDSLFEKDLEFVKNLPNFKSILENCSIVKNINCVYP
                     TLTYPCHTSMVTGVYPKKHGIYHNEKFDPNKENKDWYWYSKDIKAKTIIDVAKENNLT
                     TSSVLWPVMGANPNIDYNIAEIWAPSREDDPRETFERSSSKVIMDGIYNRHCHYIDWK
                     LEPNMDLFGVNCSVDIIKEYKPDLMLIHLATLDHTRHNYGLFNDEVDKALKMNDKWLG
                     DIIQATKDAGTYKDTNFIILGDHGHLRVDKVINPNVLLKSNGFIKVENGEVKDFDAYV
                     NSSGISAQIIVNNLDRLTELRELLEEFKEELFIENIFTKEEASNLGLEGDFEMVIEGL
                     EGISFGNDFEGSIIKDSDIKDYKFAVATHGHLPTKGNRPPFIAFGPNIKGGVVIEEGD
                     LRAHAATILKMFNLKLDGVEKEAFDFIM"
     gene            complement(109728..111032)
                     /locus_tag="KRH23_000406"
     CDS             complement(109728..111032)
                     /locus_tag="KRH23_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HHS5223704.1"
                     /translation="MKLKRKLATGLAITLLLGSLVGCSNSNDANASKGEKTDSNITKI
                     DFWAPLGGTNGETAQKMVDQFNSEHKDVQVNMLKQKDYYENATKLQAALTSKDQPDVT
                     LLEITQTGTFASAGALVDMSKYFDKTYQERFFSGLLTNSYYEDKFVGMPFNRSTPILY
                     INKDMATKAGLDPSGPKSWEELKDYASKMTNKSEDTYGFETPIDIWFYEAMVMQSGGE
                     ITNGKKVAFNNEAGQAPVKFWQDMMKAGIMKMPPGEDYNAWDVAKQDFVNGKVGMIFT
                     STADLAGLMQQTEGKFEISTAFLPKNQKYATPTGGANLVMLEGGTDKEKEASAEFIEW
                     MTQTDKIVQFSSSTGYLPTTEDATNSEKLQTLYKEKPQYKVATDQLQYAVALPMLNGY
                     KEATDKLMDEIKKGLTDLNANPKDVVSKGTSAMQAVIDKTNK"
     gene            complement(111063..111923)
                     /locus_tag="KRH23_000407"
     CDS             complement(111063..111923)
                     /locus_tag="KRH23_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HHS5223705.1"
                     /translation="MDIIQPIKKDKVDIKKIASKSIEILILLLLSAIFIFPFIWMLST
                     SFKNPQEMMQLPPTIIPNDIVLENYSTAWHSGPFFRYLLNSVFVTGSVLIVQFLVMVP
                     AAYAFSKIKFKGEKMLFGLLLVGLMIPPQVTFLPVYMMMSKFGFINTYVPLIIPFMTS
                     SFGIFLLRQNFMQISDEIIEAAKLDNASDLKIMFRIMVPMAKPAVITFILFNFIYHWN
                     NYFWPLVMTNTDAIRTLPIGVALLKSSEGITAWNVIMAGNIILILPIILVYIFANKKV
                     KEAFMYSGIK"
     gene            complement(111967..112836)
                     /locus_tag="KRH23_000408"
     CDS             complement(111967..112836)
                     /locus_tag="KRH23_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HHS5223706.1"
                     /translation="MKKQFNKAYLYITPAIIGTLLFIVYPIIKTISLSFKSGSLLSST
                     FENVGLNNYTELLKNPEFIQTITNTAIYTFFMVTISISLAIVLAVWLNKNSIIHNLTQ
                     SIIFTPHVISLVSVAVLWLWIMEPQYGFLNWILSTLHLPTSKWLSSESSALMSLILIG
                     IWKTLGYNILIVLSGLKSIPNYIYEASKLDNANKITNFFKVTLPLLSPTIFFLMITTT
                     TASFQVFDEISIMTQGGPVGSTNMLSYYIYESGFIYYDIGQASAASMFLLAIVMIATY
                     ANFRLLSKKVHYQ"
     gene            complement(112820..113890)
                     /locus_tag="KRH23_000409"
     CDS             complement(112820..113890)
                     /locus_tag="KRH23_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHS5223707.1"
                     /translation="MADIRLENVTKSYNKKNTVIENLNLTIEDGSFTVLVGPSGCGKS
                     TTLRMIAGLEDITSGRLKIEENDVTKTDASKRDIAMVFQNYALYPHMTVRENIEFGLK
                     NKKVEKEKREKLITEVIDVVGLREYLNVKPGNLSGGQRQRVALARAMVKNPKVFLMDE
                     PLSNLDAKLRNQMRTELIQLHQKLKSTFVYVTHDQVEAMSMADKIVIMNKGKIMQIGS
                     PKKIYQNPKNLFVAQFIGSPCMNILDIKNDIKFGFRPEKATLESINIDGKNDDVFSLF
                     GKVVTKEVLGNETIYCLSVLNREIRVKTENDIFDIGRTLRISVLEKDLYYFDKNGERI
                     EDVKVCKSMYSKIKGDIYEKAI"
BASE COUNT        36492 a        19771 c        13040 g        45031 t
ORIGIN      
        1 atattgtttt tgtaaattaa atttaaatat ttattaaatt tatttttata agaaaatatg
       61 gcaataagct ataaacaata catcatttta attaatttag atgtatatac tataaaaatt
      121 aaataaaaat agagactaca ctttaccatg tagtctccat ctttctggtc atatttagaa
      181 attcacattt attgttactg cttttccgcc tctatttact gttatttttg tactagcacc
      241 ttttgagaaa gtatacaact ttttatttaa atcattcata cctgttatat ctgtatctcc
      301 tactttagtt ataatatctc ctacctttac tccagctttt tctgctgatg aaccagatat
      361 tacttctgca acataaacac ctttatcagt acttaatttt gtacctgttg ctgcttcata
      421 atttgataca tctgtacctt ttatgcctaa agttactttt tcatattttc catttttgat
      481 tacttcttca actatactct tagctgtatt gattggtatt gcaaatccta atccttctgc
      541 ttgagaagct tttgctgtgt ttataccaat tacttgacct ttttgattta acaatggtcc
      601 tccactattt cctgcattta tacttgcatc agtttgtaat aaaccagtca tattagtttt
      661 ttctgtttgt atagttctat ctaatccact tattatccct tgagtaactg ttttttgaaa
      721 atctaatcca agaggattac ctattgctat tgatatatct ccaactttta ctttgtcact
      781 atcagcaaat tctgctggtg ttagtccagt tttatcaacc ttaactatag ctaaatcaag
      841 ttgttggtca aaccatacta ctttacctga agttgttgaa ccatcattga ataatacatt
      901 tacacttgta gcttgaccat ctgatataac atgagaatta gtaagtatat atccatttga
      961 atcaactatg attccagttc ctacaccttg tgtttcagtt ggtattgcaa acatattact
     1021 agtatcaaca ctagttgttg taatacctac aacagatggc gtagcttttt ctgcaactgc
     1081 ttgataaata ttttgactct taccatcatc atttacaact atcggcgtag aacttcctgt
     1141 agatttactt actaaattgt ccttaactaa aattattgtt agaaaactac taagtattga
     1201 acttattata gcaactaata ttactaaact tatccctttc tttcttcttg acatctcata
     1261 ccactcccta tcttaatata atataaatta tcaaaatata tttttcccaa tttttcataa
     1321 aaaaaatgaa atcatctatt ttgagtaaac tcctttttga tgatttcatt atattatttt
     1381 aatcttaatt aaaccttaac tatttaaaat tatttaagtc ttttttctag ctcttccttt
     1441 tctttttcat aacctggttt gcctagtaaa gcaaacatat ttttcttgta agcttctact
     1501 cctggttggt caaatggatt aactcccaat aaatatccac ttattccaca agccttctca
     1561 aagaaataaa ctaaatatcc aaaattatac tcatctagtt gaggtatatt tattactaaa
     1621 ttaggtactt ttccatctgt atgagccaat agagttcctt caaaagcttt atgatttaca
     1681 aaatctacag tcttacctgc taaatagttt aaaccatcta agtctacttc ctctgaactt
     1741 atagttatat ttctcttaca gttttcaaca ttaagtactg tctcaaataa aagccttttt
     1801 ccatcttgta tgtattgacc catagaatgt aaatctgttg agaaatctac agaagcaggg
     1861 aataaacctt tattttcttt tccttcactt tctccataaa gctgtttcca ccactcactt
     1921 acataatgta gttgaggttc atagttcact aataactcta catcttttcc ttttctatgt
     1981 aaaattgttc tagcaacagc atatctataa ctatcattac tttttaagtc aggattttga
     2041 aatgcttctc tagcatcatt tgcgcctttc atcatagcat caatatcaag tccagcagca
     2101 gcaataggaa gtaacccaac tgctgtcaat acagaaaaac gaccacctac atcatctggt
     2161 attacaaaag tctcatatcc ttcttctgta gctaactgtc taagtgcacc tttacttgca
     2221 tctgttgttg cataaattct ctttcttgct tcttccttac catacttttt ctctaagtaa
     2281 tctttaaata ttctaaaagc cagagctggt tctgtagtag ttcctgattt agatattaca
     2341 tttacagaaa tatcctttcc ttcaattata tctaataaat ccataatata tgttgagctt
     2401 atattatgcc ctacaaaata tacttctgga gcctttcttt gctctttttt aagtccattc
     2461 ctaaaagaat gacttaccat atctatagca gctctcgaac ctaaataaga gcctcctata
     2521 cctattacca aaagaacatc tgagtctgat tttatcttat cagcagattt ttttattctg
     2581 tcaaactctt ctttatcata atttttagga aggtctatcc atcctaaaaa agtatttcct
     2641 aaaccagttt tattatgtaa catgtcgtgc gcaacatcta catatggttg catgacatct
     2701 atttcgtttt gacaaaaaaa ctctgtagct ttactataat caaaatttat ttttcccatt
     2761 taaatccctc ttttcagcat attcgtttta aagagattat aacacaaaat ataggtgttt
     2821 tttttaaaag tttgccacaa aatcatacat atctcatcat ttattatcag gaaatcgatt
     2881 cttctaaata ctataactat gtataaattt taaaatttta gtcaaataaa tttacaaaaa
     2941 aagaaactct aaacgtatca tttaaagttt ctcttttatt tatcctctat tttaaatttt
     3001 atattatttt aaattaatta tttttaatca tttcctaatc tcttcgctat aacttgttgt
     3061 gctatattga cagcatggtc agatattctc tctaaattac ttattacgtc taaataaata
     3121 actccatttt ctatactaca tagattattg ttcaatctat acatgtgatt agctctacaa
     3181 gatttctcca ttatatcaac ttgttcttca atttttataa ccttgcaagc taaatcaaca
     3241 ttatcgctcc tcattgattc taatgcataa gtatatgctg aaacaactct attatacata
     3301 acatcaagtt cagattgtcc ttcttctgag aaataaatat ttgaatctat tgcaacttgt
     3361 gataattcag ctatattttt agcgtggtca ccaattcttt ctatatcatt gactgtatta
     3421 aataaagtat ccacaacttc tcttgaatca tcatctaaag ctgcttttga aagtttaagt
     3481 aaataattta aaatagcttt ctgtaaatca ttgattaatc tctctcgcct atatgtctta
     3541 tctatttttt cagttgaatg ttctactaaa gcttccatag atgcatttag gctttccttc
     3601 gccttctcac ccatacgaag tgcttctttt atcgtatttg caagagctat agaaggagtt
     3661 tctatcattc tatcatctat atatttaata gttttagttt catcttcatc tatatcacct
     3721 gctctatcag gaacaagctt tatagctagt tttataataa gatttgtaaa tggtaaaagt
     3781 atcaatacag atattatatt aaacaatgta tgtgtattgg ctatttgtct tgcaacattg
     3841 cttgggtccc aacttgtaac catgcttact actggtttat tcaagaatat taagaatatc
     3901 accgttccta aaacattgaa gattagatgc atcatagctg ctcttcgtgc atttttgtta
     3961 gcaccaatac ttgataacag tgaagttaca catgtaccaa tattttggcc ataaagaatt
     4021 ggcagtgctg ctgataatgg cactagacct tctgctgcca gtgcaaccaa catacccata
     4081 gatgcacttg aactttgtat tattgctgta atcccaaatc ccaataataa tccaagtagt
     4141 ggatatctac caaatgtaac aagtaagtca gtaaatcctt gatagtctct tagtggttcc
     4201 actgccatct tcataaaatc catacctgta aataatatac caaaacctat aagtatttcg
     4261 gctatatttt ttattctagg cttatttcca aataaataaa gtataatacc tacacctaat
     4321 gctactgggg ccataccagt taagtcgaaa gataccaatt gggctgtaac agtagtccct
     4381 atattagcac ccattataac tcctattgcc tgttttaaag tcattattcc tgcatttacg
     4441 aaaccaacaa ccattacagt agtagcactt gaactttgta ttactgctgt aactcctgta
     4501 cctaccaaaa ctcccataaa taggttacta gtaagtagtt ttattatctt ttttagcttt
     4561 gtcccagcag atttttgaag accttctccc ataaggttca taccatataa gaacagacct
     4621 aatccaccca ttagacttat tataatgttc aaattatttc ctccttgtaa agagattact
     4681 gtatctaaaa attttataac ctattgtatt ttatcaaatt ataggagtga taatgttaaa
     4741 ttcatgttaa atattaaaaa atcattaagt ttatgttaaa tttttgtatt attggtgtat
     4801 ttttgtatta ttttttctgc acattttata ccatcaactg ctgctgtaac tataccacct
     4861 gcatatccag caccttcacc acatggatat agattcttaa tactcactga ttctaaagta
     4921 ttttcatctc ttactattct tattggtgat gatgacctag tttctactcc cgtcaaaaca
     4981 gcatcataca ttgcaaaccc attcaatttt ttatcaagag atataaacgc ttctctcata
     5041 gtctctgtta cgaagctagg caaacattca cttaaatttg taagtgtata tcctggtcta
     5101 tatgatggct caacacttcc taaattcaaa gaagtcttat tgtttataaa atctccaaca
     5161 agctgaactg gtgcattata attttttcca cctaattcaa aagctaattt ttcatacttc
     5221 tgctggaaat gaacacctgc tagtggatta tcactcttaa aatcttctgg cgttacattt
     5281 actaaaaatg cactatttgc atttatttta tctcttgcat gttcactcat accatttgta
     5341 actatttcaa aatcatttga tgcagatgct atgacactac ctcctggaca catacaaaaa
     5401 gtatatgctg ttcttccatt tgaaacatgc tctataagtc tataatctgc agctcctaac
     5461 ctaggatgat tataaaaatc cttgtactgt gctttattta ttaaatcttg tggatgttca
     5521 actctagctc ctattgcaaa aggtttttga actattttta tacctcttga atacaacatt
     5581 tcataagtat ctcttgcact atgtccaaca gctaatataa ttgtatctgt atctattttt
     5641 tcagtatcat ttattattac agattgtata gaatcatttg atacaactat atctgttact
     5701 tttgaattaa atctaacttg accacctaaa cttattattt catttcttat atttttaact
     5761 acatttttta atatatctgt tccaacatgt ggcttatgtg agtataatat ttcatctggt
     5821 gctccaaact gaactaactc ttctaatact tttctacatc gtatatcttt tattctagtt
     5881 gtaagtttac catccgaaaa agttcctgct ccaccttctc caaattgaac gtttgaatta
     5941 ttttttaatt ttctagttgt ccaaaaatca cttatatctt tggttctact gtctacatca
     6001 agacctcttt caagtatgat tggttcataa cccatttgag ctaaaagcag acctgcaaac
     6061 aaaccagctg gtccactacc aattaccaaa ggattattct ttaatttttt atcacccaca
     6121 ggtacattta cgtatctgat ttcctttatt tttgttacat cttttatttt tgagttaagt
     6181 attttatttt catctttaac ttctacatct acagaataaa caaattccat ttttcctttt
     6241 tttctagcat ctatagattc tttatatata ctatatttga ctaagttttt ttcttttatt
     6301 tttagcttct taagtataac atcttttaat aaagatatat ctttatcaat tccaagtttt
     6361 acattagata ctcttaacat attgttttcc tctcttagat tgtaatataa aaaagctagg
     6421 gttattccta gctttctaca aatataactt ctatattctc ttttactaga ttttctaccc
     6481 aaatctcatc tagcacaaaa ttctttattt tgtttacaac aagtgtttta tctaaatctt
     6541 ttttcaagtt ttttactaag accattgctt caactgattt atgcaatctt tcaacataca
     6601 gagaattaac tttaatcaat acaaccctta attcacatac atataacttt tcactaccta
     6661 aggtgatttc atcatcatat tcatatacac taaattcata tgtattttca taaggtgtta
     6721 tattttctat tcctatatag tccatttatt tatccttttt tagttataag acctcttata
     6781 accttcatat tattaaacac cttttctaag aagttctctg cttcttcatt gtctaaaagg
     6841 tttatttcaa ggttttcgtt ttctacaata cctttagatt tacagtactc tttagcaata
     6901 tttattagtt catttttttt atccatagat aaatcaaact ctttatagtc tattattata
     6961 tattgtttgg tatcaggtga tacaccatta ttatatccta tttctatatg ataaataact
     7021 gcatatattt cttctccgtt gtacacaggt acagctgggt tagattttat aaagttcgtt
     7081 gatacagcaa ttgcatttcc taaactaaga ctcattatta atacctcttt ctaaacatta
     7141 tacatatatt atactataga ttctttatct atgacttaaa gctttttata attaattaag
     7201 atatttttaa atccttgtat ctctttccta gtgtactaga gcttatatcg tatttctttg
     7261 atatttgaac ttgagttata ggttgtcctg cttctttttt aacatagtat tcaacagcag
     7321 ctgcccaacc attttcagct ccttttatat tttcatgatt tttcttatat tcattccaaa
     7381 actctataca tgcatctata ttttcttttt ctacattttc tttaagagta tctaaaactt
     7441 tacattcttc ttcagctaat tcattttctg aattaacttt tgtatcgttt ttatctcttt
     7501 ctctctttaa atattcagct atacttgggt ctaaaagctg ttgtatatac ttgtatagta
     7561 tatgtgtatg ataaattaag aacgacttca tatctttgta tacatcttga tattgattga
     7621 atagattcat aatatccttt aaaattatat ctttaacctc atttgatata cttatagtta
     7681 tatctatcaa tatgttagtt ccttcaatat caactattct agctatcata caacttccga
     7741 ttttaaaact tctcagaagt tttacatctt ctgtacaaag ttcatttcca cttaaacagt
     7801 cctttaatac tatttttcca gcagaaactt cttttacctc ataaatactt acgtatgatt
     7861 caaacatact ttttaatatt gatacttctg attgacttag gtttgcacca ttttcttcaa
     7921 gaaaaccaac tgtcataacc tttttatttt ccattatgtg gtcttgtatt aaataagtat
     7981 taaaaaatct ttcaaatttt tcatttacac tatcattttg cattatataa aacatttctt
     8041 tagctttttc acattcttct ttaaacttat cctgtcttga ataatcatat aactttgaat
     8101 ataaatctgt atattgtttt tgtgaaagtt cagtttttct gcatgctctt tctgaaacaa
     8161 tatctttatt taaacaacat ttcttgtatt ttttgccact tccacaaggg catagctcat
     8221 ttctccctaa caatatgact tccactccct tattattaaa ttaaagtaca atttgttatt
     8281 ataccatttt tttattaatc aatctatagt ataagtaaat attctattaa attcacttat
     8341 attttggtac aatatattaa ctttaattag gatttcgata aaatcatcaa caatccctct
     8401 tgtagaaatg aattatcgta aaactaattc ctctataaaa ttttattaat tgataatagt
     8461 tttttacttt atctattctt ttttgttata tgactctaac tgtcatttta cattcaacaa
     8521 tattgtcttt ttcttgttta tattcatttg gaatattttg agcatcaaaa ttattgactt
     8581 ttaatttatt aatttctatc ttttcaagtt tattatttag tcttaacttc ttcattacac
     8641 cttcaagttt caacacattt gcaagttctc cattaacttt tatttctaaa ttaacttgtt
     8701 ttttattgtg attatctaaa ctactttctt gattaatata ttctacattc acaatatctc
     8761 tcagttcatt ttctactaat aacactatat ctttatttgt ttttttatct aaaaatgagt
     8821 tattaaaatt atttttcaat tcttcatttt tatttaattc aacactttct atatatttat
     8881 catctatatg cttattatcc tttatttgat aattatcttg attatttatt ttatttatta
     8941 tattttgctt ttcattcttc aaactagtta ggttttcttc caaataactt actgctatat
     9001 cacttgccaa tataataact aatattaaca atattttaag tagatttttt tctctattat
     9061 ttaatctcaa aaataatcac ccatctaact ttttattcta aatctataat attctccatc
     9121 tcttacaata ctgtctatgt aataatattt tatgtacttt attttcctta aattgtttaa
     9181 aacatctaaa tcactacaca caccttccat ctctagctta tttttatcta tcgatatttt
     9241 agtaatacta tttattccaa ttgtttcata tatttttttt atttcattaa gttttatttt
     9301 agaaaatttc tctctagttt tatctgttgt tggtaaagtg ttctttgatt tatccactag
     9361 cttattttga cttatataat cttcaagttc atttatagat ttcacataca taaatgattt
     9421 aaataaaata cacgttaaaa ttaagactat tattatttta tagattttat tacatggttt
     9481 agttttttta aatccattaa gaaaatttat tgttttatcc actttcactt aaataatcat
     9541 tcctatatta cttatataat ttatcctatt gtcttctaaa tctgcatcaa aattattttc
     9601 tacttttact ttatctttta atcttaatgg atttacttca atagatttat ctgtatattt
     9661 aaagtattct tcaataaaac aattttctat accatagtaa taaacatact taaaatccct
     9721 taataatctt tttataaact catatgattt tccctctttt gatagcaagt atgtttctct
     9781 tattttttta tcttttgtta tatttataat taactgactt tttttacatt ctataaatac
     9841 cccttcttct gaaaaattct ctattaaatt taagtttata agcttttgta atatatcaaa
     9901 atttatattt atagtctttg gattcatatt tagattttct gaaatgttct taattaattg
     9961 aataatactc tttgggaaaa gaattacttg tatattcaat ttatcatttt tagaatttat
    10021 aactttatat tttattgaat agttatttat gtttattgga atgtattgtg ttatttcaaa
    10081 ttcaatcatg cttaatatgt ctcttttttt cttagtattt agaacttcaa catttctaat
    10141 gactatatcc tgaatttgaa tgttaaagta taaattttta tataatattt ttgatttacc
    10201 aatctcttct tttacaaatc taactacatc ttctatatat ttaatcttct caatcgaatt
    10261 actatcattt tttatatcaa agttaatctc ttttataatt gatttatcta taaaaacttt
    10321 tttatgactt tttcttaaaa atacaagcct tatataatca tcatttattt ctaagtttag
    10381 aattttttta attatagcca tctccttctt aaataaaaat aattttaaaa cttacagcaa
    10441 tcaatataaa atattatttt ggataaaatt gcttagaatt tatatttacg cttatatctg
    10501 ttccgctatc atttatgaca agttcgaatt tacctgatgt actctgagga actggaacag
    10561 tatttaggta tcccttttcc ttcaatgtct ctacacttag agagtctatt gtcttttcat
    10621 catcattaat tgccatgcta gctgcggtta ctatattagc agcattcgta tagtctgcat
    10681 ttaatttggc actttcttga accttactat acttaactaa tgctatacta gatataacgc
    10741 ctaaaatagt tactactaca atcatttcaa caagtgtaaa tccttttcgt tttttattta
    10801 tcaaatttat caattaaata ttctctcctt ttcaaaagtt tcatctaata aaatttattt
    10861 ttctctctaa aaattagtaa ttgcatcaaa cataggaaca accattgcta aaataaaagt
    10921 accaataatt aatcccataa atacaattag cataggttct ataaatttca ttatttgctc
    10981 tattttgtta tttaattcat tttcataaaa tttatttatt acatttagac ttttatctag
    11041 tttcccactt tcttctcctg tatttgccat tgaaataaat aattttggaa aaacatttgc
    11101 taaattcaaa gatttaccta tactatttcc tttttttata taattattag aaatctttaa
    11161 cctttcataa ataaattcgt tgtctataac actagctgac atatctatag cttccacaat
    11221 ttgtattcca ctgctaatta aaacggacaa tgcccttgaa aatcttgttg tagctactaa
    11281 ctgattaatt ttttttataa aaggtatttt gaattttaac gaattaataa atttttttat
    11341 attatcattt gttataaaga aataaatgct tcctattgaa aacaatataa aactaaatat
    11401 tatataagct aagttatttg taaccactgt agatattccc attaaaactc tagttattaa
    11461 aggtggttca attccattgt tggtaaaaac cacctgaaaa ttaggtatta caaatacgaa
    11521 tataaacaac attgataaga tagataatat tataagtatt attggatata ttgaaatagt
    11581 tattattttc atttttaatt tgtattcttt atcataataa ttagataaat cactcattat
    11641 tatatctaag tttccactag tttctcctgc ttttatcata cttataaaga atttagaaaa
    11701 tatacctgtt atttgaaatg attctgctat tgagttacct ttttgaatat gatttgatac
    11761 tatactaagc aaattcttta cttttttact tgactgactc tcaatgattt caaatatttt
    11821 tgtaatttca catccagatt ccagcaatat gcctatctct ttgcaaatta ctctaatttc
    11881 tttatcactg attctattta atactaaata aaacttttct aaattataaa atatattttt
    11941 agataatctc atgtactata ataccttcca aattatatta attacaatta aataaactta
    12001 atattttcta atttaatgca tttaatttta tttcacttaa atataattta tactcaaaca
    12061 tcttaattaa aatagattaa ataaagacaa ctgaccaaac gaagtttaac tatacaattc
    12121 agttaaatca tttcatttac tactaaacac tcttctaatg tcgttatttt ttcatttatt
    12181 agtcttttac aactatcttc aaatgttatc attccattat tttgtgccac atctttaata
    12241 gtactagaat cctccatatt tcttatacat gtctttatat catcattaat ttctaagatt
    12301 tcataaattg ctgttcttcc aaagtatcct ttatcattac atttttcaca ccctacagct
    12361 accttagtat ttacatctcc actaaaatta tcttttatca taatctcatg gctacaatga
    12421 ttgcagactt ttctaaccaa cttttgagat ataacaccta taagagaggc atttaaaaga
    12481 tatggtggta tttgcatttc tagtaatcta gctatggaag atactgcatc attagtatgt
    12541 aaagtactta taactaaatg acctgttata gctgctctta ctgctatctt agctgtttct
    12601 gcatctctta tttctccgac cattattata tctgggtctt gtcttaatat cgctctaaga
    12661 cctacatcaa agctcaaccc tacttttgaa tttacttgaa tctgacttat gccatccatc
    12721 ttatactcta caggattttc tatagtcata atatttttat ttattccttt taaatcattt
    12781 aataaggaat atactgttgt agtctttcca ctacctgtag gacctgtcac taataatatt
    12841 cctgctcttt tatttattat acgatttata gattttatag cttcctctga aaaaccaagt
    12901 tctaatttgt cttttaaaaa agtatctcta ttaagtatcc tcaaaactat tttttcacca
    12961 tagacagttg gtattgatga aactctaatg tcaattaaat ttccacctaa ctttatatcc
    13021 accctaccat cctgaggaag ccttttttct gttatatcca ttgatgcctt taattttata
    13081 accgtagaca atgatggata gacatcaact aaaaactttg atacttcctt tagttctcca
    13141 tctaccctca ttctcactat taaatgttct ttaaatggtt ctatatgtat atcacttgcg
    13201 ttttctttta tagctttttc taaaagattt tcaaataatt tttttgcata atcctcatca
    13261 agttcaaagc tattataata tttttcaatc ttttcactta taagttcttt tttctccttc
    13321 ttcaatataa tttctttacc tgtagctaat ctcaagtcct gtagagcata aatatcctca
    13381 tcttctattt ctacaactaa attatcatct tgaaactcaa ctggaaatac attatatttt
    13441 tttgcaagtt tttctggtat taacattggc aaactgcttt tctctaatat aatcttaatc
    13501 accctttata tactttaatt tattaggtat attcattttt ttcatagaga tattttcttc
    13561 agtttttatg cttattttca ttggataatt ggtttgtatg ctatctaaat atttactacc
    13621 tttatctaca taattagata gtttctcctt atctccaatg cactttattt catatggttg
    13681 tgctacagga actccattta tatttatatg gcttcctgca agtacaactt ctgaatattg
    13741 attaattctt tgaccattta tttctatgta ttttcctccg tttactttta attcatttat
    13801 aacttttaca agaatcttat tatagtctat actattagct atattccctg ttttttcatc
    13861 tatagcatct atacttaata ttatcccact accctttaca tctgaatatg atagactatc
    13921 tctaagtgtt tctatttctg atatttcttc agaatttttt tgattttgtt tcattgaatt
    13981 aatttcttta tctaacttgt ctttctcttt ggttaattct tttatagatt ttcttgtcat
    14041 ttttatttct tttcttattg acttgtcttt gcttgtataa actgtttctt cattgctata
    14101 atctctaaat atggttccaa caagtatacc taaaatagta cttgctagta ttataaacac
    14161 atattgtttt ttcatactgt attgctcctt acaaatttat ttttatatga taattttctt
    14221 taattaaata ttaaacattt acatatgctt attatatcaa agttatatat taaaattcat
    14281 ctttagtata taatatcata cattgaactc ctatcactaa tttaccaata tcaagtatgc
    14341 atttttagat gttcttaaaa ttatataaac tttcaataaa cattattgtg atattataaa
    14401 aaaacataaa ttaggaaagg aaataataat tatgaaaaac aaataatgac tttggagatt
    14461 attaatatca ttttttagca aaaaaaagta aaatggcata gcctcaaagc tacaccaatt
    14521 tactaaaaat tatatcatta ttaacattaa ttttaaacat atgcgtttat aagttttcct
    14581 catattttaa aattctttta attaacttat ctcttaattt ccctacttca tcaaatctca
    14641 tattaggact atagtaactt tctataatat catgtttaga cttggctctc ttaagattta
    14701 gtactgccca acaaattaaa tcatctaaaa ctttttcatc aaatttaata tcttcttcat
    14761 atttaagtag tttttctcta tttaaaaact gatttaaatc aattgtatct tcttctttaa
    14821 aagtcgtact tatagttatg cctatatcta aatcagttaa tagtacagtt tcaattttct
    14881 ctggaataag tggataatga taaacttcta catttaaacc tttttcaata gctttcttat
    14941 atactttgtt taataatgta gttttcccag ttcctatttc tccatctaaa taatagactt
    15001 tctttacatc ttttaaaatg ttttctgtat aatctaaaca ccctacagga gttatagctg
    15061 aaccaaataa atgcttttct ctttttagat ttcctgtgct tttaactcca tcaaataacc
    15121 tttttataaa ttcttctgtg accaaattta ctttgccata atccatacaa tcagaatatt
    15181 tttcttctat gtctctaaag attggttctg ctgattttaa aaacttaaat gctcttttaa
    15241 atgaattact aatatcttta tcataaactg atatttcttg tttattcttt tctaattctt
    15301 ctgtattcca gtaatcacct aaattaatta tctcatccaa agctccaggt agctttgggt
    15361 ccatagtatg tggggcagtt gcatccataa gtaccacgcc taatttcttt ataactaaac
    15421 catccaacga acttgggtca gaaggacaat gatataaatc aatatcatat cctctatgca
    15481 aaaactcttt ataaattttt ttcataagtg aggattttcc tactccaggt ccacccttta
    15541 aacaaaaaac tctttttaca ttttcaggaa ttatatagtc aaaaaaagaa tatgagcctt
    15601 gtgatgtatt tccacccggg aatgccttct ttacctttcc ttccatatta gcgcctcctc
    15661 ataatttaca atatctctta attaagatat tcatattata agaattttat tacagctttc
    15721 tgattttgac aaatttaaaa cttaccatct aatactaata acaggttaat tttatctaat
    15781 tattatagat tctcatactg tgccttattc tatctataaa tacaatttaa gtgtccatat
    15841 tgaaatattt gtattgtaat acagctggat attacttaaa tccaattgtt tccattataa
    15901 ttttatgtta aaataatatt acaaaataca tctgtttttc ttcataaacg ggtgaaattc
    15961 cctatcggcg gtaaaagccc gcgagcctta tggcataatt tggtcatatt ccaaagccga
    16021 cagtaaaatc tggatggtag aagaaaatag tatatgagta cctttatgta attttacatg
    16081 agtaatctat acaaatcctt caactaccgt atttattcat gaaattagac acattcaagg
    16141 tacctaatat acaggtgctt tttttgttgt ttattttaca attatatcgt acttataaaa
    16201 tctattaaga ttggagtgtt atcatgaaac aaaaatggat agtattgatt atcatctgta
    16261 ttggtgtatt tatgtctact cttgatggaa gtatactaaa tatcgcaaat cctacaattg
    16321 ctgctgactt taaaattaac atgtcacaaa ttcagtgggt tgtaacagct tatatgcttg
    16381 ttgtaacagc tactatgtta tttttcggaa aacttggcga taaagtaggt tcaaatcgtc
    16441 tatacacatt aggatttttt atatttacaa taggttcttt tatgtgtagt atgtcaaaca
    16501 atttatcaac attaatttct tcaagaatct ttcaggcagt tggagcaagt attttaatgg
    16561 ctactgggct tggtatagtt tccaatgcat ttccagcaaa tgaaaaagga aaagctatag
    16621 gaatcactgg agctgtagtt ggtataggaa acatgagtgg tcctgtaatt ggaggtataa
    16681 ttttagaaca ttttggatgg ccttctattt ttattatcaa tatacctatt ggtattatag
    16741 cagtctttct tggcattaaa tttctaccta aacctgtttt ggatgaacaa aacaagagct
    16801 ttgatattcc aggtcttcta cttttcgcat cttgcactac gcttatatta cttgcaatga
    16861 atgagaaggg taatacaaga ttgtatttag gtataacagc acttataatc ttcttattgt
    16921 tggcattaag agaagtaaaa tttgaacaaa gctttattga cctacctcta tttaaaaata
    16981 gaaactttac tgtaggcaat atcattggag tcgcttgtta ttttcctcaa atggcagtat
    17041 cttttctact tccattttat ttagaacaat taaaaaattt atctcctatg atggctggtt
    17101 atgtaatgac tgtacatcca cttattatgg tacttatagc acctattgca ggttcacttt
    17161 ctgataaaca cggtgcaaaa aacattctaa cagcatcttt ttcatttatg accatctcac
    17221 tagttggaat ggcactttta aaagcagatt ctccattgta tcttttaatt gtatgtttag
    17281 ttatttttgg acttgggcta ggagcattta gttcaccaaa caatagtagt attttagcag
    17341 atgttcctcc tcaaaaacag ggatacggag gcagttttct tgcaactatt cgtaatttat
    17401 catttgctct tggaacagca ttttttagta gtttttttgc acaaagtctt acatacaatc
    17461 aaaagtttaa aagtcacaca tcagcctatg ttatagctag caatcagtct tattggattg
    17521 cagcatcagt atgttttata gggcttatac taactgtttt ctttatgaga aaaacagata
    17581 aatctatttc ttaaatgcta tttattgctg actacataag tcaataattt tttagttgaa
    17641 ctaatttata ctaattttcc cataccttac taaaatttat tagtatttag caaaattact
    17701 gatatttatt gtttataaac aataaggatg ccaaaaaaag ttcattaaaa ctattttaag
    17761 gcatcctata ttttgcttta atattaatat aattaaaact aactattatt acatttatta
    17821 ttcaaataaa tcttatgtca atatttaaca ctttaaattt aatctactgt tatttcatat
    17881 ccatgttgat tgtattgatt tacaatctct tcccataatt cttcaacacc agtctttttt
    17941 agtgaagaaa caggaattac tttttcacta ctttccattt gcaatttttt tcttattata
    18001 cttatgtgtt tttgatattg tcctctagat attttatctg ccttagttgc aataactaca
    18061 cagttatatc caaagtgctt tatccattca tacataagct tatcatctgc tgtaggctca
    18121 tgtctaatat ctacaagtag gaatatagaa cataactctt gtctactttc tagatatctt
    18181 tccattatac ctccccactt ttctttttca gacttagcta tctttgcata tccatagcct
    18241 ggaaggtcta caaaataaaa ttcattattt attagataaa aatttatagt tctagttttt
    18301 cctggtgttt gactggttct agcgaagttt cttctgttaa gcaatgtatt tattattgat
    18361 gattttccaa catttgacct accagccaat gctatctctg ggattccttc tgctggatac
    18421 tgtgatttat tcacagcact catagttatc tctgaacttc taattttcat tattttcacc
    18481 actctttaat aaagcttgtt ctaatacttc atccatatgt tctacaagca caaactccat
    18541 tttttctttt acattttctg gtatttcatc taaatcagct tcacattctt taggaattaa
    18601 tacttttgtt ataccagctc tatgagctgc taataacttt tctttaactc ctcctactgc
    18661 taatactcta cctcttaaag ttatctctcc tgtcattgct atatttccag gcacaggtct
    18721 tttagtaagt gctgagatta ctgcaagagc catagttata ccagctgatg gtccatcttt
    18781 tggaacagca ccttctggaa tgtgtatatg aatatcattc gtcttataaa attcagggtc
    18841 tatatcaaac ttgtccacta ttgaccttat ataagagata cctgtcttcg cagattcctt
    18901 cataacatct cctaattttc cagttaatac aatttctcct ttacctttaa gtacgtttac
    18961 ttctacttca agtgtaactc caccaacttc tgtccatgca agaccattta ctaatcctat
    19021 ttgagggtta acttctgcaa gttgatactt aaacatgtct tttccaagat atgtctctag
    19081 gtcagactta tttataacaa cctcttcaag agttgggtct tcaacgtatt ttttggcaac
    19141 ctttctacaa atcttaccaa tagttctttc tagtgttctt actccagctt ctcttgtata
    19201 atggttgatt atacttctta aagtttcatc atctattttt ataaagtttt cttttaaagc
    19261 atgttcttta atctgttttg gaagtaggta tttttttgct atatttaatt tttcttcttc
    19321 tatataccca gatacttcta ttacttccat tctatctaat aatggtcttg gtatattacc
    19381 tagactattt gctgttgtaa caaatagtat ttttgataaa tcaaaaggta tttctaagta
    19441 atggtccaca aaatccttat tttgctctgg gtctaatact tctagcattg ctgaagctgg
    19501 gtcaccttta taatctgctg ccatcttatc tatctcatca aataagaata caggattttt
    19561 tgtttgggct tcttttaccc cattaattat tcttcctgga attgaaccta cataagttct
    19621 tctatgacct cttatttctg cttcatctct aactccaccc aaagatattc ttacaaattt
    19681 tctatttaat gctctggcga ttgattttac tatagatgtc tttcctgttc ctggaggacc
    19741 aactagacat attataggcc ctttaagtga cttagcaaga gttcttatag ctagatactc
    19801 tagtattctc tccttaactt tttctaatcc ataatggtct tcatctaata tatcttttgc
    19861 cttagttata tctaatttat cttttgtctc tttattccat ggcaatgaga atatagtatc
    19921 taaatagttt ctacttacag atacatctgg agacatagaa gatatttttg aaaatttatc
    19981 tatctctttt tctattttct ctttagttgt cttaggtgct tttatttttt taagcttttc
    20041 tctatactca tctgcttcag agtttatatc ttcttcttca cctaattctt tctgtatagc
    20101 ttttaattgt tctctaagat aatattcttt ttgaacctta ttcatctgtt tttttactct
    20161 taaagttatt ttcttttcta tttttaatat atctatttcc tctaataata tagaataaat
    20221 aagttcaagt ctttttctaa tatcaaattc ttctaatatt tcttgttttt ggcttgattt
    20281 tagatatatg tttgcagcta tcgtatctat aaatctatct acatcttcta tatcagctaa
    20341 agatattaat atttctggtg ataccctatt tccaatattt atatactctt caaaggcatc
    20401 aaatacattt cttacaaatg cttcaatttc aacttctgtt tcactatcca aattatcact
    20461 atcaaatact atttcttcta ttactgctct gaaataccca tcttcttgtt ctattttctt
    20521 tactctaccc cttgatacac cttcaaccaa aacacgaact gtatctcctg gtaattttat
    20581 catttgctta actttacaga ttgttcccac atgataaaaa tcctcttctc ctggctcatc
    20641 tacctctgct tctttctgag aagttaaaaa tataagttct tcatccatca tagcttggtc
    20701 taaagcttta agagatatct ctctacctat atcaaaattt aatatcatat atggaaatat
    20761 agctaatcct cttagaggaa ttaatggtaa ttcatgatct attttagtat aattttgttc
    20821 catcaacatt actccttttc tagtctaatt gctttgcttt taatattata tatttgaaca
    20881 agttaatttt caacattaat gataaattct tagaatacta tcatactata ttatcttttt
    20941 attatgatat aatattaata ttagtatact tagatgttat ttatcttttg gaggtttcta
    21001 ttatgttgaa attgttttta acctttttaa aaattggtgc gtttacattt ggtggtggat
    21061 acgctatggt tcctcttata caagatgaac ttgtaaacaa acaaaaactt ttagagcagg
    21121 aagaatttat tgattattta tccatagctc aaagttatcc tggagtactg gcagttaata
    21181 tatctgtatt attaggatat aaactttatg gtataccagg ggttcttata tgtaccttag
    21241 gctctgcttt accatcattt tgtatagtct tagtcttatc gtatctatac tttaaaaatt
    21301 catcatctaa aattttagat ggatttttta aaggagttgc gcctgttgta atagctctta
    21361 tattgtattc ttttacgagc atgttcaaga aactaccaaa gtctaaaact aacatactac
    21421 tattaattat agcagtttta tctgttggtg tattcaatat aagccctatt tatttaataa
    21481 ttggaggagg tgtatatagt ctatgtcaga aataatacta ctcttcttaa tattccttaa
    21541 aataggggca tttagttttg gtggcggtta tgccatgcta ccatttatcc agcaagaatt
    21601 tatatctaaa tatcacttta taactaatca agagtttttg gatttacttg ctatatcaca
    21661 atctacacca ggtcctgtag caataaatag tgctacattt gtaggattta agactgctgg
    21721 cttctttggt tctctagccg caactattgg tgttacaatt tttgcattaa taggtctaac
    21781 tattatatca aagttatttt ctaaatttaa aaataataaa aaggtagaaa acttattgac
    21841 agttcttaga ccaattactc taggattcat attatcagca gctttttcat ctgccaaaga
    21901 agttaattgg gacttatatg ggataattgc atttatagca tcattttatc ttttatataa
    21961 aggaaaaatt ggttccattg caattgtatt cgtctttggt attctaggta tattactcac
    22021 atttttataa taatgatacc tattttatat ttagcatatt aacataaaaa aaggagcttt
    22081 taaagctcct tttcatcatc ttatgcactt tcctcttgat ccttaagtac tatgatagga
    22141 tttactgagt cttcgttcac agatttctct gttactataa ccttctttat attatctcta
    22201 gatggtactt caaacatagt ttccatcatt acgctttcaa ctatacttct aagtcctcta
    22261 gctcctgtat ttctttctat ggccttttta gcgattgcac gaagagcacc ttcttcaaat
    22321 tctagctcaa catcatctaa ctccaataac tttttatact gttttactag agcattttta
    22381 ggttcctgta atatctgcat taatgcatct tcatccaaca actctaaagt agctaaaact
    22441 ggtattcttc ctataaactc tggtattata ccatatttta ataaatcctc tggaagtact
    22501 ttttcatata gcttccctaa atctaattct tttttacttt ctattttagc tccaaaacct
    22561 agtgttttat ctccaccacg tttttgaatt atcttctcta atccatcaaa agctccacct
    22621 aatataaata atacattagt agtatctatc tttaaaaatt cttgatgagg atgttttctt
    22681 cctccttgtg gtggaacatt tgcaacagta ccttctaata tttttagaag tgcttgttga
    22741 acaccttcac cactaacatc tctagttata gatgggtttt cagattttct tgcaatctta
    22801 tctatctcat ctatatatat tatacctctt tcagcttttt ctatatcaaa atcagcagct
    22861 tgaataagtt ttaaaagtat attttcaacg tcttctccaa catatccagc ttcagtcaat
    22921 gatgtagcat ctgccattgc aaaaggtaca tttagagttc ttgctagagt ttgagcaagt
    22981 aatgtctttc cagaacctgt aggtcctaat aaaagtatat tactcttttg aatttctata
    23041 tccttactac tagatttttt actgtatatt ctcttataat gattataaac cgcaactgat
    23101 aaagcttttt tagctttttc ttgacctatt acataatcat ttagaatctc catcatttcc
    23161 tttggttttg gtaaagatgt agtatcctca tctatagtat cttctatctc ttcttgaata
    23221 atttcgtcac aaagttcaac acactcgtca caaatatata catttggacc tgcaattaat
    23281 cttcttactt gatcttgatt tttaccgcag aatgaacact ttaattgtcg tttttcttca
    23341 tatttagaca tattaacacc tctctctatc tacggtctct ttgtaaatac ttcatctatt
    23401 aaaccatatt ctttggcttc tagtgcactc atgaagttat cacgttcagt atccatttta
    23461 attttttcta atggctgacc agttctttca gataatatct catttaaagt ttcttttatt
    23521 tttaaaattc tctttgcatg aatttctata tctgttgctt gaccttgagc tccacctaat
    23581 ggttgatgta tcattatttc actatttggt agtgctagtc tttttccttt tgctcctgct
    23641 gccaacaaga atgctcccat agaagcagcc atacctatac atatagtact tacatctggt
    23701 ttgatgtatt gcatagtatc atatatagcc attccagaag ttatacttcc tcctggagaa
    23761 tttatatata aatgtatatc tttgtctggg tcttcagctt ctaaaaataa tagctgtgct
    23821 actataagcc ctgctgtggc atcgttaact tgatctccta agaagattat tctgtctttt
    23881 aatagtctag aaaaaatatc ataagatctt tctcctcttc ctgtttgttc aacaactaca
    23941 ggtactaatg ccatggtttc ataccccctt tattctatat aatttacagt agcttttttt
    24001 aagctactgt aaattattat acgcatttaa ctaaattata tttgcacatc attatatact
    24061 aaacatttca taacgtcaac tatattagtt agcgtttatt ttattaagct attgttgcat
    24121 tatcaactaa taaatctatt gtttttctta tttttatttg accttttata tcttctttgt
    24181 cggcatctct taaagaagct tctatttttt ctacttccat attgtaagca gaagccattt
    24241 tttctaactc agccttaaat tcttcttctg ttgcttcaat tccttcagct ttagttattg
    24301 cttctaatac taaagaagac ttaactaatt ttttagcatc ttcttttctc tcttctctta
    24361 attcttccat agttctacca gtcatctcta gtaattgttg taatccaaat ccttgatatt
    24421 gtaattggta gttaagttca tttaacatat tatctatttg atgttgtatc ataacttctg
    24481 gtatttctat ttctgtattt tcagcaactt tttctactac tgaatttcta gtttctgcat
    24541 ctgctctatt tttagcttct tcttctaact tagctcttac atctgctttt aattcatcta
    24601 aagaatcaaa ttcactagta tctttagcaa attcatcatc aagtgcagat aattctttta
    24661 cttttacatc atttattttt acattaaata caactggttt tccagctaaa tcttgtgagt
    24721 gatattcttc tgggaaagta acattaactt ctacttcttc accagctttt ttacctacta
    24781 attgttcttc aaatcctggt ataaatgtgt ttgaacctat aactaagtta taattttcac
    24841 ctttaccacc atcaaaagct acaccatttt caaaaccttc gaagtctatt atagctgtat
    24901 ctccatcttc taaagctttg tcttctacac ttactaatct ggcatttttt tcaaccattt
    24961 cttgtagttt agcatcaaca ttttcgtcac ttacagtatt ctcaacctta gctatttcta
    25021 tacccttgta gtttcctaat tcaaactctg gtttaacttc tacattaaga accataacca
    25081 acccattgtc tttacttatt tcttctatat ctaaatctgg attgtctatt gggtctatgt
    25141 ctaattcctt gatagcttct ggataaactt ctgggaataa tatttctata gcatcattgt
    25201 agaatatacc ttttccgtat tgagtctcta taacaattct tggagcttta ccttttctaa
    25261 atccaggtat attgtattta tttctgcttt tattataagc cttatttact gctgcttcaa
    25321 atttattgtt atctactgtt atttttaaag taactttatt accctctttt ttaattagtt
    25381 ctgctttcat ccttctaatc ctcctagtga tatttatgta atacccgata acggtattat
    25441 aattcattct atttataatt caaccactta attatatcac ataagttttt ttatttacaa
    25501 gtgttccatt aatatcgttg tacttatttg ataaaattta attttttgag cgttttttgc
    25561 cattttttta gataaataca cctttatatg cgtatttctt caatttttat gtcatcttct
    25621 tctatatcca taatgacaaa acttttatac gatactcctc ttggaagtga agtgcttcca
    25681 ggatttatgt aaagtacacc atctttaatt tctctaaatg gggtatgggt atggccaaat
    25741 ataactatat cagcatcaac ttcagttgcc tttttttcta acatattagt tccatatttt
    25801 acaccatact tatctccatg gcataagaat atggttttat ttgccacttc aaagacaact
    25861 tcttcctcaa cagcatcaaa gtcacaatta cctttaactg caataatacc tacattagtc
    25921 atgctatgaa tatatcttga atcagtaaag ttatctcctg catgaattat taggtcacat
    25981 tctttcaaat atggtattgt tttttccata tttttaatca tcatatgtgt gtcgcttact
    26041 atgcctattt tcattacttc actacccttt ttataaactc ttgtttcata agttttagtg
    26101 cgtttgctct atgactgatt gaatttttta taacactagg tatttcacca aaagtcttat
    26161 catatccttt tactataaat aagctatcat atccaaaacc atttttacct ttttcttcaa
    26221 atcctatcat tccttcacaa attcctctta ctacaaattc ttttccatca ggaaaaacta
    26281 ctgctattgc agagacgaat cttgcatttc ttttgctcat tggtacattt tgcatagctt
    26341 ttaacagttt ttttctattt tcttcatctg ttgcatgttc tcctgcatat ctagctgaat
    26401 aaacaccagg ttttttgcct aaagcatcta cttctaagcc agaatcatct gatattgcta
    26461 taagtttagt cttttttgct attgttctag cttttatcaa cgcattatgc tcaaatgttt
    26521 ttccatcttc tactatctct atacctgcta aatcaacatc ttttaaagag tacactttat
    26581 attcaaaatc ttttaagatt tcacctattt cttctagctt atgaacatta ttagtagcaa
    26641 tcactacttc attaccataa tccataccca atatctcatc tgatatttca cctaaagctt
    26701 ctctttgaag ccttattaat tctttattcc ctttttcacc taactctaac aataaattta
    26761 aatctgctct cgaaaaaggt ttctcttctc ctgtcccctg tacttctaca aactcacact
    26821 tatcagtcat tattatattc atatctacct gtgctttaga atcttcttca taacataaat
    26881 ctagcatgtg tattccattt acaataccaa cactaattgc agacacaaaa tttgttattg
    26941 gcatctcttt tattgtcttt gctttatata atttatatat tgcttctgca actgctacaa
    27001 atgcccctgt tatagatgca gttctagttc caccatctgc ctgaatcaca tcacaatcta
    27061 cccaaatagt tctttctcct aatttattca agtctacaac agaccttatt gctcttccta
    27121 ttaacctctg tatttcttgt gttcttccat caatttttcc cctagatgca tctcttatct
    27181 ttctttgttg tgttgctctt ggtagcatag aatattcagc atttatccat ccagtaccac
    27241 tatttcttaa aaaaggagga actttttctt ccactgatgc agtgcatata acctttgtct
    27301 ctcccatttc tataagaaca gaaccttctg catactttgt ataatctcta gttatcttta
    27361 caggtcttat ctgttcgtta cttctatcat aacttctggt cattttttat atcctttctc
    27421 atatttttta ttttttataa atttattttt ataattttta attttgtcaa atattaatta
    27481 ttgtcatttt tcgtaatctt attagcttac tgaactattc tatcattaat tatagtagtt
    27541 ttctactaaa ttaagcgact ttttaactct ctaatacagc ttttacttca tctttcgatg
    27601 ataactttaa taattctaaa aatctctctt catctataac tttaattcct aaatcatttg
    27661 ctttagtaag tttagaacca gcttcttcac ctgccaaaac aaatgttgtc gatttactaa
    27721 cactagatgt agcttttcca cctctttttt ctatcatatc ttttgcatca tttcttttta
    27781 atgtaggaag tgtaccagtc aatacgattt tcatcccttc aaatattttt tctacttttt
    27841 cacctgtatt atccaatgat tttgtattta ctcctacatt ttttaacttg tttataacgt
    27901 tcatattttt gtcttcctta aaaaactcga caacgctgtt tgccattata cttccaaatt
    27961 cctctaattc ttctagttgc tcactagttg cagaaattac ttcatctaaa tccttaaagt
    28021 tatatgcaag tatcttagct gctttaactc ctataaattt aatacctaat ccatttataa
    28081 gtctccataa atcattttct tttgattttt caattgaatt tattaaattg tcagcagatt
    28141 tttcgcccat tctctctagg tcgactacat cttccttttt tatataatat aaatcagata
    28201 catcttgaat aattttttca tttaatagca gtgtaattat agattctccc aatccatcta
    28261 tattcattgc atcccttgac acaaagtgta taattcccct tcttatttgg gctgggcaag
    28321 acatattgat acattttaca gcagcctctc cttctaatct tattgttggc tctgaacaaa
    28381 ctggacactt ttctggcatt ttaaaatcta tttcatctcc agtacgttct tcttttataa
    28441 cttctaaaac ttgaggtatt atgtcccctg ctttttgaac taatactgta tcatttattt
    28501 ttatatcttt ttctcttata taatcttcat tgtgaagtgt agctctactt acagtagtac
    28561 ctgcaagtct gactggttca agaattgctg aaggtgttat tgtaccagtt ctcccaactt
    28621 ctactattat atctactatt ttagttttct tcttttctgc tgggaattta tatgcaattg
    28681 cccatctagg acttttggct gtatatccca tttcgtctct ttgttttata ttgtttactt
    28741 ttattaccat accatctatt tcgtagtcta aattacccct gttatctgtc cagtattcaa
    28801 tatgctcaat aacttcatct atacttttac aaactttata actctgactt actgaaaatc
    28861 ctagtttttc taagtactct agtgattcac tgtgactttc taaatcgtat tcttctatat
    28921 tttccatatt aaatacaaat atatctaatg gtctctttgc tgttagtttt gggtctaatt
    28981 gtctcaatga accagctgca agattccttg gattagcaaa taatggctgt tcttgttctt
    29041 cttgttgttc atttactttt ctaaaattat cttttgatat atatacttct cctctaacta
    29101 ttagttcttt tttatcattt atcttaagag gtatgctttt tactgtcatt aagttttgag
    29161 aaatatcttc tcctacaact ccatctcctc tagttgctcc tttttcaaac tctccattgt
    29221 tataagttag acctacagaa agaccatcta ttttaaattc aacaacatat tcaacatttt
    29281 ctcccacata ttcttgaact ctcttatcaa aatctctcaa atcttgctct gaaaaagcat
    29341 ttgataaact caacatagga gttttatgta caatttgatt gaacttatct aatggcttac
    29401 ctcctaccct atttgttgga gaatcaattc tctttagttc tggatgttct tcttctaaag
    29461 aaattaactc cttcattaac ttatcgtatt cataatctga tatttctggg ctatcttgat
    29521 tataatacct ttcattatgg tagtttattg tctctataag tttattaatt tcatctttta
    29581 cgctcacttt ttgcacctct tcatattttt aaaattaaat tattttgaaa tttccctata
    29641 attaattatc tcctatttat atatttttta gtatatcact tttttggctt taaatttatt
    29701 acaaaaaaaa ctcttattag tatctttaat acgactaata agagttttta tttttatcaa
    29761 aattttttat ttttaatagc ctcttgatat gtctacaaca ttatctacag gtttattctc
    29821 cattatatag tgtttcaaat tattataaac catattaaat gttctctctt tgtttttatc
    29881 tgacacccaa gaattatgag gagttactat gacattttcg cactcccaca acttattgtc
    29941 cttgtttaaa ggttcacttt caaatacgtc taatgctacc cctctaaatt tctctacaca
    30001 ttcttctaaa tctttctgat taactgtatt tcctctacct acatttataa atacagaacc
    30061 atctttcata agtttaaaca tatctttgtt tactattcca tctgtacttt ttgtagaagg
    30121 cattgctaca actactatat cacattcttc aaatacaata ttcatatcct cagtagcaaa
    30181 acacttatca aagtattttt tactacttcc atcagtattg acaccccata tttctacacc
    30241 aaaagctttt aatctttttg ctgcttctga agatatagta cctgttccta aaaatccaac
    30301 tctttgtcca tacaattctg atacagaaaa atccatcttc cattctttat tttgttgttg
    30361 tttaaaaaat tttgcactat ttttatatat ttctaaaata tacaatacaa tactttcacc
    30421 aataggtaca ctatatccgc ctctattatt agctatctta atatttctct tcaatacctc
    30481 ttcttttgga agttggtcta tacctacact agttgtctgt atatattgta aatttttcat
    30541 cttagaaata tctaatctct caaatggatt gtatgtaact agtacatctg ctgtatttac
    30601 atcctcatta ttttcaatac tatcttcaga gtaatgtatg acatcatagc ctaattctct
    30661 tattttatca aatttttctt ttccataatt tattgtaaat aaaactttca tctcaaatct
    30721 cctccatcta cccacattta aaattttata ttctaaaata taatatgata ctcaatgtac
    30781 attagttaaa attactataa gatatcttaa atttacttat gttcaattgt ttttcctaaa
    30841 gacatagcat tacgttcttg aactaaattt tctattaaat tattcaatgt ccaatcaata
    30901 gatgtctctg ttaccatagc tgtaaaaggt ctatttattc tcactttttt tagcccttct
    30961 aaaaatgtat ttacttgtgt gcttggagtg ttattaaata ttacagactt actcttaatc
    31021 ccattttcac attcatttga tatatttcca tctaaaatgt ctcttattat attctctcca
    31081 tttttatcac ttaagatgat atggtctctt attccagcaa agttacttac gtttttaatt
    31141 aatgataatt cttttttatt aaagtttaca agcataatac acttcctgtt gtgtatttta
    31201 tctaggttat tattatttat tttttcaaat gacattttat ccatcctttc atttatttat
    31261 atactttaat ttaccccata catttaaaat aatcaatttt tatagttaat ttttatatta
    31321 atacccaaat tatatttaaa tagttaggct atccaaaact aatatataaa attagaataa
    31381 ttagattaat atctacaaat cataacctaa aggagagata ccatgaatac attactaaac
    31441 aataaattta gcattaaaaa cttttcaaat gcttgggtta tagtacttgg ttgtatgttg
    31501 atacaagctg ttccatttag tattgtagca agtatacagc ctcaatttat aagttatgtt
    31561 gtagaaggag aaggctttag tttagcttct ttttctctaa tattcactat tggtactatt
    31621 gcctcagcaa ttgcatcacc ttttataggt gtattatttt ctaaagtcaa tattaagata
    31681 ctatatttat taggttgtat aatttctagt attgcttttg ctactttttc tatatgtact
    31741 gaactatggc aattttacac tgtatcatgt attgttcaaa ttggcgctac aattatatct
    31801 gctataggaa tacctgtttt aataagtgct tggtttgatg aagaaagcaa aggaaaagct
    31861 ttgggctttg cttttgctgg tggttctatt ggtagtatat ttctacaacc acttgcagtt
    31921 cgcttattag caactcaagg atacagtcgt tcttatctaa tatttggaat tatagcatta
    31981 atagttggta tacctgtaat attattcata ctcaggatgc ctaaagatat taatgaaaag
    32041 gtaaaatcta aaggtaaaaa agagaaagca tctgatacaa tttctccttc agtatggggt
    32101 tatacattaa aagaagctaa aaaaattaaa tatttttgga ttatgactat tggatttata
    32161 tttgttggta tatatgtttc atcattgtcc gtacaatatc caacttatct tagaaattat
    32221 ctaaatccta ttctaatagg aacagtaggc tccacatttg ctttatttgc tctcattggt
    32281 aatttatttg gaggattatt gtttgataaa ttcggtcaaa caaagccact tattatatct
    32341 tttgtattgg ttcttatagc aactttatca ttactattgg tagataaatc ttctactttt
    32401 gcatttgtat ttgccatttt gaaaggtctt tctgtatttg cttatatgat tggtcctgct
    32461 tatttaactg gctctttctt tggtcaaaag gagtttggta gcatatatgg aatcgtacaa
    32521 ttaatttttg cagtgggatt tgcattaggt tcaacattat ttggattgtt agttgataat
    32581 tttggataca gattttcttg gtctattata attttatcag ttataattgc ctatacttta
    32641 cttattataa cttctatagg aatgaaaaaa ttgaataaag aaagattaga taaactaatg
    32701 caataattga tttttagata tataaatatt ataataaaaa agatggagct tttaatcata
    32761 aataaaactc catctttttt atattacaat atagctaatt ttctcttatt tttaacttta
    32821 ctatctatat cctcatcctt aactatagta aatgccttag ttggacaaac atttacacat
    32881 gcaggccctt ctggcgattc tatacaaaaa tcacacttat ttgctgtcat tctttctcta
    32941 aagcaaagct ttccttcatc tacatctttt aatgtaacta tgtctattgc acctatagga
    33001 catgctaaca tacaagtctt acatcctata caattttctt catttatttt tattgtgtta
    33061 ccaaccctaa ctataccacc atttggacat gcctttgcac aaggagcatc ttcacaatgt
    33121 ctacactgta ttggagcact tacttctttt gtctttatga cagaaagttt tggattaaaa
    33181 tttatttcat ctggattttg gtaaaaaata tcttcatctg aatgtgcaac tacacatcct
    33241 atcatacaag ttctacatcc tatgcattta tcagggtctg ctataacaaa atagttcatc
    33301 acttagccac ttcctttcct atacaatatg tagtgtgtaa tagatgatga gatttttctc
    33361 ctaatggttc taccagatat tcatcataca gttttttaat atcaggattc tcatgagatt
    33421 ttctaattgc taaatgttca tcatgcacgt atgttgcttt tgttctattt tcataagcca
    33481 attccttata ttcttctagt aaaatttttg gttgacctcc accacttaca cacccaacag
    33541 gacaagtcat aacttcaata aaatctacat ctaattttcc tttttccaag tcttcaagca
    33601 ctggtattac attttttaat ccacttacta ctccaactct taagtctaag tctcctattt
    33661 taatagttga ctttctaaaa ccattttctc ctcttacttg ttttacttct acatcaggaa
    33721 tactttctcc agttataagc tcatatcctg ttcttatagc agcttccata accccaccag
    33781 taacaccaaa gatagttcca gctccactat aactacctaa aggactatca aatttttctt
    33841 ctcttaaatt tttaaaatca attcccatgt cttttattaa ataagctagt tctctagtag
    33901 ttaatactac atctacatct ctatatccac tagaatccat ttcttctcta tcacattcat
    33961 attttttaca tgtacatggc attatagaaa cactaaatat ctttgatgca tctacattat
    34021 ttatctctgc accataagtt ttaaatattg caccacccat ctgctgaggt gatttacaag
    34081 aagataaatg attagttaat ttaggataat ttttttccat gaattttacc caagctggac
    34141 aacaagatgt aaacattgga agagttccac cttctgtcac tcttttaatt aattcactac
    34201 cttcttccat tatagttaaa tctgctgcaa aattagtatc gtagactcta tcaaaattta
    34261 aagctctaag tgctgctgcc attttcccag cacctaagta tcctaaataa tatccaaaat
    34321 cttctcctaa agcaactcta actgctggtg cacattggac catagtgaat acatttgggt
    34381 cacttaaagc tttcttcacc ttatctatat cacatacatt gtatgctgca aatataggtt
    34441 catttataga ctctggtatc tctctttctt gttttttctc ttgtaaaaac tcaaatcctt
    34501 catctataac tgaggcataa gatttacaag tttgaacaca ttgaccgcac ataacacatc
    34561 tatctaaatt tatctcttgt ggctttccct cttcaccttc aatagcattt actggacaga
    34621 cctttgaaca ttctctacat ccagtacata aatccttatc tatatttatt atcataaacg
    34681 tcacctaccc ctgtatcctt tatttatttg ttaacaataa actaagtgca gcttgtctat
    34741 tcttagcttt tttgtcatct attggagtaa caagttttaa tgcttcctga ggacatgcac
    34801 ttatacaagc tattttttca ttgtctttac ataagtcaca tttataagct atcttcttat
    34861 tttcatctaa aattacttgt tctacttctt taccatcttc atattgtgga agtaagtcta
    34921 tagctccaaa aggacatgct agcagacaag ttttacatcc tatacacttt tcttcattta
    34981 cagacataat attgttttct ttaactatag ctttttgtgg acatgagttt aaacaaggag
    35041 catcttcaca atgtctacac tgtattggca tacagaaatt gtcacctttt actaagtaaa
    35101 gtctaggtat aacaggtata tcaactgttc caactgtata acccacatta ttatgctgat
    35161 tatgcattgt aaaacaagct acttcacaag ctctacaacc tgtacatttg tttgggtctg
    35221 ctattacaaa agagcctatt ttatttttca tattatccca cctttcaatt tgtatatttc
    35281 caaccctcta gttattttca tcatatgtct acttactttc atcatatata tttatatatt
    35341 tcactatttt ctcagtactt atatttcgtt tacatttttt gcacaaattg tatgtgttat
    35401 tatatacctt atcagtatca tcaattaata ctccacagat ttcacacttt gaatatcttt
    35461 gctcttcttt tttagtacac atatattcat tctcactttt tgataactct ctgtggattt
    35521 gcataaatat tcatccgtct tcctcttaca aatccaataa gcgttatatt taatttttta
    35581 gaaagctcta ttgataaatt agtcggtgct gattttgata ctacaatagg aatttgagtc
    35641 atagctactt ttaatatcat ttccaatgat attcttccac ttacagccac aattttatct
    35701 tttaatgtta tgtcatttaa aacacaaaat ccaatagcct tatccattgc attatgcctt
    35761 gctacatctt cacaagtgac tattttttta tcaaaattaa atacagatac gctatgtacc
    35821 ccaccagtat ttttaaataa ttctgatgaa tttaaatttt tatccattat actgtaaatc
    35881 gtatcataat ttatttttat attgctcttt acaggagcac atgttatata gtctagtgaa
    35941 tttaaaaata taatttgctc atcttgattt ttttgtttct cttgaatagt tacttttgca
    36001 aaacgttcac tctcatttat ctcaaatttt aataagcttt ttttgttttc tatgtatcct
    36061 tttgttttca agaatcctac tataagttcc tctaaattat atggggtaca taaaaatgta
    36121 tttacatatt tatcatttaa aataaaacta agtggatatt ctgcaactat ttcttcatta
    36181 tctattgata cttcatgttc atttattttg cttacttcta cattaaaaga atttaaatat
    36241 ttgtagtcca ctagactata actattttca aaaactttat ccttactatt ttcttgtaat
    36301 ttagtttttg agtatatatt gttcataaaa tattagcctt tctgcctttt ataaatctta
    36361 aatctaataa atcattagat atttgtagct gtcattttgt ctttcaaact ttgatactct
    36421 tctcttacac atttttctgc taattcttgg tcttcaagtt tttcaagttt aacagcacaa
    36481 tatttatact ctggtgtttt agatataggg tctaaatttg ctattgtaag ttcattgcaa
    36541 gctccaaccc accactgata agtcatatat gttgcacctt ccttaactct atcagtaact
    36601 gttgctcttg ttattacact tcctcttctt gaactaattc taactaattc atcatcttca
    36661 attcctaatt tttcagcatc attagaattt atttgaacac gtcctggttc atcttctagt
    36721 gaactaagtg ttctacaatt accagtcatt gttcttactg aatagtgtcc aacttctctt
    36781 acagtacata aactaaatgg gtattcatca tcttcaactt ccataggggg tctccattca
    36841 gcagcgaaca aattaccttt accattagga gtagaaaact tttgaccttc atacagatac
    36901 atagttcctt tatcttccat actttcactc ttacaaggcc attgaacgca tccttgagtt
    36961 tctatctttt cataagtagc acctaagaaa cttggacata attgtctaag ttcgtcccat
    37021 atttccttag tatttttata attcatagga tatcccattg ctgtagaaat ttcgcttata
    37081 atttgccagt ctggttttac atctccttgt ggctctatag cttttctcat caattggaat
    37141 cctctatctg cacatgtata tactccctca tgttctcccc aagaagtagc tggaagtata
    37201 acatcagcat gaagtgctgt cttattcata aatatatctt gaacaatgac aaattccaat
    37261 tcatctaatg cttctctaac ttctgatgca tctgggtcac tttgcactgg gtcttctcca
    37321 aatatataat aagctttaag ctttttctct tttagtacta aatttggaac ttgagttaaa
    37381 ctataaccat tattaggaga taatcttacc ccccaagctt tttcaaactt ttctcttatc
    37441 ttatcatcag ttacattttg atagccagga tatacattag gaagagctcc catatcacaa
    37501 gctccttgaa cattattttg tccacgtaca ggtcctattc caacgctttc tctaccaaaa
    37561 ttacctgtaa gtagagcaat tgatgcaagt cccttaacta catcaacagc ttgaccaaat
    37621 tgacagacac ccattccata aagtatcata gcttttttac cttttgcata ttctctcata
    37681 gcttttctta taagctcttc tgggattcct gtaatctttt cagcatattt agctgtatat
    37741 ggtttaacaa tttctttata ctcatcaaat ccttgtgtat gattttgaac aaattcttta
    37801 ttgtaaagac cttcttctat taatacattt ccaaaagcat ttactaaaac catgtttgtt
    37861 ccacctttta taggtagatg tatatcagca attcttgcag attcagttac tctagggtca
    37921 gtaacaatta atttagcacc atttttttta gcttttacta ttctatttgc cactattgga
    37981 tgtgaatctg ctccattata tccaaatata aataaaacat ctgcattttc tatctctggt
    38041 atagaattag acattgcacc actacctaat gagtaagcca gaccggctac agatggtgca
    38101 tgtcagacac gagcacaatg gtcaacatta ttagttccta ttgtagctct cataaatttt
    38161 tgcattatat agtttgcttc attaccaggt cctcttgcag aacctgttcc cataatagaa
    38221 tcaggtccat atttttcttt aatttcattt agtcttgaag ctgtatagtt tatagcctca
    38281 tcccattcaa cctcttctag tacaccttgt tttcttatca ttggcttttt tagcctaggt
    38341 gttagaattt tagggtcatt tagaaaatcc catccataac gaccttttaa acacaaactt
    38401 tcttgatttg ttctaccatt agccggttca gctcttaata tcttattatc ttttactact
    38461 agatataatt ggcatccagc tccacagtat ggacaaactg ttaaaatttt tttctccata
    38521 caattccccc cttagattta tcccctgata agtaaaattt atcttaaaga taatgagtgt
    38581 ttttataata tgcaaaatca taaatatttt gcaatactat ctattaaatt caacaatttt
    38641 ctcacaattc ctcttaaatt tcaaaaaaaa tatgtcataa taatctttat atttcaacca
    38701 tttaattaaa atattctagt tcttatgaca tattttttaa tatactcaat atatattctt
    38761 taaacttatt tagttttcac ttaaaacaat atttctgcca attctatttt tcattctata
    38821 gtgagtaatt acagtaaata ttccacttcc aatcagaatc aaatagtaca taaatccacc
    38881 atataaaaat actgcatatc ccatcaaagg ttgagggaat actgatttga atatagtgaa
    38941 aaaggctaat tcattagctc ctacattccc aggtgttggt attggagata ttgccatata
    39001 taaaaatgct tgtaatgtca gtatataaat atagctataa ccttgtaaat taaatgcttt
    39061 atatatccaa aatgaaacac taaagtaagc acttaattga ataaaagtta ctattatagt
    39121 tgaaattaat acctttttat tctttgcaaa aaaatttatt gctttactat aatcatctat
    39181 aaaactttct atggattcaa tcttattatc taaaaatttt aaaaacttaa tttttgataa
    39241 atgctttata gtaattctca taaaatattt tattttttta ggatttaaaa taactaatat
    39301 tatcataatt aagacaaatg aattaatggc tatccctaga aacactagag gcataatcat
    39361 tttcatttgt ttttctaaca tagcaaaatt cattaaaaca agtattgtac aataaaaagt
    39421 aactactatt tggaagataa tagacttatt ggtaacaact gcacttgcct tactaagtgg
    39481 cattttacat tttttaagta catatatctg tactggttgg cttcctgaag caaaaggagt
    39541 tattaaatta taataaaatc ccataatggc tagcttaaaa ccaataaatc taatattaac
    39601 tttgtgagtg ctttctataa ttatcttcat tactactcct tcaagcatta tgtgacacat
    39661 tattgccaaa gcacctatga ataaaaactt cttatctacc ataaccataa catttgatag
    39721 cattttaata tccaatgttt taaacactag gtaaattgtt atacctatta acaaaaataa
    39781 aaatgtatac tgtagtaaac tctttctaat attctttagt ctatccatta gaaataacca
    39841 tcctttgctc aagatttata ctaaatacta tattattagt atacactatg aatcttaata
    39901 ttttataaca aaatacctta caattttgtc atttacaaaa aatattaatc tataaattaa
    39961 attttaatat atagattaat attttacaaa cattttgtag atatatataa tattttcact
    40021 aagcaacact tatacttatt acacccattt ataccctatc ccccatacag tttctattgt
    40081 ataaatatca tattgtttta atttgcttcg tatatttttt atatgctctg tgatagtact
    40141 tatatcactt tctccatcaa aaccatatac cgactcatat attctttctt ttgaaaatac
    40201 ttgtccctta ttttttgcta gaaattcaca tattagatat tcacttttag taaaattaat
    40261 ttttttacca tcaattgaaa cttctttgcc taaaaagtta aattgaacat ttgagatagt
    40321 taataaattc tttttttctc tactttctcg ccttaaatga gcagttatcc tagcccttaa
    40381 ttctcctaca ccaaaaggtt tggttatata gtcatctgca cctataccaa gaccgtacat
    40441 aatatcactt tccatatttt ttgctgtcaa aaacagtatt ggacaatcaa ccttatttct
    40501 tatagtttta catacttcaa aaccatccat cttaggcatc ataacatcta atattattag
    40561 attaaaataa ttaaaatcca tgttcatagc cttttctaca tcactaatta cctttacttc
    40621 atgtccatct cttttcaaca cattttcaat caactttaac atatctaact catcatctac
    40681 tactaatatc ttagacataa taactcctcc atttatccat ctaatagcat tctaatttat
    40741 atatttaata atatctttaa aattcacatt aaccataata ctctcatatt atagcttaca
    40801 ataattaatt actattttac aaataaaata ttttagatac aaaaacttta tatttcaaaa
    40861 actttatatt cattttacac gtatttactt aaatataaaa atttatttaa caatttatta
    40921 ttgtaatatt ttgaatatat aataaaatta ataataagaa aactttttat aaatatactt
    40981 ttaattgttt aaattggagg aaaaaattat ggatgaaaag ataacaaaaa ataattataa
    41041 tgttccattt gactatgttc gaaaaaaact caaagaatta gaccctcata caattagtaa
    41101 tttaagtaat atacctttca ataatggttt aaatagattc acactcaatt tttttgatag
    41161 acaatatatt atagactatc caagtggaga agtttggaat agtaatggta gcctttgcaa
    41221 taactttgag cttaaaatct tgatagttag atatttaatc aatgctaaag gtatccctag
    41281 aactaataaa tatgtaactt ttaaagaaat accaggaggc aatgtttatt atccaaattt
    41341 tttaaacagg actctatcta ggctttcaga agtttttaca tctcaaatag acaaatataa
    41401 gttagttatg gagaaaattg gagctgaaaa agtaaacatg ggagatttag cttataggtt
    41461 tacatatatg ggtaatacat ctatggtatt tatactttgg tttggagatg atgaatttcc
    41521 tccaaattca aatatattat ttgattctaa tatagtttat tacttcaatg cagaagattt
    41581 agcagttgtt cctgatacag ccataaatgc aattttaaat aaaataaatc aattataaat
    41641 ataaataata ttataataaa gtttttgata gatttaatag aatataatat gaaatggggt
    41701 aaaaaatgaa tgtagaaaat caatctttat cagatattga aataatatta tcacacaggt
    41761 atgataatgg tgcagactat tggactacac ctgataagcg tttaataaaa ggttctcctt
    41821 tctctactct tgatagtgta ctttatctat tagagttagg tgtgaaccct gatgatactt
    41881 tacttaaaga atgtgctgac ctgatattta gcacatggcg agaagatgga cgtttcaaac
    41941 tacatccaaa tggaggtatt tacccttgtc atactgcaaa tgctgctaac gtactctgtc
    42001 atatgggata tgcatctgac attagaatgc aaaaaacgtt tcaacatttt ttagatacac
    42061 agtatactga tggtgggtgg cgttgcaata aatttagttt tggtcgaggt ccagaaactg
    42121 aatactcaaa tccactacca actcttaata tattaaatgc attccgtttt agtaattatc
    42181 taaataaaga atcaaaactt gacaaagctg tagattttct acttgaccat tggactatta
    42241 aaaaaccaat cggcccttgt cactatggaa ttggcacatt atttatgcaa gttgaatatc
    42301 ctttccgtaa ttataaccta ttcctttatg tctacgtttt atcattttat aatcgtgcaa
    42361 aaaaggataa tagattttta gaagcattga agatacttga atctaaaatg ataggtaata
    42421 aaattgtcgt tgaacgtgta gttccaaaac tatccaaatt atctttttgt aaaaaaggcg
    42481 agtcaagtga aatagccaca acacactatt acgaaatatt aaaaaaccta gaaaaataat
    42541 agttatatag ataaaacata ttaaaaaata gtggctttaa attttttaaa gtcactattc
    42601 tatataaata taacaatata aaaaatatat taaactattt actctttttt aaaaccgttg
    42661 attttcttgc tatataaaaa actattatta tagaaataac tactagagaa cctctattta
    42721 taaagaaata attctttaat tcattaaatc taacatctat attgttaggc atataaaaca
    42781 tcttttgaat ataaaatcca tttacattaa tcatactaac aaatgggtac atatgtaaaa
    42841 taaaaaatat atcagcaaat gtatatgtaa ttaatattgc tattgttgta aatctatttt
    42901 ttgttaatgt taatatcatt agtggaaatg ttgtatacca taataatgta ggaaacgtct
    42961 ttaaaaacac atctattggc tttacactat aaacaaaatc tattttgtct atgttaaaac
    43021 ctttcactga cgtaaatgta tatactattg taattgaaat taataataat acagtatata
    43081 tagctaatat aacacaccat ctaaatacta taaattgatt atattttttt ttattatata
    43141 aagtaagtat ctcatttata ttacccgaat aatcttttga aaacacataa attattgtga
    43201 ttgctgacat tattggtata aaaacatctg atatctttat aattcctaac catcctgcta
    43261 tagaatatgt atccattata ggtacatcat tataaaatat taactcatta taatctaata
    43321 tgcctgtaat aaatatgcat aatatagaaa taattacaaa tattaacaca tgtttaagct
    43381 ctattttttt aagctcaaat tttattaact ccaatataca catttatttt aactccttat
    43441 gtaaaaagtt tatataagca tcttgtaaag ttgtatctat ccttaagcta tctttaagtt
    43501 tctctgtatt tttacctata tactttactt gcacaccatc tttaactctc ctataatcaa
    43561 taatatcaat attacgttct aaatattcaa attcatcatt agaaactact accgaataca
    43621 cctcaaccat atcaataaac ttattaattg taccatcata taatattttg ccttgattta
    43681 atataattaa tttgtcacag ttaaattgta tgtcttctac tatgtgagtt gaaattaata
    43741 ctatagaatt tttacttatt tctggtaaca atcttctaaa ttcattcctt tgctctggat
    43801 caagaccaac tgtaggttcg tccataacta ttaacttaga atcacctatt aaagcctgtg
    43861 ctatacctag tcgtctcttt acaccacctg agtatgtacc tattttttta tttataaact
    43921 tgtccagatt aacttttgat actacttttt gtatatgttt ctttaaatca ttcttagata
    43981 cacctctcat tttagctaca aattctaagt attcttgccc atttatatta ttatacatat
    44041 caaaatcttg aggtacatat cctacatttg ccttgatttt ctcattgttt ttgctatact
    44101 ttatattatt taattctatc tctccaattg aagtttcata aagagtcact aataacctca
    44161 ttaatgttga ttttccagca ccattaggac ctaataatgc aactactcca tctgttaggg
    44221 ttaaatttat attatccaga gcttttttat ttttgtaatt aaaatttaga tttcttattt
    44281 ctaacttgtt tatcatatta acctccttta ttatttatct attataagga tatttcctga
    44341 aagccaatga taaatagtta tgctaatttt ctctcccttt gagtcttcat ataaaaattc
    44401 attgctaggt aagtcagcaa ctaatatcat attaattttt tttcttttta ttgattccat
    44461 aacattatct acttcatcta catatttttt agcatctaca gatgctttgc tatcacctaa
    44521 tatttcattt cttgtttcaa ttaaaaattt aattttttcc tctatatcca tatttacatt
    44581 actatctgat ggatagatta tttttatatc atcttttacc tcttctttaa actcacctgc
    44641 atatattgca atatcatttg actttccttc aaatatataa tcttttttta aaaaattact
    44701 agtcttattc agtaaaggta aatttgaata gacattattt ttagaactta aatttatttt
    44761 ataagccata caacttgatt gatttacttt tgggtaccac gctaaagaac ctggtggaag
    44821 cataatatca tctttagtag ctatatattt attttgattc caagatgtca acacattaat
    44881 atagccttca tactctatat ctaatgtcac ctcgtcatta ggctctaaac tttcctttaa
    44941 attaacttca attaaatcct tttttttgtt aaattttata ttttccgaat ttacttttat
    45001 atattttata tcaaatattt catctaaaat catattaata tttgttaact cttcatttga
    45061 tgtgtttaat aaaacaattc tatcttttat atttgacttg cttttaaagt caatcttcat
    45121 atcatgcgat tttattttaa tatcactaat attagatttc tttaaatact ctccataact
    45181 acgctcctca tctctatatg ttgacatatc tattgatata taatttaatc caataaataa
    45241 aatactgtac actactataa ctattaatga tttaatctgt ttctttctaa tatcatttaa
    45301 tatcagatat gctactatta ttaaagtaat tgcaaatagt gtaggtataa tcttatctat
    45361 aacatatgct gaattattaa ctttccctac aaaatcagaa tagtaagcat atgattgatc
    45421 ttcaaatatg ttaagtgatt taaataatgc tttaaaaaat ggttctttaa tatcaataac
    45481 tctatccaac atcttagttg atgttaaata taaaaatact gatgataagg taatctttag
    45541 tattaaatta tttataataa ctgaaataaa tgatatcact atagataaaa tagtaagtgg
    45601 taaaaaccat tcaaatatca atataaatat agttgattta atcgttacaa ttgacaatgt
    45661 tcttattaaa cttgagtatg ctatagcata tataattggt atgcaacaaa atataaagtt
    45721 gtttctagtt acagcaacag aaatacctaa aaaataatca aaattatttc tacataatat
    45781 ttttacagta tcataacttt ttctcatata aaaaattaca tttaacatgg ttaaaatact
    45841 aattgtcata caagtatata cactcaagga taagtaatca ttaaatgaaa ttcctctatt
    45901 ggatatatgt gtccatcgtt gtatgagatg gtaatttata ataataactg ttattgcaaa
    45961 taaaatattt tttctaatta ttttggttat aaagtctgat ataaccttaa tactactcat
    46021 atttatgccc ctcctagcca gtcttttgat acaacctaca atagattcaa ctatatttaa
    46081 taagttcaaa tacttacctt gacattattt ttttaaagtt aatattaatt agtgaagtta
    46141 attaatttag aaaatgtttt ataatcttac tgatcactat taaccttcat tccaatatat
    46201 attaatatag caatccaata tatagaaatt attgcataaa tcacatattg ctgaaaaata
    46261 ttaagtattt tacataaaat aattaaacat attattacga atagtatttt ttgcacagtc
    46321 tttctataat gctttttctc actttcacta agaggtttgt ttctatgttc taaaggagct
    46381 aacttgtaaa ttgttagtat actaataatc attaataata ctaataaata cttatattta
    46441 tttatatcta tattattagc tgaaaaaata gttatcaaat aaataactgc aaatgttaat
    46501 gtacactctt tataattcct agcatgataa cctcctgtga actgtcttaa agtgcaataa
    46561 caacttaaaa atataattgt atgtataaat ctatcaaaaa taattcctat aaataatgct
    46621 accaaaatat taactatgaa ataaatcaaa gtttcaaatc catatctata tatttcaaaa
    46681 tcttcacttt ctacaatctc attattaact aatatattgg caaatttata tgataatctt
    46741 ttaaacatat ttcctcctca acatgtaaaa cctctccttt aataagaaga ggtcctttta
    46801 ttaatgttat ttttttagtt tttgtaaagc ttgtggctct tttgcctgat gtgctaccca
    46861 agaacttgca ctgtttgctg ataatacagc tatcccaaaa cttaatgctg agatgttttt
    46921 aagtaagttt aacgctattt ttttcatttt gtactctcct aactttttat tggtatcatt
    46981 atttttaata taaactcatt atctgagtaa ttaactattg tttcaccacc atatttattt
    47041 actatatatt taatactagc aagtcctatt ccatgtatct tatcatcatc cttactagtt
    47101 tgaatacgtt tatcaataag tttaatatca tttaccttag tatttataaa ttttattatt
    47161 gcaaatttat ttatatatgt agctttaact tctattcttt tttctatctc attatttata
    47221 tccatacatg cttcaattgc attatctagt gaatttgcaa atattgaaca tatatcatta
    47281 tttttaataa agtttaattt agatatattt atgttatctt caatttgaat atcatacttt
    47341 ttacaaatac ttattttttc tgctaaaatt aaatctaatg ttttatttcc agtattttta
    47401 aaatgttcaa attcacttat ctgaaactct aagttattta tatatgatat aatttcttct
    47461 ttagtgtcat aattttttat acaaatcata tggtttttca agtcatgata aacatatttt
    47521 aatctatcat gaacttcgtt tatattttca taattcctgt agtttgtttt tattctttca
    47581 tttataagtt catactctag atttaattta tcgtcttgta caattttccc tattactatt
    47641 aaaagtatta tacttgatga taaaatcaat aaaattgcaa atataaatat aaataagttt
    47701 tctgtagtaa ttgtattgac tcttaaatta tattcaaata taagtaataa gctaactata
    47761 ttagataata taggtattcc tattagtatc atatctttag gtttaaaatc taaagataat
    47821 ttaaaatact taaacaatat aaaacctata aataaaaata cctttgacat aataatagct
    47881 tgtattctaa ataagttttc atgttgtgtt atgttaatat tatttaattt atttataaat
    47941 actactagac ctactgcaga accttcagca accattaatc ctagccaaaa caataaacta
    48001 actattatac ttttatagat tttatcttca tatgatgtta tataaaatga tattcctatt
    48061 accatacata gaagaatctt aatatttgga aacactttaa ctacatttat gtatgccata
    48121 aatataatta taattattgt tgtaaatata tatcttatat tagatatttt cctctttcca
    48181 actaagtgga ttactaaaaa aaatataatc caatctatag tacctgaaac taaattaata
    48241 atattccaaa atcctacact taaatttgtt agcatactat gtcccctaat atattagtta
    48301 tcgcaagctt caagccttta accctatatt tacttattgg aatacttttt ccatctacta
    48361 taacagtact tccactcatt gattctacta attttaagtt aactatatag ctattatgac
    48421 atctaaaaaa tccatattca tttaatatct tttctatttt agatatactc attttagtaa
    48481 tatacatatc atcatgtgta taaatcaata tattcggtct atctgtttct atataagtaa
    48541 tagaatctat tttaattcgg tctacataat tttttacatt tatagttaag taattatttc
    48601 tctttttcat catctcattt atacaaggta atacactttt agaaattttt tctttattta
    48661 ttggctttag tatatatctg tatgctttta cctcataacc ttcttgcata aactctacaa
    48721 atgaagtaac aaatattatt tctaacttat gatcaaactc tcttatcttc ctagcagtat
    48781 ccataccatt tattgttttc atttgtatgt ccataattaa tatgtctaaa tctttaggat
    48841 agttatttag taactcttct cctgctgaaa attcatatat gttataattt ataggatatg
    48901 aacttaatat ttcacttaat atatctttta tttttattcg ataatgtagt tcatcatcac
    48961 atattcctat attaatcaca attcttaaac atcctttctt atatattttt aataaaaata
    49021 tataaatttc tattcatttt acatatttta acatacttct gtagtaaata gctatttaga
    49081 ttttaatttt agctttttgg acattaagta ttactttttg gatttgcaat ctattttaat
    49141 tttcattata atacaatttt ttaatatata ttaaatatat ttaggaattt taataaaata
    49201 ttcctcgaaa agtttttaat atctagtttt tgttaaataa aaagtatgca ccttcctttt
    49261 tatagtaatg ttttaattat cgctataaat ttgaagaata cacactttat tttaaatact
    49321 catataaaac atattaaaaa atagtggctt taaatttttt aaagtcacta tttttttaaa
    49381 tgatgttact gaaaatatat taagttagtt attctaatca atttgaagac ttttgcttct
    49441 ccttgcctat atctaacata atttcataat ttaatttacc tttctttaaa tcaactcctg
    49501 agttacttct aataatccca caatccaaca tttcgtcaaa taccttccta gataaaccta
    49561 gtttctcacg taataatgtt gataccttta actgacatgg atatttacta ataatatgaa
    49621 cttgtgtaaa gtcattaata ttaatttctt gtcctactat tttatactct ggaataccaa
    49681 cttctgctcc atttctatgt aaaagttcca tattcatagc atattgctta acaagattat
    49741 aatcgtttgt atggaattgt tctagtattt ctggatttaa gctttttgga ttaacacgag
    49801 aatatatagt tgagttccat gttgaatcac aatttgaaca cttgtatatt aaccatatat
    49861 ccaaatattt atgttgagca ttaaccctaa ataaacctga acaaatatat tcagtctttt
    49921 ttccacattt tttacaatac ctaattacag gtaactggga gatatattcc acctcccaag
    49981 taattttttt cataaatgca atttcctttc tataagatta ctaaattaat agaaagttat
    50041 gaaaaggtgg aatataatca agtatttttt tcaaaacaag acctcctaat tttaataaat
    50101 tttaatttca aacatataaa aagctactac ttcttattag atactttaca accagctttg
    50161 ttagctactg tataagttgt tgaaattact taaattatat catccactta aaagaaacta
    50221 tacctcaaac acttttatca aaagaaaatg agccagtata attataaaac tatactggct
    50281 cattcttaac tatcttttct tttttcttgt aatacaattc tttgaatact tttcaaagac
    50341 aagtaatatt tttctgataa atatttcaaa tcatatccaa cttgataatc ttcataaatt
    50401 tgcatatttc taattgataa atcttcacga gtagacgtac tacttcccca ttctttttta
    50461 ttattagact ttctaggaat atagatatat tctccatcta catattcctg tatcaattca
    50521 agtaattctt ctggtaatat atgtattgct tttttatagc tcattctgca ctcctattaa
    50581 ataataattt tttattagga atagcaaagg gctatttata tattaaattt tatatttgca
    50641 atagcccttg ctatgcaaaa ataaagatta aatcaaacat aaatctcacc cctccttata
    50701 tatcacagcg atacatataa gtctatcaac agtataactg gttgtcaatc aacacaaatt
    50761 atttatccat tttttaaaca catttattta gtttttatat tatatttatt ttgataacta
    50821 aaattttttc attataaact atctttaaaa ttattagtca acttaaatcc attatcttga
    50881 tgggtttatt actgaacaag gaactccaac tatacacttt ccacaaatat cacatccacc
    50941 tatataagtg tatttttttt catttatcat acacatttca taacacttat tcctattaaa
    51001 tccatcttct tttaaagctt ctttcacgca tttgttgaca cattttttgc aactattatt
    51061 atgtttatac aagcagtatt cattttctgg tcttttagtt ggctctaatt ctaaacttgt
    51121 gattatgctt cctattcttc cacaacaccc tttttctgta ataagcatat tatttaaacc
    51181 aaaagttcca agacctgcta tgaatgctac atgtctttgt gaccagtcac ttaccaattt
    51241 ttcactgtca aaattatacg acccaggaat agcatatgaa ttagccccta tcttctctag
    51301 ttcttcacat aagaaatcat ttaaatttga aatcaacata ttagtttcta tgtacgctct
    51361 tgcccatatt tcagaacatt caaaccctcc aatattacta ttatttacac tttcatcaaa
    51421 aggtataaaa tatgtaatta tagtttttcc attttccaga aaatcttttg gcatagcatg
    51481 agatgttcct acaacacttt ttagcttctg aaacatatca tcttcagcag atgcataagc
    51541 aaacaaaagt tcttgccact ttgtagttat attatttgat ttatgataat tttttacaaa
    51601 gttgttcatt gatatttcaa tcttattttt catagtatca cccctagata attctatatt
    51661 tccaatttaa tgttattatt ttatattata taatagtatt ttataatatg cgcactaatt
    51721 aatattaaaa ctatgttcat caatcattct taaaaaagct cctaatatca atacgatatt
    51781 agaagccttt tcttatctaa tctaatttat tgcaattcct gcacttgcat atcctgctac
    51841 agtattaact aatgaaagac ctgaagctgt tgcagtaaat actagtaaga atcgagtttg
    51901 cgctgttgct gctatattta atcctgttac aattccacta gaaattgaac caactgataa
    51961 tatacctgta agtggtggag ctagtgtaac tgtcgctcct ggtacagctg taaatgagtt
    52021 atttggtgca gtagattggt aaagtgttgc tgtaattgta attgttgaac caacaagtga
    52081 aagtgctgct gttgtactga agtatgctga aatagatgtt attgttccat ctcttggcat
    52141 tgaaaatgca aagttagtca atgttcctgc tgcgtttgta aggtctatta ctccaccaac
    52201 tatacttaat cctggagctg aactaccaaa tccaacaaat ccaggtgtac ctactaatcc
    52261 tccagctata gttgtaagtg atagtggtat acctgatgca aaaggtatta ttgcactagc
    52321 acctgttggg cctgttggac ctgttgctcc ggttggacct gttgctccgg tcgctcctgt
    52381 tgctcctgtt ggacctacta acccatctgc ccctgttgga cctgttgctc cggttgcccc
    52441 tgttgctcca tctgctcctg ttggacctgt tgctcctatt gggcctgttg ctcctgttgc
    52501 tcctgctaat cctgttgctc ctgttgctcc tgttggacct actaatccgt ctgctcctgt
    52561 tggacctgtt gcccctgttg gacctgttgc tccatctgct cctgtatttc ctgttgcccc
    52621 tgttgctcct gttggacctg ctactccatc tgctcctgtt gctcccgtcg ctcctgttgg
    52681 acctactaat ccatctgctc ctgttggacc tgtcgctcct gttgctcctg ttgctcctgt
    52741 tattcctact cctgttgccc ctgttggacc tgttgggcct actaatccat ctgctcctgt
    52801 tgctcctgtt gctcctgttg gacctactaa tccatctgct cctgttggac ctgttgctcc
    52861 tgttgcccct gtcgctccgg ttgctccatc tgctcctgtt gctcctgttg ccccggttgg
    52921 tcctattaat cctgctgctc ctgttgctcc tgttactcct gttgggcctg ttgctccggt
    52981 tgctcccgtt gctccggttg gacctattaa ccctgttgct cctgttattc ctattcctgt
    53041 tgctccggtt ggacctgttg ggcctgtcac tccaaatcct gttgctcctg ttgcccctgt
    53101 tggacctgtt actccatctg ctcctgttgc ccctgttggg cctgttggac ctgttactcc
    53161 tgttgctccg tctgctcctg ttgctcctgt tgctcctgtt ggacctgtta ttcctattcc
    53221 tgttgctcct attgcccctg ttggacctgt tgctccaggt gttcctgtcg ctcctgttgg
    53281 acctattaat cctgttgctc ctgttactcc tactcctgtt gctcctgttg ggcctgttgg
    53341 acctgttact ccaaatcctg ttgctcctgt tgctcccgtt ggacctgtta ttccatctgc
    53401 tcctgttgct cccgttggac ctgttggacc tgttactcca tctgctcctg ttgctcctgt
    53461 cgctcctgtt gggcctgttg gacctgttac tccaaaccct atagctcctg tcgctcctgt
    53521 tgggcctgtt gcccctgttg ctcctgttgg acctcttaat cctgttgctc ctgtattccc
    53581 tgtatttcct gttgggccag tcggaccggt tggtcctgtt gggcctactc ctggacctgt
    53641 tggacccgtt ggacctgttg gaccggttct acctcttgga cccattgggc ctgttggacc
    53701 tacacatgat ggtggacagc aatgatggca atcacagcta ttataatcat cacgaccatt
    53761 gttacaatca tcatatttat catagccatt gttgtaatca ttatcatcaa atggtccaaa
    53821 atatttattt ctactcatta ttaaaagcac ctcctgatat atttgagctt ttaagctcta
    53881 tatataatat gtcaaattta gtatgattgt gacctatcaa ctatttttaa atttactaaa
    53941 ataattttca ttgtgcaaaa cagcactatc gttaggtttg atttcttttg ttttttcatg
    54001 ataataaata gctttatctg attctcctaa cctgtcataa cagacactta attgtataga
    54061 tggtatatat ccataacaat catttgactt aaaacctcca ttagtatcat tcttatctct
    54121 tgttaatgct accttatacc aaaaaatggc ttctttatat ttttgtctat caaacatatg
    54181 ctttcctatg tcacaacaaa tttctgctct tggctcatca aattcgaaac ttctaaacaa
    54241 tgaatataag gcactttttt catcattaat taagtaataa catgtggcta aatctctgca
    54301 agcactgata caatcctcaa tccatcctct tgatgagtct aaaaacttag taaaaccttc
    54361 tattgcttct ttatacctag cattatagta caactctcta gagtaataga attggtgtct
    54421 tggctccaat gtttttcctt ctgaaatcat tttttcaaaa attctaagat ttcttagagg
    54481 gtcctgtcta tgaagctttt tatgagatat tgcaatgtca gaataaaata cctctccaaa
    54541 aagaggtact acttcatgaa tagggtcaac ccatttatga ttagaacttc ttttaaacaa
    54601 tcgttctcta taatatgaga gagttgggtt accattttca tcaaaggata cattgtattt
    54661 tgccataaca atatcaatgg aagtatccaa gctttcttta atctttaata atttttctct
    54721 atcagcttct aaaattatgt catctgcatc aagccacata gtatagtctt tagaagcttt
    54781 agaaaatgaa aaatttcttg cagcagagaa atcatctatc cattcgaaat cgtacaccat
    54841 gtctgtatat tttgagacta tttcttttgt ggaatctgta gagccggtat ctacaattat
    54901 aatttcgtct actatatcct ttacacattc taagcatctg cctataactt cttcctcatt
    54961 cttaacaatc atgcacaaac ttattgtaat cataatgtac aactcctttg tcttctatat
    55021 attgcagaca taagtaatat atggtatttt ctcttgtttt gttattaaat ttataaaaac
    55081 ttttgacgac agaaagttac taaagaacct tatcttttat gtatttttta tagtagaatt
    55141 tattaaactt gaaatttggt aataattgtt gaaatgataa aaccatattt aatttcatac
    55201 aaaaaagagt gtcccataaa ttaaaaagtt cattttgaga cactcttatt taatattata
    55261 tatatacttg taaaacagac attttaatat gatactttga tactttattc attcctattc
    55321 attatataat caatcagccc gtactcttta gcctctagtg cagtcataaa attatctcta
    55381 tctgtatctc tcctaatatc ttctattgat ttacctgtat tttcagaaag aattttatct
    55441 aatcgttctt ttattttcaa tatattatct acagctattt ttacatctgt tgcttgacct
    55501 ttagctcctc ccattggctg atgaatcata atctctgaat taggtaaagc acatcttttt
    55561 ccatgtgttc ctcctgcaag taaaaaagca ctcatgcttg cagccatacc aatacaaata
    55621 gtcgatacat cacatctgac ataattcata gtatcatata tagcaaatcc tgatgtagca
    55681 gagccaccag ggctatttat atatataatt atatctgaat ctgggtcttc tgattctaaa
    55741 aacagtaatt gagctactac taaacttgca atagcatcat taatttcttc tcctataaat
    55801 ataattctat cttttaataa ttttgaatat atatcataag acctttcccc ttgacctgtt
    55861 tgttcaatta catgtggcac taaactcatg ctactttcac ctcacaatta atattaaagt
    55921 tcagataaga attgatttca tctcttcttt gtttataatt catatttgca taagaaatac
    55981 atttttcgct ttgaatttga tgatttagat ttaaaacaaa tctctgctga ataggataaa
    56041 attcatcttt atttctatat acttgtggag attctttata taaatttcta aatgctagtg
    56101 taaaagattg atgtgtagaa tatcctactg taatagctat gtctataata tatttgtctg
    56161 taaatataag ttgtctagct gcttcagtaa gtctcctcct ctgtatgtat tgatggatag
    56221 tacatcctac aacatttgta aacattctgt gtaaatggta ttttgaataa ttagcaatat
    56281 aagctatttt atctaaattt agattttctg taagattttc ttctatataa tcaattatct
    56341 ccataataac atctgtattt gttttcaact ctatcctctc cttttaagta ttataaccta
    56401 tgcaaaaagt tttttcttaa tataaattgc tatcttaatt tagtgtatag caataaagta
    56461 tcgataaaaa aatatcaggt atttttatac aaaaatatta atatatattt cttttaaagt
    56521 ttaaacttaa ttacatctat tatatgtaga ttgctacatg ttttatctat gtaccttgat
    56581 tcatatgtat tattttgctg agtattttta cacctttttc aatttcatca aaactaagat
    56641 gagcataacc tagtataatt tcatggtcat attctaatat attctcaatt gcatattgtt
    56701 gtataggata aacttttata cctgcttcaa aaattttatg aattaaactt tccgtaaatt
    56761 taacattata gaaatgagca actatatgaa gccctgctgc ttcacctttt attttaaatt
    56821 catttttaaa ttccgtgttt aaaactttta tgaggtactt acgttttcta ttgtacaact
    56881 tcttcattct aaatatgtac ttctctaaac ctccatttcc aataaattca gctaatacat
    56941 gttgcaatat tgtttctgta tgaacatcag agtacatttt taaggtttta tagctttcta
    57001 aaatattgtc tggtaataac ataaatccaa cacgaatagc tggagataat attttactaa
    57061 aagaacctat gtaaattact ttatttgggc taagttcata aagagaacta attggttgac
    57121 cctcatatct aaattcacta tcataatcat cttcaattat atagtaatca ttctctgttg
    57181 cacatttaat aagctctagt cttctttgaa taggtaaaat ccctcctaat gggtattgat
    57241 gagaaggtgt agtataaaca aaagaaatcc cctttattga ttttattaag ttggtattca
    57301 ttcccttatc atctacttta attccaacaa ctgaatatcc aatagatgaa ataaccttta
    57361 ataagccttt atgaataggg tcttctacag caaccttttt attacttttg tataaaagct
    57421 gtgaaattaa agataaacct tgtgttgaac cagaaacaat cataatgttt ttgggattac
    57481 atctaattcc tctagtacga aataaatact tagatatttc cactcttaaa acccatacac
    57541 cagctgtact tccatatctg aaatccgaat ctgataaatc atacagtatt tgtttatata
    57601 gctttgaaag ttctttgcgt ggaaatagtt ttaattctgg aactcctgaa cgaaaatcta
    57661 tataattttt ttgtttatta gtatgtaaat ctttttcatc tctaaaagta tcatttaact
    57721 taaaatcaac tttatgccct gatattcctt tagctacaat tgttccatat ccattccttg
    57781 tttccaaata tccttctgca attaattgat tatatgcatc taaaactgta ttacgagata
    57841 cagatagttc ttttgataaa gtcctagatg atggcagttt ttgctcaaac tttaagcttc
    57901 catccagaat catatctttt atctcacaat aaatttgtct tgataatgat atattactat
    57961 ttctattaat cgtaatccac attctaatac ctccaaaagt ggttctataa aattactata
    58021 aaaatggaac tacaaaatcc acttttaatt tgctaagatt atatcataaa atataaaata
    58081 aaaaggagtc tatattatgt tagaaatatc acataaagtt aaagaaattt atcccaatat
    58141 taaatttgga gttatggtta taaatattac acattcaaaa cctaataaag aaaatttttt
    58201 agttcttaaa aactctacaa ttaaaaatat tatagaacaa cacccagaat acaatcgtaa
    58261 agaaaaaatt aaaacagagc ctgtttcaag ttatataaag tattataaaa aattcaagaa
    58321 aacttatcct gtattgcttc aattagaatc tattctatta aaatcaaaag gtatcccaga
    58381 tgtaggtgta acaattgagt caatgttttt agcagaattg aaaaatcttc ttctaacagc
    58441 aggtcatgac cttgataaaa tggaattacc tttgaaaata gaattagcaa atggaagtga
    58501 acatttttat ggtataggtg gtaaagaaca tattttaaca aaagatgatt tatttttatc
    58561 agataatatt ggtatattat ctagtattct taatggccct gataatcgaa cagctataac
    58621 aaaagatact aaaaatatta tgtattttgt atatggacct gataaaatat cagaaaagca
    58681 aattcaagac catttaaatg atataaaaca ctatatttca agtgcttttc cagatttgaa
    58741 agttaattca attgatatat tttagttaat atattaaaat cctcataaat attttgaata
    58801 aataaattag tgaagtatac attctagtta aactagatat acttcactaa aattaattat
    58861 atgtagatat tatttatttt gaattttgtt tataataaac actttattac atttatccta
    58921 tgaataactt aattttataa ttaaagagtt tcataagaaa caatttcact taaaggaaca
    58981 cgagtttttt catgtctctc tgggctctct ggtatcttag attcatatcc catcaataat
    59041 atatttattg gttctagatt atctggcaaa ctaaactctt ctctaattat atctggatta
    59101 aaatagcaca cccaaacact tgccaatcca agttcagttg cctgtaacat catatggtct
    59161 gtaactatac ttgtgtcaat atctgtaagt tgtttcccat caaaaggtct tgtccaaact
    59221 ttgtctttat ctccacatac aagaattgct aatggcgcat catatatatt ggcagcctta
    59281 gaaagtttat ttataccttc tttttcctga ataacaatca atctttgagg ttgacgatta
    59341 ccaccagttg gagctattct tgcaacatct aaaaccttct caagtttttc tttttcaacc
    59401 tttctatctt gataattacg gcaagaatat cttttttttg caagttcaac gaaattcatt
    59461 tatttacctc ctattgtttt attaggctaa gttgatgatt tatttaacct atgctataat
    59521 tttatcacta tggtactata ttacaataat gcactttttt gtaatatagt acctaaaaag
    59581 atactttaaa ataaataaag gagcccaaaa atgaaaaaat gtttagataa ttacagttgc
    59641 ccaatagaag caacacttgc attgattggt ggtaaatata agacacttat actttggcat
    59701 cttaaagaca ctatattgag gttcaatgaa ttaaaaaaat taattcctaa agcaacgcct
    59761 aagatgttaa ctcaacaatt acgtgaatta gaatcagatg gtttaattat aagagtggtt
    59821 tatcctgttg ttcctccaaa agtagaatac tcgctatctg attttggaaa gagtattatt
    59881 ccaattttag attccatgtg tgactggggt tctgattact tagaaaatct ataaaccatt
    59941 acagtttaaa tcccattgct aatttaactt catccatttg ttctttagat gtcaacattt
    60001 ctaaaagctt aaaagctaca tgtggagctg tttctggaca atatgaggtt ataatatttt
    60061 tatctacaac aattggttca ttaactacat ttacatcaaa ctcacttaac tgtctttgtc
    60121 ttttaccatt tttcaaatga tatgtagtag ctttacgatt ttttaaaaca ccactttttc
    60181 caactggcaa tgctgccaca caaatagaag cgattatttt ttcttttgaa ttaaactccc
    60241 ttattagatt taaaaaagat gaatcatatg cttcatcata aaatccaaat tcttcaaatc
    60301 ctccaggaat agctagagca tcataatcat caacacatac ttcttctatc gtcttatcaa
    60361 ctaatacttg tatattaaat gtgctcataa cttgtttttt aaatccacaa gtcactacat
    60421 caatatcatg cccataatcg ttacgagccc atcccataac atctacaaat acactaaatt
    60481 ccatagtttc aaaacctttt gctaaaaaaa ctaaaacttt catattctat tttcctccta
    60541 aaatataatt aacactttac tagtaaatta tttaaaaaat atcttttatt gtattaaatt
    60601 cttctttaat tgtagataaa acaatggttg tattagcttt ttgaatcccc ccaatttcct
    60661 tcaaagtcac tgatataaac tcttcaagat tacttgtatc ttctgctaat acttttatta
    60721 agtaatcata ctctcctgaa atatgatgac attctaatac agtatcatat tccaatatag
    60781 ttttcttaaa ttctttcata cttttagata aatcagtatt gataaatata aaagccaaaa
    60841 gcttatattt tgttttttcc cgattaattt gaatagtgta cttttgaatt aaatttgact
    60901 gctcaatttt ccttatacgc tctgagactg ctggtactga taaattaatt tgtctgctta
    60961 tttcagaggt tgaagcccta ctattctttt ttagagaatt aattattttt aaatctattt
    61021 catccagagc tactcacctc cttaattatt taatacaatt ttagctaata atttacatta
    61081 agtaaataaa tttaatcatt tcaataaaat ttaatacaaa tatgttattt ttccttaaaa
    61141 ttttagtttt ctttaatcaa aacacatata atacttaaaa ttatttaagt tgaattaatg
    61201 tttttatttt gtataatata ttagaacctt aatatatcat tgaaaattca acaatactag
    61261 acatatactt ctacatgttg taatatttat gaaaatagta tccctatatc aaaattataa
    61321 aactcataat cttaattttc ttatagacta taaaatttta ttgatagcga gtcttcaaat
    61381 aactttgtaa tgatagattt actaaattaa tataataata gtaaatataa ctttcttatt
    61441 gactataact aagtattatg ataacataac ttaagctata attaataaaa catattttaa
    61501 atagataaga taatccacaa agtacaaaag tacaatttaa atatagataa actagaatta
    61561 atactaagat taggatgtga ataattatga tttatataga attagttaaa cttgttagaa
    61621 aacttaactc tacacaaatg tatacgatga agcgttgtgt agaggttaat ctgaaagctt
    61681 aaagctttct atcttcatcg gcaaatatag gtttagtata gttttttggc tatgcttatt
    61741 taaaattacc tatttgccga tagataatat agattttctg gtcatagaca acaatgcttg
    61801 tctatgacct tttgtttttc caaaagcaga ggtcggcatt ttacaatgcc attcctctgc
    61861 tttttttatt tccataaatt ttttaataaa agaaaaggag tttgaattat gagtttatta
    61921 aaagtaacta atttatcaca atgttttatg gataaatcac tgtatgagaa agctaacttt
    61981 gatttattca aaggtgaaca tataggtgta gttggccaaa atggtacagg taaaagtaca
    62041 ttaattaaaa ttttattggg agaagttgtt ccagattcag gagaaatcaa gtggcaacct
    62101 aatatcaata taggccattt agaccaatat gcagaaatca atagagatac aacaatatta
    62161 ctctatttac acactacatt tgaagaactt tataaaatag aaaaggaaat gaatctactc
    62221 tatcaaaaaa gtgctatatc tgaaaatgag caatatctaa tcaaagcatc agattatcag
    62281 gaacaactaa tagcaaataa tttctattct atagataatg aaataaataa aatagcaaat
    62341 ggtcttggat tagattcaat aggaatgaat cgtgttgtta gagagcttag tggtggtcaa
    62401 agggcaaagg taattttagc aaaattacta ctttctaacc atgatgttct attattagac
    62461 gaaccaacaa actttttaga taaagaacat gttgaatggc tctcaaatta tttaaataca
    62521 tttaatgggg catttatcgt agtttcccac gattttgact ttttagaaaa aatttctaca
    62581 ggtattcttg atatagaatt tggcatgatt aagaaatatc atggaaaata ttcagagttc
    62641 cttaaacaaa aatcacattt aagagaagat tatattagaa ggtatcaagc acaacaaaag
    62701 aaaatagaaa aagaagaaac atttatacgt aaaaataaag ctggagtaaa ttcaaaaatt
    62761 gcaagaggaa gacaaaaaca attggataaa atagaaagaa tagctcctcc tagttttata
    62821 ggaaaaccaa atattcaatt ttcagaaatt gaaatatcgg cccaaaatgc tcttactata
    62881 acaaatcttg aagttggata ctactattct ttacttccaa aattaaattt ttctgttgat
    62941 ggaggtcaaa aaatagttat aactggtttt aatggaatcg gtaaatctac cttgttaaag
    63001 acattagtca aagatattcc tcgtatatct ggaaatttcc agttttcaga acaagttaaa
    63061 attggttatt atgagcaaga tttaaaatgg gaaaatcctg ataaaacccc acttcaaata
    63121 gtggcagata aatatccaaa attaaataca aaagagatta gacgtcatct agccagatgt
    63181 ggtgtgaagg aagagcatgt ttcaaggagt gtatctactt taagtggtgg tgaacaatct
    63241 aaggttaaat tatgttgtat gatgttatct ccttgtaatt ttcttattct ggatgaacca
    63301 accaatcact ttgatgcaga gacaaaggat gctttacaaa atgctttgaa acagtttaga
    63361 ggaagtataa tcctagtttc ccatgaagaa aaattttata aaggttggat tgataaaata
    63421 tttaatatag aaaaacaatt agtataagtt tatacacaat atacaatatt atttaattgg
    63481 tatttcaatg caaattttaa tgttctagtt aatgtttcac tgcaaataaa ctaaaaaaat
    63541 tttattagaa cataaagtac attaccagga tataaactta atgaggctat ctcaaaatag
    63601 agatagacct cttcttcatt gtggagataa cgaaaataca tttgatttca cccataaaag
    63661 aatgcctcat taactaaaaa ttcaacttga gatatcttca ttaatattaa aatctattct
    63721 aatcgattct attcacaagt ttatatccta gtcctttaac tgttataagt attttaggat
    63781 ttgaggggtt atcttcaatt ttttctctta tatgtcgtat atgcaccata attgtattgt
    63841 cacaaatact actatatact ccccatactt gttcatagag tctttctttt cctataattt
    63901 tatttacatt tttagccatg tagcttaaaa gatgatactc ccttccagtt aactcaatct
    63961 catttctatc tttatataca cggtttcctt ctatatcaat agtaatatct cctattttaa
    64021 taacttcact atctgatggt acaatgcttt gatactgttg tctacgtaat tgcgctttaa
    64081 ctcgaaaagc aatttctctt ggactgaatg gctttgttat atagtcatct cccccactac
    64141 taagacctag tattttgtca atatcatcat tttttgatga taaaaaaaga atagaacagt
    64201 atgaaaactc tcgaattttt ttacacactt ctataccatc tatatctggt aacattatat
    64261 caagaatgac aacatctgga catgctacct tacacagcga aatagcatct aaaccattat
    64321 aagctttaat aatgttttta aaaccatcat ttatgagtac ttcttcaatt aaatctacta
    64381 tatccttttc atcatcaaca agtaatattt ttttattaaa acatgtatcc atattgaaat
    64441 ctctccataa aaatttatta tattctaatc ttgcagtatc actatcttgt ttttttatat
    64501 tcactactct tgcttttaca ttactaatag taacatctct aatagacaaa ttcaatcact
    64561 atgaaaatta agataagttt ctttaaaata aagtgtatga tacattaaaa cctatagaaa
    64621 attaatttca tccaaagttt ataatattag actaatacac ttacagatac agattaatac
    64681 aatagtaaaa taaaaggagt tgtcttaaaa ttgacttttt ctaatcaaac tttaagttca
    64741 actccctttt aaacttttat atgttatttt tattaattct ttatatcaat tataacttta
    64801 attttcaata gtatatatct accactaatt gaattactta ttaaaacata aaatatctat
    64861 ctaagctatt tatttaatat ctacatatat ttatatctat tcttatactt acatatacaa
    64921 aaaatggtta aaaataaggt taaaatctca gcacttggta ctgctaacca tatcccattt
    64981 atatttaaca tatttggcaa tatcaataaa cctatagtta taaatccaaa tgtacgtaga
    65041 aaagataata ttgcagacac ctttccattt gataatgctg taaacataga tgaggtaaaa
    65101 atattatatc cacaaaaaat aaaactaaaa gaaaatatat aaaatccgga ccttgcaatt
    65161 tcataaactc ggcttcctct ttgagaaaaa atctctacaa tgattggtga acatgatata
    65221 gaaaagataa ataccaataa agatgctact gaaataaata atatacaaat cttaaaaaca
    65281 tgatttaact gcgtattatt ttcacttcca tagttataac ttattattgg tgcaacaccc
    65341 attgagaaac ctatataaag cgaagttaaa agaaattgag aataaataat tattgtaata
    65401 gctgcaaccc catcttcacc aattaatttc atcatcatag cattaaataa aaaagtagta
    65461 actgctgttg atagttgacc caccatttca gatgaaccat taaaacaagc ttcaaataat
    65521 attcttttat ctagtctagg tatacaaaat ttaagtaacc ctttattttt tgaaaagaaa
    65581 accatacctg aaatggtagg aattaggtat cctactccag ttgcaagtgc tgctccacta
    65641 atacccattt gtaacagaac aatgaacaca tagtcaagaa ttatattagc acacccagca
    65701 cctaacacta gccataatcc aaattgaggc tttccagctg ttacaaataa acattgaaat
    65761 aatacttgta gtatatttgc agaagcaaaa accaagataa taaaaagata tgaacgacaa
    65821 tatttaatta aaacttcact tgctcctaac catataatga tataatccat aaatacaata
    65881 cctataccag taattattac cccaattaca actcctgata atacgattaa agaaaaagct
    65941 ttatttgctc cctcaatatc accatttccc atcttacgtg ctacaatagc acttcctcca
    66001 gtggcaagca tagttccaat tccaactata agattaataa ttggacatac aatattaatt
    66061 gctgatagag catttgtatt aataaatctt gatacaaata tagtatctac gattgtatac
    66121 aaccccataa aaatcatcat aaaaatagta ggaaatgcaa acttcaatag agtaaataaa
    66181 ttaaatcttt gtgctagtaa attatcttgc tcataaagat tatcttgttc atgattttct
    66241 gaataatata catcactcat tttgtttatt tttctgtaca ttaattattt ttaaaatata
    66301 ttccaaacaa ttagacattt acagacctcc tttctgcata agaattatat ctaattattt
    66361 ggatatagtt ttaattaatc ttgctttttt acacaattat atttctacta aagaaacttt
    66421 taaatcctta ctttaatcat tttatagctt tcagtgcctt tagcgcaaat acttgttcac
    66481 atagtttagt gtcatatgaa acgtatttat atatagttat acattgttta tttttactaa
    66541 tttattaact acttgcactt ttataatgtc tcatacctaa cttccaaaat ctccacataa
    66601 acaatgtaaa caaaaataca attaaaattg agtatattaa tccattaatt gttattgtcc
    66661 cagccaaaat ttgagtcgga attgtcgaca taattccata tggtaagatt aaatagaata
    66721 atactttaaa aacaccttca tatattacac caggaatttt catattcatt ggcaataaat
    66781 tatcttctaa tctcattatc gcagaagatg atataacaaa aaatgaaact gttctaagta
    66841 tgatacatac atcataaaaa agtaatgtca tcaataacac catgaaaata tatattatta
    66901 tcataactaa agttatctct gagtttaact cagatattcc atataaaaca ataagtatac
    66961 ttgctagaat taatggtgat gaaccaatat taatattttc aaatgttaac ctaaatagtg
    67021 ggtctaatgg ttttgtaata tagtagtcta attctccttc ttggattttt cgtggaatat
    67081 cataaatacc aaaaaagaaa atcgtcatat ttatcgcatt tattaatgag aaagttccta
    67141 taaatattaa catctctcct tgttgccatc cccctattga gtctacatga gaatatatac
    67201 tattaaacat taaaagttgt aatataaata atgaactatc tacaaaaaat gctccaaaaa
    67261 aatcaaatct aaataccatc atctttgata atttcatttt taataacata aatattattt
    67321 tcaaattttt tttcatcata tacccacccc atcaaataat gttctcattc ttttatacat
    67381 aactttattt actacagaaa aaaataaaac ccataatgct agaataatta atccttgtat
    67441 tgcctcattg ctgtttctac ctattagtaa catagatggc aaatatgttg tataataaaa
    67501 tggaaatacc ttcataactg ttactatagt ttctggtaag agtacaagtg gtatcattgt
    67561 tcctgtaata aattcaacaa tattttcaat tatcattcta aaaaaactaa tctcaagaaa
    67621 tttaaatgac aaaatcccaa taaagaagtg gagtttcatc ataaaaataa accctagaaa
    67681 aatcatcaaa attgaaatta atatttgaac tggatttgat gtaaaggcaa aatctatttt
    67741 aaatataaaa atccatacaa atgcagaaat catattaaat acaaaataaa aacatgtcat
    67801 tccaaaattt ttagcaataa aataattttg aacattaatt ggaataatca tgtactttga
    67861 aaaggtgccc aattttacac gattacatat ctcttcactg gtactctttg acatatcaat
    67921 acctgctaaa aatgagctta ttatatagta agataacata gagttaaatg taaaaccaga
    67981 gactatttta ttttcaccaa aaattgcttt ccataaaata taagcaaata aaatttttac
    68041 aatcgtaaac accatattaa ccaccacatc aaatctccag ataagttgca ctttaaaatt
    68101 aattttggct acttcataat accttctaat actctgttta aatttataaa acattgaatc
    68161 atttgaactt gcttcattat agttgctcat aatactcatc acttcctttc ttatatattc
    68221 tctctacaat actacctata tcttcttctt caatcattac atctttaaca tcatatttat
    68281 caaaaatcca tttaatcgtt tcatttcctc tttcttttgg cacaattact gatatcttat
    68341 gatttgtttg ttcaacaact ttacaatctt ttggaaatac aatgttagtt tcattggaaa
    68401 aactaactgt tattttttta tatttttgaa aatgattaaa tagtttctct gtagaaccat
    68461 catatatttt acggctattt tctacaacaa tacttctact acagagactc ttaatatctt
    68521 ccatgtaatg agaagtaagt ataatagtag ttccttttgt ttcatttact tcttttagga
    68581 aatacctaat ttgtttttgg gctatagcat ctaagcctat agttggttca tccaaaaata
    68641 atatttttgg attatgtaga agggctacta ttagttccat tttcattctt tctcctaaag
    68701 aaagcgtcct aacttgaaca tttaaatagt cagatacctc aaataattcg ataaagtaat
    68761 ccaagttttt tttatattct tcattagata tatcatataa ttctttaaat aaaagaaacg
    68821 tatctgctgg tgtcaattca aagaatagtt gacttttttg gcccataaca acagcatatt
    68881 gttttttaaa attattttct aatttgttag ggtaataacc cattacagat atttctccag
    68941 aagacggtgc aataatacca gttaacatct taataagagt agttttgcca gctccatttt
    69001 gacctattaa tccaacaaat tctccttctt ctatctttaa atcaaatgat gatatagctg
    69061 ttttttctgt atatttccta ttaaataaag actttacact ccccataaat cctgcctttt
    69121 tctcaaatct tctataagat ttagtcagtt cattaagttc aattatactc attttaacta
    69181 cctccatatt tcataattta tataaaaaaa gtccacaggt atatatctgc ctttctctgt
    69241 gcttatattt aacagcacaa aaacagaaaa ctcctgtgga ctagaaaaat taatgctctc
    69301 tatttcaaaa tagttatcaa aataatacta tacaaaatta ataaaagtgt agcagattaa
    69361 agcctactac accataattt aacaaagtaa tatatatttt aaatactatt tgttgtcata
    69421 tgtcagttat ctataaaggc agaataagac acaaaaatta aatgtattaa aaatacactt
    69481 gaaatttctg attatacaga atatatgtgt ctccaactat ttaattgttg gttaccatta
    69541 tataactccg acatcaaggc actcctctca taatattatt attgatatca tatcataaag
    69601 gttatttatg ttcaagtatg gatttatata ctaatacatt tagcttattt cttcagggtt
    69661 gaatttaaat ttcatttata atattcgttt ataaattaaa aatataatac gtatattaaa
    69721 actggttatt ttactgtaat atttttatta taaaagatat acttttactt atacaggatg
    69781 taatttcttt agttctatat tataataata ttgtaataag agttcaactt ataatacatt
    69841 aaaatataaa ctgtaaatct taagggggta atctatggaa aataatacaa tacaaaaaca
    69901 attaagagat ttatcaaaaa aaatttggca tatttatatt ttaaatccag aagaagaaaa
    69961 ccttaaattt attatttcct tattagatga caaccttgca ttaattggaa caggaaaaca
    70021 tgaattttac gaaacattag aagaatttat tataggtctt gaaaaagacc aaacagaatc
    70081 agagcaaata gactttgaga ttatagatga gtggtattca tgtaccaaag ttacagacga
    70141 agcttttata gtatatggta ctctttgggt aatagaaaaa gattacctag aaaaagatat
    70201 ctatgtagaa atggatactc gatttactat ggtatacaga gttacagatg atatgattaa
    70261 acttatccat gttcaccatt ctattccaaa ctttgaccaa atgaaagatg agtattaccc
    70321 taaaacaata actgaaaaag cacaagaagc actagcaatg gcaaatgaat ttaaactaaa
    70381 atcagaaaaa gaccttatga ctggactata caatagacat ttttttgaag tacacataaa
    70441 agaaatgctt aaaactgttt cacatggata cttttacatc tttgatttag ataattttaa
    70501 acaggtaaat gatatctttg gtcatgttcg aggagatgaa atactaatac atttttcaaa
    70561 tattttgact aaagtattcg taaatgatgc tattattgga agacttggtg gagatgaatt
    70621 tgctgttttt gaatatagta atcaatcaaa agagaatgtt gaaaataagg caaagaaggt
    70681 tttagaatta tgcctagaga gtaattcttg ttctataggt atatctaaat tagaaaataa
    70741 ctctgatact ttccagtctt tatacaaaca atcggattat gctttgtatt attcaaaacg
    70801 aaataataaa ggaaacttta gttggtttta gtacaaaaga tattaaaata ggcaaattta
    70861 ttagagtatc ttgtcctata tactaataag taaagtaaac aacaagctat ctttgcatat
    70921 atttatataa accaactatt cttaataaaa ctacaatagt caacatgacc actattatag
    70981 aatataataa actaaaaaca ttattaacat gattaatatt atattttaat aattttattt
    71041 ttaaaagtaa gtccaaaatg ttatatgttt tgattaaaac tgatgttgat ataaaaaatt
    71101 ttacttaaaa aaacacttag aaaggcttta taaagagcct tttttgcttt tattgattaa
    71161 attttcatat aaaattcctt attaaatttc aaatcaataa aaaaaggctc tataagaagc
    71221 ctccccctat ttttattgat taaatcctaa tatagacaat gcctttgcat catagtaagt
    71281 agtcatctct cttgttgcat cctttaattt acggtaatca aagtctaatg atccaccaaa
    71341 agctgatatt tcagacccat caaacctata ccatttccca tcaatttgta tatagttcca
    71401 agcatgattt aatgatggat ttaatataga tagtgaatcc attcccatta accttgttaa
    71461 taaatgaaag ctacttgcaa aacttccaca tacaccacgt ttatcaacca gattaccata
    71521 gactatgtta caatatttag agtctgcata ttttgcttcg gttaccaatt ttgcagctct
    71581 attagctctt tccatctcag atgcatttct ccagtcaaaa ctatttaaaa aattccttat
    71641 tactgtaagt gtatcttgag cttgtttgta agaaatccaa tttccatcag ctattacttc
    71701 tatagggtca agttttccaa agcctattct ctgatatgag ccacctgaca atgctgccgc
    71761 ataaaatcct agaccttcca tacccttatt tatataataa tatttaccat ctgctcgaag
    71821 ctcaactcca ttgggatttc ctccatagag taaatcccat ccctctttac ctgttgtatt
    71881 aagaccaagt tgtgttaaca ttcctttaag aggatattta gggtcataat tagcaccttt
    71941 acttattgca tttgtttgca ctctgccatc cattgtgcct atattagtct gattacgttc
    72001 atttgcactc tgttttttca agctagatgt ttcatcttct tgatatggct ctgccattac
    72061 tgtcatactc atcatcaata taataatcat ggtaatcata gtagttaata tattcttctt
    72121 catactactc ccccttattt aattcttttt aaaacataaa attattaact cataaatata
    72181 tggttattag taaattgaaa ttaaatctga ttcataaatt attggtttaa tagaagtgta
    72241 ttgaaattgt acctttatat tttcattata taataaactt atttttttaa aacatattgt
    72301 ttaaatcagt acatttatat gttttttttg ttcatctgtt ttatcaaata tattagtctt
    72361 tgaattttgt ttgtattctt cagcattttt atctaacttt tctattctcg actcaagttt
    72421 cattatttct tcttgtgtta aatttataaa atttttaagc atattttcaa gctcttcacg
    72481 agttttacct actaaagata agtcctcaga tactttctct tttttattag aatcctcttt
    72541 ataatccttt ttttgttcta actcttctaa tttttcatca tttaatattt cttcttcaat
    72601 tttttcatta gactctttag tgattaaaga ttctttttca tcatttgtat ttagataagt
    72661 tgaattttca tctaacattg tacttttatt tttatcttct ataatgctat ttttaatacc
    72721 tatttctata ttagaaaagt tattagttgt ttctcttatt tctgatttac ataagttctt
    72781 aattgcgtca tttatttttt tagtataaac ctcttgtcta tattttaaat ctctaattct
    72841 atcattaagt tcttgctttt gtttcataat attagataaa taagtgtctt ttcctacagt
    72901 ttcatttttc ttaaccatac tttcatttat tcttgtatta tttatattac tttcatatct
    72961 aaatgaatat tgacttctat attgactaga tattttcatt tatttcacct ccttaaaata
    73021 aatttatgtt tataaaaacc aacttaactt aattatattt tatcatcaaa agtatacatt
    73081 tacaaatatt agttaatagt tttataggtt cgagcattat tttcaacaaa aaatttttat
    73141 tataaattaa aacaataatt tttataaata tattatttgt attttataat tcatatattt
    73201 ttactttata aattagcaat attgcagttt tgctcttaag aaacatctct atcatacata
    73261 agcatatact ctattatgta ttagtataaa tatgcctttt cttatcttac ataagacctc
    73321 tttataaagg agcctatcgt aacaaatatg tatacattat cacatgtata tatcatcata
    73381 taaaaaatca aactttatta aaaaaattaa taaattgctt taaataatac cacaaaccaa
    73441 atttgccatc aaaatcacat taaagtaaca aattgatggc aaatttaata tattaatagt
    73501 atatagactc atataatgaa caaaaaaact acacttatct tctaatcttc ttatttattt
    73561 ttgagatatt tttaaatttc ttttcttttt ttgctaagta ttcgctttta ttgtctgcaa
    73621 atactgcttc agttttaagc ctacgatagg actcccatct tttaggcgaa agttcttgat
    73681 gagcaatagc ttcccagata gcacagcctg gttctgaggt gtgagtacaa ttacgaaaat
    73741 gacattttcc gaaataagct tctatatctg caaaactttt atctaaacct tctgaaacat
    73801 cccacattcc caactctctc atacctggtg tgtcaataac aataccacca cctgaaatta
    73861 aaaatagctc tcgtctagtc gtggcatgtc ttcctttatc atcatctatg cgaatttcct
    73921 ttgtatttaa aaattctcca cccatcagac aattaattaa tgaagatttt ccaactcctg
    73981 aagaaccaag taaggcaaca gtacagcctg gtttaatata cttagaaatc tgtttataac
    74041 catctggctc tatagatgag gtaacaacta catctacacc caaggctatg gaattaacta
    74101 cttgtaattt acgatacaca ttgtcacata agtctgattt agtaagtact actactggga
    74161 tagctccact ttcccatgtt aaagacaaat acctctccaa tctatgaatg ttaaaatcct
    74221 tattcagtga catgcacaaa aaaacaatgt caatattagc tgcaaccacc tgctcctcat
    74281 ttacctttcc agcagcctta cgcacaaaca agctttttct atgaagcaca tgatgaataa
    74341 tagcattacc atttttatta ttgcaacgat ccaaaataac gaaatcacca actgtgggaa
    74401 aatcagattg tatagtagcc tcaaaacgca gctttcctga aacctctgca aacagtacac
    74461 catttacaca tacagcttga taaaagttct tttcctgcga gataattcga gcaaggtata
    74521 aatcatgata ttccatactt tgagtaataa aattcctatt tagaccatag tcttgtaaat
    74581 tgatttgttt cataccattc attctgtttc ctccttttcc aacttttcaa tgattctttc
    74641 tagtgggaaa gggggctgtg ccagtggttt taatgcaatt gacattaatt tcactgaatt
    74701 atcatcagct gcaatacgat tagaactaag atgtccacag cgtgtacaac gatgaataat
    74761 tgcccactca ccattttttc tcacccacac tccaataggt tccatattag catcacaatc
    74821 tgcagcacgg tcaccaggaa tgatatctac atgaagacta tgtaaacaat gtggacaatg
    74881 atttctatgt tgtgtaccag ctccttcagg aactacaagg caaccacaat ttttgcaaat
    74941 aaagttatcc atacaggaat tttcctgata ataagctcgt tttctatttt tataattcat
    75001 ttttatttcc tccatatcga gtattttcta caaaaaaagt ccacaggtat ttatatctgc
    75061 ctttttatgt ggtatacata tttacctaca caaaaacaga aaacccctgt ggactagaaa
    75121 atttaatatc ttctatttca acataattat attcaaaata atactgtgta aaattaataa
    75181 aagtgtagca gattaaagcc cactacacca caatttaaca aagtaatatg taatattatt
    75241 atttgttgtc taatgttagt tatctataaa ggcagagtaa gacacaacaa tcaaatgtat
    75301 caaaaataca cttaaaaatt ctgattaaac agaacccata tgcgtctcca actatttatt
    75361 tgttggttac cattatatat aactctgaca tcaggcaaga cactccttca ctaataatta
    75421 ttattgaaat tttatcataa aatataagta tgttcaagta taatttaata tattcatata
    75481 tttatgtttg tctcattttc ttattctata aaatctagtg gtattttaaa atttaatgtt
    75541 cacctagtat taataataaa aattaactgc tattatttgt tttctcattt tatgcctatt
    75601 gctcaattta tctcacttaa attaataaca actgtctttt catacaaaac ctacaatcaa
    75661 gtttttccat atattctaca tgcatagtct atttttttga tataaaataa cattcatatt
    75721 tgtaaattta tttaattttc aaataagtat attgaataat aagcaattct attgtattat
    75781 tgtaattgta gaataaaact aaatcggcaa aactagagaa atttagtgac gcaaagctat
    75841 agggactaac gcttataaaa taaactatga gttatgtcag ccagttgcca aaaagagata
    75901 ttctttttgt ttttatgaaa gttttttagg gggataataa tatatatgtt tagagataaa
    75961 atggatagat gtacacatat gttgactgct tatattggta gttcatatga ttattgtgat
    76021 tttatagata cacaactaga tgattttata ctagagtacg gagaaaatgt ggtagaatct
    76081 tgtttgcatc aagtgatggt attagtaagt aagtataatt aaatagattt ggttttctag
    76141 agaacccttt ttagttttat ctactttaaa tagccttatg ttagaaagct aattaagata
    76201 gatttctagt attcataatt ttatttttta tttaaaatac atataataaa gatgtaaatt
    76261 tgtatcaaat aataaatatg agaacttaaa ttctcttatc tatgtgaaaa taaacatctc
    76321 ttaaaatgaa attctgtaaa cataaatgat tttttagttt gaaggattag attaacaaaa
    76381 ttataaattt gcaaataagc tatattaaaa aatataataa ttttttatat aacttattct
    76441 tttataactt ttaattttaa aagaggagaa tgtatataag agtattcaat gtactagaaa
    76501 aaatcaaaag aaatattaga agaaatggat attgagtaat caaagaaaag attttgatat
    76561 tacaaatgat atgtttcaag aaagcattcc tatcacaaca aaaattattc ttgaagacat
    76621 gccttcaaat gatgaattaa atcatgtttt ttcaattagt aaaaacagct aatatttcaa
    76681 tgctaaagga atcttggaat tttgatatac caatacctaa caaagaaatt gaagtatttg
    76741 atactcaaga tagtattaat ggagatggac aaagttattt tattcaagga ttttctgaaa
    76801 aaaatttcaa aaaagttttt aatttaaaag gtggtatagt tgtaagcaaa gataatatta
    76861 atgaaataga aaaatatatt gataaattta aaagagattc tgttaacatt aataaaagta
    76921 ataaaaataa aattgaagaa gattttaaaa aatataagtt agaagttaaa aaagatgata
    76981 agtatatata taagagaaat tatgaaaact atgtagtttt aattataaaa aaagatgaac
    77041 aaaaattata cagtttaata tggaatcagt aggtacatat gtattattaa gaattataaa
    77101 taataaaaat aaattttagt caatatacaa aaacctttta aattgtctgg aaatcacctc
    77161 ttcatttgtt ataaaaacat acaacaaatg aagaggtgat tttatggttt taaaaaaata
    77221 attataagtg gatatgtgct ttcacatgtt tattaacatt tgtaatgcct atatttgcta
    77281 atgaattata atataaaaat attaaataat attcaactat agattatgta aattattcta
    77341 tgaaaaaaat gagttgtata aaatctggct actgtagatt gactatttct tttaaaatta
    77401 caattataat aagttttata gaattaaaaa taaaacttta gagatttttg ataacattgt
    77461 agactaaatt tgccaccgaa atcgctttac agtggcaaat cggtggcaaa tacaatatat
    77521 tattagtata taatctatat aaacattact attgtttgat tatcttagct acagtttcca
    77581 catgtgtaga atgagggaac atatctacag gttgtgcctc aacacattta aatccgtgaa
    77641 catttagata gtctaaatcc cttgctaaag tagaaggatt acaagaaaca tagacaattc
    77701 tttccggatt cattgaaaca atagtctcta gtaccttttc gtcacatccc tttctaggtg
    77761 ggtctacaac tactacattg gcagtcttac cctctctata catcttaggt acaatttcct
    77821 ctgcctttcc aacataaaat tcagcattat gtatattgtt taatttagca tttatcttag
    77881 catcttttat ggcatcatct ataatttcta ttccataaac ctttttagcc ttttgtgcca
    77941 aaaataaaga tattgtacct atcccacagt aaatatcaaa aacagtatca gtatcattta
    78001 aatttgcata ttcaagagcc ttatcataca atactttagt ttggacaggg tttacttgga
    78061 aaaatgataa tggtgaaatc tcaaacacta agtcacctat ataatcgttt atttttccat
    78121 ctccatatat aactatattt tctcttccta gaatagcatt cgtatctttt tgatttacat
    78181 ttacaaccaa agtcttaaat ccaggtatat tttccttaag cactgaagct aattctttaa
    78241 gatatggaag tttgtttcca tttgctacta atacaaccat tacttcttta gttgtaaaac
    78301 ctatttttgt tactaaatgc ctaatcaacc ccgtgtgagt cttttcatca tatatactta
    78361 ccttataggc ccttatatat gtttttatta ttttaacaat tttatcattt atctcatgtt
    78421 gtattacgca tttttctgtc gatattacat catgagtctt ctttttatag aagccaataa
    78481 ttggaatacc attattcttt tgtattggaa attgtgcttt atttctatat ctatatggat
    78541 tatccattcc tatagtgtca tgaacttcta catcctctaa cttacctatt ctcgaaagta
    78601 cttgtttaac ttcatttgtt ttcatttcaa gttgtttatt ataatctaag tcttgtatct
    78661 gacaccctcc acaatcccta agattgtcac tacacactct tttcaccctg aatggagact
    78721 tttctattat ctcaacaata tctcccacag cataattttt ctttacttta ttaatcctaa
    78781 ctttaacttt atcatgtatt aatccgccct ctacaaaaac tgtaatacca ttgtactttc
    78841 ctactcctac tccgccttga ccaatgtcta ctatatctac aatatacatc tcgtttttcg
    78901 aaagcataaa tcaccctcca atcaatctat tatatttaaa tctttacaaa cttttttctt
    78961 taaatttata ttaaaatatt gctattaatt aaactatatt ttttactaag ctacaatatt
    79021 ttattttacc aaaaaaaaag gagcttataa agccccttag taaataaatt tattattttt
    79081 cttataaaac tctagttgaa cctctatata ccacgcctct tgatgcatcc acagttacaa
    79141 cttctccatc ttttactaga tttgttatat cagctgcaga cacaataact ggtatatcta
    79201 aatttatacc tacaatagct gtatgtgatg tcattccacc attctcagtt actacagctc
    79261 ctgctttttc tatataattg ttcatttcag catcagtagc agtagaaaca agtatgtcgc
    79321 cttcattaaa gtctacacaa gcatttccat tctttattat acgaacttta ccttctactg
    79381 tttgagtacc tacacctata ccttgcacga tttcttcgct tattacatga acctttatta
    79441 aattagtagt tccacttact cctactggta ctccagcagt tataactact aattccccat
    79501 tatctatata atcagcttgt ctagctgcct caattgcctt ctctataact tcatctgtat
    79561 ttcctgcaac agaagactta actggatata ctccccatgt aagagctaat ttattcatag
    79621 tcttttcatt atttgtagta gctattattg gagattttgg tctaaattta gataccattc
    79681 tagcagtata tcctgaagaa gtagatgtta ttatagctga tgcatttaaa tctactgctg
    79741 ttgtacaagt tgcatggctt attgcatctg ttacagtaac attgttagta ccattttcct
    79801 ttagtaatct atcataatct aaagtctctt ctgttctttt tgctattgta gccatcattt
    79861 ttactgcctc tacaggatat tttccagcag cagtttctcc agataacatt atcgcatctg
    79921 ttccatcata tatagcattg gcaacgtctg taacttctgc tcttgttggt cttggatttc
    79981 ttatcataga atcaagcatt tgagtggcag taacaactgg ctttgctaat tcattacatt
    80041 tttttatcat cattttttga actattggca tctcttcagt tggtatctca acacctaagt
    80101 cacctctagc caccattata ccatcagaaa cttttaatat ttcatctagg ttctctacac
    80161 cttcttggtt ttctatttta gatattattt gtatatcagt tgcattattg ttctctaata
    80221 cttctcttat tgctagtaca tcagatgcct ttcttacaaa agaagcagct atataatcta
    80281 ttccttgact tattccaaac tctatatcac ttatatcttt aggagttatt gctggtaaat
    80341 ttatcttaac accaggtaca tttactcctt tatgattttt aactattcct gaattttcaa
    80401 caacacaaac tatatcttct ccatttattt cttttactct taagccaact aaaccatcat
    80461 ctattagtat agaatctcct gatttaacgt cttcagcaag acctttatag cttactgtac
    80521 acatttcttt agtccccata atatctttca tagttatagt gaacttttgc ccttcttcta
    80581 aaaatacctc tgggtcttca aagttacctg ttctaatttc tggaccttta gtatctaata
    80641 atatagcaac tggcttattt aatttttctc taactttctt tgccatatcg attctttctt
    80701 tatgttcttc atgcgaaccg tgagaaaagt taaatctaca cacatttaga ccattttgca
    80761 taagttgagt taaaacttcc tcactttgtg atgctggacc tagtgtacaa acaatttttg
    80821 tcttctttac attatttaac atatttgctc ctcctgagat attattccac agatttattt
    80881 ttaatactaa aacttatata gataatattt ttgccatctc ataagcttct ttatcaaata
    80941 ctttcttttg agctaaagct tcacttattt ctaaatcaat tattttgttt tcttttattc
    81001 ctacaactct agctgatttt ccatctaata ataattctac tgctcttact ccaagtctac
    81061 ttgctagtat tctatcagat acagttgggc ttcctcctct ttggacatgc cccaatacag
    81121 tgactcttaa atctgctcct gactcttttt taagttcctt ttctaaatca ctagcacttc
    81181 cgactccttc tgctaaaacg attatactat gtctcttacc tcttttttga gtagtcttta
    81241 atcttagagc aacttcatct actgtaattt ctacttctgg tactattata gtttccgctc
    81301 ctcctgcaag acctgcatat aaggctaaat ctccacagtg tcttcccata acttctacta
    81361 tgttaactct ttcatgagat gatgatgtat ctcttatctt acctatagca tctataatag
    81421 tattcattgc agtatcaaat cctatagtat aatctgtata tgctaaatcg ttatctatag
    81481 ttcctggtat gcctatagct gggaatccta agtcactaag tttttgagct cctgcaaatg
    81541 aaccatctcc accaattaca actaagcaat caattttata ctttttaaga atttttactg
    81601 cttttaatct accttcttct gttttaaatt cttcacatct ggaagatttt aatatagttc
    81661 ctcccctgtg tataatatct ccaacagaag ataagttcat ttcagttaaa tcttcttcta
    81721 gtaatccctt atatcctcta ttgattccat atactttgca tccataatat attgctgatc
    81781 ttacaaccgc tctaatcgca gcattcattc ctggagcatc tcctccactt gttagtaatc
    81841 ctatagtttt cattttttac ctccttggat tttatgtcaa ttttttatta taatcattgt
    81901 tattgtattc taatggactt tttttgtccc tatatcactt tttaatccca tcaagactaa
    81961 aaaaattaaa tgtccttaaa tgtccatttt gtgatattat atcacaaaac ggacaatatt
    82021 tttcatatta ttataatata tttagatttt tatataaaaa atcaagcttt tacttttatg
    82081 ttatctttag gaagtaactc ttctaagtta tttataaatt catcacatat acaagtcaat
    82141 gccccggtca ttttatatgc tttacgttta ccatttatat tttcatccat agggtataag
    82201 tatatactgt cattacctgg atattgtttg gctatttcta caatattatt agttgtatca
    82261 gtatcagaca tactatctat tttcaaatac aattttttac cactttctgg cttaatattt
    82321 tctacatttc tagttcttcc tgaattgtag tttctatctg caaagtcagt atcatcattt
    82381 atatctttta tctctctagc tataagtttt gcattttcgc cttcttttat acttaatgtt
    82441 ccttttacat atattatatt atcttcattc aaaatgacat tatacttttg taataattga
    82501 ggaaaaacta ttatttctat agcaccatac aaatcttcta attcaataaa tgccataatt
    82561 tcatttcgtt ttgttgtttt aatagtttta gttacaatca ttccacccat tataacatct
    82621 gtttcattca tttgtaggta tgactcttct tcctctttta atgaatttaa ttttccatta
    82681 tccatagatg ttttttcttg tagttctttt tcaaattgtg ataaaggatg tccacttaca
    82741 tacattccca agacttcttt ttcaaggtta agtctctctc tttcttcgta ctcttgcctt
    82801 ttaggcaaac tgtatatttg ttgaaaatca ctatcttcct cactatctcc aaaagcatca
    82861 aataaagaaa tttgaccttg aacatttttc tttctatcca tagatacact ttctaataaa
    82921 ctttcataac cagccatcag actagctcta ttttcactta tattatcaaa agctccacat
    82981 tttattagac tttctattac tctcttattt gtatcttttt ggtctaatct tttgactaaa
    83041 tctactaaat ctacaaataa tccattagat tctctttcag cgattatatt gtttattata
    83101 tttacgccaa cattttttac ggctgctaga ccaaatctta tattgtcgcc ttcaactgaa
    83161 aactttgaaa aacttttgtt tatatctgga ggtaatacat ctatttctag tgctttacat
    83221 tctcttatat actcaactac cttatcagta tttcccatta cactggttat caatgctgcc
    83281 ataaattcaa ctggataata tgtttttaga taagctgtct catatgctaa aaccccatat
    83341 gcagctgcat gtgatttatt aaatgcatat ctagcgaagt ctatcatatc atcaaatatt
    83401 ttattagcta tttcctcttc tacaccattt ctgatacacc ctgcaatttc tatattacca
    83461 tcttcatcaa atttaccatg aataaaatat tgtctttctt cttccatcac gtccatcttt
    83521 ttcttactca tggctcttct aactaggtca cttcgtccgt aactataacc acctaaatct
    83581 ctaacgacct gcataacctg ctcttgatat accaaacaac catatgtaac ttccattata
    83641 ggctttaatt tttcatgtag atatgttaca tcttttgggt tgcttttatt ttttatatat
    83701 gcaggtatag aatccattgg acctggtcta aatagggata ttcccgctac aatatcttca
    83761 aaattgtctg gttttagctg tttcataaaa cttctcatgc cagcactctc caattgaaac
    83821 acccctagtg tatttcctga tgaaagcatt tcatatactt tcgggtcgtc ataatccatc
    83881 tttgaaaagt ctattttttc tgtgtaattt tttataactc tatttttttc tattaaatca
    83941 agagtatctc ttataactgt aagagttctt agcccaagaa aatccatctt taaaagccca
    84001 agttcttcaa gtgttgtcat agtaaactgt gttgtgattg catcttgatg tttgtacaaa
    84061 ggtacatatt catctacggg attttttgat ataacaactc ctgctgcatg agtagaagca
    84121 tgtcttagca ttccctctat ctgttttgat atatttatta tttcttttgt ttccgggtct
    84181 tggtcataca attctttaag attaggattt gtatctaggg ccttatctat tgtcattcct
    84241 aaagcaaatg gtatttcctt ggctaccttg tcaactttat tgtagcctat atccaatacc
    84301 cttccaacat ctcttattgc agcttttgca cccattgttc caaaagttat tatctgggct
    84361 acatggtcat caccatattt tctctttaca taatctataa cttcttctct tctctcataa
    84421 caaaaatcta tatctatatc tggcatggat atacgttctg gatttaaaaa acgctcaaat
    84481 aatagagagt actttattgg gtctatatca gttattttaa gtgtatatgc tactatcgaa
    84541 ccagccgcac tacctctacc tggtcctact ataatattat tttctttaga aaaatttata
    84601 aaatcccaaa caattaaaaa atactctaca taacccattt tttcaattac atctaattca
    84661 taatttaatc tctctagtat ctcattgcta ggattatcat atctctcttt taatccatta
    84721 aaacacaact cccttaaata agtttctggt gtatatcctt ctggaacatc atacttagga
    84781 agatgtatag tattaaaatc aaactccaca ttacacatat cagctatttt cacagtattg
    84841 tcaatagcct ctaatgcata tggaaataat tcttccattt cttctcttga ttttaaataa
    84901 aactcatcac taccaaatct cattctattt gggtcattta atgtttttcc catttgaata
    84961 cacataagaa catcatgtat tttcgaatct tctttattta catagtgaac atcattagta
    85021 gcaactagtg gtataccagt ctcttttgat aattttacta aaccagagtt tacttctttt
    85081 tgctcaggta aattgtgatc ttgaatctcc aaaaagaaat tttcttctcc aaatatgtct
    85141 ctgtagtcaa gagtaaattg ttttgctttt tcataatttc tattcattaa agcacgtgct
    85201 acatctcctg caaggcatgc agaaagtgct ataatccctt tgttatgttt tttaagttct
    85261 tccatatcaa ctctaggctt atagtaaaaa ccttctacgt atgaagttga aactattttt
    85321 attaaatttt tatatccttc catattctta gctaacagaa ctaaatgtcc ttgatatttg
    85381 tcatagtttg ggtctttatc tctcaatcca cgtgcagctg tatagacttc acaccctata
    85441 attggcttta ttccttcttt tatagctgtt ttgtagaaat ctataacacc aaacatacaa
    85501 ccatggtcag ttatagctat tgagctcatg tttagttcct tagccctttt tataagtttt
    85561 ttcaccctcg aaaacccatc aagtaaacta tactcagtat gtacatgaag atgagcaaaa
    85621 tctttgttca ttaaatcacc tcctgcttta taattttaat tttaccacaa atatatgtcc
    85681 taaaacaaaa acagagactt ttatctcaaa ataggaatta acttcaacgt ataccattat
    85741 atgttataaa ttaatgctta ttctgagatt gtcccctcaa tttattgcta tgattttttt
    85801 ttcaaatctg ttgcaatttc ttctattttt ctaagtctat gattgactcc agattttcct
    85861 attggtggtt ctaacatctc tccaagttct ttgagagtca tatcctcata ctcgattcta
    85921 atcttagcta tctcttgtaa attttctggc aaactgctaa ttcctatagt ctcttgtatg
    85981 agcttaatat tttctacttg tcttactgct gcatttactg ttttagaaag gttagctgtc
    86041 tcacaattta ctatcctgtt tacattattt ctcatttctt ttactatttt agtattttga
    86101 agacttaaaa gagcatggtg tcctcctata atactcaaca aatctgatat ttgttcactc
    86161 tctttgatat aaacaacgtg attatttttt ctagccacaa ttttactatt aaaacctaaa
    86221 gagtttataa gttcttttag agaatctgca aactcctcat tattagttac aaattccata
    86281 tgatagttct tttctgggtc gcttatagaa cctccaccaa gaaaagctcc tcttatgaaa
    86341 gctctcttac atccttcatg cttaattaag ttctctgaaa ttttgtttat agtaaaaaat
    86401 ccttctttat cttcaagtat acctaacttt tttaataaca tttctgaacc catttcgctt
    86461 gttaccatta atacataact gttatttctc tttagcattt gattcttatt tactgagatt
    86521 gtagtattga tattaaaatt cttttttaat aatttaaata ctttacgggc tattgaattt
    86581 aactctgttg ttatctttag atttagcttc ttatatccaa caatttgtat acttccccct
    86641 gatttaacta gagctgacaa ttcagctata ttacaacatt cattcccaga tataactctt
    86701 gctagttcat ttttggtttc agttgaaaaa gacatatcta tcacctatta actaattttt
    86761 ctttaacctt ttttttattt cttgtaaggc aacctttatt atctcctttt catcatcata
    86821 cctagctaag tctactactc tatctaggtg gataaattta gcatcaataa agccttcctc
    86881 tttttgtgga atagtatcca tattctttgc ttgcatcaaa taccaaaaaa ctgttttatg
    86941 aactgctcta ttttcatccc agttttcttt gaatgtatag tgtatttcac ctaaatattt
    87001 caatatatct gcttttactc cagtttcttc acttacttca cgtaatgctg cctcttggtt
    87061 attttcccct tcttctactt ttcccttggg taacacccaa tctccattga acttccttag
    87121 taaaagaatc gtattgccaa acaggactac accaccagca ctaacctctt ctctcatcga
    87181 tgttcactcc ttaaaactaa cataatgata aggatttcta cacaattttt taaaatcctt
    87241 ttttactaac ttttgttgta attatgattt agggctaact caataactat gttagatata
    87301 tactttgcat catgtcttat ataattattt tttatttcaa ttaaattctt ctctacagtt
    87361 tttataccca tctcttttaa tttatctttt tgctttttat ctaacaagac ttgctctgct
    87421 ccatcttgtt tatataagtc aagcatttct tctggcaata tctcattatt tgcgattaca
    87481 taatctatta aattctcatc agtgtgtttt actatagcat taacatgctc taatacattg
    87541 tacccttctg tctcacctgg ttgagtcatt atatttgcta tatatacttt tggagctaca
    87601 gacgatttaa tagcgtctac aatcccctct acaagtaaat tgggtattat acttgtatat
    87661 aaacttccag gacccataat tataatgtca gcatcataaa tagatgcaat aacatccttt
    87721 aatggtttta catcttttgg atttaaaaaa attttatcaa tagagctttt ttgaattttt
    87781 gactcttcag gtatactaga ttctccattt attatattgc cattttctaa tttggcaact
    87841 aaatttacat cttccaaagt tactggtaaa actcttcctg ttatagcaaa aatttcactt
    87901 aatttatata cagctttttc aaagtttcca tacaacccat tcatagcagc caaaaacaaa
    87961 tttccaaaac tctgaccttt taaaagccct tctgtaaacc tatattgcat aacttcattc
    88021 attgttggct ctatatttgc aagtgctaat aaacagtttc ttatgtctcc tggtgggagc
    88081 attcctaagt cttctctcaa tacacctgaa cctccaccat catcagcaac agttacaatt
    88141 gcagttatat tttgcgtagt gtgtttaaga cctcttaaaa ataccgattg accagtacct
    88201 ccacctatca caaccacatt tggttctcta ttttcaacaa tagacctttg aaatagtttt
    88261 actttttcat tttttgcttt tttatatata aataacgata caattaatgc aatccaacct
    88321 aaaattccta caataataag taatttagcc atgtttgcct ccattatcgc aacatagagt
    88381 ctctatgttt ctttacaact ctatatccct tattagataa atcctccgct ataagatttg
    88441 ttatagtaac tgacctatgt cttccacctg tgcatccaac accaattact agatgttgtt
    88501 ttccttcctc tatatattga ggtactaaaa aatgaatcat atctaaaagt ttcacataaa
    88561 attcttcact gattttagaa ttcataacat aatctctaac ttctttatca tcaccagttt
    88621 tagctcttaa ctcttcaaca taatagggat ttggaagaaa tcttacatca aatactaaat
    88681 ctgcatcagc aagtatacca tgtttaaatc caaaagatac cacagaaata gttaggtttg
    88741 gattatcttc accagaagaa tatattttct ttatttcttc cttaaggtct ttaggtttca
    88801 tgttagttgt atcaattata catgtagata actcctttaa aggttccatt atctttcttt
    88861 ccatttttat accttctgga atctgcatat cttttgccaa tggatgattt cttcttgtca
    88921 ttttatatct ctttaacaat acatcatcat tacaatccaa atataccatt tcatattcat
    88981 aattttcttt ttctaaataa tttaagcttt catgaagcgc ttcaaaaaac tttctccctc
    89041 ttatatctat ccctagagca actttatcaa tacttgaatt tggttgataa cataattctg
    89101 caaatttagt tatcaaagca ggaggtagat tatctacaca ataaaatccc atatcctcta
    89161 aagctctcat tgtctcactt tttccagatc ctgaaagacc tgtaactata acaaatttca
    89221 ttgctaactc ctccctttta tcttatgttt attatattat aatgttttct actaacgata
    89281 tatccagatt agagtcagat atagtcttca tagctagttc aaaatcacca actctttctg
    89341 gacaatgtgc atctgagcct attataaatt tattttctag cccttttatt ttatttaatt
    89401 gatttacatt caaaaaagaa tggctactat ttatttcaag tctagtattt gtcttttttg
    89461 ccgtctttgc tacttcttct atatacacat cgcctttatc tcctggatga gtaattataa
    89521 aaatatcatt attacttatc gcatttatta cagcttttgt attatattct tttgcttttt
    89581 cagttttaaa aatatagtta ttacaatgat ttaataagct tcttaatgat gttggagtag
    89641 aaccaaaatg atatccagcc ataatataat caaaatctct aataaattta tcatccatat
    89701 ctatatttcc tttatcatct aatatgttac actccatacc taaaagtata tttatatcag
    89761 tgtacttatc atttaaataa tctacttctt ctctcatttt gagaatatct tttttcttta
    89821 caccatatgc aatatgttta taactatggt cagatattcc tattgttttt attcctttag
    89881 aaatggctac ctttacatta tcctcaatag tccctttgcc atgactatat aatgtatgtg
    89941 tatgataatc agccagtatt ttcatttgtt aatcctctcc aagtattttg acttcttctt
    90001 ccaacataac cccaaacttg gcatatacag cactttttat aacatatatt aaatccaaaa
    90061 tatctttagc acttgcttct ccttgattga ctacaaatcc acaatgcttc tcagatactt
    90121 gtgctcctct taaagtaaga cctctcaatc cagtttcttc tattaattta cctgcaaaat
    90181 atcctgttgg tctcttaaat gtacttcctg cactagcaaa atttaatggc tgtttagtta
    90241 ttcttctcgt cgctaaatca tccattaaac tttttatttc atcataattt ccttcttgta
    90301 attctaattc tgctgataaa gctatatatc cgtttttcga tattatactt tttctatacc
    90361 caaattccat ctgttcattt gataattcaa atatattgcc ttccatatcc atcagtctta
    90421 ctgacttcac tatgtccttc atttcaccac catatgctcc agcattcatg gctaatgctc
    90481 ctcccaatgt gccaggtatt cctgatgcaa actcaaaccc ttttaattct tgcttttgga
    90541 gagctttccc taaaactgat aataaagctc ctgactgagc agtcatccta gtatcattta
    90601 tctcataaga attgaaatta tcagctaatt ctattaccac tcctcttatt ccaccatctt
    90661 taattaaaat gtttgaacca tttccaatta ttaaatacgg aatagattct ttttttacca
    90721 acttaagtac attttttaat tgttcttcag ttctaggtct aactaatata tctgctggtc
    90781 ctcctaccct aaatgaaata tgttttttca taggttcatc gacttttata tcctctttac
    90841 ttaatatatt taataaattt atatatatat cttgattatt cattgtattt cctcccaaat
    90901 tatactgaac tttagctgtc attattattt aaattacatt agtatatagt attaactata
    90961 ttcaataata tatgattttg cttatcatat ggattttata ttttaagctt cttaattaca
    91021 aactatattc aataaatata taataaagta aaaaaaaaaa aataacaaca tataaaagaa
    91081 tataaataat ttaaaaaaag catcaatatc actgatatca atgctttaaa aggcaattta
    91141 attcgtatta tttatctaac tatttttgac atagcaaaga taataaatcc ctccaactac
    91201 tatggaacct ccaacgatat ttccaagtgt tacaaatacc aaattagtta taaattgaac
    91261 catagttata tttgctccta atgccattcc cattggtata aaaaacatgt ttgcaacact
    91321 atgttggaat ccacataata caaatagcat tattactgtc caacatgaag ccaattttga
    91381 cattatatct tgagatgctg tagccatcca tacagctaaa acgactagaa tattacaaag
    91441 tattgctttt aaaaacattg atgctatagt tgaattaacc ttagcttctg ccacagctat
    91501 agcttttgta gctgcatctc ctgtcaatgt agaagaataa aacacaagtg caactagcaa
    91561 aattgaacct actaaatttg caaaataaac cagtccccag tttcttaaca tttttcctaa
    91621 tgttattttt ttgtccataa gtgcaatagc cattaatgtg tttccagtga ataattctgc
    91681 tcctgccact actacaagca taagacctac tggaaagacc atagcactta aaaagctagc
    91741 tacccctggg tctatcttgc caaaagtttg actaactatc atactcccca atgccccaaa
    91801 acctataaat gctcctccaa ataaacctaa tagaattgcg ttttgtgtcg aaatatttgc
    91861 ttttttaatg cctgcactta tagttgcttg tgcagtttcc ccaggtgtca agaatccttt
    91921 actcataaat ccttccccct taaaaattat actttccctt gtctttttat ggcaataatt
    91981 atataataac aatatgatat ataataaatt ttattaacat aaaaaatata ctatatactt
    92041 atatatactt gtctcatata attatactat ttattatata acaactttgt taatttcgaa
    92101 ataatttata ttgaatttga aaaatttacc ttttgattat ttattttact ttttaattat
    92161 tgaggtatta tatataatag atatatgttt gtgttattat atataattac ttattttaat
    92221 aaatatttga aggagggaat tttatgtttg atatatcatt tttcgaaatg tcaatatatg
    92281 aaatagcagt tactacaata tatataatta atttcatggt tatactaaac cttatcttta
    92341 gagaaaaaag aaacataaat acaactttaa catggcttct tatattagta ttgattcctg
    92401 ctcttggatt catactttat atagcttttg gcagaaatat ttcaaaaaac aatatgttta
    92461 gattgaaaga aaaggatgat aagataatca aaagtaatat actagatact caggttaaac
    92521 tccaatctac atctgaaatt gattcagata tacatcaaca taaggatatg atttatgcat
    92581 tggctaattc aaataatgct cattatacca ataataacga tgtgtggatt tatgctgaat
    92641 ctagtcaatt ttttaacagt cttcttgagg aacttaaaaa agctaaaaaa tatataaaca
    92701 tacaatttta cattttcaaa gatgacaaaa tcggaactga aataatagac attcttatag
    92761 acaaagctaa agaaggtgtt gaagtaagac ttttatttga tgcagttggt ggtagaacac
    92821 taaaaaatag tacactttcc agacttaaag aaagtggtgt taaagttgga agcttcttcc
    92881 catcattctt gaaaattgta aactttaact taaactatag aaatcaccga aaaattgttg
    92941 tcattgatgg taaggtagga tttgtaggtg gatataatgt tggtgatgaa tatttaggta
    93001 gaaatccaaa atttggtcta tggagagata cacatactaa gcttactggt gattgcgtaa
    93061 ttgacctaaa tatgagattc atccttgatt ggagatatac aactaaagaa gacttagatt
    93121 tagaaaagta ctttatagaa gaagatacaa attctaatca tccttctgaa aatattggga
    93181 ttcagatagt atcaagtggt ccagatatat cagaacttga tgagattaaa tatggttacc
    93241 ttaaaatgat tcagaaagct agaaagtata tatacataca gagtccttat ttaatacttg
    93301 actcaacttt tatagatact ttaaaaatag cttgtttatc tggtgttgat gtgagagtta
    93361 tgattccttc taaacctgac catccctttg tatactgggc atcatattca tatgctggag
    93421 aacttttaaa gtttggagct aaaatctata cttatggtca aaatgcattt ttacatgcta
    93481 agacaatagt tatagatgac tctatatgct ctataggaac agctaatatg gatatcagaa
    93541 gttttgagct taatttcgaa gttaatgcat ttatgtactc ttcaaaaaaa gcattggaac
    93601 aaagaattat atttgaaaat gatattttaa attctaagga aataacatta gatatatata
    93661 attctaggtc tacttatata aaaatcaagg aatcaatttc aagactatta tcagcagttt
    93721 tataaatctt ttattttata aaaattttac attttggttt attttttaaa gttttttata
    93781 tgtattattt tttttttatt gaatttagct catttttttt atttttttta actattctga
    93841 attattttat attataatag actagtatag tttttatttt taataggtaa cttttttgca
    93901 ttgtttttat aaataaagaa attgttgtat attattcttt ctttattgtt ttggttttgt
    93961 tcacccacat aatgttgggg tcaactcatg gttaattatt ttatgaaaaa taataacttt
    94021 aaaaagaaaa gggggatttg ttatgtgcga ttttatttca cacaacaagc aattatttga
    94081 cgaactagat atatttattg actctcttgc aacaaaggaa ggtgcgttaa tacaagttct
    94141 acatgaagcc caaggtatat ttggatatct tccaaaagaa gttcaacttc atgttgctag
    94201 aaaacttggg gtagctcctg caaaggtata tggggttgtt acattctatt cttattttac
    94261 tacagaacct gtaggtaagt ataaaatcag tgtctgtcta ggaactgtat gttttgtaaa
    94321 aggtgctgac aaaatcttaa gtgcttttga aaaacagctt ggcataaaag ttggagaaac
    94381 tactagtgat tttaaatttt ctttagaagg tttaagatgt ttgggggcat gtggtttagc
    94441 tccagttgtt actgtaaatg gtaaagttta tggtaaagtg aaacctgacc aagtaagcga
    94501 aatattagat acttatagag aattagaatt gaattgttaa gaggggtgaa taaataatgc
    94561 gtaaagtaaa ttcatttgat gaattaaaag ttttagctga tgagctgaaa cctaatctta
    94621 gcttaagaaa aaattattct aaggaaaatg tattaagaag agaattactt gtttgttgtg
    94681 atactggatg tacatcttca aacagtctag aaatagttag tgaattagaa aatgaaataa
    94741 agaaatcagg aatccaagat aaagttagtg ttcgtttgac aggttgtttt ggtttctgtg
    94801 ctcaaggtcc tattgtaaaa gtttatcctg ataacgtttt ctacgtaaaa gttgagccat
    94861 ctgatgctga aaagatagtt caaagccact taattagaaa tacagttgtc gaggaattat
    94921 tatatgagga agaatcttta agtaaaaaag ttgaagaaca agaagaaatg tctttctaca
    94981 aaaaacagtt acgtatagct ttaaaaaatt gtggtcttat agacccagat agtatagaag
    95041 aatatattgc caatgatggt tatttagctc taggcaaatg tttaacttct cttactcctc
    95101 aagaagttat tgcagaggta aaaacttctg gccttcgtgg tagaggtggt gcaggtttcc
    95161 ctactggctc taaatgggaa gctgcttcaa aaaatccagc tggtccaaca gataaaaagt
    95221 ttgttgtatg taatgctgat gaaggtgacc caggtgcatt tatggataga tctgtacttg
    95281 aaggtgaccc tcatagtgta ctagaagcta tggcaatatg tggatacgct ataggttctg
    95341 atacaggata catatacata agagcagaat atccaaaatc tatagaaaga ttaaaagtag
    95401 ccatagctca agctgaaaaa tacggtttac ttggcgaaaa tatcttaggc actggattta
    95461 actttaaatt agaattaaaa tatggtgcag gtgctttcgt ttgtggtgaa ggtacagcgc
    95521 taatgcattc aattgaaggt agacgtggtg aacctagaat gaaaacttat agttcttcta
    95581 agagtggtct atggaaatct cctacttgct taaataacgt tgagactttt gctaacatac
    95641 ctgcaattat acttaagggt ggagattggt ttgccaactt aggtactgaa gattctagtg
    95701 gtactaaagt ctttgctctt ggtggaaaag tagaaaatgt aggacttgtt gaagttccaa
    95761 tgggtactac tttaagagat attgtatttg aaattggtgg gggaatccct gaaggtaaga
    95821 aatttaaggc tgttcaaaca ggtggaccat ctggtggatg tataccaact gaacatttag
    95881 acactcctat agactttggt tcattaagtt ctatcggttc aatgatgggc tctggtggta
    95941 tgcttgttct tgatgaatct gactgtatgg tagatatagc caagttcttc cttgagttta
    96001 ctgttgaaga atcttgtggt aaatgtacac cttgtcgtat aggtactaca agattattag
    96061 aaatattaac taaaattaca gaaggtaatg gtactctaca agatttagat gacctagaaa
    96121 accttgctga aactatacaa actgcttcat tatgtggtct tggtaaagct gctccaaacc
    96181 ctgttttaag tactcttcaa tattttaaag atgagtatat agctcatgtt gtagataaga
    96241 aatgtcctgc tggtaaatgt cagaacttac tttcttactt tataacagat gactgtaagg
    96301 gttgtacaaa atgttctaga gtgtgtcctg ctggttgtat aacaggttct gttaaggaac
    96361 aacatacaat agatacttct aagtgtctaa aatgtggtgc ttgtatagat aattgtacat
    96421 ttaacgctat aatcaagaaa taacttattt ggaggaggaa taacaatgag tttagttaat
    96481 ttaactatta atggcaaaca cgtttcagca cctagtggaa cttctatctt agatgctgcg
    96541 aaattaataa atataaaaat acacaacctt tgtcatttac atatgaatga aatagataag
    96601 cttgacactt gtgcttcttg tcgtgtttgt atggttgaga cagagagagg attagttcca
    96661 gcttgtggaa cagttataaa ggaaggtatg aaagttcaga ctaatagtgc taaagcatta
    96721 aatgctcgta gaactattgt tgaattattg ttatcagacc atccacaaga ttgttttgtc
    96781 tgtgaaaaaa atggagattg tgaattacag actatagctg ctgatttagg agtaagaaaa
    96841 ataagatatc aaggttccaa atcttttgca ggtaaagata cttctactaa atctttagtt
    96901 aaagaccatt ctaagtgtat attatgtaga agatgtgaga ctgtatgtaa tgacatacaa
    96961 acagtgggag cattatctgg agttaatcgt ggatttaata ctttagttag tacattcttt
    97021 aactctgata tggttgaaac agagtgtaca ttctgtggtc aatgtatatc tgtctgtcca
    97081 actggagcat taacagaagt agataatgta cctaaacttt gggatgtttt aaataaaaaa
    97141 gaaaagacta tagtagtgca agttgctcct gccgtaagag ttgctattgg tgaagagttt
    97201 ggattagaac cagggtcaat ctctacagga aaaatggtag ctgctttaaa agcacttgga
    97261 tttgaacatg tatttgatac aaactttggt gcagatttta ctataatgga agaagctact
    97321 gaatttatag aaagaatcca aaaaggagaa aatcttccta tattaacaag ttgttgtcct
    97381 gcatgggtaa acttcttaga gcacaattat ccagacaagt taaacttagc atctagctgt
    97441 aagtctcctc aaggtatgtt tggttctata gctaaaaact actatgcacc taaaatatta
    97501 ggaatcaatc ctgaagaact ttatgttgta tctgtaatgc cttgtgtagc taaaaaatat
    97561 gaagcttcaa gagaagaatt aagtgaatct ggaatactag atgttgacct ttctataact
    97621 actagagagt tagctaagat gataaaagaa gctgctatcg atttacctaa tcttcaagac
    97681 caagattttg ataatccttt aggaaaatct acaggtgctg catctatatt tggagcaagt
    97741 ggtggagttt tagaagctgc cctacgtact tcatatgaga agataactaa taagacttta
    97801 gataatgtaa acttcactaa tgttagaggt cttaaaggaa ttagggaagc aagtatagat
    97861 gttgatggaa ctacagttaa tgtgtgtatt gtaaatacac ttaaaaacgc tagaaagatt
    97921 atggataagg tcagaagtgg agaatgtaaa taccatatca tagaagttat ggcatgtcct
    97981 ggtggatgtg ttggaggtgc tggtcaacct tatcaccatg gtaatactga aatagttgat
    98041 agacgtgcaa atgcgttata tgaaatagat agaaataagg ctattcgtaa atctcatgag
    98101 aatcctgatt tacaagctat ttataaagac ttctttggag aaccaaatag tgatgtagct
    98161 cataaatacc ttcatactca ttactttgat aagagttgtg tctatggaga gtgtccacaa
    98221 gaatgtgctt gtgaagaagc taagtagtca taacaaagta taaaatttat tcttaaaaaa
    98281 ggattgtctt aaaatacttt tacgtagttt aagacaatcc ttattaattt cacaaattaa
    98341 attatatttc taaatagact tatttattaa ttaacctatc tattaattaa agaatacctg
    98401 ccattctcat aagttgtttt gcatttgtag ttttacatct tccatctttt atcttatagt
    98461 caaaatgaat tttatcgtct acatagtact ctgagaaatg atagtttaca acttcaacat
    98521 ctccgctacc tgaaaggtca catagctcaa aatcatgtgt tgtcaccata cttataaccc
    98581 agggttttga taatttcttt actgcctcac ttgctccaat aattctatca gcagagttag
    98641 ttcccttaaa aatttcatct actagaacca acattggcag ttcttttaaa ctatattgaa
    98701 tcattgattt tattctaaga atctcagcat agaaagttga tattccttga cttacatcat
    98761 cttgtattct catagaagta aatatagcca tacaggtcgc atcaaaactc ttagcgcata
    98821 ctggagcacc tgcatatgcc agcactaagt ttacaccgat acttcttaaa aatgttgtct
    98881 ttccagacat atttgaacct gtgataatac aagtctgaga atttaattgt atcgaatttg
    98941 ctatgacact tttttctgct attaatgggt ggtatacctc ttcaactttc aatcttggag
    99001 tatcttcata ttttattact ggaaaacatg tattttcctt tacatgagaa acaactgtta
    99061 aacttattag agcttcaaat tctccaatag attcaaacca atctctaatt tgatttccat
    99121 atataccttt ccatcgctcc aaagcttctg cacaatgata gttccacatc aaaacaccac
    99181 aggcaattat atatagtatc tgattatacc ttaggtttac agcatttcct attgaattta
    99241 attgtttaac acctcttgaa actccacttc ccttagaaag tttatcttgt aattctttca
    99301 aatatgcact ctcaaacgtc tctttttcta aaacctcaaa cattttttca tatacttgta
    99361 tacttctact aaatgaaaat aatggagcaa gagtttgcat aagtcttgga tatccaaaac
    99421 cactaaaccc taactggatt ataaaaagta aaaaaacagg taaaacaggt aaaaatccta
    99481 acatacaaaa tataaaagat aagattgttg cagttggtaa accccaagta aaaatatgca
    99541 tccattttgg tatatacaca ttcttatttt ctccatactc tataaacgat tctatactaa
    99601 tatctgaatt gtttttttgc tctttaccaa ttatattact gagtgtttga atatgaatag
    99661 aaaaatcatc ttttgataaa agttctttta tagctctctg tctttctaag attacattct
    99721 catctggatt ttcattccac aaatatttgg ctaaaaaatt tttcccataa gatgtattag
    99781 ctacacagat atattgatac aatgatgctc ttccaaataa gtctaaatct tttgcttgcg
    99841 aattttcatc ttttaagtat tctttaccat ctattttaaa ttccttccaa ccatctccaa
    99901 atctcttaat atacttattt aatacttcgc tcttactttt aaaatatgtt tcttcttctt
    99961 ttactttact atgaataact aagagtgcta taaatattat tattgataaa actccaacaa
   100021 aaatacctac tatattttta ttgtaaaatc caatagcaag ccctactatc actatcaaaa
   100081 aagatattaa tcttgctgta cttatgttat ttgacttttt acttaagagc aattcttttt
   100141 cagtactact ttctaaaagt ttactaaaat attctattcc cataaaaaat tccaactttc
   100201 ttgttatata atgaaactca aatataaaat taatctagta ttattataat ctaacactgt
   100261 actttaaatt atccttatat aatatatctt attaataaac attatatata tacaacttga
   100321 ttttaattta taaggtgtag gacataatcc taatcaatat ttaattaaat gatgtgtagt
   100381 ccactattat tcagtactac ttagtatcga ttaattttga taatttttta gtaaattctt
   100441 gagctgcatc gtatcccatt cctctttgtc taaaattcat tgctgctact tctaatatca
   100501 tagcagtatt tcttccaggt ttaacaggta caactaattt ctctacatta acaccaagta
   100561 tttcttcata ttctttatcc agtcccagtc tatcataata cttagtttca tcccaagctt
   100621 ctaaatgaac tactaaatct atcattttag aatttttgat tgcccctact ccatataaac
   100681 ttctaacatc tattattcct attcctctta tctcaagaaa atgtcttatt agttcaggtg
   100741 actgacccac aagcatactt tcatctaatt ttcttatttc tacagcatca tctgcaacta
   100801 atctattacc cctttgaatc agttctaatg ctgtttccga ctttcctata ctactttcac
   100861 cttttatcag tacacctata ccataaatat ctactagcac cccgtgaatt gttgtgtgtg
   100921 gtgctaactt attatccaaa tagtttgaca gtctatttat aagtctagtg gtatttctat
   100981 ttgtgctcaa aagtattctt ttatattttt tagccttttc aattacatct ggcttgattt
   101041 ccaagtctct agaaattatt aacgctggta tttcatatga gaaaaatcta tctagtactt
   101101 cttctcgaat atgactatcc attaatccaa aaaaattata ttctgtcttt ccaactattt
   101161 gtattctttc atatgcaaaa taatcaaaat atcctgcaaa ctgtaatcct ggtctattta
   101221 tatcttgaga gtagacataa taatctacat catcaggcat gtatactact tttaacttca
   101281 actcttttat tatctctctt attgatactt tattgctagt ttccattaat tttcttcctt
   101341 tctaaaaaaa ttataaacat tatctgcaat gcttttattc attccatcta cttctaaaag
   101401 ttcttccata gtagcttttt ttatagcatc tacatcttta aagtgattta ataatgattt
   101461 ctttcttttt tcacctattc cttgtatatc atctaagata gattttgtca aagctttatt
   101521 tcttagactt ctatgatatg ttattgcata attatgaact tcttcttgta tactagcaat
   101581 aaatctatat aaattagttg ttttatctag ttctatttct ttttctttgc atatcaatcc
   101641 tttagttcta tgcttatcat ctttgtacat tccccaaaga ggtatatcta catcattgag
   101701 ttctagtact ttttttactg cactaacttg tccttttcca ccatccaaca atatcaagtc
   101761 aggtaaattt ccatgtttta atcttctatc tacaatttca gccatagaat cataatcatt
   101821 aggtccaata actgtcttta ttttatatct cctatattcc ttcttatctt ttttagcatt
   101881 cgtatacact accatagaac caatcgaatc tacaccttgt atatttgata tatcataagc
   101941 ctctattctt attggcaact tttctagatt taatatttgc tttaattctt ccaatgctcc
   102001 aatacttttt tcatattttc ttttattcat atcagaaaat ttttcaagat attctacagc
   102061 atttttccta accatttcaa ctaagctttt cttctctccc ttttgaggaa ctcttattgt
   102121 tactttttgc ccctttttag atgacagcca ttcttctaat atagaactat cttctatctc
   102181 atcttctata attaattctt taggtatata ctcttgttca ttataaaatt gttttacaaa
   102241 tgaacttaat atagaagctc ttggactatc cattacccct tctaatataa aatgttccct
   102301 acctacaatc ttaccatttc ttataaaaaa tacctggaca caagcttcat tatgagctct
   102361 tgccattgca accacatctt ggtttaagtc acttacagta gcatctattt tttgtttctg
   102421 tatcatctct tcaaggctct ttatcttatc cctatataca gcagcctctt caaatctaaa
   102481 gttcatagaa ctctcattca ttttttcctt taaaagttcc atcaattttt cttctttacc
   102541 agataaacac attataatct cttctatcat ttttccatac tcttctttag aaacatttcc
   102601 tgtacaaggt cctaaacatt tatttatgtg tagatttaaa caaggtcttg tcttattctt
   102661 tattgcttta tctatatcta ttttacagct tcttattgga tacgtactac ttataagctc
   102721 caaggtatca ttcacagcag ttatattggt atagggccca aaatactttg ccttatcttt
   102781 aagaactctt ctaactttta agattcttgg ataatcttca ttcgtagtta cttttatata
   102841 tggataagtt ttatcatctc taagcactac attatacttt ggtctgtatc tttttattaa
   102901 attacattca agtattaatg cctctaactc tgaatccgtt ataatatact caaacttata
   102961 tatattctta accatagatt ttactttaga tgtatggttt tttgaagatt gaaaatactg
   103021 ccttacccta ttttttagag atatggcttt tcccacatat attatatggt cgtatttgtc
   103081 tttcattaaa tatactccgg gctcagaagg taattttttt aaatgctctt gtatatcaaa
   103141 catctcgccc tccaaaacat taaattttat actaaaatta taccctaaaa tatgaatttt
   103201 aaaaagttat acaatttcca gtgctttaga caagttaaag cccatattcc cttctataat
   103261 tgatttgaaa acaattttaa ccatgaagag taatatggac tttactttgt attactattt
   103321 acaacttata tttgactaat ttacttataa caaaacagtt tatcgtatat ctgttctaaa
   103381 atttttcaca atttatataa cttaagaaaa atatttcttt aagaattgac ctgtataaga
   103441 accatcaact ttagatactt cttttggtgt tccagttgca actatagttc cacccttatc
   103501 tccgccttct ggtcctaagt ctattacata atcacaagtc tttataacat ctaaattatg
   103561 ttctatgact ataattgtat ttcctgtatc tgctagtctt tgtaatactt ggattagctt
   103621 gtctacatct gccatatgaa gtccagtagt aggttcatct aatatataca aagtctttcc
   103681 tgttggtctt ttactaagtt cagcagctaa ttttatacgt tgtgcttctc ctcctgataa
   103741 ttgagttgaa ggctgtccta atttaatata tgaaagtcct acatccatta aagtttctaa
   103801 ttttcttttt atatttggta tattttcgaa aaactcaaca gcttcttcca cattcatatc
   103861 taatatatca gatatagttt tatctttgta ttttacttgc aatgtttctc tattgtatct
   103921 ttcaccttta caaatttcac aaggaacata tacatctggt aagaaatgca tttctatttt
   103981 tattattcca tcacccttac aagcttcaca tctaccacct tttacattaa aactaaatct
   104041 acctttttta taacctcttg ctttagcttc attagtagat gcaaaaatat ctcttataaa
   104101 atcaaataca cctgtataag tagcaggatt tgaacgaggt gttcttccaa taggactttg
   104161 gtctatattt ataactttat ctatactttc aattcctttt atctccttat gcttaccagc
   104221 tctttgctta agtctattca ctttacttgc aacacctttg taaagtatat cgtttattaa
   104281 tgtacttttt ccagaacctg aaacacctgt tatgcatgta aacttaccta atgggaactt
   104341 tacatcaata tttttcagat tattttctga tgctttaact atttctataa aacttccatt
   104401 tccttctcta gtagtctcag gaagcaatat ttgtttttta ccacttaaat attgacccgt
   104461 tattgagttc tcattttcaa ttatttcatc taaagtaccc tgtgcaacta tttcaccacc
   104521 atgtatacct gcacctggac caatgtctat aacataatca gcttctctca ttgtgtcttc
   104581 atcatgctct acaacgatta aggtatttcc taaatctgtt agatgtctaa gagtagttat
   104641 aagcctatca ttatctcttt ggtgaagccc tatacttggc tcatcaagta catataaaac
   104701 tccaaccaat gcagaaccta tttgagtagc taatcttata cgttgcgctt ctcctcctga
   104761 taaagttcca gcttttcttg ataaatttaa ataatcaaga cctacatctc ttaagaacat
   104821 agctcttcct tttatctctt ttataatctc atgagctata aacctctgtt tttctgtaag
   104881 atttatattt tccataaagt caatcaattc attcacagat aagtttgtaa cttccattat
   104941 attttttcca tcaactaaaa cagataaaac ttccttttta agtctcatcc ctttacactt
   105001 tggacatggt ctctctgcca tgtattcttc aatcttatct ctcatgtaat ctgaattagt
   105061 ttctctatat cttctctcta agtttactat tacaccttca aagtatgatt tataatttct
   105121 agttcctcca aattttgact cataagtaaa ctctacaatt atattatctt taccataaag
   105181 taattcctcc acaaaatcat ctggtaaatc tttaaacggt gttgtcaaag atacattaaa
   105241 atgctctgct aaacttttta tcattttact gtaataagtg tcatcattaa cacctgttga
   105301 accccatgct gccactgcac cttgttttat tgataaatct ttgtttggta ctactaattc
   105361 tgggtcaact tctttacttt ccccaagacc attacaaaca tcacaagcac caaagggagc
   105421 attaaatgaa aacattcttg gagataattc ttctatgcca attccatgtt ctgggcatgc
   105481 aaatttagtt gaaaaaagaa tttcttctcc atctattatt tgggctatta caagaccatc
   105541 agatagctta actgcagttt caattgaatc tgctagtctt gattctattc catctttaat
   105601 tactattctg tccactacaa cttctatatt atgtttttga tttttattta agattatatc
   105661 atcactaact tcatagtttt caccattaac tctaactctt acaaatcctt cttttttgat
   105721 attatcaaag acttttttat gtgtaccttt ttgtcctcta acaattggtg acagaatttg
   105781 taatttcgtt ctatctggaa aatctagcat tttatcaact atttcttgaa tagtcatctg
   105841 acttattttt tcaccacatg tagggcaata cacatctcct actcttgcaa ataatagtct
   105901 caaataatca tatatttctg ttactgttcc aaccgtagaa cgtgggtttt ttgaggtagt
   105961 cttctggtca attgagatag ctggtgataa accctctata tattctacat ttggcttttc
   106021 catctgacct aaaaattgtc ttgcataagc agatagactt tctacatatc ttctctgccc
   106081 ttctgcatat attgtatcaa atgccaaaga agacttccca gaccctgaca aacctgtaaa
   106141 aacaataaat ttatctcttg gtaattctaa atctatattt tttaaattat gttcttttgc
   106201 tcctcttatt ataattttat cttccataat gttgttttta cctttctatt tttccaattt
   106261 ttcttctaat tgtttcactt tatctctaag ttctgctgct ctttcaaatt gtaagttttg
   106321 agcagcttcc atcatctctg attttaattt atctatatta gctcttattt cgtctttatc
   106381 atctgtatca gatattccat atacaacttc ttcctctgca accttagtag cttctatact
   106441 atctcttata tttttttgta tagttttagg aatgatattg tgctcttcat tatataaatt
   106501 ttgtatatct cttcttctct ttgtttcatc aatagcattt tgcattgagt cagttatcct
   106561 gtctgcatac ataattactc ttccattttc attcctagct gcacgtccaa tagtctgtat
   106621 taaagctgtt tcggaacgta agaaaccttc tttgtctgca tctaaaattg ctataagtga
   106681 aacttctggt atatccaatc cttctctaag taagtttatt cctacaagga catcaaactt
   106741 ccctaatctt aaatctctta ttatttctgt tctttctaat gtaactatat ctgagtgtaa
   106801 atatttaact tttatcccta tttctttaag atagttagtc aaatcctcac tcattttttt
   106861 agttaaagtg gttataagca ctctttcatt tttttctata gttttagtta tttctcctac
   106921 caaatcatct atttgattat ttataggtct tacttctaca attgggtcta aaaggccagt
   106981 tggtcttatt atctgttctg ctattgtctc tgagtgttga atttcataag gtcctggtgt
   107041 agcacttaca aacaacattt gatttatatt tccttcaaat tcttgaaaat ttaatggtct
   107101 attgtcaagt gcagaaggta atctaaaacc attttctata agtgatgttt ttctagacct
   107161 gtctcctgca tacatacctc ttacttgtgg tatagtgaca tgtgcctcat ctacaattat
   107221 caaataatca tctgggaaga aatccattaa agtatatggt ctttctcctt ctgaccttcc
   107281 tgtaatatgt ctagaatagt tctctatccc ctgacaaaat cctatttcct ttaacatttc
   107341 tatatcatac ttagttcttt gttcaattct ttgtgcttct aatagcctat cattttcctt
   107401 gaaaaattta atttgttctt gaagctcgtt ttctatttct acaattgcct tttcaattct
   107461 ttctggcgtt gttacatagt gagatgctgg gaatataaca acatgatttc tagtaccaac
   107521 aatcttccct gttacataat caatttctgt tattctatct acctcatcac caaaaaattc
   107581 tattcttatt gctttttcat cattactagc tgggaatatt tctagtatat ctcctctaac
   107641 tctaaaggta cctcgtgtaa agtttatgtc atttctttcg tattgtatct ctattaacct
   107701 ttttattaca tcatctctgt ctctttgcat acctggtctt atagataaca taagttcttt
   107761 atagtctttt gggtcaccaa gtccatatat acaagataca gatgatatta ttatagtatc
   107821 tcttctctct aaaatagatg ctgtagcaga atgtcgaagt ttatctattt catcatttat
   107881 gcttgcatct ttttctatat aagtgtcact gtgagctaca tatgcttctg gttgataata
   107941 atcatagtaa cttacaaagt attcaactgc attgtctggg aaaaattctt taaactcact
   108001 gtaaagttgt gctgctagag ttttattatg agccattatt agggtaggtt tcttaacttg
   108061 ttgaatgata tttgccattg tgaatgtttt tcctgaaccc gttacaccta ataatgtcga
   108121 aaatttctca tttctattta tagaatccac tattgattta atagcttctg gttggtcacc
   108181 tgtaggtttg aagtctgatt ttattttaaa atccatagta tcactccttt tttcgaacat
   108241 tagttcctga catgtattat tatatcatac ctttataaaa ttgtttaagt tattttaaat
   108301 attttaccca tttaaatttt acttaaatct aaaacataaa aaaagacttc tatctttgca
   108361 atagaagtct ataattcatg gaaaataaat actttattca acttacataa taaaatcaaa
   108421 tgcttctttt tcaactccat ctaattttaa attaaacatt tttaatatag ttgctgcatg
   108481 tgctctcagg tctccttctt ctataaccac accaccttta atatttggtc caaaagctat
   108541 aaatggaggt ctattacctt tagtaggtaa atgaccatgt gtcgcaacag caaacttgta
   108601 atcttttata tctgaatctt ttataatact tccttcgaaa tcatttccaa atgaaattcc
   108661 ttcaagacct tcaattacca tttcaaaatc accttcaaga ccaaggttag atgcttcctc
   108721 tttggtaaaa atattctcta tgaataattc ttctttaaat tcttcaagca gttctcttaa
   108781 ttctgttaac ctatctaagt tatttactat tatttgagct gatattccag aagaatttac
   108841 ataggcatca aaatccttaa cttctccatt ttcaactttt ataaatccat ttgatttaag
   108901 caagacattt ggatttataa ctttatcaac tctaagatga ccatggtccc caagtattat
   108961 aaaatttgta tctttgtatg tacctgcatc ctttgtagcc tgaataatat ctcctagcca
   109021 tttatcattc atttttaatg ctttatctac ttcgtcatta aataagccat aattgtgtcg
   109081 tgtatggtcc aatgtagcta aatgtattag cattaaatct ggtttatatt cctttattat
   109141 atctactgaa cagtttactc caaataaatc catgttgggt tctaatttcc aatcgatata
   109201 atgacaatgt ctattgtaaa taccgtccat tataacctta ctggaacttc gttcaaaagt
   109261 ttctcttggg tcatcttctc tactaggagc ccatatttct gcaatattat aatctatatt
   109321 tggatttgct cccattacag gccataatac actagaggta gttagattat tttcttttgc
   109381 tacatctata atagtttttg cttttatgtc ctttgaatac cagtaccagt ctttattttc
   109441 tttatttggg tcaaattttt cattatgata tataccatgt tttttaggat atactcctgt
   109501 aaccatacta gtatgacacg gatatgtcag agtgggataa acacaattta tattttttac
   109561 tatggagcaa ttttctagta tagatttaaa gtttggtaga ttttttacaa attccaagtc
   109621 tttttcaaat aaagaatcta ctgataatac tataaccttt gtcatttaca ttacctcttc
   109681 atttatatat tattgaatac ttttaatcaa cttacaagtc tatataatta tttatttgtt
   109741 ttatctatta ctgcttgcat tgcagaagtt cctttgctta ctacatcttt tggatttgca
   109801 tttaaatcag taagcccctt tttaatctca tccattagct tatcagttgc ttccttgtat
   109861 ccatttaaca ttggaagtgc aacagcatat tgtaattggt cagttgcaac cttatattga
   109921 ggtttttctt tatataatgt ttgtaacttt tctgagtttg ttgcatcttc agttgttggt
   109981 aagtatcctg ttgatgaact aaactgaacg attttatctg tttgtgtcat ccattctata
   110041 aattctgcac ttgcttcttt ttctttatct gttccacctt caagcataac tagattagct
   110101 ccacctgtag gagttgcgta tttttgattt tttggtaaga atgctgttga tatttcaaac
   110161 ttaccttctg tttgttgcat aagtcctgct aaatctgctg ttgatgtaaa tatcatacct
   110221 actttaccat ttacaaaatc ttgttttgct acgtcccagg cattataatc ttctccagga
   110281 ggcattttca ttattccagc tttcatcata tcttgccaga acttaactgg tgcttgtcct
   110341 gcctcattat taaatgctac ttttttacca ttagttattt ctcctccact ttgcattacc
   110401 atagcttcat agaaccaaat atctattggt gtttcaaaac cataagtatc ttctgattta
   110461 tttgtcattt tactagcata atccttaagc tcttcccatg attttggacc tgaagggtca
   110521 agacctgctt tagttgccat atctttattt atgtataata ttggtgtact tctattaaat
   110581 ggcataccaa caaacttatc ctcataatat gaatttgtta aaagaccaga aaagaatctt
   110641 tcttgatatg ttttatcaaa atatttactc atatctacta aagcacctgc tgatgcgaat
   110701 gtacctgttt gagttatttc taataatgtt acatctggtt ggtctttaga tgttaaggct
   110761 gcctgtagtt ttgttgcatt ttcatagtaa tctttctgtt ttaacatatt tacttgtaca
   110821 tccttatgtt cactattaaa ttggtcaacc attttttgag cagtttctcc attagttcca
   110881 cctaaaggag cccagaaatc tatcttcgta atattgctat cagtcttttc tcctttagat
   110941 gcatttgcat cattagaatt tgaacaccca actaaagaac ctaataataa tgttattgct
   111001 aatcctgttg ctaattttct tttaagcttc attttcatcc tccaaattta gtctttaatt
   111061 ttttatttta ttcctgaata cataaaagct tcttttactt ttttattcgc aaatatataa
   111121 acaagaatta ttggtaaaat tagaattata tttcctgcca ttattacatt ccatgcagta
   111181 attccttctg aagatttaag gagcgcaact cctattggta aagttcttat tgcatctgta
   111241 tttgtcatta ctaagggcca gaaataatta ttccaatggt atataaaatt aaataatata
   111301 aatgttatta ctgctggttt tgccatagga accattattc taaacattat ttttaagtca
   111361 gaagcattat ctagtttagc tgcttcaata atttcatctg aaatctgcat aaaattctgt
   111421 ctaagcagaa atatcccaaa tgaagatgtc ataaatggaa ttataagtgg aacataagta
   111481 tttataaatc caaacttact catcatcata tagactggta gaaaagttac ttgtggtgga
   111541 atcataagtc ctacaagcaa aagcccaaat agcatttttt cacctttaaa tttaatctta
   111601 gaaaatgcat atgctgctgg aaccataact aaaaattgta caattaaaac acttcctgtt
   111661 acaaatacac tgtttagcaa atatctaaaa aatggacctg aatgccatgc tgtactataa
   111721 ttttctaaca ctatatcatt tggtataata gtgggcggta attgcatcat ttcttgtgga
   111781 tttttaaagg atgtagatag catccatata aaagggaata taaatattgc agataaaagt
   111841 aatagaatta atatttctat tgattttgat gctatttttt ttatatcaac tttgtctttt
   111901 ttgataggtt gtataatatc cattgtctcc tccttttgga taaaccttat aatatctact
   111961 ttttctttat tgataatgaa ctttctttga taagagtcta aagttagcat atgtagcaat
   112021 cataactata gctaacaaaa acatactcgc tgcactcgct tgccctatgt catagtatat
   112081 aaatccagac tcatatatat aataagataa catgttagtt gaacccactg gcccaccttg
   112141 tgtcattata cttatctcat caaatacttg aaaagatgca gttgttgttg ttatcataag
   112201 aaaaaatatt gttggtgata atagcggcaa tgtcacttta aagaaattcg ttattttgtt
   112261 tgcattatct aatttagatg cttcatatat atagtttggt atggatttaa gacctgataa
   112321 cactattaag atattgtatc caagagtctt ccatattcct attagaatta gtgacattaa
   112381 agctgaactt tcacttgaaa gccactttga tgttggtaaa tgtaatgtcg atagtatcca
   112441 gtttaaaaag ccatattgtg gctccataat ccaaagccac aatacagcta cagatactag
   112501 tgaaattaca tgtggtgtaa agattatact ttgcgttaaa ttgtgtatta tagaattttt
   112561 atttagccaa acagcaagta ctatggctag tgatatagat atagtcacca taaaaaaagt
   112621 ataaattgca gtgttcgtta tagtttgtat aaactctgga ttctttaaaa gttctgtata
   112681 attgtttaag cctacatttt caaaggttga actaagaaga ctaccagatt tgaagcttaa
   112741 agatatcgtc ttaattattg gatagactat aaacaataaa gttcctataa tagcaggtgt
   112801 tatatataaa tatgctttat taaattgctt tttcataaat atctccttta attttagaat
   112861 acatactttt acatactttt acatcttcta ttctttctcc atttttatca aaataatata
   112921 aatctttttc taatacactt attcttaaag ttcttccaat atcaaatata tcattttccg
   112981 ttttgactct tatctctcta ttaagaacag ataaacaata tatagtttca tttcccaaca
   113041 cttctttagt tacaactttt ccaaatagac taaatacatc atcatttttt ccatctatgt
   113101 ttatactctc tagtgttgct ttttctggtc tgaatccaaa tttaatatca ttttttatat
   113161 ctagtatgtt catacaagga ctccctataa attgagctac aaataaattt ttaggatttt
   113221 gatatatctt ctttggagaa cctatttgca ttatctttcc tttgttcatt ataactatct
   113281 tatctgccat tgacattgcc tcaacctggt catgagttac ataaacaaat gtagacttta
   113341 gtttttgatg taattgtatt aattctgttc tcatttgatt tcttaattta gcatctaaat
   113401 ttgacaatgg ttcatccatt aaaaatacct ttggattttt aaccatagct ctagcaagtg
   113461 ccactctttg tctttgacct ccagataagt tgcctggttt cacatttaaa tattctctca
   113521 atcctactac atcaataact tctgttataa gtttttctct tttttctttt tctacttttt
   113581 tgtttttaag accaaattct atattttctc taacagtcat atgtggatat aatgcataat
   113641 tttgaaatac catagctata tcccttttac tagcatccgt ttttgtaaca tcattttctt
   113701 caatcttcaa cctacctgaa gttatatctt caagacctgc aatcattctt aacgtagtag
   113761 atttaccaca tccacttggg cctaccaata ctgtaaaaga accatcttct atagtaagat
   113821 ttaaattttc tataactgta ttttttttat tataagattt tgttacattt tctagtctta
   113881 tatctgccat ttttatcctc ccaaaatatt taatttaatt ctacgattta cttatagatt
   113941 aataatactc ttaatttgta aaggatatat taagacaaag tgaatatatg gtaaacttat
   114001 taaaataaag gttaaattat aaacattttt tgttaaatat actgaagtta agatgatata
   114061 cagcttatgt tagctataat tttctatatt tttcatattc atggtttgct atcacaatgt
   114121 gattttaatt tatgaagagt catataaaat tatttatttt ttatataatt tggtttgaaa
   114181 ataaaaaaga cctctatggg ggatagaggt ctttaagtgg gggagattga gtaatttatt
   114241 tttgctatat taagttttac aattatatta tgtcccaaat ttacaaggtt taaacataaa
   114301 aaataaaatt tttttaattt ttataaattt accc
//
LOCUS       DAEORM030000004       111695 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.004, whole genome shotgun sequence.
ACCESSION   DAEORM030000004 DAEORM030000000
VERSION     DAEORM030000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 111695)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 111695)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 111695)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..111695
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.004"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            235..1452
                     /gene="ilvA"
                     /locus_tag="KRH23_000410"
     CDS             235..1452
                     /gene="ilvA"
                     /locus_tag="KRH23_000410"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004794 - threonine deaminase activity
                     [Evidence IEA];
                     GO_process: GO:0006567 - threonine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase"
                     /protein_id="HHS5223708.1"
                     /translation="MMNVTLTDVKEARETIKNIVKRTDLLESVKLSEKTGANVFYKCE
                     NLQKTGSFKLRGACNKIASLTDEEKANGVIASSAGNHAQGVALGAKMTGIKSTIVMPA
                     TAPLAKVSATKGYGAEVVLNGAVYDDAYAKAVEIQKETGATFLHPFNDKYVIAGQGTI
                     SLEIFEQLDNKVDTILCPVGGGGIISGVAVAAKALNPNVKIVGVQTANIPSMKESIKN
                     GKVTTAFNDTTIADGIAVKTPGDLTFEIINELVDEIVVVEETEIAESILFMMESQKIV
                     SEGAGAVCTAAILSGKYVPAKDENVVCIISGGNIDINTLYRIIGVALAKEGRRYSFST
                     IMEDKPGNFAELTRIISENGGNILSANQGKLSAGEALGKQSAEFILETIDYDHIARIK
                     KAIEEKGFKIIEL"
     gene            1547..1927
                     /locus_tag="KRH23_000411"
     CDS             1547..1927
                     /locus_tag="KRH23_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HHS5223709.1"
                     /translation="MKHEVIHTNDAPAALGPYSQAIKAGNLLFVSGQVPLVPETMEVV
                     EGDVQAQTAQSLKNLKAILAESGADFSNVVKTTVFIKDMNEFGAINEVYAEYFGENKP
                     ARACVEVARLPKDVKVEIEVIAVL"
     gene            2211..2693
                     /locus_tag="KRH23_000412"
                     /pseudo
     CDS             2211..2693
                     /locus_tag="KRH23_000412"
                     /inference="COORDINATES: protein motif:HMM:NF012578.6"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
     gene            2714..3529
                     /locus_tag="KRH23_000413"
     CDS             2714..3529
                     /locus_tag="KRH23_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HHS5223710.1"
                     /translation="MRVVKIFNNNALSTVTNDRKEAILLGLGIGFNKRPGDKVNEDKI
                     EKIYYVQDHMQTKFLELLKNVSPEVMDASQQIISLIPGNEGKFNNKGILSLVEHISFA
                     IDRMKNNVFLPNLMLLDIKMMYSKEFELGVKALEIIYRVCHIHLPEDEAGYIALHFVN
                     LQSNDNLAYDTLKFVKGSIDLIKECYGLELDESSLSTLRFRTHLKFLAQRIFKNEICQ
                     DDKMIEMYDYLINNHPKNKEYLEKLNVYIEKEFRYKLDKPEKIYLLLHLTKIL"
     gene            3580..5130
                     /locus_tag="KRH23_000414"
     CDS             3580..5130
                     /locus_tag="KRH23_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HHS5223711.1"
                     /translation="MKEKLLGGLETFAKAMVQPLMYLSSAGILMVVGVLLTNDMLLGV
                     LPFFKWEPIQIFGSLIYNCIMAIINNLAVIFAIGIPAALAKKEKHKAALIGFMSYIIY
                     LTASNTMLTSLGQLAKESKMLGLIGTGQATILGIQVVDTSVFGGIILGCIAGYVFNRT
                     SNKTFKGALQIYSGANFSFICMFFVSILIGVVSNFIWPLAQQGIASLANVIKDTGTFG
                     LFLYGFLERILVPTGLHHLIYTPFQFSDLGGVLKVGADTVSGAYAIVMTEMNLPVERF
                     SDSIYYMATGFTKMFGYIGIGAAFIYTAYKQNKKKVKATIIPLIITAVLASVTEPLDF
                     MFVFCAPLLFFVHAVIAGLFIALLKIFDVTALCGGNLLVSIIMNTTVGVEKTHWPVMM
                     ILGLAQIIVYFVVFSFLIKKFNYKTPGREDESTATGEEQSKQLNLDAGIENIIDGLGG
                     KENINTVENCITRLRVNVKDESKINEDIINLTPNSGIVRKGKDIQIIFGLHVHEVRRA
                     VEDFLEAY"
     gene            5227..6579
                     /locus_tag="KRH23_000415"
     CDS             5227..6579
                     /locus_tag="KRH23_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-alpha-glucosidase"
                     /protein_id="HHS5223712.1"
                     /translation="MIITIVGGGSTFTPGIVKSIALREKELELEEIRLFDIDKERQDK
                     VAVVVNWILKEDVKTDVKLTVTNCEKEAYTDATFIFAQMRVGKYEMREQDEKIPLKYG
                     CVGQETCGCGGMAYGLRTIQPMIKVIDDVEKYAKKDYWILNYSNPAAIVSEACRKLRP
                     NARIINICDMPIAIIDMIAGSLNINDVHNIRYDYFGLNHFGWFTSIDYKHRDLIEEIK
                     EYIKENKILLPKSYIENLNKSRSTGNRHAVSSWIHVWESVYTMLESFPKYLPNTYLTY
                     YLLSKETVEHSNINRTRANEVMESREKDLFEGVRHYLETGEISEKAFYAGSHGDWISD
                     LAVSIKNDTRSRFLVITENRGAIPNMPYDAMVEIPAYIGKDGPEVIARGPIPLFQQGL
                     MMQQLNSEKLIVEAYIENSYEKALQAFTLNKTIPSMNVAKEILDEMIEVNKEYWPELR
                     "
     gene            6710..7468
                     /locus_tag="KRH23_000416"
     CDS             6710..7468
                     /locus_tag="KRH23_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HHS5223713.1"
                     /translation="MNIINKIFWEEDRIGMITNNLEADTHSHCMLQLFLGIEDSIEIT
                     VNEKLVKCNCIIVDKNISHSFSARKKVYYSAIIEPTSIYAEQLTSKMNDFGYWICDND
                     GLEKLRQQGTFLIDNSSKEQYLRFMEMLNNYLNIPITLKHYDDRITELLNLLRTCNCD
                     NHTISSFADKVSLSASRLSHLFKEQIGIPLKSYILFHQMECAFRELLSGKNVTEASMT
                     AGFDTPSHFAGTVKRMMGMPVSLSLKDSEFLKVY"
     gene            7515..8234
                     /locus_tag="KRH23_000417"
     CDS             7515..8234
                     /locus_tag="KRH23_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase-like domain-containing protein"
                     /protein_id="HHS5223714.1"
                     /translation="MNKEYLEETKMLNYNEPQLKLLVSSKNWLELDDFHKIKSIYEFV
                     QNDILFGYNASDMLSATQVLNDGMGQCNTKATLLMALLRAVNIPCRLHAFDVTKDFQR
                     GATSKLISLLAPKYILHTWVEVFYQDRWIALEGVITDKKYLEAIQKKFFNHGGTFKKY
                     AIATNDLKNTSIDWDGKDTFIQKEAIVYDYGIFPSPDVFFSTHSQHMSKLKNFIYVHL
                     IRKIMTKNVCKARNNYIDKNE"
     gene            complement(8358..9758)
                     /locus_tag="KRH23_000418"
     CDS             complement(8358..9758)
                     /locus_tag="KRH23_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MDR family MFS transporter"
                     /protein_id="HHS5223715.1"
                     /translation="METQSNNKKGNLIIAIVMTGAFISSLSQTLLSTALPNIMSDFKI
                     TADVGQWLTTIYLLIAGIIVPTTAYLINRFSTRKLFITSMSIFSIGCIIALFSNNFST
                     MLIARVLQAMGSGSLMPLLQVIILYLCPEEKRGAAMSLVGITVGFAPAIGPTLSGWLV
                     DSFGWHSLFLFLSPIAILDVILSFILLRNVGETQKLKLDIPSIVLSSLGFGGLLIGFT
                     NQGNYGWTNIATYLPILIGIMSLILFTLRQLKSKEPFLELRVFKNKPFLISTILIMIV
                     YASMMSATLMIPLYVQSVRGFSALSSGSLMLPGAILMVVLNPIAGRHLDKYGPHALSI
                     LGTGCLFLGTLSFAFLGRDTSLIHVSLMYCIRMIGISMVLMPLTTWGIKTLDRELISH
                     ATAINNTLRQISGAIGSAILITIMTSATKKAHMSSNMLSNIHGIDVAFSIAATLAFTG
                     LIVSICFIKRHQIIRS"
     gene            complement(9762..10652)
                     /locus_tag="KRH23_000419"
     CDS             complement(9762..10652)
                     /locus_tag="KRH23_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HHS5223716.1"
                     /translation="MTEKQRLIITIAQKIFDQKGFQNTSISDVVKECKMSKATFYKHF
                     ETKESFICEIINYYDEKFLEIIHSINENNDIPASEKLNRKIIAVWKNIFSRTTINTYI
                     RENFSEEQRKATSKLQTKSRANLLNEYKLSLFDNYGDKIEKIIFDLVFLLDALIHQFI
                     YIIHVQKREINVYFIAKFTIQILDLVVENMDNLNPLIEKSMFLHKQEDEVYFSLHNKS
                     LFFKTIQDIEELIKTDTSLLENPKLLEAIKKLYVEGKNQQYDSLIMDAMIAYLEKEDT
                     LRPKVLLLNSIKNQLKKETL"
     gene            10931..11578
                     /locus_tag="KRH23_000420"
     CDS             10931..11578
                     /locus_tag="KRH23_000420"
                     /EC_number="3.4.-.-"
                     /EC_number="3.4.17.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004181 - metallocarboxypeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HHS5223717.1"
                     /translation="MKKKICVAIIFALFIVFVEMFIDSSSEGSKIMTAELSKYRKGVN
                     VLSINNIIVANKKYSLPKDYSPQESSEARDAFYKMNKDAQKSGLNLKAFSTYRSYEYQ
                     DRLFKSYVKEHGEKEANRFSAKPGESEHQTGLAFDIGGDDQSCWANQKFNNTKEAKWL
                     YENAYKYGFILRYPEGKENITGYMYESWHYRYVGTEHSKNFAMNNLTLEEYLHIN"
     gene            11903..14542
                     /locus_tag="KRH23_000421"
     CDS             11903..14542
                     /locus_tag="KRH23_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015662 - P-type ion transporter activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0019829 - ATPase-coupled monoatomic cation
                     transmembrane transporter activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HHS5223718.1"
                     /translation="MSYKSTYQEVIKNLDSSLSGLSKERAEELLEKNGANELKEADKV
                     PTYKLFLESFKDPLVIILLIAALVQIFLGETVESIIIFAVIIINSVLGVVQTKKAESS
                     LESLKNLSAPNAKVIRDNKKMTIPAKNLVVGDIVFLEAGDYIPADGRLIEAQSLKVVE
                     GMLTGESEPVLKHTEKISEDVSLGDQKNMVFSGAVVVYGRGSFVVTGTGMDTEMGKIA
                     GLLESAENKLTPLQQKIEDFSKKLGVGIVILALLIFIIQVARNYFMAGNGEMTQIILD
                     SFMFSVAVAVAAIPEALSSIVTIVLAVGTNSMAKKQAIIRKLPAVETLGSTSVICTDK
                     TGTLTQNKMTVVDYYMYGTNNDELDKEKVNYSYHAKLLTMVSTLCNDSHITSDGKEVG
                     DPTEVALINYSSKNDLDYDKLRSKYIRINEIPFDSDRKLMSTVNSIYGDYIMFTKGAP
                     DIVFSRCKYALKNGSKVDITDEIIEEYKHKNEEFSNRALRVLAFAIKDVPEEDFIPSI
                     DDEHDMTLVGIMAMIDPPREEVMDAVKEAKSAGIKTVMITGDHKTTAAAIAKEIGIME
                     EGDLALTGKELDALSEEQLYEKLENISVYARVSPENKIRIVKAWQHKNNITAMTGDGV
                     NDAPALKQADIGIGMGSGTDVAKDASAMVLVDDNFASIVNAVEVGRTVYSNIIKSITY
                     LFAGNLGAIVSIVFAVFAGWSNPFTALQLLFINLVNDSLPAIALGFEKSEKNIMNKPP
                     RHPDESILAGGTLKAVAIRGCIIGVVTIIAQYIGLQVSPELGVAMAFSTLILARIMQT
                     LPARSNNQTVIKLGFFSNKYVIGAVLVCLGLYSLTLIPVLRGIFSIPTTFGLYQLGIC
                     LGLALISSILMELNKLINRSEVK"
     gene            complement(14600..15703)
                     /locus_tag="KRH23_000422"
     CDS             complement(14600..15703)
                     /locus_tag="KRH23_000422"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008483 - transaminase activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HHS5223719.1"
                     /translation="MKLKINKAIEMQLKKSYAIESGHSEDVFEIDCGEGINTVSYSNK
                     AVEAFNALKFDMIRGYPHSIALKDNIVDYWKDFIALDTDRICLADGSIHVIYLLNRLF
                     IEKGDKVLGYSPQFSEYETDIKMHGATYDYVLLKKEDNFKFNEKEFIEKINPEYKVIY
                     IDNPNNPTGQIIPLSSIENIVREAAKYDIAVMVDEAYGEYMPKENSAVKLLNNYDNVI
                     ALKTFSKGFGLAGLRAGYAVLPEQLVSPIKKISTPYEVSEISRSIAANLLDDVQFIEE
                     LKEKTKDIKNQLLIPWKNLNIAETSDTVSIMTVEHKNKDIDLQQEFAKLKIRVISGSD
                     FTGLDKNFIRFRMPEEKELPEVIKAFQIIDNIE"
     gene            16063..16884
                     /locus_tag="KRH23_000423"
     CDS             16063..16884
                     /locus_tag="KRH23_000423"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HHS5223720.1"
                     /translation="MGYKLIVTDMDGTLLGNNHKVTDENKTALQKVIKSGINVTLATG
                     RAFDSAKCNVDFLKEDMPIIACNGSLIREQNGNIIYSNKIDTRTCLNILDVLDKYDIY
                     YQCNSIDSMLSKKIEGREDRLSVFLGSETEVIVKDDLREEIFKKDILKFVIIEEKNPS
                     ILDEIRKELRKVQGIKITSSWPNNIEVMNEGVDKGNAVKILAEKMNIDREDIIAFGDN
                     YNDIEMIKFAGLGVAMGNAEELIKQEADYVTDTNQDSGVAKAIYKFIELKESLSS"
     misc_binding    16963..17174
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            17261..18577
                     /gene="argH"
                     /locus_tag="KRH23_000424"
     CDS             17261..18577
                     /gene="argH"
                     /locus_tag="KRH23_000424"
                     /EC_number="4.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004056 - argininosuccinate lyase activity
                     [Evidence IEA];
                     GO_process: GO:0042450 - L-arginine biosynthetic process
                     via ornithine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HHS5223721.1"
                     /translation="MKLWGGRFRKAENQLMEEFNKSFGYDCVLYKKDIEGSVAHVHMQ
                     VKCGLLTEEEGKSITEGLKGILEDVENGKLVLDGEYEDIHSFTEINLIQRIGDVGKKL
                     HTARSRNDQVAVDMRLYAKEKANDLVDLISEFKATIKDVADKNPVMMPGYTHLQRAQV
                     VTFKHHLMAYYSMFDRDEKRIKNAIEILDESPLGCGALAGTTHDIDRSITCEQLGFKK
                     VVDNFMDGVSDRDYLLELMSDFSIIMMHLSRLSEELILWSSQEFGFVEIDDLYTTGSS
                     IMPQKKNPDGAELIRGKTGRVYGNLFGLFTVMKGIPLAYNKDMQEDKEGFFDSVHTLE
                     MCIQIMDRMIATLKVNEDKMKQAVKNGFLNATEVADYLVKNNVAFRDAHGIVGSIVIY
                     CEDNKKAIEDLTLEELQKFSDAFKEDIYDFIDYESILNKGIKKNLK"
     gene            18826..19164
                     /locus_tag="KRH23_000425"
     CDS             18826..19164
                     /locus_tag="KRH23_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2325 domain-containing protein"
                     /protein_id="HHS5223722.1"
                     /translation="MNLLVIGGHERMEKDYMVMAKKKGYKTKVYTTMSSKLNNSIGRP
                     DAVVILTSTVSHKMSRTVESQAKKQDILIVRHKNSSKVAFNECLDMVDECLGNCSKCK
                     LKDKQKQKNI"
     gene            complement(19291..20580)
                     /locus_tag="KRH23_000426"
     CDS             complement(19291..20580)
                     /locus_tag="KRH23_000426"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase family
                     protein"
                     /protein_id="HHS5223723.1"
                     /translation="MKRNLSLLLICLLIFTSFLGSSNISFADNEPAIVAKHAVLMDYE
                     SGKILYNKDGNSKLYPASTTKVWTACLVLKEVKDLNQVIEIKDLPQIDGSSMYLKNGE
                     SFTVKQLLDALLVHSANDAAFVLARYVGGGNVQKFIDLMNSEAKKIGATNTHFNNPHG
                     LPDPNHYTTAHDMALIAREAMNNDTFRQIVKTKSLKFEATKAYPYERYFVNTNKFLTS
                     HDKITYKGQPINIKYDIVDGIKTGYTDAAGKCLLSSAVKDGRRVIVAVFNSTNADLYL
                     DSRILIDYGFDNFKCATIVDKEKYTDTKKVLFTKQHELIYEPKNSYRIFLEKDESQGN
                     YDTKTELNKIDLPIKKGAKVGTLNVYNNGKLENSIDLIAKNNLDSSLPFLTENNVLMT
                     FVKIIAGILVLLVLFIIASNIKKKKRKKARSKKNMKK"
     gene            20660..21364
                     /locus_tag="KRH23_000427"
     CDS             20660..21364
                     /locus_tag="KRH23_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HHS5223724.1"
                     /translation="MKKKVKFISFFVLFILIISSIIVYKSLIFKDDIYVVSKKNLPNE
                     KTHVVENEIKGEDNNHNKVTKDIDKNFQNNKITIYISGAVNRPGIVTIESDKRLYDAV
                     ELLGGTTKEADLNGVNLSVRLEDEQHYIIPKIGEATSVTSNDDSNKPNQRNESRGEPK
                     NKSNKNISNESKVNINVATIEELDSLPGVGEATANKILQHREENGQFSSIEEIKNVNG
                     IGDKKYENIKDLICVD"
     gene            21456..22502
                     /gene="selD"
                     /locus_tag="KRH23_000428"
     CDS             21456..22502
                     /gene="selD"
                     /locus_tag="KRH23_000428"
                     /EC_number="2.7.9.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015758520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004756 - selenide, water dikinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0001887 - selenium compound metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_except=(pos:21504..21506,aa:Sec)
                     /transl_table=11
                     /product="selenide, water dikinase SelD"
                     /protein_id="HHS5223725.1"
                     /translation="MKKEQKKLTEMTTAGGUAAKIGPEVLASVLSQLPKNDNIENLLV
                     GLDTADDAAVYKLNDDMALIQTLDFFTPMVDDPYVFGQIAASNSLSDVYAMGGKPLVA
                     MNIVCFPSCHDMDVLAEILKGGFDKVKESGALLVGGHTVDDKEPKYGLSVSGIVSPNK
                     VLSNATAKPGDKLIITKPIGVGVLNTAMKEGMVEQHIADKVIEIMIHLNKYAAMSFEK
                     FDVNSVTDITGFGLLGHTLEMAKASEVSIEIESKHVPIIEGAIEMAQMGIIPAGMYKN
                     MHYVSKDVEVVGNIEVAVQDILYDPQTSGGLLISVKEELAEELVKDMKLNGAIEAKII
                     GSVVPKGEKYITVL"
     gene            22553..23932
                     /gene="selA"
                     /locus_tag="KRH23_000429"
     CDS             22553..23932
                     /gene="selA"
                     /locus_tag="KRH23_000429"
                     /EC_number="2.9.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004125 - L-seryl-tRNA(Sec) selenium
                     transferase activity [Evidence IEA];
                     GO_process: GO:0001514 - selenocysteine incorporation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-seryl-tRNA(Sec) selenium transferase"
                     /protein_id="HHS5223726.1"
                     /translation="MLPSVDEVLSDNRIVEIINEYPRSLVLESVREVIDLKRQFILRL
                     KEDASNSVTIEFGEIIESAIERVKLNYSLSLKKVINATGTVIHTNLGRSLLSEDIKDE
                     LWCAASRYSNLEYDLDNGERGSRYSHLTSTIKRLTGAEDVLVVNNNAAAVLLVLSTMA
                     KGGEAIVSRGELVEVGGSFRIPSIMALSGAELVEVGSTNKTHLKDYKEAITEDTNVLM
                     KVHTSNYRIMGFTESVSIEELVNLGKKYKLPVIEDLGSGVFIDLSKYGLSYEPTVLDS
                     IRQGADVVTFSGDKMLGGPQAGIIVGKKEYIEKMKKNQLTRALRVDKLTICALEATLR
                     MYLDETKAIENIPTLKMLTYKIEELEVKANKLFEKITALNLNANINIEDGFSQVGGGS
                     MPLETISTKVISITPEHMNVSSLEKKLRLSEAHIIARVYDNKYVLDVRTIFDDEFDVI
                     VEELRKAFN"
     gene            24046..25929
                     /gene="selB"
                     /locus_tag="KRH23_000430"
     CDS             24046..25929
                     /gene="selB"
                     /locus_tag="KRH23_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0001514 - selenocysteine incorporation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="selenocysteine-specific translation elongation
                     factor"
                     /protein_id="HHS5223727.1"
                     /translation="MKNVVIGTAGHIDHGKTTLIKALTGRETDTLDEEKKRGISINLG
                     FTYFDLPNNRRAGIVDVPGHEKFIKNMLAGASGIDIVLLVVAADEGVMPQTVEHLDIL
                     SFLNIKNGIVVLTKSDTVDDEFRELVKEDICEKIKGTFLEDAEIIEVDSISKRGIDTL
                     IEKIDKMSDDIEDKNENSPARLNIDRVFSIKGFGTVITGTLIEGKISIEDDLVIYPQV
                     LKTKIRSIQVHGENKDTAYAGQRTAINISNVKVDDIKRGDVLAAPNSLEESMMLDVKL
                     SLVNHLDKGLKHWDRLRLYHGTREILCRAVPLDKELIESGESGYVQFRLEESIVSKKG
                     DTFVVRCYSPMETIGGGVIIDPSPKKHKKFDEKVIEALKIKEKGELKDIIEEYLKRNL
                     KNYPNIKEIMSYSGAHEEDVKRALETLISEDKVFIIGNMYMHINQYNKLKENTIKLLS
                     EYHKKYRLRKGILKEEVRSKIESNFKTREMDILLEKLSTENAIKIENNIVSLLDFEVI
                     LNDKQKEIAKKIEKRLKSCGVSSILTIDEVSEGNHNYAEVLESMIGNKVEKLDDLYIM
                     DKDIYENAKNILINYIKENKEITLGEYRDLIDSSRKNCMIILENFDRNKITKRVENKR
                     ILF"
     gene            26034..28772
                     /locus_tag="KRH23_000431"
     CDS             26034..28772
                     /locus_tag="KRH23_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation-associated two-component system
                     sensor histidine kinase"
                     /protein_id="HHS5223728.1"
                     /translation="MKNIIPDVKPDIKEREDMSLLFIIMGSVLLLFIIKDIEKYETLL
                     HAIYTIFLVATGVIIFNTTKFKVDSFSTFLGLIFIATGVLECIYLFNSLGIKTKSIME
                     INITISAITDLFPILGVYLSFKFVKDNKQIYSSVILFIATATLTITSLFIISGICDYL
                     GNGKSQYALGVIISIFIIIISIISGIELNSSSNKGKWEYDEKKIFNRIIVIIILSRVP
                     NLLHIVIDNRNVERILSQIIINVALYYLYNYIVSKNIKKTALELHDTNEELTKKTESL
                     KEKNKKLIYETEKIEELKGILMKRESRLQSTLDVAVNSIVVFSKDGEITYANKSFRNT
                     FGDYKEQDKLTDKIKNFNDLIESIHYVFVHEKNAEKLISTSDNKVYQAIFAPLIIASQ
                     TEGVLCVLEDKTKKKEYERKLIEANKRSKDFLESIGDGIVVLEGNNKIYVNNACREIF
                     KNNLESIDFSLVCKSEESIEKRYVIDGEVKYVEMSFSQYTNAGTNKTIIVIRDTTSRK
                     ISQIKLEESQSSYSRFIDILPDGICLLKEDLSINYANKSFLDMLAFTNIDDIKDSNIK
                     LLMNANTEEKMKFTDNMAKVLNENRSILLLEYELINSYDDIVEVELSALPFAIYNTRY
                     IMLIIKDLVHKKYSEQAEKELLERFKTDKIKTEFFANMSHELKTPLNVISSSNQLVDS
                     FYRNEKIKDYNNNIKSHVDLVRQSSYRLQRLINNIIDLTKMESGFYTLKLAKYNIVSV
                     IEDLFMNIEEYALRKDIKILFDTDLEEINVYIDKVEIERIMLNLLSNCIKFTDNGGWI
                     YVSIHYKIDKVIISVKDTGVGIPQDKLELIFEEFSQVDKTLSRNTEGSGIGLAIVKNL
                     VSLHGGDIEVVSEVNKGTEFLISLPMKGFSSEHYTEDKRIYNIQEKIKIEFSDIYY"
     gene            complement(28891..29835)
                     /gene="manA"
                     /locus_tag="KRH23_000432"
     CDS             complement(28891..29835)
                     /gene="manA"
                     /locus_tag="KRH23_000432"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004476 - mannose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HHS5223729.1"
                     /translation="MEPLFLKPIFMDRIWGGTALKDKFNYEIDSPTTGECWAISSHKN
                     GDCLIENGKYKGKKLSELWNKNRELFGNTPGDKFPLLTKILDANDNLSVQVHPNDEYA
                     KKNENGELGKTECWYVIDCSDDAEIIIGHNAKSHKEFVNMVNNNEWDKLLRKVNIKKG
                     DFFYVPSGTIHAICKGTLILETQQNSDTTYRVYDYDRTDNSGNKRELHVQKSIDVTNV
                     PHINFDTDYKIVSTSDFKCTTFVSNEFFSVYKLDVFGKCNFTHNTPFSLYSVLDGNGK
                     LIHNSVEYNLKKGMHFILPNDFGDFSFEGNLEIICSHI"
     gene            30008..31369
                     /locus_tag="KRH23_000433"
     CDS             30008..31369
                     /locus_tag="KRH23_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HHS5223730.1"
                     /translation="MELFKAESKKYEKEFLKLLEQWVSIPSFYDRKTVSKDMPFGKGV
                     YDALNWFENLGRENNFKVKNIDNHAVQIEYGNGKEYVDIFGHCDVVNPGEGWDSEPFK
                     LNIIGDKLVARGVSDNKGPMIVNFLALKMIKDLDINLKRKVRLIAGGNEESGFKCIKH
                     YYSKEPYGVCGFTPDAKFPVLNGEKGGAIIKLISNIDDKSLYISGGIEFNTIPDKVYI
                     KNVEKLGKDNICFDINNISINYDNGNYIVYGKGGHSSKPEKSINPILATIKLLSENID
                     EKWTKDLYKLINQDNINGNLFGLNIEGKCGILSMVPTIINIVDGKLEVVLSVRYPEIL
                     TIEDIIKKFNLYMEQNNINKFELIGENLKQANYIDRNSKLVRSLHDIYIKYSGDLKND
                     VRVTSAGSYASEMNNSVIFGCEFPDGSFGNVHSANEFASLDRFITAIGIYAEAIITLC
                     NKI"
     gene            31457..33346
                     /locus_tag="KRH23_000434"
     CDS             31457..33346
                     /locus_tag="KRH23_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HHS5223731.1"
                     /translation="MITKKHAIIVKSLSNKDGYMTSNELAIKLDVSTKTIKRYIADLN
                     SVLSKYDLVIASSRGIGYKLSGSKNNIARAIKEANKYIDGFLDDSEESRMSNIICMLI
                     NRNYMSIEAMAEELNLSIAAINKLSSKLKRKLEKYDLVIKSKPYYGSYIHGEEINIRQ
                     LITDYAIKLDEKSKVKVFLDDISENDIHFIESILEKHLREKDTIISDKDFNLLLSKII
                     VSVFRSKRGHSNNINLMDTSYRFHNYYFIENLMKEISDKIGFKLIEDEVIYISNYSGV
                     IAYKGTQGRKNTSEIEERISSVISSALQDIFLISGSDYTKDDEFMVAISDHIKRFLNR
                     ARANVKSNNPLLHQIKEKFPIAFNLAVFLSNKLETEFNLKLDEDELGYIAIHFAASNE
                     RMKKNTSKKICIVCHYGIGTGQLISEKLKQNISDLSVVGVYPVRYLDMAISQDVDLIV
                     STVELKGYEKPVLYIENIFDDSLIENVNKAFYEKEERRKIISNMFDEKAFFSIKANTK
                     EEVIISLSNKLKERDFIEESSIKSIIDRENISSTEIGNLVAIPHTIVKGDKKSIIGVG
                     ILENPIIWDKQEVQLVFMVFFNTKEKHNFSIFKYLYNFIKDEGGVRGIIKICDFNKLM
                     ALIGN"
     gene            33361..33816
                     /locus_tag="KRH23_000435"
     CDS             33361..33816
                     /locus_tag="KRH23_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HHS5223732.1"
                     /translation="MGTNIFNKEYVFLNVDAKSKVEVLKFISKKAKDLNLAEDESVVY
                     EGLMAREEQFTTNLGESIAIPHTKNDAIENPAVVVLKFNEDVVWNEGEDKVKLAISLL
                     MPGKSKENIHLKLLSSLSRKLINKEFKDSLLKSDNVEEISNLINEALGL"
     gene            33875..34192
                     /locus_tag="KRH23_000436"
     CDS             33875..34192
                     /locus_tag="KRH23_000436"
                     /EC_number="2.7.1.202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_function: GO:0022877 -
                     protein-N(PI)-phosphohistidine-fructose phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_function: GO:0090563 - protein-phosphocysteine-sugar
                     phosphotransferase activity [Evidence IEA];
                     GO_function: GO:0090582 -
                     protein-phosphocysteine-D-fructose-phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HHS5223733.1"
                     /translation="MNKKLVALCACPMGLAHTFMAAEAIEQAAKALGYEAKVETQGAD
                     GVQNELTRDDILGATMIIHAVAITPEGMERFDGCEVYEVELQEAIKNAEGVIKEIEED
                     LGI"
     gene            34217..35479
                     /locus_tag="KRH23_000437"
     CDS             34217..35479
                     /locus_tag="KRH23_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HHS5223734.1"
                     /translation="MAIKKKVINSSGASTTGGNNVGKSTPSSPTQSKGNGKWKEISKH
                     IMTGISYMIPVLVMGGLIGALSQLIPYAILGLDPSVGIVDAMNSGEFTGFKLSLLNIA
                     QLMSNFGFTLFGFAIPLFAAFCANSIGGKTALIAGFIGGYIANKPVGVPQFVDGQWTE
                     VVPVASGFLGAILIAFIIGYFVKWLNKSIKVSHNWLAFKTTFLIPLIASLACMVLMIF
                     IITPFGGLINESMKNFLTAAGAAGEYVYATALAAATAFDLGGPINKAAGFVALGLTTE
                     NVLPITARTIAIVVPPIGLGLTTLLDKRLVGRRVYDRQFYQAGKTSIFLSFMGISEGA
                     IPFALERPGFVIPLNIVGSVIGAITGIILGAIQWFPESAIWAWPLVDNLFGYIIGIAV
                     GAIFIAVGNIFYRNKLIKDGKLVVDYID"
     gene            35584..36648
                     /locus_tag="KRH23_000438"
     CDS             35584..36648
                     /locus_tag="KRH23_000438"
                     /EC_number="3.4.11.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004177 - aminopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HHS5223735.1"
                     /translation="MDKIEKVREYFREYDIDGFLINSPTNKFYVGNLFSSSGYVFITK
                     ESQYIIVDFRYFEEIKRKSSLFNVVLMDKTRTHFDIINDICREQNIKEIGFEGNEVSF
                     DLYRSMSNKLSATLKSVDLSTLRETKNEDEIKYIKKACEIVDATFYHIVDFIKVGMTE
                     KQVENEIVRIIKDLGGQKESFDTIVASGLRGALPHGKASEKVIEYGDFVTFDFGAKYN
                     NYCSDITRTICMGTINKELEEIYNIVRKANEECIRVLRPGMTTGEIDKVARDIIGSYG
                     YAGNFGHNLGHGVGIMVHEYPALAPESNEVLKEGMIVTIEPGIYVPSLGGVRIEDDVL
                     ITKDGCMRLTTSTKDLIVVS"
     gene            36702..37880
                     /locus_tag="KRH23_000439"
     CDS             36702..37880
                     /locus_tag="KRH23_000439"
                     /EC_number="4.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0047804 - cysteine-S-conjugate beta-lyase
                     activity [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MalY/PatB family protein"
                     /protein_id="HHS5223736.1"
                     /translation="MYNFDDKPDRVSEKCRKWDLNIIRDKFGDIREDFVPMWIADMDF
                     KIPTEIENKFIEAVRRGVFGYTYCYDEFYDSVIGWQKNMHEVNVEKEWITLTYGTVST
                     LHYVVQAFCKKGDSIILNTPVYDPFESSAKKQGVNVVCNTLDVVNDRYYINFDKLEIQ
                     IKENKPKLMMFCTPHNPSGRIWTIEEMTRVATICKENNVILVADEVHAEHIHYGKFNS
                     ILKIEKELLENVILLTSPNKGFNLGGLKTSYSIVINKDIRDIFRNKLKQNSITSPNVF
                     GIIGLITAYNECREWLSGVNEYIKSNYELLETWVNKYNKIKLMKMESSYLAWMDISGL
                     GISASEFTDKLAIDTGVLLEDGSHFVKDGEKYVRINLGTQKENVIEALNRMDLFLKSL
                     "
     gene            complement(38071..39129)
                     /locus_tag="KRH23_000440"
     CDS             complement(38071..39129)
                     /locus_tag="KRH23_000440"
                     /EC_number="2.7.1.180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0017013 - protein flavinylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HHS5223737.1"
                     /translation="MNKKKITFIFVILILALILFSFFRSSSQNTKYSKTSYYLGTVNE
                     VTVFNVKESKSDKILNECDSILRYIDNKMSTHIPGSDVSKINDNAGKKFVRVSDDTFF
                     VVKEAIQYSKLSDGYFDITIGPLSNLWAIGTDKAKVPSDSEIQKLLPLIDYKNIILDE
                     KNKSIKLTKENMKIDLGAIAKGYAADKIVAYLKSEDVKKGLVNLGGNIFTLENGKNDK
                     PFKIGIQDPTSKNGESIGNIETTNKSVVTSGIYERFIEKDGKIYHHMLNPFTGHPFEN
                     NLSSVTIISDKSINCDALSTSTFGLGLEKGMNLINKIDNVDAIFITKDKKVYLTKGIK
                     DNFKLTDKSFSIEKLNKQ"
     gene            39196..39567
                     /locus_tag="KRH23_000441"
     CDS             39196..39567
                     /locus_tag="KRH23_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HHS5223738.1"
                     /translation="MKKKDILLILGILVVITACYGIINVINSKNAGNIEIYVDNKLYK
                     TVSINAKEEFKIENRGGYNIVKIHDKGVEIVDASCPDKVCVHTGFINKPSQSIVCIPN
                     RVSIKINTNEKNDNQEDIISK"
     gene            39604..40278
                     /locus_tag="KRH23_000442"
     CDS             39604..40278
                     /locus_tag="KRH23_000442"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004844 - uracil DNA N-glycosylase
                     activity [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HHS5223739.1"
                     /translation="MVNLGNDWDELLKEEFEKDYYLNLRKFLIEEYKTRQIFPNMHNI
                     YEALKHTSYKDTKVLILGQDPYHGDNQAHGLAFSVQPQVKTPPSLLNMYKELKDDLGC
                     FIPNNGYLMPWADQGVLLLNTALTVRAHEANSHKNKGWEIFTDRVISILSEREDPVIF
                     VLWGSNARKKVELIDTSKHYILEAPHPSPLSASKGFFGCKHFSKINEILKKLGKEPIN
                     WQIENI"
     gene            40527..41366
                     /locus_tag="KRH23_000443"
     CDS             40527..41366
                     /locus_tag="KRH23_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HHS5223740.1"
                     /translation="MNFKKLSNAKVSVMAVVLSVGILSGYSALNKQVTLVVRGEERTI
                     STFSSNVGDLLESQNISYDSNDIVTLDENTKLSNGDKIEVIDVKEKTVVETKDIPFEV
                     TVVEDGSLLKGDSKVKEEGKSGKSELIYKETYHNGKKVEKEFVKKVVKAEPVNKVVSK
                     GTKVEMQVASSRGESSRRMASSSSSSSSSNNGKNMRVVATAYTGHSITATGTKPKWGT
                     IAVDPKVIPYGTKVYIPQFDMVFTAEDCGGAIKGNKIDIYMNDSKTVYNWGRKTIDIR
                     ILK"
     gene            41610..41706
                     /locus_tag="KRH23_000444"
     tRNA            41610..41706
                     /locus_tag="KRH23_000444"
                     /product="tRNA-Sec"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:41644..41646,aa:Sec,seq:tca)
     gene            41857..42564
                     /locus_tag="KRH23_000445"
     CDS             41857..42564
                     /locus_tag="KRH23_000445"
                     /EC_number="6.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008641 - ubiquitin-like modifier
                     activating enzyme activity [Evidence IEA];
                     GO_function: GO:0061503 - tRNA threonylcarbamoyladenosine
                     dehydratase [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA threonylcarbamoyladenosine dehydratase"
                     /protein_id="HHS5223741.1"
                     /translation="MENNFTTRTSFLVGDDGIKKLNNSNIIVFGVGGVGSFTVEALAR
                     AGVGNITIVDFDDVDITNINRQIPALHSTVGRYKVDVMEERILDINPNINIKKIRSLY
                     NKDTSDEILTERYDYVVDAIDMVSSKIHLIETCEKKGLKIISSMGMGNKLDPTKIVVT
                     DIHKTSTCPLAKVMRKELRDRGIKKLKVVYSTEQPIELKKKVMNGRKVTPGSVSFVPS
                     VGGLIIASVIVNELLGQ"
     gene            complement(42706..43542)
                     /locus_tag="KRH23_000446"
     CDS             complement(42706..43542)
                     /locus_tag="KRH23_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0030420 - establishment of competence for
                     transformation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ComEC/Rec2 family competence protein"
                     /protein_id="HHS5223742.1"
                     /translation="MRNKIFLSILIIISLLIGCDKKSLLSIHMIDVGQGDSILVQTPT
                     NKNILIDGGDEDSENIIISYLRQKRIKTIDIIIATHPDSDHIGSLDNIIKKFNVNSIY
                     MPEQSTDSEAYQNLINSCTDKNLSIQHLYKNDVLNIDNNINIYVLSPSYIQEESNLNS
                     IVFKLTFNDNSFLFMGDAEEENEKEILHSFKLNNINFIKIGHHGSNSSSSLEFIKKIS
                     PDIAAISCGYKNQYGHPHREVINNLKQNHVSIYRTDRIGDIVFYSDGEIIFTKYNYEI
                     DT"
     gene            43730..44635
                     /locus_tag="KRH23_000447"
     CDS             43730..44635
                     /locus_tag="KRH23_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2156 domain-containing protein"
                     /protein_id="HHS5223743.1"
                     /translation="MFFKDIELNSKKELDPYFDLVDYEACEYCFSTLYMWQHVYKTGY
                     YIGEDFAVLVGEYEGDSFSILPLAKKDKLPEVVDFVLEYFSKNNKKIYLRGITTEVVE
                     FLKEKYPGRFEYIEERDLFDYIYDAESLRTLAGKKNQKKRNHINYFLKEYAGRYEAKL
                     LDKENFDECLVLMKEWESNKEENNEFDESMDDELIGIKKIFNHYDILKDKVKVFGVYV
                     DGKLEAFSIGELLNPNMALIHIEKANPDIRGLYPFINQQFLVSEFKDVEFVNREEDLG
                     IEGLRKAKLSYHPCRFVEKYSVREA"
     gene            44644..45828
                     /locus_tag="KRH23_000448"
     CDS             44644..45828
                     /locus_tag="KRH23_000448"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HHS5223744.1"
                     /translation="MEIRYAKEEEIESIKEIWSYCFNDTESFMKYYFNDKYKSENTVV
                     ALDEGKIISSLQLNQYKLLLNSKVYNTSYVVGVSTLPEGRGAGYMNKVMKFTLNELYK
                     KGQLVSILMPIDYRLYRRFGYEHCYDQIEYTINTDDLKNFKSSGKMIKSNLSQIDDLI
                     QIDRTFLNEVNGNVLKDEHYYENLFKEIQSEDGFLYIHEGNEKDGYIVYFLQEDKMFV
                     RELFYKNIDALKSMLKFIYNHNTQCKIVTISTPTIDKIRFILDNPKDSDIKIKPFMMG
                     RVINVKKFIEDIDIENDINSSFNLLIEDKFIDENNGLFKISIQNKKVSVEQLDKKGAE
                     KPQEDFDIKLDINTLTQLSFSYIDVNEAIFLNDIKDVSEETLETLNCIFSKKNNYINE
                     YI"
     gene            45943..47244
                     /locus_tag="KRH23_000449"
     CDS             45943..47244
                     /locus_tag="KRH23_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0030420 - establishment of competence for
                     transformation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ComEC/Rec2 family competence protein"
                     /protein_id="HHS5223745.1"
                     /translation="MGVIIIQIRRPLLIILMFVVAISFIITNNTKNDEELNDKIITIQ
                     GVVKGKIEKKRYNQYKVGVFLINDYTKNKNLKIGQKVNITGKFKSLDKMKYDDFDYGR
                     YIKSTGYKGIVYINNYKIIDKNKRYSLIGEIKFYISKTYRYLYKKNSDFINSILLAEV
                     ENLTEEQKEIFTRTGTSHVISISGLHTGILCVIISFLLRGINKLYKLLILSIFITLYC
                     IMVGASPSIIRSIAFVMIFYLSIFIDRKKDGISALSLIGIILIMNNPYVIYNVSFQLS
                     FLATLSILIFYNKINSIIKLSMVSLTISSNILTLPIIYYTFKGIPLLSIIGNLIIVLF
                     VGVIMYLSIASLIVFKVSVVIAKIISFFNSTLIESIFFLLEKISNLSFAYINIENPKF
                     YIVVIYYIGVFFYIFYIEGKEIKEQENELQGYYKECKREKL"
     gene            47198..48241
                     /gene="holA"
                     /locus_tag="KRH23_000450"
     CDS             47198..48241
                     /gene="holA"
                     /locus_tag="KRH23_000450"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HHS5223746.1"
                     /translation="MNYKDIIRNVKEKNFEKMYLFYGREYYLIENAIKAFKDSLNEGM
                     LDFNLDIIDGKEIVLNQLISSIETLPFMDDRKIVIIKDFELLKGKKKNFTDSDEKYLI
                     EHLDNIPDTTTIVFVVYGDVDKRKSLVKKIGNNGIVFDCDKLSDMDLFKWIKKSFALN
                     DVIIDNSQIMYFIEQEGYRDKSSEKTLSDLENEINKISSFVGKGNNVTNDVIDKLSQK
                     KVENDIFKLIDYIGEQNASNAMKILNDMIQEGESVLGIFSMIARQFKIIMQVRQLQLD
                     GYSTKLIADKLKMHQFVVGKALKQTKNFSDDIIVEILNYILESDYKIKTGLIRDTLAV
                     EMLVSRYCKREAI"
     gene            complement(48428..48694)
                     /gene="rpsT"
                     /locus_tag="KRH23_000451"
     CDS             complement(48428..48694)
                     /gene="rpsT"
                     /locus_tag="KRH23_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HHS5223747.1"
                     /translation="MANIKSAKKRISVIEKKTALNRVRKSQIKTAIRRFEDAVAAGNR
                     EDAVAKFQYAQKRIYQVASKGTIHKNAAARKVAKLAQKLNGMNA"
     gene            49290..49811
                     /locus_tag="KRH23_000452"
     CDS             49290..49811
                     /locus_tag="KRH23_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHS5223748.1"
                     /translation="MDIAKLILNPARLRILQYIRLYGSVRTSDIVKYLNDIPRATVYH
                     HVKILEENNMIEVIKENRVRGTIEKVYALKEYTTSMEGETFVALSTAFYVGLMQEMNE
                     YFSRKEQDHKKDNVFFSSALLYMSDNEYENLLKSIADLLKPYIEQKPKSNLKLRKLSI
                     ISSPPVVDNDKTK"
     gene            49845..50621
                     /locus_tag="KRH23_000453"
     CDS             49845..50621
                     /locus_tag="KRH23_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HHS5223749.1"
                     /translation="MKFHEFGNKNRPHIMLIHGGGNAWWNYLRQAEVLSNKYHVILPT
                     LDGHGEEYETTYISTEDTADKLISYIDENCSGHLFALCGVSLGGQIVMELLSRKPNIT
                     KKAIIDGSICYPRPLMARFCIAGIRFFGGLLFSEKACRFQIAMMPKLLPENMQYPDEI
                     KAYYMTDMPHVRKETFYNMYRTYMMNYTLKENVKKTTAQVMYWYGEKEMKCVKKSAKM
                     FQSHVPSCEIYEAKGYNHGYLSLYLPDEWLTIAETFFHQE"
     gene            50690..51544
                     /locus_tag="KRH23_000454"
     CDS             50690..51544
                     /locus_tag="KRH23_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
                     /protein_id="HHS5223750.1"
                     /translation="MKKSILILAISGIIVSTTSMPVMAEVSDLKYQVNQTDTRTVTQT
                     KGDNKKTNYDPKYPLKGMLEQLGLNTTGKFGWDINYGGNENGHELRADGKYYYINKGY
                     SGLGAYAAAFAGEPYKSIIFKNLDPIKSIAGKELLTYEQAKNELAVIRNFLNSFDWRN
                     ASDMEKANRAAKLVIESKYVSGVAHDTDVYGNIVEKRGSCGSFASSFHVLTRLMGMNS
                     IYQEDGALNHAWNYVQIDGKWYEFDGSEVALYRTSAEFNSSRLENATKTMPKYYDAKA
                     LFALGFNQ"
     gene            51917..52870
                     /gene="gpr"
                     /locus_tag="KRH23_000455"
     CDS             51917..52870
                     /gene="gpr"
                     /locus_tag="KRH23_000455"
                     /EC_number="3.4.24.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004175 - endopeptidase activity [Evidence
                     IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GPR endopeptidase"
                     /protein_id="HHS5223751.1"
                     /translation="MINVRTDLALEASEMCEKSQEGSSIPGVKIETKELENCIVTKVE
                     VIDEQGSEIMNKDIGKYITLESNLMKFDDDESREEMISYLKDELVDIFGQDENKKTLV
                     IGLGNRNITSDALGPKSVSKTLVTRHLFKNYNKDYDDDFTEVSALSPGVMGVTGIETS
                     EIVKSLVEKVKPDRVVAIDALASRKMERVNSTIQISTAGISPGGGVGNTRKSLTKETL
                     GVDVIAIGVPTVVDAATLTIDVLDMAIDNLIAQSEETESFYEMLKKLKEEEKYHLIKD
                     SLDPYDKNLIVTPKDIDDTIENLSIIISEGLNRSLHPGRLV"
     gene            52888..53907
                     /gene="spoIIP"
                     /locus_tag="KRH23_000456"
     CDS             52888..53907
                     /gene="spoIIP"
                     /locus_tag="KRH23_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0061783 - peptidoglycan muralytic activity
                     [Evidence IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein P"
                     /protein_id="HHS5223752.1"
                     /translation="MFKKCIKVVTLTFILVCILPGKSLALNQDDFLKFLVNSSYPEAK
                     VEGNDTENKKNNKNKETSKENKEESKEGNTKSKDASKVDNKKESEKEYIKLYVGKENV
                     PDIESKNSDTTETNTTSSSDYKDDLRVTKENPRILIYHTHGCETYSNSPDGNYHSRDK
                     KNSVMEVGSALTSALDSKGWGVVHTTKYHDYPSYNNSYASSLKTIQSILPKYNSVDIA
                     IDLHRDARDLTNPATKEKDHLKYTTMINGERVSKFFFVVGGKNTNRKQLRALAEDITA
                     FAEKKYPGLVSPIVEKDYARFNQFAVKNHMLVEIGNNATSVEESKATTKYLAEILDEY
                     FKQKN"
     gene            53938..54189
                     /locus_tag="KRH23_000457"
     CDS             53938..54189
                     /locus_tag="KRH23_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5223753.1"
                     /translation="MSRLEKNIESKSKLRKYKCIMRILFLITMIIGTSVCVFIVDSNA
                     KSMLGMKQYDFPSIKFDITKFDFDIPNFDIHEIIKKFNK"
     gene            54471..56276
                     /gene="lepA"
                     /locus_tag="KRH23_000458"
     CDS             54471..56276
                     /gene="lepA"
                     /locus_tag="KRH23_000458"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation elongation factor 4"
                     /protein_id="HHS5223754.1"
                     /translation="MDNKQSRTRNFSIIAHIDHGKSTLADRLIQQTGLVSERDMKSQL
                     LDNMDLERERGITIKLQNIRLMYKAKDGNEYYLNLIDTPGHVDFNYEVSRSLAACEGA
                     LLVVDAAQGVEAQTLANVYLAIDQDLEILPIINKIDLPSARPEEVKNEIEDLIGLDSS
                     EAPLISAKTGLNIEDVLEDIVKNVPPPKGDNEAPLKALIFDSYYDAYKGVVAYVRVFE
                     GTVKKGMTIKMMNTNKKFEVTEVGVMAPGQTELSELSAGDVGYIAASIKDIRSCRVGD
                     TITDSNNPTEEPLPGYKKATPMVYCGIYPGEGEKYENVRDALEKLQVNDAALEYEAET
                     SAALGFGFRCGFLGLLHMEIMQERLEREFNLDIITTAPSVIYRVTKMDGEVVMIQNPA
                     NLPEPSEIKMIEEPIVKGDIIVPKDYVGVVMELCQERRGNMLNMEYIDERRVMLHYDL
                     PLNEVVYDFFDALKSRTRGYGSLDYEVKGYVASTLVKLDILINKEQVDALSFIVHETR
                     AFPRGKAMCEKLKGEIPRHQFAIPIQAAVGNKVIARETISALRKDVLAKCYGGDISRK
                     KKLLEKQKEGKKRMRQIGSVEVPQKAFMSVLKLDE"
     gene            56425..57762
                     /locus_tag="KRH23_000459"
     CDS             56425..57762
                     /locus_tag="KRH23_000459"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0001680 - tRNA 3'-terminal CCA addition
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HHS5223755.1"
                     /translation="MINIEIPKKVDYIIKELEKNGYEAYIVGGCVRDCLLERVPNDWD
                     ITTSARPEVVLELFEKTIPTGIQHGTVTVMIEHEPFEVTTYRIDGNYSDGRHPDSIEF
                     TNNIVKDLSRRDFTINSIAYNSKTGLVDPFNGYEDIQNKYIRCVGNPVDRFEEDALRM
                     LRAVRFSAQLNFKIAEATKQSIHKKADLIKNVSIERIQTEFNKILVSDSSKLNLLKST
                     GLLKFIIPEICELEDVTQHNPYHIYDVQKHTLIATEVIEDELYLKLTMLFHDLGKKVT
                     KTTDKNGVDHFYTHSRESVKIAKKILKRLKYDNYTINKVLILIQYHDYRIEPKRKIIK
                     KLLNKLEDVGLFEDLIKVNWADTLAKNPKYAKQKILNLIECEKEFKHIINQKECFNLK
                     DLAINGKDLISIGIKPGKDIGYILNKMLEIVINNPELNEKEILKEKALNIYTF"
     gene            57995..59308
                     /locus_tag="KRH23_000460"
     CDS             57995..59308
                     /locus_tag="KRH23_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015171 - amino acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HHS5223756.1"
                     /translation="MHTQLQKTIGLSAALSTVVGMVIGSGVFFKPQAIYTTTNGAPGL
                     GIIAWLLGGFITITAGLTATEISAAIPKTGGMMIYIEEIYGEKLGFLTGWMQTVLFFP
                     GTSAALGVIFAQQASELLGMSPNNMANVLPIAIGVILFLALLNIIGSSLGGKVQTVAT
                     IGKMIPLILIIVFGFIKGQSSEVLNPFVGDGVNASNALGQVLIATLFAYDGWINVGAI
                     SGEMKSPEKDLPRAIVGGLSLVMAVYIIINIAYLWVVPASELATVTSPATLVATRLFG
                     NIGGKVITVGILISVFGTLNGYLLTGSRIPYTLAEMGTLPASKTLLKVNSGGSPVNSI
                     LLITVLACVYALSGQFNLLTDLTIFSIWVFYVLTFIGVMRLRRQKPDLHRPYKVPLYP
                     IIPIIAILGGLFVIINQILTSTVISLGGIFITLLGLPVYYYMKKR"
     gene            59480..60655
                     /gene="hemW"
                     /locus_tag="KRH23_000461"
     CDS             59480..60655
                     /gene="hemW"
                     /locus_tag="KRH23_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0051989 - coproporphyrinogen dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM family heme chaperone HemW"
                     /protein_id="HHS5223757.1"
                     /translation="MLGLYVHIPFCVKKCKYCDFNSYKMDIDSKKRYIEDLKIEMELY
                     SNKLYKDNKYKNKECCSLNKNDKITSIFVGGGTPSILTSDEIREVFISIKEMFDIDEN
                     AEITIECNPGTLTLEKLKTMKEIGINRLSIGLQAIQEKHLNFIGRIHTYEEFEKNYKD
                     ALSVGFKNINIDLMYSLPNQTLCDWKETLEKVVHLNPTHISAYSLILEEGTELYNMYE
                     SNKFELIDENVDIEMYEYTINYLKSKGYNQYEISNYSKEGYNCEHNILYWECEHYIGI
                     GAGASGYINENRYNNVESLEDYHLSLVKREKPIQENEILSKKDMIEEKIFMGLRMNKG
                     IKFEDFKKKFGIDFREKYNKQIEMLLARKLINQSFEGIQLTQKGREISNSVFIEFME"
     gene            60758..61777
                     /gene="hrcA"
                     /locus_tag="KRH23_000462"
     CDS             60758..61777
                     /gene="hrcA"
                     /locus_tag="KRH23_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HHS5223758.1"
                     /translation="MELNERKLNILKAIVKDYIETAEAIGSRTISKRHDLGVSAATIR
                     NEMADLEELGYLIQPHTSAGRVPSEKGYKLYVNSLMSKSELDDNDKILIEQCMNHNIN
                     HIKELIHETSKLLSQLTNYTTVAVTKSLINQSVIKHIQLVAMNDNNILLIVVTDKGDL
                     KKANLTTNVYLDQSKLNLISDNLTRKLLGKSITDLDDNLIAFIKYEISEYSGLIDELL
                     NALNSNMKEEDFSLSLNGATNIFSYPEFNDVLKAKSFLNMLEKKETIADIIKSKGIQK
                     DNLNIIIGSDNDCELAQDCSIVTATYNVDRDLVGRISFIGPTRMDYARIYSIINYMSL
                     LINRK"
     gene            61807..62427
                     /gene="grpE"
                     /locus_tag="KRH23_000463"
     CDS             61807..62427
                     /gene="grpE"
                     /locus_tag="KRH23_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000774 - adenyl-nucleotide exchange
                     factor activity [Evidence IEA];
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA];
                     GO_function: GO:0051087 - protein-folding chaperone
                     binding [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HHS5223759.1"
                     /translation="MDKKNEQQEVREENDTSINQESETQVELEEEVVNEECETSSEKT
                     DEKEVDDENVTDINSKLAEKKLQDELDELNDKYQRLQAEYANYRRRTQQEKETIGVFA
                     NEKIITELIPVIDSMERALDACEDKEDTMYKGISLVHKQLIDTLVKFGVEEIEAESKE
                     FDPNLHLAVMQESVDGVEANQIVMVLQKGYKLGTKVVRPSMVKVSC"
     gene            62519..64366
                     /gene="dnaK"
                     /locus_tag="KRH23_000464"
     CDS             62519..64366
                     /gene="dnaK"
                     /locus_tag="KRH23_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HHS5223760.1"
                     /translation="MGKIIGIDLGTTNSCVAVLEGGEAQIIANSEGMRTTPSVVAFTK
                     DGERIVGEPAKRQAVTNADKTITSIKTHMGTDYKVNIDGKSYTPQEISAIILQKLKSD
                     AESYLGQTVTEAVITVPAYFTDAQRQATKDAGRIAGLDVKRIINEPTAAALAYGMDKL
                     DQEKKILVFDLGGGTFDVSILEIGDGTFEVLATAGNNRLGGDDFDQIVIDYLAEEFKK
                     AEGVDLRNDKMALQRLKEAAEKAKKELSSTMSSNINLPFITATAEGPKHLNIDLSRAK
                     FEELTRGLVEKTMEPTKTALQDAGLSTGDIDDVLLVGGSTRIPAVQEAVKKFIGKEPH
                     KGINPDECVAAGASIQAGVLAGDVKDLLLLDVTPLSLGIETMGNVMTKIIERNTTIPT
                     KKSQIFSTAADNQTAVDIHVLQGERSMAYDNTTLGRFQLTDIPPAQRGIPQIEVTFDI
                     DANGIVNVSAKDLGTGKEQKITITSNTNLSEAEIEQKIKEAEMNAEADKQKKEKIEAF
                     NQAESTIYQTEKTLNELGDKISSGEKEDIEKAIADLKAVKDNQDATAEELKKATDEVM
                     TKFQKVSQEMYQKAAQEQQAAQGAEQAQDNGPKDDNVVDADFKEVDEDK"
     gene            64577..65731
                     /gene="dnaJ"
                     /locus_tag="KRH23_000465"
     CDS             64577..65731
                     /gene="dnaJ"
                     /locus_tag="KRH23_000465"
                     /EC_number="1.8.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA];
                     GO_process: GO:0009408 - response to heat [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HHS5223761.1"
                     /translation="MSTKRDYYEVLGISKGAEAQEIKKAYRKLAMKYHPDRNPGDKEA
                     EEKFKEINEAYEVLSDDTKRKTYDQFGHDGLNGQGGFGGQGGFGGQGFGGFEDMFGDI
                     FGDMFGGSFGGGRARRRGPQRGADIRQSVTISFEEAAFGKKMSIKVNRSEECEECNGT
                     GAKPGTSKKTCSTCNGTGQVRTVQRTPFGNIASSRPCSACNGTGEVIESPCSKCHGTG
                     NTRKVKTIEVDIPAGIDDGQMIKLSGQGEVGEKGAPRGDLYIVVNVKSHPLFTRDGND
                     IYFEMPITFVQATLGDEIEVPTLDGKVKYSVPEGTQTGTVFRLKEKGIPRIRGNSRGD
                     QYVKVVVEIPKKLNDKQKELLREFAKECGSNVHEKKKTFGQKIEDMFKKK"
     gene            66697..67632
                     /locus_tag="KRH23_000466"
     CDS             66697..67632
                     /locus_tag="KRH23_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HHS5223762.1"
                     /translation="MYYIGVDIGGTGIQAGVVDNYGKIIFRSECKTVIEKGFEGILND
                     IKIMIYKLLEDNKLTMSDIKSIGFGVPGFINKEGLVTCVNLKWNKKAFNKELKRRFPD
                     VEIHGENDATVAALGEAKFGSMKGANVGVLYTLGTGVGGGIVINQKVFSGAHGLGSEI
                     GHQIIGENYFNCNCGNNGCVETFCSATAIIKYSQKLIEEGEKSRILDLAEGNLENVNA
                     KMVFDAYRENDLVAIKVINRFKEYLAKTFANTINSLDPEIISIGGGISKSSDIILDGI
                     EDLVRKFVLYKTEDIATITCATLGSDAGIIGAAFL"
     gene            67668..69041
                     /locus_tag="KRH23_000467"
     CDS             67668..69041
                     /locus_tag="KRH23_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HHS5223763.1"
                     /translation="MGKTNARRTLFLIAIGSGTMLNPLNSSMISLALHSIQNDFHISF
                     TTVSWIVSAFYLASAIAQPVSGKIGDLIGRKVLFLSGLMLVILSASIVPLVQSFFILI
                     FIRVIQAIGTSTLYPSGVALIQNNIKERQSSALAVLTIFASTTAGLGPTLGGLLLDLG
                     GWHAIFLVNIPVVLVSICLGYFLFPKEVKEKKSIKETLKNVLSRLDIIGILLFSIAMI
                     FILLFLLSMKESFNLEQLVFGIILMCLFIWHELRTKLPFIDIKLFVSNPKLSKVYLQF
                     IILNFFNYILFFGLPSYFQDALHYSAKSTGLFMLFMSGIGIFISPLTGKWIDKSGTRF
                     PLVTSSIFMFISAVLLSVVFIHIPVIGKGIILSLAGISYGVGNVALQSSMFEESPRDS
                     IGTASGLFQTSRYLGSILATVLLGMVFEVNITSEQFQILGYVMVVLGTISFLLNFILK
                     KELRKVE"
     gene            complement(69229..69996)
                     /locus_tag="KRH23_000468"
     CDS             complement(69229..69996)
                     /locus_tag="KRH23_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PucR family transcriptional regulator"
                     /protein_id="HHS5223764.1"
                     /translation="MEELKDFLERQLNKKINIYPYENQKLDASSHLVTFNNAIYVIDF
                     LDKNNLDNLKGNFYLIYQSHIDFEYLKNIFYNLFEDINIIQHNGFFIVNSKYNLDINV
                     TTQNIIETETYQSTYIFYLGELDSKADFDFRLQLCSDLLPHIIKDNAENKFLNLFDLI
                     RYKTLDLINEDNILNKLIDFNKIKSIDEELLYTGIKFINNDLNISKTSTSMFLHRNTL
                     VYRLEKINEILGFDLKNFENAMIFYLSVKSYFLYKKI"
     gene            complement(70026..71135)
                     /locus_tag="KRH23_000469"
     CDS             complement(70026..71135)
                     /locus_tag="KRH23_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHS5223765.1"
                     /translation="MSEVILKNISKLYSNGFNAVKNINIDIKDKEFIVLVGPSGCGKS
                     TTLRMIAGLEEISEGELYIGDKLVNNIEPKDRDIAMVFQNYALYPHLSVYENMAFALK
                     LRKLPKDEIDKKVKEAAKILDLLPLLNKKPKTLSGGQRQRVALGRAIVRNPKVFLMDE
                     PLSNLDAKLRTAMRTEITKLHQQLGTTFIYVTHDQVEAMTMADRIVVMKDGVVQQIAT
                     PQDVYDYPANIFVAGFIGAPQMNFIDVILIEENDEIYAQNEHIKLKLNKEKHYDLIKD
                     NYINNEVVIGIRPEDIHVEDTFIKSNPDTCFKSRIEIKELMGAETYAHLKLGENTITI
                     RFDSKNRINVGDDLTLSVDRSRIHIFDKETTLAIR"
     gene            71393..72130
                     /gene="cas6"
                     /locus_tag="KRH23_000470"
     CDS             71393..72130
                     /gene="cas6"
                     /locus_tag="KRH23_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004521 - RNA endonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0043571 - maintenance of CRISPR repeat
                     elements [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated endoribonuclease Cas6"
                     /protein_id="HHS5223766.1"
                     /translation="MSRISIFMESCNGKFPNENSMLSVSFIKNILNAENKDFAKNIFN
                     YGEERKNNKQIKDINTAIYIPNLIRSKNELLVDGDIIFNISFYNYSMFSKLYNGILKV
                     KELEYKGYRFKIKNIKIHKEHEIKENGVIFKTMSPIIVKNKEGKYLDVEDSNYIECLN
                     YIANLTLESIRGSGLRKPLEFIPINFKKRVLKEKIRGFKVREYYYINAYAGTFFLKGD
                     MEDLNALYKMGIGYRRTENAGMVDILK"
     gene            72135..73610
                     /locus_tag="KRH23_000471"
     CDS             72135..73610
                     /locus_tag="KRH23_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5223767.1"
                     /translation="MREIKAKFYRSGDIVRDIGIVYFYELLMDLKNELEKNDYKLKFT
                     CELNRNYLSLESAEYIDPKYISDYILENQLFKVFKNGKKETLEKIFSNIDNLMYVNFI
                     EELDKSSATAKQKEDIKKDFKNRRFPYVRNSGKYGLNTSLKNMETNVKRIVDTVIKSN
                     IEIDEIDKLDLTQYEEKDSVCNVCNINKTTKLDIDLRERKDSKYNFLFRGAEKSGFKR
                     SGQVESNICFECEFFNLMCLLYINLKRPMVFAYTNDLRELAFLNHKIMLKRKMYSDKS
                     FYKKLLHEKISSIRLYRFDIDTNKGIILKFDSIIEYKELLKKIELIDIIDNYNFSREP
                     GNTRNLGKRMIDNGNLSNLKELLLDNISVLKQSTGTSREMDFVSSSYNIGLYIKLCWI
                     VDGGEEYKMKNYMESNLIYSRVGKDLFNKMTDESRRKNFSMKVIQLLKSNDRTQLFQT
                     IMHVLVSNGILIGEGFVEGLMQSSELELNTNVGLFIQEIMK"
     gene            73630..74643
                     /locus_tag="KRH23_000472"
     CDS             73630..74643
                     /locus_tag="KRH23_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0043571 - maintenance of CRISPR repeat
                     elements [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DevR family CRISPR-associated autoregulator"
                     /protein_id="HHS5223768.1"
                     /translation="MNEKRVKGVTLTILTESPVPLSYDQGYGNYTPIKKEQYREKIHA
                     KTSIATITYDLRRMLHQEYGWNLSNIVFGKKGNIYPSIKKNVGCVDENGLETDVFGYL
                     IPLKDKGSISKASPLRIIPFRSLNPYKGSTQLITNRGFLSSEFGRKYYDEKEENEVPR
                     DENFPTSQALAIEETLSDYYVYTITLELDRIGVVEVEDGKLLLPEERKFMSKELREKA
                     VKDILDAITVFTRNIKHSSVLLKPLAVIGGAFDKVVPFFWDDVDYNADSGEINLEGVI
                     ETIESYSLKESNTILAINDRLKISNKKELNKFNLSKYPVKEIKNLADRLEIGEDNMWY
                     LKE"
     gene            74659..75456
                     /gene="cas5"
                     /locus_tag="KRH23_000473"
     CDS             74659..75456
                     /gene="cas5"
                     /locus_tag="KRH23_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0043571 - maintenance of CRISPR repeat
                     elements [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated protein Cas5"
                     /protein_id="HHS5223769.1"
                     /translation="MKVLQCKLKQPTAHYRDPKVFQNEYISTLNLPSKTTIMGMITYL
                     CDRRLNSDIDIGIIGTHHHRELEFSRGENIDFWNEYTNMRKGKDKEKFLLQGNYYDYY
                     KEHKAQNSILNYEVLKEVELTIFISCKDDEELEFIRKKLESPCKYANLGRKEDFAIPS
                     EKGCFVKEVELKEVIPMNTRDAIKENIKLKNTYVRVDLRDKENVETIINQGVLIALPH
                     KYKDLEANRDDRVYEFCHYIYVDNDGIYPKNIKVNVCIDTKEVFTWL"
     gene            75483..77891
                     /locus_tag="KRH23_000474"
     CDS             75483..77891
                     /locus_tag="KRH23_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated helicase/endonuclease Cas3"
                     /protein_id="HHS5223770.1"
                     /translation="MKNIMQKEILAKSYNLRTNQQEQTLVEHIKDLFEVLESILELNL
                     YSDKDVEILKICCALHDLGKINSIMQQKMEINNKISYSCSEEERKKLESDKKSLKKIA
                     RHNIFSGAFLKDILEKMNLSEEDKLYIYKSIMLHHGNYEDYMRLSISKVQEEIYEYIE
                     KGILEKEEFNLKDIESYINSILNVDFKFGEDVLDYDYIDKLSESMFIDSDYNNGQIDD
                     SVLNYRKFKYILYKGMLNLIDHSASSRQKGIKFYNDFTDEEIDNMILNEIYKSQGNLE
                     KNNIEFNTIQKRLRELSGRNVLTVAFTGSGKTAADYRKTFKRKFFLVPNKISAESFYR
                     KNIFQNKNDLDTRSSNDYIGLLHGDINLYSENEDNGEHDFVLTLRDIDLSINFCKPCV
                     IATVDQLLLSMFKFPGYEKIFAAVKNASITVDEVHLLEPKMFLILIYFMQFACKYLDI
                     DFHLMTATLPKSYKEQMINKGIIFQEESNENVTDKGEIVFIESNKEEEICEGKDVKVS
                     FIKEKEIKSIVEDALENKQKILIIKNTIDSVNRTYEFLKENLSDKYGGVDIDVLHSRF
                     KFKDKKEKYSKILNGEGDIWISTQSVEISLDLDFNIIISDLATMDSLIQRMGRCNRNN
                     KYEYGNFYILPSEDKIYDNKLKNTTKNILKDILKTNSIFTMGIRKTILDDYYDNSVVK
                     KYFEENFISCDKEIKNIYGVNKEIFDGLDLIFNFEPYKNIVDSKKEAAKIFRDVDVSY
                     KIILEEDFYKEDRELQQDSIQVSGFIFNRLYYYGLISKVEGYMVLKSSSKFEYNSTVG
                     LILK"
     gene            78397..79344
                     /gene="prmA"
                     /locus_tag="KRH23_000475"
     CDS             78397..79344
                     /gene="prmA"
                     /locus_tag="KRH23_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HHS5223771.1"
                     /translation="MNNWIEVTIKTTTEAVEPITNILYEQGAGGAVIEDPKDFLFQKK
                     NELDWDYVEEEVFKKNEEDDVLIKTYVSEEKNVMEFVEIIKQKVLGLKDFGIDIGEGS
                     VSLDQVNEADWANAWKAYYKPTKVGQRVVVKPTWEDYAMQEGDLIIELDPGMAFGTGT
                     HETTSMCIRELEKYVNKDSKVFDIGCGSGILAIAAAKLGAKEVVAVDLDEVAVKVAKE
                     NVLENKVEKSVSVMHGNLTDVIKDKADVIVANIIADIIKILAKDVQNFMKEDAIFISS
                     GIILDKVEEVKESLIENGFEIVEVQKLGEWSAIVSKLKK"
     gene            79363..80121
                     /locus_tag="KRH23_000476"
     CDS             79363..80121
                     /locus_tag="KRH23_000476"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HHS5223772.1"
                     /translation="MDRFFVEKNNINLQDKTCTIEGEDVKHISKVLRCKLGEKLEICD
                     KNNNEYICEIMNIDKSIVNLEILEKVDINRESELKVRLYQGLPKAPKMEMILQKLTEV
                     GVEEIILVQTKRSVVKVDDKKEDKKFERWERIIYEAAKQSKRGKIPKLRGVLSFKEAL
                     EDMKKNNVNICPYENERTVSIKHALKKCDSNIDSVGIFIGPEGGFSEEEIEQIQKNNC
                     NVVSLGPRILRTETASVVASTIALYELSDLGGEK"
     gene            80123..81421
                     /gene="mtaB"
                     /locus_tag="KRH23_000477"
     CDS             80123..81421
                     /gene="mtaB"
                     /locus_tag="KRH23_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0035598 - tRNA
                     (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-
                     methylthiotransferase activity [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-
                     methylthiotransferase MtaB"
                     /protein_id="HHS5223773.1"
                     /translation="MKKVAFYTLGCKVNQYETEAMLELFEKDGYEQVNSEEYADVYVI
                     NTCTVTHMSDRKSRQYIRRVKKKNPDAIIAVVGCYSQVSPEEILDIEEVNLVMGTNDR
                     RKIVEEIKNINSSKKVSTVDDIMKVKAFEEIEISQTNGKTRAFMKIQDGCDRFCTYCI
                     IPYARGRVRSRDIDSIVDEVKKLANNGYKEVVLTGIHVASYGKDLKDRDIKLLDVIKQ
                     INQIEKIERIRLSSVEPILFTDEFVNEVLKMDKVCPHYHLSLQSGCDETLKRMNRRYT
                     TLEYKTIVDRLRSKMPDVAITTDVIVGFPGETNEEFKKTYEFLKEIELSQMHIFKYSP
                     RKGTPAATMENQVDPQMKHFRSEQLLNLSKVNFNKFATKFIGRELDVLFEQNIEGNKY
                     EGLTSNYIRVVVESDKNIQGQILKVKINDVKDEYVEGILL"
     gene            81464..81814
                     /locus_tag="KRH23_000478"
     CDS             81464..81814
                     /locus_tag="KRH23_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine triad nucleotide-binding protein"
                     /protein_id="HHS5223774.1"
                     /translation="MDCIFCKIANGEIPSTKVYEDDRVLAFNDLNPVAPYHILVVPKK
                     HYDSLIDIPDKEMDIVSHIHVVINKIAKEKGFDQTGFRVINNCGSDGGQEVKHLHYHI
                     LAGKKLPNYEAGQN"
     gene            81977..82156
                     /gene="rpsU"
                     /locus_tag="KRH23_000479"
     CDS             81977..82156
                     /gene="rpsU"
                     /locus_tag="KRH23_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HHS5223775.1"
                     /translation="MSEVRVRENETLDSALRRFKRQCAMSGIMSEVRKREHYDKPSVK
                     RKKKAEAARRKNAKK"
     gene            82186..82629
                     /locus_tag="KRH23_000480"
     CDS             82186..82629
                     /locus_tag="KRH23_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="HHS5223776.1"
                     /translation="MSLKQKLQEDLKSSMKNKDTVRKSVVTLIRASIKQYEVDNRVEL
                     DEDGIIDVIAKQLKQRRDALVEFEKAGREDLIKETEGEIEVLKEYLPQQLSEEELEEI
                     VKSTISEVGATSMKDMGKIMSVIQPKVKGRADGKLINKLVKQNLQ"
     gene            82740..83237
                     /locus_tag="KRH23_000481"
     CDS             82740..83237
                     /locus_tag="KRH23_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TspO/MBR family protein"
                     /protein_id="HHS5223777.1"
                     /translation="MIISVKEIRNFLINIFIPLIIGYLSSILTMIISGTDISTYYLQL
                     TKPSFAPPAFIFPIVWTILYILMGISSYLILRKGYNLPKVRDAIFYYGLQLVLNFIWS
                     ILFFGFGLRFTALIDIIIMILVSIIMISKFSKIDKRSGYINLIYLMWLVYAGFLNYFI
                     WFINK"
     gene            83430..83993
                     /gene="hpf"
                     /locus_tag="KRH23_000482"
     CDS             83430..83993
                     /gene="hpf"
                     /locus_tag="KRH23_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0045182 - translation regulator activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome hibernation-promoting factor, HPF/YfiA
                     family"
                     /protein_id="HHS5223778.1"
                     /translation="MQIIVSGRQMKLTDGIKGYVDGKLSRLEKYLDPESEVKVTVSAK
                     KDRQKVEVTIIPINGQIIRAEDVEDDLYAAIDIVCDKLSRQVVKYKTKVKDKVQNNKS
                     IRFENLDFIDNSSEFDDYDYDDEEDENIVIERRKKFNVKPMSSEEAILQMELVGHNFY
                     MFRNQDNFEINIVYKRKAGGYGLIEQD"
     gene            84206..84442
                     /locus_tag="KRH23_000483"
     CDS             84206..84442
                     /locus_tag="KRH23_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YabP/YqfC family sporulation protein"
                     /protein_id="HHS5223779.1"
                     /translation="MLEISTDLQVNQPVITVTSNTFISIENYLSILEYEVDLIRIKTK
                     VKTIKISGDKLSLKYITDSEIGIKGIIYNVEYVD"
     gene            84455..85798
                     /gene="yqfD"
                     /locus_tag="KRH23_000484"
     CDS             84455..85798
                     /gene="yqfD"
                     /locus_tag="KRH23_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein YqfD"
                     /protein_id="HHS5223780.1"
                     /translation="MISFIRGYYVIVVEGVGLEQFLNHLIRNGISVYNVTRIKNTKME
                     FHIDRQDIKEFKNVYRGSKFDIKVKQKTGVPFIIKRVYKHKGMWICALVSLFLLMSTS
                     QFVTDVYIQSPEGIKKEALRNELYKVGVRPGVYKKSIDRKEVRDHMMSKFNDVAYLSI
                     NVKGTNIFVTVTKKAESLKSTDQSNYCNVIALKNGIIEKVIPRSGKSVIKSGDIVQKG
                     DVLLNGANTKSIPEVWASTFYESTKKASYVDTVNKKTGEKKNIYTLSFYDKEFTMRKN
                     IKYKDYVVENKEKKLSIGNYTFPIKIKTSTFYETKKVEVKRNKEELKKELSEKALKEL
                     EYIIPASARIIDVKHNFKVNKNMLEYLITVQTSENIAKIYPLSKSEAERFIKEESKPD
                     EGEEEVPSNPEKRPLNDIRNEFDEDNKDNKDQNNSDENNSNQNSNNSQNNNSNNN"
     gene            85737..86852
                     /locus_tag="KRH23_000485"
     CDS             85737..86852
                     /locus_tag="KRH23_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HHS5223781.1"
                     /translation="MKIIVIKIVIIVKIIIAITTNKIKLKILGGLIQLIIQKKFTIAD
                     GNFERELFGNFDENVKLIEKTLNIDVILREGNIILIGEEKNVDSALKLMNELHQTVSN
                     GKHLDKQSISYSLSLLLEGSEQKIKELEGTIVITQRGKTVQPKTLGQKEYIKLIENND
                     ITFGVGPAGTGKTYLAVAMAVKAFKRDEVSRIILTRPAVEAGESLGFLPGDLKDKVDP
                     YLRPLYDALFEMLGADKFNKYLERGTIEVAPLAFMRGRTLDNSFIILDEAQNTTSEQM
                     KMFLTRLGFGSKAVVTGDVTQTDLPQNKKSGLIQATEILKGVPGIGSIMLTDRDVVRH
                     ELVQRIIRAYEKHDKREEFKKEERKKAKMQEKTFKRK"
     gene            86909..87370
                     /gene="ybeY"
                     /locus_tag="KRH23_000486"
     CDS             86909..87370
                     /gene="ybeY"
                     /locus_tag="KRH23_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HHS5223782.1"
                     /translation="MDLILDDRQDKLEVSEELIEKIKDIIIECLDYEGYDDNYEVSLS
                     FVDNKEIHELNREYRGVDRVTDVLSFPLLSDDFEDVELEEESLGDIVVSLERALEQSI
                     EYNHSFEREVCFLICHSMFHLLGYDHDTDENTKEMREKEEHILNKLNITRE"
     gene            87376..88095
                     /locus_tag="KRH23_000487"
     CDS             87376..88095
                     /locus_tag="KRH23_000487"
                     /EC_number="2.7.1.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004143 - ATP-dependent diacylglycerol
                     kinase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006654 - phosphatidic acid biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HHS5223783.1"
                     /translation="MKPEKTRQGIIKAFNAAIEGILYTFKFERNMKIHYLGSVAVLII
                     SLFFNFSKLEMIMLLMSICLVVVAEMFNTAIEKAVDLVTDEYHVLAKIAKDVAAGGVL
                     VAALNSVVVGYILFYDKLTDISGILIYKIRESELHITLICILLVLIAVVVVKALTSTG
                     TPLKGGMPSGHAALAFAIATAITLMTERVVASTLAYIMAVLVAQSRIEGKIHTFWETI
                     AGALLGVLIAILVFQLGMFYN"
     gene            88214..88615
                     /locus_tag="KRH23_000488"
     CDS             88214..88615
                     /locus_tag="KRH23_000488"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004126 - cytidine deaminase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0009972 - cytidine deamination [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HHS5223784.1"
                     /translation="MDNIELLRLAEDARQHSYAPYSGFRVGAALLTKSGKVYTGCNIE
                     CASLGGTNCAERTAIFKAISEGDKDIYKIAIASDNSENNEQTYPCGICRQVIIEFGSD
                     IKIITGYTKGEVFEHSIKDLLPNYFSGNDLK"
     gene            88679..89572
                     /gene="era"
                     /locus_tag="KRH23_000489"
     CDS             88679..89572
                     /gene="era"
                     /locus_tag="KRH23_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HHS5223785.1"
                     /translation="MFKSGFVSIVGRPNVGKSTLMNNVVGEKIAIMSDKPQTTRNTIQ
                     AVYTDEEMQIVFLDTPGIHKPKNKLGEFMVKAATEAFKNVDLILFVVDDSKKIGPGDR
                     KIIEDLRSVKTPIILVVNKIDQLDQKDELFDIIKMYDREGIFKEIVPISALKGKNTDT
                     LIKVIQNYLEEGPKYFPDYMITDQPERVLIAELIREKVLHYLNDEIPHGVAVEIEKMK
                     ARNDKEIVDVSAVIYCERDSHKGIIIGKNGRKLKGIGKSARQDIELLLGSQINLQLWV
                     KVKENWRNLQNYINNFGYNDK"
     gene            89584..90963
                     /gene="mgtE"
                     /locus_tag="KRH23_000490"
     CDS             89584..90963
                     /gene="mgtE"
                     /locus_tag="KRH23_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015095 - magnesium ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015693 - magnesium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HHS5223786.1"
                     /translation="MDRKLDASQDLLYEVKSLIDNNKVLELRELIEEYHIIDIFDIME
                     NLEEDMKIQLFEVLPLDMASSILEEGSVEFFISILSKLDVEHSKNILELMSLGDMADK
                     LSELEEEEREHIINLLNQENADYVKELLFYDEDSAGGTMTTGYISINKDMTALEAIDH
                     MREEAEEAETIYYIYVVDDEEKLVGVLSLRELIIARDANIVEDLMSENIISVYVDEDR
                     EEAVRLVSKYNLIAIPVVDRQEKLKGIITVDDIIDVMEEEATEDMYKFAGSSEHEREV
                     AEKENPTLREQIISALRGRLPWLIITLVGGLLASLILSNLDYIMNPVYAPLVFFIPVV
                     IGMGGNIGTQSSSVTVITLSNKDLNFSNVVREGIVGIITGLLCSIITGIVIYFVMRKL
                     DIVLIVSISLFINMVLGATIGAFMPVLLKKMDADPSTVSSPIISTALDITGIAVYFII
                     TTALLSKIV"
     gene            91036..91191
                     /locus_tag="KRH23_000491"
     CDS             91036..91191
                     /locus_tag="KRH23_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqzL family protein"
                     /protein_id="HHS5223787.1"
                     /translation="MNNISWEVFKKTGSIDAYLYFCDCKNIHEEIEEVREKKEDDDNP
                     EHPGDST"
     gene            91157..91930
                     /gene="recO"
                     /locus_tag="KRH23_000492"
     CDS             91157..91930
                     /gene="recO"
                     /locus_tag="KRH23_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HHS5223788.1"
                     /translation="MIILNTQGIVLKAIRYKESDIILTLFTRKLGKVSAIAKGAKKNK
                     SSLLSSSQLFSYSNFTLKKQGNMYKVTQSEIIKSFYNISYDIEAFSYATYITKLVENS
                     ILENQTNNRLFILLAQTLYLYTQDNTDNRFITAAFELKFLDYIGFKPIVNKCINCECK
                     ILQNSVFNIYEGGILCSKCSKLFDNNIKLDLTTISLMEYVLRNDILTCSKAKVSKYIT
                     HELENILDKYLKVYVDNINFKSLHVLQSVKNNKGVDNDE"
     gene            91923..92522
                     /locus_tag="KRH23_000493"
     CDS             91923..92522
                     /locus_tag="KRH23_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4342 domain-containing protein"
                     /protein_id="HHS5223789.1"
                     /translation="MSSNITIEMVDSVFERVPGATYAEAKEALVMCNGDVIEAVIYLE
                     NKKNTCNCKAKSAKETMEEVFGKDGENIKFQLKELLRKSSVVRIIVEKDGKTMMNIPL
                     TVGVVGLAFVPLATLVGLSAAVISKYRIKVQNEEDGEIVDLGELNEEKLHVLKNMITN
                     AAKDVKDVVVDKKEDDKDVTADLMKEESEKNKEDEDENK"
     gene            92682..93560
                     /gene="glyQ"
                     /locus_tag="KRH23_000494"
     CDS             92682..93560
                     /gene="glyQ"
                     /locus_tag="KRH23_000494"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HHS5223790.1"
                     /translation="MNFQEMILALQKYWSKQGCIMMQPYDIEKGAGTMNPNTFLRSLG
                     PEPWQVCYVEPSRRPADGRYGENPNRLYQHHQFQVILKPSPDNIQELYLESLKEIGID
                     PSEHDIRFVEDNWEAATVGAWGLGWEVWLDGMEITQFTYFQQVGNIECELETGEITYG
                     LERLAMYIQEVDSVYDLKWNDKITYGEVFNKAEYENSMYAFELCDADMLFNLFDIYEK
                     EALRLMENGLVIPSYDYVLKCSHAFNTLDARGAIGVSQRASFIGRVRNMAKTVAETFV
                     KQREEMGFPLLKDGDK"
     gene            93560..95626
                     /gene="glyS"
                     /locus_tag="KRH23_000495"
     CDS             93560..95626
                     /gene="glyS"
                     /locus_tag="KRH23_000495"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HHS5223791.1"
                     /translation="MKNYLLFEIGVEEMPSRFVGSTLEQLKNNLSKLFDENRIAFDKI
                     NAYGTPRRLTLVVEGLSDRQNDLEEEIKGPAKKIAVDAENNLTKPALGFIKSKGLSES
                     DIYFKQVGKEEYIFATIKQDGKETSEVLKDILPETIKSVVFPKAMRWGGKNLKFARPI
                     RWIVALLNDKVLEFDLEGIISSNVTKGHRFLGESTIEVDSIEDYFEKLEKNYIVLDQN
                     KRKEMIRKQCIEVANSLGGEVEFDEDLLEEVTYLVEYPTAFYGEFDVDYIRLPKEVVI
                     TPMKQHQRYFPVLKEGKLLPNFIAVRNGDSYRIDNVKAGNEKVLEARLADALFFYRED
                     TKRNLESYIEKLKTVVFQVKLGTIYDKTLRLEKLSADILDSLGLVDEKADTIRAAKLS
                     KADLVTGMVGEFDELQGFMGKEYAKVGGENDLVSEAIFEHYLPRFAGDILPKTNAGVA
                     LSIADKLDSIAGFFAIGIQPTGSQDPYALRRQALGILSILMDRKVAVDIKVLIEHALD
                     NYSELDFDKEEVVEQIMNFFNERVKNLFKDLGIRYDVVDAVLSSDINDVSDMHMRALE
                     LNNWLEKDELVEMLTAFNRVSTLAQKAESDKIDESLLKEDAEIKLYNEFKQVKIKVNE
                     LLKDKKYGIALDEFASLRPVVDNLFDTVMVMDNDEAIKNNRLALLKQVYDTMLEICDL
                     SKIVYK"
     gene            complement(95792..97339)
                     /locus_tag="KRH23_000496"
     CDS             complement(95792..97339)
                     /locus_tag="KRH23_000496"
                     /EC_number="1.8.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0020037 - heme binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0050311 - sulfite reductase (ferredoxin)
                     activity [Evidence IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitrite/sulfite reductase"
                     /protein_id="HHS5223792.1"
                     /translation="MDNFKKILLNELPNFKEYSSKFLNGEINKMQYKGFSGGYGVYAQ
                     RDKKSFMIRLRVSAGVLSQYQLNKIYEIAIKHNLDKIHLTTRQAIQLHDLSINSIVDI
                     MEEGIKNDIFTRGGGGNYPRNVGLSPLSGVDPSEVFDVTPYAVATDKYFIKNATTYHL
                     PRKLKVSYSNCYTDTAHCSIQDLGFVATLKNDEPYFRVFLGGGLGKQPKVALELDELI
                     KPKDALYCVEGMIKFFMDYGNYENKNRARVRYMVESLGEELFLEKFKEYYKLEKENGS
                     LELNIEEIDYSKPGVKIDIQDSRLIPQKQDGLYTVYIHPVGGILLTKDLSTLLKELDN
                     VENPMIRLGMTEGLYILNLNGNEAKRILEISKTISCNSQLEQSISCIGVPICQMGIQN
                     SQKMLHEIIDYFRLQNNEEILNKAPKLYISGCLNSCGVHQVGSIGLCGKKKNVDGIST
                     DAFELFVGGSFEIGKTRLGKSLGDFKASDIPEMLYKISDASSGNFYEWVNSNDNILNK
                     ITDKYKI"
     gene            97619..98386
                     /locus_tag="KRH23_000497"
     CDS             97619..98386
                     /locus_tag="KRH23_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HHS5223793.1"
                     /translation="MGEIINALDRALDIILLLYHEKREMGITEISKAMGVYKSTVHRT
                     LVTLENKGFVIQNAENGKYWLGINLYAIGMVVGEKMSLTEIVKPYTKKLNQEFNEVVN
                     VSILEERAQDSPRSIIIHKEYGSNQLLSVNPSVGSSSECYCSAVGKCLMAFNDSIDFE
                     KYRKTPIHKYTEHTIDNWDDMMLFLAKIKEQGYAIDDEELEHGLTCIGAPILDKNNKA
                     IAAISLSGPTIRMREGDFEYKIKRVIETAKSISELFR"
     gene            98669..98866
                     /locus_tag="KRH23_000498"
     CDS             98669..98866
                     /locus_tag="KRH23_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HHS5223794.1"
                     /translation="MEKVKLSVERCKGCYLCIEACKKDAISLSDYTNKKGFVTIKVDE
                     EKCIQCGACYTMCPDLVFEIL"
     gene            98895..99971
                     /gene="vorB"
                     /locus_tag="KRH23_000499"
     CDS             98895..99971
                     /gene="vorB"
                     /locus_tag="KRH23_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate dehydrogenase subunit
                     VorB"
                     /protein_id="HHS5223795.1"
                     /translation="MQSLLIKGNEALAEGAIRGGCRFYAGYPITPQSEILEMMAWRQK
                     EVGGVFIQGESEIASVNMVMGASALGARAMTSSSGPGFSLKQEGIAYWVSAGLPAVVA
                     CVQRYGIGDGFIGAGQDNYWQAVKGGGNGDYHLIVLAPNSVQENMDMAYESFELAEKY
                     MHPVLILSDATIGQMVEPCIAPPMKEYDMDKAPWAAKGTPVGEKNKVITDITYFEDQD
                     TWQKGYIEKMRKVQEDEQRWEEIEIEDAEVVFVAYGISSRIAEGAVRDARAKGMKLGL
                     IRPKTLWPYPRKAFKKLSDSLKGLVTVEMNMMAQMKEDVIIACDNRFPVYSVATAQYM
                     AEVNQLIDFAQQIIDGKAKQEEVF"
     gene            99974..100693
                     /locus_tag="KRH23_000500"
     CDS             99974..100693
                     /locus_tag="KRH23_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent enzyme"
                     /protein_id="HHS5223796.1"
                     /translation="MAKKAPAIMMCENMFCGGCGHSIVDRIIGEVLTEMDICQDTIIC
                     SDIGCNHMFQFSMNVDVVVPPHGKMGAAMAAMKRVRPDKYIFTIAGDGGAYAIGLGET
                     MSAATRNDNVIFLVMNNNMFAMTGGQMAPTTIEGQYTASTPAGRNYADHGSTFDVVKV
                     MGNLDIAYLARGTITNPKEINTTKRYIKKALEKQKEKKGFCLIEVLVPCPTNWGLKPV
                     DAMKRIENELVPKYPLGEFID"
     gene            100706..101245
                     /locus_tag="KRH23_000501"
     CDS             100706..101245
                     /locus_tag="KRH23_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016903 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoacid:acceptor oxidoreductase family
                     protein"
                     /protein_id="HHS5223797.1"
                     /translation="MLNEIICAGFGGQGVLTAGKIIMYVAYKAEKKITWFPSYGNEMR
                     GGSANCNVVVSDEKIANPCVKNPDILLGMNSVSVDKYESLMKKNGYMFVNESLVSKDR
                     KYREDINVIKVPVTEIAQNLGNEKAANICMLGAMVKSLDLFTKEEFESGMCEYFENQG
                     KGKFNSKNVEAFEAGYDYE"
     gene            101402..102460
                     /gene="buk"
                     /locus_tag="KRH23_000502"
     CDS             101402..102460
                     /gene="buk"
                     /locus_tag="KRH23_000502"
                     /EC_number="2.7.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0047761 - butyrate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006113 - fermentation [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="butyrate kinase"
                     /protein_id="HHS5223798.1"
                     /translation="MKVLVINPGGTSTKISVFQDENEILKKNITHTREDLKNFSKVFD
                     EYDYRKQLIVDILSSENHSINSFDAVVGRGGLMKAIKGGTYTVSEEMIEDMRNEINGE
                     HASNLGALLAKTIADEIGVQSFVVDPVSVDEFDDVSRITGISDIEKASWLHALNHKAV
                     SRKIAQKLGGKYEDYNFIVAHLGSGISIVAHKQGKMIDGSGGRSDGPFSPERSGGLLA
                     YPLIELCYSGKYTHDEMVAKVSSIGGMYDYLGTKDMIEIENRIKEGDEKAKLIMDAFI
                     YQVAKEISMYGASLSGNVDRVILTGGISHSEMVVKGVAEKVSYLAPIEIVPGEMEMEA
                     LALGALRVLNGEEIAKTY"
     gene            102478..103371
                     /locus_tag="KRH23_000503"
     CDS             102478..103371
                     /locus_tag="KRH23_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional enoyl-CoA hydratase/phosphate
                     acetyltransferase"
                     /protein_id="HHS5223799.1"
                     /translation="MLKDFNNLLEEAKKLEPVIVSVAVAEDKEVLKAVKSATDLNIIK
                     PILVGDKDKIESISREIGLKGHEIIGCQNPDESVKKAVEIVKNKEAKVLMKGLVNTSV
                     YMRAILNKETGLRTGRLLSLLAVYELPQYHKLLYCTDSGINVSPNLNQKKDIMTNALL
                     TMKSIGMENPKTAILTANEMVDPKIQSTVDANLLVEMEKSGEIPKCIVEGPIAFDVAF
                     DAHAAEHKGIKSNIAGDVDLLVFPNIEAGNILGKSWLRFNKAKWAGIVLGATNPIILG
                     SRSDTAEIKINSIALACLASQ"
     gene            103401..104609
                     /locus_tag="KRH23_000504"
     CDS             103401..104609
                     /locus_tag="KRH23_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HHS5223800.1"
                     /translation="MKYAKRMDMVKASAIRDSQKKIAQKVASGGTVISFAAGLPDPNL
                     FPIEEISEITQKVLNERGKFALAYGPTKGEDELLDLLVKRMKEEENIDTKAENIIITT
                     GSQQGIALSAMILLEKGDVVVTENPSYLGAINAFRPYECDFLGVDTDEEGMVTDDLDK
                     LLSENSNIKVIYVIPTFQNPTGKTWSLQRRKDFMEVVNKYDVIVIEDNPYGEIRFTPE
                     PLPTLKSLDTKDKVLYLGSFSKVLCPGFRVAWMCGNVDIIDKAELLKQGIDLQSNQFS
                     QVQVIEFLKKYNLNEHIEKIRAEYKKRCLLMLDAMKKHFPEEAKYTEPDGGMFIWVEL
                     PESINVDDLLDKAIDAGVAYVSGESFFANNGPKNTMRLNYTTMSEEQIVKGVEILAEV
                     IKKELNYACE"
     gene            104633..105892
                     /locus_tag="KRH23_000505"
     CDS             104633..105892
                     /locus_tag="KRH23_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HHS5223801.1"
                     /translation="MGEKENGIKFGKLMFQLVIIAISWELVYIIPFIQYTLYDPILKA
                     LECTNTQLGFLLTIYGLGNIFGAPIGGWLADRFDYRKIILGSVFLNGVVSFLFAFNMN
                     YPFAVATWVGCAITSLVMNYPSMVKILRVIGKDNQGKVYGFNEAMVGVSGVVMGAIFL
                     YIYTCFATPTLGMRWVMISLGILSIAMCPVLWFVIKDVDIKEEREEAGEKMSAGDFIT
                     VLKSPNTWLVGISIFCVYSFTVTMSYFTPYITSVLGGSVALSGALAIIRQHGLKLFGA
                     PFGGYCADKLKSPTKVLLPIYVFGIAVIVLFLVLPASTPMTIFIALTFVVGILGYMGK
                     GIYYAVQDEVKVPVKYSATTIGIAAALGFSPDVFQFALIGHWIDTYGNKGYTYTFIFQ
                     IAILVIGILSCLYILKVKKRRASKLEA"
     gene            106537..108000
                     /locus_tag="KRH23_000506"
     CDS             106537..108000
                     /locus_tag="KRH23_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005283 - amino acid:sodium symporter
                     activity [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine/glycine:cation symporter family protein"
                     /protein_id="HHS5223802.1"
                     /translation="MTDLVNTINGIVWSPVLVAMCLCIGLYFSLKLKFFQIRDVKEMF
                     TLLLEGDSSHVGISSFQGFATSMAGRIGTGNIAGVAVAIAMGGPGALVWMCIMATLGS
                     ATAFVESTLAQIYKDEHDGQYRGGPPYYFEKGLGWKKCSVLFSIVAIISYTFFMPGTQ
                     SNTLYLAMNQAFGFSKMTIAVASSIALAIIIFGGIKRIGLFAEKVVPIMGGAYLIMTL
                     VIIITNISLVPEAIVTMFKSAFGFGSVFGGMLGSAISWGVKRGIYSNEAGEGSGTYGA
                     AAAEVSHPAKQGLVQAFSVYVDTLLICMATGIMIVITGMYNVTGACTALPGVEPGPQY
                     VQSAINTLHPQLGDIFIAIVLLLFTFTTLLAFSYMMETNVSYLVTRIKAEKHEKYIIN
                     VCRFMLIACAAMCCFIEPLTSWALGDICIGVLTYINLIAIFTLKKPAIKAYYDYIRQK
                     KMGIKRSDRTFNPIELDIRNAEFWENRYLKEDKHELN"
     gene            108056..109192
                     /locus_tag="KRH23_000507"
     CDS             108056..109192
                     /locus_tag="KRH23_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HHS5223803.1"
                     /translation="MKERIIQVADSKKEKILGLCQSLYDEPEIALQEYKSAKKISEFL
                     REEGFDVEENLAGMATAFKATKKNGDGPKIAFIAEYDALPGNGHACGHHLIASMGVGA
                     GIALSSILDTYKGEVSIIGTPAEETGDGKPYLIEHGVFDGYDAAMMIHPNSKTCVTPE
                     IIAIGGLDFIFTGKASHAGAKPYNGINALDAVVLLYNNINALRQQLVDGTRIHGIILE
                     AGTAANVIPDMGKVRLEIRAKEQNYFDEVVEKVKNCARGAAIATGCELEFYHFEPTCQ
                     GLNENKVLVDIFTKIMEEFGIYEDEQVMLGSTDMGNLSQIMPCIHPLMKFSENGEELH
                     TKEFLEASINSYAKDRVIDGIKILALTGFNLFENPELLKKMKEE"
     gene            109428..110543
                     /locus_tag="KRH23_000508"
     CDS             109428..110543
                     /locus_tag="KRH23_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C45 family autoproteolytic
                     acyltransferase/hydrolase"
                     /protein_id="HHS5223804.1"
                     /translation="METLEVRNIELSGTNYEIGYRLGELVANMPEILEGQINKSNVVS
                     KKEEKEMIELFDKYCPGLNEELQGFADAIQVNCNQILYYTMTYLKPGCSQVALAPELT
                     ENGHVLFARNFDFSHNMEDFVLCKTKVNGKYAHIGTTVMQFGRGEGMNECGLGVSQSS
                     CGIPVGNSDGLRKPAIVGLQFWAIIRYLLENCKDVDEALEYLKDMPIAYNINLLLADK
                     SGNIALVETLDGKKEVNIINSLESKREYFLHSTNHTHIDKLHKLEPQSMKNSIHRYKL
                     IKEYINKSKKIGEKELMNLLSSKYPNGLSCNYYNDFFGTLKSIVMDLNIGKFNILWGG
                     LENKWESYYLKNDIKSITQRININIEKAPSDFFDFIE"
     gene            110695..111564
                     /locus_tag="KRH23_000509"
     CDS             110695..111564
                     /locus_tag="KRH23_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HHS5223805.1"
                     /translation="MDYLKYFEKAVMYIENNLHENITVNDVAKETGYSYYHLTRLFKS
                     MFGESVGSYIKKRRLVSSTKELLYSDKKVIDIAIGSGFESSEAFSRAFKSIYKVSPIE
                     YRKNRIDVFVGKKKKLELDFMRHLVGNITIKPVIKEIEKIKVIGIKDKVILENNSLPD
                     LWEKFRKVHHIVPNTLPSKRVFGICEAISEIHLVSESMEFNEIIGLEVNSYDVIPNSF
                     VSKTIKEGKYAIFTHTGSLDNLDKTYEYIWGTWFLSSKEELDIRDDFEVYDERFLGPS
                     NVNSQIDIYIPIK"
BASE COUNT        44164 a        11917 c        19771 g        35843 t
ORIGIN      
        1 aagtatatat tattgcttta ataagaatgt gaaaaatatt tttaaattat catttaatgt
       61 aatttaaatg aattgaagat atatgtttat tgtatgcaat tgttgtattt ttaggttttt
      121 tgtgattaat taaaaaatta taaaaatcgt ttacatgttg atttttaaaa aaaaaagata
      181 tagaattata tagaaagtaa taaacaaaaa ttggatttac gggagtggaa tgaaatgatg
      241 aatgttacct taacagatgt gaaagaggct agagagacca ttaagaacat agtaaaaaga
      301 actgacttac ttgaaagtgt taaacttagc gaaaaaacag gagcaaatgt gttctataaa
      361 tgtgagaatc ttcaaaaaac aggttctttt aaattaagag gagcttgtaa caaaatagcg
      421 agtttaacag atgaagaaaa ggcaaatgga gttatagctt caagtgcagg gaatcatgct
      481 caaggagttg cattgggagc aaaaatgact ggtataaaat ctacaatagt aatgccagca
      541 actgcgcctt tagcaaaagt tagtgcaact aaaggctatg gagcagaagt agttttaaat
      601 ggtgcggttt atgatgatgc atatgcaaaa gctgttgaaa tacaaaaaga aacaggagca
      661 actttcttac atccattcaa tgataagtat gttatagcag gacaaggaac tatatctctt
      721 gaaattttcg aacaattaga caataaagtt gatactatac tatgcccagt tggtggagga
      781 ggaatcatct ctggtgttgc tgttgcagca aaagcattaa atcctaatgt aaaaatagtt
      841 ggtgttcaaa ctgcaaatat accttcaatg aaagagtcaa taaaaaatgg aaaagtaaca
      901 acagcattta atgatactac aatagctgat ggtatagctg ttaaaactcc aggagattta
      961 acttttgaaa taataaatga attggttgat gaaatagtag tggttgaaga gacagaaatt
     1021 gcagaatcaa tattatttat gatggaaagt caaaaaatag tttcagaagg tgctggtgct
     1081 gtatgtacag ctgctatatt aagtggtaag tatgtaccag caaaagatga aaatgtagtt
     1141 tgtataatat ctggtggtaa tatagacata aatacgttat atagaataat aggtgttgct
     1201 ttagctaaag aaggaagaag atattcattt agtacaatta tggaagataa gccaggaaac
     1261 tttgctgagt taactagaat aataagtgag aatggtggaa acattttaag tgctaatcaa
     1321 ggtaaattat cagcagggga agctctagga aaacaaagtg cggaatttat attagagaca
     1381 atagattatg accatatagc tagaataaag aaagctatag aagaaaaagg ttttaaaatt
     1441 atagaattat aataaaaagt gtatataata tacaagaaaa atagtataat agtgtatgaa
     1501 gatacatttt atgtgtatta gattaacgaa ttaggaggat tttaaaatga aacatgaagt
     1561 aatacatact aatgatgcac cagcagcttt aggaccatat tctcaagcta taaaagctgg
     1621 aaacttatta tttgtatctg gacaagttcc tcttgtacca gagactatgg aagtagttga
     1681 aggagatgta caagctcaaa ctgctcaatc tttaaaaaat cttaaagcta tattagctga
     1741 aagtggagct gatttttcaa atgtagttaa gactacagta tttataaaag atatgaatga
     1801 atttggggct ataaacgaag tttatgctga atattttgga gaaaataaac cagcaagagc
     1861 ttgtgtagaa gttgctagat taccaaaaga cgttaaagtt gaaatagaag taatagctgt
     1921 attataaaaa tacaatattt ttaatttgaa aaggctgaaa aactatattc tagtgattca
     1981 gcctttttat aaaaaaataa atcacaataa agaacatgat aaatattgtc gaattaaaaa
     2041 ataaaattaa aataaatatt gcaatatttt tgagacggtt ttataatgag tatataattt
     2101 gaaacgtgta actattaaat taggcatgag ttcttggata tttttatcct gaggattcat
     2161 gccttttttg tattgaaatt caaaaatcta tttaataagg aggaagtact gtgttaaatt
     2221 ttttcaagaa aaataaaagc tataagttac atgcagtagt gagtggtaac agcattaata
     2281 ttgagaaagt aaacgattct gtgttttcaa aaaagttaat gggagatgga gttgcaatta
     2341 ttcctaatag taatgttgtt gtagcccctt gtaatggtaa agtaactgtg cttacagaat
     2401 gaaagcatgc ctttggtatg gtctcagatg agggtgttga aatattagtc cacataggaa
     2461 ttgatacagt tagtttacag ggtgaggggt ttaaaaatga agtgtctcaa ggagatactg
     2521 ttaaaaaagg tagtccaata ataagttttg aaagagaaaa aataaattct cagggaattg
     2581 attgtacaac aataataatt gtattaaatc atagcgaatt ttcagaaata aattgcatgg
     2641 tagaaaatga agttgttgca gggcaagata ctgttattga aattatgaaa taataggaag
     2701 ggattaattc aatatgagag tagtaaaaat ctttaataat aatgcattat ctacagtaac
     2761 taatgatagg aaagaagcta ttttactagg tcttggtata ggttttaata aacgtccagg
     2821 agataaagtt aatgaagata aaatagaaaa gatttattat gttcaagacc acatgcaaac
     2881 aaaattttta gaattattaa aaaatgttag tccagaagtg atggatgctt cacaacaaat
     2941 tataagtctt ataccaggaa atgagggaaa atttaataat aaagggatat tatctttagt
     3001 ggaacatatt agttttgcaa tagatagaat gaaaaataat gtttttttac ctaatttaat
     3061 gcttttggat ataaagatga tgtattcaaa agagtttgaa ttaggagtaa aagctttaga
     3121 aattatatat agagtatgtc atatccattt gcctgaagat gaagcaggtt acatagcttt
     3181 acattttgtc aatttacaat caaatgataa tttggcatat gatactttaa aatttgtaaa
     3241 aggtagtatt gatttgatta aagaatgtta tggattagaa ttagacgaat cgagtttaag
     3301 tacattacgt tttagaactc atcttaaatt tcttgctcaa agaattttta agaatgaaat
     3361 ttgtcaggat gataaaatga ttgaaatgta tgattattta attaacaatc atcctaaaaa
     3421 taaagaatat ttagaaaagt taaatgtata tattgaaaag gagtttaggt ataaattaga
     3481 taaacctgaa aaaatttatc tactactaca cctaacaaaa atcttataag aatgagatga
     3541 attagtaata gaaatatata attttagggg gggataagat tgaaagaaaa actacttgga
     3601 ggactggaaa catttgcaaa ggcaatggtt cagccattaa tgtatttatc gagtgcagga
     3661 atattaatgg tggtaggtgt actacttaca aatgatatgt tattaggagt acttccattt
     3721 tttaaatggg agccaattca aatatttgga agcctaattt ataactgtat aatggctatt
     3781 attaataatc ttgctgttat atttgctata ggtattcctg ctgcactagc aaaaaaagag
     3841 aagcacaaag cagcgttaat agggtttatg agttatataa tataccttac agcttctaac
     3901 actatgttaa catcactagg tcaactagca aaagaaagca agatgcttgg actgataggg
     3961 actggacaag ctactatttt aggtattcaa gttgtagaca caagtgtatt tggtggaatt
     4021 attttagggt gtatagctgg atatgtattt aatcgtacaa gcaacaaaac atttaaagga
     4081 gctttacaga tatactcggg agcaaatttt agttttatat gcatgttctt tgtatccatt
     4141 ttaattggag ttgtgagtaa ctttatatgg ccattagctc aacaaggaat agcttctctt
     4201 gcaaatgtca tcaaagatac aggtacattt ggtttattct tatatggttt tttagagaga
     4261 atattagtac caactggact tcatcattta atctatacac catttcagtt ttctgattta
     4321 ggaggagtgc ttaaagttgg tgcagataca gtttcaggag cctatgctat agttatgaca
     4381 gaaatgaatt taccagttga gcgtttctca gatagtatat actacatggc aactggattt
     4441 acaaagatgt ttggttatat aggtatagga gctgccttta tttatactgc atataagcaa
     4501 aataagaaga aggttaaggc aacgattatt ccactaataa ttacggcagt attagcctct
     4561 gtaacagaac cattagactt tatgtttgta ttctgtgcac cacttttatt ctttgtacat
     4621 gcagttatag ctggtctttt tatagcttta ttaaaaatat ttgatgttac tgcattatgt
     4681 ggagggaact tattagtatc aattataatg aatactacag taggcgtaga aaaaacacac
     4741 tggccagtaa tgatgatatt aggacttgca caaattattg tatattttgt agtatttagt
     4801 tttttaatta agaaatttaa ttataaaact ccaggtcgtg aagatgagag tacagctaca
     4861 ggcgaagaac aatcaaaaca acttaattta gatgcaggga tagaaaatat aattgatggg
     4921 ttaggcggaa aagaaaatat taatacagta gaaaattgca tcactagatt acgtgttaat
     4981 gtaaaagatg aaagtaagat taatgaagat ataattaatt taacgccaaa tagcgggatt
     5041 gtaaggaaag gaaaagacat acaaataatt tttggacttc atgtgcatga ggtaagacgt
     5101 gcagtagaag attttttaga agcttattaa agatatatat ttatatagca agggtaaata
     5161 acagctttaa gtgctgttta ctatttatta aagatacata taatttatag aggaggaata
     5221 attattatga ttattactat tgttggtgga ggaagcacat ttactccagg tattgttaag
     5281 tcaattgcat taagagaaaa agagttagag cttgaggaaa ttcgcttatt tgacattgat
     5341 aaagaacgcc aagataaagt agctgtagtt gtcaactgga tactaaaaga agatgttaaa
     5401 acagatgtta aactaactgt aactaattgt gaaaaagaag cgtatacaga tgctacattt
     5461 atatttgcac aaatgcgtgt tggtaaatat gaaatgcgtg agcaggatga aaaaattcca
     5521 ttgaaatatg gttgtgtagg tcaagaaact tgtggttgtg gagggatggc atacggactg
     5581 cgtacaatac aaccaatgat aaaggttatt gatgatgtag agaaatatgc taaaaaagat
     5641 tattggatat taaattactc taatcctgct gcaatcgttt ctgaagcttg tcgtaagtta
     5701 agaccaaatg caaggattat aaatatctgt gatatgccaa tagctattat agatatgata
     5761 gcggggtcat taaatatcaa tgacgttcat aatatacgct atgattattt tggtctaaat
     5821 cattttggct ggtttacttc aatagattat aaacatagag acttaataga agagattaag
     5881 gaatacataa aagaaaataa aatattatta ccaaaatctt atatagaaaa cttaaataaa
     5941 agtcgtagta caggaaatcg ccatgctgta agtagctgga tacatgtttg ggaatctgtt
     6001 tatacaatgt tagaaagctt cccaaaatat ctgccaaaca cttatttaac atactatctt
     6061 ttaagtaaag aaacagtgga acattcaaac ataaatcgta ctcgtgcaaa tgaggttatg
     6121 gaaagccgtg aaaaagactt atttgaaggt gtgagacatt acttagaaac tggagaaatt
     6181 tctgaaaaag cattttatgc aggttcacat ggagattgga ttagtgattt ggcagtttca
     6241 attaaaaatg atacacgtag tcgtttttta gttataactg aaaatcgtgg agctatacca
     6301 aacatgccat atgatgcaat ggtagaaatt ccagcatata ttggtaaaga tggtccagaa
     6361 gttattgctc gaggtccaat acctctattt caacaaggat taatgatgca acaacttaac
     6421 agtgaaaaat tgatagtaga agcttatata gaaaatagtt atgaaaaagc tttacaagca
     6481 ttcacattaa ataaaactat tccaagtatg aatgttgcta aagaaatttt ggatgaaatg
     6541 atagaagtta ataaggaata ctggccagaa ttaagatagt aggataaagg aaagggtttt
     6601 tatttaataa ttagatatgt tttcagagtc ttttatcaaa atgtattcac aaacatatgg
     6661 caatatatta aaataaagag tgatattttt agaagaatgg ggtgatgcaa tgaacattat
     6721 aaataaaatt ttttgggaag aagataggat tggcatgatt acaaataatt tagaggcaga
     6781 tacacatagc cactgtatgt tacaactgtt cttagggata gaagacagca ttgaaataac
     6841 agtcaatgaa aaattagtta aatgtaattg tatcatagta gataaaaata tctctcattc
     6901 attttcagca agaaaaaaag tttattactc tgctattatt gaacctacat ctatatatgc
     6961 agaacagctt acctcaaaaa tgaatgattt tggctactgg atatgtgaca atgatggatt
     7021 agagaaatta cgtcaacaag gaactttttt gatagataac tctagtaaag aacaatattt
     7081 aagatttatg gaaatgctta ataactattt gaatatacct ataactctca aacattatga
     7141 tgacagaatt actgaattgc tcaatttatt acgtacttgt aattgtgata atcatactat
     7201 ttcaagtttt gcagataaag tgtccctatc agcaagtaga ttatcacatc tgtttaaaga
     7261 acaaataggg atacctttaa aaagctatat cttatttcat caaatggagt gtgcttttag
     7321 agaattactt tctgggaaaa atgttaccga agcttctatg actgctggat tcgatactcc
     7381 atcacacttt gcagggaccg ttaagcgaat gatgggaatg cctgtttctt tatctttgaa
     7441 agatagcgaa tttttgaaag tatattaaat attcttgtta tataatgaag ttgtactaag
     7501 aaaggggctt tgttatgaat aaagaatatt tagaggaaac aaaaatgtta aattataatg
     7561 aaccacaact taagcttttg gtatcatcaa agaattggtt ggaattagat gattttcata
     7621 aaataaaatc tatttatgag tttgtacaga atgatatttt atttggatat aatgcttctg
     7681 atatgttaag cgcaacacag gtattaaatg atggtatggg acaatgcaat acaaaagcta
     7741 ctcttttaat ggcattatta cgtgcagtga atatcccttg taggcttcat gcttttgatg
     7801 taacaaaaga ttttcaacga ggagctacat ccaaattgat ttcactatta gcaccaaaat
     7861 atattcttca tacttgggta gaggtatttt atcaagatag gtggattgct ctggagggtg
     7921 tcataactga taaaaaatat ttagaagcaa ttcagaagaa attttttaat catggtggaa
     7981 cgtttaaaaa gtatgcaata gctacaaatg atttgaaaaa tacatctatt gattgggatg
     8041 gtaaagatac ttttatccaa aaagaagcta tcgtgtatga ttatggtatt tttccatcac
     8101 cagacgtatt tttttctact cattcacaac atatgtcaaa attaaaaaat ttcatatatg
     8161 tacatcttat cagaaaaata atgacaaaaa atgtatgtaa ggctagaaac aattatattg
     8221 ataaaaacga atgagtgttt aagaggtaac tatataggaa atatatagaa taattaaaac
     8281 tgtactggtt aaaatgaata aaaaggagtt atcacagagc aaacttaaat tgttcatagg
     8341 ataactcctt ttctgtatta acttctaata atttgatgtc tttttataaa acatatagat
     8401 acaattaaac cagtaaatgc aagagtagct gctattgaaa atgcaacatc tattccatga
     8461 atgttagaca gcatgtttga actcatatga gctttcttag tagcacttgt cattatagta
     8521 ataagtatag cagaacctat agctccagat atctgacgga gtgtgttatt aattgctgtg
     8581 gcatgagata taagttctct atctaatgtt ttaattcccc atgtagttaa tggcattaaa
     8641 accattgaaa taccaatcat acgaatacaa tacatcaatg acacgtgaat taaagatgta
     8701 tctctgccta aaaaagcgaa ggataaagtt cctaaaaaca aacatcctgt tcctaatatt
     8761 gatagagcat gaggtccata tttatctaaa tgacgtcctg caattggatt gagtacaacc
     8821 atcaatatag caccaggtaa cattaatgaa cctgaagata atgcagaaaa tcctcttaca
     8881 gattgaacgt acagaggaat cattaatgta gcagacatca ttgaggcata tacaatcata
     8941 attaatattg tagaaataag aaatggttta tttttaaaaa ccctcaattc taaaaaaggt
     9001 tctttagatt ttaattgacg caatgtaaat aaaattaatg acataattcc tattaatatt
     9061 ggtaaatatg tggcaatatt agtccaccca taattacctt gattagtaaa tccaattaat
     9121 aaaccaccaa aacctagaga tgatagtact attgaaggta tatctaattt tagtttttga
     9181 gtttccccaa catttcttaa tagaataaat gatagtataa catctaatat agcaataggg
     9241 gaaagaaaca gaaataaact atgccaacca aatgaatcta ctaaccatcc tgataaagtt
     9301 ggacctattg ctggagcaaa tcctactgta ataccaacta aactcatagc tgcaccacgt
     9361 ttttcctcag ggcataaata gagtataata acttgtaaaa gtggcattag agaaccagaa
     9421 cccattgcct gcaacacacg agcaatcaac atagttgaaa aattattaga aaaaagtgca
     9481 ataatacatc ctatagaaaa gatagacatt gatgtaataa ataactttct agtactaaat
     9541 cgatttatta aataagctgt tgtgggtaca ataatacctg caataagtag ataaattgtt
     9601 gttaaccact gaccaacatc agcagtaatt ttaaaatctg acattatatt aggtaatgct
     9661 gttgacaata gtgtttgact gagagaactt ataaaagcgc cagtcattac aattgctatt
     9721 attaaatttc cttttttatt gttactttgg gtttccataa tttataacgt ctcctttttt
     9781 aattgatttt taatgctgtt caataaaagt acttttggtc ttaaagtgtc ttctttttct
     9841 aaatatgcaa tcattgcatc cataattaaa gaatcatatt gttgattttt tccctcgacg
     9901 tataattttt ttattgcttc tagtaattta ggattttcaa ggagagaagt atcagttttg
     9961 attagttctt ctatatcttg tatcgtttta aaaaatagcg atttattatg aagggaaaag
    10021 taaacttcat cttcttgttt atgtaaaaac attgattttt caattaaagg atttagatta
    10081 tccatatttt ctacaactaa atctagaatt tgtatagtaa atttggcaat aaagtataca
    10141 tttatttctc ttttttgtac atgaataatg tatataaact gatgaattag agcatccaat
    10201 aagaaaacta aatcaaatat aattttttct attttatcac catagttatc aaataagctt
    10261 aatttgtatt cattcaataa gttagctcgt gattttgttt gcaatttact tgtagcctta
    10321 cgttgctctt cagaaaaatt ttctcttata taggtattta tggtagttct agaaaaaata
    10381 tttttccata cagcaattat ctttctgttt aacttttctg atgctggaat gtcattattt
    10441 tcatttatgg aatgtataat ttctaaaaac ttttcatcat aataattgat tatttcgcag
    10501 ataaaacttt ccttagtttc aaaatgcttg taaaaagtag ctttagacat tttacactct
    10561 tttacaacat ccgatattga agtattttga aaaccctttt ggtcaaaaat tttttgtgca
    10621 atagttataa tgagcctttg tttttctgtc actttattat ctcctttcac gcaaaaacgt
    10681 ttagtactat atagtaccta caagttttaa taaatatatt atacatcatt tggaaaaaaa
    10741 atcaatatat agactgtaat atgaaatttt tgaaaaattt gttgttattt ttagtcgtat
    10801 aaaaaagaaa cttaagagtt tcttaagaat tgtttaaaga agttgcaata aattagtggt
    10861 atgattatag tatgaaagag aatgtcttga aatttttctg tatcaaattc caattatgga
    10921 ggtgtagtat atgaaaaaga aaatttgtgt agcaataatt tttgctctat ttatagtttt
    10981 tgtagaaatg tttattgata gctctagcga aggaagtaaa attatgacag ctgaattaag
    11041 taaatacagg aaaggcgtaa atgtattatc aataaacaat attatagtag cgaataaaaa
    11101 atatagtttg cccaaagatt attctcctca ggaaagcagt gaagcgagag atgcttttta
    11161 taaaatgaat aaagatgctc aaaagtcagg attaaattta aaagctttta gtacatatag
    11221 aagttatgaa tatcaagata gattatttaa gtcatatgta aaagaacatg gagaaaaaga
    11281 agcaaataga ttttcagcta aacctggaga gagtgagcat caaactggac ttgcttttga
    11341 tattggagga gatgaccagt cttgttgggc aaatcaaaag ttcaacaata caaaagaagc
    11401 taagtggttg tatgaaaatg catataaata tggttttata cttagatatc cagaaggtaa
    11461 agagaatata acaggatata tgtatgaatc ttggcactat agatatgttg gaactgaaca
    11521 tagcaaaaac tttgcaatga ataatttgac tttagaagaa tatttacata taaattaaga
    11581 gatggtttgt taaaattagg ttaaaataaa aaataaccta gactattagc tgtgtaaagt
    11641 gatataatgt aaatacaatt taagataact actcgaaggg gagtagctta cacgaaagtg
    11701 gtaattaatc gtcaagacag tagaaatact cggttaatta gcaagggatt ccttgatagc
    11761 aagaccttca aaataagcat taggtatgtt tgttttgggg tcttttttta ttcaaggaat
    11821 ttttatttaa aaaaatttaa atttcaagta tacataagag cccccaaaca taaaataaat
    11881 ttattgaaga ggagggcaac aaatgtctta caaaagtact tatcaagaag taattaaaaa
    11941 tttagactca agtttatctg gtttgagtaa agaaagagca gaagagttgt tagaaaaaaa
    12001 tggagctaat gaattaaaag aagcagataa ggttcctact tataagcttt tcctagaaag
    12061 ttttaaagac ccattagtaa taattctatt gatagctgct ttagtacaaa tatttttagg
    12121 tgaaacagtg gagtctataa taatttttgc agttattatt ataaactctg ttctgggtgt
    12181 tgtacaaaca aaaaaagcag aaagttcatt agaaagtttg aaaaatttat ctgcaccaaa
    12241 cgcaaaggta ataagagaca ataaaaaaat gacaattcca gcaaaaaatc tagtagttgg
    12301 agatattgta ttcttagaag ctggcgatta cataccagca gatggaaggc ttatagaagc
    12361 acaatctctc aaggttgtag aagggatgtt aactggagaa tcagaaccag ttttaaagca
    12421 tacagaaaaa ataagtgaag atgtaagttt aggtgaccag aaaaatatgg tatttagtgg
    12481 tgctgtagtt gtttatggta gaggttcttt tgtagtgact ggaacaggta tggatactga
    12541 aatgggtaaa atagctgggc ttttagaaag tgctgaaaat aaacttacac cattgcaaca
    12601 aaaaatagag gattttagta aaaaacttgg tgtaggtatt gtaatacttg ctcttttaat
    12661 atttataatt caagtagcaa gaaattactt tatggctgga aatggagaaa tgacacaaat
    12721 tattttagat tcattcatgt tctctgtagc agtagcagta gcagctatac cagaagctct
    12781 atcatcaata gtcactatag tattggctgt tggaacaaat agtatggcaa aaaaacaagc
    12841 cataataaga aaattaccag cagtagaaac tttaggttca acaagtgtaa tatgtactga
    12901 taaaacaggt actcttacac aaaataaaat gacagtagtt gattattata tgtatggaac
    12961 taataatgat gagttagata aagaaaaagt aaactattct tatcatgcta aattattgac
    13021 tatggtttct acattgtgta atgactctca tataactagt gatggtaaag aagttggtga
    13081 cccaacagaa gtagctttaa taaattattc aagtaaaaat gatttagatt atgataaatt
    13141 aagaagtaag tatatcagaa taaatgaaat accatttgac tcagacagaa agcttatgtc
    13201 tactgtaaat agtatatatg gagattatat aatgtttaca aaaggtgctc cagatattgt
    13261 gtttagtaga tgtaaatatg ctttgaaaaa tggttcaaaa gtagatataa cagatgagat
    13321 aatagaagaa tataaacata aaaatgaaga gttttcaaat agagcactta gagtattagc
    13381 ttttgcaata aaagatgtcc cagaagaaga ttttatacct tcaattgatg acgaacatga
    13441 catgacattg gttggaataa tggcaatgat agacccccca agagaagaag taatggatgc
    13501 agtaaaagag gcaaagagtg ctggtataaa aactgttatg ataactggtg accataaaac
    13561 aacagcagca gcgattgcaa aagagattgg tataatggaa gaaggagact tggctcttac
    13621 tggaaaagag cttgatgctt tgagtgaaga acaactatat gaaaaactag aaaatataag
    13681 tgtatatgcc agagtctcgc cagaaaataa aattcgtata gtaaaagcat ggcaacataa
    13741 gaataatata acagcaatga ctggtgatgg tgttaatgat gcacctgcat taaaacaagc
    13801 agatatagga atcggtatgg gaagtggtac tgatgtagca aaagatgctt ctgctatggt
    13861 attggttgat gataactttg caagtatagt aaatgctgtt gaagttggta gaacagtata
    13921 cagtaatata ataaaatcaa ttacttatct atttgcagga aacttaggag ctatagtatc
    13981 catagtattt gcagtgtttg caggttggtc aaatccattt acagctttac aacttttgtt
    14041 tataaactta gtaaatgact ctttaccagc aattgcatta gggtttgaaa agtcagaaaa
    14101 aaatataatg aataaacctc ctagacaccc ggatgaaagt atactagcag gaggaacatt
    14161 gaaggcagtt gctataagag gttgtataat aggtgtagtt acaataattg cacaatatat
    14221 aggattacaa gtatctccag aacttggagt agcaatggca ttttcaacat tgatattagc
    14281 tagaataatg caaacattac ctgcacgttc taataatcaa acagtaataa aattaggttt
    14341 tttcagcaat aaatacgtta taggagcagt tttagtctgt cttgggcttt actctttaac
    14401 actaatacca gtgctaagag gaatattctc tataccaaca acgtttggat tgtaccagtt
    14461 ggggatttgc ctagggttag cattaatttc atcaatatta atggaactta acaaattaat
    14521 aaatagaagt gaagtaaaat aatcaaaaaa ttaaagggca tattgatttt aacaatatgc
    14581 cttttataaa tagtctaatt tattctatat tatcgattat ttggaatgct tttataactt
    14641 caggtaattc tttttcttca ggcattctaa atcttataaa atttttatca agtccagtaa
    14701 aatcacttcc agatataact cttattttta atttagcaaa ctcttgttgt aaatctatgt
    14761 ccttgttttt atgttcaact gtcataattg atacagtatc actagtttca gctatattaa
    14821 ggtttttcca tggaattaat aattgatttt ttatatcttt tgttttttct tttaattctt
    14881 ctataaattg aacatcatct aataaatttg ctgcaatact acgagatatt tcagacactt
    14941 cgtaaggagt agaaatcttt ttaatagggc taacaagttg ttctggaaga actgcatatc
    15001 ctgctcttag tcctgctaaa ccaaatcctt ttgaaaatgt ttttaaagca attacattat
    15061 cataattatt tagaagcttg acagctgaat tttcttttgg catgtattca ccataagctt
    15121 catctaccat aactgctata tcatatttag ctgcttccct tactatattt tcaattgatg
    15181 ataaaggtat aatttgtcct gtaggattgt ttggattgtc tatgtaaatt actttatatt
    15241 ctggatttat tttttcaata aattcttttt cattaaactt gaaattatcc tctttcttta
    15301 aaagaacata atcataagtt gcaccatgca tttttatatc tgtctcatat tctgagaact
    15361 gaggtgaata tcctaaaact ttatctccct tttcaataaa tagtctattt aaaaggtaaa
    15421 taacatgtat agaaccatct gccaaacaaa ttctgtcagt atctaatgct ataaaatctt
    15481 tccaataatc gactatatta tcttttaaag caattgaatg aggatatcct cttatcatat
    15541 caaattttaa agcattaaaa gcttctacag ctttgtttga gtaagacacg gtatttatac
    15601 cttcaccaca gtctatctcg aatacatctt ctgaatgtcc agattctatt gcataacttt
    15661 ttttcaactg catttcaata gctttgttaa tttttagttt catactttat cactccttat
    15721 ttagtcaata ataaatgtta taaaagttgc tagatttaaa atattatgaa aatatataat
    15781 agtaaaaatg aatataaata ttataatagc tcactttatt taatatgatt atatatcata
    15841 tattgtaaaa tttctagcat tataagacta taaattgaaa atattcagaa aaatactaca
    15901 agaaacgatt tattttgctc ttaaaataag ttaaatgaat gttattaatt ttgtaaattg
    15961 aaatagttta agtataaagt tatgatataa tctaataagg gtaattcttt agattatatt
    16021 aaggaaatat aggtatacaa taaaaagtta tggagttgga ttatgggata taaattaatt
    16081 gtaacagata tggatggaac tttattaggc aataatcata aagttacaga tgaaaataaa
    16141 actgcactac aaaaagttat aaaaagcggt attaatgtaa ctttagcaac aggaagagcc
    16201 ttcgattcag ctaaatgcaa tgtagatttt cttaaagagg acatgccaat aatagcttgt
    16261 aatggttcat taataagaga gcaaaatgga aatataatat attcaaataa gattgataca
    16321 agaacatgtt taaacatttt agatgtatta gataaatacg atatttacta ccaatgtaat
    16381 agtatagatt ctatgctttc gaaaaaaata gaaggacgtg aagatagatt aagtgtattt
    16441 ttaggctctg aaacagaagt aattgtaaaa gatgatttga gagaagaaat ctttaaaaaa
    16501 gatatactaa aatttgtaat catagaagaa aaaaatccat ctattttgga tgaaataaga
    16561 aaagaattga gaaaagttca aggaataaag ataacctctt catggccaaa caatattgaa
    16621 gtcatgaatg aaggtgttga taaaggtaat gcagttaaaa ttttagctga aaaaatgaat
    16681 atagacagag aagatataat tgcatttgga gacaattaca atgacataga aatgataaag
    16741 tttgctggtc ttggggtagc tatgggaaat gcagaagaat tgattaaaca agaagctgat
    16801 tatgttacag atacaaatca agacagtgga gttgcaaagg caatttataa attcatagag
    16861 ttaaaagaat cacttagctc ttaaaacagt atataatagg aaaaaatagg ttgactattt
    16921 tgtagatagt aattataata caaatagata aaatataaaa atttagattc agtgaaaaag
    16981 agagtagata tagagaaaat ctcagcgaat tgggggatgg tgtgagccta atgataacac
    17041 tttatattga aaagaacttt ggagaatact acttgaaatt cagtatggta gtaggtaatc
    17101 tcgccttaag agaatagagt gggtaaacat tgtttaccaa ctagagtggt aacacggaat
    17161 atttcgtctc ttggtctttt tgaccaagag attttttagt ttcattgagt tacaagactt
    17221 ataattaaaa tacaaaaaat taaaatatga ggtgaaagtt atgaaattat ggggtggacg
    17281 ctttagaaaa gcggaaaatc aacttatgga agaatttaat aaatcttttg gctatgattg
    17341 tgtactgtac aaaaaagata tcgaaggaag tgtagcacat gttcatatgc aagtaaaatg
    17401 tggactttta acagaagaag aaggaaagtc tataacagaa ggtttaaaag ggatacttga
    17461 agatgtagaa aatggaaagt tagtattgga tggagagtat gaagatatac atagttttac
    17521 tgagataaat ttaattcaaa gaattggaga tgttggcaag aagcttcata cagcacgtag
    17581 tagaaatgac caagttgcag ttgatatgag attgtatgct aaagaaaaag caaatgattt
    17641 ggtggattta atatctgaat ttaaagctac tataaaagat gttgctgaca aaaacccagt
    17701 gatgatgcca ggctatactc atcttcaaag ggcacaagta gtgacattta agcatcactt
    17761 aatggcatat tatagtatgt ttgatagaga tgagaaaaga ataaaaaatg ctatagaaat
    17821 attagatgaa tcacctttag gctgtggagc tttagcagga actacgcatg atatagatag
    17881 aagtataact tgtgaacaat taggatttaa aaaagtagta gataatttta tggatggagt
    17941 aagtgataga gattatttac tagagctaat gagtgatttt tcaattataa tgatgcactt
    18001 aagtagatta agtgaagagt tgatactttg gagttctcaa gaatttggat ttgttgagat
    18061 agatgattta tatacaactg gaagtagtat aatgcctcag aagaaaaatc cagatggtgc
    18121 agagcttata agaggtaaga ctggtagagt atatggaaac ttatttggtc tttttacagt
    18181 aatgaaagga ataccattag catataataa agacatgcaa gaagataaag aaggtttttt
    18241 cgatagtgta catactcttg aaatgtgtat acaaataatg gatagaatga tagccacact
    18301 aaaggtaaat gaggataaaa tgaaacaagc agtaaaaaat ggttttttaa atgcaacaga
    18361 agttgcggat tatttggtta aaaataatgt tgcttttaga gatgcacatg gtatagtagg
    18421 aagtatcgtt atatattgtg aagataataa aaaagcaata gaagatttaa cattagaaga
    18481 attacaaaag ttttcagatg cttttaagga agatatttat gattttatcg actatgagag
    18541 tatattaaat aagggaataa aaaagaattt aaaataatgt atttattttt aaaagctgta
    18601 aatttgaatg ttatcattta aatttacagc tttttattgt gtaagatttt attatataaa
    18661 agtaagaaac ttaaaaggag tagtatttaa aataaataca aataaaaaat tattattaaa
    18721 atgataatta atatcaataa gtattgacaa aattatttct aaatactatt atatataata
    18781 taaataataa tgaaaatcaa tatcaaataa atgggaggaa atctaatgaa cttattagtg
    18841 attggtggtc atgaaagaat ggaaaaagat tatatggtta tggccaagaa aaaaggttat
    18901 aagacaaagg tatatactac catgtcatct aaattaaata attctatagg aagaccagat
    18961 gcagttgtca tacttacatc aactgtttca cataagatgt ctagaacggt tgagtctcaa
    19021 gctaaaaaac aagatatatt aatcgtaagg cataaaaata gtagtaaggt agcatttaat
    19081 gaatgcctag atatggttga tgaatgtctg ggaaattgtt caaaatgtaa gcttaaagac
    19141 aaacaaaaac aaaaaaatat ataggtataa aaaatacata aacataaaat taaaagtact
    19201 gagataatag ttataattat tatctcagta cttttagatt tataaggata agtatagtat
    19261 aaatttttta ttataatttc caactacttg ttactttttc atattttttt tacttctagc
    19321 tttttttctt tttttcttct ttatatttga agctattata aataaaacta aaagcactag
    19381 aatacctgca ataatcttaa caaaagtcat taaaacatta ttttcagtca aaaatggaag
    19441 actgctatca agattatttt ttgcaattaa gtctatactg ttttctagtt taccattatt
    19501 atatacattt aaagtaccaa ccttagctcc tttttttata ggcaaatcaa ttttatttaa
    19561 ctctgttttg gtatcataat ttccttgaga ttcatctttt tctaagaata tcctataact
    19621 attttttggt tcataaatca attcatgttg ttttgtaaac aatacttttt tagtatctgt
    19681 gtatttttct ttatcaacaa tagtagcaca cttaaaatta tcaaatccat aatcaatcag
    19741 aatacgtgag tctaaatata aatcagcatt agttgaatta aatacagcaa cgataactct
    19801 tctgccatct tttacagcac tcgataaaag acatttacca gcagcatcag tatatccagt
    19861 ttttatacca tcaactatat catattttat atttataggt tgacctttgt atgtaatctt
    19921 atcatgtgat gtcaaaaact tattagtgtt tacaaagtat ctctcataag gatatgcttt
    19981 tgtagcttca aatttaagtg acttagtttt tacaatttgt ctaaaagtat cattattcat
    20041 agcttctcta gctatgagag ccatatcatg agctgttgtg tagtgatttg ggtctggtaa
    20101 tccatgagga ttattaaaat gagtattagt agctccaatt ttttttgcct cagagttcat
    20161 gaggtcaata aatttttgta cattgccacc accaacatat ctagctaata caaaagcagc
    20221 atcattagca gaatgaacca aaagagcatc tagtaactgc tttacagtaa aagattcccc
    20281 attttttaga tacatactag agccatctat ttgaggtaaa tctttaattt ctattacttg
    20341 atttaaatct ttaacctcct ttagaactaa acaagctgtc catactttag ttgttgaagc
    20401 tggataaagc ttagaatttc catccttatt atatagtatt ttgccagact catagtccat
    20461 taaaactgca tgtttagcaa ctatagctgg ttcattatct gcaaaagaga tattagagct
    20521 tcctaaaaat gaagtaaata tcaataaaca gattaataaa agtgataaat ttcttttcat
    20581 tgtgagcctc caaattttaa attcatcttt tagtatagca tatatttgtc aataattaaa
    20641 agaaaggagt gattaatata tgaaaaaaaa agtaaaattt atttcgtttt ttgttttatt
    20701 tattttaata atatcatcaa taatcgttta taaatcgctt attttcaaag atgatattta
    20761 tgttgtaagt aaaaaaaatt tacctaatga aaaaacacat gttgtagaga atgaaattaa
    20821 aggtgaagat aataatcaca ataaagtaac taaagacata gataaaaatt ttcaaaataa
    20881 taaaataact atatacataa gtggagcagt aaatagacct ggaattgtaa ctatagagtc
    20941 agacaagaga ctttatgatg ctgtagaatt actaggagga acgacaaaag aagcagattt
    21001 aaatggagtc aatctatcag taagattaga agatgaacaa cattacataa tacccaaaat
    21061 aggtgaagca acatctgtta caagtaatga tgattccaat aaaccaaatc agaggaatga
    21121 gtcaagaggt gagcctaaaa ataaatccaa taaaaatata tctaacgaat caaaagtaaa
    21181 tataaatgta gcgactatag aagagttgga ttctctacct ggggttggag aagctacagc
    21241 caataaaatt ttacaacaca gagaagaaaa tggacagttt agttcaattg aggaaataaa
    21301 aaatgtaaat ggtattggag ataaaaagta tgaaaatata aaagatttaa tttgtgtaga
    21361 ctaaaatata atacaaaact tacatataga tatgttatta taaatatgta tgtatatgtg
    21421 tgtacatgtg gaaatttagt aaaggaggca cttttatgaa aaaagaacaa aaaaaactta
    21481 cagagatgac aacagcaggt ggttgagccg ctaaaatagg gccagaggtt ctggcatcag
    21541 ttttatctca attgcctaaa aatgataata tagaaaattt attagtagga ctagatacag
    21601 cagatgatgc tgcagtttat aaattaaatg atgatatggc acttatccaa actttagact
    21661 tctttacacc aatggtagat gacccatacg tatttggtca aattgctgca tcaaattcac
    21721 tatcagatgt atatgctatg ggaggcaaac ctttggttgc tatgaatatt gtttgttttc
    21781 catcatgcca tgatatggat gtacttgcag aaatattaaa aggtgggttt gataaagtga
    21841 aagaaagtgg agcacttttg gttggagggc atactgtaga tgacaaagag cctaaatatg
    21901 gtctttcagt ttctgggatt gtaagtccaa ataaagtttt atcaaatgct actgcaaaac
    21961 ctggtgataa gttaattata acaaaaccaa ttggagtggg tgtattaaat acagccatga
    22021 aagaaggtat ggtagaacaa catatagcag ataaagtaat agaaataatg atacatttaa
    22081 ataaatatgc agcaatgagt tttgagaaat ttgatgtaaa ttcggttaca gatataactg
    22141 gttttggtct acttggtcat actttagaaa tggccaaagc ttctgaagta agtattgaaa
    22201 ttgaatcaaa acatgtacca attattgaag gtgcaataga aatggcacaa atgggaatta
    22261 tacctgctgg tatgtataaa aatatgcatt atgtatctaa agatgtagaa gttgtaggaa
    22321 atatagaagt tgcagttcaa gatattttat acgacccaca aacatcagga gggttgttaa
    22381 tttcagtaaa agaagaactt gcagaggaac ttgtaaaaga tatgaaatta aatggagcaa
    22441 tagaagctaa aattataggt tctgtagttc caaaagggga aaaatatatt acagttttat
    22501 aaaatattat agagaaagag tgattgtttt gagcaaaaga gaattgtttg caatgttgcc
    22561 ttcagttgat gaagtattaa gtgataatag aattgtagaa ataataaatg aatatcctag
    22621 aagtttagtt ttagaatctg tgagagaagt aatagattta aaaagacaat ttatattaag
    22681 attaaaagaa gatgcatcaa actctgtaac aatagagttt ggtgaaataa tagaatctgc
    22741 aatagagaga gttaagttaa attactcatt atctttaaaa aaagttataa atgcaactgg
    22801 tacagttatt catacaaatt taggaaggtc tttacttagt gaagatataa aagatgaatt
    22861 atggtgtgct gcttcaaggt attcaaactt agaatacgac ttggataatg gagaaagagg
    22921 ttcaagatac tctcatttaa ctagtacaat aaaaagactt actggagcag aagatgtact
    22981 agttgtaaat aataatgcag cggcagtact tcttgtactt agcacaatgg ctaaaggagg
    23041 agaagcaatt gtatctcgtg gagaattagt tgaagtaggt ggttcattta ggattccaag
    23101 tataatggct cttagtggtg cagaattagt tgaagttggt tcaactaata aaactcattt
    23161 gaaagattac aaggaggcca ttacagaaga tacaaatgta ttgatgaagg ttcatacaag
    23221 taattataga ataatgggat tcacagagag tgtttctata gaagaattgg ttaatttagg
    23281 taaaaaatat aaactacctg taatagaaga cttaggaagt ggagttttta tagatttatc
    23341 aaaatatggt ttatcttatg aaccaactgt attggattct attcgacaag gtgcagatgt
    23401 agtaactttt agtggagata agatgcttgg aggtccacaa gcaggtatta tagttgggaa
    23461 aaaagagtat atagaaaaaa tgaagaaaaa tcaacttact agagcactta gagttgataa
    23521 gcttacaata tgtgctcttg aagcaacatt gagaatgtat ttagatgaga caaaagctat
    23581 agaaaatata cctactttaa aaatgttgac atataaaatt gaagaattag aagtaaaagc
    23641 aaataaacta tttgaaaaaa taactgcttt aaacttaaat gcaaacataa atatagaaga
    23701 tggattttca caggtgggag gagggtctat gcctcttgaa actataagta caaaggtaat
    23761 atcaataact cctgaacata tgaatgtttc atctttagaa aaaaaactaa gacttagtga
    23821 agcacatata atagccagag tgtatgataa taaatatgta ctagatgtaa gaactatatt
    23881 tgatgatgaa tttgatgtaa tagttgagga attgagaaaa gcatttaatt aaataaattt
    23941 gagttaataa atattaaatt tagaagtata agtatgaagt tttaattaaa aaatagctac
    24001 acacacttgt gactttagtc atagcaggtt tagagggggc aaaaaatgaa aaatgtagta
    24061 attggaacag caggtcatat tgaccacgga aaaactactc ttataaaagc attgactgga
    24121 agagagactg atacgttaga tgaagaaaaa aagagaggta tttcaataaa cttaggattt
    24181 acttattttg atttaccaaa caatagaaga gctggaattg ttgatgtccc aggacacgaa
    24241 aaatttataa aaaacatgtt agctggagca tcaggaattg atatagtttt acttgttgta
    24301 gcagcagatg aaggggttat gccacagaca gttgagcatt tagatattct aagcttttta
    24361 aatatcaaaa atggaatagt ggttctaact aagtctgata ctgtagatga tgaatttaga
    24421 gagctagtaa aagaagatat ttgtgaaaaa ataaaaggaa cttttcttga agatgctgaa
    24481 ataattgaag ttgattctat atctaaaaga ggtatagaca ctcttattga aaaaatagat
    24541 aaaatgagtg atgatataga agataaaaat gaaaactctc cagcaagact taatatagac
    24601 agagtatttt caataaaagg gtttggtact gtaataacag gcactttaat agaaggaaag
    24661 ataagtatag aagatgattt ggttatatat ccacaggtat taaaaacaaa aataagaagt
    24721 atacaagttc atggagaaaa taaagataca gcttatgcag gtcaaagaac agcaatcaat
    24781 atatcaaatg taaaagtgga tgatataaaa agaggagatg ttttagctgc accaaactca
    24841 ttagaggaat caatgatgtt agatgtaaaa ttatcattgg taaatcattt agataaagga
    24901 ttaaagcact gggatagatt aagattgtat catggaacta gagagatact ttgtagagca
    24961 gttccactag ataaggaatt aattgaaagt ggagaaagtg gctatgttca gtttagactt
    25021 gaagaaagca tagtatctaa gaaaggtgat acgtttgtag tgagatgtta ttctccaatg
    25081 gaaactatag gtggaggtgt aataattgac ccatctccta aaaaacataa gaaatttgat
    25141 gaaaaagtta tagaagcatt aaaaataaaa gaaaaaggcg aactaaaaga tataatagaa
    25201 gagtacttaa aaaggaattt aaaaaattat ccaaatataa aagaaataat gagctatagt
    25261 ggtgctcatg aagaagatgt aaaaagagcg cttgaaacac ttatatcaga agataaagta
    25321 tttattatag gaaatatgta tatgcatata aatcaataca ataaattaaa agaaaataca
    25381 ataaagcttt taagtgagta ccataagaag tataggctta gaaaagggat actaaaagaa
    25441 gaagtaaggt ctaagataga gagtaatttt aagactaggg agatggatat tttattagaa
    25501 aaattgtcta cagaaaatgc tataaaaata gaaaataata tagtatctct attagatttt
    25561 gaggttattt taaatgataa gcaaaaagaa atagcaaaaa aaatagaaaa aagattaaaa
    25621 tcatgtggag tttcttctat actgacaata gatgaagttt ctgaaggaaa tcataactat
    25681 gctgaagtat tggagtcaat gataggtaat aaagtagaga aattagatga cttgtatata
    25741 atggacaaag atatttatga aaatgcaaag aacattttga taaattatat aaaagaaaat
    25801 aaagaaataa cattaggaga atacagagat ttgattgatt ctagcagaaa gaattgcatg
    25861 attatattgg aaaacttcga tagaaacaaa ataactaaaa gagtagaaaa caaaagaatt
    25921 ttgttttagc agaaaatgtc tgtttttgct ttaaggtata aagaaggaat tataatgtcg
    25981 agtatcgtat aattaattag tataaaatat taattaagag gaagtgtaaa gtattgaaga
    26041 atataatacc tgatgtaaaa ccagatataa aagaaagaga agacatgagc cttttattta
    26101 taataatggg ctcagtactt ttattattta ttataaaaga tatagagaaa tatgaaactt
    26161 tattacatgc catatatacg atatttttag tagctacagg agtaattata tttaatacta
    26221 caaaatttaa agtagattca ttttctacat ttttaggatt aatttttata gctactggag
    26281 tattggagtg tatatattta tttaattcct tggggattaa aactaagtct ataatggaga
    26341 ttaacatcac aatatcagca ataacagatt tatttcctat actgggtgta tacttaagtt
    26401 ttaaatttgt taaggataac aaacaaattt attcaagtgt aattttattt atagcaactg
    26461 ctacattaac aataacatct ttattcataa tatcaggaat ttgtgactat ctgggaaatg
    26521 gtaaatcaca atatgcttta ggagttataa tatctatatt cataataatt atttctatca
    26581 ttagtggaat tgaattaaat tcaagttcaa ataaaggtaa atgggaatat gatgaaaaaa
    26641 agatttttaa cagaataata gtaataataa tcttatcaag agttccaaat ctattgcata
    26701 tagttattga taatagaaat gtagagagga tattatcaca aataataata aatgtagcct
    26761 tatattattt atataattac atagtatcta agaatattaa gaaaacagca ctggaattgc
    26821 atgatacgaa tgaagaatta acaaaaaaaa cggaaagttt aaaagaaaag aataaaaaat
    26881 taatctatga gacagaaaag atagaggaac ttaagggaat acttatgaaa agagaatcta
    26941 ggctacaatc tacattagat gtagcagtaa atagcatagt agtatttagc aaagatggag
    27001 aaattacata tgcaaataag agctttagaa atacttttgg agactataaa gaacaagata
    27061 aattgactga taaaataaaa aacttcaatg atttgataga aagcattcat tatgtgtttg
    27121 ttcatgagaa gaatgcagag aaacttatta gtacaagcga taataaagtt tatcaagcta
    27181 tatttgcacc tttaattatt gcttcacaaa cagaaggagt attgtgtgta ctagaagata
    27241 agactaagaa aaaggagtac gaacgcaaac ttattgaagc aaataagaga agtaaagatt
    27301 ttttagaaag tattggagat ggcatagtag tgcttgaagg taataacaaa atatatgtta
    27361 ataatgcatg tagggaaatt tttaaaaata atttagagag cattgatttt tcattagtat
    27421 gtaaaagtga agaaagtata gaaaaaagat atgtaataga tggtgaagta aagtatgtag
    27481 agatgagttt ttctcagtat actaatgctg gtactaataa aactattatt gtaatacgtg
    27541 atacaacctc tcgaaaaata tctcaaataa aacttgagga aagtcaatca tcatattcaa
    27601 gatttataga tatattacct gatggcatat gcttattaaa agaagattta agtataaact
    27661 atgcaaataa gtcgttttta gatatgctag cttttacaaa catagatgat ataaaagatt
    27721 ctaatattaa actattaatg aatgcgaata ctgaagaaaa aatgaaattt acggataata
    27781 tggctaaagt tttaaatgaa aatagaagta tacttttact ggaatatgaa ttgataaata
    27841 gttatgatga tatagtagaa gtagaattaa gtgcattacc ttttgctata tacaatacta
    27901 gatacataat gcttattata aaagatttag tacataagaa atattccgag caagcagaaa
    27961 aagaactgct tgaaagattt aaaacagata aaatcaaaac ggagtttttt gcaaatatgt
    28021 ctcatgaact aaaaactcca ctaaatgtta tatctagttc aaatcaactg gtagattctt
    28081 tctatagaaa tgaaaagata aaagattaca ataacaatat taaatctcat gtggatttag
    28141 ttagacaaag ttcttatagg cttcaaagat taataaataa cattatagat ttaacaaaga
    28201 tggagtctgg gttctataca ctaaaacttg cgaaatacaa tattgtatct gtaatagaag
    28261 acttatttat gaatatagaa gagtatgcac ttagaaaaga cataaaaatt ctttttgata
    28321 cagaccttga agaaattaat gtttatatag acaaggttga aattgagaga attatgttga
    28381 atctattgtc aaactgtatt aagtttactg ataatggagg atggatatat gtaagtattc
    28441 attataaaat agataaagta atcataagtg taaaagacac tggagttgga ataccacaag
    28501 ataaattaga attgattttt gaagaatttt cacaagttga taagacttta tccagaaata
    28561 ctgaaggaag tggaataggg cttgctatag ttaagaatct agtaagtctt catggtggag
    28621 atatagaagt agtaagtgaa gtgaataaag gcacagagtt cttaatttca cttccaatga
    28681 agggatttag tagtgaacat tatacagaag ataagagaat atataatatt caagaaaaaa
    28741 taaaaataga attttctgat atatactatt aaaaatgatt atgagcaaaa ataaaataaa
    28801 agtactattt gtttaaatat ttaagttgta agaaataggc tatcataagg taaattatta
    28861 tgatagccta tttttagcta ggttttatat ctatatgtga gaacatataa tctctaaatt
    28921 accttcaaaa ctaaaatctc caaagtcgtt tggtagtata aaatgcatac ccttttttaa
    28981 attgtattct acagaattgt gtataagttt tccatttcca tccaacacac tgtataaaga
    29041 aaaaggtgta ttgtgtgtaa aattacattt tccaaaaaca tctaatttat aaacactaaa
    29101 aaattcgttt gacacaaatg ttgtgcattt aaaatctgat gttgatacga ttttatagtc
    29161 agtatcgaaa tttatatgag gaacattcgt aacatctatt gatttttgaa catgaagttc
    29221 acgcttatta cctgaattgt cagttctatc ataatcatag actctataag tagtatctga
    29281 gttttgttga gtttctaaaa tcaatgttcc tttgcatata gcatgtatag taccacttgg
    29341 aacatagaaa aagtctccct tttttatatt aacctttcta agtagtttgt cccattcatt
    29401 attatttacc atatttacaa attctttatg agattttgca ttatgaccta ttataatttc
    29461 tgcatcatca gaacaatcta ttacatacca acactctgtc ttacctaact ctccattttc
    29521 atttttttta gcatattcat catttggatg aacttgaact gataaattat catttgcatc
    29581 caatattttt gtaagtaaag gaaacttatc accaggtgtg tttccaaata attctctatt
    29641 tttattccac aattcagata gttttttacc tttatatttt ccattttcta ttaagcaatc
    29701 tccattttta tgagagctta tagcccaaca ttcaccagtt gttggcgaat ctatttcata
    29761 attaaattta tctttaagtg cagtaccacc ccatattcta tccataaaaa taggttttaa
    29821 aaataatggt tccataatcc tgttcctcct atgatattaa atttatccta caaataatta
    29881 tatataaata gattataaaa tcaatagtaa aaaagttttg tcccttgaaa tgacataaag
    29941 tataaggagt tattaaataa gataaactat gatatataat ataaagttct aaattggagt
    30001 gataattatg gagttgttta aggcagaaag caaaaaatat gaaaaagaat ttttaaaatt
    30061 attggagcaa tgggttagta taccttcatt ttatgataga aaaactgtat ctaaagatat
    30121 gccttttgga aaaggagtat atgatgcatt aaactggttt gaaaatctag gtagagaaaa
    30181 caatttcaaa gtaaaaaata tagataatca tgctgttcaa attgaatatg gaaatggtaa
    30241 agagtatgta gatatatttg gacattgtga tgttgtaaat ccaggtgaag gatgggatag
    30301 tgaaccattt aaactaaata ttataggtga taaattagtt gctagaggtg tatctgataa
    30361 taaaggccct atgatagtga attttttagc actaaaaatg ataaaggatt tagatattaa
    30421 tttaaaaaga aaggttagat taatagctgg gggaaatgaa gagagtggat ttaaatgtat
    30481 aaagcattat tatagcaaag agccatatgg tgtatgtggg tttactccag atgctaaatt
    30541 tcctgtatta aatggagaaa aaggtggagc aataataaag ttaatttcaa atatagacga
    30601 taaatcttta tatataagtg gtggaataga gtttaataca ataccagata aagtttatat
    30661 aaagaatgta gaaaaattgg gtaaagataa tatatgtttt gatattaaca atatatcgat
    30721 aaattatgat aatggcaatt atattgtgta tggaaaaggt ggtcattcat ctaaacccga
    30781 aaaatcaata aatcctatat tagctacaat taaacttttg tcagaaaata ttgatgaaaa
    30841 atggacaaaa gatttatata agttgataaa tcaagataat ataaatggaa acttatttgg
    30901 tttaaatatt gaggggaaat gtgggatttt atcaatggtg ccaacaataa taaatatagt
    30961 agatggaaaa ttagaagtag ttttaagcgt tagatatcca gaaatattaa ccattgaaga
    31021 tataataaaa aaatttaatt tgtatatgga gcaaaataat attaataaat ttgagcttat
    31081 tggggaaaat ttaaagcaag caaattatat agatagaaat tcaaaacttg taagaagttt
    31141 gcatgatata tatataaagt attctggaga tttaaaaaat gatgttagag taactagtgc
    31201 aggaagttat gcttctgaaa tgaataattc agtaatattt ggttgtgaat ttcctgatgg
    31261 tagctttggc aatgtccata gtgcgaatga atttgctagc ttagatagat ttataactgc
    31321 aataggtata tatgcagagg caataattac attatgtaat aaaatataaa tacaaaatgt
    31381 cccttatata gacatattat atatacaatt aaaattttac ttgatatata attgaaatca
    31441 aagagaaggt gatacaatga taactaagaa acatgcaata atagtaaaga gtttaagcaa
    31501 taaagatgga tatatgacat caaacgaatt agctatcaaa ttggatgtgt ctactaaaac
    31561 tattaaaaga tatatagcag atttaaatag tgttttaagc aagtatgatt tggtaatagc
    31621 ttcttctaga ggtataggat acaagttaag cggttctaaa aacaatatag ccagagctat
    31681 taaagaagca aataaatata ttgatggttt tttagatgac tctgaagagt caagaatgtc
    31741 aaatataata tgtatgctta ttaatagaaa ttatatgagt atagaagcaa tggcagaaga
    31801 attaaatcta agtatagccg ctataaataa attgtctagt aagcttaaaa gaaaacttga
    31861 aaagtatgac ttagttataa aatctaaacc ttactatgga agctatatac atggtgaaga
    31921 aattaatata aggcaattaa ttactgacta tgcaataaaa ttagatgaaa aaagtaaagt
    31981 gaaggtgttt ttagatgaca ttagtgaaaa cgatatacac tttatagaaa gtattttaga
    32041 aaagcactta agagaaaaag atacaataat ttcagataaa gattttaatc ttttgctttc
    32101 aaaaataatc gtttctgtat ttaggagtaa gagaggtcat agtaacaata taaacttaat
    32161 ggatacaagt tatagatttc ataactacta ctttatagaa aatctaatga aagaaatatc
    32221 tgataaaatt ggatttaaac ttattgaaga tgaagtaatt tatatttcaa attattctgg
    32281 tgtaatagcc tataaaggta cacaaggaag aaaaaacaca agtgaaattg aggaacgaat
    32341 aagtagtgtt ataagtagtg cacttcaaga tatattcctt atttcaggta gtgattatac
    32401 aaaagatgat gagtttatgg ttgcaatctc tgaccatata aagagatttt taaatagagc
    32461 tagagctaat gtaaaatcaa ataatccttt acttcatcaa ataaaagaga agtttcctat
    32521 agcttttaat ttagccgtgt ttttatcaaa taaactagaa actgagttta atttaaaact
    32581 tgatgaagat gagcttggat atatagctat ccactttgct gcttcaaatg aaagaatgaa
    32641 aaaaaatact agtaagaaaa tttgtatagt ttgtcattat gggataggaa caggacaact
    32701 tatttctgaa aagctaaaac agaatataag tgatttaagt gttgtgggtg tttatccagt
    32761 tagatatctc gatatggcta taagtcaaga tgttgatttg atagtatcta ccgttgaatt
    32821 aaaaggatat gaaaaacctg tcttatatat agaaaatata tttgatgata gcttaattga
    32881 aaacgtaaac aaagcctttt atgaaaagga agaaagaaga aagataataa gcaacatgtt
    32941 tgatgaaaaa gcttttttca gtataaaggc taatactaaa gaagaggtca taatttcact
    33001 ttcaaataaa ctaaaagaaa gagattttat agaggaaagt tctataaaaa gtataataga
    33061 tagagaaaat atttcatcaa ctgaaatagg aaatctagta gcaatacccc acacaatagt
    33121 gaagggagat aaaaaatcta taataggagt tggaatactt gaaaatccaa taatttggga
    33181 taagcaagag gttcagctag tatttatggt attttttaat actaaagaaa aacataattt
    33241 ctcgatattt aaataccttt ataattttat aaaagatgaa ggcggagtaa gaggaattat
    33301 taaaatatgt gactttaata aattaatggc actgataggt aattaaggag gaaattaata
    33361 atgggaacaa acatatttaa caaagaatat gtatttttaa atgttgatgc taagtcaaag
    33421 gttgaagttt taaaatttat atcaaaaaaa gctaaagact taaacttggc agaagatgag
    33481 agcgtagtat atgaaggttt aatggctaga gaagaacaat ttactacaaa tttaggagaa
    33541 tctatagcaa tacctcacac taaaaatgat gcaattgaaa atccagcagt agtagtattg
    33601 aagtttaatg aagatgttgt ttggaatgaa ggtgaggata aggttaaatt agcaataagc
    33661 ttacttatgc caggaaaaag taaagagaat attcatctta aattattatc atctctttca
    33721 agaaaattaa taaataaaga atttaaagat tctcttttaa aaagtgataa tgttgaagaa
    33781 atatctaact taataaatga agctttaggt ttataattaa acactaaggt tataaaataa
    33841 aaaaataatt aactaaaaat aggaggaatt tgaaatgaat aaaaaattag tagcattatg
    33901 tgcttgtcca atgggactag ctcacacttt catggcagca gaagcaatag agcaagcagc
    33961 aaaggcatta ggttatgaag caaaagttga aactcaaggt gctgatggtg tacaaaatga
    34021 gttaacaaga gatgatatat taggagcaac tatgataata catgcagtag caataacacc
    34081 agaaggtatg gaaagatttg atggttgtga agtttatgaa gttgaattac aagaagctat
    34141 aaaaaatgca gaaggtgtta taaaagaaat agaagaagat ttaggaatat aataaattta
    34201 ttgtggagga aatagaatgg caattaagaa aaaagttata aacagttcag gtgcttctac
    34261 aacaggagga aataatgtag gaaaatctac tccatctagt ccaactcaat caaagggaaa
    34321 tggaaaatgg aaagaaataa gtaaacatat aatgacaggt atatcatata tgataccagt
    34381 tttagtaatg ggtggactta taggggcctt atctcaatta ataccatatg ctatattagg
    34441 acttgaccca tctgtaggta tagttgatgc tatgaactca ggagaattta cagggttcaa
    34501 gcttagtctt ttaaatatag cacaattaat gtcaaatttc ggatttactt tgtttggatt
    34561 tgcgatacca ctgtttgcag cattttgtgc aaactctata ggtggaaaaa cagctttaat
    34621 tgcaggattt ataggtggat atatagctaa taaacctgta ggtgtaccac aattcgttga
    34681 tggacaatgg actgaagttg ttccagttgc atcaggattt ttaggtgcaa tactaatagc
    34741 attcataata ggatattttg taaaatggtt aaataaatct ataaaagttt ctcataactg
    34801 gttagctttt aaaacaacat ttttaatacc attaatagcg tcattagctt gtatggtatt
    34861 gatgatattt ataataactc catttggtgg attaattaat gaaagtatga aaaacttctt
    34921 aacagcagca ggagcagctg gagaatatgt atatgcaaca gctttggcag cagctacagc
    34981 attcgactta ggaggaccaa taaataaagc agcaggattc gttgcacttg gtttaactac
    35041 agagaatgta cttccaataa cagcaagaac aatagctata gttgttcctc caattggatt
    35101 aggattaaca acattattag ataaaagatt agtaggaaga agagtatatg atagacaatt
    35161 ctatcaagca ggaaaaactt ctatattctt atcatttatg ggtatatctg aaggagcaat
    35221 accatttgca cttgagagac caggttttgt tataccttta aacatagttg gaagtgtaat
    35281 aggagctatt acaggtataa ttctaggagc aattcaatgg ttcccagagt cagctatatg
    35341 ggcatggcct ctagtagata acttatttgg atatataata ggtatagcag ttggtgctat
    35401 attcatagca gtaggaaata tattctatag aaataaatta ataaaagatg gtaaacttgt
    35461 tgtagattat atcgactagt atttaatttt tactatctat aaataacttt ggctggtaat
    35521 atggttttaa tcaatattac cagccttacc tatatgatta attaaaggcg gtggagataa
    35581 gatatggata agatagaaaa agtaagagag tattttagag aatatgatat agatggattt
    35641 cttataaata gtcctacaaa caagttttat gttggaaatt tatttagctc ttcaggttat
    35701 gtttttataa ctaaagaatc acaatatata atagtagatt ttagatattt tgaagaaatt
    35761 aaaagaaaat ctagtttgtt taatgtagta ttaatggaca aaactagaac tcattttgat
    35821 ataattaatg atatttgtag agagcagaat ataaaggaaa ttggatttga gggaaatgaa
    35881 gtatcttttg atttatatag aagtatgagt aataagttaa gtgcaacctt aaaatcagtt
    35941 gatttatcta cattaaggga aacaaaaaat gaagacgaaa taaaatatat aaaaaaagct
    36001 tgtgaaatag ttgatgctac attttatcat atagtagact ttataaaggt tggtatgact
    36061 gaaaagcaag ttgaaaatga aattgttaga attataaaag atttaggtgg tcaaaaagaa
    36121 tctttcgata caatagttgc atctgggctt agaggagcat tacctcatgg aaaagcaagt
    36181 gaaaaagtta tagagtatgg agattttgtt acttttgact ttggtgctaa gtataataat
    36241 tattgttcag atattaccag aaccatttgt atgggtacta taaataaaga gttagaagaa
    36301 atatataata tagtaagaaa agctaatgaa gagtgtataa gggttttaag accgggaatg
    36361 actactggag agatagataa agttgcaaga gacataattg gttcatatgg atatgctggt
    36421 aattttggtc ataatctggg tcatggtgta ggaattatgg ttcatgaata tcctgcatta
    36481 gctcctgaat caaatgaagt attaaaagaa ggaatgattg taactataga gcctggtata
    36541 tatgttccaa gtcttggagg cgtaagaata gaagatgatg tacttataac aaaagatgga
    36601 tgtatgagat tgactacatc tactaaggat ttaatagttg taagctaaaa ataaattaga
    36661 taaatatttc ataacaataa gaaaagaaga ggtaaattta aatgtataat tttgatgata
    36721 aaccagatag agtaagtgaa aagtgtagaa aatgggattt aaatattata agagataaat
    36781 ttggagatat tagagaagat tttgtaccaa tgtggattgc tgatatggat tttaaaatac
    36841 caacagaaat agaaaacaaa tttattgaag ctgtaagaag aggtgtattt ggatatacat
    36901 actgttatga tgaattttat gattcagtta ttgggtggca aaaaaatatg catgaggtaa
    36961 atgtagaaaa agaatggatt acattaactt atggaactgt atcaacactt cattatgtag
    37021 tacaagcttt ttgtaagaaa ggtgatagta taatattaaa tacaccagtt tatgaccctt
    37081 ttgaatcatc agcaaaaaaa caaggtgtaa atgtagtttg taatacacta gatgttgtaa
    37141 atgatagata ttatataaat tttgataaat tggaaattca aattaaggaa aataaaccta
    37201 aattaatgat gttttgtaca ccacataatc cttctggaag gatatggaca attgaggaaa
    37261 tgacaagagt agcaactata tgtaaagaaa ataatgttat tttggttgca gatgaagtac
    37321 atgcagagca tattcattat ggtaaattta attcaatact taagattgaa aaagagcttt
    37381 tagaaaatgt tattctattg acatcaccaa ataaaggatt taatcttggt ggattaaaga
    37441 cttcttattc aatagttata aataaggata taagagatat atttagaaat aaactaaagc
    37501 aaaattctat aacttctcca aatgtgtttg gaataatagg attgataact gcttataatg
    37561 aatgtcgtga gtggttaagt ggtgtaaatg aatatataaa atcaaattat gaacttttag
    37621 aaacttgggt aaataaatat aataagataa aattgatgaa gatggaatca tcttacttag
    37681 cttggatgga tataagtgga ttaggtatta gtgcaagtga gtttacagat aaattggcta
    37741 tagatacagg agtattatta gaagatggga gtcattttgt aaaagatggt gagaagtatg
    37801 ttagaataaa tttaggaact caaaaggaaa atgtaattga agctttaaat agaatggatt
    37861 tatttttaaa gtctttataa aaatttggtt gaattagtat tttatataaa tttaaactat
    37921 taatatggta tatacataag tagaatttgt tttagattac ttaagtatat accatatttt
    37981 atataaaaat taaatttgca ttagtcatgt gataactatt taaattcata tgtattttgt
    38041 atgtataata gatataatta ttatttaaac ttattgttta tttaattttt caatagaaaa
    38101 agatttatct gtaagtttaa aattatcttt tataccctta gttaagtata ctttcttatc
    38161 cttagttatg aatatagcat ctacattatc aattttatta attaaattca tacctttttc
    38221 aagaccaagt ccaaatgtag aagtggataa ggcatcacaa ttaatagatt tatcagagat
    38281 tattgtaaca ctacttaaat tgttttcaaa aggatgccct gtaaatggat ttaacatatg
    38341 atgatatatt tttccgtctt tttcgataaa tctttcataa attccagaag taacaacaga
    38401 tttatttgta gtttctatgt ttcctatgga ttcaccattt ttactagtgg ggtcttgaat
    38461 acctatttta aaaggtttat catttttacc attttctaaa gtaaatatat ttcctcctaa
    38521 gtttactaaa ccttttttta cgtcctctga ttttaaatag gctacaattt tatcagcagc
    38581 atatccttta gctatggcac ctaaatcaat tttcatattt tctttggtta attttataga
    38641 tttatttttt tcatccaata tgatgttctt ataatcaata agaggcagaa gtttttgtat
    38701 ctcagaatca cttggaactt tagctttatc tgttccaata gcccataaat ttgataatgg
    38761 accaattgtt atgtcaaaat atccatctga taatttggaa tattgtatag cttcttttac
    38821 gacgaaaaat gtatcatcag aaactctgac aaatttttta ccagcattat catttatttt
    38881 agaaacatca cttcctggta tatgagtgct cattttgttg tcaatatatc ttaaaattga
    38941 atcacattca tttaagattt tatcactttt ggattctttt acattaaata cagtaacttc
    39001 gtttactgta ccaaggtagt agctagtttt actatattta gtattctggc ttgaactcct
    39061 aaaaaatgaa aataaaatta atgctaaaat caatatcaca aaaataaatg tgattttttt
    39121 cttattcatg gtatattcct cctatgaaat tgtgttatta ttttattata acataatttc
    39181 ataggaggac aaaaaatgaa gaaaaaagac attcttctta ttttaggcat tttggttgtt
    39241 attacagcat gttatgggat aataaatgtt ataaattcta aaaatgctgg aaatattgag
    39301 atttatgtag ataataaatt gtataaaact gtttcaataa atgccaaaga agaatttaaa
    39361 atagagaata gaggggggta taacatagta aagattcatg ataaaggggt tgagatagta
    39421 gatgcttcat gccctgataa ggtttgcgta catactggat ttataaacaa gccaagtcaa
    39481 agcatagttt gtatacctaa tagagtgagc ataaaaataa atacaaatga aaagaatgat
    39541 aatcaagaag atataatttc taaataaaat aataaaaata attgaaagga attggtgata
    39601 attatggtta acttaggaaa cgattgggat gaattattga aagaagaatt tgaaaaagat
    39661 tactacttaa acttaagaaa atttcttata gaagaatata aaacacgcca aattttccca
    39721 aatatgcaca atatatatga agctttaaaa cacacttcat acaaagacac aaaagtctta
    39781 atattaggac aagaccctta tcatggagat aatcaagctc atggtttagc tttttcagtt
    39841 caaccacaag tgaaaactcc accatcttta ttaaatatgt ataaagaatt aaaagatgat
    39901 ttaggttgtt ttatacctaa taatggatat ttaatgcctt gggcagacca aggagtgtta
    39961 cttttaaata ctgctcttac tgttagagcg catgaagcta attctcataa gaacaaagga
    40021 tgggaaattt tcactgatag agtaatatct attttaagtg agcgtgaaga cccagttatt
    40081 tttgtactat ggggaagtaa tgcacgtaaa aaagtagagt tgattgatac aagtaaacat
    40141 tatattttgg aagcacctca tccaagccca ttgtcagcaa gtaaaggctt ttttggatgt
    40201 aaacacttct ctaagataaa tgaaattttg aaaaagctag gaaaagaacc tattaattgg
    40261 cagatagaaa atatataaaa gtaaaaggta acaaaatgat aacaaaacaa caataaacaa
    40321 tgacattgtt gtaactaata gaaatatgct taaatagttg aaaatactat gtatgcatat
    40381 ttctattttt ttgtcaagtt gacaactctt gaaaaaatag ttacaattta gttacacaaa
    40441 aaacacaaat aaaaaaagaa acttacaaag cagaatttta tgaagcaaaa tatatagtgt
    40501 aaaaaatctt agggaggaaa ttttatatga attttaaaaa attgagtaat gctaaagtct
    40561 cggtaatggc agttgtttta tcagttggaa tattatcggg atactctgcg cttaataaac
    40621 aagtaacatt agtagtaagg ggagaagaaa gaactatatc aacatttagt tctaatgtag
    40681 gagacctttt agaatctcaa aacattagct atgattcaaa tgatatagta actttagatg
    40741 aaaatacaaa gttatctaat ggagataaaa tagaagtaat tgatgtaaag gaaaaaacag
    40801 ttgtagaaac taaagacatt ccatttgaag ttacagttgt tgaagatggc tctttattaa
    40861 agggtgattc taaggttaaa gaagaaggaa agtctggtaa aagtgaatta atatataaag
    40921 aaacttatca caatggaaag aaagtagaaa aggaatttgt gaaaaaggtt gttaaagctg
    40981 agccagtaaa taaggttgta agcaaaggga caaaggtaga aatgcaagta gcctcatcaa
    41041 ggggagaaag ttcaagaaga atggcttcat catcatctag tagcagtagt agtaacaatg
    41101 gtaaaaatat gagagtggta gcaactgcat atactggtca cagtataact gcaacaggaa
    41161 caaaacctaa gtggggaaca atagctgtag accctaaggt tataccatat ggaactaaag
    41221 tttatatacc tcaatttgac atggtgttta ctgcagaaga ctgtggtgga gcaataaaag
    41281 gaaataaaat tgatatctac atgaatgatt caaaaacagt ttataactgg ggaagaaaaa
    41341 ctatagatat acgtatatta aaatagttaa ataatttata tttttactgg aaattatatt
    41401 ttgattatat agagaagaaa ctctttatag attctaaaaa tataatttcc agttttttat
    41461 tttggatatg taataaaaca ggtaaatttt aaccatgtat agataaaagc tatttaaatt
    41521 ataatttact atcatataaa tctataaaaa ttgttgcaaa gagtcaaaat atatgatatt
    41581 atagatttcg ttgagaagga tttcattatg ggagtggatg ggtgccggtg tgccctctag
    41641 tcttcaaaac tagtatgagg ggttaagagc ctcttaggtg ggttcgattc ccacgcattc
    41701 ccgccaatat gtaaaaggta tcttttaatt aaaagatacc tttttaaatt tattttaaga
    41761 taatttattt ttaataatat ataatgtttt gtattatata atgtaaattt tctaatacta
    41821 ttatatattt agataaaaat ctaggagtgt ggaaagatgg aaaataattt tacaacgaga
    41881 actagttttc tagttggaga tgatgggata aaaaaactta ataattcaaa tataatagta
    41941 tttggagttg gaggagttgg tagttttact gttgaagctt tagcaagagc tggagtaggc
    42001 aatattacta ttgtagattt tgatgatgta gatataacca atataaatag acaaatacca
    42061 gccctacatt caactgtagg aagatacaaa gttgatgtca tggaagaaag aatattagat
    42121 ataaatccta atatcaatat aaaaaaaata agaagtcttt ataataaaga tactagtgac
    42181 gaaatactaa ctgaaagata tgattatgtt gtggatgcga tagacatggt aagttccaaa
    42241 atacatctaa ttgaaacttg tgaaaaaaaa ggattgaaaa taataagttc tatgggtatg
    42301 ggaaataaat tagacccaac taaaatagtc gttacagata tacacaaaac aagtacttgt
    42361 cctctagcta aagttatgag gaaagaactt agggatagag gtatcaaaaa gttaaaagta
    42421 gtatattcta ctgaacaacc aatagaactt aagaagaaag taatgaatgg tagaaaagta
    42481 acacctggta gtgtatcatt tgtcccatct gtaggaggtt taataatcgc atctgtaata
    42541 gtaaatgaac tattaggaca ataagtttta aatattttaa tttataaatt ttatatacaa
    42601 atttgaaggc tagaagcatg aatacaaagc aattttatat tcatactttt agcctaatta
    42661 ttttatatta ccttatttta tgtagttgta gttttatttt ttagattatg tatctatttc
    42721 ataattatat tttgtaaata taatttctcc atcactataa aaaacaatat ctcctattct
    42781 gtctgttcta taaattgata catggttttg ttttagatta ttaataacct ccctatgtgg
    42841 atgaccatat tgatttttat atccacatga tattgcagct atatctggac taattttttt
    42901 tataaattct aaagatgaag aagaattact tccatgatga cctattttta taaaattaat
    42961 attatttaat ttaaaagaat gtaaaatttc tttttcattt tcttcttcag catcacccat
    43021 aaataaaaaa gaattatcat taaaagttaa tttgaaaact atagaattta aattagattc
    43081 ttcttgtata tatgatggac ttaatacata tatatttata ttgttatcta tgtttaaaac
    43141 atcattttta tagagatgct gaatagataa gtttttatcc gtacaagaat ttattagatt
    43201 ttgataagcc tcactatcag ttgattgttc aggcatatat atggagttta cattaaattt
    43261 ttttataata ttatcaagac ttcctatgtg gtctgaatct ggatgagttg ctattataat
    43321 atcaatagtt tttattcttt tttgtctaag ataactaata attatatttt cgctatcttc
    43381 atcacctcca tcaattaata tattcttatt tgtgggtgtt tgaactaaaa tactatcacc
    43441 ttgtccaaca tcaatcatat gtatagatag tagagatttt ttgtcacagc cgattaaaag
    43501 tgatattata ataagtattg ataaaaaaat tttatttctc aataaaaaat cactccattc
    43561 attacatgtt tatataaatt tatgatgggt aatataagat atatatgact tattatattt
    43621 tatattttaa acaatataaa tgaaattaat accataataa aattggagtt ttttatatat
    43681 acaaaataaa atttttaaaa ttaagcaata aaaaaggtag gaggatttta tgtttttcaa
    43741 agatattgaa ctaaattcaa aaaaagagtt agacccatat tttgatttag tagattatga
    43801 agcttgtgag tactgtttta gtactttata tatgtggcaa catgtttata agacaggata
    43861 ttatataggt gaagattttg ccgttttagt tggggaatac gaaggagata gcttctcaat
    43921 attaccactt gctaaaaaag ataaacttcc agaagttgta gattttgtcc ttgaatattt
    43981 ttctaaaaat aataaaaaaa tatacttaag aggtattact actgaagtag tagagttttt
    44041 aaaagaaaaa tatccaggta gatttgagta tatagaagaa agagatttat ttgactatat
    44101 ttatgatgca gaaagtttaa gaactctagc tggtaaaaag aatcaaaaga agagaaacca
    44161 tataaactat ttcttaaaag agtatgcagg tagatatgaa gctaaattat tagataaaga
    44221 aaactttgat gagtgtttag tactaatgaa ggaatgggaa agtaataagg aagaaaataa
    44281 tgaatttgat gaaagtatgg atgatgaatt aataggtatc aaaaagatat ttaaccatta
    44341 tgacatatta aaagataagg taaaagtgtt tggtgtttat gtagatggaa aattagaagc
    44401 ttttagtata ggagagcttt taaatccaaa tatggcattg attcatatag aaaaagctaa
    44461 tcccgatata agaggtctgt atccatttat aaatcaacaa tttttggtaa gtgaatttaa
    44521 ggacgttgag tttgtaaata gagaagaaga tttaggtatt gaaggattaa gaaaagctaa
    44581 actttcttat catccttgca gatttgttga aaagtacagt gttagggagg cttaatagac
    44641 tatatggaga ttaggtatgc taaagaagaa gagatagaaa gtataaaaga gatttggagt
    44701 tattgtttta acgatacgga gagttttatg aagtactatt ttaatgataa atataaatct
    44761 gaaaatactg tagtagcttt agatgaagga aaaattattt cttctcttca gctaaatcag
    44821 tataagttat tactaaatag caaggtatat aatacatcat atgtagtagg agtttctaca
    44881 cttccagagg gaagaggagc tggatatatg aacaaagtaa tgaaatttac tttaaacgaa
    44941 ttgtataaaa aagggcaatt agtttctata ttgatgccta ttgactatag actttataga
    45001 agatttggat atgagcattg ttacgaccag attgaatata ctattaacac agatgattta
    45061 aaaaatttta agtcaagtgg aaaaatgata aagtctaatt tatcacaaat tgatgatttg
    45121 atacaaatag atagaacttt tttaaatgag gttaatggta atgtgttaaa agatgaacat
    45181 tattatgaaa acttatttaa agagattcaa agtgaagatg gatttttata cattcatgaa
    45241 ggaaatgaaa aagatggata tatagtttat tttcttcagg aagataaaat gtttgtcaga
    45301 gagttatttt ataaaaatat agatgccctt aaatcaatgc ttaaatttat atataatcac
    45361 aatactcaat gtaagatagt tactatatct actcctacaa tagataagat aaggtttata
    45421 ttagacaacc ctaaagatag tgatataaaa ataaaacctt ttatgatggg aagagttata
    45481 aatgtaaaga agtttattga agatatagat attgagaatg atattaatag ctcatttaat
    45541 ttattaatag aagacaagtt tatagatgaa aataatggtc tatttaaaat ttctatacag
    45601 aataagaagg tatctgtaga gcagttagat aaaaaaggtg cagaaaagcc tcaagaagat
    45661 tttgatatta aattagatat aaatacctta acacagttat cattttctta tatagatgta
    45721 aatgaagcta ttttcttaaa tgatataaaa gatgtttcag aagaaacact agaaacactt
    45781 aattgtattt tttctaaaaa aaataactat ataaatgaat atatataggt agagtacgtt
    45841 aaaagatttt aaaaatcttt tgacgtattt ttttgtttag ataacaattt atcttgttta
    45901 aaaattttct atttgaaaat aatctaaata atatactttt atatgggagt gattataatt
    45961 caaataagaa gaccattatt aattatatta atgtttgtgg tagctatatc atttatcatt
    46021 acaaataaca caaaaaacga cgaagaactt aatgataaga taataactat acaaggagtt
    46081 gtcaaaggaa aaattgaaaa gaaaagatac aatcagtaca aggtaggggt ttttctaata
    46141 aatgattata caaaaaataa aaatttgaag attggtcaga aagttaatat tacaggtaaa
    46201 ttcaaaagtt tagataaaat gaagtatgat gattttgatt atggaaggta tataaaaagt
    46261 actggatata aaggtatagt gtatataaat aactataaaa ttattgataa aaataaacgt
    46321 tactctttaa taggggaaat aaagttttat attagtaaaa cttataggta cttatataag
    46381 aaaaactcag attttataaa ttctatacta ttagcagaag ttgaaaattt gactgaggaa
    46441 caaaaagaaa tttttactag aactggaact agtcatgtaa tatctatatc aggtcttcat
    46501 acaggaatat tatgtgtaat tatatccttt ctattaagag gtataaataa attgtataaa
    46561 ttattaatac tgtcgatttt tataacttta tattgtataa tggtaggtgc gtctccatcc
    46621 ataattaggt ctatagcatt tgttatgatt ttttatttat caatatttat tgatagaaag
    46681 aaagatggaa tatcggcatt gtctctaatt gggataattt taattatgaa taacccctat
    46741 gttatatata atgtaagttt tcaattgtct tttttagcta cactttctat attaatattc
    46801 tataataaaa taaatagtat tataaaatta agtatggtat cattgacaat atcatcaaat
    46861 atattaactt tacctataat ttattataca tttaaaggta taccattgct ttcaattata
    46921 ggaaatttaa ttatagtact atttgtggga gtaataatgt atttaagtat tgcaagttta
    46981 atcgtattta aagtaagtgt agtaatagct aaaattatat ctttttttaa tagtacattg
    47041 atagaaagca tatttttttt actagaaaaa atcagcaatt taagttttgc atacattaat
    47101 atagaaaatc ctaaatttta tattgttgtt atttattaca taggagtgtt tttttacata
    47161 ttttacatag aaggaaaaga gataaaggag caagagaatg aattacaagg atattataag
    47221 gaatgtaaaa gagaaaaact ttgaaaaaat gtatcttttt tatggaagag agtattattt
    47281 aattgagaat gcaataaaag catttaaaga tagtctaaac gagggaatgc ttgattttaa
    47341 tttagatata atagatggga aggaaatagt cttaaatcag cttataagct ctatagaaac
    47401 acttccattt atggatgata ggaagatagt aataataaaa gactttgaac tattaaaagg
    47461 aaagaaaaag aattttacag atagtgatga gaaatactta atagagcatt tagacaatat
    47521 tccagacacc acaactatag tttttgttgt atatggagat gtagacaaaa gaaaatcatt
    47581 agttaagaaa ataggaaaca atggaattgt ttttgattgt gataagcttt ctgatatgga
    47641 tttgtttaaa tggataaaaa aatcttttgc tttaaatgat gttataatag ataattctca
    47701 aatcatgtat tttattgaac aagaaggata cagagataag agtagtgaaa agacattatc
    47761 tgatttagaa aatgaaataa ataaaataag ttcatttgtt ggtaaaggga ataatgtaac
    47821 caatgatgta attgataaat tatctcaaaa aaaagttgag aatgatatat tcaaattaat
    47881 cgattatatt ggagaacaaa atgcttctaa tgcaatgaaa atattaaatg atatgataca
    47941 agaaggcgaa tctgtattag gtatattttc tatgatagca agacaattta aaataattat
    48001 gcaagtaaga cagttacaac ttgatggata ttcaacaaaa cttatagctg ataaattaaa
    48061 aatgcatcaa tttgttgtag gaaaagcatt aaagcaaact aaaaattttt ctgatgatat
    48121 aattgtggaa atattaaact atatattaga aagtgattat aaaataaaga caggtcttat
    48181 aagagatact ttagcagttg aaatgttggt tagtagatac tgtaaaagag aagcaattta
    48241 aaaaatctat atattaataa aaaataaata gcaagatatg ttatagttca gagtagatgt
    48301 aagctaaatt aagtttgata tacaatcaac tataatatgt ctaactattt attttttatt
    48361 gtataaattt acaaaataaa aaacccctac ataggggtta ttatatataa gaaatataaa
    48421 ctggtaatta agcgttcata ccgtttaatt tttgagctaa tttagctact tttctagctg
    48481 cagcattctt atgtatagtt cctttagaag ctacttggta tattcttttt tgagcgtatt
    48541 ggaacttagc aacagcatcc tctctgtttc cagctgcaac agcatcttcg aatcttctta
    48601 ttgcagtttt tatttgagat tttctaactc tatttaaagc agttttcttt tcgataacac
    48661 ttattctttt cttagctgat tttatatttg ccaccgtgtt cacctccctg tattttttta
    48721 tcatattcat cgtcaacata ttagatttta acagaaataa atctaaaaat caaggattat
    48781 tatttatata ttttaataat gttttttatt ttgatttttt agactgtaaa ttgtgtataa
    48841 ataatttgca atatcttgtt tttaaattgg tatattttgt gttttaaata ttttgacata
    48901 tataattaat atttcatttt gtaacaaata tttgagataa tacaaactat taacatacat
    48961 tttgatagta tttccaataa ttataagata atacaagaaa ttactcattt ttgtaaattt
    49021 aatgaaaaat tataaaaata taaatttata tgcttaatta agataatttt tccaataatc
    49081 aagataattt ttttcattag tatgtatgat agatgcatca aacaatataa ctaatatgtt
    49141 agaaggttat atgtaattaa tgtcagtgtt tatatagaat agcatttgta gcatttatta
    49201 tagttgtaat tactatttat atcatagact tgaatagtct aaaaaaatag actataatat
    49261 ttttatagac taaagaaagg gctgataaga tggacatagc aaaactaatt ttaaatcctg
    49321 caaggcttcg tattttacaa tatattcgac tttatggcag tgttcgtaca tctgatattg
    49381 taaagtattt aaatgatatt cctcgtgcaa cagtttatca ccatgtaaaa attttagaag
    49441 agaacaatat gattgaagta attaaagaaa atcgtgtgcg tggtactatt gaaaaggttt
    49501 atgcactaaa ggaatataca acatctatgg aaggagagac attcgttgca ctttctacag
    49561 cattttatgt aggtctgatg caggaaatga atgaatactt tagcagaaaa gagcaagacc
    49621 ataaaaagga taatgtattt ttctcttcag cattactata tatgagtgat aatgaatatg
    49681 aaaatcttct taaaagtata gctgatttat tgaaaccata tatagaacaa aagcctaaat
    49741 caaatctaaa acttagaaaa ctttcaatta tatcttctcc acctgtagtt gataatgata
    49801 aaacaaaata acatgcaacc catttttata aaaggaggtt atatatgaaa tttcatgagt
    49861 ttggaaataa aaacagacca catattatgt tgattcatgg gggagggaat gcatggtgga
    49921 actatttgcg acaagcagaa gttttgtcta acaaatatca tgtgatactt cctacattgg
    49981 atggtcatgg agaagaatat gaaacaacat acatttctac agaggataca gcagataagt
    50041 tgatatcata tatagatgaa aattgcagtg gacatctttt cgctttgtgt ggggtatcac
    50101 ttggtggtca aattgtcatg gaacttttat ctcgaaaacc taatattact aaaaaagcaa
    50161 ttattgatgg tagtatttgc tacccaagac ctcttatggc aaggttttgt attgctggta
    50221 ttcgattttt tggaggactt ttgtttagtg agaaggcttg tcgctttcaa attgctatga
    50281 tgccaaaatt gttacctgaa aatatgcaat atccagatga aataaaagca tattatatga
    50341 cagatatgcc acatgtaaga aaagaaacat tctataatat gtatcgtact tacatgatga
    50401 actatacact taaagagaat gttaaaaaaa ccacagcaca agtaatgtac tggtatggag
    50461 aaaaagaaat gaaatgtgtt aaaaaatctg caaaaatgtt tcagtctcat gtgccctctt
    50521 gtgagattta tgaagctaaa ggttacaatc atggatattt atctctttat cttccagatg
    50581 aatggctgac aattgctgaa acattttttc atcaggaata aaggagtgag atacttatag
    50641 agtaatcgtt gcttcttctt agaaatgtag taaataaagg aggtatgata tgaaaaagag
    50701 tatattaatt ttagctattt ctggaatcat agtatcaact acaagtatgc cagtgatggc
    50761 tgaagtatct gatttaaaat atcaagtaaa ccagacagat actagaacag taacacaaac
    50821 taaaggtgat aataaaaaaa caaattatga ccctaagtat cccttaaaag gaatgttaga
    50881 acagcttggt cttaatacaa caggaaaatt tggatgggat attaattatg gtggaaatga
    50941 aaatgggcat gaacttagag cagatggcaa atattactat ataaataaag gatattcagg
    51001 attaggtgca tacgctgctg catttgcagg tgaaccatac aagagtataa tatttaaaaa
    51061 ccttgaccct ataaaaagta tagcaggcaa agagttgctt acttatgagc aagctaaaaa
    51121 tgaacttgca gtaattagaa atttcctaaa cagtttcgat tggagaaatg catctgatat
    51181 ggaaaaggcg aatagagctg caaaactggt aatagagtca aaatatgtga gtggtgtagc
    51241 acatgataca gatgtatatg gaaatattgt tgaaaaacgt ggttcatgtg gaagttttgc
    51301 aagtagtttt catgtattga cgaggctaat gggaatgaat tcgatatatc aggaagatgg
    51361 agccttaaac catgcttgga actatgttca aattgatggt aagtggtatg aatttgatgg
    51421 ttctgaagtt gcattatata gaacttcagc agagtttaat tcttctagac tagaaaatgc
    51481 aacaaaaact atgcctaagt actatgatgc taaggcgtta tttgcattag gtttcaacca
    51541 ataaaacaag aaaggtactt tagagaggct ttgtatgatt gaacatcttt aaatccttca
    51601 aaaagttaaa taaacacttt caaaaatatg tttatcattt aattatttta aaggaaatat
    51661 ataataaatg aaattatttt aaagaaaatg ataaatagat taaaaggtag cacctatata
    51721 aatagttgct acctttttct gtttgtaaat aaatgataga taagaaagtt tgctggcaaa
    51781 tcactgactg aacccaattt tcttacattg aaagccttaa ttttacttgt tttaaataaa
    51841 tttacaattt cttgttataa aatactaaat tttgttaaca attataatta gcatttaatt
    51901 tatactggag gtttatatga ttaatgtaag aacagattta gctttagaag ctagtgaaat
    51961 gtgtgaaaag tctcaagaag gaagtagtat tcctggtgta aaaatagaaa ctaaagaatt
    52021 agaaaattgc attgtaacta aagttgaagt aatagacgaa caaggctcag aaataatgaa
    52081 taaagatata ggaaaatata taactctgga aagtaatctt atgaagtttg atgatgacga
    52141 atcaagagaa gaaatgataa gttatctaaa agatgaatta gtagatatat ttggacaaga
    52201 cgaaaataaa aaaacactgg taattggtct tggaaataga aatattactt ctgatgcatt
    52261 aggaccaaaa agtgtatcca aaacacttgt aactagacat ctttttaaaa attataataa
    52321 agactatgat gatgatttca ctgaggtatc agctttaagc ccaggagtta tgggtgttac
    52381 tggaatagaa actagtgaaa tagtaaagtc attggttgag aaggttaagc cagatagagt
    52441 agtagcaata gatgcattgg cttcaagaaa aatggagaga gtaaactcta ctatacagat
    52501 atcaacagca ggaatatcac ctggtggagg tgttggcaat actagaaaat ctctaactaa
    52561 agaaacttta ggcgtggatg ttattgcaat aggcgttcca acggtggttg atgcagcaac
    52621 tcttacaata gatgtcttag atatggcaat agacaattta atagctcaat cagaagaaac
    52681 agaaagtttt tatgaaatgt tgaaaaaact taaagaagaa gaaaaatatc atctaataaa
    52741 agattcgtta gacccatatg acaagaactt aatagtaaca ccaaaggata tagatgatac
    52801 aatcgaaaat ctatctataa taataagtga aggcttaaat aggtctttac atccaggtag
    52861 attggtataa aataaggagg agcaattatg tttaaaaaat gcattaaagt agtaaccttg
    52921 acttttatat tagtatgcat tttaccagga aaatcattag ctttgaatca agatgatttt
    52981 ttaaagtttt tagtaaattc atcttatcca gaagctaaag tcgaaggaaa tgatacagaa
    53041 aataaaaaga ataataaaaa taaagaaaca agtaaggaaa ataaggaaga aagtaaagaa
    53101 ggaaacacta aatctaaaga tgcaagtaaa gttgataata aaaaagagag tgaaaaagaa
    53161 tatataaaac tttatgttgg taaagaaaat gttccagata ttgagtcaaa aaattcagac
    53221 acaactgaaa ctaacacaac atctagttca gattataagg atgatttaag agtaaccaaa
    53281 gaaaatccaa gaattttgat atatcatact catggatgtg agacttattc aaattcacct
    53341 gatggaaatt atcattcaag agataagaaa aattcagtaa tggaagtagg aagtgcatta
    53401 actagtgctt tagatagcaa aggatggggt gtagtccata ctactaaata ccatgactat
    53461 ccatcttata ataactctta tgcaagtagc ttaaaaacaa tacaaagtat attacctaaa
    53521 tataactcag tggatatagc gatagactta catagagatg ctagggattt aactaatcca
    53581 gccactaagg aaaaagacca tttaaaatat acaactatga taaatggaga gagagtatca
    53641 aagttcttct ttgttgtagg aggtaaaaat acaaatagaa aacaacttag agctttagca
    53701 gaagatataa ctgcttttgc tgagaaaaag tatcctggtc tagtatctcc aatagtagaa
    53761 aaagactatg ctagattcaa tcagtttgca gttaagaatc atatgttagt agaaataggg
    53821 aataacgcaa caagtgtaga agaatctaag gctactacaa agtatttagc cgagattttg
    53881 gatgaatatt ttaaacaaaa aaattagagc tttaagttac aattaggagc atgctaaatg
    53941 agccgattag aaaaaaatat agaaagtaaa agtaaactaa gaaaatacaa gtgtattatg
    54001 agaatcttat ttttgattac tatgattata ggcacatcag tttgtgtatt tatagtagac
    54061 agtaatgcaa aaagtatgct aggaatgaaa caatatgatt ttccaagtat taaatttgat
    54121 ataacaaaat ttgattttga cataccaaat tttgatatac atgaaatcat aaaaaaattt
    54181 aataagtagt aataagtgaa taaggtttat tgattaaaat aagccttatt ttagttatat
    54241 atttttaatg tataaaataa aaattcatta actgtatttt ataggattta ctttaagttt
    54301 acgatattat ataatattta gtgttagact tgataatcca catataatgt ggataatttt
    54361 gtttagtgcc aattagttta tattcaaaaa ttttaaattt ggtatataaa gagtttttag
    54421 ataatgtaaa ataataacta taagaataat caagaggagg gaattttaag gtggacaata
    54481 aacaaagtag aactagaaat tttagtataa ttgcacatat agaccatgga aagtctacct
    54541 tagctgatag attaatacaa caaactgggc ttgttagtga aagagacatg aaaagtcaat
    54601 tacttgacaa tatggacctt gaaagagaaa gaggaatcac tataaagctt caaaacataa
    54661 gattaatgta taaagcgaag gatggaaatg aatattattt aaatcttata gatacacctg
    54721 gacatgtaga ctttaactat gaggtatcaa gaagtttagc tgcatgtgaa ggagcactat
    54781 tagtagttga tgcagctcaa ggtgttgagg cacaaacttt agctaatgtt tatcttgcta
    54841 tagaccaaga tttagaaata ttaccaataa taaataaaat agatttacca agtgcaagac
    54901 cagaggaagt aaaaaatgaa atagaagatt taatagggct tgattcaagt gaagctcctc
    54961 ttatttcagc taaaactggt ttaaacatag aagatgtttt agaagatatt gtaaaaaatg
    55021 ttcctccacc taaaggagat aatgaagctc cattaaaggc attaatattc gattcttact
    55081 atgatgctta caaaggtgtt gtagcttatg ttagagtatt tgaaggaact gttaaaaagg
    55141 gtatgacaat aaaaatgatg aataccaata aaaagtttga ggtaactgaa gttggtgtta
    55201 tggctccagg tcaaactgaa cttagtgaat tatcagcagg tgatgttggt tatattgctg
    55261 ctagtataaa agatataaga agttgtcgtg ttggtgatac aataacagat tcaaataatc
    55321 ctacagaaga acctttacca ggatacaaaa aagctactcc aatggtatat tgtggtatat
    55381 atccaggaga aggagaaaag tatgagaatg ttagagatgc tcttgaaaag cttcaagtaa
    55441 atgatgctgc acttgaatat gaagctgaga cttcagcagc actaggattt ggttttagat
    55501 gtggtttctt aggtctttta catatggaga taatgcaaga aagacttgag agagaattta
    55561 accttgatat aattactaca gctccatctg ttatatatag agttacaaaa atggatggag
    55621 aggttgtaat gatacaaaat cctgcaaact taccagaacc atctgagata aagatgatag
    55681 aagagcctat agtaaaagga gatataatag ttcctaaaga ctatgtgggt gttgttatgg
    55741 agctttgtca ggaaagacgt ggaaatatgt taaatatgga atatatagat gagagaagag
    55801 taatgcttca ctatgacctt cctctcaatg aagttgttta cgatttcttt gatgctttaa
    55861 aatcaagaac tagaggttat ggttctcttg attatgaggt taaaggttat gtagcatcta
    55921 cacttgtaaa acttgatata ttaataaata aagagcaagt ggatgcactt agttttattg
    55981 tccatgagac acgtgctttc cctagaggaa aggcaatgtg tgagaaatta aaaggagaaa
    56041 ttccaagaca tcagtttgct ataccaatac aagctgctgt tggtaataag gttattgcaa
    56101 gagaaacaat aagcgctcta agaaaagatg ttcttgctaa atgttatggt ggagatatat
    56161 ctcgtaagaa gaaacttctt gaaaaacaaa aagaaggtaa gaagcgtatg agacaaattg
    56221 gttctgttga agttcctcaa aaagcattta tgtctgtgct taaattagat gagtaaatcc
    56281 ttataaattt agataaagat atttaaaagc tagagtgatt ttagaattat ttctaaatta
    56341 gtctagcttt tttatggtat attttaagta aactcataga gaatataagt aagaatatta
    56401 aagaagaata aaaaggtgat atttatgatt aatatagaaa ttcctaaaaa agtagactat
    56461 ataattaaag aattagaaaa gaatggttat gaagcttata tagttggagg atgcgttaga
    56521 gattgtttat tagaaagagt tccaaacgat tgggatataa caactagtgc tagaccagaa
    56581 gtggtattag aattatttga aaaaacaatt ccaactggta tacaacatgg gactgtaaca
    56641 gttatgattg aacatgaacc atttgaagtg acaacttata gaattgatgg aaattatagt
    56701 gatggtagac atccagattc aatagaattt acaaataaca tagttaagga cttgtcaaga
    56761 agagatttta ctatcaattc aattgcatac aattcaaaga caggattagt cgacccattt
    56821 aatggctatg aagatataca aaataagtat atacgttgtg ttggaaatcc agtagataga
    56881 tttgaagaag atgcacttag aatgcttaga gcagttagat tttcagcaca actcaatttt
    56941 aaaatagctg aagctactaa gcaaagtatt cataaaaaag cagatttgat aaaaaatgtt
    57001 tctattgaaa gaatccagac agagtttaat aaaatattag tatctgattc atctaaatta
    57061 aacttattaa aatcaacagg tttgttgaaa tttataattc ctgaaatatg tgaattagaa
    57121 gatgttactc aacacaatcc atatcacatc tatgatgtac aaaaacatac tttaatagct
    57181 acagaagtaa ttgaagatga actgtattta aaacttacaa tgttgtttca tgatttaggt
    57241 aaaaaagtaa ctaaaacaac tgataaaaat ggtgttgacc atttttatac tcatagtaga
    57301 gaatctgtaa agattgcaaa gaagattttg aaaagactta agtatgataa ttatactatt
    57361 aataaagttt taatattaat acaatatcat gattatagaa tagaacctaa aaggaagata
    57421 attaaaaagt tattaaataa acttgaagat gttggattat ttgaagattt aataaaagtt
    57481 aattgggctg atacacttgc aaaaaatcca aagtatgcaa aacaaaagat attaaatctt
    57541 attgagtgtg aaaaagaatt taaacatata ataaatcaaa aggagtgctt taatcttaaa
    57601 gatttagcta ttaatggaaa agatttgata tctataggta taaaaccagg taaagatata
    57661 ggatatattt taaataagat gcttgaaata gtcataaata atccagagtt aaatgaaaaa
    57721 gaaatactaa aagaaaaagc attaaatata tatacatttt agattcaaat ataaaaaatt
    57781 taattacttt aaaaaacata gaataaaata cttatttaga taaaataaat aatttttaga
    57841 gaatatttta gaagttacga ttgtatgatt tttaaatgca taggcattta ctctaggact
    57901 atagactaat ataaaaaaaa actttgggaa tactaaaacc ataaatttat aaaattaata
    57961 ttttatatac tgtaaaacag tgaggaggga cagtatgcat actcaactac aaaagactat
    58021 tggtctttca gcagctcttt ctactgttgt aggtatggtt ataggttcgg gagttttttt
    58081 taagccacaa gcaatataca ctacaactaa tggagctcca ggtttaggta ttatagcgtg
    58141 gcttttaggt ggttttataa caataactgc tgggcttaca gctacagaaa tttcagctgc
    58201 tataccaaaa actggtggta tgatgattta tatcgaagaa atatatggag aaaagttagg
    58261 ttttttaact ggatggatgc aaactgtatt atttttccca ggtacatcag cagcattagg
    58321 agtaatattt gctcaacaag catctgaact tttaggaatg agcccaaata atatggcaaa
    58381 tgtacttcct atagcaattg gagttatact atttttagca ttattaaata taataggttc
    58441 atccttagga ggaaaagttc agacagtagc cactattgga aagatgatac ctttaatttt
    58501 aataatagtt tttggattta ttaaaggtca aagtagtgaa gtattaaatc catttgtagg
    58561 agatggtgta aatgcatcaa atgcacttgg acaagtatta atagctactt tgtttgcata
    58621 tgatggttgg ataaatgttg gagccatatc aggagaaatg aagtctccag agaaagattt
    58681 accaagagca atagttggtg gtttatcatt agttatggca gtttatatta taataaatat
    58741 agcttatctt tgggtagtac cagcaagtga attagcaaca gttacttccc cagctacatt
    58801 agtagcaaca agattgtttg gaaatatagg tggaaaagta ataactgtgg gtatattaat
    58861 atcagtattt gggacattga atggatattt attaacaggt tcaaggatac cttatacatt
    58921 agctgaaatg ggaactttac cagcatctaa aactctttta aaagtaaatt ctggaggttc
    58981 tcctgtaaat tcaatactac ttataactgt gttagcctgt gtatatgcat tatctggtca
    59041 atttaatctt ttgacagact taacaatatt ttcaatatgg gtattttatg tattgacttt
    59101 tataggtgtt atgaggctta gaagacaaaa gccagattta cacagaccat ataaagtccc
    59161 tttatatcca ataataccaa ttatagctat attaggtgga ctgtttgtaa taataaatca
    59221 aatattgact tcaacagtca tatctttagg tggaatattt ataacactat taggtttacc
    59281 agtttattat tatatgaaaa aaagataact acttaattta agttagataa atttgggtaa
    59341 aggtgaaaat taacttttat ccaaattttt tatactgtta tacaatataa gtattatata
    59401 ttacttgatg tgctattttg tttgatttat aatttagtaa ttgatgtttt aagataattt
    59461 aagaaatgag gagtgaaaga tgctaggact ttatgtacat attccatttt gtgtgaaaaa
    59521 atgtaagtat tgtgatttta attcttataa aatggacata gattcaaaaa aaagatatat
    59581 agaagactta aaaatagaaa tggaattata tagtaataaa ttatataaag ataataaata
    59641 taaaaataaa gaatgctgta gtctaaataa aaatgacaaa ataacgagta tatttgtagg
    59701 gggaggtaca cctagtatac taacctctga tgaaataaga gaagtattta taagtataaa
    59761 agaaatgttt gatatagatg agaatgcaga aataactata gagtgtaatc ctgggacatt
    59821 aacattagaa aaattaaaaa ctatgaaaga gattggcata aatagactta gtatagggct
    59881 acaagctatt caagaaaagc atttgaactt tataggaaga atacatactt atgaagaatt
    59941 tgagaaaaac tataaagatg cattaagtgt aggttttaaa aatattaaca tagatttaat
    60001 gtacagtctt ccaaatcaaa ctctatgtga ttggaaggaa actcttgaaa aagttgtaca
    60061 cttaaatcca acacatatat cagcttattc ccttatacta gaagaaggaa ctgaactata
    60121 caatatgtat gaaagtaata aatttgaact tatagatgaa aatgtagata tagaaatgta
    60181 tgagtataca ataaactact taaagtcaaa aggatataat caatatgaaa tatcaaacta
    60241 ctcaaaagaa ggctataatt gtgagcataa tattttatat tgggaatgtg aacattatat
    60301 agggattgga gcaggagctt ctggctatat taatgagaac agatacaata atgtagaatc
    60361 tttagaagac tatcatttaa gtttggtaaa aagagaaaaa ccaatacaag aaaatgaaat
    60421 tctttctaag aaagatatga tagaagaaaa gatatttatg gggcttagaa tgaataaagg
    60481 cataaaattt gaagatttta aaaaaaaatt tggaatagat tttagagaga agtataataa
    60541 gcaaatagaa atgctattag ctagaaagct tataaatcag agctttgaag gtatacaatt
    60601 aactcaaaaa ggaagagaaa tatctaatag tgtatttata gaatttatgg aataattttt
    60661 aaggtgttga caaaataaat ttataatggt atataatata tataatcttt ttagcactcg
    60721 aacttagtga gtgctaacag ctaggaggta taataatatg gaattaaatg aaagaaaatt
    60781 aaatatcctc aaagctatag ttaaagatta tatagaaaca gctgaagcta taggttctag
    60841 aacaatatct aaaagacatg atttaggtgt tagtgctgct accataagaa atgaaatggc
    60901 tgaccttgaa gaattagggt atttaattca gcctcatact tctgcgggta gagttccatc
    60961 tgaaaaaggc tataagttat atgtaaactc tcttatgagt aaaagcgaat tggatgataa
    61021 tgataagatt cttattgaac aatgtatgaa tcacaatata aatcatataa aagaattgat
    61081 tcatgaaact tctaagctat tatcgcaact aacaaactat acaactgtag cagttactaa
    61141 gagtttaata aatcaaagtg ttataaagca catacagttg gttgctatga atgacaataa
    61201 tattttactt atagttgtaa cagataaagg ggatttaaaa aaagctaacc ttacaactaa
    61261 tgtatattta gatcaatcta agttaaattt gatttctgat aatcttacaa ggaagctctt
    61321 aggtaaaagt ataacagatt tggatgataa tctaattgct tttattaaat acgaaataag
    61381 tgagtattct gggcttatag atgagctttt aaatgctttg aactcaaata tgaaagaaga
    61441 agatttttct ctatcattaa atggagctac taacatattt agttatccag aatttaatga
    61501 tgtattaaaa gcaaagtcat ttttaaatat gttggaaaaa aaggaaacaa tagctgacat
    61561 aattaaatca aagggaatac aaaaagacaa tctaaatata ataattggta gtgataatga
    61621 ttgtgaactg gcacaggatt gtagtatagt tacagcaact tataatgtag atagagactt
    61681 ggttgggcga ataagcttta taggccctac cagaatggat tatgctagaa tttactctat
    61741 aataaattat atgagtttat taattaatag aaagtaaaga aattttaaat tgcgaggtgt
    61801 aaagtcttgg ataaaaaaaa tgagcaacag gaagtaagag aagaaaatga tacttctatt
    61861 aaccaagaat cggaaactca agtagagtta gaagaggaag ttgttaatga agaatgtgaa
    61921 acatcaagtg aaaaaactga tgaaaaagaa gttgatgatg aaaatgtaac agatataaat
    61981 tctaagttag cagaaaaaaa attgcaggat gagttggatg aattaaatga taaatatcaa
    62041 agacttcaag ccgaatatgc aaactacaga agaagaactc aacaagagaa agagacaata
    62101 ggcgtatttg caaatgaaaa aataataact gaattgatac cagttataga tagtatggaa
    62161 agagccttag atgcatgtga agataaggaa gatactatgt ataagggtat aagccttgta
    62221 cataaacaat taatagacac tttagtaaaa tttggagtag aagaaataga agcagaatct
    62281 aaggaatttg accctaatct acatctagca gttatgcaag aaagtgtaga tggagttgaa
    62341 gcaaatcaaa tagtaatggt acttcaaaaa ggatataagc taggaactaa agttgtaaga
    62401 ccttcaatgg ttaaagtttc ttgctaagta taaattaaag gttaaattat ttaacctaat
    62461 ataaaatatt aaaataagta aaacttaatt atataattac tcgaggagga ttttagtcat
    62521 gggaaaaata ataggaatag atttaggaac aacaaattca tgtgttgcag tgttagaagg
    62581 tggagaagca caaataatag caaatagtga aggtatgaga actactccat cagtagtagc
    62641 atttacaaaa gatggtgaaa gaatagttgg agaacctgca aaaagacaag cagttacaaa
    62701 tgcagataaa acaataactt ctataaaaac tcatatggga actgattata aagtaaatat
    62761 agatggaaaa tcatatactc cacaagaaat atcagcaata atattacaaa aattaaaatc
    62821 agatgcagaa agttacttag gacaaacagt aacagaagca gttataacag taccagctta
    62881 ctttacagat gctcaaagac aagcaactaa agatgctggt agaatagcag ggcttgatgt
    62941 taagagaata ataaatgagc caacagcagc agctcttgct tatggtatgg ataaattaga
    63001 ccaagaaaag aaaatattag tatttgactt aggtggagga acttttgacg tatctatact
    63061 tgaaatagga gatggaactt ttgaagtttt agctacagct ggtaacaata gattaggtgg
    63121 agatgacttt gaccaaatag taatagatta tttagcagag gaatttaaaa aagctgaagg
    63181 tgtagattta agaaatgata aaatggctct tcaaagatta aaagaagcag cagaaaaggc
    63241 taagaaagaa ttatcatcaa caatgagttc aaacataaac ttacctttca taactgctac
    63301 agcagaagga ccaaaacact taaatataga tttatcaaga gctaaatttg aagaattaac
    63361 tagaggttta gttgaaaaaa ctatggaacc aactaagaca gctttacaag atgcaggact
    63421 ttctacaggt gatatagatg atgtattatt agtaggtggt tctacaagaa taccagcagt
    63481 acaagaagct gttaagaagt ttataggaaa agaacctcat aaaggtataa acccagatga
    63541 gtgtgttgca gcaggtgctt ctatacaagc tggagtttta gcaggggatg ttaaagactt
    63601 attattacta gatgttactc cattatctct tggtatagaa actatgggta atgtaatgac
    63661 taagataata gaaagaaata ctacaatacc aactaagaag tctcaaatat tctcaactgc
    63721 tgctgataac caaacagctg ttgatataca tgttcttcaa ggtgaaagaa gtatggctta
    63781 tgacaataca actttaggaa gattccaatt aacagatata ccaccagcac aaagaggaat
    63841 acctcaaata gaagttactt ttgatataga tgcaaatggt atagttaatg tttcagctaa
    63901 agatttaggt acaggaaaag agcaaaaaat aactataaca tcaaacacta atttatcaga
    63961 agcagaaata gagcaaaaga taaaagaagc agaaatgaat gcagaagctg acaaacaaaa
    64021 gaaagaaaaa atagaagcat tcaatcaagc tgaatctact atatatcaaa ctgaaaaaac
    64081 tttaaatgaa cttggagata aaataagttc aggtgaaaaa gaggatatag aaaaagctat
    64141 agcagattta aaagctgtaa aagataatca agatgctaca gcagaagaac ttaagaaagc
    64201 tacagatgaa gtaatgacta agttccaaaa agtatctcaa gaaatgtacc aaaaagcagc
    64261 tcaagaacaa caagcggcac aaggtgcaga acaagcacaa gacaatggac ctaaagatga
    64321 caatgtagta gatgctgact ttaaagaagt agatgaagat aaataagcta tataatatgt
    64381 aacactaaat gataattgga acatatatga tttgtgaaaa tcatatagat gttaaagata
    64441 tatggacaat atacatcata aagaatataa tatatcatag attatataac ttaaagtaga
    64501 atataagaat taatgatagc ttgtagttta ttattctaca agctatcgtt ttgtaaaatg
    64561 aaggtggtgt caatttttga gtacaaaaag ggattattat gaagtcttag gtatcagtaa
    64621 aggtgcagaa gctcaagaga taaaaaaagc ttatagaaaa ttagcaatga agtaccatcc
    64681 agatagaaac cctggagata aagaggcaga agaaaaattt aaagagataa atgaagctta
    64741 tgaagttcta tctgatgata caaagagaaa aacttatgac cagtttggac atgatgggct
    64801 aaatggtcaa ggcggttttg gtggtcaagg aggatttggc ggtcaaggct ttggtggttt
    64861 tgaagatatg ttcggagata tatttggtga catgtttgga ggaagcttcg gaggtggaag
    64921 agcaagaaga agagggccac aacgtggtgc agatataaga cagagtgtta ctatatcttt
    64981 tgaagaagct gcatttggta aaaagatgtc tataaaagta aatagaagtg aagaatgtga
    65041 agaatgtaat ggaactggag caaaaccagg aacatcaaag aaaacttgtt caacttgtaa
    65101 tggaactggt caagttagaa ctgttcaaag aactccattt ggtaatatag caagttcaag
    65161 accatgtagt gcttgtaatg gaactggaga agtgattgaa tctccatgta gtaaatgtca
    65221 tggaactgga aatacaagaa aagttaagac tatagaagta gatatacctg ctggtataga
    65281 tgatggtcaa atgataaaac tttctggtca aggtgaggta ggagaaaaag gtgctccaag
    65341 aggagactta tatattgtag ttaatgttaa gtcacatcca ctatttacta gagatggaaa
    65401 tgatatttat tttgaaatgc caattacatt tgttcaagca actttaggtg atgagataga
    65461 agtacctact ttggatggaa aagttaaata tagtgtgcca gaggggacac aaactggaac
    65521 tgtatttaga cttaaagaga aaggaatccc tagaattaga ggtaattcaa gaggagacca
    65581 atatgttaag gttgtagttg aaattcctaa aaaattaaac gataagcaaa aagaactatt
    65641 gagagaattt gcgaaggagt gtgggtcgaa cgtccacgaa aagaagaaaa ccttcggaca
    65701 aaagatagaa gatatgttta agaaaaagta gttaaagtag ccaatatata atcatatttt
    65761 tgaaatctta gttatttata agattgtcaa aggagatatt atgattttta tattggctat
    65821 ttttgtataa aaaataaatg tgcataaaat aaaactgaat ataaataatt ttctgaaaaa
    65881 tacttgtcct aaaatatata atgtgctata atataatcaa ataaaagaaa ggggtgattc
    65941 cagtgggaac ggatgtggca ctgccaaatg atgaagaaaa ctttattgta atatacaaaa
    66001 taaaattaga tacttttagt gctagattaa gtactggaaa aactcatgag ctgggataat
    66061 tattgtaatt acctagactc aaacttttag tagtaaaata gtaatattat atagacaagg
    66121 tatctaattt ttaaatcttt tgtatgaatt aaaattttta taaagggtat atctgattag
    66181 aatgtaatta gggaaaccta gttgtgaatt acttttagta tatacatgtg taaagaaata
    66241 tgtatatggt attggttatt gtactagatg tgtatgtaaa ggaatatgtg tctagttggg
    66301 tatatgtaaa gaaatatact tataatctat gaaaaatttt tagtataaat tgctaaaaca
    66361 ttgagattgt tttttataga aagttagttt ataccaacta aaaatgtgct taagatttgt
    66421 ttgatgttta attataaata aggttgtaga taaaaaaata agtaaagaca aaggtttaaa
    66481 atacttgctt taaatatagt ttgttttgaa cacttgccaa attaaaataa ttaataaaat
    66541 agacatcttc tcatagtaaa atatactgtg agaggatgtt tttgctttgt tcataaactt
    66601 ttatgaaaaa tttgcatagt gtcacatttt aatatactat atatataata aaatatagat
    66661 aaaattaaat gattcaaaag agaaaggtga aaagagatgt attatatagg tgtagacata
    66721 ggaggaacag gtatacaagc aggagtagtt gataactatg ggaaaataat ttttaggtca
    66781 gagtgtaaaa cagtaattga aaaaggcttt gaaggaatac ttaatgacat aaaaataatg
    66841 atttataagt tgttggaaga taataaactt actatgagtg acataaaatc tattggattt
    66901 ggtgttccag gttttataaa taaagaagga ttagtaactt gtgtaaattt aaaatggaat
    66961 aaaaaagctt ttaataaaga gttaaaaaga agatttccag atgttgaaat tcatggagaa
    67021 aatgatgcaa cagtagcagc acttggagaa gcaaagtttg gaagtatgaa aggtgctaat
    67081 gttggagtat tatatacttt aggaactggt gtaggtggag gaatagtaat taatcaaaaa
    67141 gtcttttctg gagcacatgg attgggttca gaaataggtc atcaaattat aggagaaaac
    67201 tattttaatt gtaattgtgg aaataatggt tgtgtagaaa ctttttgttc agcaactgca
    67261 attataaagt attctcaaaa actgatagaa gaaggagaaa agagtaggat tttagatttg
    67321 gcagagggaa atttagaaaa tgtaaatgca aagatggtgt ttgatgcata tagagaaaat
    67381 gatttagtgg caattaaagt aataaataga tttaaagagt atttagcaaa aacttttgca
    67441 aacacaataa attctttaga cccagaaatt atatctatag gaggaggcat ttctaaatct
    67501 agcgatataa tacttgatgg aatagaagat ttggtaagaa aatttgtatt atacaaaaca
    67561 gaagatatag ctacaattac atgtgcaact ttaggttcag acgcaggaat tataggagca
    67621 gcttttttat aatgtaaatg aactgcttat tggaggcgtg atgatatatg ggtaaaacaa
    67681 atgctagaag aacgcttttt ttgatagcaa taggttcagg aactatgctg aatcctctta
    67741 attcttctat gatttcactt gctttacata gtatacaaaa tgattttcat attagtttta
    67801 caactgtatc ttggattgtt tcagcatttt acctagctag tgctattgca caaccagttt
    67861 caggtaagat aggagattta ataggtagaa aggtcttatt tttgagtggt ttgatgcttg
    67921 taattttatc agcatccata gtaccacttg ttcaatcatt ctttatattg atttttataa
    67981 gagtaattca agcaattgga acaagtaccc tatatccatc tggagttgct cttatacaaa
    68041 ataatataaa agaaagacaa tcttctgcat tagcagttct aaccattttt gcttcaacta
    68101 cagcaggatt aggtccgaca cttggaggat tattgttgga cttaggagga tggcatgcta
    68161 tatttcttgt aaatatacct gttgttttgg tttctatatg cttagggtat tttttattcc
    68221 caaaagaagt aaaagaaaag aaatctataa aagaaacttt aaaaaatgtt ttgtcaagat
    68281 tagatattat tggcatactt ctattttcaa ttgcaatgat ttttatatta ctatttttgc
    68341 tatctatgaa ggagtctttt aacttagaac aacttgtatt tggtataata ctgatgtgtc
    68401 tttttatttg gcatgaattg agaacaaaat tgccatttat agatattaag ctttttgtaa
    68461 gtaatcctaa attgtcaaaa gtttacttgc aatttattat attaaatttc tttaattata
    68521 ttttgttttt tggtcttcct agttattttc aagatgcctt acattatagt gcaaagtcga
    68581 ctggattatt tatgctattt atgtctggta taggtatatt tatatctcca ttaactggaa
    68641 aatggataga taaatctgga actaggtttc ctcttgttac atcatcaatc tttatgttta
    68701 ttagtgcagt acttctttca gtagttttta tccatatacc tgtaatagga aagggtatta
    68761 tattatcatt agcaggtatt agttatggag ttggtaatgt agccctgcaa tcctctatgt
    68821 ttgaagaaag tcctcgtgac agtataggga cagcttctgg tctgtttcaa actagtcgtt
    68881 atttaggttc tattttagca actgttttac ttggaatggt atttgaagta aatataacat
    68941 cagaacaatt tcagatatta ggttatgtta tggtggtctt aggtacaata agttttttat
    69001 taaattttat attaaagaaa gaattaagaa aagtagaata gtggatttat ggatttaata
    69061 agtctaataa ctgataagtt taaaaatatt gtttgtaaaa cataactggt ttgatattta
    69121 ttaattctaa gttttgaagc atagagtact cgataagtat acaatatttt gaattaaaat
    69181 taagcagaaa tttgaactag tctttcaaat ctctgcttaa tttagtggtt aaattttttt
    69241 atagagaaaa taagatttga cacttagata aaaaatcatt gcattttcaa aattctttaa
    69301 atcaaaccca agtatctcat taatcttttc taatctatat actagcgtgt ttctatgtaa
    69361 aaacatacta gtagatgtct tagaaatatt taaatcatta tttataaatt ttattcctgt
    69421 atatagaagt tcttcatcaa tagatttaat cttattaaaa tctattaatt tattgagtat
    69481 attatcctca ttaattaaat ctaaagtttt atatctaata aggtcaaaca aatttaaaaa
    69541 cttattttca gcgttgtctt ttataatatg aggtagtaaa tcagaacata actgtaatct
    69601 aaaatcaaaa tcagctttac tatctaattc accaagataa aaaatataag tactttgata
    69661 agtttcagtt tcaattatat tttgtgtagt tacattaata tctaagttat atttagaatt
    69721 tactataaaa aaaccattgt gttgtattat atttatatct tcaaataaat tataaaaaat
    69781 attttttaga tattcaaagt ctatatgaga ttggtaaatt aaataaaagt tgccttttaa
    69841 attatcgaga ttatttttat ctagaaaatc aataacataa atagcattat tgaaagtaac
    69901 taaatggcta ctagcatcta acttttggtt ttcatatgga tagatattta tttttttatt
    69961 aagctgtctt tctaaaaaat cttttaactc ttccataaag tctccttaaa aataagatta
    70021 tattcttatc ttatagctaa agtagtttct ttgtcaaata tgtgtattct acttctgtca
    70081 actgaaagtg ttaagtcatc accaacatta attctgtttt tactgtcaaa tctaattgtt
    70141 atcgtatttt cgcctagttt taagtgagca taagtttctg ctcccataag ttcttttatt
    70201 tcaattcttg atttaaaaca agtatctgga ttagatttaa taaaagtatc ttctacatga
    70261 atatcttctg gtctgatacc tataacaact tcattattaa tataattgtc ttttattaaa
    70321 tcatagtgtt tttctttatt caatttaagc ttaatatgtt cattttgtgc ataaatttca
    70381 tcattttctt ctattaatat tacatcaata aaattcatct gtggtgctcc aataaatcct
    70441 gcaacaaata tattagctgg ataatcgtat acatcttgtg gagttgcaat ctgctgaacc
    70501 actccatcct tcattactac gattctatca gccatagtca tagcttcaac ttggtcgtgt
    70561 gttacataga taaatgtagt tccaagctgt tggtgtagct tagttatctc tgttctcata
    70621 gcagttctaa gttttgcatc taagttggat agaggttcat ccattaagaa taccttagga
    70681 tttctaacta ttgcacgtcc taaggcaacc ctttgtcttt gtcctccaga taatgtttta
    70741 ggttttttat ttaaaagagg tagtaagtct aatattttag cagcttcttt aacttttttg
    70801 tctatttcat ctttaggcaa ttttctaagt ttaagtgcaa atgccatatt ttcgtaaaca
    70861 gataagtggg gatataaagc atagttttga aaaaccatag ctatatctct atcttttggt
    70921 tctatattat tgacaagttt atctccaatg tatagttctc cttcagagat ttcttcaaga
    70981 ccagcaatca ttctaagtgt agtcgattta ccacaaccag atggtcctac taaaacgata
    71041 aattctttat ctttaatgtc tatatttata ttttttactg cgttaaatcc atttgagtaa
    71101 agttttgata tattttttaa aattacttct gacataatat cctccttgat atttaaattt
    71161 taattatata gtatcaaatt tttttattat attaaatgtg taaaatgact aaatgtattt
    71221 gtttaatatg tatatttagt ttttagcaaa gaataaaact aacagtaaaa tatatttaaa
    71281 aaattaaaaa acaaaattaa atttattatc aaaaaatcat tttatgatat gttttatttt
    71341 tatattacaa atagagaata atgaattata ctagaaagta ggaggtgaaa atatgagcag
    71401 aatttcaatt tttatggaat catgtaatgg caaatttcca aatgaaaatt caatgttgtc
    71461 agtttccttt ataaaaaata ttttaaatgc agaaaacaaa gattttgcta aaaacatatt
    71521 taactatggg gaagaaagaa aaaacaataa gcaaataaag gatataaata cagccattta
    71581 cataccaaat cttataagaa gcaaaaatga gttacttgtt gatggagata taatattcaa
    71641 tataagtttt tataattatt ctatgttcag taaattatac aatggaattt taaaagtaaa
    71701 ggagctagaa tataaaggtt atagatttaa aataaaaaat ataaaaatac ataaagaaca
    71761 cgagataaaa gaaaatggtg ttatatttaa aactatgtct cctataatag taaagaataa
    71821 agaaggtaaa tatttagatg tagaagattc aaattatata gaatgtttaa actatatagc
    71881 taatctaact ctggagagta taagaggtag tgggcttaga aagccattgg aatttatacc
    71941 tattaacttc aaaaaaagag tgttaaaaga aaagattcgt ggatttaaag tgagagaata
    72001 ttactatata aatgcttatg caggaacatt ttttttaaaa ggagatatgg aagatttaaa
    72061 tgcactgtat aaaatgggaa ttggatatag aaggacagaa aatgcaggaa tggttgatat
    72121 attaaagtag cgaggtgaga gaaataaaag ctaaatttta tagatcaggt gatattgtaa
    72181 gagatattgg cattgtttac ttttatgaat tactaatgga tttaaaaaac gaactagaaa
    72241 aaaatgatta taagctaaaa tttacttgtg agttaaatag aaattattta tctttagaat
    72301 ctgcagaata tatagaccct aagtatatat ctgattatat attagaaaat caacttttta
    72361 aggtatttaa aaatgggaaa aaggaaacct tagaaaaaat atttagtaat atagataatt
    72421 taatgtatgt aaattttatt gaagaattgg ataaatcttc tgcaactgct aaacaaaagg
    72481 aagatattaa aaaagatttt aaaaacagga ggtttccata tgttagaaat agtggtaagt
    72541 atggattaaa cacgagttta aaaaatatgg aaacaaatgt aaaaagaata gtagatactg
    72601 taattaaatc aaatatagag atagatgaaa tagataaact tgatttgaca caatatgaag
    72661 aaaaagatag tgtatgtaat gtttgtaata taaataaaac aacaaaacta gatattgatt
    72721 taagagagcg aaaggactct aagtataact ttttatttag aggtgcagaa aaatcaggct
    72781 ttaaaagaag tggacaagtt gaaagtaata tttgttttga gtgtgaattt ttcaacttaa
    72841 tgtgtctttt atatataaat ttaaaaagac caatggtttt tgcatatacg aatgatttaa
    72901 gggaattagc atttttaaat cataagataa tgcttaaaag aaagatgtat tcagataaat
    72961 cattttataa aaaacttttg catgaaaaaa taagttcaat tagactatat aggtttgata
    73021 ttgatacgaa taaaggtata attctaaagt ttgattctat tatagagtat aaagaattat
    73081 taaaaaaaat tgaacttata gatattatag ataattataa tttttcaaga gagccaggta
    73141 atactagaaa tttgggtaaa agaatgattg ataatgggaa tttatcaaat ttaaaagaat
    73201 tattacttga taatataagt gttttaaagc aatcaactgg aacttctcga gaaatggatt
    73261 ttgtatctag ctcatataat atcggtttat atataaaatt gtgttggatt gtagatggag
    73321 gggaggagta taaaatgaaa aactatatgg aaagtaattt aatatattca agagtaggta
    73381 aagacttatt taataaaatg acagatgaat ccagaagaaa aaatttttct atgaaagtga
    73441 ttcaactact taagtctaat gatagaactc agctatttca aactataatg catgtgttag
    73501 tttctaatgg aatcttaata ggagaagggt ttgtagaagg tctaatgcag agttctgaat
    73561 tagaattaaa tacgaatgta ggtctattta ttcaagaaat catgaaataa aaaaggggga
    73621 aaatttaaaa tgaatgaaaa aagagtaaaa ggagtaacat taactatact gacagaaagc
    73681 ccagttccac tttcatatga ccaagggtat ggaaattata caccaataaa aaaagaacaa
    73741 tatagagaaa aaatacatgc aaaaactagt atagccacaa taacatatga tttaagaaga
    73801 atgctccacc aagaatatgg ttggaattta agtaatattg tttttggaaa aaaaggaaat
    73861 atatatccat ctattaagaa aaatgtagga tgtgtagatg aaaatggatt agagactgat
    73921 gtatttggtt atttaatacc acttaaagat aaaggttcta taagtaaagc ttctccactt
    73981 agaataatac cttttaggtc attaaatcca tataaaggtt caacacagct aataacaaat
    74041 agaggctttt taagtagtga atttggtaga aaatattatg atgagaagga agaaaatgaa
    74101 gtacctagag atgaaaactt tccaacatca caagcattag caatagaaga gactttatca
    74161 gattactacg tttatacaat aacattggag cttgatagaa taggagtagt agaagtagaa
    74221 gatggaaagt tacttttacc agaagaaaga aaatttatga gtaaggagtt aagagaaaaa
    74281 gcagtaaaag atatattaga tgcaattact gtgtttacaa gaaacataaa acattcatca
    74341 gtactattaa aaccacttgc agtaataggt ggagcttttg ataaagttgt accatttttt
    74401 tgggatgatg tagattataa tgctgatagt ggtgagataa atttagaggg agtcatagaa
    74461 actatagaaa gttatagcct taaagaaagt aacacaatac ttgctatcaa tgatagatta
    74521 aaaatttcta ataaaaagga attaaataag tttaatttaa gtaaataccc tgtaaaagag
    74581 attaaaaatc tagcagatag attggaaatt ggagaagata atatgtggta tttaaaagag
    74641 taggaggttt tttgaattat gaaagtatta caatgtaaac ttaagcaacc aactgctcac
    74701 tatagagacc caaaagtatt tcaaaatgaa tatataagta ctttaaattt accatctaag
    74761 accacaataa tgggaatgat aacgtattta tgtgatagaa gattaaactc tgatatagat
    74821 ataggaataa ttggaacaca tcatcataga gaactagaat tttcaagagg agagaacatt
    74881 gatttttgga atgaatatac aaatatgaga aaaggcaaag ataaagaaaa gtttttgctt
    74941 caaggaaact actatgatta ctataaagaa cataaagctc aaaatagcat attaaactat
    75001 gaagttctta aagaagtaga actgactata tttatttctt gcaaggatga tgaagaactt
    75061 gaatttatta gaaaaaagct tgaaagtcca tgtaaatatg caaatttagg aagaaaagaa
    75121 gattttgcaa taccaagtga aaaagggtgt tttgtgaaag aagttgagtt aaaagaggtt
    75181 atacctatga atactcgtga tgctataaaa gaaaatataa aattaaagaa tacatatgta
    75241 agagttgact taagagataa agagaatgtc gagactataa taaatcaagg tgtattgatt
    75301 gcattacctc ataaatataa agatttagaa gcaaatagag atgatagagt ttatgagttt
    75361 tgtcattata tatatgttga taatgatggt atatatccta aaaatattaa ggtaaatgta
    75421 tgtattgata caaaagaagt ttttacatgg ctttaaatta ttttgaaaga taggtgttta
    75481 tcatgaaaaa tatcatgcaa aaagaaatat tagctaagtc atacaattta agaactaatc
    75541 aacaagaaca aacattagtt gaacatatta aggatttatt tgaagtatta gaatctatat
    75601 tagaactaaa tctatattca gataaagatg tagagatact aaaaatatgt tgtgctttgc
    75661 acgatttagg aaaaattaat tcaattatgc aacaaaaaat ggagattaat aataaaatat
    75721 cgtatagttg ctcagaagaa gagaggaaaa agttagagtc tgacaaaaaa tctttaaaaa
    75781 agatagcaag acataatata ttttctggag catttttaaa agatatatta gaaaaaatga
    75841 acttgtcaga agaagataag ttatatatat ataaaagtat aatgttacat catggaaact
    75901 atgaagatta tatgaggtta agtattagta aagttcaaga agaaatttat gagtatattg
    75961 aaaaaggcat tttagaaaaa gaagagttta atctgaaaga tatagaaagt tatataaata
    76021 gcattttaaa tgtagacttt aaatttggtg aagatgtatt ggattatgat tacatagata
    76081 aattaagtga aagtatgttt atagacagtg attataacaa tggtcaaata gatgattcag
    76141 ttttaaatta tagaaagttt aagtatattt tatataaagg gatgctgaac ttaatagacc
    76201 atagtgcatc aagtagacag aaaggtataa aattttataa cgattttact gatgaagaaa
    76261 ttgataatat gattttaaat gagatatata agagtcaggg taatttagaa aaaaataata
    76321 tagagttcaa tactatacaa aaaaggttga gagaactttc tggaagaaat gttctgactg
    76381 ttgcatttac aggttcagga aaaacagctg cagattatag aaagactttt aaaagaaaat
    76441 tctttttagt gccaaataaa atatcagcag aaagttttta tagaaaaaat atttttcaaa
    76501 ataaaaatga tttagataca agaagtagta atgattacat tggattactt catggagata
    76561 taaacttata ttcagagaat gaagataatg gagaacatga ttttgtattg acattaaggg
    76621 atatagattt gagtataaac ttttgtaaac cttgtgtaat tgcaacagtt gaccagttat
    76681 tacttagtat gtttaaattt ccgggatatg aaaaaatatt cgcagccgta aaaaatgcat
    76741 ctataactgt tgatgaagta catttattgg aaccaaagat gtttttgatt ttgatatatt
    76801 ttatgcagtt tgcatgcaag tacttagata ttgattttca cttaatgaca gctacacttc
    76861 caaaatcata taaagagcaa atgataaata agggaattat ttttcaagaa gaaagtaatg
    76921 aaaatgttac tgataaagga gaaatagttt ttattgagag caacaaggaa gaagagattt
    76981 gtgaagggaa agatgtaaag gtttctttta taaaggaaaa agaaatcaag tcaatagttg
    77041 aagatgcttt agaaaataaa caaaaaattc ttataataaa gaatactatt gattcagtca
    77101 atagaacata tgagttttta aaagaaaatt tatctgataa gtatggtggt gtagatatag
    77161 atgttttaca tagtagattt aagttcaaag ataaaaaaga gaaatatagt aaaatattaa
    77221 atggagaggg tgatatttgg atatcaactc aatcagtaga aatatccttg gatttggatt
    77281 tcaatataat aataagtgat ttagcaacta tggatagctt gatacaaaga atgggtagat
    77341 gcaatagaaa taataagtat gaatatggaa acttttatat tctacctagt gaagataaaa
    77401 tttatgataa caaacttaag aacacaacta aaaacatctt aaaggacata ttaaaaacta
    77461 actctatttt tacaatggga attagaaaaa ctattttgga tgattactat gataatagtg
    77521 tagtcaaaaa atattttgaa gagaatttta taagttgtga taaagaaatt aagaatattt
    77581 atggtgtaaa taaagaaatt tttgatggat tggatttaat ttttaatttt gaaccttaca
    77641 aaaatattgt tgatagtaag aaggaagcag ctaaaatttt tagagatgtt gatgttagtt
    77701 acaaaattat tctggaagaa gatttttata aggaagatag agagttacaa caagattcga
    77761 ttcaagtatc agggtttata tttaatagat tatattatta tgggttaata agcaaagtag
    77821 aaggatacat ggtactaaaa tctagtagta agtttgagta taatagtact gtaggcttaa
    77881 ttttgaagtg agcatatgtt taaatataat atacctttag acattgaaaa tacaaaaagt
    77941 actactgtaa gtccactgta aaaactattt tttaaaagga aaaataagtt gtgagataga
    78001 gtgtttacaa gtgtatatag ataataaatt tgaggtttaa gattaactaa gtgggtttca
    78061 ggtttgatgg aaataaaata ataatagaaa aaatagaggg tttaagatta actaagtggg
    78121 tttcaggtac atagcaaaaa taattataag ttggagattt tgtatgttta agattaacta
    78181 agtggatttc aaatattgat atagtagata taatagaagt tttattatta ggtttaaaat
    78241 taactaatcg gatttttaaa tattctgact attgtataag gatattatta gcttgaattt
    78301 aaaaccaata atataaaaca acaaaatatt atatttatga tataataaaa gttatggaaa
    78361 aacaggaata ttactataga gaagagaggt aaacttatga ataattggat agaagtaact
    78421 ataaaaacaa caacagaagc agttgaacct ataacgaata tactatatga acaaggagct
    78481 ggaggagctg taatagaaga cccaaaagac tttttattcc aaaagaaaaa tgaactagac
    78541 tgggattatg ttgaagaaga agtatttaaa aagaatgaag aagatgatgt tcttataaaa
    78601 acttatgttt ctgaagaaaa aaatgtgatg gaatttgtcg aaataataaa gcaaaaagtt
    78661 ttaggattaa aagattttgg tatagatata ggtgaaggaa gtgtatcatt ggaccaagta
    78721 aatgaagctg attgggcaaa tgcatggaaa gcatactaca aaccaacaaa agtaggacaa
    78781 agggtagtag taaagcctac atgggaagat tatgctatgc aagaggggga tttaatcata
    78841 gagcttgacc ctggaatggc atttggtaca ggtacacatg agactactag tatgtgcatt
    78901 agagaattag aaaagtacgt gaataaagat tctaaagtat ttgatattgg ctgtggtagt
    78961 ggaatccttg caatagcagc agctaaatta ggagcaaaag aagttgtagc tgtagattta
    79021 gatgaagtgg ctgtaaaagt tgcaaaagaa aatgttcttg aaaataaagt tgaaaaaagt
    79081 gtatctgtaa tgcatggtaa tttaactgat gtaataaaag ataaagcgga tgtaatagtt
    79141 gcaaatataa tagctgatat aataaagata cttgcaaaag atgttcaaaa ctttatgaaa
    79201 gaagatgcta tatttatatc ttcaggtata attttggata aagtagaaga agttaaagaa
    79261 agcttaattg aaaatggatt tgaaatagtt gaagttcaaa aattaggtga atggtcagca
    79321 atagtttcta agcttaaaaa ataagggata tggtgacgta taatggatag attttttgtt
    79381 gaaaaaaata atataaatct acaagataaa acttgcacta tagaaggtga agatgtaaaa
    79441 catatttcaa aagttttaag atgcaaatta ggtgagaaac ttgaaatatg tgacaagaat
    79501 aataatgagt atatttgtga gataatgaat atagataaga gtatagttaa tttagaaatt
    79561 ttagaaaaag ttgatataaa tagagaatca gaacttaaag taaggctata ccagggactt
    79621 ccaaaagctc caaaaatgga aatgatactt caaaaattaa ctgaagtggg tgtagaagaa
    79681 ataatattag ttcaaactaa gagaagtgtt gttaaagttg atgacaaaaa agaagataaa
    79741 aaatttgaac gttgggaaag aataatttat gaagcagcaa agcaaagcaa aagaggtaag
    79801 ataccaaaat taagaggtgt tttaagtttt aaagaagctt tagaagatat gaaaaaaaat
    79861 aatgtaaata tttgccctta tgaaaatgaa agaacagttt caataaaaca tgcactaaaa
    79921 aaatgtgatt ctaatataga tagtgttgga atttttatag gtccagaagg tggattttct
    79981 gaagaagaaa tagaacaaat acaaaaaaat aattgtaatg ttgtatcatt ggggcctaga
    80041 atattaagaa ctgagacagc ttctgttgta gcatcaacaa tagctttgta tgaactaagt
    80101 gatttaggag gagaaaaata aattgaaaaa agtagctttt tatacacttg ggtgtaaagt
    80161 taatcaatat gaaacagaag ctatgctaga actatttgag aaagatggtt atgaacaagt
    80221 caatagtgaa gagtatgctg atgtttatgt tataaataca tgtacagtta ctcatatgag
    80281 tgatagaaaa tctcgtcaat atataagacg agttaaaaag aagaatccag atgcaataat
    80341 agccgttgta ggatgttatt ctcaggtatc tccggaagaa attttggata tagaagaagt
    80401 aaatttagtc atgggtacaa atgatagaag aaagattgtt gaagaaatta aaaatataaa
    80461 ttcaagtaag aaagttagta cagttgatga cataatgaaa gttaaagctt ttgaagaaat
    80521 agaaatcagc caaactaatg gaaagactag agcatttatg aaaatacaag atggatgtga
    80581 cagattttgt acttattgta tcattcctta tgcccgagga cgcgttagaa gtagagatat
    80641 tgatagtata gtcgatgaag taaaaaaatt ggctaataat ggctataaag aggttgtatt
    80701 aacaggaata catgttgcct cttatggaaa agatttaaag gatagggata ttaaacttct
    80761 tgatgtaata aaacaaataa accagataga aaaaatagaa agaattaggc ttagttctgt
    80821 tgaaccaatt ttatttacag atgaatttgt aaatgaagtt ttaaagatgg ataaagtttg
    80881 tcctcattac catttatcac ttcaaagtgg atgtgatgaa actctaaaaa gaatgaatag
    80941 acgatacaca actttagagt acaaaactat tgtagataga ttgagaagta aaatgccaga
    81001 tgtggcaata actacagatg taatagtagg ttttcctgga gagacaaatg aagagtttaa
    81061 aaaaacgtac gagtttttaa aagaaataga gctttcacaa atgcatattt ttaaatattc
    81121 accaagaaaa ggaactccag ctgcaactat ggaaaatcaa gttgaccctc aaatgaaaca
    81181 ctttagaagt gaacaacttt taaatttaag taaagtaaat tttaataaat ttgcaactaa
    81241 atttatcggc cgtgagttgg atgttttgtt tgaacaaaat atagaaggca ataaatatga
    81301 gggattaact tcaaattata taagagttgt tgttgaaagt gacaaaaata tacaaggtca
    81361 gatattaaaa gtgaaaataa atgatgtaaa agatgaatat gtggaaggaa ttttgctata
    81421 acatgtagaa attataatat ttataagata ggaggtggaa agaatggatt gtattttttg
    81481 taaaatagcg aacggagaaa taccttcaac taaagtttat gaagatgata gagtcttagc
    81541 ttttaatgac ttgaacccag ttgctccata tcatatatta gttgtaccta aaaaacatta
    81601 tgatagttta attgatattc ctgataaaga gatggacatt gtgtcacata ttcatgttgt
    81661 tattaataaa atagctaaag agaaaggttt tgaccaaact ggattcagag tcataaataa
    81721 ttgtggaagt gatggagggc aagaagttaa acatttgcac tatcatattt tagctggtaa
    81781 aaagcttcct aattacgaag caggacaaaa ctaaactaaa ttattgaaaa attgagttcc
    81841 ttcttgataa aaatacttga taaaagtaaa aatttagttt ataataaaca aagtgttagg
    81901 ttgtaatgca tattatgcaa aaagaacata gttacagtcc cagcataatt gcgctattgg
    81961 agggagggaa aaagaaatgt cagaagtaag agttagagag aatgaaacat tagacagcgc
    82021 tttaagaaga ttcaagcgtc aatgtgcaat gtctggcatc atgtcagaag tgagaaaaag
    82081 agagcactat gataagccaa gcgttaagcg taagaaaaaa gctgaagcag caagaagaaa
    82141 aaacgctaag aaatagtagt aaataagaat aaagaggtga aggggatgtc ccttaagcaa
    82201 aagttacaag aggatttgaa atcttcgatg aaaaacaaag atacagtgag aaaatctgta
    82261 gtaactttaa taagagcttc tataaagcag tatgaggttg ataatagggt cgagcttgat
    82321 gaagatggaa ttatcgatgt aatagcaaaa caattaaagc aacgtagaga tgcattagtt
    82381 gaatttgaaa aagctggaag agaagactta ataaaagaaa cagaaggtga aattgaagtt
    82441 ttaaaagagt acctacctca acaattaagc gaagaagagt tagaagaaat tgtaaaatct
    82501 actatatccg aagtaggggc aacttctatg aaggatatgg gaaaaataat gtcagttatc
    82561 caaccaaaag ttaaaggaag agctgacgga aaacttataa ataagttggt aaaacaaaac
    82621 ttacaataga ttgatatagc ctagagagaa atctctaggc tttttatagt ttttgggaat
    82681 aacgagtcat atttgagcat atctataatc aaagaaaatt ttgaaagaag gggaaaaatt
    82741 tgattatatc agtaaaagag attaggaatt ttttgataaa catatttata ccactaataa
    82801 taggttactt aagtagcatc ttaacaatga ttatcagtgg aacagatatt tcaacctatt
    82861 atttacaact cacaaagcca agctttgcac caccagcttt tatctttcct atagtttgga
    82921 ctatattgta catattgatg ggtatatctt catacctaat attaagaaag ggttacaact
    82981 tacctaaagt aagagatgca attttttatt atggattaca acttgtatta aactttattt
    83041 ggagtatact attttttgga tttggactta gatttacagc tttgatagat ataataataa
    83101 tgattttggt ttctataata atgatttcga agttttctaa aatagataag agatctggat
    83161 acataaattt gatttattta atgtggcttg tttatgcagg atttttgaac tattttatat
    83221 ggtttattaa taaatagaat gtaaagattt tgtaaattac cctgtacttt taataatatc
    83281 ataacaaacg aaaaataaat agactattaa aaataatcat tttcatatac aataatatta
    83341 atttaaatac aataaattta taaaaattgt atttaaagat taacatatta aagtattaga
    83401 attggaaagg cttgaaggga gaggttttta tgcaaataat agtatctgga agacaaatga
    83461 aattaactga cggaataaaa ggatacgtag atggaaaatt aagtaggtta gaaaaatacc
    83521 ttgatcctga atcagaagtg aaagtaacag taagtgcgaa aaaggataga caaaaagtgg
    83581 aggttacaat aattcctatt aacggtcaaa taataagagc agaagacgta gaagatgact
    83641 tatatgcagc aattgatatt gtttgtgaca aattaagtag acaagttgtc aaatataaaa
    83701 ctaaagttaa agacaaagtt caaaataata agagcataag atttgaaaat cttgacttta
    83761 tagataatag cagtgaattt gatgattatg attatgatga tgaagaagat gaaaatatag
    83821 taatagaaag aagaaagaaa tttaatgtaa aacctatgag ttctgaggag gcgatacttc
    83881 aaatggaact agtaggacac aatttctata tgtttagaaa ccaagataat tttgaaataa
    83941 acatagtgta taagcgtaaa gctggtggat atggtttaat agaacaagat taataaaaat
    84001 tgtatacgtt tagattttat ataagaaaaa ataaaaaggt aatcatgttg attttttatc
    84061 aatatgatta cctttttctt gtttaaataa tatattagat attaggtatt tattatataa
    84121 aaattttaaa actaatctgt tacaacatca ataaagtgca taaataccta tttcaagcat
    84181 aaaattaatt aagggggtaa tgcttatgtt agaaatatcc actgatttac aagtaaatca
    84241 accagttatt actgttacaa gtaatacgtt tattagtata gaaaattatc tatcaatatt
    84301 agaatatgaa gttgatttaa taagaataaa gactaaagtt aaaacaatta aaatatctgg
    84361 ggataaactt tcacttaagt atattactga tagtgagata ggtataaaag ggattatcta
    84421 caatgttgag tatgttgatt aggaggagat acacttgata agttttataa ggggatacta
    84481 tgttatagtt gtggaaggag taggactcga acaattttta aatcatctta taagaaatgg
    84541 gataagtgtt tacaatgtaa ctagaataaa aaatactaaa atggagtttc atatagatag
    84601 acaagatata aaagaattta agaatgttta tagaggaagt aagtttgata taaaggtaaa
    84661 acaaaaaact ggggtccctt ttattatcaa aagagtttat aagcacaaag gtatgtggat
    84721 ttgtgctctt gtttctttat ttttattgat gtctacatca cagtttgtga cagatgtata
    84781 tatacaatcg cctgaaggta taaaaaaaga agctcttaga aatgagcttt ataaggttgg
    84841 agtaagacca ggagtctata agaagagtat tgatagaaaa gaagttagag accatatgat
    84901 gtcaaaattt aatgatgtgg catatttatc tatcaatgta aaaggaacaa atatatttgt
    84961 tactgttaca aaaaaggcag aatccctaaa atctacagac caatcaaatt attgtaatgt
    85021 aattgcttta aaaaatggta taatagaaaa ggtaatccct agaagtggta aatcagttat
    85081 taaatctgga gacatagtcc aaaagggaga tgtcttatta aatggagcta ataccaagtc
    85141 aataccagaa gtatgggcaa gtacttttta tgagtccaca aaaaaggcaa gttatgtaga
    85201 tactgtaaat aaaaaaactg gagaaaagaa aaatatatat acactaagtt tttatgataa
    85261 agagtttaca atgagaaaaa atataaaata taaagattat gttgttgaaa ataaagaaaa
    85321 aaaactatca ataggaaact atacttttcc aataaagata aaaacgagta ctttttatga
    85381 aacaaaaaag gttgaagtaa aaaggaataa agaagagtta aaaaaagaat tatctgaaaa
    85441 agctttaaaa gagttagaat acataatccc agcttcggct agaataatag atgtaaaaca
    85501 taactttaag gttaataaaa atatgttaga atatttaata acagttcaaa ctagtgaaaa
    85561 tattgctaaa atttatcctc ttagtaagtc agaagcagaa aggtttataa aggaagaaag
    85621 taaaccagat gaaggtgaag aggaagttcc ttccaatcca gaaaaaagac cattaaatga
    85681 tataagaaat gagtttgatg aggataataa ggataataaa gaccaaaaca attctgatga
    85741 aaataatagt aatcaaaata gtaataatag tcaaaataat aatagcaata acaactaata
    85801 aaattaaact taaaatctta ggaggactaa ttcaattgat aatacaaaag aaatttacaa
    85861 tagcagatgg taactttgaa agagagttat ttggcaactt tgatgaaaat gtaaaattaa
    85921 tagagaagac tttaaatata gatgtaatac ttagagaagg caatataatt ttaattggag
    85981 aagaaaaaaa tgtagattct gcattaaaac ttatgaatga attacaccaa actgtatcaa
    86041 atggtaagca tttagataag cagagtattt cttattcatt atctcttttg cttgaaggaa
    86101 gtgaacaaaa aataaaagaa cttgagggga caatcgtcat aactcaaagg ggaaaaactg
    86161 ttcaacctaa aactttaggt caaaaagaat atataaaact tatagaaaat aatgatataa
    86221 cttttggtgt tggacctgct ggaacaggaa agacttatct tgcggttgct atggcagtaa
    86281 aagcttttaa aagagatgaa gttagtagaa ttatacttac aagaccagct gtggaagcag
    86341 gagagagtct aggtttttta ccaggagatt taaaggacaa agttgaccca tatttaagac
    86401 cactatatga tgccttattt gaaatgttgg gtgctgataa atttaataag tatttagaaa
    86461 gaggtactat tgaggttgca ccacttgcat ttatgagagg tagaacactt gataattcat
    86521 ttataatatt ggatgaagct caaaatacta cttctgaaca aatgaaaatg tttttaacta
    86581 gacttggatt tggctctaaa gctgtagtta caggagatgt aactcaaaca gatttaccac
    86641 aaaataagaa gagtggtcta atacaagcta cagagattct taaaggtgtt ccaggtattg
    86701 ggtctataat gctaacagat agagatgttg taagacatga gttggtacag agaataataa
    86761 gagcttatga gaagcacgac aaaagagaag aatttaaaaa agaagaacgt aaaaaagcga
    86821 aaatgcagga aaagactttc aaaagaaagt aaaagtgtag taatatatat atatagcatt
    86881 attaatgaat aaaaagtagg tgtagtgaat ggatttgata ctagatgata gacaagataa
    86941 attagaagta agtgaggagt taattgaaaa gataaaggat ataatcatag aatgtttaga
    87001 ttatgaagga tatgatgata attatgaagt gagtctttct tttgtagata ataaagagat
    87061 tcatgaatta aatagagaat atagaggagt tgatagagtg actgatgttt tatcatttcc
    87121 tcttttaagt gatgattttg aggatgttga gttagaagaa gaatccctag gtgacatagt
    87181 agtatctctt gaaagagcct tagaacagag tatagagtat aaccatagtt ttgaaagaga
    87241 agtatgtttt ttaatatgtc atagtatgtt tcatctttta ggttatgacc acgatacaga
    87301 tgaaaataca aaagaaatga gagaaaaaga agaacacata ttaaataagt taaacataac
    87361 aagggagtag tttttatgaa accagaaaaa actcgtcaag gtataattaa agcatttaat
    87421 gcagctatag aagggatatt gtatacattt aaatttgaaa gaaatatgaa aatacattat
    87481 ttaggttcag ttgctgttct tataataagt ttgtttttta acttttcaaa attagaaatg
    87541 ataatgttac ttatgtccat atgtttagtt gtagttgctg aaatgtttaa tacagctata
    87601 gaaaaagctg ttgatttagt aactgatgaa tatcatgttc ttgctaagat agcaaaagat
    87661 gttgcagctg gaggcgttct agtggcagca ctaaattcag tagtagttgg atatattttg
    87721 ttttatgata aattgacaga tatatctgga atattaattt ataaaataag agaatcagaa
    87781 ttacatataa ccttgatatg tatattattg gttcttatag ctgttgtagt tgtaaaagca
    87841 ttgacttcta caggtactcc tctaaaagga ggaatgccaa gtggtcatgc tgccttagca
    87901 tttgctatag caactgcaat tacacttatg actgaaagag ttgttgcctc tactcttgca
    87961 tatataatgg ctgtattagt tgcccaaagt agaattgaag gaaaaataca taccttttgg
    88021 gagactattg ctggagcttt attaggtgtg ttgatagcta tattagtatt tcagcttgga
    88081 atgttctata attaaaataa atgtacataa aatatttaaa ataaaacaaa tctgtgctaa
    88141 ttaaattttt atgatataat gtagagtatt aaataaaaat aacttttaat tattgtatac
    88201 aggaggagtt gttgtggata acatagaatt gttaaggttg gcagaagatg ccagacaaca
    88261 ttcttatgct ccttactcag gttttagagt aggtgcagct cttttaacta agagtggtaa
    88321 agtttatact ggatgtaata tagaatgtgc atcattaggt ggaacaaatt gtgcagaaag
    88381 aacagctatt tttaaagcaa tatcagaggg tgataaggat atctataaaa tagctatagc
    88441 aagtgataac tcagaaaata atgagcaaac atatccatgt ggaatatgca ggcaggtaat
    88501 tatagagttt ggttctgata taaaaataat aacgggatat actaaaggag aggtgtttga
    88561 gcatagtata aaggatttgt tgccaaacta tttctctgga aatgatttaa aataaattta
    88621 aaagtataaa taaatttaag taattaaaac aagaagataa aaagttagga gacagttaat
    88681 gttcaaatca ggttttgtca gtatagtggg tagaccaaat gtaggaaaat ctactttaat
    88741 gaataatgta gttggagaaa aaatagctat aatgagtgat aaacctcaaa ctacaagaaa
    88801 tacaatacaa gcagtatata cagatgaaga aatgcagata gtattcttag atacaccagg
    88861 tattcacaaa ccaaaaaata aattaggtga atttatggta aaggcagcaa cagaagcttt
    88921 taaaaatgta gatttaatat tatttgtagt tgatgattct aaaaaaatag gtcctggaga
    88981 tagaaagata atagaagatt taagaagtgt taagacacca ataattttag ttgtaaacaa
    89041 aatagaccaa ctagaccaaa aagatgagct atttgatata atcaaaatgt atgatagaga
    89101 aggtattttt aaagaaatag taccaatatc agcattaaaa ggaaagaata cggatacctt
    89161 aataaaagtt atacaaaatt atttagaaga agggccaaag tattttccag attatatgat
    89221 tacagaccag ccagaaagag tattaatagc agaacttata agagaaaaag ttcttcacta
    89281 tcttaatgat gaaatacctc atggtgtagc tgttgaaatt gaaaaaatga aagcgagaaa
    89341 tgataaggaa atagtagatg tatctgctgt aatatactgt gaaagagatt cacataaggg
    89401 aataataata ggaaaaaatg gtaggaaact aaaaggaata ggtaagtcag caagacaaga
    89461 tatagaattg cttttaggtt cacaaataaa tcttcaatta tgggttaaag tcaaagaaaa
    89521 ttggagaaat ttacaaaatt atataaataa ttttggatat aatgataaat aaaggtgggt
    89581 tatatggata ggaaactgga tgcttcccaa gatttattat atgaagtaaa atcattaatt
    89641 gataataata aagtattgga gttaagagaa ttaatagagg aatatcatat aattgatata
    89701 ttcgatataa tggaaaattt agaggaagac atgaaaattc aattatttga agtacttcct
    89761 ttagatatgg catcttctat attagaagaa ggtagtgtag agttttttat tagtatttta
    89821 tctaaactgg atgtagaaca ctcgaaaaat atacttgaac ttatgtctct tggagatatg
    89881 gcagacaagt tgagtgaact tgaagaagaa gaaagagaac acataataaa tcttttgaat
    89941 caagagaatg ccgattatgt aaaagagtta ctattctatg atgaagattc tgctggtgga
    90001 acaatgacca ctggatatat ttctataaat aaagatatga cagctcttga ggctatagac
    90061 catatgagag aagaagctga agaagctgaa actatttatt atatatatgt ggttgatgat
    90121 gaagaaaaac tagttggagt attgtcatta agagaattaa taatagctag agacgcaaat
    90181 atagtagaag atttgatgag tgaaaatata atctctgttt atgtagatga agatagagaa
    90241 gaagcagtaa gattagtatc taaatacaat ttaatagcaa ttccagtagt agacagacaa
    90301 gaaaaattaa aaggaataat aacagtagat gatataattg atgtaatgga agaagaagca
    90361 actgaagata tgtataaatt tgcaggaagt tcagaacatg aaagagaagt tgctgaaaaa
    90421 gaaaacccta cattgagaga gcaaataata tcagcactta gaggacgatt accttggtta
    90481 attattacct tagttggagg gttgttggct tcgttaatac tttctaactt agactatata
    90541 atgaatcctg tatatgctcc attagtattt tttatacctg tagtaattgg tatgggtgga
    90601 aatattggaa ctcaatcatc atctgttaca gtaataacat tatctaataa ggatttaaat
    90661 tttagcaatg tggttagaga aggtattgta ggtattatta caggtctttt gtgtagtata
    90721 ataacaggta ttgtaattta ctttgttatg agaaagttag acattgtatt aattgtttca
    90781 atatcattat ttataaatat ggttttaggt gcaacaatag gtgcgtttat gcctgtttta
    90841 ttaaaaaaaa tggatgcaga cccatctaca gtttcatcac caattatatc tacagctctt
    90901 gatataactg gtatagcagt ttactttata ataacaacgg cattattgtc aaaaattgtt
    90961 taataacttt atgtatgatt tatcctcttc ttactaaaaa tataagtata aatgtaagaa
    91021 gggggttttt taaaaatgaa caatatcagt tgggaagttt ttaaaaaaac aggtagtata
    91081 gatgcatatt tatatttctg tgattgcaaa aacatacatg aagaaattga agaagtaagg
    91141 gagaaaaaag aagacgatga taatcctgaa cacccagggg atagtactta aagctataag
    91201 gtataaggaa agtgacataa tacttacact atttacaaga aagcttggaa aagtatctgc
    91261 aatagcaaaa ggagctaaaa aaaataagag ctctttgctt tcatcatcac agttattttc
    91321 ttatagcaat tttaccttaa aaaaacaagg taatatgtac aaggttactc aaagtgaaat
    91381 aataaaaagt ttttataata tatcctatga tatagaggca ttttcttatg ctacatatat
    91441 tacaaaatta gttgaaaatt ctatacttga aaatcagact aataataggc tatttatatt
    91501 acttgcgcag actctgtatt tgtatacaca ggataataca gacaataggt ttataacagc
    91561 agcattcgag ttaaaatttt tagactatat aggatttaaa cctatagtaa ataaatgcat
    91621 taattgtgaa tgtaaaattt tacaaaattc tgtgtttaat atctacgaag gtggtatact
    91681 atgtagtaag tgtagtaaac tttttgataa taatataaaa ttagacttaa caactataag
    91741 tcttatggaa tatgtattaa gaaatgatat tttaacatgt agtaaagcta aagtatcaaa
    91801 atatataaca catgaacttg agaatattct agacaagtat ttgaaagttt atgttgataa
    91861 tattaatttt aaatcattac acgtattgca aagtgtaaaa aataataagg gagtggataa
    91921 tgatgagtag taatataact attgaaatgg ttgattcagt ctttgaaaga gttccaggag
    91981 caacttatgc agaagcaaaa gaagcattag taatgtgcaa tggagatgta attgaggcag
    92041 taatatattt agaaaataaa aaaaatactt gtaattgtaa agcaaaatct gctaaagaaa
    92101 ctatggaaga agtatttggc aaagatggag aaaatataaa gtttcaatta aaagagcttc
    92161 ttagaaaaag tagtgtagtg agaataatag ttgaaaaaga tggaaaaact atgatgaaca
    92221 ttcctttaac agttggagtt gttggattag cttttgtacc attagctact ttagttggat
    92281 tatcagctgc tgttataagt aaatatcgta taaaagttca aaatgaagaa gatggagaaa
    92341 ttgtagattt aggtgaattg aatgaagaaa aacttcacgt tttgaagaat atgataacta
    92401 atgcagcaaa agatgtgaag gatgtagtag ttgacaaaaa agaagatgac aaagatgtaa
    92461 ctgctgacct tatgaaagaa gaatctgaaa agaataaaga agacgaagac gaaaataaat
    92521 agatataaag tgacttttaa aaaatgaaga gaagataatt ataagaatta tcactaacat
    92581 tgacaaattt tatagaattt gatattctaa aagttgtaga agaactatta aaatagcctt
    92641 tcgtgtagac gagaggcttt attgttatag gagggatttt tatgaatttt caagagatga
    92701 tactggcgtt gcaaaaatac tggtcaaagc aaggttgtat catgatgcag ccttatgata
    92761 ttgaaaaagg tgcaggaact atgaatccta atactttttt aagatcatta ggacctgagc
    92821 cttggcaagt atgctatgta gagccttcaa gaagaccagc agatggaaga tatggtgaaa
    92881 acccaaacag actatatcaa catcatcaat tccaagttat actaaaacct tctccagata
    92941 atatacaaga attatatttg gaaagtttaa aagagattgg aattgaccca agtgagcatg
    93001 acataagatt tgttgaagat aactgggaag ctgctacagt tggtgcttgg ggacttggat
    93061 gggaagtttg gctagatggt atggaaataa ctcaatttac gtattttcaa caagtaggta
    93121 atattgaatg tgagcttgag acaggagaaa ttacatatgg attagaaaga ttagctatgt
    93181 acattcaaga agttgatagt gtttatgatt taaaatggaa tgataaaata acttatggtg
    93241 aagtatttaa taaagctgag tatgaaaact caatgtacgc atttgaatta tgtgatgcag
    93301 atatgttgtt taatctgttt gatatatatg aaaaagaagc attaagactt atggaaaatg
    93361 gacttgtaat accttcatat gactatgtgt taaaatgctc tcatgcattt aatacattgg
    93421 atgcaagagg tgcaatagga gttagtcaaa gagcttcatt tataggtaga gttagaaata
    93481 tggcaaagac tgttgcagaa acttttgtaa aacaaagaga agaaatggga ttccctcttt
    93541 taaaggacgg tgacaaataa tgaaaaatta tcttttattt gaaatcggtg ttgaagaaat
    93601 gccatcaaga tttgtaggca gtacactaga acaattaaaa aacaatctta gtaaattatt
    93661 tgatgaaaat agaatagctt ttgataaaat aaatgcgtat gggacaccaa gaagacttac
    93721 tttagtagtc gaaggattga gtgatagaca aaatgattta gaagaggaaa taaagggtcc
    93781 tgctaagaaa attgctgttg atgcagaaaa taatttaaca aaaccagcat taggatttat
    93841 aaaaagcaaa ggattaagcg aatctgacat atattttaaa caagttggaa aagaagaata
    93901 tatatttgcg actataaagc aagatggaaa agaaacttca gaagtactaa aagacatatt
    93961 accagagact ataaaatctg tagtattccc aaaagctatg cgttggggag gaaaaaatct
    94021 taaatttgca agacctataa gatggatagt tgcattgtta aatgataaag tattagagtt
    94081 tgatttagaa ggaataatat cttctaatgt aacaaaaggt catagatttt taggtgaaag
    94141 tacaatagaa gttgattcta tagaagatta ttttgaaaaa ttagagaaaa attatatagt
    94201 tttagaccaa aacaagagaa aagaaatgat aagaaaacaa tgtatagaag tggcaaattc
    94261 tttaggtgga gaagttgaat ttgatgaaga tttacttgaa gaggtaactt acttagttga
    94321 atatccaact gctttttatg gagaatttga tgtggattat ataagactac caaaagaagt
    94381 tgttataact cctatgaaac aacatcaaag atattttcca gtacttaaag aaggaaaact
    94441 gttacctaac tttatagctg ttagaaatgg tgattcttac agaatagaca atgttaaagc
    94501 tggaaatgaa aaagttttag aagcaagact tgcagatgct ttatttttct atagagaaga
    94561 tactaagaga aacttagaaa gctacataga aaaattaaaa actgttgtat tccaagtaaa
    94621 actaggaact atttacgaca aaactttaag acttgaaaaa ttaagtgctg atatacttga
    94681 tagtttaggt ttagtagatg aaaaggcaga tactataagg gctgctaaat tatctaaggc
    94741 agatttagtt actggaatgg taggagaatt tgatgaatta caaggtttta tgggaaaaga
    94801 atacgcaaaa gttggaggag agaatgatct tgtaagtgaa gctatttttg aacattatct
    94861 tccaagattt gcaggagata tacttcctaa gactaatgca ggagttgcct tatcaatagc
    94921 tgataagttg gattcaatag caggtttctt tgctatagga atacaaccaa caggttctca
    94981 agacccatat gctttaagaa gacaagcttt aggtatactt agtatactta tggacagaaa
    95041 agttgctgtg gatataaaag tacttattga acatgcttta gacaattatt ctgaattaga
    95101 ttttgataaa gaagaagttg ttgagcaaat aatgaatttc ttcaatgaga gagtaaaaaa
    95161 tctatttaaa gatttaggaa taagatatga tgttgttgat gctgttttaa gttctgatat
    95221 aaatgatgtt tctgatatgc atatgagagc tttagagctt aataattggc tagaaaaaga
    95281 tgaattagtg gagatgctta ctgcatttaa tagagtttct actctagctc aaaaagcaga
    95341 aagtgataaa attgatgaat ctttattaaa agaagatgct gaaattaaac tttacaatga
    95401 atttaaacaa gtaaagataa aagttaatga attattaaag gataagaaat atggtattgc
    95461 tttagatgaa tttgcatctt taagaccagt agttgataat ttatttgata cagttatggt
    95521 tatggataat gatgaagcta ttaagaacaa tagacttgct ttacttaaac aagtatacga
    95581 tactatgcta gaaatttgtg atttatctaa aattgtttat aaataaaatt taaactcttt
    95641 ataagaaata aggctgtctc aaaatagaga tagtcttatt tttcattgtt gagatgatga
    95701 aaatatattt gatttcatag aaaaagagtg tctcataaac taaaaagttc attttgagac
    95761 acccatgttt tttgtaagta aatataataa attatatttt atacttatca gttattttgt
    95821 ttaaaatatt atcatttgaa tttacccatt cataaaaatt gcctgatgat gcgtccgata
    95881 ttttataaag catttcagga atatcactag ctttaaaatc tccaagtgat tttcccaatc
    95941 tagtcttacc tatttcaaaa ctgcctccaa caaataattc aaatgcatct gtagatatac
    96001 catcaacatt cttcttttta ccacataaac ctatgctacc aacttgatga acaccacatg
    96061 aatttaaaca tcctgatata tataacttag gtgctttatt taaaatttct tcattatttt
    96121 gtaatctaaa ataatctatg atttcatgta acattttctg actattttgt atgcccattt
    96181 gacaaattgg aacacctatg caagatatac tttgttctaa ttgagaatta caactaatag
    96241 ttttacttat ttctaatatt ctttttgctt catttccatt taaatttaaa atatataatc
    96301 cctctgtcat tcctagtcta atcataggat tttcaacatt atctaattct ttaagtaaag
    96361 tacttaaatc ctttgttaac aaaatacctc caactggatg tatatataca gtgtataaac
    96421 catcctgttt ttgaggtatt agtctagaat cctgtatatc tattttaact ccaggtttag
    96481 agtaatctat ttcttcaata ttgagttcaa gactaccatt ttctttttct aatttatagt
    96541 attctttaaa tttttctaag aatagttctt caccaagtga ttcgaccata tatctaaccc
    96601 tagctctgtt tttattttca taatttccat aatccataaa gaatttaatc ataccttcaa
    96661 cacaatataa ggcatctttc ggctttataa gttcatcaag ttctaaagca actttgggtt
    96721 gtttacctag acctccacct aagaaaactc tgaaatatgg ttcatcattt ttcaaagtag
    96781 caacaaatcc taagtcttgt atactacaat gagcagtatc tgtgtaacaa ttagaataag
    96841 aaacttttaa ttttctaggt aaatggtatg tagtagcatt tttgataaaa tatttatcag
    96901 tagcaactgc atatggagta acatcaaaga cttcactagg gtcaactcca gataatggag
    96961 ataatccgac atttctagga taattaccac caccacctct agtgaatata tcatttttta
    97021 ttccttcttc catgatatca acaattgaat ttatagataa atcgtgtaat tgtatagctt
    97081 gtctagttgt taagtgtatc ttatctaagt tgtgtttaat agctatttca tagattttat
    97141 taagttgata ctgagataaa acaccagcag atactctaag tcttatcata aaagattttt
    97201 tgtctctttg agcataaaca ccatatccac cagaaaatcc cttatattgc attttattta
    97261 tttctccatt taaaaatttt gaagaatatt ctttaaaatt aggtagttca tttaacaata
    97321 tctttttaaa attatccatt atttcacctc attgttagtc ttgtataaaa atatatctat
    97381 tgtataatag atatatatat tattatctag tcaggataaa aatataacag aataattcta
    97441 ttaaaagtaa gaataataag gacatagtga gtattttgtt tttattttac aaattaagta
    97501 taatattttt gttttataaa atataattaa gataaataga taattttgta attttaatat
    97561 ataatattta gtagagtgtg ggagtagcac ttaatatttg caggaggagt ttttgtatat
    97621 gggagaaata ataaatgcat tagatagagc cctagacata attttgctgt tatatcatga
    97681 aaagagagaa atgggaataa ctgaaataag caaggctatg ggagtatata aaagtactgt
    97741 acatagaact ttggttactc ttgaaaacaa aggttttgtt atacaaaatg cagagaatgg
    97801 taagtattgg ctaggaataa atttatatgc aataggtatg gttgtgggag aaaaaatgtc
    97861 attgactgaa atagtaaaac catatacgaa aaaattaaat caagaattta acgaagtagt
    97921 taatgtatct atattagaag aaagagctca agattctcca agaagtatca taatacataa
    97981 agagtatggt tcaaatcaat tactttcagt aaatccatcc gttggttcaa gtagtgaatg
    98041 ttattgttca gcagttggta aatgtcttat ggcatttaat gattctatag attttgaaaa
    98101 atatagaaaa acaccaatac acaagtatac agaacatacg attgataatt gggatgatat
    98161 gatgcttttt ttagcaaaaa taaaagaaca aggatatgct atagatgatg aagaactaga
    98221 acatggacta acttgtattg gagcacctat cttagataaa aataataaag ctattgcagc
    98281 cataagtttg tcaggtccaa ctataagaat gagagaaggg gactttgagt ataagattaa
    98341 aagagttata gaaactgcaa aaagtatatc tgaacttttt agatgatttt taatctcgat
    98401 aataaaaata ggctatattt aaattgttat ttgtaaatat caatttaaat gtagcctatt
    98461 tttctttaat ctaaaattaa atattcttaa aatttaaaat gttattgaaa tatataagcg
    98521 aatgtgttat cttttaatta agcaataaaa atagaacaag gttctatact atagaacaaa
    98581 attgatgcat atatagtatt tatacaaaat ataaatatta tatatttaaa attaagtaaa
    98641 aatattacat aaaggggaga tttgagaaat ggaaaaagtc aagttgagtg ttgaaagatg
    98701 taagggatgc tatctttgta ttgaagcttg taaaaaagat gcaataagtc tttctgacta
    98761 cacaaataaa aaaggctttg taactattaa agtcgatgaa gaaaaatgta ttcaatgtgg
    98821 cgcttgttat acaatgtgcc ctgatttagt atttgagata ttataaatta tttttattag
    98881 aggggagaaa aggtatgcaa agtttattaa ttaaaggaaa tgaagcttta gcagaaggtg
    98941 ctatacgtgg tggctgcaga ttttatgcag gttatccaat aacaccacaa tcagaaatat
    99001 tagaaatgat ggcatggaga caaaaagaag ttggaggagt atttatccaa ggtgaatcag
    99061 aaatagccag tgtaaatatg gttatgggag caagtgcact tggagcaaga gctatgactt
    99121 cttcatctgg tccaggattt tcattaaaac aagaaggtat tgcatattgg gtatcagctg
    99181 gtttgccagc agttgtagca tgtgtgcaaa gatatggtat aggtgatgga tttataggag
    99241 ctggtcaaga taattattgg caagcagtaa aaggcggtgg aaatggagat tatcatttaa
    99301 tcgtgttagc acctaatagt gttcaagaaa atatggatat ggcatatgaa tcttttgaat
    99361 tggctgaaaa atatatgcat ccagtactta tactttctga tgctacaata ggtcaaatgg
    99421 tagaaccttg tatagcacca ccaatgaaag aatacgatat ggataaagct ccatgggctg
    99481 caaaaggaac acctgtagga gaaaaaaata aagtaataac tgatataaca tattttgaag
    99541 accaagatac atggcaaaaa gggtatatag aaaaaatgag aaaagttcaa gaagatgaac
    99601 aaagatggga agagatagaa atagaagatg ctgaagtggt atttgtggca tacggtattt
    99661 catcaagaat agcagaaggt gcagttagag atgctagagc aaaaggaatg aaattaggtc
    99721 taataagacc aaaaacattg tggccttacc caagaaaagc atttaagaaa ttaagtgatt
    99781 cattgaaggg acttgtaaca gttgaaatga acatgatggc acagatgaag gaagatgtaa
    99841 ttatagcatg tgataataga tttccagtat attcagtagc aacagctcaa tatatggcag
    99901 aagtaaatca attaatagat tttgctcaac agattataga tggaaaagct aagcaagagg
    99961 aggtatttta attatggcta aaaaagcacc agcaataatg atgtgtgaaa atatgttctg
   100021 tggaggctgt ggacactcta tagtcgatag aattattgga gaagtattaa cagaaatgga
   100081 tatatgtcaa gatacaatta tatgttcaga tataggttgt aatcatatgt ttcaatttag
   100141 tatgaatgta gatgttgtcg ttccacctca tggtaaaatg ggagcagcaa tggcagctat
   100201 gaaaagagtt agaccagata aatatatatt tacaatagct ggagatggtg gggcttatgc
   100261 aatagggctt ggagaaacta tgtcagctgc tactagaaat gataatgtaa tatttcttgt
   100321 tatgaacaat aatatgtttg caatgacagg agggcaaatg gctccaacta ctatagaagg
   100381 tcaatataca gcttctactc cagcgggtag aaattacgca gatcatggtt caacatttga
   100441 tgttgtaaaa gttatgggaa atttagatat agcatatcta gcaagaggaa caataactaa
   100501 ccctaaagaa ataaatacaa caaaaagata catcaaaaaa gctctagaaa aacaaaaaga
   100561 aaagaaaggt ttttgcttaa tagaagtgct tgtaccatgt ccaacaaact ggggattaaa
   100621 gccagtagat gctatgaaga gaattgaaaa tgaacttgtt ccaaagtatc cacttggaga
   100681 atttattgat tagggaggaa ataatatgtt gaatgaaatt atatgtgctg gttttggagg
   100741 acagggagtt cttacagcag gaaaaattat aatgtatgtt gcatataagg cagaaaagaa
   100801 aattacatgg ttcccatctt atggaaatga gatgagggga ggaagtgcaa attgcaatgt
   100861 tgttgtaagt gatgaaaaaa ttgcaaatcc ttgtgtaaaa aatccagata tactattggg
   100921 aatgaacagc gtatcagtag ataagtatga aagtttaatg aaaaaaaatg gttatatgtt
   100981 tgtcaatgaa tcactagtaa gtaaggatag aaagtacaga gaagacatta atgttataaa
   101041 agtacctgtt actgaaatag cacaaaattt aggcaatgaa aaagctgcta acatttgcat
   101101 gttaggtgct atggtaaaga gtttggattt atttacaaaa gaagaatttg aaagtggtat
   101161 gtgtgaatac tttgaaaatc aaggcaaagg taaattcaat tctaaaaatg tagaagcatt
   101221 tgaagctgga tacgactacg aatgaatatt ttaaatattt aaaataatta ttgaaatact
   101281 tatttttata tgttagtatt taattaataa aatatagaac gtcgttctga acaataggac
   101341 gaaattttta ggtcggaata caagaacggc gttctgcata gtagaactag ggggtgttaa
   101401 attgaaagtt ttagtaataa atcctggtgg tacatccaca aaaatttctg ttttccaaga
   101461 tgaaaatgaa attttgaaaa aaaatataac ccatacaaga gaagatttaa aaaatttttc
   101521 taaagtattt gatgaatatg attatagaaa acaactgata gtagatattt taagtagtga
   101581 gaatcatagt ataaattctt ttgacgcagt agttggtcgt ggtggactta tgaaggctat
   101641 aaaaggtggt acctatactg tgagtgaaga aatgattgag gatatgagaa atgaaataaa
   101701 tggggaacat gcatcaaatt taggtgcatt attagctaaa actatagctg atgaaatagg
   101761 agtacaatca tttgtagtag acccagtttc tgtagatgaa tttgatgatg tatcgaggat
   101821 tacaggaata tcagacatag aaaaagcaag ttggttacat gcattaaacc ataaagctgt
   101881 ttcaagaaaa attgcacaaa aactaggggg aaaatacgag gattataact ttattgtagc
   101941 tcatttaggt tcaggaatat cgattgtagc acataaacaa ggcaaaatga ttgatggaag
   102001 tggtggtagg tctgatggtc cattttctcc agaaaggagt ggtggattac ttgcatatcc
   102061 tcttatagaa ttgtgttact ccggaaaata tactcatgat gaaatggtcg caaaagtaag
   102121 ttcgattggg ggaatgtacg attatttagg aacaaaggac atgatagaaa ttgaaaacag
   102181 aatcaaggag ggtgatgaaa aggcaaaact tataatggat gcatttattt atcaagtagc
   102241 aaaagaaatt tctatgtatg gagcttcact ttcagggaat gtagatagag ttatcttgac
   102301 aggagggata tctcactcag aaatggtagt caaaggagta gcagaaaaag tttcatatct
   102361 agctccaata gagatagtac caggggagat ggaaatggag gcacttgctc taggggcact
   102421 tagagtactt aatggagaag aaatagcaaa aacttattaa tatttaggag aaagagtatg
   102481 ttaaaagatt ttaataattt attagaagag gctaaaaagc ttgaacctgt tattgtaagt
   102541 gttgctgttg cagaagacaa agaagtatta aaggctgtga aatcagcaac agatttaaac
   102601 attataaagc caattcttgt aggagacaag gataaaatag aaagtatatc aagagaaatt
   102661 ggattaaaag gtcatgaaat aataggttgt caaaatcccg atgaatcagt taaaaaagct
   102721 gtagagatag ttaaaaataa ggaagctaaa gttcttatga agggattagt aaatacaagt
   102781 gtctatatga gagctatatt aaataaagaa acgggtctta gaacaggaag attattaagt
   102841 ttgcttgcag tatatgaatt acctcaatat cataaacttc tttattgtac tgatagtgga
   102901 ataaatgtat cgccaaactt aaatcaaaaa aaagatataa tgacaaatgc acttcttact
   102961 atgaaaagta taggcatgga aaatcctaaa actgcgatac ttactgcaaa tgaaatggta
   103021 gaccctaaga tacaatctac agtggatgcc aacctacttg tagagatgga aaaatcggga
   103081 gaaataccaa agtgtatagt ggaaggtcca atagcatttg atgtagcatt tgatgcacat
   103141 gcagcagaac ataaaggtat taaaagtaat attgctggtg atgttgattt attagtattt
   103201 ccaaatatag aagcagggaa tatattagga aagtcatggc ttagatttaa taaagctaag
   103261 tgggcaggta tagttttagg agcaacaaat ccgataattt taggttcacg ttctgacaca
   103321 gctgaaataa aaataaattc aatagcatta gcgtgcctag catcacaata agaaattatt
   103381 attaaggagg aaaaagtatt atgaaatatg caaaaagaat ggatatggta aaagcttcag
   103441 ctataagaga ttctcaaaag aaaatagctc agaaggtagc aagtggtgga actgttatat
   103501 cttttgctgc agggcttcct gacccaaatt tatttccaat agaagagata agtgaaataa
   103561 ctcaaaaagt acttaatgaa aggggaaaat ttgccctagc atatggacct actaaaggtg
   103621 aagatgagtt gttagatcta ttagtaaaaa gaatgaaaga agaagaaaat attgatacaa
   103681 aagcagaaaa tattataata actactgggt cacaacaagg gatagcatta agtgctatga
   103741 ttttattaga aaagggagat gtagtagtta cagaaaatcc aagttactta ggtgcaataa
   103801 atgcatttag accttatgaa tgtgattttt taggagtaga tacagatgaa gaaggaatgg
   103861 taacagatga tttagacaaa ttattatctg aaaattctaa cataaaggtg atatatgtaa
   103921 taccaacatt tcaaaaccct acaggaaaaa catggtcttt acaaagaaga aaagatttta
   103981 tggaagtcgt gaacaaatat gatgtcatag taatagagga taatccttat ggagaaataa
   104041 gatttacacc agaacctcta cctacactta aatctcttga tactaaagat aaagtattgt
   104101 accttgggtc attttcaaag gtattatgtc caggatttag agttgcttgg atgtgtggta
   104161 atgtagacat catagataag gcagaacttt taaaacaagg tatagattta cagtcaaatc
   104221 aattttcgca agtacaagta atagaatttt taaagaaata caacttaaat gaacatatag
   104281 aaaaaataag agcagagtat aagaaaagat gtctgctaat gttagatgct atgaagaaac
   104341 atttcccaga ggaagctaaa tatacagaac cagatggagg aatgtttata tgggttgaac
   104401 ttcctgaaag tataaatgta gatgatttat tggataaagc cattgatgct ggagttgctt
   104461 atgtttctgg agagtccttc tttgcaaata atggtccaaa aaatactatg agacttaact
   104521 atacaacaat gtcagaagaa caaatcgtta aaggtgttga gatacttgca gaagttataa
   104581 aaaaagaact caattatgct tgtgaataaa tataaaaagt gagggtttaa atatgggaga
   104641 aaaagaaaac ggtataaagt ttggaaagtt aatgtttcaa cttgttatta tagcaatatc
   104701 ttgggaatta gtttatatta taccatttat ccaatataca ttatatgatc caatcctaaa
   104761 agcattagaa tgtacaaaca ctcaactagg ttttctactt acaatttatg ggttaggtaa
   104821 tatatttgga gctcctatag gaggctggtt agcagataga tttgattata gaaagataat
   104881 tttaggttct gtatttctta atggagtagt atcattttta tttgcattta atatgaacta
   104941 tccatttgca gttgctactt gggtaggttg tgcaatcaca tcattagtta tgaactatcc
   105001 ttctatggta aaaatactta gagttatagg aaaagataat caaggtaagg tttatggatt
   105061 taatgaagct atggttggag tttctggagt agtaatggga gcaatattct tatatattta
   105121 tacatgcttt gcaactccta cattgggtat gagatgggta atgatatctt taggaatatt
   105181 atcaatagca atgtgtccag tattatggtt tgtaattaaa gatgtagata ttaaagaaga
   105241 aagagaagaa gcaggtgaaa aaatgtctgc tggtgatttt ataacagtac taaaatcacc
   105301 aaatacttgg ctagtgggaa taagtatatt ctgtgtatat tcattcacag ttacaatgtc
   105361 ttattttaca ccatatataa catctgtact tggaggttct gtagcattat ctggtgcatt
   105421 agcaataata agacagcatg gtctaaaatt atttggagca ccatttggag gatattgtgc
   105481 agacaaatta aaatctccta caaaagtgct tttaccaata tatgtatttg gtatagcagt
   105541 aatagtttta ttcctagtat tacctgcatc aactccaatg actatattca tagctttaac
   105601 atttgtagta ggtatattag gttacatggg aaaaggtata tattatgcag tacaagatga
   105661 agtaaaagtt ccagttaaat attcagcaac tactataggt atagctgcag ctttaggatt
   105721 ttcaccagat gtattccaat ttgcattaat aggacactgg atagatactt atggcaataa
   105781 aggttacaca tatacattta tattccaaat agcaattcta gttattggaa tactatcttg
   105841 tttatatata ttaaaggtta aaaagagaag agcaagtaaa ttagaagctt aaatattcaa
   105901 tttggtaatt aagtatatat aaatacaata cttattttga tgaatgtgat tgtataaata
   105961 acataaaaaa tatcaataga ttaagtttta taataatgtt tagagaataa agtataaaaa
   106021 tcaaaatgtt atcaagtttt ctaggtttta acataaagtt acccctgaag gtgtaaaatt
   106081 gagtggcaat tattatctat tttcttacct acataaacct atttaattta aattctaaga
   106141 gattttcaaa atagatggta gttgtactca attttaaacc tcataataaa tacgaaaatt
   106201 taaaatctaa ctagatacta tttaattata tattaataaa tatatattgt actatttata
   106261 taataataat ttcaggcttt tcattatatg tattccaatt tatattgttt gattattatt
   106321 caaacacacg tcgttaaaaa ttttataaat ttatgtttag atatgattaa tactcttgat
   106381 tttagaaata aatatttgta gattgtagat taaagataat ataaataaat agaaggtaga
   106441 ttttttagat atattaagat aaagattata taaaatattg aaatatagct gtttaaatta
   106501 ttgtctataa atataaaatg aatggtggtg agttaagtga ccgatttagt taacaccatt
   106561 aatggaattg tttggtcacc cgtattagtt gcaatgtgtt tgtgtatagg attatatttt
   106621 tcattgaaat taaaattttt tcaaataaga gatgtaaaag aaatgtttac tctcttgctt
   106681 gaaggagata gttctcatgt tggtatatca tcatttcaag gttttgctac atctatggct
   106741 ggaagaatag ggactggaaa tatagctggt gtagctgtag caatagcaat gggaggtcca
   106801 ggagcattag tatggatgtg cataatggct acattaggtt cagcaactgc atttgtagaa
   106861 tctactctag ctcaaatata taaagatgag catgatgggc agtatagagg aggacctcca
   106921 tattattttg aaaaaggtct tgggtggaaa aagtgttcag ttttattttc aatagttgca
   106981 ataataagtt atacattttt tatgcctggt acacaatcaa acactttata tctagcaatg
   107041 aatcaagcat ttggattttc aaaaatgaca atagcagtag catcttctat tgcattagcg
   107101 ataataattt ttggaggaat taaaaggatt ggtttatttg ctgaaaaagt agtacctata
   107161 atgggtggag cataccttat tatgacatta gtaataatta taacaaatat tagtttagtt
   107221 ccagaggcta ttgtaacaat gtttaaatct gcatttggat ttggttcagt ttttggagga
   107281 atgctaggtt cagcaatatc ttggggagta aaaagaggta tatactcaaa tgaagcagga
   107341 gaaggttctg ggacttatgg tgcggcagca gcagaagtaa gtcatccagc caaacaagga
   107401 ttagttcaag cattttctgt ttatgtagac acattattaa tatgtatggc tacaggtatt
   107461 atgattgtaa taacaggaat gtataatgtt acaggtgctt gcacagcact gccaggtgta
   107521 gaaccgggac cacaatatgt acagagtgca ataaacacat tacatccaca attaggtgat
   107581 atttttatag caatagtttt attattattt acatttacaa ctttattagc cttctcatat
   107641 atgatggaga ctaatgtatc ttacttagta actagaatta aagcagaaaa acatgaaaag
   107701 tacataatta atgtctgtag atttatgctt atagcatgtg cagcaatgtg ttgttttata
   107761 gaaccactta caagctgggc attaggtgat atatgtatag gtgtattaac atatataaat
   107821 ttaattgcca tctttacact aaaaaaacca gctataaagg catattatga ttatataaga
   107881 cagaagaaga tgggaataaa aaggagtgat agaactttta accctataga gttagatata
   107941 agaaatgctg agttttggga aaatagatac ttaaaagagg ataagcatga gttaaattaa
   108001 agttataata aaatataaaa attactaaat aaatttagtg ggaggtaaga ttggtatgaa
   108061 agaaagaata atacaagtgg ctgattcaaa gaaagaaaaa attctagggc tatgtcaatc
   108121 tttatatgat gaaccagaaa ttgctttgca agaatataaa tctgctaaaa aaatatcaga
   108181 atttttaaga gaagagggtt ttgatgttga ggaaaacttg gcaggtatgg ctacagcttt
   108241 taaagcaacc aagaaaaatg gagatggtcc taaaatagca tttatagcag aatatgatgc
   108301 tcttccaggc aatggacatg catgtggaca tcatttaatt gcatctatgg gagttggagc
   108361 tggaatagct ctttcaagta tactggatac ttacaaggga gaagtaagta taattggaac
   108421 acctgctgaa gaaactggag atggaaagcc ttacttgata gaacatggtg tatttgatgg
   108481 ctatgatgca gcaatgatga tacatccaaa ttcaaaaact tgtgtaacac ctgaaattat
   108541 agcaatagga ggtctagatt tcatatttac tggaaaagca tctcatgcag gagctaagcc
   108601 atataacgga ataaatgctt tagatgcagt agtactacta tataataata taaatgcact
   108661 aagacaacaa ttagtagatg gaacgagaat acatggtatt atactagaag caggaactgc
   108721 tgcaaatgta atacctgata tgggaaaagt aagattagag ataagggcaa aagaacaaaa
   108781 ttactttgat gaagtagtag aaaaagtgaa aaattgtgct agaggtgctg caatagccac
   108841 tggatgtgaa cttgaatttt atcactttga accaacttgc caaggattaa atgaaaataa
   108901 agttttggta gacatattta caaagattat ggaggaattt ggaatatatg aagatgaaca
   108961 agtaatgtta ggttcaacag atatgggaaa tttaagtcaa ataatgccat gtatacatcc
   109021 tttgatgaag ttttctgaaa atggagaaga actacataca aaagaatttt tggaggcttc
   109081 tataaattca tatgcaaaag atagagtaat tgatggtata aaaatattag ctttaacagg
   109141 atttaattta tttgaaaatc cagagttatt gaaaaaaatg aaggaagagt agaacttaga
   109201 ctatttttaa ttatactctt taaaataaga agagtgtctc aaaatgaact ttttagttta
   109261 tgagacactc ttttttgtat gaaattaaat atatttttat tattttaaca atgaaaaaga
   109321 ggcttatctg tttttatata acctttttta acttgtagca caaaatatca tgaatgatta
   109381 caattcgagt gataaaatcg attataagat atataggagg ggtacatatg gaaactttag
   109441 aagtaagaaa tattgaattg agtggtacaa attatgagat aggatacaga ctaggagaat
   109501 tggttgctaa tatgccagag atactagaag gtcagattaa taaatctaat gtggtaagca
   109561 aaaaagaaga aaaagagatg atagagttgt ttgataaata ttgtccaggt cttaatgaag
   109621 aattgcaagg ttttgctgat gcaattcaag tgaattgtaa tcaaatttta tattatacta
   109681 tgacttatct taaaccaggt tgtagtcaag ttgcattagc accagaatta actgaaaatg
   109741 ggcatgtact atttgcacgt aatttcgatt tctcacacaa tatggaggat tttgttttat
   109801 gtaaaactaa ggtaaatgga aaatatgcac atataggtac taccgttatg caatttggaa
   109861 gaggtgaagg tatgaatgaa tgtggcttag gtgtaagtca gtcatcatgt ggtattcctg
   109921 taggcaattc agatggttta agaaaaccag caattgtagg tttacagttt tgggctatta
   109981 ttagatattt gttagaaaat tgcaaagatg tagatgaagc attagaatat ttaaaggata
   110041 tgccaattgc atacaatatt aatttattgc ttgcagataa gtctggaaac attgcacttg
   110101 tggagacttt agatgggaaa aaagaagtaa atataatcaa tagtttagaa agtaaaagag
   110161 aatatttttt acactctact aatcatacac atattgataa acttcataaa ttagagccac
   110221 aatcaatgaa aaattctatt catagatata aattaattaa agaatatata aataagtcta
   110281 aaaaaattgg agagaaagag ttaatgaatt tattgtcttc aaaatatcca aatggcttat
   110341 cttgtaatta ctataatgat ttttttggaa ctttaaaaag tatagttatg gatttaaata
   110401 taggaaagtt taatatttta tggggtggac tagagaataa atgggagagc tactatttaa
   110461 aaaatgacat taaatctata acacagagga taaacataaa tattgaaaaa gcaccatctg
   110521 acttttttga tttcattgaa taaaaaatgt attcaattat tctaaataat taggacatat
   110581 aaatcaacta aaagttttta tttatcgtat tgaattagtt ataatatttt agtatagtaa
   110641 aaaatagtgc tattttacat atttaaagag tttaagtaga agagaggtgc catattggat
   110701 tacttaaagt attttgaaaa agctgtaatg tatattgaga ataatttaca tgaaaatata
   110761 actgtaaatg atgtggcaaa agaaactgga tattcttatt atcatttaac acgcttattt
   110821 aagtctatgt ttggtgaaag tgtaggaagt tatataaaaa aaagacgatt agtaagtagt
   110881 acaaaagaac ttttatatag tgataaaaaa gtgatagata tagctattgg tagtggattt
   110941 gaatcttcag aagcatttag cagagcattt aaatctatat acaaggttag ccctatagaa
   111001 tatagaaaaa atagaattga tgtatttgtt ggtaaaaaga aaaaattaga gttagatttt
   111061 atgagacatc ttgttggaaa tataacgatt aaaccagtta taaaagaaat agaaaaaata
   111121 aaggtaatag gtataaagga taaagtaatt ttagaaaata attcattacc tgacttgtgg
   111181 gagaaattca gaaaagtaca tcatattgtc ccaaatactt tgccatcaaa gagagttttt
   111241 ggaatctgtg aagcaatctc tgaaatacac ctagttagtg aaagtatgga atttaatgag
   111301 ataataggac ttgaagttaa tagttatgat gtgattccaa attcatttgt ttcaaaaact
   111361 attaaggaag gaaagtatgc tatatttact catactggta gcttagataa tttagacaaa
   111421 acttatgaat atatatgggg tacttggttt ttaagttcaa aagaagaact tgatataaga
   111481 gatgattttg aagtatatga tgaacgattt ttaggtccta gtaatgtgaa ctcacaaatt
   111541 gatatttata tacctataaa ataatctata agaaaactaa aaaataattt gattaagaaa
   111601 tagatgttcg taaaagagca tctatttttt atttttatca gatttagata attttaataa
   111661 taaaagaaat aaaaataagt tcttaaattt ctaag
//
LOCUS       DAEORM030000005       110328 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.005, whole genome shotgun sequence.
ACCESSION   DAEORM030000005 DAEORM030000000
VERSION     DAEORM030000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 110328)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 110328)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 110328)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..110328
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.005"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            complement(158..997)
                     /locus_tag="KRH23_000510"
     CDS             complement(158..997)
                     /locus_tag="KRH23_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HHS5223806.1"
                     /translation="MSDIKNEVSKKTLSKKDVIKSWLRWFFFAQSNYNYERLQSTAFS
                     HSMLPVLKKLYPDKEELKQEVETHLAFFNTEPICGCVIHGITIAMEEEKANGADEISG
                     DGMNAIKTGLMGPLAGIGDTLTQGVITPIVLAVCIGLTEGGASIAGPILFVIAQYIIM
                     TSISFGMWTNGYKYGKKAVESILQGGIVNKVIEGASILGTLVMGGLVGRFINLSTPIS
                     YTSGDFKFSLQTDLLDKIFPGLIPLVLTLLVLFALKKGLSPIKIMFILIVVGAITGIL
                     GLF"
     gene            complement(1021..1779)
                     /locus_tag="KRH23_000511"
     CDS             complement(1021..1779)
                     /locus_tag="KRH23_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HHS5223807.1"
                     /translation="MHISLIQAVLIAIFYYLSWSPWLTYVGFFTWNRPLLAGFVTGII
                     LGDPVQGAIIGAGINMIYLGFISAGGAQMGDPAFAGYVGTALAIASKLDVSTAMAIAV
                     PLGTVATVLWIGKMTVNSFFAHWADREVQKGNVDRVAFINIVPPQILLFAMSFIPALL
                     VVYFGPNAIDGMLEVMNDNVLHVFNVIGAMLPALGIAMNLKLIGNKFTMPFFILGILM
                     AVYFKVDIIVISVIGVILALTITSIKYGKDSATS"
     gene            complement(1826..2299)
                     /locus_tag="KRH23_000512"
     CDS             complement(1826..2299)
                     /locus_tag="KRH23_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HHS5223808.1"
                     /translation="MSNIALTRIDDRLIHGQVITTWCKITSAKRIVIVDDLVVKDPFI
                     VQVLQMAAPSTVKVEVHDVESGAEVLKSHNGDENLIVLVKYPKTVLGLVNSGVDLKEL
                     NVGGMGAGLGRKSFYKNISVSDEEKEIFRELISKDVKCFIQIVPDAKKIDVGTLL"
     gene            complement(2328..2744)
                     /locus_tag="KRH23_000513"
     CDS             complement(2328..2744)
                     /locus_tag="KRH23_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HHS5223809.1"
                     /translation="MIHMAGIIIATHGNMAKAMLESAELIVGKQENVETLGLNHGDSI
                     DEFSRKLEDGIEKYKDEGVLVLLDFYGGTPFNTSAIIINKFAKVCELECLTGVNLPML
                     LELFLNRDTMKLKDLKNLCEEVGISGIKDVKTVLKL"
     gene            complement(2791..3843)
                     /locus_tag="KRH23_000514"
     CDS             complement(2791..3843)
                     /locus_tag="KRH23_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HHS5223810.1"
                     /translation="MKSVRFYGIRDTRVEDVDVPKILEKDDVIIKVKVAGICGSDISK
                     YSKTGPHMVGEILGHEFSGEVAQVGKEVRSFKIGDRVAVCPAMPCFECDECKKGLYSR
                     CNNVAIIGNKELGGCFAEYTKVKERNLIKIPDEISYETAAALEPVCIAGHGLFRSEAK
                     VGDTVVVLGTGPIGLFSIQWAKIFGSTKVIAVDVFDEKLDLAKELGADICINAKEKNI
                     VEEIKRLIDGYGADIVIESAGTPLTCGQVLLLAKKGGTVLYAGVPYGDVALTREQFEK
                     IVRSELTVKGTWFGNSFPFPGKEWSAGLYHMQKGDMNVEKLVTHRINLEEVPAYFEKV
                     YKRDIFFGKIMINIDN"
     gene            4239..4919
                     /locus_tag="KRH23_000515"
     CDS             4239..4919
                     /locus_tag="KRH23_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HHS5223811.1"
                     /translation="MKKVYQGKTKDVFELDNGNYLLKFKDDVTGKDGVFDPGENSVGL
                     SIDGIGRANLETSVKFFEILNNAGIKTHYVSANLEEATMEVLPAKVFGNGLEVICRYR
                     AVGSFLRRYGSCVEEGAKLDCYVEATLKDDDRCDPLITSEGLEALNIMTQAQFDSMKS
                     MTQKISNIVRDTIAEKDLELYDIKFEFGFYNDEVILIDEIASGNMRVYKDGVIVDPMD
                     LTALLLDK"
     gene            complement(5052..5372)
                     /gene="sugE"
                     /locus_tag="KRH23_000516"
     CDS             complement(5052..5372)
                     /gene="sugE"
                     /locus_tag="KRH23_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="quaternary ammonium compound efflux SMR
                     transporter SugE"
                     /protein_id="HHS5223812.1"
                     /translation="MKWLFLFVAGLFEVFWAFQLKNSHGFSKLTPSILTVVGMIVSFY
                     FLSLALKHLPLGTSYAIWTGIGTVGTAIVGMAILNEPISISRIACIGFIVVGIVGLKL
                     LSTN"
     regulatory      complement(5442..5548)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00442"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="guanidine-I (ykkC/yxkD leader) riboswitch;
                     Guanidine-I riboswitches control genes whose products are
                     involved in modification or pumping out guanidine as a
                     toxic compound from bacteria; This is class of guanidine
                     riboswitches is based on the ykkC/yxkD leader; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="guanidine"
                     /db_xref="RFAM:RF00442"
     gene            5754..6581
                     /locus_tag="KRH23_000517"
     CDS             5754..6581
                     /locus_tag="KRH23_000517"
                     /EC_number="3.5.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-nitrogen hydrolase family protein"
                     /protein_id="HHS5223813.1"
                     /translation="MNFYKIAVCQMITTENKIENINHAVDMVTEAAINGAKIVVLPEM
                     FNCPYENKYFPKFAEEYPGETTTILSKLAEKHGIYLVSGSIPELEDGKIYNTCYVFDK
                     NGALIGKHRKMHLFDIEVTGKVSFKESDTLTAGNDVTVIDTEYGKVGIAICYDIRFPE
                     LSRLMALKGAEIVILPAAFNMTTGPAHWELSIRMRALDNQIFYVGAAPARNMNASYIA
                     FGNSRISDPWGRIIAQADEKECIIYADIDRDLIPDIRQQLPLLKHRRTDLYELNTLK"
     gene            7403..8077
                     /locus_tag="KRH23_000518"
     CDS             7403..8077
                     /locus_tag="KRH23_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HHS5223814.1"
                     /translation="MNNKILVVDDEEGIITLLKDYFEMNGYEVYTAQSGKDALKKISK
                     NPDIILLDINMPEIDGIEVCNRIRDYVSCPILFLTARIENTDKINGFRAGADDYIVKP
                     FDLDELGARVSAHLRREQRKSNQTKIKFYNDLTIDYEKRLICIYNNQISLSKKEFDIV
                     ELLSMNPGQVFDKEKIYDRVWGYNSNGNSDVIMEHIRKIRIKLSKHTLENYIETVWGV
                     GYKWIK"
     gene            8065..9225
                     /locus_tag="KRH23_000519"
     CDS             8065..9225
                     /locus_tag="KRH23_000519"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HHS5223815.1"
                     /translation="MDKINNMSLKKAFFVLTLSSLIIASVLTTFAYILLNNLYNSIQD
                     KYLKTPINTGIITIVQNNVNQFSDYDKTLLNIINILQLVLPLIFFIGLLLLADIIFYK
                     VKLKTPIEILNKGAMEISNNNLDFCLEYNNNDELGNLCNAFEKMRSELNKNNIKMWTM
                     INDRKQLNAAFSHDLRNPLTVLKGYSNYLTKYIPTGKLSDEKILSTTQLMSEHINRIE
                     YYVENMSNAQRLEDLVVSKSMSNINKFIENLDENISIIAKQEGKSFTLKSQINNINLF
                     FDENIILRVVENIISNAFRYARNNVSILIYLEQELLTFVIEDDGIGFSKESLKLALRP
                     FYRDKTLNDSNAHFGMGLYISKILCEKHGGSISIENNSTNSAKITAKFSTRN"
     gene            9463..9969
                     /locus_tag="KRH23_000520"
     CDS             9463..9969
                     /locus_tag="KRH23_000520"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: protein motif:HMM:NF013250.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HHS5223816.1"
                     /translation="MTFSRIVFALLMLSSTFSSLPFWICYFWCGISDILDGLIARKLR
                     QQSGIGAKLDSIADFVFAVTILVTVGKNIALPMYLWWCIVAIALLRLISYSIGFFKYR
                     TFSSLHTLMNKITGISIFAFPLLYICFGLDVAGIMICIVAFLSSFEEIAIMIKSKELN
                     RDIKSIFM"
     gene            10255..10923
                     /locus_tag="KRH23_000521"
     CDS             10255..10923
                     /locus_tag="KRH23_000521"
                     /EC_number="7.6.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHS5223817.1"
                     /translation="MIIKAKQLSKIYGSNNNKVIALNNVNLEINSGEFVSVIGPSGSG
                     KSTLLHILSGLDNPTSGQVLLDDKDIYKHTEKELSALRRKSFGFVFQQFNLLPVLTAS
                     ENISMPVLLDKKQPDKDYLNEISSLLGIADRLNHLPHELSGGQQQRVAIARALIAKPD
                     IIFADEPTGNLDSKSGSEVMNLLIKTSKQFGKTLVVITHDDRIAKLADRKISIIDGVL
                     MEVK"
     gene            10926..13394
                     /locus_tag="KRH23_000522"
     CDS             10926..13394
                     /locus_tag="KRH23_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHS5223818.1"
                     /translation="MKNYLSLSIKELKSQKLMTTFIIIAIVLSTIMTTVVGQSIGILQ
                     NLRIEQARSFNGDRHVSFHQLTKNQVDDIKKDDRVYQAGTSITIGSSKIKDSGISVLV
                     KEYDKTGLSNYPKLMKLKSGHLPKDKNEIALDENTLKLMGIKPRLGVTIPMNLDISLL
                     NDTIPPYNYTANFKLSGILEDDYTGYVSGIVNGIVGKGTSENLLPKRYILSSLDFKIK
                     QQEKFQEIVNQLAKKINLSHNSIQYNWIYLNALKIQFEKDENSSNSDGISMIILVSLF
                     VALLVLLASGLVIYNILKISVTKKIKEYGCLRAIGAEPNQIYKIVILQILILCTVAIP
                     IGAVIGIISSKGITGMVTNILNPDILLANDNKEITELIHKNTTAYMFPLVLSTNVSLI
                     FSFISALPSAIYASHVSPKIAMVGSTTKIKRKIKREKTIKNFERHLAWLNLKRNKGRT
                     IITILSLFMSITVFVALSEFSNVLDVSRSVSNLKEGDFSLTNELSGFDKSTLDKIAKM
                     KNVNRTSFIKYSEYKQGEIDTDINFENSGEMLKIIGIDEQTLKDLMPSITNSILEDFK
                     NGSICFIKNPIAISTPGVKTRHTNLKPKDSITINKKQLDIYSTVDKMFFLQGNGWING
                     VDVIVYDSVYNTLTNKNKFNQINIYAKDKSKLEQIRLSIEQICENNPGSHWISYIESD
                     KQLKESFKQIEFLAWAVILFVGLIGTLNIINTTHTNINTRTNEIGVKRAIGMSNSSLY
                     KMFLWEGVYYGIFAAIFGSIAGYASAIIINMATIEKFDFTNIPITSILQATIISVLAC
                     IIATLIPLRKVKKMNIIDCIDINL"
     gene            complement(13634..15058)
                     /locus_tag="KRH23_000523"
     CDS             complement(13634..15058)
                     /locus_tag="KRH23_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HHS5223819.1"
                     /translation="MKNQSLIAQFRHTFIFIIIASIVATVITYIFAIYLYIYSLNKDI
                     YPPNYYERQVPRIEKYINEKNIALLSQSNEEGLKRTIRGDDMLYQVVDNNGNILYGTN
                     PKKLFKTKEELFNNFINRTVRKGGYIHTVPIKGDNGKIEGAVILFYQVKITFANIRGR
                     FVFAVIIMALFSPFLYIVGFTRWLSKRFVKNINQPLHLLIDASKKIKEKDLDFEIDYY
                     SDNELGKLCSAFSEMKDELKGSLSAQWKMEQERVEMVEALAHDLKSPLSIILGYTDAL
                     IGNNTDDNEKLHRYLTVIRENTEKSAALVQKMQYTSDLEKSNIQLNLVPINLPEFLRQ
                     KVQDYELQAHQKEVELILKMQGNIQSPIQIDVDRLTRIFDNIISNSLQYTPSGGNISI
                     TVKDEKNCISYEICDSGRGFSSKDLKKALDKFYRGDEARQTKGGHSGLGLYIVKQLVE
                     QLGGSVKIENSKSGGACVKFWHSI"
     gene            complement(15077..15769)
                     /locus_tag="KRH23_000524"
     CDS             complement(15077..15769)
                     /locus_tag="KRH23_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HHS5223820.1"
                     /translation="MSKILIIDDEMDLVMLLEDELKAKGHEVLIAYDGQAGIELSKQE
                     PDLIILDIMMPKMNGFEVCQAIRDDVLCPIIFLSAKQSETDKIKGLTFGGDDYVTKPF
                     GLRELMARIEANLRREKRSQYINEENKRSTLYFGKLCLYMKERAIKIDGKNIDLTKIE
                     YDIVELLALHAGQVFSREQIYEKVWGCDSEGDSSTVVERVKKIRAKFSAVTPEKEYIS
                     TVWGIGYKWNKM"
     gene            complement(15821..16600)
                     /locus_tag="KRH23_000525"
     CDS             complement(15821..16600)
                     /locus_tag="KRH23_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutG family
                     permease subunit"
                     /protein_id="HHS5223821.1"
                     /translation="MIKLLSSEWLRAKRTAVQWLTLCMPIIFSLCVVFYLTTKSGSTQ
                     EFAFEGFFTVWTVFIIPIGVGILAGFIVQEEELAGNFNGFLCVGISRVRLYLGKFLFL
                     LFCLTICTFIATLILCIGMSIAVPSGATIWLFLSAAGLVVIGTLPLLAIHLWVSFAWG
                     MGASIGISIGGILMAAILGLTSVGEKVWAFVPWTWPVKLGMFPGIYFIKEAETISTEA
                     FYSKVMQTASIELIVVAIGLIIFLIGGVIWFKMWEGRKSYE"
     gene            complement(16597..17367)
                     /locus_tag="KRH23_000526"
     CDS             complement(16597..17367)
                     /locus_tag="KRH23_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutE/EpiE
                     family permease subunit"
                     /protein_id="HHS5223822.1"
                     /translation="MNALQSELLKYKRTFMGKLIVFFPVSFAAYAFIMQSTLMQNPLS
                     QTTSWAWQNLLALIFNWWSFLFLPIGFALFATLVAFQEKKAGNYRALRTHNVSPMTLW
                     INKVIAMAVYSFISTLVLIFVTIITGLILKAGSVPFGQIIGASIVCWVVSLAILPLQL
                     WLATWKGMFLSMGVGALGMIFGVLAATKPFWIAVPWSWAVRMVCPIINIHPNGTVLEA
                     GDPLLNTSVIPIGIVVSLVVFIVLTALTAAWFNRRDDK"
     gene            complement(17364..18068)
                     /locus_tag="KRH23_000527"
     CDS             complement(17364..18068)
                     /locus_tag="KRH23_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014466355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic protection ABC transporter
                     ATP-binding protein"
                     /protein_id="HHS5223823.1"
                     /translation="MKDLILETKNLSKRYGEQMAVNNVSLQIERNSIYGLLGPNGAGK
                     STTLKMLVGLLRPTDGRIIFDRKPWKRESLAKIGSLIESPALYGNLTAEENLLVHTKI
                     LGIPKDKIYEVLEIVNLKNTGKKRASQFSMGMKQRLGIAIALLSDPELLILDEPTNGL
                     DPFGIQELRELIASFPKKGITVILSSHILSEVAQVVDNIGIINGGRLLFQGMPDPNEN
                     LEEFFTDVILKGGQNR"
     gene            complement(18323..18835)
                     /locus_tag="KRH23_000528"
     CDS             complement(18323..18835)
                     /locus_tag="KRH23_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5223824.1"
                     /translation="MKKISQEKISTHIQEVPQEKIEQWKSLYEKYKSILKVNSKSVLE
                     IIEFLKRKYVIVEETSEEFKHVVINNIKLNKPFSQKISSDKELKPIVFTIPNEGNAKK
                     LYDTQEETYSGCKIIVGMEFETGCVFVEGSDELNDEITSFKGLDKYDINNYYLVANYI
                     RCLKKYKLID"
     gene            19161..19415
                     /locus_tag="KRH23_000529"
     CDS             19161..19415
                     /locus_tag="KRH23_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5223825.1"
                     /translation="MILNRTELFRGCSLNRFNEICNILSVNKIKYKYKVKNNAYSKKP
                     FFNEITLGNLGQKEDFFYEYLIYVHKDDYEQAESLINSKL"
     gene            19561..20187
                     /locus_tag="KRH23_000530"
     CDS             19561..20187
                     /locus_tag="KRH23_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HHS5223826.1"
                     /translation="MKINIKSKLSEFIKQNNLFDDSRIISYLPNITIETDKIKTIMIN
                     EVVPTNTNDDFYSVDKDADYLKTTIPLFDSAGIKVSNINDILDMGIYITNAVKLPKSE
                     YTITRDTIKLHMPILEEEIKLFKNLEVVMLMGDVAKKSFNMITKKHIKKNVIPSISTY
                     KLRNNELYYDNLRVFPSYIMTGGNILIEKSKFEMASEDIKKMFEIING"
     gene            complement(20434..21213)
                     /locus_tag="KRH23_000531"
     CDS             complement(20434..21213)
                     /locus_tag="KRH23_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901940.1"
                     /note="N-terminal region resembles flavodoxins. C-terminal
                     ferrodoxin region binds two 4Fe-4S clusters; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EFR1 family ferrodoxin"
                     /protein_id="HHS5223827.1"
                     /translation="MNSKIYYFSGTGNSLVVSNILKETLNGSKEVIPLAIHRKENNID
                     INEDILVIVFPVYFADVPDIVKSFVEKLNFNINTHIYAIATCNGVAGHSLFTIDKLLK
                     KRGKKLSAGFLINMPGNALITPPDVEEERLKNQTNRVAEIAKCINNLEIGNIEGKNNL
                     KSHIDSVVLRLVGKNMQIATTKFFAENKCNGCGTCKRVCPVENISIVDKKPKWGNECE
                     RCLACFHWCPKEAINVKKSFLTNRKKYHHPDITVKDIFLGK"
     gene            complement(21281..21706)
                     /locus_tag="KRH23_000532"
     CDS             complement(21281..21706)
                     /locus_tag="KRH23_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HHS5223828.1"
                     /translation="MKDFEKLYEATTKLVSTSLKVKDDLKKMFKQNGYDITTDHYALL
                     RFLWEQDGISQIDLCEKSCKDKSNTTRILDVMKNKGLIVRKVDVKDRRKFQIFLTDLG
                     RELEEPLNEIASIYATETFKSISDEELPLFTDILDRIGK"
     gene            complement(21718..22395)
                     /locus_tag="KRH23_000533"
     CDS             complement(21718..22395)
                     /locus_tag="KRH23_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HHS5223829.1"
                     /translation="MIITVVNGSPRKNGATSKVLTYLYKDIERLIPDVKINYFDLSEV
                     NPSYCIGCLNCYKMGKCINQNDKVEYIHDIITKSDGVIFGSPTYGSSVTGLFKVFTDR
                     AHMMLERLLYRKPCIAVTTYENARGSKAISFIKSMVLDSGGYVCGSLSIKTGFNQNPI
                     TEKVESKIQKVSKKFIYCIEEKKNPPVLSQIYNFIAINAVLKPMAFKDIEQYKGIIDR
                     WEEQGII"
     gene            22628..23014
                     /locus_tag="KRH23_000534"
     CDS             22628..23014
                     /locus_tag="KRH23_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HHS5223830.1"
                     /translation="MKKLPHISEAEYQVMKIIWKYAPISTTEVIEKLVETSTWSPKTI
                     QTMLLRLVKKGALTYEKNSRVFVYTPLVKEEEYVAKESSSFLNRFYNGTLNSMVLNFL
                     ENDKLSEDDIEELREILNKRTTKGDK"
     gene            23017..24816
                     /locus_tag="KRH23_000535"
     CDS             23017..24816
                     /locus_tag="KRH23_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BlaR1 family beta-lactam sensor/signal
                     transducer"
                     /protein_id="HHS5223831.1"
                     /translation="MYVPFFIRFLLSTLTLSILIVVILLAKKVFKKHISAKYQYNIGF
                     ILLIMLIIPFVPLKYINLGNVFNYLYTFNQLGSNTNRASMIKNSPNSIINNSNALNDF
                     SVSLNQVNFDSLNILLLISWIIGILIMIAITIHCNIKIKNMKKSIQILRDDEIVFIFE
                     KCKKDIGINKDFILCKSPIINTPITFGYFKPHIILPDKSISKLSLKDIKYILLHELQH
                     FKNKDILINYIMCFLQILYWFNPLVWYAFKEMRIDREIACDISVLKNLDKDSHIEYGQ
                     TLINFVDNISRPSNLTLTSDIGGSKKQIKKRLLKIMDFHNESNTLKFKSILIFTLIAL
                     IVFGNIPKLSIMADINEKYRPTNEQTVYEDLSQYFKGFDGSFVMYDLKSKQYHIYNKE
                     KSKTRISPNSTYKIYSALLGLENGIITRNNSHIPWDGKHHSNSSWNEDQDLFSAMENS
                     VNWYFQTLDKKTGLKNIQTYLRQIGYGNYDVSGGISNFWLESSLKISPIEQVELLESF
                     YTNKFKFEDKNIETVKDSLLISKKDGVSLFGKTGTANINGKDVNGWFIGYVEKNENTY
                     FFATNIQSKDYSNGSSASKITLSILNDKKIYNP"
     gene            complement(25171..27045)
                     /locus_tag="KRH23_000536"
     CDS             complement(25171..27045)
                     /locus_tag="KRH23_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose PTS transporter subunit IIA"
                     /protein_id="HHS5223832.1"
                     /translation="MNKYNKIANELIKIIGEDNIISITHCATRLRVMVKDREIINDKK
                     VEKVDEVKGVFFTSGQYQIILGTGIVNKVYAEVEKMGLKTLSKKEQDELVKNNETGFK
                     KVMRTLADIFVPIIPVIAATGLFLGLKGCLFNDNVLGLLGMSSANIPLYIQTLVSVLT
                     ETAFAFLPAIIVWSAFKVFGGTPVIGLVIGLMLVSPILPNAYSVADPSNEIEAIMAFG
                     FIPIVGCQGSVLTAIVTAFIGANLEKWFRKHMPNVLDLIFTPFFVMLITMLVILLGVG
                     PIMHTIELKMVDIISLLIDLPLGIGGFIIGFTYPLAVITGLHHTYVMIETSLLANTGF
                     NALITLCAMYGFANIGTCLAFMKKSKNNQVKQTAVGAMLSQLFGISEPVLFGIQLRYN
                     LKPLIIMCASSGLGAAILSILHIQSNSYGLAVLPSYLMYIYDGYNLITYLLVSIFVVA
                     FCFIVTCLFGVPKEAINEDEDEELVFNENNENFVSPAKGKIVALENVPDETFSKKMLG
                     DGFAIDIIDGKIVSPISGKLETVFSSGHAFGIKGTNGEVLIHVGIDTVALNGDGFDVA
                     VKQGDMVKQGDVLVNVDLKRIHELGKSTLTMVLFPDGKKVNILDINKDVKIGQRICVE
                     "
     gene            complement(27050..28714)
                     /locus_tag="KRH23_000537"
     CDS             complement(27050..28714)
                     /locus_tag="KRH23_000537"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_function: GO:0004556 - alpha-amylase activity [Evidence
                     IEA];
                     GO_function: GO:0004574 - oligo-1,6-glucosidase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009311 - oligosaccharide metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 13 protein"
                     /protein_id="HHS5223833.1"
                     /translation="MEKKWWQKEIVYQIYPRSFQDSNNDGIGDLQGIISRLDYLKDLG
                     ITSLWLCPIFKSPMDDNGYDISDYLDIASEFGSMEDLKELIKESKDRGIKIILDLVLN
                     HTSDEHPWFQEALKNPESSYHDYYIFKKGNDLPNNWRSVFGGSVWEKVENRDEYYFHS
                     FGKKQPDLNWENPILRSELYQMINTWSQMGVAGFRVDAITFIKKNLSFQSLESDGVDG
                     LVKCTKTVRNQPGIEKMLYELKENTFKKYDCMTVAEAAGISYDQLGDFIGEDGFFSMV
                     FDFKHADLDVASGSEWFKRISWTIPDLRKCILDSQMYVQEHGWAANFIENHDQPRATT
                     KYLLQYERNDDAVKMLGAMYFFLRGTPFIYQGQELGMTNFKRDNINDFNDLSSIDQYY
                     RSIDEGYSEEEALEFVNLRSRDNARTPFPWADKENAGFSDTTPWLKVIENYKDINAQS
                     QINNSESILEFYKKMIKLRQDSEYSDCLIYGSIEPIDIESDDVIAYRRQLDLVVIDCY
                     YNFSDKPVEIRVEEKYDIVFQNLDDINPLNKTVRLKPFHAILLKAR"
     gene            complement(28728..29549)
                     /locus_tag="KRH23_000538"
     CDS             complement(28728..29549)
                     /locus_tag="KRH23_000538"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HHS5223834.1"
                     /translation="MKLYKLLILDIDGTLRDEVYGIPESAKHAIRLCQKNHCSVVICT
                     GRSMGTIQDDVLSLGVDGYIAGGGNYIQYHGELLYNQSFNQRLIKEVVCLLKKREVAF
                     SIESQEKVFMNQKAKEIFETMNQLKGTNSCINKQHIQEKITYENNIEEYKSQDIHKIC
                     LWSNEKVFDEVKDILQDKMELAQRDISSQYYEIIQKDFHKGKAIKRLQERLGVTQKET
                     ICFGDGQNDIVMFQASDVTIAMKNSHQQLKDIATSICEDIFDNGIYKELKRRNII"
     gene            complement(29648..30412)
                     /locus_tag="KRH23_000539"
     CDS             complement(29648..30412)
                     /locus_tag="KRH23_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HHS5223835.1"
                     /translation="MKIEGLFNKYYNSFTANDKYICECILNHKEDCIKLSIDEFADKY
                     HISTSALSRFAQKLQLPGYSELRVIIRLNETEVEYKNQSKHQLMDCYNKVINDIEKKD
                     CSIMFERMKKANRIIVFGEGYSQERVAKEMKRIFLPTGKIIYDVYGYDMIQALNHFIK
                     TDDMIFFISLNGDASTIIDFAKEMRMKGIYMVSITKMISNPLARLCDENLYIQSISIS
                     VDKQLDYDVTTPYFILIELLYIKYKMYLESEHIPRK"
     gene            complement(30409..31158)
                     /locus_tag="KRH23_000540"
     CDS             complement(30409..31158)
                     /locus_tag="KRH23_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HHS5223836.1"
                     /translation="MRLESLVNQNYDNLNENDKIIIKQILICQREYRNFSCEKIANEC
                     NVSRATLLRLCRKIGLDSFSDLKYLLKNNQLEFVNNDNNFHDVCENYRLLMNELQKIS
                     FQDICKIIYDAETIYIYGTGNEQKSLAQEIKRIFLSVGKCVIDLFDIGEIEFMRESFQ
                     KSDLFIIISLSGETKAGIEIAKFINNHIHTISLTRLDNNTIATLCEYNLYVETQKLDT
                     LQAISYEVVGAFYALLDLLHMNYIEYRRRKE"
     gene            complement(31440..32492)
                     /locus_tag="KRH23_000541"
     CDS             complement(31440..32492)
                     /locus_tag="KRH23_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHS5223837.1"
                     /translation="MNVINVFNSNLKRNINKRIVFLVTLLFPIIIVVLGVLANYISKP
                     SFNIGILDEYKNECILKESEKRTYENTIMALENTQGINTEIADFKTIKTDIITGKYSA
                     VVCFNKNGFELYSIKDKNTNDTLKYLIETYKKDPVPVDISKLQENTLGVLQRIIAFIV
                     LFLMITSTVTASMIIKDKNSGTFTRVLYSPQNIRGYVLGNMLYNFTITYFQYIVSISI
                     IKLFNIDISMDYIDLILMGVWISALATSFGTFVSSLFNKEMHANLFSTCISLILSLIG
                     GSFISVEKMPTMLQKISIISPTQWFISFVTYIEERDGSFFNMNYICILTFIIIILALL
                     AMKFTQRSKYSSNRNY"
     gene            complement(32492..33232)
                     /locus_tag="KRH23_000542"
     CDS             complement(32492..33232)
                     /locus_tag="KRH23_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHS5223838.1"
                     /translation="MRCFLTLFKLGIKRRSKDFFILFYNIVFPVIIIVLLGYLTSKSY
                     GKEFTSYNYYTIVTIPFCVLMGIISVSYVAQDEKISNTSYRYMISPVSIVDLVISKLF
                     SCTTVFSIYNLITLVVLRGIFHMSFGGKFLVVIFFLMCESIAVVSMGLFLGLVCKNLD
                     MLRNIINIPIVIFGFLGGVFFPVSSLNPVISLIINISPLTWINRGIVACIYDNNLQLL
                     FNISCIFVAVSIFMTILTIKFFKKEVFI"
     gene            complement(33237..33995)
                     /locus_tag="KRH23_000543"
     CDS             complement(33237..33995)
                     /locus_tag="KRH23_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHS5223839.1"
                     /translation="MSNVLLEIKNLSKKYNNKEVVSRESFKLLEGDILGFIGPNGAGK
                     STSINMLTTIVSPDSGSIYYKGKDIKNQQNIFKSSLGVVPQELAIYEDLSAYDNVKFF
                     CSLYGFKGNELKERIKYALEFVGLWESHKEFPSKFSGGMKRRLNIACAIAHSPQILIM
                     DEPTVGIDPQSRNKILEAIKGINNNGTTVIYTSHYMEEIETLCNRIVLIDKGVIIEDL
                     DKSLYKNKYLKFGCKTLEDIFLYLTGTDLRDLEE"
     gene            complement(34100..34822)
                     /locus_tag="KRH23_000544"
     CDS             complement(34100..34822)
                     /locus_tag="KRH23_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HHS5223840.1"
                     /translation="MIRTLILYYLNIKPTHGYEIQKFLQVSGADRWTKIQSGSIYYAL
                     AKLEKDGGVRVLKEEKTGARIRKIYEITQSGKLELREEIQKELQMPIVPTGSNKFLLH
                     NILDVLPKDTLQKNLEKHIKYLIEQKKYWENWKEIKKIDKKSLATEKIAFDMTIDNLN
                     YQILWHEEILNNIDKYISVGCETQNIIKSIDFSNIEEDFLFTSDTTNELLEVQRLRDE
                     IINNPDKAIENIDKIILKLQNK"
     gene            complement(34923..35312)
                     /locus_tag="KRH23_000545"
     CDS             complement(34923..35312)
                     /locus_tag="KRH23_000545"
                     /inference="COORDINATES: protein motif:HMM:NF012955.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HHS5223841.1"
                     /translation="MKEKTGAKVWAHVEDIPFIIGEKDRPGFKKFIGKAISRRLIKDV
                     EPYGENMQIGNIKIIHTPGHTPGHVCMIFEDVLFAGDLVKNKNGNIVPYPNPWNWDYK
                     KMIKSIRELDNLKYEWICMSHGTPCIK"
     gene            complement(35309..35527)
                     /locus_tag="KRH23_000546"
     CDS             complement(35309..35527)
                     /locus_tag="KRH23_000546"
                     /inference="COORDINATES: protein motif:HMM:NF012955.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HHS5223842.1"
                     /translation="MKIKENVLMLDSTRGSNCFIVFDKEIILIDTGLPFMGKNIIKEL
                     KTLGIKLTDIKHILLTHHDVDHISILNY"
     gene            35706..36344
                     /locus_tag="KRH23_000547"
     CDS             35706..36344
                     /locus_tag="KRH23_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HHS5223843.1"
                     /translation="MSELSKRDKEKIQRENEIIDKAEKLFCLNGFDNTTMNELAKEVE
                     YTKRTIYKYFSCKEDLFFAVVLRGYKRLWDNVKIESAKGKTGFEKIKLSYFAFHKFYS
                     VEPSLLCLMGMIGIVNSEKSDTDMLFKEKFFSFNKFMFDEIQGMFEIGKNDRSIRHDI
                     EIPTLMYSSIFTLTGFFNLLSVTGKSYLNNFNIDEEKFIETTLALLIDSIKA"
     gene            36476..37138
                     /locus_tag="KRH23_000548"
     CDS             36476..37138
                     /locus_tag="KRH23_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HHS5223844.1"
                     /translation="MAKILLLEDDDTITFGIKTSLEKKNHTVCCYNTIAEAKKNFDKT
                     IDLILLDLNLPDGIGYEFCQYVKSIEDTPVIFLTVRDDEKDIIRGLDMGADDYVVKPF
                     LLSVLQSRINAVLRRTHSNTNNTITCENISLNKVEVKAYLDNVEVPLTAGEYKLLLSL
                     MENKNRAMTRTKLLEMLWDVDGNFVNDNTLTVTIKRLREKLKNPPCIKTLRGIGYRME
                     DN"
     gene            37138..38319
                     /locus_tag="KRH23_000549"
     CDS             37138..38319
                     /locus_tag="KRH23_000549"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HHS5223845.1"
                     /translation="MKTPRNINSTVVFIIFCLIVTFLLTVILTTITSFNEYNVLSKAL
                     GASYEYNPKSTESILKSLKNSSDKDFKTGNEILSKHGYSKSTFWSKNFFYFLVISFGI
                     ISTMATVVYIIKHRTNKQKLSRINNLTQYLEEVNLGKESVLLRCEDEFSHLEDEIYKT
                     VGELRCSKEFALKERQTLSDNLADIAHQLKTPITSMSLMAQLLSENCPDEEIDYINRL
                     TNQISRLERLVSSLLTLSKLDASTLIFESKLIDVHSLLTYAIEPIEGSLREKHQTFTI
                     EASPSVEFEIDINWTLEALLNILKNCSEHIEDGGYIVAYYSQNPLYVEIIIEDNGKGF
                     AQEELPYIFNRFYRGKNASKDSIGIGLALSKSIIERQNGTIHAENCHNGGARFIIKFY
                     T"
     gene            complement(38500..41160)
                     /locus_tag="KRH23_000550"
     CDS             complement(38500..41160)
                     /locus_tag="KRH23_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHS5223846.1"
                     /translation="MNILQEYTLDFVRRNKRSSIAIMLAILLTTTMMSSLCGLLYTMW
                     TDFIKLSIEKEGNWHGELFDYTYGSDLPLIENFSSVDDVMVKGQWYVGKINDEKRDYI
                     IYRNATSEYWDSMPEKDTIIEGRRPNNANEIALSKQYFENNPSVKIGDKITLPIGDRI
                     LNGKPLEPIAPKSKGESFKKISEATLTIVGKVDVSTSSVIPAYTALGYLDKTSIKPND
                     SITVYLRFKNIRDTYKELPKLAKSLGWKTNEYGKYNLKYNSNYLLKMLVFSPEQKASM
                     SSISKFSTPIMYLTIAIFTVAVFVMVIYNAFSLSANARLTQLGILSSVGASPKQIKRS
                     VVFEGFLLTIIPLPIGLFLGWLLCNRLIVYVNSVNYHTDVPEVVFTYGIPAFLPAVLL
                     TIVTVWISALIPARKVSKISPIEAIRQGDSVKIKKSHKYSLGKIFGIEGELASNALRA
                     RKKSYRTATISLTLSFLLLTCFLHIIANQEGAKAVYGSDNYKDQRDIEVYLENSEPVE
                     SAFIEKLDNTEGVKSSLYYQKMSASTWLTEKDASKELAKNGGFKNIASSKKYSPIERD
                     GKFRIISNIIGLDDKSFTEYCRQISVDPKLFYDTKNPTSIVYNKEEDINRSTRRNKVY
                     IDYLNLSIGDNIKLNEKVYDEDKGDYTYNMKVGAITSTLPKIVDTSSKYTLMQIVPMS
                     MVQEISKNYDEVSRLRSNRLIGVFKVNNREDIPRVREKLESIYNKDYGSGDYSIEDVL
                     ESEKQKASGIKTMNLIVGFITGLLAMIGLSNVLATVSGNIRSRRQEFAMLRSVGLSPE
                     GIKKMLILEGLFLGITPLLLSIPVQIGIVYAFLRINEIYFIEYLPFAPISTIIGFTIL
                     ILFIVIASYMTGYKQLKNENIVESIKNETI"
     gene            complement(41157..41840)
                     /locus_tag="KRH23_000551"
     CDS             complement(41157..41840)
                     /locus_tag="KRH23_000551"
                     /EC_number="7.6.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHS5223847.1"
                     /translation="MEILKCENLTKIYGSNQTRVTALNNVNLSVQKGDFVSIVGASGS
                     GKSTLLHLLGGVDRPTSGKIYVEDTEISSLKEEALAVFRRRKVGLIYQFYNLIPTLDV
                     RKNILLPMLLDKRKVDEDRFSEIVSILGLSDRLNHLPSQLSGGQQQRVSIARSLIYRP
                     AILLADEPTGNLDRKNSEEIVDLLNLSNKRFNQTILLITHDEKIALEANRIVTMEDGV
                     IVSEKVVKK"
     gene            complement(42184..43110)
                     /locus_tag="KRH23_000552"
     CDS             complement(42184..43110)
                     /locus_tag="KRH23_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extended-spectrum class D beta-lactamase CDD-2"
                     /protein_id="HHS5223848.1"
                     /translation="MKRKNNFIWIVILLVVVAMGVYYVGRKHNNTKQKHDKNHINSEL
                     NKSKVENKKEKINMVDYSDCFEGISGGAIFYNTKNKEYNIYNKELIETRRSPCSTFKI
                     VSTLIGLEKGVINSKESVMGYDGTEYPNKNWNKNLSLEEAFKESCVWYYKKLIDKVDA
                     KSVQNILDDLKYGNCDISEWEGDLKNGKGHLNGFWLESSLQISPKEQVQTMAKIFEGD
                     TNFKKEHINILRDIMKIDVNDKNINVYGKTGTGFDEKNKRVDAWFVGMLEREGDTYYF
                     AIKSDDSNKEITGPKVKEIAINIIKKYYSVRE"
     gene            complement(43138..43854)
                     /locus_tag="KRH23_000553"
     CDS             complement(43138..43854)
                     /locus_tag="KRH23_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5223849.1"
                     /translation="MILIVILSIFIIASINIIILGKENIRDIVIPLTLFIVSDFLFLC
                     GNIICRGGVMLLFIGLFAIPLMLIAFIWICVHMIKLYYKKDLNKRKMIGCIFSIFISI
                     GTIFIPSPSESFRFKLYEKDYSVVAKAILKVYDEKKLSSESVFYIQSDKNELEKIFSK
                     EVIKKMKKLNRNLDVVKISGNRNLVYFFFGAELQSIDGIVIFKNLKHVKPKLDFINRS
                     IQAPRLEYITNNVYYFKGEL"
     gene            44186..46429
                     /locus_tag="KRH23_000554"
     CDS             44186..46429
                     /locus_tag="KRH23_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HHS5223850.1"
                     /translation="MSNIIIKGLTQNNLKNISFKIPKNKIVVFTGVSGSGKSSIVFDT
                     IAAESQRQMNETYSSFIRNRLPKYRKPQVELIDNLTASVIVDQTPLGGNARSTVGTIS
                     DLYSSLRLLFSRIGEPYIGTTSYFSFNDPNGMCKNCSGIGRVKVINIESIINPENSWN
                     TGCINDSLFKPNSWYWKQYAESGLFDLDKPIKDYSFEEYNLLLYGSKNKDGKQENPKI
                     EGIFNKYNQTYLNRDISNMSKHTKEKSERLITDKECPVCHGKRLNKETLNCNILGYSI
                     ADMCNMELTDLYDLLLQIKDKRTETVIKTLTDGLKRMIDIGLPYLHLNRESSSLSGGE
                     AQRLKLVRYMGSSLTGMTYIFDEPSADMHPRDVHRMNQLLKKLKDRGNTVLVVEHDKD
                     VISIADEVIDIGPSAGTQGGQVVFQGSYDKLLLANTLTSNAMNLSLPIKTDSRHPKGT
                     LPIRDACINNLKHIDVDLPVGIMTVVTGVAGSGKSTLISRVFAQKYEKDVIKIDQSPV
                     TATNRSMPATVLGFFDEIRKVFAKENNVEEGLFSFNSKGACPVCDGKGVLVTELVFMD
                     PIINTCEACKGTRYSEEVLSKLYKGKCIVDVLSMTVDESLEFFTEKKLCKILQTMKDV
                     GLPYMTLGQPLSTLSGGERQRIKLAKNLNKKGTIYILDEPTTGLHGSDIEKLMLNFEH
                     IVDKGNTVIIIEHNLDVLKQADWVIDIGPDGGKNGGQVVFEGTPLEMFERGCTITSDF
                     LRKSINI"
     gene            complement(46691..48805)
                     /locus_tag="KRH23_000555"
     CDS             complement(46691..48805)
                     /locus_tag="KRH23_000555"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HelD family protein"
                     /protein_id="HHS5223851.1"
                     /translation="MSENKQVVNCDIIASNSKHNMCEYDAELLTFFPDEIAHLIEINN
                     KLDNAFKKAENLVDKLDKDYMDAKMYMVKNRGEIDPHEMFQNEQGLKQIDNYGAFMVK
                     VRGKINKIKDSPYFARIDFRLKDMDDESKYYIGRFAFDYEDELIILDWRSPIASMFYD
                     YEIGKAGYDAPIGWVDGEITRKRQFKIKNGKLEYALESSINIQDDILQKELSHTSDEK
                     MKSIISTIQKEQNQIIRNDKADTLIIQGVAGSGKTSIALHRIAFLLYRFKDKISANNV
                     IILSPNKVFGDYISNVLPELGEEPLCELSFENIAEVQLDRVINFESEKDPLEINDAKW
                     SERVRFKSTLDFVKLIDDYIKQMPNKIFIPKDYTFGSFTAKSDWIQSRFEAYNRYPVK
                     KRLEKVAEDIHYKFESDNIMEEDLPKVKSILKSLNGMLTIKNTLTLYKDFFKQMNISN
                     MFVMVEKKTLEWSDVYPFIYIHAAYEGIQEDKIIRHIVIDEMQDYTPIQYAVINLLFK
                     CKKTILGDFGQLVNPNHTHTLDDMKQLYNDGELVMLNKSYRSTFEIINFAKKIQDISS
                     LEPIERHGEEPALLKCNNEQDEINKIKIEIEEFKKSDNATLGIILKTDNDAKAVYDAL
                     REEYSVHLISSESSSFTKGVSITSIKMSKGLEFDEVIVPSVNNKTYYSDYDHSLLYIA
                     CTRAMHKLKLTYVGTLTQLISM"
     gene            complement(48889..49725)
                     /locus_tag="KRH23_000556"
     CDS             complement(48889..49725)
                     /locus_tag="KRH23_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHS5223852.1"
                     /translation="MSYKVINVITAIDYIEEHLSEKLDLDIVANAVHYSKYHLHRTFT
                     TSVGLTMHDYIKRRKLTEAAKLLVFSKKPIIEIALIAGYESQQAFTSIFKAMYKKSPN
                     KYRKEQEFYPLQLRFVLKKDNLFLKNVLELEKEIKLASMSDIPLWMNLVRLVIDGFPN
                     LQEEEYIYQLEQYILEERALILKLNNVAIANMVFNRETRSIDFFGIHPQYRNSDIAQV
                     FLKKVIEDFLIDTDISITTFREGDKADTGHRDMIKKLGFAEAELLVEFGYPTQKFILP
                     LS"
     gene            complement(50320..50682)
                     /locus_tag="KRH23_000557"
     CDS             complement(50320..50682)
                     /locus_tag="KRH23_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HHS5223853.1"
                     /translation="MKIYDILTRFYIQDIEKAIPFYENLLKEKCSLRFSYKEVGLELA
                     QIGNVLLLSGSDDALKPFIETKSTFMVDSVDEWRSYLLDNGAVVVRDKKKVPTGYNMT
                     LRHPDGTIIEYVQHTKQD"
     gene            complement(50916..51380)
                     /locus_tag="KRH23_000558"
     CDS             complement(50916..51380)
                     /locus_tag="KRH23_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HHS5223854.1"
                     /translation="MTRISNITIAEQSEYCFLAIRKTIDFMVEFSEFSKQSFEKISKY
                     LEERGILSSGAPIVCFHNMDLAKLDVEVGFPVATYIDGKNEILQRIVPAQKIITAIDL
                     GPYELQDPTLEDLFSWANSNGYKLHGDIYYQYLNDINRPASEYLTKMMLPII"
     gene            complement(51809..53230)
                     /gene="nhaC"
                     /locus_tag="KRH23_000559"
     CDS             complement(51809..53230)
                     /gene="nhaC"
                     /locus_tag="KRH23_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA];
                     GO_function: GO:0015385 - sodium:proton antiporter
                     activity [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HHS5223855.1"
                     /translation="MKERECRKASLFDAMIPITCLILFLSLGVLVYGSSPHVPLIGAA
                     AVAGLVAVYRLGFKWKELELSMFNSIKMAMQAILIIIIIGVLIGTWIVSGVVPCMIYW
                     GLKILSPNIFLVASTLVCAIVSLATGSSWSTMGTVGVALLGIGQSLGMPIGLIVGSII
                     SGAYFGDKLSPLSETTNLAPAMAGTDLFTHIKYMLYSTIPSLLICLVIYGVIGMKYSG
                     QALDIKQIELIRSTLDSTFNTLSPVLLLAPAIVIGLVVFKVPAIPGLIVGAVLGVLFA
                     VVFQGESMNTILDAAQNGYVSSTQIQEVDALLSKGGIMNMMSTVSLTICALSLGGILE
                     KTGMLEVVASSLLRLAKGVFGTVLCTMVTCTITNIIAGEQYLSIVIPGRMYNKEYKKR
                     GIHPKMLSRALEDSGTLTSPLVPWNTCGAYITATLGVSALTYGPYALLNIINPIVSLV
                     LIACKFKIARIEDEPETCLNFDV"
     gene            complement(53260..54324)
                     /gene="orr"
                     /locus_tag="KRH23_000560"
     CDS             complement(53260..54324)
                     /gene="orr"
                     /locus_tag="KRH23_000560"
                     /EC_number="5.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine racemase Orr"
                     /protein_id="HHS5223856.1"
                     /translation="MYPRLEIDIEKLKHNAKLISQMCHERNIKISFVTKSFCAQKEIV
                     EEICSEGIDHIADSRIQNLKNLQDINLPKILIRIPMLSELEEVINYCDISFNSELGTI
                     KKLNELCESKNIIHKIVLMFDLGDLREGYFYEEDFFSNVREIVRLKNIEIIGIATNLT
                     CYGAIIPSRENIGRLVSIAKRMEEKFGINLEIVSGGNSSSIHLLINNNMPEGITNLRI
                     GESILLGRETAYGENINGTYQDAFKLICQVVECKEKPSVPIGEIGVDAFRNKPVYEDK
                     GILKRAIIAIGKQDINIDSLIPIDTDIKILGASSDHMILDVSNTKYDYKLGDNLEFLL
                     TYGGIMSSSTSKYVSKKIIV"
     gene            complement(54309..55718)
                     /locus_tag="KRH23_000561"
     CDS             complement(54309..55718)
                     /locus_tag="KRH23_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlmL-related ornithine degradation protein"
                     /protein_id="HHS5223857.1"
                     /translation="MENSKVSLKIDVLVAEIGSTTTVVNAFHDINTNNPIFLGQGQAP
                     TTVFEGGDVRNGLSGAIKDLANKLSVDDIKYNDMFATSSAAGGLKMTVHGLVYDMTVK
                     AAKEAALGAGAVIRQITSGRIKRTDLNKIKEINPNIILIAGGVDYGERDTAIYNAEMI
                     ASMNLGIPVIYAGNVENQEEIRLIFEDTNYKLYITENVYPKIDLLNIEPTRRIIQSVF
                     EEHITTAPGMKYIKEMVNENITPTPGAVMEASKLLYKNIGDLLTLDVGGATTDVHSVT
                     DGSDYINKILVNPEPTAKRSVEGDLGVYVNMKNIVEIIGKENLQSELSIDIDAVIENY
                     PPIPKSKEEILFVERLTKEAVVKAMLRHSGKIRNIYGTTGKVKIAEGKDLTEVRYIVG
                     TGGALTRLPSRIEILDNMLKYNKNNELLFPKEKTKILIDNDYIMASMGVLSKKYEEAS
                     LKLLLKSLNFEEERLCILG"
     gene            complement(55718..57922)
                     /gene="oraE"
                     /locus_tag="KRH23_000562"
     CDS             complement(55718..57922)
                     /gene="oraE"
                     /locus_tag="KRH23_000562"
                     /EC_number="5.4.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-ornithine 4,5-aminomutase subunit OraE"
                     /protein_id="HHS5223858.1"
                     /translation="MLKENKKLDIDYILKDLDKYKPKRRGWVWREHLENLEMGPFKYK
                     DCTKPLKKSVGLPSSKYFNNIDPQPSPVITTEIASGRFEDDIRRMRMAAHHGADHLMV
                     IRTAGQSHFDGLIEGTPQGIGGVPITRKQVRAQRKALDFIEEEVGRPINYHSYVSGVA
                     GPEVAVMFAEEGVNGAHQDPQYNVLYRNINMVRSFVDACEAKKIMAFANIAQIDGAHN
                     ANATAREAWKVMPELMVQHALNSIFSEKIGIDKNNICLSTVPPTAPPAPCLKIDLPYA
                     VALRELFSDYKMRAQMNTKYMESSTREATVTHVLNLLTSVLTRADIQSTITPDEGRNV
                     PWHIYNIEACDTAKQALVGMDGLMDMIELKDVGELRDKARELKERAVLYMEEISEVGG
                     YFESVEQGFFVDSGNYPERNGDGISRKIKGGVGEGTVYEREEDYLAPVTAHFGYNNVA
                     QYDENAIDNPSMLIDGCTFENPDKIIYIDELDDFDNVENRLKESYEYRNGTKIKPEME
                     WCADGIVMITMMLPTDKRTAEFAALEFVKKMNLQEIEVISREVMHESEGTRIEVKGRV
                     PFDIDLNNLVIPEEPKVLTDEEIRADIEEKPMKIVSATVGEDEHSVGLREIIDIKHGG
                     IEKYGIECHYLGTSVPVEKLVDAAIELNADAILASTIISHDDIHYKNMKKLHDYCVEK
                     GIRDKVMIACGGTQVTPEIAVEQGIDAGFGRNSKGIHVATFLVEKRREMSNK"
     gene            complement(57916..58290)
                     /locus_tag="KRH23_000563"
     CDS             complement(57916..58290)
                     /locus_tag="KRH23_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine aminomutase subunit alpha"
                     /protein_id="HHS5223859.1"
                     /translation="MKKREDDFEVRRKHLQELSDDELKERFWSLATQIVEPMIELGKK
                     NTTPSIERSVLLRMGFSSLEVKPILEGVMERGLIGKGAGHVVYKLAKSKNITVREAGL
                     LLVKGEYWDEVTCLFREGVESC"
     gene            complement(58368..59798)
                     /gene="ortB"
                     /locus_tag="KRH23_000564"
     CDS             complement(58368..59798)
                     /gene="ortB"
                     /locus_tag="KRH23_000564"
                     /EC_number="2.3.1.263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-oxopentanoate thiolase subunit OrtB"
                     /protein_id="HHS5223860.1"
                     /translation="MNNSTSMKDMSYQAVMGRNNEIMKNAIGLDYSSFEQEGIGFDYE
                     KMMSETGYTLQDIEAIQSQYAVGNTPLIELKNLTKLARKCAKEGKGARIFVKDEAMNA
                     SGSFKARRAATAVYHAKQMGYKGVIAATSGNYGAAVASQAAMQGLKCIIVQECYDSNG
                     VGQPEIIEKARKCEAYGAEVVQLTVGPELFYTFLVLLEETGYFNASLYSPFGIAGVET
                     LGYELAIQFREKYKKDPDIVVCTNAGGGNLTGTARGLIKAGSINTKVVGASVDLKGLH
                     MASDNQFNKKSFTTGHTGFGIPYCTWPDRSDVPRSAARPLRYMDRYVLVKQGEVFYTT
                     ELLAQLEGIERGPAGNTSLAAAFSLAQELDEDKVIVVQETEYTGAGKHICPQLTFARE
                     NGIDIKFGNPREEIAGVNLILPERPELLKCVDIDMNKIRKSFIKNCISNNHIDNIDKL
                     SNRDIEFLMEEVKSSRDFVVDVLNNL"
     gene            complement(59791..60099)
                     /gene="ortA"
                     /locus_tag="KRH23_000565"
     CDS             complement(59791..60099)
                     /gene="ortA"
                     /locus_tag="KRH23_000565"
                     /EC_number="2.3.1.263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-oxopentanoate thiolase subunit OrtA"
                     /protein_id="HHS5223861.1"
                     /translation="MDAKINDWVIIHNIVLTPEERAPQVPEDTKKVSLEMWVKGFIQS
                     DASIGDLVEVKTITGRLVKGNLLKINPYYTHDYGKCIPELLQIGIQAKEILFGGVYNE
                     "
     gene            complement(60220..61287)
                     /gene="ord"
                     /locus_tag="KRH23_000566"
     CDS             complement(60220..61287)
                     /gene="ord"
                     /locus_tag="KRH23_000566"
                     /EC_number="1.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,4-diaminopentanoate dehydrogenase"
                     /protein_id="HHS5223862.1"
                     /translation="MRKVRVGIWGFGAMGIGMANMILKKEGIEIVSVCSRSTSGKSMY
                     DVLGIERGERPEVIINKNYEEVFREKSVDVVLLATDSFTKKAFDKIIFLLNRKINVIS
                     TAEQMAYPQADDADLAKKMDEVAKENGVSILGTGINPGFVLDLLVLALSGTCEEVTSI
                     KAKRVNDLSPFGKSVMVEQGVGVTREEFIKGVEDKTIAGHVGFVESINMIADGLGWKL
                     DKIEQTKEPIMTTVDRKSKYGEALAGNVAGCRQCGYGYVNGEVLIEMEHPQQIIPEAE
                     GIKTGDYVSIKGIPNIDLQINPEIPGGVGTYAMIVNSIPLIINARPGLKTMLDIPVPR
                     AIMGDIRNQIEVELEEESKAN"
     gene            complement(61543..62916)
                     /locus_tag="KRH23_000567"
     CDS             complement(61543..62916)
                     /locus_tag="KRH23_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54 interaction domain-containing protein"
                     /protein_id="HHS5223863.1"
                     /translation="MNEILENIDEGVHFVNKDGKTIIYNNSVQKMEKMNRHDILANSF
                     FDIVNKMKINRSTLLEVLEKREVIKDNIQKYLDKNGKEITAINTTIPIDIKGEFVGAL
                     EISKNMTTIENLLNRNYKKNLVNKVSSRQKKGYEFDDILGESNLIKEAIAKSKKACKS
                     DASVFIYGETGTGKELFSQSIHYGSNRRNYPFIAQNCAALPESLFEGILFGTSKGGFT
                     GAIDRPGLFEQANKGTLLLDEINSMPIMLQAKLLRVLQEGYVRRVGGTKDIPIDVRII
                     ATTNESPKVILNEHKMRKDLYYRLNIIHIKIPPLRDRKEDIPLLCKKFISKYNKKLNK
                     KVVGISDEAIKILKNYDWQGNIRELENIIYCTMSMMEDEVQIETSMINLNDYYNLKEN
                     KESNNYSLNDLEDKTLSKIISEIEEKYIYESLEKASYNITKAASILGMNRQNLQYKIK
                     KYNIKIL"
     gene            complement(63892..64032)
                     /locus_tag="KRH23_000568"
     CDS             complement(63892..64032)
                     /locus_tag="KRH23_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5223864.1"
                     /translation="MENLMMSIITGVIASYIYDKLKSHSERPTKSGWELNIKFQKSKS
                     SK"
     gene            complement(64292..65452)
                     /locus_tag="KRH23_000569"
     CDS             complement(64292..65452)
                     /locus_tag="KRH23_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp27"
                     /protein_id="HHS5223865.1"
                     /translation="MKLSKTLLAIGMSVSLLIASCPTSNALSSINSIKGTNKYETAGL
                     IADKQNYDIAILINSENGLSDGLSASGLSGAKNAPILLTKKDTIPSETLKRLEKVKEV
                     YLIGGKNSIGASVQKILSDKKISINRISGTDRIDTSHKVAKEIGRVSTVKKVILTNAF
                     KGEPDAMSVASIAVRDKSPIVLTDGNTTSFVTDGLETYAIGGKVSMSDKLINETKATR
                     IGGVDRYDTNKQIINKFYNGSKEFYIASGTDLVYSLVGSTIAQKTPIVLVGNGSNKSI
                     LKNASKITAIGNIDDVVIKQCLNITNNVGDSNTGIVKDTNSNNTNKPSNEPSSNNPGL
                     TDKSTVYVTPNGKSYHLTKNCSTLKRSKTINKVTLKQAKSQGKIDPCNVCVK"
     gene            complement(65623..65826)
                     /locus_tag="KRH23_000570"
     CDS             complement(65623..65826)
                     /locus_tag="KRH23_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4236 domain-containing protein"
                     /protein_id="HHS5223866.1"
                     /translation="MGFNFRKSINLGGGLKLNLGKKSVGISAGVKGARVSVNSKGRKS
                     VTLSIPGTGISYTKTSTKKRKPK"
     gene            complement(65913..66947)
                     /locus_tag="KRH23_000571"
     CDS             complement(65913..66947)
                     /locus_tag="KRH23_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YHYH domain-containing protein"
                     /protein_id="HHS5223867.1"
                     /translation="MFKKKLIAVAMSITMISVGSFSYAHSGRTDSSGGHRDNKNKSGL
                     GSYHYHCGGYPAHLHNNGGCPYTGGGSSSGTTTSVNNEEKQKRSVGEKGYNQGYEDGY
                     KGNYSSSNYSGDYSDTYESKYSEGYEKGKAKLEEEEKVAKETGYNLGLTGAKSNNTYE
                     KEVLKNAYDTGYSTGYNEYKTKKIEEYKVKGIEDSNKDKEKMTFEENIDSEFIDAYNN
                     AYDEIQEQLKNDYTTQGFESAIKGERFDTSTIGNVKYANWFKEGYDNGKVKLPKAKES
                     VYNQGYNEEDFSIPDEMKSIETKLKGVYDEGLEKREEEKSRNATYGVGAGTAAVVAGV
                     VYKKKKRKKI"
     gene            complement(67469..68830)
                     /gene="rlmD"
                     /locus_tag="KRH23_000572"
     CDS             complement(67469..68830)
                     /gene="rlmD"
                     /locus_tag="KRH23_000572"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HHS5223868.1"
                     /translation="MSVKKKDVIEFEVDKMEFGGTSLSQVGDRVIHMKGGISGQKVRA
                     GVKKVRSKKAEVKMIELLENSPLETEETCKHFRECGGCTLLSVPYEKQLEIKEKQVMD
                     LFLKQDLFGFQFLGIEGSPENKYYRNKMEYTFGDEVKNGPLTLGLHKKGKHIDIQTVE
                     ECMLVDEDFSKILVSSVEFFNEKKLPYYRTMNHKGYLRHLVVRKGIHTNEIMVNIVTS
                     SQQDFDMNEFKDMLLGIDLKAELVGVLHTINDGLADAVQCDELRVLYGRDYIQEEILG
                     LKFKISPFSFFQTNTKGAEVLYSIARDFIGDYNDKVVFDLYSGTGSIGQVMAGAAKKV
                     YGIEIVEEAVVTANENAKLNGLTNCEFIAGDVAKVVKDLKDKPDLIIVDPPRPGIHKD
                     AIRDICGFGAKEIVYISCNPKSLVVDLVDFKGYGYEIKMVKCMDMFPNTPHCETVVKL
                     IRE"
     gene            complement(68857..69579)
                     /locus_tag="KRH23_000573"
     CDS             complement(68857..69579)
                     /locus_tag="KRH23_000573"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_function: GO:0140098 - catalytic activity, acting on
                     RNA [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HHS5223869.1"
                     /translation="MAKKQRIDKILSNLGYGSRSEIKKYCKQGSVVVNGSEVSNPGTQ
                     VDTENDEILFNGEEVIYREYIYLMMNKPDGYISATTDKYDPTVLDLIDLSYLAFEPFP
                     VGRLDKDTEGLLVLTNDGKLSHRVLSPKKHVPKTYYAKIDGVVTEEDVEAFLEGVVLD
                     DGYKTMPSQLNILKSDDESEIELTIHEGKFHQVKRMFESVGKKVVYLKRLSMGNLKLD
                     ESLELGEYRELTDEEVKLIEER"
     gene            complement(69579..69908)
                     /locus_tag="KRH23_000574"
     CDS             complement(69579..69908)
                     /locus_tag="KRH23_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1904 domain-containing protein"
                     /protein_id="HHS5223870.1"
                     /translation="MPQIKIRGINENDICKISEKMINDLVEAVKCPRDYFEIECIKSV
                     AIRNGKIADVYPFVEVAWFDRGQEVQDIVARIITDSIRNNLDVESMDLAFTVFEKEKY
                     YENGEHF"
     gene            70238..71164
                     /gene="fba"
                     /locus_tag="KRH23_000575"
     CDS             70238..71164
                     /gene="fba"
                     /locus_tag="KRH23_000575"
                     /EC_number="4.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004332 - fructose-bisphosphate aldolase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA];
                     GO_process: GO:0030388 - fructose 1,6-bisphosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-1,6-bisphosphate aldolase"
                     /protein_id="HHS5223871.1"
                     /translation="MALITTKEMFKKAYEGGFAIGAFNISDLEQLQGVLKAAKAKNSY
                     VMIQASMSAVKYAGPHTLVEMVKAASDEIGVDVALHLDHGPNMDAIKTCIDAGFSSVM
                     IDGSHFDFEENVRITKEAVEYAHSKGVVVEAELGVLAGTEDDVTSDVHKYTQPAEAVE
                     FVERTGVDSLAIAIGTSHGAFKFKGEAKLRFDILEEIQSKLPGFPIVLHGASAVDQNA
                     VATCNEFGGNIAGAKGVPVDMLRKASSMAVCKINMDTDLRLAMTAAIRKFLAENPKEF
                     DPRKYIGAGRDAIQAVVESKIDDVLGSANSIN"
     gene            complement(71299..72930)
                     /locus_tag="KRH23_000576"
     CDS             complement(71299..72930)
                     /locus_tag="KRH23_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54 interaction domain-containing protein"
                     /protein_id="HHS5223872.1"
                     /translation="MDNNLIGLIEHVENPAILCKESGEIIYCNHLIDSIFSFLDIKKP
                     RNINELDSNFDKTEILTDSKKKIAFRELRMTAHIYNMKDNNNENNIVYLFEKSLISDK
                     VIEDIIEHIDEVVVVFNKDGVIEKMNTVSDEILPFKRTEVLGRNITDLVRQGLVEEPI
                     ILNMLKVKKKIYRNIVYPDGKLIAYTAVPRWDSKGKLTGGVLTGRDISRVIKLESQIK
                     YSDISEDTEYISQSKIMDNIKKVVKRAAASDSSIFINGESGVGKEIIARTIYKYSSRR
                     DKPFIAINCGAIPNELLESEFFGYEEGSFTGAKKKGKKGLFEEANGGTIFLDEIGELP
                     MQMQKKLLRVIQENTITRIGGSKPIKIDVRYISATNISHEDLRNNLKFRQDLYYRLSV
                     IPVKIPPLRERKEDIVPLVNYFLKLYNEKYNREVEVSPKVIDLLEEYSWPGNIRELKN
                     IIERFVVLSAKNVIGEDEFNMLINLDMIDNETDDLSPIVVNGIMNLNDAYKIVDQIMI
                     SKAINKYGSITKAAEVIGIYPSTIHRKIKSGHIHV"
     gene            complement(73413..74450)
                     /locus_tag="KRH23_000577"
     CDS             complement(73413..74450)
                     /locus_tag="KRH23_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit
                     alpha/FixB family protein"
                     /protein_id="HHS5223873.1"
                     /translation="MNDIKDLSSYKNVWIFAEQREGKIAPVVIELLGEGRKLAKEVDA
                     ELCAILLGKDVDGLAKELITFGADKVYVADDALLEKYTTDAYTKVIKDAIDEIKPEIM
                     LFGATHIGRDLAPRIASRVGTGLTADCTKLEIDPEDKKIKQTRPAFGGNIMATIICPN
                     HRPQMSTVRPGVMDKAEKDETRTGEVIALDYKITQDDIRTTVLETVKTKKDLVSLTDA
                     NVIVSGGLGLGGPEGFEMLKKLADKLGGVVGSSRAAVDAGWIDHSHQVGQTGTTVKPN
                     LYIACGISGAIQHLAGMQSSDFIIAINKNPAAPILEIADYGVVGDLHEIVPMLIEKLD
                     SVDDLLEAIKA"
     gene            complement(74469..75254)
                     /gene="etfB"
                     /locus_tag="KRH23_000578"
     CDS             complement(74469..75254)
                     /gene="etfB"
                     /locus_tag="KRH23_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta"
                     /protein_id="HHS5223874.1"
                     /translation="MKILVCVKQVPDTNEVRINKETGTLIRDGVPSILNPDDANALEE
                     ALKIKDEHDDVTITVITMGPPQADFMLRECLAMGADDAILLSDRAFGGADTWATSNTI
                     AAGISKVGDYDIIFAGRQAIDGDTAQVGPQIAEKLDIPQVTYVQDFKIEGKDIIVQRQ
                     LEDGYELIKVSTPVLLTAVKELNTPRYMSVDKIVKAYKHDVKVWTIDDLDVNKEEVGL
                     KASPTKVFRSFTPEPRGKGEILEGKADEIASKIIIGLKQKHII"
     gene            complement(75287..76420)
                     /gene="acdB"
                     /locus_tag="KRH23_000579"
     CDS             complement(75287..76420)
                     /gene="acdB"
                     /locus_tag="KRH23_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative isocaproyl-CoA dehydrogenase AcdB"
                     /protein_id="HHS5223875.1"
                     /translation="MLYNKEQELLRKAVRDFVSKELDTLPAEMDKTGVMPKELIKKLA
                     DAKFISSNIPEEYGGGGAGYVSYAIVMEEIARRCASTATFVTAGSSLASLPILYNGTE
                     EQKQKYLKGIATGELIGAFGLTEPGAGSDAGGQQTTAELVGDHYILNGRKTFITNGPF
                     CDVAIVIAVTDRSKGLRGTSAFIVESKWDGFSTGAHEDKMGIRGTETSDLIFENVKVP
                     KENLLGKEGQGFKIAMGTLEVGRIGVAALALGIAQGALDEAVKYTKQRVQFGKPIAKF
                     QNTQFTIADMETKVCAARGLVYDAAQKRDAGMRVAQESAMAKYYASEIANEVAYKALQ
                     LHGGYGFIKDYEIERMYRDARIVSIYEGTSEVQKMVISSNVLK"
     gene            complement(76468..77595)
                     /gene="hadC"
                     /locus_tag="KRH23_000580"
     CDS             complement(76468..77595)
                     /gene="hadC"
                     /locus_tag="KRH23_000580"
                     /EC_number="4.2.1.157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(R)-2-hydroxyisocaproyl-CoA dehydratase subunit
                     beta"
                     /protein_id="HHS5223876.1"
                     /translation="MEAILSKMKEVVENPNAAVKKYKSETGKKAIGCFPVYCPEEIIH
                     AAGMLPVGIWGGQTELDLAKQYFPAFACSIMQSCLEYGLKGAYDELSGVIIPGMCDTL
                     ICLGQNWKSAVPHIKYISLVHPQNRKLEAGVKYLISEYKGVKRELEEICGYEIEEAKI
                     HESIEVYNEHRKTMRDFVEVAYKHSNTIKPSIRSLVIKSGFFMRKEEHTELVKDLIAK
                     LNAMPEEVCSGKKVLLTGILADSKDILDILEDNNISVVADDLAQETRQFRTDVPAGDD
                     ALERLARQWSNIEGCSLAYDPKKKRGSLIVDEVKKKDIDGVIFCMMKFCDPEEYDYPL
                     VRKDIEDSGIPTLYVEIDQQTQNNEQARTRIQTFAEMMSLA"
     gene            complement(77595..78821)
                     /gene="hadB"
                     /locus_tag="KRH23_000581"
     CDS             complement(77595..78821)
                     /gene="hadB"
                     /locus_tag="KRH23_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(R)-2-hydroxyisocaproyl-CoA dehydratase subunit
                     HadB"
                     /protein_id="HHS5223877.1"
                     /translation="MSEKKEARVVINDLLAEQYANAFKAKEEGRPVGWSTSVFPQELA
                     EVFDLNVLYPENQAAGVAAKKGSLELCEIAESKGYSIDLCAYARTNFGLLENGGCEAL
                     DMPAPDFLLCCNNICNQVIKWYENISRELDIPLIMIDTTFNNEDEVTQSRIDYIKAQF
                     EEAIKQLEIISGKKFDPKKFEEVMKISAENGRLWKYSMSLPADSSPSPMNGFDLFTYM
                     AVIVCARGKKETTEAFKLLIEELEDNMKTGKSSFRGEEKYRIMMEGIPCWPYIGYKMK
                     TLAKFGVNMTGSVYPHAWALQYEVNDLDGMAVAYSTMFNNVNLDRMTKYRVDSLVEGK
                     CDGAFYHMNRSCKLMSLIQYEMQRRAAEETGLPYAGFDGDQADPRAFTNAQFETRIQG
                     LVEVMEERKKLNRGEI"
     gene            complement(78836..79636)
                     /gene="hadI"
                     /locus_tag="KRH23_000582"
     CDS             complement(78836..79636)
                     /gene="hadI"
                     /locus_tag="KRH23_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyisocaproyl-CoA dehydratase activator
                     HadI"
                     /protein_id="HHS5223878.1"
                     /translation="MYTMGLDIGSTASKGVILKNGEDIVASETISSGTGTTGPSRVLE
                     KLYGKTGLAREDIKKVVVTGYGRMNYSDADKQISELSCHARGVNFIIPETRTIIDIGG
                     QDAKVLKLDNNGRLLNFLMNDKCAAGTGRFLDVMAKIIEVDVSELGSISMNSQNEVSI
                     SSTCTVFAESEVISHLSENAKIEDIVAGIHTSVAKRVSSLVKRIGVQRNVVMVGGVAR
                     NSGIVRAMAREINTEIIVPDIPQLTGALGAALYAFDEAKESQKEVKNI"
     gene            complement(79675..80874)
                     /gene="hadA"
                     /locus_tag="KRH23_000583"
     CDS             complement(79675..80874)
                     /gene="hadA"
                     /locus_tag="KRH23_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isocaprenoyl-CoA:2-hydroxyisocaproate
                     CoA-transferase HadA"
                     /protein_id="HHS5223879.1"
                     /translation="MLLEGVKVVELSSFIAAPCCAKMLGDWGAEVIKIEPIEGDGIRV
                     MGGTFKSPASDDENPMFELENGNKKGVSINVKSKEGVEILHKLLSEADIFVTNVRVQA
                     LEKMGIAYDQIKDKYPGLIFSQILGYGEKGPLKDKPGFDYTAYFARGGVSQSVMEKGT
                     SPANTAAGFGDHYAGLALAAGSLAALHKKAQTGKGERVTVSLFHTAIYGMGTMITTAQ
                     YGNEMPLSRENPNSPLMTTYKCKDGRWIQLALIQYNKWLGKFCKVINREYILEDDRYN
                     NIDSMVNHVEDLVKIVGEAMLEKTLDEWSALLEEADLPFEKIQSCEDLLDDEQAWAND
                     FLFKKTYDSGNTGVLVNTPVMFRNEGIKEYTPAPKVGQHTVEVLKSLGYDEEKINNFK
                     DSKVVRY"
     gene            81551..82549
                     /locus_tag="KRH23_000584"
     CDS             81551..82549
                     /locus_tag="KRH23_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-2-hydroxyacid dehydrogenase"
                     /protein_id="HHS5223880.1"
                     /translation="MKILVFGARDYEEPVIKKWSEEHKDVQVDIYPENMTEENVVKAK
                     GYDGISIQQTNYIDNPYIYETLKDAGVKVIASRTAGVDMIHFDLVNENGLIVTNVPSY
                     SPNAIAELAVTQAMNLLRKTPLVKKKVCEGDYRWIAELLGTEVRSITVGVIGTGKIGA
                     TSAKLFKGLGANVIAFDQYPNSDLNDILTYKDSLEDLLKEADLITLHTPLLEGTKHMI
                     NKDTLAIMKDGAYIVNTGRGGLINTGDLIEALESGKIRAAALDTFETEGLFLNKKMNP
                     GELTDPEINKLLSMEQVIFTHHLGFFTSTAIENIVYSSLSSAVEVIKTGTATNRVN"
     gene            82911..83438
                     /locus_tag="KRH23_000585"
     CDS             82911..83438
                     /locus_tag="KRH23_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04002 family protein"
                     /protein_id="HHS5223881.1"
                     /translation="MEKMNKVTSKKTTYIVTSALFASIICLTIAYILHIPVGGNNGYV
                     HIGDAFIYLAATILPTNYAIAASAIGAGLADLSTGAAIWVIPTIIIKPILVLFFTSKS
                     DKIINKRNIVASVVAGIVGLVLYMFAEGIIIGSFTSAFVMSLLGLLQPIGSFIVFIIL
                     GMALDKLDFKKRYFN"
     gene            83465..84061
                     /locus_tag="KRH23_000586"
     CDS             83465..84061
                     /locus_tag="KRH23_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0046500 - S-adenosylmethionine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04100 family radical SAM protein"
                     /protein_id="HHS5223882.1"
                     /translation="MNILYTIENSIYVNITNTCPCSCVFCIRNEKDEVANSGSLWLEH
                     EPSVDEVKEAFNKYNLDDYDEIVFCGYGEPLMRINELIEVAKFIKEKSSIKIRINTNG
                     LSDLIHNKKTAILLKNVIDAVSISLNAPNKEAYNRVTQPKFGEKSFDYMLDFAKDCKK
                     YIKEVAFSVVDEISPEEIEESKQLAKKLDIPLRVRHKN"
     gene            complement(84126..85709)
                     /gene="asnB"
                     /locus_tag="KRH23_000587"
     CDS             complement(84126..85709)
                     /gene="asnB"
                     /locus_tag="KRH23_000587"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: protein motif:HMM:TIGR01536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HHS5223883.1"
                     /translation="MINLEEKYLTRKDTYMIKILEYNGHIRNWKVLCEELGIDSSLCR
                     DERERAILVEAYKTWGYDMANHMHGMFAFALWDTVEKKLFCLRDQFGVKPFYYYETEN
                     GKLLYGSSIRKIMEQPGFVKELNEDMLQIYMSFTYVAGENTFFRGVKKLMPGHYLVYQ
                     NKTVCIGRYWKPEFHPDHSKSIEEWTDEIHTTLQKIMPEVKSENETAELFLSGGVDSS
                     YILAMSDIEKTGSCGYEEERFDESKLAQQTANILGCKNSRYIITPEEYFASVPYVMYH
                     MEQPTGDASAIVFAIGCKAAAENTNICYSGEGADEFFGGYNIYHKAECYGENLKTFYI
                     GNTNIMNEGEKRKILKKYNPDVIPIEVVKGIYEETEELDTLTNMSNVDIQIWLEGDIY
                     FNIDKMSTAVGLEVRMPLTDTRIFDIASRIPSEYKVKGKENKIAFRTAASKTLPEEIA
                     FRNKLGFIVPIRIWMADDQYNKDIRDKFNSEIADKFFNIDEINEIFNDYISGNSDNWR
                     KIWMIYTFLVWYEIYFVKC"
     gene            complement(86274..87110)
                     /locus_tag="KRH23_000588"
     CDS             complement(86274..87110)
                     /locus_tag="KRH23_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HHS5223884.1"
                     /translation="MNYIIKKVLNSSVVLVHDTKDNEFILLGKGIGYGKKTGEYICGS
                     NDNQMFVPVENTKSKQFLELMDDIPVDILKITQEIIVEAEKLLNSSFNKNLYLILADH
                     FNFAIERMRKGIKITNRVFWEIKNYYPNEFKVGMVAIYMVEERLGIQLPEEEAANIAF
                     HFANAMASDGNSYDTIKYAKVIGEIINIFVFSLNRTLDKKSMHYMRFITHIKFFVERF
                     FSDSMLSSGDDLLFNQMKRSNPKEMLIALKVRDFLEKKYGKKLTNEEIAFLVVHIARV
                     KQ"
     gene            complement(87134..88600)
                     /locus_tag="KRH23_000589"
     CDS             complement(87134..88600)
                     /locus_tag="KRH23_000589"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HHS5223885.1"
                     /translation="MRKFPEGFLWGGATAANQFEGGWNLGGKGWSVSDVAKAHFDADV
                     KDYKSNNEITTKDIEEGLAHPEDEVNYPKRHGSDFYHHYKEDIALMVEMGFKTYRMSI
                     AWSRIFPNGDDKEPNEEGLQFYDDVFDELISYGIEPLVTMSHYEPPLNIVLNYDGWYS
                     RQVINMFVRYVETICERYKNKVKYWLTFNEVDSMIRHPYTTGGLVRDRFKDKNFEEVI
                     FQAMHHQFVASALATKICHEIIPNSKVGCMLTKLTYYPYTCRPEDVLATQQKMRSIYA
                     YSDTQVFGEYPVYLLSYFKNNNIQIVKEEHDDEIMKKYPVDFISFSYYMSSCEAADTT
                     GLDITPGNTLLAVKNPYLEMSEWGWQIDSIGLRISLIELYDRYRKPLFIVENGLGAKD
                     ILTEDKKVHDQYRINYLKEHFKCMLDAIIEDGVELWGYTSWGCIDLVSESTKQMSKRY
                     GYIYVDADDYGKGTYNRYKKDSFYWYKKVIENNSIDFK"
     gene            complement(88603..90465)
                     /locus_tag="KRH23_000590"
     CDS             complement(88603..90465)
                     /locus_tag="KRH23_000590"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HHS5223886.1"
                     /translation="MNYKKTAIDIIEQVGGSKNILALEHCSTRLRFKLIDRSKVNQDA
                     LKKVQGVMSIVNGAQFQVVIGNSVVDVYDEILKVCPLDTNDSTVKTEEKINLGKRFIE
                     FIINIFQPLIFAIAGAGILKSLLMLLAMFNILKSDSTIYTLLVAISDATFYFLPLMVA
                     VTTANVLKCNRLVAIAAVGYLLLPATTTALSEGVELFGFTIPNIAYNAQVFPAILCVS
                     FLATMEKIFNKYSPKPIRTFFVPMMSLAITVPITLTILGPLGYNVGTIFTTIILFLYN
                     KMGFLVVGLLAAFLPFMVATGMHKALIPYSINTIGKLGYEALYMTSSLAHNISESGAC
                     FAVALRTKDETLKQTALSAGISALMGITEPALYGITLQHKRAMLGVVFSSAISGTFLG
                     LFAVKGFVIVGPGFASMSMFIDPNNGNNLIFASIGFVIAILGSFIITLIIWKEDTNTV
                     ESSIGDVVEEELEEEKEVNILVTPVEGKVIDLSKVNDELFASKTLGDGVAIIPTNGNL
                     YAPCDSEVVMLFETKHAIGLRTKNGAEILIHIGINTVSMNGDGFKTFVKTGDNVKEGD
                     LLIQFDLDKISHANLDSTVMIVNNNGADYAYKVLNQSYGNVKKGSILFDVKGGI"
     gene            complement(90712..91575)
                     /locus_tag="KRH23_000591"
     CDS             complement(90712..91575)
                     /locus_tag="KRH23_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015144 - carbohydrate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0034219 - carbohydrate transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GRP family sugar transporter"
                     /protein_id="HHS5223887.1"
                     /translation="MILSYFALLIRVVLLAFERVVVRLLGDEEGDIYKNIASSFLFFF
                     IGGVCLLPFSIMDRVSDWSFLIPCYISSLVYSIGSVAYVTSLATGEVSLVTPINSLNS
                     LFLLLLSVIFLGEGLSLAKVAGIIIMIGGVFILKKVSSFLKNVSVIFNNLPCRLMFLY
                     IFLQSVGRVLDKAFFVQVSPILYSTILYFFVGLNLFIFLAFKKKQKIICEIFTNKKGL
                     SILSGAINGYSYLALLIALNNLELSIAEPFSQVSMIITLILAHFIFKENIKEKIPGSI
                     LILIGGWLLLL"
     gene            complement(91630..92562)
                     /locus_tag="KRH23_000592"
     CDS             complement(91630..92562)
                     /locus_tag="KRH23_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacyl-tRNA deacylase"
                     /protein_id="HHS5223888.1"
                     /translation="MNNKKAVFFFCSDLKKDPVASNVIKCCEEIMDLNQTDIVIDDNF
                     VLEFKDKNNNLFHFVKTKDVISHNYKYYLPILNRHFRDYDFAGVVNWHEGENAPEHIL
                     TAHTIGDVPTGEFGNSNPRYFKNLINAIEDIKNENLLDEFTTLTEATHWSGTTYGEES
                     KLITEYSVPMLDIEIGSSSDSFNNSIAIQVLAKSLIRVFDCDEPLKTLLCVGGVHFEK
                     SFSDIIKNKEYNISIGHVLPNQWIVSGMYDDESGFEKLEKCINSIEGGIDCIVFHDKL
                     KGTYKEQCRKLGEKLNVPVFKHKILKNPKDLPIW"
     gene            complement(92648..93199)
                     /locus_tag="KRH23_000593"
     CDS             complement(92648..93199)
                     /locus_tag="KRH23_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHS5223889.1"
                     /translation="MQSLNEIIAENLKKIRKEKHLSLDKIAQLSGVSKSMLSQIEKCE
                     VNPTISTLKKITNGLKISFTSLMERQESDIELIQKSDIDHFIEDNGKYISYPIFPFDS
                     KRRFEIFMIEIEEGGNLDSNAELPGTQEFITVFSGEVTIKINGEDYIVSSGNSIRFKA
                     DVSHIYRNSGKGIAKMSMVVYYI"
     gene            complement(93428..93919)
                     /locus_tag="KRH23_000594"
     CDS             complement(93428..93919)
                     /locus_tag="KRH23_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5223890.1"
                     /translation="MIDLKIENRKGKIHVKSSEIKDILELRPDFEYVQDISNTINQEN
                     ILVFDCQLTGNSFDMDDLDIEEILEELGEEIDESYFSVLFEDVRAYLKDATDEIEADL
                     QDNYLFDNLRCYFDIYNINQEFTDFKFVFLVSFKDIKISSLANLAKIVSKRQLIGASK
                     FYS"
     gene            complement(93947..94507)
                     /locus_tag="KRH23_000595"
     CDS             complement(93947..94507)
                     /locus_tag="KRH23_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008253 - 5'-nucleotidase activity
                     [Evidence IEA];
                     GO_process: GO:0009264 - deoxyribonucleotide catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5' nucleotidase, NT5C type"
                     /protein_id="HHS5223891.1"
                     /translation="MNKLNICIDIDGTITSPYHFLPYLNDIFNKNITEAECITHNWEE
                     LYGSGIRDVYAEFNNKYIHSYDEAKIVEGATEVISTLSKGHNLSFVTARHECLTDVTK
                     NWLSRQGFSDIDVYLLGSDYKVEKARELSCDIFIEDNPLNSVQLADDGVKVILLDTNY
                     NKDVKHQNIVRVSNWIDIEKIIKQGI"
     gene            complement(94659..95816)
                     /locus_tag="KRH23_000596"
     CDS             complement(94659..95816)
                     /locus_tag="KRH23_000596"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HHS5223892.1"
                     /translation="MNKQSIGKLNMFFMGITQRNLDNRDFFIELEVIFKSGRKEFKGI
                     AIEEDNKYKFNFKGKSDLYTFNELLKNISKEAENYDGLVFKYVERGTIVVIEGDNKKV
                     NVKYLDNKEEVPKIDEFTASQIKNRDYYVKVGQANALLKEIGVLTKDGKIKNDKIRKY
                     NQIDHFVELIDSILKEIKDKDCITILDCACGKSYLSFVLNFYIKEVLKKNCYFIGIDY
                     SDVVIEASKNMAKNLGYKNMSFIKEDLTNYTPNRDVDLVISLHACDTATDMAIGLGIR
                     AKSEAIVVVPCCHKELLGQYRYEAMEPILKHGVFKARFADLITDGLRTLLLEGNGYDT
                     SVVEYISPLDTPKNLMIRAIKTKTNNDKALKEYKELKSQFGVEPTLEKLIY"
     gene            complement(95853..96794)
                     /locus_tag="KRH23_000597"
     CDS             complement(95853..96794)
                     /locus_tag="KRH23_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5223893.1"
                     /translation="MRWILVFIFLYLIPLVVIFRNYKNFKRSCIYSSIYVVLATTIMI
                     SNIYMSGLNKIKESMYYHNYISDETYDEKYVSNFKEKESTDLKQDNKKNEEISNNKNL
                     NNKQDRNIQNKESNEEGSNDIKEKNNSDSNVSVNNKSEKQEDNTKENNKYTSKEKNSE
                     DIKKIDMESIGIFKKEIYNIERAALVPMRECIPYTKDIAKNITKLSSIKKDVTNARNK
                     CKEVVKEYENMQIPELSKEKYTETLSNARDDVKKAYELREKSMESALKLINTKSPKYI
                     GKITEYLDLSDKQIESFKNRLNDLKEEINNSETNNIN"
     gene            complement(96881..97573)
                     /locus_tag="KRH23_000598"
     CDS             complement(96881..97573)
                     /locus_tag="KRH23_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HHS5223894.1"
                     /translation="MSLYAIGDLHFSTSVNKPMNIFGSNWDGHEKKIIDNWKEVVKEE
                     DMVLVLGDTSWGINLSEAKKDLDIISKLPGQKILIKGNHDYWWTTVTSLNKLYEDMRF
                     IQTNFYEYKDYAICGGRGWICPNDVKFDETDEKVYKREEHRLRLSLESARKSGHSKII
                     VITHYPPTNDKLEESLFTKLFEEYNVEKVIYGHLHGKESFKMGLKGIRNGVEYTLASC
                     DYTEFNLIKVHD"
     gene            complement(97681..98493)
                     /locus_tag="KRH23_000599"
     CDS             complement(97681..98493)
                     /locus_tag="KRH23_000599"
                     /EC_number="2.7.6.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008728 - GTP diphosphokinase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0015969 - guanosine tetraphosphate
                     metabolic process [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase"
                     /protein_id="HHS5223895.1"
                     /translation="MEYEKWNEILAPYEHAVEELKIKFKNIRKEYLAKGEYSPIEFVT
                     GRTKKISSIISKLKRINAKDIETEIDDIAGIRIMCQFVEDIYAIVDLIKVRNDMTIIG
                     EKDYITNYKDSGYRSYHVIIKYPINSIAGSKEIICEIQIRTLAMNFWATIEHSLKYKY
                     DHYIPETLAERLRRASDAAFLLDQEMSEIREDIMKAQAMYQMKSIAIRDTLNRIQELY
                     DLGDTHKAMQYQRKLDRTETDKNITEILELKQEIDILLEQYKDTKVDDKVVQ"
     gene            complement(98544..99455)
                     /locus_tag="KRH23_000600"
     CDS             complement(98544..99455)
                     /locus_tag="KRH23_000600"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HHS5223896.1"
                     /translation="MNLTKVKGNTFFIKGGTNTGIYVFEDNTALMIDPGLCGSRPRRV
                     NKVLDENNIQVRYIINTHGHDDHYGACNQFKEYYKDVCIMSSEYDKLYIENPELFSKY
                     IVGGKSNVFMDNILKNKMLDDIKIDKSIEAGKIELNNEMFDIIEFQGHTPGSIAVLTK
                     DNVIFVGDLLIGDEILSKYDFLFLYDIQEQINSLEKLKNIDFEYLVLGHGKQVISKED
                     SYKLIEKHLNALKKYLYQIRELLVEPKSLEILLKNIINNNNLSNNYKEYHFFKSSLVS
                     VISYLVDLEEIGYILENGELLYYTKTK"
     gene            complement(99514..100245)
                     /locus_tag="KRH23_000601"
     CDS             complement(99514..100245)
                     /locus_tag="KRH23_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YkgJ family cysteine cluster protein"
                     /protein_id="HHS5223897.1"
                     /translation="MTSIKNKDILNCIDYSIKNKLFDKLNDVYKSLPVGNCSGCGNCC
                     MESVGINLIEFLNIFCYLEDRVDLKKSCISKILDYYFEEYTRKNPCPFKDTNNRCLIY
                     EVRPLNCRMFGHWKKEDYNKNLDNVIEKNNNYRELMKKQYGFEINDEVVNYRIDYCDR
                     FIPNKDYLSKSKRLSFFDELMILDSNIYSSGNIDIDFRDRGIVEYFIESLLYRNLAYN
                     VKIRISKEYKIRKRTIDRIKRIVLV"
     gene            100334..100585
                     /locus_tag="KRH23_000602"
     CDS             100334..100585
                     /locus_tag="KRH23_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5223898.1"
                     /translation="MNRYTKIINMMGSYYTKDFEKEKKNVIKVREVKEDTVRKFFLQG
                     DCEVLVVFEDTGKEILIDDFSPEEDIKKYLGAKFINKKR"
     gene            100818..101237
                     /locus_tag="KRH23_000603"
     CDS             100818..101237
                     /locus_tag="KRH23_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5223899.1"
                     /translation="MQIYFRVKAVGKRKPMLELTPFDVSDNINCLKEAISEIVSKNVL
                     EYNEKIPEKSIINFLTNEEIESQADIGKVGFGSIYNENKQSVEKAIEVALQAFEDGIY
                     KVLINEDVIEKLDSSINLKSGDIFTFIRLTLLAGRMF"
     gene            101262..106319
                     /locus_tag="KRH23_000604"
     CDS             101262..106319
                     /locus_tag="KRH23_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4132 domain-containing protein"
                     /protein_id="HHS5223900.1"
                     /translation="MLERTRVEKNPKIIENFKNNFTKSSSKQYYDLAKSLWDCIENSS
                     YYYREPEDKFLNMIKKYYNCHYYEIKNMDELLSGPLKNALELIFTSEQVEELCQLIKR
                     KMDYTYSGGYYRKGYRSNKLVDYFRGIIRFISNYVDLIYYDFSVIDYLTLPNKVLYYD
                     SIMSDKIALEIDKGNQKVISALEEVIFGENQTALLTRQMIIGIMKSHSDKCYEMLSKL
                     LLAAKQQEGLRQQIVESLDEGTISASIYMLKTILDNNLERFSSVIRALDTWTGLGFSD
                     QKPGIIRKCLELSYKSLTDEKFRIESINSNDNLEIYFALWATATYNIYDSFSLIENLL
                     SCQEKYKKLVALYFLSHTESTYFKHSIASKNIKGDDLEILAWVITNFYVESSVGYYYS
                     WQNRETNFDLSNTPIDKDFDARKEQFESLKHTLEILNSKTKSFSGSVFPWTWIEISSH
                     EILKCMMTLTAYDMNAQFIDVLMENCHLMSSDLRASLIVNFVNEPKTDRQREFLLECL
                     SDKSVSNRETVLSLLRKLELTDVELDKITNLLSLKTSSIRQTVIKILLEQDDSNLENI
                     ASSLIKSSNSQKCLGGLEIVNLLKDNTARQELYNKLILLIEDIDKSKKNTSQVQILID
                     NLLGKAKNDYCKENGFGIYNPENKVQIPEQFDFKDDSNSSSKLNKIISNISLSTREDS
                     VSVATKKEAKKILDTDINKIIKVYEKFDELITENADYEYEVERWSGNVDKVLLGYSTY
                     NLTPIKYKVSNDTLDNYPLAELWRETSKKLDLDYKLILDILFYSISICGYNETEKSWF
                     SSIYSNVLDSKKQNKIYTKLEKLKFNGLTRKLLRVLLNEFDHKEIFNYCLEIYYKLRN
                     LLTIEQCKKQRVEFTKNYYRQNEYCPALNAPILNYWLDKAHSFIYDDISFTKFFYTTF
                     SNYQLLEYKFPFYTSINVFARAHELGLMTEEQVNREMISGYNASNIIRTLTNPRWAGD
                     TLEKYPWLKDNLKTVTNRIIEIESRRGDMPTEVSHLANNIQYFEGINYFVNILVALGK
                     ETFQRGYSYGSNYSKKDVLSSLLKNCYPTKEDDSKKLKSLLKNTDITELRLIESAMYA
                     PQWVNIIEKYLNWKGLKSTIWYFHAHINEGFSAQKESEVALFSPISPRSFIDGAFDVD
                     WFLDSYKTIGEERFNILYKSAKYITSGGNSHRRAQLYADATLGKLDKDMLMKEIETNR
                     NQDKLRSFSLLPMKKGDLKEATFRYEFIQKFAKESKQFGAQRRESESKACTIALENLA
                     RSAGFGDVNRMMWALETEKLNEVAHLFKPKDIDGTSIWIDVDENGKASTKVQKGNKSL
                     KSIPKAIAKHPYVLELKSVQKDLKSQYSRAKQSLEQAMKNEIVFTVKEIANIYKNPVI
                     CPLIKNLVWVCDDNIGYVYNDKSKFFICNIEGETYKLTAKNKLKLAHPVHLFESGKWS
                     EFQHDLFSKQIVQPFKQVFREYYRINSDELSEKTISRRYAGHQIQPKKTVALLRNQLW
                     TVDYEEGLQKVFYKENIVAKMFALADWFSPADIEPPTIETVEFFDRKTYKSLELASIP
                     PILFSEVMRDIDLVVSVAHAGGVDPETSHSTVEMRIAIAKELLLLLKINNVNFEGSHA
                     LIAGNLGEYSVHMGSGIVHKKGMGALNILPIHSQSRGKIFLPFADEDPKTAEIMSKIL
                     LLAEDSKIKDPSILSNL"
     gene            106461..106802
                     /locus_tag="KRH23_000605"
     CDS             106461..106802
                     /locus_tag="KRH23_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5223901.1"
                     /translation="MLLILGNLNLNLDFDYRIIREENEDVDIFIDINYRSLDIDTDGS
                     NLFNSRIQFPFVRALILRLNKNNQCMTIHLLRDIDLFSAFANFEVDYTDSIINIKNQN
                     EKVILNKSIKK"
     gene            complement(107162..109804)
                     /gene="adhE"
                     /locus_tag="KRH23_000606"
                     /gene_synonym="adhC"
     CDS             complement(107162..109804)
                     /gene="adhE"
                     /locus_tag="KRH23_000606"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004022 - alcohol dehydrogenase (NAD+)
                     activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006066 - alcohol metabolic process
                     [Evidence IEA];
                     GO_process: GO:0015976 - carbon utilization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HHS5223902.1"
                     /translation="MEKKEKVVEKSNVEVCSPEIVNSVETLRMRLEEIRLAQKEFATF
                     TQEQVDKIFLAASTAANQQRIPLAKMAVEETGMGIVEDKVIKNHFASEYIYNAYKDTK
                     TCGVIEKDEAFGFTRIAEPVGVLSAVIPTTNPTSTAIFKSLIALKTRNGIIFSPHPRA
                     KNCTIEAARVVHDAAVKAGAPKGLIGWVDVPSIELTNVVMAEADLILATGGPGMVKSA
                     YSSGKPAVGVGPGNVPAIIDESADIKMAVSSILVSKSFDNGMICASEQAVIVPEKIYE
                     EVKKEFKYRGAHFLNKEETEKVGKVVIIDGSLNARIVGQPAHVIAKMADVEVPKTARI
                     IIGEVESVELNEPFAHEKLSPVLAMYKSKSFEDAVAKAEKLVADGGYGHTSSLYADSI
                     NHPERVEKFVNAMKTCRVLVNTPSSQGGIGDLYNFKLAPSLTLGCGSWGGNSVSENVG
                     VKHLLNIKTVAERRENMLWFRAPEKVYFKKGCLGVAAREFKDVMDKKKAFIVTDSFLY
                     NNGYTKKLTDLLDEMGIKHTTFFDVAPDPTLACAREGAKAMADFQPDLIIAVGGGSAM
                     DAGKIMWVMYEHPEVDFQDLAMRFMDIRKRVYVFPKMGEKAYFAAIPTSAGTGSEVTP
                     FAVITDQDSGVKYPLADYELMPNMAIIDADMMMEMPPRLTAASGVDALTHALEAYVSM
                     LRTEPADGLALQAGKIIFEYLPRAYKNGKNDKEAREKMAMASTMAGMSFANAFLGICH
                     SLAHKLGAFHHVQHGVANALLINEVIKFNCAEAPNKMGAFSQYRYPDCIQRYAEFASF
                     AGIKGSTDQEKVDNLIKAIDELKAKVGLPKTIKEAGVEESKFLERLDAMVEQAFDDQC
                     TGANPRYPLMSELKEIYLKVYYGK"
BASE COUNT        36979 a        18779 c        13046 g        41524 t
ORIGIN      
        1 tttaaaatat taaatactac atatagctta cataagttta aaatttaatc tattataaaa
       61 ttaccctaat tgccaaactt tttaatataa attttccaac atcctacaaa tataatcaat
      121 agatatagaa tcctaactta caccaatata tatttattta aaatagtcct aaaatacctg
      181 taatagctcc cactactatc agtataaaca ttatttttat tggagaaaga ccttttttta
      241 aagcaaagag tactaataaa gtaagtacca aaggaattaa tccaggaaat atcttatcaa
      301 gtaaatccgt ttgaagacta aatttaaaat caccactagt ataacttatc ggtgtagata
      361 aattaataaa cctacctaca agtcccccca tgactaaggt acctagtata gaagcccctt
      421 ctataacctt atttactatt ccaccttgaa gtatactttc aacagctttt ttcccatact
      481 tatatccatt tgtccacatt ccaaaagaaa ttgaagtcat tattatatat tgagctatta
      541 caaataatat aggtcctgca attgatgctc ctccctcagt taaaccaata caaacagcca
      601 acactatagg agttataact ccttgagtta aagtatcgcc aattcccgct agtggaccca
      661 tcaagcctgt tttgatagca ttcataccat ctccacttat ttcatctgct ccattagctt
      721 tttcttcttc catagctatt gttattccat gtataacaca tccacatata ggttctgtgt
      781 taaaaaatgc tagatgagtc tccacttctt gttttaactc ttccttatct ggatataatt
      841 ttttaagtac tggcaacatt gaatgtgaaa aagctgttga ttgcaatctt tcataattgt
      901 aattagattg tgcaaagaaa aaccatctta accatgattt tattacatct ttcttgctta
      961 acgttttctt agatacttca ttttttatat ctgacataat attttccccc tcacatgtat
     1021 ttaagatgta gcactatctt ttccgtactt aattgaagta attgtaagag caagtattac
     1081 tccaataaca gatattacta ttatatctac tttaaaataa acagccatta gtattcctaa
     1141 tatgaaaaag ggcatagtaa acttgtttcc aatcaatttt aaattcatag caatcccaag
     1201 tgctggcaac atagccccaa ttacattaaa tacatgtaac acattatcat tcattacttc
     1261 caacatacca tctatcgcat ttggaccaaa ataaacaact aataatgctg gtataaaact
     1321 cattgcaaat aacagtatct gtggtggtac tatatttata aatgctactc tatcaacatt
     1381 ccctttttga acctctctat cagcccaatg tgcaaaaaaa gaatttactg tcatctttcc
     1441 aatccaaagt acagttgcaa cagttcccaa tggtacagct attgccattg cagtacttac
     1501 atctagctta gatgctatag ctaaagcagt acctacatat cctgcaaaag ctgggtcccc
     1561 catctgagct ccccctgctg atataaaacc tagatatatc atatttatac ctgctcctat
     1621 aattgctcct tgaacagggt ctcctaatat aattcctgtt acaaatccag ccaatagagg
     1681 tctattccat gtaaaaaatc caacataagt caaccacgga ctccaagaaa gataataaaa
     1741 aattgctatt aatactgctt gaattagtga aatgtgcata ttcttcctcc ctattttctt
     1801 ttaaagattt acaagatagt cttctttata ataatgttcc tacatcaatt ttctttgcat
     1861 ctggtactat ttgtataaag catttaacat cttttgatat tagctctcta aatatttctt
     1921 tttcttcatc tgacacagat atatttttat aaaaactttt tctaccaagc cctgctccca
     1981 tacctccaac attcaattcc tttaaatcta ccccactatt tactaaacct aagacagttt
     2041 tagggtattt gaccaatact attaaatttt catctccatt atgtgatttt aagacttcag
     2101 cacctgattc tacatcatgt acttcaacct taacagttga tggagctgcc atttgtaaaa
     2161 cttgaactat aaatgggtcc tttactacta aatcatccac gattactatc ctttttgccg
     2221 atgtaatctt acaccaagta gtaataactt gcccatgtat taatctatca tcaattcttg
     2281 ttaatgctat attactcata attattcctc cagattttta atttatttta caactttaaa
     2341 acagttttaa catctttgat tcctgatatc ccaacttcct cacataaatt tttcaagtct
     2401 tttaacttca tagtatctct gtttaaaaat aactctaaaa gcataggtaa atttacacct
     2461 gtcaaacatt ctaactcaca taccttagca aatttattta ttataatagc agatgtatta
     2521 aatggagttc cgccataaaa atcaagcaat actaaaaccc cttcatcctt atatttctca
     2581 attccatctt ctaactttct actaaactca tctatgctgt caccatggtt taatcctaaa
     2641 gtttctacat tttcctgttt gcctactatt aattcagcac tttctaacat tgctttagcc
     2701 atatttccat gtgtggctat aattattcct gccatatgaa tcataccttt cttaaccttt
     2761 tttatatgga ttattattta gtactctaat ctaattatct atattaatca ttatcttacc
     2821 aaagaaaata tcccttttgt atactttttc aaaataagct ggtacttctt ctaaatttat
     2881 tctatgtgtt actaattttt caacattcat atcacccttt tgcatatgat acaatccagc
     2941 actccattct tttcctggga atggaaagga gtttccaaac caagttccct ttacagttaa
     3001 ttcacttctt actatctttt caaattgctc tctagtcaaa gctacatccc catatggtac
     3061 acctgcatac aatactgtac ctcccttttt agctagcaac agtacttgac cacatgtcag
     3121 tggagtacca gccgattcaa taacaatatc tgctccatat ccatcaatta acctttttat
     3181 ttcttctaca atattctttt cttttgcatt tatacaaata tctgccccta actcttttgc
     3241 caagtctaac ttctcatcaa atacatccac agctattact tttgtagaac caaatatttt
     3301 tgcccattgt attgaaaata atcctattgg acctgtacca agtactacaa cagtatctcc
     3361 aactttagct tctgacctaa aaagaccatg tcctgctata catactggtt ctagtgcagc
     3421 ggcagtctca taacttatct catctggtat ttttattaaa tttctctctt tcacctttgt
     3481 atactctgca aaacaacctc caagttcttt atttcctatt attgctacat tattacatct
     3541 tgaatacaag ccttttttac attcatcaca ttcaaaacat ggcatagctg gacaaacagc
     3601 aactctatct cctattttaa aactccttac ttctttacca acctgtgcca cttctccaga
     3661 aaattcatgc cctaaaattt ctccaaccat atgtggacct gtctttgaat attttgatat
     3721 atcagaacca catattccag ctacttttac tttaattatt acatcatctt tttctaatat
     3781 ttttggtaca tccacatcct ccactcttgt gtctcttata ccatagaatc taactgactt
     3841 cactattaac cacccctact ttttatttga gaatatatac ttattgttta tatgttaaat
     3901 atctaaagca actttcatgc caatatatgt aagcattgta ttcatgcatt ttataaaatt
     3961 atcattaaat gtgtgtcaaa gtgtgtcaaa agtttcttat attaaaactt atgtgtgtca
     4021 atataaacaa cactaacatt ttatattagt tctcttatta taagttttat aaaatgtact
     4081 ttttttgtta tttttataaa attgttcgga aatttccctt ctatttgtga tataatatta
     4141 aatataaggt atcaatataa attttcatgc gaatatcaga acttttttga cactaatgcc
     4201 ttattcaata taataattta actttttgga ggttgtttat gaaaaaagtg tatcaaggaa
     4261 agactaaaga tgtttttgaa ttagataatg gaaattactt acttaaattt aaagacgatg
     4321 tgactggtaa agatggagta tttgacccag gcgaaaatag tgtaggtcta agtatagatg
     4381 gaattggtag agctaattta gagacatctg ttaagttctt tgaaattcta aacaatgctg
     4441 gaattaaaac tcattatgta agtgctaatt tagaagaagc aactatggaa gttctaccag
     4501 caaaagtttt tggtaatgga ttagaagtta tttgtcgtta tagagctgtt ggtagtttct
     4561 tacgtcgtta tggttcatgt gttgaagaag gtgctaaact agattgttac gtagaagcaa
     4621 ctttaaaaga tgatgaccgt tgtgaccctc ttataacatc tgaaggttta gaagctttaa
     4681 acattatgac tcaagctcaa tttgattcaa tgaaaagcat gactcaaaaa atttctaaca
     4741 tagttcgtga tactatagct gaaaaagatc ttgagcttta tgatattaaa tttgaatttg
     4801 gattctacaa tgatgaagta atcttaatag atgaaatagc atctggaaat atgcgtgttt
     4861 ataaagatgg tgtaatagtt gaccctatgg atttaactgc tcttttatta gataaatagt
     4921 atatacatat aatttacaaa tataataaac ttataaataa gataagctat gaagtaaaga
     4981 ctttttaaat gttgattatt tttaaacatt ttctcgcctt taatttcata gcttatttaa
     5041 attaatatac tctaattagt agataatagc tttaacccta caattcccac cacaataaaa
     5101 cctatacatg caattcttga tatactaata ggctcattta aaatagccat gcctacaata
     5161 gctgtaccga cggtaccaat tccagtccat attgcatatg aagttccaag tggaagatgt
     5221 tttagtgcta atgacaaaaa ataaaaactt acaatcattc caacaacagt aagtatactt
     5281 ggagttaatt tagaaaatcc atgtgaattt tttagttgaa aagcccaaaa cacttcaaac
     5341 aaacctgcaa caaacaaaaa taaccatttc ataaattcat ccctcttttc aaatatgtct
     5401 cttatttttc caataaaata acctgagaaa tattataaaa tatctcccag gtttttgtcc
     5461 ttccgtgttc acaacaaaaa ctatgttgtg ggttttatct cggaccagac caatcattaa
     5521 taattgcgga accctataaa actctattaa ttattctatt ttatctataa taatactatc
     5581 aacatatata aaaaaagtca atatatgggt tccatctata ataaaaataa cttttatata
     5641 ccttttaata ttcttattca cttctctcca tacccattta ggtcaatcta agaatatcta
     5701 atttttattt aatatgttat aataacataa aaatattgaa aggagtaatt tctatgaatt
     5761 tctataaaat tgcagtatgt cagatgatta ctacagaaaa taaaattgaa aatatcaatc
     5821 atgctgtaga tatggtaaca gaagctgcca tcaatggagc taaaattgta gttttgccag
     5881 aaatgtttaa ctgcccatat gaaaataaat attttcctaa atttgctgaa gaatatccag
     5941 gtgaaacaac aacgatatta agtaaattag ctgagaaaca tggaatttat ctagtttctg
     6001 gtagtattcc tgagttagaa gatggaaaaa tctataatac ttgctatgta tttgataaaa
     6061 atggagctct aattggaaaa catcgtaaaa tgcacttatt tgacattgaa gttacaggaa
     6121 aagttagttt taaagaatca gatactctta cagctggaaa tgatgtcact gtaatagata
     6181 ccgaatatgg aaaagttggt atagctattt gctatgatat tcgtttccct gagttatcac
     6241 gtttaatggc tcttaaaggt gctgaaatcg ttatcttacc tgctgcattt aatatgacta
     6301 ctggtcccgc ccattgggag ttatctataa gaatgcgtgc tttagataat cagatattct
     6361 atgttggtgc tgcacctgct agaaatatga atgcttctta tatagctttt ggaaattcaa
     6421 gaatttcaga cccttgggga agaataattg ctcaagctga tgaaaaagaa tgtattattt
     6481 atgctgacat tgatagagat ttaattcctg acataagaca acagttacca cttcttaagc
     6541 acagaagaac tgatttatat gaacttaata ctttgaaata aaacagaaca taaccccata
     6601 aatcgtaaat taagtgttaa aaaaatttat ggggttctca ttaatttgat ttaaaattaa
     6661 tttcataaaa ataatgctaa tattaattta attaaataat actaataatt actaatgatt
     6721 atgctaatta tcatcattta ctaatttaat cactattagt tatttctttt attaaatatc
     6781 tttacttttt tacttattat gtcttctagc tttacatttg gattatggta tttctttcta
     6841 tttttagtca catctttcta ttgaattact tgcttaaaac accaatgcac acatgccaga
     6901 taatgttcac aattatgtag aaatcttgct ctaccttctt caatgttgat attatctctc
     6961 ctagttgata ttatctttcc taaaatttct tttaattaaa aaacaacatt agttgatata
     7021 tcaagtatat tttaagcaac tgaaaaaaac aataataatt gatatatcaa ctaattaatg
     7081 tagattaatt catttttata atttatatac tttttaatta atctacctta tttaattaaa
     7141 atccttcctt tctatttatc cattttcaac ttaaattata agatttcatc agctatgttt
     7201 ttgcatacca ataagtatta aatatcaaat atatattcta ttaaaatttc taataatttc
     7261 atccttgatt tatttaatat ataaaaatat actaacttta atgattaagt tttgaaatat
     7321 aactaagaat ttgataattt attgagattt ttatactaaa atatacatac tatacaaact
     7381 taatttagaa gggagcattc ttatgaacaa taaaatactc gtcgtagatg atgaggaagg
     7441 tataataaca ctcttaaaag attactttga aatgaatggt tatgaggttt acactgctca
     7501 aagtggaaaa gacgcattaa aaaaaatatc caaaaatcca gatatcattc tacttgatat
     7561 aaacatgcct gaaatagatg gaattgaagt ttgtaataga attagagatt atgtatcatg
     7621 ccctattcta tttcttacag ctagaattga aaatactgac aagataaatg gttttcgtgc
     7681 tggtgctgat gattatattg taaaaccttt tgatttagac gaacttggag ctagagtatc
     7741 tgctcattta agacgtgaac aaaggaagtc aaatcaaact aaaattaaat tttataatga
     7801 tttaacaata gattacgaaa aaaggttaat ttgtatatat aataatcaga tttcactttc
     7861 aaaaaaggaa tttgatatag tagagcttct ctctatgaat cctggacagg tatttgataa
     7921 agaaaaaata tatgatagag tctggggata caatagcaat ggaaatagtg atgttataat
     7981 ggaacacatt agaaaaatac gaatcaaact atcaaaacat actcttgaaa attatataga
     8041 aacagtctgg ggagttggtt ataaatggat aaaataaata atatgtcatt aaaaaaagct
     8101 ttctttgttc ttactttatc ttcactaatt atagcatcag tacttactac tttcgcatac
     8161 attttactta ataatctata taattctata caagataagt atttaaaaac acctataaat
     8221 acaggtatta taaccatagt tcaaaacaat gtgaaccaat ttagtgatta tgataaaaca
     8281 ttacttaata taatcaacat acttcagctt gtacttccac ttatattttt tataggactt
     8341 ttattattag ctgatataat tttttacaag gtaaaattaa aaacacccat agaaatactc
     8401 aataaaggtg caatggaaat atccaacaac aatttagact tttgcttaga gtataataat
     8461 aatgatgaat taggtaatct atgtaatgct tttgaaaaaa tgaggtctga actaaataaa
     8521 aacaacataa agatgtggac tatgattaat gatagaaaac aacttaatgc tgctttttct
     8581 catgatttaa gaaatcccct aacagttcta aaaggttact caaactattt aacaaaatac
     8641 ataccaacag gtaagcttag tgatgagaag attttatcaa ccacacaact tatgtctgag
     8701 catattaaca gaattgaata ctatgtagaa aatatgagta atgctcaacg attagaagat
     8761 ttagttgttt caaaatctat gtcgaatata aacaagttta tagaaaactt agatgaaaat
     8821 atatctatca ttgctaaaca agaaggaaaa tcttttacac ttaaaagtca aataaataat
     8881 ataaatctat tttttgatga aaatatcatt cttagagtcg tcgaaaatat aatatcgaat
     8941 gcttttagat atgctagaaa taatgtatcc atacttatat atcttgaaca agaactcctt
     9001 acctttgtaa ttgaagatga tggtatagga tttagtaagg aatctctaaa attagcttta
     9061 agacctttct atagagataa gactttaaat gacagcaatg cacactttgg tatgggtctt
     9121 tatatctcaa aaatattatg cgaaaaacat ggtggctcta tttctattga aaataattct
     9181 actaacagtg ctaaaattac tgctaaattc tcaacaagaa attaaaatga ttttgtaagc
     9241 tttcactgtt cttatataag ctttgttagt ttagaattta taaaatgtat ttcaatttac
     9301 aaccaatata tatactattt tgtagaagtt gtaagagttg cttcaattat aatattttgg
     9361 caaaaggcat ttgaaacaat aatagaaata tatatttaaa tatgtagaat agtatgaaat
     9421 tagaattttg gaggtgatta tattaaaagt tttgctaata atattacatt ctctcgtatt
     9481 gtgtttgcat tgctaatgct tagttctaca ttctcttcac tgcctttctg gatatgttat
     9541 ttttggtgtg gaattagtga tatacttgat ggtcttattg cccgaaagtt gagacaacaa
     9601 agtggaatag gtgcaaagtt agatagtatt gctgatttcg tttttgcggt tacaattttg
     9661 gttactgtcg gaaaaaatat tgctcttccc atgtatctat ggtggtgtat tgttgcaata
     9721 gcattgttac ggttgattag ttacagtatt ggttttttta agtatcgcac attttcatcg
     9781 cttcatactt tgatgaataa aatcactgga atttctatct ttgcgtttcc attactctat
     9841 atttgctttg gtcttgatgt tgcaggaatt atgatatgta tcgtggcttt tctttcttct
     9901 tttgaagaaa tagcaattat gataaaatca aaagaattaa atcgtgatat aaaaagtata
     9961 tttatgtgac aacttagaat ttgtgacaaa aataatttat ataataatga ggaagtaaaa
    10021 cataaaaaat tatccacaag tttatgtgta aaatagtttt aaaacaatag agttgtattg
    10081 taaagccttt agtgcataaa ttacatttta aattaaaaat tatactgaaa ctgcttatca
    10141 gcactgcgaa ttatccgcaa atagtgaaga ctttttagat ttaagctaaa agttgggaaa
    10201 aaattgagtt ttaaaactta cactcttctt atatagaaaa ggagagtgtt ttttatgatt
    10261 ataaaagcaa aacaattatc aaaaatatat ggttctaata acaataaagt tatagcactt
    10321 aataatgtaa atttagaaat aaactcaggt gaatttgttt ctgtaattgg accttctgga
    10381 agtggaaaaa gcacactttt acatatttta agtggattag ataatcctac ctctggacaa
    10441 gtgttacttg atgataaaga tatatataaa cacactgaaa aagaactatc tgcacttaga
    10501 agaaaatcct ttggattcgt ctttcaacaa tttaatcttt tacctgttct tacagcatct
    10561 gaaaatattt caatgcctgt acttctagat aaaaaacaac ctgataaaga ctatttaaat
    10621 gaaatttcat cattacttgg aattgcagat agactcaatc atcttcccca tgaactttca
    10681 ggcggtcagc aacaaagagt tgcaattgct agagcactta ttgcaaaacc agatataata
    10741 tttgctgatg agcctacagg aaacttggac agtaaaagtg gcagtgaagt tatgaatctt
    10801 cttataaaaa cttcaaaaca gtttggaaag actttagtgg taattactca tgatgataga
    10861 attgcaaaac ttgctgatag aaaaatttca attattgatg gtgttcttat ggaggtgaaa
    10921 tagaaatgaa gaattacctt tcactttcaa taaaagaatt aaaaagccag aaacttatga
    10981 ctacattcat cattatagca atagtactat caactattat gacaactgtg gttggacagt
    11041 caattggtat cctacaaaat ttaagaattg aacaagcccg ttcttttaat ggtgatagac
    11101 atgtatcctt tcaccaactc actaaaaatc aagttgatga cataaagaaa gatgatagag
    11161 tttatcaagc tggtacttca ataactattg gcagtagtaa aataaaggat tctggtatct
    11221 ctgtacttgt aaaagagtat gataaaacag gactttctaa ctacccaaaa ttaatgaaat
    11281 taaaatctgg acatttgcct aaagataaaa acgaaatagc cttagatgaa aacacactaa
    11341 agcttatggg tataaaacca agactaggag tgactatacc tatgaattta gatatttcac
    11401 ttttaaatga taccatacca ccatataatt acacagctaa ctttaaattg agtggcattt
    11461 tagaggatga ttatacagga tatgtaagtg gtatagtaaa tggtattgta ggtaaaggta
    11521 catcagaaaa tctattacct aagagatata ttttatcctc tttggatttt aaaataaaac
    11581 agcaagaaaa gtttcaagaa atagtaaatc aattagctaa aaaaataaat ctttctcaca
    11641 attcaattca atataattgg atttacttaa atgctcttaa gatacagttt gaaaaagatg
    11701 aaaatagttc taatagtgat ggtatatcta tgattatatt ggtatcttta tttgttgcct
    11761 tattggtttt actggcctct ggacttgtaa tctataatat tttaaaaatc tctgttacaa
    11821 agaaaattaa agagtatgga tgtttaagag caataggagc tgaaccaaac cagatatata
    11881 agatagttat tttacaaatc ttaattttat gtactgttgc catacctatt ggagctgtaa
    11941 ttggaattat atcttctaaa ggcataactg gaatggtcac taatatctta aatccagata
    12001 tacttctagc aaatgataat aaagaaatta ctgagcttat acataaaaat acaacagcat
    12061 atatgttccc attagtatta agcactaatg tatctttgat tttttcattt atttcagcat
    12121 taccatcagc aatatatgct tcacatgtct ctcccaaaat tgctatggtt ggtagtacca
    12181 ccaaaatcaa aagaaaaatt aaaagagaaa aaacaataaa aaactttgaa agacatctag
    12241 catggctaaa cttaaaaaga aataaaggaa gaactataat aactatacta tcattattta
    12301 tgagtataac agtattcgtt gcactgagtg agttctctaa tgtattagat gtatctaggt
    12361 cagtaagtaa tttaaaagaa ggagattttt ccttaacaaa tgaactatct ggttttgata
    12421 aatcaacact agataaaata gctaaaatga aaaacgtcaa tcgcacttcc tttataaagt
    12481 actctgaata caaacagggt gaaatagata cagatataaa ttttgaaaat agtggtgaga
    12541 tgttaaaaat cattggaatt gatgagcaaa ctttaaaaga cttaatgcct tctattacaa
    12601 attctatact agaagacttt aaaaatggtt ctatctgttt tatcaaaaat ccgattgcta
    12661 tttctacacc aggtgtaaaa actagacata caaatttaaa acctaaagat agtatcacaa
    12721 tcaacaaaaa acaactagat atatatagta cagtagataa aatgttcttt ttacaaggca
    12781 atggctggat aaatggtgtt gatgttattg tatatgattc tgtttataac accttgacaa
    12841 ataaaaacaa attcaaccag ataaacattt atgctaaaga taaatcaaaa ttagaacaaa
    12901 taagattgtc tattgaacag atttgtgaaa ataatcctgg ctctcattgg atatcatata
    12961 ttgaatcaga taaacaactt aaagagagtt ttaaacaaat agaatttcta gcatgggcag
    13021 ttatattatt tgtgggattg attggtactt taaacatcat taacacaact catacaaata
    13081 taaatactag gactaatgag attggagtta aaagagctat tggtatgagt aatagtagct
    13141 tatataaaat gtttttatgg gaaggtgttt attatggaat ttttgctgct atatttggtt
    13201 caattgctgg gtatgccagt gctattatta taaacatggc aactatagaa aagtttgatt
    13261 tcactaatat accaattact tcaattttac aagctactat tatttctgta cttgcatgta
    13321 ttatagctac tcttattccg ttaagaaaag ttaaaaagat gaatataatt gactgtatag
    13381 atatcaattt ataactattt tacagataat aatataaatt aaattatcaa tgactgtctc
    13441 tattttcttt caaatctaac taataaatct ttttaactat aatataagct ttaaaaaagg
    13501 cctgtctcaa aatagagata agcctttttt cattgtcgga ataatgaaaa tatatttaac
    13561 ttcacaaaaa aagagtgcct cacgaattaa aaatttcgct ttgagacact cccctttaat
    13621 ttaaaatata taattaaatg ctatgccaaa atttcacaca tgctccacct gattttgaat
    13681 tttctatttt aacagaacct ccaagctgtt ccactaattg tttgacaatg taaagcccaa
    13741 gaccagaatg tccacctttt gtctgcctag cttcatctcc tcgataaaac ttatcaagag
    13801 ccttttttaa atctttagag ctaaaccctc taccagaatc acaaatctca taagaaatac
    13861 aatttttttc atcctttaca gtaatactaa tattaccacc tgatggagtg tattgcagac
    13921 tgttggatat gatattatca aaaattcgtg tcaacctatc cacgtcgatt tgaattgggg
    13981 attgtatatt cccctgcatt ttcaatataa gttcaacttc cttttgatga gcctgtaatt
    14041 catagtcttg caccttttgc cttaaaaatt caggtaaatt tataggaaca agatttaatt
    14101 gtatatttga cttttctaag tcagacgtat attgcatctt ttggacaaga gcagcacttt
    14161 tttctgtatt ttctcttatc actgtaagat acctatgaag tttttcattg tcatctgtat
    14221 tattaccaat aagtgcatct gtatatccta aaataataga aagaggagat tttaaatcat
    14281 gtgctagagc ttccaccatt tcaacacgtt cctgctccat cttccactgc gcagataaag
    14341 agccttttaa ttcgtctttc atttcagaaa aggcactaca aagtttaccg agttcattat
    14401 ctgaataata gtcgatttca aaatcaaggt ccttttcttt tatcttcttg gacgcatcaa
    14461 tcaatagatg taatggttga ttgatattct ttacaaagcg cttagaaagc catctagtaa
    14521 aacccacgat atatagaaat ggagaaaaca gagccattat aataactgca aatacaaatc
    14581 tccctctaat atttgcaaag gtgattttca cttggtagaa tagaataaca gcaccctcaa
    14641 tctttccatt atcccctttg attggaacag tatggatata accaccttta cgaacagttc
    14701 tattgataaa attattaaat aattcttctt ttgttttaaa tagtttttta gggttagtac
    14761 catataaaat attgccatta ttatccacaa cttgatatag catatcatcc ccacgaatcg
    14821 ttctttttaa accttcttca ttcgattgtg ataacaaagc tatgtttttt tcattgatgt
    14881 atttttcaat tctaggaact tgtcgctcat aatagtttgg tggatagata tccttattta
    14941 aggaataaat atacaaataa atagcaaata tataagtaat cactgtggca actatactgg
    15001 ctattataat aaaaataaaa gtatgtctaa attgggcaat aagggattga tttttcattt
    15061 aataacctct ctctctttac attttattcc acttataccc aataccccaa actgtggaaa
    15121 tatattcttt ttctggtgtc acagcagaaa acttagctcg tatttttttt actcgttcaa
    15181 caacagttga ggaatcacct tcagaatcac acccccatac tttttcatag atttgttctc
    15241 ttgagaaaac ttgtcctgca tggagtgcta gtaattcaac aatatcatac tctatttttg
    15301 ttaaatcaat attcttacca tcaattttaa ttgcacgttc cttcatatat aagcataact
    15361 tcccaaaata caaagtagat ctcttgttct cttcattgat atactgtgaa cgcttttccc
    15421 tacgcagatt agcttcaatc cttgccataa gttcacgcag tccaaatggc tttgttacat
    15481 aatcatcccc tccaaaggtc aaccctttga ttttgtcggt ttctgattgc tttgcactta
    15541 aaaatataat tgggcataaa acatcatctc taattgcctg acatacctca aatccattca
    15601 ttttaggcat cataatatcc agtataataa ggtcaggctc ctgttttgat aactctatac
    15661 ctgcctgacc atcataagct atcaacactt catgtccttt tgccttcaat tcgtcctcaa
    15721 gtagcattac taggtccatt tcatcatcaa taatcaatat tttactcaat ataacaccac
    15781 ctttctctta tgggaaggtc agtattaaaa caatatttgt ctactcataa cttttccttc
    15841 cctcccacat tttaaaccaa ataacgcctc ctatcaagaa tataatcaaa cctattgcta
    15901 ctactataag ctctatacta gctgtttgca tcactttaga gtaaaatgcc tcagttgaaa
    15961 tagtttcagc ttctttaata aaataaatcc ctggaaacat acctagtttt actggccatg
    16021 tccatggaac aaatgcccat actttttcac caacgctagt taatccaagt attgctgcca
    16081 tcaaaattcc accgatacta ataccaatag atgcacccat accccatgca aaactcaccc
    16141 aaagatgaat agctaatagt ggaagtgtcc caatcaccac aagtcctgct gctgacagga
    16201 ataaccatat tgttgctcca gatggcactg caatactcat tcctatgcag agtatcaacg
    16261 tagcaataaa tgtgcatata gttaggcaaa acagaagaaa aagaaatttt cccagatata
    16321 atctaacacg agaaatacct acacataaaa aaccattaaa atttccagca agctcttcct
    16381 cctgcactat aaatcctgct aaaataccta ctccaatagg aatgatgaat acagtccata
    16441 ctgtaaaaaa tccttcaaaa gcaaattctt gtgtacttcc agacttagtt gtgagataaa
    16501 aaaccacaca taatgaaaaa ataataggca tacaaagagt aagccactgg acagctgtcc
    16561 tctttgctcg aagccattct gatgataata gttttatcat ttgtcatccc tcctattgaa
    16621 ccaagctgca gtaagtgctg ttaatactat aaacacaacc aaagaaacaa caatcccaat
    16681 aggaatcact gaagtattca aaagtgggtc tccagcttct aatacagtac cgttaggatg
    16741 tatgttgatg attgggcata ccattctaac tgcccaactc caaggtactg caatccaaaa
    16801 tggttttgtc gcagcaagaa caccaaatat catacctaaa gctccaactc ccatacttag
    16861 gaacatacct ttccatgtag ctagccatag ctgaagtgga agtatagcaa gagaaacaac
    16921 ccagcataca atacttgccc ctataatctg tccaaaagga actgaaccag ctttcaatat
    16981 taaaccagtt ataattgtta cgaatattaa gactagcgtt gaaataaaac tgtagactgc
    17041 catagctata actttattaa tccaaagtgt cataggagac acattgtgtg tacgtaaagc
    17101 acgataattt ccagcttttt tttcctggaa agctaccaaa gtagcaaaca atgcaaatcc
    17161 aataggcaga aataaaaatg accaccagtt aaaaattaat gctaaaagat tttgccacgc
    17221 ccaagaagtt gtttgagata atggattttg catgagtgtt gattgcatta taaatgcata
    17281 tgctgcaaaa gacactggga aaaaaacaat aagtttaccc ataaatgttc ttttatactt
    17341 taaaagttct gattgtaaag cattcatctg ttttgtcctc ctttaagaat aacatctgta
    17401 aaaaattctt ctagattttc attagggtca ggcattcctt gaaataatag tcgtcctcca
    17461 tttataattc ctatattatc tacaacttga gcaacctctg atagaatatg gctagaaaga
    17521 attacagtta tacctttttt tggaaaagaa gcaatcaatt cacgcaattc ttgaatgcca
    17581 aaggggtcaa gaccattggt tggttcatcc agtattaaca actctgggtc actcaaaagt
    17641 gcaatagcta ttcctaacct ttgtttcata cccatagaaa attgtgaagc tctcttttta
    17701 cctgtatttt tcaaatttac tatttccaac acttcataaa ttttatcttt aggtattccc
    17761 aatatttttg tatgtactaa caaattttcc tctgctgtaa ggtttccata caatgcaggg
    17821 gattctatta aagaacctat ttttgcaaga gattctcgtt tccaaggctt tctatcaaaa
    17881 ataatacgac catctgttgg tcgaagaaga ccaacaagca ttttaagtgt tgtggacttt
    17941 cctgctccat ttggtcctaa aagtccatat atactatttc gttcaatttg tagagaaaca
    18001 ttgttaactg ccatttgttc tccatatctt tttgataagt tttttgtttc aagaattaaa
    18061 tctttcatat taatttctcc cttcttgtaa taccttaaat ctattactaa gagaatacta
    18121 acatgaaaaa ataacaattc tataacacct actaatttta ataaaaatta aaataaaaaa
    18181 tagagttacc aattttattt tggcaactct atttaagttt atgttttaca gttatattag
    18241 atttaagctt agtttcatta tcacactaac ttcaaattta ctctataatc cttaaatcaa
    18301 acactaattt attaatcaaa cactaatcta ttaatttata tttctttaga catctaatat
    18361 agtttgctac taaataataa ttatttatat catatttatc taatccttta aaagaagtta
    18421 tttcatcatt aagctcatca ctaccttcta caaaaacaca acctgtttca aattccatac
    18481 ctacaataat cttacagcca ctataagttt cctcttgagt atcgtacaat ttttttgcat
    18541 ttccttcatt tggaattgta aatacaatag gttttaattc tttatcactg gaaatctttt
    18601 gtgaaaaagg cttgtttaac ttaatattat tgataactac atgtttaaat tcctctgaag
    18661 tttcctctac tattacatat tttcgcttta aaaactctat tatttctaaa acagacttag
    18721 aatttacttt taaaatactt ttatattttt catataaaga tttccactgt tcaatttttt
    18781 cctgtggtac ttcttggata tgtgtactta ttttttcttg agatattttt ttcaattaaa
    18841 ctctcctttc aatacttaaa tatccttatg aatctcacat gactaaagtt acaaggtttc
    18901 tacttaatag aattttgcat acttaaatat gtcttattaa ttctctacag gatatctccg
    18961 tagttcctac gattcttaca taagttacct attttaaatt gttattagtt agattataaa
    19021 aattatttat tttatcacta atataatact cttaaaaact ttacaaatca atttaaattt
    19081 gctacctttt atttataaca acttatagta catttctcct atgcttttca atatattact
    19141 tttaaaagga ggttttcctt atgattttaa atagaactga gcttttccga ggatgttctt
    19201 taaatagatt taatgagata tgcaatatat tatcagtaaa taaaattaaa tataagtata
    19261 aagtgaaaaa taatgcttac tctaaaaaac ctttttttaa tgaaataaca cttggcaatt
    19321 taggccaaaa ggaagatttc ttttatgagt acttaattta tgttcataaa gacgattatg
    19381 aacaggcaga gtctctaata aattctaagt tgtgatagat tatttataaa acatgacatt
    19441 ctgttgtcat gttttatatg ttattatact ttcaaatatg ctactatatt ttcaaaattg
    19501 tgtgctttaa aactagcttt ttatagtaat ttaaagctta aaactaagga gactcgttat
    19561 atgaaaataa atataaaatc aaagttaagt gaatttatta aacagaacaa tctttttgat
    19621 gacagcagaa taatatccta ccttcctaat ataacaatag aaacagacaa aataaaaact
    19681 ataatgatta atgaggttgt cccaactaac accaatgacg atttttatag tgtagataaa
    19741 gatgctgatt atttaaaaac tactattcct ttatttgaca gtgcaggaat aaaagtatct
    19801 aacataaatg atatcctaga tatgggtatc tatataacta atgcagtaaa acttcctaaa
    19861 tcagaatata caataactcg tgatacaatt aaattacata tgcctatttt agaagaagaa
    19921 attaaattat ttaaaaacct agaggtagta atgttaatgg gagatgttgc aaaaaaatct
    19981 tttaatatga ttactaaaaa gcatataaaa aagaatgtca tcccttccat ttcaacatat
    20041 aaacttcgta ataatgaact ttattatgat aatttaagag tatttccatc atatattatg
    20101 actggtggaa acatactgat tgaaaaatca aaatttgaaa tggcatcaga agatataaaa
    20161 aaaatgttcg agattataaa cggttgatat tacaaaataa taaaaactaa tataaaataa
    20221 aaagtgcctc aaaaccttct atttatgagg cacttttatt ttatattagt gtaactatat
    20281 actattaaca taatttatta tttatattgt tctttttaat ctctattcca tttagtctag
    20341 gtaacattac tctttacaag attactttat atttctttta tatctctaac atttttattt
    20401 aataaaacaa ttattaatac aagtcaatta tatctattta cctaaaaata tatctttcac
    20461 agtaatatct ggatggtgat acttcttcct attcgttaaa aaagattttt ttacattaat
    20521 agcctctttt ggacaccagt gaaaacaagc taggcatctt tcacactcat taccccactt
    20581 tggcttttta tcaactatac ttatattctc tacaggacaa acccttttac atgtcccaca
    20641 tccattacat ttattttctg caaaaaattt agtagttgca atttgcatat tcttgcctac
    20701 taaacgaagt acaacactat ctatatgtga ctttaaattg ttttttcctt ctatatttcc
    20761 aatctccaag ttattgatac attttgcaat ctcagctacc ctattagtct gatttttcaa
    20821 tctttcttct tcaacatctg gaggtgttat caaagcattt ccaggcatat tgattaaaaa
    20881 accagcagat aattttttcc cccttttttt aagtaactta tctatagtaa ataaactatg
    20941 tccagctacc ccattacaag tggcaatggc atatatatga gtattaatat taaaatttaa
    21001 tttctctaca aaagacttta ctatatcagg aacatcagca aaataaacag gaaaaacaat
    21061 taccaatata tcttcattta tgtctatatt attttctttt ctatgtatag ctaagggtat
    21121 aacttcttta cttccattta acgtttcttt taaaatattt gaaactacta gcgaatttcc
    21181 tgttccagaa aaataataaa tcttactatt cattcttatc cctctttcta tatttctaca
    21241 tcatcaatag ttaaaaagtc tcttaaaata ggatttatat ttactttcca attctatcca
    21301 aaatatcagt aaacaaaggc aattcttcat cagagataga tttaaatgtc tctgttgcat
    21361 atatacttgc aatttcattt aatggttctt ctaattctct acctaaatct gttagaaata
    21421 tttgaaactt acgtctatct ttaacatcta ctttacggac aattaatccc ttatttttca
    21481 taacatctaa gattcttgtc gtattagatt tatccttaca tgatttttca cataaatcta
    21541 tctgagaaat tccatcttgc tcccatagaa accttaataa cgcataatgg tcagttgtta
    21601 tatcatatcc attttgttta aacatctttt ttaaatcatc ttttactttt aacgaagtac
    21661 ttactaactt agttgtagct tcatatagtt tctcaaaatc tttcatttta cctccattta
    21721 aataatccct tgctcctccc atctatcaat tattccctta tattgctcaa tatctttaaa
    21781 agccattggc tttaaaacag catttatagc aataaaatta tagatttgag aaagcacagg
    21841 tggatttttc ttttcctcta tgcaataaat aaatttttta gatacctttt gtatctttga
    21901 ttctactttt tcagttatag gattttgatt aaatccagtt tttatagata aactaccaca
    21961 aacataacct cccgaatcta agaccatgga ttttataaaa gaaattgctt ttgaaccacg
    22021 tgcattttca tatgtagtaa ctgctataca tggcttacga tacaataatc tttcaagcat
    22081 catatgtgct ctatctgtaa acaccttgaa aagtccagtt acactacttc cataagttgg
    22141 gctaccaaat ataacaccat cactcttagt aattatatca tgaatatact ctactttatc
    22201 attttgattg atacacttgc ccattttata acaatttaaa caaccaatac aatatgatgg
    22261 atttacctca cttaaatcaa aataattaat ttttacatct ggtattaatc tttctatatc
    22321 tttatacaag taagtcaaaa cttttgatgt agctccattt tttctagggc ttccatttac
    22381 aactgtaatt atcatttcta tatctccttt ttagttgtta tatcaacaat aagtatatca
    22441 actatatttt tagctgtcaa tataaaccat ttatttaaag ctatacttac acagcttaaa
    22501 taaaagtttt atttaactac atgtgcttat ttaatcaact ataaatgaat tatttttaat
    22561 aattgacaaa ctaaattaat gataatatac tttatgtatt acaaatgtaa gtagaaggag
    22621 gtatagtatg aaaaagttac cacatatttc agaagcagaa tatcaagtta tgaaaattat
    22681 ttggaaatat gctcctatca gcactactga agtaattgaa aagttggtag aaacaagtac
    22741 atggagtcct aaaacaattc aaacaatgtt attgagatta gttaaaaaag gagctttaac
    22801 atatgaaaaa aatagcagag tattcgttta tactccactt gttaaagaag aagaatacgt
    22861 agctaaagaa agtagttctt ttttaaatcg tttttataat ggtactctta attctatggt
    22921 actaaacttt ttagaaaatg ataaactatc tgaagatgat attgaggaac tgagagaaat
    22981 cttaaataaa aggacgacta agggggataa ataaatatgt atgtcccatt ctttatacga
    23041 tttttactca gtacattaac cttatcaata ttaattgttg taattttact tgccaaaaaa
    23101 gtatttaaaa aacatatttc tgcaaagtac caatacaata ttggatttat attgcttata
    23161 atgttaataa ttccatttgt ccctcttaaa tatattaatc ttggaaatgt atttaactat
    23221 ttatatactt ttaatcaact tggaagcaat actaataggg cttctatgat aaaaaatagt
    23281 ccaaattcta taattaataa ctcaaatgca ttaaacgatt tttcagtatc cctaaaccaa
    23341 gttaattttg atagtttaaa tattttatta ctaatatcat ggataattgg aattttaatc
    23401 atgatagcta ttactattca ttgcaacatt aaaataaaaa atatgaaaaa atcaatacaa
    23461 attttaagag atgatgagat agtatttata tttgaaaagt gtaaaaaaga tattggtata
    23521 aataaggatt ttatactatg caaatcacct attataaata cacctattac atttggatac
    23581 tttaaaccac acattatatt accagataag tctatatcta aattatcttt aaaagatata
    23641 aaatatatct tacttcatga attacaacac tttaaaaata aagatatact gataaattat
    23701 ataatgtgct tccttcaaat attatattgg tttaatcctc ttgtatggta tgcatttaaa
    23761 gaaatgcgta tagaccgtga aattgcatgt gatatttcag ttttaaaaaa tcttgataaa
    23821 gatagtcata tagaatatgg acaaactcta ataaactttg tggataatat ttcaagacca
    23881 tcaaatctta cacttacatc agatattggt gggtcaaaaa aacaaataaa aaagcgacta
    23941 ttgaagataa tggattttca taatgaatca aatacgttaa aattcaaaag cattttaatt
    24001 tttacattga tagctttaat tgtatttgga aatattccca aactatctat tatggcagat
    24061 atcaatgaaa aatatagacc tacaaatgaa caaactgtgt acgaggactt aagtcagtat
    24121 tttaaaggtt ttgatggaag ttttgttatg tatgatttaa aatccaagca atatcatatt
    24181 tacaataaag aaaaaagtaa aacaagaatt tctccaaatt ctacttataa gatttatagt
    24241 gccttattgg gattggaaaa tgggataata acaagaaata attcacatat cccttgggat
    24301 ggaaagcatc attctaatag ttcttggaat gaagaccaag acttattttc tgctatggaa
    24361 aactccgtaa actggtactt tcagactcta gataaaaaaa cagggctaaa aaacatacaa
    24421 acttatctta ggcaaattgg atatggcaat tatgatgttt caggtggtat ctcaaacttt
    24481 tggctagaat cttcattaaa aatatcacct attgaacagg tagaattact tgaaagtttt
    24541 tatacaaata agtttaaatt tgaagataaa aatatagaaa cagtaaaaga ttcattgtta
    24601 atatcaaaaa aggatggggt atcacttttt ggtaaaacag gcactgctaa tataaatgga
    24661 aaagatgtaa atggttggtt tataggttat gtggaaaaaa atgaaaatac ttatttcttt
    24721 gctacaaata ttcaaagcaa agattattct aatggtagtt cagcatctaa gataacatta
    24781 tccatattaa atgacaaaaa aatctataat ccttaatata tttactgtac attctaaaaa
    24841 attcacataa ttttcatatt aattatcaat taaattcata tacaaggctt attatataaa
    24901 catagaagat agtaaaacta gcttaaaaac ataatataat accctataca aatagtggca
    24961 actctccctc acatcctcaa ttgttgccac tatttaattt tttgtatgaa gttaaatata
    25021 ttttcatcat ttcaacaatt tgggtgcaat acaatctcta ttttgaaaca acctctttaa
    25081 ttgttttaga gtttatgaat tatttctcat actttaaaaa gattgaatta ctcttgataa
    25141 tcttcttttg tagtcattac atatcaccta ctactcaaca catattcttt gacctatttt
    25201 tacatccttg tttatatcca aaatatttac cttcttacca tctggaaaca ataccattgt
    25261 caaagtagac tttcctaatt catgtattct ctttaaatca acattaacaa gaacatctcc
    25321 ctgtttaacc atatctcctt gtttaacagc aacatcaaag ccatctccat ttagtgcaac
    25381 tgtatcaatt ccaacatgaa ttaatacttc tccattagtt cctttaatcc caaatgcatg
    25441 tccacttgaa aatactgttt ctaatttacc tgaaatagga gaaacaattt ttccatctat
    25501 aatatcaata gcaaaaccat cacctaacat ttttttagaa aatgtttcat ctggtacatt
    25561 ttctaatgca acaattttcc ccttagctgg agacacaaag ttttcattat tttcattaaa
    25621 cactaattct tcgtcttcat cttcatttat agcttcttta ggcactccaa ataaacatgt
    25681 tacaataaag cagaatgcaa ccacaaatat tgatactaat aagtatgtga ttaaattata
    25741 tccatcatag atatacatta aataagaagg taaaactgct aatccatatg aattagattg
    25801 aatatgtaaa attgataata ttgctgctcc taaacctgaa gatgcacaca taataatcaa
    25861 aggctttaaa ttatatcgaa gctgaatccc aaataaaaca ggctcactta taccaaaaag
    25921 ttgagatagc attgctccaa ccgcagtttg tttaacttga ttatttttag attttttcat
    25981 aaatgctaga catgttccaa tattcgcaaa tccatacatt gcacaaagag taataagggc
    26041 attaaatcct gtatttgcta atagtgatgt ttcaatcatt acataagtat gatgtaagcc
    26101 agtaataaca gctaatggat atgtaaatcc aataataaat cctccaattc ctaaaggcaa
    26161 atcaatcaat aagctgatga tatcaaccat ttttaattct attgtatgca ttatagggcc
    26221 tacacctaac aaaataacta acattgttat tagcataaca aaaaatggtg tgaaaataag
    26281 gtctaataca ttaggcatat gtttacggaa ccatttttca agattagctc caataaatgc
    26341 tgtaacaata gctgttaaaa cacttccttg acaacctaca ataggaataa atccaaatgc
    26401 cataattgct tcaatttcat ttgatgggtc agcaacagaa tatgcattag gaagtattgg
    26461 ggaaactaac ataagtccaa taacaagtcc aataacaggt gttcctccaa atactttaaa
    26521 tgctgaccat acaataattg ctggtaaaaa agcaaatgct gtttctgtaa gaactgaaac
    26581 aagtgtctga atatacaatg gaatatttgc agaagacatt cctaataatc caagtacatt
    26641 atcattaaac aaacaaccct ttaatcccaa gaataatcct gttgctgcaa taactggaat
    26701 aataggaaca aatatatctg ctagagttct cataactttc ttaaatccag tttcattatt
    26761 tttaactaat tcatcttgtt ctttttttga taaagttttt aatcccattt tttcaacttc
    26821 tgcataaact ttattaacta ttcctgttcc taaaataatt tgatactgtc cagaagtaaa
    26881 gaaaacccct ttaacctcat caactttttc aactttctta tcattaataa tttctctatc
    26941 tttaaccatc actcttaatc ttgtggcaca atgtgtaata gaaataatat tatcttcacc
    27001 aataatttta ataagctcat ttgctatttt attatattta ttcatttttc tacctcgctt
    27061 tcaataatat tgcatgaaat ggtttcaaac gcactgtttt atttaatgga tttatatcat
    27121 ctaaattttg gaatacaata tcatattttt cttctactct tatttctaca ggtttatcag
    27181 aaaaattata ataacaatca ataactacca aatctaattg ccttctatac gcaataacat
    27241 catcactttc tatatcaata ggttctattg aaccataaat caaacaatca gaatactcac
    27301 tatcttgtct caactttatc atctttttat aaaattctaa aatactctct gaattgttaa
    27361 tctgactctg tgcattaata tctttataat tttcaataac ctttaaccat ggtgttgtat
    27421 ctgaaaaacc tgcattttct ttatctgccc atggaaatgg cgttcttgca ttatctcggc
    27481 ttcttaaatt cacaaattct aacgcttctt cttctgagta accttcatct attgaacgat
    27541 agtattggtc aatgcttgat aaatcattaa aatcatttat gttatctctt ttaaaatttg
    27601 tcattcctaa ttcctgtccc tgataaataa atggtgttcc tcttaaaaag aaatacattg
    27661 ctcccaacat ttttactgca tcatcattcc tttcgtattg caaaagatac tttgttgtag
    27721 ctcttggttg gtcatgattt tcaataaaat tagctgccca tccatgttcc tgaacataca
    27781 tttgactatc taaaatgcat tttcttaaat ctggaattgt ccatgaaatt cttttaaacc
    27841 actcactacc agaagcaaca tctaagtcag catgtttaaa gtcaaagacc attgaaaaga
    27901 aaccatcttc tccaataaaa tcacctagct ggtcatagct aatacctgct gcttcagcaa
    27961 cagtcataca atcatatttt ttaaacgtat tttcttttaa ttcataaagc attttttcta
    28021 ttccaggctg atttctaact gtttttgtac atttaacaag accatcaaca ccatcacttt
    28081 ctaaactttg aaaacttaaa ttctttttga tgaatgtaat agcatcaact ctaaatcctg
    28141 ccactcccat ttgagaccag gtattaatca tttggtaaag ttcacttctt aatattggat
    28201 tttcccaatt aaggtcaggt tgttttttac caaaagaatg aaaataatat tcgtctctat
    28261 tctctacctt ttcccaaaca cttccaccaa aaacagacct ccagttattt ggtaaatcgt
    28321 ttcctttttt aaaaatataa taatcatgat aagaactttc tggatttttt aatgcttctt
    28381 gaaaccaagg atgttcatca cttgtatgat taagaactaa atctaatata atcttgattc
    28441 ctctatcttt actttcttta attaactctt ttaaatcttc catacttcca aattcacttg
    28501 caatatccaa ataatcacta atatcatacc cattatcgtc cataggtgat ttaaaaattg
    28561 gacataacca caatgatgta atacctaaat cttttaaata atctaaacga gaaataattc
    28621 cctgtaaatc tccaattcca tcattattac tatcttgaaa gcttcttgga taaatttgat
    28681 aaacgatttc tttttgccac catttctttt ccataaatta ctccttttta tatgatattt
    28741 cttcttttta attctttata aattccatta tcgaatatgt cctcacatat agatgtcgct
    28801 atatctttaa gttgttgatg actatttttc attgcaattg taacgtctga tgcttgaaac
    28861 atgacaatgt cattttgacc atcaccaaaa catatggttt ctttttgagt tactcctaat
    28921 ctttcttgta atctcttaat tgctttgccc ttatgaaaat ctttttgaat aatttcataa
    28981 tactgactag aaatatctct ctgtgctaat tccattttat cttgtagtat atctttcact
    29041 tcgtcaaata ccttttcatt tgaccataaa caaattttat gtatatcttg tgacttatac
    29101 tcttcaatgt tattttcata tgttattttt tcttggatat gttgtttatt tatacaagaa
    29161 ttagttcctt tcaactgatt cattgtttca aatatttctt tggctttttg attcatgaaa
    29221 actttttcct gactctcaat cgaaaaagca acttctctct tttttaataa acaaacaact
    29281 tcctttatca atctttgatt aaaagattga ttataaagta attcaccatg atattgaatg
    29341 taattacctc ctcctgcaat atatccatca actcctaatg ataaaacatc atcttgtatt
    29401 gtacccatac ttcttccagt acaaataaca acactgcaat gattcttttg acataaacgt
    29461 atagcatgct ttgcagattc tgggattcca tatacctcat ctctaagcgt accatctata
    29521 tcaagtatta ataatttgta caatttcatc ttcctttctt actatcaaaa tcataatagc
    29581 attcaaaaaa aaagatatca atattttgat atcttttaaa aaatatgttc atttttagca
    29641 caaattttca ttttcgggga atatgttcac tttctaaata catcttgtat ttaatataaa
    29701 gcagttcaat taaaataaaa taaggtgttg ttacatcgta gtccagttgt ttatctacag
    29761 aaatagatat agattgaata tacaggtttt catcacataa tcttgctaaa ggattactta
    29821 tcatttttgt aatagaaacc atataaattc ctttcattct catttcttta gcaaaatcaa
    29881 taattgtaga tgcatctcca ttcaatgaaa taaagaaaat catatcatct gtttttataa
    29941 aatgattaag tgcctgaatc atatcataac cataaacatc atatataatt ttccctgttg
    30001 gtaagaaaat ccttttcatc tctttagcaa ctctttcctg agaataacct tctccaaaga
    30061 cgattatacg atttgccttt ttcattcttt caaacataat cgaacaatcc ttcttctcta
    30121 tatcatttat caccttatta taacaatcca ttaattggtg tttactttga tttttatatt
    30181 ctacttctgt ttcatttaag cgtataataa ctcttaattc actatatcca ggtaattgta
    30241 gtttttgagc aaaacgagaa agtgcacttg tagatatatg gtatttgtct gcaaattcat
    30301 ctatagaaag tttaatacaa tcttctttat gattaagaat acactcacag atatacttat
    30361 catttgctgt aaatgaatta taatatttat tgaaaagtcc ttcaattttc attcttttct
    30421 ccttctatac tctatgtaat tcatatgaag caaatctaat agagcataaa atgctcctac
    30481 gacttcataa gatatagctt gtaatgtatc aagtttttgc gtttcaacat acagattata
    30541 ctcacaaagt gttgcaattg tattattatc aagcctagtt aaagaaatcg tatgtatatg
    30601 attgttgata aattttgcaa tttcaattcc tgcttttgtt tctccagaca aagaaatgat
    30661 aataaataaa tcactttttt gaaatgattc tctcataaat tcaatttcac ctatatcaaa
    30721 taagtcaata acacatttac ctactgaaag aaatattctc tttatttctt gagctaaact
    30781 tttctgttca ttacctgtcc cataaatata aattgtttct gcatcatata ttattttaca
    30841 aatatcttga aatgatattt tttgtaattc attcattaat agtcgataat tctcgcaaac
    30901 atcatgaaaa ttattatcat tattaacaaa ttctagttga ttatttttaa gtaaatactt
    30961 taaatcagag aatgaatcta atccaatttt tctacaaagc cttaataaag tagctctaga
    31021 aacattacat tcatttgcaa ttttttcaca cgaaaaatta cggtattctc tttgacaaat
    31081 caatatttgt ttaataataa ttttatcatt ttcatttaaa ttatcataat tttggttaac
    31141 taacgattct aatctcattt tttccactcc ctaaatatta ttttaatata cattagttgc
    31201 tttttctagg gaagagtctt aaaaatattt ctattaagac aaataaaaaa gagctatctc
    31261 agaacaaatt taatttgctc ataccacagt tctattataa ataaaaaatt tttcacatta
    31321 ttttttacac tatataattt ctatttttat aattaaaccc aatttataat atatagaacc
    31381 atatttatat ttttatctcc tgatttgttt taattacatc tattcatttt ctatcttatt
    31441 taataattcc tattacttga atatttactt ctttgagtaa atttcatagc taacaaagct
    31501 aaaattatta ttataaatgt caaaatacaa atataattca tattaaaaaa gcttccatct
    31561 ctttcttcta tataagtcac aaaactaata aaccattgtg ttgggcttat aatactaatt
    31621 ttttgtaaca ttgttggcat tttttcaact gaaataaatg aaccaccaat aagtgataat
    31681 ataagtgata tacatgtaga aaacaaattt gcatgcattt ctttattgaa taaagaagat
    31741 acaaatgttc caaaagaagt tgccaaagct gatatccata ctcccattaa aattaaatct
    31801 atataatcca tactaatatc aatattaaat aacttaatta tagatattga aactatgtac
    31861 tgaaaatacg ttattgtaaa gttgtataac atattaccta gcacatatcc tcttatattt
    31921 tgtggagaat atagcactct tgtaaatgta cctgagtttt tatctttaat aatcattgat
    31981 gctgttacag tagatgttat cattaaaaat aatacgataa atgcaattat tctttgtaaa
    32041 actcctaaag tattttcttg taatttactt atatctacag gaactgggtc ttttttatat
    32101 gtttctatta aatactttaa tgtatcattc gtatttttat cttttataga atataactca
    32161 aaaccattct tattaaaaca tacgacagct gaatacttgc ctgttataat atcagtttta
    32221 attgttttaa aatctgcaat ctctgtatta atcccttgag tattttctaa agccattatt
    32281 gtattttcat aggttctttt ttcagattcc tttagaatgc attcgttttt gtactcatct
    32341 aaaataccaa tattaaaaga tggtttactt atgtaatttg ccaatactcc taaaactact
    32401 ataattatag gaaataaaag tgtaactaaa aacactattc tcttatttat atttcttttt
    32461 aagttactat taaaaacatt tattacattc actatataaa gacctccttt ttaaaaaatt
    32521 tgattgtaag tattgtcata aatatgctta cagctacaaa tatgcatgat atattaaaaa
    32581 ggagttgtaa attattatca tagatacaag caactatgcc tctattaatc catgttaatg
    32641 gtgatatatt aatgattaat gaaataactg gattcaatga actaactgga aagaacactc
    32701 ctcctaagaa gccaaaaata actatcggta tattaatgat attacgtaac atatctaaat
    32761 ttttacaaac aagacccaaa aacaacccca tagatactac tgcaatagat tcacacatta
    32821 aaaagaaaat aacaactaaa aatttcccac caaaactcat atgaaaaatt cctcttaaca
    32881 ccactaaagt tatcaaattg tatatcgaaa atactgttgt gcaagaaaaa agttttgaaa
    32941 taactaaatc tactattgaa acaggagaaa tcatataacg atatgatgtg ttagaaattt
    33001 tttcatcttg tgctacatat gaaacactaa taattcccat aagaacacaa aatggtattg
    33061 taacaatagt ataataatta tatgatgtaa attccttacc ataagacttt gatgtcaaat
    33121 agcctaataa tactatgatt attactggaa aaacaatatt gtaaaacaga ataaaaaaat
    33181 ctttacttct tcgttttatt cctaatttaa acaatgttaa aaaacatctc atctatttat
    33241 tcctccaaat ctctcaaatc tgtacctgta agatatagaa aaatatcttc taatgtctta
    33301 caaccaaatt ttaaatattt atttttatat aaactcttgt ctaaatcttc tataattact
    33361 cctttatcta ttaaaacaat tctattacat aaagtttcaa tttcctccat atagtggcta
    33421 gtatatatga ctgttgtgcc attattatta atgcctttaa ttgcttccaa aattttattt
    33481 cttgattgag ggtctatacc tactgttggc tcatccatga tgagaatttg tggactatgt
    33541 gcaattgcac aagctatgtt tagtctacgt ttcattccac cagaaaattt tgatggaaac
    33601 tccttatggc tttcccaaag gccaacaaat tccaaggcat atttaattct ctctttaagt
    33661 tcattccctt taaatccata taatgagcaa aaaaatttaa cattatcata tgcacttaaa
    33721 tcttcatata ttgctaattc ttgtggtaca actccaagtg agcttttaaa aatattttgt
    33781 tgattcttaa tatcttttcc tttatagtat atgcttccac tgtctggaga cacaatcgta
    33841 gtaagcatat tgatagatgt gcttttccct gctccatttg gtccaataaa acctaaaata
    33901 tctccttcca ataacttaaa actttctctt gatacaactt ccttattgtt atacttctta
    33961 gataaatttt taatctctaa caatacatta ctcatttata aaatcctcct aatatttaac
    34021 caacattata tatccaatat tgtatatata gtttttttaa aacacgagtg ttttactcgt
    34081 gttattataa taaaatttat tacttatttt gtaatttcag tattatctta tctatatttt
    34141 ctatagcttt atctggatta ttaattattt catctctaag tctttgaact tctaataact
    34201 catttgtcgt atcagatgta aataaaaaat cttcttctat atttgaaaag tctatagatt
    34261 taattatatt ctgtgtctcg caaccaacag atatatactt atcgatatta tttaatattt
    34321 cttcatgcca caaaatttga taattcagat tatctatagt catatcaaat gcaatttttt
    34381 ctgttgcaag actcttttta tcaatttttt taatctcttt ccaattttcc caatacttct
    34441 tctgctctat aagatatttt atatgttttt caagattttt ttgcaaagta tccttaggta
    34501 atacatccaa aatattatgt aataggaatt tatttgaacc agttggaact attggcatct
    34561 gaagctcttt ttgtatttct tcccttaatt ctaatttacc gctttgagta atctcataga
    34621 ttttacgaat cctagctcct gttttttctt cttttaaaac tctaactcct ccatcctttt
    34681 ctaattttgc caatgcataa tatattgacc cagattgtat tttagtccat ctatctgcac
    34741 cagatacttg taaaaacttt tgaatctcat acccatgtgt tggcttaata tttagataat
    34801 ataaaattaa agtgcgtatc ataaaaattc accacctata ctctatcttg gatattatat
    34861 tatcaccaac attggatata gtcaatagat aacataggat atattacaac ttattatttt
    34921 tattatttaa tacaaggagt tccatgagac atacatatcc attcatattt taaattatcc
    34981 aattctctta tagattttat catcttttta taatcccaat tccatggatt aggataagga
    35041 actatatttc cattcttatt tttgactaaa tcacctgcaa ataatacatc ttcaaaaatc
    35101 atgcagacat gccctggagt atgaccagga gtatggataa tttttatatt cccaatctgc
    35161 atattctctc cataaggttc aacatcctta atgagccttc tggaaattgc ctttccaata
    35221 aacttcttaa atccaggtct atccttctct cctataataa aaggtatatc ctctacatga
    35281 gcccatactt ttgctcctgt tttttctttc aataatttaa tatagatata tggtcaacat
    35341 catgatgagt taataaaata tgcttaatat ctgtaagttt aatgccaagt gtttttaatt
    35401 ctttaattat atttttcccc ataaaaggaa gacctgtgtc tataagaata atttctttat
    35461 caaacacaat aaaacaattt gagccacgag tactatctaa cattaataca ttttctttta
    35521 tcttcataaa taaattcccc ttatttggta ttttacctat ataattaatt aataaagtta
    35581 taaatagtta taatacttga tattaatttt attttttatt aaagtatact ataggtatac
    35641 aagtattata tttacataag tataccatca gtatactttt ttatcaatag aaaggaataa
    35701 tttatatgtc agaattatca aaaagagata aagaaaaaat acaaagagaa aatgagatta
    35761 ttgataaggc agaaaaatta ttttgtctta atggatttga taatacaact atgaatgaat
    35821 tagcaaaaga agttgaatat actaaacgca ccatatacaa gtacttttca tgtaaagaag
    35881 atttattctt tgctgttgtc ttaagaggat ataaaagact ttgggataat gttaaaatag
    35941 aaagtgcaaa aggcaaaaca gggtttgaaa aaataaaact ttcatacttt gcttttcata
    36001 aattttactc tgtagaacct tctctattat gccttatggg aatgattggt attgtaaact
    36061 ctgaaaaatc ggatactgat atgctgttta aagaaaagtt tttttctttt aataaattta
    36121 tgtttgatga aatacaagga atgtttgaaa ttggaaaaaa tgatagaagt attaggcatg
    36181 atattgaaat acctactctt atgtattcat caatatttac acttacagga ttttttaatt
    36241 tactatctgt aacaggaaaa tcatacctga acaactttaa tatagatgag gaaaaattta
    36301 ttgaaacaac tcttgctctt ttaatagatt caattaaagc ataaacctaa gtttataaat
    36361 taaagtttat atacttaaat gataattttt tctatctcta atataaaaaa tattaaacat
    36421 aaaactaata acttagttaa tggaataact aaattactga aaggattaaa agtaaatggc
    36481 taaaatactt cttttagaag atgatgatac aattacattt ggaataaaaa cttcccttga
    36541 aaagaaaaat cacactgtat gttgttataa tacgattgct gaagctaaaa aaaattttga
    36601 taaaactatt gatttaattc tgcttgattt aaatctacct gatggtattg gatacgagtt
    36661 ttgccaatat gttaaaagta tagaagatac tccagtaata tttttgacag tccgtgatga
    36721 tgaaaaagac attatacgtg gattagatat gggtgcagat gactatgtgg ttaaaccgtt
    36781 tttgctctca gtacttcaat ccagaattaa tgcagttctt agaagaactc attcaaatac
    36841 taacaatact attacatgtg aaaatataag cttgaataag gttgaagtca aagcatattt
    36901 agataatgtt gaagtacctt tgacagcagg agaatataaa cttcttctaa gtcttatgga
    36961 aaataaaaat agagctatga ctcgtacaaa gttactagaa atgctctggg atgtagatgg
    37021 taatttcgta aatgataaca ctcttactgt tacaataaaa cgtcttagag aaaaattaaa
    37081 aaatccacct tgtataaaaa cattaagagg cataggatat agaatggagg acaactagtg
    37141 aaaactccaa gaaatatcaa cagtacagtt gtttttataa tattctgctt aattgtaact
    37201 tttttattga ctgtaattct aacaactata acttctttta atgaatacaa tgtactgtct
    37261 aaggctcttg gtgcatcata tgagtacaat cctaagtcta cagaaagtat actaaaatca
    37321 ctgaaaaatt ctagtgataa ggattttaaa acaggaaatg aaattttatc aaaacatgga
    37381 tattctaaaa gtacattttg gagtaaaaac tttttttatt ttctagtgat atcgtttggt
    37441 ataatttcaa caatggctac agttgtatat ataatcaaac atagaacaaa taagcaaaaa
    37501 ctgagtagaa taaacaatct tactcaatac ttagaagaag tgaatttagg aaaagagtct
    37561 gtacttttac gatgtgaaga tgaattttct caccttgaag atgagatata taaaacagtt
    37621 ggggaacttc gttgttcaaa agaatttgct ttaaaagaaa gacaaactct ttcagataat
    37681 cttgcagata ttgctcatca acttaagact ccaattacct ctatgtcact tatggcacaa
    37741 ttactttcag aaaattgtcc agatgaagaa atagattata ttaacagact tacaaatcaa
    37801 atctcaagac ttgagagact agtttcatct ttacttacat tatcaaaatt ggatgcaagt
    37861 actttaatat ttgaaagcaa acttatagat gtacattctc ttcttactta tgcaattgag
    37921 cctatagaag gttctttaag agaaaaacat cagacattta ctatcgaggc ttctccttcg
    37981 gtagaatttg aaatcgatat taattggact ttagaagctc ttttaaatat tcttaaaaat
    38041 tgtagtgagc atatagaaga tggtggatat atagttgctt attatagtca aaatcctcta
    38101 tatgttgaga ttatcataga agataatggt aaggggtttg ctcaggaaga acttccatat
    38161 atttttaata gattttatcg tggtaaaaat gctagtaagg acagtattgg tatagggctt
    38221 gctctatcaa agtctattat agaacgtcaa aatggtacta tacatgcaga aaattgccat
    38281 aatggtggtg caagattcat aattaaattt tacacataaa atgctggatt ataggtaaaa
    38341 tacctataat ccagctatat ctatattcta tgttatctat tgttttagta atatacttct
    38401 atttacattt aaggttttat taaacaaaca acttaactat ccctatactt gtaagtagtc
    38461 ttaaatcgaa acctttaaat aagttcaaat agattttgtt tatattgttt cattttttat
    38521 agattctact atattttcat tcttcaactg cttgtatcct gtcatatatg atgctattac
    38581 aataaaaagt atcaatatag taaaacctat tattgtagat ataggtgcaa atggtaaata
    38641 ctctataaaa tatatttcat ttatacgtag aaaagcatac actattccta tttgcacagg
    38701 aatactaagt agtaatggtg taattcctaa gaataaacct tccaaaataa gcatcttttt
    38761 tatgccttct ggagataatc caacagaacg caacatagca aactcttgtc gtctacttct
    38821 aatatttcct gacactgtag caagtacatt tgataatcca atcatagcca ataaacctgt
    38881 aataaagcct actattaaat tcatggtctt tattccacta gccttttgtt tttcactttc
    38941 taaaacatcc tcaatactat aatctcctga accatagtct ttattataaa tggactctaa
    39001 tttttctctt actctaggaa tgtcctcacg attatttact ttaaatactc ctatcagcct
    39061 atttgaacgt aacctactta cttcatcata atttttagat atttcctgca ccatagacat
    39121 tggaactatt tgcattaatg tatactttga actagtatct actattttag gaagtgtgct
    39181 tgtaatagct cccactttca tgttgtaagt ataatcccct ttatcttcgt catatacttt
    39241 ttcatttaat ttaatgttat ctcctattga aagatttaaa taatctatat atactttatt
    39301 tctacgtgta ctacgattaa tatcttcctc cttattatat acaattgagg ttggattttt
    39361 tgtatcataa aataactttg ggtctacaga aatttgccta caatattctg taaaactctt
    39421 atcatcaagc ccaattatat ttgaaattat acgaaacttg ccatcacgtt ctataggaga
    39481 gtacttttta gatgaagcta tatttttaaa tcctccattt ttcgcaagtt cttttgaagc
    39541 atctttttca gtcaaccaag tggaagcaga cattttttga taatatagtg aactttttac
    39601 accttctgta ttatctaatt tttcaatgaa agcagactct acaggttcac tattttccaa
    39661 ataaacttct atatctcttt ggtccttata attatcactt ccataaacag cttttgctcc
    39721 ttcttgattt gcaattatat gcaaaaaaca tgtaagtaat aaaaaagata atgttaaaga
    39781 tattgttgca gtacgataag attttttacg agcacgtagt gcgtttgatg caagttctcc
    39841 ttctattcca aatatctttc ctaatgaata tttatgcgac tttttgattt taacactatc
    39901 tccttgtcgt attgcttcta taggagatat ctttgatact tttcgtgctg gtataagtgc
    39961 agaaatccag actgttacta ttgtaagtaa aactgctggc agaaaagcag gaataccata
    40021 agtaaatacc acttctggaa catcagtatg ataattaact gaattaacat aaactataag
    40081 cctattacac aataaccatc ctaaaaataa acctattggt aatggtataa ttgtcagtaa
    40141 aaagccttca aacactacag accttttaat ttgttttggt gatgcaccaa cactagataa
    40201 tatccctaac tgagtaagtc tagcatttgc agacagtgaa aacgcgttgt aaatcaccat
    40261 tacaaacacg gctactgtaa aaattgctat tgtaagatac ataataggag ttgaaaattt
    40321 tgatatacta ctcatagatg ctttctgttc tggtgaaaag actaacatct ttaaaagata
    40381 attactattg tatttaagat tgtattttcc atattcatta gtcttccatc ccaatgattt
    40441 agcaagtttt ggaagttcct tatacgtgtc tcttatattt ttaaatcgca agtacacagt
    40501 tatactatca ttaggtttta tacttgtttt atcaagatat ccaagagctg tatatgcagg
    40561 tattactgat gaagtagaaa catctacctt tcctactatt gtcaatgtag cctctgaaat
    40621 ttttttaaaa ctttcccctt tcgattttgg ggctatgggt tcaagaggct ttccatttag
    40681 gattctatct cctattggga gagtaatttt atcaccaatt tttacacttg gattattctc
    40741 aaaatattgt tttgataatg caatttcatt agcattattt ggtcgacgac cctctattat
    40801 agtatccttt tctggcatag aatcccaata ctctgatgta gcatttctat aaattatata
    40861 atctcttttc tcatcattaa ttttgcctac ataccattgt ccttttacca ttacatcatc
    40921 aactgaagaa aaattttcaa ttaatggtaa gtcacttcca taagtatagt caaacaattc
    40981 accatgccag ttaccttctt tctcaattga aagttttata aaatctgtcc acatggtata
    41041 caacagtcca cacaaagaag acatcatggt tgtagtaagt aatatagcta acattatagc
    41101 tatactacta cgtttattgc gtcgtacaaa gtctaaggtg tattcttgaa gaatattcat
    41161 ttcttcacca ccttttcaga gacaatcact ccatcttcca tagttacaat acgatttgcc
    41221 tctagtgcta ttttctcatc atgagtaata agaagtattg tctgattaaa tcgtttattt
    41281 gataagttta acaagtctac aatttcttct gaattttttc tatcaagatt accagttggc
    41341 tcatctgcta ataaaatagc tggtctatag attaaacttc tagctataga taccctttgt
    41401 tgttgtccac ctgaaagttg acttggaaga tggtttaatc tatcagataa tcccaatata
    41461 gatacaatct cagagaatct atcctcatcc acctttcttt tatcaagtaa catgggtaat
    41521 aatatatttt ttctaacatc aagggtaggt ataagattat aaaattgata aataagacct
    41581 acttttctac gtctaaaaac tgcaagagct tcttccttta aacttgatat ttctgtatct
    41641 tcaacataaa tctttccaga tgtaggtcta tctactcccc caagcagatg taacaatgta
    41701 gatttgccag aaccagatgc tcctacaatg gatacaaaat cacctttttg aactgataaa
    41761 tttacattat taagggctgt cactctggtt tgatttgaac catatatttt tgtgagattt
    41821 tcacatttta atatttccat atacaatcat ctcctttatg gttaaatttt agcaacctaa
    41881 aatgacatta tagtgacatg aatacaaata taaattacta ttaaaaatat tgtttagttt
    41941 ttgcacatta tttaaaatta taatataaaa caaaaactat gcaatatatt ttatttatac
    42001 ttttaatata ttacatagtc tttaaaaggt attaacttta aatctatagg tattcaattt
    42061 aataatcaat agcaagtatt ttatgtacta aaggagtttt gctctatata gactcaattt
    42121 agtaaaatta tttaataaat attacagact ataggtaaat aatatttaca aataaaatta
    42181 agtttattcc cttacactat aatatttctt aattatatta attgcaattt cctttacctt
    42241 tggccctgta atttctttat tggaatcatc tgatttaata gcaaaataat aggtgtcacc
    42301 ttcacgctct agcataccaa caaaccatgc atccacacgt ttattttttt catcaaatcc
    42361 tgttccagtt tttccatata catttatgtt tttatcattt acatctattt tcataatatc
    42421 tcttaaaata ttaatatgct cttttttaaa gtttgtatct ccctcaaata tttttgccat
    42481 tgtttgcact tgttcttttg gagatatttg taatgaagat tctaaccaaa atccatttaa
    42541 atgtcccttt ccatttttta aatcgccttc ccattcgcta atatcgcaat tcccatactt
    42601 taaatcatct aaaatatttt ggacagattt agcatcaact ttatctatca attttttgta
    42661 gtaccaaaca caagactcct taaatgcctc ttctaaacta agatttttat tccaattttt
    42721 atttggatac tctgtaccat catatcccat aactgattct tttgagttta ttaccccttt
    42781 ttctaaacca attaaagttg aaactatttt aaaagtagaa catggtgacc ttcttgtttc
    42841 aattaattct ttgttatata tattatattc tttattttta gtattataaa aaatagctcc
    42901 tccactaata ccttcaaaac aatcactata gtcaaccata ttaatttttt cttttttgtt
    42961 ttcaactttg gatttattta attcagagtt tatatgattc ttatcatgtt tttgttttgt
    43021 gttgttatgc tttcttccta cataatatac tcccatagct acaacaacta gaagaataac
    43081 tatccaaata aaattatttt ttcttttcat actttatacc atctcctcta cataagttta
    43141 tagttcacct ttaaaataat atacattatt tgtaatatac tccaatctag gagcttgaat
    43201 acttctattt ataaaatcta actttggttt aacatgtttt aaatttttaa aaatcacaat
    43261 accatcaata gattgtaatt cagctccaaa gaaaaaatag actaaatttc tattcccaga
    43321 aattttaact acatctaaat ttctgtttag ttttttcatt ttttttatta cttctttaga
    43381 aaatatcttc tccaattcat ttttatcaga ttgaatataa aagacagatt cagagcttaa
    43441 ctttttttca tcataaactt tcaaaatagc tttagctact acactataat ctttttcata
    43501 aagtttaaat ctaaaacttt cacttggact aggaataaat atagtaccta tacttataaa
    43561 gatactaaat atacatccaa tcatttttct tttatttaaa tcttttttat agtaaagctt
    43621 aatcatatgt acacaaatcc atataaatgc aattagcatc aatggtattg caaataaacc
    43681 tataaatagt agcattactc ctcccctaca tattatattt ccacacaaaa ataaaaaatc
    43741 acttacaata aatagagtta aagggataac tatatctctt atattttctt tacctaatat
    43801 aattatgttg attgaggcta tgatgaatat actcaatata actattagta tcattatgtc
    43861 ctcctttcag tttgtgaggt aattatttat tctttattta aaacttacta ttgtaatatt
    43921 taaatattac aatagtaagt tttaaatgtc aagtcgtttt aattgtataa ttatctttgt
    43981 acttatcaaa ttacgagtat ctattatata cttttttatc tattatcaac tatcatttat
    44041 tcagattgta tgggattggt taaatttaga aataccttct ataacatagc agaatatatc
    44101 aagaaagtag attttaattt tattataata tggttacata atataattgc tttactaaaa
    44161 tgtactcaga aaggatttaa cattcatgtc aaatattata ataaaaggac ttacacaaaa
    44221 taacctaaaa aatatatcat ttaaaattcc taaaaataaa attgttgttt ttactggagt
    44281 ttctggttct ggaaaatcca gtatcgtatt tgatacaatt gcagcagaat cacaaaggca
    44341 gatgaatgaa acatattctt catttatcag aaataggcta cctaaatata gaaaacctca
    44401 ggtggagctg attgataatt taactgcttc tgtaatcgta gaccaaactc ctcttggtgg
    44461 caatgcacgt tctacagttg gcactataag tgatttgtat tcatcattaa gattattatt
    44521 ttctagaatt ggagaaccct acataggaac aacttcatat ttttctttta atgacccaaa
    44581 tggtatgtgt aaaaattgtt ctgggattgg tagagttaaa gtaatcaata ttgaatctat
    44641 tataaatcct gaaaattcat ggaatacagg atgtataaat gactctttat ttaaacctaa
    44701 ttcatggtac tggaagcagt atgcagagtc tggacttttt gatttagata aacctataaa
    44761 agattattct tttgaagaat ataatttatt gctttatggt tcaaaaaata aagatggaaa
    44821 acaagaaaat ccaaaaatag aaggtatttt taacaaatac aatcaaacat atctaaatcg
    44881 agatattagc aatatgagca aacacacaaa agaaaaatca gaaagactta taacagataa
    44941 ggaatgtcct gtatgtcatg gaaaaagatt aaataaagaa actcttaact gtaatatttt
    45001 aggatattcg attgcagata tgtgcaatat ggaacttact gacctttatg atttattgtt
    45061 acaaataaaa gataaaagaa ctgaaactgt aataaagact cttactgatg gtttaaaaag
    45121 aatgattgat attggtctcc cttacctaca tctaaataga gaatcatcat ctctatctgg
    45181 aggagaagct caaagattaa aacttgtacg ctatatgggg agcagtctca caggtatgac
    45241 ttatattttc gatgaaccta gtgctgatat gcatccacga gatgtacatc gtatgaatca
    45301 gctattaaaa aaacttaaag atagaggaaa tactgtcctt gtagtagagc atgataaaga
    45361 tgttatctcc atagcagatg aagttataga tattggccca agtgctggta cccagggtgg
    45421 acaggttgta ttccaaggct cttatgataa attactttta gcaaacactc ttacttcaaa
    45481 tgcaatgaat ctatcattac ctataaaaac tgactctcgt catccaaaag gtacccttcc
    45541 aattagagat gcttgcataa ataatctaaa acatattgat gtagatttac cagttggaat
    45601 tatgactgtc gttactggag tagcaggttc tggcaagagt actttaatct ctcgtgtttt
    45661 tgcacaaaaa tacgaaaaag atgttattaa aatcgaccaa agcccagtta cagctacaaa
    45721 tcgttctatg cctgctacag ttcttggttt ctttgatgag ataagaaaag tatttgctaa
    45781 agaaaataat gttgaagaag gtttattcag ctttaattca aagggagctt gtcctgtttg
    45841 tgatggtaaa ggagtacttg ttacagagct tgtattcatg gaccctatta ttaatacatg
    45901 tgaagcttgc aaaggtacta gatatagtga agaagttttg tcaaaattat ataaaggtaa
    45961 atgtatagtt gatgtactat ctatgacagt agatgaatct cttgaatttt ttacagaaaa
    46021 gaagctatgt aaaatcttac aaacaatgaa agatgttggt ttaccttata tgaccttagg
    46081 tcaaccactt agcacactat ctggaggaga acgtcaacga attaagttag ctaaaaacct
    46141 caacaaaaaa ggtactatat atattttaga tgaaccgact acagggcttc atggttctga
    46201 tattgaaaag cttatgttga attttgagca tatagttgat aaaggtaata ctgtaattat
    46261 aattgaacat aatttggatg tattgaaaca agcagactgg gtaattgata ttggtcctga
    46321 tggtggcaaa aacggtggtc aggtcgtatt tgaaggtaca ccactagaaa tgtttgaaag
    46381 aggttgcact ataacatcag atttccttag aaaatcaata aatatataga taatataata
    46441 ctaatattaa aaaattaaga actattacat atatattact actttgtttt atttcataaa
    46501 tttaaatttt aactttattt taaaagaaat taacattata aaagctataa atcacaaaat
    46561 tttataaaat ttcaaatgta atttatagct ttcatttttt ataaatttat aggtattatt
    46621 ttttgttgat ttattgatga atctttgtcc caatttatat ttacgataat aaatgcatat
    46681 aagatataat ctacatgctt ataagttgag ttaatgtacc aacatatgtt aacttaagtt
    46741 tgtgcatagc tcgtgtacag gcaatatata acaaactgtg gtcataatca ctataatatg
    46801 ttttattatt tactgaaggt acaataactt catcaaactc taaacctttt gacattttaa
    46861 tagaagttat ggatactcct tttgtaaagc tagaactttc agaagatatt aagtgaacac
    46921 tatattcttc tcttaacgca tcatatacag ctttagcgtc attatctgtc tttaatataa
    46981 taccaagagt cgcattatca ctctttttaa attcttcaat ttctattttt atcttattta
    47041 tttcatcttg ctcgttatta cattttaata aagctggttc ttcaccatgt cgttcaatag
    47101 gctctaatga agatatgtct tgaatctttt tggcgaaatt aataatctca aaagtagaac
    47161 ggtaactctt gttcaacata actaattctc catcattata tagctgtttc atatcatcta
    47221 atgtatgagt atgattagga ttaaccaatt gtccaaaatc tccaagaata gtctttttac
    47281 acttaaaaag taagtttatt acagcatatt gaataggtgt ataatcctgc atttcatcaa
    47341 taacaatatg ccttataatc ttatcttctt gtataccttc atatgcagca tgaatatata
    47401 taaatgggta tacatctgac cattcaagtg ttttcttttc taccatcaca aacatgtttg
    47461 atatattcat ttgtttaaag aaatccttat atagtgtaag agtatttttt attgtcaaca
    47521 ttccattcaa acttttaagt atacttttta cctttggtaa atcttcttcc ataatattat
    47581 ctgattcaaa tttataatga atgtcttcag ctaccttctc taatctcttc ttaactggat
    47641 atctgttata tgcctcaaat ctactctgta tccagtcact tttagctgta aaacttccaa
    47701 aagtgtagtc ttttggaata aaaatcttat ttggcatttg ttttatataa tcatcaataa
    47761 gttttacaaa atcaagtgta gatttaaaac gcactctttc agaccattta gcatcattta
    47821 tttctaatgg gtctttctca ctttcaaaat taataactct atctaattgt acctctgcta
    47881 tattttcaaa acttaattca cataatggct cttctccaag ctcaggaagg acattggaaa
    47941 tatagtctcc aaagacttta ttaggtgata ggataattac attatttgct gatattttat
    48001 ctttaaatcg ataaagaaga aaagcaattc tgtgtaatgc tatagatgtt ttcccagaac
    48061 cagctacccc ttgaataatc agtgtatcag ctttatcatt tctaataatt tgattttgtt
    48121 ccttttgtat tgttgaaatg attgacttca ttttttcatc tgaagtgtga ctaagttctt
    48181 tttgaagaat atcatcttgt atattaatgg aactttctag tgcatattct aattttccat
    48241 ttttaatttt aaattgtcgt tttcttgtta tttctccatc cacccatcct attggagcat
    48301 catatccagc ttttccgatt tcataatcat aaaacatact ggcaattgga gaacgccagt
    48361 caagtattat aagctcatct tcataatcaa atgcaaatct accaatataa tacttagatt
    48421 catcatccat atctttcagc ctaaaatcta ttctagcaaa gtatggagaa tctttgattt
    48481 tattaatctt acctcgaact tttaccataa aagccccata gttatctatt tgttttagtc
    48541 cttgttcatt ttgaaacatt tcatgtgggt ctatttcacc acgatttttt accatataca
    48601 ttttagcgtc catataatcc ttatcaagct tgtcaacaag attttcagct ttcttaaaag
    48661 cattgtctag cttgttattt atctctatta gatgtgcaat ctcatctgga aaaaaagtta
    48721 ataactctgc atcatattca cacatattat gtttagaatt agatgcaata atatcgcaat
    48781 ttactacttg tttattttca gacatttaaa tcctcctttg ttaattaagt acttacactg
    48841 aatcattata cttaattgtg ttttggagtt tttaatcatt cttgctattt aacttaaagg
    48901 aagaataaat ttttgagtag gatatccaaa ttccacaagc aattctgctt ctgcaaagcc
    48961 caacttcttt atcatatctc tatgtcctgt atcagctttg tcaccctctc gaaaggtagt
    49021 aattgaaata tctgtatcta tcaagaaatc ttcaataact ttcttcaaaa acacttgtgc
    49081 aatgtctgaa ttacgatact gtggatgtat tccaaaaaaa tcaatacttc tagtttctct
    49141 attaaacacc atatttgcaa tagcgacatt attaagtttt aatattaaag ctctttcttc
    49201 taaaatatac tgttctaatt gatatatata ttcttcctct tgcaaattgg gaaatccatc
    49261 tatgactaat ctcactaaat tcatccataa tggtatgtca gacatacttg caagtttaat
    49321 ttctttttcc aactctagta cattctttaa aaataggtta tcttttttca aaacaaatct
    49381 tagctgcaaa ggataaaatt cttgttcttt cctatattta tttggagatt ttttatacat
    49441 agctttaaat atagaagtga atgcctgttg actttcatat ccagctatca atgcaatttc
    49501 aataattggt ttctttgaaa ataccaataa ttttgctgct tctgtcaact ttctccgctt
    49561 tatgtaatca tgcattgtta gaccaacaga agttgtgaaa gttctatgca ggtgatattt
    49621 tgagtaatga acagcattag caactatatc taaatccagc ttttctgata aatgctcctc
    49681 tatatagtca atagcagtta tgacattaat tactttgtaa gacattgcag cttccctcct
    49741 tttatccatg caacattata tcaattatta cttagttata tttaatgaat cttgctattt
    49801 tataaacaaa tttgttgttt aagttttcaa ttcataaatt taatatatta ctttttactt
    49861 tctgattaaa gactctaatc ctttaatttt caataacttt tcatttagta aatctaaaaa
    49921 gttatttatt attttcttct tattagattc cttttagatg ccttaattaa atgataaata
    49981 tttatattat acgactaaaa acagcttttt acaattattt aatatgatta caaacttacc
    50041 ctatcttaaa gtttaatggt gtcctgttat gaatcttttt attttaattt aagctcttca
    50101 tcagtttatt ttatatattg atgtatttga ttccatacaa aaaagagtgc ttcatgaact
    50161 aaaaagttca tttttaaaca ctctctttta tgtaaataaa tttctattct attttgaaat
    50221 attataattt gacttataat ctattaatac caaaaataat aaattgtacg tctaagaata
    50281 gattctaatt agttgctcag tagtaaaatc tatttttaac taatcctgct ttgtatgttg
    50341 aacatattct ataattgtac catctggatg tctcaatgtc atattatatc ctgtaggaac
    50401 ttttttctta tctcttacta caactgctcc attatccaat agataacttc tccattcatc
    50461 aacagaatca accataaaag tagattttgt ttctataaat ggtttaagag catcatcaga
    50521 accagataat agtaaaacat ttcctatttg cgctaattcc aacccaactt ctttatagga
    50581 aaaacgcaaa gaacattttt cttttaaaag attctcataa aaaggtatgg ctttttctat
    50641 atcttgaata taaaaacgtg ttaatatatc atatattttc atattttccc cctatatatc
    50701 tatataatat tacctctaaa ttataccact ctacaaatta tataacaata aattaagcat
    50761 agccttttga gcatcttaag tagaccttaa caatatattg gggttacatt agaatacata
    50821 aattaaatca ccttgatatt atttaggata aaatttatgt agtagcagta aatgttcttc
    50881 taattatcaa ctaacaaacg ataatcttta actttctata taatgggtaa catcattttc
    50941 gtaagatatt cactagctgg acgattgata tcatttaaat actggtaata tatatcgcca
    51001 tgaagtttat atccattgct atttgcccat gaaaataagt cttctaaagt agggtcttgt
    51061 aattcataag gtcctaaatc aattgcagtt attattttct gtgcaggaac aatcctttgt
    51121 agaatctcat ttttcccatc tatataagtg gctacaggaa accctacttc aacatccaat
    51181 tttgctaaat ccatgttatg aaaacataca atcggtgctc ctgaagataa aattcctctc
    51241 tcctccagat atttagaaat tttttcaaaa ctttgttttg aaaactctga aaactctacc
    51301 ataaagtcaa ttgtttttcg tattgccaaa aaacagtact cagattgttc agctattgtt
    51361 atattggata ttctagtcat tttattcctc cattacttta ttttcatttc taatcttttt
    51421 ataccaaatt atacgaaaat tcactgtgta actaattatt tcatatgaat ataaaacata
    51481 acctccttcc atttcttata tcgaaagtat agcaaaaata atctcatcat tcttgtcaca
    51541 cagtgctctt ataatcagaa catacttaaa agacttgcct aatttttagg caagtctaaa
    51601 agaaatcttt ttctataaaa aatttataca aacaattaaa agatcaaaat atagactaat
    51661 ataaaactat aaatttacta atctgaacct cccatggcta aagtcacaag attactgatt
    51721 tatagaattt cgcacactaa aatatgtctt actaattccc cacaggctac ccccctagtt
    51781 gctacgttct tacataagtt atttattatc aaacatcaaa atttaaacaa gtttcaggtt
    51841 catcttctat tcttgctatt ttaaacttac atgcaattaa tactaaagat actattggat
    51901 ttataatatt taataaagcg tatggaccat atgttagtgc agatacacct aatgttgctg
    51961 ttatatacgc cccgcatgta ttccatggta ctaatggaga agttaaagtt ccgctatctt
    52021 ctaaagctct cgacaacatc ttaggatgta tacctctctt tttatattcc ttattataca
    52081 ttcttcctgg tataactata gatagatatt gttcacctgc tattatattg gtaattgtac
    52141 aagttaccat agtgcataat actgttccaa atacaccctt tgctaatctt agtaaagaag
    52201 atgctactac ttcaagcata cctgtttttt ctaaaatacc tccaagagat aaagcgcata
    52261 ttgttaagga tacagtggac atcatattca taatcccacc tttagataat aaagcatcta
    52321 cctcctgtat ttgtgttgac gaaacatatc cattttgtgc tgcatctaat atagtattca
    52381 tagattctcc ttgaaaaact actgcaaaca atactcccaa tacagcacct actataagcc
    52441 ctggtatagc aggaacttta aatacaacca atccaattac tattgctgga gctaataata
    52501 atactggtga taaagtatta aatgtagaat ctaatgtaga cctaattaat tctatttgtt
    52561 ttatatctag tgcttgacct gaatacttca ttccaattac accataaatt actaaacaaa
    52621 ttaataatga tggtatagtc gaatatagca tatattttat atgtgtaaac aaatctgttc
    52681 ctgccattgc tggagctaag ttagtcgttt cagataaagg tgatagttta tctccaaagt
    52741 aagctccaga tattatagaa cctacgatta atccaattgg catacctaaa ctttgaccaa
    52801 ttcctaaaag agctactcct actgtaccca ttgtgctcca agatgaacct gtcgcaagag
    52861 atactattgc acagactaat gttgatgcta ctaaaaaaat atttggtgat aaaattttta
    52921 gtccccagta aatcatacat ggaactactc cacttactat ccaagttcct ataagtacgc
    52981 ctattataat tatgattaag attgcttgca ttgccatctt tatactatta aacatactta
    53041 attctaactc tttccattta aatccaagtc tatatacagc cacaagtcct gctactgctg
    53101 ctgctcctat tagtggtaca tgaggtgatg aaccatacac taatactcct agacttaaaa
    53161 ataatatcaa acaagtaatt ggtatcattg catcaaacag acttgctttt ctacattctc
    53221 gctctttcat aaaatagttt cctcctaatt atttaaacac tacactataa ttttttttga
    53281 aacatatttg cttgtactag atgacatgat acccccataa gttaataaaa attctaaatt
    53341 gtcacctaat ttataatcat attttgtgtt acttacatct agtatcatgt ggtctgaact
    53401 tgcccctaat atttttatat cagtgtctat tggaattaaa gagtcaatat ttatatcttg
    53461 tttacctata gctatgattg ccctttttaa gattccctta tcttcataaa caggtttatt
    53521 tctaaaggca tcaactccta tttctccaat aggaactgat ggtttttctt tacattcaac
    53581 tacttggcat attaatttaa atgcatcttg atatgttcca tttatatttt caccgtatgc
    53641 cgtttctcta ccaagtagaa tggactcgcc tattctcaaa ttagtaatac cttctggcat
    53701 attattattt atcaacaaat gaatcgaact tgaattacct ccagatacta tttctagatt
    53761 tattccaaat ttttcttcca ttctttttgc tatacttacc agtctgccta tattttccct
    53821 agatggtata atagctccat aacaggttaa gtttgtagct ataccaatta tttcaatatt
    53881 ttttaatctt actatctctc ttacattact aaaaaagtct tcttcataaa agtatccttc
    53941 tcgtaaatcg cctaagtcaa acataagaac tatcttatga ataatatttt tactttcaca
    54001 taattcattt aatttcttta ttgttcctaa ttctgagtta aaactaatat cgcaataatt
    54061 gataacttct tctaattcac ttaacattgg gattctaatc aatatcttag gtagatttat
    54121 atcttgtaaa ttttttaagt tttgtattct tgaatctgct atatggtcta ttccttcact
    54181 acatatttct tctactattt ctttttgtgc acaaaatgat ttagtaacaa aagatatctt
    54241 aatatttctt tcatgacaca tctgcgaaat taattttgca ttatgcttta acttttctat
    54301 atctatttct aacctaggat acataatctt tcctcctcaa aattcaaact ttttaacagg
    54361 agcttaagag atgcttcttc atatttttta gataaaacac ccatagatgc cataatatag
    54421 tcattatcta ttaatatctt tgttttttcc tttggaaata gtaattcatt atttttattg
    54481 tatttgagca tattatctaa tatttcaatt ctactaggga gcctagtaag tgctccccct
    54541 gtaccaacta tatatcttac ttctgttaaa tctttccctt ctgcaatttt gacttttcca
    54601 gttgttccat agatatttct tatttttcct gaatgtctta gcatagcttt aacaacagct
    54661 tcttttgtca acctctcaac aaataatatt tcttcttttg attttggtat tggaggataa
    54721 ttctctatta ctgcatcaat atctatagat agttcacttt gtaagttttc tttacctata
    54781 atttctacta tattcttcat atttacatat acacctaaat ccccctcaac acttctcttt
    54841 gcagtaggtt caggattaac caaaatttta ttaatatagt cacttccatc tgtaacagaa
    54901 tgtacatcag tagttgctcc acctacatcc agagttaata aatctccaat atttttatat
    54961 aaaagtttag aagcttccat tacagctcct ggggttggag taatattttc attaaccatt
    55021 tctttaatgt atttcattcc tggtgctgta gttatgtgtt cttcaaatac actttgaatg
    55081 attcttcttg taggttctat attcaataaa tctattttag ggtatacatt ttcagttata
    55141 taaagcttat aattagtatc ttcaaatatt aaccttattt cctcttgatt ttcaacatta
    55201 ccagcatata taactggtat gcctagattc atagaggcta tcatttctgc attataaata
    55261 gctgtatctc tttctccata atcgactcca ccagctatta aaattatgtt tgggtttatt
    55321 tcttttattt tatttaaatc agttctttta attctacctg atgttatttg acgaataaca
    55381 gctccagccc ctaaagctgc ttctttagct gcttttactg tcatatcata gactaatcca
    55441 tgaacagtca tttttaatcc accagctgca ctagaagttg caaacatatc attatacttt
    55501 atatcatcta cagataattt attagctaaa tctttaatag cacctgataa gccatttctt
    55561 acatcgccac cttcaaacac tgttgttgga gcttgacctt gacccaaaaa tataggattg
    55621 ttagtattaa tatcatggaa agcgtttacc actgtagtag tacttccaat ttcagctacc
    55681 aacacatcta tttttaaaga aactttgcta ttttccatta tttattactc atttctcttc
    55741 ttttttcaac taagaaagtg gctacatgta tgcctttgct gtttcttcca aatccagcat
    55801 ctatgccttg ttcaacagct atttcaggtg ttacttgtgt tcctccacac gcaatcatta
    55861 ctttatctct tatacctttt tctacacaat aatcgtgtaa ttttttcatg tttttatagt
    55921 gaatatcatc atgacttatt attgtagatg caagtattgc atctgcattc agttcaatcg
    55981 ctgcatctac caatttttct acaggtacag aagtccctag atagtggcat tctatgccat
    56041 atttttcaat acctccatgt tttatatcta ttatttctct taaaccaact gaatgttcat
    56101 cttctccaac cgtagctgaa actattttca taggtttttc ttctatatct gctcttattt
    56161 cttcatcagt tagtacctta ggttcttctg gtattactaa attgtttaaa tctatatcaa
    56221 acggaactct tcctttcact tctattctag tcccttcaga ttcatgcata acttctctac
    56281 ttatgacctc aatttcttgt aagttcattt ttttgacaaa ttccaaagct gcaaactctg
    56341 ctgttctttt atcagtagga agcatcattg ttatcattac aattccatct gcacaccatt
    56401 ccatttcagg cttaatttta gttccatttc tgtactcata tgattctttt agtctatttt
    56461 ctacattatc aaaatcgtca agctcatcaa tatatattat tttgtctgga ttttcaaatg
    56521 tacatccatc tattaacatt gatggattat ctatagcatt ttcatcatat tgagctacat
    56581 tattgtatcc aaagtgagca gttacaggtg ctaaataatc ttcttctctt tcataaacag
    56641 taccttcacc aactccacct tttatttttc tagatattcc atcaccattt ctttctggat
    56701 aatttccaga atcaacaaaa aatccttgtt ccacagattc aaaatatcca ccaacttcag
    56761 atatttcttc catatataat acagctcttt ctttaagttc tcttgctttg tctcttaatt
    56821 caccgacatc tttaagttct atcatatcca taagcccatc cataccaact aaagcttgct
    56881 ttgctgtatc acatgcttct atattgtata tatgccaagg tacatttcta ccttcatcag
    56941 gtgttatagt tgattgtatg tcagctctag ttaatactga tgttaataag tttaatacat
    57001 gagtaactgt tgcttctcta gttgatgatt ccatatattt agtattcatt tgagctctca
    57061 tcttataatc actaaataac tctctaagtg caacagcgta aggtaagtct atttttaaac
    57121 atggtgctgg aggtgctgtt ggtggaactg ttgataagca tatattattt ttatctatac
    57181 ctattttttc tgagaatata gagtttaaag cgtgttgaac cataagttca ggcattacct
    57241 tccatgcttc tctagcagta gcattagcat tatgtgctcc atcaatttga gctatattgg
    57301 caaaagccat tattttcttt gcctcacaag catctacaaa agaccttacc atgtttatat
    57361 tcctatacag aacattatat tgtgggtctt gatgtgctcc attgactcct tcctcagcaa
    57421 acattactgc tacttcagga ccagcaacac cacttacata tgaatgataa ttaataggtc
    57481 taccaacttc ttcttctata aaatcaagag ccttcctttg agctcttact tgttttcttg
    57541 ttattggaac tccacctata ccttgtggag ttccttctat aagcccatca aaatgtgatt
    57601 gtccagcagt tctgataacc attagatggt cagctccatg atgagctgcc attctcattc
    57661 ttcttatatc atcctcaaat ctaccagaag ctatttcagt agtaataact ggacttggtt
    57721 gagggtctat attattgaaa tacttagatg atggtagccc tacactcttc tttaaaggtt
    57781 ttgtacagtc tttatattta aaaggtccca tttcaagatt ttccaagtgt tctctccaaa
    57841 cccaacctct tcgttttggt ttatatttat ccaaatcttt taatatatag tctatatcca
    57901 attttttatt ttcctttaac atgattctac cccttctcta aataaacatg taacttcatc
    57961 ccaatattca cccttaacta ataacaaacc tgcttctcta accgttatat ttttagattt
    58021 agccaattta taaactacat gacctgctcc tttacctata agacctcttt ccataacccc
    58081 ttctaaaata ggttttactt caagagaaga aaatcccatt ctcaacaaga cagacctttc
    58141 tattgatggt gttgtattct ttttaccaag ttctatcatt ggttctacta tctgggtagc
    58201 taaactccaa aacctttctt ttaactcatc atcactcagt tcttgaagat gttttcttct
    58261 aacttcaaaa tcatcctctc tttttttcat gaacattcct ccattcgtat tgctttaatc
    58321 gaattttctg aatttttatt ttatattaaa ttaaaaaaca ataattacta taaattattt
    58381 aatacatcaa caacaaaatc tcttgaactt tttacttctt ccattaaaaa ttctatatct
    58441 cgattactta gcttatcaat attatcaatg tgattattag atatacaatt ttttataaat
    58501 gactttctta ttttattcat atcaatatca acacatttca ataattctgg tctttctggt
    58561 aatattaagt ttactcctgc aatttcttct cttggatttc caaattttat atctattcca
    58621 ttttctcttg caaaggtaag ttgtggacat atatgtttac ctgcacccgt atattctgtt
    58681 tcttgtacca ctataacttt atcttcatct aactcttgag ctaaagagaa tgctgctgct
    58741 aaagatgtat ttcctgctgg acctctttct ataccttcta gctgtgccaa taattcagtt
    58801 gtataaaaaa cttctccttg ttttactaat acatatctat ccatatatct aagtggtcta
    58861 gctgcagacc taggtacatc tgacctatca ggccatgtac agtatggtat cccaaaacct
    58921 gtatgtcctg ttgtaaatga ttttttatta aattgattat cactagccat gtgtaatcct
    58981 tttaaatcta cacttgctcc tactacttta gtattaatag aaccagcttt tatcaatcct
    59041 cttgcagttc cagtaagatt accaccacct gcatttgtac aaacaactat atcagggtct
    59101 tttttatact tttctctaaa ttggatagct aactcataac ctaaagtttc tacacctgca
    59161 attccaaatg gtgaatataa tgatgcgtta aaatagcctg tttcttctaa taaaactaag
    59221 aacgtataaa ataactctgg tccaacagtt aactgaacaa cttctgctcc atatgcctca
    59281 cattttcgcg ctttttctat aatttcaggt tgacctacac cattagaatc ataacattct
    59341 tgaactatta tacattttaa tccctgcatt gccgcttgtg atgctacagc tgcaccatag
    59401 ttaccactgg tagctgctat tacaccttta tatcccattt gtttggcatg atatactgca
    59461 gtagctgctc ttcttgcttt aaaactacca gatgcattca ttgcttcatc ttttacaaat
    59521 attctagctc ctttaccttc tttagcacat tttctagcta atttagtcaa atttttaagc
    59581 tctattaaag gagtatttcc aacagcatac tgtgattgaa ttgcttcaat atcttgtaat
    59641 gtatatcctg tttcactcat cattttctca taatcaaacc ctattccctc ttgttcaaaa
    59701 gaagaataat ccaatccgat tgcatttttc attatttcgt tatttcttcc cataacagct
    59761 tgataactca tatctttcat tgatgttgaa ttattcatta tatacacctc caaataatat
    59821 ttctttagct tggattccta tttggagtaa ctctggtata catttaccat aatcatgagt
    59881 ataatatgga tttattttaa gtaaattacc ttttacaagt ctgcctgtaa ttgttttaac
    59941 ttctactaag tcgcctatag aagcatcact ttgtataaaa cctttaaccc acatttctaa
    60001 ggatactttc ttagtatcct ctggaacttg tggagctctt tcttctggag tcaatactat
    60061 attgtgtata ataacccaat cattaatttt agcatccatt ttttcatccc cttattaatt
    60121 gactattgcc ttactaatta atttactgtt attttaaatt aaacattatt ttaccaatta
    60181 gctaactgtt atcttactaa ttagctagtt gctatcttac taattagcct ttgattcttc
    60241 ttccaattca acttctatct gatttcttat atctcccatt attgctctag gtactggtat
    60301 atccaacata gttttaagac ctggtctagc atttattatt aatggaatag agtttactat
    60361 cattgcataa gtacctactc ctccaggtat ttcaggattt atttgtaaat caatgtttgg
    60421 tatacctttt attgatacat agtctcctgt tttaatacct tctgcttctg gtattatctg
    60481 ttgtggatgc tccatttcaa ttaaaacttc tccatttaca tatccatatc cacattgtct
    60541 acaaccagca acatttccag ccaatgcctc tccgtactta gattttctat ctactgtagt
    60601 cattattggc tcttttgttt gttctatctt atctaatttc caacctaatc catcagctat
    60661 catatttatt gattctacaa aacctacatg acctgctata gtcttatctt ctacaccttt
    60721 tataaattct tcccttgtta ctccaacacc ttgttccacc ataacagact ttccaaatgg
    60781 agataaatca tttactctct tagcttttat actagtaact tcttcacaag tacctgaaag
    60841 cgccaatact agtaaatcta atacaaatcc tggatttatt cctgttccaa gtatacttac
    60901 tccattttcc tttgcaactt catccatttt tttagctaaa tctgcatcat cagcttgtgg
    60961 atatgccatt tgttctgctg ttgatataac atttattttt ctatttaata agaaaattat
    61021 tttatcaaaa gcctttttag taaatgaatc agttgctaac aaaacaacat ctacactttt
    61081 ttctctaaaa acttcttcat aatttttatt gataataact tctggtcttt ctcctctttc
    61141 aattcctaaa acatcataca tacttttccc tgaagtactt ctactacaaa cagatactat
    61201 ttctatacct tctttcttta gaatcatatt agccatacct attcccatag ctccaaatcc
    61261 ccatattcct actcttactt ttctcatata tacaccctcc taaaaattta tatattctca
    61321 ataattagtt aaagcataaa tcgtgccaac tttaaaatta aagtaaatat ttattggaac
    61381 gttgaaacta taattatttt attatgtatt ttcataaata aaaaataata tttcttatga
    61441 gaaataaaaa aaagagcaaa atattttgct cttttataat aattttgctc ctctattttg
    61501 cttttttatt ttactttgat tttgtttttt tatcttgctt atttataata ttttgatatt
    61561 atattttttt attttatact gtaaattttg cctattcata cctaaaattg atgcagcttt
    61621 agttatattg taagatgcct tttctaatga ttcatatata tacttttctt ctatctcact
    61681 gataatctta ctaagtgttt tgtcctccaa atcgtttaaa gaataattgt tactctcttt
    61741 attctcttta agattgtaat agtcgtttag attaatcata cttgtttcta tttgtacctc
    61801 atcttccatc atactcatag tacaataaat tatgttttct agctctctta tgttaccttg
    61861 ccaatcgtaa ttttttaaaa ttttaatagc ttcatctgaa attcctacca cttttttatt
    61921 taacttttta ttatactttg aaataaattt tttgcacaat agaggtatgt cctcttttct
    61981 atctctaaga ggaggaattt ttatatgaat tatgttaagc ctataatata aatcttttcg
    62041 cattttatgc tcgtttaaaa ttacctttgg actttcattt gtcgttgcaa taattcttac
    62101 atctataggt atatccttag ttcctccaac ccttcttaca taaccttctt gtaaaaccct
    62161 taatagttta gcctgtaaca taataggcat ggaatttatc tcatccaata acaatgtccc
    62221 tttgttagct tgttcaaata agcctggcct atctattgct cctgtaaatc ctcccttgct
    62281 agttccaaaa agaatacctt cgaatagtga ttccggcaaa gctgcacaat tttgtgctat
    62341 aaatggatag tttctcctat tacttccata gtgaatggac tggctaaata actctttacc
    62401 cgttccagtt tcaccgtata taaatactga agcatcagac ttgcaagctt tcttagattt
    62461 agctattgct tctttaatca aattactttc ccctaaaata tcatcaaatt cataaccctt
    62521 tttttgtcta ctactaactt tattgactaa atttttttta taatttctgt ttagtaaatt
    62581 ttctatcgtt gtcatattct ttgatatttc aagtgcccct acaaactcgc ctttaatatc
    62641 aattggtatt gtagtattaa ttgctgttat ctcttttcca tttttatcca gatatttctg
    62701 aatattgtct ttgataactt cccttttttc caaaacttct aatagtgtac tcctgtttat
    62761 tttcattttg ttgactatat caaaaaatga attggctaaa atatcgtgtc tgttcatttt
    62821 ttccattttt tgtacagaat tattgtagat tatagttttc ccgtctttat taacaaaatg
    62881 taccccttca tcaatatttt ccaatatttc attcattatt ttaaaaaata tctcttggtt
    62941 caactatatc accccagtac ctaaatatat aaaaacccaa aaaattaata aaatgttgct
    63001 attgtattta tcttatcata tatttatgat attttttatg tacattatat taatatattt
    63061 ttaagtatat ttaaaatttt atttatatat ctttcattat ggttatatac aatatttgaa
    63121 ttgtcattaa atatgccaat agttttatat attattgatt ttattaaaaa aagagatata
    63181 caaactaata agttgtaatc tctcaaatat aaaaaaacaa taaattagct cattggattt
    63241 tttagtccat aatataatta tagattattc accaaacaat ctatagaaat tgtggtatta
    63301 atgtttaaat aaccaacttt ttctaaaata acctttatag gaatatatga gttcataagt
    63361 aaagatagcg aaataagaaa ccagtttggt atgtaaaatc tagattttta attaaattat
    63421 caagattata tattatagta tcaaaaatag aaaattaaaa ttaaattttt tataataaat
    63481 tgtatacatt ataaattata ttaaattttt aatttaagta atagtatatg taatctttag
    63541 tcatcttctt accagttttt tatccacttt tctaatgaag ttattttttc atatgttaat
    63601 tcctcttgaa ataatgatac taaaagactt tttataaaat tataacttaa aagtttatgt
    63661 atttttttga tatgaattta tagtacttat cttctttaat tgagattgtg tatatttaac
    63721 ttaaatatta catcaataat tccatgcaat caaatcaatt atttacatat ttttttagaa
    63781 caataataag tatatattca caaaattttg tgttaatatt tttaatttgt gatataataa
    63841 aagcaaggaa acatatttta cttaactttg agtgatgttt ccttcaacaa attattttga
    63901 agatttactt ttctggaact ttatattaag ttcccagcca ctcttagttg gtcgctcaga
    63961 gtggctcttt aatttatcgt aaatgtaact ggctataaca ccagttataa tactcatcat
    64021 tagattttcc atagttttca cctcctctca taagaaagtg aagaaacttc catggaaaca
    64081 ccactcatag ctttttcaaa tatttattcc ttgccatatt aattatatca taaatattgg
    64141 aaacataaaa ttttaatact tatcgtcttt attattattt tttataatta ataattttct
    64201 ttttaataat acataatata aatttatatt tcttcaataa aaaagacaat cttaattaat
    64261 tgtctttttt aatatatatt tggctaatac attattttac acaaacatta caagggtcta
    64321 ttttaccttg tgacttagcc tgttttaatg ttactttatt tattgtttta cttcttttta
    64381 gtgtagaaca attttttgtt agatgatatg attttccatt aggagttaca tatactgtac
    64441 ttttatcagt taatccagga ttattagagc taggctcatt acttggtttg ttcgtattat
    64501 ttgaattagt atcttttaca atacctgtat ttgaatctcc aacattatta gttatattta
    64561 aacattgttt tataacaaca tcatcaatat ttccaatagc agttatttta cttgcatttt
    64621 ttaatatact cttattactt ccatttccaa ctaacactat aggtgttttt tgtgcaattg
    64681 tagaaccaac taaagaataa actaaatcag tcccacttgc tatgtaaaat tcttttgagc
    64741 cattataaaa tttatttatt atttgtttat ttgtatcgta tctatctact ccacctattc
    64801 ttgttgcttt agtttcattt attaacttat cactcatact gacttttcca ccaattgcat
    64861 aagtttctaa tccatctgta acaaaacttg tagtatttcc atcagttaat actattggag
    64921 atttatctct aactgctata gaagcaacac tcatagcatc tggttcgcct ttaaaagcat
    64981 tagttaatat tactttttta accgtactta ctcttcctat ttcttttgca actttatgac
    65041 ttgtatctat tctatcagtt ccacttattc tatttatgct tattttttta tcacttaata
    65101 ttttctgaac tgatgctcct atcgaatttt ttcctccaat tagatatact tcttttacct
    65161 tttctaatct ttttaatgtt tctgaaggga ttgtatcttt cttagttaac aatattgggg
    65221 catttttagc tcctgacaat ccacttgctg acaatccatc agataatcca ttttcagaat
    65281 taataagtat tgcaatatca taattttgtt tatctgctat taaacctgct gtttcatact
    65341 tatttgtacc ttttattgaa ttaatagaac taagagcgtt tgatgttgga caactagcaa
    65401 tcaataatga aacagacatc cctattgcca atagtgtttt gcttaatttc ataatgaaat
    65461 cctcctataa attttataat attacttaaa tattataatt ctacataaaa gaatattttc
    65521 ttttatgaaa ttagtttata tttcaaaatt ttgtcacttt ttaaatctat atactaaaaa
    65581 atagactatt tgtaacagtc tatttcttag tatatcaaat atttatttag gtttacgttt
    65641 ctttgtacta gtttttgtat atgatattcc agttccaggt atactcaatg taactgattt
    65701 tcttcctttt gaattaactg acactctagc acctttaaca ccagcactta tacctacact
    65761 cttcttacct aaatttaatt tgagtcctcc tcctagattt atgcttttcc taaagttaaa
    65821 tcccatagat ataaccttcc cttctatatt ttaaatattt atacttaaaa ttatatttgt
    65881 tatacacttg tcatcattgg tatatctagc atctatatct ttttacgttt tttcttctta
    65941 tatactactc cagcaactac agctgctgtt ccagctccaa ccccataagt agcatttcta
    66001 cttttctctt cttctctttt ttctaaacct tcatcatata caccttttaa cttagtttca
    66061 atagacttca tttcgtctgg tatactaaaa tcttcttcat tgtaaccttg attatataca
    66121 ctttcttttg ctttaggtaa cttaacctta ccattatcat atccttcttt aaaccaatta
    66181 gcatatttaa cattacctat agttgatgtg tcaaatcttt ctcctttgat agcactctca
    66241 aatccttgag tagtgtaatc attttttaat tgttcttgta tttcgtcata agcattatta
    66301 taagcatcta taaattcaga atctatgttt tcttcaaatg tcattttttc tttatcttta
    66361 ttgctatcct ctatcccttt aactttatat tcttctatct ttttagtctt atattcattg
    66421 tatccagttg aatatccggt atcataagca ttttttaaaa cttctttttc atatgtatta
    66481 ttagatttag cacctgtaag ccctaaatta tatccagtct ctttagccac cttttcttcc
    66541 tcttctaatt tagccttacc tttttcatat ccttctgagt actttgattc atatgtatca
    66601 ctataatctc cactataatt tgatgaacta taatttcctt tatacccatc ttcataccct
    66661 tgattatatc ctttttctcc aacagacctc ttttgctttt cttcattatt aaccgaagtt
    66721 gttgttccag aactgcttcc tcctccagta taaggacaac caccattatt atgtaaatga
    66781 gctggataac caccacaatg atagtgataa cttcctaatc cagatttatt tttattatca
    66841 cgatgacctc ctgatgaatc agttcttcct gaatgagcat acgaaaagct ccctacacta
    66901 atcatagtta tactcattgc aacagctatt aactttttct taaacataat ctatttcccc
    66961 ctaaaatatt ctatgatttt attatatcag tcaatatatt atgtttaaac cgttaaaatt
    67021 cgacaatgta aatatttgat gaattgtatt tgtaaataaa tcttttagca tatcttgaat
    67081 atctgtagtt gttttgacat catattcttc aataagtttt ttaatatttc gtttttttta
    67141 aacataaaaa gcgtgcactt tcctttgtat agtgatattt gatattttaa ttatcactac
    67201 tttagaagaa tacacacttt attttaaaaa ccctgatact atgttattag aaaatggtac
    67261 taatataaaa gatatccagc atatactcgg acatgctaaa acttcaacaa ctatggatac
    67321 atatttacat gtaactaata acatgagaaa ccagacggta aatatttttg aaatcattgt
    67381 agaataaatt tgccacccaa aaataattat ggtggcaaat aggtggcaaa tctactttta
    67441 agacacaata taaaagtctg aaaccctgtt attctctaat aagtttaact acagtctcac
    67501 aatgtggcgt atttgggaac atatccatac acttaaccat cttaatctca taaccatacc
    67561 ccttaaaatc aaccaaatca acaaccaaag acttaggatt acaagaaata taaacaatct
    67621 ccttagcacc aaatccacaa atatccctaa tagcatcctt atgaatgcct ggtctaggag
    67681 ggtcaacaat aatcaaatca ggcttgtcct ttaaatcctt aacaacctta gccacatccc
    67741 cagcaataaa ctcacaatta gtaagtccat tcaacttagc attctcatta gcagtaacaa
    67801 cagcttcctc aactatctca ataccataca ctttcttagc agcaccagcc ataacctgtc
    67861 caatagaccc agtaccacta tacaagtcaa atacaacttt atcattgtaa tctccaataa
    67921 aatccctagc aatactataa agaacctcag ctcccttagt attggtttgg aaaaacgaaa
    67981 atggtgaaat cttaaactta agacctaaaa tttcttcttg tatataatct cttccataca
    68041 atactcttaa ctcatcacat tggactgcat ctgctaaacc atcattaata gtatgaagta
    68101 cacctactaa ctcagctttt aaatcaatcc ctaaaagcat atctttaaac tcattcatat
    68161 caaaatcttg ttgagaagaa gttactatat taaccataat ctcattagta tgaatacctt
    68221 ttctaactac aagatgtctc aaatatcctt tgtgattcat tgttctataa taaggaagct
    68281 ttttttcatt gaaaaactct acactagaaa ctaatatctt tgagaagtct tcatcaacca
    68341 acatacactc ctcaacagtt tgtatatcta tatgctttcc ttttttatga agacctaatg
    68401 tcaaaggtcc attttttact tcatctccaa aagtatattc catcttattt ctataatatt
    68461 tgttttctgg acttccttct atccctaaaa actgaaatcc aaataaatct tgctttaaaa
    68521 ataaatccat aacttgtttt tcttttattt ctaattgttt ttcatatggc acagacaata
    68581 gtgtacatcc tccacactct ctaaagtgct tgcaagtttc ttcagtttca agtggtgagt
    68641 tctctaataa ttctatcatc ttaacttcag ctttcttact tctaactttt ttaactccag
    68701 ctctcacctt ttgaccactt attccaccct tcatatggat aactctatct ccaacttggc
    68761 ttaaagatgt accaccaaat tccattttat ctacttcaaa ttctataaca tcttttttct
    68821 tcacagacat tcctccaatt tactatagta tctttattat ctttcttcaa tcaattttac
    68881 ttcttcatct gttaactctc tatactcacc taactctaaa ctttcatcca attttaaatt
    68941 gcccatagac aatcttttta agtatactac ttttttgcct acgctttcaa acattctttt
    69001 tacttggtga aacttacctt catgtattgt aagctctatt tctgattcat catcactttt
    69061 taatatattt aactgtgatg gcatagtttt atatccgtca tcaagcacta caccttctaa
    69121 aaaagcttct acatcttctt cagtaactac tccatcaatt tttgcataat aagtcttagg
    69181 cacatgcttc ttaggagata aaactctatg agaaagcttt ccatcattag ttaaaactaa
    69241 taatccctct gtgtctttat ctaaccttcc aacaggaaat ggttcaaaag ctaagtatga
    69301 taaatcaatt aaatctaata ctgttgggtc atatttatct gtagttgctg atatatatcc
    69361 atcaggttta ttcatcatca aatatatata ttctctatat ataacttctt ctccattaaa
    69421 taatatctca tcattttcag tgtctacttg agttcctgga tttgaaactt cacttccatt
    69481 tactactaca gacccttgtt tacaatactt ctttatttca cttctacttc cataacctaa
    69541 atttgaaaga attttatcta tacgttgctt tttagccatt aaaaatgctc tccattctca
    69601 taatattttt ctttttcaaa tactgtaaat gctaaatcca tactttctac atctaaatta
    69661 tttcttatac tatcagttat tattcttgct actatatctt gtacttcttg tcctctatca
    69721 aaccaagcta cttcaacaaa aggatataca tctgctattt taccatttct tattgcaact
    69781 gactttatac attctatttc aaagtagtct cttggacatt ttacagcttc aactaaatca
    69841 tttatcattt tttcacttat tttacatata tcattttcat taattcctct tatttttatc
    69901 tgtggcatag tttatctcct ttattttaaa tttttagtga attatcatcc acttaattcc
    69961 cttcgataac gtttgaagtg gtaacttctt ggtcaagaca actattgtta tcagtatctc
    70021 caaactaata aggtagttcc tacccttata gttagcatta tatagctagt tttcctaaat
    70081 tgtttatatt ctttattatt ttatttaatc ctattgtctt ctatttaaca ttatacttgt
    70141 aatttatagt tattacaatt tactatatac tttttttgat ttaacgttat aatataagtg
    70201 atgggtaaat tttaaaagtt aataggagga gtttaaaatg gcattaatta ctacaaaaga
    70261 aatgtttaaa aaagcttacg aaggtggatt tgctataggt gcatttaaca taagtgactt
    70321 agaacaatta caaggtgttt taaaagctgc taaagctaaa aattcttatg ttatgataca
    70381 agcttctatg tcagctgtta aatatgctgg acctcataca ttagttgaaa tggttaaggc
    70441 tgcttctgat gaaataggtg tagatgtagc tcttcactta gaccatggtc caaatatgga
    70501 tgctattaaa acttgtattg atgctggttt ctcttcagtt atgatagatg gttctcattt
    70561 tgactttgaa gaaaatgtta gaataactaa agaagctgtt gaatatgcac actctaaagg
    70621 tgttgttgtt gaagcagaac ttggtgttct agctggaaca gaagatgatg ttacttctga
    70681 tgttcacaag tatactcaac cagctgaggc agttgagttc gttgaaagaa caggtgttga
    70741 ttcattagca atagctattg gaacttctca tggtgctttc aaattcaaag gagaagctaa
    70801 attaagattc gatatactag aagaaatcca aagcaaatta ccaggtttcc caatagttct
    70861 tcatggtgca tctgctgttg accaaaacgc tgttgctaca tgtaatgaat ttggtggaaa
    70921 tatagctggt gctaaaggtg tacctgtaga tatgttaaga aaagcatctt ctatggctgt
    70981 ttgtaaaata aacatggata ctgacttaag actagctatg actgctgcta tcagaaaatt
    71041 cttagctgaa aatccaaaag aatttgaccc aagaaaatac attggtgctg gtagagatgc
    71101 tatacaagct gtagttgaaa gcaagataga tgatgtttta ggttctgcta actctataaa
    71161 ctaatataac ttttaaatat ttataaaaga aaagagatga cttaaagtaa ttaaatttat
    71221 ttttaagcca tctcttttaa gttgtatcaa ttatgtatct tataatattt taattatatt
    71281 gtctttttaa actgacagct aaacgtgaat atgtccactc tttatctttc tatggatggt
    71341 agaaggatat atacctataa cttcagcagc ctttgttatt gaaccatact tatttatagc
    71401 cttacttatc attatttggt ccactatttt atatgcatca ttaagattca taattccatt
    71461 taccactatt ggtgataaat catctgtttc attatcaatc atatctaaat ttatcagcat
    71521 gttaaattca tcttctccaa ttacattttt agctgataat actacaaatc tttcaatgat
    71581 gttttttaat tctcttatgt ttcctggcca agaatattct tctaataaat caataacttt
    71641 aggcgaaact tctacttctc tattgtactt ttcattgtaa agttttaaga aataatttac
    71701 taatggtact atatcctctt ttctttctct aagaggaggt atttttactg gaataacact
    71761 taatctatag tacaaatctt gtctaaattt aaggttattt ctaaggtctt catgagaaat
    71821 attagtagca cttatatatc taacatctat ttttataggc ttactaccac ctattctagt
    71881 aatagtattt tcttgtataa ccctaagtaa ttttttttgc atctgcattg gtaactcacc
    71941 tatctcatcc aagaaaatag ttccaccatt cgcctcttca aaaagtccct ttttaccttt
    72001 tttcttagct ccagtaaaag aaccttcttc atatccaaaa aactctgact ctaataattc
    72061 atttggtata gctccacagt ttatagctat aaaaggtttg tctctccttg aactatactt
    72121 atatattgtt cttgctatta tttcttttcc tacacctgat tctccattta taaatataga
    72181 agaatctgag gctgcagctc tcttaacaac tttttttata ttgtccataa tcttactttg
    72241 acttatatac tctgtgtctt ctgatatatc actatatttt atctgagatt caagcttaat
    72301 aacccttgaa atatctctcc ctgttagtac tcctcctgta agctttccct tagaatccca
    72361 tcttggaact gccgtatatg caataagctt cccatctggg taaacgatat ttctataaat
    72421 ctttttcttc actttaagca tgtttaatat tattggttct tcaactaatc cttgtctcac
    72481 aaggtctgtt atatttctac caagtacctc agttctttta aaaggtaata tctcatcact
    72541 gacagtgttc atcttttcaa ttaccccatc tttgttaaac acaacaacaa cttcatctat
    72601 atgctctatt atatcttcaa ttactttatc agatattaga gacttctcaa ataaataaac
    72661 tatattattt tcattattat tatctttcat attgtatata tgtgcagtca tccttaactc
    72721 tctgaaagct attttctttt tactatctgt cagtatttct gttttgtcaa aatttgaatc
    72781 taattcattt atatttctag gcttttttat atctagaaaa ctaaaaatac tatctattag
    72841 atgattacag tatattattt cgcctgattc tttacataaa atggctggat tttctacatg
    72901 ttctataagc cctattaaat tattatccat taatattcgc acctttcatt aagtaattta
    72961 ttgaactaca tacaaaattt attgtttgct tacaataaat accatcagca catataatca
    73021 actccttata atattcgtct tttcaagtag tttatttcat taaaacgtaa ctaagatata
    73081 attttaatga ttatagtttg ttaaaaattt cattttgctt ttaattgtat tttatcacat
    73141 atttagtaat tatttgtcta tttaatacaa tttaattaaa tttaagattt atttaaaaaa
    73201 acaaagataa tccttacaga atataactca caatttgtaa gcaatataca tataaggatt
    73261 atccagatta tcttgtatta taaaatttta ttcaaacaga ctttttaata actgacaaat
    73321 acacactagc aataacttat caaagggtta ataattatgt tactaactaa taagacttat
    73381 tcaatcagta atatttatat agtttgtatc tattaagctt ttatagcttc taataaatca
    73441 tcaacgctat ctaatttttc tataagcatc ggaactattt catgtaagtc tccaactact
    73501 ccatagtcag cgatttctaa aattggagct gctgggtttt tgtttatagc aattatgaaa
    73561 tctgatgatt gcatacctgc taaatgttgt attgctcctg atataccaca agctatatat
    73621 aggtttggtt taacagtagt tcctgtttga cctacttggt gagaatggtc tatccatcca
    73681 gcatcaacag ccgcacgaga agaaccaact actccaccta atttgtcagc taatttctta
    73741 agcatttcaa atccttctgg tccacctaat cctagaccac ctgatactat aacatttgca
    73801 tctgtaagag atactaaatc tttcttagtt ttaactgttt ctaaaacagt agttcttata
    73861 tcatcttgag ttattttgta gtctaatgct ataacttcac cagttcttgt ttcgtctttt
    73921 tcagctttat ccataacacc aggtctaact gtagacattt gaggtctatg gtttggacaa
    73981 atgattgtag ccattatgtt tccaccaaat gctggacgag tttgttttat tttcttatct
    74041 tctgggtcta tttctaactt agtacagtca gctgttaatc cagttccaac tcttgaagct
    74101 attctaggtg ctaagtctct acctatatga gttgctccga aaagcattat ttctggtttt
    74161 atttcatcta ttgcatcttt tattactttt gtatatgcat cagttgtata tttttctaaa
    74221 agagcatcat ctgcaacata aactttgtca gctccaaaag tgattaattc tttagctaat
    74281 ccatcaacat cttttcctaa taatattgca caaagttctg catctacttc tttagctaat
    74341 tttcttcctt ctcctaataa ttctataact actggagcta tttttccttc tctttgttct
    74401 gcaaatatcc atacgttttt ataagaactt aaatctttta tatcattcat agtttgtact
    74461 cctccaactt atataatgtg cttttgtttt agaccgatta ttattttact agctatttca
    74521 tcagctttac cttctaagat ttctcctttt cctcttggtt caggagtaaa tgatctaaat
    74581 actttagttg gtgatgcttt taaaccaact tcttctttat ttacatctaa atcatcaatt
    74641 gtccaaactt ttacatcatg tttatatgct tttactattt tatcaacaga catgtatcta
    74701 ggtgtattta actcttttac tgctgttaaa agtacaggtg tacttacttt tattaattcg
    74761 tatccatctt ctaattgtct ttgaactatt atatcttttc cttctatttt gaaatcttgt
    74821 acatatgtaa cttgaggaat gtctaatttc tctgcaattt gtggtccaac ttgtgcagta
    74881 tctccatcta ttgcttgtct tcctgcaaat attatgtcat agtcacctac tttagatatt
    74941 cccgctgcaa tagtatttga tgtagcccaa gtatcagctc ctccaaatgc tctatcactt
    75001 aataatattg catcatcagc acccatagct aaacactctc ttagcataaa gtctgcttga
    75061 ggaggtccca ttgttataac tgttatagtt acatcatcat gctcatcttt aatttttaaa
    75121 gcttcctcta atgcatttgc atcatctggg tttaatatac ttggaactcc atctcttata
    75181 agagtacctg tttctttatt tattcttact tcgttagtat ctggaacttg ttttacgcaa
    75241 actaatattt tcaaagtcta tacctccaat ttcattagat tatttattat tttaatacgt
    75301 ttgatgaaat taccattttt tgaacttctg atgttccttc gtatattgat acgattctag
    75361 catctctgta cattctttcg atttcataat cttttataaa tccatatcca ccgtgaagtt
    75421 gtaatgcttt ataagcaact tcatttgcaa tttctgatgc atagtattta gccatagcag
    75481 attcttgagc aactctcatt cctgcatctc tcttttgtgc tgcatcataa actaatcctc
    75541 tagctgcaca aacttttgtt tccatgtcag ctatagtaaa ttgagtattt tggaatttag
    75601 ctataggctt accaaattga actctttgtt ttgtatattt aacagcttca tctaaagcac
    75661 cttgagctat tcctagagct aaggcagcaa cacctattct accaacttct agagtaccca
    75721 ttgctatctt aaatccttga ccttcttttc caagtaagtt ttcttttgga actttaacgt
    75781 tttcaaatat taagtcagaa gtttcagttc ctcttatacc catcttatct tcatgagctc
    75841 ctgttgagaa accatcccat ttactttcta ctataaacgc tgatgttcct ctaagtcctt
    75901 tacttctatc tgtaactgct attactatag ctacatcaca gaatggtcca ttagttatga
    75961 aagtttttct accatttaat atatagtggt ctccaactaa ttctgctgtt gtttgttgtc
    76021 cacctgcatc agaaccagct cctggctcag ttaaaccaaa tgctcctatt aattcacctg
    76081 ttgctatacc ttttaagtat ttttgttttt gctcttcagt accattgtaa agtattggta
    76141 atgaagcaag agaagaacca gctgtaacaa aagtagctgt tgaagcacat cttctagcta
    76201 tttcttccat tactatagcg taagaaacat atcctgctcc cccaccacca tattcttctg
    76261 ggatattact gcttataaat tttgcatcag ctaatttttt gattaattcc ttaggcatta
    76321 cacctgtttt atccatttct gctggtaaag tatctaattc tttactaaca aaatctctta
    76381 ctgcttttct taaaagttct tgttctttgt tatataacat agcttcctcc aattttcata
    76441 ttttatagta aatttatttt aatgaactta cgctaaactc atcatctcag caaaagtttg
    76501 aatacgagtt ctggcttgtt cattattctg agtttgttgg tcgatttcaa catataaagt
    76561 aggtattcca ctatcttcta tatcttttct aactaaagga taatcgtatt cttctgggtc
    76621 acagaatttc atcatacaga agataacacc atctatatct ttctttttaa cttcatctac
    76681 tataagtgac ccacgttttt tcttagggtc ataagctaat gaacatcctt ctatgtttga
    76741 ccattgtctt gctaatctct ctaacgcatc atcacctgct ggtacatctg ttctgaattg
    76801 tcttgtttct tgtgctaagt cgtcagctac aactgatata ttgttgtctt ctaaaatgtc
    76861 taatatatct ttagaatcag ctaatatacc tgttaataaa actttctttc cagaacagac
    76921 ttcttctggc atagcattta attttgctat taaatctttc actagctcag tatgttcttc
    76981 ttttctcata aagaacccac tcttaattac taagcttctt attgatggtt ttatagtatt
    77041 agaatgttta taagctactt caacaaagtc tctcatagtt tttctatgtt cattgtaaac
    77101 ttctatactt tcatgaattt ttgcttcttc tatttcatat ccacaaattt cttcaagttc
    77161 tctttttacg cctttgtact cactgattaa gtattttaca ccagcttcaa gttttctatt
    77221 ttgtgggtgt actaatgata tatattttat atgaggtact gctgatttcc agttttgtcc
    77281 taaacaaatt agtgtatcac acatacctgg tataataact ccagataatt catcataagc
    77341 accttttaat ccatattcta aacatgattg cattattgaa catgcaaatg cagggaaata
    77401 ttgtttagct aaatctaatt ctgtttgtcc tccccatata ccaactggaa gcattccagc
    77461 tgcatgtata atttcttctg ggcaataaac tgggaaacaa cctatagctt ttttaccagt
    77521 ttcactttta tattttttta cagccgcatt tggattttca actacttctt tcattttaga
    77581 taaaatagct tccattatat ctcacctcta ttaagttttt ttctttcttc cattacttca
    77641 actaaacctt gaattcttgt ttcaaattga gcattagtga aagctctagg gtctgcttgg
    77701 tcaccatcaa atccagcata tggtaatcca gtttcttcag ctgctcttct ttgcatttca
    77761 tattgtatta aactcataag tttacagctt ctgttcatat gatagaatgc tccatcacat
    77821 ttaccctcta ctaaagaatc aactctatat tttgtcatac ggtctaggtt tacattgtta
    77881 aacatagtac tatatgctac tgccattcca tctaaatcat taacttcata ttgtaatgcc
    77941 caagcatgtg ggtaaacact acctgtcatg ttaactccaa atttagctaa tgttttcatc
    78001 ttgtatccta tatatggcca acaaggtata ccttccatca ttattctgta tttttcttcc
    78061 cctctgaaag aagatttacc agttttcatg ttgtcctcta attcttctat aagtaactta
    78121 aatgcttctg tagtttcttt tttacctcta gcacaaacta ttacagccat gtaagtaaat
    78181 aagtcaaatc cattcattgg agaaggagaa gaatctgctg gtaaactcat agaatacttc
    78241 catagtcttc cgttttcagc tgatattttc attacttctt caaacttctt agggtcaaat
    78301 ttctttcctg atataatttc tagttgtttt atagcttctt caaattgagc tttaatataa
    78361 tctattcttg attgagtaac ttcgtcttca ttattgaaag ttgtatcaat cattattaaa
    78421 ggtatatcta attctcttga aatattttca taccatttta taacttggtt acatatattg
    78481 ttacagcaaa gtaggaaatc tggagctggc atatccaaag cttcacatcc accattttct
    78541 aaaagaccaa aatttgttct tgcatatgca cataggtcaa tagaatatcc tttagattca
    78601 gctatttcac ataattctaa agaacctttt ttagctgcta ctccagctgc ttggttttct
    78661 ggatataata cgtttaagtc aaatacttct gctaactctt gaggaaatac tgatgttgac
    78721 caacctacag gtcttccttc ttctttagct ttaaatgcat ttgcatattg ttcagctaat
    78781 aaatcattaa ttactactct agcttctttt ttttcagaca ttttcatccc tctttttata
    78841 tatttttcac ttctttttgt gattcttttg cttcatcaaa agcatataac gctgctccta
    78901 aagcaccagt taattgaggt atatcaggta caataatttc tgtgttgatt tctcttgcca
    78961 tagctcttac aataccacta tttctagcaa ctccaccaac cataactaca tttctttgta
    79021 ctcctattct ttttactagg ctagaaactc tctttgctac tgaagtatga atacctgcca
    79081 ctatatcttc aatttttgca ttttcagata aatgtgatat aacctcagac tctgcaaata
    79141 ctgtacatgt actgcttatt gatacttcat tttgagaatt catagatata cttccgagtt
    79201 cagatacatc aacctctatt atttttgcca ttacatctaa aaatcttcct gtacctgcag
    79261 cacatttgtc attcataaga aagtttaata gtcttccatt attatctaat tttaatacct
    79321 ttgcatcttg accacctatg tcaataatgg ttcttgtctc tggaattatg aaatttaccc
    79381 ctctagcatg acagcttaat tcacttattt gcttatcagc atctgaatag ttcattcttc
    79441 catatcctgt aactacaact tttttaatat cttctcttgc aagacctgtc ttgccatata
    79501 atttttctaa aactcttgat ggtccagtag tcccagtacc agaggatatt gtttcagaag
    79561 ctacaatatc ttccccattc tttaagatta ctccctttga tgcagttgaa cctatatcta
    79621 atcccattgt gtacatcttt agcattctcc ttttaaaaaa tctagaatta ctaattaata
    79681 tcttacaact ttactatctt taaagttatt tattttctct tcatcgtagc ctaaagattt
    79741 taatacttct acagtatgtt gacctacttt tggtgctggt gtatattctt taattccttc
    79801 atttctaaac ataactggag tattaactaa gacacctgta tttccgctat cgtatgtttt
    79861 cttaaataag aagtcatttg cccaagcttg ttcgtcatct aataaatctt cacagctttg
    79921 aattttttca aatggtaagt ctgcttcttc taataaagct gaccactcgt ctaatgtttt
    79981 ttctaacata gcttctccaa ctatcttaac taaatcttca acatgattaa ccattgaatc
    80041 tatgttatta tatctatcgt cttctaatat atattctcta tttataacct tacagaattt
    80101 gcctaaccac ttgttgtatt gtattaaagc taattgaatc catcttccat ctttacattt
    80161 atatgtagtc attaatgggc tgtttggatt ttctcttgat aaaggcattt catttccgta
    80221 ttgtgctgtt gttatcattg ttcccattcc atatatagct gtatggaaaa gacttactgt
    80281 tactctctca cctttaccag tttgagcttt tttatgtaat gctgctaaac ttcctgctgc
    80341 tagtgctaga cctgcatagt ggtcaccaaa tcctgctgct gtatttgctg gagatgttcc
    80401 tttttccata acagattggc taactcctcc tcttgcgaag tatgcagtat agtcaaatcc
    80461 tggtttatct tttaaaggtc ctttttcacc atatcctaat atttgagaga atattaatcc
    80521 tggatactta tcttttattt ggtcataagc tatacccatt ttttctaatg cttgaactct
    80581 aacattagtt acaaatatgt ctgcttctga taataattta tgtaatattt ctactccttc
    80641 ttttgatttt acattaatac ttacaccctt tttatttcca ttttctaatt caaacatagg
    80701 gttttcatca tctgatgctg gagatttaaa tgttccaccc ataactctta ttccatcacc
    80761 ttctataggt tcaatcttaa taacctctgc accccagtca cctaacattt ttgcacaaca
    80821 tggtgctgcg atgaaacttg aaagttctac tactttaact ccttctaaaa gcataacgtt
    80881 ttcctcctta atagtatcaa ttataaaatt tcgattaaat cactcataaa atactttttt
    80941 ctgatattaa ctgtctgatg tcaaagttcc taatcttatc taaaataact taaaaattat
    81001 taaaattatt ttttattgtt ttattgtctt acacctatat tgttaagcat ttatcgtgcc
    81061 aactttatat ttaatcaaaa tatcgcttga tttgaatgtt ttttaacaat atgcaattga
    81121 ataatctttt tcatatcgtg gcatcttgcc actatccatt gcattttgct attctttcta
    81181 tgcttataaa agtttttttt atatattttt ttatgaaaaa gcttgacatt tcaaaaaaag
    81241 ttttcattgc taaactcaaa aacacatgtt atcattgtaa ttaatcagca agttagttaa
    81301 ctaatttcaa acttagataa ttttttaata atatttaatc taaaaaataa caatttcttt
    81361 gataaatttt agagtaatta ttacattaaa taaaaaatta ctaaatatca aaataacaca
    81421 gggaaaacaa tttcaaaact aaatttttaa ccttaaaaat tttgtataaa aaatataacc
    81481 ttatatgcta catattattt ctaaatgaaa aattaccata ataatttaat aattacagga
    81541 gggtattgat atgaaaatac tagtatttgg agcacgcgat tatgaagaac cagtaataaa
    81601 aaaatggtct gaagaacata aggatgttca agtggatatt tatcctgaaa acatgactga
    81661 agaaaatgta gttaaagcta aagggtatga tggtatatct atacaacaaa ctaactatat
    81721 agataatcct tatatttatg aaactttaaa agatgctggg gttaaagtta tagcttcaag
    81781 aactgcaggg gttgacatga tacattttga tttagttaat gaaaatggac ttatcgttac
    81841 aaacgttcct tcttattcac ctaatgcaat agctgaatta gctgttactc aagctatgaa
    81901 ccttttaaga aagactcctc tagtaaagaa aaaagtctgt gaaggtgatt accgttggat
    81961 agctgaactt cttggaacag aagttagatc tattacagtt ggtgttatag gtacaggaaa
    82021 aataggtgct acttctgcaa aattattcaa aggcctagga gctaatgtaa ttgcatttga
    82081 ccaatatcca aatagtgatt taaatgatat attaacttac aaagattctt tagaagacct
    82141 tctaaaagaa gctgacctta taacattaca tactccttta cttgaaggaa caaaacatat
    82201 gataaataaa gatactctag ctataatgaa ggatggagct tacatagtaa atactggccg
    82261 tggtggttta attaatacag gggatttaat agaagcacta gagtcaggaa aaattagagc
    82321 tgctgccctt gatacatttg aaactgaagg attgttctta aacaaaaaaa tgaatcctgg
    82381 agaattaact gacccagaaa taaataaact tctttctatg gaacaagtta tattcactca
    82441 tcaccttggt ttcttcacta gtacagcgat tgaaaatata gtttattcta gtttaagcag
    82501 tgctgtagaa gttataaaaa caggaactgc tactaataga gtaaattagt attttataaa
    82561 tatatttttt cattaattag ctattatcta acaaaatagc ctttaatttc ccaaatataa
    82621 gagagtcagc tcagtatata ttgagtagac tctcttatat tattttttat attaaacttg
    82681 tactcttctt attcatacca aattaaattt atattaactt attctaacta ttcctactct
    82741 atacatttta cctattttta cttttctaat tatatacatt tgaatgggta caatctgtat
    82801 tttacaaaaa aaacacctaa caaactatga aaattgtatg attaatatta atatatttat
    82861 aagaaaacat aacaattatg ttagctctgg atttttaggg agggagtata ttggaaaaaa
    82921 tgaataaagt tacttctaaa aaaactacct atattgttac ttcagcatta tttgcatcca
    82981 taatatgcct gacaatagca tatatattac atattccagt tggtggaaac aatggatatg
    83041 ttcatatagg agatgctttt atttatctag ctgcaactat tttgccaaca aactatgcta
    83101 tagctgcttc tgcaattggt gctggtctag ctgatttatc tacaggtgct gctatctggg
    83161 taataccaac tataatcata aaaccaatac ttgtattatt tttcacttct aaaagtgaca
    83221 agataataaa taagagaaat atagttgctt cggttgtagc aggtatagta ggattagttt
    83281 tatacatgtt tgctgaaggt ataattattg gaagttttac aagtgcattt gtaatgagct
    83341 tacttggctt attacagcca ataggaagtt ttattgtttt tataatctta ggtatggcac
    83401 ttgataaact tgattttaaa aaacgttatt ttaattaaga atttaaattt atggagggaa
    83461 aattatgaat atcttatata caattgaaaa tagtatctat gtaaatataa ctaatacatg
    83521 tccatgtagt tgtgtttttt gtataagaaa cgaaaaagat gaagttgcaa atagtggtag
    83581 tttatggctg gaacatgagc caagtgtaga tgaagtaaaa gaagccttca ataaatacaa
    83641 tttagacgac tatgatgaaa tcgtattttg tggatatggc gaaccattaa tgagaataaa
    83701 tgaattgata gaggtagcaa agtttataaa agaaaaaagt agcataaaga taagaataaa
    83761 tacaaatggt ctaagtgatt taatacataa caaaaaaaca gctattctgt taaaaaatgt
    83821 tatagatgca gtatcaataa gtcttaatgc cccaaataaa gaagcttata atagagttac
    83881 tcaaccaaag tttggagaaa aatcatttga ttatatgtta gattttgcaa aagattgcaa
    83941 aaaatatata aaagaagtag ctttttcagt agtagatgaa atatctccag aagaaataga
    84001 agaatctaaa caactggcaa aaaaacttga tataccatta agagttagac ataagaatta
    84061 gcaagtaaaa ttataaaaca ttaagaatca cctgaatggt atttcaggtg attcttcctc
    84121 ttgtattaac attttacaaa atagatttca taccacacta ggaatgtgta aatcatccaa
    84181 atctttctcc aattatcaga gtttccacta atgtagtcat taaaaatctc attaatctca
    84241 tctatgttaa agaatttatc tgctatctca ctattgaatt tatctcggat atccttatta
    84301 tattggtcat cagccatcca tatacgaatt ggcacaataa atcctaattt atttctaaaa
    84361 gcaatctctt ctggtaatgt ttttgatgca gctgtacgaa aggcaatttt attctctttt
    84421 cctttcactt tatattctga tggtattctg gatgcaatat caaatattct tgtatctgta
    84481 agaggcattc tgacttccaa tccaactgca gtactcattt tatctatatt aaaataaata
    84541 tctccttcca accatatttg aatatctaca tttgacatgt tagtaagtgt atctagttct
    84601 tctgtttctt cataaattcc ttttaccact tcaataggaa tcacatcagg attgtatttc
    84661 ttaagaattt ttcttttctc accctcattc ataatgtttg tatttccaat ataaaatgtc
    84721 ttcaaattct ctccataaca ctctgcctta tggtatatat tatatccacc aaaaaactca
    84781 tctgctcctt ctccagagta acagatattt gtgttttcag ctgctgcctt gcatccaata
    84841 gcaaaaacga tagcagatgc atctccagtt ggttgctcca tatggtacat tacataaggt
    84901 actgacgcaa aatactcttc aggtgtaatt atatatctcg aatttttaca cccaagaata
    84961 ttagctgtct gttgtgctaa ttttgattca tcaaaacgct cttcctcata accacatgaa
    85021 cctgtttttt ctatatctga cattgccaat atataagatg aatcaacacc tcctgatagg
    85081 aataactctg cagtttcatt ctctgatttt acctctggca taattttctg aagtgttgta
    85141 tgaatttcat ccgtccattc ctcaatagac ttgctgtggt caggatgaaa ttcaggtttc
    85201 caataacgac caatacatac tgttttattc tgatagacaa ggtaatgtcc tggcataagc
    85261 ttctttactc cacggaagaa tgtattttca cctgctacat atgtgaaaga catataaatc
    85321 tgtaacatgt cttcatttaa ctctttcaca aatcctggtt gctccataat cttacgaata
    85381 gatgaaccat agagaagctt cccattttca gtctcataat aatagaaagg ttttactcca
    85441 aactggtctc ttaggcagaa gagtttcttt tccacagtat cccataatgc aaaggcaaac
    85501 attccatgca tgtgatttgc catatcatat ccccatgtct tatatgcttc cactaaaatt
    85561 gctcgttcac gctcatctct acataatgaa gaatcgattc caagttcttc acaaagaact
    85621 ttccagtttc gaatatgtcc attgtattct agaattttta tcatatatgt gtcttttcgt
    85681 gttaaatact tttcttctaa atttatcata tgtgtatcct ttcgtattaa aacatttaac
    85741 ttctaaattt attaaatgtt tatatatatt tattcactta taatcactga aaaatcgact
    85801 tttttcaaag taaattcttt ttgaattagt actaatctgc tctttattaa tggcataaat
    85861 atgattatca agtattatca gtgttataac attgaatttt ttattcttca taaatattgc
    85921 cctctttata ttaccaacta aatataatat atcttatgtt acttacatat tctttaagaa
    85981 attctgaaga ttttataaag ttttttgtat tataattaat taaaaataaa attttagtta
    86041 taaagcatat tttccattaa acaaaaaata gttaaaataa attcataacc acataaactt
    86101 attttaacta tttgcatatt ttaattataa atattaactt aaatttttaa caggatacac
    86161 tcataaaata aacataatga acaacaaaat aatatgtctc agtttcttta tatactttac
    86221 cttctttcaa ctttctacca tgtagacgta taagataata ttagtaattc actctattgc
    86281 ttaactcgtg cgatatggac aaccaagaaa gctatttcct catttgttaa cttttttcca
    86341 tatttctttt ctaaaaaatc tctaactttt aatgcaatta acatttcttt tggatttgac
    86401 cttttcattt gattaaataa taaatcatca ccactgctta acatactatc tgaaaaaaat
    86461 ctttccacaa aaaattttat atgtgttata aatctcatat aatgcatact ctttttatct
    86521 aaggttctat tcaaagaaaa aacaaaaata ttaattattt ctccaattac tttggcatac
    86581 ttaatcgtat catatgaatt tccatctgaa gccatagcat ttgcaaaatg gaaagcaatg
    86641 ttagctgctt cttcctctgg taattgaatg cccaatctct cctctaccat ataaattgca
    86701 accattccaa ccttaaactc atttggataa taatttttta tttcccaaaa tactcgattt
    86761 gtaattttta ttcctttacg catcctttca attgcaaagt taaaatggtc tgctaatatt
    86821 aagtataagt ttttattaaa agatgagttc aataactttt ctgcctctac tattatttcc
    86881 tgtgttatct ttaaaatgtc gacaggaata tcatccatta attctaaaaa ttgttttgat
    86941 tttgtatttt caacagggac aaacatttga ttatcattgg aaccacaaat gtattctcct
    87001 gtttttttac catatccaat tcctttccct agcaaaataa attcattatc ctttgtgtca
    87061 tgaactaaaa caacgctcga gttcaaaact ttctttatta tgtagttcat tttatttgct
    87121 caccttctat tggtcattta aaatctatac tattattttc aattactttt ttataccaat
    87181 aaaaactatc tttcttatat cgattatatg tcccctttcc ataatcatca gcatccacat
    87241 aaatatatcc ataacgtttt gacatttgtt tcgttgattc actgaccaaa tcaatacaac
    87301 cccatgaagt gtatccccaa agttcaacgc catcttcgat aatcgcatct aacatacatt
    87361 taaagtgttc ttttaaataa ttaattctat attggtcatg aactttttta tcttcagtta
    87421 aaatatcttt ggctcccaat ccattttcaa ctataaataa aggctttctg tatctatcat
    87481 ataattcaat caaagatata cgtagaccta ttgaatcaat ttgccaaccc cattcactca
    87541 tttctaaata aggatttttt acagctaata acgtattccc aggtgtaata tctaatccag
    87601 ttgtatcagc tgcctcacaa gaagacatat agtaagagaa tgaaataaaa tctactggat
    87661 actttttcat aatttcatca tcatgttctt cttttactat ttgaatgtta ttatttttaa
    87721 aatacgacag taaatatact ggatactcac caaaaacctg cgtatcacta tatgcataaa
    87781 tacttctcat tttttgttga gttgccaaaa catcttctgg tctacatgtg tatggataat
    87841 acgttaattt tgttaacata caccctactt ttgaatttgg aataatttca tgacaaattt
    87901 ttgttgcaag ggcactagct acaaattgat gatgcatagc ttgaaaaata acttcctcaa
    87961 agtttttatc cttaaaacgg tctcgaacta aaccaccagt agtgtacgga tgacgaatca
    88021 tagaatcaac ttcattaaat gtaagccaat atttcacttt gtttttatat ctttcacaga
    88081 tagtttctac atacctaaca aacatattga taacttgtcg tgaataccat ccatcatagt
    88141 ttaaaacgat atttaatggt ggttcataat gtgacatagt aacaagtggt tcaattccat
    88201 aacttatcaa ttcatcaaat acatcatcat aaaactgtaa accttcttca tttggctctt
    88261 tatcatctcc atttggaaaa atacgagacc aagcaatact cattcgatat gtcttaaatc
    88321 ccatttctac cattagagca atatcttctt tatagtgatg ataaaaatca ctaccatgac
    88381 gttttggata atttacttca tcttcaggat gtgctaatcc ttcttctata tcttttgttg
    88441 tgatttcatt attagattta taatctttca catctgcatc aaagtgtgcc tttgctacat
    88501 ctgatacaga ccaccctttc ccacctaaat tccaaccacc ttcaaattga ttagcagctg
    88561 tagctcctcc ccaaagaaat ccttctggaa actttctcat atttatattc ctccctttac
    88621 atcaaacaag atacttcctt tttttacatt gccataagac tggtttaaca ctttataagc
    88681 ataatctgct ccattattgt ttacaatcat aacagttgaa tctaaattag catgtgagat
    88741 tttgtctaaa tcaaattgaa ttaataaatc tccttctttt acattatcgc ctgtcttaac
    88801 aaatgtttta aatccatctc cattcatact tacagtattt attccaatat gaatcaaaat
    88861 ctcagcccca ttttttgttc ttaaaccaat tgcatgtttt gtttcaaata acatcacaac
    88921 ttctgaatca caaggtgcgt ataaatttcc attggttggt ataattgcaa ctccatctcc
    88981 caaagtctta cttgcaaata gttcatcatt aaccttactt aaatctatta cttttccttc
    89041 tactggagtt actaagatat ttacttcttt ttcttcttct agctcttctt caacaacatc
    89101 tccaattgat gactctactg tatttgtatc ttccttccaa ataatcagtg taataataaa
    89161 cgagcctaat attgcaataa caaaaccaat acttgcaaaa atcaaattgt ttccattgtt
    89221 tgggtcaata aacatactca tactggcaaa ccctggtcca acaattacaa atccttttac
    89281 tgcaaataat cctaaaaatg taccagaaat tgcacttgag aatacaacac ctaacattgc
    89341 tcttttatgt tgtaaagtaa taccatataa agctggctct gtaattccca tcaaggcaga
    89401 aattcctgca gataatgctg tttgttttaa tgtttcatct tttgttcgca aggctactgc
    89461 aaaacaagca ccactttcag aaatattgtg ggctaatgaa gatgtcatat ataaagcttc
    89521 ataacccaac tttccaattg tattaattga ataaggtatt agtgctttgt gcattcctgt
    89581 tgcaaccata aatggaagaa aagcagcaag taatcctaca actaagaatc ccattttgtt
    89641 atataagaat aaaataatgg ttgtaaaaat tgtaccaacg ttatatccta aaggacctaa
    89701 aatagttaga gtaattggaa cagtaattgc caaagacatc ataggaacaa agaaagttcg
    89761 aattggtttt ggtgaatact tgttaaaaat tttctccatt gttgccaaga aagacacaca
    89821 taagatagct gggaaaacct gtgcattata ggcaatgttt ggaattgtaa atccaaatag
    89881 ttcgacacct tcacttaaag cagttgttgt tgctggaagc aataagtatc ctacagcggc
    89941 aatagctact aaacgattac atttcaatac attggcagta gttacagcta ccataagagg
    90001 taggaaatag aatgttgcat ctgaaatagc aactaataat gtatatatag tagaatctga
    90061 ttttaaaata ttaaacattg ctaataacat caacagtgat tttaaaatac cagctcctgc
    90121 aatagcaaaa atcagtggtt gaaaaatatt aataataaat tctataaatc tttttcctaa
    90181 gtttattttt tcttcagttt ttacagtact atcatttgta tctaaagggc aaacttttaa
    90241 aatttcatca tacacatcaa caacactatt cccaatgaca acttgaaatt gtgccccatt
    90301 aactatactc ataacacctt gtactttttt taaagcatcc tgattgactt tacttctatc
    90361 aatcaactta aagcgtagtc tagttgaaca gtgttctaaa gctaaaatat tttttgaacc
    90421 accaacttgt tcaataatgt caatggcagt ttttttataa ttcatcttgt aatctccttc
    90481 tccataattt tttatgaatg gccattcaag atgcaaaaaa ggcagaacct atataaacac
    90541 cttgaaaaat caaagcaata tattcgatcc tgcctgcatt accagtaaca tgtcttctat
    90601 ttatactatt ttgtattatt atattaacat ttgcctaaaa gaattgtcaa tactttttta
    90661 aattttctga tactaactaa tagcaccttt ataattcatt ttttatgtca attaaagtaa
    90721 cagtagccac ccaccaatta gtatcaaaat tgaacctggt attttttctt ttatattttc
    90781 tttgaatata aaatgagcaa gtattaaagt tattatcata gatacttgag aaaatggctc
    90841 tgctatacta agttctagat tatttaaagc aattaataat gctaaataag aatatccatt
    90901 aatagcacca cttaaaattg aaagcccctt tttattagta aaaatctcac aaattatttt
    90961 ttgtttcttt ttaaatgcta aaaagataaa taaatttaaa cctacgaaaa aatacagtat
    91021 agttgaatat aatataggag atacttgtac aaaaaaagcc ttatccaata ctcttcctac
    91081 tgactgcaaa aatatgtata aaaacattaa tctacatggt aaattgttaa aaattacaga
    91141 aacattcttt aaaaaagagc ttactttttt taatataaac actccaccaa tcataattat
    91201 gattcctgca acttttgcta aacttaaacc ttcacctaaa aatataactg ataaaagcag
    91261 taaaaacaat gaatttaaac tatttattgg agtaacaagt gaaacttccc cagttgctaa
    91321 agacgttaca tacgctactg aaccaattga atagactaaa ctacttatat aacatggtat
    91381 taaaaacgac caatcactaa ctctatccat tatgctaaat ggaagtaaac atactccccc
    91441 tataaagaaa aatagaaatg atgaagctat atttttataa atatctcctt cttcatcacc
    91501 taataatctt acaactactc tttcaaaagc taatagcact actctaatta ataatgcaaa
    91561 ataagataat atcatttttg acctcgctta aaaattaatc cgacttattg ttatattaac
    91621 tgtataagac taccatatag gtaagtcttt tggatttttt aatattttat gtttaaatac
    91681 aggtacatta agtttttcac ctagtttacg gcattgctct ttataggtac cttttaattt
    91741 atcatgaaaa actatacaat caattcctcc ttcaatacta tttatacact tttctagttt
    91801 ctcaaatccc gattcatcat catacattcc acttacaatc cattgatttg gcaatacatg
    91861 tccaattgat atgttatatt ctttattttt tataatatct gagaaagatt tctcaaaatg
    91921 tacccctcca acacataaca aagtcttcaa aggttcatca caatcaaata ctctaattaa
    91981 tgattttgcc aatacctgta ttgctatact attattaaaa ctatcactac tacttcctat
    92041 ctcaatatcc aacataggta cagaatattc tgtaattaat ttagattctt caccatatgt
    92101 tgttccagac cagtgagttg cttctgttaa tgtagtaaat tcatcaagta gattttcatt
    92161 ttttatatcc tcaatagcat tgattagatt tttaaagtat cttggatttg aatttccaaa
    92221 ttctcctgtt ggaacatctc caattgtatg agctgttagg atatgttctg gagcattttc
    92281 tccctcatgc caatttacaa ctcctgcaaa atcataatct ctaaaatgtc tatttaaaat
    92341 tggaagataa tatttataat tatgacttat tacatctttt gtttttacaa aatgaaataa
    92401 gttattgttt ttatccttaa actctaatac aaaattatca tcaataacaa tatcagtttg
    92461 atttaaatcc attatttctt cacaacattt tatcacatta ctggctactg ggtctttctt
    92521 taaatcactg caaaagaaaa aaactgcttt tttattattc atccataaat cacactccta
    92581 taacttaaat ataatatatc ttcataccta aaatcatcta aatatcactc taattccatt
    92641 aaattattta tatataatat actaccatac tcattttagc tatacctttg cctgagtttc
    92701 tatatatatg tgatacatca gctttaaatc ttatagaatt tccactagat acaatgtaat
    92761 cttctccatt tattttaatg gttacttcgc cactaaaaac agttataaac tcttgtgttc
    92821 ctggaagttc agcatttgaa tctaaatttc caccttcttc tatttcaatc ataaatatct
    92881 caaatcttct tttggagtca aatggaaata ttggataact tatatacttt ccattatctt
    92941 caataaaatg gtctatatca cttttttgaa tcaattctat gtcactttcc tgcctctcca
    93001 tcaatgatgt aaatgagatt tttagcccat tagttatttt cttcaaagta gatatagtag
    93061 gatttacctc acacttttca atttgagata gcatactctt acttacacca ctaagttgtg
    93121 caatcttgtc taaactaaga tgtttttctt tccttatctt ttttaaattt tcagcaatta
    93181 tttcatttaa actttgcata aataccccct aatacatact aatataagat aaattatttt
    93241 gattattaaa taaacttagt aatttaatag aaacttttta tccattataa tgtacattat
    93301 gtttaatata cattactttt tttagaatgt aaatagtttt ctgaaatttt gtgaaaatga
    93361 gcaaataaaa aactagtaac ctatattttt acaaggttac tagcttttat tataataata
    93421 tttcatttta actataaaac ttagatgcac ctataagctg tctcttagaa acaatcttag
    93481 ctaggtttgc taatgaggaa atttttatat ctttaaaaga aactaaaaat acaaacttaa
    93541 aatctgtaaa ttcttgattt atattgtata tatcaaaata acatctcaaa ttatcaaata
    93601 agtaattatc ctgtaagtct gcttctatct catcagtagc atcttttaaa tacgctctta
    93661 catcttcaaa taaaacactg aaataagact catctatttc ttcacctaac tcttccaata
    93721 tttcttctat atctaaatca tccatatcaa aagaatttcc tgtcaactgg caatcaaata
    93781 ccaatatatt ttcttgattt atagtatttg atatatcttg tacatattcg aagtctggac
    93841 gtaattctaa aatgtctttt atttcactgc tctttacatg gatttttcct tttctatttt
    93901 caatttttaa atctatcata tgctccccct ttcaatctac aaatctttaa ataccttgtt
    93961 ttataatctt ttcaatatct atccaattac taactctaac tatattttga tgtttaacat
    94021 ctttattata gttagtatcc agaagtatta ctttaacacc atcatcagct agttgcactg
    94081 agtttaaagg attatcttct ataaatatgt cacaactcag ttctcttgcc ttttcaactt
    94141 tataatcact tcctaataag taaacatcta tatctgaaaa tccttgtctc gatagccaat
    94201 ttttagttac atcagttaaa cactcatgtc tagccgttac aaaagataaa ttatgtcctt
    94261 tagataatgt gctaattacc tctgtagcac cctctacaat ctttgcttca tcatatgagt
    94321 gtatatactt attattaaac tccgcataca catctcttat tcccgaacca tacaattctt
    94381 cccaattatg tgttatacac tctgcttcag ttatattttt attaaagata tcatttaggt
    94441 atggaagaaa atgataaggg cttgttattg ttccatctat atcaatacat atattcaatt
    94501 tgttcatttt tacctccatg taacatttat tgatttgatt aatcaaatat tatagcacag
    94561 ctttaattat aaatcaaaac tctggatatg actataccta tataatacca aaaagcttgc
    94621 atatttaagc aagcttttcg taaattttac atttttaact aatatataag tttttctaag
    94681 gttggttcca ctccaaattg tgatttcagt tctttatatt cttttaatgc tttgtcatta
    94741 ttcgttttag tttttatcgc tcttatcatt aaattttttg gtgtatcaag tggagatatg
    94801 tattctacta cagaagtatc atatccattg ccctccaata acaatgttct taaaccatca
    94861 gttattaaat ctgcaaatct agctttaaat acaccatgtt ttaatattgg ttccatagct
    94921 tcatatctat attgccctaa tagctcctta tgacaacatg gtactactac tatagcttca
    94981 gattttgctc taattcctag acctattgcc atatctgtag ctgtatcaca agcatgtaga
    95041 cttattacaa ggtcaacatc cctattaggt gtataattag tcaaatcctc ttttataaat
    95101 gacatatttt tataacccaa gtttttagcc atattttttg atgcttctat aactacatct
    95161 gaataatcta ttcctataaa ataacagttt ttcttcaata cttcttttat ataaaaattt
    95221 aagacaaagc ttaagtaaga ttttccacaa gcacaatcca agatagttat acagtcttta
    95281 tcctttattt cttttaaaat actatctatc aattcaacaa aatggtctat ctgattgtat
    95341 tttcttattt tatcattttt tatcttacca tcttttgtaa gtactccaat ttcttttaaa
    95401 agtgcatttg cttgtcctac ttttacataa taatctctgt tttttatttg agatgccgta
    95461 aattcatcta ttttaggtac ttcttcctta ttatctaaat attttacatt taccttctta
    95521 ttgtctcctt caattacaac aatagttcct cgctcaacat atttaaatac taatccatca
    95581 taattttctg cctctttaga aatattctta agcaactcat taaacgtata taaatctgat
    95641 tttcctttaa aattaaattt atatttatta tcttcctcta ttgcaattcc tttaaactct
    95701 tttcttccag atttaaaaat cacctctaac tcaataaaaa aatccctatt atcaaggttt
    95761 ctttgagtaa tccccataaa aaacatattt agttttccta tactctgttt attcatcata
    95821 atctcccttt taacttatat ctttaaatct tattaattaa tattatttgt ttctgaatta
    95881 tttatttctt cttttaaatc gttcaatcta tttttaaaac tttctatctg cttatctgat
    95941 aaatcaagat attctgttat cttccctata tatttagggc ttttagtatt tattaatttc
    96001 aaagcacttt ccatagattt ttctctaagc tcatatgctt tctttacatc atctctagca
    96061 ttactcaatg tttctgtata cttctcctta gaaagttctg gaatctgcat attttcatat
    96121 tcttttacaa cttctttaca cttgtttctg gcatttgtaa catctttttt tatactagat
    96181 aatttagtta tattttttgc tatatcctta gtgtaaggta tacattctct cattggaact
    96241 aaagctgctc tttctatatt ataaatttct ttcttaaaaa ttcctatact ttccatatct
    96301 atttttttta tatcttcact atttttttct ttacttgtat atttattatt ttcttttgta
    96361 ttatcttctt gtttttctga tttattattc actgaaacat tactatcaga attattcttt
    96421 tcttttatat cattacttcc ttcttcatta ctttctttat tttgtatatt tctatcttgt
    96481 ttgttgttta aatttttatt atttgatatt tcttcattct ttttattatc ctgttttaaa
    96541 tcagtacttt ctttttcctt aaaatttgat acatactttt catcatatgt ctcatcagaa
    96601 atataattgt gataatacat agactctttt attttattaa gtccactcat ataaatatta
    96661 cttatcatta ttgttgtagc taataccaca taaatactac tgtagataca agacctctta
    96721 aaattcttgt aatttctgaa tatcactact aaaggaataa gatataaaaa tataaaaact
    96781 aatatccacc tcataagtcg tgtctccttt ctcaaaaccg aaatccctca aatatttatt
    96841 tttaatcatg tatcttatag tatttaccaa tttatgtttt ttaatcgtga acttttatta
    96901 aattaaattc tgtatagtca caagatgcta atgtatattc tactccattt cgaatcccct
    96961 tcaatcccat tttaaaagat tctttaccat gcaagtgacc ataaatcacc ttttcaacat
    97021 tatattcttc aaataacttt gtaaataaag attcttccaa tttatcattc gtaggaggat
    97081 aatgagtaat cacaattatt tttgagtggc cacttttacg agcagattct aatgatagtc
    97141 taagtctatg ctcttctctt ttataaactt tttcatcagt ctcatcaaat ttaacatcat
    97201 taggacatat ccagccccta cctccacaaa ttgcataatc tttatattca taaaaatttg
    97261 tctgaataaa acgcatgtct tcatatagct tatttaaact tgtaacggtt gtccaccagt
    97321 aatcatgatt tccttttata agtattttct gacctggaag tttgcttatt atatctaaat
    97381 cttttttagc ttccgataaa ttaattcccc aagatgtatc tcctagtact aagaccatat
    97441 cttcttcctt aacaacttct ttccaattat ctataatttt cttttcatga ccatcccaat
    97501 tacttccaaa gatattcatt ggcttattga ctgatgttga aaaatgtaaa tcacctatag
    97561 catacaaact cataatatca ttcctttctt aattacacta aataggctgt ctctttttag
    97621 aaattatttt ccattaagag gcagccccat taatatttag caaattttct acaagtagtt
    97681 ttactgaact actttatcat ctaccttagt atccttatat tgctctagta atatatctat
    97741 ttcttgtttt aattccaaaa tttcagttat atttttatct gtttcagttc tatcaagttt
    97801 tctttggtac tgcatagctt tatgtgtatc acccaagtca tataactctt gtattctatt
    97861 tagagtatct ctaatagcta tagacttcat ttggtacata gcctgagctt tcattatgtc
    97921 ctctcttatt tcactcattt cttggtctaa aagaaaggca gcatcagatg ctcttctaag
    97981 cctttcagca agagtctcag gtatgtaatg gtcatattta tattttaatg aatgttctat
    98041 tgtagcccag aaattcattg caagagttct tatttgtatt tcacatataa tttcctttga
    98101 acccgcaatg gagtttatag ggtattttat tataacatga tagcttctat aaccactatc
    98161 tttgtaattt gtaatataat ctttttctcc tattatagtc atatcatttc ttacttttat
    98221 caaatcaact atagcatata tatcctcaac aaactggcac attattctta taccagcaat
    98281 atcatcaatt tcagtttcta tatcttttgc atttatcctt tttaacttag atattatgga
    98341 agatattttt tttgttctac ctgtgacaaa ctctatggga gaatattcac cttttgctaa
    98401 atattctttt cttatatttt taaattttat tttcaattcc tctactgcat gttcataagg
    98461 tgctagtatc tcattccatt tttcgtattc catattgctc accctttatt tgttttttat
    98521 gaccttcttt attttatcat aatttatttt gtttttgtat agtaaagcaa ttctccattt
    98581 tccaatatat accctatttc ttctaaatca actaagtaac ttatgacaga tactaacgaa
    98641 gatttaaaaa aatgatactc tttataatta ttgcttaaat tattgttatt tataatgttt
    98701 tttaataaaa tttctaaaga tttcggttct acaagcaact ctcttatttg atataaatat
    98761 ttttttaaag cattcaaatg tttttctatt aatttataag aatcttcttt cgatataact
    98821 tgcttgccat gccctaaaac taagtactca aaatctatat tttttaattt ttctaatgaa
    98881 tttatttgtt cttgtatatc atatagaaac aagaaatcgt attttgatag aatttcatct
    98941 cctatcaata aatcgccaac aaaaatcaca ttatccttcg tcaaaacagc tatactacca
    99001 ggtgtatgac cctgaaattc aattatatca aacatttcat tgtttaattc aatttttcca
    99061 gcttctatag atttatctat ttttatatca tccaacattt tattttttaa gatattatcc
    99121 ataaatacat tgctctttcc cccaacaata tactttgaaa acaattctgg attttctata
    99181 tataatttat cgtattcaga tgacattata cacacatctt tataatattc tttaaattga
    99241 ttacaagctc catagtggtc atcatgacca tgagtattta taatatatct aacctgtata
    99301 ttattttcat ctaatacttt atttactctc ctaggtcttg aaccacataa ccctgggtct
    99361 atcataagtg ctgtgttatc ttcaaataca tatattcctg tattcgtgcc accttttata
    99421 aaaaaggtat ttccttttac ttttgtaaga ttcaccttct tcacctcatt ttgacaatat
    99481 ttatgataca atttattact tactaatata aaactataca agaacaatcc tttttattct
    99541 atctatagtt ctttttctta ttttgtattc tttagatatc cttattttca cattatatgc
    99601 taaatttcta taaagtaatg actctataaa atattcaact atacctctat ccctaaagtc
    99661 tatatctata tttccacttg aataaatatt tgagtctaat atcataagct catcaaaaaa
    99721 gcttaatctc ttagatttac ttaaataatc tttatttgga ataaatctat cacaataatc
    99781 tatcctgtaa tttactactt catcatttat ttcaaatcca tattgctttt tcattaactc
    99841 tctatagtta ttatttttct caataacatt atctaaattt ttattataat cctctttttt
    99901 ccaatgtcca aacatcctac aatttaatgg tctaacttca tatattaaac atctattatt
    99961 agtatcttta aatggacatg ggttctttct tgtatactcc tcaaaataat aatctaatat
   100021 tttacttata cagctttttt ttaaatcaac tctatcttca agataacaaa atatattcaa
   100081 aaactcaatt aaatttatac ctactgactc catacaacaa tttccacatc cagaacaatt
   100141 tcctactggc aaggacttat atacatcatt tagtttgtca aagagcttat ttttaatgga
   100201 ataatctata caatttaaaa tatctttatt ttttatacta gtcattatta ttactccttg
   100261 ttataattat taagttaata caaacaatta ttataacata ttttttaaat ttaatcgcat
   100321 atggaggtat tttatgaata gatatacaaa aataattaat atgatgggaa gttattacac
   100381 aaaagacttt gaaaaagaaa aaaagaatgt aataaaagtt agagaagtta aagaagatac
   100441 agttagaaaa tttttcttac aaggtgactg tgaagttctt gtagtatttg aagacactgg
   100501 gaaagaaata cttattgatg acttttctcc tgaagaagat atcaaaaaat atttaggagc
   100561 aaaatttata aataaaaaaa gatagttatc aaaaataatt ctaaaattaa aatttaataa
   100621 atgtacagtt ataattctat ataattatag ttaaaagtta tcttttattg cttttttaga
   100681 ctttaagata gctttttttc tattttttgt aaaataattc cataattcac attaataatt
   100741 cacaaaatga tataatataa caaatagata aattttaaat ttctaaatac ataattaata
   100801 ttttgcgagg tgattttatg caaatttatt ttagagttaa ggctgttggc aaacgcaaac
   100861 ctatgctaga acttacccct tttgatgtat ctgacaacat caattgccta aaagaagcta
   100921 tctctgaaat tgtatctaaa aatgttcttg aatataatga gaaaatccca gaaaaatcaa
   100981 taataaactt cttaactaat gaagaaattg aatctcaagc tgatattgga aaagttggat
   101041 ttggctctat ttacaatgag aataaacaat ctgtagaaaa ggcaatagaa gtagcgttac
   101101 aggcatttga agatggaatc tacaaagtgc ttataaatga agatgttatt gaaaaactcg
   101161 attcctctat aaatctgaaa agtggagata tatttacttt tataagactt accttgcttg
   101221 ctggaagaat gttttaaaat aaataatttg gaggtacata aatgttagaa cgtactagag
   101281 tagaaaaaaa tcctaaaata attgaaaatt ttaaaaataa ttttactaaa tcttcttcaa
   101341 aacagtacta cgacttagca aagtctcttt gggactgcat agaaaatagt tcatactatt
   101401 atagagaacc tgaagacaaa ttcttaaata tgataaagaa atactacaat tgccactact
   101461 acgaaattaa aaatatggac gagctccttt ctggaccttt aaaaaatgca ttagaattaa
   101521 tatttacttc tgaacaagta gaagaacttt gccaattaat taaaagaaag atggattata
   101581 catattcagg aggatattat cgtaaagggt atcgctcaaa taaacttgtg gattatttta
   101641 gaggtattat aaggtttatt tcaaactatg ttgatttaat ttattatgat ttttcagtta
   101701 tagattatct tactcttcca aataaggtct tgtactatga ctctataatg agtgataaaa
   101761 tagcactaga aatagacaaa ggaaatcaaa aagtaataag tgctttagaa gaagtaatat
   101821 ttggagaaaa tcaaactgct ctacttacaa gacaaatgat aattggtatc atgaagagtc
   101881 atagtgataa atgctatgaa atgctttcta aactcctttt ggcagccaaa caacaagaag
   101941 gacttagaca gcaaattgta gagagtttag atgagggtac aatttctgca tcaatataca
   102001 tgttaaaaac tattttggac aacaatttag agcgatttag ttctgttata agagccttgg
   102061 atacatggac aggacttggt ttttcagacc aaaaacctgg aataatacgt aaatgtttag
   102121 aactttcata taaatcattg actgatgaaa agttccgtat agaatcaatt aatagcaatg
   102181 ataatcttga aatttatttt gccttatggg ctactgcaac ttacaacata tatgactctt
   102241 tctctcttat tgaaaactta ctttcttgtc aggaaaaata taaaaaactt gtagctcttt
   102301 actttttatc gcatacagaa agtacatatt ttaaacattc tatagcatct aaaaacatta
   102361 agggtgatga tttagagata ctagcatggg taattacaaa tttctatgta gaaagttctg
   102421 ttggctacta ctatagttgg caaaacagag aaactaattt tgacttgtca aacactccta
   102481 ttgacaaaga ctttgatgct agaaaagaac aatttgaaag tttaaaacat actttagaaa
   102541 ttttaaattc aaagacaaaa tcattttcag gaagtgtatt tccatggact tggattgaaa
   102601 tttcttctca tgaaatactt aaatgtatga tgactttaac agcatacgat atgaatgctc
   102661 aatttataga tgtgcttatg gaaaattgtc atcttatgag ttcagattta agagcttcac
   102721 ttatcgtcaa ttttgtaaat gaaccaaaga cagatagaca acgtgaattt ttattggaat
   102781 gtttaagtga taagagtgtt tccaatagag aaacggtatt gagtctactt agaaagcttg
   102841 agctaacaga tgtagaatta gataagataa ccaatctatt gtctttaaag acaagctcta
   102901 ttagacaaac agtaataaaa attttacttg aacaagatga ttcaaacttg gaaaatattg
   102961 cttcttcact gataaaatct tcaaattctc aaaaatgcct tggaggtctt gaaattgtaa
   103021 acttattaaa agataatact gctagacaag aactatataa taagcttatt ttacttatag
   103081 aggatattga taaatctaaa aagaatacat ctcaagttca aatactaatt gataatttgt
   103141 taggtaaagc aaaaaatgat tactgcaaag aaaatggttt tggaatatat aaccctgaaa
   103201 acaaagttca aattccagaa caatttgatt ttaaagatga ttctaatagc tcatcaaagc
   103261 ttaataaaat tatctcaaat ataagtttat ctactcgtga ggattctgtt tctgtagcaa
   103321 caaaaaaaga agcaaaaaaa attctcgata cggatataaa taaaataata aaagtttatg
   103381 aaaaatttga tgagcttatt actgaaaatg cagattatga atatgaagtt gaaagatggt
   103441 caggtaatgt agacaaagta cttttaggtt attctactta taacttgact cctattaaat
   103501 ataaagtttc taatgatact cttgataatt atccattagc agagctttgg agagaaacta
   103561 gtaaaaaact tgacttagat tacaaattaa tacttgatat cttattttat agtataagta
   103621 tatgtggata taatgaaaca gaaaaaagtt ggttttcatc tatatattca aatgtccttg
   103681 actctaaaaa acaaaataaa atatatacaa aacttgaaaa acttaaattt aatggactta
   103741 caagaaaact tttaagagtt ttactaaatg agtttgacca taaagaaata tttaactatt
   103801 gtttagaaat atactataaa cttagaaact tattgactat agaacaatgt aaaaaacaaa
   103861 gagttgaatt tactaaaaac tattacagac aaaatgaata ctgccctgct ttaaatgccc
   103921 ctattttaaa ctattggctt gataaagcac attcgtttat ttatgatgat atttctttta
   103981 ctaagttttt ctacactacg ttttcaaatt atcagttgct agaatataag tttcctttct
   104041 atactagcat aaatgtgttt gctcgtgcac atgaattagg attaatgact gaagagcaag
   104101 ttaatagaga aatgataagt ggatacaacg catcaaatat aataagaaca ttgacaaatc
   104161 ctagatgggc tggcgacaca ttagaaaagt acccttggct taaagataat ttaaaaactg
   104221 ttacaaaccg aattatagaa attgaatcac gtagaggtga tatgccaaca gaagtatctc
   104281 atctagctaa taatatacaa tactttgaag gtataaatta ttttgtaaat attttggtcg
   104341 ctcttggtaa agaaactttc cagagaggat attcatatgg tagcaattat tcaaaaaaag
   104401 atgttttaag ttctctactt aaaaattgct atcctactaa agaagatgat tcaaaaaaat
   104461 taaaaagttt acttaaaaat accgacatta ctgagttaag attgatagaa tctgctatgt
   104521 atgcccctca atgggtaaac ataattgaaa aatatttaaa ctggaagggt ctgaaaagta
   104581 caatttggta cttccatgca catataaatg aaggcttctc tgcacaaaaa gaatcagagg
   104641 ttgctctatt ctcccctatt tcaccacgta gtttcattga tggtgcattt gatgtagatt
   104701 ggttcttaga ttcatataaa actattgggg aagaaagatt caatatactt tacaagtcag
   104761 ctaaatatat aactagtggt ggtaactctc atagacgtgc acaactctat gctgatgcta
   104821 cacttggtaa gcttgataaa gacatgttga tgaaagaaat tgaaacaaat agaaatcaag
   104881 ataaattgag aagtttctct ttacttccta tgaaaaaagg agacctaaaa gaagcaactt
   104941 tccgttatga atttattcaa aagtttgcta aagaaagcaa gcaatttggt gcacaacgtc
   105001 gtgaaagtga atcaaaagct tgtactatag cgctagaaaa tctagctaga agtgctggat
   105061 ttggagatgt aaatcgtatg atgtgggctc ttgagactga aaaactaaat gaagttgctc
   105121 atctatttaa accaaaagat attgatggta cttcaatttg gatagatgtt gatgaaaacg
   105181 gaaaagcatc tactaaagtt caaaaaggca acaagtcttt aaagagtata ccaaaagcta
   105241 ttgctaaaca tccatatgta cttgaactta aatctgtcca aaaagattta aagagtcagt
   105301 attctcgtgc aaaacagagt ttagaacaag ctatgaaaaa tgaaatagta tttacagtta
   105361 aagaaattgc caatatctat aaaaatccag ttatctgccc tttgattaaa aatctagtat
   105421 gggtatgtga tgataatatt ggatatgttt ataatgataa gtctaagttc tttatttgca
   105481 atatagaagg tgaaacttat aagttgactg caaaaaataa attaaaactt gcacatccag
   105541 ttcatttgtt tgaatctggt aagtggagtg agttccaaca tgatttattt agtaagcaaa
   105601 ttgttcaacc atttaagcaa gtattccgtg agtattatag aataaacagt gatgaattat
   105661 ctgaaaaaac tatatctcgc agatatgctg gtcaccaaat tcagccaaag aaaactgtag
   105721 cacttcttag aaatcagctt tggactgtcg attatgaaga gggattacag aaagtatttt
   105781 ataaagaaaa tatagtggca aagatgtttg cacttgcaga ttggttttca ccagcagata
   105841 tagagcctcc tactattgaa acagtagaat tttttgatag aaaaacttat aaaagtttag
   105901 aattagcttc tatacctcca attctattct cagaagttat gcgtgatata gaccttgttg
   105961 taagtgtcgc tcatgctggt ggtgttgacc ctgaaactag ccattctact gtagagatgc
   106021 gtatagcaat tgctaaagaa cttttattat tattaaaaat taacaatgtc aattttgaag
   106081 gctctcatgc tcttatagca ggtaatttag gtgagtattc tgtgcatatg ggttctggta
   106141 ttgtacataa aaaagggatg ggtgctttga atatacttcc tatacattct caaagtagag
   106201 gtaagatatt ccttccattc gctgatgaag accctaaaac tgctgagatt atgtctaaga
   106261 tactattact tgctgaagat agtaagatta aagaccctag tatcttaagt aatttataag
   106321 tataaaaact atccctaaaa tatattggac ttcttagttt ataataaaaa tattgctaga
   106381 aaagcagatg taattatatc tataatagat agagagctta aattaacact ctaaaactat
   106441 ttatagaaaa gaggatttaa atgttattga ttttaggtaa tttaaattta aacttggatt
   106501 ttgactacag aataataaga gaagaaaatg aagatgtaga tatatttata gatattaatt
   106561 atcgtagctt agatatagat actgatggtt ctaacttatt taattctaga atacaatttc
   106621 catttgtaag agcattgatt ctaaggctaa ataagaacaa tcaatgtatg acaattcatt
   106681 tgttaagaga tatagattta ttctctgctt ttgccaactt tgaagtggat tatactgact
   106741 ctataataaa tataaaaaat caaaatgaga aagtaatttt aaataaatct atcaaaaaat
   106801 agtaaggggg ccttaatagg ccccaatttt tttcttttct aaacttatta tatcatgata
   106861 aataaattag tcaatagaat tttctgaata tttttataat tttttcataa agttttttat
   106921 atattatgct ttaaaattat atgtaataaa aaaattttcc gactaatttt aaagttaatt
   106981 gattaaatac acatattcga aattaccatt aaattactga ctttttatca tttccactta
   107041 gaatttaagt tataatctat tatttatagt tacttctaca tgtctctaat aaaactctat
   107101 ttatattcaa atctaataat ttatatacaa acccaataga acctatgttg cacaatagat
   107161 attatttacc ataataaact tttagatata tctcttttaa ttcactcatc aatgggtatc
   107221 taggattagc acctgtacat tggtcatcaa aagcttgttc aaccatagca tccaatcttt
   107281 ctaagaattt agattcttct actccagcct cttttatagt cttaggaaga cctacttttg
   107341 cctttagttc atctattgct tttataagat tatctacttt ttcttggtct gtacttcctt
   107401 taatacctgc aaaagaagca aattcagcat atctttgtat gcaatcagga tatctgtatt
   107461 gtgagaatgc acccatctta tttggagctt ctgcacaatt gaacttgatt acttcattta
   107521 ttaataatgc atttgcaaca ccgtgttgaa catggtggaa tgcacctaat ttatgtgcta
   107581 aagagtgaca tattcctaag aaggcatttg caaaagacat tcctgccata gtagatgcca
   107641 ttgccatttt ttctcttgct tctttatcat tctttccatt tttatatgca cgaggtaaat
   107701 attcaaatat tattttacct gcttgtagtg ctagaccgtc agctggttca gttcttaaca
   107761 tagatacata tgcttctaat gcatgtgtta aagcatcaac acctgatgct gctgttaatc
   107821 ttggtggcat ctccatcatc atatcagcat caattatagc catgtttggc attaattcat
   107881 aatctgctaa tgggtacttt acacctgaat cttggtcagt tataactgca aatggagtta
   107941 cttctgaacc agttcctgct gaagttggga tagcagcaaa atacgctttt tcacccatct
   108001 taggaaatac atatactctt tttcttatat ccataaatct catagctaag tcttggaaat
   108061 ctacttctgg atgctcatac attacccaca ttatcttacc agcatccatt gcacttcctc
   108121 cacctacagc tattattaaa tctggttgga aatcagccat agctttagct ccttctcttg
   108181 cacaagctaa tgttgggtct ggagctacat caaagaatgt agtatgctta attcccatct
   108241 catctaataa atcagttaat ttcttagtat atccattatt atataggaaa gaatctgtta
   108301 ctataaatgc tttcttttta tccataacat ccttaaattc tcttgctgct acacctaaac
   108361 atcctttttt gaaataaacc ttttctggtg ctctgaacca aagcatattc tctctccttt
   108421 cagctactgt cttgatatta agcaaatgtt ttactccaac gttttcagat actgagtttc
   108481 caccccaaga accacaacca agagtaagag acggtgccaa tttaaagtta tataaatcac
   108541 ctataccacc ttgtgatgat ggagtattaa ctaatactct acaagtcttc atagcattta
   108601 caaacttttc tactctctct ggatgattta tagagtctgc atataatgaa gatgtatgac
   108661 catagcctcc atctgcaact aatttttctg ctttagcaac tgcatcttca aaacttttag
   108721 acttgtacat tgcaagtaca ggagaaagtt tttcatgtgc aaaaggttca tttaattcaa
   108781 cagattctac ttcaccaatt attattctag ctgtttttgg aacttctaca tccgccattt
   108841 tggctattac atgtgctggt tgtccaacta ttctggcatt caatgaacca tcaattatta
   108901 ctacttttcc tactttttca gtttcttctt tatttaggaa atgtgctcca cgatatttaa
   108961 attctttttt aacttcttca tatatttttt ctggtactat tacagcttgc tcggaagcac
   109021 atatcatacc attatcgaat gattttgata ctaagattga acttacagcc atttttatat
   109081 ctgcactctc atctattatt gcaggtacat ttccaggccc aactccaaca gctggtttac
   109141 ctgaagagta tgcagattta accattccag gtccaccagt agctaatata aggtctgcct
   109201 ctgccatgac aacattagtt aattcaatcg aaggaacatc tacccaacct ataagtcctt
   109261 ttggtgctcc tgccttaact gctgcatcat gtacaactct agctgcttct atagtacagt
   109321 ttttagctct tggatgagga gagaaaatta taccatttct agtttttagt gctattaggg
   109381 atttgaatat tgcagttgat gtaggattag ttgttggtat aactgctgat aaaacaccta
   109441 ctggctcagc aattcttgta aaaccaaatg cttcatcttt ttctatgaca ccacaagttt
   109501 tagtatcttt ataagcatta tagatatatt ctgaggcaaa atggtttttt ataaccttat
   109561 cttcaacaat acccatacca gtctcttcca ctgccatttt tgctagaggt attctttgtt
   109621 gattagctgc agttgaagca gctaagaaaa tcttatctac ctgttcttgc gtaaatgttg
   109681 caaattcttt ttgtgccaat ctaatttctt ctaatctcat tcttaatgtt tcaacactgt
   109741 tgacaatttc aggactacat acttcaacat ttgatttttc tactaccttt tcttttttct
   109801 ccatactaaa aacctcccta aaataattat gcatctctaa tttttataaa tcttaaatgc
   109861 atcatctata tttttaactt atacttaaaa taattttata gatttcatct ctatacctta
   109921 gattttattt attttactct cttaggtcaa gaagtttttt tctgaatatt ttgtcaattt
   109981 attttttaac aaatatatta ttttttttac ttttactaaa attttttatc taaatgagat
   110041 atatttcatt tgaataattt actttgacta aataaaatac taaaatgata atttatatct
   110101 ttcatttttt ttacttatta aattttatat gttatttgca tgttatttgt ataagtagta
   110161 aataaaattt ttgtcgtatt tttataaaat aacacttatt tttgacttgt atgcaatttt
   110221 tctttttata acaactgtat agttttaaaa aatatataaa ctaaaattat tctaatctct
   110281 ataagttatt tttaagtcaa tatgtaataa ttatgctttt catataga
//
LOCUS       DAEORM030000006       104245 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.006, whole genome shotgun sequence.
ACCESSION   DAEORM030000006 DAEORM030000000
VERSION     DAEORM030000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 104245)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 104245)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 104245)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..104245
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.006"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            110..301
                     /locus_tag="KRH23_000607"
     CDS             110..301
                     /locus_tag="KRH23_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF378 domain-containing protein"
                     /protein_id="HHS5223903.1"
                     /translation="MKKVALILAIIGALNWGAIGILGTDLIGSIFGGTYEMVSRIIYF
                     IVGLAGLYLIPSLMSDDRE"
     gene            456..1865
                     /locus_tag="KRH23_000608"
     CDS             456..1865
                     /locus_tag="KRH23_000608"
                     /EC_number="4.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HHS5223904.1"
                     /translation="MFIINELNKIVNEEVISFHMPGHKKGQVYKKLGYKDILKNLYKM
                     DTTEILGTDNLHFPEGIIKNSQKKASRVFKSDYTCYLVNGSSCGIQSAIMSVCSPKSK
                     IITNRDCHQSVINGCILGDIDIEYVPCEISEETNILKGISISNVIDIIDKNLDAKAVL
                     LTYPTYYGMTYDLEYICNYAHSKKMVVIVDEAHGAHLGLSERLPKTALEQGADIVVQS
                     THKTLPAFTQSSMIHIQGDRVDIDKILNMLRITESSSPSYLLLSSLELAVDIYENKGK
                     ELMEELLNNIITFKNKVDSNINIYDTNDKTKIFISSKNMGLTGYELENILRNKYNIQV
                     ELSNYYGVLLICTIGNTAEDFSSLETALNNVVKEDFKFEKLENKKYPVVIPKKILTPR
                     EAFYKTKKSVKIYDSIGKVCGECIVPYPPGISVISPGEVISKEIIDYLMFCHSKGMIV
                     SGLKDVDLNFIQVIDLEDI"
     gene            1996..2685
                     /locus_tag="KRH23_000609"
     CDS             1996..2685
                     /locus_tag="KRH23_000609"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004798 - dTMP kinase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006233 - dTDP biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HHS5223905.1"
                     /translation="MKGKLIIIESGSDASGKATQTEILYERLKKEGYMIKKVEYPNYE
                     SPSSALVKMYLKGDFGKNASDVDPYIASTFFTADRYASFKTDWEEFYNEGGIIIADRY
                     TTSNMVHQASKMDICDREEYLNWLADYEFNLFKIPQPDCVIFLDVPIEFSKKLMENRK
                     NKITGEEKKDIHESDIEYLEKSYNNALYIADKYDWKKINCVLDNKLRSIESIHNEIYK
                     IVLDSIKPMER"
     gene            2688..3623
                     /locus_tag="KRH23_000610"
     CDS             2688..3623
                     /locus_tag="KRH23_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HHS5223906.1"
                     /translation="MYFENIIGQDFAKKYLTNSIKKNKLNNAYMFEGMDGIGKKKFAD
                     ELSKLLLDYENLENSPDYVLIKPDGNSIKIAQIRNLQSDIVIRPHKDYKIYIINNAEK
                     MTVEAQNALLKTLEEPPNYAIIILVTNNKESLLETIKSRCDIIKFSPIPIEDLKRYLI
                     NTGIEEERAQLLAIFSRGSIENALNLSQSSEFSMMREDIQQYIQIMLDKNIVEILNIP
                     NNMEKYRGKIIALLDMMINYFRDIILLKENVNKNMLINVDKLVFIQNMSGKISYSQLS
                     KIIDIIEDAKSKIKSNCNFNISIQVMSLNIYEVIK"
     gene            3620..4513
                     /locus_tag="KRH23_000611"
     CDS             3620..4513
                     /locus_tag="KRH23_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PSP1 domain-containing protein"
                     /protein_id="HHS5223907.1"
                     /translation="MIKIVGIRFKSAGKIYYFDPVDFNIEQDMDVVVETARGLEYGKV
                     VVGPKDMDESELVSPLKPIIRIATEEDKKVYLENKEKAKETFELCQQKIKEHELTMFL
                     IDCEYTFDRNKLIFYFTAEGRIDFRELVKDLAAIFKTRIELRQIGVRDEAKSIGGLGP
                     CGRKLCCSSWLGDFQPVSIKMAKDQSLSLNPTKISGICGRLFCCLKYEHDVYSEAIEK
                     MPVVGALVQSDDGKGKVVEVNPLLEQIKVEFQDKTVKIYTREDIKILREPKKCDGCGG
                     KCKDNDGLDEATLRELKKLED"
     gene            4591..5337
                     /locus_tag="KRH23_000612"
     CDS             4591..5337
                     /locus_tag="KRH23_000612"
                     /EC_number="2.1.1.223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008170 - N-methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:0016430 - tRNA
                     (adenine-N6)-methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HHS5223908.1"
                     /translation="MQLKDSERIDDLQLKGLKIIQDTNGFCFGIDAVLLANFTKIKKD
                     AKVVDLGTGTGIIPILIAGKSEAKKIIGVEIQEDVYEMATRSIKLNGLEERVEIINED
                     IKYIDKVLDINGYHVVTSNPPYMHIDGIKNPNDKKAISRHEVRCNLEDVIRAASRLVM
                     PRGKFFMIHRPTRLVDIITLGRKYKLEPKVIQFVHPRPQKAPNLVLVQFVKDGRPELK
                     ILDPLYVYGEDGNYTKELKAIYNNKDIGEL"
     gene            5338..6171
                     /gene="rsmI"
                     /locus_tag="KRH23_000613"
     CDS             5338..6171
                     /gene="rsmI"
                     /locus_tag="KRH23_000613"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0000451 - rRNA 2'-O-methylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HHS5223909.1"
                     /translation="MSGKLYICPTPIGNLEDITYRTLRILKEVDLIAAEDTRHSIKLL
                     NHFEISKPLTSYHEHNKDSKGDYLINKLIDGENIALISDAGMPGISDPGEEIIKQAIQ
                     NNIEIEVLPGATAFVTALVGSGMDTHRFVFEGFLDRDKKVRKAQLEELKEESRTIIFY
                     ESPHRLKDTLKDMLKILGNRNISINRELTKKYQEIIRENIETTIKIFEEKEVRGEFVL
                     IVEGFHGEKSKKENYDGLTDREYVLKLIESGMNKKDAIKIVCKDRKLKKDVVYKQVLD
                     L"
     gene            6194..6898
                     /locus_tag="KRH23_000614"
     CDS             6194..6898
                     /locus_tag="KRH23_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDIG domain-containing metalloprotein"
                     /protein_id="HHS5223910.1"
                     /translation="MEIGKIIIESLKREDTHKIFIELDNKHELEKIIPKISCMKSVGE
                     CKYHVVNCFEHSINALKELEIVLNDKDFFPIHLRKHVSNYLKTYIEEGINKLHVLKLG
                     TFLHDIGKPDSMTLDETGRVHFTNHEKIGAQIIDNMGIKLELSTETYRLISKYVRYHM
                     ILLSLYKKNDLSRKELINVFNLVDEDTIGVIMLGYADIVSTVKLLGKSGEVSVLKTYM
                     EYILTNYLYKSNYTHV"
     gene            complement(7086..7514)
                     /locus_tag="KRH23_000615"
     CDS             complement(7086..7514)
                     /locus_tag="KRH23_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007287587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="HHS5223911.1"
                     /translation="MDVTDYRIIEILQDDGRISMKDLGKIVGLTSPAVSERVKRLEES
                     GVIEGYKAIVNPDSLGRVIKAFIHISLPSNGYTEFIESAAKDPRIVECHHITGDDCLL
                     LKVIVKDMYELENVIDTIKKIGSTKTSVILSTPIQAKSIL"
     gene            complement(7551..8981)
                     /locus_tag="KRH23_000616"
     CDS             complement(7551..8981)
                     /locus_tag="KRH23_000616"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004516 - nicotinate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HHS5223912.1"
                     /translation="MRNLTLLTDLYQLTMLNGYFEKNIHEDIVVFDMFFRKNACDGGY
                     TIVCGIDQVVEYIDNLHFSDEDLEYLKNLNLFSDKFLKFLKEFKFTGDIYAVEEGTIM
                     FPNEPLITVKAPLYQAQLIETALLTIVNFQSLIATKASRVCFAAQGDPVFEFGLRRAQ
                     GPDAGIYGARAAVVGGCAGTANVLAGKMFDIPIIGTQAHSWVQKFDNELEAFQAYADV
                     YPDKCLLLVDTYDVLNSGVPNAIKVFKNISEKGYKPMGIRLDSGDLAYLSKEAKKQLD
                     NAGFSDISITASNDLDEYTITSLKAEGATINSWGVGTKLITSFDSPSLGGVYKLAASC
                     EKGVLEPKIKISENPEKINNPGYKKVIRIYNEDNKAEADLIMLHDEVIDESKPLEIFH
                     PTYTWKTKVFTNYKVKELLKPLYIKGRCKYNKKAVLEIKNHVQYELSTIWEQYKRLSK
                     PHIYKVDLSRNLWYLKTQMIDSKKVL"
     gene            9113..9697
                     /locus_tag="KRH23_000617"
     CDS             9113..9697
                     /locus_tag="KRH23_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore maturation protein A"
                     /protein_id="HHS5223913.1"
                     /translation="MIIIGKIWFYMVSIGIIGSLISKNMGELNKVILSETSKGIEFAI
                     SLAGIMALWMGIMNIAKESGLIEKIGQKLNPIMRRLFPSIPKGHKAMSYIVMNIALNM
                     LGAGNGATAFGLKAMSELQTLNNKKDTATNDMIMFMVINISSIQIIPFTIIKLRMDMG
                     AQNPSEIIFTTLFATIISTAVAIITCKFFQRRYR"
     gene            9713..10234
                     /locus_tag="KRH23_000618"
     CDS             9713..10234
                     /locus_tag="KRH23_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore maturation protein B"
                     /protein_id="HHS5223914.1"
                     /translation="MEIFSNLLIPIIILYIVIYGKYKKIDVYDSFVKGAIDGLKAAWD
                     ILPYIIGIFLAIGIFKTGKGLDMLEWLFTPIANMMSIPKELIGLISVKPLSGSGALGM
                     YSELANRVGIGSLVEKMGATIVGSSETIFYTMAIYYGSLKIKNTRHTLSCAMISHVAG
                     VIAAVFICYVIFV"
     misc_binding    10300..10546
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            10630..12567
                     /gene="metG"
                     /locus_tag="KRH23_000619"
     CDS             10630..12567
                     /gene="metG"
                     /locus_tag="KRH23_000619"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0004825 - methionine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006431 - methionyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HHS5223915.1"
                     /translation="MSKPSFYVTTPIYYPSGGLHIGHTYSTVAADTIARFKRFCGYDV
                     KFLTGTDEHGEKIQKKAIEQGMSEIEYLDGMIKDIKALWNTMDISYDDFIRTTEKRHT
                     DIIQKIFTKLYEQGDIYKGEYEGRYCTPCESFWTESQLLEGNKCPDCGRETYLVKEES
                     YFFRLSKYEDRLKELFKDDSFCFPAARKNEMVANFLDKGLEDLSVTRTTFDWGIKVPF
                     DEKHVIYVWVDALCNYITALGYMTDNDEEFKKYWPANVQIVGKEIVRFHTIIWPALLM
                     ALGLEVPKQVFGHGWILFADDKMSKSKGNVVYPEPIIERYGIDTLKYFLLREFAFGQD
                     GSYTHRNFVTRINYDLANDLGNLISRTVAMVEKYNNGIIPTAKVSTDFDADLKEQAVS
                     TRENFEAEMDKMQFHEALESVWKLVRRTNKYIDETMPWALAKDETKKGELDTVLYNLC
                     ESIRIIATLINPIMNETANKIYEHIGIKGQDDITTWESTKTFGLIGENVKVFKGEPLF
                     PRLDVEKEIEELTKMFSGKPPVEEKPLEHKEEITIDDLDKIELRVGKIISCEKHPKAN
                     KLLVSQVKIGPETRQIVSGIAEYYKPEDLVGKEVTVVCNLKPVKLRGVESQGMILAAG
                     DDGDPYVLPFTQGAKDGCEVR"
     gene            12597..13367
                     /locus_tag="KRH23_000620"
     CDS             12597..13367
                     /locus_tag="KRH23_000620"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004536 - DNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HHS5223916.1"
                     /translation="MLFDSHAHLNDESFDEDRDELIGSLKDKGVDLVVNPGADIETSI
                     TAIELAKKYDFIYSAVGVHPHDVSKLDDTAIETLRKLATENEKVVAIGEIGLDYYYDY
                     SPREEQKEWFKKQIELANELKLPIIIHDRDAHGDTFEIIKNTKNPEIGCVLHCYSGNV
                     ELAREYVKMGCYISIPGTVTFKNNKKTREVVREIPLERLFIETDSPYMSPEPHRGKRN
                     NPSQVSFVADKIAQEKGICYEEVCRVTKENAKKFFNIK"
     gene            13704..14135
                     /gene="phnG"
                     /locus_tag="KRH23_000621"
     CDS             13704..14135
                     /gene="phnG"
                     /locus_tag="KRH23_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015716 - organic phosphonate transport
                     [Evidence IEA];
                     GO_process: GO:0019634 - organic phosphonate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate C-P lyase system protein PhnG"
                     /protein_id="HHS5223917.1"
                     /translation="MYTVDSTKILINMNLEKLEKIYSMIKDTSSISIIKEPNLATVMV
                     RANESVKNTTFNLGEILVTECSVKVDESLGYGIVSENNNKKAIYLAVIDAVLHSNNSK
                     FDELKNYINKSVYEENLRYEQEIIDEFSLINKTKVQFNAMD"
     gene            14150..14725
                     /gene="phnH"
                     /locus_tag="KRH23_000622"
     CDS             14150..14725
                     /gene="phnH"
                     /locus_tag="KRH23_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0019634 - organic phosphonate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate C-P lyase system protein PhnH"
                     /protein_id="HHS5223918.1"
                     /translation="MVNYTQEIYRKMLDSASFPGKLNNIDNINIENNTKLLNGAIGIA
                     ITLLDQEVTFYIENYTQKDIKNIRALTMSNQIDYRKSDYIFLDINSEVDILQIKIGSF
                     EYPDESATIVHQVNDLSTYSQTKYIKLDLSGPGIKSKNSIYINGIREEFIERLSSINK
                     DYPIGIDLILVDKKGEIAFIPRSSKLSWEVL"
     gene            14728..15813
                     /locus_tag="KRH23_000623"
     CDS             14728..15813
                     /locus_tag="KRH23_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-phosphorus lyase complex subunit PhnI"
                     /protein_id="HHS5223919.1"
                     /translation="MAYVAVKGGEEAILQAKNILEFYRVKGDSLPIDVKQIEEQMSYA
                     VDKVMSEGSLYNKELSALAIKQAQGDILEASFYVRALRSTMPRITYSEPINTEEMRIK
                     RRISATFKDIPGGQYLGATRDYENRILNVELLEEDEKKNRHFRDSFINELETVDEIPE
                     FTKISNIFRKENLLQEEVCENKLEEVIDDITRNSLRFPVSRSAKLQALTRGESGVVSG
                     FAYAIVRGFGDEHPYISELRTGNVFIKVKHPIYEDEEIVIGDMLVTECEIVSKASQNK
                     TENSKTNSEDKNKMSLGYGLCMGNNENKAISMAILDKSLEPNSEKLAQDEEFVLLHID
                     GIDSLGFISHFKLPHYVDFKADVERIK"
     gene            15833..16702
                     /locus_tag="KRH23_000624"
     CDS             15833..16702
                     /locus_tag="KRH23_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-D-ribose 1-methylphosphonate 5-phosphate
                     C-P-lyase PhnJ"
                     /protein_id="HHS5223920.1"
                     /translation="MIYNYGFLDENTKKEIRRKILKAISIPGYQVPFGSRELPIAKGW
                     GTGGLQLTLSLIGKNDVVKVIDQGNDDSTNACNIRSFIASVSNVETTKDTLEATLIQT
                     RHRIPEEKLKSNQILIFQVPIPETLRIVEPSEVETRRMHSEEDYSRMWVYLYEDIVRF
                     NDISIAVEYPCKVNDRYLMNPSPIPRFDIKKLNMSDNLFLFGAGREKRIYAIPPYTKV
                     EPLEFEDYKFEEEKFEGKYCSLCNSTNTFLDEVYDSDTNEKYYSCSDTSYCEKVRLKN
                     NSIDVTIGGTWNE"
     gene            16695..17561
                     /locus_tag="KRH23_000625"
     CDS             16695..17561
                     /locus_tag="KRH23_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HHS5223921.1"
                     /translation="MSKINDSKRLENIDKQVLIGRNINLIYGDGCKKCFESTGYESNN
                     ICKYCGSIVACNNVNLELYEGEVLGIVGESGSGKSTLLKILFFQEHANSGEVYISHYN
                     KDTNILELSDQKKRYIKNHFMGIVYQNPHLGLNLDFSSGGNIAEKLLMANLYNVEKIR
                     DRGKELLIKTNIPVERIDHKPKYFSGGMQQRVQIAKALSNNPPILLLDEVTTGLDVSV
                     QAEVLDLIREIQRELKISMIVVSHDFDVIKMLADRTIVMKNGSVIESGLTDQIMEDPQ
                     HPYTQQLINSLL"
     gene            17602..18315
                     /locus_tag="KRH23_000626"
     CDS             17602..18315
                     /locus_tag="KRH23_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate C-P lyase system protein PhnL"
                     /protein_id="HHS5223922.1"
                     /translation="MKETILEVNNFSKDFELHALNKTITACSNISFEVSKGEFLGIIG
                     KSGAGKSTILKSIYKTYIPTTGEIIFNSEIYGNVDLAKIGDREMINLRKKEIGYVSQF
                     LKTLPRITAIELVVHSLIESGFEKDCSYDMAKDILNQFEIKENLWDAYPNNFSGGEKL
                     RLNLAQAMVKKPRLLLLDEPTASLDNQSKIYVKEKMLELKSQGTTMIGIFHDIEFMET
                     VIDKTFTMAKGTISESGVA"
     gene            18316..19485
                     /locus_tag="KRH23_000627"
     CDS             18316..19485
                     /locus_tag="KRH23_000627"
                     /EC_number="3.6.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA];
                     GO_process: GO:0019700 - organic phosphonate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-D-ribose 1-methylphosphonate
                     5-triphosphate diphosphatase"
                     /protein_id="HHS5223923.1"
                     /translation="MIKLIHNANIVLEDMILENGHLIIEGDTIKKVSNDKIDYAFDFN
                     EIDEIIDAKNLYVIPGIIDIHSDAIEKEIEPRPSTLLPFNMAFYELDKKLPANGITTV
                     YHSISLGDGVGVRSIDNSLKMIKNIDSYKNIDSKSINHKVHLRYEVLYYEGLEKVLEL
                     LDENKIDYLSIMDHSPGQGQYTNPTFYKEYATKVWGVTENYVDTWLDDLVNLHDNLDW
                     NKIANIIGIAKTKNINVASHDDDTLEKMDFIKNIGINVSEFPITLEVAKHSKKLGVLT
                     CLGAPNIVRGKSHNNNLKAMDAILEDCCDIVCSDYLPSAMIKSMCIVAERINNLNKAV
                     SLFTSNPAKAVGIYDERGSIKENKKADLVLVDIDSEYPKVLNTIVNGKTVYKREV"
     gene            19489..20325
                     /locus_tag="KRH23_000628"
     CDS             19489..20325
                     /locus_tag="KRH23_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HHS5223924.1"
                     /translation="MLTELHCHTSISDNNFTTEEIIKKAAEKNINILAITNHDTLSGL
                     DEALVLGEHYGITIIPGIEISAYDYKNRKRVHILGYNIDLNSQEIKNLCNPMVCDRHK
                     ASVKMVNKIIDLGYKISLEDVKKYSSKTGIFKQHIMKALIDKGYTDNIYSNLYKELFH
                     RGNGKVYVSLKYVDYRDAIKAIKNSGGICVLAHPGQMDNFSAIEEMVKVGLDGIEVYH
                     PSHNKELEKESLSYAKKYNLVVTGGSDYHGFYSQHNYELGSKSLNKEDLFKFRLALGG
                     VL"
     gene            20326..21321
                     /locus_tag="KRH23_000629"
     CDS             20326..21321
                     /locus_tag="KRH23_000629"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHS5223925.1"
                     /translation="MSFLQVKNVGKSYGQVKVLKDISIDIEKGEFICLLGPSGCGKST
                     LLRIIAGLEDKHGGKIIINDKDMTNSPPESRNFGIVFQSYALFPNMNVYKNIAFGLEN
                     KSISKSNIDKKVKEVLDVVELSGYEKKYPSQLSGGQQQRVALARAIALEPDFLLLDEP
                     LSALDAKVRLKLREQIRSLHRKLGITTIMVTHDQEEALCLADKMVVMNRGEIIQVGTP
                     KEVYKNPETPFVADFIGTINFIDDGINKIAIRPEDIKVESNRDSKDKDIKVGEILDIE
                     FRGFNYRITVEYRSKQMKLDVVSKVAEQMKLCIGSKINFKIPKEGIVQYKSEGCA"
     gene            21339..23027
                     /locus_tag="KRH23_000630"
     CDS             21339..23027
                     /locus_tag="KRH23_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0033225 - ATPase-coupled
                     2-aminoethylphosphonate transporter activity [Evidence
                     IEA];
                     GO_process: GO:0033223 - 2-aminoethylphosphonate transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     permease subunit"
                     /protein_id="HHS5223926.1"
                     /translation="MITSKNKRRISDSTIQKYFLIFSVIVLIVFILFPLVSLLKNAFM
                     DTSGNFIGISNFSKYVENPSLIASFKNSIFVSTVSSLISLCLAFIYSYAITRTNIKFK
                     DFFKTMGMFPLFAPTMLYGISLIYLFGNKGIFTTMGLEVPLYGPLGIIISQILFTFPQ
                     AFLILSVALSMADYRLYEAADSLGASEFKKFCKITIPGIKYSLLSSFFVSFILAFTDF
                     GAAKVVGGNYNVLATDIYKQVVGQFNIPMGATVSMVMLIPVLIAFTLDKMASKKQGMT
                     ITAKSMPYKIKENKFRDRVFLIVCSFITLLIFILIFVSVIGSVIKLWPYNLSFTMEHY
                     TFKGILGSGIKTYLSSLKISTLTAIFGTIFVFFSAYMIEKVDKFPKLRQTAYLLSMIP
                     MALPGLVLGISYITFFNSASNPLNFLYGSTAILVIVNVVHFYSVCFITSNSSLKMLDK
                     EYELVAKSINIPFYKVFFNITVPMSITSILEIVVYYFVNSMVTVSALIFLYTPQTQTA
                     SISILKLDEIGYIGPSAAMAVLVLLTNIIVRLLYEFVTKKLKNNTQKWQQKDVA"
     gene            23039..24106
                     /locus_tag="KRH23_000631"
     CDS             23039..24106
                     /locus_tag="KRH23_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009897 - external side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0030288 - outer membrane-bounded
                     periplasmic space [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0033225 - ATPase-coupled
                     2-aminoethylphosphonate transporter activity [Evidence
                     IEA];
                     GO_function: GO:0033226 - 2-aminoethylphosphonate binding
                     [Evidence IEA];
                     GO_process: GO:0033223 - 2-aminoethylphosphonate transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     substrate-binding protein"
                     /protein_id="HHS5223927.1"
                     /translation="MKFKKLVSLGVLSTLLLSVITGCSTDSSGSDSKSDSKTKGDLTV
                     YTAIEEDSIEPYLATFKEKYPDIKLNIVRASTGDITARLLAEKDNPQADVVWGVAATS
                     LLVADDQGMLEPYAPKGSEEIESAFKDDKEVPSWVGIDAWMTGITVNTKELSDNNIPV
                     PSSYEDLIKPEYKGLISMPNPSSSGTGYLTVSALIQIMGEEKAWQYMDKLHENIGVYT
                     QSGSAPATSAASGEYPIGISFGYRGIKLKEEGYPVEVVFPKEGSGWDIEANALVKKDN
                     IKEASKVFLDWAISKDAMNEYSKNYAVTTISTGNPIPEGFPKKPLEQMIDNDLKSAAK
                     NREDILNKWISKYDGKTEKES"
     gene            24590..24706
                     /locus_tag="KRH23_000632"
     CDS             24590..24706
                     /locus_tag="KRH23_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter ATP-binding protein"
                     /protein_id="HHS5223928.1"
                     /translation="MDDDINMIAIRPEDIRVEFNRDFKEIIDLKLRPHRYKN"
     gene            24870..25937
                     /locus_tag="KRH23_000633"
     CDS             24870..25937
                     /locus_tag="KRH23_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009897 - external side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0030288 - outer membrane-bounded
                     periplasmic space [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0033225 - ATPase-coupled
                     2-aminoethylphosphonate transporter activity [Evidence
                     IEA];
                     GO_function: GO:0033226 - 2-aminoethylphosphonate binding
                     [Evidence IEA];
                     GO_process: GO:0033223 - 2-aminoethylphosphonate transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     substrate-binding protein"
                     /protein_id="HHS5223929.1"
                     /translation="MKFKKLVSLGILSTLLLSVITGCSNVSSGSNLKSNNKTKGELTV
                     YTAIEEDSIDTYLTTFKEKYPDIKLNVLRLSVGGITARLLAEKDNPKADVLWGVAATS
                     LIILDDKEMLEPYAPKGFDKVNPAFKDDKKVPSWVGIDAWMTGITVNTKELKAKNISA
                     PSSYEDLIKPEYKDLISMPSPASSGTGYLTVSELIQIMGEEKAWQYMDKLHKNIGVYT
                     QSGSAPAILAASGEYPIGISFGNRGIKLKGEGYPVEVVFPKEGSGWEIESNALVKKDN
                     IKEASKVFLDWAISKDAMNEYSKNFAVTTIDTGNPVPEGFPKNPLEQMIDNDLKSAAR
                     NREAILNKWIEKYDGKTEKES"
     gene            26129..26659
                     /gene="rnmV"
                     /locus_tag="KRH23_000634"
     CDS             26129..26659
                     /gene="rnmV"
                     /locus_tag="KRH23_000634"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043822 - ribonuclease M5 activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HHS5223930.1"
                     /translation="MIKEIIVVEGRDDVTAVKRAIDAELITTGGFGFPKGVMERIKAA
                     NERRGVIIFTDPDFAGEKIRKKIASEVPGCKHAFLPREEAKKDGDIGIENATPQSIIA
                     ALNKVRTENTEKRDEFKQVDLIRNGLIGNEEASLRRDALGKILGIGYGNAKQFLNRLN
                     NYGVEREEFIDALKQI"
     gene            26830..27699
                     /gene="rsmA"
                     /locus_tag="KRH23_000635"
     CDS             26830..27699
                     /gene="rsmA"
                     /locus_tag="KRH23_000635"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000179 - rRNA
                     (adenine-N6,N6-)-dimethyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HHS5223931.1"
                     /translation="MDRLSSHNATKEVVQKYNFKFSKSLGQNFLIDSNIIDKILSGAR
                     ITRGDNIIEVGPGIGTLTREMGKIAEKVVAIEIDRNLIPILKDTLSDLDNTEVVNQDI
                     LKVDIQELVKDKLNGGPVKLVANLPYYITTPIVMKFLEEDIPVTDIVVMVQKEVADRM
                     NAIPGTKDYGALSIAVQYYCDTEIVAKAPRHMFIPQPNVDSTVIGLHVRDKRKYDVHN
                     EDIFFKTVKASFGQRRKTLLNSLGGLGFLNKDEIREILKEANIDEKRRGETLSIEEFS
                     VLSNIINTKVSSK"
     gene            27765..29027
                     /locus_tag="KRH23_000636"
     CDS             27765..29027
                     /locus_tag="KRH23_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5223932.1"
                     /translation="MGSKRKFKRDYIILEAKDINFRYKERVLPKAFAKVEVNDEKAII
                     ALYVENLKYVKDGYKAVAIKDDHGLIDLGNIILNEQGRGEFVLDLEDSDDEIKGIALL
                     YERNIPLIGFKGNKLENYEDILFQEVEEEEYEELEEEEDEEIEDNDESDRDEDNEEEE
                     FIIEEYEEDDYEDYWEDDEDIEEGELKARTEVEDSSDEEIEEFNNYKEIENYNRVKVQ
                     EEYIDIEYNEEEEDEEEVFEVNREEDRFVSSKPTKAKKVQKDQNNIEKIKRANGVSQG
                     ESGNKQTSTLLMPRQIKKGLKLFKEVKPFVTDYIDKTRWWKIEINPTTLCGYTMPYLG
                     YLNVLNYTMYSDAVLHSYKYRHYLFGVQYDEYNKRKHYIYAIPGNRNEQPDNGSTGFL
                     RYQACDNRTNSLGYWLCFIDSRQRNIVR"
     gene            29178..30293
                     /locus_tag="KRH23_000637"
     CDS             29178..30293
                     /locus_tag="KRH23_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HHS5223933.1"
                     /translation="MINEQRILNEFLELVQIDSLSLKEGNVAKVLVKKLEEIGCSVVI
                     DNAGEKANGETGNIIATLKGNKEGKKILFSSHMDTVTPGIGVKPIVDEANGIIKSDGT
                     TILGSDDKAGIAAILEGLRYINENNIEHTDIQVVFSICEECGLVGAKNLDYGKIDSEY
                     AFILDSGGSPGEIIVKAPAQDVINVKILGKTAHAGLEPEAGISAIMVAARAIENMNLL
                     RIDEETTANIGIINGGTATNIVTGEVNIIAEARSLKENKLDVQTKHMVETFEKAAKDF
                     GAQIEIDVNRAYTPIDVSEDSEIIKLAKKAFSNLGIEGHTESTGGGSDTNILSKNGIE
                     AITLGIGMKNAHTLSEHIAIKDLYDSAKMVVEIIKEA"
     gene            30479..31375
                     /locus_tag="KRH23_000638"
     CDS             30479..31375
                     /locus_tag="KRH23_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HHS5223934.1"
                     /translation="METRYEEANKITIQSILWNVVLTIIKVIAGVIGNSSAMIADGLH
                     SASDIISSIGVLIGNYVSSRPGDREHNYGHEKAETLVSFVLSILLIFVSITIGIEAIK
                     SLFNLDALSVPSILPLVVSVISILIKEYQYRITIKVAKKINSPALKADAWHHRSDALS
                     SVAAFIGIGGSILGFKPLDPIASVVVAIFVAKVGISILISSVNELMDVSVDEEEIKEL
                     KFIVADTEGVKNLGDIKTRKHGAMAYVDLTICVDENLTVKQGHDIATKLEKHIIKHME
                     FVKGITVHVEPCTNCQGNKCNN"
     gene            31445..32242
                     /locus_tag="KRH23_000639"
     CDS             31445..32242
                     /locus_tag="KRH23_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5223935.1"
                     /translation="MSKKRKLKKKAAILIGVVVFFIIYFISFRIGINMEKDKSEVPKK
                     VEKEEEDNRSLRTQIKEKKKVYISDKNIENIKIEEDMWDEIKLFFSDFKKVRNTTSSY
                     EAVYEGYSDDGVKFSTDLNFFRVYTVNKEEYYKVPVSSKDAFKKLLDESIYTSFDLLS
                     HYKDWKEVTITHGKEIKKVHRWKFDDLAHKMISKRVVGKVQPEKSKERSDYNFTINIK
                     GDNFDVKVDTMGKDYVKVTSKKNVSYYEVHISLFDYLKNEIFEIGKK"
     gene            complement(32298..33650)
                     /gene="murC"
                     /locus_tag="KRH23_000640"
     CDS             complement(32298..33650)
                     /gene="murC"
                     /locus_tag="KRH23_000640"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008763 - UDP-N-acetylmuramate-L-alanine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HHS5223936.1"
                     /translation="MNIHFIGIGGISMSALAEICINKGYQVSGSDSNESYLLDKLRDQ
                     GATIYIGQKKDNISDDVNMVVYTAAVHPDNEELVAAKEKNKLVMNRATFLGQIMREYK
                     NSIAVSGTHGKTSTTSMLSTIFEYADLDPTILVGGNLSMIGGNVKIGNSNHFITEACE
                     YVDSFLNFNPKISIVLNVEEDHLDYFSGIDEIKASFNKFGKLLPPEGYFIINGDDENI
                     DDILYDVKATIIKYGRDSDNDAVIKDIHFDSSGHGIFRIEYEGRDLGEFELSVYGLHN
                     IYNASSAIMAALVSGIDLETIRKNIKIYKGVGRRFETKGYYKNALVVDDYAHHPTELK
                     ATLAAAKKLKKSTLWCIFQPHTYTRTKSLLGEFSEAFYAADKVIITDIYAAREKDPGD
                     IHSKDLVEKLYQNNVDAIYIKEFEDIVKYLRENVKDNDLVITAGAGPIYKVADLLVEK
                     "
     gene            33869..34747
                     /gene="purR"
                     /locus_tag="KRH23_000641"
     CDS             33869..34747
                     /gene="purR"
                     /locus_tag="KRH23_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA];
                     GO_process: GO:0045982 - negative regulation of purine
                     nucleobase metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HHS5223937.1"
                     /translation="MKFKRTERIGAIVKILSDNPNKIYTLSYFTNQFNAAKSTISEDL
                     LVVKNVFEKLHLGKVITISGAAGGVKYIPKTSIAENAEFLMELCERICDKSRILSGGF
                     LYLIDLIYDPTIAAKIGKIFASNIEYVDADYVVTMETKGIPMALMTAKAMNLPLVIIR
                     KDIKVSEGPTLSMTYVSGNSSKVESMSLPRKALKPDSKVIIIDDFMRGGGTIKGMVDL
                     MNEFGAEVIGTGVFISTTNPSEKMVKDYISLIQLDVNGDKIVVEPNLKTFKDEYRNED
                     LDEEEDSEFEFEIDED"
     gene            34903..35181
                     /gene="spoVG"
                     /locus_tag="KRH23_000642"
     CDS             34903..35181
                     /gene="spoVG"
                     /locus_tag="KRH23_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0030435 - sporulation resulting in
                     formation of a cellular spore [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="septation regulator SpoVG"
                     /protein_id="HHS5223938.1"
                     /translation="MKITDVRVRKLTEEGKMKCIVSITFDNLFVVHDIKVIEGHNGLF
                     IAMPSRKVGEGNFRDIAHPINAEMRQVLEDAVLQAYHEALVQWEVAAE"
     gene            35394..36773
                     /gene="glmU"
                     /locus_tag="KRH23_000643"
     CDS             35394..36773
                     /gene="glmU"
                     /locus_tag="KRH23_000643"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0003977 - UDP-N-acetylglucosamine
                     diphosphorylase activity [Evidence IEA];
                     GO_function: GO:0019134 - glucosamine-1-phosphate
                     N-acetyltransferase activity [Evidence IEA];
                     GO_process: GO:0006048 - UDP-N-acetylglucosamine
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HHS5223939.1"
                     /translation="MNFKAIILAAGKGTRMKSKYPKVIHKVCGKEMVNHIIDVSKKSG
                     VKDTVVILGHEAEVVKEKLAEEIIIAMQTEQLGTGHAVKMAKEYINDEDTIVVLCGDT
                     PLIKEETLKRLFEYHIENKYHATVLTTRVGNPTGYGRIIRDKKGDLLKIVEQKDANSE
                     EKMISEINSGIYCFNGKSLREALDLLNNNNSQGEYYLTDTAKIMRDKGLKVGAFAGST
                     IEELMGVNSRVELSKAEEIMRRRINESHMVNGVTIIDTNSTYIESDVMIGNDTIIYPG
                     VMLQGKTRIGSDCIIGMNSSITNSEIGDGTEIKNSTIIDSKVGENSTVGPYAYLRPKS
                     DLGNNVKIGDFVEVKNAIIEDGSKASHLSYIGDAHVGKNVNIGCGVVFVNYDGKNKFK
                     SIVKDNAFIGSNSNLVAPVVVEEKGYIATGSTITHDVPDGALAIARERQVIKEGWVEK
                     KNQKDDQSK"
     gene            36868..37818
                     /locus_tag="KRH23_000644"
     CDS             36868..37818
                     /locus_tag="KRH23_000644"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0002189 - ribose phosphate
                     diphosphokinase complex [Evidence IEA];
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004749 - ribose phosphate diphosphokinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0006015 - 5-phosphoribose 1-diphosphate
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009156 - ribonucleoside monophosphate
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009165 - nucleotide biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HHS5223940.1"
                     /translation="MNTSGSEIKIIAGNSSKELAQKIADYIGVSVLDCEVGTFSDGEI
                     CVNMNETVRGCDVFVVQSTNSPVNDNLMELLILIDALKRASAGRITAVIPYYGYARQD
                     RKAKARDPITAKLVANLITAAGADRVLTMDLHAAQIQGYFDIPLDHLLGGTILANYFN
                     EKKIEDLVVVSPDLGSVTRSRKFANTLNGEVPIAIIDKRRPKANVCEVMNLIGDVKGK
                     NVILLDDMIDTAGTIVNAANALKEFGAKDVYACCTHGVLSGPAIERIANSEISELIVL
                     DTIQLPEEKRIDKIKIKTVAPLFGDAIRMIFSNESVSKLF"
     regulatory      38657..38742
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF01786"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cyclic di-GMP riboswitch class II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01786"
     gene            38904..39419
                     /locus_tag="KRH23_000645"
     CDS             38904..39419
                     /locus_tag="KRH23_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0015627 - type II protein secretion
                     system complex [Evidence IEA];
                     GO_process: GO:0015628 - protein secretion by the type II
                     secretion system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HHS5223941.1"
                     /translation="MKLKKNKKGFTLVELLVVIAIIGILAVVAVPALFSNINKAKVAS
                     VESDYSSVKSAALSYYSDTNKIPVTPDGQTGLSVLETYMESLPDKADIGGEYKLIKVG
                     SKLVLQIGTNTEGVTLTEAQSAKLLSDIGENKIYTNAALSAKLTSTTKVNNEALYIVL
                     IDNIVMDQQGA"
     gene            39548..41224
                     /locus_tag="KRH23_000646"
     CDS             39548..41224
                     /locus_tag="KRH23_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GspE/PulE family protein"
                     /protein_id="HHS5223942.1"
                     /translation="MAKKVRIGDKLVEKGYITEEQLKWALSEQKNSGKRLGEFLVQEG
                     LIDSNLLISVLKELLDIESIFLEGTEIDTLATKMVPENICKRYTVFPFKIDGNKICLA
                     MSDPQDREAVQDVRRMSGKDVEIFISSTEDINKAIGHAYAHSEINKAMTEYNKNRTGG
                     VRETVILEEDVNAAPIVRLVNNILENAVRMEASDIHIEQSENYMRVRFRIDGMLREYM
                     RMNSAPYKAVISRIKIMSDINISEKRIPQDGRIYLKVDNKPIDFRVSTMPTNRDEKIA
                     MRVLDKSNFMVSKEVLGIDEHGSKIYDELINTPYGLILVVGPTGSGKTTTLYSMLNQL
                     NTENRNLLTIEDPIEYELPGVNQSQINEKAGLTFASGLRAFMRQDPDIIMVGEIRDTE
                     TAEIAIRASLTGHLVLSTLHANTAVGAISRLLDMDVESFLITSSVLGVISQRLTRKIC
                     EHCKVSYEADIGEKKALGIDVNESVTIYRGKGCERCNNTGYKGRLGIFEMLEITPEIK
                     ELIDSSANQREILKMARKQGMVSLKEDIVKKVLNGKTTVEEMIRIILMTD"
     gene            41236..42444
                     /locus_tag="KRH23_000647"
     CDS             41236..42444
                     /locus_tag="KRH23_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0015628 - protein secretion by the type II
                     secretion system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HHS5223943.1"
                     /translation="MKSFKYTVIKEDGKKQTDVIEANDFNEARNLLRKRNLRVIEIKE
                     SKNKNIRLSSRKRKKDLGADQISHFCRQFAIIVSSGINSISGLETLARRSTNITLREE
                     INRIVAEIKVGSTIADSMLSSKSKFPKLLGAMVATGEATGKLDEVLKSMASFYASEHR
                     VKQKLRNAATYPLIVLISSFIMIFIFTTFMVPKMINSITTVGATLPLITRIVMGFGMF
                     MKKFWIIVLLVIILFIYQFKKYLKTSVGRAHKDRVINKIPVLGKGINCMVATRFSRAL
                     YLFVSTGYPLVQGLDYIIDSVNNTMAEKILASAKDGITRGEGLAENLERYTYFDSVLV
                     QMIAIGEQTGELENISRQMAEFYEYESEIYLNRMASMIEPVLIIAVGIIVAILVVSIF
                     MPMLSIYDAM"
     gene            42459..44171
                     /locus_tag="KRH23_000648"
     CDS             42459..44171
                     /locus_tag="KRH23_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PilN domain-containing protein"
                     /protein_id="HHS5223944.1"
                     /translation="MNKVYVSYYGDSISIVEGRYKHDKDKFYVKNFNVFSIEDIAQDF
                     SKEKYALLRYALENVKLKSRHVVFCLNTRDVILKPQKLPNMDKKDLDGFMKLEMDEMM
                     ALESDEYVFSYEVSSETPDNSDGDESSLNLIIGAIQKEEVNAIVEIMHEFDLVLDRID
                     TLSTAYLRMLKNLDYNDIMVTNISDNSTIINIYKKDTLFISDNIPIKITAKDMDMQLL
                     NVVEESKGLMNYYSSRNFGKVTDTILILGKRYSNKLIYETFSSAFSSYVSQGLTEIMD
                     ISDMITGDIDEDDINSIVELLGSMIEPKGKRDFENINFLPMDILRKQIKAKQMKNILK
                     IAPIVILILAIPYLCLIFSNNLANKELENVNGEIRNIESAYYQIGNIEKMIQSKSEEI
                     KVYDMLIGKKVKWENLLDDIDKNTPSKVELTSLSTTYQNLGTNNKADNSKSNKTTTDK
                     SSNNETKSSTKSDSNGDKTDNDLNEDKTTNVSEALIGNSETNSNNTDKDDKTPLYDKI
                     PNVINIEGNAKDSSYVGQFLYKLKGLYYFKDVKLHSIKSNAEDSNYTFSMTLYLKEGV
                     LTNE"
     gene            44164..45072
                     /gene="pilO"
                     /locus_tag="KRH23_000649"
     CDS             44164..45072
                     /gene="pilO"
                     /locus_tag="KRH23_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0043107 - type IV pilus-dependent motility
                     [Evidence IEA];
                     GO_process: GO:0043683 - type IV pilus assembly [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 4a pilus biogenesis protein PilO"
                     /protein_id="HHS5223945.1"
                     /translation="MNKDIFKKDIKDIFKMEVSLKGILIKVIILLAILSYGYFGLYPQ
                     YQKYIATKNSVKQATEKLNIYKEKTALMPKYEKQLEEVESELKEKSKNLLYDMQDGLF
                     LIGLDKKMKAYNIDLTSYDVGNVKEYEHFYGISTTISVRGDYRNVKKLMAYLEEQKNV
                     TQILDYTMTSYIEPEKEEEETTNNKDLIKNVNINKDTKIYWVEGENKWHLYKDCPLIK
                     EGEILKNDKLLDRSTNYLCNTCVLRAATEKEAKKEVVAPKAEGVVDATFKFIMYTKEN
                     TTMILDTDNPSSWRPGKYNPFKSSAK"
     gene            45099..45665
                     /locus_tag="KRH23_000650"
     CDS             45099..45665
                     /locus_tag="KRH23_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0015627 - type II protein secretion
                     system complex [Evidence IEA];
                     GO_process: GO:0015628 - protein secretion by the type II
                     secretion system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PulJ/GspJ family protein"
                     /protein_id="HHS5223946.1"
                     /translation="MSLYKNNEKGLTLLEVIIAVFILTIVLSISYKVFNGITSAVKKQ
                     QIITDAQVNINLINKYLNRDLENCKELTKTGSGNNYEYNIEMPDNVVKYEVSIETKKN
                     TEVYSVTRIQNNTIDTENEVREEIIYNQPLVQNNKEMKETPFKIEKQTGKSIYTVSIY
                     YNESVQESHKNSNLNNKTYTFDVMSRIG"
     gene            45702..46229
                     /locus_tag="KRH23_000651"
     CDS             45702..46229
                     /locus_tag="KRH23_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type IV pilus modification PilV family protein"
                     /protein_id="HHS5223947.1"
                     /translation="MSKKNSERGFSLIEVLVAMAIMGIVLFAFFNIINTNNKANTKND
                     TDITSLNYVQSEIENLREKIKSGEFDFDSLDKLEDGTVVYEKLIDKSKKVVYDKVLSE
                     GDVSLYDTPYEKITTIKDEDGNLIDKGNITNKIKTIVEDKSGQIYKIAVTGKSMNDYS
                     SKKEVKIVTEIFKDK"
     gene            46250..47788
                     /locus_tag="KRH23_000652"
     CDS             46250..47788
                     /locus_tag="KRH23_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5223948.1"
                     /translation="MRKWNKFKSERGAALVLVLVVVALLSIVGLIFSNQIANRIKSTK
                     TTNEGIQAKYLAETCVENSIDKAYEKLYDELEKMDNEFKSENQEKSISRSKLRNISDE
                     DFNNQDEENIEAERLGYMNNINFYLNKASSDLEKASMELKKLYDLDMLDYRDIEYVDA
                     NIISHRDSILEICKNYTSGDISKINEYILEEDIDSTTLIEAKLVNNDILLKMFLEENK
                     IENEHLNSAFSHTYKALDNISLAMQNMIEYRHTFHIDEPKVEVSNGIPDSQQYYELIQ
                     NPIINSMEYIWNSKWDTLENLLEILPDQTQGFNSLRVHLRNNVRKFEKLSDNISSGKK
                     NTAKNFLKYKELLYEISDQCNQLKSMSYEKIPVKYDNMALITTFDYIQNELLAEIKCR
                     LKELKPQEIDKTEGITIKIPFYKADYDMTKEGWPKLKENGSGAELSLMVTGDKDGIKE
                     VEVTDGKKNIIGLGVEENSNSKYKVDAIVNFNLNIDTNVVGNYDIKDKILINHDISSY
                     KKVN"
     gene            47888..48970
                     /locus_tag="KRH23_000653"
     CDS             47888..48970
                     /locus_tag="KRH23_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0043107 - type IV pilus-dependent motility
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type IV pilus twitching motility protein PilT"
                     /protein_id="HHS5223949.1"
                     /translation="MYIYDLLEQGIRLNASDIHITVGTNPVARVKGGFVKLSEQILTS
                     EVTMQMAKDIAGESMFKVIEEHGEADFSASLKTGERFRVNAYRQKGNYAIAIRTITAE
                     IPTFEKLGLPESIKSFTEKHKGLVLVTGPTGSGKSTTLASMINIINEKQQKHIITLED
                     PIEYVHHHKQSLVNQREVGTDTESFHSALRAILRQDPDVILIGEMRDPETVSIALTAA
                     ETGHLVFSTLHTVGAAKTIDRIVDMFQPSQQQQIKTQLSTVCEGVVSQQLLPTADGKG
                     RIAAIELMFATPAIKNLIREGKTYQIPNMIQTGVKVGMKTMDQDLMELYKNGKITKDM
                     ALSRCTDQEFMTRMIGGVNYNGYYNR"
     gene            48951..49733
                     /locus_tag="KRH23_000654"
     CDS             48951..49733
                     /locus_tag="KRH23_000654"
                     /EC_number="3.4.23.43"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HHS5223950.1"
                     /translation="MDIIIVNLYVFMVGIVFGSFFNVCIFRIPEGISISRPPSHCMSC
                     NTRLKPIDLIPVLSYLMSGRKCRYCYEKISSRYAIVELITGLLFLTVFMLYGISTSTI
                     YYLVLVSLLIIITFIDIDHFIIPDKILVFGAMFSMIFNLLFKEIPVKDSILGVFICGG
                     SVWIIVLLIEFVIKKECMGGGDIKLFAMLGFYMGVKNGLLTALLSVYVGAVYGICVII
                     ISRIKGKEYNSVIPYGPFISIGALITILCGKQLLELYFSMVI"
     gene            50015..50485
                     /locus_tag="KRH23_000655"
     CDS             50015..50485
                     /locus_tag="KRH23_000655"
                     /EC_number="3.4.23.43"
                     /inference="COORDINATES: protein motif:HMM:NF013632.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HHS5223951.1"
                     /translation="MVLIPFLIIISIVDYYTIYVYDITIVSGIIVQGIIFLVFFNMVQ
                     FDYINHIFGLLIGFIIPYIIAKLTKGLGYGDVGLYSLCCFALGNNYGFYVIVLSFILA
                     FLFFIILYITKIFKDVDIRKQIPFTPFISLSTILIIFTEYNIFNFYYNLLYKFI"
     gene            50499..51059
                     /gene="pth"
                     /locus_tag="KRH23_000656"
     CDS             50499..51059
                     /gene="pth"
                     /locus_tag="KRH23_000656"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004045 - peptidyl-tRNA hydrolase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HHS5223952.1"
                     /translation="MYVVVGLGNPGKKYEKTRHNVGFDVIDILAKEYNISVTKIKHKA
                     LIGEGRVGTEKVLLVKPQTYMNLSGETLIDIYKYYKVDLSNIVVVYDDIDLEVGKIRI
                     RKKGSGGTHNGMKSITKCLGSNDFPRVRVGVSKPEAGQDLADFVLSRFRKEESDNINE
                     ALEKAADAIDSIIRENIDMSMNKYNG"
     gene            51076..54462
                     /gene="mfd"
                     /locus_tag="KRH23_000657"
     CDS             51076..54462
                     /gene="mfd"
                     /locus_tag="KRH23_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HHS5223953.1"
                     /translation="MNDVFLYPLQNSKEYKDIINCIKNTKGSLLVNGLLPVQKPHISY
                     SIFNDLSRQMIFITSSDLEAKKVYEDLSFYMEDKVEYLGFQDIYFYHLDAKDRNEEAK
                     KLKVLLKLANKEKIILVTSIEAVLRKYIPKQVLLDSVSHYKVGDSLDLEKLTEKLVSL
                     GYERVSKIEGFGQFSIRGGIIDVFSLEYTNPIRMELFDDEIDSIRTFDVYSQKSIDKL
                     QQFSITPSREFIYPEKTTDALVKLKKETTKNTDEGTFQNIDYISSKTYFEGAENYIDY
                     IYPEENKSIFTYLADDAIVFINDITRLKERCENYINEFRENYKLNLERGLAIKNQGKL
                     LYHYTDLEYLVKDKSVVLNSLLPKSINNFSIKSIINFESREVPTFNGKVDLLVEELNR
                     LKYNGYKIILATNTLERANKLGKDLLDKGLETTISKDRDIEIKSSQVIIVPAHINSGF
                     QYKSIKFVVITDNEMIGVYKRASKTSNKKVKKGKKIESFLDLSVGDYVVHENSGVGRY
                     TGIEQITVNAIKKDYMKIVYQGGDNLYVPIDQMDKVQKYIGAEVEKVKLNKLGTNEWT
                     KAKAKVKKEIEDMTKDLIELYAKREKIQGYKFSKDTPWQAEFESLFPYQETEDQLKAI
                     EETKKDMESSKVMDRLVCGDVGYGKTEVAIRSIFKACMDQKQVAVLVPTTILAQQHYN
                     TFKERFENYPLRVEVLSRFKTPKQQKQIIEDAKKGLVDILIGTHRIISKDINLPNLGL
                     VVIDEEQRFGVKHKEALKKIKSTVDVLTLSATPIPRTLHMSLSGIRDMSVIEEPPQER
                     HPVITYVTESKESVIQDEIERELSRGGQVFFVYNRVEHIEEMASMIQKLVPDARVAVA
                     HGRMTSKSLENIILGFLNKDYDVLVCTTIIETGMDISNANTMIIYDADKMGLAQLYQL
                     RGRVGRSSRQGYAYLLYEKDKTLSEIAEKRLKAIREFTEFGSGFKIAMRDLEIRGAGN
                     ILGSQQHGHMAVIGYDLYVKMLNDAIKKVKGEPIVEEIDVEIDLSVNAYIPDNYIKDE
                     LIKIEMYKKIASIENKEDMLDIQEELEDRFSDIPKPVQTLLTIAYIKSLCKILKIEKI
                     RQLKDEILLVPITKYRTKQKIGYNIVTELEELLEKMCKVK"
     gene            54493..55488
                     /locus_tag="KRH23_000658"
     CDS             54493..55488
                     /locus_tag="KRH23_000658"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="foldase protein PrsA"
                     /protein_id="HHS5223954.1"
                     /translation="MKKVITLVIAMILVVSVTACSSSKGETVATVEGTKISSDEFKKT
                     IALYKDSMEQTYGKDIWDKEVEKGVKYKDKFKDLILDQLITTEVIYSQAKKDNLLPKK
                     EDVEKSFKELKDAMGKDEKYKEQLKKLGIDDEFLRDQQEKDLAMQNYQSNFAKKTKIS
                     DEEMKKYYDTHKDEFKKDEVEASHILLKTVDDNNKPLSDKEKAEAKKKAEEALKEVKS
                     GEDFAKVAKKYSQDTSASDGGKLGFFSRGQMVAEFEDAAFSMKKGEVSDLVETQYGYH
                     IIKVTDRINEQTSFEDAKETIKDQLLKNKYQEQIEKLTKEAKVEKDEKVINKITI"
     gene            55612..56151
                     /gene="spoVT"
                     /locus_tag="KRH23_000659"
     CDS             55612..56151
                     /gene="spoVT"
                     /locus_tag="KRH23_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein T"
                     /protein_id="HHS5223955.1"
                     /translation="MKATGIVRRIDDLGRVVIPKEIRKTLRIREGDPLEIFTAKDGEV
                     ILKKYSPIGELNEFSQEYAETLAEVLGYGVLITDLDSIIAVSKLPKKDYKEKSISDEL
                     EAIISERTVKYSKDKNILPLFKEDQKEYTSQVIMPIISASGDCIGSIVVVSKDKDTIA
                     ESEEKSLKIAANFLGKQVQ"
     gene            56271..57884
                     /locus_tag="KRH23_000660"
     CDS             56271..57884
                     /locus_tag="KRH23_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative polysaccharide biosynthesis protein"
                     /protein_id="HHS5223956.1"
                     /translation="MNNNKNKDSFLKGALILGLAGVIVKIMGGFFRIPLGNMIGSEGM
                     GYYQAAYPVYTLFLTLATAGFPTAVAKLVSEKVAIGNFKGANKIFKVSHTVLFITGII
                     SFCILFFGADYIVTNVMKNPGALYSMKAIAPALLFVPAMSAYRGYFQGRQDMTKIAVS
                     QVAEQFFRVVLGLTLAYLLMKSLGQTFGAAGAISGATIGSIASMLYLVFAYMLGRKER
                     RAEIDASQRFKDERVSYIFKKLLTVAIPITIGASVMPLVNMIDNVIVIRRLMEAGFTY
                     KVANSMFGQLTGMAMATINLPAVITTAMSMSLVPAISKAYALGNKSKARKDTKSAVKV
                     TLLIVLPCAFGMASLAIPIMGLLFPHEPSSVGTILFTLTPCVLFLGLIQTLTGIIQGM
                     GKPIVPVIALCVGMLCKIVISYTLTGIPDINVLGSAFGTVTAYFVAAMINLLYVKKHM
                     NVNFSKKEFIIKPFITVMTMFIMVKLSYGALVGFLGNSISTIIAICVGGIVYVVVILG
                     IGGIKKEEILTMPKGDKLYKLLKKVKLIR"
     gene            57991..59439
                     /gene="mazG"
                     /locus_tag="KRH23_000661"
     CDS             57991..59439
                     /gene="mazG"
                     /locus_tag="KRH23_000661"
                     /EC_number="3.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside triphosphate pyrophosphohydrolase"
                     /protein_id="HHS5223957.1"
                     /translation="MGKISIVGLGPGDYSLISQGVLESLINSPKVFFRTEKHPIIDKL
                     KETIQYTSLDYFYEKEENFDNVYLKISEFIIEESAKGDLVYAVPGHPRVAEKTVSIIE
                     RLANEKHIAVEILPSMSFVDAMFTYLAIDPSEGFKLVDAFEIENSYIDLDTSMIITQV
                     YDKFIASNVKLKLMEHYDYNQEVCIVNGAGVKDLESKKFIKLCELDRNENFFDYLTSL
                     YIPKSSKKMYNTVHDLEIIVNTLRSPSGCEWDKKQTHQSLKNSVIEEAYELCNAIDNN
                     DIDEMVEELGDVLLQVIFHCQIGNEEGYFDLKEVVNGICKKLIHRHPHIFSGAKLDMS
                     KFEKTWEELKKEEKGESTITDGLRRIPKHLPALMKASKVQHKAALVGFDWDNVEDVFK
                     KIEEEYQELLDEHRVGNIKYIKEELGDLLFSIVNLARFLDIDSGEALNCTTEKFINRF
                     DFIEKSAMNLNKKLEDMTLEEMDEFWNQAKKQ"
     gene            59528..59806
                     /locus_tag="KRH23_000662"
     CDS             59528..59806
                     /locus_tag="KRH23_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HHS5223958.1"
                     /translation="MNKAELVSKMAEKSGLTKKEAEAALNAFMSSVQDALVNNEKVQL
                     VGFGTFETRERAARQGRNPRDPEQVIDIPASKAPVFKAGKGLKDIING"
     gene            59878..60120
                     /locus_tag="KRH23_000663"
     CDS             59878..60120
                     /locus_tag="KRH23_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HHS5223959.1"
                     /translation="MRLDKFLKVSRIIKRRTVAKDACDKGIVTINGKVAKSSSEVNIG
                     DTLEIQFGEKKMKFKINEVKEHVLKNDAKEMYEILE"
     gene            60182..60436
                     /locus_tag="KRH23_000664"
     CDS             60182..60436
                     /locus_tag="KRH23_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YabP/YqfC family sporulation protein"
                     /protein_id="HHS5223960.1"
                     /translation="MEQNITLKDRSKLVISGVEHIYSFNDKRVELKTSVGEMVIEGEN
                     LDMSKLSIDENIISIDGTINSMVYAKPKKPQESFLKKVFR"
     gene            60437..60970
                     /gene="yabQ"
                     /locus_tag="KRH23_000665"
     CDS             60437..60970
                     /gene="yabQ"
                     /locus_tag="KRH23_000665"
                     /inference="COORDINATES: protein motif:HMM:TIGR02893.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0034301 - endospore formation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="spore cortex biosynthesis protein YabQ"
                     /protein_id="HHS5223961.1"
                     /translation="MIPFTQDVSIFYATIYGGILIGVLFDFYRGLRGNFKFINYFAII
                     FDVLFWFLATVIIFVTINLTEFFDLRYYHFVALFIGFILYYNTISKIVLSIINKIIRF
                     VRNSFKKVTHYIVSFLNNLYYVIIYSLHLLFDIIFYIPNIFIATRKSIKRKSNKKLKN
                     KKKSKPKKKKNKTKKRV"
     gene            60976..61260
                     /locus_tag="KRH23_000666"
     CDS             60976..61260
                     /locus_tag="KRH23_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsB family cell division protein"
                     /protein_id="HHS5223962.1"
                     /translation="MNLRKKFSGQIIVVSLFLGISIFSMMTGFVFEYTKAKEYKKEIA
                     SLNKQLKKTEIQINSLKKDEKSYEGDLEDIARKRLNMVKPNETVYVDINR"
     gene            61373..62293
                     /locus_tag="KRH23_000667"
     CDS             61373..62293
                     /locus_tag="KRH23_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ppx/GppA phosphatase family protein"
                     /protein_id="HHS5223963.1"
                     /translation="MKVGAIDIGTNSMRLLIADYRDGNFINRKKFVNTTRIGYGVDSK
                     GYIKEDAIKRNIKALKEFSDKCNDEKCEKIYCMGTSALRDSKNGDYFVKLAKEETGID
                     VDIVTGIEESNLGFKGVLEGIQGDDTIIVIDIGGGSTEFIVGDSEGIKFNKSENVGAL
                     RMTERFLKHDIIEDEEFEAMSSFIYDEIDKTLNHIKDRGLKTLIGIGGTITSLSAMNQ
                     ELEIYSMEKIHNSKIHKKEIEEILQKLIKMTLSDKKNLKGLQEKRADIITAGVKILNI
                     IMEKLEIEEITVSEYDNLEGLICQKSKKMY"
     gene            62383..64755
                     /gene="spoIIE"
                     /locus_tag="KRH23_000668"
     CDS             62383..64755
                     /gene="spoIIE"
                     /locus_tag="KRH23_000668"
                     /EC_number="3.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004722 - protein serine/threonine
                     phosphatase activity [Evidence IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein E"
                     /protein_id="HHS5223964.1"
                     /translation="MQRSVAVVKNKTVKPNVIKLISGYIDFTTAAFAVMGFLLSRSII
                     VDSVAPLGIAFFICASKIDKYKIPVFISTLLGILLSSNDFGNVAKYAVCLTIFMAMNK
                     KLKLSDSIAKVAFIGAIILLPISMGQAFFSNRYVYGLLIAGVEAIIMFISIYVFSYGI
                     GLMANVNNRMSVRTEEAISISLLLTFSIMGIGDISLFGISIRTILSTVLILLTSIVGG
                     ATMGASSGVIIGVASILNNMTSAVYMGIYSFSGLISGAFNKINKYFCILGYILSWTII
                     YLYTSGITSNMMQLRDILLGCLIVLVLPERLFNKIEKLIKSNVASNEIVYDYIMRSKN
                     LTNSRLNSIYKTYDDLADTFDKIREKDKVLDQRDIANVIDMIHNDECKSCSMRRMCWE
                     SRFNHTYTMIYNILEKIEEKGELSLNDIPKNFRKECMKPESIVKISNHYYKMFVLDYD
                     WSVKFSESRKLIANQIRSISKSIKSLSQDLEGDIMLDIEKEKNIYEQLERYDITVDKV
                     SYLTKSNSEFEISIEKKTCHDGCMCEDKIVNIISDLVGENMSVRKIGCHCLGGKCKAT
                     FVKSQKYKAVTEVSAMSRDGHILCGDNYTYMEINDGKYMMAISDGMGKGKKAYEESSA
                     TIDILEKMIDAKIKDEIVIDTINNMLLLKSSEEMFSTLDLGILDLKRGCLETIKMGAC
                     STYIKREDGEVDLISSSSLPVGILSDVKIDRKNVKVKEGDYVIMVSDGIVDAGRNNNL
                     GDNWLIYFLKNIETTNPKEISNLILDRALELQALQIEDDMTVLVTKICTK"
     gene            65106..66998
                     /gene="pepF"
                     /locus_tag="KRH23_000669"
     CDS             65106..66998
                     /gene="pepF"
                     /locus_tag="KRH23_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HHS5223965.1"
                     /translation="MNRKLCKAIIPLFISIFCMLIISIKADQGYQKNNDRAITVMNNN
                     DTEDDAEKKQEIDYEKTCWNLQSLFKSDDQWKKELKSFDKDTKELKNYIGKVTKSPTH
                     LSFALNIKEKLDIRLNKLSAYVKLKQDTNKNSYKYLDMNDSMSKSYGNYMGICSDLEL
                     EILKLSNKDYKKIISNKNINRKYGAYLRDIRRNKVHYLDDKSEDILSKVSSISSLPSQ
                     VYELFRNMDRKTNLTPAQYASELESSDRENRKKAYQDELITYNDNINTIAGLITGQVK
                     KNIFYSQERGYESSLEMYLESDNVDEKVYNNLIRTVNSNMDSLHKYIDLRKKVLKLDK
                     VHSYDMFVPMVKAVDNNINYEKAQSIVYSALSPLGKEYNDVVYKAFNEKWIDVYSHEN
                     KVSGGYCLSVYENHPYILLNYNNSLGSVSTLSHELGHAVYEYLSSKNQNYFNSNPSIF
                     THEVASTTNEALLYEMLIKEAKGNDEKAYYITQYLDLIKDTLYTQTMYAEFEKTIHEL
                     VEKGKSVNALVLNDVWGQLLKKYYGQSYELDQLSKVGWARIPHFYNSFYVYKYATGCS
                     AGVSFAQDILKNGSDNYMSFLKKGSSDYPINLLKSSGINLTNTKPIENTIKKFDSLVA
                     ELEKLL"
     gene            67112..68077
                     /gene="galU"
                     /locus_tag="KRH23_000670"
     CDS             67112..68077
                     /gene="galU"
                     /locus_tag="KRH23_000670"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003983 - UTP:glucose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0006011 - UDP-alpha-D-glucose metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HHS5223966.1"
                     /translation="MQVKVKKAVIPAAGLGTRFLPATKAQPKEMLPIVDKPTLQYIIE
                     EAVASGIEEILIITGRNKKSIEDHFDKSVELELDLEKKGKKELLEVVQNISNMINIHY
                     IRQKEPKGLGDAIYCARHFIGDEPFAVMLGDDIVDNDVPCLKQLTDAYEEYRTTILGV
                     QKVNQEDTNKYGIIEAKNIEGRVYKVKDMVEKPESGKAPSNIAILGRYIITPEIFDIL
                     KDLPPGKGGEVQLTDALKILSKKEAMYAYNFEGKRYDVGDKLGFLEATVDFALKKEDL
                     KEDFIKYLKHVCSEFDKNNNVLYNNTDEKIDLIEVNEARELEIQK"
     gene            68577..70181
                     /gene="rho"
                     /locus_tag="KRH23_000671"
     CDS             68577..70181
                     /gene="rho"
                     /locus_tag="KRH23_000671"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008186 - ATP-dependent activity, acting
                     on RNA [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HHS5223967.1"
                     /translation="MRRIFLILDDKVLEGLGSKTLVELREIAKELKIKSITTYKKNEL
                     IEIINSKSKNEEKVNEETKEKNEDIKEDIKNRKENIERESIEKEVEYKSPTKSYNKKE
                     IDTQNISQNQEHRNQRNDYNKTTSVNDSNKSSNISNRMVRNNNKNYYMPKQVDESKIV
                     DEFNTSKEDEVVGVLEILPDGFGFLRGSNYLSTEGDVYVSPSQIRRFNMKTGDKIKGI
                     TRHPKSGEKFRALLYVQKINDENPDTAIQRNAFETLTPIFPEERLTLETNRNEIATRI
                     IDLISPIGKGQRGLIVAPPKAGKTVLLKSVANSIAKNHPNVELIVLLIDERPEEVTDM
                     KESIEGDVIYSTFDQVSSHHVKVAEMVLNRAQRLVEHGKDVVILLDSITRLARAYNLT
                     ISPTGRTLSGGIDPGALHGPKKFFGAARNIRQGGSLTILGTALVETGSRMDDVIFEEF
                     KGTGNMELHLDRKLAEKRIFPAIDIYKSGTRRDDLLLDDEEKTALWRLRREMSNNSVM
                     EITDKVIELIKRTKDNKEFVKSIKNL"
     gene            70334..70534
                     /gene="rpmE"
                     /locus_tag="KRH23_000672"
     CDS             70334..70534
                     /gene="rpmE"
                     /locus_tag="KRH23_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018591942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L31"
                     /protein_id="HHS5223968.1"
                     /translation="MQKEIQPKYNPVEVRCACGNTFVAGSTKDEIKVEICSECHPFYT
                     GKQKNIEKGGRIDKFKKRFKMD"
     gene            70679..71572
                     /locus_tag="KRH23_000673"
     CDS             70679..71572
                     /locus_tag="KRH23_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1385 domain-containing protein"
                     /protein_id="HHS5223969.1"
                     /translation="MAKQAVGGQAVIEGVMMQSKDKRAVAVRKSDGEIALKEDRIKSW
                     VRDKNIDKIPFVRGSFVMIDTMIQGIKSLNFSSEFFMEEAEEDKFDLFIKKIFKDKAN
                     DIIIIFSLVIAMLLSAGLFIFIPTLVGGAFSKVMPNDFMLNLIEGIIRIAILFAYIVL
                     ISRSKDIERVFQYHGAEHKSIYCYENDLELTVENARKFKRLHPRCGTNFLFIVMAVSI
                     ILFAFFGWPNPILRIFMRIICVPIVAGLSYEVIRVLGKYDNGFTKIIAYPGMMLQYFT
                     TKEPDDEQLEVALEALKAVVD"
     gene            71590..72438
                     /gene="prmC"
                     /locus_tag="KRH23_000674"
     CDS             71590..72438
                     /gene="prmC"
                     /locus_tag="KRH23_000674"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0018364 - peptidyl-glutamine methylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HHS5223970.1"
                     /translation="MTIKDIIIKYSDKLKDISDTPRLDTELLLQKTLGVDRLYIHLNL
                     NKELTEEQKTKFMGFAEERLNGRPIAYIVENREFMGLDFFVKEGVLIPRPDTETLVEE
                     IIEICREKKDVSILDIGTGSGAITISLAKYIENSKIMSFDISETALEIAKKNAIINEV
                     GEKIKYINSDLFTAISDSNIKFDIIVSNPPYIKKQDIETLHKQVKDYEPYNALEGGED
                     GLDFYRRITEQGKKYLNKCGILAYEVGHNQAEDVINIMKSNGYKKIYTKKDIQGIDRV
                     VIGYNI"
     gene            72482..73546
                     /gene="prfA"
                     /locus_tag="KRH23_000675"
     CDS             72482..73546
                     /gene="prfA"
                     /locus_tag="KRH23_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003747 - translation release factor
                     activity [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HHS5223971.1"
                     /translation="MLKKLEVLEDTYKDLSEKIGDPDVINDQKVWQKYIKEHADLEPI
                     VMKYREYKSVLDSIKESKEILQEESDEELRELAKMELAEMEEKVAPLEEEIKILLLPK
                     DPNDDKNVIVEIRGGAGGDEAALFAGDLFRMYSRYAERRRWKIELLSASDTGVGGYKE
                     VSFMIKGKGAYSRLKYESGVHRVQRIPSTESGGRIHTSTSTVAVLPEVEDVEVEINPN
                     DLRIDVFRSSGNGGQSVNTTDSAVRVTHIPTGEVVSCQDGKSQLKNKEQALKILKARL
                     YDKALAEQHKDIAAERKSQVGTGDRSERIRTYNFPQGRISDHRINLTLYKLDAFLDGD
                     IDEMIDALITVDQTEKMTAI"
     gene            73675..74355
                     /locus_tag="KRH23_000676"
     CDS             73675..74355
                     /locus_tag="KRH23_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ZIP family metal transporter"
                     /protein_id="HHS5223972.1"
                     /translation="MILKVTIIGLLAGVIGTGLGGVISAIFKREVDKYLSFFMGLSGG
                     IMLAVVVFDLMKESMDKMGIINTVIFTFVGALITMYIKTKLDVSGNMASGYLIFISIL
                     LHNLPEGLAIGSSFMSTESLGITLAIVIGLHNIPEGLAMALGLVCNKMKLSKVILFTV
                     IAGLPMGLGSFLGVYFGGVFTSLIGVFLATAGGTMMYVVLEEIFPHSKSVYCIIGFLL
                     GTMIVNYI"
     gene            74384..75424
                     /locus_tag="KRH23_000677"
     CDS             74384..75424
                     /locus_tag="KRH23_000677"
                     /EC_number="2.7.7.87"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003725 - double-stranded RNA binding
                     [Evidence IEA];
                     GO_function: GO:0061710 - L-threonylcarbamoyladenylate
                     synthase [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonylcarbamoyladenylate synthase"
                     /protein_id="HHS5223973.1"
                     /translation="MKTIISNIDINNIDYEEIKIQAKLLREGKTVIFPTETVYGLGAN
                     ALDENAVKKIYEAKGRPSDNPLIVHIYEKEEVYDLAKDISDKAKLVIEKLWPGPITII
                     LNKKDIIPYKTSGGLDTVAIRMPSNVIARAIIKEAGIPIAAPSANISGRPSPTKAKHV
                     YEEMNGRVDGIVLGGDSNFGLESTVLDLTEETPMILRPGSITKEVLEELLGEVKLDPS
                     LSKKEDNQKAKAPGMKYKHYSPNADVYIISGKRENVATKINDMIKSNRDKGLKTGVMC
                     ISRNREFYDGEVIDLGNSLEEVASNLFDALIEMDKKGVDVIYSEEFPKTGVGQAIMNR
                     LLKSAGYKVIKA"
     gene            75441..75890
                     /locus_tag="KRH23_000678"
     CDS             75441..75890
                     /locus_tag="KRH23_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight protein arginine
                     phosphatase"
                     /protein_id="HHS5223974.1"
                     /translation="MNILIVCTGNTCRSPMAEAILRKAIKESGRSIEEYSISSAGIST
                     ANGMGASENSIEVLKEIGIDLSNHRSKVITKKLIDESDIILTMTKSHKEILVQAVPKC
                     KEKVYTFKGFANKNEEDISDPFGGNLDIYRSTMREIMYSVNEIVKKI"
     gene            75907..76359
                     /gene="rpiB"
                     /locus_tag="KRH23_000679"
     CDS             75907..76359
                     /gene="rpiB"
                     /locus_tag="KRH23_000679"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004751 - ribose-5-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0009052 - pentose-phosphate shunt,
                     non-oxidative branch [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose 5-phosphate isomerase B"
                     /protein_id="HHS5223975.1"
                     /translation="MKIGLGCDHGGYNLKKEIISYLESKGIECVDYGTNNATDSVDYP
                     VYGEIVANSVINKEVDYGILCCGTGIGISLAANKVPGIRCAVVSDVFSAKMSKAHNDA
                     NMLSLGERVLGKGLALEIVEAWISTDFEGDRHARRVNMIKSIEEKHNK"
     gene            76395..77024
                     /gene="upp"
                     /locus_tag="KRH23_000680"
     CDS             76395..77024
                     /gene="upp"
                     /locus_tag="KRH23_000680"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011971477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004845 - uracil phosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HHS5223976.1"
                     /translation="MSKVVETNHPLIQHKLTLMRDKNTGSKDFRELLTEIAMLMGYEI
                     TKDIPLKDVEIETPIQKTSSKVVAGKKLAIIPILRAGLGMVDGLVSLMPAAKVGHVGL
                     YRDPETLKPVEYYCKLPQDIGERDIIVVDPMLATGGSAVAAIDLLKSKGAKSIKLANL
                     VAAPEGIAEVQKYHDDVDIYVASVDERLNEHGYIIPGLGDAGDRLFGTK"
     gene            77325..78140
                     /gene="yqeB"
                     /locus_tag="KRH23_000681"
     CDS             77325..78140
                     /gene="yqeB"
                     /locus_tag="KRH23_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="selenium-dependent molybdenum cofactor
                     biosynthesis protein YqeB"
                     /protein_id="HHS5223977.1"
                     /translation="MKNCIVVRGAGDLATAVIHKLHNSGFKVVALEIEEPLAIRRQIS
                     FCEAVYEKKVTVEGVECIFCNTEKEIEEVLSQHKVALIIDPKGEKLSKLNPIVLVDGI
                     LAKKNLGTTKDMAPLTIALGPGFCAGEDVDVVIETMRGHNLGRIITNGRAEKNTGVPG
                     AIKGFSKERVMHSQYDGIMENVCKIGDIVEKGDLLCYINNYEKKHEVRATISGVLRGL
                     LKDGAKVNKNLKILDIDPRKEEVKNAFTISDKARCIAGGVLEAILNNGIYPQN"
     gene            78366..78803
                     /locus_tag="KRH23_000682"
     CDS             78366..78803
                     /locus_tag="KRH23_000682"
                     /EC_number="3.5.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004132 - dCMP deaminase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006220 - pyrimidine nucleotide metabolic
                     process [Evidence IEA];
                     GO_process: GO:0009972 - cytidine deamination [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="deoxycytidylate deaminase"
                     /protein_id="HHS5223978.1"
                     /translation="MRPSWDEYFMEIAEVVKKRSTCIRRQVGAVIVRDKQILTTGYNG
                     SPRNLEHCENIGCKRQELNIPSGERHELCRALHAEQNAIIQAAHNGISVDGATLYVTT
                     RPCVLCAKMCINAGILKIVYEGDYPDDMSTELLKEAGIELIKF"
     gene            78988..79215
                     /locus_tag="KRH23_000683"
     CDS             78988..79215
                     /locus_tag="KRH23_000683"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045259 - proton-transporting ATP
                     synthase complex [Evidence IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AtpZ/AtpI family protein"
                     /protein_id="HHS5223979.1"
                     /translation="MSKRNTHTEIAKLFSLISQIGLMIVISILGCTFLGKFLDSKLNT
                     TPVLTIIFLLLGVGGAFSGVYKTLIVYTRRK"
     gene            79220..79606
                     /locus_tag="KRH23_000684"
     CDS             79220..79606
                     /locus_tag="KRH23_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase subunit I"
                     /protein_id="HHS5223980.1"
                     /translation="MDIKLLNQVRSVTKGIVIFDVVLIVLMLITSTLSKPVLLGLIFG
                     SIIAMLNFRLLAISLEKSVTFPAGKAQAYASAQYAVRLFIMAVVLIASATVPHLNIIG
                     TALGLLSTKFVILSKNFINKLKRKEA"
     gene            79609..80313
                     /gene="atpB"
                     /locus_tag="KRH23_000685"
     CDS             79609..80313
                     /gene="atpB"
                     /locus_tag="KRH23_000685"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045259 - proton-transporting ATP
                     synthase complex [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HHS5223981.1"
                     /translation="MNQAHYYLIGNFKISETILVSWGIMAFLAIASYFLTRNLKKVPT
                     SKVQIFLEFAVGGLAKMVTDVMGKNTVKRMPYMIPYIGSLFLFFACSNLSPLLGLRSP
                     TTDLDTTAAWAMITFFMIYFAGVKFKGLSYFKELAQPLAIMLPINIIGELARPISLSF
                     RPFGNILGGTIIMGLFYQLLGFISSLIPGLSIPIGEILIPVPLHLYFDLFAGLLQAYI
                     FIMLTMVFISSAGELD"
     gene            80382..80642
                     /gene="atpE"
                     /locus_tag="KRH23_000686"
     CDS             80382..80642
                     /gene="atpE"
                     /locus_tag="KRH23_000686"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045259 - proton-transporting ATP
                     synthase complex [Evidence IEA];
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0 subunit C"
                     /protein_id="HHS5223982.1"
                     /translation="METAIVAAASAIGAGIAVATGIGAGIGQGIAAAKAAEAVGNQPE
                     AKGDITSTLLLGVAIAESSAIYGLVISIILLFVNPFFKYLGM"
     gene            80765..81262
                     /gene="atpF"
                     /locus_tag="KRH23_000687"
     CDS             80765..81262
                     /gene="atpF"
                     /locus_tag="KRH23_000687"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045259 - proton-transporting ATP
                     synthase complex [Evidence IEA];
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HHS5223983.1"
                     /translation="MEKALVGITWEFVFQIVNTFIIFLLLRKLLFKPVLNIIESREND
                     IKSDLAEGEKAKNEGLALKKEYESKINFAKDEGQEIIKQATIRAEQKSDDIVNTAKKD
                     ALDIKEKANKDIEQERQKVINEIKNDISNIALLAASKVIEKDLDKSKHEELIENFIKE
                     VGEAK"
     gene            81259..81804
                     /locus_tag="KRH23_000688"
     CDS             81259..81804
                     /locus_tag="KRH23_000688"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HHS5223984.1"
                     /translation="MINVIANRYAEALFQLGEEENSTDVLFKELEKVVDMMTKVSKDF
                     YKVLKSPLVSKSEKKNLVEIIFSKEVSSNIKNFLKVLVDKDRISYLEDIELAYKELLN
                     KKNNVIDGVAISAIPMSETDIKELEVKLSNKYNKNVTIENVVDKTILGGVLVRIGNEQ
                     IDGTVKTRLDKMKEKLSEVIS"
     gene            81821..83323
                     /gene="atpA"
                     /locus_tag="KRH23_000689"
     CDS             81821..83323
                     /gene="atpA"
                     /locus_tag="KRH23_000689"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045259 - proton-transporting ATP
                     synthase complex [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HHS5223985.1"
                     /translation="MNLKPEEISSIIKQQIKNYENKVELTDTGSVLTVGDGIASVYGL
                     EKAMSGELLEFPGEIYGMALNLEEEVVGAVILGDDSEIKEGDIVKRTGRIVEVPVGEA
                     LIGRVVNSLGQPIDGKGPIAYTKTRPVESEAPGIIDRRSVYEPLQTGIKSIDSMIPIG
                     RGQRELIIGDRQTGKTSIVIDTILNQKGKDVICIYVAIGQKRSTIAQLVSSLEKGGAL
                     DYTIVVSATASESAPLQYIAPYAGAAMGEEFMYNGKHVLIVYDDLSKQAVAYREMSLL
                     LRRPPGREAYPGDVFYLHSRLLERAAKLSDELGGGSMTALPIIETQAGDVSAYIPTNV
                     ISITDGQIYLQPELFYSGVRPAVDPGISVSRVGGSAQIKAMKKVAGTLKLAYSQYREL
                     AAFSQFGSDLDEDTKKRLAQGERIVEILKQGEHQPIKVENQVMIIYAVINNHLEDIPI
                     DNIARFESELYAFVDNNYPEISRKILGGEDFTHDLTDAINEFKEKFVVEV"
     gene            83351..84229
                     /gene="atpG"
                     /locus_tag="KRH23_000690"
     CDS             83351..84229
                     /gene="atpG"
                     /locus_tag="KRH23_000690"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045259 - proton-transporting ATP
                     synthase complex [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F1 subunit gamma"
                     /protein_id="HHS5223986.1"
                     /translation="MAGAGIKAIKTRMGTVESTKQITKAMELVASSKLRKAKEKAEDS
                     REYFNTLYNTVKDIAQTTRGIRNEFLKEREVKNKCYVVVAGDRGLAGGYNSNVLKESV
                     SHMKGKKETVITVGKKAHEFFSKRNYNIAKDINSVEACGYEDATEISQTIIDLYKKGE
                     VDEVYIAYTKFKSALSQEVEILKLLPLVFEKDTDEQGMAVKEEKQNRSKVQYIPSAEA
                     VLSYIVPQFISGTVYGGILESFASEQGARRTAMESATDNANEMLSNLELSYNRARQSA
                     VTQEITEIVGGVEALK"
     gene            84242..85636
                     /gene="atpD"
                     /locus_tag="KRH23_000691"
     CDS             84242..85636
                     /gene="atpD"
                     /locus_tag="KRH23_000691"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045259 - proton-transporting ATP
                     synthase complex [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HHS5223987.1"
                     /translation="MANVGKVVQIVGAVLDVKFDSEQSLPNLLNALVIKLGDKEIVAE
                     VAQHIGDDTVRCIAMSATDGLVRGMEVVDTGGPISVPVGDETLGRIFNVLGKPVDGKP
                     APKSAPKLPIHRPAPAYDELETTAEILETGIKVVDLLAPYLKGGKIGLFGGAGVGKTV
                     LIQELINNIAKQHGGISVFSGVGERTREGNDLYGEMSESGVINKTALVFGQMNEPPGA
                     RMRVALTGLTMAEHFRDEQGQDVLLFVDNIFRFTQAGSEVSALLGRMPSAVGYQPTLA
                     TEMGALQERITSTKKGSITSVQAVYVPADDLTDPAPATTFSHLDAKTVLSRQISSLGI
                     YPAVDPLESTSRILDPSIVGKEHYEVARGVQSILQRYKELQDIIAILGMDELSDEDKL
                     IVARARKIQRFLSQSFTVAEQFTGNPGQYVPVKETVRGFKEILEGKHDDLPESAFLFV
                     GTIEDAVRKAKGSM"
     gene            85639..85899
                     /gene="atpC"
                     /locus_tag="KRH23_000692"
     CDS             85639..85899
                     /gene="atpC"
                     /locus_tag="KRH23_000692"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045259 - proton-transporting ATP
                     synthase complex [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F1 subunit epsilon"
                     /protein_id="HHS5223988.1"
                     /translation="MASEFSLKVVTPSNTFYDGDVEMIVVRTTKGDKGVLKGHIPFVS
                     GIPVGTLKIKKEGSFKEAKIAEGFINVTQDKTVILTESAEWI"
     gene            86361..86741
                     /gene="acpS"
                     /locus_tag="KRH23_000693"
     CDS             86361..86741
                     /gene="acpS"
                     /locus_tag="KRH23_000693"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008897 - holo-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HHS5223989.1"
                     /translation="MNIFDIGVDIIEIDRIRKAVDKNNRFLEKIFTDREIEYFNSKNF
                     KAESIAGNFAAKEAISKSIGTGIRVFNFKDIEVLRNEMGKPIVKTYNNLAKMCIDYNV
                     LEIKVSISHSKDYAIANAITIIKD"
     gene            86756..87217
                     /locus_tag="KRH23_000694"
     CDS             86756..87217
                     /locus_tag="KRH23_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HHS5223990.1"
                     /translation="MMDKTAKEIMTTDVIVAKQDDSIADVANMLIAEKIGGLPVVDSE
                     NRVVGIISETDILKKEKYIEAPLYINLLQGLIFLDDLKKVEKDIKQVAAYKVGELMSK
                     DIIKVHEDDKFDDVANVMIKKSINRVPVVDDDNKLKGIICRYDIIKALYNE"
     gene            87238..87828
                     /gene="gerS"
                     /locus_tag="KRH23_000695"
     CDS             87238..87828
                     /gene="gerS"
                     /locus_tag="KRH23_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="germination lipoprotein GerS"
                     /protein_id="HHS5223991.1"
                     /translation="MRKKWTIVCIMFLALVIIVIGCQKRQSTKEEVYKDFQKQISDMN
                     YYSCKAEVEVVGNKSPHNYVLIHTYKKTDNYKLEVISPKHLKGKSIEYQGDKILVKNP
                     KISDVVELPNTGKNNQYLFVGDFIKNYLQNEEMKVKLSKGHLVLETFIPGDNKYFNKQ
                     VLYVNADTKNPEKMEVLDKEGVPRFTVKYKDFEYRN"
     gene            87843..89000
                     /gene="alr"
                     /locus_tag="KRH23_000696"
     CDS             87843..89000
                     /gene="alr"
                     /locus_tag="KRH23_000696"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008784 - alanine racemase activity
                     [Evidence IEA];
                     GO_process: GO:0006522 - alanine metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HHS5223992.1"
                     /translation="MQKITVPTWAEINLDNLRFNLNNIKNLLEEDIKICGVIKADAYG
                     HGAVEVAKLLEKEKVDYLAVARTAEGIELRQNGITLPILNLGYTPDEAFEDSIKNKIT
                     MTVYSLETAQKINEIAKSLGEKACVHVKIDSGMTRIGFQPNEESVQEIIELNKLEYID
                     LEGMFTHFATADEVSKEYTYKQANNYKFMSDKLDEAGVKIAIKHVSNSAAIMDCPDLR
                     LNMVRAGIILYGHYPSDDVFKDRLELRPAMKLKSKIGHIKQVEPGVGISYGLKYTTTG
                     KETIATVPIGYADGFTRIQKNPKVLIKGEVFDVVGRICMDQIMVRIDKDIDIKVGDEV
                     ILFGEGEVTAERIAKDLGTINYEVLCMISRRVDRVYMENNELVQINSYLLK"
     gene            89033..89320
                     /locus_tag="KRH23_000697"
     CDS             89033..89320
                     /locus_tag="KRH23_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribbon-helix-helix protein, CopG family"
                     /protein_id="HHS5223993.1"
                     /translation="MYDKSKEKIEVTLPDSLISEVDSIVQMENSNREDFAKAAFQFYI
                     TQKKKIHIKESMKTGYREMGQINLSLAELGMTVEEVSSDDKNEGKIAQGEY"
     gene            89289..89672
                     /locus_tag="KRH23_000698"
     CDS             89289..89672
                     /locus_tag="KRH23_000698"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004521 - RNA endonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006402 - mRNA catabolic process [Evidence
                     IEA];
                     GO_process: GO:0016075 - rRNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HHS5223994.1"
                     /translation="MKGRLPKVSTNCEIKRGDLYYADLSPVVGSEQGGVRPVLIIQND
                     VGNKYSPTVIVSAITSQINKAKLPTHVEISSNEYGLNKDSVILLEQIRTIDKKRLREK
                     IGCLDENMMIKVDDGLQISLGLFTF"
     gene            89843..90670
                     /locus_tag="KRH23_000699"
     CDS             89843..90670
                     /locus_tag="KRH23_000699"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HHS5223995.1"
                     /translation="MRDHKGLNEIARIIRRDIVSMIHRAKSGHPGGSLSVVEILTALY
                     FDEMNVDSSNPKMEDRDRFVLSKGHAAPALYATLAEKGYFDKEELNGLRKIGRMLQGH
                     PDMKGTPGVEISTGSLGQGFSVACGMAMASKLDNAPWNVYTLLGDGEVQEGIVWEAAM
                     SAAHYKLDNLIAFLDNNGLQIDGDIESVMSLGSIVDKFKAFGWNVIEIDGHDFDQIFA
                     ALDIAKSTVKKPTMIVAKTIKGKGISFMENQAGWHGTAPSDEELEKALLELGGADNE"
     gene            90663..91604
                     /locus_tag="KRH23_000700"
     CDS             90663..91604
                     /locus_tag="KRH23_000700"
                     /EC_number="2.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HHS5223996.1"
                     /translation="MSKMATREAYGKALVKLGQINDNVVVLDADLSKSTKTHDFYKSF
                     PDRFFNMGIAEQNLIGAACGLSTAGKIPFASTFAMFATGRAFEIIRNSVCYPKLNVKI
                     CATHAGLTVGEDGASHESVEDIAIMRAIPNMTVLVPADGVETEKIIFEIAKYNGPVYV
                     RLGRSSVPVLFDEDYKFEIGKGTVLREGKDVSIIACGIMVNEALLAQEKLQEEGISAR
                     VINMSSIKPIDKDLILESAKETNAIVTVEEHSIIGGLGSAVSEVVGESCPTIVKKVGI
                     KDTFGESGAPNELLKKYELTCDDIVKTVKEAIIAKRM"
     gene            92027..93121
                     /locus_tag="KRH23_000701"
     CDS             92027..93121
                     /locus_tag="KRH23_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YkvI family membrane protein"
                     /protein_id="HHS5223997.1"
                     /translation="MSEKVNVKTVISFAGAYVATVIGSGFATGQEIMQFFSFYGFAGI
                     IGGIISMVLFSWMGASVMSKGKELQLKEPIKIYRVYCGKYLGIFFEWFGPLFLFGVFV
                     VMISGAGATLTEYYGLNPFVGRVGMAVVALLTVSLGLDKLSKILGGIGPIIIIFTLLV
                     GGISLAKNIGNIGEAAQVLSTVKIAKPVPNAYLSGVIYTTYNTIVVMAFLTGLGASAA
                     NKKEAICGGILGGVALMAAAIMMHLAILSDIGNLYSKAIPSLFLADKISPVIGVLFSI
                     ILILGIYTTAVPLLWSVTNRFVDDKHPKFKLITLIAAILGLIGGFLPFDKLVGILYPY
                     TGYMGVIILVCVLYRQITKTSGYQEGISDK"
     gene            93347..93763
                     /locus_tag="KRH23_000702"
     CDS             93347..93763
                     /locus_tag="KRH23_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5223998.1"
                     /translation="MNVKFNIKGIIYGVIALVFVIGGFIFIPSMFVEKSKPIDYTVLQ
                     RNSIPEKILDVMDKYTNEERALAAKIDNKIYIIVTRGNNKYGIEMDKIESVVEEGKDV
                     LRVKIKYKDKEDSFPYIVVETNMSELPDRIELNATK"
     gene            complement(93945..94514)
                     /locus_tag="KRH23_000703"
     CDS             complement(93945..94514)
                     /locus_tag="KRH23_000703"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030272 - 5-formyltetrahydrofolate
                     cyclo-ligase activity [Evidence IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HHS5223999.1"
                     /translation="MKKEFRKKVIESRKNKSANFVLSNSNLITEKLLQMEDIRNATNI
                     MLYLNFNNEVQTDNLIKKLLSLKKIVSSPITIKENHTLIPTQITDLKEGLRIGAYGIR
                     EPNEKSSTIDIKALDVVIVPAVAYDIHCYRLGYGGGFYDRFLENLRKDAITIGIAFDF
                     QIFDSIPKETHDAQLDYIVTETRIITPNS"
     gene            94668..95825
                     /locus_tag="KRH23_000704"
     CDS             94668..95825
                     /locus_tag="KRH23_000704"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S41 family peptidase"
                     /protein_id="HHS5224000.1"
                     /translation="MYLVISKKKAIFLGVILVIITAMVTSAFQLTLGNKVVISKELYE
                     DYKKYDKLLGLESIIKQDFYKKVSDADLVNGAAKGLFLGTNDKYSGYYTKDEMENLIN
                     DSEGSYVGVGMYIGASKDGGLVVVPMKDSPAEKAGVKSGDKLVKVNGKSVSYKNSDEA
                     VRMMKGKKGKTVELTILREDKQLNFKVKTDQIIEKSIESKVIDNDLGYIEITQFISST
                     YTDFDKALKELKAKNIKGLVIDLRNNPGGMLDICKEVADELIGEGTIVYTKDNKGNTE
                     YLKSDKEKLGLPIVVLTNGESASAAEILTAAIVDNKEGISVGTTTFGKGLVQSVVRLK
                     DGTGYKLTTAQYFTPNGDYINEKGIKPTIEEKDENKQLDVATKWLREQIDK"
     gene            96429..96899
                     /locus_tag="KRH23_000705"
     CDS             96429..96899
                     /locus_tag="KRH23_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0002161 - aminoacyl-tRNA deacylase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YbaK/EbsC family protein"
                     /protein_id="HHS5224001.1"
                     /translation="MYNNIKNILKENHITFEEYDHEPILSFEKAKEIREKLQYTGVES
                     KSLFIKDRSGNYYIFVTTEGKKLDPKTIKNVLGGKVSICSKEELTQKTQCLPGCVSPF
                     GYEKNISLVIDQDIFNHDKIIFSPGIPEKTFIITASGFKKVINNINNTTYKYIY"
     gene            complement(97455..98609)
                     /gene="nagA"
                     /locus_tag="KRH23_000706"
     CDS             complement(97455..98609)
                     /gene="nagA"
                     /locus_tag="KRH23_000706"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008448 - N-acetylglucosamine-6-phosphate
                     deacetylase activity [Evidence IEA];
                     GO_process: GO:0006044 - N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HHS5224002.1"
                     /translation="MKSFIYADKFFMKHGIKEKGYLSIINGKFGEFQQERPNITDNVI
                     DFSGKYIAPGLVDTHIHGLLGADVMDNTFEAINTISKGLLKYGVTSFLPTTLTDSVDT
                     LSDSVENISNSFNRVEGAKIQGIYLEGPFFTEKYKGAQNEKYFKDPDINILKLWQKKS
                     KNLIRKIAIAPERKGSIELTRYATKNNISVSLGHSSATFEQVKQVVNSGAKVFVHTYN
                     GMSPLNHREPGMVGAAMVLKDTYAELICDGHHVSPIAVKIIMDAKSSNNIALITDCMR
                     AGAMEDGKYTLGKFNVNVKNSVARLNSGSLAGSVLTMDKAVRNIVDWNISTLEDAIKM
                     ATYVPALSCNIDNVCGSIYQGMDADFIVTDNDFNIHETYINGICKYKVNK"
     gene            complement(98692..99417)
                     /locus_tag="KRH23_000707"
     CDS             complement(98692..99417)
                     /locus_tag="KRH23_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HHS5224003.1"
                     /translation="MIKRNDKRPIYDQLVEILRTKIENEMEPNDRMLSERKICDEYGV
                     SRTTVRLAMAELEHMGYIYKRHGKGTFVAALSQNSQNLMESYSFTDYMRTQGKKPGTK
                     VLSFEVVESTKYFSEKLGITTGEKMIKIMRLRLADDLPMMLERTYLPMKEFIGLTKEK
                     IEQKPLYEIFREDYGEIIKVADEEFSAGIISDKEAKLLEVPGDSPCLKLLRTTYNDDN
                     IVIEFTLSVARSDKFVYRVRHVR"
     gene            99686..100615
                     /gene="pfkB"
                     /locus_tag="KRH23_000708"
     CDS             99686..100615
                     /gene="pfkB"
                     /locus_tag="KRH23_000708"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008662 - 1-phosphofructokinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HHS5224004.1"
                     /translation="MITVITFNPSIDRMYRVNNINIGEVQRVVSKNATAGGKGLNVAK
                     VCKILKENPLAMGFLGGFNGEFIKNELRKLDIQNKFTKIEQETRNCLNIIEDNKVSTE
                     FLEKGPIVEKSNLERFENDIEEVLKNTKILVASGSYCENMPIDYYEKIGNICRANNIK
                     FILDTSGEALKIALKSKPYLIKPNIDEIRHLLGINIESREEIILSGKKLIEMGAENVC
                     ISLGKDGMVYLNEDNVYDVKVPVVKCINTVGSGDSTVAGFSVGILRGYKIENLLKFAN
                     ACGISNALNMETGFVDLGEIDKYQDLVEVKKLS"
     gene            complement(100738..101655)
                     /locus_tag="KRH23_000709"
     CDS             complement(100738..101655)
                     /locus_tag="KRH23_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family protein"
                     /protein_id="HHS5224005.1"
                     /translation="MKNIKMGMIGLGSIAQKAYLPILTKSERFEFVGAFTPNKVKREK
                     ICSDYRIMPFDSIESLAKKCDCIFLHSSTETHYEIIKILLNLGVHVYVDKPLASTVSQ
                     GEELIELSTKKNLNLMVGFNRRFCPMYKEIKNNATEIVSINICKHGLNSLRNVKFDST
                     LIDDYIHVIDTALWLANEDVEISGEDLFLTDNKNLIFVSHKLKCKNFSINTSMHRDSG
                     TKLEQVEILSKGKIQRVKNLNVLEIEEGGNLTLKQSGAWVNILKQKGFEDISNHFIDC
                     IENNIKPAISGEECIKAQRLLEKIINSVK"
     gene            102132..103295
                     /locus_tag="KRH23_000710"
     CDS             102132..103295
                     /locus_tag="KRH23_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HHS5224006.1"
                     /translation="MFKLEEQKLKVLGAIITTNEIKQQPELWLETYEIYKSNKEKLSR
                     FIDTISNNHGQFRVIFTGAGTSAYIGNSILPYLKNKNDIRKYIFEAIPTTDIVSNPYD
                     YLKKDIPTLLISFARSGNSPESLAALNLGNKIVDNFYHLAITCNPEGELAKMTKNDEN
                     NYLLLMPSKSNDEGFAMTGSFSCMMLSAMLIFDSLEDDVEKSYINAIIEMGRNVIDRK
                     DEIHELINKDFDRVVYLGSGGLGGLTQEAQLKLLELTAGKISTVYDSPMGFRHGPKSF
                     IDENTLVFEFVSNCLYTRKYDLDVLEEIKRDKIAKFTCAVSVENENNFSGTKFEFKEK
                     YNKLPDVYLAMPYILFAQTIALFVSVKVGNKPDTPSATGTVNRVVKGVTIYEY"
     gene            103344..104195
                     /locus_tag="KRH23_000711"
     CDS             103344..104195
                     /locus_tag="KRH23_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase subunit GatY"
                     /protein_id="HHS5224007.1"
                     /translation="MALVTTTSMLKKAQDEGYAVGAFNVENMEMVIAVIEAAEELNSP
                     VILQTTPSTVKYAGLDYYLANAKVAAERVNIPVAMHLDHGSSFDLAMKALRSGYTSIM
                     IDGSHESFENNISISKSVVKACSPSLIPVEAELGKVGGKEDDLDGGNSNDYTNPKEAK
                     EFVDRTGISSLAIAIGTAHGLYKGEPKIDLDRLSEIKNVVSIPLVLHGGSGIHDDIIK
                     EAIKRGIAKVNYATELRIAYSKGVKKVLDEDSEVIDPKKYGLAGLQSVKDFVKEKIKV
                     CGSVNRV"
BASE COUNT        41665 a        11380 c        18842 g        32358 t
ORIGIN      
        1 attttttgtc aaaaaaaaca aaaaatacgt atttcttttt tcatttcggg aaaactaaac
       61 acaggaatta tggactttat aaaaatttaa ttcttgagga gtgatataag tgaaaaaagt
      121 tgctttaatt ttagctataa taggtgcgct taactggggt gcaattggta ttctaggtac
      181 agacttaata ggtagtatct ttggtggaac atatgaaatg gtaagtagaa taatatactt
      241 cattgtaggt ttagctggat tatacttaat accaagttta atgtctgatg atagagaata
      301 atttatgctt ttatgttaaa tacctcattc taaatgttta gaatgaggta tttaatttta
      361 taaaaatatt aatttgtttc ttttttaatg gtaaaataga taagaattga agttttaaaa
      421 agaagtatta tgtaaaaaag gagtactatt aatatatgtt tattattaat gaattaaata
      481 agattgtaaa tgaagaagta atatcttttc atatgcctgg tcataaaaag ggacaggttt
      541 ataaaaagtt aggatataaa gatatactaa aaaatttgta taaaatggat acaactgaga
      601 tattaggaac agataattta cactttccgg aaggaattat aaaaaattca caaaaaaaag
      661 catcaagagt atttaaaagt gattatactt gctatttagt aaatggtagt agctgtggaa
      721 tacaatctgc aataatgtca gtatgtagtc ctaaaagtaa aataataaca aatagagact
      781 gtcatcagtc tgttataaat ggatgtattt taggagatat agatatagag tatgtgcctt
      841 gtgagataag tgaagagaca aatatcttaa aagggatatc tataagtaat gtgattgata
      901 taatagataa aaacttggat gcaaaagcag tgctgcttac ttatcctaca tattatggaa
      961 tgacatatga tttagaatac atatgtaatt atgcacatag caaaaagatg gtagtgatag
     1021 tagatgaagc acatggtgcg catttagggc ttagtgagag gcttcctaaa acagctcttg
     1081 agcaaggtgc agatatagtt gtacagagta cacataaaac tcttccagca tttacacaat
     1141 cgtcaatgat acatatacag ggagaccgag ttgatataga taaaatattg aacatgttaa
     1201 gaattacaga atcttcaagc ccttcatatt tattattatc ttctctggaa ttagcagtag
     1261 atatatatga aaataaagga aaagaattaa tggaagagct tttaaataat attataactt
     1321 tcaaaaataa agttgattca aatattaata tatacgacac aaatgataaa acaaaaatat
     1381 ttatatcatc taaaaacatg ggtttaacag gttatgaact agaaaatatt ttgagaaata
     1441 aatataacat acaagtggag ttatctaatt attatggagt tcttttaata tgtacaatag
     1501 gaaatactgc tgaggatttc tctagtttag aaacagcatt aaacaatgtt gtaaaggaag
     1561 actttaaatt tgaaaagtta gaaaataaaa aataccctgt tgttattcca aagaaaatat
     1621 taacacctag agaagcattt tataaaacta aaaaaagtgt taaaatatat gacagcatag
     1681 gtaaagtttg tggtgaatgt atagttccat acccacctgg aataagtgta atatctcctg
     1741 gtgaagtaat aagtaaagaa ataatagact atctaatgtt ttgtcattct aaaggcatga
     1801 ttgtgagtgg attgaaagat gtagatttaa attttataca agtaatagat ttagaagaca
     1861 tttaaaaatt atgatataaa agtagataga agtagatagt ttaaaattgt gaagagaaat
     1921 aaatagactg cttatataga gatatctaat aaaagtacta aaaaagtaaa aagtgtttgt
     1981 atggaggata tgaaaatgaa aggtaagtta ataattatag agagtggttc agatgcaagt
     2041 ggaaaggcta ctcagacaga aatattatat gaaagattaa aaaaagaagg ctatatgatt
     2101 aaaaaggtag aatatccaaa ttatgaatct ccatcatctg ccttggtgaa aatgtaccta
     2161 aaaggagact ttggtaaaaa tgcatcagat gtagacccat atatagcatc aacttttttt
     2221 acagctgata ggtatgcatc atttaaaacc gattgggagg agttttacaa tgaaggtgga
     2281 ataattatcg cagatagata tacaacctct aatatggtac atcaggcctc taaaatggat
     2341 atttgtgata gagaagagta tttaaattgg ttagctgatt atgaatttaa tttatttaag
     2401 ataccacagc ctgattgtgt tatattttta gatgtgccta ttgaatttag taaaaagctt
     2461 atggagaata gaaaaaataa aattacaggg gaagaaaaaa aggatattca tgaaagtgac
     2521 atagagtatt tagagaaatc ttacaacaat gctttatata tagcagataa atatgattgg
     2581 aaaaaaataa attgtgtttt agataacaaa ttaagaagta ttgaaagtat acataatgaa
     2641 atttataaaa tagttcttga ttcaataaaa cctatggaga gataaatatg tattttgaaa
     2701 atattatagg gcaagatttt gcaaagaaat atttaacaaa ttctataaag aaaaataaac
     2761 ttaataatgc gtatatgttt gaaggaatgg atggaatagg aaaaaagaaa tttgcagatg
     2821 aattatcaaa actattactt gattatgaaa atctcgaaaa tagtccagat tatgtactca
     2881 taaaaccaga tggaaatagt ataaaaatag ctcaaatcag aaatttacaa tcagatatag
     2941 taataagacc tcataaagac tataaaatat atataatcaa taatgctgaa aaaatgactg
     3001 tggaagctca aaatgcactt ttaaagacgc tagaggaacc tccaaactat gctataataa
     3061 tcttagtcac aaacaacaag gaatctttat tagaaactat aaaatctaga tgtgatataa
     3121 taaagttctc acctatacca attgaagact taaaacgtta tttgataaat acaggtatag
     3181 aagaagaaag agctcaatta ttggctattt tttcgagagg aagtattgag aatgctctaa
     3241 atctatctca gtcttctgag ttttcaatga tgagagaaga tatacaacag tatattcaga
     3301 taatgttaga taaaaacata gtggagattt taaatatacc aaataatatg gaaaaatata
     3361 gaggtaagat tatagcttta ttagatatga tgataaacta ttttcgagat atcatcctat
     3421 taaaagaaaa tgtaaacaag aacatgttaa taaatgtaga taagctagtt ttcattcaaa
     3481 atatgagtgg aaaaattagt tattctcaat tgtccaagat tattgatata atagaagatg
     3541 caaagagtaa aataaaaagc aattgcaatt tcaatataag catacaagtt atgtctttaa
     3601 atatatacga ggtgattaaa tgataaagat agtaggtata aggtttaaaa gtgctgggaa
     3661 aatatattat tttgaccctg ttgattttaa tatagagcaa gatatggatg tagttgtaga
     3721 aactgcaaga ggcttggagt atgggaaagt agtcgttggt ccaaaagata tggatgaaag
     3781 cgaattagtt tctcctttga agccaattat aagaatagct acagaagaag ataaaaaagt
     3841 atatctagaa aataaggaaa aggcaaaaga aacttttgag ttgtgccaac aaaaaataaa
     3901 agaacatgag ttaacaatgt ttttaataga ttgtgagtat acatttgata ggaataagtt
     3961 gattttttac tttacagcag aaggaagaat agattttaga gaattggtaa aagacttagc
     4021 tgctatattt aaaactagaa tagaacttag acaaataggt gtcagagatg aagctaaatc
     4081 tataggaggt ctagggcctt gtggtagaaa actttgttgt tcatcttggt taggtgattt
     4141 tcaaccagtt tcaataaaaa tggcaaaaga ccaaagtcta tctctaaatc caacaaaaat
     4201 atctggaata tgtgggagat tattctgttg cttaaaatat gagcatgatg tatatagtga
     4261 agcaatagaa aaaatgcctg ttgtaggtgc attggtgcaa tcagatgatg gaaaaggaaa
     4321 agttgtagaa gtgaatcctt tattagaaca aattaaagtg gaatttcaag acaagacagt
     4381 aaagatatac acaagagaag atataaaaat acttagagag cctaaaaaat gtgatggctg
     4441 tggtggtaaa tgtaaggata atgatggatt agatgaagcc acactaagag agctaaagaa
     4501 attagaagat taaatttaag gtagggcttt tcctaccttt tttaaagcaa ttaatgctta
     4561 aagttattaa tatttgagga gaatttatat atgcaattaa aagattcaga aagaatagat
     4621 gatttacaat taaaaggact taaaattata caagatacta atggtttttg ttttggtata
     4681 gatgcagttt tattagccaa ttttactaaa ataaaaaaag atgccaaagt agtagatttg
     4741 ggtactggaa ctggaattat acctattttg atagctggaa aaagtgaagc taaaaaaatt
     4801 attggcgtgg aaatacaaga agatgtatat gaaatggcaa ctcgttctat aaaattaaat
     4861 ggattagaag aaagagttga gattataaat gaagatataa aatacataga caaagtctta
     4921 gacataaatg gttaccatgt agtcacatca aatcctccat atatgcatat tgatggaata
     4981 aaaaatccaa atgataaaaa agcaatatca agacatgaag taaggtgcaa tttggaagat
     5041 gtaattagag ctgcatccag attggttatg cctagaggaa aattcttcat gatacataga
     5101 ccaacaagat tggttgatat aataacttta gggagaaaat ataaattaga accaaaggtt
     5161 attcaatttg tgcatccaag acctcaaaaa gcaccgaact tagttttggt tcaatttgta
     5221 aaagatggaa ggccagagct taaaatattg gacccattgt atgtttatgg agaagatggg
     5281 aattatacaa aagaattaaa agcaatatat aataataaag atataggaga gttgtaaatg
     5341 agcgggaaat tgtacatatg tccaacacca ataggaaacc tagaagatat aacatataga
     5401 actttaagaa tattaaaaga agtagacttg attgcagcag aagatacaag acatagtata
     5461 aaacttttaa atcattttga aatctcaaaa ccactaacta gttatcatga acataataag
     5521 gattcaaagg gagattattt gataaataaa ctaattgatg gtgaaaatat agctctgata
     5581 agtgatgcag gtatgcctgg tatatctgac ccaggagaag agataataaa acaagctata
     5641 caaaataaca tagagataga agtattgcca ggtgcaacag cctttgtaac ggctttagtt
     5701 ggctctggta tggacacaca tagatttgtt tttgagggct ttttagatag agataaaaaa
     5761 gttaggaaag cacaattgga agaattaaag gaagaaagta gaactataat tttctatgaa
     5821 tcaccacata gattgaagga tacactaaaa gatatgctta aaattcttgg taataggaat
     5881 atttctataa atagagaact tacaaaaaaa tatcaagaaa taataagaga aaatatagaa
     5941 actaccataa aaatatttga ggaaaaagaa gtaagaggag agtttgtatt aatagtagag
     6001 ggttttcatg gtgagaagtc aaagaaagaa aattatgatg ggcttacaga tagggaatat
     6061 gttttaaaac taattgaaag tggtatgaac aaaaaagatg caataaaaat agtttgtaaa
     6121 gatagaaagt taaagaaaga tgtggtttat aaacaagttt tagatttata aaacctgaat
     6181 ctgaggtgat tttatggaaa taggaaaaat tataatagag agtttaaaga gggaagatac
     6241 acataaaata tttatagaat tagataataa gcatgaatta gaaaaaataa ttcctaaaat
     6301 aagctgtatg aagtctgtag gtgaatgtaa atatcatgta gtaaattgtt ttgaacattc
     6361 tataaatgca ttaaaagaat tagaaatagt attaaatgat aaggattttt ttccaataca
     6421 tctaagaaaa catgtgtcaa actatttaaa aacatatatt gaagaaggaa taaataagtt
     6481 acatgtatta aagctgggaa catttttaca tgatataggt aagcctgaca gtatgacctt
     6541 agatgaaacc ggaagagttc atttcacaaa tcatgaaaaa ataggtgctc aaataattga
     6601 caatatggga ataaagttag agttatcaac agagacatat agacttataa gtaaatatgt
     6661 aagatatcat atgatacttt tgtctctata taagaaaaat gatttgagta ggaaagaatt
     6721 aattaatgta tttaacttag tagatgagga tactataggt gtaataatgc ttgggtatgc
     6781 agatatagtg tctacagtaa aattattggg caagagtgga gaagtcagtg tgttaaagac
     6841 atatatggaa tatattttaa caaattactt gtataagagt aattatacac atgtataaat
     6901 ttagttaata taattgagtt ttagatgatt aattgaagtt tgaaatatac ggatttcaaa
     6961 aacataaaag aagttgtctt tgttgtaaaa ttatgaaaga caactttttt tatatcaaaa
     7021 attgaaattt tattaaggat acttaatggt ctattaatta ataaaccatt agtatttaat
     7081 ttatattaca atattgattt tgcttgtatt ggcgttgata gtataacaga ggtcttagta
     7141 gaaccaattt tctttatagt atcaatcaca ttttctagct cgtacatatc ttttacaatt
     7201 acttttaaaa gtaagcaatc atcacctgtt atatggtgac attctacaat cctagggtcc
     7261 tttgcagctg actcaataaa ttctgtatat ccattgcttg gaagagaaat atgaataaat
     7321 gcctttataa ctctgcctaa tgaatctggg ttgacaatag ctttatatcc ttctataaca
     7381 ccagactctt ctaatctttt gactctttct gaaactgcag gagaagttaa accaactatt
     7441 tttcctaagt ccttcataga aattctccca tcatcctgta aaatttctat gattctgtaa
     7501 tctgtaacat ccataaataa acagtccccc ttaaataaaa ataattaatg ctataaaact
     7561 tttttagaat ctatcatttg tgtttttaaa taccaaagat ttctagataa atcaacctta
     7621 taaatgtgtg gttttgaaag tcttttgtat tgttcccaga tagtacttaa ttcatattgt
     7681 acatgatttt ttatttcaag aacagctttt ttattatatt tgcatctgcc ttttatatac
     7741 aatggtttaa gaagctcttt aactttgtaa tttgtaaata ccttcgtttt ccatgtataa
     7801 gtaggatgga agatttctaa aggtttagac tcatctataa cttcatcatg taacataatc
     7861 aaatctgcct ctgccttatt gtcttcgtta tatattctta taactttctt gtaaccagga
     7921 ttatttattt tttctggatt ctcagaaatc tttatcttag gttcaagaac tcctttttca
     7981 caagatgcag ctaatttata aactcctcca agagaaggtg aatcgaaaga tgtaatgagc
     8041 tttgtaccta ctccccatga atttatagta gctccttctg ctttaagtga tgttatggta
     8101 tattcgtcta ggtcattaga tgcagtgatg ctgatatctg aaaagccagc attatctaat
     8161 tgttttttag cttctttaga taaataagct aaatctccag agtcaagtct tatacccata
     8221 ggtttgtatc ctttttcaga aatatttttg aatactttta ttgcattagg aactccactg
     8281 tttaatacat cataagtatc tacaagtagt aggcatttat ctggataaac atcagcatat
     8341 gcttggaatg cttcaagttc attatcaaat ttttgtaccc aactgtgagc ttgtgtacca
     8401 attataggta tatcaaacat tttccctgct agtacgtttg cagttccagc acaaccacca
     8461 actacagcag ccctagctcc atatatccct gcatctggac cttgtgcacg acgtaatcca
     8521 aattcaaata cagggtctcc ttgagctgca aagcaaactc tagaggcttt agtagcaata
     8581 agagactgaa aattaactat tgttaacaat gctgtttcaa taagttgagc ttgatataaa
     8641 ggtgccttaa cagtaattaa tggctcatta ggaaacatga tagttccttc ctcaacagca
     8701 tatatatctc ctgtgaattt aaattctttt aaaaatttta agaacttgtc agaaaataaa
     8761 tttaagtttt ttaagtactc taaatcttca tctgaaaaat gaagattatc tatgtattca
     8821 acaacctgat caataccaca aactatagta taccctccat cacaagcgtt ttttctaaaa
     8881 aacatatcaa atacaacaat gtcttcatga atattctttt caaaatagcc atttaacata
     8941 gtaagctgat ataaatcagt aagaagtgtt agatttctca ttatttctct ccttaattat
     9001 tattaaatat taaaaattgt aaaaactccc acacttatac taaaacataa tatagtacaa
     9061 ctttcaagta taaagtatta cctaactatc ataaaattat ttaaagagga ggatgattat
     9121 aataggaaaa atatggtttt atatggtatc gataggaata ataggaagct tgatttctaa
     9181 aaatatgggt gaattaaata aagttatatt aagtgaaaca tcaaaaggta tagagtttgc
     9241 aataagtcta gctggtatca tggcactctg gatggggata atgaatatcg caaaagaatc
     9301 aggtttaatt gaaaagatag gtcaaaaact aaatcctata atgagaagat tatttccttc
     9361 tattccaaag ggtcataaag caatgtctta tatagttatg aatattgctt taaatatgtt
     9421 gggtgctgga aatggtgcaa cagcatttgg tttaaaagca atgagtgagc ttcaaacttt
     9481 gaataacaag aaagatacag ccactaatga tatgattatg tttatggtaa tcaatatatc
     9541 atctatacaa ataattccat ttactataat caaattaagg atggatatgg gggctcaaaa
     9601 tccaagtgaa ataattttta cgactttatt tgcaaccata atatctacag cagtagcaat
     9661 aataacatgt aaattttttc aaagaagata tagataaagg ggatgtagat acatggagat
     9721 attttcaaac ttacttatac caataataat tctgtacata gtaatttatg gtaaatataa
     9781 aaaaatagat gtgtatgata gttttgtaaa aggagcaatt gatggattaa aagctgcatg
     9841 ggatatccta ccatatataa taggtatatt tttggcaata ggaatattca aaactggtaa
     9901 aggtcttgat atgttagaat ggctatttac accaatagca aatatgatga gtataccaaa
     9961 agaattaata ggtctaataa gtgtaaaacc tttatctgga agtggtgctt tggggatgta
    10021 cagtgaactt gcaaatagag ttggaatagg aagtttagta gaaaaaatgg gtgctacgat
    10081 tgtaggttct tctgagacta ttttttacac aatggcaata tactatggaa gtctgaagat
    10141 aaaaaatact agacatacat tatcatgtgc tatgattagc catgttgcag gtgtcatagc
    10201 agctgttttt atttgctatg taatatttgt ataatttgtt gacaatatgg gaaaaatttt
    10261 ataatatagt gattatatag aaacaaatag taatacaaat tacaagctat gaaaagaaga
    10321 gtaaataaag gttttttcta tcagagagct aggttaggtg aaagctagtg tcaaaagctt
    10381 tattgaagat ggtcttggag ctttttatct gagcaagtgt gctagggtaa aacggttgga
    10441 cacgttatag tctactaagg tatctataaa atgtttctac atttcatgtg aaacataact
    10501 attatagatg aattagggtg gtaccgtgaa taatctcgcc cctatgttaa ctcataggag
    10561 gcgatttttt attatttaaa tgaaagaatc atatgattac gaacgataaa aaattaggag
    10621 gtaaataaca tgagcaaacc gagtttttat gtaacaacac caatatacta tccaagtgga
    10681 ggattacaca taggacatac ttattcaaca gtagctgcag atacaatagc tagattcaag
    10741 cgtttctgtg gatatgatgt aaagttctta acaggaacag atgagcatgg tgaaaaaatt
    10801 caaaagaaag ccatagaaca aggaatgtca gagatagagt atcttgatgg aatgataaaa
    10861 gatataaagg ccttatggaa tactatggat atatcttatg atgattttat aagaactaca
    10921 gaaaaaagac atacagacat aatacaaaag atatttacta aactatatga gcaaggtgat
    10981 atatataaag gtgaatatga aggtagatac tgtactcctt gtgagagttt ctggacagaa
    11041 tctcaattac tagaaggaaa taaatgccct gactgtggaa gagaaacata tttagtaaaa
    11101 gaagaatctt atttctttag attatctaaa tatgaagaca gattaaaaga gttatttaaa
    11161 gatgatagtt tctgttttcc tgctgctaga aaaaatgaaa tggtggcaaa ctttttagac
    11221 aaaggattag aagatttaag cgtaactaga acgacttttg actggggtat aaaagttcct
    11281 tttgatgaaa aacatgtaat ttatgtgtgg gtagatgctt tatgtaacta tataacagca
    11341 ttaggttata tgactgataa tgatgaagaa tttaaaaaat attggcctgc caatgttcaa
    11401 atagtaggta aagaaatagt gagattccat acaataatat ggccagcgct tttaatggct
    11461 ttaggtctag aagttccaaa acaagtattt ggacatggat ggatactatt tgctgatgat
    11521 aaaatgagta aatcaaaagg taatgtggtt tatccagaac ctataataga aagatatgga
    11581 atagacacac ttaagtactt cttattaaga gagtttgcat ttgggcaaga tggaagttat
    11641 actcatagaa attttgtaac gagaataaat tatgatttag caaatgattt aggaaactta
    11701 ataagtagaa ctgtagctat ggttgaaaaa tacaataatg gtataatacc aacagcaaaa
    11761 gtttcaactg attttgatgc tgacttaaaa gaacaagctg tttcaactag agaaaacttt
    11821 gaagctgaaa tggataaaat gcaattccat gaagcattag agagtgtatg gaaattagtt
    11881 agaagaacta acaaatatat agatgaaact atgccttggg cactagctaa agatgaaacg
    11941 aagaaaggtg aattagacac agttttatat aatttatgtg aatctataag aataatcgca
    12001 acactaataa atcctataat gaatgagact gctaataaaa tatatgaaca tataggaata
    12061 aaaggtcaag atgatataac tacatgggaa agtacaaaaa catttggtct tattggagaa
    12121 aatgtaaaag tatttaaagg tgaaccttta ttcccaagat tagatgtaga aaaagagata
    12181 gaagaattaa ctaaaatgtt ctctgggaaa cctccagtag aagaaaaacc tttagagcat
    12241 aaagaagaaa ttactattga tgatttagac aaaatagagc ttagagtagg gaaaataata
    12301 agctgtgaaa aacatccaaa agcaaataaa ttattagtat cacaagttaa gattggacca
    12361 gaaacaagac aaatagtatc aggaatagct gaatactata agccagagga tttagtagga
    12421 aaagaggtta cagtggtatg taacttaaaa ccagttaaat taagaggtgt agaatctcaa
    12481 ggtatgatat tagcagcagg tgatgatgga gacccatatg ttttaccatt tacacaaggg
    12541 gctaaagatg gatgcgaggt tcgttagtag gtaattaaat agtaaggaga ttaaagatgt
    12601 tatttgactc acatgcacat ttaaatgatg aaagttttga tgaagataga gatgaactta
    12661 ttggttcatt aaaagataaa ggtgtagatt tggttgtaaa tccaggagca gatatagaga
    12721 cgtcgataac agcaattgaa cttgcgaaaa aatacgactt tatatattca gcagttgggg
    12781 tacatccaca tgatgtatca aaactagatg atacagcaat agaaactcta agaaaacttg
    12841 caactgagaa tgaaaaagtt gtagctattg gagagattgg attagattat tattatgatt
    12901 attctccaag agaagaacaa aaagagtggt ttaagaagca aattgaatta gctaatgagc
    12961 taaaacttcc aataataata catgatagag atgcacatgg agatactttt gagataataa
    13021 agaatactaa aaatcctgaa ataggatgtg tacttcattg ttatagtggg aatgtagagt
    13081 tagctagaga atatgttaag atgggttgtt atatatcaat tccaggtacg gttactttta
    13141 agaataataa aaaaactaga gaagtagtaa gagaaatacc tctagaaaga ttattcatag
    13201 agactgattc accatatatg tcaccagagc cacatagagg aaagagaaac aatccttctc
    13261 aagtatcttt tgttgctgat aagatagccc aggaaaaagg gatatgttat gaagaagtat
    13321 gtagagttac aaaagaaaat gcaaagaaat tttttaatat aaaatagaca aattaaatct
    13381 tataatgata tatataataa gtcattataa gtataggatg agagtgcctc aaaatgagtt
    13441 ttttagttca tgaggcactc tttttttatg aaatcaaata tattttcatc atttcaacaa
    13501 tgaaaaagaa gtttattata ttttgagaca gtttgttttt gtttatttaa ttcatatttt
    13561 aaaatatatt ttcttaacat tgttaaaaaa gaatttacaa gatattcatt agaattaact
    13621 caactctaat attcacttaa cttaagttgt ttattatatt attaaagaga agtaaacgaa
    13681 aggtagatta aggaggttga attttgtata cagttgatag tactaagata ttgataaata
    13741 tgaacttaga gaaactagaa aagatatact caatgataaa agatacatca agtatttcta
    13801 taattaaaga acctaacttg gctacagtaa tggtaagagc taatgaaagt gtaaaaaaca
    13861 caacatttaa tttaggagag atattagtta ctgaatgtag tgtaaaggta gatgaaagct
    13921 tgggttacgg aatagtttca gaaaacaata ataagaaagc catttactta gcagttatag
    13981 atgcagtttt acatagcaat aacagtaaat ttgatgagtt aaagaattac ataaataaaa
    14041 gtgtatatga agagaactta aggtatgaac aagagattat tgatgaattt agcttgatta
    14101 ataaaacgaa agttcaattc aatgctatgg attaaatagg aggagaatca tggtaaatta
    14161 tacacaagaa atatatagaa agatgctaga tagtgcttca tttcctggga aattaaataa
    14221 tatagataat ataaatatag aaaataatac aaaactattg aatggagcaa ttggtatagc
    14281 aatcacttta ttagaccaag aagttacctt ctatatagaa aattatactc aaaaagatat
    14341 aaaaaatata agagcactta caatgtcaaa tcaaatagat tatagaaaat cagattatat
    14401 atttttagat attaattcag aagtggatat attacagatt aaaataggtt cttttgaata
    14461 tcctgatgaa agtgcaacta tagtacatca agtaaatgat ttatcaacgt actctcaaac
    14521 taagtatata aagcttgatt tgagtggtcc tggtataaaa tctaaaaata gtatatatat
    14581 aaatggaatt agagaagaat ttatagaaag attatctagc ataaataaag attatccaat
    14641 aggaatagat ttgattttag tagataaaaa aggagaaatt gcatttatac caaggtcatc
    14701 aaaattaagt tgggaggtat tatagaaatg gcttatgtag cagttaaagg tggagaagaa
    14761 gccatattac aggctaaaaa tatacttgag ttttataggg taaaaggaga tagcttgcct
    14821 atagatgtaa agcagattga ggaacaaatg tcttatgctg tagacaaagt aatgtctgaa
    14881 ggaagtttat acaacaagga actatcagca ttggctataa aacaagctca aggtgatata
    14941 ttagaagcct ctttctatgt aagagcttta aggtcaacaa tgcctagaat tacatattca
    15001 gaacccataa atacagaaga aatgagaata aaaagaagaa tatcagctac ttttaaagat
    15061 ataccaggag gtcagtatct tggggcaact agagactatg aaaatagaat attgaatgta
    15121 gaattattag aagaagatga aaaaaagaat agacatttta gagatagttt tataaatgaa
    15181 ttagaaacag tagatgaaat ccctgaattt acaaaaatat ctaatatatt tagaaaagaa
    15241 aatttattac aagaagaagt ttgtgaaaac aaattggaag aagttattga tgatattaca
    15301 agaaatagtt taagatttcc agtttctagg tcagcaaagt tacaggcatt aactagaggt
    15361 gaaagtggag tagtgtcagg ttttgcttat gctattgtaa gaggttttgg tgatgaacat
    15421 ccatatataa gtgaacttag aactggtaat gtatttataa aagtaaaaca tcccatctat
    15481 gaagatgaag aaatagtaat aggggatatg ctggttactg aatgtgaaat agtttcaaaa
    15541 gcatcacaaa ataagactga aaattctaaa actaattcgg aagataaaaa taagatgtct
    15601 ttaggatatg gtctttgtat ggggaataat gagaataagg ctatatctat ggccatacta
    15661 gacaaatctt tggagccaaa tagtgaaaaa ctagcacaag atgaagaatt tgtattgctt
    15721 catatagatg gaatagattc attaggattt atatctcact ttaagcttcc tcactatgta
    15781 gattttaaag cggatgtaga aagaataaaa tagtttgtgg aggtaagttt aggtgatata
    15841 taactatggt tttttagacg aaaacacaaa aaaagaaata agaagaaaga tattaaaagc
    15901 aatatcaata cctggttatc aagttccctt tggttcaaga gagttgccta tagctaaggg
    15961 atggggtact ggaggtttac aattaacact atcattaatt ggtaaaaatg atgtagtaaa
    16021 agtaattgac caaggaaatg atgattctac aaatgcttgt aatataagga gctttattgc
    16081 aagtgtaagt aatgtagaaa ccacaaaaga tacattagaa gctacattga ttcaaacgag
    16141 acatagaata ccagaagaaa aacttaaatc taatcaaata ctaatatttc aagtaccaat
    16201 accagaaacc cttagaatag tagaacctag tgaagtagaa acaagaagaa tgcattcaga
    16261 agaagattat agtaggatgt gggtatatct ttatgaagat atagttagat ttaatgatat
    16321 atctatagca gttgaatatc catgtaaagt aaatgataga tatttaatga atccatcacc
    16381 tatacctaga tttgatataa aaaaattaaa tatgtcagac aatttattct tgtttggtgc
    16441 aggtagagaa aaaagaattt atgctattcc tccatataca aaggtagaac ctttagagtt
    16501 tgaggattat aagtttgaag aggaaaagtt tgaaggaaaa tactgtagtt tatgtaacag
    16561 tacaaataca tttttagatg aagtatatga cagtgacact aatgaaaagt actatagttg
    16621 ctcagataca agttattgtg aaaaagttag attaaaaaat aacagtatag atgtgacaat
    16681 aggaggtact tggaatgagt aaaataaatg actctaaaag attagaaaat atagacaagc
    16741 aagtattaat aggaagaaat atcaatctta tttatggaga tgggtgtaaa aagtgttttg
    16801 aaagcacagg atatgaaagc aataatatat gtaagtattg tggttctata gttgcatgta
    16861 ataatgtaaa tttagaactt tatgaaggag aagtccttgg aattgtaggt gaatctggtt
    16921 caggaaaaag cactttatta aaaatactgt ttttccaaga acatgcaaat agtggagaag
    16981 tatatatatc ccattacaat aaagacacaa atatactaga gctttcagac caaaaaaaga
    17041 gatacataaa gaatcatttt atgggtattg tgtatcaaaa tccccacctt ggtttaaatt
    17101 tagactttag tagtggtggt aatatagcag aaaaattatt gatggcaaat ttatataatg
    17161 ttgaaaaaat aagagataga ggcaaagaac ttttaataaa aactaatata cctgtagaaa
    17221 gaatagacca taaaccaaaa tactttagtg ggggaatgca acaacgagtt caaatagcaa
    17281 aagctctttc aaataaccct ccaatattgc tattagatga ggttacaaca ggtttagatg
    17341 tttctgtgca agcggaagta ttggatttaa taagagaaat ccaaagagaa cttaagattt
    17401 ctatgatagt tgtatcccat gactttgatg ttataaagat gcttgctgat aggacaattg
    17461 taatgaaaaa tggaagtgtg attgagtctg gtcttacaga ccaaataatg gaggacccac
    17521 aacacccata tactcagcaa cttataaatt cattgctata aatatcgttt gtaaataagc
    17581 aaaatggggg tttttaataa aatgaaagaa actatacttg aagtaaataa ttttagtaaa
    17641 gactttgagt tacatgcatt gaacaagact ataacagcat gtagtaatat aagttttgaa
    17701 gtttcaaaag gtgagttttt aggaataata ggtaaatctg gagcaggtaa gtctaccata
    17761 ttaaaaagta tctataaaac atatatacca acaactggag aaataatttt taattcagaa
    17821 atatatggta atgtagacct ggctaaaatt ggagaccgag aaatgataaa tcttagaaag
    17881 aaagaaatag gatatgtatc acagttttta aagacacttc cacgaataac tgcaattgaa
    17941 ctggtagtac attctttaat tgagagtggg tttgaaaaag attgttcata tgatatggca
    18001 aaagatatac ttaaccaatt tgaaataaag gaaaatttat gggatgcata tccaaataat
    18061 ttttctggtg gagaaaaatt aagattaaat ttagctcaag ctatggttaa aaagcctaga
    18121 cttttgttac ttgatgaacc aactgcatca cttgataatc aatctaaaat atatgtaaaa
    18181 gaaaaaatgt tggagcttaa aagtcaagga actacaatga taggaatttt tcatgatata
    18241 gagtttatgg aaactgttat agataagacc tttactatgg caaaagggac tataagtgaa
    18301 agtggggtag cctagatgat aaaactaatt cataatgcaa atattgtatt agaagatatg
    18361 attttagaaa atggtcattt aatcatagag ggagatacaa taaaaaaagt atcaaatgat
    18421 aagattgatt acgcatttga ctttaatgag atagatgaaa taatagatgc aaaaaactta
    18481 tatgtaatac ctggtattat agatattcac agtgatgcca ttgaaaagga aatagagcca
    18541 agaccaagta cattattacc atttaatatg gcattttatg aactagataa aaaactacct
    18601 gcaaatggaa taactacagt ttatcattct atatctttag gggatggagt aggagttaga
    18661 agtattgata actctttaaa gatgattaaa aatattgatt catataaaaa tatagatagt
    18721 aagagcataa atcataaagt tcatttaaga tatgaagtgt tgtattatga aggtttagaa
    18781 aaggttttag aactattaga tgaaaataaa atagactact tatcaataat ggaccattct
    18841 ccaggacaag gtcagtatac aaatccaaca ttttataaag agtatgctac taaagtgtgg
    18901 ggagttacag aaaattatgt agatacatgg ttagatgatt tagtaaatct gcatgataat
    18961 ttagattgga ataaaatagc taatattata ggtatagcca aaactaaaaa tataaatgtt
    19021 gcatcacatg atgatgatac attagaaaaa atggatttca taaaaaatat aggcataaat
    19081 gtatctgaat ttcctataac tcttgaagtt gcaaaacatt caaaaaaatt gggtgttcta
    19141 acttgtttag gtgcaccgaa tattgtaaga ggtaaatctc ataataacaa tttaaaagca
    19201 atggatgcta tattggaaga ttgttgtgac attgtgtgtt cggattatct tccatcagct
    19261 atgataaagt ctatgtgtat agttgcagaa agaataaata atttaaataa agcagtcagt
    19321 ttatttacct caaatcctgc taaagcagtt ggtatatatg atgaaagagg tagtataaaa
    19381 gaaaataaaa aagcagattt agttttagta gatattgata gtgaatatcc aaaggtttta
    19441 aatactattg taaatggaaa aacagtttat aaaagggagg tataaagatt gctaacagag
    19501 ttacattgtc atacaagtat atcagataat aattttacta ctgaagaaat aataaaaaaa
    19561 gcagcagaaa agaatataaa tatcttagca ataacaaatc atgacacatt atctggattg
    19621 gatgaagctc ttgtgcttgg agagcattat ggaataacaa taataccagg tatagaaatt
    19681 tcagcctatg attataaaaa tagaaaaaga gttcatattc ttggatataa catagattta
    19741 aacagtcaag aaataaaaaa tttgtgcaat ccaatggtat gtgacagaca taaagcatct
    19801 gttaagatgg taaataaaat tatagattta ggatacaaaa tatctttgga agatgtaaag
    19861 aaatattcat caaagactgg aatatttaaa caacatataa tgaaagctct tatagataaa
    19921 gggtatacag ataatatata ttcaaatcta tataaagaat tgtttcatag aggaaacggc
    19981 aaggtatatg tatctttaaa atatgtggat tacagagatg caataaaagc tataaaaaat
    20041 tctggtggaa tttgtgtgtt agctcacccg ggtcaaatgg ataattttag cgctattgaa
    20101 gagatggtaa aagtaggatt agatggaata gaagtatatc atccatctca caacaaagaa
    20161 ctagaaaaag agtcgctttc ttatgctaag aagtataatc tagtggtcac aggaggctca
    20221 gattaccacg gattttattc tcaacataat tatgaacttg gaagcaagag cttaaataaa
    20281 gaagatttat ttaagtttag gttagcttta ggaggggtat tataaatgtc ttttttacaa
    20341 gtaaaaaatg taggtaaaag ttatggacaa gttaaggtgt taaaagacat atctattgat
    20401 attgaaaaag gagagtttat ttgtttacta ggtccaagtg gttgtggaaa gagtacacta
    20461 cttagaataa ttgcagggct tgaggataaa catggtggaa aaataataat aaatgataag
    20521 gatatgacta attcaccacc tgaaagtaga aattttggta tagtttttca atcatatgca
    20581 ttatttccaa atatgaatgt ttacaaaaac atagcctttg gactagaaaa taaaagcata
    20641 agtaaatcta atattgataa aaaagttaaa gaagttctag acgttgtaga attaagtgga
    20701 tatgagaaaa aatatccatc acaattatca ggtggacaac aacaaagggt tgcattagct
    20761 cgtgcgattg ctttagagcc agacttttta cttcttgatg aacctttatc tgcattagat
    20821 gcaaaagtaa gacttaaact tagggagcag attagaagtt tacatagaaa actaggcatt
    20881 acaactataa tggtaacgca tgaccaagaa gaagctcttt gtttagctga taagatggtt
    20941 gttatgaata gaggagaaat aatacaagtt ggaacgccaa aggaggtata taaaaatcca
    21001 gaaacacctt ttgtagctga ttttatagga acaataaatt ttatagatga tggtattaat
    21061 aagatagcta ttagaccaga agatataaaa gtagagtcta atagagattc taaagataag
    21121 gatataaaag tgggagaaat tttagatatc gaatttagag gatttaacta tagaattaca
    21181 gttgagtatc gttctaagca gatgaaatta gatgtagttt ccaaagttgc agaacaaatg
    21241 aaactatgta taggttctaa aataaacttt aagataccta aagaaggaat tgtacaatat
    21301 aaatcagagg gatgtgctta atagctaggg gtgaataaat gataacatca aaaaataaaa
    21361 gaagaataag tgatagcaca atacaaaaat atttcttgat tttttcggta attgtactaa
    21421 tagtatttat attatttcca ttagtatcat tattaaaaaa tgcatttatg gatacaagtg
    21481 gaaattttat aggaatttca aactttagta aatatgttga aaatccaagt cttatagcat
    21541 catttaaaaa ttcaattttt gtatctacag tctcatcttt aatatcacta tgtttagcat
    21601 ttatatattc atacgcaata acaagaacaa acataaagtt taaagatttt tttaaaacta
    21661 tgggaatgtt tccacttttt gcaccaacta tgttatatgg tatttcactt atataccttt
    21721 ttggaaataa gggaatcttt acaaccatgg gtctggaagt accactatat ggtccattag
    21781 gaataattat ttctcagatt ctatttacat ttccacaagc ttttttaata ttatctgtag
    21841 cactttcgat ggctgattac agactttatg aagcagcaga tagcttgggt gctagtgaat
    21901 ttaagaaatt ttgcaaaata acaattcctg gtataaagta ctcattactt agttcattct
    21961 ttgtatcctt tatacttgca tttacagatt ttggagcagc taaggtagtt ggaggaaact
    22021 acaatgtact ggccaccgac atatataaac aagtagttgg acaatttaac ataccaatgg
    22081 gagctactgt ttctatggta atgttaattc ctgtactaat agcatttaca ttagataaga
    22141 tggcaagtaa gaaacaaggt atgaccataa ctgcaaagtc tatgccatat aagattaagg
    22201 aaaataagtt tagagataga gtatttttaa tagtatgtag ttttataaca ttgctaattt
    22261 ttattttaat attcgtttca gttataggtt cagttataaa gttatggcca tataatttaa
    22321 gctttacaat ggaacactat acatttaaag gtattttggg aagtggaata aaaacatact
    22381 taagcagttt gaaaatatca actttaacag caatatttgg aactatattt gtatttttta
    22441 gtgcttatat gatagaaaag gtggataagt ttcctaaatt aagacaaaca gcttaccttt
    22501 tatcaatgat accaatggcc ttacctggct tagttttagg tatatcatat ataacttttt
    22561 ttaactcagc aagtaatcca ttaaattttt tatatggaag tacagcaata ttagttatag
    22621 taaatgtagt tcatttttat tcagtttgtt ttataacctc aaattcatct ttaaaaatgt
    22681 tggataaaga gtatgaatta gttgcaaaat ccataaatat tccattctat aaagtatttt
    22741 ttaatataac agttccaatg tctataacat caatacttga aatagtagta tattattttg
    22801 taaattcaat ggttactgtt tcagcattaa tatttttata tacacctcaa actcagactg
    22861 catcaatatc aatactaaag ttagatgaga taggatatat aggaccatca gctgctatgg
    22921 cagtattagt gcttttaaca aatataatag taagactttt gtacgaattt gtaacaaaga
    22981 aattaaaaaa taacacacaa aaatggcagc aaaaagatgt tgcatagggg aggtaaaaat
    23041 gaaatttaag aagctagttt ctttaggagt attatcaaca cttttattaa gtgtaataac
    23101 aggatgtagt actgattcat caggttcaga ttcaaagtct gatagtaaga caaaagggga
    23161 tttaacagtt tacacagcaa ttgaagaaga tagtatagag ccatatttag ctacgtttaa
    23221 agagaaatat ccagatatta aattaaatat tgttagggca tcaacaggag atataacagc
    23281 aagattatta gcagaaaagg ataatcctca agcagatgtt gtatggggag ttgcagccac
    23341 aagcttattg gttgcagatg accaggggat gttagaacca tatgctccaa aaggttctga
    23401 agaaatagag tctgcattta aagatgataa agaagttcct tcttgggttg ggatagatgc
    23461 ttggatgaca ggtataacag taaacactaa agaattaagt gataacaaca tcccagttcc
    23521 tagttcttac gaagatttaa taaagccaga atataaaggt cttatatcta tgcctaatcc
    23581 atcttcttct ggtacagggt acttaacagt atcagccctt atacaaatta tgggtgaaga
    23641 aaaagcatgg cagtatatgg ataaattgca tgagaatatt ggtgtataca ctcaatctgg
    23701 ttcagctcca gctacatcag cagcttcagg agaatatcct attggtatat cttttggata
    23761 tagaggtata aagttaaaag aggaaggcta tccagtagaa gtagtatttc caaaagaagg
    23821 ttctggatgg gatatagaag caaatgctct tgtgaaaaaa gataatataa aagaagcatc
    23881 aaaagtattt ttagattggg ctataagtaa agatgcaatg aacgaatact ctaagaacta
    23941 tgcagttact actatttcta caggaaatcc aataccagaa ggattcccta aaaagccatt
    24001 agagcaaatg atagataatg atttaaaatc agcagcaaaa aatagagaag atatactaaa
    24061 taaatggata tcaaaatatg atggtaagac agaaaaagag agttaagtaa aactatacaa
    24121 atggagtaaa aagaaagaat ttttttaagt agattttatt ataataagat aagttgagaa
    24181 taatataggt caagaaaagt gaatattcta taaaaatgta tagagtaagt ataccattca
    24241 gtttgaatgg tatatttttt atttttagag attaatttag caatagatat actacagttt
    24301 aaaatagtat attttaattt cattattaaa gtatagatgt tatatataaa gtaaataaga
    24361 tattaaataa ttataaacta aagtaaataa actattgagc gattattaaa aagatatata
    24421 taaaatttaa tttgagcagt ttgttatata ttataaaaaa agagaaaaat aaaaggtaaa
    24481 ttgtttctgg ataacttaaa attggaagta agaatattta actagagaag aattatttaa
    24541 gttcaggtta gctctaggag tagctgattt tataggaaca atagatttta tggatgatga
    24601 tataaacatg atagcaatta gaccagaaga tataagggta gaatttaata gagatttcaa
    24661 agaaattata gacctcaaac tcagaccgca tcgatataaa aactaaagct agatgatata
    24721 gtgttgtata taggaccatc agctgttatg gcagtattag tgcttttaac aaatataata
    24781 gtaaaacttt tgtatgaatt gataataaaa aaattaaaaa ccaagacata aaaatggcaa
    24841 caaaaagaag ttgaataagg gaggtaaaaa tgaaatttaa gaagttagtc tctttgggaa
    24901 tattatcaac acttttattg agtgtaataa ctggatgtag taatgtttca tcaggttcaa
    24961 acttaaagtc taataataag acaaaaggag agttaacagt ttatacagca attgaggaag
    25021 atagtataga tacatactta actacattta aagagaaata tccagatatt aaattgaatg
    25081 tacttagatt atcagtagga ggtataacag caagattatt agcagaaaaa gataatccta
    25141 aagcagatgt gttatggggt gttgcagcta caagtttgat aattttagat gacaaagaaa
    25201 tgctagagcc atacgctccg aaaggctttg ataaggtaaa tcctgcattt aaagatgata
    25261 agaaagttcc ttcttgggtt ggaatagatg cttggatgac tggtataaca gtaaatacta
    25321 aagaattaaa agctaaaaat atatcagctc ctagttctta tgaagattta ataaagccag
    25381 aatataaaga tcttatatct atgcctagtc cagcttcctc aggaacagga tatttaacag
    25441 tatcagaact catacaaatt atgggtgaag aaaaagcatg gcagtatatg gataaattgc
    25501 ataaaaatat tggtgtatac actcagtctg gttcagcgcc agctatatta gcagcttcag
    25561 gagaatatcc cattggtata tcttttggaa atagaggtat aaagttaaaa ggtgaaggtt
    25621 atccagtaga agtagtattt ccaaaagaag gttctggatg ggagatagaa tcaaatgcac
    25681 ttgtgaaaaa agataatata aaagaagcat caaaagtatt tttagattgg gctataagta
    25741 aagatgcaat gaatgagtat tctaagaatt ttgcagttac tacaattgac acgggaaatc
    25801 cggtgccaga aggatttcca aagaatccat tagaacagat gatagataat gatttaaaat
    25861 cagcagcaag aaatagagag gctatactaa ataaatggat agaaaaatat gatggaaaga
    25921 cagaaaaaga gagctaagac ttacaataaa atttagtaca aaaagcgcct agaatataag
    25981 ttttatatct aggctctttt gatatattta tttaaaatga atatttctat ataaaaataa
    26041 atagtttagt accttgatta aattaaataa aaaccttaaa ataaagagat gtaaagaaaa
    26101 actaaaaacg aataaaaggt gaatttatat gataaaagaa ataatagtag tagagggtag
    26161 agatgacgtt acagcagtta agagagcaat agatgcagaa cttataacta caggtggatt
    26221 tggatttcca aaaggtgtaa tggagcgtat aaaagctgct aatgaaagac gtggtgttat
    26281 aatatttaca gatccagatt ttgcaggtga aaaaataaga aaaaaaatag catcagaagt
    26341 tccaggatgt aaacatgcat tcctaccaag agaggaagct aaaaaggatg gagatatagg
    26401 tattgagaat gctactcctc aaagtataat agcagctctg aataaagtta gaactgaaaa
    26461 tacagaaaaa agagatgaat ttaagcaagt tgacttaatt agaaatggtc ttataggtaa
    26521 tgaagaagca tcacttagaa gagatgcact tggaaaaata cttggaattg gatatggaaa
    26581 tgcaaaacaa tttttaaata gattgaataa ttatggagtt gaaagagaag aatttataga
    26641 tgcattaaaa caaatctaaa cgtaatgttt aatgtatgaa aaatatgtat ataaaataaa
    26701 ttgtggaatt acggttaatt taagataaat tatttataat atatacctta ttttaaatca
    26761 atgtaaatac atataaataa gtataattaa taaaattaaa tatcaaaata agttaaaaag
    26821 gagtaaataa tggatagact atcttcacat aatgcaacaa aggaagtagt acaaaaatat
    26881 aattttaaat tttcaaagtc tttaggtcaa aatttcttga tagatagtaa tataattgat
    26941 aaaatcttat ctggagctag aatcacaaga ggagataata tcatagaagt aggacctggt
    27001 ataggaactc ttactcgtga gatgggtaaa atagcagaaa aggtagtagc tatagaaatc
    27061 gatagaaatt taattcctat attgaaagat accttgtcag atttagataa tacagaggtt
    27121 gtaaatcaag atatactaaa agtagacata caggaattag taaaagataa attaaatggt
    27181 ggaccagtta agcttgtagc aaatcttcca tattatataa ctactccaat agttatgaaa
    27241 tttttagagg aagacatacc tgtaacagac atagtagtca tggttcaaaa agaagttgca
    27301 gatagaatga atgctattcc gggtactaaa gattatgggg cattatctat agctgttcaa
    27361 tactattgtg atacagagat tgtggcaaaa gctccaagac atatgtttat accacaacca
    27421 aatgtagatt ccacagttat aggtttacat gtaagagata aaagaaaata tgatgttcat
    27481 aatgaagaca tattttttaa aacagtaaaa gcatcctttg gacaaagaag aaaaactctt
    27541 cttaattcgt tgggaggtct tggttttctt aataaagatg aaataagaga aatattaaaa
    27601 gaagctaata tagacgaaaa aagaaggggt gaaactctta gtatagaaga gttttcagtt
    27661 ctttcaaata taataaatac aaaagtatct tctaaataga aggtactttt tttaattttg
    27721 ttaacatata ttgtttagag aaactgtgtt aaggggggat tgcagtgggt tctaaaagaa
    27781 agtttaaaag agactatata atactagaag ctaaagacat aaactttaga tacaaagaac
    27841 gagtactgcc aaaagctttt gcaaaagttg aagtaaatga tgaaaaagca attattgcat
    27901 tatatgtaga aaatctaaaa tatgttaaag atgggtataa agcagtagca ataaaagatg
    27961 accatggatt aatagactta ggaaatataa ttttaaatga acaaggaaga ggtgaatttg
    28021 ttttagattt agaagattct gatgatgaga taaaaggtat tgcattattg tatgaaagaa
    28081 atataccttt aattggattt aagggaaata agcttgaaaa ttatgaggat atattattcc
    28141 aagaggtaga agaagaagaa tatgaagagc tggaagaaga agaagacgaa gagatagagg
    28201 ataatgatga aagtgataga gatgaagata atgaagaaga agaatttatt atagaagaat
    28261 atgaagaaga tgattatgaa gactattggg aagatgatga agatattgaa gaaggagagt
    28321 taaaagcaag aacggaagta gaagattcta gtgatgagga aatagaagag ttcaataatt
    28381 ataaggaaat agaaaattat aatagggtta aagtacagga agaatatata gacatagaat
    28441 ataatgagga agaagaggat gaagaagaag tttttgaagt aaatagagaa gaagataggt
    28501 ttgtttcctc aaaacctact aaagcaaaga aagttcaaaa agatcagaat aatattgaaa
    28561 aaataaaaag agctaatgga gtaagtcaag gagagagtgg aaataaacaa acaagtacat
    28621 tacttatgcc aagacaaata aaaaaaggtt tgaaattatt taaagaggta aaaccttttg
    28681 taacagatta tatagataag acaagatggt ggaaaataga gataaatcct acaacattgt
    28741 gtggatatac aatgccttat ttaggatatt taaacgtgtt gaattacacc atgtatagtg
    28801 atgcagtttt acattcatat aaatacagac actatttatt tggagttcag tatgatgaat
    28861 ataataagag aaaacattat atttatgcta tcccaggaaa tagaaatgaa cagccagaca
    28921 atggaagcac aggattttta agatatcaag cttgtgataa tagaacaaat agtttaggat
    28981 attggctatg ttttatagat tctagacaaa gaaatatagt taggtaaaaa taataaaaat
    29041 gaaaaaattt agattcaatt cttattttac tgaaaaaatt aatgaaatgt agtacaaaac
    29101 tttaaaaact attgataata tttaaatatt acactacaat atatcttgaa atacctatta
    29161 tattatggag gaaaattatg ataaacgagc aaagaatttt aaatgagttt cttgaattag
    29221 tacagataga tagtttatct ttaaaagagg ggaatgttgc taaagtatta gttaaaaaat
    29281 tagaagaaat aggttgttca gtagtaatag acaatgctgg tgaaaaagca aatggagaaa
    29341 ctggtaatat aatagctaca ttaaaaggaa ataaagaagg aaagaaaata ttatttagtt
    29401 cacatatgga tacagtaact ccaggtatag gggtaaaacc tatagtggat gaagcaaatg
    29461 gaataataaa aagtgatggt actacaatat taggttctga tgataaagca ggtatagcag
    29521 ctatattaga aggcttaaga tatataaatg aaaataatat agaacatact gatatacaag
    29581 ttgtattctc tatatgtgag gaatgtggat tagttggagc taaaaattta gactatggaa
    29641 aaatagattc tgaatatgca tttatattag atagtggtgg ttctccaggt gaaataatag
    29701 taaaagctcc tgcacaagat gtaataaatg ttaagatatt aggaaagact gctcatgcag
    29761 gtcttgaacc tgaagctgga ataagtgcta taatggtagc tgccagagca atagaaaata
    29821 tgaatttact tagaatagac gaagaaacaa ctgctaacat aggaattata aacggtggaa
    29881 cagctacaaa tatagtaaca ggagaagtta atataattgc agaagccaga agtctaaaag
    29941 aaaataaatt agatgttcaa actaaacaca tggtagagac ttttgaaaaa gctgcgaaag
    30001 attttggagc tcaaattgag atagatgtca atagagcata cacaccaata gatgttagtg
    30061 aggattctga aataataaaa cttgcaaaga aggctttttc aaacttaggt atagaaggtc
    30121 atactgaatc tacaggagga ggtagtgata caaatatatt aagtaagaat ggtatcgaag
    30181 ctataacttt aggaattggt atgaaaaatg ctcatacact aagtgaacat atagctataa
    30241 aagacttata tgattctgct aaaatggtag tggagataat aaaggaagca taaatttaaa
    30301 taatagtgta taatatatat atcgcctagc ttaagctagg tgatttttca ttttatagaa
    30361 gattgataat ctctattgaa agcaaagagt atacatttgc atataagaga gtgtttaatt
    30421 tatgttcaaa tgtaggttct taataatatt taaattgttt cataagggag gaataaatat
    30481 ggaaacaagg tatgaagaag caaataaaat aacaatacaa tcaatacttt ggaatgtagt
    30541 attaacgata attaaggtta tagctggtgt tattggtaat tctagcgcta tgattgcgga
    30601 tggattacat tcagcatcag atattataag ttctatagga gtactaatag gcaattatgt
    30661 atcttctaga cctggagata gagagcataa ttatggtcat gagaaagcag agacattagt
    30721 atcatttgtg ttatcaatat tgcttatttt cgtttctata acaataggta tagaggcaat
    30781 taaatcttta tttaacttag atgcattaag tgttccatca atattaccat tagtagtatc
    30841 agttatttca atcctgataa aagagtatca atatagaata acaataaaag ttgctaaaaa
    30901 gataaattca ccagccctaa aagctgatgc ttggcatcat aggtcagatg ctttatcttc
    30961 agtagctgct tttataggta taggtggttc tattttaggg tttaaaccat tagacccaat
    31021 tgcgtcagtt gtagtggcta tatttgtagc taaagtagga attagtatac ttataagttc
    31081 tgttaatgaa ttgatggatg tttcagttga tgaagaagag ataaaagaat taaaatttat
    31141 tgtagcagat acagaaggtg ttaaaaatct tggtgatata aagactagaa aacatggagc
    31201 tatggcatat gtagatttga ctatatgtgt ggatgaaaat ttgacagtta agcaaggtca
    31261 tgatattgct accaagcttg aaaaacatat aataaaacat atggaatttg taaaaggcat
    31321 aacagttcac gttgaaccat gtactaattg ccaaggaaat aagtgtaata attaattaaa
    31381 acttaaaaaa aagtgtaaaa agttatataa ttgttttatg attataaact ctaggggtgg
    31441 ttaaatgagc aagaaaagaa aactaaagaa aaaagctgca atattaatag gagtagttgt
    31501 tttctttata atatacttta tatcctttag aataggaata aatatggaaa aggataaaag
    31561 tgaagtgcca aagaaggtag aaaaagaaga agaagataat aggtctttaa ggactcaaat
    31621 aaaagagaag aagaaggttt atatatcaga taaaaatata gaaaacataa aaattgaaga
    31681 agatatgtgg gatgaaataa agttattttt ctcagatttt aagaaagtaa gaaatactac
    31741 ttcttcttac gaagcagttt atgaaggtta ttctgatgat ggagttaaat tttccactga
    31801 ccttaacttt tttagagtat atactgtaaa taaagaagaa tattataaag taccagttag
    31861 ttctaaggat gcttttaaga aacttttaga tgagagtata tatacttcgt ttgatctttt
    31921 aagtcattat aaagattgga aagaggttac tataactcat ggaaaagaaa ttaagaaagt
    31981 tcatagatgg aaatttgatg atttagcaca taagatgatt tcaaagaggg ttgtaggaaa
    32041 agttcaacct gagaaaagta aggaaagaag tgactataat tttactataa atataaaagg
    32101 tgataatttt gatgtaaaag ttgatacaat gggaaaagat tatgtaaaag ttacttctaa
    32161 gaaaaatgta tcttactatg aggttcatat aagtttattt gattacctta aaaatgagat
    32221 atttgaaatt ggaaagaaat aagactttaa gaaggctatc aaattagata tttgatagcc
    32281 taaattattt ttatatatta tttttcaacc aacaagtctg caaccttata aattggacca
    32341 gcaccagcag ttattactaa atcattatcc ttaacatttt cacgtaagta ttttactata
    32401 tcttcaaatt cttttatata aatggcatct acattgtttt gatataattt ctcaaccaag
    32461 tccttagaat gtatatctcc agggtctttt tccctagcag catatatatc tgttatgata
    32521 actttatcag cagcatagaa tgcctctgaa aattcaccta aaagagattt tgttctagta
    32581 taagtatgtg gctggaagat acaccataaa gttgattttt ttaatttttt ggcagcagct
    32641 aaagttgctt ttaactcagt tggatgatgt gcataatcat ctactactaa agcattctta
    32701 taataccctt tagtttcaaa tcttcttccg acacctttat aaatttttat attttttctt
    32761 atagtctcta agtcaatacc agaaacaaga gctgccatta tagcagaaga agcattgtat
    32821 atgttatgaa gaccatatac agaaagttca aattctccta aatctcttcc ttcatattct
    32881 attctaaata ttccatgacc actactgtca aagtgaatat cttttattac agcatcattg
    32941 tcagaatctc taccgtattt tataatagta gctttaacat catacaatat gtcatcaata
    33001 ttttcatcat cgccatttat tatgaaatag ccttctgggg gtaataattt tccaaatttg
    33061 ttaaaagaag ccttgatttc atctattcca gagaaataat caagatggtc ttcttcaaca
    33121 tttaaaacta tagatatctt tgggttaaaa ttaaggaaac tatctacata ttcacatgct
    33181 tcagttataa agtggttgga attacctatc ttaacattac cacctatcat acttaagtta
    33241 ccaccaacta gtatagttgg gtctaagtct gcatattcaa agattgtaga taacatagat
    33301 gttgtagaag tttttccatg tgttccagaa actgctatag aatttttata ttccctcatg
    33361 atttggccta aaaaagttgc tctgttcatt accaatttat ttttttcttt agcagccaca
    33421 agttcttcat tgtctggatg aactgctgct gtataaacaa ccatatttac atcatctgat
    33481 atattatctt ttttctgacc aatataaata gttgcccctt ggtccctaag tttgtctaat
    33541 aggtatgatt cgtttgaatc cgaacctgaa acttgataac ctttattgat acatatttca
    33601 gctaatgcac tcatgctgat accgccaatt cctataaagt gtatattcat aataaaacca
    33661 cctttctttt taattaagtc ctacaatatg aactatttct gtggtataat aatataatgt
    33721 tcaatatttt ataattaata tgcatataat attatatgta ttttattttt gaatataata
    33781 aaacataagt aatattatac cacaataaga attgttatgc attagttagt ttaacgttat
    33841 ataaaggtac ttgtaggagg aaataataat gaaatttaaa agaacagaga gaattggagc
    33901 aatagttaaa atactgtctg ataatccaaa taaaatatat actttaagtt attttacaaa
    33961 tcaatttaat gcagcaaaat caacaataag tgaagattta ttagttgtaa aaaatgtatt
    34021 tgagaagcta catttaggta aagttataac tatttcagga gcagcaggag gagtaaaata
    34081 tatacctaaa acttctatag cagaaaatgc agagttctta atggaattat gcgagagaat
    34141 atgtgacaag tctagaatac tatctggtgg ttttttatac ttgattgacc taatttacga
    34201 ccctacaata gctgctaaga taggaaagat attcgcatca aatattgagt atgtagatgc
    34261 agattatgtt gtgacaatgg aaacaaaagg tatacctatg gcacttatga ctgcaaaagc
    34321 tatgaattta cctctagtta taataagaaa agatataaag gtatcagaag gtcctacact
    34381 tagcatgaca tatgtgagtg gaaacagttc taaagttgaa agtatgagtt tgccaagaaa
    34441 agctcttaaa ccagatagta aagttataat tatagatgat ttcatgaggg gtggaggtac
    34501 tataaaagga atggtagacc ttatgaatga atttggtgca gaagttatag gtactggagt
    34561 attcatatct acaacgaatc cttcagaaaa aatggtaaaa gattatattt cattgattca
    34621 attggatgtt aatggagata aaatagtagt agaaccaaac ttaaagactt ttaaagatga
    34681 atatagaaat gaagatttag acgaagaaga agattcagaa tttgaatttg agatagatga
    34741 agattaataa aaaaaatatt tagaaaaata tgtaaaaata aaaagaggat atccctagtt
    34801 gttcatagaa ttatttaaaa aacagtttat attaatttat tccagcgata ataattttaa
    34861 tataaattaa tttctgtcaa aatcaaaggg ggatattttg gtatgaagat aactgacgta
    34921 agagtaagaa aattaacaga agaaggtaag atgaaatgta tagtttcaat aactttcgat
    34981 aatttgtttg tagtgcatga tataaaagtt atagaaggcc ataatgggct atttatagca
    35041 atgcctagca gaaaagtagg cgaaggaaat ttcagagata tagctcatcc aataaatgca
    35101 gaaatgagac aagttttaga agatgcagtt ttacaagcat atcatgaagc attagttcaa
    35161 tgggaagtag ctgctgaata ataataaata tataaaatgg agagagcccg aacatttagg
    35221 ctctttttaa atgtagaatt tctattaaaa tatgtacttt ttagtaaaaa agtgctatat
    35281 tattagtgat aatgtatatg ttgtatacaa attgttagat aaatgtatta taatgtatat
    35341 tgattaagag aataatacga ataaaattaa attagattga atggagtgta tcaatgaact
    35401 ttaaagctat aatccttgct gctggcaaag gaacaagaat gaagtctaaa tacccaaaag
    35461 ttatacataa agtatgtgga aaagaaatgg ttaaccatat tatagatgtt tcaaaaaaat
    35521 caggggtaaa agatactgtc gtgattttag gacatgaagc tgaggtagtt aaagaaaagc
    35581 ttgcagaaga aattataata gccatgcaaa cagaacaact tgggacagga catgctgtaa
    35641 agatggctaa agaatatatt aatgatgaag atacaatagt tgtactttgt ggagatactc
    35701 cacttataaa agaagagaca ctaaagagat tatttgaata tcatatagaa aataaatatc
    35761 atgctacagt tcttacaaca agagttggaa atccaacagg ttatggtaga ataataagag
    35821 ataagaaggg tgaccttctt aaaatagtgg aacaaaaaga tgcaaattca gaagaaaaga
    35881 tgataagtga gataaactct ggaatttatt gttttaatgg aaagagtctt agagaagcac
    35941 tagatttgct aaataataac aattcacaag gtgaatatta tttaactgat actgctaaaa
    36001 taatgagaga taaaggatta aaagttggtg catttgcagg ttcaactatt gaagaactta
    36061 tgggcgttaa ctcaagagta gaattatcaa aggcagaaga aattatgaga cgaagaataa
    36121 atgaatctca tatggtaaat ggagtaacta taatagacac taactctacc tatatagaat
    36181 ctgatgttat gataggcaat gatactataa tatatccagg tgttatgtta caaggaaaaa
    36241 caaggatagg ttcagattgt ataattggaa tgaattcatc tataacaaat tcagaaatag
    36301 gtgatggtac agaaataaaa aattcaacta taattgatag taaggttgga gaaaattcta
    36361 ctgttgggcc atatgcatac ttaagaccaa agagtgactt aggaaataat gtaaaaatag
    36421 gcgattttgt agaagtaaaa aatgctatta tagaagatgg ttcaaaagca tctcaccttt
    36481 cttatatagg agatgcacat gtcggtaaaa atgtaaatat tggatgtgga gtagtatttg
    36541 taaactatga tggtaaaaat aaatttaaat caatagtaaa agacaatgcg tttataggtt
    36601 caaattctaa tttagttgca ccagtagttg tagaagaaaa aggatatata gcaacaggtt
    36661 caacaataac acatgatgtc ccagatggtg ctttggcaat agcaagagaa agacaagtta
    36721 tcaaagaagg atgggtagaa aaaaagaatc aaaaagacga ccaaagtaag taattatgta
    36781 gtttattatt ttggctaaaa aatttagctc gaaattatta taaattatat tcattagtat
    36841 tttaaaattt tcaggagggt tacataaatg aatactagcg gaagcgagat taaaattatt
    36901 gcaggtaatt catcgaaaga gttagcacaa aaaatagctg actatatagg tgtatcagta
    36961 ctagattgtg aagtaggtac atttagtgat ggtgaaatat gtgtaaacat gaatgagaca
    37021 gtaagaggtt gtgatgtgtt tgtagtgcaa tctactaaca gcccagtaaa tgataactta
    37081 atggagttat taatcttaat tgatgcgtta aagagagcat cagcaggtag aataacagca
    37141 gttattcctt actatggata tgcaagacaa gacagaaagg ctaaggcaag agatccaatc
    37201 actgctaaat tagttgcaaa tttaataact gctgctggag cagatagagt attaacaatg
    37261 gatttacatg cagctcaaat acaaggatat tttgatatac cattagacca cttactaggt
    37321 ggaacaatat tagcaaatta ttttaatgaa aagaaaatag aagatttagt agtagtatct
    37381 cctgacttag gaagtgttac tagatcaaga aaatttgcta atactttaaa tggagaagtt
    37441 ccaatagcta taatagataa aagaagaccg aaagctaatg tatgcgaagt tatgaactta
    37501 ataggtgatg ttaaaggtaa aaatgttata ctattagacg atatgataga tacagcagga
    37561 acaatagtta atgctgcaaa tgcacttaaa gagtttggag caaaagatgt ttatgcttgt
    37621 tgtactcatg gtgtgttatc aggtccagct attgaaagaa ttgctaattc agaaataagt
    37681 gagttaatag ttcttgatac tatacaactt cctgaagaga aaagaataga taagataaag
    37741 ataaaaacag tagctccttt atttggagat gctataagaa tgatattctc taatgaatca
    37801 gtaagtaaat tattctaatt tattgtattt atgagagttg tttaaaagga tataaacctt
    37861 ttgagcaact cttttttgat tttataatta tggaatgtta tttttttctt gttagaaagg
    37921 tatatattat tgtaaaaaga gattatagtt taaaattatg tatatttaag taaaataaac
    37981 ttaataaagg gcatattatt caaaatatta tgaatataaa aaatattaca aaaaagtatt
    38041 gaaaaaattc agattatgta gtattatgta aatataaata aagaaagagg tgtttccaat
    38101 gggaaggtta gaagatgaac ccctaataat taaatgattc agtcacaatc taaagtgaat
    38161 ataaaaatct attgaaagtt tatttataag aattgaaaat agtatctatt ctatctttag
    38221 tgtttgtgag agggttctgg attatataag attactgtaa agagtaattt tgcacaataa
    38281 gcatatctgt aaatgaagag tttcgtttat ataatgattg tggctgaatc ataactataa
    38341 tagatagaat gtttataata gatgatttta taaaatacta tattgtaata gcttttagct
    38401 ttcaaataaa tattagcaaa ggatggaaat gacaatgata aaactaaatg ataatttata
    38461 aatatctcct tacgatatat aataattgta gggagatgtt tctttttttt gtagagtata
    38521 atttttctag aaattctgtt tcaatatgta aaaagttggt atatataaat agtataaaca
    38581 gtgttgctaa aatatggtag atattatata atataagtgg atatgtatat acattatgag
    38641 ttatataatt tgaatttaat aaaatagaaa cgttgattta tgttctgtaa tgtgggcacc
    38701 ttagagcata ttgagttagt ggtgcaaccg gctatgaaat tgtatttatt tataaatact
    38761 attattttca tagctttttt tatttaaaaa atggttatat gttagaagta aatttggtta
    38821 gtacgtttaa ataattttac ttagattttt aaccagatat attataagta agtattaatt
    38881 aaaaaattta agggggaata aaaatgaagt taaaaaagaa taaaaaaggt ttcactttag
    38941 tggaattatt ggtagtaatt gcaattatag gtatattagc agtagtggca gttccagctt
    39001 tatttagtaa tataaacaag gctaaggtag caagtgttga gtctgattat agttcagtta
    39061 agagtgctgc attatcttat tattcagata ctaataagat accagttaca ccagatggtc
    39121 aaactggttt aagtgtttta gaaacttata tggagtctct tcctgataaa gctgatatag
    39181 gtggagaata taaattgatt aaagttggta gtaaattggt attacagata ggtacaaata
    39241 ctgagggagt taccttaaca gaagcacaat cagcaaaatt attgagtgat ataggtgaaa
    39301 ataaaatata tacaaatgca gctcttagtg ctaaattaac atctactaca aaggtaaata
    39361 atgaagcttt atatatagtt cttatagata atattgtaat ggatcaacaa ggagcttaaa
    39421 agtaaattgt tataatgaaa aatataataa aaaaacagga agaaaatctt cctgtttttt
    39481 tatactattt tctttaatgt tcaattatga atgatgatat aattgagata gtaaaggagt
    39541 gaaacctgtg gctaaaaaag ttagaatagg agacaaactg gtcgaaaaag gatatataac
    39601 agaagaacag cttaaatggg cactatcaga acaaaaaaac agtgggaaaa gactaggaga
    39661 atttctagta caagaagggc ttatagatag taacttacta ataagtgtat taaaagaact
    39721 cttggatata gaaagtatat ttttagaagg gacagaaata gacactttag ctacaaaaat
    39781 ggttccagaa aatatatgca aaagatatac tgtatttcca tttaaaattg atggaaataa
    39841 aatatgtcta gccatgtcag acccacaaga cagagaagca gttcaagatg taaggcgtat
    39901 gtcaggtaaa gacgtagaga tatttatatc aagtacagaa gatataaaca aagcaatagg
    39961 tcatgcttat gcacattcag aaataaataa agcaatgact gagtacaaca aaaatagaac
    40021 tggtggagta agagaaacag taatacttga agaagatgta aatgctgctc caatagtacg
    40081 attagtaaat aacatactag aaaatgctgt tagaatggaa gcaagtgata tacatataga
    40141 acaaagtgaa aattacatgc gtgttaggtt taggatagat ggaatgttaa gagaatatat
    40201 gaggatgaac tcagcaccat ataaggcagt aatcagccgt atcaagataa tgtcagatat
    40261 aaatatatct gaaaagagaa taccacagga tggtagaatc tatttaaaag tggataataa
    40321 acccatagat tttagggttt ctacaatgcc aactaacagg gatgaaaaga tagctatgag
    40381 ggttcttgat aagagtaatt ttatggttag taaagaagta ctaggaatag acgaacatgg
    40441 ctctaagata tatgatgaat tgataaacac tccttatggt cttatattgg ttgttggccc
    40501 tactggaagt ggaaaaacca ctacattgta ttcaatgtta aatcaactaa atacagaaaa
    40561 tagaaatcta ttaacaatag aagaccctat agagtatgaa ttacctggtg taaatcaatc
    40621 tcaaataaat gaaaaggcag ggcttacttt cgccagcgga cttagagctt ttatgcgtca
    40681 agacccagat ataataatgg ttggagagat aagagatact gagacagcag aaatagcaat
    40741 tagagcttct cttacaggac atttagtttt aagtacatta catgcaaata cagcagttgg
    40801 agcaatttca cgtcttttag atatggatgt agaaagtttt ttaataactt catctgtttt
    40861 aggtgtaata tctcaaagac ttacacgaaa aatatgtgag cattgtaagg tttcatatga
    40921 agcagatatt ggagaaaaaa aggctcttgg tattgatgta aatgaatcag taactattta
    40981 tagaggaaaa ggttgtgaaa ggtgtaataa tactggatat aaaggacgtc taggtatatt
    41041 tgaaatgctt gaaattactc cagaaataaa agagttaata gattcatctg caaatcaaag
    41101 agaaatttta aagatggcta gaaaacaagg tatggttagc ttaaaagagg atatagttaa
    41161 aaaggtttta aatggaaaga caacagtaga agaaatgatt agaataattt tgatgactga
    41221 ttaaaggatg atattatgaa aagttttaaa tacacagtaa taaaagagga cggaaaaaag
    41281 caaactgatg tgattgaagc caacgatttt aatgaagcta gaaatcttct tagaaagaga
    41341 aatcttagag ttattgaaat caaagaaagc aaaaataaaa atataagatt atctagtaga
    41401 aagagaaaaa aagacttagg agctgaccag ataagccact tttgtagaca gtttgctatt
    41461 atagtatctt ctggtataaa tagtatttct ggattagaaa cattagctag aaggtcaact
    41521 aacattacat taagagaaga aattaatcgt atagtagcag aaataaaagt aggttctact
    41581 attgcagatt caatgctttc atcaaaatca aagtttccaa agttacttgg tgctatggta
    41641 gctacaggtg aagctacagg taaattagat gaagtattaa aaagtatggc ttcattttat
    41701 gcaagtgaac acagggttaa acaaaagctt agaaatgctg caacatatcc attaatagtt
    41761 ttgatttctt catttataat gatttttata tttacaacat ttatggtgcc taagatgatt
    41821 aattcaatta caacagtagg agcaactctt ccacttataa caagaattgt tatggggttt
    41881 ggtatgttta tgaagaagtt ttggataata gtacttttag ttattatatt atttatctat
    41941 cagtttaaaa aatatttaaa aacgtcagtt ggaagggctc ataaagatag agttataaac
    42001 aagatacctg ttttaggaaa aggaataaat tgtatggtag ctacacgatt ttcaagagca
    42061 ttgtatctat ttgtatcaac aggataccca ttagttcaag ggcttgatta tattatagat
    42121 agtgtaaata acaccatggc agagaagatt ttagcatcag ctaaagatgg aataacaaga
    42181 ggagaaggct tagcagaaaa tttagagaga tatacgtatt ttgactctgt gttggtacag
    42241 atgatagcta taggggagca gacaggggaa ttagagaata taagtagaca gatggcagaa
    42301 ttttatgagt atgaatccga gatttattta aataggatgg cctcaatgat agagcctgtt
    42361 ttaataattg cagttggtat tatagttgcg atactggttg tatcaatatt tatgccaatg
    42421 cttagtatat atgatgccat gtaggaggga aaggacaaat gaacaaggtt tatgtatcat
    42481 attatggcga ttctatttcc atagttgagg gcagatataa acacgataag gataagtttt
    42541 atgtaaaaaa ttttaatgtg ttttcaatag aggatattgc acaagatttt tctaaggaaa
    42601 agtatgctct attgagatac gcattagaaa atgttaagtt aaaatcaaga catgtagttt
    42661 tttgtttaaa tacaagagat gtaattttaa aaccccaaaa acttcctaat atggacaaaa
    42721 aggatttaga cggatttatg aagctagaga tggacgaaat gatggctttg gagtcagatg
    42781 aatatgtatt ttcgtatgaa gtatctagtg aaacacctga taattcagat ggcgatgaat
    42841 caagcttaaa tcttattatt ggagctatac aaaaggaaga ggtaaatgca attgtagaga
    42901 taatgcatga atttgattta gtattagata gaatagatac attatcaaca gcttacttaa
    42961 gaatgcttaa aaatttagac tacaatgata taatggtaac caatataagt gacaatagca
    43021 caattataaa tatatataag aaagatactt tatttattag tgataatata cctataaaga
    43081 taactgctaa agatatggac atgcaattat taaatgtagt agaagaatca aaaggtctta
    43141 tgaattacta ttcgtcaaga aactttggta aggttacgga tactatatta atattaggaa
    43201 aaagatattc caataaatta atttatgaaa cttttagctc tgcattttca agctatgttt
    43261 ctcaaggcct tactgagata atggatatat ctgatatgat aactggagat atagatgaag
    43321 atgatataaa ttcaattgta gagcttttag gaagtatgat agaacctaaa gggaaaagag
    43381 attttgaaaa tataaacttt ttaccaatgg atatacttag aaaacagata aaagctaaac
    43441 aaatgaaaaa catactgaaa attgctccaa tagttatttt gattcttgct ataccttatt
    43501 tatgtttaat tttttcaaat aatttagcaa ataaggaact tgaaaatgtt aatggtgaaa
    43561 taagaaatat tgaatctgca tattatcaga ttggaaatat agaaaaaatg atacagagta
    43621 aaagcgaaga aataaaggta tatgatatgt taattgggaa aaaggtaaag tgggaaaatt
    43681 tattggatga tatagataaa aatactccaa gtaaagttga actaacaagt ttatcaacaa
    43741 cttatcaaaa tcttggaact aataataaag ctgataattc aaaaagtaat aagactacaa
    43801 cagataaatc aagtaacaat gaaacaaaat caagtacgaa aagtgatagt aatggagata
    43861 aaacagataa tgatttaaat gaagataaga ctacaaatgt gtcagaagca ttaattggaa
    43921 atagtgagac taatagtaat aacacagata aagatgataa aactccattg tatgataaga
    43981 taccaaatgt tataaatata gaaggaaatg ctaaagattc ctcttatgta ggtcaatttt
    44041 tatataaatt aaagggatta tactatttca aggatgttaa attacatagc ataaaaagta
    44101 atgcagaaga ttctaactat acatttagta tgacattata cctgaaagaa ggtgtattaa
    44161 ctaatgaata aagatatatt taaaaaagat ataaaagata tatttaaaat ggaagttagt
    44221 ctaaaaggga ttcttataaa ggttataatt ttattagcta ttttatcata tggttatttt
    44281 ggactttacc ctcaatatca gaaatatatt gctacaaaaa attctgtaaa acaggctact
    44341 gaaaaattaa atatatataa agagaaaact gcacttatgc caaaatatga aaaacaactt
    44401 gaagaagttg aaagtgaatt aaaagaaaaa agcaaaaatc ttttatatga tatgcaagat
    44461 ggtctttttt taataggttt agataaaaaa atgaaggctt ataatattga cttaaccagt
    44521 tatgacgttg gaaatgttaa agaatacgaa catttttatg gtatatcaac aacaataagt
    44581 gttagaggtg attatagaaa tgtcaaaaaa ttaatggctt atttagaaga acaaaaaaat
    44641 gttactcaaa tactagatta tacaatgact tcatatatag aaccagaaaa agaagaggaa
    44701 gaaacaacaa ataataagga tttaattaaa aatgtgaaca taaataaaga tacaaaaata
    44761 tactgggtgg aaggcgaaaa taagtggcat ttatataagg attgtccatt gataaaagag
    44821 ggagagattc taaaaaatga caaactttta gataggtcta ctaattatct atgtaatact
    44881 tgtgtactta gagctgcaac agaaaaagaa gcaaaaaaag aagtcgtagc tccaaaggca
    44941 gaaggtgtag tagatgctac atttaaattt ataatgtaca ctaaagagaa tactacaatg
    45001 atacttgata cagataatcc atcttcatgg agaccaggaa aatataatcc atttaagtct
    45061 agtgcgaaat aaagctaagt aagctttaaa gataggtgat gagtttgtac aaaaataatg
    45121 aaaaaggtct tactttatta gaagtaataa tagctgtttt tatactgaca atagttttaa
    45181 gtatttctta taaagtgttc aatggtataa catcagcagt aaaaaagcaa cagattatta
    45241 cagatgctca agtaaatatt aatctaatta ataagtatct aaatagagat ttggaaaact
    45301 gtaaagaact aactaaaact ggttcaggta ataattatga atacaatata gagatgccag
    45361 ataatgttgt aaaatatgaa gtttctatag aaactaaaaa aaatacagag gtatattctg
    45421 taacgagaat ccaaaacaat acaattgata cagaaaatga agttagagaa gagataatct
    45481 acaatcaacc actagttcaa aacaataaag aaatgaagga aacaccattt aaaatagaaa
    45541 agcaaactgg taaatctatt tatactgtaa gtatatacta taatgaatca gtgcaagaaa
    45601 gtcataaaaa tagcaattta aataacaaaa cttatacatt tgatgttatg tcaagaatag
    45661 ggtaataaga atttattaaa aaataagtag gttgataaaa tatgagtaaa aagaatagtg
    45721 aaagaggatt ttccttaatt gaagtgttag tagctatggc tattatggga attgtactat
    45781 ttgcattttt taatattatc aatactaata acaaagcaaa cactaaaaat gacacagata
    45841 taacctcctt aaactatgtc caaagtgaaa tagaaaatct aagagaaaag ataaaaagtg
    45901 gagaatttga ttttgatagt ttagataaac tagaagatgg aactgtcgta tatgaaaaat
    45961 taatagataa atcaaaaaaa gttgtatatg ataaagttct tagtgaaggt gatgtgagct
    46021 tatatgatac tccatatgaa aagattacaa caataaaaga tgaagatggt aatttaatcg
    46081 acaaaggaaa tattacaaat aagataaaga ctattgtaga agataaaagt ggtcagatat
    46141 ataaaatagc tgtaactggg aaaagcatga atgactattc aagtaaaaaa gaggttaaaa
    46201 ttgtaactga aatatttaaa gataaataat tttacttggg ggtgagattt tgaggaagtg
    46261 gaataaattt aaaagtgaaa gaggggcagc tttagtttta gttttggttg tagtagcatt
    46321 gctttctatt gttggattga tattttcaaa tcagatagct aatagaataa aatctacaaa
    46381 gactactaat gaaggtatac aagcaaagta tttagcagag acatgtgtgg aaaatagtat
    46441 tgataaagca tatgaaaaat tgtatgatga gcttgagaaa atggataatg agtttaaaag
    46501 tgaaaatcaa gaaaaatcca tatctaggtc aaaattaaga aatatatcag atgaagattt
    46561 taataatcaa gatgaggaaa atattgaagc agaaagactt ggatatatga ataatataaa
    46621 tttctattta aataaagctt cttcagactt ggaaaaagct agtatggaat tgaaaaagct
    46681 atatgattta gatatgttgg actatagaga cattgaatat gtagatgcaa atattatttc
    46741 acatagagat tctatcttag aaatttgcaa gaattatact tctggagata ttagtaaaat
    46801 aaatgaatat attctggaag aagatataga ctcaactaca ttgattgagg caaagttagt
    46861 gaataatgat attcttttaa aaatgttttt agaagaaaat aaaattgaaa atgaacattt
    46921 aaattcagcc ttttcacata cttataaggc attagataac atttctttgg cgatgcaaaa
    46981 tatgattgag tatagacata cgtttcatat agatgagcca aaagtagaag tatctaatgg
    47041 gattccagat tctcaacaat attatgaact aatacaaaat cctataataa atagtatgga
    47101 gtatatctgg aatagtaaat gggatacatt agaaaaccta ttggaaattt taccagatca
    47161 aactcaagga tttaattctt taagagttca tttgagaaat aatgtaagaa aatttgagaa
    47221 gttaagcgat aatatatcta gtggtaaaaa aaatacagca aaaaatttct taaagtataa
    47281 agagttattg tatgaaatat cagaccaatg taatcaacta aaaagtatgt cttatgagaa
    47341 aatacctgtt aaatatgata acatggcttt gataacaact tttgactata tacaaaatga
    47401 gcttttagca gagataaaat gcagattaaa agaattaaaa ccacaagaaa ttgataaaac
    47461 agaaggtatt actataaaaa taccttttta taaggctgac tacgacatga caaaagaagg
    47521 atggcctaaa ttaaaagaaa atggttcagg ggcggagtta agcttaatgg taactggtga
    47581 taaagatgga ataaaagaag tagaagttac agatggtaaa aaaaatatta ttggtttagg
    47641 tgttgaagaa aattcaaatt caaagtataa ggttgacgcc attgtaaact ttaatctaaa
    47701 tatagataca aatgtagttg gaaattatga tataaaagat aaaattttga ttaatcatga
    47761 tataagttca tacaaaaaag taaactaaat ataagaagca acttagtata aataaataat
    47821 aaaataattt tattatttac tactaaaaaa ataagtaaac taatagaaga tatggagagt
    47881 aaatattatg tatatttatg atttattaga gcaaggtata agactaaacg catcagatat
    47941 acacataacc gttggaacaa atcctgtagc tagagtaaaa ggtggatttg taaaactaag
    48001 tgaacaaata ttgacatcag aagtaacaat gcaaatggca aaagacatag caggggaatc
    48061 tatgtttaaa gtaatagaag aacatggaga agctgatttt tcagcttctc taaaaacagg
    48121 agaaagattt agggtaaatg catataggca aaaaggaaat tacgcaatag caataaggac
    48181 tataacagca gaaattccaa catttgaaaa attaggactt ccagagagta taaaatcttt
    48241 tactgaaaag cataaaggat tagttttagt tacaggtcca acaggaagtg gtaaaagtac
    48301 aacacttgca agtatgataa atataataaa tgaaaaacaa caaaaacata taattacact
    48361 tgaagacccg atagaatatg tacatcatca taaacaaagt ttagtaaatc aaagagaagt
    48421 aggaactgat acagaaagtt ttcattcagc ccttagagct attttgcgtc aggacccaga
    48481 tgtaatacta ataggagaga tgagagaccc tgaaactgtt tcaatagcat taacagcagc
    48541 agaaacaggt catttagtat tttcaacact acatacagtg ggggcagcta agacaattga
    48601 tagaatagta gacatgtttc aaccatccca acagcaacaa ataaaaacac agttatctac
    48661 agtttgtgaa ggtgtggtat cacagcagtt acttcctaca gcagatggga aaggcagaat
    48721 agcagcaatt gaattgatgt ttgctactcc agcaataaaa aacctgataa gggaaggcaa
    48781 aacatatcaa attccaaaca tgatacaaac tggagttaaa gtaggtatga aaactatgga
    48841 ccaagattta atggaacttt ataaaaatgg aaagattaca aaagatatgg cacttagtag
    48901 gtgtactgac caagagttta tgacaagaat gataggtgga gtaaactaca atggatatta
    48961 taatcgttaa tctatatgta tttatggtgg gtatagtgtt tggaagtttc tttaacgtct
    49021 gtatttttag gattccagaa ggtatatcta tttctagacc tccttctcat tgtatgagtt
    49081 gtaatactag actaaagcca atagacttaa taccagtgtt aagctattta atgagtggca
    49141 gaaagtgtag atattgttat gagaaaattt ctagtagata tgctatagtg gaattaatta
    49201 caggactttt atttttaaca gtatttatgt tatatggaat atctacatca actatttatt
    49261 atttggttct tgtgtcttta ctgattataa ttacatttat agatattgac cactttataa
    49321 taccagataa aatattggtt tttggagcta tgttttctat gatttttaac cttttattta
    49381 aagaaattcc agttaaggat tcaattctag gtgtttttat ttgtggagga agtgtctgga
    49441 ttatagttct tttgattgaa tttgtaataa aaaaagagtg tatgggtgga ggagatatca
    49501 aactatttgc aatgctaggt ttttacatgg gtgttaaaaa tggtcttttg acagccttac
    49561 taagcgttta tgtgggagca gtctatggaa tctgtgtaat aattataagt agaataaaag
    49621 gaaaggaata taattctgtt ataccatatg gaccttttat atctattgga gcattaataa
    49681 caatcttatg tggaaagcaa ttacttgaac tttatttttc tatggttata tagatgatag
    49741 tcaagttaaa taaagtttta atttaaaaaa atgaattaaa gtatttaata aggacaatat
    49801 tattattaac cctattacta aagtgctaca aactatggag tatataataa taatttcctt
    49861 attttttgca catttgataa ataaatctct atgtgttttt tgtgatagag aaaagaaaaa
    49921 tttatacaat acgtttttta tttacataat aactgtagtt ttatctgtat taatatatct
    49981 aaaatttggg attagtgtag aatgtgtaca atatatggtt ttaattccat ttttaataat
    50041 tatatccatt gtagattact acacaatata tgtatatgat ataacaatag ttagtggtat
    50101 aatagttcaa ggtataattt ttttggtctt tttcaatatg gttcaatttg attatataaa
    50161 tcatatattt ggactattga taggctttat tataccttat attattgcta aactaacaaa
    50221 aggattaggc tatggagatg taggtctcta tagcttatgt tgctttgcat tgggaaataa
    50281 ttatgggttt tatgtgatag ttttatcatt tattttagcg tttttgtttt ttattatttt
    50341 atacataact aaaatattta aagatgtaga tataagaaag caaattcctt ttacaccttt
    50401 tatttccttg tcaacaattt taataatatt tacagagtat aatatattta atttttatta
    50461 taatttgtta tacaaattta tataacagga ggtaagaaat gtacgtagta gtagggttag
    50521 gtaatccagg aaagaagtat gagaagacta gacataacgt tggatttgat gttatagata
    50581 ttcttgctaa agaatacaat attagtgtta ctaaaataaa gcataaagct ttgattggtg
    50641 aagggagagt aggtactgaa aaagtattat tagttaaacc acaaacttat atgaatttaa
    50701 gtggagaaac attaatagat atatataaat attataaggt tgatttaagt aatatagtag
    50761 tagtatatga tgatatagat ttagaagttg gaaagatacg tataagaaaa aaaggaagtg
    50821 gaggaactca taatggcatg aaatctataa ctaagtgcct aggttcaaat gactttccaa
    50881 gagtgagagt aggtgtatct aaaccagaag ctggtcaaga cttagcagac tttgtacttt
    50941 ctagatttag aaaagaagaa tctgataaca taaatgaagc attagaaaaa gcggcagatg
    51001 ctattgactc aataataaga gaaaatatag atatgtctat gaacaaatat aatggatagt
    51061 gagagggaga tttaaatgaa tgatgttttt ttatatcctt tgcaaaattc aaaagagtat
    51121 aaagatataa taaactgtat aaaaaataca aaaggctcat tattggttaa tggactttta
    51181 ccagtacaaa aacctcatat atcgtattct atatttaatg atttatcacg acaaatgatt
    51241 tttataacga gtagtgattt agaagcaaag aaagtatacg aagatttaag tttttatatg
    51301 gaagataaag ttgaatattt aggttttcaa gatatttatt tttatcactt ggatgcaaag
    51361 gacagaaacg aagaagcaaa gaaattaaaa gtattgttaa aactagcaaa taaagaaaaa
    51421 atcattttag taacttctat tgaggcagtt ttaagaaaat acataccaaa acaagttttg
    51481 ctcgatagtg tatctcatta taaggtggga gatagcttag acttagaaaa gttaactgag
    51541 aaattagttt cattgggata tgaaagagtt tcaaaaatag aggggtttgg tcaatttagt
    51601 ataagaggtg gaattattga tgtattttca cttgaatata caaatccaat tcgtatggaa
    51661 ttatttgatg atgagataga ttccatacga acttttgacg tatattcaca aaaatcaatt
    51721 gataaattgc aacaattctc tataactcca tctagagaat ttatttatcc cgaaaaaact
    51781 acagatgcat tagttaaatt aaaaaaagaa acaactaaaa atactgatga aggtacattt
    51841 caaaatatag attatatatc aagtaagact tattttgaag gtgcagagaa ctatatagat
    51901 tatatttatc cagaagaaaa caaaagtata tttacttatt tagcagatga tgcaatagta
    51961 tttatcaatg atataacgag acttaaagaa agatgcgaaa attatataaa tgagtttaga
    52021 gaaaattata aattaaatct tgaaagaggt ctggctatta aaaaccaagg taaattgtta
    52081 tatcactata cagatttaga gtacttagta aaagacaagt ctgtggtatt aaactcgcta
    52141 ttgccaaagt ctataaataa cttttctata aaatctataa taaattttga aagtagagaa
    52201 gttcctacat ttaatggaaa ggtagatttg cttgtagaag aattaaatcg gctgaaatat
    52261 aatggataca aaataatttt agcaacaaat accttagaaa gagcaaataa attaggaaaa
    52321 gatttattgg acaaaggctt agaaacgacc atttctaaag atagagatat tgaaattaaa
    52381 tcttcacaag ttataattgt acctgcacac ataaacagtg gttttcagta taaatctata
    52441 aagtttgttg ttataacaga taacgaaatg ataggtgttt ataaaagagc gtctaagact
    52501 agcaataaaa aagttaaaaa gggaaagaaa atagaatcct ttttagattt aagtgttgga
    52561 gactatgtag ttcatgaaaa tagtggtgta ggtagataca caggaattga acaaattaca
    52621 gtcaatgcta ttaaaaaaga ttatatgaaa atagtatatc aaggtggaga taatctatat
    52681 gtgccaatag accagatgga caaagtacaa aaatatattg gtgcagaagt agaaaaagtt
    52741 aagttaaata agcttggaac aaatgagtgg acgaaagcaa aagcaaaagt taaaaaagaa
    52801 attgaagata tgacaaaaga cttgattgag ctttatgcaa aacgtgaaaa aatacaaggg
    52861 tataagtttt caaaagatac accttggcag gcagagtttg aatcgttgtt tccatatcaa
    52921 gaaacagaag accaattaaa ggctatagaa gaaactaaaa aagatatgga atcaagtaag
    52981 gtaatggata ggctagtatg tggagatgtt ggttatggaa aaacagaggt agctattaga
    53041 agtattttta aagcttgtat ggaccaaaaa caagttgctg tattggttcc aacaacaata
    53101 ttggcccaac aacattataa tacattcaaa gagaggtttg aaaattatcc tttgagagta
    53161 gaagttttaa gtaggtttaa aacaccaaaa caacaaaaac agattattga agatgctaaa
    53221 aaaggattag tagatatttt aattggaaca catagaataa tatccaaaga tataaattta
    53281 ccaaacttag gtcttgtagt cattgatgaa gaacaaagat ttggagtaaa acataaagaa
    53341 gctttaaaga aaattaaatc tacagtagat gtacttacac tttcagcaac tcctatacca
    53401 agaacattac atatgtcttt aagtggaata agagacatga gtgttataga agaacctcca
    53461 caagaaagac atcctgtaat aacatatgtt acagagagta aggaaagcgt aattcaagat
    53521 gagatagaga gagaattaag tagaggtgga caggtatttt ttgtatacaa tagagttgaa
    53581 cacattgaag aaatggcaag tatgattcaa aaactcgtac cagatgctag agtggctgtt
    53641 gcacatggaa gaatgacttc taaatcatta gaaaatataa tcctaggatt tttaaataaa
    53701 gattatgatg tactagtctg tactacaata attgaaactg gtatggacat atcaaatgca
    53761 aatacaatga ttatatatga tgcagataaa atgggattgg ctcaacttta ccaattgaga
    53821 ggtagggttg gaagaagttc aagacaagga tatgcatatc ttttgtatga aaaagataaa
    53881 actttaagtg agatagcgga gaagagatta aaagctatca gagaatttac agagtttggt
    53941 tctggtttta aaatagcaat gagagacctt gaaataagag gagcaggaaa tattttaggt
    54001 tctcaacaac atggtcatat ggcagttata ggttatgatt tgtacgttaa aatgcttaat
    54061 gatgcaatta aaaaagtcaa aggtgaacct attgtggagg aaattgatgt tgaaatagat
    54121 ttaagtgtaa atgcatacat tccagataat tatatcaaag atgagttgat taaaattgaa
    54181 atgtataaga aaatagcttc tattgaaaac aaagaagaca tgttggatat acaagaagaa
    54241 cttgaggata gattctctga tatacctaaa ccagtccaga cacttcttac aatagcttat
    54301 ataaaatcgt tatgtaagat attaaaaata gaaaagataa gacaattaaa agatgaaata
    54361 ttattagttc caataacaaa gtatagaact aaacagaaaa taggttataa tatagttaca
    54421 gaattagaag aattattaga aaagatgtgc aaggtaaaat aacttgtaaa tttaagaagg
    54481 gatgttttaa atttgaaaaa agtaataaca ttggtaatag ctatgatttt ggtagtatct
    54541 gtgactgctt gcagttctag taaaggagaa actgtggcaa cagttgaagg tacaaagata
    54601 tcatcagatg aatttaaaaa aactatagct ctttataaag attctatgga acaaacttat
    54661 ggaaaagata tatgggataa ggaagttgaa aagggtgtaa aatacaagga caagtttaaa
    54721 gatttaattc ttgaccaact tataactaca gaagtaatat attctcaagc taaaaaagat
    54781 aacttacttc ctaaaaaaga ggatgttgaa aaaagtttta aagaattaaa agacgctatg
    54841 ggtaaagatg aaaaatataa agaacaactt aagaaattag gtatagatga tgagttttta
    54901 agagaccaac aagagaaaga tttagcaatg caaaactatc aaagtaactt tgctaaaaag
    54961 actaaaatat cagatgaaga aatgaaaaaa tactatgata cacataaaga tgaatttaaa
    55021 aaagatgagg tagaagcttc tcatatttta ttgaaaacag tagatgataa taacaagcca
    55081 ctttcagata aggaaaaagc tgaagctaag aaaaaggctg aagaggctct taaagaagtt
    55141 aaatcaggtg aggattttgc aaaagtagca aaaaaatatt cacaagatac ttcagcaagt
    55201 gatggtggta aattaggatt cttttcaagg ggtcaaatgg ttgctgaatt tgaagatgct
    55261 gctttttcta tgaaaaaggg tgaagtatct gatttagttg aaactcaata tggataccac
    55321 ataattaaag tgacagacag aataaatgag caaacatcat ttgaagatgc taaagaaact
    55381 ataaaagacc aactgttgaa aaataaatat caagaacaaa tagaaaaatt aactaaagaa
    55441 gctaaggtag aaaaagatga aaaagtaata aataaaatca caatctaaga cttaaaaaaa
    55501 gagtaatatg cttaaaaaag ctatatctgg ataagatata gctttttttg tatatttttc
    55561 ttaacaatgg taaaaataaa cttaaagtaa tttatggagg gattaaaaaa tatgaaagca
    55621 acaggtatag ttagaagaat agatgatctt ggaagggtag ttatcccaaa agagataaga
    55681 aagacattaa gaattagaga aggagaccct ttagagatat tcacagcaaa agatggagaa
    55741 gtcatactta aaaaatactc tccaataggt gaattaaatg aattttcgca agaatatgct
    55801 gaaacattag ctgaagtact aggatatgga gtgttgataa cagacttaga ttctataata
    55861 gctgtatcta agcttcctaa aaaagattac aaagaaaaaa gtataagtga tgagttagaa
    55921 gcaataataa gtgaaagaac agtaaaatat tcaaaagata aaaacatttt accattattc
    55981 aaggaagacc aaaaagaata tactagtcaa gttatcatgc ctataattag tgcatctggt
    56041 gactgtatag gttcaattgt agttgtttca aaggataaag atacaattgc agaaagtgaa
    56101 gaaaaatctt taaaaattgc tgctaacttt ttaggaaaac aagttcaata attttatcat
    56161 aaagaccttt tacatgaagg tcttttgaag tttttgtgta aaatattgaa tatagcatta
    56221 aaaatatggt atattaaagt ttgttatata aacagtatgg aggttatgtt atgaacaata
    56281 acaaaaataa agactccttt ctaaaaggag cccttatact tgggctagca ggtgtaatcg
    56341 taaaaataat gggtggattt tttaggattc cccttggaaa catgattggt tcagaaggaa
    56401 tgggatacta tcaggctgct tatcctgtgt atactctatt tttaacatta gctactgctg
    56461 gatttccaac agctgtggca aaattggttt cggaaaaagt tgcaattgga aattttaaag
    56521 gtgcaaataa gatatttaag gtatcacata cagttttatt cattaccggt ataatatcat
    56581 tttgtatatt attttttgga gccgactaca tagtaacaaa cgtaatgaaa aatccaggtg
    56641 cgttatactc tatgaaagcc attgctccag cattactatt tgttcctgca atgtctgcat
    56701 atagaggata ttttcaaggg agacaagata tgactaagat tgctgtgtct caagttgcag
    56761 agcaattttt tagagttgta ttaggtctta ctttggccta cttgcttatg aagagtctag
    56821 gtcagacttt tggtgcagca ggtgctatat caggggctac aataggttca atagcatcta
    56881 tgctttattt ggtgtttgct tatatgctag ggagaaaaga gcgtagagca gagatagatg
    56941 caagccaaag atttaaagat gaaagagtgt cttatatttt taaaaagctt ttaactgttg
    57001 ccattcctat aacaatagga gcatcagtaa tgccacttgt aaatatgata gataatgtta
    57061 ttgtaataag aagacttatg gaagcaggat ttacatacaa agtggcaaat tcaatgtttg
    57121 gtcaattaac aggtatggca atggccacaa taaatttacc agcagtcata acaactgcaa
    57181 tgagtatgag cttagttcca gcaatttcta aagcatatgc attaggaaat aagtcaaaag
    57241 ctagaaaaga tactaagagt gcagttaagg taactttact tatagtattg ccttgtgcgt
    57301 ttggtatggc ttctttagca ataccaataa tgggtctttt atttccacat gaaccatctt
    57361 ctgtaggaac tattttgttt actcttactc catgtgtatt atttttagga ttaatacaga
    57421 cattgactgg tataattcag ggaatgggaa aaccaatagt acctgtaatt gctttatgtg
    57481 ttggtatgct atgtaaaatt gtaataagtt atactttaac aggtatacca gatattaatg
    57541 tactgggttc agcatttggt acagttacag catactttgt ggcagccatg attaacttac
    57601 tatatgttaa aaaacacatg aatgtaaact tttctaaaaa agaatttata ataaagccat
    57661 ttataacagt tatgacaatg tttataatgg ttaagttgag ttatggtgct ttagttggat
    57721 tcttaggaaa cagcatatct acaataattg caatatgtgt tggtggaatt gtatatgtag
    57781 tagtaatact tggaataggt ggaattaaaa aagaagagat tctaactatg ccaaaaggtg
    57841 ataaattata taaattgtta aaaaaagtta aacttataag ataatatagg aatatatatg
    57901 caaataaagg aaatactata caaatagtaa atctccttat ttgtataata atataaaaat
    57961 aaagtgaaat ttgctaatag gagtgatgtt atgggtaaga taagtattgt aggtcttgga
    58021 ccaggagact attctcttat aagccaaggt gtgttagaat ctttaataaa tagccctaaa
    58081 gtttttttta gaacagagaa acatccaata attgataaac ttaaagaaac tatacaatac
    58141 acttctttag actactttta tgaaaaagag gaaaattttg ataatgttta tttgaaaata
    58201 tctgaattta tcatagaaga atcagcaaag ggtgacctag tgtatgctgt tcctggtcat
    58261 ccaagagttg cagagaagac tgtaagtata atagagagat tagccaatga aaagcacata
    58321 gcagtagaaa tattgccttc tatgagcttt gtagacgcta tgtttaccta tttggctata
    58381 gacccatctg agggatttaa actggtagat gcttttgaaa tagaaaattc atatatagac
    58441 ttggatacaa gcatgataat aactcaggta tatgataaat ttatagcatc taatgtaaag
    58501 ttaaaactta tggaacatta tgactataat caagaagtat gtatagtaaa tggagcaggt
    58561 gtcaaagatt tagaaagtaa aaagtttata aagctttgtg aattagacag aaatgaaaac
    58621 ttttttgact atttaactag cttatatata cccaaaagtt ctaaaaagat gtataataca
    58681 gtacatgact tagaaataat agttaataca cttagaagtc catctggatg tgaatgggat
    58741 aaaaaacaaa cacatcaatc attaaaaaat tctgttatag aggaagcata tgaactttgt
    58801 aatgcaattg ataataatga tatagatgaa atggtagaag agttaggtga tgttctttta
    58861 caggttatat tccattgtca gataggaaat gaggagggct actttgattt aaaagaagta
    58921 gtaaatggca tatgtaaaaa attaattcat agacatcctc atatatttag tggtgcaaaa
    58981 ttagatatgt ctaagtttga gaaaacttgg gaagaattaa agaaagaaga gaaaggcgaa
    59041 agtactataa cagatggcct tagaaggata ccaaaacatt taccagctct tatgaaggct
    59101 agtaaagttc aacataaagc agcacttgtc ggctttgatt gggacaatgt agaagatgta
    59161 tttaaaaaaa ttgaagaaga atatcaggaa ttacttgacg aacacagggt cgggaatata
    59221 aaatacataa aggaagagct aggcgattta ttattttcga tagtaaatct agctagattt
    59281 ttagacatag actcaggaga agccttgaac tgtactacag aaaaattcat aaatagattt
    59341 gactttatag aaaaaagtgc aatgaacttg aataaaaaat tagaagacat gacacttgaa
    59401 gagatggatg agttttggaa tcaggctaaa aaacaataaa attgtggaag gaaatttgtc
    59461 aaaaatctag aacttttatc acaaagatag aagtctatat tataaacatt tttaggaggt
    59521 aaatatcgtg aataaagctg aattagtatc aaagatggca gaaaaaagtg gattaacaaa
    59581 gaaggaagca gaagctgcgt taaacgcatt tatgagttct gttcaagatg cactagtaaa
    59641 taatgaaaaa gttcaattag ttggatttgg aacatttgag acaagagaaa gagctgctag
    59701 acaaggaaga aatccaagag atccagagca agttatagat ataccagctt ctaaagcacc
    59761 agttttcaaa gctggaaaag gattaaagga tataataaat ggataattag aaatcttgtg
    59821 aaaaagtgtg gataaatttg ccacactttt tctatagaac caaggaaggt gataattatg
    59881 agattagata aatttttaaa agtatctagg attataaaaa gaagaactgt tgctaaagat
    59941 gcatgtgata aagggattgt cactataaat ggaaaagttg ctaaatcttc ttcagaggtg
    60001 aatattggag atacattaga aatacaattt ggagagaaga agatgaagtt taagataaat
    60061 gaagtaaaag agcatgtatt aaaaaatgat gcaaaagaaa tgtacgaaat tttagaataa
    60121 aattaatagt cctctagtat attaatagta gtattattga aatatttact ggggggatat
    60181 tatggaacag aacataactt tgaaagatag atcaaagctg gttatttcgg gagtcgagca
    60241 catatactct tttaatgaca aaagagtaga gctcaaaact tctgtaggcg agatggtaat
    60301 tgaaggcgaa aacctagata tgagcaagct aagtatagac gaaaatataa ttagcataga
    60361 tggaactata aattctatgg tatatgcaaa gcctaaaaag ccacaagaga gtttcttgaa
    60421 aaaggtattt agatagatga taccttttac tcaagatgta agcatttttt atgctactat
    60481 ttatggtgga atactcatag gggtgttgtt tgatttttat agagggctaa gagggaattt
    60541 taaattcatc aattattttg ctataatctt tgatgtattg ttttggtttc tagctacggt
    60601 tataatattc gtaacaataa accttacaga attttttgat ttaagatatt atcattttgt
    60661 ggctttgttt attggtttta ttttatacta taacaccata agtaaaattg ttttatcaat
    60721 tatcaataaa ataattcgtt ttgtgagaaa ttcttttaaa aaagttacac attacatagt
    60781 cagtttttta aataatttgt attacgttat aatctattca ctacacctac tatttgatat
    60841 tatattttat ataccaaaca tatttatagc aacaagaaaa agtataaaaa gaaaatcaaa
    60901 taaaaaatta aagaacaaga aaaaatcaaa acctaagaag aaaaaaaata aaactaaaaa
    60961 aagggtgtag gaaaaatgaa cttaagaaaa aaattttcag gacagattat tgttgtcagt
    61021 ttatttttag gaatatcaat ttttagtatg atgacaggat ttgtatttga gtatacaaaa
    61081 gctaaggaat ataaaaaaga aatagcaagt ctaaataaac aattaaaaaa gactgaaata
    61141 caaataaaca gcttaaagaa agatgaaaaa tcatatgaag gagacttaga ggatatagca
    61201 agaaaaagat tgaatatggt aaaaccaaat gaaacagttt atgtagacat aaatcgttga
    61261 ttaaaacttg ctaataagtt tacagatgta ttgattttaa aatttaagat ttaataaaaa
    61321 agtcattcag ttaaggatgg ctttttgttt ttattgagga gggaatttca taatgaaagt
    61381 aggagctata gatattggga caaactcaat gagattattg atagcagatt atagagatgg
    61441 gaattttata aacagaaaaa aatttgttaa tacaactaga attggttatg gtgtggatag
    61501 taaaggatat ataaaagaag atgctatcaa aagaaatata aaagcattaa aagaattttc
    61561 tgataagtgt aatgatgaaa agtgtgaaaa aatttattgt atggggacat ctgctcttag
    61621 agacagtaaa aatggagatt actttgttaa attagctaaa gaagaaactg gaatagatgt
    61681 tgatatagtt acgggaatag aagaatcaaa tttgggcttt aagggtgttt tagaaggaat
    61741 acaaggtgat gatactatta ttgttataga tattggagga ggttcaacag aatttattgt
    61801 aggtgattca gaaggaatta aatttaataa aagtgagaat gtaggtgctc ttaggatgac
    61861 agagaggttt ttgaagcacg atattattga agatgaagag tttgaagcta tgagttcatt
    61921 tatatatgat gagattgaca aaacgttaaa tcatataaaa gacagaggat taaaaactct
    61981 tataggtata ggaggtacga ttacatcatt atcagcaatg aatcaagaat tagagattta
    62041 ctctatggaa aaaatacata atagtaaaat acacaaaaaa gaaatagaag aaattctaca
    62101 aaaattaata aagatgacat taagtgataa aaagaactta aaagggctac aagaaaaacg
    62161 tgcggatatt ataactgctg gtgtaaaaat attgaatata ataatggaaa aattagaaat
    62221 agaagaaata accgtaagtg aatacgataa tttggaaggc ttaatatgtc aaaagtcaaa
    62281 aaaaatgtat taatattttt tgatttttaa aaccgattat gacaaaaaaa attactcctc
    62341 tttgttacaa ttcttaatat aaacaaaaga ggaggttttt ttatgcaaag aagtgtagca
    62401 gttgtgaaga ataagactgt aaaaccaaat gtcataaaat taataagcgg atatattgat
    62461 tttactacgg cggcattcgc tgtgatggga tttttactta gtaggtctat tatagtagac
    62521 tctgtagctc ctttaggaat tgcctttttt atatgtgcat caaagattga taagtacaag
    62581 atacctgtat tcatatcaac attattagga atattgttat catctaatga ttttggaaat
    62641 gtagcaaaat atgctgtgtg ccttacaata tttatggcta tgaataaaaa attaaaatta
    62701 tcagattcaa ttgctaaggt tgcatttata ggtgcaataa tactacttcc aatctccatg
    62761 ggacaagctt tcttttcaaa taggtatgta tatggtcttc ttatagcagg agtagaagca
    62821 ataataatgt ttatatctat atatgtgttt tcttatggga taggtttaat ggccaatgtc
    62881 aacaatagga tgtctgtacg gacagaagaa gccatatcaa taagtttact gctaaccttt
    62941 agcataatgg gaataggaga tatatctctg tttggaatat caataaggac cattttatcg
    63001 accgtattga tattgctgac ctcaatagta ggtggagcta ccatgggagc atctagtggt
    63061 gtaattattg gtgtagcatc cattttaaat aatatgacat cagctgttta tatggggata
    63121 tattcttttt caggattaat aagtggagca tttaataaaa taaataaata tttctgtata
    63181 ctaggatata ttctaagttg gacaataata tacctatata cttctggtat tacttctaat
    63241 atgatgcaat taagagatat actattaggt tgtttgatag tactagtatt gccagagcga
    63301 ttatttaata agattgaaaa attaataaaa agtaatgtgg cttcaaatga aatcgtatac
    63361 gattatatta tgagaagcaa aaacctaact aatagcagat tgaacagtat ttataaaact
    63421 tatgatgacc ttgcagatac atttgataag ataagagaaa aagacaaagt gctagaccaa
    63481 agagacatag ctaatgtaat agatatgatt cataatgatg aatgtaaaag ttgtagtatg
    63541 agaagaatgt gctgggagtc aagatttaat catacataca ctatgatata taacattctt
    63601 gaaaaaattg aggagaaagg ggagttaagt ctaaacgata tacctaaaaa ttttagaaag
    63661 gaatgtatga aaccagagtc aatagtgaaa atatcaaatc actattacaa aatgtttgta
    63721 ttagattatg attggagtgt gaagttttca gaaagtagaa agttaatagc aaatcagata
    63781 agaagtattt caaaatccat taaatcctta tctcaagatt tagaaggcga cataatgcta
    63841 gatatagaaa aggaaaaaaa tatatatgaa cagttagaaa gatatgatat aacagttgat
    63901 aaagtaagtt acttaacaaa aagtaacagt gagtttgaaa tatcaataga aaagaaaact
    63961 tgccatgatg gatgtatgtg tgaagataaa attgtaaata taatttcaga cctagtaggg
    64021 gaaaatatgt ctgttagaaa aataggatgt cactgtttag gaggtaaatg caaggcaaca
    64081 ttcgttaaat ctcaaaaata taaggctgtt acagaagttt cagcaatgtc aagggatggg
    64141 catatccttt gtggagacaa ttacacatac atggagataa atgatggtaa atacatgatg
    64201 gctataagtg atggtatggg aaaaggtaaa aaagcatatg aagaatcttc tgccactatt
    64261 gatatactgg aaaaaatgat agatgcaaaa attaaagatg agatagtcat tgatactata
    64321 aataatatgt tgttgttaaa gtcttcagaa gagatgtttt caactctgga tttgggaatt
    64381 ttagatttaa aacgaggttg tttagaaact ataaagatgg gagcgtgttc tacttatata
    64441 aaaagagagg atggagaagt tgacttaata tcgtcatcat cattacctgt gggtatatta
    64501 tcagatgtaa aaattgatag aaaaaatgta aaagttaagg aaggagacta tgttataatg
    64561 gtttctgatg gaattgtaga tgcaggaaga aataacaatt taggagacaa ttggttaata
    64621 tacttcttaa agaatataga gactacaaat ccaaaggaaa tttcaaattt aatattggat
    64681 agagcattag agttacaagc gttacaaatc gaagatgaca tgactgtttt agttacgaaa
    64741 atatgtacaa aataaggttt acaagattat gtgtataaga tgtggataac ttgtgtataa
    64801 tatgttaata gacttttgaa aaaagtatag ttattaacaa aaataacata taaatcaaca
    64861 aaatttgttg ataagtatgg cagaaatgtt aataaaatgt aaaaaaagaa aaaacaaaag
    64921 ctattatcaa aagagattca tgttgaaata actaaatttc taattaaaga aaacctgtga
    64981 atatgttgat tattatgtgg ataactatta attcgatatt tatttatata gtatgaataa
    65041 ttgaataata tatctaaaaa aagccatcct attattaagt aaacttattg aaaggatggc
    65101 tttttatgaa tagaaaattg tgcaaagcaa taataccttt atttatttct attttttgca
    65161 tgttaataat aagtataaaa gctgaccaag gatatcaaaa gaataatgac agagcaatta
    65221 ctgtcatgaa taataatgat actgaagatg atgctgaaaa aaaacaagaa atagactatg
    65281 aaaaaacatg ttggaatttg caatctttgt ttaaaagtga tgaccaatgg aaaaaagaac
    65341 ttaagagttt tgataaagat actaaagagt tgaaaaatta cataggtaaa gtaacaaaat
    65401 cgccaacaca tttgtctttt gccttgaaca ttaaagaaaa acttgatata agactaaata
    65461 aactttctgc ctatgtaaaa ttaaaacaag atactaataa aaattcgtat aagtacttag
    65521 atatgaatga tagtatgagt aaatcctatg ggaattatat ggggatttgt tcagatttag
    65581 agttagaaat actaaaatta tcaaacaaag attacaagaa aattatttca aataaaaata
    65641 taaataggaa atatggtgca tatttaagag atataagaag gaataaagta cattatttgg
    65701 atgataaatc agaagatatt ctaagcaaag tatcttcaat aagtagtctt ccaagccaag
    65761 tgtatgaatt atttagaaat atggatagaa aaactaattt gacaccagct caatatgcga
    65821 gtgaattaga gtcatcagat agagaaaata gaaaaaaagc ttatcaagat gaacttataa
    65881 cttacaatga taatataaat acaattgcag gtttaattac tggtcaagtt aaaaagaata
    65941 ttttttattc tcaggaaaga ggttatgagt cttctttaga aatgtacctg gaatctgata
    66001 atgtagatga aaaagtatac aataatttga taaggactgt aaatagtaat atggacagtc
    66061 tacacaaata tatagattta agaaaaaaag tattaaaatt agataaggtt cattcatatg
    66121 atatgtttgt gcctatggtt aaggctgttg ataataatat taattatgaa aaggcacaaa
    66181 gtatagtata ttcagcgttg tcacctttag gaaaagaata caatgatgta gtatataaag
    66241 ctttcaatga aaaatggata gatgtttatt cacatgaaaa taaagtaagt ggtggatact
    66301 gcttatctgt ttatgaaaat catccatata tacttttaaa ttataataat tcattaggtt
    66361 cagtttcgac tttatcacat gagcttggac atgctgtata tgaatattta agttctaaga
    66421 atcagaatta ttttaattca aatccgtcta tatttactca cgaagttgca tctacaacga
    66481 atgaagcatt actttacgag atgcttataa aagaagctaa aggcaatgat gaaaaagctt
    66541 attatataac acagtattta gacttgataa aagatactct ttatacacaa actatgtatg
    66601 ctgaatttga aaaaactata cacgagttag tagaaaaagg aaaaagtgta aacgcattag
    66661 tattaaatga tgtttgggga caacttctta aaaaatatta tggacaaagc tatgaattag
    66721 accaattatc taaggtcgga tgggctagaa tcccacattt ttataatagt ttctatgtct
    66781 ataaatatgc tacaggttgt agtgcaggag taagttttgc ccaagacatc ctaaagaatg
    66841 gttcagataa ctatatgagc tttcttaaaa agggaagttc agattatcca ataaacttgt
    66901 taaaatcaag tggcataaat ttaactaata caaaacccat agaaaataca atcaaaaaat
    66961 ttgatagttt agtagcagaa cttgaaaagc tattataaac attattgtaa tccacatggt
    67021 aaatatatcg aattaatgat aaaatatact aaaagtttaa agtcctatca agataggact
    67081 ttttatttat taattagtgg gagatgattc tatgcaagtt aaagttaaaa aggctgtaat
    67141 accagcagca ggtttaggaa ctagattttt gccagctaca aaggcacaac caaaagagat
    67201 gttaccaata gttgataagc caactctaca atacataata gaagaagctg tggcctcagg
    67261 aatagaggaa atactaataa taacaggtag aaataaaaaa tctattgaag accactttga
    67321 taaatctgta gaattggaac ttgatttaga gaaaaaaggt aagaaagaat tgttggaggt
    67381 agtacaaaac atatctaaca tgattaacat acattatata agacaaaaag agccaaaagg
    67441 gttgggagat gcaatttatt gtgcgaggca ttttataggt gatgagccgt ttgcagtaat
    67501 gttaggggat gatattgtag ataatgatgt accttgtcta aaacaactaa cagatgcata
    67561 tgaggaatat agaactacaa tattgggtgt tcaaaaggta aatcaagaag atactaataa
    67621 atatgggata atagaagcaa aaaatataga aggtagagtt tacaaggtaa aagacatggt
    67681 agaaaagcca gagtcaggaa aagctccttc aaatattgct attttaggta gatatataat
    67741 aactcctgaa atctttgata ttcttaagga tttaccacca ggtaaaggtg gagaggtaca
    67801 acttacagat gctttaaaaa tattatctaa gaaagaagct atgtatgcat acaattttga
    67861 aggcaaaaga tatgatgttg gggacaagct aggattttta gaagctactg ttgactttgc
    67921 tctaaagaaa gaagacctta aggaagattt tataaaatat ttgaaacatg tatgtagtga
    67981 atttgataaa aataacaatg tgttatacaa taatacagat gaaaaaatag atttaattga
    68041 agtcaatgaa gctagagaac ttgaaattca aaaataatta atgaaaggtg atgtatggtg
    68101 gcaaaatcaa gtcagaaaag aattaataga ataatagctg ttgggattgt gggaatcctc
    68161 gtaataacga gtataacagc tgttttgagt atgattgcaa ctatgtaata agataaatga
    68221 cagcagttga tatacataaa tataaaaacc atatataact tgatgtagtc aaaaacttac
    68281 aatattttag ttatatatgg tttttagaat ttataaatgt aaaaaaaaat ttttataata
    68341 gttgcatatt ttaaaggaaa atattattat aagatataaa tatagtgata aatttataaa
    68401 aacgtgctaa gattggactt gaaatacagt aatatagtag gtaataatgt tttaaatttt
    68461 atttattgac cataatatat aaataatgat attattagac ttaactgttt aaataaaact
    68521 tttctttttc atgccttcaa tttccaaaat aagtatgtat ataaatgaat atatagatga
    68581 ggaggatttt tttgatttta gatgataaag tattagaagg attaggtagt aagaccttag
    68641 ttgagctacg agagatagct aaagaattaa aaataaaatc aattactaca tataagaaaa
    68701 atgagttaat tgagattata aattccaaaa gtaaaaatga ggaaaaagta aacgaagaga
    68761 ctaaagaaaa aaatgaagat attaaagaag acataaagaa tagaaaagaa aatatagagc
    68821 gtgaaagtat agaaaaagaa gttgaatata agagccctac caaatcatac aacaagaaag
    68881 aaatagatac ccaaaatatt tcccaaaacc aagaacatag aaatcaaaga aatgactata
    68941 ataagacaac gagtgtaaat gatagcaata agtcatcaaa tatatctaat agaatggtca
    69001 gaaataataa taaaaactat tatatgccta aacaagttga tgaatctaag atagtagatg
    69061 aatttaacac atcaaaagag gatgaagtag taggtgtact tgaaattctg ccagatggat
    69121 ttggtttttt aagaggttca aattatttgt ctactgaagg agatgtttac gtttcaccat
    69181 ctcaaataag aagatttaat atgaaaacag gagacaagat taagggaata actagacatc
    69241 caaaaagtgg agagaaattt agagcacttt tatatgttca aaaaataaat gatgaaaacc
    69301 ctgacacagc tatacaaaga aatgcgtttg agacattaac accaatattt ccagaagaac
    69361 gacttacact ggaaactaat agaaatgaaa tagctacaag aattatagat ttaatttcac
    69421 ctataggaaa aggacaaaga ggattgatag tagcacctcc aaaagctggg aaaacagttc
    69481 ttttaaaaag cgttgcaaat agcatagcta aaaatcatcc aaatgttgaa cttatagtac
    69541 tccttataga tgaaagacca gaggaagtta ctgatatgaa agaatctatt gaaggagacg
    69601 ttatatattc cacttttgac caagtatcaa gtcatcatgt caaggttgca gagatggtgt
    69661 taaatagagc tcaaagatta gttgaacatg gtaaagatgt agtaatttta ctagatagta
    69721 taactagatt ggcaagggca tataacctta caatatctcc tacaggtaga actttatctg
    69781 gaggtattga ccctggtgca cttcatggac ctaaaaagtt ctttggtgca gcaaggaata
    69841 ttagacaggg tggttctttg acaatattag gaacagcatt ggttgaaact ggttctagga
    69901 tggatgatgt aatatttgag gaatttaaag gtacaggaaa tatggagcta catttagata
    69961 gaaaattagc agaaaaaaga atattccctg caatagatat ttacaagtct ggtacaagaa
    70021 gagatgattt attgcttgat gatgaagaaa agactgctct ttggagatta agaagagaaa
    70081 tgagtaataa ttcagtaatg gaaattacag ataaagtcat tgaacttata aagagaacta
    70141 aggacaataa agagtttgta aaatcaataa agaatttgta aaatcaataa tacaaatgca
    70201 aatatggatt atataaacta atagaaaaat cacttgaatg gcataataag ttgtgctata
    70261 ataatgtagt tgataatgta aaaagaaagt taatataatt aattttttta aataaagaga
    70321 agaggtgact ataatgcaaa aggaaataca accaaaatac aatccagttg aagtgcgttg
    70381 tgcttgtggg aacacatttg ttgctggttc aactaaggac gaaataaaag ttgaaatatg
    70441 ttcagagtgc catccattct atacaggaaa acaaaagaac atagaaaaag gtggaagaat
    70501 cgacaaattc aagaaaagat tcaaaatgga ctaattttta taaaagtgga gttggaggaa
    70561 gccaactcct attttattac aaaaaaacat tcatattcta ctttaaattg tctttttgta
    70621 ttataataat aaatatgtaa aattgagtat tctaaataca ataaaatgag gtgagtggat
    70681 ggcaaaacaa gctgtaggtg ggcaagctgt tattgaaggt gtaatgatgc agtcaaaaga
    70741 caaaagagcg gtagctgtta gaaaaagtga cggagaaata gcactaaaag aagatagaat
    70801 aaaaagttgg gtaagagata agaatataga taagatacct tttgttagag gttcttttgt
    70861 tatgatagat acaatgattc aaggcataaa aagcttaaac ttttcttcag agttttttat
    70921 ggaagaagct gaagaggata aatttgattt atttataaag aaaattttta aagataaggc
    70981 aaatgatata attataatat tttcattggt catagcaatg ttactttctg ctggattatt
    71041 catttttata cctacattgg taggaggagc tttttctaaa gtaatgccta atgattttat
    71101 gcttaattta atagaaggaa tcataaggat agctatatta tttgcatata tagtattgat
    71161 ttcacgaagt aaggatatag aaagagtctt tcaatatcat ggagcagaac ataaatctat
    71221 atattgctat gaaaatgatt tagaacttac agtagagaat gctagaaaat ttaaaagatt
    71281 acatcctaga tgtggtacaa atttcctatt tatagttatg gctgtatcaa taatattgtt
    71341 tgcatttttt ggttggccaa atccaattct tagaatattt atgagaatta tatgtgtgcc
    71401 tatagtagca ggtttatctt atgaggtaat tagagttctt gggaaatatg ataatggatt
    71461 tactaaaatt attgcatatc caggaatgat gttgcaatat tttacaacaa aagagcctga
    71521 tgatgagcaa ttagaagttg ctttggaagc attgaaagca gtagtagatt agagaaaagg
    71581 atatttgtta tgacgataaa agatataatt attaaatatt cagataaact aaaagatata
    71641 agtgatactc caagattaga tacagagtta ttgttacaaa aaacattggg tgttgataga
    71701 ttatatattc acttaaatct gaataaagag ctaactgaag aacaaaaaac aaaatttatg
    71761 ggttttgcag aagaaagatt aaatggaaga ccaatagcat atatagttga aaatagggag
    71821 tttatgggat tagatttttt tgttaaggaa ggcgtattga ttccaagacc agatacagaa
    71881 actttagtag aagaaataat tgaaatatgt agagaaaaaa aagatgtaag tatattagat
    71941 ataggaactg gttctggagc tattacaata agtttagcaa agtacattga aaattctaaa
    72001 atcatgtctt ttgatatatc agagacagca ttagaaatag ctaaaaaaaa tgctattata
    72061 aatgaagttg gtgaaaaaat aaagtatatt aattctgatt tatttacagc aataagtgat
    72121 agtaacataa aattcgatat catagtttca aatccaccat atattaaaaa acaagatata
    72181 gaaactctgc acaaacaagt taaagattat gaaccatata atgctcttga aggtggagaa
    72241 gatggattag acttttatag aagaataaca gaacaaggta agaaatattt aaataagtgt
    72301 ggaatattag catatgaagt tggtcataat caagctgaag atgtaataaa tattatgaaa
    72361 agtaatggat ataaaaaaat atacacaaag aaggatattc aaggcattga tagagttgtt
    72421 ataggttaca atatatgata taatcaacaa ttgatatgtt acatttaatc gaggtgaaag
    72481 tatgttaaaa aaattagagg tattggaaga tacatataaa gacttaagtg aaaaaatagg
    72541 tgatccggat gtaataaatg atcaaaaagt ttggcagaaa tatataaaag aacatgctga
    72601 cttggaacct attgttatga aatacagaga gtataaaagc gttttagata gtataaaaga
    72661 atcaaaagaa attttacaag aagagtcaga tgaagaatta agagaattag ctaaaatgga
    72721 gttagctgag atggaagaaa aagtagcacc tctggaggaa gaaataaaaa tactattatt
    72781 gcctaaagac cctaatgatg ataagaacgt tatagttgaa attagaggtg gagctggagg
    72841 agatgaagca gctctatttg ctggtgattt atttagaatg tactcaaggt atgctgaaag
    72901 aagaagatgg aaaatagaat tattgagtgc aagtgatact ggagttggtg gatataaaga
    72961 agtatctttt atgataaaag gtaaaggtgc ttattcaaga ttaaagtatg aatctggagt
    73021 tcatagagtt caaagaatac catcaactga atctggtgga agaatacaca catcaacttc
    73081 tactgttgca gtattaccag aagttgaaga tgtagaggtt gaaataaatc caaatgattt
    73141 aagaatagat gttttccgtt cttcaggtaa tggaggacaa agtgtcaata ctactgactc
    73201 tgctgttagg gtaacacata tacctacagg tgaagtagta tcttgtcaag atggaaaatc
    73261 acaattaaaa aataaagagc aagctttaaa aatattaaaa gctagacttt acgataaagc
    73321 attggcagaa caacacaaag atatagcagc agaaagaaaa agccaagtcg gaacaggaga
    73381 caggtcagaa agaataagaa catataattt ccctcaaggt agaataagtg accatagaat
    73441 aaatttaact ttatataagt tagatgcatt cttagatgga gatatagatg aaatgataga
    73501 tgctttaatt actgttgacc aaacagaaaa aatgactgca atataagtaa tgttttaaag
    73561 aagctgtttc ttcctagaaa ttattttcta ttttgaaaca gctattttgc attttaggtc
    73621 atgttatcat attctattgt atataattgt tatatacaag tataggaggg ttatatgata
    73681 ctaaaagtaa caataattgg gcttttggca ggtgttatag ggacaggatt aggaggagta
    73741 atatcagcca tttttaaaag agaggtcgat aaatatctaa gtttttttat gggattatct
    73801 ggtggaataa tgttggctgt agtggtgttt gatttaatga aagaatccat ggacaaaatg
    73861 gggataatca atacagttat atttacgttt gttggagctc tcataactat gtacataaaa
    73921 acaaaattag atgtgtctgg aaatatggca tctggatatc ttatattcat aagtatatta
    73981 ctacataatt taccagaagg actagccatt ggttcttctt ttatgtcaac tgaaagttta
    74041 ggtattacac ttgctatagt tataggtcta cataatatac cagaagggtt agctatggca
    74101 ttaggcttag tttgcaataa aatgaaacta agtaaagtta ttttgtttac tgtaatagct
    74161 ggattaccta tgggtctagg aagtttttta ggtgtttatt ttggaggagt atttacttct
    74221 cttataggag tatttcttgc tacagcagga ggtactatga tgtatgttgt attggaagaa
    74281 atttttccac attcaaaaag tgtgtattgt ataattggtt tcttgttagg tacaatgatt
    74341 gtaaattata tataaaatta aaatgaaagc aggcatacaa aagatgaaaa ctattataag
    74401 taatattgat ataaataata ttgattatga ggaaataaaa atacaagcaa aacttcttag
    74461 agaaggtaaa acagttattt ttccaactga gacagtatat gggttgggtg caaatgcatt
    74521 agatgaaaat gcagtaaaga agatttatga agctaaagga agacctagtg acaatccatt
    74581 gatagtccat atatatgaaa aagaagaagt atatgactta gccaaagata taagtgataa
    74641 agctaaactt gttatagaaa agctttggcc aggacctata acaattatat taaataaaaa
    74701 agatataatt ccatacaaaa ctagtggagg gcttgataca gttgcaataa ggatgccttc
    74761 taatgttatt gccagggcaa taataaaaga agctggtata cctattgcag ctccttctgc
    74821 aaatatctca ggtcgcccat ctccaacaaa agcaaaacat gtatatgaag agatgaatgg
    74881 aagagtggat ggaatagttt taggaggaga cagtaatttt ggattggagt caactgtatt
    74941 ggatttaaca gaagagactc ctatgatact gagaccagga agtataacta aagaagtttt
    75001 agaggaactt cttggagaag taaagcttga cccatcatta agtaaaaaag aagataatca
    75061 aaaagctaaa gctcctggaa tgaaatataa acattattct ccaaatgcag atgtatatat
    75121 aatatctgga aaaagagaaa atgtagcaac aaagattaat gatatgataa aatctaatag
    75181 agacaaaggt ctaaagacag gtgtaatgtg tattagtaga aaccgagagt tttatgatgg
    75241 agaagtaatc gatttaggaa actctcttga agaagttgca agtaatctgt ttgatgctct
    75301 tatagaaatg gacaaaaagg gtgttgatgt catatattca gaagagttcc ccaagactgg
    75361 agttggacaa gcaattatga atagactact gaagtcagca ggatacaaag tgataaaggc
    75421 ttaagaggga gttgtaaaat atgaatatac ttattgtgtg tacaggtaat acttgtagaa
    75481 gccctatggc tgaggctata ctaaggaaag caattaaaga atctggaaga agtattgaag
    75541 aatattctat atcatcagca ggtatatcta cagcaaatgg aatgggtgct tctgaaaatt
    75601 ctatagaagt actaaaagaa atcggtatag acttatcaaa tcatagaagt aaagtaatta
    75661 ctaaaaaatt aattgatgaa tcagatataa tactaacaat gactaaatct cataaagaaa
    75721 ttttagtaca agcagttcca aaatgcaaag aaaaagtgta tacttttaaa gggtttgcaa
    75781 ataaaaatga ggaagatata tctgacccat ttggtggaaa tttggatatt tatagaagca
    75841 ctatgagaga aataatgtat tctgtcaacg aaatagtaaa aaaaatatga aacggaggat
    75901 aaacaaatga agataggatt aggctgtgac catggaggat ataatttaaa aaaagaaata
    75961 ataagctatt tagaaagtaa aggtatagag tgtgtagatt atggaactaa taatgctaca
    76021 gattctgttg attatcctgt ttatggagaa atagttgcaa attcagttat aaataaagaa
    76081 gtagattatg gaatattatg ttgtggtaca gggataggaa tatctttagc tgctaataag
    76141 gttcctggga taagatgtgc agttgtatca gatgtatttt ctgcaaaaat gtcaaaagca
    76201 cataatgatg caaatatgtt atcattaggc gaaagagttt taggaaaagg tctagcactt
    76261 gagatagttg aagcatggat tagtacggat tttgaaggtg atagacatgc tagaagagta
    76321 aacatgatta aatcaataga agaaaaacat aataaataat aaaaattaca gttttatcag
    76381 gaggaattat caaaatgagc aaagtggtag agacaaacca tccattaata caacataaat
    76441 taactttaat gagagataaa aatactggtt ctaaagactt tagagagctt ttaactgaaa
    76501 ttgcaatgtt aatggggtat gaaataacaa aagatatacc attaaaagat gtagaaatag
    76561 aaactcctat tcaaaaaaca tcatctaaag tagttgcagg taaaaaatta gcaataattc
    76621 caattttaag agcaggtctt ggaatggtag atggattagt gagcttaatg ccagcagcaa
    76681 aagttggaca tgtaggacta tatagagacc cagaaacatt aaaaccagtt gaatattatt
    76741 gcaagcttcc tcaagacata ggagaaagag atataatagt agttgaccct atgcttgcaa
    76801 cagggggttc tgctgtagca gctatagatt tacttaagtc taaaggagct aaaagtataa
    76861 aattagctaa tttagtagct gcaccagaag gtatagcaga agtgcaaaaa tatcatgatg
    76921 atgttgatat atatgttgca tcagttgacg aaagattaaa tgaacatgga tatataattc
    76981 ctggtcttgg tgatgctgga gatagattgt ttggaactaa ataaaaataa ataactataa
    77041 atatttatta gggactttct tatatagtgt atataatttt atgtaagaag gttctttttt
    77101 atatattttt tctcaaaata ggaattattg aattgataaa tttctcgaat tgagaataaa
    77161 aagtttttac caattaaaaa agattgctta ttttacaagg ttttatagaa tagtagtcta
    77221 ttttaatgtg gcatgttagt tgcttacgac taagattata ggtattaagt gtattagtta
    77281 aattgagaat tgaatattaa taatattatt gggagtggta atacatgaag aattgtatag
    77341 tagtaagagg ggctggagat ttagcaacag cagttattca taaattacac aacagtggtt
    77401 ttaaagtagt tgcgttagaa atagaagagc cattagctat aagaaggcaa atttcttttt
    77461 gtgaggctgt ttatgaaaaa aaagtaactg ttgaaggtgt agaatgtata ttttgcaata
    77521 ctgaaaaaga aatagaggaa gttttatctc aacataaagt agccttgatt atagacccaa
    77581 aaggagaaaa attatctaaa ttaaatccaa tcgttttggt tgatggaata ctcgctaaga
    77641 aaaacttagg tacaactaaa gatatggcac cacttacaat agctttaggt cctggatttt
    77701 gtgcaggaga agatgtagat gttgttatag agacaatgag aggtcataat ctaggaagaa
    77761 taataactaa tggtagagca gaaaaaaata caggagtacc aggagcaata aaaggttttt
    77821 ctaaagagag agttatgcat tcacagtatg atggcataat ggaaaatgta tgtaagatag
    77881 gtgatatagt tgaaaaggga gacctacttt gctatattaa taattatgaa aaaaaacatg
    77941 aagttagagc aacaatatct ggagtcctta gaggtttatt aaaggatgga gcaaaggtaa
    78001 acaaaaattt aaaaatacta gacatagacc ctagaaaaga agaagttaag aatgctttta
    78061 caatatcaga taaagctaga tgtatagctg gaggggtttt agaagccata ctaaacaatg
    78121 ggatttatcc ccaaaattaa tttatattag ataaagctat taatatttta ttaagatgat
    78181 ataataaatt taatagatta aagagagcat atgacgggta tttaaaattt aaatggtaaa
    78241 aatgctcttt ttttattgga cattcaatta acatgtgtat ataatataaa aataagtatt
    78301 tatttaggtt gaaatctaat aaatatataa taccagtaca taagcaaaga ggagaaaagt
    78361 aaattatgag accatcatgg gatgaatact tcatggaaat tgcagaagta gtgaaaaagc
    78421 gttcaacttg tattagaaga caagtaggag ctgtaattgt aagagacaaa caaatattaa
    78481 caactggata taatggttct ccgagaaatc ttgaacactg tgaaaatatt ggatgtaaga
    78541 ggcaggaatt aaatattccc tcaggagaaa ggcatgaatt atgcagagca ttacatgctg
    78601 aacaaaatgc gataatacaa gctgctcata atggtattag tgtagatggg gcaactttgt
    78661 atgttactac aagaccttgt gttttgtgtg caaaaatgtg cataaatgca ggtatattga
    78721 aaattgttta tgaaggtgat tatccagatg atatgtctac agaattatta aaagaagcag
    78781 gaatagaact cataaaattt tagtggataa aatttatatg acaataaatg tcaaattatg
    78841 acactgaaat acaatggtat caaatgatta aaagaaagta tttgaaaaat catcagatta
    78901 gtagtaagat atattttata attaaataaa tttatgagat agattaatta catgttattt
    78961 attttataat aatgagggat actatttatg agtaaaagaa atacacatac agaaattgca
    79021 aagttgttta gtttaataag ccaaatagga ttgatgattg taatatcaat attaggatgt
    79081 actttcttag gaaaattttt agatagtaaa ttgaatacta ctccagttct gacaataata
    79141 tttttattgt tgggtgttgg aggtgctttt agtggtgttt ataaaactct aatagtatat
    79201 acacgaagga agtgatatat tggatataaa attacttaac caggtaaggt cagtaacaaa
    79261 aggtatagta atatttgatg tagttttaat tgtgctaatg ttgataacat caacattaag
    79321 taaaccagta ttattaggac ttatatttgg ctctataata gctatgttaa attttagatt
    79381 attggcgata tcactggaaa aatcagtgac atttcctgct gggaaggcac aagcttatgc
    79441 atcagcacaa tatgctgtta gattatttat aatggcagtt gttctaattg catcagctac
    79501 agtaccacat ttaaatataa tcggaacagc attgggatta ttgagcacaa agtttgtcat
    79561 attatcaaaa aactttataa ataaattaaa gaggaaggag gcataagtat gaatcaagcg
    79621 cattattatc tcataggaaa ctttaagatt agtgaaacaa tactagtaag ttggggaata
    79681 atggcctttt tagcgatagc atcttatttt ttgactagaa acttaaaaaa agttccaact
    79741 agtaaagttc aaatattctt agaatttgca gtaggtggtc ttgctaaaat ggttacagat
    79801 gttatgggta aaaatacagt aaaaagaatg ccatatatga taccatacat aggaagcttg
    79861 tttttatttt tcgcatgttc aaatttaagc ccattacttg gattaaggtc accaacaacc
    79921 gacttagaca caactgctgc atgggcaatg attacatttt ttatgattta ttttgcagga
    79981 gttaaattta aggggttatc atactttaaa gaattggctc aaccacttgc cataatgtta
    80041 ccaatcaata ttataggtga gttagctaga ccaatatcat taagtttccg tccatttggg
    80101 aatattttag gtggaacaat aataatgggt ctgttttatc aacttttagg ttttatatct
    80161 agtttaatac caggattatc aataccaatt ggagaaatat taataccagt cccattacac
    80221 ttgtactttg acttatttgc aggattgtta caagcatata tatttataat gttaacaatg
    80281 gtatttatat caagtgcagg agagttagat taagaaatca acttatatta agataaaaat
    80341 aaaataattt aaaaaattaa agttttaagg aggaaataat tatggaaaca gcaatagtag
    80401 cggcagcatc agcaatagga gcagggatag cagttgcaac aggtataggt gcaggtatag
    80461 gtcaaggtat agcagcagct aaagctgcag aagcagtagg aaaccagcca gaagctaaag
    80521 gtgatataac atcaacttta ttactaggag ttgctatagc agagtcttca gcaatatatg
    80581 gtttggttat atcaataata cttctattcg taaatccatt ctttaaatac ttaggaatgt
    80641 agatttagtc cttaaatatt ttgagatagg tttataggta aatcatctca aacttataat
    80701 catgagatga actttatcat ctcgtgatta taagtagtta tgatttatgg aaaggaggat
    80761 aattatggaa aaagcactag taggtataac gtgggaattt gtgttccaaa ttgttaatac
    80821 ttttataata tttttacttc tgagaaagct tttattcaag ccagtattaa atataattga
    80881 atcaagagaa aatgatatta aaagtgattt ggcagaaggc gaaaaagcaa aaaatgaagg
    80941 tttagctctg aaaaaagaat atgagtcaaa aatcaatttt gccaaagatg aaggtcaaga
    81001 aatcataaaa caagcaacta taagagcaga gcagaaatca gatgatatag taaatactgc
    81061 aaagaaagat gctcttgata taaaagaaaa agcaaacaaa gatatagaac aagaaagaca
    81121 aaaggttata aatgaaatca aaaatgatat atctaacata gcactacttg cagcatctaa
    81181 agtcattgaa aaagatttag ataaatctaa acatgaagaa ttgatagaaa actttataaa
    81241 agaggtaggg gaagctaaat gataaatgta atagcaaata gatatgccga agccctattt
    81301 caattaggag aagaagaaaa ttcaactgat gtcttattca aagaactaga aaaagtagta
    81361 gatatgatga ctaaagttag taaagatttc tacaaagttt taaaatcacc attagtttca
    81421 aaatcagaaa agaaaaactt ggtagaaatt atttttagta aggaagtaag ttctaacata
    81481 aaaaactttt taaaagtttt agtagataaa gatagaatat catatttaga agatatcgaa
    81541 ttagcttata aagaattatt aaataagaaa aacaatgtaa ttgatggagt agcaataagt
    81601 gctattccaa tgagtgaaac agatattaaa gaacttgaag tcaaactttc aaataaatac
    81661 aacaaaaatg ttactataga aaatgttgtt gacaagacta tactaggggg agttctagtt
    81721 agaattggaa atgaacaaat agatggcact gtgaaaactc gtcttgataa gatgaaagaa
    81781 aagctatctg aagtaatatc ttaagaatgg cggtgaaccc atgaacttaa aacctgaaga
    81841 aataagttct ataattaaac agcaaataaa aaattatgag aataaagttg agttgacaga
    81901 tacaggtagt gttttaacag ttggggatgg tatagcgagt gtatatggat tagaaaaagc
    81961 tatgtccggt gagttgctag agttcccagg tgaaatatat ggtatggcac ttaacttgga
    82021 agaagaagta gttggagctg ttatccttgg agatgacagt gaaataaaag aaggcgatat
    82081 agttaagaga actggaagaa tagttgaagt tccagttgga gaagctttaa taggtagagt
    82141 tgtaaactca ctaggtcagc caatagatgg aaaaggacct atagcgtaca caaaaactag
    82201 accagttgaa tctgaggcac ctggtataat agatagaagg tctgtttatg aaccattaca
    82261 aacaggaatc aaatcaatag attcaatgat accaattggt agaggtcaaa gagagttaat
    82321 aataggtgac agacaaactg gtaaaacatc tatagttatt gacactatac taaatcaaaa
    82381 aggaaaagat gttatctgta tatatgtagc aattggacaa aaacgttcta ctatagctca
    82441 attagttagc tctttagaaa aaggtggagc tttggattat acaatagtag tttcagcaac
    82501 agcatctgaa tcagcaccac ttcaatatat agcaccatat gctggagcag ctatgggtga
    82561 agaatttatg tacaatggga aacatgtact tatagtgtat gatgatttaa gtaaacaagc
    82621 tgttgcatat agagaaatgt cattgttact tagaagacca ccaggacgtg aggcatatcc
    82681 tggagatgta ttctatttac attcaagatt acttgaaaga gcagctaagt tatctgatga
    82741 attgggtgga ggttcaatga ctgccttgcc tataatagaa actcaagctg gtgacgtttc
    82801 tgcatatata ccaacaaatg ttatatctat aacagatggt caaatatact tacaaccaga
    82861 gttattctat tcaggtgtaa gaccagcagt tgaccctggt atatcagtat caagggttgg
    82921 tggttctgcg caaattaaag caatgaaaaa agttgcagga acattaaaac ttgcatattc
    82981 acaatataga gaacttgcag cattctcaca gtttggttct gacttagatg aagatactaa
    83041 aaagagactt gctcaaggtg aaagaatcgt tgagatatta aaacaaggtg agcatcaacc
    83101 aataaaagtt gaaaatcaag ttatgataat atatgctgtt ataaataatc atttagagga
    83161 tattccgata gataatatag ctagatttga atcagaattg tatgcatttg tagataataa
    83221 ttatccggaa atatcaagaa aaatattagg tggagaagac ttcactcatg atttaacaga
    83281 tgcaataaat gaatttaaag aaaagtttgt tgttgaagta taatcctttt taaaaaagga
    83341 ggtaaattaa ttggcaggag ctggaatcaa agcaatcaaa acacgtatgg gaactgttga
    83401 aagtacaaag caaataacta aagcaatgga attagttgca tcttctaagc ttagaaaagc
    83461 aaaagaaaag gctgaagatt caagagaata ttttaatact ttatacaata cagtaaaaga
    83521 tattgcccaa acaacacgtg gaattagaaa tgaattttta aaagaaagag aagtaaaaaa
    83581 taaatgctat gtagtagtag ctggagacag aggacttgca ggtggataca attctaatgt
    83641 attaaaggaa tctgtctctc atatgaaagg taaaaaggaa accgtgatta ctgttggaaa
    83701 gaaagcacat gaattttttt ctaaaagaaa ctacaatata gcaaaagata taaatagtgt
    83761 tgaagcttgt ggatatgaag atgcgacaga aatttcacaa actattattg acctgtataa
    83821 aaaaggtgaa gtagatgaag tttatattgc ttatacaaaa tttaaatctg ctttatcaca
    83881 agaagttgaa attttgaaat tgcttccatt agtctttgaa aaagatacag acgaacaagg
    83941 aatggcagta aaagaagaaa aacaaaatag atcaaaagta caatatatac catcagcaga
    84001 agcagtttta agttatattg tacctcagtt tatatcaggt acagtatatg gtggaatttt
    84061 ggaatctttt gcatcagagc aaggtgctag aagaactgca atggaatcag ccacagacaa
    84121 tgcgaatgaa atgctatcta atttagagtt aagttataac agagcaagac agtcagctgt
    84181 aactcaagaa ataacagaga tagttggtgg agttgaagct ctaaaatagg gaggttagga
    84241 aatggcaaat gtaggtaaag tagtacagat tgtaggagct gtactagatg ttaagtttga
    84301 tagtgaacaa agcctaccta acttattaaa tgcgttagta ataaagttag gagataaaga
    84361 aatagttgca gaagttgctc aacatatagg tgatgatact gtaagatgta tagctatgag
    84421 tgcaacagac ggacttgtaa gaggtatgga agttgtagat acaggagggc caataagtgt
    84481 tcctgttgga gatgaaactt taggtagaat attcaatgtt cttggaaaac cagttgatgg
    84541 gaaaccagct ccaaaatctg cacctaaatt acctatacat agaccagcac cggcgtatga
    84601 tgaactagaa actacagcag agatactaga aactggtatt aaggtagttg acttactagc
    84661 tccatatcta aaaggtggaa aaataggtct atttggagga gcaggagtag gaaagacagt
    84721 tctaatacaa gagcttataa acaatattgc taagcaacat ggtggtattt ctgtattttc
    84781 aggagtagga gaaagaacaa gagaaggtaa cgacctttat ggcgaaatga gtgagtctgg
    84841 agttataaat aaaacagctc tagtatttgg tcaaatgaat gaaccacctg gagcgagaat
    84901 gagagttgct ttaactggac ttacaatggc agaacatttt agagatgagc aaggacaaga
    84961 cgttttactt ttcgttgata atatattccg tttcacacaa gctggttcag aagtttcagc
    85021 acttctagga cgtatgccat cagctgttgg ttatcagcca acattagcta ctgaaatggg
    85081 tgcacttcaa gagagaataa catcaactaa gaaaggttca ataacatctg ttcaagcagt
    85141 atatgtacca gcagatgact taactgaccc agcaccagct acaacattct ctcacttaga
    85201 tgcaaaaaca gttttatcaa gacaaatatc atcactgggt atatatccag cagttgaccc
    85261 tcttgaatct acatcaagga ttcttgaccc tagtatagta ggaaaagaac attatgaagt
    85321 agctagaggt gtacaatcaa tacttcaaag atataaagaa cttcaagata taattgctat
    85381 acttggtatg gatgaattat ctgatgaaga taagttaata gttgcacgtg ctagaaagat
    85441 acaaagattc ttatctcaat cattcacagt tgctgaacaa tttacaggaa atccaggtca
    85501 atatgttcct gttaaagaga ctgtaagagg atttaaagaa attcttgaag ggaaacatga
    85561 tgacttacca gagtcagcat tcttatttgt aggaacaata gaagacgctg ttagaaaagc
    85621 gaagggaagt atgtagtcat ggccagtgaa ttttcattga aagttgtaac tccaagtaat
    85681 actttttatg atggagatgt tgaaatgata gtagttagaa ctacaaaagg agacaaaggg
    85741 gtgttgaaag gtcatatacc atttgtttca ggtatacctg taggaacttt aaagataaaa
    85801 aaagagggaa gttttaaaga ggcgaaaata gcagaaggat tcattaatgt aactcaagat
    85861 aaaactgtca tattgacaga atctgctgag tggatttaat aaattaattt agagtataaa
    85921 aagtcatttt gaccaaaaaa acttttgggt aaaatggctt ttttgtgttt tggtgttaat
    85981 aaaataacga taaaattgta aatttttagt gataataaat tcacaaaatg tttaaattta
    86041 ctgccaaatt atgttgtaat taataagata aagaagattt agatagcttt tatgtaagtg
    86101 aaaaagtctt catataagaa atacatataa aatttttata aaatttaaaa aatttgctta
    86161 gttgtgtagt ataataaata atataataga tttgtatata atattcatta caaataattt
    86221 taaaagttac agttttatta taatgattat taaattaaga taagtaacat aaactaaata
    86281 ataatgtgta ttatcgatag taaatttata aattcattat taattattga aagaagtatt
    86341 ataaattttc tggaggaaca atgaatatat ttgatattgg cgtagatata attgaaattg
    86401 atagaataag aaaggctgta gacaaaaata ataggttttt ggagaagata tttacagata
    86461 gagaaataga gtattttaat tctaagaatt ttaaagcaga aagtatagca ggtaatttcg
    86521 cagccaagga agctataagt aaatctatag gtacaggaat tagagtattt aattttaaag
    86581 atatagaagt tctcagaaat gaaatgggaa aaccaatagt aaaaacttat aataatctag
    86641 caaaaatgtg catagattat aatgttttag aaataaaagt ttcaatatca cattcaaaag
    86701 attatgctat agcaaatgcg ataaccataa ttaaggacta aggagtgatt acattatgat
    86761 ggataaaaca gcaaaagaaa taatgacaac agatgtaata gtagcaaaac aagatgatag
    86821 tatagcagat gtagctaata tgctaattgc agaaaaaata ggaggtctgc cagttgtaga
    86881 ttcagagaat agagttgttg gaataatttc tgaaacagat attcttaaaa aagaaaaata
    86941 tatagaagca cctctctata taaatctatt acaaggattg attttcttag atgacttaaa
    87001 aaaagttgaa aaagatataa aacaagtagc tgcttataag gttggagaac ttatgtctaa
    87061 agatataata aaggttcatg aagatgataa gtttgatgat gtagctaatg taatgattaa
    87121 aaaatcaata aacagagttc ctgtagtaga tgatgacaac aaacttaaag gtataatttg
    87181 tagatatgat ataataaaag ctttatacaa tgaataaact gaagtaggag gtgtgatgtg
    87241 agaaaaaagt ggaccatagt atgtattatg ttcttggcac tggttataat tgtaatagga
    87301 tgccaaaaac gacagtccac aaaagaagaa gtatacaaag attttcaaaa gcagatttct
    87361 gatatgaatt attacagttg taaagctgaa gtagaagtag ttggaaataa aagcccacac
    87421 aattatgttt taattcatac ttataaaaaa accgataact ataaattaga agtaatttcc
    87481 ccaaaacatt taaaagggaa aagtatagaa tatcaaggtg ataaaatatt agttaaaaat
    87541 ccaaagatta gtgatgtagt ggagttacct aatacaggaa aaaataatca atatcttttt
    87601 gtaggagact ttataaaaaa ctatcttcaa aatgaggaga tgaaagtaaa gttatccaaa
    87661 ggacatttgg ttttagagac ttttattcct ggggataata aatattttaa caagcaagta
    87721 ttatatgtaa atgctgacac aaaaaatcct gaaaaaatgg aagtgttaga taaagaggga
    87781 gtgccaagat ttacagtaaa atacaaagat tttgaataca gaaactaagg gggactaaag
    87841 acatgcaaaa aataacagtg cctacatggg cagagataaa tctagataac ttaagattta
    87901 acttaaataa tattaaaaat ttattagaag aagatattaa gatttgtgga gtaataaaag
    87961 ctgatgcata tggacatggt gcagtagaag ttgcaaaatt gctagaaaaa gaaaaagtag
    88021 attacttagc agtagcaaga actgctgaag gaattgaact tagacaaaat ggcataacac
    88081 ttcctatttt gaacttggga tatactccag acgaagcttt tgaagattct ataaaaaata
    88141 aaataactat gacagtttat tctttagaaa cagcacaaaa gataaatgaa attgcaaaat
    88201 ctttaggaga aaaagcctgt gttcatgtta aaatagactc agggatgact agaataggtt
    88261 tccaacctaa tgaggagtca gtacaggaaa taatagaatt aaataaatta gaatatatag
    88321 atttagaagg tatgtttact cattttgcta cagctgatga agtaagtaaa gagtacactt
    88381 ataaacaagc taataattat aaatttatgt ctgataaatt agacgaggct ggtgtaaaaa
    88441 tagctataaa acatgtatca aacagtgcag ctattatgga ttgccctgat ttaagattaa
    88501 atatggtaag agcaggaata atattatatg gtcattatcc atctgatgat gtatttaaag
    88561 atagattaga attaagacca gccatgaaat taaaatcaaa aatcggacat ataaaacaag
    88621 ttgaaccagg tgtaggaata agttatggac taaaatacac aactacaggt aaagaaacaa
    88681 tagctacagt tccaatagga tacgcagatg gatttactag aatccaaaaa aatccaaagg
    88741 ttcttattaa gggagaagtg tttgatgtag ttggtagaat atgtatggat caaataatgg
    88801 ttagaattga caaagatata gacataaaag ttggagatga ggttatacta tttggagaag
    88861 gcgaagttac agctgagcgt atagctaaag acttaggaac tataaactat gaagtgttat
    88921 gtatgatatc aagaagagtt gaccgtgttt atatggaaaa taatgagctt gtacaaataa
    88981 acagttattt gctaaaataa aaccatgata ttataatctg ggaggcgatt ttgtgtacga
    89041 taagagtaaa gaaaaaatag aagttacttt acctgactct ctgatttctg aagttgatag
    89101 tatagttcag atggagaaca gtaacagaga agattttgca aaagctgctt ttcagttcta
    89161 tataactcag aaaaagaaaa ttcatattaa agaatctatg aaaacgggtt atagagaaat
    89221 gggtcaaatt aatctgtcac tagctgaatt aggtatgaca gttgaagaag tatcttctga
    89281 tgataaaaat gaagggaaga ttgcccaagg tgagtactaa ttgtgaaata aagcgtggtg
    89341 atttatatta cgctgattta agtccagttg ttggttcaga gcagggaggc gttagacctg
    89401 ttctgataat acaaaatgat gtaggtaata aatatagtcc tacagttata gtatcagcta
    89461 taacatctca gattaataaa gccaaattac ctactcatgt agagataagt tccaatgaat
    89521 atgggcttaa taaagactca gtaattcttt tagagcaaat tagaactatc gataaaaaga
    89581 gactgaggga aaaaattggt tgtctagatg aaaatatgat gataaaagta gatgatggac
    89641 ttcaaataag tttaggattg tttacttttt aaagagggat ttgtctttta ttagacaatc
    89701 ccttttttct tttaaatatc tcttaaggtt taattttaat gtactatgtt aataaaatta
    89761 aaaataacgc aaaaaaatag cataaaagtg atataataat atggaattga tataaaatta
    89821 cgaactcaag ggaggtaatt gcatgagaga ccataaagga ttaaatgaga ttgcgcgtat
    89881 cataagaaga gatatagttt caatgataca tagagccaaa tctggacatc caggagggtc
    89941 attatcagta gttgaaatac ttactgcgtt atactttgat gaaatgaatg tggattcttc
    90001 aaatcctaaa atggaggata gagatagatt tgtattatca aaaggacatg ctgcaccagc
    90061 attatatgct acattggctg aaaaaggcta ttttgataag gaagaactga atggattaag
    90121 gaagatagga aggatgttac aaggtcatcc agacatgaaa ggcacgccag gtgtggaaat
    90181 atctactggt tctttaggtc aaggtttttc agttgcatgt ggtatggcta tggcatcaaa
    90241 gttggataat gctccgtgga atgtgtatac tttgcttggt gatggtgagg ttcaagaagg
    90301 aattgtttgg gaagctgcta tgagtgctgc acattataaa cttgataatt taattgcttt
    90361 tttagataat aatggacttc aaatagatgg agatatagaa agcgtaatga gtttaggttc
    90421 aatagttgat aaatttaaag cttttggttg gaatgtaatt gagatagatg gacatgattt
    90481 tgaccaaata tttgcggctc ttgatatagc taaatcaaca gttaaaaaac ctacaatgat
    90541 agttgcaaaa actataaaag gcaaaggaat atcttttatg gaaaatcaag caggatggca
    90601 tgggacagct ccaagtgatg aggagctaga aaaagccttg cttgaattag gaggtgctga
    90661 caatgagtaa aatggcgacg agagaagcat atggtaaagc attagtaaaa ttaggtcaaa
    90721 taaatgacaa tgttgtagta ttagatgcag atttatcaaa gtctacaaaa acacatgatt
    90781 tttacaagtc atttccagat agatttttta atatgggtat agctgaacaa aatttaatag
    90841 gcgctgcttg tggattatca actgctggta aaataccttt tgcaagtact tttgctatgt
    90901 ttgctacggg aagggctttt gagattataa gaaattcagt ttgttatcca aagctaaatg
    90961 taaaaatatg tgctactcat gcaggtctta ctgttggaga ggatggagca tctcatgaaa
    91021 gtgtggaaga tattgctata atgagagcta taccaaatat gacagttctt gttccagctg
    91081 atggagttga aacagaaaaa attatttttg aaatagctaa gtataatgga cctgtttatg
    91141 ttagattagg gagaagttca gtaccagttt tatttgatga agattataaa tttgaaatag
    91201 gaaaaggtac agtcttaaga gaaggaaagg atgtatcaat tatagcttgt ggaattatgg
    91261 taaatgaagc tctattagca caagaaaagt tgcaagaaga aggtataagt gctagagtta
    91321 taaacatgtc ctcgataaaa cctatagaca aagatttaat attagaatca gcaaaagaaa
    91381 cgaatgctat tgtaactgta gaagaacata gcataattgg gggattaggt tctgctgtaa
    91441 gtgaggtagt aggagagtct tgtccaacca ttgtaaagaa agttggaatt aaagatacat
    91501 ttggagaatc tggtgcccca aatgaattgt taaaaaaata tgaattaact tgtgatgaca
    91561 tagtaaagac tgttaaagaa gctattattg caaaaagaat gtaagagata taaattattc
    91621 atgtttgtta ataatataat atatttaaaa gagaggtata aagtgttata ttaatttata
    91681 tctctctttt ttttatatga tatcaatata tcaaaaatat aataaaatat tcaaattttt
    91741 acaaaaatag agaaaatatt caaatatata ttgactattc agaaaaatat gactaatata
    91801 taatttatag agaaattaat tttatatata atgactactt agataaaata atctaaaaaa
    91861 attatgaaag gaggactagg gtataaaatt agattataag ttttaagtta ttatactaaa
    91921 aagctataaa acagttatca tgtattttat gttaaaggaa attgtaggta gtttatcgaa
    91981 ttgtttaagc agaagaaaaa atttcacatg gggaggtaac tgagatatgt cagaaaaagt
    92041 aaatgttaaa acagtcatca gtttcgcagg tgcgtatgta gcaacagtaa tcggttctgg
    92101 atttgcaaca ggacaggaaa taatgcaatt cttctctttt tatggttttg caggtattat
    92161 tggtgggata atttcaatgg tattattctc atggatgggt gcttcagtta tgtcaaaagg
    92221 taaagagctt caacttaaag aacctatcaa aatttatcgt gtttattgtg gtaagtattt
    92281 aggaatattc tttgaatggt ttggaccttt attcttattt ggtgttttcg tagtaatgat
    92341 ttcaggagca ggagcaactt taactgaata ctatggatta aatccatttg taggtagagt
    92401 aggtatggca gtagtagcat tattaactgt ttcactaggt cttgataaat tatcaaagat
    92461 actaggtgga atagggccta taataataat ctttacactt ttagttggtg gtataagttt
    92521 agctaaaaac ataggtaata taggagaagc tgcacaagtt cttagcactg taaagatagc
    92581 taaaccagtt ccaaatgcct atctatctgg tgtaatatat actacttata acacaattgt
    92641 tgttatggca ttcttaactg gattaggagc aagtgctgct aacaaaaaag aagctatttg
    92701 tggtggtata ttaggtggag tagcacttat ggctgcagct ataatgatgc acttagctat
    92761 tctttctgat ataggaaact tatattcaaa agcaatacca tcattattct tagcagataa
    92821 gatttcacca gtaattggag ttttattctc aataattctt atattaggta tatatacaac
    92881 agctgtacct ttattatggt cagtaactaa tagatttgta gatgataaac atcctaagtt
    92941 taaattaata actttaatag cagctatatt aggtcttata ggtggcttcc taccatttga
    93001 taagctggtt ggtattttat atccatatac tggatatatg ggcgtcataa tactggtttg
    93061 tgttctttat agacagatta caaaaacatc tggatatcaa gaaggaatca gtgacaaata
    93121 agtatttttt aatattgtaa actcaagagc tatatgaaaa caatgaaaat gttttcatat
    93181 agctcttttt attttttagc tcgtttatta tgaaatagaa aaaacatgtt ttttagttac
    93241 attacatata tttataatta tgtataaata tatactaatc aataatttag agtctaagat
    93301 aagtttataa atcatatatt tagaatatat gggaggagtg ataagattga atgtaaagtt
    93361 taatattaaa ggtataattt atggagttat agctcttgta ttcgttatag ggggatttat
    93421 attcatacca agtatgtttg tagagaaatc taaacccata gattatacag tattacaaag
    93481 aaattcaata ccagaaaaga tattagatgt gatggataag tatacaaatg aagaaagagc
    93541 attagcggct aaaatcgata acaaaatata cattatagtg actagaggaa ataataaata
    93601 tggtatagaa atggacaaaa tagaaagtgt ggttgaggaa ggaaaggatg ttttgagagt
    93661 caagataaag tataaagata aggaagattc ttttccatac atagttgttg aaacaaatat
    93721 gagtgaactt ccagatagaa tagaattaaa tgcgacgaaa taagaaggta ttttataatt
    93781 aaataactgc atattgtaca ataaagtcat ggtttttatt aatgtaagta aattgtgtat
    93841 ggttcttatt gttgtaaaag ccatgactta aaatgcttat aaagtaagat attaacagta
    93901 gtatttatta ctacattaaa tggggtctgg aaatacttaa tattctaact atttggagtg
    93961 ataattctag tttcagtaac tatgtagtct aattgtgcat catgagtttc ttttggaata
    94021 gaatcgaata tctggaagtc aaatgctatg ccgatagtta tagcatcttt tcttaagttt
    94081 tctaaaaatc tatcataaaa tcctccacca tatcctaatc tatagcaatg tatatcatat
    94141 gctacagctg gtacaattac aacatctaag gccttaatat caattgtaga tgatttttcg
    94201 ttaggttctc ttattccata tgctccaatt ctcaatccct cttttaaatc tgttatttga
    94261 gtagggatta atgtatgatt ttcttttatt gtgatgggac ttgatactat tttctttaga
    94321 gacaaaagtt ttttgattaa attatctgtt tgaacttcat tgttaaaatt taaataaagc
    94381 attatattag ttgcatttct tatatcttcc atttgaagta atttttcagt tattaaattt
    94441 gaattactaa gtacaaagtt tgcactctta ttttttcttg attcaataac tttttttcta
    94501 aattcttttt tcataaaata attcctccct taatatgtta taatgtgtac agcaattgta
    94561 tttaatataa attttagtat aatttattgt aataaagcaa tatatttggg taaatgtaat
    94621 aaaaataaca gctagtcata taataataat agtttatgta aaaggagatg tatcttgtga
    94681 tttcaaagaa gaaagctatt tttttagggg tgattttagt aattataaca gctatggtta
    94741 catcagcatt tcagttgaca ttggggaata aagttgtaat atcgaaagaa ctctatgaag
    94801 actataaaaa atatgataag ttgttaggac tagaatctat tataaaacaa gatttttata
    94861 aaaaagtatc agatgctgat ttggtaaatg gagcagcaaa aggtctattt ctaggaacaa
    94921 atgataagta ttctggttat tatactaaag atgaaatgga gaatctaatt aatgatagtg
    94981 aaggttctta tgttggtgta ggtatgtata taggggcatc aaaagatggt ggcttagtag
    95041 tagttcccat gaaagattct ccagcagaga aagcaggtgt aaaatcaggg gataaattag
    95101 taaaagtcaa tggaaaatct gtctcatata aaaattcaga tgaagctgtt cgtatgatga
    95161 agggtaaaaa aggtaaaaca gttgaactga ctatattaag agaagataaa caattgaact
    95221 ttaaagtaaa aacagaccag ataattgaga agagtataga aagtaaagta attgataatg
    95281 atttaggata tatagaaatt acccaattta tatcaagtac atatactgac tttgataaag
    95341 ctttaaaaga attaaaagca aaaaatatca agggattagt aatagacctt agaaataatc
    95401 ctggtggaat gctagatata tgtaaagaag ttgctgatga gttaattggt gaaggaacca
    95461 tagtatatac aaaagataat aagggaaata ctgagtactt gaaatctgat aaagaaaaat
    95521 tgggacttcc aatagtagtg ttaactaatg gagaaagtgc ttctgctgct gaaatattaa
    95581 cagctgcaat cgttgataat aaagaaggta tttctgtagg gactacaact tttggtaaag
    95641 ggttggtaca atcagttgta agattgaagg atggaacagg atacaagcta actactgctc
    95701 aatattttac acctaatgga gattatatca atgaaaaagg tataaagcct actattgaag
    95761 aaaaagatga aaataaacag ttagatgtag caactaagtg gcttagagaa cagattgata
    95821 aataggattt aatttttata aacttatact ataaaataaa gaacattata aaagagatgt
    95881 ctcaaaatga actttttagt tcatgaggga gtctggaaat atttatgtgt attctttaaa
    95941 taaaaattta ttttttaagt gataattaaa tttttacaga cagggctatg gttttaaaaa
    96001 tcatagcctt attttgatat tttttaaaaa cacattgcaa cccagttgtt ccaaatatta
    96061 tatcatttac ttttaaaata tcgcaaactg catattatat attcattata atataattta
    96121 tctaactaga acctcagttt actaattaaa ttagatgcat agaataactt ttttaaacat
    96181 tgaaaataaa ttaaactcta aacacattta aatataaatt tatatatcat tttgacttgg
    96241 ttaaacaatt tcatacttat cgatataaaa ataggttata atataaatgt tcattatctt
    96301 ataacctatt ttatataatt tattcctaaa acatgtgaat gttttttatg atagtttgaa
    96361 gaaattataa aatcacttta taattgaata ttatatataa attaatttaa atatagaaag
    96421 gaaaatatat gtacaacaat atcaaaaata ttttaaaaga aaatcatata acgtttgaag
    96481 aatatgacca tgaacctatt ttatcatttg aaaaagctaa agaaataaga gaaaaattac
    96541 aatatactgg agtagaaagt aaaagtttat ttataaaaga taggtctgga aattactata
    96601 tatttgtaac cacagaagga aaaaaattag atccaaaaac tataaaaaat gttttaggtg
    96661 gaaaagtatc tatatgttca aaagaagaat taacacaaaa aacacaatgt ttgcctggat
    96721 gtgtatctcc ttttggatat gagaaaaata tctctcttgt aatagatcaa gatatattta
    96781 accatgataa aataatcttt tcaccaggga taccagaaaa gacatttatt attacagcta
    96841 gtggatttaa aaaagtaata aataatataa acaatacaac ttataaatat atatattaat
    96901 gaattttaat cataattgta aattagagaa aataacatta gaaatcatgc ttaactatag
    96961 tgtaaataaa ttatattcaa cacaaaagat tgatactatt attacaatag ttactgttaa
    97021 gctcaaattc aatgtattat gagttattat ttttaaattt taattacaaa agcagggtag
    97081 ttttaactac tctgctttat atttaacata aaatatataa aatcaacaaa atgattttag
    97141 tctatctatt agatattctt cgctctcaat gcttaaaact tttagatata tacaataagt
    97201 gctttcattt gtaaaaattt atatgtttgt tcaagataaa aacttacaaa taataataga
    97261 aaagttactt taaatgtaca tattatcgaa aatattatca caaaaatact tataatatat
    97321 atttgtttaa aataacctct atcgcaatag tttattaacg atatggaaat aaaagtgtta
    97381 aatcagattt tggagaaata actttaaata tttccagact ctttttagac agcctccata
    97441 accttatatt gaacctattt attaactttg tacttacaga taccatttat ataagtttcg
    97501 tgtatattaa agtcattatc tgttactata aagtctgcat ccataccttg atatatagag
    97561 ccacagacat tatcaatatt acaacttaaa gcagggacat atgtagccat ttttattgca
    97621 tcttctaaag ttgatatgtt ccaatcaact atatttctca cagccttgtc catagttaat
    97681 acacttccag ctaaactccc actatttaat cttgcaacac tattttttac atttacatta
    97741 aacttaccaa gagtatattt tccatcctcc atagcaccag ctctcataca atctgtaatt
    97801 aaagctatgt tattactaga cttagcatcc ataattattt taacagctat tgggcttaca
    97861 tgatgaccat cacaaattaa ttcagcataa gtatctttta gtaccatagc agccccaacc
    97921 attccaggtt ctctatgatt taaaggactc atcccattat atgtatgtac aaacacttta
    97981 gcacctgaat taacgacttg tttaacttgc tcaaatgtag ctgaactatg accaagagaa
    98041 actgatatat tatttttagt tgcatatctt gttaattcta ttgaaccttt acgttctgga
    98101 gcaattgcta tttttcttat taaatttttc gatttttttt gccataattt taatatattg
    98161 atgtcagggt ctttaaaata tttttcattt tgagcgccct tatatttttc tgtaaaaaat
    98221 ggaccttcta aataaatccc ttgtattttt gcaccctcaa ctcgattgaa gctattgctt
    98281 atattttcta cagaatcact tagtgtatct acagaatcag ttaaagttgt aggtaggaaa
    98341 gatgttactc catattttaa taagcctttt gaaattgtgt ttattgcttc aaatgtattg
    98401 tccatgacat ctgcacctaa aagaccgtga atgtgagtat caactaagcc aggagcaata
    98461 tatttacctg aaaaatctat aacattatca gtaatattag gtctttcttg ttgaaattca
    98521 ccgaatttgc cattaattat actaaggtaa cctttttctt tgattccatg tttcataaaa
    98581 aatttatctg cataaataaa acttttcaaa ataacctcct tataattata ctatcattgt
    98641 ggcattgacg cttataatat cattctgttt tcttgaaagt tatttaactt actatcttac
    98701 atgtcttact ctatatacaa atttatcact tctagcgaca ctcaaagtaa attcaataac
    98761 tatattgtca tcattatatg tggtacgaag taatttcaga caaggtgaat ctcctggtac
    98821 ttccaataac ttagcttcct tatcagagat tattccagct gaaaattctt catcagcaac
    98881 tttaataatc tcgccataat cttctctaaa tatttcatat aaaggttttt gttcgatttt
    98941 ttcttttgtc aatcctataa attctttcat aggaagatat gttctttcaa gcatcatagg
    99001 aaggtcatca gcaagtctta aacgcattat ttttatcatt ttttcaccag tagttatacc
    99061 taatttttca gagaaatact ttgtactttc tactacctca aatgataata cctttgtacc
    99121 tggctttttt ccttgtgttc tcatataatc tgtaaaacta taactttcca ttaagttttg
    99181 agaattttga cttagtgcag caacaaaagt tccttttcca tgtcttttgt atatatatcc
    99241 catatgctct aactcagcca tagctagtct aactgtggtt ctacttactc catattcatc
    99301 acaaattttt ctttcggaaa gcattctatc gtttggttcc atctcatttt caatcttagt
    99361 tcttaatatc tcaacaagct ggtcatatat tggtctttta tcatttcttt ttatcataaa
    99421 aatatagtcc tttctaagtg gttattacca caatttgatt atagaatata gaattattta
    99481 tgtcaatgaa taaagtttaa tcaaaattca ataagtaagg ttattaattt attataaaat
    99541 tatggtacat tgacaaaaca agtaaaataa tttatattca aattggtaat aaccactttg
    99601 ggtatattat agatgaggta ttttttattt tacagattaa tttattgttt agaaaagtaa
    99661 aaattaataa tgaggagaat ctagtatgat tacagtaata acattcaacc catctataga
    99721 tagaatgtat agagtgaata atataaacat aggtgaggtg caaagggtag taagtaagaa
    99781 tgcaactgct ggaggtaaag gattaaacgt agctaaggta tgtaaaattt taaaagaaaa
    99841 tcctttagct atgggatttc taggcggatt taatggagaa tttataaaaa atgaacttag
    99901 aaaactagat atacaaaata aatttacaaa aatagagcag gaaactagaa attgcttaaa
    99961 cataattgag gacaataaag ttagtacaga atttttagaa aaaggaccaa tagtagaaaa
   100021 aagcaattta gagagatttg aaaatgatat agaggaagta ctaaaaaata ctaaaatact
   100081 ggtagcttct ggtagttatt gtgagaatat gccgatagat tattatgaaa agataggaaa
   100141 tatatgtaga gcaaataata taaagtttat attagataca tcaggagaag cattaaaaat
   100201 agctttaaaa tcaaaaccat atttaataaa accaaatata gatgaaataa gacatttatt
   100261 aggaataaat atagaatcaa gagaggaaat tatcttgtca ggaaaaaaac ttattgaaat
   100321 gggtgcagag aatgtatgta tatctttagg aaaagatggt atggtgtatt taaacgaaga
   100381 taatgtatat gatgtaaaag taccagttgt aaagtgtata aatactgtag gtagtggaga
   100441 tagcacagtg gctggattta gtgtaggcat tttaaggggt tataaaatag aaaatttact
   100501 taaatttgca aatgcttgtg gtataagtaa tgctttaaat atggaaactg gatttgtaga
   100561 tttgggagaa attgataaat atcaagattt agttgaagta aaaaagttaa gttaaataca
   100621 tttaatggga atataataaa tttaatgttg ttgtaataga ttttaatata aaagatatag
   100681 tcttatataa aaataggtta gaaaaattca tttttaacct atttttataa taaatatcta
   100741 ttttactgaa tttataattt tctctagtaa tctttgagcc ttgatacact cttctccact
   100801 gatagctggt tttatattat tttctataca atcaataaaa tgatttgata tatcctcaaa
   100861 acccttttgt tttaatatat ttacccatgc accactttgc tttaaagtta ggtttccacc
   100921 ttcttctatt tccagtacat taagattctt aactctttga atcttaccct ttgaaagaat
   100981 ttcaacttgt tctaactttg ttccagaatc tctatgcata gaggtgttta tagagaaatt
   101041 tttacattta agtttatgac ttacaaatat aagattctta ttgtctgtta aaaataaatc
   101101 ttctccacta atttcaacat cttcatttgc taaccataaa gcagtgtcaa taacatgtat
   101161 atagtcatct ataagagtac tgtcgaattt aacatttctt aaggaattta atccgtgttt
   101221 acatatattg atagatacga tttctgtagc attattttta atttctttgt acataggaca
   101281 gaatctacgg ttgaatccaa ccattaaatt taaatttttt ttcgtactta actcgataag
   101341 ttcttctcct tgacttactg ttgaagcaag aggtttgtct acatatacat gaacacctaa
   101401 atttaataat atttttataa tttcgtagtg tgtttctgta gagctatgta gaaaaataca
   101461 atcacatttt ttagctagag attcaataga atcgaatggc atgattctat aatcactaca
   101521 gattttttct cttttaactt tatttggagt aaaagctcct acaaactcaa atctctcaga
   101581 cttagttaat ataggtaaat atgccttttg agctatggag ccaagaccta tcattcccat
   101641 ttttatattt ttcataatac tttctcctaa ggtttttata tttacagaat tgattataat
   101701 tcagacacat aaatttgtaa actttgtatc aaaaaataaa tttaaagctt atataagtaa
   101761 attagcgaaa taagaaatat tgataaagta attttttagg atatctataa aattgattga
   101821 tataaatatt ttatgtattg acaaaaaatt caaattaatt tatatttgga ttagtggtaa
   101881 ttaccacttt ggtctgaaca agtttttatc gtaaaataaa aatactaaag tatatagagt
   101941 atgattttat taaattttta aagataaact ataaaattaa ttaaaatcta tagcgtatat
   102001 tttatagtga gtttaagtag tactaaaaaa tctaagcaaa aaattataaa agagtatatt
   102061 tttttatagt ttaaagtggt tataacctca ttaccaaatg taaacgttac aagtatgaaa
   102121 ggagaatgaa aatgtttaaa ttagaagaac aaaaactaaa agttttaggt gcaataataa
   102181 caactaatga aataaaacaa cagcctgaat tatggttaga aacttatgaa atatataaat
   102241 ctaacaaaga aaaattaagt agattcatag atacaataag taataatcat gggcagttta
   102301 gagttatatt tacaggtgct ggaacttcag cttacatagg aaattcaata cttccttacc
   102361 ttaaaaataa aaatgacata agaaaataca tatttgaagc aatacctact acggatatag
   102421 tttcaaaccc atatgattac ttaaaaaaag atataccaac attattaatt tcatttgcaa
   102481 gaagtggaaa tagtcctgaa agtttggctg ctttaaattt agggaataag attgtagata
   102541 atttttatca tttagctata acttgtaatc cagaaggaga actggctaag atgactaaaa
   102601 acgacgaaaa taattacttg ttattaatgc catcaaaatc aaatgatgaa ggctttgcca
   102661 tgacaggaag tttttcgtgt atgatgttat ctgctatgtt aatatttgac agtttagaag
   102721 atgatgtaga aaagtcatat ataaatgcaa taattgaaat gggaagaaat gttatagata
   102781 gaaaagatga aatacatgag ttaataaata aagattttga tagagttgta tatttaggtt
   102841 caggaggatt aggtggtttg acacaagaag cacaactaaa acttttagaa cttacagcag
   102901 gaaaaatatc tacggtgtat gattctccta tggggtttag acacggacca aaatcattta
   102961 ttgatgaaaa tacacttgta tttgaatttg tatctaactg tttatataca agaaaatatg
   103021 atttagatgt tttagaggag ataaaaaggg ataaaattgc taaattcact tgtgcagtgt
   103081 cagtagaaaa tgaaaataac ttctcaggaa caaagtttga gtttaaagaa aagtataata
   103141 aattaccaga tgtgtatctt gcaatgccat acatattgtt tgcacaaact atagcattgt
   103201 ttgtatcggt aaaggttgga aataagccag atacgccatc agctacagga acagtaaatc
   103261 gagtagtaaa aggtgtaaca atatatgaat attaaaagat aagattaaaa tattataact
   103321 aaataatttg ggagggtatc aatgtggcat tagtaacaac aacatcaatg cttaaaaagg
   103381 cacaagatga agggtatgcg gtaggagcat ttaatgtaga aaatatggaa atggtaattg
   103441 ctgttataga agctgctgag gagttaaatt ctccagtaat attacaaact actccatcta
   103501 ctgtaaaata tgcaggtctt gattattatc tagcaaatgc aaaggttgct gcagaaagag
   103561 taaatatacc tgtagcaatg catctggacc atggttcaag ttttgacctt gcaatgaaag
   103621 ctttaagaag tggatataca tcaataatga tagatggttc tcatgaaagc tttgaaaata
   103681 atatatctat atctaaatca gtagtaaaag catgtagtcc ttctcttata ccagtggaag
   103741 cagaacttgg gaaagttggt ggaaaagaag atgatttaga tggcgggaat agtaatgatt
   103801 atacaaatcc aaaagaggca aaagagtttg tcgatagaac aggaatatct tcattggcta
   103861 ttgctatagg tactgcacat ggattgtata agggtgaacc taaaatagat ttagataggt
   103921 tatcagaaat taaaaatgta gtttcaatac ctttagtatt gcatggaggt tcgggaatac
   103981 atgatgatat tataaaagaa gctataaaaa gaggtattgc aaaagttaac tatgcaactg
   104041 aattaagaat tgcatatagt aaaggggtta aaaaagtttt agatgaagat tctgaggtta
   104101 tagaccctaa aaagtatgga ttagcagggc ttcaatcagt aaaggatttt gtgaaagaaa
   104161 agattaaagt gtgtgggtct gtaaatagag tataaaaata aaatatccta aatttatttt
   104221 agataagttt aggatatttg ttata
//
LOCUS       DAEORM030000007       101988 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.007, whole genome shotgun sequence.
ACCESSION   DAEORM030000007 DAEORM030000000
VERSION     DAEORM030000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 101988)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 101988)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 101988)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..101988
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.007"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            complement(121..894)
                     /locus_tag="KRH23_000712"
     CDS             complement(121..894)
                     /locus_tag="KRH23_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SigB/SigF/SigG family RNA polymerase sigma
                     factor"
                     /protein_id="HHS5224008.1"
                     /translation="MKNVANATHYLNMDTKELFNLYNKNKNVDIRNILIERHLYLARL
                     LAKKYINKGVDFEDIYQVASLALIYAIDRYDVEKGFEFSSFATPTIVGEIKKYFRDKV
                     WTLRVPRRIQELSKKISDAKIKLEQENKKHPKVKDIADYIGVSEEDVLEAMEASYGYQ
                     PMSLDSSSNDDSEDKDITLIDKIGKEEGNFGSIEYEDFINKFIETLNELEVKIFKDRF
                     FFDKTQSSIAKELGISQMTVSRLEKKVVEKLKKEYEKNL"
     gene            complement(894..1301)
                     /locus_tag="KRH23_000713"
     CDS             complement(894..1301)
                     /locus_tag="KRH23_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HHS5224009.1"
                     /translation="MACETIKMEITTNPDYVSIIRLTASGIANKMGFPIDDIEDIKVA
                     VSEACTNAIKHSKDDVFNIVFNILDNAINIEIQDNGKGYDVSSISTPDLENPKESGLG
                     LFIIKTLMDDVDIESEHNQGTKIKMTKYLGVDI"
     gene            complement(1305..1622)
                     /locus_tag="KRH23_000714"
     CDS             complement(1305..1622)
                     /locus_tag="KRH23_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043856 - anti-sigma factor antagonist
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="STAS domain-containing protein"
                     /protein_id="HHS5224010.1"
                     /translation="MSMNIDSNLDSQNKFWNVCLDGELDVSTADKLKEHLHALIEKNM
                     LDVKINLKDLDYIDSTGLGAMIGVLKKLKINEKEIYIVNPKSNVRKIFTITGLDKIFK
                     VEG"
     gene            complement(1634..1894)
                     /locus_tag="KRH23_000715"
     CDS             complement(1634..1894)
                     /locus_tag="KRH23_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HHS5224011.1"
                     /translation="MNAWGWQIGAVLVGSSALIVAIYLAKTLNSINKVVEKAYKIVDY
                     NERHIQDIVENASSISKGIDDIVYVINKILSIGNIFKIIKRK"
     gene            complement(1894..2190)
                     /locus_tag="KRH23_000716"
     CDS             complement(1894..2190)
                     /locus_tag="KRH23_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HHS5224012.1"
                     /translation="MCNKRSCKKGGFLLLGAILGFIFGMFFAPKKGSELRKETKEKFN
                     DVKENPKEVLHETFNDVKERIINLVDDDNNEEDIKISEEDIVISKSFDDEGDVN"
     gene            complement(2259..4685)
                     /gene="gyrA"
                     /locus_tag="KRH23_000717"
     CDS             complement(2259..4685)
                     /gene="gyrA"
                     /locus_tag="KRH23_000717"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006259 - DNA metabolic process [Evidence
                     IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HHS5224013.1"
                     /translation="MEENNKILPIEIAEEMKKSYIDYSMSVIAGRALPDVRDGLKPVH
                     RRILYSMSELNLTPDKPYRKSARIVGDVLGKYHPHGDTAVYYAMVRMAQDFSTRALLV
                     DGHGNFGSVDGDSPAAMRYTEAKMSKLSLELLRDIEKETVDFKPNFDESLKEPSVLPA
                     RYPNLLVNGSNGIAVGMATSIPPHNLAEVIDATVYLIDNPECSVDDLIKFVQGPDFPT
                     AAIIMGKESIAEAYRTGRGKVKVRSRAFIEELPKGKQQIIVTEIPYQVNKAKLVERIA
                     ELVKEKRIEGISDLRDESNRNGMRIVIELKRDANANIVLNNLYKHSQMEDTFSIIMLA
                     LVDGQPRVLNLKQILYHYIKHQEDVVTRRTKFELNKAEARAHILEGLKIALDNIDAVI
                     SLIRASKTGQEAKLGLIEKFKLTEIQAQAILDMRLQRLTGLERDKIEAEYEDLIKKIN
                     RLKEILADERLLLNVIKDEITIIKENYSDERRTEIRHAEGEIDMRDLISDEEIAITLT
                     HFGYIKRLPSDTYKSQKRGGRGISALTTREEDFVRHLVTTTTHSRLLFFTNKGRVFKL
                     NAYEIPEGKRQAKGTAIVNLLQLSADEKIATLIPIDGNDENEYLLLATKKGIVKKTKR
                     EEFKNINKSGLIAIGLRDDDELIGVELTDGKQEVLLVTKEGMSIRFDENDIRYMGRTA
                     MGVKGITLSKEDFVVSMNLCSKGTDVLVVSKNGFGKRTNIEEYRSQIRAGKGIKTYNI
                     SEKTGTIVGADMVNEDDEIMIINSDGVLIRIRVNEISLFGRVTSGVKLMKTNDEVNVV
                     SIAKINIEEE"
     gene            complement(4705..6606)
                     /gene="gyrB"
                     /locus_tag="KRH23_000718"
     CDS             complement(4705..6606)
                     /gene="gyrB"
                     /locus_tag="KRH23_000718"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HHS5224014.1"
                     /translation="MKQEYGASQIQVLEGLEAVRKRPGMYIGSTSPRGLHHLVYEVVD
                     NSIDEALQGYCSDIYVSINEDGSVLVKDNGRGIPVEIHPKTGKSTLETVLTNLHAGGK
                     FGGGGYKVSGGLHGVGVSVVNALSKWMVAEVYLNGKIYKQTYEKGLPTSKLEVVGESQ
                     DKGTMIQFMPDETIFDEIEFKYETLEYRLRELSFLNKGIKIVFEDKREGQEKRKEFHY
                     TGGLVEYIKYLNKSRTGIHDDIVYIDKKVDDCFVELAMQYTDGYTENIYSFANNINTH
                     EGGSHLSGFKAALTKTVNDYAKRNKFLKENDVNLLGEDIREGLTAVVSVKLPEPQFEG
                     QTKTKLGNSFMRGIVDSVTVDELGSFLEENPSTARIIVDKALRAQRAREAAKKARELT
                     RRKSVLESTSLPGKLADCAEKDPSKSEIFLVEGDSAGGSAKQGRDRNSQAILPLRGKI
                     LNVEKSRLDRILSSDEIKNMITAYGCGIGEDFDIDKARYHKIIIMTDADVDGAHIRTL
                     LLTFFFRYMRPLIDEGYVYAAQPPLYKVTKQKKEHYVYSDKELNILLDEIGRNGVELQ
                     RYKGLGEMNAEQLWETTMNPETRTLLQVTVEDAAIADEVFSMLMGDKVAPRKEFIEEN
                     ARFVRNLDI"
     gene            complement(6607..7722)
                     /gene="recF"
                     /locus_tag="KRH23_000719"
     CDS             complement(6607..7722)
                     /gene="recF"
                     /locus_tag="KRH23_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420477.1"
                     /note="All proteins in this family for which functions are
                     known are DNA-binding proteins that assist the
                     filamentation of RecA onto DNA for the initiation of
                     recombination or recombinational repair; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0009432 - SOS response [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HHS5224015.1"
                     /translation="MKLKSLQLVNFRNYKKLHLEFNGKVNLLVGKNGQGKTNIVESIY
                     MLSFGKSFRTNKDKEMVRFNSENLYIGGSFSKYNKYSLIELIIGKDKKGIRINKVPLQ
                     KIQELLGNLNVVIFSPEDLRLVKEGPKERRAFIDKEISQIIPKYYKYLTNYNKTLSQR
                     SRVLKNIHVDEALLDVYDDTLAKYGSYIYILRRDFIKKIANISENMHMNLTNGVERLS
                     IRYKNQINITDEDTIDTVYNKFLAKLSSNRPNDIESKTTRYGIHKDDLNIFINDLDAR
                     LFGSQGQQRTASISLKLSEIELIKNEVEEYPVLILDDVFSELDEARQKLLVNNLSNVQ
                     MFITSAEVSHKKIFDEKNVTIFNIENGDVISIENGGN"
     gene            complement(7739..7945)
                     /gene="yaaA"
                     /locus_tag="KRH23_000720"
     CDS             complement(7739..7945)
                     /gene="yaaA"
                     /locus_tag="KRH23_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HHS5224016.1"
                     /translation="MTEITIESEYIKLDQFLKLAEIASTGGHAKFLIQEGLVTVNDEI
                     ELRRGKKIKSGDIVEIEGTKIKVL"
     gene            complement(8082..9188)
                     /gene="dnaN"
                     /locus_tag="KRH23_000721"
     CDS             complement(8082..9188)
                     /gene="dnaN"
                     /locus_tag="KRH23_000721"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HHS5224017.1"
                     /translation="MKIICNQKILANRIGIAQKAINGKTTIELLKGILISTEEGQLKL
                     TGYDAEIGIETYVQAEIIEKGDVVVDARLFGDIIRKLPDSFVEIETDSENNIYINCVN
                     SRFKIKGYAAKEFPKLPELNEEDLYSIPQEILKNMIKQTVFAISQDQTKPVLMGELLE
                     IVDRNLNLVAIDGYRLAVKSCSVDSLTENIKVIIPGKTLIDVNSLLSGEDNVKVGFNE
                     KNAIFIINDTKIITRLLEGDFIDYKKLLPREHNSRVKLNTKELLNSIERASLLSQSEK
                     NNLIKLSIRDKVMAITSNTEKGNVYEEVEIDLDGDYLDIAFNSRYFIEGLKNIDNEEI
                     FIEFTTNVNPCIIKPTDDVNYIYLLLPVRISSNI"
     gene            complement(9430..10749)
                     /gene="dnaA"
                     /locus_tag="KRH23_000722"
     CDS             complement(9430..10749)
                     /gene="dnaA"
                     /locus_tag="KRH23_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003688 - DNA replication origin binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA];
                     GO_process: GO:0006275 - regulation of DNA replication
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HHS5224018.1"
                     /translation="MDIVSLWDKTLQLIKGDLTSVSFNTFFKNIVPLKIHLNDLILLA
                     PSDFNKDILENRYLHLIEDAISQLSLKKYNIKFVLSEKEVADLNSDSTDLNYRVLYPN
                     LNPKYTFDTFVIGNSNRFAHAACVAVAESPAKAYNPLFLYGGVGLGKTHLMHAIGHHI
                     VSQKKDSKVVYVSSEKFTNELINSIKDDKNEEFRNKYRNVDVLLIDDIQFIAGKERTQ
                     EEFFHTFNTLHEANKQIIISSDRPPKDIPTLEDRLRSRFEMGLITDIQAPDFETRIAI
                     LRKKAQLERIDVPNEVMSYIAKNIKSNIRELEGALTRVVAYSSLSNRVISFDLATEAL
                     KDIITTSKNEEINVLRIKEKVSSVFNLKMEDFNSKKRTRSIAYPRQIAMYLTRELTDL
                     SLPKIGEEFGGRDHTTVIHAHDKVSKDIEESEEIKTKIDKIISDLKG"
     gene            11408..11545
                     /gene="rpmH"
                     /locus_tag="KRH23_000723"
     CDS             11408..11545
                     /gene="rpmH"
                     /locus_tag="KRH23_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HHS5224019.1"
                     /translation="MSKRTYQPKKRQRSKEHGFRKRMKTSNGRNVLKRRRAKGRNRLT
                     H"
     gene            11623..11967
                     /gene="rnpA"
                     /locus_tag="KRH23_000724"
     CDS             11623..11967
                     /gene="rnpA"
                     /locus_tag="KRH23_000724"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0004526 - ribonuclease P activity
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HHS5224020.1"
                     /translation="MDFNRTKGLKKDSDFRKVYKHGKSFANKYLVIYILKNKSDYSRV
                     GISVSKKVGKAITRNRVRRLIKEAYRLNIDEKIKPGYDIVFIARVSSKDATFKDIDKS
                     IKNLVKRTDISI"
     gene            11999..12250
                     /gene="yidD"
                     /locus_tag="KRH23_000725"
     CDS             11999..12250
                     /gene="yidD"
                     /locus_tag="KRH23_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HHS5224021.1"
                     /translation="MNKIIYILKEISKYLSNLCIYLVRFYQKYISPLKGPTCRFYPTC
                     SQYSIEAFKKYGFVKGMYLTIRRLLKCHPFHPGGYDPLK"
     gene            12282..12989
                     /locus_tag="KRH23_000726"
     CDS             12282..12989
                     /locus_tag="KRH23_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YidC/Oxa1 family membrane protein insertase"
                     /protein_id="HHS5224022.1"
                     /translation="MNIIGNFLGLILKVIFEFVNHYGISIILFTILVKIILLPLTIKQ
                     TKSTKAMQDIQPRIKEIQEKYKNKPEKQNEEIVKLYGEAKINPLSGCLPLLIQFPILI
                     GLFSVLREPVAHGVFANKAAFLAADNGFLWIKSLTSPDYVLAVFSGASAYVMQKVMTP
                     KDQLQGSMKVMTYVMAGMSFYWGFIFPAGLTLYWTVSNLFSIAQYYLIMNPLKAKLAA
                     NSKEEKVNEKKPKINKK"
     gene            12958..13587
                     /gene="jag"
                     /locus_tag="KRH23_000727"
     CDS             12958..13587
                     /gene="jag"
                     /locus_tag="KRH23_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding cell elongation regulator Jag/EloR"
                     /protein_id="HHS5224023.1"
                     /translation="MRKSLKLIKSKSKEEAISKAIAELNLKAEDIEVEILENPSKGFL
                     GFIGAKDGTYEIFVIEREVDVAKNFIEVMLKNANVDAKVNVSQKDNLIMVDIEGKEAA
                     SLIGRRGETLDSIQFLTGLALNKINKDSHTRVLVDIENYRSKREESLIRYANKVAREV
                     AKTRKTKKLDYMNPYERRIIHSALQNDKYVITYSEGTDPYRRLVIECKR"
     gene            13699..15078
                     /gene="mnmE"
                     /locus_tag="KRH23_000728"
     CDS             13699..15078
                     /gene="mnmE"
                     /locus_tag="KRH23_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HHS5224024.1"
                     /translation="MFIDDTIAAIATAPGEGGIGILRISGEKALKVAEEIFKSMSGKS
                     IEEYNKRTLIYGNIVDNENIIDEVLLAYMKGPNSYTGEDVIEINCHGGFISVKKILEL
                     ILSKDVRLAEAGEFTKRAFLNGRIDLSQAEAVIDVIKAKTDIAHEVAQNQLEGSLSKK
                     IRELRDKVTEILAHVEVAIDYPEEDIEHITYQTLKEKTDELKKDIKKLYDTAESGKIL
                     REGLKTVIVGKPNVGKSSLLNSILGENRAIVTDIPGTTRDVIEEFVNIKGIPLKIVDT
                     AGIRDTDDIVEKIGVEKSKESFTSADLIVMVLDASRKLSEEDIEILEKLKDKQTIVLL
                     NKNDLKQEIEEEKILKYVENNSIIKISALQQEGIEELQDKIESMVYKGSIKNNSSLVV
                     TNSRHKDALSKAYKSATDALIALEQSMPFDFVEVDLKNIWDYLGYINGDTVTEDLLDN
                     IFHNFCIGK"
     gene            15173..17068
                     /gene="mnmG"
                     /locus_tag="KRH23_000729"
     CDS             15173..17068
                     /gene="mnmG"
                     /locus_tag="KRH23_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002098 - tRNA wobble uridine modification
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HHS5224025.1"
                     /translation="MIKFEAGKYDVIVVGAGHAGCEAALATARMGYKTLIITMSLDSI
                     ALMPCNPSIGGTGKGQLVKEIDALGGQMGLNIDKTYIQSRMLNTAKGPAVHSLRAQAD
                     KFKYHEEMKKTLEDEPNLDIAMDEVVEILHEGNVVIGVGTKLGCSFKSKAVILATGVY
                     LNSKIYMGEVAFYEGPNALGYAKYLTDSLVELGLRMRRFKTGTPARVHRDSIDFSVMS
                     LQEGDEKVTPFSFMNENIEKKQEPCYLTRTTEETQKVILDNLKRSAMYSGVIESTGPR
                     YCPSIEDKVVRFSDKTSHQLFIEPEGLNTKEMYIQGISTSLPFEVQLDMYKTIKGLEN
                     CKIMRPAYAIEYDCVDPTQLKISLEIKGVENLFSAGQFNGTSGYEEAAAQGLMAGINA
                     VRKIEGKEPFVLDRSEAYIGVLLDDLVTKGTNEPYRMMTSRAEYRLYLRQDNADMRLT
                     QKGYDIGLVKKDRYERFLNKKAAVEKEFERLKNERVTPKEVNSLLEEKGATPIKVGIS
                     LYEFLKRPEVTYELLEELGKGAGEDVSREVKEQCVIITKYEGYIEKQLKQIDQFKKLE
                     NKKLDEKINYSSIEGLRLEARQKLDDIKPISIGQASRISGVSPADISVLLIYLEQIRR
                     TRGGKGE"
     gene            17061..17780
                     /gene="rsmG"
                     /locus_tag="KRH23_000730"
     CDS             17061..17780
                     /gene="rsmG"
                     /locus_tag="KRH23_000730"
                     /EC_number="2.1.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0031167 - rRNA methylation [Evidence IEA];
                     GO_process: GO:0046118 - 7-methylguanosine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HHS5224026.1"
                     /translation="MNNIELLKNGIEGFNIDTNDSMLEKFKIYREILVEWNKKMNLTG
                     IEDEKEVYIKHFLDSISAVKNGYIKNGMSIIDVGTGAGFPGIPLKICLDSLELTLLDS
                     LNKRINFLEEVSRVLELDNITFIHGRAEDFGKNEDYREKYDVATARAVAGLPILMEFC
                     VPFVKVGGYFICLKGPNANLELEESQKAIDVLGLEYIEKIDVELPEVDLNHNILVFKK
                     VMETPVKYPRKAGKPAKNPIK"
     gene            17943..18728
                     /gene="noc"
                     /locus_tag="KRH23_000731"
     CDS             17943..18728
                     /gene="noc"
                     /locus_tag="KRH23_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0032466 - negative regulation of
                     cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid occlusion protein"
                     /protein_id="HHS5224027.1"
                     /translation="MEDKRVMEIPIEDVVPNPYQPRKIFSQVSLEELSNSIKVYGIIQ
                     PITVRAKDGKYELIAGERRLRAAKLAELKTIPAIINNMNDESSAVLALLENLQREDLN
                     FIEEAIGYENLIKEHAFTQQQLAEKLGKNQSTVANKLRILKLPNDIKMKLIENNLTER
                     HARAFLKLPSEDLMQSVLDKVIKNELTVKKTEKLIQDVLEETKVQEEPDKKQNIKGAM
                     SIRIYINTIKQAFDAISNTGIDAKYNEIDKGDYMEVVVKIPKK"
     gene            18863..19636
                     /locus_tag="KRH23_000732"
     CDS             18863..19636
                     /locus_tag="KRH23_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HHS5224028.1"
                     /translation="MGKVIAVFNQKGGVGKTTTNVNLSASLGTLGKKILVLDLDPQGN
                     TTSGYGINKNEVENTIYEIMLDGLHIKEAIISTEFENIDVVPSATELSGAEIELTSKT
                     NREYILKNSIKAVIDEYDYIFLDCPPSLGMLTINCLTAVDSVLIPIQCEYYALEGVSQ
                     LMETIKLVKSRLNADIEIQGVVLSMFDGRANLSIQVVEEVKKYFKGSVYTTLIPRNVR
                     LAEAPSHGKPVIYYDKRCRGSVAYLELAEEFIDLEEEEW"
     gene            19638..20501
                     /locus_tag="KRH23_000733"
     CDS             19638..20501
                     /locus_tag="KRH23_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HHS5224029.1"
                     /translation="MENKSKRSNRLGRGLSALIPEIKGETSEKEIVNIDIDKIYPNEV
                     QPRKQFDEEKIKVLSDSIKNYGVLQPIVVKMDENNKYMIIAGERRFRASKLANKNQIP
                     AIIKDIDMKDIMEIALIENLQREDLNSIEEALAYKSLIEHYNVTQEEISEAVGKSRPH
                     ITNTLRLLNLGQDVIEMIDSGRITAGHGKALLRIADKDLQLQIAKKIEEEELSVREVE
                     NIAKKISENKQEEPKKSKPKDVFILDVEDKLRNIFGTKVNISKGKKKGKIEIEYYNDD
                     DLNSIVSMLLE"
     gene            20534..21676
                     /locus_tag="KRH23_000734"
     CDS             20534..21676
                     /locus_tag="KRH23_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HHS5224030.1"
                     /translation="MIYLDNAATTYPKPERVYNAVLDCMKNYCANPGRAGHKLAMRAA
                     REIYDTRENIAKLFNVSNPMNIVFTSNATDSLNLAIKGVLQEGDHVITTSMEHNSVIR
                     PIKALEKRGIENTVVKCDYEGFLDYEDLEKSIKNNTKLIVTTHASNVCGTLIDIKKVG
                     EIAKKHNILFLVDASQTAGVYDIDVNECNIDMLAMPGHKCLFGPQGTGILYVREGLNL
                     NILKEGGTGSKSEEIVQPELFPDKYESGTHNTPGIAGLNQGILFIFERGINNIRQHEE
                     ELCQYMIDKLEEVPDIKIYGPKDSKKRASVIALNIGDMDSGEVTFLLDSDYNIATRSG
                     IHCSPLAHTTLGTLKQGAVRFSIGYFNTKDEIDKAVEALKKISKNK"
     gene            complement(21809..22384)
                     /locus_tag="KRH23_000735"
     CDS             complement(21809..22384)
                     /locus_tag="KRH23_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GerMN domain-containing protein"
                     /protein_id="HHS5224031.1"
                     /translation="MKNKKIMLVLSILSISIFAVGCTNAQNGSDSSKKETKSNTNVEQ
                     PKEENNTEKEVPNNKTKPTPKEETKTQSATIYSFDVDKTDLIENKVDLNKIDENTLFE
                     ELQKLKVVPESAKLNSFTTKDIDGVKTGILDVSSDFTKSNLGSDAETLMLDSVARTYI
                     KNMNVEQIKITVDGSNYESGHIVLEEGDYLK"
     gene            22644..23936
                     /gene="rstA"
                     /locus_tag="KRH23_000736"
     CDS             22644..23936
                     /gene="rstA"
                     /locus_tag="KRH23_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin production/motility transcriptional
                     repressor RstA"
                     /protein_id="HHS5224032.1"
                     /translation="MEILSLGEKIKKLRKEKNMTLKELAGDRITAAQISHIERDKSHT
                     SYELLEYLGDKLDVSVEYLLETKEMQSKKITDNLILQSEIYIKENELNKAEDQIKEVL
                     DICKRYDLMENYGRCNFLMANINLKKSNYNDAIENFEKALYFFIKNSDSENILKCYLN
                     IGKIYMQEDFYKGAISHFNFAEEILSESKFEDVNIHKELYSKMAYCYIKLDNPNMSLK
                     YIEKINEIDNRNDRKEDVDILVLKANNMLEIGKYEESRDYFKKALKILESEDNKTGLA
                     NVYLTICDVYRKIGETDRVLEYSQKVYDIKKNDEDEYMMSGLFKIIEAYIDKEDYDLA
                     RKYCKIALASSIKNKNKFNEYKALRFYANMYKNQNEVTLAIEYLIKCIKIVSDLGNNR
                     ILANLYIDLGQLYSNISKEKELEYYQKGVFMYKNLEIM"
     gene            24041..24643
                     /gene="yedF"
                     /locus_tag="KRH23_000737"
     CDS             24041..24643
                     /gene="yedF"
                     /locus_tag="KRH23_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase-like selenium metabolism
                     protein YedF"
                     /protein_id="HHS5224033.1"
                     /translation="MSIKIDARGLACPKPVINTKRELDNLEEGVVVTIVDNETAKDNI
                     LKLAKSLSCEANIVDEKENFISIEIRKGKNILDKQNVVDNKESELDNTCIFISSDKMG
                     LGNDELGKVLIKGFIYTLTESKPYPKYVLLVNGGVKLSAENEETIENLKILENMGVEV
                     LSCGTCLDYYNLKDKLQVGTVTNMYTIVETLKNASNTISI"
     gene            24716..24979
                     /locus_tag="KRH23_000738"
     CDS             24716..24979
                     /locus_tag="KRH23_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3343 domain-containing protein"
                     /protein_id="HHS5224034.1"
                     /translation="MNQMYIVSFNSTHHAIRSEKLFGENSLKVMALPTPREITASCGI
                     SIKFSFEDMEKIKTILVENNVDIKGIYCISKLENGSKEVEKLD"
     gene            24994..25179
                     /locus_tag="KRH23_000739"
     CDS             24994..25179
                     /locus_tag="KRH23_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 domain-containing protein"
                     /protein_id="HHS5224035.1"
                     /translation="MPMDLKIGDIVELKKQHACGCKEFEIIRTGMDIKIKCTKCSRLI
                     MLDRETLEKRVKKLIKK"
     gene            25282..26478
                     /locus_tag="KRH23_000740"
     CDS             25282..26478
                     /locus_tag="KRH23_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HHS5224036.1"
                     /translation="MAVKYAKRMQGLQGSEIRELLKLTQQPQIISFAGGMPAPELFPV
                     EEMKKVSVAVLEENGRSAMQYTTTEGYEPLREKIAARMNDKNKTNVNKDDILVTSGSQ
                     QGLDFAGKVFIDEGDVILCESPSYIGAINAFKSYQPKFIDVPTDSDGMIMEELEKILE
                     TTDRIKMIYVIPDFQNPTGRTWPLERRKKFMEIVNKFEIPVIEDNPYGDLRFEGETLP
                     SLKSMDTKGLVIFLGTFSKIFCPGYRLGWTCASPEILSKFNFAKQGADLQASTISQME
                     VSKFMDMYDLDAHVDKIKAVYVKRRDVMLKTMEEEFPEGLVFTHPEGGLFTWVELPSN
                     LNAKELMPKCLDKNVAYVAGGGFFPNGGRENTFRLNYSNMPEEKIIEGIKNIAAVLKE
                     AMGVEA"
     gene            26692..26970
                     /gene="rpsF"
                     /locus_tag="KRH23_000741"
     CDS             26692..26970
                     /gene="rpsF"
                     /locus_tag="KRH23_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HHS5224037.1"
                     /translation="MRNYELVYVVKPNSDEEVREAILNKVKEVVATDGEIVKVDTWGT
                     KKLAYPIAKFTEGFYVLVNFKSAVDVPKEIDRNLKINENVIRHMIVVA"
     gene            27007..27441
                     /locus_tag="KRH23_000742"
     CDS             27007..27441
                     /locus_tag="KRH23_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HHS5224038.1"
                     /translation="MNQVVLVGRLTRDPELRYIPGTGTPVASFTIAIDRDYVKKDGSK
                     ETDFIPVEVMGKSAEFCANYITKGRLVALQGSIRVDNYQTQSGEKRTFTKVSTRSVQA
                     LDSKNKSENSYRESAPAFEPSFEPQGLDPQGFQAIDDDDIPF"
     gene            27460..27687
                     /gene="rpsR"
                     /locus_tag="KRH23_000743"
     CDS             27460..27687
                     /gene="rpsR"
                     /locus_tag="KRH23_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HHS5224039.1"
                     /translation="MMNKKRRKKKRVCQFCADKNAKIDYKSTQRLQKYITERGKILPR
                     RISGTCAKHQRELTVAIKRARNIALLPYTLD"
     gene            27830..28150
                     /locus_tag="KRH23_000744"
     CDS             27830..28150
                     /locus_tag="KRH23_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HHS5224040.1"
                     /translation="MKIDKGSEITRNIKIIEWMKTEILMSVSDLFNLLFKGVKPLDEA
                     IQDTLANIIMITYLLAKRLGISFRDVDYKVKEKIKIGIDEDHSVERWYGDLSNLKKHM
                     DNRE"
     gene            28158..29114
                     /locus_tag="KRH23_000745"
     CDS             28158..29114
                     /locus_tag="KRH23_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YybS family protein"
                     /protein_id="HHS5224041.1"
                     /translation="MNNKIRLSKAMSIIVLAIIIALVIAYIPMLGIFSMLAAVPYVII
                     GAITDRKYSLISILVTFCVLILFADISYALNICIMYSLPGIVIGKMLKRSFEQEDSNK
                     FEPIYGGTIIFVLSMLVYFFVLKTFLNVNLLDEVSKMISEIVNIQKNSFSATELKVFD
                     KMKPDEIVSYFTNMLPMMLFLQGLLSAFVTYYLSVFFIKRITKMNIRFPKFADFYLPG
                     NAILTTFLLYLLVLFIQIIGSKLYTELIMTNLQLVFNLMFVIQGIAVCIYFLKKWIRQ
                     GPNKIMFFSGIILCLFGFMGISFVGMVDSIIDFRKVRSYKST"
     gene            29125..31119
                     /locus_tag="KRH23_000746"
     CDS             29125..31119
                     /locus_tag="KRH23_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HHS5224042.1"
                     /translation="MSNKQTFKLNMPEINLYIIVIGISSIILLYYNLYVGCLFFCIFV
                     YMVFHNWRTTNIRRHEWTEYIQNLSLDIDETTKKAIINLPIPLCILEFDGNISWYNGK
                     FYDMIGQKDLLDKNIEDIVKNLNLRKVLNENKEMYTEINYKEKEYTIIYNVIKNDQEK
                     NPKYLMILYWIDKTEYLKVKQNYDDEKNAMMLIQVDGYDEVLKSAAEDKRALINVEVE
                     KILSALELNSNGALRRTSKDKFFLVMHKKELKKLEAEKFSILDTIRHIDYGNNLPVTI
                     SIGIGIDGDTLNENLKLATGALDLALGRGGDQAVVKTKDKFVFYGGKSKAVEKKTKVK
                     SRLIGHALREVIQQSDQVYIMGHKYPDMDAMGAAVGVYDICKSCNKTANIVLQSVNES
                     IEIFINKINENNYYKKLFIGKEEAIDNCTKNTLVVVVDTHRPNYTECEELLKLSEKVV
                     VIDHHRRGVEFINDAVLLFHEIYVSSTCEMVTELVQYMDEDVTINKLTAEGLLAGISL
                     DTKNFAFKTGVRTFEAASYLRKVGADTIEVKKFFNSDVKDFIIKAEIIQSTKIINNRI
                     CLAYSSTEIDSINVIIAQTADELLNIKEVEASFVLGEKDDTIFISARSLGQINVHVLM
                     EKLGGGGHIDIAGAQLKNVSLKEAYKMVNKIIEEYLEEEE"
     gene            31120..31569
                     /gene="rplI"
                     /locus_tag="KRH23_000747"
     CDS             31120..31569
                     /gene="rplI"
                     /locus_tag="KRH23_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HHS5224043.1"
                     /translation="MKVILLKDVKGTGKKGEMKEVSDGYARNFLFPKKMAVQADSVAI
                     KELNEKNKSKEIKAQKEYEEAVLLGKQMEEINIEIYSKAGEGGRLFGSITSKEIAEQL
                     KKQKDIDVDKRKILLDEPIRSLGSTFVEIKIHQKVTTKIRVDVKEKQ"
     gene            31588..32916
                     /gene="dnaB"
                     /locus_tag="KRH23_000748"
     CDS             31588..32916
                     /gene="dnaB"
                     /locus_tag="KRH23_000748"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HHS5224044.1"
                     /translation="MEDMTRIPPHSVESEQSILGSILLDKDAIITVTETIKPDDFYKE
                     AHKIIYECMITLSNKGEPIDLITLTEELRKQGHLNDIGGISYITSLSTIVPTTSNVKY
                     YADIVKEKSVLRKLIKASNEIINLGYSGATKIEDVLEQAEKSIFDISQEKTSDDFKSI
                     NLVLMDAYDMIEKLYTNKSDVTGITTGFKDLNKKINGLQRTDLILIAARPAMGKTAFS
                     LNLVQNAALKGDASVAVFSLEMSKEQLVQRMLSSQSSVELKKIKTGTLNDNDWPRIID
                     AMAVLSDAKIHIDDTPGIKISELRSKCRKLKIEKGLDLVLIDYLQLMEGEGNNESRQQ
                     EISKISRSLKILAKELNCPVVALSQLSRAPEQRADHRPMLSDLRESGAIEQDADIVMF
                     LYRDEYYHADSESKNIGEVIIAKNRHGETGSVELVWLGEVQRFGDKLRDL"
     gene            33121..33429
                     /locus_tag="KRH23_000749"
     CDS             33121..33429
                     /locus_tag="KRH23_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224045.1"
                     /translation="MEKISLIYIYPNIIKVLDEINLFRVIDNNLRESIVVYANNVDNQ
                     YHINMTNTNFGNIINICKLEKLLDVDKFMEKVIKYEKEIIEKEEFSKIEEYMLNIGEY
                     "
     gene            33511..34800
                     /locus_tag="KRH23_000750"
     CDS             33511..34800
                     /locus_tag="KRH23_000750"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004019 - adenylosuccinate synthase
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HHS5224046.1"
                     /translation="MKTVAIVGSQWGDEGKGKVIDYLATQADVVVRGQGGNNAGHTLV
                     VEGKKYALHLIPSGVLNPNTVNIIGNGIVFDPKGFLEELEMFKTDNISTENIKISDRA
                     HVIFPYHKELDALSEEARGDLKIGTTKKGIGPCYMDKTERSGIRICDLMDKDKFAIKL
                     KAQIDAKNEIVKNIYGKEELFDFETIYNEYLGYAEQIRKYVADTSVIVYDAVRAGKKV
                     LFEGAQGTLLDLDLGTYPFVTSSHPTSGGFAIGAGIGPNMIKDVVGIVKAYTTRVGEG
                     PFVTEQINETGDKIREQGHEFGVTTGRPRRCGWFDAVIVKYAARVNGLTSISFMLLDV
                     LTGFDKIKVCTSYKMGDKIITDFPASLDDLAKCEPVYEELDGWNEDITQIDNFDDLPE
                     NAKKYVAKIEELVGVSVDMVSVGPNRAQTIIRRNIFA"
     gene            35126..35201
                     /locus_tag="KRH23_000751"
     tRNA            35126..35201
                     /locus_tag="KRH23_000751"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35159..35161,aa:Lys,seq:ttt)
     gene            35208..35282
                     /locus_tag="KRH23_000752"
     tRNA            35208..35282
                     /locus_tag="KRH23_000752"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35241..35243,aa:Glu,seq:ttc)
     gene            35287..35362
                     /locus_tag="KRH23_000753"
     tRNA            35287..35362
                     /locus_tag="KRH23_000753"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35320..35322,aa:Val,seq:tac)
     gene            35396..35470
                     /locus_tag="KRH23_000754"
     tRNA            35396..35470
                     /locus_tag="KRH23_000754"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35428..35430,aa:Thr,seq:tgt)
     gene            complement(35853..36845)
                     /locus_tag="KRH23_000755"
     CDS             complement(35853..36845)
                     /locus_tag="KRH23_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HHS5224047.1"
                     /translation="MNEDKIRKILAKYAKRRDDNELLLEHRKNEVYNRIPEIKSIDDE
                     ISKIGLSLAKIVLLNPKSKDEIVKKTKENIESLKVKKERLLAESNIPLDYLEIKFQCI
                     SCKDKGFLPNGEKCSCLKQEIVNEAYKMSNLDRILSQENFSNFNLNIFSPKKGSDGEI
                     SPRENMLNNLSICENFVHDFKKDNSENLLFYGSTGLGKTYMCNCIAKELLDKGNVVIY
                     QTSFRILDILEDYKFRRDTNNQISEDNYKNLFDCDLLIIDDLGTELNNSFTSGEIFNI
                     VNTRLVAGKKIIISTNLTPSQIGNTYTQRTLSRILDKFRILEFTGDDLRWERFK"
     gene            complement(36854..37912)
                     /locus_tag="KRH23_000756"
     CDS             complement(36854..37912)
                     /locus_tag="KRH23_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HHS5224048.1"
                     /translation="MFFKESNEIDLGEITIPNIFIDIFMPMADGLYVKVYLLGYRQAC
                     DITSNPKFDNNSIAKNLNIPLSDVLSAWKFWEEKKIIKIHDNGEYDNFNYSIEFLDLK
                     NFYIENILSNNSSIKSNTDKVVSTSENPSIRKMFNSINKIVGRYLDPSEKMSIMDIMN
                     KYNMSPDMILCAYEYVKDKTGTSKPVKYIEGIIRNWYDSNLYTPKDVEESFLVRSERY
                     ILYKTIFNELGFSRQPSKSEKELMDTWFDKFNMDIDLIINACSKSKNISNPSISYING
                     IIKNWNEKNIKNLNDLKQKEEERIVKENINKKQINTTQNNNTYKKTKFHNFNETFTQY
                     TSDELDEIIKKSQKEKFK"
     gene            38037..39500
                     /locus_tag="KRH23_000757"
     CDS             38037..39500
                     /locus_tag="KRH23_000757"
                     /EC_number="3.4.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004177 - aminopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008237 - metallopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HHS5224049.1"
                     /translation="MVIKFNQKVRRTLSVAILFMVLIIGCFIEKDDSLETYKEKTNSK
                     INQYNMDVIFDDETKRLMCNQNVDYINNTKSNIDKIYFHIYPNAFSKKDFAPFEKSEM
                     TRAYPNGFNEGYIDIKNILNNNSKMEYKIKGDKNDILEIELGKELKPNERMSLDIKYN
                     VKIPNSIGRFGYGENTINVTNWFPIACVNDERGWNLKSYETIGDPFYSETSDFHVKLL
                     IPNKYKIAHTGKLIDDKHDNKKMLYEIEAENVRDFAFILSSKFDVNKVDSKGVAINTY
                     NLNKKLSKKATEVAKDSINIFSELFGKYPYKEFSVVASDFFIGGMEYPMLVMIDQSLY
                     NEKNEFLLEYVIAHETAHQWWYSAVGNDEISEPWLDEALTEYSTIVYFEQKYGKDMAN
                     KLIKTMEIQTKSYLSENIFKPANEYKNSTEYSLNVYTKGAIAFNEIRKEVGDKVFFET
                     LNEYYNKYKHKNANGRAFVELWNSKGVDINKIISECK"
     gene            39602..40399
                     /locus_tag="KRH23_000758"
     CDS             39602..40399
                     /locus_tag="KRH23_000758"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HHS5224050.1"
                     /translation="MLKYCSVGSGSSGNCHYIGYKNTNILVDAGLSGKRITTGLKDIG
                     VDADKLKGIFITHEHVDHIKGAGILSRKFDIPVFANIKTWCSMKDKLGDIKDKNMKVF
                     ENDKTYSLGDIIVRPFSIEHDASDPVGYNFYTESDEKMSIATDIGCITQNIKKHLYKS
                     KLVVLESNYDPNMLMMGSYTYALKKRVMSSTGHLSNEDAANFCVELINEGTESILLAH
                     LSKENNFPELAYETSKGVLASNDIVVGQDVKLDVLSRNDVSNVYEMK"
     gene            40412..42514
                     /locus_tag="KRH23_000759"
     CDS             40412..42514
                     /locus_tag="KRH23_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HHS5224051.1"
                     /translation="MLKRNFENVEDNKILYSIKQGMILAIPAIMTGSTALVILNLPIK
                     AYQEYLSGLFNGEVTNILNFINDSTLGIISLIILLTISYSYGKIYGSKYTVLVPIVAM
                     CSFLVFSHGNELNSYIEIFKTKWLFTSIIVSMTSSVLFVKLTESFVTSVKFHTEGADA
                     DFNMVVSAIVPFIIVVFLFSIFRVIMISLIGSSNFQDIFYNLFSNVFNKMGTNLMSAL
                     LFIFLMHFMWFFGIHGSNVLDTVAKNLFENSMAININLVNNNQLPTEIFTKTFFDTMV
                     LLGGCGSLLCLVIAIFLSEKRINVRKLAKIASIPALFNINEMLVFGIPIVFNYIMFVP
                     FVITPIILTITSYVAMSTGIVPCTVSAVEWTSPIFLSGYMSTGSIRGSLLQVFNLCVG
                     VMIYIPFIKMSQNRYTYMFKNNIENLTNLLKRYELTGEQPNLLNHNGKIGSISKMLAS
                     DLKFAMKRGEIELFYQPQVNYNGNVVGAEGLLRWKHSIGGFIYPPLVIILAKEEGFLD
                     ELGEYIINKACIDLKKSEKLLRNPVKFSVNISPDQLDDPKLPEQIKNIISSNDINPNM
                     LGIEITEQIALSGSQIIIERINAIHNLGIKLIMDDFGMGHSSLIYLQNNNFDIVKLDG
                     SLVKEILTNKRSSEIIMTIVNLSKNLDFDIVVEYVENIDQRDKLYGLGCEIYQGYYYS
                     KAIPFEEFVEYANQEREI"
     gene            42582..43061
                     /gene="rlmH"
                     /locus_tag="KRH23_000760"
     CDS             42582..43061
                     /gene="rlmH"
                     /locus_tag="KRH23_000760"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HHS5224052.1"
                     /translation="MNISIVVVGKIKEKYLKLGIDEFKKRLSKYCKLEIIELDDEKAP
                     ENLSVKEMEIIKDKEGKKILGKIKHNSYVIALAIDGKGLSSEELAKTMSDLAVRGNSS
                     LCFIIGGSLGLSDEVLGRADYRLSFSRMTFPHQMMRLILLEQIYRAYRINNGEPYHK"
     gene            43167..43427
                     /locus_tag="KRH23_000761"
     CDS             43167..43427
                     /locus_tag="KRH23_000761"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224053.1"
                     /translation="MADNCIVCGKSLSISQYSGDGKYKSCPSCSQNNGKEHVYYEYPE
                     HFGTTQKRASAKRPEGPQSHCESCRFDRGTYPKETLCREINK"
     gene            43636..43827
                     /locus_tag="KRH23_000762"
     CDS             43636..43827
                     /locus_tag="KRH23_000762"
                     /inference="COORDINATES: protein motif:HMM:NF046164.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization protein"
                     /protein_id="HHS5224054.1"
                     /translation="MTNFIEDNKDECIRFRVSKKQKELIKSMAKDSNLSMTRFLLELL
                     ELARTDKNILEKLGGNKVE"
     gene            43820..44659
                     /locus_tag="KRH23_000763"
     CDS             43820..44659
                     /locus_tag="KRH23_000763"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: protein motif:HMM:TIGR00571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0009007 - site-specific
                     DNA-methyltransferase (adenine-specific) activity
                     [Evidence IEA];
                     GO_process: GO:0032775 - obsolete DNA methylation on
                     adenine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA adenine methylase"
                     /protein_id="HHS5224055.1"
                     /translation="MSRKKNSLVAPVLKWVGGKRQLIPEIEKYFPDKYSTYYEPFIGG
                     GAVLFNFQPKKAVVNDINEELINLYKVVRDDVESLIKDLKKHRNESEYFYEIRSLDRN
                     REKYEQLTDIERASRIHFLNKTCYNGLFRVNNSGEFNSPFGKYKNPDIVNEITLRAVS
                     KYFNNNDISFKCGDFEDSLKGIRKGSFVYLDPPYDPVSDSSNFTGYAKGGFNRKEQER
                     LKELCDKLDSKGVKFLLSNSSTPFIMDLYSDYKIEIIKAKRSINSKGDKRGDVDEVLV
                     RNY"
     gene            44676..45938
                     /locus_tag="KRH23_000764"
     CDS             44676..45938
                     /locus_tag="KRH23_000764"
                     /inference="COORDINATES: protein motif:HMM:NF046848.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015666 - restriction
                     endodeoxyribonuclease activity [Evidence IEA];
                     GO_process: GO:0009307 - DNA restriction-modification
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II restriction enzyme"
                     /protein_id="HHS5224056.1"
                     /translation="MAWEQIFKKYNVLEEINNTGYFRVTASQIGEFREARLMAKFDHK
                     SQLPDIFKKHSLSILPIARGSYIISQFEAYKSFEDINTEITKVKFPEYIESIDYECIT
                     SEAMAINCAYVSGIIADFMEDERILPVVSGRMSSLEFEFIINNTKQKDKLPVYVSNSQ
                     IEIDGGYEGIENLALIEAKNSISDDFLIRQLYYPYRLWSKKVSKKVKSIFMTYSNDIF
                     SFYEYSFLDPKNYNSLVLVKQKNYIIDQEDISLGDILSILHDVKLKKEPEIPFPQADN
                     FKRIINLCELLLNDDMNKEDIVSKYDFDPRQADYYTNAGMYLGLIKKKDTNPIIYSLS
                     NIGKKIIRQKHRARQLSLVKLILEHEVFNKSIKLYIKKGESPTKNEITNLMKESYIHN
                     VKSEVTMMRRSSTVISWTNWILSLVNID"
     gene            46132..46470
                     /locus_tag="KRH23_000765"
     CDS             46132..46470
                     /locus_tag="KRH23_000765"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224057.1"
                     /translation="MIINIWKKQDLDLVKEIPKEVLSTIEDTIEIIDENYGTKRTAKD
                     LGGYVAVVDKAGIKELKQHQLKGIIPEYIDEIEGAEYISALFLCSNDFSIVVVCKKEL
                     KNLIEIDKEQ"
     gene            46555..46812
                     /locus_tag="KRH23_000766"
     CDS             46555..46812
                     /locus_tag="KRH23_000766"
                     /inference="COORDINATES: protein motif:HMM:NF020345.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mor transcription activator family protein"
                     /protein_id="HHS5224058.1"
                     /translation="MKKDKSDYRGIYAEMVEILGEEIVKMIHKHYKGQQINLPMKLHS
                     NEYVEKYIIENKDKKSLREMSRELGYSDRWVKRLINKLNKE"
     gene            46837..47085
                     /locus_tag="KRH23_000767"
     CDS             46837..47085
                     /locus_tag="KRH23_000767"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224059.1"
                     /translation="MILGVIAIILATVIFFLVNSMLDITYFGCGAIGTLWFGCFVIAY
                     IILTSLGGIFIGLLKWIVIGAVILGIIGLIAGSTNKAE"
     gene            47157..47447
                     /locus_tag="KRH23_000768"
     CDS             47157..47447
                     /locus_tag="KRH23_000768"
                     /inference="COORDINATES: protein motif:HMM:NF017894.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 family protein"
                     /protein_id="HHS5224060.1"
                     /translation="MFDKDRYLTRGVSEEIPLEIQILLWSMIVGIKIKKDYLQVFEIE
                     PIKNRLLKIEHRQEIPKYKKGHVVVNTGINSKVKIFVIDDGEYSTMMLSSEY"
     gene            47465..47752
                     /locus_tag="KRH23_000769"
     CDS             47465..47752
                     /locus_tag="KRH23_000769"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224061.1"
                     /translation="MSKIIKETKYCKVLRQAKIREDNIAYGIEKIFVKELNQEEIRFV
                     YFKDTYRQEEQLVSRPLDLPEEDLLKLIEVAIKQNVFSKEFLNNLKEIVTK"
     gene            48042..48668
                     /locus_tag="KRH23_000770"
     CDS             48042..48668
                     /locus_tag="KRH23_000770"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224062.1"
                     /translation="MKYYDLKELVPEITGVDEEDYILWQSTLKDIQRIDKLVRGISSY
                     SDTNKISESQKDDIVVLYRTLNKDREKLDILKKFARKKHLTEKESETLFDLFVNSMNS
                     KEEREEYSKHKEEVKSEELKAGVDKIISSIIETVKETEEFTYGARLKLLDSLSKHVEI
                     VIEFHKKEIQVAKELGGKEINILEEEARLDKISKKDKIRNNYPESKKN"
     gene            48818..48994
                     /locus_tag="KRH23_000771"
     CDS             48818..48994
                     /locus_tag="KRH23_000771"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224063.1"
                     /translation="MTLKRLNPVVLKKNGKLITSEEDKREERYISRELKLPTEIVETE
                     KSNTIQGVSKIEEK"
     gene            49046..50701
                     /locus_tag="KRH23_000772"
     CDS             49046..50701
                     /locus_tag="KRH23_000772"
                     /inference="COORDINATES: protein motif:HMM:NF017826.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF927 domain-containing protein"
                     /protein_id="HHS5224064.1"
                     /translation="MIEIDRELNEHEEKLNEIEKIDDDLSICYKTKQIVYDGGKTANL
                     LEIRTPEKNIDTNNVILPITTKYLDRYVEMRVPRDKAMSKREILKLSLHGANVTEENA
                     KYHIRSIDYQECKIGKSNNTHSELGFAMHDDKEIFKLDRAINEDSKYVGVLDLKPKGN
                     LEDYLKDIREHVAPYTNISLAFALGVSSAVVAKLNQYCEDVNTVLSHFVTESSKGKST
                     ATMLAISVWGNPKLGAGGLYNTWNSTENALATSLAGNYGVAYALDELSMSKIEDTTSL
                     IYNLVGGKDKARLTKEIELRKLGTWVTTIISNGEASLLSRAKNNTGLEVRVLELEGIV
                     WTEDARHSDNVKALANKNYGVFGYSFTEKLIKYPIDKLKLLFEEEKNIFKAKVKERGI
                     VDNMIERTATKYAIVTLTTRLINSGYKAYDINLDIESIRAVLVETEISSINRRGIQKR
                     ASEWLLEYVEANASKFKCGKDSNQNTDYWGSRRELPNGDLEIAVLNNKFKEIMKQGGF
                     EDTGVVLDQLKKDGMLDYEEGRLTRKRKINAISTPVYVVIVKP"
     gene            50834..50959
                     /locus_tag="KRH23_000773"
     CDS             50834..50959
                     /locus_tag="KRH23_000773"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224065.1"
                     /translation="MDNIGKLTEAEVKGSTAIEIIGEILQSYLLKEGNKESTSVE"
     gene            51115..51462
                     /locus_tag="KRH23_000774"
     CDS             51115..51462
                     /locus_tag="KRH23_000774"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224066.1"
                     /translation="MERYKQYKYEDVGVYIKPEIDDSELHIQTKLNILTEELYDYGCE
                     PITMLESNVKGDYTKLEELIEKIEWFRVSAVIIWSYSEIEEELRDKLRETCYKNGIEI
                     NAYKEDIQSLLFD"
     gene            51523..51891
                     /locus_tag="KRH23_000775"
     CDS             51523..51891
                     /locus_tag="KRH23_000775"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224067.1"
                     /translation="MNTCRMNIYSNYKNENVAIYAKKSSEKENVNEHIMGKVTWMKME
                     IEEFGVNILEFVDSHTKGEYKEINKLIELVKKSEIKAILIWDFADIPTEIVEILVDEC
                     SKRDVYLNGFLTTINTKEII"
     gene            52052..53698
                     /locus_tag="KRH23_000776"
     CDS             52052..53698
                     /locus_tag="KRH23_000776"
                     /inference="COORDINATES: protein motif:HMM:NF012464.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HHS5224068.1"
                     /translation="MTKKVAIYCRVSTVEQAEEGYSIDEQRRRNIEYCEKEGHEVFKV
                     YEDRGISGKNISGRPGLKELLQDANSGKFDLVIVWKLNRISRKLIDILNIVDTLDKNK
                     IAFRSLTESFETETPAGKLQLNIMGAIGEFERGTIAENVKMGMMERAREGKWNGGKVL
                     GYDIVEIPSEGKKRKDTKLVINEKEAMTVRRIFELYSEGHGYKATVNRVNKEGHRSKK
                     GNAFATATIKEILKNQVYIGKIRYNLRQDWNEKRRKNINPDPILVDGEHDAIIDTETW
                     ERVQIILKDRSKTHNRVYDSELILSGLLKCPVCGASMTVSRSTRKRKDGTKAVNEYYS
                     CGNWKNKGTAVCNSNSVKAEVADEVVINKLIETVNNELLLKKVINNINKNKSSKLKPK
                     LDEMNLVNKEIDKLNGKKNSSIELFEDGILAKSELAERVKKLNEEIDTLKFRLDEIKQ
                     EVMLAEGEPIPFELVSQVMKKFGEVFKESSTRQQRKQLLNLLVSKVTIDKSRKIDTIE
                     LQINEDVIRYLVKEGSSEEDEDPSFFHVSMFNCTTLKFVI"
     gene            53730..54395
                     /locus_tag="KRH23_000777"
     CDS             53730..54395
                     /locus_tag="KRH23_000777"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224069.1"
                     /translation="MNNTSKKIIIRTFWISVLSIVIINGINYISIKSLPIAHNSDWIP
                     FYGSFIGAILSGIVGGLITLEGVKETIDDSKEARKIDERQRIRPYLHMELESLDGSSK
                     DIKIDIKNTGENRGNSKYRIFSIRLKNIGLESCVNIRMNDKIIENSLQKGFLTREFTI
                     NSEFYDGEESINNIPVEITFEDLMGNLYKQEYCINFLGNVEYNKLRRIQNNTSPIYIE
                     TRK"
     gene            54590..54901
                     /locus_tag="KRH23_000778"
     CDS             54590..54901
                     /locus_tag="KRH23_000778"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HHS5224070.1"
                     /translation="MIKIMLACSAGMSTSLLVTKMESAAKENGIESQIWAIPESTIQN
                     EIEKCDVLLLGPQVRYVLPKAQEIAKPYNIPVEVINMMHYGTVNGEAVLNRAIELNNT
                     K"
     gene            54949..55266
                     /locus_tag="KRH23_000779"
     CDS             54949..55266
                     /locus_tag="KRH23_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HHS5224071.1"
                     /translation="MDEKIIEISFNIIGYAGEGKGLAFEAIKEAKNGNIEKAKELLKE
                     SREVINKAHRYQTELIQNEASGNRTEISVILIHAQDHLMNGMNFQQLAEEIVDLHLKL
                     QDK"
     gene            55479..56180
                     /locus_tag="KRH23_000780"
     CDS             55479..56180
                     /locus_tag="KRH23_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HHS5224072.1"
                     /translation="MLRNQPLYIQVVDILKQKILNNEYKIDENIPTERELEQEFGVSK
                     ITIRKAIEILESEGYVEKKSGKGTKVISNSLFNKLSKAESFSSILLSKGHKLSKETIS
                     IEKIINDTNSQVFSIFGEKCSKITRMYYLDSKPYIFFTHYIPFDENLTVESFNNESSL
                     YMYLYRRNINITRFEDEFFIEESELEVSKALNLAKDILLGRKRKTYDENDNIVELSFA
                     RYNTEVQNYVIKYEI"
     gene            56404..57705
                     /locus_tag="KRH23_000781"
     CDS             56404..57705
                     /locus_tag="KRH23_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HHS5224073.1"
                     /translation="MEKFASFLERKIMPVAAKISNQRHMRAVRAGIIATLPLTIVGSF
                     FTILLNIPIDAYMDFIAPFKAILDIPFRYTVGFLSLYATFGIASSLAKSYDLDTTGVG
                     MLAVMAFLVSTIVPTQVVEPVGGVIEAGRWMDMAKLNSPSLFGAIVTSLITVEIYRFM
                     KEKNITIKMPAGVPVEVSNSFTALLPTAVILMLFWVIRHILGFDISVALSAMLSPLKG
                     FLSGNSLGGGLLTVFLITLFWVLGIHGPAIMGPVIRPIWDMSIAENITAFTEGVSAHA
                     MPNIFTEQFLQWYVWIGGAGATLALVVMFMFSKSQYLKSLGRLGFLPGLFNINEPIIF
                     GAPIVMNPILGIPFIIGPIIMTILSYVLTITGVIPMMVARLPFAMPAPIAAVMSTNWS
                     ILAGILVLINFVISFAVYYPFFKVFEKQQLQREQEEMSENL"
     gene            57842..58936
                     /locus_tag="KRH23_000782"
     CDS             57842..58936
                     /locus_tag="KRH23_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HHS5224074.1"
                     /translation="MERRLGISVYPEHSNMEDDKAYIKMASKYGFKRIFMCMLSITRP
                     KEEVKKHFKEIITYARELGFEVILDIAPNIFDILQISYDDLTFFSELNASGIRLDYGY
                     DGSKEAMISFNPYDLKVELNMSNDVAYLDNIITYKPNVNNIYGCHNFYPQRGTGLPYD
                     FFVRCSNRFKKYGIRTAAFVNSKYATIGPWNINDGLCTLEMHRNLDIATATKHLFATG
                     LIDDVIVGNAYASEDELKRMSEVNEYQVVFNVVAEEKTSEVEKIIMVNEQHFRRGDIT
                     NQVARSTEVRKKYAKENFPKHDNMTIFKRGDVVIGNDDFGKYKGELQLILQDCADERK
                     NKVGRIKKDEIMLLDFIEPWSKFKLILEGE"
     gene            58938..60071
                     /locus_tag="KRH23_000783"
     CDS             58938..60071
                     /locus_tag="KRH23_000783"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase/deacetylase family
                     metallohydrolase"
                     /protein_id="HHS5224075.1"
                     /translation="MKIDILIKGGKTVDKSIIDIAILDDKIIEVKNQIDDSKYQANQI
                     INLDGEKFISAGWIDIHTHCYERLDLYKDYPDEVGIKSGVTTVVDAGTTGALDIGEFY
                     EDTKKYKTNVYALINIAKQGITSQDELSSMMNIDEYELKRAVKKYKDFVVGIKARMSK
                     SVVISNDVEPLKVAKKIKNELNLPMMVHFGSSPPTIEDIFDYMEKGDILTHIYNGKPN
                     GILRGNEVKKEIIEARERGIILDVGHGTESFSMDIAMKSKDAGIFPDTISTDIYIKNR
                     INGPVYNLSTTMEKFIYMGYSLEDIIDKVTKNAADAISLKNKGLIKEGYDADLTIFDV
                     VNEEKELQDSLNKSVITSTSIKPRAVVVNGEYLNIGKSIGENE"
     gene            60089..61198
                     /locus_tag="KRH23_000784"
     CDS             60089..61198
                     /locus_tag="KRH23_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DgaE family pyridoxal phosphate-dependent
                     ammonia lyase"
                     /protein_id="HHS5224076.1"
                     /translation="MSSIFEKYSVRRVINASGKMTILGVSTVDKEVIEAIGEGCKNFF
                     IIEELINKTGEYIANLLGCESALIVSSASAGIAQSVGAMIAKDDMSLVYNVNNPKKQV
                     KREIIIPKGHNVDYGVPVEVMIRLGGGEVVEAGYANMCNKEHIIREINENTAAIMYIK
                     SHHCVQKSMLSVLDAVQVAKEYNLPLIVDAAAEEDLNVYYELGADLVIYSGAKAIEGP
                     SSGLVIGKKKYIDNVKLQSKGIGRAMKIGKENIVGLTCAIERYISNDKVTLKEMEDKL
                     NPFIDKINTIKGVSASITRDSAGREILRGEIDFNEDIINKSTQQIINELRSGEIAIYT
                     RDYKANEGKIEIDIRSVTGSDLDTIYNRIKNIVES"
     gene            61263..62003
                     /gene="dagF"
                     /locus_tag="KRH23_000785"
     CDS             61263..62003
                     /gene="dagF"
                     /locus_tag="KRH23_000785"
                     /EC_number="4.1.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008675 -
                     2-dehydro-3-deoxy-phosphogluconate aldolase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HHS5224077.1"
                     /translation="MNCIPQYYKNRVCLNVLAGSIKNAKEVYDACDGHVLIGVLSKNY
                     STVEAAIEDMKKYSKEIDNAISVGLGAGDPNQSNMVSQISKELQPQHINQVFTGVATS
                     RALLGQNDSIINGLVSPTGKPGFVKISTGPLSSKEKDGIVPIETAIAMMKDMGGSSIK
                     FFPMGGLKTKDEYIEVAKACAKHNFYLEPTGGIDLDNFKEIVQIALDAGVEKVIPHVY
                     TSIIDKETGETKVEDIGVLYKIMKELLG"
     gene            62008..63000
                     /locus_tag="KRH23_000786"
     CDS             62008..63000
                     /locus_tag="KRH23_000786"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0019200 - carbohydrate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HHS5224078.1"
                     /translation="MNILAFGEIMMRLSVPDYKFLTQTNELNYIITGTGLNILSGLKN
                     FGYNTYMLTKLPNNNVGKASSANIRKLGVKDDFITYGGNHIGVYFLENGYGERPSEVT
                     YLNRLNSSFCESKLQDYDIDKCLEGMDIVHICGIAMQLTDSVKEIALELARKSYEKGI
                     KVFFDFNFRQSLNPERTYDDLVNDYKKILPYCHGLFASYRDINKILNIDSLNIKSSSE
                     LIKKEYDIGIVAGTMRRFDDMNNRFIKGYISNDDGYFESREYKLEIYDRVGAGDGYVA
                     GIIYSYLENMKSEDIVEFGVASSVLAHTTYGDNSLVSTGHVLRLMNNEKIDILR"
     gene            complement(63188..64069)
                     /locus_tag="KRH23_000787"
     CDS             complement(63188..64069)
                     /locus_tag="KRH23_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HHS5224079.1"
                     /translation="MNTKQLEYFISVAENLSFTKTAEKFYISQTAVTQQIKALEEQIN
                     VTLFTRSKRHVELTPAGKVFLSEARTIIKNINDAIAKTQQFAHGFFGTLSIGTLIGYE
                     KNKLQQYLKEFSNTYPNISMDICTNEITELLNLVKNNSMDLAFVINPENQPLKDFEYK
                     TVERYSLVALLPPGHTLYNEDSIDLIELQHDKFIFVKETGDEYGQKSMIQNRYREAGF
                     VPNVVQRSNNLNTIESLVSSNMGISILPSFCVTDTMIERDIAIVPIKEVENRIEVVVV
                     WNKKNTNPALEKFISII"
     gene            64342..65730
                     /locus_tag="KRH23_000788"
     CDS             64342..65730
                     /locus_tag="KRH23_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LVIVD repeat-containing protein"
                     /protein_id="HHS5224080.1"
                     /translation="MEDKFYAKGNGNNGYIKNLEVCSFNNLDGTCGMFQMALYKRDEK
                     YYLYGCCFGGNKKNGVMISDITDPYNPQFIKHFQMLDPKEYPTTTTPKIQIADDLMIV
                     AMSCGSGPGALVDQAKLANIKCEAGIRIYSLKEDPLNPKFLGYWDCGLKHVMGVHRFM
                     YNGGRYVHLSSDCVGFEGLIYRVIDIINPTNPVEIGKWWRPDQYADGYPNRTFDAGAP
                     HCPEFMDKGWLHGPPFVRDGKAYCGYGGAGLVVLDVEDLTRPRCLGELPFTPAFSSRL
                     AGARTHTALPLPGRDLVVVQNEGERFQFFKPDNITDVQAMNNIHMVDVSDPTKPTLIA
                     QFPYPEVPKDFPYPNFNVAGLGKPGPFGPHNLHEPMDNKPWLEQRGDRVYCCYFHAGL
                     RVYDVSDPYYIKELAYFIPPNPNKTPEESYFPGFPGPRLAVTEDLIVDDRGYIIIDAL
                     DDGFYILKMKED"
     gene            65758..66711
                     /locus_tag="KRH23_000789"
     CDS             65758..66711
                     /locus_tag="KRH23_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HHS5224081.1"
                     /translation="MKILGISFGTKNGNNDTMCKVALKGAKEAGAEVEFIQMSSINIK
                     HCTGCCACVKTLLSGKGSMCVLKDDFEWLLDKMKDADGIVVSDPIFEEGASGLFHTIM
                     DRFGPRADRGNNIIGTKVAEAIGGKIPDSRMLNDKVISFMGIGGSDWGTRVQCEHAML
                     ALIPMWKVIDNAWFPWAKELVMDDTRLVQVHQIGLNIVEAAKDFEKASYQGEEGVCPH
                     CHNRLFYLEPGTKKAICALCGIVGELDTISGKTIFSFPEEQLGHAHDTLPGKFIHGDD
                     IKKMEGHYAEVRKTQEFKERKTSYNFIEPLTKEKQAGVSLR"
     gene            66771..66995
                     /locus_tag="KRH23_000790"
     CDS             66771..66995
                     /locus_tag="KRH23_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224082.1"
                     /translation="MNEKSSFKQIEIILAVIFLVLTYYKVRLTPAFIVIFIPLYLSYF
                     AVSMIVNQIAIKLLEIRQAREATNYNIGNG"
     gene            66988..67500
                     /locus_tag="KRH23_000791"
     CDS             66988..67500
                     /locus_tag="KRH23_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1097 domain-containing protein"
                     /protein_id="HHS5224083.1"
                     /translation="MDRKKKEILTLSMGIALLPPLWAVLAPYIGIKTGAVALICAGLY
                     VTNGNKQKDGLKIMFGFWCGDLWAVLAILIMGYMNFNQNLELFLTLSILGFFAVVIAS
                     LFEKIIFLPSWLCGWAIGLTIMTGENIINLQDICIQIAVAMAVGVWYVGAGVDLFTIY
                     ILSKDRKKGN"
     gene            67532..68386
                     /locus_tag="KRH23_000792"
     CDS             67532..68386
                     /locus_tag="KRH23_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA hydrolase"
                     /protein_id="HHS5224084.1"
                     /translation="MAMGFEFKIMRSLIYVGLAKEEYRPKLMDWLYRHHIPDSISTFG
                     PYCTKYAFYQAYPTPNEGERFGARKMQLTEHYWLVDEHMPEMANRIMTEYMPMDVLRW
                     QGCIPDVENKRVHENAESGDAGRAVGGDNGCPPFIFAFVPINWEEDFRGKGRTVQDGP
                     NYRWQFMIKYPDGISKEEGEKWFYDEVVPYFTNCCYVNRFVSSKIMINYGATAFDRVS
                     ELWFEGEEEWYKAVVEETKSFIKKPEWAQEEEFPYLKPQFNIASVFLGDIATMDAYSQ
                     YRGYIPMR"
     gene            68920..69714
                     /locus_tag="KRH23_000793"
     CDS             68920..69714
                     /locus_tag="KRH23_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HHS5224085.1"
                     /translation="MYTIGQVSKFLGISRDTLKFYEDKGLVNPKKNDENGYRIYNQVD
                     IYDIATINFYREIDIEIKKIQEIRKSKSINNLELLLEEKEQIILKEIEYKKLLLKKVQ
                     LVKEDCDKIKTYFGKYTIKEMKPLEVKGKIKHVTNYEEYEALKENTNNLKKAVTLTDL
                     RRVINFNEEGIIEEKFIIVREVDDYNKIIEGEVLSHPNCIYTIIEDGRWSTGGENIDN
                     KVEDRLREIAIENECELLGIVYVNILLTTYEEGIERIFLEIYAPIK"
     gene            69818..70624
                     /locus_tag="KRH23_000794"
     CDS             69818..70624
                     /locus_tag="KRH23_000794"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0071586 - CAAX-box protein processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane glutamic
                     endopeptidase"
                     /protein_id="HHS5224086.1"
                     /translation="MRTEKSLKRPIASFIILTNIIFLPLFLLVVVTIMLKLPTVISDI
                     ALCISAWSSTFAFMILFKKIYPGKKFLVHVKDRFRNKLKFSTVSIIISIQVLIAVVVI
                     FILASKNHGIMPNFTVSSWGAFIYLFLKNLFAGSLGEELGWRGFVQNHLQKRHSPLKA
                     SIIVGFWWGMWHLPIWFTTGFKGLDLIKYIIFFMIAIISISIIMTTFYNLNKTLIIPI
                     VIHQLFNFLIGIINGDLIELINYYAMLYLIFAIALIVINPGNVLYKNIRE"
     gene            70686..71207
                     /locus_tag="KRH23_000795"
     CDS             70686..71207
                     /locus_tag="KRH23_000795"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase family protein"
                     /protein_id="HHS5224087.1"
                     /translation="MVLLIVDAQKLITNERLYKFNEFVVNVENLIDTARKNNIEVIYV
                     RHDDGVENELTKGKNGFEIYEKFKPCNGEKIFDKKVNSAFKETGLLEYLTNNGEKDII
                     IAGLQTDYCIDATIKCGFEHGFNIIVPAYSNTTVDNFFMSAEQSYKYYNEFIWNERYA
                     KCISLEETLRKMK"
     gene            71622..73709
                     /locus_tag="KRH23_000796"
     CDS             71622..73709
                     /locus_tag="KRH23_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HHS5224088.1"
                     /translation="MVVDKEIVSILQILLNSTLITTNGLQEEFNSSKRQITYRINKIN
                     DMLKVKNVPLICLRADKDIIVRKETKKAIKEILEKNYSKNTYYFSKTERLLYMYLMLF
                     INMEDISINHFINSIKVSRSTVNLDFKDLIPELEKKNIKVKNNRINGYYIVGNEMEIR
                     RVLIKNIIETLSNEKSSRVFDIFIKEYNLDSFEEAKKIILKLIKKYEITFVEDRLVEF
                     IYIFIFLKARMYSTRIVTQENVDIPNISVMSSMKEYKFAKELLEVYGSEDKIKPHNIM
                     YISAWILGISVGNYEEDTEDKDVISKIVNKMMTKFGYLSGVYYISQEKIFKQLYSHFR
                     PAYYRLLFKLPIYNPICEKVKEEYKLVYRIVSNAMKEFCGLFGEEIQEEELAYLTMHF
                     ATLFSNKKEFDGFRKRIALIVCSNGVGSSAILHAELTNLFPDLHFIPMSESVGLENIS
                     EPVDIVFTTNYNAEGLKTDVPVIKVSPVMTTKEKYKITREVYIQLGDIYLRQPKIDEV
                     MDIIKKYANVTSESILSSELLAYFTQIENFTSKEGEGPMLSEITNETLVKIKVKAKNW
                     EEAIRQSASVLVENNKVTEGYVDAMINSAKASGPYIVITKHVALPHARPEAGSKEIAI
                     GIATLDSPIEFGNNENDPVKYVFCLSAIDNNSHLRAMSELVELLEEDEFFKVLDSAKE
                     AKEIIDFIKTHEL"
     gene            73724..74011
                     /locus_tag="KRH23_000797"
     CDS             73724..74011
                     /locus_tag="KRH23_000797"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HHS5224089.1"
                     /translation="MYKILIACRAGVGSSLMLKIKTQQIIKENNFPIEVEHGSLDSLN
                     GFNGDAVETLIDVAEELKNKNLKFDIIGIHNIVDRNEIKTALEKFLASKEG"
     gene            74038..75309
                     /locus_tag="KRH23_000798"
     CDS             74038..75309
                     /locus_tag="KRH23_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HHS5224090.1"
                     /translation="MEFIISLLSTPAVLLGVVACIGLILQKKSAVEVFTGSSKTLIGF
                     LIFGIGASAMTGALQNFNKLFQHGFGITGVIASPEAATALAQGTYGFAVSCTLILGFI
                     LNLVFARITKFKNIFFTTGHSLFFSCVLVLIMKAHGFDNTITILIGGTILGFMSAALP
                     QFCQPFMRELTGGDEQAIGHFNMIGYGLSGYIGRLFSKHKDDTTETIEFPKWLSIFRD
                     FLMGLSIVMLILFYIATLKAGQAFTQEIAGSTHWLVFPLIEAFTFVAGMSILMSGVRM
                     FLAEITAAFVIISEKYIPGSRPALDVPTVFPYAPNAVIIGFISAYAAGLLAIAIMASF
                     PSIFPVVIIPAAHICFFSGGTAAIFGNTSGGWRGAIAGSFVVGLLLAFLPVILYPVYG
                     TLGIEGATFPNIDYNVVGSILHNILQFIKPI"
     gene            75367..75966
                     /locus_tag="KRH23_000799"
     CDS             75367..75966
                     /locus_tag="KRH23_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HHS5224091.1"
                     /translation="MENTLSEFLDNISNELSEFIASIDETSINKACELILEAEKNHGR
                     VHVTGIGKPGHVSGYISSLLSSTGTSAYILHGTEAVHGSSGQVVEGDVVIAISNSGET
                     QELKATLKTLKVNGAKIIGVSGNESSFLKNISDIFLFAGVKQEGDCLNKAPRASILAE
                     TIILQSLSVVLQYAKGLNTQQYLKWHPAGSLGKSIREGI"
     gene            75971..76876
                     /gene="dapA"
                     /locus_tag="KRH23_000800"
     CDS             75971..76876
                     /gene="dapA"
                     /locus_tag="KRH23_000800"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008840 - 4-hydroxy-tetrahydrodipicolinate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HHS5224092.1"
                     /translation="MKYKGIICAMITPFDENQNINSQATCQLIDYLIEKGIYGLFILG
                     TNGECHVLTDDEKVEFAKIVINHTNNRVPVFVGTGGNSTREVVDLSKRMEAIGASALS
                     IITPYFVTPTQQELILHYKTIANSVNLPIIMYNMPGKTGINIEPESVRELSKIKNIVG
                     IKDSSGKLDNMKSYIEATKNENFSVFSGSDSLILDSLKAGSQGAVAATTNFLTEIGIS
                     IYENFMKGDLEEAQKAQSSIEELRRILKLGTIPSVMKKTIVLNGINVGTARLPVTEPT
                     GEVLEEIKRVVENYRTILNKSSENR"
     gene            76982..77614
                     /locus_tag="KRH23_000801"
     CDS             76982..77614
                     /locus_tag="KRH23_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketohydroxyglutarate aldolase"
                     /protein_id="HHS5224093.1"
                     /translation="MKKMNITKRMSECGALAIVREENLNRACEIAEGCIKGGITVIEM
                     SYTLNNAGEIIQGLNKKYGETLCVGAGTVLDSETARHAILHGAQFIIAPNYNEGVAKI
                     CNRYQIPYAPGCTSLTEAVDALSLGATFIKAFPISDFYGPKLVKVFKTPIPDMPVLAS
                     GGINIENLHIWLENGVDVCGFGGLLTKGSVEDIAKNANKIREIIKNIRKI"
     gene            78092..80599
                     /locus_tag="KRH23_000802"
     CDS             78092..80599
                     /locus_tag="KRH23_000802"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase domain-containing protein"
                     /protein_id="HHS5224094.1"
                     /translation="MKEDIRLHRMCKKEQATKNEVISEDILKSMSIGVSKHFLDDSFT
                     IIWGNTSFYQLLGYTEEEFLVKFSSLKDYYEQNLYHFESMKNHFLEAYHHGEKSIEYQ
                     ICISANNGDPVWVIMTGILIESQDNEKSMVYILYSKINELKIKQEELSDMEKESTENF
                     KWMMSEYAGNVYISDMDTYELLYLNKHSCNTLQASANELIGRKCYEVIQGRTSPCPFC
                     TNSYLKKDDTYEWEFYNKKLKRTFIIKDRMLNWQGRRVRIELSYDMYSAEYKLAKKDQ
                     ERESILKTIPAGMVRLDARDYLTILWCNDIFLNMIEYTKEQFAEELNNQCGYLFSEDY
                     KRSKKLAQDLKESGDNVVFEAKIYTRSREERIWTVTLCYISGEDSWDGIPSFYSIGID
                     ITKERKQIEKLQHISEKDALTGIYNRAETERQIKKYFEKNLNVMGALFMIDTDNFKQI
                     NDTEGHMIGDIVLTEMASGMKKIMRDSDVVGRIGGDEFTIFMKNISSVKDAEKKAEEL
                     LYMFRHLFQKEKSFLKVTCSIGIAIYPKDGTTFKEIYARADKALYQAKNMGKNNYVIY
                     NQDYFKELEEFDCSSLGTVIDSEKQYAECPDNLTRYIFRMLYQTDDIDQAINMILEVV
                     GKQFDVSRVYIFENTEDGRYTSNTYEWCNEGISSQMAYLQNSNYQDYEDYEKFFEDES
                     VFYCRDIHTLSPKLEELFSSQGIHSTLQCAYKEDRVFSGFVGFDECTGLRLWSQEEIS
                     TLSLISQIISMFLQRKKNNKLNQQIQQYQNILDNIDQCICVINKENNFLLYVNKKFKN
                     TYSKFQIGQPYYLDSIDIHKISIIWNKKEAYLCTSTI"
     gene            80941..83103
                     /locus_tag="KRH23_000803"
     CDS             80941..83103
                     /locus_tag="KRH23_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HHS5224095.1"
                     /translation="MKKIIYVLFTIELLIVSLLGLNIVKDNEINNILYNDTTSISVMF
                     KDYKKLNKNYSKWIKDIADENNVAISKYVFNNNEKLSIYTTDTSLNNNIKLKSGKFLN
                     TNSNEFISNINTNNSNQVGKFSTMSKDISILIRDFGKISEVGESGILYISTQNEDTIN
                     KILRELNVDRSIFVARLHDRYVNSNLYLNPSIIRDLILIILCFLATIIHYSISVSREA
                     SILRLNGYSKLDIIARVIKNILRIMILSSVTALLIYIIYILKLNIGVRACLYFAMFSI
                     ICILINILISILIVGFNSRSSKYVLSLNGKKSYGFVNIMHFTLKIVFVSFLILSINNC
                     ILNYNMLQTQLGNLSEWDKAKNVYNLTLKDTGEQSLGKEEVIKNAKIKGFYKNLVEEK
                     DAFLIDSTNFEKLEDGSYMYEINSKGKNPEVSQYGKNIKINKNYLKVNPIYSNGKEIF
                     NLIDYDDKTINLLVPKKLQVHENEIKKEFRELFYFEKIEVENMYNKELNRELNKTKKS
                     DLNVNIIYVDNNQSYFTYNSLVMDDNRNLIDDPIAIVDIDNIDDSFYLSYISRCVYFN
                     SKKLDALADISSIIEAQGVEAHIQSLHAVYNEYGLEINKLEKYLNSEIFTIIIIAISN
                     LMITYNIVASYYERNKYKLYIKKIFGYSTTARSMLLIVSLILTNIIPIGIISTRVDLS
                     NNIILFGLLILVIEVIVSIVLDKIISNSSFNKIIKGEH"
     gene            83108..83725
                     /locus_tag="KRH23_000804"
     CDS             83108..83725
                     /locus_tag="KRH23_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHS5224096.1"
                     /translation="MISLINISKKFKDKSIIDKFNLEISKGEFVAITGNSGSGKTTLL
                     NIMGLLEKPNSGDIIINNIKNPNSKQIRILQRDFYGYLFQNYALIENENVENNLKIAL
                     KYQKNINHNEKINYALESVGLRKYNKKKIYELSGGEQQRVALARVILKECEVIFADEP
                     TGNLDKKNRDIVFDILKSLNKNGKTIVFVTHDLDLSEQADRVIKL"
     gene            83914..84258
                     /locus_tag="KRH23_000805"
     CDS             83914..84258
                     /locus_tag="KRH23_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein YjdM"
                     /protein_id="HHS5224097.1"
                     /translation="MENLPNCPKCNSEYTYEDGTLLVCPECSHEWALGLGDEEDSNII
                     KDVNGNVLNDGDSVTVIRDLKVKGSSSSIKIGTKVKNIRLIHDSSDGHDIECKIDGFG
                     AMKLKSSVVKKA"
     gene            84828..85694
                     /locus_tag="KRH23_000806"
     CDS             84828..85694
                     /locus_tag="KRH23_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HHS5224098.1"
                     /translation="MIDIHKNIYDNKLFEELKIDCKKCFGLCCVALYFSASDGFPIDK
                     ESGKPCINLQPDFKCSVHNSLMKRGFKGCTAYDCFGSGQKVAQVTYKGIDWMQSSELT
                     NQMSEVFLIMRQLHEMLWYLKEASVLNISDTIKSKIDLIIEETEKITNMGPEQIINLD
                     IISHRTKVNLLLSQASESVMGKVKSFIKTSTLKNMKKLSKNIDLIGADLRKINLIGAD
                     LRGRFLIAANLRNTDLSGANLIGADLRDCDIRGANLENSIFLTQLQVNTAKGDSSTKL
                     PASLIRPKYWEK"
     gene            85807..86211
                     /locus_tag="KRH23_000807"
     CDS             85807..86211
                     /locus_tag="KRH23_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YmaF family protein"
                     /protein_id="HHS5224099.1"
                     /translation="MSYQNYKCERDYVYDDYKYNKCNKCYNDYEEMTHVHEYSESVKL
                     AEECEDRHNHRAAGVTGEAIPINGGTNHVHKINDNVDFLDHFHKICVTTGPAIRIPGT
                     DKHIHLICGETTVNDGHCHKFLFTTQIEAPLV"
     gene            86375..86824
                     /locus_tag="KRH23_000808"
     CDS             86375..86824
                     /locus_tag="KRH23_000808"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HHS5224100.1"
                     /translation="MKSGIILEMKQINSTEYDEMLQVWESSVRATHDFLTEKDIESLI
                     PLVEIGLKEVENIVCIKDNDIIKGFIGIDKDKIEMLFIEDKYRGNGIGKKLIKYAIDK
                     YNVKYVDVNEQNKKAVGFYIHLGFKVFDRSEIDGQGNPFPILHMKLI"
     gene            complement(86980..87357)
                     /locus_tag="KRH23_000809"
     CDS             complement(86980..87357)
                     /locus_tag="KRH23_000809"
                     /inference="COORDINATES: protein motif:HMM:NF018663.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HHS5224101.1"
                     /translation="MLTPYLIFNGTCEKAFNFYAEAFGGGKTIFARLDSNPNNPIMHA
                     SVTFTKYEGCIMGADTDKPVVISGMAICVVLPSREAIEEISVKLAEGGTLVQEFLPHP
                     PPHQNDGATEVLDRYGYTWYLST"
     gene            87811..88536
                     /locus_tag="KRH23_000810"
                     /pseudo
     CDS             87811..88536
                     /locus_tag="KRH23_000810"
                     /inference="COORDINATES: protein motif:HMM:NF021537.6"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2268 domain-containing protein"
     gene            89020..90438
                     /locus_tag="KRH23_000811"
     CDS             89020..90438
                     /locus_tag="KRH23_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006813 - potassium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="potassium/proton antiporter"
                     /protein_id="HHS5224102.1"
                     /translation="MTELMIISGLVLLICITSSKVLYKFGVPILLIFILLGMLFGSDG
                     MVGIYFDNYELTKQLCSIGLIFIMFFGGFGTNWNMAKPVAIPSILMSSLGVIITAGVT
                     GMFCHMVIGTSLLEGLLIGAIAASTDAASVFAVLRSQKLNLKGSLASLLEVESGSNDP
                     IAYMLTLILLTLMNNSGVELIAPMVIKQIAFGLAIGFILAKLSVYILRHSNFEIEGFY
                     TIFITAIAILSYAFSEYLGGNGYLSVYISGIIIGNSRIPLKKSLVHFFDGISWIMQIM
                     LFFMLGLLSFPSKLPNVFGIAMAISIFMIVIARPLATFIVLAKFKFSNKEKLFISWVG
                     LRGAASVVFAIYAVTQGVAIENDIFHIIFFIALLSVGIQGSLIPTVARKLDLVDDNTP
                     VLKTFNDYDGEISSKLIEVNVDEGNKWANKSIIDSNIPDDILIVMIKRKEQVLIPKGS
                     TIIKTGDILVLSGDRIEELIQL"
     gene            90514..91326
                     /locus_tag="KRH23_000812"
     CDS             90514..91326
                     /locus_tag="KRH23_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HHS5224103.1"
                     /translation="MFSIGMFSKINKITTKTLRYYEDIGLLKPEYVDEFTKYRYYTTE
                     QLPKLHQIITLKQMGLSLAEIKKAVENPEEVENILMNKEKEMLDVIKSEEYKIIKLRN
                     YLMNLKGEVNMNDVIIKSLPKVKVASMRKVLKGYDELFNLFPNVMAEEMMKTGCTCAV
                     PDYCFNIYHDGEYRETDMDVEMCQAINDLKEDTDILKFKELDAVENAVCILHNGPYST
                     LGKTYADAFKWIEDNKYKVVGNPRESYIDGIWNKESEEDWLTEVQIPVKRML"
     gene            91749..92366
                     /locus_tag="KRH23_000813"
     CDS             91749..92366
                     /locus_tag="KRH23_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 family protein"
                     /protein_id="HHS5224104.1"
                     /translation="MEIFAIGHSNYPYDKLINMIKKYDINCVVDIRETPYSKYNIQYN
                     KEAFNESLRNSGFLYIYMGKEFGAKRTNKDVYTQEGYADFEKVAKEDIFLNGIERLKK
                     GCQMGYRIVLLGAMQEPIRCHRSILVGKVLNKEGFDVKYIMHEGNLAYQEDIEESLLD
                     KYFSDRKQLSIDNLLGSALTREEMIQEGYKLANKEIGYRTEKLGK"
     gene            complement(92523..92975)
                     /locus_tag="KRH23_000814"
     CDS             complement(92523..92975)
                     /locus_tag="KRH23_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="staygreen family protein"
                     /protein_id="HHS5224105.1"
                     /translation="MVNLNANNLNVNMVYPISSTAPIRFRRYTVSYLENMENIYLTIA
                     TYFDTLGLGTMNIDKVYGQWAWFTDNIYDLNLFVFVGNYPYQIAKNRYDTFVDILPVA
                     ITSIVNGDRVFLISNPCLLNSKITVRFISSHPTLNRTVDYGNIRDFIF"
     gene            93423..94781
                     /locus_tag="KRH23_000815"
     CDS             93423..94781
                     /locus_tag="KRH23_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042910 - xenobiotic transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006855 - xenobiotic transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HHS5224106.1"
                     /translation="MFIRKNVIKLAIPIMIEQTFVMLLGVFNTMMAGHIGEEAVSAVG
                     MVDSINNIFISVFAALSVGATVVVAQQIGKKDSEKVNETIKQALVSGVILSFTITILM
                     WVFRTGVINLFYGSAEELVKSNAKLYIEFTLFTYPFIATQQIANGILRGCGDVKKPMY
                     VTMFMNIVNVTLGYILIYGIDLNPLGINLQTPSYGITGAAISIAIARIIGCIVIIRAL
                     FKGNEFISMGKIFPFKIDVETQKSIFNIGIPAGVEQLLFNAGKLIVQVFIVTMGTSAI
                     ASNAIGMSIASIINVIGNALALSATTLVGQYIGRGDIKGAKSTLLYLTKFATICLFIV
                     GAIFIPIAPWISSMYTQNASVIDISTQLIRSDCLAMVIWPISFVLSAGLKGAGDTRYT
                     MMTAVIGMWIFRIFTGYVLGVVLEFGVLGIWIGMYTDWLVRGTLYCLRLRGTKWLKHK
                     VA"
     gene            95054..95434
                     /locus_tag="KRH23_000816"
     CDS             95054..95434
                     /locus_tag="KRH23_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HHS5224107.1"
                     /translation="MINKIGKITLYVNNQEDAKLFWTEKLNFVVTYEKEMGPNMKWVE
                     VAPSKNEFTTFVLYDKNLMMKQNKEINVSHPSIILSTRDINGTYEQMANNEVEVGELM
                     EMPYGRMFSFKDQDGNDYLVREDK"
     gene            95559..95759
                     /locus_tag="KRH23_000817"
     CDS             95559..95759
                     /locus_tag="KRH23_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224108.1"
                     /translation="MFKKMAVLKDIATKIGRKKAYELLEMVEGNDAFVAEVKIKKNGI
                     ESKKEEIMLKDNQKIILEYIEG"
     gene            95955..96683
                     /locus_tag="KRH23_000818"
     CDS             95955..96683
                     /locus_tag="KRH23_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHS5224109.1"
                     /translation="MLEIKNLSFNVESNNEELGIINDVSLSFERGKLIVITGPNGGGK
                     STIAKLIMGIEKATSGQIILDGEDITNLSITERAKKGIGYAFQQPPRIKGMTVENLLT
                     LAHGKPLSTDVCCQYLTDVGLCSKDYLNREVDNSLSGGEMKRIEIATLFARDLKVSIF
                     DEPEAGIDLWSFGKLNESFKKIHEESNQTIIIISHQERILELADEIIVLQDGSVKSHG
                     TKEAILPEIMCQVNSSCELMKDMN"
     gene            96705..97622
                     /locus_tag="KRH23_000819"
     CDS             96705..97622
                     /locus_tag="KRH23_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SufB/SufD family protein"
                     /protein_id="HHS5224110.1"
                     /translation="MNKIDLNLLEKVAELRGTPLGAYNIRKNGQGVERHSTENVTIIP
                     KTDKPGIDIIVKPNTKGENVHIPVIVTEAGVQDMVYNDFEIGENADVVIIAGCGIHNC
                     GCDDSEHNGIHRFFLRKGARLKYVEKHYGEGDGEGKRILNPVTIVNMDEDSYCEMETI
                     QIKGVDSTKREMDANLGKGAKIVVFEKLLTHGNQVAESNMKVILEGENSSAQVVSRTV
                     GQDNSKQKFNPCVIGDSLCSAHVQCDSIIMGNSQISAIPEIAANHPDALLVHEAAIGK
                     IAGDQILKMMTLGLTEEEAEQQILNCFLK"
     gene            97764..98948
                     /locus_tag="KRH23_000820"
     CDS             97764..98948
                     /locus_tag="KRH23_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HHS5224111.1"
                     /translation="MKNLLIRNGTIISPTDGIKFEKRDILVLHGKIYAIGLNLKEKIR
                     KEKLLTNKEFEIINADNMYISPGFIDVHTHCYKRKLPTGMDSDSIGIEKGSTVIFDAG
                     TAGPSNYYDFKKKYMDECKTEVYSFLNVTNEGLNILNESTSLDVINFDKVESIVEKNI
                     EKIKGIKVKASKFQSNESGIDIIKKSKQVAKKLNLPLVVYIGEYPSYIDEVMNILGKG
                     DVVTPVYGNSTNGILKESGTLRKSVINAKNRGVLFDVCHGVDQFDFKVFKKAIKQGLE
                     PDLISTDMHIKNMKDINYSLLNVINKIMELGISLEKCIEKVTEYPTKIFDLHGNKGRI
                     KIGGEGDFTIFTMEECNDIIKDYNNNELVLNKKLRLQYTVKSWMKSSEVYRHGYENTI
                     IN"
     gene            99055..99243
                     /locus_tag="KRH23_000821"
     CDS             99055..99243
                     /locus_tag="KRH23_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HHS5224112.1"
                     /translation="MKAFVDKDVCVACGACIGTCPDVFSMSDEGHSVAIEGEIPADLQ
                     DLCKEAEEGCPVSAITVK"
     gene            99392..100048
                     /locus_tag="KRH23_000822"
     CDS             99392..100048
                     /locus_tag="KRH23_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HHS5224113.1"
                     /translation="MKKNYEIVLFDLDGTLTDPKEGITKSIQYSLNSFGIKEDLENLD
                     QFIGPPLHDTFKEYYKFEDKKAKEAVEKYREYFADKGIFENKIYENMKEILEMLYKNG
                     KILLVATSKPTVFAETILRYFDIDRYFKYIAGSNLDGTRVNKNEVIQYVLDLCNVKDK
                     DKDKVIMVGDRKYDIIGAKKIGIDSIGVLYGYGSFEEISESEPTYIVENVESIKDILL
                     "
     gene            100151..101089
                     /locus_tag="KRH23_000823"
     CDS             100151..101089
                     /locus_tag="KRH23_000823"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HHS5224114.1"
                     /translation="MKSILIMGGSDFIGSALAKRLIKCGYQIDILTNGKKEIDYNGFK
                     EHLICDRKVRKDMENIITGRKYDYIYDMTAYTKEDVSNLIDFISMDNLKKYIVLSAGA
                     VYKDSGRNIKEENEKGENENWGKYGLNKKEAEDFIINSPIPYIIIRPTYIYGENNNLY
                     REYYFFEKIEKNEKIPVPKGKQVSNQFIYIGDLVKVLESIMKNPHVREAYNVTNPQLI
                     SWDDLIYTCGEIIGKEPIIKYVDMEKVEFRERTYFPFRNIDFNLDINKLIEHGLYIPN
                     VLLKEGLTATYKWFSANKPKMHDRKMNKVESVMQIV"
     gene            101211..101966
                     /locus_tag="KRH23_000824"
     CDS             101211..101966
                     /locus_tag="KRH23_000824"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0016311 - dephosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HHS5224115.1"
                     /translation="MKKYNISKNGALIKNDTIESKSESVKVVQISDTQIGSFYSTKNL
                     KKVANKINTLNPDIIVFTGDLIDYSNKSPSVDEITTILSSMNARLGKFSVFGNHDYMY
                     KLPRYYRQIMKNSNFNLLVNENKKIKLKDDKYINILGVDEILNGNPNIKYLESQIDNK
                     SFNLLLAHEPDLVDMLSKDTMNLVLSGHSHGGQIRLPIKGALVTPPYGRKYTKGFYDI
                     NGNHLYVSSGLGSTKLPFRFFNIPEIIEFNIII"
BASE COUNT        39935 a        11565 c        17379 g        33109 t
ORIGIN      
        1 atataaatta acctactgtt taattttcaa tgttcgtgtt tatttcttgt tccttttttc
       61 aaggacaagt aatactatac catctttaaa acagtaggtc aatacttttt ttatattttt
      121 ttataaattt ttttcatatt cttttttcag cttctctact acctttttct ctagtctaga
      181 aacagtcatc tgtgatatcc ctagttcttt agctatacta gattgtgttt tatcaaagaa
      241 aaatctatct ttaaaaattt taacttctaa ttcatttaaa gtttcaataa acttattaat
      301 aaaatcttca tactctatac ttccaaagtt accttcttct tttccaatct tatcaataag
      361 agttatatct ttatcctctg aatcatcatt acttgatgaa tccaaagaca ttggttgata
      421 tccataagaa gcctccatag cctctaaaac atcttcttca ctaacgccta tataatcagc
      481 tatatctttt acctttggat gcttcttatt ttcttgttct aatttaatct tcgcatcact
      541 tatctttttg cttaattcct gtattcttct tgggactcta agtgtccata ctttatctct
      601 aaaatacttt tttatttctc ctactatagt tggtgttgca aagctggaga actcaaatcc
      661 tttctcaaca tcatatctat caatagcata aattaatgcc aatgaagcaa cttgatatat
      721 atcttcaaaa tcaacacctt tgtttatata cttcttagct aacaatcttg ctaaatacag
      781 atgtctttca ataagaatat ttctaatgtc tacattttta tttttattat ataaattaaa
      841 tagctctttt gtatccatat ttaggtaatg tgtagcatta gctacatttt tcattaaata
      901 tcaactccta aatatttagt catttttatt tttgtccctt gattatgttc tgattcaata
      961 tctacatcat ccattaaagt tttaattata aacaatccaa gaccactctc ttttggattc
     1021 tctaaatctg gtgtacttat tgagctaaca tcatatcctt ttccattatc ttgaatttct
     1081 atattaattg cattatctaa aatattaaat actatattaa acacatcatc tttactgtgt
     1141 tttattgcat ttgtgcatgc ttcagatact gctaccttta tatcttctat atcatctatt
     1201 ggaaaaccca tcttattggc aattccagat gctgttaatc ttattatact aacataatct
     1261 ggatttgtag taatttccat ctttatagtc tcacaagcca aagtttatcc ctccacttta
     1321 aatattttat ctagacctgt tatagtaaaa atctttctta cgttactctt aggatttact
     1381 atgtatatct ctttttcatt tatttttaat ttttttaata cacctatcat agctcctaag
     1441 cctgttgagt ctatataatc taaatcttta agattaatct ttacatctaa catatttttt
     1501 tctattaaag catgtaaatg ttcctttagt ttatctgctg tagaaacatc aagttctcca
     1561 tcaagacaaa cattccaaaa tttattttgt gaatctaaat ttgaatcaat attcatagac
     1621 atgtaaaaac ctcctatttc cttttaataa ttttaaatat atttcctata ctcaatattt
     1681 tattaattac ataaactata tcatctattc cctttgatat tgatgatgca ttttcaacaa
     1741 tatcttgtat atgtctttca ttataatcta caatcttata tgccttttca acaaccttat
     1801 ttatgctgtt tagagtttta gctaaataaa ttgctactat aagagcagag cttcctacta
     1861 acactgctcc aatttgccac ccccatgcat tcattagtta acatctccct catcatcaaa
     1921 gcttttactt attactatat cttcttctga aatctttata tcttcttcat tattatcatc
     1981 atccactaaa tttattattc tctctttaac atcattaaat gtttcatgta gaacttcttt
     2041 tggattttct ttgacatcat taaacttctc ttttgtttct tttcttagtt cagaaccttt
     2101 tttaggtgca aaaaacatac caaatataaa ccctaaaata gctcctaata ataaaaatcc
     2161 acctttttta caacttcttt tattgcacat aacaattact cctttcaatt ttaaattttt
     2221 atctaactac attatacaaa aagaatagga tatttatcct attcttcttc aatatttatt
     2281 ttggcaatcg aaactacatt gacttcatca ttcgtcttca ttaatttaac accacttgta
     2341 actcttccaa acagtgatat ttcattgact cttattctaa taagaactcc atcagaattt
     2401 ataatcatta tctcatcatc ttcgttgacc atatctgcac ctacaattgt accagttttt
     2461 tcagatatat tataagtttt aattccttta ccagctctta tttgacttct atactcttct
     2521 atatttgttc tctttccaaa accattctta cttacaacta acacatctgt acctttactg
     2581 caaaggttca tagacacaac aaaatcttct ttacttaaag ttataccttt tacacccatt
     2641 gctgttctac ccatatatct tatatcattt tcatcaaatc ttatagacat accttcttta
     2701 gttactaaaa gtacttcttg ttttccatct gtaagttcta ctccaataag ctcatcatca
     2761 tctcttaaac ctattgcaat aagaccagat ttatttatat ttttgaactc ttctctctta
     2821 gtctttttaa caataccttt tttcgttgca agtaataaat attcattttc atcattacca
     2881 tcaataggta ttagagtagc aattttctca tctgctgaca attgaagtaa attcactata
     2941 gcagtacctt tagcctgtct cttaccttct ggtatttcat atgcatttaa tttaaatact
     3001 ctacctttat ttgtaaagaa taatagtcta ctatgagtag ttgtagttac caagtgcctt
     3061 acaaaatctt cttctctagt tgtaagtgct gaaatacctc ttccacccct tttttgactc
     3121 ttataagtat cagatggaag cctttttata tatccaaagt gagtaagagt tattgctatt
     3181 tcttcatcac ttataagatc tctcatatct atttcgcctt cagcatgtct tatttctgtt
     3241 cttctctcat cagagtaatt ttcttttatt attgtaattt catcctttat tacatttaaa
     3301 agtaatcttt catcagctaa aatctctttt aatctattta tcttcttgat taaatcttca
     3361 tattcagctt ctatcttatc tctttctaaa cctgtaagtc tttgaagtct catatctaat
     3421 atagcttgtg cttggatttc agttaatttg aatttttcta ttaaacctag cttagcttct
     3481 tgcccagtct ttgaagctct tatcaagctt ataacagcat ctatattatc taaagcaatc
     3541 tttaatcctt ctaaaatatg tgctcttgct tcagctttat ttagttcaaa tttagttctt
     3601 cttgtaacaa catcttcttg atgtttaata taatgatata atatttgttt aagatttaaa
     3661 actcttggct gaccatctac aagtgcaagc attattatac taaaagtatc ttccatttga
     3721 gaatgtttat acaaattatt taatactata ttagcattag catccctctt taattctata
     3781 acaattctca taccatttct attactttcg tctcttaggt ctgatatacc ttctattctc
     3841 ttttctttaa ctaactctgc tattctttca accagtttag ccttatttac ttgataaggt
     3901 atttctgtaa ctattatttg ctgttttcct tttggtagct cttctataaa agctctagac
     3961 ctaactttaa cttttcctct tccagttctg tatgcttctg ctatactttc ttttcccatt
     4021 ataattgcag ctgtagggaa atctggtcct tgaacaaatt ttattaaatc atctacacta
     4081 cactctggat tatctatcaa atatacagtt gcatcaatta cttctgctaa attatgtgga
     4141 ggtattgaag ttgccatacc aacagctata ccatttgagc catttactaa taaattagga
     4201 tatctagctg gcaatactga aggctctttt aacgactcat caaagtttgg tttaaagtct
     4261 acagtttcct tttcaatatc tctcagtagt tctaatgata atttactcat tttagcttct
     4321 gtataacgca tagcagctgg tgaatcccca tcaacagaac caaagttacc atgaccatct
     4381 actaaaagtg ctctagttga aaaatcttgt gccattctta ccatagcata ataaacagca
     4441 gtatctccat gaggatggta cttacctaaa acgtccccaa caatacgagc tgacttcctg
     4501 tatggtttat ctggagttaa atttaactca ctcattgaat ataatattct tctatgaact
     4561 ggctttaaac catctctaac atcaggaaga gcacgtccag ctataacact cattgaataa
     4621 tcaatatacg attttttcat ttcttccgct atttcaatag ggagtatttt gttattttct
     4681 tccatgtata ctaatcccct ctctctatat atctaagttt ctaacaaatc ttgcattttc
     4741 ttctataaat tcttttcttg gagcaacctt atcacccata agcattgaaa atacttcatc
     4801 tgcaattgca gcatcttcta cagtaacttg taataaagtt cttgtctcag gattcatagt
     4861 tgtttcccat aattgctctg cattcatctc tccaagacct ttgtaccttt gaagttcaac
     4921 accatttctt ccaatttcat ctagtaagat atttaactct ttatctgagt aaacataatg
     4981 ttccttcttt tgctttgtca ctttatataa aggtggctgt gctgcataaa catacccctc
     5041 atctataaga ggtctcatat atctaaagaa gaatgttaat aataaagttc ttatatgggc
     5101 tccgtctaca tcagcatcgg tcataattat aattttatga tacctagcct tatctatatc
     5161 aaaatcttct ccaataccac aaccataagc tgttatcata ttttttattt catctgaaga
     5221 tagtatccta tctagtcttg atttctcaac attaagtatt ttccctctta atggaagtat
     5281 agcttgacta tttctatctc taccttgttt agctgaacct cccgctgaat ccccttcgac
     5341 taagaatatt tcacttttag atggatcttt ttctgcacaa tctgcaagtt ttccaggtaa
     5401 agatgtactt tctaatacac tttttctcct tgttaattct cttgcttttt ttgcagcttc
     5461 tctagctctt tgtgctctta aagctttatc aactatgatt cttgctgttg atgggttttc
     5521 ttctaggaaa gaccccagtt catcaactgt tacactatca actatacctc tcataaagct
     5581 attacctagc tttgttttag tttgaccttc aaattgaggt tctggtaatt taactgatac
     5641 tactgctgta agaccttctc ttatgtcttc accaagtagg ttaacatcat tttcctttaa
     5701 aaatttattt ctcttagcat aatcatttac agttttagta agagctgctt taaatccact
     5761 taaatgagaa ccaccttcat gtgtatttat attgtttgca aaagaatata tgttctctgt
     5821 ataaccatct gtatattgca tagctagttc aacaaaacaa tcatcaacct ttttatctat
     5881 ataaactatg tcatcatgta taccagttct agatttattt aaatacttaa tgtattctac
     5941 caaaccacct gtatagtgaa attcttttct tttttcttgt ccttctcttt tatcttcaaa
     6001 tactattttt attcctttat tcaagaaaga aagttctcta agcctatact ccaatgtttc
     6061 atatttaaac tctatttcat caaatattgt ctcatctggc ataaattgaa tcattgttcc
     6121 tttatcttga gattctccaa ctacttcaag cttagatgtt ggcaatcctt tctcatatgt
     6181 ctgcttatat atctttccgt ttaaataaac ctctgctacc atccattttg acaatgcatt
     6241 aactacagaa acaccaactc catgaagacc tccagatact ttatatcctc cgcctccaaa
     6301 ctttcctcct gcatgaagat tagttaatac tgtttctaaa gttgatttac cagttttagg
     6361 atgtatttca acaggtatac ctcttccgtt atcttttact aaaacactgc catcttcatt
     6421 aatagataca tatatgtctg aacaatatcc ttgtaaagcc tcatctatac tattatctac
     6481 aacttcataa actaagtgat gtaaacctct agggcttgta ctaccaatat acatacctgg
     6541 tctttttcta acggcttcta atccctctaa tacttgtatc tgacttgcac cgtattcttg
     6601 tttcatttaa tttcctccat tctctatgct aataacatcg ccattttcaa tattaaatat
     6661 tgtaacattt ttttcatcaa atattttttt atgtgaaact tcagcacttg ttataaacat
     6721 ttgaacattg cttaaattat ttactaaaag tttttgtctt gcttcatcta actcactaaa
     6781 aacatcatct aaaattaata ctggatattc ttcaacttca ttttttatta attctatctc
     6841 tgataacttt aatgatattg aagcagttct ttgttgacct tgtgaaccaa aaagtcttgc
     6901 atctaaatca tttatgaata tatttaagtc atctttgtgt ataccatatc tggtagtctt
     6961 agattctata tcattaggtc tattcgatga caacttggct aaaaatttat tatatactgt
     7021 atctatagta tcttcatcag ttatatttat ttgattttta tatcgaattg ataatctttc
     7081 aactccatta gtcaaattca tatgcatatt ttcagatata ttagctatct tttttataaa
     7141 gtctctacgc aaaatataaa tataacttcc atactttgct aacgtatcat catatacatc
     7201 taataaagct tcatcaacat gtatattttt aagcacccta ctcctttgag aaagtgtttt
     7261 attataattg gtaagatatt tataatattt aggtataatc tgactaatct ctttgtctat
     7321 aaatgccctt ctttctttag gaccctcttt aaccaacctt aaatcctcag gagaaaatat
     7381 aacaacattt aagttgccaa gtagttcttg tatcttttgt aaaggaactt tatttattct
     7441 tatccctttt ttatcttttc caataattag ctctattaga ctatatttat tatattttga
     7501 aaaacttcct ccaatatata agttttcact attaaatcta accatttctt tatctttgtt
     7561 agtcctaaat gattttccaa aagaaagcat ataaatagat tctactatat ttgtctttcc
     7621 ttgaccattt ttaccaacaa gtagatttac tttcccatta aattccagat gcaacttttt
     7681 ataatttcta aaattaacaa gttgcaaact tttaagtttc acaaaaagtt ctcctttttt
     7741 acaatacttt tattttagtt ccttctattt caactatatc tcctgatttt atcttttttc
     7801 ctcttcttaa ttctatttca tcatttactg tcactaaacc ttcttgaatt aaaaattttg
     7861 catgacctcc tgttgatgca atctctgcta atttaagaaa ttgatccaac tttatatatt
     7921 ctgattctat agttatttca gtcataatag ttcctccttg tcactatttt aaacaaattc
     7981 ctattgatac actaaaagta tattatacca taaatatgct tataaaagga gttgtctaag
     8041 attagaaaaa ttttctacaa aagacaactc cttcatgtct gctatatatt tgatgatatt
     8101 cttactggaa gcagtaagta aatataatta acatcatctg ttggtttaat tatacaagga
     8161 tttacatttg tagtaaattc tataaatatt tcctcattat ctatattttt caaaccttcg
     8221 ataaaatatc tagaattgaa agctatatct aggtaatctc catctaaatc tatttcaact
     8281 tcttcataca catttccttt ttctgtatta gaagtaattg ccattacttt atctcttata
     8341 gataacttta taagattatt tttttctgat tgagacaata aagacgctct ctctatacta
     8401 tttaaaagtt ccttagtatt taatttaact ctgctgttat gttctcttgg caataatttt
     8461 ttataatcaa taaaatctcc ttcaagcaat cttgtaataa ttttcgtatc attaattata
     8521 aaaatagcat ttttttcgtt aaatccaact ttaacattat cctctccaga aagcaaacta
     8581 tttacatcta taagtgtctt tccaggaatt atgactttta tattttcagt taaactatca
     8641 accgaacaac tttttacagc taatctatat ccatcaattg ctactaaatt taagtttcta
     8701 tctacaattt ctaaaagttc tcccattaaa acaggttttg tttggtcctg tgagatagca
     8761 aatacagttt gtttaatcat attttttagg atttcttgag gtatgctata taaatcttct
     8821 tcatttaatt ctggtaattt aggaaattct tttgctgcat aacctttaat tttaaatctt
     8881 gaatttacac aatttatgta aatattattt tctgaatcag tttctatctc aacaaaggaa
     8941 tctggtaatt ttctaattat atctccaaat agccttgcat ctacaacaac atcacctttt
     9001 tctatgattt ctgcttgtac ataagtttct attcctattt cagcatcata tccagtaagt
     9061 tttaattgac cttcttctgt agatataagt atacctttta ataattctat tgttgttttt
     9121 ccattaatag ctttttgagc aattccaatt ctatttgcta ggattttttg attacaaatt
     9181 attttcaatg tggataacct cctctggctt tttatatata aaaataagtt aaaatcatag
     9241 tagtaatagt agtaggtgtt gttgataatg ttaataagta tgtataacat tataaataca
     9301 aagatattaa catgtgtata agatgttaat atctttgtta ttttagactt gataatttgt
     9361 taataatttt tgttcaaaaa aagtattaac aggttattca agagatataa acatacaatt
     9421 gtgtataaat tatcccttca aatctgatat aattttgtct attttagtct taatttcttc
     9481 actttcttct atatccttag atactttgtc atgagcatga attactgttg tatggtctct
     9541 acccccaaac tcttcaccta ttttaggaag ggataaatca gtaagctcgc gcgttaaata
     9601 catagctatc tgtcttggat aagctattga acgtgttctt tttttagaat taaaatcttc
     9661 catctttaaa ttgaatacag aagatacttt ttcttttatt ctgagaacat ttatttcttc
     9721 atttttagaa gttgttataa tatcttttaa agcttctgta gcaagatcaa aagatattac
     9781 cctattgcta agagaagaat aagcaaccac tctagttaat gcaccttcta gttcccttat
     9841 gtttgactta atattttttg ctatatatga cataacctca tttggcacat ctatacgttc
     9901 tagttgagcc ttttttctaa gtatagcaat tcttgtctca aagtcaggtg cttgaatatc
     9961 agttataagt cccatttcaa atctcgatct tagcctatct tctagtgtag gtatgtcttt
    10021 tggcggtcta tcactagata taattatttg tttgtttgct tcatgaagag tattgaatgt
    10081 atggaaaaac tcttcttgag ttctttcttt tcctgctata aattgaatat cgtcgattag
    10141 taatacatct acgtttctat atttattcct aaattcttcg tttttatcgt cttttataga
    10201 gtttataagt tcattagtaa atttttctga agaaacgtaa actacttttg agtctttttt
    10261 ttgactaaca atatgatgac ctatagcatg cattaggtga gtcttaccta atccaactcc
    10321 tccatacaaa aaaagtgggt tataagcttt agctggagat tctgcaactg caacgcatgc
    10381 agcatgtgca aatctattac tattaccaat aacgaatgta tcaaatgtgt attttggatt
    10441 tagattgggg taaagaactc tataatttaa atctgtgcta tcagaattta aatcagcaac
    10501 ctctttttcg ctcaatacaa atttaatatt atattttttt aatgacagtt gactaatagc
    10561 atcttcaatt aaatgtaaat atctattctc taagatatct ttattaaaat cactaggagc
    10621 cagtaagatt aaatcattaa gatgtatttt taatggtacg atgtttttaa aaaaggtatt
    10681 aaaacttact gaagttaagt caccttttat taattgtagg gttttgtccc ataaagaaac
    10741 tatatccata atataaacct ccgaacagaa taattaatat tttccacaaa gttattaaca
    10801 gaaaagcaaa aatatatata aattttacag aataactaaa tttatggata atggtgttga
    10861 taaattaata atagtataaa ttattaaaaa aatatgaaaa gatataaaca atatgtagat
    10921 aaagttataa ataacataaa catacaataa atggtgatta taactagagt attgtcagta
    10981 atcttaaaag ttatacacaa aagtatccac aagctgtgaa taatttctaa taagttgata
    11041 acatttatgc acattatcaa caagtatatt tataatatca aaatatatgt caaacttcaa
    11101 tgatttgtaa ctaatttatc cacaatatta actaattgtt gataaaaata taaacatgtt
    11161 aaaattactt tatttgtgta tataattgaa aaaaataatt tagaataaaa ttaaatagat
    11221 ttttactagt attttcaata aaaaaaatac ataatatata tatggtagat tttgtgatat
    11281 aagcgtccca aaaactcgtt gacaacagta gtaaaagtat ttataattat atgtgttatg
    11341 tttactttga gggtaaagtt attattttta taaacggaaa ataaaatctg aaaggcggtg
    11401 caaaataatg agtaaaagaa cttatcaacc aaaaaagaga caaagaagta aagaacatgg
    11461 tttcagaaaa agaatgaaga cgtctaacgg aagaaacgtg ttaaagagaa gaagagctaa
    11521 aggaagaaat agattaactc attaattaca aaagggccgc tgcaaaggtg gcctttttgt
    11581 gtaaataatt acaattcata gctgtgttta tggaggttaa ctatggactt taataggact
    11641 aaagggttga aaaaagactc tgattttaga aaagtatata aacacggcaa atcttttgca
    11701 aacaaatatt tagtaatata tatacttaaa aataaatcag attatagtag agtaggtatt
    11761 tctgtttcaa aaaaagtagg aaaagctatt actaggaata gagtaagaag attaataaaa
    11821 gaagcctaca gattaaatat tgatgaaaaa attaagcctg gatatgatat agtatttata
    11881 gcaagggtat ctagtaagga tgctactttt aaagacatag acaagtctat aaaaaattta
    11941 gttaaaagaa cggatatttc tatttaattg tatgctataa atatggaggt taatgacttt
    12001 gaataaaata atttatatat taaaggaaat aagtaagtat ttatcgaatt tatgtattta
    12061 tttagtgaga ttttatcaaa agtatatatc tcccttaaag ggacctacct gtagatttta
    12121 tccaacttgc tcacaatatt caatagaggc gtttaagaaa tatggatttg taaaaggtat
    12181 gtatttaacg ataagaagac ttttaaaatg tcatcctttt catccaggag gttacgaccc
    12241 tctaaaataa aagagagtaa ctattaggag gtataaaaaa attgaatata ataggaaatt
    12301 tcttaggatt gattcttaag gtaatatttg aatttgttaa tcattatggt atttctataa
    12361 tactttttac gatacttgta aagattattt tattaccatt aacaattaag cagactaagt
    12421 caacaaaggc aatgcaagat atacaacctc gtataaaaga gatacaagaa aaatataaaa
    12481 ataagccaga aaaacaaaat gaagaaattg ttaagttata tggagaagct aaaattaatc
    12541 cactatctgg ttgtttacct ttattaatac agtttcctat attaatagga ttatttagcg
    12601 ttttgagaga accagttgct catggcgttt ttgcaaacaa agctgcattt ttagcagctg
    12661 acaatgggtt tttatggata aaaagcttaa catcaccaga ttatgtatta gcagtatttt
    12721 caggagcaag tgcatatgtc atgcaaaaag taatgacacc aaaagatcag ttacaaggct
    12781 ctatgaaagt aatgacatat gtaatggcag gtatgtcttt ctattgggga tttatattcc
    12841 cagcaggact tacattgtac tggacagtaa gtaacttatt ctcaatagct caatattact
    12901 taataatgaa tcctttaaaa gctaaactgg ctgctaactc taaggaggaa aaagttaatg
    12961 agaaaaagcc taaaattaat aaaaagtaag agtaaagagg aagctataag taaagctata
    13021 gcagagttga atttaaaagc agaggatata gaagtagaaa tacttgaaaa tccaagtaaa
    13081 gggtttttag gttttatagg tgctaaagat ggtacttatg aaatttttgt tatcgagagg
    13141 gaagtagatg tagctaaaaa ttttatagag gtaatgttga aaaatgcaaa tgttgatgcc
    13201 aaagtcaatg tatctcaaaa agataattta atcatggttg atattgaagg caaagaagct
    13261 gcaagtttaa ttggtagaag aggggaaact ttagattcta ttcaattttt gactggatta
    13321 gctcttaata aaataaataa agattctcat acaagagtac ttgtagatat agaaaattat
    13381 agatcaaaac gagaagaatc tttaataaga tatgctaata aagttgctag agaagtagcg
    13441 aaaacaagaa aaactaaaaa attagattat atgaatccat atgagagaag aataatacat
    13501 tcagctcttc aaaatgacaa atatgtaatt acatatagtg aaggaaccga tccatataga
    13561 agattagtaa ttgagtgtaa aagataaagt caacctccta aacattaggg ggttttattt
    13621 tttaatatta ttaaatcatt aatgattggt taaatgtaaa tctatatgta aaaaattatg
    13681 aattaagagg tgataaattt gtttatagat gatacaattg cagcaatagc tacagcacct
    13741 ggagaaggtg gtataggtat acttagaata agtggagaaa aagctttgaa ggttgcagaa
    13801 gaaatcttta aatctatgtc tggaaagagt attgaagaat acaataagag aacattaata
    13861 tatggaaata tagtggataa tgaaaatata attgatgaag ttttattggc atatatgaaa
    13921 ggaccaaatt cctatacagg agaagatgtt atagaaatta attgccatgg tggatttatt
    13981 tcggtaaaga agatattaga attaatacta tcaaaagatg ttagattagc agaggctggt
    14041 gagtttacta aaagagcatt cttaaatgga agaatagatt tatctcaagc agaggctgta
    14101 attgatgtta taaaagccaa aactgatata gctcatgaag ttgctcaaaa tcaattagaa
    14161 ggttctttat caaagaagat aagagaattg agagataaag tcactgagat attagctcat
    14221 gtagaagttg ctatagatta tcctgaggaa gatattgagc atataacata tcaaactctt
    14281 aaagaaaaaa ctgatgaact taaaaaagac attaaaaaat tatatgatac agctgaaagt
    14341 ggaaaaatac ttagagaagg cttaaagacg gtaattgttg ggaaaccaaa tgtaggtaaa
    14401 tcttcactac ttaattctat tttaggagag aatagagcaa tagttactga tataccagga
    14461 actactagag atgttataga agagtttgta aacataaaag gtataccttt aaaaattgtt
    14521 gacacagcag gtataagaga tactgatgat attgttgaaa aaataggtgt tgaaaagtct
    14581 aaagaatcat ttactagtgc agatttgata gtaatggttt tagatgcatc tagaaagttg
    14641 tcagaagaag atatagagat attagaaaaa cttaaggata aacaaacaat agtgctgtta
    14701 aataagaatg atttgaaaca agagattgaa gaagaaaaaa tacttaaata tgtagaaaat
    14761 aatagtataa taaaaatatc agctttacaa caagaaggaa tagaagaatt gcaagataaa
    14821 atagagtcta tggtatataa aggtagtatc aaaaataatt ctagtttagt agtaacaaat
    14881 tcaagacata aagatgcact tagtaaagca tataaatctg caacagatgc tttaattgct
    14941 ttggaacaaa gtatgccatt tgactttgta gaagtcgatt taaaaaatat atgggactat
    15001 cttggatata ttaatggtga tacagtaaca gaggatttac tagataatat attccataat
    15061 ttctgtattg gtaagtaatg tacaaaagta aacttgtttt tattatagag atttttaaaa
    15121 aatttgaagt gtttctcatg aaacattaat tttgaaaaga aaggaattat aaatgataaa
    15181 gtttgaagca ggaaaatatg atgttatagt agtcggagca ggacatgctg gatgtgaagc
    15241 tgctttggct actgcaagaa tgggatataa aactttgata ataacaatgt ctttggattc
    15301 catagcatta atgccttgta atccatcaat tggagggact ggtaaaggtc aattagttaa
    15361 agaaatagat gccttaggcg gtcagatggg attaaatata gacaagacat atatacaaag
    15421 tagaatgtta aatactgcca aaggtccagc ggtacactct ttaagagcac aagcagataa
    15481 atttaaatat catgaagaaa tgaaaaagac attagaagat gaaccaaatc ttgatatagc
    15541 tatggatgaa gttgtagaaa tacttcatga aggaaatgtt gtaataggag ttggaactaa
    15601 actaggatgt tcatttaaat ctaaagctgt aatattggcc actggagttt atctgaactc
    15661 aaagatatat atgggtgaag ttgcatttta tgaaggtcct aatgcattgg ggtatgcaaa
    15721 atatcttaca gatagcttag ttgagcttgg tcttagaatg agaagattta agacgggaac
    15781 tccagcaaga gttcatagag atagtataga cttctctgta atgtctttac aagagggcga
    15841 tgaaaaagta actccattct catttatgaa tgaaaatata gaaaaaaaac aagaaccttg
    15901 ttatttaacc agaactacag aagaaactca aaaagttata ctggataatt taaaaaggtc
    15961 tgctatgtat agtggagtaa tagaaagtac tggtccaaga tactgtcctt ctatagaaga
    16021 taaagtagta cgatttagtg ataaaacatc acatcaatta tttatagaac cagaagggtt
    16081 aaatactaaa gaaatgtata tacaaggaat ttcaactagt ttaccttttg aagttcaatt
    16141 agatatgtac aaaactataa agggacttga aaattgtaag ataatgagac ctgcatatgc
    16201 tattgaatat gattgtgttg acccaactca actaaaaata agtttggaaa taaagggtgt
    16261 tgagaactta tttagtgcag ggcaatttaa tggaacttct ggatacgagg aagcagcagc
    16321 tcaagggctt atggctggta taaatgcagt tagaaagata gaaggaaaag agccatttgt
    16381 attagaccgt tcagaagctt atataggtgt cttattagat gaccttgtta ctaaaggaac
    16441 taacgagcct tacagaatga tgacatcaag agcagaatat cgactatatt taagacaaga
    16501 taatgcagat atgagattaa ctcaaaaagg ttatgatata ggattagtta aaaaagatag
    16561 atatgaaagg ttcctaaata aaaaggctgc tgtagagaaa gaatttgaaa gactaaaaaa
    16621 tgaaagagtt acaccaaaag aagtaaatag tttgttggaa gaaaaaggag caacaccaat
    16681 aaaggttgga atatctctat atgaattttt aaagagacca gaggttactt acgaattgct
    16741 tgaagaatta gggaaaggcg ctggagaaga tgtttcaaga gaagttaaag aacagtgtgt
    16801 aataataact aaatatgaag gttatataga gaaacaattg aaacaaatag accaatttaa
    16861 aaaacttgag aataaaaagc tggatgagaa aataaattat tcatctatag aaggtcttag
    16921 attagaagct agacagaaat tagatgatat aaaacctatt tcaatagggc aagcatctcg
    16981 tatatctggt gtttctccag ctgatatatc agttttactt atatacctag aacaaatcag
    17041 aagaactaga ggtggcaaag gtgaataata tagaacttct gaaaaacggg attgaaggtt
    17101 ttaatataga tacgaatgac agtatgttag aaaaatttaa aatctataga gagatattag
    17161 ttgaatggaa taaaaagatg aatcttactg gaatagaaga tgaaaaagaa gtgtatataa
    17221 aacatttttt agactctatt tcagctgtaa agaatggata tataaaaaat gggatgtcta
    17281 taatagatgt tggtacaggt gctggttttc ctggaatacc attgaaaata tgtttagata
    17341 gcttagaact tactttgtta gattcgttaa ataaaagaat aaacttttta gaggaagtta
    17401 gtagagtact agagttagat aatattacat ttatacatgg aagagctgaa gattttggta
    17461 aaaatgaaga ctatagggaa aaatatgatg ttgctacggc aagagctgtt gctggattac
    17521 cgattcttat ggaattttgt gtaccatttg taaaagttgg agggtatttt atttgcttaa
    17581 aaggtccaaa tgctaattta gagctagaag aatcacaaaa ggctattgat gttttaggat
    17641 tggagtatat tgaaaaaata gatgtagagt taccagaggt agatttaaat cataatatat
    17701 tagtttttaa aaaagtgatg gaaacaccag ttaagtaccc tagaaaagct ggtaaaccag
    17761 ccaaaaatcc tattaagtaa tgaaaaattt attattggta agcttaatta tttctcagga
    17821 aataattaag cttactgtaa aaaaacaaaa ataaaggaat tattaaagta gatgcagaaa
    17881 taaatttgta tgtacatata gagaacaaaa ataatttata tctaaaataa gagaggtatg
    17941 ttatggaaga taaaagagtt atggagatac ctatagaaga tgtagttcca aatccatatc
    18001 aaccaagaaa aatattttca caagtttcat tggaggaatt gagcaattct ataaaggtat
    18061 atggtataat tcaacctata acagttagag caaaagatgg caaatatgaa ctaattgcag
    18121 gagaaagaag attaagagca gctaaattag cagagcttaa aaccatacca gcaattataa
    18181 ataatatgaa cgatgaatct tctgctgttc tagcgttatt agaaaatttg caacgagaag
    18241 acttaaattt cattgaagaa gcaattggtt atgaaaactt aataaaagaa catgctttta
    18301 ctcaacagca attagcagaa aaattgggca aaaatcaatc tactgtagca aataagctta
    18361 gaatattaaa gcttccaaac gatataaaaa tgaagctaat agagaataat ttaacagaaa
    18421 gacatgctag agcatttctt aaactaccaa gtgaagattt aatgcaaagt gtgttagaca
    18481 aagtcataaa aaatgaattg actgttaaaa aaacagaaaa attgatacaa gatgtattag
    18541 aagaaactaa agttcaagaa gagcctgata aaaaacagaa tataaagggt gctatgagta
    18601 taagaattta cataaatact ataaagcagg cctttgatgc tatatcaaat acaggaattg
    18661 atgctaagta taatgaaata gataagggag attatatgga agttgttgta aaaatcccta
    18721 aaaaatagag attactgctt accagtaatc tttttttgta atataagcct tgtaatataa
    18781 actgatttat agacattatt tatacttaaa aaacacctat tcaacattta aaattaattt
    18841 aattcttaaa ggggggaaca tcatgggcaa agttatagct gtattcaatc aaaagggtgg
    18901 agtcgggaaa actacaacaa atgtaaattt aagtgctagc ttaggaactt tgggaaagaa
    18961 aatattagta ttagatttag acccacaagg aaatacaact agtggatatg gtattaataa
    19021 aaacgaagta gaaaatacaa tctatgaaat tatgttagat gggttacata ttaaagaagc
    19081 aataataagt actgaatttg agaatataga tgtagttcca tcagctactg aactatcagg
    19141 tgcagagata gagcttacat ctaaaactaa tagagagtat attttaaaaa attccataaa
    19201 agcggtaata gatgaatatg attatatatt tttagattgt ccaccctcac tggggatgct
    19261 tacaataaat tgtttaactg ctgtagatag tgttttaatt ccaatacaat gtgaatatta
    19321 tgctttagaa ggtgttagtc aattaatgga gactataaaa ttagtaaaat caagattaaa
    19381 tgctgatata gaaattcaag gtgttgtttt aagtatgttt gatggaagag ctaatttatc
    19441 aatacaagta gttgaagaag ttaagaaata ctttaaaggt agtgtatata caactttaat
    19501 tccaagaaat gtaagacttg cagaagctcc aagtcatgga aaacctgtaa tttattatga
    19561 taaaagatgt agagggtctg tagcttattt ggagctagca gaagaattta tagatttaga
    19621 agaggaggaa tggtagtatg gagaataagt ctaaaagaag taatagatta ggtagaggtc
    19681 ttagtgcatt gataccagaa attaaaggag aaacttcaga aaaagaaata gtcaacatag
    19741 atatagacaa aatatatcca aacgaagttc aacctagaaa gcaatttgat gaagaaaaga
    19801 taaaagtatt gtcggactct ataaaaaatt atggtgtttt acagccaata gtggttaaaa
    19861 tggatgaaaa taataaatat atgataatag ctggagaaag aagatttaga gcatcaaaac
    19921 ttgcaaataa aaatcaaata cctgctataa ttaaagatat agatatgaaa gatataatgg
    19981 agatagcctt aattgaaaac ttacagaggg aagatttaaa ttcaatagaa gaggctctag
    20041 catataagag tttaatagag cattacaatg taactcagga agaaatatca gaagctgttg
    20101 ggaagagtag acctcatata actaatacac taagactttt aaatcttgga caagatgtta
    20161 tagaaatgat agacagtggt agaatcacag caggccatgg taaggcttta ttgagaattg
    20221 cagataaaga tttgcaactt caaatagcga aaaaaataga agaagaagaa ctttctgtaa
    20281 gagaagtcga aaatatagct aaaaaaatat ctgaaaataa acaagaagaa cctaaaaaat
    20341 ctaaacctaa ggatgtattt attttagatg ttgaagataa acttagaaat atatttggaa
    20401 caaaggtgaa tatttctaaa ggaaagaaaa aaggtaaaat agagatagaa tactataatg
    20461 atgatgattt aaatagtatt gtatcaatgc ttcttgaata gaacaaaaat ataaaacaga
    20521 gaggaagatt gttatgattt atttagataa tgctgcaact acatatccaa aaccagaaag
    20581 agtgtataat gctgttttag attgtatgaa aaattattgt gcaaatccag gtagagcagg
    20641 ccataaactt gctatgagag ctgctaggga gatatatgat acaagagaga atatagctaa
    20701 gttgttcaat gtaagtaatc ctatgaatat agtatttaca tctaatgcaa cagattcttt
    20761 aaatttagcg ataaaaggtg tattacaaga aggagaccat gtaataacaa cgtctatgga
    20821 gcataattca gtaataagac ctataaaagc attggaaaaa aggggtattg aaaatactgt
    20881 agtaaaatgc gattatgagg gatttttaga ttatgaagat ttagaaaaat caataaagaa
    20941 taatactaaa ttgattgtaa caacacatgc gtctaatgta tgtggaactt taatagatat
    21001 aaaaaaagtt ggagaaatag ctaaaaaaca taatatacta tttttagtag atgcatcaca
    21061 aacagcaggt gtttatgata tagacgtaaa tgaatgtaat atagatatgt tggcaatgcc
    21121 aggtcataaa tgcttatttg gacctcaagg aacaggtata ttatatgtaa gagaagggtt
    21181 gaacttaaat atattaaaag aaggtggaac aggtagtaaa tcagaagaaa tagttcaacc
    21241 agagttattc ccagataaat atgaatcagg aactcataat actccaggta tagcaggtct
    21301 taaccaaggt atactattta tatttgaaag aggaatcaac aatataagac aacatgaaga
    21361 agaattatgt caatatatga tagacaaatt agaggaagta ccagatataa agatatatgg
    21421 accaaaggac agtaaaaaaa gagcatcagt aatagctcta aatataggag atatggattc
    21481 tggagaggtt actttcttat tagatagtga ttataatata gcgactagat caggaataca
    21541 ttgttcacca ctagcacata ccactttagg tactttaaaa caaggtgcag taaggttcag
    21601 tataggatat ttcaacacaa aagatgagat agataaagca gtggaagctt tgaaaaaaat
    21661 ttcaaaaaat aaatagcatg agatttaata atatagaaat aaaaaagggg atatttcaaa
    21721 ataaaaattt gaatcatctc cttttttgta caaaaaagaa aaggggtccc taagaacctc
    21781 taatctattt gataattgtt ttaagaagtt actttaagta atctccttct tcaagaacta
    21841 tatgaccact ttcgtaatta gaaccatcaa cagtaatttt tatttgttca acattcatat
    21901 tttttatgta agtacgagca actgaatcaa gcattaaagt ttctgcatca ctacctaagt
    21961 ttgactttgt aaagtcagag ctaacatcta atataccagt ttttacacca tcaatgtctt
    22021 ttgtagtaaa tgaatttaat tttgcagatt ctggaacaac tttaagtttt tgaagttctt
    22081 caaataaagt gttctcatca attttattta aatcaacttt attttcaatt aaatctgtct
    22141 tatctacatc aaaagagtaa atagtagctg attgagtttt agtttcttct tttggagtag
    22201 gtttagtttt gttattagga acctcttttt cagtattgtt ttcttctttt ggttgctcaa
    22261 catttgtatt gctcttagtt tcttttttag atgaatcact tccattttga gcattagtac
    22321 aaccaactgc gaatatagat atagataata tacttaacac taacattatt ttcttatttt
    22381 tcataaaaat ttctcctctc ttaaaaacta ttcttatata taattatagt cgttatgagc
    22441 aaatatatga atacaaaata gtaacaaatt taaaaaatga tttatttaaa ttaataaaac
    22501 tcaaaataaa ctaaatttta gtcattttta tgggaaatca tttaatgtac agtgaaaata
    22561 ttgtaaaata aaagtagtgt ttttaaaata aatataagtt ataattatat tataaaaaaa
    22621 tgtcttcaaa aggtgggaat agtatggaaa ttttgagctt aggagaaaag attaaaaaat
    22681 taagaaaaga aaaaaacatg acattaaaag aattagctgg agataggata acagcagcac
    22741 aaataagcca tatagagagg gataaatctc atactagtta tgaactgttg gaatatctag
    22801 gcgataagct agatgtaagt gtagaatact tattagagac caaggaaatg caatcaaaaa
    22861 agataactga taatttaata ctacagagcg aaatttatat aaaagaaaat gaattaaaca
    22921 aggctgagga ccaaataaaa gaagttttag atatatgtaa gagatacgat ttaatggaga
    22981 actatggcag atgtaatttt ttaatggcta atattaattt gaaaaaatct aattataatg
    23041 atgctataga aaactttgaa aaggcattgt acttctttat aaaaaatagt gatagtgaaa
    23101 atatacttaa gtgttattta aacataggga aaatatatat gcaggaagac ttttataaag
    23161 gtgctataag ccactttaat tttgcagagg aaattttgtc agagagtaaa tttgaggatg
    23221 ttaacataca caaggaacta tatagtaaga tggcatattg ttacataaaa ctagataatc
    23281 caaatatgtc attgaagtac atagaaaaga taaatgaaat agataataga aatgatagaa
    23341 aagaagatgt cgatattttg gtgttaaaag caaataatat gcttgagatt ggaaaatatg
    23401 aagaatcaag agattacttt aaaaaagcac taaaaatact tgagagtgag gataataaaa
    23461 ctggattagc aaatgtgtat ttaacaattt gtgatgttta cagaaaaata ggtgaaacag
    23521 atagagtact tgaatattca caaaaggtat atgacataaa gaaaaatgat gaagatgaat
    23581 acatgatgtc aggattattt aagataatag aagcatatat agataaagaa gattatgatt
    23641 tagctagaaa atattgtaag atagccttag cttcatcaat aaaaaataaa aataaattca
    23701 atgaatataa agcattgaga ttctatgcta atatgtataa aaatcagaat gaagtaactc
    23761 ttgcaattga atatctgatt aaatgcataa aaatagtatc agatttaggc aacaatagaa
    23821 tattggccaa tttatatata gacttaggtc aattatattc aaatatatca aaagaaaaag
    23881 agttagaata ttatcaaaaa ggtgtattta tgtacaaaaa tttagaaata atgtagggta
    23941 aataaaccta taagggtata gaaacaatct ataacaagca agataatatc tatgataaaa
    24001 tataaattgt atgaatattt ttaaggagat gaatcagaca atgagtataa aaatagatgc
    24061 gagagggctt gcttgtccta aaccagttat aaatacaaaa agagaattgg ataacctaga
    24121 agaaggtgtt gtagttacaa tagttgataa tgaaacagct aaggataata tattaaaact
    24181 tgctaaatct ttaagttgtg aagcaaatat tgttgacgaa aaagagaatt ttatatctat
    24241 agaaattaga aaaggtaaaa atatactaga taaacaaaat gttgtagata ataaagaaag
    24301 tgaattagac aatacatgta tatttatatc ttcagataag atgggacttg gaaatgacga
    24361 attaggaaaa gtgttaataa aaggatttat atatacatta acagaatcta aaccttatcc
    24421 taagtatgta cttttagtta atggaggagt aaaattaagt gctgaaaatg aagaaaccat
    24481 agaaaatcta aaaatacttg agaatatggg tgtagaagtt ttatcttgtg gtacttgttt
    24541 agattattat aatttaaaag acaaattaca agtaggtaca gttacaaata tgtatactat
    24601 agttgagaca ttaaagaatg catcaaatac catttctata taatgtatgt atgtttaata
    24661 atataaaact aacaataaag attaactcaa atagatagtc agaaaggatt aagtaatgaa
    24721 tcaaatgtat atagtgtcat ttaattcgac acatcatgcg ataagatcag aaaagttatt
    24781 tggtgaaaat agtctaaaag taatggctct tccaacacca agagaaataa cagcaagttg
    24841 tggaatatca attaaatttt cttttgaaga tatggaaaag ataaaaacta ttttggttga
    24901 aaataatgta gatataaaag gaatttattg tataagtaaa ttagaaaatg gttcaaaaga
    24961 agtagagaag ttagattagg aggctaatta tttatgccaa tggatttaaa aataggtgat
    25021 attgttgaat taaaaaagca acatgcatgt gggtgtaaag agtttgaaat cataagaacg
    25081 ggaatggata taaagataaa atgtactaaa tgttcaaggc taataatgct tgatagagag
    25141 accttagaaa agagagtaaa aaagctaata aaaaagtgat aaaaatttaa cacttaaaaa
    25201 atgtcaaata ccgtatatta atatccaaaa ttttggtata ataagaattg aagaaaacat
    25261 tttcatgggg gtgctttaat tatggcagtt aaatatgcaa aaagaatgca aggattacaa
    25321 ggatcagaaa tacgtgagct tttaaaactt actcaacaac cacaaataat atcttttgct
    25381 ggtggaatgc cggctccaga gttatttcca gttgaggaaa tgaaaaaagt atcagttgca
    25441 gtgcttgaag aaaatggaag atcagctatg caatatacta caacagaagg atatgaacca
    25501 ttaagagaaa aaatagcagc tagaatgaat gataaaaaca aaactaatgt aaacaaagat
    25561 gatatattag ttacaagtgg ttctcaacaa ggtctagatt ttgcaggaaa agtatttatt
    25621 gatgagggtg atgtaatttt atgtgaaagt ccatcttaca taggagctat aaacgcattt
    25681 aaatcttatc aacctaaatt catagatgtt ccaacagatt ctgatggaat gataatggaa
    25741 gaattagaaa agatactaga aacaactgat agaataaaaa tgatttacgt aatacctgac
    25801 ttccaaaatc caacaggaag aacttggcca cttgaaagac gtaaaaaatt catggaaata
    25861 gtaaataaat ttgaaatacc agtaatagaa gataatccat atggagattt aagatttgaa
    25921 ggagagactt taccatcttt aaaatcaatg gatacaaaag gattagtaat attcttagga
    25981 actttctcta aaatattctg cccaggatac agattaggat ggacttgtgc ttctccagaa
    26041 attttatcta agtttaactt tgcaaaacaa ggtgcagact tacaagcatc aactatatct
    26101 caaatggaag taagcaaatt tatggatatg tatgacctag atgcacatgt tgacaaaata
    26161 aaagcagttt atgttaaacg tagagatgta atgcttaaga ctatggaaga agagttccca
    26221 gaaggattag tatttactca tccagaaggt ggattattta catgggtaga gcttccaagt
    26281 aatttaaatg ctaaagaatt aatgccaaaa tgtttagata agaatgttgc ttatgttgct
    26341 ggaggaggat tcttccctaa tggtggtaga gaaaatactt tcagacttaa ctattcaaat
    26401 atgccagaag aaaaaataat agaaggtata aaaaatatag cagctgtatt aaaagaagct
    26461 atgggtgtag aagcttaatt aaaaataata acttatatat aatacaaggg atggttgttg
    26521 ccatcccttg tttgtttgaa aagtatataa ttcaccttat actaaacttt gtccaaaatt
    26581 taaattgaca gaaataagaa taaatgataa aatgtgtagg tatgagattt tagtctcatt
    26641 tctctgctct aagagtgtag agccgttaag tccaaaggga ggtgaattat agtgagaaat
    26701 tatgaattag tttatgtggt aaagccaaac tctgatgaag aagtaagaga ggctatacta
    26761 aacaaagtta aggaagttgt tgcaactgac ggagaaatag ttaaagttga tacttgggga
    26821 actaaaaaat tagcttatcc aatagctaag tttacagaag gtttctatgt attagttaac
    26881 ttcaaatcag cagtagacgt tcctaaagag atagacagaa acttaaagat aaatgaaaac
    26941 gtaataagac acatgatagt tgttgcttaa taactggttt tattataaaa aataggtggt
    27001 gtttttatga atcaagttgt attagtggga aggttgacta gagaccctga attaagatac
    27061 atcccaggta caggaacacc agtggcatcc tttacaatag ccattgatag agactatgta
    27121 aaaaaagatg gatctaaaga aactgatttt atacctgttg aagtaatggg gaaatctgct
    27181 gaattttgtg ctaactacat aactaaaggt agattagtag cacttcaagg atctataaga
    27241 gtagacaatt atcagacaca atcaggtgaa aagagaactt ttacaaaagt aagtactaga
    27301 tcagtacaag ctttggatag taagaataaa tcggaaaatt catatagaga gagtgctcca
    27361 gcttttgagc caagctttga acctcaaggt ttagacccac aaggtttcca agctatagat
    27421 gatgacgata taccatttta aaaaggaggg aaaaaagtca tgatgaataa gaaaagacgt
    27481 aagaaaaaaa gagtttgtca attttgtgct gacaaaaacg ctaaaataga ttacaaaagt
    27541 actcaaagat tacaaaagta tataactgaa agaggaaaga tattaccaag aagaatatct
    27601 ggaacttgtg ctaagcatca aagagaatta acagttgcta taaaaagagc gagaaatata
    27661 gcacttttac catatacatt agactaaaaa aatgagcctt gtgctcattt tttattatat
    27721 gtatttatat atctaaatga ggcgagctat aaagctcgtt tttttgttta tatacttaaa
    27781 tatattatta tttatgatat aatattatat attaaggagg gttgtaaacg tgaaaataga
    27841 taaaggttct gagataacaa gaaacataaa gataatagaa tggatgaaaa cagaaatatt
    27901 aatgagtgta agtgatttgt ttaatttatt gtttaaaggg gtaaaaccat tagatgaagc
    27961 aattcaagat actttagcaa atataataat gataacatat ctcttagcaa agagattagg
    28021 aattagtttt agagatgtgg attataaagt caaggaaaaa ataaaaattg gtatagatga
    28081 ggaccatagc gttgaaagat ggtatggaga tttatctaat ttaaaaaaac atatggataa
    28141 tagggagtga tattaaattg aataataaaa ttagactatc taaggcaatg tctataatag
    28201 ttttagctat aataatcgct ttagtaatag cctatattcc aatgctagga atatttagta
    28261 tgttagcagc tgttccatat gtaattatag gtgctattac tgatagaaag tattctctta
    28321 tatctatttt ggttacattt tgtgtactga ttctatttgc agacatttct tatgcattaa
    28381 atatatgtat aatgtattct ttaccaggta tagtaatagg aaagatgcta aagagaagct
    28441 ttgaacaaga ggacagtaat aaattcgaac cgatatatgg tggaaccata atatttgtac
    28501 tttcaatgct tgtatatttt tttgtattaa agacattttt aaatgtgaat ctattagatg
    28561 aagtttctaa gatgatatca gaaattgtaa atattcaaaa aaatagtttt tctgcaactg
    28621 aacttaaagt gtttgataaa atgaagccag atgagattgt aagttatttt acaaatatgc
    28681 taccaatgat gttattttta caagggttgt tatcagcgtt tgtcacatat tatttgagtg
    28741 tattttttat aaaaaggatt acaaagatga atataagatt tcctaagttt gctgattttt
    28801 atttaccggg aaatgctata ctcacaactt tcttacttta tttattagtc ttatttattc
    28861 aaattattgg ttcaaaatta tatacagaat taataatgac taatttacag ctagttttta
    28921 atttaatgtt tgtaattcaa ggtatagcag tttgcattta tttcttaaag aaatggataa
    28981 gacagggacc aaataaaatt atgttttttt cagggataat tttatgttta tttggattta
    29041 tgggaatatc ttttgttggt atggtagata gtataattga ctttagaaag gtaagaagct
    29101 ataaatccac ttaggaggat agaaatgagt aataaacaaa cctttaaatt aaatatgcca
    29161 gaaataaatt tatatataat tgttattggt atttctagta taattttgct ttattacaac
    29221 ttgtatgtag ggtgtttatt tttctgtatt tttgtatata tggtttttca caattggaga
    29281 actactaata ttagacgtca tgaatggaca gagtatattc aaaatttatc tttagatata
    29341 gatgaaacaa ctaaaaaagc cataataaat cttccaatac cattatgtat tttagaattt
    29401 gatggaaata tatcctggta taatggaaag ttttatgata tgattggtca aaaagattta
    29461 cttgataaaa atatagagga tatagttaaa aatcttaatt taagaaaagt attaaatgaa
    29521 aataaagaga tgtacacaga aataaactat aaagaaaaag aatatacaat aatttataat
    29581 gttataaaaa atgatcaaga aaaaaatcct aaatatttga tgatattata ctggatagac
    29641 aagactgaat atttaaaagt aaaacaaaat tatgatgatg aaaaaaatgc aatgatgcta
    29701 atacaagtag atggatatga tgaagtatta aaaagtgcag cagaagataa gagagcttta
    29761 attaatgttg aagtagagaa aatactttct gctttagaat taaattcaaa tggtgcattg
    29821 agaagaactt caaaagacaa attcttcttg gtaatgcata aaaaagagtt aaaaaaattg
    29881 gaagctgaga agttttctat tttagataca ataagacata ttgattatgg aaataatctt
    29941 cctgttacta taagtatagg aattggtata gatggagata cattaaatga gaacctaaaa
    30001 cttgctacgg gtgctctcga tttagcactt ggtagaggtg gtgaccaggc tgttgtaaaa
    30061 acaaaagata aatttgtgtt ttatggagga aaatctaaag ctgtagaaaa gaaaaccaaa
    30121 gtaaaatcca gattaatagg tcatgcttta agagaggtta tacaacaaag tgaccaagtt
    30181 tatataatgg gacataaata tcctgatatg gatgctatgg gagcagcagt tggtgtttat
    30241 gatatatgta aatcctgtaa caaaactgca aacatagttt tacaatctgt aaatgaatct
    30301 atagaaatat ttataaataa aataaatgaa aataattact ataaaaagtt gtttattgga
    30361 aaagaggaag ctattgacaa ctgcactaaa aatacattag ttgtagtagt tgatactcat
    30421 agaccaaatt atactgaatg tgaagaactg ttaaagctat cagagaaggt agtagttata
    30481 gaccatcata gaagaggtgt agagtttata aatgatgcag tgcttttatt ccatgagata
    30541 tatgtatcct caacgtgtga aatggttaca gagttagttc agtatatgga tgaagatgta
    30601 acaataaata aacttacagc tgaagggctt ttagcaggta taagtctaga tactaaaaac
    30661 tttgcattca aaacaggtgt tagaactttt gaagctgctt cttaccttag aaaagttgga
    30721 gcagatacta tagaggtaaa gaaattcttc aattctgatg taaaagattt cataataaaa
    30781 gctgaaataa ttcaaagtac taaaataatt aataatagaa tatgtttagc atattcaagt
    30841 actgagatag atagtataaa tgttataata gctcaaactg ctgatgagtt attgaatatc
    30901 aaagaagtag aagcttcctt tgtattaggt gaaaaagatg atactatatt tataagtgcg
    30961 aggtctttag gacaaataaa tgtacatgta cttatggaaa aattaggagg cgggggacac
    31021 atagatatag ctggagcaca gttaaaaaat gtttctctaa aagaagctta taagatggta
    31081 aataaaataa tagaggagta tttggaggag gaagaataga tgaaagttat attattaaaa
    31141 gacgtaaaag gaactggtaa aaagggagaa atgaaagaag taagtgatgg atatgcaaga
    31201 aatttcttat ttcctaaaaa gatggctgtg caagcagata gtgtagcaat aaaagaatta
    31261 aatgaaaaga ataaatctaa agaaataaaa gcacaaaaag agtatgaaga agcagtttta
    31321 ttaggtaagc aaatggaaga aattaatata gaaatatatt caaaagcagg agaaggtgga
    31381 agattatttg gttcaataac ttctaaagaa attgctgagc aattaaagaa acaaaaagac
    31441 atagatgtag ataaaagaaa aatattatta gatgaaccga taagatcttt aggttcaact
    31501 ttcgtagaaa taaaaataca tcaaaaagta actactaaaa taagagtgga tgtaaaagaa
    31561 aaacagtaat aactagaggt gattaagatg gaagatatga cgagaattcc tcctcatagt
    31621 gtagaatcag aacaatcaat attgggttct atacttctag ataaagatgc tataataacg
    31681 gttacagaaa ctataaagcc tgatgatttc tataaagagg ctcacaaaat aatatatgaa
    31741 tgtatgataa ctttaagtaa taaaggtgag cctatagact tgataacatt aacagaagaa
    31801 ctaagaaaac aagggcatct taatgatatt ggaggaatca gttatattac aagtctttct
    31861 actatagtac cgacgacttc aaatgtaaaa tactatgctg atatagtaaa agaaaagtct
    31921 gtacttagaa agcttataaa agcttctaat gaaataataa atctaggata tagtggagca
    31981 actaagattg aagatgtttt agaacaagct gaaaagagta tatttgatat atcacaggag
    32041 aaaactagtg atgattttaa atctataaac ttagttttga tggatgccta tgatatgata
    32101 gaaaaattat acactaacaa gagtgatgtc actggtataa ctactggttt taaagattta
    32161 aacaaaaaaa taaatggtct tcaaaggact gatttaatat taattgcagc tagaccagca
    32221 atgggtaaaa ctgccttttc tttaaacttg gttcaaaatg cagccttaaa aggtgatgcc
    32281 tctgtagctg tatttagttt agagatgtct aaggaacaat tagtacaacg tatgttatct
    32341 tcacaatcta gtgtagaatt aaaaaaaata aagactggaa cacttaatga taatgattgg
    32401 cctagaatta tagatgctat ggcagtatta tcagatgcca aaatacacat agatgatact
    32461 cctggtataa aaatatcaga actaaggtca aagtgtagaa agttaaaaat agaaaaagga
    32521 ctagatttag tgcttattga ttatcttcaa cttatggaag gtgaaggtaa taatgaaagc
    32581 agacaacaag agatatctaa gatatcaagg tcactaaaaa tattagcaaa agaattaaac
    32641 tgtcctgtag tagcactatc tcagttatca cgtgcaccag aacaaagagc agaccataga
    32701 cctatgttat ctgatttaag agagtctgga gcaatagaac aggatgcaga tatagttatg
    32761 ttcttataca gggacgaata ttatcatgct gattctgaga gtaaaaatat aggagaagta
    32821 ataatagcaa aaaatagaca cggtgaaact ggttctgtgg aacttgtttg gcttggtgaa
    32881 gttcaaagat ttggggataa gttgagagac ctataatcta acgaatatcc acagaacgtc
    32941 ctttctttct acaggaaaaa tgtggataca tgtcactaaa tatgtccaaa cattgaaatt
    33001 tagctaaaaa actatccaca ctatccacag atggcctgtt gataagtgtg aataagtaga
    33061 taaagcaagc ttttggcttg ctttatctgt gtataaatat taattattag gaggaataat
    33121 atggaaaaaa taagcttaat atatatatat cccaatataa ttaaagtact tgatgaaata
    33181 aacttattta gagtaattga caataattta agagagtcta ttgttgttta tgctaataat
    33241 gtggataatc agtatcatat aaacatgact aatacaaact ttggaaacat aattaacata
    33301 tgtaaattag aaaaactttt agatgtggat aaatttatgg aaaaagttat aaaatatgaa
    33361 aaagaaataa tagagaaaga agagttttca aaaatagaag aatatatgtt aaatattgga
    33421 gaatactaaa aaagttgaaa aaaatacgaa tgtttgatag aataagtaag taaagtgttc
    33481 gagagtatat aaaatataga ggtgaattac atgaaaacag ttgcaattgt tggttctcaa
    33541 tggggagatg aaggtaaagg taaagttata gattatcttg ctactcaagc agatgtagta
    33601 gtaagagggc aaggtggaaa taatgcagga catacattag ttgtagaagg taaaaaatat
    33661 gcattacatc taattccatc tggagtttta aatccaaata cagtgaatat aatcggaaat
    33721 ggaatagtgt ttgaccctaa aggattttta gaagaattgg aaatgtttaa aacggataat
    33781 ataagtacag aaaatataaa aataagtgat agagcacatg tcatattccc atatcataaa
    33841 gaactagatg cattgtcaga agaagccaga ggcgatttaa agataggtac aacaaaaaaa
    33901 ggtattggac cttgttatat ggataaaaca gagagatctg gtattagaat atgtgactta
    33961 atggataaag ataaatttgc tataaaatta aaagctcaaa tagatgctaa aaatgaaata
    34021 gttaaaaata tatatggaaa agaagaatta tttgattttg aaactatata taacgaatat
    34081 ctaggatatg cagaacaaat aagaaaatat gtggcagata cgtctgttat tgtatatgat
    34141 gcagtaagag caggtaaaaa agtattgttt gaaggagcac aagggacttt attagattta
    34201 gatttaggaa cttatccatt tgttacatct tctcatccaa catctggtgg atttgcaatt
    34261 ggtgcaggta taggaccaaa tatgataaaa gacgttgttg gtatagtaaa agcatatact
    34321 acaagagttg gagaaggacc gtttgttaca gagcaaataa atgaaactgg agataagata
    34381 agagaacaag gacatgaatt tggggtaact actggtagac caagaagatg tgggtggttt
    34441 gatgcagtta tagttaagta tgcagctaga gttaatggat tgactagtat ttcatttatg
    34501 ttacttgatg tattaactgg atttgataag ataaaagttt gtacgtctta taaaatgggc
    34561 gataagataa taacggattt cccagcttca ttagatgatt tagcaaaatg tgaacctgta
    34621 tatgaagaat tagatggatg gaatgaagat ataactcaaa tagataactt tgatgacctt
    34681 ccagaaaatg caaagaaata tgtagcaaaa atagaagaac tagttggagt aagtgtagat
    34741 atggtttctg ttggtccaaa tagagctcaa actataataa gaagaaatat atttgcttaa
    34801 tattttatca attaaataat ttaaaatagt tgaagaagag tatctcaaga taatgtttat
    34861 agttattaga gatgctcttt tatatttgac ttacattgat tttttattaa gttaaagcta
    34921 cttatacata ttctagctga aattaaagtt gaatttatgt agatacatat aggtttttta
    34981 aaaagaattt tgttgaaaat aaatggctaa agatgatttt aattatattc taaaaaaagt
    35041 aaaaaaaact attgactaaa aattatatag acgctataat ataacttgtg agtgaaagaa
    35101 acgacgaaaa aagtcgaaaa aatgtggtct attagctcag tcggtagagc acctgacttt
    35161 taatcagggt gtcccgcgtt cgagtcgcgg atagatcacc aaaatatggc tcgttggtca
    35221 agaggttaag acaccgccct ttcacggcgg taacaggggt tcaattcccc tacgagtcac
    35281 cagtatggga ctatagctca gctgggagag cacctgcctt acaagcaggg ggtcacaggt
    35341 tcgagccctg ttagtcccac caaattttga attagagata aatactagat tatatgctgg
    35401 tgtggctcaa cggtagagca gctgacttgt aatcagcagg ttgtaggttc gattcctatc
    35461 accagctcca caaagtacat aaattcaaat taatataatt ttctatgtta caggatactt
    35521 ttaagtatct ttttttaatt tcatttttat tgtattaaaa atgaaattaa acatacaaca
    35581 aaattttgaa ttacttgcaa tgtgatagtt ttaaatataa aatttagaat cattctagca
    35641 tagtattatg taatatagca aatttaattt atagtatcaa taaatataga ctactaagaa
    35701 tgtaaatgat ttgttagatt aagatacatt agatatgtaa atagaaaaat aaaaagtatg
    35761 ttttaattta tgtgatataa gttttaaaca gagaagcaag tttgctctta cctctctatt
    35821 taaaaataaa aaaatgtttt ttaagggcta ttttatttaa atctttccca tctcaaatca
    35881 tctccagtaa attctaaaat cctaaactta tctaatattc tagagagagt tctttgagtg
    35941 taagtatttc ctatttgaga tggtgttaag ttggttgaaa taatgatttt tttaccagca
    36001 acaagtcttg tatttacaat attgaagatt tctccactag taaaagaatt attaagttca
    36061 gttccaaggt catctattat taataaatca caatcaaaca agtttttata attatcttca
    36121 cttatttgat tatttgtgtc tcttctaaat ttataatctt caagaatatc taaaattcta
    36181 aaagaagttt gatagattac aacattgcct ttatctaaca attcctttgc aatacaattg
    36241 cacatatagg tctttcctag tccagtagaa ccataaaaca gtagattttc actattatcc
    36301 ttcttaaaat catgaacaaa attttcgcag atacttaaat tatttagcat attttctcta
    36361 ggagatattt caccatcaga gcctttctta ggagaaaata tattcaagtt aaaattcgaa
    36421 aaattttcct gacttaaaat cctatctaaa ttagacattt tataagcttc atttacaatt
    36481 tcttgtttga ggcaagaaca tttttctcca ttaggtaaaa atcctttatc tttacaagaa
    36541 atacattgaa actttatttc caagtaatca agaggtatgt tactttcagc taaaagtctt
    36601 tctttcttta cttttaaaga ctctatattc tctttagtct tctttacaat ttcatcttta
    36661 gacttaggat ttaaaagtac tatcttagct aaactgagac ctattttaga aatttcatca
    36721 tctatagatt ttatctcagg gattctatta tatacctcat tttttctatg ttctaataag
    36781 agttcattat catctcttct cttagcatat ttagcaagta tttttcttat tttatcctca
    36841 ttcatttaat cacctactta aacttttctt tttgactttt tttaataatc tcatcgagct
    36901 catcagaggt atactgagtg aatgtttcgt tgaaattatg aaacttagtt tttttgtaag
    36961 tattgttgtt ttgagtagta ttaatctgct tcttattaat attctcctta actatacgtt
    37021 cttcctcttt ttgctttaaa tcatttaaat tttttatatt tttttcattc caatttttaa
    37081 ttatgccatt tatataagat atacttgggt ttgaaatatt cttagactta gaacatgcat
    37141 ttattatcaa atctatatcc atattaaatt tatcaaacca ggtgtccata agttcttttt
    37201 ctgattttga tggttgtctt gaaaatccca attcattgaa aatcgtttta tataaaatat
    37261 atcgttcact tcttaccaaa aagctttctt caacatcttt tggcgtatat aaatttgaat
    37321 cataccaatt tctaataatg ccttcaatgt atttaactgg ctttgatgta ccagttttat
    37381 ctttgacgta ttcatatgcg caaagtatca tatcggggct catattgtat ttattcatta
    37441 tatccataat actcatcttt tcacttgggt ctagatatcg cccaactatt ttatttatag
    37501 aattaaacat ttttctaata cttggatttt cagaagtaga tacaacctta tctgtattag
    37561 attttataga tgaattattg cttaatatat tctcaatata gaaatttttt aaatctaaaa
    37621 attctattga ataattaaaa ttatcatatt ctccattgtc atgtattttt ataatcttct
    37681 tttcttccca gaatttccaa gcagataaca catcagacaa tggtatattt aggtttttgg
    37741 ctattgaatt attgtcgaac ttaggattag aagtaatatc acatgcttgt ctatatccta
    37801 aaagataaac ttttacgtat aacccgtccg ccattggcat aaatatatct ataaagatat
    37861 tgggaatagt gatttcacct aaatctattt cattgctttc tttaaaaaac attttatcac
    37921 ctcagattaa attatatcat tttttatatt atatttgtct gtaaacaaat aaaaggtcac
    37981 aagattagca tgtaaatatt ttctaaaagt attcattttg aaaaggagga gatattttgg
    38041 ttataaaatt caaccaaaaa gtaagaagaa cattatcagt agcgattcta tttatggtat
    38101 taataatagg ttgctttata gaaaaggatg acagtttaga aacatacaaa gaaaaaacta
    38161 attcaaaaat aaatcagtat aatatggatg ttatatttga tgatgagact aagaggttaa
    38221 tgtgcaatca gaatgttgac tacataaata atacaaaatc aaacatagat aaaatatatt
    38281 tccatatata tccgaatgct ttttccaaga aagattttgc tccttttgaa aaaagtgaaa
    38341 tgacaagggc ttatcctaat ggatttaacg aaggatatat agatataaag aatatattaa
    38401 ataataatag taaaatggag tataaaatta aaggagataa aaatgacata ttagaaatag
    38461 aattagggaa agagttaaaa ccaaatgaaa gaatgtcatt agatataaaa tataacgtaa
    38521 aaataccaaa ttcaattgga agatttggat atggagaaaa tactataaat gttactaatt
    38581 ggtttcctat agcttgtgta aatgatgaaa ggggatggaa tttaaagagt tatgaaacta
    38641 ttggcgaccc attttatagt gagactagcg attttcatgt gaaactattg attccaaata
    38701 aatataaaat tgctcataca ggaaaactta ttgatgataa acatgataat aagaaaatgc
    38761 tatatgaaat agaagctgaa aacgttagag attttgcatt tatactaagt agcaaatttg
    38821 atgtaaacaa agtagattca aagggagtag ctatcaatac atataattta aataaaaagc
    38881 tttctaaaaa agcaactgaa gtggcaaaag attcaataaa tatatttagt gaattatttg
    38941 gaaagtatcc ttacaaagaa ttttctgttg tagcaagtga cttttttata ggggggatgg
    39001 aataccctat gcttgttatg atagaccaaa gtttatataa tgaaaaaaat gaatttttac
    39061 tagaatatgt tattgcccat gagacagcac atcaatggtg gtattctgct gttggaaatg
    39121 atgaaataag tgaaccctgg ttagatgaag cacttactga atattctaca atagtttatt
    39181 ttgaacaaaa gtatggtaaa gatatggcaa acaagcttat aaaaactatg gagatacaga
    39241 caaaaagtta tttgagcgaa aatatattta agccagcaaa tgagtataaa aattctactg
    39301 aatacagctt gaatgtttat acaaaaggcg caatagcatt taatgaaata agaaaagaag
    39361 ttggagataa agtattcttt gagactttaa atgagtacta taataagtat aagcataaaa
    39421 atgctaatgg aagagctttt gtggaactat ggaatagtaa aggtgtagat ataaataaga
    39481 ttataagtga atgtaagtaa atagtgaatg taagtaaatt ttgtgcagag tattaaattt
    39541 tatttaatac tctgtttttt tggtataata taatttataa ggcagaaaaa gaggtgaagg
    39601 aatgctaaag tattgttcag tagggagtgg tagtagtggt aattgccact atatagggta
    39661 taaaaatact aatatactag tagatgcagg attaagtggc aagagaataa ctacaggtct
    39721 taaagacatt ggtgtagatg cagataaatt aaaaggaata tttataacac atgagcatgt
    39781 tgaccatata aaaggagcag gtatattatc aagaaagttt gatataccag tatttgctaa
    39841 tataaaaaca tggtgttcta tgaaggacaa attaggtgac atcaaagata aaaatatgaa
    39901 agtatttgaa aatgataaaa cctactcatt aggtgatatc atagtaagac ctttttcaat
    39961 agaacatgat gcgtctgacc cagttggata taatttttat acagagagtg atgaaaaaat
    40021 gtctatagct actgatatag gatgtataac tcaaaatata aaaaaacatc tatataaatc
    40081 taaattagta gtattggaat caaattatga ccctaatatg cttatgatgg gttcatatac
    40141 atatgcttta aagaaaagag taatgtcaag tactggtcat ttatccaatg aagatgcagc
    40201 taatttctgc gttgaactta ttaatgaagg tacagaatct atattattag cacatttaag
    40261 taaagaaaat aattttcctg agttagcgta tgagacttca aaaggagtat tagcatcaaa
    40321 tgatatagta gttggacaag atgtaaaact agatgtacta tcacgaaatg atgtttctaa
    40381 tgtttatgag atgaagtaga ggtgaataac tttgctaaag agaaattttg aaaatgttga
    40441 ggataataaa attttatact ctataaagca gggcatgatt ttagcgatac ctgctattat
    40501 gactggttca acggctcttg taattttgaa tcttccaata aaggcttatc aagaatattt
    40561 atcaggcttg tttaatggag aggttacaaa tattcttaac tttataaatg attctacttt
    40621 aggaattatt tcattaataa tattattaac aataagctat agttatggaa aaatatatgg
    40681 gagcaagtat acagtacttg ttcctatagt tgcaatgtgc tcttttttag tattttcgca
    40741 tggtaatgag cttaattctt atatagaaat atttaagaca aagtggttat ttacatctat
    40801 aattgtttct atgacatctt ctgtattgtt tgtaaaactt acagaatctt ttgttacaag
    40861 tgtaaaattt catacagaag gggctgatgc agactttaat atggtagttt cggctatagt
    40921 tcctttcata atagtagtat ttttgttttc tatttttaga gtgataatga taagtctaat
    40981 tggcagttca aactttcaag atatatttta taatttattt tcaaatgttt ttaataaaat
    41041 gggaacaaat cttatgagtg ctctgttgtt tattttttta atgcacttta tgtggttttt
    41101 tgggattcat ggtagtaatg tattagatac cgtcgcaaaa aatttatttg aaaatagtat
    41161 ggcaattaac ataaatttag ttaataataa tcaattacca acagaaattt ttactaagac
    41221 cttttttgat acaatggttt tattgggagg atgtggctct ttactatgtt tagtaattgc
    41281 aatttttctt agtgaaaaac gtataaatgt aagaaagtta gctaaaattg cttcaatacc
    41341 agctcttttt aatatcaatg agatgctagt tttcgggata ccaattgttt ttaactatat
    41401 tatgtttgta ccttttgtaa ttactcctat aatcttaacc atcacaagtt atgtggctat
    41461 gtctacaggt attgtaccat gtacagtttc agctgtagaa tggacctcac ctatattttt
    41521 aagtggatat atgtctacag gttcaataag aggtagtttg ttgcaagtat ttaatttatg
    41581 tgttggtgtt atgatttata ttccgtttat aaaaatgtcg caaaatagat atacatatat
    41641 gtttaaaaat aatatagaaa atttaacaaa cttattaaaa aggtatgaat taacaggtga
    41701 acagcctaat cttctaaacc ataatggtaa aataggttca atttcaaaaa tgttggcatc
    41761 agacttgaag tttgctatga aaagaggaga aatagagctt ttttatcaac cacaagtcaa
    41821 ttataatgga aatgttgtgg gagcagaggg attacttaga tggaaacatt caataggagg
    41881 gttcatttat ccaccactag ttataatttt ggctaaagaa gaagggttct tagatgagct
    41941 tggagagtat attattaata aagcatgtat tgatttaaag aagagtgaaa agctattgag
    42001 aaatcctgtt aagttctctg taaatatatc tccagaccaa cttgatgacc ctaagttacc
    42061 agagcaaata aaaaatatca ttagtagtaa tgatataaat cctaatatgt taggtataga
    42121 aataacagag caaattgcat tatcaggttc acaaataatt attgaacgta tcaatgcgat
    42181 acataacttg ggaataaagt taattatgga tgattttggg atggggcata gctctcttat
    42241 atatcttcaa aataataact ttgatatagt taaattggat ggttcattag ttaaagagat
    42301 acttacaaat aaaagaagta gtgaaattat aatgactatt gtaaatcttt caaaaaattt
    42361 agattttgat atagttgttg agtatgttga aaatatagac caaagggata agttatatgg
    42421 tttaggatgt gaaatatatc aaggatatta ttatagcaaa gcaatacctt ttgaagagtt
    42481 tgtagaatat gcaaatcaag aaagagagat ataattttat aagagcttgt aaattctagt
    42541 aatgcataga tttgtaataa aattaagttt aggagaaata tatgaatata agtatagtag
    42601 tagtaggtaa aattaaagaa aaatatttaa aattaggtat tgatgagttt aagaaaaggc
    42661 tttctaagta ttgtaagtta gaaattatag agttggatga tgaaaaagct ccagagaatt
    42721 tgagtgttaa ggaaatggaa attataaaag acaaagaagg aaagaaaatt ttagggaaga
    42781 taaagcataa tagttatgtt atagccttgg ctattgatgg gaagggttta tcctctgaag
    42841 aacttgctaa gactatgagt gatttagcag ttagaggtaa tagtagtctc tgttttataa
    42901 taggaggttc tctagggctt tctgatgagg ttttaggaag ggctgattat aggttatctt
    42961 tttctaggat gacttttcct catcagatga tgagattgat attgttagaa cagatttata
    43021 gggcttatag gataaataat ggagaaccgt accacaagta acggagcgca gttttaatct
    43081 ttttacaatt aaataataaa tctttgtaaa aagatatatt attggatata attgttatta
    43141 agtacaaagt aaaggggtta ataacaatgg cagataattg tatagtttgt ggtaaatcac
    43201 ttagtatctc acaatatagt ggagatggaa agtataaatc atgtccaagc tgttctcaaa
    43261 acaatggaaa agaacatgtt tactatgaat atccagaaca ttttggaaca acgcaaaaaa
    43321 gggcatcagc aaaaaggcca gaagggcctc aaagtcactg tgaaagttgt aggtttgaca
    43381 ggggaacata tccaaaagag acattgtgta gagaaataaa taaatagaga cgtatataaa
    43441 tttacttaaa aagaggtaat gctatttaaa taggattacc tcttttttat ttaaaggtag
    43501 taattagtta actctattgt attaagaaag taaatactat ataatgaaat gatgtagtaa
    43561 caaagtgtag taacaaaaca tagtgacaat aacaaaataa catagattga aaatagaata
    43621 taaaaggggt ataaaatgac taattttata gaggataata aagatgagtg tattagattt
    43681 agagtaagta aaaaacaaaa agaattaata aaatcaatgg ctaaagatag taatttaagt
    43741 atgacaaggt tcttattaga gttacttgag ttagcaagaa cagataaaaa tatattagaa
    43801 aaactaggag gaaataaagt tgagtagaaa aaaaaatagc cttgtagctc ctgtgcttaa
    43861 gtgggttgga ggaaagagac aactaattcc agaaatagaa aaatattttc cagacaaata
    43921 ttcaacttat tacgagccat ttattggtgg tggagcagta ttgtttaatt ttcaacctaa
    43981 aaaggcagta gttaatgaca taaatgaaga actaataaat ctatataaag tagtgagaga
    44041 tgatgttgaa tctctaataa aagatttaaa gaagcataga aatgaatcgg aatatttcta
    44101 tgaaattaga agtttagata gaaatagaga aaagtatgaa caattgacag atattgaaag
    44161 agcatccaga atacatttct tgaataaaac atgttataat ggattattta gagtaaataa
    44221 ttcaggagaa tttaattctc catttggaaa atacaaaaat cctgatatag tgaatgaaat
    44281 tacattaaga gcagtaagta aatattttaa taataatgat attagtttta aatgtggaga
    44341 ttttgaagat tcactaaagg gaattagaaa agggtctttt gtttacttag atccaccata
    44401 cgatcctgta tctgatagct ctaattttac aggatatgca aaaggtggat tcaatagaaa
    44461 agaacaagaa cgattaaagg agctatgtga caaattagat tcaaaaggag ttaagttttt
    44521 attatcaaat tcatcaactc catttataat ggatttatat agtgattaca aaatagaaat
    44581 aataaaagca aaaagatcta taaactcaaa gggtgacaag aggggagacg tagatgaagt
    44641 gctagtgaga aactattagt aaaagtaaaa atgatatagc atgggagcaa atatttaaaa
    44701 agtataatgt attagaagaa ataaataata ctggatattt tagagtaact gcatctcaga
    44761 ttggtgagtt tagggaggct agattaatgg ctaaattcga tcacaagagt cagttgcctg
    44821 atatatttaa aaagcatagt ctttctatat taccaatagc aagagggagt tatataattt
    44881 ctcaatttga agcatataaa tcttttgaag atataaacac tgaaattact aaggtgaaat
    44941 ttccagagta tatagaaagt atagattatg aatgtattac tagtgaagct atggctataa
    45001 attgtgcata tgtatcaggc ataatagctg attttatgga agatgaaaga atacttcctg
    45061 tcgtaagtgg aagaatgagt tctttagaat ttgaatttat tataaacaat acaaagcaaa
    45121 aggataaact tccagtatat gtaagtaatt cgcaaattga gatagatggt ggatatgaag
    45181 ggattgaaaa tttagcttta atagaagcta aaaactctat ttctgatgac tttttgataa
    45241 gacaattata ttatccatat cgactatgga gtaaaaaagt gtctaaaaaa gtgaagtcta
    45301 tttttatgac atattcaaat gatatatttt cattttatga atatagtttc ttagatccta
    45361 aaaactacaa ttcactagtt ttagtaaagc agaagaatta tataattgat caagaagata
    45421 tttcattagg tgatatttta tcaatcctac atgatgtaaa attgaaaaaa gaaccagaga
    45481 taccatttcc acaagctgac aattttaagc gaataataaa tttatgtgag ctactattaa
    45541 atgatgatat gaataaggaa gatatagtat caaagtatga ttttgatcct aggcaagcag
    45601 attactatac aaatgcaggg atgtatttag ggctaataaa gaaaaaagat actaatccta
    45661 taatatattc tttatcaaac ataggaaaaa aaattataag gcaaaaacat agagcgagac
    45721 agttaagttt agtaaaatta atattagagc atgaggtttt taataaatca attaaattat
    45781 atataaaaaa gggagaaagt cctactaaaa atgaaataac aaatttgatg aaagagtcat
    45841 atatacataa tgtaaagtca gaggtaacaa tgatgagaag atcatcaact gtaataagtt
    45901 ggactaactg gattctttct ttagtaaata ttgattaaaa taacagagtc acccttggta
    45961 aatagatata ttttgagata ctgcatattt gtgtagtatc tttttaaaat ttaaaataaa
    46021 tatttgtatt aaaatttagt tttgaatata tattataatt ataataaagc taaatgaggt
    46081 taaaaaactt catctagctt attttgtttt caaaataagg aggaagatac aatgataata
    46141 aacatttgga aaaaacaaga cttagactta gtaaaggaaa tacccaaaga agtactgtct
    46201 acaatagaag atacaataga aataatagat gaaaactatg gtacaaaaag aacggcaaaa
    46261 gacttaggtg gatacgtagc tgtagtagat aaagctggaa taaaagagct aaaacaacac
    46321 caactaaaag gaataatacc tgaatacata gacgaaatag aaggagctga atatatttca
    46381 gctctatttt tgtgttcaaa tgacttctca atagtagttg tttgcaagaa agaattaaag
    46441 aatctaatag aaatagataa ggaacaatag gtggaacttt tcaagggata attacagaag
    46501 aaactttccg tagaagtcgt tattattaat aagtaccgac agaggaggtg gagcatgaaa
    46561 aaggataaga gtgactatag aggaatctat gcagaaatgg tagagatttt aggagaagaa
    46621 atagtaaaga tgatacataa gcactataaa ggtcagcaga taaatctacc tatgaagctt
    46681 cattcaaatg aatacgtaga aaaatacatc attgaaaata aagataagaa gagcctaaga
    46741 gaaatgtcta gagaactagg ttactctgat agatgggtaa agagactaat aaataaactt
    46801 aataaagaat agcacaattt ggaggagaat aataaaatga tactgggagt aatagcaata
    46861 attttagcaa cagttatatt ttttctagta aattcaatgc tagacataac atattttgga
    46921 tgtggagcaa taggaactct ttggtttgga tgttttgtca tagcttacat aatattaact
    46981 tcgctaggag gaattttcat agggttatta aagtggatag taataggagc agtaatatta
    47041 gggataatag gattaattgc agggtcaaca aataaagcag aataaatatt aactaaagag
    47101 atagtcgata aaaagactat ctctttttct atgtctaaaa gaaaggatga agataaatgt
    47161 ttgataaaga tagatactta actagaggtg tttcagagga aataccatta gaaatacaga
    47221 tactactgtg gtcaatgata gtaggaataa aaataaaaaa agactattta caggtgtttg
    47281 aaatagagcc tataaaaaat aggttactta agatagagca taggcaggaa atacctaagt
    47341 ataaaaaagg gcatgtagta gtaaatacag gaataaattc taaagtaaag atatttgtaa
    47401 tagacgatgg ggagtattca acaatgatgt tgagtagtga gtactaataa aaaggagaaa
    47461 tgaaatgagt aaaataataa aagaaactaa atactgtaag gtacttagac aagctaaaat
    47521 tagagaagat aacatagctt acggaataga aaaaatattt gtaaaagaac taaatcaaga
    47581 agaaataaga tttgtttact ttaaagatac atacagacaa gaggaacaat tagtatcaag
    47641 accattggat ttaccagaag aagatttact aaaattaatt gaagttgcaa taaaacaaaa
    47701 tgtgttttca aaagagtttt taaataattt aaaagaaata gtaactaagt agattgatac
    47761 taggaggtta aagatgactg tagaactatt tgtagcagga gtaacatttg gaataacaac
    47821 atttaaaact ataataaatc aaaggaaaga atatttaaaa aaataaagga gcaattaaaa
    47881 tgtggggatt tgtaatagga gcagtaatag gtttaggagt ttgtatagta gttgaaataa
    47941 tggtttctaa caaagctata ttggtataaa atagtaataa ggttgacata gttagcctta
    48001 tttttttgac aacaagtaaa aattgaaagg aaattagacg tatgaaatac tatgatttaa
    48061 aagaattagt accagaaata acaggagtag atgaagaaga ttatattcta tggcagtcaa
    48121 cgcttaaaga tatacagagg attgataaat tagtaagagg gatttcatca tatagtgata
    48181 caaataaaat atctgaaagt caaaaagatg atatagtagt cctatatcga acattaaaca
    48241 aagatcgtga aaaacttgat attctaaaaa aattcgccag aaaaaaacat ctaacagaaa
    48301 aagaaagtga aacattattt gatttgtttg taaatagcat gaattctaaa gaagaaagag
    48361 aagaatattc taagcataaa gaggaagtca aatcagaaga attaaaagca ggagttgata
    48421 aaataatatc atcaataata gagacagtaa aagaaacaga agagtttaca tacggagcta
    48481 gattaaagct attagatagt ctaagtaaac atgtagaaat agtaatagag ttccataaaa
    48541 aagaaataca agttgcaaaa gaattaggag gtaaagaaat aaacatactt gaagaagagg
    48601 ctagattgga taaaatatca aaaaaagata aaatacgtaa taattatcct gaatctaaga
    48661 aaaattaaat attataacac taaaacacca aaatgtcaaa gacaaatttg gtgttttttc
    48721 atgtccatga ccaataatta aaaatatagt aagatatacc cataccaaag caaaaagact
    48781 taaatttcaa catatagaca ataaggagga tcttagtatg acgcttaaaa gattaaatcc
    48841 agtagtatta aagaaaaatg gaaagttgat aacttctgaa gaagataaaa gagaagaaag
    48901 gtacatttct agagaactaa agctacctac tgaaatagta gaaacagaga aatcaaatac
    48961 tattcaaggt gtaagtaaaa ttgaagaaaa ataggaggat tctattagag atctagaaga
    49021 aagtaatcaa gagcgaaata ataacatgat tgaaattgat cgtgaactaa atgaacatga
    49081 ggaaaaacta aacgaaatag agaaaataga tgacgactta tcaatctgct acaaaacaaa
    49141 gcaaattgta tacgatggag gaaaaactgc taatttacta gagataagga cacctgaaaa
    49201 aaatattgat acaaataatg taatactacc tataacaaca aaatacttag acagatatgt
    49261 agaaatgcgt gttccaagag ataaagctat gtcaaagagg gagatactta agctaagttt
    49321 acatggagct aatgtcaccg aagaaaatgc aaagtaccac ataaggtcga tagactatca
    49381 agaatgtaaa attggaaaat ctaacaatac tcatagcgaa ttaggttttg ctatgcatga
    49441 tgacaaagaa atctttaaac tagatagggc aataaatgaa gatagcaaat acgttggggt
    49501 attagactta aagcctaaag gtaatttaga agactactta aaagatataa gagaacatgt
    49561 agcaccatat acaaatattt cattagcatt tgcactaggg gtaagttcag cagtagttgc
    49621 taagttgaat cagtattgtg aggatgtaaa tacagtacta tcacattttg taactgaatc
    49681 aagtaaggga aaaagtacag caacaatgtt ggcaatatct gtttggggaa atccaaaatt
    49741 aggggcagga ggattgtata atacttggaa ttctacagaa aatgcactag caacatcact
    49801 agctggaaac tatggagtag catatgcact agatgaactt tcaatgtcta aaatagaaga
    49861 tacgacaagc ttaatttaca atcttgttgg aggaaaagat aaagcgaggc ttacaaaaga
    49921 gatagaactt agaaaattag gaacttgggt aaccacaata atctctaatg gagaagcatc
    49981 acttctaagc agagctaaaa ataatactgg attagaagtg agagtattag agctagaagg
    50041 tatagtttgg acagaagatg caagacattc agacaatgta aaagcattgg caaataaaaa
    50101 ctatggtgtt tttggatata gttttacaga aaaactaatc aaatatccaa tagataagct
    50161 aaaactacta tttgaagagg aaaagaatat tttcaaagct aaggtaaagg aaagaggaat
    50221 agtagataac atgattgaaa gaacggcaac aaaatacgct attgtaacct taactacaag
    50281 actaataaat tcagggtata aggcgtatga cataaactta gacatagaaa gtattagagc
    50341 agtattagtt gaaacagaaa tcagtagcat aaatagaaga ggaatacaaa agagagcatc
    50401 agaatggcta ctagaatatg tagaagctaa tgcatctaag tttaaatgtg ggaaggatag
    50461 taatcaaaat acagactatt ggggaagtag aagagaacta ccaaatggag atttagaaat
    50521 agcagtccta aataataaat tcaaagagat aatgaagcaa ggagggtttg aagatacagg
    50581 ggttgtactt gatcaactaa aaaaagacgg aatgctagac tatgaagaag gcagactaac
    50641 aagaaaaaga aagataaatg caatatctac accagtgtat gtagtaatag ttaaaccata
    50701 gataaaattt aataaataat gaaactataa tcaataatta aaaaattcat agtagaaaat
    50761 aaagtgaaat agtgaaaatt gacttaagac taagtaaatg taatcaagta gacggttaaa
    50821 acgaggtgta aaaatggaca acatagggaa attgacagaa gcagaagtga aaggtagtac
    50881 agcaatagag ataattggtg aaatacttca atcatatctt ttgaaggaag gtaacaagga
    50941 aagtacatca gtagagtaat aaataaggga tagagtacgt gaaaattcac atcctatgcc
    51001 tatagaatac cacgtcagaa gttgagtatt tacaatatat atagataaaa aatcacgttt
    51061 ccacgttgaa attaaaatag atgataaaaa ataaataaac aggagagaaa tgacatggag
    51121 agatacaaac aatataaata cgaagatgta ggagtataca taaaaccaga aatagatgat
    51181 agtgaattac acattcaaac taagttaaat atccttacag aagagctata cgattacggt
    51241 tgtgagccaa ttacaatgtt agaaagcaat gtaaaaggag actataccaa attagaagaa
    51301 ctaatagaaa aaattgagtg gtttagagtt agtgcagtaa taatttggtc atattcagaa
    51361 attgaagaag agttacgaga taagttaagg gaaacttgct ataaaaatgg catagagata
    51421 aatgcatata aagaagatat tcaatcattg ttatttgatt aagaagtaag taggacgtga
    51481 aaattaaaat agataacaaa aaactaaact aggagacaaa caatgaatac atgcagaatg
    51541 aacatataca gtaactataa aaatgaaaac gtagcaattt acgctaagaa aagttcagaa
    51601 aaagaaaatg taaatgagca tataatgggg aaagtaacat ggatgaaaat ggagatagag
    51661 gagtttggtg taaacatact agaatttgta gatagtcata caaaaggaga gtataaagag
    51721 ataaataaac taatagagtt agtaaagaaa agtgaaataa aagcaatctt aatttgggat
    51781 tttgctgata taccaacaga aatagtggaa atattagtag acgaatgtag taaaagagat
    51841 gtgtacttaa atggatttct aacaactata aatacaaaag agataatcta atttaataaa
    51901 taaaaataaa ttacacctaa aaaatagcgt gaaaacgtgg aaataacatt taaacccttg
    51961 gaacaacaca atgtttaacg tgaatctaaa cgtggtttca agggtaatta gtgacaaaaa
    52021 aacgagaaaa tagtatttgg aggacataaa gatgactaaa aaggtagcaa tatattgtag
    52081 agtttcaaca gtagaacaag cagaagaagg atatagtata gatgaacaaa gaagaaggaa
    52141 catagaatat tgtgaaaaag aaggacatga agtttttaaa gtgtatgagg atagagggat
    52201 aagtggtaag aatatttcag gtagaccagg attaaaagag cttttacaag atgctaattc
    52261 tggcaagttt gatttagtaa tagtttggaa actaaataga ataagtagaa agctaataga
    52321 catacttaac atagtagata cactagataa aaataagata gcatttcgtt ctctaacaga
    52381 aagttttgaa acagaaactc cagcaggaaa gctacaactt aatatcatgg gagcaatagg
    52441 agaatttgaa agaggtacta tagcagagaa tgtgaaaatg ggaatgatgg aaagggctag
    52501 agaaggaaag tggaatggtg gaaaagtact tggatacgac atagtagaaa taccaagtga
    52561 aggaaagaag agaaaagata ctaaactagt aataaatgaa aaagaagcaa tgacagtaag
    52621 aagaatattt gagttgtata gtgaaggaca tggatacaaa gctactgtaa atagagtaaa
    52681 caaagaaggt catagaagta agaaaggtaa tgcatttgcg acagctacaa taaaagagat
    52741 actaaaaaat caagtctaca ttggaaagat aagatacaat ttaagacaag attggaatga
    52801 aaaaagaaga aaaaatatca atcctgatcc aatacttgta gatggagaac atgatgcaat
    52861 aatagatact gaaacatggg aaagagtaca gataatacta aaagacagaa gtaagactca
    52921 caatagagtc tatgatagtg aactaattct aagtggacta ttgaagtgtc ctgtttgtgg
    52981 agcatcaatg acagtaagta ggtcaactag aaaaagaaaa gatggaacta aagcagtaaa
    53041 tgagtactat tcatgtggta attggaagaa caaaggaaca gcagtgtgta attcaaactc
    53101 tgtaaaggca gaggttgcag atgaagttgt aataaataaa ctaatagaaa cagtaaacaa
    53161 cgagctatta ctaaagaagg taataaacaa cataaataag aataaatcta gtaagctaaa
    53221 gcctaaacta gatgaaatga acttagtaaa taaggaaatt gataagctaa atggtaagaa
    53281 gaactctagc atagagctat ttgaagatgg aatattagct aagagtgagt tggcagagag
    53341 agtaaagaaa ctaaatgaag agatagatac attgaagttt aggctagatg aaataaagca
    53401 agaggtaatg ttagcagaag gagaaccaat accttttgag ttagtaagtc aagtaatgaa
    53461 gaagtttgga gaagtattta aggagagtag tacaagacaa caaagaaagc agttgttgaa
    53521 tttacttgta tcaaaggtaa caatagataa gtcaagaaaa atagatacta tagagctaca
    53581 gataaatgaa gatgtaataa gatacttagt gaaggaaggg tcgtctgaag aagacgaaga
    53641 cccttccttt tttcatgttt ctatgtttaa ttgtactact ttaaaatttg taatataata
    53701 agaaggaata aaaactaggg ggagagcttg tgaataacac atctaaaaaa ataataatac
    53761 gtacattttg gatatcagta ctatcaatag taataataaa tggaataaac tatatcagta
    53821 taaagtcact tcctatagca cataatagtg attggattcc attctatggt agttttatag
    53881 gtgctatatt aagtggaatt gtagggggat taataacatt agaaggggta aaagaaacta
    53941 ttgatgattc aaaagaagca agaaaaatag atgaaagaca aagaattaga ccatatttac
    54001 atatggaatt agaatcatta gatgggtctt ctaaggatat aaagatagat ataaaaaata
    54061 caggagaaaa tagagggaat agtaaatacc gtatattttc aataagatta aagaatatag
    54121 gattagaatc gtgtgtaaat ataagaatga atgacaagat aatagaaaat agtttgcaaa
    54181 aaggtttctt aactagagaa tttacaataa actcagaatt ctatgatggg gaagaatcaa
    54241 taaataacat acctgtagag attacatttg aagatttaat gggtaattta tataagcaag
    54301 aatattgtat aaatttcttg ggaaatgttg aatacaataa attgagaagg atacaaaata
    54361 atacttctcc tatatatatt gaaacaagaa agtaaaaaca cgctccgttg gaggtgtaac
    54421 ggagaaccgt atcataaata aatgatacgg tttttgttaa tttgacactt aataatatta
    54481 aaataacaaa aaagtattga aagtatattg catttaaggt agaattaaat aaaatattat
    54541 aacattataa tgtttatata gttgttaata aaaatttgga ggaaaatata tgataaaaat
    54601 aatgttggcc tgttcagcag gaatgtctac aagtttatta gttactaaaa tggaaagtgc
    54661 agctaaagaa aatggtatag agtcgcaaat ttgggcaata ccagaatcaa ctatacaaaa
    54721 tgaaatagaa aaatgtgatg tattattact aggaccacaa gttagatatg tattacctaa
    54781 ggctcaagaa attgctaagc catataatat accagtagaa gttataaata tgatgcacta
    54841 tggaacagtt aatggagaag ctgttttaaa tagagcgata gaacttaaca acactaagta
    54901 atataaatta taatgtattt ttaatatata aattgggaga atcaaaggat ggatgaaaag
    54961 attatagaaa tatcttttaa tataataggt tatgcaggtg aaggtaaagg gttagctttt
    55021 gaagcaataa aagaagctaa gaatggaaat atagaaaaag caaaagaatt attaaaagag
    55081 tctagggaag ttataaataa agcacataga tatcaaacag aattaataca aaacgaagct
    55141 agtggaaaca ggactgaaat aagtgtcata cttatacatg cacaggacca cctaatgaat
    55201 ggcatgaatt ttcaacagtt agctgaggaa atcgttgatt tacatttgaa attacaagat
    55261 aaataaaaat taaagagaat aaattaagag agttcttaaa agatacatta tgtgtagcac
    55321 actaattgtt agattattga ttcaatattt agtgagtaat acattaggat tattttgagg
    55381 actcttttta tatttagttt aaagttaata aatatttatt attaataata taagattata
    55441 tgttataata ttataacata taatttaaga ggtgaattat gttaagaaat caaccattat
    55501 atatacaagt tgtagatata ttaaagcaaa aaatattaaa taacgaatat aaaattgatg
    55561 aaaatattcc aacagaaagg gagttagagc aagagtttgg agtcagtaaa attactatta
    55621 gaaaagctat tgagatatta gaatcagaag gatatgtaga gaaaaaaagt ggaaaaggga
    55681 caaaagtaat aagtaatagc ctttttaata agctatcaaa agcagagtct ttttcaagta
    55741 tacttttatc taaaggtcat aagttatcta aagagactat ttcaattgaa aaaataataa
    55801 atgatacaaa ttcacaagta tttagtatat ttggagaaaa atgtagcaag attactagaa
    55861 tgtattattt agatagtaag ccatatatat tttttactca ttatattcct tttgatgaaa
    55921 atctaactgt tgaaagtttt aataatgaaa gttctttata tatgtactta tataggagaa
    55981 atataaatat aactagattt gaagatgaat tttttataga agaatcagaa ctagaggtat
    56041 caaaggcttt aaatctagct aaagacatat tattaggaag aaaaagaaag acctatgatg
    56101 agaatgataa tatagttgag ctatcatttg caagatataa tacagaagta caaaactatg
    56161 taattaaata cgaaatataa taagaatcct gagtttattg aaatgataat atgctcagga
    56221 tttttgttta gttgtaaaaa taaaaaatat tataacatta taatgtttac aaccaaacat
    56281 tataatgtta taatattttt aataaacaag tgatattatc aattacataa aaattagttt
    56341 atgttatgaa atcgttattg cattataaat aaaggataat atcaataata cagggggata
    56401 actatggaaa aattcgcaag ttttttagag cgcaagatta tgcctgtagc agcgaagata
    56461 agtaatcaga gacatatgag agctgtaaga gcaggtataa tagcaacatt accactaaca
    56521 atagtggggt catttttcac aatattatta aacataccta ttgatgctta tatggatttt
    56581 atagctccat ttaaagcaat attagatata ccatttagat atactgtagg atttttatct
    56641 ctatatgcta cttttgggat agcatcatca cttgctaaaa gctacgattt agatacaaca
    56701 ggtgttggta tgcttgcagt tatggcattt ttagtttcta caatagttcc aactcaagta
    56761 gttgaaccag taggtggagt tatagaagct ggtagatgga tggatatggc aaaacttaat
    56821 tcgccatcat tatttggagc tatcgtaaca tcattaatta cagttgaaat atatcgtttt
    56881 atgaaggaaa agaatattac aattaagatg ccagcaggag ttccagtaga ggtttcaaat
    56941 tcatttactg cattattacc gacagcagta attttaatgt tattctgggt aataagacat
    57001 attttaggat ttgatataag tgttgcacta agcgctatgt tatcaccttt aaaaggattc
    57061 ttatcaggaa atagtttagg tggtgggtta ctgacagtat tcctaataac tttattctgg
    57121 gtacttggaa tacatggtcc agctataatg gggccagtaa taagacctat atgggacatg
    57181 tctatagcag aaaatataac tgcattcaca gaaggagtat cagctcatgc aatgccaaac
    57241 atatttacag aacaattttt acagtggtat gtatggatag ggggagcagg ggctactctt
    57301 gcattagttg taatgtttat gttttctaag tcacaatatc taaaaagttt aggtagatta
    57361 ggatttttac cagggttatt caacataaat gaacctataa tatttggagc accaatagtt
    57421 atgaatccaa tactagggat accatttata attggaccta taataatgac aattctatca
    57481 tatgttctta ctattacagg ggttatacct atgatggtag caagattacc atttgcaatg
    57541 ccagcaccaa tagcagcagt aatgagtact aactggagta tactagcggg tatcttagta
    57601 ttaatcaact ttgtgatatc atttgctgtt tattatccat tcttcaaagt ttttgaaaaa
    57661 caacaattac aaagagaaca agaagaaatg agtgaaaatt tataaaaata catagatata
    57721 gaggttttgt actatataaa atatagaaaa agcttataag ttattaaggg tgaaggtagg
    57781 aggaatgacc tttgccttta attttatata ttttaaataa tgtaatttga ggaggagaaa
    57841 gatggaaaga agattaggaa tatcagtata tccagagcat agtaacatgg aagatgataa
    57901 ggcatatata aaaatggctt caaaatacgg atttaaaaga atatttatgt gcatgctttc
    57961 aattacaaga cctaaggaag aagttaaaaa acattttaaa gagattataa cctatgcaag
    58021 agaattagga tttgaagtaa tccttgatat agctccaaac atatttgata tattacaaat
    58081 atcttatgat gatttaacat tttttagtga gttaaatgct agtggaataa ggcttgacta
    58141 tggatatgat ggaagtaaag aagctatgat ttctttcaat ccatatgatt taaaagtgga
    58201 actaaatatg agtaatgatg tagcatactt ggataatata attacttaca agccaaatgt
    58261 aaataatata tatggttgtc acaattttta tcctcaaagg ggtacaggct tgccatatga
    58321 tttttttgta agatgttcaa atagatttaa aaagtatgga ataagaactg ctgcttttgt
    58381 taattcaaaa tatgcaacaa tcggaccttg gaatataaat gatggactgt gtacgcttga
    58441 aatgcataga aacttagata ttgctacagc aactaagcac ttattcgcaa caggattgat
    58501 tgatgatgta attgtaggaa atgcatatgc aagtgaagat gaattaaaaa gaatgtctga
    58561 agtaaatgaa taccaagttg tatttaatgt agtagctgaa gaaaaaactt ctgaagtaga
    58621 aaagataata atggtaaatg agcaacactt tagaagagga gatataacca accaagtagc
    58681 aagatctaca gaagtaagaa aaaaatatgc taaagaaaat ttccctaagc atgataatat
    58741 gaccatcttt aaaagaggag atgtagtgat tggtaatgat gactttggaa agtataaagg
    58801 ggaattacag ttgatacttc aagattgtgc agatgaaaga aaaaataagg taggtagaat
    58861 aaagaaagac gaaataatgc ttttagactt tattgaacct tggagtaaat ttaaacttat
    58921 tttagaggga gagtaaagtg aagatagaca tattaataaa aggtggaaaa acagtagata
    58981 aaagtataat tgatatagct atattagacg ataaaataat agaagtaaaa aatcagatag
    59041 atgattctaa gtatcaggca aatcaaatta taaacctaga tggagaaaaa tttattagtg
    59101 ctggttggat agatatacat acgcactgct acgaaagact agacctttat aaggattatc
    59161 cagatgaggt tggaataaaa agtggagtta ctactgtagt agatgcagga acaacaggag
    59221 ctttagatat aggtgaattt tatgaagata ctaaaaaata taaaacaaat gtatatgctt
    59281 taataaatat tgctaagcag ggaataacat ctcaagatga actttcaagt atgatgaata
    59341 ttgatgaata tgaacttaaa agagcagtta aaaaatacaa agattttgtt gttggaatca
    59401 aagctagaat gagtaaaagt gttgtaattt caaatgatgt tgaaccttta aaagtagcta
    59461 aaaaaataaa aaatgaactt aatctaccta tgatggttca ctttgggagt tctcctccaa
    59521 cgatagagga tatatttgac tatatggaaa aaggagatat attaacccat atatataatg
    59581 gaaagccaaa tggaatactt agaggcaatg aggttaaaaa ggaaatcata gaagctagag
    59641 aaagaggtat aattcttgat gtaggtcatg gaaccgaaag ttttagtatg gatattgcaa
    59701 tgaaatctaa ggatgcagga atttttccag acactataag tacagatata tatattaaaa
    59761 atagaataaa tggtccagtg tataatctat ctacaacaat ggaaaagttt atatatatgg
    59821 gctattcact tgaagatata atagataaag ttactaaaaa tgcagcagat gcaataagtt
    59881 taaaaaataa aggtttaata aaagaaggat atgatgctga tttaactata tttgatgtgg
    59941 ttaatgaaga aaaagaactt caagattctt tgaataagtc agtaatcaca agtacgtcta
    60001 taaagccaag agcagtagta gtcaatggag aatatttaaa tataggtaag tctataggag
    60061 agaatgagta gaagggagaa actattgtat gagtagtata tttgaaaaat actctgtaag
    60121 acgtgttata aatgcttcag gcaaaatgac tatactagga gtatcaacag tagataagga
    60181 agttattgaa gcaataggtg aagggtgtaa aaatttcttt ataatagaag aacttataaa
    60241 taaaacaggt gaatatatag caaatttatt agggtgtgaa agtgcactaa tagtttctag
    60301 tgcatctgct gggattgcac agagtgtggg agcaatgata gcaaaagatg atatgagtct
    60361 agtttacaat gtaaataatc ctaagaaaca agttaaaagg gaaataataa ttccaaaggg
    60421 acataatgtt gattatggag ttccagtaga agtaatgata agacttggag gaggagaagt
    60481 tgttgaggcc ggttatgcta atatgtgtaa caaggaacat ataataagag agataaatga
    60541 aaatacagca gcaattatgt atattaaatc tcatcattgt gttcaaaaga gtatgctaag
    60601 tgtattagat gcagtacaag ttgctaaaga atataattta cctttgatag tagatgcagc
    60661 agcagaagaa gatttaaatg tatattatga attgggagca gacctagtga tatacagtgg
    60721 tgctaaggct atagagggtc ctagctcagg gttagtaata ggtaagaaaa aatacataga
    60781 taatgtaaag cttcaatcaa agggtatagg aagagctatg aaaataggaa aagaaaatat
    60841 tgtaggtcta acatgtgcaa ttgagagata tataagtaat gataaagtaa ctttaaaaga
    60901 aatggaggac aagctaaatc catttataga caagataaat actataaagg gagtgagtgc
    60961 tagtataact agggattcag caggtagaga aatacttcgt ggagaaattg actttaatga
    61021 agatataata aataagtcaa cacaacaaat tataaatgaa cttagaagtg gagagatagc
    61081 tatatacact agagactata aggctaatga aggcaagatt gagattgata taagaagtgt
    61141 aactggaagt gatttagata ctatttataa taggataaaa aatatagtag aaagttagag
    61201 tgtagagtaa gtgacattat aatgatttaa taaattaaat tttaccaatg gaggggataa
    61261 atatgaattg tataccacaa tattataaaa atagagtttg tttaaatgtt cttgcaggaa
    61321 gcataaaaaa tgctaaagaa gtatatgatg cttgtgacgg gcatgtattg ataggagtac
    61381 tatcaaagaa ttacagtact gtagaagcag ctattgaaga tatgaaaaaa tactcaaagg
    61441 aaatagataa tgcaatatct gtggggcttg gagctggaga cccaaatcag tcaaatatgg
    61501 tatctcagat ttctaaagaa cttcagccac aacatataaa tcaagtgttt acaggtgtgg
    61561 ctacgtctag agcattactt ggtcaaaatg atagtataat aaatggatta gtttctccaa
    61621 ctggtaaacc aggatttgta aaaatatcca caggtccatt aagttcaaaa gaaaaagatg
    61681 gtatagttcc tatagaaaca gcaatagcta tgatgaaaga tatgggagga agctcaatta
    61741 agttttttcc aatgggagga cttaaaacaa aggatgaata tatagaagtt gcaaaagctt
    61801 gtgcaaagca taatttttat ttagaaccaa caggaggtat agacttagat aacttcaaag
    61861 agatagttca aattgcactt gatgctggtg tagaaaaagt tatacctcat gtttatacat
    61921 caataattga taaagaaaca ggtgaaacga aagtggaaga tataggagta ctttataaaa
    61981 taatgaaaga attattggga tagatttatg aatatattag cttttggtga aataatgatg
    62041 agactttcag tacctgacta caagttctta acacaaacca atgaactaaa ttatataatt
    62101 acaggcacgg gattaaatat attatctgga cttaaaaact ttggatacaa tacctatatg
    62161 ttgacaaagt tgcctaataa taatgtaggt aaagcatcaa gtgcaaatat aagaaagctt
    62221 ggagtaaaag atgactttat cacatatgga gggaatcata taggagtgta ttttcttgaa
    62281 aatgggtatg gagaaagacc ttctgaagtg acttatttga ataggttaaa tagttcattt
    62341 tgtgagagta aattacaaga ttatgatatt gataaatgtt tagaaggaat ggatatagtc
    62401 catatttgtg gtattgctat gcaacttaca gattcagtta aagagattgc tttagaacta
    62461 gctagaaaat cttatgaaaa ggggataaaa gtattctttg attttaattt tagacaatca
    62521 ttaaatccag aaaggactta tgatgattta gtaaatgatt ataagaaaat actaccatat
    62581 tgtcatggtc tatttgctag ttatagagat ataaataaga tacttaatat agatagtcta
    62641 aatataaaat ctagttcaga attgattaaa aaagagtatg atataggtat tgtagctgga
    62701 actatgagaa gatttgatga tatgaataat agatttataa agggatatat atcaaatgat
    62761 gatggttatt ttgaaagtag ggagtataag ttagaaatat atgacagggt tggtgccgga
    62821 gatggatatg tagcaggaat tatatattca tatttggaaa atatgaagag tgaagatata
    62881 gttgagtttg gggttgctag ttcggtgtta gctcatacaa cttatgggga taattcttta
    62941 gtaagcacag gtcatgtact tagactgatg aacaatgaaa aaatagatat attgagataa
    63001 tacatttgta tataataaaa tttttatctt ttttagacac atttttgact tgcttatatt
    63061 tgttaaacag agttattttt aacgattata aatattaaat taaaagttaa ataataaaat
    63121 agtagaaaat agcattaact atagaaaaaa tggttaatgc tatttttatc gctaatattg
    63181 attaatttta tattatagaa atgaactttt ctaatgctgg atttgtattt tttttattcc
    63241 atacaactac aacttcaatt ctattttcta cttcttttat aggtactatt gcaatatcac
    63301 gttctatcat tgtatctgta acacaaaatg aaggtaaaat ggatattccc atgttagaag
    63361 ataccaatga ttcaatagta ttaagattat ttgaacgttg taccacatta ggtacaaacc
    63421 ctgcttcacg atatctattt tgtatcatag atttttgtcc atactcatcc cctgtttcct
    63481 ttacaaaaat aaatttatca tgttgtaatt caattaaatc gatagaatcc tcattgtaaa
    63541 gtgtatgacc aggaggtaaa agagctacca aagaatatct ttctacagtt ttatattcaa
    63601 aatcttttaa tggttgattt tctggattaa taacaaaagc gaggtccata gaattatttt
    63661 ttactaagtt taaaagttcg gttatctcat tagtacaaat atccatagat atattagggt
    63721 atgtattaga aaattctttt aaatattgtt gaagtttgtt tttttcgtat cctattaagg
    63781 ttccaatgct caaagttcca aaaaaaccat gtgcaaattg ttgtgttttt gcaatagcat
    63841 cattgatatt ttttattata gtacgtgcct cagataaaaa aacttttcca gctggtgtta
    63901 gttcaacatg acgtttactt cttgtaaata gagttacatt tatttgttct tctaaagctt
    63961 ttatttgctg tgtaacagcc gtttgagaaa tataaaattt ttctgctgtt tttgtaaaac
    64021 ttagattttc tgctacagat ataaaatatt ctaattgttt agtattcaaa taatcacccc
    64081 tatttaaact tgattgtttg taaaccttat ttatctataa ttaaagctta ttatagtata
    64141 agaaaattta cttttaaaga atattagaaa atatttgtat aaaaatatat gttttaagta
    64201 tatctttaca ttagatttta taaatttatt aataagaata acttatatat tccaatgaaa
    64261 acgatattgg atttaagtaa gtttgtctca taaaatgaaa gtatatcaat tgataatact
    64321 ttaaataaga agggagaaaa aatggaagat aaattttatg caaaaggcaa cggaaataac
    64381 ggatatatta aaaatcttga agtttgttcc tttaataact tagatggaac ttgtggaatg
    64441 tttcaaatgg ctctgtacaa aagagatgaa aaatactatt tatatggatg ctgttttgga
    64501 ggaaataaaa aaaatggagt aatgattagc gatattacag acccttataa tccacaattt
    64561 ataaaacatt ttcaaatgtt agaccctaaa gagtatccta caacaacaac tcccaaaatt
    64621 caaatagcag atgatttaat gatagtagca atgagttgtg gaagtgggcc aggagcactt
    64681 gttgaccaag ctaaattagc aaatattaag tgtgaagcag gaattagaat atacagttta
    64741 aaagaagacc ctttaaatcc taagttttta ggatattggg attgtggctt aaagcatgta
    64801 atgggtgttc atagattcat gtacaatggt ggaagatatg tacatttatc aagtgattgt
    64861 gttggctttg aaggtcttat ttatagggtc atagatataa taaatcctac taatccagtg
    64921 gaaataggta aatggtggag accagaccaa tatgcagatg gatatccaaa tagaactttt
    64981 gatgcaggag cacctcattg cccagaattt atggataaag gatggcttca tggacctcca
    65041 tttgtaagag acggaaaagc atattgtggt tatggaggag ctggtttagt tgtattagat
    65101 gttgaagatt taacaagacc aagatgctta ggtgaattgc catttacgcc tgcattttct
    65161 agtagacttg caggtgcaag aactcataca gcattaccat tgccaggaag agatttagtc
    65221 gttgttcaaa atgagggaga aagattccag ttctttaaac cagataacat tacagatgtt
    65281 caagctatga ataatataca tatggttgat gttagtgacc caacaaaacc aacattaatt
    65341 gctcaatttc catatcctga agttccaaaa gattttcctt atcctaactt taatgttgca
    65401 ggattaggaa aaccagggcc atttggtcca cataatcttc atgaaccaat ggataataaa
    65461 ccatggttag agcaaagagg agatagagta tattgctgtt atttccatgc agggctaagg
    65521 gtttatgatg tatcagaccc atattatatc aaagagctag catattttat accaccaaat
    65581 ccaaataaaa caccagaaga atcttatttc ccaggattcc caggaccacg cttggcagta
    65641 acagaagatc ttatcgttga tgatagaggc tacatcatca tagatgcttt agatgatgga
    65701 ttctatatat taaaaatgaa agaagattaa ataaatacta aagagggaga gttgaaaatg
    65761 aaaatactag gtatttcttt tggaacaaaa aatggaaata atgacacaat gtgtaaagtt
    65821 gcacttaaag gtgccaaaga agcaggggct gaagtagaat ttattcaaat gtcatctatt
    65881 aacattaaac attgtactgg atgttgtgcg tgtgttaaaa ctttattatc tgggaaaggt
    65941 agtatgtgtg tattaaaaga tgattttgaa tggttgcttg acaaaatgaa agatgcagat
    66001 ggtatagtag tttcagaccc tatttttgaa gaaggggcat caggattatt ccatactata
    66061 atggaccgtt ttggccccag agcagataga ggaaataaca ttataggaac aaaagttgca
    66121 gaagctatag gaggaaaaat tccagattca agaatgctta atgataaagt aatatcattt
    66181 atgggaatag gaggttctga ctggggtaca agagttcaat gtgaacatgc tatgctagct
    66241 ctcataccaa tgtggaaagt tatagataat gcttggttcc catgggcaaa ggaattagta
    66301 atggatgata caaggcttgt tcaagttcat caaattggtt taaatatagt tgaagcagca
    66361 aaagattttg aaaaagcttc atatcaagga gaagaaggtg tatgtccaca ttgccacaat
    66421 agattattct accttgagcc aggtactaaa aaggcaattt gtgctctatg tggtatagtt
    66481 ggagagttag atactataag tggaaaaact atatttagtt ttccagaaga gcaattaggt
    66541 catgctcatg atactttacc aggtaagttt atacatggtg atgatattaa gaaaatggaa
    66601 ggtcattatg cagaagttcg taaaacacaa gaatttaaag aaagaaaaac atcttataat
    66661 tttatagagc cattaactaa agaaaagcaa gctggagttt cattaagata ataattaaaa
    66721 tactaagact cttttttaag gtatgttaga tgttatagga ggcttattgt atgaatgaaa
    66781 agtcaagttt taaacaaatt gaaattattt tagcagttat ttttttggta cttacatatt
    66841 acaaggttag attaactcca gcatttattg ttatatttat accactatat ttaagttatt
    66901 ttgcagtatc tatgattgta aatcaaatag caattaagct attggagata aggcaagcta
    66961 gggaagctac taattacaat ataggaaatg gatagaaaga aaaaagaaat attaacactg
    67021 tctatgggga ttgctttact acctccttta tgggcagtat tagcacctta tataggaata
    67081 aaaactggag ctgtagcact aatctgtgca ggattatatg taactaatgg taataaacaa
    67141 aaagatggat taaaaataat gtttggtttt tggtgtggag atttatgggc agtgttagcc
    67201 attttaatta tgggatatat gaatttcaat caaaacctag aattattttt aacacttagt
    67261 atattaggtt tttttgcagt tgtaattgca tccttatttg aaaaaataat tttcctacca
    67321 tcatggcttt gtggttgggc tataggtcta actattatga caggtgaaaa tattattaat
    67381 ttacaagata tttgtattca aattgctgta gctatggcag taggagtatg gtacgtgggt
    67441 gcaggtgtag atttgtttac aatatatatt ttgagtaaag ataggaaaaa gggaaattga
    67501 aagcatgtga atatactttg attataggag aatggctatg gggtttgaat ttaaaataat
    67561 gagaagttta atatatgtag gacttgccaa ggaagaatat agacctaagc taatggactg
    67621 gttatatcgt caccatattc cagatagtat tagcactttt ggaccatatt gtactaaata
    67681 tgccttttat caagcatatc ctacaccaaa tgaaggtgag cgttttggtg cacgtaagat
    67741 gcaactaaca gaacattatt ggcttgtaga tgaacatatg cctgagatgg caaatagaat
    67801 tatgacagaa tatatgccta tggatgttct acgttggcaa gggtgtatac cagatgtaga
    67861 aaataaaagg gttcatgaaa atgcagaaag tggagatgca ggacgtgcag taggtggaga
    67921 taatggatgt ccaccattta tatttgcctt tgttccaata aactgggaag aagactttag
    67981 aggaaaagga cgtactgtac aagatggacc aaactatcgt tggcaattta tgattaagta
    68041 tccagatggt atctctaaag aagaaggaga aaaatggttc tatgatgagg tagtgccata
    68101 ctttacaaac tgttgctatg ttaatcgttt tgtcagtagt aaaataatga ttaattatgg
    68161 agcaactgct tttgaccgtg tgtcagaact atggtttgaa ggggaagaag aatggtataa
    68221 agctgtggtt gaagagacaa agtcgtttat taaaaaacca gaatgggcac aagaagagga
    68281 gttcccatat ttaaaaccac aattcaatat cgcatcagta ttcttaggtg atatagcaac
    68341 tatggatgca tactcacagt atcgtggata tataccaatg agataaaaat tatagtttat
    68401 gataagtaga ggaggcattt actcttactg gtagaagaag acttattgta tccttaaaag
    68461 taggtgaata tatagtttta tatttaaatt tatataaaac taagactaat aaatatgaaa
    68521 caatagaatt agaataattt gataatattt gttaaaagag catttagaat gtgtttaaag
    68581 attaagatat tccttttatg gtagcagata gttgaaataa taaaactgtt atcatgaaag
    68641 gaatattttt atgtatagga aatttttaaa aataaaagtt aaatatgttt aagaacatct
    68701 taaagtgaaa gaatcattgt tagaaatatg tagacaatat agtctttata acgtatcata
    68761 ttaacaagtt tacacttgga ttatgaaata aaaagagtaa ttccaaaggt tgtaaatact
    68821 atgctgactt tgatacttca aagtttaggt gattttgtaa ttgttaatag aaatacgttt
    68881 aatgagcata aagaatttat ctaataatag gagaatataa tgtatacaat tggacaagta
    68941 tctaaatttt taggaatatc tagagataca ctaaaatttt atgaggacaa aggattagta
    69001 aatcctaaga aaaatgatga aaatggatat agaatatata atcaggttga tatctatgat
    69061 attgcaacaa taaactttta tagagaaatt gatatagaaa ttaaaaagat tcaagaaata
    69121 agaaaaagta agagtataaa caatttagaa ctcttactag aagagaagga acaaatcata
    69181 ctaaaagaga tagaatataa aaagcttctc ttaaaaaagg ttcagttagt caaagaagat
    69241 tgtgacaaaa taaaaacata ttttggaaaa tacacaataa aagaaatgaa gcctttggaa
    69301 gtaaaaggta aaataaaaca tgttactaac tatgaggaat atgaagccct aaaagagaat
    69361 acaaacaact taaaaaaagc agttacatta actgatttaa gaagagtaat aaattttaat
    69421 gaagaaggta taatagaaga aaaatttata attgtaaggg aagtagatga ctacaacaaa
    69481 atcatagaag gtgaagttct atctcatccc aattgtattt atactattat tgaagatggc
    69541 agatggtcaa ctggaggaga aaatattgat aataaagtgg aagacagatt aagagaaata
    69601 gcaatagaaa atgaatgtga attacttgga atagtctatg ttaatatatt gcttactact
    69661 tatgaagaag ggattgagcg tatattttta gagatttatg cacctataaa ataatataaa
    69721 agcattgacc tgggacttac tcataggttt aaactcatga tataagcagt tataacttat
    69781 atagcaatta aatattaatt tgaaatgagg attacttatg agaacagaga aatcattaaa
    69841 aaggcctata gccagtttta ttattctaac aaatataatt tttttaccac tttttttatt
    69901 ggtagtagtg actataatgt taaaacttcc aacagtgata tctgacattg cattgtgtat
    69961 atcagcgtgg tcatccactt ttgcatttat gatattattt aaaaaaattt atccaggtaa
    70021 gaaattttta gtacacgtaa aagatagatt tagaaataaa cttaaatttt caacagtatc
    70081 tataataatt agtatacaag tcctaatagc tgtagtagtt atatttatat tagcatctaa
    70141 aaatcatgga ataatgccta actttacagt ttcatcatgg ggggcattta tatatttatt
    70201 tttaaaaaat ttatttgcag gatcattagg tgaggaatta ggttggagag gatttgttca
    70261 aaatcatctt cagaaaagac attctccttt aaaagcatcc ataatagtag gtttttggtg
    70321 ggggatgtgg catttaccaa tatggtttac aacaggattc aaaggacttg atttaataaa
    70381 atatattata ttttttatga ttgcaattat atcaatcagt attataatga caacttttta
    70441 taatctaaat aaaactttga taatacctat tgtaatacat caactattta attttttaat
    70501 agggataatt aatggagatt taatagagct tataaattac tatgcaatgt tatatttaat
    70561 atttgcaatt gcattaatag ttataaatcc aggaaatgta ttatataaaa atattagaga
    70621 gtaatatata tctttatggt aagatataaa gaaattatta gaagaacatc caaggaggaa
    70681 taaacatggt tttactgatt gttgatgcac aaaagttaat aacaaacgag aggttatata
    70741 aatttaatga atttgtagta aatgtagaaa atttaattga tacagctaga aaaaataata
    70801 tagaagtaat atatgtacgt catgatgatg gagttgaaaa tgaattgact aaaggtaaaa
    70861 atggctttga aatatacgaa aaatttaaac catgtaatgg agaaaaaata tttgataaaa
    70921 aagtaaatag tgcttttaaa gaaactggtc tattagaata cctaacaaat aatggtgaaa
    70981 aagatattat tattgctggt ctccaaacag attattgtat tgatgccact ataaaatgtg
    71041 gatttgaaca tggatttaat ataatagttc cagcttattc aaatacaact gttgacaatt
    71101 tttttatgtc agcagaacaa tcatataaat actacaatga atttatatgg aatgaaagat
    71161 atgcgaagtg tatttcatta gaggaaacac ttagaaaaat gaaataaaaa tagagtatga
    71221 attgtatatg tacataagtt gatttcataa aaaaggatgt taaattccaa gttaaaaatt
    71281 agattaaata tattatatta tagataaggc acatcaattt tattttaaat taatgtgctt
    71341 tttaattgta gtaatttatt tataatcaat atgattttta ttatttaaat caatttttct
    71401 tgagtttctt tgtctaaaga aacttttttt atttataaaa tctacagtta tattatagta
    71461 tctattttag agaagtttaa tttttgtatc aatctaaaac aaaagttata cttaaatgaa
    71521 attgaaaacg ataaaattct caaataaaat aagtattgtg gaggtgatga aagaatccaa
    71581 tgataatatg aagactaatc ttaataagaa agtaggggtt aatggtagtg gacaaagaaa
    71641 ttgtatcaat tctccagatt ttattaaata gcacattgat tacaactaat ggattacaag
    71701 aggagtttaa ttcatcaaag agacaaatta cttatagaat aaataaaatc aatgacatgc
    71761 ttaaagtaaa aaatgtacca cttatatgtt taagagctga taaagatatt atcgttagaa
    71821 aagaaacaaa aaaagcaatt aaagaaattt tagaaaaaaa ctattctaag aatacttatt
    71881 attttagtaa gacagaaaga cttttatata tgtatttaat gctttttatt aacatggagg
    71941 atatttcaat taatcatttt ataaattcta taaaagtaag taggtctact gtaaatcttg
    72001 atttcaagga tttgatacca gagcttgaaa agaagaacat taaagttaag aacaatcgta
    72061 taaatggata ttacatagtt ggcaatgaga tggaaattag gagagtactt attaaaaaca
    72121 ttatagaaac tttgtctaat gagaaaagtt caagagtatt tgatattttt attaaagaat
    72181 ataatttaga tagttttgaa gaggctaaaa aaattatatt aaagctaata aaaaaatatg
    72241 aaattacttt tgttgaagat agattagtag aatttatata tatatttatc tttctaaagg
    72301 caaggatgta ttcaactaga atagttactc aggaaaatgt agatattcct aatatttcgg
    72361 ttatgagttc aatgaaggag tataaatttg ctaaggaatt attagaagta tatgggagtg
    72421 aagataagat aaagcctcac aatataatgt atattagtgc ttggatttta ggtatatcag
    72481 taggaaatta tgaagaagat acagaagata aggatgtaat ttcaaaaatt gtaaataaaa
    72541 tgatgacaaa gtttggatat ttaagcggag tttactatat aagccaagaa aaaatattta
    72601 aacaattata ttctcatttt agacctgcct actatagact tttatttaaa ttacctattt
    72661 ataatccgat ttgtgaaaaa gtaaaagaag aatataaatt agtttataga attgtaagta
    72721 atgcaatgaa agagttttgc ggattatttg gagaagaaat tcaggaagaa gagttagcat
    72781 atcttacaat gcactttgca acactttttt caaataaaaa agaatttgat ggttttagaa
    72841 aaagaatagc attaatagtt tgttcaaatg gcgttggtag ttcagctatt ttacatgcag
    72901 aacttacaaa cttatttcct gacttacact ttataccaat gtcggaatca gttggattag
    72961 aaaatataag tgaacctgta gatattgtat ttactactaa ttataacgca gagggtttaa
    73021 aaacagatgt accagtaatt aaagtaagcc ctgttatgac cacaaaagaa aaatataaga
    73081 ttacacgtga agtgtatatt caattaggtg atatttattt aagacaacct aaaatagatg
    73141 aggttatgga tataataaaa aaatatgcaa atgtaacctc tgaaagtatt ctttcaagtg
    73201 agctattagc ttattttaca cagatagaga attttacatc taaggaagga gaggggccta
    73261 tgctaagtga gattactaat gaaacactag taaaaataaa ggtaaaagct aagaattggg
    73321 aggaagctat tagacagtca gcttctgtat tagttgaaaa taacaaagta actgaagggt
    73381 atgtagatgc tatgattaac tcagcaaaag catctggacc atacatagta attacaaaac
    73441 atgttgcact tccacatgct agaccagaag ctgggtcaaa agagattgca ataggcattg
    73501 ctactttaga tagtcctatt gagtttggga ataacgaaaa cgaccctgta aaatatgtat
    73561 tttgtctaag tgcaatagac aataatagcc atttacgtgc tatgtctgag ctagttgaac
    73621 tattggaaga agatgagttt tttaaggttt tagatagtgc taaagaagct aaagaaatta
    73681 ttgattttat aaaaacacac gaattataaa ggaggattta attatgtata aaattttaat
    73741 cgcatgtaga gcaggagttg gctcaagttt aatgttaaaa ataaagactc aacaaattat
    73801 taaggaaaat aactttccaa ttgaagtaga acatggttca ttagattcgc taaatggatt
    73861 caatggagat gctgtagaaa cattaattga tgttgctgaa gaattaaaaa ataaaaattt
    73921 gaagtttgat ataattggga ttcacaatat tgttgaccgt aatgaaataa agacagcact
    73981 agaaaaattc cttgcttcaa aagagggata aatttaagat gataaggagg aatatttatg
    74041 gagtttatta ttagtttgct gagtacacct gctgttttgc ttggcgtagt tgcatgtata
    74101 ggattgattc ttcaaaagaa atcagctgtt gaagtattta caggctcttc aaaaacactt
    74161 atcggttttt tgatatttgg tattggtgcc tctgctatga caggagcact tcaaaatttc
    74221 aataaactgt tccaacatgg ctttggaatt actggtgtta tagcttcacc agaagcagct
    74281 acagcacttg cacaaggtac atatggtttt gcagtttcat gtacattaat tcttggattc
    74341 atattaaatt tagtatttgc acgtattaca aagtttaaga atattttctt tacaacaggt
    74401 catagtttgt tcttttcttg tgtattagtt ttaattatga aagcacatgg atttgataat
    74461 acaatcacta ttttaatagg aggaactatc ttagggttta tgtctgctgc actacctcaa
    74521 ttctgtcaac catttatgcg tgaattaaca ggtggcgacg aacaagctat tggtcacttt
    74581 aacatgattg gttatggttt atcaggttat attgggcgtt tattttcaaa acataaagat
    74641 gatacaacag agactataga atttcctaag tggttatcaa tattcagaga cttcttaatg
    74701 ggtctatcca tagttatgtt aatcttattt tatattgcaa cattaaaagc tggtcaagca
    74761 tttactcaag aaattgctgg ttcaacacat tggttggttt ttccgcttat agaggcattt
    74821 acatttgtgg caggtatgtc aatattgatg tcaggagttc gtatgttctt agctgaaata
    74881 actgcagcat ttgtaatcat ttcagaaaag tatattccag gttcacgtcc tgcgctagat
    74941 gttccaaccg tatttccata tgcaccaaat gcagttatta ttgggtttat atcagcatat
    75001 gctgctggtc tattagcaat tgctattatg gcatcatttc ctagtatatt tcctgtagta
    75061 attattccag ctgctcacat atgttttttc tcaggaggta cagctgcaat atttggcaat
    75121 acttcaggag gatggagagg ggctattgct gggtcatttg ttgtggggtt attacttgca
    75181 tttttgccag ttatactata tccagtttat ggcactcttg gtatagaagg agcaactttc
    75241 cctaatattg attacaatgt agttggttcg atattacata atattttaca atttataaaa
    75301 cctatttaaa ctaaattata taaaagtata gtcatagtta ctatgatttc aaggaggata
    75361 catcttatgg aaaatacatt atctgaattt ttagataata tatctaatga attgtcagaa
    75421 tttattgcct caatagatga gacatctata aataaagcat gcgaattaat tcttgaagct
    75481 gaaaaaaatc acggacgtgt acatgtgact ggtattggca aaccaggaca tgtatcggga
    75541 tatatttcat cattgctttc atctactgga acgtcagcat atatattgca tggtacagaa
    75601 gcagtacatg ggtcaagtgg tcaagtagtt gaaggagatg ttgttattgc aatatcaaat
    75661 agtggtgaaa ctcaagagtt aaaagcaact cttaagactc taaaagtaaa tggagcaaag
    75721 ataattggtg taagtggtaa tgagagttca tttttaaaaa atatttctga tatattcctg
    75781 tttgcaggtg ttaaacagga aggagattgt cttaataaag ctcctcgtgc ttcaatttta
    75841 gctgaaacaa taatattaca atcattaagt gttgtattac aatatgctaa aggtcttaat
    75901 acacagcagt atttgaagtg gcatccagca ggaagtcttg gaaagtctat tagagaggga
    75961 atataatttt atgaaatata aagggattat atgtgcaatg ataacaccat ttgatgaaaa
    76021 tcaaaatatt aattcacaag caacatgtca attaattgat tatttgattg aaaagggaat
    76081 ttatggatta tttattttgg gcactaatgg tgaatgtcat gtattaacag atgatgaaaa
    76141 agttgaattt gcaaagattg ttattaatca tacaaataat cgtgtacctg tttttgttgg
    76201 aacagggggt aattcaactc gtgaagttgt agatttatct aagagaatgg aagcgattgg
    76261 agcaagtgca ttatctatta ttacaccata ctttgttaca ccaacacaac aggaattaat
    76321 cttacattac aaaactattg ctaattcagt taatttacct attataatgt ataatatgcc
    76381 aggtaagact ggaattaata ttgaaccaga gtcagtacgt gaattatcaa agataaagaa
    76441 tattgttgga attaaggata gtagtggtaa acttgacaac atgaaatctt atattgaagc
    76501 aacgaagaat gagaatttta gtgtgttttc aggctcagat tcacttattc tggatagtct
    76561 aaaagctggt agtcaaggag ctgttgcagc aacaacaaac ttcctcacag agattggtat
    76621 ctctatctat gaaaacttta tgaaagggga tttggaagaa gctcaaaaag ctcaaagtag
    76681 tatagaagaa cttcgacgta tactgaaact tggaacaatt ccatctgtta tgaagaaaac
    76741 tattgtcttg aatggaatta atgttggaac tgcacgactt cctgtaactg aaccaactgg
    76801 ggaagtactt gaagaaatta aacgagtagt tgaaaattat aggacaatac ttaataaaag
    76861 tagtgagaat agataatata aatagggaaa ttacactggt atataattaa tatatatatt
    76921 ataaaacatg actaaaatta atgaataagt aaagtggttt gatgagtata gaggtgataa
    76981 tatgaaaaag atgaatataa ccaaaagaat gtcagaatgt ggggctcttg caattgtaag
    77041 agaagaaaat cttaaccgtg catgtgaaat tgctgaagga tgtataaaag gtggtataac
    77101 agttatagaa atgagttata ccctaaataa tgctggagaa ataattcaag ggcttaataa
    77161 aaagtatggt gaaacacttt gtgtgggagc aggaacagtt ttggatagtg aaacagctcg
    77221 tcatgctata ttacatggag ctcaatttat tattgcacca aattacaatg aaggtgtagc
    77281 gaagatttgc aatagatatc agattcctta tgctccagga tgtacatcat tgactgaggc
    77341 agtagatgca ctaagtttag gagcaacttt tataaaagct ttcccaatat cagatttcta
    77401 tggacctaaa ctagtaaagg tatttaagac accaatacct gatatgccag ttttagcaag
    77461 tggagggatt aatattgaaa acctacatat atggttagaa aatggagttg atgtatgtgg
    77521 atttggtggt ttattaacta aaggttctgt tgaagatatt gctaaaaatg ctaacaagat
    77581 tcgtgaaatc attaaaaata taagaaaaat ttaacatagg gctgtatcat agtatcttat
    77641 aattactatg atacagcctt tttaatatta ttcaaattta aaacagttta catttctatt
    77701 atattacata taatttcagt aattttatat taatttttct atctggaaaa aaatgattta
    77761 aaacttaagt tatgatataa tttcattaaa agaaggcgat ttttagtaaa tatgagaaaa
    77821 taatgtgttt ttaggggaaa agttaaatac agatttaagt gaacaagaat cgataattaa
    77881 gatattaaat ggtgaatagg gcatcaaaaa aattactaaa ttaaaagttt tagagggaga
    77941 atcttagcaa gtgtgtgtga aaattcaatt tcaaacaaaa aataattgta aatgaaatca
    78001 atttatacac gttgaagatt cacttttatc attatattaa aaagcagagt gaattaaaag
    78061 tgagtctaaa gataggagga taattaaaac aatgaaagaa gacattaggt tacatcgaat
    78121 gtgtaaaaaa gaacaagcaa caaagaatga agttatatca gaggatattc taaaatctat
    78181 gagtattggg gtcagtaaac attttttaga tgattcattt acaataatat ggggaaatac
    78241 atcattctat caattattag gatatacaga agaagaattt ttagttaaat tttctagttt
    78301 aaaagattat tatgaacaga atctttatca ttttgaatct atgaaaaatc attttttaga
    78361 ggcttatcat catggcgaaa agagtataga atatcaaatt tgcatttcag caaataatgg
    78421 agatcctgtt tgggtaataa tgactggtat attaattgaa tcacaagata atgagaaatc
    78481 aatggtctat atattgtatt caaaaattaa tgagttaaaa ataaagcaag aagaactatc
    78541 tgatatggaa aaagagagta cagagaattt taaatggatg atgtcagagt atgctgggaa
    78601 tgtttatatt agcgatatgg atacatatga attactatac ttaaataagc actcatgcaa
    78661 tactttacag gcatcagcaa atgaacttat tggaagaaaa tgttatgagg taattcaagg
    78721 tagaacttcg ccatgtccgt tttgtacaaa ttcgtattta aaaaaagatg acacatatga
    78781 atgggaattt tataataaaa aactgaaacg aacatttata attaaagacc gtatgttgaa
    78841 ttggcaaggg cgaagagttc gtattgaatt atcttatgat atgtatagtg ctgaatataa
    78901 attagcaaaa aaagatcagg aaagagaatc aattttgaaa actattccag caggaatggt
    78961 tagattagat gcaagagatt atcttactat actttggtgt aatgatatat ttttgaatat
    79021 gattgaatat acaaaggaac agtttgcaga ggaacttaat aatcaatgtg gatatttatt
    79081 ttctgaagat tataaacgta gtaagaaact ggcacaagat ttgaaggagt ctggggataa
    79141 tgttgtattt gaagcaaaaa tatatacacg ttcaagggaa gaacgtatat ggactgttac
    79201 attgtgttat atcagtgggg aagacagttg ggatggaata ccatcttttt atagtatagg
    79261 tattgacata acaaaggaaa gaaaacagat tgagaaatta cagcatatat cagagaaaga
    79321 tgcattaaca ggaatttata atcgtgctga gactgaaagg cagattaaga aatattttga
    79381 aaaaaattta aatgttatgg gtgcactgtt tatgattgat acagataatt ttaaacagat
    79441 taatgataca gaagggcata tgattggaga tatagtactt actgagatgg catcaggtat
    79501 gaaaaaaata atgcgtgaca gtgatgttgt tggaagaata ggtggagatg agtttacaat
    79561 ttttatgaag aatatttcct cagttaaaga tgcagaaaag aaagcagaag aactattgta
    79621 tatgttccgt catctatttc agaaagaaaa aagttttcta aaagtaactt gtagcatagg
    79681 aatagctata tatccaaagg atggtactac attcaaggaa atatatgcaa gagctgataa
    79741 agcactatat caagcaaaaa atatgggaaa aaataattat gtaatctaca accaagatta
    79801 ttttaaagaa ttagaagaat ttgattgttc ttctcttggt acagttattg attcagaaaa
    79861 acaatatgct gaatgtcctg ataatcttac acgttatata ttccgtatgc tttatcagac
    79921 tgatgatata gaccaggcga ttaatatgat acttgaggtt gttgggaaac agtttgatgt
    79981 aagtcgtgtt tatatttttg aaaatacaga agatggtcga tatacttcta atacttatga
    80041 atggtgtaat gaaggaatct cttctcaaat ggcttatttg caaaacagca attatcaaga
    80101 ctatgaggat tatgaaaagt tttttgagga tgaatcagtt ttttattgtc gagatatcca
    80161 cacattaagt cctaaactag aagaattgtt ttctagtcaa ggtatccact ctacacttca
    80221 atgtgcatat aaagaagata gagttttcag tggatttgtt ggatttgatg aatgcacagg
    80281 actacgtcta tggtcacaag aggaaataag tacattatca ttgatttctc aaattatatc
    80341 aatgttttta caacgtaaaa aaaataataa acttaatcaa cagattcaac aataccagaa
    80401 tattttagat aatattgacc agtgtatttg tgtgattaat aaagaaaata attttttatt
    80461 atatgtaaat aaaaaattta aaaatacata ttctaaattc caaattggac aaccttatta
    80521 tcttgattct atagatattc ataagatatc cattatatgg aataaaaaag aagcatacct
    80581 atgtactagc acgatttaat ggtaaagtaa agtttatatt ggacttaaat taaatttcgt
    80641 tttaaataag atattatttt agttgcttac tgaaaagact agaatctata ttaatgaatt
    80701 atactaattt tataccacta ttaaaatatt gtttgctaaa aataaaaaat agccttaaaa
    80761 cagttgatta taaaaaatta actgctttaa ggctattttt atctttgtga cgaaatagac
    80821 acttgccatt tagaatgtga caatatagta gttgtttaga aaaggcacaa agcattatac
    80881 tttaactaaa gtaaaatgta ttttgctttt agaataaaaa caattaggag ggagctataa
    80941 ttgaaaaaga taatatatgt attatttaca attgaactat taatagtatc tttattaggt
    81001 ctaaatatag ttaaagataa tgaaattaat aatattttat ataacgatac aacaagtata
    81061 tctgtaatgt ttaaagatta taaaaagtta aataaaaatt atagtaagtg gattaaagat
    81121 attgcagatg aaaataatgt ggctatatca aagtatgttt ttaataataa tgaaaaatta
    81181 tctatatata cgactgatac aagtttgaat aacaatataa agttaaaatc aggaaaattt
    81241 cttaatacta attcaaatga atttattagt aatataaaca ctaataatag taatcaagta
    81301 ggtaaattct caactatgag taaagacata tcaattttaa ttagggattt tggtaaaata
    81361 agtgaagttg gagaatcagg aatcttatat atttcaactc aaaatgaaga tacaataaat
    81421 aaaatattaa gagaactaaa tgtagacaga agtatttttg tagcaagatt acatgataga
    81481 tatgttaact caaatttata cttaaatcct tcaataatta gagatttaat actaattatc
    81541 ctttgtttct tggctacaat aatacattat tcaattagtg tgagtagaga ggcttctatt
    81601 ttaagattaa atggatactc taagctagat ataattgcta gagttataaa aaatatactt
    81661 agaattatga ttttatcatc tgtcacagca ttattaatat atataatcta tattttaaaa
    81721 ttaaatatag gtgttagagc atgcttatac tttgctatgt tttcgattat atgtattttg
    81781 ataaatattt tgatatctat attaatagtt ggttttaata gtagaagttc taaatatgtg
    81841 ctatctctaa atggaaaaaa atcttatggt tttgtaaata taatgcattt cacattgaaa
    81901 attgtatttg tatcatttct tatattatcc ataaataact gtattttaaa ttataatatg
    81961 ctacaaactc agttaggaaa tctatctgag tgggataaag caaaaaatgt ttataatctt
    82021 actcttaaag atacaggcga acaatcttta ggaaaggaag aagtaattaa aaatgccaag
    82081 attaaaggtt tctataaaaa tttggtagaa gaaaaagatg ctttcttaat agattcaact
    82141 aattttgaaa aacttgaaga tggaagttac atgtatgaaa taaattcaaa gggtaaaaac
    82201 ccagaagtaa gtcaatatgg taaaaatata aaaataaata aaaactatct taaagttaac
    82261 cctatttact caaatggcaa agaaatattt aatctaatcg attatgacga taagactata
    82321 aatttattag ttcctaaaaa gttacaagta catgaaaatg agattaaaaa agagtttaga
    82381 gaattatttt attttgaaaa aatagaagta gaaaatatgt acaataaaga gttaaataga
    82441 gagttaaata aaacaaagaa gtccgattta aatgttaata taatatatgt agataataat
    82501 caaagctatt ttacttataa ctcccttgtt atggatgaca ataggaatct cattgatgac
    82561 ccaatagcaa tagttgacat agataatatt gatgattctt tttatctttc ttatatatct
    82621 agatgtgtat attttaattc taagaaatta gatgcccttg cagatataag tagcattatt
    82681 gaagctcaag gtgtagaagc gcatatccaa agtttacatg ctgtttataa tgagtatggt
    82741 ttagaaataa ataaactaga aaaatatttg aatagtgaaa tttttactat aataataata
    82801 gcaatatcaa acttaatgat tacctacaat atagtagcta gctactatga aagaaataaa
    82861 tataagttat atattaaaaa aatatttggt tactcaacta cagctagaag tatgttgtta
    82921 atagtctcat taatattaac aaacattatt ccaataggca ttatatcaac aagagtagat
    82981 ttaagtaata atattatctt atttggactt ctaatattag ttatagaagt aattgtatct
    83041 attgtattag acaagattat ctcaaatagt tcatttaata aaattataaa aggagaacat
    83101 taaaaagatg atttcattaa taaatatatc taaaaaattt aaagataaat ctataataga
    83161 caaatttaac ctagaaattt ctaagggcga gtttgtagcg ataacaggaa atagtggttc
    83221 aggtaagaca actttactta atataatggg attattagaa aaacctaatt ctggtgatat
    83281 tataataaat aatataaaaa atccaaatag taaacagata agaattttac aaagggattt
    83341 ttatggctat ctatttcaaa attatgcttt aattgagaat gaaaatgttg aaaataactt
    83401 gaaaattgct ttaaagtatc aaaaaaatat caatcataat gaaaaaataa attacgcact
    83461 tgagtctgta ggtcttagaa aatacaataa aaaaaagata tacgaattga gtggaggaga
    83521 acaacaaagg gtagcattag caagagtaat attaaaagaa tgtgaagtaa tatttgcaga
    83581 tgaacctaca ggtaatttag ataaaaaaaa tagagacata gtatttgata tacttaaaag
    83641 tctaaataag aatggtaaaa ctatcgtatt tgtaactcat gatttagatt tatcggagca
    83701 ggcagataga gttataaaat tgtaataata taaactataa taaatataag aaagagatta
    83761 cagctaaatt aagtttaata ataatacgaa tagaatttaa acattaagta aattagtagt
    83821 ttgtaaatat aagtataata tgatatcata aaggctcaaa agaaatttta tataataaga
    83881 aatctaaaaa taacaaatgg aggacatata aagatggaaa atttaccaaa ttgcccgaaa
    83941 tgtaattcag aatatactta tgaagatgga actcttttag tttgtccaga atgctctcat
    84001 gagtgggcat taggattggg agatgaagaa gattcaaata ttatcaaaga tgtaaatgga
    84061 aatgtattaa atgatggaga ttctgttaca gtaattagag accttaaagt aaaaggaagt
    84121 tcatcatcta taaagattgg aacaaaagtg aaaaatatcc gtttaatcca tgactcatca
    84181 gatggacatg atatagaatg taagatagat ggttttggag ctatgaagct aaagtcttct
    84241 gttgttaaaa aagcttaata ttataaataa gctgtagtgt ttattgtttt tcagtacagt
    84301 ataaaaccat aagaatctat taagtaataa aagtttgttt atttatcttt atattttctt
    84361 atggttttat taaatataaa ttttattgaa caccaaaata ttctctcctc tacaaataag
    84421 ccaatcttat ttaaactaat atactttgta ctatttatac tgaaattgta aatttaaatg
    84481 ctatgttatt taggtttgta tagttaattt atatatttct gattttataa attgtattta
    84541 ttattatatc ttgattctaa aatcattaaa aatttcaact tctataaaga tttacaattt
    84601 atcaaataca ttatgagtat ataaacaatt tattattaca gtgctacatt taaaataagt
    84661 cttagtataa aggtattgtt acaagtataa ataaacttat gtatgctatt ggaataaata
    84721 ataccttaaa ttataattaa gaataagaac tgttaaataa gggacttgat tatcatttag
    84781 ttatagataa tataatatta aaaataaagc ttaagaggag aaaaaatatg atagatatac
    84841 ataaaaatat atatgataat aagttatttg aggagctaaa gattgattgt aagaagtgtt
    84901 ttggactttg ttgtgtagct ctttattttt ctgcttcaga tggatttcct atcgataagg
    84961 aatcaggaaa accctgtatt aatttacaac cagattttaa atgttctgta cataatagtc
    85021 ttatgaagcg aggttttaaa gggtgtactg catatgattg ttttggttca ggtcaaaaag
    85081 tagcacaagt aacatataag ggaatagact ggatgcaatc atcagaacta acaaatcaaa
    85141 tgtctgaagt gtttttaatt atgagacaat tacatgaaat gttatggtat cttaaagaag
    85201 catctgtatt aaatatatca gatacaatca aatcaaaaat tgatttaata attgaagaaa
    85261 ctgaaaagat aactaatatg ggaccagaac agataattaa tttggatatc atatcacata
    85321 gaacaaaggt taatttatta ttatcacaag cgagtgagtc tgtgatggga aaggttaaat
    85381 catttatcaa gacttctact cttaaaaaca tgaaaaaatt aagtaaaaat atagatttaa
    85441 taggagcaga ccttagaaaa ataaatctaa taggagcaga tttaagaggt agatttctaa
    85501 tagcagcaaa tttaagaaat acagatttga gtggggcaaa tttaatagga gcagacttaa
    85561 gagattgtga tattagaggt gctaatcttg aaaatagtat atttttaaca caattacaag
    85621 taaatactgc aaaaggagat tctagtacga agttaccagc ttcactaata cgccctaaat
    85681 actgggaaaa ataattaaat taatacataa ttttacaaaa tatgaacttt tttgacttta
    85741 attcatatta tacattagag attctttaca agaatttctt aatataatat agggagagat
    85801 ataaaaatga gttatcaaaa ttataaatgt gaaagagatt atgtgtatga tgattataaa
    85861 tacaataagt gcaacaagtg ctataatgat tatgaggaaa tgacacatgt tcatgaatat
    85921 tcagaaagtg ttaagttagc agaagaatgt gaggatagac ataaccaccg tgcagcaggg
    85981 gttactggtg aagctatacc aataaatgga ggtacaaatc atgttcataa aataaatgat
    86041 aatgtagatt tccttgacca tttccataag atatgtgtta caacagggcc agcaattaga
    86101 atacctggaa ctgataaaca cattcactta atatgtggag aaactactgt taatgatggt
    86161 cattgtcata aattcctttt tactactcaa atagaagcac ctttagtata agctgatgtg
    86221 aattattgta gtgaatttgc tagattatag tataatatat aatagataat atttaaactt
    86281 aattaggact atgatattta accttcgtag tcctttctaa gttttgtata aaaaagtgtt
    86341 atgcaattaa aagtgatata gggaggaaat ttttatgaaa tctggaataa ttcttgaaat
    86401 gaaacaaata aattcaacag aatatgacga aatgttgcaa gtctgggaat catcagtaag
    86461 agcaacgcat gattttttaa cagaaaaaga tattgaatct ttgataccat tagttgaaat
    86521 tggacttaaa gaagtagaaa atatagtttg tataaaagat aatgatataa taaagggctt
    86581 tataggaata gataaagata aaattgagat gctctttata gaagataaat atagaggaaa
    86641 tggtattggt aaaaaattaa taaaatatgc tatagataaa tacaatgtaa aatatgttga
    86701 tgtaaatgag cagaataaaa aagctgtagg attttatatt cacttaggat ttaaagtgtt
    86761 tgataggtct gaaatagatg gacaaggtaa cccatttcca atactacata tgaaattaat
    86821 ttaaagttat acttctcatt tattcgcaaa aatatttact taaattttta tacaaataaa
    86881 agtcgtgaca gtcttaggac acgacttttt tactacacta ttaaattgaa atttatctgt
    86941 tctatattat gattattaga tgtagttttt ttattttaac tatgtactta aataccaagt
    87001 atacccatac ctatcaagta cttcagtagc gccatcattt tgatgtggtg gtgggtgtgg
    87061 taaaaattct tgtacaagtg taccaccttc ggcaagtttt acagatattt cttctatcgc
    87121 ttctcgagat ggtagaacaa cacaaatcgc catgccagaa attacaacag gcttgtctgt
    87181 atccgcaccc attatacaac cttcgtattt tgtgaaagta acacttgcgt gcataatagg
    87241 attgtttgga ttgctgtcta atcgcgcaaa tatagttttt cctcctccga aagcctcagc
    87301 ataaaaatta aatgcttttt cacaagtacc attaaatatt aaatatggag ttagcatgac
    87361 caatatatcc tccttgatat agaataattt atagttgcac ctgataatct aaattatgat
    87421 ttagtaaatt gtatcatagg gaaaccttga agtatataat tttttattat tatattatac
    87481 aaatttatta atttaaaaaa atgttatatg tacggaaggt ttacaggata aaatataata
    87541 aaaagattaa ggtgacatta taaaaaatgt atattgacat tgacgctacg taattgtata
    87601 tactttgtct taaaggagat ggtaaatatg aatattatag aaattcgctc agataaaata
    87661 tacaagaaga taatggatgc accaataaac aaaaaagaag atatatacag atatgaatta
    87721 atgaagcctt ttgaatttaa gtggaagtgt atgaatgttc caatagttgc tagacagaaa
    87781 ggtggatatg atgtaattat agcaagtgaa atgttagggg ttttatcgcc taaggatatt
    87841 gatgaaaagc aaaaaaagaa tataaatgtg ttatctgctg ataaaatttg gggcacttgc
    87901 aaagaaacca tagaaaactc tataaatgct tttataaaag aagggtatga tttaaacatt
    87961 aaggactata aatattcaat attattggcg aatccaaata gtccttatac aatattaagt
    88021 gatggatact ggggtgatgg tgggattcct ggatatatat ttctatcatt ggttcctaat
    88081 gaatatacta tcaatagatt accagtatta atagcacatg aatgtaatca caatattaga
    88141 tttcagttta tagagtggaa taataatata acattagaag aaatgatgat aaatgaaggt
    88201 cttgcagaaa attttgcaac atggatgttt ggagaggaaa tgttaggacc ttgggtcagt
    88261 agaacagata tcgaaacatt aaatacttat ataaagccaa taataaaaag tgctttaaaa
    88321 taaactggat ttcaaaatat aacatcttat ctttatggtg atgatatagc taaaatgcaa
    88381 ggatattttc cagtagggtt gccttattgt gcaggatatg cttgtggata ttatatgatt
    88441 aagtattatt tagaaaagac aaataaatca ataatcgaag cgactttatt gccttatagt
    88501 gagataatcg aaacagtaaa agagttttgg gaataaattt tataaaatgc ataatttgaa
    88561 ataaattatg caattatttt atttttaaga aaaaataaat tgacaataat ttataagaaa
    88621 tatacaataa tatatataaa gaaatatttc aatatttaaa agttttaaga tttcatatct
    88681 agagtagcta acattacatg ttagtttctt gttacttatc taattacttt atatttcgta
    88741 gttatatata aaattactat aaaaaatgaa atatattaaa caatcaactg aaaaatgaaa
    88801 tgttaataaa aaaaaattca aattataaat attaaatgaa tataattaaa acaaatatat
    88861 aaatttaagt ataacactca cattttaatg tattgtgaaa tttttgttga actttatgta
    88921 ccataactta taaaatttat gtcatgttat atttgaataa gtaataaaat tgtagatgta
    88981 aattaatcta caaaatttat atgaaatgga gttgatgcta tgacagaatt aatgattata
    89041 agtgggttag tactattgat ttgtataact tctagcaagg tattgtataa atttggagta
    89101 ccaatattat tgatttttat cttactaggg atgttatttg ggtctgatgg gatggtagga
    89161 atctattttg ataactatga actaacaaaa caattatgtt ctattggact aatatttata
    89221 atgttttttg gagggtttgg aacaaactgg aatatggcta aacctgttgc tataccttct
    89281 atattaatgt cttcactggg tgtaataatt acggctgggg ttacaggtat gttttgccac
    89341 atggtaatag gaactagttt acttgaaggt ttattaattg gggcaattgc agcttcaaca
    89401 gatgctgcat ctgtgtttgc tgtgttgcgt tctcaaaaac taaacttaaa gggttcactt
    89461 gcatcattat tagaagttga aagtggaagt aatgacccaa tagcgtatat gttgacacta
    89521 attcttttga cattgatgaa taattctggg gtagaactta ttgcaccaat ggtaataaaa
    89581 caaatagctt ttgggttagc tataggattt atactagcaa aattatctgt ttatatttta
    89641 agacattcaa acttcgagat agaaggattt tatactatat ttataacagc tattgcaata
    89701 ctttcttatg catttagcga gtatcttgga ggaaatggat atttaagtgt ttacatttca
    89761 ggtattatta taggaaatag taggatacct cttaaaaaaa gtttggttca tttctttgat
    89821 ggaatttcat ggattatgca aataatgtta ttctttatgt taggattgtt atctttccct
    89881 tctaagttac caaatgtatt tggtatagca atggccatat ctatattcat gatagttatt
    89941 gcaagaccat tagcaacatt tatagttcta gcaaaattta aattctcaaa taaagaaaaa
    90001 ttattcatat cgtgggtagg tcttagaggt gcggcttcag tagtttttgc aatttatgct
    90061 gttactcaag gagtagccat agagaatgac atattccata taatattttt tatagcgttg
    90121 ctttcagtag gaatacaagg ttcattgata ccaactgtag ccagaaagtt ggatttagtt
    90181 gatgataata cacctgtatt aaaaacattt aatgattatg atggagaaat tagctctaaa
    90241 cttatcgaag taaatgttga tgagggtaat aaatgggcta ataagagtat aatagattct
    90301 aatataccag acgatatatt aatagttatg ataaaaagaa aggaacaggt tttaatacct
    90361 aaaggttcaa ccattataaa aacaggggat attttggtat tgagtggaga tagaattgaa
    90421 gaattaatac aattataatt tattttgtat tgactttaac ctaaggggaa agtttaaact
    90481 taaattaatc aaatctaatg cgcaggtgat gagatgtttt ctataggaat gttttctaaa
    90541 ataaataaaa taactacaaa gacattaagg tattatgaag atatagggtt gttaaaacca
    90601 gaatatgtag atgaatttac aaaatatagg tattatacaa cagagcaatt acctaaatta
    90661 catcagataa taactttaaa acaaatgggt ttatcattag ctgagataaa aaaagctgta
    90721 gaaaatcctg aagaagttga aaatatttta atgaataaag aaaaagaaat gttggatgta
    90781 attaaaagtg aagaatataa aataattaaa ctacgtaatt accttatgaa tttgaaagga
    90841 gaagtcaata tgaatgatgt aattattaag tctttaccaa aagttaaagt tgcttctatg
    90901 agaaaagtgt taaaggggta tgatgaactt tttaatctat ttccaaatgt aatggctgaa
    90961 gaaatgatga aaacagggtg tacatgtgca gttcctgatt attgttttaa tatatatcat
    91021 gatggtgaat atagagagac tgatatggat gttgaaatgt gtcaagctat aaatgattta
    91081 aaggaagata cggatatatt aaaatttaaa gaattagatg cagttgaaaa tgcagtttgt
    91141 atattacaca atggtccata ttcaacatta ggaaaaactt acgcagatgc atttaaatgg
    91201 atagaggaca ataaatataa agtggttgga aatcctagag aatcttatat agatggtata
    91261 tggaataaag agagtgaaga agactggttg acagaagttc agataccagt gaaacgcatg
    91321 ttataatatg tctacaaagt ataaataaga ataaaaaagg tggtgtctca aagtaaactt
    91381 tttagtttat gagacactct tttttatatg aaatcaagta tatttttata attacgatta
    91441 tgaaaaaagg cttatctcta tttttagaca gcctcttatt tttttattat aatagttttc
    91501 taaagatgct ctatttataa atttttatta aagactttat aaataattgt atttaatata
    91561 caaaatatat ataaatattg atgttttata tataaagttg tatatttttt taaggatata
    91621 aagtaaaaaa atatacaata tcaagaaaaa aagatattgg gtatttaaag taatacttta
    91681 tttaatttta agtaaatcgg gtatctacat atatagatac taatttcaaa gaataggagg
    91741 gtgtttatat ggaaatattc gcaataggac attcaaatta tccatatgat aagcttatta
    91801 atatgataaa aaaatatgac ataaattgtg tagttgacat tagagaaact ccatattcta
    91861 aatataatat tcaatacaat aaagaggcat ttaacgaatc tcttagaaat tccggatttt
    91921 tatatatata catgggaaaa gaatttggag ccaaaagaac taataaagat gtatatacgc
    91981 aagaaggtta tgcagatttt gagaaagtag caaaagaaga tattttttta aacggaatag
    92041 aaagattaaa aaagggttgt caaatgggtt ataggatagt tttattagga gctatgcaag
    92101 aacctataag atgtcataga agtatcttgg tgggaaaagt attaaataaa gaaggttttg
    92161 atgtaaaata tataatgcat gaaggaaatt tggcatatca ggaagatata gaggaatcat
    92221 tattggataa gtattttagt gatagaaagc aactgagtat tgacaattta ttagggagtg
    92281 cattaacgag agaagaaatg atacaagaag gttataagct agctaataaa gaaataggat
    92341 atagaactga gaaactaggt aaataaaaat atacaagtag ataaaataca gtacttatct
    92401 taagtaaaat aatattatga atttataata gctaggcatg atgtgccaat taaaaatatt
    92461 ctagttattt aataatatca ttaaatttag ggtatttttt aatagcacat catgttgcag
    92521 ttttaaaaaa taaaatctct aatattgcca taatcaactg ttctattaag agtaggatga
    92581 ctagatataa atctaactgt aatttttgaa tttaacaaac aaggatttga aattaaaaat
    92641 actctatctc cattgacaat agaagtaata gctactggca aaatatctac aaatgtatca
    92701 tatctgtttt tagcaatttg ataaggataa tttcctacaa aaacaaatag atttaaatca
    92761 tatatattat cagtaaacca agcccattga ccataaactt tgtcgatatt cattgtgcct
    92821 aaaccaagtg tatcaaagta tgttgctata gttaaataaa tattttccat gttttctaaa
    92881 tatgaaacag tatatcttct gaaacgtatg ggtgctgtgg aagaaatagg ataaaccata
    92941 tttacattta gattatttgc atttaaatta accaaagtat cacatcctaa aattagtcta
    93001 taaaatacaa tatttaaatg gatgcgattt tgttacatct aaagtgtaat attttatata
    93061 ttgaaaaagt ggtaaaagtt tggatgatta aataatatta taaaaaatat ataaaatgta
    93121 cttattgtta ttgctacacg atagtgatac aatattaacg aaatatagct acttttaata
    93181 ataacggaaa atatttatat taaattaata aatattttaa atgtggtatc cataaaaaat
    93241 aataaacata agataattat aaagatatac tgtgttcaaa tgatattaaa caagatttat
    93301 attatttgaa agcagtatat tataatgcga acaatacaat tctaaacttt gcattgtcaa
    93361 tttacagttc gataaactaa ttaaaaatta aatttatata aagagggaaa agaggaatag
    93421 ggatgtttat aaggaaaaat gttataaagt tagcaattcc tataatgata gagcagacgt
    93481 ttgtcatgct tttaggagta tttaatacaa tgatggcagg tcatattggg gaagaagctg
    93541 tatctgcagt tggaatggtt gattcaataa acaatatatt tatatctgta tttgctgcac
    93601 tatctgttgg agctactgtt gttgtagctc aacaaatagg aaaaaaagat agtgaaaagg
    93661 tgaatgaaac tattaagcag gctctagtgt ctggagtaat attatccttt acaataacaa
    93721 tattgatgtg ggtttttaga actggtgtaa ttaatttatt ttatggttcc gcagaagaat
    93781 tggtaaaatc aaatgcaaaa ttatacatag agtttacatt atttacgtat ccatttattg
    93841 cgacacaaca aatagcaaat ggtattttaa gagggtgtgg agatgtaaag aaacctatgt
    93901 atgtgactat gtttatgaat atagtaaatg taacattagg atatatactt atatatggta
    93961 ttgatttaaa tcctctagga ataaatttgc aaacaccatc ctatggcata acaggtgcag
    94021 ctatatctat tgctatagct agaataattg gatgtatagt aattataaga gctttattta
    94081 aaggaaacga atttatatct atgggtaaaa tatttccatt taagattgat gttgaaactc
    94141 aaaagtctat atttaatata ggaataccag ctggagttga acaactactt tttaatgcag
    94201 gtaaattgat tgttcaagta tttatagtta ctatgggaac atcagcaatt gcatccaatg
    94261 caataggaat gtcaattgca tccataataa atgtaattgg gaatgcttta gctttgtctg
    94321 ctacaacctt ggtgggacag tatataggac gtggagatat taaaggagct aagagtactt
    94381 tattatattt aactaaattt gcaacaattt gtttatttat agtaggagct atatttatac
    94441 caattgcacc ctggatttca agtatgtata ctcaaaatgc tagtgtaatt gacatctcaa
    94501 cacaattaat tcgaagtgat tgtttagcta tggtaatatg gcctatatcc tttgtattat
    94561 cagcagggct aaagggagcc ggtgatacta gatatacaat gatgactgca gtaataggta
    94621 tgtggatttt tagaattttt acaggttacg tattgggggt tgtattagaa tttggagtgt
    94681 taggaatttg gataggtatg tatactgatt ggcttgttag agggacttta tattgtttaa
    94741 gattaagagg aacaaagtgg ctaaaacaca aagttgcata gaatatatga aatcactttt
    94801 agatggataa ctctatttag aagtgatttt ttatgtagtt attatcataa ttataagtat
    94861 gatatataag gtgattaaat tacataaata aaggctataa tagtatggat attataaatt
    94921 atatattgag cagaattaca taatttggcg ataaatatta gaaatatata tctatagaaa
    94981 ataatatata tgggtatatt attaaatata aaaaatatta ggtatttatt taataataaa
    95041 ggtgggtatt gttatgataa ataaaatagg aaaaataact ctctatgtaa ataatcaaga
    95101 ggatgcaaag ttattttgga cagaaaaatt gaactttgta gtaacttatg aaaaggaaat
    95161 gggtccaaat atgaaatggg tggaagtagc accaagtaaa aatgaattta caacatttgt
    95221 gttgtatgat aaaaatctaa tgatgaagca aaacaaagag ataaatgtat ctcatccatc
    95281 aataatttta agtacaagag atattaatgg aacttatgaa caaatggcaa ataacgaggt
    95341 tgaggttggg gaattaatgg agatgccata tggaaggatg ttttctttta aagaccaaga
    95401 tggaaatgat tatttggtca gagaggataa ataattttac aaagtattaa atttactcaa
    95461 tatctgatat aattagagac aataattatt ataaactagt ctaggattag aattatataa
    95521 ttaaaaatta agtgtaaatt ttgagtagag gtgataaaat gtttaagaaa atggcagtac
    95581 taaaagatat agcaactaaa ataggtcgta aaaaagcgta tgaactatta gaaatggttg
    95641 aaggtaatga tgcctttgta gctgaggtaa agataaaaaa gaatggaata gaatctaaaa
    95701 aagaagaaat tatgttaaaa gataatcaaa aaataatatt agagtatata gaaggttaaa
    95761 ttttaaatac atataagttg atatactaaa tttctgagat gagtttacat aaaactcatc
    95821 ttttttactt ttcaataact ttgttttatt atttaatata cattttatct ccttagagtt
    95881 gctgatatat aaaaattact gatataataa aagaatggat attaatgtaa tattttatag
    95941 aaaagagggg tattatgctt gaaataaaaa atctttcctt taatgttgag tctaacaatg
    96001 aggaactagg aataataaat gatgttagcc tttcatttga gaggggaaaa cttattgtta
    96061 tcacaggtcc aaatggtgga ggaaaatcta caattgctaa gcttattatg ggaattgaaa
    96121 aagctacgag tggtcagata attttagatg gagaagatat aacaaatctt agtattacag
    96181 aaagagcaaa aaaaggaata ggatacgcat ttcaacaacc accaagaata aaaggtatga
    96241 cagttgaaaa tttacttaca cttgctcatg gaaaaccatt gtctactgat gtatgttgcc
    96301 aataccttac agatgttgga ttgtgttcaa aagactattt aaatcgtgaa gttgataact
    96361 ctctttctgg aggggaaatg aaaagaattg agatagcaac tctttttgct agagatttaa
    96421 aggtttctat atttgatgaa cctgaagcag ggatagacct ttggagcttt ggaaaactca
    96481 atgaaagttt taagaaaata catgaagagt ctaatcagac tataatcata atttctcacc
    96541 aagaaagaat attagagtta gctgatgaaa taattgttct acaagatggt tcagtaaaaa
    96601 gccatggaac aaaagaggct atattacctg aaatcatgtg tcaagttaat tcaagttgtg
    96661 aattaatgaa agacatgaat taattagaaa ggaaggcaaa ttaaatgaac aaaatagatt
    96721 taaatctttt agaaaaagtt gctgaacttc gtggaactcc attaggagca tacaatatac
    96781 gtaaaaatgg gcaaggagta gagagacatt caactgaaaa tgtaactata attcctaaaa
    96841 ctgataaacc tggaatagat attatagtaa agccaaatac aaaaggagaa aatgtacata
    96901 taccagtaat agtaacagag gctggtgtac aggatatggt atataatgat tttgaaattg
    96961 gagaaaatgc agatgttgtt ataattgctg ggtgtggtat acataactgt ggttgtgatg
    97021 atagtgaaca taatggtata catagatttt tcttacgtaa aggagctcgc ctaaaatatg
    97081 tagaaaaaca ttatggtgaa ggtgatggag aaggaaagag aattttaaat ccagttacta
    97141 ttgtcaatat ggatgaggat tcatattgtg aaatggaaac aattcaaatt aagggtgtag
    97201 attcaactaa aagagaaatg gatgcaaacc taggtaaagg agctaaaata gttgtatttg
    97261 agaaattatt aactcatggt aatcaagttg cagaatctaa tatgaaggtt atcttagagg
    97321 gtgaaaactc ttctgctcaa gtagtttctc gtacagttgg gcaagataat tctaagcaaa
    97381 agtttaatcc ttgtgttatt ggggattccc tttgttctgc acatgttcaa tgtgattcaa
    97441 taattatggg aaattctcaa attagtgcta tacctgaaat tgctgcaaat catccagatg
    97501 ctcttttagt acatgaagca gctattggaa agattgcagg agaccaaata ctaaagatga
    97561 tgacattagg tcttactgaa gaagaagccg agcaacaaat acttaattgc ttcttaaagt
    97621 aaattaaaga ttttatttaa tttaatataa ttaatatagt ataatatagt gaataagtct
    97681 aaaatatttt tatttttagg cttattttct ttatgtaaga aaagctatta gagaaattat
    97741 attgtaatta ggatgtggaa taaatgaaaa atttacttat aagaaatggg acaataatat
    97801 ctccaacaga tggtatcaaa tttgaaaaaa gagatatctt ggttttacat gggaaaatat
    97861 atgctattgg attgaacctt aaagagaaaa taagaaaaga aaaattactt acaaataaag
    97921 agttcgagat aataaatgcc gataatatgt atatttcccc aggatttata gatgttcaca
    97981 cccattgtta taagagaaaa ttacctacag gtatggattc tgattcaatt ggaattgaaa
    98041 aaggttctac agttatattt gatgcaggta cagctggtcc ttcaaactac tatgatttta
    98101 aaaaaaagta tatggatgag tgtaaaacag aagtatattc ttttttaaat gttacaaatg
    98161 agggactaaa tatattgaat gaatcaactt ctttagatgt tataaatttt gacaaggttg
    98221 agtcaattgt agaaaaaaat atagaaaaga taaagggtat aaaagtaaaa gcgagtaaat
    98281 ttcaatctaa tgaaagtggt atagatataa ttaagaaatc aaagcaagtt gctaaaaaat
    98341 taaatttacc cttagtggta tatataggag agtatccatc atatatagat gaagtaatga
    98401 atattttggg aaaaggagat gtggttacac cggtatatgg aaatagtaca aatggaatcc
    98461 ttaaagaatc tggcacatta agaaaatcag taataaatgc aaagaataga ggagtattgt
    98521 ttgatgtatg tcatggagtg gaccaatttg attttaaagt ttttaaaaaa gcaataaagc
    98581 aaggtttaga gcctgaccta ataagtactg atatgcatat aaaaaacatg aaagacataa
    98641 actattctct tttaaatgtt ataaataaaa ttatggaact tgggatatcc ctagaaaagt
    98701 gtatagaaaa agtaactgaa tacccaacaa agattttcga tttacatgga aataaaggca
    98761 gaataaagat tggtggagaa ggtgatttta caatatttac aatggaggag tgtaatgata
    98821 ttataaaaga ctacaataat aatgaacttg ttttaaataa aaaattaaga ttgcaatata
    98881 ctgtaaaatc atggatgaaa agcagtgaag tttatagaca tggatacgaa aatactataa
    98941 taaactaaac aatagtgata aaataataaa tatatgttta aattggtata tattggataa
    99001 atatctaagg aaacaacaat taaaaaataa taattttagg ggaggtattt tagtatgaaa
    99061 gcatttgttg ataaggatgt atgtgtagct tgtggagcat gtataggaac atgtccagac
    99121 gtttttagta tgagcgatga agggcattca gtagcaattg aaggagaaat accagcagat
    99181 ttacaagatt tatgtaaaga agccgaagaa ggatgtccag tttcagctat aacagttaaa
    99241 tagagctgtt taaatttatt tttaaaataa atatataaga tttaattggt acttaagcta
    99301 tagtattaga aatttctatt actatagctt tttaaaatag ataaacttaa tatataagat
    99361 attacttttt acaaatatgg aggactgaaa tatgaaaaaa aattatgaaa tagtattatt
    99421 cgatttagat ggaacactta cagaccctaa agaaggaata acaaagtcta ttcagtattc
    99481 tttaaatagc tttggcataa aagaagattt ggaaaactta gaccaattta taggaccacc
    99541 attacatgat actttcaagg agtattataa atttgaagat aaaaaagcta aagaagctgt
    99601 tgaaaagtat agagaatatt ttgctgataa agggatattt gaaaataaaa tttatgagaa
    99661 tatgaaagag atattagaaa tgctctataa aaatggtaaa atattattag tagcaacttc
    99721 taagccaaca gtttttgcag aaactatact tagatatttt gatatagata gatattttaa
    99781 atatatagca ggtagcaatc ttgatggtac aagagtgaat aaaaatgaag ttatacaata
    99841 tgtactagac ctatgtaatg taaaagataa agataaagat aaagttatta tggttggaga
    99901 tagaaagtat gacataattg gagctaaaaa aataggtata gattctattg gagtattgta
    99961 tgggtatggt tcttttgaag agattagtga aagtgaacct acttatattg tcgaaaatgt
   100021 agagtctata aaagatattt tgttataaat atcttttata gacaaaaata ttacaaaatg
   100081 gtgtcgcata tttaaaaata tgatattata gttaaggaag tcatttaaaa aagaggagga
   100141 tgcacttaaa atgaaatcta ttttaattat gggtggaagc gacttcatag gttctgcact
   100201 tgctaagcgc ttgattaaat gtgggtatca aattgatata cttacaaatg gtaaaaagga
   100261 aatagattat aatggtttta aagaacatct aatttgtgat agaaaagttc gaaaagatat
   100321 ggaaaacatt atcacaggaa gaaaatatga ttacatatat gatatgacag catatacaaa
   100381 agaagatgta agtaatctga ttgattttat aagcatggat aacttaaaaa agtatatagt
   100441 attgtcagca ggagcagtat ataaagatag tggaagaaat ataaaagaag aaaatgagaa
   100501 aggtgaaaat gaaaactggg gaaaatatgg gttaaataaa aaagaggctg aagattttat
   100561 tataaatagc cctataccat atataattat tagaccaact tacatatatg gtgaaaataa
   100621 taatttatat agagagtatt atttctttga aaaaatagaa aaaaatgaaa agataccagt
   100681 accaaaagga aaacaagtta gtaatcaatt tatatatatt ggggatttgg taaaggtatt
   100741 ggaaagcata atgaaaaatc ctcatgtaag agaggcctat aatgtgacaa atccacagtt
   100801 aatttcttgg gatgacctta tatatacatg tggagaaatt attggcaaag aacctataat
   100861 aaaatatgta gatatggaaa aagtagagtt tagagaaaga acgtatttcc catttagaaa
   100921 tatagacttt aatcttgata taaataagct tattgaacat gggctttata taccaaacgt
   100981 gttactaaaa gaaggtctta cagcaacata taaatggttt tcagcaaata agccaaaaat
   101041 gcatgacaga aaaatgaaca aagttgagtc tgtaatgcaa atagtttaaa aaaataaata
   101101 agtaggtaga tattttgaac tcaaaaatta agtatttttt aaaatttttt atcttaatat
   101161 ttattttgat ttttatatac tcagttgcga tagagccgag tctattaatt gtgaaaaaat
   101221 ataatataag taaaaatgga gcattgataa aaaatgatac aattgagagt aaatctgaaa
   101281 gtgtaaaagt agttcaaatt tcagatactc aaataggtag tttttattca actaagaatc
   101341 tcaaaaaagt agctaataag attaacactt tgaatccaga tataatagta tttactggtg
   101401 atttaattga ttactctaat aaaagtccaa gtgtagatga aattacaact attttatcaa
   101461 gtatgaatgc taggttggga aaattttcag tatttggcaa tcatgattat atgtataaac
   101521 ttcctaggta ttataggcag attatgaaaa attccaactt caatctttta gtaaatgaaa
   101581 ataaaaaaat aaaattaaaa gatgataaat atattaatat attaggtgtt gatgaaatat
   101641 taaatggaaa tcctaatata aaatatctgg agagtcaaat agataataaa agttttaatt
   101701 tattgttagc acatgaacca gatttagtag atatgcttag taaagataca atgaatttag
   101761 ttctatctgg gcatagtcat ggtggtcaaa taagattacc tattaaggga gcattagtta
   101821 ctcctccata tggaaggaaa tatactaaag ggttttatga tataaatgga aatcatttat
   101881 atgtgagttc gggtcttgga agtacaaaat taccatttag attttttaat ataccagaga
   101941 taatagaatt taatattata atctaacata aaatatttag aaaatata
//
LOCUS       DAEORM030000008       100101 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.008, whole genome shotgun sequence.
ACCESSION   DAEORM030000008 DAEORM030000000
VERSION     DAEORM030000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 100101)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 100101)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 100101)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..100101
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.008"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            complement(192..1595)
                     /locus_tag="KRH23_000825"
     CDS             complement(192..1595)
                     /locus_tag="KRH23_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA];
                     GO_function: GO:0042910 - xenobiotic transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006855 - xenobiotic transmembrane
                     transport [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HHS5224116.1"
                     /translation="MEEKYKEPLEYEKVSKLLTKYAIPSIIAMLVSALYNIVDQIFIG
                     QGVGVLGNAATNVTFPLTTICTAIALLLGIGGASKCSLELGAKNSEKATKAAGNSICL
                     MAVFGISLFIVVSIFLTPLLKFFGSTSEILPYAHTYTKITSIGLPFLIMSTGMSKLIL
                     ADGRPKASMFCMLIGAVINTILNPLFIFVFNMGIAGSALATVIGQLISFGISVHYIKN
                     FQHIKLHKKSFKLDSIIYKHIFALGSSSCFNQLAMTVTQIVMNNTLAYYGARSVYGSE
                     IPLACVGIIIKVNMIFISIIIGISQGMQPIIGYNYGAEKYNRVKEAYKFAVGSATIIS
                     VIAFLCFQLFPRQITSIFGNGNETYFIFAEHYFRTFLFLTFINGVQIVSSTFFTSIGK
                     SVLGLFTSLTRQILFLIPLIVILPMFMGIDGVMFAGPIADAAAAMVCIYFAVHEMKSL
                     TIKQNNLMSNHNKIAEV"
     gene            complement(1579..2106)
                     /locus_tag="KRH23_000826"
     CDS             complement(1579..2106)
                     /locus_tag="KRH23_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HHS5224117.1"
                     /translation="MHEQIDYCERKKIRTINIKGENMRELLKWVSIINRYNTNYIDRK
                     LADIGINNSQYFYVLHICNNPGITQDTIFEKILVNPSNITRALANLEKEGFITREPGV
                     KDKRTWHLYPTEKSLECYDEILKITNGYVEELLSSFEKEEQELFMSMLKKVAFLAIDM
                     NEEAKLEAKENGRKI"
     gene            2386..2901
                     /locus_tag="KRH23_000827"
     CDS             2386..2901
                     /locus_tag="KRH23_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HHS5224118.1"
                     /translation="MLEYIILGFLMEKELSGYDLKQIMSESTSYFFDASFGSIYPALK
                     RLETKGYIHYHEVIDGSKLKKLYSITNTGKEVFLEWLKKPINFSKTKQDHLVNIFFYK
                     YLPKEIIETNLKMLITEVELLLNKLSKQKNDAEENHCVDQYTYMYATMIYGVDYYNFV
                     INWCKDLLKNL"
     gene            2950..3453
                     /locus_tag="KRH23_000828"
     CDS             2950..3453
                     /locus_tag="KRH23_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HHS5224119.1"
                     /translation="MRLLIHDLTDKELEKLLPKLDDNIKILPNTKEIHKCIGCFGCWI
                     KTPSECVVKDYYSNMGKLINDSDGIIIISRCCYGGFSPFVKNVLDKSINYILPYFVIK
                     DNMMRHKSRYDKQINLKAIFYGDCITEAEKETATKLVNGNAINFNIKEHSVCFYENIQ
                     DIRGESI"
     gene            3450..4100
                     /locus_tag="KRH23_000829"
     CDS             3450..4100
                     /locus_tag="KRH23_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224120.1"
                     /translation="MNIVMINGSPKVNKNNSQYFLSELKQLIQNDNKVFTFKVDSTSK
                     YPDALNAILNCDRLIIASPLYVDGIPSHLLHFLEKCEKFLKTQNKKPIPVYAIVNCGF
                     NEGEHNHLAIQMIEHWCKKINFTWVQGIGIGAGEMFGSLESVPLGKGPKKDLGIALKE
                     LSKNILSDNIHIDDSNKSTIFISPNFPRFLYKLMGNHQWNTQAKSNGLTKSDILKK"
     gene            complement(4235..5014)
                     /locus_tag="KRH23_000830"
     CDS             complement(4235..5014)
                     /locus_tag="KRH23_000830"
                     /EC_number="2.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase"
                     /protein_id="HHS5224121.1"
                     /translation="MNDTVKEKLAESLTSDTTDILPYLPYLLQDFWELGSSPEQMLQL
                     FRKHIPFNEDTKVLDLACGKGAVSVKLAKELNIHIKGIDLIPEFIDYARRKAIEYKVD
                     ALCNFEMNDANSSVKIEHDYDCVIFGAVGDILGNYKETISKLLPTIKSKGFILIDDAY
                     VVDKSTNEQLNFERVYPTYNEWCILFKELGLKLIECIPCLELENDVDEEMNWIITRAN
                     ELIKKYPSQKDIFEQYVISQKNEYTDLQQDLVGATWILQKE"
     gene            complement(5126..5377)
                     /locus_tag="KRH23_000831"
     CDS             complement(5126..5377)
                     /locus_tag="KRH23_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3781 domain-containing protein"
                     /protein_id="HHS5224122.1"
                     /translation="MNVENELLKNLDRLHTTELGVVRIKKNLSLETNDVVNWCKTKIE
                     SPNAIINRKGKNWYISVYDCIITVNAHSYTIITAHKEKK"
     gene            complement(5571..6440)
                     /locus_tag="KRH23_000832"
     CDS             complement(5571..6440)
                     /locus_tag="KRH23_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHS5224123.1"
                     /translation="MDNNLITIEKTLDYIEKHLLDEMLDLNVISKEIGYSKYHLHRMF
                     TSVVGFSVHNYIQRRRLTEAARMLIFTEKPIIEIALISGYDTQRSFSRGFKKMFKRSP
                     NFFRRHQDFLPLQLKFDIHNRKKLRGDMVLDVKKVNCADINIVGYSGKVRKGFHIIGK
                     CWRNLHKNKEMIENKVDLGFLIGVSDYSNFKEIENTPTFTYIAGAQVATFGKLPNGME
                     KFVLPKSNYIVFTFIGKNEDSMQNVVEYIYQEWFPNSSCQFNENNLYDFVKYGEKTDE
                     NGLSEIQFWVPII"
     gene            complement(6778..7539)
                     /locus_tag="KRH23_000833"
     CDS             complement(6778..7539)
                     /locus_tag="KRH23_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HHS5224124.1"
                     /translation="MTPIIQFKNIKKQYNDKTIIDNLNLDIEKGEFLTVIGSSGSGKT
                     TLLKMINGLILPDGGNILINQTDIKNEDLIKLRRRIGYCVQGSVLFPHMTVEENISYV
                     PNLLSKKNKLEVKSAVNKWMEIVGLPNDMKVRYPSELSGGQQQRVGIARALASSPEIL
                     LMDEPFGAVDEITRKQLQKEIKEIHKKTGVTIIFITHDIYEALILGTKTLVLNHGVVQ
                     QYDTPENILNTPANQFVDQLLNIRKSIIDDDNLKE"
     gene            complement(7555..9090)
                     /locus_tag="KRH23_000834"
     CDS             complement(7555..9090)
                     /locus_tag="KRH23_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine ABC transporter
                     substrate-binding protein"
                     /protein_id="HHS5224125.1"
                     /translation="MINDILTLLSERSDFFIKLSIEHLMISIISIIIAIVLGGIIGII
                     VSEFHNSSKPILGTINFLYTIPSISMLGFLIPFSGIGNTTAVIALTIYALLPMVRNTY
                     TGITNVDKNILEAARGMGSTDFQILYKIKLPLALPVIMSGIRNMVIMTIALAGIASFI
                     GAGGLGVAIYRGITTNNTIMTITGSILIALLALIFDFILGLVEKFFQRKRKKKNRKKV
                     FAILGSLILIVTIFTSYLFNPSKTQTIHIATKPMTEQYILGEMLDILIEKNTGLNVEI
                     TQGVGGGTSNIQPAMENGEFDIYPEYTGTGWNMVLKKNELYTESMFSKLQSEYKTKLK
                     MQWTGMYGFSNSYALAVRKEVADKYNLKNITDLKDVSSKLTFGAEYDFYEREDGYTPL
                     CNTYGLNFKDTVDLDIGLKYQAINEGKIDVMPIFTTDGQYSVSDVVVLKDDKNFYPSY
                     QCGNVVRLEVLEENPELSKVFKMVGDILTDKEMAKMNYDVENNNLEPREVAREFLNKK
                     GLL"
     gene            complement(9504..11744)
                     /locus_tag="KRH23_000835"
     CDS             complement(9504..11744)
                     /locus_tag="KRH23_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HHS5224126.1"
                     /translation="MNNEFIILKGCKENNLNNISLKIPKRKITIFTGVSGSGKSSIVF
                     ETIAKESQRQLNERFSTFVRSFLPKYGEVKADCIENLSTPIIIDQSRLGGNSRSTLGT
                     ITDVNSFLRALYSRFGSEYIGNANMFSFNNIDGMCPHCHGLGKKLVPNMNQILDMNKS
                     LNEGAILLSGFGVGSWHWNIFAESGFFDINKRICDYSEVELEKFLHGKAEKIKIENAG
                     QTNMTYEGLMVKFNRLYLSREGEISEATKKKLSKLLIEDRCPICDGRRLNERVYRSLI
                     NGYNIADLTSMQIDELAEVIKSIDEPEAQPLIKGIIEKLNSIIDIGLGYLTLDRETSS
                     LSGGESQRIKMVKYLNSNLVDLMYIFDEPSVGLHPKDVYKLNNLLKKLRDKGNTIIVV
                     EHDPDVIKIADHIVDVGPKAGKYGGEVVYEGSYENLLTSGTLTGNALSKFLPIKESVR
                     EHSGYLEVKNCNKNNLKNVSIKIPKGVLTLVTGVAGAGKSTLIKDEFLKQNPSAVLID
                     QSPVSANSRSSLATYSGIMNNIRSIFSKTNGVNASLFSSNSEGACDNCKGSGIVEMNL
                     AFMESIKSTCNVCEGKKFKKEVLEYRFQGKNIIEVLEMSVLDAIEFFNLKQIKTKLQC
                     IEKMGIGYLTLGQTLDTLSGGECQRLKLASELNKESSVYILDEPTTGLHMADIENFIS
                     IIEEIVDNGNTVIIIEHNIDVIKRADWIIELGPEGGTKGGRVIFEGIPKQLCNNKISL
                     TAKYIV"
     gene            complement(12272..13072)
                     /locus_tag="KRH23_000836"
     CDS             complement(12272..13072)
                     /locus_tag="KRH23_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HHS5224127.1"
                     /translation="MESKTKYIGISILILLMIFLIAKNFNGKLEIPIPESNSRKFKSA
                     AVFYPQHQDDEVLWGGSAIVDAIKQCGVDNVYVVLVSDGSGVNVFKANTKFRNLTRKQ
                     KEELRNNEFKSALRELGVKPQNVIILADIDKKEGTHYELMEKTILDFEHKFKGNVTHI
                     AHHYKYDDHIMHRKNGEVLKKLKREGKIKDDLYFVKPKYVKYIPRNERAIYKAMDFDD
                     YNKVKSACYEYKVVNSKRKMYGIGYISAHSYFEHLLNDPELTSVLSED"
     gene            complement(13463..14338)
                     /gene="hslO"
                     /locus_tag="KRH23_000837"
     CDS             complement(13463..14338)
                     /gene="hslO"
                     /locus_tag="KRH23_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HHS5224128.1"
                     /translation="MRDYVLRATSGNGQVRAFVATTRNTVEEARRLHETTKVATAALG
                     RTLTATSIMGLMMKNDSDKLTVIIKGGGPIGTIIATSDSKGMVKGYVGNPQVEVEDYP
                     NGKLNVAAAVGTEGVVKVIKDLGLREPYNGTYPLVSGEIAEDFTYYFAVSEQTPSVVA
                     LGVLTKEDEVEFAGGFIVQLMPDAEEETIAKLEENVAKLPSITNMLKEGKSPEDILNI
                     VLDGLEPKILDTCEVGFMCECSKERVKTALVAIGKKSLAQIIEEDKKAEVGCQFCNKK
                     YMYSEEELLEILKEM"
     gene            complement(14623..15369)
                     /locus_tag="KRH23_000838"
     CDS             complement(14623..15369)
                     /locus_tag="KRH23_000838"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent DNA methyltransferase"
                     /protein_id="HHS5224129.1"
                     /translation="MSQYSDFAFVYDELMNEVDYNGWVKYIEDIIDSEGVKVKNILEL
                     ACGTGNLTIPLTKKNYDIAGIDISDEMLSVAREKAEKEGVELVLLQQDISELDFEISD
                     LDCVLCACDGFNYITYDDDLENVFSKTYELLKKDGIFIFDISSFYKLANILGNNMYGE
                     NREDIAYMWQNYFDEEENLIEMELTFFIKDECGKFERFEEIHQQRAYTEDEIVDMLEK
                     SGFKDIKYYGDFTFDKPSEESQRIFFVCKK"
     gene            complement(15356..15601)
                     /locus_tag="KRH23_000839"
     CDS             complement(15356..15601)
                     /locus_tag="KRH23_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003690 - double-stranded DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="small, acid-soluble spore protein, alpha/beta
                     type"
                     /protein_id="HHS5224130.1"
                     /translation="MKEKVQREKKITNGKNTKILTNDDIMKYEIASELGLMDKVGERG
                     WAGLTAKEAGRIGGMLTSRKKRLKKIVEEQNKKDESI"
     gene            complement(15732..16850)
                     /locus_tag="KRH23_000840"
     CDS             complement(15732..16850)
                     /locus_tag="KRH23_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HHS5224131.1"
                     /translation="MREASYLQEQLYKHRKSLNPIAEIGRKEYKTSKYIRDYLDKLGI
                     EYEVYLETGIVGVIEGKRPKKDIAFRADIDGLHSEEGVKHLCGHDGHATILLGLIEYL
                     NDNKEDLNDNIVFIFQPAEEGPGGAKALIDEGVLRKYNIDEIYGLHIYPELPEGYVGT
                     REGYFMAQIGDIDIEIVSKSGHGAMPQNGIDGIVIASNFVSSLQTIVSRNISPIDNAV
                     LTIGRIEGGARRNIIAENIKMEGTMRCFSPEVYEKMKLRVRELARGFELAYNCKVNIN
                     IIDDYIAVKNDKDLYQEFVEAIGSDTVVELEPLMISEDFSYYQKEVPGLFFMLGSRNE
                     EKGFVNGLHNINFNFDEKICVNALNVYSKLLKYKEAID"
     gene            complement(17056..18249)
                     /locus_tag="KRH23_000841"
     CDS             complement(17056..18249)
                     /locus_tag="KRH23_000841"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003941 - L-serine ammonia-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase"
                     /protein_id="HHS5224132.1"
                     /translation="MDTLKELFKIGSGPSSSHTMGPQRAAERFKNENPNAESFRAILY
                     GSLAATGKGHLTDYIIEKTIAPKKVEIVWEEDIIKDFHPNGMKFEALDKDKNVTAEWT
                     VYSVGGGTIAEEGQRNSKSNSIYHLDTMDEIVKWCKENNKTLVDFVLECEPKDIKDYI
                     KTIKDAMRKSIDDGLSTDEIIPGKLLLKRRASTFYNAYKKDKSFSTLVYAYALAASEQ
                     NASGNIIVTAPTCGSAGVIPGIFFAMQDFYNYDDEKIIEALLVAGIIGNIIKTNASIS
                     GAEVGCQGEVGAACSMAAAAVAYLKGGTIDHIEYAAEIALEHHLGMTCDPVYGYVQIP
                     CIERNAMAAQRAYDAANYALLTDGSHSVSLDQVVETMKETGIDMMDKYKETAKGGLAK
                     HFFSC"
     gene            18572..19453
                     /gene="dapA"
                     /locus_tag="KRH23_000842"
     CDS             18572..19453
                     /gene="dapA"
                     /locus_tag="KRH23_000842"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008840 - 4-hydroxy-tetrahydrodipicolinate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HHS5224133.1"
                     /translation="MLFKGSAVALVTPFTEDNNVNFEKLGELIEYHIENGTDALVVCG
                     TTGEATTMSESEIFAVIKYTVEKVNKRIPVIAGTGSNNTMLSVHMSQEAEKLGVDGLL
                     IITPYYNKTNEKGLKLHFETIANSVKLPIILYNVPGRTKVNIKPSVVAELAKIDNIVA
                     VKEASGDLAQVAEIAKLVPKDFAIYSGNDDTILPLLSLGGSGVISVLANICPKETHDL
                     VTKFFEGDIEGSKKLQLDMDALIAALFIEVNPVPVKTAMNILGFNVGDLRLPLAEMEE
                     TNLNVLKQELTNFGFKF"
     regulatory      19531..19705
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00168"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Lysine riboswitch is most abundant in Firmicutes
                     and Gammaproteobacteria where they are found upstream of a
                     number of genes involved in lysine biosynthesis, transport
                     and catabolism; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="lysine"
                     /db_xref="RFAM:RF00168"
     gene            19878..20879
                     /locus_tag="KRH23_000843"
     CDS             19878..20879
                     /locus_tag="KRH23_000843"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004073 - aspartate-semialdehyde
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HHS5224134.1"
                     /translation="MKKVNVAIVGATGMVGRTFLKVLEERNFPIENLFLFSSSKSAGS
                     KVMFCGKEYIVEELKETSFTDRGIQIALFSAGGSISEKYAPIAASNGILVVDNSSQWR
                     MNPDVPLVVPEVNPEAIKNHKGIIANPNCSTIQAMVPLKALDDKYKIKRVVYSTYQAV
                     SGSGVKGVEDLEKGMNGNPTGFYPHQISYNCLPHIDSFTENGYTKEEMKMVNETMKIL
                     DNYDLKITATTVRVPVKNGHSESINVEFNNPFELDDLVKTLEEAPGVVVVDNPAKNEY
                     PTAVEFDDRDEVFVGRIRRDFSVDNGVNLWVVADNIRKGAATNAIQIAEMALSYDLV"
     gene            20994..21881
                     /gene="dapA"
                     /locus_tag="KRH23_000844"
     CDS             20994..21881
                     /gene="dapA"
                     /locus_tag="KRH23_000844"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008840 - 4-hydroxy-tetrahydrodipicolinate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HHS5224135.1"
                     /translation="MIFKGSAVALVTPFTKDNKVDFDKLGELVEYQIANGTDAIVSCG
                     TTGEANTMTDEEQLATIKYVVEKVNKRVPVIAGSGSNDTMHSVNLSQEAEKLGVDALL
                     IITPYYNKANKAGLKRHFETIANSVKLPIILYNVPGRTCVNISPSLIVELAKIDNIVA
                     VKEASGDLGQVAEIASLVPDDFAIYSGNDDTILPLLSLGGQGVISVLANVCPQETHDL
                     VAKFFEGDIEGSRKLQLGMDALIAALFIEVNPIPVKTAMNLLGFNVGDLRLPLAEMDP
                     ANLEVLKKELVNFGLKVNA"
     gene            21948..22697
                     /gene="dapB"
                     /locus_tag="KRH23_000845"
     CDS             21948..22697
                     /gene="dapB"
                     /locus_tag="KRH23_000845"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008839 - 4-hydroxy-tetrahydrodipicolinate
                     reductase [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HHS5224136.1"
                     /translation="MLKVIATGYDGKMGKILADTIREDNELELVCVAARGLDSYEGDL
                     KIYEDMSTIVEEADVVIDFSHHSNLDNILSYVLKTKTPLVIATTGYNDDEMNKIREAA
                     KVIPVFQSYNMSLGVNVLVKLVKDAAKLLEGFDIEIIEKHHNRKVDAPSGTAVMIANA
                     IKEVLPNVENNYGRYGRSAKRQPNEVGIHAIRGGNIVGEHDALFAGDNEVLTISHQAQ
                     SRGIFASGSIAAAKYLVKQKPGFYNMDSMLG"
     gene            22957..23673
                     /gene="dapD"
                     /locus_tag="KRH23_000846"
     CDS             22957..23673
                     /gene="dapD"
                     /locus_tag="KRH23_000846"
                     /EC_number="2.3.1.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047200 - tetrahydrodipicolinate
                     N-acetyltransferase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HHS5224137.1"
                     /translation="MVNLNDAYEIARYIKEVKKKTPVKVYVNTNSLHFQSTDKFKVFG
                     NNGSYIFVGDYEDIMEVLDKHGNDITDTHVEYDRRNSAIPLKNTLSEHARIEPGAIIR
                     DMVTIEKNAVVMMGAVINIGAVIGEGSMVDMNAVIGARGTLGKNVHLGAGAVVAGVLE
                     PPSATPVIVEDDVLIGANAVILEGVRIGKGAVVAAGAVVTTDVEAGAVVAGSPAKVIK
                     MKDEKTADKTKLMEDLRNLD"
     gene            complement(23996..24985)
                     /locus_tag="KRH23_000847"
     CDS             complement(23996..24985)
                     /locus_tag="KRH23_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HHS5224138.1"
                     /translation="MLKEEKTYQEKDAKVFNGVAALIMILLFLVVSIGIMVFGIVKLD
                     SGFTGIGSLMLILGLVFIVVDFILFFGLKMINPKEAIVLVLFGNYYGTIKKEGYYWVN
                     PFCSAINPAVSRINVSKSSSDEKVDISTNSRGKKVSLKTMTLNNEKQKVNDLLGNPII
                     IGVVVIWKVIDATKAVFNVDNYNTFLSIQCDSTIRNVSRLYPYDVSEDGDEKSLRGSS
                     QEIADRLKDELQSRVDIAGIEVCEVRITHLSYAPEIAAAMLQRQQAEAIIAARKKIVE
                     GAVSMVEMALTNLSENNVVTLDEERKAAMVSNLLVVLCGNKDAQPVINSSSIY"
     gene            25425..26180
                     /gene="dapB"
                     /locus_tag="KRH23_000848"
     CDS             25425..26180
                     /gene="dapB"
                     /locus_tag="KRH23_000848"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008839 - 4-hydroxy-tetrahydrodipicolinate
                     reductase [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HHS5224139.1"
                     /translation="MLKVIISGYNGTMGRVLAECVKKDNELELVCGVARSADEKGHHS
                     DTKLYKTMTDVTEKTDVIIDFSHHETLEPILSYALKNNTPVVLATTGYDENDLNKIEE
                     ASKNIPILLSSNTSLGVNILIKLVKDASKMLEGFDIEIIEKHHNRKEDAPSGTATMIA
                     NAIREVLPESENTHGRYGRDCKRKPNEIGIHSIRGGNIISDHDVIFAGDNEVLTLSHH
                     SQSDEVFANGSIVAAKFLIGKQSGLYKMSDILG"
     gene            complement(26458..28134)
                     /gene="bclA2"
                     /locus_tag="KRH23_000849"
     CDS             complement(26458..28134)
                     /gene="bclA2"
                     /locus_tag="KRH23_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like exosporium glycoprotein BclA2"
                     /protein_id="HHS5224140.1"
                     /translation="MSDISGPSLYQDVGPTGPTGATGPTGPTGPRGATGATGANGITG
                     PTGNTGATGANGITGPTGNMGATGPNGTTGSTGPTGNTGATGANGITGPTGNTGATGA
                     NGITGPTGNKGATGANGITGSTGPTGNTGATGANGITGPTGNTGATGATGPTGLTGAT
                     GATGANGITGPTGNTGATGANGVTGATGPTGNTGATGPTGSIGATGATGTTGATGPIG
                     ATGPTGADGEVGPTGAVGATGPDGLVGPTGPTGPTGATGANGLVGPTGPTGATGANGL
                     VGPTGATGATGVAGAIGPTGAVGATGPTGADGAVGPTGVTGATGANGATGPTGAVGAT
                     GANGVAGPIGPTGPTGANGVAGATGATGATGANGATGPTGAVGATGANGVAGAIGPTG
                     ATGANGATGATGATGATGANGATGPTGATGATGVLATNNAQFTVSSSSLVNNTLVTFN
                     SSFINGTNITFPTSSTINLAVGGIYNVSFGIRATLSLAGFMSITTNFNGVAQNNFIAK
                     AVNTLTSSDVSVSLSFLVDARAAAVTLSFTFGSGTTGTSAAGYVSVYRIQ"
     gene            complement(28533..29072)
                     /gene="hpt"
                     /locus_tag="KRH23_000850"
     CDS             complement(28533..29072)
                     /gene="hpt"
                     /locus_tag="KRH23_000850"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006166 - purine ribonucleoside salvage
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HHS5224141.1"
                     /translation="MDIETKKWEVLYSEEKIKDKLRELGAIIEKDYKDKNLMVVSLLK
                     GSFIFCADLVRNINLPLRVNFMTTSSYGNNEESTGRVKVVSDVTTDIAGYDVLVVDDI
                     TDSALTMDFVLKHLKAKNPASLKCCVLLDKPSRRKVDLVPDYCGFEIEDKFVVGYGFD
                     FGDYYRNVPYIFNVTDEDR"
     gene            complement(29400..30707)
                     /locus_tag="KRH23_000851"
     CDS             complement(29400..30707)
                     /locus_tag="KRH23_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine dehydratase subunit alpha family protein"
                     /protein_id="HHS5224142.1"
                     /translation="MRDIRKELVEMLKAEVKPAVGCTEPVALALACAKAKELLGEEIV
                     ENRMLVSPSIYKNGMCVGIPGTERLGLKIAAALGIVGGHSENGLSVLETLTKEEVKIA
                     EDYMDNTPLSITPADTREKVFIEVVLKGKNHIAKVRIRTKHDNFTFLEKDGEVLLDNE
                     PKVSASNDAAEKAESLMDTVTIQELIKNVEEIDFKDIEFLLDGVKMNEEMAEYGLKQK
                     TGIGVGYGIKKSIEEGLLGNDVINYAMMLTAGASDARMAGVKMPVMSSNGSGNHGLTA
                     ILPIVAYNKKFPQSDERLAKALAISHLVTGYIKNYTGRLSAVCGCGVAASTGATAGIS
                     WLMNGTEKQIEGAIENMIADLSGMICDGAKAGCALKLSSAASAAIQSAIIAKQDCFVP
                     PLNGIVGSSVEQSIQNLGRVSDKGMSITDEIILNVMNDMNKVD"
     gene            complement(31132..32907)
                     /locus_tag="KRH23_000852"
     CDS             complement(31132..32907)
                     /locus_tag="KRH23_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54 interaction domain-containing protein"
                     /protein_id="HHS5224143.1"
                     /translation="MMIMIGLEYIKSDIQNIAEAIVSVLNIDVTIVNKELFRIAGTGV
                     YIDKIGEKVDKYTAFKKSLTEQITILIDDPKSSDICRECYKSGACVEFAEVCCPIICD
                     GDSHGVIGLIAFTKEQAQIIENNKSGLINFLGKMADLISNKLKAQIKTYELELEKKKL
                     ETLLNNMDKAVVSIDVDGKIDKYNSKFKELFNIKDSITGKNIFVELDFIKKPSINNFK
                     KDKSCSFFYKRYGYDSKGIYNINKIVLKNELKGYVIDFIDKRDAIKNYNKMNKDYRIK
                     LENIIGESVAIRNSKKEALIASKSTSTVLITGESGTGKELFARAIHNHSNRVDNPFIA
                     VNCAAIPDNLLESELFGYEEGAFTGAKKGGKLGMFEVAHKGSIFLDEIGDMSLHLQSK
                     LLRVLQEKELNKIGSKSNVSIDVRIIAATNKDLEKMVQNGTFREDLYYRLNVIPIKLP
                     SLRERKEDIPLIIKHMVKEYSKKLDKNVIDIDSRVVDAMMEYKWPGNIRELQNIIEYS
                     VNMSSSSIITMNVIPQKIKNTSVEELEVKSDRIIPLDELEKIEIIKALNKYKDYKKDK
                     ELTAKALGISRATLYRKIEKYNIIS"
     gene            complement(32904..33041)
                     /locus_tag="KRH23_000853"
     CDS             complement(32904..33041)
                     /locus_tag="KRH23_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224144.1"
                     /translation="MEINYELIIIVMLFVILMSIQFTLNKIYLILKEIRQILMLKKNK
                     E"
     gene            complement(33119..33688)
                     /locus_tag="KRH23_000854"
     CDS             complement(33119..33688)
                     /locus_tag="KRH23_000854"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HHS5224145.1"
                     /translation="MKSILCQINKQPVKAKYTSDELECFLDTIEYNVGDKILLVGHIG
                     NLGKRLRGLGTSVTILENSNYEDVCYSLVYNENCNVVKGKLEFLPFDDNQFNKIIIVD
                     QFNVITDCEKASSEIQRVLKGNGEVILEDLNLKNLKVKLNYLKHKFCGSVAKIHYPHE
                     VFNIFSRLNFDGMIKESNKLKYIYVGKRR"
     gene            complement(33872..34507)
                     /locus_tag="KRH23_000855"
     CDS             complement(33872..34507)
                     /locus_tag="KRH23_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HHS5224146.1"
                     /translation="MIAVKDENNVVNLRGELDNKLEFSHEIFGEKFYNMKIKINRLSD
                     SFDILPMTVSERLLQDIDLDKQNLVNVVGQLRSYNKTLNNKNRLVLTVFVREIKSIDE
                     ENKDPNSIFLDGYVCKEPVYRKTPLGREITDLLVAINRPYNKSDYIPSIVWGRNAKFA
                     KNLKVGDRIQLWGRVQSREYEKKIDENNVVKKMAYEVSISKIKKLDENNNE"
     gene            complement(35175..36056)
                     /locus_tag="KRH23_000856"
     CDS             complement(35175..36056)
                     /locus_tag="KRH23_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TSUP family transporter"
                     /protein_id="HHS5224147.1"
                     /translation="MVAILKALYVVFAAIFAVVFGKDVAKANKEGKLEEQSTPKVAVT
                     GFITDFFDTLGIGSFAPTIAMSKALKLNIPDKKMPGTLNVAHTIPVVTEAFIFTSIIP
                     VDGVTLVSMVVAAAVGSYIGAGIISKMDERKIQLVMGVTLALTAILMLLGHPWINVLP
                     GGGNELGLTGVKLVIGVIGNFILGALMTAGIGLYAPGMAMVYFLGMSAKVAFPIVMGS
                     CALLMPVASMKFIKEDAYTKKASVIIAICGLIGVFVAAYIVKTLPMDILKALVIVVIA
                     YTSATMIMAANKNKKTA"
     gene            complement(36176..37183)
                     /locus_tag="KRH23_000857"
     CDS             complement(36176..37183)
                     /locus_tag="KRH23_000857"
                     /EC_number="5.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline racemase"
                     /protein_id="HHS5224148.1"
                     /translation="MKFSRSIQAIDSHTAGEATRIVVGGIPNIKGNSMPEKKEYLEEN
                     LDYLRTAIMLEPRGHNDMFGSVMTQPCCPDADFGIIFMDGGGYLNMCGHGTIGAMTAA
                     IETGVVPAVEPVTHVVMEAPAGIIRGDVTVVDGKAKEVSFLNVPAFLYKEGVEVDLPG
                     VGTVKFDISFGGSFFAIIHASQLGLKIEPQNAGKLTELAMKLRDIINEKIEIQHPTLA
                     HIKTVDLVEIYDEPTHPEATYKNVVIFGQGQVDRSPCGTGTSAKLATLHAKGELKVGE
                     KFVYESILGTLFKGEIVEETKVADFNAVVPKITGSAYITGFNHFVIDEEDPLKHGFIL
                     K"
     gene            complement(37203..37676)
                     /locus_tag="KRH23_000858"
     CDS             complement(37203..37676)
                     /locus_tag="KRH23_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050485 - oxidoreductase activity, acting
                     on X-H and Y-H to form an X-Y bond, with a disulfide as
                     acceptor [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine/sarcosine/betaine reductase component B
                     subunit"
                     /protein_id="HHS5224149.1"
                     /translation="MGISTSMKNTSLHIFRDPLLDLIDNDSDIDLLGVVVVGTSEHNE
                     WKTFLATRLGRWIESLRPDGVIITLDMAGNQHIDFTNAIAEFVKSDIPTVGLTIMGAD
                     GLVITNPYLDKATIIDYKKTTGYIETEVVGDNHMDEVDVKKALAFLKLKMRKDAK"
     gene            complement(37703..38170)
                     /locus_tag="KRH23_000859"
     CDS             complement(37703..38170)
                     /locus_tag="KRH23_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050485 - oxidoreductase activity, acting
                     on X-H and Y-H to form an X-Y bond, with a disulfide as
                     acceptor [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine/sarcosine/betaine reductase component B
                     subunit"
                     /protein_id="HHS5224150.1"
                     /translation="MGIGPSTKETSLHHFRDPLLDIVESDKDVDLLGVIVVGTPDGNE
                     NKTFVGQRTAAWLEAMRVDGAIVSSDGWGNSHVDYANTFEEIGKRDIPVVGVTFNGTQ
                     AKFVVSNQYMDTIVDMNKSKEGIETEVVGENNTNEIDAKKALAFLKLKMRKHG"
     gene            complement(38185..38943)
                     /gene="prdD"
                     /locus_tag="KRH23_000860"
     CDS             complement(38185..38943)
                     /gene="prdD"
                     /locus_tag="KRH23_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline reductase cluster protein PrdD"
                     /protein_id="HHS5224151.1"
                     /translation="MEEKIMRRLVIKPFHMNEVNFGSKTSIKKDVLTIDLSSIDEIKE
                     REELITDIKVDIIKPGDYDREINTIMDIIPISTKVLGRLGEGITHTLTGVYVMLTGAD
                     EDGNQMHEFGSSEGILKDQMVFGRYGTPSVEDYIIHVDVTLKGGLPFERTLPLAAFRA
                     CDDFIQEIRASLKMEDGRNATQVREYFDKIRPNAKKVVIVKQIAGQGAMYDNQLFSKE
                     PSGFEGGTSIIDMGNVPMIISPNEYRDGALRAMT"
     gene            complement(39023..39748)
                     /gene="prdB"
                     /locus_tag="KRH23_000861"
     CDS             complement(39023..39748)
                     /gene="prdB"
                     /locus_tag="KRH23_000861"
                     /EC_number="1.21.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050002 - D-proline reductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_except=(pos:complement(39296..39298),aa:Sec)
                     /transl_table=11
                     /product="D-proline reductase (dithiol) protein PrdB"
                     /protein_id="HHS5224152.1"
                     /translation="MSLTTVQGLQSEIFVPITPPPVWTPVTKELKDMTIALATAAGVH
                     LKSDKRFNLAGDTTFRAIPNTATVDEMMVSHGGYDNGDVNKDINCMFPIDRLHELAAE
                     GFIKGVAPMHYAFMGGGGNQHVFTEETGPAIAAKLKEEGVDGVVMTAGUGTCHRTAVI
                     VQRAIEEAGIPTIIIAALPPVVRQNGTPRAVAPLVPMGANAGEPHNIEMQTHILRDTL
                     EQLVAIPSAGKIVPLPYEYKAHV"
     gene            complement(39786..40070)
                     /locus_tag="KRH23_000862"
     CDS             complement(39786..40070)
                     /locus_tag="KRH23_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBO2463/CBO2479 domain-containing protein"
                     /protein_id="HHS5224153.1"
                     /translation="MDRLKYISSETFYEGIIVDIKGGGVTIDLKGRLGQFKIPNRMLI
                     TDYELKIGQEVGFMLSYPEVLSPEPNQEYVENIRREKEKQAEMQSKQEEK"
     gene            complement(40151..42031)
                     /gene="prdA"
                     /locus_tag="KRH23_000863"
     CDS             complement(40151..42031)
                     /gene="prdA"
                     /locus_tag="KRH23_000863"
                     /EC_number="1.21.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050002 - D-proline reductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-proline reductase (dithiol) proprotein PrdA"
                     /protein_id="HHS5224154.1"
                     /translation="MSITLETAQAHANDPAVCCCRFEAGTIIAPENLEDPAIFADLED
                     SGLLTIPENGLTIGQVLGAKLKETLDALSPMTTDNVEGYKAGEAKEEVVEETVEEAAP
                     VSEAAVVPVSTGVAGETVKIHIGEGKNISLEIPLSVAGQAGVAAPVANVAAPVASAAA
                     EVAPKVEEKKLLRSLTKKHFKIDKVEFADETKIEGTTLYIRNAEEICKEANETQELVV
                     DMKLEIITPDKYETYSEAVLDIQPIATKEEGELGSGITRVIDGAVMVLTGTDEDGVQI
                     GEFGSSEGELNTTIMWGRPGAADKGEIFIKGQVTIKAGTNMERPGPLAAHRAFDYVTQ
                     EIREALKKVDNSLVVDEEVIEQYRREGKKKVVVIKEIMGQGAMHDNLILPVEPVGTLG
                     AQPNVDLGNMPVVLSPLEVLDGGIHALTCIGPASKEMSRHYWREPLVIRAMEDEEIDL
                     VGVVFVGSPQVNAEKFYVSKRLGMLVEAMEVDGAVVTTEGFGNNHIDFASHIEQIGMR
                     GIPVVGVSFSAVQGALVVGNKYMTHMVDNNKSKQGIENEILSNNTLAPEDAVRIMAML
                     KNAIEGVEVKAPERKWNPNVKLNNIEAIEKVTGEKIVLEENEQSLPMSKKRREIYEKD
                     EN"
     gene            complement(42460..44220)
                     /gene="prdR"
                     /locus_tag="KRH23_000864"
     CDS             complement(42460..44220)
                     /gene="prdR"
                     /locus_tag="KRH23_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54 dependent transcriptional regulator
                     PrdR"
                     /protein_id="HHS5224155.1"
                     /translation="MFSIPEVKKVEEVMDTKFTTIDEDTRIEDAIKEMIKSNTKTLMV
                     IDSSDQLKGIISMTDIHNLYEMHKKYEGQPVKLIMKKDVIYVNEGLTLDECRDIMILK
                     NIGILPVLRDNKIIGVLKQEHIRDYLYMHLEDYGLTLKYIIGQIKEGICAINNEGVVI
                     LWNKFMEERYDIKSEDIVGRPMNEFLENTISEKVLNSKVGMSDLYFTDKKENMYALVH
                     ANPIFYKEEFIGVVCTEVDVTEAKILALELEKVNDTLKYLKNEVKNLSKGSFDKILGK
                     SYKLEKSKAIAKQVARTNSSIFIWGESGTGKEVFARAIHDYSERKGQFIPVNCSAIPN
                     ELFESEFFGYESGAFTGASKKGRIGIFELAKDGTVFLDEIADLPLSMQAKLLRVLQEK
                     EIRRVGGDTTIKINPRIISATNKDLSKMVKAEKFREDLYYRLNVVEIKIPPLRERKED
                     IGLLVHSFLEEICKQNNKPVLTISKDVIDIFQNYRWKGNIRELKNTIENIVVLSQNSK
                     IDVDDVPSYMMDSTNNSTEEEEYPLDLTKATQKIEIKNITKALKMSNGNKAKAAKILN
                     IPRTTLYYKIDQYKIDVSKI"
     gene            complement(44627..46843)
                     /locus_tag="KRH23_000865"
     CDS             complement(44627..46843)
                     /locus_tag="KRH23_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-Gln thioester bond-forming surface protein"
                     /protein_id="HHS5224156.1"
                     /translation="MKTKIKKSSIISLVIAFSMVFTAFTPIVSYADEVTSNDTILNGE
                     EQSNDQTPDVEKPSDGQIPDGEKPSDSQVPDVEKPSDGQIPDVEKPSDGQIPDVEKPS
                     DGQIPDGEKPSDGQIPDGEKPSDGQIPDGEKPSDGQIPDGEKPSDGQMPDGEKPSDSQ
                     TPDVEKPLDEQTPEEEKPLEEEIVIEEMSLKQDIDKILDMTLSQINKIVYNFWEDEED
                     VKADEQSEINQVFTSEDSFISLWYDKKAKVKNSCLLKEIDGSDRPYHDLRFDDITKTL
                     TFDYVIKGLVGASSKDDKYVIEGEDGEQTAFCYNNHLRPPSSNGKSPYLPAEDFNGQE
                     NQNEEAVKSILYAGSEFDGFGYKQQFNLGEEENDIMTYSATQSAIWIILGQIDEQERL
                     KQYQGSIDLCDKLIEIAKTEEERAEYQKRKEVAINTKAYLEALLKAGREELKPNDTGK
                     PSLSNGLTKINFEKNEDGTYETEAVALVGYSGVVKLKLPDGVTAYDVDGNIIGTGEVE
                     ISTQQKFKLKSVGKPDAKANISAVSYDYIFPKAIQYYKAVLDLGQKDHSSSLPSSKQN
                     LLSYTIEKKNGQEVNFNIGLPTDDDDVVNPPVPPIDDDVVNPPVPPTDDTNGHKPKPS
                     PPIDDTVINPPVPPMDDTIINPPVPPTEDAVLNPPVPPMEDAVLNPPVPPTDDTVLNP
                     PVPPVSDTVEKTPELSRDDTIVKSPKTGDETQLMSYVFISVIAICGLAYQCKIKRN"
     gene            complement(46998..47126)
                     /locus_tag="KRH23_000866"
     CDS             complement(46998..47126)
                     /locus_tag="KRH23_000866"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224157.1"
                     /translation="MDNQQVSFEKKKLQRLERNLVPTSVGKWGVPNLWLGNDIVCA"
     regulatory      complement(47425..47510)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF01786"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cyclic di-GMP riboswitch class II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01786"
     gene            complement(47913..49226)
                     /gene="prdC"
                     /locus_tag="KRH23_000867"
     CDS             complement(47913..49226)
                     /gene="prdC"
                     /locus_tag="KRH23_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline reductase-associated electron transfer
                     protein PrdC"
                     /protein_id="HHS5224158.1"
                     /translation="MNKLYSILLKQHVGGPDKPVVSVGDVVKKGTLIAEPTGLGANIY
                     ASVSGKISEINDQAIVIEADEVQEDTFEPLKGEGILDLIKEAGVVGMGGAGFPTHVKL
                     NIDLNGGTILANAAECEPLLAHNIKEIEERPEIVYQGIKYAMEVTNAGKGMLAIKSKH
                     PKAIEAFKKVIKPGDNIEVAELVDMYPMGEERAIVRDVLGKLLEPTQLPSEANAVVIN
                     VETLTRIVEAVEQKRPVISKNITVVGQLNSGKESIVFEDVPIGTTVGELIERAGGIKG
                     EYGEIILGGPFTGKATTLDAPITKTSGGIIVTMPFVNEKRKMGLLVCACGPNEERMRD
                     IATKMGVTDIVSVQKCKQAQEIKGALKCENPGHCPGQAQKCIEFKKAGAEVILIGNCT
                     DCSNTVMGSAPKLKLGVYHITDHVMRTVNHPLIRRIKGDVRLKIK"
     gene            complement(49615..50379)
                     /locus_tag="KRH23_000868"
     CDS             complement(49615..50379)
                     /locus_tag="KRH23_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HHS5224159.1"
                     /translation="MKREVKRTKALIYSVLFFSLLLVLIFVFVYGIKYICSKSDNSKM
                     PIYKVDTNEKKIALSFDVAWGTDNMDDILKILDKHNVKATFFLVGSWVDDNEEIVKAI
                     DEKGHEIGNHSNTHANLKEISKEDITKEIETTSEKIYNITGKKTNLFRPPFGDVNNKA
                     MDICSDLGYKVIKWDVDSIDWKELGPNHVIEKVIKESQPGSIVLFHANINDVDNYLDT
                     IISRLKKDGYSLVKISDLLYKDNYVVDSNGVQKTKN"
     gene            50670..50873
                     /locus_tag="KRH23_000869"
     CDS             50670..50873
                     /locus_tag="KRH23_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003690 - double-stranded DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="small, acid-soluble spore protein, alpha/beta
                     type"
                     /protein_id="HHS5224160.1"
                     /translation="MSNSNRTVVPEAKAALNQMKLEIANEIGLSNYENIDKGNLTARE
                     NGYVGGYMTKKLVEMAERQMAGK"
     gene            51064..51600
                     /locus_tag="KRH23_000870"
     CDS             51064..51600
                     /locus_tag="KRH23_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4364 family protein"
                     /protein_id="HHS5224161.1"
                     /translation="MFENSSEELAYHKLLILYILEKIKMDLTNSQITQVVLETEMMNY
                     FSLQQLLSQLMESKFLTTYKDSDREYYALTQRGVESLEYFFNRIPTSVTEKIDKYIDS
                     NKENLLADTQVKSSFVKQSDNEFIVNLRVIENQSNLIDLNLNVSSEKQAKLICNNWKN
                     NASYMYAEVIDLLIRDIH"
     gene            complement(51604..52470)
                     /locus_tag="KRH23_000871"
     CDS             complement(51604..52470)
                     /locus_tag="KRH23_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YncE family protein"
                     /protein_id="HHS5224162.1"
                     /translation="MKIYISNYLSKSISIVDYSTLELEKEIVLEDNIYPHHFCIEKEK
                     NLIYIPSSSNGILYVLDLSNDKIIDTVSIGGSLSQVVLSDNELFVANEDSNSIYVLDK
                     NTLNPIGIIGVDNMPHGFDFDRESKKLYVPCINSIVCIDTINKNIQKKINMDFRAWHI
                     ELDKQKKEMYISTLDGKLIIIDEVSMDIKKVLYEFLLPVEIRFNYSGKKVYVADLGYN
                     NVRILDYTTSRYIGNIEINGIPQGLEISKDEKLLFVSDTQENSVKVYETANNKLIKEI
                     KVGKEPTTIICL"
     gene            52618..52863
                     /locus_tag="KRH23_000872"
     CDS             52618..52863
                     /locus_tag="KRH23_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03905 family TSCPD domain-containing
                     protein"
                     /protein_id="HHS5224163.1"
                     /translation="MKVTFNPSGVCCREMIFEVDENNVIVDAEFIGGCNGNLSGLRSL
                     IIGQNALEVADKLNGIDCGGKGTSCPDQLSKAIRQSI"
     gene            complement(52977..54275)
                     /locus_tag="KRH23_000873"
     CDS             complement(52977..54275)
                     /locus_tag="KRH23_000873"
                     /EC_number="6.3.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004326 - tetrahydrofolylpolyglutamate
                     synthase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008841 - dihydrofolate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HHS5224164.1"
                     /translation="MKYEEALEYISQTNKFGIRLGLENIGKLLELLGNPQETLNIIHV
                     AGTNGKGSVCSFVSNILRECGYKVGLYTSPYLETFTERIRVNGQNIPQDDVARIIELI
                     KEKIEIMVKEGYAYPTEFEVVTAMAFYYYSEQKVDFVALEVGLGGRYDATNIITKSLV
                     SVIVSISLDHTGILGDTIEKIAYEKAGIIKENGVVLVYDQTDEAKDVIKSVCKEKKAK
                     YIEVDFDDINIKKSDINSQIYDCTVMKETYRDLEIKLIGEHQINNSILAISVIKYLKD
                     INKLANINEESIRKGLINTKWPGRIEKIKENPIFIIDGAHNEDGAKSLAKALDKNFKG
                     RKLTLLIGMLEDKDIDSVLEILLPHFNKVITTTPNNPRAINSDILREKVLKYVDDVTS
                     KHEIEDAVNYTLETSSEDDIIISAGSLYMIGTVRTLIKKL"
     gene            complement(54408..55421)
                     /locus_tag="KRH23_000874"
     CDS             complement(54408..55421)
                     /locus_tag="KRH23_000874"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family peptidase"
                     /protein_id="HHS5224165.1"
                     /translation="MNNKVKVAVLDTGIDKEHDYLKDNLVGGIAFECMHDYIFISDKF
                     DDEDGHGTACASIIKKEYEDVELFVIKILRKDGITNIKVLEEALRYLLDTNIRLINLS
                     LSVIGVESVKGLFEVCYELFRKGKIIVCSLANDFDLSYPAMFNNVIGVRGFTLDGDDS
                     FWYNKKYDVQCVMDSNSYISCDINNSYRLPPKCNSYLSAKLTGKIAKILSEKPGITIS
                     DLNDKLESLATRNHWDSCDFDECSRIVNFKLDLYDKENALFMKVADVVRDCLDIEENN
                     EKLFKGSLFNKEIGLVYDNCFNLLKKLEHRFDIKFNYMDISKYDLVSIYTLTELVERY
                     KNL"
     gene            complement(56485..57195)
                     /gene="rgaR"
                     /locus_tag="KRH23_000875"
     CDS             complement(56485..57195)
                     /gene="rgaR"
                     /locus_tag="KRH23_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RgaR"
                     /protein_id="HHS5224166.1"
                     /translation="MFRVVICDDEKIQRSILKEFTEKLLSERCLNYQILEFSCGEDLI
                     SKYPEKIDIIFLDIQMKDINGIEVAKKIRKFDEKVEIIFTTAFSEYAPQGYEVRAYRY
                     LVKPIEYSNFAMGVNLCIDNLQRKKERYIVLNSKKGFNRILIDSILYVETVKRDLVVH
                     TIGRDYKANMSMKQAEKLLCENGFFRCHTSFIVNLRRIEDLRDNMITINEQFIPISKY
                     RLKDLKVALTSLLCDIMY"
     gene            complement(57620..60286)
                     /locus_tag="KRH23_000876"
     CDS             complement(57620..60286)
                     /locus_tag="KRH23_000876"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0004832 - valine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006438 - valyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HHS5224167.1"
                     /translation="MENTNLSKTYNPKDFEARLYKKWMDEGYFKSKPNPDKKPFTIMM
                     PPPNITGQLHMGHALDHTLQDILIRWKRMDGYEAFWLPGTDHASIATEVKVVERIKKQ
                     EGKTKYEIGREEFLKRAWEWKDEFGGKISNQLKQLGDSCDWDKERFTMDEGCNEAVIE
                     FFVSLYEKGHIYRGNRIINWCPDCKTTLSDAEVEHEEHDGNFYHIKYPLKDSEDFLEI
                     ATTRPETMIGDTGIAVNPEDDRYKHLIGKTAILPLVGRELPIVADSYVDLEFGTGAVK
                     MTPAHDPNDFEVGLRHNLEQLNTMNEDGTMNEVCGKYEGMDRFECRKAIVADLKEQGY
                     LIKIKEHNHNVGTCYRCHTVVEPRLSEQWFVKMEELAKPAIDILKKGELEFVPDKFDK
                     TYLQWLENIRDWCISRQLWWGHQIPAYYCQECGEIVVARKMPDKCPKCGSTHFKQDED
                     ALDTWFSSALWPFSTLGWPNKTEALDYYYPTSVLVTGYDIIFFWVVRMAFAGMFCMNE
                     KPFDHVLVHGLVRDSQGRKMSKSLGNGIDPLEIIEQYGADALRFTLTTGNSPGNDMRF
                     YMERVEFARNFANKLWNASRFVFMNIDEDIIKNMTRESVKEDLTLADKWIISRANNIV
                     KEATNNMDKFDLGIALQKIYDFTWSEYCDWYIEMVKPRLYGEDANAKSAALYTLTYVL
                     EKILKLLHPYMPFITEEIYTHLPTVEGCIIVSEWPKYNEEDNMAEEEDMMNLLMEGIR
                     SIRNVRAEMNVPPSKKAKLIIIPSEEKIEAIELGKDYFITLASASNVEIAKDKSNVPE
                     DAVGVVIDGVEIFIPLNELVDFEKEIERLSKEKKKLEGEIKRVNGKLANQGFLAKAPE
                     SLIEEEKAKKEKFEEMIKSVEERLTNLESKIK"
     misc_binding    complement(60362..60624)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(60920..61747)
                     /locus_tag="KRH23_000877"
     CDS             complement(60920..61747)
                     /locus_tag="KRH23_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HHS5224168.1"
                     /translation="MKIKDNKAVFHVFIRIFIIAVLILTGTLLEEKINNVPVENISSK
                     GENTLELLSQSNTLGEIIYKASQEETKGPGATSEKVAYITIDDGPSKYTNALLDILKE
                     NDVKATFFMLNQNMKNHKEEVRRVLEEENSIGFHSVSHDIHKLYKSPEVTVGEFNTCN
                     NTLQEITGQSSKLIRLPYGSKPYMPEGSYNKLMANDYLIWDWNLDTQDWKSSTSQIVS
                     NILYYGRKRDELVVLIHEKEQSLNALNNIIRILKERGYTILPITENITPKNFWQENL"
     gene            complement(61795..63231)
                     /locus_tag="KRH23_000878"
     CDS             complement(61795..63231)
                     /locus_tag="KRH23_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[Fe-Fe] hydrogenase large subunit C-terminal
                     domain-containing protein"
                     /protein_id="HHS5224169.1"
                     /translation="MNTRNDNSKILEIYKMKLFGELVKAVWNDDIEDIENLPNKILNE
                     DLKDNLNNYFSGKFDKDTMVNLIRVTMGLDVTGDTDKNLKESLHEAVNLDEVKRPIIS
                     VISDACKYCDENNKEDESCKIRSKHINCNEEDVCSACGDCVSRCKLGAISDKIEFIPM
                     IKLLKDIKSPVYAIVAPAFVGQFGKDVNPGKLRTALKKIGFEDMIEVALAADMLTAKE
                     AYDYYEHMKKDEEGCFITSCCCPIWVSLIQNSFPQILENVSPSVSPMIACGRAVKILN
                     PDAKVVFIGPCMAKKKEAMLEDIKDAVDFVLTFKELQEIFDALELNPAIMDESNRVEA
                     SLSGRVYARTGGVSKAVKLSVRRIDKNIKFEEKAFEGTKECMDGLKKVLNKEIEATFI
                     EGMGCVGGCVGGPKRILSVEEGTKNVDEYSESTNMETPFDNLNVLQFLTSLGIKRVES
                     LGEKEEEKVKKIFSRDIKSNKKENKYKK"
     gene            complement(63318..64187)
                     /locus_tag="KRH23_000879"
     CDS             complement(63318..64187)
                     /locus_tag="KRH23_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HHS5224170.1"
                     /translation="MKLQKMGMRTIKTGISVTLCMILGDYLVENMFYSLVACIISVQD
                     TVKGSLKTGINRVEGTILGGIIGFIFAIIKAGDPFLCGLGVMCSIYLCNLFKIKSVVV
                     ACVTFLAIHLGVGNSDPVYYSLHRVLDTSVGVLFGVLVNYYVARPNYLNSVIDEFKKI
                     EELSMLLIEDKILRKENLNVEKFEEEVEKLEEIYSKLIDELDYSLSETNVEKIENALR
                     ICREIHFHMQSIELLENKLYLKEHTYKYLKKTYNVDKLDWNIDEEKSPVFNYHLMKIM
                     IEIELLRKLNKSY"
     gene            complement(64345..64998)
                     /gene="phoU"
                     /locus_tag="KRH23_000880"
     CDS             complement(64345..64998)
                     /gene="phoU"
                     /locus_tag="KRH23_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA];
                     GO_process: GO:0030643 - intracellular phosphate ion
                     homeostasis [Evidence IEA];
                     GO_process: GO:0045936 - negative regulation of phosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HHS5224171.1"
                     /translation="MVNNSLDISIDTLKEQTVLMMEKCEEAIEKSVTCMIEKDLEGAR
                     KVVEDDEEINKLREEIRDKSIELIVLKQPMARDLRFIYSLGNISIELERIGDYAANIA
                     REMLKIGGEAYIKELIDIPKMAKECKSMMSQTREALILFDASIAYDVGIKDDIVDGLY
                     EQVQIDCLKIMHENSNTIDQGVKLLLIGRYLERIGDHITNVCEKIIFAIEGKMVEIG"
     gene            complement(65026..65790)
                     /gene="pstB"
                     /locus_tag="KRH23_000881"
     CDS             complement(65026..65790)
                     /gene="pstB"
                     /locus_tag="KRH23_000881"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HHS5224172.1"
                     /translation="MELIDKIKMSVKDLDLFYGDKQALKKINMDIKENKVTALIGPSG
                     CGKSTFIRTLNRMNDLIEDVTIKGNISVDGEDIYTSDDVINLRTKVGMVFQKPNPFPM
                     SIYDNVAYGPRTHGLRDKKQLDKIVEESLKGAAIWDEVKDRLKSSALGLSGGQQQRIC
                     IARAIAMRPEVILMDEPTSALDPISTLKVEELIEDLKKDYTIVIVTHNMQQAARISDE
                     TAFFLNGEVIEFSDTKTMFTTPVDKRTEDYITGRFG"
     gene            complement(65809..66633)
                     /gene="pstA"
                     /locus_tag="KRH23_000882"
     CDS             complement(65809..66633)
                     /gene="pstA"
                     /locus_tag="KRH23_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HHS5224173.1"
                     /translation="MRKFKENLLKSLVYLSALFTIVSLVVIVGFIFIKGIGNMNFNFL
                     FSNYSASGDGGILPMIITTLYTVVVSIVVATPIGILAAIYLQEYAKKGKAVTAIRFAT
                     ESLSGIPSIVYGLFGGIFFVVTLKMGYSIVAGSLTVAIIILPVIIRTTEEALKTVPQA
                     YRESSLALGATKFQTLYKVVLPSAIPGILSGVILSVGRIIGESAAILLTAGTVAKMPG
                     GIFDSARTLTVHSYLLTKESGDIATAASIGIVLIVIVLALNMLARFVAKKLNKANY"
     gene            complement(66635..67552)
                     /gene="pstC"
                     /locus_tag="KRH23_000883"
     CDS             complement(66635..67552)
                     /gene="pstC"
                     /locus_tag="KRH23_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HHS5224174.1"
                     /translation="MIVKSRLVGLEKNDNNGNKTKYVIEKVAKNIFLLSALVAVASLL
                     LIIGFVFYKGLRPFIFEGYSFIDFLTGADWVPSANKFGISSMIVASIFATLGALVIGV
                     PVGILTSVFIAEVAPKRLAKIMSPAVELLAGIPSVLYGVFGLAVIVPTIQSIFNLPKG
                     QSLLAIVIVLAVMMLPTIISVSETAIRAVPKAYKEGSLALGASKIETIFKVVLPAAKS
                     GVLAAVVLGVGRALGETMAVILVAGNSPVMPTAITDSVRPLTTNIALEMGYAFGTHQE
                     MLFATGVVLFTFILILNLVLNKLSNKAVN"
     gene            complement(67933..68379)
                     /locus_tag="KRH23_000884"
     CDS             complement(67933..68379)
                     /locus_tag="KRH23_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224175.1"
                     /translation="MAISDLAFGTECLKTSFQMLFSVISLVNINLLQAQILIAIGGLI
                     SILAMVSLTLFLSAKCKDSLTSMLIAFSICLIPMGIGVSWIGYLLPPGGIGFKISLLY
                     QMTSFNFLHLGGMSFWTPHIILFFSVIEIPIFIFLAIRTYCKHQVS"
     gene            complement(69103..69489)
                     /locus_tag="KRH23_000885"
     CDS             complement(69103..69489)
                     /locus_tag="KRH23_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HHS5224176.1"
                     /translation="MLNKKLPDSEFKIMKYIWNTGYKTVISKDVADEMEKIYKWKQTT
                     TLTLLLRLTKRGFLASQKIGKHTHYTILIKEKEYLKSETKKLFGGLHNNPLSQLISKL
                     HDKEEVSIDKIDALEEWLRSLQEDEE"
     gene            complement(69529..69834)
                     /locus_tag="KRH23_000886"
                     /pseudo
     CDS             complement(69529..69834)
                     /locus_tag="KRH23_000886"
                     /inference="COORDINATES: protein motif:HMM:NF015898.6"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
     regulatory      70126..70223
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            70278..70454
                     /locus_tag="KRH23_000887"
     CDS             70278..70454
                     /locus_tag="KRH23_000887"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224177.1"
                     /translation="MFKNKMDKCTHMLTAYISSSYDYCNFLDTQLDDFILEYGENVVE
                     SCLHQVMVLVSKYN"
     gene            complement(70673..70849)
                     /locus_tag="KRH23_000888"
     CDS             complement(70673..70849)
                     /locus_tag="KRH23_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224178.1"
                     /translation="MKTLMFILVIAYYITIVIKSITTIVKSITRLLDSISRLKESLHK
                     LRNRPDGNQDDFNE"
     gene            71105..71293
                     /locus_tag="KRH23_000889"
     CDS             71105..71293
                     /locus_tag="KRH23_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224179.1"
                     /translation="MTKTILCDYCNKGINKDDNKYITFHKKSHMKTNICINCALNLID
                     KDKLNENIINNQHGYSKK"
     gene            complement(71692..72162)
                     /locus_tag="KRH23_000890"
     CDS             complement(71692..72162)
                     /locus_tag="KRH23_000890"
                     /inference="COORDINATES: protein motif:HMM:NF042490.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6650 family protein"
                     /protein_id="HHS5224180.1"
                     /translation="MRKIEIFNKLTGISCPIFGVSWDPPESERKIARRIIVFLEPKRV
                     LYSPYEYETIEPVVNSVIEIKNYLTSELMNVNEKSELQGYIRAMRNSCNKFLSKCKDD
                     NNFRVQACCAGNISNWIFTSAIGEMRGNFGIMIGQIVSAYGISIEDDLANIIPE"
     gene            complement(72489..73319)
                     /locus_tag="KRH23_000891"
     CDS             complement(72489..73319)
                     /locus_tag="KRH23_000891"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003415961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008745 - N-acetylmuramoyl-L-alanine
                     amidase activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HHS5224181.1"
                     /translation="MKICITVGHSILKSGACTSADGVVNEYQYNKSLAPVLADTFRKE
                     GHKADVIICPEKQFKTKNEEKSYKIPRVNSGGYDLLIELHLNASNGQGKGSEVLYYSN
                     KGLEYATRICDKLGTVFKNRGAKLDKSLYILNSSKPTAILIESFFCDNKEDYEKAKKL
                     GYEGMAKLIVEGVLNKSIESNEVKQMYKHTIVYSGDDRVSADILGLYYKREKESYLVT
                     DIKDYKPHRTQNLYVIGGVTCNKMKEMSKTTGEKFTQLYGNDVWSTLDKAIEFVKEKL
                     "
     gene            complement(73319..73576)
                     /locus_tag="KRH23_000892"
     CDS             complement(73319..73576)
                     /locus_tag="KRH23_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HHS5224182.1"
                     /translation="MDNLISFIPEQLLILVAALSIIGKGCKKYKQLDNKYIPVVLLIL
                     GIGFSIWMLGLSPVAVLQGVICWGISIGINQTYKQLKEENK"
     gene            complement(73596..73826)
                     /locus_tag="KRH23_000893"
     CDS             complement(73596..73826)
                     /locus_tag="KRH23_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin XhlA family protein"
                     /protein_id="HHS5224183.1"
                     /translation="MNEELFEADLKRHETRINKHGEEIDELKIANIESKAELKALCEN
                     LNSLTSMLKWLIGTMITTLVGFFIFAVQRGIF"
     gene            complement(73858..73995)
                     /locus_tag="KRH23_000894"
     CDS             complement(73858..73995)
                     /locus_tag="KRH23_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HHS5224184.1"
                     /translation="MNWYKIIADFYKNGNWTKEQVKTAVEKNKITASEYKEITGEDYI
                     V"
     gene            complement(73997..74296)
                     /locus_tag="KRH23_000895"
     CDS             complement(73997..74296)
                     /locus_tag="KRH23_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224185.1"
                     /translation="MIYLGNLMDTEEQNIKYVGMIHYKPSILGEEDLKSGILVDELPV
                     QQYIENKEAKLFINIDTKEVFYRYTDIKSSMEDKVNSTEQTIADLTFQLMSNGVI"
     gene            complement(74296..75555)
                     /locus_tag="KRH23_000896"
     CDS             complement(74296..75555)
                     /locus_tag="KRH23_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224186.1"
                     /translation="MTFKELVNKVRNLVLEAEKVTIEDTENNFTSDNVEDALKEVFQS
                     GVDAKNNVVTALNSKGAEVTTSDTWEEIKNKINDSKCSFALFETTFTNKRFIINKIFD
                     EDVKEMTLFHNDIDCYFIVAKFYIYKMDSNFNLIYKNRLTYNPDGAYIDENYIYIGDV
                     YNLSKYDKESGNLVSSRTNIGCLYMCGDENYLYAVVTSGLGGVRPSEKFIKIDKLNLS
                     TIIENGDGTDNSTYEFRYHEKFVMNSNNIYFMKAKHKKNSYNDYYQYLCKMNPNTLNI
                     DTQLTIYNNVPYKDYVKGFVFIGDKIYLTKQRNIESALSKTLSVVDKDLNLTELGADT
                     YSPNRDLITDGTYLYSVSAWSSPSRFDLEKINVSDFKKITEYSCHSDLKSFVTLCNNK
                     ICFTSSSGICLAILVSNILIQKEGEEL"
     gene            complement(75589..75771)
                     /locus_tag="KRH23_000897"
     CDS             complement(75589..75771)
                     /locus_tag="KRH23_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224187.1"
                     /translation="MNINNVVVRILAERILSRGLNPLKNREFELDDVTNTEYRKAVED
                     YIIKQSGVVEGIEPTA"
     gene            complement(75771..76064)
                     /locus_tag="KRH23_000898"
     CDS             complement(75771..76064)
                     /locus_tag="KRH23_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224188.1"
                     /translation="MNRANRIIYDQTGKILLQTGEATGDILEHDEITELHCIDIEYGS
                     IDYTKNRITGINIETKEPILEEIPIFVSEEEKRIQELENQLLLNENEKVGGLL"
     gene            complement(76078..77766)
                     /locus_tag="KRH23_000899"
     CDS             complement(76078..77766)
                     /locus_tag="KRH23_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine rich domain-containing protein"
                     /protein_id="HHS5224189.1"
                     /translation="MQTEWNFGYNGSPQSVILKPGKYKFECWGSSGGINNSSWHTDAK
                     GGYSKGEITLKKQTTLYVYVGESGFASSSTSNNTKSGFNGGGKGYLNQQVMGTYYSMY
                     GGGATDIRLVGGAWDNEQGLLSRIIVAGGGGGSYSPYTGGAGGGLAGGTGYSANDRHR
                     PGGTQYQGGIGRVSTENGSFGKGCSAKDSTGEGGGGGWFGGAGMNGVGAGGGGSGYIL
                     TKDSYKPTGYTPTSEYYFDNVVMESGGNTAGAYGYALITLLQALPFLTVSSYNSTTAT
                     FKADHTDPALLTKIEYFIDDVLKETITTDLTLEKTINYTLEDNALHTLKIVVTDSNNA
                     TAEKVLSISKNIMPLPENVNLNDISTKLTEVNAGFKTGKTSIINTLALKNIEASLNNT
                     LVELSEKIKTSFDSSDASVQDLMNQLTQSNNTITQLNTKYQYFSGVTTLIGNSICIAN
                     FYGKASGMYPGYWIRVGGFKSVPNIFIAECEYIYDGKFYKHLIFASCGVFTKDFTIRL
                     CFSREIDVNTFSVKGDIFNIEEQDVWYNTNLGLNLPAYNTNIPVNFNWCAIKFK"
     gene            complement(77783..78805)
                     /locus_tag="KRH23_000900"
     CDS             complement(77783..78805)
                     /locus_tag="KRH23_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HHS5224190.1"
                     /translation="MADEQFYTILTNIGKAKIANAGMLGKSVILEKIQAGDGGGNYYN
                     PTEDQTALKNKVWEGNINAFDNDENNPNWIIATACIPGSIGGFTVREMGLIDNEGDMI
                     AVCKSPETYKPKVDNGAMKDLYLKFIIEVSNVEKVTLVVDPTAIFLTKKDEEKILTNI
                     NKLDTKIDTTKTELTSNIETTKTELNTRIDTENEKQNIKIDQLIAGGSNVASTQIITI
                     DDWVEDAENGFKATVTHSLLTQRIVVNIIDATTKENAVTNFKIIDDNSIEVRSETRSE
                     LNVYVINGNAETHFINATVDDNRVSEMTTYSSKKIEDRFVNLEEKVNGGLSNIATSVN
                     ELITYC"
     gene            complement(78818..79447)
                     /locus_tag="KRH23_000901"
     CDS             complement(78818..79447)
                     /locus_tag="KRH23_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YmfQ family protein"
                     /protein_id="HHS5224191.1"
                     /translation="MIASKKGKEMLLTLSPIYEQSIIMQSLYEAIGSEFDNLELLNKE
                     IELQLFPQSATWGLEFWENRVGLSTNIDEDIEARRRKVIAKLQSKYIMTPKRMAMILQ
                     SYTGANIKINENISPYTFGVELTSTQGFPKDLEDLYKRVNVIKPSHLAVSYKLVSLLK
                     SKTYFAQTAIMSEEITVYPYTSKEVKASVKAKFALAHNMSSETLTVYPR"
     gene            complement(79444..80580)
                     /locus_tag="KRH23_000902"
     CDS             complement(79444..80580)
                     /locus_tag="KRH23_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="baseplate J/gp47 family protein"
                     /protein_id="HHS5224192.1"
                     /translation="MQRELPIPVFLTEDEDSVHERMLSNFQDVSTLEGDFIYDATRPT
                     AEQIAELKQLGLQNNLKIAFPQTSYGTYLEWLGECKGVFKNQPTKATGVITFTGMQGT
                     IITKGTIVTTIATDEKQSIEFELLETKTIGENETVDIKAECRVAGIIGNVSKGSVAVL
                     LGSINGIKSVTNKEDFKGGTDIEDEEHFRERVLVAEQEDKLSGASSDYIRWAKEVDGV
                     GYAYVVPEWNGAGTVKVLILDKNRKAATQELIDKVQEYIYPLNISEGENRDGKAPIGA
                     LVTVVTPDTLLINVKASFIFSNGFSEETVLNNLKTKIDKYLDKIDLGGTVSYNAIQAI
                     VGSMMLTDEGIEDFSNLTINDVKENIKLQDQVVGIGEIVNEVVG"
     gene            complement(80589..81047)
                     /locus_tag="KRH23_000903"
     CDS             complement(80589..81047)
                     /locus_tag="KRH23_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2634 domain-containing protein"
                     /protein_id="HHS5224193.1"
                     /translation="MPNLFPINEKFETVELKNNDENELDLKGSFLFDFEKGEFVKNAD
                     GTLKKCDKVQAYKQWCQKAILTPRHKRSAYSSVYGSEIKELIASNLSQNAKELEITRL
                     IKETLLVHPYTKEVGEFSFNWLENSRLVEYEFNVLTIDDENIVIDGNIKR"
     gene            complement(81025..81387)
                     /locus_tag="KRH23_000904"
     CDS             complement(81025..81387)
                     /locus_tag="KRH23_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224194.1"
                     /translation="MTDARFNGIARILKENMNKSVANSTFGMGCELAEITTNGLKVNG
                     YKDEIQDYLVLESLILKEDYFTFSDEALSGEYRHKHKIETTKELKPLAIGDKVLVAVM
                     GAEFAVIGRVVNAKPISN"
     gene            complement(81380..82342)
                     /locus_tag="KRH23_000905"
     CDS             complement(81380..82342)
                     /locus_tag="KRH23_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdQ/YqbQ family protein"
                     /protein_id="HHS5224195.1"
                     /translation="MKIILNGKYDIANFNEGITLSEAIDGVAYKMDVSLVEPKQLQDI
                     WIKKGDKIVLIDIAYESKKEETIFDGVIWETRRSEKSKKLTLSCRERTVYMEESEEQY
                     SFKENTATQRIEYYCKQWNIPYYNLANTSVKLAKVIHKTNILDMIKKDLKETASKGGD
                     LFRVRMDNKLKLFKLGTNANVYKLDSILEDANFTSSFNDAVTSVKVLGKSKDENTKAP
                     IIGTYKKDSDKYGTLQKIKQDEKIKNTKEAKKAAEAMFNSGEETISVDCAVDINRIRA
                     GDKVSLKSKEYYVIDVTHTLDSRLKMKLNIGTLEYIRRKFYNND"
     gene            complement(82339..83010)
                     /locus_tag="KRH23_000906"
     CDS             complement(82339..83010)
                     /locus_tag="KRH23_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HHS5224196.1"
                     /translation="MVIDIYLKNEKEKIDFHFPVNPFDSLSIKKEKRFETVDIVNLGE
                     FDIKKEGEKIREISFKTFLPNLYDASYCRYSELKNPIEVVAMLEKWVDQAEPLRLIVT
                     GFGYNGLVTISNFSNTQTAGREEDRDIEITFRTYRELKIETLKKETKSNTKTDLKDNR
                     PNNKTTPKIYTVKSSDTLYKIAKNLLGKGSRWPEIYNIPENKKVIGKNPNVIKKGQKL
                     VIPSK"
     gene            complement(83080..83874)
                     /locus_tag="KRH23_000907"
     CDS             complement(83080..83874)
                     /locus_tag="KRH23_000907"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224197.1"
                     /translation="MWGRFKNMSIILKVLVLVCAIAIFPITLLAFSIEFVVKSFKRNE
                     RFKVVFGVFLVFITFSFVCIWYLLEDNITTSNSSNKKQEEHLKEEPGKNLATREAEEE
                     TNKKKEQEKQKNEGTEAEKKERDKTEKKEKVDKKYQEKNKEKAETKKQTLTSEELKKK
                     VDSIIPAEYKGNYYTNDVLDTDGSYVLSLQVQNASFDNESSCKAFTKDLINKLKEFRI
                     DSAEVYFVGSSGQTTYQINIDDFLKVQDNIKSVDNMEFFSFKDFKN"
     gene            complement(83954..88282)
                     /locus_tag="KRH23_000908"
     CDS             complement(83954..88282)
                     /locus_tag="KRH23_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HHS5224198.1"
                     /translation="MREIAKKEMYHIDVVIDVTGDEQTKNKLSAMERYTKQTEKRMRA
                     LNRIKANPVIQAQDKTSSVVNRISNNLKRVGRTISTTINAKDRASSVVNRVKNKVNSL
                     LTSRQREVLLKARDKASQVVDKVKAKVQNLTAATIISLNMKADPALRVISQTRSKLGE
                     LKNNTIINIKAKGEEALNTISRTKSKLQEFSNRTYQAIVKLKDEASPTLSGLDGKISS
                     FISSTISKFTQLAVTATALIGGVGVGSAIKGFADFEQAMKNAQAVSSANSKEMAEMTA
                     MAREMGRTTSFTAKDAGNAMYFMGMAGWKSKEMIAGLPGILNLAATGQTDLALTADIV
                     TDGLTALGLTAKDTGMFVDVMAATVTNSNTDIERMGETFKYMGSVGGALGVSMKDLSL
                     ATGLMASASVKGSMAGTALRGGLVRLIKPPAEAQKAMNKYGIEIKKTKDGNLDLASTI
                     VDLREKLGGLEGVQKSAAISSIFGRTAMAGWAAVVNASEKDFKKLTTAINESEGEAKR
                     IADMKLDTLSGQFEILKSAIDDVRISVGQRLGPMTRSFVEQLTKDMPKIGDAIVSFVS
                     DFINDFDKIKSIMQNVISVISGIVSAFIAFKALKFISFLIPILSDIGFAIAAFAGGAA
                     TLGEALLFALGGPVGAVIAGVVLLATAFTLAYQKSDAFRKIVKNVGKSIKNFLQEAII
                     AISPFVNVFGNKLKELGKAVIPLLKVFGDFASTLMSKIGPIILFLSSNVLAGFILTFV
                     AAVEAVKSAVVAITGVLQGLTSIIKGVFDIVGGIISGDGKQIINGLKSVFEGGIKIVS
                     SVWKGLVDIVTSPIQAVVDVLDEKFGKKVEGIKKKWNELKDFLKNPTKAAPKVQPVNL
                     SGEKASNELQASSNGAKAYISSLGQKIGEGIGKIKDKFGELKISATEVFNNIVSFVGG
                     KATELKDKLLEGIKPAIDTFKQSLSNLKEVFGDSLDSIKEAFGGLKTVFDENIKTPFE
                     NLKQKVLETKESLKPVFDNLKSSFAELGKALEPIKEAFSGIKDFFSNLFKPIKDDGAT
                     KTTKTNMDELKQSTQRVGTSFKELGNAFNQLKEAAKPFIDYLKQIKDSLTSTLGDIGG
                     GLLKGVATSIVLVITSVINAIASIINAVAGAIKGVIDIIKGIFEIIGGIISGDGEKIK
                     QGFSDVFKGIGEVVKSLWEGIKGVLGAPLKAVVNFIDNGFSEKVGQVKQWWSDLKTNV
                     GQKISGFVSFVSNGFQQKVQQVGMWWQGLKVNLSGKISGFVSLVENGFKSKVDSIKSA
                     WDSLRKKLSQKITGFVSIVKTGISNVLDRFADGGVASKPSICGEAGPEMVIPLSNSKR
                     SRALSLYEQAGQMLGTKASNNVIPISQKLGTSFNSASSIQNSNSSIINNVRQFPTKQE
                     EFNNTENRIYQEAQPQNIISSGSNAINVGGISINIQGSNNKEEMIQEILSQVESGLRE
                     ALEDIG"
     gene            complement(88463..88936)
                     /locus_tag="KRH23_000909"
     CDS             complement(88463..88936)
                     /locus_tag="KRH23_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail assembly chaperone"
                     /protein_id="HHS5224199.1"
                     /translation="MANLDKEFLNEGIEEERELTKEEIAKQQEDNIIMKLTEDAILPE
                     KTIFVKRLDIPLTLRALTEKEISALQKKYTKVTKVRGRRESKLMEDEFNIALIEKATI
                     VPNFCDARLLNSMNVSSGVEFIRRKFLAGEIALISDEVLELSGFYEELSDDDIKN"
     gene            complement(89015..89437)
                     /locus_tag="KRH23_000910"
     CDS             complement(89015..89437)
                     /locus_tag="KRH23_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tube protein"
                     /protein_id="HHS5224200.1"
                     /translation="MGKYDENIIDAANVADGSNAKIIVDGKEEGYGTEFTAEVENDKK
                     TFRVIGCKWELNKASTQKGTFSLTVLKTTSEWIERGFDKFELISEIENPGLVGYERIR
                     YKNCMVDKIQLASIKADENIEIQIDGTFEGYELVDKIA"
     gene            complement(89453..90874)
                     /locus_tag="KRH23_000911"
     CDS             complement(89453..90874)
                     /locus_tag="KRH23_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail sheath subtilisin-like
                     domain-containing protein"
                     /protein_id="HHS5224201.1"
                     /translation="MATGTWNEKEKKEIPGFYNRFKTQAEKSANTGLKGRLAIPVKAN
                     WGEVGKVVTIKNDLRQLKTLFGDDMNYSAYKLGKLALLGNVKELLLYRLVDGKQKKGT
                     LTLKDTTENSAKDVIKLETKYPTARNFNVTIKSNLVDSDKKDFIFFENTKQLFSSSIK
                     GTIDEIVLEINSNLDNEYVIATKVADSDTILANVVNQALEGGNDGCTSITNESYLKAL
                     EEFERYSFDSFVLDGVAEEALQETTKAWVAKNKELGKDILLFLGGKAEDNIKQINDKS
                     KSFNDENIVNVGSSAYYEGIKYTPSEVAVYIAALSVSKGITGSICNAKTIFEEVEPRL
                     SQSEVKECLKSGTLILDFDDGDVIIVDDVNTFKKYVDDKNEAIGYISNIMFINTINKD
                     TSLKRKEFVGKIFNDSTGQTTVICALKKYFEELMGQGIISEFNVDIDTELQATAKADE
                     FYWKWDAVKVDVMKKIFGTGYLG"
     gene            complement(90876..91079)
                     /locus_tag="KRH23_000912"
     CDS             complement(90876..91079)
                     /locus_tag="KRH23_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224202.1"
                     /translation="MAETINKKTNVSKQEEKYLKNDFLKNSEALGYEKMVVAGALFNC
                     KKEELTKSEFEKLIKDFLEREVK"
     gene            complement(91092..91913)
                     /locus_tag="KRH23_000913"
     CDS             complement(91092..91913)
                     /locus_tag="KRH23_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224203.1"
                     /translation="MRAGIRKALIDNIKELKGCYEPNVPNKDTKKPYMVVVQGQDNDN
                     GETIGFERSIEIWIYEGRTTFKKLDKLTKQVVEVLDMNTIVDESENEAFTCIYKGTSE
                     NDIVVEEWDAIARGIRFSVIALEDKEDTTNDRWVEALSKYTKDLLEIESYKENWKKNF
                     IAPCALWRTTNVENKRINYHLIEITKTMKCHVVSKNKDEIVKFLEALETSLIIDKRVR
                     LREDKNMYLTLVSVVEDRESDMFTTGQLTVVFKMIGKIKREGPIMDKIYSNGNLK"
     gene            complement(91931..92107)
                     /locus_tag="KRH23_000914"
     CDS             complement(91931..92107)
                     /locus_tag="KRH23_000914"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224204.1"
                     /translation="MKYTLANIRPLNNFLDFNLESFEILTKKMPIDILKPKVELISLD
                     YGEVKLIKKYTDCI"
     gene            complement(92110..92556)
                     /locus_tag="KRH23_000915"
     CDS             complement(92110..92556)
                     /locus_tag="KRH23_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224205.1"
                     /translation="MGINVHLKGLIKMSAFTNAINDINRKKAGMFVLCMSASAMLEGE
                     AKANASWTDRTSHARQSLNAKTLGGGNNFIIRLSHGAEYGGILEEGSKPHVITPKSAQ
                     ALYWRGASHPVKSVQHPGTKAMPIIKPTIDKNIGKIGNMIFRYWSD"
     gene            complement(92522..92899)
                     /locus_tag="KRH23_000916"
     CDS             complement(92522..92899)
                     /locus_tag="KRH23_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224206.1"
                     /translation="MINIDRRRKDIIRTINMNPTNITITNIKKTEIDGAFEETETEIK
                     CVVRIFNEKTAEKQISSEKQGTFSSIRTYGMLVSDDVVLDVNSRDSLEFECIYGRMKI
                     VNVYPQIVKGELCGYQCSLERID"
     gene            complement(92896..93234)
                     /locus_tag="KRH23_000917"
     CDS             complement(92896..93234)
                     /locus_tag="KRH23_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224207.1"
                     /translation="MTPTSNLIEKLRLLLNDKDKKSFTDEELNLFLEEADCIYCAASQ
                     GWVLKSLQYENTVGEMYEYKVGQETYKSSSIKDLVSVAYQNAEKFKDMCTNKKEKGSF
                     MLGISTEFEI"
     gene            complement(93274..94311)
                     /locus_tag="KRH23_000918"
     CDS             complement(93274..94311)
                     /locus_tag="KRH23_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224208.1"
                     /translation="MAFKVISQENLLEQKRKETLQEDIPFIVNGEMEYVTKKISNGEM
                     ETLELNKPLGEMMTFSSTSNLKELLRKVVLDVELGREQVQLLYKPIYDSIADSNLPQV
                     MDAKWALQGNCVFLEHIEGEEIKFGTINAENGPVARIQTYATGFEYTKEMKDFNQTFS
                     VEILNKSIGESYNALLNHIHLSPIINFNYKASNKTAFKGETNDPIWLGIWRTLTQAQK
                     DTVIAKRQGNILMASSADQIEIEMALNGGHLLNGSMYPSIKNISTVIYYDGWEVTVGK
                     KTYSYKGVTPGKGYLIRPKRGFKELIKRDLTTEVGNADLSKLVENQIVGHCYRGAFAA
                     VEENVQEISFR"
     gene            complement(94330..94713)
                     /locus_tag="KRH23_000919"
     CDS             complement(94330..94713)
                     /locus_tag="KRH23_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2190 family protein"
                     /protein_id="HHS5224209.1"
                     /translation="MAFKGQPTPSTITQITRAKISDGKSVRVILSEGESTKTQQFYLI
                     NGFFGVAMQDGEKGDEVTLQIEQAEYETDNIVTSEAFEAGKLIYWDNTAKKFTTTSAS
                     NRLVGRVTDGKDSNNVIWFILLPQQ"
     gene            complement(94729..96063)
                     /locus_tag="KRH23_000920"
     CDS             complement(94729..96063)
                     /locus_tag="KRH23_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224210.1"
                     /translation="MNVITGEMDSMNALISSIKPSDIPLAKDIDIEALKSIDDDPLEV
                     VVEIPATKSKRGWNYTAKSLKDIVDYTNENTLNGFLGHQKAENISTEFALPVTHWIGA
                     EMKGDKAYFRGLIDADATNLKRWIRTKRIKEVSIFGYPKLKKSAKGEMNVIGYEPLSI
                     DWTPLHRPGMPTSIVGMEMSPNGEQLDGTFEALRIDLREALKAKFSINDNNSYLYIQN
                     IRYDNNTVIYELEQNGLCKLYSIPFTIVENKINLGEEIEVIKKISYEAKGEMKGEENK
                     LEGKELIKNVKGLLQTGEISYSEVIQGIGLTKEIVTGEMEDVKSSLKAEKELREVKKV
                     LGIVGEMDTVEVAKKASKALENEKKEAWNCIVNKVIKDKVSGEIAQTLVKKMLNVEEG
                     SSEEVITGEIENILNDEFVKNTMSNMYKDNPTTTGLLNSSNNGSLTTKKNRI"
     gene            complement(96083..97090)
                     /locus_tag="KRH23_000921"
     CDS             complement(96083..97090)
                     /locus_tag="KRH23_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224211.1"
                     /translation="MDKSTSELITVAGEYKKWALEARKKFIDLRLKQDDEIRTMYINI
                     TRNITKEIRKGNLSDFNKVRLKQILKQLTQEIKILNEQLVFNFDEYLNKNVETATSYS
                     KNILINAVETAQITKVTKTMIQKAFYDINIRTVEAYYTRVKDGLFLSDRIWSKCKKYR
                     EDMKVILQTAVTEGQDCVKTAKMLDKYVLKGKKTLVDEYPNMIKRIGNRVPQNISYEA
                     LRLARTEMTSAYGDGVLASAMINPATIGIQFMLSMAHPHTDICDEICGEDNFGLGKGV
                     YPINEAPVYPFHPHCLCIMLTVVQPLDILVGRLKNWIKNPMNDVPLEMWYQEVYGNLN
                     F"
     gene            complement(97083..98585)
                     /locus_tag="KRH23_000922"
     CDS             complement(97083..98585)
                     /locus_tag="KRH23_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HHS5224212.1"
                     /translation="MGIISYVKKLFKRPAGEIMRMSSGNIGVYKLDDSRVDYELAREL
                     YQNKNAKYKLGSSFVRPIVNSTTGFMGVPHFQIEDEEAQYILDEFVLDNTSKMLKTHT
                     DSLKQGDCYIWITREERENPLYPDKKVRLIYNFISPEEVKEIILDPTTKEPIAYILES
                     QNEWTDLGENKRKAKVKQIITAESRFVEVEGDKIEGLEEGETPNVWGFIPIIHFKNEA
                     DETLKYGQSDIEPIEPLLKAYHDVMLHALKGSKMHSTPKLKLKLTDVASFLAHNFGVE
                     DPVKFAKEGGKINLDGHEILFLNKDEEAEFVEVKSAIGDAKELLKLLFYCIVDVSETP
                     EFIFGVHTPSALASVKEQMPIMVNKIRRKREQFTNSWQLLARMVLIMSSNSSGMKYSS
                     YDVTIGWDEVNPRDDKELAETLEKVCSALDKALEGGFISEESTVNFLAQYIDTMSNYI
                     SDDPEIVGEREKIIKTKMLKYRLDDSQGLNDESNEIEKEINKIKDNNGNG"
     gene            complement(98576..99985)
                     /locus_tag="KRH23_000923"
     CDS             complement(98576..99985)
                     /locus_tag="KRH23_000923"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HHS5224213.1"
                     /translation="MDKALLTLLDCYWDNPVWFAEDMLNFKADKWQSDVLMALAQTPK
                     VSIRSGQGVGKTGLESIATVWYLSTRPFPKVVATAPTRQQLYDVLWAEIAKWLSNSKV
                     EKLLEWTKTKVYMKGFEERWWATARTAVKPENMQGFHEDYMLFVVDEASGVADPIMEA
                     ILGTLSGAENKLLLCGNPTRTSGTFYDSHNRDRDLYKTFKVSSLDSPRTSKDNIEMLK
                     RKYHEGSDPWRVRVLGEFPKGESDSLISLEAVETSTIREVNISNDYILNIGADIARYG
                     DDETIIAPRIGGKVFDLLTYSKKDTMETVGNILRAVDKFKNMYHQINRVKIKTDDDGL
                     GAGVTDRLKEVIRHERLKYEVIPIQNGSSAIEKDKYYNKASEMWDNMREELDANLSSF
                     IQNKEAIIQLPNDDKLIKQLSNRKYTVDSKGKIQIESKKEMKKRIGESPDRADAVIYS
                     FAENNNTDLSLLKGGSVWG"
BASE COUNT        31136 a        18170 c        11370 g        39425 t
ORIGIN      
        1 ttaaattagt ttattatact tctttagatt aattttctat acttcctaaa ttagtttact
       61 atacttcttt agattagctt tctatacttc ctaaattagt ttattacact tctttagatt
      121 aattttctac acttcctaaa ttaatttatt atatttttta aattaatttt ctatacttct
      181 taaatattgt cttatacctc tgcaatctta ttatggttac tcatcaaatt attttgcttt
      241 atagtcaatg atttcatttc atgaactgca aagtatatac ataccattgc cgctgctgca
      301 tctgctattg gtcctgcaaa cattactcca tcaattccca taaacattgg taaaattact
      361 atcaatggaa ttaaaaataa aatttgacga gtcaaagaag taaaaagtcc caacactgat
      421 ttcccaattg atgtaaagaa agttgatgat actatttgaa caccatttat aaatgttaag
      481 aacaagaaag ttctaaaata atgttctgca aatataaaat aagtctcatt tccgttacca
      541 aatatagacg taatttgtct tgggaataat tggaaacata agaatgcaat aacagatata
      601 atagttgcac ttcccactgc aaacttatat gcttctttta cacgattata cttttcagcc
      661 ccataattat accctataat tggttgcata ccttgtgata taccaataat tatagatata
      721 aaaatcatat ttactttaat aatgataccg acacaagcaa gtggaatctc acttccataa
      781 actgacctag ccccataata tgccaatgta ttattcataa ctatctgtgt tacagtcatt
      841 gctaattgat taaaacatga gcttgaacct agcgcaaata tatgtttata aattatacta
      901 tctaatttaa aacttttctt atgtaattta atatgttgaa aattctttat ataatgaaca
      961 cttattccaa aagatataag ttgcccaata acagttgcta aagcagaccc agcaattccc
     1021 atattaaaaa caaaaatgaa taatggattc aaaattgtat taataactgc tcctattaac
     1081 atacaaaaca tagaagcttt cggtctccca tctgcaagta tcaacttact cattccagtg
     1141 gacattataa gaaatggtaa tccaattgat gtaatttttg tatatgtgtg tgcataaggt
     1201 agtatttctg atgtagagcc aaagaatttt aatagtggtg ttaaaaatat tgatactact
     1261 ataaataaac ttattccaaa aacagccatc aagcatatag aatttcctgc tgcttttgta
     1321 gctttttctg aatttttagc acctaattcc aatgaacact tagacgctcc tccaattcct
     1381 aacaataatg caattgcagt acatattgtt gttagtggaa aagtgacatt tgtagcagca
     1441 ttacccaata caccaacacc ttgcccaata aatatttggt caacaatgtt atataaagca
     1501 cttactaaca ttgctataat actaggaatt gcgtacttag ttaataactt tgaaaccttt
     1561 tcatattcca atggctcctt atatttttct tccattttcc ttcgcctcca attttgcttc
     1621 ttcattcata tcaatagcca aaaatgcaac tttctttaac attgacataa acaactcttg
     1681 ctcttctttc tcaaatgaac tcaacaactc ctcaacatac ccatttgtta tttttagtat
     1741 ttcatcataa cattctaaag atttttctgt aggatataaa tgccatgttc ttttatcctt
     1801 tacacctggt tctcttgtta taaagccttc tttttctaaa tttgccaaag ctcttgttat
     1861 attactagga ttcacaagaa ttttctcaaa tatagtgtcc tgtgtaatac ctggattatt
     1921 acatatgtgt aatacataaa aatattggct attattgatt ccaatatccg ccaatttcct
     1981 gtcaatataa tttgtattgt atctatttat aatggaaacc cattttaata gctctctcat
     2041 attctctcct ttaatattta ttgtccttat ttttttgcgt tcgcaataat ctatttgctc
     2101 atgcaattat tttactgcta attttatact ttgtcaatag cacacaagtt tatatttaaa
     2161 ccataaagtt actataaatt ttatatatta gactcttact ttgatttaac tatttttaaa
     2221 tcttcattga tatttaatta ccttttatat taattttttt gcatatttat caataactcc
     2281 taattctttt tagcttattt taaaaagcat cttgacgtaa gatttattat ctgtaataat
     2341 aaatatatcg aatcgatata tatctaattg ataccaggag gtaatatgtt agaatacatt
     2401 attttaggat ttttaatgga aaaagaatta agtggatacg acttaaaaca aataatgtca
     2461 gaaagtacct cgtacttttt tgacgccagc tttggaagta tctatcctgc acttaaaaga
     2521 ttagaaacaa aaggatatat acactatcac gaagttatag atggtagcaa attaaaaaaa
     2581 ctatattcca taactaatac tggtaaagaa gtatttcttg aatggttaaa gaaacctata
     2641 aatttttcta aaacaaagca agaccacctt gttaatatat tcttttacaa gtatctaccc
     2701 aaagaaataa ttgaaacaaa cttaaaaatg ttaataactg aagtagaatt acttctaaat
     2761 aaattaagta aacaaaaaaa tgatgcagaa gaaaatcatt gtgttgacca atatacatat
     2821 atgtatgcaa caatgattta tggagttgac tattataatt ttgttattaa ttggtgtaaa
     2881 gatttactga aaaatctata agatataatt tttagaagta aacatacata ataaaaggag
     2941 atggacttta tgaggctttt aatacatgat ttaactgaca aagaattaga aaagttatta
     3001 cccaaacttg atgacaatat aaaaatactt ccaaacacaa aagaaatcca caaatgtatt
     3061 ggttgttttg gttgctggat taaaactcct tctgaatgtg ttgtaaaaga ttattacagc
     3121 aacatgggta aacttataaa tgactctgat ggaattatta taataagcag atgctgttac
     3181 ggagggttta gcccttttgt caaaaacgta cttgataaaa gcattaatta tattcttcca
     3241 tactttgtaa taaaagataa tatgatgcgt cataaaagca gatatgataa acagataaat
     3301 ttaaaagcta tattctatgg agattgtatt acagaagctg aaaaagaaac tgctacgaaa
     3361 ttagtaaatg gaaatgctat aaatttcaat ataaaagaac actctgtttg tttctatgaa
     3421 aatatacaag atataagagg tgaatccata tgaatatagt aatgataaat ggtagtccaa
     3481 aagtaaataa aaataattca cagtattttt tatctgaatt aaaacaactt attcaaaatg
     3541 ataataaagt ttttacattt aaagtagata gcacatctaa gtatcctgac gctcttaatg
     3601 ccatacttaa ttgtgataga ttaataatcg catctcctct ttatgtagat ggtattccat
     3661 ctcatttact tcatttttta gagaaatgtg aaaaattttt aaaaacacaa aataaaaaac
     3721 ctattccagt gtatgcaata gttaactgtg gattcaatga aggtgaacat aatcatttgg
     3781 caattcaaat gatagagcat tggtgtaaaa aaatcaactt tacatgggtt caaggtattg
     3841 gaattggagc tggggagatg tttggttcac tagaatccgt acctttgggt aaaggaccta
     3901 aaaaagattt aggaattgca ttaaaagaac tttcaaaaaa tatacttagt gataatatac
     3961 atatagatga ttccaacaaa agtactattt ttatttcacc taacttccct agattcctat
     4021 ataaacttat ggggaatcat caatggaata ctcaggctaa atcaaatgga ttgactaaaa
     4081 gtgatatact aaagaaataa aattttactt caacaaatac taaaaaccgt caagcacgaa
     4141 taaactattc atcttgacgg ttttttatgt tatttatatt cactagacat gggataattc
     4201 actacaacat tgattgtcta gtctaatatt tatcttattc tttttgtaaa atccaagttg
     4261 ctccaacaag gtcctgctgt aaatcagtat attcattttt ttggctaata acatattgtt
     4321 caaatatatc tttttgagaa ggatattttt taattagctc atttgcacga gttataatcc
     4381 agttcatttc ctcatcaaca tcattttcaa gttctaaaca tggtatacat tcaattagtt
     4441 tcagacctaa ttctttgaac aatatacacc actcattgta agtgggatac accctctcaa
     4501 aattaagctg ttcatttgta gatttatcta ctacatatgc atcatcaatt aaaatgaacc
     4561 ccttactttt tattgtaggt aatagcttac ttatagtttc tttataatta cctaaaatat
     4621 cccctacagc tccaaaaatc acacaatcat aatcgtgctc aatttttaca gaactattag
     4681 catcattcat ttcaaaatta cacaaagcat caaccttata ttcaatagcc tttcttctag
     4741 cataatcaat aaattcaggt atcaaatcaa tacctttgat atgtatattc aactcttttg
     4801 caagcttcac agatacagca ccttttccac aagctaaatc caaaactttt gtatcctcat
     4861 taaaaggtat atgctttcta aataattgta acatttgttc tggtgaactt cctaattccc
     4921 aaaaatcttg taataaataa ggcaaataag gtaaaatatc agtagtatca gaagttagtg
     4981 actctgccaa tttttctttt acagtatcat tcattttttc aacctccaaa atttaaatta
     5041 ttattcaaaa gtaatattat tttatatact tcttcatagg tactacaaac agtggaaaat
     5101 gcttttgacc tttgtatttt gcaattcatt tcttttcttt atgagctgta ataattgtat
     5161 aactgtgagc gtttactgtt ataatacaat catatacact tatataccag ttttttccct
     5221 ttctattaat aatggcattt ggagattcta ttttagtttt acaccagttc actacatcat
     5281 ttgtctccaa agaaagattt ttcttaattc ttacaacgcc taactctgtt gtatgcaatc
     5341 tatctaggtt tttaagtaat tcgttttcta cattcatttt tattaaaaca ccttatcctt
     5401 tgcaaaatta aatctattat ttagtactat tttatcatag tattgtgtat tttatcataa
     5461 tcttatagta aaactatttc tttcctacag actataaatt atttataaat acatacttct
     5521 gtaaaacttt gcctatataa atccatctac tttatacata ataccttctt ttaaatgatt
     5581 ggaacccaaa actgaatttc actcaaacca ttctcatcag ttttttctcc atattttaca
     5641 aagtcatata aattattttc attaaactgg caacttgaat tagggaacca ttcttgatag
     5701 atatattcta caacattttg catactatcc tcatttttcc caataaaagt aaaaacaata
     5761 taattacttt tcggtaatac gaatttttcc attccattag gtaatttgcc aaaagtagct
     5821 acttgagcac ctgcaatgta tgtaaatgta ggagtattct caatctcttt aaaattgcta
     5881 taatcactaa ctccaattaa aaaacctaaa tctaccttat tttctatcat ctctttattt
     5941 ttatgcaaat tcctccagca ttttccaata atatgaaatc cttttcttac tttaccagaa
     6001 tagccaacaa tatttatatc tgcacaatta acttttttaa catctaaaac catatctcca
     6061 cgtaattttt ttctattatg aatatcaaat tttaattgta gtggtaaaaa atcttgatgt
     6121 cttctaaaaa aattaggact acgtttaaac atttttttaa accctcttga aaaagagcgt
     6181 tgtgtatcat accccgagat taaagcaatc tcaataattg gtttttctgt aaaaattagc
     6241 attctcgctg cttcagtaag tctacgtctt tgtatataat tatgtacact aaatccgaca
     6301 actgatgtaa acattctatg taaatggtat tttgaatagc ctatctcttt agaaattaca
     6361 tttaaatcta acatctcatc taaaagatgt ttttctatat aatctaaagt tttttcaatg
     6421 gtaatcaaat tgttatccat atagcacccc tcctatttta aagatagcat attattttat
     6481 tttgtttttc acattctttg ctaatatttt gatttatttt atggcacaca aaagacactt
     6541 ctatttgaag tgcctatcta ctctgtatat tgagcttctt atttcaattt attataatct
     6601 tcaacagata caggttccag ccatttattg aaatcacctt cagcagttac cttgtctaca
     6661 gccaactgct aaattccctt ctatacctta atctaacttt tccacttcaa gtatacaact
     6721 tgaagttagc tctaaatcaa tagtttttat cacaacaatt tgattttaaa tttaaattta
     6781 ttcttttaaa ttatcatcat ctattataga ttttcttata ttcaataact ggtctacaaa
     6841 ttggttagca ggagtattta aaatattctc aggagtatca tactgttgaa caactccatg
     6901 atttaatacc aaagtctttg ttcccaaaat caaagcttca taaatatcat gcgtaataaa
     6961 gataatcgta actcctgttt ttttatgaat ttcttttatc tctttttgta attgctttcg
     7021 tgtaatctca tcaactgcac caaaaggttc atccattaat aaaatttctg gagaagaagc
     7081 taaagctctt gcaatcccta cacgttgttg ctgaccacct gacaattctg atgggtaacg
     7141 cactttcata tcatttggca atcccactat ttccatccat ttgtttacag cactttttac
     7201 ttctaattta ttctttttac ttaggagatt tggtacatat gaaatatttt cttcaacagt
     7261 catatgagga aaaagaacac ttccctgtac acaatatcct attcttcttc ttaatttaat
     7321 taagtcctcg tttttgatat ctgtttggtt tatcaaaata tttcctccat ctggcaaaat
     7381 cagaccatta atcattttta agagtgttgt cttaccagaa ccagatgaac caattacagt
     7441 caaaaactct cctttttcta tatctaaatt aagattatct attatagttt tatcattata
     7501 ttgtttttta atatttttaa attgtataat aggtgtcatt atatttcctc caatttataa
     7561 aagacctttc ttattcagaa actcacgagc aacttctcta ggttctaaat tgttgttttc
     7621 tacatcataa ttcattttag ccatttcttt atcagtcaaa atatctccaa ccatcttaaa
     7681 tacctttgat agttctggat tttcctctaa tacttccaaa cgaacaacat ttccacattg
     7741 ataagatggg tagaaatttt tatcatcttt tagaactaca acatctgaaa cactatactg
     7801 accatcagtt gtaaatatag gcattacgtc aatcttacct tcattgatag cttggtattt
     7861 taatccaata tctaaatcaa ctgtatcttt aaagttcagt ccatatgtat tacacaatgg
     7921 agtatatcca tcctctctct cataaaagtc atattcagct ccaaatgtca atttagaaga
     7981 tacatctttt aagtccgtta tattttttaa attgtattta tctgcaactt cttttctaac
     8041 tgctaatgca tagctattag aaaaaccata cataccagtc cattgcattt taagtttagt
     8101 tttgtattcc gactgtagtt tactaaacat actttcagta tataattcat ttttcttaag
     8161 taccatattc cagcctgtac ctgtatactc tggataaatg tcaaattctc cattctccat
     8221 agctggctgg atattagatg ttccccctcc tacaccttgt gtaatttcca cgtttagacc
     8281 tgtgtttttt tcaattaaaa tatccaacat ctcaccaaga atatattgtt cagtcatagg
     8341 tttagtagca atatgaatag tttgagtctt tgaaggatta aataaataag acgtaaagat
     8401 agttactata agaataaggc ttcctagaat ggcaaaaact tttttcctat ttttcttttt
     8461 tctttttcgt tgaaaaaatt tttctaccag ccctaaaata aaatcaaata ttaaagctaa
     8521 tagagcaata agtatacttc cagtaattgt cattattgtg ttatttgtcg tgattcctct
     8581 atatatggct acacctagac ctccagcacc gataaatgaa gcgataccag ctaatgcaat
     8641 tgtcataatc accatatttc taataccaga cataataaca ggtagggcta acggaagttt
     8701 tattttatac aatatctgaa aatctgtact tcccattccc ctagctgctt caagaatatt
     8761 tttatccaca ttagtaattc cagtatatgt atttctaacc attggcaata atgcataaat
     8821 ggtaagtgca ataacagcag tagtatttcc aattccggaa aatggtatca gaaatcctag
     8881 catagaaata gatggaatgg tgtatagaaa attgatagtt cccaatatag gtttagaaga
     8941 attatgaaat tcacttacaa taataccaat tataccaccc aaaacaatcg caattattat
     9001 agaaataata gaaatcatca aatgttctat ggatagcttt ataaaaaaat cacttctttc
     9061 agataataag gttagaatat catttatcat ccatctctct ccttttataa gttttactta
     9121 acaagattta aattttaatg tagttaatct ttattgttta tacatcagca aatcgtcatc
     9181 aaattatttc acaaattata tattaagatt ataatctgaa cctcccatga ctgaagtcac
     9241 aagtgtgtat agccattttt taatcaaact tgcaagtaga cacaaaaaag taactattag
     9301 agactccatc ctcgatattc tccataaaaa taagaaaaaa ggtcagaacc gttaaaatac
     9361 taaaatttaa acaaatttct gacactttat ttaattaaat ttgaatattt ctcacattat
     9421 ttattactgt taagtttaat tatcatttta tatacccatt atatttatta aaatatcatt
     9481 ataattttat tatattttat ttattatact atatattttg ctgttaatga tattttattg
     9541 ttacataatt gttttggaat accttcaaat attactctcc cgccttttgt tcctccttca
     9601 ggtcccagct caataatcca atcagctctt ttaattacat ctatattgtg ttcaattatt
     9661 atgaccgtat ttccattatc tacaatctct tcaattatac ttataaaatt ctcaatatca
     9721 gccatatgaa gacctgttgt tggttcatct aatatataca ctgaactttc cttatttaat
     9781 tcactagcaa gctttaatct ttgacactct cctccagaca aagtatcaag agtttgtcct
     9841 aaagtaaggt atccaatacc cattttttca atacattgta acttcgtttt aatctgtttt
     9901 aaattaaaaa actcaattgc gtctaaaaca gacatttcaa gaacttcaat tatattcttc
     9961 ccttgaaacc tatattctaa aacttctttt ttaaattttt taccttcaca aacattgcag
    10021 gtactcttta tactctccat aaaagcaaga ttcatttcta ctattccaga acccttacag
    10081 ttatcacaag ctccttctga atttgaactg aataaagaag catttacgcc atttgttttt
    10141 gaaaatatgc ttcttatgtt gttcataatt ccactatatg ttgccaaact cgaccttgaa
    10201 tttgctgaaa cagggctttg gtctataagt acagcactag gattttgctt taaaaattca
    10261 tccttaatca acgtactttt acctgctcct gctactccag taactagagt caatacacct
    10321 ttaggtatct taattgatac attttttaaa ttgtttttat tacaattttt aacttctaaa
    10381 tatccactat gttctcttac actttcttta ataggaagaa atttacttaa agcattccct
    10441 gtcaaagtac cacttgtaag tagattttca taactgcctt catacacaac ttctccacca
    10501 tacttacctg cctttggtcc tacatctaca atatggtctg caatcttaat aacatctggg
    10561 tcatgttcaa caactataat tgtattccct ttatcacgca atttttttaa aagattattt
    10621 aatttataca catcttttgg atgaagtcct acacttggtt catcaaaaat atacattaaa
    10681 tcaacaagat tactatttaa atacttaacc atctttatac gctgagattc ccctcctgat
    10741 agagaagatg tctctctatc cagtgttaaa tatccaagac ctatatctat gatactgttt
    10801 aacttttcta ttattccttt aattaaaggt tgtgcttctg gctcatctat acttttaata
    10861 acttcagcca attcatcaat ttgcatacta gttaaatctg ctatattata accattaatt
    10921 aaagacctat atactctttc attaagtctt cttccatcac atataggaca tctatcttct
    10981 ataagaagtt tactcaattt tttcttagta gcttcagata tttctccctc tctacttaag
    11041 tataggcgat taaatttaac cattaatccc tcatatgtca tgttagtttg accagcattt
    11101 tctatcttaa tcttttctgc tttaccatgc aaaaactttt ccaattctac ttctgaataa
    11161 tcacatatcc tcttattaat atcaaaaaat cctgattcag cgaatatatt ccaatgccaa
    11221 gaacccactc caaaccctga aagcaatata gcaccttcat ttaatgattt attcatatca
    11281 agaatttggt tcatattagg aactagcttt tttccaagcc catgacagtg tgggcacata
    11341 ccatcaatat tattaaaaga aaacatatta gcattaccta tatactcact accaaacctt
    11401 gaatataaag ctcttaaaaa ggaatttaca tctgtaatag tacctagggt tgaccttgaa
    11461 tttccaccaa gtctactttg gtctatgata attggtgttg acaaattttc tatacaatca
    11521 gctttaacct ctccatactt aggtaaaaaa cttcttacaa atgtactaaa cctttcattt
    11581 agttggcgtt gtgattcttt tgcaattgtc tcaaatacaa tagatgactt tccagaaccc
    11641 gacacccctg tgaatatggt tatttttctt tttggtattt ttaaggaaat attgttcaaa
    11701 ttgttctctt tgcaaccttt taaaattata aattcattgt tcatatttta cctcctgcat
    11761 tatttttctt taaattattt agagaaaatc gtaataatag ttgttagtta tacataagtg
    11821 aaatactatt ttattagatt actccttttt ttataaacac aggtcaaatt atagcatgta
    11881 gattttatct ggtagtatag tgtagggttt ggatttttat aaaaaataca gttattttat
    11941 ttaagcgtaa ttacatctat tctacctaaa tatcatcatt atatatgagt gttaaattat
    12001 ataaaattct taagttaata atctcaaaat ggtattagtt acataaaaaa agtatcttgc
    12061 ctatgatttt aaaaccataa ataagatact atgttttaca ctgtttcttc tttcacaaat
    12121 aattctatac aattactcaa cttaacttta aaattttaaa cattaaaaac ctctatcttt
    12181 aaatctttaa ataaaactaa atttccaata ccttcaaaac tatagaaaat tccaatcaac
    12241 ttatcaaaca taacttacta cttataagaa attaatcttc acttaataca gacgtaagtt
    12301 cagggtcatt tagaagatgt tcaaaataac tatgtgccga aatatatcct ataccataca
    12361 ttttacgctt tgaatttaca accttatatt cataacaagc actcttaacc ttattgtagt
    12421 catcaaaatc cattgcttta tagatagctc tttcatttct tggtatatac tttacatatt
    12481 ttggcttaac aaaatacaag tcatctttta tcttaccctc acgtttaagt ttctttaaaa
    12541 cttccccatt ctttctatgc attatatggt catcatactt atagtgatgg gctatatggg
    12601 tcacattgcc tttaaactta tgttcaaaat ccaatatagt cttttccatt aattcataat
    12661 gtgtgccttc ctttttatct atatctgcaa gtataatcac attttgaggt ttcactccaa
    12721 gctctctcaa agctgattta aactcgttat ttctaagttc ttccttttgc ttcctagtta
    12781 aatttctaaa ttttgtgtta gctttgaaaa cgttaactcc agaaccatct gatactaata
    12841 ccacatatac attatcaaca ccacactgtt ttatagcatc tacaatggca cttcctcccc
    12901 ataaaacctc atcatcttga tgttgaggat aaaacactgc tgctgattta aattttctac
    12961 tattactctc aggaataggt atttcaagtt ttccgttaaa attctttgca attaaaaata
    13021 tcatcaataa tattaatata cttattccta tgtacttcgt tttactttcc atatttaaaa
    13081 ttttctcctt cttctgaacc tcccatgatt aaagtcacag ggttactact tcatagaatt
    13141 tcgtataatc aactcaaata tcttataaac ctttgtgtaa atcaggtcta aatatacaaa
    13201 ttattttaca atattttatt gtttcataca atctttgaca cgaactataa taaaataaaa
    13261 aagccttcta actgcaacat tgcaaacatt acagccagaa agcttcttaa ttcttaaaat
    13321 ttattaagct taaaaattta ttaaacttat tttttaatat aaatatgtct attattaata
    13381 aattatactt taattactat atcaatacga ctttactata tcactataac attacttata
    13441 tcaatacaac tatttttata gtctacattt cctttaaaat ttcaagcaac tcttcttcac
    13501 tatacatata cttcttatta cagaactggc aaccaacttc tgctttttta tcttcttcta
    13561 ttatttgagc caatgatttt ttaccaattg caaccaaagc agtttttact ctttcttttg
    13621 aacattcaca cataaaccca acttcacagg tatcaagtat tttaggttcc aaaccatcca
    13681 aaacaatatt taatatatcc tctggtgatt ttccttcttt taacatgtta gttatagaag
    13741 gtaatttagc tacattttcc tctaacttag caatagtctc ttcttctgca tctggcatta
    13801 attgaactat aaatcctcca gcaaactcta cttcatcttc ttttgtaaga acacctaaag
    13861 ctactactga tggagtctgc tctgatacag caaaataata agtaaagtct tctgcaattt
    13921 ctccacttac caatggataa gtcccattat atggttctct aagacctaag tcttttataa
    13981 cttttacaac accttctgta cctactgctg ctgctacatt taactttcca tttggatagt
    14041 cttcaacctc tacttgtgga tttcctacat atccttttac cattccctta gagtctgatg
    14101 tggcgataat agttccaatt ggacctccac cttttattat tacagtcaat ttatcactat
    14161 catttttcat cattaatccc attatagatg tggctgttaa tgttcttcca agtgctgctg
    14221 ttgctacttt tgtagtttca tgtaatcttc tagcttcttc tactgtattt ctagtagttg
    14281 cgacaaatgc tctaacttga ccatttcctg atgtcgctct tagtacataa tctctcatta
    14341 atattcctcc atgtcccgtt aattgtctta tttttattat attactacct taattttaat
    14401 ctataaatac ttatctatct taaccttggg caaaacccat tatattttaa ttttactaag
    14461 caatagttat tatattttaa tttttatcta tagaacttta taattattaa aaaataaaag
    14521 tcataaagta tcatcacttt acttttaatc tataaaactg cattttctat atttttatat
    14581 catggttatt tttaataatt atcttatata gtcaagaata tcttattttt tacatacaaa
    14641 gaagattctt tgactttctt cactaggttt gtcaaatgta aaatccccat aatattttat
    14701 atccttaaat ccagattttt caagcatatc aactatctca tcttcagtat atgctctttg
    14761 ttggtgtatc tcttcaaatc tttcaaactt tccacattca tctttaataa agaatgtaag
    14821 ttccatttca attagattct cttcttcatc aaagtaattt tgccacatat acgctatatc
    14881 ttctctattt tctccataca tgttatttcc caatatgttg gctaatttat aaaaagaact
    14941 tatatcaaat atgaatattc catctttctt taataattca tatgtctttg aaaatacatt
    15001 ttccaaatca tcatcataag ttatataatt aaatccatca caagcacaaa gcacacagtc
    15061 caaatcagat atttcaaaat caagctctga tatatcttgt tgaagtaaaa ccaattctac
    15121 tccttctttt tctgcctttt ctcttgctac actaagcatc tcatcagata tatctatgcc
    15181 agctatatcg taattttttt tagtcaatgg aattgtaaga ttacccgtgc cacatgccaa
    15241 ttccaatata ttttttactt ttacaccttc actatctatt atatcttcta tatatttaac
    15301 ccaaccatta taatcaactt cattcataag ttcatcatat acaaacgcaa aatcactata
    15361 ttgactcatc ctttttattc tgctcctcca caatcttttt aagcctcttt ttgcgtgatg
    15421 taagcatacc tccaattctt cctgcttcct tagctgtaag tcctgcccat ccacgttcac
    15481 caactttatc cataagacct agttctgagg ctatctcata tttcattata tcatcatttg
    15541 tcaatatttt agtattcttg ccattagtta tcttcttttc tctttgtact ttttctttca
    15601 aaaaaatcac cccttcttat ttgtattttt gtcaattaaa ataaatttat acaaatatgt
    15661 aaggggtatt tattaataca ctttttttaa atttaggtat ttatgctttt taatctttat
    15721 aacttatctt cctaatctat tgcttctttg tattttaata attttgaata aacattcaat
    15781 gcatttacac atatcttttc atcaaaatta aagtttatat tatgaagacc atttacaaat
    15841 cctttttctt cgtttcttga acccaacata aaaaataatc ctggaacttc tttttgataa
    15901 taagaaaaat cttctgatat cataagtggc tctaactcta caacagtatc acttccaata
    15961 gcctctacaa actcttgata caaatctttg tcatttttaa cagcgatata atcatctata
    16021 atatttatat taaccttaca gttataagcc aattcaaacc ctctagcaag ttctctaact
    16081 ctaagcttca ttttctcata cacttctggg ctgaaacatc tcatagtacc ttccatcttt
    16141 atattttcag ctattatatt tcttctagct cccccttcaa ttctgccaat agtcaacact
    16201 gcattgtcta ttgggcttat atttctagac actatagttt gaagtgagct tacaaagttt
    16261 gaagctatca ctataccatc aataccattt tgtggcatag ctccatgtcc acttttagac
    16321 actatttcta tgtcaatatc tcctatttga gccataaaat agccctctct tgtacctaca
    16381 taaccttctg gtaactctgg atatatatga agaccatata tttcatcaat attgtatttt
    16441 ctaagcactc cttcatctat taaagctttt gctcccccag gaccttcttc tgctggttgg
    16501 aatataaata ctatattatc atttaagtct tctttattat catttaaata ctcaattaat
    16561 ccaagtaata tagtagcatg tccatcatga ccacataaat gttttacccc ttcttcacta
    16621 tgaagaccat ctatgtcagc tctaaaagca atatcttttt taggtctttt accttctatt
    16681 acacctacta tacctgtttc taaataaact tcatactcaa ttcctaattt atcaagataa
    16741 tctcttatat attttgaagt cttatactct tttctcccaa tctctgcaat aggatttaat
    16801 gacttcctat gtttataaag ttgttcttgt aaatatgatg cctctctcat gtaatctcct
    16861 ccaatttcta atttattaaa aaatatttct atatttcttt ataattaaaa tattatatag
    16921 catgttatac taattaaaaa taaaaagcta aattgaatat aaaaatattt tgcattatta
    16981 aataattcac cattaataat aattcccctg tttcataaat caaaacagag gaattattat
    17041 tggaaaattt tatttttagc aagagaagaa atgtttagca agtccaccct tagctgtttc
    17101 tttgtactta tccatcatat ctataccagt ttctttcatt gtttcaacaa cttggtctaa
    17161 ggagacagaa tgtgagccat cagttaataa tgcataatta gctgcatcat aagctctttg
    17221 agctgccatt gcatttcttt ctatacatgg aatttgaaca tatccatata cagggtcaca
    17281 agtcattcct aaatgatgtt caagtgctat ttctgccgca tattcaatat ggtctatagt
    17341 tccacctttt aagtatgcta ctgctgctgc tgccatagaa caagcggccc caacttcacc
    17401 ttgacaccct acctctgctc cagatattga agcgttagtt tttattatat tacctattat
    17461 tccagctaca agtagtgctt caattatttt ttcgtcatca taattataga aatcctgcat
    17521 tgcaaagaat attcctggta ttactccagc agaaccacaa gttggtgctg taactattat
    17581 attaccagaa gcgttttgct ctgaagctgc tagtgcatat gcatatacaa gtgttgagaa
    17641 gctcttatct tttttatatg cattataaaa tgtacttgct cttcttttta ataataactt
    17701 gcctggtatt atttcatctg tacttagtcc atcatcaata gattttctca tagcatcttt
    17761 tatagttttt atataatctt ttatgtcttt tggttcacat tccaacacaa aatctaccaa
    17821 agtcttatta ttttctttgc accattttac tatctcatcc atagtatcta agtgatatat
    17881 actattgctt ttactgtttc tttgaccttc ttctgctata gtccctccac ctacagaata
    17941 tacagtccat tcagctgtta catttttatc tttatctaaa gcttcaaact tcatcccatt
    18001 tgggtgaaaa tcttttataa tatcttcttc ccaaacaatt tcgacttttt taggtgctat
    18061 agttttttca attatatagt cagttaaatg acctttccct gtggctgcca aactaccata
    18121 taatattgct ctaaaacttt ctgcatttgg gttttcattc ttaaatctct ctgctgctct
    18181 ttgtggtccc atagtatgag aacttgaagg tccacttcct attttaaaaa gttcctttaa
    18241 agtatccata ttattcctcc taaatttacg gtattattgc ttattgttag attttacgca
    18301 catatttatt ataacctaaa tatattaatt attagttatt aaattctcat aaaatttatt
    18361 ttttatttcc attttggtat attttattaa attaatatgc atattttgag aataaaacat
    18421 ttatttaaaa tttttctaat attaatataa tataaatatc ttatttaaac agttaagata
    18481 ttaactatac ctattaaaat taattaattt gtactataat tattattgta cttaaaaaat
    18541 taaatttaga taaaaaagga gatttgatta tatgttattt aaaggttctg ctgttgcttt
    18601 agttacccca tttacagagg ataataatgt caactttgaa aaattaggtg aattaatcga
    18661 atatcacatt gagaatggca cagatgcact agttgtttgt ggaacaacag gtgaggcgac
    18721 tactatgagt gaatctgaaa tttttgctgt aataaaatat acagttgaaa aagttaataa
    18781 gagaatacct gttatagcag gtactggttc aaacaatact atgttgtctg ttcatatgag
    18841 tcaagaagct gaaaaattag gggtggatgg tcttttaata ataactcctt actataataa
    18901 gactaatgag aaaggtctta aacttcactt tgaaacaata gcaaatagcg ttaagttgcc
    18961 aattatttta tacaacgtac caggaagaac taaagtgaat ataaagccat ctgttgtggc
    19021 tgaacttgct aaaatagata atatagttgc tgtgaaggaa gcaagtggag acttagctca
    19081 agttgcagaa atagctaaat tagtacctaa agactttgct atatactccg gtaatgatga
    19141 tactatacta ccactattat cattaggtgg aagtggtgtt atctctgtac ttgctaacat
    19201 atgtcctaaa gaaacacatg atttagtaac taaattcttt gaaggtgata ttgaaggctc
    19261 aaaaaaatta caacttgata tggatgcttt aattgctgcc ttatttatag aagtaaatcc
    19321 agttcctgtt aaaactgcca tgaacatttt aggttttaat gttggtgatt taagacttcc
    19381 tctagctgaa atggaagaaa ctaatcttaa tgtgttaaaa caagaattga caaattttgg
    19441 atttaaattt tagcaatatt tatataaata agttgatttt ttcttaaata tgtattatta
    19501 ttagaataat caaattttaa tatcctatta acctagggta gaggtagctg taactaagag
    19561 tatccaatag tagctggcag gtgttaatga ttggaaaaag gatttacagc cgaagaaaat
    19621 atttcttgca ataatatttt ctgggattgc acataacatg tgtaatactg tcacttattt
    19681 ttgtaggtga tgagctacag ggtttacttt gagtgataaa ttagacgtac aaagtatacc
    19741 tttgtacgtt ttttgtatat aattaaagtt gttaatataa tattaaagtt tttggatata
    19801 taaaaatatt aacatatctt acttgtataa ctaaaataaa ataatgtttt aataatttaa
    19861 aattggggtg aatttatatg aaaaaagtaa atgtagcaat agttggtgct actggaatgg
    19921 taggtagaac atttttaaaa gtattagaag aaagaaattt tccaatagaa aatctatttt
    19981 tattctcttc ttctaaatca gctggttcta aagtaatgtt ttgtggtaaa gaatatatag
    20041 tagaagaatt aaaggaaact tcatttactg atagaggcat acaaatagca ttattctctg
    20101 ctggtggaag tattagtgaa aagtatgctc caatagctgc ttcaaatgga atcttagtag
    20161 tagataactc tagtcaatgg agaatgaatc cagatgtgcc tttagtagtt cctgaggtta
    20221 atccagaagc cataaaaaat cataagggta taatagctaa tcctaactgc tctactatac
    20281 aagctatggt tccccttaaa gctcttgatg ataaatacaa aattaagaga gttgtttact
    20341 ctacttacca agctgtatct ggttctggtg ttaaaggtgt tgaagattta gagaaaggaa
    20401 tgaacggtaa tcctactgga ttctaccctc atcaaatctc ttacaactgt cttcctcata
    20461 tagattcatt cactgaaaat ggatacacta aagaagaaat gaaaatggta aatgaaacta
    20521 tgaaaatact tgataactac gatttaaaaa taactgcaac tactgtaaga gttccagtaa
    20581 aaaatggtca tagtgaatct ataaatgttg agtttaacaa tccatttgag ttagatgatt
    20641 tagtaaaaac acttgaagaa gctccaggtg ttgtagtagt tgataatcct gctaaaaacg
    20701 aatatccaac tgctgtagaa tttgatgata gagatgaagt atttgttgga agaataagaa
    20761 gagattttag tgttgataat ggtgtaaatc tttgggttgt tgctgataat ataagaaaag
    20821 gtgctgcaac taacgcaatt caaatagctg aaatggcttt atcatacgat ttagtataat
    20881 atacaaactt gtaaatatat aattttgtaa aatattaata gtaactcaaa aacaagcatt
    20941 agaagtaact gtaatataaa acacaaaaat aaaaaagagg ggattgattt tatatgatat
    21001 ttaaaggttc tgctgttgct ctagttacac catttacaaa ggataacaaa gttgattttg
    21061 acaaattagg tgaattagtt gaataccaaa tagctaatgg tactgatgct atagtatctt
    21121 gtggtactac tggtgaagct aatactatga ctgatgaaga acaacttgct actattaagt
    21181 atgttgttga aaaagttaat aaaagagttc ctgttatagc tggaagtggt tctaatgata
    21241 ctatgcactc agttaactta agtcaagaag ctgaaaaatt aggagtagat gctctattaa
    21301 taataacacc ttattacaat aaagctaata aagctggact taagcgtcat tttgaaacaa
    21361 tagctaacag tgttaaactt ccaattatac tttacaatgt ccctggaaga acttgtgtaa
    21421 atataagtcc tagccttata gttgaacttg ctaaaattga taacatagtt gctgtaaaag
    21481 aagctagtgg agacctagga caggttgcag aaatagctag tttagttcca gatgactttg
    21541 ctatctactc tggtaatgat gatactatac ttcctttatt atctttagga ggtcaaggag
    21601 ttatatcagt acttgctaat gtttgccctc aagaaactca cgatttggta gctaaattct
    21661 ttgaaggaga tattgaaggt tctagaaaat tacaacttgg tatggatgct ctaatcgcag
    21721 ctttatttat agaagtaaat cctataccag ttaagactgc aatgaattta ttgggattca
    21781 atgttggaga tttaagatta cctctagcag aaatggaccc agcaaattta gaagtgttaa
    21841 agaaagaatt agttaacttt ggactaaaag ttaatgcata gtaaagatta atgcatggta
    21901 aaaagtaagt ttggtcaaaa gttagccctt aatcatagga ggaaattatg ttaaaagtta
    21961 tagcaactgg ttatgatgga aaaatgggta agattttagc cgatactata agagaagata
    22021 atgaattaga attggtttgt gttgcagcta gaggtctgga tagctatgaa ggcgacctta
    22081 aaatttatga agatatgagt actatagttg aggaagctga tgtagttata gatttttctc
    22141 atcactctaa tttagataat atcttatctt acgttttaaa gactaaaaca cctttagtaa
    22201 ttgctactac tggatataat gatgacgaaa tgaacaaaat acgtgaagcg gctaaagtta
    22261 ttcctgtatt ccaatcatat aatatgtctc ttggtgtaaa tgtattagta aaattggtta
    22321 aagatgcagc taaattacta gaaggatttg atatagaaat aatagaaaaa catcacaaca
    22381 gaaaagtaga tgccccaagt ggcacagctg ttatgattgc taacgctata aaagaggttt
    22441 tgccaaacgt tgaaaataat tatggtagat atggtcgtag tgcaaaaaga caaccaaatg
    22501 aagttggtat tcatgctata agaggtggaa atattgttgg cgaacatgat gctctatttg
    22561 ctggagacaa tgaggttctt acaataagcc atcaagctca atctcgtggt atctttgcaa
    22621 gtggttctat agctgctgcc aaatacttag ttaagcaaaa accaggattt tataatatgg
    22681 acagcatgtt gggataatag cataaatata ataatacaca atataaatta aacatatgca
    22741 atatagatat aataatacgc aatacaaatc aaacatatgc aatatagata taataatatg
    22801 caatacaaat caaacatata taataaattt atttaatact atgtctatac aataaaaact
    22861 aaataaaata taaataataa gaagtaagta tatactaaaa ttgacaaata agtatataat
    22921 aaaagaaata taatgaaata caaggagaat taacaaatgg taaatttaaa cgatgcttat
    22981 gaaatagcaa ggtatataaa agaagttaaa aagaaaacac ctgttaaggt atatgtaaat
    23041 actaactctt tacacttcca atcaactgat aaatttaagg tatttggaaa taatggttct
    23101 tatatatttg taggtgacta tgaggatata atggaagtat tagataaaca tggaaatgat
    23161 ataacagata ctcatgtaga atatgataga agaaattctg ctattcctct aaaaaatact
    23221 ttaagtgaac atgcaagaat tgagccaggt gcaataataa gagacatggt tactatagaa
    23281 aaaaatgctg ttgtaatgat gggagctgtt ataaatatag gagctgttat tggtgaaggt
    23341 tctatggtag atatgaatgc tgttattgga gctagaggaa ctcttggtaa aaatgttcac
    23401 ttaggtgctg gtgctgttgt tgctggtgtt ttagagccac cttctgctac tcctgttata
    23461 gttgaagatg atgttttaat aggagctaat gcagttattc ttgaaggtgt tagaatcggt
    23521 aaaggtgctg ttgttgcagc tggtgctgtt gtaactactg atgtagaagc tggtgccgtt
    23581 gttgctggtt ctcctgctaa agttataaaa atgaaagatg aaaaaacggc tgacaaaact
    23641 aagcttatgg aagaccttag aaatttagac taattaaata gtactatact attaattaaa
    23701 caataatata ataatttaaa aaattaatta aaaaggtgtc tctgtgtgaa tttaattcac
    23761 cagaggcacc ctctttttta caatattttt atcttttatt tataatcatt ttattttttt
    23821 acaattctct tattcattct tatatcattt ttatttcttg ctgacaagta tttttatttc
    23881 cttcaatttt tcaatatatc aatgtaataa actaattaat ctttctataa tttaataaaa
    23941 tgaactacta aattttctat atatcaataa aataaactat taaacttttt ataatttaat
    24001 aaatagaact gctgtttatc actggttgtg catctttatt gccacaaagc acaactaaca
    24061 gattacttac catagctgct ttacgttctt cgtccaaagt cacaacatta ttttcactta
    24121 aattagtcaa tgccatctct accatactta cagccccctc aacaatcttt ttacgtgctg
    24181 ctattatagc ctctgcttgt tgacgttgta acattgctgc tgcaatctct ggtgcataag
    24241 aaagatgagt aattctcact tcacacactt caattcctgc aatgtcaacc cttgattgta
    24301 attcatcttt taatctatct gctatttcct gactactacc acgaagagat ttttcatctc
    24361 catcttcaga tacatcatat ggataaagtc ttgaaacatt acgaatagta gaatcacact
    24421 gaatagataa gaatgtatta taattatcca cattaaatac tgcctttgtt gcatctataa
    24481 ccttccaaat tacaaccact cctattataa ttggatttcc caataaatca ttgactttct
    24541 gcttttcatt attaagagtc attgttttta aagatacttt tttgcccctt gaattagttg
    24601 atatatctac cttttcatca gatgaagatt tcgatacatt aattcttgat actgctgggt
    24661 ttattgctga acaaaatgga ttcacccaat agtacccttc tttttttata gttccataat
    24721 agttaccaaa caaaactaga actatagctt ctttaggatt aatcattttt agcccaaaaa
    24781 ataggataaa atctactact ataaatacaa gtcccaaaat taacataagt gaacctattc
    24841 cagtaaatcc actatcaagt tttactatcc caaaaaccat gatacctatt gaaactacta
    24901 aaaataataa aatcattatc aaagctgcca ctccattgaa tacttttgcg tctttctctt
    24961 gataagtttt ttcttctttt aacatatcta tcactcccat ctcagtatat taagttaaga
    25021 tatctctaat ttaataataa cacttttaac aattaaattg ttgaatttaa aattaatact
    25081 atatgtttat atatttttta tacatcttta tgcatacatg tatttagtta ttttaatgta
    25141 ttaatattaa tttccaaata aatcatatga tatatgaata tggtatttca aaattaactt
    25201 tttagttcat gggtcactct ttttggtatg aagtcaaata tatttttatc atttaaacaa
    25261 tgaaaaagaa atttatctat attttgaaaa acccacttaa attttttaat gtaagataaa
    25321 ttgtaagctt attatcacta atattatttt atataaatta tattagtgat aaaataaact
    25381 tatagaaata taacaaattt ttattaattt tataggagga atttatgttg aaagttataa
    25441 ttagtggcta taatggaaca atgggaagag ttttagcaga atgtgtaaaa aaagataatg
    25501 aattagagtt ggtttgtggt gtagctaggt ctgctgatga aaaaggtcat catagtgata
    25561 caaagcttta caaaacaatg actgatgtaa ctgaaaaaac tgatgtaatt atagactttt
    25621 cacatcatga gactttagag ccaatattgt catatgctct aaaaaataat acacctgtag
    25681 tattagctac tactggatat gacgaaaatg acttaaataa aatagaagaa gcatcaaaaa
    25741 acattcctat attattatca tcaaatacat ctcttggagt aaatatatta ataaaattag
    25801 ttaaggatgc ttcaaagatg ttagaaggtt ttgatattga aatcatagaa aaacatcaca
    25861 atagaaaaga agatgcccct agtggaactg ctactatgat agctaatgca attagagaag
    25921 tcttgcctga aagtgaaaat acacatggta gatatggtag agattgtaaa agaaaaccaa
    25981 atgaaattgg aatacactct ataagaggtg gcaatataat cagcgaccat gatgttatat
    26041 ttgcaggtga taatgaagtt cttacattaa gccatcattc tcaatctgat gaagtatttg
    26101 caaacggttc tatagttgca gctaaatttt taattggtaa gcaatctggg ctttataaaa
    26161 tgtcagatat attaggataa gttttgtaca taataaatct caatctattt aggtattcat
    26221 attcatcaat ttgaatatct aattgattga gatttctatt ctaaaagttt ataaatttta
    26281 tgcttacttt ttaaatataa tcatttttct taaagattat cttatttatt ggtatatgga
    26341 attatattgt ttattatttt ataatctctt catcatataa acctattaaa tattacccta
    26401 tttattggta tatggaatca tattgtttat tattttataa tcttttcatc atataaacta
    26461 ttgtattcta taaactgata catatccagc tgcagaagta cctgtcgtgc ctgaaccaaa
    26521 tgtaaaactt aaagtaacag ctgctgctct agcatcaact aaaaagctta aacttacact
    26581 tacatctgat gaagtaagtg tatttactgc ttttgcaata aagttatttt gagctactcc
    26641 attaaagtta gtagtaattg acataaatcc tgcaagtgaa agtgtggcac gtataccgaa
    26701 agatacattg tatatccctc caactgcaag atttatagta ctacttgttg gaaaagttat
    26761 attagttcca tttataaatg atgaattaaa tgtcactaat gtattattta ctaaacttga
    26821 agaggacact gtaaattgtg cattgtttgt tgctaacact cctgttgctc ctgtcgctcc
    26881 ggttggacct gttgctccat ttgctcctgt tgctccggtc gcccctgttg ctcctgtcgc
    26941 tccatttgct ccagttgcgc ctgttggtcc tatcgctcct gctactccat ttgctcccgt
    27001 tgctcctact gctcctgttg ggcctgttgc tccatttgcc cctgttgctc ctgtcgctcc
    27061 tgtcgctcct gctactccat ttgctccggt tggaccggtt ggacctattg gacctgctac
    27121 tccattcgct cccgttgctc ctactgctcc cgttgggcct gttgctccat ttgcccctgt
    27181 tgctcctgtc actcctgttg gacctactgc tccatctgct cctgttgggc ctgttgctcc
    27241 tactgctcct gttggaccta ttgccccagc tactcctgtt gctcctgtcg ctcctgttgg
    27301 acctaccaaa ccatttgctc ctgttgctcc ggttgggcct gttgggccta ccaaaccatt
    27361 tgctccggtt gctccagttg ggcctgttgg acctgttgga cctaccaaac catctggacc
    27421 tgttgctcct actgctcctg ttggacctac ctctccatct gctccggttg gacctgttgc
    27481 tcctattggg cctgttgccc cagttgttcc tgttgctcca gtcgctccta tacttccggt
    27541 tggacctgtt gctcctgtat ttcctgttgg tcctgtagca cctgttactc catttgctcc
    27601 ggttgctcct gtatttcctg ttggacctgt tattccattt gctccggttg ctccggttgc
    27661 tccggttagt ccggttggac ctgttgctcc agttgctcct gtattccctg ttggacctgt
    27721 tattccattt gctccagtcg ctcctgtatt tcctgttggt cctgtagagc ctgttattcc
    27781 atttgctcca gttgctcctt tgtttcctgt tggacctgtt attccatttg ctccggttgc
    27841 tcccgtattc cctgtcggac ctgttattcc attcgctcca gtcgctcctg tatttcctgt
    27901 tggtcctgta gagcctgttg ttccatttgg tccagtcgct cccatatttc ctgttggacc
    27961 cgttattcca ttcgctccgg ttgctcccgt atttcctgtt ggacctgtta ttccatttgc
    28021 tccggtcgct ccagttgcac ctctaggccc cgtcggtcct gttggaccag tagcacctgt
    28081 tggccctgtt ggacctacat cttgatataa acttggacct gaaatatcac tcatataatt
    28141 aatcctcctt ttttaaagtt agagtattac tctataaata ttgagtatta ctctataaat
    28201 attgagtatt actctatata attatatgaa tcgacaattt cttatgtgat aatgtatcta
    28261 tttgcttata tcaacatata tgctttgatt cttgaatttc attacttttt tgtaaaatct
    28321 tttacaatta ttagtactct tttacaatta ttaatacaat taaaaaactc atttcccatc
    28381 aattatttaa aattttttta ttatgttata aaaaatagat aattaaattg cataaaatta
    28441 atttaatact actttaatta ctttgtaaat aaaaaaacct caacacgatt aataaaaatc
    28501 atattaaggc atccacaaaa ttatataatt gcttatctat cttcatcagt aacattgaat
    28561 atataaggaa catttctata ataatcacca aaatcaaacc catatccaac cacaaactta
    28621 tcttctattt caaatccaca ataatctggc actaaatcga cttttcttct gcttggttta
    28681 tccaaaagaa cacagcattt taaactagca ggatttttag cttttaaatg ttttaacaca
    28741 aaatccatag taagtgcaga atcagtaata tcgtctacaa ccaaaacatc atatcctgct
    28801 atatcagtag tcacatctga aactacttta acccttccag tactttcttc attgtttcca
    28861 taactagatg tagtcataaa attaactcta agtggtaaat ttatatttct aactaagtct
    28921 gcacaaaata taaagctacc ttttaataga gaaactacca taagattttt atctttataa
    28981 tctttttcta taattgctcc taattccctt aatttatctt taattttttc ttctgaatac
    29041 aatacttccc atttttttgt ttctatatcc ataaaaagac ctccaattgt aataatcctt
    29101 cttaatttta taagagattg ctcacttttt caatactctt attcaatatt agtcaatatt
    29161 attgagtttt tatgttcatt caacaattat taacaatgta tcttatattt taagtagttc
    29221 atatatccac actaaattac atactatata ttttagacaa aaaaagaaaa aacttgcact
    29281 aacaagtttt ttctattata cataaattta tacataatca tattttatta gagggtacta
    29341 attaaattta tttatgctat ttttgttata cctcataata caaaacatat tataaagtac
    29401 tagtcaactt tattcatatc attcattaca tttaagatta tctcatctgt tatagacata
    29461 cctttgtcac ttactctacc taagttttgt atactttgct caacacttga accaactata
    29521 ccatttagtg gtggtacaaa acaatcttgc ttagctatta tagcactttg tatagctgca
    29581 gatgctgcag aagataattt taatgcacaa ccagctttcg caccgtcaca tatcattcca
    29641 cttaagtcag ctatcatatt ttctatagct ccttctattt gcttttcagt accattcata
    29701 agccaagaga taccagcagt tgctccagta gaagcagcaa caccacatcc acatacagca
    29761 gataatcttc ctgtatagtt cttaatataa ccagttacta gatgagatat agctaaagct
    29821 tttgctagtc tttcatcaga ttgtgggaat tttttattat aagcaacgat tggaagaatt
    29881 gctgttaatc catgatttcc acttccattt gaactcataa caggcatttt tacccctgcc
    29941 attcttgcat ctgaagctcc agcagttaac atcattgcat aatttataac atcattacct
    30001 aaaagacctt cttctataga ctttttaatt ccatacccga caccaatacc agttttttgt
    30061 tttaatccat attcagccat ctcttcattc atttttactc catctagtaa aaattctata
    30121 tctttaaaat caatttcttc tacatttttt attaattctt gtatagttac tgtatccatt
    30181 aaactttcag ctttttctgc cgcatcattt gaagctgata cttttggttc attgtctaat
    30241 aatacttctc catctttttc taagaacgta aaattatcat gtttagttct tattctcact
    30301 ttagcaatat gattttttcc ttttaacaca acttctataa atactttctc tcttgtatca
    30361 gcaggtgtta ttgatagtgg agtattatcc atataatcct cagctatttt aacttcctct
    30421 tttgttagag tttctaacac acttaatcca ttttcagaat gtccacctac tatacctaga
    30481 gctgctgcaa tttttaatcc taatctttca gtacctggta tacctacgca cataccattt
    30541 ttataaatac taggactaac taacatacga ttttcaacta tttcttctcc taataattcc
    30601 tttgcctttg cacatgctag agctaaggct actggttcag tacaccctac tgctggttta
    30661 acttctgcct ttaacatttc cactaattct tttcttatat ctctcattat atataaacct
    30721 cccaattaag tttagattta gtactcaaat aattaattaa ataatttctt atctatattt
    30781 atagcaaaat acatgccata ttttttatat ctttttatat ttttagtctt atattctata
    30841 accattggta tgactgcctc tatttatgta ttttttttat ttgtatagag tatttatatt
    30901 ctttaaaatg gagaaacata tgacaatttc gcaaaaagac aaaaaaaagt ctcaaaatga
    30961 gattctatat cattttgaga cggctcaaat atattatttt ttaacttata aaaaccattt
    31021 tttaattcat aaaaaaagat tctgcaaaac acttatagta taagtttaaa gctttcttta
    31081 aagttatgaa tttagaaaaa tttaaatttt atatagcttt ttattatatt actatgaaat
    31141 tatattgtat ttttcaattt ttctatataa tgtagctctt gatattccaa gtgctttagc
    31201 tgttaattct ttatcttttt tataatcttt gtacttattt aaagctttta ttatctcaat
    31261 cttctctagt tcatcaagtg gaattatcct atcgctttta acttctaact cttctacaga
    31321 ggtattctta attttttgag gaattacatt cattgtgatt attgaagaag aagacatatt
    31381 cacactatat tcaataatat tctgcaactc tcttatattc cctggccact tatattccat
    31441 catagcatca acaaccctgc tatctatgtc aataacattt ttatctaatt tttttgaata
    31501 ctctttaacc atatgcttga ttataagtgg gatatcttct tttctctctc ttaaacttgg
    31561 taattttata ggtataacat ttaatctata gtataaatct tctctaaaag tgccattttg
    31621 aaccattttt tctaaatctt tatttgtagc agcaataatt cttacatcta ttgaaacatt
    31681 tgatttactt ccaattttat taagttcctt ttcttgtaat actctcaata actttgactg
    31741 taaatgcaaa ctcatatctc ctatttcatc taaaaatata cttcccttat gagctacttc
    31801 aaacattcca agctttccac cttttttagc tccagtaaaa gctccctctt catatccaaa
    31861 taattcactc tctaataaat tgtctggtat agcagcacag tttacagcta taaaaggatt
    31921 atctactcta ttgctatggt tgtgtatggc tcttgcaaat agctccttac ccgttccact
    31981 ttccccagta ataagtactg ttgatgttga tttagaagct attagggctt cctttttaga
    32041 atttcttata gctacacttt ctccaattat gttttccaat tttattctat aatctttatt
    32101 catcttattg tagtttttta tagcatctct cttatctata aaatcaataa catatccctt
    32161 taactcattt tttaatacta ttttattgat gttgtatatt cccttcgaat catatccgta
    32221 tcttttataa aaaaaactac aggatttgtc cttcttaaag ttatttatag aaggtttctt
    32281 tataaaatct aattcgacaa atatgttttt gccagttata ctatctttta tattgaaaag
    32341 ctctttaaat tttgaattat atttatcaat ttttccatcc acatcaatag acacaacagc
    32401 tttgtccata ttgtttaata gtgtctctaa ttttttcttt tctaattcaa gctcataagt
    32461 tttaatttgt gcttttaatt tattagatat taggtctgcc attttgccta aaaagtttat
    32521 aagaccactt ttattatttt ctataatttg tgcttgttct tttgtaaagg ctataaggcc
    32581 tataacacca tgagaatcgc catcacatat aataggacaa cacacctctg caaactctac
    32641 acaagcccca cttttatagc attccctaca tatatcacta ctctttgggt catcaattag
    32701 tattgtaatc tgttctgtaa gtgatttttt aaaagccgta tatttatcta ctttctcacc
    32761 tattttgtct atatatactc ctgtacctgc aatcctaaat aactccttat ttactatagt
    32821 tacatctata ttgagtactg atactatagc ttcagctata ttttgaatat cagattttat
    32881 atattctaaa cctatcataa tcatcattcc ttatttttct ttagcataag tatttgtctt
    32941 atttctttaa gaatcaagta tatcttattt aaagtaaatt ggattgacat caggattaca
    33001 aagagcataa caattattat taactcataa tttatttcca tctaaacatc tccttataac
    33061 aaaagactag gcttaaccta gtcttttata ttatatccat atttatattt taactcattt
    33121 atcttctttt tcccacataa atatatttta atttatttga ctctttaatc ataccatcaa
    33181 agtttaatct tgaaaatata ttaaatactt catgtggata gtgaatcttt gcaacagaac
    33241 cacaaaattt atgtttaaga tagtttaact taacttttaa attctttaaa tttaaatcct
    33301 ctaatataac ctctccattg ccctttaaca ctctttgtat ttcagatgaa gctttttcac
    33361 aatctgtaat aacattaaat tggtcaacta ttattatctt gttgaactga ttatcatcaa
    33421 atggtagaaa ctctaactta cctttaacta cattgcaatt ttcattatac actagagaat
    33481 aacagacatc ttcataatta ctattctcca gtatagttac agaagttcca agacctctca
    33541 atctcttgcc taggtttcct atatgaccaa caagcaatat tttatcacct acattatact
    33601 caattgtatc caaaaaacat tctaattcat cagatgtata tttagcttta accggctgtt
    33661 tatttatctg acataatatg cttttcacaa tgcttcacct cttcatttcc tcaattataa
    33721 attatgtaca gattacatta taataaatgg cgagcaacta ttcaagagat atttcattag
    33781 tattttttta aacaatcttt atacatttta atatgatatt ataccaaatt tattaggatt
    33841 ttattcataa aaatcagtct atttttcatg tttattcatt gttattttca tccaattttt
    33901 ttattttcga tatggatact tcatatgcca tttttttgac cacattattt tcatctattt
    33961 ttttctcata ttctctactt tgaaccctac cccaaagctg tattctatca ccaaccttta
    34021 gattctttgc aaatttagca tttctacccc aaactattga tggtatataa tcagatttat
    34081 tataaggtct gtttatagca actaataaat cggttatttc ccttcctaaa ggtgtcttcc
    34141 tatacacagg ttccttacat acatatccat ctaaaaatat actattaggg tctttatttt
    34201 cctcgtctat gctttttatt tctctgacaa acactgtaag cactaatcta tttttattat
    34261 ttaatgtttt gttatatgat cttaattggc ctacgacatt gactaaattt tgtttatcaa
    34321 ggtcaatatc ttggagaagt ctttctgata cagtcattgg aagtatatca aaagaatcgc
    34381 ttagtctgtt tatttttatt ttcatattat aaaatttttc tccaaatatc tcatggctaa
    34441 attctagctt attgtctaac tcccctctta agtttactac gttattctca tctttaacag
    34501 ctatcatatt ttatccctcc acaattgtta attcttatat ttctggtatc agcttatata
    34561 ataaatatat ttataaggga tgtattttat tacaaatctt tgattgctgt ttaaaagttt
    34621 ttatttagtt ataaatttca tttaatattt cacttttata attataaaat tattatcttt
    34681 ttgtaccaca tatactaatt aaactaccta tttcagtttt gtattaatta taaaaatcct
    34741 attatatagt taataagtca tatataactt aaatttattc actctatata agcaacttca
    34801 acgaattaaa tttattcaaa taattcagat gaatattgag tcattataaa cttatttttc
    34861 ttaattataa gttatattag acttattaca ggttatattt ttattaatct gtattaatat
    34921 atgaacattt attgaactta ttgattataa aatttaaata tttagcttta aattatgctt
    34981 tattctttaa aaatacaacg ttttttacat taaatctact aaatcactat atatattaca
    35041 taattggcat gttaattgct ttatattaat ttagtaaata aaaaactgcc ctaaaatatt
    35101 aattcaatat tttaaagcag tttataatct ttattattag ctgtaatatt taataaacac
    35161 taagtagtct ttaactaagc agtctttttg tttttatttg cagccattat cattgtagca
    35221 gaagtataag ctataactac tattactaat gcttttaata tatccattgg tagagttttt
    35281 actatatatg cagctacgaa aactcctatt aaaccacata tagctattat aactgatgct
    35341 tttttagtat atgcatcttc ttttatgaat ttcatacttg caactggcat taataatgca
    35401 caagaaccca taactattgg gaatgcaact tttgcagaca ttcctaagaa ataaaccatt
    35461 gccatacctg gagcatataa acctatacca gctgtcatta aagctcctag tataaagtta
    35521 cctattacac ctattactaa tttaacacca gtaagaccta attcatttcc tccacctggt
    35581 aacacgttaa tccaaggatg acctaataac attaatattg ctgttaatgc taaagttaca
    35641 cccataacaa gttgtatttt tctctcgtcc atcttagata ttattcctgc acctatatat
    35701 gaaccaactg ctgctgccac aaccatagat actaaagtaa caccatcaac tggtatgatt
    35761 gatgtaaata tgaatgcttc tgtaacaact ggaatagtat gtgctacgtt taatgtacca
    35821 ggcatttttt tatctggtat atttaacttt aaagcctttg acattgctat tgttggagca
    35881 aatgacccta ttcctaatgt atcaaagaag tctgttataa atcctgttac agcaactttt
    35941 ggagtacttt gttcttctag tttcccctct ttgtttgctt tagctacgtc tttaccaaac
    36001 acaactgcaa agattgctgc gaatactaca tataatgcct ttaagattgc taccataatc
    36061 catcctccta tttttttatt ttttcatata ttctgaatct tatagcctaa aagctataga
    36121 atagcaaccg acaagtggct actattctat tttaatttcc taatttattt attacttact
    36181 taagaataaa tccatgttta agtgggtctt cttcatctat tacaaaatga ttaaatccag
    36241 ttatataagc agaaccagtt attttaggta ctacagcatt gaaatctgca actttagttt
    36301 cttcaactat ttcacctttg aataaagttc ctaatatact ttcatatacg aatttttctc
    36361 ctacttttaa ttcaccttta gcatgtaaag tagctaattt agcacttgtt ccagttccac
    36421 atggagatct gtcaacttga ccttgaccaa atataactac atttttgtaa gtagcttctg
    36481 gatgagttgg ctcatcatat atttcaacta agtctacagt ttttatatga gctaaagttg
    36541 gatgttgtat ttctattttc tcatttatta tatctctaag tttcatagct agttcagtta
    36601 atttaccagc attttgaggt tcgattttta aacctaattg acttgcatgt attatagcaa
    36661 agaagcttcc accaaatgat atgtcaaatt taacagttcc aacacctggt aagtcaactt
    36721 caacaccttc tttatataag aaagctggta cgtttaagaa tgatacttct ttagcttttc
    36781 catctacaac tgtaacgtct cctcttatta ttcctgctgg agcttccata actacatgag
    36841 ttacaggctc tactgctgga actacacctg tttctatagc tgctgtcata gctcctattg
    36901 taccatggcc acacatgtta aggtatccgc caccatccat gaagattatt ccaaagtcag
    36961 catctgggca acaaggttga gtcattacag aaccaaacat atcattatgt cctcttggct
    37021 ctaacattat agcagttctt aaataatcta gattttcctc taaatattct tttttctcag
    37081 gcatagaatt tccttttatg ttaggtattc cacctacaac tattctagtt gcttcacctg
    37141 ctgtatgaga gtctatagct tgtatacttc tgctaaattt catatcaaat tcccccttag
    37201 gtttattttg cgtctttacg catttttaat tttaggaaag ccaatgcttt tttaacatca
    37261 acttcatcca tgtgattgtc tccaactact tctgtttcta tgtagcctgt tgtcttttta
    37321 taatcaatta tggtagcttt atccaaatat ggattggtaa ttactaatcc atctgctccc
    37381 ataatagtaa gacctactgt aggtatatct gattttacaa actctgctat agcatttgta
    37441 aaatcaatat gctggtttcc tgccatatct aaagttataa tcactccatc aggtcgcaat
    37501 gattcaatcc atcttccaag tctagttgct aaaaatgttt tccattcatt gtgctctgat
    37561 gtcccaacta caaccactcc taacaagtct atgtcagaat cattatctat caaatctagt
    37621 aacgggtctc taaatatatg aagtgatgtg tttttcattg atgtagaaat tcccacaaaa
    37681 ctcattccct tacttaaatt ttttatccat gttttctcat tttaagtttt aaaaatgcca
    37741 aagctttttt agcatctatt tcatttgtgt tgttttctcc aactacttct gtctcaatac
    37801 cttcttttga tttgttcata tcaactatgg tatccatata ttgattgctt acaacaaact
    37861 tagcttgagt cccattaaat gtaactccaa ctacaggtat atctcttttt cctatttcct
    37921 caaatgtgtt agcgtagtca acatgtgagt ttccccaacc atctgatgaa actatagctc
    37981 catctactct catagcttcc agccaagcgg ccgttctttg tcccacaaag gttttatttt
    38041 catttccatc tggagttcct actactatta ctccaagtaa atctacatcc ttatcacttt
    38101 caactatgtc taaaagtggg tctctaaagt gatgaagaga tgtttctttt gttgaaggtc
    38161 ctattcccat aatatccacc tctcttaagt catagctcta agggcaccat ctctgtattc
    38221 attaggagat ataatcatag gtacatttcc catatctata attgatgttc ctccttcaaa
    38281 tccactaggt tcctttgaga ataactgatt gtcatacata gcaccttgac ctgctatttg
    38341 ttttactatg acaacctttt ttgcatttgg tcgaattttg tcaaaatatt cacgaacttg
    38401 agtagcattt cttccgtctt ccattttcaa agacgctctt atttcttgta taaaatcatc
    38461 acatgctctg aatgctgcaa gtggaagtgt tctttcaaaa ggtaaacctc cctttaaagt
    38521 tacatctaca tggattatat aatcttcaac tgatggagtt ccatatctcc caaataccat
    38581 ttggtctttc aaaattcctt ctgaagaacc aaattcatgc atttgatttc catcttcatc
    38641 tgcaccagtt aacattacat atacacccgt taaagtatgt gtaataccct ctcccagtct
    38701 gcctaaaact tttgttgata ttggtataat gtccataata gtattaattt ctctgtcata
    38761 atctccaggt tttataatgt ctacttttat gtctgttatt aactcttctc tttcttttat
    38821 ttcatctata cttgataaat ctattgtaag tacatctttc tttatagaag tttttgaacc
    38881 gaaattaact tcattcatat gaaacggttt tataacaagt cttctcatta ttttttcttc
    38941 cataatatcc acctttgttc ttaaaacccc tctcctaacc gtgtaggaga agggttctat
    39001 attttcaaat ataaattaca ttttaaacgt gagctttata ttcgtatggt aatggaacta
    39061 tcttaccagc agatggtatt gcaactaatt gctctaatgt atctcttaat atatgtgttt
    39121 gcatttctat attatgtggt tcaccagcat tagcacccat tggaactaat ggagcaactg
    39181 ctctaggagt tccgttttgt ctaactactg gaggaagagc tgctattatt attgtaggta
    39241 ttccagcttc ctctattgct ctctgcacga tcacggcagt tctatggcaa gtacctcagc
    39301 cagctgtcat aactacaccg tctactccct cttccttaag tttagcagcg atagcaggac
    39361 cagtttcttc agtgaagaca tgttggtttc ctcctccacc catgaatgca tagtgcatag
    39421 gagctactcc tttgataaat ccttctgcag ctaattcatg taatctatct atagggaaca
    39481 tacagtttat atctttgttt acatctccat tgtcatatcc accatgtgat accatcattt
    39541 catcaactgt agctgtatta ggtatagctc taaatgtagt atctcctgct agattaaatc
    39601 tcttgtcaga ttttaaatga acaccagctg ctgtagctaa agctatagtc atatctttta
    39661 attctttagt tacaggagtc caaactggag gaggtgttat tggaacgaat atttcagatt
    39721 gaagtccttg tactgttgta aggctcatat atttcctctc ccttctattt tcaaacgatt
    39781 atttattatt tttcttcttg ttttgattgc atttctgctt gtttttcttt ttctctccta
    39841 atattttcta catactcttg attaggctct ggacttaata cctcaggata gcttagcatg
    39901 aatccaactt cttgacctat cttaagttcg tagtcagtta taagcattct attaggtatt
    39961 ttaaattgtc caagtctacc ttttaggtct atagtcactc caccaccttt gatgtcaact
    40021 ataatacctt cataaaaagt ctctgatgag atatatttta acctatccat tataattcta
    40081 cctctctata ctgttttaaa cttggatcta aatttatgtt attgtctaaa tcttagttag
    40141 tatctaaatt ttagttttcg tctttttcgt atatttctct tctcttctta ctcattggta
    40201 gagattgctc attctcttct aatactattt tttctcctgt aactttttct atagcttcta
    40261 tgttatttaa tttaacattt ggattccatt ttctttcagg agctttaact tctacacctt
    40321 ctatagcatt tttaagcata gccattattc taacagcatc ttctggagct aaagtgttgt
    40381 tagataatat ttcattctct ataccttgct tagacttatt gttgtctacc atgtgagtca
    40441 tgtatttatt accaacaact agagcacctt gaacagctga gaaacttaca ccaactactg
    40501 gtatacctct catacctatt tgctctatgt gagatgcgaa atctatatgg ttgtttccga
    40561 aaccttcagt agttactaca gctccatcaa cttccatagc ttcaactaac atacctaatc
    40621 tcttagatac atagaatttc tcagcattta cttgtggaga accaacaaat acaacaccta
    40681 ctaaatctat ttcttcgtct tccatagctc ttattactaa tggctctctc cagtaatgtc
    40741 ttgacatttc ttttgatgca ggtcctatac aagttaatgc atggatacca ccatctaata
    40801 cttcaagtgg agataataca actggcatgt ttcctaagtc aacgtttggt tgagctccta
    40861 atgtaccaac tggctcaact ggtaatatta ggttatcatg cattgcacct tgtcccatta
    40921 tttcttttat aacaacaact ttctttttac cttctcttct gtattgctct attacttctt
    40981 catcaactac taaagagttg tcaactttct ttaatgcttc tcttatttct tgagttacat
    41041 agtcaaatgc acggtgagca gctaaaggtc ctggtctttc catgttagtt cctgctttta
    41101 ttgttacttg acctttgatg aatatttcac ctttgtcagc agcacctggt ctaccccaca
    41161 ttatagtagt atttaactca ccttctgaag aaccaaattc acctatttga actccatctt
    41221 catctgtacc agttaatacc attacagctc catctataac tctagttata cctgaaccta
    41281 attcgccttc ttctttagta gcgattggtt gtatatctaa tacagcttca ctgtaagttt
    41341 catatttatc aggagttatt atttctaact tcatatctac aactaactct tgagtttcat
    41401 tagcttcttt acatatttct tctgcgtttc tgatgtataa agtagttcct tctattttag
    41461 tttcatcagc aaattcaact ttatctattt taaagtgttt tttagttaag cttcttaaaa
    41521 gtttcttttc ttcaactttt ggagctactt ctgctgctgc acttgccact ggagcagcaa
    41581 cgtttgctac tggagcagca actcctgctt gaccagctac tgataaaggt atctctaagc
    41641 ttatgttctt accttcacct atgtgtattt taactgtttc acctgcaact cctgtgctta
    41701 ctggaactac tgctgcttct gatactggag ctgcttcttc tactgtttct tctactactt
    41761 cttctttagc ctctcctgct ttgtatcctt ctacgttatc tgtagtcatt ggagaaagtg
    41821 catctaaagt ttcttttaac ttagctccta gtacttgacc tatagttaat ccattttctg
    41881 gtattgttaa taatccagaa tcctctaagt ctgcaaatat tgctggatct tctaagtttt
    41941 ctggcgctat aattgttccc gcttcaaatc tacaacaaca aactgctggg tcatttgcat
    42001 gggcttgagc tgtttctaaa gttattgaca tagtataaaa tacctcctta cattattttc
    42061 ttatttatta ttttaaatct caattcctca acaggtaacc ccttaactga gaaattaagt
    42121 aaattaaaac ctacataatt tgttatgatt aatattattt ttttctcact taaagtcact
    42181 ttatattata agcaattcct atgccaactt attaacaaaa agattttttc tataatagat
    42241 tcttcatcta tcgctatttt tagccaaata ttatataaat atttatttaa aatatgttat
    42301 tttttgtatt tgtaaacatt ttctcaaaca aaaaaagtgt caattaatca acactttttc
    42361 atttttttta acacatctat atacacaaca cttatacaag cattggcttt actaggtttt
    42421 aaattaaagt ttatcatttt gtcaaaattt agtcatgtgt catattttag acacatctat
    42481 tttgtattgg tctatcttat aatacaaagt tgttctgggt atatttaata tcttagctgc
    42541 tttagcttta tttccattag acattttaag tgccttggtt atattcttta tttcaatttt
    42601 ttgagttgcc ttcgttaaat ctaaaggata ctcttcttct tcagtactat tatttgtaga
    42661 atccatcata taacttggta catcatccac atctatttta gaattttgtg acaatacaac
    42721 aatattttca atcgtatttt ttaattctct aatattacct ttccatctat aattctgaaa
    42781 tatatctatt acatctttgc taattgtaag aacaggctta ttattttgtt tacatatctc
    42841 ctctaaaaag ctatgaacca ataatcctat gtcttctttt ctctctctaa gtggaggaat
    42901 ctttatttca acaacattta atctatagta taaatcttct ctaaattttt ctgcctttac
    42961 cattttactc aaatctttat tggtagctga tattattcta ggatttattt ttattgtggt
    43021 atctccacca actcttctta tttctttttc ctgtaatact ctaagcaact ttgcttgcat
    43081 actaagaggt aaatcggcaa tttcatctaa aaatacagtt ccatcttttg caagttcaaa
    43141 tatacctatt cgaccctttt tacttgctcc tgtaaatgca cctgattcat acccaaaaaa
    43201 ctcactttca aataactcat ttggtatggc actacagtta acaggtataa attgcccttt
    43261 tctctcacta taatcatgaa tagctcttgc aaatacttct ttacctgtac cactttcgcc
    43321 ccaaataaat atactactat ttgttctagc cacttgtttt gcaatcgctt tcgatttttc
    43381 cagtttataa cttttaccta aaatcttatc aaaactacct ttagataagt ttttgacttc
    43441 gttctttaga tattttaatg tatcatttac tttttcaagt tcaagagcta atatcttagc
    43501 ttctgtaaca tcaacttctg tacatacaac accgataaat tcttctttat aaaatatagg
    43561 atttgcatga actaatgcat acatattttc ttttttatct gtaaaataca agtcactcat
    43621 tccaacttta ctatttagta ctttttctga aatagtattt tccaaaaatt cattcatcgg
    43681 tcgaccaact atatcttcag actttatatc atacctttcc tccataaact tattccacaa
    43741 gataacaaca ccttcgttat ttatagcaca aattccttct ttaatttgac ctataatata
    43801 cttcaaagtc aatccataat cttctaaatg catatataga tagtccctaa tgtgctcttg
    43861 ttttagaact ccaataattt tattatctct aagaacagga agaatcccta tattttttaa
    43921 tatcattata tctctacatt catctaaggt taaaccttcg ttgacatata ttacatcctt
    43981 cttcattata agttttactg gttgaccttc atacttttta tgcatctcat aaagattatg
    44041 tatatccgtc atggatataa tgccttttaa ttggtcagat gaatctatta ccattagagt
    44101 ttttgtgttg ctttttatca tttcttttat tgcatcttca attcttgtgt cttcgtctat
    44161 agttgtaaat tttgtatcca ttacctcttc tacttttttt acttctggta tcgaaaacat
    44221 aaagtccccc ctttatagta gtacctcatc aaaacttatt tatatatatt tattctagca
    44281 tattataata attatttatt aaataattat tattaaaatt tattaagtaa ttagcattta
    44341 aatttatata atcactttaa aatttataat taaatttata caaatgaaat caaatgaatt
    44401 atacccttag tatattattt tttcaatact attttcacct tcaaaacatt tttctattca
    44461 tcaaacaatt aatgaatgcc tgtatccaat cataaattta agaatataat taaaatagat
    44521 atttttaaac aaactatatt tgcatattat atttacataa aaaagcccca aaatgactta
    44581 taaatcaatt tgagactttt tattttaaac ttaataataa tctagattaa tttcttttta
    44641 ttttacattg atacgctaat ccacaaattg caatgacact aataaataca tatgacatta
    44701 gctgagtttc atcacctgtt tttggtgatt ttactattgt atcatctctt gatagttctg
    44761 gagttttttc cactgtatca cttactggtg gtactggtgg atttaacact gtatcatctg
    44821 ttggtggcac tggtggattt agcactgcat cctccattgg tggcactggt ggatttaaca
    44881 ctgcatcctc cgttggtggt actggtggat ttattattgt atcatccatt ggtggtactg
    44941 gtggatttat tactgtatca tctattggtg gtgatggttt tggcttatgt ccatttgtat
    45001 catctgttgg tggcaccggt ggatttacaa catcatcatc tattggtggc actggtggat
    45061 ttacaacatc atcatcatct gttggtaaac ctatattaaa gttaacttct tgaccattct
    45121 ttttctctat tgtataactt aataaatttt gcttgctaga tggtaatgaa gatgaatggt
    45181 ctttttgtcc taaatcaagc actgccttat aatattgaat agcttttgga aaaatataat
    45241 cataagatac agcagaaata ttagctttgg catctggttt tccaacactc ttaagtttaa
    45301 atttctgttg cgttgaaatt tctacttcgc ctgtacctat tatattacca tctacatcat
    45361 aagcagttac tccatctggt agttttaact ttactacacc actataacct actaaggcta
    45421 cagcttctgt ttcataagta ccatcttcat ttttttcaaa gttaatctta gttaaaccat
    45481 tactcaaact aggttttcct gtatcatttg gctttaactc ttcacgacct gcttttaaca
    45541 atgcttctaa ataagctttt gtatttatcg ctacttcttt cctcttctga tactcagctc
    45601 tttcctcttc agtttttgct atttctataa gtttatcaca aaggtctata gagccttgat
    45661 actgcttaag tctttcttgt tcatctattt gtccaagaat aatccaaatt gcactttgag
    45721 tagctgagta agtcattatg tcattttctt cttcgcctaa attaaattgt tgcttatatc
    45781 caaatccatc aaattcagaa cctgcatata gtatagattt aactgcttct tcattttggt
    45841 tttcttgacc attaaaatct tctgctggta aatatggact ctttccatta ctacttggtg
    45901 gtcttaaatg attattgtaa caaaatgcag tttgctctcc atcttcacct tctattacat
    45961 atttgtcgtc ttttgagctt gctcctacaa gaccctttat tacatagtca aaagttaaag
    46021 tctttgtaat atcatcaaat cttaaatcat gataaggtct atctgaacca tctatttctt
    46081 ttagtaaaca agaatttttc acctttgctt ttttgtcata ccataagcta ataaatgagt
    46141 cttctgaagt aaaaacttgg ttaatttctg attgttcatc tgcctttaca tcttcttcat
    46201 cttcccaaaa gttatatact attttattta tttgagataa agtcatatca agaattttat
    46261 caatatcttg ttttaaactc atttcctcta taactatttc ttcttccaat ggtttttctt
    46321 cttctggagt ttgctcatct aatggtttct ctacatctgg cgtctgacta tctgatggct
    46381 tctctccatc tggcatctga ccatctgatg gtttctcccc atctggtatc tgaccatctg
    46441 atggtttctc cccatctggt atctgaccgt ctgatggttt ctccccatct ggtatctgac
    46501 cgtctgatgg tttctcccca tctggtatct gaccatctga tggtttctct acatctggta
    46561 tctgaccatc tgatggtttc tctacatctg gtatctgacc atctgatggt ttctctacat
    46621 ctggtacctg actgtctgat ggtttctccc catctggtat ctgaccgtct gatggtttct
    46681 ctacatctgg tgtctgatca tttgattgtt cttctccatt aagtattgta tcattgctag
    46741 tcacttcgtc agcataagat actattggtg taaatgcagt aaataccata ctaaaagcaa
    46801 ttactaaact gattatactt gattttttaa tttttgtttt caaaattctc ctgatactaa
    46861 aaacatatat tgtattcact taatataatt aaaattatta aatattatat gaatcttatt
    46921 caataataca tctttagtgt gttcaattag ggtcgttact cctaaccagt tctcctatga
    46981 acttcttaat atttctatta agcacagact atatcattac ctaaccataa attaggtact
    47041 ccccatttcc ccacacttgt aggtacgaga tttctctcta gtcgttgaag tttcttcttt
    47101 tcgaagctta cctgctgatt atccattttc aaggcactta ggatttaacc ttatgctatc
    47161 taactaattt tttctacttt cgtaacctca agtgcttatt aaatgcacac tctatcacac
    47221 ttatccttat ttcatgatta tgttgtggtt tagttagctt taggaacttc cagcaattaa
    47281 aggagttttg ggcagatatc tgccactcta cactcgttat gaatgcaggg agcatttcaa
    47341 aaatatattt atatctatct tctattaatt acttatttat gtatttattt tatatatttt
    47401 tgacaattaa aagttactcc tatttatatt tatagcaggt tgcactacta actccatata
    47461 tcttttaagt gcccaggttt aagatatact tcacagtttc tataaatagg ttttttaatt
    47521 tttctttttt aactttttaa gtgcactttt ttaacaactc aataaaatat aaattagtat
    47581 cctagatact tatctaataa aagacaaaaa ttagttttta taataaaaaa gatactatag
    47641 agtatcttca aatatcacaa aaacctttta ctctatcgga tagttgactt aatataatat
    47701 gcatattaat acaaaccaca tacttgagta tcattatttt tgtccaatat taattgtaat
    47761 agctattgtt atcattatac aatatctagc atattttgtc tattttttcc atttatttta
    47821 caatatatat tgccctcaaa atacattaaa aaacatcttt agaagtaact tttaagtttt
    47881 acttctaaag atgtctaact tctatttatc tattatttta tttttaatct tacgtcacct
    47941 tttattcttc ttattaatgg gtgattaact gttctcatta catggtcagt aatatgatat
    48001 acacctaatt ttaattttgg tgcagaaccc attactgtgt tactacagtc agtacagttt
    48061 cctattaata taacttctgc tccagctttc ttaaattcaa tacatttttg agcttgtcct
    48121 ggacagtgtc ctggattttc acattttaat gcacctttaa tttcttgagc ttgtttacat
    48181 ttttgaactg atactatatc agtaactccc attttagttg ctatatctct cattctttct
    48241 tcattaggtc cacatgcaca aactaaaaga cccatttttc tcttttcatt aacaaatggc
    48301 atagtaacta ttataccacc actagtttta gttattggag catctaaagt agtagcttta
    48361 ccagtgaaag gtcctcctag gattatttca ccatattcac cttttattcc accagctctt
    48421 tcaattaatt ctccgacagt tgttccaatt ggcacatctt caaacactat agattctttt
    48481 ccactgttta attgaccaac tacagttata tttttagata taactggtct tttttgctca
    48541 acagcctcta ctattctagt tagtgtttct acgtttatta ctactgcatt agcctctgaa
    48601 ggtaattgag ttggctcaag taattttcct agaacgtctc ttactattgc tctctcttct
    48661 cccattgggt acatatcaac tagttctgca acttctatgt tgtctcctgg ctttattact
    48721 tttttgaaag cttctattgc ttttggatgc ttacttttta ttgctagcat accttttcca
    48781 gcattagtaa cttccatagc atattttata ccttgataaa ctatttctgg tctttcttct
    48841 atttctttta tattatgagc taataaaggt tcacattcag ctgcatttgc taatattgtt
    48901 ccaccattta aatctatgtt taattttaca tgagtaggga atcctgctcc acccattcct
    48961 actactccag cttctttaat taagtcaagt ataccttctc cttttaatgg ttcaaaagta
    49021 tcttcttgta cttcatcagc ttcaattact atcgcttggt catttatttc acttattttt
    49081 ccactaacac tggcataaat atttgcccct aatccagttg gttctgcgat tagagttcct
    49141 ttttttacta catctccaac acttactact ggcttatctg gaccaccaac gtgttgtttt
    49201 aataaaatag aatatagttt gttcaactag tacgccccct taagtatatt aattttttta
    49261 taagctgttc aaataatgtt aatgctattt ttctattata aggtcttaac atattgttta
    49321 tttctataga acatatcgct tattaacaaa gcaatttcta tgccaacttt taaacaaact
    49381 tatacccttt ggaaatactg tcttacagca ttcattaatt cttctaaatt tttaaaccca
    49441 tcaaaaaaaa gtcaattatt agacactttt ttaatcaatt taatctataa ttattgatat
    49501 tgcatacatg tataaaaagt gtcaaaaaat agacaccgtc tttttatcga cacttttcta
    49561 acatatacta tataatttat cacaacttta cttaaaatat acatttatta cttattaatt
    49621 cttagttttt tgcactccat tggaatcaac tacataatta tctttataca acaaatcaga
    49681 tattttgact agactgtatc catctttttt tagtcgactt attatagtat ccaaatagtt
    49741 atctacatca tttatattag catggaataa aactattgaa ccaggttgag attcttttat
    49801 tactttctca attacatgat ttggtccaag ctccttccaa tctatagaat ctacatccca
    49861 cttaattact ttataaccta aatcactaca aatgtccata gctttattgt ttacgtcccc
    49921 aaaaggaggt ctaaataaat tagtcttttt tcctgttata ttatatattt tttctgatgt
    49981 agtttctatc tcttttgtta tgtcttcttt tgatatttcc ttcaaattgg catgagtgtt
    50041 tgaatgattt ccaatttcat gtcctttttc atctatagct tttacaattt cttcattatc
    50101 atccacccaa ctaccaacta aaaagaaggt agcttttaca ttatgtttat ctaaaatttt
    50161 taaaatatca tccatattat cagttcccca tgctacatca aaactcaaag ctattttttt
    50221 ctcatttgta tcaactttat atataggcat ttttgaattg tcagatttag aacatatgta
    50281 ttttattcca taaacaaaaa caaatattaa cactaataat aatgaaaaaa ataaaacact
    50341 atatatcaaa gctttagtcc ttttaacttc tcttttcata ttattccccc tttgaaataa
    50401 tttcttctat atttaaaatt tatttttttt cagctcaaaa aagtactgta atatttaatt
    50461 tataagacaa taactaaaaa aataaaacct atattgacct aattaaactc tctaaaatac
    50521 tcatttattt aattttttta tattttttac atttttacct ttatttttct gtatatatta
    50581 tttttatttt ggagaaatta gtattaacat cacataaata aaagtgttgt tagacatcat
    50641 aaactaatta tttgaggagg aaatttacta tgtcaaattc aaacagaaca gtagttccag
    50701 aagcaaaagc tgctttaaac caaatgaaat tagaaatagc taacgaaata ggtttatcta
    50761 actatgaaaa catagacaaa ggtaacttaa cagctagaga aaatggatat gttggtggat
    50821 atatgactaa gaaattagtt gaaatggctg aaagacaaat ggctggaaaa taaatagtaa
    50881 attttgacac ctgggtatca acagggctgc taattagcag ccctgtttct ctatatttat
    50941 ttataaaatt gtttttatat gaattattaa agattaataa tacaatacaa attgttcttt
    51001 taattttgta caaattagtt taatatatta tatatagaaa tagtttgacg gaggatgata
    51061 tttatgtttg aaaactcgtc tgaagaatta gcctatcaca aacttttaat tttatatata
    51121 ttagaaaaaa ttaaaatgga tttaactaat tctcaaataa ctcaagtagt attagagact
    51181 gagatgatga attatttttc attacaacag cttttatctc agcttatgga atctaagttt
    51241 ttgactacat ataaagactc tgacagagaa tattatgctc ttactcaaag aggcgtagaa
    51301 agtctagaat acttctttaa tcgaatacct actagtgtta ctgaaaaaat agacaagtat
    51361 atagattcta acaaagaaaa tctactagca gatactcaag taaagtctag ttttgtaaaa
    51421 caaagtgata atgaatttat tgtcaacctt agagtcatag aaaatcagtc taacttaata
    51481 gatttaaatc taaatgtttc atcagagaaa caagcaaaac ttatttgcaa taactggaaa
    51541 aataatgcat cttatatgta tgccgaagtt atcgatttac ttataagaga catacattaa
    51601 agcctacaaa caaattatag ttgtaggctc ttttcctacc ttgatttctt ttattaattt
    51661 gttatttgca gtttcataaa cttttactga attttcttgt gtatctgata caaatagtaa
    51721 cttttcatct ttagatattt ctaatccttg gggaatccca tttatttcaa tatttccaat
    51781 gtatctactc gttgtataat ctaaaattct tacattatta taacccaaat cagcaacata
    51841 aacttttttg ccactataat taaatcttat ttctactggt aataaaaatt catataatac
    51901 cttttttata tccatgctta cttcatctat tattataagc tttccatcaa gtgttgatat
    51961 atacatttct ttcttttgtt tatcaagttc tatatgccaa gctctaaagt ccatatttat
    52021 tttcttttgt atatttttat taattgtatc tatacatact atcgagttta tacacggtac
    52081 atataacttt ttgctttctc tatcaaagtc aaatccatgt ggcatattat caactccaat
    52141 aattcctatt ggatttaatg tgtttttatc tagtacatat atactattag aatcttcatt
    52201 tgccacaaac aattcattat cgctaagtac aacttgacta agacttcctc ctatagagac
    52261 agtatcaatt attttatcat tacttaaatc taagacatag agtatcccat tacttgaact
    52321 aggtatgtat attaaatttt tttctttttc tatgcaaaaa tggtgtggat atatattatc
    52381 ttctaatact atttcttttt ctagttcaag tgtagaataa tcaactatgc taatactctt
    52441 tgataagtag ttagaaatat agattttcat ataacccctc ctctctacaa tacatatact
    52501 acaataatat attatttcat tagcttgtat tatgctttat agttgcatta ttacgcatat
    52561 atttggtatt attattaatg ttaaaaaaag aaataatatt taatggaggt ctttttaatg
    52621 aaagtaacat ttaatccaag tggtgtatgt tgtagagaaa tgatttttga agttgatgaa
    52681 aataatgtga ttgttgatgc tgagtttata ggaggatgta atggtaattt atcaggactt
    52741 agaagcttaa taattggcca aaatgctctt gaagttgctg ataaattaaa tggtattgac
    52801 tgtggtggaa aaggtacttc ttgcccagac caattatcta aagctatacg tcaatctata
    52861 taattactta tataaacatc agtaaaatta ttaaaaactt attttatata aaaagagttg
    52921 tccatttttt agacaactct tttttatatt tttatttgta tacttatttt ataaaattat
    52981 aatttcttta ttaaagttct cactgtacca atcatatata atgaacctgc acttattata
    53041 atatcatcct cacttgatgt ttctaatgta taatttactg catcctctat ctcatgcttt
    53101 gatgttacat catctacata ttttaatact ttttctctta atatatctga atttatggcc
    53161 cttgggttat ttggtgttgt tgttattacc ttattaaaat gtggcaacaa tatctctaaa
    53221 acactatcaa tatctttatc ttctaacata cctattaata aggttaattt tctaccttta
    53281 aaattcttat caagtgcttt tgccaaagat tttgctccat cttcattatg tgcaccatct
    53341 attataaaaa ttggattttc ctttatcttt tctattcttc ctggccattt agtatttata
    53401 agtccttttc ttatagattc ttcatttata tttgctaatt tatttatgtc ttttagatat
    53461 tttattacac taattgccaa gatagaattg tttatttgat gttcgcctat caattttatt
    53521 tcaaggtctc tataagtttc tttcattaca gtacaatcgt atatttgaga atttatatct
    53581 gattttttta tgtttatatc atcaaaatca acttctatat atttagcttt tttctcttta
    53641 caaactgact ttataacatc ctttgcttca tcagtctggt catatactag tactactcca
    53701 ttttccttta ttattccagc cttttcgtac gctatttttt ctattgtatc tccaagtata
    53761 cctgtatggt ccaaacttat agatactatc acacttacaa gtgattttgt tattatattt
    53821 gtagcatcat atctgccacc taaaccaact tctaatgcca caaagtctac cttttgttct
    53881 gaatagtaat aaaatgccat tgcagtaacc acttcaaatt ctgttggata tgcatagcct
    53941 tcttttacca taatctctat tttttctttt attaactcaa ttatcctagc aacatcatcc
    54001 tgtggtatat tttgtccatt tactcttata cgctcagtaa aagtttctaa atatggagat
    54061 gtatataaac caactttata tccacactct cttagtatat tagaaacaaa agaacacaca
    54121 gaaccttttc cattagttcc agctacatgt attatattca aagtttcttg tggatttcct
    54181 aataattcta ataactttcc gatattttct aatcctaatc ttataccgaa tttattagtt
    54241 tgtgatatgt actctaatgc ttcttcatat ttcattatct aactccccct gtattggcat
    54301 tttctcttat gctatctaat tatagtatat tttttacttt taatctaccg acaaagaata
    54361 catataattt aataccttct acattaaatt tagctacaaa tctttattta taagttttta
    54421 tatctttcca ctaattcagt cagtgtatat attgaaacta agtcatattt tgagatgtcc
    54481 atataattaa actttatgtc aaatctatgc tctagctttt tcaacagatt aaaacaatta
    54541 tcataaacca agcctatctc cttattaaaa aggctaccct taaagagttt ttcattattc
    54601 tcttcaatat ctaagcaatc cctaacaacg tcagcaactt tcataaaaag agcattttct
    54661 ttgtcataca aatccaattt aaagtttaca attctactac actcatcaaa atcacaacta
    54721 tcccaatgat ttctagttgc taatgattca agcttatcat ttaaatcaga tattgttatg
    54781 cctggttttt ctgataatat cttagctatt ttaccagtaa gctttgctga taaataacta
    54841 ttacattttg gtggtaatct ataggaatta tttatatcac aacttatata tgaattgcta
    54901 tccataacac attgaacatc atattttttg ttgtaccaaa atgaatcatc tccatctaaa
    54961 gtaaatcctc ttacacctat aacattgtta aacatagctg gataacttaa gtcaaaatca
    55021 ttagcgagtg aacatactat tatttttcct tttctaaaca attcatagca aacttcaaat
    55081 aagcccttaa cactttctac tcctatgact gataaactta aattaattaa tcttatgtta
    55141 gtgtctaaaa ggtatcttaa tgcttcttca agaactttta tatttgtaat accatctttt
    55201 ctcaaaattt ttattacaaa taactctaca tcttcatact ctttctttat tattgatgca
    55261 caagcagttc catgaccatc ttcatcatca aatttatctg atataaagat ataatcatgc
    55321 atacattcaa aagcaattcc tccaactaaa ttatctttta agtaatcatg ttctttgtct
    55381 attcctgtat ctaatactgc aaccttaact ttattattca tatcacatat attctccatt
    55441 acaaaagttt ttaatatatc tatgttaata gttcatctta aactttgatt taagttgcac
    55501 aatttatctt ttaaatgcta tatttcttgc taaaaacata aaataagtac accatatatt
    55561 taatttatat ttattatatc aattattatc attaaatggt taaatgttaa gataaaattt
    55621 ttagatttat atcacaattt agaattattt gtaaaaaagg agattatctt tttattagac
    55681 aatccccttg tatattttat taatatttat ctatgattaa gcatcaattt tattttatac
    55741 tttttgattt taatactata catctaaatc ttatttaggg ggaacaatta tttatatgat
    55801 ataaaaatgc taatttgaat gaacttgtct tataatcagt tttagaaaat acaccattct
    55861 acaaagtatg aatcaaaagg tgaaaaaata ctaaaaataa taaatcaaca tcaattttaa
    55921 tcaatatatg aaaaacttat accaagtatg tataaaaact aatataaata ttattttaac
    55981 aactaatact tacaccttta tatattatat catatttcaa taaataaatt gcataaaagg
    56041 aaatcttttc atagaattaa actatttatt aattcattac tatagtttca ataaactata
    56101 agatgtcgct ttaatattta tattgtactc cattaaatat taatataatt aattaaagta
    56161 tgcgtagcta aatgaaacaa atatctatag agttttataa atagtcatta ttttaaaaag
    56221 gtaatcatat tctaaaaata catataatgc atataaaaat caataatagt atattgataa
    56281 tcaagctact aattaataat catgctacta taatggaacc tctacatata catgttaaac
    56341 catattaaaa atctataaac tgctattttg cataataaaa ctgtcttaat ataaataaca
    56401 ttttatatat taagacagtt tcaatcaata gccctgtgat gacattaaat cttttttacg
    56461 atattttcaa ttaccttttt aaaattaata cattatatca cataacaagc ttgttaatgc
    56521 tacttttaaa tctttaagtc tatacttact tataggtata aattgttcat taatagtaat
    56581 catattatcc ctaagatctt ctattcttct taaattaaca ataaaacttg tatgacatct
    56641 aaaaaagcca ttttcacaca gtaatttttc tgcttgtttc atgctcatat tagctttata
    56701 atctctacct attgtatgta cgactaaatc tctctttaca gtttcaacat ataaaataga
    56761 atctatcagt attctattaa atcctttttt actatttaaa actatataac gctccttctt
    56821 tctttgaagg ttatcaatac aaagatttac acccattgca aagttactat actctatagg
    56881 ctttactaaa tatctataag cacgaacctc ataaccttgg ggggcatact ctgaaaaagc
    56941 cgttgtaaat ataatttcta ctttttcatc aaactttctt atttttttag ccacctcaat
    57001 tccattgata tctttcattt ggatatctaa aaatataata tcaatttttt ctgggtattt
    57061 ggatattaaa tcttctccac aggaaaattc cagtatttga taatttagac atctttcaga
    57121 caaaagtttt tctgtaaact cttttagtat gcttctttgt attttttcgt catcacatat
    57181 aactaccctg aacataatat cacctccaaa tctaaaatat catttagttt actttatttc
    57241 aatttccaaa ctgtactcac tagctttcaa atttaaattt ctttataaat ttaaattgtc
    57301 gattaaacta cttatagaaa ttctctttaa tatttaaact taaattacga taaattccta
    57361 tacttttcta gatatattat gtaaaaaaat atagtaaaat aaatataata tgtatttatt
    57421 accctatatt aaacatcata atatatcaaa tttttattgc ttataaattt taagacataa
    57481 aattcatata ttcacaacat aaaataaaaa tataacacat ctgtaaagaa ttataacatc
    57541 atatttgtat atatataaag aaaaacatac aaaaagtata gaatatatac tttttgtatg
    57601 tttttactaa ttcttatatt tattttattt tagattctaa atttgttaat ctttcctcaa
    57661 cagatttaat catctcttca aatttttctt tttttgcttt ttcttcttca attaaacttt
    57721 caggagcttt tgctaagaaa ccttgatttg caagctttcc attaactctc tttatttcgc
    57781 cttctaactt tttcttttct ttagataatc tctcaatttc tttttcaaaa tcaactaatt
    57841 cattaagagg tataaatatt tcaacaccat caataactac tccaactgca tcttctggaa
    57901 cattagattt atcttttgct atctctacat ttgaagcaga tgctaaagtt ataaaatagt
    57961 ctttaccaag ctcaatagct tctatttttt cttcacttgg gattattatc aatttagctt
    58021 tcttagaagg tggtacattc atttctgctc tcacatttct tatacttctt ataccttcca
    58081 tcaataagtt catcatatct tcttcttcag ccatgttatc ttcttcatta tattttggcc
    58141 attcagatac tattatacat ccttcaacag taggaagatg agtatatatt tcctctgtta
    58201 taaatggcat gtatggatgt aataatttta atattttttc aagaacataa gttaatgtat
    58261 ataatgctgc agatttagca tttgcatctt ctccatataa tctaggttta accatttcaa
    58321 tataccagtc acagtattct gaccaagtaa aatcgtatat cttttgaagt gctattccta
    58381 aatcaaactt atccatgtta ttagttgctt cttttacaat attatttgct cttgatatta
    58441 tccatttatc agctagagtt aagtcctctt taacactttc tctagtcatg tttttaatta
    58501 tatcttcatc aatattcata aatacaaatc ttgatgcatt ccacaactta tttgcaaagt
    58561 ttctagcaaa ttctactctt tccatataga atctcatatc atttcctggg gaatttccag
    58621 ttgttaatgt aaatcttagg gcatcagctc catattgctc gattatctcc aatgggtcga
    58681 taccatttcc taaagattta ctcatttttc taccttgaga atctcttact aatccatgaa
    58741 ccaaaacatg gtcaaatggc ttttcattca tacagaacat acctgcaaat gccattctaa
    58801 ctacccagaa gaatattata tcgtatcctg taacaagtac acttgttgga taataataat
    58861 ctaaagcttc agtcttattt ggccatccta gagtagagaa aggccataat gcagaactga
    58921 accaagtatc taaggcatct tcatcttgtt taaaatgagt gcttccacat ttaggacact
    58981 tatctggcat ttttctagca actactattt ctccacactc ttgacaataa taagctggta
    59041 tttgatgacc ccaccataat tgtcttgata tacaccaatc tcttatattt tctagccatt
    59101 gtaaataagt tttatcaaat ttatctggaa caaattctaa ttctcctttt ttaagaatat
    59161 ctatagctgg ttttgcaagt tcttccatct taacaaacca ttgctctgat aatctaggct
    59221 caactactgt atggcatcta taacaagttc ctacattatg attatgctct tttatcttaa
    59281 ttaggtaacc ttgttctttt aagtctgcta cgatagcttt tctacactca aatctatcca
    59341 taccttcata ttttccacaa acttcattca tagttccatc ttcattcata gtatttaact
    59401 gctcaagatt atgtcttaat cctacttcaa aatcattagg gtcatgtgct ggagtcatct
    59461 taactgcacc agttccaaac tctaaatcaa cataactatc tgcaactatt ggaagttctc
    59521 ttcctactaa tggaagtatt gctgtttttc ctattaaatg tttatatcta tcatcttctg
    59581 gatttactgc tataccagta tctcctatca ttgtctcagg tctagttgta gctatttcta
    59641 aaaagtcttc actatctttt agtgggtact ttatatgata aaagtttccg tcgtgttctt
    59701 catgttcaac ttctgcatct gataaagtag ttttgcaatc tgggcaccag tttattattc
    59761 tatttcctct gtatatgtga cctttttcat ataggcttac aaaaaattct ataactgctt
    59821 cattacaccc ttcatccata gtaaatcttt ctttatccca atcacaagaa tcacctagtt
    59881 gtttaagctg attagatatt tttcctccaa attcatcttt ccattcccag gctctcttta
    59941 aaaattcttc tctacctatt tcatactttg tcttgccttc ttgttttttt attctttcaa
    60001 caactttaac ttctgttgct atagaagcat ggtcagttcc tggaagccaa aaagcttcat
    60061 atccatccat acgtttccat ctgattaata tatcttgaag tgtatggtca agagcgtgtc
    60121 ccatatgcaa ttgccctgtt atatttggtg gtggcatcat tattgtaaat ggttttttat
    60181 ctggatttgg tttagattta aaataccctt catccatcca ttttttatat agcctagcct
    60241 caaaatcttt tgggttataa gtttttgata aattcgtatt ttccattgtc ctgcctcctg
    60301 tattttataa ataaattttt taaatatctt tagaaataaa aaagagctct tcatcctctt
    60361 taaaaaggac gaaaagctcg cgttaccacc ttaattccaa agcttaaaat acattaacat
    60421 atcattaaat tattggttaa tgttatttta tcaactttga ctctcaaaga atttaacggt
    60481 tctaaccgtc taaacttact tatagttcag tttagaaact ccaaagctac attcagtaaa
    60541 tcttatactt agaaaatctt acagccagtg aattttcctc tcttttagta gtatttactt
    60601 actcctcttc ttctcagtct ttaatattac atattattat atacaaatat tattctcttt
    60661 gtcaattatt tttattttat tttttctgaa ttttcttaat tatgtctatt ctcttttata
    60721 tagttgttat attttaaaat atgtttttac agttattctg tcttataatg tcaataattg
    60781 caagattatt ttattttaat tttaatgctt tctcattaat tttatattat ccttacagta
    60841 tacctcttat tcgtattttt tatattatat gttttatttt ataaataatt tactttatct
    60901 tttactatat ttaaatttat tataagtttt cttgccagaa atttttaggt gttatatttt
    60961 ctgtaattgg caatattgta tatcctctct cttttaagat tcttataata ttatttaaag
    61021 catttaaact ttgctctttc tcatgaatta atactactaa ttcatctctt tttcttccat
    61081 aatataatat attacttact atctgacttg tagaagactt ccaatcctgt gtatccaaat
    61141 tccagtccca aattaaataa tcatttgcca taagtttatt atatgaacct tctggcatat
    61201 atggtttact tccgtatggt aatcttatta attttgaact ctgaccagtt atttcttgta
    61261 gagtattatt gcatgtatta aattccccaa ctgttacttc tgggctttta tataacttat
    61321 gtatatcatg acttacacta tgaaaaccta ttgagttttc ttcttccaag actctcctta
    61381 cttcttcctt gtggtttttc atattctgat taagcatgaa aaatgtcgct ttgacatcat
    61441 tttcttttaa aatatcaagt agtgcatttg tatattttga tggaccatca tctattgtta
    61501 tgtatgctac tttttcagaa gtagcccctg gaccttttgt ttcttcttga gatgctttgt
    61561 atatgatttc tcctaaagta ttactttgag aaagcagttc cagtgtattt tcaccttttg
    61621 aacttatatt ttcaactgga acattattaa ttttttcctc caataatgtt ccagttaaaa
    61681 ttaaaacagc tataataaat atccttataa atacatgaaa aacagcctta ttatctttaa
    61741 ttttcatccc ccatatctcc cttttataaa agcataagtt taagacttaa aaagttattt
    61801 tttatattta ttctctttct tattactttt tatatctcta ctaaatattt ttttaacctt
    61861 ttcttcttct ttttctccta aagattctac tcttttgatt cccaaagaag ttaaaaattg
    61921 taatacattt aaattatcaa atggagtttc catattcgta ctttcactat attcatcaac
    61981 attcttagta ccttcttcca cacttaaaat acgcttcgga cctcctacac agcctcctac
    62041 acaccccatt ccttctataa atgtagcttc tatttcttta tttagaactt tctttagacc
    62101 gtccatgcac tcttttgttc cttcaaatgc cttttcttca aattttatat ttttgtcaat
    62161 tcttctaact gataacttaa ctgctttact tacacctcct gttctagcat aaactctacc
    62221 tgaaagggac gcctctactc tattactctc atccattatt gctggattta actctaatgc
    62281 atcaaatatt tcttgcaact ctttaaatgt aagcacaaaa tcaactgcat cttttatatc
    62341 ttctaacatt gcttctttct tttttgccat acaaggacct atgaatacaa ctttagcatc
    62401 tggatttaaa atttttacag ctctcccaca agcaatcata ggagaaacgg atggtgatac
    62461 attttccaat atctgaggaa aactattttg tatcaaacta acccaaatag gacagcaaca
    62521 actagttata aagcatcctt cttcgtcctt tttcatatgc tcataataat catatgcttc
    62581 ttttgcagta agcatatctg ctgccaaagc aacttctatc atatcttcaa atcctatctt
    62641 ttttaatgca gttcttaatt taccagggtt tacatctttc ccaaactgtc ctacaaaagc
    62701 tggtgcaact attgcatata cagggctctt tatatctttt aacaatttta tcattggtat
    62761 aaattctatt ttatctgaaa ttgcacccaa cttacatctt gatacacaat caccacaagc
    62821 actacataca tcttcctcat tacaattaat atgcttactt cttatcttac atgactcatc
    62881 ttccttatta ttttcatcac aatatttgca agcatctgat attacagata ttattggtct
    62941 tttgacttca tctaaattta cagcttcatg tagtgactcc tttaaatttt tatctgtatc
    63001 tcctgtcaca tccaatccca tagttaccct aattaaattt accatagtat ctttatcaaa
    63061 ttttccgcta aaataattat ttaaattatc ctttaagtct tcatttaaaa ttttattagg
    63121 taagttttca atatcctcta tatcatcatt ccacactgct tttacaagtt cgccaaaaag
    63181 cttcatttta tatatttcta gtattttaga attgtcattt ctagtattca taaaaaatag
    63241 tacctccata aattaaactt atatatgttt aatatttaca aagatactat tttttattta
    63301 ttatttaact actattatta atatgattta tttagctttc tcaacaactc tatttcaatc
    63361 attattttca ttagatgata gttgaacaca gggctttttt cttcatctat attccagtct
    63421 agcttatcca cattatatgt tttcttaagg tatttatatg tatgctcttt caaataaagt
    63481 ttattttcaa gtaactctat agactgcata tgaaaatgta tttctctaca tatccttaag
    63541 gcattctcaa ttttttctac attagtttca ctcaaactat aatccaactc atcaataagt
    63601 tttgaatata tttcttctaa tttttctact tcttcttcaa atttctctac atttaaattt
    63661 tcttttctaa gaattttatc ttcaataagc aacattgaaa gttcttctat ctttttaaac
    63721 tcatctataa cactatttag ataatttggt ctagcaacat aataattaac aagtactcca
    63781 aacaaaacac ccacagatgt atctaacacc ctatgtaaag aataatacac agggtcacta
    63841 tttcctacac ctagatgtat agccagaaag gttacacagg caactactac tgactttatt
    63901 ttaaacagat tgcataaata tattgagcac attactccta gaccacataa aaatgggtct
    63961 ccagctttaa tgatggcaaa tatgaatcct attataccac ctaaaatagt accttccact
    64021 ctattgattc ccgtctttaa agaacctttt actgtatctt gaacagaaat tatacatgct
    64081 accagagaat aaaacatatt ctctactaaa tagtcaccaa gaatcataca taaagtgaca
    64141 ctaattcctg tttttatagt cctcataccc atcttttgaa gtttcaaagt tccacctcct
    64201 aaaaagcacc ttatataaaa tacgcatcct catatttaat atgttcctag tatatcacaa
    64261 ttttttaaat ttacccatta atcatatttt tttatcaatt ctttcttaat ttagacaata
    64321 aaaaaactgc tttaaagcag ttttttatcc tatctcaacc attttaccct caattgcaaa
    64381 aattatcttc tcacatacat ttgttatatg gtctccaatt ctttcaaggt atcttcctat
    64441 aagtagaagt tttacccctt ggtctatggt atttgagttt tcatgcatta tttttaaaca
    64501 atcgatttgt acttgttcat acaatccatc tacaatatca tctttaattc caacatcata
    64561 agctatactt gcatcaaata agattaaagc ttctctagtc tgagacatca tagacttaca
    64621 ttcttttgcc atcttaggaa tatctattag ctcttttata taagcctctc cacctatctt
    64681 caacatttct ctagctatat ttgctgcata atctcctatt ctttccagct ctatagatat
    64741 attacctaat gaataaataa atcttaagtc ccttgccatt ggttgcttta atactattag
    64801 ctctatactc ttatctctta tttcttctct taatttattt atttcttcat catcttctac
    64861 tacttttctt gcaccctcta aatccttctc tatcatacaa gtcacagact tttctattgc
    64921 ttcttcacat ttttccatca taagcactgt ttgttctttt aaagtatcaa tacttatatc
    64981 taaactatta ttgaccattg tctaactcct ttatagttat atattttaac caaatctacc
    65041 tgttatatag tcttctgttc ttttatctac aggagtggta aacatagttt ttgtatcgct
    65101 aaattctata acctctccat ttaagaaaaa agctgtttca tctgatatac gagcagcttg
    65161 ttgcatatta tgtgtaacta tgactattgt gtagtctttt tttaaatcct ctataagttc
    65221 ctctactttt aatgttgaaa ttgggtctaa agcagatgta ggttcatcca taagaataac
    65281 ttctggtctc atagcaattg ctcttgctat acatatacgc tgttgttgac caccagaaag
    65341 tcctagtgca gatgatttaa gcctgtcttt aacctcatcc caaatagctg caccttttaa
    65401 gctttcttct acaattttat ctaattgctt cttatctctt agtccatgtg tacgaggacc
    65461 atatgccaca ttatcatata tactcatagg aaatggattt ggcttttgaa ataccattcc
    65521 tactttagta cgaagattta taacatcatc tgaggtatat atgtcctctc catcaacaga
    65581 aatgtttcct ttaattgtta catcttcgat taagtcattc attctattta acgttcttat
    65641 aaaagttgat tttccgcatc cagatggacc tattaaagca gtaaccttat tctcttttat
    65701 atccatattt attttcttta atgcttgctt atcaccataa aataaatcca aatcttttac
    65761 actcattttt atcttatcga ttaattccat tattcacacc tcttaaattt aataattagc
    65821 tttatttaat ttcttagcaa caaatcttgc tagcatgttt agtgctaata caattactat
    65881 taaaacaatt cctatactgg ctgctgttgc tatatctcca ctctctttag tcagtaagta
    65941 tgagtgtaca gttaatgttc ttgcactatc aaatattcca cctggcatct tggctacagt
    66001 acctgctgta agtaatattg cagctgattc tccaattata cgaccaactg ataagattac
    66061 tccagataaa attcctggta ttgcacttgg aagtactacc ttatataaag tttgaaattt
    66121 tgtagctcct aatgccaatg atgattctct ataagcttga ggaactgttt ttaaagcttc
    66181 ttctgttgta cgaattatta ctggtaatat tattattgca actgtaagtg aacctgcaac
    66241 tatggaatat cccattttta atgtaactac aaagaaaatt cctccaaata atccatatac
    66301 tatagatggt atccctgata aactttcagt tgcaaatctt atagctgtaa ctgcttttcc
    66361 ttttttagca tattcttgta aatatatagc agccaatatt cctataggag ttgctacaac
    66421 tatagaaact actactgtat ataatgttgt aattatcatt ggaagtatac caccatcacc
    66481 tgatgctgaa taattgctaa ataagaaatt aaaattcatg ttgccaattc cctttataaa
    66541 tataaatccc actataacta ctaatgatac tattgtaaat agtgctgata gatatactaa
    66601 tgacttcaat agattctctt tgaactttct catcttaatt taccgcctta tttgaaagtt
    66661 tatttaaaac taagtttaaa attaatataa atgtaaacaa tactactcca gttgcaaata
    66721 gcatttcttg atgtgtacca aatgcgtatc ccatttcaag tgctatatta gttgtaagtg
    66781 gtcttacact atctgttatt gcagttggca taactggtga gttgcctgca acaagtatta
    66841 ctgccattgt ttcacctaaa gctcttccta ctcctaacac tactgcggct aatactccag
    66901 attttgcagc aggtaataca actttgaata ttgtttctat ttttgatgca ccaagtgcta
    66961 atgaaccttc tttgtatgct tttggtactg ctcttattgc tgtttctgat acagatatta
    67021 ttgttggtaa catcattact gctaatacta ttactattgc taacaaactt tgaccttttg
    67081 gaagattaaa tatactttgt atagttggaa ctatcactgc aagaccaaat acaccatata
    67141 atactgaagg tatacctgct aaaagttcaa ctgctggtga cattattttt gctaatcttt
    67201 taggtgctac ttctgctata aatacagagg ttaatatacc aacaggtact cctataacaa
    67261 gtgctccaag tgttgcaaat attgatgcta ctatcataga tgatattcca aacttattgg
    67321 cagaaggaac ccaatctgca ccagttaaaa agtctataaa tgaatatcct tcaaatataa
    67381 atggtcttaa tcctttataa aatacgaatc ctattatcaa aagtaaactt gcaactgcta
    67441 ctaaagcact aagtagaaaa atattttttg ctactttttc aattacgtat tttgtcttat
    67501 tgccattatt gtcatttttt tctaaaccta ctaatctaga ttttactatc ataataccct
    67561 cccattaaaa tatacttatc gattttcgtt ctgtattcaa aatttaattt tttataattc
    67621 gtcttcatca aatttcctat acttttattc tacttttttt aagttaaatc tatattagga
    67681 ttaagttaag caagtgtaaa attatattta ctttttaaca ttaattttac ttttaaaact
    67741 atatttgaca tttactttac aatatactgt tgtttctcta tattaaaata gcagatatag
    67801 ataataatac agtttatgta taatttatta cctatatctg ctattaagat ttgttaacta
    67861 aatttaactt ttatactaca tatataatta ttgtatcctc tagtttatat cactattatt
    67921 tccatcaaat tgttacgata cttgatgttt gcaataggta cgaatagcca aaaatataaa
    67981 aataggtatt tctatcaccg agaaaaacag tataatgtgt ggtgtccaaa aactcatacc
    68041 tcctaagtgt aagaaattaa atgatgtcat ttgatataat aaactaatct taaaaccaat
    68101 tccccctggc ggtaataggt atccaatcca actaacacct attcccatag gaattaagca
    68161 aatagaaaaa gcaatcagca tagaagtaag agaatcctta cattttgcag ataaaaataa
    68221 tgttaaacta accattgcaa gtattgaaat tagaccacca atagctataa gaatctgtgc
    68281 ttgtagtaaa tttatattta ctagactaat gacagaaaac aacatttgaa atgaggtttt
    68341 caaacattca gtaccaaaag ctaaatcaga aattgccaaa tggatagaaa tacatataac
    68401 aaacattatt ataaatatag aaaatagagc taatatttta gtaaacgcta gacgaatatg
    68461 tccatgtttc gtacaacgaa ggatgctatc tgattgtgtc tgatactcac cagaaaaagt
    68521 aggtgcagca attgcaacac atataattaa taatataaaa atataaaata ttatataatc
    68581 gaaagcatct tctggattta ttaagaaatt cttaatctta ttatttaact attttattat
    68641 ttaatatata ttaaaggtaa aaaataatat ataaatttag atatacaatt tatttatctt
    68701 ttcaaatata atctataaaa taatagttcc gttacgcatt tttttatata ataaaactga
    68761 ctgtaattta actggcaaag tctagaagaa taggctttat caattaaatt acagtcagct
    68821 attttataat aatttagttt agatattgtt agtatttcac atttataaca attattaaag
    68881 atattaatat atttattatt ccttattaaa ataataactt ttctattttt atatgattaa
    68941 taattgaaat ttcaatactt taaaatcaag ttttaatatt tatgtcagtt aaatgtcagc
    69001 aaaacatttt atccacaatt tttatataac ttttccacag tttatcccca gctttatcca
    69061 caaaaaggta gctactattg agtgctacct tttggcatat tcttattctt catcttcttg
    69121 caaacttctt aaccattctt caagcgcatc tattttatca atacttacct cttctttatc
    69181 atgtaatttt gatattaact gtgataaagg attattatgt aaacctccaa atagtttttt
    69241 agtttctgat tttaagtatt ctttttcttt tattaatatt gtataatgtg tgtgtttacc
    69301 tattttttga gaagctaaaa aacctctttt agttaacctt aataaaagtg ttagtgttgt
    69361 agtttgtttc catttatata ttttttccat ttcatctgcc acatcttttg atattacagt
    69421 tttataacca gtattccata tgtatttcat aatcttgaac tctgaatctg gtaatttttt
    69481 atttagcata atatcccctt ctttctatta acatataaaa atataaaatt atttttttcc
    69541 tagtttctgc atactttcta taaatacttt tatttgtttc tctgtctttt cttctttttt
    69601 atgtatagtt gtaaatactt gtgtaaaaaa attatcatat ttacttacat ctttttcttc
    69661 ttttattaca tctaaatatt cttttttagt tactaatact tcatagttta attgaaaacc
    69721 aactctcttc ttttttaata ttctcatttt tactaatctt ccaagtaaaa tctctgtagt
    69781 gctttttctc cacttatact tttctttcat tgctacttct atttcttttt tagatagagt
    69841 agacttttcc cttcacatgt actccatcaa cattaattcg cccctgcgta atttactttc
    69901 tacctcttgt cgctccattt atgtcacttc cttaattcgt ctaacttaaa ttaataatag
    69961 gagcttttta gaacaaaaac tataggtaat ttttaccata tattctactg ttttagtttg
    70021 tttttatata taaaaaatat tattcacatc tacaaattta tttaattttc aaacaatctt
    70081 gttgaacaat aactaattct attgtattat tttagttgta gaataaaact aaatcggcaa
    70141 aactagagaa atttagtgac gcaaagctat agggactaag acttatataa atatcttatg
    70201 agttatgtca gccagttgcc aaaaagatag tgttcttttt gtttttatga aagtttttta
    70261 gggggataat aatttatatg tttaaaaata aaatggataa atgtacacac atgttgactg
    70321 cttatattag cagttcgtat gattattgta attttttaga tacacagtta gatgatttta
    70381 tattagagta cggagaaaat gtagtagagt cttgtttaca ccaagtgatg gtattggtaa
    70441 gtaagtataa ttagatagac attgatttct agagaaccct ttttagtttt atctactttt
    70501 aaataatgat atgataaaaa attaattaaa atagatttat aatattcata gttttatttt
    70561 ttcttaaaat gcgatataat aaagatgtaa attcgtatca aaaacaaaaa aagaaactac
    70621 aatctattag cctagagcga agtttcaaat tcaaaataat ttaagtaatg atttattcat
    70681 tgaaatcgtc ttgattgccg tcaggacgat ttcttagttt atgtaaagat tcttttaatc
    70741 tacttataga atctaataat cttgttatag actttactat tgttgtaata gattttatta
    70801 caatagtaat gtaatacgct ataacaagta taaacataag tgttttcata tactcacccc
    70861 ctttcgttcg aaggtgattt ccgaaaactt tcgcccttag attgtagcct cttgcaagat
    70921 atattcttgc attttaatta taacataatt ttacaattat caaatatcca ttctccatat
    70981 ttttttattt atacaatata ttctatattg caataaaaaa cattgtttta aatatatata
    71041 cataggtata tactaaatat gttaaactta attatggaaa atataaaatg aaaggaataa
    71101 aaatatgact aagactatat tatgtgatta ctgtaataaa ggaataaaca aagatgataa
    71161 taagtatatt acttttcata agaaaagtca tatgaaaact aacatttgta ttaattgtgc
    71221 attaaatttg atagataaag ataaattaaa tgaaaatatt ataaataatc aacatggtta
    71281 ttcaaagaaa tgaaaaagca ctctccataa tgaagaatgc tctatataat aatgtttgac
    71341 ttagtaaaga tgtgttgggg ttacatattt acttttttat tatatcatat aactttgtgt
    71401 atgaaaaaga atttaaatcg attttaaggt gtgttgagta atgttcttga tagtttatac
    71461 attaatgaat ttcaaaaaaa taagcactcg tataaaagga atgctttaaa tgtatattta
    71521 tgaaatatgt aatataatta taacatgtct tatgttttag tatgataatt ttcgttcgtt
    71581 ttattatcac aggttatttt atattcaatg taaaaaatat aatactctac aatttatact
    71641 attattaatt taaaatcttt tgattaaaat aaatatcaca tataatttgt cttattctgg
    71701 tataatgttt gcaaggtcgt cttcaatact tattccataa gcagatacta tttgacctat
    71761 cattatgcca aaattccctc tcatttctcc tattgcagaa gtaaaaatcc aattagatat
    71821 atttccagca caacaagctt gcactctaaa attattatca tccttgcatt tactcaaaaa
    71881 cttattacaa gaatttctca tagctctaat atatccttgt aattcagatt tttcattaac
    71941 attcattaac tctgatgtta aataattttt tatttctatt acagaattca caactggttc
    72001 aatagtctca tattcatatg gagaatatag aactcttttt ggttcaagaa aaactataat
    72061 tcttctagca atttttcttt cactttctgg tggatcccat gacactccaa atattggaca
    72121 actaattcct gttagtttgt taaaaatctc aatctttctc attaatatcc ccctataaaa
    72181 ataaacttta cttaccttat tatatcataa tatttataaa tattataaaa tctacatgtt
    72241 tacatactta aatataaaaa atgcaaatat taacaaccat agttatttaa attctattga
    72301 aaataatgaa aaagttcatt atgataatag ttacgaaagt tattataatt taaaattctg
    72361 tgactttaat gattatctag taagtaaaga gcatgaaaat ttcaattctg aaaaataata
    72421 attttgattg cataaactaa tgataaacta tacaaatata gtctatcatt agctattcat
    72481 cattaactct acaatttttc ttttacaaat tctatagctt tatccaatgt tgaccacaca
    72541 tcattaccat atagttgagt aaatttttct cctgtagtct tactcatttc cttcatttta
    72601 ttacaagtta ctccaccgat tacatataga ttttgtgttc tatgtggttt atagtctttt
    72661 atatctgtta ctaagtaact ttctttttct ctcttataat ataatcctaa aatatctgct
    72721 gatactctat catcaccact gtacactatt gtgtgtttat acatttgctt cacctcatta
    72781 ctttcaatac tcttatttaa tacaccttct acaattaact tagccatacc ttcatatcca
    72841 agtttcttag ccttctcata atcctccttg ttatcacaaa agaaactttc aattagtatt
    72901 gcagtgggtt tagaactgtt taaaatatat aaacttttat ctaatttagc tcctctattt
    72961 ttaaatactg tacctagttt atcacatatt ctagttgcat actctaagcc tttattacta
    73021 taatatagaa cttctgaacc tttaccttga ccgttacttg catttaaatg taactctata
    73081 agtaaatcat atcctccact attaactcta ggtattttat aagacttttc ttcattctta
    73141 gttttaaact gcttttctgg gcatattatt acatctgcct tatgcccttc ttttctaaat
    73201 gtatctgcta atactggtgc aagagatttg ttgtattgat actcgttaac tactccatca
    73261 gcagaagtac atgctccact ttttaaaata ctgtgtccta ctgttataca tattttcatt
    73321 atttattttc ctccttcaac tgtttgtaag tttggtttat acctattgat ataccccaac
    73381 aaatcacgcc ttgtaagact gcaacaggac ttagtcctaa catccaaata gaaaatccta
    73441 taccaagtat taataacact actggaatat atttgttatc tagttgctta tacttcttac
    73501 agcccttacc tataatagag agagcagcta ctaaaattag caactgctct ggtataaaac
    73561 ttattaaatt atccatctct tatcctccta attaattaaa atattcctct ttgaactgca
    73621 aatataaaga accctacaag tgttgtaatc attgtaccaa ttagccattt gagcatactt
    73681 gtaagtgagt ttagattctc acacaatgct tttaactctg ctttagactc tatatttgct
    73741 atttttaatt cgtctatttc ttctccatgt ttatttattc ttgtttcatg tctttttaaa
    73801 tctgcttcga aaagttcttc attcatgaaa acctcctaat ttttgaatta aaaaagacta
    73861 tactatatag tcctctcctg ttatttcttt atattcactt gctgttatct tattcttttc
    73921 tactgctgtt ttaacttgct ctttagtcca gttgccattc ttataaaaat ctgctattat
    73981 cttataccaa ttcatactat atcaccccat tactcattaa ttgaaatgtt aaatctgcta
    74041 ttgtttgttc tgtagaattt actttatctt ccatactact tttaatatct gtatatctgt
    74101 aaaatacttc tttagtatct atatttataa ataactttgc ttctttattt tctatatatt
    74161 gttgtactgg caattcatca actaaaattc cactttttaa atcttcttca cctaatatac
    74221 ttggtttata gtgtatcatt ccaacatatt ttatattttg ttcttctgtg tccattaaat
    74281 ttcctaaata aatcattaaa gttcctctcc ttctttttga attaaaatat tagatactaa
    74341 tatagctaaa caaatacctg aactactagt aaagcatatt ttgttattac ataaagttac
    74401 aaaagatttt aaatctgaat gacaagaata ctcagttatt tttttaaaat ctgatacatt
    74461 tattttttct aaatcaaatc tgcttggact actccatgca gaaactgaat aaaggtatgt
    74521 tccatctgta attaaatccc tatttggaga atatgtatca gctcctaatt cagttaaatt
    74581 taaatcttta tcaacaacag ataaagtttt actcaaagct gactctatat ttctttgttt
    74641 agtcaaataa atcttgtcac ctataaaaac aaatcctttt acatagtctt tatagggcac
    74701 attattataa attgttaatt gtgtatctat attcagtgta tttggattca ttttacataa
    74761 atattggtaa taatcattat aactattttt tttatgtttt gctttcataa aataaatgtt
    74821 atttgagttc attacaaatt tttcgtggta tctaaactca tatgtgctat tatctgttcc
    74881 atctccattc tctataatgg ttgacaaatt taacttatct attttgataa acttttcaga
    74941 tggtcttact cctccaagcc cagaagttac aactgcatat aaataatttt catctccaca
    75001 catataaaga caaccaatat tagtacgtga agaaacaaga ttcccacttt ctttgtcata
    75061 tttagataga ttatacacat ctcctatata aatataattc tcatctatat aggcaccatc
    75121 tgggttataa gtaagtctat ttttataaat taaattgaaa ttagaatcca ttttatatat
    75181 ataaaactta gctactataa agtaacaatc tatatcgtta tgaaacaatg tcatctcttt
    75241 tacgtcttca tcaaatattt tatttatgat aaacctttta ttagtaaatg tagtttcaaa
    75301 caaagcgaaa ctacatttac tatcatttat tttattcttt atttcttccc atgtatcgct
    75361 tgtagtaacc tctgcgccct tggagtttaa tgctgttact acattatttt tagcatcaac
    75421 tccagactga aaaacctctt ttaaagcatc ttctacatta tcacttgtaa aattattctc
    75481 tgtatcttct atagttactt tctctgcttc taatacaaga tttctaactt tattaactaa
    75541 ctctttaaaa gtcatttaat cacctctttc aataaaaaaa agaacctact aagctgttgg
    75601 ttctattcct tctactactc cactctgttt aattatataa tcctctactg cttttctata
    75661 ctctgtgtta gttacgtcat ctaattcaaa ttctcgattt tttaaaggat ttaagcctct
    75721 acttaaaatc ctctctgcta atattcttac tacaacatta tttatattca ttataataat
    75781 cctcctactt tttcattttc atttagtaat aattggtttt ctaactcttg tattctcttt
    75841 tcttcttctg aaacgaatat tggtatttct tccaaaattg gttctttcgt ttctatattt
    75901 atacctgtaa ttctattttt tgtataatct atacttccat actcaatgtc aatgcaatgc
    75961 aattctgtta tttcatcatg ttctaatata tcccctgttg cttctccagt ttgtaaaagt
    76021 attttgcctg tttggtcgta aattattcta tttgctctat tcattttatc acctcattta
    76081 tttaaatttt atagcacacc aattaaaatt aactggtata ttagtgttat atgcaggcag
    76141 attaagacca agattagtat tataccaaac atcctgctct tcaatattga aaatatcacc
    76201 tttaacgcta aaggtattaa catctatttc acgactaaaa cataaacgaa tagtaaaatc
    76261 tttagtaaaa acaccgcaag aagcaaaaat aagatgttta taaaatttac catcataaat
    76321 atattcgcat tcagcaataa aaatattagg aacagattta aaacctccaa ccctaatcca
    76381 atagccagga tacataccag atgcctttcc ataaaaatta gctatacaaa tactattgcc
    76441 aatgagagtg gtaacaccac taaaatattg atacttagta tttaactgtg ttatagtatt
    76501 attagattgc gttaactgat tcatcaaatc ttgtacacta gcgtcagaac tatcaaaaga
    76561 agttttaatt ttctctgata actccacaag tgtattattc aaacttgctt ctatattctt
    76621 taatgctaaa gtatttataa tacttgtttt accagtttta aatcctgcat taacttctgt
    76681 cagttttgtt gatatatcat ttaaatttac attttcgggc agtggcatta tattcttact
    76741 tatacttaac actttttctg ctgtagcatt attactgtct gtaacaacta tcttaagtgt
    76801 gtgtagtgca ttatcttcta atgtatagtt aattgttttt tcaagagtta aatctgttgt
    76861 gatagtttct tttaatacat catctataaa gtattctatt ttagttaaca atgctgggtc
    76921 tgtgtggtcg gctttgaatg ttgctgtagt tgagttataa gaggatacgg ttaaaaaagg
    76981 taatgcttgt agtaatgtta ttagggcata accataagca ccagcagtat ttccaccaga
    77041 ttccataaca acattatcaa aataatattc agatgttggt gtgtagccag taggcttata
    77101 actatcttta gttaatatgt agccacttcc acctccacct gctcccacac cattcattcc
    77161 tgcaccacca aaccagccac ctccaccgcc ttcgccagtt gaatctttag cagaacaccc
    77221 ttttccaaaa cttccgtttt ctgtgcttac acgaccaata ccaccttgat attgagtacc
    77281 gccgggacga tgtctgtcgt tagcactata cccagtacct cctgctaatc ctcctcctgc
    77341 accaccagta taaggagaat atgaaccacc gccaccacct gcgacaatta tacgagatag
    77401 caaaccttgc tcattatccc aagcaccacc aacgagcctt atatcagtag caccaccacc
    77461 gtacatagaa taataagtac ccataacctg ttgatttaaa taacctttac caccgccatt
    77521 aaaaccactt ttagtgttat tactcgtaga tgaagaagca aaaccacttt cgccgacgta
    77581 aacatataat gtagtttgtt tttttaatgt aatttcacct ttagaatatc cgcctttagc
    77641 atcagtatgc caagaagaat tgttgatacc tccagaagaa ccccagcatt caaatttata
    77701 tttgccaggt ttcaatataa cactttgtgg cgaaccatta taaccaaaat tccattcagt
    77761 ctgcattttc tcactctcct ctctaacaat aagttattaa ctcatttaca ctagttgcaa
    77821 tattagataa accaccattt accttttctt ctagattaac aaatctatct tcgattttct
    77881 tagacgaata agtagtcatt tcagatactc tgttatcatc tacagttgca ttaataaaat
    77941 gagtttctgc atttccattt atcacataaa cgtttaattc tgaccttgtt tcacttctaa
    78001 cttctataga attatcatct ataattttaa agtttgtaac tgcattttct tttgtagtag
    78061 catctataat atttacaact attctctgtg ttaataaact atgtgttaca gttgctttga
    78121 atccattttc tgcatcctca acccaatcat caattgttat tatttgagta gatgccacat
    78181 ttgaaccacc tgcgattaat tggtcaattt taatattttg tttctcattt tctgtgtcaa
    78241 ttctagtgtt tagctctgtt ttagtagttt ctatgttgct tgttaattct gttttggttg
    78301 tatctatttt agtgtctagt ttattaatat ttgttaatat tttttcttca tcttttttag
    78361 ttagaaaaat agctgtaggg tcaacaacta atgtcacttt ctctacatta gatacttcta
    78421 tgataaattt caaatacaaa tctttcatag ctccattatc aacttttggc ttgtaggttt
    78481 cagggctttt acaaactgca atcatatctc cttcattatc tataagaccc atttctctaa
    78541 ctgtaaatcc acctatcgaa ccagggatac atgctgttgc aataatccag ttaggattat
    78601 tttcatcatt atcaaaagca tttatattcc cttcccaaac tttatttttt aatgctgttt
    78661 ggtcttctgt tggattatag tagtttcctc caccatcacc tgcttgaatc ttctctaaaa
    78721 ttactgactt acctaacatt cctgcattag caatcttagc tttacctatg tttgttagta
    78781 ttgtgtaaaa ttgttcatca gccatttatg ccacctccta tcttggatat actgttaatg
    78841 tttctgagct catgttatga gctagtgcaa acttggcttt aacacttgct tttacttctt
    78901 tgcttgtgta cggatataca gttatttctt cgctcataat tgccgtttgt gcaaaatagg
    78961 ttttactttt caataaagaa actaacttat aacttacagc taaatgagaa ggttttataa
    79021 catttactct cttatataaa tcttctaaat ctttaggaaa accttgggta ctggttaatt
    79081 caacaccaaa agtatatgga gatatatttt catttatttt tatgtttgca cctgtataag
    79141 attggagtat catagccatt cttttaggtg tcataatata tttactttga agcttagcaa
    79201 tgacctttct tcttctagct tctatatctt catctatatt agtggataaa cccactctat
    79261 tttcccaaaa ttcaagtccc catgtcgcac tctgagggaa taattgtaac tctatttctt
    79321 tatttaataa ttctagatta tcaaattcgc ttcctatagc ttcatataag ctttgcatta
    79381 tgatagattg ttcatagata ggagataatg taagaagcat ttctttacct tttttagaag
    79441 ctatcatcca accacctcgt taactatttc ccctattccg accacttggt cttgcaattt
    79501 tatattttct tttacatcat ttatagtaag attagaaaag tcttctatac cttcatctgt
    79561 cagcatcata gagcctacta tcgcctgtat agcattgtat gagactgtcc cccctaaatc
    79621 aatcttatct aaatatttat ctatcttagt ttttagattg tttaatacag tttcttcact
    79681 aaagccatta ctaaatataa aactagcttt tacattaata agtaatgtgt caggtgtcac
    79741 aactgtaact aatgcaccga taggagcttt cccatctcta ttttctcctt ctgatatatt
    79801 caatggatat atatattctt ggaccttatc tattaattct tgtgttgctg cttttctgtt
    79861 tttatctagt attaatactt ttactgtccc tgctccattc cattcgggaa ctacataagc
    79921 atatcccact ccatctactt ctttagccca tcttatataa tctgaactag ctccactaag
    79981 tttatcttct tgttctgcta caagaactct ttctctaaaa tgttcttcgt cttcaatatc
    80041 tgttccacct ttgaaatctt ctttattagt aactgattta ataccattaa tagaacctag
    80101 caaaacggct acactacctt tagacacatt ccctataatt cctgcaactc tacattctgc
    80161 tttaatatct actgtttcat tttctcctat agttttagtt tcaagaagct caaattctat
    80221 gctctgtttt tcatcagttg caatagtagt tactatagtt ccttttgtaa tgatagttcc
    80281 ttgcatacct gtaaatgtaa taactccagt agccttagtt ggttgatttt taaatactcc
    80341 tttacattca ccaagccact ctaaataagt tccataagag gtctgaggaa atgctatctt
    80401 taaattattt tgtaatccta gttgttttaa ttcggctatc tgctctgctg taggtcttgt
    80461 tgcatcataa ataaagtccc cttctagtgt gctcacatct tgaaagttac ttaacatcct
    80521 ttcatgtaca gagtcctcat cttctgttaa aaatactggt ataggtagct ctctttgcat
    80581 ataatcacct acctttttat attgccatca attactatat tttcatcatc tattgttaat
    80641 acattaaatt catactctac taacctgcta ttctccagcc aattaaaact aaactctcct
    80701 acttcttttg tgtaaggatg cactaaaaga gtttctttta ttaatctagt tatttcaagc
    80761 tcttttgcat tttgtgataa gttactagcg attaattctt ttatttcact tccatataca
    80821 ctagaataag ctgacctttt gtgcctaggt gttaatatag ctttctgaca ccattgtttg
    80881 tacgcttgaa ctttatcgca tttttttaat gttccatctg catttttaac aaattcacct
    80941 ttttcaaaat caaataaaaa agaacccttt aggtccaatt cattttcatc attatttttt
    81001 aattctacag tttcaaattt ctcattaatt ggaaataggt ttggcattta caaccctccc
    81061 aattactgca aattcagctc ccatgactgc tactaacacc ttatcgccta tagccaaggg
    81121 ttttaattct tttgtagttt ctattttatg cttatgccta tattctccac ttaaagcttc
    81181 atctgaaaaa gtaaaataat cctcttttaa tattaaactc tctaatacta aataatcttg
    81241 tatttcatct ttataaccat ttacttttaa tccatttgtt gttatttctg caagttcaca
    81301 acccattcca aaagtgctat ttgctacact tttattcata ttttctttca atattctagc
    81361 aattccatta aatctagcat cagtcattgt tataaaactt cctccttata tattctaaag
    81421 tccctatatt gagcttcatt ttcagtctag aatctagtgt atgagtgaca tctataacat
    81481 aatattcttt actttttaaa cttaccttgt cacctgctct tattctattt atatctactg
    81541 cacaatctac acttattgtt tcctctccac tattgaacat tgcttctgct gctttcttag
    81601 cttctttagt attttttatc ttttcatctt gtttaatctt ttgcagtgtt ccatatttgt
    81661 ctgagtcctt tttatatgtt ccaatgatag gtgcttttgt attttcatct ttactctttc
    81721 ctaaaacttt tacacttgtt actgcatcat taaaactact tgtaaagttt gcatcttcta
    81781 atatactatc taatttatat acatttgcat tagtaccaag cttaaatagt tttaatttat
    81841 tatccatcct tactctaaat aagtctccac ccttactcgc tgtttctttt aagtcttttt
    81901 taatcatatc tagtatattt gtcttatgta ttactttagc aagttttaca gaagtattcg
    81961 ctagattgta gtaaggtata ttccattgtt tgcagtagta ttcaattctt tgtgttgctg
    82021 tattttcttt aaacgaatat tgttcttctg attcttccat gtaaacagtt ctttctctac
    82081 aagataatgt cagtttttta ctcttttcac ttctcctagt ttcccatatg actccatcaa
    82141 agattgtttc ttctttttta ctctcatatg caatgtcaat tagaactatt ttatcacctt
    82201 ttttaatcca tatatcttga agttgtttag gttctactaa tgatacatcc atcttatatg
    82261 caactccgtc tatagcttca cttaatgtta ttccctcgtt aaaatttgca atatcatatt
    82321 ttccatttaa tattattttc atttagaagg tatcaccaac ttttgtcctt ttttaatcac
    82381 attcggattt ttaccaatga cttttttgtt ttcgggtata ttgtaaattt ctggccatct
    82441 cgaacctttg cctaaaagat ttttagctat cttatataat gtatcacttg acttaacagt
    82501 atatattttt ggagtggttt tattattagg tctattgtct tttaaatctg ttttagtatt
    82561 acttttagtt tctttcttta atgtctctat cttcagttct ctgtaagttc taaatgttat
    82621 ctcaatatct ctgtcttctt ctcttcctgc tgtttgagta ttactaaaat tagatattgt
    82681 aactaatcca ttgtagccaa aaccagttac tattaatcgt aatggttcag cttggtctac
    82741 ccacttttca agcattgcca ctacttcgat tggatttttt aactcactgt atctgcaata
    82801 agaagcgtca tataagttag gcagaaatgt tttaaatgat atttctctta tcttctctcc
    82861 ttctttttta atgtcaaatt cgcctaagtt tactatatct acagtttcaa accttttttc
    82921 ttttttaata gataaactat cgaatggatt tactggaaaa tgaaaatcta ttttttcttt
    82981 ttcatttttt aggtatatgt ctattaccaa attatcactt cctttttaca ataaaaaaga
    83041 catctattcc taataaataa acgtcttttt cttatatatc taatttttaa aatctttgaa
    83101 agagaaaaac tccatattat ctacactctt aatattatct tgaactttca agaaatcatc
    83161 tatattaatt tgatatgttg tttgaccact tgaacctaca aaatatactt ctgctgagtc
    83221 tattctaaat tctttcaact tgttaattaa gtctttagta aatgccttac aactgctttc
    83281 attgtcaaaa cttgcatttt gaacttgtaa actaagtaca tagctaccat ctgtatctaa
    83341 tacatcattt gtgtaataat ttcctttata ctctgctgga attatagaat caactttttt
    83401 ctttaattct tcactagtta atgtttgctt tttcgtttct gctttctctt tattcttctc
    83461 ttgatatttt ttatctactt tttctttttt ctcagtttta tctcgctctt ttttttcagc
    83521 ttctgtacct tcatttttct gtttctcttg ttctttcttc ttatttgttt cttcttctgc
    83581 ttctcttgtt gctagatttt tacctggctc ttcttttaga tgttcttctt gttttttatt
    83641 actactattg ctagttgtta tattatcttc taacaaatac caaatacata caaatgaaaa
    83701 tgtaataaaa actaaaaata cgccaaaaac aactttaaac ctttcgtttc ttttaaaaga
    83761 tttaactaca aattctatag aaaatgctaa taaagttatt ggaaaaattg ctatagcaca
    83821 aactaaaact aaaaccttta agattatact catattttta aatcttcccc acataatatg
    83881 caaatccccc tcatgtaatt tataattaaa ttataacatc tataaggagg atttttttaa
    83941 caacaattcg acattatcca atgtcttcta atgcttctct taatccactt tccacttgag
    84001 acaatatttc ttgtatcatt tcttctttgt tgttgctacc ttgaatattt atagatattc
    84061 caccaacatt aatcgcatta cttccactag aaattatgtt ttgtggttga gcttcttgat
    84121 aaattctatt ttctgtatta ttaaattctt cttgtttggt aggaaattgt ctaacattat
    84181 taataatact agaattacta ttttggatac tacttgcaga attaaaacta gttcctaatt
    84241 tttgagatat tggaataaca ttattgcttg ctttagttcc aagcatctgt cctgcttgtt
    84301 catataaact taatgctcta cttctcttac tattagaaag aggaataacc atttcaggac
    84361 ctgcttctcc acaaatactt ggtttacttg caactccacc atcagcaaaa cggtccaata
    84421 cattacttat tccagttttt actatactta caaaaccagt tattttttgt gataattttt
    84481 ttcttaaact atcccatgct gatttaattg aatccacttt acttttaaat ccgttttcta
    84541 caagacttac aaatccactt attttgccag ataaatttac tttaagtcct tgccaccaca
    84601 ttccaacttg ttgaactttt tgttgaaaac cattgcttac aaaactaaca aatccgctta
    84661 ttttttggcc tacattagtt tttaaatcag accaccattg ttttacttgc cctacttttt
    84721 ctgaaaatcc attatcaata aaatttacaa ctgctttaag tggtgctcct aaaactcctt
    84781 ttataccttc ccacaatgat ttgactactt ccccaattcc tttgaaaaca tcagaaaatc
    84841 cttgttttat tttttcacca tcaccactaa ttatcccacc tatgatttcg aatattcctt
    84901 ttattatatc aattacacct tttatagcac ctgctacagc atttataata gatgcaattg
    84961 cattaataac agaagttata actaaaacta tagaagttgc tacacctttg agtaatcctc
    85021 cccctatatc tcccagagta gatgttaaag aatcttttat ctgttttaaa tagtctataa
    85081 aaggttttgc tgcttctttt aattggttga aagcatttcc taactctttg aaagatgttc
    85141 caacacgttg tgttgattgt tttaactcat ccatattggt tttagttgtc ttagttgctc
    85201 catcatcttt aattggctta aacaaatttg aaaagaaatc ttttattcca ctaaatgctt
    85261 cttttattgg ttcaagagct tttcctagtt ctgcaaagct agattttaag ttatcaaaaa
    85321 ctggttttaa actttctttt gtttctaaaa ctttttgttt taaattttcg aaaggcgttt
    85381 taatattttc atcaaataca gtttttaaac ctccaaaagc ttcttttatg ctatctaaag
    85441 aatctccaaa aacttctttt aaattactta atgattgttt aaatgtatct atagcaggtt
    85501 ttatgccttc taaaagttta tcttttaatt cggttgcttt gcctcctacg aaagatacta
    85561 tattattaaa tacttctgtt gcagatattt tgagttctcc aaatttatct ttaatttttc
    85621 caataccttc acctattttt tgacctaacg aacttatata tgcttttgct ccgtttgatg
    85681 aagcttgtaa ctcgtttgat gctttctctc cagataaatt gacaggttga acttttggag
    85741 ctgctttagt aggatttttt aagaagtctt ttaattcatt ccattttttc tttattccct
    85801 ctactttttt tccgaatttt tcgtctagaa catctacaac agcttgaata ggagaagtta
    85861 caatatctac taatcctttc caaacagaag aaacaatttt tattcctcct tcaaatacag
    85921 attttaagcc atttattatt tgtttcccat caccacttat tattcctcca acaatatcaa
    85981 aaactccttt tataattgat gttaaacctt gcaatacacc tgttatcgcg actacagcag
    86041 atttaacagc ttctacagca gctacaaaag ttaatataaa gccagctaaa acattacttg
    86101 ataaaaacaa aattataggt ccgattttac tcattagcgt tgatgcaaaa tccccaaata
    86161 cttttaacaa tggaattaca gctttcccta attcttttaa tttgttacca aacacattta
    86221 caaaaggtga aattgctatt attgcttctt gtaaaaaatt tttaattgat tttcctacat
    86281 ttttgacaat ttttctaaaa gcatctgatt tttgataagc taatgtaaat gctgttgcta
    86341 gtaatactac tcctgctata acagcaccaa caggtccacc tagtgcaaac aataaagctt
    86401 ctcctagcgt tgccgcacca cctgcaaaag cagctattgc aaatcctata tcgcttaata
    86461 taggaattag aaaagaaata aactttaaag ctttgaaagc aataaatgca gatactattc
    86521 cagatattac tgaaatgaca ttttgcataa tacttttaat tttatcaaaa tcatttataa
    86581 aatcacttac aaaactaacg atggcatccc ctattttagg catatctttt gttaactgtt
    86641 caacaaaact tcgtgtcata ggtccaagtc tttgacctac tgatattctt acatcatcaa
    86701 tagcactttt taaaatttca aattgtcctg acagggtatc tagtttcata tcagcaattc
    86761 tcttagcttc tccttcactt tcatttatag ctgttgttaa ttttttaaaa tctttttcac
    86821 ttgcgtttac tacagccgcc caaccggcca tggctgttcg cccaaatatg ctacttattg
    86881 cagcactttt ttgtactcct tcaagtccgc ctaatttttc tctaaggtca acgattgtac
    86941 tagctaaatc taaatttcca tcttttgttt tctttatttc tattccatat ttattcatag
    87001 ctttctgtgc ctcagctggg ggttttatta atctaactaa accacctcta agtgcagtac
    87061 ctgccatgct acctttaacg cttgcactag ccattaagcc agttgctaaa ctcaaatctt
    87121 tcatagaaac acctaatgct cctccaacac ttcccatata cttaaaagtt tcacccattc
    87181 tttctatgtc tgtgttagag tttgtaactg ttgctgccat aacatcaaca aacattcctg
    87241 tatcctttgc agttagccct aaagcagtta aaccatcagt cacaatatct gctgttagtg
    87301 ctaaatctgt ctgacctgtt gctgccaaat ttaatatacc aggtagacca gcaatcattt
    87361 ctttgctttt ccatccagcc atccccataa aatacatagc attccctgca tctttagctg
    87421 taaagctagt tgtacgaccc atttcccttg ccattgcagt catttctgcc atttcctttg
    87481 aatttgcact tgatacagct tgtgcgtttt tcattgcttg ttcaaagtct gcaaatcctt
    87541 ttatagcact tcctactcca acaccaccaa ttaatgctgt ggctgttact gctaattgtg
    87601 taaacttact aatagtacta cttataaaag aacttatctt accatctaac ccactcaaag
    87661 ttggactagc ttcatctttt aattttacaa ttgcttgata agtcctatta gaaaactctt
    87721 gtaatttact cttagtacga gaaatagtat ttaatgcttc ttcacctttt gctttaatat
    87781 ttattattgt gttgtttttg agttctccta acttacttct agtttgagaa ataactctta
    87841 gtgctgggtc agctttcata ttcaagctaa ttattgtagc cgcagtcaaa ttttgtacct
    87901 tagcttttac tttatctaca acttgactag ctttgtctct agcctttaat aaaacttctc
    87961 tttgtcgact tgtaagtaag ctatttactt tgtttttaac tctatttaca acgctagatg
    88021 ctctatcttt tgcgtttatg gttgtagata tagttctacc cactcttttt aagttgttgc
    88081 taattctatt tacaacacta gatgttttat cttgagcttg tataactgga ttagctttta
    88141 tcctatttag tgctctcatt ctcttttctg tctgtttcgt gtatctttcc atagcactta
    88201 atttattttt agtttgttca tctcctgtaa catcaatgac aacatcaatg tgatacattt
    88261 cttttttagc tatttctctc acctcacttt tagtttaaat tttatttatt tttcatagct
    88321 ttattttctt gttctatttc atgttgagta aaaactctaa gaagctgttg aggtgttttc
    88381 tctcttttta aaaagtcctc tggaagaata ctatgtttaa catatgcgtt gtataaaata
    88441 gtaatcttcc cacctctctt tattagtttt ttatatcatc atcacttaat tcttcataaa
    88501 atccagacaa ttctagtacc tcatcactaa ttaatgcgat ttctcctgct aagaactttc
    88561 ttcttataaa ttcaacacca ctagatacat tcatagaatt aagaagtctt gcatcgcaaa
    88621 aattaggaac tattgtagct ttttctatta gagctatatt aaattcatct tccattagtt
    88681 tgctttccct tctacctctt accttagtaa cttttgtata ttttttttgc aacgcactta
    88741 tctctttttc tgttaaagcc ctaagtgtaa gtggtatatc taatcttttt acaaaaatag
    88801 ttttttcagg taatatagca tcctctgtca atttcataat tatattatct tcttgttgct
    88861 ttgctatttc ctctttagta agttctcttt cttcttctat tccttcattt aaaaattctt
    88921 tatctaagtt tgccattttt aacttcctcc atttttatag ttttatttga aaagctacat
    88981 ataaaattaa ttacatgtag cttaaattta tttattatgc tattttatcc actagctcat
    89041 aaccctcaaa agtaccatct atttgtattt ctatattttc atcagctttt atacttgcta
    89101 gttgtatttt atctaccata caatttttat atctaattct ttcatatcca actaatccag
    89161 gattttctat ttcagatatt aattcaaatt tatcaaatcc tctttcgatc cattcagatg
    89221 ttgttttaag tacagttaaa gaaaaagtac ctttttgagt agatgccttg ttaagctccc
    89281 atttgcaacc aatcactcta aaggttttct tatcattttc aacctcagct gtaaactctg
    89341 ttccatatcc ttcttctttc ccatcaacta ttattttagc attcgagcca tctgcaacat
    89401 ttgcagcatc tataatattt tcatcatatt ttcccatact ttataacctc ctttatccta
    89461 aatatccagt tccaaagatt ttcttcatca catcaacctt gacagcatcc catttccaat
    89521 aaaactcatc tgctttagca gttgcttgaa gctctgtatc tatatcaaca ttaaattctg
    89581 atataatgcc ttgacccatt aattcttcaa aatatttctt taatgcacat ataacagttg
    89641 tctgccctgt tgaatcatta aatatcttac ctacaaattc ctttcgcttc aatgaagtat
    89701 ctttatttat agtattaata aacataatat tagagatata tcctatagct tcattcttat
    89761 catctacata cttcttaaat gtgtttacat catcaactat aattacgtct ccatcatcaa
    89821 aatcaagtat tagtgtacct gatttcaaac actcttttac ttcactttgg cttaatcttg
    89881 gttctacttc ttcaaatata gtcttagcat tacatatact tcctgttata cctttactta
    89941 cagaaagagc agcaatataa acagctactt cactaggtgt atattttatt ccctcataat
    90001 aagctgaact cccaacatta actatatttt catcattaaa actttttgat ttatcattaa
    90061 tttgttttat attatcctct gcttttccac caagaaataa taatatatct tttcctagct
    90121 ccttattctt agctacccaa gcttttgtag tttcctgcaa tgcttcctca gccacaccat
    90181 caagtacaaa agagtcaaaa ctatatcttt caaattcttc tagtgctttt agataagact
    90241 cattagtaat agatgtgcaa ccatcattcc caccctctaa agcttgattt actacatttg
    90301 ctagaattgt atcgctatca gctactttag ttgcaattac atactcatta tctaaatttg
    90361 agtttatttc tagtactatt tcatctatag tgcctttaat acttgaacta aataactgtt
    90421 tagtattttc aaagaatata aagtcctttt tatctgaatc tactaaattg gattttattg
    90481 ttacattaaa gtttctagct gttggatact tagtttctaa cttaattaca tcttttgcac
    90541 tattttctgt agtatctttt agtgttaatg tacccttctt ttgttttcca tctacaagcc
    90601 tatataataa cagctctttt acatttccta ataaagctaa tttacctaac ttatacgctg
    90661 aatagttcat atcatcacca aacaaagttt taagctgtct caagtcattt tttattgtta
    90721 caaccttgcc aacttctccc caattagcct taactggtat tgctaatcta ccctttaatc
    90781 ctgtgtttgc agacttttct gcttgtgttt tgaatctgtt ataaaagccc ggtatctcct
    90841 ttttttcttt ttcattccat gtaccagttg ccattttact tcacctctct ttctaaaaaa
    90901 tcttttatta atttctcaaa ctctgatttt gtaagttctt ctttcttaca attaaataaa
    90961 gcacctgcaa ctaccatttt ttcgtagcca agtgcttcac tattttttaa gaaatcattt
    91021 ttcaaatatt tttcttcctg cttacttaca ttagtctttt tattaattgt ttcagccaac
    91081 ccttacacct cctattttaa atttccatta ctataaattt tatccataat aggaccttct
    91141 ctttttatct tacctatcat tttgaacaca actgttaatt gtcctgttgt aaacatgtct
    91201 gattccctat cctcaactac gctaacaaga gttaaataca tattcttatc ctctctaagt
    91261 cttactcttt tatctattat taaacttgtt tctaatgctt caagaaactt aactatttca
    91321 tccttatttt tacttacaac atgacatttc atagttttgg taatctcaat caaatgataa
    91381 tttattcttt tgttttcaac atttgtagtt cgccataatg cgcatggagc tataaagttt
    91441 ttcttccaat tttccttata actctcaatt tctaataaat cttttgtata cttagataaa
    91501 gcttcaaccc acctatcatt agttgtatct tctttatctt ctaaagctat tacactaaac
    91561 cttatacctc ttgctatagc atcccattcc tcaacaacaa tatcattttc acttgtacct
    91621 ttataaatgc aagtaaaagc ttcgttttca gattcatcaa ctatagtatt catatctaag
    91681 acttcaacaa cttgtttagt taatttatct aatttcttga atgttgttct gccttcataa
    91741 atccatattt ctatacttct ttcaaagcct attgtttctc cgttgtcatt gtcttgccct
    91801 tgtacaacta ccatataagg ctttttagta tctttgtttg gtacattagg ttcataacaa
    91861 ccttttaatt cttttatatt atctattaac gcttttctta ttcctgctct catttatttg
    91921 ctccaaataa tcaaatacag tcagtatatt tttttattaa ttttacttca ccataatcaa
    91981 ggctaataag ttctactttt ggctttaata tatcgattgg catttttttt gttagtattt
    92041 caaaactttc taaattaaaa tctaaaaaat tattcaaagg tctaatatta gctaaagtat
    92101 atttcaattt taatcactcc aatatctaaa aatcatatta cctattttgc ctatattttt
    92161 atcaatagtt ggttttataa taggcattgc ttttgtacca ggatgttgaa ctgattttac
    92221 aggatgtgaa gcacctctcc agtataaagc ttgagctgat tttggagtaa taacatgtgg
    92281 ttttgaacct tcttcaagta ttcctccata ttctgcacca tgcgataatc taataatgaa
    92341 attatttcct cctccaagag ttttagcatt taaactttgt cttgcatgtg atgttctgtc
    92401 tgtccaactt gcatttgctt tagcttcacc ttctagcatt gcacttgcac tcatacaaag
    92461 tacaaacata cctgcttttt ttctatttat atcatttatt gcatttgtga aagcactcat
    92521 tttaatcaat cctttcaagt gaacattgat acccacaaag ttctcctttt acaatttgag
    92581 gatatacatt aactattttc attctcccat atatgcactc aaactccaaa gaatctctac
    92641 tgttaacatc taagacaaca tcatcactta ctaacattcc atatgttcta atagaactaa
    92701 aagtaccttg cttttcactt gatatttgtt tctctgctgt cttttcatta aatattctaa
    92761 caacacattt tatctctgtt tcagtttctt caaaagctcc atctatttca gtttttttaa
    92821 tattagttat agtaatattg gtagggttca tattaatagt tcttattatg tcttttcttc
    92881 ttctatcaat atttatcata tttcaaattc tgtgctaatt cctaacataa aacttccctt
    92941 ttcttttttg ttagtacaca tatccttgaa tttctctgca ttttgataag ctacagatac
    93001 taggtccttt atactagagc ttttatatgt ttcttgaccc actttatact catacatttc
    93061 ccctactgta ttttcatatt gtaaagattt taatacccat ccttgagaag ctgcacagta
    93121 aatacagtct gcttcttcta aaaacaagtt taattcttca tctgtaaatg attttttatc
    93181 tttatcattt aataatagtc ttaatttttc tattaaatta ctagttggtg tcatatatta
    93241 tcacctcata aaaataacac tcttatgagt gttttatcta aaacttattt cttgtacatt
    93301 ttcttctact gctgcaaaag cacctctata acaatgacct acaatttgat tttctactaa
    93361 cttacttaaa tcagcatttc caacctctgt tgttaaatct ctctttatta actctttaaa
    93421 tcctcgctta ggtcttatca aatatccttt gcctggtgta acacctttgt aagaatatgt
    93481 ttttttacca acagtaacct cccacccatc ataataaatt actgttgata tattttttat
    93541 agatggatac atgcttccgt ttaataaatg tcctccattt aacgccattt ctatttcaat
    93601 ttggtcagca ctagaagcca ttaatatatt accttgtctt tttgctataa ctgtatcttt
    93661 ttgtgcttgt gttaatgttc tccaaattcc tagccatatt gggtcattag tttcaccttt
    93721 aaaagctgtc ttattagaag ctttataatt aaaatttatt attgggctta gatgtatgtg
    93781 gtttaacaag gcattgtaac tctcaccaat tgatttattt aatatttcaa cactaaatgt
    93841 ttggttaaaa tccttcattt cttttgtata ctcaaaacca gttgcataag tttgtatcct
    93901 tgcaactgga ccattttctg catttattgt accgaattta atttcttcac cttctatatg
    93961 ctctaggaat acacagttac cttgtaaagc ccacttagca tccataactt gtggtaaatt
    94021 agaatctgct atactgtcat agattggttt atataatagt tgtacttgct ctctgcctag
    94081 ttcaacatct aatacaactt ttcttaataa ctcttttaaa tttgaagtcg agctaaaagt
    94141 catcatttca ccaagtggct tatttaactc caaggtttcc atttctccat ttgatatttt
    94201 ctttgttaca tattccattt caccatttac tataaatggt atatcttctt gtaaagtttc
    94261 ttttcttttt tgttccagca aattttcctg actaattact ttaaatgcca tatatttatc
    94321 actccttttc tattgttgag gtaataatat aaaccaaatt acattattac tgtctttccc
    94381 atctgttact ctaccaacta gcctattact tgcagatgta gtagtaaatt tcttagctgt
    94441 attatcccaa taaatcaatt tccctgcctc aaaagcttct gatgtaacaa tattatccgt
    94501 ttcgtattca gcttgctcta tttgcaaagt aacttcatcg cctttttctc cgtcttgcat
    94561 agcgactcca aagaatccat ttataagata aaattgttgt gttttagtgc tttcgccttc
    94621 tgaaagaata actcttacag atttcccatc acttattttt gctcttgtta tctgtgttat
    94681 tgtgcttggc gttggttgac ctttaaatgc catataaaca tcactccttt atattctatt
    94741 tttcttagtt gttaaacttc cattattgct agagtttaat aatcctgttg ttgttggatt
    94801 atctttatac atattagaca ttgtattttt tacaaactca tcatttaata tattttctat
    94861 ttctcctgtt attacttctt cacttgagcc ttcctcaaca tttaacattt tcttaactaa
    94921 tgtttgagct atttcacctg acactttatc tttaattact ttattaacta tacagttcca
    94981 agcttccttt ttctcatttt ctaaagcttt tgaagccttt tttgccactt caactgtgtc
    95041 catctctcct actattccaa gtactttttt cacttctctt aattcttttt ctgcttttaa
    95101 tgaacttttt acatcttcca tctctcctgt cacaatttcc ttagttaagc ctattccttg
    95161 tatgacctct gaatatgata tttcaccagt ttgcagtaat cctttgacat tttttattaa
    95221 ctcttttcct tccaatttgt tttcctctcc tttcatttct cctttagctt catagcttat
    95281 tttctttatt acttcaattt cttcacctag atttatttta ttttcaacta tagtaaatgg
    95341 tatactataa agcttgcata atccattttg ctccaactca tatatgacag tattgttatc
    95401 atatcttatg ttttgtatat agagatatga attattatca ttaatagaaa acttagcttt
    95461 taaagcttct cttaaatcta ttcttaaagc ttcaaaagtt ccatctaact gttcgccatt
    95521 aggactcatt tccataccta caatacttgt tggcatacct ggtctatgta gaggagtcca
    95581 atcaatagat agtggctcat atcctataac attcatttcg cctttagcac tctttttaag
    95641 ttttggataa ccaaatatac taacttcttt tatcctttta gttctaatcc atctttttaa
    95701 atttgttgca tcagcatcaa tcagccctct gaaataagct ttatcccctt tcatttctgc
    95761 acctatccaa tgcgttacag gtagtgcaaa ttcagttgat atattttcag ctttttgatg
    95821 tcctaaaaag ccattaagag tattttcatt agtgtaatct acaatatctt tcaagctttt
    95881 agcagtataa ttccatcccc ttttagattt tgtagctggt atctcaacaa ctacctcaag
    95941 agggtcatca tctatagatt ttaaagcttc tatgtctata tctttagcta aaggaatatc
    96001 agaaggtttt atactagata ttaacgcatt cattgagtcc atttctccag ttattacatt
    96061 catttaatca ccacctttca atttaaaaat tcaaatttcc atacacctct tgataccaca
    96121 tttcaagagg tacatcattc ataggatttt taatccaatt tttcaacctt ccaactaata
    96181 tatctaatgg ttgaactaca gtaagcataa tacacaaaca atgagggtgg aatggatata
    96241 caggagcttc atttatagga taaacacctt tacccaaacc aaaattatcc tctccacata
    96301 tttcgtcaca tatatctgtg tgaggatgtg ccatggacaa cataaactga atacctatgg
    96361 ttgcagggtt aatcattgca gaagctaaaa ccccatcacc ataagctgat gtcatttcag
    96421 ttcttgccaa tcttaaagct tcataactta tattttgagg tactctattt cctattcttt
    96481 ttatcatatt tggatattca tcaactaaag ttttcttacc ttttaaaaca tatttgtcta
    96541 acatcttagc tgttttaaca cagtcttgac cttctgttac tgctgtttgt aatataactt
    96601 tcatatcttc tctgtacttc ttacacttag accaaattct atcagataaa aataaaccat
    96661 ccttaaccct tgtataataa gcttctacag ttcttatatt aatatcatag aaagcttttt
    96721 gtatcatagt tttagttact ttagttattt gagctgtctc aactgcatta attaaaatat
    96781 ttttagagta actagtagct gtttcaacat ttttatttaa gtattcatca aaattaaata
    96841 ctagttgttc atttaatatt tttatttctt gcgttaattg ttttagtatc tgttttaacc
    96901 taactttgtt aaagtctgaa agatttcctt ttcttatttc ttttgtaata tttcttgtta
    96961 tgttaatata cattgttctt atttcatcat cttgcttgag ccttaaatct ataaattttt
    97021 ttctagcttc taatgcccat ttcttgtact cccctgcaac agttattaat tccgaagtac
    97081 ttttatccat tgccattatt atcctttatt ttatttattt ccttctcaat ttcatttgac
    97141 tcatcattta aaccttgaga gtcatctaat ctgtatttta acatcttggt ttttattatc
    97201 ttttctcttt ctccaactat ttcagggtca tcacttatat aattgctcat tgtatctata
    97261 tactgtgcta aaaagtttac tgttgattct tcactaataa atccaccctc taaagcttta
    97321 tctaatgcac tacatacttt ttctagtgtt tcagctaatt ctttatcatc tcgtggattt
    97381 acttcatccc aacctatagt cacatcataa gatgaatatt tcataccact agaattagaa
    97441 ctcattatta aaaccattct tgcaagtaat tgccagctat ttgtaaattg ttctcttttt
    97501 cttcttatct tatttaccat aataggcatt tgttctttta cagaagctaa agcactaggt
    97561 gtatgtactc caaatataaa ctcgggtgtt tcagatacat ctactatgca ataaaaaaga
    97621 agctttaaaa gctccttagc atcacctatg gctgatttta cttctacaaa ctcagcttct
    97681 tcatctttgt ttaagaatag tatttcatgc ccatcaagat ttatctttcc accttctttg
    97741 gcaaatttaa ctgggtcttc aacaccaaaa ttgtgtgcta aaaaacttgc aacatcagtt
    97801 aatttcaact ttagttttgg agtagagtgc attttgctac cttttaacgc atgtaacata
    97861 acatcatgat aagcttttaa aagaggttct attggttcta tatcactttg cccatatttc
    97921 aatgtttcat cagcttcatt tttaaaatgt attattggta taaaacccca tacattaggc
    97981 gtttcccctt cttctaaacc ttctatctta tcaccttcaa cctcaacaaa tctactttca
    98041 gcagttatta tttgttttac cttagccttt ctcttgtttt ctcctaagtc agtccattca
    98101 ttttgacttt ctaatatata agctataggc tcttttgttg tagggtctaa tattatttct
    98161 ttcacttctt cgggtgatat gaagttatat attaatctaa cttttttatc gggatataaa
    98221 ggattttctc tttcttctct agttatccaa atataacaat caccttgctt taaactatct
    98281 gtatgtgttt ttaacatttt agatgtgtta tctaaaacaa attcatctaa tatatattga
    98341 gcttcttcat cttctatttg aaaatgaggt acacccataa aaccagttgt tgaattgaca
    98401 atcggtctaa caaaactaga acctagcttg tacttagcat ttttattttg atacagttct
    98461 cttgctaact cataatcaac tctagaatcg tctaatttat atacgccaat gtttccacta
    98521 gacatacgca taatctctcc tgcaggtctt ttaaatagct tttttacata agatattatc
    98581 cccatacact accccctttc agtaaagata aatcagtatt gttattttct gcaaacgaat
    98641 atattactgc atcagctcta tcgggtgatt ctccaattct ttttttcatt tcctttttac
    98701 tttctatttg tattttccct tttgaatcta ctgtatattt tctatttgat agttgtttaa
    98761 taagtttatc atcattagga agctgtatta tagcttcttt attttgtata aaactactta
    98821 aatttgcatc taattcctcc ctcatgttat cccacatttc agaagcttta ttatagtact
    98881 tatctttttc tatagcacta gaaccatttt gaataggtat aacttcatat ttaagtcttt
    98941 catgtcttat aacttctttt aatctatctg ttacacctgc acctaagcca tcatcatccg
    99001 tttttatttt tactctgtta atttgatgat acatattttt aaatttatca actgctctta
    99061 atatatttcc tactgtttcc attgtatctt tttttgaata agttaataaa tcaaatactt
    99121 tcccacctat tcttggagct attatggttt catcatcacc atatcttgct atatccgccc
    99181 ctatatttaa tatatagtca ttagatatat tcacttctct tattgtgctt gtttcaacag
    99241 cttctaaaga tattaaagaa tcactttcac cttttggaaa ctctccaagt actctgacac
    99301 gccaagggtc agaaccttca tggtactttc tttttagcat ttcaatatta tcttttgatg
    99361 ttctagggct gtctaaagaa gatactttaa atgttttata taaatctctg tctctattat
    99421 ggctatcgta aaacgttcca ctcgttctag ttgggtttcc gcataaaaga agcttatttt
    99481 ctgcacctga taatgttccc aatatagctt ccataatggg gtcagcaact cccgaagctt
    99541 catcaacaac aaataacata taatcttcat gaaaaccttg catattctcg ggctttactg
    99601 ctgttctagc tgtagcccac catctttctt caaagccttt catatacact tttgttttag
    99661 tccactcaag tagcttctca accttgctat tacttagcca tttagctatt tcagcccata
    99721 gtacgtcata taattgttgt cgtgttggag ctgtagcaac tactttcgga aaaggtctag
    99781 tgcttaaata ccatacagtt gcaatgcttt ctaatccagt tttacctact ccttgaccac
    99841 ttctaataga tacttttggg gtttgagcta aagccatcag aacatcagat tgccacttgt
    99901 cagctttaaa atttaacata tcctctgcaa accaaacagg attatcccaa taacaatcta
    99961 atagtgtcaa taaagcttta tccattgtta acaccacgtt tcattgcaat attttgtata
   100021 gcttcaaccc aaatttttga atcatctcca gtatcacttt tctttaggtt atcaacttca
   100081 cattttaact tttcaactct a
//
LOCUS       DAEORM030000009        92038 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.009, whole genome shotgun sequence.
ACCESSION   DAEORM030000009 DAEORM030000000
VERSION     DAEORM030000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 92038)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 92038)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 92038)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..92038
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.009"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            468..842
                     /locus_tag="KRH23_000924"
     CDS             468..842
                     /locus_tag="KRH23_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HHS5224214.1"
                     /translation="MIRKIPQAELKVMKFIWKVDVTVTSKDVIEAMEQKYGWKQTTTL
                     TLLSRLVKRGFLDAQKIDRYTHYTIRVKHKDYLSFETKDFLSNIHDDSLRSLISALHD
                     DENIGKDKLDFLESYFDNLKDE"
     gene            835..1869
                     /locus_tag="KRH23_000925"
     CDS             835..1869
                     /locus_tag="KRH23_000925"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M56 family metallopeptidase"
                     /protein_id="HHS5224215.1"
                     /translation="MNNYMLYVFENLIKTTIVCSLGICLLLFLKRYLFKKFSKRFNYY
                     IWLIIVFRMLLFLFNYTIVYEVKEPKENAVGNNITQIDISTDNNLMLYIAYLWLFVTI
                     VIAVYTFIKYTRFKNLVVDVSYDIEDNDINCIYKNLLKELNIKKKIELRGSDELISPA
                     GMGLFKSYIFLPDYPYSKDELTWILKHELMHFKNKDILIKFLVLSVRIIYWFNPLVYV
                     MSNKVNLDCELCCDESVLIDCSLKNKKEYALALIKSIKLSKNYNSGILTTEFNKTSLE
                     KRLDSIVKKKGKSGILVLLILITLFSVTYFNFESISFDNSNSLRNMGILQKSGVDLKE
                     EDDISMRVID"
     gene            1927..2514
                     /locus_tag="KRH23_000926"
     CDS             1927..2514
                     /locus_tag="KRH23_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042834 - peptidoglycan binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan-binding domain-containing protein"
                     /protein_id="HHS5224216.1"
                     /translation="MKNLKKILIITGCLTLISTSLVFANTTTDVDTSKDDDSIISSCT
                     ITGYEFTYENAPQSVKFDYEKKCEALNIKPSKNDIIFVNKDSIDANDVENYVEPKAYI
                     IRYKKGYVFEVTGPKSYTLNVSNTVVGYNRVESGNPVHLVQLLCRTLDGSSIDDDSEF
                     GPATYNAVKSLQGRLGLTRDGIVGRSTWDAAGRRL"
     gene            complement(3164..3709)
                     /locus_tag="KRH23_000927"
                     /pseudo
     CDS             complement(3164..3709)
                     /locus_tag="KRH23_000927"
                     /inference="COORDINATES: protein motif:HMM:NF013068.6"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(3685..3807)
                     /locus_tag="KRH23_000928"
     CDS             complement(3685..3807)
                     /locus_tag="KRH23_000928"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224217.1"
                     /translation="MLESELYELLGYDRMIIRTKILKTLEMDIEIKILNQILEK"
     gene            4415..4792
                     /locus_tag="KRH23_000929"
     CDS             4415..4792
                     /locus_tag="KRH23_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HHS5224218.1"
                     /translation="MMIRKIPQAELKVMKFIWKVDATVTSKDVIEVMEQKYGWKQTTT
                     LTLLSRLVKRGFLDAQKIDRYTHYTVIVKHKDYLSFETKDFLSNIHDDSLKSLISALH
                     DDENIGKDTLDFLESYFDNLKNE"
     gene            4785..5819
                     /locus_tag="KRH23_000930"
     CDS             4785..5819
                     /locus_tag="KRH23_000930"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M56 family metallopeptidase"
                     /protein_id="HHS5224219.1"
                     /translation="MNNYMLYVFDNLIKTTIVCSFGICLLLFLKRYFFKRFSKRFNYY
                     IWLVIVFRMLLFLFNYTVMYEVKEPKENTVGNNITQIDVSIDNDFMLYLVYLWLFVTI
                     AIAVYTFIEYTKFKNLVVDVSYDIEDNDVNCIYKNLLKELDIKKKIELRGSDELISPA
                     GMGLFKSYIFLPDYTYSKDELTWILKHELMHFKNKDILIKFLVLSVKIMYWFNPLVYI
                     MSNKVNLDCELCCDESVLTDCSLKDKKEYALALIKSIKLSKNYNSGILTTEFNKTNLE
                     KRLDSIIKKKGKSGILMLLILFTLFSVTYFNFESISFDNSNSLRNIGILEKTGVDLKE
                     EDDISMRVVN"
     gene            5870..6472
                     /locus_tag="KRH23_000931"
     CDS             5870..6472
                     /locus_tag="KRH23_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042834 - peptidoglycan binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan-binding domain-containing protein"
                     /protein_id="HHS5224220.1"
                     /translation="MKSLKKILIVTGCLTLISTSLVFANTNNDVNVSKSNEEQTTNSF
                     TITGYEFTYENAPQPIKSDYEKKCKELNINPSKDDTIFINEKFIDSYNINIDDYNIEP
                     KAFIIRYKKDLNRFDVTGPISYSVNINTTVVGYGHVEKGNPVHLVQLLCQQINGSDID
                     PDSKFGPATYNQVKILQGRLGVTKDGVVGKATWQAAGERY"
     gene            complement(6557..7579)
                     /locus_tag="KRH23_000932"
     CDS             complement(6557..7579)
                     /locus_tag="KRH23_000932"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HHS5224221.1"
                     /translation="MNYNDLLKSARENFNGTCKVCKICNGLACAGDVPGMGGKGSGSS
                     FIENRKSLEKIKINMRVIHNVSKPDTSIELFGRKMSSPIFAAPVSGTILNMGGKVSEK
                     EYIEPVVRGCSNSGIYAMVGDTNVDTFLLDNLDVLKDNRGNGIVFIKPWNNSKIIDKI
                     RLSEEAGAFAVGVDLDACGLINNQFQENPFSPKTIDEIRELVESTRLPFIIKGIMTVD
                     DALMAVEFGASAIIVSNHGGRVLDYTPGTCEVLPDIAKSVKGKITILVDGGVRTGVDV
                     VKMLGLGADAVLMGRPFVTASFGGGLDGVEFFIEKVRNELCETMILTGCQNVKDIDGR
                     VIWNLL"
     gene            complement(7908..8090)
                     /locus_tag="KRH23_000933"
     CDS             complement(7908..8090)
                     /locus_tag="KRH23_000933"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224222.1"
                     /translation="MYKDKSDECIHLMTAYIDSISGYYSFIDTQLEDFIIKYGENIVD
                     SNLHSIMMLLCKWGLS"
     gene            8403..8822
                     /locus_tag="KRH23_000934"
     CDS             8403..8822
                     /locus_tag="KRH23_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3785 domain-containing protein"
                     /protein_id="HHS5224223.1"
                     /translation="MSLYKFIYDDKEYLLKEENCSALINDEENPVQGVSISKIIDILN
                     EAEEVDFDVEYYQEACPLCLEGVKEKKKFFPFLEYHFYIFSKDGEYVISNISVNYKGL
                     SFNKLSRANKVDNSYIVSVIICENCQDYIIQIENCIV"
     gene            8953..10794
                     /locus_tag="KRH23_000935"
     CDS             8953..10794
                     /locus_tag="KRH23_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0052621 - diguanylate cyclase activity
                     [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HHS5224224.1"
                     /translation="MEDIDDTILDSMFKLTLNERLLTNNDFIENKIDVVKNLIDCYKT
                     EQNSLMLLKSNFLLALLYGIQGFSEKMKEYILISCKYIDKCLPKDYKFLARFYSQMAI
                     LSLKNEDVNKANLYMDKFNLICDENNFLIEEIIFKSQLIYIKASKCIESSVIIKEIET
                     LYIKIKEINDFNCKKIYFFIIGKIYFLFLDDALIAKVNFLKARKYADLLKDIQVSSLC
                     NIKIGECECSFENYECSMEYFNEVISNKKYRNVNIIQKYRASNNITKILIKTRNYPVA
                     INNLAKSEVYLEKIKNHNLKEAEKFDLFISLAMYYAKSNEKSFEQSICYLDRAKNILN
                     MIKNIEEYTIYDLEIIYHQAKIYYIFGYYDNALNTNKKLLEKSKNAKNYNYVKLAYKS
                     IYLCFEKIQNYEMSMKYFKMYYELKMMYIKARNRNYIDSLNYRHEYIEKEINNMRKVK
                     LDLDKKKYVDHLTSAYNRTFLNDFLEKQEVSEYCTAFMIDVDYFKEYNDTYGHYNGDI
                     ALKNITIIIKKYLKKDMLMIRYGGEEFLILSVCKDYKKSKIFGRKLCRIVKKFLNNNL
                     TVSIGIDTCKNSSIDIREIIENADKALYKAKESGRNRCLHYHDFKNF"
     gene            10878..12707
                     /locus_tag="KRH23_000936"
     CDS             10878..12707
                     /locus_tag="KRH23_000936"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0052621 - diguanylate cyclase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HHS5224225.1"
                     /translation="MLTKFYLNLTDLNYILDYHKDLLNTKLEDNSRVYTLYLISLINY
                     IKKDREASYNYLIESLKYIKKLSLKDNADIISKIYIYLTLSAISIRKYDKANNFYFSA
                     KKIIRQNHLNELLVLLNMSLCVEISALYQTKTDVIALVEEVSFFKTLKNKALVSRANY
                     IFGRVYLYLFNNFIKSMEYLIECLRLAQENNLYSIEAFCKCIISLCYLESGNNVEAIK
                     YINNVLDVAHSNNSISVTERVSIKIDLIWAYLKEDMNKEAEVILLKTIKLMKVVEGVY
                     KDYLYSFIFLYSAEIELKKDNCSFEKVNTYLILSKNIYKSFGDVFIYNSKLDYIYKLY
                     GDLYIKFGNIDEGISCYIKGLNLVKKSSLNLRKISIFYGLIANGYELKKDFKLAIEYY
                     KSMDWYSDRWEKNNSYKTSQAIHKQYELRQKQESLRLLVDDNKKLENDILKDGLTKLY
                     NRRYLEQQLDLFNETRDKNMVAILVDIDCFKSYNDNYGHLAGDKVIVKVTDIIRSVFI
                     DITEHIIRYGGEEILILVDSIESIGVEEIDNIELYIKRVFKLLEFEGIEHIYSKIKNY
                     ITISAGVSIKRCRSRKDVEILIEDADKNLYKSKKAGRNQYIII"
     gene            12715..14715
                     /locus_tag="KRH23_000937"
     CDS             12715..14715
                     /locus_tag="KRH23_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HHS5224226.1"
                     /translation="MILLRKKIGIIASDIELKERIEELYREDVENGTIIIDILNLDLM
                     ENQGRILVEKGAQAIIGRGGGYSLVIDTVNVPVIPMNMKSTDLLRAIEIAKKYSKKVV
                     LILGDNEVSFDYVGWRNVISTEITEEWFESKYEIRSKVVKYIDQKDEVVIVGGGLACS
                     FARQYGIDSVFATASDESIREAVEYCKKLLDTLGEEKFNNEVLRNILDGIKDGVIAID
                     SNGSIILYNESAKNMLKVERKCALNKYILDVFPKMEWMLDCLHEKEDVEDRKIRNINN
                     LIVNTRTTLIKVDNSTYGVLGIIQDITKLQNLERKIRFDLNQKGLYARYTFDDFLFKD
                     KLTKEFIEEAKKIGKSDYTTLLYGESGSGKEIIAHSIHNISKRKDRPFVAINCATIAE
                     NLLESELFGYEEGAFTGARKGGKRGLFELAHGGTLFLDEINSLSFNIQTKLLRVIEER
                     QIMRIGSDYIIPLDIRIIAATNESLTEKIVMGTFRADLFYRLSSLEINIPPLRDRRED
                     IIPLFNNFVNEVLKDDGLNGINSIDENFVLTKDEMDKLYNYSWPGNVRELKTIAQKYV
                     VTGKIKLRQDRDFKTKKLLPNSEVDKFNSETTASVEVQDESINISKINDGKISIDIKE
                     VNKYVEEKIISMLFAQGLSKNEVAQVLGISRTSLWKKYNKNI"
     gene            14977..16236
                     /locus_tag="KRH23_000938"
     CDS             14977..16236
                     /locus_tag="KRH23_000938"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008483 - transaminase activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HHS5224227.1"
                     /translation="MSQSMVGKHAMWPKENDVIFSISGRAQAAEKAFGMDNVINATIG
                     ALMDDSGKLITMKTVYEEYKALDNCEIGAYAALEGQPDYLEAVKKVFFRDYLPEGHIR
                     VLASPGGSGAIKLAVWNYTNEGDEVLTSDWFWSPYVSIAEEANRKVVNYQLFDENRRF
                     NFESFKEKFVNIAEKQGRVFTIINTPAHNPTGYSVADDEWDKILDLSKEVAKDKDKKI
                     IFFVDSAYIDFAGDDDVCRKFFKKFSNLPENVLVLVGFSMSKGFTAYGMRMGAIICIS
                     SSEDVAEEFHYSCVHSCRANWSNCNRSAMAVLSNIVNDPKKFKEYEDEKEIYKNMLTR
                     RADVFVKEAERVGLEILPYIAGFFVSIPCDNPKEVCEELTKHNLFAVPLKMGLRFAVC
                     AVSEDKCKKAPSIIKEALESLEVKINN"
     gene            16297..18084
                     /gene="iorA"
                     /locus_tag="KRH23_000939"
     CDS             16297..18084
                     /gene="iorA"
                     /locus_tag="KRH23_000939"
                     /EC_number="1.2.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043805 - indolepyruvate ferredoxin
                     oxidoreductase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="indolepyruvate ferredoxin oxidoreductase subunit
                     alpha"
                     /protein_id="HHS5224228.1"
                     /translation="MKQLMTGNEAIARGAYEAGVKYASAYPGTPSTEILENIATYKDA
                     IVAEWAPNEKVALEAAIGGSIAGARTMASMKHVGLNVAADPIFTYAYTGVNGGMVLIT
                     ADEPGMHSSQNEQDNRMYAKFAKIPLFEPSTSQEAKDMIKEAFEVSEKYDTPVLYRVT
                     TRLCHSKGLVECYDREEVEIKEYVKNAKKMVTVPANAQIRRGVVEERMEILKKFSNET
                     DLNYYEINDTKIGVIASGMCCNFAKEVFGKNASYMKLGFTNPLPYEKIKEFAEKVDKI
                     YVIEENDPFIEEQIKAYGIDCIGKDVIPPYGEMTPDVLRKAIFGKTNDTIEYKSELVT
                     PRPPSFCAGCPHRGFFYELGKRKNLIVGGDIGCYTLGFAPPYNGIDYVVCMGSAFGTA
                     HGAQKVLNMKDDNEKRLVGVLGDSTFFHTGINGLLDVVYNRGNSISVILDNRITGMTG
                     HQENPGSGYTLQGAKTKEVDIEGLVKACGIEHVRVINPNNLKEVNEALDWALAIEDEP
                     SVIITRWPCVLKKFSKEDIEEFNNPFKTKCKVDHDKCIGCKLCLKTGCPALSFDKENK
                     LSNIDRNQCVGCGVCAQVCPKQAIVKEEK"
     gene            18086..18661
                     /locus_tag="KRH23_000940"
     CDS             18086..18661
                     /locus_tag="KRH23_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indolepyruvate oxidoreductase subunit beta"
                     /protein_id="HHS5224229.1"
                     /translation="MTKSILLVGVGGQGTILASKLLTMGLMEAGYDVKMSEIHGMSQR
                     GGSVSSQVRYGDCVHSPVIEIGGADILVSFEKMEALRWFNYLKPEGKALVNNHRIDSM
                     TVLIGGAEYQESDIDAELSRLNAKVINAADKAEELGNSKIMNVILLGCLVKSMQLESI
                     DWEKIISENVKPKFVELNIKAFHEGMEMVSK"
     gene            18714..19784
                     /gene="buk"
                     /locus_tag="KRH23_000941"
     CDS             18714..19784
                     /gene="buk"
                     /locus_tag="KRH23_000941"
                     /EC_number="2.7.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0047761 - butyrate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006113 - fermentation [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="butyrate kinase"
                     /protein_id="HHS5224230.1"
                     /translation="MTYRILAINPGSTSTKIAVYDGEEQILVKTIDHPAEEIAKYNTI
                     QDQFEMRKEAVLNILKENSIDLKSLSAIVGRGGVLPPVKSGAYLVNEEMIDVLRHRPV
                     LEHASNLGAVVAHAISEPLGINSYIYDSVAVDELIDVARISGLCGMDRSSAGHALNTR
                     AMALKYAKDKGKDYKSLNLIVAHIGGGVSIYLHEKGRMVDMLSDDEGPFSPERSGRVP
                     ATKLVAACYSGQYSEREMTKKIRGKGGIVSYLNTVDAREVEKMIAEGNEEAKIIYEAM
                     AYQLAKGIGELATVVDGKVDAIIITGGIAYSEMFTSMVKKKVEFIAPVEIMAGENELE
                     SLAFGTLRVLNGEEEARIYSEN"
     gene            20002..20703
                     /locus_tag="KRH23_000942"
     CDS             20002..20703
                     /locus_tag="KRH23_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YczE/YyaS/YitT family protein"
                     /protein_id="HHS5224231.1"
                     /translation="MGKISLKSMIRLFSGFFIFAISSVLMINAHVGLMPWDVLHQGLS
                     IKLGITIGQASIMVGVVIVILDAVFGENIGWGTLLNMTFIGIFIDLVIFSGVIPHASN
                     TYIGVFMVVIGIILAAIASFLYLGVCLGSGPRDGLMIALQKKTNKSVRLVRTILEILA
                     LVVGWLLGGSVGIGTLVSALGLGYVLQIVFRIFKFDTKLLKHRFIIDDIREWKEKKSN
                     EHKCKSSIVIKNEQN"
     gene            20763..21269
                     /locus_tag="KRH23_000943"
     CDS             20763..21269
                     /locus_tag="KRH23_000943"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016817 - hydrolase activity, acting on
                     acid anhydrides [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0009132 - nucleoside diphosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HHS5224232.1"
                     /translation="MELWDLYNADGIKTGNVIKRGNSIEEGYYHLAVEVWILNSNSQI
                     LIQKRSKSKKTLPNMWGMTTGCIVSGEDSLEGAIREAKEEIGIDITKDEMKVFRSMIH
                     EDTLWDVYLVKKEYDISKAILQEEEVSDIKWVSTDEIRQLLKEGLFFEYPEIYELLYE
                     IDNNKLNI"
     gene            21444..22466
                     /locus_tag="KRH23_000944"
     CDS             21444..22466
                     /locus_tag="KRH23_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HHS5224233.1"
                     /translation="MEDNKGLARDSSKYKIVSISVVVIILITFWYMLNMVLLTFIMTF
                     IFYNLLVATRKRIKKFSSLNIPDSLIIIVLYALFAILLVLISYAVVPIIIVQLTELSR
                     VFSDFDVNQFAQSLGPKLYPIVSKLDFNKYISQAGLLIASTATKVGSFGVNILLAFLL
                     SLLLLLEKNEIKNFGDKLSDSKISFIYNSLVFFGKSFVKNFGEVMKVQVMIAFINSVV
                     SMIFLGFMGFPQIWALGFMIFVLGLIPVAGVIVSLIPLTVIAFNTGGITKVFGVLLMI
                     CIVHAVETYILNPKLMSNRTKLPVCFVFIILLVGEHYLGVWGLLIGVPIFMFLMDILG
                     VKFTSR"
     gene            complement(22613..22921)
                     /locus_tag="KRH23_000945"
     CDS             complement(22613..22921)
                     /locus_tag="KRH23_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1540 domain-containing protein"
                     /protein_id="HHS5224234.1"
                     /translation="MKNNNLNCAATNCAYNTSGYCYAGSIKVDGMQATTTENTYCASF
                     EDKYTSGITSRSNETNQVDTDNIHCEAVKCKYNKNELCKAEKVHINERNASCETFEMK
                     "
     gene            complement(22981..23409)
                     /locus_tag="KRH23_000946"
     CDS             complement(22981..23409)
                     /locus_tag="KRH23_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224235.1"
                     /translation="MNNKLHELEKNLPETSCSFCTHLSFKGPSLDYRYDIRCVISDTK
                     PDFRGCCEYFEPEYTELNTGDLDNLYINFLETCLKVNYNDYINSMYWKLFKERTLLEN
                     NFKCSICGSTENVDVYHVNKNLGRETSKDVVVKCDKCNCK"
     gene            complement(23632..25089)
                     /locus_tag="KRH23_000947"
     CDS             complement(23632..25089)
                     /locus_tag="KRH23_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_process: GO:0015833 - peptide transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbon starvation CstA family protein"
                     /protein_id="HHS5224236.1"
                     /translation="MTTFLIGLAILLIGGALYGAYCEKVFGPDDRKTPALAQSDGVDY
                     VPMKKWKNSLIELLNIAGTGPILGPIQGILFGPIAFILIPIGCVFGGALHDYMSGMIS
                     IREKGAQMPSLISRFLGNKVFQVYNIFLCLLMLLVGAVFIYTPGDLVVTQILNMKSTI
                     NNPVVWIVYGLIFLYYLCATLFPIDKIIGKVYPIFGAILLLSAAGVGIGIFTQGYDLA
                     NLSLANWKGIHPDGIPLIPTFFVTVACGIVSGFHSTQATLIARSVSNEKEGKTTFYNM
                     MILEGLIAMIWAAAAMGIYNKGIPKELVGSPDVIGLVARDLLGSIGGIIAIIGVIVLP
                     ITSGDTALRSLRLMLADYFHYDQKEKKHRVILSICIFIPVIAILIFAKLSASGFNILW
                     RYFSWSNQTIAIFAFAMITVYLIIKEKNYIISLIPGMFYSFVIFSYIFNAQIGFNLNI
                     NISYVLAAIFTVLYAILTVRSGRKLKSKADTKLAD"
     gene            25507..26421
                     /gene="nadA"
                     /locus_tag="KRH23_000948"
     CDS             25507..26421
                     /gene="nadA"
                     /locus_tag="KRH23_000948"
                     /EC_number="2.5.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008987 - quinolinate synthetase A
                     activity [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="quinolinate synthase NadA"
                     /protein_id="HHS5224237.1"
                     /translation="MDKDLTYQIKELKKEKNAIILAHFYQPPEIQELADAVGDSYYLS
                     EIARDCKEEVVVFCGVRFMGESAKILSPEKTVLMPVSNAGCAMADMVDEEGVIKLKQQ
                     YPNALVVCYINSTAKVKAHCDVSVTSSSAIKILENIDNKEIIFLPDKNLGGYIAEQFP
                     DKNFIFWDGYCKYHNNIRAEEIIELKDKYKNAEVLVHPECKKEIRDLGDYVGSTSGII
                     KYATNSKNKDFIIATEEGILHELKKNNPNKNFYIPGGKILCTDMKKTTLENLYSTLKN
                     MENEVIVEDEIMEKALNSLLNMHKLAEG"
     gene            26434..27735
                     /locus_tag="KRH23_000949"
     CDS             26434..27735
                     /locus_tag="KRH23_000949"
                     /EC_number="1.4.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008734 - L-aspartate oxidase activity
                     [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-aspartate oxidase"
                     /protein_id="HHS5224238.1"
                     /translation="MNLEQDVLIVGSGVSGLYCALNLDKSLNVLVVSKSTIENNNTYL
                     AQGGISTARNIDDIESFVEDTMKAGQYKNRVEAVQVLADESIENVGQIVEYGMPLDKE
                     NGEIDYTREGAHSVNRIVHSKDNTGEVVFKTLLKEAKTRENITLIEDAYLLDILKDGN
                     KCIGARIFKSKKEIHVFSKIVVLATGGIGGLFKNSTNQRHLTGDGIAIALRNNIKIEN
                     LEYIQIHPTAFYEENNEGRRMLISESLRGEGAKLLNKNKERFVDELLPRDVVSKAIFE
                     QMEKDKLPYVYLDATHLDSEYLINRFSFIYNECLARGTDITKECIKVSPAQHYFMGGI
                     HVDLDSKTSMENLYAVGEISCTGVHGANRLASNSLLEGLVFSKRAAKNINSVIDNVKV
                     KFIDVPDMDIDIEQVKKENKILVIKEIERTSEDFGDELFDY"
     gene            27716..28552
                     /gene="nadC"
                     /locus_tag="KRH23_000950"
     CDS             27716..28552
                     /gene="nadC"
                     /locus_tag="KRH23_000950"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004514 - nicotinate-nucleotide
                     diphosphorylase (carboxylating) activity [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HHS5224239.1"
                     /translation="MNYLIIDRMIQDALIEDVPSEDITTNSIVDENSKSTVDLICKQD
                     GIIAGLGVFKRVFEILGDVDVKLYKNDGDRVKNREKIAVLTGSTRNLLVGERVALNYL
                     QRMSGIATITSRYVEKLEGTNTKLLDSRKTIPNLRILDKYSVKVGGGCNHRFNLSDGI
                     LLKDNHIGAAGSVKKAVELARKNTSFVRKIEVEVETLDMVKEAIEANADIIMLDNMSL
                     EMAKQAVDIINGRAIVEFSGNVNLDTIEDIGKIGVDVVSVGALTHSVKALDISMKNLR
                     NI"
     gene            28808..29140
                     /gene="saoD"
                     /locus_tag="KRH23_000951"
     CDS             28808..29140
                     /gene="saoD"
                     /locus_tag="KRH23_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0018942 - organometal metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DsrE-related protein SaoD"
                     /protein_id="HHS5224240.1"
                     /translation="MKVAYIFSSTNTHKILDKMIIPQLEQGTHGVDVLGMFFFMDNTL
                     FLSKGNPVGERLSKLHEKTDMIIMACDQCAIERGIENNLVDGATIGCFPNLYACLGSA
                     GVDQVITL"
     gene            29230..29487
                     /gene="saoT"
                     /locus_tag="KRH23_000952"
     CDS             29230..29487
                     /gene="saoT"
                     /locus_tag="KRH23_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_240067706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0018942 - organometal metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_except=(pos:29263..29265,aa:Sec)
                     /transl_table=11
                     /product="thioredoxin-like (seleno)protein SaoT"
                     /protein_id="HHS5224241.1"
                     /translation="MSKILVEFINTUPSCDEHGVFIKKMSEKYADKLEIKLYQAGKDF
                     SYIKKYGIITKGTLIINQKKKYDRLNKDTIERAIVEAINNN"
     gene            29514..30599
                     /gene="saoE"
                     /locus_tag="KRH23_000953"
     CDS             29514..30599
                     /gene="saoE"
                     /locus_tag="KRH23_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0018942 - organometal metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux transporter SaoE"
                     /protein_id="HHS5224242.1"
                     /translation="MNILEIVLNGVKDTIVASIVTLNGASGWLMISFILAGVLHNVLT
                     PRRFQKQLGNKKFSSLIKSTISGMFLPICSCGVIPLGISMYYSGAYLGPVLAFMTSTP
                     IINPIAVVLCLGLLGPKVTIIYLIAGFLVPFLVGFLGNCFGKEELSLHNDSEEEVIEL
                     EEEKRSFMENMIDGLKWSFGELALTISKYVVMGMVFAGFITTIFPNSIIQKYLGNPGL
                     LSLGSIAILACVMYVCAVGHIPFIAALVASGASPGIAITFLIAGAATNLPELISMFKL
                     IGKRTVIIYSVTLTLSSIIIGYITNLLLVNNNSVNLDATNSSIQLANKLMLNIPDSFE
                     YVCTILIILFAFKSIIPKMKEVIGNHA"
     gene            30592..31050
                     /gene="saoC"
                     /locus_tag="KRH23_000954"
     CDS             30592..31050
                     /gene="saoC"
                     /locus_tag="KRH23_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0018942 - organometal metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-Cys-COOH (seleno)protein SaoC"
                     /protein_id="HHS5224243.1"
                     /translation="MLKKIVIISCIVVVLIILSKIVDDNIKEDASIPNVNKETLEYFR
                     KNYKEDIITCAEEDLNNDGKKDLVVIYKKSNNSNEMVVVVSDKNSHYITKPIPAPIEN
                     QTITFKNIDDKAPIEVIVSGSKNGNVGYAIYRVEGKKFVDLFGEDMDKCC"
     gene            31085..32176
                     /gene="saoX"
                     /locus_tag="KRH23_000955"
     CDS             31085..32176
                     /gene="saoX"
                     /locus_tag="KRH23_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0018942 - organometal metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding subunit SaoX"
                     /protein_id="HHS5224244.1"
                     /translation="MKLSKKIQALILFGVMGTSILTGCSSKPKEKEEAKTGKDDYTIT
                     VGYYNCDHMTAGPVAESAGIYKDLGLNVKTVGNGKVPEAMAAGKMDAGYIGTKGLVGA
                     IPKGSPITIAANNHTGGSEYLIVSKDIKEPKDLIGKKIATDMSDFLWTSDYGPETGLP
                     TDPSKYEVVNMDSDKDKYLALKTGKIQAFTSCDPWGSVAENDGAGKIIASTQYKEKAN
                     GKEYNCCSFSLNKNFIKEHPDLAKKLVLAHTKAIEYIYTNPAEAAKIFAKYYNVEEEV
                     ALRTIYKKTVGEGRTLTWKVTGEEYKNNLQMYKDLKALDDIPKYEDTIDTSLLDSCGA
                     DDFDKFIKEKVNPEFPEGMSYEDWKAKVL"
     gene            32190..32978
                     /gene="saoB"
                     /locus_tag="KRH23_000956"
     CDS             32190..32978
                     /gene="saoB"
                     /locus_tag="KRH23_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_239591066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0018942 - organometal metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_except=(pos:32403..32405,aa:Sec)
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     (seleno)protein SaoB"
                     /protein_id="HHS5224245.1"
                     /translation="MKNIIILFIIILGSIFIIFFNFEDKEEIKGKLRIGVSDDTSGFV
                     INYMVNRDYFENIKVSDIMDIFTINDCUASTMQWALSSEEIDIAIICKDAAKQYVNVN
                     SGFEVVGTVVQNSDIFLLSDNNPEKIGVIQNRDYQSELVKKYYKNVEVAPLLGTALTY
                     GLESNLVDGVVIDCIKSIGLEGKRKSTTKLGDYDTYVLVVNKEFKKSKAYSDFITLYN
                     KSVDALKNKATFKKVLKEYRNIRNIDMEEISNWKLKFLKIKAID"
     gene            33002..33745
                     /gene="saoP"
                     /locus_tag="KRH23_000957"
     CDS             33002..33745
                     /gene="saoP"
                     /locus_tag="KRH23_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_239591061.1"
                     /note="Most members of this family are selenoproteins with
                     the selenocysteine residue at the channel-gating position;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0018942 - organometal metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_except=(pos:33566..33568,aa:Sec)
                     /transl_table=11
                     /product="ABC transporter permease subunit SaoP"
                     /protein_id="HHS5224246.1"
                     /translation="MDILYKIILLVIIFLVWHFAAKDIGSSLLLPMPVDVIKGFFFCV
                     TDAETVTNLFITLQRVLKGFMYALLFGLPIGFIMGFSKTFERVLSPVVDSVRQVPIMA
                     WVPLTIVWFGIGDGPTIFLIAFSGVFPIILNTIQGVRAISKDYYNAARSMGASPIVIF
                     TNVIVPASLPDILTGSRIAISTGWMSVIUAEFIATSAGLGYSMVQAQTLMHTDVLIGL
                     MIFAALIGFIIDRVLKFINKILCRWRFAD"
     gene            33745..34497
                     /gene="saoA"
                     /locus_tag="KRH23_000958"
     CDS             33745..34497
                     /gene="saoA"
                     /locus_tag="KRH23_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0018942 - organometal metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein SaoA"
                     /protein_id="HHS5224247.1"
                     /translation="MKLSVRDINKTFVNNRVHTKVLEDISMDIDDGQFVCLLGPSGCG
                     KTTLLTIIGGFQKSERGDVFINDKRVKKPGIDRAFIFQNYALFPWKTIRGNVLFPMKQ
                     QKIPKEKREEMLEELLVMSDLKGKEKLFPHQLSGGMKQRVAMIRALACNPEVLLMDEP
                     LGAVDFQMRQNLQEELERIWIKKKITALMVTHDVDEAVYMSDRVIVMSRDKGRIIDDI
                     NIDIPRPRIRGSQKYEEYKNKLTDTLSKCYEV"
     gene            34510..35151
                     /gene="saoL"
                     /locus_tag="KRH23_000959"
     CDS             34510..35151
                     /gene="saoL"
                     /locus_tag="KRH23_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_238476746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0018942 - organometal metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_except=(pos:34993..34995,aa:Sec)
                     /transl_table=11
                     /product="MerB-like organometallic lyase SaoL"
                     /protein_id="HHS5224248.1"
                     /translation="MSQIEKYNSLDNTQQKIRISIMDMIIDKGSSVTLQEVTEYVSKK
                     LNIEKEYIERTLQYFIYKNIMVVDGNSINFIYPVSALPTNHKVTLRDNRSFSAMCAID
                     AIGTSCTFNQDIKINSICSATGKEIEVIIKNEKIEYVNNPNLRVLHINLDKHLNWAAS
                     CUNIMNFFWTKSDFDAWTNEAGLSDDEDIYCLDINEAIVESYKIFKLKQKVLS"
     gene            complement(35288..36109)
                     /gene="yidA"
                     /locus_tag="KRH23_000960"
     CDS             complement(35288..36109)
                     /gene="yidA"
                     /locus_tag="KRH23_000960"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HHS5224249.1"
                     /translation="MYKLIALDIDGTILNTQKRITPEVFESIQEAKRAGAKVVITTGR
                     PLPGVKELLNQLNLTDEGDYVICFNGAIIQEVKSEKIIHDVEMSLDDFDFIYNNVCKK
                     YKTKIHINTMTNLITPNETPGKYTLHEAKLNNIEVKYIQKDKIDESIKICKIMIVDEP
                     ERLEEIIQQLPKNLFNKYTIVRSAPFYLEFLGKTTNKGTALKTLCMNLNIPIENAIAV
                     GDEENDQHMIKYAGLGVAMGNARNSIKEIADYVTDTNNENGVAKVINKYILNKAI"
     gene            36602..38296
                     /locus_tag="KRH23_000961"
     CDS             36602..38296
                     /locus_tag="KRH23_000961"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family oligoendopeptidase"
                     /protein_id="HHS5224250.1"
                     /translation="MKFSEFKYERPNNNSMKKEFLSCVEDINNSRNYKEQQKNIHKIN
                     LLRNKIETLSNIASIRYSTDTFNKFYKEEKNYWDEYMPLYEELNSYFYNAIVNSKFKY
                     DLIKEFGEQFFTIVEYSLKSFSKEIISELQEENKLCSEYTRLLASAEIMFDGKIRNLS
                     GMGKFMYSKNRKTRELANKAYYNFFEENETKFDDIFDKLVKLRDKMSKKLGFEDFVEL
                     GYVRMMRSDYREYMIKNVRKQVLKYVVPMANELYEKQAKRIGLEYLSYIDEGVEFLTG
                     NASLKGDSRYIIQNGKRMYSELSKETNEFFDFMLENELMDLETKKGKGAGGYCTYIPD
                     YKSPFIFSNFNQTADDIDVLTHEAGHAFQLYMSRWIDMPEINFPTLDSCEIHSMSMEF
                     ITWPWMDLFFKEDTDKYKFTHLSSSIKFIPYGVIVDEFQHYIYKNPNVDKSKRKEIWR
                     FLEKKYLPHRKYGDNSFLERGCWWFKQGHIFKNPFYYIDYVLAQICALQFWKKMIQDR
                     DAGWKDYINICKVGGTKSFLDIVSMGNLYSPFDDGCIESIIGDVKSWFDEINDSKL"
     regulatory      38628..38738
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            38842..39213
                     /locus_tag="KRH23_000962"
     CDS             38842..39213
                     /locus_tag="KRH23_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GrdX family protein"
                     /protein_id="HHS5224251.1"
                     /translation="MIIITNNPKVKEEVQGREVLFKDTTYIGILEASRDLIHEGYELL
                     SHPLYGSVKPNETPYRTVILKKGNRLDINSLTLIEEAIITASKFQNNKKTPKWTESVQ
                     DDFRVIDYDIFYNTIQRMQYE"
     gene            39309..40256
                     /gene="trxB"
                     /locus_tag="KRH23_000963"
     CDS             39309..40256
                     /gene="trxB"
                     /locus_tag="KRH23_000963"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004791 - thioredoxin-disulfide reductase
                     (NADPH) activity [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA];
                     GO_process: GO:0019430 - removal of superoxide radicals
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HHS5224252.1"
                     /translation="MENVYDLVIIGSGPAGLAAGLYGARAKLKTLILEKDKTGGQIVI
                     THEIANYPGSVPNATGPSLIARMVEQCKEFGAEMLRDNIVDTELDGDIKVLKGEKAEY
                     RAKAVIIGTGATPRKIGCPGEKELTGKGVSYCATCDADFFEDFEVFVVGGGDSALEEA
                     MYLTKFARKVTIVHRRQGFRCAKSVEEKAKANPKIEFLLDTVIEEIKGDGILESVVFK
                     NKVTGETHEYFADEEDGTMGVFVFVGLDAQTDLFKGKVDMDEKGYIITDEDMRTNIPG
                     VFAAGDCRSKTLRQVVTATNDGAIASIVAEKYIDEKFGN"
     gene            40360..40677
                     /gene="trxA"
                     /locus_tag="KRH23_000964"
     CDS             40360..40677
                     /gene="trxA"
                     /locus_tag="KRH23_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015035 - protein-disulfide reductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin TrxA"
                     /protein_id="HHS5224253.1"
                     /translation="MLDLDKATFEEEVLNAEGFVFVDFWSEGCEPCKALMPDVHKLAE
                     TYGDKIKFCKMDTTKARRLAIKQKVLGLPTMAIYKDGEKVDEVTKDDATVPNIENMIK
                     KYL"
     gene            40946..42232
                     /locus_tag="KRH23_000965"
     CDS             40946..42232
                     /locus_tag="KRH23_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006439082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine/sarcosine/betaine reductase component B
                     subunit"
                     /protein_id="HHS5224254.1"
                     /translation="MRLELGKIFIKDIQFGDVTEVKDGVLFINKQEMLQEIGGDEHIK
                     SIDIELARPGESVRITPVKDVIEPRVKVEGNGGIFPGIMSKVDTVGEGKTHALKGVAV
                     VTTGKIVGFQEGIIDMTGEGAKYTPFSKLNNVVVIAEPIDGLKQYAHEKAVRMIGFKA
                     AMYLGEVARNLTPDEVSVYETKPLLESIKEYPELPKVGYVYMLQTQGLLHDTYVYGVD
                     AKQIVPTLLYPTELMDGAIVSGNCVSACDKNPSYVHINNGVVEDLYARHGKDINFVGV
                     IITNENVYLADKERSSNWTSKLCKYLGLDAVIVSQEGFGNPDTDLIMNCKKIEMQGVK
                     TVIVTDEYAGRDGGSQSLADADVRADAVVTGGNANQVVVLPKLDKVIGHLEVVDVIAG
                     GSDGSLRADGTIEVEIQAITGATNETGFGHLTAKGY"
     gene            42344..42817
                     /gene="grdA"
                     /locus_tag="KRH23_000966"
     CDS             42344..42817
                     /gene="grdA"
                     /locus_tag="KRH23_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_110943085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030700 - glycine reductase complex
                     [Evidence IEA];
                     GO_function: GO:0030699 - glycine reductase activity
                     [Evidence IEA];
                     GO_function: GO:0050485 - oxidoreductase activity, acting
                     on X-H and Y-H to form an X-Y bond, with a disulfide as
                     acceptor [Evidence IEA]"
                     /codon_start=1
                     /transl_except=(pos:42476..42478,aa:Sec)
                     /transl_table=11
                     /product="glycine/sarcosine/betaine reductase complex
                     selenoprotein A"
                     /protein_id="HHS5224255.1"
                     /translation="MSLLSNKKVLIIGDRDGIPGPAIEECVKTVEGAEVVFSSTECFV
                     UTAAGAMDLENQNRVKDAADKFGAENVVILLGAAEAEAAGLAAETVTAGDPTFAGPLA
                     GVALGLSVYHVVEEPIKSLFDESVYEDQISMMEMVLEVEEIEEEMSGIREEFCKF"
     gene            42849..44159
                     /gene="grdB"
                     /locus_tag="KRH23_000967"
     CDS             42849..44159
                     /gene="grdB"
                     /locus_tag="KRH23_000967"
                     /EC_number="1.21.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030700 - glycine reductase complex
                     [Evidence IEA];
                     GO_function: GO:0030699 - glycine reductase activity
                     [Evidence IEA];
                     GO_function: GO:0050485 - oxidoreductase activity, acting
                     on X-H and Y-H to form an X-Y bond, with a disulfide as
                     acceptor [Evidence IEA]"
                     /codon_start=1
                     /transl_except=(pos:43896..43898,aa:Sec)
                     /transl_table=11
                     /product="glycine reductase complex selenoprotein B"
                     /protein_id="HHS5224256.1"
                     /translation="MGKLKAVHYINQFFAGIGGEEKADTKPHVAETLPPISLQLDKLL
                     GEDIEIVGTVVCGDSYFNENIDSASEEVLSMVKGFEPQLFIAGPAFNAGRYGVAAGTI
                     TKVVKDALNIPALTGMYVENPGADMFKKDVYVVETSDSAAGMRKALPKIAKLAVKLAN
                     GEEIGTPKDEGYIARGIRVNYFHEDRGSKRAVDMLVKKIKGEPFETEYPMPNFDRVDP
                     SKAVKDLSKCKIALVTSGGIVPKGNPDRIESSSASKYGTYSIAGVMDLTEETYETAHG
                     GYDPVYANLDADRVLPVDVLRDLEKEGVIGKLHETFYTTVGNGTSVANSKKYASEIGA
                     ALVADGVDAVILTSTUGTCTRCGATMVKEIEKTGLPVVHMCTVVPISLTVGANRIVPT
                     IAIPHPLGNPALDPTEEKALRRGLVEKALNALTTEVDGQTVFEK"
     gene            44416..45948
                     /gene="grdC"
                     /locus_tag="KRH23_000968"
     CDS             44416..45948
                     /gene="grdC"
                     /locus_tag="KRH23_000968"
                     /EC_number="1.21.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine/sarcosine/betaine reductase complex
                     component C subunit beta"
                     /protein_id="HHS5224257.1"
                     /translation="MTYPVLKGAGYVLIHTPDMIVQNGSTCTVERATNPDSEFLKEVS
                     NHIRSYEDVVNYMPNQVYIGNRRPEELRDLPMPWCEQKIEGTRNGKFGEIMPQDEFIA
                     LMQISDAFDLVKLSQEFIDEVKPKIENNYPEIAPFVGKLKGDDIEEGKELVATHIAEG
                     LYHDGKFVGYVKRAHDVDVNLNAHTMFENLVVKASGVLSAIQMLRHSKIDPAEIDYVI
                     ECSEEACGDINQRGGGNFAKSIAEIAGLQNATGSDTRGFCAAPTHALIQAAALVKAGI
                     HKNVMVVAGGASAKLGMNAKDHVKKGLPVLEDVVGGFAVLVSENDGVNPVIRTDLTGK
                     HTVGTGSSPQAVMTALITSGLDRANLKITDVDVYSVEMQNPDITKPAGAGDVPEANYK
                     MIGALAVKRGDLEKKELKDFVSNKGLPGWAPTQGHIPSGAPYIGFLIDDLTTGNRNRA
                     MIVGKGSLFLGRMTNLFDGVSFIAERNTGVTEETSGISKDEIKKIIAESMKKLALDML
                     EE"
     gene            45959..47104
                     /gene="grdD"
                     /locus_tag="KRH23_000969"
     CDS             45959..47104
                     /gene="grdD"
                     /locus_tag="KRH23_000969"
                     /EC_number="1.21.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine/sarcosine/betaine reductase complex
                     component C subunit alpha"
                     /protein_id="HHS5224258.1"
                     /translation="MSRKVIADVFLEVANAIESGEFGKKVKIGVTTLGSEHGVENMVN
                     GAQLAKSNLFDIVLIGPKVETDLEVVEVNDEKEMHAKMEELLDSGYIDACVTMHYNFP
                     IGVSTVGRVITPAKGKEMILATTTGTSATNRIEAMVRNAIYGIATAKSMGNKCPKVGI
                     LNVDGARQVEKCLKELKDNGYDMEFADSIRADGGCVMRGNDLLVGAPDVMVTDTLSGN
                     IFMKVFSSYTTGGDYEAQGFGYGPGVGEDYDRKVLIVSRASGSPVVANALKYAYDVVK
                     GDISNVARNEFAKVKKAKFDDIISSLTKKEVKVEKVEVKMPDKEIVTRQIAGVDIMDL
                     EDAVSELWKNGIYAESGMGCTGPIVLVNEAKGDLAVETLVKAGYTAK"
     gene            47414..48493
                     /locus_tag="KRH23_000970"
     CDS             47414..48493
                     /locus_tag="KRH23_000970"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004177 - aminopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M24 family metallopeptidase"
                     /protein_id="HHS5224259.1"
                     /translation="MSRVKNVVELLETKGVDALYLTKKTNVNYISGFPDEEAYAVICK
                     DGNFLVTDSRYMELAEKVCKDFEIINWHNFDRSVAKAVKSVCDKVGIKKLGFERTNIV
                     FDKYEELKNLIEKDNGELIPTENIVETLRYVKDKDEIKNTRKACEIADKALEELIPHI
                     KAGVSEIELATKLEYFMKMNGAQNIGFETILISGAKTSLLHGKPSDKIIEKGDFVLID
                     YGAMYNGYISDTTRTFIVGGASEKQLEIYNLVKEAQNVGVENMKAGVHATIPDAEIRK
                     VVKKYEDYYYQGIGHGVGRDVHEEPFIGNYGDKIIEEGCIITMEPGIYFPGWGGVRIE
                     DTVLITKNGPERLTKFPKDLMILDK"
     gene            48606..49205
                     /locus_tag="KRH23_000971"
     CDS             48606..49205
                     /locus_tag="KRH23_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224260.1"
                     /translation="MYKKHKFIKNIKKAWYKIKLIDRCLIIVMAILMFQSIYNLFVNE
                     VNSQDTTTIDVVVRTTSAAIFGYFLSANFIKRPLRKYTNTDVSSNLFIDNNLSPKGQE
                     SSQNNIMNVKNTIGFTSEADNYEKKIPINNNEGFEEGETSELQIIIATVICIVALTVL
                     FVVRNFTTTTSASLGTISQMRDFVSGCVGFLLGCPSKPD"
     gene            complement(49392..50264)
                     /locus_tag="KRH23_000972"
     CDS             complement(49392..50264)
                     /locus_tag="KRH23_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HHS5224261.1"
                     /translation="MNINYLYYFQTVCKYKNMTKAAESIHISQPSITLAIKELEKELG
                     FELFYRIGNKIELTPEGKIFLDKSKHFIKQFEDFQCDALDLGKKRKASLKIGIPTVLG
                     TFLLSKILPRFNVIYPDIELKIFEVPTFVGAKMIEESTLDFCIGIIDSDIYDDIDSKT
                     IYKTELYLVTNPKNELAKHPIISNYMLKNVPFVILSEGSYHYKIITKRLEKAKPNIIL
                     HSNQLSTIRYLLENDLASTILYKEIFQNTENLCSIPLERAITANIGVLWRRNQYISHS
                     MKLFIEYMASIHIN"
     gene            50681..52084
                     /locus_tag="KRH23_000973"
     CDS             50681..52084
                     /locus_tag="KRH23_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224262.1"
                     /translation="MKGSDLVKFELMDFLMNPFVLMFAAVITGILFGKIKFGKFNFGV
                     SGALFTGLFIGWLAYSLGNLIIAKGETAAGYKAATVMMGNGIISSDFFDFFLIIFVAA
                     VGLLAAKDMKAVLKKYGARFVILGVLITFIGGSMTYAMTLLSSDKGSSAYEVSGVYTG
                     ALTSSPGLAAALETAGKHAEDVSKEFEKASIKDKKEILKVVDPEGKLDVNTTTSLTQE
                     QIDKYIAYAEAGVGIGHAVAYPFGVLIVILGVNFLPKLFRMDLKEERRKYEKEMKEAR
                     DSVSGKTIPEVPFNIITFFLTCLAGYLVGGIHVFMGPLGYFTLGATGGSLIVSLVLGY
                     IGKIGVVNFRMEEKVLNILKQIGLVFFLAIVGLRYGGKVVDSIMTSGMHLALVAIAVG
                     VTAMMIGFLVGKYVFKLNWILLSGAVCGGMTSTPGLGAAVDALDSDDPAAGYGATYPF
                     ALLTKVILVIVLHKLPM"
     gene            52111..53655
                     /locus_tag="KRH23_000974"
     CDS             52111..53655
                     /locus_tag="KRH23_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA hydrolase/transferase family protein"
                     /protein_id="HHS5224263.1"
                     /translation="MNNEGAFEELNGRLRNKELCDLIMNADEAAKIIEDGMVIGVSGF
                     TPSGYPKAVPLAVSERAKSGEKIKLTVYSGASLGPEVDGAWSEAGIIERRLPYQTNSI
                     LRNNINKGVVDYIDMHLSHSTQFLNYGTIPKVDVAIVEALAITEEGNIIPTSGIGNSP
                     SFIKSADKVIVEINLAKPMEMEGMADIYITENPPNRKPIEINHPKDRIGTTYIPCGLD
                     KISGVVITNMQDKTRPLGVVDEASKKISNNIIAFLREEVKAGRLSKNLLPLQSGVGSV
                     ANAVLYGLCESEFENLTCYTEVVQDSMLDLIRMGKVTMASTTSVSPSPEGLIKFEKDI
                     DFFKDKIILRPQEISNNPEIARRIGVIAMNTAIEVDIYGNVNSTHIMGSKMMNGIGGS
                     GDFARNGAITIFSTESIAKNGDISSIVPMVSHVDHTEHDVMVIVTEQGYADLRGLAPR
                     ERAIKIIENCAHPDYKEQLRDYLNRACKSGAKQTPHILDEALSWHSKFMSTGTMKKAE
                     TFKSAL"
     gene            53686..55077
                     /locus_tag="KRH23_000975"
     CDS             53686..55077
                     /locus_tag="KRH23_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase family protein"
                     /protein_id="HHS5224264.1"
                     /translation="MEKAVENFEDLSKEYINGYIERARKAQREFECYTQEQVDKIVKI
                     VGKVVYYNAEYLAKLAVEETGMGVYEDKVAKNKSKAKVIYNNLKDKKSVGIIDIDRET
                     GITKVAKPVGVVAAITPCTNPIVTPMSNAMFALKGRNAIIITPHHKAIGCSTKTVEMI
                     NEELEKIGAPENLIQILDQQSRENTRNLISSADVVIATGGMGMVKAAYSSGKPALGVG
                     AGNVQCIIDRDVDIKEAVPKIIAGRIFDNGIICSGEQSVIVAEEMFDKIMDEFKNNKG
                     FIVRDKVQKEAFRNAMFVNKSMNKDAVGQSVHTIAKIAGVEIPEDTKIIVIEADGPGE
                     EDIIAKEKMCPVISAYKYKSFEEGVAIAKANLNVEGKGHSVSIHSNTVKNIEYAGENI
                     EVSRFVINQCCATSAGGSFFNGLAPTNTLGCGSWGNNSISENLDYKHLINISRIAYYM
                     PENEVPTDEELWG"
     gene            55270..56766
                     /gene="abfD"
                     /locus_tag="KRH23_000976"
     CDS             55270..56766
                     /gene="abfD"
                     /locus_tag="KRH23_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxybutyryl-CoA
                     dehydratase/vinylacetyl-CoA-Delta-isomerase"
                     /protein_id="HHS5224265.1"
                     /translation="MALMTGAQYIESLRKLNTKVYMFGEEVKNWVDHPMIRPSINCVA
                     ATYDLAHDPEYADLMTVTSNITGEKINRFGHLHQSVDDLIKKVKMQRLCGQKTASCFQ
                     RCVGMDAFNAVYSTTFECDKAHGTNYHDNFVKYLTYIQENDLVVDGAMTDPKGDRSLS
                     PSAQPDPDMFLHIVERREDGIIVRGAKAHQTGSINSHEHLIMPTISMTEADKDYAVSF
                     AVPSDAEGVFMIYGRQSCDTRKLEEGADVDLGNKEFGGQEALVVFDNVFVPNDRIFLC
                     GEWDFSGMLVERFAGYHRQSYGGCKVGVGDVIIGAAALAADYNGANKASHIKDKLIEM
                     THLNESLYCCGIACSSEGHKTEAGNYQIDLLLANVCKQNVTRFPYEIVRLAEDIAGGL
                     MVTMPSEKDFKSDLKVGTSGMTIGEVCNKYFKASSVASTEERMRILRFLENICLGSSA
                     VGYRTESMHGAGSPQAQRIMISRQGNINQKKELAKKIAGIKKEEALNL"
     gene            56901..57176
                     /locus_tag="KRH23_000977"
     CDS             56901..57176
                     /locus_tag="KRH23_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224266.1"
                     /translation="MTCGVRFCGGCNPRYERGKALTIIKEHFNGRVDFSIAQENVEYD
                     LLLIIGGCATLCASYQQYKVKNECVKMWDFSHIERVINVIESAICET"
     gene            57200..58507
                     /locus_tag="KRH23_000978"
     CDS             57200..58507
                     /locus_tag="KRH23_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008410 - CoA-transferase activity
                     [Evidence IEA];
                     GO_process: GO:0006637 - acyl-CoA metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA hydrolase/transferase family protein"
                     /protein_id="HHS5224267.1"
                     /translation="MSWQELYQSKLCSATEAVKQIKNGDTVVFAHCVGEPPALVEAMI
                     ENAEQYKDVEIKHMVSLGSGGYTAKGMEAHFRVNPMFVSGNVRKAIENGDGDFTPAFF
                     HEVPKLLREKRLKCDVVLAQVTPPDEHGYCSLGTSVDYTYEAIKTARTVIVQVNDQFP
                     RTYGEVVHVSEFDYIVEKSQPLFELQPAKIGEVEEAIGKNCASLIEDGSTLQLGIGGI
                     PDAVMLFLTDKKDLGIHSEMISDGTLALYEKGVINGKYKNFDKEKMTVTFLMGTKKLY
                     DFANNNPAVEVKPVDYVNHPAIIMKQHKMVSINSAIQVDLMGQVVAEAMGLRQFSGVG
                     GQVDFIRGVSMGEDGKAIIAMPSITTKKDGTVISKIVSIVDEGAPITTSRNDVDYIVT
                     EYGIAELKGKSLRERARNLINIAHPSVRESLAVEFEKRFKEKY"
     gene            58527..59645
                     /locus_tag="KRH23_000979"
     CDS             58527..59645
                     /locus_tag="KRH23_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxybutyrate dehydrogenase"
                     /protein_id="HHS5224268.1"
                     /translation="MEALRVVPKIFYFDTFKEFNEEFKIGKNDLVITNEFIYEPYMKP
                     LGIDTNLIFQEKFGTGEPSDEMIDSMTKEMKKYNFDRIIAFGGGTIVDICKLLALDVP
                     EKSIDLFEGEVSPKKVKELVVVPTTCGTGSEVTNVAIAELKSKHTKKGLAVEETYADY
                     AVLIPETVKGLPYKFFVTSSVDALIHAIESYLSPKASPFTEMYSLQAIKMIMDGYKKI
                     VDKGEEERFNHLRDFVLASNYAGIAFGNAGCAAVHALSYSIGGAFHVAHGEANYQFFT
                     EVFKMYSRKKPNGKIIKCTKILADALECDPNCDVYGELEKFLNKLIAKKALREYGMVE
                     SQIDEFTDSTIANQQRLLANNYVELSREEIREIFANLY"
     gene            59932..60852
                     /locus_tag="KRH23_000980"
     CDS             59932..60852
                     /locus_tag="KRH23_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-bromo-4-chloroindolyl phosphate hydrolysis
                     family protein"
                     /protein_id="HHS5224269.1"
                     /translation="MYKSENFSKKSVLINSFLSKFLKIIGWGLVSLFTLSALVLSTIS
                     IIIGWAVILPIQVCAVFLLIGGVCIFKGKRLGDQISRYKKYCTIINNRNIIPVELIAE
                     NTSKSLNFIIKDVQKMIDKNYFINTYIDKRNNQIVLTNEDFIPPRYEDVAYEVKEEEK
                     TDESNEVDTIINKGMNYLTQIKEANKNIKSESMGNKIVQVEDVTSKIFDVVKHDPSKL
                     TQIQKFMDYYLPTTLKLLNSYHTLEEQGIDRENITTTMESIENTMNTIVVAFENQLDY
                     LFEDEAIDISTDITVLENMLVQEGLTSGKF"
     gene            60967..62124
                     /locus_tag="KRH23_000981"
     CDS             60967..62124
                     /locus_tag="KRH23_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HHS5224270.1"
                     /translation="MNNLDDIPVMPTLTLDPFGEESNTNDIDNSDLLMKKDEKDPEEE
                     KLSESERKMVKEFAEKIDITNTNMILQYGAGAQKKVASFSETALKSVKTRDLGEVGDM
                     LTNLVTDLKAFSADEKEQSGFLGIFKKANNKISNLKTKYDSAEVNVDKVSKELQKHQV
                     KILKDIAMLDKMYELNLAYSKELTMYIIAGKQKLKDMKEYEMPKLREKARLSGSTEDA
                     QSVNDMVSLCDRFEKKIHDLELTRMVSLQMAPQIRLVQNSNNLMAEKIQSTIVNTIPL
                     WKNQIVLALGISHLNQAMKAQREVSNMTNELLLKNAETLKMGTIETAKESERGIVDID
                     TIKKTNQSLISTIDEVVKIQHDGRIKRQEAEVELSKIENELKSKLLEFTVK"
     gene            complement(62209..63708)
                     /locus_tag="KRH23_000982"
     CDS             complement(62209..63708)
                     /locus_tag="KRH23_000982"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003938 - IMP dehydrogenase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HHS5224271.1"
                     /translation="MAFYFDTPSHTFSEYLLVPGFSSTDCIPANVSLKTPVTKFKKGE
                     EADIYMNIPLTSAIMQSVSDDKMAIALAKEGGISFIYGSQTIENEAAMVARVKSHKAG
                     FVVSDSNIKPDNTLKDILDLKEKTGHSTVAVTEDGTSTGKLLGIVASRDYRISRMDLD
                     TKVSEFMTPMSSIVYANKDVTLKEANNIIWDHKLNSLPVLDDNGNLMYMVFRKDYSSH
                     KENPLELLDSSKRYVVGAGINTRDFAERVPALVEAGADVLCIDSSEGFSEWQKITLDF
                     IREKYGDTVKVGAGNVVDREGFLYLAEAGADFVKVGIGGGSICITREQKGIGRGQATS
                     IIEVAQARDEYFEKTGIYIPICSDGGIVYDHHITLALAMGADFIMLGRYFSRFDESPT
                     NKVNINGSYMKEYWGEGSARARNWQRYDLGGDKKLSFEEGVDSYVPYAGSLKDNVTLS
                     LSKVRSTMCNCGALSIPELQKNAKLTLVSSTSIVEGGAHDVMLKDNRNL"
     gene            64304..65728
                     /locus_tag="KRH23_000983"
     CDS             64304..65728
                     /locus_tag="KRH23_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICB"
                     /protein_id="HHS5224272.1"
                     /translation="MSSSNQSTIKTSIQRIGKFLSGMVMPNIGAFIAWGLITALFIPT
                     GWMPNEKLSTIGDPMIKYLLPLLIAYTGGKAIAGQRGGVIGAAAAMGVIVGADIPMFI
                     GAMIMGPFAGWVIKKFDKFVDGKIPTGFEMLVNNFSIGIIGMLLAILGFYAIGPAIVA
                     GTALIESGVQFIVSKSLLPLVSVFIEPGKVLFLNNAINHGILGPIGIAEAKEAGKSIM
                     FLLESNPGPGLGVLLAYWMFSRGSVKQSAPGAVIIHFFGGIHEIYFPYILMNPVLILA
                     TMAGGAAGILTFSILGAGLVAAPSPGSIFALMALAPKGGLLPVLAGVAVATVVSFLVA
                     APFVKRASANQSEEDSTSLEEAKAKMSDMKSASKNSEKNIEEKQLEVNEIKKIVFACD
                     AGMGSSAMGASRFKNRIKNLDLNIEITNSSVDNLPDDTQIVVTHNTLVERVAKNNSSV
                     EIVSINNFLNDPNLDTLFKRLESK"
     gene            65754..67892
                     /locus_tag="KRH23_000984"
     CDS             65754..67892
                     /locus_tag="KRH23_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HHS5224273.1"
                     /translation="MDNLKKKKITSRQKKIILMIVENSKKNIPITISEIAGTLELSSR
                     TVLRDMSGIEKWFDENDFNFVKKPGVGLILEENIENQNFIIELLEEEKIEKEYSKEER
                     NLIILSKLLVSNEPVKSYYFAKILKVSEGVLNNDFALASKWLERFDIELVRKPGLGVY
                     LKGQEKNFREAYVNLIYDSFNEKEILDMVRNISENIQTDKAIEILSENRLLNLMDRCI
                     IRKVEATLTKKLSDLDVNLADSAYIGLVVHISLALQRIKNGENITMDKEFLKELSITE
                     EFKLAKEIVKGMETDFNMDIPVDEVGYITMHIRGAKQRSSSNHKALNLDDIEIMEITN
                     KMIDLAEDEFKISLKNDERLFKDLANHLGPSINRLNMGLEIRNPLLDEIKSKYSYAYD
                     GVEKISRIIKDKLNINSIPESEIGYIAMHFASAIEKNLMMNTNINIVVACPTGIGTSR
                     FLSTKIENKFPNLNILETISAINIDEEYLKEKDVDLIVSTVELNTSLNYICVGPFMSL
                     DDEQIIKEKIKSIAQNKLINLNAKNDTKSKNRVYEQITESMNIGKDILQFLEEIRFEK
                     FESKNLSELIEDSSRIFAKSSEDIISIKESLKERLKISIPYIEESKILLLHCMSERID
                     IMKLSIIKLENRIVLDSNEEIDNVVFMLLPKNSPSYQRQIMSEISGSLIDNIIFTNKI
                     NKFSIEEMALEVKDIVFNFYTNRLKAFIDK"
     gene            67922..68344
                     /locus_tag="KRH23_000985"
     CDS             67922..68344
                     /locus_tag="KRH23_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HHS5224274.1"
                     /translation="MSKVLNENNIFLGLDSVSKEEAITLAGRKLVENGYVKEEYIPAM
                     LEREKVMTTYMGMGVAIPHGVNEAKKEILSSGIVILQFPNGIDFDGEKAYLLIGIAGV
                     GDEHLEILSNIAVVLDDDLTERLKNSNDKQAFMEAFAN"
     gene            68363..69514
                     /locus_tag="KRH23_000986"
     CDS             68363..69514
                     /locus_tag="KRH23_000986"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008926 - mannitol-1-phosphate
                     5-dehydrogenase activity [Evidence IEA];
                     GO_process: GO:0019594 - mannitol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HHS5224275.1"
                     /translation="MKKAIQFGAGNIGRGFIGGLLVKSGYYVVFADVNEDILNSINKD
                     KKYTIHIRDVECIDEVIDNISAVSSIKEEIIDEIVQAEIITTAVGPLVLTKIASTIAK
                     GIKARKEKGLTSNLNIIACENAIYASSSLKEEVLKYLNKEEVEYLEMYVGFPNCSVDR
                     IVPPGKNENPLDVTVENFYEWNVEKQGFKGEIPTIVGMNLADNLMAYIERKLFTLNTG
                     HAITAYIGYLKGYKTIEESIKDKFICDIVKSAMVESGEGLIKKYNFDSEVHYKYIDKI
                     LNRFKNPYLNDDVLRVGREPLRKLSDKDRLIKPLMTAKSYGLSVDNLILGIGAALHYN
                     NSEDTQSVELQELIKSIGVKKAVAKIANISNDEELLNNIEKSYIFMKNL"
     regulatory      69620..69721
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            69904..70476
                     /locus_tag="KRH23_000987"
     CDS             69904..70476
                     /locus_tag="KRH23_000987"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016763 - pentosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0043101 - purine-containing compound
                     salvage [Evidence IEA];
                     GO_process: GO:0046110 - xanthine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HHS5224276.1"
                     /translation="MKALQEKILREGSVSGNDILKVDSFLNHQIDVAFLNEIGREFKE
                     RFKGEKVDKIFTIEASGIAIASIVSQYFDNAPVVFAKKSESKNLDKDVYETNVYSFTK
                     AREYSVKVSKKYINKGENILIVDDFLANGRAALGLKDLIEQAEANLVGVGIVIEKGFQ
                     AGGALLKANDVRLESLAVVESIDNGTVKFR"
     gene            70540..71190
                     /gene="fsa"
                     /locus_tag="KRH23_000988"
     CDS             70540..71190
                     /gene="fsa"
                     /locus_tag="KRH23_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HHS5224277.1"
                     /translation="MRFFIDTANIEEIKEANDLGVICGVTTNPSLIAKEGRDFIEVVK
                     EISEIVDGPISAEVISLEHKGMIEEAEKLSKIHKNIVIKIPMTAEGLKAVKVLSSKGI
                     KTNVTLIFSAGQALLAARAGATYVSPFVGRLDDISQNGLDLIEEIVDIFSVNSIEAQI
                     IVASVRNPIHVLQAARMGADIATVPLKVINQMIKHPLTDKGIDSFMKDWEGASLKL"
     gene            71342..74266
                     /locus_tag="KRH23_000989"
     CDS             71342..74266
                     /locus_tag="KRH23_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HHS5224278.1"
                     /translation="MDKILREIQREDKKNPYTDQELAEMLNVARSEVISVRKKNNILD
                     SRERRKKILIKDISKIVSENPQMSERKITEILIENGYNISRSAVSKLLKEENLNQSKI
                     GIKDKDPASSGKYVKVSKVVEEDGFEELIGIKGSLKEKVNLAKSAIMYPPNGLHTIIY
                     GETGVGKSELATCMYKYAIKNNIKEENSPFIVFNCADYAENPNLLIAQLFGVVKGAYT
                     GADANREGLVEQANNGILFLDEIHRLPAAGQEILFSLIDRGEFRRLGESSSNRKANVL
                     IISATTENPDSNLLQTFRRRIPMVINLPNMSERPKSERYEIIIKFFEREAKRVNKNFI
                     ITKEVMCALMNYKCTGNIGQLKSDIQVTCARAFSKSIFSSDKVIIDLDSLRDYIKSGY
                     YDCNCKNEKYSEFSVEDIYIDISELVSGKNRILSDNEISEIYNYAEKELKVLESKCFS
                     EEELKNAFIEKLDKKFNAIKNNKNLSDRRSRIDWGGQLKESTLEIMDKVIVFIKEQFK
                     HVNQGLYLALAIHIEHAIGRIKDGKTIINPSLDKIKASMPMEYELSRYIMGIVEDLTQ
                     VTFPEDELGYLAYYINKFCYNEESIKDKVKVVIVTHGKVGIEMSKVVNHILGIECTLG
                     IEIALTDSPSEGIEHVLEELQKIEARKGILVLIDMGSLVILGDEVEKRLGIRCKTVNR
                     VDTLLAMEAGKLATIEGKSLDGIIADLKKNKNYAMINTNKFSYRKNEYGKKNVIITLC
                     LSGVGTALNLKEHIEKQIKEYDTLIEVKPVAFLNNNLEEELNDIESEYNIIAICGTID
                     IDYKNVPFISYNEVLGKNGINKVLEHLNSKQPALNIENQLNNLIHEDLILYNFEGISK
                     EYIIDTLVSKLEEGGYVDSKYILSVYKREAMGSVVMASKVAVPHGLPENVIKPAIAIA
                     RLNKPIVWDNKFMVDLVVLLALKENNKKEIRSLFSKINDQHTLEVLLNTEDKNEIKEL
                     LS"
     gene            74855..75313
                     /locus_tag="KRH23_000990"
     CDS             74855..75313
                     /locus_tag="KRH23_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HHS5224279.1"
                     /translation="MEFINFVSDKVIDLKMDCKTKEDFFKEIHNKVFDLGFVKEEFGE
                     KILARENVFPTGLNLGDYGVAIPHTDAEYIKEQFISVCTFNEPVVFSSMEDQEEKVPV
                     NLAFVLGLNQPHSQLSVLTELMGIMQNKELVDKLMSSTDKEEVLKTLKSL"
     gene            75374..75649
                     /locus_tag="KRH23_000991"
     CDS             75374..75649
                     /locus_tag="KRH23_000991"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HHS5224280.1"
                     /translation="MKKILVACGAGIATSTVVCDKVERLVKENNIQAEVIQCKIAECA
                     TKQEGADLIVSTTILPTTYNIPAIKATAYITGVNTVALDKKILDALK"
     gene            75708..76982
                     /locus_tag="KRH23_000992"
     CDS             75708..76982
                     /locus_tag="KRH23_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002843259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HHS5224281.1"
                     /translation="MDKLLAVVQYILNMGPTVILPITIVVLGMIFRIKFTKALKSGLT
                     IGIGFVGINLVVNLLTSTLGPAAQGMVERFGLNLTVIDVGWPTTASATWASPVAPILI
                     PVCLLVNLLLLYFNKTKILNVDIWNYWHFIVAGAVGYIVTGSYVWAIFCAILMELLVL
                     FIAEKTAKNVQEFYDLEGIALPTGSTASFAPLGYLVGKFVEKIPGINKIQADPDSIQK
                     RFGIFGEPMMMGIILGIILGALAGYDVAGIFNVGISMGAVMLLMPRMVRILMEGLIPI
                     SESIRDFLQAKYGDRELYIGLDAAVATGHPAVISTALILVPITLFLAVILPGNKVLPF
                     GDLATIPFYMAFIVCFRKGNIVQSVITGTIVIAISLYMATNFADVHTQLLQQANMMPE
                     GTTMVTSIDTGGNLLKWGILKLSQLVSSFGIF"
     gene            77112..78164
                     /locus_tag="KRH23_000993"
     CDS             77112..78164
                     /locus_tag="KRH23_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HHS5224282.1"
                     /translation="MKAAVLHGTNDMRFEDIEIKPCESDEVKIKVMAAGICGSDPPRV
                     LKHWKYPVPAIPGHEFSGVIAEVGKDVKNVKVGDRVVAIPFIPCNECEYCKRGLFSLC
                     DDHGMLGAKSFGAFAEYVNIKATNVLLIGDMDFEDAAMIEPLAVAMHGVLNIGVQVGD
                     TVAVMGSGTMGQLVIQGLKIAGAGTIIAVDISDNKLRESKELGADIIINAKDINPVEK
                     IKELTGGKGVDIALECAGSKITQEQCLLITKKKSKIGFLGIAYSDITLSEEAFENIFR
                     KELELKGFWNSYSAPFPGQEWTKGINLVNEGKIKLKEMVSHRFSLEDTYKAFEMIRDR
                     KEEFNKILILPQGVEK"
     gene            78164..79195
                     /locus_tag="KRH23_000994"
     CDS             78164..79195
                     /locus_tag="KRH23_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding dehydrogenase"
                     /protein_id="HHS5224283.1"
                     /translation="MKAVVKTKPGYDNVEVLEVEEPKATGDKVKIKVEYSGICGSDIH
                     SFKGEYANIKAPVTLGHEFSGIVVEVGEDVKNIKVGDRVTSETTFATCEKCIYCETKD
                     YNLCPTRKGIGTQVNGSFAEYVLSREESIHVLPENVSLLSAALTEPLACCVHAALEKT
                     TIESSDTVLIIGPGPIGLLLAQVVKSQGATVIMSGVTKDKERLEIAKNLGVDRTVNVM
                     EESLADVVNEMTDGNGVNKGFDCSGFMPAVNEALRLLRKKGTFVQVGIFAKKLNEMDQ
                     EAIIQRELQYIGSRSQKPSSWITALDLMASGKVNTEALVTRTVGLDEFKEGITALMNG
                     EEIKVAVKS"
     gene            79287..80099
                     /locus_tag="KRH23_000995"
     CDS             79287..80099
                     /locus_tag="KRH23_000995"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HHS5224284.1"
                     /translation="MSTLRDHSNNIRKNIIKMVAEAKSGHPGGSLSIADMLTVLYFDK
                     MNVCAENPKMADRDRFVLSKGHAAPALYATLAEKGFFPEEELITLRKFGSKLQGHPDM
                     KKVAGIDMSTGSLGQGLSAANGMALAGKLDNKDYTVYTILGDGEIQEGQIWEAAMTAS
                     HYKLDNLIAFVDLNGLQIDGSNEEVMNVNPVDDKFKSFGWNVIVINGHSFEEIGNAVD
                     EAKKVTGKPTVIIAKTVKGKGVSFMENNAAWHGTAPNAEQAEQALKDLEGGL"
     gene            80102..81022
                     /locus_tag="KRH23_000996"
     CDS             80102..81022
                     /locus_tag="KRH23_000996"
                     /EC_number="2.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HHS5224285.1"
                     /translation="MGIATREAYGQVLKELAENKDIVVLDADLGKATKSISFKEVAPD
                     RFFDMGIAEGDMIGTAAGLATCGKIPFASTFAIFAAGRGYEQIRNSVAYPNLNVKIAA
                     THAGVTVGEDGGSHQAIEDISLMRGIPNMVVLNPADALEARQAILASIDYNGPVYIRL
                     GRAATPDVNSENYKFEIGKGTVLREGSDITVIATGIMVAKALEAAEELAKEGINVEVV
                     NISTIKPLDEALIKETAKKTGKVVTAEEHSIIGGLGSAVCEALAETKDVVVRRIGVKD
                     VFGQSGTPADLLKHYGLTTEDIVKNIKELL"
     gene            81197..81643
                     /gene="rpiB"
                     /locus_tag="KRH23_000997"
     CDS             81197..81643
                     /gene="rpiB"
                     /locus_tag="KRH23_000997"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004751 - ribose-5-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0009052 - pentose-phosphate shunt,
                     non-oxidative branch [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose 5-phosphate isomerase B"
                     /protein_id="HHS5224286.1"
                     /translation="MKISIGCDHGGYELKEYIKENLINKGIEVEDVGTNSKESVDFPI
                     YAKKVSQNVQSKKSDLGILCCGTGIGMSIAANKFKGIRAAVVSDCFSAKATREHNNTN
                     VLCLGERVIGKGLAMRIVEEWLNSSYNGERHARRLQMIDDIEKENL"
     gene            81673..82338
                     /locus_tag="KRH23_000998"
     CDS             81673..82338
                     /locus_tag="KRH23_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004750 - D-ribulose-phosphate 3-epimerase
                     activity [Evidence IEA];
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HHS5224287.1"
                     /translation="MSIICASIMCADQMKLKEELEALEEAGVKLLHCDVMDGIFVKNL
                     AMGPELLKSISENTTIPLDIHLATETPDKYIDMMSYIKPKYISFHVESSTNVKADIQK
                     LRNYGIGPVLAISPQTSVDKIEEYISLVEGILVMTVNPGFAGQKFNLSVLDKLDKLTE
                     ILKDYDNPPFIEVDGNINKDTIKLMNGKKVDIYVVGTSALFNDKPPISYKDKIEELKE
                     SIK"
     gene            82448..83950
                     /locus_tag="KRH23_000999"
     CDS             82448..83950
                     /locus_tag="KRH23_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase/phosphoglucomutase"
                     /protein_id="HHS5224288.1"
                     /translation="MGDLYKLQNGTDIRGIAYENDSKEVNLTVEEVKKIAKAFHIWLK
                     EKTKKDKVTVAIGTDSRITGSQFRNTVIETLTNDDCNVIDCEIATTPAMFMTTIMDGY
                     NSDGAIMITASHLPYYYNGLKFFTESGGLEKTDIKEMLDIAVKNDSVDYEEVNKKGEV
                     IVKNLIEDYSNLLIDKIRKGVNSSKNYEKPFSGLKILVDAGNGAGGFFAEKVLHMLGA
                     DTTGSQFLNPDGMFPNHIPNPENKEAMESICKAVLDNKSDLGIIFDTDVDRAAIVGKN
                     GKPINKNALIAVISSIVLEEHPKTAIVTDSITSEGLAKFINELQGRHHRFKRGYKNVI
                     NEAIRLNSEGEECHLAIETSGHAALKENYFLDDGAYLIAKILIKVAKLSLEGKTIEEL
                     IENLEEAQEEKEVRIGINKEDFRPYAEDILKDLDSHVKSIDGWSVAPNNFEGIRVNCD
                     ESNGDGWFLLRISLHEPLLALNIESNKIGGAEQIYSKLKLFLEKYDLKGL"
     gene            complement(84262..85854)
                     /locus_tag="KRH23_001000"
     CDS             complement(84262..85854)
                     /locus_tag="KRH23_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase dimerization/phospho-acceptor
                     domain-containing protein"
                     /protein_id="HHS5224289.1"
                     /translation="MVTKLKNLIINDSKAKFILLLLLFLLVSILFEAVYDLNNNFSYN
                     INCYYKEFALPYFYFFGTPVHLSKAELEFVCIGIILSSFLLTILCFTLYKKNKQTKVK
                     FLENVISLFSKVKIELTLILTLVLLTVRFHAFTSNKMFYNTNLIIYNFIIISIVYIIY
                     ENIKYNNYNLKDMSITYVFFSNLLSMYNKKTINKKLAIVFLISIVVQAIIQYLVLIFF
                     MYIYYADAIAIVILFTLVNTVFHFYIYNFLSVKFNYINNISKNIKNIENGNLKYKLEV
                     IGDDEISTLAKSINNITGGLETAVDANIKNERMKAELITNVSHDLKTPLTSILSYVDM
                     LKNNDFDRETINDYINILDKKSQRLKLLIDDIFEASKLSSGDVEFNITKTDIRELLIQ
                     SIVEFEDKIQNSSLDFIIETPEYAVFTMIDGKKTWRVFENLICNILKYSMPNTRVYID
                     MFIKEENIILTFKNISNDKLNLKPEELIERFRRGDISRKTDGSGLGLSIAQNIIELEN
                     AHMEIIIDADLFKVMLTFRRVN"
     gene            complement(85823..86539)
                     /locus_tag="KRH23_001001"
     CDS             complement(85823..86539)
                     /locus_tag="KRH23_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HHS5224290.1"
                     /translation="MNQNILVVDDDREIVDAIEFYLRPDNFNVLKAYDGLEALDILIE
                     NDIKLIIMDVMMPNLDGLKTTLKIREKKNIPIILLSAKSEDMDKIIGLNMGADDYITK
                     PFNPLELTARVKSQLRRYINLGDFSNTNNSNDTNYILKSGGLELNTDTKIVSLDGEEI
                     KMTPLEYKILTLLMSRKGKIFSSHEIYENVWNEDAYSCERTIAVHIRRIREKIEINPK
                     EPKYLKVVWGIGYKIEKLNY"
     gene            complement(87079..87879)
                     /locus_tag="KRH23_001002"
     CDS             complement(87079..87879)
                     /locus_tag="KRH23_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HHS5224291.1"
                     /translation="MTFKNKKFTINKYKILSIILVLCLILTAFSSYVNYSHKKFKDYV
                     VFYVQHQDDEVLWAGSAIVNAIKERGKNHVFVVLVSTGCGISVFDKYKKYENLTNIQK
                     SEYRNREFLASLNSLGVIRENIILLPETNTNGNTDFNYMEKIALTFEEKFKNVTHIAH
                     TYKLDDHLQHLKNGSVIQNLYNAGKIKDAKYFVKPKFADKITFNNKIVYKAHSTEDYE
                     KVKNACQQYKIVDELEYREGIGYKSDHKSFDKLLNNKDVPAILHTPNL"
     gene            complement(88193..88924)
                     /locus_tag="KRH23_001003"
     CDS             complement(88193..88924)
                     /locus_tag="KRH23_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rossmann-like domain-containing protein"
                     /protein_id="HHS5224292.1"
                     /translation="MNIFDILRDYLLVQVDKYNLNMDMISIVSKSLSSKEAIGNTKRK
                     DFPIIVGKEIMLEADFKGAKGQAFTSTPSTFEGSLKDILSLDLHDNPHDRSLFIASLN
                     AVMKYLGKTDRTIHCKNNEPEVCAKKFPEFIKMEFGNPKVAIIGYQPAIIDNIKDFFE
                     TRVLDLNPEFVDTIQYNVKIEDGIRDYEDVISWADLVICTGSTLCNNSIINFLSLNKP
                     VYYYGTTIAGASNILGLKRLCFCSK"
     gene            complement(88911..89606)
                     /locus_tag="KRH23_001004"
     CDS             complement(88911..89606)
                     /locus_tag="KRH23_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HHS5224293.1"
                     /translation="MLKIKNLSLDLPNFKLQENSLNINNHEYFVLLGASGSGKTLFLE
                     TLAGRYPSAKGNVSYKENLISNLPPENRNIGFVYQNFELFPNMNVEDNIRFPLKLRKI
                     PIDEQILKANHLSKLMQIEDIKNRYPKNLSGGEKQRVAFARALIAEPDILLLDEPMSS
                     LDYITKKHISKILKDVYIKYKPTVIHVTHDISEAMFFAHKIGIMNNGKINHIFDLNEE
                     IKNKGESFFYEYI"
     gene            complement(89608..90399)
                     /locus_tag="KRH23_001005"
     CDS             complement(89608..90399)
                     /locus_tag="KRH23_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHS5224294.1"
                     /translation="MKNKFFTTLLTGFFAIVFLFIVSPLLMLIIKGISYVPICLKSVE
                     VQYAITLSIKTSLISTIVCLLLAIPVAYFLHITKLLFKKLIIQIINLPMSLPHLVSGI
                     ALLLLFGRMGIGDSIYKIFKLDFIFTKQGIVLAQVFVNLPLTIKILHTSLNESNEKMI
                     FVARTLGCNSWEAFRFIILPNLKTGIISATVMTWSRALGEFGAVAMIAGSTRMKTEII
                     PTSIYLNMSTGDIDIAIGIAVILIFISLTCLMLFEIFFNREVDKN"
     gene            complement(90409..91221)
                     /gene="modA"
                     /locus_tag="KRH23_001006"
     CDS             complement(90409..91221)
                     /gene="modA"
                     /locus_tag="KRH23_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030288 - outer membrane-bounded
                     periplasmic space [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015412 - ABC-type molybdate transporter
                     activity [Evidence IEA];
                     GO_function: GO:0030973 - molybdate ion binding [Evidence
                     IEA];
                     GO_process: GO:0015689 - molybdate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter substrate-binding
                     protein"
                     /protein_id="HHS5224295.1"
                     /translation="MFKKLSVLALAMIISLSITACNSKENKANDESNTKVTTADDSKE
                     KETLFVYSGAGLKKPMDEIAKKFEKENNVKVEYSYAGSAQLIAQIETSHKGDVFIVGS
                     EPIYSKAFEKELVGEHKTVAHHTPAIVVPKGNPANIQKLEDLNKDGVKLILGDKESNA
                     IGKTTQKILEKNNLKSINDNVVSTAATVNEMIVQLTSSKADATIATKDSVFGNEDVEV
                     IEIAQDKNIDQLISAGIVNYSDKKDLANKFINYIESDEAKQIFKKYGFEPVK"
     gene            complement(91856..>92038)
                     /locus_tag="KRH23_001007"
     CDS             complement(91856..>92038)
                     /locus_tag="KRH23_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005367105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HHS5224296.1"
                     /translation="KWFNNEKGFGFISMESGDDVFAHFSAIQTSGFKSLEEGQKVSFD
                     IVKGARGPQAENITIL"
BASE COUNT        35974 a        10173 c        16000 g        29891 t
ORIGIN      
        1 ttaaaagcac attttttata aaagtgcttt tttataattt ataaaaggta taattataaa
       61 agtcttattc aataaaattt ataattaatt tagatatatt tgtaaataat cagtataaaa
      121 tagatgtttt aatagcataa agccataatt agaaggttat taaaatttat tagatattac
      181 tctagtttat tttaaaaaaa agtattataa tattccttgt gtgaaaatat aggaattttt
      241 attaaatagt tttaatgtgt aaataacatt ctacactatt ttaattaaat atgtaaaaag
      301 taaaatattt aaatagatat attttaaaat ctaactttta atattgtaaa aaaattagaa
      361 atttaacaaa aagtacaaaa attcacattt ttttcataaa gtgtttgact aaaaaattca
      421 catgttgtag aattaaggta gcaggagttt tgagggaggt gtaaataatg ataagaaaaa
      481 taccacaagc agaactaaaa gtaatgaaat tcatttggaa agtagatgtt acagtgacat
      541 caaaagatgt tattgaagct atggaacaaa aatatggctg gaaacaaacc accacactga
      601 cacttttatc taggctggta aaaagaggat tcttagatgc tcaaaaaata gacagatata
      661 cacattacac aataagagta aaacacaaag attatttaag ttttgagaca aaggatttcc
      721 taagtaatat acatgatgac tctttgagaa gcttaatttc agcattacat gatgatgaaa
      781 atataggtaa agataagcta gattttctag aaagttattt tgataattta aaggatgaat
      841 aattatatgc tatatgtttt tgaaaatctt ataaagacaa ctattgtatg tagtcttggt
      901 atttgtctat tattattttt gaaaagatat ttatttaaga agtttagtaa gagattcaat
      961 tattatattt ggttgataat agtctttaga atgttacttt ttctatttaa ttatacaata
     1021 gtatatgaag taaaagaacc caaagaaaat gcagtaggaa ataatattac acaaattgat
     1081 atttctacag ataataatct tatgctgtat atagcttatt tatggttatt tgtaactata
     1141 gtcattgcag tttatacatt tataaagtat acaagattta aaaatctagt tgttgatgta
     1201 tcttatgata ttgaagataa tgatataaac tgtatctaca aaaacttgtt aaaagaatta
     1261 aatataaaaa agaaaattga attaagaggt tctgatgaat tgataagtcc agcaggcatg
     1321 ggattattta aatcttacat attcttacca gactatcctt atagtaaaga tgaactaact
     1381 tggattttga aacatgaatt aatgcatttt aaaaataaag atattttaat aaagttttta
     1441 gttttgtctg ttagaataat atattggttt aatccacttg tatatgtaat gagcaataaa
     1501 gtaaatctag attgtgaatt atgctgtgat gaaagtgttt tgattgattg ttctttaaag
     1561 aataagaagg agtatgcatt agcacttata aagtcaatta aacttagtaa gaattataat
     1621 agtggtattt taacaacaga gtttaataag acaagtttgg aaaagagact tgacagtatt
     1681 gttaagaaaa aaggtaaaag tggaatattg gtgttattga ttttgattac attattttca
     1741 gttacatatt ttaattttga aagtattagt tttgataatt caaattcttt aaggaatatg
     1801 gggattttac aaaaatcagg agtagatctt aaggaagaag atgatattag catgagagtt
     1861 atagattaat atatgtaatg aaaaggtata ttgtcatatt attaataaat taggaggaat
     1921 tatgaaatga aaaatttaaa aaaaatttta ataattacag gttgtctaac tctgatatct
     1981 actagtttgg tatttgcaaa tactactact gatgtagata catcaaagga tgatgattca
     2041 ataataagtt catgtactat aactggttat gaatttacat atgaaaacgc accacaatct
     2101 gtaaaatttg attatgaaaa aaaatgtgaa gcgctaaata taaaaccatc taaaaatgat
     2161 ataatttttg ttaacaaaga ttctatagat gcaaatgatg tagaaaacta tgttgagcca
     2221 aaagcatata ttattagata taaaaaaggt tatgtttttg aagttactgg acctaagagt
     2281 tatacattaa atgtaagtaa tactgtagtc ggatataatc gtgttgaatc aggtaatcct
     2341 gtgcatttag ttcaactttt atgtagaacc ttagatggtt caagtattga tgatgatagt
     2401 gaatttggac ctgctacata taatgcagtt aagtcacttc aaggaagact tggattaaca
     2461 agagatggaa ttgttggaag aagtacttgg gatgcagctg gaagacgtct ttaaaaagaa
     2521 agctattgca cagataattt taaattgctg aatctgtaaa catttacatg tattctttaa
     2581 acaaaaattt attttttaag tgataattaa atttttacta atagggctat ggctttaaaa
     2641 atcatagcct tattttgata tcttttccat ttttgcaaaa gctattaacc ctttaagaaa
     2701 atttcttgtt tttttgaaaa atttctttct tcaaaataaa tacttaaatg agctaaaatt
     2761 tgagcacaat ttctaatttt ctgagttcat ttttaagaaa tatacatggt tgttaagtat
     2821 agtgatttgt gcaaataatt atctaaagta aaaatagatt tcaatttagt aacttttctt
     2881 aataatctat tctaacttcc cattgaattt gtagtatata ttgatgtatt tatttcttga
     2941 ggatacttaa aatatgttac taattcattc caattgtttc accaacctct taatactatt
     3001 gtatattgat tgtactattt tttctctagt gatagctcac ttaatgctac ctcttctgta
     3061 attgtagcat atctttcttt aaatctttta caaattcttt tctattttta tatgatacat
     3121 aatttaaagt atttttaatt tgatgtacag catatctttg tacttaagta ttgggaaata
     3181 tcgctttaat tgcattagaa aattcaacta gtctatatat agaagctgct attaatacat
     3241 ctttaattcc catgtttcta gcatctataa gcacttttag ccaatacttt gaaatttcat
     3301 tttctccaat ccatattctt aaaccccatt ttatgccttc taagttaata catatagcta
     3361 tatagactgt tttgtttatt attctacctc acttctaact ttataatgta tagcatctat
     3421 aaatacaatt gaataaatta tattaagagg tctattttac gagttatgag ttaaaggaat
     3481 aactttatca gtagttttag ttattattga atgagataat atcaattccg taaatacttt
     3541 taagatgact taatatattt tgagtagaca tgtcttttga gtatattcca atcacttgat
     3601 tttttattcc taatatatca ttttcatagt ttctaattac ctttagttca aaatcttcat
     3661 ttcgctttct tgaaatattt aaagttattt ctccaaaatc tgatttaata tttttatttc
     3721 tatatccatt tctagagttt ttagtatttt tgttcttatt atcattctat cataacctaa
     3781 aagttcataa agctccgatt ctaacattta atggattgta ctttcaaata aatcttttag
     3841 tatatcttga atatctgtaa ttgttttgac atcatattct tcaataagtt ttttttatat
     3901 tttagttttt gttaaacata aaaagtatac atcttccttt gtatagtagt gatattttaa
     3961 ttatcataac tttttagaag aatacacact ttattttaaa gacactgaaa atggtgtttt
     4021 tataccttta ttttctatgt ataattttac ttataacata aacttatata aaacagatat
     4081 tttaataaca caaaggtaca attaggagat tattaaaatt tattagatat tactctagtt
     4141 tattttaaaa aaagtattat aatattcctt gtgtaaaaat atagggcgtt ttgttaaata
     4201 attttaatgc ggaaataaca ttctacacta ttataattaa atatgtaaaa agcaaaatac
     4261 ttgaacaact atatttcaaa atctaacttt taatatttaa aaaaattaga aaattaataa
     4321 aaagtacaaa aattcacatt ttttcataaa gcgtttgact aaaaaattca catattgtag
     4381 acttaaagta gcaagagttt tgagggaggt gtaaatgatg ataagaaaaa taccacaagc
     4441 agaactaaaa gtaatgaaat ttatttggaa agtagatgct acagtgacat caaaagatgt
     4501 tattgaagtt atggaacaaa aatatggttg gaaacaaacc actacactaa cacttttatc
     4561 gaggttagta aaaagaggat tcttagatgc tcaaaaaata gacagatata cacattacac
     4621 agtaatagta aaacacaaag attatttaag ttttgagaca aaggatttcc taagtaatat
     4681 acatgatgat tctttgaaaa gcttaatttc agcattacat gatgatgaaa atataggtaa
     4741 agacacgcta gattttttag aaagttattt tgataattta aagaatgaat aattatatgc
     4801 tatatgtttt tgacaatctt ataaagacaa ctattgtatg tagttttggt atttgtctat
     4861 tattattttt gaaaagatat ttttttaaga ggtttagtaa gagatttaat tattatattt
     4921 ggttggtaat agtctttaga atgttacttt ttctatttaa ttatacagta atgtatgaag
     4981 taaaagagcc caaagaaaat acagtaggaa ataatattac acaaattgat gtttctatag
     5041 ataatgattt tatgctgtat ttagtttatt tatggttatt tgtaactata gccattgcag
     5101 tttatacgtt tatagaatac acaaaattta aaaatctcgt tgttgatgta tcttatgata
     5161 ttgaagataa tgatgtaaat tgtatctata aaaatttgtt aaaagaatta gacataaaaa
     5221 agaaaattga gttaaggggt tctgatgaat tgataagtcc agcaggtatg ggattattta
     5281 aatcgtacat attcttacca gactatactt atagtaaaga tgagttaact tggattttga
     5341 aacatgaatt aatgcatttt aaaaacaaag atattttaat aaagttttta gttttgtctg
     5401 ttaaaataat gtattggttt aatccacttg tttatataat gagcaataaa gtaaatctag
     5461 attgtgaatt atgttgtgat gaaagtgttt tgactgattg ctctttaaaa gataagaaag
     5521 aatatgcgtt agcacttata aagtcaatta aacttagtaa gaattataat agtggtattt
     5581 taacaactga atttaataag acaaatttgg aaaagagact tgatagtatt attaagaaaa
     5641 aagggaaaag tggaatattg atgttattga ttttgtttac attattttca gttacatatt
     5701 ttaattttga aagtattagt tttgataatt caaattcttt aaggaatata ggtattttag
     5761 aaaaaacagg tgtagatctt aaagaagaag atgatattag catgagagtt gtaaattaat
     5821 agatttttat agtattataa tttattaaca aattaggagg aattttgaaa tgaaaagtct
     5881 aaagaaaatt ttaatagtca cagggtgttt gactctaata tctactagtt tagtatttgc
     5941 aaatactaat aatgatgtaa atgtatcaaa aagtaatgaa gagcaaacaa caaattcatt
     6001 tacaataact ggttatgaat ttacttatga gaatgcacca caacctataa aatctgatta
     6061 tgaaaaaaaa tgtaaagaat taaatataaa tccatctaaa gatgatacaa tctttattaa
     6121 tgaaaaattt atagattcat ataatattaa tatagatgat tataatattg aaccaaaagc
     6181 atttattatt agatacaaaa aagatttaaa tcgttttgat gttactggtc ctataagtta
     6241 tagcgtaaat ataaatacca ctgtagtagg atatggacat gtagaaaaag ggaatcctgt
     6301 acatttagta caacttttat gtcaacaaat aaatggttct gatattgatc cagatagtaa
     6361 atttggacct gctacatata atcaagtaaa aatacttcaa ggaagacttg gtgtaacaaa
     6421 agatggtgtt gttggaaaag ccacttggca agctgccgga gagcgttatt agaaaagagg
     6481 ttgtcgcact aagaaatagg gcgacaacct ttttatatag aatatattaa tcagtatctt
     6541 agagtctaga aatattttac aataaattcc atataactct accatctata tccttaacat
     6601 tttgacaacc agtcaaaatc atagtctcac ataactcatt cctaaccttc tctataaaaa
     6661 actccacacc atcaagacca ccgccaaaag aagcagtaac aaaaggtctt cccatcaaaa
     6721 cagcatcagc acccaatcca agcatcttaa ctacatcaac accagtccta actccaccat
     6781 caacaagtat tgttatcttt ccctttacag acttagctat atctggaagt acctcacaag
     6841 taccaggagt ataatcaagt actcttccac catgatttga aacaataatg gcactagcac
     6901 caaactctac agccatcaaa gcatcatcta cagtcataat tccttttata ataaaaggta
     6961 atctagtgga ttcaaccaat tctctaatct catcaattgt tttaggagaa aaaggatttt
     7021 cttgaaattg attattaata agtccacaag catcaaggtc tacaccaact gcaaaagcac
     7081 ctgcttcttc agacaatcta attttatcta ttatctttga attattccaa ggctttataa
     7141 atacaattcc atttcctcta ttatctttca acacatctaa attatccagt aaaaaagtat
     7201 ctacattagt atcgccaacc atagcataaa ttccagaatt agaacaacct ctaacaacag
     7261 gctctatgta ttctttttcg gaaactttac cacccatgtt caatatagta cctgatacag
     7321 gtgcagcgaa tataggagaa ctcatttttc taccaaataa ttctatggat gtatctggct
     7381 ttgaaacatt atgtatgact ctcatattta tctttatttt ttctagactt tttctatttt
     7441 caatgaaaga cgaaccactc cctttaccac ccataccagg aacatctcca gcacaagcta
     7501 atccattaca aattttacat actttacatg ttccattaaa gttctctcta gctgatttta
     7561 gtaagtcatt gtaattcata caaaatctct cctttttata atattaaaat tgagtattac
     7621 tatattgaaa atatcttaat tgtaaatata gggatgttat tatgatgagc taaactagat
     7681 aatacatatt agatattttt tattgttgta gatagttaaa ttatatcata ttagatagtc
     7741 aaattttgaa aaaaactaac ttatttaagt atacattttg aaaaaattaa aaaagctata
     7801 tatagatttt taaagaaatc tatatatagc ttttaagttt atgtcaatct tttttattaa
     7861 tgaataaata atatagaata caatatacaa aaaagtttct tgaaatgcta agataatccc
     7921 catttacaaa gcaacatcat tatactgtgt aaatttgaat caacaatgtt ttcaccatat
     7981 tttataataa aatcctctaa ttgtgtgtca ataaatgaat aatatccact tatactatcg
     8041 atgtatgcag tcattaagtg tatacattca tcacttttat ctttatacat atatatctcc
     8101 ccctatatac aatatataaa tttagatacc aaattgtatc atattaaata gttaagtgtg
     8161 taacatctat gcagttatat atttatatca ttatattaat aactaaagtg agttttgaca
     8221 atagattttg ggaaactgga tgttcaaagt gcaaacttgg attttaaaat cattaattaa
     8281 aatagtgtat atgaatatat gtatacataa cttaattata aagattataa acaattactt
     8341 ttattaactt tatttaaatg gtagaataac ttggagatta ataattataa ggaggatata
     8401 atatgagttt atataagttt atatatgatg ataaggaata tttattaaaa gaggagaact
     8461 gtagtgcttt aataaatgat gaagaaaatc cagttcaagg agtaagtatt tcaaaaataa
     8521 ttgatatact taatgaagca gaagaagttg attttgatgt agaatattat caagaagcat
     8581 gtccattatg tttagaagga gtaaaagaaa agaaaaaatt ctttcctttt ttagaatatc
     8641 acttttatat tttcagtaaa gatggagaat atgtaataag taatatatct gttaattata
     8701 aaggactatc ttttaataag ctatcaagag caaataaagt tgataatagt tatattgtaa
     8761 gtgtgataat ttgcgaaaat tgtcaggatt atataattca aatagaaaat tgtatagttt
     8821 agtgtaaagc atgtcttaat ttaagggaaa tttctaaatt gagacagcaa cttttttcaa
     8881 aaatagtatg gaaaattact aaatttatga gataatgtaa gtcggaggtg agttacaata
     8941 tatagtaaat atttggaaga tatagatgat acaattttag attcaatgtt taagctaacc
     9001 ttgaatgaaa gactattgac taataacgat tttattgaaa ataaaattga tgtagtaaag
     9061 aatttaatcg attgctataa aactgaacaa aatagtttga tgttattaaa atcaaatttt
     9121 ttgctagctt tattatatgg tattcaaggg tttagtgaaa aaatgaaaga gtatattttg
     9181 atttcctgta aatatattga taaatgctta cccaaagatt ataaattttt agcacgattt
     9241 tattcacaaa tggctatttt aagtttaaaa aatgaagatg taaataaggc aaatttatat
     9301 atggataaat ttaatcttat ttgtgatgaa aataattttc taattgaaga aattattttt
     9361 aaatcacaac ttatttacat taaggcaagt aagtgtatag aatcttctgt aataattaaa
     9421 gaaatagaaa cgttgtatat aaaaataaaa gaaatcaacg attttaactg taaaaaaata
     9481 tattttttta ttattggtaa aatatatttt ttgtttttgg atgatgctct aattgctaag
     9541 gtaaattttt taaaagcaag aaaatatgca gatttactaa aagatataca agtatcttca
     9601 ttatgtaata taaagatagg tgagtgtgaa tgttcgtttg aaaattatga atgttcaatg
     9661 gaatatttca atgaagtaat aagcaataaa aagtatagaa atgtaaatat aattcaaaaa
     9721 tatagagcat caaacaacat aactaaaata ttaataaaga ctagaaatta tcctgtcgca
     9781 ataaataatt tagcaaaatc tgaagtatat ctagaaaaaa taaaaaatca taacttaaaa
     9841 gaagcagaga agtttgattt atttataagt ttagccatgt attatgcaaa aagtaatgaa
     9901 aaatcttttg aacaatcaat atgctattta gatagagcta aaaacatatt aaatatgata
     9961 aaaaatatag aagaatatac aatatatgat ttagaaataa tttatcacca ggcaaagata
    10021 tattatatct ttggatatta tgacaatgcc ttaaacacaa ataaaaaact ccttgaaaaa
    10081 tctaaaaatg ctaaaaatta taattatgtg aagttagcat acaagagtat atatttgtgt
    10141 tttgaaaaga ttcaaaatta tgaaatgagt atgaaatact ttaaaatgta ttatgagtta
    10201 aaaatgatgt atataaaagc tcgaaataga aattatatag attccttaaa ttatagacat
    10261 gagtatatag aaaaagaaat aaataacatg agaaaagtaa aacttgattt agataaaaaa
    10321 aagtatgttg atcatttgac aagtgcatat aatagaactt ttttgaacga ttttttagaa
    10381 aaacaagaag ttagtgaata ttgcacagca tttatgatag atgtagatta ctttaaagaa
    10441 tacaatgata cttatgggca ctacaatgga gatattgctc ttaaaaatat aactataata
    10501 ataaaaaaat atctaaaaaa agacatgctt atgataaggt atggtggaga agaatttctg
    10561 atattatctg tatgtaaaga ttataaaaaa agtaaaatat ttggaagaaa attatgtagg
    10621 attgtaaaga aatttttaaa caataatttg acagttagta ttggcattga tacatgtaaa
    10681 aatagtagta tagatataag agaaataatt gaaaatgctg ataaagcttt atataaagca
    10741 aaggaaagtg gtagaaatag atgtttgcat tatcatgatt ttaagaattt ttaactgttg
    10801 aaataggatt ggtgatttac ttgaaaagga gtttaataga agatttaaag agaaatataa
    10861 acaagataga atacgatatg ttgactaaat tctatctaaa tttgacagat ttaaactaca
    10921 tcttggatta tcacaaagac cttttaaata caaaattaga agataatagt agagtctata
    10981 ctttatattt aattagtctt ataaactata taaaaaaaga tagagaagca tcatacaact
    11041 atttgataga gtcattaaag tatattaaaa aattgtcatt aaaagataat gcagatataa
    11101 tatctaaaat ttatatttat cttactttat cagctatttc tataagaaaa tatgataagg
    11161 caaataattt ttatttctca gcaaaaaaaa ttataagaca aaatcattta aatgagttgt
    11221 tggtattgtt aaatatgagt ttatgtgtag aaataagtgc tttatatcag accaaaacgg
    11281 atgtaatagc tttagtagaa gaagtgtctt tttttaaaac tttaaaaaat aaagctcttg
    11341 taagtagggc aaattatata tttgggagag tttatttata tttatttaat aactttataa
    11401 aaagtatgga atacttaatt gaatgtctaa gactggctca agaaaataac ttatactcta
    11461 tagaggcttt ctgtaaatgt ataataagtt tgtgttattt agagagtgga aataatgtag
    11521 aagctataaa atacataaat aatgtattag atgttgcaca cagtaataac tcaatatcag
    11581 taactgaaag agtgtctata aagatagacc ttatatgggc atatttaaaa gaagatatga
    11641 ataaagaagc ggaagttatt ctattaaaga ctataaaatt aatgaaagtt gttgaaggtg
    11701 tatataagga ttatttatat tcatttatat ttttatattc agctgaaatt gagttaaaga
    11761 aagataattg tagttttgaa aaggtaaaca cctatttaat tttatcaaaa aatatatata
    11821 aaagttttgg agatgttttt atatataatt ctaaactaga ttacatatat aagttgtatg
    11881 gagatttata tataaaattt ggtaatatag atgaaggtat aagttgttat ataaaaggtt
    11941 taaatttagt taaaaagagt tcattgaatc ttagaaaaat atctatattt tatgggctaa
    12001 tagcaaatgg atatgagcta aaaaaagatt ttaaactggc aatagaatat tataaaagta
    12061 tggattggta ttctgatagg tgggaaaaaa ataattccta taaaacatct caagcaattc
    12121 acaaacaata tgaactcaga caaaaacaag agagtttaag attactagtg gatgataata
    12181 agaaattaga aaatgatatt ttaaaagatg gacttactaa actatataat agaagatatc
    12241 tggaacagca gttggattta tttaatgaaa ccagagacaa aaatatggtc gcaatactgg
    12301 tcgatataga ttgttttaaa agttataatg ataattatgg tcatctagca ggagataaag
    12361 ttatagttaa ggtaactgat attataagaa gtgtatttat agatattacc gaacacataa
    12421 tcagatatgg gggagaagaa attttaatat tagtagattc tatagaatca atcggtgttg
    12481 aagagattga taatatagaa ttatatatta aaagagtttt caaacttctt gaatttgagg
    12541 gtattgaaca tatatattct aaaataaaaa actatataac tataagtgct ggagtaagta
    12601 taaaaagatg tcgtagtaga aaagatgttg aaatattaat tgaagatgca gataagaacc
    12661 tatataaatc aaaaaaagca ggtagaaatc aatacattat aatttaaaat tgaggtgatt
    12721 ttgttgcgaa aaaaaatagg aattatagcc tctgatattg aattaaaaga aagaatagaa
    12781 gaattatata gagaagatgt agaaaatgga actataataa tcgacatact taacctagac
    12841 ttaatggaaa atcaaggtcg tatacttgtt gaaaaaggtg cccaagctat aattggtaga
    12901 ggtggaggtt atagtttagt aatagataca gtaaatgtac ctgttatacc aatgaatatg
    12961 aagtcaactg accttttaag agcaatagaa atagcaaaga aatattctaa aaaagtagta
    13021 ttgattcttg gagacaatga agtttctttt gactatgttg gctggagaaa tgtcataagt
    13081 actgaaataa ctgaagaatg gtttgaatct aagtatgaga taagaagtaa agttgtaaaa
    13141 tatatagacc aaaaagatga agttgtaatc gtaggaggag gtttggcatg ttcttttgca
    13201 aggcaatatg gaattgatag tgtatttgca actgctagtg atgaatctat aagagaagct
    13261 gtagaatatt gtaaaaaatt attagataca ttaggtgaag aaaagtttaa taatgaagtg
    13321 ttacgaaata tacttgatgg tataaaagat ggagtaattg ctatagatag taatggcagt
    13381 ataattttgt acaatgaaag tgcaaaaaac atgcttaaag tagagagaaa atgtgcactt
    13441 aataaataca tcttagatgt atttcctaaa atggagtgga tgttagattg tttacatgaa
    13501 aaagaggacg tagaagatag aaagataaga aatataaata atctaattgt taatactagg
    13561 acaacattga taaaagttga taatagtact tatggagttt taggaataat acaagatata
    13621 accaagctac aaaacttaga aagaaaaata agatttgact tgaatcaaaa aggtctctat
    13681 gctagatata cttttgatga ttttttattt aaagataaat taactaaaga atttattgaa
    13741 gaagctaaaa aaattggaaa aagtgattat acaactttac tttatggaga aagtgggtct
    13801 ggtaaagaaa ttatagctca tagtatacac aacataagta aaagaaaaga taggcctttt
    13861 gttgctataa attgtgctac tatagcagaa aatttacttg aaagtgaact ttttggctat
    13921 gaagaaggtg catttactgg tgctagaaag ggtggaaaaa gaggactatt tgaacttgct
    13981 catggaggga ctcttttttt agatgaaata aatagtctat cctttaatat tcaaacaaaa
    14041 ctattaagag taatagaaga acgtcaaata atgagaattg gttctgatta tataatacct
    14101 ctggatataa ggattatagc agcaacgaat gaatctttaa ccgaaaaaat agttatgggt
    14161 acatttagag cagacttatt ttatagattg agtagtttag agataaatat acctccttta
    14221 agagacagaa gagaagatat aatacctttg tttaacaatt ttgtaaatga agtattaaag
    14281 gatgatggtc tcaatggaat aaacagtata gatgaaaatt ttgttttgac taaagatgaa
    14341 atggataagc tatataatta tagctggcct ggaaatgtaa gagagttaaa gacaatagct
    14401 caaaaatatg ttgtgacagg taaaattaaa ttgagacaag atagagattt taaaactaaa
    14461 aaattacttc ctaactctga agtagacaaa tttaattctg aaacgacagc aagtgtagaa
    14521 gtccaagatg aatctataaa tataagtaag ataaatgatg gtaagataag tatagatata
    14581 aaagaagtaa ataagtatgt tgaagaaaaa ataataagta tgctttttgc tcagggactt
    14641 tctaaaaatg aagttgcaca agttcttgga ataagcagga catctttatg gaagaaatac
    14701 aataaaaata tttaaatata attacatata aattattttg aagtaatgtt aattttttaa
    14761 aacaagtgtt aagaaaaatt aacattactt ttttgcaaat ttttattttt ttagacaggc
    14821 atatatattt ataagaaaaa tagttaaaac acttaattta ataatgaaaa aaataataat
    14881 tctaaacaaa atcaatttta cataaagtgg gatttattgg catagtaatt gcttaatata
    14941 taatgtaaga gtaaatacaa ttttaggggt gatggtatga gtcaaagtat ggttggtaag
    15001 catgcaatgt ggccaaaaga aaatgatgtt atatttagca tatctggcag agctcaagca
    15061 gcagagaagg cttttggtat ggataatgta ataaatgcaa caataggcgc tctaatggat
    15121 gattcaggaa aattgataac aatgaaaact gtatatgaag aatataaagc attagataac
    15181 tgtgagatag gtgcatatgc agctcttgaa ggtcaaccag attacttaga agcagttaaa
    15241 aaagtatttt tcagagatta cttaccagaa ggacatataa gagtattagc ttcaccagga
    15301 ggaagtggtg caataaaatt agctgtatgg aactatacta atgaaggaga tgaggtatta
    15361 acatctgatt ggttctggag tccatatgta agtatagctg aagaggctaa tagaaaagta
    15421 gttaattacc aactttttga tgaaaataga aggtttaatt ttgagtcgtt taaagaaaaa
    15481 tttgtaaata tagcagaaaa acaaggtaga gtctttacaa ttataaacac accagcgcat
    15541 aatccaactg gatatagtgt tgcagatgat gagtgggata aaatattaga cttatcaaaa
    15601 gaagtcgcaa aagataaaga caaaaagata atatttttcg tagattcagc atatattgac
    15661 tttgcaggtg atgatgatgt atgtagaaag ttttttaaga aattttctaa tttgcctgaa
    15721 aacgttctcg tattggttgg attcagtatg tcaaaaggat ttacagctta tggtatgaga
    15781 atgggggcta taatttgtat atcttcaagt gaagatgtag ctgaagagtt ccattactca
    15841 tgtgttcatt catgtagagc aaattggtca aattgtaata gaagtgctat ggcagtatta
    15901 tctaacattg taaatgaccc taaaaaattc aaagaatatg aggatgaaaa agaaatatac
    15961 aaaaacatgc ttactagaag agcagatgta tttgtaaaag aagctgaaag agtaggatta
    16021 gaaattcttc catatatagc aggtttcttt gtaagtatac catgtgataa tccaaaagaa
    16081 gtatgtgaag aattgactaa acataattta tttgcagttc cattaaaaat gggcttaaga
    16141 tttgcagttt gtgcagtttc tgaagataaa tgtaagaaag caccaagtat tataaaagaa
    16201 gcacttgaaa gtttagaagt aaaaataaat aattaatttc attgaacaaa ttgggtggac
    16261 tatgaattta ataattgtag atggagggaa ttttatatga aacaattgat gacaggtaat
    16321 gaagcaattg cacgtggagc ctatgaggct ggtgttaaat atgcatctgc atatccaggg
    16381 actccaagta cagaaatatt agaaaatata gcaacatata aagatgcaat agttgcagag
    16441 tgggctccaa acgaaaaggt agcacttgag gctgctatag ggggttcaat tgcaggagca
    16501 agaacaatgg cttctatgaa acatgttggt ttgaatgttg cagctgatcc aatatttact
    16561 tatgcatata caggggtaaa tggtggtatg gtacttatta cagcagatga gccgggaatg
    16621 cattcatctc aaaatgagca agacaatagg atgtatgcaa aatttgcaaa gataccttta
    16681 tttgaaccat caactagtca agaagctaaa gatatgataa aagaagcttt tgaagttagt
    16741 gaaaaatacg atacaccagt tttatataga gttacaacaa gactttgtca ttcaaaagga
    16801 ttagtggagt gctatgatag agaagaagtt gaaattaaag agtatgttaa aaatgctaag
    16861 aaaatggtaa ctgttccagc aaatgctcaa ataagaaggg gcgttgttga agaaagaatg
    16921 gaaattctta aaaaattctc aaatgaaact gatttaaact actatgaaat aaatgataca
    16981 aaaataggtg ttatagcatc tggtatgtgt tgtaattttg ccaaagaagt ttttggaaaa
    17041 aatgcatcat atatgaaact aggatttaca aatccattac cttatgaaaa aataaaagaa
    17101 tttgcagaaa aagttgataa aatatatgtt atagaagaaa atgacccatt tatagaagaa
    17161 caaataaaag catatggaat agattgtatt ggaaaagatg taataccacc atatggagaa
    17221 atgacaccag atgttttaag aaaagctata tttggaaaaa caaatgatac tatagaatac
    17281 aaatctgaat tagtaacacc aagaccacca agtttctgtg caggatgtcc acatagagga
    17341 ttcttctatg aacttggaaa gagaaaaaat ttaatagttg gtggagatat aggttgttat
    17401 actcttggat ttgctcctcc atataatgga atagattatg ttgtttgtat gggttctgct
    17461 tttggaactg cacatggagc tcaaaaagtt cttaatatga aggatgataa tgaaaaaaga
    17521 ttggtaggtg tacttggaga ctcaacattc ttccatacag gaataaatgg acttttagat
    17581 gttgtttaca atagaggtaa ttctatttcg gttatattag ataatagaat aactggaatg
    17641 acaggtcacc aagaaaaccc aggttcagga tatactttac aaggtgctaa aactaaagaa
    17701 gttgatatag aaggattagt taaagcttgt ggaatagaac atgtaagagt tataaaccct
    17761 aataatttaa aagaagtaaa tgaagcacta gattgggctt tagctataga agatgaacca
    17821 tcagtaataa taacaagatg gccatgtgta cttaaaaaat tctctaaaga agatatagaa
    17881 gaatttaata atccatttaa gactaagtgt aaagttgacc atgataaatg tataggatgt
    17941 aaattatgtt tgaaaactgg atgtccagct ctatcatttg ataaagagaa taagttatca
    18001 aatatagata gaaatcagtg tgtaggatgt ggagtatgtg cacaagtttg tccaaaacaa
    18061 gcaatagtta aggaggaaaa ataatatgac taagagtata cttttggtag gtgtaggagg
    18121 tcaaggaact atacttgcta gtaaattatt aactatggga ttgatggaag ctggatatga
    18181 tgtaaagatg agtgaaatac atggaatgag tcaaagagga ggttcagttt cctcacaagt
    18241 tagatatgga gattgtgttc attctccagt tatagaaatt ggtggagcag atatattagt
    18301 atcttttgaa aaaatggaag ctttaagatg gttcaattat ttaaaaccag aaggaaaagc
    18361 tttagtgaat aatcatagga tagattctat gactgtttta atcggaggag ctgaatatca
    18421 agaaagtgat atagatgcag agttaagtag attaaatgca aaagttataa atgcagctga
    18481 taaagctgaa gaactaggaa attcaaaaat aatgaatgtt attttattag gatgtctagt
    18541 taaatctatg caattagagt ctattgattg ggaaaaaatt ataagtgaaa atgttaaacc
    18601 aaaatttgtt gaattaaaca taaaagcttt ccatgaaggt atggaaatgg ttagcaaata
    18661 gtttataata gatataaata gactatagaa attaaggtga aaggaagaaa attatgactt
    18721 acagaatatt agccataaat ccaggttcta cttctacaaa aatagcagta tatgatggag
    18781 aagaacaaat tcttgtgaag acgatagacc atccagctga agagattgca aaatataata
    18841 ctatacaaga ccagtttgaa atgcgtaagg aagcagtttt gaatattctt aaagaaaata
    18901 gtatagactt aaaatctctt agtgcaatag taggaagagg tggagtttta ccaccagtaa
    18961 aatcaggagc atatttagta aatgaagaaa tgattgatgt actaagacat agaccagtac
    19021 ttgaacacgc ttccaattta ggtgctgttg tggcacatgc aatatcagaa cctcttggaa
    19081 tcaactcata tatttatgat tctgttgcag tagatgagct tatagatgta gcgagaatat
    19141 ctggactttg tggaatggat agatcaagtg cagggcatgc attaaatact agagcaatgg
    19201 ctttaaaata tgctaaggat aaaggaaaag attataagag cttaaactta atagtagctc
    19261 acattggtgg aggagtaagt atttatcttc atgaaaaagg aagaatggtt gatatgctat
    19321 ctgatgatga aggaccattt tctccagaaa ggtcaggaag agtacctgct acaaaattag
    19381 tggctgcctg ttattcaggt caatattcag aaagagaaat gactaaaaag ataagaggta
    19441 aaggtggtat agtttcatac ctaaatactg tagatgctag agaagttgaa aaaatgatag
    19501 cagaaggaaa tgaagaagca aaaattattt atgaagcaat ggcttatcag ttagcaaaag
    19561 gtattggaga gttagcaact gtagtagatg gaaaggtaga tgctataatt ataacaggtg
    19621 gaattgcata ttctgaaatg tttacttcaa tggttaaaaa gaaagttgag tttatagcac
    19681 cagtagaaat tatggcagga gaaaatgagt tggaatcact tgcttttgga actttaagag
    19741 tactaaatgg agaagaagaa gctagaattt atagtgaaaa ttaataagaa aaactaaaaa
    19801 tgtttatata ctaaaaaagt ggtatatccg ttttttatac acgaaagctt agagtatagg
    19861 tgaaaatgta taaaatttgg attgccactt tttataatta aaattttatc ttaacctaat
    19921 aaataattct gtaaaatttc gtatttatat atatatttta ttggtattta ttgttattat
    19981 tattatgagg agtgattttt gatgggaaaa ataagtttaa aaagtatgat aagattattt
    20041 tcaggttttt ttatatttgc aatttcttct gtgcttatga ttaatgcaca tgtaggtctt
    20101 atgccttggg atgtacttca ccaaggttta tctataaagc taggcataac tataggtcag
    20161 gcttctataa tggtaggagt tgtaattgtt atattggatg cagtttttgg tgaaaatata
    20221 ggatggggta ctttactcaa catgacattt ataggaattt ttattgattt agtaatattt
    20281 tctggagtga tacctcatgc aagcaacact tatataggtg tgtttatggt tgttatagga
    20341 attattttgg cagctatagc aagttttcta tacttaggtg tttgtttagg aagtggaccg
    20401 agagatgggc ttatgattgc tcttcagaaa aaaactaata aatctgtacg tcttgttaga
    20461 acaattcttg aaatactagc attagttgtt ggatggttat taggaggttc tgtaggtatt
    20521 ggtacgcttg taagtgcttt aggtttagga tatgtattac aaatagtgtt tagaatattt
    20581 aaatttgaca caaaattgct gaaacataga tttattatag atgatataag agaatggaag
    20641 gaaaagaaaa gcaatgaaca taaatgtaaa tcaagtattg taataaaaaa tgagcagaat
    20701 taattatgct aaaatatatt tgtagtttat ctaatttata gtaaagtcaa ggagattttg
    20761 aaatggaatt atgggattta tataatgctg atggaattaa aacaggaaat gttataaaaa
    20821 gaggtaattc tattgaagaa ggttattacc atttggcagt tgaagtgtgg attttaaata
    20881 gtaactctca aattttaatt cagaaaaggt ctaaaagtaa aaaaacattg ccaaatatgt
    20941 ggggaatgac aactggatgt attgtttctg gggaagacag tttagaagga gcaattcgcg
    21001 aagcaaagga agaaataggg atagatataa ctaaagatga gatgaaagtt tttagaagta
    21061 tgattcatga agatactctt tgggatgtat acttagttaa aaaagaatat gatatatcca
    21121 aagctatttt acaggaggaa gaagtaagtg atataaagtg ggtaagcaca gatgaaataa
    21181 gacaattact aaaagagggt ttgttttttg aatatccaga gatatacgaa ttgctatatg
    21241 agatagataa taataaatta aatatatgat gtagagcaga tttcagtata agtaagatta
    21301 tttaaaatgt atcttctcta aattttaata ttgttttatg aaaattaata agttattttt
    21361 agtatttttc tacttgtttt ttgagattaa aataaaaagg gcagtcatta taaagtcata
    21421 aaaatttggg gaggatttaa actatggaag ataacaaagg attggcacgt gacagttcaa
    21481 aatataaaat tgtttctata tctgtcgtag taattattct aattacattt tggtatatgt
    21541 taaatatggt gcttttaaca tttattatga cttttatttt ctataacttg cttgtagcca
    21601 caagaaaacg aattaagaag ttttcttctt taaatattcc agattcattg ataattatag
    21661 tgttatatgc actatttgct atattgttag tattgattag ctatgcagtt gtaccaataa
    21721 ttatagttca acttacagag ttgagtaggg tttttagtga ttttgatgta aatcaatttg
    21781 ctcaatcttt aggaccaaaa ttgtatccta ttgtctcaaa gctggatttt aataaatata
    21841 tttcacaagc agggctactt atagcatcaa cagcaacaaa agttggaagt tttggagtaa
    21901 atatattatt ggcattttta ctgagtttac tccttttact tgaaaaaaat gaaattaaaa
    21961 attttggaga taaactttct gatagtaaga tttcttttat ttataattcg cttgtatttt
    22021 ttggaaagag ctttgttaaa aattttggtg aagtaatgaa agtacaagtt atgattgcct
    22081 ttataaattc tgttgtttct atgatttttt taggtttcat gggattccct caaatatggg
    22141 ctttaggatt tatgattttt gtgttgggtc ttattccagt agcaggagtt atagtgtctt
    22201 tgattccatt aactgtaata gcatttaata caggaggaat aacaaaggtt tttggagttt
    22261 tacttatgat ttgtatagtg catgcagtag aaacatacat attaaaccct aagttgatgt
    22321 cgaatagaac taaacttcca gtttgttttg tttttattat tttacttgta ggagagcatt
    22381 atttaggtgt atggggatta ctaattggag ttccaatatt tatgttcctt atggatattc
    22441 tgggtgttaa atttacttct aggtaatata ttaaaataat aatttatttt tatatataaa
    22501 ttatgaattg ttttaaaaaa gaacctataa atagacatca ttaataaaga catctatttg
    22561 ataggttcaa ttttgctttg tataaatact ataaaactaa ataaaaagaa atttatttca
    22621 tttcaaaagt ttcacaactt gcatttcttt catttatatg aactttttca gctttgcaaa
    22681 gttcattttt attgtattta cattttacag cttcacaatg aatgttatct gtatcaactt
    22741 ggttagtttc attagaacga ctagttatac cagatgtata tttgtcttca aaagaagcac
    22801 aataagtatt ttctgtagta gttgcttgca ttccatctac ttttatacta ccagcataac
    22861 aatatccact agtattataa gcacaattag tagcagcaca atttaaatta ttatttttca
    22921 taaataacct cctaagtttt atttaaactt attatgtgaa gttatctaaa ttttatacac
    22981 ttatttacaa ttacatttat cacatttaac aactacatct ttggaagttt cccttcctaa
    23041 atttttatta acatgataca catcaacatt ttcagttgat ccacatatag aacatttaaa
    23101 attgttttct agtagggttc tttctttaaa taacttccaa tacatagaat tgatgtaatc
    23161 attataattt accttgaggc atgtctcaag aaagtttatg tatagattgt ctaaatctcc
    23221 tgtatttaat tctgtatatt ctggttcaaa atattcacaa catcctctaa aatcgggctt
    23281 tgtatctgaa ataacacatc taatatcata tctatagtct aggctaggcc ccttaaatga
    23341 aagatgtgtg caaaaagaac aagatgtttc tggtagattt ttttcaagtt catgtaattt
    23401 attattcata agtattcctc caaaaaattt attttaagta tataaatgaa tagattattt
    23461 taaaactttt atttatttat attagagatt taggataaat attccaataa ggagtaaata
    23521 cttaagtatt tattactgta ttaaataaaa aagaggcaaa tctaacttga gattgcctac
    23581 ttttttatca ttttttaata aaatttattc taagtattat tttatttaga tttagtcagc
    23641 caacttagta tctgctttgc tttttaactt tctaccagag cgtacagtta aaatagcata
    23701 taatacagta aatatggcag ctaaaacata tgatatattt atgtttaagt taaatccaat
    23761 ttgagcatta aatatataac tgaatataac aaaggaataa aacataccag gaattaagct
    23821 tataatataa ttcttttctt ttattataag gtaaactgta atcattgcaa atgcaaatat
    23881 ggcaatagtt tgattactcc aagagaagta tctccacaat atattaaatc cagaagcact
    23941 aagctttgca aatataagga tggctatgac aggaataaat atacagattg acaatataac
    24001 acgatgtttc ttttcctttt ggtcataatg aaagtaatct gcaagcatta atcttaaaga
    24061 tcttaaagct gtatctccag aagttattgg taaaacaatt acacctatta tagctatgat
    24121 accaccaata gaaccaagta aatctcttgc aaccaaacct attacatcag gagaacctac
    24181 taattcttta ggtattcctt tattgtaaat acccatagca gctgcagccc aaatcattgc
    24241 aattaaacct tctaaaatca tcatattata aaaagtagtt tttccttctt tttcatttga
    24301 aactgatctt gctataagag tagcttgagt tgagtggaat ccagaaacaa taccacaagc
    24361 aactgtaaca aagaatgtag gaataagagg aataccatca ggatgaatac ctttccaatt
    24421 tgcaagactt aaattagcta aatcataacc ttgtgtaaag attccaattc caacaccagc
    24481 agcagataaa agtagaatag ctccaaatat tggatatacc tttcctatga ttttatcaat
    24541 tggaaatagt gttgcacaca agtaatatag aaagataagt ccataaacta tccagacaac
    24601 tggattattt atagtcgatt tcatatttaa aatttgagta acaactaaat ccccaggtgt
    24661 ataaataaaa actgcaccaa ctaaaagcat taaaagacaa aggaatatat tatagacttg
    24721 aaatacttta ttacctaaaa atctactgat aagagaaggc atttgtgctc ctttttctct
    24781 tatactaatc attccactca tatagtcatg caaagctcct ccaaatacac agccaatagg
    24841 tattagtatg aatgctattg gaccaaacaa tataccttgg ataggtccta gaattggtcc
    24901 tgtaccagct atattaagca actcaattag actatttttc cattttttca ttgggacata
    24961 gtctactcca tcactttgag caagtgcagg tgtttttcta tcatctgggc caaatacttt
    25021 ttcacaataa gcaccgtata aagcacctcc tattagtaat atagccaagc cgattaagaa
    25081 tgttgtcata atatcacccc atttataaaa ttttttggtc tttgtataca tattatctaa
    25141 atgtgtagat ttatattgaa tttaattctg gacaacctac aaattctata aagtattaca
    25201 actaatataa tttcagaaat aaatacatat acataaccat gtacttagta tacaggtatt
    25261 tggtaatatt ttcaatgtta tagcaataaa gaatataaac aaaattctga taatatttta
    25321 caaaaaaatt aaaaaatata aaaattagtt taaatagatg gagaaaaaag gaaaatcaat
    25381 tgagaatata aatgtctata tcttaacaat attaagaggt ttaaaattct tgaagaaaga
    25441 atagtcaagt gatataatga gtttacaggt gtatatacac tagtacatat agaaagcggt
    25501 gcaattatgg ataaagattt aacatatcaa atcaaagagc taaagaaaga aaaaaatgca
    25561 ataatacttg cccattttta tcaaccacca gaaatacaag aattagcaga tgcagttggt
    25621 gactcatatt atttaagtga gattgctaga gattgtaaag aagaagtggt tgtattttgt
    25681 ggagtaaggt ttatgggaga aagtgctaag atattatcac ctgaaaaaac tgtattgatg
    25741 ccagtaagta acgctgggtg tgctatggca gatatggtag atgaagaagg cgtgataaaa
    25801 ttaaaacaac agtatccaaa tgctttggtt gtatgttata taaactctac agctaaagtt
    25861 aaggcacatt gtgatgtttc tgttacatct tctagtgcaa ttaaaatact agaaaacata
    25921 gataataaag aaattatatt ccttccagat aaaaatttag gaggatatat tgcagaacaa
    25981 tttccagata aaaactttat attttgggac ggatattgta aataccataa caatataaga
    26041 gctgaagaaa taattgagtt aaaagataag tataaaaatg cagaagtatt agtacatcca
    26101 gaatgtaaaa aagaaataag agatttagga gattatgtag gtagtacatc aggaataata
    26161 aaatatgcta ctaatagtaa aaacaaagac tttataatag caactgaaga aggtatatta
    26221 catgaattaa agaaaaataa tcctaataaa aacttttata ttcctggtgg aaaaatacta
    26281 tgtacagata tgaaaaagac aacattagaa aatttatata gtacacttaa aaatatggaa
    26341 aatgaagtta ttgtagaaga tgaaatcatg gaaaaggctt taaattcact gcttaacatg
    26401 cacaaattag cagaaggata gagggataga cttatgaatt tagaacaaga tgttttaata
    26461 gttggaagtg gagtttcagg attatactgt gcattaaatt tagataaaag tttaaatgtg
    26521 ctagtagtat cgaaatcaac aattgaaaac aacaatacat atcttgcaca aggtggaatt
    26581 tcaactgcta gaaatattga tgatatagaa tcctttgtag aagatacaat gaaggctggg
    26641 cagtataaaa atagagttga agcagttcaa gtacttgcag atgaatctat agaaaatgta
    26701 gggcagatag tagaatatgg tatgccttta gacaaagaaa atggagagat agattacaca
    26761 agagaaggag cacatagtgt aaatcgaata gttcatagta aggataatac tggagaagtt
    26821 gtttttaaaa ctttattaaa agaagctaaa actagagaaa atataactct tatagaagat
    26881 gcatatcttt tagatatatt aaaagatggc aataaatgta taggagctag aatttttaaa
    26941 tctaaaaaag agattcatgt tttttcaaaa atagtagttt tagctacagg tggaattggt
    27001 gggcttttta aaaattctac taatcaaaga catcttacag gtgatggaat tgcaatagct
    27061 ttaagaaata atataaaaat agaaaattta gaatatattc aaatacatcc tacagccttt
    27121 tatgaagaaa ataatgaagg taggagaatg cttatatctg aatcattaag aggagaggga
    27181 gctaaacttt taaataaaaa taaagaaagg tttgtggatg aacttcttcc tagagatgta
    27241 gtttcaaaag ctatttttga gcaaatggaa aaagataaat taccttatgt gtatttagat
    27301 gcaacacatt tagatagtga atatttaatt aatagatttt cttttattta taatgaatgt
    27361 ttagctagag gaacagacat aacgaaagaa tgtataaagg tatctcctgc acaacattat
    27421 tttatgggcg ggatacatgt agatttggat tcaaaaacat ctatggaaaa tttatatgca
    27481 gttggtgaaa ttagttgtac aggtgttcat ggagccaata gattggcaag taattcatta
    27541 cttgaagggc ttgtattttc aaaaagagca gctaaaaata taaactcagt tatagataat
    27601 gtaaaagtta agtttataga tgtaccagat atggatatag atatagaaca ggtaaaaaaa
    27661 gaaaataaaa tattagtcat aaaagaaatt gaaagaacaa gtgaggattt tggcgatgaa
    27721 ttatttgatt attgatagaa tgatacagga tgctttgata gaagatgttc caagtgaaga
    27781 tataacaact aattctattg tggatgaaaa ttctaaatct actgtagatt taatttgcaa
    27841 acaagatggt ataatagctg gcttgggtgt atttaagaga gtttttgaga tacttggtga
    27901 tgtagatgta aaattatata aaaatgatgg tgatagagta aagaatcgtg aaaagatagc
    27961 tgtattaaca ggtagtacta gaaacttact tgtaggagag cgtgtagcat tgaattattt
    28021 acagagaatg agtggtatag ctactattac aagtaggtat gttgaaaagc ttgaaggtac
    28081 aaatacaaaa ttattagata gtagaaaaac gatacctaat cttagaatat tagataagta
    28141 ttctgttaaa gtaggtggag gatgcaatca tagatttaat ttatctgatg gaatattgct
    28201 taaagacaac catattgggg ctgctggtag tgttaagaag gcagttgaat tagctagaaa
    28261 aaatacttct tttgttagaa agatagaagt ggaagtggaa actttagaca tggtaaaaga
    28321 agcaatagaa gctaatgcag atataataat gttggataat atgagtttgg aaatggcaaa
    28381 acaagcagta gatattataa atggaagagc cattgtagaa ttttccggaa atgtaaattt
    28441 agatactata gaagatatag gaaaaattgg tgtggatgtt gtttctgtag gagcgcttac
    28501 acattctgtt aaagctctcg atataagtat gaagaatttg agaaatatat aaattttata
    28561 ttgaaataaa cttaattaaa atagactcct taaatttgtt ttataaattt aaggagtcta
    28621 ttttttattc attaaaatta ataaaaatag aaaaaaatca atcaataatt taataaaaat
    28681 agataaatac tatatacact tttaataata tagttaatat ctattttaca gataaataag
    28741 aataaactta taatataatt gtatctgtaa aattttgtaa aatataaaaa gtataggggg
    28801 aataaaaatg aaagtagctt atatttttag tagtactaat acacataaaa ttctagacaa
    28861 aatgataata ccacaacttg aacaaggaac tcatggagta gacgttctag ggatgttttt
    28921 ctttatggat aataccttat ttttatctaa aggtaatcct gtaggcgaga gactaagtaa
    28981 attacatgaa aaaactgata tgataataat ggcttgtgac caatgtgcta tagaaagagg
    29041 tatagagaat aatttggttg atggagctac aattggatgt ttcccaaacc tatatgcttg
    29101 tttaggcagt gcaggtgtgg accaagttat aacgttataa attagtatag gatacaatcc
    29161 atagaaaaat ttattttctg tggattattt taagtaaaag ataaattgtt taaagtaggg
    29221 gattaacaaa tgtctaaaat tttagttgaa tttataaaca cttgaccatc ttgtgatgaa
    29281 catggagtgt ttataaaaaa aatgtcagaa aagtatgctg ataaattgga aataaaatta
    29341 tatcaagcag ggaaagattt ttcgtatata aaaaaatatg ggattataac aaaaggaact
    29401 ttaataataa atcagaaaaa gaaatatgat agattaaata aagatacaat tgaaagggca
    29461 atagtagaag ctataaacaa taattaaaag tttaaaaatt aggagtatca aaaatgaata
    29521 tattagaaat tgttttaaat ggagttaaag atactatagt agcttctata gttacactga
    29581 atggagcatc aggatggctt atgataagtt ttatattggc aggtgtactt cacaatgttt
    29641 taactccaag aaggtttcaa aaacaacttg gaaataagaa attttcttct ttaattaaaa
    29701 gtactatctc aggaatgttt ttaccaatat gtagttgtgg agtaatacca cttggaataa
    29761 gtatgtatta ttcaggagca tatttaggac cagtacttgc ttttatgaca tcaactccaa
    29821 taataaatcc aatagctgta gttctttgtc taggtctttt aggtcctaaa gttacaatca
    29881 tttatctaat agctggtttt ttagtaccat ttttagtagg atttttagga aattgttttg
    29941 gaaaagaaga attatcactt cataatgatt cagaggaaga agtaatagaa ttagaagaag
    30001 aaaaaagaag ttttatggaa aatatgattg atggtcttaa atggtctttt ggtgaattag
    30061 cccttactat tagtaaatat gtagtaatgg gtatggtttt tgcaggattt ataacaacta
    30121 tttttccaaa tagtataatt caaaaatatt taggaaatcc aggtttgcta tctcttggaa
    30181 gtatagcaat acttgcatgt gttatgtatg tatgtgctgt aggacatata ccgtttatag
    30241 cagcccttgt tgcaagtgga gcatctcctg gtatagcgat aacatttcta atagctggag
    30301 cagctacaaa tctaccagaa cttataagta tgtttaaact tattggaaaa agaactgtta
    30361 ttatatattc tgtaactttg acactgtctt caataataat tggatatata acaaatttac
    30421 ttttagtgaa taataactca gtaaatttag atgcaacaaa ttcttcaata cagttggcaa
    30481 ataaactaat gttaaatata cctgatagtt ttgagtatgt atgtactatt ttaattattt
    30541 tatttgcatt taaatcaata ataccaaaga tgaaagaggt cataggaaat catgcttaaa
    30601 aagatagtta taatatcctg tatagtagtt gtgttaatca ttttatcaaa aatagttgat
    30661 gataacatca aagaagatgc ttctattcca aatgtgaata aagaaacatt agaatatttt
    30721 agaaaaaatt ataaagaaga cataataact tgtgctgaag aagacttaaa taatgatggg
    30781 aaaaaagatt tagtagttat atataaaaaa agcaataatt caaatgaaat ggtagtcgta
    30841 gtttctgata aaaatagcca ctatataaca aagccaatac cagcacctat agagaatcaa
    30901 acgataacct ttaaaaatat tgatgataaa gcaccaatag aagtaattgt atcagggtct
    30961 aaaaatggta atgtaggata tgctatttac agagtagagg gtaaaaaatt tgttgattta
    31021 tttggcgaag atatggacaa atgttgctaa aaataaaaat aatacataaa ggtgggaaat
    31081 ttatatgaaa ttatctaaga agattcaagc attaatctta tttggtgtaa tgggtacatc
    31141 tatattaaca ggatgtagta gtaaaccaaa agaaaaagaa gaagcaaaaa ctggaaaaga
    31201 tgattataca ataacagtag gttattataa ttgtgaccat atgactgcgg gaccagtagc
    31261 agaatcggca ggaatatata aagatttagg tcttaatgta aaaactgttg gaaatggtaa
    31321 agttcctgaa gctatggcag caggaaaaat ggatgcaggt tacataggaa ctaaggggtt
    31381 agttggagca atacctaagg gttcgccaat aacaatagca gctaacaacc atactggtgg
    31441 ttctgaatat ttaatagttt caaaagatat aaaagaacct aaagatttaa taggtaaaaa
    31501 aattgcaaca gatatgagtg atttcttatg gacaagtgat tatggtccag aaacaggtct
    31561 accaactgac ccatcaaaat atgaagttgt aaatatggat tcagacaaag ataaatattt
    31621 agctcttaaa actgggaaaa ttcaagcttt tacatcttgt gacccttggg gttctgtagc
    31681 tgaaaatgac ggtgcaggaa aaataatagc atctactcaa tataaagaaa aagctaatgg
    31741 caaagaatat aactgttgtt cattctcatt aaacaaaaac tttataaaag aacatccaga
    31801 tttagcaaaa aaattggttc tagcacatac aaaagcaata gaatatatat atacaaatcc
    31861 agctgaagca gctaaaatat ttgcaaaata ttataatgta gaagaagaag ttgcacttag
    31921 aactatctat aagaagactg ttggagaagg tagaactctt acttggaaag ttacaggtga
    31981 agaatataaa aataatttac aaatgtataa agatttaaag gctttagatg atatacctaa
    32041 atatgaagat acgattgata caagcttatt ggactcttgt ggagctgatg attttgacaa
    32101 atttataaaa gaaaaagtta acccagagtt tcctgaaggt atgagttatg aagactggaa
    32161 agcaaaggta ttataaataa atggagaata tgaaaaatat aataatactt tttatcatta
    32221 ttttgggaag tatatttata atatttttta attttgaaga taaagaagaa ataaaaggaa
    32281 aattaagaat aggggtatct gatgatacct ctggttttgt aataaattat atggtaaata
    32341 gagactactt tgaaaatata aaagtaagtg atataatgga tatttttaca attaatgatt
    32401 gctgagcaag tacaatgcag tgggctctga gttcagagga aatagatata gcaatcatat
    32461 gtaaagatgc tgcaaaacaa tatgtaaatg taaatagtgg atttgaagtt gttggtactg
    32521 tagttcaaaa ttctgatata tttctattaa gtgataataa tcctgaaaag ataggagtca
    32581 ttcaaaatag agattaccag tcagaattgg ttaaaaaata ctacaagaat gtggaagtag
    32641 ctcccttatt agggactgca ctaacatatg gattagaaag taatttagta gatggtgttg
    32701 taatagattg cataaagtca attgggttag agggtaaaag aaaatctaca actaaattag
    32761 gagattatga tacctatgta ttagttgtaa ataaagagtt taaaaaaagt aaagcatata
    32821 gtgattttat aacactttac aataaaagtg ttgatgcttt aaagaataaa gctacattta
    32881 agaaagtatt aaaagagtac aggaatataa gaaatataga tatggaggaa ataagcaatt
    32941 ggaaattaaa atttctaaag ataaaagcga tagattaact aagaaaaaaa ctgatggtag
    33001 tatggatatt ttatataaaa taatactatt agttattata tttttagtct ggcattttgc
    33061 agcaaaagat atagggagtt ctttgttact tccaatgcca gtagatgtaa taaaaggttt
    33121 ctttttctgt gtgacagatg cagagacagt cactaatctt tttataacat tgcagagagt
    33181 acttaaaggt tttatgtatg cattattgtt tgggcttcca ataggattta ttatgggatt
    33241 ttctaaaact tttgaaaggg ttttatctcc agtagtagat tctgtaaggc aagttccaat
    33301 aatggcatgg gttcctctta ctatagtatg gtttggtata ggagatggtc caacaatatt
    33361 tttaatagct ttttcagggg ttttccctat aattttaaat actattcaag gagtaagagc
    33421 aatatcaaag gattattata atgcagctag aagtatggga gcatcgccaa ttgtgatatt
    33481 tacaaatgta attgttcccg catctcttcc agatatacta actggttcaa ggattgctat
    33541 aagtacagga tggatgtctg ttatctgagc cgagtttata gctacgagtg ccggtctcgg
    33601 ttactcaatg gtacaagctc aaacattaat gcatacagat gtattaattg ggcttatgat
    33661 atttgcagct ttaataggat ttataataga tagggtatta aagtttataa ataaaatcct
    33721 ttgtagatgg aggtttgcag attaatgaag ttaagtgtaa gggatataaa taagacattt
    33781 gtaaataata gagtacatac aaaggtttta gaagatataa gtatggatat agatgatgga
    33841 caatttgtct gtcttttagg accatcaggt tgtggaaaaa caactttact tactataata
    33901 ggtgggtttc aaaaatcaga acgtggagat gtttttataa atgataaaag agttaaaaaa
    33961 ccgggcatag atagagcttt tatatttcaa aattatgctt tatttccttg gaaaactata
    34021 agaggtaatg ttctatttcc tatgaaacag cagaaaatac caaaagaaaa aagagaagaa
    34081 atgctagaag aacttttggt tatgtcagac ttgaaaggaa aagaaaaact gtttccgcat
    34141 caattatctg gaggaatgaa acaaagagtg gccatgataa gagctttagc atgtaatcca
    34201 gaggtattac taatggatga accattagga gctgtagatt ttcaaatgag acaaaattta
    34261 caggaagagc tagaacgaat atggataaag aagaaaataa ctgcattaat ggtaactcat
    34321 gatgttgatg aagctgtata tatgagtgat agagttatag taatgtcgag agataaagga
    34381 agaattattg atgatataaa tatagatatt ccaagaccta gaattagagg aagccaaaaa
    34441 tatgaagagt acaaaaacaa attaactgat actttatcaa agtgttatga agtttaaaga
    34501 ggagtagaca tgagtcaaat agaaaaatac aatagtttgg ataatacaca acagaaaata
    34561 agaatctcta ttatggatat gataatagat aaaggttcta gtgttacact tcaagaagtg
    34621 actgaatatg taagtaaaaa gttgaatata gaaaaagaat atatagaaag gacactacaa
    34681 tattttattt ataaaaatat aatggttgtt gatgggaata gtataaattt tatatatcct
    34741 gtatcagcat tgccaacaaa tcataaagta actttgagag ataatagaag tttcagtgca
    34801 atgtgtgcta tagatgctat aggaacctct tgcacattca accaagatat aaaaataaac
    34861 tctatttgta gtgctacagg taaggaaata gaagtaatta taaaaaatga aaagattgag
    34921 tatgtgaata atccaaactt aagagtgctt catataaatc ttgataagca tctaaattgg
    34981 gctgctagtt gctgaaatat aatgaatttc ttctggacga agagtgattt tgatgcttgg
    35041 acaaacgaag cgggattatc tgatgatgaa gatatatatt gtttagatat taatgaggca
    35101 atagtagaat catataaaat atttaaactc aaacaaaagg tactatcata gatatacata
    35161 tatgaaaaac taaaaatgac ctttagataa aaatgatagg taatatccat actatataaa
    35221 ttagtataga gtagggatgt gaaaagtatt taaatctaaa ggtatatttt tagttttttt
    35281 tagatgatta gatagcctta ttaagtatat atttatttat aacctttgca actccatttt
    35341 cattattagt atcagtaaca taatctgcaa tttcctttat actattacgt gcattcccca
    35401 tagccacacc aagacctgca tactttatca tatgttggtc attttcttca tcgccaacag
    35461 caatagcatt ttctataggt atatttagat tcatacataa tgttttaaga gcagttcctt
    35521 tattagtagt tttacctaaa aattctagat aaaaaggagc agaccttact atagtatatt
    35581 tattgaataa atttttaggt agttgctgta tgatttcttc caatctttct ggttcatcaa
    35641 ctatcataat tttacagatt ttaatagatt catcaatttt atctttttgt atatatttga
    35701 cttctatatt atttaatttc gcttcatgaa gtgtatattt gccaggcgtt tcatttggtg
    35761 taattaaatt tgtcattgta tttatgtgta ttttagtctt atatttttta caaacgttat
    35821 tatatataaa atcaaaatca tctaaactca tttctacatc atgtatgatt ttctcacttt
    35881 taacttcttg aataattgct ccattaaagc atataacata atcaccttca tctgttaaat
    35941 ttagttgatt tagaagttct tttacaccag gaagaggtct gcctgttgtt ataactactt
    36001 ttgccccagc cctttttgcc tcctgaatgg actcaaagac ttcaggagta atcctttttt
    36061 gtgtatttaa tattgttcca tcaatgtcta gtgcgattaa tttgtacata tcaacctcca
    36121 ataaattata tactcaaatt tcctgtgaaa acgttgacac agctagtgtt gaacaacgtt
    36181 tcagtgggaa atatggtttg ttttgtatac tattatatca agagataagt aatttataaa
    36241 gtttaataat attaattttt tgataaaaat attacttatg tgagatgaga atgtaaaaac
    36301 tttgtaatca ataattccaa aattcttaat tacaaataat ggtatcgttt gcattgttaa
    36361 tataaataaa tgtatattat atagttagaa gtttgaataa atagactgat ggtaatttgt
    36421 tatattagtt agttttgtgt tataaaatat tgtaattcca ttaatcatat gttattattc
    36481 aacatgatta taatataaag aatatttgat atatataata atttataaaa gagtattaca
    36541 tagtacatgt aaatctatat ttataaatac aataaagtaa agttgtaaag gagtgcttta
    36601 aatgaagttt tcagagttta agtatgaaag acccaataat aatagtatga aaaaagagtt
    36661 tttgagttgt gtagaagata taaataattc tcgtaattat aaagagcaac aaaaaaatat
    36721 acataagatt aatttattaa gaaataaaat agaaacgttg tcaaatatag cttcgataag
    36781 atatagtaca gacacattta ataaattcta caaagaagaa aaaaattatt gggatgaata
    36841 tatgcctttg tatgaagaat taaattcata tttttataat gccattgtaa attcaaaatt
    36901 taaatatgat ttgataaaag agtttggaga gcaatttttc acaatagtag agtattcttt
    36961 aaaaagtttt tccaaagaaa taataagtga attgcaggaa gaaaataaat tgtgttcaga
    37021 gtatactaga cttttagctt cagctgagat aatgtttgat gggaaaataa gaaatttatc
    37081 tggtatgggg aaattcatgt attctaagaa tagaaaaaca agagaattag caaacaaagc
    37141 atattataat ttctttgaag aaaatgaaac taaatttgat gacatatttg ataaattggt
    37201 taaacttaga gataagatgt ctaaaaaatt aggttttgaa gattttgtag agcttgggta
    37261 tgttagaatg atgagaagtg actacagaga atatatgata aaaaatgtta gaaaacaagt
    37321 actaaaatat gttgttccaa tggcaaatga gctttatgaa aaacaagcta aaagaattgg
    37381 tctagaatat ttaagttaca tagatgaagg cgtggaattt ttaacaggaa atgcaagttt
    37441 aaagggagat tcaagataca taattcaaaa tggtaaaagg atgtattctg aactgtcaaa
    37501 agaaacaaat gaattttttg attttatgtt agaaaatgaa cttatggatt tagaaacgaa
    37561 gaaaggaaaa ggagctggag ggtattgtac ttatatacca gattataaat caccattcat
    37621 tttttctaat tttaatcaaa ctgctgatga tatagatgtg ttaacacatg aggcaggaca
    37681 tgcatttcag ttgtatatgt ctagatggat tgatatgcca gaaattaatt ttccaacgct
    37741 tgatagttgt gaaatccatt caatgagtat ggaatttata acatggccgt ggatggattt
    37801 attttttaaa gaagatacag ataagtacaa attcactcac ttatcatctt caattaaatt
    37861 tataccttat ggagtaattg ttgatgaatt tcaacactat atttacaaaa atcctaatgt
    37921 agataagtca aaacgaaaag aaatctggag atttttagag aaaaaatact tacctcatag
    37981 aaaatatggt gataattctt ttttagagag aggttgttgg tggtttaaac aaggacatat
    38041 atttaaaaat ccgttttatt atatagatta tgtattagct caaatttgtg cgttacaatt
    38101 ttggaaaaaa atgattcaag atagagatgc aggatggaaa gattatataa atatctgtaa
    38161 agttggagga acaaaatcat ttttagatat tgtgagtatg ggaaatttgt attctccatt
    38221 tgatgatggc tgtattgagt ctattatagg tgatgttaaa tcttggtttg atgaaataaa
    38281 tgacagcaaa ttataaaaaa ttatgagaat tttattgtat aaaagtgaaa aatttaaaaa
    38341 tatataaaaa gtgattattt gttgtgaaaa tagtcttgtt tttaactaaa ttgataaaat
    38401 aaactaaaaa agatttgtac ttaaaaaaaa aagaaaatac aagaaatatg caatatcaac
    38461 atttggaaaa aaaagtaaaa atgtatacaa aatacatata aaaaaactat tgcaaatttt
    38521 atagaatgtt tatatactta agtcaacaga gatagaaaaa agctatttat agaaaacaaa
    38581 ggataaattg cttaatttta aattttctga aaaaaataat aatccggatg aagagtatgg
    38641 gagactgctt tataaaaagc gaccgaaggg acaagtttaa tcttacttac ccaaaagatt
    38701 agatgaaatt ctcaggtaaa ggtgactgta cttggacggg gctctgaaaa tgattttaac
    38761 agggaagaca aattgggaga tttgtttttc ctgtttttta tttatcaagt aataaataaa
    38821 agtttgaaag agagtaaaaa aatgataata attacgaata atccaaaagt aaaagaagaa
    38881 gttcaaggca gagaagtttt gtttaaagac acaacttata ttggaatctt agaagcaagt
    38941 agagatttga tacatgaagg ttatgaactt ttatctcatc cactctatgg gagtgtaaag
    39001 ccaaatgaaa caccttacag gactgttata ctaaagaaag gaaatcgttt ggatataaac
    39061 tctttaacct taattgaaga agcaatcatc actgcaagta aatttcagaa taataaaaag
    39121 actccaaaat ggacagaaag tgttcaagat gattttagag taattgatta tgatatattt
    39181 tataatacaa tacaaagaat gcagtatgaa taaaaaaatt tgttaaaaag ttattaaaac
    39241 agcctaaata ttaaatctaa tttaatatta aataaaatga gaaatttaat tggggaggat
    39301 aagtcaaaat ggaaaatgtg tatgacttag taataattgg ttcaggacca gcagggcttg
    39361 cagcaggtct ttatggagca agagcaaagt taaaaactct aatcctagaa aaagacaaga
    39421 ctggtggaca aattgtaata acacatgaaa ttgcaaatta tccagggtca gttccaaatg
    39481 caacaggacc aagtttaata gctagaatgg ttgaacagtg taaagagttt ggagcagaaa
    39541 tgctaagaga caacattgtt gatactgagc tagatggaga tataaaagtt ttaaaagggg
    39601 aaaaggcaga atatagagca aaagcagtaa taataggaac aggagcaaca ccaagaaaga
    39661 ttggttgtcc tggagaaaaa gaacttactg gtaaaggggt ttcatattgt gcaacttgtg
    39721 atgcagattt ctttgaagat tttgaagtat ttgttgtagg tggaggagac agtgcattag
    39781 aagaagcaat gtatttaact aaatttgcta gaaaagtaac aattgtacat agaagacaag
    39841 gatttagatg tgctaagagt gttgaagaaa aagcaaaagc taatccaaag atagagtttt
    39901 tattagatac agtaattgaa gaaatcaaag gtgatggaat attagaatca gttgtattta
    39961 aaaataaagt tactggagaa actcatgaat actttgcaga tgaagaagat ggaacaatgg
    40021 gagtatttgt gtttgttgga ttagatgctc aaactgattt attcaaaggt aaagttgata
    40081 tggatgaaaa aggttacata ataactgatg aagatatgag aactaacata ccaggcgtat
    40141 ttgcagcagg agattgtaga tctaagactc taagacaggt tgtaactgca actaatgatg
    40201 gagcaattgc atctatagta gctgagaaat acattgatga aaaatttggg aactagaatc
    40261 tgtaaattaa gaaatagtgt ctgtaaattt aatgaataat atttaaaatt aaaattaata
    40321 tttaaaatta aaataaaaat ttcaaggggg aataagaaaa tgttagattt agataaggct
    40381 acatttgaag aagaagtttt aaatgcagaa ggttttgtat ttgttgattt ttggagtgaa
    40441 ggttgtgagc cttgtaaagc tttaatgcca gatgttcata aattagctga gacttatggg
    40501 gataaaataa aattctgtaa gatggataca acaaaagcta gaagattagc tataaaacaa
    40561 aaagtattag gtcttccaac tatggctata tacaaagatg gagaaaaagt agacgaagtt
    40621 actaaggatg atgctacagt tcctaatata gaaaacatga ttaaaaaata tctttaatat
    40681 gttgataaat tattaacatt aaaagaaaaa atctattttt atctgaagat aagaagaaaa
    40741 aggtttttat gtccaacttt gttaaaaaaa taattttaaa taaaataatt tttttacaat
    40801 aaatattttt tagtaataaa ataaagattt aaggcataaa aacacaataa tatatcttta
    40861 aaaaaataag ataaattgta aaatgatata attttgagaa aaactcaaat gcatatacac
    40921 aaattaaata acaggaggtg caagtatgcg tcttgaatta gggaaaatct ttataaaaga
    40981 tattcaattt ggtgatgtaa cagaagtaaa agatggagta ttattcatca ataagcaaga
    41041 gatgctacaa gaaattggtg gagatgagca tattaaatct atagatatag aattagctcg
    41101 tccaggtgaa agcgtaagaa taacacctgt aaaagatgtt attgagccaa gagtaaaagt
    41161 tgaaggtaat gggggaatct tccctggtat catgtctaaa gttgacactg taggagaagg
    41221 aaaaactcat gctttaaaag gtgtagctgt tgtaactact ggaaaaatag taggtttcca
    41281 agaaggtata atagacatga ctggagaagg agctaagtat actccatttt ctaaattaaa
    41341 taatgtagta gtaatagctg aacctattga tggtttaaaa caatacgctc atgaaaaagc
    41401 tgttagaatg ataggattca aagcagcaat gtacttagga gaagtagcaa gaaatcttac
    41461 tccagatgaa gtttcagtat atgaaactaa acctcttctt gaatcaataa aagaatatcc
    41521 agagcttcca aaagtaggat atgtttacat gcttcagact caaggtttat tacatgatac
    41581 ttatgtatat ggagtagatg caaaacaaat agtaccaact ttattatatc caacagaatt
    41641 aatggacgga gcaattgtaa gtggtaactg tgtttctgca tgtgacaaaa acccaagtta
    41701 tgttcatata aacaatgggg ttgttgaaga cttatatgca agacatggta aagatataaa
    41761 ctttgtaggt gtaattataa ctaatgaaaa tgtttaccta gcagataaag aaagatcttc
    41821 aaactggact tctaaattat gtaaatattt aggattagat gcagttatag tttcacaaga
    41881 aggttttgga aatcctgata ctgaccttat aatgaactgt aagaagatag aaatgcaagg
    41941 tgttaaaaca gttatagtta cagatgaata tgctggacgt gatggaggtt ctcaatcact
    42001 tgcagatgca gatgtaagag ctgatgctgt tgtaacaggt ggaaatgcca accaagttgt
    42061 agttcttcct aagttagata aagttattgg acatttagaa gtagtagatg taatagctgg
    42121 tggttctgat ggaagtttaa gagctgatgg aactattgaa gttgaaatcc aagctataac
    42181 aggtgcaact aatgaaacag gatttggtca tttaactgct aaaggatatt aagaagtatt
    42241 ttattaaacg attgagtaat gttaataaaa catattatag ataattataa taagtgttat
    42301 agatatataa aaatatatta gaaatataat aaggaggatt attatgagtt tacttagtaa
    42361 taaaaaggtt cttataatag gtgaccgtga tggtatacca ggacctgcga tagaagaatg
    42421 tgtaaaaaca gtagaaggag cagaggttgt tttctcatct acagaatgct ttgtctgaac
    42481 agctgctggg gctatggact tagaaaatca aaacagagtt aaagatgctg ctgataaatt
    42541 cggagctgaa aatgttgtga ttttactagg tgctgctgaa gccgaagctg caggtcttgc
    42601 agccgaaaca gtaactgctg gagatccaac tttcgctgga ccacttgctg gagttgcctt
    42661 aggattaagt gtttaccatg ttgttgagga accaataaaa tcattatttg atgaaagtgt
    42721 atatgaagac caaataagta tgatggaaat ggttttagaa gttgaagaaa tagaagaaga
    42781 aatgtctggt ataagagaag aattttgtaa attttaatgc ctaaaagcaa aaggggtgaa
    42841 actaagagat gggaaaacta aaagcagtac attatattaa tcagttcttt gctggtatag
    42901 gtggagaaga aaaagctgat actaagccac atgtggcaga aactttacct ccaataagtt
    42961 tacaacttga taaattatta ggtgaagata ttgaaatagt tggaacagta gtttgtggag
    43021 atagctattt caatgagaat atagatagtg caagtgaaga agttttatca atggtaaaag
    43081 gttttgaacc acaacttttc atagctggtc ctgcatttaa tgctggtaga tatggggttg
    43141 ctgctggaac aataactaaa gttgtaaaag atgctttgaa tataccagct ttaacaggta
    43201 tgtatgttga aaatccagga gcagatatgt tcaaaaagga tgtttatgta gtagaaactt
    43261 ctgattctgc agcaggtatg agaaaggcac ttcctaagat agctaaactt gcagtaaaac
    43321 ttgctaatgg agaagaaatt ggaactccta aagatgaagg atacatagct agaggaataa
    43381 gagttaacta cttccatgaa gacagaggtt ctaagagagc tgttgacatg ttagttaaga
    43441 aaataaaagg tgaaccattt gaaactgaat acccaatgcc aaactttgat agagttgacc
    43501 caagtaaagc tgtaaaagat ttatcaaaat gtaaaatagc tttagttact tctggtggta
    43561 tagttccaaa aggaaatcca gatagaatag agtcttcttc agcttctaaa tatggaactt
    43621 attctatagc aggagttatg gatttaacag aagagactta tgaaactgca catggtggat
    43681 atgacccagt gtatgcaaat ttagatgcag atagagtatt acctgttgat gttcttagag
    43741 atttagaaaa agaaggtgta attggaaaat tacatgagac tttctataca actgtaggta
    43801 atggtacatc tgttgcaaac tctaaaaaat atgcttctga aattggagca gcattagtgg
    43861 ctgatggtgt agatgcagta atattaactt ctacatgagg tacttgtact cgttgcggtg
    43921 caacgatggt aaaagaaata gaaaaaactg gacttccagt agttcatatg tgtacagtag
    43981 tacctatttc attaacagta ggggctaata gaatagttcc aactatagca atacctcatc
    44041 cacttggaaa tccagcgctt gaccctacag aagaaaaagc cctaagaaga ggccttgtag
    44101 aaaaagcatt aaatgcttta actacagaag tagatggtca aacagtattt gaaaaataaa
    44161 aataacacac acatatatta tatagataaa aatataaaca cacactaaaa ataaaaaata
    44221 actatacaca aaaaaaataa tatagatttc atgaatggat aaattggagt tattcattca
    44281 tgaaatctta aaaaatgcca aaatacataa acaataatag aatcaaatat acaataaaat
    44341 acaatgatta gagcttttaa taagtttaat aagattaaaa aataagtgtt cataaaattt
    44401 atggaggtgc acaaaatgac ttatccagtt ttaaaagggg caggctatgt acttattcat
    44461 actccagata tgatagtgca aaatggaagt acttgtacag ttgaaagagc aacaaatcca
    44521 gattcagaat ttttaaaaga agtaagtaat catataagaa gttatgaaga tgtagttaac
    44581 tacatgccaa atcaagttta tataggaaat agaagaccag aagaattaag agatttacca
    44641 atgccatggt gtgaacaaaa gattgaggga actagaaatg gtaagtttgg agaaataatg
    44701 cctcaagatg agttcatagc tttaatgcaa ataagtgatg catttgattt agtaaaatta
    44761 tcacaagaat ttattgatga agtaaagcca aaaatcgaaa ataactaccc tgaaattgca
    44821 ccatttgtag gtaaattaaa gggtgatgat atagaagaag gtaaagaatt agtagcaaca
    44881 cacatagctg aaggattata ccatgatgga aaatttgttg gttatgtaaa aagagcacat
    44941 gatgtagatg ttaacttaaa tgcccataca atgtttgaaa atctagtagt aaaagcatct
    45001 ggagttttat ctgctattca aatgctaaga catagcaaaa tagaccctgc tgaaatagat
    45061 tatgttattg agtgttcaga agaagcttgt ggagatataa accaaagagg tggaggaaac
    45121 tttgctaaat caatagctga gatagcagga cttcaaaatg caacgggttc tgacacaaga
    45181 ggattttgtg cagcaccaac tcatgcatta attcaagcag cagctttagt aaaagctggc
    45241 atacataaaa atgtaatggt agtagcaggt ggagcaagtg ctaaacttgg aatgaatgct
    45301 aaagaccatg ttaaaaaagg tcttcctgta cttgaagatg ttgttggagg atttgcagta
    45361 cttgtatctg aaaatgatgg tgtaaatcca gttataagaa ctgatttaac aggtaagcat
    45421 actgttggaa ctggttcttc accacaagca gttatgacag cacttataac ttcaggtctt
    45481 gatagagcta atttaaaaat aacagatgtt gatgtgtatt cagttgaaat gcaaaaccca
    45541 gatataacta agccagcagg agcaggagat gttccagaag caaactacaa aatgataggg
    45601 gcacttgctg ttaaacgtgg agacttagaa aagaaagaat tgaaagattt tgtttctaac
    45661 aaaggattac caggatgggc accaactcaa ggacatatac catcaggagc tccttatata
    45721 ggatttttaa tagatgattt aactacagga aatagaaata gagctatgat agttggaaaa
    45781 ggtagtttat tcttaggaag aatgactaac ttatttgatg gagtatcttt tatagctgaa
    45841 agaaatacag gtgttactga agagacttca ggaatatcta aggatgaaat taagaagata
    45901 atagctgaat ctatgaaaaa actagcatta gatatgttag aagaataggg gtgaggatat
    45961 gtcaagaaaa gtaatcgcag atgtattctt agaggtagct aatgcaatag aaagcggcga
    46021 atttggcaaa aaagtaaaaa ttggtgttac tacacttgga agtgaacatg gtgtagaaaa
    46081 catggttaat ggtgcacaat tagcaaaatc taatttattt gatattgtgc ttattggacc
    46141 aaaagtggaa actgaccttg aagtagttga agttaatgat gaaaaagaaa tgcatgcaaa
    46201 aatggaagaa ttattagatt caggatatat tgatgcttgt gttactatgc attataattt
    46261 tccaataggt gtatctacag taggtagagt aataactcca gcaaaaggaa aagaaatgat
    46321 acttgcaaca acaacaggaa caagtgctac taatagaata gaggcaatgg taagaaatgc
    46381 catttatggt attgctacag ctaaatcaat gggtaacaaa tgcccaaaag ttggaatact
    46441 taatgttgat ggagcaagac aagttgagaa gtgcttaaaa gaattaaaag ataatggata
    46501 tgacatggag tttgcggatt caattagagc agatggtgga tgtgtaatga gaggtaatga
    46561 tttacttgta ggtgcacctg atgttatggt tactgataca ttatctggaa atatatttat
    46621 gaaagtattt tcttcatata ctacaggtgg agattatgaa gctcaaggct ttggatacgg
    46681 acctggagtt ggagaggact atgatagaaa ggtacttata gtatcaagag catcaggttc
    46741 tccggtagta gcaaatgctt taaaatacgc ttatgatgtt gtaaagggag atataagtaa
    46801 tgttgcaaga aatgaatttg caaaggttaa aaaagcaaaa tttgatgaca ttatatcctc
    46861 tcttactaaa aaagaagtta aagttgaaaa agtagaagtt aaaatgccag ataaagaaat
    46921 tgttactcgt caaatagctg gtgttgatat aatggattta gaagatgcag tatctgagtt
    46981 atggaaaaac ggaatctatg ctgaaagtgg tatgggttgt acaggtccaa tagttttagt
    47041 aaatgaagct aaaggagact tagcagttga aactttagtt aaagctggat atactgcaaa
    47101 ataagtacat tttttatatg tagataagaa catatagtta taattttatt gattataatt
    47161 atatgttctt tttattttat atcttgtcaa tatttatata ttaacacaat ccatttattt
    47221 gattctctag ctaatttatt atatttattc aattaaaatt aagctttcta actaaataaa
    47281 aactaatgaa gtattaaaat gaaattgata aaatatgaaa aaattttagg aataaagtat
    47341 ctgttagata aaaataagat taattagtga tataatataa ttaagataaa atttattatt
    47401 tggaggtaaa atcatgagca gagtaaaaaa tgtagtagaa ttgttggaaa ctaaaggtgt
    47461 tgatgcacta tatctaacaa agaaaactaa tgtaaactat ataagtggtt ttcctgatga
    47521 agaagcatat gcagtgattt gcaaagatgg aaacttttta gttactgata gtagatatat
    47581 ggagcttgca gaaaaggttt gcaaagattt tgaaattata aattggcata attttgatag
    47641 aagtgtggca aaggcagtta aaagtgtatg tgataaagtg ggtataaaga aacttgggtt
    47701 tgaaagaact aatatagtgt ttgataaata tgaagaactt aaaaatctga ttgagaagga
    47761 taatggagaa ttaataccta cagaaaatat tgtagagact ttgagatatg taaaagacaa
    47821 agatgaaatc aaaaatacaa gaaaagcttg tgaaatagcg gataaggcat tagaagaatt
    47881 gattccacat ataaaagctg gagttagcga aattgaactg gctacaaagt tagagtactt
    47941 tatgaaaatg aacggagcac aaaatatagg gtttgaaact atactgatat caggagcaaa
    48001 gacttcattg cttcatggta agcctagtga taagattata gaaaaaggtg attttgtact
    48061 tatagactat ggtgctatgt ataatggcta tatatctgat acaactagaa cttttatagt
    48121 tggaggagct tctgaaaagc aattagaaat atataattta gttaaggaag ctcaaaatgt
    48181 aggggttgag aacatgaaag ctggtgtaca tgcgacaatt ccagatgctg agataagaaa
    48241 agttgtcaaa aaatatgaag actattacta tcaaggtata ggacatggag tcggtagaga
    48301 tgttcatgaa gaacctttca ttggtaatta tggtgataaa atcatagaag agggatgtat
    48361 aataacaatg gaaccaggta tttatttccc tggatggggt ggagttagaa tagaagatac
    48421 tgttttgatt actaaaaatg gtccagaaag acttactaaa ttccctaaag atttgatgat
    48481 tttagacaaa taatttaatt tatatatatt tttttacata aaatataaca taatctcact
    48541 attaagctct atttacatat tatagtaaag agggcttaat tttattgtga gaggtgatag
    48601 tatatatgta taaaaaacat aaatttataa aaaatataaa aaaagcctgg tataaaatca
    48661 aattaattga tagatgcctt ataattgtaa tggcaatatt aatgtttcaa tctatatata
    48721 atttatttgt taatgaagta aattcacaag atactacaac tattgatgta gtagtaagaa
    48781 ccacttcagc agctatattt gggtattttt taagtgctaa ttttataaag agacctttaa
    48841 ggaagtatac aaatactgat gtatcttcaa atctttttat agataataat ttatccccaa
    48901 aaggtcaaga gtctagtcaa aataatataa tgaatgtcaa aaataccatt ggatttactt
    48961 cagaagctga taattatgaa aagaaaatac ctattaataa taatgaaggt tttgaagaag
    49021 gagaaactag tgaattgcaa attattatag ctactgtaat ttgtatagta gcattaacag
    49081 tactttttgt tgtaagaaat tttacaacta caacatcagc ttctttaggt actatttcac
    49141 agatgagaga ttttgtctca ggatgcgtgg gttttttgct aggttgtcca agtaaacctg
    49201 attaaaaaag tattatcaat aaaaggtatt ttaaaaagta tcagtataat aatatttaga
    49261 tttaaatgta tacaattata attctataac attctatatt gtatttttat actgatactc
    49321 taaactatac tatttattaa aatattttaa cactgtattt aaacaaaata ttatatctgt
    49381 ataatataaa tttagtttat atgaatagat gccatatact caataaaaag tttcatacta
    49441 tgagatatgt attgatttct tctccaaaga accccaatat ttgcagtaat tgcacgttct
    49501 aatggtattg aacagagatt ttctgtattt tgaaatattt ctttatacaa tattgttgaa
    49561 gccaagtcat tttctagtaa ataacgtatg gtagaaagtt gatttgagtg taaaattata
    49621 tttggcttag ctttttcaag tctttttgta ataatcttat agtgataaga accttcagat
    49681 aagattacaa aaggtacatt ttttaacata taattcgata taatgggatg ttttgccaat
    49741 tcatttttgg gatttgtaac taagtataat tctgttttat agattgtctt tgaatctata
    49801 tcatcataaa tatcactgtc aattatacca atacaaaaat caagtgtaga ttcttcaatc
    49861 attttagctc caacaaatgt tggaacttca aaaattttaa gctctatatc tggataaatt
    49921 acattaaatc taggaagtat ttttgaaagc aaaaacgtac ctaaaactgt aggaatacct
    49981 attttgagag aagcttttct cttttttcct aaatcaagtg cgtcacattg aaaatcctca
    50041 aattgtttta taaaatgttt tgacttgtct aaaaaaattt ttccttcagg cgttaactct
    50101 attttattac ctattctgta aaaaagttca aagccaagtt ctttttctaa ttctttaatt
    50161 gctaatgtta tggatggttg agaaatatga atactttccg cagccttagt catgttttta
    50221 tatttacaga cagtttgaaa atagtataaa tagtttatat tcatttggta ttagttcctt
    50281 tcatttacat attagtgaca agtatataat taacaatagc ataagttttg tatattgttg
    50341 taaaaaaata gaatagtttt aaactatcat agcataagtt tttgatattt tcaatctatt
    50401 aagaatagtg ctattattaa attaacaaaa gagaatagct ggtatggttt agagtaaatc
    50461 aatctatatt acagttatat caacgaatat taaaaaatta tctattaaaa aataaaaatt
    50521 atttttacaa ttaaattgtt aattaaatca taaagaaaaa agtgatatta acaagataaa
    50581 atttttttaa tcagaaatgt taatttaata acaaaataga gtattgggga gaaaggagaa
    50641 atatattttt taataatatt tgttaattta ataacgaaaa atgaaaggga gtgatttagt
    50701 gaagtttgaa ttgatggatt ttttaatgaa tccttttgtc cttatgtttg ctgcagtaat
    50761 tacaggaatt ttatttggaa aaattaaatt tgggaagttt aattttgggg tatcaggagc
    50821 attatttaca ggattattta ttggatggct tgcatatagc ttggggaatc taataatagc
    50881 aaaaggggaa acagcagcag gatataaggc agcaactgta atgatgggga atggaattat
    50941 ttcttctgac ttctttgatt tctttttaat aatatttgtt gcagcagttg gtctattggc
    51001 agcaaaagat atgaaagctg tattaaagaa gtatggagca agatttgtaa ttttaggagt
    51061 tcttataact tttataggtg gctctatgac ttatgcaatg actttactat caagtgataa
    51121 aggaagtagt gcttatgaag tttctggcgt ttacacagga gcattaacaa gttcgcctgg
    51181 attagctgct gctttagaaa cagctggtaa acatgcagaa gatgtatcaa aagaatttga
    51241 aaaagcttca ataaaagata aaaaagaaat tttaaaagta gtcgacccag aaggcaaatt
    51301 ggatgtgaat acaactacat cactgactca agagcaaata gataagtata ttgcatatgc
    51361 tgaagctggt gttggtatag gtcatgcagt cgcatatcct tttggagttt taatagtaat
    51421 cttaggtgta aatttccttc caaaattatt taggatggac ctaaaagaag aaagaagaaa
    51481 atatgagaag gaaatgaagg aagcaagaga tagtgtttct ggtaaaacga taccagaagt
    51541 tccatttaat ataataacat ttttcttgac atgtttagct ggatacttag ttggaggaat
    51601 acatgtattt atgggaccac tagggtactt cacactaggt gcaacaggag gttcactaat
    51661 tgtatctcta gttcttggat atataggtaa gataggggta gtaaatttca gaatggaaga
    51721 aaaggtttta aatattttaa aacaaatagg gctagtattt ttcttagcaa tagttggatt
    51781 aagatatggt ggaaaagtag ttgattcaat tatgacatct ggtatgcacc tagccttagt
    51841 agcaatagca gtaggtgtta cagctatgat gataggattc ttagttggca aatacgtatt
    51901 taaattaaat tggattttat tatctggagc tgtctgtggt ggtatgacat caacaccagg
    51961 tcttggagct gctgttgatg ctcttgatag tgatgaccca gcagcaggtt atggtgctac
    52021 gtatccattt gcattattaa ctaaagttat attggttata gttttacaca aacttccaat
    52081 gtaaataaga ttttatatgg ggggatattt atgaataatg aaggagcatt tgaagaatta
    52141 aatggaagat taagaaataa agaattgtgt gatttaataa tgaatgcaga tgaagctgct
    52201 aaaattatag aggatggcat ggttattgga gttagtggat ttacaccttc aggctatcca
    52261 aaagcagtac cattagcagt ttcagaaaga gctaaaagtg gagaaaagat aaaattaacc
    52321 gtatattcag gagcatcttt aggtccagaa gttgatggag catggtcaga agcaggtata
    52381 attgaaagaa gacttcctta tcaaactaat tcaatactta gaaataatat taataaaggt
    52441 gttgttgatt atatagatat gcacctaagt cattctactc aatttttaaa ttatggaact
    52501 atacctaaag tagatgtagc tatagtagaa gcacttgcaa taactgaaga agggaatatt
    52561 ataccaacta gtgggatagg taattctcca tcttttataa aaagtgcaga taaagtaata
    52621 gtagagataa atcttgcaaa accaatggaa atggaaggta tggcagatat atatattacg
    52681 gaaaatccac caaatagaaa accaatagaa ataaatcatc ctaaggatag aattggaaca
    52741 acatatatac cttgtggttt ggataaaatt tcaggagtag taattaccaa tatgcaagat
    52801 aagacccgtc cattgggagt tgtagatgaa gcttcgaaaa aaatatcaaa taatattatt
    52861 gcttttttaa gagaagaagt aaaggcaggc agattatcaa agaatttact tcctcttcaa
    52921 tctggtgtag gaagtgtagc aaatgcagta ttatatggat tatgtgaatc tgaatttgaa
    52981 aatttaactt gttatacaga ggttgtacag gactctatgt tggatttaat aagaatgggt
    53041 aaagttacaa tggcatctac tacatccgta agtccatctc cagaaggatt aataaaattt
    53101 gaaaaagata ttgatttttt taaggataag attatattaa gacctcaaga aattagtaac
    53161 aatccagaaa tagccagaag aattggtgta attgcaatga acactgcaat tgaagttgat
    53221 atttatggaa atgtaaattc tactcacata atggggtcaa agatgatgaa tggaattgga
    53281 ggttctggtg attttgctag aaatggagca ataactatat ttagtactga gtcaattgca
    53341 aaaaatggtg atatatcatc aatagtacct atggtatctc acgtagacca cactgaacat
    53401 gatgtaatgg taattgtaac agaacaagga tatgctgatt taagaggtct cgcacctaga
    53461 gaaagagcta taaaaataat agaaaattgt gcccatccag attataaaga acaacttagg
    53521 gattatttaa atagagcttg taaaagtgga gcaaaacaaa cacctcacat attggacgaa
    53581 gctttatcat ggcatagtaa atttatgagt acaggtacaa tgaaaaaggc tgaaactttt
    53641 aaaagtgcat tataaaatat ttaataaatt ggaggtagat tttaaatgga aaaagcagtg
    53701 gaaaactttg aagatttaag taaggaatac attaatggtt atattgagag agcaagaaaa
    53761 gctcaaagag agtttgaatg ttatactcaa gaacaagtag ataaaatagt aaaaatagtt
    53821 ggaaaagtag tgtattataa tgctgaatat ttagctaaac ttgctgtaga agagactgga
    53881 atgggagtat atgaagataa ggtagctaaa aataaaagca aagcaaaagt tatatataac
    53941 aatttaaaag ataaaaaatc agttggtata attgatatag atagagaaac tggaataaca
    54001 aaggtagcta aaccagttgg agtagtagcg gcaataactc cttgtacaaa tccaatcgtt
    54061 acacctatga gcaatgcaat gtttgcactt aagggaagaa atgcaattat tatcacacct
    54121 catcataaag caattggatg tagtacaaaa actgtagaga tgattaatga agaattagaa
    54181 aaaataggag ctccagaaaa tttaatacaa atacttgacc aacaatcaag agaaaataca
    54241 agaaatttaa tttcatcagc agatgtagta attgccactg gaggaatggg aatggtaaaa
    54301 gctgcgtact caagtggaaa accagcactt ggtgtagggg caggaaatgt tcaatgtatc
    54361 atagatagag atgtagacat taaagaagca gtacctaaaa tcatagcagg aagaattttt
    54421 gataatggta tcatttgttc aggtgaacag tcagtaatag tagcagaaga aatgtttgat
    54481 aaaataatgg atgaatttaa aaataacaaa ggttttatag ttagagataa agtacaaaaa
    54541 gaagctttca gaaatgctat gtttgtaaat aaatctatga ataaagatgc agtaggtcaa
    54601 tcagttcata caattgcaaa aattgcaggt gttgagatac cagaagatac aaaaataata
    54661 gtaatagaag ctgatggacc aggagaagag gatattattg caaaagaaaa aatgtgtcca
    54721 gttatatctg catacaagta taaaagtttt gaagaaggtg tagctattgc aaaagcaaat
    54781 ttaaatgtag aaggaaaagg acatagtgta tctatacatt caaatacagt taaaaatata
    54841 gaatatgcag gagaaaatat agaagtatca agatttgtta ttaatcaatg ttgtgctact
    54901 agtgctggag gaagtttctt taatggtctt gcacctacta atactctagg ttgtggttct
    54961 tggggaaata acagcatctc tgaaaatctt gattataagc atctaattaa tatttctaga
    55021 attgcttatt atatgccaga aaatgaagtc cctacagatg aagaactttg gggataaaat
    55081 ttagacaaaa aatattcatt ctaaattaaa gtaggaatat actttaattt agaatgaatt
    55141 taagacataa attaaattta aattagttta ttggactaaa tttaaaatat taagagacat
    55201 atagaagaag gaagtattat aatttaaaat aaataaaaaa atctataaaa gagaaggagt
    55261 ggttttatta tggcattaat gacaggagct caatatattg aaagtttgag aaaattaaat
    55321 actaaggttt atatgtttgg tgaagaggtt aagaattggg ttgaccatcc tatgattaga
    55381 ccatctataa attgtgtagc agcaacttat gacttagctc atgacccaga atatgcagat
    55441 ttaatgacag ttacttcaaa tatcacaggt gaaaaaataa atagatttgg tcatcttcat
    55501 caaagtgttg atgatttgat aaaaaaagta aaaatgcaaa gactatgtgg tcaaaaaaca
    55561 gcttcttgtt tccaaagatg tgttggtatg gatgcgttta atgcagtgta ttcaacaaca
    55621 tttgagtgtg ataaagccca tggaactaat tatcatgata attttgtaaa atacttaact
    55681 tatatacaag aaaacgattt agtagttgat ggagctatga ctgaccctaa gggagataga
    55741 agtctatcac ctagtgctca acctgaccca gatatgttcc ttcatatagt agaaagaaga
    55801 gaagatggga taattgtaag aggagcaaag gcacatcaaa ctggttcaat aaattcacat
    55861 gagcacctta taatgcctac tataagtatg actgaagcag ataaagacta cgctgtatca
    55921 tttgcagttc cttcagatgc tgaaggagtg tttatgattt atggaagaca atcttgtgac
    55981 actagaaaat tagaagaagg tgcagatgtt gatttaggaa ataaggagtt tggaggtcaa
    56041 gaagctttag tagtatttga taatgtattt gttccaaatg atagaatttt cttatgtgga
    56101 gaatgggatt tctctggtat gttagtagag agatttgcag gataccatag acaaagttat
    56161 ggtggatgta aagtaggagt aggtgatgta ataataggag cagcagcttt agcagctgat
    56221 tataatggag caaacaaagc ttcacatata aaagataaac taatagaaat gactcacctt
    56281 aatgaaagct tatattgctg tggtatagca tgttcatcag aaggtcacaa aacagaagct
    56341 ggaaactatc aaatagattt acttcttgca aatgtgtgta aacaaaatgt aactagattt
    56401 ccttatgaaa tagtaagact tgcagaagat atagctggag ggcttatggt tactatgcct
    56461 tcagaaaaag actttaaatc agaccttaaa gttggaacaa gtggaatgac tattggcgaa
    56521 gtatgtaaca agtattttaa agcttcttca gtggcttcaa cagaagaaag aatgagaata
    56581 ttaagattct tagaaaatat atgccttggt tcatctgctg ttggttatag aactgagtca
    56641 atgcatgggg caggttcacc acaagctcaa agaataatga tttcaagaca aggaaacata
    56701 aatcaaaaga aagaattagc taagaaaatt gcgggaataa aaaaagagga agctttaaat
    56761 ttataaaaag ttgatatata aagggaaatt atatattaat gtgtattaat taatgaaaaa
    56821 atatgtagta taagagatag ttataaaatt atggtggttt ttagctaagt aaagaaattt
    56881 ttaataagga gaatttacac atgacctgtg gagttagatt ttgtgggggc tgtaacccta
    56941 gatacgaaag agggaaggct cttacaataa tcaaagagca cttcaatggt agggtagatt
    57001 ttagtatagc acaagagaac gtcgagtatg atttgctact tataattgga ggatgcgcaa
    57061 ctctatgcgc atcctatcaa caatataaag tgaaaaatga atgtgttaag atgtgggatt
    57121 ttagccatat agaaagagtt ataaatgtga ttgaatcagc aatttgtgaa acttaaaaaa
    57181 gctaaatggg gggatttcat tgagttggca agaattgtat caaagtaaat tatgtagtgc
    57241 tacagaagct gtaaaacaga ttaaaaacgg tgatactgta gtatttgcac attgtgtagg
    57301 tgaacctcct gcactagtag aggctatgat tgaaaatgct gaacaatata aagatgttga
    57361 gattaaacat atggtaagct tgggtagtgg tggatatact gctaagggaa tggaagctca
    57421 ttttagagta aatccaatgt ttgtaagtgg aaatgtaaga aaggcaattg aaaatggaga
    57481 tggtgatttt acacctgcat tcttccatga agtaccaaag ttgcttagag aaaaaagatt
    57541 aaaatgtgat gttgttttag cacaggtaac tccaccagat gaacatgggt attgtagctt
    57601 aggaacatca gttgattata cttatgaagc cattaaaact gctagaacag taattgttca
    57661 agtgaatgac cagtttccta gaacctatgg tgaggtagtc catgtatcag agtttgacta
    57721 tatagtggaa aaatcacaac ctttatttga actacaacct gcaaagattg gagaagtaga
    57781 agaagcaatt ggtaaaaatt gtgcttcatt aattgaagat ggttctactt tacagttagg
    57841 gattggtggg ataccagatg cagttatgtt atttttaact gataaaaagg atttagggat
    57901 tcattcagaa atgatttcag atgggacttt ggccctttat gaaaaaggtg ttataaatgg
    57961 taaatataaa aattttgata aagaaaaaat gacagttacc ttcttaatgg gtactaaaaa
    58021 attatatgac tttgcaaata ataaccctgc agtagaggta aaaccagtag actatgtgaa
    58081 tcatccagca attataatga aacaacataa gatggtttct ataaattctg ctatacaagt
    58141 tgatttaatg ggacaggtag ttgcagaggc tatgggactt agacaattta gtggtgttgg
    58201 aggtcaagtt gactttatac gtggagtgtc tatgggtgaa gatggaaagg caattatagc
    58261 tatgccttca ataactacaa aaaaagatgg tacagtaatt tcaaaaatcg tatctattgt
    58321 ggatgaaggt gcacctataa cgacatcaag aaatgatgtt gactatattg taacagaata
    58381 cggtatagca gaattaaaag gaaaatctct tagagaaaga gcaagaaatt taataaatat
    58441 agctcatcca agtgtaagag aaagtctagc agtagaattt gaaaagagat ttaaggagaa
    58501 atattaataa tagaggggtg ttaataatgg aagcacttag agtagttcca aagatatttt
    58561 actttgatac atttaaagaa tttaatgaag aatttaaaat aggaaaaaat gatttagtaa
    58621 ttactaatga gtttatatat gagccatata tgaaacctct tggaatagat acaaatttaa
    58681 tttttcaaga aaagtttgga acaggtgaac catctgatga aatgatagac tccatgacaa
    58741 aggaaatgaa gaaatacaat tttgatagaa ttattgcatt tggaggagga acaatagttg
    58801 atatatgtaa gctattagca cttgatgttc cagaaaagtc tattgattta tttgaaggag
    58861 aagtatcacc taaaaaagta aaagagttag tagtagttcc tacaacatgt ggtacaggta
    58921 gtgaagtaac aaatgtagct attgcagagt taaaatctaa acatactaaa aaggggcttg
    58981 cagtagaaga aacatatgca gactatgcag tgttaattcc agagacagta aaagggttac
    59041 cttacaaatt ctttgttaca agttcggtag atgctcttat acatgctatt gagtcttatc
    59101 tttctccaaa agcaagtcca tttacagaga tgtattctct acaagcaata aaaatgatta
    59161 tggatgggta taagaagata gttgataaag gagaagaaga gagatttaat catcttagag
    59221 actttgtact tgcatcaaat tatgcaggaa ttgcttttgg aaatgctggt tgtgcagcag
    59281 ttcatgcact atcttattca ataggtggag ctttccatgt tgcacatggt gaagcaaatt
    59341 atcagttctt tactgaagta tttaagatgt attctagaaa aaaacctaat ggaaaaatta
    59401 taaaatgtac aaaaatttta gcagatgccc ttgaatgtga ccctaactgt gatgtttatg
    59461 gagaattaga aaagttttta aataaattaa tagctaaaaa agctttgaga gaatatggaa
    59521 tggtggaaag tcagatagat gaatttacag atagtacaat agcaaatcaa caacgactac
    59581 ttgctaataa ttatgtagag cttagtagag aggaaataag agagatattt gcaaatcttt
    59641 attaatacaa ttttttattt gtatgtatag tcaacataaa taatgctaat tatatttatg
    59701 tacaaataaa aataagggaa cttaaatttt aattaaagtt aagttctctt atttttatat
    59761 ggagttaaat ataagtatat ttttaattta aaatatgctt atatttaagt ctattacttt
    59821 atttgaaaca atttgtagaa tttcaaattc cttgacagta ataagtaagt aattgtataa
    59881 tcaaactgca atatattaat aatattagtg aaaatgaaag gattataaaa tatgtataaa
    59941 tcagaaaatt tttcaaaaaa atctgtatta ataaattcat ttttaagtaa atttttaaaa
    60001 ataattggat ggggtttggt aagcttattt acattatcag ccttagtact ttcaactatt
    60061 tccattataa ttggatgggc tgtaatactt cctattcaag tatgtgcagt atttttactt
    60121 ataggaggag tttgtatttt taaaggtaag agattaggag accaaatttc tcgttataaa
    60181 aaatattgta caattataaa caatagaaat attattccag tagaacttat tgcagaaaac
    60241 acatctaaat cattaaattt tataataaaa gatgtacaaa agatgataga caaaaactac
    60301 tttataaata cttatattga taaaagaaat aatcagattg tgttaacaaa tgaagatttt
    60361 attccaccaa gatatgaaga tgtagcatat gaagtcaaag aagaagaaaa gactgatgaa
    60421 tccaatgaag ttgatacaat tataaataaa ggaatgaatt atctaacaca aataaaagaa
    60481 gctaataaaa atattaaatc agaatcaatg ggcaataaaa ttgtacaagt agaagatgtt
    60541 acaagtaaaa tatttgatgt tgtaaaacat gacccatcaa aacttactca aatacaaaaa
    60601 tttatggatt attatcttcc aactacttta aaactattaa attcatatca tacattggaa
    60661 gaacaaggaa ttgatagaga aaatataaca acaactatgg aaagtattga aaatacaatg
    60721 aatacgattg tagtagcttt tgaaaatcaa ttggactatt tgtttgaaga tgaagccatt
    60781 gatatttcta cagatattac tgttttagag aatatgttag tccaagaagg attaacgagt
    60841 ggtaaatttt aacttcaata gaaaaaatat tctgttattt ttaaacaatt aattagtcat
    60901 aaagtataaa atgtgtatta tataagttaa tcagtacttt atgaaggaag aggagagaaa
    60961 gatacaatga ataatttaga tgatatacca gttatgccaa ctttgacact tgacccattt
    61021 ggagaagaat caaacactaa tgatatagat aattctgact tattaatgaa aaaggatgaa
    61081 aaagacccag aagaagaaaa actgtctgaa tctgaacgca agatggtaaa ggaatttgcg
    61141 gaaaaaatag atattacaaa tacaaatatg attttgcaat atggagctgg tgctcaaaaa
    61201 aaggtagcaa gtttttctga aacagcttta aagagtgtaa aaacaagaga tttaggagaa
    61261 gttggagata tgcttacaaa tctagttact gatttaaaag cattttcagc agatgaaaaa
    61321 gaacaaagtg gttttttagg aatttttaaa aaggcaaata ataaaatttc aaatttaaaa
    61381 actaagtatg atagtgcaga ggtaaatgtg gataaagtaa gcaaagagct tcaaaagcat
    61441 caggttaaaa tattgaaaga tatagcaatg cttgataaga tgtatgaatt gaacttagct
    61501 tactcaaaag agcttactat gtatattata gcaggaaaac aaaaattaaa ggatatgaaa
    61561 gaatatgaga tgccaaagtt gagagaaaaa gctcgtttat ctggttcaac agaagatgct
    61621 caatctgtaa atgatatggt ttcactttgt gacagatttg aaaagaagat tcatgactta
    61681 gaattaacta gaatggtatc gcttcaaatg gctcctcaga taagattggt tcaaaatagt
    61741 aataatctga tggcagaaaa gattcaatca actatagtaa ataccattcc attatggaaa
    61801 aatcaaatag tgcttgctct tggaatttct cacttaaatc aagctatgaa agcacagcgt
    61861 gaagttagta atatgacaaa tgagctttta ttaaagaatg cagaaacttt gaagatggga
    61921 acaatagaaa cagcaaaaga atcagaaaga ggaattgtag atatagacac aattaagaaa
    61981 acgaatcaat ctctaatatc tactattgat gaggtagtta aaatacaaca tgatggtaga
    62041 ataaagagac aagaagcaga agttgaatta tcaaaaatag aaaatgaact taaaagtaag
    62101 cttcttgaat ttacagttaa ataaaaatta tactaatata aaaagagact gtctcaaaat
    62161 agagataagt ctctttttca ttgtttaaat gattaaagta tatttatatt ataaatttct
    62221 attatctttt aacataacat catgagctcc accttcaact atactagtag aagatacaag
    62281 tgtaagttta gcattttttt gaagttcagg aatgctaagt gctccacagt tacacatagt
    62341 agaacgaact ttacttaaag aaagagttac attgtctttc aaagaaccag cataaggcac
    62401 ataagagtca acaccttctt caaaagaaag tttcttatct ccaccaaggt catatctttg
    62461 ccagtttcta gcacgagcag aaccttctcc ccaatactct ttcatataac taccatttat
    62521 attaactttg ttagttggac tctcatcaaa acgagagaag tatctaccaa gcattataaa
    62581 atctgcaccc atagctaaag ctaaagttat atgatggtca taaacgatac caccatcaga
    62641 gcaaattgga atataaatac ctgttttttc aaagtattcg tctctagctt gagcaacttc
    62701 aattatagaa gtagcttgtc cacgtcctat acctttttgt tcacgagtta tacatataga
    62761 accaccacca ataccaactt taacgaagtc agcaccagct tcagctaggt aaaggaatcc
    62821 ttcgcggtca actacatttc cagctcctac cttaactgta tcaccatatt tttcacgaat
    62881 gaaatcaagt gttatttttt gccactcaga aaaaccttct gaagaatcta tacataaaac
    62941 atcagcacca gcttcaacta aagcaggaac acgttcagca aagtctctag tattaatacc
    63001 agctccaact acatatctct tagaagaatc taaaagttca agtggatttt ctttatgaga
    63061 agagtaatct ttacggaata ccatatacat aagattacca ttatcatcaa gcacaggaag
    63121 agaattaagt ttgtggtccc atataatatt gtttgcttcc tttaaagtaa catctttgtt
    63181 agcataaact atagatgaca taggagtcat aaattcacta actttagtat ctaaatccat
    63241 acgacttata cgataatcac gacttgcaac aatacccaat aatttaccag ttgaagttcc
    63301 atcttcagta acagctactg tagaatgtcc agttttttct tttaagtcaa gtatgtcttt
    63361 taatgtgtta tcaggtttaa tatttgaatc acttacaaca aaaccagctt tgtgggattt
    63421 aacacgtgct accatagcag cttcattttc aatagtttga gaaccgtata taaatgaaat
    63481 accaccttct ttagcaagtg caatagccat tttgtcatca gaaacagatt gcataatagc
    63541 agaagtcaaa ggtatattca tataaatatc tgcttcctcg ccctttttaa atttagtaac
    63601 aggtgttttt aaacttacat tagcaggtat acaatcagta gaagagaaac ctggtacaag
    63661 aaggtattca ctgaaagtat gtgatggtgt atcaaaataa aacgccattt tttaatcact
    63721 ccttatattt ttatactttt tataattgat agtattaatt ataacttatt ctttaatttt
    63781 attaaagtat tttgtcaaat attgagattt ttgaaaaatt taaactattt taattaaatt
    63841 tgtttaatat atattgcctt atagggtaaa gttgtatatt aaataatgtt tagtgtttaa
    63901 tagtagctaa tttaaaatta atctttagtg attcatataa ttacatttgt atagtttaca
    63961 ttgataatat tactagagag tgcataaacc tcaaaaatac agataaatta aatctatatt
    64021 agtatatcca aaagtacatt taataaattt atttaactga attattattt tcatttctat
    64081 taaatttaaa tattttataa aaatagtatt atttacaaaa tcatatactc caaaatacta
    64141 cataaataaa attaaacaaa aactaaaatg acaaatgtca ttatctaaag tgacatagaa
    64201 acggtttctt aaagttgtta ctataaaata taaactctat aataaaagta taacaaaagg
    64261 gaatcatatc gatatagaat ataattcaag aggaggtaaa attatgagta gttctaatca
    64321 atcgacaata aagacatcta tacagcgaat agggaaattt ttaagtggta tggtaatgcc
    64381 aaatatagga gcttttatag catggggtct tataacagca ttatttatac caacaggatg
    64441 gatgcctaat gaaaaattga gtactatagg tgacccaatg ataaaatacc ttttaccact
    64501 attgatagct tatactggtg gtaaagcaat agcaggacaa agaggtggcg taataggtgc
    64561 agcagcagct atgggagtaa ttgttggtgc agatatacca atgtttattg gagcaatgat
    64621 aatgggacca tttgcaggat gggtaattaa gaagtttgat aaatttgtag atggaaagat
    64681 accaacagga tttgaaatgt tagtaaataa cttttcaata ggtataatag gtatgcttct
    64741 tgcaatacta ggattttatg caattggacc agcaatagta gcagggacag ctcttataga
    64801 atctggagtt caatttatag ttagcaaaag tttattgcct ctagtttcag tatttataga
    64861 acctggaaaa gtattattct taaacaatgc aataaatcat ggtatattag ggcctatagg
    64921 tatagctgag gcaaaagaag caggtaaatc tataatgttc ttactagaaa gtaaccctgg
    64981 accaggttta ggagttctat tagcatattg gatgtttagt agaggaagtg taaaacaatc
    65041 agcaccagga gctgtaataa tacatttctt tggtggtatc catgaaattt acttcccata
    65101 tattttaatg aatccagttt taatattggc tacaatggca ggtggagcag caggaatatt
    65161 gactttttca atattaggag ctgggcttgt agcagcacca tcaccaggaa gtatatttgc
    65221 acttatggca ctagctccaa agggaggatt acttccagta ttagcaggag ttgcagtggc
    65281 aacagttgta tcattcttag tggcagcacc atttgttaag agagcttcag caaatcaaag
    65341 tgaagaagac agtacttctt tagaagaagc taaagcaaaa atgagtgata tgaaatctgc
    65401 aagtaagaac tctgagaaaa atattgagga aaaacagctt gaagtaaatg agattaagaa
    65461 gattgtattt gcatgtgatg caggaatggg ttcgagtgca atgggagctt ccagatttaa
    65521 aaatagaata aaaaacttag acttaaatat agaaattaca aattcatctg ttgataatct
    65581 tccagatgat acacaaatag tagtaaccca caatacatta gttgaaagag ttgctaagaa
    65641 taattcaagt gttgagatag tttcaataaa caatttttta aatgacccaa atttagatac
    65701 attgtttaaa agattagaat ctaaataaaa ataaaaagta ccactaatta ggagtggata
    65761 atttgaaaaa aaagaagatt acatctaggc aaaaaaagat aatactaatg atagtagaaa
    65821 attcaaagaa aaacattcca ataactattt ctgagattgc agggacttta gagttaagtt
    65881 caagaactgt acttagagat atgtctggaa ttgaaaaatg gtttgatgaa aatgatttta
    65941 actttgtaaa aaaaccagga gtgggattga ttttagagga aaatatagaa aatcaaaact
    66001 ttataattga gttgttagaa gaagaaaaaa tagaaaaaga atacagcaag gaagaaagaa
    66061 atttaattat attatcaaag ctactagttt ctaacgagcc agtaaaatcc tattattttg
    66121 caaaaatatt aaaggtatct gaaggagtac tgaataatga ttttgcctta gcaagtaaat
    66181 ggttggaaag atttgatatt gagcttgtta gaaaaccagg gcttggtgtc tacttaaaag
    66241 gtcaagaaaa aaactttaga gaggcatatg taaatcttat atacgattca ttcaatgaaa
    66301 aagaaatact agatatggtc agaaatataa gtgaaaatat acaaacagat aaagcaatag
    66361 aaattttaag tgaaaataga cttttaaatt taatggacag gtgcataata agaaaagttg
    66421 aagctacatt aacaaagaag ctttcagatt tagatgtaaa tttagctgat agtgcatata
    66481 tagggcttgt agttcatatt tcattagcct tacagaggat aaaaaatggt gaaaatataa
    66541 ctatggataa agagtttcta aaagaattat ctataacaga agagtttaaa ttagctaaag
    66601 aaatcgtaaa aggtatggaa acagatttta acatggatat accagtagat gaggttggat
    66661 atataaccat gcatataaga ggtgcaaagc aaaggtcatc ttcaaaccat aaggctttaa
    66721 acttagatga tatagaaata atggaaatta caaataagat gatagatttg gcggaagatg
    66781 aatttaaaat aagtttaaaa aatgacgaga ggttatttaa agacctagca aatcacttag
    66841 ggccttctat aaataggttg aatatgggat tagaaataag aaatcctctt ttagatgaaa
    66901 taaaaagcaa gtattcatat gcctatgatg gagttgaaaa gatttctaga attataaaag
    66961 ataaactaaa tataaattca atacctgaat cagaaatagg atatattgca atgcactttg
    67021 catcagccat agaaaaaaat cttatgatga atactaatat aaatattgtt gtggcatgtc
    67081 ccactggaat aggtacttca agattcttat caactaagat tgaaaataaa tttcctaatt
    67141 taaatatact tgaaaccata tcagctataa acatagatga agagtattta aaggaaaaag
    67201 atgttgattt aatagtgtct acagttgagt taaatacaag tttaaattat atatgtgtag
    67261 gtccatttat gagtttagat gatgaacaga taatcaagga aaaaataaaa tctatagctc
    67321 aaaataaatt aatcaattta aatgcgaaaa atgatactaa gagtaagaat agagtgtatg
    67381 aacagataac agaaagtatg aatataggaa aagatattct tcaattttta gaggaaatta
    67441 gatttgaaaa atttgaaagt aaaaatttaa gtgagcttat tgaagactca tcaagaatat
    67501 ttgcaaaatc tagtgaagat ataatctcta taaaagaatc gttaaaagaa agattaaaaa
    67561 tctcaattcc atatatagaa gaatcaaaaa ttctattgtt acattgtatg agtgaaagaa
    67621 tagatattat gaagttatca ataataaaac tagagaatag aatcgtgcta gattcaaatg
    67681 aagaaatcga caatgtagtt tttatgttac ttcctaaaaa ttcaccaagt tatcaaagac
    67741 aaataatgag tgaaataagt ggttcattaa tagacaatat aatttttact aataagataa
    67801 ataaattctc tatagaagag atggcattag aggtaaaaga tatagttttt aatttttata
    67861 caaacagatt aaaagcattt atagataaat aaaattaata ttaaaaagga aggttgatac
    67921 tatgagtaaa gtattgaatg agaataatat atttttaggg ttagatagtg tttcaaagga
    67981 agaagctata actttagcag gaagaaaatt agttgaaaat ggatatgtaa aagaagaata
    68041 tataccagca atgttagaaa gagaaaaagt aatgactaca tatatgggaa tgggagttgc
    68101 tattccacat ggtgtaaatg aagcaaaaaa agaaatatta tcttctggaa tagttatatt
    68161 acaattccct aatggtatag attttgatgg agaaaaagca tatttattaa taggaatagc
    68221 tggtgttgga gatgaacatt tagaaatact atctaatata gcagtagttt tagatgatga
    68281 cttaacagaa agactaaaaa attcaaatga caaacaagct tttatggaag cttttgccaa
    68341 ctaatcttag gagggattta aaatgaaaaa ggcaattcag tttggagcag gaaatattgg
    68401 aagaggtttt attggaggct tgttagttaa gtcgggttat tatgtagtat ttgctgatgt
    68461 aaatgaggat atattaaact caataaacaa agataaaaag tatactatac acataagaga
    68521 tgtagaatgt atagatgaag taattgataa tataagtgcg gtttcatcta taaaagaaga
    68581 aataatagat gagattgtac aggctgaaat aataactaca gcagttggac ctttagtttt
    68641 gactaaaata gcctctacaa ttgcaaaagg tataaaggct agaaaagaaa agggattaac
    68701 aagtaatcta aatataatag catgtgaaaa tgcaatatac gcaagttctt ctttaaaaga
    68761 agaggtactt aagtatttaa ataaggaaga agtagaatat ttagagatgt atgttggttt
    68821 tccaaactgt tcagttgata gaatagttcc tcctggtaaa aacgaaaatc ctcttgatgt
    68881 aacagttgaa aatttttatg agtggaatgt tgaaaaacaa ggatttaaag gggaaatacc
    68941 aactatagtt ggaatgaatt tagctgataa tcttatggct tatatagaac gtaaattgtt
    69001 tacactgaat acaggtcatg ctataacagc ttatatagga tatttaaaag gatataagac
    69061 tatagaagag agtataaaag ataaatttat ctgtgatata gtcaaaagtg caatggtaga
    69121 aagtggagaa ggattgatta aaaaatacaa ttttgactca gaagtgcact ataaatatat
    69181 tgataaaatt ttaaatagat ttaaaaatcc atatcttaat gatgatgtat taagagtcgg
    69241 aagggaacca ttaagaaaac taagtgataa agatagattg attaaacctt taatgacagc
    69301 aaaatcatat ggattatcag ttgataattt gattcttgga ataggtgcag cgcttcatta
    69361 taataatagt gaagatactc aaagtgtaga attacaagag ttgataaagt ctattggggt
    69421 aaaaaaagcc gttgctaaaa tagctaatat aagcaatgac gaagaacttt taaataatat
    69481 cgaaaaaagt tatatattta tgaaaaattt ataaatttac ttgaaaaaaa gtagttctga
    69541 taaagtaact ataatatatt attctacaca gtttgaatta tttgttgaat aatagagaat
    69601 tataatatat aattaaaagg aataaattaa tatatttacc tgtatatgtt tgataatatg
    69661 gttcaaatgt ttctactaag ctaccattaa tagcttgact acaggagtga agaagatata
    69721 gtttatactt attttaaatt atatattaag ttaattactt tgaattttaa gctcctgtct
    69781 atgatataga caggagcttt tttagtattt taatataaaa tacttacaag aatagatagc
    69841 aaaattagaa caaatataat ttttttatta atataatttt agaaagggct aggtggaagt
    69901 tcaatgaagg ctttacaaga aaagatattg agagaaggca gtgtttcagg aaatgatata
    69961 ctaaaagttg atagtttttt aaaccatcaa attgatgtag cttttttaaa tgaaatagga
    70021 agagaattta aagagagatt taaaggagaa aaggtggata agatatttac aatagaggct
    70081 tcaggaatag ctatagcatc aattgtttca cagtattttg ataatgcacc tgtagtattt
    70141 gcaaaaaaat cagaatctaa aaatttggat aaagatgtat atgaaactaa tgtatattca
    70201 tttactaagg caagagagta ttcagttaaa gtttctaaaa agtacataaa caaaggcgaa
    70261 aatatattga tagtggatga ttttttggca aatggaagag ctgctcttgg acttaaagat
    70321 ttaattgagc aagcagaagc taacttagtt ggagtaggaa ttgtcattga aaaaggattt
    70381 caagctggag gagcactttt aaaggctaat gatgtaagat tagagtcttt ggcagtagtt
    70441 gaatctatag ataatggaac tgtaaaattt aggtaattta tgatattata tacttgtgtt
    70501 tagcacatat tttaactatg taattatgga ggatttttta tgagattttt tatagacaca
    70561 gccaatattg aagaaataaa agaagcaaat gatttaggtg taatctgtgg tgtaactact
    70621 aatccgtctc taatagctaa agaaggtaga gattttatag aggtagttaa agaaataagt
    70681 gaaatagtag atggaccaat aagtgcagaa gtaataagtt tagaacataa aggtatgata
    70741 gaggaagcag aaaaattatc taagatacat aaaaatatag ttataaagat acctatgaca
    70801 gcagaaggtc taaaagcggt gaaagtacta tcaagtaaag gtataaagac taatgtaacg
    70861 cttatattct ctgctggaca agctctttta gctgctagag ctggagctac atatgtaagt
    70921 ccttttgttg gtagattgga tgatatatca caaaatggtc ttgatttaat tgaagaaatc
    70981 gttgatatat ttagtgtaaa tagtattgag gctcaaataa tagttgctag tgttagaaat
    71041 ccaatacatg ttttacaagc tgctagaatg ggagcagata tagcaacagt tcctcttaaa
    71101 gttataaacc aaatgattaa gcatcctttg acagacaaag gaatagatag ctttatgaag
    71161 gattgggaag gtgcttcttt aaaattataa ttataaacta cgctttataa gtatattaaa
    71221 gaggttatta tggaaattct aagtaataag gctaggctat tttgcctagt cttattttgg
    71281 tgtataatat attgaaacat attattgaaa tagattaatt ttttaagtga ggaggcgaaa
    71341 aatggataaa atattaagag agatacaaag agaagataaa aaaaatccat atactgacca
    71401 agaacttgct gaaatgttaa atgtagctag gtctgaagtg atatcagtta ggaaaaaaaa
    71461 taatatttta gattcgagag aaagaagaaa aaaaatatta ataaaagata tatcaaaaat
    71521 tgtaagtgaa aatcctcaaa tgtctgaaag aaaaataact gaaatattaa tagaaaatgg
    71581 atataatata tcgagaagtg cagtttcaaa attattaaaa gaggaaaatt taaatcagtc
    71641 aaagattggg attaaggata aagacccagc atcatcagga aagtatgtga aggtgagtaa
    71701 agttgtagaa gaagatggat ttgaagaatt gataggtata aagggaagtt tgaaagaaaa
    71761 ggtaaatcta gctaagtcag caataatgta tcctcctaat ggccttcata ctataatata
    71821 tggagaaaca ggagtaggta aaagtgaatt agctacatgt atgtataaat atgctataaa
    71881 aaacaacatt aaagaagaga acagcccatt tatagtgttt aactgtgcag actatgcaga
    71941 aaatcctaat ctattgatag ctcaactctt tggggtagta aaaggtgcat atacaggagc
    72001 agatgcaaat agagaaggtc ttgtagaaca agctaataat ggaatattgt ttttagatga
    72061 aattcataga ttgcctgctg ctgggcaaga aatcttattt tcattaatag atagaggaga
    72121 atttagaagg ttaggagaaa gtagttctaa tagaaaggca aatgttctca taataagtgc
    72181 tacaacagaa aatccagatt ctaatttact tcaaacattt agaagacgta taccaatggt
    72241 aataaattta cctaatatga gtgaaagacc aaaatctgaa agatatgaaa taataataaa
    72301 gttttttgaa agagaagcaa agcgagtaaa caagaatttt ataataacta aagaagttat
    72361 gtgtgcactt atgaattata agtgtactgg aaatataggt cagttaaaga gtgatataca
    72421 agtaacttgt gctagagctt ttagtaaatc gatattttct agcgataagg taattataga
    72481 tttagatagt ttaagggatt atataaaaag tggatattat gattgtaatt gtaaaaatga
    72541 aaagtattct gagttttcag ttgaggatat atatatagat attagtgaat tggtgagtgg
    72601 aaaaaataga attttatctg ataatgagat aagcgagata tataattatg cagaaaaaga
    72661 gcttaaggtt ttggaaagta agtgcttttc agaagaagag ttaaaaaatg catttataga
    72721 aaagttagat aagaagttta atgctattaa aaacaataaa aatttatctg atagaagaag
    72781 tcgaatagac tggggaggac aattaaaaga gtctacactg gagataatgg ataaggtaat
    72841 tgtatttatt aaggagcagt ttaagcatgt aaatcaagga ctgtacttgg ctctagcaat
    72901 tcatattgag catgctatag gtaggataaa agatggaaaa actataataa atccgagttt
    72961 agataaaata aaagcatcaa tgccaatgga atatgagttg tcaagatata taatgggtat
    73021 agtagaagat ttgacacaag taacatttcc agaagatgag cttggatatt tggcttatta
    73081 tataaataaa ttttgttata atgaggaaag tataaaagat aaagttaaag tagtaatagt
    73141 tacgcatggt aaagttggaa ttgaaatgtc taaagttgta aatcatattt taggtataga
    73201 atgtacacta ggtatagaaa tagcacttac agattcacca tcagagggga tagagcatgt
    73261 attagaagag cttcaaaaga tagaagctag aaaaggtatt ctagttctaa ttgatatggg
    73321 ttctttggta attcttggtg atgaggttga aaaaaggctt ggaattagat gtaaaactgt
    73381 aaatagagta gatacattat tggcaatgga agcaggaaaa cttgcaacca ttgaagggaa
    73441 aagtttagat ggtataatag ctgatttaaa gaaaaataag aattatgcta tgataaatac
    73501 aaataaattt agttacagaa aaaacgagta tggaaagaaa aatgtaatca ttactttatg
    73561 tttgagtggt gtaggtacag ctttaaattt aaaagagcat atagaaaaac aaattaagga
    73621 atatgacact ttaattgaag taaagccagt tgctttttta aataataatt tagaagaaga
    73681 gttaaatgat attgaatctg aatataatat tattgctatc tgtggaacta ttgatataga
    73741 ttataaaaac gtgcctttta tttcttataa tgaggtactt ggtaaaaatg gtattaataa
    73801 agtattagag catttaaata gtaaacaacc agctttaaat attgaaaacc agttgaataa
    73861 tttaatacat gaagatttga ttttatacaa ttttgaagga atttcaaagg agtatataat
    73921 tgatactctt gtttcaaaac ttgaagaagg tggatatgtt gactcaaagt atatattaag
    73981 tgtatataaa agagaagcaa tgggaagtgt tgtaatggcc tctaaggtag ccgtgccaca
    74041 tggacttcca gaaaacgtta taaagcctgc aatagcaatc gcgaggttga ataaacctat
    74101 agtatgggac aataaattta tggtggattt ggtggtacta ctggcactta aagaaaataa
    74161 taagaaagaa atacgaagct tattttcaaa gattaatgac cagcatactt tagaagtttt
    74221 attaaatact gaagataaaa atgaaataaa agaactttta agctaattat tagtaccgag
    74281 aagaaagaca aaaaaatttg ctttagtata aaatttaaaa ctactcaatt gttaagtagt
    74341 taattactct atataaggct agttctatga aatttattta tatgatttta tagaattagc
    74401 ttttttcttg gtaaataaaa tatataaatt tatttatgta aaaagtaaat tttattggac
    74461 aattctatga gaatttttcc tatatttctt ataaaatata gaatatataa aaatatataa
    74521 aaataaatta aattcataat aaataatttt ataaaatagt tgttaaacat aaaaaaccat
    74581 ttgtaaaaaa caaaaaaatc atttctctaa caaaaaaaac cacaaaaaat ataaaaaagt
    74641 atggctagtt aagtgattaa caagtaaaaa ttaaaataaa aatcaaaaaa aaatttatca
    74701 atgaaagtca gctaaaatcc tggaagagag cattattttt gggaaaacat tttcttttgt
    74761 ttcacaaaaa aagccacttt ttggcacaca acatgcttta tataaagtca agaaaaacta
    74821 aggtataaga caaaggcaat taggaggtgt aaatatggag tttataaatt ttgtaagtga
    74881 taaagttata gaccttaaaa tggattgtaa aacgaaagaa gatttcttta aagaaataca
    74941 taataaagtt tttgatttag gctttgtaaa agaagaattt ggagaaaaaa tattagcaag
    75001 agaaaatgta tttccaacag gtttaaattt aggtgattat ggagtagcaa taccacatac
    75061 agatgcagaa tatattaaag agcaatttat atcagtctgt acttttaatg aaccagtagt
    75121 atttagttct atggaagacc aagaagaaaa agtacctgta aatttggctt tcgtattagg
    75181 acttaatcaa ccacacagtc aattatctgt attaacagaa ttaatgggaa ttatgcaaaa
    75241 taaagagtta gttgataagt tgatgagttc tactgataaa gaagaagttt taaagacact
    75301 aaagtcttta taaaaataaa aaagtactaa aaataaaaaa tataaaaata aaaattatta
    75361 ggaggaaata aaaatgaaaa aaatattagt agcatgtgga gcaggaatag caacatcaac
    75421 agtagtttgt gacaaggtag agagattagt taaggaaaat aatatacaag cagaagttat
    75481 acaatgcaaa atagctgaat gtgcaacaaa gcaagaagga gcagatttaa tagtatcaac
    75541 aactatacta ccaacaactt ataatatacc agcaataaaa gcaacagcat atataactgg
    75601 agtaaataca gtagcattag ataaaaaaat attagatgct ttaaaataat cctatcatag
    75661 atacattgaa ataatatttt ataaaacaga aaaaggagga tttataaatg gataaattat
    75721 tagcagtagt acaatacatt ttaaatatgg gaccgacagt aatactacca ataacaattg
    75781 tagtactagg aatgatattt agaattaagt ttacaaaagc tttaaagtca ggtcttacaa
    75841 ttggtatagg atttgtgggt ataaacttag ttgtaaacct attaacatca acactagggc
    75901 cagcggctca aggaatggtt gaaagattcg gacttaattt aacagtaata gatgttggtt
    75961 ggccaacaac agcatcagca acatgggctt caccagttgc accaatatta ataccagttt
    76021 gtttattagt aaacttacta ttattatact tcaataaaac aaagatatta aacgttgata
    76081 tatggaatta ttggcacttt atagtagcag gtgcagttgg atatatagta acaggaagtt
    76141 atgtttgggc tatattctgt gcaatactaa tggagttatt agtactgttt attgcagaaa
    76201 agacagcaaa aaatgttcag gagttttatg atttagaagg tatagcatta ccaactggtt
    76261 caacagcttc atttgctcca cttggatatt tagtaggtaa atttgttgaa aaaataccag
    76321 gaataaataa aatacaagca gacccagact ctatacaaaa aagatttggt atatttggag
    76381 aaccaatgat gatggggatt atactaggta taatacttgg ggcacttgcg ggatatgatg
    76441 tagcaggaat attcaatgta ggtatatcaa tgggtgcagt aatgttactt atgcctagaa
    76501 tggttagaat attaatggaa ggtttaattc caatttcaga atcaataaga gatttcttac
    76561 aagcaaaata tggagacaga gaactttata taggtctgga tgcagcagta gcaactggac
    76621 atccagcagt tatatcaaca gctcttatac ttgttcctat aactttgttc ttagcagtta
    76681 tactaccagg aaacaaagtt ttaccatttg gagacttagc gacaatacca ttttatatgg
    76741 catttatagt gtgctttaga aaaggtaata tagttcaatc agttataaca ggaacaatag
    76801 taatagctat atcactttat atggctacaa actttgcaga tgttcataca caattattac
    76861 aacaagcaaa tatgatgcca gaaggaacaa caatggttac aagtatagat acaggtggaa
    76921 acttgctaaa atggggaata ttgaaattat ctcaattagt ttcttcattt ggaatattct
    76981 aatatgtagt taatagagat tactcttttt tagtaaagta tgcgaaaatt taacatttag
    77041 cagctactaa aaaagagtaa tattttttat aaatttttaa aaatacaaaa tacaagagga
    77101 ggagatttat cgtgaaagca gcagtattac atggcacaaa tgatatgaga tttgaagata
    77161 tagaaataaa accatgtgaa agtgatgaag taaaaataaa agttatggca gcaggaatat
    77221 gtgggtcaga tcctccaaga gtattaaaac attggaaata tccagttcca gctataccag
    77281 gacatgagtt ttctggagta attgctgaag ttggtaagga tgtaaaaaat gtaaaagttg
    77341 gagatagagt agttgcaatt ccttttatac cttgtaatga atgtgaatat tgtaaaagag
    77401 gattattttc attgtgtgat gaccatggaa tgttaggagc taaaagtttt ggagcttttg
    77461 cagagtatgt aaatataaaa gctacaaatg tacttctaat aggagatatg gactttgaag
    77521 atgctgcaat gatagagcca ctagcagttg ctatgcatgg agtacttaat ataggtgttc
    77581 aagttggaga cactgtagcc gtaatgggta gtggaacaat ggggcagttg gtaatacaag
    77641 gacttaaaat agcaggggca ggaacaatta tagcagttga tatatctgat aataaattaa
    77701 gagaatcaaa ggaattaggg gctgatataa taattaatgc taaagatatt aacccagtag
    77761 aaaaaataaa agaacttact ggtggaaaag gtgttgacat agctcttgaa tgtgcaggtt
    77821 caaaaataac tcaagaacaa tgtttactta taactaaaaa gaaaagtaag ataggatttt
    77881 tagggatagc atattcagat ataactttat cagaagaagc atttgaaaat atatttagaa
    77941 aagaactaga attaaaaggt ttttggaact cttattctgc accatttcca ggacaagaat
    78001 ggactaaggg aatcaatcta gttaatgaag gaaagataaa attaaaagaa atggtatctc
    78061 atagattctc acttgaagat acttacaaag catttgaaat gataagagat agaaaagaag
    78121 aatttaacaa aatattaatt ttaccacaag gggttgaaaa ataatgaaag cagtagttaa
    78181 aactaaacca ggctatgata atgtagaagt tttagaagta gaagaaccaa aagctacagg
    78241 agacaaggtt aaaataaaag tagaatatag tggtatatgt ggttcagata tacattcatt
    78301 taaaggtgaa tatgcaaata taaaagcccc agtaacatta ggtcatgaat tttctggaat
    78361 tgttgtagaa gtaggagaag atgttaaaaa tataaaagta ggagatagag ttacatcaga
    78421 gactactttt gcaacttgtg agaaatgtat atattgtgaa actaaagatt ataacttatg
    78481 cccaactaga aaaggtattg gtactcaagt aaatggaagt tttgctgaat atgtattatc
    78541 aagagaagaa agcatacatg tacttcctga aaatgtatct ttattatcag cagcccttac
    78601 agagccacta gcttgttgtg ttcatgcagc tcttgaaaag actactatag aaagttctga
    78661 tacagtttta ataataggac caggaccaat tggtttatta ttagctcaag ttgttaaatc
    78721 tcaaggtgct acagttataa tgtctggtgt tacaaaagat aaggaaagat tagaaatagc
    78781 taaaaatctt ggagtagata gaactgtaaa tgtaatggaa gaaagtttgg cagatgtagt
    78841 gaatgaaatg actgatggaa atggagtaaa caaaggattt gattgttctg ggtttatgcc
    78901 agcagttaac gaagccttaa gactgcttag aaaaaaaggt actttcgtac aagttggaat
    78961 ctttgctaaa aaattaaatg aaatggacca agaagcaata atccaaagag agttacaata
    79021 tataggaagt agatctcaaa agccaagttc ttggattaca gcattagatt taatggcaag
    79081 tgggaaagta aatacagaag ctttagttac tagaactgtt ggtttagacg aatttaaaga
    79141 aggtattaca gctttaatga acggggaaga aataaaagta gcagtaaaat cttaaaaaaa
    79201 catttgtatt attttaaaaa aaattgtaaa atctactgta ggataaaaaa atgtaaggtc
    79261 ttaaaaaata acaggaggaa gaaagtatga gcactcttag agatcattct aataatatta
    79321 gaaaaaacat aataaaaatg gttgcagaag ctaaaagcgg acatccaggt ggttcattat
    79381 caatagctga tatgttgaca gtattatatt ttgataagat gaacgtatgt gcagaaaatc
    79441 caaaaatggc tgatagagat agatttgttc tatcaaaagg tcatgcagca ccagctttat
    79501 atgctacatt agcagaaaaa ggatttttcc cagaagaaga attaataaca ctaagaaaat
    79561 ttggttctaa gttacaaggt cacccagaca tgaaaaaagt agcaggaatc gatatgtcta
    79621 ctggttctct tggtcaaggg ctatctgcag caaatggtat ggcacttgca ggaaaattag
    79681 ataacaaaga ctatacagta tatactatat taggtgatgg agaaatccaa gaaggtcaaa
    79741 tatgggaagc tgcaatgaca gcatcacatt acaaattaga taatttaatt gcatttgttg
    79801 acttaaatgg attacaaata gatggttcta atgaagaagt aatgaatgta aatccagtag
    79861 atgacaaatt caaatctttt ggatggaatg taatagtaat aaatggacat tcttttgaag
    79921 aaataggaaa tgcagttgat gaagctaaaa aagttacagg aaaaccaact gtaataatag
    79981 ctaaaacagt aaaaggtaaa ggtgtttcat ttatggaaaa taatgctgca tggcatggaa
    80041 cagctccaaa tgcagaacaa gcagagcaag cattgaaaga tttagaagga ggtctatagg
    80101 aatgggaata gcaactagag aagcttacgg acaagtgtta aaagaacttg cagaaaataa
    80161 agatatagta gtattagatg cagatttagg aaaagctaca aaaagtatat catttaaaga
    80221 agttgcccca gatagatttt ttgacatggg gatagcagaa ggtgacatga ttggtacagc
    80281 agcaggtcta gctacttgtg gaaaaatacc ttttgcgagt acttttgcaa tatttgcagc
    80341 aggaagaggc tatgagcaaa taagaaactc tgtagcatat ccaaatttaa atgtaaaaat
    80401 agcagctact catgcaggtg taacagtagg tgaagatggt ggtagccatc aagctataga
    80461 ggatatatct ctaatgagag gtataccaaa tatggttgta ttaaatccag cagatgcttt
    80521 agaagcaaga caagctattc ttgcatctat tgattataat ggacctgttt atataagatt
    80581 aggtagagct gcaactcctg atgtaaacag tgaaaactat aaatttgaaa taggaaaagg
    80641 aactgtttta agagaaggtt ctgacataac agtaatagct acaggaataa tggtagcaaa
    80701 agccttagaa gcagcagaag aacttgctaa agaaggtata aatgtagaag ttgttaatat
    80761 atctacaata aaaccattag atgaagcatt aataaaagaa actgctaaga aaactggaaa
    80821 agtagttaca gcagaggagc acagtataat aggtggttta ggttcagctg tatgtgaagc
    80881 tttagcagaa actaaagatg tagtagttag aagaattggt gttaaagatg tatttggtca
    80941 atcaggtaca ccagctgatt tattaaaaca ctatggttta actacagaag atatagtaaa
    81001 aaatataaaa gagttgttat agatataaat atatctaaat aataaattga tttgacataa
    81061 gtcaattaaa gctgtcttaa aaatagaaag aaatttctac aatgggacag ctttattttt
    81121 acaatacttt atttttatga taattataaa atagtctgaa agtaatcaaa aaaattataa
    81181 aaagaggtgc tatttaatga aaatatctat tggatgtgac catggtggtt atgaattaaa
    81241 ggaatatata aaggaaaatt taataaataa aggtatagaa gttgaagatg tgggtacaaa
    81301 ttcaaaagaa agtgtagatt ttccaatata tgcaaaaaag gtaagtcaaa atgttcaaag
    81361 taaaaaatct gatttaggca tactttgttg tggaacagga ataggtatgt ctattgcagc
    81421 aaataagttt aaaggaatca gagcagctgt tgtttctgac tgtttttcag ctaaggcaac
    81481 tagagaacac aataatacaa atgtactttg tttaggagaa agagttattg ggaaaggatt
    81541 agcaatgaga attgttgaag aatggttaaa ttcaagttat aatggagaaa gacatgcaag
    81601 aagattacaa atgattgatg atatagaaaa agaaaattta taaatatata atttataaca
    81661 agggggagcg ttatgtctat tatttgtgct tcaataatgt gtgcagacca aatgaagtta
    81721 aaagaggaat tagaagctct tgaagaagca ggtgtaaaat tacttcattg tgatgttatg
    81781 gatggaatat ttgttaaaaa cttggctatg ggaccagagt tattaaaatc aataagtgaa
    81841 aatacaacaa tacctttaga catacactta gccacagaaa ctccagataa atatattgat
    81901 atgatgtctt atataaagcc aaaatatatt tcttttcatg tagaatcaag tacaaatgta
    81961 aaagctgata tacaaaagtt aagaaattat ggtatagggc cagtgttagc aataagccct
    82021 caaacaagtg tggataaaat agaagaatat ataagtttag ttgagggtat cttagtaatg
    82081 acagtaaatc cagggtttgc aggtcaaaag tttaatcttt ctgtattgga taagttggat
    82141 aaacttacag agatactaaa agattatgat aatcctccat ttatagaggt tgatggaaat
    82201 ataaataagg atactattaa acttatgaat ggtaaaaaag tagatatata tgttgttggt
    82261 acttcagctt tatttaatga taagcctcca atttcatata aagataaaat agaagaacta
    82321 aaagaaagta taaagtaacc atgtaataaa attataatat gtttctgttt aatagtaaaa
    82381 atttaggtgg aaacaagaaa ttttataata tttaataaaa attttggttg agtaaggaga
    82441 attttttatg ggagacctat ataaactaca aaatggtact gatattagag gaatagcgta
    82501 tgaaaatgat tctaaagaag ttaacctaac tgtagaagaa gtaaaaaaaa tagctaaagc
    82561 gtttcatatt tggttaaaag aaaagactaa gaaagataaa gtaactgttg ccataggaac
    82621 tgattctagg ataacaggaa gccaatttag aaatactgtt attgaaactt taactaatga
    82681 tgattgtaat gtaattgatt gtgaaattgc cacaactcca gctatgttta tgacaactat
    82741 tatggatgga tataattctg atggggcgat tatgattaca gcaagtcact taccttatta
    82801 ctataatggt ttaaagtttt tcacagaaag tggaggtttg gaaaaaactg atataaaaga
    82861 gatgttggat atagctgtta aaaatgatag tgtagactat gaggaagtaa ataaaaaagg
    82921 tgaagttata gtaaaaaatt taatagaaga ttattctaat ttattgatag ataaaattag
    82981 aaaaggtgta aattcaagta aaaattatga aaagcctttt tctgggctta agatattggt
    83041 tgatgcagga aatggggctg gtggattctt tgctgaaaaa gttttacaca tgctgggagc
    83101 agatacgaca ggtagtcagt ttttgaaccc agatggtatg ttcccaaatc atatacctaa
    83161 tcccgaaaac aaagaagcaa tggaaagcat atgtaaagct gtgttggata ataagagcga
    83221 cctaggaata atctttgata cagatgtaga cagagctgct attgtaggta aaaatggcaa
    83281 accaataaat aaaaatgctc ttatagctgt tatatcatca atagtattag aagaacatcc
    83341 aaaaacagct atagtaacag attcgattac ttctgaagga cttgctaaat ttataaatga
    83401 attacaagga agacatcata gatttaaaag aggatataaa aatgtaataa atgaagctat
    83461 aagattgaat agtgaaggtg aagagtgcca tttagctata gaaacatctg gacatgctgc
    83521 tttaaaagaa aattatttct tagatgatgg ggcatattta atagctaaaa ttttaataaa
    83581 agtagcaaag ctatccttgg aaggaaagac tatagaagaa ttgatagaaa accttgaaga
    83641 agctcaagaa gagaaagaag ttagaatagg cattaataaa gaagatttta gaccatatgc
    83701 agaggatata ttaaaagatt tagattctca tgttaagagt attgatggat ggtctgtagc
    83761 accaaataat tttgaaggca taagagttaa ttgtgatgaa tcaaatggag atggatggtt
    83821 tttacttaga atatcactac atgaaccatt attagcttta aatattgaat caaataaaat
    83881 tggtggagca gaacaaattt attctaagtt aaaacttttc ttagaaaaat atgatttaaa
    83941 aggtctttag ggtaaataga aagaatatat ttatattgaa gaataaatgt aaatttgtac
    84001 ctaagattac aaatattaca aaattgtaat cttaggtaac agagatgtaa ctgattatgg
    84061 aaacactatg tgatattata gatacagaga gatgaaatat gtgatgaatt atagagaaat
    84121 ataatttaaa atgtattaat atcacaccaa aaaggtataa tcaaaaaata tgtaaatata
    84181 aaccccaaca tttagaaaaa gacctctaag gaggtttttt tcttgtttaa ataacttaaa
    84241 atatattttt atattaatat atcaattaac tcttctaaaa gtaagcatta ccttaaataa
    84301 atcagcatct ataattattt ccatgtgtgc attttctaat tcaattatat tttgagcaat
    84361 tgataaacca agaccagagc catctgtttt tctagatata tcaccccttc taaatctttc
    84421 tattaactct tctggtttta gatttagttt atcatttgaa atatttttaa acgttaatat
    84481 tatattttct tcctttataa acatatctat atagacccta gtgttaggca tagagtattt
    84541 tagtatattg caaattagat tctcaaaaac tctccaagtt tttttaccat ctatcatggt
    84601 aaaaacagca tattcaggtg tttctattat aaaatctaaa ctgctatttt gaattttgtc
    84661 ttcaaactct acaatacttt gaattaaaag ttctcttata tcggtttttg ttatattaaa
    84721 ttctacatct ccactactta gcttagatgc ttcaaatatg tcatctatta ataattttaa
    84781 tctttgtgat tttttatcta aaatatttat atagtcattt atagtctctc tgtcaaagtc
    84841 attatttttt aacatgtcaa catagcttaa tatagatgta agtggagttt ttaagtcatg
    84901 agatacgttt gtgataagct ctgccttcat cctttcattt tttatattag catctacagc
    84961 agtttcaaga ccacctgtta tattatttat acttttggct aaagtagata tttcatcatc
    85021 tcctataact tctaatttat actttaaatt gccattttct atatttttta tattttttga
    85081 tatgttattt atgtaattaa acttaacaga taaaaagttg tatatataaa aatgaaaaac
    85141 tgtgtttaca agtgtaaata aaattactat agctattgca tcagcataat atatatacat
    85201 aaagaatatc aaaacaagat attggataat agcttgtaca actatagata ttaaaaatac
    85261 tatagctaat tttttattta tagttttttt attatacata ctaagtaagt ttgaaaagaa
    85321 tacatatgtt atagacatat cttttagatt atagttatta tatttaatgt tttcatatat
    85381 tatatagact atagatataa ttataaaatt gtagattatt aaattagtgt tgtaaaacat
    85441 tttattactt gtaaatgcat gaaaccttac ggttaatagt accaaagtta atataagtgt
    85501 aagttctatt tttaccttag aaaaaaggct tatgacattc tctaagaatt tgactttagt
    85561 ctgtttattt tttttataca atgtaaaaca tagtatagtc aataaaaaac ttgataatat
    85621 aatacctatg cagacaaact ctaattctgc ttttgacaaa tgtacaggag taccgaaaaa
    85681 ataaaaataa gggagagcaa actctttata ataacaatta atattataag aaaagttatt
    85741 attcaaatca taaactgctt caaataatat agaaactaat agaaacagta ataataataa
    85801 aataaatttt gctttagaat cattaataat taagtttttc aattttgtaa ccaatgcccc
    85861 acaccacctt taaatatttt ggttcttttg gattaatttc aatcttttct ctaattcttc
    85921 taatatgaac agcaatagtt ctctcacaac tataagcatc ctcattccag acattttcat
    85981 aaatctcatg agaagagaaa attttacctt ttcgtgacat aagaagtgta agtattttat
    86041 attcaagtgg tgtcatttta atttcctcac catctaaaga aactattttt gtatctgtat
    86101 ttagctctag gccaccactt tttagaatat aattagtatc atttgagtta tttgtattac
    86161 taaaatcacc taaatttata taccttctaa gttgagattt tactcgagca gtaagttcta
    86221 gtggattaaa tggtttagtt atatagtcat cagcacccat attaagacct ataattttgt
    86281 ccatatcttc tgattttgca gataagagaa ttattggtat attctttttt tctcttattt
    86341 taagtgtagt tttaagccca tctaaattgg gcatcattac atccattatt attaatttaa
    86401 tatcattttc gattagtatg tccaatgctt caagtccatc atatgccttt aaaacattaa
    86461 agttatcagg tctcaaatag aactctatag catcaactat ctctctatca tcatctacaa
    86521 ccaatatatt ttgattcaac ttattaaccc ccttgaaatt ttatttttaa ccaattttta
    86581 ttttatacca aaaagaggta ttagaaaaca gtaagcccgt tcattatgaa ataaaaacta
    86641 gtacttttaa tatattgtca atgcatatag taaatttaaa agtatagacg cccatattaa
    86701 tctgaaggta aaagtttatg aaaatatcta gggtaatcta tcacacttct tatgttattt
    86761 tggtttatta attttttagg tttaaacata tattaacaaa tataaataac aaatgagttt
    86821 cataattatt aagaatttat aacaaatatt tattttaatg tagtttaata taaacaggta
    86881 gtttaatgta ggtatgtata aagcatttaa taaggcttat aggttttaat gatgatatct
    86941 ttatatattt taagagatga tgaaattaga tatgggtaat agttgtatga gaaaaagtag
    87001 tatagcacaa aaagtgctat atcacaaaat ctcaaataat ttccttttta taacttaaat
    87061 taaaagaata aatatttctt ataaattagg tgtatgaagt atagcaggaa catctttatt
    87121 atttaataac ttatcaaatg atttatggtc agacttatag ccaatacctt ctctatattc
    87181 taattcatca acaattttgt attgttgaca ggcattttta accttttcat agtcttcagt
    87241 agaatgagct ttataaacta tcttattatt aaaagttatt ttatcagcaa atttaggttt
    87301 tacaaaatat ttagcatctt ttattttacc agcattatat aaattttgga taacagaacc
    87361 attttttaaa tgttgtaaat ggtcatctaa cttataagta tgtgctatat gagttacatt
    87421 tttaaatttt tcttcaaatg taagagcaat tttttccatg taattgaagt cagtattacc
    87481 atttgtattt gtttctggta ataatattat attttccctt attacgccaa ggctattaag
    87541 agaagctaaa aattctctat ttctatattc tgatttttgt atatttgtta ggttttcata
    87601 ttttttatat ttatcaaaga cggatatacc acatccagta gatactaaaa ccacaaatac
    87661 atgatttttt cctctttctt ttatagcatt aacaatagca ctcccagccc acaacacttc
    87721 atcatcttga tgctgaacat agaagacaac ataatcttta aattttttat gactataatt
    87781 cacatagcta ctaaaagcgg ttaaaatcaa acataaaact agaataatag atagaatttt
    87841 atatttattt atagtaaatt ttttattctt aaatgtcatt taatcatctc ctgaaaagtt
    87901 gtcttagtta tattatcaaa caaagtacta aaaattattt cttaaatgct gaaaaatata
    87961 gagtagatta atggaataaa atttttttat tagtttaaaa taaagaaaac atttatgtat
    88021 aagactaatc aaaatattaa tgattgatag gaattgagat ttaaagggat tgtacattta
    88081 ttcgggattc attttaatag aattttactt tagtacttag aataaaagta ataacttttt
    88141 aaatttaaag agtacacata tatatttgtg tactccttga tgatatgatt gcttatttac
    88201 tacaaaaaca gagtcttttt aaacctaaaa tatttgatgc accagctatc gtagttccat
    88261 aatagtaaac tggtttgtta agtgatagaa aatttataat tgagttatta cataatgtac
    88321 ttcctgtgca aatcactaaa tcagcccaag atattacatc ttcataatct cgtataccat
    88381 cttcaatctt aacattatat tgaatagtat ccacaaattc aggatttaaa tctaatactc
    88441 ttgtttcgaa aaagtcctta atattatcaa ttatggctgg ttgatatcct ataattgcta
    88501 cttttggatt accaaattcc atttttataa actcagggaa tttttttgca catacctctg
    88561 gctcgttatt tttacaatga atggttctat ccgtcttgcc taagtatttc ataactgcat
    88621 ttaatgatgc tataaaaaga cttctatcat gaggattgtc atgtaaatct aatgataata
    88681 tgtcttttaa agaaccttca aatgtagatg gagtagaagt aaatgcttgt cctttagctc
    88741 ctttaaagtc agcttcaagc attatttctt taccaactat aattgggaaa tctttacgct
    88801 tagtatttcc aattgcttct tttgaagata gagatttgga cacaatactt atcatatcca
    88861 tatttaaatt atatttatcg acttgtacta atagataatc tctcaaaata tcaaatatat
    88921 tcatagaaaa aagattctcc tttatttttt atttcttcat ttaaatcaaa aatatgattt
    88981 atttttccat tgttcattat tcctatctta tgagcaaaaa acattgcttc agaaatatca
    89041 tgagtaacat gaatcactgt tggtttgtat tttatgtaga catccttcaa aattttgctt
    89101 atatgttttt ttgtaatata atccaatgaa ctcataggtt catctaaaag taatatatca
    89161 ggttcagcta ttaaggcacg tgcaaaagca actcgttgct tttcgcctcc acttaaattt
    89221 ttaggatacc tattttttat atcttctatc tgcattaatt tagacaagtg gttagcctta
    89281 agaatctgtt catctatagg tatttttctc aatttaagtg gaaaccttat attatcttca
    89341 acattcatat ttggaaataa ttcaaaattt tgatatacaa atcctatatt tctattttct
    89401 ggaggtaagt ttgatattaa attttctttg tatgatacat ttcctttagc agatggatat
    89461 cttcctgcta atgtttctag aaatagagtt ttacctgacc cactagctcc taataaaaca
    89521 aagtattcat gattattaat atttaaacta ttttcttgta atttaaaatt aggtaaatca
    89581 agagataaat tttttatttt taacatatta attcttatca acctctctat taaaaaatat
    89641 ctcaaaaagc atcaagcatg taagtgagat aaatatcaaa attacagcta ttccgatagc
    89701 aatgtctata tcaccagtag acatatttaa atatatagat gtaggaataa tttcagtttt
    89761 catacgtgta gaacctgcta tcatagctac tgcaccaaat tcaccaagtg ctcttgacca
    89821 agtcattaca gttgcagata tgattccagt ttttagattt ggaagaatta taaatctaaa
    89881 tgcttcccaa ctattacatc caagggtacg tgcaacaaat atcatctttt cattactttc
    89941 atttagtgaa gtgtgaagta ttttaatagt aagtggaaga tttacaaata cttgtgctaa
    90001 aactatacct tgctttgtaa atataaaatc aagcttaaaa atcttataaa tggaatctcc
    90061 aatccccatt cttccaaaca aaagtaaaag agcaattcct gatactaagt gtggaagaga
    90121 catagggaga tttattatct gtataatcag ttttttaaat agtaatttag taatatgtaa
    90181 aaaatatgct actggaatag ctaataaaag gcatactata gtagatatta aagatgtttt
    90241 aatactaagt gttattgcat actgtacttc cactgatttt aagcatatag gaacataact
    90301 tataccttta atgattaaca taagaagtgg tgatacaata aacaaaaaga ctatagcaaa
    90361 aaatccagta agtagtgtag taaaaaattt atttttcaag tttaatcact acttaacagg
    90421 ttcaaaacca tattttttaa atatctgttt agcttcgtct gactctatat aatttataaa
    90481 tttattagct aaatcttttt tatcactata gtttacgatt cctgctgata tgagttggtc
    90541 tatattttta tcttgggcaa tttctataac ttctacatct tcattgccaa agaccgaatc
    90601 ttttgtggct attgtagcat cagctttact tgatgttaac tgtacaatca tttcatttac
    90661 agttgcagct gtagagacaa cattatcatt tatagatttt aaattatttt tttcaagtat
    90721 tttttgtgta gtcttaccta tagcattaga ctctttgtct cccaaaataa gtttaactcc
    90781 atctttattt aagtcttcca atttttgaat attagctgga tttcctttag gtacaactat
    90841 tgcaggtgta tgatgtgcaa ccgttttatg ttcacctaca agttcttttt caaaggcctt
    90901 tgaataaatt ggttcagaac caacaataaa tacgtctcct ttgtgacttg tctcaatttg
    90961 agctattagc tgtgcagagc ctgcatagct atattcaact ttgacattat tttctttctc
    91021 aaattttttt gctatttcat ccattggttt ctttaaacct gcccctgaat agacaaaaag
    91081 agtctctttt tcttttgaat catcagctgt tgtcacttta gtattagatt catcattagc
    91141 tttgttttct ttagaattac atgcagtaat acttaatgaa ataatcatag ctaaagctag
    91201 tactgaaagt tttttaaaca taagatattc ccccttagta aattagtgta aattcttttt
    91261 tagtatatca tactaagaaa acgatgtcta agtttttgtt atgttttata atgttttgtt
    91321 atgttttgtt atgtatagtt aagaaaaaat ctattcataa tgtcatttcc ataggtagtt
    91381 attttatttt taatttttat tagtacttta aagtatttta aatttaaaaa cttaaatcaa
    91441 attaacttat tgtagatttt ttatttttta actaatttta tatttattat atttcagtga
    91501 aaaaatagaa cattgaaaca tatagatatg ttttaattgt tttttattaa caaattacta
    91561 aaagtgttat atcagaattg aatacaaaag aaagagtatg tatttatgag atagttgaaa
    91621 attttggtgt gccacaacta aaattattat attactatat attctaatta aaagagtact
    91681 tgtaggttta agtacatact ttataaatat atttttgtca gatttatttt ataaaaagta
    91741 tttagactaa gtattatttt taagtatttt cttgttgaag ttattttttc cttttttaca
    91801 aaatgcgtaa ataaaaaaaa gactcttaaa agagtctttc cgaaaaatct atatattata
    91861 atatagttat attttctgct tgaggacctc tagcgccttt aactatatca aagcttactt
    91921 tttgaccttc ttctaatgat ttaaatcctg aagtttgtat agctgagaaa tgagcaaata
    91981 cgtcatctcc actttccatt gatataaatc caaatccttt ttcattatta aaccattt
//
LOCUS       DAEORM030000010        85662 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.010, whole genome shotgun sequence.
ACCESSION   DAEORM030000010 DAEORM030000000
VERSION     DAEORM030000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 85662)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 85662)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 85662)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..85662
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.010"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            252..1448
                     /locus_tag="KRH23_001008"
     CDS             252..1448
                     /locus_tag="KRH23_001008"
                     /EC_number="2.7.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_function: GO:0016774 - phosphotransferase activity,
                     carboxyl group as acceptor [Evidence IEA];
                     GO_process: GO:0006082 - organic acid metabolic process
                     [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetate/propionate family kinase"
                     /protein_id="HHS5224297.1"
                     /translation="MKILVLNCGSSSLKYQLIDMNNEEVLCIGLVERIGIEGSILKHE
                     KAGRDDKYVVEQPMKDHKDAIALVLEAVAHPEFGAVKEMKEIDAVGHRVVHAGEKFAT
                     SVVITPEVEEALKECIDLAPLHNPANIMGIDACKAILPDVPMVGVFDTAFHQTMPKSS
                     YLYGLPHELYTKYGVRRYGFHGTSHNYVSQRAAEILGKDIKDLKIVTCHLGNGASIAA
                     VDGGKCVDTSMGFTPLEGLIMGTRCGDIDPAILPFLMRKEGLDADGLDKLMNKESGVY
                     GMTGISSDFRDIEDAAKNGDERAQATLEAYVKKVQKYIGAYAAEMNGLDVVVFTAGVG
                     ENGKAIRADIASNMEFLGMKLDKEANDVRGKETVISTADSKVKMLLIPTNEELMIARD
                     TLRLVK"
     gene            1541..2065
                     /locus_tag="KRH23_001009"
     CDS             1541..2065
                     /locus_tag="KRH23_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YceD family protein"
                     /protein_id="HHS5224298.1"
                     /translation="MKVSIEKINRKETDKIDLNFCEKIDTISYCDEIYKLVSPVNLKG
                     KVSKTNKGLYLDIDVNFTIVDNCSRCLKEVEIPLEYSIQGFLVKEEDYDEDEFEEFDP
                     FIFDGEEIDLIDIIEQTLDFNVPHKVLCSENCKGLCQVCGANLNEEECSCSEITNDEE
                     YIDPRFAKLKDLFN"
     gene            2090..2266
                     /gene="rpmF"
                     /locus_tag="KRH23_001010"
     CDS             2090..2266
                     /gene="rpmF"
                     /locus_tag="KRH23_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HHS5224299.1"
                     /translation="MAVPKRKTSKSNTKMRRAANSKMEATGFVSCPQCHEPKLPHRVC
                     PDCGYYKGKEVVSK"
     gene            2473..3030
                     /gene="fapR"
                     /locus_tag="KRH23_001011"
     CDS             2473..3030
                     /gene="fapR"
                     /locus_tag="KRH23_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0045717 - negative regulation of fatty acid
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription factor FapR"
                     /protein_id="HHS5224300.1"
                     /translation="MKKKSKAQRQKELIDMLKTDPFYTDEELSSLFDVSIQTIRLDRM
                     SLNIPELRERVKSIAETQSSKVKTLGVKEITGEIIDLSVGRLGISMLEVTQDMIYSKT
                     NTLKDTYIFSLADSLAMAIIDAPKVIMRVANVKSFKLIEQQDRLIAKAEVYRNIDKKH
                     YVKVVINNKAQEQIFRGKFIFEELD"
     gene            3041..4063
                     /gene="plsX"
                     /locus_tag="KRH23_001012"
     CDS             3041..4063
                     /gene="plsX"
                     /locus_tag="KRH23_001012"
                     /EC_number="2.3.1.274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043811 - phosphate:acyl-[acyl carrier
                     protein] acyltransferase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HHS5224301.1"
                     /translation="MKIVIDGMGGDNAPKSNVEGAVNAIKEYQVDLIITGDKDLLEKE
                     FSNYEFDRNKLEIVHTTEIIENEDKPVKAIRSKKDSSMVVALNLVKEGKADAIISAGN
                     TGALLAGGLFVVGRIKGIDRPCLCSAIPNVKRGMTLIADCGANADCKPKNLVEFAAMS
                     NIYSRKVLGLENPKVALANVGLEEGKGNDLVKRSYEEIKKLDLNFIGNVEAREVINAY
                     TDIIICDGFTGNILLKSAEGVALSVMSLIKETFMASTKSKIGALLIKDDLRKLKSFID
                     YSEYGGAPLLGLNGGVIKAHGSSDAKAIKNAINQGIKFSKGKVVEDINQFISKYNEEN
                     KNNEDE"
     gene            4089..5075
                     /locus_tag="KRH23_001013"
     CDS             4089..5075
                     /locus_tag="KRH23_001013"
                     /EC_number="2.3.1.180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0033818 -
                     beta-ketoacyl-acyl-carrier-protein synthase III activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase III"
                     /protein_id="HHS5224302.1"
                     /translation="MNTKAGILGVGSYLPEQSYDNFHFEKIMDTSDEWISTRTGIKER
                     RFAKESEATSDLASKAALKAIECAKLNVEDIELIILATITPDMSLPSTACIVQDAIGA
                     VNATAFDISAACSGFVYGVTIAKQFVETGCYKNVLVIGAETCSKFLNYDDRTTAVLFG
                     DGAGAAVIGPVNEGGILSTHMGSDGKGKDCLKVPAGGSRLKASKETVEANLHTIEMAG
                     SDVFKFAVRKMAETSLRALEKANLNTTDIDYLVPHQANIRIIQASSKRLELDMKKVYV
                     NIDKYGNMSAASIPVALDEAYREGKIKKGDNVVLVGFGGGLTWGASVVKWTL"
     gene            5184..6113
                     /gene="fabK"
                     /locus_tag="KRH23_001014"
     CDS             5184..6113
                     /gene="fabK"
                     /locus_tag="KRH23_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0018580 - nitronate monooxygenase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HHS5224303.1"
                     /translation="MNKICKILNIKYPVIQGGMAWVATASLASAVSNAGGLGIIAAGN
                     APKEAIKKEIVECKKLTDKPFGVNVMLMSPFVDDIIDLIIEEKVQVITTGAGNPAKYM
                     DRLKEAGTKVIPVVPTIALAQRMEKLGATAVIAEGTEGGGHIGELTTMVLVPQVADAV
                     NIPVIAAGGIVDGRGIAASFALGASAVQVGTRFICSEECSVHSNYKNLVLKAKDRDAI
                     VTGRSTGHPVRTLKNKLSKEFLKMEQNGATPEELDKKGTGALRFATVDGDIEKGSFMA
                     GQSAAMVKEITPCKEIIEAMVNQAREIMPAIEL"
     gene            6129..7079
                     /gene="fabD"
                     /locus_tag="KRH23_001015"
     CDS             6129..7079
                     /gene="fabD"
                     /locus_tag="KRH23_001015"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004314 - [acyl-carrier-protein]
                     S-malonyltransferase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HHS5224304.1"
                     /translation="MGKVALVFPGQGAQYVGMAKDLYENNTVAKSVIDEASDALNMDL
                     KNLMFNGNEEELSKTENTQPAMVTHSVAVLKAVQAQIDLKYNACLGLSLGEYSALVAA
                     DAIDFKDAVCLVKKRGKFMQETVPAGVGAMAAILGLDRNVLENVVKDIQGGIVEVANY
                     NSPGQIVISGENEKIEEAMVKCKEAGAKRAVKLNVSGPFHSSMLKEAGVKLASELEKV
                     NITKPKVDVVANVNADYYKNEGKDLLIKQVSSSVLWEDSIERLLNDGYDTFIEMGPGK
                     TLKAFIKKIASNKKANVNIYNIDGIDSLNEFVQNYRNGEI"
     gene            7079..7828
                     /gene="fabG"
                     /locus_tag="KRH23_001016"
     CDS             7079..7828
                     /gene="fabG"
                     /locus_tag="KRH23_001016"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004316 - 3-oxoacyl-[acyl-carrier-protein]
                     reductase (NADPH) activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HHS5224305.1"
                     /translation="MINLTGQVAVVTGGSRGIGKEIAKKLASFGADVVINYTSKEDEA
                     LKTKNEIESMGVKCTSIKCDVSKFDEVNQMIDSVVSEFGKIDILVNNAGITKDGLLMR
                     MKEEDFDRVIDINLKGVFNCTKAVTKPMMKKKYGRIINMTSVVGIMGNAGQTNYCASK
                     AGVIGFTKASARELASRNININAVAPGFIETDMTKVLSDDVKESTLANIPKKSYGKPE
                     DVANAVAFLVSDMSSYITGQVINVDGGMVMQ"
     gene            7882..8106
                     /gene="acpP"
                     /locus_tag="KRH23_001017"
     CDS             7882..8106
                     /gene="acpP"
                     /locus_tag="KRH23_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000036 - acyl carrier activity [Evidence
                     IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HHS5224306.1"
                     /translation="MFNKVVEIIIEQLGVEDKEITMETSLMKDLEADSLDAVEIIMAL
                     EDEFGIEIPDTEAENFKSIGDIVKYIEANK"
     gene            8135..9373
                     /gene="fabF"
                     /locus_tag="KRH23_001018"
     CDS             8135..9373
                     /gene="fabF"
                     /locus_tag="KRH23_001018"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HHS5224307.1"
                     /translation="MNKRVVITGLGCVTPLGTGKEEFWSNIKSGVSGIDKITNFDAST
                     YQTQIAGEVKNFHPEEYISKKELKRLDKFAQFAIVSAKLAVEDANLDLDKVDRERFGV
                     IIGSGIGGVEAIETQHKILLEKGNKRVSSLFVPMMIGNMAAGQVSIFLGAKGPNTNVC
                     TACASGTHSIGDAFKVIQRGDADIMVAGGSEAAVTGLAFAGFCNMKAMSTRNDDPKTA
                     SRPFDKDRDGFVMGEGAGIVILEDLEHALARGAKIYAEVVGYGLTADAYHMTTPAENG
                     EGAARSMNMALKDGNVPLEEVDYINAHGTSTYYNDLYETMAIKTVFGEKAYDLCVSST
                     KSMTGHLLGASGAIEAVVCAMSIEDSFVPPTINIQEVGEDLDLDYVPNQGKEKNIRYA
                     LSNSLGFGGHNATIVLKKYV"
     gene            9599..11317
                     /locus_tag="KRH23_001019"
     CDS             9599..11317
                     /locus_tag="KRH23_001019"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0052621 - diguanylate cyclase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat-containing diguanylate
                     cyclase"
                     /protein_id="HHS5224308.1"
                     /translation="MNFRLPKKRLPKKIIFICIILISIILFIKYDQNGLKEREIINKG
                     KYMSESLVADKEYDEAKKVVKTSFESIPEKKYNKVYNEVWDMLKTISYVPDGTKIVID
                     SLEKMRESDVKLSDECRFNIEKRLASVYIMDNNYSKAVDLTVKSIKLAEKLGNNYEKA
                     RLDVDLASIFLKIGGYETGEKLIKDSFKIDIDEGEKNGMVRLYAIINLAEIYVEEGEY
                     DKAIEISSRIKDYKKFVNTDNYNDFDIMASIMQSNAYVGKNNIQKAKTFLEKADYLIK
                     SDRTVYILDKDMYYYMAMGNLEYKSENYNSAIDNYKKSLEISTKRKLTQEKIKNLNKI
                     LNIYEKQGNIESLNEYQKMLINEYKENKSIRDSETSFYIIDKVSNESKLFEKTKKEIK
                     YYKILFTVILIAILGSTFLYNRLKYFKAQNLHDGLTNVYNRKSFDIMYEKYRDKDDNF
                     ALVMIDIDNFKLINDNYGHKFGDTVIKGITNTICVMLEQDDKVFRYGGEEFSVLIRNK
                     SGEEVADIIDSIRVAIANKKWNDDVTVTISAGVAHVSDSKDVLEEADKNLYKAKQLGR
                     NKVVYK"
     gene            11348..13348
                     /locus_tag="KRH23_001020"
     CDS             11348..13348
                     /locus_tag="KRH23_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HHS5224309.1"
                     /translation="MKQSIAIVTDKITKLSSFLEENIRLVLGNYIDINHYYLEVLKEN
                     DKIQGNFVLVMNDDRLNSMRKHLVQDSKIIVIRRTLKENEIYGLFSIPNGTEVLVVND
                     TKETTLETISLFYKIGVKNLKFTPYIEGKIYKNIDIAITPGVKGKVPSYINKVIDLGN
                     RYIDISTFIEIINGLRIDVKEIRKNLMAYSESLISLDNGVKDNYRQLFLKIEEQDVIL
                     NLSKDGIIFTSADGIINTFNKEALKILGINENPQGKNIEDIISEDLNILLEDKEIIDE
                     VVFTNKKYINVNKKSIFSMGNKAGIYYNLQEITYIKKLEQNLTNKLREQGQIARYTFK
                     DIKTKNKNMVKCVELAKKISKSDLSVLIIGESGTGKELLSQSIHNASNRSNQPFIAVN
                     CAAVPDSLLESQLFGYEKGSFTGALREGKKGLFELANNGTIFLDEIGDMPPLLQTKLL
                     RVLQEKQVMPIGSHNVINIDVRVIAATNKNLLKMIREGKFREDLYYRLNVLPIDVPSL
                     RNRKEDIITLMNFFLKNNIRLSPEVITILEKYNWPGNIRELQNVASYVSLMCDSMVFR
                     DDLPPYIRVECANNYEDGFGYTRKEFEEILRILYERRESSSGIGRGFIIEKLIQEGIE
                     ISESKVRKVLSYLSECGYISSKSGRGGSQITSEGIKLYNNIN"
     gene            13699..13944
                     /locus_tag="KRH23_001021"
     CDS             13699..13944
                     /locus_tag="KRH23_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03905 family TSCPD domain-containing
                     protein"
                     /protein_id="HHS5224310.1"
                     /translation="MKYKTTGTCATEIEFEVKENKVTNVNFIGGCDGNLKGLKVLVEG
                     MNIEDVIQKLKGIECKTKPTSCPDQLSLALENYMNIK"
     gene            13979..14704
                     /locus_tag="KRH23_001022"
     CDS             13979..14704
                     /locus_tag="KRH23_001022"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0016811 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds, in linear amides
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HHS5224311.1"
                     /translation="MKPIIGILGNLIIMENGMFPGLERSYVNNDYINAVLKGGGSPVI
                     IPVNTDKEVIKKQIEMVDGVLISGGWDINPQLYGEETREETTFIYPEVDEFDLIAISI
                     ALELKKPILGVCRGLQILNVSLGGTLYQDNNLIEGSYIKHTQSSKRHVATHKVDVKEG
                     SILEGILGKQLLTNSYHHQSVNQLGKGLKAIAYSKDGIIEAIEKEDENFVVGVQWHPE
                     MMVDYCDKMEKLFKYFINICSNL"
     gene            14726..16039
                     /locus_tag="KRH23_001023"
     CDS             14726..16039
                     /locus_tag="KRH23_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015171 - amino acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HHS5224312.1"
                     /translation="MNEKNKMGLISIILLGINAVVGAGVFLLPGDAMKSFGVASIFVY
                     IFDMLLVLSMAFCFAEVAGKFNKNGAAYVYTKEAFGDFCGFEVGLMKWVIGCISWGAL
                     IVGFPTSLSAVWAPAGEPHIQKIIIVAMIVGLTIINLLGVSLSKIVQNVITVGKLIPL
                     ILFIGIGIFFIKGVNFTSSTMVPPGAGATEFGAAALLMFYSFTGFESIAVAAEDMENP
                     QKNIPIAIISVIVIASIIYILNQVVCVGILGDSLSSTSTPVADAARICFGNMGAGLVT
                     FGTLVSVGGICMCGAFVNPRSCVALADDKMLPRIFARKDKKGTPYVAIIATMLITIPI
                     ALSGSFAELAAISAVARFIQYIPTSLSVLVFRKKRPELVGTFKTPFGAVIPLIAVCVG
                     TWLLFQASMHQLIMGLGALAIGVPLYFIMKSYNRKVYGENLKKIV"
     gene            16245..16784
                     /locus_tag="KRH23_001024"
     CDS             16245..16784
                     /locus_tag="KRH23_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase family protein"
                     /protein_id="HHS5224313.1"
                     /translation="MPTITLKNGVDVLIREGVREDAQSIIDFYNEVGGETHFLSFGKD
                     EYKISLEEQENAIESAKASDNSVKLIAFIDGEIVGIATIDSNQKAKGKHVGVLGIVVK
                     EKYWGIGLGKRLMLDLIEWCKSNGITKKITLVTNEENYNAIGLYKKVGFEVESILKKE
                     CYYNGVYTDLIGMSLLLGI"
     gene            16873..18858
                     /locus_tag="KRH23_001025"
     CDS             16873..18858
                     /locus_tag="KRH23_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-1,6-bisphosphatase"
                     /protein_id="HHS5224314.1"
                     /translation="MKNLCKISDDYLNSKLKYLKLLSKQYPSISKASTEIINLEAILN
                     LPKGTEHFITDVHGEYEPFVHVLKNGSGVIKRKIEELFSNTIRDSEKKMLATLVYYPE
                     QKLDLIIKQEENIDDFYRINIYRLIELCKYASSKYTRSKVRKLLPENFKYIIEELLHE
                     HVKSEHKEEYYKSIVETIVDIGIAKEFIIAISTVIQKLVVDRLHVIGDIYDRGPRPDI
                     IVDKLIEHHCVDIQWGNHDILWMGAASGEKTCIANALRISARYANLDIVEDIYGINLL
                     PLATFAIEMYKDDPCKEFIPKVNDQSVTTTEKSLMAKMHKAISIIQFKLEGEVIRRRP
                     EFEMEHRLLLNMINYDEGTINLKGKTYKLKDTYLPTIDKKDPYKLTMEERNVIDKLVS
                     SFRGSEKLQKHVSFLFSKGSIYLKANSNLLIHGCVPLNEDGSFMSMNIMGKEYKGKAL
                     MDKMESLAREGFFFKDKAEEKLYGMDIMWYLWTGKCSSLFGKDDMTTFERYFIAEKET
                     HKENKNPYFKLRENEMACKRLFEEFDLELDESHIINGHVPVESKNGESPIKANGKILV
                     IDGGFSRAYQKTTGIAGYTLIYNSRTLQLVSHEPFNSAEEAIANESDILSTTVVVEHK
                     AKRKMVRDTDEGIKIQEEIEDLKLLLMAYKKGLIKEM"
     gene            19082..20050
                     /gene="spoIIIAA"
                     /locus_tag="KRH23_001026"
     CDS             19082..20050
                     /gene="spoIIIAA"
                     /locus_tag="KRH23_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AA"
                     /protein_id="HHS5224315.1"
                     /translation="MNKLSDEIINSLSTTIREKVEKVSNNNLNIEEIRLRSQKPLILN
                     ANSKDYFYNQKTMTLDLNQQNSYVVTREDVEQTFQIICKYSIHSFMDDIKKGFITLRG
                     GHRVGLVGKAIVEDGQVKNIKHISSLNIRVSREIIGCSDKILSHIIKGKNQINNTLII
                     SPPQCGKTTLIRDIVRNLSNGNEDYGFKGLKVALVDERNEIAGAYLGVPQMDVGIRTD
                     IIETCPKDLGITMLLRSMSPNVIVTDEIGSEKEIKALYTALNGGIGLITTVHGDSIED
                     IQNRKELNRLLDKELFKKVIILSAKRGAGTIEKIYDLEEKRWYFAN"
     gene            20040..20561
                     /locus_tag="KRH23_001027"
     CDS             20040..20561
                     /locus_tag="KRH23_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AB"
                     /protein_id="HHS5224316.1"
                     /translation="MQIKIIIIAFLIGSSYLIGEQIYKTYTRRHKQLNDLIRVLEILR
                     MDLSFGLYTLEEIFNRIGGNKEFCFWKFFYQISEGLHNEQSKTLEIIISENIDVLSKE
                     TYLGNKEIEELKNLILTLGKSDIESQQRMIDLSIENLKKQTYETKEDINKKGVLYKKL
                     VTFIGIGICIILI"
     gene            20578..20775
                     /gene="spoIIIAC"
                     /locus_tag="KRH23_001028"
     CDS             20578..20775
                     /gene="spoIIIAC"
                     /locus_tag="KRH23_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018589775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AC"
                     /protein_id="HHS5224317.1"
                     /translation="MEISLILKVAGVGILISVLNMILEKTDRKDWAGLTTLAGVIIVL
                     GMVITEISDLFNTVRTMFQLY"
     gene            20800..21177
                     /gene="spoIIIAD"
                     /locus_tag="KRH23_001029"
     CDS             20800..21177
                     /gene="spoIIIAD"
                     /locus_tag="KRH23_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AD"
                     /protein_id="HHS5224318.1"
                     /translation="MQLIGIAIISTTLCLVIKKDRPEIANFIAIITGVIILLSVMFKL
                     NFIVDSIQDLANKANIPTMYISLIIKLIGIAYLMEFAIQLCKDCGEGNIASKLEFGGK
                     IIVMSMSFPILLSIVEMVVNIIP"
     gene            21262..22467
                     /gene="spoIIIAE"
                     /locus_tag="KRH23_001030"
     CDS             21262..22467
                     /gene="spoIIIAE"
                     /locus_tag="KRH23_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AE"
                     /protein_id="HHS5224319.1"
                     /translation="MKKRFLPMIIGFLFTFFFVNIFAIMIFANEVPSSEDKEYGETKN
                     SIDKYIDGQLDKLDINEIQDYINKEIVINDVNLKSFVKDLISGEKNILDLFNKDGLKI
                     LMFDEFKASLKVVAVILVLALLSSILKSLENSFSSGAVSQIATYIIFITMVSLTLIGF
                     KDVLQICYDAIDHTVGLMQVIMPILITFLLLIGFPITSTTLNPIFIGGVTFINVFFKN
                     FLFVSITVAFGILIINNLSKNIRLKRFFSFVKQINYVSIGAMFTVYLGLVSIQGLYVT
                     SFDKFSVKTAKFAIGNFIPVVGGFVSDSVDILLSSSQLIKNIFGGIGLILLVGICLLP
                     VIKILSVIVVYKLAAIIVEPVGEDGISNFLNEVANLMIIMLASVIAITVMFFVTVAIL
                     TSISVVSQG"
     gene            22527..23144
                     /locus_tag="KRH23_001031"
     CDS             22527..23144
                     /locus_tag="KRH23_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AF"
                     /protein_id="HHS5224320.1"
                     /translation="MLEGIKAWIVSVLIGAFIVNIVDMILPSSKIKPYVNLVLNFMFV
                     FIVITPVVGFFSKDMSLEDRILKSMGNYNKQYVDSTNALAKETGNNSLSKGYEDGLKE
                     VLKLKLDEYGYDLEDIELNGANINNIKIKEKNNSAKSNNSSNEENKNNSTKREEENIN
                     SNDKENSKQVFKKGTEYGLNLNEEKLKNDLIKVLDVSIEDIQIDK"
     gene            23156..23710
                     /locus_tag="KRH23_001032"
     CDS             23156..23710
                     /locus_tag="KRH23_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AG"
                     /protein_id="HHS5224321.1"
                     /translation="MLKNLNDKDKRKVYSLITIAGICVVSLVLLSCFPSSKSDKQVGK
                     TETNKNAEKQVTKEQEKDDLESKLTAILSKIDGAGDVDVMVTFESSEEIQPAFNSNNT
                     TETTEEKDAQGGERTVTTSSENKTMITSNSSDPVVIKTTEPKIKGVIVVASGASDPSV
                     KETLYSAVQTSLQVAGHQVEIYSK"
     gene            23737..24426
                     /locus_tag="KRH23_001033"
     CDS             23737..24426
                     /locus_tag="KRH23_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpoIIIAH-like family protein"
                     /protein_id="HHS5224322.1"
                     /translation="MKFNYKGRGFVIITLTAMLVVVGTVNYQLSKKSLLETSKEFKAY
                     EEAQLQKNTDDSDSSKTEDSSNVDKQGGKESADIDIVDSKASKVKEKATETSKEIKAQ
                     LSSEKNMKKASYILDMKMNREKQRNELVQDLNEMINNPSTTEESRKEASNMKLNIVKI
                     QEKELQIENLLSTKGYEEALVYISDNKVNVVVNEAKLEKKDAAKIFDLVAEQANVKYE
                     NIKLTNNNSNK"
     gene            24536..24898
                     /locus_tag="KRH23_001034"
     CDS             24536..24898
                     /locus_tag="KRH23_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HHS5224323.1"
                     /translation="MEDNKFGQVKISNDVIATIAGLAALEVEGIETTATLTDKLLKNN
                     GVKIQIEEEDVNLDVMVTIKYGMSIPDTAFKVQENVKNTVETMTGLKVSQVNIHIQGI
                     SFKKDKVDKEEAKATKKN"
     gene            24983..25489
                     /gene="nusB"
                     /locus_tag="KRH23_001035"
     CDS             24983..25489
                     /gene="nusB"
                     /locus_tag="KRH23_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HHS5224324.1"
                     /translation="MKKDRAQKSTTREYIMKLIYQININKEDFETLEDKVDNFLKDNS
                     EHIINRYKELALQYSKNTNLKLEDTEIEDVIDKKYINTVCKALKENHDKIDELINKHA
                     KNWTVDRMPKVDVSILRLSVCEILYLDTPNKVSINEAVELAKIYCDDKSPKFINGILG
                     SVVDEIGK"
     gene            25473..26543
                     /locus_tag="KRH23_001036"
     CDS             25473..26543
                     /locus_tag="KRH23_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-sialoglycoprotein endopeptidase"
                     /protein_id="HHS5224325.1"
                     /translation="MKLGNNIIIGIDTSCYTTSIAAISLDKKVIFNEKIMLEVRDNSK
                     GLRQSEAVFQHINNLGILSDRIKSFKDKFNVEGVCSSKKPRPVENSYMPVFNVGHNFG
                     KLLSSIYGCRFYETTHQENHIEASLLNSKLKNNNKFISVHMSGGTTEILLTSKQDSHH
                     NVCDTNLGKIAKISIKKDDKSKLYNNFGYNIDIIGGSKDISFGQLIDRVGIKLGYKFP
                     SGKYLDENALNCNLKIESGLKTSVRDGYMNLSGLENQVNKIINDNGDNTNQKEYISKL
                     VLDSVVRNMFKSLVYLCETYNVNEVVFAGGVSASKYILRELSMKLRKKHIEAYFTEPQ
                     YSTDNAVGCAIIGLNNFLGERV"
     gene            26540..27745
                     /gene="xseA"
                     /locus_tag="KRH23_001037"
     CDS             26540..27745
                     /gene="xseA"
                     /locus_tag="KRH23_001037"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA];
                     GO_function: GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA];
                     GO_process: GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HHS5224326.1"
                     /translation="MKLRALDISEANSYIKRILINDPILSNLKVKGEISNFKVHSSGN
                     VYLSLKDETSKLNCVIFKSNFNRNLKLDNGVKIIANGYISVYERDGAYQLYINEIEIE
                     GIGNLHIEFNRLKEKLNKEGLFDPKYKIPIPKMPNSIGVITSPTGAVIRDIINVIKRR
                     YPKVNIKLYPVTVQGDKSAEEICEAIRFFNHMKNVDTLIVGRGGGSIEELWSFNDEMV
                     AREVFNSQIPIISAVGHETDFTICDFVSDMRAPTPSAAAEIATPSLDDINYKLGNIKS
                     RMSKSLTNQIELDQYRLETVFNKINNYLDSYTIKDKVIQLDKIYDKIIFGIENNLKLE
                     DEKLVKIGALLHNLSPLATMDRGYSITQKNGKVINSIKGLKIKDSIDIVLKDGNLECM
                     IDKIENKEG"
     gene            27747..27962
                     /gene="xseB"
                     /locus_tag="KRH23_001038"
     CDS             27747..27962
                     /gene="xseB"
                     /locus_tag="KRH23_001038"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA];
                     GO_function: GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA];
                     GO_process: GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HHS5224327.1"
                     /translation="MNLTYEEAYKRLESILSELESKNASLDESLSLYEEGISLYKHCN
                     KLLDDAKLKISKFNQLGIEEDFKIEEE"
     gene            27965..28852
                     /locus_tag="KRH23_001039"
     CDS             27965..28852
                     /locus_tag="KRH23_001039"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004659 - prenyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HHS5224328.1"
                     /translation="MEFKQCLKEKASFVEKVLKEYMPKEEGYQKTVIEAMNYSLSAGG
                     KRLRPILTLEACKIVGGNEDEAIPFAIAIEMIHTYSLIHDDLPALDNDDLRRGRPTNH
                     KVYGEAMGILAGDALLNYAFEVMLAGSINKENPEKYLKAINEIAKGAGIYGMIGGQVV
                     DVESENKQIEKEKLDYIHMNKTAAMMVGCMRAGATIGGANSEQMEEITKYAKNIGLSF
                     QIVDDILDIVGDEAKLGKKVGSDIENHKSTYPSLLGLDKSKEIAHNLIDEAKKSIEKL
                     SDDVDFLKGLAEYIIDREY"
     gene            28882..29319
                     /locus_tag="KRH23_001040"
     CDS             28882..29319
                     /locus_tag="KRH23_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divergent PAP2 family protein"
                     /protein_id="HHS5224329.1"
                     /translation="MDFFSEIFNNGALGISLIACFLAQFIKIFTGKEKRIELSRILIS
                     GGMPSSHSSFVTSLATVVGIEKGFNSTDFAIITVLALIIMYDAAGVRRAVGKQATILN
                     QMVADIQHGKHIEQKKLKELIGHTPLEVWFGALLGIVTALILM"
     gene            29353..31218
                     /gene="dxs"
                     /locus_tag="KRH23_001041"
     CDS             29353..31218
                     /gene="dxs"
                     /locus_tag="KRH23_001041"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008661 - 1-deoxy-D-xylulose-5-phosphate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0008615 - pyridoxine biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009240 - isopentenyl diphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HHS5224330.1"
                     /translation="MYKYLDKVNSPKDIKNMSIEEMDLLAKDIRKFLVKSVSKTGGHL
                     ASNLGVVELTLALHKVFDSPKDKIVWDVGHQSYVHKIVTGRKDCFVSLRQFNGLSGFP
                     KENESPHDIFDTGHSSTSISIATGIACARDIKKENYSVISVIGDGSITGGMALEALNQ
                     LGYIDTNMIVILNDNEMSIDKNVGGMSKYLSSIIRNSTVEKMTDEVDKILNVTQTGEI
                     LSKTAHRFKDKLMYSFSPQDCSFFDSLGIRYYGPIDGHNTKELIDILRKAKHKKGPVL
                     LHVITKKGKGYRFAEEQPDKYHGVSKFDIKTGVTSAKVKSMSISVGEKLVDMANSNEN
                     IVAITAAMPSGTGLNLFESAYPKRYYDVGIAEQHATGFAAGLAKNGMKPYFAVYSSFL
                     QRAYDQVIHDVCITKKPVTFLIDRAGLVGNDGETHHGMFDLSYLNSIPNIVVMAPKDT
                     REMELMMDLSLKLDCPLAIRYPRGSSYYLDKGEYGEIVLGKYEVLDDGQDTVILCIGS
                     MVKHALEAKEILSREGINPTIVNARFLKPIDEGMLKALLKNHKNVVTIEDNIVTGGFG
                     SRINKFIIDNEYNVNILNIAIPEEFVKHGNIDELYDFVGLSPKSIADKIRKLVIE"
     gene            31351..32163
                     /locus_tag="KRH23_001042"
     CDS             31351..32163
                     /locus_tag="KRH23_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family rRNA
                     (cytidine-2'-O)-methyltransferase"
                     /protein_id="HHS5224331.1"
                     /translation="MKKRIDLLLVEQGYFESRERAKKAIMAGLVFVDNQRCDKAGTEV
                     KEDCSIEVKGNPIPYVSRGGLKLEKAMKNFDLTIDGKVCMDIGASTGGFTDCMLKNGA
                     IKVFSIDVGYGQLAWKLRQDDRVVCMERTNIRNVTIEDTKQFADFASIDVSFISLKLV
                     LPKAKELVRHDGEVVALIKPQFEAGREKVGKKGVVREKSTHIEVIKMISDFSVENGFE
                     ILGLDFSPIKGPEGNIEYLIHLRNGNEGYEFDGETYNNKIVEVVEASHNLDK"
     gene            32183..33862
                     /gene="recN"
                     /locus_tag="KRH23_001043"
     CDS             32183..33862
                     /gene="recN"
                     /locus_tag="KRH23_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HHS5224332.1"
                     /translation="MILELYMKNCALVEELRLNIDKNLNILTGETGSGKSIIIDALGL
                     CLGDKYDRSFLRKGTDKGLVEAVFFSDNRYLKKILEENDISMEDDNLLVITRLIYSDG
                     KSTARVNGRTVKVSLLKEIASTLIDIHGQHQNQALFNKDTHLKFLDLFGENELEEFKI
                     AYKNVYHKYSEVKKALNCLTENKDEMQIQREIDLLRFQINEIEAANLNKNEYEDLLKQ
                     REVYRNSEKIYNNLNSSYSKLHNGEYNVIDLIGLASKELNDISKYDSVLSEYSDTVER
                     IMYELQDISGEIRNYKDNIDFEPYELEQIELRIDEINNLRRKYGDSIDDIFEYYGKIK
                     DRLDEILNRDERVEQLRSKLMNIEEDLKIKASKLTKARIEVATTLEKILLDELKSLNM
                     KNVMFKVNFEKGPFTLDGVDDIEFMISFNLGEDIKPIYKVASGGEMSRFMLAFKTILA
                     DIDDIDTLVFDEIDTGISGIAAQIVGEKLSDIAKKKQIICITHLPQIAANADTHYCIE
                     KDTSNNRTFTNVSKLNESQRKNEIARLIAGNNITEKTIEHASEIIELAKKC"
     gene            34076..34942
                     /locus_tag="KRH23_001044"
     CDS             34076..34942
                     /locus_tag="KRH23_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224333.1"
                     /translation="MNKKDTMHLIFTIVIFILLWYIVVAVSEINKNIESCSNKLDYLS
                     QEIMSTKSDISNTINEEMSKSYITKSIDLKVKKIEKKECVIDVDVQLSKLGKNGKVFF
                     MYKEDSDKWNETEMTKHGELSYACEIKINTGSEYDYKVVTSGAISESSDVQKLTKSDY
                     MPEQPIFNSGIRDNREYFIEIVENSNLFNHESEKSKNKVYDNIRLEKVDIIVNEGKKD
                     TIYKAKLAEGLDDGKTNNSNRNQVNYEVSFPKRDIDGIIYIKAKLTYNNGVEYTKDIT
                     EDITMGLQDLEK"
     gene            complement(35035..35526)
                     /locus_tag="KRH23_001045"
     CDS             complement(35035..35526)
                     /locus_tag="KRH23_001045"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HHS5224334.1"
                     /translation="MADKMAQNITLQFVEEKDLENLENVKLLFTEYSNSLNIDLCFQD
                     FNNELKTLPGKYKKPSGSLILAFVDENLAGCVALKKLEGKICELKRLYVRNQFRGLKI
                     GKILLEEIIEEAKKFGYTHMRLDTLPSMKSAQGLYEKFGFYDIEPYTYNPIEGARYME
                     LKL"
     gene            complement(35587..36027)
                     /locus_tag="KRH23_001046"
     CDS             complement(35587..36027)
                     /locus_tag="KRH23_001046"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HHS5224335.1"
                     /translation="MKLNVRIADINNWHDLVSLSVDKSQLDYIESNALSIAESKFITA
                     WVPVGIYDENSLIGFAMYGRLEDDRVWLDRFMIDSKYQGKGYGKASLDFLVNHLKNEY
                     NCDELYLSIFEDNKMAIKLYKDFGFEFNGELDYGGEKVMVLKSN"
     gene            36188..37246
                     /locus_tag="KRH23_001047"
     CDS             36188..37246
                     /locus_tag="KRH23_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpoIVB peptidase S55 domain-containing protein"
                     /protein_id="HHS5224336.1"
                     /translation="MNKINKNFKNIWIILGAVSIFTMVIIFNKNCNVNKETQIEAFTI
                     KNHDKKFVYPMGNIIGVKANTDGVLVLGYEEEDVDYIGGIQIGDNIVKIDNKRIKNSQ
                     DVSEILNKIKKSKVEVTFERKNKYKTEVIETKKENGKYKLGLWVRDKISGIGTMTFYD
                     PSMEKFKAIGHAIKDSDTNELLKIKQGYIYKPEQLKIVKASNEKVGKIKGDFNDSNLM
                     GNFSNNSELGISGNITENHNKEFNVANKEKQLIEVGRPQDVKIGDAVILFEDKNKNIT
                     SYDIKIESIVYDKGNYRDMVIKVVDDKLLEYTGGIVQGMSGAPIIQNNKIIGAITHVF
                     RDNPKKGYGIFIDEMIKL"
     gene            37388..38212
                     /gene="spo0A"
                     /locus_tag="KRH23_001048"
     CDS             37388..38212
                     /gene="spo0A"
                     /locus_tag="KRH23_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005509 - calcium ion binding [Evidence
                     IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0042173 - regulation of sporulation
                     resulting in formation of a cellular spore [Evidence IEA];
                     GO_process: GO:0043937 - regulation of sporulation
                     [Evidence IEA];
                     GO_process: GO:0051606 - detection of stimulus [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation transcription factor Spo0A"
                     /protein_id="HHS5224337.1"
                     /translation="MGGFLVEKIKIVLADDNKDFCQVLKEYLSNEDDIDILGIAKDGI
                     EALDLVKKTQPDLLILDVIMPHLDGLGVIEKLNTMDIPKMPKIIVLSAVGQDKITQSA
                     INLGADYYIVKPFDFVVFINRIRELVSNRVTQVEPKPRPVQETQMTRSDFVKNVGNIE
                     TEITNIIHEIGVPAHIKGYLYLREAIKMVIDNVELLGAVTKELYPSIAKKFNTTPSRV
                     ERAIRHAIEVAWSRGKVDTINQLFGYTVHNTKGKPTNSEFIAMIADKLRLEHSMVK"
     gene            38625..39746
                     /gene="steA"
                     /locus_tag="KRH23_001049"
     CDS             38625..39746
                     /gene="steA"
                     /locus_tag="KRH23_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative cytokinetic ring protein SteA"
                     /protein_id="HHS5224338.1"
                     /translation="MRVEAPIKVDRKTKKLAKRVESGEIAVINHIDIDEVAANSLVEA
                     KIKLVINAAPSISGRYPNKGPGILTENNILIIDNVGEELFEELKEGETIEVVDGKIYR
                     KGKFLGAGEVLDKYEVSHQIKAAYENLAVELDRFIDNTIDYAKKEKGFILGEVEIPKV
                     KTNYANKHVLIVVRGQDYKEDLSTMLSYIEEVKPVLVGVDGGADALIEFGYTPDVIVG
                     DMDSVSDEALKKASEIVVHAYTDGRAPGLKRVEELGLDAVVFPAPGTSEDIAMLIAYE
                     YKAELIVAVGTHSNMIDFLEKGRKGMASTFLVRLKIGSKLIDAKGVNLLYRSKLKIKY
                     IWALIATALFPVLVVASLSPGVQQFIQLMQLKFRVLLQM"
     gene            39764..40639
                     /locus_tag="KRH23_001050"
     CDS             39764..40639
                     /locus_tag="KRH23_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055070 - copper ion homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="copper transporter"
                     /protein_id="HHS5224339.1"
                     /translation="MHINMKYYIVTIGAIFIALGIGMLVGFNLNNNQQLSEQQANIIN
                     DLDDKFNILKEKNDKLDSDLASVNRDYEEAVNFINKNVDKILAGSLNGKSIGIISANE
                     NDDYTKNIEDIINKSNGSIAFNIILKENITNPEKLKEMSTKLGTDVKNANDAVNYIID
                     TLKKEDASDILTYLQELDVIKFNFIGDTYLKYDSVVIAGGNDAKDSTKQFEKIEKFVV
                     SKLKSENKYLVEVQNTGVKTSYVELYSKNKVATIDNIDEGIGSISLAILLQQGNIVGN
                     FGRLDTATSLLPSIK"
     gene            40663..41355
                     /locus_tag="KRH23_001051"
     CDS             40663..41355
                     /locus_tag="KRH23_001051"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HHS5224340.1"
                     /translation="MDSYISIIIPAYNEESRIKYTLESILDIKQINEIIVVDDGSIDN
                     TAKVVSELENEKIKFFKLDKNRGKGYALNYGIKLAMKNADIIGFLDGDLGSSAKEVEK
                     LIVPILNGEADVTIAKFPPAKRKGGLGFVKGLAKNSVFEMTGVELDATLSGQRIFKRE
                     VLEKFDEIPFGYGVEVGMTIDILKYGFKIKEVLVNMTHNETGRNLKGFIHRGKQYYHI
                     KKVLGQKKKEWR"
     gene            41363..42187
                     /locus_tag="KRH23_001052"
     CDS             41363..42187
                     /locus_tag="KRH23_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HHS5224341.1"
                     /translation="MKDYILYTILLLTGLFGTYAVIPLFKNLLINGNVLRPNYKKDMI
                     PVSMGIVFLPMIVINGIILAFFTTEFKNLAYIFMFMFGMISMFFAGILDDVIGNRDVS
                     GLKGHFKSLFKGSLTTGGFKALFGGFVGLIVSVAISKDIIDIIVNTLIIALSTNLMNL
                     LDLRPGRAIKAYLFIMVIIFLTLTGFVQVLPLLIVPNVLAYFNYDLKARAMMGDTGSN
                     VLGISIGMLISFGYPFNIRLGWLIFVVIMHIFTEKYSLTKIIEKNKLLNFIDKLGR"
     gene            42192..43259
                     /locus_tag="KRH23_001053"
     CDS             42192..43259
                     /locus_tag="KRH23_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3866 family protein"
                     /protein_id="HHS5224342.1"
                     /translation="MISKRVGIVESIVSQTETLDDIRVNINGEIQRAYNYPKISGTIN
                     IGDEVVLNTTAVELSLGTGGYHFVITNLNNIESTLTEGGHIMKLRYTPLQIKVDSVEE
                     QESIYHDKFANFKGLEGLSVVVGTLHSMLTPFAASFKRNNPNKKLVYIMTDGASLPIY
                     LSKNVDTLKEKKLIDSTITIGNAFGGDYECINIYTALITAKEILKADAVFVSMGPGIA
                     GTGTKYGFTGIEQGSILDAVKKLEGRAIAIPRISFADKRERHQGISHHSMTVFKEIVN
                     VNVDIPITIYDDEKLNFIKEQINLNGLDKKHNIIYIDNNKTKEDLDYFNLKVKSMGRN
                     YEQDEAFFKAASTAAYYLMEV"
     gene            43261..43797
                     /locus_tag="KRH23_001054"
     CDS             43261..43797
                     /locus_tag="KRH23_001054"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016817 - hydrolase activity, acting on
                     acid anhydrides [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0009132 - nucleoside diphosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HHS5224343.1"
                     /translation="MVLEEKTISSDRVYTGKVITLKVDTVEIPGQGYQKRELVEVGGA
                     VGIVAITDDNKVVLVKQFRKPIEKPIFEIPAGKLEKNESPKECAERELKEETGYSAKN
                     IKLIHKFFTSAGFSNEIMFVYLATGLTPGENNLDADEFLDVYEIELEEAYNMVLKNDV
                     EDAKTSIGLLLVKDMFKN"
     gene            43865..44470
                     /locus_tag="KRH23_001055"
     CDS             43865..44470
                     /locus_tag="KRH23_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein M"
                     /protein_id="HHS5224344.1"
                     /translation="MRRTYRKNDFRELNRQIIIIGLLFMMSIVVGSYINKILPGSSNN
                     ILNNINPAVEYYNLNISIKDTVIQNLKSDAIFMGSIALLSLFVVTIPAVLVAFVLKGM
                     SIGYTINSCILALKFKSIKMILIILFKNLIIIPCAIILALISLSYFKEMVYEFKKKNR
                     KNMQFLIKRYILNIIIIIALSLGLQLILNTASIGIIKFLAK"
     gene            44482..45396
                     /locus_tag="KRH23_001056"
     CDS             44482..45396
                     /locus_tag="KRH23_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HHS5224345.1"
                     /translation="MDIIEGYIDYIKDKKKLSENTVASYFMDIKKYMEYINQKSIKLV
                     DIVENDIISYLIKLEKDNVSIATIARMISSIKSFHDYLFLNHICTNNPAKDIKKPKIK
                     KENINILTEEEIERLLNFPKLTTPKLIRDKAIFEVLYGTGIKVSELVEMNIEDIDLDI
                     DYIYCNSCCKNQRVIPLCDITKLYLEKYLKEARPKMAVEGEKSLFVSSLGQRFTRQGL
                     WKVIKKYSNLANIDKNINPTMLRHSFAIHLLNEGANIAVVSKILGNVNLSSLQVYLNH
                     IDKNVRREIKEKHPRNDVDVELQKAEAK"
     gene            45438..46610
                     /locus_tag="KRH23_001057"
     CDS             45438..46610
                     /locus_tag="KRH23_001057"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008973 - phosphopentomutase activity
                     [Evidence IEA];
                     GO_process: GO:0009117 - nucleotide metabolic process
                     [Evidence IEA];
                     GO_process: GO:0043094 - metabolic compound salvage
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HHS5224346.1"
                     /translation="MSRVIWIVIDSVGIGALPDAEKFGDSKDVSTLGNIFKEYPDIQI
                     PNMRNLGIGNIDGIDFFESIKEPIGCFGKCKEMSQGKDTTTGHWEMTGIIVDKPFKTF
                     EHGFSKEIIEEFEKKTGRKVVGNKPASGTVIIDEYGEHQIKTGDVIVYTSADSVFQIA
                     ANEEVIPLEELYNMCKIAREIMMGDNAVARVIARPFIGKKKGEFVRTSNRRDYSLDPF
                     EPTVLDNIKESGLDVLAVGKIEDIFNGKGITDAIHTKSNMDGVDETLNYMKQDNKGLI
                     YSNLVDFDSKYGHRRDPEGYKKALEEFDSRLPEIMANMREDDILIINADHGNDPTYKG
                     TDHTREYIPVMIYGNKIKKGFNLGVKDTFADIGATVADILNVKLPKHGSSFKGDLF"
     gene            46657..47469
                     /locus_tag="KRH23_001058"
     CDS             46657..47469
                     /locus_tag="KRH23_001058"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HHS5224347.1"
                     /translation="MFEKIAQSSKFINSKSNIKPKIGLILGSGLGDLANDIEDPVTIK
                     YSEIPNFPVSTVAGHAGQLVIGKLEGKEVIAMQGRFHYYEGYSQKEATFPVRVMKELG
                     VEILIVTNAAGGVNKEFKAGDLMLIRDHINFSGSNPLVGKNDDRFGARFPDMSDAYSS
                     KYVDVVKNCAKECNIDVKEGVYMFFSGPNYETPAEVRMAQILGADAVGMSTVPEVIVA
                     SHSNIGVIGISCITNMAAGILNQPLSHEEVIETTQKVKSEFMNLVKTTVKNL"
     gene            47673..48998
                     /locus_tag="KRH23_001059"
     CDS             47673..48998
                     /locus_tag="KRH23_001059"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016154 - pyrimidine-nucleoside
                     phosphorylase activity [Evidence IEA];
                     GO_process: GO:0006213 - pyrimidine nucleoside metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HHS5224348.1"
                     /translation="MRMYDIIKKKRDNLELSKKEINYFIENYSKGDIPDYQASALLMS
                     IYLNKMNKQETVHLTEAMMNSGDMINLSEIDGIKVDKHSTGGVGDKTTIALIPLVASC
                     GAPVAKMSGRGLGHTGGTIDKLESIPGFSTEMEISKFIDSVNKSKIAVCGQSAKVAIA
                     DKKIYALRDVTATVDNISLISSSVMSKKLASGADAIVLDVKTGDGAFMKTLEESFELA
                     KSMVDIGTGMNRDTIGIVTDMDEPLGFAVGNSLEVIEAIETLKGNGPKDLVELCEVLG
                     AYMLVLSKIAHDFEDGVEKIRESIKSGTAIQKLKEFIENQGGNKDVVDDYSLFKKSKY
                     KYPVKSTKSGYISKIKAEDVGVSAMILGAGRETKDDILDLSAGIILEKKVGDYVNEGE
                     VLAYMYYNDEQKLSLAKGRFIDSYSIVDSKIEKNKLIYGIVTKEEIKKF"
     gene            49211..50290
                     /gene="mltG"
                     /locus_tag="KRH23_001060"
     CDS             49211..50290
                     /gene="mltG"
                     /locus_tag="KRH23_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008932 - lytic endotransglycosylase
                     activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HHS5224349.1"
                     /translation="MNFKENRLKIAVLIIVILIILAGIFVFIQIGPYDKNNKKDVIID
                     VPNGASVGKISDILYENKLIKNELLFKLLVKVSNKAPSIKSGTYLLNQSYSNNDIISL
                     LVSGKIYQDGIKVTIPEGATSKEIIAMLVSKNLGDKATFENLIKKPQEFYDKFPYLKE
                     DGITSLEGFLYPETYYFNSKKQSEEDILSEMLKVFDSKYTDKFKKKQKELNMTLQEVM
                     EMASIIEKEAVLDKDRPIIASVFYNRLKVGMPLQSDATIQYIFEERKKIVTYDDLKID
                     SPYNSYKNKGLPPTPISNPGIKSIEAALYPEKTDYLYFVAKIDGGNNYSTNYQDHLKY
                     VKEYKEARDKQSKDTKATNKENTKK"
     gene            50462..51136
                     /locus_tag="KRH23_001061"
     CDS             50462..51136
                     /locus_tag="KRH23_001061"
                     /EC_number="2.1.-.-"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0008171 - O-methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HHS5224350.1"
                     /translation="MSNIVNDLVEDYIRVTLKEKEGFLKDLEIYAEENSVPIIHKEVS
                     DLLKVLLKVQKPKRILEVGCAIGYSSIFFATIIGKDADIITVERNEKMIEKAKENIKL
                     AGFDNNITILEGDAEEKLSQVQGEFDLIFIDAAKGQYKLFFDLVIDKLKDGGLLVSDN
                     ILYKGMVAHDDFVVRRKKTIVKRMRNYLDYICNCDYLSTSLVPIGDGVALSYKESKRG
                     DVDGIK"
     gene            51123..52370
                     /locus_tag="KRH23_001062"
     CDS             51123..52370
                     /locus_tag="KRH23_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase U32 family protein"
                     /protein_id="HHS5224351.1"
                     /translation="MELNKVELLAPAGDLERLKIAITYGADAVYIGGEIFGMRSAAKN
                     FSKEDMAEGVAFAHERGKKVFVTVNIIPHNEDFLQLEDYLLELEEIGIDAVIIADPGV
                     LSVIKKVIPNMEIHLSTQANTTNYLSANFWYEHGIKRVVVARELSFDEISEIRAKTPL
                     DMDIEAFMHGAMCISYSGRCLISNYMTGRDANKGSCAQSCRWQYHLVEEKRPGEYFPI
                     YEDERGTFFFNSKDLCMIEYIPELIKSGITSLKIEGRMKTAYYVATVVRAYRMAIDEF
                     YRDPENWKFNPMWMEELKKGSHRHFTSGFYLNKPTTEDQNYQSASYVRNYDFIGIVRE
                     TEDEDGLIVVEQRNKMCVGDEIEVMGPYKETMFTKIEEMYNEEGEAIESAPHPRQIVK
                     LKLSVKVGKDYMLRKVIEEKVEE"
     gene            52442..54106
                     /locus_tag="KRH23_001063"
     CDS             52442..54106
                     /locus_tag="KRH23_001063"
                     /EC_number="3.4.16.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA];
                     GO_function: GO:0008955 - peptidoglycan
                     glycosyltransferase activity [Evidence IEA];
                     GO_function: GO:0009002 - serine-type D-Ala-D-Ala
                     carboxypeptidase activity [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan D,D-transpeptidase FtsI family
                     protein"
                     /protein_id="HHS5224352.1"
                     /translation="MSKKKTPFLKKVGKRSWCIFTIILIIYSVLIYRLVDIQVLKGDK
                     YKQSVESQSVEKVELNSGRGIIYDRNNKKLTDTSKSQVLIVEKEKLNNNYKILELIKK
                     ATKMNDLDIYKAVQEQLTRPIIQIQTKNIDKSMKKELEKNGIMVEEKTMRYAKDGLLS
                     HTIGYIKEDDKSGQSGIEKSMDSVLRNSNEKYISAFKAGDAGNEKSLNILKGSVKTVD
                     NKDKDRHLKTTIDYNIQKKLEQILNKEENPTAAIISEASTGEILAMCSRPNFDQNDIS
                     KSLKGKNGEFENRVIKATYPPGSVFKMVVLFSALENGVIDENYTYNCTGKTKVGNTNE
                     ILRCNKRDGHGFQNLRQAFSNSCNPAFLDIAMKLGKEKILKSAEKLHLFEKVDIGLDE
                     EKIREAPKNISIRNLAIGQENIEFTPLQINQMTQIIANNGTFKPLYLYKSLVDNNMNT
                     IKTYKSSKKEELISPYVCTQVKEYMKSVSRTGTAKDLKDIEGGCGVKTGTAQSSLNKK
                     AIDHGWITGFYPEERPKYVITVLVEGTQKGNKSATPIFKEICESIK"
     gene            complement(54203..54487)
                     /locus_tag="KRH23_001064"
     CDS             complement(54203..54487)
                     /locus_tag="KRH23_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012063608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HHS5224353.1"
                     /translation="MCNEISLLDILGTEANYVLDEVELKVQVGKLYEQLNKILTPRER
                     EIVQLRYGLTPYGYKTQREIAQKLDISRSYVSRIEKKALKKLEKELVQES"
     gene            complement(54510..56027)
                     /locus_tag="KRH23_001065"
     CDS             complement(54510..56027)
                     /locus_tag="KRH23_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HHS5224354.1"
                     /translation="MSVAIYLRKSRADEEAEKQGEFETLSRHKSTLLKLAKEQNLDVI
                     EIKEELVSGESIIHRPKMLELLKEVEENKYDAVLVMDLDRLGRGDMKDQGIILETFKE
                     SKTKIITPRKTYDLTDEFDEEYSEFEAFMARKELKLISRRMQRGRIKSVEEGNFIGTS
                     APFGYDAVTTGRKERILVPNKDADVVRTIFDLYINEDMGCSKISKYLNNLGIKTATGA
                     NWYNSAITNIIKNKVYCGYIQWQKKDYKKSKNPNKIKTVKLRPKDEWIEAKGKHEPLI
                     SEITWKKAQNILKKNGHVSYGNQIKNPLAGIVICKNCGRPLVYRPYADHDYIICYHPG
                     CNKSSRFEFIEAAILKSLEDTVKKYQLKASDIDLDKNNKDSNIEFQKRVLKGLETELK
                     ELGKQKNKLYDLLERGIYDEDTFIERSNNISSRTEEIKDSIKTVKNRLSTVKKDNSKI
                     IEDIKTVLSLYHDSDSLGKNKLLKSVINKAVYYKSKEQKLDSFELMVHLKLHEDQ"
     gene            complement(56152..56973)
                     /locus_tag="KRH23_001066"
     CDS             complement(56152..56973)
                     /locus_tag="KRH23_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HHS5224355.1"
                     /translation="MIISKKITAILVSFLIMISMVGCAPKESATEVAKKYLDSIEIKD
                     YEVAYNLLSKDSKESVSLEKFEEYQDTLFKLQTLKDYKLGEENKVEKYKYSNKEYTNL
                     VKIKETDTIKYITENKEDTANFDRYFIIEDNEYKLLWHKDFKRALSSNYVKIARSETE
                     KDKDKDYNKAAIDIKKAIEIDDKNPLAYYTQSYIYIELQRYDEALKSIDKYLEYLDKN
                     NEAYKIDASDAYNLRGVIFMSKSEFNKARESYNKALELNPDNEYAKTNLNDIKGL"
     gene            57164..58591
                     /locus_tag="KRH23_001067"
     CDS             57164..58591
                     /locus_tag="KRH23_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp26"
                     /protein_id="HHS5224356.1"
                     /translation="MKIKKLLTIGLSLSIFIASCPISANALDKIESIKGADKYETAGI
                     IADKQNYTTAILINADSTMADGLSASGLAGAINAPILLTKKNNIPNATLKRLEKAKKV
                     YIIGGENSIDKYTETVLKGKGIEIKRLQGSDRIKTSYNVAKEINSINKVNKVILTNAF
                     KGEPDAMSVAPVAVRDKAAIVLTDGKSVPFNTTGVESYVIGGTSSMNDKIVKDTNSTR
                     LGGTDRYDTNKKIINKFYSGVKEFYIASGTDLVYALVGSTVAKNNAIVLVDNDSNKSV
                     LKSTIKLTAIGNLSDSILQQCLNVTKNIGDSNTGREYTVEDAANAVKKLLGVKKFYYE
                     PNYSEDEDLIFLLDKNFDFSGKEYYVFAYIKQGAEGDLRYCVAKNDMSKVYTYDVNGN
                     MKVCNPDDYKNKGSITEEQAKQIALKECAKRHKVSINNLVVDMIDFRDDIYSGNVYAV
                     KINSKNSNGTFGWFFIDIETGKIYN"
     gene            58741..58893
                     /locus_tag="KRH23_001068"
     CDS             58741..58893
                     /locus_tag="KRH23_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA];
                     GO_function: GO:0090729 - toxin activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin"
                     /protein_id="HHS5224357.1"
                     /translation="MDNFLFNVLASLTASVVVYLISKLFKKAKSHSRTKSDLRVEFKF
                     IFKSKK"
     repeat_region   59547..59973
                     /inference="COORDINATES: alignment:CRISPRCasFinder:4.3.2"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=59547..59575
                     /rpt_unit_seq="gttttatattaactaagtggtatgtaaag"
     gene            complement(60260..60484)
                     /locus_tag="KRH23_001069"
     CDS             complement(60260..60484)
                     /locus_tag="KRH23_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHS5224358.1"
                     /translation="MDVNQRIKYTRENMNSSQKELLEKTNINTSVMNRIESGERPIRD
                     DGLIIFAKIFGLYTDYILGLSDTEKLNIGN"
     gene            61596..61814
                     /locus_tag="KRH23_001070"
     CDS             61596..61814
                     /locus_tag="KRH23_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224359.1"
                     /translation="MKILQQFKPYKYDKEKNIEYDEKIIANQNTEVYIVYPRISDEEN
                     RRRWEEFNEVAKEVAINIAMKKVETVES"
     gene            62459..62653
                     /locus_tag="KRH23_001071"
     CDS             62459..62653
                     /locus_tag="KRH23_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224360.1"
                     /translation="MKRRYKNVLIYINIRTIININCKIKFIELYLTFNELKNKLANNE
                     KTTVINENNKAFSGLVDFSN"
     gene            complement(63022..63405)
                     /locus_tag="KRH23_001072"
     CDS             complement(63022..63405)
                     /locus_tag="KRH23_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224361.1"
                     /translation="MRKKFFIGILIVLIISVIAILNIKNDKNVFIGESENWKAKFVTT
                     EGHSKLEIKYKNSKDVVEQKFNYSYQFIDGEDAVVVVKNEILEAGQEKAIKIQRPGLY
                     SNRESSYKLIISWNGNEETINLKKK"
     gene            63532..63876
                     /locus_tag="KRH23_001073"
     CDS             63532..63876
                     /locus_tag="KRH23_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224362.1"
                     /translation="MNYRLKKSVTTILSLLIMTILLPTNASASKVEDSSMKVMYSEKQ
                     VTDMDKLYDMAKNGITDVKSYNEKGIIKNARTGESIYVDYISTIQLLEVKQSKNLTSK
                     TYSKTVFLILIQ"
     gene            complement(65258..65575)
                     /locus_tag="KRH23_001074"
     CDS             complement(65258..65575)
                     /locus_tag="KRH23_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224363.1"
                     /translation="MNFRNIYLILMGLGIIILTTIISLIEIKIGFCNEKYFNKLESKY
                     GNIDRKRTIKLEVLYRYVTGFEYIAIGLFTKRLDITIIAIILVATITVILYYLVRKRY
                     ITI"
     gene            65738..65911
                     /locus_tag="KRH23_001075"
     CDS             65738..65911
                     /locus_tag="KRH23_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224364.1"
                     /translation="MNDATKVSIKNETNNIMNLCNLLSWNALLQNNKINAETIAKSRY
                     FIIILSPIDFYRL"
     gene            complement(66018..66200)
                     /locus_tag="KRH23_001076"
     CDS             complement(66018..66200)
                     /locus_tag="KRH23_001076"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224365.1"
                     /translation="MTLLELYYRKAEINKMVWARIGFNLYLSKGVALTLTDAGIGISG
                     LLAGAIPGIGKYLPLL"
     gene            66636..67025
                     /locus_tag="KRH23_001077"
     CDS             66636..67025
                     /locus_tag="KRH23_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HHS5224366.1"
                     /translation="MKINKLPHAELKLMKYIWGVDDVLASRDIIEDMKLKYDWKKSTT
                     LTFLKNLVDKGFLTTDKVDRCTHYTIAIKEKDYLKVETKSFFSFMHNNSFKSFISALH
                     DDEVLDSKSLDKLEEYFKNLKEGDIDD"
     gene            67350..67859
                     /gene="vanZ1"
                     /locus_tag="KRH23_001078"
     CDS             67350..67859
                     /gene="vanZ1"
                     /locus_tag="KRH23_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ1"
                     /protein_id="HHS5224367.1"
                     /translation="MKSRKHNITKGLFIVYIIILTWIILFKLQFDISSLETMNLRSIN
                     LVPFAGSLIINNRVDISEIILNVVIFVPFGIYVCMLKEEWSFIKKVIPIFITSLAFET
                     LQYIFALGASDITDLIGNTLGGIIGIAVFMLLSKIFKNNTIKIINVLALIVTIIVVLF
                     LGLVIFANL"
     gene            complement(67961..68155)
                     /locus_tag="KRH23_001079"
     CDS             complement(67961..68155)
                     /locus_tag="KRH23_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase"
                     /protein_id="HHS5224368.1"
                     /translation="MSVIVMCSRCGKEIDKYRNKYITYYEKNTNAEIKVCINCALDLL
                     EKTRENQELNIQEFQDTIIL"
     gene            complement(68671..69063)
                     /locus_tag="KRH23_001080"
     CDS             complement(68671..69063)
                     /locus_tag="KRH23_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HHS5224369.1"
                     /translation="MAALKSFEKPLTPEEEIEYLTKFKIENDKSAKDTLIERNMRLVA
                     YIAKKYNNSTEDQDDLISIGTIGLIKAIETYNIDKGTRLATYASRCIENEILMNIRSN
                     KKNKTQVSLQDPIGTDKEGNEINTTLYM"
     gene            69630..69992
                     /locus_tag="KRH23_001081"
     CDS             69630..69992
                     /locus_tag="KRH23_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224370.1"
                     /translation="MKIRKSGFISIECIISIAILYVAVYLVSTSLYNCYSFISRNISN
                     REMLSTAKKYIEDEKYRIQNSKYELIEDKIEKNYINGYEINSRIEQILDYYQCYEINI
                     EIKNEFKKLRFNSYVTRK"
     gene            69976..70686
                     /locus_tag="KRH23_001082"
     CDS             69976..70686
                     /locus_tag="KRH23_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224371.1"
                     /translation="MLLENKGSILIITLIIFSIISTVCIMCIGLIYTHNNMFELGYKD
                     IQLKEISLSGIEISVSNVLSCVEEAIDVSNNEDEFREYFLGNNMIECIKKIKDTSYSS
                     LEELSLKVENNTIYDRGDFFEFDIESNVREKEFLKAIKVRVKIKNPWTGIDIEDYMDK
                     SNNNKIDDKTFNNYKASENNEILNQFKNESENIRNQEVVEFTEEEYEEELKQNIIENI
                     KKNFNEKNLVQVYKYRGV"
     gene            70706..71125
                     /locus_tag="KRH23_001083"
     CDS             70706..71125
                     /locus_tag="KRH23_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224372.1"
                     /translation="MTVIELIVSISIILLIVTLSFPKDNLENHKINLFARQLCSDIRY
                     VRRINMFSNYNTYIYYINQGKHEGYVLRKDGKNIKSIMLPKNAKIARSIEIIKFKSDG
                     SPQKASTIEVYNNRLRKTITITPVSGRVLLKEGKYET"
     gene            71115..71639
                     /locus_tag="KRH23_001084"
     CDS             71115..71639
                     /locus_tag="KRH23_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224373.1"
                     /translation="MKHKYGYLLLESVVSLSSMVIIILVLYSIFLSTINLKLKVEDKI
                     ELQQQSLEIIKSMEGIISNSMGIMNVSNYEETFKKTTSIKCRYLDENNNEEGISNKEI
                     ILNERRNKLFVNSLNGESSQAGGYEIGDYVDEMYVSITNNGQYVNIKLKLSKRSQKYE
                     TDFKIKVWNFSESI"
     gene            71951..72508
                     /gene="efp"
                     /locus_tag="KRH23_001085"
     CDS             71951..72508
                     /gene="efp"
                     /locus_tag="KRH23_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HHS5224374.1"
                     /translation="MVSAGDFRKGVTFEKDGQPCLVVDFQHVKPGKGAAFVRTKYKNL
                     KTGAIREESFNPSEKFPKAVIDTRQMQYLYNDGELYYFMDQENFEQIPLNYEQVEDAI
                     KFLKENEVATIRFYQGQPFQVEAPNFAELEVTDTEPGIKGDTASNVTKAATVETGAVV
                     QVPLFINTGDKVKIDTRTGEYLSRV"
     gene            72600..73055
                     /locus_tag="KRH23_001086"
     CDS             72600..73055
                     /locus_tag="KRH23_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CD1247 N-terminal domain-containing protein"
                     /protein_id="HHS5224375.1"
                     /translation="MKHLYEEVAYLKGLAEGLEISAESKEGKMIHKIVDALEVFADAI
                     VTLDEEQEELQDFVESIDEDLADLEEDIADMEEDLYEEDDDEDDEDFSYIEMECPNCG
                     ELVEIDEDLLYDDEVDVVCPDCKAVILSSEDDCDDDCTCGGCSSCDDRE"
     gene            73218..73928
                     /gene="rnc"
                     /locus_tag="KRH23_001087"
     CDS             73218..73928
                     /gene="rnc"
                     /locus_tag="KRH23_001087"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004525 - ribonuclease III activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HHS5224376.1"
                     /translation="MKISKKLLDNIQRFENVINYKFKNKEYILEALTHSSYSNENKKY
                     NFNERLEFLGDSVLGIVISDYLFNEEANLPEGELTKLRANIVCEDSLSEVANDINLGI
                     HMLLGRGEEATGGRHRTSILADAFEAVIAAIYLDGGFESARQFILHHMENIIYDSRKG
                     NIFRDYKTHLQEVLQGNGENNIWYRLIEEKGPDHNKRFVMEVGINDDVLGIGEGKSKK
                     EAEQLAAKIALKKKLWEK"
     gene            73982..75052
                     /locus_tag="KRH23_001088"
     CDS             73982..75052
                     /locus_tag="KRH23_001088"
                     /EC_number="2.3.1.311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016407 - acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006448 - regulation of translational
                     elongation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongator complex protein 3"
                     /protein_id="HHS5224377.1"
                     /translation="MKKRIIPIFVPHKGCPHDCIFCNQKKITGVSTDVTSEDARNIIE
                     ECLETIDKDADVEIAFFGGSFTAIDINIQKSLLSVAKEYVEKGLVKDIRMSTRPDCID
                     EDILSMLKEYKTSIIELGVQSLDEKVLLDSIRGHQSEIVYKSSKMIKNSGIKLGLQMM
                     IGLPADTEEKCIFTAKKFVELKPDCVRVYPTLVVKDTGLEKLMEQNKYNPFTLEESVN
                     IVKKVLVLFYVNNINVIRVGLQATDDIQIGKAVLAGPYHPAFRELVEADMIKDYLEFV
                     IFQNKNIKQMLVKSNKKNISKIIGNKKTNVKYMEEKFGVLLKTQESDLDINQLEIVLD
                     GKSLISANMRDIHRKLYDIYDL"
     gene            75080..78634
                     /gene="smc"
                     /locus_tag="KRH23_001089"
     CDS             75080..78634
                     /gene="smc"
                     /locus_tag="KRH23_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HHS5224378.1"
                     /translation="MYLKRLELKGFKSFPVKTDIIFKEGITAIVGPNGSGKSNISDAV
                     RWVLGEQSIKSLRGDKLEDVIFAGTDTKKPMNYCEVALTIDNSENQLELDFTEVTIRR
                     RAYRNGESEFFLNNKSCRLKDIKEVFLDTGIGKDGYSIIEQGKVDEILSNNPLSRRKV
                     FDEACGISKYRYKKQEAERNLSNTKENLERIDDVYIEIENQLKPLFNQQTKAKKYLEI
                     SEKLKTLEVNSFIREIEGIEKELSEVNEHRKVIEKELNEKEEQKNVVEKKQEDINKEV
                     EVLQDVIEKSVDYINSIKGVISKKESQINLIKERIRNFTNEISRKNLEIKDIKEKLNE
                     NKQYIKELESNKLSGSEELSTLQENIKVLESSKDKQKIKLESLNNEIELLKESIIDIL
                     NKKQEFSNKLSTLNANKENMNIRDENINSEITELNKNIEIKSSELDTINKEFNMQNEN
                     LKNVNNRHKELSINLQDSISEHNKLEDEIQKSKYNLNGYNSKLNVYIDMENHYEGFNR
                     GVKEVLKNKNLKGVHGALGQIINVPEKYEKSIEAALGAYMQNIITDNEFSAKSAINYL
                     KQNNLGRVTFLPLNIIKSNKISLGNLKANTKFIGIASDLITFDEKYRNIIENILGRTI
                     LINNIDEGIKFAKETGHRFKIVTLDGEILNPGGSLTGGSLKTNGNILSRKRYINEYTE
                     KISNIKNEISHLELKRESLDKDVKNIKNEIDSHESKIKDLEKSIIIKSTSIKNVESEI
                     ESLKGSITKLENEKNDLNSNLNYTLEKSDDVRKDMEELDDLYNKNKEKIDALNEEIKR
                     YNDLYDKEKSEFDELNLSLVKKTEVYNSIVRDIKRISGENCELEEKNKQLEESLNYEE
                     HEIIKLQDSILTEEKEKENLTKQLGDSNRNLETRKIAKDDLKNSFDEINKELKTIDRQ
                     HIELKESLFKVGGRLERLKTSQDTYINKLFEQYDMTLVQALEIKDEDLDIDRKFLESL
                     KREIRSLGNINIDSIKEYEEIKERYDFYSEQKQDLEESMEEIEKLIHTLEENMKSEFE
                     IKFEEISKNFKYVYKRLFGGGCGELTILDKENLLESDILITAQPPGKKMKNLNLLSGG
                     EKALTAISILFAILITKPTPFCILDEIEAPLDDANIFRFGEFLKDLSKETQFISVTHR
                     RGTMEAADYIYGVTMQEKAISKVISLKLKEAQEITDII"
     gene            78661..79941
                     /gene="ftsY"
                     /locus_tag="KRH23_001090"
     CDS             78661..79941
                     /gene="ftsY"
                     /locus_tag="KRH23_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005047 - signal recognition particle
                     binding [Evidence IEA];
                     GO_process: GO:0006614 - SRP-dependent cotranslational
                     protein targeting to membrane [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HHS5224379.1"
                     /translation="MLKKLFGFGKDKEKEIEKKDAEEEIEVEDSVDNLENLEETIFSG
                     LEEEVIDKVEDIEEKNEESVNNEGTEEIENFEKIEVEMDSNGKEVENISNNDSQEEII
                     EELENYDEIESKEIEDKEDKKVNLFERLKQGLTKAKQGITDRIDEVLKSYTKIDEELL
                     EDLEEILITADVGVNTTMDIIERLRDKIKQKGITEPIKVREELKSIVEDILTNENSTL
                     DIEPAPCIILMVGVNGVGKTTTIGKLANRYKKDGKKVLLAAADTFRAAATEQLEIWAN
                     RTNVDIIKHQEGADPGAVVFDAIKAAKARKTDVLICDTAGRLHNKANLMNELGKVFKI
                     VDREFPEAKREVLLVVDATTGQNAVVQAKTFKEVADITGIVLTKLDGTAKGGVVLAVK
                     SEVDVPVKLIGVGESVEDLQDFNAKSFSDALFGN"
     gene            80044..80412
                     /gene="ylxM"
                     /locus_tag="KRH23_001091"
     CDS             80044..80412
                     /gene="ylxM"
                     /locus_tag="KRH23_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0048500 - signal recognition particle
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YlxM family DNA-binding protein"
                     /protein_id="HHS5224380.1"
                     /translation="MNIEKMVEIGLLFEQYKELLTDKQKEIVALYYEEDYSLGEISEN
                     LNVSRQGVYDTLKRSEKILRDYEEKLHLVSKIQEQEKNIKIIKDKIIDIKEDLLHNRD
                     CANLIPKLENIEDVCREMIK"
     gene            80409..81761
                     /gene="ffh"
                     /locus_tag="KRH23_001092"
     CDS             80409..81761
                     /gene="ffh"
                     /locus_tag="KRH23_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0048501 - signal recognition particle,
                     plasma membrane targeting [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005048 - signal sequence binding
                     [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HHS5224381.1"
                     /translation="MIFEGLSDKLQGAFSKLKSKGKLTEVDVKNAMREVKLALLEADV
                     NFKVVKDFIKKVQERCVGQEVMQSLTPAQHVIKIVNEELTSLMGDVQSKVMISSKPPT
                     ILMMVGLQGAGKTTTAGKLGGYFKKQGKKPLLVACDIYRPAAIKQLQVVGEKLDIPVF
                     NMGDKENPVNIAKAGLSHAIKNANDLVIIDTAGRLHIDEVLMDELKSIKSEVKPHEIL
                     LVVDSMTGQDAVNVAESFNEALGVDGVVLTKLDGDTRGGAALSIRAVTQKPIKFMGMG
                     EKLDDIEPFHPDRMASRILGMGDVLSLIEKAQENIDLEKAKELEQKIKKQELDFEDFL
                     QQMEQIQNMGPLDKILGMIPGMGNVKDQLGDVDLNGKEMKRTKAIIQSMTTYERRNPG
                     VLNASRKKRIAKGSGTSVQDVNRLIKQLNEMKKMMKMFAGSQKSMKKRGGLGGLPFFK
                     "
     gene            81799..82071
                     /gene="rpsP"
                     /locus_tag="KRH23_001093"
     CDS             81799..82071
                     /gene="rpsP"
                     /locus_tag="KRH23_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HHS5224382.1"
                     /translation="MAVKIRLKRMGANKKPFYRIVVADSRAPRDGKFIEEIGYYNPIS
                     EPKQVRINDEKAIKWLATGAQPTEVVKKLLVKNGVIEKFEASKQAK"
     gene            82136..82363
                     /locus_tag="KRH23_001094"
     CDS             82136..82363
                     /locus_tag="KRH23_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HHS5224383.1"
                     /translation="MKELVVDIAKALVDNPDSVVVEEFEDNDGIVLKLTVAQEDMGKV
                     IGKQGRIAKAIRTVVRSVANRENIKVSLEIV"
     gene            82471..82986
                     /gene="rimM"
                     /locus_tag="KRH23_001095"
     CDS             82471..82986
                     /gene="rimM"
                     /locus_tag="KRH23_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438220.1"
                     /note="Essential for efficient processing of 16S rRNA;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HHS5224384.1"
                     /translation="MKEKLTHFKVGQIVNTQGLKGEVRVYPLTDDIERFDELKDFYLG
                     KDLNNKLAVEKVRYKGSMVIMKIKGIDSIEKAEKLKNKFMYVAREDSRELEEGEFFIA
                     DMIGMEVLTVDGKYVGILEDVLQYSANDVYVVKGEEDKEFMIPAIKKFVPTIDIDERK
                     MIIDPIKGMID"
     gene            82995..83690
                     /gene="trmD"
                     /locus_tag="KRH23_001096"
     CDS             82995..83690
                     /gene="trmD"
                     /locus_tag="KRH23_001096"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052906 - tRNA
                     (guanine(37)-N1)-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0030488 - tRNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HHS5224385.1"
                     /translation="MRFHIMTLFPEIFNSYMDESIMKRAVEKGIIEVHIYNIRDFSNN
                     KHKKVDDYPFGGGAGMVMTPQPIYDTYKHIITTHNINNPSVIYLTPKGKVYNQSMAKQ
                     MSLKEDIILLCGHYEGIDERIIDLIVTDEISIGDYVLTGGELPALIMIDSISRLIPGV
                     LNQEESFEEESFKDNLLEYPHYTRPRDFEGLKVPEVLLSGNHKKIDEWRREESIRITK
                     ERRFDLYKKSNEK"
     gene            83875..84225
                     /gene="rplS"
                     /locus_tag="KRH23_001097"
     CDS             83875..84225
                     /gene="rplS"
                     /locus_tag="KRH23_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000311 - plastid large ribosomal subunit
                     [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HHS5224386.1"
                     /translation="MNEMLRAIEQEQLKNEVPNFGPGDTVKVHVRIIEGKRERIQVFE
                     GVVLKRQGGGARETFTVRKMSFNVGVERTFPVHSPKIEKIEVTRKGKVRRAKLNYLRG
                     RVGKAAKIKEARNK"
     gene            84546..85442
                     /gene="ylqF"
                     /locus_tag="KRH23_001098"
     CDS             84546..85442
                     /gene="ylqF"
                     /locus_tag="KRH23_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HHS5224387.1"
                     /translation="MSNEYEEYLMNDNLHINWYPGHMKKTKELVKNNLKLIDVVIELL
                     DARIPFSSKNPDIDRLVGDKPRVVVLNKSDMADRDKLNQWIEYYKKINIKAIPVDTIK
                     GVGINKIIEECKNVTREKMSSLKDKGRKERAIRIMIVGVPNVGKSSLINKLTGRKSTQ
                     TGDKPGVTKGKQWVRLKGNLELLDTPGILWPKFEDQEVALNLAFSRAIKDEILDTETL
                     ALRLIEKLMKIEPEKLKARYKLDCLGETPIETMDMIGHKRGFITGKKELDYTRIATTV
                     LNEFRDGKIGNITLEVPENVKR"
BASE COUNT        34790 a         8674 c        15157 g        27041 t
ORIGIN      
        1 ctacattaag ttaacttgtt aatatattat tagtgaaata cacaatttac catactagaa
       61 atatgatata atataaaaaa aaagtatata cttttatatt aaaaggtgat atattattta
      121 tgaaaatcgt ttaatgtata caataatata tctataacaa aataataaaa gatagagttt
      181 tatttagaca tttattacaa atcaaaattt attacatatt atttataaaa aaatctaagg
      241 aggaaataat aatgaaaata ttagtattaa actgtgggag ttcttcatta aaatatcaat
      301 taatagatat gaataatgaa gaagttttat gtataggatt ggttgaaaga ataggaatag
      361 aaggttctat attaaaacat gaaaaagcag gtagagatga taaatacgtt gttgaacaac
      421 caatgaagga ccacaaagat gcaatagcat tagttttaga agctgttgct catccagaat
      481 ttggtgcagt taaagaaatg aaagaaatag atgcagtagg acatagagtt gtacatgctg
      541 gagaaaaatt tgcaacttca gtagtaataa ctccagaagt agaagaagct ttaaaagaat
      601 gtatagattt agctccactt cataatccag caaacataat gggaatagat gcttgtaaag
      661 ctatacttcc agatgtacca atggtaggtg tatttgatac tgctttccat caaacaatgc
      721 ctaaatcttc atacttatat ggtttacctc atgagctata tactaaatat ggggtaagaa
      781 gatatggatt ccacggaact tctcataatt atgtatctca aagagcagca gagatattag
      841 gaaaagatat aaaagattta aaaatagtaa cttgtcactt aggaaatggt gcttctatag
      901 ctgctgttga tggtggaaaa tgtgtagata catctatggg attcactcca ttagaaggat
      961 taataatggg aactagatgt ggagatatag acccagctat attaccattc ttaatgagaa
     1021 aagaaggttt agatgctgat ggattggata aattaatgaa taaagaatct ggagtatatg
     1081 gaatgactgg aatttctagt gacttcagag atatagaaga tgcagctaaa aatggagacg
     1141 aaagagctca agctacatta gaagcgtatg ttaaaaaagt acaaaaatat ataggcgctt
     1201 atgctgctga aatgaatgga ttggatgttg tagtatttac tgcaggcgtt ggtgaaaatg
     1261 gaaaggctat aagagcagat attgcttcta acatggagtt tttaggaatg aaattagata
     1321 aagaagctaa tgatgttaga ggaaaagaaa cagtaatatc tactgctgat tctaaagtaa
     1381 aaatgctttt aataccaact aatgaagaat taatgatagc tagagataca ttaagattgg
     1441 taaaataatt aaattaaacc tatgcctatc aagtaaaaat acttgacaaa caaatgctag
     1501 atttgtataa taaatttggt gatatgttga ggtgaactta atgaaagtta gcatagaaaa
     1561 aataaataga aaagaaactg acaaaataga cttgaatttt tgtgaaaaaa ttgatactat
     1621 tagttattgt gatgagattt acaaattagt atcacctgta aatttaaaag ggaaagtgtc
     1681 aaagactaat aaaggtttgt atctagatat agatgtcaat tttacaattg ttgacaattg
     1741 ttcaagatgt cttaaagaag tagaaatacc actagagtat tctatacaag gttttttagt
     1801 aaaagaagaa gattatgatg aagatgagtt tgaggaattt gatcctttta tattcgatgg
     1861 tgaagaaatc gaccttattg atataataga acagacatta gattttaatg tacctcataa
     1921 agttctttgt agtgaaaact gtaaaggtct ttgtcaagta tgcggggcaa acttaaatga
     1981 agaagagtgt tcttgcagtg aaattacaaa cgatgaggaa tacatagatc ctcgttttgc
     2041 taaattaaaa gatttattta attaaatttt gactaaggag gtggcgtaaa tggcagtacc
     2101 aaagcgtaaa acgtctaaat caaacacaaa aatgagaaga gcagctaact caaagatgga
     2161 agcaacagga tttgtaagtt gcccacaatg tcatgagcca aaattaccac atagagtgtg
     2221 tccagactgt ggatattata aaggtaaaga agttgtgtct aagtaatagc ttctaaaaag
     2281 catgtagagt atactctaca tgtttttttt gtacatataa aaaaataaga tgatttacta
     2341 gagaaaataa gtggatttta tgcatattaa aaaatagaaa aataataata taagtattga
     2401 aaatttttgt gtgttactat atactactat tagtagctgg tactaattac agctataaaa
     2461 tttggaggga acatgaaaaa gaaaagtaaa gcccaaagac aaaaagagct tatagatatg
     2521 ctaaagacag atccttttta tactgatgaa gaattatcaa gtctgtttga tgtaagtata
     2581 cagaccataa gattagatag aatgagtcta aacataccag agctaagaga aagagtcaaa
     2641 tcaatagcag aaactcagag ttcaaaagta aagactttag gagtaaagga aattacagga
     2701 gaaatcattg atttatctgt agggcgatta ggtatatcta tgttagaagt tacacaggac
     2761 atgatttact ctaagactaa tactttaaaa gatacgtata ttttttctct agcagattca
     2821 ttggcaatgg ctataataga tgcacctaag gttattatga gagttgcaaa tgtaaaaagt
     2881 tttaagttga tagaacaaca agataggctt atagcaaaag cagaagtgta tagaaatata
     2941 gataaaaagc attatgtaaa agttgttatc aacaataaag cccaagagca aatatttaga
     3001 ggaaagttta tctttgaaga attagattag gagggaaatt atgaaaatag taattgatgg
     3061 aatgggtgga gataatgcac ctaaatctaa tgtagaaggc gcagtaaatg ctataaaaga
     3121 atatcaggtt gatttaataa tcacaggaga taaagattta cttgaaaagg aattttcaaa
     3181 ttatgaattt gatagaaata aattagagat agttcatact actgagatta tagaaaacga
     3241 agataaacca gtaaaggcta taagaagtaa aaaagattca tctatggtag tagcattaaa
     3301 tcttgtaaaa gaaggaaagg cagatgctat aatatcagct ggaaatacag gagccttact
     3361 tgctggtgga ttatttgttg ttggtagaat aaaaggaatc gatagacctt gcttatgttc
     3421 agcaatacca aatgtaaagc gaggaatgac acttatagca gactgtggcg caaatgcaga
     3481 ttgtaaacct aagaatctag ttgaatttgc agctatgagt aatatttatt caagaaaagt
     3541 tttaggtctt gaaaatccta aggtagcatt agcaaatgtt ggactagaag aaggcaaagg
     3601 caatgattta gtcaaaaggt catatgaaga aattaaaaaa ttagatttaa attttatagg
     3661 gaatgtagaa gctagagaag ttataaatgc atacacagat ataatcatat gtgatggatt
     3721 tacaggtaat atattactta aatctgctga aggtgtagca ctttcagtta tgagtcttat
     3781 aaaggaaact tttatggcca gtacaaaaag taaaatagga gcattactta taaaggatga
     3841 tttaagaaaa ttaaaaagtt ttatagatta ttctgagtat gggggagctc cacttttagg
     3901 tctaaatgga ggagttataa aagctcatgg tagttctgat gctaaagcta taaaaaatgc
     3961 tataaatcaa ggaataaaat tttcaaaggg aaaagtcgtt gaagatatta accaatttat
     4021 aagcaaatac aatgaagaaa ataaaaataa cgaagatgaa taaactcgtt ttggaggttt
     4081 aatatataat gaatacaaag gctggaatat taggagtagg aagttatcta cctgagcaat
     4141 catatgataa ttttcacttc gaaaaaataa tggatacatc agatgagtgg ataagtacta
     4201 gaactggtat taaggaaaga agatttgcca aagagtctga agcaacttct gacttagcat
     4261 ctaaagctgc cttaaaagct atagaatgtg caaagttaaa cgtagaggat atagagctga
     4321 ttatattagc tacaattact cctgatatgt ctttgccttc aactgcatgt atagtacaag
     4381 atgcaatagg agcagtaaat gctactgcat ttgatatatc agcagcttgt tctggatttg
     4441 tatatggagt aactattgca aagcaatttg tggaaacagg ttgctataaa aatgtgcttg
     4501 taataggagc agaaacttgt tctaagtttt taaattatga tgatagaaca acagcagtat
     4561 tgtttggaga tggagctgga gcagctgtta ttggccctgt aaatgagggt ggaatactgt
     4621 ctacacatat gggctctgat ggtaaaggaa aagattgttt aaaagtacct gctggaggtt
     4681 caagacttaa ggcaagtaaa gagactgtag aagctaatct acatacaata gaaatggcag
     4741 gtagtgatgt gtttaaattt gcagttagaa agatggcaga aacttcttta agagctcttg
     4801 aaaaagcaaa tctaaataca actgatatag actacttagt gccacatcaa gctaatataa
     4861 gaatcataca agcttcttct aagagattag agcttgatat gaaaaaagtt tatgtaaata
     4921 tagacaaata tggaaatatg tctgctgcat ctataccagt agcattagat gaagcttata
     4981 gagaaggtaa aattaaaaag ggtgataatg tagttttagt tggctttggt ggaggtctaa
     5041 cttggggggc ttcagttgtc aagtggactt tatagtataa aatatctaaa atgatttaat
     5101 taacaaaatt aaacttatac acaaaataaa gttgattaat aataaaaagt ttacttttat
     5161 gatttcaagt gaaggagaat tgtatgaata aaatttgcaa aatattaaat ataaaatacc
     5221 cagttatcca agggggaatg gcatgggtag ctactgcatc attagcaagt gctgtatcta
     5281 atgcaggagg acttggcata atagcagcag gaaacgcacc aaaagaagct ataaagaaag
     5341 aaattgttga gtgtaaaaaa ttaacagata aaccttttgg agtaaatgta atgcttatgt
     5401 cgccatttgt tgatgatata attgatttga ttatagaaga aaaagttcaa gttattacta
     5461 ctggtgctgg aaatcctgca aagtatatgg atagattaaa ggaagctgga acaaaggtta
     5521 ttcctgtagt acctacaata gctttggcac aaagaatgga aaagctagga gctacagcag
     5581 taatagcaga aggtactgaa ggtggaggac atataggaga acttactact atggtcttag
     5641 ttccacaagt tgctgatgct gtaaacatac ctgtaatagc tgctggagga attgtagatg
     5701 gtagaggaat tgcagcatca tttgcattag gtgccagtgc agttcaagta ggaactagat
     5761 ttatttgtag tgaagagtgt tctgtccatt caaactataa aaacttagta ctaaaagcaa
     5821 aagatagaga tgcaattgta acaggaagaa gtactggtca tccagtaaga acattaaaaa
     5881 ataaactatc aaaagaattt ttaaagatgg aacaaaatgg agctactcct gaagaactgg
     5941 ataaaaaagg tacaggagct ttaagatttg caacagtaga tggagacata gaaaaaggtt
     6001 catttatggc aggtcaaagt gctgctatgg taaaagaaat aacaccttgt aaggaaatta
     6061 tagaggctat ggtaaatcaa gcaagagaga ttatgccagc aatagaactg taaatcagga
     6121 ggagcaagat gggaaaagtt gcactagtat tccctggtca aggagctcaa tatgtaggta
     6181 tggccaagga tttatatgaa aataatactg ttgctaaaag tgtaatagat gaggctagtg
     6241 atgccttaaa tatggattta aaaaacctta tgtttaatgg aaatgaagaa gaactttcta
     6301 aaactgaaaa cactcaacct gctatggtta cacatagtgt agcagtatta aaagcggtac
     6361 aagctcaaat agatttaaaa tataatgcat gcttaggatt atccttagga gagtatagtg
     6421 cgttggttgc agcagatgca attgacttta aagatgctgt atgtttagtt aaaaaaagag
     6481 gtaagtttat gcaggaaaca gttccagcag gtgttggagc tatggcagca attttaggtt
     6541 tagatagaaa tgtacttgaa aatgtggtta aagatataca aggaggtatt gtagaagtag
     6601 caaattacaa ttctcctgga caaatagtta tatctggtga aaatgaaaag atagaagaag
     6661 caatggtaaa atgcaaagaa gcaggagcaa aaagggcagt taaattaaat gtaagtggac
     6721 cttttcactc atcaatgtta aaagaagctg gtgtaaaatt ggccagtgaa ttagaaaaag
     6781 ttaacataac taaacctaaa gttgatgtgg tggcaaatgt aaatgcagat tactataaaa
     6841 acgaaggtaa agacctgctt ataaaacaag taagttcatc tgttctttgg gaagattcta
     6901 tagaaagact tttaaatgat ggatatgata cttttataga aatgggacct ggaaaaactt
     6961 taaaagcatt tattaagaag atagcttcca ataaaaaagc aaatgtcaat atttataata
     7021 tagatggtat agattctctt aatgaatttg tacaaaatta tagaaatgga gagatataat
     7081 gataaatctt acaggacaag tagcagttgt tactggtggc tctaggggta taggaaaaga
     7141 aatagcaaaa aaactagcat cttttggagc tgatgtagta atcaattata cttctaaaga
     7201 agatgaagca ctaaaaacta aaaatgaaat agaaagtatg ggggtaaagt gtacctctat
     7261 aaaatgtgat gtgtctaaat ttgatgaagt gaatcaaatg atagattctg ttgtaagcga
     7321 atttggaaaa attgatatat tggttaataa tgcaggcata actaaagatg gtctgcttat
     7381 gagaatgaaa gaagaagatt ttgatagagt tatagatata aacttaaaag gtgtctttaa
     7441 ttgtacaaaa gcagttacta aacctatgat gaaaaagaag tatggaagaa taataaatat
     7501 gacttcagta gttggaatta tgggtaatgc agggcaaact aattattgtg catcaaaagc
     7561 aggtgtaatt ggatttacaa aagcttctgc aagagagtta gcatcaagaa acataaatat
     7621 aaatgcagta gcacctggat ttatagaaac agatatgact aaagtactaa gtgatgatgt
     7681 aaaagaatca acactagcaa acataccaaa gaaatcttat ggtaaaccag aagatgtagc
     7741 caatgccgta gcatttttag ttagtgacat gtcaagttat ataacaggac aagtaataaa
     7801 tgtagatggt ggaatggtaa tgcaataata atttaaaaag tagagaaatc tattaaaata
     7861 aaaaatttta ggaggtacac aatgtttaat aaagttgtag aaataataat agagcaatta
     7921 ggagtagaag ataaagaaat aactatggaa acatcattaa tgaaggattt agaagcagat
     7981 tcattagatg cagtagaaat aataatggca cttgaagatg aatttggtat agaaatacca
     8041 gatacagaag cagaaaactt caaatctata ggagatatag ttaagtatat agaagctaat
     8101 aaatagtcga gctttaaaaa agtggaggta tccgatgaat aaaagagtag taataacagg
     8161 acttggatgt gttacgccgt tgggaacagg aaaagaagag ttctggagta atataaaatc
     8221 tggagtatct ggtatagata aaataactaa ttttgatgct agcacatatc aaactcagat
     8281 agcaggagaa gttaagaatt ttcatccaga agaatatata agtaaaaaag aattgaagag
     8341 attagataaa tttgctcaat ttgcaatagt atctgctaaa ttagcagttg aagatgcaaa
     8401 tcttgattta gataaagttg atagagaacg ttttggtgtt ataataggtt ctggaatagg
     8461 tggagttgaa gctatagaaa ctcaacataa aattcttttg gaaaaaggaa ataaaagagt
     8521 aagttcactt tttgtaccta tgatgatagg aaatatggca gctggtcaag tttcaatatt
     8581 tttaggagca aaagggccta acactaatgt atgtacagct tgtgcatcag gaactcattc
     8641 aataggtgat gcttttaagg taattcaaag aggtgatgca gacattatgg tagcaggggg
     8701 ttctgaagct gctgtaacag gtcttgcttt tgctggattc tgtaacatga aggctatgtc
     8761 aactagaaat gatgacccta aaactgcatc aagaccattt gataaagaca gagatggttt
     8821 tgtaatggga gaaggagcag gtattgttat cttagaagac ttagaacatg ctttagcaag
     8881 aggtgctaaa atatatgcag aagtagttgg atatggttta actgctgatg cataccatat
     8941 gacaactcca gctgaaaatg gagagggagc agctaggtct atgaatatgg ctttgaaaga
     9001 tggaaatgtt ccattagaag aagtagatta tataaatgct catggaactt caacttatta
     9061 caatgattta tatgaaacta tggctataaa aactgtattt ggagaaaagg catatgactt
     9121 atgtgtgtca tcaacaaaat ctatgactgg tcacttatta ggagcatcag gtgctataga
     9181 ggctgttgtt tgtgctatga gtatagaaga tagttttgtg cctccaacta taaacataca
     9241 agaagttggt gaagatttgg atttagatta tgttccaaat caaggtaaag aaaaaaatat
     9301 tagatatgca ctatcaaatt ctttaggatt tggtgggcat aatgctacaa tagtactaaa
     9361 aaaatatgta taaataaata ttaaatataa aactaaaaaa caagcacttg ttttaactgt
     9421 ataaatttat attagcttaa atttaaagtc tcctaaatta ttttaggaga cttttttatt
     9481 aagatttaag tctaggatat gttgtaaatc attttgatat attgtattat taattattaa
     9541 gaggttattt atatatgcaa gttttcattc tacaatatac aaaaggagga ctaaaatttt
     9601 gaattttaga ctaccaaaga aaaggttacc caaaaagata atttttatat gtataatact
     9661 tattagtatt attttgttta taaagtatga ccaaaatgga ttgaaagaaa gagaaattat
     9721 aaataaggga aaatatatgt ctgaaagcct tgtggcagat aaggagtatg atgaagcaaa
     9781 aaaagtggtt aagacttctt ttgaatctat tccagaaaaa aaatacaata aagtatataa
     9841 tgaagtttgg gatatgttaa agactatttc atatgttcca gatggaacga agatagtcat
     9901 tgattcttta gaaaagatga gagaatcaga tgtgaaatta tctgatgaat gtagatttaa
     9961 tatagaaaaa agattagcat cagtgtatat aatggataat aattattcta aggcagtaga
    10021 tttaactgta aagtctataa agttggctga gaaattgggg aataattatg aaaaagcaag
    10081 actagatgtt gatttggcga gcatattttt aaagataggt ggctatgaaa caggagagaa
    10141 attaataaag gattctttta aaatagatat tgatgaaggt gaaaaaaatg gaatggttag
    10201 attatatgct attataaatc tagcagaaat atatgtagaa gagggagaat atgataaagc
    10261 tattgaaata agtagcagga taaaagatta taaaaagttt gtaaatacgg ataattacaa
    10321 tgattttgat ataatggcct ctataatgca gtcaaatgcg tatgtgggca aaaataatat
    10381 acaaaaggca aagacttttt tagaaaaagc tgattatctt ataaaatcag atagaacagt
    10441 ttatatatta gataaagata tgtactatta tatggcaatg ggaaacttag aatataaaag
    10501 cgaaaattat aattctgcaa tagataatta taaaaaaagt ttagagatat ctaccaaaag
    10561 aaagttaact caggagaaaa taaaaaattt aaataagata ttaaatatat atgaaaaaca
    10621 aggaaatata gaatctttaa atgagtatca aaagatgtta ataaatgaat ataaagagaa
    10681 caaaagtata agagattcag agactagttt ctatataatt gataaagtat caaacgaaag
    10741 taagctattt gaaaaaacta aaaaagaaat aaaatattat aaaatattat ttacagtaat
    10801 tttaattgct atattagggt ctactttttt atacaaccga ttgaagtatt ttaaagcaca
    10861 aaatttacat gatggtctta caaatgttta taatagaaaa agttttgata ttatgtatga
    10921 aaagtacaga gataaagatg ataattttgc acttgtgatg atagatattg ataatttcaa
    10981 gctcataaat gataattatg gacataaatt tggtgacact gttataaagg gaataacaaa
    11041 taccatttgt gttatgttag aacaagatga taaagtcttt aggtacggag gagaagaatt
    11101 ttctgtatta ataagaaata aatctggtga ggaagtagca gatataattg acagtataag
    11161 ggttgcaatt gcaaataaaa aatggaatga tgatgtgact gtgactataa gtgcaggtgt
    11221 agctcatgtt tcagatagca aagatgtact agaagaagct gataaaaatt tatataaagc
    11281 aaaacaactt ggtagaaata aagtagtata taagtaatta tatactatat aaataagagg
    11341 tataaatatg aaacaatcaa tagctatagt aactgataaa ataactaaac tatcatcttt
    11401 cttagaagaa aatatacgtt tggttttagg taattatatt gatataaacc actattatct
    11461 ggaagtttta aaagagaatg ataaaataca aggtaatttt gtactagtaa tgaatgatga
    11521 tagattaaac agtatgagaa agcatttagt acaagatagt aagattatag tgataaggag
    11581 aacacttaaa gaaaatgaaa tatatggatt attttcaata ccaaatggaa ctgaagtatt
    11641 ggttgtaaat gatacaaaag aaactacctt agaaacgata agcttatttt acaaaatagg
    11701 agtaaaaaat ttaaagttta ctccatatat tgaaggaaaa atttataaaa atatagacat
    11761 agctataacg cctggagtaa agggaaaagt accaagttat ataaataaag taatcgacct
    11821 tggaaataga tatattgata tatctacctt tatagaaata ataaatggtc ttagaataga
    11881 tgttaaagaa atacgtaaaa atttaatggc atattctgag agtttaataa gtttagataa
    11941 tggagttaaa gataattata ggcaactgtt tttaaaaata gaagaacaag atgttatatt
    12001 gaatctatca aaagatggaa taatatttac ttcagcagat ggtataataa acacatttaa
    12061 taaagaagct ttaaaaattt taggtataaa tgaaaatcca caaggcaaaa acatagaaga
    12121 tatcatttct gaagatttaa atattttact tgaagacaaa gaaataattg atgaagtggt
    12181 atttacaaat aaaaaatata taaatgtaaa taaaaaaagt attttttcta tggggaataa
    12241 agctgggata tattataact tacaagaaat aacgtatata aaaaaattag aacaaaatct
    12301 tactaataaa ttaagagaac aaggtcagat agcaagatat acttttaaag atataaaaac
    12361 taaaaataaa aatatggtaa agtgtgtaga attggctaaa aaaatatcta aatcagacct
    12421 ttctgtatta ataataggag aaagtggtac tggtaaagaa ttattatcac aatcaattca
    12481 taatgcttcc aatagaagta atcaaccgtt tatagcagtt aattgtgcag cagttccaga
    12541 tagtctatta gaaagtcaac tgtttggata tgaaaaaggc tcttttacag gagctttaag
    12601 agaaggaaaa aagggtctat ttgaacttgc taataatgga actatatttc tggatgaaat
    12661 tggagatatg cctccattgc tacagacaaa gttactaagg gtattacaag aaaagcaggt
    12721 tatgcctata ggttcccata atgttataaa catagatgtt agggtcatag cagcaacaaa
    12781 caaaaactta ctaaagatga ttagagaagg aaaatttaga gaggacctgt attatagact
    12841 aaatgtattg ccaatagatg taccatcatt gaggaataga aaagaagata taataacact
    12901 tatgaatttc tttttgaaaa acaatataag actttcgcca gaagttataa ctattttaga
    12961 aaaatataat tggccaggaa atataagaga gttacaaaat gttgcttctt atgtaagtct
    13021 aatgtgtgat agtatggttt ttagagatga cttaccacca tatataaggg tagaatgtgc
    13081 taacaattat gaagatggat ttggttatac aagaaaagaa tttgaggaaa tactgaggat
    13141 tctatatgaa agaagagagt catcctctgg aattggaaga gggtttataa tcgaaaagct
    13201 tatacaggaa ggtattgaga tttctgaaag caaagttaga aaggtgctat cttatttaag
    13261 tgaatgtgga tacatatcat ctaaatctgg tagaggagga agtcaaataa cctcagaggg
    13321 gataaaactt tataataata taaattaagc taagtatttg atattgaaat cacatatttt
    13381 gaatttagat atttaaataa taataaactt ttatatttat agagattaat ttatattatg
    13441 tcagaaagaa tattgtaatt tataattaaa tattaatagg tttttaaaat aggattagat
    13501 aggtaatagg ttaagttaga ataacccatt acctattttt atttgtaaga aaagtgtaca
    13561 tagaattaga agtaaaaaat acaactaata aaactattga aaatactaga taaataataa
    13621 ataaaaataa ttatagattt tggcatacat attgctaatt atagagataa gacgacaaaa
    13681 taattgggag gtttaatgat gaaatacaaa acaacaggga cttgtgctac agaaattgaa
    13741 tttgaagtaa aagaaaataa agttacaaat gtaaacttta taggtggatg tgatggaaat
    13801 ttaaaagggc taaaagtatt agttgaaggc atgaatatag aagatgtaat acaaaagtta
    13861 aaaggaatag agtgtaaaac aaagccaaca tcttgcccag accaactgtc tctagcattg
    13921 gaaaattata tgaatataaa gtaatacata aaacaatcga ttagttagga gtttaattat
    13981 gaaaccaata atagggattt taggaaattt aataataatg gaaaatggta tgtttccagg
    14041 tcttgaaagg tcatatgtaa ataatgatta tataaatgca gtgctaaaag gtggcggtag
    14101 tccagtaata attcctgtaa atacagataa agaagttata aaaaaacaga ttgaaatggt
    14161 tgatggagtc ttaatatctg ggggatggga tatcaatcct caactgtatg gagaagaaac
    14221 aagagaagaa acgacattta tatatccaga agtggatgaa tttgatttaa ttgcaataag
    14281 tatagcatta gaacttaaaa agcctatatt aggtgtatgt aggggactac aaattttaaa
    14341 tgtaagttta ggaggaactt tatatcaaga taataatctt atagaaggaa gttatataaa
    14401 acatacacaa tcttctaaaa gacatgtagc tactcataaa gttgatgtta aagaaggaag
    14461 tattttagag ggaattttag gaaaacaatt acttacaaat agttatcatc atcaaagtgt
    14521 caatcagctt ggaaaaggat taaaagccat agcatactca aaagatggta taatagaagc
    14581 tattgagaaa gaggatgaaa attttgtagt aggagtacag tggcatccag aaatgatggt
    14641 agattactgt gataaaatgg aaaaactatt taaatatttt ataaatattt gttcgaattt
    14701 ataatatacc ttggggggat tgaacatgaa cgaaaagaac aaaatgggat taataagtat
    14761 tatactttta ggtattaatg cagtagtagg agctggagtt tttctattac caggagatgc
    14821 aatgaaatca tttggtgtag caagtatatt tgtatatata tttgatatgt tgttagtttt
    14881 atctatggca ttctgttttg ctgaggttgc aggtaaattc aataaaaatg gtgctgccta
    14941 tgtatataca aaagaagctt ttggagattt ttgtggtttt gaagtaggtc ttatgaaatg
    15001 ggtaatagga tgtatttctt ggggagcttt aatagtaggt tttcctacat cattatcagc
    15061 agtatgggct ccagcaggtg aaccacatat acaaaaaatt ataattgtag ctatgatagt
    15121 tgggcttaca attataaact tattaggtgt atctctatca aaaattgtac aaaatgttat
    15181 aactgtaggt aaactaattc cattaatact atttatagga ataggtatat tttttataaa
    15241 aggagttaat tttacttctt caacaatggt acctccagga gctggagcaa cagagtttgg
    15301 agcagcagca cttttaatgt tttattcatt tacaggattt gaatctatag cagttgcagc
    15361 agaagatatg gaaaatccac aaaaaaatat accaatagca attataagtg taatagtaat
    15421 tgcatcaata atatatatat taaatcaagt tgtatgtgtt ggtatactag gagattcgtt
    15481 atctagtaca tctacaccag tggcagatgc tgcaagaata tgctttggaa atatgggagc
    15541 tggattggtt acctttggaa cattggtttc tgttggtgga atttgtatgt gtggtgcttt
    15601 tgtaaatcca agaagttgtg tagctttagc tgatgataaa atgttaccga gaatatttgc
    15661 aagaaaagat aaaaaaggta caccatatgt agcgataata gctactatgt taatcactat
    15721 accaatagct ctatctggaa gttttgctga attagcagca ataagtgcag ttgctagatt
    15781 catacaatac ataccaacat ctttatccgt attagtgttt agaaagaaaa gaccagaatt
    15841 agtaggtact tttaaaactc cttttggagc agtgattcct ctaattgctg tatgtgttgg
    15901 aacatggttg ttattccaag catctatgca tcaattaatt atgggattag gagctttggc
    15961 aattggagta ccattatact ttataatgaa gtcttataat agaaaagtct atggtgaaaa
    16021 tttaaagaaa atagtttaat tatgttataa caatttattg agttaaaatt agacattggc
    16081 agaaaattaa atacaaataa gtatctacaa ggctatatta aaatattatt aattttttat
    16141 tttaatatag ccttatattg ttatcaataa atgaaaaata ttgtaacaac agaagaacaa
    16201 tagtattatg tttatagaca aaaaacttat taggaggtaa atttatgcca acaataacat
    16261 taaaaaatgg tgtagacgta cttattagag aaggtgtaag agaagatgct caaagcatta
    16321 tagattttta taatgaagtg ggtggagaaa ctcattttct gtcatttgga aaggatgaat
    16381 ataaaatatc tttggaggaa caagaaaatg ctatagaatc agcaaaagca tctgataatt
    16441 ctgttaaact gattgcattt atagatggtg aaatagttgg gattgcaacg attgattcta
    16501 atcaaaaagc aaaaggaaag catgttggag tattaggaat tgttgtaaaa gaaaaatatt
    16561 ggggaattgg attgggtaaa aggcttatgt tagaccttat agaatggtgt aaatcaaatg
    16621 gaataaccaa gaagataact cttgtcacta atgaagaaaa ttataatgct ataggattat
    16681 acaaaaaagt tggatttgaa gtagaaagca tactaaagaa agaatgttat tataatggtg
    16741 tttatactga tttaatagga atgtcacttt tattgggaat ataattagtg tacattttat
    16801 ctcgaaaaaa gtatattaag tatggtataa ttaaaaaaga atataactta atataatttt
    16861 ggaggacgaa ttatgaaaaa tctgtgtaaa atatcagatg attatttaaa cagcaagctt
    16921 aagtatttaa agttattatc aaaacaatat ccaagtatat caaaagcaag tacagaaata
    16981 ataaatttag aggctatatt aaatcttcca aagggaacag agcattttat aacagatgta
    17041 catggtgaat atgaaccatt tgtacatgta ttaaaaaatg gttctggtgt aataaagaga
    17101 aaaatagaag aattgttttc aaatacaata agagacagcg aaaaaaaaat gttagcaact
    17161 cttgtatatt atcctgaaca aaagttagac ctaataatta agcaagagga aaatatagat
    17221 gatttttata gaataaatat ttatagactt atagaacttt gtaaatatgc ttctagcaaa
    17281 tatactaggt ctaaagttag aaaactgtta ccagaaaatt ttaaatacat aatagaagaa
    17341 cttttgcatg agcatgttaa aagtgaacat aaagaagagt attataaaag tatagttgaa
    17401 acaatagttg acataggaat agctaaggag tttataattg ctatttctac agttatacaa
    17461 aaattggttg tagatagact tcatgtaata ggagatattt atgatagagg tccaagacca
    17521 gatataattg tcgataagct tattgaacat cattgtgtag atattcaatg gggaaatcat
    17581 gatatattgt ggatgggtgc agcctcaggt gaaaaaactt gtatagcaaa tgcactgagg
    17641 atatcagcta gatatgcgaa tttagacatt gtagaagaca tatatggaat aaatctgttg
    17701 cctttggcca cttttgctat agaaatgtat aaagatgacc cttgtaaaga atttattcca
    17761 aaggttaatg accaaagtgt aacaacaaca gaaaagtctt taatggcaaa aatgcacaaa
    17821 gcaataagta taattcaatt taagcttgaa ggtgaggtta tcagacgaag acctgaattt
    17881 gaaatggaac atagactctt gcttaatatg ataaactatg atgaaggtac gattaattta
    17941 aaaggtaaaa catataaatt aaaagatact tatttaccta caatagacaa aaaagaccca
    18001 tataaattaa ctatggaaga aagaaatgtt attgataaat tagtatcttc atttagaggt
    18061 agtgaaaaat tacaaaaaca tgtttcattt ttgttttcta aaggaagtat atatttaaag
    18121 gctaactcaa atttactgat tcatggatgt gtaccgttaa atgaagatgg aagctttatg
    18181 tctatgaata taatgggaaa agagtataaa ggtaaggctc ttatggataa gatggagtct
    18241 ctagcaagag aaggattttt ctttaaagat aaggcagaag aaaaactgta tggcatggat
    18301 attatgtggt atttatggac tgggaaatgt tcatcattat ttggtaaaga tgatatgact
    18361 acatttgaaa gatactttat agctgaaaaa gagactcata aagaaaataa gaacccatat
    18421 tttaaactta gagaaaatga gatggcttgt aaaagattat ttgaagaatt tgatttagaa
    18481 cttgatgaat ctcatataat aaatggtcat gttcctgtgg agagtaaaaa tggagagagc
    18541 ccaataaaag ctaatggtaa aattctcgtt atagatggtg gtttttctag ggcttaccaa
    18601 aaaactactg gtatagctgg atacactttg atatacaatt ctagaacttt gcaattagta
    18661 tcgcatgaac catttaattc tgctgaagaa gccattgcaa atgaaagtga tatcttatcg
    18721 acaactgttg tagtagagca taaggcaaag agaaaaatgg tgagagatac tgatgaagga
    18781 ataaagatac aagaggaaat agaagattta aaactacttt taatggctta taagaaaggg
    18841 ctaataaaag aaatgtagat gttatagagg cacttcatga ttgaagtgtc tttttgttaa
    18901 tacttattaa atatattata aagattaata atagtagttt atattatact tactaagtga
    18961 atccaagata aatgggttca ctttttttat ttataaacat tattaaaaaa atatagatgt
    19021 tttggttata ttccttgtcc tttataaata gaattatata aacaaaggag gaggacaaga
    19081 gatgaataaa ctttctgatg aaataataaa ctctctttct acaactataa gagaaaaggt
    19141 agaaaaagtc tcaaacaata atctgaacat agaagaaatt aggttacgct cacaaaaacc
    19201 attgatacta aatgcaaact ctaaagatta tttttacaat caaaaaacta tgacacttga
    19261 tttaaatcaa caaaactcat atgtagtaac aagagaagat gtagagcaaa cttttcaaat
    19321 aatatgtaaa tattcaatac attcatttat ggatgacata aaaaaaggat tcataacttt
    19381 gagaggaggt catagagtag ggttagttgg aaaagcaata gtagaagatg gacaagtcaa
    19441 aaatataaag catatatcat ctttaaatat aagggtatca agggaaatta ttggatgctc
    19501 ggataagatt ttaagtcata tcataaaggg aaaaaatcag attaataata ctttgataat
    19561 atcaccacct caatgtggaa aaacaacttt aataagagat atagtaagaa atttaagtaa
    19621 tggtaatgaa gattatggat ttaaaggttt aaaagtggct ttagtagatg agcgtaatga
    19681 gatagcagga gcttatctag gtgttccaca aatggatgtg ggaataagga ctgatataat
    19741 agaaacttgc ccaaaagact tgggtattac aatgctttta aggtctatgt caccaaatgt
    19801 tattgtgaca gatgaaattg gaagtgaaaa agaaataaag gcattataca cagcattaaa
    19861 tggaggtata ggattaataa ctactgtgca tggagattca atagaggata tacaaaatag
    19921 aaaagaatta aatagacttc tggataaaga gttatttaaa aaggttataa ttctttctgc
    19981 aaaaagagga gcaggaacaa ttgaaaaaat ttatgattta gaagaaaaga gatggtattt
    20041 tgcaaattaa aataattatt atagctttct tgataggaag tagttatttg ataggtgaac
    20101 aaatatacaa aacttatact cgtagacata aacaattaaa cgatttaata agagttttag
    20161 aaattttgag gatggattta tcttttggac tttatacatt agaagaaatc tttaatagga
    20221 taggtggaaa taaagagttt tgtttttgga aatttttcta tcaaatatca gaaggacttc
    20281 acaatgaaca aagtaaaact ttggaaataa taatatcaga aaatattgat gtcttaagta
    20341 aagaaactta tctaggcaat aaagaaattg aggaactgaa aaatctaata cttactttag
    20401 ggaaaagcga tatagagtca caacaaagaa tgatagattt atctatagaa aatttgaaaa
    20461 aacaaaccta tgagacaaag gaagatataa acaaaaaagg cgtattgtat aaaaaattag
    20521 tgacattcat aggtataggt atatgtatta tattgattta atatggggag gtttattatg
    20581 gaaatatcat tgatattaaa ggttgcaggt gtcggtattc taatatcagt attgaatatg
    20641 atattggaaa aaacagatag aaaagattgg gcaggtctta ctacattagc aggtgtaata
    20701 atcgtattgg gtatggtaat aacagaaata agtgacttgt ttaatactgt aagaacaatg
    20761 tttcaacttt actaaagagg agggagtaat ttggaaataa tgcaattaat aggaattgca
    20821 atcatttcaa ctacactctg tttagtaatt aaaaaagata gaccagagat agcaaatttc
    20881 atagctataa taactggagt aataatacta ttgtcagtta tgtttaagct aaattttata
    20941 gtagatagta tacaagattt ggctaacaag gctaacatcc cgactatgta tatatcatta
    21001 ataataaaat taattgggat agcatactta atggaatttg cgatacaact ttgtaaagat
    21061 tgtggggaag gaaacattgc ttcaaaacta gaatttggag gtaaaataat agttatgtca
    21121 atgtctttcc ctatactttt gtccattgta gaaatggtgg tgaatataat tccatagatg
    21181 tgtatcttgg aatgaatata agtatattag agagctttcg ttgtattgag gtttatagag
    21241 tgaagagagg catggttgct tatgaaaaaa agatttttac caatgattat aggtttttta
    21301 tttactttct tttttgtaaa tatctttgct attatgatat ttgctaatga agtaccaagt
    21361 agtgaagata aagaatatgg tgaaacaaaa aatagcatag ataagtatat agatggtcaa
    21421 ttagacaagc tagatataaa tgagattcaa gactatataa ataaagaaat agttattaat
    21481 gatgttaatt taaaatcatt tgtaaaagat ttaattagtg gagaaaaaaa tatcttagat
    21541 ttattcaata aagatggatt gaagatattg atgtttgatg aatttaaagc aagtttaaag
    21601 gtagtagcag taattttggt actggctctg ttatcatcta ttttaaagag tctggaaaac
    21661 tctttttcat caggtgcagt aagtcaaata gcaacatata taatatttat cacaatggta
    21721 tcacttacac ttattggttt taaagatgta ttacagattt gctatgatgc aatagaccat
    21781 actgtaggtc ttatgcaagt tataatgcca atattaataa catttttact tttaattgga
    21841 ttcccaataa cgtcgactac tttgaatcct atattcatag gaggagtaac atttataaat
    21901 gtatttttta aaaattttct atttgtatct attactgttg catttggaat tttaataata
    21961 aacaatttat caaaaaatat aaggctaaag agatttttct cctttgtaaa acaaataaat
    22021 tatgtttcta ttggagctat gtttactgtt tacttaggtc ttgtatccat acaaggactg
    22081 tatgtaacca gttttgataa attcagtgta aagactgcta aatttgctat aggtaatttt
    22141 attcctgttg taggtggatt tgtatctgac tctgtggata ttttattatc ttcatctcag
    22201 cttataaaaa atatatttgg aggaataggg cttatcttac ttgttggaat ttgcttactt
    22261 ccagtaataa aaattttatc agtaatagta gtgtacaaat tagcagcaat aattgtagag
    22321 cctgttggag aggatggaat atctaatttt ttaaatgaag tggcaaattt aatgataata
    22381 atgctagcat cagtaattgc tataacagta atgttctttg taactgtagc tatcttgacc
    22441 tcgataagtg tcgtaagtca agggtaattt atatatcagt gaaaaataat tacaattaat
    22501 ctaatgtttt tagagaggag gatgctatgt tagagggcat aaaggcatgg atagttagtg
    22561 ttttgatagg agcatttata gtaaatatag tagatatgat tttaccaagt tctaagataa
    22621 aaccttatgt caacctagtt ttaaacttta tgtttgtatt tattgtaata actccagtag
    22681 taggattttt ttcaaaagat atgagtttag aagatagaat attaaaatct atgggaaact
    22741 acaacaagca gtatgtagat agtacaaatg ctttggcaaa agagactgga aataatagtc
    22801 tatccaaggg atatgaggat gggttaaaag aagtacttaa attaaaactt gatgaatatg
    22861 gttatgattt agaagatata gagcttaatg gggcaaatat aaataatata aaaataaaag
    22921 aaaagaataa tagtgcaaaa agtaataaca gttccaatga agaaaataaa aataatagta
    22981 ctaaaagaga ggaagaaaac ataaactcta atgacaaaga aaattctaaa caagtcttca
    23041 aaaaaggtac agagtatggg ttgaacctaa atgaagaaaa attaaaaaac gacttaataa
    23101 aggtgctgga tgtttctata gaagatatac aaattgataa ataggagttg ggagaatgtt
    23161 gaaaaactta aatgacaaag ataagagaaa ggtatattca ctaataacta tagcaggaat
    23221 atgtgtggtt tcattagtat tattatcttg ttttcctagt agcaaaagcg ataaacaagt
    23281 tggaaaaaca gagactaata aaaatgctga aaagcaagtc actaaagaac aagaaaaaga
    23341 tgatttagag tcaaaattaa cagcaatact atctaaaatt gatggtgcag gagacgttga
    23401 tgtaatggtt acatttgaat caagtgaaga aatacaacct gcttttaatt caaataatac
    23461 aacagaaaca acagaggaaa aagatgcaca aggtggagaa agaacagtta cgacttctag
    23521 tgaaaataaa acaatgataa cttcaaattc aagtgaccct gtagttataa aaactacaga
    23581 gccaaagata aagggagtga tagtggtagc aagtggagca agtgacccaa gtgttaaaga
    23641 gacactttat agtgcagtac aaacatcatt acaagtagct ggtcatcaag tagaaatata
    23701 ttctaaataa atacatataa ccggggggat aaatgaatga agtttaatta taagggaaga
    23761 ggatttgtaa taataacttt aactgcaatg ttagtggtag taggaacagt gaattatcaa
    23821 ttaagtaaga aatctttatt agaaacatca aaagagttta aggcatatga agaagcacag
    23881 ttgcaaaaaa atactgatga tagtgatagt agtaagacag aggattctag taatgtggat
    23941 aaacaaggtg gtaaggaaag tgctgatatt gatatagtcg atagcaaagc tagtaaagta
    24001 aaagaaaagg caactgagac aagtaaggaa ataaaagctc aattatcatc agagaaaaat
    24061 atgaaaaagg catcttatat tttagatatg aaaatgaata gagaaaaaca aagaaatgag
    24121 ttagttcaag atttaaatga aatgataaat aatccatcta caacagaaga atctagaaaa
    24181 gaagcttcta atatgaaatt aaatatagtt aaaattcaag aaaaagaact tcaaatagaa
    24241 aaccttttga gtacaaaagg gtatgaagaa gcgttagttt atataagcga taacaaagtt
    24301 aatgtagttg taaatgaagc taaattagaa aagaaagatg cagcaaaaat atttgattta
    24361 gttgcagaac aagccaatgt gaagtatgaa aatattaaac ttacaaataa taatagtaat
    24421 aagtaaagta taaacctcag aattaactga ggttattttc ttgcaaagta gacttgtatt
    24481 tggtattatt atacttataa aaatagttcc ttaaaatcag gaggtaagtt ttaatatgga
    24541 agataataaa tttggacaag taaaaatatc taatgatgta atagctacaa tagctggttt
    24601 agcagcatta gaagttgaag gcatagaaac tacagcaaca ttaacagata agttgttaaa
    24661 aaataatgga gtaaaaatac aaatcgaaga agaggatgtt aatttagatg taatggttac
    24721 gataaagtat ggaatgtcaa taccagatac agcttttaaa gttcaagaaa atgtaaaaaa
    24781 tactgttgag acaatgacag gactgaaggt ttctcaagta aatatacaca ttcaaggaat
    24841 cagctttaag aaggataaag ttgataaaga agaagcaaaa gcaactaaga aaaattaata
    24901 ttagccctct gaaaagtcag agggtttttt gctggtaatt gattttatat ggataattaa
    24961 acttaaagga gaattttgat tgatgaaaaa agatagggca caaaagagta caacaagaga
    25021 atatataatg aaacttatat accaaataaa tattaataaa gaagattttg aaactttaga
    25081 agataaagta gataattttt taaaagataa ttcagaacat attataaata gatataaaga
    25141 acttgcactt caatactcaa aaaatacaaa tttaaagtta gaagatactg aaattgaaga
    25201 tgttatagac aaaaaatata taaatacagt atgcaaagca ttgaaagaaa atcatgacaa
    25261 aatagatgag ttaataaata agcatgctaa aaactggaca gtagatagaa tgccaaaggt
    25321 agatgtttct atacttagat tgtctgtgtg tgaaatactt tatttagaca ctcctaataa
    25381 agtatcaata aatgaagcag tagaacttgc aaaaatatat tgtgatgata agtctcctaa
    25441 atttataaat ggtatattgg gaagtgttgt tgatgaaatt gggaaataat ataataattg
    25501 gaattgatac tagctgctat actacttcta tagcagctat ctctttagat aagaaagtta
    25561 tattcaacga aaaaataatg ttagaagtaa gggataattc aaaaggttta aggcaaagtg
    25621 aagctgtatt tcaacatatc aataatttag ggattcttag tgataggata aaatctttta
    25681 aagataagtt taatgtagaa ggagtttgct catcaaaaaa accgagacct gttgaaaact
    25741 catatatgcc tgtattcaat gtaggtcata attttggaaa attattgtct agtatatatg
    25801 gttgtaggtt ttatgagact actcatcaag agaatcatat tgaagcaagt ttattaaata
    25861 gtaaattaaa aaataataat aaatttattt ctgttcatat gtctggtggt actacagaga
    25921 tacttttaac aagcaaacaa gatagtcatc ataatgtatg tgatactaat ttaggtaaaa
    25981 ttgccaaaat aagtattaaa aaagatgata aaagtaagtt atacaataat tttggatata
    26041 atatagatat aattggagga agtaaagata ttagctttgg tcaacttata gatagagtag
    26101 gaattaagct tggatataaa tttccttcag gaaagtattt ggatgaaaat gctttaaatt
    26161 gtaatcttaa aatagaaagt ggtctgaaaa cttctgtaag agatgggtat atgaatttat
    26221 caggattaga aaatcaggta aataagatta taaatgataa tggagataat actaatcaaa
    26281 aagaatatat atctaaatta gtattagatt cagtagttag aaatatgttt aaatctctag
    26341 tgtatttatg tgaaacttat aatgtaaatg aagtagtatt tgctggtgga gtttctgcaa
    26401 gtaagtatat tcttagagaa ttaagcatga agttaagaaa aaagcatata gaagcttatt
    26461 ttacagaacc acaatattca actgataatg ctgtcgggtg tgctataata ggattgaata
    26521 actttttagg agaaagagta tgaaactaag agctttagat ataagtgaag caaactcata
    26581 tattaaaaga attttaataa acgacccaat actttctaat cttaaagtta aaggagaaat
    26641 ttctaatttt aaggttcata gtagtgggaa tgtatattta tcacttaaag atgaaacatc
    26701 aaagttaaac tgtgtaattt ttaaaagtaa ttttaatcgc aatttaaaat tagataatgg
    26761 tgtaaaaatt atagctaatg gatacatatc agtctatgaa agagatggtg cgtatcaatt
    26821 atacattaat gaaattgaaa tagagggaat aggaaattta cacatagagt ttaatagatt
    26881 aaaggaaaaa cttaataaag aaggattatt tgaccctaaa tacaagatac ctatacctaa
    26941 aatgccaaac tcaattggcg ttataacatc tccaacaggt gctgttataa gagatataat
    27001 aaatgtaata aaaagaagat atccgaaagt taatataaag ctttatccag taacggttca
    27061 aggagataaa tcagctgaag aaatctgtga agcaattaga tttttcaatc atatgaagaa
    27121 tgttgataca cttatagttg gtagaggtgg gggttcaata gaagaacttt ggtcttttaa
    27181 tgatgaaatg gtagcaagag aggtttttaa ttctcaaatt ccgataatat cagcagttgg
    27241 gcatgaaacg gattttacta tttgtgactt tgtgtctgat atgagagccc caacgccatc
    27301 agcagcagct gagattgcta ctccatcatt ggatgatata aactataaac ttggaaacat
    27361 aaaaagtagg atgagtaagt ctcttacaaa tcaaatagag ctagaccaat ataggttaga
    27421 aacagtattt aataagataa ataactattt agattcgtac acaataaaag ataaagttat
    27481 acaattagac aaaatatatg ataaaataat ttttggaata gaaaataatt taaagttaga
    27541 agatgaaaaa ttagtaaaaa ttggagcatt actccataat ttaagtccat tagctactat
    27601 ggatagaggt tatagtataa ctcaaaaaaa tggaaaagta ataaatagta taaaaggatt
    27661 aaaaataaag gatagtatag atatagtatt aaaagatgga aatttagaat gtatgataga
    27721 taaaattgaa aataaagagg gatagtatga atttaaccta cgaagaagct tataaaagat
    27781 tagaaagtat tttaagtgaa ttagaatcta aaaatgctag cttggatgaa tctttaagcc
    27841 tatatgaaga aggtataagc ctttataaac attgtaataa gcttttagat gatgctaaat
    27901 tgaaaataag taaatttaat caattgggaa tagaagaaga ctttaaaata gaggaggaat
    27961 aaaattggaa tttaaacaat gtctaaaaga aaaagcaagt tttgtagaaa aagtacttaa
    28021 agaatatatg cctaaagaag aagggtatca aaaaactgtt attgaagcta tgaactatag
    28081 cttaagtgct ggaggtaaaa gattaagacc aatacttaca ttggaggctt gtaaaatagt
    28141 tggaggtaat gaagatgaag ctattccttt tgctattgca attgaaatga tacatacata
    28201 ttcactaata catgatgatt tgccagctct tgacaatgat gatttaagaa gaggaagacc
    28261 aacaaatcac aaagtatatg gagaagctat ggggatttta gcaggagatg ctttgttaaa
    28321 ctatgctttt gaagtaatgc ttgcaggctc aatcaataaa gaaaatccag aaaagtatct
    28381 aaaagctata aatgaaattg ccaaaggtgc tggtatatat ggaatgatag gtggtcaagt
    28441 agtagatgta gaaagcgaaa ataaacaaat tgaaaaagaa aaattagatt atatacatat
    28501 gaataaaact gctgcaatga tggtaggctg tatgagagca ggagctacta taggtggagc
    28561 aaattctgaa caaatggaag aaataactaa atatgcaaaa aatatcggat tatcattcca
    28621 gatagtagat gatatactag acatagtagg agatgaagct aagttaggta aaaaggttgg
    28681 aagtgatata gaaaatcata agtcaacata cccatctctt ttaggtttag ataaatctaa
    28741 agaaattgca cataatttga ttgatgaagc aaagaaaagt atagaaaaat tatctgatga
    28801 tgtagatttt ttaaagggat tggctgaata tataatagat agagaatact aaaatataca
    28861 gctaaaatcg aggagggaaa aatggatttt ttttcggaga tttttaacaa tggggctttg
    28921 ggaataagtc tgattgcttg tttcttagca caatttataa aaatatttac tggtaaggaa
    28981 aaaagaattg agttatcaag aatacttatt tcaggaggta tgcctagttc ccatagttct
    29041 tttgttacaa gtttagctac agtggtaggt attgaaaaag ggtttaattc tactgatttt
    29101 gctataatta ccgtgcttgc cttaattata atgtatgatg cagcaggtgt tagacgggct
    29161 gttggtaaac aagctactat attaaatcaa atggtggcag atatacagca tggaaagcat
    29221 atagagcaga agaaattaaa agaattaata ggtcatacac cactagaagt ttggtttgga
    29281 gctttacttg gaatagtaac agctttaata ttgatgtaaa ttgaaaattt acagaataaa
    29341 ggtgaggata atatgtataa atatttagat aaagtaaatt ctccaaagga tataaaaaat
    29401 atgagtatag aagaaatgga tttacttgca aaggatataa gaaagttctt agtaaaatct
    29461 gtttcaaaga caggaggaca cttagcttct aatctaggag tggttgagtt aacattagca
    29521 cttcataaag tatttgatag ccctaaagat aagattgtat gggatgtagg gcatcaatct
    29581 tatgttcata aaatagttac tggaagaaaa gattgttttg tatctttgag acagtttaat
    29641 ggactaagtg gttttccaaa ggagaatgaa agtcctcatg atatttttga tacaggacat
    29701 agcagtacat ctatttctat agctacaggt attgcctgtg ctagggatat aaaaaaagaa
    29761 aactatagtg ttatatctgt gataggagat ggttctataa caggaggtat ggcacttgaa
    29821 gctttaaatc aattaggata tatagatacc aatatgatag taatccttaa tgataatgag
    29881 atgtccatag ataaaaatgt tggaggaatg tctaaatatc tgtcaagtat tataagaaac
    29941 tcaacagttg agaaaatgac agatgaagtt gataaaattt taaatgttac acaaacaggt
    30001 gaaattttat ctaagactgc acatagattt aaagataaac taatgtatag cttttctcct
    30061 caggactgtt cattttttga ttcattaggt ataagatatt atggacctat agatggccat
    30121 aatactaaag aactaataga tatattgaga aaagctaaac acaaaaaagg gcctgttctt
    30181 ttacatgtaa ttacgaaaaa aggaaaaggg tacagatttg cagaagaaca acctgataaa
    30241 tatcatggag tatcaaagtt tgatataaag acaggtgtta catctgcaaa agttaagtct
    30301 atgtcaatta gtgttggaga aaaacttgtt gatatggcta atagtaatga aaatatagta
    30361 gcaataacag ctgcaatgcc atctggtaca gggttaaacc tgtttgaaag tgcatatcca
    30421 aaaagatatt atgatgttgg tatagctgaa caacatgcaa caggatttgc agcaggtctt
    30481 gcaaaaaatg gtatgaaacc ttactttgct gtgtactcat catttttgca aagggcatat
    30541 gaccaagtta ttcatgatgt atgcataaca aaaaagccag ttacttttct tatagataga
    30601 gctggattag ttggaaatga tggagaaact catcatggta tgtttgattt aagttactta
    30661 aattctattc caaatattgt agtaatggct ccaaaagaca caagagagat ggagcttatg
    30721 atggatttgt cattaaaatt agattgtcca ctagcaatta gatacccaag aggaagtagt
    30781 tattacctag ataagggaga gtatggagag attgtactgg gtaaatatga ggtattagat
    30841 gacggtcaag atacagtcat actttgtatt ggaagtatgg taaaacatgc tttagaggct
    30901 aaagaaatat tatcaagaga aggaataaat ccgacaatag ttaatgctag attcttaaag
    30961 ccaattgatg aaggtatgtt aaaagcatta ttaaaaaatc ataaaaatgt agttactata
    31021 gaggataata ttgtaactgg aggatttgga agtagaataa ataagtttat tatagataat
    31081 gaatataacg taaatatact taatatagca ataccagaag aatttgtaaa acatggcaat
    31141 atagatgaat tatatgattt tgtaggatta tcgccaaaaa gtattgctga taaaataagg
    31201 aaattagtta ttgagtaaaa atctaatgta gatattgtaa attaaaattt atataaaata
    31261 tagaatttat caattagaat aaatatcaag tgtgttactt taagctactt tagttatcat
    31321 taaagtagct tttaacagaa aggtaattgt atgaaaaaaa gaatagattt attattagta
    31381 gaacaagggt actttgaaag tagagaaaga gccaaaaaag caataatggc tggattggtt
    31441 tttgttgata atcaaaggtg tgataaggct ggtacagaag taaaagaaga ttgtagtata
    31501 gaagtaaaag gaaatccaat accatatgtc agtagaggtg gtttaaagct tgaaaaagca
    31561 atgaaaaact ttgatttgac tattgatgga aaggtatgta tggatatagg ggcatccaca
    31621 ggtggtttta cagattgtat gctcaaaaat ggagcaataa aagtattttc tatagatgtt
    31681 ggttatggtc aacttgcatg gaaattgaga caagatgata gggttgtgtg tatggaaaga
    31741 accaatataa gaaatgtgac aatagaagat acaaagcagt ttgctgattt tgcatcaatt
    31801 gatgtgtctt ttatatcgtt aaagttagta cttccaaagg caaaggagtt agtacgtcat
    31861 gatggggaag ttgtcgcttt aattaaacct caatttgaag caggaagaga aaaagtaggt
    31921 aaaaaaggag tagttagaga aaaatctaca catatagaag ttataaaaat gatttctgat
    31981 ttctcagtcg aaaatggatt tgagatttta gggttagatt tttctcctat taaaggtcct
    32041 gaaggtaata tagaatatct aattcatttg agaaatggaa atgaaggata tgaatttgat
    32101 ggtgagacat acaataacaa aatagtagaa gttgttgaag cttctcataa tttagacaaa
    32161 taggttaaaa gggggcttag atttgatcct cgaattatat atgaaaaatt gtgccttagt
    32221 tgaagaacta aggttgaata ttgataaaaa cttaaatata cttacaggtg aaactggttc
    32281 aggaaaatct ataataatag atgcacttgg actttgttta ggtgataaat atgataggtc
    32341 ttttttaaga aaaggaacag ataagggact tgttgaggct gtattttttt cagacaatag
    32401 atatcttaaa aaaatattag aagaaaatga tataagtatg gaagatgata atttattggt
    32461 aataactagg ttgatatact cagatggtaa gagtactgct agagtaaatg gaaggactgt
    32521 taaagtgtct cttcttaaag aaattgcatc tacacttata gatatacatg gtcaacatca
    32581 aaatcaagct ttgtttaata aagatactca tttaaaattt ctagaccttt ttggagaaaa
    32641 tgaattggaa gagtttaaaa ttgcttataa aaatgtgtac cataagtata gtgaagtaaa
    32701 aaaagcttta aattgcttga cagaaaataa agatgagatg caaattcaac gagaaataga
    32761 tttattaaga tttcaaataa atgaaattga agctgcaaat ctaaataaga atgaatatga
    32821 agatttatta aaacaaagag aagtttatag aaatagtgaa aagatatata ataatctaaa
    32881 ttcgagttat agcaagttac ataatggtga gtataatgtt attgacctaa taggtcttgc
    32941 atctaaggaa cttaatgaca tatctaaata tgacagtgtt ttaagtgaat atagtgatac
    33001 tgtagaaaga atcatgtatg agttacaaga catatctggt gagataagaa attacaaaga
    33061 taatatagac tttgaacctt atgagctaga gcagattgag cttagaatcg acgagattaa
    33121 taacttaaga agaaaatatg gagacagtat agatgatata tttgagtatt atggaaaaat
    33181 taaagataga ttagatgaaa tattaaacag agatgaaaga gttgaacagt taagaagcaa
    33241 actgatgaat atagaagaag atttaaaaat aaaagccagt aaattgacta aagcaagaat
    33301 agaagtagca actactttag aaaaaatact tcttgatgaa ttaaaaagtt taaatatgaa
    33361 aaatgtaatg ttcaaggtta attttgaaaa aggcccattt actttagatg gagtagatga
    33421 tattgaattt atgatatctt ttaacttagg agaagatatt aagcctatat ataaagttgc
    33481 atcaggtggt gagatgtcca gatttatgtt agcgtttaaa accatattgg ctgatataga
    33541 tgatattgat acattagtgt ttgacgagat agatactgga ataagtggga tagcagcaca
    33601 gatagttggt gagaaattga gtgatatagc aaagaaaaaa cagataatat gtataactca
    33661 tttacctcaa attgctgcaa atgcagacac tcattattgt atagagaaag atacttcaaa
    33721 taataggacg tttaccaatg ttagtaagtt aaatgaatct caacgaaaaa atgaaattgc
    33781 cagacttata gcaggtaata atataacaga aaaaactatt gaacatgcaa gtgaaatcat
    33841 tgaattggct aaaaaatgtt agtgaaaaac aagcatttta ataggtgtaa agaattttta
    33901 tagaaatgct ttacacctat tttttataat gaaattattt taaaatatct agtgcctata
    33961 ttgaagaaaa gtagatttaa aaatagaaga aaatttgtat aaatttgtaa ctttgaaatt
    34021 tctaaatgct taagtataat attatttatt aaggtagtag tgagggggac ataaaatgaa
    34081 taaaaaagat actatgcact taatttttac aattgtaatt tttattttat tatggtatat
    34141 tgtggtagca gtaagtgaga ttaataaaaa tattgaaagt tgtagtaaca aattagatta
    34201 tttgtcacaa gagattatga gtactaaatc ggatattagt aatactataa atgaagaaat
    34261 gtcaaaaagt tatataacaa agagtattga cttaaaagta aaaaaaatcg agaaaaaaga
    34321 gtgtgttatt gatgtagatg ttcaattaag taaacttgga aaaaatggaa aagtattttt
    34381 tatgtataaa gaagatagtg ataaatggaa tgaaactgag atgacaaaac atggagaatt
    34441 atcatatgca tgtgaaataa agataaatac aggaagtgaa tatgactata aagtagttac
    34501 aagtggagct atatctgaaa gttctgatgt gcaaaaattg actaaatctg attatatgcc
    34561 tgaacaaccc atatttaatt ctgggataag agataataga gaatacttta ttgaaatagt
    34621 agaaaatagt aatcttttca atcatgagag tgaaaagtca aaaaataaag tttatgataa
    34681 tattagatta gaaaaagtag atattattgt aaatgaagga aaaaaagaca ctatatacaa
    34741 agccaaatta gctgaaggct tagatgatgg caaaactaat aattcaaata gaaatcaagt
    34801 gaattatgaa gtaagttttc ctaaaaggga tattgatggc ataatttata ttaaagctaa
    34861 acttacatac aataatggag tagaatatac aaaggatata actgaagata taactatggg
    34921 attacaagat ttagaaaaat aaatacatat ttaaataaat attcaaatag atttgttcaa
    34981 taaaatagag tataaataaa actgtagtag ttttacttat actctattaa aaaattataa
    35041 ttttaattcc atatatctag ccccttcaat tggattataa gtataaggtt ctatatcata
    35101 aaaaccaaac ttttcgtata atccttgtgc acttttcatg cttggaagag tatctaatct
    35161 catgtgtgta tatccaaatt ttttagcttc ttcaatgatt tcttccaata gtatttttcc
    35221 tatttttaat cctctaaatt gatttcttac atataatctt tttaattcac atattttacc
    35281 ttcaagtttt tttaaagcaa cacaacctgc caaattttca tcaacaaatg ccaatatcaa
    35341 tgagcctgaa ggttttttat attttcctgg aagtgttttt aattcattat taaagtcttg
    35401 aaaacataag tctatattta gagaatttga atattcagta aatagaagtt ttacgttttc
    35461 aaggttttct aaatcttttt cttcaacaaa ttgtaaagtt atattttgag ccattttatc
    35521 cgccattata tacacatgtt tatataatga cttcacctcc ttgatatatg tatatttttc
    35581 ttaatatcaa ttagatttta ataccattac tttttcacca ccatagtcaa gctctccatt
    35641 aaactcaaat ccaaaatctt tataaagctt aatagccatt ttattgtctt cgaatatact
    35701 aagatatagt tcatcacagt tatattcatt tttaagatga tttacaagaa aatctaatga
    35761 tgcttttcca tatcctttac cttgatattt tgaatcaatc ataaatctat caagccaaac
    35821 tctatcatct tctaaacgac catacatagc aaatcctatt aaagaatttt catcatatat
    35881 tccaacaggt acccaagctg ttataaattt agattcagca atagaaagtg cattgctttc
    35941 tatataatct aactgacttt tatctacaga caaactaact aaatcatgcc aattatttat
    36001 gtctgcaatt cttacattta atttcaagat attaccgccc ttcaaacttt ttgttacaat
    36061 ctaatactat catattatgt attaaaaatc acttattaag attttaaata aactttttaa
    36121 atgaataaat tctcaggaaa aaggaattat aaatacataa taatacagca taggagtaga
    36181 tggatatatg aacaaaataa ataaaaattt caaaaatatt tggataatat taggagctgt
    36241 atcgattttt accatggtta taatttttaa taaaaattgt aatgttaata aagagactca
    36301 aatagaagct tttacaatta agaatcatga taaaaaattt gtatatccta tgggaaatat
    36361 aattggagta aaagcaaata cagatggtgt attggtctta ggatatgagg aagaggatgt
    36421 agactatatt ggaggcatac aaatcggtga taatatagta aaaatagata ataaaaggat
    36481 aaaaaatagt caagatgtat cagagatttt gaataagatt aaaaaaagta aagttgaagt
    36541 gacttttgag agaaaaaata agtataaaac agaagtaata gagactaaaa aagaaaatgg
    36601 caagtataaa cttggattat gggtaagaga taaaatatct ggaattggaa ctatgacttt
    36661 ttacgaccct agtatggaaa agttcaaagc aatcggtcat gccataaaag attcggatac
    36721 taatgaacta ttaaagataa agcaaggata tatatataag ccagaacaat taaaaatagt
    36781 aaaagctagt aatgaaaaag taggtaaaat aaaaggagat tttaatgaca gcaatttaat
    36841 gggtaatttc tcaaataatt cagagctagg tataagtggt aatattacag aaaaccataa
    36901 taaagagttt aatgtagcaa ataaagaaaa gcaattaata gaagttggaa ggccgcaaga
    36961 tgtaaaaata ggagatgcag taattctttt tgaggataaa aacaaaaata taacaagcta
    37021 tgatataaaa atagaaagta tagtatatga taaaggaaat tatagagata tggtaataaa
    37081 agtagtagat gacaagttat tggaatacac aggaggtatc gtacagggga tgagtggagc
    37141 tccaataata caaaataata aaattattgg tgcaataact catgttttta gagataatcc
    37201 gaaaaaagga tatggtattt ttatagatga aatgataaaa ttgtaggtga ggcattaaaa
    37261 aattttatta ttttatcaat tatctaggag gaatataatt ttggagtgtc gaatatgctt
    37321 tagagtagat aattaggaag caattgtgta aaaagtttag ttttctgtaa taagaagatg
    37381 ttttttaatg gggggatttt tagtggaaaa aatcaaaata gttttagcag atgacaataa
    37441 ggatttttgt caggtattaa aagagtattt gtctaatgaa gatgatatcg atatattagg
    37501 catagctaag gatggaattg aagcattaga cttagtaaaa aagacacaac cggacttatt
    37561 aatactagat gtaataatgc cacatctaga tggattaggt gtaattgaaa aattgaatac
    37621 tatggatata cctaaaatgc caaaaataat agtactatca gcagtaggtc aagataagat
    37681 aactcaaagc gcaataaatc taggagcaga ttactacata gtaaagccat ttgattttgt
    37741 tgtgtttata aacagaatta gagagctagt ttctaataga gttacacaag ttgagccaaa
    37801 acctagacca gttcaagaga ctcaaatgac tagaagtgat tttgttaaga atgtaggaaa
    37861 tatagagaca gaaatcacaa atataataca tgaaatagga gtaccagctc atataaaagg
    37921 atatttatat ttaagagaag caataaaaat ggttattgat aatgttgagc ttttaggtgc
    37981 agtaacaaaa gagttatatc caagtatagc taaaaaattc aatacaacac caagtagagt
    38041 tgaaagagca ataagacatg caatagaggt tgcatggagt agaggaaaag ttgacacaat
    38101 aaatcaatta tttggatata cggtacacaa tactaaagga aaaccaacta attcagaatt
    38161 tatagcaatg attgctgata aattaagact agaacatagt atggttaaat aaacaagaca
    38221 taaaaagtaa ggctttttaa ttaaggcatt ggctataaat gcgtattaca agcagcgaaa
    38281 cggtataacc actagggtta taccgtttcg ctattttaat aaatataaaa attttcttta
    38341 ttatttgctt actatatcaa tataataatt ttattatact atggatatag tatgtgtctt
    38401 tacaagttgt aaactgacag tggtttattt tttaatataa atattgactt tgatgcaggt
    38461 aaactttgta tttttaagcg tattgtggaa tatgttaaat aaaaaaatga tgaaatatag
    38521 tattgtaaat gccaaagatg caaaacaaac ttaaaacatt tattttattg ttaagtaatg
    38581 ctataatata atgtgatttt aataatgata gtggaggttt aaatatgaga gtcgaggccc
    38641 ctataaaagt agatcgaaaa accaaaaaac ttgctaaaag agttgaaagt ggggaaatag
    38701 cagttataaa tcatatagac atagatgaag ttgctgcaaa ctctttagta gaagctaaaa
    38761 taaaacttgt cataaatgcg gctccttcta taagtggtag gtatcccaat aaaggtccag
    38821 ggatattaac tgaaaataat atactaataa ttgataatgt tggagaagag ttatttgaag
    38881 aattaaaaga aggagaaact atagaagttg tagatggaaa gatatataga aaaggaaaat
    38941 ttttaggtgc aggagaagtt ttagacaagt atgaggtttc acaccaaata aaggctgcct
    39001 atgagaattt agctgtagaa ttggatagat ttatagataa tactatagat tatgctaaaa
    39061 aagaaaaagg atttatactt ggagaagtag aaattccaaa agtgaaaact aattatgcta
    39121 ataaacatgt attgatagtt gtaagaggtc aggactacaa agaagattta agtactatgc
    39181 tttcttatat agaagaggta aagccagtat tggttggtgt tgatggagga gcagacgctt
    39241 taattgagtt tggatatact ccagatgtga ttgtaggtga tatggatagt gtaagtgatg
    39301 aagctttaaa aaaggctagt gaaatagtag tacatgctta tacagatgga agagcaccag
    39361 gtcttaagag ggttgaggaa ttaggcttag atgcagttgt atttcctgca ccaggaacta
    39421 gtgaagatat agctatgctt atagcctatg agtataaggc tgagttaata gtagcagttg
    39481 gtacacattc aaatatgatt gattttcttg aaaaaggaag aaaaggtatg gcaagtactt
    39541 ttttagttag actaaaaata ggttcaaagc ttatagatgc taaaggtgtt aatttgttat
    39601 acagaagtaa attaaaaata aagtacatat gggcattaat agcaacagca ttatttcctg
    39661 tgttggtagt tgcatcattg tcaccaggag ttcaacagtt catacaacta atgcaattaa
    39721 agtttagagt attattacag atgtaaattt taggaggata aatatgcata ttaatatgaa
    39781 atattatata gtcactatag gggctatatt tatagctttg ggtataggca tgttagtagg
    39841 atttaattta aataataatc aacaattaag tgaacaacaa gcaaacataa taaatgattt
    39901 ggatgataag tttaatatct taaaagaaaa aaatgataaa cttgacagtg acttagcaag
    39961 tgtaaataga gattatgaag aggcagttaa ttttataaat aaaaatgtag ataagatttt
    40021 agctggttcg ctgaatggta aaagtatagg aataatatct gctaatgaaa atgacgatta
    40081 tacaaaaaat atagaagaca taataaataa atctaatgga agcattgcat ttaatataat
    40141 attaaaagaa aacataacaa atccagaaaa gttaaaggaa atgtcaacta aactaggtac
    40201 agatgtaaaa aatgcaaatg atgcagttaa ttatataatt gacactctta aaaaggaaga
    40261 tgcaagtgac attttaacat atcttcaaga actagatgta ataaagttta attttattgg
    40321 agatacatat ctaaaatatg attccgttgt aatagctggt ggaaatgatg caaaagacag
    40381 tacaaaacag tttgaaaaaa tagaaaaatt tgtagtttca aaacttaaat cagagaataa
    40441 atatttagta gaagttcaaa atacaggagt taaaacttct tatgtagaac tatattctaa
    40501 aaacaaagtt gcaactatag acaatattga tgaaggtata ggaagtatat ctctagctat
    40561 tcttctacaa caaggtaata tagttggtaa ttttggtaga ttggatactg caacttcatt
    40621 gttgccatct attaaataga aataatttta aggagagaaa aaatggattc ttatataagt
    40681 ataataatac cagcttataa tgaagaaagt agaataaaat atacattaga aagcatattg
    40741 gacattaagc aaataaatga aataatagtt gtggatgatg gttcaattga caatactgct
    40801 aaggttgtat ctgagctaga aaatgaaaag attaaatttt ttaagttaga taaaaataga
    40861 ggtaaaggat atgctttaaa ttatggtatc aagttagcaa tgaaaaatgc agatattata
    40921 ggttttctgg atggagattt aggaagttct gctaaagaag ttgaaaaatt aatagtacct
    40981 atattaaatg gtgaggcgga tgttacaata gccaagtttc ctcctgcaaa gagaaaagga
    41041 ggtttgggat ttgtaaaagg tttagctaaa aattctgtgt ttgagatgac tggtgttgag
    41101 ttagatgcaa ctttatcagg tcaaagaata tttaaaagag aagttttaga aaagtttgat
    41161 gaaatacctt ttggatatgg agtagaagtt ggaatgacca ttgatatatt aaagtatgga
    41221 tttaaaatta aagaagtatt agtaaatatg actcataatg aaacaggaag aaatttaaaa
    41281 ggttttattc atagagggaa acagtattat cacataaaaa aggttttagg acaaaaaaag
    41341 aaagaatgga ggtaatatct tagtgaaaga ttatatactt tataccattt tattattaac
    41401 tggattattt ggaacctatg ctgtaattcc actatttaaa aatttattga taaatggaaa
    41461 tgtacttaga ccaaactata aaaaagatat gataccagta agtatgggaa ttgtattttt
    41521 gcctatgatt gtaatcaatg gaataatact tgctttcttt actacagaat ttaagaattt
    41581 agcgtatata tttatgttta tgtttggtat gatatccatg ttttttgcag ggatactaga
    41641 tgatgtcatt ggaaatagag atgtaagtgg tttaaagggg cattttaaaa gtttatttaa
    41701 aggaagtctt acaacaggag gttttaaagc tttatttggt ggatttgtag ggcttatagt
    41761 ttctgttgct atatcaaaag acataattga tataatagta aatacactaa taatagctct
    41821 atcaactaat ttaatgaatc ttttggattt aagaccagga agggcaataa aagcatattt
    41881 attcataatg gtaattatat ttttaacatt gacaggattt gttcaagttc ttccattact
    41941 tatagtacca aatgtacttg catactttaa ttatgattta aaagcaaggg ctatgatggg
    42001 agatactggt tcaaacgtcc ttggaatatc tattggaatg ctcatttctt ttgggtatcc
    42061 atttaacatt agattaggat ggttaatatt tgtagttatt atgcatatat tcactgagaa
    42121 atactcatta actaagataa tagaaaaaaa taaactatta aattttatag ataaattggg
    42181 aaggtagtat tatgataagc aaaagagtgg ggattgttga atcaatagta agtcaaactg
    42241 aaactctaga tgatataaga gtaaatataa atggagaaat acaaagggca tataattatc
    42301 ccaaaatatc tggaactata aatataggtg acgaagtggt tttaaataca acagcagtag
    42361 aactgagctt aggtacaggt ggataccatt ttgtaataac taatttaaat aatatagaat
    42421 ctactttaac tgaaggtgga catataatga aacttagata tacgcctctt caaataaaag
    42481 tggattctgt tgaggaacaa gaaagtattt atcatgataa atttgcgaat tttaaaggat
    42541 tagaaggtct ttctgttgta gtagggactc ttcatagtat gttaactcca tttgcagctt
    42601 catttaaaag aaataatcca aataaaaaat tagtgtatat aatgactgat ggagcatctc
    42661 ttccaattta tttaagtaaa aatgtggata ctttaaaaga aaaaaaatta atagatagta
    42721 caataactat aggaaatgcg tttggtggag attatgaatg tataaatata tatactgcat
    42781 taattacagc aaaagaaata ctaaaagcgg atgcagtatt tgtcagtatg ggacctggaa
    42841 ttgctgggac aggaacaaaa tatggattta cagggattga acaaggctct attcttgatg
    42901 ccgtaaaaaa acttgaagga agagcaattg caattccaag aattagtttt gctgacaaac
    42961 gagaaagaca tcaaggtatt tcacatcata gtatgactgt atttaaagaa attgtaaatg
    43021 taaatgtaga cataccaata actatatatg atgatgaaaa attgaacttt ataaaagagc
    43081 aaatcaattt aaatggttta gacaaaaagc ataatataat ttatatagat aataataaaa
    43141 cgaaagagga tttagactat tttaatctaa aagtaaagag tatgggaaga aattatgaac
    43201 aagatgaggc atttttcaaa gctgcaagca cagcagcata ttacttaatg gaggtttaag
    43261 atggtattag aagaaaaaac tattagtagt gatagggttt atacaggtaa agtaattact
    43321 ttaaaggttg atactgttga aattccaggg caaggatatc aaaaaaggga gttagtagaa
    43381 gttggtggag cagtaggaat agttgcaatc acagatgata ataaagttgt gttagttaag
    43441 caatttagaa aacctataga aaagccaatc tttgaaattc cagctggtaa actagaaaaa
    43501 aatgaaagtc caaaagaatg tgctgaaaga gaattaaaag aagaaactgg gtatagtgca
    43561 aaaaatatta agctaataca taaatttttc acttcagcag gtttttctaa tgagataatg
    43621 tttgtatatt tagcaacagg tcttactcca ggagagaata atttagatgc agatgagttt
    43681 ttagatgtct atgaaattga gcttgaagaa gcatataaca tggtattaaa aaatgacgtt
    43741 gaagatgcaa aaacatctat tggattatta ttagtaaaag atatgtttaa aaattaatat
    43801 ttataaaatg aataaccctt tgtcctaaag catactattt tataaaggac aagggggaat
    43861 taaattgaga agaacatata gaaaaaatga ttttagagaa ttaaatagac aaataattat
    43921 tataggattg ttgtttatga tgtctattgt tgttgggtct tacataaata aaatattgcc
    43981 aggttctagt aacaatatat taaacaatat aaatcctgct gtagagtatt ataatctaaa
    44041 tataagcata aaagatacag tgatacaaaa tttaaaatca gatgcaatct ttatgggctc
    44101 aatagctcta ttaagtctat ttgtagtaac aattccagca gtgttggtag cttttgtatt
    44161 aaaagggatg tcaattggtt atacaataaa tagctgtata ttggcattaa aatttaaaag
    44221 tataaaaatg attttaataa tattatttaa aaatttgatt attattccat gtgcaatcat
    44281 attagcatta attagtttaa gttattttaa agaaatggtt tatgaattta aaaagaaaaa
    44341 tagaaaaaat atgcaatttt taattaagag gtatatacta aatattataa ttataatagc
    44401 actatcattg gggttgcaat taatattaaa tactgcaagt attggtatta ttaagttcct
    44461 agctaaataa aggagtttat aatggatatt atagagggat atatagatta cataaaagat
    44521 aaaaaaaaat tatcagagaa tacagtggca tcatacttta tggatataaa aaaatatatg
    44581 gaatatataa atcaaaaaag cattaaacta gtagatatag tagaaaatga tattataagt
    44641 tacttaataa agttggaaaa agataatgta tcaatagcta caatagcgag gatgatatcc
    44701 tctataaaat cttttcatga ttatttattt ttaaatcata tatgtacaaa taatcctgca
    44761 aaggatataa aaaaacctaa aataaaaaaa gaaaatataa atatacttac agaagaagaa
    44821 attgaaagac tattaaattt tccaaagtta acaacgccta aattgattag ggacaaggct
    44881 atttttgaag tattatatgg tactggtata aaagtatctg aattagtaga gatgaatata
    44941 gaggatattg acctagatat tgattatata tattgtaatt catgttgtaa aaatcaaaga
    45001 gtgataccac tttgtgatat tacaaaactt tacttagaaa agtatctaaa agaagcaaga
    45061 cctaaaatgg ctgtagaagg tgaaaaatca ttattcgtaa gttcattagg tcaaaggttt
    45121 acacgacaag gtctttggaa agtcataaaa aaatattcta atctagccaa tatagataaa
    45181 aatataaatc ctacaatgct tagacattca tttgctattc atttgttaaa tgaaggtgct
    45241 aacattgctg ttgtaagtaa aattttagga aatgttaatt tatctagttt gcaagtatat
    45301 ttaaatcata tagataaaaa cgtgagaaga gaaataaagg agaaacatcc tagaaatgat
    45361 gttgatgtag aattacaaaa agcagaagct aaatagacta tatagcaaat tttataattt
    45421 agaaggagca tatttatatg agcagagtaa tttggattgt aattgatagt gttgggatag
    45481 gagcattacc tgatgctgaa aaatttggtg atagtaagga tgtaagtacc cttggaaata
    45541 tatttaagga atatccagat attcagattc ctaatatgag aaatttaggt ataggaaaca
    45601 tagatggtat agattttttt gaaagtataa aagaaccaat aggttgtttt ggaaagtgta
    45661 aggaaatgtc tcagggaaaa gatactacta caggtcattg ggaaatgact ggtataatag
    45721 ttgacaaacc atttaagaca tttgaacatg gattctctaa ggagataata gaagagtttg
    45781 agaaaaaaac tggaagaaaa gtagtaggaa ataaaccagc ttcaggaact gtaataatag
    45841 atgagtatgg agagcatcaa ataaaaactg gagatgtaat agtatataca tcagctgata
    45901 gtgtatttca gattgctgct aatgaagaag taattcccct agaagaactc tataatatgt
    45961 gcaaaatcgc tagggaaata atgatggggg ataatgcagt agctagagta attgctagac
    46021 catttatagg taagaaaaaa ggtgagtttg tgaggacttc aaatagaaga gattattcac
    46081 tagacccatt tgaaccaaca gttcttgata atataaaaga atcaggactt gatgttttag
    46141 cagttggaaa aatagaagat atttttaatg gaaaaggaat tacagatgct atccacacta
    46201 aaagcaatat ggatggagtg gatgaaactt taaattatat gaaacaagat aataaaggtc
    46261 taatatattc aaatctcgtt gattttgatt ctaaatatgg tcatagaaga gacccagaag
    46321 gatataagaa agctcttgaa gagtttgata gtagacttcc tgaaataatg gctaatatga
    46381 gagaagatga tattttaata atcaatgcag accatggaaa tgacccaaca tataaaggta
    46441 cagaccatac aagagaatat atacctgtta tgatttatgg caataagatt aaaaaaggtt
    46501 ttaatttagg agtaaaagat acttttgctg atattggagc aactgttgca gatatactaa
    46561 atgtaaagtt gcctaaacat gggtcaagct ttaaaggaga tttattttaa attataaaat
    46621 gataaaaact tagcttaata ggatggagag attggaatgt ttgaaaagat agcacaaagt
    46681 agtaaattta taaattctaa aagtaatata aaacctaaga ttggtttgat attaggttct
    46741 ggactaggtg atttagcaaa tgatatagaa gaccctgtca caattaaata tagtgaaatt
    46801 ccaaacttcc ctgtatcaac agtagcagga catgctggac aacttgtaat tggaaaactt
    46861 gaaggaaaag aagttattgc tatgcaaggt agatttcatt actatgaagg atattctcag
    46921 aaagaagcta cttttccagt aagggttatg aaagaattag gagtcgagat tcttatagta
    46981 actaacgctg ctggaggcgt aaataaagaa tttaaagcag gagatttgat gcttataaga
    47041 gaccatataa actttagtgg aagtaatcca ttagtaggaa aaaatgatga cagatttggt
    47101 gctagatttc cagatatgtc agatgcatat tcttctaaat atgtagatgt agttaaaaac
    47161 tgcgctaaag aatgtaatat agatgtcaaa gaaggcgttt atatgttttt tagtggtcca
    47221 aactatgaaa caccagcaga agtgagaatg gcacaaattt tgggagctga tgctgtaggt
    47281 atgtctactg ttccagaagt catagtggct tctcactcta atataggagt tattggtata
    47341 tcttgtataa caaatatggc tgctggcatc ttaaatcaac cactaagtca tgaggaagta
    47401 atagaaacta ctcaaaaagt taaatcagaa tttatgaatt tagttaaaac aacggttaaa
    47461 aatttataag ttaaagctta ttatagattt tttgaggaag tttataataa aatagttaat
    47521 gtttaatttg aaaagaatta ataaaaagct gtcttgatat agaaagttat ttctaataaa
    47581 ggacagtttt tttataatac tacaacattt gaaagtgttt taaagtttaa tatttattta
    47641 aattattata ggttagaatg gagatttcaa ttatgagaat gtatgatatt ataaaaaaaa
    47701 agagagataa cctagagctt agtaaaaaag agataaacta ctttatagaa aactattcaa
    47761 agggagatat acctgactat caagcttctg cactattaat gtcgatttat ttaaataaga
    47821 tgaataaaca ggaaactgta catcttacag aagcaatgat gaactctgga gacatgataa
    47881 atctatctga gatagatgga ataaaggtag ataagcatag tactggtggt gttggagata
    47941 agactaccat agctcttata cctttggttg cttcatgtgg agcaccagtt gcaaagatgt
    48001 caggtagagg tcttggtcat actggtggta ctattgataa actggagtct ataccaggtt
    48061 tttcgacaga aatggagata agtaaattta ttgattctgt aaataagtct aaaatagcag
    48121 tttgtggtca aagtgcaaag gtagcaattg cagataagaa aatatatgct cttagagatg
    48181 ttacagcaac tgttgataat atatcattga tatcatcaag tgtaatgtct aaaaagttag
    48241 cttcaggagc tgatgcaatt gtgctagatg taaaaactgg tgatggagca tttatgaaga
    48301 cattagaaga gtcttttgag ttagctaaat ctatggttga tataggtact ggtatgaata
    48361 gagatacaat aggtattgta acagatatgg atgaaccttt aggttttgca gtgggaaact
    48421 ctttagaagt tatagaggca attgagacat taaaaggaaa tggacctaaa gaccttgttg
    48481 agctatgcga agtattagga gcatatatgt tggttttatc aaagatagca catgattttg
    48541 aagatggtgt tgaaaaaata agagaatcaa taaaatctgg tactgctata caaaaactca
    48601 aagagtttat agagaatcaa ggtggtaata aagatgtagt agatgattat tctttattca
    48661 aaaaatcaaa gtataaatat ccagttaaat caactaaatc aggttatata agtaaaatta
    48721 aagctgaaga tgttggtgta tcggctatga ttcttggagc aggtagagaa actaaagatg
    48781 atattttaga tttatcagca gggataattt tagaaaagaa agtaggagat tatgtaaatg
    48841 aaggtgaagt tttagcttac atgtattata atgatgaaca aaagctttca ttggcaaagg
    48901 gaagatttat tgattcctac tctattgtag attcaaaaat agaaaaaaat aaattaatat
    48961 atggtattgt aactaaagaa gagattaaaa agttttagaa aattttagaa aagtgattat
    49021 aaaaggccta acatgtcaaa aataatgtta ggttttttat tttttgataa actataaatt
    49081 ataccaaaaa tatatatttt aaaacatttt ttacaatata aataagttta ttctacaaga
    49141 tgattgaaaa ttaaagtatc tagttttata atagaaaatg gataaatata cataaggagt
    49201 agattatatt atgaacttta aagaaaatag attgaaaata gcagtattaa taattgttat
    49261 tttgattatc ttagcaggta tatttgtgtt tatacaaata ggtccttatg ataaaaataa
    49321 caaaaaagat gtaattatcg acgttccaaa tggagcatct gttggaaaaa tatctgacat
    49381 attatatgaa aataaattaa taaagaatga actattattt aaacttttgg taaaggttag
    49441 caataaagct ccgtctataa aatcaggaac atacttactt aatcaatcgt attcaaacaa
    49501 tgatataata agtcttttag tttcaggtaa aatatatcag gatggtataa aagtgactat
    49561 tccagaggga gctacatcta aagaaattat agcaatgtta gtaagtaaaa atttaggaga
    49621 taaagctact tttgaaaatt taataaaaaa acctcaagaa ttttatgata aatttccata
    49681 tttgaaggaa gatggaataa cctctttaga agggttcttg tatccagaaa cttattattt
    49741 taattcaaag aaacaatcag aagaagatat tttaagcgaa atgttaaaag tatttgatag
    49801 taaatacacg gacaagttta aaaagaaaca aaaagaatta aatatgactc ttcaagaagt
    49861 aatggaaatg gcatcaataa ttgagaaaga agctgttctt gacaaagaca gacctataat
    49921 agcaagtgtg ttttataata gacttaaggt aggtatgcct cttcaatcag atgctacaat
    49981 acaatatata tttgaagaga gaaagaaaat tgtaacatat gatgatttaa aaattgattc
    50041 accatataat agttataaaa ataagggatt acctcctaca ccaatatcaa atcctggtat
    50101 aaaatctatt gaagcagcat tatatccaga gaaaacagac tatttatatt ttgtagctaa
    50161 gattgacggt ggaaataatt atagtacaaa ctatcaagac catttaaaat acgttaaaga
    50221 atataaagaa gcaagggata aacaatcaaa agatacaaaa gcaacaaata aagaaaatac
    50281 aaaaaaataa atcatgatta taaaaagtct aacagggtaa gaataatgtt gggctttttt
    50341 attgaaaatt gttattctta gatttataat aaagaaagtg taaatatata taacaatatg
    50401 aatttaaaaa ataataaatt aatataaaac ttgaatattt attattttag ggagtgtttt
    50461 tatgagtaat atagttaatg atttggttga agattatata agagtgacat taaaagaaaa
    50521 agaaggattt ttaaaagatt tagaaattta tgcagaggaa aatagtgttc ctataataca
    50581 taaagaagtt tcagatttat taaaagtctt gttaaaggtt caaaaaccaa agagaatttt
    50641 agaagtagga tgtgcaattg gttattcttc tatttttttt gcaactatta taggaaaaga
    50701 tgcagatata ataactgttg agagaaatga aaaaatgata gaaaaagcaa aagaaaacat
    50761 aaaattagct ggatttgaca ataacataac tatactagaa ggagatgcag aagaaaaact
    50821 tagtcaagtc caaggtgaat ttgaccttat atttatagat gcagccaaag gtcaatataa
    50881 gctatttttt gatttagtta tagataaatt aaaagatggg ggacttttag tatctgataa
    50941 tattttgtat aaaggtatgg ttgctcatga tgattttgtt gtaagaagaa aaaagactat
    51001 agttaaaaga atgagaaatt atttagatta tatatgtaat tgtgactatt taagcacatc
    51061 attggtacca ataggtgatg gtgtagcact aagttataaa gaaagtaaaa gaggtgatgt
    51121 agatggaatt aaataaagta gaacttttag ctccagcagg tgatttggag agattgaaaa
    51181 tagctataac atatggagca gatgccgttt atataggtgg agaaattttt ggaatgaggt
    51241 ctgcagcgaa gaattttagt aaggaagata tggcagaggg agtagctttt gcacatgaaa
    51301 gaggcaagaa agtattcgta acagtaaata taatacctca taatgaagat tttctacaat
    51361 tagaagacta tttgttggaa ctagaagaga taggaataga tgcagttata atagctgacc
    51421 caggagtgct tagtgtcatt aaaaaagtaa ttccgaatat ggaaatacat ttaagtacac
    51481 aagcaaatac aaccaattat ctaagtgcaa acttctggta cgagcatgga ataaaaagag
    51541 ttgtagtggc aagagaatta tcttttgatg aaatatctga gataagagca aaaacacctt
    51601 tagatatgga tatagaagcg tttatgcatg gtgctatgtg tatttcttat tctggcagat
    51661 gtttaataag caactatatg actggaagag atgcaaacaa aggttcttgt gctcaatctt
    51721 gtagatggca atatcatttg gtggaagaaa aaagacctgg tgagtatttt ccaatatacg
    51781 aagatgaaag gggtacattc ttctttaact caaaagattt atgtatgata gagtatatac
    51841 cagagttaat caaatctggt ataacaagtt taaaaataga aggtagaatg aagactgcat
    51901 actatgtagc tactgttgta agagcataca gaatggcaat agatgaattt tacagagacc
    51961 cagaaaactg gaagtttaat ccaatgtgga tggaagaact aaaaaaaggt agtcatagac
    52021 attttacatc aggtttttac ttgaataaac caacaacaga agaccaaaat tatcaatcag
    52081 catcatatgt tagaaactat gattttatag gtatagttag agaaacagaa gatgaagatg
    52141 gtcttattgt tgttgagcaa agaaataaaa tgtgtgttgg tgatgaaata gaagttatgg
    52201 gaccatataa agaaactatg tttactaaaa ttgaagaaat gtacaatgaa gaaggagaag
    52261 ctatagaatc agctcctcat cctagacaaa tagtgaagtt aaagctatca gtaaaagttg
    52321 gtaaagatta tatgcttaga aaagttatag aagaaaaggt tgaagaataa taaaaaattg
    52381 ataaaaatag tattagcccc ttagaaattg tcaataatga aattatctaa ggggtgattt
    52441 catgtcaaaa aagaagactc catttttgaa aaaagtggga aagagaagct ggtgtatatt
    52501 tactataatt ttaataattt atagtgtttt aatttatagg ctagttgata tacaagtatt
    52561 aaaaggtgat aaatacaaac aaagtgttga atcacaaagc gttgagaaag tcgagttaaa
    52621 tagtggaaga ggaataatct atgatagaaa caacaagaag cttacagata caagtaaatc
    52681 tcaggtatta attgttgaaa aagaaaaatt aaataataac tataaaattt tggagcttat
    52741 taagaaagct actaagatga atgatttaga tatatataaa gctgtacaag agcaattgac
    52801 acgccctata atacagattc agactaaaaa tatcgataag agtatgaaaa aagaacttga
    52861 gaaaaatgga ataatggtag aagaaaaaac tatgaggtac gcaaaagatg gtttattatc
    52921 acatacaata ggatatataa aagaagatga taaatcaggt caatcaggaa ttgaaaagag
    52981 tatggatagt gtacttagaa attcaaatga aaagtatata agtgctttta aagctggaga
    53041 tgcaggaaat gaaaaatctc taaacatact aaagggaagt gtaaaaactg ttgataataa
    53101 ggataaagat agacatctaa aaactactat tgattataac attcaaaaaa aattagaaca
    53161 aatactaaat aaagaagaaa atcctacagc agcaataatc tcggaagcat ctacaggtga
    53221 aattcttgca atgtgctcta gacctaattt tgaccaaaat gacatatcaa aaagtttaaa
    53281 aggaaaaaat ggggaatttg aaaatagagt tataaaagcg acatatccac cagggtctgt
    53341 atttaagatg gtagttttat tttctgcact tgaaaatggt gttatagatg agaactatac
    53401 ttacaactgt acaggtaaga ctaaagttgg gaatactaat gaaatactgc gatgtaataa
    53461 aagagatggt catggtttcc aaaacttaag acaagctttt tctaattcat gcaatcctgc
    53521 atttttagat atagctatga aacttggaaa agaaaagata ctcaaatctg ctgaaaaatt
    53581 acatttattt gaaaaggttg atattggtct tgatgaagaa aaaattagag aagctccaaa
    53641 aaacatatca ataagaaatt tagctatagg tcaagaaaat atagaattta caccacttca
    53701 aataaatcaa atgactcaaa taatagctaa taatggaaca ttcaaaccac tatacttata
    53761 taaaagtctt gtggacaata atatgaatac aataaaaact tataagtctt caaaaaaaga
    53821 agaacttatt tctccttatg tgtgtacaca agttaaagaa tatatgaagt ctgtatctag
    53881 gactggtaca gctaaagacc taaaagatat tgaaggtggt tgtggagtta aaactggtac
    53941 agctcaaagt agtttaaata aaaaagctat agaccacgga tggataacag gattttatcc
    54001 tgaagaaaga cctaagtatg taataactgt gttagtagaa ggaactcaaa aaggaaataa
    54061 atctgcaaca cctatattta aggaaatatg tgaaagtata aaataaatta tgtactataa
    54121 aatttaagga tatatcgtaa ctttgatttt agatagaaaa ttttgtctaa tgatgtacga
    54181 tatatccttt taaaatatag tattaacttt cttgaacaag ctctttttct agtttcttaa
    54241 gagctttttt ttcgattcta gatacatatg accttgatat atcgagtttt tgtgcaattt
    54301 ctctttgtgt cttatagcca taaggagtta acccatatct taactggaca atttctcttt
    54361 ctctaggagt aagaattttg tttagttgtt cgtaaagttt tccaacttga acttttagtt
    54421 caacttcatc aagaacatag ttagcctctg taccaagtat atctaaaaga cttatttcat
    54481 tacacactac tctttatatg ttattggtat tactggtctt catgtaattt caaatggacc
    54541 attaattcaa aagaatctag tttttgttct ttagacttat aataaactgc tttattaatt
    54601 acagatttta ggagtttatt ttttccaagg gaatctgaat catggtaaag tgataacaca
    54661 gttttaatat cttctattat tttagaattg tcttttttaa cagtactcaa tctatttttt
    54721 actgtcttaa ttgaatcttt aatttcttca gttcttgaac ttatattgtt ggacctttca
    54781 ataaatgtat cttcatcata tattcctcgt tctagtaaat catataactt atttttttgc
    54841 ttgcctaatt cttttaattc agtttctaag ccctttaaga ctcgtttttg aaattctata
    54901 ttactatctt tattattttt atctaagtct atatcagatg cttttaattg atattttttt
    54961 acagtgtctt ccaaagattt taaaatggca gcttcaataa attcaaatcg agaactttta
    55021 ttgcaaccag gatgataaca aattatatag tcatggtctg catatggtct atatactaat
    55081 ggtctaccac aatttttgca aatcactatt cctgcaagtg gattttttat ttgattacca
    55141 tagctgacat gaccattttt tttgagtata ttttgagctt ttttccatgt tatttcactt
    55201 attaaaggtt catgctttcc ttttgcctca atccattcat ctttaggtct tagtttaact
    55261 gtttttattt tatttggatt tttagatttt ttgtagtcct ttttttgcca ctgaatgtag
    55321 ccacaatata ccttattttt tattatattt gtaattgcag aattgtacca attagcacct
    55381 gtagcagttt taatgcctaa gttatttagg tattttgata ttttactaca acccatatct
    55441 tcattaatat ataagtcaaa gatagtccta actacatcag catctttatt tggtacaagt
    55501 attctttctt ttctaccagt tgttacagca tcatatccaa atggagcaga ggttcctatg
    55561 aaattccctt cttcaactga ttttattcta cctctttgca ttcttcttga tataagtttt
    55621 aattcttttc ttgccataaa tgcttcaaat tctgaatact cctcatcaaa ttcatctgtt
    55681 aggtcgtatg tttttctagg tgtgatgatt ttggtcttac tttctttgaa tgtttctaat
    55741 atgatacctt ggtctttcat gtctccacga ccaagtctgt ctaagtccat tactaagact
    55801 gcatcatatt tattttcttc aacttctttt agaagttcaa gcattttggg tctatgtatt
    55861 atactttcac cagaaactaa ttcttctttt atctcaatta catctaagtt ttgttctttt
    55921 gctagtttta gtagggttga tttatgtcta cttaaagttt caaattcgcc ttgtttttct
    55981 gcctcttcat cagcacggga ttttcttaag tatatggcaa cactcataat aagtaatcac
    56041 actccttatg cactattata tagtaaatca atagagttta aaatatagaa aataagcatg
    56101 tcaaaagtta atttaacttt caacatactt attttctata atattaatgc cttataatcc
    56161 tttaatatca tttagattag tttttgcata ttcattatcc gggttaagtt caagcgcctt
    56221 attgtaagat tctctagctt tattaaattc tgatttactc ataaaaataa cacctcttaa
    56281 attgtaagca tcactagcat ctattttata agcttcatta tttttatcta gatattctaa
    56341 gtatttatca attgacttta aagcctcatc atatcgttgt aactctatat aaatatatga
    56401 ttgtgtataa tatgcaagtg gatttttatc atcaatttct atagcttttt tgatatcaat
    56461 agcagcttta ttataatcct tatctttatc tttttctgtt tctgacctag cgattttgac
    56521 ataattagag ctaagagctc ttttaaagtc tttatgccat aataatttat attcattatc
    56581 ttcgattata aaatatctat caaaatttgc agtatcttct ttattttcag tgatatactt
    56641 tatagtatca gtttctttta ttttaacaag atttgtgtac tctttattag aatatttgta
    56701 tttctctact ttattttctt caccaagttt ataatctttt agggtttgaa gtttaaataa
    56761 agtatcttga tattcttcaa atttttctag actgacactt tccttactgt ctttacttaa
    56821 taaattatat gctacttcgt agtctttgat ttctatacta tcaaggtact ttttagctac
    56881 ttctgtagca ctttcttttg gagcacatcc aaccattgat atcataatta aaaatgatac
    56941 taatattgct gttatttttt tactgattat cataatataa tcccccttat attgtctctc
    57001 attaatttta ttttatcacc atattctacc aaagtcatta atttaagagt gatatttttc
    57061 attaatatta tattaagtaa taataacctt ttaaatttat ggtaatattt tcctgaaaag
    57121 tattatataa tttaggtgaa aatatttaag agaaggagat attatgaaaa ttaaaaaatt
    57181 attaacaata gggttatctt tatctatatt tattgctagt tgccctatat ctgcaaatgc
    57241 tcttgataaa attgaatcaa ttaaaggtgc agataaatac gaaactgctg gtataattgc
    57301 agacaaacaa aactatacta cagctatatt aattaatgca gacagtacaa tggctgatgg
    57361 attaagtgca agtggacttg caggagctat aaacgctcca attcttttga ctaagaaaaa
    57421 taacatacca aatgctacac ttaaaagatt agaaaaggca aaaaaagtat atataattgg
    57481 aggagaaaac tctattgata aatatactga aactgttcta aaaggcaaag gaatagagat
    57541 taaaagactt caaggtagtg atagaattaa gacaagctat aatgtcgcaa aagaaataaa
    57601 ctcaattaac aaagtaaata aagtcatatt gactaatgct tttaaaggag agcctgatgc
    57661 aatgagtgtt gcacctgtag cagttagaga taaagcagct atagtattaa ctgatggaaa
    57721 aagtgttcca tttaatacaa ctggtgtaga aagttatgta ataggtggta cttcatcaat
    57781 gaatgacaaa atagttaagg atactaattc aactagatta ggtgggacag atagatatga
    57841 tactaacaaa aagataataa ataaatttta tagtggagta aaagaatttt atatagcaag
    57901 tggtactgat ttagtgtatg ctcttgttgg ttctaccgtt gctaaaaata atgctattgt
    57961 gttagttgat aatgatagta ataaaagtgt attgaaaagt acaattaaat taactgctat
    58021 aggaaatttg agtgatagta tattacagca gtgtttaaat gtaacaaaaa atataggaga
    58081 ttctaatact ggaagagaat atacagtaga agatgctgct aatgcagtga aaaaactatt
    58141 aggtgtgaag aaattttatt acgaacctaa ttattcagaa gatgaagatt taatatttct
    58201 actagataaa aattttgatt tttcaggaaa agagtactat gtatttgctt acattaaaca
    58261 gggtgcagag ggtgatctta gatactgtgt agctaaaaat gatatgagca aagtttatac
    58321 atatgatgtt aatggtaata tgaaagtatg taatccagat gattataaaa ataaaggaag
    58381 tataacagag gaacaagcaa aacagatagc attaaaagaa tgtgctaaga gacataaagt
    58441 cagtatcaat aacttagtag ttgatatgat agattttaga gatgatatat atagtggtaa
    58501 tgtctatgct gttaaaatca attcaaaaaa tagtaatggt acttttggtt ggttttttat
    58561 agatatagaa actgggaaaa tttataatta aaattagaac ttttaaacaa gtgtttttaa
    58621 ttatataatt taccataata tgttataata tttttagcaa gaagatttaa cttacaatct
    58681 atagagtgga gttcatgtac aaaagattat cctcccaacg attcgaaggg aggtgagttc
    58741 atggataact ttttgtttaa tgttttagct agtttaacag ctagtgtggt agtttactta
    58801 atcagtaaac tatttaaaaa agcaaaaagc cactctcgca caaagagtga cttacgagtt
    58861 gaatttaaat ttatatttaa atccaaaaaa taaactctgt ttatgatgaa ctccactcta
    58921 acgcaaaata gattgtagtt cttcttgctt ttattatacc acaaaacatt ataaataaaa
    58981 ctgttgttta taaaaaaatg caaagtaaaa ttttttataa acaatgataa aaattttatt
    59041 atagagctat taacttatta aatatctgta aatgagcaga tatttaataa gttaatattt
    59101 attgtttaca taaaatattt ggtaaaaata agtaagtttt atatgttata atagttgtag
    59161 caagaataat aatctaaagt ggcaagcatg tcagctggtg ttatatcagt ttatatttat
    59221 gataaaataa aaatctccca aacgccaata agaatgattt aaaaaaataa tattttcact
    59281 taaaaataat cactctttat aggagtaaat tattttcttg attttattat actacaaatt
    59341 ggtacagata tttaaaaata atatattcat aatattataa atagttttgc agtgagcgat
    59401 atttttgata aaatagggct taacagttga aacataaggc attgagggta tatgataaat
    59461 attatcattt gcactactcg tggttcactg caaatttgag agaattgtat agatgtaagt
    59521 gttggaaata ctcaatttat tttggggttt tatattaact aagtggtatg taaagtcaat
    59581 taaattatta tattttaatg ctctttttaa tcgttttata ttaactaagt ggtatgtaaa
    59641 ggcagagttg atagtactat taaaagaaga aaagttaagg ttttatatta actaagtggt
    59701 atgtaaagct ataactttta ttaatttttg tttcataatc tttcgtttta tattaactaa
    59761 gtggtatgta aagttaatct ttaaaattaa atataaaaat aagctagaca tgttttatat
    59821 taactaagtg gtatgtaaag ttaataaaac tgatagtaaa actactaata ataaaggttt
    59881 tatattaact aagaggtatg taaagacttt taaaaattat ttagcgttat attgctgcat
    59941 aaaagtttta tattaactaa gtggtatgta aagacagata taatatcaaa ataaggttag
    60001 gacttttaaa agcatagcca tatcagtaaa aatttaatta tcatttaaaa aataaatttt
    60061 tatttaaaga atacacataa atatttccag actcaactct cttaaactat tttcatatct
    60121 tttagtagat acctttgttg ttttttaacc tttagcaact tgttcttgag tgaacctctt
    60181 attttttcta agttatttca agcttttcaa aaaattctct atttatattc atcacacata
    60241 taatacaatt aattcagttt taattgccaa tatttagttt ttctgtatct gataagccaa
    60301 gaatataatc agtatataaa ccaaaaattt tagcaaatat tattaaccca tcgtctctta
    60361 ttggtctctc accagactct attctattca taacacttgt atttatattt gttttttcaa
    60421 gcaattcttt ttgagaacta ttcatatttt ccctagtata tttaatcctt tgatttacat
    60481 ccatacataa ttatctcgaa aagtttctgc tttggaaata ttgttattga aatatagaaa
    60541 ttaatgtgaa tatatgaaaa agatacacta tgattttata aaaaagaaga catacataaa
    60601 atttatactt acaaagtatt gcaaaagagt taggttttaa aaatgcatca acttatttta
    60661 agtacaggaa agggtaatat tcaattagag ttgatatatt acctataaac tatctaagat
    60721 acttgattat gatatagaaa atttaattaa gaggatgata aggatgaata atttacaagt
    60781 aatataaaga aataataaga gaattttaaa tacatagcaa ctagcagata tatatgaaaa
    60841 tgatgtaaac aatatataaa ctaacttcaa tagaaataaa gagaatgtaa attatgtttt
    60901 attacaattc gagtatttga aagaatttaa gaactaatct attaatagtc agttgatttc
    60961 aaaacattct agtcaattat acatttggac cgaaagatgt gcaaatagac actgcaaaat
    61021 attagatatt gataaaactt gggaacaatt tgacaattta gagaaaatat atttcaagat
    61081 taagcgagag aaactaagct gtatagaaga tgtattaata gaaaatttaa tatttaagga
    61141 tacaaattaa tcaagcaata atatggcatt agaggcaaaa cagaagttaa aacaataaaa
    61201 gatgttgtta tattaaatat aacacattgg aaaaaagaaa caagtctatt aacagttaaa
    61261 atagctagaa gtcaaggtga tttaagttat gtaaaatatt ttgctaatga gagctaagag
    61321 cttcttaaca agagttttgg tgtgtctctt gaaacaaggt taacaattaa taaaagacga
    61381 atggcagaag aaggcgtatg taagtttaaa agagataagt taaacaaact agatattata
    61441 taagagaata agaaacttat agaagaatat gttacttttg taaaggattt ggctttaaaa
    61501 tatagaatat aaagtgattt taagtaaaaa ttgtaacaat taaataagta taagacaagt
    61561 ttatgagttc atattttata acaaggggtg atgttatgaa aatactacaa caatttaaac
    61621 catacaaata tgataaagaa aaaaatatag aatatgatga aaaaattata gctaatcaaa
    61681 acacagaagt ttatatagta tatccacgta tatctgatga agaaaatagg agaagatggg
    61741 aagagttcaa tgaggtagct aaagaagtag ctattaatat agctatgaag aaagttgaga
    61801 cagtagaaag ttaagagaat agagaagttg ctaatactta gcactttctc atagaagaaa
    61861 attggacaac tatttttaaa taattaggaa taaaaaagtt aaatcatatt tgaaaaaggc
    61921 gataaaattg ttgagtattg ttattagtaa taagaatgta ttaaaagaaa ttataagttt
    61981 ttagtaaata tagtatttaa gaatattaaa actggtaaaa aatatcattt agactattaa
    62041 ataaaaaagt gctggtcaaa gtaagcaaca caataaataa aaaaacttat agaaattata
    62101 agataaaaag atgagatttg aaatggttga agttaatata aaaattaaag gtgaagtaag
    62161 tgaaataatt gactcaatta gaggtatatt taatagcttt gatgaagagt taatattaga
    62221 tataaaatca gagtaagaat ataaaggtag atacgtagaa agttataagt aattcaagac
    62281 ttaaattaat ttctagtttt tttaatgcaa aaatttaata aatttcaaaa tataataatt
    62341 ctgacatcta aaaagagcta ttaaaaatga ataatattga ctattaagat atgaatagtg
    62401 tacatatatt aaattaagat atccagtagg ttaattttat ataatgatgg ggctcaaatt
    62461 gaagaggcga tataaaaatg tattaatata tataaatata agaactataa taaatattaa
    62521 ctgtaaaatt aaatttatag agttatattt aacatttaat gaactgaaaa ataagttagc
    62581 aaataatgaa aaaacaacag taataaatga gaataacaaa gcattttcag gattagtgga
    62641 tttttctaat tgagctttaa tcctagtttg ttcaatttcg atatttctaa tattattagt
    62701 attatcaatt tatttgtaat aattatcagt ttttgcgaaa tatttttgat aatttataga
    62761 actttatata ttttccttga agtatttttc gcccttattg tttggtttcc aattttaaaa
    62821 ctcataaact cccaataaat tcatgtataa tataccttaa tttataatat atttaagagt
    62881 ttatttcagt aatttttcga acgattttga tatatttcat ttatagtttt caaaaactta
    62941 tacaaaaaag agtgtttcat ttttctaaac actcttttta taagaatttg aataataatt
    63001 tttttaaaat tgataatatg gttatttctt tttcaagttt atagtttcct catttccatt
    63061 ccaagatata attagcttgt aactagattc tctatttgaa taaagacctg gtctttgtat
    63121 ttttattgct ttttcttgac ctgcttctaa aatttcattt tttacaacta caactgcatc
    63181 ttcaccatct ataaattgat aggaataatt aaatttttgt tcaactacat ctttactatt
    63241 tttatatttt atttctaatt ttgagtgtcc ttcagtagtt acaaatttag ctttccaatt
    63301 ttctgattct ccaataaaga catttttatc attttttata ttaagtatag ctatcacaga
    63361 gattattaaa actataagaa tacctataaa aaattttttc ctcatatcaa tccctccttt
    63421 gaataattat aacatgagaa tagttattca atactaattt taaaaatatt gtggatttat
    63481 attctattac aatagaatgt ctgttataac aaataaaaag tagggattaa tatgaattat
    63541 aggttaaaaa aatctgtaac aactatttta tctttactca taatgacaat actattacca
    63601 acaaatgcaa gtgctagtaa ggtagaagat tcatctatga aagtaatgta ttcagagaaa
    63661 caagtaacag acatggacaa attatacgat atggctaaaa atggaattac tgatgttaaa
    63721 agttacaatg aaaaaggtat aatcaaaaat gcaagaacag gagagtccat atacgttgat
    63781 tatatatcaa caattcaatt attagaagtt aaacaatcta aaaatttaac atcaaagaca
    63841 tattctaaga cagttttttt gatactaata caataaagcc tcttagaaaa gcaagtatat
    63901 cagaagatgg atgggataaa actggtggtg taaaagtatc tggtacagtt acatatacaa
    63961 tatcaaaagg agatggagca tttcaatata tttccgttag taaagtttct ggaaactggt
    64021 ctattgcaga cggccagatt cgtgtaacaa atagaagggt gcatataaat caaactggat
    64081 ttatttctaa tgggctggaa ttaagcagca acaaaagaaa gagccaacat caaattcttt
    64141 ctcatataat gcaccttcta gttggaaacc agtaggtaga gattcagttc aatacaattg
    64201 tgggtttgaa ttaattgcaa cattagtaag agaaggaagt tcttgggcat tcaatttcat
    64261 tgttcaacct taaaatattt taagtgaatt ttattaaaat caaagatatc atatacttta
    64321 aaattagaga atgtaaatta atttgtgctt ttaaagataa ttcctacgtt atagtaacaa
    64381 ttgcttattt attattaata tttcttaata tatgaatttt attttaacaa attataaaaa
    64441 atgtatattg agatgttttt aaatattttt ggaaattata tatattataa caattatagc
    64501 aaatttttag ggtataattt ttaaaattat attctactat caaaagatat gaataaatga
    64561 ttgtatatat tatatcaatt tttatatttc atagtccatt ttttcatcac attttcgctt
    64621 gtcaagaata atatctttaa gagtgaagcg tttgatgtaa atctggactt tgtttttgag
    64681 acatttttga aatatttatt aaatccttcg attatacttg taatatatat tatagatatt
    64741 acttatttta gtaaaactaa aggctgatgc tacaacattc cagttatttc caaacatttt
    64801 aatttctgaa gtatactgtt tacattattt ttaatctatt ttatctaaag tcgataaggc
    64861 tttttattca ttaactgacc tatatacaga tttaaaatca cttattaatt cttttgagtc
    64921 cttgtatgaa acatatttaa agtatttctt atctaatgta ttaaacattt ttgtattaca
    64981 gaatgaggat aacttgtagc tattgtctct ttgaaataag tcatctgtgt ttactcctaa
    65041 aactacttat atctgtagat tttataagtt ctccatctta tataatttct ttgattaatt
    65101 attttcttaa attattcata aaaaaatctc cgttacgata tttgattata tttaaatcat
    65161 tgccataaag aagactttta ttaactttga aaaacaaatt attttacatt actggtgatt
    65221 agttgctacc ttcttttgat attaattcta ttagatttta tatagttata tatctctttc
    65281 taactaagta atataatatt actgttatag tagctactaa tattattgct attattgtaa
    65341 tatctaatct ttttgtaaat aatcctattg ctatatattc aaaacctgtt acatatcgat
    65401 aaagtacttc tagtttaata gttctttttc tatctatatt tccatatttt gattctaatt
    65461 tattaaaata tttttcatta caaaaaccaa ttttaatttc aattaaagat attattgtag
    65521 ttaatattat aattcccaat cccataagta taagataaat gttcctaaaa ttcatagaag
    65581 atacctcctt tatattataa tcatcaactc atgttgtatt aattttccta atcaaagtat
    65641 aacagtaaca caagtataaa gagtatctaa aatattacaa atattaaatg agaaaaagat
    65701 ggtaagttaa ccccaccatc ttatttttta tctactaatg aatgatgcta caaaagttag
    65761 tataaaaaat gaaacaaaca atataatgaa cttgtgtaat ttacttagtt ggaatgcttt
    65821 attacaaaat aataaaatta atgctgaaac aattgcaaaa agtagatatt ttataatcat
    65881 tttatcacct attgatttct acagattgta agtagtattt ggttacacaa gcacctcctt
    65941 tattataacg tattttttaa atttaaagat ttttccagat gttatatttg actcaaggta
    66001 cattgtaatt actctaacta taacagtggc aagtactttc ctataccagg aatagcacca
    66061 gccaaaagtc ctgaaattcc tataccagca tcagttaaag ttaatgcaac tcctttagaa
    66121 agatataaat taaaacctat tctagcccaa accattttat ttatttcagc ttttctataa
    66181 tataattcaa gtagtgtcaa tatcgttctt attaaggttt ttaattagct tatatattgt
    66241 tattgtataa tataattatt aaaaattaac tatattaaat attaataaaa aatatagtaa
    66301 aacttaataa tacatacaat aaaacttaat ataaattaag tatatgaaat aaatatcctg
    66361 tatttaagct tatagattat aatgaaatat aatacatatt ataataataa aacgaactaa
    66421 aattatcaca ctaaagcata aaacatgctc taatcatgtt agataaattt ttgaatatat
    66481 aatccaaaag tactctctaa agtagagtac ttctttttta ttaattattt ttatatagaa
    66541 taaattggaa tttatattta ttccaatcta attgattaca tacacttatt gttataaagt
    66601 ttagttatac ataaattggt aagaggtgta aactaatgaa gattaataaa ttaccacatg
    66661 cagaactaaa actaatgaag tatatttggg gagtagatga tgtattagcc tcaagagata
    66721 tcatagaaga catgaagttg aaatacgatt ggaaaaagag cacaacattg acatttttaa
    66781 aaaatttagt agataagggc tttttaacta ctgataaggt agatagatgt acgcattata
    66841 ctatagctat aaaagagaaa gattacttaa aagttgagac aaagagtttt tttagtttta
    66901 tgcataacaa ttcatttaag agttttattt cagcactaca tgatgatgaa gttttagata
    66961 gtaagagttt ggacaaatta gaagaatact ttaaaaattt gaaagaagga gatattgatg
    67021 actaataaag ttatcagtat ctttttagtt tgagacaatt gagagtagcg ttttgattta
    67081 atgttagtgt tatgtgatgg tagaacatta tataaagaaa agtgcttatt tccttagtat
    67141 ctgatagtaa aaaaatatat agaaaataat accgattaaa atttaaagaa agatatgaaa
    67201 tactacaata gcttaaatca tgtaaatatg ataaagaaat tgaaattata aaaggaatat
    67261 aattttataa gaaatagttg acagataaat taccttacta tattattgta ttaataaaat
    67321 aatacaataa tatagtaagg aggtaataaa tgaaatctag aaaacataat attacaaaag
    67381 gattatttat agtttacata attattttaa catggataat actattcaag ttgcaatttg
    67441 atatctcatc ccttgaaacc atgaatctta gaagcataaa cttagtacct tttgctgggt
    67501 cacttataat taataataga gtagatatat cagagattat attaaatgtg gttatatttg
    67561 taccatttgg gatatatgtg tgtatgctaa aagaagaatg gagctttata aaaaaagtta
    67621 tacctatttt tataactagt ttggcatttg aaacacttca atatatattt gcactaggtg
    67681 caagtgatat aacggatttg ataggaaaca cactaggagg aatcatagga atagctgttt
    67741 ttatgctatt atcgaaaata tttaagaata ataccataaa aattatcaat gtattggcat
    67801 tgattgtgac aattattgtt gtattatttt taggattagt tatttttgca aacttataga
    67861 aataagtata tatgtttagc ttaaaataaa acgtaagata caattacata taaaattatt
    67921 tacacataaa aagcacctat acaggtgctt tcctaaatta ttaaagaatt attgtatctt
    67981 gaaactcttg tatgttcaat tcttgatttt ctcttgtttt ttctaataaa tctaacgcac
    68041 aatttataca aactttaatt tctgcattgg tatttttctc ataataagtt atatatttat
    68101 ttctatattt atctatttct tttccacaac gactacacat tactattacg ctcatatctt
    68161 agttcctcca tctctaatta ttcttaatat attcaatagt atcacttttc tgaaaataat
    68221 gattgttaaa actgtatcaa atttagattt actttttatt ataatgcatt ttaataaaaa
    68281 aataaaggtt atgggtaaaa tatttataga aaaaagtata ttattgaata gattataaaa
    68341 ttttattatt ttttagcagt gttaaagaca cattaatatc tataaagtga caaaataaaa
    68401 aatactattt aaatagatat taaaaaattg ataccaagta tttgtttgct atatgaataa
    68461 caatttattt aggaacttta ctttaacact gtataataat aaagtaattg ctaaaaacgt
    68521 ttgatgattt ggatgtattt ttagaaatta gaaaaatata tacttactga ctaatgataa
    68581 tcttatatgt attttagttt gagtgattta agaaaagtgt tttgaatggg gattatttta
    68641 tagagtaaat aaatatataa tagtagaaaa ttacatataa agagtagtgt ttatttcatt
    68701 accttcttta tctgttccga tagggtcttg tagagatact tgagttttat tttttttgtt
    68761 agatctaata ttcattaaaa tctcattttc aatacatcta gaagcatatg ttgctaatcg
    68821 agttccttta tctatgttat aagtttctat agctttgatt aatcctattg tacctatgga
    68881 tattaaatca tcctgatctt ccgttgaatt attatatttc tttgctatat aagctactaa
    68941 tctcatgttt ctttcaatta atgtatcttt tgcactttta tcgttttcta ttttaaattt
    69001 agttaaatac tcaatctctt cttcaggggt taagggtttt tcaaaagatt taagagctgc
    69061 caataggtca cccccttttc aacggtcact ttaaattata tgaaggagac ttatccaagt
    69121 tgactgttat ctaataaaat aatatgcata tttttagaat ttaaaacata tatttgcaaa
    69181 cttttgaatg gaatatgaca taaagagtgg gaatttaaat ttaagttttt gttgtatata
    69241 tatgaaacaa ggcgaagaaa ttattgattt ataaagtata aattagaatt gaggtgtcaa
    69301 taaatataaa aggaaatagt atttatatat gttttggtgt tgaagtaaaa gattaatgca
    69361 aagcattaga gtctataaaa atatgaatat aggaggtgta attttacaat acttaaaaaa
    69421 gtaaatgtaa ttaattgttt gtataaagtt gattacaagc aaaagtatca gtcatagtta
    69481 atactgttaa ggatgaagga ggtgtgttaa tttatatatg tatgggaaga aattttgatt
    69541 acaatgaaaa aacttacaaa agatatttac gaaaaaactt atagttaaat gtttatatat
    69601 aaaatattat ttaggggttg tttttattat tgaaaataag aaagagtggt tttatatcaa
    69661 ttgaatgtat aataagtatt gctatattat atgtggctgt ttatttagtt tctacatcat
    69721 tgtataattg ttatagtttt atcagtagaa atatatctaa cagagaaatg ttaagtacag
    69781 caaaaaaata tatagaagat gagaagtata gaatacaaaa tagtaagtat gagttaattg
    69841 aagataagat agaaaaaaat tacataaatg gatatgaaat taacagtaga atagagcaaa
    69901 ttttagatta ttatcaatgc tatgaaataa atatagagat aaaaaatgaa tttaaaaaac
    69961 tgaggtttaa tagctatgtt actagaaaat aaaggctcta tattaataat aacattgata
    70021 atattttcta ttataagtac tgtgtgcatt atgtgtatag gtttaattta tacacataat
    70081 aatatgtttg agttaggata caaggacatt caactaaaag aaatttcttt aagtggaata
    70141 gaaatatcag taagtaatgt actttcttgt gttgaggaag ctattgatgt atctaataat
    70201 gaagacgaat ttagagaata tttcttagga aataatatga ttgaatgtat aaaaaaaata
    70261 aaagatacat cttatagtag tttagaagaa ctttctttaa aagtagaaaa taatactatt
    70321 tatgacagag gagatttttt tgaatttgat atagaaagta atgttagaga aaaagaattt
    70381 ttaaaagcaa taaaagtaag agtgaaaatc aaaaatccat ggacaggaat tgatattgaa
    70441 gattatatgg ataaatctaa taacaataaa attgatgaca aaacattcaa taattataaa
    70501 gcatctgaaa ataatgaaat tctaaatcaa tttaaaaatg aaagtgaaaa tataaggaat
    70561 caagaggttg ttgaatttac agaagaagaa tatgaagaag aacttaaaca aaacataatt
    70621 gaaaatataa agaagaattt taatgaaaaa aacctagtac aggtatataa gtataggggt
    70681 gtataacttt gaaaaaagaa ggaatgtgac tgtaatagaa ttaatagtat ctatcagtat
    70741 aatactcttg atagttacat tatcttttcc aaaagataat cttgaaaatc ataaaataaa
    70801 tttatttgca cgtcaacttt gttcagatat aaggtatgtt aggcgaatta atatgtttag
    70861 caactacaat acatatatat attatataaa tcaaggtaaa cacgaaggtt atgtattgag
    70921 aaaagatggt aaaaacatta aatcaataat gctacctaaa aatgcaaaaa tagctaggag
    70981 tattgaaata ataaagttta aatctgatgg gtcgcctcaa aaggcgtcta caatagaggt
    71041 atataataat agattaagaa aaactataac aataacacct gtaagtggaa gagtacttct
    71101 gaaagaggga aaatatgaaa cataaatatg gttacttgct tttggaaagt gtcgtatcat
    71161 tgtcttcaat ggtgataatt atactagttt tatattctat atttttgtct acaataaact
    71221 taaagttaaa agtagaagat aagatagaac tacaacaaca aagtcttgaa atcataaaat
    71281 ctatggaagg aattattagc aattctatgg gaataatgaa tgtatctaat tatgaagaaa
    71341 catttaaaaa gacaacatct ataaaatgta gatatttaga tgaaaataat aatgaagaag
    71401 gcataagtaa taaagaaatt atattgaatg aaagacgaaa taagttattt gtaaattctt
    71461 taaatggcga aagtagtcaa gcaggtggtt atgaaattgg agattatgta gatgaaatgt
    71521 atgtatcaat tactaataat ggtcaatatg ttaatattaa attgaaatta tcaaaacgta
    71581 gtcaaaaata tgagactgat ttcaaaataa aagtatggaa ttttagtgaa agtatataaa
    71641 aatacataaa tttaagagaa agaaatgaca tcaataagtc atataaaata taattattga
    71701 gaactatata actaaataat atcaatatgt aaagtgtata gattaagaat atagaggata
    71761 ataataaaaa tatagaataa gtaatttgcc aaatacttgt ttatattgta taacttatga
    71821 tattatgata ttagtaaaaa tttgtaatcc tgacttgaca gaattcaagt aagagatata
    71881 attttaaagg catagtaatg taaaatttac taaaaaataa gaaatttatt ttaatatgga
    71941 ggaacaaaaa atggtatcag caggtgattt tagaaaaggt gttacatttg aaaaagatgg
    72001 acaaccatgt ttagtagttg attttcaaca cgttaagcca ggtaaaggag ctgctttcgt
    72061 tagaactaaa tacaaaaact taaaaacagg agctataaga gaagaaagtt tcaatccaag
    72121 tgaaaaattc cctaaagctg ttatagatac aagacaaatg caatatctat acaatgatgg
    72181 tgagttatat tattttatgg atcaagaaaa ttttgaacaa ataccattaa actatgagca
    72241 agttgaagat gcaattaagt tcttaaaaga aaatgaagtt gctacaataa gattttacca
    72301 aggacaacca ttccaagtgg aagcgccaaa ctttgcagag ctagaagtta cagatacaga
    72361 gccaggtata aaaggtgata cagcaagtaa tgtaactaaa gcagctacag ttgaaactgg
    72421 agcagttgtt caagttccat tatttataaa tactggagat aaagtaaaga tagatactag
    72481 aacaggtgaa tatttatcaa gagtataaaa atttatgtat ataaaagctt atatgtctta
    72541 ataatataag atatatgagc ttttagttta tatataaaaa agaaagcgag gggtgttaca
    72601 tgaaacattt atatgaagaa gttgcatact taaaaggcct agcagaagga ctagaaataa
    72661 gtgctgaaag taaagaaggg aaaatgatac ataaaatagt tgatgcatta gaagtatttg
    72721 cagatgctat tgtaacattg gatgaagaac aagaagaact tcaagatttt gttgaatcta
    72781 tagatgaaga tttagcagat ttagaagaag atattgctga catggaagaa gatctttatg
    72841 aagaagatga cgatgaggat gatgaggact tcagctatat agaaatggaa tgcccaaatt
    72901 gtggagagtt agtagaaata gacgaagatt tgttatatga tgatgaagta gatgttgttt
    72961 gtcctgattg taaggctgtg atattatcat cagaagatga ttgtgatgat gattgtacat
    73021 gtggtggttg ttcaagttgt gatgatagag agtaaaaatt cataagaatt aaaactgcct
    73081 atgatgccta tgagatattt tgcttcatag gtagttttat ttttatgagg aagggtatta
    73141 tgtattttgg ttttgcaata cttggacaaa aatagtacac tagaatttat agaataggat
    73201 tttggaggga tgtaaatatg aaaataagta aaaaattact agataatata caaagatttg
    73261 aaaatgttat aaattataaa tttaaaaata aagaatatat actagaagct cttactcata
    73321 gttcatattc taatgaaaat aaaaaatata attttaacga aaggttggaa tttttagggg
    73381 attcggtttt aggcatagtg ataagtgatt atttatttaa tgaagaagct aatctgcccg
    73441 aaggggaact aactaaactt agagcaaata tagtttgtga agattcatta agtgaagtag
    73501 ctaatgatat aaatttaggt attcacatgt tattaggtag aggagaagaa gcaacaggag
    73561 gaagacatag gacttcaata ttagcagacg catttgaagc tgtaatagct gctatatatc
    73621 ttgatggagg ttttgaaagt gcaagacagt ttatacttca tcatatggaa aatataattt
    73681 atgattcaag aaaaggaaat atatttagag actacaaaac gcatcttcaa gaggtgttac
    73741 aagggaatgg agaaaataat atctggtaca ggcttataga agaaaaagga ccagaccata
    73801 ataaaagatt tgtaatggaa gttggaatta atgacgatgt acttggtata ggagaaggca
    73861 agagtaaaaa agaagctgaa cagttagctg ctaaaatagc tttaaagaaa aaattatggg
    73921 aaaaataaat ataatatgta aaaatataaa aagaaatatt tatattagaa ggatgttgta
    73981 gatgaaaaag agaattatac ctatatttgt tcctcacaaa ggatgtcctc atgattgcat
    74041 attttgtaat caaaaaaaaa taacaggtgt gagtactgat gttactagtg aagatgcaag
    74101 aaatataatt gaggaatgtt tagagactat agataaagat gcagatgtag aaatagcatt
    74161 ttttggtggt agctttactg ctatagatat taatatacaa aaaagtttat tatcagttgc
    74221 taaagaatat gtagaaaaag gtcttgtaaa agatattaga atgtctacaa gaccagattg
    74281 tattgatgaa gatatattaa gtatgttaaa agaatataag acaagtataa ttgaactagg
    74341 agtacaatcc ttagatgaaa aagtattatt agatagtata agaggtcatc aatctgaaat
    74401 tgtatacaag agttcaaaga tgataaaaaa tagtggaatc aaacttggat tacagatgat
    74461 gattggtctt ccagctgaca cagaagaaaa gtgtatattt acagcaaaaa aatttgtaga
    74521 gctaaaacca gattgtgtta gggtctatcc aactttggta gtaaaagata caggtcttga
    74581 aaagttaatg gaacaaaata aatataatcc atttactctt gaagagagtg taaatatagt
    74641 aaaaaaagtt cttgtactgt tttatgttaa taatatcaat gtaataagag ttgggcttca
    74701 agctactgat gatatacaaa ttggaaaagc tgttttagca ggaccatatc atcctgcatt
    74761 tagagagttg gtagaagcag atatgataaa agattattta gaatttgtta tttttcaaaa
    74821 taaaaatata aagcaaatgt tggtcaaatc taataaaaag aatatttcta aaatcatagg
    74881 aaataaaaaa acaaatgtta aatatatgga agaaaaattt ggtgtgcttt taaaaacaca
    74941 agaatcagat ttagatataa atcaattaga aattgtgtta gatgggaaaa gtttaattag
    75001 tgctaatatg agagacattc atagaaaatt gtatgacatt tatgaccttt agttttaata
    75061 atgaagggag agaaaagatt tgtatttaaa aagactagag ttaaagggat ttaaatcctt
    75121 tccagtaaaa acagatatta tttttaaaga aggaataaca gccatagtag gaccaaatgg
    75181 gagtggaaaa agtaatatat ctgatgctgt aagatgggta ttaggagaac agagtattaa
    75241 gagtcttaga ggggataaac tcgaagatgt aatatttgca ggtacagata caaaaaaacc
    75301 tatgaattat tgtgaagtgg ctcttactat tgataattct gaaaatcaat tggaattaga
    75361 ttttacagaa gtaactataa gaagaagggc ttatagaaat ggtgaaagtg aattttttct
    75421 aaataataaa agttgtagat taaaagatat aaaagaagtc tttttagata ctggtattgg
    75481 aaaagatggt tattcaatca tagaacaagg aaaagtagat gaaatattaa gtaataatcc
    75541 tttaagcaga agaaaagttt ttgatgaagc ttgtggcata tcaaaatata gatataaaaa
    75601 acaggaagca gaaaggaatt taagtaatac aaaggaaaat ttagaaagaa tagatgatgt
    75661 atatatagaa attgaaaatc aattaaagcc tctttttaat caacagacaa aggcaaaaaa
    75721 gtacttggaa ataagtgaaa aattaaagac acttgaagta aatagcttta taagagaaat
    75781 tgaaggaata gaaaaagaat taagtgaggt taatgaacat cgtaaggtta ttgaaaagga
    75841 gctcaatgaa aaagaagaac aaaaaaatgt tgtagagaaa aagcaagaag atattaataa
    75901 agaggtagag gtattacaag atgtaattga aaaatctgta gattatataa attcaattaa
    75961 aggagttata tcaaaaaaag aatcccaaat aaatttaatt aaggaaagaa taagaaattt
    76021 tacgaatgaa attagtagaa aaaatttaga aataaaggat ataaaagaga agctaaatga
    76081 aaataagcaa tacataaaag aattagaaag caataaatta tcaggtagtg aagaactatc
    76141 taccttgcag gaaaatataa aagtattgga atcaagtaaa gataaacaaa aaattaagtt
    76201 agaatcccta aataatgaga tagaattatt gaaagaaagt ataattgata tattaaataa
    76261 gaaacaagag tttagtaata agctgtccac tttaaacgca aataaagaaa atatgaatat
    76321 cagagatgaa aatataaatt cagagataac agagttaaac aaaaatattg aaataaaatc
    76381 atctgaatta gatactataa ataaagaatt taatatgcaa aatgaaaatt taaagaatgt
    76441 aaataataga cataaagaat tatcaattaa tttgcaggat tcaattagtg aacacaataa
    76501 actagaagat gaaatacaga aaagtaaata taatttaaat ggatataatt caaagttaaa
    76561 tgtctatata gatatggaaa atcattatga aggatttaat agaggagtaa aagaagtact
    76621 aaaaaataaa aatttaaaag gagttcatgg agcattagga cagattataa atgtacctga
    76681 aaagtatgag aaatctatag aagcagctct tggtgcttat atgcaaaata taataactga
    76741 taatgagttt agtgctaagt ctgcaataaa ctatctaaaa cagaataatt taggtagagt
    76801 aacatttctt ccattaaata taattaaatc aaataaaata agtctaggaa atttaaaagc
    76861 aaatactaag ttcataggaa tagcaagtga tttaattaca tttgatgaaa agtatagaaa
    76921 tataattgaa aatatacttg gaagaacaat acttataaat aatatagatg agggcataaa
    76981 atttgcaaaa gaaactggtc ataggtttaa aatagtaact ttagatggtg aaatcttaaa
    77041 tccaggaggt tctttgactg ggggaagtct aaaaactaat gggaatatac tatcgagaaa
    77101 aagatacatt aatgaatata cagaaaagat aagtaatatc aagaatgaaa tttcacatct
    77161 agaattaaaa agagaatctt tagacaaaga tgtgaaaaat atcaaaaatg aaattgattc
    77221 acatgaaagt aaaataaaag atttagaaaa aagtataata ataaaaagta caagtataaa
    77281 gaatgttgag tctgaaattg aatcgttaaa aggtagtatt actaaattag aaaatgagaa
    77341 gaatgattta aattctaacc taaattatac acttgaaaaa agtgatgatg ttagaaaaga
    77401 tatggaagag ttagatgatt tatacaataa aaataaagaa aaaattgatg cattgaatga
    77461 ggaaataaaa agatacaatg atttatatga taaagaaaaa tctgaatttg atgaattgaa
    77521 cttaagttta gtgaagaaaa cagaagttta caatagtata gttagagata taaaaagaat
    77581 atctggtgaa aattgtgagc tagaagaaaa aaataaacaa ttagaagagt cattaaatta
    77641 tgaagaacat gaaataatta aattacaaga ttctatactc actgaagaaa aagaaaaaga
    77701 aaatttaaca aaacaactag gggatagtaa tagaaatctt gaaactagaa aaatagcaaa
    77761 agatgattta aaaaatagtt ttgatgaaat taataaagaa ttaaaaacta tagatagaca
    77821 gcatatagaa cttaaagaaa gtttatttaa agttggtgga agattagaaa gattaaaaac
    77881 tagtcaagac acatatataa ataagttgtt tgagcaatat gatatgacct tagtacaagc
    77941 attggaaatt aaagatgaag atttggatat agatagaaaa ttcttagaaa gtctaaagag
    78001 agaaataaga agtcttggaa atataaatat agactctata aaggaatatg aggaaataaa
    78061 agaaagatac gatttttata gcgaacaaaa gcaagattta gaagagtcta tggaagagat
    78121 agaaaaactt atacatactt tagaagaaaa tatgaaatct gaatttgaaa ttaagtttga
    78181 agaaataagt aaaaatttta aatatgtata taagagatta tttggtggag gttgtggaga
    78241 attaactatt ttagataaag aaaatttatt agaaagtgat atactaataa cagctcaacc
    78301 cccaggtaaa aaaatgaaaa atttaaacct attatctggt ggagagaaag ctttaacggc
    78361 aataagtata ttatttgcta tattgattac aaagccaaca ccattttgta tattagatga
    78421 gattgaagcg ccacttgatg acgcaaatat atttagattt ggagaatttt tgaaggattt
    78481 atctaaagag actcaattta tatcagtaac tcataggaga ggaactatgg aagctgctga
    78541 ttatatctac ggagttacaa tgcaagaaaa agccatttca aaagttatta gtttaaaatt
    78601 aaaagaagct caggaaataa cagatattat ataacttaga ttgacatagg aggaataaca
    78661 gtgttaaaaa aattatttgg ttttggaaaa gacaaggaaa aggaaataga aaaaaaagat
    78721 gctgaagaag aaatagaagt tgaagacagt gttgataatt tagaaaactt ggaagaaact
    78781 attttttcag gacttgaaga agaagtgata gataaagtgg aagatattga agaaaaaaat
    78841 gaggaaagtg tcaataatga aggcactgaa gaaatcgaaa actttgaaaa aatagaagtt
    78901 gagatggata gtaatggaaa agaagtagaa aatatttcaa ataatgattc tcaagaagag
    78961 ataatcgaag aattagaaaa ttatgatgaa attgagtcta aagagataga agataaagaa
    79021 gataagaaag ttaacttgtt tgaaagacta aaacaaggat tgacaaaagc aaagcaagga
    79081 ataactgata gaatagatga agttttaaaa tcatatacaa aaatagatga agaattactt
    79141 gaagatttag aggaaatttt aataacagca gatgttggtg taaatacaac tatggatata
    79201 attgaaagac taagagataa aataaagcaa aaaggtatta ctgaaccaat aaaggtaaga
    79261 gaagaactta aatctatagt tgaagatatt cttacaaatg aaaactctac actagatata
    79321 gaaccagcac catgtataat attaatggtg ggtgtaaatg gggtcggtaa gactactaca
    79381 ataggtaaac tagcaaatag atacaaaaaa gatggtaaaa aagttttatt agcagcagca
    79441 gatacattta gagcagcagc aacagagcaa ttagaaattt gggcaaatag aaccaatgta
    79501 gacataataa aacatcaaga gggagcagac cctggagctg tagtatttga tgctataaaa
    79561 gctgcaaaag ctagaaaaac agatgtatta atatgtgata cagcaggaag attacacaat
    79621 aaggctaatc ttatgaatga acttggaaaa gtatttaaaa tagtagatag agaatttcca
    79681 gaagcaaaac gtgaagtact tcttgtggtg gatgctacaa caggtcaaaa tgcagttgtt
    79741 caagcaaaga catttaaaga agttgcagat ataacaggta tagtacttac aaaacttgat
    79801 ggaactgcaa aaggtggagt agtccttgcg gtaaaatcag aagtagatgt acctgtaaaa
    79861 cttattggag ttggagaaag tgtagaagac ctacaagatt tcaatgcaaa atcattttca
    79921 gatgcattat ttggtaacta atgttctttt aaaaataatg gttgacaaga gtgttgttat
    79981 gatataaaat acaatagtgt aaagtaaata acctttacag tatactgcta ggaagtgtaa
    80041 ggtatgaata tagaaaaaat ggtcgaaatt ggattgttat ttgaacagta taaagaatta
    80101 ttaactgaca agcagaaaga aatagttgct ctatactatg aagaagatta ttctttaggt
    80161 gaaattagtg aaaatctgaa tgtatcaaga caaggtgttt atgatacctt aaagcgttca
    80221 gaaaaaatac taagagatta tgaagaaaag ttacacttag tatcaaagat tcaagagcag
    80281 gaaaaaaata ttaagattat aaaagataaa attattgaca ttaaagaaga tttattgcac
    80341 aatagagatt gtgctaattt aatccctaag ctagaaaata tagaagatgt atgtagggag
    80401 atgataaaat gatatttgaa ggattgtctg ataaactaca aggggcattt agtaagttaa
    80461 aatctaaagg aaaacttaca gaagtagatg taaaaaatgc tatgagagaa gttaaacttg
    80521 ctcttcttga ggcagatgtt aactttaaag tagttaaaga tttcataaaa aaagttcaag
    80581 agagatgtgt tgggcaagaa gttatgcaaa gcttaactcc agctcagcat gtaatcaaaa
    80641 ttgtaaatga agagcttaca agtttaatgg gagatgtaca aagtaaagta atgatttcct
    80701 caaagcctcc tacaatttta atgatggttg gattgcaagg tgcaggtaag actactacag
    80761 caggaaaact tggaggatat tttaaaaagc aaggcaaaaa acctctatta gtagcttgtg
    80821 atatttatag accggcagct ataaagcaac ttcaagttgt tggagaaaaa ttggatatac
    80881 ctgtattcaa tatgggagat aaagaaaatc cagtaaatat tgcgaaagca ggtttaagcc
    80941 atgcgattaa aaatgctaat gatttagtta ttatagatac agctggtaga cttcatatag
    81001 atgaagtact tatggatgag ttaaagtcta ttaaatcaga agttaagcca catgagatac
    81061 ttttggttgt agattctatg acaggtcaag atgctgtaaa tgttgcagaa agcttcaatg
    81121 aggcacttgg tgttgatgga gtagtattaa ctaaattgga tggagatact agaggtggtg
    81181 ctgcactttc aataagagca gttacacaaa agcctataaa atttatgggg atgggagaaa
    81241 agctagatga tatagaacct ttccacccag atagaatggc atcaagaata ttaggtatgg
    81301 gagatgtctt aagtttaata gaaaaagcac aagaaaatat agacttagag aaagctaaag
    81361 aattagagca aaaaattaaa aaacaagagc ttgattttga agatttctta caacaaatgg
    81421 aacaaataca aaatatggga cctcttgaca agatacttgg tatgatacct ggtatgggaa
    81481 atgtaaaaga ccaacttgga gatgtagatt tgaatggcaa agaaatgaag agaacaaaag
    81541 ccataattca gtcaatgact acatatgaga gaagaaaccc aggagtatta aatgcttcaa
    81601 gaaagaaaag aatagctaaa ggcagtggaa ctagtgtaca agatgtaaat agacttataa
    81661 aacaacttaa tgaaatgaaa aaaatgatga agatgtttgc tggttcacaa aagagtatga
    81721 agaaaagggg cggcttaggc ggtttacctt tttttaaata aaatataaaa aagtaaaaat
    81781 tattcggagg tgactgtaat ggcagttaaa ataagattaa aaagaatggg agctaacaaa
    81841 aaacctttct acagaatagt agtagctgat tcaagagctc caagagatgg aaaatttata
    81901 gaagaaatag gatactataa tccaatttct gaacctaaac aagtaagaat aaatgatgaa
    81961 aaagctataa aatggttagc tactggtgct cagccaacag aagtagttaa aaaattactt
    82021 gtaaaaaacg gagtaataga aaaattcgaa gcttctaaac aagcaaaata attttttctt
    82081 ggcaattagt ttaagtaagg gctcattgct aaggttactt taggagatga aatatatgaa
    82141 agagctagtt gtagatatag ctaaggctct agttgataat cctgactcag ttgttgttga
    82201 ggaatttgaa gataatgatg gtatcgtctt aaagcttaca gttgctcaag aggatatggg
    82261 taaggttatt gggaagcagg gaagaatagc taaagctata agaactgtcg taagatctgt
    82321 tgcaaataga gaaaatataa aagtttctct tgagatagta taaaatagga ggattaggta
    82381 taatgcctag tcctttttat ataaatgcgt agtttaagat tttatgatga tatgaccaca
    82441 taagattaaa ttttttaaga aggtgataac atgaaagaaa aattaactca ttttaaggta
    82501 ggtcaaatag taaatacaca aggtttaaaa ggtgaagtaa gagtttatcc gcttactgat
    82561 gatatagaga ggtttgatga attaaaagat ttctatctgg gaaaagattt aaataataaa
    82621 ttggctgttg aaaaagtaag atacaaaggt tctatggtta taatgaagat aaaaggcata
    82681 gacagcatag agaaagcaga aaaactaaaa aataaattta tgtatgtagc tagagaagat
    82741 agcagagagc ttgaagaagg cgaatttttt atagcagata tgattggaat ggaagtttta
    82801 actgtagatg gaaaatatgt agggatacta gaagatgttc ttcaatactc agcaaatgat
    82861 gtctatgtag taaaaggtga ggaagataaa gaatttatga taccagctat aaaaaaattt
    82921 gtacctacaa tagatattga tgaaagaaaa atgattatag accctattaa gggaatgata
    82981 gattaggtgg taatatgaga tttcatataa tgacactttt tccagaaata tttaattcgt
    83041 acatggatga aagtataatg aagagagcag ttgaaaaagg tataattgag gttcatatat
    83101 ataatataag ggatttttct aataataaac ataaaaaagt agatgattat ccatttggag
    83161 gaggagcggg gatggtaatg actcctcaac ctatatatga cacatataag catataataa
    83221 caacccataa tataaataac ccaagtgtaa tttatcttac tccaaaaggt aaggtataca
    83281 atcaatctat ggcaaagcag atgtctttaa aagaagatat aatactacta tgtggtcatt
    83341 atgaaggaat agatgagaga atcattgatt taatagttac tgatgaaatt tcaattggag
    83401 attatgtatt aactggggga gagctcccag cacttataat gatagattct atatcgagat
    83461 taataccagg tgtattaaac caagaagaat catttgaaga agaatcattt aaagacaact
    83521 tattggaata tcctcattac actagaccta gagattttga aggattaaaa gtaccagaag
    83581 tgcttttatc agggaatcat aagaagatag atgagtggag aagagaagaa tctataagga
    83641 taaccaaaga aagacgattt gatttatata aaaagtctaa tgaaaaataa aaatataatg
    83701 aaaaattaat atatatgtat acaataaagt acctataaat ggaattaaaa acataaaagt
    83761 gcttgtaata actattgaag tatagtataa tataaaatgt tgaaaatacg ggcgttcctc
    83821 tgtttacact ggtcgggtag ttaagaacgt ctatgatatc taggaggaag aaagatgaat
    83881 gaaatgctaa gagcaattga gcaagaacaa ttaaaaaatg aagttcctaa ttttggacct
    83941 ggggacacag ttaaagtaca cgttagaatt atagaaggaa aaagagaaag aatacaagtg
    84001 ttcgaaggtg tagtattaaa gagacaaggt ggaggagcaa gagaaacttt cacagttaga
    84061 aaaatgtctt tcaatgttgg tgtagaaaga actttcccag ttcactctcc aaaaatagaa
    84121 aaaatagaag ttactagaaa aggtaaagta agaagagcta aactaaacta cttaagaggt
    84181 agagtaggta aagctgctaa gataaaagaa gctagaaata aataattaaa aactttactt
    84241 ataaatgggg ggctgattta tcagtcctct ttctatttta atgaaaatta cagcaaataa
    84301 ttatactaga aataaataga aatatttgtt gaaaatatac attatttatc tatgaattta
    84361 tagcttttaa aatgaaaaat aaaattggta aatattgcat tatattttgt aacaatatta
    84421 aaaataagag aatagtatta tgtaaagtat gacgttaaaa agatgacaat attatagttt
    84481 gttaagatag attttttaag tggaattagg atataataat ataatattaa taaggagtga
    84541 tacatgtgtc aaatgaatac gaagagtatc ttatgaatga caatctacat ataaactggt
    84601 atccaggtca tatgaaaaaa actaaggagt tagtaaaaaa taacttaaaa ttgattgatg
    84661 tagtaattga acttttggat gctagaatcc cgtttagtag taaaaatcca gacatagaca
    84721 ggcttgtagg agataagcca agagttgtcg tacttaataa gagtgatatg gcagataggg
    84781 ataaattgaa tcaatggatt gaatactata agaaaattaa tatcaaagct ataccagtag
    84841 atacaataaa aggcgttggt ataaataaga taatcgaaga atgtaaaaat gtaactagag
    84901 aaaaaatgag ttctttaaaa gacaaaggga gaaaagaaag agctatacga ataatgatag
    84961 ttggagttcc aaacgttggt aaatcgtctc ttataaacaa attaacaggt agaaaaagca
    85021 ctcaaactgg agataagcca ggagtaacga aagggaaaca atgggttaga ttaaagggaa
    85081 atcttgaact tttagataca cctggaatac tttggcctaa gtttgaagac caagaagttg
    85141 cattaaattt agcatttagt agagctataa aggatgagat tttagatact gaaactttgg
    85201 ctttaagact tatagaaaaa cttatgaaaa tagaacctga gaagttgaaa gccagatata
    85261 agttagattg tctaggagaa actccaattg aaactatgga tatgattggc cataaaagag
    85321 ggtttataac aggtaaaaaa gaactagatt atacacgcat agccacaact gtattaaatg
    85381 aatttagaga tggaaaaata ggaaatataa cattggaagt tccagaaaac gttaaaagat
    85441 agattttaaa acaaaatcaa aaatttaatg ttaaaaattt aaaaaagcct tttagcaaag
    85501 gcttttttat ttttttgaaa tatagacaaa tatctccata taaaagtata aattaggtta
    85561 gaaaaccttt aaaaatatta atttaagaca aatataccta atgttttgaa aattaaaatg
    85621 agtgtgatta tttaaaattt tagcatattg acttgcttgt tt
//
LOCUS       DAEORM030000011        82572 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.011, whole genome shotgun sequence.
ACCESSION   DAEORM030000011 DAEORM030000000
VERSION     DAEORM030000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 82572)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 82572)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 82572)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..82572
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.011"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     misc_binding    96..336
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     misc_binding    402..637
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            722..1939
                     /locus_tag="KRH23_001099"
     CDS             722..1939
                     /locus_tag="KRH23_001099"
                     /EC_number="1.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004412 - homoserine dehydrogenase
                     activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HHS5224388.1"
                     /translation="MENKVKIGVLGYGVVGSGLIDIIDNNKEKRNIEIVGILVNNLEK
                     HKDKKYSNIITNNIDDIFNKDIDILVEVMGGLEPSLSYIKKALNNKIHVVTANKDLLA
                     ECGDELAKLASENKVSIKFEASVAGGIPVLKPIIESLEGNNIDSINAILNGTTNFILS
                     KMYDENLSYDMALRQAQELGFAEANPESDVLGYDAARKLSILSTLAYDNRVYWKDVYL
                     EGITDIDEKDIEYAKKLNCKIKLIGQSKYENDKVSAFVRPVLVEKDNILARIDNEFNA
                     VIVNGDSVGEVSFVGKGAGSLATGSAVYSDVIDIIDNRVSSIDSFTKDKIQVNKIVRE
                     KCGALLRFKKCNKDEILNIVENCLVKFDILNDDDELAIMVYADSEYEINNSLCLIKDK
                     GYCEKMNKMLKIS"
     gene            2056..2538
                     /gene="cdeM"
                     /locus_tag="KRH23_001100"
     CDS             2056..2538
                     /gene="cdeM"
                     /locus_tag="KRH23_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exosporium morphogenetic protein CdeM"
                     /protein_id="HHS5224389.1"
                     /translation="MENKKCYSEDWYERGESTAKWFQNDREEYEREAYDEDRERRGSN
                     CGCSDSGENRPRNCERFRREAEIREREAREAFCESSEKKKEALAYECEARKLWEEAEK
                     YWDEYSKYNYKGIEYLAEAARLFDEGMECEARRNGNNGGNNNNCCHKCHKCNCNCCRK
                     "
     gene            2803..4068
                     /gene="hisD"
                     /locus_tag="KRH23_001101"
     CDS             2803..4068
                     /gene="hisD"
                     /locus_tag="KRH23_001101"
                     /EC_number="1.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004399 - histidinol dehydrogenase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol dehydrogenase"
                     /protein_id="HHS5224390.1"
                     /translation="MKSIKTSSMKEKVDEKILREQVSSIIEDIRNNKDVALKKYNEKF
                     DRNTRDEFRITKEEIKEAYKHVDDEFINNLKIAAKNIREFAKAQKLSFENPFEKEIYP
                     GVILGQTNIPIESCLAYVPGGQYPLFSTALMLIIPAKVAGVKRIVACSPTMKNTEKIN
                     PKTLVAMDIAGADEIYATGGVQAIAAFTYGTEKINPVDIIVGPGNKFVTEAKRQCYGQ
                     VGIDFVAGPSEVLIIADETSNPVYIAADLLAQCEHDLNARGILLTNSLEVAQKVEKNI
                     ESMLKDLPTKDIAYSSWENNGEIILVDDMEEAIKISNFYAPEHLEVAVNEYNDICDRL
                     TNYGSLFIGNLSAEVFGDYVSGTNHTLPTLKASRYTGGVWVGTFIKTCTKQIFNEKAI
                     QSLAPVAEKLAKEEGLYAHAKAAEVRFKK"
     gene            complement(4271..5023)
                     /locus_tag="KRH23_001102"
     CDS             complement(4271..5023)
                     /locus_tag="KRH23_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HHS5224391.1"
                     /translation="MSYFQYQGNSCFYKEYGQGKPIIFLHGNTGSSNMFKALVPLYAE
                     NFRCILIDFLGNGQSDRVSQFSPDIWHDEALQTIALIEHLNCGKVGLIGTSGGAWAAV
                     NTGLERPDLVEAIIADSFDGRTLNDNFIDNLITGREKSKQDIQARKFYEWCQGKDWEN
                     VVNLDTKALLQCANEKRPLFHKELCKLEMPILFTGSKEDEMCRHNLEEEYKQMATFIS
                     KASIHIFSQGGHPAILTNADEFAQLAKVFFNY"
     gene            complement(5141..5410)
                     /locus_tag="KRH23_001103"
     CDS             complement(5141..5410)
                     /locus_tag="KRH23_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CD3324 family protein"
                     /protein_id="HHS5224392.1"
                     /translation="MSYQNSIDLLPKELIEQVQEYIDGKVIYIPKKQEHKKHWGENTN
                     TKQVLASRNSQICINFQNGMSIKQLSEKYFLTEKSIQRILKQQNL"
     gene            5885..6979
                     /locus_tag="KRH23_001104"
     CDS             5885..6979
                     /locus_tag="KRH23_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HHS5224393.1"
                     /translation="MKNIVGKPQTIKKVNEDLIKNIIKNEGPITKPEISSITELSLAT
                     VNKIVEQLALKNEVKVSGLSESTGGRRAQLFEINANLEHIIALYYYRNCCIGVVANLL
                     GEIIYQEEFNIRMDTYENVNQDTFFVIDTLIKKEKGNNIRAIGIGVPGVVKKGVVKNI
                     PTIKSWEGINLENLIKSKYNTKVFIENDTNITTIGIYQKQYKDKYKNMALMYLEDGIG
                     SGIVINGELYLGSTNFAGELSYLNIEFGKYNSNNLNLEDYIMSLRKRYLESKDNKFKK
                     EILSIISNFIRTLVCVLNPQAMIIQCSILTKSDMEFIEKDVSNNVGEENFPKLIKVDS
                     LREGSINGVISMCLKETDYQYSLSNKKGGY"
     gene            6981..7931
                     /locus_tag="KRH23_001105"
     CDS             6981..7931
                     /locus_tag="KRH23_001105"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0045127 - N-acetylglucosamine kinase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine kinase"
                     /protein_id="HHS5224394.1"
                     /translation="MKYLVSIDGGGTKTKFCVSDLDGNILKEHTTGSTNYKSVGIKKT
                     YENINNGFKKILKDLYIDYDDIEYTVFGISGCDSPNDYKIIMDEILKIGINKEKIYLA
                     NDAVLAFYAQADSPGLVIVAGTGSIILGIKEDGEIYRVGGWGYNFSDLGSGYDIGRKL
                     LKKVLLYCDECHEYSDLFSCVLDFFGANSFEQLAYMITDINNNVEIANLASLVIDCAE
                     QGDKLAIEILRESSTELSKLAQVILRKISNPMKMDKSEINIVLSGGTLNKTVYAQMLM
                     NNLKTENTDKNLKFISQENQPVYGGIRLAMALANRRVKHG"
     gene            7924..9108
                     /locus_tag="KRH23_001106"
     CDS             7924..9108
                     /locus_tag="KRH23_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224395.1"
                     /translation="MDRKKVIVQIFTGGFKAKEIKFNDIKCKLLELLDCIDIEKVIMG
                     WSVDEELYVETKKLLNKYNVELYLWLPCFSEIGLLEKSNLLIDYMGKEVKGYALQEDE
                     NFEFYCPNNKENIKNIKKIYSTYFSDIKFDGIFLDKIRYGSFSNKLNGVFNCFCKDCL
                     NIYEKNNIDKESLMREMNNVSKGVIDNEDAPFGITEYINGKYKFKNKIWEDFFETKNQ
                     NIYKALLEISSYFKSKGLKIGIDTFSPFISYFTGQDLEKLQEVADFIKPMMYRTTKAP
                     AGLPFEFERFIDESIHKNKEIGKRNFLDILGIKEYEGDVYPIEFVLEEIDFMTRNLNK
                     DIYVGVEINKKEIISPVTPKYISENISNINKTTVKGYVLSWDLLSAPKENIDEIIKWF
                     RN"
     gene            9121..10617
                     /locus_tag="KRH23_001107"
     CDS             9121..10617
                     /locus_tag="KRH23_001107"
                     /EC_number="7.5.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HHS5224396.1"
                     /translation="MSKILEMQQIYKSFGKVDVLKGINFELEKGEVRALLGANGAGKS
                     TLIKILGGVHSQTKGKVILTGNEIMFKNPHHSKENGISIIYQELSLIPTLTVLENIFL
                     GREILKGSVFLNKKDMLEEYMKICEDFDFNIDPHIVVSNLSVANQQMVEIMKAVSCNS
                     EIIIMDEPTTSLTNNEKDGLFKIISRLKSKGKTIVYISHILEEVFKVCDSASIMKNGI
                     MIGTYDVEDLTKLKITQLMTGNDNHKLIEKKDYTFAKYEEPPVLEVKNISWSNKIKNV
                     SFKVYRGEVVGLAGLVGSRRTEIINLIFGIDNKDSGDIFINGKKVDIISPKVAIKNKI
                     GLIPEDRKNLGLILEQAIYTNSSSVQIDKFKKFLFIDRNKEIEFSKKGVKELGIKVSD
                     VKQEVKELSGGNQQKVVVSKWLEKDLDLIIYDEPTKGIDIAAKEEIFNTIKEFSSKGI
                     GVIFISSDLEEVIRVSDRILVTREGSIVDDLKNENIQVQDIMNSIFNV"
     gene            10640..11590
                     /locus_tag="KRH23_001108"
     CDS             10640..11590
                     /locus_tag="KRH23_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHS5224397.1"
                     /translation="MKKAFEKLNLRDYGVLLGFLALCIAISIATPSFLGKQNILNLLR
                     QSSIIGIISAGMTFVIISGNFDISVGAVAALAGAITMKFATGGTNLFASMLLGVAICA
                     VIGLINGIVVAKINVPSLIATMAMVTIVRGLLLMLTRGYPITENIPILDYIGNGYLFS
                     IPIPVVIFFIVVLASFIVLNKTKFGRYVYSVGGNQEASKLNGINVDSHKVKVFIINAV
                     LAGIAGIVLTGRLGTATAIAGEGYDMDAIASVVIGGTSVAGGSGSVLKTVIGVLLMSV
                     INNSFNLLGIDVYFQYIFKGLIILAAVGFDSYSKKKLASR"
     gene            11611..12573
                     /locus_tag="KRH23_001109"
     CDS             11611..12573
                     /locus_tag="KRH23_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HHS5224398.1"
                     /translation="MKKLMKHLALLLSLVMIFGLVGCSNGGDKEKNGEKKIAVLLPGS
                     TGYFVATKQGIDAKSKELGVSVEYADAQWDASKQLSQAEDFMAKGVDMIALCGVDSAV
                     SERIVKAANDSDVPIVAFTNSIGSNPTGEFKGLVTYIGQNEEETGALTGKIAKNLLGE
                     TGGKAVLIEGVPGTTPQVLRKKGLEKELKDSNIEIVYNQTSNWEKEQALKVTEDLIQK
                     KTDFNVIICQDDNSATGAGQALKDAGLKDKVKVIGLGGSKDGLKAITDGLIDGTTYMS
                     AVEEGGLVIEKASKFLKGEKIEPVTQIKQVEVNKDNISEFKGEW"
     gene            12945..13577
                     /locus_tag="KRH23_001110"
     CDS             12945..13577
                     /locus_tag="KRH23_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HHS5224399.1"
                     /translation="MARRLFLERIGLIFLGSAILAFGVYNFYYLNNITEGGVLGILLL
                     LKNLFNIQPAIANVVIDGLLLLVGYKFFGKKFLIYSIVASITFSVLYDLFEAIGPLVP
                     QSQNMLLSTILAGVTVGTGVGIVVKAGCASGGDDALALVISKTTSLNIGQVYLATDVI
                     VLLLSLFYLSAFDIFYSLIAVTISGKVIDFIYYHGKSLDMDISNDIVPEC"
     gene            14003..14080
                     /gene="kdpF"
                     /locus_tag="KRH23_001111"
     CDS             14003..14080
                     /gene="kdpF"
                     /locus_tag="KRH23_001111"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: protein motif:HMM:TIGR02115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0031004 - potassium ion-transporting
                     ATPase complex [Evidence IEA];
                     GO_process: GO:0006813 - potassium ion transport [Evidence
                     IEA];
                     GO_process: GO:0043462 - regulation of ATP-dependent
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="K(+)-transporting ATPase subunit F"
                     /protein_id="HHS5224400.1"
                     /translation="MWFLAVVIIMLIIYLVYALINPEKF"
     gene            14127..15803
                     /gene="kdpA"
                     /locus_tag="KRH23_001112"
     CDS             14127..15803
                     /gene="kdpA"
                     /locus_tag="KRH23_001112"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0031004 - potassium ion-transporting
                     ATPase complex [Evidence IEA];
                     GO_function: GO:0008556 - P-type potassium transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006813 - potassium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="potassium-transporting ATPase subunit KdpA"
                     /protein_id="HHS5224401.1"
                     /translation="MVQIVIVLAIFMILVIPMGKYLYHIATNQKTFGDRLFDKVDNFI
                     YKVCSIDKKKEMNWKQYALALLFTNAVMVFIGYIILRTQSMHIFNPSGIKSMEQGLSF
                     NTIISFMTNTNLQHYSGESGLSYFSQMTVIIYMMFTSAATGYAAAMAFVRGLVGKKKT
                     LGNFYVDLIRITTRVLLPGALIIGLILVTQGVPQTFAGTETVTTIEGKLQDIARGPVA
                     ALESIKHLGTNGGGFFGSNSSHPFENPTIISNIVEILSMMILPGACVVAFGHMIKNKK
                     QGWVVFGAMSIIFLIGLVVCFKAESAGNPILSQLGLNQSMGSMEGKEVRFGIAQSSLF
                     TTVTTSFTTGTVNNMHDTLTPLGGLVPLLNMMLNVVFGGKGVGLMNMLMYAIIAVFLC
                     GLMVGRTPEFLTKKIEGKEMKLIALLIILHPLLILMFSGLSVAIPAGLEGISNPGFHG
                     LSQVLYEFASSAANNGSGFEGLGDNTMFWNITTGIVMFFGRYVSIIVLLAISSLLASK
                     KAVNESIGTLRTDNFTFTIVLVLVVLIVGALTFFPALALGPISEHLVLWH"
     gene            15828..17885
                     /gene="kdpB"
                     /locus_tag="KRH23_001113"
     CDS             15828..17885
                     /gene="kdpB"
                     /locus_tag="KRH23_001113"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0031004 - potassium ion-transporting
                     ATPase complex [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008556 - P-type potassium transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006813 - potassium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="potassium-transporting ATPase subunit KdpB"
                     /protein_id="HHS5224402.1"
                     /translation="METKKTKFITKDIFKTSIIEAFKKLNPKYMMKNPVMFVVEIGFI
                     VTLILTIVPSLFGDEGNNLRAYNGIVTIILFITVLFANFAEAVAEGRGKAQADTLKKT
                     RKDTVARVIDTLGNEKMISASELKLGDIVLVNAGEVIPNDGEVIEGIASVDESAITGE
                     SAPVMRESGGDFASVTGGTTVVSDWLKIRITTKPGESFLDKMIALVEGASRQKTPNEI
                     ALNTLLVGLTLIFMVVLISLYPMANYAGVKIPISTMIALLVCLIPTTIGGLLSAIGIA
                     GMDRVTRFNVIAMSGKAVEACGDVDTMILDKTGTITYGNRLASEFIAVGNADSKDLIN
                     YSVMCSLKDDTPEGKSIVDLGMKLGSTGKTKEAEEAEFVEFSAQTRMSGINLADGRAI
                     RKGAYDSIIKRVKESGGTVPEDLEENVNRVAKLGGTPLVVCVDNEIYGIIYLKDTVKS
                     GLVERFARLREIGIKTIMCTGDNPLTAATIAREAGVDGFIAECKPEDKIDAIKKEQLE
                     GKIVAMTGDGTNDAPALAQADVGLAMNSGTTSAKEAANMVDLDSDPTKILEVVEIGKQ
                     LLITRGALTTFSIANDVAKYFAIIPAIFTLAIPQMEILNVMKLSTSFSAILSALIFNA
                     IIIPCLIPLAMKGVKYRPMKSQAMLMRNMLIFGLGGVIVPFLGIKLIDLLITPLVMVL
                     NLG"
     gene            17904..18530
                     /locus_tag="KRH23_001114"
     CDS             17904..18530
                     /locus_tag="KRH23_001114"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="K(+)-transporting ATPase subunit C"
                     /protein_id="HHS5224403.1"
                     /translation="MKTLKPALLVSIVLLVVCGLVYPLVLTGVSQVAFKDKANGSMIE
                     VNGVKVGSELIGQSFTDARFFKGRVSSVNYNTYTKEDLVPDKDGNTSYGGVSSGSFNY
                     GATNPELHDRVQKDIEQFLKDNPTVKREDIPTDLLTASGSGLDPNISPASAKIQIPAI
                     AKASGISESKLQKIVDDNTSKKLFGVLGEDRVNVLKVNVEVAKILGLI"
     gene            18767..19675
                     /gene="cysK"
                     /locus_tag="KRH23_001115"
     CDS             18767..19675
                     /gene="cysK"
                     /locus_tag="KRH23_001115"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004124 - cysteine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HHS5224404.1"
                     /translation="MLYNNALELIGNTPVVRLNNLGCTNGCSNIYVKLEKVNPAGSIK
                     DRAVYEMLEGLEQRGELKKGDVLVEATSGNTGIALSMIGKLKGYEVVIVMPETMSVER
                     RNLMKAYGANLVLTDGKAGMAGSIEKANELLKENPNYKSLKQFENKDNPNAHYKTTAV
                     EIMNDVKDLDIFVCGVGTGGTLIGTARYLKEQNPNIRVIALEPKKSPAISENKTGPHK
                     IQGIGANFVPENYDSSVVDEVILVDDEDAFDTVKLLAAKEGILVGISSGANIFGAIEM
                     AKKYPDKKIVTVAPDGVDKYMSMGIF"
     gene            19702..20292
                     /gene="epsC"
                     /locus_tag="KRH23_001116"
     CDS             19702..20292
                     /gene="epsC"
                     /locus_tag="KRH23_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009001 - serine O-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase EpsC"
                     /protein_id="HHS5224405.1"
                     /translation="MFKKINKDIEYIMKNDPAARSKIEVFLLYPSVHAMIMHRMAHAL
                     YKKKKLFTARLISQISRFMTGIEIHPGAKMGEGILIDHGMGVVIGETAEVGNRVTIYQ
                     GATLGATGKDTGKRHPTVGDDVLIGAGTKILGPLNIGSNSKIGANSVVVKDVPNGATV
                     VGIPAKIVKIRNLEPVKKNKKEVSYEYDELDNVYYI"
     gene            20452..20640
                     /locus_tag="KRH23_001117"
     CDS             20452..20640
                     /locus_tag="KRH23_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HHS5224406.1"
                     /translation="MKANVNQDTCIGCGLCPSICPEVFDMKDDGKSHVIVDEVPSDAE
                     ESAAEARESCPVDAIDVH"
     gene            complement(20694..21563)
                     /locus_tag="KRH23_001118"
     CDS             complement(20694..21563)
                     /locus_tag="KRH23_001118"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HHS5224407.1"
                     /translation="MKLNRNDSCWCGSTKKYKKCHMDMDNKIDSFAKLGHIVPTHDII
                     KNESQIEEIKKSAVINTKILDYISDKIEIGMSTEDINKLVHDFTLQNGAIPAPLDYNG
                     FPKSVCTSVNNEVCHGIPSKDIILKDGDIINVDVSTIFNGYYSDASRMFMIGNVNENA
                     KKLVQVTKECVQKGLEVAKPWGFLGDIGDAINSYAKKNGYSVVREIGGHGVGLSFHED
                     PFVSYVSKKGTEMLLVPGMIFTIEPMVNEGTHEIFVDEENNWTIYTKDGKLSAQWECM
                     VLVTETGVEILTE"
     gene            complement(21760..23004)
                     /locus_tag="KRH23_001119"
     CDS             complement(21760..23004)
                     /locus_tag="KRH23_001119"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthrax toxin lethal factor-related
                     metalloendopeptidase"
                     /protein_id="HHS5224408.1"
                     /translation="MENNLNTAKRNNTELLQNDSLKVNLQIGVDFTLLSKSLKAFYKK
                     EKDFYCIALAPCNVSSEKANRKISIYDMIKEINILIESITDKNELLSEELFTNNLSEF
                     YDESLDEIYIDLKQAYLYIKKNTDSLNIEDSIEYVFDVDISNDIKAKENPLINFNSLS
                     LVVWSGETKHILQQMNILDLEDIHSYSIENNTNITIYENNTLQYKFNEESENIKDSSI
                     DIIEQMLILPDDLNYDKDEVENMKNRLAKINIKYLQTLKEKDIKIKLINSNLTDEPEF
                     SDLKYQLPPCWVRSGKTWKDVPGIYRNNSIVAKIGYSNPSYANVHSSKNLELHETAHA
                     IDKNVLNKKSNSEEFMEVFAQERYKLYDPKQVAHAYISKFIEEFFAESFVHYYLDEDS
                     KNTLKENCPLTYDFLEKLELNY"
     gene            23277..23588
                     /locus_tag="KRH23_001120"
     CDS             23277..23588
                     /locus_tag="KRH23_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HHS5224409.1"
                     /translation="MYFTYIIRCKDDSLYTGYTSNIVRRMNEHKLGINSKYTRAKGFE
                     KLEVYFVTNTKSNAMKLEYYIKKLTRNKKLSIIKNPSILINLIDNKEDYIIGKEIEQL
                     T"
     regulatory      23681..23773
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            23873..24667
                     /gene="thiD"
                     /locus_tag="KRH23_001121"
     CDS             23873..24667
                     /gene="thiD"
                     /locus_tag="KRH23_001121"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008902 - hydroxymethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0008972 - phosphomethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HHS5224410.1"
                     /translation="MSNYKIPTLTIAGSDSSGGAGIQADLKTFSAIGTYGMSVITAIT
                     AQNTKGVFAVEDLNKKIIKKQIEAVFEDIPPRAVKIGMVSSPEIILEIVENLKKYNPK
                     YLVVDPVMISKSGYYLLKPEAKENLIKYLIPLAYIITPNIPEAEEITGIKIHNVDDMK
                     RVGEEILQLGPKFVLMKGGHLDGEAVDILVGKNIFKVYKSERIDKKNTHGTGCTLSSA
                     ITSYLALGYEITEAVNLSKIYITEAIKRSFDIGHGVGPVHHFYKFE"
     gene            24691..25479
                     /gene="thiM"
                     /locus_tag="KRH23_001122"
     CDS             24691..25479
                     /gene="thiM"
                     /locus_tag="KRH23_001122"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004417 - hydroxyethylthiazole kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HHS5224411.1"
                     /translation="MYNLIKDVKKLNPLVIHYTNNVTINDCANVTLAVGASPLMSFSY
                     EEVEEMVSVANSVVINIGTMNSNMLDLFLLAGKAANKYNKPVVLDPVGVFASKARAEL
                     TSRLLNEVKFSVVKGNVSEIKFIGGFNVRGKGVDSFDEEEDSTEIIRKIAEKLECVVV
                     ATGKIDIITNGKGTYKINNGTDKLKGITGTGCMTASLIASFMAVTENILEAATMGVLT
                     MSLSGELANLNNPPIGTFKENLMNAIYQMDIDTLSKNSNIEFLN"
     gene            25502..26134
                     /gene="thiE"
                     /locus_tag="KRH23_001123"
     CDS             25502..26134
                     /gene="thiE"
                     /locus_tag="KRH23_001123"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004789 - thiamine-phosphate
                     diphosphorylase activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HHS5224412.1"
                     /translation="MIDKESLKKCLKLYLVTDSEMLKGRDFYKCLEDAISSGITTVQL
                     REKNASGREFLRKAMKLREITKRYGVKFIINDRVDIALICDADGVHVGQSDIDVREVR
                     KLIGNNKILGVSARTLEEAICAKNDGADYLGVGSIFTTSTKLDAKSASFETVKEIKEK
                     VDMPFVLIGGINLDNIDKLKCLESDGYAIISAILKAEDISKEVEKWTLKI"
     gene            26273..26575
                     /locus_tag="KRH23_001124"
     CDS             26273..26575
                     /locus_tag="KRH23_001124"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HHS5224413.1"
                     /translation="MIRILLVCVGGMSSTLLVNKMEKDAKKRNIDCKIWAVGEGDIKS
                     ELDNFDILLLGPQLRFMLDDVKSIVGDRAPVSIIDMVNYGTCNGHAVLNSVLEILK"
     gene            complement(26641..27390)
                     /locus_tag="KRH23_001125"
     CDS             complement(26641..27390)
                     /locus_tag="KRH23_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHS5224414.1"
                     /translation="MLNILWRSMKWRFKNPISFVVTILQPFLWLVLYSSIANQTMNNI
                     NINNYTAFILPGIIVLVVFSSCSSGGIINFIMKNSGSFYRVLIAPISRYSIVLGQLLE
                     AILVSFIEVTILCIVSIFFSVRIESGIGGILLMIVLIFMTAFFLSSLAYSISLLLPNE
                     IVYETIMTAIVLPIFFLSSALFPIESLSGGLKVAVMLNPFTHVINALRSLIFGETILI
                     GDILPVILLFLILCCSSFSLAMWRLKKEMVS"
     gene            complement(27384..28346)
                     /locus_tag="KRH23_001126"
     CDS             complement(27384..28346)
                     /locus_tag="KRH23_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HHS5224415.1"
                     /translation="MLAIEIDNLVKEYKNGVKALNGLSFNVNAGEIFSLLGPNGAGKS
                     SLINILTTFYKPTSGNVTMFGKDLVDNPSWIRTQIACVAQQISIDEHLSLMENMVFQS
                     KMYKVEPQIAKQRIDSLIDKFDLSSYLKYPTSSYSGGVKRRLDIAMNMVSSPKILFLD
                     EPTVGMDVDSRKSMWDMLLKIRDEYGTTIFLTTHYLEEAEQLSDNICIMKNGKDLAQG
                     TPSSLRSYIRQNILRITFHNTEDIKKYKDSIKSTGLVKFMSVRENSIFISVNDSRTAF
                     TLINKWLLEHDIEFDAIEIVEPSLEDVFLALTSSKKSLKEEWEC"
     gene            complement(28350..28808)
                     /locus_tag="KRH23_001127"
     CDS             complement(28350..28808)
                     /locus_tag="KRH23_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HHS5224416.1"
                     /translation="MNCKIEIKNIESVTVATMRYNGPMTEATKYFPNVFKAIKGKSNG
                     APFFCYYDVDQKTGVAEMELCVPTAETPNRMGITTKEFPKTKALFFTHTGSYSNLPKT
                     YEMIFKYIHENNIKIQTPWREVFIKGPGMLIKGNPDNYITEIIFPLKEEE"
     gene            29164..29520
                     /locus_tag="KRH23_001128"
     CDS             29164..29520
                     /locus_tag="KRH23_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HHS5224417.1"
                     /translation="MNFELDNTTPIYLQIVKYIKRQIVTGELKPGETIPSRREMALNL
                     KVNLNTVQRAYKEMGDMNIINTFKNYQSSVTVDENILKNLKLELINESLSVFIEDMKA
                     INVSKEEVLKIIEDKY"
     gene            29592..30308
                     /locus_tag="KRH23_001129"
     CDS             29592..30308
                     /locus_tag="KRH23_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHS5224418.1"
                     /translation="MIEIKNVSKTYKRMQGLKIRKIEALKNVSFNIEKGKITALLGIN
                     GVGKSTMLKAIAGLINIDSGEIRIDGEKINEKVYNKLAFVPDVQSHFSNTTIKETFEF
                     MEIFYSKWNKEKSKEMMDIFKLDEDEIIDNLSKGNIARVKLILGFCQDPEYILLDEPF
                     TGIDLFKREEFIGVIAQYMEENQAIIITTHEIVEIESLVDEVVILDEGQIITSFNAEE
                     LREREGKSILDKMREVYKNE"
     gene            30301..31125
                     /locus_tag="KRH23_001130"
     CDS             30301..31125
                     /locus_tag="KRH23_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHS5224419.1"
                     /translation="MNKLLYLINVDLRRSNKFYIAYISFFSLITLSLNLFEINKFKNS
                     KFIMNLAIEDFGGIFYGLGILSNLGFIQSILFFGILGLFIYYIFMWKREFFSNNQSIY
                     TLMMLPQNKFKICISKSIALITMIYGFLISQTATLFICKYIFNFIFRNMPIINMNFAK
                     DLYYLNLKSIPIDFISFMAIYVFLLLIAISIVNCCILFIFSYINKFYVILITLLIIAG
                     LYFSTIYINIITLFRKYYNLIGFQFNNLVAGLLSFLIIMFILNGISYLLIKKKVSL"
     gene            31137..32336
                     /locus_tag="KRH23_001131"
     CDS             31137..32336
                     /locus_tag="KRH23_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224420.1"
                     /translation="MKLKSKISILIIFLTLAIYFSIGLLNNEDNLKIKTIKGDSNELD
                     HININFGYVLNGYINSYYTINGSNKTKKTELIKLQKDSKNTNNLIDVSSGSDLIAHVG
                     FEMNEESKDINFVIDEKKEDLEKGVFPSEGSDKEIEYEKLDMNNFTRTRYKVDKSTDD
                     YYANILASKRYKKYLYVSVLYATSDSSENNKEYSSTIDIIKINPENKKIKTIKSINLS
                     NYFSEKYQNIETIGVSYASKYEDKMYILVNVLNTNIGDNSNSKFHLLEYNLEENKESI
                     MELKTDSKMALAKAKLEANKLYMVMSNDYDNSSITELNLLTYNILDKSLDEDKYVLDN
                     REKRGIRSIEIDSNKIVAYTSRLNSILSWDNKFMLYIINKNSKEIVYEGELQFNSSNS
                     MLEFEIK"
     gene            32345..33157
                     /locus_tag="KRH23_001132"
     CDS             32345..33157
                     /locus_tag="KRH23_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224421.1"
                     /translation="MKDLIRLFEFELKRNIKNYIFIIICCCSFVILNIVKNLNDYNYI
                     IENAVKSEQLTKIGNTIETVKVTGFSSFRNIMGSTESWFMFGIIACICYSFFIWYRDF
                     NGRSKSIYTLIMLPKNRINIYISKLLNILFLVYSYTVVLTISLFIASKLLPRHMLGNV
                     TNYGFVQETIYELKMLLPYSFEILFVEYIFLLIGFVSVVFTSILINKSIYKVSTLISF
                     LFLVIEILVFIISIEFIIPYEYSDVFTVLYSSINIFVCSLISNKLLKQKIDF"
     gene            33168..34436
                     /locus_tag="KRH23_001133"
     CDS             33168..34436
                     /locus_tag="KRH23_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224422.1"
                     /translation="MKAKNIGKYTICFIIVCFLMITMTLILSYFNKDKLSVKTLKGNV
                     KDIGRVSVVYTPNISKFSYEEVIISKNGVRNNTNPKSRIRNDYLNIDKKYSDFVNDKG
                     KEFIYKDDLNIGEAYTSVKSDLVQGMNALNDCIKVSNKNLKSGVEENFDINLNKSDFK
                     ENSWKTLFNKIYKGNLYMVISETNISGSKVNNICILKIDIKNKSYKLLNRFNLGLQNG
                     EQQNINEIKFSIGSKLYLEIVNNKSKNGYIEGHDSYSNFIIYDIEDNTFNISNKFMDN
                     LNKEKNANPKEIGLLSKTKLDYMVKNNKLNLIVTDMSNSITNLVYDINSNEIKLEDYE
                     ILDLKVDYNEASSGVRKVKLLDDKIYSISGIKNSISGELKGFKGIVDVVGTKPVKFQV
                     FDMKLKKNIYEAELINGDISLQEKLFFVAN"
     gene            34830..36011
                     /locus_tag="KRH23_001134"
     CDS             34830..36011
                     /locus_tag="KRH23_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HHS5224423.1"
                     /translation="MNKKYIKAGNLIDGTGNSIMQNKGIIIDGDTIVEIEDIRDDLNG
                     YDVYYYLDKTVMPGIMNCHVHLTMEPVGNPKIYYDNVSDVELVVNTIKQLDAYLDSGV
                     TYIRSLGCPKYVDVQLKNLIDKGSIDGPGIVTSGPVICMTGGHGYYFGIESDGVDECR
                     KSARTVLKNGVDCVKIMATGGVTTDGVEPGSPQLTLEEMKAAVDEAIKAGKITATHAQ
                     GRTGIKNAVLAGITSIEHGVYLDDEIIDLMLERGTYLVPTVAAPYFILNAGKESGITE
                     ATLRKCEIVAIPHKESFLKAYKKGIKIAVGSDAGTSYNEHGKTYYEMKLMSDYGMDNM
                     DIIVAATKTASELLRIDKNYGTLEKGKKADVIVVNGNPVENIDVLADVLAVFKLGKKV
                     R"
     gene            complement(36153..37070)
                     /locus_tag="KRH23_001135"
     CDS             complement(36153..37070)
                     /locus_tag="KRH23_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CotA family spore coat protein"
                     /protein_id="HHS5224424.1"
                     /translation="MENNKCREDFRFTQEYEEDYPNTNERYYENYQVADRYYNYPNKY
                     KEPKIKQCCCKKSMREALELLRYDALRPFVNFNQFAFISDFFIVGANLVGIDLSAPPK
                     DNLSGLDGTFERFSACNCDLIDIAGRVSYPIPVPLTLEGLINTIGTIPGVAELIALID
                     AVIPPTIDLGAILDAILAAIIDFILAASTPLANVDLASLCNLKAVAFDITPADYEDFI
                     ASLGYYLDKKHYKECNCNCDCDDCCCNKGILDNLYMSNINNQVTVVAGSLVLTGVEVL
                     GKKNDVIVLGNSNDSRIYFVCVDSIDYIA"
     gene            37323..38117
                     /locus_tag="KRH23_001136"
     CDS             37323..38117
                     /locus_tag="KRH23_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHS5224425.1"
                     /translation="MIEVDKLCKSFTRVVKDDKNKSSIRKLKKVKTKKEEFFAVNNVS
                     FKVMEGEIVGILGPNGAGKTTLLRMLGGILTPTSGSINISGYDYSIDRNSAKKEIGYL
                     SGNTKLYGRLSPRELLTTFASLYEMSKEDIEESIENIVKIMDMSEFIDNRIENLSTGQ
                     TQRTSIARCLIHSPKVYIFDEPTLGLDVLSSASIIDFMKNEKLRGKTVLYSTHYMEEA
                     ETLCDKIFMIHNGKIIASGTPQSLKEESGVNNLRDVFIKLARKEDI"
     gene            38118..40178
                     /locus_tag="KRH23_001137"
     CDS             38118..40178
                     /locus_tag="KRH23_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit/CPBP
                     intramembrane protease"
                     /protein_id="HHS5224426.1"
                     /translation="MRSKIVKYIFKKEMLDILRDKKTLFMMIVVPLLLYPLLMLLMIQ
                     VMNMSASSMNSKDINIAFNNKPNKVLVSMIEDDNLEKDTKNTSNDKGKIRVLDVDNYK
                     KSLEENKIDAYIKMEEKKSSINYQIYINSSQENSSNALKRIETVLDKYKRFTIEKTLS
                     EKGLDVQATLEPITYSTVDVAKTEEVAGYFLGQILPFILIIGVLLGSIYPAIDVMAGE
                     KERGTLETLFTLPISNLELVMGKYMAVSLSAIVTAILNILSMGLTMAFILVSGGISSQ
                     FGFGNFNYGDLVLPIITTLICICLFSMVVSAISMCVCSLAKSFKDAQNYITPLMLIIM
                     IPSYVSMIPNIVLDRVTAVIPVVNISLLIKSVLSFKSDLNLIALVLASNVAFVILAII
                     LLSKMFNSEEILFGNSKSFSFLEKRSNIKKGSIPTVSDGVILYAVGLVLLIYVGSLVQ
                     IKFGMAGIIMTQFMIISLPLLFAYYIKADFKEVFSLKVPKLKHVFGSIVLWIGGYILI
                     MIITQLILFLFPQNMEVAESLNKALFIKDSVLLNLLAIALLPAICEEMFFRGFIFSSF
                     SKSKDKNKSIKLAIICSGVLFGIMHMDFIRIIPTSILGIIFAYSVYKSGSIFVSMLLH
                     FLNNSVAVVLNHYTTGNITNLYKFVEVDFSNLNVLKFALILLISLILIMLGLRVLDRK
                     SLRN"
     gene            40860..42404
                     /locus_tag="KRH23_001138"
     CDS             40860..42404
                     /locus_tag="KRH23_001138"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0052621 - diguanylate cyclase activity
                     [Evidence IEA];
                     GO_function: GO:0071111 - cyclic-guanylate-specific
                     phosphodiesterase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="HHS5224427.1"
                     /translation="MRNLQKKLMFFLFICIILQITYTTPVYSLFKLYKNNSINNFESI
                     VSNNQLISKHAIQIILIMAIICVILIFYIIYDKLNFKIKLQRIAYTDNLTGANTIDKF
                     VIDANKILCKNTQVKYALLYIDIDKFKYINDLFGYEVGNEILRNLTKIIKSNIFEEEM
                     FARISADNFIIIMKYIEEEDITKRLKTIFEELDLFNNNQEEKYKLVLSCGIYFILPED
                     RDINSIIDRANIPHKMAKGGHKSSYAFYDNKIHDQEIKEKEMENTMFSSLENKEFIIY
                     LQPKIELNTGEIQGSEALVRWKRPDKGLIPPNEFIPFFERNGFVINLDLYVLEEVCIY
                     LRKWIDAGINPVTVSVNVSRIHLYCNNFIETYKNIIDKYNIPAKYIELELTESIIFDN
                     FDILIDIMNNLKKIGFLISMDDFGSGYSSLNMLKEIPMDILKLDQKFIMETYNSKRSK
                     IIVTKVIEMAKELGMKVISEGVETEEQFKLLKEVKCDMAQGYLFGKPMPIEEFEHLIV
                     SNLVRG"
     gene            42580..42948
                     /locus_tag="KRH23_001139"
     CDS             42580..42948
                     /locus_tag="KRH23_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HHS5224428.1"
                     /translation="MEWELDNNKPIYIQLVEHLKLKIISGEIKIGSKLETVRALAEDA
                     EVNPNTMQKALTELERQGLVYSQRTKGRFVTDDKEKIKAMKEEIANVEINTLKVTLEK
                     LGYDRDEMLKLITENLKGEL"
     gene            42950..43675
                     /locus_tag="KRH23_001140"
     CDS             42950..43675
                     /locus_tag="KRH23_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHS5224429.1"
                     /translation="MDKNISNVSQDGIVEFKGVNKSYGTKNVLKNIDLNIPKGKIVGL
                     LGPNGSGKSTMIKLMNGLLQPDNGEIMINGMKPSIDTKKIVSYLPERTYLNDWMKVSD
                     LLKFFYDFYSDFDVRRANEMIKSLDIDVNEKLKTMSKGTKEKVQLILVMSRNASIYIL
                     DEPIGGVDPAARSYILKTILKNYSEDSTLLIATHLISEIENICDEIIFISKGEIVLQG
                     DVEAIREEKGKSIDALFREEFKC"
     gene            43669..44433
                     /locus_tag="KRH23_001141"
     CDS             43669..44433
                     /locus_tag="KRH23_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHS5224430.1"
                     /translation="MLGKLLKYELKASGRIFIPLYIAILIVAVFNGIFMNTNILQVQG
                     IGILVLTSLFMALGVLTIVVTIQRFRKNLLGDEGYLMFTLPVSTSSLILSKCITALIY
                     AVLSFIVAVFTFGVLMLFGTSGILLPEILDLFNTSFKWISENFLDILLLVVVMFISYS
                     SFILLLYTSISMGQLPKFNKHRNIVAFASFIAINIVISIVGDAVGSILPNEDTNMVYH
                     LYQSPSFMLAILGSLVVAIALFFATKFILDKKLNLE"
     gene            44655..45905
                     /locus_tag="KRH23_001142"
     CDS             44655..45905
                     /locus_tag="KRH23_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HHS5224431.1"
                     /translation="MKSYTKAKWSVWGIITFSFVLVLFLRMSTAVVSDNLANELGFNS
                     IQISNIASFCLYAYAFMQIPAGILIDKYGARKISSLGIIMASLGSILFGLIQSIELAY
                     ISRVIVGAGTSVILLCILKIQGRWFNKSEFASATAKFSFVGNLGGVLATFPLVFLSEL
                     VGWRNSFLLIGIIGVVIGCFMYIIVRDTPKEYGFNVDTEPYEKSEKVNLVDGIKSVIK
                     NKSTWYNSMIMFSFVGLTSAFISLWGVRYIMDVYGVSKSFSAFIVSFFTYGFIFGSII
                     MDFVFAKIRSSKFNIIKFGAMIDLFIWIVIVVVYQVKPPIIVLPISFFIMGCIVMSHL
                     QVFNDAKYKNKEIYSGLATSVINTFEFIGSGIINLIIAISLQVNSYNIVDGYKKGFVV
                     FIVLSIITIVSSHIGVKNDDFKAI"
     gene            46096..46980
                     /locus_tag="KRH23_001143"
     CDS             46096..46980
                     /locus_tag="KRH23_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008381 - mechanosensitive monoatomic ion
                     channel activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HHS5224432.1"
                     /translation="MDTTKIDDISKLDLNNLDINKMDMGGIMESLLEWATTSGVKLII
                     GILILSIGFKIIKKFVNHVMLLLSKRDIDLTLRKFLKSLLLSVLKVAVIIIVLEYWGM
                     SLSSFAAVIASAGVAIGLALQGSLSNFAGGFIILLIRPFKVGDYVEAAGHGGTVEQIG
                     LFYTQLVTPDNKQILIPNGSVSNDSLINYSAKNTRRVDLTFSVGYEDDILHVRRVLKD
                     IVNNHKLIINEPEPFIGVVEHGDNAIKFATRVWCKTEDYWTIYLDLLEEVKVRFDEEG
                     ITIPYPKMDLTVKELNKI"
     gene            47342..47959
                     /locus_tag="KRH23_001144"
     CDS             47342..47959
                     /locus_tag="KRH23_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HHS5224433.1"
                     /translation="MCKKTYLLVVSMLIAGLLTACSGSPTKDSGQAQDNTKKEANASN
                     NALKDEKNNENLMEQDFKVPYTDAINIFKDKYKDADIVDLSLERDLNKFVYTVEGVDD
                     NNEYKMKIDANTKDVLEDKTEKLDSEDLNGVARKEKLDLNDIIKPQQAMEIALKEQNG
                     MVKEWSLDKDLDVTFYKIRIDKDKNEYDIKVDSKKGTVLKVEKED"
     gene            48067..50598
                     /locus_tag="KRH23_001145"
     CDS             48067..50598
                     /locus_tag="KRH23_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FprA family A-type flavoprotein"
                     /protein_id="HHS5224434.1"
                     /translation="MSLKSLKIKENLYWVGSLDPDLRVFDIIMYTPYGTTYNSYVLKG
                     TEKTVLFETVKDKHFDNYIERLNDLNIDFEKIDYIVVSHTEPDHAGSVEKLLDLAKNA
                     KVVASETAIKYLKEIVNKDFEYVAVTDGDTLSIGDKTLEFFSVPMLHWPDTIYTYIKE
                     DKTLVTCDSFGSHYSNDKIVNTLDENEEKDYLDALRYYYDCIMGPFKPSMVTAIEKIK
                     DLDIDTVCPGHGPVLTENPRKIIDLYYNWSVNEQIKLEKEVTICYVSAHGYTKIMAEA
                     IKAYIEKNSNYKVNLFDVIEHKQEDILAKIAVSQGVLFGTPTILGDALKPIWDILISL
                     NPVLHGGKVASVFGSYGWSGEGIENAMERISQLRMTAVKPFAVNFKPSNEEIDKLHSY
                     TGKFLDKLNSTFGSKKKTKKFKCVICNEVFEGDSAPSVCPVCGAKEDQFIEVEEDEVT
                     FRKDTDEYFVIVGNGAAGFYAADAIRKRNKTCKITMISNEDELTYYRPALSDGINEEL
                     GSDFYMEDKDWYDKNNIVVILGTNVDKLDEVNKTIIVNDGAIKFDKLVIATGSRNFIP
                     PIKGHDLENVFTLRNIKDLYSVKEALEKSKKVVVIGGGLLGLEAAWEFRLKGLEVVVV
                     EAMDSILSKQLDKEGSKILEQCVRDTGIDVRLGVAVDGIEGDGKAQKVVFKDGDSVDC
                     DMVVFSIGVRANTQMVQDTSVKIDRGIVVDKTLQTNIKDIYACGDVAQVGNISLAIWP
                     SSVEMGKIAGANASGDNLTFESEVYPVSLDAMNVKVFSIGNIQNFDKEISSKDEGQRI
                     YKKLFMKDGSLVGAILINDLSCTVKLIRLISEKGDFEDIMKADIL"
     gene            51032..51733
                     /locus_tag="KRH23_001146"
     CDS             51032..51733
                     /locus_tag="KRH23_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin resistance response regulator
                     transcription factor VanR-G-Cd"
                     /protein_id="HHS5224435.1"
                     /translation="MNENILIVDDEKEIADLIEVYLKNEGFTVYKFYTGKEALECIES
                     KNLDMAILDIMLPDIDGFHICQKIREKYYYPIIMLTAKIEDIDKIMGLTIGADDYITK
                     PFNPLEVVARVKTQLRRYMRYNNSYEQQSIIVNEYDIKGLIINKETHKCSLFGKEVAL
                     TPIEFSILWYLCEHQGKVVPSEELFEAVWGEKYLDNNNTVMAHIGRLREKIHEPSKNP
                     KFIKTVWGVGYTIEK"
     gene            51783..52865
                     /gene="vanS"
                     /locus_tag="KRH23_001147"
     CDS             51783..52865
                     /gene="vanS"
                     /locus_tag="KRH23_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin resistance histidine kinase VanS"
                     /protein_id="HHS5224436.1"
                     /translation="MRTALMAFIAIIFIWILYSFILYGKFSIWIVSFFENAFRMEYKA
                     ALNLYQQIFRNSMELFMILAMVIVFFIIFRVYLNWFTKYFSEINQGIDSLIKEDVGEV
                     ALSPELLAIEKKINSIKHILEQRKFETQMAEQRKNELIVYLAHDLKTPLTSVIGYLTL
                     LRDESQISEELRKKYLSISLDKAERLEDLINEFFEITRFNLSNISLEYSTVSLTRMLE
                     QLTYEFKPTLMSKNLKYTLNVTPNMMIRCDVNKMQRVFDNLLRNAVYYSFEDTTIEIT
                     AVQEDDYIKLKFINYSNTIPEEKLERIFEQFYRLDTSRNSNSGRAGLGLAIAKEIVEL
                     HNGTITAHSENNIITFKVIIPIVGNL"
     gene            53126..54226
                     /gene="vanG"
                     /locus_tag="KRH23_001148"
     CDS             53126..54226
                     /gene="vanG"
                     /locus_tag="KRH23_001148"
                     /EC_number="6.3.2.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-serine ligase VanG"
                     /protein_id="HHS5224437.1"
                     /translation="MNNKKIAVIFGGNSTEYDVSLQSAFAVLENLNTEKYDIIPIGIT
                     REGNWYHYIGDYNNIQNNTWFERDTDIIPVIVSQNRVKNGIIEFLIPDAVSQNHIPNS
                     AIESCENDIKYTKLDFVFPVLHGKNGEDGTVQGLFELAGIQVIGCGTLSSALCMDKDK
                     SHKLVHSEGIKVPKSILLKYSDKFNVAELSKDLTYPLFIKPVRAGSSFGISKIYKKEE
                     LQVAVDLAFEHDNEVIIEENIDGFEVGCAVLGNNDLLVGRVDEIELSKGFFDYTEKYT
                     LKSSKIHMPARIDLDCEKRIQETAKIIYRTLGCSGFARVDMFLTPSGEIIFNEVNTIP
                     GFTSHSRYPNMMKGIGLSFEEILDKIIEVYIK"
     gene            54223..55029
                     /locus_tag="KRH23_001149"
     CDS             54223..55029
                     /locus_tag="KRH23_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HHS5224438.1"
                     /translation="MMNNILLDKNKEDKMTNTILLTKDKVYDGNLILVNAFLPVKTSE
                     DIDLIPVDTRFPSILMKREATNILQNILKSICGINEIVPVSGYRTAEEQQDIYSSSLR
                     DNGKDFTKKFVALPNHSEHQTGLAIDLGLKKEVIDFICPEFPYNGICNEFRKAALHYG
                     FIERYQCKKEEITGISQEPWHFRYVGYPHSEIINKMNLALEEYIEYIKRFSYTNCLKI
                     EDKEKIIEIFYVPIHTKEEVRISIPEQCVYQISGNNKDGFIVTFWRNRKD"
     gene            55047..57185
                     /gene="vanT"
                     /locus_tag="KRH23_001150"
     CDS             55047..57185
                     /gene="vanT"
                     /locus_tag="KRH23_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine racemase VanT catalytic subunit"
                     /protein_id="HHS5224439.1"
                     /translation="MIRNKSYAGLDYFRIIAALLIIAIHTSPLLSYSKMADFVLTSII
                     ARIAVPFFFMLSGFFLISTYNYNCNKLKSFLKNVLFIYGIAIVIYIPLNIYTGYFSMN
                     NLVPNIIKDIVFDGTLYHLWYLPASIIGASIAYFLVKKLGLKYSLVITIVIYVIGMFG
                     DSYYGFLEKIPLLKNLYGYIFEVSDYTRNGIFFAPVFFILGGIISNKSNYMSTKNSLI
                     GFLISFLLMLCEGMFLHKLGVQRHDSMYIMLLPCMYFLFTALTFLKGSRARLLRTSSL
                     IIYIIHPMMIVVIRMFSKIFGIQTVLVDNSLIHYIVVSIASFIASIIIILILKPLKKY
                     LKGEHKVNTNRAWIEIDLNNLEHNVKMIQKAMPEDCELMAVVKANAYGHSAFEVATCA
                     NQIGVKAFAVATIDEGIDLRRYGILGEILILGYTNPIRAKELHKYNLTQSVIDLNHAI
                     SLNKQKYNIKSHIKIDTGMHRLGFDVNDVRSILKAFKLKYLDICGIFTHLCVSDSLKD
                     EDVDFTNKQIECFYKLIDFLLKKGIKIHKVHIQSSYGFFNYPNLKCNYVRIGIALYGI
                     LSSPNDTTKLQLDLRPVLSLKSQVILIRKIQKDDSFGYGRVFIASRDSVIAILSIGYA
                     DGIPRNLSCGKSYVIINDCRAAIVGRICMDQLAVDITDIPNVEVGNTAIIIGRDNLAE
                     LSASEVANNSCSISNELLSRVGRRLNVIKK"
     gene            57499..58119
                     /locus_tag="KRH23_001151"
     CDS             57499..58119
                     /locus_tag="KRH23_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HHS5224440.1"
                     /translation="MQYIQELLDLTQNYWVLATIIGLLSAFIESFIPALPLVAIVTAN
                     AAIQGLFIGCLLSWIGSGLGTTSLFLLISRFNDSKLFNKLRNSKTEKAISWMDKQGFK
                     LLFIAYACPFMPGCLVTIASAFGKKDLKDFVPAMLAGKFVMFIVISYVASDIEGFITS
                     PLKIASFILLVFLSWKIGNRVNKNLENHNYDFHHKKHHNDKDDKMI"
     gene            complement(58285..58821)
                     /locus_tag="KRH23_001152"
     CDS             complement(58285..58821)
                     /locus_tag="KRH23_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HHS5224441.1"
                     /translation="MIKETHERGGYIFALLILPFINNLYLVKYDIAYKIVLIIIYIYF
                     AYLGSLFPDIDMRGSYISKKFMLIYKLFGSRFRHRGFTHSLIALLLIYSFFKSLTIFT
                     NNNIVFSCLSSGFIIGYLSHLCLDLITKEGIELFYPITINISLLPIKTNSKTEKFISK
                     LLNFIVIFLIGYQFYILL"
     gene            complement(58934..59638)
                     /locus_tag="KRH23_001153"
     CDS             complement(58934..59638)
                     /locus_tag="KRH23_001153"
                     /EC_number="1.15.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004784 - superoxide dismutase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006801 - superoxide metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HHS5224442.1"
                     /translation="MKKKILIPVIMSLFIISQCITSFAFTPENNKFKVKPLPYAYDAL
                     EPYIDKETMKLHHDKHYQAYVDKLNAALEKYPELYNYSLCELLQNLDSLPKDIATTVR
                     NNAGGAYNHKFFFDIMTPEKTIPSESLKEAIDRDFGSFEKFKQEFQKSALDVFGSGWA
                     WLVATKDGKLSIMTTPNQDSPVSKNLTPIIGLDVWEHAYYLKYQNRRNEYIDNWFNVV
                     NWNGALENYKNLKSQD"
     gene            59811..61685
                     /gene="asnB"
                     /locus_tag="KRH23_001154"
     CDS             59811..61685
                     /gene="asnB"
                     /locus_tag="KRH23_001154"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HHS5224443.1"
                     /translation="MDGNISIYYKGDISKKEDIKFKIKESVNNTRLSSRIEYKDEEKT
                     FDFERFNVIDAIYGNKPFEKDGKVIVFNGNIYNYHEIKEELIKKGHNFTTNDDIEVLL
                     ASYIEFGKNCVHKIKGMFNFIIYDRENESIFGARDLFGIKPLYYINKENAIIFSSEYK
                     FLLEYMKNLNINERSLQSYFSFQYVLPEDTMIQGIRLIPAGHYFRVENGILSLKRYNK
                     LEFRSSTKFFYTKNHLGNRDVNEDDIRNIVVDSIVTHMEEEKEIGTFLSGGIDSSIIT
                     TVASQINPNIKSFSAGFSVKGYSELEVAKKTADKLGIENIQINITQDEYIKSLPNVIY
                     SLDDPIADPSEVGLYFLIKEAGKHVKVALSGEGADELFGGYNIYKEYSTMKSVVNSPT
                     YIKSILGRVSELMPNIKGRNYLYRATTPLEKRYIGNAKVFENSEVKRFFFKYKEKNIY
                     EYLLSNLYRDAQKNNYDYISKMQHIDVNTWLQGDILQKISKLSTAEQVELRVPFLYKD
                     VFDVAKNLRMEQKINKNNTKVLLREAFREIVPEHVVQRKKLGFPTPIRVWLKDSLGDI
                     VKETIYNSNVDEFIDKKYAIKLLDTHLKGHRDNSRKIWTIFTFCLWHQLFIEHKNVEY
                     "
     gene            complement(61777..63213)
                     /locus_tag="KRH23_001155"
     CDS             complement(61777..63213)
                     /locus_tag="KRH23_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HHS5224444.1"
                     /translation="MICTIKPLKISIKKSTEPLIEFISDTTYKNKRSSYIKEVYFTRY
                     IGVDDSIDKYIEKIKNIDTYFFNNPTIPYIRLNNLKINFDKEQTDKMLKIFNIYNSSK
                     FNSWDLYNIDFPCKIENDTLNWTKKIAFKNTLDLFSTSMPNCTSSIIKNFAVKLLCWM
                     DYFLPKLFYNKVKTTISPKIVYFGNIKRQELFFLYFLSQLGCDILYINPNKDILDLYP
                     ECSKFSTLFELSRKTPNILEIPFERHITNINYSENTNKTSPTTNKPNSKNTLNNTNLT
                     SKKIVQDEEVELSYEDLAKLSASVVMIIVCNNENKPFKSGSGVVINNEGYILTNLHVV
                     NDGYSFLVRFENDDKVYTSYQIIKYHSDYDLAVIKVDRKCKPIPVKVSKKPVRGQKIV
                     AIGSPLGLFNTVSDGIISAFRDFETVQMIQFTAPISSGSSGGALLDMFGNLLGLISAG
                     YDDGQNLNLAVESSLVKIFANNFIEIVN"
     gene            63542..64120
                     /locus_tag="KRH23_001156"
     CDS             63542..64120
                     /locus_tag="KRH23_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006950 - response to stress [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HHS5224445.1"
                     /translation="MGITLSKGQKVDLTKGNPGLKNILVGLGWDTNKYDGGFDFDLDT
                     AAFLTGASGSVTNDGDFVFYNNLKHTSGAVEHLGDNRTGEGDGDDEQIVVDLSKIPGE
                     ISKISFTVTIHDATERRQNFGQVSNSYIRIVDKDTNEELIKYELGEDFSIETAIVVAE
                     IYKHNGEWKFNALGSGFEGGLAALCGNFGINL"
     gene            64159..64737
                     /locus_tag="KRH23_001157"
     CDS             64159..64737
                     /locus_tag="KRH23_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006950 - response to stress [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HHS5224446.1"
                     /translation="MAIVLKKGQKIDLTKGNPGLKNIKLGLGWDTNSFDSGYDYDLDV
                     SVFMVGESQRVEKDEDFIFYNNLKHPSGAVEHLGDNRTGEGDGDDEEILVNLETMPKH
                     IQKIAVTVTIYEAAERRQNFGQVSNSYIRVLNSENDEEILRYDLGEEFSIETAITVCE
                     IYKYNGEWKFSAVGAGFEGGLEALCRNYGLNV"
     gene            64823..65452
                     /locus_tag="KRH23_001158"
     CDS             64823..65452
                     /locus_tag="KRH23_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006950 - response to stress [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HHS5224447.1"
                     /translation="MSINLSKGDKIDLKKSNPGLSNILVGLGWDPVQQSGGGFFKSLF
                     GGGQADIDCDASVFMLNQEGKLSGIKDLIYFGNLKSACKSVLHTGDNLTGEGTGDDEQ
                     ILVNLDKVPSNIHKLLFVVNIYNCVDRKQHFGMIENAYIRVEDQGNKKEIAKYNLSDN
                     YSEKTTLIVGAIYRKDGSWQFKAIGEGTKDAGLKEVMQNLDRIECAYGI"
     gene            65442..68201
                     /locus_tag="KRH23_001159"
     CDS             65442..68201
                     /locus_tag="KRH23_001159"
                     /EC_number="7.2.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005388 - P-type calcium transporter
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006816 - calcium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="calcium-translocating P-type ATPase, PMCA-type"
                     /protein_id="HHS5224448.1"
                     /translation="MEFNNDIKYYNVDKEEVTKDLSVNPEKGLSESEVKTRREKYGLN
                     EFTPKEEGSFWDDLKESLSEPMIVILIIAAVVSAVIGETHDAIGIVGAIAIGIAIGMI
                     TEGRSKKAAEALSKLTENIEVKVLRDGEVHQISKSELVPGDIVYIETGDMVPADGRLI
                     ESINLKIREDMLTGESDDVSKKCDVVVSMEEIESKGAVVVQEPIPAKQINMVFGGTLV
                     AYGRGALVVTSIGDNSEMGKIAQNLSETDEQTPLQIKLGNLGGLIAKVSSAVAGLLFI
                     FMVFQMISKNVLNVDMSGILPFLESIDPVKTAFTVCVALIVAAVPEGLPTMINMTLAI
                     TMQKMAKINALVTKKEACETIGSVSVICSDKTGTLTENRMTVEVAYVDGRYIESSEEE
                     INSYFEENCMINSTADVEHNDGDIKYLGSATECALLLYYKNVDYRQVRKNSNIVAQNP
                     FTSDSKRMTSVIGQDNHHVLLSKGAPEVLLELCSHIQRGKDIVPLTENIKHEILEEIK
                     KLQIKSMRTLGFAYKEISQAEEEAAVTAESDAMNVSAMENNLVFSGFVGIRDPLRKDV
                     IESVNTANKAGVSVKMLTGDNINTARAIGEELGLLKNNMRVVEASYIDTLDDEELKQE
                     IQSISIVARSKPDSKMRIVSALQKSGDVVAVTGDGINDAPALSKADVGIAMGISGTEV
                     SKNAADIILTDDSFSTIVKGIKWGRGIYDNFQRFVQFQLTVNVIAFLVAIISQVMGQE
                     MPFTTIQLLWVNIIMDGPPALALGLEPVRDHVLNRKPVDRKANIISKSMVYTIVLNAF
                     YITAILMLQSTFNFLGVDEAHKGTVMFALFAFSALFNAFNCREFNADSIFPNFTHNKL
                     ALQIIVLTGIAQVIFTQLFQDFFNSVAMDFMTWVKVLCVAASVIVVNEVVKCIIRLVK
                     PKKTA"
     gene            68288..69850
                     /locus_tag="KRH23_001160"
     CDS             68288..69850
                     /locus_tag="KRH23_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YceG family protein"
                     /protein_id="HHS5224449.1"
                     /translation="MGDSKVFEKIFSSQSDRGNYTPSKGYLSYFISYIGLEDEVLYNL
                     EIFKTKQNIDSKKDIALFTDVIANPSDFDIINYFKSGLQKYRTSMEDVDINILGFEEI
                     DYKIKQAMDRVLKEEEKEFTNDRVKQNFIVKIMAWIKIYIGALDINKNEAPKVIFYGD
                     IKKHEVYLLLILYLAGFDVLYLNPNSKSNINILKSERYNIEFEEANIIEEKISFEERV
                     ILGEKIDKSSVKKAFTVGAEASKRISEELLNDAGFIKPWQLQDRKIKNLLLSSTVDEI
                     SIYWNQPLKLRPGFKFNDAIVEAPNFLSKINGIYNDKNEYIKFLDLLRDSESSTFIEF
                     NGDVDRFSKAFTREAFSLSFLLDSKGAIDKNSVLNNKDYSISTLALNQQIMILEKVEE
                     LLEGSMFLNGLSGEDKIKGLFTVLHMDKKFVHMMNNFDYSLINPKLIIYMYKSIVFDK
                     EIVFLMLLLSKIGFDIIILCPGGENNIENVINNQLIDVHRLDKMVYDLKLNSLENDIP
                     LLKKIFGKRRRF"
     gene            69851..70987
                     /locus_tag="KRH23_001161"
     CDS             69851..70987
                     /locus_tag="KRH23_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HHS5224450.1"
                     /translation="MGININSFSKDKNSVEVTENLPTAVQEENFDIMEYTNNKKNELR
                     KSKEVEALTSLIEVENPDTILQFGRKASEGVARVSDSLLNTIKLNRNEENSKMLVHLT
                     KIMDKFDLDDFQETKEPNFVQKLFKKANNAIEMMFQKYETLGGEVEKIQIELEQYERD
                     IALSNKQIGAMLNENFEFYNELQKYIVAGEMAIEEMDNEILPFFKQKSETSGDQMDVV
                     NYQELLKVYDMLNQRVYDLRIAENIAIQTIPMLRGMQHNNYGLIRKINSAFVVTLPVF
                     KQCLSQAILLKKQELQAKSLKALDDKTNELLLRNAQNVSTQSAQIARMAGTSSVQIET
                     LEKMYNTIKSGIDETMRIEENNRALIKDNTKRLEELNTTIIYNK"
     gene            71051..72127
                     /locus_tag="KRH23_001162"
     CDS             71051..72127
                     /locus_tag="KRH23_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HpcH/HpaI aldolase/citrate lyase family protein"
                     /protein_id="HHS5224451.1"
                     /translation="MKYFDYICKDDLERIFLKEPEDFSAKTEKDVLKYALGAFLYVPA
                     TQYNMIYKSIIGDVKGVRPLAICLEDAVGVNGELEAIENLRLILKNISNESITNKDGI
                     PLIFVRIKDVEQLLRIKEIIIKNSHFITGILIPKANSELIENCIEALDSMNLQDMYVI
                     PIVETKEFIYNEKKELSFTNLYNAILRHKSRILSIRVGITDILGMYGIRRDKNFSIYN
                     NLICSSFILDIITYLQRPELDIPISGGVSEFFDMTNKDIRNKYIEEILLDKYHGLIGK
                     TVIHPMQIQIVQALSTVSYEDFTDALDILDSTDSKYGVSKGVLGERMNETNPHFLWAK
                     KTLILSKIYGVLNKGVDYEELLKF"
     gene            72105..73343
                     /locus_tag="KRH23_001163"
     CDS             72105..73343
                     /locus_tag="KRH23_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosyltransferase family protein"
                     /protein_id="HHS5224452.1"
                     /translation="MKNCLNFNCEIDIIDNPLNLELNDFLDVGIRNNSKRRFLFISKK
                     LGKHLACKPSEMDNLGKLMATIYNEKNKEESNGTVIAFAETGTAVGHSFFDYLCGDYE
                     FIHTTREQFDELENLEFLEEHSHATDQNLYFGMLNNFKFGDEIILVDDEITTANTCMN
                     IIRKIQSIYPKKKYTICSILNWVSDENLSKVTRLERELDCKIDFVYLFKGNFKFYIDE
                     DIISNYNDNYSITKLETISSDKVNLVVNHIYVDLEDYIGNKKYVKYTGRFGINRREQF
                     RLKEIVKRESKKITMASKESLKNEKEKILFLGTEEFMYIPMLFAKEKENQYDIYYHST
                     TRSPIINIDKKHYPIKSKFMLKSFYNIDIQNYIYNIDKHNFSKCYLFVELNKSENSYL
                     EFIDIIKKTSIKELTIVCCS"
     gene            73397..74485
                     /locus_tag="KRH23_001164"
     CDS             73397..74485
                     /locus_tag="KRH23_001164"
                     /EC_number="3.4.22.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine protease StiP family protein"
                     /protein_id="HHS5224453.1"
                     /translation="MRDFSTYSKDDVIFLLKDISNLIEEEGNKERELKIQNGRHYSEM
                     IPIEYEVSEDYLNLYHEKLRENKDKLAFSIGVMCEKIIKKNGNDVVLVSLARAGTPIG
                     ILAKRYIRSKYNISLPHYTISIIRDKGIDMNAIEYIVKNHPSSKIQFLDGWTGKGTIS
                     KELEKACDELNVKFKKYFDSTLAVLADPAGYSGLYGIREDFLIPSACLNSTVSGLVSR
                     TVLREDLIGKNDFHGAKFYRHLKDKDESMNYIETIEECFKNQFKNISDEVENWESDII
                     TRDGYFDVLNIKEKYNITDINFIKPGVGETTRVLLRRVPYKILVKDLNDKSLDHIFIL
                     AKEKNVEVEQMDLKAYKCCGIIKNMKDI"
     gene            74513..75304
                     /locus_tag="KRH23_001165"
     CDS             74513..75304
                     /locus_tag="KRH23_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase family protein"
                     /protein_id="HHS5224454.1"
                     /translation="MIVFSDLDRSIIYSNKFLNADSKYANIEIYREKEISYISLDTIN
                     LIKQIQYYGMFIPTTTRTVEQFKRIEFNKYGIYFPWSITSNGGVILKDNEILKSWSEK
                     IDKLKSDYEPIESMIHKFKDYLNVDGITNFKVAEDTFFYIVVDLSRFNLDSIKEYTNI
                     LESKNWKFYVSGRKIYFIPKEISKENAIKYLTKELGIEYFYAVGDSIMDYGMLNISNK
                     SYVLKHGDINKNEIENSFISSSFNGMSGTEEILSNILDENCLLNI"
     gene            complement(75419..75973)
                     /locus_tag="KRH23_001166"
     CDS             complement(75419..75973)
                     /locus_tag="KRH23_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HHS5224455.1"
                     /translation="MNIDVGSKIRSLRKSKNISISTLAKNSDLSTGLISQIERNMVVP
                     SIVAMWKISKALDINIGYFFEEIGREDSDIVVKKNNRKKIVTNDSTKFYELLVPNLSG
                     KKIEFILVTLDGHTQKNSEFVTHEGEECGYIIKGKMKITLGNKEYLLEEGDSFYFNST
                     IPHVYENYDDEVCISVWAMTPPSF"
     gene            76169..77371
                     /locus_tag="KRH23_001167"
     CDS             76169..77371
                     /locus_tag="KRH23_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF819 domain-containing protein"
                     /protein_id="HHS5224456.1"
                     /translation="MKSFVSPDNIWVLWAVVTGWAAFSIYLEQKYNWASKVSGAIIAL
                     VGAMLLSNLNIIPVESVVYDQVWGYVVPLAIALLLYQCNIKKIWKESGRLLIIFLVGS
                     VGTVLGAMIGFLALKNVVPDLNIVAAMMTGSYIGGNVNFAAMSGAFDAPGELVSATVV
                     ADNLLMALYFFVLIAIPSIGFFRKHFKHPHVDEMESIGITEGETVAANYWGRKEISLK
                     DIAIAIGSAFIIVAVSVELSTWFKAIIPLSNPFLAMLNTLFGNQYLIITTLTMLFATF
                     MPNFFGDIKGAQELGTFLIYIFFVVVGVPASITLIIQKSPLLLLYCGIMVLINMLVTF
                     IVAKIFKFSLEEAILASNANIGGPTTAAAMAISKGWSKLVGPILIVGTFGYIVGNYFG
                     LLVGNILI"
     gene            77447..78427
                     /locus_tag="KRH23_001168"
     CDS             77447..78427
                     /locus_tag="KRH23_001168"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0070573 - metallodipeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HHS5224457.1"
                     /translation="MIFDGHSDTWADVTIRRLNGEKDVFRRIHLDNFKRANIEGAIFV
                     IWIDPPYDKEPEKRVKQIISSIKDEIEDMKDVVNIVKKYSDIDKGISENKINILIGLE
                     GLSHIGRNIDLLDYFYKEVGARHASLTWNEQNELATGCLGDENRGLTEIGKKAVNKME
                     KLGMIVDVSHLNEKSFWDLMSVASKPVIASHSNARSLCDAKRNLTDNQLKEISNTGGL
                     VGINSFRGFTNSNPKKQDLIHLVDHIDYMVNLIGMEHVSFGFDFSDYLGKETIGSFTG
                     NASVPSVDGLESTHTAQNIVVELENRGYKKKDIELISSGNFYRLFKDILK"
     gene            78675..79628
                     /locus_tag="KRH23_001169"
     CDS             78675..79628
                     /locus_tag="KRH23_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHS5224458.1"
                     /translation="MKKRYLVIGIIILSYFSLFIGAEDINIMHIFAKNQHKLMIFIMS
                     RIPRLISILIAGVGMSIAGLIMQQISKNKFVSPTTGATIDAAQFGIVICMLLVPTASI
                     FTKTIIAFVFSLVGTFTFMKIIGKLQFKNIIFVPLVGIMFGNIIGSMTDFIAYKYDLS
                     QNVSSWMQGDFSMILKGNYEILYITIPLIILAYIYANKFTVVGMGMDFATNLGLSYKR
                     IVNIGLIIVALVTVCVVVTAGNIPFIGLIVPNIVSLYMGDNIRASIWYTGLLGAIFVL
                     ICDIFGRIIIYPYEISIGLTVGVIGSILFLYLILRRNVNEA"
     gene            79618..80574
                     /locus_tag="KRH23_001170"
     CDS             79618..80574
                     /locus_tag="KRH23_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HHS5224459.1"
                     /translation="MKLSLNQKIYFVSILLFISIALFIIYGIDMNHLEYALSQRIPKI
                     FAMVLGGGCIAFTTVVFQTITNNQILTPSVLGLDSLYVMIQTIIVFIFGSSSSLIINE
                     NYNFIINVAMMIGASLLLYKTLFEKNKNNIFFLILVGMIFGTLFKSATTFIQVMIDPN
                     EFLALQTSIMASLNNINTNVLLIAFIIIIAIIPFIYDEIKYLDVLSLGKEQAINLGVD
                     FDKAVKKMIILIAILVSISTALIGPMTFLGLLLANITREIFKTYKHTYLISGSMLIGM
                     ITLIIGQFFIQHVFKFDTTLSVVINFIGGIYFIQLLLKGANR"
     gene            80571..81326
                     /locus_tag="KRH23_001171"
     CDS             80571..81326
                     /locus_tag="KRH23_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHS5224460.1"
                     /translation="MIEIKNIFKRYKNKNVVDDVSFSIEKGKITSFIGPNGAGKSTVL
                     SIVTRLIGGDGGEVIIEGKSLTNYSNKELAKKIAILKQSNNITLKLTIRELVGFGRFP
                     YSEGNLTKEDENYIDEAIEYMKLTDIQHKYLDELSGGQRQRAYIAMVIAQDTEYILLD
                     EPLNNLDMNHSVQMMKVLRSLCDELDKTIVLVMHDINFASCYSDNIVALKNGKVEKVG
                     RTDEIVNEKVLEDIYEMNFNIKNINGNRICIYF"
     gene            81418..82383
                     /locus_tag="KRH23_001172"
     CDS             81418..82383
                     /locus_tag="KRH23_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HHS5224461.1"
                     /translation="MNKKAAIVAAVAIIGLVTVFALGGSKKNESKTSENSNNTMKITH
                     NLGETDVKLNPKKVVVFDYSALDTMDALGVAENLVGLPKASLPASLEKYKDDKYADLG
                     GLKEPDLEGIKSANPDLIIINGRQEDFYEQLSKIAPTISTSKDDKKYLESVKNNIDKI
                     AKIFGVEEKANQEFSKIEKKIETLNKKVTDKNLNALTIMVNEGNLSVFGEESRFSILY
                     NSFGFENKDKNIKESSHGQNITFEYIAKQNPEVMFVIDRGIATGSDVKESSTAKSVLN
                     NDIIKSMDAYKNDNIIYLDSPTWYVNDGGLTSLNKMIDDASKAVN"
BASE COUNT        32016 a         8701 c        14197 g        27658 t
ORIGIN      
        1 ctcggattta taagtttaaa tataaaaaat aaaattttaa aaaagtattg acaattgatt
       61 tagaagggtt taaaataaat tacaacataa taaataaaaa ggcgatgaat aggaagagta
      121 aatctaattc gattaccaga gagaagagtc cgttggctgg aagacttttt aaattagagg
      181 gattgaaaac tacctaggag ctactttctg aagtcatctg cattagtaga ttttagtaag
      241 aatagtcgtt agctgcgtta aagtgtaaag tgagttttca tgacatatga aaactaaatt
      301 aggtggaacc gcgggaataa tactctcgtc cttatgttat aaggatgaga gttttttgtt
      361 atttaaaaat ataaacagta atcataataa ttatagaaaa tataaaagca atgaatagga
      421 agagtaaatt taattcgact atcagagagg aaagttcaca ggctgaaaga ctttctaagt
      481 ttgagaaatt gaaaactacc taggagctgt ggtctgaagt tactttaaaa agttttagta
      541 agactaaccg ttaactgcgt taaagtgtaa agtggatttt atcaataaat gataaaatca
      601 aattgggtgg aaccgcgagt atagactcgt ccctttatat agggatgagt ctatttttat
      661 tgcaataaaa gattgaaaat aaaaaaaaat cggaaaattc taaatttagg aggaaaataa
      721 aatggagaat aaagtgaaaa ttggagtact aggatatgga gttgtaggaa gtggacttat
      781 agatataata gataataata aagaaaaaag aaatatagaa atagttggaa ttttagttaa
      841 taatttggaa aaacataagg ataaaaaata ttctaatata ataactaata atatagatga
      901 tatatttaat aaagatatag atatacttgt tgaagtcatg ggtggtttag aaccatcatt
      961 atcttatata aaaaaagcat taaacaataa aattcatgtt gttacagcaa ataaagattt
     1021 gttagctgaa tgtggagatg agcttgcaaa attagcaagt gaaaataaag taagtattaa
     1081 atttgaagct tcagttgcag gaggtatacc agtattaaaa ccaataatag aatcactaga
     1141 aggaaataat atagatagta taaatgcaat tttaaatgga actactaatt ttatattatc
     1201 taaaatgtat gatgagaatc tatcttatga tatggcatta agacaagcac aagaattagg
     1261 ttttgctgaa gcaaatccag agtcagatgt attagggtat gatgctgcta gaaaactatc
     1321 aatattatca actctagctt atgacaatag agtatattgg aaagatgtgt atttagaagg
     1381 aattacagat atagatgaaa aagatattga atatgcaaaa aaattaaatt gtaaaataaa
     1441 attgattggt caaagtaagt atgaaaatga taaagtaagt gcttttgtta gacctgtttt
     1501 agtagaaaaa gataatatcc ttgctagaat agacaatgag ttcaatgctg tcatagtgaa
     1561 tggagattca gtaggagaag tttcttttgt aggtaaagga gctggaagtt tagcaacagg
     1621 aagtgcggtt tattcagatg ttatagatat aatagataat agagtttcaa gtatagattc
     1681 ttttactaaa gataaaatac aagttaataa aatagttaga gaaaagtgtg gagcacttct
     1741 tagatttaaa aaatgtaata aagatgaaat tctaaatata gttgagaatt gtttagtaaa
     1801 attcgatatt ttaaatgatg atgatgaact tgctattatg gtttatgctg attctgaata
     1861 tgaaataaac aacagtttat gtctaataaa agataaagga tactgcgaaa aaatgaataa
     1921 aatgttgaaa ataagttaaa aaagaaaaaa tataagttta tatgtaacat attttgacga
     1981 ttttaatact atatagtatg agatgaaaca aaacatctca taaaaaaatt aaaattaaag
     2041 ggagagatat gttatatgga aaataaaaaa tgttattcag aagattggta tgaaagagga
     2101 gaatctacag ctaaatggtt ccaaaatgat agagaagaat atgaaagaga agcatatgat
     2161 gaagatagag aaagaagagg ttcaaactgt ggatgttcag attcaggaga aaatagacct
     2221 agaaactgtg aaagatttag aagagaagct gagataagag aaagagaagc aagagaagca
     2281 ttctgtgaat cttcagagaa aaagaaagag gcattagcat atgaatgtga agctagaaaa
     2341 ttatgggaag aagcagaaaa atactgggat gaatattcaa aatacaacta taaaggaatc
     2401 gaatatttag cagaagctgc tagattattt gatgaaggta tggaatgtga agctagaaga
     2461 aatggaaata atggaggaaa caataataat tgttgccata aatgccataa atgtaattgt
     2521 aactgctgta gaaaataaaa aaattaattg acaaatcaat agttaaaata tatcatatta
     2581 tgtataataa agagaaaatt cagaaaaaaa taatgattag aagaaatata agtatattta
     2641 ttagacaaat agtgctcagt tagtgaggtg agtacaatat gattaaactc ccatcctcta
     2701 gcttttgata gagggtggga gtttttattt atttatatat cttaaatgag gataatattg
     2761 taaaataaat gagtatgaga ttgtaaaatt aggaggtaaa aaatgaaaag tattaaaaca
     2821 tcaagtatga aagaaaaggt agatgaaaag atattaagag agcaagtaag ttctataata
     2881 gaagatataa gaaataataa ggatgttgca cttaaaaaat ataatgagaa gtttgataga
     2941 aatacaagag atgaatttag aattactaag gaagaaataa aggaagctta taagcatgta
     3001 gatgacgaat ttataaataa cttaaagatt gctgccaaaa atataagaga atttgctaaa
     3061 gctcaaaaac taagttttga aaaccctttt gaaaaagaaa tttatccagg tgtaatctta
     3121 ggtcaaacta atattccaat agagtcatgt cttgcatatg ttccaggagg tcagtatcca
     3181 ttgttttcaa cagctcttat gcttataata cctgcaaaag tagcaggagt aaaaagaata
     3241 gtggcatgtt caccaactat gaaaaatact gaaaagataa atcctaagac attggtagct
     3301 atggatatag caggtgctga tgaaatatat gcaactggag gagttcaagc tatagcagca
     3361 tttacatatg gaacagaaaa gattaatcca gttgacataa ttgtaggacc aggaaataag
     3421 tttgtaactg aagctaaaag acaatgttat ggacaagtag ggattgattt tgtcgctggg
     3481 ccaagtgaag ttcttataat agcggatgaa acttcaaatc cagtttatat tgcagctgat
     3541 ttattagcac aatgtgagca tgatttaaat gcaagaggaa tattattgac aaatagcttg
     3601 gaagtagcac aaaaagttga aaaaaatata gaaagtatgc taaaagattt gccaacaaag
     3661 gacatagcat atagttcatg ggaaaataat ggagagataa tattggttga tgatatggaa
     3721 gaagccatta aaataagtaa tttttatgca ccagaacatt tagaagttgc agtaaatgag
     3781 tataatgata tttgtgatag attaactaac tatggttctt tatttattgg aaatctttct
     3841 gctgaggtgt ttggtgacta tgtttcaggt accaatcata cattaccaac acttaaagca
     3901 tcaagatata ctggtggtgt ttgggttgga acttttatca aaacttgtac aaagcagata
     3961 tttaatgaaa aagctataca atcattagca cctgtagctg aaaagctggc aaaagaagag
     4021 ggattatatg cacatgcaaa ggctgctgag gttaggttta aaaagtagta aaaaatttta
     4081 ttttggcagt cgagacttag tattagactg agataaggaa aacgctgaga acctgaataa
     4141 atactatatt ttgtgggcct cggcgtttct tttatatctg tatataatag aataatacta
     4201 tctgtgtgtt taaatactaa cttaatattt cttttctaaa taatgtttat gaaatagtta
     4261 atatttttag ttaatagttg aaaaaaactt ttgctaactg tgcaaattca tctgcatttg
     4321 tcaatatagc agggtgtcct ccctgactaa aaatgtgaat acttgctttt gaaataaaag
     4381 ttgccatttg tttgtactct tcttcaagat tatgacgaca catttcgtct tccttacttc
     4441 ctgtaaataa aattggcatt tctaatttac acaattcttt atgaaacaaa gggcgtttct
     4501 cgtttgcaca ttgcaataga gcttttgtat caagattaac aacattctcc caatcttttc
     4561 cctgacacca ttcatagaat tttcttgctt gaatatcttg ctttgatttt tcccttccag
     4621 tgattagatt atctatgaag ttatcattaa gagtacgtcc atcaaagcta tctgctataa
     4681 ttgcttcaac taaatcggga cgttctaatc cagtattaac agctgcccat gctcctccac
     4741 ttgttccaat taagccaact ttaccacaat tcaaatgttc aatcagtgct attgtctgta
     4801 aggcttcatc atgccatatg tcaggagaaa attgagaaac tctatccgac tgtccattac
     4861 ctaaaaaatc aattaagata catctaaaat tttctgcata taatggcaca agtgctttaa
     4921 acatattaga agaaccagta ttaccatgca ggaaaattat cggtttacct tgtccatatt
     4981 ctttataaaa acaagaatta ccttgatact gaaaatatga catatatttt cctccttttt
     5041 atttgttaag ttaattataa caatataggt atgaatgaaa aacctcatgt tctttcttag
     5101 aataaaaatg tgccacgcat aaaacgtgac acatttctaa ttataaattt tgctgtttaa
     5161 gtattctttg tatgcttttc tctgtcaaaa agtatttctc tgataactgc ttgatactca
     5221 ttccattttg gaaatttata cagatttgag aattacgaga agctaagact tgtttggtgt
     5281 ttgtgttttc accccaatgc tttttgtgct cttgcttttt gggaatataa atcactttac
     5341 catctatata ttcttgcact tgctcaatca gttctttagg cagtaagtca atcgaatttt
     5401 gatagctcat tttgcacctc ctaaataatt attctttagg attagcaaag gctactgcca
     5461 ctcacaatta aaaataaaat tttttattat gtacaatagc ctttgctatg cacaagttcc
     5521 aattcccata aactaaatac tcctttctgg tttgaaaaat tcatctgaac attgatttcg
     5581 cttttaagat agagttcaat gacaaattta catttttatt atatatattc agatagataa
     5641 ttgcaactgt ctttgtatga ggatatttta ttatagtcaa tactataata tgtatttata
     5701 tcatcaaact aatatgaaca gttgaaagga atatgaacaa taaaacttag tcaggaagaa
     5761 taattatgaa gcagacaata gagaaatttg attttaaagt tttattgaaa atttattgac
     5821 aaatttaact tgtaaatatt atactaaact taataaataa agtttataaa gtaaggtgtt
     5881 gtctatgaaa aatatagttg gaaaaccgca aacgataaaa aaagtaaatg aagatttaat
     5941 aaaaaacatt ataaaaaatg aaggtcctat aacaaaacca gaaatttcaa gcattactga
     6001 attgagttta gctacagtta ataagattgt agagcaatta gctttgaaaa atgaagttaa
     6061 agtaagtgga ctaagtgaat ctactggagg aagaagagct caattatttg aaataaatgc
     6121 aaacttagaa cacataatag ctttatatta ttatagaaat tgttgtatag gggtagttgc
     6181 caatttatta ggtgaaataa tttatcaaga agaatttaat ataagaatgg atacgtatga
     6241 aaacgttaac caagatactt tttttgttat agatactcta ataaaaaagg aaaaaggaaa
     6301 caatataagg gctattggaa ttggtgtccc aggagttgta aaaaaaggtg tagttaaaaa
     6361 tataccaact ataaaaagtt gggaaggtat aaatttagaa aatttaataa agagtaaata
     6421 caatactaaa gtgtttatag aaaatgatac aaatattact actattggga tttatcaaaa
     6481 acagtataaa gacaaatata aaaatatggc tcttatgtat ttagaagatg gtattggttc
     6541 aggtatagtt ataaatggtg aattgtattt aggttctaca aattttgctg gagaattaag
     6601 ttatctaaat atagaatttg gtaagtataa ctctaacaac ttaaatcttg aagattatat
     6661 tatgagttta agaaaaagat atttagaaag taaagataat aaatttaaga aagaaatttt
     6721 atctataata tcaaacttta taaggactct tgtatgtgtc ctaaatccac aagctatgat
     6781 tatacagtgt agtatattaa ccaagagtga catggagttt atagaaaaag atgtaagcaa
     6841 taatgttgga gaagaaaatt ttcctaaatt aataaaagta gactcattga gagaaggaag
     6901 tataaatgga gtaattagta tgtgtttaaa agaaactgac tatcaatatt ccttatctaa
     6961 taaaaaagga ggatattaat gtgaaatatt tggtttcaat agatggaggg ggaacaaaaa
     7021 ctaaattttg tgtaagtgac ttagatggaa acatacttaa agaacatacc actggttcaa
     7081 ctaattataa gtcagttgga attaaaaaaa catatgaaaa tattaataat ggatttaaaa
     7141 aaatattaaa agatttatat atcgattatg acgatattga gtacactgta tttggtatat
     7201 ctggttgtga ttctcctaat gattataaga ttataatgga tgaaatatta aaaattggga
     7261 ttaacaaaga aaaaatatat ctggcaaatg atgcagtttt agctttttat gcacaagcgg
     7321 attcccctgg tttagtaatt gtggctggga caggttcaat tatactggga attaaagaag
     7381 atggagaaat atatagagtt ggtggatggg ggtataattt tagtgatttg ggttctggat
     7441 atgatatagg gagaaaatta ttaaagaaag tattgcttta ttgtgatgaa tgtcatgagt
     7501 atagtgattt atttagttgt gtcttggatt tctttggagc gaatagtttt gaacaacttg
     7561 catatatgat tactgatata aacaataatg ttgaaatagc aaacttagct tcattagtga
     7621 ttgattgtgc cgaacaaggt gataaattgg ctattgaaat attaagagaa tcatcaactg
     7681 aactatctaa attagctcaa gtaatattga gaaaaatatc taatccaatg aaaatggata
     7741 aaagcgaaat aaatatagtt ttgtctggtg gtacattaaa taaaactgta tatgctcaaa
     7801 tgttaatgaa taatttaaaa acagaaaata cagataaaaa tttaaaattt atatctcaag
     7861 aaaatcagcc agtgtatggg gggataagac ttgctatggc attagctaat aggagggtca
     7921 agcatggata gaaaaaaggt aatagtacaa atttttactg gaggttttaa ggctaaagaa
     7981 ataaagttta atgatataaa atgtaaacta ctagaattat tggactgtat tgatatagaa
     8041 aaggttatca tgggatggag tgtagatgaa gaattatatg tagaaactaa aaaactatta
     8101 aataaatata atgttgaact atatctttgg ttgccatgtt tttctgaaat aggattactt
     8161 gaaaaaagta atttactaat tgattatatg gggaaggaag tcaagggcta tgctttacaa
     8221 gaggatgaaa attttgagtt ttattgccca aataataagg aaaatataaa aaatataaag
     8281 aaaatatata gtacttattt tagtgatatt aaatttgatg gaattttttt agataaaata
     8341 aggtatggtt ctttttcgaa taaactaaat ggtgttttta attgtttttg taaagattgt
     8401 ttaaatatat atgaaaaaaa taatattgat aaagagtcgt taatgagaga aatgaataat
     8461 gtgtctaagg gagttataga taatgaagat gctccatttg gtataacaga atacattaat
     8521 ggaaaataca aatttaaaaa taaaatatgg gaagattttt ttgaaacaaa aaatcaaaat
     8581 atatacaagg cattattaga gataagtagt tattttaaaa gtaagggatt gaaaataggt
     8641 atagatactt tttctccttt tatttcttac tttacaggtc aagatttaga aaaattacaa
     8701 gaagtagcag attttataaa accaatgatg tatagaacta caaaagctcc agctggttta
     8761 ccatttgaat ttgaaaggtt tattgatgaa tccatacata agaataaaga gattggaaaa
     8821 agaaatttct tagatatttt aggaattaag gagtatgaag gagatgtata tcctatagaa
     8881 tttgtactag aggaaatcga ttttatgaca agaaatctta ataaagatat atatgtagga
     8941 gttgaaataa ataaaaagga aattatatct cctgttacac ctaagtacat aagtgaaaat
     9001 atttcaaata taaataagac aacagtaaaa ggatatgttt tatcttggga tttgttgtca
     9061 gcaccaaaag aaaatattga tgaaattata aaatggtttc ggaattagtg aggtgataaa
     9121 gtgagtaaga tattggaaat gcaacaaata tataaaagtt ttggaaaggt agatgtttta
     9181 aaagggataa attttgagtt agaaaaggga gaagtaagag ctcttttggg agctaatgga
     9241 gcaggaaaat ctacacttat taaaatttta ggaggagttc attcccaaac taaaggtaaa
     9301 gtaattttga ctggtaatga aataatgttt aaaaatccac atcattctaa agaaaatggt
     9361 attagtataa tttatcaaga attaagcttg ataccaacgc ttacagtact tgaaaatatt
     9421 tttcttggta gagaaatttt aaaaggaagt gtgtttttaa acaagaaaga catgcttgag
     9481 gaatatatga aaatttgtga ggattttgat tttaatatag acccacatat agtagtttct
     9541 aatttaagtg tagcaaacca acaaatggtt gagataatga aagctgtttc atgtaattct
     9601 gaaattatca taatggatga acctacaaca tcacttacta ataatgaaaa agatgggcta
     9661 tttaaaataa taagtagact aaagtctaaa ggtaaaacaa tagtctatat ttctcacata
     9721 ttagaggaag tttttaaagt atgtgatagt gcaagtataa tgaaaaatgg aattatgatt
     9781 ggaacttatg atgtagagga tttaactaaa ttaaagataa ctcaacttat gacaggaaat
     9841 gataatcaca aacttattga gaagaaggat tatacatttg caaaatatga agagccacca
     9901 gtactagaag taaagaatat aagctggtct aacaaaataa aaaatgtttc atttaaagtt
     9961 tatagaggcg aagttgtagg tcttgcaggt cttgtaggtt caagaagaac tgaaattata
    10021 aatttgatat ttggtataga taataaagat agtggagata tttttatcaa tggtaaaaaa
    10081 gtagacataa tttctcctaa ggttgctata aaaaacaaaa taggattgat tcctgaagat
    10141 agaaaaaatc taggattaat tttagaacaa gctatataca caaactcatc atcagtacaa
    10201 attgataaat tcaagaaatt cttgtttata gatagaaata aagaaattga gttttctaaa
    10261 aaaggtgtta aggaattagg aataaaagtt agtgatgtaa agcaagaagt aaaagagctt
    10321 agtggtggaa atcaacaaaa agtagtagtt tctaagtggt tagagaaaga tttagattta
    10381 ataatatatg atgagccgac aaagggaata gatattgctg caaaagaaga gattttcaat
    10441 acaatcaaag aattttcaag taaaggaata ggagtaatat ttatatcttc tgatttagaa
    10501 gaagtaataa gagtaagtga tagaatttta gtaactagag aaggttctat tgtagatgat
    10561 ttaaaaaatg agaatataca ggttcaagat ataatgaaca gtatatttaa tgtataaaaa
    10621 atgaaaatgg aggactgaga tgaagaaagc ttttgagaag ttaaatttaa gagattatgg
    10681 agtattatta ggttttttag ctttatgtat agctataagt attgcaactc catcattttt
    10741 aggtaaacaa aatatactta atcttttacg acaatcttct ataattggaa taatttcagc
    10801 aggtatgact tttgttataa tatctggaaa ctttgatata tcagttggag cagtagcagc
    10861 tcttgcaggt gctataacaa tgaaatttgc gactggtgga actaatttgt ttgcatccat
    10921 gctcttaggt gtagcgattt gtgcagtaat aggattaatc aatggtatag tagttgcaaa
    10981 gataaatgta ccatcattaa tagccactat ggctatggtc actattgtaa gaggattgct
    11041 gttgatgctt acaagaggat atccaattac tgaaaatata ccaatacttg attacattgg
    11101 aaatggatat ttgtttagta taccaatacc agtagtaatt ttctttatag tggtgttagc
    11161 ttcgtttatt gtacttaata aaactaagtt tggtagatat gtttattctg taggagggaa
    11221 tcaagaagca agtaaactta atggtataaa tgtagattct cacaaagtga aagtgtttat
    11281 tattaatgct gtacttgcag gaatagctgg aatcgtacta acaggaagac ttgggactgc
    11341 aactgcgatt gcaggtgaag gatatgatat ggatgcaatt gcatctgtag taataggagg
    11401 tacatcagtg gcaggaggtt ctggttctgt acttaaaact gttataggag tattacttat
    11461 gagtgttata aacaacagtt ttaatcttct tggaatagat gtatatttcc agtacatatt
    11521 taaaggatta ataattttag cagcagttgg atttgattct tatagcaaga aaaaacttgc
    11581 ttcaagataa aaaataaggg ggattttttt atgaaaaaat taatgaaaca tttagcattg
    11641 ttgctatcac ttgttatgat atttggttta gttggttgtt caaatggtgg tgacaaagaa
    11701 aaaaatggag aaaagaaaat agcagtatta ctaccaggtt caacaggtta ctttgtagca
    11761 actaaacaag gtatagatgc aaaatctaaa gaattaggtg taagcgtgga atatgcagat
    11821 gctcaatggg atgctagtaa acaattatca caagctgaag attttatggc taaaggggta
    11881 gacatgattg cattatgtgg agttgattct gctgtaagtg agagaatagt taaagctgct
    11941 aatgattcag acgttcctat agtagcattt acaaattcta taggaagtaa cccaactgga
    12001 gaatttaaag gtttagttac atatatagga caaaatgagg aagaaacagg agcattaact
    12061 ggaaaaattg ctaaaaactt attaggagaa actggtggga aagctgtatt aatagaagga
    12121 gtaccaggaa ctactccaca agtattaaga aaaaaaggtc ttgaaaaaga attaaaagat
    12181 agtaatatag aaatagttta taatcaaact tcaaattggg agaaagagca agctttaaag
    12241 gtaacagaag atttaattca aaagaaaact gattttaatg ttataatatg tcaagatgat
    12301 aattctgcta caggtgcagg tcaagcttta aaagatgctg gtcttaagga taaagttaaa
    12361 gtcataggtt tgggtggaag taaagatgga ttaaaagcta taactgatgg gttaatagat
    12421 ggtacaactt atatgtctgc tgtagaagaa ggtggattag tcatagaaaa ggcatctaaa
    12481 ttccttaaag gtgaaaaaat agaacctgtt acacaaatta aacaagttga agttaacaaa
    12541 gataatattt cagagttcaa gggtgaatgg taaattctca tagataataa ataagatttt
    12601 tagagttact ttagaaacta tataaagtaa ctcttttttt aatttaattt agtgataaat
    12661 tattgaatag tatttctaaa caaataaaaa attaatataa acaaagactt aattatacta
    12721 aattataagt aaaactaata taaacttatg gaaaaaagga aaacgtctaa agtattggaa
    12781 ttactatagt gtaggtgtag tattaaaaaa acataaaaaa acataaaaaa attgttgaaa
    12841 aaaatataga aattttgtat aattaaagat ttgaaaagtg cggtatacaa agccaattct
    12901 tttgtatata atatatataa attcagaaaa aggaagggat atgtatggcc aggcggttat
    12961 ttttagaaag gattggactt atatttttag gttcagcaat attagcattt ggagtttata
    13021 atttttatta tttaaacaac ataacagaag gtggagtgtt aggtatttta ctactgttaa
    13081 aaaatttatt caatatacaa ccagcaatag caaatgttgt aatagatggt ttactacttt
    13141 tagtaggata taaatttttc ggtaaaaaat tccttatata ttcaatagta gcttctataa
    13201 ctttttcagt gttatatgac ttatttgaag ctataggacc tctagtacca caatcacaaa
    13261 atatgctttt atcaactatt ttggcaggtg taactgttgg aactggtgta ggtatagtag
    13321 taaaagcagg ttgtgcatca ggaggagacg atgctttagc attagtaatt tctaagacta
    13381 catctttgaa catagggcaa gtttatttag caacagatgt tattgtattg ttgttatcat
    13441 tattttatct atcagcgttt gatatctttt attctttgat tgctgttaca attagtggca
    13501 aggtaattga ttttatttat tatcatggta aaagtttgga tatggatata agtaatgata
    13561 tagttccaga atgttaatat aaattaaata actttagatt ttattagggg tggcagattt
    13621 gccacctttt ttgtgtctaa atctttatag aaagtataat cccatctagg tttttgcaaa
    13681 tctcaaatat agaattatgt tggaatgact gggaatacga ttgctagatg tgcattttaa
    13741 aaaccaaatt ttatatttat gaaatactaa tcattaatgg atgtttctta atcctatctt
    13801 tatacctaaa atgataagat aaatgaagta gcaatacaaa gctaaaattt gtaaaagaga
    13861 ttaaattaaa tggaggagct aaaatgttgg atatagttat gatagcattg ttattcatag
    13921 gatttgtttc catgaagtta cttgctgatt ggtgtgggaa acaaactgaa aaaaaataat
    13981 gtaatgtatg gagggattac ctatgtggtt tctggcagtt gtaattataa tgttaataat
    14041 atatttggta tatgcgctta ttaatcctga aaaattttaa acagtataag gctaataagt
    14101 aagttgaatt ggggggaaca atttttatgg tgcagatagt aatagtgtta gcgattttta
    14161 tgattttagt aatacctatg ggcaagtatt tatatcatat agctactaat caaaaaacat
    14221 ttggagatag actatttgat aaagtggaca attttatata taaggtatgt agtatagata
    14281 agaaaaaaga aatgaactgg aaacagtatg cattagcttt attatttaca aatgcagtta
    14341 tggtatttat aggatatatc atacttagga ctcaaagtat gcatattttt aatccaagtg
    14401 gaattaaaag tatggaacaa ggactatcat ttaatacaat aataagtttt atgacaaata
    14461 caaatcttca acattattca ggtgaatcag gactttcata ctttagtcag atgacagtga
    14521 taatatatat gatgtttaca tcagctgcaa caggatatgc ggctgctatg gcatttgtaa
    14581 gaggtctagt cggtaaaaag aaaacattgg gaaattttta tgtagattta attaggataa
    14641 caacaagagt acttttacca ggagctttaa ttattgggct tatattagtt acacaaggag
    14701 taccacaaac ttttgctggg acagaaacag tgactactat agaaggaaag cttcaagata
    14761 tagctagagg tcctgtggca gctcttgaat caataaaaca tttaggaaca aatggtggtg
    14821 gattctttgg ttcaaattca tcacacccat ttgaaaatcc aacaataata tcaaatatag
    14881 tagaaatatt atctatgatg atattaccag gagcttgtgt tgttgcattc ggtcacatga
    14941 taaagaataa aaaacaaggt tgggttgtgt ttggcgcaat gtcaatcata tttttaatag
    15001 gtctagtagt gtgctttaaa gcagaaagtg caggaaatcc tattttatca caattagggc
    15061 ttaatcaaag tatgggaagt atggaaggta aggaagttag atttggtata gcacaatcat
    15121 cattattcac aacagtgact acttccttta cgacaggtac agttaataat atgcatgata
    15181 cactgactcc tttaggagga ttagtaccac ttttaaatat gatgctaaat gtagtatttg
    15241 gtggtaaagg cgtaggtctg atgaatatgt tgatgtacgc tataatagca gtattcttat
    15301 gtggattaat ggtaggaaga acaccagagt ttttaactaa gaaaatcgaa ggaaaagaaa
    15361 tgaagcttat tgctttactt attatattac atccactttt aatactaatg ttctctggtc
    15421 tttcagtagc aataccagca ggacttgaag gaatttcaaa tcctggattc catggattat
    15481 cacaggtatt gtatgagttt gcatcttcag cagctaataa tggttcagga tttgaaggtt
    15541 taggagataa cactatgttt tggaatataa caacaggtat agttatgttc tttggaagat
    15601 atgtgtctat tatagtacta ctagcaatat caagtttgtt agcatctaaa aaagctgtaa
    15661 atgaaagtat aggaacactt agaacggata attttacatt tacaatagtt ttagtacttg
    15721 ttgttttaat tgttggtgct ttaacatttt tcccagcctt agcgcttgga cctatttcgg
    15781 agcatctagt gttgtggcac taaaaaattg ggagggagta aagttttatg gaaactaaaa
    15841 aaacaaagtt tattacaaaa gatattttca aaacttccat tatagaagct tttaaaaaat
    15901 taaatcctaa atatatgatg aaaaatccag ttatgtttgt tgtagaaatt ggatttatag
    15961 taacattgat acttacaata gtacctagtt tgtttggtga tgaaggcaat aacttaagag
    16021 cttataatgg gattgtaaca ataatcttat ttataacagt cctttttgca aattttgctg
    16081 aagctgtagc tgaaggaaga ggtaaagctc aagcagatac acttaagaaa actagaaaag
    16141 atacagtagc aagggttata gatacattag gaaatgaaaa aatgataagt gcaagtgagc
    16201 taaaacttgg tgatattgtt ttagtaaatg ctggagaggt tatcccaaat gatggagaag
    16261 ttatagaggg tatagcttct gtggatgagt cagcaataac tggagaatct gcacctgtca
    16321 tgagagaatc aggtggagat ttcgcatctg ttacaggtgg tactacagtt gtaagtgact
    16381 ggttaaagat aagaataaca acaaaaccag gagaatcgtt cttagataaa atgatagctc
    16441 ttgtagaagg tgcttcaaga caaaaaacgc caaatgagat tgctttaaat actttattag
    16501 tagggttaac acttatattt atggttgttt taatatctct ttatccaatg gcaaactatg
    16561 caggtgtaaa gattccaatt tctactatga tagctctttt ggtatgttta ataccaacta
    16621 ctataggtgg attgttgtca gctattggta ttgcaggtat ggatagagta actagattta
    16681 atgtaattgc aatgtcagga aaagcagtag aagcttgtgg agacgttgat actatgattt
    16741 tggataagac aggtacgatt acttatggga atagacttgc atcagaattt atagcagttg
    16801 gaaatgcaga ttcaaaagat ttaataaatt attctgttat gtgttcatta aaagatgata
    16861 caccagaagg aaaatctata gttgatttag gtatgaaatt aggttcaaca ggtaagacaa
    16921 aagaggcaga ggaagctgag tttgtagaat tttctgcaca aactagaatg agtggtatta
    16981 acttagctga tggtagagct ataagaaaag gtgcttatga tagcataata aaaagagtaa
    17041 aagaatctgg tggtacagtg ccagaagatt tagaagaaaa tgtaaatcga gtagctaaac
    17101 taggaggaac acctttagta gtgtgtgtag ataatgagat atatggaatt atctacttaa
    17161 aagatacagt aaaatcaggg cttgtagaaa gatttgctag acttcgagag ataggaataa
    17221 agacaataat gtgtacaggg gataatccct tgacagcagc tacaattgca agagaagctg
    17281 gagtagatgg atttattgca gaatgtaaac cagaagataa aatagatgca ataaaaaaag
    17341 aacaattaga gggtaaaata gttgcaatga caggtgatgg aacaaatgat gctcctgcac
    17401 ttgctcaggc agatgtaggt cttgcaatga atagtggtac aacatctgca aaagaagcag
    17461 ccaatatggt agatttagat tcagacccaa ctaagatatt ggaagttgtt gaaataggaa
    17521 aacagctttt aataactcgt ggggctttga caacatttag tatagcaaat gatgttgcaa
    17581 aatattttgc gattatacca gctatattta ctcttgcaat acctcaaatg gagatattaa
    17641 atgtaatgaa actttctaca tcatttagtg cgatattatc agctttaata tttaatgcta
    17701 taattatccc atgtttaata cctcttgcaa tgaagggagt aaaatataga cctatgaaat
    17761 cacaagctat gttaatgaga aatatgctta tatttggtct tggtggagtt atagtaccat
    17821 ttttaggaat aaaattaatt gatttattga ttacaccttt agtaatggtt cttaatttag
    17881 gttaataaat ggaggatata aaaatgaaaa cattaaagcc agcattactt gtaagtattg
    17941 tattgttagt tgtttgtgga cttgtatatc cacttgtttt gacaggtgta agtcaagttg
    18001 catttaaaga taaagccaat ggaagtatga tagaagtaaa tggtgtaaaa gtaggttcag
    18061 aacttattgg tcaaagcttt acagatgcga gattctttaa gggaagagta tcatcagtaa
    18121 actataatac ttatacaaaa gaagatttag taccagataa agatggaaac acatcttatg
    18181 gaggtgtatc atcagggtct tttaattatg gagctacaaa tccagaactt catgatagag
    18241 tacaaaaaga tatagaacag tttttaaagg ataatccaac tgtcaaaaga gaggatatac
    18301 caacagattt acttacagca tcaggttcag gacttgaccc taatataagt ccagcctctg
    18361 caaaaattca gataccagct atagcaaaag cgtctggaat atcagaaagt aaattacaaa
    18421 aaattgtaga tgataatact tccaaaaaac tttttggagt tttaggtgaa gatagagtta
    18481 atgtactaaa ggttaatgta gaggtcgcaa aaatattagg tcttatatag tattttgtag
    18541 aattttagta acaaaatatt actcaagatt taatttaaag gttaaatttt aaagagtgaa
    18601 aatcaataat gattttcact tttttatttg aatattacta atatttggaa taaagtgatt
    18661 gtaagtataa aatccaaaaa aaggttgcat tatcaaaatg ataatactat aatatattta
    18721 tcgttatcaa tttgataata gatttggaca tataggagga aatagtatgt tatataataa
    18781 cgcattagag ttgataggaa acacacctgt agtaaggctg aataatttag gctgtactaa
    18841 tgggtgttct aacatatatg taaaattaga aaaagtaaat ccagcaggaa gtataaaaga
    18901 tagagctgtt tatgaaatgt tagagggctt agagcaaaga ggagaattaa aaaagggaga
    18961 tgtactagtt gaagcaacta gtggaaatac tggtattgca ttatctatga taggaaaatt
    19021 aaaaggatat gaagtagtaa tcgtaatgcc cgaaacaatg agcgttgaga gaagaaattt
    19081 aatgaaggct tatggagcaa atttggtgct tacagatggt aaagctggaa tggcaggttc
    19141 catagaaaaa gcaaatgaac ttttaaaaga aaatccaaac tataaaagcc taaaacaatt
    19201 tgaaaataaa gataatccaa atgcacatta taaaacaaca gcagttgaaa ttatgaatga
    19261 tgtcaaagat ttagatatat tcgtatgtgg agttggaaca ggtggtactt taataggaac
    19321 tgcaagatat ttaaaagaac aaaatccaaa tataagagta attgcacttg aaccaaaaaa
    19381 atctccagct atatcagaaa acaagactgg acctcataaa atacaaggaa taggtgctaa
    19441 ctttgttcct gaaaattatg attctagtgt agttgatgaa gtaatattag tagatgatga
    19501 agatgcattt gatacagtta aattacttgc agcaaaagag ggaattttag tagggatatc
    19561 ttctggagca aatatatttg gtgctataga gatggcaaaa aagtatccag ataaaaagat
    19621 agttacagta gctccagatg gagttgataa gtatatgtct atgggaatat tttaataatt
    19681 ttatttgagg gagtgaatac tttgtttaag aaaataaata aagatattga atatataatg
    19741 aagaatgatc cagcagctag gtctaagata gaagtttttt tactttatcc atcagttcat
    19801 gcaatgataa tgcataggat ggctcatgct ctttataaga agaagaagct ttttacagca
    19861 agattaatat cccagatatc cagatttatg actggcatag aaatacatcc tggtgctaaa
    19921 atgggggaag gtatattgat agaccatgga atgggtgttg taattggaga gacagctgaa
    19981 gtagggaata gggtgacaat atatcaagga gctactttag gagctacagg aaaagatact
    20041 ggaaagagac atccaactgt tggtgatgat gtattaattg gtgctggaac aaaaatacta
    20101 ggacctttaa atataggttc aaattcaaaa attggtgcaa attctgttgt cgttaaggat
    20161 gtacctaatg gtgcaacagt tgttggtata ccagcaaaaa tagtaaaaat aagaaaccta
    20221 gaacctgtaa aaaagaataa aaaagaagtg tcctatgagt atgatgaatt agataatgta
    20281 tattatatat aggatttata taactataaa ataaacttta taaaaattat tttaaaaggt
    20341 atttttttca aatttgagga cataataaaa aagaactgaa tgttacagtt ttggttcatc
    20401 aatctttgat aaacaagatt ttaaatttgt agcgtctagg aggattttat tatgaaagca
    20461 aatgttaatc aagatacttg tataggttgt ggattatgtc catcaatatg tccagaagta
    20521 tttgatatga aggatgatgg gaaatcacat gttatagttg atgaagtacc aagtgatgct
    20581 gaagaatcag cagcagaagc tagagaaagc tgtccagttg atgcaataga tgtgcattaa
    20641 taaaataaat gcctataaaa attgaatttt caatttttat aggcatttgt cttttattca
    20701 gttagtattt caacacctgt ttctgtaact aaaaccatac attcccattg agcagataat
    20761 ttaccatctt ttgtataaat agtccaatta ttttcttcat caacaaaaat ttcgtgagtt
    20821 ccttcattta ccataggttc tattgtgaat atcatcccag gaaccaatag catctcagtc
    20881 ccttttttag atacataact tacaaaaggg tcttcatgaa agcttaatcc aactccatga
    20941 ccacctattt ctctaacaac agagtatcca tttttctttg cataagagtt gatagcatca
    21001 cctatatctc ctaaaaatcc ccatggtttg gcaacttcaa gacctttttg gacacattcc
    21061 tttgtaactt gaactaattt ttttgcattt tcattaacgt tacctatcat aaacattctt
    21121 gaagcatctg aatagtatcc attaaaaata gtagaaacat ctacatttat aatatctcca
    21181 tcttttaaga taatgtcctt acttggaata ccatgacaaa cttcattatt tactgatgta
    21241 catacacttt taggaaatcc attatagtct agtggagcag ggatagctcc attttgtagt
    21301 gtaaagtcat gaaccaactt atttatatct tctgtagaca ttccaatttc gattttatct
    21361 gaaatataat ccaaaatttt tgtgtttatt acagcacttt tttttatttc ctcaatttga
    21421 ctttcatttt ttataatatc atgagttggt acaatatgac ctaacttagc aaatgaatct
    21481 attttattat ccatatccat atgacatttt ttatattttt tagtacttcc acaccaacag
    21541 ctatcatttc tatttaactt cataactttt catccttctt ttattattta tttaaattat
    21601 gggttacata aactatttta aaacataacc attataaata ttataacata aatactaaga
    21661 aatcctttat agatagtgat ttattcaaag tataaattat tatatggtta ttgttgatga
    21721 aaagaggata gttaaatgta ttattggata ttagcgcact taatagttta gttcaagttt
    21781 ttcaagaaaa tcatatgtta gaggacaatt ttcctttaaa gtattttttg aatcttcatc
    21841 aagataataa tgtacaaatg attctgcaaa aaattcttct ataaacttgc ttatatatgc
    21901 atgtgcaact tgcttagggt cataaagctt atatctttcc tgagcaaata cttccataaa
    21961 ttcttcagaa tttgattttt tatttaaaac atttttatct atagcatgtg cagtttcatg
    22021 taattctaaa ttttttgatg aatgtacatt tgcatagcta gggttactat aacctatttt
    22081 agccactata gaattatttc tatatatacc aggtacatct ttccaagtct tgcctgatct
    22141 tacccaacat ggaggtaatt gatattttaa atcactaaat tctggttcat cagttagatt
    22201 tgaatttatt aattttattt ttatatcctt ttctttaagt gtctgtaaat atttaatatt
    22261 tatttttgca agtctgtttt tcatattttc aacttcatct ttatcataat tcaagtcatc
    22321 aggaagtata agcatttgtt caattatatc tatactactg tcttttatat tttcagattc
    22381 ttcattaaat ttatattgaa gagtattatt ttcatagata gttatatttg tattattttc
    22441 tatagaataa gagtgaatat cctctaaatc taaaatattc atttgttgta aaatatgttt
    22501 tgtctcgcca ctccatacta ctaaagaaag tgaattaaaa ttaattagtg gattttcttt
    22561 tgcttttata tcattgctta tatctacatc aaatacatat tcaattgagt cttctatgtt
    22621 aagactatct gtattctttt taatatataa atacgcttgt tttaagtcta tataaatctc
    22681 atctaaagat tcgtcataaa attctgataa attattagta aagagttctt cacttaaaag
    22741 ttcattttta tcagttatac tttcaattaa aatattaatt tcttttatca tatcgtaaat
    22801 acttattttt ctatttgctt tttcactaga tacattgcat ggcgcaagag caatgcaata
    22861 aaaatctttt tcttttttat aaaaggcttt aagtgatttt gataaaagtg taaagtctac
    22921 acctatctgt aagttgacct taagtgagtc attttgtaat aattcagtat tatttctttt
    22981 agctgtattt aaattgtttt ccataatcat tgcccccttt ttattagggt atcataattt
    23041 ttttatatgt gtcaatttgt ttttttgaaa attttatttt ttataatttg tgaatttttt
    23101 attatagaaa taaatatgtt attattatgt caaaatttag cattagattc atgtagagta
    23161 tgttttatac atatattata attaattctt tgaagattgc atattcaaaa tacacaccat
    23221 tttttttaat tctataatat aatatttata tatttaatgt taggatgtga tttaaggtgt
    23281 attttacata tattataaga tgtaaagatg attctctata cactggatat accagtaata
    23341 tagtcagaag aatgaatgaa cataagttag gaattaattc aaaatacaca agagcaaagg
    23401 gatttgaaaa actagaagtt tattttgtga ccaacacaaa aagcaatgct atgaagttag
    23461 aatattatat aaaaaaatta actagaaata aaaaattgtc tataataaaa aacccaagta
    23521 tacttataaa tttaattgat aataaagaag attatattat tggtaaggaa atagaacaat
    23581 taacataaat atttatagta acattataat gggtgcatat agtgtaaaaa cttgacaata
    23641 aatactattg taatataatg aagttataaa tatagtaaat taaaatagct aggggagcca
    23701 agagctgaga ggtataccga cccttacacc tgatctggat aataccagcg taggaaagct
    23761 tagtaaaaat tcaagtatgt attatttgtg atatatgcta tttctaagct atacctattg
    23821 taggtatagc ttttttaatt aagttattta aattaaactt taggaggcaa caatgagtaa
    23881 ttataaaata ccaacactta caatagctgg atctgattca tctggaggag ctgggattca
    23941 ggctgatttg aaaacgttta gtgcaattgg tacttatggt atgagtgtaa taacagctat
    24001 aacagcacag aatactaaag gagtttttgc tgtagaggat ttaaataaga aaataataaa
    24061 aaaacaaata gaggcagtct ttgaagatat acctccaaga gctgtaaaaa taggaatggt
    24121 ttcaagtcct gagattatac ttgaaatagt tgagaatcta aagaaataca atccaaaata
    24181 tttggttgtg gacccagtaa tgatatctaa aagtggatat tatctattaa agccagaggc
    24241 aaaagaaaac ttaattaagt atttgatacc acttgcatac ataattacac caaatatacc
    24301 agaggcagaa gaaataacag gaataaaaat acataatgta gatgatatga agagagtagg
    24361 agaagaaata ctacaacttg gacctaaatt tgtacttatg aaaggaggtc atttagatgg
    24421 agaagcagtg gatattttag ttggtaaaaa tatatttaaa gtttataaaa gtgaaagaat
    24481 tgataaaaaa aatacacatg gaacagggtg cacattatct tctgcaataa catcttatct
    24541 agcattagga tatgaaataa cagaagcagt aaatctaagt aaaatctata taacagaagc
    24601 aataaaaaga agttttgata taggtcatgg agtaggacca gtacatcatt tttataaatt
    24661 tgagtaataa aaaaatattg gaggtagaat atgtataatt taattaaaga tgtaaaaaaa
    24721 ttaaatccat tggtaattca ttatactaat aatgtaacta taaatgattg tgctaatgta
    24781 actttagctg taggagcaag tcctcttatg agtttttcat atgaggaagt agaagaaatg
    24841 gtaagtgtag caaactctgt agtaataaat ataggaacta tgaactcaaa tatgttggat
    24901 ttattcctat tagctggaaa agcagcaaat aagtacaata aacctgttgt tttggaccca
    24961 gttggagtat ttgcaagcaa agcgagagca gaacttacaa gtagactttt aaatgaagtc
    25021 aaatttagtg ttgttaaagg gaatgtatca gaaataaagt ttataggtgg ctttaatgta
    25081 aggggtaaag gtgtagattc atttgatgaa gaagaagatt ctactgagat aataagaaag
    25141 attgctgaaa agcttgaatg tgtagttgta gcaactggaa aaatagatat aataactaat
    25201 ggtaaaggta catataaaat aaacaatgga actgataaat taaaaggaat tacaggaact
    25261 ggatgtatga ctgctagctt gattgcaagt tttatggctg ttactgagaa tatattagaa
    25321 gcagcaacaa tgggtgttct tacaatgtct ttaagtgggg aattagctaa tttaaataat
    25381 ccaccaatag gtacatttaa agaaaatctt atgaatgcta tttatcaaat ggatatagat
    25441 actttaagta aaaattctaa tattgaattt ttaaattaat aaagagtaag ggagacttaa
    25501 aatgattgat aaagaatctt taaaaaaatg tttaaagttg tatttagtaa ctgactctga
    25561 aatgcttaaa ggtagagact tttataaatg tcttgaagat gcaatatctt ctggaataac
    25621 aactgtacaa cttagagaaa aaaatgcttc tggaagagag tttttaagaa aagctatgaa
    25681 acttagagaa ataactaaaa gatatggtgt taagtttata ataaatgata gagtggatat
    25741 agcacttatt tgtgatgcag atggagtaca tgtaggacag agtgacattg atgttagaga
    25801 ggttagaaag cttataggaa acaataaaat tctaggagta tcagcaagaa ctttagaaga
    25861 agctatttgt gcaaaaaatg atggcgcaga ctatttaggt gtagggtcta tattcacaac
    25921 atctactaaa ttagatgcaa aatcagcttc gtttgaaact gttaaagaaa ttaaagaaaa
    25981 agtagacatg ccatttgtac taattggagg tataaattta gacaatatag ataaacttaa
    26041 atgtttagaa agtgacgggt atgctataat atcagctata ttaaaagctg aagatatctc
    26101 taaagaagtg gaaaagtgga cattaaaaat ataaaattgg ctctggtagt gaaaaaaatg
    26161 gaaaaatttg atataatcta agagtaaaat ttaagcaatt ataaatgata aacttttcta
    26221 catatacttt ttaatcaaga tatatgtaga tttggttaaa aaggagctat aaatgattag
    26281 gatattgtta gtgtgtgttg gaggcatgtc ttctacccta ttggtaaata aaatggagaa
    26341 ggatgcaaaa aaaagaaata tagactgtaa aatatgggca gttggagaag gagatataaa
    26401 atcggagctt gataactttg atattttact tcttggacca caacttagat ttatgcttga
    26461 tgacgtaaag tctatagttg gagatagagc tccagtatct ataatagata tggtaaacta
    26521 tggcacttgt aatggtcatg ctgtgttaaa ttcggtttta gaaatattaa aataaataat
    26581 aaaagtggat tctatataat agagtccatt tttattattt gttattaata ggcttaaaac
    26641 ttagcttacc atttcttttt ttaatctcca catagcaagt gaaaaacttg aacagcacaa
    26701 tattaaaaat agtaggataa caggcagtat atctccaata agaatagtct caccaaatat
    26761 taagctacgt aaagcgttaa taacatgggt aaatggattg agcatcactg ctacttttaa
    26821 tcctccagat aaactttcta tagggaaaag agctgaactt aaaaagaaaa taggaagtac
    26881 aattgcagtc ataattgttt cataaactat ttcatttggc aataataaac ttatagaata
    26941 agctagactt gataaaaaga aggctgtcat aaatatcagt actatcataa gtaggattcc
    27001 accaatgcca gattctatcc ttactgagaa gaatatactt actatacaca aaatagttac
    27061 ttctatgaaa gaaactaaga tagcttctaa taattgacca aggacgattg aatacctact
    27121 gataggtgca attaagactc tatagaaact tccactgttc ttcattataa agtttataat
    27181 accaccacta ctacaagaag aaaacacaac cagtacaatg atacctggta gtataaaagc
    27241 agtataatta ttgatattta tattattcat agtttggttt gcaatagaac tataaagcac
    27301 aagccaaaga aaaggttgta atatagtaac tacaaatgag attggatttt taaaacgcca
    27361 cttcatacta cgccataaga tatttaacat tcccattcct cctttaagct ttttttagaa
    27421 cttgtaagtg ctaaaaatac atcttcgaga cttggctcta caatttctat tgcatcaaat
    27481 tctatatcat gttctaaaag ccatttattt attaaagtaa aagcagttct actatcgttt
    27541 acacttataa aaattgaatt ttctcgtacg ctcataaact ttactaaacc agtactttta
    27601 attgaatctt tatatttttt tatatcttca gtattatgaa aagttatacg tagtatattt
    27661 tgtctaatgt aactacgtaa acttgatggt gttccttgtg ctaaatcctt tccattcttc
    27721 ataatacaaa tattatcact caattgttca gcttcttcaa gataatgagt agttagaaat
    27781 atagttgtgc catactcatc tctaattttt aataacatat cccacataga ttttcttgaa
    27841 tcgacatcca taccaacagt tggttcatct aaaaatagga ttttaggaga tgataccata
    27901 ttcatagcta tgtccaatct acgttttaca ccccctgaat atgatgaagt aggatatttt
    27961 aagtaactag ataagtcaaa cttatcaatt aaagagtcta ttctttgttt tgcaatctgt
    28021 ggttctactt tatacatttt actttgaaat accatatttt ccataaggga taaatgttca
    28081 tcaatagaga tttgctgtgc tacacaagca atttgagtac gtatccaaga aggattatct
    28141 actaaatctt ttccaaacat ggttacattt ccagatgtag gtttgtaaaa ggtagtcaaa
    28201 atatttataa gagaagattt accagcacca ttaggaccaa gtaaagaaaa aatttctcca
    28261 gcatttacat taaagcttag accatttaaa gctttcacac catttttata ttcttttact
    28321 aaattgtcta tttcaatcgc taacatatat tattcctcct ctttaagtgg aaatattatc
    28381 tctgtaatat agttatctgg gtttcctttt atcaacatac ctggtccttt aataaatact
    28441 tctctccaag gagtttgtat ttttatatta ttttcatgaa tatatttaaa tatcatttca
    28501 tacgtttttg gcaaattact ataagagcct gtgtgagtaa aaaataaagc ttttgtttta
    28561 ggaaattctt ttgtagttat acccatacga tttggagttt cagcagttgg aacacataat
    28621 tccatttctg caacaccagt tttttggtca acatcatagt agcaaaagaa tggtgcaccg
    28681 ttagactttc cttttatagc tttaaataca tttggaaaat actttgttgc ctcagtcata
    28741 ggtccattat aacgcatggt agccactgtg actgattcga tatttttgat ttcaattttg
    28801 caattcattt gtttacctcc taatgtgtgt tcatattctt actagatttt taagcattaa
    28861 tacatataag attttgatta gttgaaaaca tataatctta tctcgtttgc ttgttttcaa
    28921 gtctaacata acataaaata tatatcctct catttgatgc tccattttgt aaagttatta
    28981 tttaagcttt actttagatt ttttagcaaa ttaaaataaa gcaatttata aaataagtat
    29041 ttacaaatta agtgtattaa tcgtataata cacttaatag gatactagat aaagtctgaa
    29101 ataaaggcgt atttttttaa agtaagtgta ctatcgtatt aatacactag aataggagga
    29161 atcatgaatt ttgaattaga taatacaact cccatttatt tgcaaatagt aaagtatata
    29221 aagagacaaa tagtaacagg agagttgaaa ccaggagaga caataccatc aagaagagaa
    29281 atggcactta atctaaaagt aaacttaaat acagttcaaa gagcatataa ggagatgggt
    29341 gatatgaata taataaatac ttttaaaaat tatcaaagca gtgtaacagt tgatgaaaat
    29401 atattaaaaa atttaaaatt agagcttata aatgaatcac tatctgtttt tatagaagat
    29461 atgaaagcaa taaatgttag caaagaagaa gttttaaaaa taatagaaga taagtattag
    29521 ttttttaaca aatagaaaac ttagtttaga aagtttattt ataagcatat tggatgtgga
    29581 ggatagtaaa tatgatagaa ataaagaatg tcagcaaaac atataaaagg atgcaagggc
    29641 ttaaaataag aaagatagaa gctttaaaaa atgtaagttt taatatagaa aagggaaaaa
    29701 taactgcatt acttggtata aatggtgttg gtaaatcaac tatgttaaaa gcaatagcag
    29761 gacttataaa cattgatagt ggagaaattc gtatagatgg agaaaaaata aatgaaaagg
    29821 tatacaataa attggctttt gttccagatg tacaatctca ctttagcaat acaacaataa
    29881 aagaaacatt tgaatttatg gaaatttttt attcaaagtg gaataaagaa aaatcaaaag
    29941 aaatgatgga catatttaaa ttggatgaag atgaaataat tgataacttg tcaaaaggaa
    30001 acattgcaag agtaaaatta atacttggat tttgccaaga cccagagtac atacttcttg
    30061 atgaaccatt tacaggaatt gatttgttta agagggaaga gtttatagga gtaatagcgc
    30121 aatatatgga ggaaaatcaa gccattatca taactactca tgagatagta gagatagaaa
    30181 gtttagttga tgaggttgta attcttgatg aagggcagat tataacttca tttaatgcag
    30241 aagaattaag agaaagagaa ggtaaatcta tattagataa gatgagggag gtatataaga
    30301 atgaataaac ttctatatct aataaatgta gatttgagaa gaagcaataa gttttatata
    30361 gcttatatat catttttttc attaattaca cttagtttaa atttattcga aattaataaa
    30421 tttaaaaatt ctaaatttat tatgaactta gcaatagaag attttggagg tatattttat
    30481 ggactaggga tacttagtaa tcttggtttt atccaaagta tattgttctt tgggatattg
    30541 ggacttttta tatactatat ttttatgtgg aaaagagagt tcttttcaaa taatcaaagt
    30601 atttatacac ttatgatgtt acctcaaaat aagtttaaga tttgtatatc taaatcaata
    30661 gccttgataa caatgatata tggttttttg ataagtcaga cagcaacatt atttatatgt
    30721 aaatatatat ttaatttcat ttttagaaat atgcctataa tcaatatgaa ctttgccaaa
    30781 gatttatatt atttaaactt gaagagtata ccaattgatt ttatctcttt tatggctatt
    30841 tatgtatttt tactacttat agctatttct attgtaaatt gctgtatatt atttatcttt
    30901 tcctatataa ataaatttta tgtaatttta atcactttgc tgattatagc aggcttatat
    30961 ttttcaacaa tatatataaa tataatcact ttatttagaa aatattataa tcttatagga
    31021 tttcaattta acaatttagt agcagggtta ttaagttttt taattataat gtttattcta
    31081 aatggaatat cttatttgct aattaaaaag aaagtatctc tttaaggagg ggtggtatga
    31141 aattaaaatc taaaatatct atacttatta tatttttgac tttagcaata tattttagta
    31201 taggtttatt aaataatgaa gataatttaa agataaaaac tataaaaggt gactctaatg
    31261 aattagacca tataaacata aattttggat atgttttgaa tggatatata aattcatatt
    31321 atacaataaa tggaagtaac aaaaccaaaa agactgaatt aataaaacta caaaaggata
    31381 gtaagaacac aaataattta attgatgtat ctagtggttc agatttaatt gcacatgttg
    31441 gatttgaaat gaatgaggag tcaaaagata taaactttgt aatagatgag aaaaaagaag
    31501 atttagaaaa aggtgtattt ccatcagaag gaagtgataa agaaattgaa tatgaaaaat
    31561 tagatatgaa taattttaca aggacaagat ataaagtaga taaaagtaca gatgattatt
    31621 atgcaaatat actagcatca aaaagatata aaaaatactt atatgtatct gtactttatg
    31681 ctacaagtga ttcatcagaa aataacaaag aatattcaag tactatagat ataataaaaa
    31741 ttaatccaga aaataaaaaa atcaagacta taaaaagtat aaatttaagt aattattttt
    31801 ccgaaaaata ccaaaacata gagaccatag gtgtaagtta tgctagcaaa tatgaggata
    31861 agatgtatat tttagtaaat gtactaaata caaacatagg tgataatagt aattctaaat
    31921 ttcatttact tgagtataat cttgaagaaa ataaggaaag cataatggaa ttaaaaactg
    31981 atagcaaaat ggctttagca aaagcaaagt tagaagctaa taaattatat atggtaatgt
    32041 cgaatgatta tgataatagt tcaattacag agttaaattt acttacctat aatatattag
    32101 ataaaagctt agatgaagat aaatatgttt tagataatag agaaaaaaga ggaattagaa
    32161 gtattgaaat tgattcaaat aaaatcgttg catatacatc aaggctaaac tctatattat
    32221 cttgggataa taaatttatg ctatatataa taaataaaaa ttctaaggaa attgtatatg
    32281 aaggagaatt acaatttaac agttcaaata gtatgttaga atttgaaata aagtaggtga
    32341 gttgatgaaa gatttaataa gattattcga atttgaacta aaaagaaata taaagaatta
    32401 tatatttata ataatttgtt gttgttcttt tgtaatttta aacatagtaa aaaatttaaa
    32461 tgactataat tacataatag aaaatgcagt taaaagtgaa cagttaacaa aaatcggaaa
    32521 tacgatagaa acggtaaagg ttacaggttt ctcaagcttt agaaatataa tgggttctac
    32581 agaatcgtgg tttatgtttg gtataattgc atgtatttgc tattcttttt ttatttggta
    32641 tagagacttt aatggtagga gtaaatctat atatacactt ataatgctac ctaaaaatag
    32701 aatcaatatt tatatatcta aattattaaa tatattattt ctagtgtata gctatacagt
    32761 agtacttaca atatctttgt ttattgcaag taagttgttg cctagacata tgcttggtaa
    32821 tgtcacaaac tatggttttg tacaagaaac aatatatgag ttaaaaatgt tacttccata
    32881 tagctttgaa atactatttg tagagtatat atttttattg ataggatttg tatctgtagt
    32941 atttacatca attcttataa ataaatctat ttataaagta agcactttaa taagttttct
    33001 atttttagtt atagaaattt tagtgtttat aatttctata gaatttatta taccctacga
    33061 atacagtgat gtatttactg ttctatattc aagtataaac atatttgtat gtagtcttat
    33121 atctaataaa cttttgaagc aaaagattga cttttaggag ggatattatg aaagcaaaaa
    33181 atataggaaa atatacaata tgttttataa tagtatgttt tttaatgatt actatgacct
    33241 taatattgag ttattttaat aaggataaac tatctgtaaa aactttaaaa ggcaatgtaa
    33301 aagatatagg gagagtaagt gtagtatata cacctaatat aagcaaattt tcttatgagg
    33361 aggtaattat aagtaaaaat ggagtaagaa ataatacaaa cccaaaatca agaattagaa
    33421 atgattattt aaatattgac aaaaaataca gtgactttgt taatgataaa ggaaaagaat
    33481 ttatatataa agatgatttg aatataggag aagcgtatac ctctgttaag tctgatttag
    33541 tacaaggaat gaatgcttta aatgattgta taaaggtttc aaataaaaat ttaaaaagtg
    33601 gggtagaaga aaattttgat attaatttaa ataagtctga ttttaaagaa aatagttgga
    33661 aaaccttgtt taacaaaata tataaaggta atttatatat ggtaattagt gaaactaata
    33721 tttcaggttc taaagtcaat aatatttgta tactaaagat agatataaaa aataagtctt
    33781 ataaattatt aaatagattt aatttaggat tacagaatgg agaacaacaa aatatcaatg
    33841 aaattaaatt ttctattgga agtaaattat acttagaaat agtaaataat aaaagtaaaa
    33901 atggatatat tgaaggacat gatagttact ctaactttat tatatatgat atagaagata
    33961 acacttttaa tataagtaat aaatttatgg ataatctaaa caaagaaaag aatgcaaatc
    34021 caaaggagat tggcttatta agtaaaacta agctagatta tatggtaaaa aataataaat
    34081 tgaatcttat agttacggat atgagtaatt ccataactaa tcttgtttat gatattaatt
    34141 ctaatgagat taaattagaa gattatgaga tacttgattt aaaagtagat tataatgaag
    34201 catcatctgg agttaggaaa gttaagctac tggatgataa gatatattct atttcaggta
    34261 ttaagaacag tatatcagga gaattaaaag gatttaaagg gattgttgat gtagtcggaa
    34321 ctaagccagt aaaatttcaa gtatttgata tgaaacttaa aaagaatatt tatgaagctg
    34381 agctaataaa tggagatata agtttacaag aaaagttatt ttttgttgca aattaagtgt
    34441 tagaattaat tttagaactt taaactttta tatgtatcac agataagtat aagtaaggga
    34501 gtgtctcaaa ataaactttt tagctcatga gacacttttt ttatatgaaa tcaaatatat
    34561 tttcattgtt tagatttatt ttgataatga aaaaaagatt atctttattt taagaaagac
    34621 atttatttat aattatatac aaaaatattt tttaatgttt ttgtgtataa ttataacaat
    34681 ttaatttata ttaatgcact taaatttgaa atagaatgct tatagtggta aaattaatta
    34741 ttagaatatt agaatattag aatattagaa tattagaata ttagaaataa taaataatac
    34801 attgtactta aaagggggag aaatttaaga tgaacaaaaa atatattaaa gcagggaatt
    34861 taattgatgg aaccggaaat agtattatgc aaaataaggg tataattatt gatggagata
    34921 ctatagttga aattgaagat ataagagatg atttaaatgg atatgatgtg tactattact
    34981 tagataaaac tgttatgcca ggcattatga attgtcatgt tcacttgaca atggagccag
    35041 ttggaaatcc aaagatatat tatgataatg tatcagatgt agagcttgta gtaaatacga
    35101 taaaacaact tgatgcttat ttggattcag gagtaacata tattagaagc ttaggttgtc
    35161 ccaaatatgt ggatgtacaa cttaaaaatc ttatagacaa agggtctata gatggtcctg
    35221 gtatagttac ttcaggtcca gttatatgta tgacaggagg gcatggatat tattttggta
    35281 ttgaaagtga tggagtagat gaatgtagaa aatcagccag aacagtttta aaaaatggag
    35341 tagattgtgt aaagataatg gcaactggag gtgtaacaac tgatggagtt gagccagggt
    35401 caccacaatt aactttggag gaaatgaagg ctgctgtaga tgaagctata aaagcaggta
    35461 aaataactgc cacacatgca caaggaagaa ctggtataaa aaatgcagtg cttgcaggaa
    35521 ttacttctat agaacatggt gtttatttag atgatgaaat aattgatttg atgcttgaaa
    35581 gaggaactta cttagttcca actgtggctg caccatattt tattctaaat gcaggaaaag
    35641 aaagtggaat aactgaagct actcttagaa agtgtgagat tgttgccatt ccacacaaag
    35701 agtcattcct aaaagcatat aaaaaaggaa ttaaaattgc agttggttct gatgcaggaa
    35761 cttcttataa tgaacatgga aaaacatatt atgaaatgaa actaatgtca gattatggta
    35821 tggataatat ggatataata gttgctgcta caaaaacagc atctgaactt ttaagaattg
    35881 ataaaaatta tggaactcta gaaaaaggaa agaaagcaga tgttatagtt gtaaatggaa
    35941 atccagtaga gaatatagac gtacttgcag atgtgttagc agtatttaaa cttggtaaaa
    36001 aagttagata aatagtataa aaataaaaaa gagtgtctaa agaaattttt aaataattat
    36061 agacactctt ttttattagt aataattaaa tcttttatac tttagaaaat agattctatt
    36121 ttatatttag atataactct ttaaaatcat tcttatgcaa tataatctat agaatctaca
    36181 catacaaagt atattcttga atcattagaa tttccaagta ctataacatc atttttctta
    36241 cctagaactt caacaccagt tagaaccaaa ctaccagcta ctacagtaac ttgattattt
    36301 atatttgaca tataaagatt atctaggata cctttattac aacagcaatc atcacaatcg
    36361 cagttgcaat tacattcttt gtaatgtttt ttatcaagat agtaacctaa agatgctatg
    36421 aaatcttcat aatctgcagg tgtaatatca aatgcaacag ctttaagatt acacaatgat
    36481 gctaaatcta cgtttgctaa tggagtagat gcagcaagta taaaatcaat tatagcagca
    36541 agtattgcat ctaatatagc cccaaggtct atcgtaggag gaataactgc atcaataagt
    36601 gcaattaatt cagctactcc tggtatagtt cctatagtat taattaatcc ctcaagagtt
    36661 aaagggactg gaataggata agatactcta ccagctatat ctattaaatc acagttacaa
    36721 gcagaaaatc tttcaaaagt accatcaagt ccagataaat tatcttttgg aggagctgaa
    36781 agatctatac ctaccaaatt agcacctact ataaagaaat ctgagataaa agcaaattga
    36841 ttaaagttta caaaaggtct tagagcatca tatcttagaa gttctaatgc ttctctcata
    36901 ctttttttac aacaacattg ttttatttta ggttctttat atttatttgg ataattatag
    36961 tatctatcag ctacttgata attttcatag tatctttcat ttgtatttgg ataatcttcc
    37021 tcatattctt gtgtaaatct aaagtcctct ctacatttat tattttccac taaatacact
    37081 ccttttatat tttaatttaa atgtatagat aattaagctt atctatatag taatattata
    37141 tttataatgt aaaaaaatgt tacaaaagat attataaacg aataaaaaat aataatttgt
    37201 cagataaact tgtaaatttt tatgaataat ccattctaaa acaaaaaact gtgtataaaa
    37261 aaggtttata tgttatattt atataaatat aacatatgaa cgagaaagga gtggtttgat
    37321 aaatgattga ggtagataaa ttgtgtaagt cttttacaag ggttgtaaaa gatgataaga
    37381 ataaaagttc aataagaaag ctaaagaaag taaaaactaa aaaagaagaa ttttttgctg
    37441 taaataatgt ttcatttaaa gttatggaag gtgaaattgt tggaatatta ggtccaaatg
    37501 gtgcaggaaa gactacatta cttagaatgt taggtggcat attaacacca acatcaggaa
    37561 gtataaatat ttctggatat gattattcaa tagatagaaa ttcagcaaaa aaagaaatag
    37621 gttatctctc tggaaataca aaactatatg gaaggctttc tccgagagaa cttctaacaa
    37681 cttttgcaag tctatatgag atgtcaaaag aagatataga agaatcaatt gaaaatattg
    37741 taaaaataat ggatatgagt gaatttatag ataatagaat tgaaaatcta tcaactggtc
    37801 agactcaaag aacatctata gctcgttgtt taatacattc tccaaaagta tatatttttg
    37861 atgagccaac actaggtctg gatgttttaa gtagtgcatc tattatagat tttatgaaga
    37921 atgaaaaact aaggggaaaa actgttcttt actcaactca ttatatggaa gaagcagaaa
    37981 ctttatgtga caagattttt atgattcaca atgggaaaat aattgcatca ggaacaccac
    38041 agagtttaaa agaggaatct ggagtaaata atttgagaga tgtattcata aaacttgcca
    38101 gaaaggagga catttaaatg agaagtaaga ttgtaaaata catatttaaa aaagaaatgt
    38161 tagacatatt gagagataaa aagactttat ttatgatgat tgttgtgcca cttcttttat
    38221 atcctttact tatgttatta atgattcaag taatgaatat gtctgcaagt agtatgaata
    38281 gtaaggacat taatatagct tttaataata aacctaataa ggttttagta tccatgattg
    38341 aagatgataa tttagaaaaa gatactaaaa atacttcaaa tgataaaggc aaaataagag
    38401 tgttagatgt agataactat aaaaagtcat tagaagaaaa taaaattgat gcttatataa
    38461 agatggaaga aaaaaaatca tctataaatt atcaaatata tataaattct tctcaagaaa
    38521 attcttctaa tgcactaaaa agaattgaaa ctgttttgga taaatataaa agatttacca
    38581 tagaaaaaac tttatctgaa aaaggattag atgtacaagc tactttagaa ccaataacat
    38641 atagcactgt agatgttgca aagacggaag aagtggcagg atacttttta ggtcagatac
    38701 ttccatttat attaataata ggagttttac taggttcaat atatccagca atagatgtta
    38761 tggctggaga aaaggaaaga ggtacattag aaacattatt tacactccca atatcaaact
    38821 tagaactggt tatgggaaaa tatatggcag tttctcttag tgcaatagta acagcaattt
    38881 taaacatttt atctatggga ctgactatgg catttatttt agttagtgga ggtattagta
    38941 gccaatttgg ctttggaaac tttaattatg gagacttagt cttaccaatt ataactactt
    39001 taatttgcat atgtcttttt tcaatggtag tttcagcaat aagtatgtgt gtatgttcat
    39061 tagcaaaaag ttttaaagat gctcaaaact acataacacc tcttatgtta attattatga
    39121 taccatcata tgtttctatg ataccaaata tagtattaga tagagtaaca gctgtaatac
    39181 ctgtagtaaa tatatcttta cttataaaaa gtgtattatc ttttaaaagc gatttaaatt
    39241 taatagcttt agttctggca tcaaatgtag cctttgttat attggcaatc atactactgt
    39301 ctaagatgtt caattctgag gaaatacttt ttggtaatag taagagtttc tctttcttag
    39361 agaaaagaag taatataaaa aaagggtcta taccaactgt aagtgatggt gttattttat
    39421 atgcagtagg attagttcta ttgatttatg ttggttcttt agttcaaatt aaatttggta
    39481 tggcaggtat tataatgaca caattcatga taatttcttt accgttatta tttgcatact
    39541 atattaaagc tgattttaaa gaggtattta gcttgaaagt tcctaaatta aagcatgtgt
    39601 ttgggagcat tgttctttgg attggtggat acatacttat tatgattata acacagctaa
    39661 ttttattctt atttcctcaa aatatggaag ttgctgaaag tttaaataag gctcttttta
    39721 tcaaagatag tgttttactg aatttactag caatagcttt attaccagct atatgcgaag
    39781 aaatgttttt taggggattt atattttctt catttagtaa atcaaaagat aaaaataagt
    39841 ctatcaagct agctataata tgcagtgggg tactatttgg tattatgcat atggatttta
    39901 ttagaataat tccaacatca atattaggta ttatatttgc atatagtgtg tataaatctg
    39961 gttcaatatt tgtatcaatg ttattgcatt ttttaaataa tagtgtagca gttgtgttaa
    40021 atcattatac aactggaaat ataaccaact tatataaatt tgttgaagtt gatttttcga
    40081 acttaaatgt gcttaaattt gccttaattc ttctaataag tcttatatta attatgttag
    40141 gattaagagt tttagataga aagtctttaa gaaattaagt ataaagttat tatatagatt
    40201 aaaatattaa taagcactaa agtatatgga tatatcttgt atataaaaat actttagtgc
    40261 tattttatat attttaatta tatgaattat ttatcgtttc atttatgtaa tgaaaatgtt
    40321 atataaatga aacaataaat aatttttatt ttagaaattt atatttaaat aatcaagttg
    40381 aaagtgagat actaaaaaaa ttaatttagg aattatttga tttattcatt tataaaaatt
    40441 aattactgat ctgtcgaaac cattgtaata agaaaaaaat gaaaaaataa agtgtgaata
    40501 tgttgcaaat actgtatttt aataaaaagt agtcatttct tgtaaaatgg atagtttata
    40561 tctactttaa ttttgtaaaa ttttctgcta ctataattat agaatgtagc atattcattg
    40621 tcttaactat tgatttatac atttcatata ggtataatag aaaataaatt ggattatttt
    40681 ggcatataat tatttattaa aaggtgatta tttttgttta aattgtctga aaaattttat
    40741 ttttatatta taattttaat attttctttt caaaactatc cattttacaa gaaatggaaa
    40801 cttttgagat gtacttattt gctaataaaa tagaggtgtt ttaatgggag gaaattttta
    40861 tgaggaattt acaaaaaaaa ttgatgtttt ttttatttat ttgtataatt ttacaaatta
    40921 catacacaac accagtctat tctttattca aactctataa aaacaactcc ataaataact
    40981 ttgagtctat tgtgtctaat aatcagctta ttagcaaaca tgcaatacaa ataatactta
    41041 ttatggctat aatatgtgta atacttatat tctatataat atatgataaa ttaaatttta
    41101 aaattaaatt gcaaaggata gcatatacag ataatcttac aggagcaaat actatagata
    41161 aatttgtaat tgatgctaac aaaatactat gtaaaaatac tcaagtaaag tatgctttat
    41221 tatatataga tattgataaa tttaaatata taaatgattt atttggatat gaagttggga
    41281 atgaaatttt gcgtaattta acaaagatta ttaagagtaa tatatttgaa gaggaaatgt
    41341 ttgcaagaat atctgcggat aattttatta taattatgaa atatatagaa gaagaagata
    41401 taacaaagag gttaaaaact atatttgaag aattagactt gtttaataat aatcaagaag
    41461 aaaaatataa gttagtttta agttgtggaa tctattttat acttccagaa gatagagata
    41521 tcaactcaat catagatagg gctaatatac ctcataaaat ggcaaaggga ggacataaaa
    41581 gttcatatgc attttatgat aataagattc atgaccaaga gataaaagaa aaagagatgg
    41641 aaaatacaat gttttcaagt ctagaaaata aagaatttat tatatactta caacctaaga
    41701 tagaacttaa tacaggagag atacaaggtt cagaagcact tgttaggtgg aaacgtcctg
    41761 ataaagggct aatacctcca aatgaattta tcccattttt tgaaagaaac ggttttgtta
    41821 taaatttaga tttatatgtg cttgaagaag tatgtatata ccttagaaaa tggattgatg
    41881 caggaataaa tccagttact gtttcagtta atgtttcaag gatacattta tattgcaata
    41941 attttataga aacatacaaa aatataattg ataaatacaa tatacctgca aagtatatag
    42001 aacttgaatt aacggagagt atcatatttg ataattttga tattttaatt gatataatga
    42061 ataatttaaa aaaaatagga tttttaatat ctatggatga ttttggttca gggtactcat
    42121 cattaaatat gttaaaagaa attcctatgg atatcttaaa acttgaccaa aaatttatta
    42181 tggaaactta taatagtaaa agaagcaaaa taattgttac taaagtaata gaaatggcaa
    42241 aagagttggg gatgaaagtc atatcagaag gagttgagac agaagaacag tttaaacttt
    42301 taaaagaagt aaagtgtgat atggcacaag gatatttgtt tggaaagcca atgccaattg
    42361 aagaatttga acatttaatt gtatctaact tggtaagagg gtaattaatc tgtaatataa
    42421 agaatttaat aaattgtgtt aaaaatggac tctaatgtag tgttcatttt ttttgtaaaa
    42481 ttttttatac ttttactaaa aagtaattga catgtacttt gtattattat attattgtat
    42541 taacaactta atacaatgat ataataagga ggcatgaaca tggaatggga acttgataat
    42601 aacaaaccta tatatataca attagtagaa catttaaagt taaaaataat ttcaggggaa
    42661 attaaaatag gatctaaatt agaaacagtg agagcactag cagaagatgc ggaagttaat
    42721 ccaaatacaa tgcaaaaggc tctaacagaa cttgaaagac aaggtttagt ttatagtcag
    42781 agaactaaag gaagatttgt aacagatgat aaggaaaaaa taaaagctat gaaagaggaa
    42841 atagctaatg tggagataaa tacattaaaa gtaaccttag aaaagcttgg atatgataga
    42901 gatgaaatgc taaaacttat tacagaaaat ctgaaaggag aattataaaa tggataaaaa
    42961 tataagcaat gtttctcaag atggaatagt tgaatttaaa ggtgtaaaca agagttatgg
    43021 aactaagaat gttttaaaaa atattgattt aaatatacca aagggaaaaa tagtcgggct
    43081 gttaggacct aatggaagtg gcaaaagtac aatgattaag ctaatgaatg gattattaca
    43141 gcctgataat ggtgaaatta tgataaatgg aatgaaacca tccatagata ctaaaaaaat
    43201 agtttcatat ttaccagaaa gaacttattt aaatgattgg atgaaggtat cagatttact
    43261 taagtttttc tatgattttt atagtgattt tgatgttaga agagcaaatg agatgattaa
    43321 aagcttagat attgatgtaa atgaaaagct aaagacaatg tctaaaggaa ctaaagaaaa
    43381 agttcaactt attttagtaa tgtcaagaaa tgcgagcata tatatattgg atgaacctat
    43441 aggtggtgtt gacccagctg caaggtcata tatacttaag actatattaa aaaattattc
    43501 tgaagatagt actttactga ttgctaccca tttaataagt gaaatagaaa acatatgtga
    43561 tgagataata ttcatatcaa aaggagaaat agtgttacaa ggagacgttg aagcaataag
    43621 agaagaaaaa ggaaaatcta tagatgcatt atttagggag gaatttaaat gttaggtaaa
    43681 ttattaaaat atgagttaaa agcaagtgga agaatattta taccgttata tatagccata
    43741 ttgatagtag ctgtatttaa cggaatattt atgaatacaa atatacttca ggtacaggga
    43801 ataggaatac tagtattaac aagtcttttt atggcattag gagttttaac tattgtagtt
    43861 acaattcaaa ggtttagaaa aaatcttttg ggggatgaag gttatttaat gtttactctt
    43921 cctgttagca ctagttcact tatattatct aaatgtataa cagcacttat atacgctgta
    43981 cttagtttta tagttgcagt attcactttt ggagttctta tgctttttgg tacttctgga
    44041 attttactac ctgaaatttt agatttgttt aacactagtt ttaaatggat ttctgaaaac
    44101 tttttagata ttttattatt agtagtagta atgtttattt catattcatc atttattttg
    44161 ttattatata catcaatctc aatgggacaa ttaccaaaat tcaataaaca tagaaacata
    44221 gtggcatttg cttcttttat agctataaat atagtaatat caattgttgg agatgcagtt
    44281 ggaagcattt taccaaatga agatacaaat atggtatatc atctttatca gagtcctagt
    44341 tttatgcttg caatacttgg tagtcttgta gttgcaatag cgttattttt cgctacaaaa
    44401 tttatattag ataaaaaatt aaatttagaa taaatgtttt tatatggagc catcttttga
    44461 gtaatgttaa aagatggctc ttattattta tgtagttaat tcatgtatat aatatgaata
    44521 gtgttttatt tctagttaaa tatatacata tgttgtataa tgatattgcg tgtaaaaatt
    44581 tgtaagaata actatacact ttatataagt tatatcaaga aaatttaaaa atatatggat
    44641 ttgagggaga agatatgaaa agttatacaa aggctaagtg gagtgtttgg ggtataatta
    44701 cattttcatt tgttttagta ttatttttaa ggatgtcaac tgctgttgtt tcagacaatt
    44761 tagcaaatga gttaggtttt aattctatac aaatttcaaa tatagcatcc ttttgcctat
    44821 atgcatatgc atttatgcaa atacctgcag gaattttgat tgataaatat ggagcaagaa
    44881 aaattagcag tcttggaata ataatggcaa gtttagggtc aattttattt ggtttgattc
    44941 aaagtataga attagcatat atttctcgtg taattgtagg ggcaggaaca tcagtaatat
    45001 tactttgtat tttaaaaatt caagggagat ggtttaataa gtcagaattt gcttctgcaa
    45061 cagctaaatt ttcatttgta ggaaatttag gtggagttct tgctactttt ccacttgtgt
    45121 ttttgtctga acttgttggt tggagaaatt catttttatt aatcggtata attggtgttg
    45181 taattggatg ttttatgtat attattgtta gagatacacc aaaagagtat ggattcaatg
    45241 tagatactga accctatgaa aagtcagaga aggttaatct tgttgatggt attaagtctg
    45301 ttataaagaa caaatcaaca tggtataatt caatgataat gttctctttt gttggtctta
    45361 caagtgcatt tataagcttg tggggagtaa gatacataat ggacgtttat ggtgtgagta
    45421 agagtttttc tgcgtttata gtatcatttt ttacatatgg atttatattt ggttcaataa
    45481 ttatggattt tgtatttgct aaaataaggt ctagcaaatt taatataata aaatttggag
    45541 caatgataga tttgtttata tggattgtaa ttgtagttgt ataccaggta aaaccaccaa
    45601 ttatagtttt accaatatca ttctttatta tgggatgtat agttatgtca catctacagg
    45661 tttttaatga tgccaagtat aaaaataaag aaatttattc tggactggca actagtgtta
    45721 ttaatacttt tgaatttata ggaagtggaa ttattaattt gattatagct atctctttac
    45781 aagtaaattc atataatata gttgatggat ataaaaaagg ttttgtagta tttatagtac
    45841 taagtattat aactatagta tcatctcata taggggtaaa aaatgatgat tttaaggcta
    45901 tatagtgttt tattaatagt ttaatttagt attatatttt gcatatatat aacaaatagt
    45961 ttgcattttc ctaatatgta taattggaat ataaatcttg tttactatgt acaaatggta
    46021 ttgtattata ttaaatagaa aataagaact ttaaactata atattggttc taaaatataa
    46081 ggtaaggagt tttttatgga tacgacgaaa atagatgata taagcaagtt agatttaaat
    46141 aatttagata ttaataagat ggatatggga ggtataatgg aaagtctatt agaatgggct
    46201 actacaagcg gagtaaaact tataataggc atacttatac tttctattgg atttaaaata
    46261 ataaaaaaat ttgtaaacca tgttatgtta ttacttagta aaagagatat tgatttaact
    46321 ttaagaaagt ttttaaagtc tcttcttttg agtgtactta aagttgccgt tataatcatt
    46381 gttctggaat attggggaat gagtttgtcc agttttgctg ctgtgatagc atcagcaggg
    46441 gtagcaatag gtttggcttt acaaggtagt ctatcaaatt ttgctggagg atttattata
    46501 ctattgatta gaccttttaa agtaggagat tacgtagaag cagcaggtca tggaggaacg
    46561 gttgaacaaa taggtctttt ttatacacaa ttggttactc cagataataa acagatactt
    46621 atacctaatg gttctgtatc aaatgatagt ctaataaact attcagcaaa gaatactaga
    46681 cgagttgatt tgacttttag tgtagggtat gaagatgata tactacatgt tagaagagta
    46741 cttaaagata ttgttaataa tcataaatta ataataaatg aaccagaacc atttatagga
    46801 gtagtagaac atggagataa tgctattaaa tttgcaacta gagtttggtg caagacagaa
    46861 gattattgga caatttatct tgatttacta gaagaggtta aagttaggtt tgacgaagaa
    46921 ggaattacga ttccatatcc taaaatggat ttaacggtaa aagaattaaa caaaatttaa
    46981 ttttttaata tagtgtttaa atttaagaat atcatataga tatacttata aggtttgtaa
    47041 aaaattaata agtactgtta ttttgtaagt aaaaatataa aaaaatggga gtgtctcaaa
    47101 atgaactttt tagttcatga ggcactcttt ttgtacgaaa taaaatatat ttttattatt
    47161 tcaacaatga aaaagaggct tgtttccatt ttgagacagt ataattttta tgtaacttta
    47221 attttagtaa atataaagtt ttaaaattga taaaatagga ggaattttta atataaaagg
    47281 gtaaataaag ggtttagagg gcataatata gaataaatta atatatttaa ggagggtttt
    47341 tatgtgtaaa aaaacgtatt tattagtggt aagtatgctt atagcgggtt tattaactgc
    47401 atgtagtggg agtccaacta aggattcagg acaagcacaa gataatacaa aaaaggaggc
    47461 aaatgcatca aataacgctt taaaagatga aaaaaataat gaaaatttaa tggaacaaga
    47521 ttttaaagtg ccatacacag atgcaataaa catatttaaa gataaatata aggatgctga
    47581 tatagtagat ttaagtcttg agagagattt aaataaattt gtttatactg tggaaggtgt
    47641 agatgataat aatgaatata agatgaaaat tgatgctaat acaaaagatg tattagaaga
    47701 taaaacagaa aagttggatt cagaagattt aaatggagtt gctagaaaag aaaaattaga
    47761 tttaaatgac ataattaaac ctcaacaagc tatggaaatt gcattaaaag aacaaaatgg
    47821 aatggttaaa gaatggagtt tagacaaaga tttagatgtt actttttata aaataagaat
    47881 agataaagat aaaaatgaat atgacataaa agtagattct aaaaagggaa ctgtattgaa
    47941 ggtagaaaaa gaagattaga agatttaaac tatctttaaa ataatttctt ttttgaataa
    48001 attttgttta aaatataaca agcagggtat aaagagacta aataactatt ttaggaggag
    48061 tacggtatgt cattgaaatc actaaaaata aaagaaaatt tatattgggt aggttcactt
    48121 gaccctgatt taagagtatt tgacataatt atgtatacac cttatgggac tacttataat
    48181 tcatatgtat taaaaggaac agaaaaaaca gttttatttg agacagttaa agataagcat
    48241 tttgacaatt atattgaaag attaaatgat ttaaatatag attttgaaaa aatagactat
    48301 attgttgtaa gtcatactga accagaccat gcaggaagcg ttgaaaagct tttggattta
    48361 gctaaaaatg caaaagtagt agcttcagaa acagcaatta aatatcttaa ggaaatcgta
    48421 aacaaagact ttgaatatgt tgcagttaca gatggagata cattatcaat tggggacaaa
    48481 actttagaat ttttctctgt acctatgctt cattggccag ataccatata cacatatata
    48541 aaagaggata aaactcttgt aacatgtgat tcatttggta gtcactatag taatgataag
    48601 atagtaaata cacttgatga aaatgaagaa aaggattact tggatgcttt aagatactat
    48661 tatgattgta taatgggtcc atttaaacca tctatggtaa ctgctataga aaagataaaa
    48721 gatttagata tagatactgt atgtccaggt catggtccag tattaactga aaatcctaga
    48781 aaaattatag acctttatta caactggagt gtaaatgaac aaataaagtt agaaaaagaa
    48841 gttacaattt gttatgtttc tgcacatgga tatacaaaga ttatggcaga agctataaaa
    48901 gcatatattg aaaaaaatag caactataaa gtaaatttat ttgatgtaat agagcataag
    48961 caagaagata ttttggcaaa aatagcagta tcacaaggtg tattatttgg aacaccaaca
    49021 atattaggag atgcgttaaa gcctatatgg gatatattaa tatcgttaaa cccagttctt
    49081 catggtggaa aagttgcttc agtatttggt tcatatggat ggagtggaga aggtatagaa
    49141 aatgctatgg agagaataag tcagcttaga atgacagcag taaaaccttt tgctgttaac
    49201 tttaaaccat caaatgaaga gattgataaa ttacattctt atacaggtaa attcctagat
    49261 aagttaaatt ctacttttgg aagtaaaaag aaaactaaga aatttaaatg tgtaatttgt
    49321 aatgaagttt ttgaaggtga tagtgctcct agtgtatgcc ctgtatgtgg agctaaggaa
    49381 gaccaattta tagaagttga agaagatgaa gttactttta gaaaagatac tgatgaatat
    49441 ttcgtaatag taggaaatgg agcagctggt ttttatgcag cagatgctat aagaaaaaga
    49501 aataaaactt gtaagataac tatgatttct aatgaagatg agttgactta ctatagacct
    49561 gcactttctg atggtataaa tgaagaactt ggttcagatt tctacatgga agataaagat
    49621 tggtatgata aaaataatat agtagtaata ttaggaacga atgtagataa attagatgaa
    49681 gtgaataaaa ctattatagt gaatgatgga gctattaaat ttgataagct tgtaatagct
    49741 acaggaagta gaaactttat accaccaatt aagggccatg atttagaaaa tgtgtttact
    49801 cttagaaata taaaagattt atatagtgta aaagaagcac tagaaaaatc taagaaagtt
    49861 gtagtgattg gtggcggttt attgggactt gaagctgcat gggaatttag actaaaagga
    49921 ttagaagtag tagtagttga agccatggat agcatactat caaaacaact tgataaagaa
    49981 ggtagtaaaa tattagaaca atgtgtaaga gatacaggaa tagatgtaag attgggtgta
    50041 gcagttgatg gtattgaagg tgatggaaaa gctcaaaaag ttgtatttaa agatggagat
    50101 agtgtcgact gtgatatggt agtattttca attggtgtaa gagcaaacac tcaaatggtt
    50161 caggatacat ctgtaaaaat tgacagaggt attgttgtag ataagacatt acagacaaat
    50221 attaaagata tatatgcttg tggagatgtt gcacaagtgg gaaatattag tttagcaata
    50281 tggccatctt cagtagaaat gggaaaaata gcaggggcaa atgcaagtgg agataatttg
    50341 acatttgaaa gtgaagtata tccagtttca ttagatgcaa tgaatgtaaa agtatttagt
    50401 attggtaata tacaaaattt tgataaagaa atttcatcaa aagatgaagg tcaaagaata
    50461 tataaaaaat tatttatgaa agatggttca ttagttggag ctatacttat aaatgattta
    50521 agctgtactg ttaaattgat aagattaata tctgaaaaag gtgattttga ggatattatg
    50581 aaggctgata tactataatt taaatacatt aaaataaaaa ggagttgtct caaaattgat
    50641 ttttttctaa tcaaatttta aattcaactc cttttttgaa tttttatata aaataacatg
    50701 gaaattttag taatgtctgt ggttacatac ataggtttaa ttgtttttta tatggattgt
    50761 ctctggtata ataaattgaa ttgtgtttga ctgatagata tttttattga aagttaatac
    50821 ctgttatgcg ataataagga cgtgttaggg gagtttttat aataacaatt aatctcagtt
    50881 tttgtgttcc aatggtagca tcaacacatt ctgatgtagt agttcttttc ttataaaaat
    50941 tagttacaaa tatgcttgta attatttgat atgtaaattt accaatatta taaatgatga
    51001 cctcgataat aaggagagtg aaaaataatc tatgaacgaa aatattttga ttgtggatga
    51061 tgaaaaagaa atagcagatt taattgaagt atatttaaaa aatgaaggtt ttacagtata
    51121 caagttttat acaggtaagg aagctctaga atgtattgaa tctaaaaatt tggatatggc
    51181 tattttagat attatgcttc ctgatattga tggatttcat atttgccaga aaattcgaga
    51241 aaaatactat tatcctatca ttatgttaac agctaaaatt gaagatatag acaagataat
    51301 gggtttaacc ataggtgctg atgattatat aacaaagcca tttaaccctt tggaagttgt
    51361 tgcaagagta aagacacaat taagaagata tatgcgatat aataattctt atgaacaaca
    51421 gtcgataatt gttaatgagt atgatattaa aggattgatt atcaataaag aaacacataa
    51481 atgtagttta tttgggaaag aagtagcatt aacaccgatt gaattttcta ttctttggta
    51541 tttatgtgaa catcaaggaa aagtggttcc ttctgaagaa ttgtttgaag ctgtatgggg
    51601 agaaaaatat cttgataata ataacacagt tatggctcat atagggcgat tacgtgaaaa
    51661 aattcatgaa ccttctaaaa acccgaaatt tataaaaact gtatggggag taggttatac
    51721 aattgaaaag taaaaatatt aaagtcaatc ctgactttac tcaagtgaga aataaaattt
    51781 ttatgagaac agctttaatg gcatttatag ccattatttt catatggatt ttatattctt
    51841 ttatattgta tggtaagttt tctatctgga tagtatcatt ctttgaaaat gcttttcgta
    51901 tggaatataa agctgcattg aatttatatc agcagatttt ccgtaatagc atggagctct
    51961 tcatgatact agctatggtg attgtgtttt ttataatatt ccgtgtttat ttaaattggt
    52021 ttacaaaata ttttagtgaa ataaatcaag gtattgactc tcttatcaaa gaagatgttg
    52081 gagaagtggc tttatctcca gagttattgg caatagaaaa gaaaataaac tcaattaaac
    52141 atatacttga acaacgtaaa tttgagacac aaatggcaga acaacgtaag aatgaactta
    52201 ttgtttatct tgcacatgat ttaaaaacac cacttacatc agttataggg tatctgacac
    52261 tacttcgaga tgaaagtcag atttctgaag aactgcgaaa aaaatattta tctatttcgt
    52321 tggataaggc agagcgtctt gaagatttaa ttaatgaatt ctttgaaatt acaaggttta
    52381 atttatcaaa tatatcactt gaatacagta cagtaagctt aactcgtatg cttgaacaac
    52441 taacatatga gtttaaacct actttgatga gtaagaattt aaaatataca ctgaatgtta
    52501 caccaaatat gatgataagg tgtgatgtta ataaaatgca acgtgtattt gataacttat
    52561 tacgaaatgc tgtttattat agttttgaag atactactat tgaaataaca gctgtacagg
    52621 aggatgatta tataaagctt aaatttataa attatagcaa tacgattcca gaggaaaaac
    52681 ttgagcgtat ttttgaacaa ttttacaggt tggatacatc tcgtaattca aacagtggta
    52741 gagctgggtt gggacttgct atagctaaag aaatagtgga gcttcataac gggacaataa
    52801 cagctcatag cgagaacaat ataattacct ttaaggttat tattccgatt gtaggaaatt
    52861 tgtaagaatt taagtataaa aaaataggaa attctttagg ataaataaat aaagagcact
    52921 cttgttattg atataattac tgtatcaaaa caagagtgct tttattttga tacagtaatt
    52981 atatcaatag aaaaatgtga aaatatatta tgtggaacag atgcaattgt aagtgaaggt
    53041 tgattggatt tgaaatagaa aaagtatttt aacatgtttc tgtagattgt ataaaaataa
    53101 ataaatcaac aaaggagaat caaagatgaa taataaaaaa attgcagtta tatttggtgg
    53161 aaactcaaca gaatatgatg tatcattaca atcagctttt gcagtacttg agaatttgaa
    53221 tacggaaaaa tatgatatta taccaattgg aattacaagg gagggtaatt ggtatcatta
    53281 tattggagat tataataata tccagaataa cacttggttt gaaagggata ctgatataat
    53341 tccagttatt gtttcgcaga accgtgtcaa aaatggtatt attgaatttt taattcctga
    53401 tgctgtttct cagaatcata ttccaaatag tgctattgaa tcatgtgaaa atgatattaa
    53461 atacactaaa cttgattttg tatttcctgt attgcatgga aaaaatggag aagatggaac
    53521 agtgcagggg ttatttgaat tggcaggtat acaggttatt ggatgtggta ctctttcttc
    53581 agcattatgt atggacaaag acaaatcaca taaacttgtt cattcagaag gtattaaagt
    53641 accaaaatca atattactaa aatactcaga taaatttaat gtggctgaac tgtcaaaaga
    53701 cttaacttat ccattattta taaaacctgt gcgtgcaggt tcatcatttg gtattagtaa
    53761 aatttataaa aaagaagagt tacaagtagc agtagacttg gcttttgaac atgataatga
    53821 agtaataatt gaggaaaata ttgatggttt tgaggtaggg tgtgcagttt taggaaacaa
    53881 tgacttactt gttggaagag tagatgaaat agaattgtca aaaggatttt ttgattatac
    53941 agaaaaatat acattgaaaa gttcaaaaat tcatatgcca gctagaattg atttggattg
    54001 tgagaaaaga atacaagaga cagcaaaaat tatttataga actcttgggt gttctggatt
    54061 tgctagagta gatatgtttt taactccatc tggtgaaatt atttttaatg aagtcaatac
    54121 aattcctggc tttacttctc atagtcgtta tccaaatatg atgaaaggta ttggattgtc
    54181 ttttgaagaa atattggaca agataattga ggtgtacata aaatgatgaa taatatttta
    54241 ttagataaaa ataaagaaga taaaatgaca aatactatct tattgactaa agataaagtt
    54301 tatgatggga atctaattct agtaaatgct tttttaccag ttaaaacatc tgaagatata
    54361 gatttaattc ctgtagatac aaggtttcca agtattctta tgaaacgtga agctacaaac
    54421 attttacaaa atattttaaa aagtatatgt ggaataaatg aaatagtacc tgtaagtgga
    54481 tatcgtactg cagaggaaca acaagatata tattcaagtt ctctgcgtga caatggaaaa
    54541 gactttacta aaaagtttgt agcacttcca aatcacagtg aacatcagac agggcttgct
    54601 attgatttag ggttaaagaa agaagttata gattttatct gccctgaatt tccttataat
    54661 ggtatttgta atgagtttcg taaggcagca ctacattatg gttttataga gcgttatcag
    54721 tgtaaaaaag aagaaataac aggaatatct caagaaccat ggcattttcg ttatgtggga
    54781 tatccgcatt ctgagattat caataaaatg aatctcgctc ttgaagaata tatagaatat
    54841 attaagagat tttcgtatac aaattgttta aaaatagaag ataaagaaaa aattatagaa
    54901 atcttttatg tgcctatcca tactaaagaa gaagtgagaa tctctatacc tgaacaatgt
    54961 gtatatcaaa tatcgggtaa caataaggat ggttttattg tgacattttg gagaaataga
    55021 aaggactaag aaatggagga acaagaatga ttaggaataa atcttatgca gggcttgatt
    55081 attttaggat tatagctgca ttacttataa ttgcaattca tacatctcca ttattatcat
    55141 atagtaaaat ggctgacttt gtgttaacta gtataattgc tcgtattgct gtgccattct
    55201 tttttatgct atcaggcttt tttctaattt caacatataa ttataattgt aataaactga
    55261 aatcttttct aaaaaatgta ttatttattt acgggatagc tattgtaatt tatattccct
    55321 taaatattta cactggatat ttttccatga ataatttagt gcccaatatt attaaggaca
    55381 ttgtatttga tgggacttta tatcatttat ggtatcttcc tgcatcaatt attggtgcaa
    55441 gtattgcata ctttcttgta aaaaaactag gtttaaagta ctcactagta atcactattg
    55501 ttatttatgt aattggtatg tttggtgata gttattatgg ttttttagaa aaaataccac
    55561 tattaaagaa tttatatggg tatatttttg aagtatcaga ttatacacga aatggtatat
    55621 tttttgcacc tgtatttttc atacttggtg gaataatatc taataaatct aattatatgt
    55681 caactaaaaa tagcttgatt ggatttctta tatcattctt acttatgtta tgtgagggaa
    55741 tgtttttaca taaactaggg gtacagcgtc atgatagcat gtatattatg ttattgccat
    55801 gtatgtattt cttatttaca gccttaacat ttttgaaagg ttctcgagct aggttattgc
    55861 gaacatcatc attaattatt tatattatac atcctatgat gattgttgtt attcgtatgt
    55921 tttctaaaat attcggaata caaactgtct tggttgacaa tagccttatt cattatatag
    55981 tggtaagtat agcatctttt atagcttcta taattattat attgattctt aaacctctaa
    56041 aaaaatactt gaaaggagaa cataaggtaa ataccaatag agcttggatt gaaattgatt
    56101 taaataattt ggaacataat gtaaagatga tacaaaaagc tatgccagaa gattgtgaat
    56161 tgatggcagt tgtaaaagct aatgcctatg gtcatagtgc ttttgaagta gcgacttgtg
    56221 caaaccaaat aggtgtaaaa gcatttgcag tagcaacaat agatgagggg attgatttac
    56281 gtcgatatgg aatactagga gaaatattga ttcttggata tactaaccca ataagggcaa
    56341 aggaacttca taaatacaat cttacacaga gtgttattga ccttaatcat gctatctctt
    56401 taaacaaaca gaaatacaac ataaaatcac acattaaaat tgatacaggt atgcacagac
    56461 tgggttttga tgttaatgat gtgaggtcaa ttttaaaggc atttaaatta aaatacttag
    56521 atatatgtgg catatttaca cacttgtgtg tttcagatag tctgaaagat gaagatgtag
    56581 actttacaaa taaacaaatt gaatgttttt ataagttaat tgattttctg ttaaaaaaag
    56641 gtataaaaat tcataaagta catattcaaa gtagttatgg tttttttaat tatcccaatc
    56701 ttaagtgtaa ttatgtaaga attggaattg cattatacgg gatattaagt tctccaaatg
    56761 atacgactaa attgcaactt gatttacgac ctgttttatc cttaaaatca caagtaattc
    56821 ttattagaaa aatacaaaaa gatgatagtt ttggatatgg aagagtcttt attgcaagca
    56881 gagatagcgt aattgctata ttatctattg gctatgccga tggtatacct agaaatttat
    56941 cctgtggaaa aagttacgta ataataaatg attgtagagc agcaatagtg ggtcgaattt
    57001 gcatggacca acttgctgtt gatattacag atatacctaa tgtagaagtt ggtaatacgg
    57061 caataataat aggaagagat aatttagctg aattatctgc ttctgaagtt gcaaataact
    57121 catgtagtat atcaaatgaa ttattgagca gagtaggaag aaggttaaat gttataaaga
    57181 agtaactcaa ttaaatagta atatttgttg tactgtgtaa tttattttac tctgactaga
    57241 catttttagt aatattatgt ctaatatata ttttttataa cttacatgac aatttaagtt
    57301 ataaaaaggt gatgtttcag atttttattt tgaaacatca ccttttttgt tataatatat
    57361 aataaaataa ttatacctta actgtaaact tatatagatt atttactttt taatattaga
    57421 ttcatttttt gagattggta tataataaac atatagagta tataataata gttaaagtta
    57481 aaaaagggga aaagcaatat gcagtatata caagaactac ttgatttgac tcaaaattat
    57541 tgggtgttag ccacaataat cggcttatta agtgcattta tagaaagctt tataccagcc
    57601 ttaccacttg ttgctatagt tacagcaaat gctgcaatac aaggattatt tattggatgt
    57661 ttgttatcat ggattggctc aggacttggg acaacttcat tattcttatt aataagcaga
    57721 tttaatgata gtaagctttt taataagttg agaaatagta aaactgaaaa agcaataagt
    57781 tggatggata aacagggatt taagttatta tttatagcgt atgcctgtcc atttatgcct
    57841 ggttgtttag ttactatcgc atcagctttt ggtaaaaaag atttaaaaga ttttgtgcca
    57901 gcaatgttgg caggaaaatt tgtaatgttt atagttataa gttacgtggc aagtgatata
    57961 gaaggtttta taacaagtcc tttaaagata gcatcattta tattattggt gtttttgtca
    58021 tggaagattg gaaatagagt aaataaaaat cttgaaaatc ataattatga tttccatcat
    58081 aaaaaacatc acaatgataa agatgataaa atgatttagc ttgtacgaaa taaaacgtat
    58141 cttaaaatga tttagtacta aattatttta agatacgttt tattttttgt attaaggtac
    58201 aaaattttta gttcttttgt aaactaaaat atataaaact tatttatact tagttcaaaa
    58261 tattgttatt tattttttct acaactataa taaaatataa aattgatatc caatcaaaaa
    58321 aataactatg aaatttaata gcttagatat gaatttttct gtttttgagt tagtttttat
    58381 aggtagtaaa gaaatgttta tggtaatggg ataaaacaat tcaatacctt ctttagtaat
    58441 aaggtcaaga cacaagtgag atagatatcc tattataaac ccactggaca aacatgagaa
    58501 aactatatta ttgttagtga agattgtcag agatttaaaa aaactataaa taagtaataa
    58561 ggcaattaga ctgtgagtaa accctctatg tctaaaccta cttccaaata atttgtatat
    58621 taacataaat tttttactta tgtaagaacc tctcatatct atatctggaa ataaagaacc
    58681 taaatatgca aaataaatat aaattataat taatactatt ttatatgcaa tatcgtattt
    58741 aactaggtac agattgttta taaaggggag tatcaaaagt gcgaatatat aacctcccct
    58801 ttcatgtgtt tcttttatca tataaaaatc ctcctgaatc gtcactataa acattatatt
    58861 ggtaaattta gactatcttt tattatatta tatagcaaac ataagttttt ttcaaaagga
    58921 ttttaatatt taattaatct tgagatttta aatttttgta attttctaaa gcaccattcc
    58981 aatttactac attaaaccag ttgtcaatgt attcatttct tctattttga tattttaaat
    59041 agtaagcatg ctcccaaaca tcaagtccta ttataggagt taggttttta cttacagggc
    59101 tatcctgatt tggagtagtc ataatagata atttgccatc tttagtagct acaagccaag
    59161 cccaaccaga accaaagaca tctaaagcag atttttggaa ctcttgctta aatttttcaa
    59221 aagaaccaaa gtctctatca atagcttctt ttaaagattc agaaggtatg gttttttctg
    59281 gcgtcattat atcaaaaaag aatttatgat tataagctcc acctgcatta tttcttacag
    59341 ttgtagcaat atctttaggt aaagaatcta aattttgcaa taattcacat aaagaataat
    59401 tataaagctc aggatatttt tcaagagcag catttaattt atcaacataa gcttgataat
    59461 gcttatcatg atgcagtttc attgtttctt tatctatata aggttcaagt gcatcatatg
    59521 cataaggtaa tggtttaacc ttaaatttgt tattttcagg tgtaaaagca aatgaagtta
    59581 tgcactgtga gattataaat aaagacataa taactggtat taatattttt ttcttcataa
    59641 aaatcacctc ctaatatagt atttctagaa ataaaaaaaa tatgaaatat taacagataa
    59701 tttataagaa tttaatagca atttcatttt aaattgaata agttttaaag ccaaagacaa
    59761 aactatgaaa tatagaataa gactaaagga cagaaaggaa ttttgattat atggacggca
    59821 atatttcaat ttattataaa ggtgatatat ctaaaaaaga agatattaaa tttaaaataa
    59881 aagaatctgt aaataataca agactttcta gtagaataga gtataaggat gaggaaaaaa
    59941 cttttgattt tgaaagattt aatgtaattg atgctattta tggaaataaa ccatttgaaa
    60001 aagatggaaa agttattgtt tttaatggaa atatatataa ctatcatgaa ataaaagaag
    60061 aattaattaa aaaaggacac aattttacta caaatgatga tattgaagtc ttattagcat
    60121 cttatataga atttggtaag aattgtgtac ataagattaa aggaatgttc aactttataa
    60181 tctatgatag agaaaatgaa agtatatttg gagcaagaga tttatttggg ataaaaccac
    60241 tttattatat aaataaggaa aatgcaataa ttttttcctc agagtataag tttttacttg
    60301 aatatatgaa aaatttaaat ataaatgaaa gaagcttaca aagttatttt tcatttcaat
    60361 atgtacttcc tgaagatact atgatacaag gaataaggct gataccagca ggtcactatt
    60421 ttagggtaga aaatggtata ctatctttaa agagatataa taaacttgag tttagaagta
    60481 gtacaaaatt tttttatact aaaaatcact taggcaatag agatgtgaat gaggatgata
    60541 taagaaatat agtagtagat tcaatagtaa ctcatatgga agaggagaaa gaaattggaa
    60601 catttttgtc tggtggaata gattcatcta ttataactac tgtggcttca caaattaatc
    60661 caaatataaa atctttttct gcaggcttta gtgtcaaagg atatagtgaa ttagaagtag
    60721 caaagaaaac agctgataag ttaggtatag aaaatatcca gattaatata acacaagatg
    60781 aatatataaa atcattaccg aatgtaattt attctttgga tgaccctata gcagaccctt
    60841 cagaagtagg tctttatttc ttaattaaag aggcaggtaa acatgttaaa gtagcattgt
    60901 ctggagaagg agcagatgaa ttatttggag gatataatat atataaagag tatagtacta
    60961 tgaaatcagt tgtcaattca cctacttata ttaaaagtat attaggaaga gtttcagaac
    61021 ttatgccaaa cataaaagga agaaattatc tttatagagc tacaacacca ttagaaaaaa
    61081 gatatatagg aaatgcaaaa gtttttgaaa acagcgaagt aaaaagattc ttttttaagt
    61141 ataaggaaaa gaatatatat gaatacctgt tgtctaattt gtatagagat gcacaaaaaa
    61201 ataattacga ttatataagt aaaatgcaac atatagatgt gaatacatgg cttcaaggcg
    61261 atatacttca aaaaattagc aaactttcta cagctgagca ggttgaactt agagtaccat
    61321 ttttatataa agatgtattt gatgtcgcaa aaaatttaag aatggagcaa aaaataaata
    61381 agaataatac aaaagtttta cttagagagg cgtttagaga aatagtccca gaacatgttg
    61441 ttcaaaggaa aaaattagga tttccaactc caataagagt ttggttaaaa gattctctag
    61501 gggatattgt aaaggaaact atttataatt caaatgtaga tgaatttata gataaaaaat
    61561 atgcaataaa acttttagat acgcatctta aaggtcatag agataattcg agaaaaatat
    61621 ggactatatt tacattttgt ctatggcatc aattatttat tgagcataaa aatgtcgagt
    61681 attaatactt ttttcaatat taatcagagg gcaaaagcat gcaatgtttt caccctcttg
    61741 attattatgg aataggataa gtagaatttt gattgattag tttactatct caataaaatt
    61801 attggcaaat attttgacaa gactactttc aacagctaaa tttaagtttt gtccatcatc
    61861 atatccagcg gaaatcaatc ctagtaagtt tccaaacata tctaaaagag ctcctcctga
    61921 actaccacta gagattggag ctgtaaattg tatcatttga accgtttcaa aatcacgaaa
    61981 agctgaaata attccatctg aaactgtatt aaaaagacct agagggcttc caattgcaac
    62041 tattttttga cctctcacag gttttttact gactttaaca ggtattggct tgcattttct
    62101 atcaaccttt atcacagcta aatcataatc tgaatggtat tttataattt ggtaagatgt
    62161 ataaacttta tcatcatttt caaatctaac taaaaatgaa tacccatcat tgactacatg
    62221 aagattcgta agtatataac cttcattatt tattactact ccagaaccgc tcttaaacgg
    62281 tttattttcg ttattgcaca caataatcat aacaacagaa gctgataact ttgcaaggtc
    62341 ttcataagaa agttctactt cctcatcttg tacaattttt ttagatgtta gatttgtgtt
    62401 attaagtgta tttttagagt taggtttatt cgtagtagga gaagtcttat tggtattttc
    62461 actgtaattt atatttgtaa tatgcctttc aaaaggtatt tctaatatat ttggagtctt
    62521 cctagaaagt tcaaatagag tagaaaattt tgaacattca ggatataaat caagaatatc
    62581 tttatttgga tttatatata aaatatcaca cccaagttgt gataaaaaat ataagaaaaa
    62641 aagttcttgc cttttaatat ttccaaagta tactatcttt ggtgaaatag tagtcttcac
    62701 cttgttataa aataatttag gtagaaaata gtccatccaa cacaaaagtt taactgcaaa
    62761 gtttttgatg atagaggatg tacaatttgg catacttgtg gaaaataaat ctaaagtatt
    62821 tttaaatgca atctttttag tccaatttaa ggtgtcattt tctattttac atggaaagtc
    62881 gatattatat aaatcccaac tgttaaactt agaactatta taaatattaa aaattttaag
    62941 catcttatct gtttgttctt tgtcaaaatt tatttttaga ttgtttaatc taatataggg
    63001 aattgtagga ttattaaaaa aataagtatc tatattttta attttttcta tgtatttatc
    63061 aattgaatca tcaacaccta tatatcttgt aaagtagact tctttaatat atgaagaacg
    63121 cttattttta taggtagtat cagatataaa ttcaattaga ggttcagtag acttttttat
    63181 tgaaatcttt aatggtttaa tagtacaaat catatttttt ctcctataat aagatgatat
    63241 aatctattat aaaacaactt aaaacaatat agtacaataa ttttgtagtt tcaaaataaa
    63301 atatgtactt gtttatataa atgatatata attacatatt aaacatagct tttatgcatt
    63361 taataaagta tgtaaaatct atgtaaaaag taagaaatat aaacattttt ttaattatat
    63421 tttaaaaata tcaagcaagt tttattcaca aatgaataaa aaatgttata atatgattaa
    63481 agaaaaagat aaataattag caagatttgt ttagctaaaa ttaacaaggg agcgataaat
    63541 tatgggtata acattatcaa aaggccaaaa ggttgattta actaaaggaa atccaggtct
    63601 taaaaatatt ttagtaggtt taggatggga tactaacaag tatgatggtg gatttgactt
    63661 tgatttagat acagcagcat ttttaacagg agcaagtgga agtgttacta atgatggaga
    63721 ttttgtattt tacaacaatt taaaacatac atctggagca gttgagcatc taggagataa
    63781 cagaactggc gaaggtgatg gagatgatga acaaatagtt gttgatttat ctaagattcc
    63841 tggagaaata agcaagattt cttttactgt tacaattcat gatgcgacag aaagaagaca
    63901 aaattttgga caagtaagta attcttatat aagaatagta gataaagaca caaatgaaga
    63961 gttaataaag tatgaattag gagaagattt tagtatagaa acagctatag tagtagctga
    64021 aatatataag cacaatggag aatggaagtt taatgcacta ggttctggct ttgaaggtgg
    64081 tcttgctgca ttatgtggaa actttggaat aaacttataa tttcaactat aacaataaac
    64141 taaaggggga tattttccat ggctatagta ttaaaaaaag gacaaaaaat cgatttaact
    64201 aagggaaatc caggtcttaa aaatataaaa cttggactag gatgggatac aaattcattt
    64261 gatagtggct atgattatga tttagatgta agtgttttca tggttggaga atctcaaaga
    64321 gttgaaaaag atgaagattt tatattctac aataacttaa aacatccatc tggagcagtt
    64381 gaacacttag gtgataatag aactggtgaa ggtgatggag atgatgagga aatattagtg
    64441 aatttagaga caatgccaaa gcatatacaa aagatagctg taacagttac aatatatgag
    64501 gctgctgaaa gaagacaaaa ttttggacaa gtaagcaact catatataag agtattaaat
    64561 tctgaaaatg atgaagaaat attaagatat gacttaggtg aagaatttag tatagaaact
    64621 gcaattacag tatgtgagat atataagtat aatggagaat ggaagtttag tgcagttgga
    64681 gcaggatttg aaggtggctt agaagcactt tgtagaaact atggcttaaa tgtttaattt
    64741 aagcaatata atatattaaa tataaataac ctatacaaat aatgtatagg ttatattata
    64801 taaaattttg tggaggttta gtatgtcgat taatttatca aaaggtgata aaatagattt
    64861 aaaaaaatct aacccaggat tgagtaacat acttgtaggt ctaggatggg accctgtgca
    64921 acaatctggc ggaggttttt ttaaatcgtt atttggtgga ggacaagctg atatagattg
    64981 tgatgcatct gtatttatgc ttaatcaaga aggtaaatta agtggaataa aagatttaat
    65041 ttattttgga aatctaaaaa gtgcctgtaa atcagttttg catacaggag acaatctaac
    65101 tggtgagggt acaggtgatg atgaacaaat cctagttaat ttggataaag ttccatcaaa
    65161 tattcataaa ttattgtttg tagtaaatat atacaattgt gtagatagaa aacaacactt
    65221 tggaatgata gaaaatgcct atataagagt tgaagaccaa ggtaataaga aagagatagc
    65281 aaaatacaat ctatctgata attattctga aaaaactact cttatagtag gagctatata
    65341 tagaaaagat ggaagttggc aatttaaagc aattggtgaa ggaacaaaag atgcgggtct
    65401 taaagaagta atgcaaaatt tagacaggat tgagtgtgca tatggaattt aataatgata
    65461 tcaaatatta taatgtagat aaagaagaag ttacaaaaga cttatctgtt aatcctgaaa
    65521 aaggtttatc agaatcagaa gtcaagacta gaagagaaaa atatggtttg aatgaattta
    65581 ctccaaaaga agagggtagt ttttgggatg atttaaagga aagtttaagt gaaccaatga
    65641 tagttatctt gattattgca gcagtagtaa gtgcagtaat tggggaaact catgatgcaa
    65701 tagggattgt aggtgctata gcaataggta tagcaatagg tatgattaca gaaggtcgtt
    65761 ctaagaaagc agcagaggct ctttctaagt tgactgaaaa catagaagta aaagtattga
    65821 gagatgggga agtacatcaa atttctaaga gtgaattggt accaggtgat atagtatata
    65881 ttgaaactgg tgacatggta cctgctgatg gtagacttat agaaagtata aaccttaaaa
    65941 ttagagaaga tatgttaaca ggagaatctg atgacgtatc taaaaagtgt gatgtagtag
    66001 tttctatgga agagatagaa tctaaaggag cagtagtagt acaggaacca atacctgcaa
    66061 aacagataaa tatggtgttt ggtggtacac ttgtagctta tggtagagga gctctagttg
    66121 taacttcaat tggagataat agtgaaatgg gtaaaattgc tcaaaactta tcagaaacag
    66181 atgagcaaac tccacttcag ataaaacttg gaaatttagg tggtttgata gccaaagttt
    66241 ctagtgcagt agcaggatta ctatttatat ttatggtttt ccaaatgata agtaagaatg
    66301 tattaaatgt agatatgtct ggaatattac cgtttttaga atcaatagac ccagttaaaa
    66361 cagcatttac agtatgtgtt gcgttgatag ttgcagcagt gccagaaggt cttccaacta
    66421 tgataaatat gacacttgca ataacaatgc aaaaaatggc taaaataaat gcattggtta
    66481 ctaaaaaaga agcttgtgaa acgataggtt ctgtttctgt aatatgttca gataaaactg
    66541 gtacattaac tgaaaataga atgactgtag aagttgcata tgttgatggc agatatattg
    66601 aaagttcaga agaggaaata aatagttatt ttgaagaaaa ctgtatgata aactctacag
    66661 ctgatgtaga gcacaatgat ggtgatatta agtatttagg aagtgctact gaatgtgcat
    66721 tgcttttata ttacaaaaac gtagattata gacaagttag aaaaaattct aatatagtag
    66781 ctcaaaatcc ttttacttca gattcaaaga gaatgacttc tgttataggt caagataatc
    66841 atcatgtact attatcaaaa ggagcaccag aagtattact tgaattatgt tcacatattc
    66901 aaagaggaaa agacatagtt ccattaactg aaaatataaa acatgagatt ttagaagaaa
    66961 taaagaaatt gcaaataaaa tcaatgagaa ctttagggtt tgcatataaa gaaatctcac
    67021 aagctgaaga agaagcagca gtaactgctg aaagtgatgc tatgaatgta agtgcaatgg
    67081 aaaataattt agtatttagt ggttttgttg gtataagaga cccacttaga aaagatgtta
    67141 tagagtctgt aaatacagca aataaagctg gtgtttctgt aaaaatgctt acaggagata
    67201 atataaatac agcaagagct ataggtgaag agttaggcct attaaaaaat aatatgagag
    67261 tggttgaagc ttcatatata gatactttag atgatgaaga attaaaacaa gagatacaaa
    67321 gtatttcaat cgtggcaaga agtaaaccag atagtaaaat gagaatagtt tcagctctgc
    67381 aaaagagcgg agatgttgtt gcagtaacag gtgatggtat aaatgatgct ccagcacttt
    67441 caaaagcaga tgttggtata gcaatgggta tatctggtac agaggtatct aaaaacgcag
    67501 cagacataat tttaactgat gatagtttta gtaccattgt aaaaggtatt aaatggggta
    67561 gaggaattta tgataacttc caaagattcg ttcaattcca attaactgta aatgtaattg
    67621 catttttagt ggctataata tctcaagtta tgggacaaga gatgccattt actacaatac
    67681 aattattatg ggtaaacatc attatggatg gaccaccagc actagcatta ggtttagagc
    67741 cagttaggga ccatgtgtta aatagaaaac ctgttgatag aaaagccaat ataatttcta
    67801 agtcaatggt gtatacaata gtattaaatg cattttatat aacagcaata ctaatgttac
    67861 aatctacatt taatttctta ggagttgatg aagcgcataa gggaacagta atgtttgcgt
    67921 tatttgcttt tagtgcactg tttaatgcat ttaactgtag agagtttaat gcagatagta
    67981 tcttccctaa ttttacacat aacaaattag cactacaaat aatagtgttg acaggaattg
    68041 cacaagtaat atttactcag ctattccaag atttctttaa ctctgtagca atggatttta
    68101 tgacatgggt aaaagtttta tgtgtagcag caagtgtaat tgtggttaat gaagttgtaa
    68161 aatgtataat aagactggta aaaccaaaaa agactgctta aaacaaattt tttagaagaa
    68221 aacagactga ctcaaaatat gaattttggg tcagttctga ataaacattt aaattgggag
    68281 gatagttatg ggtgactcaa aggtatttga aaaaatattc tccagccaat cagatagagg
    68341 aaattacact ccttcaaagg gatatctaag ttattttatt tcgtatattg gtttagaaga
    68401 tgaagttttg tacaatctcg agatatttaa gacaaaacaa aatattgata gcaaaaaaga
    68461 tattgcttta tttactgatg ttatagcaaa tcctagtgat tttgatatta taaattattt
    68521 taaaagtgga cttcaaaaat atagaactag catggaagat gtagatataa atattttggg
    68581 atttgaagag attgattata aaataaagca agcaatggat agagtgttaa aagaagagga
    68641 aaaagaattt actaatgata gagttaaaca aaattttata gtgaaaataa tggcatggat
    68701 aaaaatttat atcggtgctt tagatataaa taaaaatgaa gctccaaaag taatatttta
    68761 tggagatata aaaaaacatg aagtttattt actcttaata ttatacttgg caggttttga
    68821 tgttttatat cttaatccaa attcaaagag taatataaat attttaaaat cagaaagata
    68881 caatatagag tttgaagaag ccaacataat agaagaaaaa atttcttttg aagaaagggt
    68941 tattttaggg gaaaaaatag ataaaagttc tgtaaaaaaa gcttttactg ttggggcaga
    69001 agcatcaaag cgtataagtg aggaattgtt aaatgatgca ggatttataa aaccttggca
    69061 actccaagat agaaaaataa aaaatctact tctaagttca actgttgatg aaatatcaat
    69121 atactggaat caaccactta aattaagacc aggatttaag tttaatgatg ctattgtaga
    69181 agctccaaat tttctttcta agattaatgg aatatataac gataagaatg aatatattaa
    69241 gtttttagat ttattaagag attcggaaag ttcaacattt attgaattta atggagatgt
    69301 agatagattt tcaaaagctt ttacaagaga agcttttagt ttatcctttt tattggattc
    69361 aaaaggtgca atagataaaa actctgtttt aaataataaa gattattcca tatcaacact
    69421 agcattgaat caacaaatta tgattttaga gaaagtggaa gagttgttag aaggaagtat
    69481 gtttttgaat ggtttaagtg gagaagacaa gataaaaggt ctatttacag tacttcacat
    69541 ggataagaaa tttgttcata tgatgaacaa tttcgattac tcacttataa acccaaaatt
    69601 gattatatac atgtacaaga gtattgtatt tgataaagaa atagtttttc ttatgctttt
    69661 acttagtaag attggatttg atattatcat attatgtcca ggaggagaaa acaatataga
    69721 gaatgttata aataaccaat tgattgatgt acacagattg gataaaatgg tatatgacct
    69781 taaattaaat tcgcttgaaa atgatatacc tttacttaaa aaaatttttg gaaagaggag
    69841 acgattttag atggggataa atataaatag tttttcaaaa gataagaact ctgtagaggt
    69901 tactgagaat ttgcctacag cagttcaaga agaaaacttc gatataatgg aatatacaaa
    69961 taataaaaaa aatgaactga gaaagtctaa ggaagttgag gcattgacat ctcttataga
    70021 agtagaaaat ccagatacga ttttacagtt tggtaggaaa gcatctgaag gagtagcaag
    70081 agtttctgat agccttttaa atacaataaa attaaataga aatgaagaaa attctaaaat
    70141 gctggttcat ttaactaaaa taatggacaa gtttgattta gacgattttc aagaaactaa
    70201 ggaaccaaat ttcgttcaaa aacttttcaa aaaagctaat aatgccattg aaatgatgtt
    70261 tcaaaagtat gaaacattgg gaggagaagt tgagaaaatt caaattgagc ttgaacaata
    70321 cgaaagagat atagcacttt ctaataagca aataggtgct atgttaaatg aaaactttga
    70381 gttttacaat gaacttcaaa aatatattgt tgctggagaa atggcaatag aggaaatgga
    70441 taatgaaata ctacctttct ttaaacaaaa atcagagact agtggagacc aaatggatgt
    70501 tgtcaattat caagaactat taaaagttta tgatatgtta aatcaaagag tatatgattt
    70561 aaggatagca gaaaatatag ctatccaaac aatacctatg cttagaggta tgcaacataa
    70621 taattatggt ttaattagaa aaataaatag tgcatttgtc gtaactttac cagtatttaa
    70681 acaatgttta tctcaagcta tattacttaa aaagcaagaa ttacaagcaa aatctctaaa
    70741 agcacttgat gacaaaacta atgaattatt gcttagaaat gcacaaaatg taagtactca
    70801 aagtgcacaa atagctagaa tggctggaac aagttctgtt caaatagaaa cattggaaaa
    70861 aatgtacaat actatcaaat ctggtataga tgaaactatg agaatagaag aaaacaatag
    70921 agctttaatt aaggataata caaagagatt ggaagaatta aatacgacta taatttataa
    70981 taagtagtat tatattaagg gctaatttgt ataaagttgg ccctttctat gtatatgagg
    71041 aggctagaca ttgaaatatt tcgattatat ctgcaaagat gatttggaga gaattttttt
    71101 gaaggagcca gaagatttta gtgctaagac tgaaaaagat gtgttgaaat atgcactggg
    71161 cgctttttta tacgttccag ctactcaata taatatgatt tataagagta ttatagggga
    71221 tgttaaggga gttagaccat tagctatttg tttagaagat gctgttggag taaatggaga
    71281 gttagaggct atagagaatc ttagattaat tttaaaaaat attagcaatg aaagtataac
    71341 taataaagat ggaataccac taatttttgt aagaataaaa gatgtggagc aactgttgag
    71401 aattaaagag attataatta aaaatagtca ttttataaca ggaatattaa ttcctaaagc
    71461 aaattcggag ttaattgaaa attgtataga agctttagat tctatgaatc ttcaagatat
    71521 gtatgttatt ccgatagtag agacaaaaga atttatatat aatgaaaaaa aagaacttag
    71581 ttttactaat ttgtacaatg ctattttaag acataagtca agaatattaa gcattagagt
    71641 aggcataact gatatattag ggatgtatgg tataaggaga gataaaaact tttctatata
    71701 taataatttg atttgttctt catttatatt agatataatc acatatcttc aaagaccaga
    71761 gttagatata cctataagtg gtggagtatc agaatttttt gatatgacga ataaagatat
    71821 aagaaataag tatatagaag aaatattatt ggataaatat catggattaa ttggaaagac
    71881 cgtaattcat ccaatgcaaa ttcaaattgt acaagcgcta tctacagtat catatgaaga
    71941 ttttactgat gctttggata tactggatag tacagacagt aagtatggtg tgagcaaggg
    72001 tgtattagga gagagaatga atgaaacaaa tccacatttt ttatgggcta aaaaaacatt
    72061 gattctatct aaaatatatg gtgtattaaa taaaggagta gactatgaag aattgcttaa
    72121 attttaattg tgagattgac attattgata atccattgaa tttagaacta aatgattttt
    72181 tagacgtagg aataagaaat aatagcaaaa gacgtttttt gtttatctca aagaaactcg
    72241 gtaaacattt agcatgtaag ccaagtgaga tggataattt gggaaaatta atggctacaa
    72301 tttataatga aaaaaataag gaagaatcaa atggtactgt tatagctttt gctgaaactg
    72361 gtacagctgt tgggcatagt ttttttgatt acttatgtgg agattatgaa tttattcata
    72421 ctactagaga gcagtttgac gagttagaaa atctggaatt tttagaggaa cattcccatg
    72481 caacagacca gaatttatac tttggtatgc ttaacaactt taaatttgga gatgagataa
    72541 tattggttga tgatgagatt accacagcca atacatgcat gaatataatt aggaaaattc
    72601 aaagcattta tcctaaaaag aaatacacta tatgctcaat actcaattgg gtaagtgatg
    72661 aaaatttaag taaagttact cgtttagaaa gagagctaga ttgtaagata gattttgtat
    72721 acttatttaa aggaaacttt aaattttata tagatgaaga tattatttca aattacaacg
    72781 ataattatag tattactaaa ttagagacta tttcaagtga taaagtaaat ttagtagtaa
    72841 atcatattta tgttgattta gaagattata ttggaaataa gaaatatgta aaatatacag
    72901 gaagatttgg aattaataga agagaacaat ttagattaaa agaaatcgtt aagagagaaa
    72961 gtaaaaaaat aactatggcc agtaaagaat ctttaaaaaa tgaaaaagaa aagattctat
    73021 ttttaggtac tgaagaattt atgtatatac ctatgctgtt tgcaaaagaa aaagaaaatc
    73081 aatatgatat atactatcat tcaacaacaa gaagtccaat tattaatatt gataagaagc
    73141 attatcctat taaaagtaaa tttatgctaa agagttttta taatatagat attcaaaatt
    73201 atatttacaa tatagataaa cataattttt ctaagtgtta tttatttgta gagctgaata
    73261 aaagtgaaaa ttcttatcta gaatttattg atataattaa aaaaacaagt ataaaagaat
    73321 taactatagt atgttgtagc taaagtgttt taacaggata aaatatatca cgattttaag
    73381 ataggagttg agtcatatga gagattttag cacgtattct aaagatgatg ttattttttt
    73441 attaaaagat atatcaaatt taattgaaga agaaggaaat aaagaaagag aattaaaaat
    73501 acaaaatggt agacattatt cagaaatgat accaatagag tatgaagtta gtgaagatta
    73561 tctgaattta tatcatgaga aactaagaga aaataaagat aaacttgcat tttctatagg
    73621 agttatgtgt gaaaaaataa ttaaaaaaaa tggaaatgat gtagtactag tttcacttgc
    73681 tagagcagga acacctattg gtattttggc aaaaagatat ataagaagca agtataatat
    73741 aagtttaccc cactatacaa tctctataat aagagataag ggaatagata tgaatgcaat
    73801 tgaatatata gtaaagaatc atccgagctc aaaaattcaa tttttagatg gatggactgg
    73861 taaaggaact atatcaaaag aacttgaaaa agcatgtgat gaacttaatg ttaaatttaa
    73921 aaaatatttt gactcaacac ttgctgtatt agctgaccct gctggatatt caggacttta
    73981 tggaattaga gaagatttct taataccaag tgcatgttta aattcaaccg tttctggttt
    74041 agtaagtaga actgtactaa gagaggattt aattggtaaa aatgactttc atggagctaa
    74101 gttttataga catttaaaag ataaagatga atctatgaac tatatcgaaa ctatagaaga
    74161 atgttttaaa aatcaattta agaatatatc tgatgaagtt gaaaactggg aaagtgacat
    74221 tataacaaga gatggatact ttgatgtttt aaatataaaa gaaaagtata acataacaga
    74281 tattaacttt atcaaaccag gtgtagggga aacgacaagg gttttactta gaagagttcc
    74341 gtataagatt cttgttaaag acttaaatga taaatcttta gaccatatat tcatattagc
    74401 taaggagaaa aatgttgaag ttgaacaaat ggatttaaaa gcctataaat gttgtggaat
    74461 aataaaaaat atgaaagata tttaggaaat atattagaca ggagaatatt gaatgattgt
    74521 tttttcagat ttagacagga gtatcattta ctccaataaa tttttaaatg ctgatagtaa
    74581 atatgctaat atagaaattt atagggaaaa agaaatatct tatatatctt tagatactat
    74641 aaatttaata aagcaaatac aatattatgg tatgtttata cctacaacta ctagaacagt
    74701 ggagcaattt aagcgtatag aatttaataa atatgggatt tattttcctt ggagtataac
    74761 ttcaaatgga ggagttatac ttaaagataa tgaaatattg aaatcatgga gtgaaaaaat
    74821 agataaacta aaatctgatt atgagcccat tgaaagtatg attcataaat ttaaagacta
    74881 tttgaatgta gatggaataa ctaattttaa agttgcagaa gatacatttt tttatatagt
    74941 tgttgattta tcaagattta atttggattc aatcaaagaa tatacaaata tattggaatc
    75001 aaaaaattgg aagttttatg tgagtggcag aaaaatatat tttataccaa aagaaatttc
    75061 aaaagaaaat gctataaaat acttgactaa agaattagga atagaatatt tttatgcagt
    75121 tggagattct attatggact atggtatgct taatatctca aataaatcct atgtattgaa
    75181 gcatggtgat ataaataaaa atgaaataga aaattcattt atatcaagtt ctttcaatgg
    75241 aatgagtgga actgaagaga tactatctaa cattttagac gagaactgcc tacttaacat
    75301 ataatgactg atatataaat aataaactag aaaaatctga aataaattat agtaaagttt
    75361 atcatactaa tttatttcag atttttatca atttatattt aagtaagaac tcaatatgtt
    75421 aaaatgaagg tggagtcatt gcccagactg agatacatac ctcatcatca taattttcat
    75481 acacatgtgg tatagtactg ttaaaataaa aactatctcc ttcctccaat agatattcct
    75541 tatttccaag tgttatcttc attttacctt ttattatata gccacattct tctccttcgt
    75601 gtgtcacaaa ttcactgttt ttttgtgtat gaccatctag cgtaacaagt ataaattcta
    75661 tttttttccc agataaatta ggaacaagaa gttcataaaa ttttgtagaa tcattagtta
    75721 ctattttttt tcgattattt ttctttacta ctatatcaga gtcttctctt ccaatctctt
    75781 caaaaaaata acctatattt atatcaagag cttttgatat tttccacatt gctacaatag
    75841 atggaacaac catattacgc tcaatttgac ttattaagcc tgtacttaaa tctgaatttt
    75901 ttgctaaagt agagatactt atatttttag attttctaag agatctaatt ttgcttccaa
    75961 catctatatt cattagatac aaaccccctc agacatgatt ataacatata atttataaag
    76021 attaataaaa taaaaaaaaa gttttacaat acaagtattt tttatgctat attgaatttt
    76081 ctgaaaagat gcattataat agtattaata ttcaatatat tgaatattga taacgatatt
    76141 ttaatttaat gaaatggagg taattaagat gaagagtttt gtaagtcctg ataatatttg
    76201 ggtattatgg gcagttgtaa ctggatgggc agcatttagt atttatttgg aacaaaagta
    76261 caattgggca tcaaaagtgt cgggagcaat aatagctctt gtaggagcaa tgttattatc
    76321 aaatctaaat attataccag tagagtctgt tgtatatgac caagtatggg gatatgttgt
    76381 tcctttagcc atagctttat tgttatatca atgtaacatt aaaaagatat ggaaagaaag
    76441 tggaagattg ctcattatat ttcttgtagg ttctgtagga actgtacttg gagctatgat
    76501 tggattttta gcattaaaaa atgtagtacc agatttaaat attgttgcag ctatgatgac
    76561 aggttcttat ataggtggaa atgtaaactt tgctgctatg tcaggggcgt ttgatgcgcc
    76621 aggagaatta gtatcagcaa cagttgtagc agataatctt ttaatggcat tatatttctt
    76681 tgtcttaata gctataccat caattggatt ttttagaaaa cattttaaac atccacatgt
    76741 agatgaaatg gaaagtatag gtataactga aggagaaaca gtagcagcaa attattgggg
    76801 aagaaaagaa atatctttaa aagatatagc aatagccatt ggtagcgcct ttataattgt
    76861 cgcagtatct gtagaactat caacttggtt taaagctata ataccattat caaatccttt
    76921 tttagcaatg ttaaatactt tatttggaaa tcaatatcta ataataacta ctttgactat
    76981 gttgtttgcc acatttatgc ctaatttctt tggtgatata aaaggagcac aggaattggg
    77041 tacattttta atatatatat tctttgttgt agtaggtgtt cctgcttcaa taacattaat
    77101 aattcaaaaa tcaccattac tacttttata ctgcggaata atggtactaa taaacatgct
    77161 agttacattt atagttgcaa aaatatttaa gtttagttta gaagaagcta ttcttgcatc
    77221 taatgcaaat attggtggtc ctacaacagc agcagctatg gcaatatcaa aaggatggtc
    77281 taagctagta gggccaatac ttatagttgg aacatttgga tacatagttg gtaattattt
    77341 tggtctttta gtaggaaata ttttgatata attttacgtg aaaaaaagtt gttttttaga
    77401 aagattttta ttttttagaa agatttttat ttaattggag gttgttatga ttttcgatgg
    77461 acattcagat acttgggcag atgtaacaat aagaaggctt aacggggaaa aagatgtatt
    77521 tagaagaatc catcttgata attttaaaag agcaaatata gaaggagcta tttttgtaat
    77581 atggatagac ccaccatatg ataaagagcc tgaaaaaaga gttaaacaaa ttataagctc
    77641 tataaaagat gaaattgaag atatgaaaga tgttgtaaac atagtaaaaa aatattcaga
    77701 tatagataaa ggtataagtg aaaacaaaat aaatatttta attggtcttg aaggattaag
    77761 ccatattgga agaaatatag atttactaga ttatttttat aaagaagttg gtgcaagaca
    77821 tgcatcatta acttggaatg aacagaatga acttgctaca ggatgtttag gggatgaaaa
    77881 tcgtggttta actgaaatag gtaaaaaagc agtcaataaa atggaaaaat tgggcatgat
    77941 agtagatgtg tcacatttaa atgaaaaatc attttgggat ttaatgtctg ttgcaagtaa
    78001 gccagttata gcttctcatt ctaatgctag gagtttatgt gatgctaaaa gaaatcttac
    78061 agataatcaa ttaaaagaaa tttcaaatac aggtggatta gttggaataa atagttttag
    78121 aggatttact aatagtaatc ctaagaagca agatttaata catttggttg accatataga
    78181 ctatatggta aatcttatag gtatggaaca tgtatctttt ggttttgatt ttagtgatta
    78241 cttagggaaa gagactatag gttcttttac tggaaatgct agtgtgccaa gtgtagatgg
    78301 tcttgaaagc acacatacag cacagaacat agtagtagag cttgaaaata gaggttataa
    78361 aaagaaagat atagagttaa tctctagtgg taatttttat aggctcttta aagatatact
    78421 aaaataatat aataaagaac ttaaatttat aaaatagtat atttatacaa ataatatcta
    78481 catatttaaa ttggcgttca taatttatta aattaaattt taatgttact agaagtttca
    78541 attctagtaa cattttttat gttaaaaaca gatatagata tgtattgaca atgataatta
    78601 ttattgataa actataaaag tgaaaatgat aataattttc attttaatta ataaaagatt
    78661 tttaaggagg gagaatgaag aaaaggtatt tagtcatagg aataataatt ttgtcttatt
    78721 tttctttatt tataggagct gaagatataa atataatgca tatatttgca aaaaatcagc
    78781 ataaacttat gatatttatc atgagtagaa taccaagatt aataagtata ttgattgctg
    78841 gtgtaggaat gagcatagca ggtcttataa tgcaacagat aagtaagaat aaatttgtat
    78901 cacctacaac aggtgctaca atagatgcag cacaatttgg gatagtaata tgtatgcttt
    78961 tagtaccaac tgcctctatt tttacaaaga caataatagc atttgtattt tctcttgtag
    79021 ggacttttac gtttatgaaa ataataggga agttacaatt taaaaatata atctttgtac
    79081 cattagtagg tataatgttt ggaaatataa taggttctat gacggatttt atcgcgtata
    79141 aatacgattt gagtcaaaat gttagttctt ggatgcaagg tgacttttct atgatactta
    79201 aaggaaatta tgagatatta tatatcacaa taccccttat aatattagca tatatttatg
    79261 caaataaatt tactgttgtt ggtatgggta tggattttgc gacaaattta ggtcttagtt
    79321 acaaaagaat tgtcaatata ggtctgataa tagtagcact tgttacagta tgtgtagtcg
    79381 ttacagctgg taatatccct tttataggtc taatagttcc aaatatcgta tccttgtaca
    79441 tgggtgataa tataagagca agcatatggt atactggttt acttggagcg atatttgtac
    79501 ttatatgtga tatttttgga agaattatta tttatccata tgaaatatct atagggctta
    79561 cagttggagt tataggaagt atactattcc tttatttaat attaaggagg aatgtgaatg
    79621 aagcttagtc tcaatcaaaa aatttacttt gtaagtatat tactattcat atcaatagca
    79681 ctttttataa tttatggaat agacatgaat catttagaat atgcattatc acaaagaata
    79741 ccaaaaatat ttgctatggt attaggtgga ggatgtatag catttactac tgtagtgttt
    79801 caaacaatta caaacaatca aatattaaca ccaagtgtac taggtttaga ttcattgtat
    79861 gtaatgattc aaactataat agtattcata tttggttcaa gcagtagtct gattataaat
    79921 gaaaattata attttattat taatgtagct atgatgattg gagcttcatt gttattatat
    79981 aagacgttat ttgaaaaaaa taaaaataat attttctttt taatcctagt aggaatgata
    80041 tttggaacct tatttaaaag tgcaacaaca tttattcagg taatgataga cccgaatgaa
    80101 tttttagctt tacaaactag tataatggca agtttaaaca atataaacac taatgtattg
    80161 ttaatagcat ttataataat tattgccata atacctttta tatatgatga aataaagtat
    80221 ttagatgtat tgtcgttagg taaagaacaa gcaattaatt taggtgtaga ttttgataaa
    80281 gcagttaaaa aaatgataat attaatagca attttagtct caatatcaac agcacttatt
    80341 ggacctatga catttttagg acttttactt gctaatataa caagagaaat ttttaaaaca
    80401 tataagcata catacttgat ttcgggttct atgttgatag ggatgattac attgataata
    80461 ggtcaatttt ttatacaaca tgtatttaag tttgatacaa ctttaagtgt agtaataaat
    80521 tttataggag gaatttactt tattcaatta ctattaaagg gggcaaatag atgatagaga
    80581 taaaaaatat atttaaaaga tataagaata aaaatgttgt agatgatgtc tcttttagta
    80641 tagaaaaggg aaagataaca tcttttatag ggccaaatgg agctgggaaa agtacagtac
    80701 tatcaatagt tacaaggctt ataggaggtg atggtggaga agtaataata gaaggaaaaa
    80761 gcttgactaa ttatagcaat aaagaattag caaaaaaaat agctattctt aaacaatcta
    80821 acaatataac tttaaagctt acaataagag aattagttgg atttggaaga tttccatata
    80881 gtgaaggtaa tctaactaaa gaggatgaaa attatattga tgaagcaata gaatatatga
    80941 agttgactga tatacaacat aagtatttag atgaattgag tggaggtcaa agacaaagag
    81001 cttatatagc aatggtaata gctcaagata cagagtacat attacttgat gaaccactga
    81061 acaatttgga tatgaaccat tccgtacaga tgatgaaggt acttagaagt ctttgtgatg
    81121 agttagataa gactatagta ttagtaatgc atgatataaa ttttgcatca tgttattcag
    81181 ataatatagt tgcattaaaa aatggaaaag ttgaaaaagt aggtcgtaca gatgagatag
    81241 taaatgaaaa agttttagaa gatatttatg agatgaattt taacattaag aatataaatg
    81301 gaaatcgaat ctgtatttat ttttaaaata ttgtatatga aaataaactt gctatatgat
    81361 tttttataaa gtttttaaat taaaataaag attaatagga gagaggaaaa tattgatatg
    81421 aataaaaaag cagcaatagt agcagcagta gctattatag gattagtgac agtgtttgca
    81481 ttaggtggaa gtaaaaagaa tgaatcaaaa acatcagaaa attcaaataa taccatgaag
    81541 ataactcata acttgggaga aacagatgta aaattaaatc ctaaaaaagt agtggtattt
    81601 gattattcgg ctttagatac aatggatgca ttaggtgtag ctgagaattt agtaggactt
    81661 ccaaaagcga gtttaccagc atccttagaa aaatataagg atgacaagta tgcagattta
    81721 ggaggattaa aagaaccaga tttagagggt ataaagtcgg caaatccaga tttaattata
    81781 ataaatggaa gacaagaaga tttttatgag caattgtcaa aaatagcacc aacaataagt
    81841 acaagtaaag atgataagaa gtacttagaa tctgttaaaa ataatataga caaaatagca
    81901 aaaatatttg gagtagaaga aaaagcaaat caagaattta gtaaaattga aaagaaaata
    81961 gaaactttga ataaaaaagt aacagataaa aatttaaatg ctttaactat aatggtaaat
    82021 gaaggtaatt taagtgtatt tggtgaagaa tcaagattta gtatattata caatagtttt
    82081 ggatttgaaa ataaagataa aaatataaaa gaatcaagtc atggacaaaa tattactttt
    82141 gaatatatag ctaaacaaaa tccagaagtt atgttcgtta tagatagagg aatagctact
    82201 ggcagtgatg taaaagaaag ctcaactgca aaatctgttt tgaacaatga tataataaaa
    82261 tctatggatg catataagaa tgataatata atatatttag attcaccaac atggtatgta
    82321 aatgatggtg gtctaacatc tttaaataaa atgatagatg atgcttcaaa agcggtaaat
    82381 taataatccg atataatcaa aatgtatttt ttataaaatg attatcaaat aaactaggag
    82441 tttttaagga ctcctagttt attttttgca taagaaaaat atagtttaaa caataatatt
    82501 atttacaata agataaatct attcaaaatc taataaaata tgaagttata ctagacaaaa
    82561 agaataattc tt
//
LOCUS       DAEORM030000012        79034 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.012, whole genome shotgun sequence.
ACCESSION   DAEORM030000012 DAEORM030000000
VERSION     DAEORM030000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 79034)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 79034)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 79034)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..79034
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.012"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            126..1406
                     /locus_tag="KRH23_001173"
     CDS             126..1406
                     /locus_tag="KRH23_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HHS5224462.1"
                     /translation="MNILGLIVEYNPFHNGHIYHLSKSIEKTNATHTVAIMSGNFLQR
                     GEPALFDKYTRAKIAVENGVDLVIELPTLFACQSAEIFSHGAITILNSLNCINSICFG
                     SEEGNTEILYNIAEILANEPNEFKLLLKKYLDDGLLFPTARANALFDYIHQDKKNNFI
                     QNYSKEQLSKTLNSSNNILGIEYIKNLIHLNSSIKPFTISRVQSEYNSEEIESDICSA
                     TAIRTSLKENTDLFHLKNVIPEKTYNILNEKIDNGFLPMFDDFFFDILKTIILRDMDT
                     LKEYFEVNEGIENRIYKDIFTSEFLHELQLAIKSKRYTLTKIKRTLNNILLGIKKSDM
                     QLIKNIDTIPYIRMLAFNDKGREILKEIKNKSEIKIINKFSNISFSLDDTIFKTLISY
                     DIKATNIYNSIYYKNNKDLVKGPMDFYTHPIYVK"
     gene            complement(1669..3060)
                     /locus_tag="KRH23_001174"
     CDS             complement(1669..3060)
                     /locus_tag="KRH23_001174"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HHS5224463.1"
                     /translation="MYKLIDKKDIDFLIDTCGEENVLVGSDINEDFSHDELGGIEKYP
                     EVLVNVLETEQVSKIMKYAYKNNIPVTPRGQGTGLVGAAVAINGGIMINLCKMNKILE
                     VDYENLTLTVEPGVLLMTIGQYVQDRDLFYPPDPGEKSATIAGNINTNAGGMRAVKYG
                     VTRDYVRGLEVVLPNGEIINVGGKVVKNSSGYSIKDLLVGSEGTLGIVTKAILKLLPL
                     PKKSISLLIPFPDLSMAIETVPKIIKSKSIPTAIEFMERDVILAAEEFLGKKFPDNTS
                     DAYLLLTFDGNSTEDIEKEYEKVANLCLENGALDVFISDTQERNDSIWSARGAFLEAI
                     KASTTQMDECDVVVPRDKIAEFIRYTHELQDKLKIRIKSFGHAGDGNLHIYILKDGMD
                     DNTWKIRLKETFDYMYKKSRELSGQVSGEHGIGYAKKEYLHESNSDAYMMLIKNIKLA
                     FDPKNILNPGKIY"
     gene            complement(3071..4291)
                     /locus_tag="KRH23_001175"
     CDS             complement(3071..4291)
                     /locus_tag="KRH23_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding protein"
                     /protein_id="HHS5224464.1"
                     /translation="MSKIVVNQDKITDLKRILEICPFGAIEEKSGIVEISAGCKMCKL
                     CVKSGPKGAFEFIESSKVQINKDEWRGIAVYVEHHNGNIHPVTYELIGKAREMASKIK
                     QPVYCVFVGKDIKDKCSNLISYGVDEVFVYDEDEFKDFRIEPYSKAIENFIDKIKPTI
                     VLVGGTTLGRSLAPRLAARFRTGLTADCTILDIQSNTDLDQIRPAFGGNIMAHINTPN
                     NRPQFATVRYKIFSAPEKIENTTGKITLCKVEKKELKSKIKVLSVKEKNKEVGLEEAE
                     VIVVASRAIKKQEDMEMIYKLADKLNAQVAGTRPVIEAGWIDAKKQIGLSGRTVKPKL
                     IITCGVSGAVQFVAGMQGADYIVAINKDDKAPILDVAHLALIGDIYDIIPKLIEKIEN
                     NKDNNQKYMASAAK"
     gene            complement(4305..5093)
                     /locus_tag="KRH23_001176"
     CDS             complement(4305..5093)
                     /locus_tag="KRH23_001176"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta/FixA
                     family protein"
                     /protein_id="HHS5224465.1"
                     /translation="MEILTCIKQVPGTTSVEVDETTGVLKRDGVDSKMNPYDLYALET
                     ALRIKEEKKANLKVLSMGPPQAKKVIEESFMMGADEGVLISDRRFGGADVLATSYTIS
                     QGIKKMGKVDLIICGKQTTDGDTAQVGPEVAEFLDIPHVTNVTKLIEVKDESIVVEID
                     MPNDLQVCEIEYPCLITVEKDIFQPRLPSFKLKLNTKDREIPVYSLDDFEDKDENNYG
                     LNGSPTQVVRIFPPKPNTDKNIVRGNADELSFALVNKLEELKLV"
     gene            complement(5110..6384)
                     /gene="larA"
                     /locus_tag="KRH23_001177"
     CDS             complement(5110..6384)
                     /gene="larA"
                     /locus_tag="KRH23_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050043 - lactate racemase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nickel-dependent lactate racemase"
                     /protein_id="HHS5224466.1"
                     /translation="MVKLKVPYSKQGMILEIPDERFLGVLESKSDNYIEHKTQEEIVE
                     ESMNNPIGSNSLEELVKGKKNVVIITSDHTRPVPSRITMPIILRRIRNVNPEIDVKII
                     VATGFHRPSTREELIYKMGEEIVDNEDIVMHISTDDKSMCKVGILPSGGDLYINKLAY
                     EAELLIAEGFIEPHFFAGFSGGRKSVLPGIASAKTIMYNHCSDFIDSDNSRTGKLNNN
                     PIHEDMVYAAKVAKLAFILNVVIDKDKKIIASFAGDVEKAHTKGCRFVTELSKVNSIK
                     SDIVVTTNGGYPLDQNIYQSVKGMTAAEATCKDGGVIIMISACNDGHGGQSFYENVAN
                     ADSPKQLLDKIRSVDRVDTIPDQWEFQILARILSKYTVIMVTDKCNPEMIKKMHMKHA
                     FNFKEALEMATSIVGKESKVVVIPDGVSVIVK"
     gene            complement(6502..7215)
                     /locus_tag="KRH23_001178"
     CDS             complement(6502..7215)
                     /locus_tag="KRH23_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FadR/GntR family transcriptional regulator"
                     /protein_id="HHS5224467.1"
                     /translation="MFNSIASKKVYEQVIEQIQYKILNGELKKGDKLLSERELSEQMN
                     VSRTSIREAIRVLETMGVIESRQGEGNFICTNIEKTLIEPLSMIFKLNNGTLEDILEL
                     RIILEIEIAKLASKRITSSEVIELKHIIDEMRVETNKKDNNRVLVLLDQKFHSKLATL
                     SKNYLIQSLFMTASKLFDGFIEDAREKIIAEPFNENILLKQHEAIYNAVVENDVELAC
                     EKAKEHMDFISKNYRKNEN"
     gene            7340..8599
                     /locus_tag="KRH23_001179"
     CDS             7340..8599
                     /locus_tag="KRH23_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation integral membrane protein YlbJ"
                     /protein_id="HHS5224468.1"
                     /translation="MKKNKIIAFFAPSIIVGVLVLGIILYPNEAIKSAREGFSIWSNV
                     LVPSLLPFIIGANLIVDLKIVDIIGFIINPITRFVFNVSGKSALAFAISTVSGYPVGV
                     SLASEFRSNGQISKYEAQRLVSFCSTSGPLFIIGSVGTGMFQNSNLGYLMILCHYLGT
                     ILVGLFFRNYGNENLPKTKLDLKTNIKNVINIRNSSGNGFFVLFGNAVFNGVNTLLTV
                     GGFVIVFSVVFKILSLFNVISLIASVIYLPLSFLGVSKELCQAFVSGLFEITIGCNKV
                     SSITSSPEILRASLASFLIGFSGLSILAQCCTFLSKTDIDLKLYILSKFAHGVLAAIF
                     IFILYPIANSAVLVSSFADTYNVIYNNLIWFYYLSYYDTILQIVVIIYLISAVFIAKK
                     HMKTLSTNGKLMRYKNTFFTKKFSRKK"
     gene            8867..9433
                     /locus_tag="KRH23_001180"
     CDS             8867..9433
                     /locus_tag="KRH23_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HHS5224469.1"
                     /translation="MATRPIEIDEYKKIMELLHTGFTYSENGVEKRFRKNPKVALALM
                     LEANLGLRISDILRLKIGNFKGNMLEINEKKTGKLQYRPVNKNIIESINEHARKYNLK
                     SNDYLVNIKTKAIQKQLRIICKHLNLYNISTHSFRKLYATTQFEKSNNNLELVKELLN
                     HSSVATTQRYIRVTQQAINEASENFFIG"
     gene            complement(9634..10839)
                     /locus_tag="KRH23_001181"
     CDS             complement(9634..10839)
                     /locus_tag="KRH23_001181"
                     /EC_number="1.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004412 - homoserine dehydrogenase
                     activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HHS5224470.1"
                     /translation="MKIALLGYGTVGSGLIDLIENNTSKRDIEVVGILVKNKEKHKYK
                     KYFDKITTDIEDIFDKDIDILVEVIGGLNPAFDYVTRALNKKIHVVTANKDLLAEKGS
                     DLIELANLNNVSIKFEASVAGGIPVLKPLIESLEGNNIKSINAILNGTCNFILSKMYD
                     ENLPYDVALKQAQELGFAEVNPDADVLGYDSARKLSILSTLSYGKIVYWKDLLLEGIT
                     SIDEKDIEYAKKLNCKIKLVARSKYESGEVSGFVRPALVDNNNMLSKIDNEFNVVILV
                     GDSVGELSFVGKGAGRGATGSAVYADIIDIIDNRSSNIKSFSKGKLDLSGLIEDECSA
                     VVRFGGYNNKDGILECLDKYVDSYDIIDDEELAIFVSAKSEHEIDRVLEIVKRNNYSE
                     SAKKLLKID"
     regulatory      complement(10942..11048)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            complement(11140..11508)
                     /locus_tag="KRH23_001182"
     CDS             complement(11140..11508)
                     /locus_tag="KRH23_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YhbY family RNA-binding protein"
                     /protein_id="HHS5224471.1"
                     /translation="MLKGKQRAYLRSLANTLKPTTQIGKEGVTESFLEQLDGMLRTRE
                     LVKVTILENAGLDTKETANAVCEALRAEFVQAIGFKFTIYKRNIEEPKILFPGHEQAK
                     AKTKNNNVTKKGKPTKRAVR"
     gene            complement(11560..12837)
                     /gene="obgE"
                     /locus_tag="KRH23_001183"
     CDS             complement(11560..12837)
                     /gene="obgE"
                     /locus_tag="KRH23_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HHS5224472.1"
                     /translation="MFIDKARIFVKAGNGGNGSVAFRREKYVPAGGPDGGDGGRGASI
                     IFEVDLGLRTLMDFKYQKKYQAQNGGDGSKGKRAGKNGENLVLKVPAGTVIRDEATGL
                     VLADLKKEGDTAIVAKGGIGGKGNQHFANAVRQAPAFAKSGTDGEERWITLELKMIAD
                     VGLLGFPNVGKSTFLSVVTKAKPKIANYHFTTLTPNLGVVQTKFGDSFVLADIPGIIE
                     GASEGIGLGHEFLRHVERTKVLIHIVDISGLEGRDPIEDFDKINDELKLYNEKLSKRP
                     QVVVANKFDILEDESKFEKFKSELEGRGYTVFKMSAATRQGIDEVIAYVSKMLKEVED
                     VELVSEEEMYRPELDIGTEEELSIDIEDGVYVVTGKALRRIMYSVNFDDMESLQYFQK
                     AMESQGVFDRLREMGIEDGDVVKIYELEFEFYN"
     gene            complement(12948..13238)
                     /gene="rpmA"
                     /locus_tag="KRH23_001184"
     CDS             complement(12948..13238)
                     /gene="rpmA"
                     /locus_tag="KRH23_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HHS5224473.1"
                     /translation="MLNMNLQLLASKKGVGSSKNGRDSISKRLGVKRFDGQLVTAGSI
                     IVRQRGTKIHPGTNVGKGSDDTLFALVDGTVKFERKDKKRKKVSIYPVAIAE"
     gene            complement(13252..13569)
                     /locus_tag="KRH23_001185"
     CDS             complement(13252..13569)
                     /locus_tag="KRH23_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HHS5224474.1"
                     /translation="MIKVKYYYNDDFLLQGFCLKGHADFAEIGYDIVCAAVTSNAIAV
                     INSLDKLQKIEFEKVVGEEGHIECIVKDTHVKDAQLLLNHFQLAVKEIKREYPKNIKI
                     LKK"
     gene            complement(13584..13895)
                     /gene="rplU"
                     /locus_tag="KRH23_001186"
     CDS             complement(13584..13895)
                     /gene="rplU"
                     /locus_tag="KRH23_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012063435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HHS5224475.1"
                     /translation="MYAIVKTGGKQYKVSEGDVLFVEKLEANAGDVVTLNEVLACSKD
                     GELKLGSPVVEGASVQAKVVEQGKAKKVIVFKYKAKKDYRRKQGHRQSYTKIVVEKIN
                     A"
     gene            complement(13996..15417)
                     /locus_tag="KRH23_001187"
     CDS             complement(13996..15417)
                     /locus_tag="KRH23_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Rne/Rng family ribonuclease"
                     /protein_id="HHS5224476.1"
                     /translation="MKKIVIESLIGSQKTAVLEDERLTELFVEDNLNKKTVSNIYRGI
                     VKKVIPGIEACFVDIGFKKLAYLQLKKGSTIKSGQDILVQINKEEIGTKGAKLNTEIS
                     ISGRYIVYIPSNDRTTISNKITDEKERFRLKKITKAVNKENLGLIIRTEAQGCTHDEI
                     KKDIEELKLKYENILKEYKLGIGPKLLYKSLDFATKYVKDNVNDDIESIITNSYDKYS
                     ELKSILRGIDKTYVDKLCLEENRDVFDLYRIESKIEKLLNKKVWLKSGGYLIIEKTEA
                     LTVIDVNTGKFIGTGKLDETVYKTNLEAAKEIVRQLRIRDIAGIIIIDFIDMHKKKHQ
                     KEILHILEEEFNKDKRKVEVLGMTKLGLVEVARRREKESIDKYYLMSCPCCDGEQTIK
                     SVHYILDSIEKEIMRISEHTVYKNIMVEFNDFIFEQIKEYYMDIIDKIGEKYNIKISL
                     NANSTLKHNKTNVIFDKIVDNKM"
     gene            complement(15435..16136)
                     /locus_tag="KRH23_001188"
     CDS             complement(15435..16136)
                     /locus_tag="KRH23_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03936 family radical SAM-associated protein"
                     /protein_id="HHS5224477.1"
                     /translation="MSKIIRVKFKKEGDMIYISHLDLQRLLQRAFRRAEINLSHSQGF
                     NPHPKMSYGNALALGTESQGEYVDIEIEEDDLSVEEFLNKVSIQLPDGIDFIKAKEID
                     RQTPSLSSVIDYGEYLFNIDLKRPMTKEFVKRKVIDFMNNKEIIITKKNKKGKMVEVD
                     IRPMIRTFDVLNLEDEHITLTATIATGSKTNLNTNILIPKILEMFELDIDPLDVDILR
                     RDLYVLEDGELVTPM"
     gene            complement(16138..17982)
                     /locus_tag="KRH23_001189"
     CDS             complement(16138..17982)
                     /locus_tag="KRH23_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03960 family B12-binding radical SAM
                     protein"
                     /protein_id="HHS5224478.1"
                     /translation="MNKVDLKKILKKVEKPARYLGNEINSIHKDTSNSELIRYAHCFP
                     DLYEVGMSHLGSHILYDVINKDEDVFCERVYSPAVDMENIMREKSIPLFALESREPIT
                     NFDFVTFTLQYELSYTNILNILDLANIPILKEERTLKDPFIMVGGPCAYNSEPLADFV
                     DVVILGEGEEVNLEVVNEYKEWKKNKTTREDFLYKISSIEGVYIPSFYDVKYNEDGTV
                     QSVTPNRDGITKNPTKRIIKDVETVDYPEKLIVPYIDTVHDRIVLELFRGCTRGCRFC
                     QAGMIYRPIREKSVKRLKEILDKLVKNTGYDEISLSSLSTSDYSKLSELTDYLVDEYA
                     SNNIGISLPSLRLDNFSMEIADKIQQVRKSGLTFAPEAGTQRLRDVINKGVTEEDLEN
                     ATERAFEMGWNSVKLYFMIGLPTETYEDLDGIAKLAYKVIDIYRKVNGGKLKRSFSVT
                     VSTSTFVPKPFTPFQWHGQDTTEEVINKQRHLVNKLRNNNIKYNYHDSKTSLMEAVVA
                     RGDRRIGKVIYDAFRLGAKFDGWAEHFNLDIWKEAMEKNNLSIDFYAHRNRNYEEVFP
                     WDHIDVGISKKFLIREDENAKKEKITSDCRHNCNGCGINIHDIGRGLC"
     gene            18301..19494
                     /locus_tag="KRH23_001190"
     CDS             18301..19494
                     /locus_tag="KRH23_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FprA family A-type flavoprotein"
                     /protein_id="HHS5224479.1"
                     /translation="MSKVFEVKKDIYFTGVVDEGLKVFDIIMETEFGTTYNSYLIKDE
                     KTVLFDTVKANFKDEFLSNLSEVTDIAKIDYVVIHHTEPDHAGSLKYLLDINPNIEVY
                     CTKAAKLYLDGQINRPFNCHVIKDGEILNIGKRNLRFITAPFLHWVDTMFTYIEEDKT
                     LLTCDAFGCHFASVDAEVVNSEDYLKSAKHYYDCIVKPFAKHVLSAVDKVVGLNIEFD
                     TILTSHGPMLTKDPMAAVKRYVEWSTEAVNTTNQNQVSIFYLSAYSNTLEMAKKIKEG
                     LDKEGAKAELYDLEDMTLTEMHDTLVVSKVILLGSPTINKTMVKPMWDLFSVIDPMAN
                     QGKIAGVFGSFGWSGEGITMAETLLKSMSFKMPVESLKKKFFPSEETLKECMAFGAEF
                     AKLVK"
     gene            complement(19706..20788)
                     /locus_tag="KRH23_001191"
     CDS             complement(19706..20788)
                     /locus_tag="KRH23_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
                     /protein_id="HHS5224480.1"
                     /translation="MKKIRKLATKLLIAMMVLTSCMSVTVYGMTAKDVTAKTPKSYVA
                     GTNSIYGPKLSQAQLNSVAQATADFMNKKITKNMTTDAKIRVAYNHIKNNTTYVNWNA
                     AEGANTAYTLVTKKGACSGMCRSLKALCDVMGIECYYVHSTTNDHQWNLIRFEDGRLY
                     HVDIDANKSAGADIIYKSLTHPLPFDKKAYPAVGEVVKTQNPTPTVKKPTPAKPSAPV
                     GPGNQTMIADQEGSILNEVYGNNMKPQNKMYEGVPCSSIDSSINTIKFTSSNSNLDPS
                     KHTVYVIGFKKTQYGMVALAPESKPVSYPFEYDKPFSLDFTGKNRSAAELSKYCKKNN
                     IIIKVEIGETASNSGRGMVAYARYVN"
     gene            complement(21352..22143)
                     /locus_tag="KRH23_001192"
     CDS             complement(21352..22143)
                     /locus_tag="KRH23_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease prefix domain 1-containing protein"
                     /protein_id="HHS5224481.1"
                     /translation="MKLIDEYLDKLYKKCDNKSTIELKQEMRCHLIESANEFKLEGLD
                     EEEACKKAIERFDDGDEMQYELCNIIKELSLSLDRHKSIVMGFKKVLGYISIIAFLIS
                     GFMWYYNNSLQHNMYNLGKELDGEIKQLAERHDMTKIGEYKLELEKILDKDKYSKVKA
                     LRLYVIDMKDGNTNLSSSGLNANMVYESEADYNNISNFIQHLGYNGKDFLDKNGNIVN
                     PDIFLEYFFYFESEMLIPVAFVFGLLCIIAYFILRFKISLIKNNN"
     gene            complement(22147..22476)
                     /locus_tag="KRH23_001193"
     CDS             complement(22147..22476)
                     /locus_tag="KRH23_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HHS5224482.1"
                     /translation="MQLNKEVLKGYIDILIVSILEKKDCYGYEIAKQVRERSEFELKE
                     GTMYLALKRMESKNLIKSYYSNEQSSGGRRKYYNLTNEGKDFLEIKKQEWRFIKKVMN
                     QFLGEVD"
     gene            complement(22961..23374)
                     /locus_tag="KRH23_001194"
     CDS             complement(22961..23374)
                     /locus_tag="KRH23_001194"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008929 - methylglyoxal synthase activity
                     [Evidence IEA];
                     GO_process: GO:0019242 - methylglyoxal biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HHS5224483.1"
                     /translation="MNIALVAHDQMKNTMVGFCIGYESILKKYGLYATGTTGKRIMDE
                     TELNINRLASGPLGGDQQIGSLIVTQEIDLVIFLRDPLTSQAHETDIQALIRLCDVYH
                     VPIATNLASAEIFIKALDRGELSWREVRKSKSQRI"
     gene            complement(23415..24545)
                     /gene="rodA"
                     /locus_tag="KRH23_001195"
     CDS             complement(23415..24545)
                     /gene="rodA"
                     /locus_tag="KRH23_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein RodA"
                     /protein_id="HHS5224484.1"
                     /translation="MKKININYKSTIKLIKQLDWKLIVTVLAIFIFGLVILSSATHAN
                     STGSYNQLIKQGLAFVLGIGMIIVILFFDYNLLGRYYKALYIISLILLAIVLLPGIGT
                     VKGGARSWINLGPLDLQTSEIVKLTFVLSYAKILESKKDKLNTLKEVMPVVVYSLPFI
                     GLLIAQPDLGTGIVFCCMIFAMLFTAGLSSKLIKRGIIILLVSMPLMYLMMADHQKIR
                     IEAFLNPEDVTLKGNYQVMQSLIAIGSGGVTGKGLYNGSQNQEDFLPVQDSDFIFAVV
                     GEELGVIGMAVLIILFMIFLLRLLAIARDAKDFYGTLIVVGVMGMFGYQIIQNIGMTV
                     ALIPVTGVTLPFVSYGGSSLLTSLANLGLVLNVCMRRKKINF"
     gene            complement(24630..24914)
                     /gene="minE"
                     /locus_tag="KRH23_001196"
     CDS             complement(24630..24914)
                     /gene="minE"
                     /locus_tag="KRH23_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0032955 - regulation of division septum
                     assembly [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division topological specificity factor
                     MinE"
                     /protein_id="HHS5224485.1"
                     /translation="MLDLFRVFSNEAKTSKSVAKERLKLVLVHDRVDCSPQLLEMIKT
                     DILKVIANYAEIEDDGLEIKMSKCRGEHDDKPVSALVANIPLKNIKDRCM"
     gene            complement(24932..25729)
                     /gene="minD"
                     /locus_tag="KRH23_001197"
     CDS             complement(24932..25729)
                     /gene="minD"
                     /locus_tag="KRH23_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0000918 - division septum site selection
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="septum site-determining protein MinD"
                     /protein_id="HHS5224486.1"
                     /translation="MSEVIVITSGKGGVGKTTTAANLGTALSLENKKTVVVDADIGLR
                     NLDVVMGLENRIVYDIVDVVEGTCRLKQALIKDKRFDNLYLLPAAQTRDKNAVSVEQM
                     IDLCEKLKESFEYIIIDCPAGIEQGFKNAVAGADRAIVVTNPEISAVRDADRIIGLLE
                     ANEIKEIRLVINRIRNDMVKRGDMMDKQDIIEILAIDLLGLVPDDESIIISTNKGEPA
                     ILDSKSLAGQAYKNIAKRILNEEVPLLDLEVEDGFFGRLKKMFSMAK"
     gene            complement(25753..26436)
                     /locus_tag="KRH23_001198"
     CDS             complement(25753..26436)
                     /locus_tag="KRH23_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000902 - cell morphogenesis [Evidence
                     IEA];
                     GO_process: GO:0000917 - division septum assembly
                     [Evidence IEA];
                     GO_process: GO:0051302 - regulation of cell division
                     [Evidence IEA];
                     GO_process: GO:1901891 - regulation of cell septum
                     assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="septum site-determining protein MinC"
                     /protein_id="HHS5224487.1"
                     /translation="MSLREICSQELVEFKGNKRGIIVNIKREAPFEEIQEKIINKLEA
                     YVGFFNGAKISKINSDCLTDMEILELKEGITSRFDVEFVEDQKIEENSNFPTKYVNTL
                     RSGENIEFEGDVVILNDMKPGSKVLSKSNTVVMGDINAGAKVVAGGNVFVMGKIEGFV
                     HAGAEGNEFAYVVAGNLNPKILQIADNIAEAPDDEENYENESEISPEIAFVSNGRIVI
                     ESYLSKLDK"
     gene            complement(26534..29512)
                     /locus_tag="KRH23_001199"
     CDS             complement(26534..29512)
                     /locus_tag="KRH23_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HHS5224488.1"
                     /translation="MEENKQVDRLKIIKIVMGVIFLAILVKIIYMTTFKYEYYNELAE
                     NKTYKKLAIEAPRGEIKDRYGRLLAGNKNLFTVQVSGNDINKKDANKHSRANEISLKL
                     INLLERNGEEYVDEFPIYVENGKYYYTYDRDIREYKSENGIPNDYNAKESFYYLVDKL
                     ISAGILSQEDKRLDATRLQAKLNENGYYPPILVSKWMFTAERDKRDWLASYKIKETKL
                     SAKEAFEKVRNSDALEIDKSLSDEDARKIMVVRDLIKSKGYSQYNPVTIAKDVGETTI
                     AQIEESAMDLVGVSIAVEPVRYYPNGSLASHMLGYVGKMPSTQIESYLQKGYETGDMV
                     GLAGVEKSNESRLRGTDGYKMVKVDALGRISKEIESKKPKSGDTVYLTLDKDLQEVSD
                     NALKQIIEVASKGGTFKSKFGDKPISAYAGKAQSAALIAIDVKNGEVLASSSYPNYDP
                     NKFAKGISTEDYKALQPKNPNDLLAGSPLLNLVTQGEFQPGSSFKMVTSMAALENGLD
                     PNFTINDPGVIMLGKKSFGDYVWNHGRGNHGMTNLYKAIQESCNIYMATIGTGKTWPD
                     GKSIGIDMNANKILEYAKLFGLDQNTGLQDEVEERAGKVPSTEDKLKSTQALLKSNLE
                     REMANDFVDITREKNPKEYEKRINEIVSWAAEKKTPGRVETMNRLKKMNVKEDRIEDV
                     ADLAVFSYFNFAKWSTADTFNLAIGQGENAYTPAQISRYVAAIANGGNLVELSVVDRA
                     VSSDYSSVKINDQKKVEKIPFKNPDNLKELTKGMKLVARQGTAKSAFADFPIDVAAKT
                     GTAEKSGKIPTDNEYEYLKSHMSSYNVNLNDAIKLADKMKAEKEKELSLAKEKEIKKK
                     LENKDLKDEERKKLEEELEDGVKVRLEDTDKVNSSYLRKAIKELNPKITDDQIDRFKQ
                     DYGSFTWTVAFAPADDPEIAVVCVIPQGDSSVFSLLPTREVIGTYMGLEPTNSKNDNK
                     TNDVNNSSDENINFESQINR"
     gene            complement(29524..30012)
                     /gene="mreD"
                     /locus_tag="KRH23_001200"
     CDS             complement(29524..30012)
                     /gene="mreD"
                     /locus_tag="KRH23_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HHS5224489.1"
                     /translation="MKKVLLCLLGIVLMTIENSITNYIDIFGISFNLVLIYVTIISLY
                     LDELEGGIIAAIIGLIKDITVGGIFGVNALILFIIAYAIGYMRDQLYKGSYIITFVLI
                     FIGSLIDSIVNIGTSSIIYQSYNISTLFVKGLLVAPIVNSLIGLVIYRLSKRAVLKLK
                     ED"
     gene            complement(30027..30920)
                     /gene="mreC"
                     /locus_tag="KRH23_001201"
     CDS             complement(30027..30920)
                     /gene="mreC"
                     /locus_tag="KRH23_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HHS5224490.1"
                     /translation="MALRFDKNKNEKKRINVKVIATGVVAITLIGIVGISIGKFSSGS
                     PVNLGVASDAITSVGKGINDGFSFIKNGFKDVANFKDNSKKVKKLEEENEKLKKNMIA
                     LNAKLDKTESLEELKKTLNFVQEEYKATSISASVVGKNDGNWYESFVIGAGKNSGVKK
                     ESIVMNGSGLVGIVYEVSNNYSKAISLLDSKASVSFKLAKDANAKGTITQNTTLDNKD
                     SYNSKGYLQGYMFDSSYNVIQGDIITTSGLGFFPDGIPIGEVEKVVDDKDKSLKYVVV
                     KPYVDFKNINDVVVIEPRNIG"
     gene            complement(30930..31991)
                     /locus_tag="KRH23_001202"
     CDS             complement(30930..31991)
                     /locus_tag="KRH23_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000902 - cell morphogenesis [Evidence
                     IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein"
                     /protein_id="HHS5224491.1"
                     /translation="MAKEKKKEKKGFFSFNKMTKDMGIDLGTANTLVYIKGQGIVVRE
                     PSVVAIRDDSKEVLAVGEEAKKMIGRTPGNIVAIRPMKDGVIADFDITQSMISYFIQK
                     AADKKGVVSPRIAICVPFGVTEVEKRAIEEAARQAGAKDAFLIEEPMAAAIGAGLKVE
                     EPEGNMVVDIGGGTSEIAVISLGGIVTAKSIRIGGDEFDESIVAYVKKEYNLMIGERT
                     AENVKINIGSTFKDDEEINMQIRGRDLISGLPKTIEICSTEVREALKEPVSSIVDAIK
                     STLERTPPELASDIMENGIMLTGGGALLRGLDKLITQETGMSVQIAETPLDCVALGTG
                     KSVEDQEIFEKVLMMNTKN"
     gene            complement(32061..32720)
                     /gene="radC"
                     /locus_tag="KRH23_001203"
     CDS             complement(32061..32720)
                     /gene="radC"
                     /locus_tag="KRH23_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RadC family protein"
                     /protein_id="HHS5224492.1"
                     /translation="MAPEERPREKMLVKGVKSLSNAELLAILLRTGNKNKNAIELANY
                     IINRDIQGIRHLEDMTIEELCNIDGIGLSKSTQIKAALELGSRVASFKPIKYKIRNPW
                     DIQRYYMDSLRYLKKEVFKAVLLNTKNEIISDVDVSIGTLSSSLVHPREVFKEAIRRS
                     ASKIIVMHNHPSGSVEPSREDKNITSRLIKCGEIIGIEIIDHIIIGDGLYFSFKENMI
                     I"
     gene            complement(32765..33349)
                     /locus_tag="KRH23_001204"
     CDS             complement(32765..33349)
                     /locus_tag="KRH23_001204"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0047429 - nucleoside triphosphate
                     diphosphatase activity [Evidence IEA];
                     GO_process: GO:0009117 - nucleotide metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009146 - purine nucleoside triphosphate
                     catabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Maf family protein"
                     /protein_id="HHS5224493.1"
                     /translation="MNIILASASPRRKEILENTNVRFDIIKNEIDEIILEGETPKHLV
                     MRLAFEKSMSVASEHNEDVVIGADTVVVLDNAILGKPKDESCARDMLKRLSGREHQVI
                     TGISLINLCEDKKVIDYVISNVKFKTLSEQDIEDYLKTNESFDKAGAYGIQGYGALLV
                     EEIRGDYFNIVGLPISRLGDLLKKYFSINLFYGV"
     gene            complement(33569..34540)
                     /locus_tag="KRH23_001205"
     CDS             complement(33569..34540)
                     /locus_tag="KRH23_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0022900 - electron transport chain
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RnfABCDGE type electron transport complex
                     subunit B"
                     /protein_id="HHS5224494.1"
                     /translation="MVILTAVLVLGIMGLIFGIVLDFASKKFAVEVDERVEAILGVLP
                     GANCGGCGFPGCGGLANAIVEGNAPVNGCPVGGADVGAKVGEIMGISAEAGEKQVAKV
                     ICKGTCSSAKDKYEYEGISDCRAANVLNSGAKMCKFGCLGLGTCKDACKFDAISIVDG
                     IAVIDEEKCVNCGKCKEVCPKGIIITKPESQEVVVECNSKEFGKAVKEKCTAGCIGCG
                     MCVKACKFDAIIFEDKIAKIDPNKCVGCMQCVAKCPTKVISGDITKKKKVTIDQELCV
                     GCTVCKKQCKFDAIEGELKEKHKVDADKCVGCHLCMEKCPKKAIKIL"
     gene            complement(34556..35131)
                     /gene="rsxA"
                     /locus_tag="KRH23_001206"
     CDS             complement(34556..35131)
                     /gene="rsxA"
                     /locus_tag="KRH23_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0022900 - electron transport chain
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxA"
                     /protein_id="HHS5224495.1"
                     /translation="MNLILLFLSIVLVNNVITSQFLGICPFLGVSKKVDTAVGMGVAV
                     TFVLTLASIITYFIQILLVKTGTGFLQTIAFILVIASIVQFVEMVIQKMSPSLYQALG
                     VYLPLITTNCAVLGIALVNVQKSYNLVETIINGFGAGAGFTLAIVIFAGIRERLELAD
                     IPEAFKGFPITLISAGLMSIAFLGFTGLIKL"
     gene            complement(35146..35739)
                     /locus_tag="KRH23_001207"
     CDS             complement(35146..35739)
                     /locus_tag="KRH23_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0022900 - electron transport chain
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RnfABCDGE type electron transport complex
                     subunit E"
                     /protein_id="HHS5224496.1"
                     /translation="MNLAKVFKNGLIDENPTFVQVIGMCPTLAVTTSAINGIGMGLST
                     AAVLICANLVISLIRKITPDKIRIPIFIVVIATFVTIVGMLLKAYVPALDKALGIYIP
                     LIVVNCLILARAESFAFKTGAMPSIVDGVGQGLGFTVALTIIGAVRELLGNGSLFGMT
                     LFGASFQPVLIFILPPGAFLTLGFLFAGFNKLRSKKA"
     gene            complement(35752..36321)
                     /locus_tag="KRH23_001208"
     CDS             complement(35752..36321)
                     /locus_tag="KRH23_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_process: GO:0022900 - electron transport chain
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RnfABCDGE type electron transport complex
                     subunit G"
                     /protein_id="HHS5224497.1"
                     /translation="MNSMVRLGGTLLAISAIAALALGATNQVTAPVIEQRNIQANNEL
                     RKAVLPEAKEFKEMKEDTYKGLGDGIIAEVYEGLDGSEVVGYTLKAKPSGYGGEIEVM
                     VGISSEGQVTGVDIGNMSETAGLGAKAKDDAFKGQYKGKTAEPLEVAKGSTTADNQIL
                     AISGATITSTAVTTGVNAAIDVFNSALNK"
     gene            complement(36321..37298)
                     /locus_tag="KRH23_001209"
     CDS             complement(36321..37298)
                     /locus_tag="KRH23_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0022900 - electron transport chain
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RnfABCDGE type electron transport complex
                     subunit D"
                     /protein_id="HHS5224498.1"
                     /translation="MENKLIVSSSPHVRSNEDTSYIMKQVIIALLPAAVAGVYFFRLN
                     ALSAMFFCILGTVGTEFLYQKFTKQKSTIGDFSAVVTGLLLAFNVPASLPWWMCLVGG
                     IFAILVVKMVFGGIGCNFVNPALAARAFLLASFPVAMTAWTQPGVNWIGKNLDAVTTA
                     TPLSFLKNGAAGLADLSSNGISLADMMIGNIGGCIGETSAILLLLGGVYLMYKGIINY
                     VIPVFYIATVFILTFLLGGFNITFAIYQLFAGGLMLGGFFMLTDYTTSPMTKKGQIIY
                     AVLAGLITTVIRMYGGYPEGVSYSILLVNCLAPLIDKFVRNRVFGEVAK"
     gene            complement(37321..38658)
                     /gene="rsxC"
                     /locus_tag="KRH23_001210"
     CDS             complement(37321..38658)
                     /gene="rsxC"
                     /locus_tag="KRH23_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxC"
                     /protein_id="HHS5224499.1"
                     /translation="MKLLTFKGGIHPPYRKEYSNTKALEKAQAPKIVYIPLQQHIGAP
                     AKPIVEVGDEVKFGQKIGEQQGFVSCNVHSSVSGKVIAIEQHEVPGGSAQCVVIENDF
                     KEELHESVQPKGQLEDLSKEDIVGIIKEAGIVGMGGATFPNHVKVSPPPDSKAEVVIL
                     NGAECEPYLTADHRLMVENPEDVVFGLRALMKVLDVKKGFIGIETNKPDAIEAIQNVA
                     KDYSEIEVVGLQVKYPQGAEKQLIYACTGKEVPSGGLPIAAGAVVDNVATAAQIAKSI
                     KTGMPLVERITTITGSCIKEPKNLITKVGTLVSEIIEQCGGFKEDKKIGKVIMGGPMM
                     GIAQYTTEIATNKGSSGILCLDEEESRTPDIQNCLRCGRCTDVCPSFLQPLFISAYSL
                     KDDYDTAEYHRAMDCIECGSCSFICPARRPLLQSIRSAKREIGAKRRKQAAQK"
     gene            complement(38874..39818)
                     /locus_tag="KRH23_001211"
     CDS             complement(38874..39818)
                     /locus_tag="KRH23_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224500.1"
                     /translation="MNRRKTIYRGFNNNRHKIDLRKYVITIACLCLIGYYSYTKIKDS
                     KILEYVSAKIPFLNNSSDITYKDISDELNSIKKGKKSKSQTNSDDKQETNPEKAVNNT
                     KEPEEVKLATIEGWDMYTIQVAAIDNNDDLKKIQTSLVNNDIPFSVMEKDGVKKIQTY
                     SSFDENDVRKQISSVRKVFPDAFLSHLDAPMLSLEYTSNYAYIESISKELNKLITNFK
                     EESSFWSNAENNVDMEKYNTILTNRKAISQNISKEAEKIDYSEMRLFKDNLIEYVKNV
                     NEKIDTASKAANEEKYSVSKSLLLSSMQEYSMFINSIK"
     gene            complement(39929..41203)
                     /locus_tag="KRH23_001212"
     CDS             complement(39929..41203)
                     /locus_tag="KRH23_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HHS5224501.1"
                     /translation="MKKAIAALGIGAVAVSVSSINASALEKGTVTASALNIRSGPSSD
                     CDKVAKLYKGKTVEILEKSNGWYKVRVSSSVVGWGSAKYISTSGSSEGTSSQNNSTSS
                     GTTISGNGKVNVSSRLNVRSGAGTNYSLVGKANNGDVVKLLEQSNGWYKIKLSNGVTG
                     WASSQYISKTSEDVGTNNSSNSNSTNNSDKKPSSEESIEGKNGKVTSAVSLNVRSGPG
                     TSYSIIGKLNGGDVVELKAKSNGWYKVKLSSGTIGWVSASYISETNEDTKEKPNSSSN
                     QNSQSNSNSKPSFTGNSDKSTAKGSTIVDFAYTLIGIPYQWGASGPDKFDCSGFTQYV
                     FKHSVGVSIPRVSREQANFGSAISMGNYAPGDLVYFDTDGDGTTNHVGIYVGNSKFIH
                     CSGTQTNPNKVKVDNLTSSYWSKVLLGARRFV"
     gene            complement(41335..41706)
                     /locus_tag="KRH23_001213"
     CDS             complement(41335..41706)
                     /locus_tag="KRH23_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HHS5224502.1"
                     /translation="MKFNFCHNNFNVTNLEKSLDFYKKALGLKEVKRKEAEDGSFILV
                     YLGDGITSHTLELTWLRDWDRPYNLGDNEFHLALEVEEFDEAKKLHKDLDCICFENES
                     MGIYFIADPDNYWIEILPKNH"
     gene            complement(41934..42533)
                     /locus_tag="KRH23_001214"
     CDS             complement(41934..42533)
                     /locus_tag="KRH23_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224503.1"
                     /translation="MESRGYKEDLKKMILDMAHKELESYVSQKGAKKYFEGNLDKIIN
                     NNIKKFNQSIGLNRVYLKMLKKCAYQESVTSISRTIKKEALFKSKKELFAFSEYLKLD
                     INKRLSYNQILRKISRYIYYNRSSYAQKYVVFKRGDEEYLLEPEKIKDELISSYRSKT
                     REDMRSIAKLLDIEVEDDYNAEDIRKKVINYIIKEKLKS"
     gene            complement(42734..42946)
                     /locus_tag="KRH23_001215"
     CDS             complement(42734..42946)
                     /locus_tag="KRH23_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy-metal-associated domain-containing
                     protein"
                     /protein_id="HHS5224504.1"
                     /translation="MKKKLLVEGMSCGHCVNHLKTALTEDIDGIEVLDVDLENKCASV
                     DMKDDVSIEKLKEVIAELGFELKGIE"
     gene            complement(43019..44734)
                     /locus_tag="KRH23_001216"
     CDS             complement(43019..44734)
                     /locus_tag="KRH23_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HHS5224505.1"
                     /translation="MKRIKVLTVVLAITLMVAGCSNTKTKQSSSDSSLQSQSSIDAKY
                     INLTMVTPKTINPITNTDKSVGYIMNLVYDSLFTIDENYNVIPQLVKEYNIAQDGMSI
                     DIKLKDAKWHDGKNVTSNDVNYTIGLIQKSADSPYNEFTKNIASVNIKSDKDFTIKFK
                     ARYAFSIDSLIFPIVSQNHLDSKDVNDKNNNMIGNGKYKIESYTEREGMVLSVNKDYY
                     EEVPKTMKNIKVGMVPNEDARTSMVMALDSDITNVTLNDLSKFQEKEFNITKYQGRDY
                     ECVLFNYNNPFFKDVNFRKAIAHSIDKDRIISEGYMDDATPVNFPLNSKSKYYNSEMK
                     DLEFNKDKAIECLAKVEYANVNSVNQNDNKVKNQKKSAKKNSKKLTPEEEAKAKKAEE
                     DRIKKEAEEKKNREKEEVKKSLSEMNLKIIVNRDNSERIKTANIINENLKAIGINSTV
                     NQLSDKDMENALNSKNYDLALVGWKLSIIPDASSIIASSGYTDDKLNGYMSALTSSTS
                     EIETKKAYKDVQTYIKDNATFISLAVRNNYIVSNSRLKGKITPNDFDVYEGISNLDIK
                     SNESN"
     gene            complement(44734..45288)
                     /locus_tag="KRH23_001217"
     CDS             complement(44734..45288)
                     /locus_tag="KRH23_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing
                     protein"
                     /protein_id="HHS5224506.1"
                     /translation="MNSKKVLILSIFIILFGALLMESKVIHKFLYPKKYSEYVEKYSK
                     EFNLDENIVYSVIKAESKFNSSAVSKKEAKGLMQILDITRDWGAEELNLKNVDIFDPE
                     TNIRLGCWYLSKLYKEFGKLDLVIAAYNGGSGNVKKWLENNEYSKDGENLHDIPFKQT
                     SKYVEKVKNNYEHYNKIYGKKGKN"
     gene            complement(45281..45883)
                     /gene="coaE"
                     /locus_tag="KRH23_001218"
     CDS             complement(45281..45883)
                     /gene="coaE"
                     /locus_tag="KRH23_001218"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419019.1"
                     /note="Dephospho-CoA kinase (CoaE) performs the final step
                     in coenzyme A biosynthesis; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004140 - dephospho-CoA kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HHS5224507.1"
                     /translation="MLILGLTGGIGCGKSSLSNIFRNLNIPIVDADIISRKIFEDKLL
                     LEKVFVHFGQSIKNDDGTLNRKALGKIVFSDEEKLKELNNLTHPRIREKIISEIEKLR
                     KKGENIVVLDAAILVESGFLDMVDKLLVVTCKQEVQISRIQKRDNCSEQEALSRINSQ
                     MSQEEKSKYGDYIIDNSGTITELESKAHKFIEYMKENWRE"
     gene            complement(45892..48540)
                     /gene="polA"
                     /locus_tag="KRH23_001219"
     CDS             complement(45892..48540)
                     /gene="polA"
                     /locus_tag="KRH23_001219"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006261 - DNA-templated DNA replication
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HHS5224508.1"
                     /translation="MEKKLIIIDGNSIINRAFYALPEMNNKEGLKTNAIYGFTTMLFK
                     MIDIYKPTHISVAFDRKAPTFRHLEYKDYKAGRKGMPDELAEQLQPLKDLLDKFKINR
                     LEIDGYEADDIIGTVSKKAEENGYKVYIVTGDKDAIQLASDNTTTLITKKGVGEVEEY
                     NFNSVIEKYEMTPTQFIDLKGLMGDKSDNIPGVPGIGEKTGIKLIKEFSSIENLIENT
                     DKLKGSVKKKIEENKEIAIQSKRLATIIRDVPIEVDLDSMIFGDYDKDELLDKFRYFG
                     FTSLLSRLVDLVDSDDTEHIEEKIEILKLKDTEKFIDEVNKKGQVILKTVRGQGNILE
                     KNIIYIFISVDGEKIYYVDSNEVSKLDSIFSNNEIKKYGYNLKDDYISLKPYNINLEN
                     MYFDITIAEYLIDSTSSTSYDCSAIAMKYLSKKVKSKEELLGKGVKSKNYEDLEFEDL
                     AEYMGQIICTVKETVPMMERSLMDMSMDGLFYHVEMPLVEVLGHMEYEGIKVDKSILD
                     ELSVEFKEIIATLEKEIYELSGEPFNINSPKQLGVILFEKLELPIIKKTKTGYSTNAD
                     VLEKLRDKHPIIDKITEYRQIVKLNSTYVEGLLNIINPESNRIHSSFNQTITTTGRIS
                     STEPNLQNIPIKMEMGRKIRKVFIADDNCKLVDADYSQVELRVLAHMSQDENMIEAFK
                     HHEDIHTKTASQVFNVPMEDVTSELRGAAKAVNFGIIYGKSDFGLADDLNIPVPKAKE
                     YIESYFAKYHKIKEFMDTTVEKASEDGYAVTILNRRRYIPEIKSSNFMERNRGKRFAM
                     NAPIQGSAADIIKIAMINVHKKLEENNLKSKLILQVHDELIVEAIDDEIDIVKKIVKE
                     EMENAVNMDVHLDVDLNVGSSWYETK"
     gene            48692..48779
                     /locus_tag="KRH23_001220"
     tRNA            48692..48779
                     /locus_tag="KRH23_001220"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:48726..48728,aa:Leu,seq:caa)
     gene            complement(48966..49409)
                     /locus_tag="KRH23_001221"
     CDS             complement(48966..49409)
                     /locus_tag="KRH23_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224509.1"
                     /translation="MKKNMLYVGIIYFICGILLVLLATFTEFSFEAFIWGLSGAALGP
                     GVCMILQYMYWSKPERAVDYEEKIKNQRIEMNDERRIMLRDKAGRITNQIMCYVLVIL
                     IFIVSILSVFSVMVISKWVLVVLGLLILFQFICSVVVYNKLDKRL"
     gene            complement(49412..49609)
                     /locus_tag="KRH23_001222"
     CDS             complement(49412..49609)
                     /locus_tag="KRH23_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004631111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HHS5224510.1"
                     /translation="MKNRLEEIRKERGIKQEELASILQVSRQTIGSLENGRYNPSIIL
                     AFKIARYFDMSIEEIFIYEEE"
     gene            complement(49801..50667)
                     /locus_tag="KRH23_001223"
     CDS             complement(49801..50667)
                     /locus_tag="KRH23_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HHS5224511.1"
                     /translation="MEWINKLNQAITYIEENLESGVDYAEAAKIACCSTFHFQRMFSY
                     IAEVPLSEYIRRRRMTKAAFELQNSNIKILELSEKYGYDSPTSFNRAFQNIHNISPSA
                     ARAKGVVLKAYPKMTLSIYVKGNIEMQYRIVEKKGFRIVGIKESMNMIVEECFEKVPK
                     LWAKCIKNGTIDKLSELINNEPCGLLGVSVCTNSKGLDYYIAAPTDKPVLEDTHEYLI
                     PSGTWAVFECVSPMPNALAIQELQKRIITEWLPSSGYVYANLPDIELYPNGDINAPDY
                     TTEVWIPIQKPS"
     gene            complement(50893..51762)
                     /locus_tag="KRH23_001224"
     CDS             complement(50893..51762)
                     /locus_tag="KRH23_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HHS5224512.1"
                     /translation="MDYKTIILNRKSVREYKNTDIKEEYLSEIKKYSESCKKLVPEID
                     VDVRIMNRSEVFNNLDKVAGYKGNMIDSPSYIIILSDIKDNYIENSGYIGESIIFKVT
                     ELGIGSCWVTFEDGKKVKEKLGINSDKEVTGIIAIGYGENVSNAKVLNATKTGQNYSK
                     SDMQVVTDKGSTRLGVEDVVYMNEWGNVASIEILEERALLDAFHYARLAPSTLNRQPW
                     RFIVDGGTVVLAVRKDGHTNLYEEKIDIGIVMLYFATIISATMFDLKWNLGTPDKDYK
                     VPEDYKIVGYCNI"
     gene            complement(52268..52489)
                     /locus_tag="KRH23_001225"
     CDS             complement(52268..52489)
                     /locus_tag="KRH23_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224513.1"
                     /translation="MNVNNHKCPECGEHSKKFEIVEENEDCVIFECYTCGTISILKYC
                     ENCKEFVFVNIPNNVETYEYCCGKCNNKI"
     gene            complement(52990..53970)
                     /locus_tag="KRH23_001226"
     CDS             complement(52990..53970)
                     /locus_tag="KRH23_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224514.1"
                     /translation="MGDTSRFYESVKNKYPKLKDGTRVHLWPKENIIIGPIYDEEDGY
                     KKSIGNVDSLSWKQIVILAECDGKNTTDDIINILSNRYRNIHNMKEKVMEFFMFYENV
                     YLTFEDDIQTLSSVFEITGNKSYITPLYFTIEIDGDNNTNDYFSEITSLLNCMYEKGC
                     RFIEVIGEDILKNKSMREIFQYMLDHFDLIVVTKDSFTIDRSLIKELDNYRHKVIWKV
                     YSKNDDTRIKLKEDIKITSLIKRGHTVVRGDREKAIKIEDMRFKDTKERFSKYGAEWS
                     HLYISSDGSVKSYSFQKDKRIYLGNIFNNSVEEIFLEMQNKIDKLEIVYQ"
     gene            complement(54134..55006)
                     /locus_tag="KRH23_001227"
     CDS             complement(54134..55006)
                     /locus_tag="KRH23_001227"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0016311 - dephosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HHS5224515.1"
                     /translation="MIIKVSMTVLVLILLYILYKYETQHIETTEYTIFNKKIPKEFDN
                     FKIVQVSDLHNKVFDKNNKVLIDKIESLNPDVIFITGDLVDGENKNFQVALDLIDNLV
                     EKYEVYHIIGNHEQKSLIKKYKHLYKDYFKELYSKKIINMENESVRIYRGNSHLNLYG
                     LIIPLECYPYLFANNKKLELSDNFVEDNLGKVNENEYNILLAHTPFFFEKYAKWGADL
                     VLAGHVHGGIIRIPFVGGVLSPNREFFPKYDWGKYEKDNSTMILNKGLGGSKVLIRLN
                     CKPEIVKITLKYEK"
     gene            complement(55170..55721)
                     /locus_tag="KRH23_001228"
     CDS             complement(55170..55721)
                     /locus_tag="KRH23_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHS5224516.1"
                     /translation="MDNKFPNVGENLRLLRQEMGISLDKASKMTGVSKAMLGQIERGE
                     SSPTVSTLWKISSGFKINFTTLLNENTNTYEVIKKEEVEPIVEQKGNMKLYPIYPFSP
                     QRRFELFIIELEENCTHVSSTHSHVLEEYVLVIEGKLDLNVDGKTYILESGHSIRFDG
                     TLEHIYKNLNKGKTIFHNIEVYR"
     gene            complement(55741..56643)
                     /locus_tag="KRH23_001229"
     CDS             complement(55741..56643)
                     /locus_tag="KRH23_001229"
                     /EC_number="1.97.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0043687 - post-translational protein
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HHS5224517.1"
                     /translation="MSKKGRVVKVQHFSVNDGDGIRTTIFLEGCKLKCKWCSNPDSWS
                     NIVKLGVMKDKCVSCNRCIDVCPQNISSLFDRTQINNKCDLCGECIKVCLKDAICIMT
                     EEMSVEEIVEEVEKDFIFFFESNGGITFSGGEPTLQIDFLRELVDIFYDKGINIAIET
                     CGYFDWNKVNDVFEKIDHIFVDIKSMDDNIHKEYTGVSNKIILDNICRLSKLNKSMVI
                     RVPIIYGVNDSEENIRNTALFVKQNVPGGKMELLPYHKFGIDKYKALGLEDYIYEFDE
                     ICNNHMLKLKEIVELTGVKIIEYK"
     gene            complement(56658..59030)
                     /locus_tag="KRH23_001230"
     CDS             complement(56658..59030)
                     /locus_tag="KRH23_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HHS5224518.1"
                     /translation="MSQTNRIEAFRQEYINSKPMICCERARIFTESHKKTEGEAICIR
                     RAKAFLETCKELPIKIFENELIVGTAGKFRRTGILTPEFSWQWVDKEMDTFDKRTQDP
                     YVISKEQIEFIRKEIFPYWKGKSLEEVFLARIPEDTAKILVDTGIIDNDSKWRQAVGE
                     VTPDYQDILFVKGYKGIKEDADKKIKELDISVSENIEKIDFYKSVSIVAQGIMTLAQR
                     YSNLAKEMSKQETDEKRKLELIKISEICMNVPANPPTNFYEAIQFVWFVQLGGILSEN
                     PLALNLGRFDQYMYPYYENDAREGKITESEAQELIEALWIKLSEWVWTISANTANYFA
                     GYNQFQNLTVGGKKRNGTDGTNDISYMCLKATESVKTHQPGLSVRVSQGAPDNFVMAV
                     AKLVKQGTGFPAIHSDSAGAQMLLQDGYDAEDARDWSNCGCVVPHFRKTGQWTSAVNI
                     NFAAALEYAMNEGKSRLTGEKMGLDTKNITEFTSFEELKDEFLKQLAYLVKSSVIGTT
                     VAQQIHKEMVPRPFLSTCVDGCLDKGVDLSKGGAKYNIGPVLTGIGLGVVSNSLAAIK
                     KLVFEDKVTTLEELTKALNNDWEGYEELRKLALDVPKYGNDNDYVDSLAIEVSDFYYT
                     ETRKYKDIFGSKFNSAFMGISNYVPTGKIVGATPCGRKATKPLTEGVSPFVGTDTTSP
                     LAAMKSASKINHDVHTGGTLLNLRLNQDLVETERGLRNLTSMIKSYFALGGFHVQFNT
                     ISNDTLLKAQENPEEYKDLLVRVAGYSTQFVNLSREMQDAIIARNSHSNF"
     gene            complement(59251..59940)
                     /locus_tag="KRH23_001231"
     CDS             complement(59251..59940)
                     /locus_tag="KRH23_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224519.1"
                     /translation="MKVKRNINRVAIIVALNLSLALMVGCMSPVSDKNLSSSEQISKD
                     SLKEQVEDKKDESIELFNNYSQKINDAKGREEVKKDLSQRFSKAIIDSGYSITDSKSD
                     GSFVVSINGAEKPPEKNIRSLFYSMSEDDKEGKVTIDILCAKEYPEDDKLSESDKYIK
                     FIYNLFKSLTNTNLTEKEIFSMVEEEFNKGVGVVELPYMKDIHVEVNKVKQSTKVLKL
                     SLVYKFDISNH"
     gene            complement(60181..61302)
                     /locus_tag="KRH23_001232"
     CDS             complement(60181..61302)
                     /locus_tag="KRH23_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HHS5224520.1"
                     /translation="MGYIKYSIFFYLFSVYYKCLDAVIYRILFFAITGNVISSKESLL
                     VPYLESIKIQIYSNLIIILIYLIFRFFRKSIKLISQDKRNYVYLLFALLVNTMNMLVN
                     YVLKKLERFGSLHSEGYYFDNFVNPKLVGASSIFLILLFKEIIKENRLKSQAELIKNK
                     LDMQYAHYLSIQESHMRVKKLYHDINNHIYCIDNLRNNSKEINEYVNNLKDEIKTFKY
                     IYNTGNMILDIIINEKSEVCLKKGIKFTCSINFSKVNFVKPIDVSSIFSNILDNAIEA
                     CDKIVDENVNKYIRIKGTITRSFFVLKCENSKLNQLTFNKNILLTNKMDKFVHGIGIQ
                     SIKSSLQKYNGELLFENSIDKFILNIYIPLDQDTDSWGD"
     gene            complement(61554..62267)
                     /gene="rgbR"
                     /locus_tag="KRH23_001233"
     CDS             complement(61554..62267)
                     /gene="rgbR"
                     /locus_tag="KRH23_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RgbR"
                     /protein_id="HHS5224521.1"
                     /translation="MIKIAVCEDEKETQLLIEDYLENILKDISIEYEIQKYISGEELL
                     ESNLKDIDILLLDIKMEKLNGMDTARKIREVDNEMEIIFVTSLIDYVQEGYEVRAYRY
                     LLKPIELEELKKHVLTCIKDIEINKESHITIKNKSNTYKIYLNEIKYIEVQKKDMLIH
                     TINKNFDIKYSLGKIEKELNPYKFIRCHKSFIVNLRYVENIKPNTAILESGEEVPISR
                     YRYKEVKEKFLKFLGDTIC"
     gene            complement(62518..63069)
                     /locus_tag="KRH23_001234"
     CDS             complement(62518..63069)
                     /locus_tag="KRH23_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
                     /protein_id="HHS5224522.1"
                     /translation="MEKKIKFKFDWYSSPDKIEKWLEDIEAKGYNLYKINKFGGIFYF
                     HKGSPRKIKYTVDYYYDVENNYFDEHKSNGWNLVFRSIGSFMGTSAWYIWSKEYKDIP
                     PKLYSDSDKKNKVKSILFMNMFIFFMLVVIFIYLLNIEIRNLYSGYGASVTAIVLQII
                     LLILYAVQLYRRLMYYLRLKKFK"
     gene            complement(63174..63977)
                     /gene="zupT"
                     /locus_tag="KRH23_001235"
     CDS             complement(63174..63977)
                     /gene="zupT"
                     /locus_tag="KRH23_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc transporter ZupT"
                     /protein_id="HHS5224523.1"
                     /translation="MNNVIFAFLITLLAGLSTGIGSCIAFFAKKTNTKFLSISLGFSA
                     GVMIYVSMIEIFPKAQDALTKSMGEKLGSWSTVIAFFIGMAIIAVIDKLIPQEENPHE
                     IKKMENIEEKNIKKNKSLLRTGIFTAMAIAIHNFPEGLATFISALDDVTIAIPIAIAI
                     AIHNIPEGISVSVPVYYATGDKKKAFYYSFLSGMSEPLGAIIGYVLLRNFLNDITLGI
                     VFAIVGGIMVFISLDELLPSAREYGEHHLSIYGLIAGMGVMAISLLLFK"
     gene            complement(64128..65291)
                     /locus_tag="KRH23_001236"
     CDS             complement(64128..65291)
                     /locus_tag="KRH23_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HHS5224524.1"
                     /translation="MDIKEITKSYKDYVIKLRREFHENPEKSMEEVRTSKRVKEELDK
                     IGIPYVSAGGTGVIATIKGANPGKTVALRGDMDALQVVECTDVEYKSKNEGLMHACGH
                     DGHTSMLLGAAKVLNDIKDSINGTVKLFFQPGEEVGKGARAMIQDGAMEGVDSVFGIH
                     LWTDVESGTISVEEGPRMASADFFKITVKGRGGHGSLPHQGVDAVLASSAIVMNLQSM
                     VSREVSPLEPLVVSVGVLNSGTRFNVIASEAVLEGTIRLFNPELRKQIPGILERIAKS
                     TAEAYRADAELEYGYLTPAVINDKECSKIATDAAIKLFGEDCITLFEKVTGAEDLAEF
                     MNIAPGALAFVGARNESKGACYPHHHGCFNIDEDALEIGTALYVQYAVDFLNK"
     gene            complement(65351..66538)
                     /locus_tag="KRH23_001237"
     CDS             complement(65351..66538)
                     /locus_tag="KRH23_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224525.1"
                     /translation="MEAITAFCLVLVSLTIGDIVSAKTKAFVPSVFVSAIIFIVGFWT
                     FFPENIVDLAALGTPLAQLGMLLLITHMGTMMSIKELAGQWKTIVIALAGIVGICVGA
                     LALGTVVFGWDTAVIATPPLTGGLVASIMMADAATAKGLASLSVLAILMYVAQGFAGY
                     PITALMLKKEGKRLLSDFRSGKVTVNTDEEKVKDLPEQKSRFKIIPDLPEKYDTTYMI
                     ILRLGFVAWLAVQFTNLTNEVVSRYVICLIFGVIASELGIVDRKPLNKSGSFGWLMTS
                     LMAFIFAGLAKATPAMLVEMAVPLVGIIIFGVIGMGIFSIIVGKLLGESKEMAFSVSL
                     TSLYGFPPNYILTEEAVKALAETPEEKEFLMDKMLPKMLVGGFTTVTIASVVIAGIFV
                     NLI"
     gene            complement(66901..68601)
                     /locus_tag="KRH23_001238"
     CDS             complement(66901..68601)
                     /locus_tag="KRH23_001238"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHS5224526.1"
                     /translation="MIKQFVKYYKPYKKIFTLDLIAAFLFSLCDLVYPMITRNIMDDV
                     VPNKNLRMLVVFAVALILIFIAKAGLNYFMQYWGHVIGVDMQADMRNEVFTHLQRLPN
                     TYFDNNKSGVTMSRIVNDLMDITELAHHGPEDLFISIVMLVGSFFILIDINIPLTLII
                     FAILPFIIWFAIAKKDKMNIAFMKSRVTIGDVNATLENSIAGMKVTKSFCTEKEELNK
                     FVRSNKLFRRARQDSYKVMAEYYSGMNLYMDILEWVVVIAGGYFTYIGKITLGDFAAY
                     ILYVKMFIQPMKKLINFTEQYQNGMTGFKRFIEIMEQDHQKEAKNPIELENVKGDIEI
                     ENISFTYEDKTQVLDNLSLSIKAGKTIALVGPSGGGKTTLCNLLPRFYEFDKGDIKID
                     GKSIKDVSLKSLRKNIGIVQQDVFLFTGTIRDNILCGNPNATDEEMIAAAKKARIHDF
                     VETLPDGYDTYIGERGVKLSGGQKQRISISRIFLKNPPIIILDEATSALDNVTEREIQ
                     ESLEELSKDRTNLVVAHRLTTIKNADEIIVLTDKGIEERGTHEELVNKNGVYSRLHNN
                     "
     gene            complement(68844..69119)
                     /locus_tag="KRH23_001239"
     CDS             complement(68844..69119)
                     /locus_tag="KRH23_001239"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HHS5224527.1"
                     /translation="MKKILVACGAGIATSTIVCDRVERLVKENNIQAEVEQCKIAECS
                     TKQEGADLIVSTTILPTTYDIPTIKATGYITGINTTALDKKILNALK"
     gene            complement(69238..69789)
                     /gene="mobB"
                     /locus_tag="KRH23_001240"
     CDS             complement(69238..69789)
                     /gene="mobB"
                     /locus_tag="KRH23_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006777 - Mo-molybdopterin cofactor
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-guanine dinucleotide biosynthesis
                     protein B"
                     /protein_id="HHS5224528.1"
                     /translation="MKGHNFMYNILSVVSYSGVGKTTLIEGIIKELNKKGYRVGVIKH
                     TCHDFDMDEEGKDTYKHRKSGARKVCIISDKRVAYIEELKEKNPLYKMIQLYEDMDLI
                     IIEGYKNYRFKRLEVTRKGKYEDILSNKSDLIGIVSDIEYKLNIEQFNLNDYKNISKY
                     IESCIKNEILSISNVEIKNILKE"
     gene            complement(69794..70975)
                     /locus_tag="KRH23_001241"
     CDS             complement(69794..70975)
                     /locus_tag="KRH23_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030151 - molybdenum ion binding [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin molybdotransferase MoeA"
                     /protein_id="HHS5224529.1"
                     /translation="MIELEDAIKIIEKNVLPINRVKIVNLIDAVNKVVAEDIYSTIDS
                     PPFDRSPYDGYAYNANSENRNLKVIGTLYAGDVFNRVLNKNEAVKIMTGGKIPQGANC
                     VIKKEDVTVIGDMITLNIKLKEYDNYIFKGEDIKKGQLIINKNQNIGYDGIGVLASLG
                     ISKVTVYDDLKVGILNTGTELQDINETLENGKIYDSNRYTLYSRLLKLGIQADTICNC
                     SDDILELEKKVKNMLQSVDFLITTGGVSVGDKDLIPDVFKKIGATELFWNINIKPGGA
                     CYVGTLGEKLLFGLSGNPHAAIVVFDNVIVPVIEYLTYKKGTHHIKAIFKGEFNKLSN
                     KDRFVSGKLYTSEGKLYVELNDKKDAKARLSATLRSNCMIKIKKNETIKENQLVDVVI
                     R"
     gene            complement(71186..71920)
                     /locus_tag="KRH23_001242"
     CDS             complement(71186..71920)
                     /locus_tag="KRH23_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224530.1"
                     /translation="MKLKRSLVCVTILGIILVGCHKENTKEKNQVASKATQQKTMTKV
                     QNDVNEIMNKDYKYIIKNMGIPYNTFYYIKPKVLKESNTMQDINTSSYMTLVYPKYTG
                     NDELDGSALYVDINENKVVNVETNSFSSQGISVIDAESSIVIEKSDHEKSAVSLENFR
                     HIDLGEYVGVEDSRINEIVGDANYDLTAYNHEGSKVVKSYRLKEDNKILKKEVLTISI
                     VDNKIKSIKTIESDKIVKIIKGTLLE"
     gene            72282..73187
                     /locus_tag="KRH23_001243"
     CDS             72282..73187
                     /locus_tag="KRH23_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="selenium metabolism-associated LysR family
                     transcriptional regulator"
                     /protein_id="HHS5224531.1"
                     /translation="MDFKQLEVFVAVAKHQSFSKAARELFLTQPTVSAHIQNLERELE
                     TVLINRSNKVITLTKSGEILYEHAIYILNNCKRAIYDIKEYSGKIEGIIDIACSSIPE
                     TYILPDFMKSFSMSYPDVKFSISHYDSQYAISEILNERISFGLVGSKINNPQIEYLDL
                     LDDELVLITPSDLKIDNKNNCIDIGELAYLNFIMRKEGSGTRNLILNTLSKNNFPVSK
                     LNVIAHVESNEAIKEMVRLGLGVSFISYISAIDYLNAGKIKCYKIKDVDFTRKFFFIY
                     SKKKTFSPLEDKFLNRLCEYFEIII"
     gene            complement(73347..74189)
                     /locus_tag="KRH23_001244"
     CDS             complement(73347..74189)
                     /locus_tag="KRH23_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HHS5224532.1"
                     /translation="MTTSSKKLETISPDSKITRKDFWKCFRRSLTLDSSWNYERMQNI
                     AYAYMMAPIIRRLYKDDKEKKSKALKRHLEFMSVTPHISTLLVGISGAMEEENAKNKE
                     FDANSINAVKSSLMGPVSGIGDSFFWGTLKLIAAGVGIALASQGNIMGPILFLLIINV
                     PHFIIRYICLDKGFKYGTQFFKDVSGSSIVSKVMEAASMLGLMVIGGMTASNVMLKLS
                     VNVGSGEWAEPIQTYLDQIMPCMLPAMIFGIMYWLLGKKVKTTTILISVMIICIVLAA
                     IGVV"
     gene            complement(74173..74931)
                     /locus_tag="KRH23_001245"
     CDS             complement(74173..74931)
                     /locus_tag="KRH23_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HHS5224533.1"
                     /translation="MEFTQVILITLIAFFAYMHSFVGSTMHNRPIVVAPLVGLALGNL
                     HTGIVIGSTLELVFMGAFPVGASNPPDFVSGSIIATAFVILTGQDVSAAVVLAVPIAT
                     LVLLIDNFLMTVVLTWGAHIADRYAEEGNIEGVERVQLLFGIGNKLILAIIVGIGFSL
                     GVPVIEKILSFIPSYVTHGMDVAAGVIPAIGFAMLARMMLNKKTVAFLLLGFILVAYL
                     NITVTGVALFGLAIALIYVNFVGEKEVIVDDNEF"
     gene            complement(74948..75418)
                     /locus_tag="KRH23_001246"
     CDS             complement(74948..75418)
                     /locus_tag="KRH23_001246"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HHS5224534.1"
                     /translation="MIKLVRVDHRLIHGQVAFTWTKFLSTDCILIASDDLLKDELRMA
                     GLKMAKPSNVKLVMKSIADSIKALNSGVTDKYNLLILCESVEDVYRLAKEVKAIKSIN
                     LGGTKSDDNRENISKAVHVSKDDIKMIKELDSEGVNVFVQLVPDDDATNVMKLI"
     gene            complement(75418..76161)
                     /locus_tag="KRH23_001247"
     CDS             complement(75418..76161)
                     /locus_tag="KRH23_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BtpA/SgcQ family protein"
                     /protein_id="HHS5224535.1"
                     /translation="MKKKGILSVFKSKKPIIAMIHLKGDTPEDIFERAKKEITIFEEN
                     GVDGIMLENYYGNYYDLERILEYVSKANLSIPYGVNCLNVDTMGFELATKYNASYIQV
                     DSVVGHVKPRDEATLEEFFKLQRSKCPAYLIGGVRFKYQPVLSENDVEEDLKIGMTRC
                     DAIAVTENATGQETSMEKIELFRKNLGDFPLVIAAGVTLENAKKQLKLGDMAIIGSYF
                     KDNYKDFGDVSVEHVKTFMDEIKKIREEL"
     gene            complement(76165..76578)
                     /locus_tag="KRH23_001248"
     CDS             complement(76165..76578)
                     /locus_tag="KRH23_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HHS5224536.1"
                     /translation="MKKIILASHGDFSKGLLNAVKMIVGDLADCVSSYGLYPGQSASD
                     FALELEKTISEDKECEYIILSDLYGASVCTAMLRLTNLHNVRLFSGMNLNMVLELLTR
                     FSDELTVEDIDQLVEESRRGIQSVTLQIKEEEEVF"
     gene            complement(76604..77179)
                     /locus_tag="KRH23_001249"
     CDS             complement(76604..77179)
                     /locus_tag="KRH23_001249"
                     /inference="COORDINATES: protein motif:HMM:NF019322.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HHS5224537.1"
                     /translation="MRNALNELVKEDILCKKRGKGTYVTIPERIEATCAGNSFTNSCH
                     RINAKPSTKIISVLIKKADKQVAEALSIELEEKVICIKRLRLIDEVPVIFEVDYFRID
                     YMFLLKEELEDKSLMEVISNNISTLPKRVENIFEVKHSNKEYSDHLKCASNMPLLKVR
                     QSVYTENNDVLYYNEQFIRSDKYKYAVSAEI"
     gene            complement(77373..77756)
                     /locus_tag="KRH23_001250"
     CDS             complement(77373..77756)
                     /locus_tag="KRH23_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HHS5224538.1"
                     /translation="MKISKLPEAELKVMRYIWEANDVLTSKELVAAMEEKYEWNESTT
                     FTVLKRLERREFLSTEKIGKLTHYNAMVKEKKYLRFETKEFLKNIHKNSISSLISALH
                     SKDDEVDEDKLIELEEHFKNLKEKE"
     gene            complement(77866..78243)
                     /locus_tag="KRH23_001251"
     CDS             complement(77866..78243)
                     /locus_tag="KRH23_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HHS5224539.1"
                     /translation="MKEEILVEKLLRAELIVMEYLWKKDSLVTKKEIVKEMRQVYGWH
                     KSTIKILLKRLVDKGYLARDIIKFQSHYKIIIDNKEYYAFKKKVLKSSKSRKIMRSLT
                     TTHKSISKEKLDALEEYYRNLEE"
     gene            complement(78750..78893)
                     /locus_tag="KRH23_001252"
     CDS             complement(78750..78893)
                     /locus_tag="KRH23_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA];
                     GO_function: GO:0090729 - toxin activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin"
                     /protein_id="HHS5224540.1"
                     /translation="MSEFLLGVLASLTASFITYIISRKVKSHSGRSDFELDVKIKFNK
                     KRH"
BASE COUNT        25104 a        14400 c         8377 g        31153 t
ORIGIN      
        1 taacatttct acatttttat aaattttttt acgtttttta attttataat taaaaattta
       61 aattttatac atattataat aaattgtgat atatataaaa taattaaaga taaaaggagt
      121 attttatgaa catacttgga ttaatagttg aatataaccc atttcataat ggacacatat
      181 atcatttatc taaatctata gaaaaaacaa atgcaacaca tactgtagca ataatgagtg
      241 gaaattttct acaaagaggc gaaccagctt tatttgataa atacactaga gcaaaaattg
      301 ctgtcgaaaa tggtgtagac ttagttatag aattaccaac tttatttgct tgtcaaagtg
      361 ctgaaatttt ttctcatggt gctataacaa ttttaaattc actaaactgc ataaattcta
      421 tatgttttgg tagtgaagaa ggaaatacag aaattcttta taatatagct gaaattttag
      481 caaatgaacc aaatgaattt aagttacttt taaaaaaata tttagatgat ggtctgttat
      541 ttccaacagc tagagctaat gcactttttg attatataca tcaagacaaa aaaaataatt
      601 ttatacaaaa ttattcaaag gaacaattat caaaaacatt aaattcatca aacaacatac
      661 tgggtataga atacataaaa aacctcatcc atttaaacag tagtataaaa ccatttacta
      721 tctccagggt ccaatcagaa tataattccg aagaaattga gagtgatatt tgttctgcta
      781 ctgctataag aacttcactt aaagaaaata cagacctttt tcatttaaaa aatgttattc
      841 cagaaaaaac ttataacatc ctaaatgaaa aaatagataa tggtttttta cctatgtttg
      901 atgacttctt ctttgatatt ttaaaaacaa ttatacttag agatatggac actttaaaag
      961 agtattttga agtaaatgaa ggtatagaaa acagaatcta taaagatatc tttacatctg
     1021 aatttctaca tgaactacaa ttagcaatta aatccaagcg atacacttta accaaaatca
     1081 aaagaactct aaacaatata ttgctaggta ttaaaaaaag cgacatgcaa cttataaaaa
     1141 acatagatac tataccttat ataagaatgc ttgcttttaa tgataaaggt agagaaattc
     1201 taaaagagat aaaaaataaa tctgaaataa aaataataaa caagttttca aatatatcat
     1261 tttcattaga tgatacgatt tttaaaacac tcataagtta tgatataaaa gctacaaata
     1321 tatataattc aatatattat aaaaacaata aagatttagt aaaaggccct atggattttt
     1381 atactcatcc aatatatgta aagtagtttt ttaaaataac tatatttata aaaatcattt
     1441 tattaactct ttattatata agatacaata gtcttacttt atttatgtac acatgctttt
     1501 aggatgacaa catcaactta aatattatgt tactttctaa atttaagtaa atattgccat
     1561 cctaaaaatt ttacaattta gcttcagatt taaaagtaaa gtttaaaata ttatatttaa
     1621 atctaattta atattttttg ttttagaaat attattaaat taatatttct aatatatttt
     1681 ccctggattt aaaatatttt tagggtcaaa agctaacttt atatttttaa ttaacatcat
     1741 ataagcatct gaatttgatt catgtaagta ctctttttta gcatatccta tgccatgttc
     1801 accagaaact tgaccactaa gttctctaga ttttttatac atatagtcaa aagtttcttt
     1861 taatcttatt ttccatgtat tatcatccat accatctttt aaaatatata tgtgtagatt
     1921 tccatctcct gcatgaccaa aactttttat tcttattttt aatttgtctt gaagctcgtg
     1981 agtgtatctt ataaactctg ctatcttatc tcttggaaca acgacatcac attcatccat
     2041 ttgtgtcgta gatgccttta tagcttctaa aaatgcacct ctggctgacc atatagaatc
     2101 gtttctttct tgtgtatctg atataaatac atctaatgca ccattttcta aacataaatt
     2161 agctactttt tcatattctt tttctatatc ttcagtgcta tttccatcaa atgtaagtaa
     2221 aagataagca tctgatgtat tatctggaaa ctttttacct aaaaattctt ctgctgccaa
     2281 tattacatct ctttccataa attctatagc cgttggtatt gattttgatt ttattatttt
     2341 aggaacagtt tctattgcca ttgataaatc tggaaatggt ataagcaaac ttatactttt
     2401 ctttggtaaa ggaagcaatt ttaatatagc tttagtaact attcctaaag taccttctga
     2461 gcccactaat aaatccttta tactatatcc agaactattt ttaaccacct ttccacctac
     2521 atttataatt tctccatttg gtagtacaac ttcaagacct cttacataat cccttgtaac
     2581 gccatatttt actgctctca taccacctgc attagtgttt atattacctg caattgtagc
     2641 acttttttca cctgggtcag gtgggtaaaa taaatctcta tcttgaacat attgacctat
     2701 tgtcatcaat aaaacacctg gttctactgt caatgttaaa ttttcataat caacttcaag
     2761 tattttattc attttacata gattaatcat tattcctcca tttatggcaa cagcagcacc
     2821 tacaagacca gtaccttgac ctcttggtgt gactggtata ttatttttat atgcgtattt
     2881 cattatttta gatacttgtt cagtttcaag tacatttact aaaacttcag ggtacttctc
     2941 aatccctcca agttcatcat gtgaaaaatc ttcatttata tcacttccaa ctaatacatt
     3001 ttcttctcca caagtatcta ttaaaaaatc tatatctttt ttatcgatta atttatacat
     3061 ttctatcccc ctatttagct gctgatgcca tatatttttg attattatct ttgttatttt
     3121 ctattttttc aatcaattta ggaataatat cataaatatc acctattaaa gctagatgtg
     3181 ctacatcaag tataggcgct ttatcatctt tatttattgc tactatatag tcagcaccct
     3241 gcatccctgc aacaaattga acagctccag atacaccaca agttattatc aatttaggtt
     3301 ttacagttct accactaaga cctatttgtt ttttagcatc tatccaacct gcttctatta
     3361 caggtcttgt tcctgccact tgagcgttta acttatcagc taatttatat atcatctcca
     3421 tatcttcttg tttttttatt gctctgcttg ccacaactat cacttcagct tcttccagac
     3481 caacttcttt atttttttct tttacactca gtaccttaat tttagatttt agttcttttt
     3541 tttctacttt acataaagtt atctttcctg tagtattctc tattttttct ggtgctgaaa
     3601 atattttata tcttacagtg gcaaattgtg gtctattatt aggtgtgttt atatgagcca
     3661 ttatatttcc accaaatgct ggtcttattt ggtctaaatc agtatttgat tgaatatcaa
     3721 gtattgtaca atctgctgta agacctgttc taaatctagc ggcaagtctt ggagctaatg
     3781 acctacctaa tgtagttcca ccaactaata ctatcgttgg ttttatttta tctataaagt
     3841 tttctattgc ttttgaatat ggttctatcc taaaatcttt aaattcatct tcatcatata
     3901 caaatacttc atccacccca taagaaatca aattactgca cttatctttt atgtcttttc
     3961 ctacaaatac acaatacaca ggttgtttta tttttgatgc catctcacga gctttaccta
     4021 taagctcgta cgttacagga tgtatatttc cattatgatg ttcaacatat actgcaattc
     4081 ccctccattc atctttatta atttgtactt tactactctc tataaattca aatgcgcctt
     4141 ttggtccact tttgacacac aacttgcaca tcttacagcc agcacttatt tctactatac
     4201 ctgacttttc ttctatagcc ccaaaaggac atatttctaa aattctcttt aagtcagtta
     4261 ttttatcttg atttacaact atctttgaca tttattactc ccccttacac caactttaat
     4321 tcctctaatt tatttacaag tgcaaaactt agttcatctg catttcctct tacaatattt
     4381 ttatctgtat ttggctttgg aggaaatatt cttacaactt gagtaggaga accgttaagt
     4441 ccatagttat tttcatcttt atcttcaaag tcatctaagc tatatacagg tatttctcta
     4501 tctttagtat taagttttaa tttaaatgaa ggtagtcttg gttgaaaaat gtctttttct
     4561 acagttatta aacatggata ttcaatctca catacttgta aatcatttgg catatctatt
     4621 tcaacaacta tactttcatc tttaacttca attaattttg taacgttagt aacatgaggt
     4681 atatctaaaa attcagctac ttcaggtccc acctgtgctg tatcaccatc agtagtttgt
     4741 tttccacaaa ttattaggtc tacctttccc atcttcttaa taccttgtga tatggtatag
     4801 gaagtagcca atacatctgc tcctccaaat ctcctatcac ttattaatac tccttcatca
     4861 gctcccatca taaaactttc ttcaattacc ttctttgcct gaggaggacc catgctaagt
     4921 acttttagat tcgctttctt ctcttccttt attctaagag ctgtttctaa agcatatagg
     4981 tcatagggat tcatttttga atctactcca tctcttttta gtactcctgt agtttcatca
     5041 acttctactg aagtcgttcc aggaacttgt ttaatacatg tcaaaatttc cataaagtac
     5101 actccttttt tatttaacta taactgatac tccatcaggt ataactacta ctttgctctc
     5161 cttaccaact atactagtcg ccatttctaa agcttcttta aagttaaatg catgtttcat
     5221 atgcattttt tttatcattt caggattaca cttatctgtt accattatca cagtatattt
     5281 agataatatt ctcgctagta tctgaaattc ccattggtct ggaatcgtat ctactctatc
     5341 gacacttcta attttatcta aaagttgttt tggagaatct gcatttgcta cattttcata
     5401 aaaagattga cctccatgac catcattaca tgctgaaatc attattatta ctccaccgtc
     5461 tttacaagta gcttcagctg ctgtcattcc tttaacagat tgataaatat tttggtctag
     5521 tggatatcca ccatttgtag ttacaacaat atcagatttt atagaattta cttttgataa
     5581 ctctgttaca aatctacatc ctttagtatg tgctttttcg acatcaccag caaaggaagc
     5641 aattattttt ttatctttat ctattacaac attcaatatg aatgctaatt ttgcaacttt
     5701 agctgcatat accatatcct catgaatagg attattattc aattttccag ttcttgaatt
     5761 atcactatct ataaagtcac tacagtgatt gtacattata gtctttgcag atgcgattcc
     5821 tggaagtacg ctttttctgc cacctgaaaa acctgcaaag aaatgaggtt ctataaaacc
     5881 ttctgctatc aaaagttctg cctcatatgc tagtttgttt atatataaat ctccacctga
     5941 aggcaatatc cctactttac acatagattt atcatcagta gatatatgca taactatatc
     6001 ttcattatct actatttctt ctcccatttt ataaattagc tcttcccttg tacttggcct
     6061 atgaaatcca gttgccacta taatcttcac atcaatttct ggattaacat tcctaatcct
     6121 tcttaatata attggcatag ttattctact tggtacaggt cttgtatggt cacttgtaat
     6181 tatgactaca ttctttttcc ccttaaccag ttcttccaga gaattagagc ctataggatt
     6241 attcatagat tcttcaacta tctcttcttg agtcttatgt tctatataat tatccgattt
     6301 tgactccaaa acaccgagaa aacgttcatc aggtatttct aaaatcattc cttgttttga
     6361 atacggtact tttaacttta ccatttttaa tctcccatta taataaacta taaaattggt
     6421 atgtggtcat accagtttta catttatatg atagtaccat tatctaccat ttgcaagaat
     6481 aatttatttt ataacaaact tttaattttc attttttcta taatttttac ttataaaatc
     6541 catatgttcc tttgctttct cacatgcaag ttctacatca ttttctacaa ctgcattgta
     6601 tatagcttca tgctgtttaa gcaatatatt ttcattaaaa ggttctgcga ttattttttc
     6661 tcttgcatct tctataaatc catcaaataa ttttgatgct gtcataaaaa gactttgaat
     6721 taaataattt ttacttaatg ttgctagttt actgtgaaat ttttggtcta ataataccag
     6781 tactcgatta ttatcttttt tattagtttc taccctcatt tcatctatta tatgtttcaa
     6841 ttctataact tcagaagaag ttattctctt tgaagcaagt tttgcaatct caatttctag
     6901 gattattcta agctctaata tatcttcaag tgtaccatta ttaagtttaa aaatcataga
     6961 taaaggttct attaaagttt tttctatatt tgtacatata aaatttcctt caccctgtct
     7021 gctttctatc actcccatag tctctaatac cctaatagct tcccttatgg aagttctact
     7081 cacattcatt tgttcagaca gttctctttc tgatagtaat ttatccccct tttttaactc
     7141 tccatttagt attttatatt gtatttgctc aattacttgt tcataaactt ttttactagc
     7201 tatactatta aacatttttt cctccaatat gataatcgtt gttgtaatat atatctatta
     7261 tatatcttaa gccattacat tcatatattt ttattacttt taatataata tcttataact
     7321 caaatttaca ggtgatatta tgaaaaaaaa taaaattatt gctttttttg ctccatctat
     7381 catagttgga gttctagttt tagggattat cctataccca aatgaagcta taaaatctgc
     7441 aagagaaggc ttttctatat ggtctaatgt tttagttcca tcactactac catttataat
     7501 tggagcaaac ttaattgttg atttaaaaat agtggatatt atagggttta tcatcaatcc
     7561 cataactaga tttgtattta atgtttcagg aaagagtgct ttagcttttg ctatatctac
     7621 agtatctggt tatccagtag gagtaagttt agcttctgaa tttaggagta atggacaaat
     7681 ttctaagtat gaagcacaaa gacttgtgtc tttttgttct acatcaggac ctttattcat
     7741 aataggttcg gttggtacag gtatgttcca aaattcaaac ttaggttatt taatgattct
     7801 ctgccattat ctaggaacta tattggttgg tcttttcttt agaaattatg gtaatgaaaa
     7861 tcttccaaag acaaaattgg atttaaaaac aaatataaaa aatgtaatca acattagaaa
     7921 ttcaagtggg aatggttttt ttgttttatt tggaaatgct gtatttaatg gagtaaatac
     7981 attacttaca gttggtggat ttgtaattgt tttttcagta gtatttaaaa tactatctct
     8041 ttttaatgta atctcattaa tagcatcagt tatatatttg cctctttcat ttttaggtgt
     8101 tagtaaagaa ctctgtcaag catttgtaag tggtctattt gaaattacta taggatgcaa
     8161 taaagtatct agtataacaa gttctccaga aattttaaga gcatctttag ctagtttttt
     8221 gataggattt agtggattat ccatcctagc tcaatgttgt acatttctat caaaaacgga
     8281 catagattta aaattataca tactaagtaa atttgcgcat ggagttttag ctgctatctt
     8341 tatatttata ctttatccaa ttgcaaactc tgctgtgttg gtttctagct ttgctgatac
     8401 atacaacgtt atatataata atttaatctg gttttattat cttagctatt atgatacaat
     8461 tcttcaaatt gtagtaataa tttatctaat ctcagccgta tttattgcaa aaaaacatat
     8521 gaaaacttta tctacaaatg ggaaactaat gcgatataaa aatacttttt tcactaagaa
     8581 attttcacga aaaaaataaa actaataaaa cttaactaaa tacttccatt tttttattat
     8641 atttgtcata attttaataa cctttttaat tagtttaaca gcatagttat ttcatcacaa
     8701 tttaataatt ttattagaaa tatttttcaa aaaattctcc ttaatcacat atatcacact
     8761 tgtataagtt tactggaaaa tttttccatt atataatatt tcatttatat tatataataa
     8821 ataccgacct aaacttacca aatcaaacta agaggagtgg ttgaaaatgg caacaagacc
     8881 tatagaaata gacgaatata aaaagataat ggaactatta catactggct ttacttatag
     8941 tgaaaatggc gttgaaaaaa gatttagaaa aaatcctaaa gttgcattgg cactaatgtt
     9001 agaagctaat ttaggtctaa gaatatcaga tattttaaga ttaaagatag gtaattttaa
     9061 aggtaatatg ttggaaataa atgaaaaaaa gacgggcaaa ttacagtata gaccagttaa
     9121 taaaaatata attgagtcca taaatgaaca tgcaagaaag tataatctta aatcaaatga
     9181 ctacttagta aatataaaga caaaggctat tcaaaaacag ttgaggataa tttgtaaaca
     9241 cttaaatctg tataatataa gtacacatag ctttagaaag ctctatgcta ctactcaatt
     9301 tgaaaagagt aacaataatt tagagttggt taaagaactt ttaaatcaca gctctgtagc
     9361 cactacacag cgatatataa gggtaactca gcaagctatt aatgaagcta gtgaaaattt
     9421 ctttattggt taattataac gtatacattt ttctattatc ttattaattc accagatatt
     9481 aaaaaagagt gtctcaaaat gaacttttta gttcatgaga cactcttttt ttataaaatc
     9541 aaatatattt ttattatttc aacactggaa aaaaggctta tctctctatt ttgagacacc
     9601 ctattaaatt ttcataattc ttgcataaac atattaatct atcttcaata attttttagc
     9661 tgattcactg taattatttc tttttacaat ttccaaaact ctatcaatct catgttctga
     9721 ctttgcactt acaaaaatcg ccaattcttc atcatctata atatcataac tatctacata
     9781 tttatctaaa cattctaaaa ttccatcttt attattatac ccaccaaatc taactactgc
     9841 actacactca tcttctataa gtccacttaa atccaatttc ccttttgaaa aagactttat
     9901 atttgaactc ctattatcta ttatatctat aatatctgca taaacagcac ttcctgttgc
     9961 acctcttcca gctcccttac ctacaaaaga aagttcacct actgaatcac ctactaaaat
    10021 aactacgttg aactcattat ctatctttga aagcatatta ttattgtcca ctaatgctgg
    10081 tctaacaaat ccacttactt ctcctgattc atacttactt ctagcaacca attttatctt
    10141 acaatttaat ttttttgcat attctatatc tttttcatct attgaagtta ttccttctaa
    10201 taataaatct ttccaatata ctatttttcc ataagataaa gtagacaata tagataactt
    10261 tctagcacta tcatatccta aaacatctgc atctggatta acttctgcaa atcccaactc
    10321 ttgtgcctgt tttaaagcga catcatacgg taaattttca tcatacatct ttgataatat
    10381 aaaattacaa gtcccattta aaatagcgtt tatgctcttt atattgttgc cttccagtga
    10441 ttctatcaat ggttttaaaa ctggaatacc acctgccaca gatgcttcaa acttgatgct
    10501 aacattattt aagttagcta attctataag gtcactacct ttttcagcca gtaaatcttt
    10561 attagctgtc actacatgta tttttttatt taacgctctt gttacataat caaaagctgg
    10621 atttaatcct ccaattactt caactagtat atcaatatcc ttgtcaaata tatcttctat
    10681 atcagtagtt atcttatcaa aatacttctt atacttgtgt ttttctttat ttttaactaa
    10741 aattccaaca acttctatat ctctttttga agtattattt tctattaaat caattaatcc
    10801 acttcctact gttccatacc ctaataatgc tatcttcact gtaacatacc cccatcattt
    10861 tgattatatt aaattattta tatatataaa tataccaata aaaaaagctt gagtataaac
    10921 tcaagccata tgacgggttt atactcatct ttcagcataa atgctgcagg atttagcacc
    10981 aatgtataat taaatatact ggttgccggg cttcacaggg ccagtccctc tgccactctt
    11041 gataagattg ctaatttaaa tttatgttta atagtataat acaatttctt ccaattgtca
    11101 ctattttttt aacttatttc cctaaaagga tataaactat tatctaacag ctcttttagt
    11161 tggtttaccc ttttttgtaa cattattatt tttagtcttt gctttcgcct gttcatgtcc
    11221 tggaaaaagt attttaggct cttcaatatt cctcttgtaa atagtaaatt taaaaccaat
    11281 agcctgcaca aattcagctc ttaaagcttc acatactgca ttagcagttt ctttagtatc
    11341 aagacctgca ttttctaata tagtaacttt tactaattct ctagttctta acataccatc
    11401 taattgctct aagaaactct ctgtaacacc ttctttacca atttgtgtag taggctttaa
    11461 agtatttgcc aaagatctta aatacgccct ttgttttcct tttaacatat tctcacctct
    11521 ataattctat acttaaatta tctataatct atatttaaat taattgtaaa actcaaattc
    11581 taattcataa attttaacca catctccatc ttctattccc atttctctaa gcctatcaaa
    11641 aacaccttga ctctccatag ctttttggaa atattgaagg gattccatat catcaaaatt
    11701 tacagaatac attattcttc taagtgcttt acctgtaact acatacacac catcttcaat
    11761 atctatactt aactcttctt cagtaccaat atcaagttct ggtctataca tttcttcttc
    11821 tgaaactagc tccacatctt ctacttcttt tagcatttta gaaacatagg ctattacttc
    11881 atctatgcct tgacgagttg ctgctgacat tttaaatact gtatatcctc tgccttctaa
    11941 ttcactctta aacttctcaa acttactctc atcttctaat atatcaaatt tatttgcaac
    12001 tacaacttgt ggtctctttg aaagcttttc attgtacaat ttaagctcat catttatctt
    12061 gtcaaaatct tcaatagggt ctcttccctc taatccagat atatctacaa tatgtatcaa
    12121 tacctttgtt ctctcaacat gtcttaagaa ctcatgacct aatcctatgc cttcagaagc
    12181 accctctata attccaggta tatctgcaag tacaaaacta tctccaaact tagtttgaac
    12241 aacacctaga tttggtgtaa gtgttgtaaa atgatagttt gcaattttgg gtttagcttt
    12301 agttacaact gatagaaatg ttgatttacc tacatttgga aatcctaaaa gaccaacatc
    12361 tgctatcatt ttaagttcaa gagttatcca tctttcttct ccatctgtac cagattttgc
    12421 aaaagctgga gcttgtctta ctgcatttgc aaagtgttgg ttacctttac cacctatacc
    12481 accttttgca actatagctg tatctccttc tttttttaaa tctgctaata caagacctgt
    12541 agcctcatct cttattactg tacctgctgg tacttttaat actaaatttt ctccattttt
    12601 accagctctt tttcctttgc ttccgtcgcc accattttga gcttgatatt ttttctggta
    12661 cttaaagtcc attagagttc taagccccaa atcaacttca aatatgatgc ttgctccacg
    12721 accaccatct ccaccgtctg gaccaccagc tggaacgtat ttttctcttc taaatgctac
    12781 cgaaccattt ccaccatttc cagccttaac aaatattctt gccttatcta taaacaaatt
    12841 cttcacctac ttaattaaaa acttttaatt agcattacca aaaataccat tataaattca
    12901 tcagtattat aagaaaaagg agtgcctcaa cactcctttt atgtatatta ctcagctatt
    12961 gctactggat atatactaac tttttttctc ttcttgtctt ttctttcgaa tttaacagta
    13021 ccatcaacta atgcaaataa agtatcatca ctaccttttc caacattagt tcctggatgt
    13081 attttagttc ctctttgtct aactattata cttccagcag ttactaattg accatcaaat
    13141 ctcttaacac ctaatctttt agatatagaa tctctaccat ttttagaaga acctacccct
    13201 tttttagatg ctaataattg taaattcatg tttaacatat ggagtcaccc cctacttttt
    13261 taaaattttt atattttttg ggtattcccg tttaatttct ttaaccgcta attgaaagtg
    13321 atttagtaat aattgtgcgt cttttacatg tgtatctttg actatacact ctatatgacc
    13381 ttcttctcct actacttttt caaattcaat cttctgtaat ttgtctaaag aatttataac
    13441 tgcaatagca ttagatgtaa ctgcagcaca tactatatca tagcctattt cagcaaaatc
    13501 agcatgtccc tttaaacaaa aaccttgcaa caagaaatca tcattataat aatatttaac
    13561 ttttatcata acttaaccaa taactaagcg tttatttttt ctacaactat cttagtgtat
    13621 gattgacgat gtccttgttt tcttctgtaa tctttttttg ctttatactt gaaaactata
    13681 actttcttag ctttaccttg ttcaacaact ttagcttgaa cagatgctcc ttctactact
    13741 ggagaaccta attttaattc tccatcttta gagcaagcta atacttcgtt taaagtaaca
    13801 acatcacctg cgttagcttc taatttttca acgaataata catcaccttc agaaacttta
    13861 tattgctttc caccagtctt tactatagcg tacattaaat acacctcctc ggcctcaaac
    13921 tcgccagtac aaggtacttc atttgaagat ttaaaccttt actgtgcggc attacaatta
    13981 ttaattataa aatatttaca ttttattgtc aactatttta tcgaaaataa cattggtttt
    14041 attgtgcttt aatgtactat ttgcgtttaa agaaatcttt atattatatt tttcaccaat
    14101 tttatcaatt atatccatat aatattcttt tatttgttca aaaataaaat cattaaattc
    14161 taccattatg tttttgtaaa cagtatgttc acttattctc ataatttctt tttcaatact
    14221 atctagtata taatgtacag attttattgt ttgttcacca tcacaacatg gacaagacat
    14281 taaataatac ttatcaatgg attctttttc tctacgccta gcaacttcta ctaaaccaag
    14341 ttttgtcata cctaatactt caacttttct tttatcttta ttaaattctt cttctaggat
    14401 gtgtaaaatc tccttttgat gcttcttttt atgcatatca ataaaatcga ttattattat
    14461 cccagctatg tctctaattc taagctgtct tacaatttct tttgcagctt caagattagt
    14521 tttataaacg gtttcatcaa gtttaccagt tccaataaac ttacccgtat ttacatctat
    14581 aaccgtaaga gcttctgttt tttcaattat taaataacct ccactcttta accatacttt
    14641 tttatttaat aatttttcta ttttagattc tattctgtat aaatcaaata catctctatt
    14701 ttcctcaaga cacagtttat caacataagt cttatctatg cctcttaaaa tagacttaag
    14761 ttcagagtac ttatcataac tattggtaat tatagattca atatcatcat tcacattatc
    14821 ttttacatat ttagttgcaa aatctaaaga cttatataat aatttcggac ctataccaag
    14881 tttatattct tttaaaatgt tttcatactt taatttcaac tcttctatat ctttctttat
    14941 ttcatcatga gtgcaacctt gagcctcagt ccttattatt aatcctagat tttccttatt
    15001 tactgcctta gtaatttttt ttaatctaaa tcgttctttt tcatcagtaa ttttatttga
    15061 tattgtagtt ctatcattgg aaggtatata gacaatatac cttccagaaa tactaatctc
    15121 agtgtttaat tttgcgcctt tagttcctat ttcttcttta tttatctgaa ccaaaatatc
    15181 ctgaccagat tttatagtac ttcccttttt taattgtaaa taagcaagtt tcttaaatcc
    15241 aatatctaca aaacaagctt ctattcctgg tataactttt tttacgattc cacgatatat
    15301 attggataca gtcttcttat ttaaattgtc ttcaacaaaa agttctgtta atctttcatc
    15361 ttcaagtact gctgttttct gggaccctat tagggactca ataactatct ttttcacaac
    15421 ttcacctctc gagcttacat aggagtcact aattccccat cttctaatac atataaatct
    15481 cttctcaata tatcaacatc taatgggtca atatcaagtt caaacatctc taatatcttt
    15541 ggtataagta tattagtatt taaattagtt tttgagcctg tagctatagt agcagtaaga
    15601 gtaatatgtt catcttctaa atttaaaaca tcaaaggttc ttatcatagg tcttatatct
    15661 acttcaacca tcttaccttt tttattcttt tttgttatga ttatttcttt attattcata
    15721 aagtcaatta cttttctttt tacaaactct ttcgtcatag gtcttttcaa atctatatta
    15781 aacaaatatt ctccatagtc tatcacagaa gaaagagaag gtgtttgtct atcaatttct
    15841 tttgctttga taaaatctat cccatctgga agttgaattg atactttatt taaaaattcc
    15901 tctactgata aatcatcttc ttctatttca atatctacat actcaccttg actttctgtc
    15961 cctaaagcca aagcattgcc ataactcatt ttagggtgag gattaaatcc ttgagaatgt
    16021 gataagttta tttcagctct tctaaacgct ctttgtaaca atctctgaag gtcaagatgt
    16081 gatatatata tcatgtcgcc ttccttttta aattttactc ttattatctt actcatatta
    16141 gcaaagcccc cttcctatat catgtatatt tattccacaa ccattgcagt tatgtctaca
    16201 atcagaagtg attttttctt ttttagcatt ttcgtcttct ctaattaaga attttttact
    16261 aatacctaca tctatatggt cccaaggaaa tacctcttca tagtttctat ttctatgtgc
    16321 ataaaaatct atagaaagat tattcttttc catagcttct ttccatatat ctaaattaaa
    16381 atgttctgcc catccatcaa atttagcacc tagtctaaat gcatcatata taacttttcc
    16441 tattcttcta tcgcctctag ctactactgc ttccatcaaa ctagtctttg aatcatgata
    16501 attgtatttt atattgttat ttcttaattt atttactaaa tgtctctgct tattaataac
    16561 ttcttctgta gtatcttgac catgccattg gaaaggtgta aatggctttg gtacaaatgt
    16621 agaagtactc actgtaacac taaaacttct ctttagcttt cctccattta cttttctata
    16681 aatatcaata actttataag ctaatttagc tataccatct aaatcttcat aagtctcagt
    16741 tggtaaacca atcataaaat acaacttaac actattccac cccatctcaa aagctctttc
    16801 tgttgcattt tccaaatctt cttctgtaac acctttattt ataacatctc taagtctttg
    16861 agttcctgct tctggagcaa aagtaagtcc agattttctt acttgttgta ttttatcagc
    16921 aatttccatt gaaaaattat ctaatctaag ggatggaagc gaaatcccaa tattattaga
    16981 tgcatattca tctaccaaat aatcagtcaa ctctgataac ttactataat cactcgtact
    17041 aagtgatgat aatgatattt catcatatcc agtattctta actaatttat ctaatatttc
    17101 tttaagtctt ttaacactct tttctcttat tggtctgtat atcatacctg cttgacagaa
    17161 tctacatcct ctagtacatc ctctaaataa ttctagtact attctatcat gaacagtatc
    17221 tatataaggt actattagtt tttctggata atctacagtc tcaacatctt ttattatcct
    17281 tttagtagga tttttagtaa tcccgtctct attaggagtt acactttgaa ctgtaccatc
    17341 ttcattgtac ttgacatcat aaaaacttgg tatgtatact ccttctatgc tagatatttt
    17401 atataaaaaa tcttctctag tcgttttatt tttcttccat tctttatact catttactac
    17461 ttctaaatta acctcttcac cttcacctaa tattactaca tctacaaaat ctgctaatgg
    17521 ttcggaatta taagcacaag gaccaccaac cattataaat gggtctttca aagttctttc
    17581 ttcttttaat attggtatat tggctaaatc taatatattt aagatattag tgtatgaaag
    17641 ttcatattga agtgtaaaag tgacaaaatc aaagtttgtt ataggctctc ttgactctaa
    17701 tgcaaataat ggtatacttt tttctctcat tatattttcc atatcaactg caggagaata
    17761 cactctctca caaaatacat cttcatcctt atttattaca tcatataata tatgactccc
    17821 taagtgactc ataccaactt catataaatc tggaaagcaa tgtgcatatc ttatcaattc
    17881 actattacta gtatctttat gaattgaatt tatttcattt ccaagatatc tagcaggctt
    17941 ttctactttt tttaagattt ttttcaagtc tactttattc atttattaaa attcctccaa
    18001 acaagctctt tatttttatt cttatttaca agtaatatta tacacgataa aatattttct
    18061 atcaaaaata taactaaaat attgaattta aaatacatat tattcacaaa atagaatagc
    18121 taaaaatatt taagaatatt ttctattaaa tttttattga aatacaattt ttttacaaag
    18181 tatgatatat tataaacata aaactattgt tttacatgac ttatcatgac atcttttgtt
    18241 tcattcacct caaaatgggg tatgttacct atataatgat aaattttagg agggttaaaa
    18301 atgagtaaag tttttgaagt aaaaaaagat atctacttta ctggtgtagt agatgaaggt
    18361 ttaaaagtat tcgacataat aatggaaact gagtttggga caacttacaa ctcttattta
    18421 atcaaggacg aaaaaacggt tttatttgac actgtaaagg caaattttaa agatgagttt
    18481 ttaagtaatt tatcagaggt tactgatata gctaaaattg actatgttgt aattcatcac
    18541 acagaaccag accatgcagg tagtttaaaa tacttattag atataaatcc taatatagaa
    18601 gtttattgta ctaaagctgc taaactatac ttagatggtc aaataaatag accttttaac
    18661 tgtcatgtaa taaaagatgg tgaaatttta aatatcggta aaagaaatct tagatttata
    18721 actgctccat tcttacattg ggttgataca atgtttactt acattgagga ggacaagact
    18781 cttttaactt gtgatgcatt tggttgtcac tttgcaagtg ttgatgcaga ggtagtgaat
    18841 agtgaagatt atctaaaatc agctaaacac tactatgatt gtatagttaa gccatttgct
    18901 aaacatgttt taagtgctgt agataaggtg gtaggactaa acatagaatt tgatactata
    18961 ttgacttctc atggtccaat gcttactaaa gacccaatgg ctgctgttaa aagatatgtt
    19021 gagtggtcta cagaagctgt taatacaact aatcaaaatc aagtttctat attctactta
    19081 tcagcttata gtaatacttt agagatggct aaaaagataa aagaaggact tgataaagaa
    19141 ggtgcaaagg ctgaattata tgatttagaa gatatgacat taacagaaat gcacgataca
    19201 ttagtagtgt caaaagtaat attactaggc tctccaacta taaacaaaac tatggttaaa
    19261 cctatgtggg atttattctc tgttatagac ccaatggcta accaaggcaa gatagcagga
    19321 gtatttggtt catttggttg gagtggtgaa ggtataacta tggctgagac tttacttaaa
    19381 tctatgtcat tcaaaatgcc tgtagaatct cttaagaaaa aattcttccc tagtgaagag
    19441 acattaaaag agtgtatggc atttggtgca gaatttgcaa aattagttaa atagccatta
    19501 atcacacata atattattta aaataaatga ttttatattt aaaaataaat taaaatggag
    19561 ttgtctcaaa attaattttt ctaatctaat tttaagttca actccttttt tattttctaa
    19621 aatgactgat ataatgataa atgcaccctt tgtgcgaggg tgcattattt ataatatgtt
    19681 ctatttgtac actagtatat ttgtattaat tcacatatct agcgtatgct accatccctc
    19741 ttccagaatt agatgctgtt tcaccaattt ccactttaat aattatatta ttttttttac
    19801 agtattttga taattctgct gcagaacggt tcttcccagt aaaatctaaa gaaaatggct
    19861 tatcatattc aaaaggataa ctaacaggtt tactctctgg tgctaatgca accataccat
    19921 attgtgtttt cttaaatcct attacataaa ctgtatgctt tgatgggtct aaatttgaat
    19981 tactacttgt aaacttaatt gtatttattg atgagtcgat tgaactacat ggaactccct
    20041 catacatttt gttttgtggc ttcatattat ttccataaac ttcattaagt attgaccctt
    20101 cttggtctgc tatcatagtt tgattcccag gtccaactgg cgcagaaggc ttagctggcg
    20161 taggtttctt aacagttggc gttggattct gtgtctttac tacttcgcca acagctggat
    20221 atgctttctt gtcaaatggt aatgggtgag taagactctt gtatatgatg tctgctcctg
    20281 ctgatttgtt ggcatcaata tctacatgat acaaacgtcc atcctcaaaa cgaataagat
    20341 tccactgatg gtcatttgtt gtactatgta cataataaca ttcaattccc ataacatcac
    20401 ataaagcttt caagctccta cacattccag aacaagcacc ttttttagta accaatgtat
    20461 aagcagtatt ggctccctct gctgcgttcc agttaacata tgttgtgttg tttttaatgt
    20521 gattataagc aaccctaatc ttagcatctg tggtcatgtt ctttgtaatt ttcttgttca
    20581 taaagtctgc tgttgcttgt gctaccgaat taagttgagc ttgtgacaac tttggaccat
    20641 atatactgtt ggttccagct acatagcttt tcggtgtctt tgctgtaacg tctttagctg
    20701 tcataccata aactgttaca ctcatacatg aggttaaaac catcattgca atcaatagtt
    20761 tagtagctaa tttcctgatt tttttcatat tagcattctc ctttataata tatttttact
    20821 ttcaattccc taccattaat taagttcatt ttagatttaa aatatggatt atcaacatgt
    20881 gtgcatagcg attcacgtgg tcatagaata tttagatttc ttggaaaatc tgttctatat
    20941 ttcctatata gttcgtatac aatccaactc acaaacctgc atttttgata tcatcacaat
    21001 aaaatgataa taattaatat attcaaaaat gttggtctgt aacaggtatg tcaatttcca
    21061 attatcggta atagcgagag tgaggagaat tgtcaataat gcatttaaaa ttaaaattgt
    21121 atacacttca tacattctcc cccaacaaca ttatacagat tataatttgt atattcaata
    21181 cattttttgg aaagtataat tatatcaaaa tatgtgatta tgtatagata caatccacta
    21241 tggagaaata taaaagaaaa gagtataaca aacaataaaa aataagatga ttcaaatttt
    21301 attttgaaac atcttattta ctctacaaat taaaattatt tggtgaatta tttaattatt
    21361 attttttatt aaagaaattt taaatcttaa tataaaatac gctattatac ataataatcc
    21421 aaatacgaat gctactggaa ttaacatctc cgattcaaaa taaaagaaat attctaagaa
    21481 aatatctgga tttactatat tcccattctt gtctaaaaaa tcttttccat tatatcctaa
    21541 atgctgtata aaattactta tgttattata atctgcttca ctctcataca ccatattagc
    21601 attcaatcca gaagagctta aattagtgtt tccatctttc atatctatta catatagtct
    21661 aagagctttg actttactat acttatcttt atcaagtatt ttttcaagtt ctaacttata
    21721 ttcaccaatc tttgtcatat catgtctttc tgccaattgc tttatttctc catcaagttc
    21781 ttttcctaaa ttatacatat tatgttgtaa actattattg taataccaca taaatccaga
    21841 aattaaaaat gcaattatac ttatgtaacc taatactttt ttaaacccca ttacaatgga
    21901 tttatgccta tccaatgata aagatagttc ttttattata ttacataatt catactgcat
    21961 ttcatcacca tcatcaaatc tttcaattgc ttttttacat gcttcttctt catctaaccc
    22021 ttctaattta aattcatttg cagattctat aagatggcat ctcatttcct gttttaattc
    22081 tatagtactt ttattgtcac attttttata tagtttatct aaatattcat ctattagttt
    22141 cataaattaa tccacctctc ccaaaaattg attcataacc tttttaataa atctccattc
    22201 ttgtttcttt atttctagaa aatctttacc ttcattagtt aaattataat attttcttct
    22261 tccacctgaa ctttgttcat tgctataata agatttaatt aaatttttag attccattct
    22321 tttaagtgca agatacattg ttccttcttt taattcaaac tcacttcttt ctcttacttg
    22381 ctttgcaatt tcatatccat aacaatcttt cttttctaat atagaaacaa ttaatatatc
    22441 gatataacct tttaacactt ctttatttaa ctgcattatg taccaccgcc ttttcaccta
    22501 ctactctata atgtatagta cttatattta ctataataat acatagtact ctataatgca
    22561 atgtttatat tctacaatag acttaaaaat aataaatagc tgtatattaa tatttaatct
    22621 ataaatacta atatacagct atttatcaaa ttttaaaaat aagtttttat tttattaatg
    22681 ttgtcataac aacatttact tgattgaaat agtattacct ataagtttaa atatatataa
    22741 taatagactt gattctattt catattatta aaatagagta atagtttaaa ttctactact
    22801 ctatctataa tctatttcct aattatttaa tctcaaattt agctcttcat catttaaatc
    22861 tttcataaga tttatacagg tactaggttt attgcaacag aaagactagg gcattaaaca
    22921 cttatatatc tgtttcttta gactgtaata ttagtatttt ttaaatacgt tgacttttgc
    22981 tttttctaac ttctctccat gatagttctc ctctatcaag agcttttata aatatttctg
    23041 ctgaagctag atttgtagct attggaacat gataaacatc acaaagtctt attaacgctt
    23101 gtatatctgt ttcatgagcc tgagatgtca atgggtctct taaaaaaata actaaatcta
    23161 tttcttgtgt tactattaaa gaacctattt gttggtctcc acctaaagga ccagatgcta
    23221 atctatttat atttaattca gtttcatcca ttattctttt tcctgtagtt ccagttgcat
    23281 ataatccata cttttttaaa attgattcat aacctataca aaatccgacc atagtgtttt
    23341 tcatttggtc atgtgctact aatgctatat tcatatatct aatctcctca atttatgttt
    23401 agatgtattt aaatttagaa atttattttc tttcttctca tacacacatt tagtactaat
    23461 cctaagtttg ctaaagatgt caataacgaa ctacctccat aacttacaaa aggtaatgtt
    23521 actccagtta ctggtattaa cgcaactgtc atacctatat tttggattat ctggtaacca
    23581 aacattccca taacaccaac cacgatgagg gttccataaa aatcttttgc atctcttgca
    23641 attgctaaaa gcctcaatag gaatatcata aataagatta tcaacactgc cattcctatt
    23701 acaccaagtt cttcacctac aacagcaaat ataaaatcac tatcttgtac aggtaaaaaa
    23761 tcttcttgat tttgacttcc attgtaaagt cctttaccag ttacacctcc agaaccaatt
    23821 gcaattagag attgcataac ttgatagttt ccttttagtg ttacatcttc tggatttaga
    23881 aaagcttcta ttcttatctt ttgatggtct gccatcatta aatacatcag tggcattgac
    23941 accaatagta tgattattcc tctttttatc aactttgagc taagacctgc tgtgaacagc
    24001 attgcaaata tcatacaaca aaatacaatt cctgttccca agtctggctg tgcaatcaat
    24061 aatccgataa atggaagaga ataaactaca acaggcataa cttcctttaa tgtatttaat
    24121 ttatcctttt tggattcaag tatctttgca taacttagta caaatgttaa tttgactatt
    24181 tcagatgtct gcaagtcaag tggccctaag ttaatccacg acctagctcc accttttact
    24241 gtcccaattc caggtaataa aactatggct aacaaaataa gacttattat ataaagcgct
    24301 ttataatacc tgcctagaag gttatagtca aaaaataata tgactataat cattcctata
    24361 ccaagtacaa aagctaatcc ttgtttaatc aattgattat atgaacctgt tgaattagca
    24421 tgtgttgcac tactaagtat aacaagccca aaaataaaga tagctaatac tgtaactata
    24481 agtttccagt ctaactgttt tatcaactta attgtcgact tataattaat attgattttt
    24541 ttcaaagaat caccgtcttt ctatctttaa acatataatt aaataaaagg ggcatatacc
    24601 aataaggata tccccctttt aagcactaat tacatacatc tatcttttat attctttagt
    24661 ggtatattag caactaatgc agatacaggt ttgtcatcat gctcacctct gcatttagac
    24721 atttttattt caagaccatc atcttctatt tctgcataat tagctattac ttttaaaatg
    24781 tctgttttta tcatctctaa aagttgtggt gaacaatcta ctctatcatg aactaaaact
    24841 agctttaacc tctctttagc aacagattta ctagttttag cctcgttaga aaaaactcta
    24901 aataaatcta acacagatgt atcctccttt gctacttagc catgctaaac atttttttaa
    24961 gtctaccaaa gaatccatct tcaacttcaa gatcaagtag aggaacttct tcatttagta
    25021 tcctttttgc gatatttttg tatgcttgac cagcaagtga cttagaatca agtatagctg
    25081 gctctccttt atttgttgat ataattatgc tttcatcatc aggaacaaga cctaacaaat
    25141 ctattgctaa tatttctatt atatcttgtt tatccatcat gtctccacgc ttaaccatat
    25201 catttctaat tctatttata actaatctta tctcttttat ttcatttgct tctaatagac
    25261 ctattattct atcagcatct cttactgctg atatttctgg attagtaact acaatagctc
    25321 tatctgcccc agctactgca tttttaaagc cttgctcaat acctgctgga cagtctatta
    25381 ttatatactc gaaagattct tttagtttct cacacaggtc aatcatctgc tcaactgaga
    25441 cagcattttt atctctagtt tgtgctgctg gtaataaata tagattatca aatcttttgt
    25501 cttttattag agcttgctta agcctacaag ttccttcaac tacatctact atgtcataaa
    25561 ctattcgatt ttcaagaccc attactacat ctaagtttct aagtccaata tctgcatcca
    25621 caactactgt ttttttattt tctaggctta gcgcagttcc taagtttgct gcggtagtag
    25681 tttttccaac cccaccttta ccagatgtta taactataac ttcgctcata atactacccc
    25741 ctatttttct ttctatttgt ctaactttga caaatagctt tcgattacaa ttcttccatt
    25801 acttacaaag gctatttctg ggctaatttc tgattcattt tcataatttt cttcatcatc
    25861 tggagcttct gcaatattat ctgctatttg taatatttta ggattaagat ttccagcaac
    25921 aacatatgca aattcattgc cttctgcacc tgcatgtaca aaaccttcta ttttacccat
    25981 tacaaaaaca ttacctcctg ctacaacctt agcaccagca tttatatctc ccataacaac
    26041 tgtatttgat tttgaaagga cttttgaacc aggtttcata tcattcaata taactacatc
    26101 accttcaaat tcaatatttt caccagatct tagggtattg acatattttg ttggaaaatt
    26161 actattttct tcaatttttt gatcttcaac aaattccaca tcaaatctag aagtaattcc
    26221 ttctttaagt tctagaatct ccatgtcagt taaacaatca ctattaattt tactaatttt
    26281 agccccatta aaaaagccaa catatgcttc caatttgttt attatttttt cctgtatttc
    26341 ctcaaatgga gcttctcttt ttatatttac tattatccct cttttattac ccttgaactc
    26401 tactagttct tgactacaaa tttctcttaa agacataaca acctccagag tgatatatca
    26461 tttatattct tcaaatacgc tttaaaccct tttatttttt ctatataaag ctaaagttta
    26521 tacatagatt gagctatcta ttaatttgtg actcgaaatt tatattttcg tcagaagaat
    26581 tgttaacatc attcgtcttg ttgtcatttt tactattagt tggctctaat cccatataag
    26641 ttccaataac ttctctagtt ggtaaaagtg agaatacact tgaatcacct tgaggaatta
    26701 cacatacaac agctatttct gggtcatctg ctggagcaaa agcaacagtc cacgtaaaag
    26761 aaccataatc ttgtttaaat ctatctattt ggtcatctgt tatttttgga tttaattctt
    26821 ttatagcttt tcttagatat gaagaattca ccttatcagt gtcctctaat ctaactttta
    26881 ctccatcttc taattcttcc tctaatttct ttctttcttc gtctttcaaa tctttatttt
    26941 ctaatttctt ttttatttcc ttttccttag ctaatgaaag ctctttttct ttttctgctt
    27001 tcatcttatc agctagttta atcgcatcat ttaggttgac attataagat gacatatgac
    27061 tttttaaata ttcatactcg ttatctgtag gtattttccc acttttctca gctgtaccag
    27121 tttttgctgc tacatctatt ggaaaatcag caaaagcact cttcgctgta ccttgtcttg
    27181 caaccaattt catacctttt gttaattctt ttaagttatc tggattttta aaaggtattt
    27241 tttctacttt cttctggtca ttaattttaa ctgatgaata atcacttgaa acagctctat
    27301 caactacaga taattctact aaattacctc catttgctat ggcagctaca tatcttgata
    27361 tttgagctgg tgtataagca ttttcacctt gacctatagc taagttgaat gtatctgcag
    27421 tactccattt tgcaaaatta aaataactga atactgctaa atctgctaca tcttctattc
    27481 tatcttcttt aacattcatt ttctttagcc tattcattgt ttcgactcta ccaggagttt
    27541 tcttttctgc tgcccagctt acaatctcat tgattctttt ctcatattct ttaggatttt
    27601 tttctctagt tatatcaaca aaatcatttg ccatttctct ttctaaattt gactttagaa
    27661 gagcttgtgt tgatttcaat ttatcttctg tgctaggaac tttgcctgct ctttcttcta
    27721 cttcatcttg aagccctgta ttttggtcaa gcccaaataa ttttgcatac tcaagtattt
    27781 tatttgcatt catatctata ccaatgcttt ttccatctgg ccatgtttta cctgtaccaa
    27841 ttgttgccat atatatatta caagactctt gtattgcttt atataagttt gtcataccat
    27901 ggtttcctct accatggttc catacatagt caccaaaaga ttttttacct aacattataa
    27961 ccccagggtc atttatagta aagtttggat ccagaccatt ttctaatgct gccattgaag
    28021 ttaccatctt aaatgaagaa cctggctgaa attccccttg tgtaaccaag tttaaaagtg
    28081 gacttcctgc tagtaagtca tttggatttt ttggttgaag tgctttataa tcctctgtag
    28141 aaataccttt tgcaaattta tttgggtcat aattaggata acttgatgaa gctaatactt
    28201 ctccattttt aacatcaata gctataagag ctgctgactg tgcttttcct gcatatgcac
    28261 taattggttt gtccccaaat ttacttttaa aagtacctcc tttagaagca acttcgatta
    28321 tctgttttaa tgcattgtct gaaacttctt gtaaatcttt atctagtgta agatacacag
    28381 tatctcctga tttaggtttt ttagattcaa tttctttact gattctaccc aatgcatcaa
    28441 ctttaaccat tttataacca tcagttcctc ttaatctact ttcattactc ttttctactc
    28501 ctgcaagacc taccatatct ccagtttcat aacctttttg aaggtatgat tctatttgag
    28561 tggatggcat ttttcctaca tatcctaaca tatgagaagc taatgaccca ttaggataat
    28621 atcttactgg ttctactgct attgaaacac caacaaggtc catagcactt tcttcaattt
    28681 gagcaatcgt agtttctcct acatccttag caatagttac tggattatat tgagaatatc
    28741 cttttgattt tatcaaatcc cttacgacca ttatttttct tgcatcttca tcactcaaac
    28801 ttttatcaat ttctaatgca tcactatttc ttactttttc aaacgcttct ttggcactca
    28861 gtttagtttc ttttatctta taactagcca accaatctct cttatctctt tctgctgtga
    28921 acatccattt actaactaaa ataggtggat aatatccatt ttcatttagt tttgcctgta
    28981 atcttgtcgc atccaatctt ttatcttctt gagataatat tccagctgat ataagtttgt
    29041 ctactaagta ataaaaactt tccttagcat tataatcatt tggaatacca ttttccgatt
    29101 tatattccct aatatctctg tcatatgtat aatagtactt tccattttct acatatatag
    29161 gaaactcatc tacatattct tcaccatttc tctccagcaa atttataagt tttaatgata
    29221 tttcatttgc tcttgaatgc ttatttgcat ctttcttatt aatatcgtta cctgaaactt
    29281 gaacagtaaa taagttttta tttcctgcca acagtcttcc atatctatct tttatttctc
    29341 ctcttggagc ttctattgcc aactttttat atgttttatt ctcagctaac tcattgtaat
    29401 attcatattt aaatgtagtc atatagatta tttttactaa aatagctaaa aatatcacgc
    29461 ccatgactat cttaattatt tttagtctat caacttgttt attttcttcc atgaaatcac
    29521 caactaatct tctttaagtt ttaaaactgc tcttttagat aagcgatata ttactaaacc
    29581 aattaaacta ttcactattg gtgctactag tagacctttt acaaaaagtg ttgatatgtt
    29641 gtagctttga taaattatac tagatgtacc tatattgaca attgaatcaa ttaaactgcc
    29701 tataaaaatt aaaacgaaag taataatata actaccttta tatagctgat ctctcatgta
    29761 tccaattgca tatgcaataa taaacaaaat taatgcattt acaccaaaaa ttccaccaac
    29821 ggttatgtct ttaataagcc ctattattgc tgctataatc ccaccttcta attcatctaa
    29881 ataaagagag attatggtta catatataag aactaaatta aagcttatgc caaaaatatc
    29941 tatataattt gttatactat tttctatagt cataagcaca atccccaaca gacaaagtaa
    30001 aacttttttc attgttttta tcccctttat cctatatttc ttggttctat gactacaacg
    30061 tcatttatat tcttaaaatc aacataaggt tttacaacta catattttaa tgacttatct
    30121 ttatcatcaa ccactttttc aacttcgcca attggtatac catctgggaa gaatccaaga
    30181 cctgatgttg ttattatatc tccttgaatt acattatatg atgagtcaaa catatatcct
    30241 tgcaaatatc ctttactatt ataactatct ttattatcta aagtagtatt ttgagtaatt
    30301 gtacctttag cattggcatc ctttgctagt ttaaagctta cagatgcctt agaatccaat
    30361 agtgaaattg ccttactata attgttggaa acttcataaa ctatgccaac taatccacta
    30421 ccattcataa ctatactttc tttttttaca cctgaatttt ttcctgcacc tatgacaaaa
    30481 ctctcatacc agtttccatc atttttacca acaacacttg ctgaaatact tgtcgcctta
    30541 tactcttctt gtacaaagtt cagtgtcttt tttaactctt ctagcgattc tgttttatct
    30601 agtttggcat ttaaagctat catatttttt ttaagttttt cattttcttc ttctaatttt
    30661 tttacctttt tagaattatc tttaaaattt gctacatctt taaaaccatt tttgataaaa
    30721 gaaaatccat catttattcc cttacctaca cttgtaatag catctgaagc tactcctaaa
    30781 tttactggac taccactaga aaatttacca attgatatac ccacaattcc aattaaagtg
    30841 atagcaacta cgcccgttgc tatcacttta acattaatcc tttttttctc atttttgttc
    30901 ttgtcaaatc tcaaggccat caccaacttc taattcttag tattcatcat taatactttt
    30961 tcaaagattt cttggtcttc aacagattta cctgttccaa gtgcaacaca atcaagaggt
    31021 gtttctgcta tttgtacaga cataccagtt tcctgtgtaa taagcttatc aagacctcta
    31081 agcaaagcgc ctcctcctgt tagcattatt ccgttttcca ttatatctga ggctaattct
    31141 ggtggagttc tttctagtgt agattttatt gcatctacta ttgaacttac aggttctttt
    31201 aatgcttctc taacttctgt agagcatatt tctattgttt taggtaatcc tgagattaaa
    31261 tctctacctc ttatttgcat atttatttct tcatcatctt taaatgtaga acctatgtta
    31321 atttttacat tttcagcagt tctttcacct atcataagat tatattcttt ttttacataa
    31381 gccactatag actcgtcaaa ttcgtctcca cctattctta tagatttagc agtaacgatt
    31441 cctcctaaag atattacagc tatttctgaa gtacctccac caatatcaac taccatatta
    31501 ccttctggtt cttcaacttt taatccagcc cctatagctg ctgccattgg ctcttctata
    31561 aggaatgcat ctttagctcc tgcttgtctt gcagcctctt ctatagctct cttttctact
    31621 tctgtaactc caaaaggaac acatatagct attcttggac ttacaacacc ttttttatca
    31681 gccgcttttt gtataaaata gctaatcatt gattgagtta tgtcaaaatc agctattact
    31741 ccatctttca taggtcttat agctactata tttcctggtg ttctacctat catttttttg
    31801 gcttcttcac ctactgctaa tacctcttta ctatcatctc ttattgcgac aactgatggt
    31861 tctctaacaa caataccttg tccttttatg taaactaatg tatttgcagt ccctaaatct
    31921 attcccatat cctttgtcat cttattaaaa ctaaaaaaac cttttttttc tttctttttt
    31981 tccttagcca tgattttact ccttcctact attaagaatc atgtttaaaa cattctccta
    32041 ttattttatc acatataaag tcaaattatc atattttctt taaagctaaa gtataatcca
    32101 tctccaataa ttatatggtc tattatttct attccaatta tttctccaca tttaataagt
    32161 cttgatgtga tatttttatc ttctcttgat ggttctacac ttcctgaagg gtgattatgc
    32221 atcactatta tcttacttgc acttcttctt atagcttctt taaaaacctc tcttggatgg
    32281 actaatgacg agcttaaagt ccctatagat acatctacat cagatattat ctcatttttt
    32341 gtgtttaaaa gaaccgcttt aaaaacctct ttttttaaat accttaggct atccatataa
    32401 tacctctgta tatcccaagg attccttatt ttatacttta taggtttaaa actagctact
    32461 ctagagccta gttctaaagc tgctttaatt tgggttgatt ttgataaccc aattccatct
    32521 atattacaca gctcctctat tgtcatatct tctaaatgtc taataccctg aatatctcta
    32581 tttattatat agttggctaa ttcaatagca tttttattct tgttgccagt tcttaaaagt
    32641 atagccaaca actcagcatt tgataagctt tttacgcctt tgacaagcat cttttctctg
    32701 ggtctttcct ctggtgccat ttcttttacc ttaatggttg aattaaatga ctttttcaga
    32761 taaatcacac tccataaaaa agatttatac taaaatattt ttttaatagg tcgcctaacc
    32821 ttgaaattgg aagaccaact atattaaaat aatctcctct aatttcttca actaacaaag
    32881 ctccataacc ttgtatacca taggctcctg ctttgtcaaa tgactcatta gttttcagat
    32941 aatcctcaat atcctgctct gataacgttt taaatttcac attgctgatt acatagtcaa
    33001 ttaccttttt atcttcgcac aagtttatta agctaatacc tgttatgact tgatgctctc
    33061 ttccagatag tctttttaac atatctcttg cacaagactc atcttttggt tttcctaaaa
    33121 tagcattgtc taaaacaaca actgtatcag ctccaataac aacatcttca ttatgttcag
    33181 atgctacaga catacttttt tcaaaagcta atctcataac taaatgtttt ggtgtttcac
    33241 cttccaatat aatctcatca atttcatttt taattatatc aaatcttaca ttcgtattct
    33301 ctagaatttc tttccttctt ggagaggctg atgccaagat tatattcatt tattcacctc
    33361 atttgtacgt aatttgtacc tatttagtct atcactatat tgtaaaaaat tcaacagaaa
    33421 tgtcgaacct tttttgttac actattgtta tatttattac cattagaata aatatacata
    33481 aaatagaggt atggaaatta ttccatacct ctgttttatg tactcattag agatatggaa
    33541 attattccat atccttattt tgtccatatt acaaaatttt aatagctttc tttggacatt
    33601 tttccataca taaatggcat cctacacatt tatctgcatc taccttatgt ttttctttta
    33661 attctccctc tattgcatca aacttacatt gttttttgca cactgtacat ccaacacaaa
    33721 gttcttggtc aatagtaact ttctttttct tagttatgtc acctgatatt acttttgtag
    33781 ggcattttgc tacacattgc atacaaccta cacacttatt agggtctatc ttagctattt
    33841 tgtcttcaaa tattattgca tcaaatttac aagcttttac acacattcca cagccaatac
    33901 atccagcagt acatttttcc ttaacagctt taccaaactc tttgctatta cactctacaa
    33961 ctacttcttg actttctggt tttgtgatta ttataccctt aggacaaact tctttacatt
    34021 ttccacaatt tacacacttt tcttcatcta ttactgctat tccatcaact atagaaatag
    34081 catcaaattt acaagcatct ttacatgttc caagacctaa acatccaaat ttacacatct
    34141 tagcacctga gtttaaaaca tttgctgctc tacaatctga tattccttca tactcatatt
    34201 tatcttttgc acttgaacaa gttcctttac aaataacttt tgctacttgt ttctcacctg
    34261 cttcagcact tattcccatt atttctccaa cttttgcacc aacatctgct ccacctacag
    34321 ggcaaccatt aactggtgca ttgccttcaa ctatcgcatt tgcaagacct ccacaacctg
    34381 gaaatccaca acctccacag ttggctcctg gaagtactcc tagtatagct tccactctct
    34441 cgtctacttc tacagcaaac tttttagatg caaaatctag tactatcccg aagattaagc
    34501 ccataattcc taaaactaat acagctgtaa gtatcaccat tttcacccct cttttttata
    34561 gctttataag tcctgtaaat cctaagaaag ctattgacat taaacctgct gatataagcg
    34621 ttatagggaa acctttaaat gcttctggta tatcagctaa ttctagtctt tctcttatac
    34681 ctgcgaatat tactattgct aaagtaaatc cagctccggc tccaaatccg tttattattg
    34741 tttctactaa attataactt ttttgaacat taactagagc tataccaaga actgcacagt
    34801 ttgtagttat aagaggtaaa taaactccta atgcttgata taaagatgga ctcatctttt
    34861 gaattaccat ttcaacgaac tgaactatag aagctataac caatataaaa gctattgttt
    34921 gtaagaatcc agttccagtt tttactaata aaatctgtat aaaataagtt ataattgaag
    34981 ctagagttaa aacgaacgta actgcaactc ccatccctac tgctgtatca accttcttag
    35041 aaactcccaa gaaaggacat atacccaaga attgagatgt tataacgtta ttaacaagaa
    35101 cgatacttaa aaataaaagt attaaattca tttattacac ctccactatg cttttttact
    35161 tcttaattta ttaaatcctg caaataagaa tcctaatgtt aagaatgcac ctggtggtaa
    35221 tataaatatt aatactggtt ggaaagatgc tccaaataat gtcattccaa ataaactacc
    35281 atttccaagt aattctctta ctgcacctat tattgtaagt gcaacagtaa atccaagacc
    35341 ttgacctaca ccatcaacta ttgaaggcat agctcctgtt ttgaaagcaa aactttctgc
    35401 acgagctaat attaaacagt taacaactat taatggtata tatataccaa gagccttatc
    35461 aagagcagga acatatgctt ttaaaagcat acctactatt gtaacaaatg tagctataac
    35521 tactataaat ataggtattc ttatcttatc tggtgtaatt tttcttatta aagatataac
    35581 taaatttgca catattaaaa ctgctgctgt tgaaagaccc ataccaattc catttattgc
    35641 tgaagttgta acggctagtg ttggacacat acctataact tgaacaaatg ttgggttctc
    35701 atctattagc ccatttttaa atactttagc taaattcata attaaccctc cttatttatt
    35761 aagagcacta ttgaaaacat ctatagcagc atttactcct gtagtaactg ctgtagatgt
    35821 aatagttgca cctgatattg ctaatatttg attatctgct gttgtacttc cttttgctac
    35881 ttcaagaggc tcagcagttt ttcctttgta ttgaccctta aatgcatcat ccttagcttt
    35941 tgctccaaga cctgctgttt ctgacatatt accaatgtca acacctgtaa cttgaccttc
    36001 agatgatata cctaccataa cttcaatttc tccaccatat ccacttggtt tagcttttaa
    36061 agtatatcca accacttcag aaccatctaa accttcatac acttcagcta taataccatc
    36121 tccaaggcct ttgtaagtat cttccttcat ttctttaaat tcttttgctt ctggaaggac
    36181 tgcttttcta agttcattat ttgcttgtat atttctttgt tctattactg gagctgtaac
    36241 ctgattagta gctccaagag ctaatgcagc tattgcactt atagcaagta aagtaccacc
    36301 taatctcacc atactgttca ttatttagcc acctccccaa atactctatt tctaacaaac
    36361 ttatctataa gtggagcaag acagttcact aatagtattg agtaagatac accttctgga
    36421 tatccaccat acattcttat aacagttgtt ataagaccag ctaatacagc gtatattatt
    36481 tgaccttttt tagtcatagg cgaagttgta taatccgtaa gcatgaagaa tccacctaac
    36541 ataagtcctc cagcaaacag ttgatatatt gcgaaagtta tattaaatcc acctaaaagg
    36601 aatgttaata taaatacagt tgctatgtaa aatactggta taacataatt tattatgcct
    36661 ttatacatta ggtatactcc acctaataat aataatattg ctgatgtctc acctatacat
    36721 ccaccaatat tccctatcat catgtcagca agactaattc cattgctaga aaggtctgcc
    36781 agtcctgctg ctccattttt caaaaagctt aatggagttg ctgtagtaac tgcatctaaa
    36841 tttttaccta tccagttaac acctggttga gtccaagcag tcattgctac tgggaatgat
    36901 gctaataaaa atgctcttgc agcaagtgct ggattgacaa agttacatcc aattccacca
    36961 aataccattt taactactaa tattgcaaat attcctccta ctagacacat ccaccaagga
    37021 agtgatgctg gtacgttaaa tgctaataat aatcctgtta caacagctga aaaatctcct
    37081 atagtacttt tttgcttcgt aaatttttga tataaaaatt cagtacctac tgtaccaagt
    37141 atacaaaaaa acatagcact caaagcatta agtctaaaga agtatactcc tgctactgct
    37201 gctggaagga gtgctataat aacttgtttc attatatatg aagtatcttc attacttctc
    37261 acatgaggag aagatgatac tatcaactta ttttccatcg tttttccccc ttaactttct
    37321 ttatttctga gcagcttgct ttcttctctt tgctcctatt tctctctttg ctgatcttat
    37381 agattgaagt aatggtcttc ttgctggaca aataaatgag caagacccac attctataca
    37441 atccattgct ctatgatatt cagctgtgtc atagtcatct tttaaagaat atgcacttat
    37501 gaaaagtggt tgtaagaatg atggacatac atctgtacat cttccacatc ttaaacagtt
    37561 ttgaatatct ggagtacgtg attcttcctc atccaaacat aaaattcctg aagaaccttt
    37621 gttagtcgct atttcagtag tatattgagc tattcccatc ataggtccac ccattataac
    37681 cttaccaatc ttcttatctt ctttaaatcc accacattgt tctattattt ctgaaactaa
    37741 tgttccaact tttgttatta ggttctttgg ctctttgatg caactacctg ttattgtagt
    37801 gattctttca accaaaggca tacctgtttt aatagactta gctatctgtg ctgctgtggc
    37861 aacgttgtca acaactgcac ctgctgctat tggtaatcca ccagatggaa cttctttgcc
    37921 tgtacacgca taaataagtt gtttctctgc tccttgtgga tatttcactt gaaggccaac
    37981 aacttcgatt tcgctatagt ctttagctac attttgaatt gcttctatag catctggttt
    38041 attcgtttca attcctataa atcctttttt gacatctaat accttcatta atgctcttaa
    38101 accaaacaca acatcttctg gattttcaac cattaatctg tggtctgcag ttaagtatgg
    38161 ttcacattct gcaccattta atataactac ttctgccttg ctatctggtg gaggagatac
    38221 ttttacatgg ttagggaatg tagctccacc catacctact attcctgcct cttttatgat
    38281 acctactata tcttctttgc tcaaatcctc taactgacct tttggttgaa cactctcatg
    38341 taattcttcc ttaaagtcat tttcgataac tacacattga gctgaacctc ctggtacttc
    38401 atgttgttca atagcaataa ctttacctga tactgaagaa tgaacgttac atgaaacaaa
    38461 accttgttgt tcacctattt tttgcccaaa ctttacttca tcaccaactt caacaatagg
    38521 tttagctggt gcccctatat gttgctgaag aggaatgtaa actatctttg gagcttgagc
    38581 tttttcaagt gcctttgtgt tagagtactc ttttctatat ggaggatgta tccctccctt
    38641 aaaagttaag agtttcattg ttttaccccc ttatctataa aaaaacattt tttctgcctt
    38701 ctataagtat actatatata ttaaaaaatc ttaacaattg ttaaaaaaat atccgtattt
    38761 ttataattta ttttataaat caatacctct atattaagtc aaaccgagga aaaggattgc
    38821 ttaattaaac aatccttttc atatagcttt ctaaagtcca aattttctgt attttatttt
    38881 atagaattta taaacataga gtactcctgc atggatgata aaagcagact tttacttaca
    38941 ctatattttt cttcatttgc tgcttttgaa gctgtatcaa ttttttcatt cacattcttt
    39001 acatactcta ttaaattatc tttaaataaa cgcatttcag aatagtcaat cttttcagct
    39061 tcttttgata tattttgtga tattgccttt ctatttgtca aaatagtatt atatttttcc
    39121 atatctacat tattttcagc attcgaccaa aaacttgatt cttctttaaa gtttgttatt
    39181 aatttattta attctttaga tatactctct atataagcgt agttactggt atactctaaa
    39241 gacaacatag gtgcatctaa gtgtgataaa aatgcatctg gaaacacctt tcttacactg
    39301 cttatctgct ttctaacatc attttcatca aaagaggaat aggtctgtat tttttttact
    39361 ccatccttct ccataactga aaaaggtatg tcattattaa ctaatgatgt ctgtattttt
    39421 ttcaaatcat cattattatc tattgcagca acttgaatag tgtacatatc ccagccttct
    39481 atagtagcta atttgacttc ttctggctct ttagtgttat ttactgcttt ttctggatta
    39541 gtttcttgtt tatcatctga attggtttgt gatttagatt ttttcccttt ttttattgaa
    39601 tttaattcat cagatatatc tttataagtt atatctgatg aattatttag aaatggtatt
    39661 ttagccgata catactccaa tatcttgcta tcttttattt ttgtataaga ataatagcca
    39721 attagacaca agcaagcaat cgttataaca tatttacgta aatcaatctt atgtctatta
    39781 ttattaaatc ctctgtatat cgtttttctt ctattcatta gtttgtccct cccaaaatta
    39841 tattattaat aaagtatatt tttaagagtc acaatttatg aatataaata attatttctt
    39901 ctaatttttt aataagaaat tgtacttact aaacaaatct tcttgcacca agtaatactt
    39961 tagaccaata tgaactagtt aaattatcca ctttaacctt attaggatta gtctgagtac
    40021 cactacaatg gataaattta ctatttccta catatatacc tacatgatta gttgttccat
    40081 caccatcagt gtcaaaataa actaaatctc ctggtgcata attccccata gaaattgcac
    40141 ttccaaaatt agcctgttct ctagaaactc taggaataga aacgcctaca gaatgtttaa
    40201 aaacatactg tgtaaatcca gaacagtcaa atttatcagg tcctgaagct ccccattgat
    40261 atggtattcc aataagcgta tatgcaaaat ctacgattgt tgaacctttt gctgtagatt
    40321 tatctgaatt tccagtaaat gatggctttg agttactatt agattgagaa ttttggttag
    40381 atgatgaatt tggtttttct tttgtatcct cattagtctc agaaatataa ctggcactca
    40441 cccatccaat tgttccactc gataacttta ccttatacca accattactt ttagctttta
    40501 attcaacaac atctccacca tttaattttc ctattataga atagcttgtc ccaggaccac
    40561 ttcttacatt taaactcaca gcagatgtta ccttaccatt cttgccttca attgattctt
    40621 cgctagatgg ttttttatca gaattattag tactatttga attactagaa ttattcgttc
    40681 caacatcctc tgatgtttta gagatatatt ggctactagc ccatccagta actccatttg
    40741 atagttttat tttataccat ccattgcttt gttctagtaa ctttactaca tctccattat
    40801 ttgctttacc aactaatgaa tagttagtac ctgcgccact tcttacattc agtctagaac
    40861 tcacatttac tttaccattt ccactaatag ttgtcccact tgaagttgaa ttattttgac
    40921 ttgatgtacc ttcagacgaa ccacttgttg atatgtattt tgcacttccc catccaacaa
    40981 cagaactcga tacccttact ttataccatc cattagactt ttctaaaatc tctacagttt
    41041 ttcccttgta taattttgct accttatcgc aatcagaact tggtccactt cttatattca
    41101 aggcacttgc tgttactgtt cccttttcaa gagcacttgc atttatggag ctaacagata
    41161 ctgctactgc cccaattcct aaagctgcta tagctttttt cactactatc actcccccca
    41221 acaaattttt atagtcataa attcataaca ttattatcca tttttagtcc ctacaattta
    41281 atgataactt attttcttat taattgtaaa gaaattataa acatatcctt aaaattagtg
    41341 atttttagga agtatttcaa tccaataatt atctgggtcc gctataaaat aaattcccat
    41401 actttcattt tcaaaacata tgcaatctaa atctttatga agtttttttg cctcatcaaa
    41461 ctcctcaact tctaaagcca gatgaaattc attgtctcct aaattatatg gtctatccca
    41521 atctctaagc caagttaatt ctaatgtatg actagtaatg ccatctccta aataaactaa
    41581 tataaaactt ccatcttctg cttccttgcg ctttacctct ttaagcccta aagctttttt
    41641 ataaaaatct aaactttttt ctaagttagt aacattgaaa ttgttatggc aaaaattaaa
    41701 cttcattttg aaatcactct ccaattttta ttttttttat attatatcat tattataaat
    41761 ttatttaaat catattaagt taaaaatttg aatgatgatg aacaattacc aaatcatggt
    41821 aaattattta aaaaaatatg tcaaaaaaag aataagctct ttcaaatgca taaaaaattt
    41881 atacccaagt tatacttaat catgcaaatt ggcagaactt attctttaaa actctaactt
    41941 ttaagttttt ctttgataat ataatttatt actttttttc taatatcttc agcattataa
    42001 tcatcttcta cttctatatc caaaagtttt gctattgacc tcatatcttc tctagtcttt
    42061 gacctatagc ttgatattaa ttcatctttt attttctctg gttctaaaag atattcttca
    42121 tctcctcttt tgaaaacaac gtatttttga gcatatgaac ttctattgta gtatatatat
    42181 cttgatattt ttcttaaaat ttgattatat gaaagtcgct tgttaatatc aagttttaag
    42241 tactctgaaa aagcaaatag ctcttttttt gatttaaata atgcttcttt ctttatagtc
    42301 cttgatattg aagttacact ttcttgatat gcacactttt ttaacatttt taaatatact
    42361 ctattaagac caatactttg attgaatttt tttatattat tattaataat cttatccaag
    42421 ttaccttcaa agtatttttt tgctcctttt tgtgatacat aactctcaag ttctttgtgg
    42481 gccatatcaa gtatcatttt ttttaaatcc tctttatatc ccctagattc catgatactc
    42541 cctcccttag ctatttatag tatattcaaa aagctcaaga aatgtgagtc attacaaaat
    42601 ttttttactt tttatgtata tattaattta aaaggggaga taatagtaat gtaaaatcaa
    42661 acatactcaa tctcccccat ttttagacct ctattactcc cccaatagag gtcttttttt
    42721 agtttatcaa tttctattca attcccttta gttcaaatcc taattctgct atcacttctt
    42781 ttaatttttc aatagataca tcatctttca tatctacaga tgcacactta ttttctaaat
    42841 ctacatctaa aacttcaata ccatctatat cttctgttaa tgcagtttta agatggttta
    42901 cacaatgacc acaactcata ccttctacta atagtttctt cttcatttaa ttacctcctt
    42961 ataccctata agggtattct atcatatagt ttatactttt taaatagaaa ttaatcattt
    43021 aatttgattc attcgatttt atatctaaat tagatattcc ctcatataca tcaaaatcat
    43081 ttggagtaat tttacctttt aatctactat tacttacaat atagttgttt ctgacagcta
    43141 aacttataaa tgttgcatta tcttttatat atgtctgtac atctttgtat gctttttttg
    43201 tttcaatttc agacgtagaa cttgtaagtg cagacatata tccatttaac ttatcatcag
    43261 tatatccact actcgctata atactacttg catctggtat aattgatagt ttccatccaa
    43321 ctaatgctaa atcataattt ttagaattaa gagcattttc catatcctta tctgacagct
    43381 gatttactgt actatttatt cctatggctt ttaagttttc atttattatg tttgcagttt
    43441 ttattctctc actattatct ctgtttacta ttatctttaa gttcatttca gaaagacttt
    43501 tctttacttc ctctttttct ctattttttt tctcttcagc ttcttttttg attctatctt
    43561 cttctgcttt tttagctttt gcttcttctt ctggcgtaag cttctttgag ttctttttag
    43621 ctgatttttt ctgatttttt actttattgt cattttgatt tactgagttt acatttgcat
    43681 attctacctt agcaagacac tctatcgcct tatctttatt aaactctaaa tccttcattt
    43741 cactattata gtattttgat tttgaattaa gtggaaaatt aactggagta gcatcatcca
    43801 tataaccttc actaataatt ctatctttat ctatagagtg tgcaattgct tttctaaaat
    43861 taacatcttt gaaaaaagga ttattataat taaataatac acactcataa tctcttcctt
    43921 gatattttgt tatattaaac tctttttctt gaaacttact taaatcattt aatgtaacat
    43981 tggttatatc actatcaaga gccataacca tagatgtcct tgcatcttca ttaggcacca
    44041 tacctacttt tatgttcttc atggtctttg gaacttcttc atagtaatct ttgtttacag
    44101 ataaaaccat tccttctctt tctgtatatg attctatttt atatttccca tttcctatca
    44161 tattattatt cttgtcattt acatcttttg aatctaaatg attttgagat acaattggaa
    44221 aaattaaact atcaattgaa aaagcatatc tagctttaaa ttttattgta aaatctttat
    44281 ctgatttaat attcacagaa gctatatttt tagtaaattc attatatgga ctatctgcac
    44341 ttttttgaat taaaccaata gtatagttta catcatttga agtaacattt tttccatcat
    44401 gccactttgc atcttttagc tttatatcta tactcattcc atcctgagct atattatact
    44461 ccttaactaa ttgaggaatt acattgtagt tctcatctat agtaaataaa ctatcataaa
    44521 ctaaattcat tatataacca acagacttat cagtattagt tataggattt atagtttttg
    44581 gagttaccat tgttaagttt atatacttag catctataga actttgactt tgtaaacttg
    44641 aatcactact actttgtttt gttttagtat tactacaacc agctaccata agagttatag
    44701 ctaaaacgac tgttaagact tttattctct tcattagttt tttcctttct tgccatatat
    44761 cttattataa tgttcgtaat tattttttac tttttctaca tattttgaag tttgcttaaa
    44821 aggtatatca tgtagatttt cgccatcttt actatattca ttattttcta accatttttt
    44881 cacattacct gaaccaccat tatatgcagc tatcactaaa tctaatttac caaattcttt
    44941 gtataactta cttaaatacc aacagccaag tcttatatta gtctctgggt cgaaaatatc
    45001 cacatttttt aaatttagtt cctctgctcc ccaatctcta gttatgtcta atatttgcat
    45061 taatcctttt gcttcctttt ttgaaacagc agaactatta aacttacttt cggctttaat
    45121 aacactgtaa actatatttt catctaaatt aaattctttc gaatactttt ctacatactc
    45181 tgaatatttt ttaggatata aaaatttatg tattactttg ctttccatta atagtgcccc
    45241 aaataagatt ataaaaatag atagaatcaa tactttctta ctattcacgc caattctcct
    45301 tcatgtactc aataaattta tgtgctttac tttctaattc agttattgtt cccgaattat
    45361 ctattatata atcaccatat ttggattttt cttcctgact catctgtgaa tttatcctac
    45421 taagtgcttc ctgctcactg caattatctc tcttttgtat tctactaatt tgtacttctt
    45481 gtttacaagt aactactaat agcttgtcaa ccatatctaa aaaaccactt tctaccaata
    45541 ttgccgcatc taacactact atattttcgc ctttttttct caatttttct atttcactta
    45601 ttattttttc tcttattcgt ggatgagtca agttatttaa ttccttaagt ttttcttcat
    45661 cactaaaaac tattttccca agagcttttc tatttagagt tccatcatca ttttttatac
    45721 tttgcccaaa atggacaaat actttttcca ataacaactt atcctcaaat atcttcctgg
    45781 atataatatc agcatccact ataggaatgt taagatttct aaatatattt gataggctgc
    45841 tttttccaca gcctattcct cctgtaagtc ctaatatcaa cataaaatca cctactttgt
    45901 ctcataccaa gaactaccta catttaaatc tacatctaag tgaacatcca tatttacagc
    45961 attttccatt tcttctttta ctattttctt aactatatct atttcatcat caattgcttc
    46021 aactatcaac tcgtcgtgaa cttgtagtat aagttttgat ttcaaattgt tctcttccaa
    46081 ttttttatga acatttatca tagcaatttt tattatatct gctgcacttc cttgtattgg
    46141 tgcattcatt gcaaatctct ttcctctatt tctttccata aaattgcttg actttatttc
    46201 tggtatatat cttcttctgt ttaaaattgt tacagcatat ccatcctcac tagccttttc
    46261 tactgttgtg tccataaact cttttatttt atggtattta gcaaaataac tttcgatata
    46321 ttctttcgcc tttggaacag gtatatttaa atcatcagct agaccaaagt cacttttacc
    46381 atatataata ccaaagttta cagctttagc tgcacctctc aattcactag taacatcttc
    46441 cataggaaca ttaaaaactt gtgaagctgt tttggtatga atatcttcat gatgtttaaa
    46501 tgcttctatc atattttcat cctgactcat atgtgcaaga actcttagct ctacttgtga
    46561 gtaatcggca tcaaccaact tacagttatc atctgcaata aacacttttc ttatttttct
    46621 acccatttcc atttttatag gtatattttg aagatttggt tctgtagatg aaattcttcc
    46681 tgtagtcgtt atagtttgat taaatgatga atgtattcta ttactttctg gatttattat
    46741 atttaaaagt ccttcaacgt aagtagaatt taactttact atttgtctat actcagttat
    46801 cttatctatt attggatgct tatctcttaa tttttctaaa acatctgcat tagttgaata
    46861 tccagtttta gtttttttaa ttattggaag ctctaatttt tcaaataata taacacccaa
    46921 ttgttttggt gaatttatat tgaatggctc tcctgataat tcataaattt ccttttctag
    46981 tgtagctatt atttctttaa attcaacact caattcatcc aatatacttt tgtctacttt
    47041 tataccttca tactccatat gacctaagac ttctactaaa ggcatctcta catgataaaa
    47101 aagaccatcc atactcatat ccattagact tctttccatc ataggaactg tttctttaac
    47161 tgtgcatatt atttgaccca tatactctgc taaatcctca aattctaaat cctcatagtt
    47221 tttagattta acaccctttc ctaataattc ttcttttgat ttaacctttt ttgataaata
    47281 cttcatagct attgcactac aatcatatga ggtagatgaa gttgaatcta ttaagtactc
    47341 agctattgtt atatcaaaat acatattttc taagtttata ttatatggtt ttaaagatat
    47401 ataatcatct tttaaattat atccatactt tttaatttca ttatttgaaa atatactatc
    47461 taactttgac acttcatttg aatctacata atatattttt tctccatcta cacttataaa
    47521 aatatatatt atattttttt caagtatatt accttgtcct ctaacagttt ttaaaataac
    47581 ttgtcctttt ttgtttactt catctataaa tttttctgta tcttttaatt ttaatatttc
    47641 tattttttct tctatgtgtt ctgtgtcatc tgaatcgacc aaatcaacta atcttgataa
    47701 gagacttgta aatccaaagt atctaaattt atctaaaagt tcatctttat cataatcgcc
    47761 aaaaatcata ctatctaaat ccacttctat tggcacatct cttataattg ttgcaagtct
    47821 tttactttga atagctattt ctttattttc ctctattttc ttttttacac tacctttaag
    47881 tttatctgta ttctctatta aattctctat actagaaaac tcttttataa gctttatacc
    47941 tgttttttca cctattccag gtactccagg tatattatca gacttgtctc ccataagacc
    48001 ctttaaatcg ataaattgtg ttggagtcat ctcatatttt tcaattacag aattaaagtt
    48061 gtattcttct acttctccaa cccctttttt cgttataaga gtagttgtat tatctgaagc
    48121 aagttgaata gcatctttat ctccagttac tatgtatacc ttatatccat tttcttctgc
    48181 ttttttagaa acagtaccta taatatcatc tgcctcataa ccatctattt ccaatctatt
    48241 tattttgaat ttatctaaaa ggtcttttaa tggctgtaat tgttctgcca attcgtctgg
    48301 catacccttt cttccagcct tataatcttt atattctaaa tgcctaaatg taggtgcttt
    48361 tctgtcaaaa gctacactta tatgtgttgg tttatatata tctatcattt taaataacat
    48421 tgtagtaaac ccatatatag cattggtctt taacccttct ttattattca tttctggaag
    48481 agcataaaaa gctctattta ttattgaatt tccatctatt ataattaatt ttttttccaa
    48541 attatatcac tcctaaaaat tatctatttt tgtaacatat atattatata ccaatatagt
    48601 gttatttaat attcccataa taataatagt atattaaaat taaatatgtt gcaaacaata
    48661 tatttttttg ctataataat atacatgaca tgcccgagtg gtggaattgg tagacgcagt
    48721 ggactcaaaa tccaccggac taatactccg tgccggttcg agtccggcct cgggcaccat
    48781 taaaaactcc taaagctatt tattcaatag attaggagtt tttttatttt tgatttaaat
    48841 tttaagttat tttttgaaat tactgtgtct ttttaaaatt tatataatta tataaattta
    48901 tcttctagca ttaatttaaa aactaattta cttttatata attttctatt ttatatcata
    48961 acttattaca accttttatc taatttattg tatacaacaa cactacaaat aaattgaaat
    49021 aaaataagca atccaagaac aactaaaacc cacttgctta ttaccattac agaaaataca
    49081 ctcaatatag aaacaataaa tataagaatt acaagaacat agcacataat ttgattagta
    49141 atacgtccag ctttatcacg taacataatt cttctttcat cattcatctc tatcctttga
    49201 ttttttatct tttcttcata atctactgct ctttcaggtt tactccaata catatattga
    49261 agaatcatac atacacctgg acctaaagca gctccagata atccccaaat aaaagcctca
    49321 aatgaaaact cagtaaatgt agccaataaa acaagtaaaa ttccacaaat aaaatatata
    49381 attccaacat ataacatatt ctttttcatt tttactcctc ctcataaata aatatttctt
    49441 caatactcat atcaaagtat ctagctatct taaaggctaa gatgatagaa ggattatacc
    49501 taccattttc taatgaacct atagtttgtc ttgatacttg caaaatagaa gcaagttctt
    49561 cttgttttat gcctctttct tttcttattt cttctaatct atttttcaca tctatccccc
    49621 tttaatatct caactacgga aagtctactt tccataatta tacaactata ttccatttat
    49681 gtaaagctta ctttccatat ttacaaaaaa ataacagact attttcagcc tgtaatttta
    49741 gaatttcata ttgtttatta attttaatgt tatttattaa ttccatatta tttattaatt
    49801 ttaacttggt ttctgaattg gaatccaaac ttctgtagta taatcaggag cattgatatc
    49861 gccattggga taaagttcaa tatctggtaa attagcatac acatacccag aacttggtaa
    49921 ccactcagta ataattcttt tttgcaattc ctgtattgcc agagcatttg gcattggaga
    49981 aacacattca aatactgccc atgtgcctga tggtattaag tattcatgag tatcttctaa
    50041 tacaggctta tctgttggag cagcaatata ataatctaaa cccttactat ttgtacacac
    50101 actaactcca agcaatccac aaggttcgtt atttattaac tctgaaagtt tatcaattgt
    50161 tccatttttt atgcatttag cccataactt aggaactttc tcaaaacact cttctacaat
    50221 catgttcata ctttctttta taccaacaat acgaaaccct ttcttttcta caatacgata
    50281 ttgcatttct atatttcctt ttacataaat gcttaatgtc atcttaggat atgcttttaa
    50341 aacaacaccc tttgctctag ctgcagatgg agaaatgtta tgtatatttt gaaaagctct
    50401 attaaaagat gttggtgaat cgtaaccata cttctcagat agttctaaaa ttttgatgtt
    50461 actgttctga agttcaaatg cagccttagt catacgtctt cgtctaatat attcagataa
    50521 tggtacttct gcaatatatg aaaacattct ttgaaaatga aaggttgaac aacatgcaat
    50581 ttttgctgct tctgcataat ccactccact ttcgagattt tcttcaatat aagtaatagc
    50641 ttgatttaat ttatttatcc attccatttg atattacctc caagcaaatt atacagttta
    50701 ataaaataat atacctctct attcatgcac aaaattgtaa gcatttaaat ttataagcat
    50761 ttttcaatca atacaataaa tataaaaatt gtattataca ataaaaaagt tcaataacat
    50821 tatattgtaa aatgttattg aactttttat aaaaattaat ttaagtgtag ttaaattaag
    50881 tattacacta tcttatatat tacaatatcc tactatctta tagtcttctg gcactttata
    50941 atctttgtct ggagtaccta aattccattt taaatcaaac atagttgcac ttattattgt
    51001 tgcaaaataa agcataacta taccaatgtc tattttttct tcatataaat tagtatgacc
    51061 atcttttcta acagctaaaa ctacagtgcc tccatcaact ataaatctcc atggttgtct
    51121 atttaatgta gatggagcta atcttgcata gtgaaatgca tcaagaagtg ctctttcttc
    51181 taagatttct atacttgcaa catttcccca ttcgttcata taaacaacat cttctacacc
    51241 tagtctagta gaccccttat ctgttacaac ttgcatatca gattttgaat aattttgccc
    51301 agtttttgta gcatttaata ctttagcatt acttacattt tctccatatc caatagctat
    51361 aattcctgtt acctctttat ctgaattaat tccaagtttt tcttttacct tttttccatc
    51421 ttcaaaagta acccaacaag aaccaattcc aagttctgtt actttaaaga ttatactttc
    51481 tcctatgtac cctgaatttt caatgtaatt atcttttatg tcagataata ttataatata
    51541 acttggagaa tctatcatat ttcctttgta ccctgctact ttatctaaat tattaaaaac
    51601 ttcacttcta ttcataattc ttacatcaac atctatttct ggaactagtt tcttacaaga
    51661 ttctgagtat ttcttaattt cactaagata ttcttcttta atatctgtgt tcttatattc
    51721 tctaacagac tttctattta atatgattgt tttataatcc ataattttat cctccccaaa
    51781 ctagtattgt tttaattata tacccattaa tatattattt tactcattta tttaataaat
    51841 aaagattaca attttgtaat tattatttat taataatatt ccacttttac attaataatg
    51901 accagttgtg caaaatccat tgccaaccac caaataaaaa catattataa aggtaatata
    51961 aaataacaaa caaatcttaa caaaaaatta aacttttttt acacgaaaga aggcttcccg
    52021 ttgccttctt tatttttata aaaaaataag ctgtttctaa aatgatttca catttttgaa
    52081 acagccaagt tattctataa tgacaactat aatttgagga tgtgagggag agttgtcatt
    52141 ataaatttag ggtaattata ttatgtttta agctagttct ttctatattt atataataca
    52201 ttttatatat gaattttata tgagattggt ataaatgata tatgaaatta catatgttta
    52261 tattatatta aattttatta ttacattttc cacaacaata ctcatatgtc tccacattat
    52321 ttggaatatt tacaaataca aattctttac agttctcaca atactttaat atagatatag
    52381 ttccacaagt gtaacattca aatattacac aatcctcatt ttcctctact atttcaaact
    52441 ttttactatg ttcaccacac tctgggcact tgtgattatt tacattcata aatactcctc
    52501 cttattagta tagttacatg tcaaaaactt aattaatgta ttctatatta cttattatat
    52561 attctataat aaatcatatt ctaatataat aaaacaaatt aaataaaaaa aaaccataaa
    52621 ttttaaattt atggattaat tcttgtaatg ataactctat ttgaggatgt gagggagggt
    52681 tatcattaca atagggtatt atattatggt ttttaagcta gtctttctac acctcatatg
    52741 atacatatgc tatatgaatt ttatatgatt tttacataaa tattttatga aatttaaatt
    52801 ttttagtaat tttgaaattt gtaaaaagtt ctctaaaaat ccacagcatc ataaacagcc
    52861 aaaatttaag tagaacatca taaaaaaatt tgtccaataa ttttaacaag taatctcacc
    52921 tcatcataat tattgacaca aacttaaata aacaatctat aaatcttcta taaatcttaa
    52981 actttccccc tattgataca caatttctag tttgtcaatt ttattttgca tttctaagaa
    53041 aatttcttca acagaattgt taaatatatt gcctaaatag attcttttat ctttttgaaa
    53101 tgaataagat tttacactac catcagaaga aatatataaa tgactccact ctgctccata
    53161 ttttgaaaac ctctcctttg tatctttaaa cctcatatct tctattttta ttgctttttc
    53221 tctgtctcct cttactacag tgtgacccct ttttattaaa ctggttattt ttatatcttc
    53281 ttttaattta atacgtgtat catcattttt tgaatatact ttccatatca ctttatgacg
    53341 ataattatct aattccttta ttaagcttct atcaatagta aaactatctt tagttaccac
    53401 aattaaatca aaatggtcta acatatattg aaatatttct ctcatacttt tattttttaa
    53461 aatatcctca ccaataacct ctataaatct acagcctttc tcatacatgc agttcaataa
    53521 acttgtgatt tcagaaaaat aatcatttgt attattatct ccatctattt ctatagtaaa
    53581 gtacaaagga gtaatgtatg atttatttcc tgttatctca aatacacttg atagtgtctg
    53641 tatatcatct tcaaacgtta agtatacatt ctcataaaac ataaaaaatt ccataacttt
    53701 ttctttcata ttatggatat ttctatatct attggataat atatttatta tatcgtcagt
    53761 agtatttttc ccatcacatt cagccagtat aacaatttgc ttccaactta agctatccac
    53821 atttccgata ctttttttat atccatcttc ttcatcataa atagggccaa ttataatgtt
    53881 ttcttttggc cacagatgaa ccctagttcc atcttttaat ttcggatatt tattttttac
    53941 agactcataa aatctacttg tatcacccat gattctttac taccccccat agtttaaata
    54001 ttctatgcta aaaatagcac tttattttta ttaattcaac aattattcaa aattggtcat
    54061 tatatatgtt taaatggatt taacatcaac cttatttata tgttattgat gtttatatat
    54121 gttatataaa atcttatttc tcatacttca atgtaatctt aactatctct ggtttacaat
    54181 taagcctaat taaaactttt gagcctccta agcctttatt taaaatcata gtgctattat
    54241 ctttttcata ttttccccag tcatacttag gaaagaactc tctatttgga gataatacac
    54301 ctccaacaaa aggtattctt attatacctc catgaacatg tcctgctaaa accaaatctg
    54361 ctccccattt tgcatatttt tcaaagaaaa atggtgtatg tgctaaaaga atgttatatt
    54421 cattttcatt aactttacct agattgtctt ctacaaaatt gtcacttagt tctaattttt
    54481 tgttattagc aaataaatat ggatagcatt ccaatggtat aattaaacca tataaattaa
    54541 gatggctatt acctctatat attcttacag attcattttc catatttatt attttctttg
    54601 aatatagttc cttaaaataa tccttatata gatgtttata cttttttatt aaagattttt
    54661 gttcatgatt tccaattata tgatatactt catatttttc aaccaaatta tctattaaat
    54721 ctaatgcaac ttgaaaattt ttattttctc catctactaa atctcctgtt ataaatataa
    54781 catctgggtt taatgattca attttatcta tcaatacctt attattttta tcaaacacct
    54841 tattatgtaa atcactcact tgaactattt taaagttatc aaattccttt ggaatttttt
    54901 tgttgaaaat agtatattct gtcgtttcta tatgctgagt ttcatactta tacagaatat
    54961 acaataatat taatactaat actgtcattg aaacctttat aatcatattc tcttcctctt
    55021 tattctattt tgttaatatt attataatgc ttttatgttt tttttaaaac aataacatca
    55081 tcacatacat ataaatcttt tcgacattat aaaaataagt tatccttttc taaaattttc
    55141 atttatttta gaaaaggata actataaaat tatctataaa cctctatatt gtgaaatata
    55201 gtttttcctt tatttaaatt tttatatata tgctctaaag ttccatcaaa cctaatagaa
    55261 tgtccagact ctaaaatata agttttccca tccacattaa ggtcaagttt accttctatt
    55321 acgagcacat attcttctaa aacatgacta tgtgtagatg aaacatgagt acagttttcc
    55381 tcaagctcaa ttataaaaag ttcaaacctt ctttgagggc taaaagggta tattggatat
    55441 aacttcatgt tccctttttg ctcaacaata ggctctactt cttctttctt tataacctca
    55501 taggtatttg tattttcatt taatagtgta gtaaaattta ttttaaatcc agatgaaatt
    55561 ttccataaag tagatactgt cggacttgat tcacctctct caatctgtcc aagcattgct
    55621 ttactgacac ctgtcatctt tgaagctttg tctaaactta tgcccatttc ttgtctcaat
    55681 aaccttaaat tttctcccac attaggaaat ttattatcca tgttaaaatc ctcctgatag
    55741 ctatttgtat tctatgattt ttactcctgt aagttctact atctctttta attttaacat
    55801 atgattgtta caaatttcat caaattcata tatataatct tcaagcccta atgccttata
    55861 tttatcgatt ccaaatttat gatatggaag taactccatc ttgcctcctg gaacattttg
    55921 tttgacaaat aatgcagtat ttcttatatt ttcttcacta tcatttactc cataaataat
    55981 tggcactctt ataaccatag atttattcaa ctttgaaagc ctacatatat tatctaatat
    56041 aattttatta cttactcctg tatattcttt atgaatatta tcatccatag attttatatc
    56101 tacaaatatg tggtctattt tctcaaatac atcatttacc ttattccaat caaaatatcc
    56161 acaagtttca attgcaatat ttatgccttt atcataaaaa atatcaacta attctcttaa
    56221 aaaatcaatc tgaagtgtag gttcacctcc agaaaaagtt atccctccat tagattcaaa
    56281 gaaaaatata aaatcttttt caacttcctc tactatttct tcaacactca tttcttcggt
    56341 cattatacaa atggcatctt taagacatac cttgatacac tctccacata aatcacattt
    56401 attatttatt tgcgttctat caaatagtga acttatattt tgaggacaaa catctataca
    56461 tctattacag gatacacatt tatctttcat aacacctaat tttactatgt tactccagga
    56521 atctggatta gaacaccact tacattttaa tttacatcct tctaaaaata tagtagtcct
    56581 tattccatct ccatcattta ctgaaaaatg ttgtactttt acaactctac cttttttact
    56641 cataatctac ctcataatta aaaattgcta tgtgaatttc tagctattat agcatcttgc
    56701 atttctcttg ataaattaac aaattgagta ctatatccag caaccctcac taataaatct
    56761 ttatattctt ctggattttc ttgagctttt aatagagtat catttgatat cgtattaaat
    56821 tgtacatgga atcctcctaa agcaaaatat gatttaatca tagatgttag atttctaagt
    56881 cctctttcag tttccaccaa atcttgattc agtcttaaat ttagaagtgt tccaccagta
    56941 tgaacatcat gatttatttt tgatgcagat ttcattgctg ctagtggact tgttgtatca
    57001 gtaccaacaa atggagaaac tccctctgtc aaaggttttg tcgcttttct tccacaagga
    57061 gttgcaccta cgatttttcc agttggtaca tagtttgata tacccataaa tgcactatta
    57121 aatttagagc caaaaatatc cttgtatttt ctagtttcag tataataaaa atcagaaact
    57181 tcaattgcta atgaatctac ataatcatta tcatttccat acttaggaac atccaacgca
    57241 agttttctta attcttcata accttcccaa tcattattta gtgcttttgt taattcttct
    57301 aacgtagtca ccttatcctc aaatactaat ttttttatag ctgccaatga atttgaaact
    57361 acacctaacc ctataccagt taatacagga cctatattat attttgctcc tcctttactt
    57421 aaatcaactc ccttatccaa acatccatct acacaagtag ataaaaatgg tcttggtacc
    57481 atttctttat gaatttgttg agcaacagta gttcctataa cagaactttt tacaagatat
    57541 gctaattgct ttaaaaactc atccttaagt tcttcaaaag aagtaaattc tgtgatattt
    57601 tttgtatcta accccatttt ttctccagtt aatctactct taccttcatt catagcatat
    57661 tctaaagctg ctgcaaaatt gatatttacg gctgaagtcc actgtcctgt ttttctaaaa
    57721 tgaggaacta cacaaccaca gttactccaa tctctagcat cttctgcatc atatccatct
    57781 tgtaataaca tttgtgcccc tgcactatcg ctgtgtatag cagggaaacc agttccttgt
    57841 tttaccaatt tagcaactgc cattacgaaa ttgtctggtg ctccctgact cactctaaca
    57901 cttaatcctg gctggtgagt ttttacactt tctgtagcct ttaaacacat atatgagata
    57961 tcattcgttc catcagtacc atttctcttt ttaccaccaa cagtaagatt ttggaattga
    58021 ttatatcctg caaagtaatt tgctgtattt gctgatatag tccataccca ttctgataac
    58081 ttaatccaaa gtgcttctat caattcttga gcttctgatt cagttatttt accttctcta
    58141 gcatcatttt cataatatgg atacatatat tggtcaaatc tacctaaatt taatgccaat
    58201 ggattttctg atagaatacc acctaattga acaaaccata caaattgtat tgcttcataa
    58261 aaattagttg gagggtttgc tggtacattc atacatatct ctgaaatttt tataagttct
    58321 aactttctct tttcatctgt ttcttgctta ctcatctctt ttgcaagatt tgaatatctt
    58381 tgtgccaatg tcataatacc ctgtgcaact atagaaacag atttgtaaaa atctatcttt
    58441 tcaatatttt ctgaaactga tatatctaat tctttaattt ttttatctgc atcttcctta
    58501 atccctttat atccttttac aaacaatata tcttgataat ctggtgttac ttcaccaact
    58561 gcctgtctcc acttagaatc attatctatt attcctgtat ctactaatat cttagctgta
    58621 tcttctggga ttcttgctaa gaaaacttct tccaaagatt ttcccttcca atatggaaat
    58681 atttcttttc ttataaattc tatttgttct tttgatatta catatgggtc ttgagttctt
    58741 ttatcaaaag tatccatttc tttgtctacc cattgccaag aaaactctgg tgtcaatatc
    58801 cctgttcttc taaattttcc tgctgtacct actattaatt cattttcaaa gatttttata
    58861 ggaagttctt tacatgtctc caaaaaagct ttagctcttc ttatacagat agcttctccc
    58921 tcagtttttt tatgtgattc tgtaaaaatt ctagcccttt cacaacatat cataggttta
    58981 gaattaatat attcttgtct aaatgcttct attctattag tttgactcat ttaaaatccc
    59041 cctttggata atatatacta catttttgta tgttataaca tactttaatt atattatact
    59101 gtcctttagc ataaaatgga agcaaaataa cttatttttt ttcatctacc ttgaacacct
    59161 atatattaat actttttttg ttaaatttat aaactctaaa aaaattttct atgatatatt
    59221 ttctatattg ttatagttat atctaatata ctaatgattt gaaatatcaa atttgtatac
    59281 tagacttagt tttaaaacct tagttgattg tttaactttg ttaacttcaa catgtatatc
    59341 cttcatataa ggaagctcta caacacctac tcccttatta aattcttctt caaccataga
    59401 aaaaatttct ttctcagtta agttcgtatt agtcaatgac ttaaataaat tgtatataaa
    59461 tttaatatat ttatcactct cagataactt atcatcttct ggatactctt tagcacagag
    59521 aatatctatt gttacttttc cttctttatc gtcttcagac atagaataga ataaacttcg
    59581 aatatttttt tcaggtggtt tttcagcacc atttatagat actacaaagc taccatctga
    59641 ttttgagtca gtaatactat aaccactgtc tattatagct ttcgaaaatc tttgagataa
    59701 atcttttttt acttcttctc tacctttcgc atcattaatc ttttgtgagt aattattaaa
    59761 tagctcgata gattcatctt ttttatcttc aacttgttct ttcaatgaat ctttactaat
    59821 ttgttctgag ctacttaagt tcttatcaga tacaggagac atacacccta ccatcaatgc
    59881 taagctaaga tttaaagcca caattattgc cactctattt atattccttt ttactttcat
    59941 acacaatcct cccatcacac taaccgctct aaagtattat tcattgcact agaatatatt
    60001 tatattttct ttatattaaa gatttattat tcaatacata tcaccttcct atccaattct
    60061 tataacttac tattagtaaa attataagct ccttaataca gaaataagga tgttatcttt
    60121 tgttattaaa agataacatc cttatttttt tgtatcaata catatgtccc aactggtaac
    60181 ttaatcgccc caactgtcag tatcttggtc caatggtata tatatattta gtataaattt
    60241 atcgatacta ttttcaaata ataattctcc attatatttt tgtaaagaag atttaatact
    60301 ctgaatacct attccatgta cgaacttatc cattttgttt gttaacaata tatttttatt
    60361 aaaagtaagc tgatttagtt tactattttc acatttaagt acaaaaaatg accttgttat
    60421 agttccttta attctaatat atttattaac attttcatcc actattttat cacatgcttc
    60481 tattgcatta tccaaaatat tagaaaatat gcttgacaca tctataggtt ttacaaaatt
    60541 tacttttgaa aaatttatag agcaagtaaa tttaattcct ttttttaaac atacttcact
    60601 cttttcgttg attataatgt ctaatatcat atttcctgta ttatagatat atttaaatgt
    60661 ttttatttca tcttttaaat tgttaacata ttcattaatt tctttgctat tgtttctaag
    60721 gttgtctata caataaatgt gattatttat atcgtgatat agtttcttaa ctcgcatatg
    60781 agattcttga atacttaaat aatgcgcata ttgcatatct aacttatttt ttattaattc
    60841 agcttgagat tttaatctat tctcttttat tatttcttta aacaatagta taagaaatat
    60901 actactagct cctaccaatt ttggattaac aaaattatca aaatagtatc cttctgaatg
    60961 taatgaccca aaccgttcta atttttttaa tacataattt acaagcatat tcattgtatt
    61021 aactaataag gcaaataata aatatacata atttctctta tcttggctaa ttaattttat
    61081 agactttcta aaaaatctaa atataagata tataagaata attattaaat tactatatat
    61141 ctgaattttt atagattcta agtaaggtac taataaagat tctttagatg aaataacatt
    61201 acctgtaatt gcaaaaaata gtattctata tataacagca tccaaacatt tataatatac
    61261 actaaataga taaaagaaaa tggaatactt aatataaccc atcttataaa aataattata
    61321 gtatcctccc caagcaataa atgctaatat ataaaataaa tagtttatat tactaaagta
    61381 atttcctcca ttaaataatc tacttatctg aattataata taaataagaa acaagacaat
    61441 atagaatact attttttcat tttttttact atccttttta taaattaaaa ttccgttcat
    61501 tatagaaaac tgtataaata tagataaaac tactaatagc tcagtcataa agtttagcat
    61561 attgtatcac caagaaattt taagaatttc tccttaactt ctttatatct atatctacta
    61621 ataggtacct cttctccact ttccagtatt gcagtattag gctttatatt ttcaacatat
    61681 cttaaattta ctataaaact tttatggcat cttataaatt tatatggatt taattctttt
    61741 tctattttgc ctaaactata ttttatatca aaattcttgt ttattgtgtg tattagcata
    61801 tctttttttt gaacttctat atattttatt tcatttaaat aaatcttata tgtattagac
    61861 ttatttttta ttgtaatatg actttcctta tttatttcaa tatctttgat acaagttagc
    61921 acatgttttt ttagttcttc caactctatt ggctttagta aatacctata agctcttacc
    61981 tcataacctt cttgcacata atctattaat gaagttacaa atattatttc catttcattg
    62041 tctacttctc taatctttct tgcagtatcc attccattta atttttccat ttttatatca
    62101 agaagtaata tatctatatc ttttaaatta ctttccagta actcttctcc agatatatac
    62161 ttttgtatct catattctat acttatatct tttaatatat tctcaaggta atcttctatt
    62221 aaaagttgtg tttctttttc atcttcacaa actgctatct taatcataaa atgcctcctt
    62281 acataatttc tagttaatac aattaaaata tttataatat atttaaagat aattttgtat
    62341 atctgatact ttaggataac atttttaaat tatttttatc aatactcaat cccatacaac
    62401 tattatttga tatttcaatt taaagacaga aattactata attaaaaaca gtactttatt
    62461 aacaaaataa gatgtcttaa aatattaaaa aaataatttt aggacacctt cttttattta
    62521 tttaaacttt ttaagcctta aataatacat taatctccta tataattgta ctgcatataa
    62581 aatcaacaat ataatctgta gtacaatagc agttacagat gctccataac cactatataa
    62641 atttcttatt tcaatattca ataaatatat aaatattact actaacataa agaatataaa
    62701 catattcata aataaaattg actttacttt gtttttttta tcagaatcac tatataattt
    62761 aggaggtatg tctttgtatt ctttcgacca tatataccat gcagatgtac ccataaaact
    62821 accaatactc ctaaatacaa gattccagcc atttgattta tgttcatcaa aataattatt
    62881 ctctacatca tagtagtaat caacagtgta ttttattttt cttggacttc ccttatgaaa
    62941 ataaaatatt cctccaaatt tatttatctt atataaatta tatcctttag cttcaatatc
    63001 ttctaaccat ttctctatct tatcaggtga actataccag tcaaatttga attttatttt
    63061 cttttccata gcactcattc tccaaaatga tatttttaaa tagcttaaaa atctatttaa
    63121 ataattatat cattttgata ctaattttag gttacaatca tatatttaaa aagctattta
    63181 aatagtaata aactaatagc cataacaccc attcctgcaa tcaatccata aatagataaa
    63241 tgatgttccc cgtactctct agctgatggc aataattcat ctagtgatat gaataccata
    63301 attcctccta caattgcaaa tacaattcca agagttatat catttaaaaa atttctaaga
    63361 agtacatatc caataatcgc tcctaaaggc tcagacatac cagataaaaa ggaataataa
    63421 aaagctttct ttttatctcc tgtggcataa taaactggta cagatacaga tataccttct
    63481 ggtatattgt gtattgcaat tgcaattgct atcggaatag ctattgtaac atcatcaaga
    63541 gctgatataa atgtagctaa tccttcagga aaattgtgaa ttgctatagc cattgctgta
    63601 aatatacctg ttcttaaaag agacttattt tttttgatat tcttttcttc tatattctcc
    63661 attttcttta tttcatgtgg attttcttct tgtggaatta gcttatcaat aacagcaatg
    63721 atagccatac ctataaaaaa agctattaca gttgaccaac ttcctaattt ctctcccata
    63781 gattttgtca aagcatcttg tgctttagga aaaatttcta tcatagaaac ataaatcata
    63841 acaccagcag aaaatcctaa gcttatagaa agaaacttag tatttgtttt tttagcaaaa
    63901 aatgctatac aacttcctat accagtagat aaaccagcca ataatgttat caaaaatgca
    63961 aatattacat tattcaaata aatcaccttc tttttaattg atattgatta tcattttctt
    64021 tatgctatca tatatatttt atatagtcaa tatttataaa aaatatacac aataaaaaag
    64081 cagagatata aacttagtct ctgctttttc tttatagtat attaaaatta tttatttaag
    64141 aaatccactg catattgcac atataaagca gttccaattt ctagagcatc ttcatctata
    64201 ttaaagcatc catgatgatg aggataacaa gcaccttttg actcatttct agctcctaca
    64261 aatgctagtg caccaggtgc tatattcata aactcagcta aatcttctgc tcctgttact
    64321 ttttcaaata gtgttataca gtcttctcca aatagcttaa ttgctgcatc tgtagctatc
    64381 tttgaacatt ctttgtcatt tataactgct ggtgttaagt acccatactc taattcagca
    64441 tctgctctat atgcttctgc tgtagatttt gctatacgtt ctaaaattcc aggaatttgc
    64501 tttctaagct ctggattaaa tagccttatt gtaccttcta agacagcttc actcgcaatt
    64561 acgttaaatc tagttccaga atttaaaact ccaacactca caactaatgg ttccagagga
    64621 cttacttctc tactaaccat agattgtaga ttcataacta ttgctgaact tgcaagcact
    64681 gcatcaacac cttgatgagg aagtgaacca tgaccacctc taccttttac agtaatttta
    64741 aagaaatcag cagaagccat tcttggtcct tcttctaccg atatggtccc agattctaca
    64801 tcagtccaaa gatgtattcc aaacacacta tctacacctt ccatagcacc atcttgaatc
    64861 atagctcttg cacctttacc aacttcttct cctggctgaa aaaataattt tacagttcca
    64921 ttgatactat ccttaatatc atttaacact tttgctgccc ctagaagcat tgatgtgtga
    64981 ccatcatgac cacaagcatg cataagtcct tcatttttag atttgtattc tacatcagtg
    65041 cattcaacaa cttgtagagc atccatatca cccctaagtg ctacagtctt tcctggatta
    65101 gctcctttta tagttgcaat tacacctgta cctccagctg atacatatgg tatccctatt
    65161 ttatcaagtt cttctttaac tctctttgat gttctcactt cttccatact tttctcagga
    65221 ttttcatgaa attcccttct aagcttaatt acatagtctt tataactctt tgttatttct
    65281 ttaatatcca ttccatacct ccaagtagta cacattcttc ttatttaaaa tactttttat
    65341 cacttaaata ctatattaga tttacaaaga tacctgctat tactacagaa gctattgtaa
    65401 ctgtagtaaa tcctccaaca agcatctttg gaagcatctt atccattaaa aattcttttt
    65461 cctctggtgt ttcagccaaa gcctttactg cctcttcagt taatatatag tttggtggaa
    65521 aaccataaag tgatgtaagc gaaactgaaa aagccatttc tttactttca cctaaaagct
    65581 tacctactat aatagagaat attcccatac ctattacacc aaatattatg attcctacaa
    65641 gaggaactgc catttcaaca agcattgctg gtgtagcttt tgctaaccct gcaaatataa
    65701 aagccatcaa tgatgtcatt aaccatccaa atgaaccaga tttattaagt ggttttctat
    65761 caactattcc aagttctgat gctattacac caaatattaa acatataaca tatcttgata
    65821 caacttcatt tgtaagattt gtaaattgta ctgctaacca tgctacaaat cctaatctaa
    65881 gtattatcat atatgtcgta tcatattttt ctggtaagtc tggtattatc ttaaatctgc
    65941 ttttttgttc aggtaaatcc ttaacttttt cttcatctgt atttacagtt acttttccac
    66001 ttctaaagtc tgataaaagt ctttttcctt cttttttaag cattaatgct gtaataggat
    66061 aacccgcaaa tccttgtgca acatacatca aaattgcaag tactgataaa cttgcaagac
    66121 cttttgctgt agcagcatct gccatcatta tagatgcaac tagccctcca gtaagaggag
    66181 gtgtagctat tactgctgta tcccatccaa atactactgt ccctaatgcc aaagcaccta
    66241 cacatattcc tactattcct gccaaggcta ttactattgt tttccattga cctgctaatt
    66301 ccttaatact catcatagtt cccatatgag ttattaacaa aagcatacct aattgagcta
    66361 atggtgttcc taaagcggct aagtccacaa tattttctgg gaaaaaagtc caaaatccta
    66421 ctataaatat aattgctgat acaaaaaccg atggaacaaa agctttagtt tttgctgaaa
    66481 ctatatctcc tatcgtcagt gatactaaaa ctagacaaaa agctgttatt gcctccatac
    66541 aaaatccccc ctcataataa atatattttt ataaaatgta tgtatagtta tccattattt
    66601 tactactttt gaaaaacatt tcaagtcaaa attcgatttt tttcataaaa ttcgataaat
    66661 tccataaatt aaagttagtt ttctaaatta ttctttttgt aaaaacgtta tccccaccat
    66721 tggctattta actctattct tacaaagaga attaaatgta atttgcaaaa aataaaacat
    66781 aggatacatt ttattcataa aacatctcat aaatataaaa tgaattgtct ttatgaatct
    66841 taatatatcc tatgtttgta agtttaatgt gtatgttagc tatggtgtaa aatttgtata
    66901 ctagttattg tgtaacctac tatatactcc atttttgttt actagctctt catgagtacc
    66961 tctttcttca attcctttat ccgtcaatac tatgatttca tcagcatttt ttatagtagt
    67021 caatctatgt gcaacaacta aatttgttct atctttactt aattcctcta aagactcttg
    67081 aatttctctt tctgttacat tgtctaaagc agatgtagcc tcatccaata ttattattgg
    67141 aggattcttt aaaaagattc ttgaaattga aattctttgt ttttgcccac ctgataattt
    67201 tacgcctctt tctcctatat aagtatcata tccatctggc aaagtctcta caaagtcatg
    67261 tattctagct tttttagcag cagctatcat ttcttcatct gtagcattag gattcccaca
    67321 aagaatatta tctcttatag ttcctgtaaa taaaaataca tcttgttgaa ctatacctat
    67381 attttttctc aatgatttta aactaacatc ttttatactc tttccatcaa tttttatatc
    67441 acccttatca aattcataaa atcttggcaa tagattacat aatgtagtct ttcctcctcc
    67501 agaaggtcca actaatgcta tagtcttacc agcttttata gataaactta aattatccaa
    67561 aacttgagtc ttatcttcat atgtgaaaga tatattttct atctcaatgt caccttttac
    67621 attttcaagt tcaataggat ttttagcttc tttttgatgg tcttgttcca ttatctctat
    67681 gaatctttta aaacctgtca taccattttg atattgctct gtaaagttta ttaatttttt
    67741 cataggttgt ataaacattt ttacatatag tatataagca gcaaaatcac ccaaagtaat
    67801 ctttcctata taagtaaaat aaccaccagc tattacaact acccactcta agatatccat
    67861 gtataaattc ataccagagt aatattctgc cattacctta taagaatctt gtcttgctct
    67921 tctaaataat ttattgcttc ttacaaactt atttaactct tctttctcag tacaaaaaga
    67981 cttagttacc ttcatacctg ctatactatt ttctaaagta gcatttacat cacctatagt
    68041 aactctactc ttcataaaag caatattcat cttatctttt ttagctattg caaaccaaat
    68101 tataaacggt aatatagcaa atattataag cgtaagagga atatttatat ctataagtat
    68161 aaagaatgaa ccaaccaaca ttactataga aatgaataaa tcttcaggcc catgatgtgc
    68221 aagttctgtt atatccatta aatcatttac tattctagac atagttactc cagatttgtt
    68281 attatcaaaa tacgtatttg gaagtctttg taagtgtgta aatacctcat ttctcatatc
    68341 agcttgcata tctacaccaa taacatgtcc ccaatactgc ataaaatagt taagccctgc
    68401 ttttgctata aatataagta taagtgctac tgcaaaaact actaacattc ttaaattttt
    68461 atttggaaca acgtcatcca ttatatttct agttatcata ggataaacta aatcacataa
    68521 ggaaaataga aaagctgcta taaggtctag tgtaaaaatt ttcttatatg gcttataata
    68581 tttgacaaat tgttttatca taagtattaa atccctcctt tattagtact tctaaaaaat
    68641 acccataaat tagtataaca taacaataac tttaaatctt ttataaactt acaaagtaat
    68701 aacaatcttt ttcataaaat tgaagattta tatcatatag ttgtatactt gaaacaacat
    68761 aaaaagagct atatctctat attttaaatt ttataaagat acaactctat atttaatact
    68821 aaattttttt tataaataca aaactacttc aatgcattta atatcttttt atctaatgct
    68881 gttgtattta tacctgttat atatcctgtt gcctttattg taggtatatc ataagttgtt
    68941 ggtagtatag tagtagatac gattaaatca gcaccttctt gttttgttga acattcagca
    69001 attttacatt gctcaacttc tgcttgtata ttattttctt taaccaatct ttctactctg
    69061 tcacaaacta ttgttgatgt tgcgattcct gctccacagg ctactaatat ttttttcata
    69121 tattgtcctc ctacaatttc tttaatattt tataactcaa aataaaattg ataaatttct
    69181 tatatcttta tttatataaa taattatatc attttatata agaagaacat cttaaaatta
    69241 ttcttttaat atgtttttta tttcaacatt gcttatactt aaaatttcat tttttataca
    69301 agactctatg tactttgata tatttttata atcatttaaa ttaaactgtt caatattcaa
    69361 tttatattct atatcactga caatacctat caaatcagac ttattagata aaatatcctc
    69421 atacttacct tttctagtta cttccaatct tttaaatcta taatttttat atccttctat
    69481 gataatcaag tccatatctt catataattg aatcatttta tataatggat tcttctcttt
    69541 tagttcttca atatatgcta ctcgtttatc tgatattata cagacttttc tcgccccaga
    69601 ttttctatgt ttataagtat cttttccttc ctcatccata tcaaaatcat gacaggtatg
    69661 tttaataact ccaacacgat accctttttt atttaattct tttattatgc cttcaatcaa
    69721 cgtagtttta cctactcctg aatatgagac aactgacaat atattataca taaaattgtg
    69781 tcctttcata aaactatcta ataacaacat ccactaattg attttctttt attgtctcat
    69841 tctttttaat cttaatcata caattacttc ttagagttgc agataatcta gcctttgcat
    69901 ctttcttatc atttagctct acatacaatt taccttcact tgtatatagt tttccactta
    69961 caaatctatc tttatttgaa agtttattaa attctccttt aaatatagct tttatatgat
    70021 gtgttccctt cttatatgtt aaatactcaa taacaggaac tatcacatta tcaaatacca
    70081 ctattgctgc atgtggatta ccagaaagac caaataatag cttttctccc aatgtaccta
    70141 cataacaagc tccaccaggt ttaatgttta tattccaaaa taattctgtt gcccctattt
    70201 ttttgaatac atctggaatt aaatctttat ctccaacaga aacaccacct gtggtaatta
    70261 aaaaatctac actctgtaac atattcttta cctttttttc taactccaat atatcatcag
    70321 aacaattgca tattgtatct gcttgtattc caagttttaa taatcttgaa tataaggtat
    70381 atctattact atcgtatatt ttaccattct ctaaagtctc atttatatct tgtagttctg
    70441 tacctgtatt caaaattcca acttttaaat catcataaac agttactttg gatattccaa
    70501 gacttgctaa tactccaata ccatcatatc ctatattctg atttttatta ataatcaatt
    70561 gccccttttt tatatcctca cccttaaata tgtaattatc gtattccttt aattttatat
    70621 ttaaagttat catatcacct ataactgtta catcttcttt ttttattaca caatttgcac
    70681 cctgtggtat ctttccacca gtcattatct tcactgcttc atttttattt aataccctat
    70741 taaatacatc tcctgcatac aaagtcccta taacctttaa atttctattt tcagaatttg
    70801 cattatatgc ataaccatca tagggtgacc tatcaaatgg aggactatca attgttgaat
    70861 atatatcttc tgcaactacc ttatttactg catctataag atttactatc ttgaccctgt
    70921 ttattggtaa aacatttttt tcaataattt ttatggcatc ttctaattct atcattttaa
    70981 atactcccca atatattttt tatttaagat atttctatgt aatatattat agattataaa
    71041 agttggaaat acttttatct tatatttaat tataactaat agttatctat aagtgcagtt
    71101 caaattttat aaatctaata aaaaaactgt tcccagctag aaatttcctt ctatcttgaa
    71161 acagcatcat atgctttaga atattttatt ctaataaagt tccttttatt atttttacaa
    71221 ttttatcact ttcaatagtt tttatagatt ttattttgtt atccacaata cttattgtaa
    71281 gtacctcttt ttttaatatt ttgttatctt ctttcaatct ataactctta actactttac
    71341 tgccttcatg attatatgct gttaaatcat aattcgcatc tcctacaatt tcatttattc
    71401 tggaatcttc aacaccaaca tactctccca ggtcaatatg tctaaaattt tctagtgata
    71461 cagccgattt ttcatggtca cttttttcaa tcactatact agattcagca tcaatgactg
    71521 atataccttg tgatgagaaa gaattggttt caacattgac aactttattt tcgttaatat
    71581 caacatataa agcacttcca tctaattcat catttccagt atattttgga taaactaatg
    71641 tcatataact tgatgtattt atatcttgca ttgtatttga ttcttttaaa actttaggtt
    71701 ttatataata aaatgtatta taaggtatac ccatattctt tataatgtac ttataatctt
    71761 tattcataat ttcattaaca tcattttgaa cttttgtcat agttttttgc tgtgttgctt
    71821 tacttgctac ttgatttttc tctttagtat tttctttatg acatccaaca agtataatac
    71881 ctaaaatagt tacacaaact aatgaccttt ttaacttcat aaatcaatcc tcctttctta
    71941 aattttatag tatttatcta tatctcaatt tacagttatc tcttttttca ataattatat
    72001 ttattatatt ataaaataat tatataatat ttatttgaat ttaataagat taagaagcta
    72061 attgtaattt ttctgtaata aaaaacactt taaagttgaa ttttgaaaat tcaatttacg
    72121 atatttttat tgtaagtacc ttacaacatt ataccaaatt attcctaaac aatcaaaaac
    72181 tccatgaata tttaaaggtt ttctatttta aaaatcacct ttgactatta atttatcaaa
    72241 tatgttataa tagttttaga taatttaagg aggattaaat aatggatttt aaacaacttg
    72301 aagtatttgt tgctgttgca aaacatcaga gtttttcaaa ggctgcaaga gaactttttt
    72361 taactcaacc tactgtaagc gcacacatac agaatttaga gagagagcta gaaactgttc
    72421 ttataaatag aagcaacaaa gttattacac tcacaaaatc tggtgaaatt ctttatgaac
    72481 atgctatata tatattgaat aattgcaaac gtgcaattta tgatataaaa gaatattcag
    72541 gaaaaataga aggtattata gatatagcat gtagttccat acctgaaact tatattttac
    72601 ctgattttat gaagagtttt tctatgagtt atccagatgt aaaattttcc ataagccatt
    72661 atgattctca atatgctata tcagaaattt taaatgaacg aataagcttt ggattagttg
    72721 gttctaaaat caataatcct caaatagagt acctagactt attagatgat gaacttgttc
    72781 ttatcactcc ttcagatctt aaaattgata ataaaaataa ttgtatcgat ataggagaat
    72841 tggcttatct aaattttatt atgagaaaag aagggtcagg tacaagaaac ttaatactaa
    72901 acacacttag taaaaataac tttccagtaa gtaaattaaa tgtaatcgct catgtagaat
    72961 caaatgaggc tattaaggaa atggttagat taggtcttgg agtatccttt atatcgtaca
    73021 tttcagctat tgattatctc aatgcaggta aaataaaatg ttataaaata aaggatgttg
    73081 attttactag aaagtttttc ttcatttact ctaaaaagaa aactttttcc ccattagaag
    73141 ataaatttct aaacagatta tgtgagtatt tcgaaattat aatataataa ctttaataaa
    73201 gtagtgctta attttgagtt tataactaat taataagcta attataacta tcacatagat
    73261 gcttataaat tattatgaac catctttctt ttttatttaa tttagtcaaa aaatccctcg
    73321 ttcaaatgaa cttgggattt ttttatttat actactccaa tagcagccaa tactatacaa
    73381 ataatcataa ctgaaattaa tatcgtagtt gtctttacct tttttcctaa taaccaatac
    73441 ataataccga atatcatagc tggaagcata catggcatta tttggtctaa gtaagtctga
    73501 ataggctctg cccattctcc actacctaca ttaacactaa gttttaacat tacattagat
    73561 gcagtcatac ctccaattac cataagccct aacattgaag ctgcttccat aacttttgaa
    73621 actatacttg aaccactcac atctttaaag aattgagttc catacttaaa tcctttatct
    73681 agacatatat agcgtataat aaaatgagga acatttatta ttaaaaggaa taaaatcggt
    73741 cccattatgt taccctgaga agctaaagct ataccaaccc cagctgctat aagctttaat
    73801 gttccccaga aaaatgaatc tcctatccca gaaactggac ccattaaact tgatttaaca
    73861 gcatttatac tattagcatc aaattcttta ttctttgcat tttcttcttc catagctcca
    73921 gatataccta ccaaaagagt acttatatga ggagtaactg acataaattc taaatgtctt
    73981 tttaaagcct tagatttctt ttctttatca tctttatata atctacggat tattggtgcc
    74041 atcatgtatg catatgctat attttgcata cgttcgtagt tccaagatga atctaatgtc
    74101 aatgaccttc taaaacattt ccaaaagtct ttcctcgtta ttttactatc tggtgaaatt
    74161 gtctctaact tcttagaact cgttgtcatc tactattacc tccttctctc ctacaaagtt
    74221 aacatatatt aaagctattg ctaatccaaa caatgcaact cctgttactg ttatgtttag
    74281 gtaagcaacc aatataaatc ctaataataa aaatgctact gttttcttat taagcatcat
    74341 tctagctaac atggcaaaac ctattgctgg aatcacgcct gctgcaacat ccattccatg
    74401 agttacatat gatggtataa atgaaagtat tttttctatt actggaacac ctaatgaaaa
    74461 tcctatacct actattattg ctaatattaa tttatttcct ataccaaata ataattgcac
    74521 acgttctacg ccttcaatat tcccctcttc tgcataacgg tcagcaatat gagctcccca
    74581 tgtaagtact actgtcatta agaagttatc tataagcaat actagagttg ctataggaac
    74641 tgcaagtaca actgctgctg atacatcttg acccgttaat attacaaacg ctgtggcaat
    74701 aatagaacca gacacaaaat caggaggatt acttgcccca acaggaaatg cacccataaa
    74761 tactaattct aatgttgaac ctattactat acctgtatga agattaccta gtgctaaacc
    74821 aacaagtggt gcaacaacta taggtctatt atgcattgta gaacctacaa aactatgcat
    74881 atatgcaaag aatgcaatta gagttatcaa aataacttgt gtaaattcca ttttcatccc
    74941 cctaaaatta tattaatttc attacatttg tagcatcatc atcaggaact aattgtacaa
    75001 atacatttac gccttctgaa tctaactctt taatcatctt tatatcatct tttgatacat
    75061 gcactgcttt agatatattt tcacgattat catctgattt tgttccacca aggtttatag
    75121 atttaatagc ttttacctct ttagcaagtc tataaacatc ttctacagat tcacaaagta
    75181 tcaataagtt gtatttatca gtaacacctg agttaagtgc ttttatagaa tctgctatgc
    75241 ttttcattac taacttaaca ttagatggtt tagccatttt aagtcctgcc attctcaatt
    75301 catcttttaa taagtcatca cttgctatca atatacagtc tgtacttaaa aactttgtcc
    75361 atgtaaatgc tacttgtcca tgtataagtc tgtggtctac tcttactaat ttaatcatta
    75421 taattcctcc ctaatttttt tgatttcatc catgaatgtt tttacgtgtt ctacactaac
    75481 atccccaaaa tctttgtaat tatctttaaa gtaacttcct attattgcca tatctcctaa
    75541 tttaagctgt ttttttgcat tttctaatgt aactccagca gctataacca atgggaagtc
    75601 tcctaaattt ttacgaaaca gttctatttt ttccattgat gtttcttgac ctgtagcatt
    75661 ttctgtaact gctatagcat cacatcttgt cattcctatt tttaaatctt cttcaacatc
    75721 attttctgat aatactggct gatatttaaa acgtacgcct ccaattaaat acgctgggca
    75781 ttttgaacgt tgtaatttaa aaaactcttc taaagtagct tcatctctag gtttaacatg
    75841 acctactaca gaatcaacct gtatataact agcattatat tttgttgcca gttcaaatcc
    75901 catagtatca acatttaaac agtttactcc atatggtatt gataaattag cttttgatac
    75961 atattcaagt attctttcta aatcataata attaccatag taattttcta acattattcc
    76021 atctacacca ttttcttcaa agattgtaat ctctttttta gctctttcaa agatatcttc
    76081 tggagtatct ccttttaagt gtatcattgc tataattggt tttttacttt taaatactga
    76141 taatattccc ttttttttca taaactaaaa tacctcttct tcttctttaa tttgtaatgt
    76201 cacgctttgt attcctcttc tagattcttc cactaattgg tctatatctt caactgttaa
    76261 ttcatcagaa aaccttgtaa gaagttctaa taccatattc aaattcattc cagaaaataa
    76321 cctaacatta tgtagattag ttaatcttaa cattgctgta catacacttg ctccatataa
    76381 gtcagataaa attatatatt cacattcttt atcttctgat attgtttttt ctaattctaa
    76441 agcaaaatct gaagcacttt gtccagggta caaaccatac gaactgacac aatctgctaa
    76501 atctcctact atcattttta ctgcatttaa aagccctttt gaaaagtctc catgagatgc
    76561 taatattatc tttttcatac tcatcctcct actaaattat agattatatt tctgctgata
    76621 ctgcatattt gtacttatca cttcttataa attgctcatt gtaatataag acatcattat
    76681 tttctgtata caccgattgt cttactttca atagtggcat attacttgca catttaagat
    76741 ggtcagaata ttctttgttt gaatgtttta cttcaaatat attttctact cgtttaggta
    76801 atgtgcttat attattagat ataacctcca ttaaagattt atcttctaat tcttctttta
    76861 ataaaaacat gtaatctatt ctaaaatagt caacttcaaa aataacaggt acttcatcta
    76921 ttaatctaag tcttttaata catattacct tctcttctag ttcaatactt aaagcttcag
    76981 ctacttgctt atctgctttt tttattaaaa cagagattat tttggtactt ggttttgcat
    77041 taatacgatg acaagaatta gtaaaactat ttcctgcaca tgttgcttct attctctctg
    77101 gtattgttac ataagtccct ttaccacgtt ttttacataa tatatcttct tttacaagtt
    77161 cattaagtgc atttctcaca gaaattctta tattttattt atgtttattt atatttattt
    77221 atgtttttat gagtacattt atttacaacc tatctaaaac aatttcttta ttctatttta
    77281 tttatatttc tttatttgta ttttatttta ttaaactgtc atggtggcaa aaaaggtggc
    77341 aaaaataatt tgccacctaa aataatcttt atttattctt tctcttttaa atttttaaaa
    77401 tgttcttcga gttcgattaa tttatcttca tccacttcat catctttact atgtaacgct
    77461 gatattaaac ttgaaattga attcttgtgt atgttcttca aaaattcctt tgtttcaaat
    77521 cttagatatt ttttctcttt taccattgca ttatagtgtg taagtttacc tattttctct
    77581 gtacttaaaa actcccttcg ctctaacctt tttaaaactg tgaatgtagt tgattcattc
    77641 cattcgtatt tttcttccat tgcggcaact aattccttag aagttaatac atcgttagct
    77701 tcccaaatat atctcataac ttttaattct gcttctggta atttactaat tttcatagtc
    77761 acaccccttt atcgaattat gtatatgtta aattctatct caataaagtt ttccaaacaa
    77821 gagaatcaca ctaaatatta ccatccaatt ttttccatct cgaaattatt cttctaaatt
    77881 tctataatat tcttctaatg cgtctagttt ttctttactt atagacttat gtgtagtagt
    77941 aagagaacgc attatttttc tgcttttgct agattttaac acttttttct taaaagcata
    78001 atattctttg ttatctatta ttattttata atgagattga aactttataa tatctctggc
    78061 caaataacct ttgtcaacta gcctttttag tagtattttt attgtacttt tatgccatcc
    78121 ataaacctgt ctcatttctt ttacaatttc ttttttagtc actagagaat cttttttcca
    78181 taaatactcc attactatta attctgctct taataatttt tctactaata tttcttcttt
    78241 caacttatgt cactccttcg attgttctag ttcaagttaa taataagagc tttttaagac
    78301 aaaaactata ggtaattttt accaaatatt ctactgtttt agtttgtttt cttagaagaa
    78361 aaataacttt catatctata aaattattca actttcaaac tatcctgttg aataataact
    78421 aattctattg tattatttta gttgtagaat aaaactaaat cggcaaaact agagaaattt
    78481 agtggcataa atatatatga actaagaatt gtaaaatgag ttataagtta tatcatccag
    78541 ttatcaaaaa catatactct ttttgttttt gtgaaagttt tttaggtggc taataatata
    78601 tatacttaga gataaaataa aatatatttc taatattcat agttttattt tttctcaaaa
    78661 tgcgatataa taaagatgta aattcgtatc aaaaacaaaa aaagaaacta caatctatta
    78721 gcctagagtg aagtttcatt aactaaatat taatgtcgtt ttttattaaa cttgattttt
    78781 acatcaagct caaagtcact cctgccagag tggcttttta cttttctgga aataatatat
    78841 gtaataaagc tagctgttaa actagctaac actcctagta aaaattcgct catttctcca
    78901 cctccttcct tttaagggat ggaatgtaga aaatgaagct ccactcttag attgtagttc
    78961 cacaagatta ttcttgcatt ttaattataa cataatttta caattatcaa atatctattc
    79021 ttcatatttt ttat
//
LOCUS       DAEORM030000013        75583 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.013, whole genome shotgun sequence.
ACCESSION   DAEORM030000013 DAEORM030000000
VERSION     DAEORM030000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 75583)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 75583)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 75583)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..75583
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.013"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            complement(396..2675)
                     /locus_tag="KRH23_001253"
     CDS             complement(396..2675)
                     /locus_tag="KRH23_001253"
                     /EC_number="2.7.7.65"
                     /EC_number="3.1.4.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0052621 - diguanylate cyclase activity
                     [Evidence IEA];
                     GO_function: GO:0071111 - cyclic-guanylate-specific
                     phosphodiesterase activity [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="HHS5224541.1"
                     /translation="MLSDAKNNRYGLSIIAVISILVITISCLIYGSRLNKTLGEETNQ
                     YLSEIANQSVNVLKKQINGDIKLLESISIFIEGEESFEVDNILSILKRQAINSSFKRM
                     GVILPNGTAYTTDGYIEDFSKRDYFLKSMQGEVVITGKLKDVIEDDKNTNSNINVYSV
                     PIYKDNEVKGVIFATHSTKLYEKILSVPTFNGKGYSYITRSNGDIVLNPSSKNANSTK
                     ENLFSYIGRSDSISKSSINNMKSNIKNFKSGSLSYSMFGKGYYLSYAPIGINDWYLFS
                     EVPKTAISEKSYAIIKLTLSACVVLIIIFTALTIYILFIHKKSKEKLEEFAFKDNVTG
                     IGNSNKFNLEGGKFLSSHEKKNLVLIYFDIDKFKLVNDRFGYEEGDRVLKEIAEIIKN
                     IFKEQSVFSRISNDNFAIIFEKKNNRESIIEICELIRKKLSMIKTSLGVELNLIPSIG
                     VYFVEEGETNISTCLDKAMIAKTTVKRKYLKVYEIYAENLKETLIEERDIEQEMHDAL
                     KNEQFKVYLQPKVDLSTTKIVGAEALVRWQHPKKGLISPGVFIPIFEKNGFITELDMF
                     VFTQVCKNFKRWENENFPTFPISINLSRVHLENPGFISELERITKEYEIEPNLIEIEL
                     TESAIFDNTKILFKIMQTLKSVGFKISMDDFGSGYSSLNMLKDMPIDVLKLDRQFFIT
                     VGNAKKSQIVVSSIVQMAKQLDIKVVSEGVETVEQAEFLRFIGCDMAQGFLFARPMPI
                     EEYEKLILDRYSLNRKETN"
     gene            complement(2946..4400)
                     /locus_tag="KRH23_001254"
     CDS             complement(2946..4400)
                     /locus_tag="KRH23_001254"
                     /EC_number="6.3.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HHS5224542.1"
                     /translation="MKLNDIIQGLDIINVKGELNIDINNVQYDSRKVTKGTLFICIKG
                     FVSDGHKYIKDAIEKGASAFLVEEDVAIKGCTFIKVKDTRKDMAKVADNFYNHPSQKF
                     NVIGVTGTNGKTSITTILNEILTLNKNKVGLIGTIKIFDGEKDIISNSTTPESIDLQY
                     HFNNMLDNGCDYCAMEVSSHSLALNRVDETDFKLGIFTNLTPDHLDFHKDLEDYRKAK
                     EKLFFKTTMANIINIDDEGGKKIYENIKGINVPCYTYGVDTKADFMARDIKSDSDGVS
                     YRLITPSYEEVIFIPVPGMFTVYNTLAVIAACYVLGIPKPIYKEGLRLSNGVSGRFET
                     VPNDKGISVIVDYAHTPDALENVLKTTQQFAEGKIISVFGCGGDRDTEKRPLMGAIGQ
                     KYSDLCIITSDNPRTEEPEAIIKDILEGIDKKKENYHVVVDREQAIAEAISMAKKDDV
                     VIITGKGHETYQIIGKVKHHFDDKEVANECLSKM"
     gene            4564..5433
                     /locus_tag="KRH23_001255"
     CDS             4564..5433
                     /locus_tag="KRH23_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HHS5224543.1"
                     /translation="MDNKIGYLNDNFKIFNIRDKKDIQFEYHNHDFNKIIIFINGNVT
                     YFVDGIPYKLKPWDILFISNNEIHKPVIDSNVFYERIAIWISPEFMKKNSDASSDLEK
                     CFKIATENKCNRLRLNIHDIESIKSFIEQINISESNTEFGNEILRNALFIQLMIFLNR
                     IFLKNENMESTEDVFYDETIKKVLNYINSNIDDKLSIDSISSEFFISKYYLMRKFKSH
                     TGTSIHNYIVQKRLILAKSLITNGHLMSEVCNKCGFNDYSSFVRAFKKNYGVSPKNYI
                     NNKNPLDITLLDE"
     gene            complement(5646..7718)
                     /gene="ptsG"
                     /locus_tag="KRH23_001256"
     CDS             complement(5646..7718)
                     /gene="ptsG"
                     /locus_tag="KRH23_001256"
                     /EC_number="2.7.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0055056 - D-glucose transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:1904659 - D-glucose transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-specific PTS transporter subunit IIBC"
                     /protein_id="HHS5224544.1"
                     /translation="MKKVFGVLQKVGKSLMLPVALLPAAGILLGVSNALAGDALLAHF
                     PALANPTFQLIISIMESSGQIIFNNLPLIFAVGVAVGLTEGEGVAALAAIVGFLILNT
                     SMGVMAGVTEDMVDNSMYANIVGIPTIQTGVFGGIIIGIVAAYLYKKFYKIELPQYLG
                     FFAGKRFVPIVTSLVAIAIGIILSFIWPPIQEGLLSFSKNVIEANQTLAAFMEGSLER
                     LLIPFGLHHVFHNPFWYQFGEYVNKAGELVMGDQKIFFAQLKDGVNFTAGTFMTGAFP
                     FMMFGLPAAALAMVHEAKPEKKKFVAGIMASAALTSFLTGITEPIEFAFLFVAPVLFA
                     IHCLFSGLSYAIMQLLGVKIGFTFSGGLIDFLLFGVLPNRTPWYLAILVGIGFAVLYY
                     SVFRFMIRKFNLKTPGREDESETNAEVIEMSKNELASEILIALGNKDNLKSLDACITR
                     LRLVVNDINKVDKEKLKSLGAAGVMVIGNNVQAIFGPKSDSIKSDIKDIIEGKTKVES
                     TVTKNVDKNKVKKNMEVANMENALVENIDSLTNGEILDIEEVPDSVFSSKLMGDGFAI
                     KSSDGLIYSPVDGTIGVIFPTKHAIIIKSKKSGVEILIHLGIETVNLEGNGFEVFVNV
                     GDEVKAGEKLVKMDLEYIEKNGLSTISPVVFTNLEQNQKLSIKKGVTTAKEEKRVSIL
                     RDDIEKIG"
     gene            complement(8021..8863)
                     /gene="licT"
                     /locus_tag="KRH23_001257"
     CDS             complement(8021..8863)
                     /gene="licT"
                     /locus_tag="KRH23_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator LicT"
                     /protein_id="HHS5224545.1"
                     /translation="MIIQQIYNNNVVLVLDENIKKELILTGCGIGFQKKKGQEIDKSK
                     IERTFVIQDESFLDKISKLASQVDEKFFEVSTEIIAYAEENLNTKLYEYIYVALTDHI
                     AFAIKRYHENITIKNDLLHEIKRIHKKEYEIGKWAVDYINKEFDVKFPVDEAGFIAMH
                     IVNSNYKGSSKESLLITKIVKDILNIIRYYYRVEFKEDDINYDRLLTHLKFFAKRLVK
                     KEKINDTNNEIIDIIKVKYEKDYDCAYKIKTHVEKNYDYYVSQDELLYLTLHIKRVIS
                     VLNL"
     gene            complement(9124..11166)
                     /locus_tag="KRH23_001258"
     CDS             complement(9124..11166)
                     /locus_tag="KRH23_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HHS5224546.1"
                     /translation="MSILVTLLGLLVCTTISTVFSKKWSNIPLAIYQIVLGIILSILP
                     FKFSFSFNPEIFVICIIAPLLFSEGQNVSRKELLELRKPILLLAFGLVLITVFAGGIF
                     IHFLIPGMPLSVSFALAAVISPTDLVAVKSITQGLNFPKNMMSILEGESLLNDAAGVV
                     AFKVAVLATVTGVFSIEEAGIQFMITAFGGIIVGSILGYIIIKIRLSLHKWNLEEIPM
                     VIVIQIMTPLFVYFVAEEIGVSGILAVVMAGIAHGIEKEHLQNTTTKLRIISDNTWYV
                     LEYVLNGFVFTLLGFLLPSIYTGLSSKNENMALELTFISTLIVLILFVIRFIWVYLWH
                     NSFIKPKKNPLNNFFVGFLGFKDEEVVKESISKCKYSLIVATCGVHGTFTLATALSIP
                     FYLADKDVFPMRDTVLFISSEVILISLVLATVLLPRLLKNNVQESEPLLSDKEAYKLI
                     LKEAILKLSNEKAQEVQPVIHDLNEQLVDSEKGILNTPDNKLISMMIAEADQQGLLAV
                     LKLLEDGKISDRAFKLYRFYITKSRKSVQKSIFKIVKLKISMWIINRKVKKEVKEKIT
                     KIVSENKEIIKEFHHAYALSTKTAISFINKNTDEDNRHEALIAIRFYNRYLNWITRKI
                     QNDDKFEARVEYYRVMAIQSQRDSVQQLVETKQISREVAKELLENILYDEMMMIES"
     gene            complement(11318..12289)
                     /locus_tag="KRH23_001259"
     CDS             complement(11318..12289)
                     /locus_tag="KRH23_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHS5224547.1"
                     /translation="MKKEESLLKVEGLKKYFEVKSGLFDKEIKCVKAVDGISFDLKKG
                     ETLAIVGESGCGKSTAGRTILRLIEKTEGKVEFNGVDIYKLEKEELRKLRPKMQMIFQ
                     DPYSSLNPRLNVEQIISEAVIEHNLVPKNEIKDNILNVVESCGLSKYHLNRKPGEFSG
                     GQRQRIGIARALALNPEFIVCDEPVSALDVSIQSQIINLLMDLQDKYKLSYLFISHDL
                     SVVNHIAHRVCVMYLGSIIEIATKGELYLHSQHPYTKALMSAVPIQDPTIKKNRIILK
                     GDIPSPTNPPSGCKFHTRCPYCKEICKKEIPVLKEISRNHFVACHLV"
     gene            complement(12290..13267)
                     /locus_tag="KRH23_001260"
     CDS             complement(12290..13267)
                     /locus_tag="KRH23_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHS5224548.1"
                     /translation="MSKALIEVKDLKVYFHTDKGIVKSVNEVSFNINEGETIGIVGES
                     GCGKSVTAMSLMKLLPTSKIEGGEIIFRGKDILKMNEDELMGIRGNEISMIFQEPMTS
                     LNPAFTVGSQIIEGIMIHQDLSKEEAKKKVIDMIKLVEIPRAEEIYNSYPHELSGGMR
                     QRIMIAMALSCNPKLLIADEPTTALDVTIQAQILDIMKNIKEKLNTSIMMITHDLGVV
                     AEMCDKVLVMYAGKIIEVAEVVELFKNPKHPYTIGLLKSKPALGKNKDKRLYSIPGQV
                     PNPIGMPDSCYFSDRCEKVCDKCRTQIPPLIELNSGHSIACWLYKKEEI"
     gene            13486..15045
                     /locus_tag="KRH23_001261"
     CDS             13486..15045
                     /locus_tag="KRH23_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HHS5224549.1"
                     /translation="MKFKKLASLILVSSLMLTFTACASNDKDKSSGSKSGGTVVIPMA
                     SDPDIINGAFANVKEDSLASNIVYAPLYTYEKGNLVNYLAEKVDFKDSKELTIKLKSN
                     LKWHDGKPITAEDVLFTFNTVLDEKQNSPSRQYLLVGEKPVKVEKIDDLTVKITLPTA
                     SESFLYGISKISPIPKHVFEGESNIAKSEKNNNPVGSGAFKFKEWKKGESIVFEKNAD
                     YFGGEPKADSIALKIIPNEASQEAALNNGEISLMKTSAEGYEKAKSNSNLQTYTYSEE
                     RLNYIVFNQNISNMANKEVRQALSYALNRNEMIESAYGKEGSVPAKSILVPEADFYTE
                     EGVEGYDQDTNKAKDLLDKSGVKIDKLKIGYNTGRFGHKNYALVAQQELKKIGIEAEI
                     VPYESKAFFNILFSNSTECDMYVNGYAWGLEPNPYRGMFETGQYCNQTKYSNAEIDAL
                     WEKGFTELNKEKREEIYKQIQQDISKDAPIYTIDYEQNLMAAQKNLKGIKDAKPSPAI
                     LFEDWSKLYVE"
     gene            15151..16110
                     /locus_tag="KRH23_001262"
     CDS             15151..16110
                     /locus_tag="KRH23_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHS5224550.1"
                     /translation="MLKLILNRVKVLIPMLILISILSFGLLELAPGDPADAYINPLMS
                     SQDIENIRVNMGLDKPVYIRYLNWLKNTLSGNLGISYINHMPVTEQIMEKMGNTFILM
                     GTSLIFSILVAIPLGIFLAVNKNSITSKVSSVFNYIGVSIPSFWIGMILISIFSVKLN
                     IFPSGGMHTIGNDSIGDLVKHLVLPVITLGLYNTAIFTNYVEASVNEQLKKQYVITAR
                     AKGLSEKVILFKHVLKNSLTSLVTILGMSIQKLVTGAFVTEVVFSWPGMGRLMIDSIF
                     SRDYTVIMAITMLSALFLILGNLVADILYLLIDPKIKSSKGGF"
     gene            16113..16925
                     /locus_tag="KRH23_001263"
     CDS             16113..16925
                     /locus_tag="KRH23_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHS5224551.1"
                     /translation="MFTSILKKLKKDKSFAFACITLSIIIILIITSFILNIDSNAIDT
                     TSKLQEPSLKHIFGTDELGRDYFSRALYGGRISLSVGILSMLISVVFGTAVGVISGYI
                     GGKLDQFLMRLVDMLMSIPSFLVLIVLNTYLTPKVSSIILIIGFLSWMEVSRIVRGET
                     LKIKENEYCLAAKATGIKTRNILLRHIVLNLKETIVVAGSLNIANAILTESALSFLGL
                     GIQLPLASWGNMLQDAQRHIFDKLYLAVFPGLLIFLTVMSLTIISKKFSSNT"
     gene            complement(17141..18043)
                     /locus_tag="KRH23_001264"
     CDS             complement(17141..18043)
                     /locus_tag="KRH23_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HHS5224552.1"
                     /translation="MDIKQLKYFVEIVKSGFNLSIASKTLHISQPALSQIIKNFEESE
                     DVYLFERYKGRLNGLTPAGERFYVNAEHIINEYKNMMEDLREDSVQFKGKVRIGIPPL
                     ILGIAFSDVVAQLVANNPDIEFDIVEKGAYDLNRMLILQELDYAVLLHPHKIDKSVVT
                     EHVLQEDELTAFLNINHPLAKKDKIDWNDLNEQLLAIFNPTFMIHHKLMQKFTDENVK
                     LKRYIMSGSWDFLLLSTTNSDFITILPSPVHDFFENSKIIEKPFNHPITWKVILCRPK
                     KERYSHVDQHVFKFIIDFFSKKNS"
     gene            18398..19576
                     /locus_tag="KRH23_001265"
     CDS             18398..19576
                     /locus_tag="KRH23_001265"
                     /EC_number="2.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003985 - acetyl-CoA C-acetyltransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="HHS5224553.1"
                     /translation="MKDVVIVSAVRTPIGSFGGVFKNTSAVQLGTIAVKEAISRVGLN
                     LSEIDEVIIGNVLQTGLGQNVARQIAINAGIPNSVPSYTVNKLCGSGLKSVQLAAQSI
                     TSGENDVVIAGGTENMSQAPYIVPTARFGSKMGDITMVDSMLTDGLIDAFNQYHMGIT
                     AENIATKFEFTREMQDKLALESQNKAENAIKNNRFKEEIVPVDVLIRRGKIETIDKDE
                     YPKLGMTFEGLAKLKPAFKKDGTVTAGNASGINDGAAMLILMSQQKADELGIRPLAKI
                     KSYASAGVEPEVMGTGPIPATRKALKKAGLSINDIDLIEANEAFAAQALAVKNELQID
                     SSKLNVNGGAIALGHPIGASGARILVTLIYEMQKRKVETGLATLCIGGGQGISMVVSR
                     "
     gene            19585..20241
                     /locus_tag="KRH23_001266"
     CDS             19585..20241
                     /locus_tag="KRH23_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008410 - CoA-transferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CoA transferase subunit A"
                     /protein_id="HHS5224554.1"
                     /translation="MNKIVSIDEALSHVKDGDTIMVGGFMANGSPENLIDYLCSKNIK
                     DLTLICNDTGFIDKGVGKMVVNKQFKKIIASHIGLNKETGRQMNNNETDVELVPQGTL
                     AEQIRAAGYGLGGILTPTGIGTLVEEGKQKIVVDSKEYLLEKPIYADVALLFASKVDK
                     AGNLVYKGSMNNFNNLMASAAKITIVEADEIVEIGDIDPNEVNTPGIFVNYIVEGGNL
                     "
     gene            20241..20906
                     /locus_tag="KRH23_001267"
     CDS             20241..20906
                     /locus_tag="KRH23_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008410 - CoA-transferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacid CoA-transferase subunit B"
                     /protein_id="HHS5224555.1"
                     /translation="MDKLEMQEYIANRVSKELKDGAVVNLGIGLPTKVANYIPDNVNV
                     ILQSENGFLGLGSAEDGNSSDETIVNAGGQPVTILPGGCFFDSATSFGIIRGGHVDIT
                     VLGALQVDKYGNIANYMIPGKMVPGMGGAMDLVTGAKKVIVAMEHTSKGSAKILNNCT
                     LPLTATNAVDLIVTEMGVMEVTSDGILLKEINPAFTLDDVISATEAPLILSDSLNGKI
                     SVV"
     gene            21011..21787
                     /locus_tag="KRH23_001268"
     CDS             21011..21787
                     /locus_tag="KRH23_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxybutyrate dehydrogenase"
                     /protein_id="HHS5224556.1"
                     /translation="MVKDKVVFVTGAASGIGKQIAESFLKNGAKVMFSDINQEALNNT
                     ITELQKKGYDCMSVKCDVTKEEEINHAIDKTVEKYGRLDILINNAGLQHVSMIEDFPT
                     DKFEFMIKIMLTAPFIATKKAFPIMKKQGFGRIINMASINGVIGFAGKAAYNSAKHGL
                     IGLTKVAALEAADSGITVNALCPGYVDTPLVRGQFNDLSKTRNIPLENVLEEVLYPLV
                     PQKRLLDVQEIADYAMFLASDNAKGITGQACLLDGGYTAQ"
     gene            21864..23198
                     /locus_tag="KRH23_001269"
     CDS             21864..23198
                     /locus_tag="KRH23_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HHS5224557.1"
                     /translation="MSIIAPIGIIIGIIAIIYFSVKEIHITIAAPIATLIVVILNKMD
                     VVTSMLGADKNNYMGALGNYIMSYFAIFLLGSILAKFMEESGATVSIADFILNKFGSN
                     HPYRVLVAIFIVSFILTYGGISLFVVMFAVIPLARTLFKKLDISWNLIQIPLWLGIAT
                     ITMTIIPGTPAIQNVIPIQYLNTSLTAATIPSIVGSIGCATFGLVYMKYALNKSIRKG
                     ETYATYTSELEEESLDRELPGFFASIFPLLALVIIAITGSTFGSEFMKKNVIYIALIV
                     AILLSAFLFHKFLSSKIQTLSIGASGSIGPIFATSSAVAFGAVIMAAPGFDVFSKLIM
                     SIPGSPLISLTVLTSTMSAITGSSSGALGIVMPNFADYYLSTGLNPELIHRVSTIASN
                     ILTIVPQSGVFLTFLSLSKLTHKTGFKETFIVVAVGSLIAEIIVITLGLLMY"
     gene            23695..24570
                     /locus_tag="KRH23_001270"
     CDS             23695..24570
                     /locus_tag="KRH23_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CAP domain-containing protein"
                     /protein_id="HHS5224558.1"
                     /translation="MMRRNIPTKLKTILALGVLTLATASSAVTASASSLENNVNISNK
                     SLVYSNTKYKFSAKPNCSVKPELKPDKDNSCKDKNHNDKNCNNTNKPEDNNNSDSTNK
                     PDNNKPESNKPEDNNNSGSTNKPDNNKPESNKPEDNNNSGSTDKPDNNKPDDNNNSGS
                     TSESFSAYQKEVVDLVNIERAKAGLNPLTLDSSISNVATKKSQDMIDDNYFSHNSPTY
                     GSPFDMLKKFGISYKTAGENIAMGQKTPKEVVNAWMNSEGHRKNIMNPNFSKIGVGVA
                     QKSGGSIYWTQIFVG"
     gene            complement(24963..28502)
                     /gene="nifJ"
                     /locus_tag="KRH23_001271"
     CDS             complement(24963..28502)
                     /gene="nifJ"
                     /locus_tag="KRH23_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0016903 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors [Evidence IEA];
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA];
                     GO_process: GO:0022900 - electron transport chain
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HHS5224559.1"
                     /translation="MAKFMKTLDGNTAAAHVAYAFTDVAAIYPITPSSTMAEVVDEWA
                     SQGRKNIFGQTVNVVEMQSEAGASGTFHGSLQGGALTSTFTASQGLLLMIPNMYKVAG
                     ELLPGVFHVSARALASQALSIFGDHQDVMAARQTGCVLLASGSVQEVADIAPVAHLAA
                     IEGRLPFIHFFDGFRTSHEIQKVELLENEDYASLLNFEAVQAFRDNALSPNHPVARGT
                     AQNPDIYFQTREASNKYYQNIVGIVEKYMEKMSNLTGRKHSLFDYYGAEDAKYVLIAM
                     GSVTETIEETIDYLNAKGEKYGLVKVHLYRPFSMKHFLDAMPSTVERICVLDRTKEPG
                     STGEPLYLDVRDVFYGKENAPMIIGGRYGLGSKDTTPSDIKTVFDNLVSEQPKNGFTV
                     GIVDDVTNTSLTPSEPIKIASKGTIRCKFWGLGSDGTVGANKQAIKIIGDHTEKYAQA
                     YFDYDSKKSGGITMSHLRFGDTPIRATYLIDEADYIACHKQSYVYQYDLLKGLKKGGT
                     FVLNTIWDQAGLEEHLPAHMKQYIAKNDIKFYTVNAVKLGQEIGLGNRINMIMQSAFF
                     KLAEIIPEEDAVKYLKDSIVKAYGKKGEKIVNMNYAAVDAGINALVKVEVPASWENAV
                     DADKGEVKEPEFIKNILRPMTAQEGNNLPVSTFNGIEDGTFPCGTAAYEKRGIAVDVP
                     EWIIDNCIQCNQCSFICPHACIRPVLVTEEELANAPEGFEAKKALGKGLEGLKYRIQV
                     SPLDCTGCGNCADICPAKEKALVMKPIDTQLDTELDNWAFAVNPDEVAPKVDVMPANT
                     VKGSQFRQPLMEFSGACAGCGETAYIKVVTQLYGDRMMIANATGCSSIWGASAPSIPY
                     TCNHEGKGPSWANSLFEDNAEYGFGMYTAVKQIRNKIVDAMTELVSMDICEDAKAVFT
                     EWLDSRNDGEASKVASAKVVELLEKPACDCTDEKAKELVKAIKDRKDYLVKRSQWILG
                     GDGWAYDIGYGGLDHVLASGEDVNVLVFDTEVYSNTGGQASKATPAAAMAKFAASGKK
                     SRKKDLGMMAMTYGNVYVAQVAMGADKNQFIKAVLEAEKHDGPSLIIAYAPCINHGLK
                     EGMGRTVANEAQAVACGYWHLYRFNPEVKAEGKNPFTLDSKEPTASFKDFILAQVRYS
                     AIAKQFPEEADGLFAKAEADAKERYEGYKKLAE"
     gene            complement(29020..29589)
                     /gene="pduL"
                     /locus_tag="KRH23_001272"
     CDS             complement(29020..29589)
                     /gene="pduL"
                     /locus_tag="KRH23_001272"
                     /EC_number="2.3.1.222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate propanoyltransferase"
                     /protein_id="HHS5224560.1"
                     /translation="MKLPIALSNKHVHLSQADIDVLFGAGHELTKFKPLSQPGQYACE
                     EKVDLVGPKGTLKGVRVLGPARAHTQVEISLADGFPLGVKAPIKESGDIAGTPGVKLV
                     GPAGEVEMKEGVIVASRHIHMSNEDAAKFGVTDKQIVKVKTSGPRALVFENVLVRASD
                     SFNLEMHVDMEEGNAAGVKNGDLVELIVD"
     gene            complement(29661..30269)
                     /locus_tag="KRH23_001273"
     CDS             complement(29661..30269)
                     /locus_tag="KRH23_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HHS5224561.1"
                     /translation="MDSNDKKGLKSPEIIIINGSPRINKNCSFIANEVKAMLEECGLS
                     CKIFNIYNMDIEYCTACGFCEKTGYCKFNDDMKPLYKMFDDSKGTIVISPVHFDSISA
                     KLKTVVDRTQAIYASKYVLNKPSIDRSKKRIGMYIAVGGSKSYDSQFKGGQIVMDFFF
                     KSINTKLLHNIYLNNTDDVSYIDNQEFKDIIYKNLKIYIDSI"
     gene            complement(30277..32040)
                     /locus_tag="KRH23_001274"
     CDS             complement(30277..32040)
                     /locus_tag="KRH23_001274"
                     /EC_number="3.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004722 - protein serine/threonine
                     phosphatase activity [Evidence IEA];
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing SpoIIE family protein
                     phosphatase"
                     /protein_id="HHS5224562.1"
                     /translation="MTNGSYKMKNLVEISAMVTESTDFFNIKDDIIEKMLEVVHPTKA
                     CVNLFYKNDSKYAYLVCSQTLEYVPQIFPINSLKGAKIDFDTYPEYIHEAVNEKKIIY
                     VENVFEDSRAEGERDLAKAEGYIGRIVFPFIINNVVVGFMTCFLKEDDYITEQDIDFI
                     SSVASLLSLSIEITNKNNNVQILIDKLRGSISAINEATKKLYLNKSIDGFLENLSKQA
                     CNITNSKEALIIINSHHNKDAIVSCYNVEQKKKTNLYPMIDMFLKKESLGGYLNNLKP
                     CSKKGINLESYIYYKLQDKNETIGCIVCANSKNYTSDDLNILSILSKQVSVGMQLYEH
                     NEKEVKHKVLENELNILNKQQQLIMDKGKMDCNDEKELYFYHKPARVVGGDFYYATKV
                     DDEHIVYIVADVMGHGMVSNYVVAMIKGAFKVLCNQYNTPREIMTNLNRMLYDEFDKM
                     GVFTTCLIGIIDTKENMITVSNAGHYSPVVVKKDGTIENNLNCKKGIPIGIMEDATYE
                     NNTLSMEDYAMVCMYTDGILEIKNSSKEEYGINRLENFLKENFRLNQQLIVENLKLDL
                     KNFSSKDNYDDDILIVMLKDR"
     gene            complement(32083..32544)
                     /locus_tag="KRH23_001275"
     CDS             complement(32083..32544)
                     /locus_tag="KRH23_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224563.1"
                     /translation="MLNGIIKLFYSEIVKTKINNLDSSGYSLRDECKEIRNITLKIDS
                     VFFKLLKLAFGSILLMVAFNLNMVLGIGVFLIGVVYILYKRNMEEQVKEHINNVKNNI
                     DISKITFMDEKGRTGLNALITLLLIGLLTGFNWILVASFVVVFVFTIKNVC"
     gene            32733..33194
                     /locus_tag="KRH23_001276"
     CDS             32733..33194
                     /locus_tag="KRH23_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224564.1"
                     /translation="MQIEQLDLETRNKIYCYTKKILRKYQKGITSGKLTADKFADNIL
                     SQDFISSILNEKIVNETNFKISYRNYIETLINIQNENLSNLRKKSTKTAKCFNISQIT
                     QLKNLLSNTGYNLLIPYKYLTARDIEGIVTLINTGSIELGNERIYNYISKA"
     gene            complement(33287..33457)
                     /locus_tag="KRH23_001277"
     CDS             complement(33287..33457)
                     /locus_tag="KRH23_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224565.1"
                     /translation="MSSVNFEDLKNKFINSDLDEKIRIYTTTEGLSVEQFKELLKYYP
                     IQHLSKLEKALG"
     gene            complement(33646..33867)
                     /locus_tag="KRH23_001278"
     CDS             complement(33646..33867)
                     /locus_tag="KRH23_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003690 - double-stranded DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="small, acid-soluble spore protein, alpha/beta
                     type"
                     /protein_id="HHS5224566.1"
                     /translation="MASNNNNNRTVVPGAKEALNQMKLEIANELGMSNYQQVDKGNLT
                     ARENGYVGGYMTKKLVEMAEQQMAGKSNR"
     gene            complement(33951..35177)
                     /locus_tag="KRH23_001279"
                     /pseudo
     CDS             complement(33951..35177)
                     /locus_tag="KRH23_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427089.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
     gene            complement(35239..36171)
                     /locus_tag="KRH23_001280"
     CDS             complement(35239..36171)
                     /locus_tag="KRH23_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HHS5224567.1"
                     /translation="MDIQLNILLFFQNLRNPILNFIFLVFTISTEAPLLILITTIIYW
                     CINKKCGQKILFAIIGNFVVNLGIKEFVKAPRPIGIKGLESLRVSTAGGYSFPSAHTQ
                     TATTFWISIMTIFKKRYLHLIGAVMVLGVGLSRLYLAVHWPIDVIAGWILGIFFTVVF
                     VKIFDYIDDNKNYILLVVLLIPFIIVAIFLNSPEYFEKIGIIVGFVFGYMVEDRFVKF
                     NTDNNNKKINFSNKNKGSKNVIFSRICRFLVGIVTIGMLYIGIKLFISMLIVTLNISD
                     STMSIIFMNFIKNTVVVFYGIAGAPALFKLLKLN"
     gene            complement(36260..36787)
                     /gene="hpt"
                     /locus_tag="KRH23_001281"
     CDS             complement(36260..36787)
                     /gene="hpt"
                     /locus_tag="KRH23_001281"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006166 - purine ribonucleoside salvage
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HHS5224568.1"
                     /translation="MYKVTGKMLTEEQIKEKVYELGKKIEEDFKGEDLLVVGILKGAS
                     VFVSDLIRCIDLDVNIDFMSVTSYGNSTESSGTVKILKDLDVDIEGKNVLIVEDIIDS
                     GLTLSNLVAALKTRNPKSLKLCTLLDKPQRRKANIPVDYVGFVIEDKFIVGYGIDYAE
                     KYRNLPYIGIVEDVE"
     gene            37016..38092
                     /locus_tag="KRH23_001282"
     CDS             37016..38092
                     /locus_tag="KRH23_001282"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003415975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008483 - transaminase activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HHS5224569.1"
                     /translation="MSTNHGANLYSLSSKYGFSKEEFMDFSSNINPFGTSSLAKQYIV
                     NNIDMVSMYPDPDYIDLKTSISNYCKCSIDNIVLGSGATELISSFIHTINPKQALLLS
                     PAYSEYEKELSKINCSIEKYFAKEEDNFHINLENLIKTINAKDYDLVVICNPSNPTGF
                     AFTKVEVREILKNTDSFLMIDETYVEFTDTDTYSCTQLVDDYSNLFVIRGTSKFFSTP
                     GIRLGYGLISNTNVKNEINKNLDLWNINIIASKMGEIMFSDLDFISNTISLMNTERDY
                     LLKELKNIKSLDIYNTKGNFILCKIKTKELTAKSLREQLLPQKIIIRDCCSFEGLDEY
                     FFRVCILKPNENKLLISSLKAIFK"
     gene            complement(38178..39386)
                     /locus_tag="KRH23_001283"
     CDS             complement(38178..39386)
                     /locus_tag="KRH23_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dicarboxylate/amino acid:cation symporter"
                     /protein_id="HHS5224570.1"
                     /translation="MKKKIGLVPKLIIGIIVGILIGSYAPEIIVQILVTVSTLFSAFL
                     KFVIPFIIIGFVTAGIADLATGAGKLLGITTGIAYGSTLIAGLLSFAVSTLIFPNFID
                     ASVASQIGDPEAGMLAPIFTIPLEPMVDVTAAIVFAFVMGLGISALRNHGKGETLFNF
                     FQEFQGIVTKTLSTVIIPLLPLYIAGTFANITIAGEVWTILGVFWKVYLVVIPLHFVY
                     MACQFTAAGVFSGKNPVRMLKNQVPGYLTAIGTQSSAATIPVNVGCAEKNGVSKQIRE
                     FVVPLCATIHLSGSMISITGFTTAVLMMNGMPHGIGVLFPYIAMLGIAMVAAPGAPGG
                     AIMSALPFLPMVGIPSDGGLASLMIALYLTQDSFGTACNVSGDNAIAVVVDKINDGMS
                     KKGNKEEQSA"
     gene            complement(39547..39936)
                     /locus_tag="KRH23_001284"
     CDS             complement(39547..39936)
                     /locus_tag="KRH23_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YkvA family protein"
                     /protein_id="HHS5224571.1"
                     /translation="MEFLKIIINIVLDILKKILVRFKNAKFGLVFVFDLLKLPDFMTD
                     KRINIVDKIKVISVLIFTISYFVSGVDIIPEMIAGAFGFIDDAIVLIWSIGIVNEEIN
                     KYRVIAKKDKHSNIIENVEFSIKDEEE"
     gene            complement(40040..41041)
                     /gene="asnA"
                     /locus_tag="KRH23_001285"
     CDS             complement(40040..41041)
                     /gene="asnA"
                     /locus_tag="KRH23_001285"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004071 - aspartate-ammonia ligase
                     activity [Evidence IEA];
                     GO_process: GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HHS5224572.1"
                     /translation="MSTIIPKDYKSSLNVIDTQIAIKKLKDFFEMRLSNELNLIRVSS
                     PLFVLPETGANDNLNGEKAVSFDIPFMNKNAEIVQSLAKWKRLALKKYGFEVGSGLYT
                     DMNAIRKNEELDNIHSLYVDQWDWELVIDKSSRNEKTLKDVVKRLYGVFKDTEIFVCS
                     MYEGIKEILPEEITFITSQELEDMYPELSPKEREDKIVKEKKAVFITQIGKTLISGEK
                     HDGRSPDYDDWELNGDILFYNPVLDSALELSSMGIRVDEESLDRQLKLAGCEERKEFD
                     YHKMLLNGELPYTIGGGIGQSRICMYFLQKAHIGEVQVGVWPQDMIQNCSSAGIELL"
     misc_binding    complement(41100..41355)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(41489..42679)
                     /locus_tag="KRH23_001286"
     CDS             complement(41489..42679)
                     /locus_tag="KRH23_001286"
                     /EC_number="4.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0047804 - cysteine-S-conjugate beta-lyase
                     activity [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MalY/PatB family protein"
                     /protein_id="HHS5224573.1"
                     /translation="MSKYNFDRVIDRVGTDCVKWDFRTNCSTKAQKDGLPFWIADMDF
                     ECAEPIIEALRKKVEHKIFGYSSNDSDKYFNAVCDWYKRRFNWEINRKDIIFSPGVVP
                     AVAILVRILTNSNEGVIVQKPVYYPFEAKIKSNNRDVVNNPLIYENGTYRMDYDDLEE
                     KAKCSNNKVLILCSPHNPVGRVWREDELKKVVEICKKYDLWIIADEIHSDLIRKGFKH
                     TPLQSLCPEYKDKIVTCIAPSKTFNLAGMQLSNIIVNNDELKKKYQEEVTAVGVATSP
                     NPFAIVATIAAYNESEDWLNELNDYLDNNIQFIDEYLKENLPKVKLVYPEGTYLAWLD
                     FTAYGLNEVELEDLMFKKANVLFDEGYIFGKEGIGFERINVACPQSLLKECMDRLKTI
                     FENL"
     gene            complement(42960..44081)
                     /locus_tag="KRH23_001287"
     CDS             complement(42960..44081)
                     /locus_tag="KRH23_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 peptidase aminoacylase family protein"
                     /protein_id="HHS5224574.1"
                     /translation="METNKDYIEYVHKVYDYLHTIPEKGFEEYKTSEFVLKELEKMGF
                     ENINKGVAGTGIIVTIDSKKEGPVFAIRADMDALEFIIDGEKKMIHACGHDGHTSMLL
                     TAAKLIKERNLVKRGKLKILFQPGEEKLYGALRVIDSGLLDDVEEMVGMHLRPGQDCR
                     LGKAIPAMYHCASCIMEFTIKGITCHGSKPHLGVNAVDAVCLAVNAINAIRVNPAIPN
                     SIKVTNISVKGETYNNIPDEAFMALDIRAESNDIIEELKEKAIHAVKTAVSSINAEAV
                     LISKDGVPAAEFDEELVNLAEETIKDVLGADASIGIFKNSGGEDFHYYTQKLKCKTTY
                     IGLGADATPGFHNPNVTFDTKALEYGVDIWCRLVEKRLG"
     gene            complement(44142..44627)
                     /locus_tag="KRH23_001288"
     CDS             complement(44142..44627)
                     /locus_tag="KRH23_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjiG family protein"
                     /protein_id="HHS5224575.1"
                     /translation="MSEVAKKEVKVKKGNVIDAFIGGARNGFQISTNSMAPNVIFGFA
                     IISVFNLTGLLDVIGTIFTPVMSIFGLPGVAATAIMTIFISMGGASGVIAGLFTAGQI
                     SQAHVAILLPMLLLSGAQIQFMGRLLGTAELKTKYYPHMFVIATLNGCIAMLIMNYFV
                     V"
     gene            complement(44629..45297)
                     /locus_tag="KRH23_001289"
     CDS             complement(44629..45297)
                     /locus_tag="KRH23_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside recognition domain-containing
                     protein"
                     /protein_id="HHS5224576.1"
                     /translation="MSKLESTTEKVEVKWYGYVALILGALFFSGIFKDAPGPLKVLDF
                     NNVLGSFGTLGTINDGVGTLAANFRGDGGTGPRDGWLYALTLIPSVMFALGVVRVIDH
                     LDGMKAAQKLLSPLLKPLLGLPGFAGLTLIASLQSTDAAASMTKELKDDGYIDEKQKA
                     VFCAFQFSGASAITNFFASGAALFPFIGDVPIFIPLALILIMKFVGANLLRLYLNKFD
                     KGEA"
     gene            45687..47711
                     /locus_tag="KRH23_001290"
     CDS             45687..47711
                     /locus_tag="KRH23_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54 interaction domain-containing protein"
                     /protein_id="HHS5224577.1"
                     /translation="MDKKKLILITYDKLNSDHYKEELTNFFGDEIIIETQNILDGIKE
                     NLEGDVVLSLSPLTSNFLIKHFKEDIEIIHGTKALSKLGYEKMMKLPPGTKSLLMTTN
                     KTSAFEMATYLYKIGINHIDFVPTYPDCDEIYDLDTAITPGQIRFIPKYIKNIVDLGW
                     RKISLDTYMSLLVVLKLKNEKFIEKLYKLSKETLSHDFLNTSLDNISKLKTILYMTID
                     EIGDGLIFFNTFNKVTFVNKSLLNMLELDEKLIKSPSLMEYMPKSFLDKITKNLNIDN
                     MIIYIDEIDKKFILSKKPFYLYKNIEGCLITLKDVNNIEILEQKIRSDSVKRGYVAKY
                     KFNNIIGSSSIIKDCIKKAKKMALTDNPILITGETGTGKEAFTQSIHNHSNRKNKPFV
                     AINCASLPSELLESELFGYEDGSFTGAKKGGKKGLFELAHTGTIFLDEIGDMPHDLQV
                     KLLRVLQEKEIRKIGGTSIIPIDVRILAATNKDLEKLIIENKFRIDLFYRISMFTLDL
                     PPLRKRLEDIPLLLESFLKELPYKNIKLDKSLLEALNSYTWMGNIRELRNCVEYMAYM
                     GSNYLTINDLPQNISSKLNNNHMSSNMSIFNDLSQYDKNICISILKSLHMKPMGRTKL
                     MKFMEYNVTEYEVRNMLEYLTRNGYLISSKGRKGSSVTEKGIKIIENNII"
     gene            complement(47941..49128)
                     /locus_tag="KRH23_001291"
     CDS             complement(47941..49128)
                     /locus_tag="KRH23_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3798 domain-containing protein"
                     /protein_id="HHS5224578.1"
                     /translation="MLRKITAFMLSICLIIGLTGCSLLVGKKDKEKIIDDFKVAVVTQ
                     PLSENKVQYNMVEEMAKEYEEENKIDKDKDGQTKVKQTIKHVVLPENFTSNIDSAINK
                     IVKLADDKEVQAIVVSTDQAGLLPALQKVKEKRPEIITISAPMGDDKNQLSQFVDVNL
                     GVSAEERGKVLAERSKEMGAKAFIHYASTDDLKDVNIAKRLEMIKETCKNIGLPFVQV
                     NTPNINTEEDKNKVKQFLNEDIEKQVKKYGKDINVFGVNEYMDEVILTKALELKYIVA
                     EQSNPSPIQTYPSVMGLKISEKDAQNYDKINDMISEKAKAFGMSNRLGGYPMPMDAFL
                     PSVAIYLATEMVKQDLTQEDVCDPDYLEAFTELRFGIGSEFTPLTEVLYNYQSVILSQ
                     LIY"
     gene            complement(49330..50601)
                     /gene="brnQ"
                     /locus_tag="KRH23_001292"
     CDS             complement(49330..50601)
                     /gene="brnQ"
                     /locus_tag="KRH23_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015658 - branched-chain amino acid
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015803 - branched-chain amino acid
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HHS5224579.1"
                     /translation="MRDIFIVGFALFSMFFGAGNLMFPPFLGMESGKDWLIPLIGFVV
                     ADAGIAMLVIIATARCKGSMDDVLRRAGKGLARVMSVAALACLALLVIPRTCATTYEM
                     GIMPIFGDHGPVAKAVFSIIFFGLTLAFTIRSSKVIDIIGKYLTPALLLVLFVLIVKG
                     IISPAGPMSPEHMIDKNLFGEGISQGYQTMDALGAASMATIMLMSIIAKGYTSDKDQI
                     GMTIKAGFVACVFLAVVYGGLTYLGATVSTLYDTSIPQASLLVEITSILLYGQVGKVI
                     LGVIVALACLTTSTGLTASISTYFEGISKASYKQLVIGICVASMLISNLGVDSIIAIS
                     VPILQTIYPVLLAIVVMELAGKHIKNDNAFKGAAYVTLVISLLSAINGMTGAVPFIQS
                     LPLAGLGFNWVIPAILGGIVGNFIKSNKQVA"
     gene            complement(50742..51395)
                     /locus_tag="KRH23_001293"
     CDS             complement(50742..51395)
                     /locus_tag="KRH23_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HHS5224580.1"
                     /translation="MTKIIKVQKPKFTGELEIIENLEDILEDIFNDEKIFNKIIENEV
                     ISDLDSVRVSFESCIFRNVSFENCNLKKIDLLDVVFENCNLSNTFFDGGSIYRVEFKN
                     SKLIGVRFDDCILKNVLFKDVLGKYSNFSFSKFKIVSILDSNFENSVFQEVKGDNLVF
                     EYTNLKKANFNGTKLSGIDFTTNNIEGIEIGIDDIRGAIFDVSQAIDLTKLMGIIIK"
     regulatory      51724..51825
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            51898..53241
                     /locus_tag="KRH23_001294"
     CDS             51898..53241
                     /locus_tag="KRH23_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015851 - nucleobase transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HHS5224581.1"
                     /translation="MVPNTNNVQPGGNNSSLSFLDKMFKFSERGSSLKTEVIGGVTTF
                     LTMAYIVFVNPAILSEAGMDKAALITVTILATAIGTLIFAILGNAPFALAPGMGLNAF
                     FTYSLVIGAGIPWQTGLGVVFLSGCVFFTLAVTGLRKTIADAIPRELAVASSAGIGLF
                     LAFVGLKNMGVIIANPDTIVSLADFTPTVLIALFALILMAILEYKKVKGGILISIVVA
                     TIISVIFGFVELPTAIISTPPSIAPVAFKLDIVGALKFSLIGPIFSFMFIDMFDSLAF
                     LITCCKQMGLEDENGEIKDLGRMLYADVSSTLIGSFLGTSTVTTFGESASGIAAGART
                     GLASIVTAALFLATLIFTPLLGIVPTYAAAPALVMVGVFMFESIKQIDFADSKIAVPA
                     FVTVLLMPLTYSISIGLCFGFISYIIMHVVAKETDKISITLWIIGLLAVVNLVLS"
     gene            53388..54752
                     /locus_tag="KRH23_001295"
     CDS             53388..54752
                     /locus_tag="KRH23_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HHS5224582.1"
                     /translation="MSQLLIKNAYLITMNADREVYETGSILIENNIIKNVGKFDINIV
                     DKDAEIYDAKGKILMPGLVNTHVHLSQQLGRGLADDVVLLTWLRERIWPYESSFNYDD
                     SLISSTACCVELIKSGVTTFLESGGQYVDAMVEAVDKTGLRACLAKSVMDTGDGLPEA
                     WQKTTDEEINTQLDLFHKFNNTSNERIKIWFALRTIFNTTEELLVKTKELADKYNTGI
                     HMHIAEIADEISFVKQNNGVGTVEYLDKLGVLGPNLLAAHTVWLTHKEIDLFRLHDVK
                     VSHNPAAAMKVVLGFASIPEMLEKGIPVSIGTDGAPSNNRMDLMRDMYLTSLIHKGRT
                     LNPTVVPAEEVLEMATINGAKCALLEKEIGSLEVGKKADMIILNPDTIHCLPMHNPIG
                     NIVYSMTSENVDSTICDGKWLMKERKVLVVDESELLNKVKKQASKIKDKAEVKIPSKF
                     KIIK"
     gene            complement(54930..56795)
                     /locus_tag="KRH23_001296"
     CDS             complement(54930..56795)
                     /locus_tag="KRH23_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIRAN domain-containing protein"
                     /protein_id="HHS5224583.1"
                     /translation="MENVFKRLQEFNGYDGYKESFEMNYLCIYESIPLREQVELANNL
                     VDEILNMYKSESNEIYLLEDSNSKSLICYFEIFMKKINTLVKEMIIDEKWLYKLTKEL
                     IYKSKKVEYVKLGLVLSEKYLNVENLREVVDTFSKSGEYVFYLSNTIKKLEFYNTYLF
                     NLSKKATGSIKVFAIVNMENLDSKINSYLIEDGYKDTKYERLLMNYIISIVDLNEYLE
                     KRDLDKEKINNLACLICNYLLSVEFKYIGNKLELVNRFLPTVVNYGTNFESLYSIFLI
                     AINVLKDENIECNKIEFEKEINDILLSEKWKNIYFEALRDASGKTEDIIKMSEIYDVN
                     LSFDDLLPYLNRDIRDFEVYWHISKKGTTSSRLKLLNFFEETFKIDDLIGKMKDIEKD
                     KLTQEYYDDMLFFIVLKGSKSLYPEGKNISLKGIFGNINEVRKESINILKRYREKLSL
                     EELKIVKEAYEKEKNIILKDELRRVLYESNNLKKEFVNIEKIKVDEHGKDIYLTSIAV
                     AGSRFRNREYLEKELEKSKIYYLTREKDNLYDEKAIKIVGETGYVIGYVPRKENYILS
                     NLLDGGKLLYCRVTEYNLYEDCIYANVYLSYKDVIETVENSLKMVLDKSRIKLIN"
     gene            complement(57031..58248)
                     /locus_tag="KRH23_001297"
     CDS             complement(57031..58248)
                     /locus_tag="KRH23_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HHS5224584.1"
                     /translation="MNNKKYYPTAIALYFSYFLLGIGISILGQYKPEFSSMWGAKTLS
                     DGTLDVSIVLAVIAALGLGRLISYPFAGPISDKYGRKVSGLIGNFLHAIFFVGIVFSP
                     NFYIAYVFAIIGGAANSFLDTCVTPSCMEIFASLGTIANMFTKFTIALAQFLLPFIIG
                     FVAANSISFKVIFIVTAILIVVDAILIAVLPFPPANNVIDNKGKTVKSEKMKFTPTSI
                     ALVCIGFTCTSTFVLWLNCNQELGKLYGMADPTKIQSFYSMGVICAVLITSLLIKKYI
                     KPIRILVIYPIIALLMLLVVYFVQTPTICMLGGFVIGYSAAGGVLQLTTSTANEMFPT
                     NKGKITSIVMIASSIANYVILNIAGIITKSGGVNGPKYVVLFNVAITFVGILLALFVN
                     MRYEKEKVYDYDV"
     gene            complement(58448..59311)
                     /gene="aroE"
                     /locus_tag="KRH23_001298"
     CDS             complement(58448..59311)
                     /gene="aroE"
                     /locus_tag="KRH23_001298"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004764 - shikimate 3-dehydrogenase
                     (NADP+) activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0019632 - shikimate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HHS5224585.1"
                     /translation="MEISGRTGLFALIGTPVGHSKSPVMYNYSFKKLDLDYRYLAFDI
                     TVDKVKEALLAIKTFNIKGANVTMPCKSAVTEYMDELSPAARIIGACNTIVNDNGKLV
                     GHITDGVGYVRNLKENGVEVKGKKITIMGAGGAATAIQVQCALDGAREISIFNPKDDF
                     YKRAEQTVENIKKDVPECVVNLYDLEDTNKLYEEIQSSNILTNATLIGMKPYDNETNI
                     KDTSVLRKDLVVTDVVYNPKKTKMIEDAEANGCKAIGGLGMLLYQGAEAFNLYTGLEM
                     PVEEVNELCFK"
     gene            complement(59393..61315)
                     /locus_tag="KRH23_001299"
     CDS             complement(59393..61315)
                     /locus_tag="KRH23_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HHS5224586.1"
                     /translation="MKISSMFTPIRIGSMTVPNRFVVPPMGNNFANTDGTLSETSKAY
                     YLERALGGFGLITIESSVVDKKAKGGPRKPCLYDDSTIDSFKNVIDACHDAGSKVSIQ
                     LQHAGSEGNEKVAGHPLKAASAIPASNGRNTPLAITTEEIYELIESYGDAALRAQKAG
                     ADAVEVHCAHGYLVSSFISQRTNKRVDEFGGCFENRMRLPRLIIENIRKKVGNSLAIL
                     CRINSTDDVPGGIDVHDSSVIAAYLEDCGIDGLHVSRSIHIHDEYMWAPTTLHAGFSA
                     ELVTEIKKAVSIPVITVGRYTEPQFAELMVRQGRCDLVAFGRQSLADPEMPNKAKNGK
                     LDEMIPCIACLQGCVPNMFQGKPIACLANPILGHEAELKPAEISKEVLVVGGGVGGML
                     AAWVCAKRGHNVTLVEKSEVLGGQMRLAAYPPGKGDITNLVRSYISKCNQYGVKICTN
                     TEATVELIKEKSPDVVIIATGATPLVLPIPGINDSGLIHAVDLLDGKKSCGKKVLVVG
                     GGMVGCEVAAFLGEQEHEVTVIELREEVGADVISEHRKFLMNDFENYNIHTITGAKVS
                     KFYDDGVDYLLTDGTEHDLKGFDSVVLAMGSRNYDPLSEVIKEVVKETYIVGDAVKAR
                     RALDATKEAFEVALNI"
     gene            complement(61394..62242)
                     /locus_tag="KRH23_001300"
     CDS             complement(61394..62242)
                     /locus_tag="KRH23_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase family
                     protein"
                     /protein_id="HHS5224587.1"
                     /translation="MNNQKNLNIPITISSYTLGTEVSFRDRVRIAKEAGFDGIGLRAE
                     NYIDAKNAGVTDEEMIAILNEYDMKVTEVEYITQWGREEDRTEAQREKEQNVYHMAHL
                     FNVKHINCGLLEMIPEEQIITALGELCDRAGELIIGLEFMPYSGVPDLATAWRVVKGC
                     NRENAMLILDTWHWARAKQTAEDLAPVPADKIVSIQVCDVLETPYEKLRDESLHDRLA
                     PGEGYGNTEEFVKIIKEHNISPRVIGAEVISDSLISKGLSTAAETVFNATKKVLDKAW
                     SEVSPK"
     gene            62655..63536
                     /locus_tag="KRH23_001301"
     CDS             62655..63536
                     /locus_tag="KRH23_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HHS5224588.1"
                     /translation="MNLYHLRYFVTLAHLEHYTKAAENLSITQPSLSHAISLLENELG
                     VALFEKEGRNIVLTKYGKIFLKDVEKSLEILDSSVKSLKITGTGEGQIDLAFLRTLGT
                     DFIPDIVHKFLKSNPAKSIDFKFHTGVTTDIIQGLRERKYDIAFCSKLEKEKGIEFIP
                     VAKQDLVLIVPYSHPLAAKDTIDLKETIPYPQIVFNQRSGLRYIIDDMFKKINQQPNI
                     VYEVEEDQVIAGLVAKNFGIAVVPNMNMLSFTKVKVIQIIHPSWERNFYLAFIKDRYL
                     PPAIKNFKNFVIKNAQL"
     gene            complement(63744..64607)
                     /locus_tag="KRH23_001302"
     CDS             complement(63744..64607)
                     /locus_tag="KRH23_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3800 domain-containing protein"
                     /protein_id="HHS5224589.1"
                     /translation="MLSSYVKRVSKIIKKKYIMFIDESGRADINHEDPFTLTGVIFEY
                     KYAVSQGDYVCSLRKEMDAFKEYCFGTSNIGIHLTDISRKSRAFEKFDDSQIKLFYDE
                     LPLFLSRLECTIISVTVDKARLKKYYAPSKEPYVVAFIHVLQNFYSFVNNETVESARI
                     VIESRDDVSNLKVQKAFFDVFNNGTIYLDIDEELRDKVKGFIIAKKEDADYREGLEIA
                     DILCNPLSRARRGLIEANPKCMQYGEKNKIFKSVRNKIYTPTSVNDIRNWGFKEVPIV
                     EPVGPWLEKMR"
     gene            complement(64762..66696)
                     /locus_tag="KRH23_001303"
     CDS             complement(64762..66696)
                     /locus_tag="KRH23_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp22"
                     /protein_id="HHS5224590.1"
                     /translation="MKKSLKKYLVLALTLVLVFACGVPESSAASKHVIIVNSRKNTLG
                     YFVNNKLVKEFRVATGKKGSETPTGKTKVVNKIKNRPYYKGNIPGGSPRNPLGDRWMG
                     LALKGTYGDTYGIHGNNNESSIGKHISGGCIRMHNKDVRWLFDQVPVGSDVIIDYSND
                     SYVKIAAKYKINLNQTGWKTENGKKYYVKSDGTYQKNSWLKVNGKMYYFDASGVMQTG
                     WKTINNKKYYLGTDGARVSGWKVIDGKTYYFNSDGVMQTGWQEKNGKKYYLGSDGLAV
                     TGWQEIDGNKYYFDKTGIMQTGWQQIDGKSYYLDKDGKMLTGSQKIDGKDYTFNEDGT
                     INPTWDTIIGANRFDTAKKISSVGNWNADSSDTVILVNGNAIADGITATPLASSYDST
                     ILLTNTANLPTETVEEMKLLAPKTVILIGGENAISSKLEQEIKTTFNTETKRIAGQDR
                     YQTATRIAEELGNREEIKTAYMVSGNGEADALSVASKAGEEKQPIILVNKDGITEESY
                     KWLTERKLENAYFIGGPSAINDSVIAKMNDITTEDISRNRIYGDSRVDTNAKVIEKFY
                     GDTDLQAVLVSKSDALVDALSAGPLAVKLHSPIVLMDNSGLSSEQQRVFANKKVETPY
                     QIGGGVSYIVMDKLMDILAK"
     gene            complement(66808..67821)
                     /gene="galE"
                     /locus_tag="KRH23_001304"
     CDS             complement(66808..67821)
                     /gene="galE"
                     /locus_tag="KRH23_001304"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HHS5224591.1"
                     /translation="MAVLVAGGAGYIGSHTAIELLESGYEVVIVDNLSNSNSIVVDRI
                     KELSKKPVKFYNIDIRNKDEMHVVFKENNIESIIHFAALKAVGESVEKPIEYYSNNLI
                     STLNLFELMREYGVKKFVFSSSATVYGDPHTCPILEDFPLSVTNPYGRTKLMIEQMLV
                     DISKADKSLDIALLRYFNPVGAHKSGRIGEEPNGVPSNLMPYITKIAVGKLKELSVYG
                     NDYPTHDGTGVRDYIHVLDLAAGHVKALQKLEENPGLVVYNLGTGKGYSVLDLVKAFS
                     KASGKEIPYKIVGRRAGDVAMCYADSSKAEKELGWKAKYELEEMCEDSWRWQSMNPNG
                     YEE"
     gene            complement(67845..68720)
                     /gene="galU"
                     /locus_tag="KRH23_001305"
     CDS             complement(67845..68720)
                     /gene="galU"
                     /locus_tag="KRH23_001305"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003983 - UTP:glucose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0006011 - UDP-alpha-D-glucose metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HHS5224592.1"
                     /translation="MQMTVKKAIIPAAGLGTRFLPATKSQPKEMLPIVDKPTLQYIIE
                     EAIESGIEEILIITGRNKKSIEDHFDKSVELELELEQKGKTEMLEMVRDISNMVNIHY
                     IRQKEPKGLGHAIYCAKSFIGDEPFAVLLGDDIVDSDVPCLKQLIDTYNEYKTTVLGV
                     QKIAKEDTNKYGILDVKHIEDRVYKVKDMVEKPAIEEAPSDIAILGRYIITPAIFSIL
                     EKQTPGKGGEIQLTDALQTLGKQEAIYAYNFEGRRYDVGDKIGFLEATIDFALKRENL
                     KDDLMDYMRKKVSEK"
     gene            complement(68912..69232)
                     /locus_tag="KRH23_001306"
     CDS             complement(68912..69232)
                     /locus_tag="KRH23_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224593.1"
                     /translation="MSSKYNVWTFNYEFLGLDSGDEKNNEVYYEIDLDEILNENYIDE
                     DIDSGLDSDGNSILGELISEMDIDEDVSVDMTYQELEVDLEDLDSYLDEDIDSDIKGI
                     LDEI"
     gene            complement(69222..71213)
                     /locus_tag="KRH23_001307"
     CDS             complement(69222..71213)
                     /locus_tag="KRH23_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224594.1"
                     /translation="MLKLGEKIIYELSDGFELSGISRYSKEYKKLHITNLGNIIISKS
                     DEVNEDTGVKYIYSFSDNKEKLEAVLEDSQIIVYGNNLPFYIKSENSSKNVTANLTMK
                     ITLDEYDLICKSQREFIFYLKDNMTILSLDDNKFYMGGINKDNEKFIFISGKNRFEIN
                     FDDIERYILEDKRVSLKGYFHMEREGIIVRSVSIFNNNIDSVVPSDLNERVKDNQKIG
                     NLPKDCEIVFCKISGNIDGFDYKNTNMLLVKYQDQLIFINKKSKKTIVKSAKDNCSKL
                     NLGEDIILYDNKNVFNLHINDKNREIMQIDDLKDIENEIVGYTLKHAPFFIQEDFDSL
                     TILKSFQKEIISIKNSDIKDIVINKELENENSNFVETEIKFNNQKVLLNLSKSMVQKL
                     MQDVFIYAKQPLLKENSIEVIYKNWSKAMNDMIIFNFFGNIYYMKSEFDKILEKELND
                     EIRIEVINSLYKQIQEQRNNLDLLSAYMPRILENQEIDLFEKYNTKLDVQVFKQIKNL
                     LSDLSYNISSYLNEVEKSLDNIIFVISGEDKKKYNYRMLKESESASLDVFLKQAISRL
                     NHLVENMYPYYVDETSREMFKLFELLWKNYRNIDDNSIKEILFERITNTYVFKQLTLN
                     NSTKERRKDIIEKIYNSVDYGTNKLDENMFFTGGIKYVK"
     gene            complement(71336..73879)
                     /locus_tag="KRH23_001308"
     CDS             complement(71336..73879)
                     /locus_tag="KRH23_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042834 - peptidoglycan binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SPOR domain-containing protein"
                     /protein_id="HHS5224595.1"
                     /translation="MKVLSENNIIRNTVLNVTASFLKQESKINEKLDGVLEKKFEKVE
                     FNEAKYAELLKFNILFYKTLARNTEPLIGKWIVDKYIPEIDELEKDLELTTAKCRKYV
                     NKAMKEGLDSLKANDLNSFLAYDKMELSERRRRLEKDYKVLNLYKDLLNISLRKISLE
                     KKECGDLFLKNQADAKRELKREIIFCVNKILASNKDVVPNNVEENNEQDKVEIKATEI
                     EDLQLGKDNSENDMLLNEIKNSKVKHESKSNDIESKFIDKLNSLNNESVSQTIHNEYK
                     KLCGLEELHSVEGYGFGKEIIKDFACATVVLEFLKRRNRDLIEGAMRLTIIGEFGPEN
                     FKEFVDYVIKNKTEISEDTWNKAQNLIKDNYSELENHEIASKRTRRNKDIDIEEYIYM
                     IKNADKDICFRSSISIEDDAEEGVKEGIDSNNQDIGDVVEDKDTTDKEYDSNKEDIIE
                     PENKKSKKKAKLFGFIKKDNEEVEQEEENLNDISPDIILDKPVENHQVKSEEIEQNEL
                     KEIKQEEPSQHIEEERSVKIEKPINNNLDEKVSSNNESKLEKESKNLEDKKAKEIKEE
                     KLENEKSVVIPIKKKENSNKKSKNSSKDKYRENKKEMKNYVSDKEDSLDDEEVVSKKS
                     RLKETIIAVVIVVIVGVGYFITVGNNKKNDKENIPKSSTQQQANNKLTEEEKKAQAEK
                     EKKEAEEKAKAEKEAQEKAQAEKKAKEMEAYKDGKGVYYTVYAGSLKVEKTAKETAKE
                     YEAKGISSTIIQENGYYKIKIGDYSQYGEAQEKCNELAKKSIDTYIAMYDKYYDYKLE
                     ELKESAPSLSAEELKQKYEDLRSELKNKSGYREYVKHLDKLYEEIVEGA"
     gene            complement(74157..74491)
                     /gene="rnpB"
                     /locus_tag="KRH23_001309"
     ncRNA           complement(74157..74491)
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="KRH23_001309"
                     /product="RNase P RNA component class A"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00010"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00010"
     gene            74623..75300
                     /gene="srtB"
                     /locus_tag="KRH23_001310"
     CDS             74623..75300
                     /gene="srtB"
                     /locus_tag="KRH23_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtB"
                     /protein_id="HHS5224596.1"
                     /translation="MKKLYRIVINIILVLVILYSGFNIYSKLTKYNHDTKISSELQKK
                     EYKKEDLSKINSDFKFWLSVENTNINYPVVQSKDNSYYLDKDFYKKDSISGTLFMDYR
                     NKSIDDKNIIIYGHNMKNKTMFNNLNKFKDADFFKKNNKIKITLNGKEFLYDVFSAYI
                     VESDYDYLKTNFNNESDYQNYINDITSKSLYKSPIKVNSNDKIVTLSTCTYEFDDARM
                     VIHGRLI"
     gene            complement(75460..75534)
                     /locus_tag="KRH23_001311"
     tRNA            complement(75460..75534)
                     /locus_tag="KRH23_001311"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(75500..75502),aa:Thr,seq:tgt)
BASE COUNT        25399 a        12602 c         8862 g        28720 t
ORIGIN      
        1 attatataga atttaaaaat aaaagaagag tatttcaaat gatttgtata aattattatg
       61 aaaaactctt tttttggtat aataaaatta cttacatata taacatttaa atttataaat
      121 tatcttttta ttttttaaaa tatgtataac acacctatag aaattactat tattactatc
      181 taaagtattt tgctataatc ccatatactc ttacctcaaa aacattcaaa tgtaaaaaat
      241 actacatatt aataaacttt gcccaataat tcctaaaata atatcctaac aatgatttat
      301 gtttttataa tagtatattt ttacataaaa aagtgaacat tgattaacaa agttcacttt
      361 tttataaatt tttatgttat aattcacaat tttatttaat ttgtttcttt tctatttaaa
      421 ctatatctat ctaatattaa tttttcatat tcttctattg gcattggtct agcaaataaa
      481 aatccttgag ccatatcaca acctataaac cttaaaaact ctgcttgctc tacagtttca
      541 acaccttctg aaacaacttt tatatcaagt tgctttgcca tttgaacaat acttgaaact
      601 acaatttgac tcttttttgc atttcccact gttataaaga attgcctatc taatttcaat
      661 acatcaattg gcatatcttt aagcatattt aaagaagaat aaccagaacc aaaatcatcc
      721 atagaaattt taaatccaac agatttcaaa gtttgcatta ttttaaataa tatttttgta
      781 ttgtcaaata ttgcactttc tgtcaattca atctcaatta aatttggttc aatttcatat
      841 tcttttgtta ttctttcaag ctcagaaata aagcctggat tctcaagatg tactcttgat
      901 aagtttattg atataggaaa tgtggggaaa ttttcatttt cccaacgttt aaaattttta
      961 caaacttggg taaatacaaa catatccaat tctgttataa agccattttt ctcaaaaata
     1021 ggaataaata cacctggact tattagacct tttttaggat gttgccaacg tacaagtgct
     1081 tcagcaccta caattttagt agttgataaa tcaaccttag gctgtaaata aactttaaat
     1141 tgttcatttt ttaaagcatc atgcatttct tgttcaatat cacgttcttc tatgagagtt
     1201 tcttttaaat tttcagcata aatctcataa acttttaaat attttctttt tactgtagtt
     1261 tttgcaatca tagctttgtc aagacaggta gaaatatttg tttctccctc ttcaacgaaa
     1321 tatacaccta tggatggaat taaattgagt tctactccca aacttgtttt tatcattgac
     1381 aattttttac gtataagttc acatatttct ataattgact ctctattatt tttcttttca
     1441 aatattatag caaaattgtc atttgaaatt cttgaaaata cagattgctc tttaaatata
     1501 ttcttaatta tctctgctat ttcctttaat actctatctc cttcttcata cccaaaccta
     1561 tcatttacta gcttaaactt atctatatca aaataaatta aaactagatt ctttttctca
     1621 tgagaggata aaaattttcc cccttcaaga ttaaatttat ttgaattacc aatacctgta
     1681 acgttatctt taaaagcaaa ttcttccaat ttttccttac tctttttatg tataaatagt
     1741 atataaattg ttaatgccgt aaagattata atcaacacta cacatgctga taatgtaagt
     1801 tttataatag catatgattt ctcagatata gcagttttag gaacttcaga aaaaagatac
     1861 caatcattga ttcctattgg ggcataactt aaataatatc cttttccaaa catactataa
     1921 cttaatgaac ctgatttaaa gttttttata tttgacttca tattattgat actagatttt
     1981 gatattgaat cacttctgcc aatgtaagaa aataaatttt ctttagtaga gttggcgttt
     2041 ttactgcttg gatttaaaac aatgtcacca ttacttctag ttatataaga atatcctttt
     2101 ccattaaatg taggtacaga aagtattttt tcatacaact tcgtactatg tgtggcaaat
     2161 ataactcctt taacctcatt atctttataa attggtacag aatatacatt aatattacta
     2221 ttggtatttt tatcatcttc tattacatct tttaatttgc ctgttataac cacttctcct
     2281 tgcattgatt ttaagaaata atctctttta gagaagtctt ctatataacc atctgtagtg
     2341 tatgctgtac catttggtaa aataactccc attcttttaa atgaactatt aatagcttgt
     2401 ctttttagta tagaaaggat attatctact tcaaaagact cttctccttc gataaatatt
     2461 gaaattgact ctagtaactt tatatctcca ttaatttgtt tttttaacac attgacgctt
     2521 tgatttgcta tttctgaaag atattgattc gtttcttcac ctaatgtctt attcaacctt
     2581 gaaccataaa tcaaacagga aattgtaatt actaagatac ttatgacagc aattatggac
     2641 aaaccatacc tattattttt tgcatcactt aacattatgc ttcctgcctt tctcgaatct
     2701 atgtatgtat aatcattatc ttatgacaat tattgtaaac attttataat aatacttatt
     2761 tttccatatt tactgtaatt atacaaaatt ataaacttta ttacaacaat aaattaatta
     2821 atatagatat tagtgtttat attattgcat tatctatttt acaattattt acatataaaa
     2881 aaatgtaata tcaaagtgaa acttgatatt acatttttgt tcttgtattt tgtttaattt
     2941 ttatgctaca ttttacttaa acactcattt gcaacttctt tatcatcaaa atgatgctta
     3001 actttaccta taatttgata agtttcatgt cccttacctg ttataattac aacatcatcc
     3061 ttttttgcca tacttatagc ttctgctata gcttgttctc tatcaacaac aacatggtaa
     3121 ttttcttttt tcttgtcaat tccttcaagt atatctttta ttattgcctc tggttcttca
     3181 gttcttggat tatcagaagt tataatacat aaatcagaat atttttgtcc aattgctccc
     3241 atcaaaggtc tcttttcagt atctctatct ccaccacacc caaacacaga aattattttt
     3301 ccttctgcaa attgttgagt tgtctttagt acattttcaa gtgcgtcagg agtatgagca
     3361 tagtctacaa ttacgcttat acctttatca tttggaactg tttcaaacct tcctgatact
     3421 ccattagaaa gtctaaggcc ttctttatat attggtttag gtatgccaag tacatagcaa
     3481 gcagctataa ctgctaaagt attatatact gtaaacattc ctggaactgg tataaatatt
     3541 acttcttcat atgaaggtgt tattaatcta taagatactc catccgaatc tgattttata
     3601 tctctagcca taaaatcagc cttagtatca acaccataag tgtaacaagg tacatttata
     3661 ccttttatat tttcatatat cttttttccg ccttcatcat ctatgtttat tatatttgcc
     3721 atagtagtct taaaaaataa tttttctttt gcttttctat aatcctctaa atctttatga
     3781 aaatctaaat ggtctggtgt taaatttgta aatatgccta gtttaaagtc tgtttcatca
     3841 actctattta gtgccaatga atgtgatgaa acttccatcg cacagtagtc acatccatta
     3901 tccaacatat tattaaaatg atattgtaaa tctatacttt ctggagttgt tgaattggaa
     3961 ataatgtctt tttctccatc aaaaattttt atagttccta taagtccaac tttattctta
     4021 tttaaagtta atatctcatt tagtatagta gttatactag tttttccatt agtacctgta
     4081 actcctataa cgttaaattt ttgagatgga tgattgtaaa aattatcagc tacttttgcc
     4141 atatcttttc ttgtatcttt tacctttata aatgtacatc cttttattgc tacatcttct
     4201 tcaacaagaa atgcacttgc tcccttttct atggcatctt ttatatactt atgaccatct
     4261 gacacaaatc cttttataca tataaataat gtaccttttg taacctttct tgaatcatat
     4321 tgtacattat taatatctat atttaattca cccttgacat tgattatatc caacccctgt
     4381 ataatatcat ttaatttcat aaatgctttc ctccctttaa actctttctg ctaaaattac
     4441 actacatata atattatatt aagaattttt tactatgtga atggttaaaa atgcttgaaa
     4501 cattgcaaaa aatgctctat aattttctat aatataactg aggaaaggtc ttctataaaa
     4561 actatggata ataaaatcgg gtacttaaac gataacttta aaatatttaa tattagagat
     4621 aaaaaagata tacaatttga ataccataat catgatttta ataagataat tatatttata
     4681 aatggaaatg taacttattt tgttgatggt attccctata aactaaagcc ttgggatata
     4741 ctctttatca gcaataatga aatccataaa ccagttatag attcaaatgt cttttatgag
     4801 agaattgcaa tatggattag cccagaattt atgaaaaaaa atagtgatgc tagtagtgac
     4861 ttagaaaaat gttttaaaat agctacagag aataaatgca atagattgcg tttaaatata
     4921 catgatattg aatctattaa gagttttatt gagcaaataa atatttccga atccaatact
     4981 gaatttggaa atgaaatatt gagaaatgca ttatttatac aacttatgat attcttaaac
     5041 agaattttcc taaaaaatga aaatatggaa tcaacagaag atgtttttta tgatgaaact
     5101 attaagaaag tattaaacta tataaattca aatatagatg ataagctttc aatagatagc
     5161 atatcgtctg aattttttat aagtaagtat tatcttatga gaaaatttaa atctcatact
     5221 ggaacgtcta tacacaatta tatagttcaa aaaagattaa ttttggcaaa gtcactaata
     5281 accaatggtc accttatgag tgaagtttgt aataaatgtg gattcaacga ttattctagt
     5341 tttgtaaggg catttaaaaa aaactacggt gtatctccta aaaattatat aaacaataaa
     5401 aatcctttgg atattactct tttagatgaa tagataattt atgtaaattt tattttaata
     5461 aaacttgaag tattagtgta tttatcttac taatacctca agttttttaa tgttttaaaa
     5521 tatatcaaaa tataatgata tatatttcta ttacctaaaa tatatattaa ataaattgca
     5581 tgttaactga acctatttat atatttatta aatctcacat aacttttagt tacactatca
     5641 tatagctatc ctattttttc aatatcatct cttaatatac ttactctttt ctcctctttt
     5701 gctgtggtta ctcctttttt aatgcttaat ttctgatttt gttctaaatt cgtaaatact
     5761 acaggactta ttgttgatag accatttttt tcaatatatt ctaagtccat tttaactaat
     5821 ttttctcccg cttttacttc atctcctaca ttcacaaata cttcaaatcc atttccttct
     5881 aaatttacag tttctatccc taaatgtata agtatttcta ctccactttt tttggatttt
     5941 attattattg catgcttagt tggaaatata actccaatag ttccatcaac tggtgaataa
     6001 atcaatccat cactagattt aattgcaaat ccatccccca tcagtttact tgaaaataca
     6061 gaatctggca cttcttctat atctaatatc tctccatttg ttaatgaatc aatattttct
     6121 actaaagcat tttccatatt tgcaacttcc atattttttt tcactttatt tttatcaaca
     6181 tttttagtaa cagtactttc aacctttgtt tttccctcta ttatatcttt tatatcagac
     6241 tttattgaat ccgattttgg tccaaatata gcttgaacat tgttgccaat aaccataaca
     6301 cctgctgctc caagtgattt caatttttct ttatctactt tatttatatc atttacaacc
     6361 aatctaagtc ttgttataca cgcatctagg ctctttaaat tgtctttatt tcctaaagca
     6421 atcaaaatct ctgatgctaa ttcattctta gacatttcaa tgacttcagc gttagtttct
     6481 gactcatctt ctcttcctgg tgtctttaaa ttaaattttc ttatcataaa tctaaataca
     6541 ctatagtata atactgcaaa accaatgcct accaagatag ccaagtacca tggagttcta
     6601 ttaggaagaa caccaaataa taagaaatct attaatcctc ctgaaaatgt gaatccaatt
     6661 ttaactccta ataattgcat aattgcgtat gataaacctg aaaataaaca atgtattgca
     6721 aataatactg gtgcaacaaa taaaaacgca aactctattg gctcggttat tcctgttaaa
     6781 aaagaggtta atgctgctga tgccattata cctgctacaa attttttctt ttctggcttt
     6841 gcttcatgca ccatagcaag agctgctgct ggaagaccaa acatcataaa tggaaatgca
     6901 cctgtcataa aagtacctgc tgtgaaattt actccatctt taagttgagc aaagaatatc
     6961 ttttggtcac ccattacaag ctcaccagct ttatttacat attctccaaa ttgataccaa
     7021 aatggattat ggaaaacatg atgcaaacca aatggtatta atagtctttc caaagaacct
     7081 tccataaatg ctgctagtgt ttgatttgct tctataacat tttttgagaa actaagtaat
     7141 ccctcttgta ttggaggcca aataaaagac aatataattc ctattgctat agcaactaat
     7201 gaagtaacga ttggtacaaa tcttttacct gcaaaaaaac ctagatactg aggtaattca
     7261 attttataaa actttttata aagataagca gccactatcc ctataataat gccaccaaat
     7321 acccctgttt gaattgttgg tattccaaca atatttgcat acatagaatt gtctaccata
     7381 tcttctgtaa cacctgccat aacacccata gatgtattga gaattaaaaa acctactatg
     7441 gctgccaatg ctgcaacacc ttctccttca gttaaaccaa cagctacccc aactgcaaat
     7501 ataagtggta agttattaaa tataatttga cctgaacttt ccattatact tattataagt
     7561 tgaaatgtag gattcgccaa agctggaaaa tgagccaaca atgcgtctcc tgctaaagca
     7621 ttactcacgc caagtaatat acctgctgca ggaagtaatg caactggtag cattagagat
     7681 tttcctactt tttgtaaaac accaaatact tttttcattt acttttctct ccttattatt
     7741 ttatattttt ttaaataaaa aagacttaag tttataaaaa gttacattag tatacttaat
     7801 tctaaaatta aacttatgtt aatataaata aacctatatt aacctaattt cagaattaaa
     7861 aataaactat tataattttt ttataaacat aagtcttgcc tgcattatca gtaacaatct
     7921 taatgtttta aaattattat tttatattaa attttaaata atatattaaa attgaacata
     7981 atatattaaa tctatacatt ctgtattaaa ctactcttta ttataaattc agtacagata
     8041 taactctttt gatatgtaat gttaaataaa gtagttcatc ttgacttaca tagtaatcat
     8101 aattcttttc tacatgagtt tttattttat atgcacaatc ataatccttt tcatacttta
     8161 ctttaattat atctataatt tcattatttg tatcattgat tttttctttt tttactaatc
     8221 gttttgcaaa gaattttaaa tgagtcagaa gcctatcata atttatatca tcttctttaa
     8281 attcaactct ataataatat cttataatat ttagtatgtc ttttacaatt ttagtaatta
     8341 atagtgattc ctttgaactt cccttatagt ttgaatttac tatatgcatt gctataaaac
     8401 cagcttcatc tactggaaat ttcacatcaa attctttatt tatataatct acagcccatt
     8461 tcccaatctc atattctttt ttatgtattc tttttatctc atgtagtaaa tcattcttta
     8521 tagttatgtt ttcatgatat cttttaattg caaatgcaat atggtcagta agtgctacat
     8581 aaatatattc ataaagctta gtattcaaat tctcctctgc ataagcaatt atttcagtac
     8641 taacctcaaa aaatttctca tcaacctggc ttgctagttt actaatttta tctaaaaagc
     8701 tttcatcttg tattacaaaa gttctttcaa ttttactttt atctatttct tgacctttct
     8761 ttttttgaaa cccaattcca caacctgtta atattaattc tttttttata ttttcatcta
     8821 aaactaatac aacattatta ttataaattt gttgaataat cataatcaat atctctccca
     8881 aaatacaatt tcccttattc ataaaaaaat acctaaatta agatacaatt cacctgtata
     8941 ccttaaccta ggtattgcct gcttaccagt aacaatccag cttgttaacg cttatatatt
     9001 gtattcaatt tatggtttta ttctattata aataaatata tatgtcaagt aaattattga
     9061 aaactatttc ctatttttta gtattaattt taacatcaaa aatcaaattt tattccatta
     9121 tatttatgat tctatcatca tcatttcatc atagagaata ttttccaata actctttagc
     9181 cacttctctt gatatttgct tagtttcaac taattgttga acactgtctc tttgactttg
     9241 tatcgccatt actctgtagt attctactct tgcctcaaac ttatcatcat tttgaatctt
     9301 tctagtaatc caattcaaat aacgattata gaatctgatt gctattaagg cctcatgtct
     9361 gttatcttca tcagtatttt tatttataaa tgatatagca gttttagtag aaagtgcata
     9421 tgcatggtga aactctttga ttatttcttt attctcagat actatttttg taattttttc
     9481 ttttacttct ttctttactt ttctatttat aatccacatg cttattttta attttacaat
     9541 tttaaatata gatttttgaa cagattttct tgattttgta atataaaatc tatacaattt
     9601 aaaggctcta tcagaaattt taccatcttc taatagtttc aaaacagcta ataatccctg
     9661 ttggtctgct tctgcaatca tcatacttat aagtttatta tctggagtat ttagtattcc
     9721 tttttctgag tctaccaact gttcatttaa atcatgtata actggttgta cttcttgtgc
     9781 tttttcatta ctaagtttta aaatggcttc tttcaaaatt agtttatatg cctctttatc
     9841 agataataaa ggttctgact cttgtacgtt attttttaat aatcttggca gtaaaactgt
     9901 tgccaatact aaacttataa gaataacttc tgatgatata aataaaacag tatctctcat
     9961 tggaaataca tctttatcag ccaaataaaa aggtatagat aaggcagttg ctagtgtaaa
    10021 tgtaccatga acaccacaag tagcaactat tagtgagtat ttacatttag aaatactctc
    10081 ttttacaact tcttcatcct taaaacctaa aaaacctaca aaaaaattat ttaaaggatt
    10141 ctttttaggt tttataaaag aattatgcca taaatatacc catataaatc ttataacaaa
    10201 taaaataagt acaattaaag tagaaataaa agtcaattcc aatgccatat tttcattttt
    10261 actactaagt cctgtatata tacttggtaa caaaaaacca agcagtgtaa agacaaatcc
    10321 attcaataca tactccaaaa cataccaagt attgtctgat attatcctta atttagtagt
    10381 tgtattttgt aaatgctctt tttcaattcc atgagctatc cctgccatta caacagctag
    10441 gattccagat actcctattt cttctgctac aaaatataca aaaagtggag tcattatttg
    10501 tataactatt accattggaa tttcttccaa attccacttg tgtaaactaa gtcttatttt
    10561 tataattatg tatcctaaaa tacttcctac tattattcct ccaaaagctg taatcataaa
    10621 ttgaatccct gcctcttcta ttgaaaaaac tcctgtaact gtggcaagta ctgcaacctt
    10681 aaatgctacg actccagcag catcatttaa taaagattca ccttcaagta tactcatcat
    10741 atttttagga aaatttaatc cttgtgtaat tgattttact gctactaaat cagttggaga
    10801 tattactgct gccaaagcaa atgaaacaga taatggcatc ccaggaataa gaaaatgtat
    10861 aaagattcca cctgcaaaca cggttattaa aactaaacca aatgcaagaa gcaaaattgg
    10921 ttttctaagc tctaatagct cttttctcga tacattttgt ccttcactga atagtaatgg
    10981 agctatgata catattacaa atatttctgg attaaatgaa aatgagaatt taaatggcaa
    11041 aatagacaat ataatcccta gtacaatttg atatattgca agaggaatat tactccactt
    11101 tttgctaaat acagttgaaa tcgttgtaca aaccaataat cccaacaatg ttactaaaat
    11161 tgacataact acctctcttt tcaataataa tattatagat taaacttata tatcaactaa
    11221 cttaatatta acagcatgaa atcccatctt aatcaaaaaa attttcagtt tattctatta
    11281 ttcttattat atacatcaaa tttaattttt gaaatatcta tactagatga catgcaacaa
    11341 aatgatttct tgatatttct tttaaaactg gaatctcttt tttgcatatt tccttacaat
    11401 aagggcatct tgtatgaaac ttacatccac ttggtggatt tgttggagat ggtatgtctc
    11461 cttttaatat aattctattt ttcttaattg tagggtcttg tattggtact gcgctcataa
    11521 gcgcttttgt atatggatgt tgagaatgta agtaaagttc tcctttagtt gcaatttcta
    11581 ttatagaacc tagatacata acacaaactc tatgtgcaat atgatttact acactcaaat
    11641 catgagatat aaataaatat gaaagtttat atttatcctg taaatccata agtaaattta
    11701 taatttgaga ttgaatagaa acatctagtg cagaaacagg ttcatcacaa actataaatt
    11761 ctggatttaa tgctaatgct cttgctatac ctattctctg tctttgacct ccagaaaact
    11821 cacctggttt tctatttaaa tggtacttag aaagaccaca actttctaca acatttaata
    11881 tattatcttt tatttcattc tttggcacta aattatgttc tataactgcc tcggatatta
    11941 tttgttccac atttaatctt ggatttaatg aactatatgg gtcttgaaat atcatttgca
    12001 ttttgggtct taactttcta agttcttcct tctctaactt atatatatct acaccattaa
    12061 attcaacttt accttcagtt ttttcaatta atctaagaat ggttcttcct gcagttgatt
    12121 ttccacatcc cgattctcca actatagcca aagtttctcc tttttttaaa tcaaaagaaa
    12181 ttccatctac tgcctttaca catttaattt ccttatcaaa taatccagat ttaacttcaa
    12241 agtacttttt aagaccttct acttttaata aactctcttc ttttttcaat tatatctcct
    12301 cctttttata taaccaacat gcaatactat gaccactatt caattctatt aaaggaggta
    12361 tctgagttct acatttatca catacttttt cacatctatc actaaaataa catgaatctg
    12421 gcattccaat tggatttggt acttgtcctg gaatcgaata caatctttta tctttgtttt
    12481 ttccaagagc aggctttgat tttagaagtc caatagtata aggatgtttt ggatttttaa
    12541 ataattcaac aacctctgcc acttctataa ttttaccagc atacatcact aatactttgt
    12601 cacacatttc tgcaactact cccaaatcat gtgtaatcat cattatagat gtgtttaatt
    12661 tttcttttat atttttcatt atatctaaaa tctgagcttg aatagtaaca tctaaagctg
    12721 ttgttggttc atcagctata agtaattttg gattacatga taaagccata gctatcatta
    12781 ttcgttgtct cataccacct gataattcat gtggatatga attatatatt tcttcagctc
    12841 ttggtatttc taccagtttt atcatatcga ttaccttttt cttagcttct tcctttgata
    12901 aatcttgatg tatcataata ccttcaatga tttgacttcc aacagtaaac gctgggttta
    12961 aagatgtcat tggttcttga aaaatcattg atatctcatt ccctcttatt cccataagtt
    13021 catcttcatt catctttaaa atgtctttgc ctcgaaagat tatttctcca ccttctattt
    13081 ttgatgttgg aagtaacttc atcaaagaca tggctgttac agacttacca catcctgatt
    13141 ctccaactat tccaatagtt tcaccttcat ttatattaaa acttacttca tttacactct
    13201 ttacaatccc tttatctgta tgaaaataaa cttttaaatc tttaacctca attagtgctt
    13261 tactcattat tttctcctct cagcaaaatt acttaagata acatacacct tttgattgta
    13321 ttttataaaa atttaaatta caacattttc ttacatttta ttattttttt ctattaatta
    13381 taataatata atagttaatt tctatatata ttgatttaat aatgattact attatacaat
    13441 aaaaaatatg tgttaaatat tattttatgg aggttttata agaatatgaa atttaaaaaa
    13501 ttggcatcat taatcttagt ttcatcatta atgcttacat ttacagcctg tgcttccaat
    13561 gataaagaca agtctagtgg aagcaaatct ggtggaactg ttgtaatacc tatggcaagt
    13621 gacccagata taatcaatgg agcttttgca aacgttaaag aagactctct tgcatcaaat
    13681 atagtttatg ctcctcttta tacttatgaa aaaggaaatt tagtaaatta tttagcagaa
    13741 aaagtagatt ttaaagatag taaggaatta actataaaat taaaatccaa tttaaaatgg
    13801 catgatggaa agccaataac tgctgaagat gttttattta catttaatac agttttagac
    13861 gaaaaacaaa attcaccatc aagacaatac ttattggtgg gtgagaaacc agttaaagta
    13921 gaaaaaattg atgatttaac agttaagatt actttaccaa ctgcaagtga atctttctta
    13981 tatggtatat ctaaaatttc tccaatacca aaacatgtgt ttgaaggaga atcaaatata
    14041 gctaagtcag aaaaaaataa taatccagtt ggttctggtg cattcaagtt taaggaatgg
    14101 aaaaaaggtg aaagcatagt atttgaaaag aatgcagatt attttggtgg agaacctaag
    14161 gcagattcta tagcgctaaa aataattcct aatgaagcat ctcaagaagc agctttaaat
    14221 aatggcgaaa tttcacttat gaagacatct gctgaaggat atgaaaaggc aaaatcaaac
    14281 tcaaacttac aaacttatac ttatagtgaa gaaagattaa actacattgt atttaaccaa
    14341 aatatatcaa acatggctaa caaagaagta agacaagcct tatcatatgc cttaaataga
    14401 aatgaaatga tagaatcagc atatggaaaa gaaggttctg tacctgctaa atctatatta
    14461 gttccagaag cagacttcta tacagaagaa ggtgttgaag gatatgacca agatacaaat
    14521 aaggctaaag acttattgga taaaagtggt gttaaaattg ataaattaaa aataggttat
    14581 aacacaggta gatttgggca taaaaactat gccttagtag ctcaacaaga gttgaaaaaa
    14641 attggtatag aagctgaaat agttccttat gaaagtaagg cattcttcaa tatactattt
    14701 agtaatagca ctgaatgtga tatgtatgta aatggttatg cttggggatt agaaccaaac
    14761 ccatatagag gtatgtttga aactggtcaa tattgcaacc aaactaaata ttctaatgct
    14821 gaaatagatg ctttatggga aaaaggattt actgagttaa acaaggaaaa acgtgaagaa
    14881 atatataagc aaatacaaca ggatatatct aaggatgcgc ctatttacac tatagattat
    14941 gaacaaaatt taatggcagc tcaaaaaaat ctaaaaggaa taaaagatgc taaaccatct
    15001 cctgcaatat tatttgaaga ttggtctaaa ctgtatgtag aataattgat gtaaaatttt
    15061 atattattaa ttagaaaagg agatgtctaa aaataatatt gttttattat tttaaaacga
    15121 gacatctctt ttaattagga gaatttactt atgttaaaat taatattgaa tagagtaaaa
    15181 gttttaatac ctatgttaat cttaatatct atattatcat ttggactttt agaattagct
    15241 cctggtgacc cagcagatgc atatataaat cctttaatgt cttcacagga tattgaaaat
    15301 ataagggtta atatggggct tgataaacca gtatatataa gatatttaaa ctggttgaaa
    15361 aacactttaa gtggaaactt aggtatttct tatataaacc atatgcccgt tacagaacaa
    15421 attatggaaa aaatgggaaa tacatttatt cttatgggta cttctttgat attttcaata
    15481 ttggtagcta tacctcttgg aatattttta gctgtaaata aaaattcaat aactagtaaa
    15541 gtatcatctg tttttaatta tataggtgtt tctatacctt ctttttggat aggtatgata
    15601 ctcatttcaa ttttttcagt taaacttaac attttcccat caggaggtat gcatactatt
    15661 ggaaatgata gtattggaga tttagtaaaa catttagttt tgcctgtaat aactttaggt
    15721 ctatataata ctgctatttt tacaaattat gtagaagcta gtgtaaatga acaattaaaa
    15781 aaacaatatg ttattacagc aagagcaaaa ggattatcag aaaaagtcat actatttaaa
    15841 catgtcttga aaaattcact gacatcattg gttacaatcc taggcatgag tatacaaaaa
    15901 ttagtcactg gtgcatttgt tacagaagta gttttctctt ggccaggtat gggaagatta
    15961 atgattgatt caattttttc aagagattat actgtaatta tggcaataac tatgttatca
    16021 gcactatttt taattttagg taatttagtt gctgatatac tatacttatt aattgaccct
    16081 aaaataaaat ctagcaaagg aggattctag ttgtgtttac aagtatctta aaaaaattaa
    16141 aaaaagataa atcctttgct tttgcatgta ttactcttag cataataatc atattaatta
    16201 taacttcttt tatattaaat atagactcta atgcaattga tactacttct aaacttcaag
    16261 aacctagctt aaagcatatc tttggtacag acgaacttgg tagagattac ttctctagag
    16321 ctctttatgg tggaaggatt tcacttagtg ttggtatttt atcaatgctt atttctgtag
    16381 tatttggtac tgctgtaggt gttattagtg gatatattgg aggtaagcta gaccaattct
    16441 tgatgagatt agtggatatg cttatgagta taccaagttt cttagttttg attgtattaa
    16501 atacttatct aacacctaaa gtttcctcta ttatactaat tattggattc ttaagttgga
    16561 tggaagtttc aagaattgta cgtggcgaaa cattaaaaat aaaggaaaat gaatactgtc
    16621 tagctgctaa agctactggt atcaaaacta gaaatatact attaagacat atagttttaa
    16681 acttaaaaga gactattgta gttgctggtt cgttaaatat tgctaatgct atcttaactg
    16741 aatctgctct tagtttttta ggtcttggaa tccaattgcc tcttgcatca tggggtaata
    16801 tgcttcaaga tgctcaaaga catatttttg acaagttata tttagctgta tttccaggat
    16861 tacttatatt tttaacagtc atgagtttga ctataataag caaaaaattt tctagtaata
    16921 cttaacaaat tttatataga aaataaaaac agtgattatc taaagatata cactgttttt
    16981 atttttcgtt taaaaaaata catattttgt atattataac tttaaatact actctaccat
    17041 gttatgtaaa gcctattatt gctctcaaac atatagatga aaaactaata gtttattata
    17101 ataaaaattg atttatttat ttgttatttt aataacattt ttaagagttc tttttactaa
    17161 agaaatctat aataaattta aatacatgtt ggtctacatg gctataacgt tcttttttag
    17221 gtctacatag tataactttc catgtaatag gatgattaaa aggcttttct ataattttgc
    17281 tattttcaaa aaaatcatga actggtgatg gtagaattgt tataaaatca gaatttgtgg
    17341 ttgatagcaa caaaaaatcc catgaaccag acattatata tctttttaac ttaacatttt
    17401 catcagtaaa tttttgcatt agcttatgat gtatcataaa agtaggatta aatattgcaa
    17461 gtaactgctc attcaaatcg ttccaatcta tcttatcctt cttagcaagt ggatgattta
    17521 tatttaaaaa tgctgtaagt tcatcttctt gaagcacatg ttcagttact acacttttat
    17581 caattttatg tggatgtaac aatactgcat aatctaattc ctgtaagata agcattctat
    17641 ttaagtcata tgcacccttc tctactatat caaattctat atctggatta tttgcaacta
    17701 actgtgcaac tacatctgaa aatgctattc caagtataag tggaggtatt cctattctaa
    17761 cttttccttt aaattgaact gaatcttctc ttaaatcttc catcatattt ttgtattcat
    17821 ttatgatatg ttctgcattt acataaaatc tttctcctgc tggtgttaac ccatttaacc
    17881 tacctttata cctttcaaat aaatatacat cttcactttc ttcaaaattt tttataattt
    17941 gacttaatgc tggttgagat atgtgaagtg tcttagatgc tattgataaa ttaaaaccag
    18001 atttcactat ttcaacaaaa tatttcaact gttttatatc cattttaaac ccccttcccc
    18061 aaaagtataa tttagattat attttttctt ctaatgatat tttataggaa aatcaacata
    18121 atttcattaa tattttaaca aaatattttt ctaaatctac tataaatttt tatcctataa
    18181 atttttctta tacactatat aaaaaattag acttagacaa aacgcttttt tcgccgtaat
    18241 ctataattag aaacaggaaa acctaaagca ttaggaataa aagtaattga aatacttaaa
    18301 aacaagcttg tattaaaaaa gtactttatt atagtgttcc ctgatttctt tattcagaaa
    18361 atttttaatt atcattcaag aaaggtaact attagatatg aaagatgtag taatcgtatc
    18421 agcagtcaga acacctatag gaagttttgg aggtgtattt aaaaatactt cagctgttca
    18481 acttggaact atcgctgtta aagaagcgat atcacgtgta ggacttaatt tatctgaaat
    18541 agatgaagta ataattggaa atgttcttca aacagggctt ggacagaatg ttgctagaca
    18601 aattgctata aatgcaggta taccaaattc tgttccaagc tacacagtaa ataaattatg
    18661 tggttcaggg cttaaaagtg tccagctagc tgcccaatca atcacatctg gtgaaaatga
    18721 tgtggtaatt gcaggtggta ctgaaaatat gagtcaagct ccttatatcg ttccaactgc
    18781 tcgctttggt agtaaaatgg gtgacataac catggtagat agtatgctaa cagatggcct
    18841 tattgatgct ttcaatcagt atcatatggg aataactgca gaaaatattg caactaaatt
    18901 tgaatttact agagaaatgc aagataaatt ggcattagaa agtcaaaata aggctgagaa
    18961 tgctataaaa aacaaccgct ttaaagaaga aatcgttcca gtagatgttt taatacgtcg
    19021 aggaaaaata gaaactattg ataaagatga atatcctaaa ttaggtatga catttgaagg
    19081 tttagctaaa cttaaacctg cattcaaaaa agatggcact gtaacagctg gaaatgcctc
    19141 aggtattaat gatggtgcag ctatgttaat actaatgagc caacaaaaag cagacgaact
    19201 aggtattaga ccacttgcta aaataaaatc ctatgcttca gctggtgttg aacctgaggt
    19261 catgggtact ggtccaatcc ctgcaactag aaaagcactg aaaaaagctg gacttagcat
    19321 caatgatata gacttaatag aagcaaatga agcgtttgct gcccaagcat tagctgttaa
    19381 aaatgaactt caaatagatt catcaaagtt aaatgttaat ggtggtgcaa tagcattagg
    19441 acatccaata ggagcaagtg gagctagaat acttgttacc ttaatttatg aaatgcaaaa
    19501 acgtaaagtt gaaactggac ttgcaacact ttgtattggt ggtggtcaag gaatatcaat
    19561 ggtggtttca cgataggagg aaatatgaat aaaatagtta gcattgatga agctctatct
    19621 catgtaaaag atggagatac aataatggtt ggtggattca tggccaatgg ttcaccagaa
    19681 aatttaattg attatttatg tagtaaaaat ataaaagatt tgacactaat ttgcaatgat
    19741 actggcttta ttgacaaagg agttggcaaa atggttgtaa ataagcaatt taaaaagata
    19801 attgcttctc atataggatt aaataaagaa actggaagac aaatgaacaa caatgaaaca
    19861 gatgttgagt tagttcctca gggaactctt gctgaacaaa tacgtgcagc tggttatggt
    19921 ctagggggta tactcacacc gactggtatt ggtactcttg ttgaggaggg aaagcaaaaa
    19981 attgttgtcg atagcaaaga ataccttctt gaaaaaccaa tttatgcaga tgttgctctt
    20041 ctatttgcat caaaggtcga taaagcaggt aatctagttt ataaaggctc tatgaacaat
    20101 tttaataatt taatggcatc tgctgccaaa attacaatag ttgaagcaga tgaaatcgtt
    20161 gaaattggtg atattgaccc aaatgaagtt aatacaccag gtatttttgt gaattacatc
    20221 gttgaaggag gtaatttata atggataaat tagaaatgca agaatatatt gcaaatagag
    20281 tatctaaaga attaaaagac ggagccgttg taaaccttgg aataggtcta ccaaccaaag
    20341 tagcaaatta tattccggat aatgtaaacg ttatcttaca atctgaaaat ggctttttag
    20401 gtttaggttc agccgaagat ggaaattcaa gtgatgaaac tattgtaaat gcaggtggtc
    20461 aaccagttac tatacttcct ggaggatgtt tctttgatag tgctacttct tttggaataa
    20521 tcagaggagg tcatgttgat ataactgttc ttggcgcact tcaggttgac aaatatggca
    20581 atatagcaaa ctatatgatt ccaggtaaga tggttccagg tatgggtgga gctatggacc
    20641 tagtaactgg agctaaaaaa gttattgtag caatggaaca tacttcaaaa ggttctgcaa
    20701 aaatattaaa taattgtact cttccactta ctgcaacaaa tgctgtagat ttgatagtta
    20761 ctgaaatggg agttatggaa gtaacatcag atggaatttt acttaaagaa ataaatccag
    20821 ctttcacatt agatgatgtt atttctgcta ctgaagctcc tttaatattg tcagattcat
    20881 taaatggaaa aatatctgtt gtttaaaata attaaaacta gaaaataaaa atctcttaga
    20941 tgtattacat ataaatttgt attgcttaaa atattaatat aaaaataaaa taaaattgga
    21001 ggaaatgaaa atggttaaag ataaagttgt attcgtaaca ggagctgcaa gtggaatagg
    21061 taaacaaata gctgaatcgt tcttaaaaaa tggtgctaaa gtaatgttct ctgatataaa
    21121 tcaagaagct ttaaataata ccataacaga gttacaaaaa aaaggttatg attgcatgag
    21181 tgtaaagtgt gatgtaacta aggaagaaga aattaaccac gctatagaca aaactgttga
    21241 aaagtatggc agattagata tattaataaa caatgctgga cttcaacatg tttctatgat
    21301 agaagatttc ccaactgata aatttgaatt tatgataaaa ataatgctga cagcaccttt
    21361 tatagctact aaaaaagcat ttcctataat gaaaaaacaa ggctttggtc gtataataaa
    21421 tatggcctca atcaatggtg taataggatt tgctggaaag gctgcttata actcagcaaa
    21481 acatggactt attggactaa caaaagttgc tgctcttgaa gctgccgatt ctggtataac
    21541 agttaatgct ttatgccctg gatatgtaga tactccactt gtcagaggtc agttcaatga
    21601 cctttcaaaa actcgtaata taccattgga aaatgtctta gaggaagttt tatacccact
    21661 tgtaccacaa aaacgcctat tagatgttca agaaattgcc gactatgcta tgttcttagc
    21721 aagtgataat gctaagggta ttacaggaca agcttgctta ctagatggag gatatactgc
    21781 acaatagtta ttatcacaat agttattata tttagggctt gaagaaagta ttcttcaggt
    21841 ccttctacta aggagggata tttatgagta ttatcgcacc aattggtata attattggta
    21901 tcatagctat tatatatttt tcagttaaag aaattcatat aactatagct gctccaatag
    21961 caactttaat agttgttatt ttaaataaaa tggatgttgt aacatcaatg ctaggtgctg
    22021 acaaaaacaa ttatatgggt gcacttggaa actatataat gagttatttt gcaatattct
    22081 tattaggctc aatacttgct aaatttatgg aagaaagtgg agctactgta tcaatagctg
    22141 attttatttt aaataaattt ggctctaatc atccttatag agttttagtt gctatattta
    22201 tagtaagttt tatattaacg tatggtggta taagcttatt tgtagttatg tttgcagtca
    22261 ttccacttgc aagaactcta tttaaaaaac ttgatatttc ttggaacctt attcagatac
    22321 cactttggct tggtattgca acaattacta tgactataat tcctggaaca ccagccattc
    22381 aaaatgttat acctattcaa tatctaaata cgtctcttac tgcagctact ataccaagta
    22441 ttgtaggtag tataggttgt gctacgtttg gacttgtcta tatgaaatat gctctaaaca
    22501 aaagtattag aaaaggtgaa acttatgcaa cttacacttc agaattagaa gaagaatctt
    22561 tagatagaga attaccagga ttttttgcaa gtatttttcc tctattagca ctcgtaatta
    22621 tagctataac tggaagtact tttggttcag aatttatgaa aaaaaatgta atttacatag
    22681 ctttaatagt tgcaattctt ttatctgctt ttttattcca taaatttcta tcatctaaga
    22741 tacagacatt gagcataggt gctagtggtt ctataggtcc tatatttgct acatcttctg
    22801 cagttgcatt tggagcagta ataatggctg cacctggttt tgatgtattt agcaaactta
    22861 taatgtcaat accaggtagt ccacttataa gtcttactgt tttgacttca acaatgtcag
    22921 caataacagg gtcctcttct ggtgcattag gaatagtaat gccaaacttt gcagattatt
    22981 atttaagtac tggtctaaat ccagaattaa ttcaccgtgt ttctacaata gcttcaaata
    23041 tactaactat agttccacaa agtggtgttt ttcttacatt cttaagctta tctaagttaa
    23101 cacataaaac tggatttaaa gaaactttca ttgtagttgc agttggttca ctaatagcag
    23161 aaattattgt aattacatta ggattactaa tgtattaata taaaacaaat taaaattcat
    23221 aatatgaaag gtggtgtctc aaagtgaact ttttacttaa tgagacactc tttttatatg
    23281 aaataacata tgcctatcat ttaaacaata aaaaagaacc ttatctctat tttgagacag
    23341 acccttttta tttcttaaag atttaaataa ttataatttg ttgctaatac gaaagcatct
    23401 actgaataaa tttaaccaaa taaaaaaaaa tttatcataa ctataaattt acgttatgga
    23461 attattataa aaatattatt ttctctaact aagtaattcc atactataca ggcttttaat
    23521 acaaattgtc aaacacactg aaatatacct atttattcca tatatatctt ttttacatat
    23581 ctttacagta aaaaaagtct taatcttatg ttagtataga ttcacgggta accccctaca
    23641 ctaaaggtta caaatcagta acatttttag aatttttaga ttaagaggtg tttaatgatg
    23701 agaagaaata taccaacaaa attaaaaact atattagctt taggagtgtt aactttagca
    23761 acagcttcaa gtgctgttac tgcaagtgct tcatcacttg aaaataatgt aaatataagt
    23821 aacaaaagtt tagtatatag taatactaaa tacaagtttt ctgcaaaacc aaattgttct
    23881 gtaaaaccag aacttaagcc tgataaagat aactcttgta aggataagaa tcataatgac
    23941 aagaattgca acaacactaa taaacctgag gacaacaata attcagactc tactaataag
    24001 cctgataaca ataaacctga gtctaataaa cctgaagaca acaataattc aggctctact
    24061 aataaacctg ataacaataa acctgagtct aataaacctg aagacaacaa taattcaggc
    24121 tctactgata aacctgataa caataaacct gatgataata acaactcagg ctctacaagt
    24181 gaaagttttt cagcttacca aaaagaagtt gtcgacttag taaatataga aagagctaaa
    24241 gctggattaa atcctcttac tcttgattct tctatatcaa atgttgctac aaaaaaatct
    24301 caagatatga ttgatgacaa ctatttttca cacaattctc caacttatgg ttctccattt
    24361 gacatgttga aaaaatttgg aataagctat aagacagcag gtgaaaatat agctatgggt
    24421 caaaaaactc ctaaagaagt tgtaaacgca tggatgaatt ctgaaggtca cagaaaaaat
    24481 ataatgaatc caaatttcag taaaataggt gttggagtag cacaaaaaag tggtggttca
    24541 atttattgga cacaaatctt tgtaggataa aatactcttt ttccatacat atcaagagag
    24601 tatctctaag tgataaaaaa cacaaatgag atactctttt gtatctattt taaaattatc
    24661 aaatccaaat atacatacta taaatattat ttgttctctt aattttagtg tgtaaaacaa
    24721 tatataaaaa gtattggcaa gatgaaaatg gaaaacttaa aaaagatatt taataggtaa
    24781 aaacaggatc ttaatatctt cataaaaaaa agctgtctca aaatagagat aaggcctttt
    24841 tcattgttga aatgattaaa atatatttga tttcatacaa aaagagtgcc tcatgaacta
    24901 aaaagctcac tttgagacac tctcttttat caattctata taagcattat aatactttaa
    24961 tattattcag ctaatttttt gtatccttca tatctttctt tagcatcagc ttcagcttta
    25021 gcaaataatc catcagcttc ctctgggaat tgtttagcta tagcagaata tcttacttgt
    25081 gcaagtatga aatctttgaa gcttgcagtt ggttcttttg aatctaaagt gaatgggttt
    25141 ttaccttcag cttttacttc tggattgaat ctgtataaat gccagtatcc gcaagcaaca
    25201 gcttgtgctt cattagctac agttcttccc ataccttctt ttaatccatg gtttatacat
    25261 ggagcataag ctattattag agatggccca tcatgttttt cagcttctaa aacggctttg
    25321 ataaattgat ttttatcagc acccatagca acttgagcta catatacgtt tccatatgtc
    25381 atagccatca ttcctaaatc tttctttcta gattttttac ctgaagcagc aaacttagcc
    25441 atagcagcag ctggagtagc tttagaagct tgacctcctg tatttgaata tacttctgta
    25501 tcaaatacaa gtacgtttac atcttcacca gatgcaagaa catggtctaa tccaccataa
    25561 ccgatatcat atgcccaacc gtctccacct agtatccatt gagatctctt aactagataa
    25621 tcttttctat cttttatagc ttttactaat tctttagctt tttcatctgt acaatcacaa
    25681 gctggttttt ctaataattc aacaacttta gcacttgcta ctttagaagc ttctccatca
    25741 tttctagaat ctaaccactc tgtaaatact gctttagcat cttcacagat atccatagaa
    25801 actaactctg tcatagcatc tactatttta tttcttattt gcttaacagc tgtgtacata
    25861 ccaaatccat attcagcatt atcctcgaat aaagaatttg cccaagatgg acctttacct
    25921 tcatggttac aagtataagg aattgatggt gcagaagctc cccatataga agaacatcca
    25981 gtagcattag ctatcatcat tctatctcca tataattgtg taactacttt aatgtacgca
    26041 gtttctccac atccagcaca tgctcctgaa aactccatta atggttgtct aaattgactt
    26101 cctttaacag tatttgcagg cataacatca acttttggag ctacttcatc aggatttact
    26161 gcaaatgccc aattatctaa ctctgtatca agttgagtat ctattggctt cataactaaa
    26221 gctttttctt tagctggaca tatgtcagca cagtttccac atcctgtaca gtcaagtgga
    26281 ctaacttgaa ttctatattt taatccttct aatcctttac ctaatgcttt tttagcttca
    26341 aatccttctg gagcattagc taattcttct tcagtaacta atactggtct tatacatgca
    26401 tgaggacata taaaagaaca ttggttacat tgaatacagt tatctattat ccattcagga
    26461 acatcaacag ctataccacg tttttcataa gctgcagtac cacaagggaa tgttccatct
    26521 tctataccat tgaatgtact tactggtaag ttgtttcctt cttgtgcagt cattggtctt
    26581 agtatatttt ttataaattc tggttcttta acttctcctt tatctgcatc aacagcattt
    26641 tcccaagaag ctggaacttc aactttaact aaagcattta ttcctgcatc aacagcagca
    26701 tagttcatat taactatttt ttcacctttt ttaccataag ctttaactat agaatctttt
    26761 aagtatttaa cagcatcttc ttctggtatt atttcagcta atttaaagaa tgcagattgc
    26821 attatcatgt ttattctgtt tccaagacct atttcttgtc ctagtttaac agcgttaact
    26881 gtatagaatt ttatatcatt tttagctata tattgtttca tatgagctgg taaatgttct
    26941 tcaagtcctg cttggtccca tatagtgtta agtacaaatg taccaccttt tttaagacct
    27001 tttaataaat catattgata aacatatgat tgtttatgac aggcaatata atcagcttca
    27061 tctattaaat aagtagctct tattggagta tcaccaaatc ttaagtgaga catagttata
    27121 ccaccagatt ttttagagtc ataatcaaag taagcttgag catatttttc agtatggtca
    27181 ccgattattt tgatagcttg tttattagct ccaacagtac cgtcagaacc taatccccag
    27241 aacttacatc ttatagttcc tttagaagct atttttattg gctcagatgg agttaaagaa
    27301 gtattagtta catcatcaac tatacctact gtaaatccat ttttaggttg ttctgaaact
    27361 aagttatcaa aaacagtttt tatatctgaa ggagtagtat cttttgaacc taatccgtat
    27421 cttccaccta ttatcatagg agcattttct tttccataga atacatcacg tacatctaag
    27481 tataatggtt caccagttga acctggctct ttagttctat caagtacaca tattctttca
    27541 acagtagatg gcatagcatc taagaaatgt ttcattgaga atggtctata taaatgaact
    27601 ttaactaaac catatttttc tcccttagca tttaagtaat ctatagtttc ttctattgtt
    27661 tctgttactg aacccatagc tattaatacg tatttagcat cttctgctcc atagtaatca
    27721 aataaactat gttttctacc tgttaaatta ctcatttttt ccatgtattt ttcaactata
    27781 cctactatat tttgatagta tttattagaa gcttctctag tttggaaata tatatctggg
    27841 ttttgagcag taccacgagc aactggatga tttggagata aagcattatc tctaaatgct
    27901 tgaactgctt caaagtttaa taaacttgca taatcttcat tttctagtaa ttcaactttt
    27961 tggatttcat gtgaagttct gaatccatca aagaaatgta taaatggtaa tctaccttct
    28021 attgcagcta aatgtgcaac aggtgctata tcagctactt cttgaactga accagaagct
    28081 aataatacac atccagtttg tctagcagcc ataacgtctt ggtgatcccc aaatattgat
    28141 aacgcttgag atgctaaagc acgagcactt acatggaata ctcctggtaa taactctcct
    28201 gcaactttat acatgttagg tatcattaat aataaacctt gagatgctgt aaaagtagaa
    28261 gttaaagctc ctccttgtaa agaaccgtgg aatgttcctg atgcacctgc ttctgactgc
    28321 atttcaacaa cattaactgt ttgtccaaat atattttttc ttccttgtga tgcccactca
    28381 tcaactactt cagccatagt tgaagatggt gtgattggat atatagctgc tacatctgta
    28441 aacgcatagg caacatgagc tgcagctgta tttccatcaa gtgttttcat aaacttagcc
    28501 ataatatgta tcctccttga tagctacaat tgtacttgtt tataacaagt ctattttttt
    28561 atatttacat ataatttaca caacaaaaat ataaacacac atatagtcgc gcaaatactc
    28621 tatcttctaa tataatacta cagattagat aaaattcctt tgaaaattgt aaattaatta
    28681 catatttaag tagatttttt ttaaaattaa atatgttaag tttttttcat aattttgtat
    28741 acaatatata ataaattaag ttagactttt caaacttttt tatctatttg tttatattag
    28801 tacaaaaagt aaaataatta tctttattat atgtaaattt ttatatatat aattttacca
    28861 tattacatca tatttttgta agtttttatt acatttttta taatacccct ttattttata
    28921 aattaatcta atcgattaaa tttatcctat agaaatttat tacatttaaa aatatgctag
    28981 caaataaaat atctactagc ataaagtcta tttataatat taatcaacta ttaattctac
    29041 taaatctcca tttttaacgc ctgctgcatt tccctcttcc atatcaacat gcatttctag
    29101 attaaagcta tcactagctc ttactaatac attttcaaat actaatgctc ttggtccaga
    29161 tgttttaact tttactattt gcttatcagt tacaccaaat ttagcagcat cttcattgct
    29221 catatgtata tgtctagaag caactataac tccttctttc atttcaactt ctccagcagg
    29281 tcctactaat ttaacacctg gagttccagc tatatcacca gattctttta ttggtgcttt
    29341 tactcctaat gggaaaccat ctgctaaaga tatttcaact tgagtatgag ctctagctgg
    29401 tcctagtact ctaactcctt ttaaagttcc ttttggtcct actaaatcca ctttttcttc
    29461 acaggcatat tgccctggtt gagataatgg tttaaattta gttaactcat gacctgctcc
    29521 aaataatacg tctatatcag cttgactcaa atgaacatgt ttattagata atgctattgg
    29581 taatttcatt gaaattccct ccttttaatt atttaaatta ttgcaataca attatacata
    29641 atattaccta caaaatcaaa ttatattgaa tcaatatata tctttaaatt tttatatatt
    29701 atatctttaa attcttgatt atctatataa gatacatcat ctgtattgtt taaatatata
    29761 ttgtgtaaaa gtttagtatt tatactctta aagaaaaaat ccataacaat ctgtccacct
    29821 ttaaactgtg aatcatatga tttactccct cccactgcaa tatacattcc tatccgtttc
    29881 ttacttctat caattgaagg tttatttaat acatatttac ttgcatatat agcttgagtt
    29941 ctatcaacaa cagtctttaa tttagctgat attgaatcaa aatgtacagg acttattact
    30001 atagttcctt ttgaatcatc aaacatttta tataatggct tcatatcatc attaaacttg
    30061 caataccctg ttttttcaca aaatccacat gctgtgcaat attcaatatc catattgtag
    30121 atattaaata ttttacaact taatccacac tcttctagca tagcttttac ttcatttgct
    30181 ataaaactgc aatttttatt aattctggga cttccattta ttattataat ctctggactt
    30241 ttaagtcctt ttttatcgtt tgaatccata atcaatctac ctatccttta acataactat
    30301 taaaatatca tcatcataat tatcttttga tgagaagttc tttaaatcca attttagatt
    30361 ttctactatt aactgttgat ttaatctaaa attttctttt agaaagtttt ctaatcggtt
    30421 tataccatac tcttcttttg atgaattttt tatctctaaa attccatcag tgtacataca
    30481 taccattgca taatcttcca ttgaaagagt attattttca taagtagcat cttccattat
    30541 tccaataggt atgccctttt tacaatttaa attattttct attgtgccat ctttctttac
    30601 aactacagga ctatagtgac ctgcattaga cacagtaatc atattttctt tagtatctat
    30661 aatacctatc aaacaagttg taaatactcc catcttgtca aattcatcat ataacatcct
    30721 atttaaattt gtcattattt ctcttggtgt attgtattga ttgcataata ctttaaaagc
    30781 accttttatc attgcaacaa cataatttga taccattcca tgtcccatta catcagcaac
    30841 aatataaact atatgttcgt catccacttt tgtagcataa taaaaatctc cacctactac
    30901 ccttgctggt ttatggtaaa aataaagttc tttctcatca ttacaatcca ttttaccttt
    30961 atccataata agctgttgtt gtttatttaa tatgttcaac tcattttcaa gaactttgtg
    31021 ttttacttcc ttttcattat gttcatataa ttgcatacca acagaaactt gtttggacaa
    31081 tatactaaga atatttaaat catcactagt atagtttttg ctatttgcac aaactataca
    31141 tcctatagtc tcatttttat cctgaagttt gtaatatata taactttcca aatttattcc
    31201 cttttttgag catggtttta aattatttag ataccccccc aatgactctt tctttaaaaa
    31261 catatcaatc ataggatata aatttgtttt ctttttttgc tcaacattat aacaactaac
    31321 tatagcatcc ttattatgat gactatttat aattattaaa gcttctttac tattagtaat
    31381 attacacgct tgtttactta aattttccaa aaatccatca atactcttat taaggtatag
    31441 ttttttagta gcttcattta tggcacttat tgagcctctt agtttatcaa ttaaaatttg
    31501 tacattatta tttttattag ttatttctat tgataaactt aagagtgatg caacagatga
    31561 tataaaatct atatcttgtt ctgttatata atcatcctct tttaaaaaac aagtcataaa
    31621 tccaacaact acgttattta ttataaaagg aaaaactatt ctcccaatat aaccttcagc
    31681 ttttgctaaa tctcgttcac cttctgctct agaatcttca aatacatttt ccacatatat
    31741 tatctttttt tcatttacag cctcatgtat atactctgga tatgtgtcaa aatcaatttt
    31801 tgcaccttta agactattta ttggaaaaat ttgaggtaca tattctaagg tttgcgaaca
    31861 tactaagtag gcatatttag aatcattttt ataaaataga ttcacacatg cctttgtagg
    31921 gtgaacaact tctaacattt tttctattat gtcatctttt atattaaaaa aatctgtaga
    31981 ttcagtcacc atagcggata tttccactaa attcttcatt ttataactgc cattagtcat
    32041 actcaatttc tccccctata tattaaacta tttattagta ttttaacata cattctttat
    32101 agtaaaaaca aaaacaacga caaaactagc aactaatatc cagttaaatc ctgtcaataa
    32161 tcctataaga agtaatgtaa ttaatgcatt tagacctgtt ctcccttttt catccataaa
    32221 agttatttta gagatgtcta tattattttt cacattattt atatgctctt ttacttgttc
    32281 ttccatattt cttttatata atatataaac tacaccaatt aaaaacactc ctatacctag
    32341 aaccatgttt aaattaaaag ctaccataag caatattgaa ccaaaagcta actttaaaag
    32401 cttaaaaaat acactatcta tctttagagt tatatttctg atttctttac attcatctct
    32461 taaagaatat ccacttgaat ctaagttatt aatctttgtt tttacaattt cagaataaaa
    32521 aagctttatt atcccattta acattttcat cactcctaaa tattttacat atatttgtaa
    32581 gttttacaat tataatattt tttatacttg gtaataataa aaaataacaa atattttatg
    32641 atttagtatt tattgtaaat aaattattga agctttatta gttaagtata gatttttaat
    32701 aaatattttt ataattagaa ggaagtggtt ttgtgcaaat agaacaactc gatttagaaa
    32761 cgagaaataa aatatactgc tatactaaaa aaattcttag aaaatatcaa aaaggcataa
    32821 catctggaaa attaacagca gataaatttg cagataatat attgtctcaa gattttatca
    32881 gtagtatact taatgaaaaa atagtcaatg agacaaactt taagatatct tatagaaact
    32941 atatagaaac tttaataaat attcaaaatg aaaatttatc taacttaaga aaaaaatcta
    33001 ctaaaactgc aaaatgtttc aatatctctc aaataaccca attaaaaaac ttactaagta
    33061 atactggtta taatttatta attccatata aatacttaac tgctagagat atagaaggaa
    33121 tcgttactct tattaatact gggtctattg aacttggaaa tgagagaatc tataattata
    33181 tatcaaaggc ataataattt aaacctatta taaaaaggca atttatttaa taaaaaatat
    33241 ttttaatatt aaataaattg cctttttaat tttggactaa atactgctat ccaagtgctt
    33301 tttctagttt agataaatgt tgtattggat aatattttag tagctcttta aattgttcta
    33361 ctgataaacc ttctgttgtt gtatatattc ttattttttc atctaagtca ctattaataa
    33421 atttgttttt taaatcctca aaatttacac tactcatttt acatcactcc ttatgtaaca
    33481 tattcatttg tattatttta tccaaataca taaaatttat tacataaaaa tatatctatt
    33541 taataatttt ataaaaaaaa gctatctcaa tttagaaatt actttctata tttgagatag
    33601 ctctagctaa actaatagcc aatagttata aataattatt tataactatc tgttgctttt
    33661 tccagccatt tgttgttcag ccatttcaac taatttttta gtcatgtatc cacctacata
    33721 accattttct cttgcagtaa ggtttccttt atcaacttgt tgataattac tcataccaag
    33781 ttcattagct atttctaatt tcatttggtt taaagcctct tttgctcctg gtactactgt
    33841 tctgttgttg ttattgttac ttgccatgtt gattaccttc cttctgttta atttattttg
    33901 tgttgctgat aatattatgt gattttaaac atttttaatt caggtaattt ttagcaatta
    33961 aaacctgcca aatatccagt agaaaaagct atttgcaaat tgaatccacc tgtatatgca
    34021 tctatatcta ttacttctcc agcaaaaaat aaaccttcta ctaattttga ttccattgta
    34081 cttgaattta tttcgtttac ttttacacca ccagaagtta ttatagcttc ttcaatgggt
    34141 ctgtatctct ttactgtaaa ctttaaattt tttaataaat ggactaagtt ttttctctgc
    34201 tctctagaaa tttggtgaac aaccatattt ggattaattt cacttaagtt tattattaca
    34261 ggtattagtt tttttggaag taaatcatct aatgcttttt caaatttttt atttgtatac
    34321 ttctaaaaat ctttttgaac tcttttatcc aatttttcct catctaatgc aggttttaaa
    34381 tctaacaata tagtgtaatt ttctttcctt gtatctttca ttctacaact tgcagacttg
    34441 attataggtc catctaaacc aaatttagta aattcaagtt ctccaaaatc actataaact
    34501 ttcttttgtt tgctattaaa cacccttatt tcaacatttc tcaatgataa tttttctaaa
    34561 tcttttgtaa aactttcttg tacttctata ccaattaaag atggttttgt atctataatt
    34621 gtgtgcccct gtgaaattgc aaatttatat ccatcaccag tagaaccagt aagtggataa
    34681 cttaatccac cagttgctac tacaactgaa tcacacttaa tttctttttt atcgtttaaa
    34741 attacttttt caattttatt atttttagat attatttttt ctactttcga atttaataat
    34801 atatttactt tcttactttt aagttgtctt tcaagagcat ttacaatatc aaatgcttta
    34861 tcactctctg gaaaaaccct ttttcctctt tctgttttag tctttactcc aagattatta
    34921 aacatactta ttacatcatc atttgtaaaa gtataaaaag cactataaag aaattttcca
    34981 tttgtaggta cattttctat taattcctct atttcacaag cgttagtaat attacatcta
    35041 ccttttcctg ttattgcaag tttttttcct aatttatgat ttttctcaat taatgttaca
    35101 tcatagcctt tctcacatgc agttgatgcg gctatcatcc ctgctggtcc accacctatt
    35161 attactacct tcttcaaata atcactcttt tctaccctta atttttttaa tttaaactat
    35221 tgactctata ccttaaaatc aatttaattt taaaagttta aataatgctg gagctcctgc
    35281 tattccataa aaaacaacta ctgtattctt aataaaattc ataaaaatta tactcatagt
    35341 agagtcactt atatttaaag tgactattaa cattgaaata aacaacttaa tgccaatata
    35401 taacattcct attgttacta tcccaaccaa aaacctacat attcttgaaa aaattacatt
    35461 tttactcccc ttatttttat tactaaaatt tatttttttg ttattattat ctgtattaaa
    35521 tttaacaaat ctatcctcaa ccatatatcc aaatacaaat cctactatta taccaatttt
    35581 ttcaaaatat tcagggctat ttagaaatat agccactatt ataaatggta taagtaaaac
    35641 tacaagtaaa atataatttt tattatcatc aatatagtca aatattttta caaatacaac
    35701 tgtaaaaaat attcctaata tccaacccgc tatcacatct attggccaat gaacagctaa
    35761 atacagccta gacaatccta ctcctaaaac cataactgca cctattaaat gaagatatct
    35821 ctttttaaat atagtcataa tactaatcca aaatgttgtt gcagtttgag tatgagcact
    35881 tggaaaagaa taaccaccag cagtagaaac tctcaatgat tcaagacctt ttattcctat
    35941 tggtctggga gcttttacaa actctttgat gcctaaattt acaacaaaat ttccaattat
    36001 agcaaacagt attttctgtc cacatttttt atttatacac cagtatataa ttgttgtaat
    36061 taatattaat aacggtgctt ctgtgcttat tgtaaagaca agaaatataa agttcaaaat
    36121 tggatttctt aaattttgga aaaataataa tatatttaac tgaatatcca tatagatgtc
    36181 tcctttacta aaattttata taattaacta aaaagcacta actcccttag aaattagtgc
    36241 ttttgattca catttaaatc tattctacat cctcaactat acctatataa ggtaaatttc
    36301 tatacttttc agcatagtct attccataac caacaataaa tttgtcttct ataacaaatc
    36361 caacatagtc tacaggtata ttagcttttc ttctctgagg tttgtcaagt agagtacata
    36421 gttttaaaga ttttggattt ctagttttta aagctgcaac tagattactt aatgttaaac
    36481 cagaatctat tatatcctct acaatcaaca cattctttcc ttcaatatct acatctaaat
    36541 cttttaatat tttaactgtt ccagaagact ctgttgagtt tccataactt gtaacactca
    36601 taaaatctat atttacatcc aaatctatac atcttattaa atctgaaaca aatacactag
    36661 ctcctttaag tatacctacc actagtaaat cttcgccttt aaagtcttct tctatctttt
    36721 ttcctaattc ataaactttt tcttttattt gttcttctgt caacattttt cctgtaactt
    36781 tgtacatttt gtatcctccc gctttccttc tattaactta tatattatag cataccaaaa
    36841 tatcaattaa aatctttttc atcattttta aacctaaatt aacagcttat ccatactttt
    36901 ttgcttttta cattaaaaat ttggaataac gattcctttg tattataatc tatatgtaca
    36961 tatattaatc agttattttt atcgattata taattttatt tttggaggta cttttatgag
    37021 cacaaatcat ggagctaatt tatatagttt atctagtaag tatggctttt caaaggaaga
    37081 atttatggat tttagctcaa atataaatcc ttttggtaca tcaagtttag ccaaacaata
    37141 cattgtaaac aatatagata tggtatctat gtatcctgac cctgattaca tagacttaaa
    37201 aacttctata tccaattact gcaaatgttc tatagataat atagtacttg gcagtggagc
    37261 tacagaacta atttcatcat ttatacatac aattaatcct aaacaagctc ttttactctc
    37321 tccagcctat tcagagtatg aaaaagagtt atctaaaatt aattgttcta tagaaaaata
    37381 ctttgcaaaa gaagaagata attttcatat aaatttagaa aatcttataa aaactatcaa
    37441 tgctaaagat tatgatttgg tagtaatctg taatcctagt aatccaactg gatttgcatt
    37501 tactaaagta gaagtgagag aaattttaaa aaatacagac tcatttttaa tgattgatga
    37561 gacttatgta gagtttactg atacagatac atactcttgt actcaattag ttgatgatta
    37621 ttctaattta ttcgttataa gaggtacatc aaaatttttt tcaacgcctg gaataaggct
    37681 tggatatggt cttatatcta acactaatgt caaaaatgaa ataaataaaa atctagattt
    37741 atggaatata aacataatag cttctaaaat gggtgaaatc atgtttagtg atttagattt
    37801 tatatcaaat actatttcct taatgaacac tgaaagagat tacctgctta aagagcttaa
    37861 gaatataaaa agcttagata tatacaatac taaaggtaat ttcatattgt gtaaaatcaa
    37921 gacaaaggaa ttgactgcta aatctcttcg agagcaactg cttccacaaa aaataataat
    37981 aagagattgt tgttcatttg aaggtctaga tgagtatttc tttagagtat gtatattaaa
    38041 acctaatgaa aataaattat taatatcatc tcttaaagca atttttaaat aaaaaaatca
    38101 ctttatttta taatttttta taccataaaa aatgagctat ctctatttga gataactcat
    38161 ttttgattat taaaaaacta agcactttgc tcttctttat ttcctttttt actcattcca
    38221 tcatttattt tatctactac tactgctatt gcattatctc ctgatacatt acatgctgta
    38281 ccaaaactgt cttgagttaa gtataaagct atcattaaac ttgcaagccc accatctgat
    38341 ggtattccaa ccattggtag gaaaggaagt gcactcatta tagccccacc tggtgctcct
    38401 ggtgctgcaa ccattgctat acctaacatt gcaatataag ggaataatac acctattcca
    38461 tgtggcatac cattcatcat taaaactgca gttgtaaatc ctgttattga tatcatacta
    38521 cctgataaat gtattgttgc acaaagaggt acaacaaatt ctcttatttg cttacttact
    38581 ccattttttt ctgcacaacc aacattaact ggtatagttg ctgctgaaga ttgagttcct
    38641 atagctgtta aatatccagg tacttgattt tttaacattc ttactggatt ttttcctgaa
    38701 aatacacctg ctgctgtgaa ttgacatgcc atatatacaa aatgtaaagg tattactact
    38761 aagtatactt tccagaatac ccctaatatt gtccatactt cccctgctat agttatattt
    38821 gcaaaagttc ctgctatgta taaaggtaat aaaggtataa tcactgttga caacgttttc
    38881 gttacgattc cttgaaattc ttggaagaaa ttaaataaag tctctccttt tccatgattt
    38941 cttaaagctg atattccaag tcccattaca aatgcaaata cgattgcagc tgttacatct
    39001 accataggct ctaatggaat tgtgaatatt ggagctaaca ttcctgcctc tgggtctcca
    39061 atttgacttg caacacttgc atcaataaaa tttgggaaga ttaatgtaga tactgcaaat
    39121 gataataatc ctgctattaa ggtagaacca tatgctattc ccgtagttat ccccaataac
    39181 tttcctgcac ctgttgctaa atcagctata cctgctgtta caaaacctat aattataaat
    39241 ggtataacaa attttaggaa tgctgagaat aaagtactaa ctgttactaa tatttgtact
    39301 attatttctg gtgcataact tccgattaaa ataccgacta tgataccgat gattagtttg
    39361 ggcactaaac ctattttttt cttcataata tttaccctcc ataacttttt taaattaagc
    39421 attcttgcac attgaatact tagttaaata ttggatatcc acttattatg ataatagagt
    39481 tttacctctc cgtcaacaat ttaaccattt tttgttaata aaaaaaagaa taacatatat
    39541 aaattgttat tcttcttcat cttttataga aaattctaca ttttcaatta tatttgaatg
    39601 tttatctttt tttgcgataa ctctatactt attaatttct tcattcacta tacctatact
    39661 ccaaattaaa actatagcat catctataaa accaaatgcc cctgcaatca tctctggaat
    39721 tatatcaacc ccagatacaa agtaggatat agtaaaaatt aatacagaaa ttacctttat
    39781 tttatcaact atattgattc ttttatctgt cataaaatca ggtagtttaa gtaaatcaaa
    39841 tacaaaaacc aaaccaaatt tagcattttt aaatctgacc aaaatttttt ttaaaatatc
    39901 taaaactata ttaatgatta tttttaaaaa ctccatattt atcacctctt ataattatag
    39961 gttattctac attataaccg atataattaa tttgatgaac atattagata taaattttat
    40021 caattagttt atatttaaat tataataatt caattcctgc actactacaa ttttgaatca
    40081 tatcctgtgg ccatactcca acttgtactt ctcctatatg agctttttgt aagaaataca
    40141 tacatattct tgactgacca attcctccac caattgtata cggaagttcg ccatttaaaa
    40201 gcatcttatg atagtcaaac tcttttctct cttcacatcc agcaagtttc aattgtctat
    40261 caagagattc ttcatcaact ctaattccca ttgaagataa ttctaatgct gaatctaaaa
    40321 caggattgta aaataatata tccccattca attcccaatc atcataatca gggcttcttc
    40381 catcatgttt ttctcctgat attaatgttt ttcctatttg agttataaat actgctttct
    40441 tctcttttac aattttatct tctctttcct ttggtgataa ttctggatac atatcttcta
    40501 actcttgtga tgttataaaa gttatttctt ctggtaatat ttcttttata ccttcataca
    40561 tactacatac aaaaatttca gtatctttaa atactccata caatcttttt acaacatctt
    40621 ttagagtttt ttcatttcta ctacttttat ctataaccaa ttcccaatcc cattggtcta
    40681 cataaagaga atgtatattg tctaattctt cattttttct tattgcattc atatctgtat
    40741 ataaaccact accaacttca aacccatatt ttttaagggc taatcttttc cattttgcaa
    40801 gtgattgaac aatttctgca tttttattca taaatggtat atcaaagctt acagcctttt
    40861 ctccatttaa attatcattt gcacctgttt ctggcaatac aaataacgga gaagaaactc
    40921 ttataagatt taattcatta cttagtctca tttcaaaaaa atcttttaat ttttttatag
    40981 ctatttgtgt atcaattacg ttcaaactac ttttataatc ctttggtatt attgtgctca
    41041 tatcattcac tccctatatt tatatatttt tccattaaaa aaacccttca tccctatata
    41101 aaagggacga aaggttgctt ttccgcggta ccaccctgat tagtttgaaa taaattcaaa
    41161 cccagctcac aatgtacaga tattactcga tacaccccaa tatgataacg gtttggttcc
    41221 gactaagcct actcttttaa aatttcggtt agcaactcca ggatgttctt cattatagac
    41281 ttcatattgg tctcacacca tcaccaactc gctttaatta cattctataa ctactcttcc
    41341 tttcaaagtc tttaagagtt taattcaata aaatttagct ctcttatgtt ttctatttat
    41401 tcataatagt atgataagtg attagttaaa atttgtcaag tttattattt ttttattttt
    41461 aaacacttta taaattttta cctatacttt ataaattttc aaatatagtc tttaatctgt
    41521 ccatacattc ttttaataaa gactgtggac aagctacatt tattctttca aatcctattc
    41581 cttcttttcc aaatatataa ccttcatcaa ataatacatt agctttttta aacattaaat
    41641 cctcaagttc tacttcattt aatccataag cagtaaaatc taaccatgct agatatgttc
    41701 cttctggata aacaagtttt acttttggta ggttttcttt taagtattca tcaataaatt
    41761 gtatattatt atctaagtaa tcatttaatt cattaagcca gtcttcactt tcattatatg
    41821 ctgctattgt agctacaata gcaaagggat ttggtgaagt tgcaactcca acagctgtaa
    41881 cctcttcttg atatttcttt tttagttcat cattattcac tattatatta gacaactgca
    41941 ttcctgccag attaaatgtt ttacttggag ctatacatgt aactatttta tccttgtact
    42001 ctgggcataa tgactgtaaa ggagtatgtt taaatccttt tctaattaaa tcagaatgta
    42061 tctcatcagc tattatccat aggtcatatt ttttacatat ttctacaacc ttttttaatt
    42121 catcttctct ccaaactctt ccaacagggt tgtgaggact acaaagtatc agtactttat
    42181 tgttgctaca cttagctttt tcttctaaat catcataatc catcctataa gtaccattct
    42241 catatattag aggattgttt acaacgtccc tattattgct ctttatctta gcttcaaatg
    42301 ggtaatacac tggtttttgg actattacac cttcattaga attagttaat attcttacta
    42361 aaatagcaac agcaggtaca acaccaggac taaaaataat atcttttcta tttatttccc
    42421 agttaaatct ccttttatac caatcacaaa ctgcattaaa gtatttatca ctatcatttg
    42481 aactgtatcc aaatatttta tgttcaactt ttttacgtaa tgcttctatt attggttctg
    42541 cacattcaaa atccatatca gcaatccaaa aaggtaaacc atctttttgt gcttttgttg
    42601 aacaattagt tctaaaatcc cattttacac aatctgttcc tactctatct attactctgt
    42661 caaaattata cttactcatt ttttccctcc taagaataaa atttttataa ttgttaagtc
    42721 tattactaga tgcactttgg tattatttta caattcttaa tattataata atatcacttt
    42781 tttgtccaat agatttaaaa tataattact tttccatcat attttttcaa tattccaaag
    42841 tcagtttcat tatatcaaaa taagattgct catattaatt attttctaat taacataagc
    42901 aatctttttc tataacttct ataattataa ttttaaatgt agaattatta gtttggatat
    42961 tatcccaatc tcttttcaac caatctacac catatatcta caccatattc taaagctttc
    43021 gtatcaaatg ttacatttgg attatgaaat cctggtgtag catcagctcc taatccaata
    43081 tatgtagttt tacattttag tttttgtgta taataatgga aatcttctcc accagaattt
    43141 ttaaatatac ctatagatgc atcagctccc aatacatctt ttatagtttc ttcagccaag
    43201 tttacaagtt cttcatcaaa ttctgctgct ggtactccat ctttggaaat tagtacagct
    43261 tctgcattta tagaacttac agcagttttt acagcatgta ttgctttttc ttttaattct
    43321 tctattatat cattactttc tgcccttata tctaaagcca taaatgcttc atctggtata
    43381 ttattataag tttctccctt aactgatata tttgttactt ttatagaatt tggtatagct
    43441 ggatttactc ttattgcatt tattgcattc actgctaaac agacagcatc tactgcattt
    43501 actcctaaat gtggtttaga accatgacaa gtgatacctt taatcgtaaa ttccattata
    43561 cagctagcac aatggtacat tgcaggtatc gcctttccca acctacaatc ttgtccaggt
    43621 cttaaatgca tccctaccat ttcttctaca tcatccaaca aaccagaatc aattactctt
    43681 aatgctccat ataatttttc ttcacctggt tgaaaaagta tttttaactt acctcttttt
    43741 actaaatttc tctcttttat taactttgca gctgttaaaa gcatagaagt atgaccatca
    43801 tgaccacaag catgtatcat tttcttttct ccatctatga taaattccaa tgcatccata
    43861 tctgctctta tagcaaatac tggtccttct tttttagaat ctatagttac tataatacca
    43921 gttcctgcaa ctcctttatt aatattttca aaccccattt tttcaagctc ttttaaaaca
    43981 aactctgatg tcttatattc ttcaaatcct ttttctggta tagtgtgtag ataatcatac
    44041 actttatgta catactcaat ataatctttg ttagtttcca taatctagct cctccttaaa
    44101 atttaaactt tccatttata ttaaattttt attataatta cctatactac gaaataattc
    44161 attataagca ttgcaataca accatttaaa gttgctataa caaacatatg tggataatat
    44221 ttagttttta actcagctgt tcctaaaagt ctccccataa attgtatctg cgctcctgaa
    44281 agcaataaca ttggcaatag aattgcaaca tgtgcttgac ttatttgacc tgctgtaaat
    44341 aaacctgcga ttactccaga tgctcctccc attgatataa atattgtcat tatagctgtt
    44401 gctgcaacac ctggaagtcc aaagatactc attacaggtg taaatattgt ccctattaca
    44461 tccaaaagac ctgttaaatt gaacacagaa attatagcaa aaccgaagat gacatttgga
    44521 gccattgaat ttgtacttat ttggaatcca tttctagctc ctccaataaa cgcatctatc
    44581 acatttcctt ttttaacttt tacttctttt tttgctacct cactcatgtt aagcttcccc
    44641 cttgtcaaat ttatttaaat ataatctaag taagttcgcc ccaacaaact tcataattaa
    44701 tattaaagca agtggtataa atattggtac atctcctata aatggaaata atgctgctcc
    44761 agaagcaaag aaattcgtaa ttgcagacgc acctgaaaat tgaaatgcac aaaatacagc
    44821 tttttgtttt tcatctatat acccatcatc tttaagttct ttagtcatag atgcagctgc
    44881 atctgtagac tgtaaactag ctatcaaagt tagtcctgca aatccaggta accctaataa
    44941 tggctttaat agtggactaa gaagcttttg agctgccttc attccatcta agtggtctat
    45001 aactctaact actccaagtg caaacataac tgatggtatt aatgtcaatg catatagcca
    45061 tccatctcga gggccagtac ctccatcacc tctaaagttt gcagctaatg tacctacacc
    45121 atcattaatt gttcccaatg ttccaaaaga acctaataca ttgttaaaat ccaatacttt
    45181 taatggtcct ggtgcatctt taaatattcc tgaaaaaaat aatgcgccca atattaatgc
    45241 tacataccca taccatttta cctcaacttt ttctgttgtt gattctaatt tactcatata
    45301 aattctccct cctgtttaaa tgaattttat tagtatactt gtttaataag caaaacttat
    45361 gccaatacct taatgataaa gcctttgtat ttattttttc attgtaaatt tattccagtg
    45421 attaagcagc ttataattac ttacttttca agtttaaaaa tataatattt ttttattaat
    45481 tatttaaaat atacattaca atataaaaag ctattttcct tatcttgcaa aaataatttc
    45541 aaaataggtt tttataggat aaaatcctaa aaaaacctat tatttaatca aatatataaa
    45601 tttataccac tatttgttgt ataatataac ttgccttata ctttaaatac tttaaaaata
    45661 aatactattt tgttaggaga aataaaatgg ataaaaagaa gttaatcctt ataacatatg
    45721 ataaattgaa tagtgaccac tacaaagaag aattaacaaa cttttttgga gacgaaataa
    45781 tcatagaaac acaaaatata cttgatggaa taaaagaaaa tttagaggga gatgtagtgc
    45841 tttctctatc acctttaact agtaattttt taataaaaca ttttaaggaa gatattgaaa
    45901 ttattcatgg aacgaaagca ctttcaaaac ttggatatga aaaaatgatg aaactgcctc
    45961 caggtacaaa atcgttactt atgacaacca ataaaacttc agcatttgag atggctactt
    46021 atctatataa aattggtata aatcatatag attttgtacc gacatatcca gattgtgatg
    46081 aaatatatga tttagataca gctataacac caggtcagat tagatttata ccaaaataca
    46141 taaaaaatat tgttgattta ggttggagaa aaatctcatt agatacatat atgtcattat
    46201 tagtagtatt aaaactaaaa aatgagaaat ttatagaaaa actatacaaa ttgtccaagg
    46261 agacactaag tcatgatttc ttaaatacat cattagataa tatatctaaa ttaaaaacta
    46321 tactttacat gaccattgat gaaataggtg atggtctaat atttttcaac acctttaaca
    46381 aggttacttt tgtaaataag tctttactta atatgttgga actagatgaa aaacttataa
    46441 aatcaccttc cttaatggaa tatatgccaa agagtttctt agataaaatt acaaagaact
    46501 taaatataga taatatgatt atatacatag acgaaataga taaaaaattc atactttcta
    46561 aaaaaccatt ttatctttat aaaaatatag agggttgctt aattacatta aaagatgtaa
    46621 acaatataga aatattagaa caaaaaataa gaagtgattc tgtcaaaaga ggttatgtag
    46681 ctaaatataa atttaataat attattggaa gtagttctat tataaaagat tgtattaaaa
    46741 aggcaaaaaa aatggctctt acagataatc ctatattaat aacaggtgaa acaggaacag
    46801 gtaaagaagc ctttactcag tcaatacaca atcattcaaa tagaaaaaat aaaccttttg
    46861 tagcaataaa ttgtgcttca ttaccaagtg aattacttga aagtgaacta tttggatatg
    46921 aagatggttc ttttactgga gcaaaaaaag gtggaaaaaa aggattattc gaattagctc
    46981 atactggcac tatattttta gatgagatag gagatatgcc acatgattta caggttaaac
    47041 ttttaagagt cttacaagaa aaagaaatta gaaaaattgg tggtacaagt attattccaa
    47101 ttgatgtgag aatattagct gccacaaata aggatttaga aaaattaatt atagaaaata
    47161 aatttaggat agatttattt tataggataa gtatgttcac tttagattta cctcctctta
    47221 gaaagagatt agaagatata cctcttcttt tagaatcatt tttaaaagaa cttccctata
    47281 aaaacataaa actcgataag agtcttttag aagctttaaa ttcatacact tggatgggga
    47341 atattagaga actgagaaat tgtgttgaat atatggctta catgggttcc aattatctta
    47401 caataaatga tttacctcaa aacatatctt caaaattaaa taataatcat atgtcaagta
    47461 atatgtccat attcaatgat ttaagccaat atgacaaaaa catatgcatt tctatcctaa
    47521 aatcattgca catgaaacca atggggagga caaagttaat gaaatttatg gaatataatg
    47581 tcacagaata cgaagtaaga aatatgctag agtatttgac acgcaatgga tacttaattt
    47641 ctagtaaagg aagaaaaggt tcatcagtaa ctgagaaagg cataaaaata atagaaaata
    47701 atataattta aacctatagt aattcatctt tactttatca aaatttatat ataattataa
    47761 ttttttattt ttctataaat tttttataaa ataataaaac ttatttatat taaaaacgaa
    47821 gctatctcaa catagggata agcttctttt taattgttaa aaagataaaa atatatttga
    47881 tttaatagaa aaagagtgcc tcataaacta aaaagttcat tttgagacac ttccttaata
    47941 ttaataaatt aattggctta aaattactga ttgataatta taaagtacct ctgttaaagg
    48001 agtaaattct gaaccgattc caaatcttaa ttctgtaaac gcctctaaat aatctgggtc
    48061 acatacatct tcttgtgtta aatcttgttt caccatttca gtagcaagat aaattgctac
    48121 tgatggtaga aaagcatcca ttggcatagg atatccacca agtctatttg acatgccaaa
    48181 agccttagcc ttttcactta tcatgtcgtt tattttatca taattttgag catctttttc
    48241 agatattttt agacccataa cactaggata tgtttgtatt ggtgatggat tgctttgctc
    48301 tgcaactata tactttaatt ctaaagcctt agtcaatata acttcatcca tatactcatt
    48361 tacaccaaat acatttatat cttttccata ttttttaact tgtttttcaa tatcttcatt
    48421 taaaaactgc ttaactttgt ttttgtcttc ttcagtattt atatttggag tattaacttg
    48481 tacaaatggc aatcctatat ttttgcaagt ctctttaatc atttctaatc ttttggctat
    48541 attaacatct ttcaaatcat ctgtagaggc ataatgaata aaagcttttg ctcccatttc
    48601 ttttgaacgt tcagctaata cttttcctct ttcttctgca ctaaccccta gattcacatc
    48661 aacaaattgg cttaattggt ttttatcatc tcccataggg gcagaaatag ttattatttc
    48721 tggacgcttt tcctttacct tttgtaaagc aggtaaaagc cctgcttggt cagttgaaac
    48781 tacaatagcc tgaacttctt tatcgtcagc caactttact atcttattaa tagcactatc
    48841 tatattagaa gtaaaattct ctggcaatac aacatgcttt atagtttgtt taactttagt
    48901 ttgaccatct ttgtctttat caattttatt ctcttcctca tattcttttg ccatctcttc
    48961 caccatattg tattgtactt tattttcaga taatggttga gttaccactg caactttaaa
    49021 atcatctata attttctctt tatctttctt gcctacaagt aaactacaac ctgtaagtcc
    49081 aataattaaa catatggata gcataaatgc tgttattttt ctaagcatta attaaaacct
    49141 cctaaatttg tacattctta tcactattac taattttatc atacttcaaa gaaaaattat
    49201 attataaaaa attatataca tgctattata atccaatcta aaaagtacta tgggtagatt
    49261 aggtttagat taaacctacc catagtacta aaaattaata tattataaaa ttaaattaat
    49321 tacaaattat tatgctactt gtttgttgct ttttataaag ttaccaacta ttccacccaa
    49381 tatagctggt attacccagt taaagcccaa acctgcaagt ggcaagcttt gtataaatgg
    49441 aacagctcct gtcattccat ttatagctga taataaacta atcactaatg taacatatgc
    49501 tgcaccttta aaagcattat cattctttat atgtttacca gccaactcca taacaactat
    49561 tgctaataaa acaggatata tagtttgtag gattggaact gatatggcta ttatagaatc
    49621 aacacctaaa tttgatataa gcatactagc tacacatata cctataacca gttgtttata
    49681 actcgcctta cttattcctt caaaataagt tgatattgat gctgttaaac ctgtagaagt
    49741 agtcagacag gcaagtgcca caattacacc taaaattacc tttcctactt gaccatataa
    49801 caatatacta gttatttcaa ctaataaaga tgcttgaggt atactagtat catataaagt
    49861 tgaaactgtt gcacctaaat aagtaagacc accatatact actgctagaa atacacaggc
    49921 tacaaaacca gctttaatag tcattcctat ttggtcttta tctgatgtat atcctttagc
    49981 tattatagac atcaacatta tagttgccat agatgctgca cctagagcgt ccattgtttg
    50041 ataaccttgt gatatacctt caccaaatag atttttatct atcatatgct caggactcat
    50101 aggtcctgct ggagaaatta taccctttac tattaaaaca aataatacta ataataacgc
    50161 tggagttaaa tacttaccta ttatgtctat aaccttagaa gacctaatag taaatgctaa
    50221 agttaaccca aagaagatta ttgaaaatac agctttagct actggaccat ggtctccaaa
    50281 tataggcata atacccattt catatgttgt tgcgcaagtt cttggtatta caagaagtgc
    50341 taaacatgct agagcagcta cactcattac tcttgctaac cctttaccag ctctcctaag
    50401 tacatcatcc atgcttccct tgcatcttgc tgttgctata ataacaagca ttgctatacc
    50461 agcatctgca acaacaaatc caataagagg aattaaccag tctttgccgg attccatccc
    50521 taaaaatgga ggaaacataa gatttcctgc accaaagaac atagaaaata aagcaaaacc
    50581 aactataaaa atatctctca tctgcttact cacactaaat tacccccttt gaaaatattt
    50641 tgaatattaa gataatctta ctttattttc agaaaaatgt caatctggta aaaattcaca
    50701 cattgttaac gttttcccaa tttattttat gaatattttt ttcattttat gataattccc
    50761 atcaatttcg ttaaatcaat tgcttgtgac acatcaaaaa ttgctcctct aatatcatct
    50821 ataccaatct caattccctc aatattatta gtagtaaaat ctatgccaga aagtttagtt
    50881 ccattaaagt ttgctttttt taaatttgta tactcaaata ctagattgtc accttttact
    50941 tcttgaaata cagaattttc aaaatttgaa tctaagatag aaactatctt aaatttagag
    51001 aatgaaaagt tagaatactt acctaaaaca tccttgaaca aaacgttttt aagtatacaa
    51061 tcatcaaatc taactcctat caatttacta tttttaaatt caactctgta tatacttcct
    51121 ccatcaaaaa atgtatttga taaattgcag ttttcaaata ccacatcaag taaatcaatc
    51181 ttttttaaat tacaattttc aaaagacaca tttctaaata tacaagattc aaagctaact
    51241 cttacagaat ctaaatcact tataacttca ttttctataa ttttattaaa tattttttca
    51301 tcattaaata tatcttcaag tatatcttca agattttcaa taatttctaa ttctcctgta
    51361 aatttaggtt tttgcacttt aataatttta gtcattttcc cctccactat aaattatatt
    51421 atttttgata ttattttttt taatatatta acttaatata catatttgat atattaaaaa
    51481 gtttttacga aatatccatg tattcagtac ttttataatt atatcacaaa ctcatttata
    51541 ataaacttcc attaatagta taaaacaagt tagaataatt gacattatac tcatacatat
    51601 tcaattattg gaaaaagtaa tttttttcaa taaataacct taatttttta taaaatcgac
    51661 aaaaaaacga ataattttat tatatttatt gtaaataata caatattacg atataataca
    51721 acagaaaaac aaatagaaaa tgttcatata atattagtaa tacggtctaa tagtttctac
    51781 aaactcacct taaatgggtt ttctatgaat agaatgtcaa ctctgaatat atgttctatt
    51841 ctatctatat gaatatatat ttttttgttt atatcttaaa gttttttgga ggtaaaaatg
    51901 gtaccaaaca ctaacaatgt acaaccaggt ggaaataatt catcattaag ctttttagac
    51961 aaaatgttta aatttagcga acgtggctct agccttaaaa cagaagtaat aggtggagtt
    52021 actacattct taacaatggc atacatagtt ttcgtaaatc cagcaatatt atctgaagct
    52081 ggaatggata aagccgccct tataacagtt accatactag ctacagccat tggtacactt
    52141 atatttgcga ttttaggaaa tgcaccattt gctctagctc ctggtatggg attaaatgca
    52201 tttttcacat actctttggt tataggtgca ggaatcccat ggcaaacagg tcttggggta
    52261 gtttttctat ctggatgtgt cttctttaca ctcgcagtaa caggtcttcg aaagacaatt
    52321 gcagacgcaa ttcctagaga attggcagta gcatcttcag caggtatagg tcttttcctt
    52381 gcttttgttg gtttaaaaaa tatgggtgtt ataatagcta atccagatac tatagtttca
    52441 cttgcagatt ttacaccaac agttttaata gctctttttg ctcttatctt aatggcaata
    52501 ctagaatata aaaaagttaa aggtggaata ttgataagta tagtagttgc aacaataata
    52561 tctgttatat ttggatttgt ggagttgcca acagcaataa tctcaacacc tcctagtata
    52621 gcaccagttg cttttaaatt agatattgta ggtgcattga aattctcatt aattggacct
    52681 atattctctt tcatgtttat agacatgttt gattcattag catttcttat tacttgttgt
    52741 aaacaaatgg gtcttgaaga tgagaatggt gaaataaaag atttaggaag aatgttatat
    52801 gcagatgttt cttctacttt aataggctca ttcttaggaa ctagtactgt tacaacattt
    52861 ggagaatctg cttctggtat tgcagcaggt gcaagaacag gacttgcttc aatagtaaca
    52921 gcagcattat tcttagctac acttatattt acaccattac ttggtatagt tcctacttac
    52981 gctgcagctc ctgcacttgt aatggttggt gtattcatgt ttgaaagcat aaaacagatt
    53041 gattttgctg atagcaaaat agctgtacct gcttttgtta cagttttatt gatgccttta
    53101 acttatagta taagtattgg tttatgcttt ggatttattt catatataat aatgcatgtg
    53161 gtagctaaag aaactgacaa aatcagtatt acactttgga ttataggttt acttgcagtt
    53221 gtaaacttag ttctaagtta atattttaaa tagttctagg tcaatatttt aaatttataa
    53281 atagcaaaat caatttatgt ataaattgat tttgctatta actttgtata gaaaatttat
    53341 tatcataata catagatata aaaatatata gaaaagaggt tgtacttatg tcacaattac
    53401 ttataaaaaa tgcatatcta attactatga atgcagatag agaggtatat gaaactggaa
    53461 gtatacttat tgaaaataat attataaaaa atgttggtaa gtttgatatt aatattgtag
    53521 ataaagatgc agagatatat gatgctaaag gaaaaatact aatgccaggg ttagtcaata
    53581 cacacgttca cttatcccaa caattaggac gtggtcttgc agatgatgtt gtacttttaa
    53641 cttggcttag agagagaatc tggccatacg aaagtagctt caactatgac gattcattga
    53701 tttcatctac tgcatgttgt gttgaattga taaaatctgg ggtcactaca tttttagaat
    53761 ctggtggtca atatgtagat gctatggttg aagctgttga taaaactgga cttagagcct
    53821 gtttagctaa atcagttatg gatacaggag atggtcttcc tgaagcatgg caaaaaacta
    53881 ctgatgagga aatcaacact caattagact tattccataa gtttaataac acatctaatg
    53941 agaggattaa aatatggttt gcattaagaa ctatttttaa tacaactgaa gaattacttg
    54001 ttaaaactaa ggaactagct gataaataca atacaggtat acatatgcat attgctgaaa
    54061 tagctgatga aatttcattt gtaaagcaaa acaatggagt tggaacagtt gaatatcttg
    54121 ataaactagg tgtattagga ccaaatcttt tagctgctca cacagtttgg cttactcata
    54181 aagaaattga tttatttaga ttacatgatg taaaagtttc tcataatcca gctgcagcca
    54241 tgaaagtagt tctaggattt gcatcaattc ctgaaatgtt agaaaaagga atacctgttt
    54301 caattggtac tgatggagct ccttcaaata atagaatgga ccttatgagg gacatgtatc
    54361 ttacatcact aatacataaa ggaagaactt taaacccaac tgtcgtacca gctgaagaag
    54421 tcttagaaat ggctactata aatggagcaa aatgtgcttt actagaaaaa gaaattggta
    54481 gtcttgaagt aggaaaaaaa gctgatatga ttattctaaa tccagataca attcattgtt
    54541 taccaatgca taatccaatt ggaaatatag tttattctat gactagtgaa aatgtagact
    54601 ctactatttg tgatggtaaa tggttgatga aggaaagaaa agtattagtt gtagatgaat
    54661 ctgaattatt aaataaagtt aaaaaacaag cttctaaaat aaaagataaa gcagaagtta
    54721 aaattccatc taaatttaaa attataaaat aacataaatt tcaattgttt tgtaaatatg
    54781 aatatataaa tatatttata tacatcatat atacaaaaca attgtttttt tattttatat
    54841 tcattagcat tgctcataaa atacaccata attccagaaa aaataaccaa tcagttagga
    54901 ttacaccatc taagcaatat ataaacgtct tagtttataa gttttattct actcttatct
    54961 aaaaccatct ttaaagagtt ttcaactgtt tcaattacat ctttataact caagtacaca
    55021 tttgcgtaga tacaatcttc atataaatta tattcagtta ctctacaata cagcagtttt
    55081 cctccatcta ataaattgct caaaatatag ttttcttttc ttgggacata gcctatcaca
    55141 tatccagttt caccaactat tttaatagct ttttcatcat atagattatc tttctctcta
    55201 gttaaataat atatcttact tttttccaat tctttttcaa gatattctct atttctaaac
    55261 cttgaaccag caacagctat tgaagtcaaa taaatatcct taccatgttc atctactttt
    55321 attttttcaa tatttacaaa ttcttttttt aaattattac tttcatataa tactcttctt
    55381 aattcatcct tcaatataat atttttttct ttttcatacg cttctttaac aatttttaat
    55441 tcttcaagag atagtttctc tctgtatctt tttaagatat ttatggattc ttttcttact
    55501 tcatttatat ttccaaatat tccttttaaa gatatattct ttccttcagg atatagtgat
    55561 ttacttcctt taagcacaat aaaaaataac atatcatcat aatattcttg agtcaattta
    55621 tctttttcta tatctttcat ttttccaatt aaatcatcta ttttaaacgt ctcttcaaaa
    55681 aaatttaata attttaatct agaacttgtc gttccctttt tagatatatg ccaatatacc
    55741 tcaaaatctc taatatctct attcagatat ggcaacaagt catcaaaaga taagttcaca
    55801 tcataaattt ctgacatttt tataatatct tctgtttttc cactagcatc tcttaatgct
    55861 tcaaaatata tatttttcca tttttcactg agcaagatat catttatttc tttttcaaat
    55921 tcaatcttat tgcactctat attttcatct tttaagacgt ttatagctat taggaaaatt
    55981 gaatataaac tttcaaagtt agtcccataa tttactacag taggtaaaaa tcgattcact
    56041 aattctaatt tattacctat atatttaaat tctacactta gcaagtaatt gcatataaga
    56101 catgctaaat tatttatctt ttctttatct aaatctcgtt tttcaagata ttcattcaaa
    56161 tctacaattg aaataatata gttcatcaat aatcgttcgt actttgtatc cttataacca
    56221 tcttcaatta gataggaatt tattttagaa tctaaatttt ccatattaac aatagcaaat
    56281 acttttattg aacctgtagc ctttttagat aaattaaata aatatgtatt gtaaaattca
    56341 agttttttaa tagtattact cagataaaat acgtattctc cagatttaga aaatgtatct
    56401 acaacttctc ttaagttttc tacatttaga tatttctcac ttaaaactaa ccctagtttt
    56461 acatactcaa cttttttact cttatatatt aattctttag ttaatttata taaccatttc
    56521 tcatcaataa tcatttcttt taccaaagta tttatctttt tcataaaaat ttcgaaataa
    56581 caaattaaag acttagaatt actatcctcc aataaataaa tttcattaga ttcactttta
    56641 tacatattta aaatttcatc tactagatta tttgcaagct ctacttgttc tcttaacggt
    56701 atactttcat atatacatag gtaattcatt tcaaatgatt ctttgtatcc atcataacca
    56761 ttaaattcct gcaatcgctt aaaaacattc tccaccaaat tatcctcctt tacatgatgt
    56821 aatttatatt gattatacta cttatttcgt caagtttaca tttatacgca aaaaaatatt
    56881 actagaaatt gaaattctag taatatcttt attattaatt atgtaaatac cctatcttat
    56941 aactgtaaat aatatcctta ttaattttaa ttacttttaa taaaaaccta tcctagattt
    57001 agacttctct atgcatatat tatactaata ttagacatca taatcataca ctttttcttt
    57061 ttcatatctc atgtttacaa acaatgcaag taaaattcca acaaatgtta ttgccacatt
    57121 aaacaataca acatattttg gtccattaac tccccctgat tttgtaataa tacctgctat
    57181 atttaaaata acatagtttg ctatactaga tgcaatcata actatagatg ttatttttcc
    57241 tttattagtt ggaaacattt catttgcagt tgacgttgtt aactgaagaa cacctcctgc
    57301 tgctgaataa cctattacaa atccccctaa catacaaata gttggagttt gaacaaaata
    57361 tacaactaat agcataagta aagctattat aggatatata actaatattc ttattggttt
    57421 aatatatttt ttaataagta aagaagttat taatactgca catattactc ccattgagta
    57481 aaaggattga atttttgtag ggtcagccat cccatacaat ttacccaatt cctgattaca
    57541 atttaaccat aatacaaatg tagatgtaca tgtaaatcca atacaaacaa gagctatact
    57601 tgttggtgta aatttcatct tctctgattt aactgttttg cctttgttat caataacatt
    57661 attagctggt ggaaatggta acacagctat caaaatggca tctactacaa taagaatcgc
    57721 tgttactata aaaataactt taaatgatat tgaatttgct gcaacaaatc caattataaa
    57781 aggaagcaaa aattgtgcta aagctattgt aaatttagta aacatatttg ctattgttcc
    57841 taaactagca aatatctcca tacaagaagg ggttacacag gtatctaaga atgaatttgc
    57901 tgcccctcca attattgcaa atacatatgc tatataaaaa tttggtgaaa atacaattcc
    57961 aacaaagaaa attgcatgta gaaagtttcc tataagacca cttacttttc ttccatactt
    58021 atctgaaata ggtcctgcaa atggataaga tataagtctc cctaatccta gtgcagcaat
    58081 aacagctaaa acaatactta catccaatgt tccatctgat aatgttttag ccccccacat
    58141 tgatgaaaat tctggtttgt attgtcctaa aattgaaatt ccaataccaa gtaaaaaata
    58201 tgaaaaatac aacgctatgg cagtaggata atatttttta ttgttcataa tttttctccc
    58261 attcttgtta atttattaac atttttgtgt acaataaact catccccata atggatttaa
    58321 agtatagtca gttaaagctt caaatttaac tggactatga ggcaaaaccc actatgacaa
    58381 tttgtaattt attattaaaa atattgaaat acgtatgttt tttcattgtt taagatatta
    58441 ctcttatcta tttaaagcat aattcattaa cttcttctac aggcatttct aatccagtat
    58501 atagattaaa agcctctgct ccttggtata ataacattcc taatccacca atagccttac
    58561 atccattagc ttcagcatct tcaatcattt ttgttttctt aggattataa acgacatctg
    58621 ttactactaa gtcttttctt aaaacactag tatcttttat atttgtttca ttgtcataag
    58681 gcttcatacc aataagagtt gcatttgtca atatattact tgattgtatc tcctcataaa
    58741 gtttgtttgt atcttctaaa tcatatagat taacaacaca ttctggtaca tcttttttta
    58801 tattctcaac tgtttgctct gctcttttat aaaaatcatc cttaggatta aagatagata
    58861 tttctcttgc tccatctaaa gcacattgta cttgtatagc agttgctgca ccaccagcac
    58921 ccataattgt aatcttttta cctttaactt ctaccccatt ttcttttaaa ttacgaacat
    58981 agcctactcc atctgttata tgaccaacta actttccatt gtcatttaca attgtattac
    59041 atgctccaat tatacgagct gctggagaaa gttcatccat atattctgta acagcagatt
    59101 tacatggcat agtaacattg gctcctttta tattaaaagt ttttattgct aaaagtgcct
    59161 cttttacctt atctactgtg atatcaaagg ctaaatatct ataatctaaa tctaatttct
    59221 taaaactata attatacatc actggtgatt tagagtgacc aaccggtgta cctattaatg
    59281 caaataatcc tgttctacct gaaatttcca taactataat ctcctcccaa tattatcatt
    59341 ttctttgcaa ataacctatt cagttattta caaagaaaaa tttatttatt atttatatat
    59401 ttaatgctac ttcaaaagct tcttttgttg catctaatgc cctacgagct tttactgcat
    59461 caccaacaat ataagtttct tttacaactt cttttataac ttcacttaat gggtcgtaat
    59521 tacgagaacc catagcaagt actactgaat caaaaccttt taaatcatgc tctgtgccat
    59581 ctgtaagtaa atagtcgaca ccatcatcat aaaatttaga aacttttgca ccagtaatgg
    59641 tatgtatatt ataattttca aaatcattca taaggaattt acggtgttct gaaattacat
    59701 ctgcaccaac ttcttctcta agctcaataa cagtaacctc atgttcttgt tctccaagga
    59761 aggctgccac ttcacatcca accattccac ctccaacaac aagtactttt ttcccacaag
    59821 attttttacc atcaagaagg tctacagcat gaattaatcc tgaatcattg attcctggta
    59881 taggaagtac aagtggagtt gctccagtag ctataataac tacatcaggt gatttctctt
    59941 ttataagttc tactgtagct tctgtattag tacatatttt tacaccatat tgattacatt
    60001 ttgaaatata acttctaact aagttagtaa tatctccttt ccctggagga tatgcagcta
    60061 aacgcatttg cccaccaaga acttcagatt tttcaactaa agttacatta tgtcctcttt
    60121 tagcacatac ccatgctgca agcatacctc caacacctcc accaacaaca agaacttctt
    60181 tgctaatttc agctggctta agctctgctt catgtcctaa tataggattt gcaagacagg
    60241 ctataggttt gccttggaac atatttggta cacatccttg taagcatgca atacatggta
    60301 tcatttcgtc tagttttcca tttttagctt tattaggcat ttctgggtca gccaagcttt
    60361 gtctaccgaa tgctactaaa tcacatcttc cttgtctgac cattaactca gcaaactgtg
    60421 gctctgtata acgtccaact gttattactg gtatactaac agcttttttt atttcagtaa
    60481 ctaattctgc actgaatcca gcatgtaaag tcgtaggagc ccacatatat tcatcatgta
    60541 tatgtatact acgtgaaaca tgaagtccat ctattccaca atcttctaga tatgctgcta
    60601 ttactgaact atcgtgtaca tcaattcctc ctggaacatc atcagtgctg tttatacgac
    60661 ataatattgc tagagaattt cctacttttt tacgtatatt ttcaatgata agacgaggta
    60721 atctcattct attttcaaaa catccaccaa actcatctac acgcttattt gttctttgtg
    60781 atataaaact actaaccaga tatccatgag cgcagtgaac ttcaacagca tctgcaccag
    60841 ctttttgtgc acgtaatgca gcatctccat aagattctat aagttcatat atttcttctg
    60901 ttgttattgc tagtggtgta ttacgaccat ttgatgcagg tattgcagaa gcagctttta
    60961 atggatgtcc tgctactttt tcatttcctt cagaaccagc atgttgtaat tgtatagata
    61021 ccttcgaacc tgcatcatga caagcatcta ttacattttt aaaactatct attgtgctat
    61081 catcatataa acaaggctta cgaggacctc cttttgcttt tttgtctaca acactagatt
    61141 ctatagttat taatccaaaa ccacctaaag cacgctcaag ataataagcc ttagaagttt
    61201 cacttaaagt accatctgtg tttgcaaaat tgtttcccat agggggaact acaaaacgat
    61261 ttggaactgt cattgaacca attcttatag gtgtaaacat agaactaatc ttcataaggt
    61321 tttccttcct ttcaagtttt atatttaaaa gttttatatt ataatactct gtatattttt
    61381 atattatata agtttatttt ggagatactt cagaccatgc tttatccaaa acttttttag
    61441 ttgcattaaa tacagtttca gcagcagtgg ataacccttt agatattaga gaatcagata
    61501 ttacttctgc ccctatgact cttggtgata tattgtgttc ttttattatt ttcacaaatt
    61561 cctctgtgtt tccatatcct tcacctggag ccaaacggtc atgtagtgat tcatccctaa
    61621 gtttttcata aggagtttct aaaacatcac acacttgaat tgatactatc ttatctgctg
    61681 gaacaggtgc aaggtcctct gctgtctgct ttgctctagc ccagtgccaa gtatctaata
    61741 taagcattgc attttcacga ttacatcctt tcacaacacg ccatgcagta gctaaatctg
    61801 gtacaccact atatggcata aactcaagac ctataataag ttcacctgct ctgtcacata
    61861 attctcccaa tgcagttata atttgttctt ctggtatcat ctctaataat ccacaattta
    61921 tatgtttaac attaaataag tgagccatat gataaacatt ttgctctttt tctctttgag
    61981 cttccgttct atcttcttct cttccccatt gagttatata ttctacttct gtaactttca
    62041 tatcatattc attaagaatt gcaatcattt cttcatctgt aacacctgca ttttttgcat
    62101 caatataatt ttcagcacgc aatccaatac catcaaaccc agcttctttt gcaatacgaa
    62161 ctctatcacg gaatgaaact tctgttccca atgtataaga actaattgta attggaatat
    62221 taagattttt ttgattattc atagcttaaa tttgccccct ttattttctt tataattaat
    62281 agtattttta attttatatt tttatttatc ctactagtag tattatttta ccttaaaaat
    62341 aaaagtattt tttgatttct atttatctag attttataaa tttattgtat cacgagactt
    62401 tactaataac aaattgataa tttcctatta attcatagat tttgtttata gattttattt
    62461 ataagataat tcttgtattt ttctattagg tcgtataaat atatttatct tataattcag
    62521 acaaaaaacg ataaattttt ttaaaagctt ttattcttac tctataatca tatataataa
    62581 aaatgtaaaa atatcttaaa ggttaacttc tacaaatata taaataaaaa tacctatgaa
    62641 aggatgaaca aaaattgaat ttatatcact tacgctattt tgttacattg gcacatttag
    62701 aacactatac aaaagcggca gaaaatttat ctataacaca accaagctta agtcatgcta
    62761 tttctttact agaaaatgaa cttggggtgg ctctatttga aaaagaaggt agaaatatag
    62821 tccttactaa gtatggaaaa atatttttaa aagatgtgga aaaatcatta gaaattttag
    62881 attcaagtgt aaaatcatta aaaataactg gtactggtga aggacaaata gacttagctt
    62941 ttcttagaac acttggtact gattttatcc cagacatagt gcataaattt ttaaaatcta
    63001 atcctgctaa atcaatagat tttaaatttc atactggtgt aactactgac attattcaag
    63061 gtcttagaga aagaaaatat gatattgcat tttgttcgaa acttgaaaaa gaaaagggaa
    63121 ttgaatttat acctgttgcc aaacaagatt tagtactaat tgtaccatat agtcatccac
    63181 tagctgcaaa ggatactata gatttaaaag aaaccatacc ttatcctcaa atagtattta
    63241 atcagagaag cggtcttaga tatataattg atgatatgtt taaaaaaata aatcaacagc
    63301 ctaatatagt ctatgaagta gaggaagacc aagtaattgc tggattagtt gcaaaaaatt
    63361 tcggaattgc tgtagtccca aatatgaata tgcttagctt tacaaaagta aaagtaattc
    63421 agattattca cccaagttgg gaaagaaact tttacttagc atttataaaa gatagatatt
    63481 tgcctcctgc aattaaaaac tttaaaaact ttgtcattaa aaacgctcaa ttataattta
    63541 ttaataaagg ggttattttt aaatatcctc ttttattctt tttataaaat aaaaaaatct
    63601 atacttttaa aagtatagat tcctaactga cagtcggcat ccgagtctca gtaattatcg
    63661 ttatacaaca gcaactggat tcagttcctg aataactagg ttactcacat tatatcagat
    63721 tttttaaaat ttgtcaattg tatctaacgc attttttcaa gccatggtcc aacaggctct
    63781 acaataggaa cttctttaaa tccccaattt cttatatcat tcacactcgt tggagtatat
    63841 attttgtttc tgacagattt gaatattttg tttttttctc catattgcat acactttgga
    63901 ttagcttcta ttaaccctct tcttgctctg ctaagaggat tacataaaat atctgctatt
    63961 tctaaacctt ctctatagtc agcatcttct tttttggcaa ttataaaacc cttaacttta
    64021 tctcttaatt cttcatctat atctaagtat attgttccat tattaaatac atcaaaaaac
    64081 gccttttgta cttttaagtt tgagacatca tcccttgact ctataactat tcgtgcagat
    64141 tctacagttt cattatttac aaatgaataa aaattctgaa gaacatgtat aaaagccaca
    64201 acatacggtt cctttgaagg tgcataatat ttctttaatc tagctttatc tactgttact
    64261 gatattatag tacactctaa tctagataga aataaaggca actcatcata gaataactta
    64321 atctgtgaat catcaaactt ctcaaatgct cttgattttc ttgatatatc tgtcaaatgt
    64381 attcctatgt tactggttcc aaaacaatac tctttaaatg catccatttc tttcctcaaa
    64441 gaacatacat aatcgccttg acttactgca tatttatatt caaaaattac tcctgtcaat
    64501 gtaaatgggt cttcatgatt tatatcagct cttccacttt catcaataaa cattatatat
    64561 tttttcttta taatcttact caccctctta acatatgatg atagcatcta tattcatttt
    64621 atatgagttt taaaaatatt ccaagatttt tatataactt aaacttaatt ttatactaaa
    64681 aaattgagat gtaaaacaat caagctttta ttgattgaat ttcacatctc aattataatt
    64741 atttttcaat atatgttttt actattttgc aagaatatcc attaatttat ccattactat
    64801 ataagatact ccgcctccta tttgataagg agtttcaact tttttatttg caaatactct
    64861 ttgttgctct gatgataatc ctgaattatc cattaaaact attggtgaat gtaattttac
    64921 agctaatggt ccagctgata aagcatctac taaagcatct gatttactaa ctaatacagc
    64981 ctgtaaatca gtatctccat agaatttttc tattactttg gcattagtat ctactctact
    65041 atctccatat attctatttc gtgaaatatc ttcagtagtt atatcattca tttttgctat
    65101 tactgaatcg ttaattgcac ttggtccacc tataaagtat gcattttcta attttctttc
    65161 tgttagccat ttataagatt cttctgtaat tccatcttta ttgactaata ttataggttg
    65221 tttttcttcc ccagctttag aagctacaga taaagcatct gcttccccat ttccagaaac
    65281 catatatgca gtttttattt cttctcgatt tccaagttct tcagctattc ttgtagcagt
    65341 ttgatatcta tcttgacctg ctattctctt tgtttctgtg ttgaaagtag tttttatttc
    65401 ttgctctaat ttagaactta ttgcattttc tccacctatc aagattactg ttttaggtgc
    65461 taataacttc atttcttcaa cagtttcagt tggtaaatta gctgtattag taagtagtat
    65521 tgttgagtca tagctacttg ctaaaggagt tgctgttata ccatcagcta ttgcattacc
    65581 atttactaat attacagtat ctgaactatc agcattccag tttccaactg aacttatctt
    65641 tttagctgta tcaaatctat ttgcacctat aattgtatcc catgtaggat ttatagttcc
    65701 atcttcatta aaagtataat ctttcccatc tattttttga gaaccagtta gcatctttcc
    65761 atctttgtct aaatagtaag acttaccatc tatttgttgc catcctgtct gcattattcc
    65821 tgttttgtca aagtaatact tattaccatc tatttcttgc catcctgtta ctgctaaacc
    65881 atcagatcct agatagtatt tctttccatt cttttcttgc catcctgttt gcattactcc
    65941 atctgagtta aagtaataag tttttccatc tattactttc catccagata ctcttgctcc
    66001 atcagttcct aaataatatt ttttgttatt aattgttttc catcctgttt gcattactcc
    66061 tgaagcatca aagtaataca tttttccatt tacttttagc caactattct tttggtatgt
    66121 tccatcagat tttacataat atttcttacc attttctgtt ttccatcctg tttgatttag
    66181 atttatctta tattttgccg ctatctttac atagctgtcg ttactataat ctataattac
    66241 atctgaacct acaggaactt ggtcaaataa ccatctaaca tctttattgt gcattcttat
    66301 acatccacca gaaatatgct ttcctataga actctcatta ttatttccat gtattccata
    66361 tgtatctcca taagttcctt ttaatgctaa tcccatccat ctatctccta atggatttct
    66421 tggacttcct ccaggtatat tacctttata atatggtcta ttttttatct tgttaactac
    66481 ttttgttttc cctgttggtg tttctgaccc ctttttacct gttgcaactc taaattcttt
    66541 tacaagttta ttatttacaa aatatcctag agtatttttt cttgaattta ctataatcac
    66601 atgtttactg gctgcgcttg attctggtac gccacatgca aatactaaaa ctaaagtcag
    66661 tgctagtact aaatactttt ttagactttt tttcactata acttccccct cttttagaaa
    66721 cattactaca tgtgtctaat tataacataa aattaccaat accttatatt tacaaatttg
    66781 ttacatttat acatataagt atgtattcta ctcttcatac ccattaggat tcatactttg
    66841 ccatctccat gaatcttcac acatctcttc aagttcatac ttagctttcc atccaagctc
    66901 tttttctgcc tttgaagaat ctgcataaca catggctaca tctccagccc ttcttcctac
    66961 aatcttatat ggtatttctt ttccacttgc tttagaaaat gcttttacta aatcaagaac
    67021 actatacccc tttccagttc ctaaattata aacaacaagt cctggatttt cttctaattt
    67081 ttgtaatgct tttacatgac cagcagctaa atctaataca tgtatatagt ctctaactcc
    67141 agttccatca tgtgttggat agtcattacc ataaacactc aattccttca atttacctac
    67201 tgctattttt gttatataag gcattagatt gctcggaact ccatttggtt cttcacctat
    67261 tctaccactt ttatgagcac cgactggatt aaagtatctt aaaagagcta tatccaatga
    67321 cttatctgct tttgatatat ctactaacat ctgctctatc ataagtttag ttcttccata
    67381 tggattggtt acagaaagtg gaaaatcctc taatatagga caagtatgtg ggtctccata
    67441 tacagtagct gaagaactaa atacaaactt tttaacacca tattctctca ttaattcaaa
    67501 taaatttaag gtacttatta gattattgct gtaatattca attggttttt ctactgattc
    67561 accaactgct tttaaagctg caaagtgtat aattgattca atattatttt ctttaaatac
    67621 aacatgcatt tcatctttat ttctgatatc aatattataa aattttactg gttttttaga
    67681 taattccttg attctatcaa ccactattga gttgctatta cttaagttat caactataac
    67741 aacttcataa cctgattcta aaagttctat tgctgtatgg cttcctatat atcctgctcc
    67801 tccagctact aaaactgcca ttgtaattac ctcttttcta atatttattt ttcacttact
    67861 ttttttctca tatagtccat taaatcatct tttaaatttt ctctctttag agcaaagtct
    67921 attgttgcct ctaaaaaacc aatcttatct cccacatcat atcttctacc ttcaaagtta
    67981 taagcataaa tagcctcttg ttttccaaga gtttgaagtg catctgtcag ttgtatctct
    68041 ccacctttac caggtgtctg tttctctaat atgctaaata ttgcaggagt tattatatat
    68101 cttccaagta tagctatatc agatggagct tcttcaattg caggtttttc aaccatatct
    68161 ttaactttat atactctatc ttcgatatgt tttacatcca atataccata tttattagta
    68221 tcttctttag ctatcttttg aacacctaat acagttgttt tatactcatt ataagtatct
    68281 attaattgtt ttaagcacgg aacatctgaa tctactatat catcacctaa taatacggca
    68341 aaaggttcat cacctataaa actttttgca cagtaaattg catgtccaag accttttggc
    68401 tctttttgtc ttatataatg aatatttacc atatttgata tgtctcttac catttctaac
    68461 atctctgtct tacctttttg ctctagttct aactctaatt caactgattt atcaaaatga
    68521 tcttctatag attttttatt tctacctgtt attataagaa tttcttcaat tcccgattct
    68581 atagcttctt ctattatata ctgtaaagtt ggtttatcta ctataggaag catttctttg
    68641 ggctgtgatt ttgttgctgg taaaaatcta gttcctagcc ctgctgctgg tattattgct
    68701 tttttaactg tcatctgcat tttttcaccc ttcttcgtaa attttctatt gtaccaaatt
    68761 aatataccat atttatactt tttcttcaaa ctctatatta tcccaatatt taatgctata
    68821 agataatata aggtagatga aatttcatct acctttagtt ttataagtta atattgtatt
    68881 gtttatattt tatccaaaac ttatacaggt actaaatttc atctaagatg ccttttatat
    68941 cactatctat atcttcatct agataagaat ctaaatcttc taagtcaact tctagttctt
    69001 gatatgtcat atcaacactg acatcctcat ctatatccat ttctgatatt aattctccta
    69061 aaatactatt tccatcagaa tctaaaccac tatctatatc ttcatctata tagttttcat
    69121 ttaaaatttc atctaaatca atctcgtaat aaacttcatt atttttttca tcccctgagt
    69181 ccaatcctaa gaactcatag ttaaaagtcc aaacattgta tttacttgac atactttatt
    69241 cctcctgtga aaaacatatt ttcatctagt ttattggttc cataatcaac agagttatat
    69301 attttttcaa ttatgtcttt tcttctttct tttgtactat tatttaatgt caattgttta
    69361 aatacatatg tatttgttat tctctcgaat aatatttctt ttatactatt atcatcaata
    69421 tttctatagt ttttccacaa taactcaaat aacttaaaca tttccctact agtttcatct
    69481 acataataag gatacatatt ttctactaaa tggtttaatc ttgatatggc ttgttttaaa
    69541 aatacatcaa gacttgcact ttcactttct tttaacattc tataattgta tttcttctta
    69601 tcttctcctg aaattacaaa gatgatattg tctaaacttt tttcaacttc atttaaataa
    69661 ctgcttatat tatatgataa gtcagacaat agatttttaa tctgcttaaa cacttgtaca
    69721 tcaagtttag tattatactt ttcaaacaaa tctatttctt gattttctaa tattcttggc
    69781 atatatgctg acaataaatc caaattgttt ctttgttctt gtatttgctt ataaagtgaa
    69841 tttataactt ctattcttat ttcatcattt aactcttttt ctaaaatctt atcaaattca
    69901 gatttcatat agtaaatatt tccaaagaaa ttaaatatta tcatatcatt catagcttta
    69961 gaccaattct tatatatcac ttcaatagaa ttttctttaa gtagaggttg ctttgcatat
    70021 ataaatacat cttgcataag tttttgaacc atacttttac ttaagtttaa aagtactttt
    70081 tgattattaa attttatttc cgtttctaca aaattagaat tttcgttttc aagttcttta
    70141 ttaattacaa tgtcttttat atcactattt tttatagata tgatttcttt ttgaaaagac
    70201 tttagaatag tcaagctatc gaaatcttct tgaataaaaa atggagcatg ttttaatgta
    70261 tatcccacta tttcattttc tatatctttt aggtcatcta tttgcataat ttctctattt
    70321 ttatcattta tatgtaggtt aaatacattt ttattatcat ataatattat atcttctcct
    70381 aaatttaact tagaacaatt atctttcgct gactttacaa tagtcttctt agatttctta
    70441 tttataaaaa ttaattggtc ttgatatttt actaaaagca tgtttgtgtt tttataatca
    70501 aatccatcta tatttcctga tatcttgcag aatactattt cacaatcttt aggaagattt
    70561 cctatctttt ggttatcttt aactctctca tttaagtcag atgggactac actatctata
    70621 ttgttattaa atatagatac agaccttact ataatcccct ctctttccat atgaaagtat
    70681 cccttcaatg acactctttt atcttctaaa atgtatcttt ctatatcatc aaaatttatt
    70741 tcaaatctat ttttcccact gataaatata aacttctcat tatctttatt aattccaccc
    70801 atataaaact tattgtcatc taaacttaat atagtcatat tatcctttag atagaatata
    70861 aattctcttt gacttttgca gattaaatca tattcatcca aagttatttt catagtcaaa
    70921 tttgctgtaa catttttact tgaattttca ctttttatgt aaaaaggcaa gttatttcca
    70981 tagacaatta tttgagaatc ttctaaaact gcctctaatt tttctttatt gtctgaaaaa
    71041 ctatatatat attttacacc tgtatcctca ttaacttcat ctgatttgct gattattata
    71101 ttccctagat ttgttatatg aagcttttta tattcttttg agtatctact tatgccacta
    71161 agctcaaacc catctgaaag ctcatatatg attttttctc ctaatttcaa cataccttca
    71221 ccacctaaac agaattataa gtattttata aaggtgaata aaatgtctca aaacaaataa
    71281 tatttttttt aatacttttt attctgagac atagtttctc cttttttata atgctctaag
    71341 caccttcaac tatttcttca taaagtttat ctaaatgttt aacatattca cgatatccag
    71401 atttgttctt taactcactt cttaaatctt catatttttg tttaagttct tcagcactca
    71461 aagaaggagc tgattctttt aattcttcta acttataatc atagtactta tcatacatag
    71521 ctatatatgt atcaatagac ttcttagcta gttcattaca tttttcttgt gcttctccat
    71581 attgagaata atcacctatt tttattttat agtatccatt ttcttgaatt attgttgaag
    71641 aaataccttt agcctcatat tcttttgctg tttcttttgc tgttttttca actttaagtg
    71701 aacctgcata aacagtgtaa tatacacctt taccatcttt atatgcttcc atttcttttg
    71761 ctttcttttc agcttgtgct ttttcttgag cctctttttc agcttttgcc ttttcttctg
    71821 cttctttttt ctctttttca gcttgtgctt ttttctcttc ctcagttaat ttattgttag
    71881 cttgttgctg agttgatgac tttggaatat tctctttatc atttttctta ttattgccta
    71941 ctgttataaa atatcctaca ccaacaataa ccactataac tactgctata atagtttctt
    72001 ttaatctact cttcttagaa acaacctctt catcatctaa agaatcttct ttatctgata
    72061 cataattttt catttctttc ttgttttctc tatatttgtc cttagaagaa tttttagatt
    72121 ttttattact attttctttc tttttaatag gtattactac tgatttttca ttttctaatt
    72181 tttcttcttt tatttctttt gcttttttat cttctaagtt tttactttct ttttcaagct
    72241 tcgattcatt atttgaagat actttttcat ctaagttatt atttattggt ttttctattt
    72301 ttacactacg ttcttcttct atatgttgac ttggttcttc ttgttttatt tcttttaatt
    72361 cattttgctc tatttcttct gattttactt gatgattttc aactggttta tctaaaatta
    72421 tatcaggaga aatatcattt aaattctctt cttcttgttc aacttcttca ttgtcttttt
    72481 taataaatcc aaataattta gccttctttt tactcttttt attttctggt tcaattatat
    72541 cttctttatt gctgtcgtac tctttatctg tagtatcttt atcttctaca acgtcaccta
    72601 tatcttgatt attactatct attccttctt taaccccttc ttcagcatca tcttctattg
    72661 aaatactact tctaaagcaa atatctttat ctgcattttt tatcatgtaa atgtattctt
    72721 caatatcgat atctttattt cttctagttc tttttgatgc aatttcatga ttttctaatt
    72781 cactatagtt atcttttatt agattctgtg ctttattcca tgtatcttca ctaatttctg
    72841 ttttattttt aattacatag tccacaaatt ccttaaaatt ttcaggacca aattctccaa
    72901 ttatagtcag tctcattgca ccttctataa ggtctctatt tcttctcttt aaaaattcta
    72961 atacaaccgt tgcacaagca aaatctttaa taatttcttt gccaaaacca tatccttcaa
    73021 cagaatgaag ttcttctaat ccacataact tcttatattc attgtgtatt gtttgagata
    73081 cactttcatt atttaagcta tttaacttat ctataaactt cgattctata tcatttgatt
    73141 ttgattcatg ttttactttt gaatttttaa tttcatttag tagcatgtca ttttctgaat
    73201 tatctttacc taattgcaaa tcctcaattt cagttgcttt tatttctact ttgtcttgtt
    73261 cgttattctc ttccacatta ttaggtacca catctttatt gctagctaat attttgttta
    73321 cacagaatat aatttctctt tttaattctc ttttcgcatc tgcttgattt ttaagaaata
    73381 aatctccaca ttctttcttt tctaaactta tttttctaag agatatatta agaaggtctt
    73441 tatataggtt taaaacctta taatcctttt ctaaacgtct tcttctctct gatagttcca
    73501 ttttatcata agctaaaaaa ctatttaaat cattggcttt tagagagtct aatccctctt
    73561 tcatagcctt atttacatac tttctacatt ttgctgtagt taattctaaa tctttttcta
    73621 attcatctat ttcaggtatg tacttatcta ctatccattt gccaataagt ggttctgtat
    73681 ttcttgctaa tgtcttataa aacaatatat taaattttaa aagctctgca tattttgctt
    73741 cattaaattc tactttttca aatttctttt ccaaaacacc atctagcttt tcatttattt
    73801 tagactcttg ttttaaaaaa cttgctgtga catttaaaac agtgtttctt attatattat
    73861 tttcactcaa aaccttcact ccttaaatca attattttat tgtaatattt acattgtgca
    73921 aagttgctaa tttgattatg atatctaaat aattatttac taaatttgct acatcttata
    73981 tcatatcata ttatttacat cattttactt tttcttttta tatctatctt atattatacc
    74041 atttttaata tctgtactaa cttatattac aatattcctc aaaattttaa aagtagatta
    74101 gacaaattta caaataaaaa aacatcagtt taaactgatg tttttgacta tcgaaataat
    74161 taagcaagtc tataagcgga gttctgtatt agataatcat ctttctaggc ctattgtcac
    74221 caataggctc aagcgaccta cctaccggag agtacgagca gcactcttta ttcctatctt
    74281 ggtcttgctc caggtggggt ttacatagcc aactagtcgc ctagctgctg gtgagctctt
    74341 acctcgcctt tccatcctta ccacaatagt ggcggtttat ttctgttgca ctatccttag
    74401 gatcgctccc actaggcgtt acctagcacc ctgctctatg gagctccgac tttcctcatg
    74461 taagattaca tgcgattatc tggcttactt aatatttatt ttacttagtt atgttaacac
    74521 aaattctttt acatgtcaaa gtaatattat actaaaaatt taaatttatt caaaaatagt
    74581 gtaatataga tatataaact acatttaact cgaggtgata tattgaaaaa attatataga
    74641 atagtaatta acattatact agtattagta atactttaca gtggatttaa tatatactca
    74701 aaacttacca aatacaatca tgatactaaa atatcctcag aacttcaaaa aaaagaatat
    74761 aaaaaagagg atttatcaaa gattaacagt gattttaaat tttggctttc tgttgagaat
    74821 acaaatataa attatccagt tgtacaatct aaagataatt cttactatct tgacaaagat
    74881 ttttataaaa aagattctat ttctggtaca ctgtttatgg attatagaaa taaatctatt
    74941 gatgacaaaa atatcataat atatggacat aatatgaaaa ataaaactat gttcaacaac
    75001 ctaaataagt ttaaagatgc tgacttcttt aaaaaaaata ataaaataaa aataaccttg
    75061 aatggaaaag aatttttata tgatgttttt tctgcttata ttgtagaatc tgattatgat
    75121 tatctaaaaa caaattttaa taatgaatct gattatcaaa attacataaa tgatattact
    75181 tctaaatcat tgtataaatc tcctattaag gtaaatagca atgataaaat agttacactt
    75241 tctacatgta cctatgaatt tgatgatgcc agaatggtga ttcatggtag attgatttaa
    75301 aactcacaga cacagtttaa aacaataatt ttaaactgtg tcatctttta tacctataat
    75361 ttataaatta gaccactaaa agtatttaat acaaaataac aaatacatca aacaataaaa
    75421 aacaataaaa aaagactatg ctaaaaacat agtctttact ggagctggtg ataggaatcg
    75481 aacctacaac ctgctgatta caagtcagct gctctaccgt tgagccacac cagcacacct
    75541 attttattgt aaattagtaa aactaatttt taaaagttaa cac
//
LOCUS       DAEORM030000014        75433 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.014, whole genome shotgun sequence.
ACCESSION   DAEORM030000014 DAEORM030000000
VERSION     DAEORM030000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 75433)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 75433)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 75433)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..75433
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.014"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            37..1170
                     /locus_tag="KRH23_001312"
     CDS             37..1170
                     /locus_tag="KRH23_001312"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M56 family metallopeptidase"
                     /protein_id="HHS5224597.1"
                     /translation="MSNFILNGIFRTVIVSSLSILLILIFKKNVFKRFSKKFNYYIWM
                     IVVIKLFLPFTYYTFTINILRSKKHININNINLEGFNNVSTISNNIILYTWIITVVVY
                     LIYTIFKYIKLKNLINDLSYDVDDREIVNLYKNILEEFNITKDIKLKYSYEVETPAFF
                     NSCVLLPPHEYKLKELDWIFRHELMHFKSRDLYLKYVILFLKTVYWFNPFIYIMDKHI
                     DLDCELYCDERVLKNRNSEEKKDYALTILNAMRKGSNTSNKFIAGLHKQSDIKKRVMN
                     MFNEKYKNGILMALTLCLLSSITFLKVNSTSIVNLNVLPKGFEDLRTVSSIRFSVIGF
                     TYADAPKNMREEYKINCESLGLIPKDSDKIEVGIEYYDSLLND"
     gene            2085..3083
                     /locus_tag="KRH23_001313"
     CDS             2085..3083
                     /locus_tag="KRH23_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NlpC/P60 family protein"
                     /protein_id="HHS5224598.1"
                     /translation="MKKKILIPVFASVMALSVSSIVNADEVNDSSQNKDDKTNTELNL
                     GEYKEVKYKVAKIKDGVAIKIREEGQVQNIAYSGDEFTVLGTQGEWVKVKVEDGEGWL
                     ATRYVDISEGVGYTNADKVNLRKDKSESSEVIEELEKGSSLLVLEDNGDWLKVKDGET
                     EGYVKSSYISDKAPVIEEPQVNPSIDQNVDSTNNNQQNNNSNVPTANSNAVQAVLNLA
                     YSKQGCPYVWGAEGPNTFDCSGFTQYVYRNAVGKNIPRTSKAQSKYGQTVSKANLQPG
                     DLVFFTTNGSGSVSHVGIYVGGGNMIHSPSTGKTVSVTSINSSYYTARFVTAKRIL"
     gene            3379..4299
                     /gene="pyrB"
                     /locus_tag="KRH23_001314"
     CDS             3379..4299
                     /gene="pyrB"
                     /locus_tag="KRH23_001314"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004070 - aspartate carbamoyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase"
                     /protein_id="HHS5224599.1"
                     /translation="MLKSRNLIQPEDFSIEEIDEILELAQKIIDNPSKYSRICEGKLL
                     ATLFYEPSTRTRLSFESAMNRLGGRVVGFSEPNSSSASKGETLGDTMRIVSGYVDIIA
                     MRHPQSGAASEAARYTEVPFINAGDGKNQHPTQTLTDLLTIKSLKGTLESHTIGLCGD
                     LKYGRTVHSLVKAMARYKNTKFVFIAPEELKMPDYIKEAIKGHAYYETNNLDDVIGSL
                     DVLYMTRVQQERFEDKSEYERLKNYYILNKAKLEKASKDMLVMHPLPRVNEIDIDVDS
                     DDRAVYFKQAKYGMYVRMALIIKLLGINED"
     gene            4338..5030
                     /locus_tag="KRH23_001315"
     CDS             4338..5030
                     /locus_tag="KRH23_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HHS5224600.1"
                     /translation="MYKILENIYIGEDMYRMKVKGNFEGKMGQFYMLRAWDTYPVLSR
                     PISIHDIDEEGITFLYKVVGEGTQILSNLKVNDNIKLEGPYGNGYDKVDGKVALVGGG
                     IGVAPLYLVAKNIKNCDAYLGFREDVILEDEYKQVCNKVYTTVGNTFVTDIIDVEKYD
                     YILTCGPTPMMEKLVKMVEGTKTRIMVSLENHMACGVGACLVCTCKTNGGNKKTCKDG
                     PVFWGEDVIFNG"
     gene            5023..5925
                     /locus_tag="KRH23_001316"
     CDS             5023..5925
                     /locus_tag="KRH23_001316"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004152 - dihydroorotate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HHS5224601.1"
                     /translation="MGNLSVKFGSVEFKNPVIMASGTFGFGKEYNEIYDIQKLGGISS
                     KGLTLNKKPGNNGMRVHETSSGMMNSVGLENPGVQGFIDYELPFFSKLDLVRIANVGG
                     GTLEDYLLGVQMLNDKPVDIIELNISCPNVKAGGMAFGIKNEVAREVVREVRNITKLP
                     LVIKLSPNAEDIVGMAKVCEEEGADGVSLVNTFKAMAIDIKNRRPVFENVYAGLSGPA
                     IKPIALRMVHEVCKNVNIPVMGMGGITKATDAIEFIMAGATCIQVGTANFMNPRIGIE
                     IIDGINEFMDREGIKSLDEIRGII"
     gene            6010..6594
                     /gene="pyrE"
                     /locus_tag="KRH23_001317"
     CDS             6010..6594
                     /gene="pyrE"
                     /locus_tag="KRH23_001317"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004588 - orotate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0019856 - pyrimidine nucleobase
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HHS5224602.1"
                     /translation="MSKVDVVDILKKSDALLEGHFLLSSGKHSNRYVQCAKVLRFPEY
                     AAEVLSTVVEQIKDLDIDLVVGPAMGGVIVSYELGRQLGKEAVFTERKDNTMELRRGF
                     EVKKGAKIIIAEDVVTTGKSTMETKRVLEALGGEVVGVACIADRTNHDIGMPIYSAIK
                     LDIQVYESDECPLCKEGKLPVVKPGSREFKELGM"
     gene            6809..7735
                     /locus_tag="KRH23_001318"
     CDS             6809..7735
                     /locus_tag="KRH23_001318"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ketopantoate reductase family protein"
                     /protein_id="HHS5224603.1"
                     /translation="MKNQLNENHKKVVFFGVGAVGATFAEQFFNSKYDFKILCDNERK
                     KRYLEEGFIINGKRYDFDYVTKDEYKQEADFIIIGLKYNNLKENIKELDGLVGKNTVI
                     MSLLNGVDSEEIIGERFGIEKMVYSYVTNIDAKKINNNIIHTTNGIIVFGNKDNSEDR
                     KTNIITEVFDDVNIEYTLSKDIQRDMWWKYMVNIGVNQTSAILGAPYGVFQSSEHLRE
                     LAKSAMREVVAIAQAKDISLTEDDVEHSLHRILEHSKEGRTSMLQDVEAHRLTEVDMF
                     SKNICKLGKKYNIPTPINQTFFYMIKVIESRF"
     gene            complement(7787..8677)
                     /locus_tag="KRH23_001319"
     CDS             complement(7787..8677)
                     /locus_tag="KRH23_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HHS5224604.1"
                     /translation="MFEELKTFVAVVEYKNFTKAGEYLNLSQPSVSKHIKNLENYFKV
                     VLINRSIKQKTIFITESGQILYKRAKEILNLLNITYHDVSQVSDAITGHLKIGASLTI
                     GEYILPNFLALFSKKYPDIDVEVFIKNTSIVSSHVKDYILDIGLIEGTCSSPSFIQEY
                     FFEDKMVLALPYKSHLLKDFSFDKLQNQKWIVREDGSGTRDYLDMFLSVKEIIPKSMM
                     VFGSNYAVKESVRNNLGITIVSNLVTSLPVLNNELSVIELGSSYNRHFSYIFPKDITL
                     SKAATIFIEELKIFSNLNSI"
     gene            8865..9896
                     /locus_tag="KRH23_001320"
     CDS             8865..9896
                     /locus_tag="KRH23_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family protein"
                     /protein_id="HHS5224605.1"
                     /translation="MLKKKSSLTLKTIREILPGLFVSVLVGYISIFISILIPKVGAAS
                     ISIFLGMFVGNLFLNQKVFQKGYKFSETDLLSYSIVLLGATLSVSTLIDLKVSGILFI
                     ILQMTITIIAALYIGKKLGFEENFRFLMASGNAVCGSSAIGATVPVVNATDKEKGIAV
                     TIVNVTGIFLMFLLPIISQFLYSHELVKTSAMIGGTLQSIGQVVASGAIVGENVKDLA
                     TIFKIVRVIFLVVVVLVFGHMKNQSNREILEEEKDEIKKKKVTIPWYVIGFFITCALF
                     SMNIIPKEVSVLCKEISNKLEIIALAAIGLKVNVKDLVKQGKEVSLYGLFVGTVQVVS
                     AVVLIKIFI"
     gene            10190..11065
                     /locus_tag="KRH23_001321"
     CDS             10190..11065
                     /locus_tag="KRH23_001321"
                     /EC_number="3.2.2.-"
                     /EC_number="4.2.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0032993 - protein-DNA complex [Evidence
                     IEA];
                     GO_function: GO:0019104 - DNA N-glycosylase activity
                     [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase family protein"
                     /protein_id="HHS5224606.1"
                     /translation="MNVYEKGNGVILEGVTDFDPVHIFECGQCFRWHKQEDGSYTGVA
                     KGRILNVKKENDKIYLNNTNLKEFNSIWYNYFDLGTDYTEIKNKLKNMDEYLNKATEF
                     GWGIRILRQDGWEMLISFIISSNNRIPMIQRAIENLSRKFGKYIGEYEGNEYYAFPTP
                     EELNKASQEEIRACQTGFRDKYIKSTTQAVIENNDEVSEYTNLSTEDCRKELLKFNGV
                     GPKVCDCIALFGMQKYDSFPVDVWVKRVMQEFYIDEDMSLPKMRTYGIDKFKEMSGFA
                     QQYLFYYARELGIGK"
     gene            11083..12573
                     /gene="cls"
                     /locus_tag="KRH23_001322"
     CDS             11083..12573
                     /gene="cls"
                     /locus_tag="KRH23_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008808 - cardiolipin synthase activity
                     [Evidence IEA];
                     GO_function: GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA];
                     GO_process: GO:0032049 - cardiolipin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HHS5224607.1"
                     /translation="MGVIGTIFLFYLIISYLAGAIISVIILLENRDPAKTMSWLLMFI
                     IFPGVGLMIYAISGRNIRKRKLFKTQKLANNIKEKKLFDTLEKITEIVELEKESIKQN
                     KLLRDEEDGSYRKRVINMLLKTGMFPFTKNNKVDVFVDGNEKFKRLIEDIREAKDHIH
                     LEYFIIKDSEIGRVLKEELIKKAKEGIKIRILYDDVGCWRFWFNRKFFREMREVGIEI
                     AAFLPTKFPIIGGKLNYRNHRKIVVIDGIIGYTGGINIGDEYLGKNDKFGYWRDTHIR
                     IKGISVYMLQMTFLIDWYYTTKEVLVTKNYFPSVGNVGESMIQVVASGPDSDWEDIHY
                     AYFSAICQARKNVYIETPYFIPDESLLKAIKSAALSGVDVRIIFPKIADHKIVNIASY
                     SYFEEILRAGGKVYLYNKGFIHSKVVIIDDKIASAGTANMDLRSFMLNFEVNAFIYDE
                     EVIRVMTDDFFEDLSHCEELNLEVFKNRNIIQKIKESVARLFSPIL"
     gene            12766..13050
                     /locus_tag="KRH23_001323"
     CDS             12766..13050
                     /locus_tag="KRH23_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012062101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_function: GO:0140662 - ATP-dependent protein folding
                     chaperone [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HHS5224608.1"
                     /translation="MKIRPLADRVVIKKVEAEEKTASGIVLPGAAKEQPQIAEVVEVG
                     PGGIVEGKEIKMELTVGDKVIFQKYSGTEVKIEGQEYTILRQSDVLAVIE"
     gene            13083..14711
                     /gene="groL"
                     /locus_tag="KRH23_001324"
     CDS             13083..14711
                     /gene="groL"
                     /locus_tag="KRH23_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729227.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0140662 - ATP-dependent protein folding
                     chaperone [Evidence IEA];
                     GO_process: GO:0042026 - protein refolding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HHS5224609.1"
                     /translation="MAKEIKFSEETRRALEAGVNKLADTVKVTLGPKGRNVILDKKFG
                     SPLITNDGVTIAKEIELEDRFENMGAQLVKEVATKTNDVAGDGTTTATVLAQAIIREG
                     LKNVTAGANPILLRKGIQKAVTVAVEELKNQSRIVETQEAISQVASISAGDEEVGKLI
                     AEAMEIVGKDGVITVEESQTMNTELDAVEGMQFDRGFVSAYMVTDVDKMEAVLNDPYI
                     LITDKKISNIQELLPVLEQIVQQGKKLLIIAEDVEGEALSTLVVNKLRGTFDVVAVKA
                     PGFGDRRKEMLQDIAILTGAQVISEELGYDLKEADLSMLGRASSVKVTKESTTIVDGS
                     GDKKAIEDRVTQIKHQVEQTTSDFDREKLMERLAKLAGGVAVVKVGAATEVELKERKL
                     RIEDALNATRAAVEEGIVAGGGTAFVSVIPAIGTLIESLEGEVKLGAQIVKKALEEPL
                     RQIAINAGLEGAVIVQNVVNSEAETGFDALNEKYVNMIEAGIVDPTKVSRSALQNAAS
                     IASTFLTTEAAVADLPEKEDAGMPGMGGGMPGMM"
     gene            14973..15713
                     /gene="larB"
                     /locus_tag="KRH23_001325"
     CDS             14973..15713
                     /gene="larB"
                     /locus_tag="KRH23_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nickel pincer cofactor biosynthesis protein
                     LarB"
                     /protein_id="HHS5224610.1"
                     /translation="MDLRKLLEEVKNENIDIDFALEKLKDLPYEDLGYANIDHHRELR
                     NGYPEVIYCEGKSDEHILGIIDKMNQKSSNILGTRCRKETFLKIKEIYNHAEYEEASK
                     ILKIQNHDIENIGKGKIVIATGGTSDIPVADEAYHTAKFLGNDVDRIYDVGVAGIHRL
                     LNKRHKIDSARVIVAVAGMEGALASVIGGLVDVPVIAVPTSVGYGANFGGLAALLAML
                     NSCASGISVVNIDNGFGAGYLASMINKL"
     gene            15848..16980
                     /gene="larC"
                     /locus_tag="KRH23_001326"
                     /pseudo
     CDS             15848..16980
                     /gene="larC"
                     /locus_tag="KRH23_001326"
                     /inference="COORDINATES: protein motif:HMM:NF014072.6"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nickel pincer cofactor biosynthesis protein
                     LarC"
     regulatory      17040..17141
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            17362..18897
                     /gene="guaA"
                     /locus_tag="KRH23_001327"
     CDS             17362..18897
                     /gene="guaA"
                     /locus_tag="KRH23_001327"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003922 - GMP synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016462 - pyrophosphatase activity
                     [Evidence IEA];
                     GO_process: GO:0006177 - GMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HHS5224611.1"
                     /translation="MKHELVLVIDFGGQYNQLIARRVRENNVYCEILPCTASIERIKE
                     KNPKGIIFTGGPNSAYLEDSPTISKEIFELGVPILGICYGIQIMSHVLGGVVRKGNKQ
                     EKEYGKTAITYGKSSLFEGITTNSVWMSHTDLIEKVPEGFTIVANTNDCPVAAMENVE
                     RNLYGVQFHPEVEHCLEGDKILTNFLYNICKVKGDWTTDSFIEDKIKELKEKIGDKKA
                     LCALSGGVDSSVAAVLIHKAIGDNLTCIFVDHGLLRKNEGNDVERIFREKFDINLIRV
                     NAEDRFLSKLKGVSEPEAKRKIIGEEFIRVFEEESNKLGKMDFLVQGTIYPDVIESGH
                     GNAATIKSHHNVGGIPEDVDFQEIVEPLRELFKDEVRKIGLELGIEEGLIFRHPFPGP
                     GLGIRVIGDVTKEKCDILREADAVYMDELRKAGLYREIWQAFATLPDVKTVGVMGDER
                     TYAYLVGLRAVTSSDGMTSDWYKMPYDVLERISNRIINEVDGVNRVVYDITSKPPGTI
                     EWE"
     gene            19475..20866
                     /locus_tag="KRH23_001328"
     CDS             19475..20866
                     /locus_tag="KRH23_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HHS5224612.1"
                     /translation="MRNKIIIGIAFSLVLLMSGCASKQTAEINVLATTDLHGVIPYEL
                     TSYVKEERKKDKNLTLVDAGDFFDSGEVSGSSMDSYFSARYKDIDNNTERYIETPISK
                     DMKEVGYDVAVLGNHEFISNNKFYLDNMISDFEKQKINILSANTYKKNGDSYTKPYII
                     KNINTPEGNVKLGILGLTIKEVGERKQWKDGKLVDSKSLELKDQEGYNGELYMNDLVE
                     DAKKWVGIMEKEKPDIIVAVAHTGEKPKKPKNPGNRIQDLAQQVDGIDAIVAGHNHVQ
                     IEQHDYKNKSGENVIVTEPGKHGECISKINFKLEKNNDKWNIVDKSSKLIKFEKNQES
                     DKFGEFISSINKVSKDKKEIRLSEVKTPEWDKIYVFKSGTSADDIYKTIGYKWRNISS
                     PKGDDMVQIVVMNNNKPVSYVYGEAEVMPINIKCDESEYKDNVVTIYPNKNDKFKIEK
                     GKQEYSINLKHIQ"
     gene            complement(21014..22030)
                     /locus_tag="KRH23_001329"
     CDS             complement(21014..22030)
                     /locus_tag="KRH23_001329"
                     /inference="COORDINATES: protein motif:HMM:NF015431.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HHS5224613.1"
                     /translation="MFFCFDSKYSSFFSLHIIQYTCCFVICKMIEFNGINQFYSCLVR
                     IFIMINIRYLEILEAIEQTGTFTGAAKKLHITQSAVSHAIAELEQQAETALFDRLPRG
                     VCLTRCGISLLEEARSILTACRNLDKRISRLEECTPINIVSSITIASFLLPPILSRLK
                     NSFPSLKVNVRVESANSAMDILKSGEADICFWEGIEPQGAFRTILLGSYKLCVACAPT
                     FPLSKQALSLRQLCTFPLLLREQGSAIRDTLDSVLSLSNQKAYPVWESVNSFALIKAA
                     QAGLGITILPENLLLDSLLHKKLRLIELDGIDMENKMLAILHKDKNITQPLKIILDNI
                     SNVL"
     gene            22009..22572
                     /locus_tag="KRH23_001330"
     CDS             22009..22572
                     /locus_tag="KRH23_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015109 - chromate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015703 - chromate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromate transporter"
                     /protein_id="HHS5224614.1"
                     /translation="MNQSRKTYFWLLIINLFISTFTFGGGYVVVPMIRRYFVNQKQFF
                     TEDDLMSMAAVAQSTPGAIAINLSALAGYRVAGTLGVVISCIAAIIPPLVILGLVSAF
                     YTTFISNAIVTAVLKGMQAGVAALIVDLIIDMCSMILKQRSLFLSAMIPIAFFANFVM
                     SINVIFILSVCCFVCVMQAFYKKRENK"
     gene            22569..23135
                     /locus_tag="KRH23_001331"
     CDS             22569..23135
                     /locus_tag="KRH23_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015109 - chromate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015703 - chromate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromate transporter"
                     /protein_id="HHS5224615.1"
                     /translation="MNTIWNLFFIFLKIGLFSIGGGYAIIPLIQEKVVNQTGWISEKM
                     FTDIITISQMTPGPLAVNTSTFVGLQIGGFWGAVSATLGCVLCGVVISLFLYNFFQKH
                     QNSTYIFEILNGLKSASLGLIISAAATIIILALFGTNKVYFNSIFEMLNWTALIIFFV
                     TLLIVRKWKINPIVIIIISGILGIFFYL"
     gene            complement(23264..23500)
                     /locus_tag="KRH23_001332"
     CDS             complement(23264..23500)
                     /locus_tag="KRH23_001332"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224616.1"
                     /translation="MLECFIAKDSKIKDGVNIPTLVFKTLHDRYFKTQYFDSYYNSLK
                     CKKKLVEINNVHNSYYIDSEKFCQEAYDWFIENQ"
     gene            complement(23788..27216)
                     /gene="uvrA"
                     /locus_tag="KRH23_001333"
     CDS             complement(23788..27216)
                     /gene="uvrA"
                     /locus_tag="KRH23_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HHS5224617.1"
                     /translation="MKINNYKNQSIITNPKKFENKYQDLPKTPIELLKVVQSLVIHGD
                     QGKLYGISFNKQQSDEELLRTIPQMLKRIFEINSNPLTIPRNPKQRLVGMCRDYSLLL
                     VSLLRYRGFEARMRAGFANYFESELTYEDHWLVEYYDTLTKRWIRIDAQIDDIQKNYF
                     QINFDTHDVGKTDGFLTGSEAWIRCRQGHAHPDDFGYNKNWKGWHSVKGNLLHDFNNM
                     IGLELLPWDLWTELSSKKYNQLTRAEKNLLDEMAEILSSGNIKIEDLNLLIEKLPEDY
                     LKSIFSQLKILGISEIKELGNPLELEKKFKFTKSINKSIKNSLCHNKSSIYLKGGRQN
                     NLKDVEVTIPKNQITVITGVSGSGKSSLAFDTIYEEGKRRYFENLSNGAKLSEQLQKP
                     EFDLLQGLTPTIAIEQKKGSQNPRSTVGTLTSIWDYLRMLFVSIGKSYCPYCKIPLEK
                     KNNTKNYCPHCQTIFSKINTSTFNANSHTGACHDCNGLGFTYQVNPQLIVKDPTISIL
                     DGATYYFGKLRGKKPNGNWMVGELYAIAKDKNIDLDIPWNELPRDFIDAILYGTDDKI
                     YEFSFESKGRESKIRRPASGAINHIQRLFRESSSENNTLHQYMNKIPCNTCGGELLCI
                     EARFTTIKGYRFPELTKMTIEQLWNWLCELPNQLQKNELSLVNDILTELKIRVSYLLK
                     VGLSYISTDRTAPTLSGGELQRVRLSSQLGSELVGLTYILDEPSIGLHPRDHNLIIKM
                     IEELRDKGNTVIVVEHDKDTILSADYIIDVGPSAGTKGGFIIAEGTTQEIIKNPNSIT
                     GKYLSTYNKTGSQNKTIPSKWLSLKGCHANNLKNIDVEIPLNCMCSITGVSGSGKSSL
                     VFHSLLPALEEKLKQKSIPDKNYTEFTGFDAIDDFILMDQTPIGKSSRSTPATYINIF
                     DEIRSLFAETPQAKQKLLDESYFSFNSKKGQCPNCQGLGKTKIILQYMADQWVTCSEC
                     QGKRYQKEILSIQYKGKTIADILDMEVAEAKTFFSDCSDIYRKLSLLDEVGLGYLKLG
                     QNTLGLSGGESQRIKLAKELGTKTKKRMLYILDEPTTGLHFKDIENLLITFRKLVNEQ
                     HSLLIIEHNTEVIRASDWIIDIGPDSGINGGEIVASGTPDEIKINPNSITGHFI"
     gene            27535..29769
                     /locus_tag="KRH23_001334"
     CDS             27535..29769
                     /locus_tag="KRH23_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HHS5224618.1"
                     /translation="MKLSRYKKNSLVLSIILCSLIISILVITVFNTVKLHNISNKQSK
                     NYLNDVSTQIVMNVDSKIKFILSDLRIMADFIKQYEGDSRYEYLSKRKTSYKYYDVGI
                     IDLEGKAEFLSGKKFDLKNTASYKKGIEGKEYSEVIESMGFVLYSVPIFNDNHEVSSI
                     LIGVSNKESMNEILNIDNFNGEGTIEIINSKGKPLFIGKNTELIKDLSHKYKDSADEL
                     WAQKMLNDFKNDKSGNITITSSKGVQCLLTYHPITRGLNDWHFLLIVPEDAVLGELNK
                     LNSFTITMTFIITCIIGIITLILYIIRRKYVNQIENIAYLDSITNGINSTKFSMLVKP
                     LISESPDSTYMMIAMNIKDFKLINDCFGSEKGNMTLKHLYNVLYKNIDENEEFVCRHD
                     ADLFYLLIKNRPVLEALELLYKIEDDTNYFNKNRENPYFLRLSVGIYTIENHNEDLIT
                     IQDHANTARKSFNKTHQSDFSFYSDIERKRLISEKEISNLMEKALENKEFFMCLQPKI
                     DIKSGKISGAESLVRWKNSEKGIIYPSDFIPLFEKSGFICKLDLYILEETCKLISKWI
                     KEGKEVLRISVNVSRQHLNDKLFLEKYKHICNKYNVPTCLIDLELTESIFLENPEAID
                     IIEDIHSNGFKCSIDDFGFGYSSLGILKDFKVDIIKLDRSFFVSKNNIDRGKVVIKSI
                     IELSKRLGMKVTAEGIEELEQVEFLKNVGCDYIQGYVFSKPLLISDFENFAYENNKIK
                     NIHY"
     gene            30025..32055
                     /locus_tag="KRH23_001335"
     CDS             30025..32055
                     /locus_tag="KRH23_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HHS5224619.1"
                     /translation="MISGRMLLIMNFLKGKNKTSYKDISKQLSIEERKVRYDINNLNI
                     VLRSLNKSVIQKMNKGVLIIPDDFQVVCINNNEYVFSLTERVSIMKIISMFKIDNLNL
                     EKLSKEFQVSRSSIKNDLNVLSSELERNQITITYDKAFKISGEEDIIYKQRLNILKSY
                     SYLFGKEKSDLSVFEKYLVNVIEKIFKGIYLIDIYNWSMNLLLQMGWTLNDESFTWYV
                     SNIFLFTWYIHSDEKHPLESASLSEPCFENKFDQEFETIIQKKLTKEQIFLLKSFVFF
                     TNKYASLNEDMDLISTEIIVQDLIYNMSEILEISFKEDMILYKGLLNHIAPLIERIKQ
                     NIQIYEELLHVIPDKYQYVLEATKVSIQKNRVLSQIKNENETILLAIHFLGSIHRNER
                     NNYKNILLVCGFGYGVIAMLKDSLVNDYQINIVESIPSYKLQDYKDWESIDFIITTSK
                     IVIDLPKTIIEINPFLQEEDYLKFEEKGIKRKNVLTNYMSIKKRLDFLEEDAQKRVLS
                     IICQELGYSDERILFRQLNLSDLIGIDTIRIIDGDMKWEDAVKFSSNILANCDFVSAQ
                     YAENIIDILKNVGFYAVKDNEFALLHGNDSSLVKVSSISLLICKEAVSFGDKKVKIIF
                     CLASRDKKEQIPAIINLTKMVYKTNFIAMLESAKTKEEAEVLIHKYEKEVTV"
     gene            32052..32504
                     /locus_tag="KRH23_001336"
     CDS             32052..32504
                     /locus_tag="KRH23_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HHS5224620.1"
                     /translation="MNKLVNVKCSFKIHVNSKEEAIISLVDVVSKEGYLIDKNQFLKD
                     VLKREETLSTYIGHGIGLPHSQSVGVKNSCITIGKLDTPIEWTEEGEKVDLIFLISVT
                     KDNENNLHLKILSKLARLLMHESFRNQIRCSDEQTVYNLIKEKIEEED"
     gene            32506..33561
                     /locus_tag="KRH23_001337"
     CDS             32506..33561
                     /locus_tag="KRH23_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit EIIC"
                     /protein_id="HHS5224621.1"
                     /translation="MRILKFLQKHLMTATSYMIPFVVAGGILFALSVTLSGQAAVPET
                     GWLAKLNQIGAAGLALFIPILGGYIAFSMADKPGLAPGMIGAYLAKEVNAGFIGGIIA
                     GFIAGFVVLQLKKIKLAPTMRTLGSIFIYPLIGTLITGGIIVFLIGEPIASFMTWMTN
                     WLNGMSGVSKIPLGGILGGMIASDMGGPINKVAATFAQTQVDTLPYLMGGVGVAICIP
                     PIGLGLATLLFPKKFSKEERDSGKASLLMGCVGITEGAIPFATSDPVRVIPCIMAGSI
                     VGNIMAFLLGCLNHAPWGGLIVLPVVDNRLGYIASVLTGAVVVAVLMKLVKKDVKEDE
                     EIEEDLDESIELIFEEL"
     gene            33628..33936
                     /locus_tag="KRH23_001338"
     CDS             33628..33936
                     /locus_tag="KRH23_001338"
                     /EC_number="2.7.1.202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022877 -
                     protein-N(PI)-phosphohistidine-fructose phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose-like transporter subunit IIB"
                     /protein_id="HHS5224622.1"
                     /translation="MKIVAVTSCPSGVAHTYMSAESLELSAKKFSIEIKVETQGSSGI
                     DNELSLKDIDEATCVILTNDVEIRNIERFKGKKVVRMSVSEIIKKSDALIKKIKDTFQ
                     "
     gene            34040..35305
                     /locus_tag="KRH23_001339"
     CDS             34040..35305
                     /locus_tag="KRH23_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class II D-tagatose-bisphosphate aldolase
                     non-catalytic subunit"
                     /protein_id="HHS5224623.1"
                     /translation="MKKLPIKTVVQRLLNLQEEGKSATLLGIGPMSPNLLQASFELAK
                     DDDFPLMFIASRNQVDADELGGGYVNGWNQETFTKDIKKVADKVGFDGLYYLCRDHGG
                     PWQRDKERNDHLPVDEAMELGKKSYLADIEAGFDLLMIDPTKDPFEIGKVIPLDVVLE
                     RTVELIEYCENERKRLNLPDIGYEVGTEETNGGLTSTETYETFITRLKVELDNRGLPM
                     PTFIVGQTGTLTRKTEQVGTFNFRNAYDLAQMAKKYGVGLKEHNGDYLDDVTLLEHIP
                     SQIIATNVAPQYGTEETRAYLKLAEVECKLEKEGLVDKTSNIRHVLLVNAIECGRWRK
                     WVVGEQKNLTTEEIFKNEVLSNEILDIAGHYTFNNDDVKKEIEVLYDNLSKNNIDGQR
                     FVVDYIKRPLRDYAECYNLKGVTTRILNK"
     gene            35393..36109
                     /locus_tag="KRH23_001340"
     CDS             35393..36109
                     /locus_tag="KRH23_001340"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HHS5224624.1"
                     /translation="MINLIFDVDDTLYNQLTPFYTAYNKVFSSIKDISIEDLYMSSRK
                     YSDEVFHMTENGEMPIKEMHIYRIMKAFEELGNSITEKDAQSFQDEYIYQQSQITLIP
                     EVERILNFSKERNINLGIITNGPSNHQRMKLKQLNIENWVDKSNIFISSEVGFSKPDT
                     NIFRVAENVMNLDRENTYYVGDSYRNDVLGAKKAGWKSIWLNHRGHEVEELFYKPDFV
                     ILEHKDLISLFIRICSYKNM"
     gene            complement(36304..36597)
                     /locus_tag="KRH23_001341"
     CDS             complement(36304..36597)
                     /locus_tag="KRH23_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat protein"
                     /protein_id="HHS5224625.1"
                     /translation="MRNMIENLIKNNTYIDDKVIMLSMLSSAKASANMYLNSALTSST
                     PELRAIYSASLTQMVEGHTALTELSINKGWVKPYDKPIQQLTCSYKESQNVID"
     gene            complement(36603..36818)
                     /locus_tag="KRH23_001342"
     CDS             complement(36603..36818)
                     /locus_tag="KRH23_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224626.1"
                     /translation="MRILSETEKISLAAIIKMESDGLLMQRAINMLISDEDLKRQSES
                     SILATEGRIKAIQQFIVENEILISEEV"
     gene            37265..37663
                     /gene="tnpA"
                     /locus_tag="KRH23_001343"
     CDS             37265..37663
                     /gene="tnpA"
                     /locus_tag="KRH23_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011100796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HHS5224627.1"
                     /translation="MYKSNKNIVYDCKYHIVFCPKYRKPVLVGEVEKMLKEILPYKAD
                     ELGAEIIEMETDKEHVHLLISCDPQYGIHKVVKGLKGFSSRVLRENFPHLKSSMPSMW
                     TNSYFVGTVGSVSLEVVKQYIENQQVRTKK"
     gene            37660..38823
                     /locus_tag="KRH23_001344"
     CDS             37660..38823
                     /locus_tag="KRH23_001344"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0032196 - transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-guided endonuclease InsQ/TnpB family
                     protein"
                     /protein_id="HHS5224628.1"
                     /translation="MIKTHRVKLNLTRTQFELVREKQMESANCWNYIVNLSKEYYFEH
                     KQWIKKNDIQKLIKGKYNLHSQTIQAISDKFDANRKTISELRKKGNTKAKYPYKTKKF
                     YIIPFKASAINRNAKGNLKLSMSKGRYLELDFNVENIKTAEIVWRNGYYLYYTFDNEL
                     NGVVAKGTNTVGVDLGEIHSIASVTNKGVGLILSNREGRSIKQFRNKMYAYISKRLSK
                     CKKGSRQSKKLWRLKNKIRSKTDNQLMNLYHQTTRKFIDFCVEQKVCEIVLGDIKGVE
                     KDTKKKKRLNRVNRQKISQMEYGRIKDYIKYKAKEQGIEVKLVKENYTSQTCPKCSKK
                     HKPTGRTYSCTCGYETHRDIVGAWNILNKKHKYGLVDFRINHKQPINLKVSTV"
     gene            complement(39207..39719)
                     /locus_tag="KRH23_001345"
     CDS             complement(39207..39719)
                     /locus_tag="KRH23_001345"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HHS5224629.1"
                     /translation="MLEVIKNRRSIRTYIDKNIEEDKITEILKSAMQAPSSKNAQPWE
                     FIIVDDKELLKELSKSQHRAKHIEFAPLCIVVLGNRDKFLKPGKWIQDLGACTQNLLL
                     EVTNQGLAACWAGVFPKNKVVNKVRQTLDLPLKLVPYALISIGYSEEKNEFIDRFDEN
                     KIHRNVYKNR"
     gene            40169..40645
                     /gene="purE"
                     /locus_tag="KRH23_001346"
     CDS             40169..40645
                     /gene="purE"
                     /locus_tag="KRH23_001346"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009320 - phosphoribosylaminoimidazole
                     carboxylase complex [Evidence IEA];
                     GO_function: GO:0004638 - phosphoribosylaminoimidazole
                     carboxylase activity [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HHS5224630.1"
                     /translation="MKVAVVMGSKSDYPKLEEGIKLLEKYGIEVVARALSAHRTPEQL
                     SIFLKEIEDDIDVIIAAAGKAAHLPGVIASQTLIPVIGLPIKSSTMDGLDSLLSIVQM
                     PKGIPVATVTIDLGLNAALLALQIMTLKYPKLKEDLKSYREEMAQKVLEDDKNLRG"
     gene            40651..41349
                     /gene="purC"
                     /locus_tag="KRH23_001347"
     CDS             40651..41349
                     /gene="purC"
                     /locus_tag="KRH23_001347"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004639 -
                     phosphoribosylaminoimidazolesuccinocarboxamide synthase
                     activity [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HHS5224631.1"
                     /translation="MLLYEGKAKQVYSTDNENEYVVYYKDDATAFNGEKKAEISSKGI
                     LNNKISTIIFEMLKENNINTHFIKSLSDREMLVKKVEILPLEVIVRNIAAGSICKRVG
                     LEEGVVFDEPIFEISYKNDAYGDPMLNDDYAVAMKLATREELKFLREETLKINELLKA
                     FFLKLNLKLVDFKIEFGKDSEGNIILADEVSPDTCRLWDVNTNEKLDKDRFRKDLGDL
                     VEGYTEVLSRMNNK"
     gene            41361..42728
                     /gene="purF"
                     /locus_tag="KRH23_001348"
     CDS             41361..42728
                     /gene="purF"
                     /locus_tag="KRH23_001348"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004044 - amidophosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009113 - purine nucleobase biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HHS5224632.1"
                     /translation="MCGVLGIYSNKDVTKELYYSLYSMQHRGQESCGLALLDDGEIKY
                     KKDMGLVGDVFKENELSKLKGNIGIGHVRYSTAGGSHVSNCQPLVGSCRKRQLAIAHN
                     GNLVNANYLKDMLEEDGYMFQTNSDTEVILYILARYYKGDIVESLKVTMDYIKGAYAL
                     VIMSQEELVAVRDPHGFRPLVLGKKGDEYIFASENCAIDILGGEVIRDVEPGEIIVVK
                     DGELKSYFYSENYKPVKKSCIFEHIYFARNDATIDNVNAYEFRIKCGERLAQNETVKA
                     DMVVPVPDSGWPGAIGYANASGLKISEGLVKNRYVGRTFIKPTQEEREIAVKIKLNPL
                     STIIKGKSIILVDDSIVRGTTSKQLVKSLREAGAKEIHLRITSPPVAYSCYYGIDTPN
                     RSKLIASSNNVEEMREYIGCDSLKFLDIEGMLDATEHKSTFCKACFDGEYPVKKIDKE
                     ELLSC"
     gene            42722..43798
                     /gene="purM"
                     /locus_tag="KRH23_001349"
     CDS             42722..43798
                     /gene="purM"
                     /locus_tag="KRH23_001349"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004641 -
                     phosphoribosylformylglycinamidine cyclo-ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HHS5224633.1"
                     /translation="MLTYKESGVDIDEGNRAVDLIKGKIKGTYDGNVVGDLGNFSGLY
                     SLKDFVGMKEPVLLASTDGVGTKLKIAQMMDKHDTVGIDLVAMCVNDLICQGAKPLFF
                     LDYIALGKLVPEHIEKIVGGIADGCKMSGCALIGGETAEMPGMYGEDDYDLAGFSVGI
                     ADKEKIVSGNNVKSGDVLVGISSSGVHSNGFSFIRKIFLETYNYKMEQYVEELGMTVG
                     EALLTPTKIYVKLALDVLAKHDIKAIAHITGGGLIENITRVIPKGLGLDINKKSWEKP
                     PIFKMIEGFNAVDERELHKSFNMGIGLVLIVDKENADDVVNFINNRENDNAAYVDKKY
                     SELLEDKAYIIGEVVDSHEGVELC"
     gene            43792..44385
                     /gene="purN"
                     /locus_tag="KRH23_001350"
     CDS             43792..44385
                     /gene="purN"
                     /locus_tag="KRH23_001350"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004644 - phosphoribosylglycinamide
                     formyltransferase activity [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HHS5224634.1"
                     /translation="MLNIGVLISGGGTNLQAVIDGTESGEIKGQVKVVISSKQGAYGL
                     ERAKNHNIKAICETDEDKIIEILKENKIDLVVLAGYLKIISPKLVNEFRNKMINIHPS
                     LIPSFCGAGFYGEKVHQGVIDYGAKVTGATVHFVDEGADTGPIIMQDVVKVNQDDDAK
                     TLAKRVLEVEHRILKESISLFCENKLKLQGRRVFINE"
     gene            44378..45910
                     /gene="purH"
                     /locus_tag="KRH23_001351"
     CDS             44378..45910
                     /gene="purH"
                     /locus_tag="KRH23_001351"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0003937 - IMP cyclohydrolase activity
                     [Evidence IEA];
                     GO_function: GO:0004643 -
                     phosphoribosylaminoimidazolecarboxamide formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HHS5224635.1"
                     /translation="MSKRALISVTDKTGVVEFAKELNKLDYEIISTGNTFKTLKENGV
                     NVMQVEDVTNFPEILDGRVKTLNPYIHGGILYKRDKESHVETVNEHKIHSIDLVAVNL
                     YDFEGTLKAGKSHDEIIENIDIGGPSMIRSAAKNYKDVIVVVDIKDYDSIIEKLKTDT
                     MTLEDRKKLSYKAFSTTGRYDALISSYFAGEVGDTYPDILNLTFQKEQTLRYGENPHQ
                     NGFLYSQSNAKNPILNYEQLGGKELSFNNLNDLHGCLEVMREFKDSEEVVSVAIKHAN
                     SCGVGLGKDAFEAYTKCYEADKVSIFGGIVGITSTIDKATAEKLNEIFLEIVVAYDFE
                     PEALEILKQKKNLRILKLAKIENSLQPYEMKYLDGKLLIQDRNNILAEKSENVTKEKP
                     TDAQLKDMEFGMRVVKNMKSNAIAVVKNGQTLALGCGQTSRIWALKNALENNKDKDFT
                     GAVLASDAFFPFDDCVTLAHEYGISAVVQPGGSIKDKDSIEACDKYDMVMVFTGIRHF
                     KH"
     gene            45921..47171
                     /gene="purD"
                     /locus_tag="KRH23_001352"
     CDS             45921..47171
                     /gene="purD"
                     /locus_tag="KRH23_001352"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004637 - phosphoribosylamine-glycine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0009113 - purine nucleobase biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HHS5224636.1"
                     /translation="MKILVVGGGGREHAICWKLSKEKNVEKIYCAPGNAGIANVAECV
                     NIGDTNIEELLKFAKENEIGLTIVGPEVPLVMGIVDEFEKEGLRVFGPNKKCAQLEGS
                     KAFSKEFMIKHNIPTAKYKEYTNLEEAISEIDSFGYPVVIKADGLAAGKGVVIPENRE
                     DAIATLKEMMSDKKFGAAGDKIVIEEFLKGIETSILAFVDNDTIVPMASAKDHKKVNN
                     YEQGPNTGGMGTFSPSEIYTEELANKVKETVLEKTLEGFKKDGLNFKGILFVGLMITE
                     DGEKVLEYNVRFGDPETQSVLFRLETDLHEIMEAILDNKLKDIEINYSDDEAVCVMLT
                     SGGYPDSYEKGKIITGLENLDDDIVVFHSGTKMFDGNLVTNGGRVIGITAKSTTVKDA
                     AEKVYENIKKINFEGMHYRTDIGR"
     gene            47196..51002
                     /locus_tag="KRH23_001353"
     CDS             47196..51002
                     /locus_tag="KRH23_001353"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004642 -
                     phosphoribosylformylglycinamidine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HHS5224637.1"
                     /translation="MLNTENKDSMVRRVLVEKREGFDLEAKALKKDLVESLHIDNIEN
                     LRILNRYDVEGISEEVYENAAKTIFSEPNLDVVYYEEIPKLNDERVFAIEFLPGQYDQ
                     RGDWAAQCVQIVNQGIRPAINTAKVYILSGKITDEEFSKIKDYCINPVDSREASLEKP
                     ETLKMETEIPTTVEVLDGFIDLDENGLRTFVSEKGLAMTLGDLQHVQKYFKDTEKRNP
                     TITEIKVLDTYWSDHCRHTTFMTEIENVKIEDGKFNDIVKEAYQMYLNSRDNVYVNRH
                     KDICLMDIATVAVKELKKNGKLNDLDESEEINACSINVDVEVDGKMEKYLVMFKNETH
                     NHPTEIEPFGGAATCLGGAIRDPLSGRSYVYQAMRVTGSADPRTTLEDTLPGKLMQRK
                     ITTEAAHGYSSYGNQIGLTTGQVAEVYDENFVAKRMEIGAVIAAAPKENVVRERPEAG
                     DVIVLLGGKTGRDGCGGATGSSKEHSEESILTCSAEVQKGDAPNERKIQRFFRNKEVA
                     QMIKRCNDFGAGGVCVAIGEIADSLDINLDLVPKKYDGLDGTELAISESQERMAVAIK
                     KENKDKFIQLAVEENLEATHVATVTDTGYLRMFWNGKAIVDINREFLDTNGVKQTTDV
                     HVTKVDEENTFFSSNEIVKDVKCASMKDKFTKVLSDLNVCSQKGLVEMFDNTIGGNTV
                     LMPFGGKYQATPTQGMVAKIPVLGGETNTSTIMTYGYNPKVGKWSPFHGALYAVVESV
                     CKLVAIGGNYSTTRLTFQEYFEKLGNNPEKWGKPFSALLGAFYAQSKFEIPAIGGKDS
                     MSGTFKDIEVPPTLVSFAVDTVDAKKVVSPEFKKADSKVVMLCVNKAENDVVDFEELK
                     RNLDKVRELIHGNKVLSTYALGFAGVGEAISKMAFGNKIGFKFSEEAEKAFTDDKLFE
                     ASYGNIVLELANDDLSMLEGYNYVVLGSTVKEASIFIKGEELALDELYKAHCSTLEPI
                     FPTKTEEVKSKIETISYISQGEAKKSSLSIATPRVFIPAFPGTNCEYDSARAFERAGA
                     NASIRVFKNLTYKDIEDSIDTIVNEIKSSQIIMLPGGFSAGDEPDGSGKFIATVFRNP
                     RVQEAINEFLTQKDGLMLGICNGFQVLIKLGLVPYGEIRVPSESAPTLTYNNIGRHQA
                     KIARTRISSNKSPWLAQTNVGDIHNIAISHGEGKFVASEDVMRELIANGQVATQYVDF
                     NNEATYDIEFNPNGSFYAVEGITSADGRVFGKMGHSERIGEEVYKNIIGEKDQKIFES
                     GVKYFR"
     gene            51208..52080
                     /gene="rfbD"
                     /locus_tag="KRH23_001354"
     CDS             51208..52080
                     /gene="rfbD"
                     /locus_tag="KRH23_001354"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008831 - dTDP-4-dehydrorhamnose reductase
                     activity [Evidence IEA];
                     GO_process: GO:0009243 - O antigen biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HHS5224638.1"
                     /translation="MKILITGSNGQLGKELVNQLEAINQSINQPKYVILATTRSDLDI
                     SNQTNVDNFILHNKPDVVVNCAAYTKVDACEDNIEIAYKINALGVRNLAIASEKVNAK
                     LIHISTDYVFNGFSKYPYREDNKTEPNSVYGKSKLMGEKFVEQFSHKYFILRTAWLYG
                     NGNNFVKTMIKLSLENTEVNVVNDQFGTPTSTVDLAKIIIKIMETEHYGVYHATCEGE
                     CSWYDFAKKIFKLKNIDIKVNPIKSNEFKCKAPRPLYSVLDNFMLKLIGLNSFRKWEE
                     SIEEYLERYDINEK"
     gene            52189..53058
                     /gene="rfbA"
                     /locus_tag="KRH23_001355"
     CDS             52189..53058
                     /gene="rfbA"
                     /locus_tag="KRH23_001355"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008879 - glucose-1-phosphate
                     thymidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HHS5224639.1"
                     /translation="MKGIILAGGSGTRLYPITKCISKQTLPIYDKPMIYYPMSVLMLA
                     GIQDILIISTPRDIKAFEELFGDGSSLGLNITYAIQEKANGIAEAFIIGEEFIGNDRV
                     SLVLGDNIFYGYGFSERLENAVKRKGATIFGYHVSNPNSFGVVEFDKDFNVLSIEEKP
                     TVPKSNYAIPGLYFYDNDVVEIAKLVEPSDRGELEITSINSEYLKRGKLKVELLGRGM
                     AWLDTGTHKGLLDASNYVEVVQTRQGLYIACLEEIAYTKGYISREQLMKLAKPLIKTE
                     YGQYLLKLASEDM"
     gene            53107..53664
                     /gene="rfbC"
                     /locus_tag="KRH23_001356"
     CDS             53107..53664
                     /gene="rfbC"
                     /locus_tag="KRH23_001356"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008830 - dTDP-4-dehydrorhamnose
                     3,5-epimerase activity [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HHS5224640.1"
                     /translation="MGKINVIKTKIEGLYIVEPNVFYDERGYFMESYNKKDFIEQGLD
                     MCFIQDNESSSRKGVLRGMHFQVKYPQGKLVRVTEGEVFDVAVDLRKDSQTFGKWEGV
                     ILSDKNKKQFYIPEGFAHGFLVLSEKAVFSYKCTNYYYPEFENGFIWNDKQISIEWPL
                     KGIEEIFLSEKDKKQKSFKDICTRR"
     gene            53702..54685
                     /gene="rfbB"
                     /locus_tag="KRH23_001357"
     CDS             53702..54685
                     /gene="rfbB"
                     /locus_tag="KRH23_001357"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008460 - dTDP-glucose 4,6-dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009225 - nucleotide-sugar metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HHS5224641.1"
                     /translation="MKKILITGGAGFIGSNFIHYMLNKYVDYFIVNLDLLTYAGNLET
                     LIEIQDNSNYKFVKGDISNREQVYKLFEEERFDIVVNFAAESHVDRSVENPDLFIKTN
                     IIGTQVLLDASIKYGVKRYHQISTDEVYGDLPIDRKDLFFTEQSSINPSSPYSASKAS
                     ADLLVSSYYRTYGLLTTISRCSNNYGPYHFPEKLIPLMILNALENKQLPVYGNGENVR
                     DWLHVYDHCTAIDLIIHKGNIGEIYNIGGHNERSNLEVVKMILNLLGKSEELISYVND
                     RPGHDLRYAIDATKIENELGWKAKYDFDLGIKETVKWYIENESWWKAVLSV"
     gene            54715..55383
                     /locus_tag="KRH23_001358"
     CDS             54715..55383
                     /locus_tag="KRH23_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008933 - peptidoglycan lytic
                     transglycosylase activity [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0000270 - peptidoglycan metabolic process
                     [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing
                     protein"
                     /protein_id="HHS5224642.1"
                     /translation="MNEISSLINILALTQLSGSNTTNQCNCTYNNSSGFDMIMMTLLK
                     ALSQNNQHTSNSYNLLSNSENLFNELDNVVNNTTSRFIDVDTKDKNVKLRIENAVDQA
                     SKKYNVDSNLIKAIIKVESDFNPNTVSSAGAKGLMQLMPENCRDLGVTDPFNIEQNID
                     AGTRHIKEYIDMFGGSIEMGLMAYNGGPGRMKSRGVESISDLYKMPKETQNYIPKVMK
                     YYRG"
     gene            55392..55820
                     /locus_tag="KRH23_001359"
     CDS             55392..55820
                     /locus_tag="KRH23_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaaR family protein"
                     /protein_id="HHS5224643.1"
                     /translation="MGINIDKLNISPSINMEVKKLKESNKFSDKLNSLKQSSSLEDIK
                     RNLESVKKAGERLVLTQNYGDISIYKNAVKEYLKSVVDNMYSLDKNSSFWEHQYYKNV
                     KIVDSKLEDMTSKLISEEKENIDIVSTVDMIQGLLIDMYR"
     gene            55844..56158
                     /locus_tag="KRH23_001360"
     CDS             55844..56158
                     /locus_tag="KRH23_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliM/FliN family flagellar motor switch protein"
                     /protein_id="HHS5224644.1"
                     /translation="MNSKKEDIYELNFGQLIEEKSGVIEENQNVFNAKVNVAVSIGNT
                     TETIKNILDLKEGSIIKLSKNVDEKLDIYANDRLFAYGESIITNERLSVRLSKIEDPD
                     VN"
     gene            56310..56585
                     /gene="flgM"
                     /locus_tag="KRH23_001361"
     CDS             56310..56585
                     /gene="flgM"
                     /locus_tag="KRH23_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis anti-sigma factor FlgM"
                     /protein_id="HHS5224645.1"
                     /translation="MDIKNVSSNIVVNNYLKNTSGIKKVEEVKKINKTDKIELSKFAK
                     EMASVSNMSDENIRNKKVDEIKNALENGTYKIKPKEIAKKMIEDMRG"
     gene            56590..57006
                     /locus_tag="KRH23_001362"
     CDS             56590..57006
                     /locus_tag="KRH23_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein FlgN"
                     /protein_id="HHS5224646.1"
                     /translation="MITDLKVIIYEEKNIISKMMELLKEQFDYIVEKDLENLNMLNPK
                     LEDISRELASIEIKRRQLFGDDISMSEVVENSNDGYLKEIYTDLKHILALAKNQQESN
                     DSLIKKELIFTKKMINFIKPADKKTTTYNSYGNIRK"
     gene            57024..58334
                     /gene="flgK"
                     /locus_tag="KRH23_001363"
     CDS             57024..58334
                     /gene="flgK"
                     /locus_tag="KRH23_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009424 - bacterial-type flagellum hook
                     [Evidence IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0044780 - bacterial-type flagellum assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-associated protein FlgK"
                     /protein_id="HHS5224647.1"
                     /translation="MAGLFSILNTANSGMNAHQKAIQTISHNISNLDTDGYSRQRTEF
                     ATNSPMYMPSLSNSIARGQLGTGVHVTDVTRARNSFYDYQFRAEAHKYGKTVSKYDYY
                     NTIETILNEPSDYGISAGIDDFFKGWESLSKDINSDSKKSLVVENASNLATLISESYK
                     KLDKLKEDIDSNIDTEIKQINDMLKSLEDLNKSIDIISGSGSTPNDLLDERDRILDNL
                     SFKLDFENSDVKNMLADGKLELNELKNPDGTWKTGISGTLQGLFEMHGKIDTYKSDLK
                     DVSDGLAKQINDVYNTSAGITVTDFFITSNVDGEDIIKINPAIKSNPNELKLTADEAS
                     KIAKLKDEKIDIGVAGGKVSTISDHYKAFAESIGLDSQKVNQDEANQRKIINNIDNSR
                     MSVSGVSLDEEMTELIKIQRSYQASAKVMSTAVQLLDVVINGII"
     gene            58353..59285
                     /gene="flgL"
                     /locus_tag="KRH23_001364"
     CDS             58353..59285
                     /gene="flgL"
                     /locus_tag="KRH23_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009424 - bacterial-type flagellum hook
                     [Evidence IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0001539 - cilium or flagellum-dependent
                     cell motility [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-associated protein FlgL"
                     /protein_id="HHS5224648.1"
                     /translation="MRVSTGMMSSSYLNSLQDNLQRLDKVNRQVNTTKEINKLSDNPY
                     KAIKILNSKSEIKTMETYVENCKDTGNWLETTDTALDQLGKLLSDIKKTLVASGDGAY
                     SDDELKTLSNETNEKMKEIANALNATHEGKYIFSGSNTGVPPVECIDNADGSVSLKFN
                     SSLNLNKLNDSLSMDIAQGISVDYNVKLSSLGFDPTKTDPFEELNNISKKLANPDADA
                     IKELTTTCLGDMEQLIENTVNVRSIYGTKANTVEAMKEKNDDSLIQLKDILSQNEEID
                     YGEKLVQLKAAELTYQASLQTGGKLFNVSILDYI"
     gene            59301..59693
                     /gene="fliW"
                     /locus_tag="KRH23_001365"
     CDS             59301..59693
                     /gene="fliW"
                     /locus_tag="KRH23_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006417 - regulation of translation
                     [Evidence IEA];
                     GO_process: GO:0044780 - bacterial-type flagellum assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar assembly protein FliW"
                     /protein_id="HHS5224649.1"
                     /translation="MMKVTLKKGILGFENLKEYELLDIEDNDYLKEFNSTEEEGIGFV
                     VVSPFEIINEYEIVLNQETIEKLEVKSPKDVVLFNIITLGQTFEESTVNMKAPIVINI
                     KTNFGMQIILQDDKYSIRHPLLRGDSGC"
     gene            59687..59899
                     /gene="csrA"
                     /locus_tag="KRH23_001366"
     CDS             59687..59899
                     /gene="csrA"
                     /locus_tag="KRH23_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006109 - regulation of carbohydrate
                     metabolic process [Evidence IEA];
                     GO_process: GO:0006402 - mRNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbon storage regulator CsrA"
                     /protein_id="HHS5224650.1"
                     /translation="MLVISRKKDEAVLIGESIEVKIVGVDGNNVKLAISAPNNISILR
                     KEIYEKVKSENIKATNKNIKILKSLK"
     gene            59921..60316
                     /gene="fliS"
                     /locus_tag="KRH23_001367"
     CDS             59921..60316
                     /gene="fliS"
                     /locus_tag="KRH23_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0044780 - bacterial-type flagellum assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar export chaperone FliS"
                     /protein_id="HHS5224651.1"
                     /translation="MYGENPYNSYKQNAVFMASKEQLLLMLVDGAVKYTKIARAAILD
                     KNTQKAHRELVRVQDIFTELMVTLDQNAGQWAKDMYKVYDFVRYELSRANIRKDIQVI
                     DNVLPVIEQIKDTWHEADKKSKEERSRYK"
     gene            60316..60672
                     /gene="fliS"
                     /locus_tag="KRH23_001368"
     CDS             60316..60672
                     /gene="fliS"
                     /locus_tag="KRH23_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0044780 - bacterial-type flagellum assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar export chaperone FliS"
                     /protein_id="HHS5224652.1"
                     /translation="MELNLAELDKLSKEELLLMLVDGTVKYTNISKEALLNNDYLKAH
                     NELVRVQNIFTELMTTLDQNAGQWAKDMYKVYEFIKSELAIADENKDIKIIDDILPIV
                     KQIRDTWHEVYNQLKI"
     gene            60693..62216
                     /gene="fliD"
                     /locus_tag="KRH23_001369"
     CDS             60693..62216
                     /gene="fliD"
                     /locus_tag="KRH23_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009288 - bacterial-type flagellum
                     [Evidence IEA];
                     GO_process: GO:0007155 - cell adhesion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar filament capping protein FliD"
                     /protein_id="HHS5224653.1"
                     /translation="MSSISPIRVTGLSGNFDMEGIIEASMIRDKEKVDKAKQEQQIVK
                     WKQEIYRNVIQESKDLYDKYLSINSPNSIVSEKAYSSTRITSSDESIIVAKGSAGAEK
                     INYQFAVSQMAEPAKFTIKLNSSEPIVRQFPPNASGASSLTIGDVNIPISEQDTTSTI
                     VSKINSLCADNDIKASYSEMTGELIISRKQTGSSSDINLRVIGNDNLAQQIANDNGIT
                     FINDAGGNKFANVYGKNLEADVTDEHGRVTHISKEQNSFNIDNIDYNVNSKGTAKLTS
                     VTDTEEAVKNMQAFVDDYNKLMDKVYGLVTTKKSKDYPPLTDAQKEDMTTEEIEKWEK
                     KAKEGILRNDDELRAFVEDIQSAFFGDGKNIIALRKLGINESENYNKKGQISFNADTF
                     SKALIDDSDKVYKTLAGYSSNYDDKGMFEKLKDIVYEYSGSSTSKLPKKAGIEKTASA
                     SENVYSKQIAEQERNISRLVEKMNDKEKRLYAKYSALESLLNQYSSQMNYFSQAQGN"
     gene            62219..62554
                     /locus_tag="KRH23_001370"
     CDS             62219..62554
                     /locus_tag="KRH23_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein FliT"
                     /protein_id="HHS5224654.1"
                     /translation="MDKLKEKLNLYKDISLQIINLIEKEEYINISSKLGERQEIINSV
                     SEIDRNDFIQLYNRMELIEIDSRIRDILQGQLLEVKKELHEYKLTKQVNTMYYNLNRE
                     KVNIFNKKV"
     gene            62656..63528
                     /locus_tag="KRH23_001371"
     CDS             62656..63528
                     /locus_tag="KRH23_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0071973 - bacterial-type
                     flagellum-dependent cell motility [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellin"
                     /protein_id="HHS5224655.1"
                     /translation="MRVNTNVSALVANNQMGRNVNAQSKSMEKLSSGVRIKRAADDAA
                     GLAISEKMRAQIKGLDQAGRNVQDGISVVQTAEGALEETGNILQRMRTLSLQSSNETN
                     TAEERQKVADELLQLKDEVERISSSIEFNGKKLLDGSSTEIRLQVGANFGTNVAGTTN
                     NNNEIKVALVNTSSIMSKAGITSSTIASLNVDGASGTDAAKQMVSSLDMALKELNTSR
                     AKLGAQQNRLESTQNNLNNTIENVTAAESRIRDTDVASEMVNLSKMNILVQASQSMLA
                     QANQQPQGVLQLLG"
     gene            63621..65762
                     /locus_tag="KRH23_001372"
     CDS             63621..65762
                     /locus_tag="KRH23_001372"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HHS5224656.1"
                     /translation="MLLSIVMIVKNEEKILEKTLKSLTTLRNSIESELIIVDTGSTDD
                     TINISRKYTENVYFHNWNNDFSSMRNISISYAKGEWLLILDADEILIDSSTIVKFFKD
                     GLDKKFNSASIQLKNLYSYDKKLYGYCSVLRLFKNVDFRYHGKVHEQPIYKNPIFNNV
                     ADFEHYGYLFEDEEIRLNKVKRNEKLLFQELKENDNSPYTNYQLGKNFIILGKYQEAL
                     YYLEKSYELYSKLESAPGYLITSLVKTYLYLGKHKKCEKLCLKYIKKDMNNIDIYYYI
                     AQAQVDLGKYENSIDSYKRYIYLLDNYEISTQANSLFSDTDTVGLRDEAIITLIKIYY
                     KLEKYEFVISEYNNIEDVEKKKNVYFSLFMSLYKLNRFEDIKNYYKEVSNSKIEKNSF
                     YRNIEEVINNIKEDEKEYVYKILCDIEGNYGILNQIRTNKCVSIDKCKEILNEEKEII
                     YAYIIKIAFEEKIDLLDIFYEMEYVWIEKYLKYLLALERSFNLVLYKYIISRPNTSDM
                     EKIRVYKAISKVVLESISLSDEKYKEIFYFYIMYSYKYIRYIYSNLSDFELKKFVCND
                     LDKFTIEFKHLLDIKNRVNNANEKLEYIHSMRKLLNEYPFYNKIIKILICELEENIKE
                     SEEFKDLKDSFIISIENMIETGKINDAKLLVDDYSKTFVDDIKILNIKGILYMLENKL
                     DKADFMLKKALSLDVENEDTIYNIEYLKSLR"
     gene            65786..67663
                     /locus_tag="KRH23_001373"
     CDS             65786..67663
                     /locus_tag="KRH23_001373"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HHS5224657.1"
                     /translation="MNIPIVVNEKSKDIIKDWQYTCTNEDIKFTSIIILTYNQIEYTK
                     LCIESIRKFTPKNKYEIIIIDNNSSDGTVEWLKRQSDIKSVYNNKNLGFPKGCNQGIE
                     LATGENILLLNNDVIVTPNWLYNLNKALWSQDNIGAVGPITNACSYYQQIDVDYKSIE
                     DMFIFAHKINKSSINLWKYRLKLVGFCMLIKKTVLDNVGVLDELFTPGNFEDDDLSFR
                     MIESGYKLLLCQDTFIHHFGSVSFKENRNKYTDIMYINRRKFETKWGFNPEYSGMIRT
                     DLISKIDDSLEANINVLEIGCGIGATLLEIKNIYKNASIYGIEISESAGKLAKYSADV
                     LIADIEKVKLDYKKDFFDYIILGDILEHLIDPWKIVNELKQYLKKDGYLVSSIPNIMH
                     VSVLRNLVLGNFTYEDSGILDKTHLRFFTLNEITKMFNDSNYIINSITATSMPLSEID
                     NSFIDTICKESCKEMRQQYESYQYIVKASKILDTKRYSSISMVNLKYALMRIDNELDV
                     DSNLSYIFDNYNITEPCFVDDIEYLIDTFVINKATLLNRLGVEAFNRGLGDFSINMFM
                     TVLEMDRDDIDSIYNITSVLCELEEFDTAYNLIKNSSEKVQSESDIQEILCFIEGKKY
                     E"
     gene            67656..69770
                     /locus_tag="KRH23_001374"
     CDS             67656..69770
                     /locus_tag="KRH23_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family protein"
                     /protein_id="HHS5224658.1"
                     /translation="MNNDKICFITCVNDERLYEECLVYINSLDIPKNFSIETVALRGA
                     DSIASAYNKAMRETDSKYKVYLHQDTFIINKNFIHDILEIFKKNTDVGMIGVAGVKDM
                     PVNGIWWDSDKKAGKVYDSHTGKMDIYEFSNFEECFNEVMAIDGLIMITQYDVFWRED
                     KFDGWHFYDLSQSMEFRQNKYKVIVPKQNKPWCMHDSGVVNINNGYDEYRIKFVKEYI
                     NLDLYRENFYEFDKKKASTILKSNKHVMDCMKEELTEQLRLKNYKDVLGIVSKIAHFS
                     VFNHTGLYSCEECERALLECANNLPEIENTKLFTKKDLKRRKVLHVLSEGYSTGGHTR
                     LVKNWIEIDKDSVHSVVTTWQSDTLPDWLLKAIDDSGGEVISLDLISDDCLKRAMALR
                     KIAYDWADIVILYVHMWDTIPVVAFGVDGKIPILHVNHYDSTFWLGTSIADIVIDFSE
                     ASQLITLDKRGIDKSEILPMPLKEKEVFSKSEVRKRYNLEDDVTIILTIASERKYNSV
                     NDINYFKIAKTLIENTDNTIIIVVGVDTENLYWKTLSNVTDNRVICFGTTANIDDFYK
                     ISDIYMESFMVGSHTSKLDAILYDLIPVKFKNEVSPIFTNMWNFIDKFDYKNIKEVID
                     MIKRYNTSEFDRDRIKEKQSEIKHFVIDKHCIEIKNYIDKIYNEANHHKVKYDLYKND
                     EIEDYQLFVALYGYMVKNKNMS"
     gene            69779..70774
                     /locus_tag="KRH23_001375"
     CDS             69779..70774
                     /locus_tag="KRH23_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016755 - aminoacyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0044038 - cell wall macromolecule
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation glycyltransferase
                     FemA/FemB family protein"
                     /protein_id="HHS5224659.1"
                     /translation="MNNIHINKFEKSCEKNWDYFVENKSINGTFLQTRNFLNYHEEGK
                     FTDHSLIICKGEEILAVVPACETYEDGERIFFSHLGSTFGGIIIRSGFNDIRHVNAIT
                     NKLEIYLREQNFDKVYLKNTSRIFCKEDTSLLEYFLFKNNYMFYDELSMFLELSKYKE
                     DILANFKYSKRRDFKYSLKNNLTFKRLYSDEDIVCFFNLLSNCLDSKGAKVIHSVEEL
                     LEFKNNRLKDIVEFYAVYIDDIMICGSMVFNFQERVYHTQYLASNSTYNKYYPMIFLY
                     YNLIKDALERNFKYLSFGISTLNRGKYLDEGLATFKEGFGSSAICNRTYYKNINK"
     gene            70866..72098
                     /locus_tag="KRH23_001376"
     CDS             70866..72098
                     /locus_tag="KRH23_001376"
                     /EC_number="6.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HHS5224660.1"
                     /translation="MKRLMILGSIKYFENIVISAKKEGIYTIVCDNRIDTPAKKICDE
                     AIDVDVFDFDKIKSIAIDKKIDGILTGFTDSLMKPYVYIANELNLPCVISCNQLESVT
                     NKAIMKKYFKNNAIPTTDYCIIESLKDLEKIQRLNFPLVIKPVDGYGSRGVYFVSNME
                     ELIEKFEYSKEASQDGQVIIEEFYESEEIQGLAWVHNGESHVFYIGDRELVNIHTGRA
                     GKPDRLLYPSKYCFQYEEEIKSIYQNITQAFDIKNGPLYVQMLVGAYGIKVSEVMPRL
                     PGGCDYMAISQITDLDIGSLFANFSVNNEVNFDEIKKYNMHLSKCVYALPIYIRPGTI
                     KKINNIDKIENLDYVTQFLLLVKEGDTIELYEDERQDCGRVYGIANNIFDANIKKKCI
                     HEMIEILDENNENMIENF"
     gene            72118..73062
                     /locus_tag="KRH23_001377"
     CDS             72118..73062
                     /locus_tag="KRH23_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase"
                     /protein_id="HHS5224661.1"
                     /translation="MKLITHEQIMSLNISQKQGYEWIKESFLTKKDCQLPPKISMVEE
                     GHVFYNVMPSLNHNHMIGGIKMVTRLPGRNPSLNSEIFLYNMEDAKLKAILDGNYITA
                     FRTAAVAALAIDTFAKKDFNTIAIMGLGVTASAIMNMLSYTLKDKNINIKLLKYKDQA
                     ESFVKKYEKNEQFSFEICDTHEELIVDSDVVISTVTYTDEYLSEFKWFKKGALLLPVH
                     VMGFGNVDYLFDKVYLDDYNHLKHLENIDRYKYSCEFYDVLSKQAKGRENDDERIISY
                     NIGLSIHDILFANKIYELCETLSCEEIELKEPKEKYWI"
     gene            73135..73563
                     /locus_tag="KRH23_001378"
     CDS             73135..73563
                     /locus_tag="KRH23_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FdtA/QdtA family cupin domain-containing
                     protein"
                     /protein_id="HHS5224662.1"
                     /translation="MNRIDKFMDKYNLIRFVSIGNEYIGNLVALESNKVIPFDIKRVY
                     YIYDVPNNVKRGFHAHKNLEQVLVCLNGSVKIKCYDGVKETIFNLHKNDVGLYIGTGV
                     WHEMFDFDEKTVLISIASEHYNEEDYIRDYKEFLKYLNNM"
     gene            73641..74741
                     /locus_tag="KRH23_001379"
     CDS             73641..74741
                     /locus_tag="KRH23_001379"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012815981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008483 - transaminase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS family aminotransferase"
                     /protein_id="HHS5224663.1"
                     /translation="MNLLLVKFNNLLKQFQTHKEEYEQKIKDVMESGYYILGNEVKHF
                     EEEFANYVGSKYCVGLASGLDALIIAFRALGISKGDEVIVQSNTYIASVMGISINGAT
                     PVFVEPNEYYNIDSSKIEEKINSKTKAILVVHLYGQASNMKDIQELCDKYNLYLIEDC
                     AQSHGAKYDGKMTGTFGDIGCFSFYPSKNLGAFGDAGAIVTSNEEIADKVKILRNYGS
                     EKRYYNKFVGYNSRLDEIQAGLLRVKLKYLNEIEIEKSKIVDRYLNEINNPKVILPKI
                     ENNCTHVWHLFVLQVEKRDTFMEYLKKNGIESIIHYPIPPHLSEAYAYLGYKKGSFNI
                     AENYSDKVVSIPLFIGMEDEEVSYIIKIINEY"
     regulatory      75050..75140
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
BASE COUNT        29886 a         7948 c        13395 g        24204 t
ORIGIN      
        1 tataaaatac tcttaaataa ggtaggagaa aaatgtatgt ctaactttat tctaaatggg
       61 atttttagaa cagttatagt aagtagtcta agcattcttc tgatattgat tttcaagaaa
      121 aatgtattta aaagatttag caaaaaattt aattattata tatggatgat agttgttatt
      181 aaattatttt taccatttac atattatact tttacaataa atatcttgag aagtaaaaaa
      241 catattaata ttaataacat aaatttagag ggatttaata atgtttcaac tataagtaat
      301 aatattatat tgtacacttg gattataact gtagtagtgt atttaattta cactatattt
      361 aaatatataa aacttaaaaa tttaataaat gacttatctt atgatgttga tgatagagag
      421 attgtaaatc tttataaaaa tatattagaa gaatttaata taacaaaaga tataaaactc
      481 aaatactctt atgaagttga aacaccagca ttttttaatt catgtgtgct tttgccacca
      541 catgagtata aattgaaaga gttagactgg atttttagac atgagcttat gcattttaag
      601 agtagggacc tttatttaaa gtatgtaatc ctgtttttaa aaacagtata ttggtttaat
      661 ccatttatat atataatgga taaacatata gatttagatt gtgaacttta ttgtgatgaa
      721 agagttttaa aaaatcgaaa ttcagaggaa aaaaaggatt atgctttaac tattctaaat
      781 gcaatgagaa aaggttcaaa tacttcaaat aaatttatag ctggacttca taagcaatct
      841 gatattaaaa agagagttat gaatatgttt aatgaaaagt acaagaatgg tatattaatg
      901 gcattaactt tatgtttatt atcttctatt acttttttga aggttaattc aactagtatt
      961 gttaatctta atgtattacc taaaggattt gaagacttac gaactgttag cagtatacgt
     1021 ttttcagtta taggatttac atatgcagat gctcctaaaa atatgaggga agaatataaa
     1081 ataaattgtg aatcattagg tttgatacct aaagactctg ataaaataga agttggtata
     1141 gaatattatg acagtctatt gaatgattaa ataaatatta ttttaacaga tattaattat
     1201 aaagttttga atagtaattt gttgagaaat aaatatatcc ttataaaaat agatacttat
     1261 ataccaagaa taaaaaatag tcaagatagt acacaaggat atacttataa agaacttaaa
     1321 taagtgaaat aaattattaa ttataaggtt tataatttta aaaaattaga taaattcagg
     1381 tgtaaaatac tataaaacac aattcggaaa agtgtatgtt gaacttcatt taaaatggaa
     1441 tttcaaagtt gctatagtaa gtagtttaag cattcttctc atattaatct ttgagaataa
     1501 tgtatttaaa aaagttagta aaaaatttaa ctattgtata ttaatgatag ttgctattga
     1561 tatattatct aaaaaaatta agtatgaaaa gattactgtt aggacaatct tttcatactt
     1621 aatttttaat atttatatta tccaaaattt tcatcttttt aacttagaat ttgagaatca
     1681 ctattaggaa ataggctttg atttatgtag ggttaaaaat ttcacagaat atctaacttt
     1741 atactaaatc catcaaaaaa tatacgccat ataaaagcgc ataaaaaaac acataaaaca
     1801 atatttatgc gcactttaac ctcgaatggt acaaaattct ttacttttac agacccatat
     1861 tatataatta agtaaataat gtatatttag gtgacatatt ggataagcta atttatttat
     1921 tttattaata aataatacta taaaagttat ataaagtggt ttacaaaaaa gttacagata
     1981 gagcttttat taatgtattg tgtattagta ttttatcctt aggtacactt cacctacaaa
     2041 atagaatcat aagataatta tgggaaaatt ttaggaggtt tatcgtgaag aaaaagatat
     2101 taataccagt atttgcatca gttatggcat tatcagtaag ttcaattgta aatgcagatg
     2161 aagtaaatga ttcatctcaa aataaggatg ataaaacaaa tactgaatta aatttaggtg
     2221 aatataaaga agtaaaatat aaagttgcaa aaataaaaga tggagtagct ataaagataa
     2281 gagaagaagg tcaagttcaa aacatagctt attctggaga tgaatttacg gttttaggaa
     2341 ctcaaggaga atgggttaag gttaaagttg aagatggcga aggttggtta gctactagat
     2401 atgtagatat atctgaaggt gtaggatata ctaacgctga taaagtaaac ttaagaaaag
     2461 ataagagtga aagttcagaa gtaattgaag agctggaaaa aggaagttct ttattggttt
     2521 tggaagataa tggagattgg ttaaaagtta aagatgggga aacagaagga tatgtaaaat
     2581 catcttatat atctgataaa gctcctgtaa tagaagagcc acaagtaaac ccaagtattg
     2641 accaaaatgt agattctaca aataataatc aacaaaataa taattcaaat gtgccaacag
     2701 ctaactctaa tgcagttcaa gctgtactta acttggcata ttctaagcaa ggttgtccat
     2761 atgtttgggg agcagaagga ccaaacactt ttgactgttc tggatttaca caatatgtgt
     2821 atagaaatgc agtaggaaag aatataccaa ggacatctaa agcacaatct aaatatggac
     2881 aaactgtaag taaagcaaat ttacaaccag gagacttagt attctttaca actaatggtt
     2941 ctggttctgt tagtcatgtt ggaatatatg taggtggggg taatatgata cattcaccat
     3001 caacaggaaa aacagttagt gtaactagta taaattcatc atactataca gcaagatttg
     3061 ttacagcaaa aagaatatta taatcggttt gtaatatgac aaattgataa atacataaat
     3121 atatataaac gctctatatt atatttaatt taatcatgga aacaaaaaat gattatattt
     3181 taaatgtact atagagcgtt tttgtatcac tttaaatcta atcaagattc aagttaatat
     3241 gactgttaaa taggagcctt ttcatatgat gattatttgc gcaatccctt gacaggatag
     3301 ggcaaaggtg gtaagctact aacagtacaa aaatactttt aattttagtt cagagaggct
     3361 aaaaaaggag gacgaaagat gttaaaatca agaaatttaa tccaaccaga agacttttca
     3421 atagaagaaa tagatgaaat attagaatta gctcaaaaaa taattgacaa tccgtcaaaa
     3481 tattctcgta tatgtgaagg aaaactatta gctacattat tttatgaacc atcaacaaga
     3541 acaagattaa gctttgaatc tgctatgaac agattaggag gacgtgtagt aggcttttca
     3601 gagccaaatt catcctctgc atcaaaaggt gaaactctag gagatacaat gaggatagta
     3661 tctggttatg ttgatataat agctatgaga catcctcaat caggtgcagc ttcagaagca
     3721 gctagatata cggaagtgcc atttataaat gcaggagacg gcaaaaacca gcatccaact
     3781 caaacactta cagacttact tactataaaa tcattaaaag gaactttaga aagccataca
     3841 ataggattat gtggtgattt aaaatatgga agaactgtgc attctttggt taaggctatg
     3901 gcaagatata aaaatacaaa gtttgtattt atagcgcctg aagagttaaa aatgccagat
     3961 tatataaaag aagctataaa gggacatgca tattatgaaa ctaataattt ggatgatgtt
     4021 ataggaagct tggatgtttt atatatgact agagttcaac aagaaagatt tgaagataaa
     4081 tcagagtatg aaagacttaa aaactattat attttaaata aagctaaatt agaaaaggca
     4141 tctaaagata tgttagtaat gcatccatta ccaagagtaa atgaaataga catagatgta
     4201 gatagtgatg atagagctgt atattttaaa caagctaaat atggaatgta tgttagaatg
     4261 gctttaataa taaaactttt aggtataaat gaagactaat agttatcata taatagtaaa
     4321 acaaaggaga ttttgggatg tataaaattc tggaaaatat atatataggc gaagatatgt
     4381 atagaatgaa agtaaaaggt aattttgaag gtaaaatggg acaattctat atgttaagag
     4441 catgggatac ttatccagta ctttcaagac ctataagtat acatgatata gatgaagaag
     4501 ggataacttt tctttataaa gtagtaggag aaggaactca aattttgagt aacctaaagg
     4561 taaatgataa tataaaatta gaaggccctt atggtaatgg atatgataag gttgatggaa
     4621 aggtagctct agtaggagga ggaatcggtg tagctccact atatttggtt gctaaaaata
     4681 taaaaaattg tgatgcatat cttggcttta gagaagatgt tatattagaa gatgaatata
     4741 aacaagtatg taataaagtc tatacaacag taggaaatac ttttgtaaca gatataattg
     4801 atgttgagaa atatgattat atattaacat gtggtccaac tccaatgatg gaaaaattag
     4861 ttaagatggt agaaggtact aaaacgagaa ttatggtatc tcttgaaaac catatggctt
     4921 gtggagtagg tgcctgttta gtatgtacgt gtaaaactaa tggaggaaat aaaaagactt
     4981 gtaaagatgg tccagtgttc tggggagagg acgtgatttt taatgggtaa tttaagtgtg
     5041 aaatttggaa gtgtagaatt taaaaatcca gtaataatgg cgtctggaac ttttggattt
     5101 ggaaaagaat ataatgagat ttatgatata caaaaacttg gtggtataag tagcaagggt
     5161 cttactttaa ataaaaaacc tggtaacaat ggtatgagag ttcatgagac atcatccggt
     5221 atgatgaata gtgttgggct tgaaaaccct ggagttcaag gatttataga ctatgaatta
     5281 ccttttttta gtaaactaga cttagtcaga atagctaatg ttggaggtgg gacattagaa
     5341 gactacttat taggggttca aatgttaaat gacaagcctg tagacattat tgaattaaat
     5401 atatcttgtc caaatgtcaa agctggtgga atggcttttg gtataaaaaa tgaagtggca
     5461 agagaagttg ttcgtgaggt aagaaacata acgaaactgc ctttagtaat aaaattatca
     5521 cccaatgcag aagatattgt aggaatggca aaagtttgtg aagaagaagg tgctgatgga
     5581 gtttcattag ttaatacttt taaagcaatg gcaattgata taaaaaatag aagaccagta
     5641 tttgaaaatg tatatgctgg gttatctgga ccagctataa aacctatagc tttgagaatg
     5701 gtacatgaag tgtgtaaaaa tgtaaatata cctgtaatgg ggatgggcgg aataactaaa
     5761 gccacagatg ctatagagtt tataatggca ggagctactt gtatccaagt tggaactgca
     5821 aattttatga atcctagaat aggtattgaa ataatagatg gaattaatga atttatggat
     5881 agagaaggaa taaaaagttt agacgaaata agaggaatta tataaggtag aataaatagt
     5941 attttaaaga taaaaaatat agattaaata aacaataatt ttataacatt aacatggagg
     6001 aaaaataata tgagtaaagt agatgtagtg gatatattaa agaaaagtga tgcattgttg
     6061 gagggacatt ttttattatc ttcaggaaaa cacagtaata gatacgtaca atgtgcaaaa
     6121 gtattaagat tcccagaata tgctgctgag gtattaagta cagttgttga acaaataaaa
     6181 gacttagata tagacttagt agtaggacca gctatgggtg gagtaatagt ttcttatgag
     6241 ttaggaagac aattaggaaa agaagctgta tttactgaga gaaaagacaa tacaatggag
     6301 ttaagaagag gatttgaagt taaaaaagga gcaaagataa taattgctga agacgttgta
     6361 actactggta aatcaactat ggagacaaaa agagtattag aagccttagg tggagaagtt
     6421 gtaggtgttg catgtatagc agatagaact aatcatgata taggtatgcc tatatatagt
     6481 gctataaaac ttgatattca agtttatgaa tctgatgagt gtcctttatg taaggaagga
     6541 aaattaccag ttgttaagcc tggaagtaga gagttcaagg aattagggat gtaataaaaa
     6601 cttaattatt tatagtgtta cttaaaaaat gtaaattttt tagagtaaaa atttgtaata
     6661 taacatataa cttaaaaata aaaagcagtt agccttataa atgaaggtta gctgtttttt
     6721 ttgttaaaaa tatatttaca aaataagaga tagtagcagt acaatataag tataaggtaa
     6781 aagtattata tattagggag gggtaagtat gaaaaatcaa ttaaatgaaa atcataaaaa
     6841 ggttgtattt tttggagtag gtgctgtagg agctactttt gcagaacaat tttttaactc
     6901 taaatatgat tttaaaattc tttgtgataa tgaaagaaag aaaagatatt tagaagaagg
     6961 atttataata aatggaaaaa ggtatgattt tgattatgta actaaagatg agtataaaca
     7021 agaggctgat tttataatta taggtctaaa atataataat ttaaaagaaa atataaaaga
     7081 attagatgga ttagttggaa aaaatacagt tataatgtct ctgctaaatg gagttgatag
     7141 cgaagagata ataggagaaa gatttggaat tgaaaaaatg gtatattcat atgttaccaa
     7201 tatagatgca aagaaaatca ataataatat tatacacact actaatggga taattgtatt
     7261 tggtaacaaa gataatagtg aagatagaaa aactaatata ataaccgaag tctttgatga
     7321 tgtaaatata gaatatactt tatcaaaaga tattcaacga gatatgtggt ggaagtacat
     7381 ggttaatatt ggtgtaaatc aaacttcagc tatacttggt gcaccttatg gagtttttca
     7441 gagttctgag catttaagag aattagcaaa atctgcaatg agggaagttg ttgctatagc
     7501 acaagcaaaa gacatatctc ttacggaaga tgatgtggaa cattcattac atagaatact
     7561 agaacattca aaagaaggaa gaacatcaat gcttcaagat gtggaagctc atagacttac
     7621 agaagtagat atgttttcta agaatatctg caaacttgga aaaaaatata acatacctac
     7681 tcctataaat cagactttct tttatatgat aaaagtaatt gaaagtagat tttaaagggt
     7741 ctttgtaaga aatattgata attattgatt ttaaatttta ttaatgttat atactattta
     7801 agttactaaa tatttttaac tcttcaatga aaatagttgc tgcttttgat aaagttatat
     7861 cttttggaaa tatatatgag aaatgtctgt tgtagctgct tccaagctct atgacagaca
     7921 gctcattgtt tagaacaggt aagcttgtca ctagattaga gactattgta attcctaaat
     7981 tatttctaac agattctttg acagcataat tacttccaaa aaccatcata ctttttggaa
     8041 taatttcttt aacacttaaa aacatatcta aataatctct ggttccagaa ccatcctccc
     8101 tgactatcca tttttggttt tgaagtttat caaaactaaa atcttttaat aaatgactct
     8161 tgtatggaag tgctaaaacc atcttatctt caaaaaaata ttcttgaata aatgaagggg
     8221 aagagcaagt gccttcaata agaccaatgt ctaaaatata atccttaaca tgagaagata
     8281 ctattgatgt attttttata aaaacttcta catctatgtc aggatacttt ttagaaaata
     8341 atgctaaaaa atttggtaga atatactctc caatagttaa acttgcgcca atctttaagt
     8401 gaccagttat agcatctgaa acttggctta catcatgata agtaatattt aaaagattta
     8461 atatttcttt agctcttttg tacaagattt gtccactttc tgttataaaa atggtttttt
     8521 gtttaatgga cctgtttata agaacaactt taaaataatt ttctagattt tttatgtgtt
     8581 tacttacact tggttgtgat agatttaaat attccccagc tttagtaaag tttttgtatt
     8641 caacaacagc tacaaatgtt tttaattctt caaacaattt tttgtctcct ttacctaatg
     8701 aaattttaca ttttttatat actttctaca gataattata ctatatataa taaccattaa
     8761 aaacattaat cattacgata ttatatattt attttactta tggttattac aattatatac
     8821 tattgctatg aagaaaacta tattaattat aaggtaggta tattatgtta aagaaaaaaa
     8881 gcagtttgac attaaaaact ataagggaaa tattaccagg actgtttgta tcagtattag
     8941 taggttatat tagtatattt atttctattt taattcctaa ggtaggggca gcatcaattt
     9001 ctatattttt aggtatgttt gtaggaaacc tatttttaaa tcaaaaggta tttcaaaaag
     9061 gttataaatt ttcagagaca gatttgttat catattcaat agtactatta ggagcaacac
     9121 tcagtgtatc taccttaata gacttaaaag tttcaggaat tttatttata atattgcaaa
     9181 tgacaataac aataatagct gcactttata taggtaaaaa actaggattt gaagaaaact
     9241 ttagatttct aatggcaagt ggaaatgcag tatgtggttc ttctgcaata ggagcaacag
     9301 ttccagtggt taatgcgaca gataaagaaa agggaattgc agtaactatt gtaaatgtta
     9361 ctggtatatt tcttatgttt ttacttccaa taatatctca atttttatat agccatgaac
     9421 ttgtaaaaac ttcagcaatg ataggtggaa ctttgcaatc aattggccag gttgtagcaa
     9481 gtggagcaat tgttggagaa aatgtaaaag atttagctac tatttttaag atagtaagag
     9541 taatatttct agttgttgtt gtattagtat ttggacatat gaaaaatcaa tctaataggg
     9601 aaattcttga agaagaaaag gatgagataa aaaagaaaaa agtgactata ccatggtatg
     9661 taattggatt ctttataact tgtgcacttt tttcaatgaa cattatacca aaagaagtat
     9721 ctgtgttgtg caaagaaata agtaacaaac tagaaataat agctttagca gcaattggat
     9781 taaaggttaa tgtaaaagat ttagtgaaac aagggaaaga agtttcttta tatggtttat
     9841 ttgtaggtac agtacaagtt gtatcagctg tagttttaat aaaaatattt atatagtata
     9901 aaaatagtat ttgtaatact aatttgatta attaaaataa tatgatacta ataatttata
     9961 atataaataa aaaatgaatt tcgataagtt taagtgggta taaacttata gaaattcatt
    10021 ttttatttaa ggtaaaaatt taaagtaaaa tattatttta cataataata accttataaa
    10081 ttttgaaatt acttatcttt gtgttaaaat aagtaaaatg cacatattag agctaagttt
    10141 ttaagtaaat aaacaaaatg aaaatataaa tattaaggag atttggtata tgaatgttta
    10201 tgaaaaaggt aatggagtta tactagaagg agtaacagat tttgacccag tacatatatt
    10261 tgagtgtggt caatgtttta gatggcacaa acaagaagat ggctcataca ctggagttgc
    10321 aaaggggaga atattaaatg tcaaaaaaga gaatgataaa atatatttaa ataatactaa
    10381 tttaaaggag tttaacagca tttggtataa ttactttgat ttaggaactg attatacaga
    10441 aataaagaat aagctaaaaa atatggatga atatttaaat aaggctactg aatttggatg
    10501 gggaataaga atattaagac aagatggatg ggaaatgctt atatcattta taatttcctc
    10561 taataatagg attcctatga tacaaagagc gatagaaaat ttatcaagaa agtttggtaa
    10621 gtatataggt gaatatgaag gtaatgaata ctatgcattc ccaacaccag aagaactaaa
    10681 taaggcctca caagaggaaa taagagcatg tcaaacaggt tttagagata agtacataaa
    10741 aagtactaca caggcagtta tagagaataa tgatgaggta tctgaatata caaatttaag
    10801 tacagaggat tgtagaaaag agcttttaaa atttaatgga gtaggaccaa aagtatgtga
    10861 ttgtattgca ttatttggta tgcaaaaata tgattctttt ccagttgatg tttgggttaa
    10921 gagagttatg caagaatttt atatagatga agacatgagt ttacctaaaa tgagaactta
    10981 tggaatcgat aaatttaaag aaatgtctgg atttgctcaa cagtacttat tttactatgc
    11041 aagagaactc ggtataggaa aataaattaa gggggagaaa ttatgggagt aataggaaca
    11101 atatttctgt tctatttaat tatatcatat ctagctggag ccataatttc tgtgattata
    11161 ttacttgaaa atagagaccc tgcaaaaaca atgtcttggc tattgatgtt tattatattt
    11221 ccaggtgtag gtttaatgat atatgctatt tcaggtagaa atattagaaa aagaaaatta
    11281 tttaagactc aaaaactagc taataatata aaagaaaaga aactatttga tacattagaa
    11341 aagataacag aaatagttga attagaaaaa gaatctataa aacaaaataa gcttttaaga
    11401 gatgaagagg atggtagtta tagaaaaagg gtaataaata tgttgttaaa gactggtatg
    11461 tttcccttta ctaaaaataa taaagtggat gtatttgtag atggaaatga aaagtttaaa
    11521 agacttatag aagatataag agaagctaaa gaccatattc atttagagta ctttatcatc
    11581 aaagatagtg aaataggtag ggtgttaaaa gaagaactta taaaaaaggc taaagaaggc
    11641 attaagataa gaattttata tgatgatgta ggatgctgga gattttggtt taatagaaaa
    11701 tttttccgag aaatgaggga agtaggtata gaaattgcag catttttacc tacaaaattt
    11761 cctataatag gagggaaatt aaactataga aatcacagaa aaattgttgt tattgatgga
    11821 ataattggat atacaggtgg aataaatata ggagatgaat atttaggcaa aaatgataag
    11881 tttggatatt ggagagatac tcatattagg attaagggta tttctgtata catgcttcaa
    11941 atgacatttc tgattgattg gtattatacg acaaaagaag tattagtgac taaaaattat
    12001 ttcccaagtg tagggaatgt tggtgaaagt atgatacaag ttgttgcgag tggtccagac
    12061 agtgactggg aagatattca ttatgcttat ttttctgcaa tatgtcaggc tagaaaaaat
    12121 gtttatatag aaactccata ttttattcca gatgaaagtc tactaaaagc tataaagagt
    12181 gctgctctta gtggagttga tgtgagaata atatttccta aaattgcaga ccacaagata
    12241 gtaaatatag catcttattc atattttgaa gaaatattaa gagcaggtgg taaagtttat
    12301 ttatataata aaggatttat acattctaaa gtcgtaataa tagatgataa aattgcttct
    12361 gcaggtacag ctaatatgga tttaagaagt tttatgctta actttgaggt aaatgcattt
    12421 atctatgatg aagaagttat tagggtaatg acagatgatt tctttgagga tttaagtcac
    12481 tgtgaagaac ttaatttgga ggtatttaag aatagaaata tcatacaaaa aatcaaagaa
    12541 tctgtagcaa gattattttc accaatatta taaaaaatta ttaaaaaagg tattgaaaat
    12601 tatgtgtgat tggtatatta taataattgt tagcactcta ttagatagag tgataataaa
    12661 taaaaagtat atatataaat ctacatatat aagtagtatt aatttaaaaa taactaaaaa
    12721 cataggcgaa ctagtctata cttaatattt taggaggcgt gaataatgaa aataagacca
    12781 ttagctgaca gagtagtaat taaaaaagta gaagcagaag aaaaaactgc aagtggaata
    12841 gttttaccag gagcagctaa agagcaacct caaatagctg aagttgtaga agttggacca
    12901 ggtggaatag ttgaagggaa agaaataaaa atggaattga cagtaggaga taaggttata
    12961 ttccaaaaat attctggaac agaggttaag atagaaggac aagaatacac aatactaaga
    13021 cagagtgatg tattagctgt tattgaataa atatagaata aatttattag gaggggttta
    13081 aaatggctaa agaaattaaa ttttcagagg aaacaagaag agctttagaa gctggtgtaa
    13141 ataaattagc agatacagta aaagtaacat taggacctaa aggaagaaat gttatattag
    13201 ataaaaaatt tggttctcca cttataacta atgatggagt aactatagca aaagagatag
    13261 aactagaaga tagatttgaa aatatgggtg ctcaattagt taaagaagta gcaactaaaa
    13321 ctaatgatgt agctggagat ggtactacaa ctgctacagt tttagcacaa gctataataa
    13381 gagaaggttt aaagaatgta acagcagggg ctaacccaat acttttaaga aaaggaatac
    13441 aaaaagcagt aacagtagca gtagaagaat taaaaaatca atcaagaata gtagaaacac
    13501 aagaggctat atctcaagtt gcttctatat ctgctggtga tgaagaagtt ggaaaattaa
    13561 tagcagaagc tatggaaata gtaggtaaag atggagttat aactgttgaa gagtctcaaa
    13621 ctatgaatac tgaattagat gctgttgaag gtatgcagtt tgatagagga tttgtttctg
    13681 catatatggt tacagatgta gataaaatgg aagcagtttt aaacgaccca tatatattaa
    13741 ttactgataa aaaaatatct aacatacaag aattattacc agttcttgaa caaatagttc
    13801 aacaaggtaa aaagttattg ataatagctg aagatgtaga aggtgaagca ttatctacat
    13861 tagtagtaaa taaattaaga ggaacatttg atgtagtagc agttaaagct ccaggctttg
    13921 gagatagaag aaaagaaatg cttcaagata tagcaatact tacaggtgct caagtaatat
    13981 cagaagaatt aggttatgat ttaaaagaag ctgatttatc tatgctaggt agagcttcat
    14041 ctgttaaggt aactaaagaa agtactacaa tagtagatgg ttctggagat aaaaaagcta
    14101 tagaagatag agtaactcaa attaaacatc aagtagagca aactacttca gattttgata
    14161 gagagaaatt aatggaaaga ttagctaaac ttgctggagg agtagctgtt gtaaaagttg
    14221 gagctgctac agaagtagag ttaaaagaaa gaaagttaag aatagaagat gctcttaatg
    14281 caactagagc agctgtagaa gaaggaatag tagctggtgg aggaactgct tttgttagtg
    14341 ttataccggc aataggaaca ctaattgaga gtttagaagg agaagttaaa ctaggtgctc
    14401 aaatagttaa aaaagcgtta gaagagccat taagacaaat agctataaat gctggtcttg
    14461 aaggtgctgt aattgtgcaa aatgttgtta attctgaagc agaaactgga tttgacgcat
    14521 tgaatgaaaa atatgtaaat atgatagaag ctggtatagt tgacccaact aaagttagta
    14581 gaagtgcttt acaaaatgct gcatcaatag caagtacttt cttaactact gaagctgctg
    14641 ttgctgacct tcctgaaaaa gaagatgcag gaatgccagg aatgggtggc ggaatgcctg
    14701 gtatgatgta atttaaaaaa tttaaaatat aaattttaat ataaagaact atttcgactt
    14761 agattttaaa ctctaagttg aaatagttct tttgtatata tctaattttt gtatatctat
    14821 aaattcaata cacatattta gataatcagt atctagtttg taataatatt ttagagtagt
    14881 attgttattt tttaggttat gattttagat atatattaat taaggtataa ttgttgatag
    14941 agaataaatc aaatttaaaa ggatgcgata atatggactt aagaaaattg cttgaagaag
    15001 ttaaaaatga aaatattgat atagattttg cgttagaaaa gttaaaagat ttaccttatg
    15061 aagaccttgg atatgcaaat atagaccatc atagagaatt aagaaatggg tatccggaag
    15121 ttatttattg tgaaggtaag agtgatgagc atattttagg gattattgat aaaatgaatc
    15181 aaaaaagttc taacatattg gggacaaggt gcagaaaaga aacttttctg aaaattaaag
    15241 aaatctataa tcatgctgag tacgaagagg cgtctaaaat tcttaagatt caaaatcatg
    15301 atatagagaa tataggaaag ggtaaaattg tgattgctac agggggaact tctgatatac
    15361 cagtagcaga cgaagcttat catacagcta agtttttagg taatgatgtt gatagaatat
    15421 atgatgttgg agtggcaggt atacataggc ttttaaataa aagacataaa atagatagtg
    15481 ctagagtaat agtagccgtt gcaggtatgg aaggtgctct tgcaagtgta attggtggac
    15541 tggttgatgt tccagtaata gctgttccaa cttctgttgg atatggagca aattttggag
    15601 gattagcagc attactagct atgttaaata gctgtgcatc tggaatatct gttgtaaata
    15661 ttgataatgg atttggagca ggatatttag catcaatgat aaataaactg taaatacatt
    15721 gatataaatt aaacaaaact atataataaa atttaatttc tattatattt ttactattaa
    15781 aattgaggag acatatatga gtgaaaaaat actttatttt gatataataa gcggtatatc
    15841 aggggatatg acccttgcaa gtttattaaa tttaggtgtg cctaaggaaa tttttttgga
    15901 ggaaattcat aaactaagaa tgagcgatga atttaatata aacatcagct cgaaaactga
    15961 aaatggaata gtaggtacaa aagtagaagt aattacaaaa gaaaaacata cacatagaaa
    16021 tttagtggat atatttgagg ttatagataa aagcactcta aacgaaaatg taaaatctaa
    16081 agcaaaaaaa atatttatgg taattggaga agcagaagca aaagttcatg gaactacaat
    16141 agacaagata cattttcatg aggtaggggc tatagattca attgtagata tagtaggagc
    16201 ttctatatta gttgacttac tttgtgtaga taaagtttgt gctagtacag tgtctgttgg
    16261 ttcaggattt gtaaaatgtg aacatggaat tatacctata cctgcacctg caactataga
    16321 aattttaaaa ggtgtgccaa ttaaattaaa taatgtaaat ggagaatgta caactccaac
    16381 aggagctgca atcataaaag tcttgtgtga tgagtttgta gatgagcttg aattttctcc
    16441 aaagcaaatt ggatatggta taggtcataa gaagtttgaa gtaccaaata tactcagaac
    16501 tgtattaggt gaaaaaaaaa agaagaatta atttatgaaa ttagtgcaaa cattgatgat
    16561 atgtcttcag aaatctattc ttatttgtat gaaaaaatat tagatgagaa agcattggat
    16621 atttatacag agagcattta tatgaagaag aatagaccag caacaaaagt atcaatttta
    16681 tgtaatgaat cagatttaga aaaatttatt aaaatattac ttttagaaac tagtactttt
    16741 ggagtgagat ataatgcata taatagagaa attctagaga gaaaatttgt aaaattagat
    16801 acaaaatatg gagtggttac agtaaaacta gggtattata aaggaaaact agtcaaggct
    16861 actccagaat ataatgaatg taaaactata gcaaaaaatg aagatattcc tataaaaaaa
    16921 gtgtttgctg atataaattt tagaataaaa gaagaattta gtgaaaactt attgacataa
    16981 gtaataaatt ttgataaatt aatattcagc cttattaaat aaaagtaaac agaaaaaaat
    17041 atataaaata taaactcact cgtatatgct cagaaatatg gtctgagagt ctctaccaag
    17101 ataccgtaaa tatcttgact atgagtgaaa ttattatacc aaaagaccta gttaagtaaa
    17161 tgtgtaggct gagttaaact ccctatgtgt tggctataag ataaaggtat tttggaagcc
    17221 tgtatagtaa tttcactttt gctagaaatt atggaagtta ctatacaggt tttttgtgta
    17281 aaaagattta atataattta gactgtattg tgttaaaata aatatataaa aactatatta
    17341 tacaaggaga gatgtaaatt tatgaaacat gaattagtac ttgtaataga ttttggagga
    17401 caatataatc agttgatagc tagaagagtt agagaaaaca acgtatattg tgaaatactt
    17461 ccatgtactg caagcataga aagaataaaa gaaaaaaatc ctaaagggat aatatttaca
    17521 ggcggtccaa atagtgcgta tttagaagat tctccaacaa tatcaaaaga aatatttgaa
    17581 ctaggagtac caatacttgg aatatgctat ggtattcaaa taatgtctca tgtattgggt
    17641 ggagttgtaa gaaaaggtaa taaacaagaa aaagaatatg gaaaaacagc tataacttat
    17701 ggaaaatcat cattatttga aggaataact acaaatagtg tatggatgag tcatacagat
    17761 ttaatagaaa aagttccaga aggatttact atagttgcaa atactaatga ttgtccagta
    17821 gcagctatgg aaaatgtaga acgaaaccta tatggagttc aattccatcc agaggtagaa
    17881 cactgtttgg aaggggacaa gatacttaca aacttcttat ataatatttg taaagtaaaa
    17941 ggtgactgga ctacagattc attcatagaa gataaaataa aagaattaaa agaaaaaata
    18001 ggcgataaaa aagctttatg tgctttaagt ggaggagttg attcttctgt tgctgcagtt
    18061 cttattcata aagcaattgg ggacaactta acttgtatat ttgttgacca tggtttactt
    18121 agaaaaaatg aaggaaatga tgtagaaaga atatttagag agaaatttga tataaattta
    18181 ataagagtta atgcagaaga tagattctta tctaaattaa aaggagtttc tgaaccagaa
    18241 gctaagagaa aaataatagg tgaagaattt ataagagtat ttgaagaaga atcaaataaa
    18301 ttaggaaaaa tggatttctt agtacaagga acaatctatc cagatgttat agaaagtgga
    18361 catggaaatg ctgctactat aaagtctcat cataatgttg gtggaatccc agaagatgta
    18421 gacttccaag aaattgtaga accattaaga gagttattta aggatgaagt tagaaaaata
    18481 ggattagagc ttggtataga agaaggatta atatttagac atcctttccc aggaccaggt
    18541 ctaggaataa gagttatagg tgatgtaact aaagaaaaat gtgatatatt aagagaagct
    18601 gatgctgttt atatggacga gcttagaaaa gcaggtttat atagagaaat atggcaagct
    18661 tttgcaacat taccagatgt taagactgtt ggagttatgg gtgatgaaag aacatatgct
    18721 tatttagttg gtttaagagc agttacttct tctgatggaa tgacttctga ctggtataag
    18781 atgccttatg atgtattaga aagaatttct aatagaataa taaatgaagt tgatggagta
    18841 aatagagtag tttatgatat aacttctaaa cctcctggaa ctattgaatg ggaataaaat
    18901 atagaatgcc aaaaatccac ataaatacag gatttgaggt ctctcttact tctatgttat
    18961 actggtttga tactatcaat atttgccagt atcttatgga ttaataagca aaaaacatcc
    19021 tgctgaatga taaattcagc ggggtgtttt tattttgttt tagaactcct ttgctctgaa
    19081 actcgaagta tttaacactg atgatgttgt tatcttttag ttccttttgt gtcatgctct
    19141 gaaagacaaa ttgatacaat aaaaaagtaa tttcttaatc attgatggag atatgtattt
    19201 atgttactct tgatggtaat ttgagtaata ttgttcatag ctttttatat tcacttaatt
    19261 agaaaaccat ttggtataat cataaataaa cttgatgata taatagaaaa gatttataat
    19321 tattagaagt atataaaagt attttatgtc tatgaaatgt atgtctataa aacatataga
    19381 tgacttttgt atattaatgt atgaatattg atattataga agaattgagt tgtcaatgat
    19441 actaaatcaa atatttatag aagctggagg gattatgaga aataaaataa ttataggaat
    19501 tgctttttca cttgtattac taatgtctgg atgtgcttca aaacaaacag cagaaataaa
    19561 cgtattagca actactgatt tacatggagt tataccttat gagttaactt cttatgtaaa
    19621 agaagaaaga aaaaaagata aaaatctaac tttagtagat gcaggagatt tttttgatag
    19681 tggcgaagta tctggttcta gcatggatag ttattttagt gctaggtata aggatattga
    19741 taataacact gagcgttaca ttgagacacc tatttcaaaa gatatgaaag aggtaggtta
    19801 tgatgttgca gttcttggga atcatgaatt tatatccaac aataaatttt atctagataa
    19861 tatgatatct gattttgaga aacaaaaaat aaatatttta tcggcaaata cgtataaaaa
    19921 aaatggagat agttatacaa aaccatacat aataaaaaat attaatacac ctgaaggaaa
    19981 cgtaaaacta ggaattttag ggcttactat aaaagaagtt ggtgagagga aacagtggaa
    20041 agatggaaaa cttgttgact ctaagtcttt agaactaaaa gaccaagagg gttacaatgg
    20101 tgaattgtat atgaatgatt tagtagaaga tgctaaaaag tgggttggta taatggaaaa
    20161 agagaagcct gacattatag ttgctgtggc acatacaggt gagaaaccta agaaacctaa
    20221 aaacccagga aatagaatac aagacttagc tcaacaagtt gatggaattg atgctatagt
    20281 tgcaggtcat aatcatgttc aaattgagca acatgattat aaaaataaat caggagaaaa
    20341 tgttatagtt actgagccag gaaagcatgg ggaatgtatt tctaagatta attttaaatt
    20401 agaaaaaaac aatgataaat ggaatatagt tgacaaatct agtaaattaa ttaaatttga
    20461 aaaaaatcaa gaaagtgata aatttggaga atttatttct tcaattaata aagtaagtaa
    20521 agataagaaa gaaataagat tatcagaagt aaagactcct gaatgggata aaatatatgt
    20581 ttttaaatct ggaacatctg cagatgatat atataaaaca ataggatata aatggagaaa
    20641 tatatcatct ccaaagggtg atgacatggt gcagattgtt gtaatgaata ataataagcc
    20701 tgttagctat gtatatggtg aagctgaagt tatgccaatt aatataaaat gtgatgaatc
    20761 agagtataaa gataatgttg taactattta tcctaataaa aatgataaat ttaaaattga
    20821 aaaaggtaaa caagaatata gtattaattt aaaacatata caatagaaac ttttatctta
    20881 tttaagttta gattgtactt aaaataaagt gtgtattatt ttaaaaattg atgataatta
    20941 aaatcacaac attaaggaat agtacacact ttttatgcta aaaaatagaa tgttaaaaaa
    21001 ttaaaccttt aaattaaagt acattgctta tattatccaa tattatcttc aaaggttgtg
    21061 taatattttt atccttatgt aatattgcta acattttatt ttccatatct atcccatcta
    21121 attcaatcaa tcgcaatttt ttatgtaaga gtgaatctaa taataaattt tctggcaaaa
    21181 tggttatacc taaccctgct tgtgcagctt taataagtgc aaaagaatta acactttccc
    21241 aaacaggata agctttttgg tttgaaagag ataatacact gtccaaagta tcgcgaatgg
    21301 cacttccttg ctcacgtaac aataacggaa acgtgcataa ctgtcgtaga gataaggctt
    21361 gtttagataa aggaaaagtt ggagcacatg caacacataa cttataggaa cctaataaaa
    21421 ttgtacggaa tgctccctgt ggttctatac cttcccaaaa acatatatca gcttctccac
    21481 tttttaaaat atccatagct gaattagcac tttcgacacg tacattcact ttaagagatg
    21541 ggaatgaatt ttttagtcga cttaaaattg gtggaagtaa aaaagaggca attgtaatgc
    21601 tagaaacaat gtttataggt gtacattcct ctaaacgact gattcttttg tctaaattac
    21661 gacaagcagt taagatacta cgtgcttctt ctaaaagaga aatgccacag cgagtaagac
    21721 atacccctcg tggtagtctg tcaaataatg ctgtttcagc ttgttgttca agttcagcta
    21781 tagcatgaga tacagcagat tgtgtgatat gtaatttttt tgcagcacct gtaaaagtgc
    21841 ctgtttgttc aattgcttct aaaatctcta aatatcgtat gtttatcata ataaatatcc
    21901 tcactagaca tgaataaaat tgattaattc cattaaattc tatcatttta cagattacaa
    21961 agcaacaggt atactgaata atatgaagtg aaaagaagga ggaatatttt gaatcaaagc
    22021 agaaaaacat atttttggct tttaattatt aacttgttta ttagcacatt cacttttggt
    22081 ggagggtatg tagttgtacc tatgattaga cgttattttg taaatcaaaa gcaattcttt
    22141 acagaagatg atttgatgag catggcagca gttgcacaat caactcctgg agctattgca
    22201 attaatttat ctgctttggc aggttatcga gtagctggta ctttaggggt tgtcattagt
    22261 tgtatagcag ctataatacc tccactcgtt attcttggat tagtatcagc attttacacc
    22321 acttttatat ctaatgccat tgtaactgca gtattaaaag gaatgcaagc tggtgttgct
    22381 gcactaattg tggatttgat tattgacatg tgctctatga tattaaaaca acgttctcta
    22441 tttttatcag ctatgatacc tattgctttc tttgcaaact ttgtgatgag tataaatgta
    22501 atttttatat tatctgtttg ctgttttgta tgtgtaatgc aagctttcta caagaagagg
    22561 gaaaataaat gaatacaatt tggaacttat tttttatatt tttaaaaata ggattgttta
    22621 gtattggcgg tggttatgca atcatacctt taatccaaga gaaagtagta aatcaaactg
    22681 gatggataag tgagaaaatg tttacagata ttataactat ttcacaaatg acaccagggc
    22741 cactggctgt taatacttct acttttgttg gacttcaaat tggagggttt tggggagcag
    22801 tttcagccac tttaggttgt gtattatgtg gtgtagtaat atctctattt ttatataatt
    22861 tttttcaaaa gcatcagaac tctacttata tatttgaaat attaaatggt ctaaaatcag
    22921 cttcattagg tttaattatc tcagctgcgg ctacaattat aatccttgca ttatttggga
    22981 cgaataaagt gtacttcaat tctatatttg agatgctaaa ctggactgca ctaataatct
    23041 tttttgttac actactgata gtacgtaagt ggaaaattaa tcctattgtg attataataa
    23101 taagtggtat actgggaata tttttttatt tataagtttt tggtaagtaa aggatatcta
    23161 tttttttata tcttaaatcc aaatagccaa taaagtaagg ctatttggat ttttaataaa
    23221 ttctgaaaag ataataagaa acccatataa catttaaatt atatcactgg ttttctataa
    23281 accaatcata agcttcttgg caaaatttct cactatctat atagtaacta ttatgaacat
    23341 tattaatttc aacaagtttc tttttacatt ttagtgaatt ataatagcta tcaaaatatt
    23401 gggttttaaa atatctatca tgaagtgttt taaagacaag agtaggtatg ttgactccat
    23461 cttttatctt actatctttt gcaataaagc attctaacat tgtattaatt atctttgtac
    23521 tatttttcca aatattttat aaaattcatt atcatagact tcattataac ctttatattt
    23581 aggtggtttt actgttatgt gaaaattagg aagaaactta aagaaaaagt ttaataattt
    23641 ttatgttctg ttttatatat tattcatatt ttatcacaga taatatacta aagttaattt
    23701 ttttattgta caactattat aataattctt ctataatata agacattcta taattttata
    23761 tttaagttca tgtgtattta attgttttta tataaaatgt ccagtaatac tatttggatt
    23821 tatttttatt tcatcaggag ttccagaagc aacaatttcc cctccattta ttccactgtc
    23881 tggacctata tcgataatcc aatcagaagc acgtataacc tctgtattgt gttcaataat
    23941 taaaagtgaa tgctgttcat ttacaagttt tctaaaagta attaacaaat tttctatatc
    24001 tttaaaatga agtccagtag taggctcatc caatatgtac agcattcgtt ttttagtttt
    24061 tgtccctaat tcttttgcta attttatcct ttgagattct cctccactta atcctaatgt
    24121 attttgtcca agctttagat atccaagtcc cacttcatct aataaggaga gttttctata
    24181 tatatcagag caatcgctaa aaaatgtttt tgcttctgct acttccatgt caagtatatc
    24241 tgcaattgtc tttcccttgt attgtataga cagtatttct ttttgatatc tcttaccttg
    24301 acattcacta caagttaccc attggtctgc catatattgc agaataattt ttgttttacc
    24361 taatccttga cagtttgggc attgcccctt tttgctatta aagctaaaat agctttcatc
    24421 caataatttt tgttttgctt gtggagtttc agcaaataga gaacgaattt catcaaaaat
    24481 attgatatat gtagcaggtg tagaacggct agattttcca ataggtgttt ggtccattaa
    24541 gataaaatca tcaatagcat caaatccagt aaattcagta taatttttat ctgggataga
    24601 tttttgtttc aatttttctt ctagagcagg aagtaaactg tgaaatacaa gagagctctt
    24661 accagaacca ctaacacctg taatagagca catacagttt aagggaattt ctacatcaat
    24721 attttttaag ttatttgcat ggcatccttt taagcttaac catttacttg gtatagtttt
    24781 attttgtgaa cctgttttat tgtatgtact taaatattta cctgttatag agtttggatt
    24841 ttttataatt tcttgggttg taccttctgc aataatgaac cccccttttg taccagcact
    24901 tgggcctaca tcaataatat aatcagcaga cagtattgta tctttatcat gttccacaac
    24961 tataacagta ttacccttat ctcttagttc ttctatcatt ttgatgatta aattatggtc
    25021 tcttgggtgt aaaccaatag atggttcatc taaaatgtat gttaagccta ctaattcact
    25081 tcctagctga cttgataatc gtactctctg cagttctcct ccagataaag ttggagctgt
    25141 tctatctgtt gatatatagc taagacctac ctttaataga taactaactc gaatttttaa
    25201 ttctgttaag atatcattta ccaaagagag ctcatttttt tgaagttgat ttggtaattc
    25261 acacaaccaa ttccataact gttctatcgt catttttgtt agttcaggga agcgataacc
    25321 tttgattgta gtgaatctag cctcaatgca cagcaattcg ccaccacatg tattgcaagg
    25381 aattttgttc atatattgat gcaaggtatt attttcagaa ctagattctc taaaaagtct
    25441 ttgaatgtgg ttgattgctc ctgaagcagg tcttctaatc tttgattctc gtccctttga
    25501 ttcaaagcta aattcatata tcttatcgtc tgtaccatat aagattgcat ctataaaatc
    25561 tcttggtaat tcattccaag gtatatctag gtctatattt ttatcttttg ctattgcata
    25621 taattcacct accatccaat taccatttgg ctttttcccc ctcaattttc caaaatagta
    25681 agtagctcca tctaatattg aaatagttgg gtcttttaca attaattgag gattaacttg
    25741 ataggtaaaa cctaatccat tacaatcgtg acaagctcca gtatgggagt tagcattgaa
    25801 ggttgaagta tttatcttag aaaaaatagt ttgacaatgt ggacaataat tttttgtatt
    25861 attctttttt tctaatggaa ttttgcaata tggacagtaa ctttttccga ttgatacaaa
    25921 taacattctt aaataatccc aaatgcttgt aagagtacca acagtagagc gaggattttg
    25981 gcttcctttt ttctgttcga tagctatagt aggggttaat ccctgaagta aatcaaattc
    26041 cggtttttga agctgttctg aaagttttgc tccattactt agattttcaa aataacgtct
    26101 ttttccttct tcataaatcg tatcgaaagc taaagaagat tttccactac cacttacacc
    26161 tgtaataaca gttatttgat tttttggaat tgtaacctca acatccttta aattgttttg
    26221 ccttcctcct tttaaataga tagagctttt attatgacaa agtgaatttt taattgattt
    26281 atttattgat tttgtaaatt tgaatttctt ttctagttca agaggattgc ctaattcttt
    26341 tatttccgaa atacctaata tttttaactg agaaaagatt gatttcaaat aatcttcagg
    26401 caatttttct attaacaaat taaggtcttc tatttttata tttccgcttg ataatatctc
    26461 tgccatttca tctaataaat ttttttctgc tcttgttaat tgattgtatt ttttggaact
    26521 taattctgtc cataaatccc atggaagcaa ttctaaacca atcatattat taaagtcatg
    26581 tagaagatta ccctttacag aatgccaacc tttccaattt ttattatatc caaagtcatc
    26641 tggatgagca tgtccttgcc gacatcttat ccaggcttct gaaccagtta aaaaaccatc
    26701 tgtttttccg acatcatgag tgtcaaaatt aatttgaaaa taattttttt gtatgtcatc
    26761 tatttgtgca tctattctta tccatctctt tgttagagta tcatagtatt ctacaagcca
    26821 gtggtcttca taagtaagct cactttcaaa ataattagca aaacctgctc tcattctagc
    26881 ctcaaaacct cgatatctta ggagcgatac aagaagtaaa gaataatctc tacacattcc
    26941 aacaagcctt tgttttgggt ttcttggaat agttagtggg ttagaattta tttcaaatat
    27001 tctttttaac atttgaggaa ttgtacgaag caattcctca tcagattgtt gcttattaaa
    27061 ggatatacca tataattttc cttggtctcc atgaattact aggctttgaa ccacttttaa
    27121 taactcaatt ggagtctttg gtaaatcttg atatttattt tcaaattttt taggatttgt
    27181 gatgatgctt tgatttttat agttatttat tttcatttat atttcacctc tctaaatgga
    27241 tgatataccc tgacatggtg tcatatgcaa ggacaattta gattttttgg ccaaaattta
    27301 aaaataaata aaaaatgata cagtgataaa ttgtaataca aatatagttt caaattgcat
    27361 ataatataat tatttaataa aaccattatc tatggaatgt taatgaaatg ttaagatggc
    27421 attcttgaat attaagaaat agaatactat aatatagtgt gaaggattct tagtaaaaaa
    27481 atttgtaagt gttaatatac attaaaaaat aggtttataa tttggaggaa aaaaatgaaa
    27541 ttatcaaggt ataagaaaaa tagtttagtt ctgtctataa ttttatgttc acttattatt
    27601 tcaatccttg taattactgt ttttaatacc gtaaaactac acaatatatc taataaacaa
    27661 tctaaaaact atttaaacga tgtatctaca cagattgtaa tgaatgttga ttctaaaatc
    27721 aaatttattt tatccgactt aagaataatg gcagatttta ttaagcaata tgaaggtgat
    27781 agtcgatatg agtatttatc taaaagaaag actagttata agtattatga tgttggaata
    27841 atagatttag aaggtaaagc tgagttttta agtggaaaaa agtttgactt aaagaatact
    27901 gcttcctata aaaaaggaat tgaaggtaaa gaatactcag aagtaataga gtcaatgggt
    27961 tttgttcttt atagtgtacc tatatttaat gataatcatg aagtatctag tattttaata
    28021 ggtgtatcca ataaagaaag tatgaatgag attcttaata tagataactt taatggagaa
    28081 ggaactattg aaattattaa tagtaaggga aaacctcttt tcataggaaa aaatactgag
    28141 ttaataaaag accttagcca taaatataag gattctgcag atgaactttg ggcacaaaag
    28201 atgcttaatg attttaaaaa tgataaatca gggaatatta caataacctc atcaaaagga
    28261 gtacaatgct tattaacgta tcatccaatt acaagaggtt taaatgattg gcactttctt
    28321 ctcatagtac ctgaagatgc tgtacttggt gaacttaata agttaaattc ttttacaata
    28381 acaatgacat ttataattac atgtattatt ggaattataa cattaatttt atatatcata
    28441 agaagaaaat atgtaaatca aatagaaaat attgcatatt tagatagtat aacaaatggc
    28501 ataaattcaa ctaagtttag tatgctagtc aaacctttaa tttcagaatc acctgatagt
    28561 acttatatga tgatagcaat gaatataaaa gattttaagc taataaatga ttgtttcggt
    28621 agtgaaaagg gaaatatgac actaaaacat ctttacaatg ttttgtataa aaacattgat
    28681 gaaaatgaag aatttgtgtg ccgtcatgat gcagaccttt tctatttgct tattaagaat
    28741 agaccagtgt tagaagccct ggagttatta tataaaatag aagatgacac aaattatttt
    28801 aataaaaata gggaaaatcc atacttttta agactatccg taggtattta cacaattgaa
    28861 aatcataatg aagatttaat tacaatacaa gaccatgcaa atacagcaag aaaaagcttt
    28921 aataaaactc atcaaagtga tttttctttt tatagtgata tagaaagaaa acgattaata
    28981 tctgaaaagg aaatttcaaa tttaatggaa aaagcccttg aaaataaaga attttttatg
    29041 tgcttacaac ccaaaattga tataaaaagt ggaaaaatta gtggagcaga gtctcttgtg
    29101 cgttggaaaa attcagaaaa gggcataatt tatccaagtg attttattcc tcttttcgaa
    29161 aaaagtggat ttatatgtaa gttagattta tatatactag aagaaacatg caaattgatt
    29221 tctaagtgga taaaagaagg taaagaagtg ttgagaattt ctgttaatgt atcacgtcaa
    29281 catctgaatg ataaattgtt tttagaaaaa tataagcata tatgcaataa atacaatgta
    29341 ccaacatgtc tgatagattt agaacttact gaatctattt tcttagaaaa tccagaagct
    29401 atagatataa tagaggatat tcattctaat ggatttaaat gttctataga cgattttgga
    29461 tttgggtact catcattagg gatattaaag gattttaaag ttgatataat taagttagac
    29521 cgttcattct ttgttagcaa aaataatata gaccgtggta aggtagttat taagtctatt
    29581 attgaactta gcaaaaggct aggtatgaaa gtaacagctg aaggaattga agaattagaa
    29641 caagttgagt tcctaaaaaa tgtgggatgt gattatattc aaggttatgt tttttcaaaa
    29701 ccattattaa tttctgactt tgaaaatttt gcatatgaaa ataataaaat taaaaatatc
    29761 cattattaaa tgtacaagat aaaaaattta ggcaagttat ataattaaaa atataacttg
    29821 tcttttttat ttatatattt aataaaaata tatttgcaga ttttgtaaaa ataattttca
    29881 aatgttgtaa gttgtggcta aagctttatt gtattattct gaatatagaa agataattac
    29941 tgtcttagat aaaaactgaa acatacataa taatataaaa tttgctatat taataactct
    30001 aattattttg gaaggaggga aaatatgata agtgggagaa tgttactcat catgaatttt
    30061 ctaaaaggaa aaaataagac aagttacaag gatattagca aacaacttag tatagaagaa
    30121 agaaaagtta gatatgatat aaataattta aatattgttt tgcgttcatt aaacaagtca
    30181 gtaatacaaa agatgaacaa aggtgtatta attattcctg atgacttcca agtagtatgt
    30241 ataaataata acgaatatgt attttcctta actgagcgag tatctattat gaaaattata
    30301 tcaatgttta aaatagataa tctaaactta gaaaaattaa gtaaagaatt tcaggtttct
    30361 agaagttcaa ttaaaaatga ccttaatgtt ttgtcaagtg aattagaaag aaaccaaata
    30421 actattactt atgataaagc ttttaaaata agtggagaag aagacattat atataagcaa
    30481 agattgaaca tattaaaatc gtattcttat ctttttggta aggaaaaatc tgatttaagt
    30541 gtatttgaga agtatttagt aaatgtaatt gaaaaaatat tcaaagggat ttatttaatt
    30601 gatatatata attggtctat gaatttatta ttgcaaatgg gatggacttt aaatgatgaa
    30661 tcttttacat ggtatgtgtc aaacattttc ctttttacat ggtatataca ttcagatgaa
    30721 aaacatcctt tagaatctgc ttcattaagt gagccgtgtt ttgaaaataa gtttgaccaa
    30781 gaatttgaaa caattattca aaaaaagttg actaaggaac aaatttttct gttaaagagt
    30841 tttgtatttt ttacaaataa atatgcaagt ttaaacgagg atatggattt gattagtaca
    30901 gaaattatag ttcaagacct aatttacaat atgtcagaaa tattagagat tagctttaaa
    30961 gaagatatga ttctttataa aggattactc aatcatattg ccccattgat agagagaatc
    31021 aagcagaata tacagattta tgaggaatta cttcatgtaa taccagataa atatcaatat
    31081 gtacttgaag ctactaaggt ttctattcaa aaaaacagag ttttaagtca aataaagaat
    31141 gaaaatgaaa caatactttt ggcaatacat ttcttaggaa gtatacatag aaatgagagg
    31201 aataactaca aaaatatatt gttagtttgt ggatttggat atggtgtaat tgctatgtta
    31261 aaggatagtt tagtaaatga ttaccagata aatatagtag agagtattcc atcatataag
    31321 ttacaagatt ataaagactg ggaaagtatt gacttcatta taacaacatc aaagatagta
    31381 atagacttgc ctaaaacaat tattgagata aatccatttt tacaagaaga ggattatttg
    31441 aagtttgaag aaaaagggat aaaaagaaag aacgtcttaa ctaattatat gtcaataaaa
    31501 aaaaggttgg actttttaga agaagatgcc caaaaaagag tattaagtat tatatgtcaa
    31561 gaacttggat acagtgatga gagaatatta tttagacaac ttaatttaag tgatttaata
    31621 gggattgata ccataaggat aattgatgga gatatgaaat gggaagatgc tgtaaaattt
    31681 agttcaaaca tacttgctaa ttgtgatttt gtatcagcac aatatgctga gaatattata
    31741 gatattttaa aaaatgtggg tttttatgct gtaaaagata acgaatttgc tttactacat
    31801 ggcaatgata gttcattagt caaagtaagt tcgataagtt tattaatatg taaagaagca
    31861 gttagttttg gagataaaaa ggttaaaatc atattttgcc tagcaagcag agataaaaaa
    31921 gagcaaattc ctgcaataat taatctaact aaaatggttt ataagactaa ttttattgct
    31981 atgttagaaa gtgcaaagac aaaagaagaa gcagaagttt taattcataa atatgagaag
    32041 gaggtcactg tatgaataaa ttagttaatg taaaatgttc atttaaaata catgttaatt
    32101 caaaagaaga agccattata tcgttagttg atgtagtgtc aaaagaagga tatttaatag
    32161 ataaaaatca atttttaaaa gatgttttaa agagagaaga aacattgtcg acttatattg
    32221 gacatggtat aggtcttcct catagtcaaa gtgtaggtgt taaaaactct tgtattacaa
    32281 taggaaagct tgatactcct attgaatgga cagaagaagg agaaaaagtg gatttaatat
    32341 ttttgatatc agtaacaaaa gacaatgaaa ataatcttca tttaaagatt ttatcaaaat
    32401 tagcacgttt attgatgcat gaaagtttta gaaatcaaat tagatgttca gatgaacaaa
    32461 ctgtttataa tcttataaaa gaaaaaatag aggaggaaga ttaaaatgag aattttaaag
    32521 tttttgcaaa aacatcttat gacagcaaca tcttatatga ttccatttgt ggttgcagga
    32581 ggaatattat ttgctttatc agtaacttta agtggacaag ctgctgttcc tgaaacaggc
    32641 tggttggcta aactgaatca aattggagct gctggcttgg ctttattcat tcctatatta
    32701 ggtggatata tagcatttag tatggcagat aaaccaggat tagctccagg tatgataggt
    32761 gcatatttag caaaagaagt aaatgcaggt tttataggtg gtatcatagc aggatttata
    32821 gcaggatttg ttgttttaca attaaagaaa attaaattag ctcctacaat gagaacttta
    32881 ggttctatat ttatttatcc tttgattggt acattgatta caggtggtat aattgtattt
    32941 ttaattggag aacctatagc ttcttttatg acatggatga caaactggtt aaatggaatg
    33001 tctggtgttt ctaaaattcc tttaggtgga atcttaggag gaatgatagc ctcagatatg
    33061 ggtggtccta taaataaggt tgctgctact tttgcccaaa ctcaagttga cacacttcca
    33121 tatttaatgg gtggagttgg cgttgcaatt tgtatacctc caattggttt aggattagct
    33181 acattattgt ttccaaaaaa atttagcaag gaagaaagag attcaggtaa agcttcacta
    33241 ttaatgggat gtgttggaat tacagaagga gctattccat ttgcaacatc agatccagtt
    33301 agagtaatac cttgtattat ggctgggtcg attgtaggaa atattatggc ttttttatta
    33361 ggatgtttaa atcatgcacc ctggggaggc ctgatagtat tacctgtagt tgacaatagg
    33421 ttggggtata ttgcatcagt attaactgga gcagtagttg ttgcagtatt aatgaaatta
    33481 gtaaaaaaag acgtgaaaga agatgaagaa attgaagaag atttagatga atcaattgaa
    33541 ttaatatttg aagaattata aatataaatg gaaggaattt gtataaaaaa gtaaatataa
    33601 aactataaat tcaaaggaga taagaatatg aaaattgtag cagtaacatc ttgtcctagt
    33661 ggagtagcac atacttacat gtcggctgaa tcacttgaat tatcagccaa aaaatttagt
    33721 atagaaataa aggttgagac tcaaggaagc tctggaatag ataatgaatt gtcacttaaa
    33781 gatattgatg aagcaacttg tgtaatattg actaatgatg ttgagattag aaatattgaa
    33841 cgttttaagg gaaagaaggt agtaagaatg agtgtatctg agataattaa gaaatctgat
    33901 gcattaatta agaaaataaa agatactttt caataaaaat tgatttattt tacatataac
    33961 tcaaagatgt ttttaaagaa atttttatta aaagcatctt tgaaaatatc ttaaaaatag
    34021 aataaaagga gatatagtca tgaaaaagtt accaataaag actgtcgtac aaagattact
    34081 aaacttacaa gaagagggga aaagtgcaac tcttttagga attggtccta tgtcaccaaa
    34141 cttgttacaa gcaagttttg aactagcaaa agatgatgat tttcctttaa tgtttatcgc
    34201 aagtagaaat caagtagatg cagatgaact aggtggcggt tatgtaaatg gttggaatca
    34261 ggaaactttt acaaaagata ttaagaaggt tgccgacaaa gttggatttg atggtttata
    34321 ttatttatgt agagaccatg gtgggccatg gcaaagagat aaagagagaa atgaccattt
    34381 gcctgttgat gaagcaatgg agttaggaaa aaaatcttat ttagcagaca ttgaagcagg
    34441 ttttgaccta ttgatgattg accctacaaa agacccattt gaaattggaa aagtaattcc
    34501 actagatgta gtactagaaa gaactgtaga attaattgag tattgtgaaa acgagagaaa
    34561 aagacttaat ctaccagaca taggttatga ggttggtaca gaggaaacca atggaggtct
    34621 gacttcaact gagacgtatg aaacatttat aactagacta aaggttgaac ttgataatag
    34681 aggtttgcca atgccaacat ttatagttgg tcaaactggt actttaacta gaaagacaga
    34741 acaagtagga acttttaatt ttagaaatgc ttatgattta gctcaaatgg ctaagaaata
    34801 tggagttggt ttaaaagagc ataatggcga ttacttagat gatgtaactt tattagaaca
    34861 tataccatct caaattattg ctacaaatgt agctcctcaa tatggtactg aagaaactag
    34921 ggcatattta aaattagcag aagttgaatg taaattagaa aaagagggcc tagttgataa
    34981 aacttctaat atcagacatg ttcttcttgt taatgcaatt gaatgtggac gttggagaaa
    35041 atgggtagta ggagaacaaa aaaatctaac tacggaagag atatttaaga atgaagtttt
    35101 atctaatgaa atactagata ttgcaggaca ttatacattt aataatgatg atgttaaaaa
    35161 agaaatagaa gtgctttatg ataatttaag taagaataat attgatggtc aaagatttgt
    35221 tgtagactat attaaacgtc ctttgcgtga ttatgcagaa tgctataact taaaaggtgt
    35281 tactacgagg attttaaata aataatagga cttatagtgg tgagtattgt tatactaggt
    35341 atttatagtt ataattatac ttaccactat taaatttagg aggactaata ttttgatcaa
    35401 tttaattttt gatgtagatg atactttata taatcaatta acgccttttt acactgcata
    35461 taataaagtg ttttcttcaa taaaggatat ttctattgaa gatttatata tgagtagtag
    35521 aaagtatagt gatgaggtat ttcatatgac tgaaaatgga gaaatgccaa tcaaagaaat
    35581 gcatatttat aggataatga aagcttttga ggagttggga aattctatta cagaaaaaga
    35641 tgcacaaagt tttcaagatg agtatatata tcaacaatca caaattacac taataccaga
    35701 agttgagagg attttaaatt tttctaaaga aagaaatatt aatctaggaa ttataactaa
    35761 tggcccatca aaccatcaaa gaatgaagtt aaagcagtta aatattgaaa actgggttga
    35821 taaaagtaat atttttattt ctagtgaggt tggattttct aagccagata ctaatatttt
    35881 tagagtagct gagaatgtta tgaatttaga tagagaaaat acatattatg tgggtgattc
    35941 ttatagaaat gatgtattag gtgctaaaaa agctggttgg aagagtatat ggttgaacca
    36001 tagaggacat gaggtagaag agttgtttta taaacctgat tttgtaattt tggaacataa
    36061 ggatttgata tctttattta taagaatatg tagttataaa aatatgtagt aaaaaaatgt
    36121 taataataga attgtataaa ataattaata ataactatat aaaattatat gtttagattg
    36181 tgagcaatct attttatgtt aaaaatagat tatttagaag aaggggaaat cttaaaaaaa
    36241 tttgaatatc ccctttttat tatttaatta aaatgaaata gttagaaata tattttattt
    36301 agtttagtca ataacatttt gggattcttt ataactacat gttaactgtt gaataggttt
    36361 atcatatggt ttaacccatc ctttattaat acttaattct gtaagtgctg tgtgaccttc
    36421 taccatttga gttaatgaag ctgaatatat agctcttagt tcaggtgtac tacttgtcaa
    36481 tgcagaatta agatacatat tggcagatgc tttagcagat gaaagcatac ttaacattat
    36541 tactttatcg tctatataag tattgttctt aattagattt tctatcatat ttctcatgtt
    36601 atctatacct cctcagaaat tagtatttca ttttcaacta taaattgttg tatagcttta
    36661 attcttcctt ctgttgctaa tatactagat tctgattgtc tttttagatc ttcatctgat
    36721 attaacatat ttattgctct ttgcataagt aatccgtcag actccatttt tataattgct
    36781 gctaaagata ttttttcagt ttctgaaagt attctcattt aatcatctcc tatattgtaa
    36841 tttatgcttt aatagtatgt ctttcttttc aaggaaataa ccattacact tttttacagt
    36901 attttatatt ctcgttatat caaaatttag tcgacttaat atattaatat aattttgtag
    36961 gatatttatc attaaatatc tataaaataa attgtttgaa tattcataaa gcaaaattta
    37021 tttgtatgta cttcttcaag agtaaatatg agttttttca aaaaattaat ttttatgata
    37081 attattaagg gctatatttt tcttaaagtt gtgattatca ttattaattt acaataaaat
    37141 tgccgaaaag ccctctcctt taggtgtagg gatgaaaggt aaggtcttaa tataaaaaag
    37201 ttagaataat gcttgtaatc taataccgct attgataccc tatatttagg aggtgttagt
    37261 ttttatgtat aaatctaaca aaaatatagt ttatgattgc aaatatcata ttgtattttg
    37321 ccctaagtat cgtaaacctg ttttagttgg cgaagttgaa aagatgttaa aagaaatact
    37381 accatataaa gcagatgaac ttggagcaga aataatagaa atggaaactg ataaagaaca
    37441 tgtgcactta ttaatatctt gtgaccctca atatggaatt cataaagtag taaaaggttt
    37501 aaaaggcttt agttcgagag tattaagaga gaactttcca catttaaagt ctagtatgcc
    37561 tagcatgtgg actaatagct attttgtagg tactgttggt tctgtgagtt tagaagtagt
    37621 taaacaatat atagaaaatc aacaagttag gacaaagaaa tgataaaaac tcatagagtg
    37681 aaattaaacc taactagaac acaatttgaa ttagtaaggg aaaagcaaat ggaaagtgct
    37741 aactgttgga actacatagt taacttatct aaagaatact attttgaaca taaacaatgg
    37801 attaaaaaga atgatataca aaagttaatc aaaggtaagt acaatcttca tagtcaaact
    37861 attcaagcta tatcagataa atttgatgca aatagaaaga ctatatcaga attaagaaaa
    37921 aaaggtaata ctaaagcaaa atatccatac aagactaaga aattttatat aatacctttt
    37981 aaagctagtg ctattaatag aaatgctaaa ggcaacttaa aattatcaat gtcaaaaggc
    38041 aggtatttag aattagattt taatgttgag aatataaaaa ctgctgaaat agtatggcga
    38101 aatggatatt atttatacta cacttttgac aatgaattaa atggagttgt agccaaaggc
    38161 actaataccg taggtgtaga cttaggggaa atacattcga tagctagtgt aacaaataaa
    38221 ggtgtagggc ttattctatc taatagagaa ggcagaagta ttaaacaatt tagaaataag
    38281 atgtatgctt atatatctaa aagattaagt aaatgtaaaa aaggtagtag acaatcaaag
    38341 aagttatgga gattaaaaaa taagataaga agtaaaacag ataatcagtt aatgaattta
    38401 tatcatcaaa caactagaaa gtttatagac ttttgtgtag agcagaaggt atgtgaaata
    38461 gttcttgggg atataaaagg ggttgaaaaa gatactaaga aaaagaaaag attaaacaga
    38521 gttaatagac agaaaatatc tcaaatggag tatggtcgaa taaaggacta tataaaatat
    38581 aaagcaaaag agcaaggtat tgaagttaag ttagttaaag aaaactacac ttctcaaact
    38641 tgcccaaagt gttctaaaaa acacaaacca actggtagaa cttatagttg tacttgtggt
    38701 tatgaaactc atagagatat agttggtgct tggaatattt taaataaaaa gcataaatat
    38761 ggtttagtag attttagaat aaatcataag caaccaataa atttaaaagt atctaccgtt
    38821 tgagccatgt gtgggcgaat aactttaagg tagtagtggc gaagacaccg tccgaagtag
    38881 cttggctttg taaccacctc tgttgtactg tttaagtata aataagtgtg ttagccacca
    38941 agaatcccct tgctttagct atggggagtg tgtcaataaa atactttaat gaaaaatagc
    39001 taactttaat tgtaggatat tcttaatata tttgaaataa ataaaaatat tgaaggatat
    39061 aatattcaat tggtatataa ataataaatg atagttaaat tttaccttag aggctaatta
    39121 ggtgtttagt caaagctaat gcctttagaa tacaaatgta ttctaaaggc atttttacta
    39181 tgtattttca tttatattac taaacattat ctatttttat atacatttct atgtatttta
    39241 ttttcatcaa atcggtctat aaactcattt ttttcttcac tatatccaat agatataagt
    39301 gcataaggaa ctaattttaa tggtaagtct aaagtttgtc taactttatt taccacttta
    39361 tttttaggaa atactcctgc ccaacaagca gctagacctt gattagtaac ttctaataat
    39421 aaattttgtg tgcaagcacc taaatcttgt atccatttac caggttttaa gaatttatct
    39481 ctatttccaa gcactactat acataatggt gcaaattcta tatgctttgc tctatgctgt
    39541 gactttgaga gctctttcag cagttcctta tcatctacta taataaattc ccaaggttga
    39601 gcattttttg atgaaggtgc ttgcatagct gattttagta tttcagttat tttatcttct
    39661 tctatatttt tatctatata tgttcttatt gaacgtctat tttttataac ttctaacata
    39721 cagattctcc tttaaataaa attatttcta tttatataat atcattactt taaattttag
    39781 ctattactta tataaagaat aaactttgtg ttggttttat ctaagtaaaa gtaacattca
    39841 gaactaaaaa acaagactat aaatccaaag tattaattaa aaaagaagta ataaaaaata
    39901 atatacaaga tttaaaaaag agtatagggc ttaaaattta attagaaaac caattttgag
    39961 ataatctgtt ttttatttta acaaaaaaac ataaataaag ttcgatacgt agcgaatgaa
    40021 aaaattacaa gaaatatttt ttttaaaaaa tttcaaaaaa gagttgataa tatatgtata
    40081 ttaatataaa atttaaggtg tataattcgt ataataatac gaatgatttg tagtgtaaaa
    40141 taacttataa acggagaggg gaagtctaat gaaagtagca gtagttatgg gttcaaaatc
    40201 agattatcca aaattagaag aagggataaa actgcttgaa aaatatggaa tagaagttgt
    40261 agcaagagca ttatcagctc atagaacacc agaacaactt tcaatattcc taaaagaaat
    40321 agaagatgat attgatgtaa taatagcagc agcaggaaaa gcagcacact taccaggtgt
    40381 aatagcttca caaacattaa ttcctgtaat aggattacct attaaatcat caactatgga
    40441 tggactagac tcacttttat caatagttca aatgccaaaa ggaatcccag ttgcaacagt
    40501 tacaatagac ttaggtttaa acgcagcttt attggcatta caaataatga ctttaaaata
    40561 cccaaaatta aaagaggatt tgaaatcata tagagaagag atggcacaaa aggtgttaga
    40621 agacgacaag aatttaaggg ggtagcagaa atgttattat atgaaggaaa agcaaaacaa
    40681 gtatattcta cagataatga aaatgaatat gttgtttatt ataaagatga tgcaacagca
    40741 tttaatggag aaaaaaaagc agaaatatct tcaaaaggta tactaaataa taagatatca
    40801 acaataatct ttgaaatgtt aaaagaaaat aatataaata ctcactttat aaaaagttta
    40861 tcagatagag aaatgttagt taaaaaagta gagattttac cattagaagt aatagtaaga
    40921 aatattgctg ctggttctat ctgtaaaaga gttggtcttg aagaaggtgt agttttcgat
    40981 gagccaattt ttgaaataag ctacaaaaat gatgcttatg gtgacccaat gctaaatgat
    41041 gattatgcag tggcaatgaa gttagcaact agagaagagt taaaattctt aagagaagaa
    41101 actttaaaaa taaatgagtt actaaaagca tttttcttaa aattaaacct aaagttagtt
    41161 gactttaaaa tagaatttgg taaggattct gaaggaaata taatattggc agatgaagta
    41221 tcaccagaca cttgtagact ttgggatgta aatacaaatg aaaagttaga taaggacaga
    41281 tttagaaaag accttggaga ccttgtagaa ggttatacgg aagtactttc aagaatgaat
    41341 aataaatagg aggcaaatgt atgtgtggag ttttagggat ttactctaat aaagatgtaa
    41401 ctaaagaact atattattct ttatattcta tgcaacacag ggggcaagaa agctgtggtt
    41461 tagctctttt agatgatgga gaaattaagt acaaaaaaga tatgggatta gttggggatg
    41521 tttttaagga aaatgaatta tctaagttaa aaggaaatat agggattgga catgttagat
    41581 attcaacagc tggaggaagt catgtttcta attgtcaacc tttagttgga agttgtagaa
    41641 aaagacaatt agccatagct cataatggaa atctagttaa tgcaaattat ttaaaagata
    41701 tgctagaaga agatggatat atgttccaaa ctaattcaga tacagaagtg attttatata
    41761 tacttgctag atattacaaa ggggatatag tagaaagttt aaaagtgaca atggattata
    41821 taaaaggtgc atatgctctt gtaataatga gtcaagaaga attggttgca gttagagacc
    41881 cacatggatt cagacctctt gtacttggta aaaagggtga tgaatatata tttgcatcag
    41941 aaaattgtgc aatagatata cttggcggag aagttataag agatgtagag ccaggagaga
    42001 taatagtagt caaagatgga gaactaaaat catattttta ttcagaaaat tataaaccag
    42061 ttaagaaaag ttgtatattt gaacacatat actttgcaag aaatgatgca actatagaca
    42121 atgtaaatgc atatgaattt agaattaaat gtggtgagag attagctcag aatgaaactg
    42181 taaaggcaga catggtagtt ccagttccag attcaggttg gccaggagct attggttatg
    42241 caaatgctag tggattaaaa ataagtgaag gcttagttaa aaatagatat gtaggaagaa
    42301 catttataaa acctacacaa gaagaaagag aaatagcagt aaaaataaaa ttaaatcctc
    42361 tttcaacaat aataaaagga aaatctataa ttttagtaga cgactcaatt gtaagaggaa
    42421 ctacatctaa acagttagta aaatctttaa gagaagcagg agcaaaagaa attcatctta
    42481 gaataacttc tcctccagta gcttactctt gttactatgg aatagatact ccaaatcgct
    42541 ctaaattaat tgcatcaagt aacaacgtag aagaaatgag agaatatatt ggatgtgata
    42601 gtttaaaatt cctagatata gaaggaatgt tagatgcaac agaacataag tctactttct
    42661 gtaaagcttg ttttgatgga gaatacccag ttaagaaaat tgataaggag gaactacttt
    42721 catgttaaca tataaagaat caggtgtaga tatagatgaa ggaaatagag cagtagacct
    42781 tataaaaggt aaaataaaag gaacttatga tggaaatgta gttggagatt taggtaactt
    42841 cagtggatta tacagtttaa aagattttgt aggtatgaaa gaaccagttt tgcttgcatc
    42901 tacagatggt gttgggacta agttaaaaat agctcagatg atggacaagc atgatactgt
    42961 tggaatagat ttagttgcaa tgtgcgtgaa tgatttaatt tgtcaaggag caaaaccatt
    43021 attcttcctt gactatatag ctcttgggaa attagtgcct gagcatatag aaaaaatagt
    43081 tggtggaatt gcagatggtt gtaaaatgtc tggttgtgca ctaattggtg gagaaactgc
    43141 tgaaatgcct ggaatgtatg gagaagatga ctatgattta gcaggatttt ctgtgggaat
    43201 agcagacaaa gaaaagattg tttctggaaa caatgttaaa tcaggagatg tattggttgg
    43261 tatatcttca agtggagtac acagcaatgg attttctttt ataagaaaga tatttttaga
    43321 aacttacaat tataaaatgg aacaatatgt tgaagaacta ggaatgacag ttggagaagc
    43381 acttttaaca ccaactaaaa tatatgttaa attagcttta gatgtattag ctaaacatga
    43441 cataaaagct atagctcaca taactggtgg agggcttata gaaaatataa caagagttat
    43501 acctaaaggg ttaggactag atatcaataa aaaatcttgg gagaagcctc ctatatttaa
    43561 aatgatagaa ggttttaatg ctgttgatga gagagaactt cataagagtt ttaacatggg
    43621 tattgggcta gttttaatag tagataaaga aaatgctgat gatgttgtaa actttataaa
    43681 taatagagaa aatgacaatg ctgcttatgt agataaaaaa tatagtgaat tattagaaga
    43741 taaagcgtat ataattggtg aagtagtaga tagtcatgaa ggtgtagaat tatgctaaat
    43801 ataggagttt taatatctgg tggaggaaca aatttacaag cagttataga tggtactgag
    43861 tctggagaaa taaaaggtca ggttaaagta gttatctcaa gtaagcaagg tgcttatggt
    43921 ctagagagag ctaaaaatca taacataaaa gcaatttgtg aaactgatga agacaagata
    43981 atagaaattc ttaaggaaaa taaaatagat ttagtagttt tggctggtta tttaaaaata
    44041 atcagcccaa agctggttaa tgagtttaga aacaaaatga taaacataca tccatcatta
    44101 attccttcat tttgtggagc tggattctat ggagaaaaag ttcatcaagg tgttatagat
    44161 tacggagcta aagtaactgg tgctacagtt cattttgtag atgaaggtgc tgatactgga
    44221 ccaatcataa tgcaagatgt agttaaggta aatcaagatg atgatgcaaa gacacttgca
    44281 aaaagagtgt tagaagttga acataggatt ttaaaagaaa gtataagtct tttttgtgaa
    44341 aataaattaa aacttcaagg taggagagtg tttataaatg agtaagagag ctttaataag
    44401 tgtaactgac aagactggtg tagtggaatt tgctaaagag ttaaataaat tagattatga
    44461 aattatatct acaggaaata catttaaaac attaaaagaa aatggtgtta atgtaatgca
    44521 agttgaagat gttacaaatt ttccagaaat attagatgga agagtaaaaa cattaaatcc
    44581 atatatacat ggtggtatac tttataaaag agataaagaa tctcatgtag aaactgtaaa
    44641 tgaacacaaa atacattcaa tagatttagt agctgtaaat ctatatgatt ttgaaggaac
    44701 tttaaaagct ggaaaaagtc atgatgaaat aattgaaaat atagatattg gtggaccatc
    44761 tatgatacgt tctgctgcca aaaactataa ggatgtaata gtagtagtag atataaaaga
    44821 ttatgattct ataatagaaa aattaaaaac agatacaatg acattagaag acagaaaaaa
    44881 attatcatat aaagctttct caactacagg aagatatgat gcgttaatat ctagttattt
    44941 tgctggagaa gttggagata cgtatcctga catattaaat ttaactttcc aaaaagaaca
    45001 aactttaaga tatggagaaa atccacatca aaatggtttc ttatattcac agtcaaatgc
    45061 aaaaaatcca atcttaaatt atgagcaatt aggcggtaaa gaactttctt ttaacaactt
    45121 aaatgattta catggatgtt tagaagtaat gagagaattt aaagatagtg aagaagtagt
    45181 ttcagtagct ataaaacatg ctaattcatg tggggtaggt ttaggaaaag atgcttttga
    45241 agcatataca aaatgttatg aagcggataa ggtttcaata tttggaggaa tagtaggaat
    45301 aacttctact atagataaag ctacagcaga gaaattaaat gaaatattct tagaaatagt
    45361 agtagcatat gattttgaac cagaagcttt agagatactt aaacaaaaga aaaatctaag
    45421 aatattaaaa ttagctaaaa tagaaaatag tttacaacca tatgaaatga aatatttaga
    45481 tggaaaatta ttgatacaag atagaaataa tatattagca gaaaaaagtg aaaatgtaac
    45541 aaaggaaaaa ccaacagatg cacaacttaa ggacatggaa tttggtatga gagtagtaaa
    45601 aaatatgaaa tcaaatgcaa ttgcagtagt aaaaaatgga caaactctag ctttaggttg
    45661 tggacaaaca tcaagaattt gggcattaaa aaatgctctt gaaaataaca aagataaaga
    45721 ttttacagga gctgttttag cgtcagacgc atttttccca tttgatgatt gtgtaacatt
    45781 agctcatgaa tatggaatat cagcagtagt tcaaccaggt ggctctataa aagataaaga
    45841 ttcaatagaa gcttgtgaca agtatgatat ggttatggta tttacaggaa taagacactt
    45901 caaacactaa ggaggatatt atgaagatat tggttgtagg cggtggcgga agagagcatg
    45961 ctatatgctg gaaactaagc aaagaaaaaa atgtagaaaa aatttattgt gcaccaggta
    46021 atgcaggaat tgcaaacgta gcagaatgtg taaatatagg tgatactaat atagaagaac
    46081 ttttaaaatt tgccaaagaa aatgaaatag gtctgacaat agtaggacca gaagtaccac
    46141 tagttatggg aatagtagat gagtttgaaa aagaaggatt aagagtattt ggacctaata
    46201 aaaaatgtgc tcaacttgaa ggaagtaaag ctttttcaaa agaatttatg ataaaacata
    46261 acatacctac tgcaaaatat aaagaatata caaacttaga agaagctata tcagaaatag
    46321 atagttttgg atatccagta gtaataaaag cggacggatt agctgctgga aaaggtgttg
    46381 taatacctga aaatagagaa gatgctatag caactttaaa agaaatgatg tcagataaga
    46441 agtttggagc tgctggagat aaaatagtaa ttgaagagtt tttaaaagga atagaaactt
    46501 caattctagc atttgtagac aatgatacaa tagttcctat ggcaagtgca aaagaccata
    46561 aaaaagtaaa caactatgag caaggtccaa acactggggg aatgggaact ttttcaccta
    46621 gtgaaatata tacagaagaa ttagcaaata aagtaaaaga gacagtatta gaaaaaactt
    46681 tagaaggctt caaaaaagat ggacttaatt ttaaaggtat tttatttgtt ggtcttatga
    46741 taactgaaga tggagaaaaa gtacttgaat ataatgtaag atttggagac cctgagacac
    46801 aatctgtttt atttagatta gaaacagatt tacatgagat aatggaagct atactagata
    46861 ataagttaaa agatatagaa ataaactata gtgatgatga agctgtatgt gttatgctta
    46921 catcaggagg gtatccagac agttatgaaa aagggaaaat tataactggt cttgaaaact
    46981 tggatgatga tatagtagta ttccatagtg gcactaagat gtttgatggt aatttggtta
    47041 ccaatggagg aagagtaatt ggtataactg caaagtcaac tacagttaag gatgcagcag
    47101 aaaaagttta tgaaaacata aagaagataa actttgaagg aatgcactat agaacagaca
    47161 taggaagata atttttctaa aatggaggat aaggtatgtt gaatactgaa aataaagact
    47221 caatggttag aagagtattg gttgaaaaaa gagaaggttt tgaccttgag gctaaagctt
    47281 taaaaaaaga cttagtagaa agtttacaca tagataatat agaaaattta agaatattaa
    47341 atagatatga tgtagaagga atatcagaag aagtttatga aaatgcagca aagacaatat
    47401 tctctgaacc aaatttagat gtggtatatt atgaagaaat accaaaatta aatgatgaaa
    47461 gagtatttgc aatagaattt cttcctggtc aatacgacca aagaggtgat tgggcagctc
    47521 aatgtgtaca aattgtaaat caagggataa gacctgctat taatacagca aaagtttata
    47581 tattatcagg caaaataact gatgaagagt tttctaaaat aaaagattac tgtataaatc
    47641 cagtagatag tagagaagca tctttagaaa aaccagaaac gttaaaaatg gaaactgaaa
    47701 taccaacaac agttgaagta ttagatggat ttatagattt agatgaaaat ggattaagaa
    47761 catttgtaag tgaaaaagga ttagcaatga ctttaggaga cttacaacac gttcaaaaat
    47821 actttaaaga tacagaaaag agaaatccaa ctataacaga aataaaagta ttagatactt
    47881 attggtctga tcattgtaga catactactt ttatgactga aatagaaaat gtaaagatag
    47941 aagatggtaa gtttaatgat atagtaaaag aagcgtatca aatgtatctt aactcaagag
    48001 acaatgtata tgtgaacaga cataaagata tatgtttaat ggatatagcc actgttgcag
    48061 taaaagaatt aaagaaaaat gggaaattaa atgacctaga tgaaagtgaa gaaataaatg
    48121 catgtagtat aaacgtagat gttgaagttg atggtaagat ggaaaaatat ctagtaatgt
    48181 ttaaaaatga aactcacaac catccaactg aaatagaacc atttggtgga gcagctactt
    48241 gtttaggtgg agctataaga gacccattat caggaagaag ttatgtttat caagcaatgc
    48301 gtgttacagg aagtgctgac ccaagaacga ctttagaaga tactttacct ggaaaactta
    48361 tgcaaagaaa aataactaca gaagctgctc atggatatag ttcatatggt aaccaaatag
    48421 gtcttacaac tgggcaagtt gcagaagtat atgatgaaaa ctttgttgca aagagaatgg
    48481 aaataggtgc agttatagca gcagcaccaa aagagaatgt agtaagagaa agacctgaag
    48541 caggagatgt aatcgttctt cttggaggaa aaacaggaag agatggctgt ggaggagcaa
    48601 ctggttcatc taaagaacat agtgaagagt caatcttaac ttgtagtgca gaagttcaaa
    48661 aaggagatgc tcctaacgaa agaaaaatac aaagattctt tagaaataaa gaagttgctc
    48721 aaatgataaa aagatgtaat gattttggag caggtggagt ttgtgttgct ataggagaga
    48781 ttgctgatag cttagatata aacttagact tagttcctaa aaaatatgat ggacttgatg
    48841 gaactgagct tgcaatttca gagtcacaag agcgtatggc agtagccata aaaaaagaaa
    48901 ataaagataa atttatacaa ttagcagtag aagaaaactt agaagctaca catgtagcta
    48961 cagtaacaga tacaggatat ttaagaatgt tctggaatgg aaaagcaatt gtagatataa
    49021 atagagagtt tttagataca aacggagtaa aacaaactac tgatgttcat gttactaaag
    49081 tagatgaaga aaatacattc tttagctcta atgaaatagt aaaagatgtt aagtgtgcaa
    49141 gtatgaaaga caagtttaca aaagtactat ctgaccttaa tgtttgttct caaaaaggat
    49201 tagtagagat gtttgataat acaattggtg gtaatacagt acttatgcca tttggaggaa
    49261 agtatcaagc gactccaaca caaggtatgg ttgctaagat accagtactt ggaggagaaa
    49321 ctaatacttc tacaataatg acttatggat acaatccaaa ggtaggaaaa tggagtccat
    49381 tccatggtgc cttgtatgca gtagtagaat ctgtgtgtaa attggttgct attggaggaa
    49441 attatagtac aacaagactt acattccaag agtattttga aaaacttggt aacaatccag
    49501 aaaaatgggg taaaccattc tcagcacttt taggagcatt ttatgcacaa agtaaatttg
    49561 agatacctgc tataggtgga aaagacagta tgtctggtac atttaaagat attgaagttc
    49621 caccaacatt agtttcattt gctgttgaca cagtagatgc gaagaaagta gtatctccag
    49681 aatttaaaaa agcagactca aaagtagtaa tgttatgtgt aaacaaggca gaaaatgatg
    49741 ttgtagattt tgaggaatta aagagaaact tagataaagt aagagaactt atacatggaa
    49801 ataaagtttt atcaacatat gcattaggat ttgcaggtgt aggtgaagca ataagtaaaa
    49861 tggcttttgg taataaaata ggatttaagt ttagtgaaga ggctgaaaaa gcatttacag
    49921 atgataaatt atttgaggct agttatggaa atatagtact tgaattagca aatgatgatt
    49981 taagtatgtt agaaggatac aattatgttg tgcttggaag tacagttaaa gaagctagta
    50041 tatttatcaa aggtgaagaa cttgcattag atgaattata taaagcacat tgtagtactt
    50101 tagagcctat attcccaact aaaacagaag aagtaaaatc aaagatagaa actataagtt
    50161 atatatcaca aggagaagct aaaaaatcat cattaagtat agctactcca agagtattta
    50221 taccagcatt ccctggaaca aactgtgaat atgactctgc aagagcattt gaaagagcag
    50281 gagctaatgc aagtataaga gtatttaaga atttaactta taaagacata gaagattcta
    50341 tagatacaat agtaaacgaa ataaaatctt ctcaaataat aatgttacca ggtggattta
    50401 gtgctggtga tgagccagat ggttctggta aatttatagc tactgtattt agaaatccta
    50461 gagtgcaaga agctataaat gaatttttaa ctcaaaaaga tggactaatg ttaggtatct
    50521 gtaatggatt ccaagtatta attaaattag ggttagttcc atatggagaa ataagagttc
    50581 caagtgaaag tgctccaaca cttacttaca ataatattgg tcgccatcaa gctaagattg
    50641 ctagaactag aatttcatct aataaatctc cttggttagc tcaaactaat gttggagata
    50701 ttcataatat agcaatttct catggagaag gtaagtttgt tgccagtgaa gatgttatga
    50761 gagaattaat tgctaatgga caagtagcaa ctcaatatgt tgactttaat aatgaagcta
    50821 cttatgatat tgagtttaat ccaaatggtt cattctatgc tgttgaaggt ataactagtg
    50881 ctgatggtag agtgtttggt aaaatgggac attctgaaag aattggtgag gaagtatata
    50941 agaatattat aggtgaaaaa gaccaaaaga tatttgaatc tggagttaaa tattttagat
    51001 aaagctttga tgtttaattg atagctagaa tatataattt agatatttag atttaaagag
    51061 atgtaataat atgatgataa tcatttaata ttacatctct tttttattta tctaagaaat
    51121 aataagttca acctaagtta aaatacaagc tgtgttataa ttaattatta agtaaaattg
    51181 aatatttatt ggagggcaac ataattaatg aaaatattaa taacagggtc taatggtcaa
    51241 ttaggaaaag aattggttaa ccaattagaa gcaatcaatc aaagtataaa ccaaccaaaa
    51301 tatgttatat tagctacaac aagaagtgat ttggacatat ccaatcagac taatgtagat
    51361 aattttattt tgcataataa acctgatgta gttgtaaact gtgcagcata tacaaaggtt
    51421 gatgcatgtg aagataatat cgaaattgca tacaaaataa atgctttagg agtgagaaat
    51481 ctagcaatag catcagaaaa agttaatgct aagcttattc acatatcaac tgactatgta
    51541 ttcaatggtt tttctaaata tccatatagg gaagacaata aaactgaacc caattctgta
    51601 tatggaaaaa gtaaacttat gggagaaaaa tttgttgaac aattctcaca taagtacttt
    51661 atattgagaa cagcatggtt atatggtaat gggaataatt ttgtaaagac catgataaaa
    51721 ctttctttag aaaatacaga ggttaatgtg gttaatgacc agtttggaac tccaacaagt
    51781 acagtagact tagcaaaaat tataataaaa atcatggaaa cagaacatta tggagtttat
    51841 catgctacat gtgaaggtga gtgtagttgg tatgattttg ccaaaaagat atttaaacta
    51901 aaaaatatag atataaaagt aaatccaatt aagagtaacg aatttaaatg taaggctcca
    51961 agaccactat attctgtatt ggataatttt atgttgaagt taattggttt aaattctttt
    52021 agaaagtggg aagaatccat tgaagaatat ttagaaagat atgatataaa tgaaaagtaa
    52081 atgtattatt ttgagaaaag aaaataagat attataaaaa atataaatat ttcttttatt
    52141 tatccgataa tcataatatg acaaaaacaa atttaaggat ggaaaaagat gaaaggaatt
    52201 attttagcag gagggtctgg tacaagacta tatcctataa caaaatgtat atcaaaacaa
    52261 acacttccaa tatacgataa accaatgata tattacccta tgtcggttct tatgttggca
    52321 gggatacaag atatattaat aatatctaca ccaagagata taaaagcatt tgaagaatta
    52381 tttggagatg gaagttcact agggcttaac ataacatatg caattcagga gaaagcaaat
    52441 ggaattgcag aagcgtttat aataggagaa gaatttatag gaaatgacag agtgtctctt
    52501 gtattagggg ataatatatt ttatggatat ggatttagtg aaaggttgga gaatgcagtt
    52561 aaaagaaaag gagcaactat atttgggtat catgtaagta atccaaattc gtttggagtt
    52621 gtagaatttg ataaggattt taatgtattg tcaatagaag aaaaacctac agttcctaaa
    52681 tctaattatg ctataccagg attatatttt tatgataatg atgttgtaga gatagcaaag
    52741 ctagttgaac cgtcagatag aggtgaatta gaaataacct ctataaacag tgaatatcta
    52801 aaacgaggaa aactaaaagt ggaacttcta ggaagaggta tggcttggct tgatactggt
    52861 acacataaag gtctattgga tgcttctaat tatgttgaag tggttcaaac aagacaggga
    52921 ctgtatatag catgtttaga agagattgca tatacaaaag gatatataag tagagaacaa
    52981 ttaatgaaac tagccaagcc actgataaaa actgaatatg gtcaatatct attaaaattg
    53041 gctagtgaag atatgtaata tggtagataa aatttattat aaattttatt aagggagttt
    53101 attataatgg gaaaaatcaa tgttataaag actaaaatag aaggattata tatagtcgaa
    53161 ccaaatgtat tttatgatga aagaggatat tttatggaaa gctataataa aaaggatttt
    53221 atagagcagg gtcttgatat gtgctttatt caagataatg agtctagctc aagaaaaggc
    53281 gttttaagag gaatgcattt tcaggttaaa tatcctcaag gaaaattagt cagagttaca
    53341 gagggagaag ttttcgatgt tgcagttgat ttaaggaaag attcacaaac atttgggaaa
    53401 tgggaaggtg taatattgtc tgataagaat aaaaaacaat tttatattcc agaagggttt
    53461 gcacatggat ttttagtttt atcagaaaaa gcagtattta gttacaaatg tacaaattat
    53521 tattacccag aatttgagaa tggctttata tggaatgaca agcaaatatc tattgagtgg
    53581 cctttaaaag gaattgaaga aatattttta tcagaaaagg acaaaaaaca aaaaagtttt
    53641 aaagatattt gtacaagacg ttaataaaaa tttattagaa ttaacattta ggagaaaaaa
    53701 tatgaaaaaa atactgataa ctggaggagc aggatttatt gggagtaatt ttatacatta
    53761 tatgcttaac aagtatgtag attattttat tgttaaccta gacttgttga cttatgctgg
    53821 taatttagag acattaatag aaatacaaga caattccaat tataaatttg ttaaaggaga
    53881 tatttcaaat agggagcagg tgtataagct atttgaagaa gaaaggtttg atatagttgt
    53941 taactttgcc gctgaatctc atgtagatag gtcagttgag aatcctgatt tatttattaa
    54001 aacaaacatt ataggaacac aagtactttt agatgcatct ataaaatatg gagttaaaag
    54061 gtatcatcaa atatctacag acgaagtgta tggtgattta ccaattgata gaaaggattt
    54121 attctttaca gaacaatctt ctatcaatcc aagttctcca tattcagctt ctaaagcatc
    54181 agcagattta ttggtaagtt cttattatag aacatatgga ttgttaacaa ctatatctag
    54241 gtgttccaac aattatgggc catatcattt tcctgaaaaa ttgattcctc ttatgatttt
    54301 aaatgctttg gaaaacaaac aattgccagt atatgggaat ggggaaaatg taagagattg
    54361 gttacatgta tatgaccatt gtactgctat agacttaata atacataaag gaaatatagg
    54421 ggagatttac aatataggag gtcataatga aagaagtaat ctagaagtag taaaaatgat
    54481 attaaatctt ttaggtaaat ctgaagagtt aatatcctat gtaaatgata gacctggtca
    54541 tgatttaaga tatgctattg atgcaactaa aatagagaat gagttaggtt ggaaggcaaa
    54601 atatgacttt gatttgggta taaaagaaac tgttaagtgg tatatagaaa atgaatcttg
    54661 gtggaaagct gttttatcag tataacttta aaatttagaa aggggcgttt tatattgaat
    54721 gagataagtt cactaattaa tatattagca ttgactcaat tatctggtag taatactaca
    54781 aatcaatgta attgtacata taataattca tctggatttg atatgattat gatgaccttg
    54841 ttaaaagcat tatcacaaaa taatcaacat acttctaata gctacaattt attgtctaat
    54901 tctgagaatt tatttaatga acttgataat gtagtaaata ataccactag tagatttata
    54961 gatgttgata caaaagataa aaatgtaaag ttgagaattg aaaatgctgt agatcaagca
    55021 tcaaaaaaat ataacgtaga ttcaaatctt ataaaagcaa taattaaagt tgaatcagat
    55081 tttaatccaa ataccgtttc ttctgctggt gctaagggtc ttatgcaact tatgccagaa
    55141 aactgcagag acttaggagt tacagaccct tttaatatag aacagaatat agatgctgga
    55201 actagacata ttaaggaata cattgatatg tttggaggga gcatagaaat gggattgatg
    55261 gcatataatg gtggtcctgg aagaatgaaa agtagaggag tagaatcaat ctctgacctg
    55321 tataaaatgc caaaagaaac acaaaattat attcctaagg ttatgaaata ttatagaggg
    55381 taggctttat tatgggaata aatatagata agctaaacat aagtccaagt ataaatatgg
    55441 aggttaaaaa actaaaagag agtaataaat tttctgacaa attaaactct ttaaaacaat
    55501 cttcttcatt ggaagatata aaacgaaatt tggaaagtgt aaaaaaggca ggagaaaggc
    55561 ttgtacttac tcaaaactat ggcgatatta gtatatataa aaatgcagta aaagaatacc
    55621 taaaatctgt tgtagataat atgtattcac ttgataaaaa tagtagcttt tgggagcatc
    55681 agtattataa gaatgtaaag attgttgata gtaaacttga ggatatgact agtaagttaa
    55741 ttagtgaaga aaaagaaaac atagatattg tttctactgt tgacatgata caaggcttat
    55801 tgatagatat gtatagataa ggttatacaa ggagaaaaat tttatgaata gcaaaaaaga
    55861 ggatatatat gaattgaatt ttgggcaatt aatagaagaa aaatctggtg ttatagaaga
    55921 aaatcaaaat gtttttaatg caaaagtaaa tgtagctgtt tctataggaa atacaacaga
    55981 aacaataaaa aatatattag atttaaaaga aggctctata ataaaattaa gtaagaatgt
    56041 ggatgaaaaa ttagatatat atgcaaacga tagattgttt gcttatggag aaagcattat
    56101 tacaaatgag aggttatctg taagattatc taaaatagaa gatccagatg taaattagca
    56161 ttttaaatag tatcccttta ggctattctg tatgagttta gctaagggga tatttttata
    56221 aaaaatttaa aatatgtgtg aattatataa atatttttat tttatgagcg ataactaaat
    56281 tataagtatg taattttgga ggtgaaacta tggatattaa aaatgtaagt tcaaacattg
    56341 tagtgaataa ttatttaaag aatacatctg gtataaaaaa agtggaagag gttaaaaaaa
    56401 ttaataaaac agacaagata gagttatcta aatttgcaaa ggaaatggca agtgtgtcaa
    56461 atatgagtga tgagaatatt agaaataaaa aagtcgatga aataaaaaat gcattagaaa
    56521 atggaactta caaaataaaa ccaaaagaaa ttgcgaaaaa aatgatagag gatatgcgag
    56581 gataaagtca tgattacaga cttaaaagtt ataatatatg aagaaaaaaa tataattagt
    56641 aagatgatgg aattattaaa agaacaattt gattatatag ttgaaaaaga cttagaaaat
    56701 ttaaatatgt taaatcctaa actagaagat attagcaggg agcttgcatc catagaaata
    56761 aagagaagac aactttttgg tgatgatatt tcaatgagtg aagttgttga aaatagtaat
    56821 gatggatact taaaagaaat atatacagac ttgaaacaca ttcttgcttt agctaaaaat
    56881 caacaagaat caaatgattc tctaataaag aaagaactta tttttacgaa aaaaatgatt
    56941 aatttcataa aaccagctga taagaaaact acaacttata attcttatgg aaatattaga
    57001 aaataaatat taggaggaga aatatggcag gattattttc cattttaaat acagctaatt
    57061 caggaatgaa tgcgcaccaa aaagcaatac agacaatttc tcataatata agtaatctag
    57121 atacagacgg ttattctagg caaaggaccg agtttgccac aaatagtcca atgtatatgc
    57181 ctagtttgag taattcaatt gcaagaggac aattagggac tggagtacat gtaacggatg
    57241 taacaagagc tagaaatagt ttttatgatt accaatttag ggcagaagct cataagtatg
    57301 gtaagacagt ttcaaaatat gattattaca atactataga aactatacta aatgaaccat
    57361 cagactatgg aatatctgca ggtatagatg atttttttaa aggatgggag tcattatcaa
    57421 aggatataaa tagtgacagt aaaaaaagtc tagtggtaga aaacgcatct aatttagcaa
    57481 ctttaataag tgaaagttat aagaagcttg ataagttaaa agaagatata gattctaata
    57541 tagacactga gataaaacaa ataaatgaca tgttaaaaag tcttgaagat ttaaataaat
    57601 ctattgatat tatatctggt tctggctcta caccaaatga tttacttgat gaaagagata
    57661 gaattttaga taacttgagt tttaaactag actttgaaaa tagtgatgtt aaaaatatgc
    57721 ttgcagatgg taaattagaa cttaatgaat taaaaaatcc agatggaact tggaaaacag
    57781 gtatatcagg gaccttacaa ggcttgtttg aaatgcatgg taagattgat acatataaaa
    57841 gcgatttaaa agatgtatct gatggattag ctaaacagat aaatgatgtt tataatacgt
    57901 ctgcaggaat aacagtaaca gattttttta taacttcaaa tgtagatggt gaagatatta
    57961 taaagataaa tccagctata aagagtaacc caaatgaatt aaagcttact gctgatgaag
    58021 cttcaaaaat tgctaagtta aaggatgaaa aaatagatat tggggtggct ggtggaaaag
    58081 taagtacaat aagtgaccac tataaagcct ttgcagaatc aatcggttta gattctcaaa
    58141 aagtaaatca agatgaagca aatcaacgta aaattataaa taatattgat aactcaagaa
    58201 tgagtgtttc aggtgtatct ttggatgaag aaatgacaga gcttataaaa atacaacgtt
    58261 catatcaagc tagtgcaaaa gttatgtcaa cagctgtgca actactggat gttgtaataa
    58321 atggaataat ttaatagaag ggggaattta taatgagagt cagtacaggt atgatgtcta
    58381 gcagctatct aaactcacta caagataatc tacaaagatt ggataaggtt aatagacaag
    58441 ttaatacaac aaaagaaata aacaagctat cagataatcc atataaagca ataaagatat
    58501 taaactcaaa aagtgaaata aagactatgg agacttatgt tgagaattgt aaagatacag
    58561 ggaattggtt agaaactact gatactgcat tagatcagct tggaaaatta ttatcagaca
    58621 taaagaaaac tttggtggca agtggtgatg gtgcatactc agatgatgaa ttaaagactc
    58681 ttagtaatga aactaatgaa aaaatgaaag aaattgcaaa tgctttaaat gcaacacatg
    58741 aagggaagta catattttca ggttcaaata cgggggtacc acctgttgaa tgtatagata
    58801 atgctgatgg ttcagtgagt ttaaagttta attctagtct aaatcttaat aaattaaatg
    58861 actctttgag tatggatata gctcaaggaa taagtgtaga ttataacgtt aaattgagta
    58921 gccttggatt tgacccaaca aaaactgacc catttgaaga gttaaataac atatcaaaaa
    58981 aattagcaaa tccagatgct gatgctataa aagagcttac aacaacttgt ttgggcgata
    59041 tggaacaact aatagaaaat acagtaaatg ttaggtctat atatgggaca aaagcaaata
    59101 cagtagaggc tatgaaggaa aaaaacgatg atagtttgat acagttaaag gatattttgt
    59161 cacaaaatga agaaatagat tatggtgaaa aacttgttca attaaaggca gcagagttaa
    59221 cttatcaagc ttcactacaa acaggaggaa agttatttaa tgtatctata ttagattaca
    59281 tataataaaa taacgcagat atgatgaagg ttacattaaa aaaaggtata ttaggttttg
    59341 aaaatttaaa agaatatgag cttttagata tagaagataa tgattattta aaagaattta
    59401 attctactga agaagaaggt ataggatttg ttgttgtatc tccatttgag attatcaatg
    59461 aatatgaaat agttttaaat caggaaacaa tagaaaaact agaagtgaaa tctccaaagg
    59521 atgttgtatt atttaatata attactcttg gtcagacatt tgaagaatca actgtgaaca
    59581 tgaaagctcc tatagtgata aatataaaaa ctaattttgg aatgcaaata attttacagg
    59641 atgataaata ttcaataagg catccattat tgagaggtga tagtggatgc tagtaatttc
    59701 aagaaaaaaa gatgaagcag tacttatagg agaaagcata gaagtaaaaa ttgtaggggt
    59761 agatggaaac aatgtgaaac tagctatatc ggcgcctaac aatataagta tattaagaaa
    59821 agaaatatac gaaaaagtaa agagtgagaa tataaaagct acaaataaaa atataaaaat
    59881 tttaaagtca ttaaaataat aagcttggag gaagtaatat atgtatggag aaaatcctta
    59941 taattcttat aaacaaaatg ctgtttttat ggcatcaaag gaacaattgt tacttatgct
    60001 tgttgatgga gcagtaaaat ataccaaaat agccagagca gctatcttag ataaaaatac
    60061 acagaaagcg catagagaac ttgtaagagt tcaggatata tttacagaac taatggttac
    60121 attagaccaa aatgcaggac aatgggcaaa ggatatgtac aaagtttatg attttgtaag
    60181 atatgaactt tcaagagcca atattagaaa agacatccag gtaatagata atgtgttacc
    60241 tgtaatagaa caaattaaag atacatggca tgaagctgat aaaaaaagta aagaagaaag
    60301 aagtaggtac aaataatgga attaaattta gctgaattag ataagttatc aaaagaggaa
    60361 ttactattga tgcttgtaga tggcacagta aaatatacca atatatccaa agaagctctt
    60421 ttaaataacg actatttgaa agcacataat gaacttgtaa gagttcaaaa tatatttaca
    60481 gaactaatga ctacattaga ccaaaatgca ggacaatggg caaaggatat gtataaagtt
    60541 tatgaattta taaaatctga attagcaata gctgatgaaa ataaagatat taaaataatt
    60601 gatgatatat tgccaatagt aaaacaaatt agagatacat ggcatgaagt ttacaatcaa
    60661 ctaaaaatat aattagatgg agggataaag gtatgtcaag tataagtcct ataagagtta
    60721 caggtctttc aggaaatttt gatatggaag gcataatcga agctagtatg attagagaca
    60781 aggaaaaagt tgataaagca aaacaagaac aacaaatcgt taaatggaag caagaaatat
    60841 atagaaatgt tatacaagaa tcaaaagatc tttatgataa atatctaagc ataaattctc
    60901 ctaatagtat agtaagtgaa aaagcatact cttctacaag aataaccagt tctgatgaaa
    60961 gtattatagt agcaaaaggt tcagctggtg cagaaaaaat aaattatcaa tttgcagttt
    61021 ctcaaatggc tgaaccagca aaatttacta ttaaattaaa ttcaagtgaa cctattgttc
    61081 gacagttccc tccaaatgcc agtggagcta gttctttaac tataggagat gtaaatatac
    61141 caatatctga acaagatact acaagtacta ttgtaagtaa gataaactcc ctttgcgcag
    61201 ataatgatat aaaggcttct tatagtgaga tgacaggtga attgattatt tcaagaaaac
    61261 agactggttc gtcatcagac attaatttaa gagtaattgg aaatgacaat ttagctcagc
    61321 aaattgctaa tgataatggt atcacattta taaatgatgc tggtggaaac aaatttgcaa
    61381 atgtatatgg aaagaatcta gaagctgatg taactgatga acatggaaga gtaactcata
    61441 taagtaaaga acaaaattca tttaatatag ataatattga ctataatgta aattcaaaag
    61501 gaactgcaaa gttgacttct gtaactgata ctgaagaagc tgttaaaaat atgcaagcat
    61561 ttgtggatga ttataataaa ctgatggaca aggtctatgg tttagttact actaaaaaat
    61621 caaaagatta tccacctctt acagatgccc aaaaagaaga tatgacaact gaagaaatag
    61681 aaaaatggga aaagaaagct aaagaaggta tacttagaaa tgatgatgag ttaagagctt
    61741 ttgttgaaga tattcagtct gcattttttg gagatggaaa aaatattatt gcattaagaa
    61801 aactaggtat caatgaaagc gaaaattaca ataaaaaagg tcaaatatca tttaatgcag
    61861 atactttttc aaaggctctt atagatgata gtgataaggt atacaaaaca ctagcaggtt
    61921 attcttcgaa ttatgatgat aagggaatgt ttgaaaagct aaaagatatt gtatatgaat
    61981 attctggaag ttcaacttct aaacttccta aaaaagcagg tatagaaaaa actgcttctg
    62041 ctagtgaaaa tgtatattca aaacaaattg cagagcaaga aagaaatata agcaggttag
    62101 ttgaaaaaat gaatgataaa gagaaaagac tttatgctaa atattcagcc ttagaatctt
    62161 tgttgaatca gtattcttcc caaatgaatt atttctcaca agcacagggt aattaattat
    62221 ggataaatta aaagaaaaat taaatttata taaagatata tctttacaaa ttataaattt
    62281 gattgaaaag gaagaatata taaatataag tagtaagtta ggtgaaagac aagagattat
    62341 aaatagtgta agtgaaattg atagaaatga ttttatacag ctttataata gaatggaatt
    62401 aattgaaatt gatagtagga taagagatat tttacaagga caattattag aagtaaaaaa
    62461 agaattacat gagtataagc ttactaaaca agtgaacaca atgtattata acttaaatag
    62521 agaaaaagta aatattttta ataaaaaagt ataaagttat gtaccatctt gtccgattat
    62581 ataaatgaag aattaataaa aaagattaaa agtagaaatg acaaggatgt caactatact
    62641 aaggagggta aaataatgag agttaataca aatgtaagtg ctttggtagc aaataaccaa
    62701 atgggaagaa acgtaaatgc acaaagtaag tctatggaga agctatcttc tggtgttaga
    62761 attaagagag ctgctgacga tgctgctggg cttgctatat ctgagaaaat gagagctcaa
    62821 ataaaaggtt tagaccaagc aggaagaaac gttcaagatg gtatatctgt tgtacaaaca
    62881 gcagaaggtg cattagaaga aactggtaac atactacaaa gaatgagaac tttatcatta
    62941 caatcttcaa atgaaactaa tactgctgaa gaaagacaaa aggtagctga tgagttatta
    63001 caattaaaag atgaagttga aagaatatca agctcaattg agtttaatgg taagaaatta
    63061 cttgatggaa gttctacaga aataagatta caagttggag caaactttgg aacaaatgtt
    63121 gcaggaacaa ctaacaacaa caatgaaata aaagttgctc tagtaaatac ttcaagtata
    63181 atgagtaaag caggtataac aagttctaca atagcaagct tgaatgtaga tggagcttct
    63241 ggaacagatg cagctaaaca aatggtgtct agcttagata tggctcttaa agaattaaat
    63301 acatcaagag caaaattagg ggcacaacaa aatagactag aatcaactca aaacaactta
    63361 aataatacta tagaaaatgt tacagcagct gaatcaagaa taagagatac agatgttgct
    63421 tcagaaatgg ttaacttatc taaaatgaat atattagttc aagcatcaca gtcaatgctt
    63481 gctcaagcta atcaacaacc acaaggagtt ttacaattat taggataaaa taattttgta
    63541 tattggatat agaagaaagg gtaaggcttt gctttactcc tttctttttt tacaaatata
    63601 cttttgaaag gaaaatttat atgttactta gtatagttat gattgttaaa aatgaagaaa
    63661 aaatacttga aaaaacttta aaatcattaa ccacattaag aaattctata gaaagtgaac
    63721 ttataatagt cgatacaggt tctacagatg atactataaa tatatctagg aaatacacag
    63781 aaaatgtgta ctttcataat tggaataatg atttttctag tatgagaaat atatcaatat
    63841 cttatgccaa gggcgaatgg ttacttatat tagatgcaga tgaaatatta attgattctt
    63901 caactattgt aaaatttttc aaggacggtc ttgataaaaa atttaattct gcttcaatac
    63961 aattaaaaaa tctttactca tacgataaaa aattatatgg atattgttcg gtgcttagac
    64021 tttttaaaaa cgttgatttt agataccatg gtaaagtaca tgaacaacca atatacaaaa
    64081 atcctatatt taataatgtt gctgattttg aacattatgg atatttgttt gaagatgaag
    64141 aaataagatt aaataaggtg aaaagaaatg aaaaactatt atttcaagag ttaaaagaga
    64201 atgataattc tccatataca aactatcaat tggggaaaaa ttttattata ttaggaaaat
    64261 atcaggaggc tttatactat cttgagaaat cttatgaatt atattctaaa ctagaatcgg
    64321 cacctggtta cttgataaca agccttgtaa aaacatattt atatttagga aaacataaga
    64381 agtgtgaaaa attgtgctta aagtatatta agaaagacat gaataatatt gatatatatt
    64441 attatattgc acaagcacaa gtagatttag gaaagtatga aaatagtata gattcgtata
    64501 agagatatat ttacttgtta gataattatg aaataagtac acaagcaaat agtttatttt
    64561 cagacactga tactgtaggg cttagagatg aggctattat tacactgata aagatttatt
    64621 ataagcttga aaaatatgag tttgtaattt cagagtacaa taacattgaa gatgtggaaa
    64681 agaaaaagaa tgtgtacttt agcttattta tgtccctata taaattgaat agatttgaag
    64741 atataaaaaa ttattataaa gaagtttcaa attctaaaat tgaaaaaaat agtttttata
    64801 gaaatataga agaagttata aataatatta aagaggatga aaaagagtat gtatataaaa
    64861 tcctttgtga cattgagggt aattatggca ttttaaatca aataaggaca aataaatgtg
    64921 tatctataga taaatgtaaa gaaatactca atgaagaaaa ggaaataatt tatgcatata
    64981 ttataaaaat agcttttgaa gagaagattg atttactaga tattttttat gaaatggaat
    65041 atgtatggat agagaaatat ctaaaatatc ttttagcatt agaaagaagt tttaatttag
    65101 tactatataa gtacataatt agtcgtccaa atacatcaga tatggaaaag ataagagtat
    65161 ataaagctat atctaaagta gttttagaaa gtataagctt aagtgatgaa aaatataagg
    65221 agatttttta tttttatata atgtattctt ataagtatat aagatacata tatagcaatt
    65281 taagtgattt tgaattaaaa aaatttgttt gcaatgattt agataagttc actatagaat
    65341 ttaagcatct acttgacatt aaaaatagag taaataatgc taatgaaaaa ttagagtata
    65401 tacatagtat gaggaaatta ctaaatgagt atccttttta taataaaata ataaaaatac
    65461 ttatatgtga attagaagaa aatataaaag aaagtgaaga atttaaggat ttaaaagata
    65521 gttttattat tagtatagaa aatatgattg aaactggcaa aataaatgat gcgaaattat
    65581 tggtagatga ctattcaaaa acatttgtgg atgatataaa gattttaaat ataaagggaa
    65641 ttttatacat gcttgaaaat aagcttgata aagctgattt tatgttaaaa aaggcattat
    65701 cattagatgt agaaaatgaa gatactatat ataatataga atacttaaaa agcttaagat
    65761 aagtcaaaaa taggagaatt gaagaatgaa tataccaata gtggttaatg aaaaatctaa
    65821 agatataata aaagattggc aatatacgtg tacaaacgaa gatataaaat ttacaagcat
    65881 aataatattg acatataatc aaatagaata tactaaatta tgtattgaaa gtattaggaa
    65941 atttacccca aagaataaat atgaaataat aataattgac aataactctt ctgatggaac
    66001 agttgagtgg ttaaagagac aatctgatat aaaatctgtg tataataaca aaaacttagg
    66061 atttccaaaa ggatgcaatc aaggtattga attagctact ggtgaaaaca tattgttgtt
    66121 aaataatgat gtaatagtta ctccaaattg gctctataat ttgaataaag ctttatggtc
    66181 tcaagataat ataggtgctg taggacctat tacaaatgca tgttcatatt atcagcaaat
    66241 tgatgttgat tataagtcaa ttgaggacat gtttatattt gcacacaaaa taaataaatc
    66301 tagtattaac ctatggaaat atagattaaa gttagttgga ttttgcatgt taataaaaaa
    66361 aactgttctg gataatgtag gggttttaga tgaattattc acacctggaa attttgaaga
    66421 tgatgattta tcttttagga tgatagagtc aggatataag ttattattat gccaggatac
    66481 ttttatacac cattttggaa gtgtgtcttt taaagaaaat cgtaataaat atacggatat
    66541 aatgtatatt aatagaagaa aatttgaaac taagtgggga tttaatccag aatatagtgg
    66601 aatgataaga acagatttga tttctaaaat agatgatagt ttggaggcaa atatcaatgt
    66661 tttagaaata ggctgtggta taggggctac tcttttagaa ataaaaaata tatataaaaa
    66721 tgcatcaata tatggaatag aaattagtga gtcagcaggt aaacttgcaa agtatagtgc
    66781 agatgtactt atagcagata tagaaaaagt aaaattggat tataaaaaag atttttttga
    66841 ttatataata ttgggagata tacttgaaca tttgattgat ccatggaaga tagtcaatga
    66901 attgaaacaa tatctaaaaa aggatggtta tctggtatct agtataccaa atattatgca
    66961 tgtttctgtt ttaagaaatc ttgtgttagg taattttaca tatgaagatt caggaatttt
    67021 ggacaagact cacttaaggt tttttacatt aaatgagata acaaaaatgt ttaatgatag
    67081 taattacata ataaatagta ttacagctac tagtatgcca ctttcggaaa ttgataatag
    67141 cttcattgat acaatatgta aggaaagctg taaagaaatg agacaacagt acgaatctta
    67201 tcaatatata gtaaaagcct ctaaaatcct agatactaaa agatattcta gtattagtat
    67261 ggttaattta aaatacgctt taatgagaat tgataatgaa ttagatgtag atagtaattt
    67321 aagttatata tttgataatt ataatataac tgaaccatgt tttgttgatg atattgaata
    67381 tctaattgat acgtttgtga taaataaagc aactctatta aatagattag gagttgaggc
    67441 atttaacaga ggtctaggag attttagtat aaacatgttt atgacagtat tagagatgga
    67501 tagagatgat attgactcaa tatataatat aacaagtgta ttatgtgaat tagaagaatt
    67561 tgatactgct tataatttaa ttaaaaatag tagcgaaaaa gtacagagtg aaagtgatat
    67621 acaagagata ctttgtttta ttgaggggaa gaaatatgaa taatgataag atatgtttta
    67681 taacctgtgt aaatgatgaa aggctttatg aagaatgtct tgtatatata aatagcctag
    67741 acattcctaa aaactttagt atagaaacag tagctttaag aggagccgat tctattgcct
    67801 ctgcttataa taaagctatg agagaaacag attctaagta taaggtatac ttacatcaag
    67861 atacttttat aattaataaa aatttcatac atgatatttt agagatattt aaaaaaaata
    67921 cagatgtcgg aatgattggt gtagctggag taaaagatat gcctgtgaat ggaatttggt
    67981 gggattctga taaaaaagca gggaaagtat atgatagtca tacaggtaaa atggatattt
    68041 atgaatttag taactttgaa gaatgtttta atgaagttat ggctatagat ggattaatta
    68101 tgattactca atatgatgta ttttggagag aggataagtt tgatgggtgg catttttatg
    68161 atttgtcaca gagtatggag tttagacaaa ataaatacaa agttattgta ccaaaacaaa
    68221 ataagccttg gtgtatgcat gattctggag tagtaaatat aaataatgga tatgatgaat
    68281 ataggataaa atttgtaaaa gagtacataa atcttgattt atatagagaa aatttttatg
    68341 aatttgataa gaagaaagca agtaccatac ttaagagtaa taagcatgta atggattgta
    68401 tgaaagagga gcttacagaa caattaagat taaagaatta caaggatgtt ttaggtattg
    68461 tttctaaaat tgctcatttt tctgttttta atcatactgg tttgtattct tgtgaagaat
    68521 gtgagagagc attgctagaa tgtgcaaata atttaccaga aatagaaaat acgaaattat
    68581 ttacaaaaaa agatttaaaa agaagaaaag tattacatgt tttaagtgaa ggatattcaa
    68641 caggaggtca tacaagacta gttaaaaatt ggattgaaat tgacaaagac tctgttcatt
    68701 cagttgtaac cacatggcaa tcagatacac tgccagactg gttattaaaa gcaatagatg
    68761 atagtggtgg cgaagttata tctttggatt taatttcaga tgattgttta aaaagagcta
    68821 tggctttgag aaaaatagct tatgactggg ctgatatagt tattttatat gttcatatgt
    68881 gggatacaat acctgttgtt gcttttggag ttgatggaaa aatacctatt ttacatgtta
    68941 atcactatga cagtactttt tggttaggga caagtattgc agatattgtt attgatttta
    69001 gcgaagctag tcaattaatt acattagata aaagaggcat agataaatct gaaatattac
    69061 caatgccatt aaaagaaaaa gaagtatttt caaaatctga agttagaaaa cgatataatt
    69121 tggaggatga tgtgacaata atattgacta ttgctagtga aagaaaatac aatagtgtaa
    69181 atgatattaa ttactttaaa attgctaaaa cattgattga aaatacagat aatacaatta
    69241 ttattgttgt aggagttgat acagagaatc tttattggaa aactttaagt aacgttacag
    69301 ataatagagt tatatgtttt ggaacaacag caaatataga cgatttttac aagatttcgg
    69361 atatatatat ggagtctttc atggtaggaa gtcatacttc aaaactagat gcaattttat
    69421 atgatttaat tcctgttaag tttaaaaatg aagtttcacc aatttttaca aatatgtgga
    69481 attttataga taagtttgat tataagaata taaaagaggt tatagatatg ataaaaaggt
    69541 acaatactag tgaatttgac agggatagga taaaagaaaa acaatcagaa ataaaacatt
    69601 ttgttataga taaacactgt attgaaataa aaaactatat agacaaaata tataatgaag
    69661 ctaatcatca taaagttaag tatgatttat ataaaaatga tgaaatcgag gactatcagc
    69721 tttttgtagc attatatggc tatatggtaa aaaataaaaa catgtcatag gtggtaaaat
    69781 gaacaatatt catatcaata aatttgaaaa aagctgtgaa aaaaactggg attattttgt
    69841 agaaaataaa tctataaatg gtacatttct gcaaactaga aatttcctta attatcatga
    69901 ggagggaaaa ttcactgacc actcattaat aatatgtaaa ggtgaagaaa tactagcagt
    69961 cgtacctgca tgtgaaactt atgaagatgg tgaaagaata tttttttctc atttagggag
    70021 tacttttggt ggtattataa taagaagtgg ttttaatgat attaggcatg taaatgccat
    70081 tacaaataag ttagaaatat atttacggga acaaaatttc gataaagtat atttaaaaaa
    70141 tacatcaaga atattttgta aagaggatac ttcattacta gaatattttt tatttaagaa
    70201 taattacatg ttttatgatg aattaagtat gtttttagaa ttaagtaagt ataaagaaga
    70261 tatattagcc aattttaaat acagtaaaag aagagatttt aaatattctt tgaagaataa
    70321 tcttaccttt aaaagactgt atagtgatga agatatagtt tgttttttta atttactttc
    70381 taattgttta gatagtaaag gagctaaagt aatacattca gtagaagaac ttttggagtt
    70441 taaaaataat agattaaaag atattgtaga attttatgca gtatatattg atgacattat
    70501 gatttgtggg agcatggtat ttaactttca agaaagagtt tatcatactc aatatctagc
    70561 atcaaattcg acatataata aatattatcc aatgatattt ttatactata atctaataaa
    70621 agatgcttta gagagaaatt ttaagtatct ttcttttgga attagcactc taaatagagg
    70681 caaatactta gacgagggtt tagctacatt taaagaaggt tttggttcaa gtgcaatttg
    70741 taacagaaca tactataaaa atataaataa gtgagaatca tgttttatag agtttttaga
    70801 gtatagtaaa tatctagtac tctaatatta cataaaaata attagtttat aaagaaggtt
    70861 tgtatatgaa aagattaatg attttaggct caattaagta ttttgagaat attgttatat
    70921 cagctaaaaa agagggaata tatacaattg tttgtgataa tagaattgat actcctgcga
    70981 aaaagatttg tgatgaagca atagatgttg atgtatttga ttttgataaa ataaaaagta
    71041 tagctataga taaaaagata gatggaattt taactggatt tacagattct ttaatgaaac
    71101 catatgttta tattgcaaat gaactaaatt taccatgtgt gatttcttgc aatcaacttg
    71161 aatctgtaac taacaaggct attatgaaaa aatattttaa aaataatgca atacctacaa
    71221 ctgattattg tattattgaa agtctaaaag atttagaaaa aatacaaaga ttaaattttc
    71281 cacttgtaat aaaacctgtt gatggttatg gttcaagagg tgtatatttt gtatcaaata
    71341 tggaagaatt aatagaaaaa tttgaatatt ctaaggaagc ctcacaagat ggacaagtaa
    71401 taattgagga attttatgaa agtgaggaaa tacaagggct agcttgggtt cataatggag
    71461 agtcacatgt attttatatt ggagatagag agcttgtaaa catacataca ggaagagctg
    71521 gaaaaccaga tagattactt tatccatcaa agtattgttt tcaatatgag gaggaaataa
    71581 aatctatata tcaaaatata acacaggctt ttgatataaa aaatggacct ctttatgtac
    71641 aaatgttagt gggagcatat ggaataaagg tatctgaagt aatgccaaga ttacctggag
    71701 gttgtgacta tatggctatt tctcaaataa cagatttaga cataggaagt ttatttgcaa
    71761 actttagtgt gaataatgaa gtaaattttg atgaaataaa gaaatataat atgcatctat
    71821 caaaatgtgt atatgcatta ccaatataca taagacctgg gacaataaaa aagataaata
    71881 atatagataa aatagaaaac ttagattatg tcactcaatt tctattacta gtaaaagaag
    71941 gagatacaat agaattatat gaagatgaga gacaggattg tggaagagtt tatggaatag
    72001 caaataatat atttgatgca aatataaaaa agaaatgtat tcatgaaatg atagaaatac
    72061 ttgatgaaaa taatgaaaat atgatagaaa atttttaaat aagggagtat gatagatatg
    72121 aagttaataa ctcatgaaca aattatgtca ttaaacattt ctcagaaaca aggatatgag
    72181 tggataaaag aatccttctt aacaaaaaaa gattgtcaat taccaccaaa aataagcatg
    72241 gtagaagaag gacatgtatt ttacaatgta atgccatccc taaatcataa tcatatgatt
    72301 ggtggaataa aaatggttac aagattgcca gggagaaatc caagtttaaa ctcagagata
    72361 tttctatata atatggaaga tgctaaatta aaggctattt tggatggtaa ttatattaca
    72421 gcttttagga ctgctgctgt tgctgccttg gctatcgata catttgctaa aaaagatttt
    72481 aatactattg ctattatggg tttaggtgtc actgcttctg ctataatgaa tatgctttca
    72541 tatactctta aagataaaaa tataaatata aagttactta aatataaaga ccaagcagag
    72601 tcgtttgtaa aaaagtatga aaaaaatgaa caatttagtt ttgaaatatg tgatacacat
    72661 gaagaactta ttgtagattc agatgtagtt atttctactg tgacatatac agatgaatat
    72721 ttatcagaat ttaaatggtt taaaaaaggt gctttattat tacctgtaca tgttatggga
    72781 tttggaaatg ttgattatct atttgataaa gtatatttag atgattataa tcatttgaaa
    72841 catctagaaa atatagatag atataaatat tcttgtgaat tttatgatgt tttaagtaaa
    72901 caagctaaag gaagagaaaa tgatgatgag agaataatat cttacaatat aggtttgtca
    72961 atacatgata tattatttgc aaataaaatt tacgaattgt gtgaaacact aagctgtgaa
    73021 gaaatagaat taaaagaacc aaaagaaaaa tattggatat agtttatttc attcatattt
    73081 acaatagttt attgtaaata tgaatatgaa gtaatatatt gttagaaaat tagcatgaat
    73141 aggatagata aatttatgga taaatataat ttaattaggt tcgtatctat tggaaacgaa
    73201 tatataggaa atttagttgc attagaatca aataaagtaa taccttttga tataaagaga
    73261 gtttattaca tatatgatgt accaaacaat gtaaagagag gatttcatgc acacaaaaac
    73321 ttggaacaag tactagtttg cctaaatgga agtgtgaaga taaaatgtta tgatggtgta
    73381 aaagagacta tatttaattt acataaaaat gatgttggat tatatatagg aacgggagtg
    73441 tggcatgaga tgtttgattt tgatgaaaaa actgttttaa tttctatagc atctgaacat
    73501 tataatgaag aagattatat tagagactat aaagaatttt taaagtattt aaataatatg
    73561 tagttattat acaattagtg atgtattttc ttaattaaat aaatttaaga tagccacata
    73621 gagaatagat agattaggat gtgaatttat tgttggttaa atttaataat ttattaaaac
    73681 agttccaaac tcataaagaa gaatatgaac agaagattaa ggatgtaatg gaaagtggat
    73741 attatatcct tggaaatgaa gtaaagcatt ttgaagaaga atttgctaac tatgtaggta
    73801 gcaaatattg tgttggttta gccagtggtt tagatgcact gataattgct tttagagcat
    73861 taggaataag caaaggtgat gaagtaatcg tgcaatcaaa tacatatatt gctagtgtta
    73921 tgggaatcag tataaatgga gcaacaccag tatttgtaga accaaatgaa tattataata
    73981 tagattcatc taagatagaa gaaaagataa atagcaaaac aaaagctata ttagtagtgc
    74041 atttatatgg tcaagcaagt aatatgaaag atatacaaga attatgtgat aagtataact
    74101 tgtatttaat tgaagattgt gctcaatctc atggagctaa atatgatgga aaaatgacag
    74161 gaacatttgg tgatataggt tgttttagtt tttatccaag taaaaatttg ggtgcatttg
    74221 gagatgcagg agctatagta actagtaatg aggaaatagc tgataaagtg aaaattctta
    74281 gaaactatgg ctcagaaaag cgatattata ataaatttgt cggatataat tcaagattgg
    74341 acgaaattca ggcaggttta ttaagagtaa aacttaaata tctaaatgaa attgaaattg
    74401 aaaaatcaaa aatcgtagat agatatctta atgaaattaa taatcccaaa gtcatacttc
    74461 caaagataga aaataattgt actcatgtat ggcatttatt tgttttacaa gttgaaaaac
    74521 gagatacatt tatggaatac ttaaagaaaa atggtataga gtctataata cattatccga
    74581 taccaccaca tctatctgaa gcatatgctt atttgggata taaaaagggg agttttaata
    74641 tagctgagaa ctattcagat aaagttgtta gtataccttt atttatcggt atggaagatg
    74701 aagaagttag ttatataatt aaaattataa atgaatatta aactactcat aataatatca
    74761 aaaataaatt ttttatatat catttattta aatttcgtta attgacattt ttaaatattg
    74821 atatattgta caaataaaat tgaaatatat ggaaaaatat agaattaaga tgagatttgt
    74881 cttatatttt tataaattaa aaatattttc aaagagttta ttataaaatt gtaaactata
    74941 gtgtttataa tctttgtaat tattggtaat taaatttaaa aaataaaata tttgattata
    75001 aacaaaaaag atatttaaaa aatttgttat ttattgtata cttaagttaa aactaaatag
    75061 gcaaatctag agaaatctag tgacgcaaag ctatagggac taaggtttgt atacacaagc
    75121 tatgtcagcc agttgccaaa aagagttcta agtatattgt atacgtagga agagtctagg
    75181 atgactgcct ttttggtggt cattttgtta tggaaaaaat cacaatattg tagtaaaaaa
    75241 cacctataat aacatatttt accaaatata atttaaaatt aagataaatt atctaaaaaa
    75301 gttactattt tacaaaaaat gacttcctta ttaatctaaa ttaattacat ttctactaca
    75361 ttaatataat aatgtatcac tttagtaaga aaactaatat tattttcgta aatcctaata
    75421 aaaatataaa aat
//
LOCUS       DAEORM030000015        74492 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.015, whole genome shotgun sequence.
ACCESSION   DAEORM030000015 DAEORM030000000
VERSION     DAEORM030000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 74492)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 74492)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 74492)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..74492
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.015"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            137..871
                     /locus_tag="KRH23_001380"
     CDS             137..871
                     /locus_tag="KRH23_001380"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HHS5224664.1"
                     /translation="MKQNKYDDDRFFNKYSKMERSTNGLAGAGEWHVLKKMLPDFKGK
                     RVLDLGCGFGWHCQYAVENGAISAVGVDISEKMLKEARNKTQLDNINYICMPIEDINF
                     PKDSFDVVISSLAFHYIQSFEDICKNISNCLSNKGNFAFSVEHPIFTAYGSQEWYCDK
                     DGNNLHWPVDRYFEEGVRKSNFLGEEVIKYHKTLTTYLNTLMKTGFEILEIIEPQPEE
                     KLLDTIPDMKDELRRPMMLLVSAKKR"
     gene            complement(1014..1505)
                     /locus_tag="KRH23_001381"
     CDS             complement(1014..1505)
                     /locus_tag="KRH23_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HHS5224665.1"
                     /translation="MNNQQQEVYKKLDELSIPYEAVNHPPVYTIEEMEELKTLHMEFV
                     VKNLFLRDAKGKEHFLVVLGKDKKADLKDIRQQIDSKPLSFASEERLQKYLKLTKGAV
                     TPFGILNDKEAVVKVVFDKDLLKMDKIGIHPNDNTATVFLKFEDMKKLIEENGNEIYY
                     VEV"
     gene            1854..2237
                     /locus_tag="KRH23_001382"
     CDS             1854..2237
                     /locus_tag="KRH23_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBECR2 nuclease fold domain-containing protein"
                     /protein_id="HHS5224666.1"
                     /translation="MSTDKVVGIIDEETAELAGIEYTGKIYASSGVIKHIKKKHRCQL
                     SKDIFNDIIDTIKMVLKSPEYIGSHPKKPGKSVEFIKKIDDYILVATELDTKKGYLYV
                     SSMYAIKEAKLESRVNSGRVKQYDG"
     gene            2744..3127
                     /locus_tag="KRH23_001383"
     CDS             2744..3127
                     /locus_tag="KRH23_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HHS5224667.1"
                     /translation="MNLSKKIEDKRKAKQRAEKVKKAKIATAGVVLGAVTGAVSGVLL
                     APKSGKETREDIKDASQQIAEKINMKTVDVKGKVSEKLEDKKGNFIESKKKIKKYIDN
                     KKSVENSSEEDKIIDIVEPVSVTEE"
     gene            3129..3479
                     /locus_tag="KRH23_001384"
     CDS             3129..3479
                     /locus_tag="KRH23_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224668.1"
                     /translation="MDNTITINISIIYVLLAILACIALVYLIIVLVKLHKILNNVGTM
                     LNENTQNINTTLNNLPNVVETFGEVGENMKDVTEVVTEVTADFLVTKDSVKSNMDVIV
                     DILTIIKNIFLDKK"
     gene            complement(3580..4038)
                     /locus_tag="KRH23_001385"
     CDS             complement(3580..4038)
                     /locus_tag="KRH23_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224669.1"
                     /translation="MIRTKVVELIATVCRENKPHKWVDENYTPYDKSGKVELMSIEDL
                     NELISSSGRADFLYSSRLQKLLNEVYINQSRASYISGCGLFWSSYWDILEEKFEEWLY
                     NSYIFFDEDDEYLEGMEDFELECKDVLMDVIETTSIDIYVQMIKRNITNY"
     gene            complement(4083..4871)
                     /locus_tag="KRH23_001386"
     CDS             complement(4083..4871)
                     /locus_tag="KRH23_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HHS5224670.1"
                     /translation="MKVVIIPGHTLIGKGTGAVGYINESKETRILNDLIVKWLKIGGA
                     TVYTGRVDESSTHLADQCAIANKQETDLAVQIHFNSNATTSTPVGTETIYKTNNGKTY
                     AERVNTRLATVFKDRGAKSDVRGLYWLNHTIAPAILIEVCFVDSKADTDYYVNNKDKV
                     AKLIAEGILNKSISNSQGGGENKVYENVIVYTGDADKVAAQILHWQLKDSLIIEASSY
                     KQGLGKKVYVVGGEANKLVKGDVVINGADRYETVKLALQEIDKL"
     gene            complement(5010..5447)
                     /locus_tag="KRH23_001387"
     CDS             complement(5010..5447)
                     /locus_tag="KRH23_001387"
                     /EC_number="3.5.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004132 - dCMP deaminase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006220 - pyrimidine nucleotide metabolic
                     process [Evidence IEA];
                     GO_process: GO:0009972 - cytidine deamination [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="deoxycytidylate deaminase"
                     /protein_id="HHS5224671.1"
                     /translation="MNKKLENRCSWQEYFMRLCETVAERGTCDRAYVGAIIVNSENRI
                     VSTGYNGSISGDKHCSEVGHEMRDGHCIRTIHAEQNALYYCAKEGISVKDCSIYVTHF
                     PCLNCIKAIIQAGIKHIYYRTGYRIDEYAIKLLQSSNVLYTKL"
     gene            complement(5681..5815)
                     /locus_tag="KRH23_001388"
     CDS             complement(5681..5815)
                     /locus_tag="KRH23_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224672.1"
                     /translation="MGILEGAAMIREIAIKIAKEKGITEQKAWPEAVKEFKEKYELVL
                     "
     gene            6269..6778
                     /locus_tag="KRH23_001389"
     CDS             6269..6778
                     /locus_tag="KRH23_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHS5224673.1"
                     /translation="MLSENIKTIRKSKGLSQQELAIKLNVVRQTISKWEQGLSVPDSD
                     MLISISEVLETSVSTLLGETIVESEVDNLKVISEKLEIINLQLAQRKNMRRKMFHWLF
                     ILLCAVIVIVFVVLGGLNSPYLDWNYTDPETAVFGVAFHAFEWLFVRLVPIVLIGAII
                     GIFLTRKKI"
     gene            6805..6951
                     /locus_tag="KRH23_001390"
                     /pseudo
     CDS             6805..6951
                     /locus_tag="KRH23_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005336078.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
     gene            7183..7719
                     /locus_tag="KRH23_001391"
     CDS             7183..7719
                     /locus_tag="KRH23_001391"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HHS5224674.1"
                     /translation="MQGGVNIRQVKSFVFPVISLIFLDQISKVLIGLFLMDFEIDIIG
                     KFLRFNPVQNTNLSYGGNFIGILSNLWVLVLFNLLVILVIISGYAFYKSKNEQTSYSV
                     KVIMSCGLAGTICSLIDKLFWGGSLDFLQIPSFLIFDLKDCYLTVAEIIFVVIGILHN
                     REISMKEYIYFCYPQFKR"
     gene            complement(8153..8953)
                     /locus_tag="KRH23_001392"
     CDS             complement(8153..8953)
                     /locus_tag="KRH23_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHS5224675.1"
                     /translation="MRLNKRSEGYINYVKGVKREKRNVLFYQLLILIGFIVIWELLAD
                     LNVINTFLFSKPSDIYNLFIQYAFSGQLFKHIGISVYETVLGLVIGTVLGILVAIALW
                     WSEKLSKILDPFLVVLNALPKTALAPIIIVWVGAGIEGIVVTAVTISVVVTILSAYNY
                     FMNIDEEKIKMLKSFGATKSQILFKLILPANTGNLINLTKINIGMAWVGVIVGEFLVS
                     RYGIGYLIVYGSQVFKLDLVMMGVFVLAICAWAMYAVVNIIEKIYNSR"
     gene            complement(9148..10746)
                     /locus_tag="KRH23_001393"
     CDS             complement(9148..10746)
                     /locus_tag="KRH23_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HHS5224676.1"
                     /translation="MKAAIYSRKSRFTGKGDSIENQIQLCIDYAKSIGVKDFLIYEDE
                     GFSGSNIDRPQFKKMMQDAKDKKFSYLVCYRLDRISRNVSDFSTLIEKLNELSISFIS
                     IKEQFDTSTPMGRAMMFISSVFAQLERETIAERIKDNMYELARSGRWLGGNTPHGFNS
                     EKITFLDENLKERSMYKLQVNDEQMEIVKLIYNKYLELRSLSKLYKYVYNNGIRGPRG
                     GKFDPSSLSRILRNPAYVKANDEILDYLKNSGMDVVGTPDRKCGILTYAKNTSNSIAA
                     IAKHHGVIEPEIWLEVQNQLDKNRDKTPRISTGKTALLSGLIKCGKCGSNMRITYKGK
                     KTDKDLKYYYICGTKKTLGSDSCNCKNLNGPLVESLVIDKIKNCKEESIISAFNNNNI
                     KTDNVFNIFKSETNLLKNQILDKEKLIKNLVIELAKNTGSTASDYIVSQIESLNNEIS
                     ILKDKINTLESSNINISSDSINIDIIVSNLKRFNDEVDNASLDDKRLLLSTIINSIVW
                     DSSLGNLNIVYMGAEVDNSVSLSN"
     gene            11074..11250
                     /locus_tag="KRH23_001394"
     CDS             11074..11250
                     /locus_tag="KRH23_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224677.1"
                     /translation="MEINVIEIFPKDKAKLNKIEMDKASWFVNIISKKYPKEALNEAF
                     STLEKELNISKANT"
     gene            11424..12554
                     /locus_tag="KRH23_001395"
     CDS             11424..12554
                     /locus_tag="KRH23_001395"
                     /EC_number="1.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004022 - alcohol dehydrogenase (NAD+)
                     activity [Evidence IEA];
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA];
                     GO_process: GO:0051144 - propanediol catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-propanol dehydrogenase PduQ"
                     /protein_id="HHS5224678.1"
                     /translation="MNNFEIKTRIKFGEGSLKALQELKNKNVLIITDPFMVKSKTIDK
                     ITSNLINSTYQVFEEIVPDPPIEVVVAGIESFKSINPDVIIALGGGSAIDAAKSIMDF
                     SKKILKINEVEFIAIPTTSGTGSEVTSFAVITDSQKKCKYPLVSDDLLPDMAILDPEL
                     VKTVPNFITADTGMDVLTHAIEAYVSTNSNDFSDALAEKAIKLVFKYLIKAYKDGNDI
                     EAREKMHNASCLAGMAFNQASLGINHSIAHVLGGKFHIPHGRTNSILLPHVIEYNSSI
                     VGYTNTTYSATAKKYAQIAELVGLGSANIRISVRNLVNEIKKLQKEMNMPTKLTQCKL
                     SLEDITNEEREIAKLAIKDTCTLTNPKVPTEDDIINILKNIK"
     gene            12795..13145
                     /gene="eutS"
                     /locus_tag="KRH23_001396"
     CDS             12795..13145
                     /gene="eutS"
                     /locus_tag="KRH23_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization microcompartment
                     protein EutS"
                     /protein_id="HHS5224679.1"
                     /translation="MTEESKQRVIQEYVPGKQVTLAHIIANPNEDIYKKLGLVLDKKD
                     AIGILTITPSEASIIAADVATKASNVSLGFIDRFSGSVVISGDVSSVESALNDVLEVL
                     GNMLNFSSAKITRT"
     gene            13153..13596
                     /locus_tag="KRH23_001397"
     CDS             13153..13596
                     /locus_tag="KRH23_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EutP/PduV family microcompartment system
                     protein"
                     /protein_id="HHS5224680.1"
                     /translation="MKNIIFMGKTGSGKTTLCQKLDQLELKYKKTQSVELYNNAIDTP
                     GEYMENRNLYNALITTSADAKIIAIVYDATQEENYIAPGFASMFCKDVIGIITKINKA
                     TENEVNIAYERLSLAGASQIFKIDTVDNIGLEKLFKYLEKYKNID"
     gene            13704..14279
                     /locus_tag="KRH23_001398"
     CDS             13704..14279
                     /locus_tag="KRH23_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ANTAR domain-containing response regulator"
                     /protein_id="HHS5224681.1"
                     /translation="MGKKILLVDDEPLLRMDTKDILESHGYEIIGEASDGFEAVEMCK
                     KHKPDLVIMDIEMPILDGIKAGKIICKENLAGGVLLLTSFEDKEYVEKAKSIGAYGYL
                     VKTASEKSLIPTIEMCLNKVNEFEKMKKDLEKVNSKLNERKLVERAKGILIREFKISE
                     DEAYTRIRKLSMDKRTTMMEIAKMIIIGYDD"
     gene            14272..15681
                     /locus_tag="KRH23_001399"
     CDS             14272..15681
                     /locus_tag="KRH23_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase N-terminal domain-containing
                     protein"
                     /protein_id="HHS5224682.1"
                     /translation="MTNTIKKISTAQTYLNNNEIEKIIEVSKSLDLMASFYEADVFID
                     VLSKFDDEAIVVAHGRPKEKSMYCENVIGKKALIENEPGVIKCLKTGERVRDIKALTQ
                     EYKLVKQNIQPITLDDKVLAVLIVEKDISSEVKNEFNASEDEENKNLHQFIKLIGNND
                     FLVDNLNSAILIFDKNGKLKIKNRIATEIYKNLGFGYDIQDMHYNDLDIETNTFENIL
                     MDENYDETNEVSIGNMFFKIKTIYIKDDEFKVCKIVQDISDLKRKEEELVLKTVAIRE
                     AHHRVKNNLHTVISIIKKQSRLSQNDEVKQCLDNIINRVFAILSTHYLLSKEVDNNIS
                     IREGINLLVSNIQGGYLFSKDIDIRITGEDFKISGEKATAILLVINEILQNCYDHAFS
                     DREHGTIQILINKDNDYRNIAIIDDGIGFDSNNINKNSLGTYIIDSYITQMLKGNIER
                     KSSENGTEVLITIPTQINI"
     gene            15865..17298
                     /gene="eutA"
                     /locus_tag="KRH23_001400"
     CDS             15865..17298
                     /gene="eutA"
                     /locus_tag="KRH23_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine ammonia-lyase reactivating factor
                     EutA"
                     /protein_id="HHS5224683.1"
                     /translation="MREELLSVGIDIGTSTTQLIFSKLIVENTESNFSVPRISIVDKE
                     IIYKSKVYFTPLISNNEINGQQIKDIVENEYKKANISKEDIHTGAVIITGETARKENA
                     NDVLHTLSGFAGDFVVATAGPDLESIISGKGAGAHIYSKEHSTTIVNIDIGGGTSNIA
                     SFKRGEVTDTGCLDIGGRLVKIDKISKKITYISPKIDKIIKDNNLNLQVGTMATVENT
                     KPIVDIMVDLLMESIGLKKQTPLFDFIITNKSISIDENIKNVSFSGGVADYIYYDGEI
                     KDYFEYGDLGILLGQAIKNCEYLKKVNVVKSMETIRATVVGAGSHTTEVSGSTITYTS
                     EKFPLKNLPVLKLSIDEETGTSKQISEAIKNKLNWFKLENDLQKVAIAMIGKKNPTFL
                     DIQEYAKGFVDGMQQIIENDLPFIVIVENDMAKVLGQAIYALLNYEKEIVCIDSVKVE
                     NGDYIDIGKPIVEGKVLPVVIKTLVFN"
     gene            17316..18680
                     /locus_tag="KRH23_001401"
     CDS             17316..18680
                     /locus_tag="KRH23_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine ammonia-lyase subunit EutB"
                     /protein_id="HHS5224684.1"
                     /translation="MILNTKLFGRTYQFKGLYDVMAKANEEKSGDKLAGLAAESAEER
                     IAAKVVLSHIKLEDIRNNPAVAYEEDEVTRIIQDAVNEKVYEEIKNWTVSELREWLLD
                     SNTTSLDIRRISRGLTSEMIAAVAKLMSNMDLVYAAKKIKVTAHCNTTIGEQGTLSAR
                     LQPNHPTDDPDGILASLLEGLTFGIGDAVLGLNPVDDSVESVTKVLKRFEEVKQKYQI
                     PTQTCVLAHVTTQMEAIRNGAPADLIFQSIAGSEKGNEAFGFNGDTIEEARQLALKHG
                     TATGPNVMYFETGQGSELSSEAHHGIDQVTMEARCYGFAKKYEPFLVNTVVGFIGPEY
                     LYDAREVVRAGLEDHFMGKLHGLPMGVDVCYTNHMKADQNDMENLAILLTTAGCTYFM
                     GIPHGDDVMLNYQTTGYHETASLREMFGLTAIKEFDAWMEKMGFSKDGKLTELAGDAS
                     VLLG"
     gene            18693..19574
                     /gene="eutC"
                     /locus_tag="KRH23_001402"
     CDS             18693..19574
                     /gene="eutC"
                     /locus_tag="KRH23_001402"
                     /EC_number="4.3.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008851 - ethanolamine ammonia-lyase
                     activity [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine ammonia-lyase subunit EutC"
                     /protein_id="HHS5224685.1"
                     /translation="MNEKDLKALVEQLVGQMVGELDTNVVSETVKKATEVVVDNNACI
                     DDITEVDIRKQLLVKNPKDAEAYLDMKAKTPARLGIGRAGTRYKTETVLRFRADHAAA
                     QDAVFSYVDEEFIKENNMFAVETLCKDKDEYLTRPDLGRKFSPETINNIKSKFGTNQK
                     VLILVGDGLSSAAIEANLKDCVPAIKQGLKMYGIDSSEILFVKHCRVGAMDHLGEELG
                     CEVICMLVGERPGLVTAESMSAYIAYKPYIGMAEAKRTVISNIHKGGTTAVEAGAHIA
                     ELIKTMLDKKASGIDLK"
     gene            19594..20247
                     /gene="eutL"
                     /locus_tag="KRH23_001403"
     CDS             19594..20247
                     /gene="eutL"
                     /locus_tag="KRH23_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0031469 - bacterial microcompartment
                     [Evidence IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization microcompartment
                     protein EutL"
                     /protein_id="HHS5224686.1"
                     /translation="MKNDVIRPNILGIKIISNISPEMAQKLELKSHHKSLGLITADCD
                     DVTYTALDEATKASEVDVVYAKSMYAGAANASTKLAGEVLGIIAGPSPAEVRSGLNAV
                     VDFLEYGATFISANDDDSIAYYAHCVSRTGTYLSEVAGIREGEALAYLVAPPLEAMYA
                     LDAAMKAADVKMCELFAPPTETNFGGALLTGSQSACKAACDAFAEAVKSVADNPTGF"
     gene            20258..20959
                     /locus_tag="KRH23_001404"
     CDS             20258..20959
                     /locus_tag="KRH23_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMC domain-containing protein"
                     /protein_id="HHS5224687.1"
                     /translation="MDAIGLIEVIGYVAAIEASDACLKSANVNIVRVDKVGAGIVTLT
                     ICGDVGAIKAALEAGEIAASRVGTLRTSHIIPRIHNEVTNALFKTKEPKVCEVSEDKE
                     KNFEITLEIADNVSKNLSEKENVILDVNENSGDTENLYSDIDKTNKKIETVDDSLTEA
                     NEEKIENTNDKEVLEQVKIENSDFDRDDLSKNSVKKLKAMAKKLDSSITYKDLNVLKK
                     EELINLVKKLSRRDR"
     gene            20962..22431
                     /locus_tag="KRH23_001405"
     CDS             20962..22431
                     /locus_tag="KRH23_001405"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetaldehyde dehydrogenase (acetylating)"
                     /protein_id="HHS5224688.1"
                     /translation="MTLLDKDLVSIQEVRTLVRRSKVAQEKLSKMSQEQIDKIVKAVV
                     DAAFNNATKLAKMANEETGFGKWEDKVIKNTFASMGVYETLKNTKTIGIIGEDKEANT
                     IDIATPVGVVAGLIPSTNPTSTVIYKTIISLKAGNTIVFSPHPNAKNCILETVNIISE
                     AAIKAGAPEDSILCITNPSIVGTNELMKHKDTNLILATGGEAMVRAAYSSGTPAIGVG
                     PGNGPAFIDKSANVKLAIKRIIDSKTFDNGVICASEQSIVIEKSMEETVLKELKNQGA
                     YVLNEEESERLAKFILRANGTMNPQIVGKSVEVIANLADLTNVPKNTKVLVARENKVG
                     HNVAYSREKLTPILAFYVEENVEAIMNRCREILLNEGAGHTFSMHVNDEELVKRFALN
                     MPVSRILVNTPSALGGIGASTNLVPALTLGCGAIGGSSTSNNIGPLDLINVKRVAYGI
                     KEIEELGRDKSQVEKSMFDSMDKEELINLLVQKLVKELA"
     gene            22527..22814
                     /gene="eutM"
                     /locus_tag="KRH23_001406"
     CDS             22527..22814
                     /gene="eutM"
                     /locus_tag="KRH23_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization microcompartment
                     protein EutM"
                     /protein_id="HHS5224689.1"
                     /translation="MASANALGMIETKGLVGAIEAADAMVKAANVQLVGKEQVGGGLV
                     TVMVRGDVGAVKAATDAGAAAAERVGELISVHVIPRPHFEVDAILPKVSAE"
     gene            22941..23702
                     /locus_tag="KRH23_001407"
     CDS             22941..23702
                     /locus_tag="KRH23_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin adenosyltransferase"
                     /protein_id="HHS5224690.1"
                     /translation="MGVLTENEVKRKIGKNKNNITEFYIEKGQIITPSAKSYLAERSI
                     ELKYVDKLSDVNNEPKEVVKEVVKEKKYKYTTVFGAKLDEKPEHMTQLNGNLLVFKDH
                     KRIILRGKIDSLESEILKVQILCQKLDMPKLVKELQEVLDFVRNIMRCEVLDEKLGDF
                     KLLGLTPQELREQSHYPKKYFGIGHEFPSYEMGEVVVAINSIRSNTREVELAAYEAFK
                     GEYGNVHREDLIKALNRLSSVFWIMIYKVRTNKYK"
     gene            23715..24344
                     /gene="eutD"
                     /locus_tag="KRH23_001408"
     CDS             23715..24344
                     /gene="eutD"
                     /locus_tag="KRH23_001408"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization phosphate
                     acetyltransferase EutD"
                     /protein_id="HHS5224691.1"
                     /translation="MENLLNEIVEEVITRVKKEAFIEVEASGRHVHLSREDVDKLFGE
                     GYTLTKLKDLSQPGQYACKERVTITGPKGSIKNVVVLGPCRNETQVEISLTDGSTLGL
                     KAPIKQSGDLEGTLSIKISTQYGEVELDKGLMVAKRHIHMTPKDAEKFNVCDKEIVEA
                     KVMGQRPLTFDDVVIRVSDSFKTYMHIDYDEANACGYSKGTVAKIIKKA"
     gene            24386..25111
                     /locus_tag="KRH23_001409"
     CDS             24386..25111
                     /locus_tag="KRH23_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02536 family ethanolamine utilization
                     protein"
                     /protein_id="HHS5224692.1"
                     /translation="MNYDNLVDLITEEIYKKINSNEIKISNKPKAVIVFEQDNNKFNL
                     LKDEFEIVEFDKSIRECEIVIVSRLCMRGLSNIALGNSTSDEERFILKMIMKGKKVYV
                     LDEGIEYKKYKDTAPKALYKKFMSFEDEICKFGVEIVKDLNVITKNKLNIKKELESTR
                     GSKKEDTKVLDKDVLNLTSVESVKIDNEFSLDLRNKKLISEADLRKPTINGVKNILVN
                     KKSIITPLAVDFMRIHHLKLKKV"
     gene            25124..25396
                     /locus_tag="KRH23_001410"
     CDS             25124..25396
                     /locus_tag="KRH23_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EutN/CcmL family microcompartment protein"
                     /protein_id="HHS5224693.1"
                     /translation="MDIGKVVGNVWATRKDEKLCGQKLLVVKILKTKDTYKEGFMVAA
                     DNAGAGNGDLVLISKGSSARESIEKSHVPVDATIVGVVDSFEVFDE"
     gene            25389..25940
                     /locus_tag="KRH23_001411"
     CDS             25389..25940
                     /locus_tag="KRH23_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0031469 - bacterial microcompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BMC domain-containing protein"
                     /protein_id="HHS5224694.1"
                     /translation="MNKSIGAIEFKSIAKGIEVSNEMIKKSSVDVLYLKSICPGKFLI
                     IVGGETSYINGCVDYGIKLGEGYIVDNFVINAISQEILDGFKNKYQKLDSIVSIGVVE
                     SSKVCAGIKMLDKTLKSGDLVLVKLQLSFAIGGKLVYIVAGDLSSLEYSLKESENVVR
                     EKEVIYKTVIPSVDSQIIKSLIK"
     gene            25952..27043
                     /gene="eutH"
                     /locus_tag="KRH23_001412"
     CDS             25952..27043
                     /gene="eutH"
                     /locus_tag="KRH23_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization protein EutH"
                     /protein_id="HHS5224695.1"
                     /translation="MSINEIIIYVMVVFMVLGAIDKCIGNKFGLGEQFEEGIMAMGSL
                     AVAMVGVICLAPVLADVLRPIVVPVFNILGADPAMFAGSLLANDMGGAPLALELAKDP
                     NAGLFGGLIVGAMMGPTIVFIIPVALGIIEKEDQKFLATGILAGIITIPIGAFVGGLV
                     AGFEVMMVLRNLVPIIIFAVVIALGLLKFENAMIKGFTYFGKGVVIVITLGLAAAIVE
                     ALTGIVVIPGMKPISEGIEIVGDIAIVLAGAFPLVFVITKVFNKPLMALGKVLGMNDV
                     SAAGLVASLANCIPMFGMMKDMDNRGKIINVAFSVSAAFVFGDHLGFTAGFNSNMITP
                     MIVAKLVGGITAVLLAMVIANKTLKKENV"
     gene            27045..27518
                     /locus_tag="KRH23_001413"
     CDS             27045..27518
                     /locus_tag="KRH23_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HHS5224696.1"
                     /translation="MDISNIDKNLIETLVRQIIEEKISGTKDTVDFVRNKDISGITSI
                     KLPTVKVSESDRLDTGNPSDVVYTKDLFTLEESPRLGCGMMEMKETTFDWTLNYDEID
                     YVIDGTLDIIIDGRKVSASSGELIFIPKGSKIQFSVPDYARFIYVTYPADWASQN"
     gene            complement(27618..28085)
                     /locus_tag="KRH23_001414"
     CDS             complement(27618..28085)
                     /locus_tag="KRH23_001414"
                     /inference="COORDINATES: protein motif:HMM:NF024242.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HHS5224697.1"
                     /translation="MSILEMFSEYSKQDRYYNNILNHLIMVFFAKLLRGYENSIEVPN
                     MTKKDNLKNTHILTYIQDNYFDITLEELANEFHFSIPYCSKIIKEIAGCNFTQLLQRI
                     RLERAESLLINTNISIADISNNVGYPNVEHFIRLFNKKYNMSPSKYRKNTSKI"
     gene            complement(28161..28766)
                     /locus_tag="KRH23_001415"
     CDS             complement(28161..28766)
                     /locus_tag="KRH23_001415"
                     /EC_number="7.6.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHS5224698.1"
                     /translation="MNDNIVEVKNINMNFYTKEGELEVLKDVNFNLKEGEILTLLGPS
                     GSGKSTILNILTNLLKPTSGDIKITGNIGYMFQKDNLLEWRNIMDNITIGLEIQGKKD
                     KKSLDRVESLLKTYGLWDFRSMYPKELSGGMRQRVALIRTLSVNPDILLLDEPFSALD
                     YQTRLLVCDDVYSIIKNENKSTILVTHDIGEARCIKVQHKR"
     gene            28936..30294
                     /locus_tag="KRH23_001416"
     CDS             28936..30294
                     /locus_tag="KRH23_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224699.1"
                     /translation="MSNIITNLIESIFTNPITILFLLAITVYSVFKIIENNRVYSFVS
                     SKLDEINRDYKTSEFYKKVRDDYYTYSKENPYADVNITSFIEEVVSDLKHNNLPLLEK
                     IRSIKNSSSISILLGVLGTFVGLSTMLLCVDTKDIINSLPSTISSMQTAFTTSIFGVV
                     FSLIIGYFTKIKDCEHVLIQIMLKSENLLTSEITHFKSERMDLKVEEVKNTIKQISKS
                     IEAIEKFDKISKDLNDFNDEFISGIEALKSLLEGSQSSIKTFDQSVRKLDKQFNILNI
                     KFVKLFDKYDNQDNINKEILFDIKESSKNIYNATESQFKIRDYIKNINAGFALYERSA
                     QDLLTKLMTHENKISQNQKILLDEKFTLDDSIKNLSSIIENFSNDLQVKLDMMFENSL
                     DIQDKLDVMFNNSFMNDEVPLDSEELFKDDVNNVFNPFSEEIYEIEDKEIKVIGEDEL
                     NE"
     gene            30287..30919
                     /locus_tag="KRH23_001417"
     CDS             30287..30919
                     /locus_tag="KRH23_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family protein"
                     /protein_id="HHS5224700.1"
                     /translation="MNNKYRRTVNREFEKSSFWPTFTDLLSTVLMVVILILFSSESIS
                     GSVEQDLAKNVNASVEETFKKSGIPVKVDKSNGQVTFGEKTMFDVDSDVLKPEAKEML
                     KMFVPKYIETIYKDYGDYISKIVIEGHTDDVGSYIYNLDLSQRRAYSVAKFIVGDEIG
                     DYKYKDKVTKHIIAIGRSKAELIKNGDNSVNRDASRRVELKYEININQNK"
     gene            31248..32405
                     /locus_tag="KRH23_001418"
     CDS             31248..32405
                     /locus_tag="KRH23_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0030420 - establishment of competence for
                     transformation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ComEC/Rec2 family competence protein"
                     /protein_id="HHS5224701.1"
                     /translation="MIEISIKNKKNSKIKTLILLLIVSISIYLTGCTTSDNGNNQSNN
                     NDSLSSSISSDKNVKIHFIDTGNSDAILIQDGKTFILIDGGDNDDEGLMVDYLNNQGV
                     KDIKYLIATHSHADHLGGLDSVVKNFNIENVFVSNGSAETKSYRDFINALANKGLSPS
                     VPLENNKFYLEDSYFEVLNTNGGDTTNEQSLVLVYTNGNDKVLFTGDAEEGTEKEILP
                     KLEKVDLLKVAHHGSRSSSSQEFLDKVNPEYAVLLVGKGNSYGHPHQETMNKLKKMGV
                     KVHRSDECSDIIFESTGDGVFTSCKDGSYNKGVREDGNSGKSNSNTSKNDSFKNKQNT
                     SNSEEIVYFTPKGKSYHSTKNCSGLSRSKKILSGTIAESKKNDPCDICYGK"
     gene            complement(32552..33187)
                     /gene="lexA"
                     /locus_tag="KRH23_001419"
     CDS             complement(32552..33187)
                     /gene="lexA"
                     /locus_tag="KRH23_001419"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0009432 - SOS response [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor LexA"
                     /protein_id="HHS5224702.1"
                     /translation="MYLDLTEKQVLILEFIKSQIILKGYPPAVREICTAVGLRSTSTV
                     HSHLNKLEKLGYIRKDPTKPRAIEVLERSKVNDVSGANQEIIELPLVGQITAGEPILA
                     QQNIEEYIPFPASLVKGSNNFVLRVKGESMINAGILDEDYVVVDKKNTALNSQIVVAL
                     INGESATVKRFFKEGNLIRLQPENDFMEPIMLNDSEVEIVGIVTGVFRVIK"
     gene            complement(33291..34418)
                     /locus_tag="KRH23_001420"
     CDS             complement(33291..34418)
                     /locus_tag="KRH23_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009009 - site-specific recombinase
                     activity [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HHS5224703.1"
                     /translation="MNNDKKIIKVHNKSDKPDNIVIKENELIEKCLLLENKLPVFMKD
                     YFIYLKGSVAVSTRLAYLEDINFFCSYLIETKELTNADCVKDITEDDFNTIKSRDINL
                     FLGDYCSRYYKNTEKNTLIFENNNRALARKKSSISTLFKFLYRNSQIDNNITDGFNPI
                     KLPKPQPDAIKRLEIDEVAKMLESVETGEGLTEKEKVYWRKTKLRDKAILALFVTYGL
                     RLNELRELNISSFNFSRGEFKIYRKRGKEVLMPINHTCEHVIKDYLQNERTRDELLND
                     EEKDALFLSLQNKRITAKAIRTLVKKYTSIPLDTTRDNGYSPHKLRATAATSLIQTGF
                     SIYDVQNLLDHDNVTTTQLYAAHKKNVKRDIVKNFEWIEDD"
     gene            complement(34739..35584)
                     /locus_tag="KRH23_001421"
     CDS             complement(34739..35584)
                     /locus_tag="KRH23_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224704.1"
                     /translation="MIYIIEILKISVINIFCFIGIFIVFGLIFSITENLNNKFIFSSF
                     GKTGIIVTGAIGTFVHELSHLIMCLIFMHKINSVKFFRPIESKNDGILGYVSHSYKKD
                     NLYQSIGNFFIGIAPIIGGTIMIILIFKILLPDSYMKVTQNIDLKLYVSMINNLNING
                     FIHIILGDISNFIRIMLLTPSVYSLKYFIFMFLMYSISTHMSLSSADLKNSLNGLSFI
                     VIVIFVISSITYLFGFDNLNISSLIVKYNIFISFFMAIGFIFSIVTLIISYILSLVSP
                     FKNFS"
     gene            complement(35614..35985)
                     /locus_tag="KRH23_001422"
     CDS             complement(35614..35985)
                     /locus_tag="KRH23_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HHS5224705.1"
                     /translation="MKLKLLVEEYAVCRLNNDSKIPTWIDTEKFYSITRTDDELSVVC
                     LNNNIPSDVKSEKEWRILKILGPLDFSLVGILSKLSSLLADNKISIFAISTYDTDYIL
                     VKEKDIENACKILSCNGYEVE"
     gene            complement(36138..36398)
                     /locus_tag="KRH23_001423"
     CDS             complement(36138..36398)
                     /locus_tag="KRH23_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003866776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein S"
                     /protein_id="HHS5224706.1"
                     /translation="MEVLKVSSKSNPNSVAGALAGVLRERGVAEIQAIGAGALNQAIK
                     SIAIARGFVAPSGMDLVCIPAFTDIEIEGDKKTAIKLIIEPR"
     gene            complement(36587..37531)
                     /locus_tag="KRH23_001424"
     CDS             complement(36587..37531)
                     /locus_tag="KRH23_001424"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit alpha"
                     /protein_id="HHS5224707.1"
                     /translation="MIENNSEKIKVLENDIKQLITISKANNIDLSDKINSLNEKLEKL
                     KEDAFSHLSAYEKVTLSRDIKRPTTLEYIEHICSNFLELHGDRLFKDDPSMVGGIGQI
                     GKFNVTIVGHQKGRDTKENIKRNFGMPHPEGYRKALRLMKQAEKFNRPIITFIDTSGA
                     FCGLEAEERGQGEAIARNLLEMSKLSVPVITFVIGEGGSGGALGIGVGNDVCMLEHSV
                     YSVISPEGLSSILFKDSSKAKEACDVMKLTSNDLYDLKIIDKIIKEPLGGAQKDVEAV
                     SKEIKAYILERLNHYKDMDKEEIIAQRYKKFRNIGKCL"
     gene            complement(37552..38406)
                     /gene="accD"
                     /locus_tag="KRH23_001425"
     CDS             complement(37552..38406)
                     /gene="accD"
                     /locus_tag="KRH23_001425"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase, carboxyltransferase
                     subunit beta"
                     /protein_id="HHS5224708.1"
                     /translation="MIKKFLSSKESKYVTISLDDNFKKNSVDDKFWTYCKGCDSHVFR
                     KDIEENSFVCPKCSRHYGLRARKRINLLIDKGTFMEFNSDVEFQNPLNFPKYKEKVDS
                     YKEKTKESEAVVTGYGRINGIKTVICVMNPDFMMGSMGSIVGEKITYSIEYAAENNLP
                     IIICSASGGARMQEGMVSLMQMAKTSQALSKLEEKSLPYISVLTDPTTGGVTASFAML
                     GDIIISEPNTLIGFAGPRVIEQTINQKLPEGFQTSEFLLEKGFIDMIVDRRKMKEVLY
                     QILAMHKK"
     gene            complement(38421..39782)
                     /gene="accC"
                     /locus_tag="KRH23_001426"
     CDS             complement(38421..39782)
                     /gene="accC"
                     /locus_tag="KRH23_001426"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0004075 - biotin carboxylase activity
                     [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HHS5224709.1"
                     /translation="MIKKILVANRGDIAVRIIRTCKELGIKTVAIYSEIDKDCFHRYI
                     ADESICIGPNNISKSYNNIENIIYLALKLKCDAIHPGFGFLSENPEFAKQCEDNNIIF
                     IGPTREQMILMGDKSRARETMMELNIPVVPGSESVLKTKEEALEVAREIGYPVMIKAS
                     SGGGGKGMRIVRKEEELFSNFDMASSEALAAFSNSDLYMEKFIENPRHIEVQVFGDKH
                     SNAIHLGDRDCSMQRRNQKVIEESLSPYLSDEERQKLHKIAVDIVKGVGYIGAGTIEF
                     IVDKDKNFYFIEMNTRIQVEHPVTEMVTNLDLIKLQISIANGDKIPFKQEDITFRGHA
                     IECRINAEDSSKNFAPSPGKIESLNLPGGFGVRFDTFVYAGYTIPPLYDSMIGKLICW
                     AETREECISRIYRALDEIIVEGINTNVEFQKALVTSEEFREDTHHTKFIEDVFMKKEF
                     ATL"
     gene            complement(39798..40250)
                     /gene="accB"
                     /locus_tag="KRH23_001427"
     CDS             complement(39798..40250)
                     /gene="accB"
                     /locus_tag="KRH23_001427"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HHS5224710.1"
                     /translation="MNINEIKELLKAIDSTNLEYVKLESSDLRLEVSKKAQSTSSPVL
                     SVQQESVVDLSLEKPVVNDTPVTSNENLSVVVAPLMGTFYDSPSPDADSFVKVGDVVE
                     EGDTLCILEAMKLMNEITSEIKGEIIEVLVSNEELVEYNQPLFKIKPL"
     gene            complement(40520..40966)
                     /locus_tag="KRH23_001428"
     CDS             complement(40520..40966)
                     /locus_tag="KRH23_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224711.1"
                     /translation="MESKFFNWYTQSLGGTFGIISCICAYLNGYMFVYTNSASKYFES
                     IGFLGIISSYTLLPLCMLTLIFGVIYSYTPETSDKSIFNIPFFTLNKRLILITVVFGF
                     IGARVYFIIPAILITFNLYSNVLIAKLKYILCKNKENDTNLKESEV"
     gene            41241..41519
                     /locus_tag="KRH23_001429"
     CDS             41241..41519
                     /locus_tag="KRH23_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224712.1"
                     /translation="MVDTLEFGLKILFFILSIIWMGKIMILRTDKQIVINPLLIGISA
                     VLVMLHTSQSNIEFFGLDVQYIRIVLYIIYSLIILIGIWATNRRNGIF"
     gene            complement(41648..42379)
                     /locus_tag="KRH23_001430"
     CDS             complement(41648..42379)
                     /locus_tag="KRH23_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224713.1"
                     /translation="MNLANLIPFIISAAALSPINSNDKVLSENQLKDIFPDANLRAVV
                     KRYINPDEMTISNIKALDGEFYATGESISNLKGISYLENVDNFIFWNNNIKEVPKEAL
                     SLKDMDSINLANNYLIDDDVVNSLSHNGVDVNCDLNFIDTKDNQYKLDSKYHNVDIAK
                     GESIDLRKIITKKIDSYYKYWEVTDNLPKDLNFIVSVSDKSVLSCEDMIIKGNKTGQA
                     VVKVILSDKNDLNTSQEVLITVNVK"
     gene            complement(42523..43167)
                     /gene="trmB"
                     /locus_tag="KRH23_001431"
     CDS             complement(42523..43167)
                     /gene="trmB"
                     /locus_tag="KRH23_001431"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008176 - tRNA
                     (guanine(46)-N7)-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HHS5224714.1"
                     /translation="MRRRRKKGSDEKLLSYTKYVLRDDIDKLKGKWNLKFRNDNPIHV
                     EFGTGKGKFITTLAKQNPDINYIAMELKEEVLLKAVEKADASNLNNILFLWGDVSNIL
                     DYFEAKELSRIYINFCDPWPKNRWSKRRLTHSGFLEMYNRVLEDDGEIHFKTDNEKLF
                     EFSLNEIAANNWLLKNISLDLGNSEYENNVTTEYEDKFMSQGMRIFRCEAKKRN"
     gene            complement(43305..43625)
                     /locus_tag="KRH23_001432"
     CDS             complement(43305..43625)
                     /locus_tag="KRH23_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein HesB"
                     /protein_id="HHS5224715.1"
                     /translation="MKITLPETAIDTLKSILKDNQDKPNNIRVYFAGVGCGGPSFGLA
                     LDEKKEDDLTYEVGELQFVMSSDEYSQYGDIIIEDTGFGFRVIPENMKDQGGGGCSGC
                     SGCH"
     gene            complement(44078..44326)
                     /locus_tag="KRH23_001433"
     CDS             complement(44078..44326)
                     /locus_tag="KRH23_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HHS5224716.1"
                     /translation="MQKTKAWGIIEPEKPESQQQMAHMDFAVNDLKEAVQYAIHCGAT
                     IAEEQFTDDWRVMIDPAGHPFCLCQMKSIMESSHFSLL"
     gene            complement(44357..44818)
                     /locus_tag="KRH23_001434"
     CDS             complement(44357..44818)
                     /locus_tag="KRH23_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HHS5224717.1"
                     /translation="MKFGGVLLIVKDINKSKKFYEDVMEQKITLDLGEHVSFENGFGL
                     QSNYKAIIGYDLPIYQQSNNFQLYFEVNDIKQWESKINRIGNIEFLHYIKEYPWGQRT
                     FRFYDFDKNIIEISESMESVIKRLLKQGLALEEISKRTMYPVEFITQFQQL"
     gene            complement(44856..45689)
                     /locus_tag="KRH23_001435"
     CDS             complement(44856..45689)
                     /locus_tag="KRH23_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHS5224718.1"
                     /translation="MLKKESIHFINKNRSLIVCEDNFVYLLPCIQLRNWISNFTISFP
                     NQTIISDNYTIIPHGSVTLVFFYDATGLHSLLFGPTTKPKTVGNIANRCDVILIIEFQ
                     PAGFFPLIGIQQSELIDKVVPFSIINTSLDLEIKKIFNESLSIDKLILKLEELLISNI
                     KIEYSYEFILAIQLIIQNSGNISSQEISKKVFYSSRHLNRLFNQYLGLSMKSFSRLVR
                     INKSIKLLNNNKTSLMSICNELGFYDIPHFIKDFKIVCGITPQKYRANMSDFYSEIAK
                     F"
     gene            complement(45963..46649)
                     /locus_tag="KRH23_001436"
     CDS             complement(45963..46649)
                     /locus_tag="KRH23_001436"
                     /EC_number="7.6.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHS5224719.1"
                     /translation="MKITHNSLAVEAKNIIKEYKIGNTTTRVLKEVSLQVMKGEFVSI
                     MGQSGSGKSTLLYILGGLDTPTSGKVYMNGADISHFNDEKMSIIRRRNIGFVFQFYNL
                     IPNLNVEENIMLPLLLDGKNLKDYKNQLDEILDIVGLTDRRKHTPRELSGGQQQRVAI
                     ARALIGKPEILFADEPTGNLDSKTGIEIIDLLNKINRDNGQTIIMVTHSPEAAKSSSR
                     TITVSDGLIV"
     gene            complement(46664..49141)
                     /locus_tag="KRH23_001437"
     CDS             complement(46664..49141)
                     /locus_tag="KRH23_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HHS5224720.1"
                     /translation="MKIILKYIFTNIKERKIRTAVMLLSIVLSTVLLFVSFSIGLSYE
                     SAQRKMAKGMYGTATISVQSKNPDILTNLEDIPDLNAIKSKVGVLESSAIYNKGGYYE
                     EFSLISADLSQLNKINKPRLENGDSITDFSGDKIILPNRFTSKYKIKKGDSITLQIYG
                     KSYTFQVSDIASYDTVFLRNTRGVNALLPKETLSKIINKGSGYTRVLIESEEEITENL
                     VNKLSEELSTEKYMVSNTINETKIISDARQKTMPFFLISFFALTLSIFIIYSSYKVIT
                     LERLPFIGTFRSIGANEKTVTRILMLESILYGSIGGLIAIPIGVVVLNLMLHGLGNSL
                     EQGISIPVVISPIGVIISVIVAIIVSSFSAYIPVKKASHLPIKNIVLGTVEEKNVSNR
                     SILFIGSIMFILSILLPRISPENTLYLAGGFSLLGLIVATIVLIPLITDIMSIVFEFV
                     YKNILGNEGKLAARNMKNNKNIIQNITLLFISISAVIAISVVGNFVKTYITDVFRDAE
                     LQGFADGKMNEEFIEDVRHMDGIKKILPLYVMNNEISGNGVTLSRLEGTDNIKLYNSM
                     FGINYTNFEIKKQVIEAFNDKRSVILNEDTLKKVGLSIGDTITLSNDKYDFSYKIVGS
                     FKSRANDVEAVIPSHYAVNDFDKTNYGFLVYTAVNPDAVMIQIRYLFGDTYNWSRTVE
                     EFNNDSLNTISSFLSPMNKMTYFIFLLATVGIINNLLINYIQKRRSIAMYKSIGLSDK
                     QNIKVTLIEGFTSGLLGAVIGIVISILEIQTIFIVAGPKISMKPDLDFKTFIIVGLLG
                     IIVTLIGSIVPIIKGKKMKLIEEIKFE"
     gene            complement(49360..50712)
                     /locus_tag="KRH23_001438"
     CDS             complement(49360..50712)
                     /locus_tag="KRH23_001438"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HHS5224721.1"
                     /translation="MIFICLILTVIGIFLSLITIQKPNGEFIRSDWPKKFTENFNEQI
                     VFIDNKPQVKQSGLEKLRENQLWLQILDSSGNRVYGFLEPKEHKDYYSNSELLALANQ
                     NNSSNGTVYFNTIKNNKNDYIYIIYFPLNISKVNMFFDGGKFIGGKSIVFSIIGIIFL
                     IILVSGIAYGYWVTKCISNITSAVSDISKRSYLPVNIKGVFADIYNSLNILNEEIHKS
                     DEIQNKTDIMREEWISNITHDLKTPLSPIKGYAELLTDSSTNYSPEKVYKYASIMLKN
                     IEYTNTLINDLKLTYQLKNGIIPLNKNNYDLVRFLKELSIDILNYPEYESNIVEFKSN
                     IDNINFDFDCTLLKRAFSNLIVNAFTYGDKNTKVCVHVKLNERIEIIISDNGKGMSRE
                     EASNLFNRYYRGSNTKQKIEGTGLGLAITKQIIEVHGGNISVESIPGLGSSFYITFPI
                     "
     gene            51262..52122
                     /locus_tag="KRH23_001439"
     CDS             51262..52122
                     /locus_tag="KRH23_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HHS5224722.1"
                     /translation="MKKQKSPILLEMLGLFFGCISMSIGINMFLKPHTIAPGGLSGLS
                     LVLNKVTGLPVSAIMLIIGVPLVILAFRIMGTKNSLKTLFGTVVFSAIVQLTDPLSKL
                     RFTNDLLLSSIAGGILVGIGLGIMFKSDASTGGTDLIALILSKKFPGIKATKFMSCLD
                     GMVVISSGIVNRSLETALYSGIALCVLIKIADMIMEGFDHSKAFFIISDEPESLRQAI
                     TEELDRGLTILDGKGGYTRENKEVLLVVVSKKQELYLKRLVKRTDPTAFVIVTDVHEV
                     LGEGFKNLEN"
     gene            complement(52361..52918)
                     /locus_tag="KRH23_001440"
     CDS             complement(52361..52918)
                     /locus_tag="KRH23_001440"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HHS5224723.1"
                     /translation="MSDSEYPQMKTLETRSCILRPASLDDVEDFFDCYKNKIVVKHLP
                     FSEHKSLEDTRKFIKSFFLNPYKKGKIGHFAIVYKRDNKVIGNMGFNNINPKALEAEI
                     GICINPSYWGHDFATEITKRVIQYGFRELNLNKIIAITYEENQNSTKSLDLLGFKCTG
                     KYIKKIHTGNTVKNVPCYQYELKKQ"
     gene            complement(53108..53995)
                     /locus_tag="KRH23_001441"
     CDS             complement(53108..53995)
                     /locus_tag="KRH23_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HHS5224724.1"
                     /translation="MNIKLELYKVFNAVVNNKSFSLAAKELFMSQPAVSQSIKQLEEQ
                     LDTLLFYRNNKGVKLTPEGKILSEHVTTALKLISSGEDRINKFKKLEYGSLKIGVGDT
                     AARFFLLKYLEIFHKKYPHIHVSTINRTSRELISLLKDGNIDIAIINMPIEDDTLNIV
                     ECIEIHDIFVCANDYIEYKGRKISLEELNTLPLIMLENKANSRLYVNEYFLSKGIKLN
                     PDIELGSHELLLEFAYINLGVSCVIEEFSIDYLENEKLFKLDIKEPIPKRNIGYCHLK
                     DISLSLATKEFLSMISNNI"
     gene            54114..55313
                     /locus_tag="KRH23_001442"
     CDS             54114..55313
                     /locus_tag="KRH23_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003493023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="coenzyme F420-0:L-glutamate ligase"
                     /protein_id="HHS5224725.1"
                     /translation="MDRLVGTVSRGVRAPIIRQGDDLVKIVVDSVLNASKSENFEVRD
                     KDVIAVTEAVVARAQGNYAHVDNIAKDVKDKFGDDTVGVIFPILSRNRFAICLKGIAK
                     GCRKVVLMLSYPSDEVGNHLISIDELDDKGINPWSDVLTEEKYRELFGYNKHTFTGVD
                     YVDYYKNLIKDCGAEVEIVFANNPKTILNYTTSILTCDIHTRQRTKRILRQNGAKKVY
                     SLDDIMTASVDGSGYNDQYGLLGSNKATEETVKLFPINCDEVVNKIQGNIKEITGKDV
                     EVMVYGDGAFKDPVGKIWELADPVVSPAYTKGLEGTPNEVKLKYLADNDFADLSGDEL
                     KEAISKYIVEKDNKSDDLTGNMVSQGTTPRRLTDLIGSLADLTSGSGDKGTPIIYIQG
                     YFDNYTK"
     gene            complement(55507..58062)
                     /locus_tag="KRH23_001443"
     CDS             complement(55507..58062)
                     /locus_tag="KRH23_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HHS5224726.1"
                     /translation="MMSLVKFSIQYIKHYKKQSISIVLSIVLSVALLTGIGSLVHSAD
                     KSRIEKIREDSGDYHYFYKVDKEQLNKIKKNKKSKEYTVDRLGVTKPKNQIDEPFIIE
                     FLNADSSYLDMTGRKLLKGTLPSKDGEIVLDTYSLNNLNVNKEIGTEINLDGKIYKLC
                     GILSSLSNPETAMEGFVNDYFQPKEKDSYIVYVKYDENKNIKKQNYKFMKKFNISKEK
                     TYINWPLSVEFGVKPPKNIEKYNIFEFLKNLELNTNAIILLVGVFGAAAVYSIFHVSI
                     LQRISQYGVLEVLGANNKQLLFLLFLELFLLFIVGFPIGCFLGIGVASTIYEQFPHIF
                     LSSDIVPGAFFISEKSIYLGFLFILLLLILIAVRVVHQLNKYSSIESMKNFKITNKKK
                     RILESVKHSNMTKVLSHKYMTQKKGMFIGILFSLSLGGIIFLCSSYSIQLTKNNNELT
                     MKADDGLNSDYQITMQTTDFDVGIPKDKISRLNNVEGISKVYPVRYLFGAMQIKEEQL
                     FWKNFFKPLEKDYRIKTFFDGICTKQNEGGYLLKTNIYGYNNGMLEGLNSYIIDGEIN
                     THDMVKNNKVIVRLPMDGTGMYDAVDINPGDTIKVKVPKTMKPTDEIVKFKEENKNDY
                     TTKEFVVAATVKRVMANNIYFIGDYGMDIVMTNGQMKNNFDIENYNSVSIKKTEDSNS
                     EELSENIKSVVSDVKRCIVTDYTIAIEKNNTYLNQKLLFIYGIVFVLLAISLFHIINT
                     VSYLIFSRRHEFGILRAMGITDNKFLLMMIREGFLYGFYASIIMVIGSVIGQFMIYFM
                     VKRVYLYINPILKINTPLYIGMIILNITISIVAVIIPVRQILKSDIISEINKN"
     gene            complement(58059..58745)
                     /locus_tag="KRH23_001444"
     CDS             complement(58059..58745)
                     /locus_tag="KRH23_001444"
                     /EC_number="7.6.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHS5224727.1"
                     /translation="MSILVTNNLVKHYGKGETKVKALNGVSIEIERDTFTAIVGTSGS
                     GKSTLLNIIGGLDNPTSGDVIIKGKNISKIGKKDLTVFRRRNIGFIFQNYSLMPVLNT
                     YDNIALPVTLDKGNHIDHEYIEMLMKTLGIWDKRLKFPSELSGGQQQRVAIARALANK
                     PALILADEPTGNLDSKTTMEVVCLLKESSAKFHQTILMVTHNENIAQVCDSIIHIEDG
                     VVVNTGGELL"
     gene            complement(58822..59730)
                     /locus_tag="KRH23_001445"
     CDS             complement(58822..59730)
                     /locus_tag="KRH23_001445"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HHS5224728.1"
                     /translation="MFILAFIICTVVIFIVSTKINQRRYDELNLMLNQILEGKEVTYP
                     DTKDTRASKISHQVKKIKDMIEIEVEQSKSEKEAIKGLISNMSHQLKTPLSNITIYCE
                     LLENINISTLQKKEFLQKMKNETFKIDWLLQSLFKMTKLEDGVIEFEVEELLIKDTLI
                     QSISTIFNKAEAKNIRINLEPFSDIKLVHNKKWTIEAIVNVLENAIKYSPSDSTITIS
                     VIKMELYTKITIKDEGIGIDSRELNDIFKRFYRSKNVENQNGTGIGLYLTRLILEKEN
                     GNIIVESKLGSGCCFSIFLQNCKSLN"
     gene            complement(59732..60403)
                     /locus_tag="KRH23_001446"
     CDS             complement(59732..60403)
                     /locus_tag="KRH23_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HHS5224729.1"
                     /translation="MNLLIIEDDINLNEGLFYAFENDGFNVFKAYTKQEGLNIFNSKN
                     IDFIILDCNLPDGDGFDVCQIIREKSDIPIIMLTARDSEIDEVKGLEIGLDDYITKPF
                     SLSVLKARVKVAIRKKSNNKVIYSNGIKLDQKLLKVYKNKECLELSSVEYKLLSYLIE
                     NKGQILLKEQILHHIWDSEENYVDDNIVSVNIRRLRVKVEDDPSNPKYIKTAYGMGYL
                     WNEVE"
     gene            60665..61729
                     /locus_tag="KRH23_001447"
     CDS             60665..61729
                     /locus_tag="KRH23_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HHS5224730.1"
                     /translation="MKRVDERNTMFARANYKKDSTAYNDYYKKNPDKKEIDDSIRNRP
                     NLCSEGTMTYNELNSPMASSAFDFLSDIKSLCEGKVSDTKVDVDAKSMTKKIKGLAKQ
                     YGASVVGITKLKDYHIYTNRGRHEENYGEEINLTHKYAIVFGCEMDKEMINRAPMICE
                     VIETSKCYVDASIVGMILSYYIRNLGYDARNHMDANYLVMPVFIARDAGLGDIGRNAI
                     LTNKDYGSRLRLGVVTTDIPLLEDEYVDFGLEDFCKVCKKCSFNCPSHSLSNDIKIGD
                     DGKYNWVIEHETCYIKWRYLGTDCGMCISACPFSQNLETIKNTTSFKGNNELIQKALD
                     EYTSKFGKRIFIPGNPSWLK"
     gene            61887..62573
                     /locus_tag="KRH23_001448"
     CDS             61887..62573
                     /locus_tag="KRH23_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HHS5224731.1"
                     /translation="MEKILVVEDDSILNKTLSYNLIEDGYIITSKFTAKSALKSIFEC
                     EFDLIILDINLPDKSGFELCNEIKENYNIPIIFLTANDMECDMIKGYELGALDYITKP
                     FNINIFKQKVKAFLNHLTIKTKQDYYRDGYLEINFSELSANINGNQIIFTPLEYRTLK
                     LLTENPKSILTRKVLLEKLWDIDANFVDEHTLTSVISRIRSKIEKDNLKYIKTVYGMG
                     YMWLGERNEF"
     gene            62563..63594
                     /locus_tag="KRH23_001449"
     CDS             62563..63594
                     /locus_tag="KRH23_001449"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HHS5224732.1"
                     /translation="MNFKKFSFSSIYLIIAVGIIFTVILFSISIYLITDDLKLIALLL
                     IYTIVLCGFIALIIFLLHKKIVIFCYKICHTLDSMMNSEDNIEIELEEETILSRINHR
                     LIRMYEVIQENRNSIAIEKADLQELVSDISHQIKTPIANLKMINTTLLNQTFKTEIQK
                     DFLMDMENQLDKLDFLMQSMVKTSRLETGIITLSKKKNSIYETIATALSGILFDAEKK
                     NIEVTVDCDPNLYIIHDKKWTSEAIFNILDNAVKYTNSNGKIRVATECWVMYTKIDII
                     DNGKGISESRQAEIFKRFYREEDVHDIEGIGIGLYLSRKIISLQGGYIKVTSDIGKGS
                     TFSIFLPNK"
     gene            63676..64341
                     /locus_tag="KRH23_001450"
     CDS             63676..64341
                     /locus_tag="KRH23_001450"
                     /EC_number="7.6.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHS5224733.1"
                     /translation="MSILQVINLKKYYGQSSNITKALDGVTLSIEKGEFISIVGTSGS
                     GKSTLLNMMGGLDNPTSGKVIIKGKELSTMTDEQLTIFRRRNIGFIFQNYNLVPLLNV
                     YENIILPIGLDGETIDKDFINEIINMLSLEEKLYDMPSNLSGGQQQRVAIARALVTKP
                     AIILADEPTGNLDSRTSSDVLSLLKVTSKKFNQTIVMITHNNEIAQLTDRIIRIEDGK
                     IVN"
     gene            64354..66771
                     /locus_tag="KRH23_001451"
     CDS             64354..66771
                     /locus_tag="KRH23_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHS5224734.1"
                     /translation="MFRNNNRTFIRKIALNDLKINKLKTYLSGIIIMISTCLLLTVTL
                     VSYNASVDLVNASPYHAIYKSVDEKAKNILYKNKNFSGVGTYKLIGSNKKTDCIMSIV
                     YADDTAIKLMNFQPLKGKLPTNKNEIAISEKYLQEFGLDKDIGDSIKLNYYDDITNKE
                     VQCDFIIVGFLENYYQDNAKQYYTVVSNDYFKNIASTPLQNKSNTFDESRPDTVDVLV
                     KLSEENTEKDSASIKTQLKKIGLSLGIKKYNIYLNDNYIESNLIDGEQIITVLVVGIV
                     VLFSSVFVIYSIFYISVVNSVQMYAKLKSLGMTSFQLKKIISLQGNILSIIFIPLGVI
                     ASCIIAYIIQPLAWQMIADLFIILILSLVMFLTVRISLFKPARIISKISAIEAMQYTE
                     TKFRKKVKNFSYINIKNLALKNIESNRKKNLIALISLSISGVLFISIANLANSIDFKK
                     QLSQQFVYNEDYIISIKSDNLYEHITEIQQNNPLTDSLKNEIKSIHGVKKLIESKSIK
                     SNIIEPYIKDRDEKQFITLIKGITPELSKSLEEYIVSGKIDYTHLDSDSLIINKYRTK
                     SYGLNLKVGDTVTFNIFSGNDIIKKKMKIIGIIDNSNTGGMFFASNKTLESLTPYNTN
                     LDFSILIDKKHSKEVEEKLLSIIQKNSNLMLYSYEDDYRMITRAFQYIIIASYIFVGL
                     ISCFGILNMTNTLINSVLIRKKEFALLQAVGMTRKQLRNMLYREGLNISIKAICTSSI
                     LGYFGSNLLCTFIKNVIRLDFINFKFSIFTILIFSFVLIGIQVLVTELLVRNIEKKSL
                     TERLRSQ"
     gene            complement(66952..67743)
                     /locus_tag="KRH23_001452"
     CDS             complement(66952..67743)
                     /locus_tag="KRH23_001452"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HHS5224735.1"
                     /translation="METKQYLIDFYNTYDEDSRLALKHGMVEFLTTMHYIDKYIKSGD
                     CVLEIGAATGRYSHTLARQGYDVDAVELVEHNIEVFHKNTQSNENISITQGNAMDLSV
                     FPDNKYDITLLLGPLYHLYNKEDKQQALHEAIRVTKPGGVVFAAYVISDGCLIDEGFH
                     RGNINVSEYIEKGLIDPQTFAAKSEPKDLFELVRKENIDDLMSAFNVTRLHYVASDGL
                     ALYMREAVDSMDDDAFALYLKYHLATCEREDLVGVTSHAIDIFRK"
     gene            complement(67776..68363)
                     /locus_tag="KRH23_001453"
     CDS             complement(67776..68363)
                     /locus_tag="KRH23_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HHS5224736.1"
                     /translation="MPPKVKITKEMILNTVLDITREVGFEAVNARSIASKLQCSTRPI
                     FTCYENMNELKNEFLAFAYEYYNQYVVNYRNSKSVSPYLLLPLSYIEFAQEETYLFKL
                     LFINDLDLMMKEANDFYKEIDNEKKARLFSESIGIDLECAKVIFLDLFLYTHGIAVLT
                     ATKKLTLDRYSAEKMLKNILTAFIRQEKSDWNLSI"
     gene            complement(68540..69931)
                     /locus_tag="KRH23_001454"
     CDS             complement(68540..69931)
                     /locus_tag="KRH23_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="benzoate/H(+) symporter BenE family transporter"
                     /protein_id="HHS5224737.1"
                     /translation="MERLARREQPHIKFGMFKIRIPFIHYRFEKPEAIQGIISSMTSL
                     GTIGLSTQILGLPYEVAWSMAIINSILYCLHVFMGDPVVPGWITASITLTTAYLLKFS
                     MGIERIQALTALQIDLGIIFILMGITGVAGKLVSKIPNSIKGGILMGVGISTIISEFN
                     PKGRFDSYPISITVGILVACFVMFSERFDTLKVKNKFLFHLGEYGVVSAILVSLIVGI
                     FSKEIEIPRFSFDNLVYIVDFKNLINTVSPFGIGFPSVMLFIQGIPMAFMIYIIAFGD
                     FITGENLVLSESENRKDEYIDFNSNRSNVISGIRNIFMAIFSPYIPMCGPLAATLTGS
                     VAQRYKVGKEAMQSVFSGMGTLVWVSAIFICFYPIAQIATPLIPLALSVTLLVQGYLC
                     TKLSMELCNTGVEKGLIGLMGGVIAAKGGTWGLAVGFILYFILIDSKKRKEKDINSIE
                     DCVYEILDKKKSI"
     gene            complement(70115..71419)
                     /locus_tag="KRH23_001455"
     CDS             complement(70115..71419)
                     /locus_tag="KRH23_001455"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase/bile acid-CoA:amino acid
                     N-acyltransferase family protein"
                     /protein_id="HHS5224738.1"
                     /translation="MKVNVYNVESFVDERLKIMVSDLIPNTKLKISVKMEFPWCKGEE
                     FSSYGVFCSNEKGEVDLDLVEPIEGTYKADNCMGLIYSLEKSKTEGKNFAENISIDKP
                     IIMNMIFETSIERKEVELKRIFKSEDITTKYISDEFIGKLFYKQNSNNKTILMLGGSD
                     GNLDALDLLAAPLASRGFNVLTVAYFALEGLPDKLEEVPLEYFEKVFEWISENEITST
                     KEIFVHGTSKGGELAFLLASRYEQIKKVVVSQPHIYCFQALNGLMSGNDTSSWSYKGE
                     PFPYIKVDNDIFFEEQKKNISKGIPFGFNSTYKKSLKRAENRKEARIKIENSKADILM
                     IAGKEDNIWNSYEACLKALEIFEENNYPYNVELLTYNNMGHPLPIPYIMPLKETLCMS
                     MSGGIFSSGGTVEGNSKGQFESWNRTIEFYKKPLSSDLNNYY"
     gene            complement(71778..72653)
                     /locus_tag="KRH23_001456"
     CDS             complement(71778..72653)
                     /locus_tag="KRH23_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase"
                     /protein_id="HHS5224739.1"
                     /translation="MITFDVNGAIIRFDDTKNNYNKIRKIFKLYALEISKNFERDCLN
                     SFQNLKQISDRGLSLGEKYIEESFKKGIETIVSFGIITIDIDTFKSVYCEKYLDFKRL
                     FNNLNKTFIIPNKNKKNGHASFLEIESTIKKMSNYLYNDCFKIHYAVVDALIENRITA
                     VHSYIDEESIKKSNALFNNYKDGFIGKADECKVVKQIITLNPYREDVYEFLVKEDGDF
                     SKEIERLTEFLGYDIREYKASLMDIYINELMESDENDVENAKEKIEKYARYIGCSDEN
                     LYVARVNAIYTFANA"
     gene            complement(72846..73532)
                     /locus_tag="KRH23_001457"
     CDS             complement(72846..73532)
                     /locus_tag="KRH23_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HHS5224740.1"
                     /translation="MFGVIANSLAIAGGCIVGLIIKGGLPQRVSDTIMNGIALCVLYI
                     GISGALEGKNTLVTIISVAVGALIGELIDIDKWVNKLGAFLQSKFSKGNKKDSIAEGF
                     ISSSLLFCIGAMAVVGSLESGLTGSHDTLFVKSVIDGIASIIFTASLGIGVMFSAISV
                     FLYEGIICVGASFLNGFLSDPVVTEMTAAGSLLIIGLGLNVLKLTNIKVANLLPAIFI
                     PILFGVFGII"
     gene            complement(73581..74114)
                     /locus_tag="KRH23_001458"
     CDS             complement(73581..74114)
                     /locus_tag="KRH23_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HHS5224741.1"
                     /translation="MSDLNNKKEQDENESSMNETKIYDILDKLNVEYDVVEHEAVYTA
                     EQLVILDGITKGCQCKNLFLRNAKGNKYYLIVVKGEKQVDLNSLKDKIGSSRLSFASP
                     ERLYNVLKLLPGSVNPFSLINDTERKVELYIDKDVIKEDYLNFHPNINTKTVNISRKG
                     FEEFLEYLKYPIQSIDV"
     gene            complement(74158..>74492)
                     /locus_tag="KRH23_001459"
     CDS             complement(74158..>74492)
                     /locus_tag="KRH23_001459"
                     /EC_number="3.5.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016812 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds, in cyclic amides
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="cyclase family protein"
                     /protein_id="HHS5224742.1"
                     /translation="KNSDFIIFKSGWSKFWDKKQYYVGYPTLTKEAANYIANTNIKGI
                     GIDMLSVDRYDTSVFEVHHILFEKGKIIIENLTNLENVPEKFLFIAAPFKYNDADGAP
                     VRAIAIVE"
BASE COUNT        27427 a        10411 c        10095 g        26559 t
ORIGIN      
        1 taaatcatat tcatttatat tattaaaaaa tttgtttata gaaactttta ttattttata
       61 taaaagtgat aaaaacttat attttgtatt tagtagagtg ttgctaagtg aatatattta
      121 aaatggagga aactttatga aacaaaataa atatgatgat gatagatttt ttaataaata
      181 cagtaaaatg gaacgttcta caaatggatt agcaggtgct ggagaatggc atgttttaaa
      241 aaaaatgtta cctgatttca aaggaaaaag agttttagat ttaggatgtg gatttggatg
      301 gcattgtcaa tatgcagttg agaatggagc aatttctgct gttggagttg atatttcaga
      361 aaaaatgtta aaagaagcta gaaacaaaac gcaacttgat aatataaatt acatatgtat
      421 gcctattgaa gatattaatt ttccaaaaga tagttttgat gtagttatta gttccttggc
      481 atttcattat attcaatcat ttgaagatat atgtaagaat ataagtaatt gtctttcaaa
      541 taaaggtaat tttgcatttt ctgttgaaca tcctatattt actgcatatg gaagtcaaga
      601 gtggtactgt gataaagatg gaaataatct acactggcca gtagatagat attttgaaga
      661 aggagtacgt aagtcaaatt ttctaggaga agaggttata aaatatcata aaacattaac
      721 aacttattta aatacgttaa tgaaaacagg atttgaaata ttagaaatta ttgaacctca
      781 accagaagaa aaactgttag atacaattcc tgatatgaaa gatgagctac gtagacctat
      841 gatgttactt gtatctgcaa aaaaaagata agtaaatata aataatcatt attgtagaaa
      901 aaaagttgta gaaaataatt acactaatgg agatgattat accagtggta ttaattacac
      961 cagtattaag gaggcaaaag cattcgttgc ttttgccatt ttttaagttg caattatact
     1021 tctacgtagt atatttcgtt tccattttct tctataagct ttttcatatc ttcaaatttt
     1081 aaaaatacag tagcagtatt atcatttgga tgtataccta ttttatccat ttttaataaa
     1141 tccttatcaa atacaacttt tacaacagcc tctttatcat ttaatatacc aaaaggagtc
     1201 acagctcctt tagtaagttt caagtatttt tgaagtcttt cttctgatgc aaaactaaga
     1261 ggtttactat caatttgttg acgaatatct tttaaatctg cttttttgtc tttacctaat
     1321 acaactaaaa aatgttcttt tcctttagca tcacgaagaa ataggttttt tacaacaaat
     1381 tccatatgta atgtttttaa ttcttccatt tcttcaattg tataaactgg tggatgattt
     1441 acagcctcat aaggtatgct taactcatct aattttttat atacttcctg ttgttgattg
     1501 ttcatgattt cctcccatta gaaatttatt ttatatataa ataatattat cacagaaaac
     1561 tttaaaagaa aacgttttat ataatataga caatagatta tatttttata aagaagcaag
     1621 aatactcaat aaaacttaaa gaaattaaac aatttctaaa aataccttga aaatagaacc
     1681 ttatttgcca tttataaatt atataaaaag ggattatata aagtcatata tgaaaaaact
     1741 atattatact atcttttctt tttggaataa actatacttt aaatatagat atttaattta
     1801 aataaatttt acagtattaa tagtaaatta tcttagaaag gaatgtgctt tatatgtcta
     1861 cagacaaagt tgttggaatc atagatgaag aaacggcaga acttgcagga attgaatata
     1921 ctggtaaaat ttatgcttct tctggtgtta taaaacatat aaagaaaaaa catagatgtc
     1981 aactgagtaa ggatattttt aatgatataa tagacactat aaaaatggta ttaaagtcac
     2041 ctgaatatat aggaagtcat cctaaaaaac ctggaaaaag tgtggagttt ataaaaaaaa
     2101 ttgatgatta tattttagta gctacagaat tagatacaaa aaaaggatat ttatatgtat
     2161 cttcaatgta tgctataaaa gaagcaaaat tagaaagtag agtaaacagt ggaagggtaa
     2221 aacaatatga tggttaacat aatattatta atttccccta aaatattgaa aaatattatt
     2281 atataagtta taatattaat atacacgtag atatttatta gttagatttg aggttggaaa
     2341 aggcacccaa tacgctacta tagagtagtt aatagagatg caggatacgc cgccctgcca
     2401 aatctaatta aattaaaaag agaggattaa ttcctctctt attgtttttt tgagatacta
     2461 atttaatcta taatagaaag attgaaggtc gttatacaaa aaaattttca gttatataca
     2521 ttaaactaat taaataagat atttataatc tatatgtgat acatattata tattaataaa
     2581 agaaaaatat atagaaaatc cttataaaaa tttaaattgt aatgaatagg aagtaattaa
     2641 aaagaatttt tattgatttt taaaaattta gttagaaact atatcattat ggtaaaaaat
     2701 gtattataat gtttagaaat attataataa ggagcgatta aacatgaatc tatcgaagaa
     2761 aatagaagat aaaagaaaag ctaaacagag agctgaaaaa gttaagaaag ctaaaattgc
     2821 tacagctggt gtggtattag gagctgttac tggtgcagtg agtggagtac ttttggctcc
     2881 taaatctgga aaagaaacaa gagaggatat aaaagatgct tcacaacaaa ttgctgaaaa
     2941 gataaatatg aaaactgtag atgtaaaagg caaagtatct gagaagctag aggataaaaa
     3001 aggaaacttt atagaatcaa agaaaaaaat aaaaaaatat atagataaca aaaagagtgt
     3061 tgaaaattct agtgaggaag ataaaataat agatatagtt gaaccagtta gtgttactga
     3121 ggaataatat ggacaataca ataacgatta acataagtat aatatatgta ttattagcta
     3181 tacttgcttg tattgcttta gtttatttaa ttattgtact tgttaaacta cataagattt
     3241 taaataatgt tggaactatg ttaaatgaaa atactcaaaa tataaataca actttaaata
     3301 atcttcctaa tgttgtagaa acttttggag aagtaggaga aaatatgaaa gatgtaacag
     3361 aagtagttac tgaagttaca gcagattttc ttgttactaa agacagtgtc aaatcaaata
     3421 tggatgttat agttgatata ttgactataa ttaaaaacat ttttctagat aaaaaataat
     3481 aagttaatat aaaataagcc tataagatat aatttaaacg accttaaaat agcatttata
     3541 aggtcgtttt ttattagctt gatttgacac tatgtgtttt taataattgg taatattcct
     3601 ctttatcatt tgaacatata tatctatgct tgttgtttca attacatcca taagaacatc
     3661 tttacattca agctcaaaat cttccattcc ttctaaatat tcatcatctt catcaaaaaa
     3721 gatataagaa ttatatagcc attcttcaaa tttttcttca agtatatccc aatacgaact
     3781 ccaaaataat ccacaacctg atatataaga tgctctactt tgatttatat aaacctcatt
     3841 tagaagcttt tgtaatctac tgctataaag aaaatctgct cttccactgc ttgatattaa
     3901 ttcatttaaa tcttctattg acattaattc aactttacca cttttatcat aaggagtata
     3961 attttcatca acccatttat gtggtttgtt ttctctgcat actgttgcta tcaactctac
     4021 aacttttgtt cttatcattt ttttatccta acttatttat tttttataaa ataatcatga
     4081 ttttataatt tatctatttc ttgtaatgct aatttaacag tttcatatct atcagcacca
     4141 tttattacta catcaccttt tacaagttta ttagcttctc cacctacaac ataaaccttt
     4201 ttacctaaac cttgcttata actagacgcc tcaattatta aagaatcttt caattgccaa
     4261 tgtaaaatct gagcagccac tttatcagca tcacctgtat aaacgattac attttcatac
     4321 actttatttt cccctccccc ttgagaattt gatatagatt tgtttagtat accttctgct
     4381 atcaatttag caactttatc tttattatta acataataat ctgtatctgc tttactatct
     4441 acaaaacata cttctattaa tattgctggt gcaatagtat gattaagcca ataaagacct
     4501 ctaacatcag actttgcacc cctatctttg aatactgtag ctaacctagt attcactctt
     4561 tctgcatagg ttttgccatt attagtctta tatattgttt ctgtccctac tggagttgaa
     4621 gttgtagcat ttgaattaaa atgaatctga acagccaaat cagtttcctg tttatttgct
     4681 atagcacatt ggtctgctaa atgagtactt gattcatcaa ctcttcctgt ataaacagta
     4741 gctccaccta ttttaagcca tttaacaatt aagtcattca gtattcttgt ttctttgctt
     4801 tcgtttatat acccaacagc tcctgtacct tttccaatta aagtgtgccc tggtattatt
     4861 actactttca aactaacatc tcctttacaa ttaaatttaa cttctattta atatatgcat
     4921 aacctagaat tttgtttctt tttatatctt atacttttat tataaaccat tttgtaaaaa
     4981 tatagaatat taagtaaata atgttaaaat tataattttg tatataagac attacttgat
     5041 tgcaataatt ttatagcata ttcatctatt ctatatccag ttctataata tatatgttta
     5101 attccagctt gaattatagc cttaatacaa tttaagcaag gaaagtgagt tacataaata
     5161 gagcaatctt taactgaaat accttctttt gcacaataat aaagggcatt ttgttcagcg
     5221 tgaatggttc taatacaatg tccatctctc atttcatgac caacttcact acaatgctta
     5281 tctccagaaa tactaccatt atatccagta gacactattc tgttttctga attaacaatt
     5341 atagctccta cataagctct atcacaagtt cctctttcag ctactgtttc gcacagtctc
     5401 ataaaatatt cttgccatga acatctattt tcaagttttt tattcaaatc atatacctcc
     5461 aaaatttata tctaatatat aagatttata ccttaaaaat aatattaaaa acaaatttat
     5521 acgataaata aaatttatta atactgtttt tagtctaaat tatttcattt taaattaaag
     5581 ttacaaggaa tctaaaatta tatatatctt tcttcgtaat atgaatgtta caatataaaa
     5641 aactgtctca ataaaataga gacagtttta cagtcaaagt ttataataca agttcatatt
     5701 tttctttaaa ttcttttaca gcttcgggcc atgccttttg ttctgtaata cctttttctt
     5761 tagctatttt aattgcaatc tctcttatca ttgcagcgcc ttctaatatt cccattttta
     5821 atctcccttc aaatatcttt ttgtatagaa tataaatagt gctaagattt attacatgct
     5881 gcatatacaa tatctataca acacataact tgtaaattcc ttttattttc atacgtcttt
     5941 aaccgacata taattatatt caataagttt taaaattatg aactcaatta taattatttt
     6001 tattttttta gaatctaaac actaaaaatt gtaggtaaat ttgtcttatg cctttataaa
     6061 tatttctaca gttttaatta ctggacatat ctatttttat tataaaaagc gcttaaaaat
     6121 cgagaatatc cgcataaaaa ctgtatataa gcaaaacgat taaagtaaaa agaagaaatt
     6181 tacttgaatg ttaaaatgcg ttgcttgaag caatgggcag ttttgcttat aatatcggta
     6241 acaactgaaa gaaaggtggt tagccctaat gttaagcgaa aacattaaaa caatcaggaa
     6301 gtcaaaagga ctttcacaac aagaacttgc tatcaaactg aatgtagttc gacaaacaat
     6361 atctaaatgg gaacaaggac tgtcggttcc cgattctgat atgttgattt ccatatcaga
     6421 ggtgcttgaa acgtccgtaa gcactttact tggagaaact attgttgagt cggaagttga
     6481 taacttaaaa gtgatttctg aaaaattaga gattataaac ttgcaacttg cacaaagaaa
     6541 aaacatgaga agaaaaatgt ttcattggtt atttatttta ttatgtgcag tcatagtaat
     6601 agtttttgtg gtcttagggg gactaaatag tccttacttg gattggaatt ataccgaccc
     6661 tgaaaccgct gtttttggag tagcttttca tgcttttgag tggctatttg tcagattagt
     6721 accgattgtc cttataggag caattattgg aatctttttg acacgtaaga aaatatgaag
     6781 taactctgct ttttataata cagcaagcgt tccttaaaag tgtcattcta catggcaatc
     6841 gaggacaact atgtaaggaa gaaccttttt gatttccaac taagcgaagt tattgaggac
     6901 gacagtaggc tcaaaaccgc attaagtaaa gtacaggaag caagactgct ggacttatac
     6961 tctcatgcgt cagatgcagg aaatgcgagg tctggtagca tgatttacaa cgatttgtac
     7021 aacgactacg agtagaaata tatggagata agtattattt acgaaatcag aaaagaaatg
     7081 acttgataat ttactcatgt tataattatt gatgtgaaat taataaatcg aaattccttt
     7141 tttggattta acaatactga gtaaggaaaa agtgaatgac ttttgcaagg aggtgttaat
     7201 atcagacaag taaagtcttt tgtttttcca gttatatcct taatattctt agaccaaatt
     7261 agcaaagttc ttataggatt attcttaatg gactttgaaa ttgatataat tgggaaattt
     7321 ttaagattca atcctgttca aaatacaaat ctctcttatg ggggaaactt tattggtatt
     7381 ctatctaatt tatgggtatt ggtattgttt aaccttttag ttatattagt tattatatct
     7441 ggatatgctt tttataaatc aaaaaatgaa caaacaagct attcagtaaa agtaattatg
     7501 tcttgtggac ttgctggtac aatatgtagc ttgatagata aattattttg gggaggaagt
     7561 ttagattttt tgcagatacc aagcttttta attttcgact taaaagactg ctaccttact
     7621 gttgcagaaa taatatttgt tgtcatagga attttgcata atagagaaat atcaatgaaa
     7681 gaatacatat atttttgcta tcctcagttt aaaagataaa tttagaagat aaatttaagt
     7741 ttcaaggtaa acttatttaa tcacagcaaa tagttggctt acttaagctt ttgggctaaa
     7801 ctgtgagcac taattaagtc tctgctatct aacaaacgga gcacaaaaat aaatattaaa
     7861 tattaaatat aaagcacagt taattttgat taaaaagttg actgtctttt cttttgtaga
     7921 aatttaagca taggtaataa agaaatgact gcatttaagc attatgtata taattggagg
     7981 caataaaaag ccagcaaagc ccataaaata gagctgtgct agcaacatga tgagttataa
     8041 gaagataatc aaaaacttac gctttatttt aatttaaaaa aatgattact gtaaagaaat
     8101 cattttttat tataatcact gatacatcaa atattctaaa taaaattttt atttatctgg
     8161 aattgtatat tttttctata atattaacta cagcgtacat tgcccaagca cagatagcca
     8221 atacaaatac tcccatcatt actaaatcta atttaaatac ttgagaacca tatactatca
     8281 agtagcctat tccatatctt gaaactaaaa attctccaac tattacacct acccatgcca
     8341 taccaatatt aattttagtt aaatttatta aatttcctgt gtttgcaggt aatatgagtt
     8401 taaataatat ttgagattta gtagctccaa agctttttaa catcttaatt ttttcttcat
     8461 ctatattcat aaaataatta taagctgaaa gtatagtaac aacaacagaa atcgttacag
     8521 ctgttacgac gattccttct attccagcac ctacccaaac tataattata ggagctaaag
     8581 cagtcttagg aagagcattt aaaactacca aaaatgggtc taatattttt gataattttt
     8641 ctgaccacca aagagcaatt gctaccaaaa tacctaatac agtacctata acaagaccaa
     8701 gaacagtttc atatacagat attccaatat gtttaaataa ttgaccacta aatgcatatt
     8761 gaataaataa attgtaaata tcacttggtt tgctaaatag aaatgtattt ataacattta
     8821 agtcagctaa aagttcccag attacaataa aaccaattaa aattaatagc tggtagaata
     8881 atacatttct tttttctctt tttacacctt taacatagtt tatatatcct tcagatcttt
     8941 tattaagcct catgtgtatc tagctccttc cataatatgt cgaaatactt ttgaaaatca
     9001 ggaactttac gtgttttgag aggcgttttt gttccatcca tgttaagttc aatatcgtaa
     9061 atatttttta tggtagctgg tcttttagat agtattgcaa ccttatctga tatgcttatt
     9121 gcttctgcta tagctaaaaa agtgcaacta attgcttaaa gaaacagaat tatccacttc
     9181 agcacccata taaacaatat taagatttcc taaactgcta tcccaaacga tactattaat
     9241 aatagtagat aataacaatc tcttatcatc taaactggca ttatcaactt catcattaaa
     9301 tctcttcaaa ttactaacaa taatatcaat attaatactg tcactactaa tattgatgtt
     9361 actagattcc aaagtattaa tcttatcctt taaaatacta atctcattat ttaggctctc
     9421 aatctgggaa actatataat cagaagcagt actaccagta ttttttgcaa gctctataac
     9481 taaattttta ataagttttt ccttatctaa aatttgattt ttaagtaaat tagtctcaga
     9541 tttaaaaata ttaaaaacat tatcagtctt aatgttatta ttattgaatg cacttataat
     9601 agactcttct ttacaattct taattttatc tataactaaa ctttcaacta atggaccatt
     9661 aagattttta cagttgcaac tatcagaccc aagtgttttt ttagtaccac aaatataata
     9721 atactttaaa tccttgtcag tttttttgcc tttataggta attctcatat tagaaccaca
     9781 tttaccacat tttataagac cagataaaag agcagttttt ccagttgata tccttggagt
     9841 tttatcacga tttttatcta attgattttg tacttcaagc catatttcag gttctatgac
     9901 tccatggtgt tttgcaattg ctgctattga gttagatgta tttttagcat aggtaaggat
     9961 tccacatttt ctatctggag tacctacaac atccatacca ctatttttaa ggtaatctaa
    10021 aatttcatca ttagctttta catatgctgg atttctaagt attctagata aagaactagg
    10081 gtcaaattta ccaccacgag gaccccttat tccattatta tagacatatt tatataactt
    10141 agataaggac ctaagttcta aatatttatt gtatattagc tttacaatct ccatttgttc
    10201 atcatttact tgaagcttat acatacttct ttcttttaga ttttcatcta agaatgtgat
    10261 tttttcactg ttgaatccat gaggtgtatt gcctccaagc catctaccac tacgggctaa
    10321 ttcatacata ttgtctttta tacgttctgc tattgtttct ctttctaatt gagcaaatac
    10381 acttgatata aacatcatag ctcttcccat tggagttgaa gtatcaaatt gttctttgat
    10441 agatataaat gatatgctta gttcatttaa tttttctatt aaagtagaga agtcagatac
    10501 atttctcgat atcctatcta atctataaca aactaggtaa ctaaatttct tatctttggc
    10561 atcctgcatc attttcttaa attgtggtct atctatattg ctaccactaa atccctcatc
    10621 ttcatatatc aaaaaatctt ttacaccaat agactttgca taatcaatac ataattgtat
    10681 ttgattttct atagaatcac cttttccagt aaatcttgat tttcttgaat aaattgcagc
    10741 tttcaaaatt aaaacctcct ataagttagg atatatattt gaaactattt atctacaacc
    10801 ttttaagtaa acttattaga atgaatttat taattaggta aatttatata attctacttt
    10861 ttataatata tgactattta ttttatttct ttactattca agttctaaat caataataaa
    10921 ttttgatatt taattgtatc aggacaaatc tctaatttca tagattatta atataaaatc
    10981 ataggttagt gtgaaaaagt tgaaatttaa atattttaaa agataatttt tttgaactaa
    11041 taggtataac aaaaatttat agggggattg catatggaaa tcaatgttat agaaattttc
    11101 cctaaagata aagctaaact taataaaata gaaatggata aagctagttg gtttgtaaat
    11161 ataataagta aaaaatatcc taaagaagct ttaaatgaag catttagtac tttagaaaaa
    11221 gaattaaata taagtaaagc taatacataa gctttgatta ttgattttat atactattgg
    11281 ttttatacac tatgacttga cattatatta atcaaatagt atatttttaa atatagcaca
    11341 atgaagtgtt aaaagagcaa tggagctcca tagataaagt ctatggagct tttttgcgta
    11401 tttaacttaa ggaggatagg actttgaata actttgagat taaaactaga ataaaatttg
    11461 gagaaggttc actaaaagct ttgcaagaat taaaaaacaa aaatgtatta ataataacag
    11521 acccttttat ggtgaaatca aaaacaatag ataaaataac atctaattta ataaactcaa
    11581 catatcaagt ttttgaagaa atagtaccag acccaccaat agaagtagta gtagcaggaa
    11641 tagaatcatt taaatctata aatccagacg taataatagc attaggtggc ggttctgcaa
    11701 tagatgcagc aaaatctata atggactttt ctaaaaaaat attaaaaatt aacgaagtag
    11761 agtttatagc aataccaaca acaagtggaa caggttcaga agtaacatca tttgctgtaa
    11821 taacagatag tcaaaaaaaa tgtaagtatc cattagtgag tgatgattta cttccagata
    11881 tggcaatact agacccagaa cttgtaaaaa ctgtaccaaa ttttataaca gcagatacag
    11941 ggatggatgt attgacacat gctatagaag cttacgtatc tacaaattct aatgactttt
    12001 cagatgcact agctgaaaaa gctataaagt tagtatttaa atacttaata aaagcatata
    12061 aagatggaaa tgacatagaa gctcgagaaa aaatgcacaa tgcatcttgt ttagcaggta
    12121 tggcatttaa ccaagcatca cttggcataa atcattctat tgcacatgta ttaggtggaa
    12181 aattccatat accacatgga agaacaaact ctatattact tcctcatgta atagaatata
    12241 attcatcaat agtaggatat actaacacaa cttactctgc tacagctaaa aaatatgcac
    12301 aaatagcaga attagtagga cttgggagtg ctaatataag aatatctgtt agaaatttag
    12361 taaatgaaat aaagaaacta caaaaagaaa tgaatatgcc aactaaattg acacaatgca
    12421 aattaagttt agaagatata actaatgaag aaagagaaat agcaaaactt gctataaaag
    12481 atacttgtac attaactaat cctaaggtac caactgaaga tgatataata aacatattaa
    12541 agaacattaa ataactacat tttattacat gtaaatataa tattatacaa atagggaaaa
    12601 tgtttttaaa aatataaatt atatattgac aaatataaaa cataaaacta taatgaaagt
    12661 atcacaaagg cgtgatactt tagtagaaag caatggagct tcttaggaat attaatatta
    12721 ttcttatgga gctcctttta ttttaatcaa atagcttttt aataaactat attcaaagaa
    12781 agcagggaat aaatttgact gaagaatcta agcaaagagt tattcaagaa tatgttcctg
    12841 gaaaacaggt tacattagca catatcatag ctaaccctaa tgaagacata tataagaagt
    12901 taggattagt acttgataaa aaagatgcaa taggaatact tacaataaca ccaagtgaag
    12961 cgtcaataat agcagcagat gttgctacaa aggcttcaaa tgtatcttta ggttttatag
    13021 atagatttag tggttcagta gtaatatcag gtgatgtaag ttctgtagaa tcagcgttaa
    13081 atgatgtttt agaagtctta ggaaatatgt taaacttctc atctgcaaaa atcacaagga
    13141 cataataata caatgaagaa tataatattt atgggaaaga caggtagtgg taaaactacc
    13201 ttatgtcaaa aactagacca gttagaatta aagtataaaa aaactcaatc agtggaactt
    13261 tataataatg caatagacac tcctggtgag tatatggaaa atagaaacct atataatgcc
    13321 ttaataacaa catcagcaga tgctaaaatt atagcaatag tgtatgatgc cacacaagaa
    13381 gaaaattata tagcaccagg ttttgccagt atgttttgca aagacgtaat aggaattata
    13441 actaaaataa ataaagctac tgaaaacgaa gtcaatatag cttatgaaag actatcacta
    13501 gcaggagcaa gtcaaatctt taaaatagac acagttgata atattggact tgaaaaatta
    13561 tttaaatatc tagaaaaata taaaaatata gattaagttt aaggggaaat atttttttat
    13621 tcaaaaatat tattaaagta tgataaaata aaaaaatgta taaactattt taagaagatt
    13681 taatctttaa gcgaggtagg aacatgggga aaaaaatact attggttgat gatgaaccac
    13741 tgttaaggat ggatacaaaa gatatattag aaagtcatgg ctatgaaata ataggcgaag
    13801 caagtgatgg atttgaagct gttgaaatgt gtaaaaaaca caaacctgat ttagttataa
    13861 tggatataga gatgccaata cttgatggta taaaggcagg caaaataata tgtaaagaaa
    13921 atctagctgg tggagtactt ttattaactt catttgaaga taaagaatac gtagaaaagg
    13981 ctaaaagtat aggtgcttat ggatatttag taaaaacagc aagtgaaaaa tcacttatcc
    14041 caaccataga aatgtgttta aataaggtaa atgaatttga aaaaatgaaa aaagatttag
    14101 aaaaagtaaa ttctaaattg aatgaaagaa aattagtaga aagagcaaaa ggtatactta
    14161 taagagagtt taagatttct gaggatgaag catacactag aataagaaaa ttaagtatgg
    14221 ataaaagaac tacaatgatg gaaattgcca aaatgattat aataggatac gatgactaat
    14281 acgataaaaa aaatatcaac tgcacaaaca tacttaaata ataacgagat tgaaaaaatt
    14341 atagaagtat caaaatcctt agatttaatg gcttcttttt atgaagctga tgtttttata
    14401 gatgtactaa gtaaatttga tgatgaagca attgttgtgg cacatggtag acctaaagaa
    14461 aagtcaatgt actgtgaaaa tgttataggt aaaaaggctt taattgaaaa tgaaccagga
    14521 gttataaagt gcttaaaaac aggagaaaga gtaagagata ttaaagcttt aacacaggaa
    14581 tataaactgg tcaaacaaaa tattcagcca ataacactag atgacaaagt tttagcagta
    14641 ctaatagttg aaaaagatat aagtagtgaa gttaagaatg agtttaatgc tagtgaagac
    14701 gaagaaaata aaaatttaca tcagtttata aaacttatcg gaaataatga ctttttagtt
    14761 gataatttaa attcagccat attaatattt gataaaaatg gaaaattaaa aattaaaaat
    14821 cgtattgcaa ctgagatata caaaaatctt gggtttggat atgatataca agatatgcat
    14881 tacaatgatt tagatataga aaccaacacc tttgaaaata tattaatgga tgaaaattat
    14941 gatgagacaa atgaagtttc aataggtaat atgtttttta aaataaagac catatacatc
    15001 aaagatgatg aatttaaggt ttgcaaaata gtacaagata taagtgattt aaagagaaaa
    15061 gaagaagaat tagttttgaa aacagtggct ataagagaag ctcatcatag agtaaaaaat
    15121 aatcttcata cagtaatatc tataataaaa aaacaaagta gattatctca aaatgatgaa
    15181 gtaaagcagt gtttagataa cataataaat agggtatttg caatactttc gactcattat
    15241 ttactatcta aagaagttga taataatata tctatacgag aaggtatcaa tttattagtg
    15301 tcaaatattc aaggtggcta tttatttagt aaggatatag atatacgtat aactggtgaa
    15361 gattttaaaa ttagtggaga aaaagcaaca gcaatacttt tggttataaa tgaaatacta
    15421 caaaattgtt atgaccatgc attttcggat agagaacatg gtactataca aatattaata
    15481 aataaagata acgactatag aaatattgct attatagatg atggaattgg atttgatagt
    15541 aataatataa ataaaaatag cttagggaca tatataatag atagttatat aacacagatg
    15601 ttaaaaggaa atatagagag aaaaagtagt gagaatggta cagaagtatt aattactata
    15661 cctacacaaa ttaatattta aataataact catctacaaa gtagtagttt taattgagca
    15721 aagaggctta aggttattaa tagattaagt taattgaatg tatttataaa aattataagt
    15781 atatattcaa tttaacaggt atttattata actttaagcc tctttgcttg tttaagacat
    15841 acttaaattt taggaggtga gaaaatgaga gaagagttat taagtgttgg tattgacatt
    15901 ggaacaagta ctactcagtt aattttttct aaattaatag tagaaaatac tgaatcaaat
    15961 ttttcggtac ctagaataag tatagtagac aaagaaatta tttataaaag caaagtttat
    16021 ttcacccctc ttatttcaaa taatgaaata aatggtcaac aaataaaaga tatagttgaa
    16081 aatgaatata aaaaagcaaa tatatctaaa gaagatatac atacaggagc agtaataata
    16141 actggtgaaa cagctagaaa agaaaatgca aatgatgtac ttcatacttt gagtggattt
    16201 gctggggact tcgttgttgc aacagcagga cctgatttag aaagtataat atcaggaaaa
    16261 ggagctggag ctcatattta ttcaaaagaa cattcaacta caattgtaaa tatagacata
    16321 ggtgggggaa ctagtaacat agcctcattt aaaaggggag aagtaaccga tactgggtgt
    16381 ttggatatag gtggaaggct tgtaaagata gataaaataa gtaaaaaaat aacttatata
    16441 tcacctaaaa tagataaaat cataaaagat aataatttaa atcttcaagt aggtacaatg
    16501 gctactgtag aaaatacaaa gccaatagtg gatataatgg ttgacttatt aatggaaagc
    16561 ataggattaa agaaacagac acctttgttt gattttataa taaccaataa atcaataagt
    16621 atagatgaaa atattaaaaa tgtttcattc tctggtggag tagctgatta tatttactat
    16681 gatggagaaa taaaagatta ttttgaatat ggtgacttgg gaattttact tgggcaagca
    16741 ataaaaaatt gtgaatacct taaaaaagta aatgtagtta aatctatgga aacaataaga
    16801 gccacagtgg ttggagcagg ttctcatact actgaagtaa gtggaagtac aataacttac
    16861 actagcgaaa agtttccact taagaacttg ccagttttaa aattatcaat tgatgaagaa
    16921 acaggcactt caaaacaaat cagtgaagct ataaaaaata aacttaattg gtttaaacta
    16981 gaaaatgatt tacagaaagt tgctatagcc atgataggaa agaaaaatcc aaccttttta
    17041 gatatacaag agtatgctaa agggtttgta gatggaatgc aacaaatcat agaaaatgat
    17101 ttacctttta tagtaattgt tgaaaatgat atggcaaaag tgttaggtca agcaatatat
    17161 gcattattaa attatgaaaa agaaattgtt tgtatagaca gtgtcaaggt tgaaaatgga
    17221 gactatatcg acattggaaa acctatagtt gaaggtaaag ttttacctgt ggtaataaaa
    17281 acattagttt ttaattaata gaaggaggta agtaaatgat tttaaataca aaattatttg
    17341 gacgtactta tcagtttaaa ggcttatatg atgtaatggc taaagctaat gaagaaaaat
    17401 caggagataa attagcaggt cttgcagcag aatcagctga agaaagaata gcagcaaaag
    17461 ttgttttatc acacataaaa ttggaggata taagaaataa tcctgcagtg gcatatgaag
    17521 aagatgaagt aacaagaata atacaagatg ctgtaaatga aaaagtttat gaagaaataa
    17581 aaaattggac agtctctgaa cttagagaat ggctattgga ttcaaatact acaagtcttg
    17641 atataagaag aatatcaaga ggattaactt ctgaaatgat agcagcagtt gcaaaattaa
    17701 tgtcaaatat ggacttagtt tatgcagcta aaaagataaa ggttactgct cactgtaata
    17761 caactatagg agaacaagga acattatcag caagacttca acctaatcat ccaacagacg
    17821 acccagatgg aatacttgca tcacttcttg aaggtttaac ttttggtata ggagatgcag
    17881 tacttggatt aaatccagtt gatgactctg ttgagagtgt tactaaagta ttaaaaagat
    17941 ttgaagaagt aaaacaaaaa tatcaaatac caactcaaac atgtgtattg gcacacgtta
    18001 ctacacaaat ggaagcaata agaaatggtg ctcctgcaga tttaatattc caatctatag
    18061 caggttctga aaaaggaaat gaagcatttg gatttaatgg cgacactata gaagaagcta
    18121 gacagttagc tttaaaacac ggtacagcta caggacctaa cgttatgtat tttgaaactg
    18181 gacaaggttc agaattatct tcagaagcac atcatggaat agaccaagtt actatggaag
    18241 ctagatgtta tggatttgct aaaaagtatg aaccattctt agtaaataca gttgttgggt
    18301 ttataggacc tgagtactta tatgatgcta gagaagttgt aagagcagga cttgaagacc
    18361 actttatggg taaactacat ggcttaccaa tgggtgttga tgtttgttac actaaccata
    18421 tgaaggctga ccaaaatgat atggaaaact tagccatact attaacaaca gcaggatgta
    18481 cgtattttat gggaatacct catggagatg atgttatgct taactatcaa acaacaggat
    18541 accatgaaac agcatcactt agagaaatgt ttggactaac agcaataaaa gaatttgatg
    18601 cttggatgga aaaaatggga ttctctaaag atggtaagtt aacagagttg gcgggagacg
    18661 catctgtatt attaggatag gaggtattta atatgaatga gaaggattta aaagcattgg
    18721 tagaacaatt agttggacaa atggttggag aattagatac taatgttgtg tctgagactg
    18781 ttaaaaaggc aactgaagtt gtagtagaca acaatgcttg tatagatgat ataacagaag
    18841 ttgatataag aaagcaatta ctagtaaaaa atcctaagga tgcagaagct tatttagata
    18901 tgaaagcaaa aacacctgca agattaggta taggaagagc tggtactaga tataaaacag
    18961 aaacagtttt aagatttaga gcagaccatg ctgctgcaca agatgctgta ttctcttatg
    19021 tagatgaaga atttataaaa gaaaataata tgtttgcagt agaaacttta tgtaaagata
    19081 aagatgaata cttaacaaga ccagatttgg gaagaaaatt ttctccagaa actataaata
    19141 atataaaatc taaatttggt acaaatcaaa aggttttaat attagttgga gatgggctta
    19201 gctcagctgc aatagaggca aatttaaaag actgtgtgcc agctataaaa cagggtctaa
    19261 aaatgtatgg tatagattca agtgaaattt tatttgttaa acattgtaga gttggtgcta
    19321 tggaccactt aggtgaagaa ttaggttgtg aagttatatg tatgttggtt ggagaaagac
    19381 caggattagt tactgctgaa tcaatgtcag catatatagc ttataagcca tatataggaa
    19441 tggcagaagc aaaaagaaca gttatatcaa atattcacaa aggtggaaca actgcagttg
    19501 aagcaggtgc tcatatagct gaacttataa aaactatgtt agataaaaaa gcttcaggaa
    19561 tagaccttaa ataaagtcga gggagtgtag aatatgaaaa atgatgtaat tcgtcctaat
    19621 atactaggaa ttaaaataat ttcaaatata agtccagaaa tggcacaaaa actagaatta
    19681 aaatcacatc acaaaagctt aggtttaata actgcagact gtgatgatgt tacatataca
    19741 gctcttgacg aagcaactaa agcttcagaa gttgatgttg tatatgcaaa atcaatgtat
    19801 gcaggtgctg caaatgcttc aacaaaactt gctggtgaag tattaggaat aatagcaggt
    19861 ccaagcccag cagaagtaag aagtggtcta aatgcagtag ttgattttct agagtatgga
    19921 gcaactttta taagtgcaaa tgatgatgat tcaatagcat actatgctca ctgtgtatca
    19981 agaacaggta catacctttc agaggtagca ggaataagag aaggtgaagc attagcttat
    20041 ttagtagcac caccacttga agcaatgtat gcactagatg cagcaatgaa agctgcagat
    20101 gttaagatgt gtgaattatt tgcacctcca actgaaacaa actttggtgg agcattactt
    20161 acaggttctc aatcggcttg taaagcagca tgtgatgcat ttgcagaagc agtaaaatca
    20221 gttgcagaca atccaacagg attttaagga tagttagatg gatgctatag gcttaataga
    20281 agtaatagga tatgttgctg caatagaagc ttctgatgct tgtttgaaat ctgcaaatgt
    20341 taatattgta agagttgata aggttggggc aggtattgtt actttaacaa tatgtggaga
    20401 tgtcggtgct ataaaagctg ctttagaagc gggtgaaata gcagcttcca gagttggtac
    20461 attaagaaca tcacatatta taccgagaat ccataatgaa gtaacaaatg ctttattcaa
    20521 aactaaagaa cctaaagtct gtgaagtttc agaagataaa gaaaaaaact ttgagattac
    20581 attggaaata gctgataatg tatcgaaaaa tttatcagaa aaagaaaatg taattttaga
    20641 tgtcaatgaa aacagtggag atactgaaaa tttatatagt gatatagata aaacaaacaa
    20701 aaaaattgaa acagttgatg atagtttaac agaagctaat gaggaaaaaa tagaaaacac
    20761 taatgataaa gaagtattgg aacaagttaa aatagaaaat tccgattttg atagagatga
    20821 cctatcaaag aacagtgtaa aaaaacttaa agctatggct aagaaattag attcttcaat
    20881 aacttataaa gacttaaatg ttcttaaaaa agaagaatta ataaacttag ttaaaaagct
    20941 tagcagaagg gatagatagt tatgacactt ttagataaag atttagtatc tatacaagaa
    21001 gtaagaactc ttgtaagaag atctaaagtg gctcaagaga aactttctaa aatgagtcaa
    21061 gagcaaatag ataaaatagt aaaagctgtt gtagatgcag catttaataa tgctactaaa
    21121 ttagctaaaa tggcaaatga agaaactgga tttggaaaat gggaagataa agtaattaaa
    21181 aatacttttg catctatggg agtttatgaa actttaaaga acacaaaaac tattggaata
    21241 attggtgaag ataaagaagc caatacgata gatatagcta caccagttgg agttgttgca
    21301 ggtcttatac cttcaacaaa cccaacatca acagtaatat acaaaactat aatatctcta
    21361 aaagcaggaa atactatagt tttctctcca catccaaatg caaaaaactg catacttgaa
    21421 acagttaata taataagtga ggctgctata aaggctggag ctccagagga ttcaatatta
    21481 tgtataacta atccaagtat agttggaacc aatgaattga tgaaacataa agatacaaac
    21541 ttaatactag caactggagg agaagcaatg gttagagctg cttactcttc aggaacacca
    21601 gctattggag ttggaccagg aaatggacca gcatttatag ataaatcagc aaatgttaaa
    21661 ttagcaatca aaagaataat agattctaaa acttttgata atggtgttat atgtgcatca
    21721 gaacaatcta tagtaataga aaaatctatg gaagaaactg ttttaaaaga gcttaaaaat
    21781 caaggtgcat atgttttaaa tgaagaggaa agtgaaagat tagcaaaatt catattaaga
    21841 gctaatggta ctatgaatcc acaaatagtt ggtaaaagtg ttgaggtaat agcaaattta
    21901 gcagacttaa caaatgtacc taaaaataca aaagttctag ttgcaagaga aaataaagtt
    21961 ggtcacaatg tagcctattc aagagaaaaa cttacaccaa tactagcgtt ctatgttgaa
    22021 gaaaatgtag aagctattat gaacagatgc agagaaatat tgttaaatga aggtgcaggt
    22081 catacattct caatgcatgt aaatgatgaa gaattggtaa aaagatttgc ccttaatatg
    22141 ccagtatcaa gaatacttgt gaatactcct tcagcacttg gaggaatagg tgcatcaaca
    22201 aaccttgtac cagcactaac acttggttgt ggtgcaatag gtggaagttc aacttcaaac
    22261 aatataggac cacttgattt aataaatgtt aaaagagtag cttatggaat caaagaaata
    22321 gaagaacttg gaagagataa atctcaagtt gaaaaatcaa tgtttgactc aatggataaa
    22381 gaagaattaa taaatcttct tgttcaaaaa ctagtcaaag aactagcata actaaaataa
    22441 acaatgaaac ttatggctat cgctataaat ttctaaaaat ataaactata aaaaactata
    22501 aaattaaatt tttggaggat aagattatgg caagtgcaaa cgcattagga atgatagaaa
    22561 ctaaaggatt agtaggagca atagaagcag cagatgcaat ggttaaagct gcaaatgtac
    22621 aattagtagg aaaagaacaa gtaggtggag gattagttac tgtaatggta agaggagatg
    22681 ttggagctgt taaagctgct acagatgcag gagctgcagc tgccgagaga gttggagaac
    22741 taatatcagt tcatgttata ccaagaccac actttgaagt agatgctata ttaccaaagg
    22801 tatcagctga gtaatataag aataattata aaatttaaat tttgattgaa aaagaggcta
    22861 tctcaaaaat gagtcttact aataaactca atgtattttg aggtagtctt ttttatacat
    22921 ctaataggag atgtgataaa atgggtgttt taacagaaaa cgaagtaaaa agaaaaattg
    22981 gaaaaaacaa aaataatata actgaatttt atatagaaaa aggtcaaata ataactcctt
    23041 ctgcaaaatc ttatttagct gagagaagta ttgagcttaa atatgttgat aaactttcag
    23101 atgtaaacaa tgaacctaaa gaagttgtaa aagaagtagt taaagagaaa aaatataaat
    23161 atactactgt atttggcgcc aaattggatg aaaaaccaga acatatgact caattaaatg
    23221 gaaatctttt agtttttaaa gaccataaaa gaataatatt gagaggaaaa atagattctc
    23281 ttgaatcaga aatactaaag gtacagatac tttgtcagaa actagatatg ccaaagcttg
    23341 ttaaggaatt gcaagaagta ttagactttg taagaaatat aatgagatgt gaagttttag
    23401 atgaaaagct aggggacttt aaacttttag gattaactcc tcaagaactt agagaacaat
    23461 ctcactatcc taaaaaatac tttggtatag gacatgaatt tccaagttat gaaatgggag
    23521 aagtagtagt agctataaat agtataagaa gtaatacacg agaggttgaa cttgcagcct
    23581 atgaagcatt taagggtgag tatggaaatg ttcacagaga agatttaata aaggcactta
    23641 atagattatc gtcagtattt tggataatga tatataaggt tagaactaat aagtataagt
    23701 agttggagga cataatggag aatctattaa atgaaatagt ggaagaagta ataactagag
    23761 ttaaaaaaga agcatttata gaagttgaag catcaggaag acacgttcac ttaagtagag
    23821 aagatgtcga taaattattt ggagaaggat atactcttac aaaactaaaa gacctatctc
    23881 aaccaggtca atatgcatgt aaggaaagag ttacaataac tggtcctaaa ggaagtataa
    23941 aaaatgtagt tgtacttgga ccatgtagaa atgaaactca ggtagaaata tctttaacag
    24001 atggttcaac tcttggacta aaagctccta taaaacaaag tggagactta gaaggtactt
    24061 taagtattaa aatatcaaca caatatggtg aagttgaact tgataagggg ctaatggttg
    24121 ctaaaagaca tatacacatg actcctaaag atgctgaaaa attcaatgta tgtgataaag
    24181 agatagttga agctaaggtg atgggtcaaa gacctttaac atttgatgat gtagtaataa
    24241 gagtgagtga cagttttaaa acttatatgc atatagacta tgatgaagcc aatgcatgtg
    24301 gttattcaaa aggaactgtt gctaaaataa taaagaaagc ataaatttaa cctactatat
    24361 aaattacctc tagggaggat ttaatatgaa ttatgataac cttgtagatt taataacgga
    24421 agaaatctat aaaaaaataa atagtaatga aataaaaata tctaataaac ctaaagctgt
    24481 gattgtattt gaacaagata acaataaatt taacttatta aaagatgaat ttgaaatagt
    24541 agaatttgat aaaagtataa gggaatgtga aatagtgata gtttcaagac tttgtatgag
    24601 ggggctatcg aatatagcac ttggaaattc aacaagtgat gaagaaagat ttatactaaa
    24661 aatgattatg aagggcaaaa aagtatatgt cctagatgaa ggaattgaat acaaaaaata
    24721 taaggatact gcaccaaaag cattatataa gaaatttatg tcatttgaag atgaaatatg
    24781 taaatttggt gtagaaattg taaaagactt aaatgttata actaaaaata agttaaatat
    24841 aaagaaagaa ttagaaagta ctagaggttc taaaaaagaa gatacaaaag ttttagataa
    24901 agatgtttta aatttaacca gtgtagaaag tgtaaaaata gataatgaat ttagtttgga
    24961 tttaaggaat aaaaaactta tatcggaagc tgacttaaga aaaccaacta taaatggagt
    25021 taaaaacata ttagttaata aaaaaagtat aataacacca ttagctgtag attttatgag
    25081 aatacaccat ctcaaactaa agaaagtgta aggaggtaat tttatggata taggaaaagt
    25141 tgtaggtaat gtttgggcta caagaaaaga tgaaaaatta tgtggccaaa aacttttagt
    25201 tgtaaaaatt ttaaaaacta aagacacata caaggaaggc ttcatggttg cagccgataa
    25261 tgcaggagca ggaaatggag acttagttct tatatccaaa ggttcctcag ctagagagtc
    25321 gattgaaaaa tctcatgttc cggtagatgc aactatagtt ggagtagtcg attcgtttga
    25381 ggtgtttgat gaataaaagt ataggagcta tagagtttaa aagcattgct aaaggtatag
    25441 aagtatccaa tgaaatgata aagaaatctt cagttgatgt attgtactta aaaagtattt
    25501 gcccaggtaa atttctaata atagtaggtg gagaaacttc ttatataaat ggatgtgtag
    25561 attatggaat aaaacttgga gaaggatata ttgtagataa cttcgtaata aatgcaattt
    25621 cacaagaaat attagatgga tttaaaaata agtatcaaaa gctagatagt atagtctcta
    25681 taggcgttgt tgaaagtagt aaagtatgcg ctggaataaa aatgcttgat aagactttaa
    25741 aatctggcga cttagtatta gtaaaacttc aattatcttt tgctataggt ggcaaattag
    25801 tatatatagt agcaggagat ttaagtagtt tagaatattc attaaaagaa agtgaaaatg
    25861 tagtaagaga aaaagaagta atatataaga ctgtaatacc atcagtagac agtcaaataa
    25921 taaaaagtct aataaaataa tggggtgaat tatgagtata aacgaaatta taatctatgt
    25981 aatggtagtc ttcatggtac ttggagctat agataaatgt ataggtaaca aatttggtct
    26041 tggagaacaa tttgaagaag gtataatggc aatggggtca cttgcagttg caatggttgg
    26101 tgttatatgt ttagcaccag ttcttgctga tgtattaaga ccaattgtag taccagtatt
    26161 taatatactt ggagctgacc cagctatgtt tgctggaagt ttattagcta atgatatggg
    26221 tggtgcgcca cttgcacttg aacttgcgaa agaccctaat gctgggttat ttggtggatt
    26281 aatagtaggg gctatgatgg gacctacaat agtatttata ataccagttg cgcttggaat
    26341 aattgaaaaa gaagaccaaa aattcttagc aacaggaata cttgcaggta taataacaat
    26401 acctattgga gcattcgttg gtggattagt tgcaggattc gaggtaatga tggttcttag
    26461 aaacttagtg ccaataataa tatttgcagt agttatagca cttggattat taaaattcga
    26521 aaatgctatg ataaaaggat tcacatactt tggaaaaggt gtagtaatag ttataacttt
    26581 aggacttgct gctgccatag ttgaagcttt aacaggaata gttgtaatac ctggaatgaa
    26641 accaatcagt gaaggtatag aaatagttgg agatatagca atagttttag caggagcatt
    26701 cccattagtg tttgttataa caaaggtatt taataaacca ttaatggctt taggaaaagt
    26761 tcttggaatg aatgatgtat cagcagcagg ccttgttgca agtttagcta actgtatacc
    26821 aatgtttggt atgatgaaag atatggacaa tagaggaaaa ataataaatg tagcattctc
    26881 tgtatcagca gcattcgtat ttggagacca cttaggattt acggcaggat ttaattctaa
    26941 tatgataaca ccaatgatag ttgctaaatt agttggtggt ataacagcag tattgttagc
    27001 tatggttatc gcaaataaga cactaaagaa ggagaatgta taagatggat atatcaaata
    27061 tagataaaaa tttaattgaa acattagtaa gacaaataat agaagaaaaa ataagtggaa
    27121 ctaaagacac agtagatttt gttagaaata aagacattag tggaataact tctataaagt
    27181 taccaactgt aaaagttagt gaatctgata gattagatac agggaatcca agtgatgtag
    27241 tttacacaaa agatttattt acattagagg aaagcccaag attaggttgt ggtatgatgg
    27301 aaatgaaaga aacaactttt gattggactc taaactatga tgaaatagat tatgtaatag
    27361 atggaacttt agatataata atagatggaa gaaaggtttc tgcttcttca ggtgaattaa
    27421 tattcatacc aaaaggaagt aagatacaat tttctgtacc tgattatgct agatttatat
    27481 atgtaacata tccggcagat tgggcatctc aaaattaata aaaatcaaat aaataattta
    27541 aaatacaaac tcttaaataa gcacacatat ttaaaaaagc tatgaattaa aattcatagc
    27601 tttttttata aagaatgtta tattttagac gtattttttc tatatttact gggagacata
    27661 ttatattttt tattaaataa tctaataaaa tgctctacat ttggataacc aacattgttg
    27721 ctaatatcag caatagaaat atttgtatta attaacaaac tttcagctct ttcaagtcta
    27781 attctttgta ataattgagt aaaattacaa ccagcaattt ctttaataat tttagaacaa
    27841 taaggtatag aaaagtgaaa ttcattagca agttcttcta aagttatatc aaaataatta
    27901 tcttggatat aagtaagaat atgtgtgttt tttagattat ctttctttgt catattagga
    27961 acttctatac tattctcata gcctctaagt aactttgcaa aaaacaccat tattaaatga
    28021 ttaagtatat tattgtaata tctatcttgc ttactatatt ctgaaaacat ctctaaaata
    28081 gacatttcta ttgatttatc attatttgta tgaaaaagaa tatagtcgtt ctgcttgttt
    28141 ttataaatac tatataagtt tcatctttta tgttgcactt ttatacacct tgcttcacca
    28201 atatcatgtg taaccaaaat agtagactta ttctcattct taataatact ataaacatca
    28261 tcacaaacta ataatctagt ctgataatca agagctgaaa aaggttcatc taaaagtaga
    28321 atatctggat ttacagaaag tgttctaata agcgcaactc tttgtctcat acctccagat
    28381 aattcttttg gatacatact tctaaaatcc cataatccat aagtctttaa aaggctttca
    28441 actctatcta aagatttttt atcttttttg ccttgaattt ctaatccaat agttatatta
    28501 tccattatat ttctccattc aagcaaatta tctttttgaa acatatatcc aatatttcca
    28561 gtaatcttta tatcaccact agtcggtttt aaaagattag taagaatatt taatattgta
    28621 gatttaccac ttccagaagg accaagcaaa gttaatattt ctccttcttt caagttaaaa
    28681 ttgacatcct ttaatacttc aagctcgcct tccttagtgt agaagttcat atttatattt
    28741 ttaacttcta ctatgttgtc attcattatg ccacccccta taacttttag ctcgtatata
    28801 ttatgttatt aacaatatga cctatttgta ccatttttca taaatataat ataaatattt
    28861 tgtttattta cgtattttct tagtaacttg tacgtataaa ttatagataa ataaattata
    28921 aggtagggga taaatttgag taacataata acgaatttaa tagagtcaat atttactaat
    28981 ccaataacta tattgttttt acttgcaata actgtgtatt ctgtttttaa aataatagaa
    29041 aataacagag tatattcatt tgtaagttca aaattagacg aaatcaatag agactataag
    29101 acaagtgagt tttataaaaa ggtaagggat gactactata catatagtaa agaaaatcct
    29161 tatgcagacg taaatataac ttcatttata gaggaagttg tatctgattt aaagcataat
    29221 aatttgccat tgttagaaaa aattagaagt ataaaaaatt catcttcaat aagtatatta
    29281 cttggggttt taggtacgtt tgttggtctt tctacaatgc ttttatgtgt tgatactaaa
    29341 gacattataa attcacttcc ttcaactatt agtagtatgc aaactgcatt tacaactagt
    29401 atatttggag ttgtattttc tctaattata ggttacttta ctaagataaa agattgtgaa
    29461 catgttttga tacaaataat gttaaaatct gaaaatttac taacatctga aataactcat
    29521 tttaagtcag aaagaatgga tttaaaagta gaagaggtaa aaaatacaat aaaacaaata
    29581 agtaagtcta tagaagctat tgaaaaattt gataaaatat ctaaagattt aaatgacttt
    29641 aatgatgaat ttatcagtgg tatagaagct ttaaaaagcc ttttagaagg ttctcaaagt
    29701 tctattaaga catttgacca gagcgtaaga aaattagata aacagtttaa tattttaaat
    29761 ataaaatttg taaagctttt tgataaatac gataatcaag ataatataaa taaagagatt
    29821 ttatttgata taaaagaatc ttcaaaaaat atatacaatg ccactgaaag ccaattcaaa
    29881 attagagatt atataaaaaa tataaatgca ggatttgctc tatatgaaag aagtgctcaa
    29941 gatttattaa ctaaattaat gacccatgaa aataaaatat ctcaaaatca aaaaatcctt
    30001 ttagatgaaa agtttacctt agatgactca ataaaaaatc tctcaagtat tattgaaaac
    30061 ttttctaatg acctacaagt taaactggat atgatgtttg aaaattcttt agatattcaa
    30121 gataagttag atgttatgtt taataactct tttatgaatg atgaagttcc tcttgatagt
    30181 gaagaattat ttaaggatga tgttaataat gtatttaatc cttttagtga agaaatttat
    30241 gagatagagg ataaagaaat aaaggtcata ggtgaggatg agttaaatga ataataaata
    30301 tagaagaact gttaacagag aatttgaaaa gagtagcttt tggccaacat ttacagattt
    30361 attatctact gtattgatgg ttgtaattct tatcttattt agctcagaaa gtatttcagg
    30421 ttctgttgaa caagatttag ctaagaatgt caatgcttct gttgaagaaa cttttaaaaa
    30481 aagtggaata cctgtcaagg tagataaatc taatgggcaa gtaacttttg gtgaaaaaac
    30541 catgtttgat gtagatagtg atgttttaaa accagaggct aaagaaatgc taaaaatgtt
    30601 tgttccaaag tacatagaga ctatttataa agattatggt gactatatat ccaaaatagt
    30661 tatagaaggt catacagatg atgtgggaag ttatatatac aacttagatt tatcgcaaag
    30721 aagagcatat agcgttgcta aatttatagt gggagatgaa ataggtgact ataaatacaa
    30781 agataaagtg actaagcata ttattgcaat aggaaggtca aaagctgaac tcatcaaaaa
    30841 tggtgacaat agcgtgaata gagatgcatc tagaagagta gaactaaaat acgaaataaa
    30901 tattaatcaa aataaataat taaattttta taaaaaaaaa gaaggcagtt ggtgtgagct
    30961 ttaagccttc tttaaggaaa aagtttattt atttttgttg atacttaata tattatagtt
    31021 tttagaagca gtttgcaata tattaaacgt aaatggtcgt ttaaaatgca taactggata
    31081 ctactgatgt aaaatatttc attttatata atataaaaat tatacagtgt caattttcta
    31141 tattattgta ctataatcta ttatttaaaa tattatgtaa aaaaatatca taaaaacgca
    31201 tatcatgtta taattactag agtattatga atatggaggc gtagtttgtg atagaaataa
    31261 gtataaaaaa taaaaaaaat tctaaaatta aaactttgat acttttattg atagtatcta
    31321 tatcgattta tttaactggt tgtactacat cagataatgg aaataatcaa tcaaataata
    31381 atgattcttt gtctagtagt atatcaagtg ataagaatgt aaaaattcat tttattgaca
    31441 ctggaaatag tgatgcaata ttgattcaag atggtaaaac ttttatattg atagatgggg
    31501 gagataatga tgatgaggga ttaatggtag attacctaaa caatcaaggt gtaaaagata
    31561 ttaaatatct tatagctacc cattctcatg cagaccattt aggtggactt gattctgttg
    31621 tcaaaaactt taatatagaa aatgtttttg tatcgaatgg ttcagcagaa acaaagagtt
    31681 atagggactt tataaatgct ttagcaaata agggtttatc cccaagtgta ccgcttgaaa
    31741 ataataagtt ctatttagaa gattcttatt ttgaagttct aaatacaaat gggggagata
    31801 ctactaatga acaatctcta gtccttgtat atactaatgg gaatgataaa gttttattta
    31861 caggtgatgc tgaagaaggt accgaaaaag aaatactacc taagcttgag aaagtagacc
    31921 ttttaaaagt agctcatcat ggttctcgta gtagttcatc tcaagagttt ttagataaag
    31981 taaatcctga atatgcggtt cttttagtag gcaagggtaa ttcatatggt catccacatc
    32041 aggagacaat gaataaatta aaaaaaatgg gagtaaaagt acatagaagt gatgagtgtt
    32101 cagatataat atttgaatca acaggtgatg gagtatttac aagttgtaaa gatggaagtt
    32161 ataataaagg cgttagagaa gatggaaact ctggaaaatc aaacagtaat acaagtaaaa
    32221 atgattcttt taaaaataaa caaaatacat ccaattccga agaaatagta tattttactc
    32281 caaaaggtaa gagttatcac tctacaaaaa attgtagtgg gctttcaaga agtaaaaaaa
    32341 tattatcagg cacaattgca gaaagtaaga aaaatgaccc atgtgatata tgttatggaa
    32401 aataacaaaa aaacaaccaa tttatctata aagcttctga actttaaatc atttaaaaaa
    32461 taaaataaat gcataaaaaa ataagctata atcaatagat aacacatttt atctatacga
    32521 atagcttatt tttttaagta ttttttaata gctatttaat aactctaaat acaccagtta
    32581 caatacctac aatttcaact tctgagtcat tgagcataat tggttccata aaatcatttt
    32641 ctggctgaag tcttattaaa tttccttctt taaaaaacct cttaactgta gcagattcac
    32701 catttataag tgcaactact atctgagaat ttaaggctgt attttttttg tctactacaa
    32761 cgtaatcttc atctaaaatt cctgcattaa tcatactttc gccttttact cttaatacaa
    32821 aattgttact gccctttact aaactggcag ggaatggaat gtattcctct atgttttgtt
    32881 gagctaaaat gggttctcca gctgttattt gacctactaa aggaagctct attatttctt
    32941 gattagctcc agaaacatca tttactttac tacgttctaa aacttcaata gctcttggtt
    33001 tagtagggtc ctttcttatg tatcccagtt tttcaagttt atttagatga gagtgcacag
    33061 ttgaagtaga tcttaaccct acagcagtac atatttctct tacagcaggt ggataacctt
    33121 ttaatatgat ttgagacttt ataaattcca atatcaagac ttgcttttca gttagatcta
    33181 aatacataac atcactcatt tccaaacata ttttgttttt atttccatac actttatatt
    33241 tttaattata acataatcca tttatatctg caaacatttg ttcctgattt ttaatcgtcc
    33301 tcaatccatt caaaattctt gactatatca cgttttacat ttttcttatg agctgcataa
    33361 agctgagtag ttgtgacatt atcatggtca agtaagtttt gaacatcata tatagaaaat
    33421 cctgtttgga ttagagaagt tgcagccgtt gctcttaatt tatggggact atatccattg
    33481 tctctagtag tatcaagtgg aatagatgta tattttttta ccagtgttct tatagccttt
    33541 gctgtaattc tcttattttg aagagacaaa aataaagcat ctttttcttc atcatttaat
    33601 agttcatctc ttgttctttc gttttgcaaa taatctttta ttacatgttc acaagtatga
    33661 tttataggca ttaaaacttc tttcccacgt tttctatata ttttaaattc acctcttgaa
    33721 aaattaaaag aggagatatt gagttctcta agctcattta atctaagccc gtatgtaaca
    33781 aataatgcta gtatagcttt gtcacgtaat ttagtttttc tccaatatac cttttctttc
    33841 tctgtaagcc cttcacctgt ttctactgat tcaagcatct tagcaacttc atctatctca
    33901 aggcgcttaa tagcatctgg ctgaggttta ggaagtttta ttggattaaa tccatcagtt
    33961 atattattat ctatctgaga gtttctgtat aagaatttaa atagagtaga gatggatgat
    34021 ttttttcttg ctaaagctct attgttattt tcaaaaatca atgtgttttt ttctgtattt
    34081 ttgtaatatc tactgcaata atcacctaag aataaattta tatctcttga ttttattgta
    34141 ttaaaatcat cttctgtaat atcttttaca caatctgcat ttgttaattc tttggtttca
    34201 atcaaatatg aacaaaaaaa attaatatct tctaaataag caagtcgtgt agaaactgca
    34261 acagaacctt ttaaatatat aaaataatcc ttcataaata caggaagttt attttccaaa
    34321 agtagacatt tttctatgag ttcattttct ttgataacaa tattatcagg tttatctgat
    34381 ttattatgta cttttataat tttcttatca ttattcaaaa ttaaacctcc taaaactaaa
    34441 atataaatct tttatattat tttttgatat ttataccaag tgagtataaa tatttaattt
    34501 aatcattttt tacattttta agagattagc agtgctttag atgaaattat cactaactat
    34561 tccctaaatc cacatttaaa gactagttga atttaagtac tcttttttat ttctcaatat
    34621 atttatagaa atattttaaa atatattgag aaatttttta tgctctacta aaatcttttt
    34681 tatataatat ttttatatgt ttctaacgaa accaaatatt agtaaaatat gtatttattt
    34741 aactaaagtt tttaaatggg ctgactaagc ttaaaatata ggatattatg agagttacta
    34801 ttgaaaaaat aaaccctatt gccataaaga aacttataaa tatgttatac ttaactatta
    34861 aactggatat attcaagtta tcaaatccaa ataagtatgt aattgaactt attacaaaaa
    34921 taactataac tataaagctc agaccattta agctattttt taaatcagca ctactaagtg
    34981 acatatgtgt agatatagaa tacattaaaa acataaatat aaaatacttc aatgaatata
    35041 cactaggtgt taacaacatt attcttataa aattggaaat atcacctaaa ataatgtgta
    35101 taaaaccatt tatatttaaa ttattaatca tacttacata taactttaaa tctatatttt
    35161 gagtcacttt catataacta tctggcagta atatcttaaa aattaaaata atcattattg
    35221 ttccacctat aataggtgca attcctataa agaaatttcc tatactttga taaagattat
    35281 cttttttata gctatgactt acatatccta gtataccatc atttttactt tctattggtc
    35341 tgaaaaattt aactgaattt attttatgca tgaaaatcaa acacattatc aaatgactca
    35401 attcatgaac aaacgttcct atagctccag ttacaataat tccagttttt ccaaaagatg
    35461 aaaagataaa tttattattt agattttctg taatgctaaa aatcaatcca aatacaataa
    35521 atattcctat gaaacaaaaa atatttatta cacttatttt taaaatttcg attatataaa
    35581 tcataagtta agtcctcatg taaaagtatt taactactct acttcatatc cattacagct
    35641 taaaatttta caagcatttt ctatatcttt ttcttttact aagatatagt ctgtatcata
    35701 cgtagaaatt gcaaatatgc ttattttgtt gtctgctaac aaactactta acttagataa
    35761 aattcctaca agtgaaaagt ctaaaggacc tagtatctta agtattctcc actccttttc
    35821 tgacttgaca tcagaaggaa tattattatt taaacataca acacttaatt catcatcagt
    35881 tctagttata gagtaaaact tctctgtatc tatccatgtt ggtattttac tgtcattatt
    35941 taatctacat actgcatact cttctaccaa taattttaat ttcataatgt atatttcctc
    36001 caatcttatt tgtttactta agattataca ttaaaagtta cataaaataa aacatataaa
    36061 gtaaaaaagg ttcactatag tgtcctattt ctatagccaa cctttaaaac ttaattaaat
    36121 tctaataaag agatatatta tctaggttca attataagtt taatggctgt tttcttatca
    36181 ccttcgattt ctatatcagt aaatgcggga atgcaaacta aatccattcc actaggtgca
    36241 acaaaacctc ttgctattgc aattgatttt atcgcttgat ttagagctcc agctcctata
    36301 gcttgtattt ctgcaacgcc tcgttctctt agtactccag ccaaggctcc agctacagaa
    36361 ttaggattag attttgatga aacttttagt acctccattt caacatctcc ttgttaattt
    36421 gttaaagtat ccattaccta aagtactaaa tcataattgc catttactaa ttacaatcat
    36481 catttaaagt atacttttat aaaaatatac ttctataatc gttttaagaa aacctttatt
    36541 ttttttaacc attttattat gaaaaaacta caaatttctt tatattctat aagcattttc
    36601 caatatttct aaatttttta tatctttgag ctataatttc ctctttatcc atatctttgt
    36661 aatgatttaa tctttctaaa atataagctt ttatttcttt tgaaacagct tctacatctt
    36721 tttgtgctcc tccaagaggt tcttttataa tcttatctat tatttttaaa tcatataaat
    36781 cattacttgt aagcttcata acatcacaag cttctttagc tttagatgaa tctttaaata
    36841 gaatactaga aagcccttct ggagaaatca cagaataaac tgaatgttct aacatacata
    36901 catcatttcc tactccgata cctaaagctc ctccactacc accttcacca attacaaaag
    36961 tgattactgg aacagaaagt ttactcattt caagtaagtt tcttgcaata gcttctcctt
    37021 gtcctctttc ttctgcttct agaccacaaa aagctcctga tgtatcaata aacgttatta
    37081 taggtctatt aaatttttca gcttgtttca taagtcttaa tgcttttctg tatccttctg
    37141 gatgaggcat tccaaaattt ctttttatat tttcttttgt atctcttcct ttttggtgtc
    37201 caactatagt aacattaaac tttcctatct gaccaattcc tccaaccata gaagggtcat
    37261 ctttaaaaag cctatctcca tgaagttcta aaaaattaga acaaatatgt tctatgtatt
    37321 ccaatgtcgt aggtctcttt atatctctac ttaatgttac cttttcatat gctgatagat
    37381 gtgaaaaagc atcttcctta agcttttcca atttctcatt aagtgaattt attttatcac
    37441 ttaaatctat attatttgcc ttagaaatag ttattaattg tttaatatca ttttctaaga
    37501 cttttatttt ttcactatta ttttcaatca aaacagttcc tcctttatgc cctatttctt
    37561 gtgcatagca agaatttgat ataatacttc cttcattttt cttctatcta ctatcatgtc
    37621 aataaaacct ttttcaagta aaaactcaga agtttgaaat ccttcaggaa gtttttgatt
    37681 tattgtttgc tctattactc ttggacctgc aaaacctatc aacgtatttg gctcagaaat
    37741 tataatatca ccaagcatag caaaactagc agttactcct ccagtagtag ggtcagttag
    37801 aactgatata tatggcaatg atttttcttc aagcttagaa agtgcttgag aagtctttgc
    37861 catctgcata agagatacca taccttcttg cattctagct cctcctgaag cagaacaaat
    37921 aattataggt aaattatttt cagcagcata ctctattgaa taagttattt tttccccaac
    37981 aatagaaccc atacttccca tcataaaatc aggattcatt acacaaataa ctgttttaat
    38041 tccatttatt cttccataac ctgtgacaac agcttctgac tcttttgttt tttccttata
    38101 agagtctact ttttctttgt atttaggaaa atttagtgga ttttgaaatt ctacatcaga
    38161 attaaactcc ataaaagttc ctttatcaat caataaattt attctttttc ttgctcttaa
    38221 gccataatgt cttgaacatt ttggacatac aaatgaattt tcttctatgt cctttctaaa
    38281 tacatgacta tcacaacctt tgcaataggt ccaaaattta tcatctacac tattcttttt
    38341 aaagttgtca tctaaagaaa tcgtaacata cttagattct tttgatgata aaaatttttt
    38401 tatcataatc tatttactcc ttataatgta gcaaattctt tcttcataaa gacatcttct
    38461 ataaatttgg tatgatgagt atcttctcta aactcctcac ttgttacaag tgccttttga
    38521 aattctacat ttgtattaat accttctaca ataatttcgt ctagagctct atatattcta
    38581 cttatacatt cttctctagt ttcagcccaa catattaact tacctatcat agaatcatat
    38641 aaaggtggta tagtatatcc tgcatataca aaagtatcaa atctaacacc aaaacctcca
    38701 ggtaaattta atgattctat cttacctggt gatggagcaa aattctttga tgaatcttct
    38761 gcatttattc tacattcaat agcatgacct ctaaaagtaa tatcttcttg tttaaaagga
    38821 attttatccc cattagctat agatatttga agttttataa ggtcaagatt tgttaccatc
    38881 tctgtaactg gatgttcaac ttgtattctt gtattcatct ctataaaata aaagttttta
    38941 tctttgtcaa ctataaactc aatagtacct gcaccgatat aacctactcc ttttactata
    39001 tctactgcaa ttttatgaag tttttgtctt tcttcatctg aaaggtatgg acttaaagat
    39061 tcttctatta ctttttgatt tcgcctttgc atagaacaat ctctatcacc taaatgtatt
    39121 gcatttgaat gtttatctcc aaatacttgt acttctatat gtctaggatt ttctataaac
    39181 ttttccatat ataaatcact attagaaaat gctgctagag cttctgaact tgccatatca
    39241 aaatttgaaa aaagttcttc ttcttttcta acgattctca taccttttcc accgcctcca
    39301 cttgaggctt ttatcataac aggatatcca atttctcttg caacttctaa agcttcttcc
    39361 ttagttttca aaacagattc tgaaccagga acaacaggga tattcaattc catcatagtt
    39421 tctcttgctc tagatttatc tcccatcaaa atcatttgtt ctcttgttgg acctataaaa
    39481 ataatattat tatcttcaca ttgctttgca aattcaggat tctctgataa aaatccaaag
    39541 cctggatgaa tagcatcaca ctttaattta agagcaagat agattatatt ttctatatta
    39601 ttataactct tacttatatt atttggtcct atacaaatag attcatcagc tatatatcta
    39661 tgaaaacaat ctttatctat ttcagaatag atagcaacag tttttatacc tagttcttta
    39721 catgttctga tgattctaac tgctatatcg cctctatttg caactagtat tttttttatc
    39781 aacttaaata cctcctacta caatggtttt atcttaaata aaggttgatt atattctact
    39841 agttcttcat tactaactaa tacttcaatt atttcacctt taatttcact tgttatctca
    39901 ttcataagct tcattgcttc taatatacat aaagtgtcgc cttcttcaac tacatcgcca
    39961 actttaacaa agctatctgc atctggactt ggagaatcat agaatgttcc catcaaagga
    40021 gctactacta ctgatagatt ctcattagat gtgacaggtg tatcgtttac aactggcttt
    40081 tctaaagaaa gatccactac tgattcttgt tgtacactta aaacaggtga acttgtagat
    40141 tgagcttttt tagatacttc taatcttaaa tcgctacttt caagttttac atattctaag
    40201 ttagttgagt ctatggcctt taataattcc ttaatttcat tgatgttcat tttgttaccc
    40261 ccttgtatta ttacctggtg ctaatattat atcacaaaaa acaaatttat aaaagaaaaa
    40321 gtgctgacta gagaatcaac acatcaatat atcttttaat tttaaattaa caaccagtaa
    40381 cttatatttg ttttaatttt ccattattaa tataaattat aagtataaaa tgaataaaat
    40441 tcaatatttt ttgcaaaata caagagaata caaattaata cctcgggaat ttttaagaca
    40501 aataccaata ttatgcaatt tagacttcgc tttctttcaa attagtatca ttttctttat
    40561 ttttacatag gatgtacttt aatttagcta tcaaaacatt gctatatagg ttaaaagtta
    40621 ttagaattgc aggaattata aagtaaactc tagcacctat aaaaccaaaa actactgtaa
    40681 taagtattaa tcttttattt aaagtaaaaa aaggtatatt gaaaatactt ttgtcggatg
    40741 tttctggagt ataagaatat ataactccaa aaatcaaagt aagcatacaa agtggaagta
    40801 gtgtataact tgaaattatt cccagaaatc ctatactttc aaaatatttg ctagcactat
    40861 ttgtataaac aaacatgtat ccatttaaat atgcgcatat acatgatata atgccaaaag
    40921 ttccccctaa ggattgagtg taccaattaa aaaatttaga ttccatatac ctcacctcct
    40981 aaaactgtat atataatgat atgcatttaa atagtaaaat atatctttat atgtttctga
    41041 ataaaatttt gttaatttca ttaatttatg tttaagaaat ttgaagtata gtgtagtata
    41101 tattaatgta gatgaagttt tatagtactt atttcatagt gcttaatcaa gttatcttat
    41161 tatggattca aaagttgttt gtagggtttt atattttgtt gagctgaaaa atttattata
    41221 aatgaaggga tgttttcgct ttggtagata cattagaatt tggtcttaaa attttatttt
    41281 ttatattatc aataatttgg atgggtaaaa taatgatttt aagaactgat aagcaaatag
    41341 taatcaatcc tttgcttatt ggtatatctg cagtccttgt gatgttgcat acctcacaga
    41401 gtaacattga attttttgga ttagatgtcc aatatataag aatagttttg tatataatat
    41461 attcactgat aattttaata ggaatatggg ctactaacag aagaaatgga attttttaga
    41521 taatctattt ctataaaatt taaaggttgc tagtaacaaa gcactaatat tagcgttctg
    41581 ttactaacaa cctttatttt gattatacac ttaaattgaa aatagaatga ttgaataagt
    41641 tgacagatta ttttacattg acagtaatta gaacttcttg agatgtattt aaatcatttt
    41701 tgtcgcttag tataactttt accactgctt gacctgtttt attaccttta attatcatat
    41761 cttcacatga aagtacactc ttatcactta cagatacaat aaaatttaaa tcttttggaa
    41821 ggttatcagt aacttcccag tatttataat aactatcaat tttcttcgta attatttttc
    41881 tcaaatcaat actttcacct tttgctatat caacattatg atatttagag tccagtttat
    41941 actgattatc ttttgtatca ataaaattta aatcgcaatt tacatccaca ccattatgag
    42001 aaagagaatt tactacatcg tcatcaatca aataattatt ggcaagattt attgaatcca
    42061 tatcttttag acttaaagct tccttaggaa cctcttttat attattattc caaaaaataa
    42121 aattgtctac attttcaaga tatgatattc cttttaaatt tgaaatactc tcaccagttg
    42181 cataaaattc tccatctaaa gcctttatat tgcttatagt catctcatct ggatttatat
    42241 atctttttac aactgctctt aaatttgcat caggaaaaat atctttaagt tgattttcgc
    42301 tcaaaacctt atcatttgaa tttattggac ttaaagctgc tgcagaaata ataaatggta
    42361 ttaaattagc taaattcata gtaccctccc acataaattt tttattataa taatttaatt
    42421 tctatgagag ggttctgttt ccttgttata tatacctact ttcgtacact ttattaatat
    42481 aaattaaaat aaatttctac tattaaactt ataaacatat tactagttac gttttttagc
    42541 ttcacatcta aatattcgca taccttgtga cataaatttg tcttcatact ctgttgtaac
    42601 attattttca tactcactat ttcctaaatc aagagaaata ttctttaata gccaattatt
    42661 tgcagcaatt tcatttaaac taaactcgaa taatttttca ttatctgttt taaagtgaat
    42721 ttcgccatca tcttccaaaa ccctattgta catttctaaa aatccagaat gagtgagtct
    42781 tcttttactc catctatttt taggccatgg gtcacagaaa tttatataaa ttctcgataa
    42841 ttctttagct tcaaagtaat ccaaaatatt gcttacatct ccccataaaa atagtatatt
    42901 attcaaatta gaagcatctg ctttttcaac agcctttaaa agaacttctt ccttaagttc
    42961 catggcaata taatttatgt cagggttctg cttagctaaa gttgttataa acttaccttt
    43021 tccagtccca aattcaacat gtattggatt atcatttcta aactttaaat tccacttgcc
    43081 ttttaatttg tctatatcgt ctcttaaaac atattttgta taacttaaaa gcttttcatc
    43141 tgaacctttt tttcgtcttc ttctcacaat aattctcctt acatataaaa aattagtaaa
    43201 atacattttt attatacatt atctcaccaa aaaataaaaa gaactctctt aaaatagaaa
    43261 tttatttcta taaagagagt tctaaactta ctaaaaactt aatcttagtg gcaccctgaa
    43321 caaccagagc atcctcctcc accttgatct ttcatatttt caggaataac tctaaatcca
    43381 aatcctgtat cttctattat tatatctcca tactgactat attcatcaga gctcattaca
    43441 aattgtaact ctccaacttc ataagttaag tcatcttctt ttttctcatc taaagctaat
    43501 ccaaaagaag gacctccaca accaacacct gcaaagtata ctcttatatt attaggttta
    43561 tcttgattgt cttttaagat actttttaaa gtatcaatag ctgtttctgg taaagtaatt
    43621 ttcatcaaat cattcccttt caaatatttt attaaaacaa tatctattat atacccatac
    43681 aaggtacata atcaattagt ttttgcatat tttactaaaa cttctaccta atattaccta
    43741 aggctttaaa atattttata taatatttta ttaccttaaa taaataccct atcataaact
    43801 tagtaaacaa ataaaattat tattctaaaa aatataataa ttttatttgt tgttttaata
    43861 ttataacaca tttgataatg tacaattcat atatgcaaaa tttatatact ttaaaatatc
    43921 taagaaatta ttcaataaaa aaatactatt ttttaaaaat tatcattatt gataaagctc
    43981 tactatttat attttttagt gtattcatgt ataataagta aaagcacaac ggtatatact
    44041 gttgtgcttt tttgtaatta ataaacaata ttttggtcta taacaatgaa aaatggctac
    44101 tttccataat tgatttcatc tgacataagc aaaaagggtg tccagctggg tcaatcataa
    44161 ctctccagtc atcagtaaat tgctcctctg cgattgtagc tccacaatga attgcatatt
    44221 gaactgcttc ttttaaatca ttaacagcga aatccatatg agccatttgc tgttgagatt
    44281 caggtttttc tggttctatt atgccccaag cctttgtttt ttgcaatata gagaaaaaat
    44341 tatatatttt aatattttat aattgttgaa attgtgtaat aaattcaact ggatacatag
    44401 tgcgttttga aatttcttct aaagctaaac cttgttttaa aagcctcttt atgacgcttt
    44461 ccatactttc tgaaatttct ataatatttt tatcaaaatc ataaaaccta aaagttcttt
    44521 gaccccatgg gtattctttt atataatgca aaaattcaat atttcctatt ctatttatct
    44581 tactttccca ttgtttgatg tcattaacct caaaatacaa ctgaaagtta tttgattgtt
    44641 gatatattgg taaatcatat ccaattatag ctttataatt actttgtaat ccaaatccat
    44701 tttcaaatga tacatgttct cctaaatcta atgtgatttt ttgctccata acatcttcat
    44761 aaaacttttt tgatttattt atgtctttga caattagcaa tactcctcca aatttcatct
    44821 tatcactatc ctttctttgt tataagtatt ataacttaaa attttgcaat ttcactgtaa
    44881 aaatcagaca tattagctcg gtatttttga ggagttattc cacagacaat tttaaaatct
    44941 ttaataaaat gtggtatatc atagaatcct aattcattac atatagacat caatgaagtt
    45001 ttattattgt ttagaagttt tatagattta ttaatacgta ccaaacgaga aaatgacttc
    45061 atactcaacc ctaggtactg attaaagagt ctgtttaaat gtctagaact ataaaatact
    45121 tttttagaaa tttcttgtga agatatattt ccagagtttt gaataatcaa ctgaattgcc
    45181 aaaataaact catatgagta ttcaatttta atattagaaa tcaataattc ttccaacttt
    45241 aaaatcaatt tatctataga taaagattca ttaaatattt ttttaatttc taaatctaat
    45301 gaagtattaa ttatagaaaa tggaacaact ttatcaataa gttcactttg ctgtatacct
    45361 ataagcggga aaaaaccagc aggttgaaat tctataatta gtataacatc acatctatta
    45421 gcaatatttc ctactgtttt tggtttagta gttggaccaa ataatagact atgtaaccct
    45481 gtggcatcat aaaaaaacac caaagttaca cttccatgag gaataatcgt gtaattatca
    45541 gaaattattg tttgatttgg aaacgatata gtaaaattcg atatccaatt tcttaattgt
    45601 atacaaggca agagataaac aaaattgtct tcacaaacta taagtgacct atttttattt
    45661 ataaaatgaa tactttcttt ttttaacata tattatatcc tgtcctatcg tgaatattta
    45721 ttaaagtaag aagaatccat attatctcta tatatcatta actgctttta ataatagaga
    45781 tagtatgaat actcattaga tatttaataa acaaataaaa ttaaaataat caataaaaaa
    45841 tatagtactt ttatctgtta ttttaatatt atagcacatt tatagtattt aacttatatc
    45901 cactttacat atgtctaatt tatatagtta aaaatgctta tctcaaatac aataattact
    45961 ccttatacaa ttaaaccatc tgaaactgta atagtacgac tactactttt ggctgcttct
    46021 ggtgagtgag ttaccataat tatagtttgt ccattgtctc tgtttatttt attcagtaaa
    46081 tctattattt ctatccctgt tttactatct aaatttccag taggctcatc agcaaataaa
    46141 atctctggtt ttccaattaa agctcgagct atagcaacac gttgttgctg accaccagat
    46201 aactctcgtg gtgtatgttt acgtctatca gttaaaccaa ctatatctaa gatttcatct
    46261 aattgatttt tataatcttt taaattttta ccatctaata acaaaggaag cattatattt
    46321 tcctccacat ttaaatttgg tattaagtta taaaattgaa atacgaatcc tatatttcta
    46381 cgacgtatta tgctcatttt ctcatcatta aagtgtgata tatcagctcc attcatatac
    46441 acttttccgc tcgttggagt atctaaacca cctaaaatat ataaaagagt acttttacca
    46501 gaaccagatt gacccatgat agaaacaaat tcacctttca ttacttgtaa agatacctct
    46561 tttaacactc gagttgttgt atttccaatt ttatattctt tgataatatt ttttgcttct
    46621 acagctaaac tattatgtgt aattttcata ttaacctcca taattattca aacttaattt
    46681 cttctatcag tttcattttc ttccctttta taataggcac tatcgaacct attaaagtta
    46741 ctataattcc caataaccca acaataataa atgttttaaa atctaaatct ggtttcattg
    46801 aaatttttgg tcctgcaact ataaagatag tttgaatctc aagtatagat atcacaatac
    46861 caataacagc tccaagtaaa cctgaagtaa acccttcaat caatgttact tttatatttt
    46921 gtttatcact tagtcctata gatttataca tagctataga acgtcttttt tgaatataat
    46981 taatcagtag attattaata atacctactg tagcaagaag aaaaatgaaa taggtcatct
    47041 tattcatagg agacaaaaaa ctacttatag tatttaaaga atcattatta aattcttcaa
    47101 ctgtacgact ccaattatat gtatctccaa ataaatatct tatctgaatc ataacagcat
    47161 ctggattgac tgctgtatat actaaaaaac cataattagt tttatcaaaa tcattaactg
    47221 cataatgtga tggtataaca gcttctacat catttgcacg ggatttaaaa ctacctacta
    47281 ttttataaga aaaatcatac ttatcattag atagagttat tgtatctcct atagataagc
    47341 ctactttttt tagagtatct tcattcaaaa taacagaacg tttatcatta aaagcttcta
    47401 ttacttgttt ttttatctca aaatttgtat aattgattcc aaacatagag ttatatagtt
    47461 ttatattatc tgtaccctct agtcttgata atgttacacc attaccagaa atctcattat
    47521 tcataacata aagaggtaat atttttttaa ttccatccat atgtctaaca tcttcaataa
    47581 actcttcatt catctttcca tctgcaaaac cttgtaattc tgcgtcacga aacacatctg
    47641 ttatataagt tttaacaaag ttaccaacaa cacttattgc aataactgca gaaatactta
    47701 taaatagtaa agtgatattc tgtattatat ttttgttatt tttcatattt ctagcagcta
    47761 atttaccctc attccctaaa atatttttat aaacaaactc aaaaactata gacatgatat
    47821 cagtaataag aggaatcaac acaatagtag ctacaattaa tcctagtaat gaaaatccac
    47881 cagctagata caatgtattt tcaggggata ttcttggaag taaaatagat aaaataaaca
    47941 ttatacttcc tataaaaagt atagaacgat ttgaaacatt cttttcttct actgttccta
    48001 gtacaatatt ttttatcggc aaatggctag cttttttaac aggtatatat gcactaaatg
    48061 aagaaacgat tattgctact ataacagata taatcactcc aatgggtgat attactactg
    48121 gaattgatat tccttgctcg agagaatttc ctaacccatg aagcattaaa tttaaaacaa
    48181 ctacaccaat aggaatagca attaatcctc ctatacttcc gtataatata ctttcaagca
    48241 tcaatatacg agttacagtt ttttcattgg caccaatact tctaaatgtt ccaataaaag
    48301 gaagacgttc taatgtaata accttataac tgctgtatat tataaatata ctaagggtta
    48361 atgcaaaaaa acttattaaa aagaaaggca ttgtcttttg tctagcatct gaaattatct
    48421 tagtttcatt tatagtattt gataccatat atttttcagt agaaagttct tcggataatt
    48481 tatttactag attttctgta atttcttctt ctgactctat aagaactctt gtatatccac
    48541 tgcctttatt tataattttt gatagagtct ctttgggtag tagtgcattt acacctcttg
    48601 tgttcctcaa aaatactgta tcataagatg caatatcact aacttgaaaa gtataggact
    48661 ttccataaat ctgtaaagta atagaatcac ctttttttat tttatatttt gatgtaaagc
    48721 gatttggaag aataatttta tcaccagaaa aatcagtaat actatcgcca ttttctaatc
    48781 gtggcttgtt gattttattt agttgactta agtctgctga tataagacta aattcttcat
    48841 agtatccccc tttattataa atagcagagc tttccaatac accaaccttt gattttatag
    48901 catttaaatc aggtatgtct tctaaattgg ttaatatatc tggattttta ctttggacag
    48961 atatagtcgc tgtaccatac ataccttttg ccatttttct ttgtgcactt tcataagata
    49021 atccaattga gaatgaaaca aaaagtaaaa ctgttgataa aactatggac aataacataa
    49081 ctgctgttct aatttttcgt tctttaatat ttgtgaaaat atactttaat ataattttca
    49141 aatttacacc ttctttcctt atctaagata tttcaatcta atatttttat actttaatct
    49201 aaattaaatc tctaatagac tcctccatac ttttatcatt ctatttataa tatttttaat
    49261 caaatcaccc cttaaataaa aaagattgat aaactactat ataaatataa taatctatca
    49321 accttaatat attttttatt taaccttaat taaccttaat taaataggaa aggtgatata
    49381 aaatgagcta cctaatccag gtatactttc aacagatata ttccctccat gaacttcaat
    49441 aatttgcttc gttattgcta gtcctaaacc agttccttct attttttgtt ttgtattgct
    49501 tcctctataa taacgattaa ataaatttga tgcttcttct cttgacatcc cttttccatt
    49561 atcagatata atgatttcaa ttctttcatt taattttaca tgtacacaaa ctttagtatt
    49621 tttatctcca tatgtaaaag cattgacaat aagattacta aaagctcgtt ttaatagtgt
    49681 acaatcaaaa tcaaagttaa tattatctat attactctta aattcaacta tatttgattc
    49741 atattctgga taatttaaaa tatcaatgga taattctttc aagaatctta ctaaatcata
    49801 attattttta tttaaaggga ttattccatt ttttaattga taggttaatt ttaaatcgtt
    49861 tataagtgta tttgtatatt ctatattctt taacatgatt gaagcatatt tatatacttt
    49921 ttcaggtgaa taattagtac tactatctgt aagaagctct gcataccctt ttattggtga
    49981 aagtggagtt tttaaatcat gagttatatt tgaaatccac tcttctctca taatatcagt
    50041 tttattttgt atctcatcac ttttatgaat ttcttcattt aaaatattta aactattata
    50101 tatatcagca aaaacacctt taatattaac tggaagatag cttcgttttg aaatatcact
    50161 aacagcagat gtaatatttg atatgcactt tgttacccag taaccataag caattccaga
    50221 aaccaaaatt attaaaaata taatccctat gattgaaaat acaattgact taccacctat
    50281 aaatttacct ccatcaaaaa acatattcac tttagatata tttaatggaa aatatataat
    50341 ataaatatag tcatttttat tatttttaat tgtattaaag tatacagttc cattacttga
    50401 attattttgg ttagctaatg ctaataattc agaattagaa taataatctt tatgctcttt
    50461 tggttctaaa aacccataaa ctctatttcc actagaatct aaaatttgca accacaattg
    50521 attttctcga agtttttcta atccagactg ttttacttgt ggcttattat ctataaatac
    50581 gatttgttca ttaaagtttt ctgtaaattt tttcggccag tcactacgaa taaattcccc
    50641 atttggtttc tgaatagtaa taagtgataa gaaaatacct attactgtca ggattaagca
    50701 aataaaaatc atgaaaaaaa taatgtatga atgaaatact gttttataac taggtttatg
    50761 catttaatca actcttttct taaactttta ttttagtttg attgttgctt atataaaata
    50821 gacaataatt attgatatgt aaaaatttat ttaaaaatac aactatctac ataaattata
    50881 tttatataat tatatgttat caagctgtct gttgtattta ataaatcttt ttgataacat
    50941 ataaaagtaa gataaatttt tccattaaat accttataat tatacacaaa atctctatat
    51001 acgttaaaca atatagagaa aattttcata gaaccatctt tataggggat actttataaa
    51061 agaataaaaa aattataata tataaaaaac ttcataggag tgtaacaaca tcagtaaaga
    51121 tatgaaaaca ctatataaaa attcaaaaat attaagaata atgaaatact tgaaattgct
    51181 tatatcaaga aattttatat aatataaact ggtcaaatat gttataatat taaattgtga
    51241 caagttcatg gaggtgttta tatgaaaaaa caaaagtcgc caattttact tgaaatgctt
    51301 ggactatttt ttggttgtat atcaatgagt attggtataa atatgttttt aaaaccacat
    51361 acaattgctc ctggaggact tagtggtcta tcattagtac taaacaaagt tacaggactt
    51421 ccagtatcag ctatcatgtt aattataggt gtcccattag taatacttgc ttttagaatt
    51481 atgggtacaa aaaattcatt aaaaacttta tttggaacag ttgtattttc agctatagtt
    51541 caattaacag acccattatc aaaactaaga tttactaatg acttattatt gtcttctatt
    51601 gcaggaggaa tcctagttgg tataggttta ggaataatgt ttaaatcaga tgcttctact
    51661 ggaggaacag acttaattgc actcatactt agtaagaaat tcccaggaat aaaagctaca
    51721 aaattcatgt catgcctaga tggaatggtt gttatatctt ctggtatagt aaatcgtagt
    51781 ttagaaactg ctctttactc tggtatagca ctttgtgtat taataaaaat agcagatatg
    51841 ataatggaag gatttgacca ttcaaaagca ttttttatta tctctgatga gcctgaaagt
    51901 ttaagacaag ctataactga agaacttgat agaggtctta ctattcttga tggtaaaggt
    51961 ggatacacta gagaaaataa agaagttcta ttagtcgtag tttctaaaaa acaagaactt
    52021 tatctaaaga gattagttaa aagaactgac cctactgcat ttgttattgt tacagatgta
    52081 catgaggttc ttggagaagg atttaaaaat ttagagaact aataaaaatt aatattttaa
    52141 gtatatatac tattttaatt aaaatacgat ttattcaaaa agagtgtctc atgaactaaa
    52201 aagtttatga gacactcttt tttgtataaa atcaaatgca ttttcagtat tttaacaata
    52261 aaaacaggat tatctatatt ttgaggcaac cactttattg aaattttatt tagaaaacaa
    52321 tcattactaa ataaccagca tagatattaa atgattatat ctattgtttt ttcaattcat
    52381 attgataaca aggaacattt tttacagtat ttccagtatg aatttttttg atatactttc
    52441 ctgtacattt aaatcctaat aaatctaatg attttgtaga attttggttt tcttcatagg
    52501 ttattgcaat tattttattt aagtttagtt ctctaaatcc atactgtatt actctttttg
    52561 ttatctcagt agcaaaatca tgtccccaat agctcggatt tatacatata cctatttctg
    52621 cttctaatgc tttaggattt atattattaa accccatatt cccaataact ttattgtctc
    52681 ttttatatac tatagcaaag tggccaattt tccctttttt atatggattt agaaaaaatg
    52741 attttataaa ctttcttgta tcttctaaag atttatgctc actaaatggt aaatgtttta
    52801 ctactatttt atttttataa cagtcaaaaa aatcttcaac atcatctaat gatgcaggtc
    52861 ttagtataca acttctagtt tctaaggttt tcatttgagg atattcagaa tcagacattt
    52921 ctaatccccc tttatacatt aatctaaata tactgttcat atttaaaata cgatattaat
    52981 tatataaatg ttctcaaatt aaccttattt ttatttttaa taaaaactaa ttactatatg
    53041 aatctttcaa gtttacgaat ttatctctat ttttatatta aattacttgt gaaatatgta
    53101 ttctaaatta tatattatta gatatcatgc ttaaaaattc tttggttgct aaggataaag
    53161 atatatcttt taaatggcag taacctatat ttctcttagg tattggctct tttatatcta
    53221 atttaaacaa tttctcattt tccaaataat ctatgctaaa ttcttctata acacaagaca
    53281 ctccaagatt tatatacgca aattctaaaa gtaattcatg agaacccaat tctatatctg
    53341 ggtttagttt tatacctttt gataaaaaat attcatttac ataaagtctt gaatttgctt
    53401 tattttctag cattattaaa ggcaatgtgt ttaattcttc caatgatatt ttcctacctt
    53461 tgtattctat gtaatcattt gcacatacaa atatatcatg tatttcaata cactcaacaa
    53521 tatttagtgt atcatcttct attggcatgt ttataattgc tatatctata ttcccatctt
    53581 tgagtaaaga tataagttct ctactcgttc tatttattgt agatacatgt atatgtggat
    53641 acttcttatg aaaaatttct aaatatttta acaagaaaaa acgtgcagct gtatctccta
    53701 ctcctatttt cagagaaccg tattctaatt ttttaaattt atttattcta tcttctcctg
    53761 atgatattaa ctttaatgca gtagtgacat gttcacttag aattttcccc tctggagtta
    53821 attttactcc cttattgttt ctataaaata ataaagtatc taattgttct tctaattgct
    53881 ttattgactg gcttacagct ggctgtgaca taaacaattc cttagcagca agagaaaagc
    53941 tcttattatt tacaactgca ttaaaaacct tataaagttc aagttttata ttcatatata
    54001 attactcctt atgtcaaata ttagtattat ttattttact tataattata tttgaattat
    54061 aatatacatg gtactaatat gacaatatta attctttagg aggattttag ataatggata
    54121 gattagttgg aactgtttca agaggggtta gagcacctat tataagacaa ggagatgact
    54181 tagttaaaat agttgttgat tctgttttaa atgcgtcaaa aagtgaaaac tttgaagtta
    54241 gggacaaaga tgtaattgcc gttacagaag ctgttgtagc tagagcacag ggaaattatg
    54301 ctcacgttga caatattgca aaagatgtaa aagataaatt tggagatgat actgttgggg
    54361 ttatattccc aattttaagt agaaatcgtt ttgctatatg tttaaaagga attgcaaaag
    54421 gatgtagaaa agtcgtatta atgttaagct acccttctga tgaagttgga aatcacttaa
    54481 taagtattga tgaacttgat gataagggaa taaatccttg gtcagatgtt ttaacagaag
    54541 aaaaatacag agaactattt ggatataaca agcatacatt tactggtgta gattatgttg
    54601 attattataa gaatttaatc aaggattgtg gtgcagaggt agaaatagta tttgcaaaca
    54661 atccaaaaac tattcttaac tatacaacaa gtattttaac ttgtgatata catacaagac
    54721 aaagaacaaa gagaatttta agacaaaatg gagctaaaaa agtatattca cttgatgata
    54781 taatgacagc aagtgtagat ggtagtggtt acaatgacca gtatggactt ttaggttcaa
    54841 acaaagctac agaagaaaca gtaaaattat tccctataaa ttgtgatgaa gttgtaaaca
    54901 aaatccaagg taatataaaa gaaataacag ggaaagatgt agaagtaatg gtttatggag
    54961 atggagcttt taaagaccct gtaggtaaaa tatgggaatt agctgaccca gtagtatctc
    55021 ctgcttatac aaaagggcta gagggaactc caaacgaagt aaaattaaaa tacttagcag
    55081 ataatgattt tgctgactta tctggtgatg agttaaaaga agcaatttca aaatacatag
    55141 ttgaaaaaga taataaatct gatgatttaa caggaaacat ggtttctcaa ggtactactc
    55201 caagaagatt aacagacctt ataggttctt tagcagattt aacatctgga agtggagata
    55261 agggtactcc tattatttac atacaaggat atttcgataa ctatacaaaa tagtatgttt
    55321 taataagatt taaatttttt ggattatata tattaacatg aaaatttatt aaaacctctt
    55381 aatagatatg acttttcaag agttatatct attaagaggt ttatttaatg ttcacagata
    55441 agatatattt aaataattta aacaagattg tcagaaagtt atataatctt aaaaatttat
    55501 ataactctaa ttcttattta tttctgaaat aatatcactc ttcaaaattt gtcttactgg
    55561 aataattaca gcaactatac taatagtgat atttaaaata atcataccta tgtatagagg
    55621 tgtatttatt ttaagaattg gatttatata taagtataca cgttttacca taaaataaat
    55681 cataaattgt ccaataacac ttccaattac cattataata cttgcataga atccatataa
    55741 aaaaccttct cttatcatca taagtaaaaa cttattatcc gtaataccca tagctcttaa
    55801 aattccaaac tcatgtcttc ttgaaaaaat taagtagctt actgtattga ttatatggaa
    55861 caaacttatt gcaagaagta caaatacaat accatatata aataagagtt tttgatttaa
    55921 gtaggtatta tttttttcaa tagcaatggt ataatctgtt acgatacatc tttttacatc
    55981 acttacaaca ctttttatgt tctcagacaa ttcctcactg ttactatctt ctgtcttttt
    56041 tatacttact gaattataat tttcgatatc aaagttattt ttcatttgac cattcgtcat
    56101 aactatatcc ataccataat caccaatgaa atatatgtta tttgccatca cacgttttac
    56161 agtagcagca actacaaatt cttttgttgt ataatcattc ttattttctt ctttaaattt
    56221 aacaatttca tctgttggtt tcattgtctt tggcacttta acttttattg tatctcctgg
    56281 atttatatca actgcatcat acatcccagt tccatccata ggtagtctaa ctataacctt
    56341 attattttta accatatcat gggtattaat ctccccatct ataatataag aatttaatcc
    56401 ttctaacata ccattgttat aaccataaat atttgttttt aaaagatagc caccttcatt
    56461 ttgctttgta caaataccat caaaaaaagt ctttatcctg taatcttttt caagaggttt
    56521 aaagaaattt ttccaaaata gttgttcttc tttaatttgc atagctccaa ataaatatct
    56581 tactggatag acttttgata ttccctcaac attgtttaat cttgaaattt tatcttttgg
    56641 tatacctaca tcaaaatctg ttgtttgcat agttatttgg tagtcagaat ttaaaccatc
    56701 atcagctttc attgtaagtt cattgttatt tttagtaagc tgtatagagt aactagaaca
    56761 tagaaatata attccaccaa gtgataatga aaacaaaatt ccaataaaca ttcccttttt
    56821 ttgagtcatg tatttatgag ataatacttt tgtcatgtta gagtgtttta cactttctaa
    56881 tattctcttt ttcttattag taatcttaaa gtttttcata gattctatac tagagtattt
    56941 attcaactga tgtacaacac gtacagcaat taaaattaac aacaataaga taaataaaaa
    57001 gcctaaataa atagattttt cacttataaa aaatgctcct ggaacaatat cactactcaa
    57061 aaatatatgt ggaaattgtt catatattgt agatgctact ccaataccta agaagcaacc
    57121 tataggaaat ccaacaataa aaagtaaaaa taactctaaa aatagtagaa ataaaagttg
    57181 tttattatta gcgcctaata cttctaaaac cccatattgt gatattctct gaagtattga
    57241 aacatggaaa atactatata ctgctgctgc accaaacact ccaacaagca atataattgc
    57301 atttgtattt agttctaaat tttttaagaa ctcaaatata ttatattttt ctatattttt
    57361 tggtggtttt actccaaatt caactgaaag aggccagttt atataagttt tttcttttga
    57421 tatgttgaat tttttcataa atttataatt ttgcttttta atatttttat tttcatcata
    57481 ttttacataa actatataag aatccttttc tttaggctga aaataatcgt ttacaaatcc
    57541 ctccatagca gtttctgggt ttgaaagact tgataaaata ccacataact tatagatttt
    57601 accatctaaa ttgatttctg ttccaatttc tttgtttaca tttaaattgt ttagagaata
    57661 tgtgtcaagt actatctctc catctttact aggaagagtt ccttttaata attttctacc
    57721 tgtcatgtct aaatatgaag aatcagcatt taaaaattct ataataaaag gttcatctat
    57781 ctgattttta ggttttgtaa cgccaagtct atctacagtg tattcctttg attttttatt
    57841 ttttttaatt ttattaagtt gttccttatc tactttatag aaataatgat aatctccact
    57901 atcttccctt atcttttcaa ttctactttt gtctgcacta tgaactaaag aaccaattcc
    57961 cgtcaataat gctactgata gtactatgct taaaactata gatatagatt gttttttata
    58021 atgctttata tattgaattg aaaattttac tagagacatc atagtaattc accaccagta
    58081 ttcaccacaa ctccatcttc aatatggata attgagtcgc atacttgtgc tatattttca
    58141 ttgtgtgtta ccataagtat cgtttgatgg aattttgcac tactttcttt taataaacat
    58201 accacttcca ttgtagtttt actatcgaga tttcctgttg gttcatctgc taatataagt
    58261 gcaggtttat ttgccaaagc tctagcaatt gctaccctct gttgttgacc accagatagt
    58321 tcgcttggaa attttaaacg cttatcccaa attcccaatg tcttcatcag catttcaata
    58381 tattcatggt ctatatggtt tcctttatct aatgtaacag gaagagctat attatcataa
    58441 gtgtttaata cgggcattaa actgtagttt tgaaatataa atcctatatt tcttcttcta
    58501 aatactgtca aatctttttt tcctatttta gatatgttct ttcctttaat tattacatca
    58561 cctgaggttg gattatctaa tccacctata atatttaaca atgtgctttt tccagaacca
    58621 gaagttccaa ctatagcagt aaatgtatct cgttcaattt ctatacttac tccatttaag
    58681 gcttttactt tagtctcacc ttttccatag tgttttacta aattattcgt cactaatata
    58741 ctcatttaat ttctcctttc aatacagata tatgttctat aaaatattgt aagtgacgat
    58801 aattacactc atcctacaaa attagtttaa actcttacaa ttctgtaaga agatactaaa
    58861 acaacatcca cttcctagtt tagattctac tataatgttt ccattttctt tttctaaaat
    58921 taatcttgta agatatagac caatccctgt gccattttgg ttttccacat ttttacttct
    58981 gtaaaatctt ttaaaaatat catttagttc tctactatca atacctattc cctcatcttt
    59041 aatagtaatc ttcgtatata gttccatttt tattacagaa atagtaatcg tgctatctga
    59101 tggtgagtat tttattgcat tttctaaaac atttacaatt gcttctatgg tccacttttt
    59161 attatgaact aactttatgt ctgaaaatgg ttcgagattt atccttatat ttttagcttc
    59221 tgctttatta aagatagtac tgatactttg aataagagta tctttaatta gtagttcttc
    59281 tacttcaaat tctataactc catcctctaa tttagtcatt ttaaataagg attgtaacaa
    59341 ccagtcaatc ttaaaagttt catttttcat cttttgtaaa aactccttct tctgtaatgt
    59401 ggaaatattt atattctcca gaagttcaca ataaatggtt atatttgaaa gtggagtttt
    59461 taattgatgt gacatatttg atattaaacc tttaatagct tctttttctg actttgactg
    59521 ttctacctct atttctatca tatccttaat tttttttact tggtgagaaa tttttgacgc
    59581 tcttgtatcc ttcgtatctg gataagtaac ttctttacct tccaatattt gatttagcat
    59641 caaatttaat tcatcatatc ttctttgatt tattttagta gatactataa atataacaac
    59701 tgtacatatt ataaaggcta atataaacat attattctac ctcattccat aaataaccca
    59761 ttccataagc tgtttttata tattttggat tagatgggtc atcctctact tttactctaa
    59821 gtcttcttat atttacagat acaatattat catcaacata attttcttcg ctgtcccaaa
    59881 tatggtgtaa aatttgttcc tttaataata tttgaccttt attttcgatt agataactta
    59941 gaagcttata ttctacagag ctaagttcca aacattcttt atttttatat acttttagta
    60001 acttttggtc caattttatt ccattggaat atattacttt attattcgat ttttttctta
    60061 ttgctacttt gactcttgcc tttaatacag ataaagaaaa tggttttgta atataatcat
    60121 caagccctat ttctaatcct tttacttcat caatttctga gtctcttgca gtaagcatta
    60181 taattggtat atctgacttt tcccttatta tttgacatac atcaaatcca tctccatctg
    60241 gaagattgca gtctaagatt ataaaatcta tatttttact attaaatata tttaatcctt
    60301 cttgttttgt ataagcctta aatacattaa atccatcatt ctcaaatgca taaaaaagac
    60361 cttcatttaa gtttatatca tcttcaataa ttaataagtt caattttact ctcctttaga
    60421 ttttttagat aaataattat tttcttgcat tatcatacta aaaatatttt aattttattt
    60481 atttcactaa aaagattgta tttaaatttg ttttcaaaat aaaaacatca taatcaagca
    60541 tatagttata tatttcccaa tttaattacg cttaaattga aaatataact ttattcttat
    60601 ataattaaat tatacaacaa taaagttata ttttttaaat atatttttac tagggggaat
    60661 agaattgaaa agggttgatg agagaaatac tatgtttgca agagcaaatt acaaaaaaga
    60721 tagtactgct tataatgact attataagaa aaatcctgac aaaaaagaaa ttgatgatag
    60781 tataagaaat agaccaaatt tatgtagtga aggaacaatg acttacaatg agttaaactc
    60841 tccaatggca agtagtgcat tcgatttttt atctgatatc aaatctttat gcgaaggaaa
    60901 agtttctgat actaaagtag atgtagatgc aaagtcaatg acaaaaaaaa ttaagggtct
    60961 tgcaaagcag tatggagctt ctgtagttgg tataactaaa ttaaaagact atcatattta
    61021 tacaaatagg ggtagacatg aagaaaatta cggtgaagaa attaatctaa ctcataagta
    61081 tgcaattgta tttggatgtg agatggataa agaaatgata aatagagctc caatgatatg
    61141 tgaagttata gaaacatcaa agtgctatgt ggatgcatct atcgtcggca tgattttaag
    61201 ttactatata agaaatttag gatatgatgc tagaaatcat atggatgcta attatttggt
    61261 aatgcctgtt tttatagctc gtgatgctgg tttaggagat ataggaagaa atgctatact
    61321 tacgaataaa gattatggct ctagacttag attaggtgtt gttactacag atattcctct
    61381 tttagaagat gaatatgttg attttggact agaagatttt tgtaaggtct gtaaaaaatg
    61441 ctcttttaac tgcccttctc attcgctttc taatgatatt aaaattggtg atgatggaaa
    61501 atataattgg gtaattgaac atgagacatg ctatattaaa tggagatatt taggtacaga
    61561 ttgtggtatg tgtatatctg cttgcccatt tagccaaaat ctcgaaacta taaagaatac
    61621 tacttcattt aagggtaata atgagcttat tcaaaaagct ttagatgagt atacttcaaa
    61681 atttggtaaa agaatattta tacctggaaa tccatcttgg ttgaaataat tttatttaat
    61741 aaagaatctg tactagaatt tatcatagga caggttcttt attaaatata taaattttta
    61801 aatacttttt ctcgtttata acaattcagc aatgttttta gtctataatt gacattataa
    61861 aatattaaac taaaaggagt aactgtatgg aaaaaatatt agtagtagaa gatgattcta
    61921 tattaaataa aactctatca tataacctaa ttgaagatgg atatataatt acttcaaaat
    61981 ttacagctaa atctgcactg aagtctattt ttgaatgtga atttgattta ataattttgg
    62041 atattaattt accagataaa agtgggtttg aattatgtaa tgaaataaag gaaaattaca
    62101 atataccaat aattttttta actgctaatg atatggaatg tgatatgatt aaaggctatg
    62161 aacttggagc tttggattat ataacaaaac catttaatat caatatattt aaacagaaag
    62221 ttaaagcttt tttaaatcat cttacaataa aaacaaaaca agattactat agggatggat
    62281 atcttgaaat taacttttct gagttatctg ccaatataaa tggaaatcaa attatattta
    62341 caccattaga atatcgtact ttaaaactgc ttactgaaaa tcctaaaagt attttaacaa
    62401 ggaaagtact tttagaaaaa ctctgggata tagatgctaa ctttgtagat gaacatactt
    62461 taacatctgt tataagtagg attagaagca aaattgaaaa agacaatctt aagtatatca
    62521 aaacggtata tggtatggga tatatgtggt taggtgaaag aaatgaattt taaaaaattt
    62581 tcttttagtt ctatttattt aataattgct gttggtataa tttttacagt tattttattt
    62641 agtatctcaa tttatctaat aactgatgat ttaaaactaa ttgctctatt attaatatat
    62701 acaatagtac tttgtggatt tatagcatta ataatatttt tacttcataa aaaaatagtt
    62761 atattttgtt ataaaatatg tcacacttta gatagtatga tgaatagtga agataatatt
    62821 gaaattgaat tagaagaaga aactatttta tcacgtatca atcacagatt aattagaatg
    62881 tatgaagtta ttcaagaaaa tcgcaatagt attgctatag agaaagctga tttacaagaa
    62941 ctagtttctg atatatctca tcaaattaaa actcctattg caaatttaaa aatgattaat
    63001 actactctac taaatcaaac atttaaaaca gaaattcaaa aggatttttt aatggatatg
    63061 gaaaaccaat tagataaatt agatttttta atgcaatcta tggtaaaaac ctccagacta
    63121 gagacaggta taatcacact atctaaaaag aaaaattcaa tttatgaaac aattgctaca
    63181 gcacttagtg gaattttgtt tgatgctgaa aaaaagaata ttgaagttac agttgattgt
    63241 gacccaaatt tatatataat tcatgacaag aaatggactt ctgaagctat ttttaatata
    63301 ttagataatg ctgtaaaata cacaaattct aatggtaaga tacgtgtagc tacagaatgt
    63361 tgggttatgt atacaaaaat agatattatt gataatggaa aaggaatatc agaaagtcgc
    63421 caagcagaaa tctttaaaag attttatcgt gaagaagatg tccatgacat agaaggtatt
    63481 ggaataggtc tctatctttc aagaaaaatt atatctcttc aaggtggcta tattaaagtt
    63541 acatcagata ttggaaaagg ttcgactttt tctattttct tacctaataa ataaattttt
    63601 aaatatttca tttgtaatga ttctgcaaca ttttggtttt atactgtatt tacaagatgt
    63661 taaggaggta ttattatgag tattttacaa gtaattaatt taaagaaata ttatggacaa
    63721 agttcaaaca ttacaaaagc tcttgatggt gtaactctat ctattgaaaa aggcgaattt
    63781 atttctattg taggtacatc tggtagtggc aaatccacat tattaaatat gatgggagga
    63841 ttagataatc ctacatctgg aaaggttatt ataaagggta aggaattatc tactatgact
    63901 gatgaacagc ttacaatctt tagacgcaga aatataggtt ttatatttca aaattataat
    63961 cttgttcctt tacttaatgt atatgaaaat attatcttac caataggatt ggatggagag
    64021 accatagata aggattttat aaatgaaatt ataaatatgc tttctcttga agaaaaatta
    64081 tatgatatgc caagtaatct ttctggtggt caacagcaac gtgttgctat agctagagca
    64141 cttgtaacaa aaccagctat tatactagct gatgaaccaa caggtaacct tgatagtaga
    64201 actagttcag atgtactgag tttacttaaa gtgacaagta aaaaattcaa ccaaacaatt
    64261 gtaatgatta cacacaataa tgaaattgca caactaactg atagaattat tcgtattgaa
    64321 gatggaaaaa ttgttaacta ggaggtgtag tatatgttta gaaataataa tcgcacattt
    64381 ataagaaaaa tagctttaaa tgatttaaaa attaataaac ttaaaacata tctttcaggt
    64441 atcattataa tgatttctac atgtttatta ttaacagtga ccttagtttc atataatgcc
    64501 tctgtagatt tagttaatgc atctccatat catgctatat ataaatctgt agatgaaaaa
    64561 gcaaaaaata tactatataa aaataaaaac tttagtggcg taggaactta caaattaatt
    64621 ggaagtaata aaaagacaga ttgtattatg tcgattgttt atgcagatga tacagcaatt
    64681 aaacttatga attttcaacc attgaaaggc aaactaccta caaataaaaa tgaaattgct
    64741 atttcagaaa aatatttaca ggaatttggt ttagataaag atattggaga tagcattaaa
    64801 ttaaattatt atgatgatat tacgaataaa gaagttcaat gtgattttat tattgttgga
    64861 tttctagaaa attattatca agataatgcc aagcaatact atacagtcgt ttcaaatgat
    64921 tattttaaga atatagcttc tacaccttta caaaataaaa gtaatacttt tgacgagtca
    64981 agacctgata ctgtagatgt attagttaaa ctatcagaag aaaatacaga gaaagattca
    65041 gcttcaatta agacacagtt aaagaaaatt ggtttatctt taggtattaa gaaatataat
    65101 atatacttaa atgataacta tattgaatca aatttaattg atggtgagca gattattaca
    65161 gttttagtag ttggaatagt tgttcttttt tctagcgttt ttgttatata tagtattttt
    65221 tatatttcag ttgttaattc agttcagatg tatgctaagt tgaaatcgtt aggtatgact
    65281 tcttttcagt taaaaaagat tatttctcta caaggaaata ttttgtcaat tatttttatt
    65341 ccattagggg ttatagcttc ttgtataatt gcttacataa ttcaaccatt agcatggcaa
    65401 atgatagctg atttatttat aattttaatt ttatcactgg taatgttttt aactgttaga
    65461 atttctttat ttaaaccagc tagaattatt tctaaaatat ctgctattga agccatgcaa
    65521 tatacagaaa ctaaatttag aaaaaaagta aaaaatttta gttatataaa tataaaaaat
    65581 ctagcattaa agaatatcga gtcaaataga aagaaaaatt tgattgcatt aatatcgcta
    65641 agcattagtg gagttttatt tatttcaatc gctaatcttg ctaattcaat agatttcaaa
    65701 aaacaactat ctcaacaatt tgtctataac gaagattata taattagcat taagagtgat
    65761 aacttgtatg agcatattac agaaatacaa caaaataatc cactaacaga ttctcttaag
    65821 aatgaaatta aatctattca tggagtaaaa aaattaattg aatccaaatc aattaaaagt
    65881 aatattatag aaccttacat caaagataga gacgaaaaac aatttattac tctaattaaa
    65941 ggtattacgc ctgaactttc aaaatcactt gaagaatata ttgtcagtgg aaaaatagac
    66001 tatacacatt tagattcaga tagtttaatt ataaataaat atagaacaaa atcttatgga
    66061 ttaaatttaa aagttggaga tacagttaca tttaatatct ttagtggaaa tgatattatt
    66121 aaaaagaaaa tgaaaattat aggaatcatt gacaattcca atacaggagg tatgtttttt
    66181 gcttcaaaca aaactttaga atctctaaca ccatataata caaatttaga tttttctatt
    66241 ttaatagata aaaagcattc taaagaagtt gaagaaaagt tgttaagtat aattcagaaa
    66301 aattcaaatt taatgcttta ttcatatgaa gatgattata gaatgattac tagagcattt
    66361 caatatataa ttatagcttc atacattttt gttggtttaa tttcttgctt tggtatacta
    66421 aatatgacca ataccctaat aaacagcgtt ttaattagaa aaaaagagtt tgccttactt
    66481 caagccgttg gaatgacaag aaagcaactg cgaaatatgc tttatagaga aggtttaaac
    66541 ataagtatca aagctatatg tacttcaagt atactaggtt attttggttc aaatctactt
    66601 tgcactttta taaaaaatgt aattagatta gactttatta attttaaatt ttctatattt
    66661 actattttaa ttttttcatt cgtattaatt ggtatacaag ttttagtgac tgaattactt
    66721 gtaagaaata tagaaaaaaa atcacttaca gaacgcttac gttctcagta agaatgtata
    66781 taaaaaatag ccatttttta tacaagtttt aacataattt tttaaaagct aaaaggatag
    66841 aaaattttga ctttacataa ttttctatcc ctatacttgt ttttatttta tacagataca
    66901 cttccttata tctccgagca acattaccag agacataaac aagcatattc cttattttct
    66961 aaatatgtca attgcatgac ttgtaacccc tactaaatct tcacgttcac aagtagcaag
    67021 gtgatatttt aaatataatg caaatgcatc atcatccata gagtctactg cttcacgcat
    67081 atataaagcc aaaccatctg atgcgacata atgcagtcta gttacattaa atgcagacat
    67141 caaatcatca atgttttctt tacgtacaag ctcaaacaaa tcctttggtt cagacttagc
    67201 agcaaatgtc tgtggatcaa tcaaaccttt ttcaatatat tcagatacat taatatttcc
    67261 tctatggaac ccctcgtcaa tgagacagcc atcagatata acatatgcag caaaaaccac
    67321 accaccaggt tttgttacac gaattgcctc atgtaaagct tgttgtttat cttctttgtt
    67381 ataaagatga tatagtggtc ctaacagtaa cgtaatatca tatttattat ctgggaaaac
    67441 agataaatcc atagcattac cctgagtaat gcttatattt tcatttgatt gagtattttt
    67501 atggaaaacc tctatattat gttcgactaa ttccactgcg tcaacatcat atccctgacg
    67561 tgccagtgtg tgagaataac gaccagttgc agcgccaatt tcaagcacac aatcacctga
    67621 ttttatgtac ttatcaatgt aatgcatagt agtgagaaat tccaccattc catgttttaa
    67681 tgcaagtcga ctatcttcat cataagtatt ataaaagtca attaagtatt gttttgtttc
    67741 cataatttca cctcttctat attagttaat aaacatcaaa tagacaaatt ccaatctgat
    67801 ttttcttgtc ttataaaagc tgttaatata tttttcaaca ttttttcagc actatatcta
    67861 tctaatgtta atttttttgt tgctgttaag acagctatgc catgagtata aagaaataaa
    67921 tctaaaaata ttacttttgc acattccaaa tctattccaa tgctttccga aaaaagtctt
    67981 gccttttttt cattgtcaat ttctttataa aaatcattcg cctctttcat catcaaatct
    68041 aaatcattta taaataacaa cttaaataaa tacgtttctt cttgagcaaa ttcaatgtat
    68101 gaaagcggaa gcagtaaata agggcttaca cttttagaat tacgataatt aacaacatac
    68161 tgattataat attcatatgc aaaagcaaga aattcatttt ttaattcatt catgttttca
    68221 taacaagtaa aaattggtcg agtggaacac tgtaatttac ttgcaatact cctcgcattt
    68281 acagcttcaa atcccacttc tcttgtaata tccaagactg tattcaaaat catttctttt
    68341 gttatcttta ctttaggtgg catatatgtt cacctctcca ttaaattttt ataaaacaca
    68401 tgtgttgtat aactatagta acatatcaag aaattatgtc aagaaaaagc tttgcatttt
    68461 tttgcaattc ctaaaactta taaataaaac atgagttgca attaatctat taatagataa
    68521 cagcaactca gattttcctt taaatactct tctttttgtc taatatttca tatacacaat
    68581 cttctattga attaatatct ttttcttttc tttttttaga atcaattaaa atgaaataca
    68641 gtataaaacc tacagcaagt ccccatgttc cgcctttagc agcaattaca cctcccataa
    68701 gtccaatcaa tcccttctca acacctgtat tacatagctc cattgatagc tttgtacata
    68761 aatatccttg aactaaaagt gttactgaca atgctaatgg tataagaggt gtagcaatct
    68821 gcgcaattgg ataaaaacag ataaaaattg ctgaaaccca tactaatgta cccatgccac
    68881 taaaaacaga ctgcatggct tcctttccaa ccttgtacct ttgagcaaca cttcctgtaa
    68941 gtgtcgcagc taatggaccg cacattggta tatatggaga aaagattgcc ataaaaatat
    69001 ttcttatccc acttataaca ttagacctat ttgaattgaa atctatatat tcatcttttc
    69061 tattttcact ttcagaaagt actaagtttt cacctgttat aaaatcacca aaggcaatta
    69121 tgtatatcat aaaagccatt ggtatccctt gtataaataa cattacactt ggaaaaccta
    69181 ttccaaaagg agatactgta tttatcagat ttttaaaatc tactatgtaa actaaattgt
    69241 caaaactaaa tctaggaatt tctatttctt tactaaatat acctactatt aaactcacta
    69301 aaatagctga tactacacca tattctccta aatgaaataa aaatttattc ttaactttta
    69361 gagtatcaaa tctttcagaa aacattacaa aacaagcaac caaaattcct actgttatag
    69421 atataggata agaatcaaat ctccctttag gattaaactc tgatattata gtcgatatac
    69481 cgacacccat tagtattcca cctttaatag aatttggtat cttactaact aactttccag
    69541 ctacaccagt tatacccatt aaaataaata ttattcctaa atctatttgt aaagctgtta
    69601 atgcttgtat tctttcaatg cccatgctga actttaacaa atatgcagtt gtaagagtta
    69661 tagaagctgt aatccagcca ggtacaactg ggtctcccat aaaaacatgc aaacagtata
    69721 atattgagtt aataatagcc atactccatg ccacttcata gggtaatccc aaaatttgtg
    69781 tactaaggcc aattgtgcct aaacttgtca tacttgatat tataccttga atagcttctg
    69841 gtttctcaaa tctgtaatgt ataaatggaa ttcttatctt aaacattcca aattttatat
    69901 gaggttgttc ccttctagcg agtctttcca taacttcact ccacctttca ataactctta
    69961 taagtttaca actttataat tgtttataaa ttatcaatgt cattaaaatt agtatataac
    70021 atgcaaatta tataaacaat aaattaaatc tataaaattg atagattttg tgcatatata
    70081 gaaagaccgc ttcattttta gttacttaaa tcacttaata gtagttattt aaatcacttg
    70141 ataaaggttt tttataaaat tcaatagttc tattccatga ttcaaactgt ccttttgaat
    70201 ttccttctac agttccacct gaagaaaaaa tccctccact catactcata cataaagtct
    70261 cctttagagg cataatatat ggaattggta acggatgacc catattattg tatgttaata
    70321 attctacgtt atatggataa ttattttctt caaagatttc taatgccttt aaacaagctt
    70381 cataactatt ccatatgtta tcttcttttc cagcaatcat aagtatatct gctttggaat
    70441 tttctatttt tattctagcc tcttttctat tctctgctct tttaagactt ttcttataag
    70501 tactattaaa tccaaatgga ataccttttg atatattttt tttctgttct tcaaagaata
    70561 tatcattgtc tactttgata tatggaaatg gctctccttt atatgaccat gatgaagtat
    70621 catttccact catcaatcca ttaagagctt ggaaacaata aatgtgaggt tgtgatacta
    70681 caaccttttt aatttgttca tatcttgaag caagtaaaaa ggccaattct ccaccctttg
    70741 atgtcccatg tacaaatatt tctttagtac tggtaatttc attttcacta atccactcaa
    70801 atactttttc aaaatattct aatggaacct cttctaattt atctggtaac ccttctaaag
    70861 caaagtatgc aactgttagt acattgaatc ctctagatgc aagtggagct gctaaaaggt
    70921 ctagagcgtc taaatttcca tcagaaccac ctagcattaa aattgtttta ttattagaat
    70981 tttgtttata aaataatttt cctataaact catcagatat gtattttgtg gtaatatctt
    71041 ctgatttaaa tattctcttt aattcaactt cttttctttc aatagaagtt tcaaatatca
    71101 tattcataat tattggttta tcaatagata tattttctgc aaaattttta ccttcagttt
    71161 tagatttttc cagcgaataa attaacccca tacaattatc agccttataa gtaccttcta
    71221 taggttcaac taaatctaaa tctacttctc ctttttcatt tgaacaaaac actccataag
    71281 atgaaaattc ttctcccttg caccatggaa attccatttt cacacttatt ttaagtttag
    71341 tatttggaat taagtccgaa accataatct taagtctttc atccacaaat gattctacat
    71401 tgtatacatt tactttcata atctatttct ccttataata attatttatg ttttatataa
    71461 aacagcttta tctaatacaa cataaataaa tttttaaatt aagacactat attgactatt
    71521 tcattttatc aacatattct atttttgtca atatattgtc ttttttagta atttaaaatt
    71581 atgtagtcta tatgaaatcc agttgatttt tggctaatta aagataggaa tcctattagg
    71641 tttagaatat atatattcaa aataaaaaac cactcatttt aagaatggtt tttaatataa
    71701 actatttgtt attaataagg atattttttt atttaaattt atataatcga acatctaata
    71761 tttaatgttt aataaaatta tgcatttgca aaagtatata tggcattaac tcttgctaca
    71821 tataaattct catcactaca tccaatatat ctagcatatt tttcaatctt ttcttttgca
    71881 ttttcaacat cattttcatc gctctccatt aactcattta tataaatatc cattaatgat
    71941 gctttatatt ctcttatatc atagcctaaa aattcagtca atctctcaat ttccttacta
    72001 aaatctccat cttcttttac caaaaattcg tatacatctt ccctatatgg atttaaagtt
    72061 attatttgtt ttactacttt gcattcgtca gccttcccaa taaaaccatc tttataatta
    72121 ttaaataagg cattagattt ttttatagat tcttcatcaa tataagaatg taccgcagtt
    72181 atacgatttt ctataagggc atctacaaca gcataatgaa ttttaaaaca atcattgtat
    72241 aaataattgc tcattttctt tattgtcgat tctatttcta agaagctagc gtgaccattt
    72301 tttttatttt tatttggtat aataaaagtt ttattcaaat tattaaaaag tctcttaaaa
    72361 tctaaatatt tttcacaata aacactttta aaggtatcga tatctatagt tataattcca
    72421 aaacttacta tagtctcaat tcctttctta aaagactctt ctatatattt ttctcctaaa
    72481 cttaaacctc tatcagatat ttgctttaga ttttgaaaac tatttaaaca atctctctca
    72541 aagtttttag atatttctaa agcatataat ttaaagattt tccttatctt attataatta
    72601 ttttttgtat catcaaatct gataatagct ccatttacat caaaagtaat cattgagttt
    72661 taacctcccc attagtttca tcaataaaat aaatttaata taaactttat aatcataata
    72721 ttaaacttat ttatactata attattaatt tgatgataaa agctattttc cttctaaata
    72781 aaaaatttgt ctaaagtttc taaaaaattt agacaaatct taggttatta ctctttaaat
    72841 tatttttaaa ttattccaaa tacgccaaat aatattggta taaatatagc tggtaacaaa
    72901 ttggctactt ttatattcgt taatttaagt acatttagac caagtcctat aattaataaa
    72961 cttccagctg ctgtcatttc tgtgactaca ggatcactta aaaatccatt taaaaatgat
    73021 gctcccacac atataatacc ttcatacaaa aatacagata ttgcagaaaa cattacacct
    73081 atacctaaag aagcagtaaa tataattgaa gctattccat ctataacaga ttttacaaat
    73141 aaagtatcat gacttcctgt aagaccactt tctaatgaac caactactgc catggctcct
    73201 atacagaata ataaactaga tgatataaaa ccctctgcta tagaatcttt tttatttcct
    73261 ttagaaaatt tactttgtaa aaaagcaccc aacttattta cccatttgtc aatatctatt
    73321 aattctccta tcagagcacc tacagctacg gatattattg tcactaatgt gttttttcct
    73381 tctagtgctc ctgatatacc aatgtacaat acacataaag caattccatt cattatagta
    73441 tcgcttactc tttgaggtaa tcctcctttt attataagac ctactataca tccacctgca
    73501 attgctagac tatttgctat tactccaaac attttttctc ccctcgatta gctaattgaa
    73561 atttatccta ttattaaaac ctaaacatct atactttgta ttggatattt taaatattcc
    73621 aaaaattctt caaaaccttt tctagatata tttacagttt tagtatttat gttaggatga
    73681 aaatttaagt aatcttcttt aattacatct ttatctatgt aaagctcaac ttttctttct
    73741 gtatcattta ttaatgaaaa aggatttaca cttccaggaa gaagtttaag tacattgtat
    73801 agtctttcag gtgaagcaaa cgataatcta gaacttccta tcttatcttt aagtgagttt
    73861 aaatcaactt gtttttctcc tttaactaca ataagataat acttatttcc tttggcattt
    73921 cttaaaaata aatttttaca ttgacacccc tttgttattc catctaaaat gactaattgc
    73981 tctgctgtat atacagcttc atgctctact acatcatatt caacatttaa tttatccaaa
    74041 atatcatata ttttagtttc attcatgcta gattcatttt catcttgttc ttttttatta
    74101 tttaaatcac tcatactttt ctccttaaac acttcatcat aatatcattg tgaggtatta
    74161 ttctactata gctattgctc ttactggagc tccatcagca tcattatact taaatggtgc
    74221 tgctataaat agaaattttt ctggaacatt ttctaaattt gtaagatttt ctatgattat
    74281 ttttcctttt tcaaataaaa tatgatgcac ttcaaatact gatgtgtcat atctatccac
    74341 tgatagcata tctattccta tgccttttat attagtatta gctatatagt ttgcagcttc
    74401 ttttgttaat gtaggataac ctacatagta ctgcttttta tcccaaaatt ttgaccaacc
    74461 tgatttaaat attataaaat cactattttt ta
//
LOCUS       DAEORM030000016        71649 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.016, whole genome shotgun sequence.
ACCESSION   DAEORM030000016 DAEORM030000000
VERSION     DAEORM030000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 71649)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 71649)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 71649)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..71649
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.016"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            complement(479..2083)
                     /locus_tag="KRH23_001460"
     CDS             complement(479..2083)
                     /locus_tag="KRH23_001460"
                     /EC_number="3.5.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HHS5224743.1"
                     /translation="MKAKIYYNGNIITMEDSICGDAILIKDKIIKKIGTKEEVFALKN
                     KDTEIIDLQGKTLMPSFIDSHSHLIAFATTLKLVPLEDATSFKDIVKKIQDFKESNNI
                     KKGDWIIGFSYDNNFLEENKHPDKSVLDSASSENPILISHASGHMGVANTLGLKQLGV
                     TNETRDPEGGHIGRVEGSEEPNGYLEENAFFNVASKIKQPSSNEIFNSIEKAQNIYLS
                     YGITTAQEGLMEENQFNILKAMANQNKLKMDVVGYVNLKKSKSVVDNNREFIKKYINR
                     FKIGGYKIFLDGSPQGKTAWLSRPYENSDNGYCGYPIYKDEEVEKFIDISLKEKMQLL
                     THCNGDAAADQLIDAFEKVLNLKEQSSENHIRPVMIHAQTVRADQIDDMKVINMIPSY
                     FVAHTYYWGDIHIKNLGEDRAFKISPLKTTIEKGLIYTLHQDTPVIAPNMLETVWCAV
                     NRITKKGIQIGENEKISPLDALKGVTINAAYQYFEEDKKGSIKEGKLANLIILDENPL
                     TIDPMKIKDIKVLQTIREGEVLYSLK"
     gene            2469..3395
                     /locus_tag="KRH23_001461"
     CDS             2469..3395
                     /locus_tag="KRH23_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-nitrogen hydrolase family protein"
                     /protein_id="HHS5224744.1"
                     /translation="MSKENKNVRIAVVQASPVIMDLEKTVEKALGLIKEAGRKGANIV
                     VFPEAFIPAYPRGLSFGFVVGSRTMEGREDWKRYYDNSVPVPSATTDLLGKAAQEAGV
                     YLSMGITERDGNDINCTLYCTNLFFSPEGKLIGKHRKLKPTGTERCIWGEGDGSTLTV
                     VDTPYGKMGSLICWENYMPLARTALYAKGVKLYIAPTADSREEWQATMKHIALEGRCF
                     VIGCNQYVEKNMYPTDLNYYKELDAEPEIMCPGGSCIVDPFGKYVAGPIFNKEEMLIA
                     DLDLEKIVLSRLDFDSEGHYSRPDVFELIVHE"
     gene            complement(3515..4513)
                     /locus_tag="KRH23_001462"
     CDS             complement(3515..4513)
                     /locus_tag="KRH23_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhdH/YhfP family quinone oxidoreductase"
                     /protein_id="HHS5224745.1"
                     /translation="MNKKFKSLYITEEEGNFRRNIVEREVDTLPEGEVLIKVKYSSLN
                     YKDALSANGNKGVTRKYPHTPGIDASGIVESSSCDDFKIGEEVLVTGYDLGMNTSGGF
                     SEYIRVPSSWVVKLPKNLSLKEAMDYGTAGFTAALSVYKFIDSVDKNMGDVLVTGGTG
                     GVAVIATKILIKLGYSVVVSTGKLEEQKEVLLNLGVKDVIHRSEVDDNSGRPLLRPRW
                     AGVIDTVGGNTLATAIKTTNYCGAVTTCGNAGGVDFTSSVYPFILKGITLYGIDSVDC
                     PMNLRLKIWDLLSNEWKLDDLDDMVNVVSLEELNDSIDSIMAGKHVGRTVVDLEKI"
     gene            4617..5054
                     /locus_tag="KRH23_001463"
     CDS             4617..5054
                     /locus_tag="KRH23_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HHS5224746.1"
                     /translation="MEDKYIVHFISKTKASMIKFIENKLSKNGLGELIPTHGNILTAL
                     YENNGILTMKEIAAKIGKDKSTVTVLVNKLINLGYLERQKCTNDKRITYIKLTKKALL
                     IEDTFNSISTQVKETAYHNITENEKQEFLRILKKINDNFKNAD"
     gene            5140..5727
                     /gene="rbr"
                     /locus_tag="KRH23_001464"
     CDS             5140..5727
                     /gene="rbr"
                     /locus_tag="KRH23_001464"
                     /EC_number="1.11.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0016692 - NADH peroxidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rubrerythrin"
                     /protein_id="HHS5224747.1"
                     /translation="MNLKDSKTKENLLRAFAGESQARNRYNISASVAKKEGLYIIESL
                     FNYTADQEKSHAKQFFSKLKEFAGENISISGAYPVDLYDKTAQHLKAAQHNELQEWDD
                     VYKNFGKTAREEGFESIAKLFENIAEIEKVHGDRFGRYATDLEEGTLFRRNEDIQWIC
                     THCGHIHIGKEAPKACPVCLHPQGYFLDFKNSLFE"
     gene            complement(6027..6647)
                     /locus_tag="KRH23_001465"
     CDS             complement(6027..6647)
                     /locus_tag="KRH23_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhbD family protein"
                     /protein_id="HHS5224748.1"
                     /translation="MEELISKKDLLSKTNISYGQLYRWKRKNIIPEEWFIKKSAFTGQ
                     ETFFPRDKILERIELILSMKEETSLDDIANMFMKKDINKEFDIDFILSKEVICNYTKE
                     IFQNLYKKEQSIGKKELLILSIIEKFLVKSIITFEELKLIVNIIEENFTSIYNESGKI
                     YLFRKFGVPFVVGCLDYKKVKFEKDVVKIIEVDLTKEINDISIKLS"
     gene            complement(6655..7422)
                     /locus_tag="KRH23_001466"
     CDS             complement(6655..7422)
                     /locus_tag="KRH23_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polymer-forming cytoskeletal protein"
                     /protein_id="HHS5224749.1"
                     /translation="MEKGSIKILGEGFISSGEYENIKIVGSSKSKGNVKSNEVKVLGD
                     AKFEGDINIKNFVVNGKTIIRGNLKAERVRVNGQLNIEGDAEIDDLVITAQQKVDGKL
                     KCNNVTIRGQLSVNENMYAQDIKIYGEMRNKSNIECEDIKVYGVIKCDGLLNGENIYV
                     YSGGGSYCKEIGATNIKIGRSKDAFSLIKIINIFSGKFKCNLIEGDTIELEDASIKDI
                     RGKSISLVDNCDVGNIEYSDNLSVSDNSTVKNSIKVG"
     gene            complement(7463..8284)
                     /locus_tag="KRH23_001467"
     CDS             complement(7463..8284)
                     /locus_tag="KRH23_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224750.1"
                     /translation="MNEELSSLRFDGVGKCKGGIFDNVNISGTGKIEGSVKCSKFDSS
                     GSAKVFGTTECNEFFTSGLSKVEGNILASKVEISGLLRCTGNINSVEIDTSGIINVEG
                     SIKSDIIHGEGYLKANENIDCENINLSGILECNGFLNCEEVNISLNGTSNFNEVGASS
                     INIKKGHGDYCKKFRMLEKKHINFEKVSSNLISLGLLSIRKYTESKLFANIIEADEIS
                     LENSEVKVVRGKNIKIGKGCYVESLEYSESIEIDEDSIVGEIKNISEKIKLKKDK"
     gene            complement(8643..10553)
                     /gene="phnW"
                     /locus_tag="KRH23_001468"
     CDS             complement(8643..10553)
                     /gene="phnW"
                     /locus_tag="KRH23_001468"
                     /EC_number="2.6.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047304 - 2-aminoethylphosphonate-pyruvate
                     transaminase activity [Evidence IEA];
                     GO_process: GO:0019700 - organic phosphonate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate--pyruvate transaminase"
                     /protein_id="HHS5224751.1"
                     /translation="MKKIYGEKIKAVVFDWAGTTVDYGCFAPLNVFIEIFKRRGIDVT
                     MEEARKPMGKLKIDHIREMCEMDRIKNLWSDKFGKVPTEDDVNELYAEFEPMLFETLE
                     EYTTPIPHVVETIEKLRENGLKIGSTTGYTREMMNIVEPNAAKKGYSPDFLVTPSEVS
                     QGRPYPWMCYKNAEALGVSPMSSMVKVGDTISDVKEGVNAGMWSVAVIKGSSELGLTQ
                     EEVENMDKEELKSKMSIVSKKFKEAGAHFVIETMAELEDILIKIENETIKSDFVPEND
                     YILLTPGPLSTTKSVRASMLKDWCTWDVEYNNLVQDVRRRLVSLATQNTDKYTSVLMQ
                     GSGTFSVEAIIGSTISKDGKLLVIANGAYGKRMKDICNYLNIQFVDCTFKDIEAVDLN
                     VVENLLKENKDITHISMVHCETTTGRLNPIQEVGKLAKEYNKIYIVDAMSSFGGIEID
                     VEDFNIDFLVSSSNKCIQGVPGFGFIIANKEELSKCKGIAKSLSLDVYAQWETMEKNN
                     GKWRFTSPTHVVRAFYQALLELEEEGSVEKRYARYKENQFTIASRLKSLGFDTLVNDN
                     AQSPVITTFLYPKNAKFEFMEFYTYLKDNGFVIYPGKLTDIDTFRIGSIGEVYPTDME
                     RLADVIEKFINR"
     gene            complement(10831..11616)
                     /locus_tag="KRH23_001469"
     CDS             complement(10831..11616)
                     /locus_tag="KRH23_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HHS5224752.1"
                     /translation="MSLNSIDRKKEILKLLDSKGKVNTKELVKRLEVSSETIRRYLEE
                     LENENKLKKVYGGAIKINYGVIEPEHIKRNNTNLDKKQSIAKYAAKFVNDNESIIIDE
                     GTTNLQIVDYIISVNNLKIITNSYPVLSKLISYENQGLFDGEVIFIGGKVNLKHQRTA
                     CPMSIDTMKNLYVDKAFISSEGILDSFGISSIDQNKALLSKEYIKNSKESFVLCDSSK
                     IGIASMYKIADLEELDFVICDVEPPNEWKDKLNEINITWIEAK"
     gene            complement(11833..12063)
                     /gene="dltC"
                     /locus_tag="KRH23_001470"
     CDS             complement(11833..12063)
                     /gene="dltC"
                     /locus_tag="KRH23_001470"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0036370 - D-alanyl carrier activity
                     [Evidence IEA];
                     GO_process: GO:0019350 - teichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HHS5224753.1"
                     /translation="MQETVIEIFEDVLGTDEIREDLDLNLFETELLDSLAIIEVLLEI
                     ENRLGIELQPTDLERKDMSTVNNLVKFLETRK"
     gene            complement(12082..13230)
                     /gene="dltB"
                     /locus_tag="KRH23_001471"
     CDS             complement(12082..13230)
                     /gene="dltB"
                     /locus_tag="KRH23_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0070395 - lipoteichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HHS5224754.1"
                     /translation="MIFSQYGDYFYLYILLLTSIPAVILGLMGKNIKYYGMLASLFMI
                     FLIVGIDVQLKYLVIFIILEVIIVKGYEYVRRKTKNKYIYWGFLFASMLPIIINKISP
                     VTSFGIIGFIGISYLNFRTIQMVIEIYDGAIKEVKISKMLYFMLFFPTLSSGPIDRSR
                     RFEQDLEKQISRKEYIEEYLLPGIKNIVMGVGYKFVIAFLINTYWVSRIPKDMSFINI
                     LSYMYAYSLYLFFDFAGYSLFAIGTGYIFGIQVPINFDKPFISKDMKEFWTRWHISLS
                     RWFGDYIFSRFVMSSMRKKRFKKRTTAAHVAQMITMITMGFWHGLTWYYVAYGVYQGL
                     ALVLTDIYQRKSKFYKKHKKDKWFERVQIFITFHIVCFGLLIFSGYLA"
     gene            complement(13230..14744)
                     /locus_tag="KRH23_001472"
     CDS             complement(13230..14744)
                     /locus_tag="KRH23_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase"
                     /protein_id="HHS5224755.1"
                     /translation="MKIIEGIKKYSNTDRTALMCNGDKLSYKDLNEYSDAISVFLKDV
                     YKEEDTPIVIYGNKENMIMACMIGALKSGRAYVPLDISFPIDRVFEVTKEIKPKVLFN
                     FSDERNFGDINVIDMDKLNDIINEYQGKSLDKENWVKDDENAYILFTSGSTGKPKGVQ
                     ISSNNLDSFSDWISPYLNIDGSEKVIMNQPAYSFDLSVTTIYPGLIHGATLFSISKDV
                     LADYKELFRQFSISDIAVWVSTPSFAGVCITEKEFNSKMLPNLESMIFIGEALSKNLT
                     KELMSRFPNTRIINGYGPTEATVGVSVNDMTQKAIDDEKSLPVGYPMSNCKIKILDED
                     GNELKENEKGEIIIIGPSVSKGYFNNKEKTDEVFFYDEIDGVKWRAYKTGDMGYLLDG
                     NIYYCGRKDFQIKLNGFRIEIEDIENNLRKVHNVKNAVVLPVYKDEKIAYLKGIVELN
                     EKNDLSNIKNGMIIKKELGKYIPSYMIPRNISIISEFPTNINGKIDRKKLMEEI"
     gene            complement(14865..16055)
                     /gene="dltD"
                     /locus_tag="KRH23_001473"
     CDS             complement(14865..16055)
                     /gene="dltD"
                     /locus_tag="KRH23_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0070394 - lipoteichoic acid metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HHS5224756.1"
                     /translation="MRKLIYFITPFIIGVVFLFGLDKFLDSKTDELLREKNLLPIMDD
                     TLSDIKDKGVTANNHFLREKDIMILGSSELSNSTKQHPKYYFNTNRSKNKVFAIGRAY
                     TQTLQDAAILGSMNPNIDNKKVVLLISMQWFMEKDGVTSHHYQSRFSPIQFYRFLDNP
                     KISKQNKIEYAKKSSKLLWGSDEYKAEALYAKLYEPKTFPEKAEKVLLEPYFQGRKYC
                     IALKEKGILYKRLIKLDKKRATKRKRPINWSYERKKAIEDAKKRVGKNPLNIDKYYYK
                     EHFKDGIEQYKGRDKDVNLLTSKEFENYKLMLNVCTDLGIKPVVVLIPSMDKFYNLTG
                     ISEKERNQYYDKAQKIAESKGFEVLNLKDKGSDKYYLRDVMHLGTKGWVDVCERLFKI
                     FKEQ"
     gene            complement(16343..17362)
                     /locus_tag="KRH23_001474"
     CDS             complement(16343..17362)
                     /locus_tag="KRH23_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family protein"
                     /protein_id="HHS5224757.1"
                     /translation="MMGKIRFGIVGTSNIANIFLRAASRVKDFELVAVYSRNLEKARE
                     FGTLYGASIFFDDLEQMAKSKDIDAVYIASPNALHSKQTITCLKHKKHVLCEKSLASN
                     LKEVKSMIKTAKDNNVLLMEAMRITCVPNFKAVKENLYKIGKIRRFFGSYCQYSSRYD
                     KYKNGIIENAFKKELSNGALMDIGVYCIHPMVNLFGAPKTVKAVSHILQTGVDGEGSA
                     VFQYDDMDAIIQYSKVADSYIPSEIQGEEGSIIIEKLNLFEKAIIKYRDGREEDISIP
                     KEKAEEKPREIEGMYYELVEFISLINNNKIESNINSHENSIIVMEIMDEIRRQSSIVY
                     PADSI"
     gene            complement(17538..18077)
                     /locus_tag="KRH23_001475"
     CDS             complement(17538..18077)
                     /locus_tag="KRH23_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative ABC transporter permease"
                     /protein_id="HHS5224758.1"
                     /translation="MDNVGSLLYFLFNFFLYGFIGWIIENLYSYYKQGHFQEDGFLNG
                     PFKPMYAIAMSIIIEVSRFIDPNNIFALLLLCLVVPTVVEYITGILMKVYFNKVYWDY
                     SDYKYNSRGIVCLKFSVYWTILTFIGVRYFQVYIVDSLYSLIIPYWPIVVTILLVTLF
                     VDEILTIKFLRGNKDIVER"
     gene            complement(18178..18858)
                     /locus_tag="KRH23_001476"
     CDS             complement(18178..18858)
                     /locus_tag="KRH23_001476"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HHS5224759.1"
                     /translation="MQKVEGIIFDMDGVLFDSERISLEFWMETFEKYGYTMTKEIYTS
                     VMGRNRKGIIEGLTDIYDSSVPIIDLYDEKTKNMIEFMERKGAPIKLGVNELISFLKE
                     NGYKMAVATSTKRERAVKRLAKANLKDYFDAIVCGDDVVNSKPNPEIFLKAAKKINVN
                     PQNCIVIEDSPMGVEAAYNGGIRCINVPDLKEPDEQIKSQSHKILENLLEVREYLKSL
                     NSKECHNL"
     gene            complement(18887..20143)
                     /locus_tag="KRH23_001477"
     CDS             complement(18887..20143)
                     /locus_tag="KRH23_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin family protein"
                     /protein_id="HHS5224760.1"
                     /translation="MLVLINAFFVACEFAMVKLRSSRIDTMITEGNNNAKRCKIIKDN
                     LNSYLSACQLGITLCSLALGWMGESTVKELILPIVSVFNLSESIIYTISISISFLIIT
                     MMEVVIGELVPKALALYNTEKIMLSTSFLLVGFYKLTYPIIYFFNLSTDLFLKPFGYS
                     QADEVDEPHTGDEIRLLVEESYKSGLIDESEQRLVDNIFEFEEKKIREIMVPRTDMVC
                     IYESDSEEKILAILKEEGVTRYPVCRKNKDDILGFVHIRDLYNQKINENKIELEEILR
                     DIIYISENLTIDKALERIRKEKLQLAIVVDEYGGTSGVVTIEDILEEIVGEIQDEFDK
                     EETHIKKIGAGSYLVDGTESINYINKYFGLDIEHDGFDSIGGWISYMLGSNIKVNQSV
                     TFENYNFTILELDKLRVVKLIIKSVI"
     gene            complement(20640..22241)
                     /locus_tag="KRH23_001478"
     CDS             complement(20640..22241)
                     /locus_tag="KRH23_001478"
                     /EC_number="3.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047420 - N-acyl-D-amino-acid deacylase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acyl-D-amino-acid deacylase family protein"
                     /protein_id="HHS5224761.1"
                     /translation="MIYDLILKNGFIIDGTGNPGFYGDIAIKDNLIAKIDSKINSNTN
                     KEIDCCGKVITPGFIDPHVHEEIVAILDGKFEKFLKQGVTTTINGNCGHSITPYSSEN
                     VYEYMYKNGLLLEEEKKYLIDKNKCWNNFTEYCDLISKSGISVNMGFLLGHGTIRWSV
                     MGGSKDRPPTEKEKNEITDIINDGMKSGAFGISTGLAYIPSKYADIDELVDIARQIKE
                     YDGIYTSHIRDYIGRYNAVKEAIEVGQKSGARVQVSHLSPVEIEAFDEILKARYNGVE
                     IMVDTVPRSSGHCMKKKRVIQFIMAISSSLFELGINGVMDALRNEEGRTLILKEAFIL
                     GDRGSIILLNTKDINMEKKSIREIATQKGIDEDKLLLDLLLDGDEELIFCLGGMYRAD
                     FPDKLHDDKIIDNPFVMVGSDCLFSVGGDMSWFELQRRGAFPIFFNMYRKSGVRLEEI
                     VRRVTSLPARQFKIKNRGILKEGLIADIAVIDMDNYSYPRSEDIDFSKPQLLANGVEY
                     VIVNGKIALENGEITENKCGEVLKR"
     gene            complement(22352..23029)
                     /locus_tag="KRH23_001479"
     CDS             complement(22352..23029)
                     /locus_tag="KRH23_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224762.1"
                     /translation="MSKVKSIYNEEYLPFMIRYGRLTLSLGIIAALVPGIILSFGFGI
                     MPPISALLASTMAIVSMSAPNYIIEPVSYSPILGIPGTYMSFLSGNISNMRLPCSIAA
                     QKAAEVESGTEEGSIISTIGIAVSILVNISILTIGVILGGSVLSKIPAEVVEKLNLIL
                     PALFGSVFGQVFLQDKKLGLVAIVISVLTIILSKQGIIPQSLVVLICVFGTILIARAM
                     YKDKLSD"
     gene            complement(23042..23737)
                     /locus_tag="KRH23_001480"
     CDS             complement(23042..23737)
                     /locus_tag="KRH23_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5058 family protein"
                     /protein_id="HHS5224763.1"
                     /translation="MDYLKLANHPLLWIASTVAVSIVVVQSLIFAIKSCKVGKTMGIT
                     DKQIKSAVKSSAISAIGPSMTIFAGMVSLIVTMGGPIAWMRLSFIGSVIFESMSAGFG
                     TDALGITLGSPEMTKLAFTNAVWTMILGSLGWIIFTLLFGHKLDKITNVISSGKKSFI
                     PIISLGAMLGSFAYLNADRVLRFDNGTIACISGMAIMVILCMLEKKKNIKWLREWGLT
                     ISMFSGMIIASVI"
     gene            complement(23789..24988)
                     /locus_tag="KRH23_001481"
     CDS             complement(23789..24988)
                     /locus_tag="KRH23_001481"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0070573 - metallodipeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HHS5224764.1"
                     /translation="MKSAYKGYEAYSYLEKGKDISSIEMCKGDKRVKEYLIELDDIQE
                     AKVKSIVDEKIFISLHEHPVLFPEHLERDIFEYNREGKQRCAYEALSRGYYDAIFDNL
                     MDGVCTITSNSGWKWDDILIDLGMRLCDLAHQDFVIKCEKVEDIYRAKSEGKVALIPT
                     LEGAAPIENELDRIDILYGFGIRLMGITYSESNALGSGLKEEKDGGLTNFGKKAVERM
                     NKIGMAIDCSHVGVQTTLDVIEYSKDPIILSHVGARSLWNTKRLTPDEVLIACAKKGG
                     VIGVEAAPHTTITEKNKEHSIESFMEHFEYIKNLVGIDHVAFGPDTVYGDHVKLHSVL
                     AAKFDIKKITGTKEHPKVEYVKGLENPTETSKNIVRYLVKHGYSDEEIEKVLGGNILR
                     VLKQVWK"
     gene            complement(25249..27294)
                     /locus_tag="KRH23_001482"
     CDS             complement(25249..27294)
                     /locus_tag="KRH23_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54 interaction domain-containing protein"
                     /protein_id="HHS5224765.1"
                     /translation="MKKHNILFVSTDDKINIDISKQLENIFGEFCNIDNLVYVNRINI
                     ELSSYELVVCSDNDIKEYIHNNIDKNIPIVIVHRTINIENINQIISIENDSDVMVIDA
                     YKESADETAKIIRKLGLIHINLIPYYPGCDKSKCEIGIITGSRNSIPQNIKQIIDIGD
                     KVIDINTVIEIFTKLNISIDKLHIIKEKYNEDTVSGYRYYTTMNKTMKSFLEIIDEGI
                     ASVDKLGKFIYCNKVFSNLVGIDQNEIISNNFMDLFSDKVVKKIFFQEDEVNDEVVNL
                     NNKKLIINKVNVYENNERIKSIISIKNISAIQVLEDKIQNKLQSKGFVSKYTFESVVG
                     ESKIIKEKINIARKIATTDFSVLILGENGTGKEIFAQAIHNESLRKNKPFVAVNLSSL
                     SDTLIESELFGYDEGSFTGAIKGGKMGIFERAHTGTIFLDEIGDISLDVQQRLLRVLQ
                     EKEVMRMGGSKVIPIDVRIIAATNKDLKKKIKEGSFREDLYYRINVLHIEIPRLRERK
                     EDIPLISKYFLDEINSNKCFTEESMQALTLYEWPGNVRELKNLIYYIDTIVEEDRVDY
                     EHLPEQFRFEKNNTLVNENFDSIILDFKQSNFFEESICILTSIETWNNKNILLGRNKL
                     QEILKEKDIVLSVDQIRKRIDKLKSHGLLLSGVKKQGSFITDEGKNFISYVKIKGVI"
     gene            complement(27705..28514)
                     /locus_tag="KRH23_001483"
     CDS             complement(27705..28514)
                     /locus_tag="KRH23_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HHS5224766.1"
                     /translation="MYYVYVNDINIAVYDLNPSAKKTVLFIHGWPLGHKIFEYQTNIL
                     PKLGYRTVSIDLRGFGKSDATSGGYTYSQLADDIYKVVHAIGLKDFTLVGFSMGGAIV
                     LRYMSLFNGYGVSKLVLAAAAAPSFVQRPPEFPYGMTREDVNKLIAQACTDRPEMVTD
                     FGEKVFASNPPESFRRWFNDIGFSASGIGTIGTAVSLRDEELFNDLKCVRVPTGIFHG
                     KLDEICPYEFAVFMNEKIEDSILYTFEYSGHAIFYDELKLFNQEFLQFLEE"
     gene            complement(28598..29023)
                     /locus_tag="KRH23_001484"
     CDS             complement(28598..29023)
                     /locus_tag="KRH23_001484"
                     /inference="COORDINATES: protein motif:HMM:NF012436.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferritin-like domain-containing protein"
                     /protein_id="HHS5224767.1"
                     /translation="MDDYAGVSSEFTSVNQYLYHNFDLDETHRELSEMWINISITEML
                     HMEILAKTIRLLGGNPVYRGSTSSCGAYWNGGFVCYGNSICNRLKLDLHLEHVAINNY
                     YKDISLIEDPYIKAILNRIILDEKLHVSLFEKAIEKYCK"
     gene            complement(29280..30629)
                     /locus_tag="KRH23_001485"
     CDS             complement(29280..30629)
                     /locus_tag="KRH23_001485"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008237 - metallopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TldD/PmbA family protein"
                     /protein_id="HHS5224768.1"
                     /translation="MELKNFKDILFKKALSEGFEECEIYYYTGENLSINIYEGEVEKY
                     NLDKSFGLSFRGKVNGKIGYSYTEILDDKAVDMLIKNVKDGVNTIENEDVQFIYEGDK
                     HYNDVKTYSKELENLEADKLIDLALEMERETKAYSDKVVNLSKCTISYSVSSNGISNT
                     KGLNLSNKTNMLIGFVVPIIEDNGQKYDGIGYNIANSIEEIKPCEIAKLGVDNALSKV
                     GGKSIPSGKYKTILLNEAMVSLLSTFSGIFNADSAQKGLSLLKNREGDMIASPIVTIV
                     DDPLLENGMASTPFDDEGVATFKKEVVLNGKLITLLHNLKTANKAGVKTTGNGIKSSY
                     SSPISIYPTNFYIEKGDKSLDEIIKDIDEGLMVTSFAGLHSGANSVTGDFSLAAKGFY
                     IKEGKKVFPVEQITVAGNYFDLLKDIEAIGEDLEFPMSSIGSPSVVIKELSVAGKDE"
     gene            complement(30641..32023)
                     /locus_tag="KRH23_001486"
     CDS             complement(30641..32023)
                     /locus_tag="KRH23_001486"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008237 - metallopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TldD/PmbA family protein"
                     /protein_id="HHS5224769.1"
                     /translation="MLSKNIASKVLEKCLITGGDFAEIFEEDTINNSISLIDNKVENA
                     IGGRNYGIGIRIFKGLKSIYAYTSDNSLNSLLDVAYKAAVALGKLEDGKSVILNDSIK
                     INNIHNIKIYPNSIGNRDKVSVMKVTYKSAKEFSNDISQVSVSYLDKDQKILIANTEG
                     IYVEDRRIRTRLGISSIASKGNENQTGFEGPGGCKGFEIFEEIDPEYYAKESARVAHT
                     MLHAKNCPAGNMMVAIDNGFGGVIFHEACGHSLEATSVAKGNSVFADKLGQQIASTKI
                     TAIDDGTIPNYWGSMNIDDEGNPTQKNILIENGILKSYMIDKLNGRRMGMNPTGSSRR
                     QNYKFAPTSRMTNTYIAAGEDKPEDIIKSIPDGLYAKKMGGGSVNPVTGEFNFAVSEG
                     YLIKNGEIQEPVRGASLIGKGSDILMNIDMVGNNVKQAQGMCGSSSGSIPTNVGQPMI
                     RVKEITVGGR"
     gene            32267..33481
                     /locus_tag="KRH23_001487"
     CDS             32267..33481
                     /locus_tag="KRH23_001487"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HHS5224770.1"
                     /translation="MNQEYVKGNPIFTNINKVPRQFPYLTDDIDTDVIIVGGGVTGCI
                     CAYYLAKNNIKSVILEKGRIAHGSTSVTTSLLQYELDDNLIDLTEVMTLKDALKAYNL
                     CTSALEELDTFIELYGNKCDYAKRDTLLYTANKLEVKAIKEEYNLRKENGFDVEYIDE
                     STNPFSFDLKSGLIAKNGGRELDPYKYSHHLIDVSLKNGLQVYENTEVKKVDLSNDKV
                     TAEVSYGYKVHGKKLIVATGYNTSLFTKRNFATKSNTFNIATKPLKNIASWKNNILIR
                     DNCDPYNYLRTTKDNRLIIGGEDVNFDDIENETLANEKYDILEQRLKSMFKDIKDIEV
                     EYKYCGCFASTLDNLGFIGPDNKNNNLWYCLGYGANGILFAILGGIMLSELYLGKQNK
                     NMKLFKVDRFDK"
     gene            33658..35571
                     /locus_tag="KRH23_001488"
     CDS             33658..35571
                     /locus_tag="KRH23_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HHS5224771.1"
                     /translation="MKYGGIIMKEILVIAPTKGTYEKSIHIVKKNKYKNIDVVFGNLK
                     EGIPLAEKSINHGTRIIISRGGTYNMLKATYNIPIVEIKVDAYDIIKSYKEVKNSNEP
                     FGIIGFNNVIYGFDIIEEILNKKITMIEIEKEEEIYDAIEKYRKKGINTYIGDTTVAH
                     IVKRLNCKGILIESREENILRAIQQAEQILEATKDEQKRRLQIEAMTDFVHDGIITVD
                     KNFKITLFNKSAEKIFGIKKENALYHNVVDVIPNTVLPQVVETMEPQIGEIQNIGSTK
                     IITNRVPIIVDGQIQGAVSTFQDSKEISSFEHTIRRSLLSKGLSAKYTFDDIIHASEK
                     TKDCIELAKKYACYDTPMIITGESGVGKELFCQSIHNYGKRKNAPFVAVNCAAIPPSL
                     IESEFFGYEEGSFTGARKKGKAGVFELAHEGTIFLDEISEIPLELQGRLLRVLQEKQV
                     MRIGGDKVIPIDVKIICASNKDLKNMMRNGLFRQDLYFRINILTLYLPSLKERKEDII
                     KLSEFFIHKYSSKYNKTPLIITPNIKKALLEREYEGNIRELEGMMERAVIVESFDSIL
                     LEKVSNEYTNNIVDKDNSDFECSNLDLKTLEKKYIYKIYNENNRNTTKTCEILKITRS
                     TLWRKLKEIEDDV"
     gene            35842..36816
                     /locus_tag="KRH23_001489"
     CDS             35842..36816
                     /locus_tag="KRH23_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-keto-3-deoxygluconate permease"
                     /protein_id="HHS5224772.1"
                     /translation="MHILKSVKKIPGGLMVCPLLLGALFNTVCPQALEIGGFTTSLFK
                     TGAMSILALFCLCNGAQINIRQAGKPLTKGIVLTATKFIIGAVLGIIVSKFIGPKGII
                     GITPLAIVATMTNSNGGLFAALAGEYGDSTDVGAISILSLNDGPFFTMLAFGVTGLAN
                     VPIIALFAALIPILLGFILGNLDEDIREFLAPGTTLLIPFFAFPLGAALNFNQIITAG
                     LPGVVLGLGVTIITGMGGYFVMKLIRAEHPAVGAATGTTAGNAAGTPEALAAIDPTLA
                     TIAAVSTVQVAAAIIVTAICCPMLVSYLDKREKKKKSIFKTNKNIEVN"
     gene            36837..37112
                     /locus_tag="KRH23_001490"
     CDS             36837..37112
                     /locus_tag="KRH23_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HHS5224773.1"
                     /translation="MNAIIHANEKDNLVTCVRPLVKGEKVSIDGKSYIVNDNIPVFHK
                     MATEDVKKGDVVYKYGEIIGIATVDIKTGDYVHVHNIESTRGRGDKK"
     gene            37125..38288
                     /locus_tag="KRH23_001491"
     CDS             37125..38288
                     /locus_tag="KRH23_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HHS5224774.1"
                     /translation="MKLMGYLRENGQFGIRNHVLIIPTSVCSSETATRIASLVPGAIA
                     IPHQHGCCQIGSDIELTAKTLIGFGKNPNVAAVLVVGLGCDGIQAKELASEIATTGKK
                     VDYVVIQECGGTLKTVSKGAEIVSKMAREVSKEVRVEFGMSEITLALECGGSDPTSGI
                     ASNPSIGVASNLLVDEGGSSILSETTEVIGAEHLLATRFEDEEMKDKFLKFVSDVEKR
                     AIAMGEDLRSGQPTPGNKTGGLSTIEEKSLGCMYKAGNKPFKGALEYADIVPPDKKGL
                     YFMDTPGQDIDSITGMVAGGAQIVIFSTGRGTPTGSPISPVIKITGNSDTYNKMPDNI
                     DINAGRIITDGAKIADIGQEIFNEIIEVCNGKHTKAESLGHREFGIYRISSTF"
     gene            38625..40904
                     /locus_tag="KRH23_001492"
     CDS             38625..40904
                     /locus_tag="KRH23_001492"
                     /EC_number="2.7.7.65"
                     /EC_number="3.1.4.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0052621 - diguanylate cyclase activity
                     [Evidence IEA];
                     GO_function: GO:0071111 - cyclic-guanylate-specific
                     phosphodiesterase activity [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="HHS5224775.1"
                     /translation="MNFENTKNKKIIATLLLTLLLIVSLTCVTFIMNLNKVTHNETER
                     YLVEVSQSISTTINVKCKSIFRTLYSMGDTYFEINDSEKEVNRYLSKKLKLFEFDWLG
                     IIDSNGNFVSALKDTGNVKGQDFYRKALQGKETITPVKSQSGTYGILYSVPLYNGDKI
                     VGAVAAWNTIDTMRNLLSVESFHGEGFSQIIDQDGNFIVSSANKNAPKNVVNFFDMIK
                     HQGKQVDKNKLEEMKINLKKNKTGSMYYTLNDGISKAMHYLPLQEENLYLLSVVPTKT
                     ASAQFDLLLKKAIFINILIVILFLLLIILIMFINQKNRAQLIKIAYVDSVTKGYSKAR
                     FDIEAKKIIQSSSSESYSLVSINIQKFKLINDSFGSEAGDKTLKYIHDVISNYLEPGE
                     LLCRVSNDQFNVLIKTIPQKEILKYIENITNDINSFNKNEECKYFIALSIGVYKIDDP
                     NLPLVSIQDRANVARKNNKGNIGNHPLYTCVFYSDLERLKMIKEKEMENRMEEALNNN
                     EFIVYLQPKISLKDNTIVGAEALVRWQDPNKGLIPPDEFIPFFEKNGFITKLDHYVFE
                     KVCSMIRKWIDNGETPIPVSVNFSRANLNNIDFLEKYRMLRNKYNIPAKLLEIELTET
                     LVFENLQKLINIIDQIHEEGFQCSLDDFGSGYSSLNMLKEIKVDTLKLDRAFFSSPNA
                     DNIAENHVIESIVNLAKKLNMNSISEGVETILQMDYLKKINCDMIQGYVFSKPLPQEI
                     FEKMTFGKKLEETSMDSSV"
     gene            complement(40999..42339)
                     /locus_tag="KRH23_001493"
     CDS             complement(40999..42339)
                     /locus_tag="KRH23_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA];
                     GO_function: GO:0042910 - xenobiotic transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006855 - xenobiotic transmembrane
                     transport [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HHS5224776.1"
                     /translation="MENQEALRHEKIWILLFRYSIPAIIAMMVTSLYNVVDRAFIGSM
                     EGIGSIAIAGLGVTMPVFTLIIAFGMLVSVGASTRLSIKLGERNREEAEKILGNALTL
                     SIIISLIITILGLVFLEDILFILGASKDSIFYAKDYMSVILVGSIFNLVAFSLNNAIR
                     AEGNPKLAARTMIVGCVLNLILDPIFIFVFNLGIKGAAIATVLCQIVVFFWVIHYFIR
                     GKSNLKLKKCNLKLNKDIVKKVFTIGMTPFAMEVAISITHMFTNNSLKVYGGDLAIGA
                     MTALTSILLMFMMPVFGLNQGMQTIISYNYGAKQYERAKKTLILSIIVSVVILSFGFL
                     VVQVFPEVFVGIFNKDSDLMDIAVRGISINLITLPIMGISIVGPVYFQCISKVKHSMF
                     LTLLRQFILFIPLIIVLPIQFNLDGVWLAQPVADFIAMIIVLLFLKREFKTSRV"
     gene            complement(42351..43133)
                     /locus_tag="KRH23_001494"
     CDS             complement(42351..43133)
                     /locus_tag="KRH23_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHS5224777.1"
                     /translation="MNCINTKNLNVSYGNTDIIKNLNLNIPKGKITTIIGANGCGKST
                     ILKTIGRIISPNSGKIYINGEDIYKKKSKEIAKDMAVLPQSPQAPSGLTVSELISYGR
                     FPHKSGFGNSSKEDREIVNWSLEVTGIAEFKDRNMEDLSGGQRQRAWIAMALAQETDI
                     LLLDEPTTYLDLAHQLEILKLLDELNKKQGRTIVMVIHELNNAARFADHMIGIKKGKI
                     VCEGDAYDVMTKDNLKELFNIDAEIATDPRTNKPICITYDMV"
     gene            complement(43148..44170)
                     /locus_tag="KRH23_001495"
     CDS             complement(43148..44170)
                     /locus_tag="KRH23_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FecCD family ABC transporter permease"
                     /protein_id="HHS5224778.1"
                     /translation="MKNIIKINSKTLLVISILMVLIFITFLLSLNMGSFSIEPMDVIK
                     TFLGQGQRNHEIAIFKLRLPRIVIALLVGSALSTAGVILQGVTKNDLADSGILGINSG
                     AALFVVVYIYLMNGNVYEGMSNLTVFTMPIVALIGALFGAFLIYSLAWKGGINSSRLL
                     LIGIGVNIAFTSILTIFQLKFTTQEFNRVMAWTSGSIWGTSWKYVIAVLPFIVIFMGI
                     TIYKSKYIDVLNLGDEVSISLGVDLEKQRRRLIIYAVILSGVSTAVAGSISFLGLIAP
                     HIGRKIIGPKHKRLIPVSALIGTLLLLIADTISRNLLAPIEIPVGIVVSIIGVPYFIY
                     LMLVND"
     gene            complement(44176..45189)
                     /locus_tag="KRH23_001496"
     CDS             complement(44176..45189)
                     /locus_tag="KRH23_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FecCD family ABC transporter permease"
                     /protein_id="HHS5224779.1"
                     /translation="MTKLSKKNITYLLILVSIVVLVFGIVLSITIGAKDMNLSTVIDS
                     LIKMEDGINMRIVKDVRLPRAIAAALVGGFLAVSGAIMQGITRNPIAEPSVIGITQGA
                     TFAISISLVLQKKLPQLIHGSFSVMMFAFIGASISGLFIYFISSKSRGRVNNVKLALA
                     GVALGTLLISLASAISMYFNLSQQLSFWISGGLVGVKWEGIKLLFVAGGIGFILAIIM
                     APRITILSLGEEVAIGLGQKTNFVRFICIVLVILMTGASVSVSGNIIFIGLIVPQIAK
                     GIVGSDYKYIIPSSLVLGAVLLVYTDILSRMINPPYETPVGSITALIGVPIFIYLVRK
                     GEK"
     gene            complement(45317..46255)
                     /locus_tag="KRH23_001497"
     CDS             complement(45317..46255)
                     /locus_tag="KRH23_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HHS5224780.1"
                     /translation="MKKIKSLAIFISIITTLVLVTACSDKNTEDKDKSETRVVQSVKG
                     EVKIPSNPKKIVDISGSSEELLLAGYKPVATANVDSYETDKLPSYIREELKGVKIVGH
                     SMMDTMDMEAILEVNPDLIIMSQRQEKIYDQLKEIAPVVMMKDYANDWRSKLTDVSKL
                     FDKEEEAKSWLQKYDEKATKLGKEVIEKNGEKTYLPVLASSGQFMVFSDGGIGTLIND
                     DMKLARPKNMPKQDGITLPMVSMEGLTDIDADHIVVIATETDKKDLENSAIWAQIRAV
                     KDGNVTILDAAPFFSQSYNPIGKELLLESVKNELTK"
     gene            46525..46989
                     /locus_tag="KRH23_001498"
     CDS             46525..46989
                     /locus_tag="KRH23_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016208838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224781.1"
                     /translation="MVHLVYCDNAGKKGEKVLDKILAGTKTMVIRGAAGRKIPHSRVF
                     EDELLYFMEKGTAKISAKATVKKVKNYVKLTEDEISKILNENQPKLNLSEKQKVRWHK
                     KCLCLVEFENVEEITPLDFDHQGNMDDWLIVEKIEDVVVGTSIPYNYEKSKF"
     gene            complement(47101..47418)
                     /locus_tag="KRH23_001499"
     CDS             complement(47101..47418)
                     /locus_tag="KRH23_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HHS5224782.1"
                     /translation="MDEKMIEISFGIIGFAGDAKGLAFEAIKEAKSGNIDKARECIEK
                     SKESIHKAHKFQTELIQNEANGNKTEISVILIHAQDHLMTAMNFQQLAEEFIDVYERL
                     ESK"
     gene            complement(47431..48162)
                     /gene="chbG"
                     /locus_tag="KRH23_001500"
     CDS             complement(47431..48162)
                     /gene="chbG"
                     /locus_tag="KRH23_001500"
                     /EC_number="3.5.1.105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016811 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds, in linear amides
                     [Evidence IEA];
                     GO_process: GO:0000272 - polysaccharide catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chitin disaccharide deacetylase"
                     /protein_id="HHS5224783.1"
                     /translation="MTKIIINADDFGYCEAVNYGIISAHNNGIVRSTSMMANMPGVEH
                     GVGLLKENKTLNCGVHMTLSCGRPLLSNLKTIVDKDGFFIRRITDEIIEKMDCDEIYR
                     ELCAQIDRVKGLGIDISHLDSHHHIHTLVSLKSVIEKIVTKYNLPIRGGFEYNLEYSK
                     VVPLIDSFYKENVSEEYFIKNIDEIMKYDVVDIMSHPAFLDDYILNSTSYAIDRTKEH
                     KILTSKKVKEFLEKNGLVISSYRDI"
     gene            complement(48188..49498)
                     /locus_tag="KRH23_001501"
     CDS             complement(48188..49498)
                     /locus_tag="KRH23_001501"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008706 - 6-phospho-beta-glucosidase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HHS5224784.1"
                     /translation="MKKGLKIVTIGGGSSYTPELVEGFINRYEELPVKELWLVDIEAG
                     KEKLEIVGNLAKRMVKKAGVDMKINLTLDRREALRDADFVTTQLRVGLLDARIKDETI
                     PLSHGVMGQETNGAGGLFKALRTIPVIFDIIKDVEELCPNAWMVNFTNPTGIITEAVF
                     KYTNFRRYIGLCNVPIHLKNDVAKLFNVESDRISMDFAGLNHMVYGLNVSLDGEDVTK
                     EAIDKFVKADISMQNIKAIDFNAEFVKSLGAIPCPYHRYYYKTKEMLEDELREFKEGK
                     ARGQVVKELEEQLFELYKDEKLDVKPPQLEKRGGAYYSDAACNLISSIYNDKKDIQVV
                     NTLNKGSIRDFKDEQAVEVSSVITKNGPKPISIGYLPDSVHGLVSQIKSFEVLAAKAA
                     VYGDYESALLALCINPLIPSDDLAKTILDEMLEAHKDYLPRFNR"
     gene            complement(49595..50908)
                     /locus_tag="KRH23_001502"
     CDS             complement(49595..50908)
                     /locus_tag="KRH23_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HHS5224785.1"
                     /translation="MEKFMSFMDKYIVPVAAKIGAQRHLVAVRDAFIVMIPITMVGAL
                     GTLINNLPLEVYKNLMASIFGENWTTFGGDLWWGAIGTMAVFLVIGVAYFLAKSYESD
                     GLQSGLIALSIFFIMAPQIGKIVPEGGTTVVEGWGMIQQTYLGTAALFSSILIGLLST
                     EIFVRLSKVKKLTIKMPDGVPPAVSRSFAKLIPGMLTIMIFTVIGIFIKMLSNGSFLT
                     DILNTYLGAPLSNVADSLGSTMLIAFIIHILWTVGLHGANIALPFTETILMKLGGENA
                     ALAQAGATEGYHVLAGAFFDAFVYLGGSGMVLGLIVALLIAGRRRKEMIVLGGPPAIF
                     NIGEPLIFGLPIVLNPIFMIPFVLAPVICSAVSYLAIDFGLVAPVILPKIPWVTPPIL
                     GGAMATGDWTGGALALFNLILSILIYIPFVIASEKMEANKLKINN"
     gene            complement(50930..51241)
                     /locus_tag="KRH23_001503"
     CDS             complement(50930..51241)
                     /locus_tag="KRH23_001503"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HHS5224786.1"
                     /translation="MIKIMLACSAGMSTSLLVTKMEDAAKENGIEAKIWAISEVNLKN
                     EIENCDVLLLGPQVRYVLGKATEMAKPYNIPVEVINMMDYGRCNGKAVLDRAVELNSS
                     K"
     gene            complement(51441..52145)
                     /locus_tag="KRH23_001504"
     CDS             complement(51441..52145)
                     /locus_tag="KRH23_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HHS5224787.1"
                     /translation="MKEPIYKVIENHVRELINSDSLKEGDLIPSEKQLSEEFNVTRMT
                     VRSALNNLVKEGYITRQRGVGSIVIANNIYDNISSVSGFTKEMESKGYKVSNILVSLE
                     IVQADENLSSKLNISLEENVWEIKRVRLANDARVSYMITYMPVKLFPNLNKTHCENSL
                     YNFVEEVCGYKIAMSEREVQAVISNEECMDNLKLEEPEPLLYISQICKLQNSEIFEYS
                     HTYHYGYTLTLNAVVE"
     gene            complement(52236..53597)
                     /locus_tag="KRH23_001505"
     CDS             complement(52236..53597)
                     /locus_tag="KRH23_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HHS5224788.1"
                     /translation="MKDRLNLTEGRITEKLLKLSLPIMGTSFIQMGYNMIDMIWVGKA
                     GSKAVAAVGTAGFFPWLAMAFIMISKVGGEIKVAQSIGANNISTTKSYMKSAIEINII
                     LAIIYTISLIVLNKQLIGFFRLGDLEVITMSRQYLIIVALSMVFYFINPVFTAIFNGL
                     GNSKTPFRINTVGLITNIILDPILIFGWGFAPKLGVAGAAIATVFAQIVVTTCFIYII
                     VKSKEEYFKLRLFKEIETKYYKVLYKLGLPIAIQSGMFTVFSMLLGVIVASWGPVAVA
                     VQKVGSQIEAISWMTAEGLSVALGSFVGQNYGAKKYSRINKGCKIAITVSSVLGIITT
                     LVLVFAGESIFSIFIDESEAIEKGAIYLKILGYSQFFMCLEIITTGAFKGLGRTYIPS
                     IIITILTGARVPLAYFISRPEMLGLNGVWWSITLSSILKGILMISLFVSLLKLGKLYK
                     ISE"
     gene            54096..55250
                     /locus_tag="KRH23_001506"
     CDS             54096..55250
                     /locus_tag="KRH23_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0052621 - diguanylate cyclase activity
                     [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HHS5224789.1"
                     /translation="MKINKKFNRVDMQVSILTAIIVIISSSCVYFFNYTLTYKSMIYS
                     LSERSKHIYEYVERNIDKNTFTEINSKEDQSKKSYKSSKILLESVKNTTGVMYLYTAK
                     KTKDGSLVYVVDGLNSSRSDFRNAGDLIEKEIWGDLNKALDNHILLPKKIKSTSWGYI
                     FISYFPIHNDVGKVVGVIGIEFEAKHQYNTFKFISIVTPIIALLTCLISALIAVILFK
                     RISNPTYTDFANTDYLTGLKNRNAFEIDMNNLNNSNLKNLISIISIDLDGLKKINDKF
                     GHQTGDLYIKQASKIIQYVINKKYIVYRIGGDEYIIILKNLSHKEINNIINNINLKIV
                     EENSTNELKLSMSIGYAIFDEKVDVSLFDTYRRADSQMYDNKRKINKQYQ"
     gene            complement(55330..57048)
                     /locus_tag="KRH23_001507"
     CDS             complement(55330..57048)
                     /locus_tag="KRH23_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0033225 - ATPase-coupled
                     2-aminoethylphosphonate transporter activity [Evidence
                     IEA];
                     GO_process: GO:0033223 - 2-aminoethylphosphonate transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     permease subunit"
                     /protein_id="HHS5224790.1"
                     /translation="MNNNAISSKSISLKSKMNLDIKKCMLTVLVMSLVIFLLAPIIYL
                     FVQAFLDKDGVFVGLQNFQEYLASESLLNSLKNTVFVSVISTVISLTLALVYAYALTR
                     TKIKFKGFFKSLAMFPMFAPTMMHAIGLVYLFGNQGLVTNLLGVHVPIYGAVGIILAQ
                     IIYVFPQSFQILYISLSSTDYRLYEASNTMGISKIREFISITIPSIKYSLISSAFVSF
                     TLCFTDFGAPKVIGGEFNVLSIDVYKQIIGQQNMPMGATVSILLLIPAIISFIVTKKI
                     EKNQNSYITSKSIPYKVKTNKLRDSILGGVVGIIAFGIIAVMLTVILSSLISVWPYDL
                     RLTLEHFSMKNSIDGIKPFINSIKMSLLTAILGTSFVFLFAYLNEKTEKAPYLKSFGY
                     FLSTLPMALPGLVLGIAYVLFFNKLEFNFMDTIYIKNLFNGLYGTLLIMVICNIVHFF
                     SVAFITATTAIKKVDKELDMVAKSMGINSASILKNVTIPLCLPAVLENFMYFFLNSMV
                     TISALVFIYTASSKVAAISIVQLDDKGSTAQAAALAVLILVTNILVKVIYEFIKNRLE
                     KRTNFN"
     gene            complement(57053..58042)
                     /locus_tag="KRH23_001508"
     CDS             complement(57053..58042)
                     /locus_tag="KRH23_001508"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHS5224791.1"
                     /translation="MSYLKINNVFKSYDQKKVLNNISLDIEEGEFLCLLGPSGCGKTT
                     LLRIIAGLEDVNSGTIILQDKDITNLEPSKRGFGIVFQSYALFPNMTAYNNIAFPLKE
                     RKVSKEKIDNKVKEVLETVGLTNEAHKYPKALSGGQQQRIAIARALALEPKFLLLDEP
                     MSALDAKVRHKLRMDIKRLQKELNITTIMVTHDQEEAITMADKIAILNGGDIMQIGTP
                     EEIYQNPQNLFTAQFIGDTNCFDNGDSILTVRPEYVQIEKSTKENYQGIISNIEFRGN
                     LLRVEIKDKLNENFIISDVSIKEWVNLNLVEGDLVKISIDEKYYLKYPKVKGA"
     gene            complement(58138..59187)
                     /locus_tag="KRH23_001509"
     CDS             complement(58138..59187)
                     /locus_tag="KRH23_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009897 - external side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0030288 - outer membrane-bounded
                     periplasmic space [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0033225 - ATPase-coupled
                     2-aminoethylphosphonate transporter activity [Evidence
                     IEA];
                     GO_function: GO:0033226 - 2-aminoethylphosphonate binding
                     [Evidence IEA];
                     GO_process: GO:0033223 - 2-aminoethylphosphonate transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     substrate-binding protein"
                     /protein_id="HHS5224792.1"
                     /translation="MKEFIFTCLCIVVITFMTSCISTTPQTTQGKGNNKLTIYAALEE
                     EQIAYYMEGFREEYPNIDVEIVMDSHGVIASKLLAEKDNPQADIIWGLSAMNMIELKK
                     DGALEAYKPKNYEKVDKKFKDTEDDVSWVGMSVPETAIVVNYKELKKLGIDIPKSYED
                     LIKPEYKGLITMPNPASSGTGYLTVSGLIQMMGEKDAYNYMDKLHKNIATYTHSGSKP
                     AKLAGSGEYPIGITLGYRATQQLSSGEPIEVVFPKEGSGWDLEANALVKKDNIKKEAK
                     LFLDWAISDSAMDRYAHEVAVTSIKTDNPVPKGYSKQPFEQLIKEVDLNSAAKNRSTV
                     LKTWESKYGSKSESK"
     gene            complement(59465..60133)
                     /locus_tag="KRH23_001510"
     CDS             complement(59465..60133)
                     /locus_tag="KRH23_001510"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HHS5224793.1"
                     /translation="MARLNINPTRMEMTRLKKLLKTATRGHKLLKDKLDELMKQFLEI
                     VRENKRLREEAENALDTAYKNFIIARAVMSQEYLGSALMMPKQSVSVDVSTRNIMSVD
                     VPVFDFKTENNQSDIYPYGLAFTSGELDSAMEAFSDAMQPLLRLAESEKSAQLLAQEI
                     EKTRRRVNALENVMIPNYIETIKYIAMKLEENERASTTRLMKVKDMVLKKALEEKKKN
                     DLVV"
     gene            complement(60139..61512)
                     /locus_tag="KRH23_001511"
     CDS             complement(60139..61512)
                     /locus_tag="KRH23_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HHS5224794.1"
                     /translation="MIKEYKSIQEVAGPLMLINGVEGVKFDELGEIELSNGEIRRCKV
                     LEVNGDTALVQLFESSTGINLAESKVRFLGKSLDFGVSPDILGRVFSGMGRPIDGGPE
                     IIPDKRLDINGAPINPAARDYPAEFIQTGVSAIDGLNTLVRGQKLPIFSGSGLPHANL
                     AVQIARQAKVRGTDSKFAVVFAAVGITFEDAEFFISDFKATGAIDRSVVFVNLANDPA
                     VERVSTPRMALTAAEYLAFEQDMHVLVIITDITNYAEALREVSAAKKEVPGRRGYPGY
                     LYTDLATMYERAGKMKGHEGSITMIPILTMPEDDKTHPIPDLTGYITEGQIILSRELY
                     KKDIQPPIDVLPSLSRLKDKGIGKGKTREDHADTMNQLFAAYSRGKDAKELMAILGES
                     ALSEIDLMYAKFADEFEKEYVSQGFRTDRTIEQTLEIGWKLLSMLPKSELKRIRDEYF
                     EKYMPKE"
     gene            complement(61509..63287)
                     /locus_tag="KRH23_001512"
     CDS             complement(61509..63287)
                     /locus_tag="KRH23_001512"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HHS5224795.1"
                     /translation="MKTGTIVKVSGPLVVAEGMRDANMFDVVRVSDKHLIGEIIEMHG
                     DKASIQVYEETSGLGPGEEVVSLGMPMSVELGPGLISTIYDGIQRPLEKMYDISGTNI
                     TKGVEVSSLDRTTKWEFKPKKSVGDKVVAGDIIGGVQETAVVECKIMVPYGVKGTIKE
                     IYSGEFTVEDTVCVITDEKGNDIPVTMMQKWPVRKERPYREKKTPDSLLVTGQRVIDT
                     FFPITKGGVAAIPGPFGSGKTVTQHQLAKWADADIVVYIGCGERGNEMTDVLLEFPEL
                     KDPRTGESLMQRTVLIANTSDMPVAAREASIYTGITIAEYFRDMGYSVALMADSTSRW
                     AEALREMSGRLEEMPGEEGYPAYLGSRLAQFYERAGKVNCLGMDEREGTLTAIGAVSP
                     PGGDTSEPVSQATLRIVKVFWGLDASLAYKRHFPAINWLTSYSLYQEKVDVWADKNVN
                     DNFSAQRAQAMKLLQVESELQEIVQLVGVDSLSDGDRLILEVTRSIREDFLHQNSFHE
                     VDTYTSLHKQYRMMGLILKFYKSAQDAIKQNVTINDIIKLSVLEKIGRAKYVEEGDID
                     AAYDSIEDEIDNELADLIKKRGAEEL"
     gene            complement(63404..63721)
                     /locus_tag="KRH23_001513"
     CDS             complement(63404..63721)
                     /locus_tag="KRH23_001513"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HHS5224796.1"
                     /translation="MYKVGVVGDKDSIMGFLALGIDIFPAYDSDEIKKSIHKLVEDEY
                     AIIYITEQASLLAKESIAKYKDYQLPAIIVIPGIGGSMGLGMNEVRESSKRAIGADIL
                     FKE"
     gene            complement(63714..64691)
                     /locus_tag="KRH23_001514"
     CDS             complement(63714..64691)
                     /locus_tag="KRH23_001514"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit C"
                     /protein_id="HHS5224797.1"
                     /translation="MAEEKTYPYAVARIRVLEKQLLNRQMFIQMAEAKSPEDSLRIIA
                     EAGYADTSNNNIHNFENILTQELSKTYEILKSLAPEEKFVDVFLYKNDYHNLKVLIKE
                     EISGVDGEKYLIDGGTIPLIKLRESLANRSFSDLPKIMSSAILEAFDVYNKTQNGQMV
                     DIVLDKATFTSMKETAKESQNKFVIDYVMKVCDLTNLKSFIRVKNMKKDFDMFMNVFV
                     SGGSLDKEKFLEAFSSDTPASCFKSTSYSDVCKNGMDSGFTVFEKLCDDYLMEYVRGA
                     KFKPLTLEPLIAYLYAKESEIKTIRIILTSKLNNIDADTIKERLRDAYV"
     gene            complement(64706..65269)
                     /locus_tag="KRH23_001515"
     CDS             complement(64706..65269)
                     /locus_tag="KRH23_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit E"
                     /protein_id="HHS5224798.1"
                     /translation="MGNEQKMIDRIIADAKQEAQEILDKAKSEADLKVNSANEKAEKE
                     MASYTKLAEAEAEKAASKEISGAYMEAKKQILSKKQEILEEVILEAKNKLLNLKDNEY
                     EEIILNMIEKSNCTDDSEIVLSKKDKKTLKDVLSKKGIKVSDETRDITGGFIVKKGDI
                     EYNYSFEAIIAVEHEYIEQIAAEILFN"
     gene            complement(65321..65812)
                     /locus_tag="KRH23_001516"
     CDS             complement(65321..65812)
                     /locus_tag="KRH23_001516"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HHS5224799.1"
                     /translation="MEFLNALGNGQFLAISGAAIAALFAGMGSAKGTSIAGQAAAGVV
                     TEDPSKFGQLLVLQLLPGTQGLYGFIIAFLILSKAGIIGGDAIPTSAQGLQLLMAGLP
                     IGLVGLVSGIAQGKAAAAGVGIVAKRPEELGKAITFAAIVETYALLGLLVSFLAYNGI
                     AIG"
     gene            complement(65815..67740)
                     /locus_tag="KRH23_001517"
     CDS             complement(65815..67740)
                     /locus_tag="KRH23_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HHS5224800.1"
                     /translation="MAIVNMNKISIVGLEAQKSQILKLLMNRGFVQIDDSAFLTEEEE
                     LKNYLVKDSEESEVIMLEQKMSHVNQAINIVSSLVKQKKSLLAPKREFNKIDSEKEGQ
                     VYAEALELNNLHKEIGTIRSNINLLNNNKSMLEPWVNFDIPLENMETKYTKTILGTVP
                     ISANIDALRVKLEDEIPESVIGIVNSDKLMNYVYLITLKETFDDVLEVLKEFNFSVVS
                     LPNEEGTPLQAIKKYNEMIIRQENVSKNKTEEIKRHADSIHMLENLYDFYTIERDQKK
                     IIERLVKTKTTFCLNGWLPSKRADELIKEITEKFDCCVQTEEGSKEEGFPILLENNKL
                     VTPFESVTNMYSYPSTKDIDPNTILTFFFVIFFGMMLSDAAYGLIIAVVCGFVVYKLK
                     IQKGEGNLIKLIGICGVSTTVWGLIFGGILGDLIPIKALINPLEDVMTLMGMSLLFGI
                     IHIYVGLGIKAYTLIRSGKVIDAIFDIGFWYLCITGVCLLIIPFVAGDIGVFSEVGKY
                     LAIIGAIGLVLTQGRSFKGIPVKLFKGFSSLYGITSYFADILSYTRIMALCLTTGVIA
                     QVINLLGAIAGPILAVVIGVVGHTINLLINALGAYVHTSRLQYVEFFNKFYEGGGVPF
                     VPFKYKTKYTSINKKEM"
     gene            complement(67742..68053)
                     /locus_tag="KRH23_001518"
     CDS             complement(67742..68053)
                     /locus_tag="KRH23_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224801.1"
                     /translation="MAFEIIKSIVEAEQTADSIKVKAVTDAESIRADAVNKCESIFAD
                     VKKQAKLMEETLIEKAVTDSRAEVDKILANAKSECLKIEKTAEERKSKAIEAVIGKVV
                     R"
     gene            complement(68683..68958)
                     /locus_tag="KRH23_001519"
     CDS             complement(68683..68958)
                     /locus_tag="KRH23_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif11-like leader peptide family natural product
                     precursor"
                     /protein_id="HHS5224802.1"
                     /translation="MNEKLTKILEEAKNDDEFRKELIKTREQRDVMDSFCKVVTSRGY
                     DMTVGELFSMGEEYTSNLLKSVNGGAAYPIEDWSDWYEDFFIMLSNI"
     gene            complement(69073..70482)
                     /locus_tag="KRH23_001520"
     CDS             complement(69073..70482)
                     /locus_tag="KRH23_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase family protein"
                     /protein_id="HHS5224803.1"
                     /translation="MIDGKEVKQESGQKNLKFKIAIVVGVLFVAYIGMAIFFRNHFYF
                     GTTINGVKASGKTVEQVNDLLTSSTNSYTLNLEERNNKKEQIKAKDIDLKFTPDDKVQ
                     KIKDSQSAIGWIGGIFKSKEYNNMITLSYNKDLLEKRFNALSCFDSKNVVEPKSAYPK
                     YDSTKNAYVIVPEVLGNKVKKEDFYKLVQNSINSGNTSISLDESKVYEAPNNTKDSEK
                     LKQAIKTLDKYVGVVVTYDFSDRKETLDGSEINKWLKVDSEKNYDITFDNDAMVEYTR
                     GLSKKYSTFGDSRPFKTATGKDITISGGIYGWLIDKKKEAEALVDVVKAGKNVTREPI
                     YIQKAVSRNKDDIGNTYVEISLSGQHMWFFKNGEMLVSTDVVTGDLARGFATPSGIYP
                     LNYKARNVSLTGQGYSSPVSYWLPFNGNIGIHDATWRNSFGGGIYKSSGSHGCVNTPF
                     SKAKKIYENIEPGTPIILY"
     gene            complement(70853..71515)
                     /locus_tag="KRH23_001521"
     CDS             complement(70853..71515)
                     /locus_tag="KRH23_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="B3/B4 domain-containing protein"
                     /protein_id="HHS5224804.1"
                     /translation="MIDVSIDDKLKERWPNAKLGCIQAKVAVNKSSEKLINEINEFCD
                     TINQSLKVEDITKLDKIKDARNAYKELGKNPSRYRTSSEALVRRIIQGKGLYTINNIV
                     EINNLISIKSLYPVGTYNVSKLHSPVCFTVGDEGEQYKGIGKELINIENLPILSDSVG
                     KFGSPTSDSERAMITEDANEILICIFSFSQESDIEEYFGYAKELLKEYADGKDIETKI
                     IK"
BASE COUNT        23778 a        12446 c         8342 g        27083 t
ORIGIN      
        1 atttggatag aattattttt taaattagaa ttattttaat gaatgattca agtaataggt
       61 atgaaattga atcttttaga actgcttaca aaaaatactc aaagaaaaat agtaattttc
      121 tcagattcac aatatatttt atatgaaatg ttataaggta atctatttaa taaatttaaa
      181 tttgctatta tagatttagt tccaaagtct tactgcaaag taatatacat agttttttaa
      241 taaactaata agtgcaatta ataactactt aattgtttaa tatagtacat agataatttt
      301 aataaatcga cagttattta aaaaggtaga atcaataaaa ttatacttat aaatcttcaa
      361 tacaataatt aaaatttaat aaaaatataa ttgttgattt aactgtaatc ttatttaatt
      421 ctacctaact tattatataa aactattttt tatagattat aaaatatcta actttcatct
      481 acttcaaaga atacaatact tctccttctc ttatagtctg caatacttta atatctttta
      541 ttttcatagg gtcgattgta agtgggtttt catctaagat tatcaaatta gctaatttcc
      601 cttctttaat tgaacctttt ttatcttctt caaaatattg atatgctgca tttatagtaa
      661 caccctttaa agcatctaat gggcttatct tttcattttc tcctatttgt ataccttttt
      721 ttgtaattct attgacagca caccatactg tttccagcat attaggtgct attactggtg
      781 tatcctgatg aagagtgtaa attaatccct tttctatagt tgttttaagt gggctaatct
      841 taaacgctct atcttctcca aggtttttga tatgaatatc accccaataa tatgtgtgag
      901 ctacaaagta tgaaggtatc atatttatta ctttcatatc atcaatctgg tctgctctta
      961 ctgtttgagc atgtatcata actggtctta tatgattttc actactttgc tcttttaagt
     1021 ttaaaacttt ctcaaacgca tctatcaact ggtctgctgc tgcatctcca ttacaatgag
     1081 ttaatagttg catcttttct tttagtgaaa tatctataaa cttttctact tcttcatctt
     1141 tgtatatagg atatccacaa taaccattat ctgaattttc atatggtcta ctcaaccatg
     1201 ctgtcttacc ttgtggagaa ccatctaaga aaatcttata acctcctatt ttaaatctat
     1261 ttatatattt ttttataaac tccctattat tatctactac agacttactt tttttcaaat
     1321 ttacatatcc tacaacatcc atttttaatt tattttgatt tgccattgct tttaaaatgt
     1381 taaattgatt ttcttccatt aaaccttctt gagctgttgt aataccatag cttagatata
     1441 tgttctgtgc tttttcaatt gaattaaaaa tctcatttga tgatggttgt tttattttag
     1501 atgctacatt aaaaaatgca ttttcttcta aatatccatt tggttcttca ctgccttcta
     1561 ctctacctat atgtccacct tctgggtcac gtgtttcatt ggtaacacca agctgtttta
     1621 accccaatgt atttgcaact cccatatgac cagaagcatg tgaaattagt attggatttt
     1681 ctgaagatgc actatcgagt acactcttat ctggatgctt attttcttct aaaaaattat
     1741 tatcatatga aaatccaatt atccagtctc ctttttttat attattcgac tctttgaaat
     1801 cctgtatttt ttttactatg tctttaaaac tggttgcatc ttctaaagga actagcttta
     1861 gagtagtagc aaaagctatc aagtgactat gtgaatctat aaaagatggc atcaatgtct
     1921 taccttgtaa atctataatt tctgtatctt tatttttcaa agcaaatact tcttcttttg
     1981 ttcctatctt ttttattatt ttgtctttta taagaatagc atctccacat attgaatctt
     2041 ccattgtgat gatatttcca ttgtaataaa tttttgcttt cataaaattc tccttacgtt
     2101 gtctacttta ataaattttt ttcattattt tctgcttaat tatattatct tctttataaa
     2161 ctttttcttt agagtttaat catataaaag ttttattttt aattattgtt tgccaagaag
     2221 taaatactat tcattgtaaa taagacaaat taataggatt tatactaatt gaaaaaatat
     2281 tataagttgt taaatttaaa tatctaaact caattatatc tgtacaattg taatttttta
     2341 aatcatgatg tattatttta aatatacagt tacattatta ttcacaatat aagtatctta
     2401 gttctcaaat aacatctcat gtaatctatt caatgcaaaa aatttaaata ttttttagga
     2461 ggttttttat gagcaaggaa aataaaaatg taagaattgc tgttgtccag gcgtcaccag
     2521 tcataatgga tttagaaaaa actgttgaaa aagcattagg attaattaaa gaagctggta
     2581 gaaaaggggc aaatatcgta gttttccctg aagcattcat acctgcatat ccaagaggtc
     2641 tttcatttgg atttgttgtt ggaagtagaa caatggaagg tagagaagat tggaaaagat
     2701 actatgataa ttctgtacca gttcctagtg ctacaacaga tttattagga aaagcagcac
     2761 aagaagcagg agtatatcta tcaatgggta taacagaaag agatggtaat gatataaatt
     2821 gtacccttta ttgcacaaac ttatttttct ctccagaagg taagctaatt ggtaaacaca
     2881 gaaaacttaa acctacagga acagaaagat gtatttgggg agaaggagat ggaagtactc
     2941 ttacagtagt tgatactcca tatggaaaaa tgggttcgtt gatttgttgg gaaaattata
     3001 tgccattagc tagaacagct ctttatgcta agggtgtaaa actttacata gcccctactg
     3061 cagattcaag agaagagtgg caagcaacta tgaagcatat tgctttagaa ggaagatgtt
     3121 ttgtaattgg atgcaatcaa tatgttgaaa aaaatatgta cccaactgac cttaactact
     3181 ataaggagct agatgcagaa ccagaaatta tgtgtccagg aggaagttgt atagttgacc
     3241 cttttggaaa atatgtagca ggtcctattt tcaataaaga agaaatgcta atagctgatt
     3301 tagacctaga aaaaatagta cttagtagac tagattttga ttcagaaggt cactattcaa
     3361 gaccagatgt atttgaatta attgttcatg aataatcttt ttacacaaac atctacataa
     3421 atctttttac ataaaaaaat gagatactca taagtaaatt tcaagtatct catttttgct
     3481 taaaacctat aatcctaatt ataaatttat tcacctatat tttttctaaa tcaactactg
     3541 ttcttccaac atgttttcct gccattattg aatctatact atcatttaac tcttccaatg
     3601 atactacatt taccatatca tctaaatcat ctaatttcca ttcatttgat aataaatccc
     3661 atatttttaa tcttaagttc attgggcaat ccacagaatc tataccatat aaagtaattc
     3721 cctttaagat aaatggatat actgaacttg taaaatcaac tcctcctgca ttaccacaag
     3781 ttgttactgc tccacaataa ttagttgtct ttattgctgt tgctagagta tttcctccta
     3841 ctgtatctat tactccagcc catcttggtc taagcagagg tcttcctgag ttatcatcca
     3901 cttctgacct atgtataaca tctttaacac ctaagtttag taatacttct ttttgttctt
     3961 ctaattttcc tgttgaaact acaactgaat aacctaattt aatcaatatt ttagttgcaa
     4021 ttacagcaac tcctccagta ccaccagtga ctaatacatc tcccatattc ttgtctacag
     4081 aatctataaa cttatacaca gataaagctg ctgtaaaccc tgctgtacca taatccattg
     4141 cttcttttag tgaaagattt ttaggaagtt taactaccca actagaagga actcttatgt
     4201 attctgaaaa accaccagaa gtattcattc ccaagtcata acctgttact aaaacttctt
     4261 ctccaatttt aaaatcatca caactactag attctactat accagatgca tcaattcctg
     4321 gtgtatgagg atactttctc gtaacaccct tattaccatt tgcagaaagt gcatccttgt
     4381 aatttaaaga agaatatttt acttttatta gaacttcgcc ttctggcaat gtatctactt
     4441 ctctttcaac tatatttctt ctaaaatttc cttcttcttc tgtaatatat agtgatttaa
     4501 attttttatt cataaatttc ctcccaatac atttagtttt atgttaaact aattatagtt
     4561 tataaatagt tttatgtcaa actaatttaa atagattaaa gattggagaa taatttatgg
     4621 aagataaata tattgtacat ttcataagta aaacaaaggc tagtatgatt aaattcattg
     4681 aaaataaact cagtaaaaat ggtttaggtg agttaatacc tactcatgga aatattttaa
     4741 ctgcacttta tgaaaataat ggaatactta caatgaaaga aattgcagct aaaataggaa
     4801 aagataaatc cactgttaca gtgttggtta ataaacttat aaacctagga tatttagaaa
     4861 gacaaaaatg tacaaatgac aaacgtatca cgtatataaa gcttacaaaa aaggcactgc
     4921 ttatagaaga tacttttaat agcatctcaa cacaagttaa agagacagca taccataata
     4981 ttacagaaaa tgaaaaacaa gaatttctta gaattttaaa aaaaattaat gataatttta
     5041 aaaatgctga ctaaattgag cataattata tctcctattg gaataataaa taaaaagaat
     5101 caaatattgt aaaaatttat tatgatagag aggtagaata tgaatttaaa agatagtaaa
     5161 actaaagaaa atttattaag agcttttgca ggtgagagtc aagctagaaa tagatacaat
     5221 atttctgcat ctgtagcaaa aaaagaagga ttatatataa tagagtcttt atttaattac
     5281 actgctgacc aagaaaaatc acatgcaaaa caattctttt ctaaattaaa agaatttgct
     5341 ggtgaaaata taagtatatc aggagcatac cctgtagatt tatatgacaa gacagcacaa
     5401 caccttaaag ctgcacaaca taatgagctt caagagtggg atgatgtata taaaaacttt
     5461 ggaaaaacag cacgtgaaga aggatttgaa tctatagcta agttatttga aaatatagct
     5521 gaaatagaaa aagttcatgg tgatagattt ggtagatatg ctactgattt agaagaaggt
     5581 actttattca gaagaaatga agatatacaa tggatatgta cacattgtgg ccatatacat
     5641 ataggtaaag aggctccaaa agcttgtcct gtatgtcttc atccacaagg atatttctta
     5701 gattttaaaa actcattatt tgaataaact aaggtaatca ttgtatttaa acaatttact
     5761 atatttatat caagtatttt tataaatact gtattatctt aataacaata aaatgaacca
     5821 ttgatattac tataagtaga aaatgtagtt taaatacaat ttatagtagt tcatcatggt
     5881 tcattttatt gtttactaat ccctataacc tacttaaatc tatctttaac ttttacacac
     5941 tcacataaaa tctcatcttt aaactaaata tttaaataaa gtgtatttta agtatattat
     6001 tataatacat tatataagat aatacactat gataacttta tacttatatc atttatttct
     6061 tttgtcaagt caacctcaat aatcttaact acatcttttt caaactttac ttttttataa
     6121 tccaaacatc ctactacgaa tggaactcca aactttctaa acaaataaat ctttccactt
     6181 tcattgtata ttgatgtaaa attttcttct attatattca ctatcaattt taactcttca
     6241 aaagttatta tagatttaac taaaaacttc tctattatgc tcaatataag cagttctttt
     6301 ttacctatgc tttgctcttt tttatataaa ttttgaaata tttctttggt ataattacat
     6361 ataacttctt tactgagaat aaaatcaatg tcaaattctt tattaatatc ctttttcata
     6421 aacatatttg caatatcatc aagagaagtc tcttctttca tagacaatat taactctatt
     6481 ctttctagta ttttatctct tggaaagaaa gtctcttgac ctgtaaaagc tgattttttt
     6541 ataaaccatt cctctggtat tatgtttttt cttttccatc tatataattg accataagat
     6601 atattagttt tgctcaataa atctttctta gatattaatt cttccataac ttttctagcc
     6661 cacctttata ctgtttttta cagtagaatt atctgaaact gataaattat cactgtattc
     6721 aatatttcca acgtcacaat tatctactag agatatgctt ttacctcgta tatcttttat
     6781 tgatgcatct tctaattcaa tagtatctcc ctctatcaaa ttacatttaa actttcctga
     6841 aaaaatatta atgattttaa ttaatgaaaa agcatctttg cttcttccta tttttatatt
     6901 agttgcccct atctctttac aataagaacc tcctcctgaa taaacatata tattttctcc
     6961 atttaaaaga ccatcacatt ttattactcc atataccttt atatcttcac attctatatt
     7021 tgatttattt ctcatttcgc catagatttt tatatcttgt gcatacatat tttcatttac
     7081 acttaattgt cctcttattg taacattatt acatttaagt ttgccatcca ctttctgttg
     7141 agcagttata actaagtcat ctatttctgc atctccctct atattaagtt gaccattcac
     7201 tcttacacgc tctgctttaa gattgcctct tataatagtt tttccattaa caacaaaatt
     7261 ttttatattg atgtcacctt caaattttgc atctccaagg acttttactt cgttactttt
     7321 aacatttcct tttgatttag aacttcccac gatttttata ttttcatact caccactact
     7381 tataaagcct tctccaagta tttttataga ccctttttcc atattattac ctcattttaa
     7441 attttatttt taaacctatt tattacttat ccttctttaa ttttattttt tcacttatat
     7501 tctttatttc accaactatt gaatcttcat caatctctat actttcactg tactccaaac
     7561 tttctacata acatcccttg cctattttaa tattttttcc tcttacaact ttgacttcac
     7621 tattttctaa gcttatttca tctgcttcta taatatttgc aaacaattta ctttctgtat
     7681 actttctaat tgataataga cctaaactta ttaaatttga agacactttt tcaaagttga
     7741 tatgcttttt ttctagcata cgaaattttt tgcaataatc tccatgcccc ttttttatat
     7801 ttatactact tgctccaact tcattaaaat tagaagttcc atttaaacta atattaactt
     7861 cttcacaatt caaaaatcca ttacactcca agattccact taaattgata ttttcacaat
     7921 ctatattctc atttgctttt aaatatcctt ctccatgaat aatatccgat tttatacttc
     7981 cttctacatt aataattcca ctagtatcaa tttcaacaga attaatattt cctgtacatc
     8041 taagaagtcc cgatatctca acttttgatg ccagtatgtt tccttctact ttacttaaac
     8101 cagatgtaaa aaattcatta cattctgttg tcccaaaaac ttttgctgaa ccagaagaat
     8161 caaatttact acattttaca cttccttcta ttttgcctgt tcctgatata ttaacattat
     8221 caaaaattcc acctttacat tttccaacac catcaaatct tagtgaactt aattcttcat
     8281 tcataatgat atcctttctt taccgtattt tatctttaaa cctaatataa caaaacattg
     8341 ttacgttgtc aagtgtgata ataatactta ataaggcaac tatcatttat tttctataaa
     8401 tgggcataaa aataataggg aaatgcttta tttaaactat aaatctaatt tcttagattg
     8461 tggtttaaat aaaatatatc cctattactc aatgtttata tattcattgt ataaacttct
     8521 aaaatataag tctttaaatt ctactgtcaa tactttttat acactgtttg tgctatcatc
     8581 tcacacacct aaaggagtag gctttgcgca ctattctgta acctacaaga cactatcttc
     8641 ttctatctat tgataaattt ttctattaca tcagctagtc tctccatatc agttggataa
     8701 acttcaccta tgctacctat tctaaatgta tctatatcag tcaatttacc tggatagata
     8761 acaaatccat tatcttttaa ataagtataa aattccataa attcaaactt tgcattttta
     8821 ggatataaga aagttgttat tacaggtgat tgagcattat cattcaccaa agtatcaaat
     8881 cctaaagatt ttaatcttga agctattgta aactgatttt ctttatatct agcatatctt
     8941 ttttcaacag aaccttcttc ttccaattct aataaagctt gataaaaagc tcttacaaca
     9001 tgtgtaggtg aagtaaatct ccatttacca ttatttttct ccatagtctc ccattgcgca
     9061 tacacatcaa gagataatga tttagctata cctttacatt tagataattc ctctttatta
     9121 gctattataa aaccaaatcc aggtactcct tgtatacatt tgttagaact actaactaaa
     9181 aaatctatat taaaatcttc aacatcaatc tcaattcccc caaaactact catagcatca
     9241 actatataaa ttttgttata ttcttttgca agtttcccta cctcttgtat aggatttaat
     9301 ctacctgtag tggtttcaca gtgaaccatt gatatatgtg ttatatcctt gttttctttt
     9361 aataaatttt ctactacatt taaatccact gcttctatat ctttaaaagt gcagtcaaca
     9421 aattgtatgt taagataatt acatatatct ttcattctct ttccgtatgc tccatttgca
     9481 attacaagaa gtttaccatc ttttgaaata gtacttccta ttatagcttc tactgaaaaa
     9541 gtcccacttc cttgcattaa tacacttgtg tatttatctg tattttgggt tgctagagat
     9601 actaatcttc ttctaacatc ttgtactagg ttattatatt caacatccca agtacaccaa
     9661 tcttttaaca tagatgctct tactgattta gtagtagata gtggtcctgg tgtaagtaat
     9721 atgtaatcat tttctggtac aaaatctgat ttaatagttt cattctctat ttttattagt
     9781 atatcttcta actcagccat agtttctatt acaaaatgtg ctcctgcctc tttaaatttc
     9841 tttgaaacta tactcatctt agattttaat tcttccttat ccatgttctc tacttcttct
     9901 tgtgtaagcc ctaactcact tgaacctttt attacagcaa cactccacat tcctgcattt
     9961 acgccttctt ttacatcact tattgtatct cctactttta ccatagaact cataggagac
    10021 acccctaaag cttcagcatt tttatagcac atccaaggat atggtcttcc ttgagatact
    10081 tctgatggtg ttacaagaaa atcgggtgag tatcctttct ttgctgcatt tggttcaact
    10141 atgttcatca tctctcttgt ataacccgtt gtagaaccta tttttaatcc attttctctc
    10201 aacttttcaa tagtttcaac aacatgagga attggagtcg tatactcttc taatgtctca
    10261 aataacattg gttcaaattc agcataaagt tcatttacat catcttcagt tggcacttta
    10321 ccaaacttat ctgaccaaag attttttatt ctatccattt cacacatttc tcttatatgg
    10381 tctattttta attttcccat aggttttctt gcttcttcca ttgttacatc tatacctctt
    10441 cttttaaata tctctataaa tacattaaga ggtgcaaaac atccataatc tactgttgtt
    10501 ccagcccaat cgaatactac tgcttttatt ttttctccat atatcttttt catatttata
    10561 gcctccatag attcttttag aatttttgtg tttttaattg tttttacttt taaagtataa
    10621 ctttcatatg ttaattatac atcatattta ggttaaatat atattaaatc tctgttttta
    10681 gttgtattta gttgttttta ttttgtataa tatttccata aaatcctaag ttacaatcta
    10741 aaatttactt tctaatctta atctatgaac tgactatatt ttatgaattt agttgtatta
    10801 agcatagttg tattatataa aactaaaggt ttattttgct tctatccatg ttatatttat
    10861 ctcatttaac ttatccttcc attcattcgg aggttctaca tcacaaataa caaaatctaa
    10921 ttcctctaaa tctgctatct tatacatact agcaattcct attttagaac tatcacataa
    10981 tacaaaactt tcctttgaat tttttatata ttcttttgac aacaatgcct tattttggtc
    11041 tatactacta attccaaaac tatcaagtat accttcacta gatataaaag ctttatctac
    11101 gtataagttt ttcatagtat ctattgacat tggacatgct gtcctttggt gttttaaatt
    11161 tacttttcca ccaataaata taacttctcc atcaaacaaa ccttgattct cgtaagaaat
    11221 caattttgat agaactggat aagagtttgt aataattttt aaattgttta cagatattat
    11281 ataatctaca atctgcaaat tggtagtacc ttcatctatg ataattgact cattgtcatt
    11341 tacaaactta gctgcatatt tagcaatact ttgcttttta tctaggttag tattgtttct
    11401 ctttatatgt tctggttcaa tcactccata atttattttt atagcaccac catatacctt
    11461 ttttaattta ttttcatttt ctaattcttc caaatatctt cttattgttt ctgatgatac
    11521 ttctaatctt tttactaatt ctttagtgtt taccttccct tttgaatcta ataatttaag
    11581 tatttctttt tttctatcta tcgaatttaa agacattcat tttcctccta aatataatat
    11641 atttttctcc tataatatta caatgatacc taagatttat gaaatcatat ttatatatta
    11701 aattttttac ttaattaaag ttattttcaa aagactttgt attatcatta aaaaagtcca
    11761 tcaaatatta gtatcagatg gactttgtaa aattttattt tataaattaa tatttaaagt
    11821 ctaagtacta atttattttc ttgtctccaa gaattttact aaattattta cagtagacat
    11881 atcttttctc tctaaatcag ttggttgaag ctctatccct aatctatttt caatttcaag
    11941 taaaacttca attatagcta atgagtctaa aagttccgtc tcaaataaat taaggtctaa
    12001 atcttctctt atctcatcag tccctaatac atcttcaaat atttctataa ctgtttcttg
    12061 cataaatttt cctccttaaa attaagctaa ataacctgag aatatcagca atccaaaaca
    12121 cacaatatgg aatgtaatga aaatctgcac tctctcgaac catttatctt ttttatgttt
    12181 tttataaaat ttagattttc gctgatatat atcagttaac acaagtgcca atccttggta
    12241 tacaccataa gcaacataat accaagttag accatgccaa aatcccattg ttatcatggt
    12301 tatcatctga gccacatgag cagcagtagt ccttttctta aatcttttct ttctcattga
    12361 tgacataaca aatctagaaa aaatataatc tccaaaccat cttgaaagac ttatatgcca
    12421 tcttgtccag aactctttca tatctttact gataaatggc ttgtcaaagt ttataggtac
    12481 ttgtattcca aatatgtatc ctgtacctat agcaaataaa ctatatcctg caaaatcaaa
    12541 gaacaggtat aaactatatg cgtacatata acttaaaata tttataaaac tcatatcttt
    12601 aggtattctt gatacccaat atgtatttat caaaaatgct ataacaaact tataacctac
    12661 tcccatgaca atatttttta ttcctggcag taagtattct tctatatact cttttctaga
    12721 gatttgtttt tccaagtcct gttcaaatct tcttgaccta tcaataggtc cagaacttaa
    12781 agttggaaaa aataacataa aataaagcat ctttgaaatt ttaacttctt ttatagctcc
    12841 atcataaatt tcaataacca tttgtatagt tctgaaattt aagtatgata ttccaataaa
    12901 tccaattatt ccaaaagaag taactggaga tattttattt attattattg ggagcattga
    12961 tgcaaacaag aatccccaat atatgtattt atttttagtt tttcttctta catattcgta
    13021 tcctttaact attattactt caagaataat aaatattacc aagtacttta gttggacatc
    13081 aattcctact attaagaata tcataaacaa acttgccaac ataccataat actttatatt
    13141 cttgcccatt agacctaaaa ttactgctgg tattgatgtt aataataata tataaagata
    13201 aaaataatct ccatattgtg aaaaaatcat taaatttcct ccataagttt ctttctgtct
    13261 attttaccat tgatatttgt tggaaactca gagattattg aaatatttct tggaatcata
    13321 tatgaaggta tatactttcc aagttccttt tttattatca tcccattttt aatattactt
    13381 aaatcattct tttcatttaa ctcaacaata ccttttaagt aagcaatttt ttcgtcctta
    13441 tatactggta aaactactgc attttttaca ttatgtactt ttctcaaatt attttctata
    13501 tcttctattt caattctaaa tccatttaat ttaatctgaa aatcttttct tccacaataa
    13561 tatatatttc catctaaaag atatcccata tctccagttt tataagctct ccactttaca
    13621 ccatctattt catcatagaa aaatacttca tcagtctttt ctttattatt gaagtaacct
    13681 ttagaaactg atggtccaat tattataatt tcaccctttt cattttcttt aagctcattt
    13741 ccatcttcat caagtatttt tattttacaa tttgacatag ggtatccaac tggaagactt
    13801 ttttcatcat ctatagcctt ttgagtcata tcatttacac ttacaccaac agtagcctcg
    13861 gttggtccat atccattgat aattcttgtg tttggaaatc tactcataag ttctttagta
    13921 agattttttg aaagtgcttc tcctatgaat atcattgact caaggttagg aagcatttta
    13981 ctattaaact ctttttcagt tatacatact cctgcaaaag aaggagttga cacccataca
    14041 gctatatctg agatactaaa ttgtctaaat agttctttat agtctgctaa tacatctttt
    14101 gatattgaaa ataatgtagc tccatggata agaccagggt atattgttgt aactgaaagg
    14161 tcaaaagaat atgctggttg gttcattatt actttttcac ttccatctat gtttagatat
    14221 gggcttatcc aatctgaaaa gctatctaaa ttgtttgaac ttatttgaac cccttttggc
    14281 tttcctgtac ttcctgaagt aaatagtata tatgcatttt catcatcttt tacccagttt
    14341 tctttatcta atgattttcc ctgatactca tttattatgt catttaattt atccatatca
    14401 attacattga tatctccaaa atttctttca tcactaaagt taaataatac ctttggtttt
    14461 atctctttag tgacttcaaa aactctatca attggaaaac taatatcaag aggcacatac
    14521 gctctacctg attttaaagc tcctatcata catgccatta tcatgttttc tttatttcca
    14581 taaattacta taggagtatc ttcttctttg tatacatcct ttagaaatac tgatatagca
    14641 tctgaatatt catttaaatc tttataagaa agtttatctc cattacacat tagtgctgtt
    14701 ctatctgtat ttgaatattt ttttattcct tcaataattt tcatataaga atgctccttt
    14761 aaaatccgtt ataaataaat ggcaattctt taaatggagt aaatgttaga actcctatcg
    14821 ccaatattat aaccatagtt aaacaaatac tagttaacaa atctttattg ttctttaaat
    14881 attttaaata atctctcaca gacatctacc catcctttcg taccaagatg cattacatcc
    14941 cttaaataat acttatctga ccctttatct ttaaggttta gaacttcaaa gcctttgctt
    15001 tctgctattt tttgtgcttt atcgtagtac tgatttcttt ctttttcaga aataccagtc
    15061 aaattataga atttatccat acttgggatt aatacaacaa ctggcttaat acctaagtca
    15121 gtacatacat ttagcataag tttataattt tcaaactcct tagatgttaa taaatttaca
    15181 tctttgtctc ttcctttgta ttgctctata ccatctttaa aatgctcttt ataatagtac
    15241 ttatcaatat ttagtggatt tttaccaact ctttttttag catcttcaat ggctttcttt
    15301 ctctcatatg accaatttat tggtcttttt ctttttgttg ctctcttttt atctagctta
    15361 attaatcgtt tataaagaat acccttttct ttaagagcta tacagtactt tcttccttga
    15421 aaataaggct ctaaaagcac cttttcagct ttttcaggaa atgtcttagg ctcatatagc
    15481 ttagcatata atgcttctgc tttatactcg tcacttcccc ataataactt acttgatttt
    15541 tttgcatatt caatcttatt ttgtttagat atttttggat tatctaaaaa tcgataaaat
    15601 tgtattggtg aaaatctaga ctgataatgg tgacttgtga ctccatcttt ttccataaac
    15661 cattgcatag aaattaacaa gacaactttc ttattatcaa tattaggatt catacttcct
    15721 aatattgcag catcttgtaa tgtctgagta taggctctcc caattgcaaa caccttattt
    15781 ttactcctat ttgtattaaa atagtacttt ggatgttgtt ttgttgaatt actaagttct
    15841 gatgacccca aaatcataat atccttttct cttaaaaaat gattatttgc tgtaacccct
    15901 ttatctttta tatcacttaa agtatcatcc ataattggaa gtagattttt ctccctcaaa
    15961 agttcatcag ttttagaatc aagaaatttg tctaacccaa ataaaaatac tacgcctatt
    16021 ataaaaggtg taataaagta tatcaatttt ctcatatttt ctctcctcta aaaatattca
    16081 aatttatgtt attattaatc atattagttt tgatatgtat attcaactac aaaattgtaa
    16141 taaaatcgtc aaaacttttt ttgatactgt tacaaaattg taaaaaaaaa gaaaaaaacg
    16201 ccaaaaataa atttcttttt agcacttttt catacttata atttgacatt ttaacacttg
    16261 gctaagtata caccttacct taacttaaaa ttaaatttat ttaagaatat atattataaa
    16321 ttcttatatt ttctaatata aactatatac tatcagctgg ataaacaata ctactttgtc
    16381 ttcttatctc atccataatt tccattacta ttattgaatt ttcatgagaa tttatatttg
    16441 attctatttt attgttattt ataagactta taaactctac aagttcataa tacattcctt
    16501 ctatttctct aggcttttcc tctgcttttt cttttggaat agatatatct tcttctcttc
    16561 catctctgta tttaataata gctttttcaa atagattaag cttttcaatt attatacttc
    16621 cctcttctcc ttgtatttca gatggtatat aagaatcagc tactttagaa tactgaatta
    16681 tcgcatccat atcatcatat tgaaatacag ctgaaccttc tccatccact ccagtttgaa
    16741 gtatatgaga aactgccttt acagtttttg gagcaccaaa taaattcacc ataggatgta
    16801 tacaatacac tcctatatcc attaaagctc catttgacaa ctctttttta aaggcatttt
    16861 ctataattcc atttttatat ttatcatatc ttgaagaata ctgacaatag cttccaaaaa
    16921 atcttcttat tttccctatt ttatataagt tttctttaac tgctttaaag tttggaacac
    16981 atgtaattct catagcttcc ataagcaata cattattatc tttggctgtt tttatcattg
    17041 atttgacttc ttttaaatta gatgctaacg acttttcaca aagcacatgt tttttgtgtt
    17101 ttaaacaagt aatggtttgc tttgaatgta atgcatttgg agaagctatg tatacagcat
    17161 ctatatcctt cgatttagcc atttgttcta aatcatcaaa aaaaatactt gctccatata
    17221 gagttccaaa ttctctagct ttttctaaat ttctagaata tacagcaacc aattcaaagt
    17281 ctttaaccct agatgcagct cttagaaata tatttgctat attgcttgtc ccaacaatac
    17341 caaatcttat tttacccatc ataaatcact ccccattttc tacactttat tttaatttta
    17401 ataaaaaact ttacaactta tagatatatt ataaaataat tttatcaaat aaaaaagaaa
    17461 gctaatttta aatgatttca ccattttaac atagctttct tttaactaca atctaaattc
    17521 aacttatatt tttaaagtta tctttctact atatctttat ttcccctcaa aaattttata
    17581 gtaagaattt catccacaaa caatgttact aaaagtatag ttacaacaat tggccaataa
    17641 ggtattataa gactatataa gctatcaact atatacactt gaaaatatct aactccaata
    17701 aatgtcaata tagtccaata tacagaaaac tttagacata ctattcctct actattgtac
    17761 ttataatctg aataatccca atagacctta ttaaaatata ctttcataag tattcctgta
    17821 atatattcta ctactgtcgg cactactaga cataataaaa gcaatgcaaa tatattattg
    17881 gggtcaataa atcttgagac ctctattata atcgacattg caattgcata cattggttta
    17941 aatggaccat ttaaaaatcc atcttcttga aaatgccctt gtttataata actatataag
    18001 ttttcaatta tccaacctat aaaaccatac aagaaaaaat taaataaaaa atataataga
    18061 gaacctacat tatccatgaa tattcctcct agctgtttat acttattttt tctcatattc
    18121 atggatttat tctaaatcaa agaaattata tttaatttat ttaattaata ctttatatta
    18181 tagattgtga cattctttag agtttaaact ttttaggtat tctctaactt ccagtaaatt
    18241 ttcaagtatc ttatgtgatt gtgatttaat ttgctcatct ggctctttta aatctggtac
    18301 atttatacat cttataccac cattgtatgc agcttcaact cccataggcg aatcctctat
    18361 gacaatacaa ttttggggat taacatttat ctttttagct gcttttaaga atatctcagg
    18421 gtttggttta gagtttacaa catcatctcc acaaactata gcatcaaagt aatcttttaa
    18481 atttgcctta gctaatctct ttactgctct ttctctcttt gttgatgttg caacagccat
    18541 tttgtatcca ttttccttta aaaaagagat tagttcattg actcctaatt tgataggagc
    18601 tcccttcctc tccataaatt caatcatatt tttagttttt tcgtcatata aatctattat
    18661 tggtacagaa ctatcgtata tatctgtaag accttctatt attcctttac gatttcttcc
    18721 cataactgat gtataaattt ccttagtcat agtatatcca tacttttcaa acgtctccat
    18781 ccaaaattca agagaaattc tctctgagtc aaacaaaact ccatccatgt caaaaataat
    18841 tccttctact ttttgcatac aattcctcca atattttttg atataattat attacacttt
    18901 ttatgattaa ttttacaacc ctcaatttat ccaattctaa tattgtaaaa ttgtaatttt
    18961 caaaagttac actttggttt actttaatat ttgaaccaag catataggat atccatccac
    19021 ctatactgtc aaatccatca tgctctatat caagtccaaa atacttatta atatagttga
    19081 tagattcagt tccatcaact aagtaagaac ctgctcctat tttcttaata tgagtctctt
    19141 ctttatcaaa ttcatcttga atttctccaa ctatctcttc tagtatatct tctattgtta
    19201 ccacaccaga tgtaccacca tattcatcca caactatagc aagttgaagt ttttcctttc
    19261 ttattctctc aagagcttta tctatagtta aattttcaga tatatatata atatctctca
    19321 atatttcttc tagttcaatt ttattttcat ttatcttttg attgtataaa tctcttatat
    19381 gtacaaaacc taatatatca tctttatttt ttctgcatac tggatatctt gtaacacctt
    19441 cctcttttaa aatagctaat atcttttctt cagaatcact ttcatatata cataccatat
    19501 cagttctagg aaccattatc tctctaattt tcttttcttc aaattcaaaa atattatcaa
    19561 ctaatctttg ctctgattca tctataagtc cacttttata actttcttct actaatagtc
    19621 ttatttcgtc acctgtatgg ggttcatcaa cctcatcagc ttgtgaatat ccaaatggtt
    19681 taagaaataa atcagtactt aagttgaaaa aatatattat tggatatgtt aacttataaa
    19741 atcctactaa taaaaaagat gtactcaaca ttattttttc tgtattataa agtgctaaag
    19801 ctttaggaac caactctcct attacaacct ccatcattgt tataattaaa aaagaaatgg
    19861 aaattgatat agtatatata atactttcac taagattaaa tacacttact attggtaaaa
    19921 ttaactcttt aactgtagat tctcccatcc aacctaatgc aagtgaacaa agtgttatac
    19981 caagttgaca tgcagaaaga taggaattta agttgtcttt tattatttta catctttttg
    20041 cattattatt accttcagtt atcatggtat caatcctaga actacgaagt tttaccatag
    20101 caaattcaca agctacaaaa aaagcattta tcaaaacaag cattactata agtgttactt
    20161 ttaataactc ccgcataaag tattggttct tataatgtaa gaaatctata agaactcaaa
    20221 gttcccccct tatatttata aatttaattt ataatatata ttctatcata tttattaata
    20281 tatcctactt tattacaaat aatttttata aactaaataa ccccttttaa tatttatgac
    20341 tggctatttg ataaatatta aaggggttat ttagttatca ttttttattt ctaaaaatct
    20401 tttctcaaat gatttagtta tctatttatc caatttttta cataatttaa tgattaaaaa
    20461 tattaatttt ttcactataa agtataaata ttttttgtat aaatattatc tgattattaa
    20521 aagaaatatt aatactataa ataaaaacga agcatgattt ttatttaaat aaatctcaaa
    20581 cttcgtcttt acttacttag atatttattt actttctaaa tcctattatt tttaaaacct
    20641 tatcttttta atacttcacc acatttattc tcagtaatct ctccattttc caacgcaatt
    20701 tttccattta caattacata ttcaacacca ttggctagta attgtggctt tgaaaaatca
    20761 atatcttctg acctaggata actatagtta tccatgtcaa taactgctat atcagctatc
    20821 aacccttctt taagaatacc tctatttttt attttaaatt gcctagctgg taatgaagta
    20881 actcttctta caatctcttc caatctaaca ccagactttc tgtacatatt gaagaaaatt
    20941 ggaaaagctc ctcttctttg tagttcaaac catgacatat ccccacccac actaaacaaa
    21001 caatctgaac caaccataac aaatggatta tcaattattt tatcatcatg tagtttatct
    21061 gggaaatcag ctctatacat tcctcctaaa caaaagataa gttcttcgtc tccatctaaa
    21121 agtaaatcga gtaataactt gtcctcatct attccttttt gtgtagctat ttcacgtatt
    21181 gatttctttt ccatattaat atctttagtg tttagaagta ttatactccc cctatctcca
    21241 agtataaatg cttcttttaa tataagtgtt cttccctctt catttctaag agcatccatt
    21301 accccattta tacctaattc aaatagacta gatgatattg ccataataaa ttgaattact
    21361 ctttttttct tcatacaatg cccagaactt cttggtactg tgtcaaccat tatttcaaca
    21421 ccattatacc tagcctttaa tatctcatca aatgcttcta tttcaactgg acttaagtga
    21481 gatacttgaa ccctagcgcc acttttttgc ccaacctcta tggcttcttt tactgcatta
    21541 tatcttccta tgtaatctct aatatgagat gtatatatac catcatactc tttaatctgc
    21601 cttgcaatat caacaagttc atcaatatca gcatacttac ttggtatata tgccaatcca
    21661 gtagatattc caaaagcacc acttttcatt ccatcattta ttatatctgt aatttcattt
    21721 ttttcctttt ctgtaggagg tctatcctta gaacctccca taacactcca tcttatagtc
    21781 ccatgcccca acaagaatcc catattgaca gaaataccac ttttagatat aaggtcacaa
    21841 tattctgtaa aattattcca acatttattt ttatctataa gatacttttt ttcttcttca
    21901 agtaatagac catttttata catatattca tatacatttt cagaagaata tggtgttata
    21961 gaatgtccac aattaccatt tatagttgtt gtaactcctt gttttagaaa cttttcaaat
    22021 ttaccatcta gtattgctac tatttcttca tgaacatgag ggtcaataaa tccaggtgtt
    22081 ataacttttc cacaacaatc aatctcttta tttgtattgc tatttatctt agaatctatt
    22141 tttgctatta agttgtcttt aattgctata tctccataaa aaccaggatt acctgtacca
    22201 tctattataa atccattttt taagattaaa tcatatatca aaatattccc tccttaaaaa
    22261 ccaattttta aataatctta atgtaatttt tatatttgaa aatcaaatta ttaaatttca
    22321 tatttgaaaa ttcactatta tttcattgta attagtcact aagcttatct ttatacatag
    22381 ctcttgcaat taatatagta ccaaatacac atataagaac tactagagac tgtggtatta
    22441 taccttgctt tgataatata atagtcaata cagatattac aattgctact agacctaatt
    22501 ttttatcttg taaaaatact tgtccaaaaa ctgacccaaa tagagctggt aaaattaagt
    22561 ttaatttttc tactacttca gctggaattt tagatagtac gcttcctcct aaaattaccc
    22621 ctatagttag tatacttata ttcactaaaa tagatacagc tattcctatt gtagatatta
    22681 tcgagccttc ttctgtacct gattcaactt ctgctgcctt ttgagctgct attgaacatg
    22741 gtagcctcat attagatata ttaccagaaa gaaaactcat ataagttcct gggataccta
    22801 agattggtga ataagaaact ggttctatta tgtaatttgg agcactcata ctgacaattg
    22861 ccattgtact tgctaataat gctgatattg gaggcataat accaaatcca aagctcaaaa
    22921 ttattccagg aactaatgct gctataatac ccaaagatag tgttagtctt ccatacctta
    22981 tcataaaagg taaatactct tcattgtata tagattttac tttactcata aaactccctc
    23041 cttatattac tgaagctatt atcattccgc taaacattga tattgtaagc ccccactctc
    23101 ttaaccattt tatatttttc ttcttttcaa gcatacacaa tattaccatt atagccattc
    23161 cacttataca tgcaattgtt ccattatcaa aacgcaacac cctatcagca tttagatatg
    23221 caaatgaacc caacattgct cctagagata ttattggtat aaatgatttc ttgccactag
    23281 atataacatt ggttatctta tctagtttat gtccaaatag taatgtgaat attatccatc
    23341 ctaaagaacc taatatcata gtccaaactg catttgtaaa tgcaagtttt gtcatttcag
    23401 gagaacctaa agttatacct aatgcatctg ttccaaatcc ggctgacatt gattcaaaaa
    23461 ttacagaacc tataaatgat aatctcatcc atgctatagg cccacccata gttactataa
    23521 gcgataccat tccagcaaat atagtcattg aaggcccaat agctgaaata gcactactct
    23581 taacagctga ctttatttgt ttatctgtta ttcccattgt tttaccaact ttgcaagatt
    23641 ttatagcaaa tataagagat tgtaccacta ctattgatac tgctactgta ctcgctatcc
    23701 acaaaagtgg atgattagct aattttaaat aatccattta taaaacctcc ctataaatcc
    23761 tcaaatttta ttaatatttc taatatatct atttccaaac ctgttttagt actctaagta
    23821 tatttccacc tagtaccttc tctatttcct catcactata tccatgcttt actaaatatc
    23881 taacaatgtt ttttgaagtt tctgttgggt tctcaagacc ttttacatat tctactttgg
    23941 gatgttcttt tgttcctgtt atttttttta tatcaaattt agcagctagt actgagtgta
    24001 attttacatg gtcgccatat actgtatctg gtccaaaagc tacatggtct attcctacta
    24061 aatttttaat atactcaaaa tgttccataa atgactctat tgaatgttct ttattcttct
    24121 ctgttattgt agtatgaggt gctgcttcta cacctataac ccctcctttt ttagcacatg
    24181 ctattaatac ttcatctgga gttagtctct ttgtgttcca taaacttctt gccccaacat
    24241 ggcttaatat tattgggtcc ttgctatatt ctattacatc aagtgtagtt tgaactccaa
    24301 cgtgagagca atctattgcc attccaattt tattcattct ttcaacagct tttttcccaa
    24361 aatttgtaag acctccatct ttctcttctt ttagtcctga acctaatgca ttggattcgc
    24421 tgtatgttat acccattaac cttataccaa atccatacag tatatctatt ctgtcaagtt
    24481 cattttctat tggtgctgca ccttctaatg ttggtatcaa tgctacttta ccttcacttt
    24541 tagctctgta tatatcttct actttttcac actttatgac aaaatcttga tgagctaaat
    24601 cacatagtct catgcctaaa tctattaata tatcatccca tttccaccct gaatttgatg
    24661 ttatcgtaca tacaccatcc attaaattat caaatatagc atcataatat cctcttgata
    24721 atgcttcata agcgcatctt tgtttacctt ccctattata ttcaaatata tctctttcta
    24781 ggtgttctgg aaataatact ggatgttcat gtaatgatat aaatattttt tcatccacta
    24841 tacttttaac cttcgcttct tgaatatcat ctaattcaat aaggtactct ttaactcttt
    24901 tatctccttt acacatctca atagatgaaa tatcttttcc tttttctaaa taactatagg
    24961 cttcatatcc tttgtaagct gacttcataa caacatcctc caagttctac aattttttat
    25021 atttttccta tgtagcaatt gatgtgccaa aatataaatt ttaattgtat aataaatctt
    25081 gcaaaaaata aaaacagtag taaggttgat atttactact gttttattaa aaataatctt
    25141 cttagattat ttattcaata tttttgaatt atcttaatct taaagataat tttatttatt
    25201 tctatccatt atagggattt ttttagggtg ttttgccttt ttagtcccct atatcactcc
    25261 cttaattttt acatatgata taaagttctt tccttcatca gttataaaac taccttgttt
    25321 ttttactcca gataaaagta aaccatggct ctttaactta tctattcttt ttctaatttg
    25381 gtctacactt aaaactatat ctttttcttt taaaatctct tgcagtttat ttcttcctaa
    25441 taatatattt ttattattcc aagtttctat actggtcaat atacatatac tttcctcaaa
    25501 gaaattagat tgtttgaaat ctaagataat tgaatcgaaa ttttcattaa ctaaagtatt
    25561 gtttttttca aatctaaatt gttctggcaa atgctcgtaa tctactctat cttcctcaac
    25621 tatagtatca atataataaa ttaaattttt aagctctctt acatttcctg gccattcata
    25681 caatgttaaa gcttgcattg attcctctgt aaaacatttg ttgctattta tttcatctaa
    25741 aaaatactta cttataagag gtatatcttc cttacgttct ctaagtctag gtatctctat
    25801 atgtaataca ttaatcctat aatacaaatc ttctctaaaa gaaccttctt taattttttt
    25861 ctttaaatct ttatttgttg cagctataat tctaacatct attggtataa ctttacttcc
    25921 gcccattctc ataacttctt tttcctgtaa tactcttagc aatctctgct gtacatctaa
    25981 agatatatca cctatctcat ctaaaaaaat tgttcctgta tgtgctcttt caaatatacc
    26041 catttttcca ccttttattg ctcctgtaaa acttccttca tcatagccaa aaagttcact
    26101 ttcaataagt gtatctgaca aagaagatag attaactgca acaaatggct tgttttttct
    26161 tagagattca ttatgtattg cctgggcaaa tatttctttt cctgttccat tttctccaag
    26221 tatcaacaca gaaaagtctg tagttgctat ttttcttgca atattaattt tttcttttat
    26281 tattttactc tcacctacaa cactctcaaa tgtatacttt gatacaaaac cttttgactg
    26341 aagtttattt tgaatcttgt cctcaagcac ttgaattgca cttatatttt taatgcttat
    26401 aatactcttt attcgttcat tattttcata aacatttact ttattaatta tcagtttttt
    26461 gttatttaaa tttactactt catcattaac ttcatcttct tgaaaaaata tttttttgac
    26521 aaccttatca ctaaataagt ccataaagtt attagatata atttcatttt ggtctattcc
    26581 aactagatta gaaaatactt tgttgcaata tataaatttt cctaatttat caacagaagc
    26641 aataccttca tctataatct ccaaaaaact cttcatggtt ttattcatag ttgtataata
    26701 cctatatcca cttactgtat cttcattgta tttttcctta ataatatgta gtttatctat
    26761 agatatattt agttttgtaa agatttctat aactgtattt atatcaatta ccttatcacc
    26821 tatgtcaatt atttgcttta tgttttgtgg tatgctgttt ctgcttcccg taataattcc
    26881 aatctcacat ttagacttat cacaacctgg ataatatggt attagattaa tatgaattaa
    26941 tcctagtttt ctaattatct tggcagtttc atctgctgac tctttataag catctataac
    27001 cataacatca gaatcatttt ctatacttat tatctgattt atattttcaa tatttatagt
    27061 acgatgtact attacaatag gtatattttt atcaatatta ttatgtatat attcctttat
    27121 atcattgtct gaacatacca caagctcata gcttgacagt tcaatattta tcctatttac
    27181 atataccaag ttatctatat tacaaaattc tccaaatata ttttccaatt gttttgatat
    27241 atctatattt attttgtcat cagttgatac aaataaaata ttatgttttt tcatagtccc
    27301 acctcctgtt taacgagtat agaaagtaat aatttggtct attgtagcac tttttaaaaa
    27361 agttttaaat cttaaaaatc aaattttgta ccatttacta ttattttcca taataaaata
    27421 atgtaagcta tcttttttca catataattt aatttctaaa acggttagtt tgacattatt
    27481 ggaatataaa caaaaattta atataaattc gttaatatat taatacattt ttaagaatga
    27541 taaggaataa attataacaa attttaggaa tatataataa tagggtctca gaacttagtt
    27601 acaagttcta aaaccctatt tgtttagtgt aaaaaacatc ataaaattta gcttaaatct
    27661 tttcacataa tattactctt tttctaagtg ataataaaat atatctattc ctctaaaaac
    27721 tgtaaaaatt cctgattaaa tagtttaagc tcatcataga atatagcatg accactatac
    27781 tcaaaagtat ataaaattga atcttctatt ttttcattca taaaaactgc aaattcatac
    27841 ggacatattt catctaattt cccatgaaat ataccagtag gcactcttac acattttaaa
    27901 tcattaaata attcttcatc tcttaaagat acagcagttc caatagtgcc aatacctgat
    27961 gcactaaaac caatatcatt aaaccatctt ctaaagcttt ctggtggatt tgatgcaaat
    28021 actttttcgc caaaatcggt taccatttct ggtctatcag tacatgcttg tgctatcaat
    28081 ttatttacat cttcacgtgt cataccatat ggaaattctg gaggtctttg tacaaatgat
    28141 ggtgcagcag ctgcagctaa taccaatttt gacactccat atccattaaa taaactcata
    28201 tacctaagta cgattgctcc tcccattgaa aaaccaacaa gggtaaagtc ttttaatcca
    28261 atagcatgta ccaccttata aatatcgtct gctaattggc tataagtata tcctcctgat
    28321 gttgcatcag atttaccaaa acctcttaaa tcaattgaaa ctgttctata tccgagtttt
    28381 ggcaatatat ttgtttgata ttcaaatatc ttatgtccta agggccaacc atgtataaaa
    28441 agtacagttt ttttagcact cggattcaaa tcatatactg ctatatttat atcattcaca
    28501 tatacataat acatatcaac agcaactccc ttcaagaaaa tgtatgatgg ttattttata
    28561 tatatgaata aaatgatgaa taattaaatt ttcaaattta tttacaatac ttctctattg
    28621 ccttttcaaa taaacttaca tgaagttttt catctaggat tattctattt aatatagctt
    28681 ttatataagg gtcttcaata agacttatat ctttataata attattaata gccacatgct
    28741 ccaaatgcaa atctagtttt agtctgttac aaatagaatt tccataacat acaaaaccac
    28801 cattccaata tgcaccacaa gaacttgtag aacctctata tacaggattt ccacccaata
    28861 atcttatagt ctttgctaat atctccatat gtaacatttc tgttatagat atatttatcc
    28921 acatttcact taactctcta tgcgtttcat ctaaatcaaa attatggtat agatattgat
    28981 ttacactcgt aaattcactt gatactccag catagtcatc catcaataat tctgcatagt
    29041 actatttgga cctaaaactt ttatctctgg atatggctca tcacttgaat atccatttcg
    29101 cttgtgcatg tcataatgtg catcactcat aatatctcct cctttaaatt taatgtatga
    29161 tattaattgt atgcatcaca actttttcat ataacttaga taataaaatc tacttaaata
    29221 ataaaaagcc atattaatta aaattaacat gaccttttat ccacaaaatt actttttaat
    29281 tattcatctt ttccagctac tgatagctct ttaataacaa ctgaaggtga acctatacta
    29341 ctcattggaa attctaaatc ttctcctata gcttcaatat ctttcaacag gtcaaaatag
    29401 tttcctgcta ctgtaatttg ctccactgga aatacttttt ttccttcttt gatataaaag
    29461 cctttggcag ctaaagaaaa gtctcctgtt actgaatttg cacctgaatg aagtcctgca
    29521 aagctagtaa ccatcaatcc ttcatctata tcctttataa tttcatctaa agatttatct
    29581 cctttctcta tataaaaatt agttggatat atgcttatag gtgatgaata tgaagatttt
    29641 attccatttc ctgtagtctt tacacctgcc ttattagccg tttttaagtt atgaagtaaa
    29701 gttataagct ttccatttaa aacaacttct tttttaaatg tagctactcc ttcatcatca
    29761 aaaggagtag atgccatacc attttctaaa agtgggtcat caactattgt aactatagga
    29821 gatgctatca tgtctccttc tctatttttc aataaagata atcctttttg agctgaatct
    29881 gcattaaata tcccagaaaa tgtgctaagc aaagatacca tagcttcatt aagcaatata
    29941 gttttatatt tacctgatgg aatactctta ccacctactt tagataaagc attatcaaca
    30001 ccaagttttg ctatctcaca aggttttatt tcttcaatag aatttgctat attatatcct
    30061 attccatcat atttttgtcc attgtcttct atgataggaa ctacaaaccc tataagcata
    30121 ttagttttat tgcttaaatt aagaccttta gtattagata taccattact tgatacagaa
    30181 taagatatag tacatttaga taaatttacc accttatctg aataagcttt agtctctctt
    30241 tccatttcta aagctaaatc aatcaactta tctgcctcta aattttctag ctctttagaa
    30301 taagtcttta catcattata gtgcttatct ccttcatata taaattgtac atcttcattt
    30361 tcaatagtgt ttactccatc ttttacattt tttatcaaca tatcaacagc tttatcatct
    30421 aaaatttctg tataagaata acctatcttt ccatttacct tacctctaaa agataaacca
    30481 aaagatttat caagattgta tttctcaact tctccttcat atatatttat acttaaattt
    30541 tctcctgtat aataatatat ttcacactct tcaaaacctt cacttagagc ctttttaaat
    30601 aatatatctt taaaattttt aagttccaca attatccctc ctatcttcca cctacagtaa
    30661 tttcttttac ccttatcata ggttggccta cattagttgg tatacttcct gatgatgagc
    30721 cacacatccc ctgagcttgt tttacgttat tcccaaccat atctatattc ataagtatat
    30781 cgctaccttt tccaattaaa ctagcacctc taactggctc ttgtatttct ccatttttta
    30841 ttaagtaacc ttctgaaact gcaaaattaa actctcctgt tacaggattt acagaaccac
    30901 cacccatttt tttagcataa agtccatctg gtattgactt tataatatct tctggtttat
    30961 cctctccagc agcaatataa gtgttagtca tccttgaagt tggtgcaaat ttgtagttct
    31021 gtctacgaga acttcctgta ggattcattc ccattcgtct accattaagt ttatctatca
    31081 tataagactt caaaattcca ttttcaatca gtatattctt ttgagttgga tttccttcat
    31141 catctatatt catagaaccc cagtagtttg gtattgtacc atcatctata gctgtaatct
    31201 ttgtggaagc aatctgttga cctaatttat ctgcaaatac agagttcccc tttgcaactg
    31261 atgtagcttc caaagaatgt ccacaagctt catgaaatat tactccacca aatccattat
    31321 ctattgctac catcatatta cctgcaggac aatttttagc atgcaacata gtatgcgcta
    31381 ctctagctga ttcttttgca taatattctg ggtctatttc ttcaaatatt tcaaaccctt
    31441 tacaacctcc agggccttca aatccagttt gattttcatt gcccttagat gcaattgaac
    31501 ttatccccag tctggttctt attcttctat cctcaacata tataccttca gtgtttgcaa
    31561 ttaatatttt ttggtcttta tccaaatagc taacacttac ttgagatata tcattactaa
    31621 attcttttgc actcttatat gtaaccttca taacacttac tttatctcta tttcctattg
    31681 aatttggata aatttttata ttatgtatgt tatttatttt aatactgtca tttaatatta
    31741 cactttttcc atcttccaat tttcctaaag caacagcagc tttgtatgct acatccaaca
    31801 gactatttaa tgaattgtca cttgtataag catatatact tttcaatcct ttaaatattc
    31861 ttattcctat gccataattt cttccaccta ttgcattttc tactttatta tctattaaac
    31921 taatagaatt atttatagtg tcttcttcaa aaatctcagc aaaatctcct ccagtaatta
    31981 gacacttttc taatacctta gaagctatat tttttgaaag cataaattta cctcctactt
    32041 taaattttta attaactttt attcaatctt tttacttgtt aacaaacatt atatactata
    32101 ttacttaaaa taaggtaatt atgaatatat tatacatatg ttttatacta aaatgttatc
    32161 acattttatc tgtacatacc catataacta gataattaaa atgtataata ttatttgcta
    32221 tagaaaataa tacactcata cataataaat tttaggagtg aagtatatga atcaagaata
    32281 tgtaaaagga aatcctattt ttactaatat taataaagtt ccaagacaat ttccatacct
    32341 tactgatgat attgatactg atgttataat tgttggtggt ggcgtaactg gatgtatttg
    32401 tgcttactat ctagctaaaa acaatataaa gtctgtcatt cttgaaaaag gaaggattgc
    32461 acatggaagc actagcgtga caacttctct attacagtat gaattagatg acaatttgat
    32521 agatttaaca gaggttatga ctctaaaaga tgctctaaaa gcatataacc tttgtacttc
    32581 agcacttgaa gaattagata catttataga gctatatgga aataagtgtg attatgccaa
    32641 aagagatact ctactttata ctgccaacaa acttgaagtt aaggctatca aagaagaata
    32701 taacttaaga aaagaaaatg gatttgatgt tgaatatatt gatgaatcca caaacccttt
    32761 tagctttgat ttaaaatcag gattgatagc aaagaatgga ggacgagaat tagacccata
    32821 taaatatagt caccatttga ttgatgtaag tttaaaaaat ggtcttcaag tatatgaaaa
    32881 tacagaagta aaaaaagtag atttatcaaa tgataaggtt actgctgaag tatcgtatgg
    32941 atacaaagtt catggtaaaa aattaattgt agctacaggg tataatacaa gtttatttac
    33001 aaaaagaaat tttgcaacta agtcaaatac ttttaatata gcaacgaaac cacttaaaaa
    33061 catagcttct tggaaaaaca acattttaat tagagataac tgtgacccat ataattatct
    33121 aagaactact aaagacaatc gattaattat aggtggtgaa gatgtaaatt ttgatgatat
    33181 agaaaatgaa actttagcca atgaaaagta cgatatttta gaacaaagat tgaaaagtat
    33241 gtttaaggat ataaaagaca ttgaagttga atataaatat tgtggttgtt ttgcttcaac
    33301 tttagataat ttaggtttta ttggtccaga taataaaaat aacaatctat ggtattgctt
    33361 aggttatgga gcaaatggta tactctttgc aatattagga ggtataatgt taagtgaatt
    33421 atatcttggc aaacaaaata aaaatatgaa attatttaaa gtagatagat ttgataaata
    33481 gatattatat attaaaagac tgtaaaaaga tgaaacttta taattctaaa agttaacttt
    33541 gatacagtct tttataatgt tccttttaaa aatactttat ttataattaa atataaagta
    33601 aaatgttaaa atataactga taaaatttag tcataagata atatttaagt ttatttgatg
    33661 aaatatggag gaattattat gaaggaaata ctcgttattg ctcccactaa aggaacctat
    33721 gaaaaatcaa ttcacatagt taaaaaaaac aaatataaaa atattgatgt tgtatttggc
    33781 aatctaaaag aaggtatacc tcttgctgaa aaaagtatta atcatggtac tagaattatc
    33841 ataagccgag gtggaactta caatatgtta aaagctactt acaatatacc tatagttgaa
    33901 attaaggtag atgcttatga tattataaaa agctacaagg aggtaaaaaa ttccaacgaa
    33961 ccatttggaa taattggatt taataatgtc atctacggtt tcgatattat agaagaaata
    34021 ttgaataaga aaataactat gattgaaatt gaaaaagaag aagaaattta tgatgctata
    34081 gaaaagtaca gaaagaaagg tataaacaca tatataggag ataccactgt tgcacatatt
    34141 gttaagagac ttaattgtaa gggaatatta atcgaatcta gagaagaaaa catacttaga
    34201 gccattcaac aagcagaaca aatactcgaa gcaaccaagg atgaacaaaa aagaagatta
    34261 cagatagaag ctatgacaga ttttgtacat gatggaataa taacagttga taaaaatttt
    34321 aaaataacat tatttaataa gagtgctgaa aaaatatttg gtataaaaaa agaaaatgca
    34381 ctttatcata atgttgtaga tgttatccca aacacagttc ttccacaagt agttgagact
    34441 atggaacctc aaattggtga aatacaaaat atagggagta caaaaattat tacaaataga
    34501 gttccaataa ttgttgatgg tcagattcaa ggggctgttt caacatttca agatagcaag
    34561 gagataagtt cttttgaaca tacaataaga aggagcttat taagcaaagg tctatctgct
    34621 aaatacactt ttgatgatat aattcatgct agcgaaaaga caaaagattg tatagaactt
    34681 gcaaaaaaat atgcttgtta tgatactcct atgattatta ctggagaatc tggagttggt
    34741 aaagaactat tttgtcaaag tatacataac tatggtaagc gtaaaaatgc accttttgtt
    34801 gctgtaaatt gtgctgccat acctccatct ctaatagaga gtgagttttt tggttatgag
    34861 gaaggttcat ttacaggtgc tagaaaaaaa ggtaaagcag gtgtattcga actagcacat
    34921 gaaggcacaa tcttcctaga cgaaataagt gaaatccctc ttgaacttca aggtcgatta
    34981 ttgagggtat tgcaggaaaa acaagttatg agaattggtg gtgataaagt tattcctata
    35041 gatgtaaaaa ttatctgtgc ttcaaataaa gacttaaaaa atatgatgcg caatggttta
    35101 tttagacaag acctttattt tagaataaat atactaacat tatatcttcc ttcattaaaa
    35161 gaaagaaaag aagatattat aaaattatca gaatttttta tacataaata ttcaagcaaa
    35221 tacaataaaa cgcctttaat tatcactcca aatattaaaa aggcacttct tgaacgagaa
    35281 tatgaaggta atataaggga attggaaggt atgatggaaa gggctgttat tgtggaatca
    35341 tttgactcga ttttattaga aaaggttagc aatgaatata caaataatat agttgataaa
    35401 gataatagtg attttgaatg cagtaattta gatttaaaaa ctttagaaaa aaaatatatc
    35461 tataaaattt ataacgaaaa taatagaaat actacaaaaa cctgtgaaat tctaaagata
    35521 actcgctcca ctctatggcg taagttaaaa gaaatagaag atgatgttta aaaataatac
    35581 atatctatat atatcaaaac gttttatgtt taattttaat acataagacg tttatttgtt
    35641 ttcaataaaa aatacaatca tatgataaaa agaatctttg taagtgaaat tctcgtcaat
    35701 cgtactttta attataagta atctacagca tttcaatcga ttattaaaaa taatcatgat
    35761 aactaaagat acaaactcta tatattggca tagtaattgc ttttataata cctatataaa
    35821 aatgaaaggg agtgatacta gatgcacatc ttaaaatcag tgaaaaagat accaggagga
    35881 cttatggtct gtcccttgtt attgggagca ctatttaata cagtatgtcc acaagctctt
    35941 gaaattggag gattcacaac atccttattt aaaactggtg caatgagtat acttgctcta
    36001 ttttgtctat gcaatggagc tcaaatcaat atcagacaag ctggtaaacc attgactaaa
    36061 ggtatagtac ttacagcaac aaaatttata attggtgcag tattaggtat tattgttagt
    36121 aaatttattg gacctaaagg tataattggt attacacctc ttgccatagt tgctaccatg
    36181 actaattcaa atggaggtct atttgctgct cttgcaggtg aatatggaga ctccacagat
    36241 gttggagcaa tatctatctt atctctaaat gatggtcctt tttttacaat gcttgctttt
    36301 ggagtaactg gacttgcaaa tgtacctata atagcactat ttgcagcact tataccaata
    36361 ctacttggat ttatacttgg taaccttgat gaagatatac gagaatttct tgcacctggt
    36421 acaacattat taattccttt ctttgctttt cctttaggag cagcattaaa ctttaatcaa
    36481 attataactg ctggactacc tggagttgta cttggtttag gagttactat aataacaggt
    36541 atgggtggat actttgtaat gaaacttata cgtgcagaac atccagcagt aggtgcagct
    36601 acaggtacaa cagccggaaa tgcagctggt actcctgaag ctttagcagc tatagaccct
    36661 actctagcta caatagcagc tgtttcaaca gtacaggttg ctgctgctat tattgttaca
    36721 gcaatatgtt gtccaatgtt agtttcctat ctagataaaa gagaaaaaaa gaaaaaatct
    36781 atttttaaaa caaataaaaa tattgaagta aattaatact taaggaggta aaattaatga
    36841 atgcaattat tcatgcaaat gaaaaagata atctagttac atgtgtcaga cctttagtta
    36901 aaggtgaaaa agtttcaatt gatggaaagt cttacatagt aaatgataat atacctgtct
    36961 ttcataagat ggctacagaa gatgtaaaaa aaggtgatgt tgtatacaaa tacggtgaaa
    37021 ttataggaat tgcaacagtt gacataaaaa ctggtgacta tgttcatgta cataacattg
    37081 aaagtacacg tggtcgtgga gataaaaaat aggaggaagt taaaatgaaa ttaatgggtt
    37141 atttaagaga aaatggtcag tttggtattc gtaatcatgt tttaattatt ccaacatctg
    37201 tatgttcaag tgagacagct acaagaatag catcacttgt gcctggagca atagcaatcc
    37261 ctcatcaaca tggatgttgt caaattggtt ctgatataga gcttacagca aagacattaa
    37321 taggatttgg aaaaaatcct aatgttgccg cggttttagt agttggtctt ggatgtgatg
    37381 gtattcaagc aaaagaatta gcatctgaaa tagctacaac aggaaaaaag gtagattacg
    37441 ttgttataca agaatgtggt ggaacattaa aaacagtttc taagggagct gaaatagtaa
    37501 gtaaaatggc tcgcgaagta tcaaaagaag taagagttga atttggtatg agtgaaatta
    37561 cattagcact tgaatgtggt ggttctgacc caacaagtgg aatagcttca aacccttcaa
    37621 taggcgttgc atcaaacctt cttgtagatg aaggtggaag tagcatacta agtgaaacta
    37681 cagaagtaat tggtgcagaa catttgttgg ctacccgttt tgaagatgaa gaaatgaaag
    37741 ataagtttct taaatttgta agtgatgtag aaaaaagagc aattgctatg ggagaagatt
    37801 tacgtagtgg tcaacctact ccaggcaata aaactggtgg actttcaaca attgaagaaa
    37861 agtcacttgg gtgtatgtat aaggcaggca ataagccatt caaaggtgct cttgaatatg
    37921 ctgatattgt acctcctgat aaaaaaggat tatattttat ggatactcca ggtcaagata
    37981 tagattctat cactggtatg gtagcaggtg gtgcacaaat tgtaatcttt tcaactggta
    38041 gaggtactcc aacaggaagc cctatttcac cagttattaa aatcactggg aatagtgata
    38101 catacaacaa aatgccagac aatatcgata taaatgcagg tagaattata acagatggtg
    38161 ctaaaatagc agatataggt caagaaatat ttaatgaaat aatagaagtc tgtaatggta
    38221 aacataccaa agctgaaagt cttggtcata gagaatttgg catttacaga atttcatcta
    38281 cattttagat tgtaacaaaa tatcttttat aaatataata cttatgtaga tacataagct
    38341 aaaagttctt tctaatacta taaaaatttt ctatactgaa aaggaactgt atcaaaatta
    38401 ttttgaaaac agttcctttt ttcacctctt ttactcaaaa tattataaaa taagatttaa
    38461 acaataaacg tatcttgatt aatatctaag aagacataaa taaatctaaa tgtaaagtga
    38521 gataaataaa atttaatatc tttgtatgaa aagatatttg gtataatatg tctgagagaa
    38581 ttcttatttg taaacaaata aaggatggag gatgaaacaa aagaatgaac tttgaaaaca
    38641 caaaaaataa aaaaataata gctactttac tattgacact ccttttaatc gtgtcattaa
    38701 catgtgtcac ttttattatg aatctaaata aagtaacaca taatgaaaca gaacgatatc
    38761 ttgtagaagt ttcacaaagt atttccacta caattaatgt gaaatgtaaa agtatattta
    38821 ggacactata ttctatggga gatacttatt ttgagattaa tgatagtgaa aaagaagtca
    38881 atagatactt atcaaaaaaa ttaaaattat ttgaatttga ttggttaggt attatagatt
    38941 ctaatggaaa ttttgtaagt gcccttaaag atacaggtaa tgttaaagga caagactttt
    39001 atagaaaagc ccttcaaggc aaagaaacaa ttactcctgt taaatcacaa tctggtacat
    39061 atggaatttt atattctgta ccactataca atggcgataa aattgttgga gctgttgctg
    39121 cttggaatac tattgatact atgagaaatt tattaagtgt agaaagcttt catggtgaag
    39181 gattttccca aattatcgac caagatggaa attttattgt aagttcagca aacaaaaatg
    39241 ctccaaaaaa tgtggtaaat ttttttgaca tgattaaaca ccaaggaaaa caggttgata
    39301 aaaataaact tgaagaaatg aaaataaact taaaaaagaa caaaactggt tctatgtatt
    39361 atacattaaa tgatggtatt tctaaggcaa tgcattatct tccattacaa gaagaaaact
    39421 tatacctcct ttcagttgtt ccaacaaaaa cagcaagtgc acagtttgat ttacttctaa
    39481 aaaaagcaat cttcatcaat attttaattg ttatactatt tttattgctt attatattga
    39541 ttatgtttat aaatcaaaag aacagggcac aacttataaa aatcgcctat gtagactctg
    39601 taactaaagg ttacagtaaa gcacgttttg atattgaagc taaaaaaatt atacagtcat
    39661 cttcatcaga aagctattca ttggtatcta taaatattca gaaattcaaa cttattaatg
    39721 attcttttgg tagtgaagca ggagataaaa cattaaagta catacatgat gtcattagta
    39781 attatctaga accaggagaa ttgctttgtc gagtttctaa tgaccagttt aatgtactta
    39841 ttaaaactat tcctcaaaaa gaaattctta agtacataga aaatatcacc aatgatatta
    39901 atagcttcaa taaaaatgaa gaatgtaaat attttatagc tctatctata ggtgtatata
    39961 aaattgatga cccaaatcta cctttagttt caattcaaga ccgtgcaaat gttgcacgaa
    40021 aaaataataa aggaaacatt ggaaatcatc cactttatac atgtgttttt tatagtgatt
    40081 tagagcgttt aaaaatgatt aaagaaaaag aaatggaaaa tagaatggag gaagcattaa
    40141 ataataacga atttatagta tatcttcagc ctaaaataag cctcaaagat aatactattg
    40201 taggtgcaga agcattagta agatggcaag acccaaataa aggtcttata ccaccagacg
    40261 agtttattcc tttctttgaa aaaaatggct ttattacaaa actcgaccac tatgtttttg
    40321 aaaaagtgtg tagtatgata agaaaatgga tagataatgg agaaactcca atacctgttt
    40381 cagttaattt ttcacgtgct aatttaaata atatagattt tttagaaaaa tacagaatgc
    40441 ttcgtaataa atacaacatt cctgctaagc tcttagaaat tgaattaact gaaacacttg
    40501 tatttgaaaa tctccaaaaa ttaattaata taatagacca aatccatgaa gaaggttttc
    40561 aatgttcact agatgacttt ggaagtggat actcttcact caatatgtta aaagaaataa
    40621 aagttgacac attaaaactt gaccgtgctt tttttagctc acctaatgca gataatattg
    40681 ctgaaaatca tgtaatagaa tctatagtta atttggcaaa aaaattaaat atgaatagta
    40741 tatcagaagg tgttgaaaca atcttgcaaa tggattatct taaaaaaatt aattgtgata
    40801 tgatacaagg atatgttttt tcaaaacctc tgcctcaaga aatatttgag aaaatgactt
    40861 ttggaaaaaa actagaagaa accagtatgg atagttccgt ttaaataaaa taaaaaactt
    40921 gtctctataa aataatttta atcattttat aaagacaagt ttttttattt tccaatttaa
    40981 ttttattttc taaatttctt atactcggct tgttttaaat tcccttttta agaataataa
    41041 tacgattatc atagcaataa aatctgcaac tggctgtgcc aaccaaacac catctaaatt
    41101 aaattgaatt ggaagcacaa tgattaatgg tataaataaa ataaattgtc ttaaaagagt
    41161 taaaaacatt gaatgtttaa ctttacttat acactgaaaa tacacaggtc ctacaataga
    41221 aatccccatt ataggcaatg taattagatt tatgcttata cctcttactg ctatatccat
    41281 caaatctgaa tccttattaa atatacctac aaatacttct gggaaaactt gtactactaa
    41341 aaatccaaat gacaatatga caactgacac tatgatagat aatattaaag ttttctttgc
    41401 acgctcatat tgttttgcac cataattgta tgatattata gtttgcatac cttgattcaa
    41461 tccaaacaca ggcatcataa acatcaataa aatagatgta agtgctgtca tagctccaat
    41521 agctaaatct ccaccataaa cctttagaga attatttgta aacatgtgag ttatacttat
    41581 agctacttcc atagcaaaag gtgtcattcc tattgtaaat accttcttta ctatatcttt
    41641 attcaatttt aagttacatt tttttagttt taaattggac ttccctctta taaaataatg
    41701 tattacccaa aagaatacta ctatttgaca gagtactgtt gctatagctg ctccttttat
    41761 acctaaatta aatacaaata taaatatagg gtccaatatc aggtttaata cacatcctac
    41821 aatcattgtc cttgctgcta attttggatt accttctgcc ctaattgcat tattaagaga
    41881 aaatgcaact aaattaaata tacttccaac caatatgaca ctcatatagt cttttgcata
    41941 aaatattgaa tctttacttg cacccaaaat aaaaagtata tcttctaaga aaactaatcc
    42001 taatatagtt ataattaaag agataattat agataatgtt aaagcattac ctaatatctt
    42061 ctctgcttct tctctatttc tttcacctaa ctttatagac aatcttgtgc tagcacctac
    42121 tgataccaac attccaaaag ctattattag agtaaatact ggcatagtta caccaagacc
    42181 tgcaatagct atagagccaa taccttccat agaaccaata aaagctctat ctactacatt
    42241 ataaagtgaa gttaccatca ttgctattat tgcaggtatc gaatacctaa ataataaaat
    42301 ccatattttt tcatgtctta atgcttcttg attctccatg ttgtcaccat ttataccatg
    42361 tcataagtta tacaaattgg tttatttgtt cttgggtctg ttgctatttc tgcatcaata
    42421 ttaaataatt cctttagatt atctttcgtc ataacatcat atgcatcacc ttcacaaact
    42481 attttacctt tcttaatacc tatcatgtgg tcagcaaatc ttgctgcatt attaagttca
    42541 tgtattacca tgacaatagt tcttccttgt tttttattta gttcatctaa taattttagt
    42601 atctccaatt gatgtgccaa atctaaatac gttgtaggct catccagtaa taatatatca
    42661 gtttcttgtg ccaaagccat agctatccat gccctttgtc tttgtcctcc tgataaatct
    42721 tccatatttc tatccttaaa ttctgcaatt ccagtaactt ctaaactcca atttacaatc
    42781 tctctgtctt ctttactaga attaccaaat ccacttttat gaggaaatct tccataagaa
    42841 attaattctg aaacggtaag accactagga gcttgagggc tttgtggaag tacagccata
    42901 tcttttgcta tttctttaga cttctttttg tagatgtcct ctccatttat atatattttt
    42961 ccactattag ggctaataat tctacctata gttttaagta ttgtcgattt tccacaacca
    43021 ttagccccta tgatggtagt tatttttcct tttggtatat ttaaatttaa attttttata
    43081 atatctgtgt ttccatatga tacatttaga ttcttagtat ttatacagtt cataacaaca
    43141 ccctttccta atcatttacc aacattaaat aaataaagta cggcactcct attatagaaa
    43201 ctactatacc tactggtatt tctataggtg ctagaagatt tcttgatata gtatctgcta
    43261 ttaaaagtaa taatgttcct atcaatgctg atactggtat taatctttta tgctttggtc
    43321 ctattatttt tctacctata tgtggagcta ttaaacctaa aaatgaaata ctacctgcta
    43381 ctgctgtcga tacaccagat aaaattactg catatattat aagtcttctt ctttgttttt
    43441 ctaaatctac accaagactt atagatactt catcacccaa atttaaaaca tctatatatt
    43501 tagatttata aatagttata cccataaaaa tcactataaa tggaagcaca gctattacat
    43561 atttccaact ggttccccaa atgcttcctg atgtccatgc cataacccta ttaaattctt
    43621 gtgttgtaaa tttcaattgg aatatcgtca aaattgaagt aaaagctatg tttacaccta
    43681 taccaataag tagtaatctt gacgaattta taccaccttt ccatgcaaga gaatatataa
    43741 gaaatgctcc aaataaagct cctataagtg caacaatagg cattgtaaat acagtcaagt
    43801 tactcatacc ttcatataca ttaccattca taaggtatat ataaactact acaaacaatg
    43861 cagcacctga atttattccc aaaattccag aatcagctaa atcatttttt gtaactcctt
    43921 gaagtattac acctgctgtt gataatgcag aaccaaccaa aagtgctatt actattcttg
    43981 gtaatcttaa tttaaatatt gcaatttcat gattacgctg accctgccct aaaaaagtct
    44041 ttataacatc cattggttct atagaaaatg agcccatatt taaactcaat aaaaaagtga
    44101 taaaaataag caccattaaa attgatataa caagtaatgt tttagaattt atttttataa
    44161 tatttttcat agtacctatt tctccccctt tctaacaagg tatataaata ttggcactcc
    44221 tataagtgct gttatagaac ctactggtgt ctcatatgga ggatttatca tcctacttaa
    44281 tatatctgta tatacaagca atacagctcc taatactaaa gagctcggta ttatatactt
    44341 ataatctgaa cctactattc ctttagctat ttgaggaact ataagaccta taaaaataat
    44401 attaccagac actgacacag atgctccagt cattaatatt acaagtacta tacatataaa
    44461 tctaacaaag ttagtttttt gtcctaatcc tattgccact tcttctccaa gacttaatat
    44521 agttattctt ggagccataa taatagctaa aataaatcca ataccaccag ctacaaatag
    44581 caattttata ccttcccact tcactcctac aagccctcct gatatccaga aacttaattg
    44641 ttgagatagg ttaaaataca tagatattgc tgatgccaaa gaaattagca atgtaccaag
    44701 agcgactcct gcaagagcta attttacatt attaactctt cctcttgatt tagaacttat
    44761 aaaatatata aataatccac ttatacttgc tccaataaat gcaaacatca ttacactaaa
    44821 acttccatgt ataagttgag gaagtttttt ttgaagtacc agtgatatcg aaattgcgaa
    44881 tgtagctcct tgtgtaattc ctataacaga tggttcagct ataggatttc tcgttattcc
    44941 ttgcattatt gccccagaaa ctgctaaaaa ccctccaaca agtgcagctg ctattgccct
    45001 tggaagtcta acatccttta ctattctcat atttattcca tcttccattt ttatcaaact
    45061 atctataaca gttgatagat tcatatcttt tgccccaata gttatggata atacaattcc
    45121 aaatacaagt acaactatac ttactaatat caacaaataa gttatatttt ttttactcag
    45181 cttagtcaat tatcctacct ccttttccct tttaatcgtc agtataatat catctattaa
    45241 gtattttaat tttaagattt attaaaaata ggtgtgaaaa atgaatatca ttatctcaca
    45301 cctactaagt taagaattac tttgttaatt catttttaac tgattctaat aataactctt
    45361 ttccaattgg attgtatgat tgactgaaaa atggagcagc atcaagtatt gttacattac
    45421 catcttttac tgctcttatt tgagcccaga tagcactatt ttctaaatct tttttatctg
    45481 tttctgtagc aattacaact atatggtctg catctatatc tgttaaacct tccatactta
    45541 ccattggtag tgttattcca tcctgttttg gcatattctt aggtctagct aatttcatat
    45601 catcattgat tagagtacct attccaccat cactaaatac cataaattga cctgaacttg
    45661 ccaacactgg taaataagtt ttttctccat tcttttctat aacttcctta cctaactttg
    45721 tagctttttc atcatacttc tgtagccaac ttttagcttc ttcttctttg tcaaataact
    45781 ttgaaacatc agttaacttg cttctccagt catttgcata atctttcatc ataactacag
    45841 gagctatttc ttttaattgg tcatatattt tttcttgtct ttgactcatt attattaaat
    45901 caggatttac ttctaatata gcttccatat ccatagtatc catcattgag tgcccaacta
    45961 tctttacacc tttaagctct tctcttatgt aacttggtaa tttatcagtt tcatatgagt
    46021 ctacatttgc tgttgcaaca ggcttataac ctgctaataa tagttcttca ctacttcctg
    46081 atatatcaac tattttttta ggatttgatg gtatcttaac ctctccttta acagattgta
    46141 caactcttgt ctctgattta tctttatcct ctgtattctt atctgaacat gctgtaacaa
    46201 gtactaacgt agttataata gatataaata ttgcaagtga ttttattttt ttcatgatta
    46261 cttctcctac ttgtttatta tgcttacatg atattgatta tcataagcac atatttatta
    46321 tagcattttt ctatttttag tcaatattat tttgtaaaag gataaaaatt cctaattaat
    46381 cttaattata tatagcttag ataaggtttt cttatattaa acagtatttt ttttaagaat
    46441 tggacacaaa tacaatgact tttcagttaa acaatgataa aatgcaattt atagataagg
    46501 aatttagtag ggaggattca aaacatggta catttagtat attgtgataa tgcaggaaaa
    46561 aaaggagaaa aggtcttaga taaaatctta gctggaacaa aaacaatggt tattagaggt
    46621 gctgctggta gaaaaatacc acatagtaga gtatttgaag atgagttact ttattttatg
    46681 gaaaaaggaa ctgcaaaaat atctgcaaaa gccactgtta aaaaggtaaa aaactatgtt
    46741 aaattaacag aagatgaaat ttctaaaatt ttaaatgaaa atcaaccaaa attaaattta
    46801 tctgaaaagc aaaaagttcg ttggcataaa aaatgtttat gcttagttga atttgaaaat
    46861 gttgaagaaa taacacctct tgattttgac catcaaggaa atatggatga ttggcttatt
    46921 gttgaaaaaa ttgaagatgt agttgttggt actagtatac cttacaatta tgagaagtct
    46981 aaattttaaa gtatcaataa cataatacta tattgctaaa ctctacttaa ataaaaaaag
    47041 agtgcattta ataattataa aaattatttt tatacactct tttttaataa taattttaaa
    47101 ttacttactt tctaatcttt catatacatc tataaattct tctgctaatt gttgaaaatt
    47161 catagctgtc attaaatggt cttgtgcatg aataagtata acacttattt cagttttatt
    47221 accattagct tcattttgta tcaattctgt ttggaattta tgagctttat gaattgattc
    47281 tttcgacttt tcaatacatt ctctagcttt atctatattc ccgctctttg cttcttttat
    47341 tgcttcaaat gctagccctt tcgcatcacc tgcaaatcca attattccaa aagatatctc
    47401 tatcatcttc tcatccattt attcgacctc ctaaatatct ctatagcttg atatgactaa
    47461 tccattcttt tctaaaaatt ctttgacttt tttagatgta agtatcttgt gctctttcgt
    47521 tctatcaata gcataagatg tagaatttaa aatataatca tctaaaaaag ctgggtgaga
    47581 cataatatcc actacatcat acttcattat ttcgtctata ttttttataa aatattcttc
    47641 acttacattt tccttataaa aactatctat taaaggaact actttagaat actctaaatt
    47701 atattcaaat ccacctctta tcggaagatt atacttggtt acaatcttct ctattactga
    47761 ctttaaactt actaaagtat ggatatgatg gtgactatct aaatgagata tatctattcc
    47821 aagccctttt accctatcta tttgagcaca aagttctcta taaatctcat cacaatccat
    47881 tttttcaata atttcgtctg taatcctcct aataaaaaaa ccgtctttat caacaatagt
    47941 ttttaagtta gataataatg gtctaccaca acttaaagtc atatgaactc cacaatttaa
    48001 agttttattt tctttaagta agcctactcc atgttctacc ccaggcatat ttgccatcat
    48061 agaagtagac ctaactatac cattattatg agctgaaatt attccatagt tcacagcttc
    48121 acaatatcca aaatcatctg catttattat aattttagtc ataccataac ctactttcta
    48181 tagacaacta tctattaaat ctaggaagat aatctttatg agcttccaac atttcgtcta
    48241 atatagtttt tgctaagtca tcagatggaa tcaatgggtt tatacaaagt gccaaaagag
    48301 cagattcata atcgccatat acagctgctt tagctgccaa tacttcaaat gatttgattt
    48361 gacttactaa tccatgcaca gaatctggta aatatcctat acttattggt tttgggccat
    48421 tttttgttat tacactactt acttctaccg cttgttcatc tttaaaatct cttatagaac
    48481 ccttatttaa tgtattaact acttggatat cttttttgtc attgtatata gaacttatta
    48541 aattacaagc agcatcacta tagtaagccc ctcctctttt ttcaagttga ggtggtttta
    48601 catctaattt ttcatcctta tataattcaa ataattgttc ttccaattct ttaactactt
    48661 gacctctagc ttttccctct ttaaactctc tcaactcatc ctcaagcatt tctttagttt
    48721 tatagtagta tctatgatat ggacaaggta ttgcacccaa agattttaca aattcagcat
    48781 taaaatcaat tgcctttata ttttgcatac ttatatctgc tttgacaaat ttatcaattg
    48841 cttcttttgt aacatcttct ccatctaaag atacatttag accataaacc atatgattaa
    48901 gacctgcaaa atccatactt attctgtcac tttctacatt aaatagtttg gcaacatcat
    48961 tttttaaatg aattggcacg ttgcatagac ctatatatct tctaaaatta gtatatttga
    49021 atacagcctc tgttattatt cctgttggat ttgtaaaatt caccatccat gcatttggac
    49081 ataattcttc cacatctttt attatatcaa atataactgg tattgtgcga agggctttaa
    49141 ataaacctcc agcaccatta gtttcctgcc ccataactcc atgagataaa ggaatagttt
    49201 catcttttat tctcgcatct aaaagaccta ctctaagttg tgttgtcaca aagtctgcat
    49261 ctcttagagc ttctcttcta tctaaagtaa gatttatttt catatctact ccagcttttt
    49321 ttaccatcct cttagctaga tttccaacta tctctaattt ttcttttcca gcttctatat
    49381 ctacaagcca taattccttt acaggtaact cttcatatct atttataaaa ccctctacaa
    49441 gctcaggagt ataacttgaa cctcctccaa ttgtaactat ttttagtccc tttttcatct
    49501 cattatacca tccttaccta taatttaata tactctacaa aaccccatac atttatttaa
    49561 aactctatac atttatttac cgaaataaaa ctacctagtt gttaattttc aatttattag
    49621 cttccatttt ttcagacgct atgacaaatg gaatatatat taatattgat aatattaaat
    49681 taaatagtgc taaagctcca ccagtccagt cacctgtagc cattgctcca cctaatatag
    49741 gaggtgttac ccaaggtatt ttaggtaaaa ttacaggtgc tactaatcca aaatctattg
    49801 ctagatatga tacagcacta catatcactg gtgcaagtac aaatggaatc ataaatatag
    49861 gatttaaaac tattggaagt ccgaatatca atggttctcc tatattaaat attgcaggtg
    49921 gaccacctaa tactatcatc tctttacgtc ttcttccagc tattaataaa gctactatta
    49981 atcccaatac cattccagaa ccacctaaat atacaaatgc atcaaagaat gcacctgcaa
    50041 gtacatggta tccttccgtt gctcctgctt gagccaaggc agcattttct ccacctaatt
    50101 tcataagtat agtttctgta aaaggaagtg ctatatttgc accatgaagt ccaacagtcc
    50161 aaagtatatg aattataaat gcaataagca ttgtagaacc tagactatca gctacatttg
    50221 atagcggtgc tcctaaataa gtatttaaaa tatctgttaa gaaacttcca ttagaaagca
    50281 tttttataaa tattcctatt acagtaaata tcattatagt taacattcct ggtattaact
    50341 ttgcaaatga tcttgaaact gctggtggaa ctccatctgg catttttata gttaatttct
    50401 ttaccttaga taatcttaca aatatctcag ttgataataa tcctattaat atagaagaga
    50461 ataaagctgc tgtacctaag taggtttgtt gtatcattcc ccatccttca actactgtag
    50521 ttcctccctc aggaactatt ttaccaattt gtggagccat tataaaaaag atagataaag
    50581 ctataagccc agattgtaac ccatcactct cataagattt tgctagaaaa taagcaacac
    50641 ctattactaa aaatactgcc attgtaccta ttgctcccca ccaaaggtcg cctccaaatg
    50701 tggtccagtt ttctccaaat atacttgcca tcaaattttt gtatacttcc aatggtaagt
    50761 tatttatcaa tgttcccaat gcacctacca tagttatagg tatcattact ataaatgcat
    50821 ctcttactgc tactaagtgc ctttgagctc ctattttagc agctacaggc actatatatt
    50881 tatccataaa tgacatgaat ttttccattt tacatcctcc agtacaactt tattttgaac
    50941 tatttaactc tacagctcta tctaacacag cttttccatt acatcttcca taatccatca
    51001 tatttataac ttctactgga atattatatg gttttgccat ttcagttgct tttcctaata
    51061 catatctaac ttgaggccct aaaagtaaga catcacaatt ttctatttca ttttttaagt
    51121 tcacttctga tatagcccat atttttgctt ctataccgtt ttcctttgct gcatcctcca
    51181 tttttgtaac taataaacta gttgacattc ctgctgaaca agctaacatt atttttatca
    51241 ttttttcccc tccaaattag attcattaaa tattttttaa gtcataagtt ttttaaacta
    51301 tacatttaaa atatgttttt ctattaattt tttcttaatg tatatatctt atttttaaat
    51361 gtatatacat ttaattcttg atattattat ataccaaatg tatatacatt tcaagaaaac
    51421 tttttcattt tatttaaatt ttattcgaca acagcattca aagttaatgt atatccatag
    51481 tgatatgtgt gtgagtactc aaaaatctca ctattttgta acttacaaat ttggcttata
    51541 tataaaagtg gctctggttc ttctaatttt agattatcca tacactcttc attcgatatt
    51601 acagcttgta cttctctctc tgacatggct atcttgtatc cacacacttc ttcaacaaaa
    51661 ttataaagag aattttcaca atgagtctta tttaaatttg gaaataactt aactggcata
    51721 taagtaatca tatatgaaac tcttgcatca ttggctaatc ttactctttt tatttcccaa
    51781 acattttctt ctaaacttat attcaactta cttgataaat tttcatctgc ctgaactatt
    51841 tcaagagata ccaatatatt agatacttta tagcctttac tttccatctc tttagtaaat
    51901 ccacttacag acgatatatt atcatatata ttatttgcaa taactatact acctacacct
    51961 ctttgtctag ttatatagcc ttctttaact agattattaa gtgcagacct tacagtcatt
    52021 ctagttacat taaattcttc actcagctgt ttttcagaag ggattaaatc cccttctttc
    52081 aaactgtctg aatttattaa ctctctaaca tgattttcta taactttata aattggctct
    52141 ttcatttaat tcactcctta ttaaatcttt tatataataa gataatttta tatacaaaca
    52201 aagaaaatgt ctatacattt aagataattt aaattttatt cagaaatctt gtacaacttt
    52261 ccgagtttta ataaagatac aaatagactt atcattaata taccttttaa tatacttgat
    52321 aaggttatac tccaccatac accatttaga cccaacattt ctggtctaga tataaagtaa
    52381 gccaatggta ctcttgcacc agtcagtata gtaattataa tagaaggtat ataggttctc
    52441 cctaatcctt tgaaagctcc tgttgttatt atttctaaac acataaaaaa ttgagaatag
    52501 cctaatattt taagataaat tgctcctttt tctattgcct cactttcatc tataaaaata
    52561 gaaaatatac tctctcctgc aaatactaat actaaagtag ttattatacc aagtacagaa
    52621 gatacagtta tagctatttt gcaaccttta tttattctag aatacttctt ggcaccataa
    52681 ttttgtccaa caaaactgcc taatgcaact gatagccctt cagccgtcat ccaggaaatt
    52741 gcttctattt gtgagcctac tttttgtact gcaacagcca caggccccca tgatgctact
    52801 attactccta atagcattga gaatactgta aacataccac tttgtattgc tataggtaat
    52861 cccaatttat acagaacttt ataatattta gtctctattt ctttaaatag tcttaattta
    52921 aaatattctt ctttactttt aactattata tatataaaac atgtagtaac tactatctga
    52981 gcaaatacag ttgcaatagc agctcctgca acaccaagtt ttggagcaaa tccccatcca
    53041 aaaattaata tagggtcaag tataatatta gttattaatc ctactgtatt aatacgaaaa
    53101 ggagttttac tatttccaag accattgaaa attgcagtaa atactggatt aataaaataa
    53161 aataccatac ttagagctac tattatcaaa tactgtctag acatggttat aacttctaag
    53221 tctcctaatc taaaaaaacc tatcaattgt ttattaagta ctattaaaga aattgtatat
    53281 attattgcta gtataatatt tatttctatt gctgacttca tatatgattt agtagtgctt
    53341 atattatttg caccaatact ttgtgctact tttatctctc cacctacttt tgaaatcata
    53401 ataaatgcca ttgcaagcca tggaaaaaaa ccagcggttc caactgcagc tactgcttta
    53461 cttccggctt taccaaccca tatcatatct atcatgttat accccatctg tataaatgaa
    53521 gtccccatta ttggaagtga tagcttaagt aatttttctg taattcttcc ttctgttaaa
    53581 ttaagtctgt ctttcatttt ccacctcttt tatattaaat ttatttgctt atatagctag
    53641 attaatcatt ttatttgatt gagttcacta tccttcaatt tatattatca tatctcagga
    53701 ttgcatctca atcatactta tgtttaagat acagtatttt acctatctat gataaaatta
    53761 atacttatga atataaatct agccatttca tcaatacata ttctaaccct taacttaact
    53821 tcaattaagt atacatatcg taaccaatta gaatatttta tacggtatct tccattaata
    53881 aacaaccaat atcaatgatt tatatataat tttatttata cataaaatag tatactataa
    53941 taataaaaaa actatatttg aatactttaa gcatgtttac taattgtaat ttccacacaa
    54001 acttgataat atatgaatat attatggtga aatttataga tatatattaa ttatggggag
    54061 attgtgggag gttcttttca caagacattt aagctatgaa aataaataaa aaattcaata
    54121 gagttgatat gcaggtttca atacttactg caattattgt aataatatct tcctcatgtg
    54181 tatatttttt taattataca ctaacttata agagcatgat atactcttta agtgagaggt
    54241 caaaacatat ctatgaatat gtagaaagaa atattgataa aaataccttt actgaaatta
    54301 attctaaaga agaccaatca aaaaagtctt ataaaagttc taaaatcctt ttagaatctg
    54361 taaaaaatac tactggagta atgtatctat atactgctaa aaaaacaaaa gatggatcac
    54421 tagtatatgt tgttgatggt ttaaattcat ctaggagtga ttttagaaat gctggtgatt
    54481 tgatagaaaa agagatttgg ggagacctta acaaagcatt agataatcat atattgttac
    54541 ctaaaaagat taaatcaaca tcttggggat acatatttat atcgtatttt cctattcaca
    54601 atgatgttgg taaggttgtt ggagtaatag gaattgaatt tgaagcaaaa catcaataca
    54661 atacatttaa atttataagt atagttacac caataatagc attattaact tgtctaatat
    54721 cagcattgat tgcagtgatt ctatttaaaa gaatatctaa tcctacatat actgattttg
    54781 ctaatacaga ttatttaaca ggcctaaaaa atagaaatgc ttttgaaata gatatgaata
    54841 acttaaacaa ttcaaatcta aagaatctaa tatctatcat atcaatagat ttagatggtt
    54901 taaaaaagat taatgataaa tttggccatc agacaggaga cttatatatt aagcaagcaa
    54961 gtaaaattat acaatatgta ataaataaaa aatatatagt ttatcgtatt ggaggtgatg
    55021 aatacataat tattctaaaa aatttatctc acaaagaaat aaataatatt ataaataata
    55081 ttaatttaaa aatagttgaa gaaaactcaa ctaatgaatt aaaattatca atgtctattg
    55141 gatatgctat ttttgatgaa aaagtagatg tttctttatt tgatacatat cgtcgtgcag
    55201 attctcaaat gtatgataac aaaaggaaaa ttaataaaca atatcaataa taaatttaaa
    55261 aagtctattc tttaaataat aaatcataag aatagacttt ttaaatttgt gttttataag
    55321 ataaattatt taattaaagt ttgttctttt ttctaaacga ttctttataa attcatatat
    55381 tactttcact aatatatttg tgactaatat taacacagct agtgctgctg cctgtgcagt
    55441 actcccctta tcatctagtt gtacaattga tattgcagct acttttgaac ttgcagtata
    55501 tataaaaact agtgctgata ttgtcaccat ggagtttagg aaaaagtaca taaagttctc
    55561 taaaactgct ggcaaacaaa gtggtatagt tacgttctta agaattgatg cgctgtttat
    55621 tcccattgat ttagctacca tgtccaattc tttatctact ttcttaatag cagtagtagc
    55681 tgttataaat gctactgaaa agaaatgaac tatattacat ataaccatta taagtaatgt
    55741 tccatataat ccattaaaca aattcttaat gtatattgta tccataaaat taaactctaa
    55801 tttattaaaa aataatacat aagctatacc taaaactaat cctggcaatg ccataggcaa
    55861 tgtacttaaa aaatacccaa atgattttaa atatggagct ttttctgttt tttcattcaa
    55921 atatgcaaat aagaaaacaa agctcgtccc tagaatagct gtcaatagtg acatttttat
    55981 tgaatttata aatggtttaa tcccatcaat actgtttttc atagaaaaat gttctagtgt
    56041 cagtcttaaa tcatatggcc aaactgatat taatgaagat aagattacag ttaacattac
    56101 agctattata ccaaatgcaa taattcctac aacccctcct aaaatactat ctcttaactt
    56161 attagtttta accttatatg gaattgactt tgaagttata tatgaatttt gatttttttc
    56221 aattttttta gttactataa acgatattat tgcaggtatt aaaagtaata ttgatacagt
    56281 tgctcccatt ggcatattct gttgccctat aatttgctta tatacatcta ttgataatac
    56341 attaaactct cctcctatca cctttggagc tccaaaatct gtaaaacata atgtaaacga
    56401 tacgaatgca gaacttatta aagagtattt tatacttggg attgttatgc ttataaattc
    56461 tcttatcttg cttatcccca tagtattact agcttcatat agtctataat cggttgaact
    56521 tagagatata taaagtattt gaaatgattg aggaaataca tatataattt gtgccaatat
    56581 tattcccact gctccatata ttggaacatg cactccaagt aaattagtta ccaaaccttg
    56641 atttccaaat aaatatacta gacctattgc atgcatcatt gttggagcaa acataggaaa
    56701 catagctaat gatttaaaaa aacctttaaa tttaatcttt gttctagtta atgcatatgc
    56761 atatactaat gcaagtgtta gtgatattac agttgatata actgatacaa atactgtatt
    56821 ttttagagaa tttaatagag attcagaagc caagtattct tgaaagtttt gtaatcctac
    56881 aaagactcca tctttatcta aaaaagcctg tacaaataga tatattatag gtgctaataa
    56941 aaatattact aaagacataa ctaatactgt aagcatacat ttttttatat ctaaattcat
    57001 ttttgattta agacttatac ttttagaact tatagcatta ttattcatat acttatgctc
    57061 ctttaacttt tggatacttt aaatagtatt tttcgtctat acttattttt acaaggtcac
    57121 cttctactaa atttaaatta acccactctt ttatagaaac atcacttatt atgaaatttt
    57181 catttaattt atcttttatt tcaactctca ataaattccc tctaaactct atatttgata
    57241 ttatcccttg gtagttttct tttgtcgatt tctctatttg aacatattct ggtcttacag
    57301 ttaatataga atctccatta tcaaaacagt ttgtatctcc tataaattga gctgtaaata
    57361 ggttttgagg attttggtat atttcttctg gagtccctat ttgcattata tctcctccat
    57421 ttagaatagc tattttatct gccatagtta tagcttcttc ttggtcatgc gttaccatta
    57481 ttgtcgttat attaagttct ttttgtaatc ttttaatgtc cattctaagc ttgtgtctaa
    57541 cctttgcatc taatgcggac attggttcat ctaaaagtaa aaactttggt tcaagagcta
    57601 atgctcttgc tattgcaatc ctctgttgtt gcccacctga taatgcttta ggatatttat
    57661 gagcttcatt agtcaatcca actgtttcaa gtacttcctt aactttatta tctatttttt
    57721 cttttgaaac ttttctctct tttagtggaa aagctatatt gttataagca gtcatattcg
    57781 gaaataatgc atatgattga aatactatac caaaacctct ctttgatggc tctaaatttg
    57841 taatatcttt atcctggaga attatagttc cactatttac atcttcaaga cctgctatta
    57901 ttctaagtaa tgtagtttta ccacatccac taggtccgag taaacataga aattcccctt
    57961 cttcaatatc caaactaata ttatttaaaa cctttttttg gtcataactt ttaaacacat
    58021 tatttatttt taagtaactc atatcttatc tctccttata tagttatttt tttattttaa
    58081 attttatatc ctactttttc ttctaaaatt ctttcatcta aattattaat ttaaacctta
    58141 cttactttca gattttgaac cgtattttga ttcccaagtt ttaagtactg tacttctgtt
    58201 tttggcagca gagtttaaat caacttcttt tataagctgt tcaaatggtt gtttagaata
    58261 accttttgga actggattat ctgtctttat ggaagtaact gctacttcat gtgcatatct
    58321 atccatagct gaatcactta ttgcccaatc taaaaatagc tttgcttctt tttttatatt
    58381 atctttttta actaaggcat ttgcttctaa gtcccaacct gaaccttcct ttggaaatac
    58441 aacctctata ggttctccac tagataattg ttgtgtagct ctatatccaa gtgtaatacc
    58501 tattggatac tctccagagc cagctaactt cgcaggtttt gaacccgagt gtgtatatgt
    58561 ggctatattt ttatgtaatt tatccatgta attgtaagca tctttttcac ccatcatttg
    58621 aataagccct gatactgtaa gataacccgt tccagatgat gctggatttg gcattgttat
    58681 aagtccttta tattctggtt ttattaaatc ttcataactt tttggaatat ctatacctag
    58741 tttcttaagt tccttataat taactactat tgctgtctct gggacactca ttcctaccca
    58801 agatacatca tcttcagtat ctttaaattt tttatcaact ttctcataat ttttaggctt
    58861 atatgcttca agtgcaccat ctttttttag ctctatcatg ttcattgctg ataatcccca
    58921 tataatatct gcttgtgggt tatctttttc tgctaatagt tttgaagcta ttacaccatg
    58981 agaatccata actatctcta catctatatt gggatactct tctctaaaac cttccatata
    59041 ataagctatc tgctcttcct ctagtgctgc atatattgta agtttattat ttccttttcc
    59101 ttgagtagtt tgtggtgttg ttgatatgca acttgtcata aatgtaatca ctacaatgca
    59161 cagacaagta aatataaatt ctttcatatc ttcccccctt tgtgtttttt ccttttttta
    59221 tttgtttttc attgtttttg cttatgttta tataatacac ctaatttgtt aatataaagt
    59281 taagtgtaaa ttaacagttc gttaattttt agaaattttt gttaaatata ttatttttag
    59341 ttaaatatag tctgttttta aacaatatat taatttttat agtatctaca ttttaattta
    59401 aacataaaaa ataagtctaa cctctataaa gtagaatgtt agacttattt ttataagtat
    59461 ttaattatac aaccaaatca ttttttttct tttcttcaag tgctttttta agcaccatat
    59521 ccttaacctt cataagtcta gtagtacttg ctctctcatt ttcttcaagc ttcatagcta
    59581 tatacttaat agtctcaatg taatttggta tcattacatt ttcaagagca ttaacacgtc
    59641 tacgtgtctt ttctatctct tgtgcaagaa gctgtgcact tttttcactt tctgcaagtc
    59701 ttaaaagtgg ttgcatagca tctgagaaag cttccatagc agaatctaat tcacctgatg
    59761 taaaagcaag accataagga taaatatcac tttgattgtt ttcagtttta aagtcaaaca
    59821 caggaacatc aacactcatt atatttctcg tagaaacatc tactgaaact gattgctttg
    59881 gcatcataag tgctgaaccc aaatactcct gactcataac tgctcttgcg attataaaat
    59941 ttttataagc agtatcaaga gcattttctg cttcttcacg caatcgctta ttttctctta
    60001 caatctcaag aaattgtttc ataagttcat caagtttatc tttaagaagc ttatgacctc
    60061 ttgtagcagt tttaaggagt ttcttaagtc tagtcatttc catacgtgtt ggatttatat
    60121 ttaatctagc cacagatatc actccttagg catatatttt tcaaaatatt catcacggat
    60181 acgtttaagt tcactttttg gtaacatact aagaagcttc catccgattt ctaatgtctg
    60241 ctcaatagtt ctatcagttc taaatccttg tgaaacatat tctttctcaa attcatctgc
    60301 aaacttagca tacattaaat caatctcaga aagtgcagat tcaccaagta tagccataag
    60361 ttcttttgca tccttacctc ttgaataagc tgcaaaaagc tggttcattg tatctgcatg
    60421 gtcttcacga gtcttacctt taccaatacc tttatctttt agacgagaaa gtgatggtaa
    60481 aacatctata ggaggctgta tatctttttt ataaagttca cggctaagta taatttgccc
    60541 ttctgtaatg tatcctgtaa ggtcaggaat tggatgtgtc ttatcatcct caggcattgt
    60601 aagtattgga atcatagtta tagacccttc atgccctttc atttttcctg ctctttcata
    60661 catagtagca aggtcagtat aaagatatcc tggatatcca cgacgtcctg gaacttcttt
    60721 tttagctgct gaaacttcac gcaatgcctc tgcatagttt gtaatatccg ttattataac
    60781 aagtacatgc atatcttgct cgaaagcaag gtattctgct gctgtaagtg ccattctagg
    60841 tgtagataca cgctctacag ctgggtcatt tgcaaggttt acaaacacta cagaacggtc
    60901 gattgcacca gttgctttaa aatcgcttat aaaaaattca gcatcttcaa aagttatacc
    60961 aactgcagca aatacaacgg cgaacttaga atcagttcca cgtacttttg cctgtcttgc
    61021 aatctgaact gcaagattgg catgtggcaa accagaccct gagaatatag gaagtttttg
    61081 ccctctaacc aatgtattaa gtccatctat agcagagact ccagtttgta taaactcggc
    61141 cggataatca cgtgctgctg gatttattgg agctccattt atatcaagtc ttttatctgg
    61201 tataatttct ggacctccat caataggtct acccattcca ctaaaaacac gacctaatat
    61261 atctggtgaa actccaaagt caagactctt tcctaaaaaa cgaactttac tttcagcaag
    61321 gtttatacct gttgagcttt cgaaaagctg aacaagtgca gtatctccat ttacctctag
    61381 aactttgcaa cggcgaattt ctccatttga aagttcaatt tctccaagtt catcaaattt
    61441 tacaccttct acgccgttta ttaacataag aggaccggct acctcttgta ttgacttata
    61501 ttcctttatc atagttcttc agcccccctc tttttaataa ggtctgcaag ctcgttgtct
    61561 atttcatctt caattgaatc gtaagctgca tctatatcgc cttcttctac atacttagca
    61621 cgaccaatct tttcaagaac tgaaagcttg ataatatcgt ttatagtaac attttgcttg
    61681 atagcatctt gtgctgactt atagaatttt aatataagtc ccatcattct atattgttta
    61741 tgaagtgatg tataagtatc aacttcatgg aaagagtttt gatgaaggaa gtcttctctt
    61801 atagaacgag taacctctag tatcaatcta tctccatctg aaagtgaatc aaccccaacc
    61861 aattgaacta tttcttgaag ttcagattca acttgtaaaa gtttcatagc ttgagctctt
    61921 tgagctgaga aattatcatt tacattttta tctgcccata catcaacttt ttcctgatag
    61981 agtgaataac tagtcaacca gttaattgct gggaaatgac gtttatatgc taaagatgca
    62041 tcaagacccc agaatacttt tactatacga agagttgctt ggctgacagg ttctgatgta
    62101 tcaccaccag gaggagaaac tgcaccaatt gctgtaagtg ttccttctct ttcatccata
    62161 cctagacaat ttacctttcc tgctctctca tagaattgag caagacgcga acctaagtat
    62221 gcaggataac cttcttcacc aggcatctcc tctaaacgac cactcatctc tctaagagcc
    62281 tcagcccatc ttgatgtaga gtctgccata agtgcaacac tatatcccat atctctaaaa
    62341 tattcagcta ttgtaatacc agtgtatata gaagcttcac gtgcagcaac cggcatatct
    62401 gatgtgtttg ctataagcac agttctttgc ataagtgact cgcctgttct tgggtctttt
    62461 aattcaggaa attcaagaag aacatctgtc atttcatttc cacgctcgcc acagcctata
    62521 tatacaacta tatctgcatc tgcccattta gcaagctgat gctgtgtaac agtttttcca
    62581 cttccaaaag gtcccggtat agctgctacc ccaccttttg tgattgggaa aaatgtatct
    62641 ataactcttt gacctgtaac aagaagtgaa tctggtgttt tcttttctct atatggtctt
    62701 tcttttctaa ctggccattt ttgcatcata gttacaggta tatcattacc tttttcatct
    62761 gtaataacac aaactgtatc ttcaacagta aattcaccag aatatatttc ttttatagta
    62821 cccttaactc cataaggaac cataatttta cattctacta ctgctgtttc ttgaacgcca
    62881 ccaattatat ctcctgctac aaccttatca ccaacagatt ttttaggttt aaattcccac
    62941 ttagttgttc tatcaagtga agatacttca acacctttag ttatattagt acctgaaata
    63001 tcatacattt tttcaagtgg acgttgaata ccatcataaa tagttgaaat aagacctggt
    63061 ccaagttcaa cactcatagg cattccaaga gaaactactt cttcccctgg tcctagacca
    63121 gaagtttcct cataaacctg tatagaagct ttatctccat gcatttctat aatctcgcct
    63181 ataagatgtt tatctgaaac tcttacgacg tcaaacatat tcgcatctct catgccctcc
    63241 gctacaacaa gcggtcctga cacctttaca attgtgcctg ttttcatatt ctctcacctg
    63301 caatcatata ctttatcaaa atttaaatat tccctcctat gttttattag cacatatatt
    63361 tagcaccaat aaaatttgag attgtctttt attcaacttt catctattct ttaaataata
    63421 tatctgcacc tatagcacgt ttactagatt ctcttacttc attcatacct aatcccatac
    63481 ttcctccaat acctggaata actataatgg caggaagttg gtaatctttg tattttgcta
    63541 ttgattcttt tgcaagcaat gatgcctgtt ctgtaatata aattatcgca tattcatctt
    63601 caaccaactt atgtatactt tttttaattt cgtcactatc ataggctggg aagatatcta
    63661 ttccaagagc taaaaatccc atgatgctat ctttatctcc aactactcct accttataca
    63721 taagcatccc ttagcctttc ttttatagta tctgcgtcta tattattaag cttactagtc
    63781 aaaataattc taattgtttt tatctctgat tctttagcat ataaatatgc aattagtggt
    63841 tctaatgtaa gaggcttaaa ttttgctcct ctaacatatt ccataagata gtcatcacaa
    63901 agtttttcaa agacagtaaa accactatcc atgccatttt tacagacatc agagtaagaa
    63961 gtagatttaa aacatgatgc tggagtatct gaggaaaaag cttctaagaa tttttcctta
    64021 tcaagtgagc cacctgaaac aaacacattc ataaacatat caaaatcttt cttcatattt
    64081 ttgactctta taaaactctt tagatttgtt aaatcacaaa ctttcataac ataatctatt
    64141 acaaatttgt tttggctttc tttagcagtt tctttcatac tggtaaaggt tgctttatct
    64201 agaacaatat caaccatctg gccattttgt gtcttattat aaacatcaaa tgcctctaat
    64261 atagctgatg acattatctt aggtaaatca ctaaaactac gatttgctaa agattctcta
    64321 agcttaataa gaggaattgt acctccatca attaaatatt tctcaccatc tacaccagaa
    64381 atttcttctt taatcagcac ttttaaattg tgatagtcat ttttataaag aaatacatca
    64441 acaaattttt cttcaggagc tagactttta agaatttcat atgtctttga taattcttga
    64501 gtcaaaatat tctcaaaatt atgtatatta ttatttgatg tatcagcata acctgcctca
    64561 gctataattc ttaaagagtc ttcagggctt ttggcttctg ccatttgaat aaacatttgt
    64621 ctgttaagaa gctgtttttc aagcactctt attcgtgcaa cggcataggg ataagttttt
    64681 tcttctgcca ttttttaacc cctccttaat taaacaaaat ttctgctgca atttgttcaa
    64741 tatattcatg ctctactgca attatggctt caaatgaata attgtactca atgtcacctt
    64801 ttttaactat gaaacctcca gtaatatctc tagtttcatc agacacttta atgccttttt
    64861 ttgatagcac atcttttaat gtttttttat cttttttaga taatactatc tctgaatcat
    64921 ctgtacaatt tgatttttca atcatgttta gtataatctc ttcatattca ttatctttaa
    64981 gatttaaaag tttgttttta gcttctaaaa ttacctcttc taaaatctct tgtttttttg
    65041 ataatatttg ctttttagcc tccatataag ctcctgatat ttccttagaa gccgcttttt
    65101 ctgcttctgc ctctgcaagc tttgtatagg aagccatttc cttttcagct ttttcattag
    65161 ctgaatttac ttttaaatct gcttcacttt tagctttatc caatatttct tgtgcttctt
    65221 gtttggcatc agctataatt ctgtcaatca ttttttgttc attacccata ggagtgcttc
    65281 ctccttttca ttttttttac ttatgaatta taatttataa ttaaccaatt gcaattccat
    65341 tgtaagctaa gaaagaaaca agtagtccta aaagagcata tgtttcaact attgctgcaa
    65401 atgttatagc tttaccaagt tcttcaggtc tttttgcaac tattccaact cctgctgctg
    65461 ctgctttacc ttgtgctata cctgatacta aaccaactaa accaattgga agtcctgcca
    65521 taagaagttg taaaccttga gctgatgttg gtattgcatc tccaccaata atccctgctt
    65581 ttgataaaat aaggaaagct atgataaatc catacagacc ttgtgtacca ggaagaagtt
    65641 gtaaaactag aagttgaccg aatttactag ggtcttctgt tacaacacct gctgcggctt
    65701 gacctgctat tgaagtacct ttagcagaac ccatacctgc aaataatgct gctatagcag
    65761 ctcctgatat tgccaaaaat tgaccatttc ctaacgcgtt taaaaattcc atatttacat
    65821 ctccttttta ttaatgcttg tatattttgt tttatactta aacggaacaa aaggaactcc
    65881 tccgccttca taaaacttat tgaaaaattc tacatactgt aacctacttg tatgaacata
    65941 tgcacctagt gcatttataa gaaggtttat tgtgtgtcct acaacaccaa ttacaactgc
    66001 aagtatcgga ccagctatag ctcctaaaag attgataact tgtgctataa ctcctgttgt
    66061 taaacaaagc gccataattc ttgtataaga taatatatca gcaaaataac ttgttatacc
    66121 atagagactt gaaaatcctt taaaaagctt aacaggaata cctttaaagc ttcttccttg
    66181 agtaagtaca agacctatag cacctataat tgctaaatat tttcctactt ctgaaaatac
    66241 acctatgtcc cctgcaacaa aaggtattat aagtagacat acacctgtta tacacaaata
    66301 ccaaaaacct atgtcaaaga ttgcatctat tacctttcca cttcttatta atgtatatgc
    66361 ttttattccc aaacctacat atatatggat aataccgaac agtaacgaca ttcccataag
    66421 tgtcataaca tcctctaaag gattaattaa tgcttttata ggaattaaat cccccaaaat
    66481 acccccgaat ataagacccc atacagtagt tgaaactcca cagataccaa taagtttaat
    66541 taaatttcct tcaccttttt gtatctttaa tttatataca acaaatccac aaactactgc
    66601 aattattaac ccatatgcgg cgtcacttag catcattcca aagaatataa caaagaagaa
    66661 agttaaaatt gtatttgggt caatatcttt tgtacttgga tagctgtaca tgttagttac
    66721 actttcaaaa ggtgttacta atttattgtt ttcaagcaga attgggaagc cttcttcttt
    66781 acttccttct tcagtctgaa cacaacaatc aaacttttct gtaatttctt taattaattc
    66841 atctgccctt ttgcttggta accaaccatt aagacagaat gttgtttttg ttttgacaag
    66901 tctctctata atcttttttt ggtctctttc tatagtgtaa aaatcatata ggttttcaag
    66961 catgtgtata ctatctgcat gtcttttaat ttcctctgtt ttgttcttag aaacgttttc
    67021 ctgtctaatt atcatttcat tgtatttctt gatagcttgt aacggtgtac cttcttcatt
    67081 tggtaatgaa accactgaaa aattaaattc ctttaaaact tctaaaacat catcaaaagt
    67141 ttcttttaaa gtaattaaat aaacatagtt cattaacttg tcagaattga caatcccaat
    67201 aacactttct ggtatttcat cttctaattt tactcttaaa gcatcaatgt ttgcgcttat
    67261 gggcacagtt ccaagtatag tttttgtata cttagtttcc atattttcaa gaggaatatc
    67321 aaagttcacc catggttcta acatactttt attgttgtta agtaagttta tgttagacct
    67381 tattgtacct atctccttgt gcaaattgtt taactccaga gcttcagcat aaacttgccc
    67441 ttctttttca ctatcaattt tgttaaactc tctttttggt gcaagtaggg attttttttg
    67501 tttcactagt gaagaaacaa tattaattgc ttggtttaca tgagacattt tctgctctag
    67561 cattataact tcagattctt cactatcttt tacaagataa ttttttaatt cctcctcctc
    67621 agtaagaaag gcactatcat caatctgaac aaacccacgg ttcataagta gctttaaaat
    67681 ctggcttttt tgagcttcta agccaacaat agatattttg ttcatattaa ctattgccat
    67741 attatctcac tacctttcca ataaccgctt caatagcctt actttttctt tcttcagcag
    67801 ttttttcaat tttcagacat tcacttttag cattagctaa gattttatca acctctgctc
    67861 tactgtcggt gactgccttc tcaataagag tttcttccat aagctttgct tgttttttta
    67921 catcagcaaa tatgctttca catttgttta cagcatcagc tctgatagac tctgcatcag
    67981 taacagcttt tactttgata ctgtctgctg tctgctctgc ctcaacaatg ctttttatta
    68041 tttcaaaagc catccaaatc acctctctta cctttttact atgtatataa ccaattagat
    68101 ttttttattc taattagatt actacctcat tgttaaagta taaacagcat ttttatataa
    68161 taattaatat ttttcaacgt ttatttctta ataaaacata ttttagaata gtacttgcct
    68221 agatttacat ccttttttga cttactttta gactatgaca tgagtatggt ttttaaatac
    68281 cattattttc aataattata atttaaagcg atatagtttg tcaatagcgt tattttgttt
    68341 taaaattaac gttatgtcga cattttaaat ttttatttta ttttttttat aattttgatt
    68401 taatttatta catataaaag ttttttatat tctttttcaa cctctaaccc ttgaagttta
    68461 ttgttttttt tgaattttta gaaatatctc gcactatttt atctaacttt tataaatcat
    68521 caagctatat cgatttttgt caccttattt ttaatctaat ttttttatat ctagttagaa
    68581 ataaatcaat atttttaaag attgataaaa ctcacaccta gttctaatag ttttatttta
    68641 aggcaatgta ttaatcttaa gtagataata tcattagtta ctctatatat tcgacaacat
    68701 tataaaaaaa tcctcatacc aatcactcca atcttcaata ggatatgctg ctcctccatt
    68761 tacacttttc agtagattgg atgtatattc ttctcccata gaaaaaagtt cccctactgt
    68821 catatcataa cctctagatg taacaacctt acaaaatgaa tccataacat cacgttgttc
    68881 tcttgttttt ataagttcct ttctaaattc atcatcattc ttagcttctt ctaaaatttt
    68941 agttaatttt tcattcatta tgtatttctc cttttaagta gtctttctgt aaacttcaat
    69001 aagctttata taaaaaggaa gccatcctaa ataaactaag atgacttcgc ttaactgtta
    69061 gcaacacatt tactagtata aaataattgg tgtacctggt tctatatttt catatatttt
    69121 ctttgcctta gaaaaaggtg tatttacaca tccatgtgaa cctgaagact tatatatacc
    69181 tccgccaaaa gaatttctcc aagtagcatc atgaatgcct atgttcccat taaatggaag
    69241 ccaataactt acaggtgaac tgtaaccttg accagttaat gaaacatttc tagccttata
    69301 attaagagga tatatacctg atggtgtagc aaatcctcta gctaaatcac ctgttacaac
    69361 gtctgttgat acaagcattt ctccattttt aaagaaccac atatgttggc cagaaagact
    69421 aatctctaca tatgtatttc caatatcatc tttattacga gatacagctt tttgtatgta
    69481 aataggttct cttgtaacat ttttaccagc ttttacaaca tcaactaatg cttcagcttc
    69541 tttcttttta tctatcaacc aaccataaat tccacctgaa attgtaatat ctttacctgt
    69601 ggcagtttta aatggtcttg agtcaccaaa agtactgtat tttttactta aacctcttgt
    69661 atattctacc atagcatcat tatcaaaagt tatgtcataa ttcttttctg agtctacttt
    69721 taaccattta ttaatttcag aaccatctaa agtttcctta cggtcactaa aatcatatgt
    69781 aacgactaca ccaacatact tatctaatgt cttaatagct tgtttcaact tttctgaatc
    69841 ctttgtgttg tttggtgctt cataaacttt actttcatcc agagaaatag aagtattccc
    69901 agaattaatt gagttttgta ctaacttata aaaatcctct tttttcactt tgtttccaag
    69961 tacctctggt actataacat aagcgttttt agtgctatca tacttaggat aagcactctt
    70021 aggttctaca acatttttac tatcaaaaca agataaagca ttaaaccttt tttctagtaa
    70081 atctttatta tatgaaagag ttatcatatt attatactct ttagacttaa atattccacc
    70141 aatccatcca atagcgctct gactatcttt tatcttttga actttatcat ctggtgtaaa
    70201 ttttaaatca atatcttttg cttttatttg ttctttctta ttgtttcttt cctctaagtt
    70261 taaagtatag gaattagtac tagatgttaa caaatcattt acttgctcaa ctgtttttcc
    70321 tgaagccttt acgccattaa tagtcgttcc aaagtaaaaa tgatttctaa aaaagattgc
    70381 cattcctata taagctacaa acaaaacacc tactactata gctatcttaa attttagatt
    70441 tttttgtcca ctttcttgtt ttacctcttt tccatcaatc ataattaaat ccttccttac
    70501 attgtaatta cctatgtacc ttattggttt ttaaacaaaa ccatgtatgc cttattttat
    70561 atacccaaat tactgtatca ttatttatat ttttaaatat atagttattt ccataaaacc
    70621 attttatctt ttagataaaa tgattattat aaatcccccc tttcaaaatc ccttaaacac
    70681 aatctctgct atattaatat attaccatac ttttaataat cgtgggacta tctatctatt
    70741 tttgtaacac taaactactc ttttaaaaaa gaaactaatt ttgtgttagt ttctttatct
    70801 taacttattt ttatattgaa ttttagctta acataacgtt gttatataga ttctatttaa
    70861 ttattttagt ttctatatct tttccatctg catattcttt aagtaattcc ttagcatatc
    70921 caaaatattc ttcaatatca gattcttgac taaaagaaaa tatacaaatt aatatttcat
    70981 ttgcatcttc tgttatcatt gctctttcag aatcactagt tggactccca aatttaccca
    71041 ctgaatcaga caatatagga agattttcta tatttattaa ttctttccca atacccttat
    71101 actgttctcc ttcatctcct acagtaaaac atactggtga atgtaatttg cttacattat
    71161 atgtacctac tggatataat gattttattg atattaaatt gtttatttct actatattat
    71221 ttattgtata aagacccttc ccttgaataa ttcttctaac caatgcttct gaagatgttc
    71281 tatatctact tggatttttt ccaagctctt tataagcatt tcttgcatct ttaattttat
    71341 ctagtttcgt aatgtcttca acttttagac tttgatttat agtatcacaa aactcattta
    71401 tttcattaat taatttttct gagcttttat ttactgctac ttttgcttga atgcaaccca
    71461 gcttagcatt aggccatctt tccttaagtt tgtcatcaat acttacatct atcatactta
    71521 aacaactcct atacactaaa tttttattaa agtttttatc atctatacat tatagtacta
    71581 ttcttttgtt aataacatgt ttattaacaa aataaattta tttttaatat aatttttata
    71641 aaatacaat
//
LOCUS       DAEORM030000017        65870 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.017, whole genome shotgun sequence.
ACCESSION   DAEORM030000017 DAEORM030000000
VERSION     DAEORM030000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 65870)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 65870)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 65870)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..65870
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.017"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            complement(376..1098)
                     /locus_tag="KRH23_001522"
     CDS             complement(376..1098)
                     /locus_tag="KRH23_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015424 - ABC-type amino acid transporter
                     activity [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HHS5224805.1"
                     /translation="MITIKNLSKSFGDLNVLKNIDLEIAKGEIMVIVGPSGSGKSTLL
                     RCMNLLEIPTGGEIIFEGKNLVDKKTNIDEVRQNIGMVFQNFNLFPHKTILDNITLAP
                     IKLKKMTKEEAEKKAEILLSRVGLLDKKDSYPSQLSGGQKQRIAIARALAMEPDMMLF
                     DEPTSALDPEMVNEVLDVIKELAKEGMTMAIVTHEMGFAKEVADRVIFIDGGSILEDN
                     TPEEVFGNPKHERTKAFLAKVL"
     gene            complement(1157..1834)
                     /locus_tag="KRH23_001523"
     CDS             complement(1157..1834)
                     /locus_tag="KRH23_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HHS5224806.1"
                     /translation="MSLDFSFLSRFGTSFLEGTGVTVSISLVALCFGFIIGIIICMAK
                     ISKSKVLRAISSIYIEVLRGTPLLVQIYIVWFGLPQLGIRFPMLFGIPSEFIASAFAL
                     SVNSGAYVAEILRSGIQSVDNGQMEASRSLGLNYWSTMRYIIIPQAIKNILPSLANEF
                     ITLVKESSIISVIGVVEIMRTADIVKNAAFRALEPLIVAAAIYFVITFTLSRLVGLLE
                     KKLSVSN"
     gene            complement(1862..2677)
                     /locus_tag="KRH23_001524"
     CDS             complement(1862..2677)
                     /locus_tag="KRH23_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HHS5224807.1"
                     /translation="MKVFKKLLSLGLVLGLTLSLVGCSGGGEKTKLEQIKDNGKLVVG
                     TSAEFPPFEFHKVVDGKDSIKGFDIMLAEEFAKELGVKVEIKDMSFDGLIGALNADQV
                     DIVLAGMSPTPEREKSVDFSELYYLSRNAVIVKDADIDKVKTEDDLKKLRVGVQAGSI
                     QEEYVVNTLKMTTTKSLKAIPDLITELKNGNIDAVVTNEAVSLINVKKYDGIKMANTE
                     VGKDVTEGMAAAIKKSDNNKDFIELLNKKIKELQDGKKIEEFLNEASTEAASN"
     misc_binding    complement(2903..3113)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(3496..5562)
                     /locus_tag="KRH23_001525"
     CDS             complement(3496..5562)
                     /locus_tag="KRH23_001525"
                     /EC_number="3.6.4.-"
                     /EC_number="5.6.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HHS5224808.1"
                     /translation="MVELIITTNIDIRKLNENQLEAVEHIDGPCMILAGPGSGKTRVI
                     TYRIANMVVNKNIAPTRILAISFTKASSIEMKNRALNLSDDIRLNKVTYGTFHSVFFK
                     ILRYFERYNLDSIFDEKSKRMTIKAILKSLNIENADDDENIGQVINEISYVKNELMDK
                     NEFNSEVLTKDEFLKVYNLYEEQKSKVNKIDFDDMLIRTYYLLLNNKSALEMVRNVYK
                     YILIDEFQDINKVQFEVLKLICSPLNNIFAVGDEDQSIYGFRGARPDFLLEFEQYFNN
                     TKKIILDINYRSKSEIVHTANRLIDKNKNRYEKIIKCSQGDGGSVTYISPHDSEEEAL
                     YIAREIIDEIQKNYVEYSDFAVIYRTNIQSRALVDVFMDMRIPFVVKDSVITIYDHWA
                     SQDILAYLRIGINPKSNKDWLRIINKPFRYISKDSINMVKDENDFITALINKCNLHPK
                     QVKTINDLEIDLSYLNTLNPKNAISYIRTSLDYDRYVLDYCSNRKIKTNGLVEILNEL
                     ESSATNFNTVTEFLEHIDRVKTELTENNKNKQTEGVIFTTMHSAKGLEFRNVYIIGVN
                     EGTIPHEKSYDICKEEKKEEQLEEERRLMYVAITRAEEKLCISSTLNKYGKKVDKSLF
                     INDIKSPTKKEIDSIGVGDKVYHKKFHEGEIIKKDGIMFTIKFKDRERILDLKTCLLK
                     NIIYTI"
     gene            complement(5639..8668)
                     /locus_tag="KRH23_001526"
     CDS             complement(5639..8668)
                     /locus_tag="KRH23_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HHS5224809.1"
                     /translation="MENNLRKNNSIMKKMIFPLIIVMLIQTSLFCATILWGGTIKKLN
                     DNSFDILNERVINRKNYIQNEMLQRWSNTSETEATINSSVKKVLNEKNALIEDVGNNE
                     EINKDIIKSISNDLIYLLRKNSVTGAFIILSDKNINDKSIDSKGEISRTGLYIRDLDP
                     KFNPNDNSDLLIERGSSDIARSFGISMDSYWEPKFSFKSENEQDGDDFFYKPFRAAID
                     NPNVSSSNLGYWGSKFLLTNAGDRLMTYTVPLIYEDGTVYGVLGIDLSVNYLRELLPY
                     SEINGNKKGNYILGVDRNNDMAFENVISNGYSLKEKFWDGLHSNLEQKESYKNIYKIK
                     NKDNECGNGNIYASVQYLDLYNSNTPFENERWALLGIIEEKSLLSFSKRVEKLVIISI
                     AISLLIGLIGIYIASRLFTKPIVLLANKVRNSNPSKPVNLDKINISEIDELSSAIELL
                     SANVADSSSKLSQIIEMVDMPIGAFELYKNAENVFCTKEFFSVFTTEIKFEEYGYMEK
                     NKFLKKLRGLDKYLQESYETENTYIYKFESKDKKLKWIRMNIFEDELKVLGVVVDVTK
                     EFIEKRKIEYERDFDILTNLLNRRAFHSQIQEKFKNKDELKIAAFIMWDLDNLKYIND
                     TYGHDAGDEYIRCAADILKKFISWNGIVSRLSGDEFYVFIYGYESKDSIRDIINSVKK
                     QMNNTLLKLHDGTEFKIRASAGISWYPDDSTNYDELMRYADFAMYQIKNTIKGEVSEF
                     DINIYNKDSFLLSNREELNKLIDGQLVEYAFQPIVDCKGKVFAYEALMRPKIKTFSSP
                     IDVIRLARSQSKLYQIERITWFKALKSFKKYKEKFGDCKLFLNSIPNNNLSKVDFEEI
                     EDLYGEYLNRVVLEITENDKINEDFIEKKKAYIDHWNIEIALDDFGTGYNGDAVLLYI
                     MPDYVKIDMSIVRGIDKDENRQKILKNLISYSNERNIKVIAEGVETKGEMETLINLGV
                     DYMQGYYISKPSFIPEDISDKIKKELKICHENRNDVV"
     gene            complement(8721..10181)
                     /locus_tag="KRH23_001527"
     CDS             complement(8721..10181)
                     /locus_tag="KRH23_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HHS5224810.1"
                     /translation="MNRCKFAKLIITSMIVLLLTGCSLKKEDNYKLDPENPTSIQIWH
                     YYNGQQKMAFDKLVKEFNDTVGAEKGIIVEAFSQGNVVDLSEKVLDSANKKVGSEDVP
                     NIFAAYSDTAYEMDKLGLLVDMDKYISKEELNEYIDEYVEEGRINSKDEFKLFPIAKS
                     TEILMLNKTDWDKFAKATNSNINDIKTIEGLVETSKKYYEWTDSLTKEPNDGKAFFGR
                     DALANYIIIGSKQLGVEIFSVKDGKVTLNIDEKVMKKLWDNFYVPYINGYFASYGKFR
                     SDDAKTGDILALVGSSSGAAYFPDRVMLNDNESYNIETSVFQAPRFKGEGKYAVQQGA
                     GMAVTKSTKEEEYASVEFLKWFTDKEPNIKFSIASGYLPVKKKTNDLDVIKEVMKKDN
                     LSLSDKVEGSIASSIEQINSCNLYTNKAFDGGTKARQILEYSMLDKAKEDSNKINELV
                     KSGTSKKDAVAQFNNDKNFKTWFESFKAELENAIKK"
     gene            complement(10273..10647)
                     /locus_tag="KRH23_001528"
     CDS             complement(10273..10647)
                     /locus_tag="KRH23_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224811.1"
                     /translation="MGNKNKNTKYKDKTRERYNKKVENLNKEKLNKVNKQSKKVDKID
                     DIINKSSIVLCVLLVVFSLLYLFKLVQLNIIMILLVITVAIQQGLVSFGAFRNKNYVK
                     ALFSIFVIVCFLIAFKYVVNPV"
     gene            complement(10823..11563)
                     /locus_tag="KRH23_001529"
     CDS             complement(10823..11563)
                     /locus_tag="KRH23_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor protein MotB"
                     /protein_id="HHS5224812.1"
                     /translation="MLYDEDEKEENNERWLLTYSDLITLLMIFFVIMYSMSNVDAEKY
                     KQLSQSLNSAFGGSSGVIEGGNSKIEPVVEAGSNDLDTLQNAKFKKIGEEIQKYLNEN
                     GMANSVSLRVQDRGLVISLKDTILFDTGKAIVKDNSRDKIIQIGKMLNEMNSYMRVEG
                     HTDNMSIKNSEFKSNWDLSVMRATNVVQLLIDNAGIAPDKLSAVGYGEFRPIAENSSE
                     EGRSKNRRVDIVLVDSKYDNVENVSKDK"
     gene            complement(11584..12372)
                     /locus_tag="KRH23_001530"
     CDS             complement(11584..12372)
                     /locus_tag="KRH23_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor protein"
                     /protein_id="HHS5224813.1"
                     /translation="MTTLIFFIVGIASLVVAFVIDGGHVGALFVFSSALVVFGGTIGA
                     VGASTPFPVFKKSIKIMLLAFKNKKPNNIENIIYFKEIATKARKEGLLSIDKEISEND
                     ELDPFIRKGLELMVDGVDAVTIRNILESQIQITSKRHKEGIAIFDSAGGYAPTLGIIG
                     TVMGLVHILGNLSSNPDALGPQISVAFLATLYGVGSANLIWLPIASKLKAINQQEVSE
                     RLLVIEAILSILEGDNSNLMTEKLKIFLNSKELIELEEIGGRAE"
     gene            complement(12460..12550)
                     /locus_tag="KRH23_001531"
     tRNA            complement(12460..12550)
                     /locus_tag="KRH23_001531"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(12514..12516),aa:Ser,seq:gct)
     gene            12809..13573
                     /locus_tag="KRH23_001532"
     CDS             12809..13573
                     /locus_tag="KRH23_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HHS5224814.1"
                     /translation="MLPQERYEKILSILKSDNIIKINDIVQMFDISIETARRDLAHME
                     SIGLLKRVYGGAIPVIASSVELNYVKRKKINSNDKKQIAIKCSEFINTNDTIFMDTGT
                     TVLEVSKNLKDKKNLTVITNSILVANELMNTNIKVYVLGGYLRETEGSFSGPLTLSAI
                     EQFNVDKAILGAGGITLENGISDYHLEEALVRKKMIERSRKSIVVVEPPKFGINSFAS
                     VAPIEHIDTIITSASIDHNIIIEFSQKGIPLVIADN"
     gene            complement(13854..14969)
                     /locus_tag="KRH23_001533"
     CDS             complement(13854..14969)
                     /locus_tag="KRH23_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization protein EutH"
                     /protein_id="HHS5224815.1"
                     /translation="MPFDKIILYIMAVGVLLGALDRIIGNKFGLGEQFEEGFNSMGPL
                     ALGMVGIVCLAPVISDVLGPIIIPIFNLCGADPSMFATILANDMGGYPLAMELAHNKE
                     AGMLAGLVVSSMLGCTLVFSIPVGLGLIEYEDRPFFAKGLLIGLITIPFGGIIGGLIA
                     GFNLSMVIINMIPVIILAVILAVGLKFNSTLMINGSLVFGKFISILITIGLGAAAFQE
                     ITGIVLIKGMTPIREGIQVIGSIAIVLLGTFPILHLLVKVLNKPLTIVGGKLGMDATS
                     AAGLVFTLANSIPVYKMMKDMSPKGKVVNTAWLVCATAALGDHLGFTAGVVPEMITPV
                     VIGKLVGGVLAIALAILMTKDLTLEEEQSIKMKKDAV"
     gene            complement(15010..16536)
                     /gene="glpK"
                     /locus_tag="KRH23_001534"
     CDS             complement(15010..16536)
                     /gene="glpK"
                     /locus_tag="KRH23_001534"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004370 - glycerol kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006072 - glycerol-3-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HHS5224816.1"
                     /translation="MKYVLAIDQGTTGTRAVLINEKSEFVFSDYMEHTQIYPQSGYVE
                     HDPIEIWNNTKTVSNNVLQQAFENGINESDIKGIGIDNQGETVMLWDKNTGKPLYNAI
                     VWQCRRTYDYVENLKNIPGLENKIIDKTGLIIDPYFSGTKIKWVIDNVKGVKEKIKNG
                     EVLAGTLDSWLIWKMTGGKSFLTDVSTAARTMLFNIRDMDWDRELLDIIGVPRSILAD
                     IMPTSGDFGTTDKEAFCGVSIKITASMVDQPAALFGNGCFEPGMVKNTYGTGCFLYMN
                     IGEELNIAGNGILTTVAWKIGDKVTYAYDGGVYIAGAAIQWLRDGIGVIKNYSETDDM
                     ANSISSTGGVYFVPAFAGIAAPYWDQYARGTMVGITGSTKKEHIVRATLESVALQVKD
                     VVDSMNLASGKKIKMLRVDGGITKNNFTMQFQSDILGIPIEIAENPETTVLGVGYMAG
                     LSCGVWNSIDEIRSEFTISKKYIPNMTTQKREEILLGWNQAVKRAMNWENDTKKVCAN
                     "
     gene            16829..17926
                     /locus_tag="KRH23_001535"
     CDS             16829..17926
                     /locus_tag="KRH23_001535"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal-phosphate-dependent aminotransferase
                     family protein"
                     /protein_id="HHS5224817.1"
                     /translation="MKKTYLFSPGPVMVTDKVRNSLLHYDICHRGNEFMDLFKDTQQK
                     INKLYNATSNYYSLIVSGSGTSVNECVLSSIFDKEDAVLLVSNGVFGERLEEILSTYN
                     VKTYKPNFEWAEYPDLDILEKYIIENSDIKVIAMVFHETSSGMINPVPELGKLAKKYN
                     KIFFVDAISASAGEYIDVEEFNIDIITGVGGKALGAFPGSAYLCAKESILQNIKENQC
                     KNVYLNLYKHYKVAKSSSQTPNTPNVTLIFALNEALTEFLEDDSKIERYKECSAILRN
                     GMEELGLTFLLPDKYMSNTVTSVFLPKEINVNEFILGLERESGYVVYPGKGKFLDANI
                     FQVANMGEIYPEDCYKFLDILKSKLEIKKVI"
     gene            complement(18751..19263)
                     /locus_tag="KRH23_001536"
     CDS             complement(18751..19263)
                     /locus_tag="KRH23_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224818.1"
                     /translation="MKVKKFKSGIVMALTVMAIGASLTNVSAMELNKSKEFETKYNEM
                     KRDFQEEYGKEDKFNITLNDEFTKEEVNGAKGIIKTTNKMNNEVVVLNYFDEMKSGIE
                     FELKPKAEKNAILRDEFQQGYGKEDKFKVVLDDEFTKEEVNGAKGIIKTTDKETGEVI
                     VYNYFDELEK"
     gene            19816..20697
                     /locus_tag="KRH23_001537"
     CDS             19816..20697
                     /locus_tag="KRH23_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HHS5224819.1"
                     /translation="MKKRLIIMILSVVLVLSSILTIFAYSNIKYNNNKLIYSNMIDKK
                     TQNSVKEILKENKINEKDIDTFIKAVNNYNKLQVKILQNNINISKSGYSSINAKQVPY
                     NLEKLQDNWVKKFPDYMDVNCRITAFRLFKDFINSNKKFTGDSIDLNVDLDTIMNNKD
                     AKFSTKDVEKFINFFSAIPAKDTDDTIKIAEQIKNEWKKRKISFKNNKNISIINGFLR
                     YPETKNVFIGHTGICIKTKNGILFLEKYGVTSPYQVTKFKNKEDVKNYMFNRLKMSEG
                     EIELPDPIIMENDKLMK"
     gene            complement(21010..21789)
                     /gene="hisJ"
                     /locus_tag="KRH23_001538"
     CDS             complement(21010..21789)
                     /gene="hisJ"
                     /locus_tag="KRH23_001538"
                     /EC_number="3.1.3.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004401 - histidinol-phosphatase activity
                     [Evidence IEA];
                     GO_process: GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphatase HisJ"
                     /protein_id="HHS5224820.1"
                     /translation="MKDGHIHSPYCPHGSKDDFEKYVQRAMDVGITEMTFTEHFPYAN
                     GFRDPAPENDSCMSIEDLPKYFNDVKKLKEKYEGKIKINVGSEVDFIEGYEEGIKANL
                     NKYGEELEDSLLSVHIIKIDDDYYCVDYSVEEFQNLIDKLGSIEAVYNKYYETLIKAV
                     NSDLGIHKPKRIGHLNLVRKFNQVFPYDYKGNKILEELIKLIKEKGYELDYNVSGNRK
                     EYCKEPYIDGYLLDLVKKYDIPLVLGSDSHCAEEINKYDII"
     gene            complement(22335..22685)
                     /locus_tag="KRH23_001539"
     CDS             complement(22335..22685)
                     /locus_tag="KRH23_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc transporter"
                     /protein_id="HHS5224821.1"
                     /translation="MIFDKEIVRYHHGHHDHDHCHEHTHGDICHEHPHDHAHDHDHEH
                     SHEESSESKDEKTLKILLVHWINHNETHEEGFREWVEKARAIGKEETAKSIEKAIEYM
                     EEANKMLLEAKKHM"
     gene            complement(22701..23117)
                     /locus_tag="KRH23_001540"
     CDS             complement(22701..23117)
                     /locus_tag="KRH23_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3842 family protein"
                     /protein_id="HHS5224822.1"
                     /translation="MIIAVIDGMGGGIGAQIVSSLREELPTYVEIYALGTNSIATSSM
                     MKAHANKGATGENAIVVSAKKANIIVAPISVIIPNSMMGEVTCNISEAIADSEALKIL
                     LPIMPENVELVGLEGKPLALLVKDSVNLIKKEFNIK"
     gene            complement(23136..23327)
                     /locus_tag="KRH23_001541"
     CDS             complement(23136..23327)
                     /locus_tag="KRH23_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CooT family nickel-binding protein"
                     /protein_id="HHS5224823.1"
                     /translation="MCESSAFICKSNNELEKVMENVVNIDPCDGKIYLTDLLGEQKII
                     DGIIKEIRLMDHKIIIQEN"
     gene            complement(23478..24293)
                     /locus_tag="KRH23_001542"
     CDS             complement(23478..24293)
                     /locus_tag="KRH23_001542"
                     /EC_number="2.3.1.-"
                     /EC_number="6.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009107 - lipoate biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009249 - protein lipoylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HHS5224824.1"
                     /translation="MNQWRVIHNKSYEGAMNMAIDEAIFTAYKKGHNKPTLRFYTWEP
                     ACLSIGYFQKLEDEIDLDKCRCMNIDYTRRITGGRAVLHDNELTYSIIIGEDNPLIDK
                     SINLSYRYISEGLVKGLNLSGIETDNLNRGERISRENLSAACFNAHASYEVTINNKKV
                     IGSAQSRKDGVLLQHGSIILDFDVEKLFKLIKTKTPELKERAMKFTAKKASGIENEIG
                     RKIDIDILQKNIVKGLAEQFNVEFVEGDLTDYEKQLVKELYEKYKNEEYNKKR"
     gene            complement(24340..25278)
                     /locus_tag="KRH23_001543"
     CDS             complement(24340..25278)
                     /locus_tag="KRH23_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HHS5224825.1"
                     /translation="MIRLSVGTAIELGILNKKSDIPPTTAYIMIGEKCINKCSFCSQS
                     IESSTRKDKLSRVIWPEFSKEEILDALKAYKGKNIKRICIQSMASEEAHNSVLDFINY
                     ISGKIDMPISLSAKLENDEQIKKFFSAGVDKIGIAIDAANKELYEKIKGNNYDEKLKF
                     ITEMSKSYPNKISTHIIVGMGESHEDIYNLYTYLKENDVTISLFAFTPVRGTKMEKIN
                     QPSIESYRRVQLMSYMINKGYPKEYFKFKNGYLNSIKLDNDILKDINKGYPFEIRGCK
                     DCNRPYYNERPGSTIYNYSRPLNQSEIDLAIREINL"
     gene            complement(25275..26147)
                     /locus_tag="KRH23_001544"
     CDS             complement(25275..26147)
                     /locus_tag="KRH23_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HHS5224826.1"
                     /translation="MNKNLSEKMKIAFDIKLKNFGNKIEFAYPNQTLALSTTSNQCSL
                     KCAHCNGHYLNNMVPIEEYEEKVQSRNITSFLLSGGCSYEGDVPINTHINTIKNLKEQ
                     GYRLNAHLGLMDKDSIVELCKYLDIVSFDLVFDDETIREVYKMKKSKEDYIEVYNTIQ
                     EHTEVAPHICIGLKGGQIKGEYEIIEYLQKNPPNKLTFIVLIPTKGTEYENVEPPELE
                     GVADILCEARINLPDTEINLGCMRPRGVYRKELDQLSIMCGVNRIVLPSRSAKNKAIE
                     MNMTINECKECCVL"
     gene            complement(26172..28100)
                     /gene="acsV"
                     /locus_tag="KRH23_001545"
     CDS             complement(26172..28100)
                     /gene="acsV"
                     /locus_tag="KRH23_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="corrinoid activation/regeneration protein AcsV"
                     /protein_id="HHS5224827.1"
                     /translation="MIKVSFTPNNKEVYCNEGDILLEVARNADIFIDAPCNGNVSCGK
                     CKVKLLNGKVDTEKTRHITDDEWEQGYILACCTKVISDIEIEVPSKVSSSMHGMKIEG
                     SNKKEDREIFERAKKIIEEHNLQFKTNIKKKYIEMEEPNLDDNISDVDRLERYVRNNL
                     GYNEIDFRLDILRKMPTVFRKSDFKVTITYVQKQKKLTIINIEQGNKENSLYGVAIDI
                     GTTSVVVCLVDLYSKEVVDKASSGNAQIKYGADVINRIIYSTKKNGLETLHKAIVEET
                     INPLLKTIYERNGIDKEDVVTLVAAGNTTMTSLFLGVYTDFLRQEPYIPPFLKSPKLM
                     GENVGLFVNDSAYVYLAPSVASYVGGDITAGVLSAGIWSSEENVLFIDLGTNGEIVFG
                     NKDYMMSCACSAGPAFEGGGISCGMRASAGAIEKVIIDKDTLEPTLKIIDECAPVGIC
                     GSGIIDLICQMITKGVIDRRGKIYRDLDNKRVRFNEHEIGEYVLAFKEEFDLENDIVV
                     NEVDIDNFIRAKGAIYSGAYTLVDSLGMDFSILDRVYIAGGIGNNLDIENSIIIGLLP
                     DIDREKFTYIGNSSLVGSYLALISKDAKNKLEEIGNQITYVELSVYPSYMDEFISACF
                     LPHTNIEQFPTAKKLLEE"
     gene            complement(28212..28589)
                     /gene="gcvH"
                     /locus_tag="KRH23_001546"
     CDS             complement(28212..28589)
                     /gene="gcvH"
                     /locus_tag="KRH23_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005960 - glycine cleavage complex
                     [Evidence IEA];
                     GO_process: GO:0019464 - glycine decarboxylation via
                     glycine cleavage system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein GcvH"
                     /protein_id="HHS5224828.1"
                     /translation="MKLLPELKYSKDHEWVKVIDGDVVYIGITDYAQDQLGEILFVET
                     PEVEDTVTKGVDFGVVESSKVASDLISPVNGEVLEVNEKLEDEPECINEDPYENWILK
                     VKLADVAELDTLLSDKEYEAGLE"
     gene            complement(28676..30802)
                     /gene="acsB"
                     /locus_tag="KRH23_001547"
     CDS             complement(28676..30802)
                     /gene="acsB"
                     /locus_tag="KRH23_001547"
                     /EC_number="2.3.1.169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA decarbonylase/synthase complex
                     subunit alpha/beta"
                     /protein_id="HHS5224829.1"
                     /translation="MNLYNIIFTGSEQALGAAQAMLAEAIEKNGKEHKVAFPDTAYSL
                     PCIYAATGQKMNTLGDLEGALEVVKSLINRTHLLEHAFNAGLATALAAEVIEALKYST
                     MDAPYSEPCAGHITDPIIRSLGVPLVTGDIPGVAVVLGECPDAESAAKVIKDYQSKGL
                     LTFLVGKVIDQAIEAGVKMGLELRVIPLGYDVTSVIHVVSVAVRAALIFGGLTPGDLN
                     GLLEYTANRVPAFVNAFGPLSELVVSAGAGAIALGFPVITDQTVLEVPMNLLTQKDYD
                     KIVATSLEARGIKIKVTEIPIPVSFAAAFEGERIRKSDMFAEFGGNRTEAWELVVKKE
                     ATEVEDHKIEIIGPNIDEVDADGVLRLPLAVIVKIAGKNMQEDFEPVLERRFHYFLNY
                     IEGVMHVGQRDMAWVRISKDAFDKGFRLEHIGEVLYAKMLDEFESVVDKCEITIITDA
                     EKVSELKGEAIAKYNARDERLASLVDESVDTFYSCNLCQSFAPAHVCVVTPERLGLCG
                     AVSWLDAKATKELDPTGPCQPIEKGECLDDRTGVWNSVNETVNQISQGAVESVTLYSI
                     LEDPMTSCGCFECICGIMPEANGFVVVNREFASVTPVGMTFGELASMTGGGVQTPGFM
                     GHGRHFISSKKFAYAEGGPERIVWMPKELKDYVADKLNATVKEMTGIENFCDMVCDET
                     IADDSEGVLAFLEEKGHPALAMESVM"
     gene            complement(30859..31665)
                     /gene="acsE"
                     /locus_tag="KRH23_001548"
     CDS             complement(30859..31665)
                     /gene="acsE"
                     /locus_tag="KRH23_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon monoxide dehydrogenase/acetyl-CoA
                     synthase methytransferase subunit"
                     /protein_id="HHS5224830.1"
                     /translation="MEKFMIIGERIHCISPSIRKALAERDPAPILKRAKEQLEAGAHY
                     IDFNIGPAERDGEEIMTWGIKLLQSEFNNVPIALDTANKKAIEAGLKVYDRTNAKPII
                     NSADAGSRFDLIDIAAEYEAMVIGLCAKEGIPRDNDERMAYCQEILEKGLMLGMEPTD
                     ILFDPLCLVIKGMQEKQVEVLEAIKMMTEMGLLTTGGLSNVSNGCPKHVRPVLDSAFL
                     AMAMANGFSSAIMNPCDPELMKTVKSCDIINGASLYADSFLELNEGGFAF"
     gene            complement(31715..33082)
                     /gene="acsC"
                     /locus_tag="KRH23_001549"
     CDS             complement(31715..33082)
                     /gene="acsC"
                     /locus_tag="KRH23_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA decarbonylase/synthase complex
                     subunit gamma"
                     /protein_id="HHS5224831.1"
                     /translation="MALKALDIFKLTPKKNCKDCGFPTCMAFSMKVASGAVEVGKCPH
                     MSDDAIAKLSEATAPLMKALKVGAGASEYELGGETVLFRHEKTLVSRNRYAVSFCTCM
                     SDEAVDAKIANMKKVDYVRIGEQMKVEMAVLEYCGDKDAYLKLIDKIKGSGLEVAYIL
                     ACDDAQVVKEAVEVLKDARPMVYGATKENYKDMIEVVKGASLPLGVKAGSLEELYETV
                     ELIQAAGYKELVLDVTGENIKDTYTNAIQVRRTALKEQDRTFGYPSIVFANRLSNSNP
                     MMEVALSSIFTIKYGSIIVIDDISYAKALPLFALRQNIYTDPQRPMRVEPKIYPINNP
                     DENSPVLVTVDFALTYFIVAGDIERSKVPVWLVIPDAGGYSVLTSWAAGKFGGNSISA
                     FIKESKVEEVTNCKDLIIPGKVAVLKGDIEDNLPGWNVVIGPEESMELPKFLKGYQEK
                     ACQTN"
     gene            complement(33113..34057)
                     /gene="acsD"
                     /locus_tag="KRH23_001550"
     CDS             complement(33113..34057)
                     /gene="acsD"
                     /locus_tag="KRH23_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA decarbonylase/synthase complex
                     subunit delta"
                     /protein_id="HHS5224832.1"
                     /translation="MAFKMSTQKYSGKISEVEVGIGEKAIKLGGENVLPFYSFDGEVG
                     NSPKIGIQISDVYPESWTDSYKELYKDVANCPVEWAKYVEANTQADFICLKFDGSDPN
                     GLDKSVDECADVAKAVIEAIKLPLVVAGSGNHEKDGKLFEKLAQTLDGHNCLFMSAVE
                     DNYKGVGASAGMAYAHKVGAESSVDINLAKQLNVLLTQLGVKGENIVMNVGCSAVGYG
                     YEYVASTMDRIRLAAFGQNDKTLQMPIITPVAFEVGHVKEAIAPIEDEPDWGCPEERT
                     IAMEVSTAASVLVGGSNAVILRHPKSIETIKELVNALA"
     gene            complement(34077..34847)
                     /locus_tag="KRH23_001551"
     CDS             complement(34077..34847)
                     /locus_tag="KRH23_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon monoxide dehydrogenase accessory protein
                     CooC"
                     /protein_id="HHS5224833.1"
                     /translation="MGYNIAVAGKGGTGKTSLTGLLIDYLVKDKKGPVLVVDADANAN
                     INEVLGIEVEATIGEIREEVNQREKLGNAFPGGMTKAQYLQFRLNSIIEEGEGYDLLV
                     MGRSEGEGCYCFVNGILREQVNKISGHYKYLVMDNEAGMEHLSRKVTRHVDTLLLVSD
                     CSRRSIQAVARIRDLAEELKLSVGRILLIVNKVPNGVMNDGVKEEIEKHNLELIGVVP
                     MDELIYEYDSTGIPLVNLPEDSKSKVAMKEIFAKLELK"
     gene            complement(34903..36288)
                     /gene="lpdA"
                     /locus_tag="KRH23_001552"
     CDS             complement(34903..36288)
                     /gene="lpdA"
                     /locus_tag="KRH23_001552"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004148 - dihydrolipoyl dehydrogenase
                     (NADH) activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HHS5224834.1"
                     /translation="MKIVVVGGGPGGYVAAIKASMLGADVTVVEKRRVGGTCLNAGCI
                     PTKALLASSGVLNTVKEAKDFGIEIDGTVKPNFTAIMERKNKVVNQLISGIEFLFEKR
                     GVNLVNGFGKLIDKNTIEVTKDDGTVETIKADKIILANGSVPVVPRMFPYDGKVVITS
                     DEVLGLEEIPESMLIVGGGVIGCEIGQFFRALGTEVTIVEMVDQILLNEDKDVAKQLL
                     RQFKKDKIKVITGIGVQTCEVVDGKAVATLSNGKVIEAQYALVCVGRRPNLDNSGVED
                     IGIEMERGKVVVNEHLETNVEGIYAIGDIIDTPFLAHVASKEGIVAVENALGKTKVVD
                     YRAIPRCVYTEPEVAGVGKTEKQLEAEGVEYNVGQFDFRGLGKAQAIGHFQGFVKVIA
                     DKETDKIIGAAVVGPHATDLLTELSLAVHLGLTVEQVGDAIHPHPSLSEGLMEALHDV
                     HGECVHSVPKL"
     gene            complement(36332..37213)
                     /locus_tag="KRH23_001553"
     CDS             complement(36332..37213)
                     /locus_tag="KRH23_001553"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004489 - methylenetetrahydrofolate
                     reductase (NAD(P)H) activity [Evidence IEA];
                     GO_process: GO:0006555 - methionine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase"
                     /protein_id="HHS5224835.1"
                     /translation="MSLLRETLESGKFAVTTEMAPPKGTDLSHLIECAKPLVGRVHAA
                     NVTDFQSAVMRATSLATCKLLKDAGLEPVIQITGRDRNRIAIQGEMLSAGVFGINNLL
                     ALTGDHTSVGDHPQAKGVFDLDSVGILQTAETLMAGTDMAGNKLKGSPDFYLGASVTP
                     EYSPIEVQLLKMKKKIKAGAKFFQTQALYDINTMRKFRELTRDMDCKVLAGIVPLKSP
                     GMAKFMTANVPGIFVPDEQIERLRAAGKENWVSEGIKMAGELIKQLKEEDLCDGVHIM
                     AIGAEENIPAILDAAGL"
     gene            complement(37249..37923)
                     /locus_tag="KRH23_001554"
     CDS             complement(37249..37923)
                     /locus_tag="KRH23_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase C-terminal
                     domain-containing protein"
                     /protein_id="HHS5224836.1"
                     /translation="MIISENKPLEEVLGYLKDFDKLVLVGCNQCAATCKSGGEEEVLK
                     MKETLEGEGKKILGYVMLDPACNLLKSKKDLKALKEETKEADAVLSLACGDGTQTIVK
                     NLKDKPVYPANNTLFIGEVQRVGEYEEACKACGDCELGWTGGICPVTMCAKGLMNGAC
                     GGAKNGKCEVNSENDCAWIKIYERLEAIGQLDNLAEIRPPKDYSKQNNPRSLSAKKKK
                     EAAANS"
     gene            complement(37960..38832)
                     /locus_tag="KRH23_001555"
     CDS             complement(37960..38832)
                     /locus_tag="KRH23_001555"
                     /EC_number="1.5.1.5"
                     /EC_number="3.5.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0004488 - methylenetetrahydrofolate
                     dehydrogenase (NADP+) activity [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 5,10-methylenetetrahydrofolate
                     dehydrogenase/5,10-methenyltetrahydrofolate
                     cyclohydrolase"
                     /protein_id="HHS5224837.1"
                     /translation="MEGMSTKGQIIKGKPVADKISEELIKEVDLLIKEGINPKLTIVR
                     VGARSDDLSYERGALKRCQNIGITTEVLELAEDITQEEYIDVLKRVNDDKNVNGILCF
                     RPLPKHLNEEVIKYVIAPEKDVDCFSPINSAKVMEGDKSGFPPCTPTAVVEILKHYNV
                     DLKGSKVTVLGRSMVVGKPVSMLLLSEHATVTICHSKTKNLSGVAAEADVLIAAIGRA
                     KMVDESFVKDGAVVIDVGINVDEEGNLCGDVDTNAVLDKVSMITPVPAGVGSVTTSIL
                     AKHVVKACKLQNNK"
     gene            complement(38924..39556)
                     /locus_tag="KRH23_001556"
     CDS             complement(38924..39556)
                     /locus_tag="KRH23_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cyclodeaminase/cyclohydrolase family protein"
                     /protein_id="HHS5224838.1"
                     /translation="MKIADKTCVDFVEVLSSKEAVPGGGGAAALVGAIGMALGSMVCN
                     LTIGKKKYAEYEESVKEILSKAGKLEKDLLKMIDDDAECFLPLSKAYGLPKETEEEKR
                     IKAETMEKALKVACEVPLNIVRVCYEAIKLHEDLVDKGSRLAISDVGVGVQCLRAAIL
                     GGQLNVVININSIQDKEYVNKVKTEVDKLVEDGVKICDEVYAKVEKALGK"
     gene            complement(39661..41337)
                     /locus_tag="KRH23_001557"
     CDS             complement(39661..41337)
                     /locus_tag="KRH23_001557"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014355320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004329 - formate-tetrahydrofolate ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HHS5224839.1"
                     /translation="MGFKSDIEIAQEAKPQDIREVAKKLGLGEDDVELYGKYKAKVDY
                     NLLKRETGKKAKLILTTAINPTPAGEGKTTTTIGVADAFAKLDKNVLVALREPSLGPV
                     FGVKGGAAGGGYAQVVPMEDINLHFTGDFHAIGAANNLLAAMLDNHIHQGNALRIDPK
                     KITWRRCVDMNDRQLRNIVDGMGKKGDGAVRQDGFDITVASEIMAAFCLASDISDLKE
                     RLGNIIVGYSYEGEPVTARQLKANGAMAALLKDALKPNLVQTLEGTPSFVHGGPFANI
                     AHGCNSVIATRMAMHFADYVITEAGFGADLGAEKFLDIKCRMANLKPDAVIIVATVRA
                     LKYNGGVAKADLNNENLEALEKGLPNLLKHVENITQVYGLPAVVAINRFPLDTEAELK
                     LVEDKCKELGVNVALSEVWAKGGEGGIAVAKEVLRLLDEEENNFRFCYEDDLSIKDKI
                     NAIATKIYGADGVDYTPEADKEIANLEKLGFTKVPVCMAKTQYSLTDDQTKLGRPTGF
                     RITVRQATISAGAGFIVALTGEIMKMPGLPKVPAAEKIDVDENGVIAGLF"
     gene            complement(41586..42365)
                     /locus_tag="KRH23_001558"
     CDS             complement(41586..42365)
                     /locus_tag="KRH23_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HHS5224840.1"
                     /translation="MKIAITGKGGVGKTTFSSMLSRMFAEDGYRVVAVDADPDANLAL
                     ALGFPKEVYESIVPISEMKKLVSDRTAASVGSFGKMFKMNPKVDDIPENFCKEYNGVR
                     LLTLGTVDSGGTGCVCPEHVLLKRLCSHLILQNKDVVVMDMEAGIEHLGRGTAQGVDA
                     FIVVVEPGERSLQTYRKVKKLGHDIGVNKVFVVGNKIRNKEDEEFIIQNLEDGESLGF
                     IYYNQDVIDSDRANQSPYDSSETTKEQIKAIKDKLMSLKNK"
     gene            complement(42685..44604)
                     /gene="cooS"
                     /locus_tag="KRH23_001559"
     CDS             complement(42685..44604)
                     /gene="cooS"
                     /locus_tag="KRH23_001559"
                     /EC_number="1.2.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016151 - nickel cation binding [Evidence
                     IEA];
                     GO_function: GO:0043885 - anaerobic carbon-monoxide
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0006091 - generation of precursor
                     metabolites and energy [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic carbon-monoxide dehydrogenase
                     catalytic subunit"
                     /protein_id="HHS5224841.1"
                     /translation="MDEKMLTIDLNSQKMIAKAREEGVETMYDRKEGFKAQCGFGLQG
                     VCCRICGMGPCRISPKTPRGLCGADEHTIVGRNFARMVAGGTAAHSDHARDIAHTLAL
                     ADPNGNYKIRDEAKLITLAKEWDVETEGRDIYDVAHEVAEIALMEFGKPFGTLRFIKN
                     APEPRQKIWKEYAIEPRAIDREIATIMHSTHIGCTGDIDSLIHMSLRTSMADGWGGSM
                     IGTRLSDILFGTPVPRRTEANLAVLEENKVNIILHGHEPALSEMIVLASEEPDLVALA
                     KEVGADGINLAGMCCTGNEITMRHGVKIAGDFHQQELAIITGAVEAVIVDVQCIFPAL
                     ARVADCYHTKFVTTSPKAKITGSTYIEFREEQALDDAKAIVKEAILNFKNRDKSKVLI
                     PELKSGATVGYSVEAVVNQLDRVVNSHIDPAGTVKPLTDCLKSGVLRGAAGVVGCNNA
                     KGVSNEAHVTIMKELIKNDIIVVTTGCGASAAAKFGLMESDAAEKYAGKGLATVCKLV
                     GIPPVLHMGSCVDISRILDLVGAAANYLDMDMCDLPVVGIAPEWMSEKAVAIGCYVVA
                     SGIDTYLGIMPPIAGSSRAVDILTSELKDKVGATFTVNTNPKELAATIIEDIEKKRVH
                     FEALVEEKMAEKAEA"
     gene            complement(45211..46122)
                     /locus_tag="KRH23_001560"
     CDS             complement(45211..46122)
                     /locus_tag="KRH23_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional enoyl-CoA hydratase/phosphate
                     acetyltransferase"
                     /protein_id="HHS5224842.1"
                     /translation="MIKKLDDILEQLKGGEKIVLSVAAAHDKEVLMAIKDAVERNIIT
                     PILVGNEGKIREISKEIGFDLSGIKIVDKDDIKECAEIAVKLVSSKEADFVMKGLLDT
                     SVILKEVLNKDYGLRTDSLLSHVMVYELEKYHKLLITTDGGMNIAPDYEQKAKILKNS
                     IKAAKALGMETVKVACLAAKEKVNPKMQATVDADMLAKACKEGEFGENVIVEGPLAFD
                     LAVSKEASEIKGFKSEVSGDVDIILVPTIEVGNGIGKAFTYMADSKSAGIIMGAKAPI
                     VLVSRADSHESKLYSIAYGAIVAKNMK"
     gene            complement(46238..46372)
                     /locus_tag="KRH23_001561"
                     /pseudo
     CDS             complement(46238..46372)
                     /locus_tag="KRH23_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902116.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
     gene            complement(46455..47597)
                     /locus_tag="KRH23_001562"
     CDS             complement(46455..47597)
                     /locus_tag="KRH23_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HHS5224843.1"
                     /translation="MDFKIEKYLLKKAEELAFITIKHGGEFKLKSYEVPKGGLDVPIK
                     NEVLVKGIKEKTAQDKLNSMSIADAMIYIIGIDSKFKNNAEYEKFLNALSKDIDLDLK
                     SYMGYMSRKYFEIGEHTDSLIYIKAFITMYPDDLDAMYNYAIVCQEIAKQYQKDMDDK
                     AMNAFLLEAMAKLEKVIDVDENFALGYYHLGYHYYNQGQYLKTKLTWEEALRLGLDAD
                     LVAEVQENLGKMDFKVQYEEGYTLVFQGKFKEGLEKLLPLEEEHMDWWNLLFMIALGY
                     KGMGEIEQAKMYLKKILIIKPNQVDTIVELGLCEAYKNNLDKAIEYFEQAAKIKEDPE
                     ILCNLGMAYLNNGDIDDATYYIERAYELNPQDEITIACLRELGINK"
     gene            complement(47615..49369)
                     /locus_tag="KRH23_001563"
     CDS             complement(47615..49369)
                     /locus_tag="KRH23_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="B12-binding domain-containing radical SAM
                     protein"
                     /protein_id="HHS5224844.1"
                     /translation="MKILLTTLNSKFIHTNLAIRYLKEFVRDLIEVNMKEYTINNDLD
                     YILKDIYKNEYDIILFSTYIWNVGDIVKLCDNLKKIRPNTKIALGGPEVSYDSYEAMK
                     KYDFVDYILYGEGELIFRDLVLHLQGKMEINDVNGLVYRQGNEIIVNKPMELLQDLDE
                     IPSPYENLNPKEYENRIVYYESSRGCPFNCQYCLSSTIPGLRYFSLDRIKSDLKALID
                     ARVSQIKFIDRTFNANRKVAMEIMDFLMKNDNGYTTYHFEVTAYLIDDKMLEFLADCK
                     EGLFQFEIGVQSTNEKTLDAVGRRDDFKKLSHVVQTVASYRNIHQHLDLIAGLPYEDY
                     KSFENSFNDVFNLGIEHLQLGFLKMIKGTGMRKVADEHGFKYKDYAPYEFLYNNYISY
                     EETLKLKDIENILERYYNSKNFVLSMRYIIGRFYKQSPFKFFEVFAKYFDENGYFDLA
                     QGKNQLYKILMDFYNEKINIDNDVFNDILKYDYISLGKTSNIPQFFNKLDVDDFKNRC
                     HVFLQDNDNLSTYLPSFVDKPAKHIIKYVHFEPFRFNVVDLKNDINTEIREVENVVLF
                     EYDDKKIFEKSKTHKVEI"
     gene            49505..49711
                     /locus_tag="KRH23_001564"
     CDS             49505..49711
                     /locus_tag="KRH23_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224845.1"
                     /translation="MELIEKVSINSLSKRDLLLIIKSLEYTNENTQISDFIDLRNNIV
                     KELCFLTDTKEKDFLDYLEKNSTL"
     gene            complement(49716..50639)
                     /locus_tag="KRH23_001565"
     CDS             complement(49716..50639)
                     /locus_tag="KRH23_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224846.1"
                     /translation="MNDELLKKVYTSSFSSASRALKDLTIINTKSLIDDKTQRCVYID
                     ENRLRDELIYYRFYGEKIGNINFLNILLPLILSNTNIQKSEDEVIKLIKKYVIYFKKE
                     ELLFDYLLGSVVYNSIMHNLINNSKIEYVELLQSIKDKIIGFSIELDKSDVVKFQMAR
                     IKAIQLIDKYIDLKSEDYDEESILLNVLNVLYDVYMEDRTVENEGINSIKKSILSILG
                     EDSKLNEDNIDFIFSMSEYVVKLRKYKIGVKAYNKSIDPRSLIRLEEGNTIVDPIFNQ
                     ITVMSKTFNDNILSIKINSKSGIYILKFKKV"
     gene            complement(50893..52593)
                     /gene="argS"
                     /locus_tag="KRH23_001566"
     CDS             complement(50893..52593)
                     /gene="argS"
                     /locus_tag="KRH23_001566"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004814 - arginine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006420 - arginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HHS5224847.1"
                     /translation="MQDFKVAISNCLKEKIEDLSKEEIEALIEVPPNKDMGDYAFPCF
                     KLAKVFRKAPNMIASELAESIEPSGEITKVIQLGGYVNFFVNKSQLAETVIKKVLDEK
                     ENYGHSDFGKDKTVIVEYSSPNIAKPFHIGHIRTTVIGNALYKIYDSQGYKTIRINHL
                     GDYGTQFGKLIVAFKKWGEKEVVESNPIPELLKLYVRFHDEAEQHPEMEDEARAWFNK
                     LENGDEEAQELWQWFRNESLKEFNRVYKLLDIEFDSLAGESFYSDKMNRVIELLEEKN
                     LLKESKGARIVDLEEYKMPPALITKNDGSTLYMTRDLAAAIYRKETYDFDKCIYVVGS
                     QQNLHFQQWFKVIELMGYDWAKDLIHVGFGMVALEEGTMSTRKGRVVFLEDALNQAID
                     KTKEIILAKNPNAKNVDEISKQVGVGAVVFQELSNSRIKDYTFSWERTLSFDGETGPY
                     VQYTHARCCAVLRKAEVEVTSDIDYSLLADEDSAEVLRVIESFNKNILLALKKNEPHI
                     VTRFMLDLAQAFNKFYHDNPILVENLEIRKARLALVLATKQTLENSLKLLGMHAPERM
                     "
     gene            complement(52902..53315)
                     /locus_tag="KRH23_001567"
     CDS             complement(52902..53315)
                     /locus_tag="KRH23_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HHS5224848.1"
                     /translation="MILVSACLIGINCKYSGDNNDNEKVKEYLKGKEFTLVCPEQLGG
                     LSTPRPPAEIVDGKVITKDNKDVTENFVRGANETLKIANLYVCSEAILKEGSPSCGCN
                     LIYDGSFSGKKIPGKGITARLLEEEGIKVKSEKDL"
     gene            complement(53383..55761)
                     /locus_tag="KRH23_001568"
     CDS             complement(53383..55761)
                     /locus_tag="KRH23_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006259 - DNA metabolic process [Evidence
                     IEA];
                     GO_process: GO:0045910 - negative regulation of DNA
                     recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HHS5224849.1"
                     /translation="MNEKSLRVLEYNKIIDLLKKKASSSLGLKYIENLVPNTDFVEVK
                     SMLEETSEAQSIIIKRGSVGLEGIHDIEDKVKRAYIGASLDPGSLIMIADTLRVARRL
                     RNSLSSSDEEDFNYPIIQSLSNSLYVYKDIEDQIYNAIISEVEISDNASSTLRDIRRR
                     IAQKNQSIRSKLNSIISSTTYQKYLQDAIISLRGDRFVVPVKSEYRSQVAGIVHDQSS
                     SGATLFIEPMTIVEMNNELRQLKLGEQEEIERILSELSAMVGEVSEDLISNQEILGRL
                     DFAFSKGKLSIQMRGIEPTLNEDKYLNIKNGRHPLLDKKKVVANTIYLGRDFHTLVIT
                     GPNTGGKTVTIKTVGLFALMTQSGLHIPADYGSSMCVYDNVFADIGDEQSIEQSLSTF
                     SSHMTNIVSILQNVTADSLVIFDELGAGTDPVEGAALAIAVLEDINSVGAKCIATTHY
                     SELKNYALTKSGVENAAVEFDIETLSPTYKLLIGVPGKSNAFEISRKLGLSDYVISRA
                     KEYINTENIALEDVLQNVEKNRIKAVEDREEAERLKEEIEKLKVEYDEKLEKLVSQRD
                     KMIEKAKSEAFSIIRQAKEEVDIIIKELRSLEQERASKEKNRKIEELRKELTSSMGSL
                     QPTVKSMIVPKVSNKEIKDLKPGEEVKVITLNQNGSVVSVDKKRKEAVVQIGIMKMTL
                     PFKSLQKTRKDVSTNVTKSTRNIIRSKSGSVKNEVDLRGLNLEEAIMEVEKYLDDAYV
                     AGLESVTVIHGIGTGVLKAGLQDILRRNRHVKSQRGGQYGEGGAGVTIVKLK"
     gene            56080..57531
                     /locus_tag="KRH23_001569"
     CDS             56080..57531
                     /locus_tag="KRH23_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-histidine dipeptidase"
                     /protein_id="HHS5224850.1"
                     /translation="MGNVLEGLKPESVFKNFEKISQIPRGSGNEKGISDFLLSFGKNL
                     GLETIQDESLNIIIRKPATKGYENCPGVVLQGHMDMVCEKEKNVEHDFLKDPIKLRID
                     GDMIYATGTTLGADNGIAVAMGMAILEDNTLEHPALEVLVTVNEEDGMNGADALDPSL
                     IKGQYILNMDSEEEGYLLVSCAGGKTCVVSLPVEYKEVKGDKQGLLVEVTGLLGGHSG
                     MEIVLQRANANKAIARVLSVLNVDYELASVDGGTKHNAIPREAKCVIAVNKADVESAK
                     KQINDILTAFKHEFTTSDPGMTYSVAETSVDKVLTKDCKEKVVQMSCLTPHGVQSVSL
                     DIEGLVESSTNFAIIETKESTIEFLTSVRSSVMSIRDEIADRIRLLAQALGANYDLIA
                     QYPAWEFKKGSKLEKICSETYEKLTGKVPTVMALHAGLECGLLLDKLPHAEAISIGPD
                     MFDVHTPNEHVSIPSVANVWDYVIEILKSMNQY"
     gene            complement(57735..60248)
                     /locus_tag="KRH23_001570"
     CDS             complement(57735..60248)
                     /locus_tag="KRH23_001570"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase domain-containing protein"
                     /protein_id="HHS5224851.1"
                     /translation="MEDCVVNLKKLLLLIIVITSIFTSCIFSFGINAIGNDNRTIRVA
                     YPIQKGLTEIDEQGNYFGYTYEYLLEIAQYTGWNYEFVQVPGEINESITKLMKMLENG
                     EIDIMGGMLYNEPMQKIYNYAGNSYGVANTVLQALYENTDIDNIMSSQDVKKIRIAVI
                     ENSDTRLKELDEYCKMNLMSPELVYCKTNDEQLEALKSGKADVLLNVSMNPLEGVRTV
                     AKFSSKPFYFITPKGSTNLTQKLNSAINNIEQKDPYFSTTLYEKYFTPENNQMFLSDE
                     ETDYIKETEKLKVGVLLNKPPFQNIDKDTGELRGISIDLLNHICDKTGLEFELVPVKS
                     QEDLENMTKKREIDIVAGMIYDYEYSREHNIVMSRPFLSTQYTMMINNKLNENSLDGK
                     RVALAKGINYYGQFEENIVWYDNLEECIEAVNKGYADYTYGEGYSMQYYMNQPKYKNV
                     RLVPQTYKAKSICFGIIKKDKQELLNIFNKAIISISSEKMQSIVYQNTTYRQDFSLLY
                     IMQQNPIETIFIVASLLICIIGFMAFGLHTRTSMNEKISLELKKHTQLYEMTSEYFFE
                     YDYKQDKLIISMPEKGIETYYGLDKNDKESENGNIENERDKIRKEYNKKFFDVIKSQE
                     NGTTEMYSIMLDDTFHWIRVTSKIIYNDRKIPMYVIGKICNIDSEKEEKNRLLDKAQR
                     DSLTNIYNAAYIRKLTAQNLLNLSTEKNGALLIIDIDYFKSINDTYGHLLGDKVLIDV
                     AKVLDESFAKNDIVGRLGGDEFSVYINDIINKEELINKCNDVYNHIHLIKLPNGESLS
                     ISMGVVIAKPGQEYDELYQIADNALYDSKRQGRNRFKIV"
     gene            complement(60471..61292)
                     /locus_tag="KRH23_001571"
     CDS             complement(60471..61292)
                     /locus_tag="KRH23_001571"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HHS5224852.1"
                     /translation="MIDINLEKCVGCGMCESDCLVNAIKVKDDKAKVKNILCINCGHC
                     MAICPTDAIEMQGFDKNEVIEYNRESFELEPEKLLNFIKFRRSIRQYKDIEVEEEKIK
                     NIVEAGRYTPTGGNRQPIRYILVKEKLKEVKELAIQGLYNLALDTDDNDPVRSIYKNT
                     FKKMYKRYKENGNDSLFYDAPLLMVVVGDMSLGGSAYVDGGLAASNMELMAYSQGLGI
                     CYNGFFVMASNVEPKIKELLGMSENEAVITSFILGYPDVKYKRTVNRNTAKFEVR"
     gene            complement(61810..62286)
                     /locus_tag="KRH23_001572"
     CDS             complement(61810..62286)
                     /locus_tag="KRH23_001572"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016818 - hydrolase activity, acting on
                     acid anhydrides, in phosphorus-containing anhydrides
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HHS5224853.1"
                     /translation="MKLTTICYIEKDDKTLMLYRNKKKDDIHEGKYVGVGGKFEQGET
                     PEECVIREVKEETGLTLKSLSYKGLITFPKFKDEEDWYMFLYFSDEFEGELSEKDLND
                     CKEGNLIWVDNDKIFDLNMWEGDRLFLNWAKTGNIFSAKIVYDNGKLKDYNVSFLD"
     gene            complement(62320..62898)
                     /locus_tag="KRH23_001573"
     CDS             complement(62320..62898)
                     /locus_tag="KRH23_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HHS5224854.1"
                     /translation="MREEALEILFKYLETDRMRKHCYAVEAVMRELAKRLEPEKEEEW
                     AVAGLLHDLDSDIVGRKPGEICEGHATTTVELLKKENFGDEEMYRAILGHHDGMGVTR
                     TSLMEKAIYAADPITGFITAIALVYPDKKLTSVKTKSVIKRMKETRFASNVNRDAMRS
                     IEDIGIPFDEFAELSLNAMKNISDVLESAENN"
     gene            complement(63002..65602)
                     /locus_tag="KRH23_001574"
     CDS             complement(63002..65602)
                     /locus_tag="KRH23_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3656 domain-containing U32 family peptidase"
                     /protein_id="HHS5224855.1"
                     /translation="MKKIELLAPVGSFDSLKAAVQNGANAVYLGGKDFSARASANNFD
                     RNELIEAVKYSHIRGVQVFVTVNTLIKQYEIEDFVEYVKFLYDIDIDALIVQDIGMAR
                     LIKKLLPDFELHASTQMVAHSLEDVKYLQSVGFDRVVLARELNVDEIKWICENTTVDI
                     EVFVHGALCVCYSGQCLMSSMIGNRSGNRGRCAQPCRQKYELIDINTGEVVKSNGDYL
                     LSPRDLSTIEDLDKIIEAGVLSLKIEGRMKKPEYVATVVSGYREAINEFVDKKKISIS
                     EEIINNLYTIFNRKFTKGYILGEVGKDIMNSNRPNNQGLYIGKVLDYNRKNKRLRVML
                     ENTLKKGDGINLGGGTIGRIIKDGEITTIAHKGDLIELDFVGEAKRNQLIYKTSDSEL
                     MDRVQATFQQDKEFIKTNIRAKVSIKLGKKPELFISDFCGNKSVVEGDKIVEKAIKVA
                     LSKEKIETQIQKLGNTPYKLKEIEIDLDEGVSMPISVLNQMRRDCIELLDEERIKIKD
                     RKFKKNRLKYQPNRVNKQKKLDTAPKIRVKVKNLEQLEAVLNYNVDLIYYEDINTLSK
                     ALQMVSSISIDSNISIDSSISMDLDTSSSLGTPKELMGSNTNNIDTLSNTSKIDTLNK
                     NHYNTAVTDKKLIYSAPRIVRNKEYKQFEILDNIKGINKVQIGNWGSMEYFKKKDLNI
                     DCYLNAFNSESINHFKEEGASTVCLSQELNLNEIKQTLKYTDVEIEAVIYGYAPMMVT
                     EYCPMGVVVRDCKKDKRVAKCKESSYALRDFTDASYRITQDIFCRSTIYNSKVTCMLD
                     NLYELEEIGIDVFRIDFTVEDSEMVKKVIEAHIEVLSNNYKLGKKATDLYKKLDEIGT
                     VAGHYYKGVE"
BASE COUNT        20385 a        12375 c         7189 g        25921 t
ORIGIN      
        1 ttactataaa agttaaattt ataagcttac ttgttataaa aataactttt ataatttatt
       61 tcaaaaaaaa tattgatttt tgtgtcgcat tttgttataa taaattaagg ttatccccct
      121 ggtaacccta gttagttaat atatctattc ccaataccct ttcataagga tatattttat
      181 atttattaaa aatcggatta gtaacggaaa ttaattcggt ggaaaaaaag agcttacccc
      241 gagctctttt tttttctgca aaaaatcgta aaaataaagt taatattaat ataactttaa
      301 ttttaaaatt aatattaacc atcactaaaa aaggatgtat tgaatttcta atatcaataa
      361 catccttttt atatattata gcacttttgc taaaaacgct tttgttcttt catgttttgg
      421 atttccgaaa acttcttctg gagtattatc ttcaagtata cttcctccat ctataaaaat
      481 aactctatct gcaacttcct tagcaaatcc catctcatga gttacaattg ccattgtcat
      541 accttcttta gcaagttctt ttataacatc caaaacttcg tttaccattt ctgggtcaag
      601 agcagatgtt ggctcatcaa acaacatcat atctggttcc atagcaagtg ctctagctat
      661 tgctattctt tgcttttgtc ctccagataa ttgtgatgga tatgaatctt ttttatctaa
      721 aagaccaact ctactcaaca aaatttctgc ttttttttct gcttcttcct tagtcatctt
      781 ttttaattta attggtgcta atgttatatt atctaaaata gtcttatgtg ggaataaatt
      841 aaagttctga aacaccatac ctatattttg tctaacctca tcaatattag tttttttatc
      901 gaccaaattt tttccttcaa atattatttc tccacctgta ggtatttcta gtaaattcat
      961 acatctaaga agtgtacttt taccagaacc acttggacct actataacca ttatttcgcc
     1021 tttagcgatt tctaagtcta tattttttaa tacatttaaa tctccaaaag atttacttaa
     1081 attttttatt gtaatcatat tatcactttc ctttttacta ttctatgttt tccctaaatg
     1141 ctaaacatgc tctcatctag ttagacacag atagtttctt ttctaataat ccaactaatc
     1201 ttgatagagt aaatgttata acaaagtaaa ttgctgctgc tactattaat ggctctaatg
     1261 ctctaaatgc tgcatttttt actatatcag cagtacgcat tatctcaaca actcctatta
     1321 cagatattat tgaagattct tttacaagtg taataaactc atttgctaat gaaggtaata
     1381 tattttttat agcttgaggt attattatat atctcatagt tgaccaataa tttaatccta
     1441 atgatctact tgcttccatt tgtccattat caactgattg tatacctgat ctaagtatct
     1501 ctgccacgta tgcaccagag tttactgata atgcaaatgc actagctata aattcacttg
     1561 gtataccaaa caacataggg aatcttattc ctaattgagg taaaccaaac catactatat
     1621 atatctgtac taataatggt gtccctctta aaacctcaat atagattgat gatattgctc
     1681 ttaatacttt gctctttgat atttttgcca tacagataat tatacctatt ataaatccaa
     1741 agcataatgc cacaagagaa attgatactg tcacacctgt tccttccaaa aaagaagtcc
     1801 caaatctact taaaaaacta aaatctaaac tcataatttc atctcccaca taactttctt
     1861 actaatttga agcagcttca gtagatgctt catttaaaaa ttcttctatc ttcttgccat
     1921 cttgtaattc ttttatcttt ttgtttaata attctataaa atctttgtta ttgtcagatt
     1981 ttttgattgc tgctgccata ccttctgtta catctttccc aacttcagta tttgccattt
     2041 ttattccatc atatttttta acatttatta aagaaactgc ttcattagta acaactgcat
     2101 ctatgtttcc attttttaat tctgtaatta aatcaggtat tgctttcaaa gattttgtag
     2161 ttgtcatttt taaagtgtta actacatatt cttcttggat acttcctgct tgaactccaa
     2221 ctctaagttt ctttaaatca tcttcagttt ttactttgtc tatatctgca tctttaacta
     2281 taactgcatt tctacttaaa taatataatt ctgagaaatc aacactcttt tctctctctg
     2341 gtgttggaga catacctgca agaacaatat caacttggtc tgcatttaaa gcacctatta
     2401 atccatcaaa tgacatatcc ttaatttcaa cctttacacc aagctctttt gcaaattctt
     2461 cagccaacat tatatcgaat ccttttattg aatcttttcc atctactacc ttatgaaatt
     2521 caaatggagg aaattctgca ctagtaccaa caactaattt tccattgtct tttatttgtt
     2581 ctaactttgt tttttctcct ccaccactac atcctactag cgataatgtc aatcctaata
     2641 ctaatcctaa acttaataat tttttaaata ctttcatttt aactacccct ctcttttaat
     2701 tataatttcc ctcagatttt aatacttaaa tgtttcgagt tacaaaaaaa gtctctcagt
     2761 ctttaatgac taagagacga ctttaccgcg ttaccactct tattgataaa tacttatatt
     2821 actttcaaaa tttgtgactg ttagctttta agctgtatgg atatttttat tttaaaatca
     2881 aaaaagtccc ttagctttac agctaagaga cgaattatat ccgcgttacc actctttttg
     2941 ataagtaagt acttatcctc tcaatccctt aaggcgggta aaccaattat catactaaag
     3001 tttctaataa tctcctccag agctctcttc acatagactt cattgttagg cttacaccaa
     3061 cccctaactc gctgtaaatc catatatgct actttctcta tcattggatt tgtttcctta
     3121 aattgttaat acaattgtac ttccttataa tatttttgtc aataagtttt ttattttttt
     3181 aataattttt acttgtaaat tatctaaata ctactgttta tatttattga tattatttgt
     3241 gtaattataa atagtatatt tcatattttt agctatttct taaataatac taaataatat
     3301 ctttcacatt gttgcttttc tttaataata ctaaataata ttttccacat tgttgctttt
     3361 tctaaacaac tataaataat atattaaacc cttatttctt tttctaataa gttaaataat
     3421 acattttaca catatctatt tgccttgcac ataataaata atacattata ttcctatcta
     3481 aatttagatt ctaaattaaa tagtataaat tatattcttc aataaacaag ttttcaaatc
     3541 caagattcgc tctctatctt taaactttat tgtaaacata attccatctt ttttaattat
     3601 ttctccttca tgaaattttt tatggtatac cttatcccct acaccaatac tgtcaatttc
     3661 ttttttcgtt ggagatttta tatcattaat aaataatgat ttatcaactt tcttaccata
     3721 cttatttaaa gtagagctta tacataactt ttcttcagct cttgtaatag caacatacat
     3781 aagtcttctt tcttcttcta attgttcttc ttttttctct tccttacaaa tatcatatga
     3841 tttttcatga ggtattgttc cttcatttac acctataata taaacatttc taaattctaa
     3901 tccttttgca ctatgcatag ttgtaaatat gacaccctca gtctgcttat tcttgttatt
     3961 ttccgttaac tcagtcttta ctctatcaat atgctctaaa aactctgtaa cagtattaaa
     4021 attagttgct gaactctcaa gttcatttaa tatctctaca agtccattag tctttatctt
     4081 tctgttgcta caataatcta aaacatatct atcataatca agactagttc taatataaga
     4141 tattgcattt ttaggattta aagtatttaa ataacttaaa tctatttcca aatcatttat
     4201 tgttttaact tgtttaggat gaagattaca cttatttatt aatgctgtta taaagtcatt
     4261 ttcatcctta accatattta tactgtcttt ggatatatat ctaaaaggct tgtttataat
     4321 tctcaaccaa tctttatttg attttggatt aatacctatt cttaaatagg ctagtatgtc
     4381 ttgacttgcc caatggtcat atattgtaat tactgagtct tttactacaa atggaatcct
     4441 catatccata aatacatcta ctaatgctct tgactgtata ttagttctat aaattactgc
     4501 aaaatctgaa tactctacat aatttttttg tatttcgtca attatttccc tggcaatata
     4561 taaggcttct tcctctgaat catgcggaga aatataggta acacttcctc catccccctg
     4621 actacactta atgatttttt catatctatt tttatttttg tcgataagtc tatttgcagt
     4681 atgcactatc tcacttttag acctgtaatt tatatctaat attatttttt tagtattatt
     4741 aaagtattgt tcaaattcaa gcaaaaaatc tggtctagca cctctaaatc catatatact
     4801 ttggtcttca tctccaactg caaatatatt gtttaatggg ctacaaatta actttaaaac
     4861 ttcaaactgt actttattta tatcttgaaa ttcatctatc aatatatatt tatacacatt
     4921 tctaaccatt tctagtgcag acttattgtt caaaagtaaa taataagttc ttataagcat
     4981 atcatcaaaa tctattttat taactttaga tttttgttct tcgtataagt tgtatacttt
     5041 taaaaactca tcttttgtta atacttctga attaaattca tttttatcca taagttcatt
     5101 ttttacatag gaaatttcat ttataacttg tcctatattc tcatcatcat cagcattctc
     5161 tatatttaaa ctttttagga ttgccttgat tgtcattcgc tttgactttt catcaaatat
     5221 actgtctaag ttgtatcttt caaagtatct tagaatttta aaaaatacag agtgaaaagt
     5281 accataggtt accttattaa gtcttatgtc atcacttaaa ttcaaagctc tatttttcat
     5341 ttctattgaa gatgccttgg taaaacttat tgccaagatt cttgttggtg ctatgttttt
     5401 gtttacaacc atattggcta ttctatatgt aattactctg gtcttacctg aaccaggccc
     5461 tgcaagtatc atgcaaggcc catctatatg ctcaactgct tctaattgat tttcatttaa
     5521 ctttcttata tctatatttg ttgtgattat tagctccacc accttgattt ataattatat
     5581 tattttcttt ttaattataa actaaaagtt cataaaaata aatttaattt ttcctctatt
     5641 aaaccacatc attcctattt tcatgacata tcttgagttc ttttttaatt ttgtcgctta
     5701 tatcttcagg tataaatgat ggtttactaa tatagtagcc ttgcatataa tctactccaa
     5761 gattaattag tgtttccatt tcaccttttg tttctacacc ttctgctatc actttaatat
     5821 ttctttcgtt agaatatgag ataagatttt ttaatatttt ctgtctgttt tcatctttat
     5881 caatacctct tacaatagac atatcaatct ttacatagtc tggcattata tataatagta
     5941 cagcatctcc gttgtaacct gtcccaaaat catctaaagc aatttctata ttccaatggt
     6001 ctatatatgc tttctttttc tcaataaaat cttcattaat cttatcattc tctgttattt
     6061 ctagtactac tctatttaaa tattcaccat ataaatcttc aatttcctca aaatctactt
     6121 ttgacaaatt attattagga atagaattta agaacagttt gcaatcgcca aatttttctt
     6181 tgtatttttt aaatgattta agtgctttaa accatgtaat acgctcaatt tgatataatt
     6241 tagactgtga acgagctaat ctaatgacat ctattggtga actaaaagtt tttattttag
     6301 gtctcataag tgcttcatat gcaaatactt tacctttaca atctacaata ggctgaaatg
     6361 catactcaac taattgacca tcaattaact tgtttaattc ttctctatta ctcaataaga
     6421 atgaatcctt attatatata ttaatatcaa attcactaac ttcacccttg attgtatttt
     6481 taatttgata catagcaaaa tctgcgtatc tcattaattc atcatagttg gttgagtcat
     6541 cagggtacca ggaaattcct gctgatgccc ttattttaaa ttctgttcca tcatgaagtt
     6601 ttaataaggt attattcatc tgtttcttaa cagaattaat aatatctctt atactatctt
     6661 tgctttcata tccatatata aatacataaa actcatcacc tgaaagtcta gatactatac
     6721 cattccatga tataaacttc ttaagtatgt ctgcagcaca cctaatatat tcatcaccag
     6781 catcatgtcc atatgtatca ttaatatatt ttagattatc taaatcccac ataataaatg
     6841 ctgctatctt aagttcatct ttattcttaa atttttcttg tatctgtgaa tgaaaagctc
     6901 tcctatttaa aagattcgtt aaaatatcaa aatctctttc atattctatc ttccttttct
     6961 caataaattc ttttgtgaca tcaacaacaa caccaagaac ctttagctca tcttcaaaga
     7021 tattcattct tatccactta agttttttat ctttagattc aaacttatat atatatgtat
     7081 tttctgtttc ataactttct tgcaaatatt tatctagtcc ccttaatttt ttcaggaact
     7141 tatttttttc catatatcca tattcttcaa atttgatttc agtagtaaac acgctaaaaa
     7201 attcttttgt acaaaaaaca ttctctgcgt ttttgtataa ctcaaaagcc ccaattggca
     7261 tatctaccat ttcaataatc tgtgataatt ttgacgaaga atctgcaaca tttgcactga
     7321 gcaactctat agctgaagat aattcatcta tttcagatat atttatctta tcaagattta
     7381 ctggttttga tggattactg tttctaactt tgttggctaa aagaacaatt ggttttgtaa
     7441 ataatcttga tgcaatgtaa atacctatta gacctattaa taaagaaatt gctatagata
     7501 ttataactaa tttctctacc ctttttgaaa atgacaaaag acttttttct tcaataatac
     7561 ccaaaagagc ccaacgttca ttttcaaatg gagtattgga gttatataaa tctaagtatt
     7621 gtacactagc ataaatgttg ccattaccac attcattatc tttattttta atcttatata
     7681 tatttttata cgattccttc tgctctaaat tagaatgtaa accatcccaa aatttttctt
     7741 ttaatgagta tccatttgaa attacatttt caaaggccat atcattattt ctatctacac
     7801 ctaaaatata attacccttt ttattcccat ttatctctga atatggaagt aattctctta
     7861 aataatttac acttaaatct attccaagta ctccatatac agttccatct tcataaataa
     7921 ggggaactgt atatgtcata agcctatcac ctgcatttgt caataaaaac ttacttcccc
     7981 agtatcctaa attagaactt gatacatttg gattatcaat tgcagctcta aatggtttat
     8041 aaaaaaaatc atctccatct tgctcatttt cacttttaaa tgaaaactta ggttcccaat
     8101 aactgtccat agatattcca aaacttcttg ctatatctga tgaacctctc tcaattaaca
     8161 aatcagaatt atcatttgga ttaaacttag ggtctaaatc ccttatatac aatcctgtcc
     8221 tacttatttc acctttacta tctattgact tatcgttaat atttttgtca cttaggatta
     8281 taaaagctcc tgtaacagaa ttttttctca aaagatatat taaatcattt gatatgcttt
     8341 ttataatatc tttgttaatt tcttcattgt tgcctacatc ctcaattaag gcattttttt
     8401 catttaatac tttttttaca gaggaattaa ttgtagcttc cgtttcactt gtatttgacc
     8461 atctttgtaa catttcattt tgtatataat ttttacgatt aattactctt tcatttaaga
     8521 tgtcaaacga attatcattt aatttcttaa tagttcctcc ccataaaatt gtggcacaaa
     8581 ataaacttgt ttgaattagc ataacaataa ttaggggaaa tatcatcttt ttcattattg
     8641 aattgttttt tcttagattg ttttccatac ccattccacc tatacctttg tgctcgtcaa
     8701 cacactaact gccaattcat ctattttttt atagcatttt caagctcagc cttaaaactt
     8761 tcaaaccaag ttttaaaatt tttatcatta ttaaattgtg ctactgcatc cttcttagaa
     8821 gttccacttt ttactaattc atttatttta tttgaatctt ctttagcttt atcaagcatt
     8881 gaatattcaa gtatttgtct agctttagtt ccaccatcaa atgctttatt agtatataaa
     8941 ttacaactgt taatctgttc aatagatgag gctattgaac cttcaacttt atcagataaa
     9001 ctcaaattat ctttcttcat aacttctttt ataacatcca aatcattcgt ttttttcttt
     9061 actggtaagt atccagaagc aatagagaat tttatattag gttctttatc tgtaaaccat
     9121 tttaaaaatt ctactgatgc atattcttct tctttagtag attttgttac agccattcct
     9181 gcaccttgtt gtacagcata ttttccttct cctttaaaac gtggtgcttg aaaaacagat
     9241 gtttcaatat tataactctc attatcattt agcattactc tatctggaaa gtatgctgct
     9301 cctgaactag aacctacaag agctaatata tcacctgttt ttgcatcatc agaacgaaac
     9361 ttaccataag aagcaaaata tccatttata tatggtacat agaaattatc ccatagtttt
     9421 ttcataactt tttcatcaat atttagtgta actttaccat ctttaacaga aaaaatttct
     9481 actcctagtt gtttacttcc tataataata taatttgcta aagcatctct tccaaaaaat
     9541 gctttaccat cattaggctc tttcgttaaa ctatctgtcc attcataata tttttttgat
     9601 gtctctacta atccttcaat tgtttttata tcatttatat ttgaatttgt agcttttgca
     9661 aatttatccc aatcagtttt atttaacatc aaaatttcag ttgattttgc aattgggaaa
     9721 agtttaaact catccttaga atttattctg ccttcttcta catattcgtc tatgtattca
     9781 tttaattctt ctttacttat gtacttatcc atatctacta gtaaccctaa tttatccatt
     9841 tcatatgcag tatctgagta tgctgcaaat atatttggta catcttcaga accaactttt
     9901 ttatttgcag aatctaaaac tttctctgat aaatcaacta cattaccttg actgaatgct
     9961 tcaacaataa ttcctttttc agcacctaca gtgtcattaa attccttaac aagcttatca
    10021 aaagccattt tctgctgtcc attataataa tgccaaattt gtattgatgt cggattttct
    10081 gggtctaact tataattatc ttccttcttt aaactacatc ctgtaagtaa taaaacaatc
    10141 attgatgtga taattaattt tgcaaactta cacctattca taaaatctac tccttcaaat
    10201 tataaaattt ataatagcat taaaactgta acttcactat ttatattaat tatagaacgt
    10261 ttattgatat atttaaacag gatttacaac atatttaaaa gcaattaaga aacatactat
    10321 tacaaatata gaaaataaag cttttacata atttttattt ctaaatgcac caaatgacac
    10381 caatccttgt tgaatagcta ctgtaattac taaaagtatc attattatat taagttgaac
    10441 cagtttaaat aagtaaagta atgaaaacac tactaaaagt acacataata caatactaga
    10501 tttattaata atatcatcaa tcttatctac cttcttagat tgcttattaa ctttatttaa
    10561 tttttcttta tttaaattct caactttttt attatacctt tctcttgttt tatctttata
    10621 tttagtattt ttatttttat ttcccattta ttttccatcc tctataaatt ttttaattga
    10681 gcttatacat tatttaaata ttatatattt aagataccat atattcctac aaaaaggtaa
    10741 cttactatgt atctattttt gattttcgca taaaaaagcc atctccttta gaattaattc
    10801 tgtattgaga cagctaattt aactatttat cctttgaaac attttctaca ttatcatatt
    10861 tactatcaac taaaactata tcaactcttc tattttttga cctaccttct tcagatgaat
    10921 tttctgctat tggtctaaac tcaccatatc ctacagcaga taatttatct ggtgctatac
    10981 ctgcattgtc aataagaagt tgaacaacat tggttgctct cataactgat aaatcccaat
    11041 ttgacttaaa ctctgaattt tttatagaca tattgtctgt atggccttct actctcatgt
    11101 aactattcat ttcatttaac atcttaccta tttgaataat cttatctcta gaattatcct
    11161 tcacaatcgc tttccctgta tcaaatagta ttgtatcttt aaggcttatt actaatcctc
    11221 tatcttgaac tcttaatgat actgaattag ccataccatt ttcgtttaaa tacttctgga
    11281 tttcttcacc aattttttta aacttagcat tttgtaaagt atctaaatca ttacttcctg
    11341 cttcaactac tggttctatc ttgctattac caccttcaat aactccagaa gaaccaccaa
    11401 aagcagaatt tagagattga gataattgtt tatatttctc cgcatcaaca ttactcatag
    11461 aatacattat tacaaagaaa atcataagta atgttatgag gtctgaataa gttaaaagcc
    11521 atcgctcatt gttttcttct ttttcatctt catcatacaa cataaacatt ccatcctttt
    11581 atattattca gctctaccac caatttcttc aagttcaatt agttcttttg aatttaaaaa
    11641 tatttttaat ttttctgtca ttaaattaga attatcaccc tcaagtatgg ataatattgc
    11701 ttctatcacc aaaagtcttt cacttacttc ttgttgattt atagccttaa gttttgatgc
    11761 tattggtaac catattaaat tggcagaacc aacaccatac aaagtagcca aaaatgcaac
    11821 agaaatttga ggtcctaatg catctggatt acttgaaaga ttacctaaaa tatgtactaa
    11881 tcccataact gtacctatta tccccagtgt aggtgcatat ccacctgctg aatcaaaaat
    11941 tgctattcct tctttatgtc gttttgatgt tatctgtatc tgtgattcca atatatttct
    12001 tatagtaact gcatccactc catctaccat aagttcaagc ccttttctaa taaaagggtc
    12061 taattcatca ttctcactta tttctttgtc aatactaaga agcccctctt tcctagcctt
    12121 tgttgcaatt tctttgaaat agattatatt ttctatgtta ttaggctttt tatttttaaa
    12181 agctaataac attatcttta tagacttttt aaacacaggg aatggagtcg aagctccaac
    12241 agctcctata gttccaccaa acacaacaag tgctgatgaa aatacaaata atgctccaac
    12301 atgtccccca tcaataacaa aagcaactac caaagatgct atccccacta tgaaaaaaat
    12361 taaagttgtc atctattccc tcctttcttt agttatacat atctaatcat ttatgacatt
    12421 ataaaaagac tatctttaat aaaaatagcc tttaataatt ggcggagaag gagggattcg
    12481 aaccctcgca ccggttaccc agcctaatcc cttagcaggg gatcctcttg agccacttga
    12541 gtacttctcc atatctctat actagtaaat tatataataa aatcatattt tagtcaattg
    12601 ttttataaaa tttgagttat tttgaattat taaacatcta tttttatttt tttgcttaaa
    12661 tgtaagtttt aaatatggta aaattatctt gcataacact tataatatta tttgataaat
    12721 atacatacat taacaaatat acctaaactc tgacttaatt gtaagttatg ccaaaactaa
    12781 aataatacta gtccaaggag gatattttat gttaccacag gaaagatatg agaagatttt
    12841 aagtattctc aaatcagata atataattaa aataaatgac atagttcaaa tgtttgatat
    12901 atcaatagaa actgcacgaa gagatttagc ccatatggag agtatcggtc ttttaaaaag
    12961 agtttatggt ggtgctatac cagttatagc aagtagcgta gaacttaact atgttaaaag
    13021 aaaaaaaata aactcaaacg ataaaaaaca gattgctatt aaatgtagtg agtttataaa
    13081 tacaaatgat actattttta tggatactgg aactactgta cttgaagttt caaaaaattt
    13141 gaaagataaa aagaatctaa ctgtaataac caactcaatt ttagttgcaa acgaacttat
    13201 gaatactaat ataaaagtat atgtgcttgg gggctatctt agagaaactg aaggttcttt
    13261 ttctggtccg cttacactgt cagctattga acaatttaat gttgataaag ctattttagg
    13321 cgctggaggt atcactcttg aaaatggaat ctctgactat cacttagaag aagcacttgt
    13381 tagaaaaaaa atgattgaaa ggtctagaaa atctatagta gttgtcgaac ctcctaagtt
    13441 tggtataaat tcatttgcat cagtagctcc tatagaacat atagatacta ttattacctc
    13501 tgctagtata gaccataata taataataga gttttctcaa aaaggaatac ctttagtcat
    13561 agctgataat tagcttatat gattgatttt tagttccttg atgtaataaa ttaaaattaa
    13621 ggagccaaat aattatttat ttagctccat ttatgtctaa actatacttt atattttaat
    13681 tatgtaacta ctttcagtta gcttatcatt tttagttatt tgattgccat tttatttaat
    13741 ttataagttt tagttattcg attatttttt aattgtctgt ctttttaatt tatttttagt
    13801 tatttaaact cctactttaa aataatttaa atttgactta agtattgttt attctacact
    13861 gcatctttct tcattttaat actttgttct tcttccaagg ttaaatcttt tgtcataagt
    13921 atagcaagtg caattgccaa tactcctcca accaattttc caattacaac aggtgtaatc
    13981 atctctggaa ctactcctgc tgtaaatcct aaatggtccc ccaaagctgc tgtagcacaa
    14041 accagccaag cagtatttac tactttcccc tttggactca tatctttcat cattttatat
    14101 actggaatac tattggctaa agtaaaaact aatcctgctg cactagtggc atccatacct
    14161 aattttccac ccactattgt aagtggttta ttaagaactt taactaataa atgtaatatt
    14221 ggaaaagtac ctaataacac gattgcaata cttccaatta cttgaatacc ttctcttata
    14281 ggtgtcatgc cttttataag tactatacct gttatttctt gaaatgctgc tgctcccaaa
    14341 cctatcgtta tcaatataga tataaatttt ccaaaaacta atgacccatt tatcataagc
    14401 gtagaattaa attttaaacc tactgccaat attactgcca atattatcac tggtatcata
    14461 tttataatta ccattgataa gttaaatcct gctattaatc ctcctataat acctccaaaa
    14521 ggtattgtta tcaagcctat cagtaaccct tttgcaaaga atggtctgtc ttcatattct
    14581 ataagaccta gtcctactgg aattgaaaat actaatgtac atccaagcat ggatgacaca
    14641 accaatcctg caagcattcc tgcctcttta ttgtgtgcaa gttccatagc caatggatac
    14701 cctcccatat cattcgctaa aatagttgca aacatagatg ggtcagctcc acagagattg
    14761 aagattggta ttattatagg acctagtaca tctgaaatta ctggagctaa acaaactata
    14821 ccaaccattc ctaaagccaa tggacccatt gaattaaacc cttcttcaaa ctgctcgcca
    14881 agtccaaatt tatttccaat tattctatct aacgctccta aaagcactcc cacagccatt
    14941 atgtataata taattttatc aaagggcatt tttaattcct cctatacatg taaaatactc
    15001 tattgtaact taattagcac acaccttttt ggtatcgttt tcccaattca tagctctttt
    15061 tactgcttgg ttccatccaa gtaatatttc ttctcttttt tgagtagtca tatttggaat
    15121 atattttttg cttattgtaa attcacttct aatttcatca atactgttcc agacaccaca
    15181 agaaagacct gccatatatc ctactccaag tactgtcgtc tcaggatttt ctgcaatttc
    15241 aattggtata cctaatatgt cggattgaaa ttgcattgta aagttatttt tagtaattcc
    15301 accatctact ctcaacattt ttattttttt ccctgaggct aagttcatag aatcaacaac
    15361 atctttgact tgaagtgcaa cagactcaag agtcgctctt actatatgct cttttttagt
    15421 acttcctgtt atcccaacca ttgtacctct agcatattgg tcccaataag gtgctgctat
    15481 acctgcaaat gctggtacaa aatatacacc tccagtactt gatatggaat ttgccatgtc
    15541 atcagtttct gaataatttt ttataactcc aatgccatct ctaagccatt gtattgcagc
    15601 acctgctata tacactccac catcataagc atatgtaact ttatctccta ttttccaagc
    15661 aacagttgtc aaaataccat tacctgctat atttagttcc tcacctatat tcatatatag
    15721 gaaacatcct gtaccataag tatttttaac cattcctggt tcaaaacatc cattgccaaa
    15781 taaagctgct ggttggtcta ccattgaagc agtaattttt atagaaaccc cacaaaatgc
    15841 ctccttatct gtagttccaa aatcaccact cgtaggcatt atatctgcta aaatacttct
    15901 aggtactcct ataatgtcaa gcaactctct atcccaatcc atatctctta tattaaaaag
    15961 cattgttctt gctgctgtcg atacatcagt taaaaaagat tttcctcctg tcattttcca
    16021 tattaaccaa ctatctaatg ttcctgcaag tacttctcca tttttaattt tttcttttac
    16081 accttttaca ttatctatta cccatttaat ttttgtacct gagaaatatg ggtctataat
    16141 taacccagtc ttatctatta tcttattttc taaacctggt atattcttta aattttccac
    16201 ataatcataa gttctcctgc actgccacac aatagcattg taaagtggtt tacctgtatt
    16261 tttatcccat aacattactg tttcaccttg attatctata ccaattcctt ttatatcact
    16321 ttcattgatt ccattttcaa aagcctgttg taatacatta ttactcacag tttttgtatt
    16381 attccaaatt tctatagggt catgttcaac atatccagat tgtggatata tttgagtatg
    16441 ttccatataa tcgctaaaaa caaactctga tttttcgttt atcaatactg ctcttgttcc
    16501 tgttgttcct tggtcaattg ctaatacata tttcacttta aatgtccccc tttattttca
    16561 gaattaataa attctttttt attttttgaa tatataatct attcaagtta tttatatttt
    16621 atatcatcat gtggatttat gcaatattca ttacaatatt ttttgttatt tttaattata
    16681 gtgattaaaa aagtattttt attgaaatat tgttgcaata tttattattt tattctataa
    16741 tctagttaaa ataacacata atattttaat atttacacat aatcagtcat tcaaaaattt
    16801 aaatttaact ttttaaggag gctttacaat gaaaaaaaca tatctattca gtcctggacc
    16861 agtaatggtt acagataaag tcagaaattc acttcttcac tatgatatat gccatagagg
    16921 aaatgagttt atggatttat tcaaagatac acaacaaaaa atcaataaac tatataatgc
    16981 aacttctaat tactactcat taattgtatc tggctctgga acatctgtaa atgaatgtgt
    17041 actatcttct atctttgaca aagaagatgc agttctgcta gttagtaatg gtgtttttgg
    17101 agaaaggcta gaagaaatat tatctactta taatgtaaaa acatataaac ctaattttga
    17161 atgggcagaa tacccggacc tagacatttt agaaaaatac ataattgaaa attctgatat
    17221 aaaagtaatt gctatggtgt tccatgaaac tagttcagga atgataaatc cagtccctga
    17281 actaggaaaa cttgctaaga agtataacaa aatatttttt gtagatgcaa taagtgcctc
    17341 agcaggtgaa tatattgatg tggaagagtt taatatagat ataataacag gtgttggtgg
    17401 taaagctctt ggagcatttc caggttctgc atacctttgt gctaaagaga gtattttaca
    17461 aaatattaaa gaaaatcaat gtaagaatgt gtatcttaat ctttataaac actataaagt
    17521 tgctaaatca tcttctcaaa caccaaatac acctaatgtt actttaatat ttgctcttaa
    17581 tgaagcttta actgagtttt tggaagatga cagtaaaata gaaagataca aagaatgttc
    17641 tgctatttta aggaatggca tggaagaatt gggtctaaca tttttacttc cagataagta
    17701 tatgtctaat acagtaacat ctgtatttct acctaaagaa atcaatgtaa atgagtttat
    17761 attagggcta gaaagggaaa gtggctatgt tgtctatcca ggaaaaggca aattcctaga
    17821 tgctaacata ttccaagtag caaatatggg agaaatatat ccagaagatt gttataaatt
    17881 cttagatatc ttaaaatcaa aattggagat aaaaaaagtt atataacagt ttgtttgtaa
    17941 aaccctacaa tatatcagta taaattaaat agactgattt ttttaaattt tcctataata
    18001 aattatattt tatatttttg tataagggtg aactataata tgtaaagttc acccctattt
    18061 caaatctttt tccttcagta taatcttttt cttttaattt attttatatt tttgacataa
    18121 ttattcttac atttaattgt tttttatttt taacacaatc gttttttgtt aaatcatttt
    18181 atattcttga tacaatcatt cttacattct attattgttt atttttgacg caatcgtttt
    18241 ttgttgaatc attttatatt cttgatacaa tcattcttac acttaattat tttttgtttt
    18301 tgacacaatc gttttttatt cagtcattta atattttcaa cacaatcatt cttacattct
    18361 attattgttt gtttttgata caactgtttt tattcagtca tttaatattc ttgacacaat
    18421 tattcttaca ttctattatt gtttattttt gacgcaatcg ttttttattc agtcatttaa
    18481 tactttcgac acaatcattt ttacattcta ttattgtttg ttttgataca actgttttta
    18541 ttcagtcatt ttatattttc gacataatta ttcttacatt ctattattgt ttatttttga
    18601 cgcaatcgtt ttttattcag tcattttata ttttcgacac aatcattctt acattctatt
    18661 attgtttgtt ttgatacaac tgtttttatt cagtcattta atattctcaa cacaattacc
    18721 ttttcattca atcaaagtaa tctttaagca ttatttttca agctcatcaa agtaattata
    18781 tacgataacc tcacctgtct ctttatctgt agtctttata atgcccttag ctccatttac
    18841 ctcttctttt gtaaattcat catctagcac aactttgaat ttatcttcct ttccataacc
    18901 ttgttgaaat tcatctctca aaattgcatt tttttctgct tttggcttca actcaaattc
    18961 aattccagat ttcatttcat caaaataatt taatactaca acctcattat tcattttatt
    19021 agttgtcttt ataatccctt tagctccatt tacttcttct tttgtaaatt catcattcaa
    19081 tgttatatta aatttgtctt cttttccata ttcctcttga aaatccctct tcatttcatt
    19141 gtatttagtt tcaaactctt tactcttgtt taattccata gctgatacat ttgtcaatga
    19201 tgctccaatt gccattactg ttaatgccat tactatacca cttttaaatt tttttacttt
    19261 catatcttac ctcctaaatt aaatgttctc aatgaaatta tataaagaaa atcctaagtt
    19321 ttacagtttc attcttgtaa ctaaaattac tattatgtaa ccaaactttt tgcttcaact
    19381 attccttaaa agttgctttt ttgaggaata gttgaagtta aataattaga ttttatctat
    19441 atttatagat ttaaaatcta atttatccat ataaataaat acttattttt gcaaaataaa
    19501 aatttttaat tactccaatc cttcttattt acttaaaatc ctatgataag aaatttaaaa
    19561 gtctttacct tctttaacaa taatttattt acttttaaca tacaaaatat agagagtata
    19621 tcaaaatcat tttactgaat attctaaaaa taagtacccc ctattagtat atatatttac
    19681 atattaaaaa aaagttttaa ataaagttat attttttaca acagttttgt aattaaaaac
    19741 atattgaagg taaatttaaa ggtactatat actataaata tgtcgacaca ataaatttaa
    19801 aaaggagaac taaatatgaa aaaaagatta ataataatga tattgtctgt tgtcttagta
    19861 ctatcaagta tacttacgat atttgcatat tcaaatatta agtataataa taataaattg
    19921 atatattcta atatgataga taaaaaaact caaaatagtg taaaggaaat cctaaaagaa
    19981 aataaaatta atgaaaaaga tatagataca tttattaaag cagtcaacaa ttataataaa
    20041 ttgcaagtta aaatacttca aaataatata aatatatcta aatctggata ttcttcaatc
    20101 aatgcaaaac aagttccata taacctagaa aaattgcaag ataattgggt gaaaaaattc
    20161 cctgattata tggatgtaaa ttgtagaata actgctttta gactttttaa agattttata
    20221 aattcaaata agaaatttac tggagactct attgacttga atgtcgactt ggacactata
    20281 atgaataata aagatgctaa atttagcacc aaagatgtag aaaaatttat taacttcttt
    20341 tctgcaatac cagctaaaga cacagatgat acaatcaaaa ttgcagaaca aataaaaaat
    20401 gaatggaaaa aaagaaaaat atcttttaaa aataataaaa atatatctat tataaatgga
    20461 tttcttcgtt atccagaaac taaaaacgta tttataggtc atacaggcat atgtattaaa
    20521 actaaaaatg gcattctatt tttagaaaaa tatggtgtta catcacctta tcaagttact
    20581 aaatttaaaa ataaagaaga tgtaaaaaat tatatgttta atagattgaa gatgtcagaa
    20641 ggtgaaattg aattacctga ccctataata atggaaaatg ataaacttat gaaataataa
    20701 ctttaaacgc aaaatagtat ttataattac taagtcaata taatagagaa ggtctataga
    20761 tttgtgtaaa tacaagctta tctacaatct tatataagaa tgtttatata aataagatag
    20821 attaattcta agtcctatta ttctattgaa ttttattatt attttattta gattctattg
    20881 ttattttact tagaacttat tattatttta tttaagttct attactattt tcaatcatat
    20941 aaatttacaa aagactgtac ataaatttat tttatacaaa cttatctaca gtcttttgtg
    21001 tgaatatatc taaataatat cgtatttatt tatttcctct gcacagtgag aatcagaacc
    21061 taaaactaat ggaatatcgt atttttttac caagtctaat aagtatccat ctatataagg
    21121 ctctttgcag tactcttttc tatttccaga aacattataa tcaagttcat aacctttttc
    21181 tttaattaac tttattaact cttcaagaat tttatttcct ttataatcgt atggaaatac
    21241 ctgattaaac tttctaacta aatttaaatg acctattctt tttggtttat gtatacctaa
    21301 atctgaattt acagctttta tcaatgtttc ataatactta ttataaacag cttcaatact
    21361 tcctaatttg tcgattaaat tttgaaactc ctctacactg taatctacac aataataatc
    21421 atcatcaatc ttaattatat gtactgataa aagagaatcc tctaattctt ctccatattt
    21481 atttaaattc gcctttatcc cttcttcgta tccttctata aaatccactt ccgacccaac
    21541 atttatcttg attttaccct catacttttc tttcaacttc ttgacatcat taaaatactt
    21601 tggtaaatct tcaatactca tacaactatc attttcagga gcagggtctc taaatccatt
    21661 tgcatacgga aaatgttctg taaatgtcat ttctgttatt ccaacatcca ttgctctttg
    21721 tacatatttt tcaaaatcat ccttacttcc atgaggacaa taaggtgaat gtatatgacc
    21781 atctttcata aataattcac tcctttttta aagaaaaaat ctaatataaa tgcataaatt
    21841 ttttaacttc aaaataatat ttttaatcat gctaattttt attatatcta atattagagt
    21901 aattttaaac tgccttttaa gtatcttatc attagtacta ttttcaactt aacattaata
    21961 ttatttttta acttaacatt aatactatct ttaaatagta atactcaata tataattact
    22021 tagcatcaaa taactcaaat tgcttgatga ggcttttgca gtatttaaag aatatataat
    22081 tatctaacat taaataatcc aaccttgtaa taaaatttac tcattaaagt atattacaga
    22141 aaatacctca aaataaactt tttagttcat gatatactct tttttgcatg aaattagata
    22201 tatttttatc atttcaacaa tgaaagggag gcttatatcc atctttagac aaccccttag
    22261 ataaaatttt taataattaa acatcacaaa atataaaaat cgcttatatc aaacgtataa
    22321 gcgattaatt atatttacat atgtttttta gcctctaaca acattttatt agcttcttcc
    22381 atatactcta tagccttttc aatactcttt gctgtttctt cttttccaat agctctagcc
    22441 ttttcaaccc actctctaaa tccttcttca tgagtttcat tgtgatttat ccaatgtact
    22501 aaaagtattt ttaaagtttt ttcatcctta gactctgatg attcctcatg actatgttcg
    22561 tggtcgtggt cgtgagcatg gtcatgtgga tgttcatgac atatatctcc atgagtatgt
    22621 tcgtggcagt ggtcatggtc atgatgtcca tgatgatatc ttacaatctc tttatcaaaa
    22681 atcattagtt attccccctg ttattttata ttaaactctt tttttataag gtttacagaa
    22741 tcttttacaa gtagtgctaa tggtttacct tctaatccaa ctaactccac attttctggc
    22801 ataataggta aaagtatctt aagtgcctca ctgtctgcaa tagcttcact tatattacaa
    22861 gtaacttctc ccatcataga attaggtatt attacagaaa taggtgcaac tattatattt
    22921 gcttttttag ctgatactac tatagcattt tcccctgtag ctcctttatt agcatgagct
    22981 ttcatcatag aactagttgc tatagaatta gtccctagtg cataaatttc tacatatgta
    23041 ggtaactctt ctctcaaaga agaaactatc tgggctccaa tacctccacc cattccatct
    23101 atcactgcta ttatcatatg aaattcccct attaattaat tttcttgtat tattatctta
    23161 tggtccatca atcttatttc tttaattatc ccatctatta tcttttgctc tcctaataaa
    23221 tccgttaaat aaatctttcc atcacaaggg tctatattaa ccacattttc cataaccttt
    23281 tctaactcat tattactttt acaaatgaaa gctgatgatt cacacatata aatctcctcc
    23341 taatatgatt tttattaaaa atcaaaaaaa gattccctta ggtatttcaa tacaccaaag
    23401 aaaccttcat gatttcagtt tttgtatatt attatacctt aagtatatca ctttaattta
    23461 tgtaaagtca attaaagtta acgcttttta ttatactctt cattcttgta tttttcatat
    23521 agttctttaa ctaattgctt ctcataatca gtcaaatcgc cctccacaaa ctcaacatta
    23581 aattgttcag ctaatccctt tactatgttt ttctgtagaa tatctatgtc tatttttctg
    23641 ccaatttcat tttctattcc acttgctttt ttagctgtaa atttcatagc tctttctttc
    23701 aattctggtg tcttagtttt tattaattta aacaattttt ctacatcaaa atccagtatt
    23761 attgaaccat gttgtaataa aacaccatct tttctacttt gagcacttcc aattaccttc
    23821 ttattattaa tagtaacttc atatgatgca tgtgcattaa aacatgcagc tgataaattt
    23881 tccctactta ttctctcgcc tctatttaaa ttatctgttt ctataccact tagattcaac
    23941 cctttaacta gaccttcact tatatatcta taagataggt tgatgctctt atcgattaaa
    24001 ggattatctt ctcctataat tatactatag gttagctcat tatcatgtaa tacagctctt
    24061 ccacctgtaa ttcttctagt atagtctata ttcatacatc tacacttatc taaatctatc
    24121 tcatcttcca atttctgaaa atatcctata ctcaaacaag ctggttccca tgtataaaat
    24181 ctaagagttg gcttattatg tcctttctta tatgcagtaa atatagcttc gtcaattgcc
    24241 atattcattg ctccttcata tgatttatta tgtataactc tccactgatt catgattatt
    24301 acgcccccat ttttagtata aatatatcct agaaatcctc tatagattta tttctcttat
    24361 tgctaaatct atctcacttt gatttaaagg tcttgaatag ttgtatatag tacttcctgg
    24421 tctttcatta tagtatggtc tattacaatc cttacaacct cttatttcaa aaggatagcc
    24481 tttgtttatg tcttttaaaa tatcattgtc aagctttata ctatttaagt atccattttt
    24541 aaacttaaaa tactcttttg gataaccttt atttatcata taagacatta actgtaccct
    24601 tctataactt tctatgcttg gttgatttat cttttccatt ttagttcctc taactggagt
    24661 aaatgcaaat aaactaattg ttacatcatt ttcctttaaa taagtatata aattgtatat
    24721 atcttcatga ctttcaccca taccaactat tatatgtgta cttattttat tgggatatga
    24781 ttttgacatt tcagttataa attttaactt ttcatcatag ttatttcctt ttattttttc
    24841 atatagttct ttatttgctg catctattgc tattcctatt ttatcaactc ctgctgaaaa
    24901 aaacttcttt atctgttcat cattttctaa ttttgcagat agtgaaattg gcatgtctat
    24961 cttaccactt atatagttta taaagtctaa aacagagtta tgtgcttctt cacttgccat
    25021 tgattgaata catattctct ttatattttt tcctttataa gcttttaaag catctaatat
    25081 ttcttctttt gaaaactctg gccaaattac tcttgataat ttatcttttc tagtactact
    25141 ttctattgat tgagaacaaa aactgcattt atttatgcat ttttctccaa tcattatata
    25201 tgctgtggta ggaggtatat cgcttttttt gtttaatatc ccaagttcta ttgctgtccc
    25261 aactgatagt ctaatcataa aacgcaacac tccttacact catttattgt catattcatt
    25321 tctatagcct tattctttgc agaccttgat ggtaatacta ttctattgac tccacacatt
    25381 atagataatt ggtctagctc ttttctatac actcctcttg gtctcataca acctagatta
    25441 atttcagtat ctggtaaatt aattctagct tcacataaaa tatctgctac cccttctaac
    25501 tcaggaggtt ctacattttc atactcagtt ccttttgttg gaataaggac tataaatgta
    25561 agcttattag gaggattttt ctgtaggtat tctataattt catattcacc ctttatttgt
    25621 cctcctttta aaccaataca tatatgtggt gctacttctg tatgttcttg tattgtatta
    25681 tagacttcaa tataatcttc tttactcttt ttcatcttat aaacttctct tattgtctca
    25741 tcatcaaaca ctaaatcaaa agaaactata tctaaatact tacacaactc tacaatgcta
    25801 tctttatcca taagacctaa atgagcattc aatctatatc cttgctcttt taagttttta
    25861 atggtattaa tatgagtatt tatagggaca tctccctcat aactacaacc gccactcaat
    25921 agaaagctag ttatattcct tgattgtact ttttcctcat attcttctat tggcaccata
    25981 ttgtttaagt agtgaccgtt gcaatgggca catttcaaac tacattgatt gcttgtagta
    26041 ctaagagcta gtgtctggtt aggataagca aactctattt tatttccaaa attctttaat
    26101 ttaatatcaa atgctatttt cattttttca gatagattct tattcatagt ttattccttc
    26161 ttaagtacat tttactcttc tagtaatttc tttgctgttg ggaactgctc tatattcgta
    26221 tgtggtaaga aacatgcaga aataaattca tccatataac ttggatatac actaagttca
    26281 acataagtta tttgattacc tatttcttca agtttatttt ttgcatcttt acttataaga
    26341 gctaagtaag aaccaacaag tgaactattc cctatataag taaatttttc tctatcaata
    26401 tcaggaagta accctataat tattgagttt tctatgtcta ggttgtttcc tataccacct
    26461 gctatataaa ccctatctaa tatactaaaa tccataccta aactatctac aagagtgtat
    26521 gcgcctgaat atatagctcc tttagctctt atgaaattat ctatatcaac ttcattgact
    26581 actatatcat tttctaaatc aaattcttct ttaaatgcta atacatactc tcctatctca
    26641 tgctcattaa atctaactct cttattatct aaatccctgt atattttacc tcttctatct
    26701 attacacctt tggtaatcat ttgacagatt aaatcaatta taccagaacc acatatacca
    26761 actggtgcac attcatcaat aatctttaat gttggctcta aagtatcttt atcaataatt
    26821 actttctcta ttgctcctgc tgatgctctc attccacagc ttatccctcc accttcaaaa
    26881 gcaggtcctg ctgaacatgc acagctcatc atataatctt tatttccaaa tacaatctct
    26941 ccattagttc ctaaatctat aaataaaaca ttttcttcac ttgaccatat ccctgctgat
    27001 aatacacctg ctgttatatc tcctcctaca taacttgcaa cagatggagc taagtacaca
    27061 tatgcactgt catttacaaa aagaccaaca ttttcaccca taagttttgg agattttaaa
    27121 aatggtggta tgtaaggttc ttgtcttaag aagtctgtat acacacccaa gaataaactt
    27181 gtcatagttg tattcccggc agccactaat gtaactacat cttccttatc tattccattt
    27241 ctttcatata ttgtttttaa tagtggattt atagtttcct caactatagc tttatgaagt
    27301 gtctctaatc catttttctt agttgaatat ataattctat ttataacatc tgctccatat
    27361 tttatctgtg catttccaga agatgcttta tctactacct cttttgagta taggtctact
    27421 aaacaaacaa ctactgaagt tgtaccaata tctattgcaa ctccgtataa ggaattttct
    27481 ttatttcctt gttctatatt tatgattgta agtttctttt gtttttgaac atatgttatt
    27541 gtaaccttaa aatcactctt tctaaataca gttggcattt ttctaagtat atccaatcta
    27601 aaatctattt cattatatcc taggttattt ctaacatatc tttccaatct atctacatca
    27661 cttatattat catctaaatt tggttcttcc atttctatgt atttcttttt tatatttgtt
    27721 ttaaattgaa ggttatgttc ttcaattatt tttttagctc tttcaaaaat ttccctatcc
    27781 tcttttttat tactaccttc tatcttcata ccatgcatag aggatgatac tttagaagga
    27841 acttcaattt ctatatctga tattaccttt gtacaacaag ctagtatata accttgctcc
    27901 cactcatcat ctgttatatg tcttgttttt tctgtatcaa cttttccatt caataatttt
    27961 actttacact tcccacaaga cacgtttcca ttacaaggag catctatgaa tatatctgca
    28021 tttcttgcaa cctctagtaa tatatccccc tcattacaat aaacctcttt attgtttggt
    28081 gtaaaactta cttttatcat gttatccctc ccaatttgtt ctatatatga taaaaggaaa
    28141 gtatagctaa atttgcgtgc actcaaattt tactatactt tccccaatta taataatatc
    28201 ttaatcttta attattctaa tccagcctcg tattctttat cacttaataa cgtatcaagt
    28261 tcagccacat cagctagttt tacttttaat atccagtttt catatgggtc ttcatttata
    28321 cattctggct catcttctaa tttttcatta acttccaata cctcaccatt aacaggagat
    28381 attaaatcag aagctacttt agaagactca actactccaa aatctactcc cttagttaca
    28441 gtatcttcta cttctggtgt ttcaacaaac aatatttctc ctaattgatc ttgagcatag
    28501 tctgttatac ctatatatac aacatctcca tcaattactt ttacccactc atgatcttta
    28561 gagtatttta attctggtaa taatttcatt tcgatagacc cccaatatta tattattgat
    28621 taaattactt aaatcatatt aatattatat catattattt taaattttcc atcaattaca
    28681 ttacactttc catagctaat gctggatgac ctttttcttc taagaaagct aatactcctt
    28741 cagaatcgtc agctatagtt tcatcacaaa ccatatcaca gaagttttct attccagtca
    28801 tttctttaac tgtagcattt aatttatcag ctacataatc ttttaattct tttggcatcc
    28861 aaactattct ttctggtcca ccttctgcat aagcgaattt tttagaagat atgaaatgtc
    28921 ttccgtgtcc cataaatcct ggagtttgaa ctcctccacc tgtcatagaa gcaagttctc
    28981 cgaaagtcat accaactgga gtaacacttg caaattctct gttaactaca acaaatccat
    29041 ttgcttctgg cattatacca cagatacatt cgaagcatcc acaagaagtc attgggtctt
    29101 ctagtataga atataatgta acagattcaa ctgcaccttg agatatttgg tttacagttt
    29161 catttactga attccataca cctgttctat catctaagca ctcgcctttt tctattggtt
    29221 gacaaggacc tgttgggtct agttctttag tagccttagc atctaaccag ctaactgctc
    29281 cacaaagacc aagtctttca ggagtaacaa cacaaacgtg agctggtgca aatgattgac
    29341 ataagttaca agaatagaaa gtatcaacac tttcatcaac taatgaagct aatctttcat
    29401 ctctagcatt gtacttagct attgcttctc cttttaattc agaaactttt tcagcatctg
    29461 taattatagt tatttcacac ttatcaacta ctgattcaaa ttcatctaac atcttagcat
    29521 ataaaacttc tcctatatgc tcaagtctaa atcctttatc aaatgcatct ttagagattc
    29581 ttacccaagc catatctctt tgtccaacgt gcattacacc ttctatatag tttaagaagt
    29641 agtggaaacg tctttcaaga actggctcga aatcttcttg catattttta ccagctattt
    29701 taactattac agcaagtggt aatcttaata caccatctgc atcaacttca tctatatttg
    29761 gtcctattat ttctatctta tggtcttcaa cttctgttgc ttctttctta acaacaagct
    29821 cccaagcttc agttctgttt ccaccaaact cagcaaacat atcgctcttt ctaattctct
    29881 caccttcaaa tgctgctgca aatgaaactg ggataggtat ttcagtaact tttattttta
    29941 ttcctctagc ttctaatgaa gtagctacta tcttatcgta atctttttga gttaataggt
    30001 tcattggaac ttcaagaact gtttggtcag ttataactgg gaatcctaaa gctattgctc
    30061 cagcacctgc agatacaact aattcactta atggtccaaa tgcattaaca aatgcaggaa
    30121 ctctattagc tgtgtactct aataatccgt ttaaatcacc aggagttaat ccaccgaata
    30181 ttaatgctgc tcttactgca acagatacaa cgtgtataac agaagttaca tcatatccta
    30241 gaggtataac tcttagctca agacccattt ttactccagc ttctatagct tggtctataa
    30301 ctttaccaac taagaaagtt agtaaacctt tagattggta atcttttata acttttgctg
    30361 ctgattctgc atctggacac tcaccaagaa caactgcaac accaggtata tctcctgtaa
    30421 ctaatggtac accaagtgat ctgattatag ggtcagttat atgacctgca catggctcac
    30481 tatatggagc atccatagtt gaatatttta atgcttcaat tacttctgct gctaaagctg
    30541 tagctaaacc agcattaaaa gcatgttcta gtaaatgagt tctatttatt aaagatttta
    30601 ctacttctaa agcaccttct aagtccccta aagtgttcat cttttgtcct gttgcagcat
    30661 atatacaagg taatgaatat gctgtatcag ggaaagcaac tttatgctct tttccattct
    30721 tttctatagc ttcagctaac atagcttgag ccgcacctaa agcttgttct gaccctgtaa
    30781 agattatatt atatagattc attctatttc cccctttaat atttacacct attttttatt
    30841 aactataccc taaaaaccct agaaagcaaa tccaccttca tttaactcta agaaagagtc
    30901 tgcatataaa gatgccccgt tgattatgtc acaagatttt acagttttca ttaattctgg
    30961 gtcacatgga ttcattatag ctgaactaaa tccattagcc attgccattg ctaagaatgc
    31021 actatctaaa acaggtctaa catgcttagg acatccatta gatacgttag ataatcctcc
    31081 tgtagttaaa agtcccatct cagtcatcat ttttatagct tctaaaactt ctacttgttt
    31141 ttcttgcata ccttttataa ctaagcataa tgggtcaaat agtatatcag ttggctccat
    31201 tcctaacatt aagccttttt ctaatatttc ttggcagtaa gccatacgct catcattatc
    31261 tcttgggata ccttcttttg cacataaacc tataaccatt gcttcgtatt cagctgctat
    31321 atctattaaa tcaaatcttg agccagcatc agcagagttt attattggtt ttgcattagt
    31381 tctatcataa actttaagtc cagcttcgat agctttttta ttagctgtat ctaatgctat
    31441 aggaacattg ttgaactcag attgaagtaa tttgattccc catgtcatta tttcttcgcc
    31501 atctctttcg gcaggtccta tattaaaatc tatatagtgt gctcctgctt ctaattgctc
    31561 ttttgctctt tttaagattg gagctgggtc tctttctgct aatgcttttc ttattgaagg
    31621 tgatatacaa tgtattctct cacctataat cataaatttt tccatttata atgtccccct
    31681 ttaaatttaa tattaatagt tagttaatat tttattagtt tgtttggcat gctttttctt
    31741 ggtatccttt taagaactta ggtaattcca tagattcctc tggtcctata actacattcc
    31801 atcctggtaa gttatcttct atatcacctt taagtactgc aacttttcct ggaatgataa
    31861 ggtctttaca attagttact tcttctacct tactttcttt aatgaaagca gagattgagt
    31921 ttccaccaaa tttaccagca gcccaagatg taagaactga atatccacct gcatctggta
    31981 ttactaacca tactggaact tttgatcttt ctatatcacc agcaactatg aagtaagtta
    32041 atgcaaagtc aacagtaact aatactggag aattttcatc tggattgttg attggataaa
    32101 tctttggttc aactctcatt ggtctttgtg ggtcagtgta tatgttttgt cttagtgcaa
    32161 ataatggtaa tgccttagca taactaatat catctattac tattatagaa ccgtatttta
    32221 tagtgaatat tgatgataaa gcaacttcca tcatagggtt tgaattagat aatctatttg
    32281 caaatactat tgaaggatat ccaaatgttc tatcttgctc ttttaaagct gttcttctaa
    32341 cttgtatagc attagtgtaa gtatctttta tgttttctcc tgttacatct aatactaatt
    32401 ctttatatcc agcagcttga attaattcaa ctgtttcata taattcttct aagctaccag
    32461 cttttacacc taatggtaaa cttgctcctt taactacttc tatcatatct ttgtagttct
    32521 ctttagttgc tccatatacc attggtctag catcttttaa tacttcaaca gcttctttaa
    32581 ctacttgtgc atcatcacaa gctaaaatat aagctacttc taatccactg ccttttattt
    32641 tatctattaa ttttaaatac gcatctttat ctccacaata ctctaaaaca gccatttcaa
    32701 ctttcatttg ttcaccaatt cttacatagt caactttttt catgttagct attttagcat
    32761 ctactgcttc atcactcata caagtacaga atgaaactgc atatctattt ctacttacta
    32821 atgttttttc atgtctaaat aatactgttt ctccacctag ttcatactca gatgcaccag
    32881 caccaacttt taaagctttc attaaaggtg cagtagcctc tgataatttt gctatagcgt
    32941 catcagacat atgtgggcat ttacctactt ctacagctcc tgaagcaacc ttcatagaga
    33001 aagccataca agttgggaat ccacaatcct tacagttttt ctttggtgtt aatttaaata
    33061 tatctaaagc ttttaatgcc attatttttt ccccctaacc ttaacaattt aattaagcta
    33121 atgcgttaac caattctttt atagtttcta ttgattttgg atgacgaagt ataactgcgt
    33181 ttgaaccacc tactaaaaca cttgctgcag ttgaaacttc cattgctata gttctttctt
    33241 ctggacaacc ccaatctggc tcatcttcta ttggagctat agcttcttta acatgaccta
    33301 cttcaaaagc tactggtgtt atgataggca tttgtaatgt cttatcattt tgaccaaatg
    33361 ctgcaagtct aattctatcc atagtagatg caacgtactc atatccataa ccaactgctg
    33421 aacatccaac attcataact atattttcac ctttaacgcc tagttgagtt aacaatacgt
    33481 ttaattgttt agctaggttt atatcaacag aagattcagc tcctacttta tgtgcataag
    33541 ccataccagc tgatgctcct actcctttgt agttatcttc tactgctgac ataaataagc
    33601 agttatgtcc atccaatgtt tgagctaatt tttcaaataa tttaccatct ttttcatgat
    33661 ttcctgaacc agctacaact aaaggtaatt ttattgcttc aattactgcc ttagctacat
    33721 cagcacattc atcaactgac ttatctaatc catttgggtc agaaccatca aattttaaac
    33781 aaataaaatc tgcttgtgta ttagcttcaa catatttagc ccactctact ggacaattag
    33841 ctacatcttt gtataattcc ttatatgagt cagtccagct ttcaggataa acgtctgata
    33901 tttgtatccc tatttttgga gaattaccta cttctccatc aaaactataa aaaggtaata
    33961 cattttcccc acctaattta attgcttttt cccctattcc tacttcaact tctgatattt
    34021 ttccagaata tttttgagta gacattttaa atgccatatt tttttccccc ttaagcctat
    34081 tttaattcta atttagcaaa aatttctttc atagccactt tagattttga atcttcaggt
    34141 aaattaacta aaggaatacc tgtagaatca tattcatata tcaattcatc cataggtaca
    34201 acaccgatta gctctaggtt atgcttttca atttcttctt taacaccatc attcataacc
    34261 ccatttggaa ctttatttac aatcaaaagt attcttccaa cacttaactt tagttcctca
    34321 gctaaatctc ttattctagc aacagcttgt atgctacgtc ttgagcaatc actaaccaat
    34381 aaaagtgtat caacatgtct agtgactttt ctacttagat gttccatacc agcttcgttg
    34441 tccatgacta agtatttgta atgaccagat attttgttta cttgttctct aagtatccca
    34501 tttacaaaac agtaacatcc ttcaccttct gacctaccca ttactaataa gtcatatcct
    34561 tcgccttctt cgattataga atttaatcta aattgaagat attgtgcctt tgtcatacca
    34621 ccagggaatg cattgcctaa cttttctctt tgatttactt cttctcttat ttctcctatt
    34681 gttgcttcaa cttcgatacc taacacttca tttatgttag cattggcatc agcatctaca
    34741 actaatactg gtcccttttt gtccttaacc aaataatcaa tcaaaagccc tgtgagactt
    34801 gttttaccag ttccaccttt tcctgcaaca gctatattgt atcccatttt aagacttccc
    34861 ccttaaatct agccacagag ccttatgtac tctgtctgtc tattataatt taggtacaga
    34921 atgaacacat tctccatgta catcatgaag tgcttccatt agcccttcag ataaacttgg
    34981 atgtggatgt attgcatccc ctacttgttc tactgttaat cctagatgaa cagcaagtga
    35041 caactctgtc aataaatctg tagcatgagg tcctactact gctgcaccta ttatcttatc
    35101 agtttctttg tcagctataa cttttacaaa tccttggaaa tgtcctatag cttgtgcttt
    35161 tccaagacct ctaaaatcaa attgacctac attgtattct acaccttcag cttcaagttg
    35221 cttctcagtc ttaccaacac cagcaacttc aggttcagta taaacacatc ttggaattgc
    35281 tctataatct actaccttag tcttacctaa agcattttca actgctacga taccttcttt
    35341 agaagcaaca tgtgctagga aaggagtatc tattatatcg cctattgcgt atataccttc
    35401 tacattagtt tcaagatgtt cattaactac tacttttcct ctttccattt caattcctat
    35461 atcttctact ccagaattgt caaggttagg tcttctacca acacatacta atgcatattg
    35521 tgcttctata acctttccat tagaaagagt tgcaacagcc ttaccatcaa ctacttcaca
    35581 agtttgtact ccaatacctg taataacctt aattttatct ttcttaaatt gtctaagtag
    35641 ttgtttagct acatctttgt cttcatttaa tagtatttgg tcaaccatct caactatagt
    35701 tacttctgtt cctaaggctc taaagaactg ccctatctca catcctataa ctccaccacc
    35761 tactattaac atagactcag gtatctcttc aagtccaaga acttcatcac tagttattac
    35821 aacttttcca tcatatggga acattcttgg tacaactgga acagaaccat ttgctagtat
    35881 tatcttatct gcttttatag tttctactgt tccatcatct ttagttactt ctatagtgtt
    35941 tttatcaatt aattttccaa aaccattaac taagtttact cctctttttt caaataagaa
    36001 ctctatacca cttattaatt ggtttacaac tttatttttt ctttccatta tggcagtgaa
    36061 gtttggctta actgtaccat ctatttctat accaaaatcc tttgcttctt ttacagtatt
    36121 caatactcct gaagaagcaa gaagtgcttt agttggtata catcctgcat ttaagcaagt
    36181 tcctccaact cttctttttt caacaactgt tacatctgca ccaagcatag aagcttttat
    36241 agctgctaca tatcctcctg gtccaccacc tactactact atcttcatct ttaattcccc
    36301 caaacctaat ataatctaca atcttgcaat actataaacc tgcggcatcc agtatagcag
    36361 gtatattctc ttctgcccca attgccatta tatgaacacc atcacataaa tcttcttctt
    36421 ttaattgttt gataagttcc cctgccattt ttattccttc acttacccag ttttcttttc
    36481 cagctgctct taatctttcg atttgttcat ctggaacaaa tattcctggt acatttgcag
    36541 tcataaattt agccattcct ggtgatttta aaggtactat tcctgctaat accttgcaat
    36601 ccatatccct tgttaattct ctaaactttc tcattgtatt tatgtcataa agtgcttgtg
    36661 tttggaaaaa tttagcccct gcttttattt tctttttcat ttttaataat tgaacttcta
    36721 ttggagaata ttctggagtt actgatgctc ctagataaaa atctggagaa ccttttaact
    36781 tattaccagc catgtccgta cctgccatta aagtctcagc agtttgaagt atccccacag
    36841 aatctaaatc aaacactccc ttagcttgtg gatggtctcc tacgctagta tggtctcctg
    36901 ttagtgccaa cagattgttt atcccaaata cacctgctga caacatttct ccttgtatag
    36961 ctattctatt tctatctctc cctgttattt gaataactgg ctctaatcca gcatctttta
    37021 ataatttaca tgtagcaaga gaagttgctc tcataactgc cgattgaaag tctgttacat
    37081 ttgctgcatg aactcttcca actaacggct ttgcacattc tattaaatgt gaaaggtcag
    37141 tcccttttgg aggagccatt tcagtagtaa ctgcaaattt tccactttct aatgtttctc
    37201 ttaataagct catctctaat ccccctttta accttctaaa aaaaactttt atgaatttgc
    37261 tgctgcttct ttctttttct ttgcacttaa acttcttgga ttattttgct tagaatagtc
    37321 ttttggtggt cttatttctg ctaagttatc taattgtcct atagcttcta gtctttcata
    37381 tatctttatc caagcacaat cattctctga gtttacttca cacttaccat ttttagctcc
    37441 accacaagcc ccattcataa gacctttagc acacatagtt actggacata tcccacctgt
    37501 ccaaccaagt tcacagtctc cacaagcctt acaggcttct tcatattctc caactctttg
    37561 tacttcccct ataaacaaag tattgttggc tggataaact ggcttatctt ttaaattctt
    37621 aactattgtc tgtgtaccat ctccacatgc taaagataaa actgcatcag cttccttagt
    37681 ctcttctttt agagccttta aatccttttt agactttaaa aggttacaag cagggtcaag
    37741 cattacatat cctaagattt ttttgccttc accttcaaga gtttccttca tttttaaaac
    37801 ttcttcttcc ccaccacttt tacaagttgc tgcacattga ttacaaccaa ctaaaaccag
    37861 cttgtcaaaa tcttttaagt accctagcac ttcttctaat ggtttatttt cagaaattat
    37921 catatctact tcccccctaa accttccaca tatatatatc tatttattgt tttgtaattt
    37981 acaagcctta actacatgtt ttgcaagtat agatgttgta actgaaccaa cccccgctgg
    38041 aactggagtt atcattgata ctttgtctaa aactgcattt gtatcaacat ctccacataa
    38101 atttccttct tcatcaacat ttataccaac gtctataact accgctccat ctttaacaaa
    38161 actttcatca accatcttag ctctaccaat agctgctatt agcacgtctg cctctgctgc
    38221 tacacctgat agatttttag tttttgaatg acatattgta acagttgcat gttcacttaa
    38281 taaaagcatt gatactggct ttccaactac cattgatctt ccaagaactg ttaccttact
    38341 tccttttaaa tcaacattat agtgttttaa tatctcaact actgctgtag gtgtacatgg
    38401 tggaaatcca cttttatccc cttccattac cttagcagag tttattggac taaaacaatc
    38461 tacgtctttt tccggtgcaa taacatattt tataacttct tcatttaagt gttttggaag
    38521 aggtctaaaa cataatatac cattaacatt tttgtcatca ttaactctct ttaatacatc
    38581 aatatattcc tcttgtgtta tatcctcagc taactctaac acttctgttg ttatacctat
    38641 gttttgacat ctctttagtg ctcctctttc ataagataaa tcatcacttc ttgccccaac
    38701 tctaactatt gttagtttag gatttatacc ttctttaatt agtaaatcga cttcttttat
    38761 taattcttca ctaattttat cagctacagg ttttcctttt ataatttgtc ctttagttga
    38821 cattccttcc atacattcac aactccccta caagcaaact taaattaatt tattctatat
    38881 accacatatt aataacatag tatctacttt cgtcatttaa aaattatttt ccaagagctt
    38941 tttcaacttt ggcataaact tcatcacaaa tttttacacc atcttcaact aacttatcta
    39001 cttctgtttt taccttatta acatattctt tatcttgtat agaatttata tttataacta
    39061 catttaattg tccaccaagt atagcagctc ttaaacactg aactcctaca ccaacatcac
    39121 ttatagcaag tcttgaacct ttatcaacta aatcttcatg taacttaata gcttcatagc
    39181 aaactcttac tatgtttaat ggtacttcac aagcaacttt taatgccttt tccattgttt
    39241 ctgcttttat tcttttttct tcttctgttt ctttaggaag cccgtaagct tttgataatg
    39301 gtaagaaaca ttctgcatca tcatctatca tttttaataa atctttttct aactttcctg
    39361 ccttacttaa tatctctttt acactttctt catactcagc atacttcttc ttccctattg
    39421 taaggttaca taccatacta cctaaagcca tacctattgc acctactagt gcagcagctc
    39481 ccccaccacc tggtactgct tctttggaag atagtacttc tacaaaatca acacaagttt
    39541 tatctgctat tttcatgata atcctccttg aaaggatgta ggaaaatatc tcaaattgtt
    39601 cgagatattt tacgaactat tttaagatat ctcctactct ttatttataa attaatttcc
    39661 ttagaataat ccagctatta ctccattttc atcaacatct attttttctg ctgctggaac
    39721 ttttggtaat cctggcatct tcattatttc tccagtaagt gcaactataa atccagctcc
    39781 tgctgaaatt gttgcttgtc ttacagttat tctaaatcct gttggtctac ctaatttagt
    39841 ttggtcatca gttaaagaat attgagtctt agccatacat actggaactt tagtaaatcc
    39901 aagtttttct aagttagcta tttccttatc agcttcagga gtataatcta caccatctgc
    39961 tccataaatc ttagtagcta tagcatttat cttgtctttt atagataaat catcttcata
    40021 gcagaatcta aagttatttt cttcttcatc caataatctt aaaacttctt tagctactgc
    40081 aattccacct tctccacctt ttgcccatac ttcagaaaga gcaacattaa cacctaattc
    40141 cttacacttg tcttcaacaa gtttaagttc agcttcagta tcaagtggga atctgttgat
    40201 tgcaacaact gctggtaatc catatacttg agttatgttt tcaacatgtt ttaataagtt
    40261 tggaagtcct ttttcaagag cttctaggtt ttcgttattt aagtctgctt tagcaactcc
    40321 accattgtat tttaatgctc ttacagtagc aactattata acagcatctg gttttaagtt
    40381 tgccattcta cattttatat ctaagaattt ttctgctcca aggtcagcac cgaaaccagc
    40441 ctcagttatt acataatctg caaagtgcat agccattctt gtagctataa cagagttaca
    40501 tccatgagct atatttgcga atggtccacc gtgtacaaat gatggtgttc cttcaagagt
    40561 ttgaactagg tttggtttta aagcatcttt taataatgca gccatagcac cattagcttt
    40621 taattgtcta gctgttacag gttcaccttc gtagctgtat ccaactatta tgtttcctaa
    40681 tctttctttt aaatcagata tatcacttgc caaacagaac gctgccatta tttcagaagc
    40741 aacagttata tcgaatccat cttgtctaac tgctccatca ccttttttac ccataccatc
    40801 aacgatattt ctaagttgtc tatcgttcat gtctacacat cttctccaag ttattttctt
    40861 agggtctatt ctaagtgcat ttccttggtg aatatggtta tcaagcatag cagctaaaag
    40921 attgttagca gctcctatag cgtgaaaatc tcctgtgaag tgtaagttta tatcttccat
    40981 aggaacaact tgtgcatatc ctccaccagc tgctccacct ttaacaccaa atactggtcc
    41041 tagagatggt tctcttaaag caactaatac atttttgtct agtttagcaa atgcatcagc
    41101 aacacctata gtagtagtag tttttccttc acctgctgga gttgggttta tagctgtagt
    41161 tagtattaac ttagcttttt taccagtctc tctttttagt agattgtagt caacttttgc
    41221 tttgtattta ccataaagtt ctacatcatc ttcacctagt cctaattttt ttgcaacctc
    41281 tctaatatct tgaggcttag cttcttgagc tatttcaatg tcagatttaa atcccataac
    41341 tgaatctcct cccacaacct aaatagattt aaaatataat ttttgtaaaa attgtattaa
    41401 tatgtaaaaa ttatatttta taagataatt atacatgtaa aattacttaa aaactagcta
    41461 ctaagctatt aaaatattca aacttaatag ctagttattt atctaattac ttacttatta
    41521 cctatctatt gcctatgtct aacctttaac caacttaaaa tcccaaatca aaatttctat
    41581 ctattttatt tattcttaag tgacattaat ttatctttta ttgctttaat ctgttctttc
    41641 gttgtttcac tagaatcata tggagattga ttagctctat cagaatcaat aacatcttgg
    41701 ttataataaa taaatcctaa agattctcca tcttctaagt tttggattat aaattcttca
    41761 tcttccttat ttctaatttt atttcctact acaaatactt tatttacacc tatatcatgt
    41821 ccaagtttct taacttttct ataagtctgt aaacttctct ctcctggttc tacaactact
    41881 ataaaagcat ctacaccttg ggctgttcct cttcctaagt gttcaattcc cgcttccata
    41941 tccataacca ctacatcttt attttgtagt attaaatgtg agcagagtct cttcaaaaga
    42001 acatgctctg gacatacaca tccagtacca ccagaatcta cggttcccaa tgtaagtaat
    42061 cttactccat tgtattcttt acagaaattt tcagggatat cgtctacttt aggattcatc
    42121 ttaaacattt ttccaaatga acctacagaa gcagctgttc tatctgaaac taattttttc
    42181 atttctgata taggtactat tgattcatat acttcttttg gaaaacctag tgctaaagct
    42241 aaattagcat cagggtcggc atcaacagca acaactctgt atccgtcttc agcaaacatc
    42301 ctagagagca ttgaagaaaa agtcgtttta cctactccac ctttacctgt tattgctatc
    42361 ttcataatcc ctaccacctt ttattactat ttgcttttta gtagttaatt ttacagttaa
    42421 atatttttta tactctatat ttttatacac taaaaataaa ctacagctag tccttacagg
    42481 aaccaattaa atttacccta ctagcttttc aaagcagcat gtatagtttt attattcttt
    42541 aatattgttt aatattgttt atattttatt tattcagtat attcattata ttttgatgtt
    42601 ctttacttta atatttgact ttattcaact ttattcaacc agaaacttct tataaaaacg
    42661 tttattctat aacttcacta ttttttaagc ttcagccttt tctgccattt tttcttcaac
    42721 taatgcttca aagtgaacac gttttttctc tatatcttct attattgtag ctgctaactc
    42781 ttttggattt gtatttacag taaatgtagc tccaacttta tcttttaatt cactagttaa
    42841 tatatccact gctcttgaag aaccagctat tggaggcatt attcctaaat aagtgtctat
    42901 accagaagct acaacatagc atcctatagc aactgctttt tctgacatcc actctggagc
    42961 tatacctaca actggaaggt cacacatatc catatctaag taattagctg ctgctccaac
    43021 taaatctagt atacggctta tatcaacaca agaacccata tgtagtactg gtgggattcc
    43081 tactaattta cagacagttg caagaccttt acctgcatat ttttcagccg catcagattc
    43141 cattaaacca aacttagctg ctgctgaagc tccacaacct gtagtaacta ctattatgtc
    43201 gtttttgatt aattctttca ttattgttac gtgagcctca tttgaaactc ctttagcatt
    43261 gttacatcca actacaccag ctgctcctct taatactcca gattttagac agtctgttaa
    43321 tggcttaact gttcctgctg ggtctatatg agagtttaca actctgtcta attgatttac
    43381 tactgcttct acactatacc caactgttgc gcctgatttt aattcaggta taagtacttt
    43441 tgatttatct ctatttttaa agtttaaaat agcttcttta actattgctt tagcatcatc
    43501 aagtgcttgt tcttctctaa attcaatata agttgaacct gttatcttag cttttggaga
    43561 agttgttaca aatttagtat ggtaacaatc tgcaactcta gctaatgcag ggaatataca
    43621 ttgaacatca actattacag cttcaactgc tccagttatt attgcaagtt cttgttgatg
    43681 gaagtctcct gctattttta caccatgtct cattgtaatc tcattacctg tacaacacat
    43741 acctgctaag tttattccat cagcaccaac ttctttagct aaagctacta agtctggctc
    43801 ttctgatgct aaaactatca tttctgataa tgctggctca tgtccatgta atattatgtt
    43861 aactttattt tcttctaata ctgctaaatt cgcctctgtt cttcttggca ctggagttcc
    43921 aaataagata tcgcttagac gagtacctat catagaacca ccccaaccat cagccataga
    43981 agttctaaga ctcatgtgta ttaaactatc tatatcacca gtacatccta tatgagtaga
    44041 gtgcattatt gttgcaattt ctctatctat agctcttggc tctatagcgt attctttcca
    44101 tattttttgt cttggttctg gtgcattttt tataaatctt aatgtcccaa aaggttttcc
    44161 aaattccatt aatgcaattt ctgccacttc atgtgctaca tcatagatat ctctaccttc
    44221 tgtctctaca tcccattctt tagctaaagt aattaactta gcttcgtctc ttattttata
    44281 gtttccattt ggatcagcta atgctaatgt atgtgctata tctctagcat ggtctgaatg
    44341 ggcagctgtc ccaccagcaa ccattcttgc aaagtttcta cctactatag tatgctcatc
    44401 tgctccacat aacccccttg gagtcttagg gcttattcta catggtccca ttccacatat
    44461 tctacagcaa acaccttgaa gaccaaaacc acattgtgcc ttaaagcctt cttttctatc
    44521 atacattgtt tctacgcctt cttctctagc tttagctatc atcttctggc tgtttaaatc
    44581 aattgttaac attttttcat ccatattcct atcccctttt tttgattttt aaaatccccc
    44641 aggtgactga cttcatgtca taaaataata aaataaatgc tttctaagtt gattatatac
    44701 taattttcag tgctttgctt tagatttaaa tattttttta acaaaattag ataatacata
    44761 aaaattttat tttctacact taatttaagt tgattttatc gcttgttttt ggctatttgt
    44821 taatatctaa acctactttt ttgatacttc agtttaatta aattatgttt tgattttttt
    44881 aaatcaaatt tgaaattttt ctagtcattt ttatattatt gcagattgtt tgtgtattta
    44941 ttatctttca ctactgtttg gacttattac agatttttac tccctaaact taattagtaa
    45001 aaacttctta gaatagcatt ttttggacta atttttttga atttttttat ttttcctact
    45061 ttaatattaa ttatagcttc aaattgaaca tttgtatata ttcatttgaa gctataatta
    45121 ttttttatat aaaacttttt taatacagca ttaatttaga cattttgact attttttcta
    45181 ctttaattca tttatttcaa gcgatttatc ctatttcata tttttagcta caatagcccc
    45241 atatgcaata gaatataatt tagattcatg tgaatcagct cttgacacta aaactatagg
    45301 agcttttgca cccataatta tacctgctga tttagagtct gccatatatg taaaggcttt
    45361 ccctattcca ttaccaacct ctattgttgg aaccaatatg atatctacat ctccagatac
    45421 ttcactttta aaccctttta tctcactagc ttcttttgaa acagctaaat caaaagccag
    45481 aggaccttct acaattacat tttcaccaaa ttctccttct ttacaagctt ttgctaacat
    45541 atctgcatct acagttgctt gcatcttagg atttactttc tctttagctg ccaaacatgc
    45601 aacttttaca gtttccattc ctaaagcttt tgcagctttt atagaatttt ttaatatctt
    45661 tgccttttgt tcataatcag gagctatatt catacctcca tctgtagtta taagtaattt
    45721 atggtatttt tctaactcat ataccataac atgacttaat aaactatcag ttctaagacc
    45781 atagtcttta tttaacactt cttttaatat gacagatgta tctaataatc ctttcattac
    45841 aaagtcagct tctttacttg atactaattt aactgctatt tctgcacact ctttgatatc
    45901 atccttatcc actattttga taccacttaa atcaaatcct atttcttttg atatttctct
    45961 tattttgcct tcatttccaa ccaatatagg agtaattata tttctttcta cagcatcctt
    46021 tattgccatt aaaacttctt tatcatgagc tgctgctaca gagagtacaa ttttctctcc
    46081 tcccttaagt tgttctaaaa tatcatctaa tttttttatc aaaagtaacc cctcccttat
    46141 atatatttaa ctaaataata ccatatttgc tatacctttt ctcaatttat tttttatgtt
    46201 ataaagaatt tatataacta aaagacagtt taatatttta ttctgggatt tcatcaatag
    46261 ctcttaaaag ctttgcagga acaccaccta caatagtatt ttctgcaaca ttttttgtta
    46321 caactgctcc agcagcgata attgcattat ctccaatagt aactcctgga actcttcata
    46381 caaaaaagag gcttatctct attttgagat agccccactt aaccaataaa attaaataca
    46441 acttaacaat atccttactt atttattcca agttctctta gacaagcaat agtaatttca
    46501 tcttgtggat ttaattcata agctctttct atatagtaag ttgcatcatc aatatcacca
    46561 ttatttaaat aagccattcc taaattgcaa agtatttctg ggtcttcctt tatcttagcc
    46621 gcttgttcaa aatactctat tgctttatct aaattattct tataagcctc acaaagcccc
    46681 aattccacta tagtatccac ttgattaggc tttattatca atatcttctt aagatacatc
    46741 ttagcctgct ctatttcgcc cataccctta tatccaagtg ctatcataaa cagcaagttc
    46801 caccaatcca tatgttcttc ttctaatgga agtaacttct ctaatccttc cttaaactta
    46861 ccttggaata caagcgtata tccttcttca tattgaactt taaagtccat cttgcccaga
    46921 ttctcttgta cctcagctac taaatcagca tctaacccta gccttaacgc ttcttcccaa
    46981 gtcagcttag tctttaaata ttgaccttga ttataataat ggtagcctaa gtgataataa
    47041 cctaatgcaa aattctcatc aacatcaatt accttttcaa gcttagccat ggcttcaagt
    47101 aagaatgcat tcattgcctt atcatccata tctttttgat actgtttagc tatctcttgg
    47161 caaacaatcg catagttata cattgcatct aaatcatctg gatacattgt tataaatgct
    47221 tttatatata ttaaagaatc tgtatgttca ccaatctcaa agtattttct cgacatatat
    47281 cccatatacg atttcaaatc caaatcaata tcttttgata aagcatttaa aaacttctca
    47341 tactctgcat tgtttttaaa cttactatct attccaatta tatatatcat tgcatctgct
    47401 atagacattg aatttaactt atcttgagca gtcttttctt ttatcccttt tactaatacc
    47461 tcatttttta taggtacatc taatccacct tttggcactt catagctttt taatttaaac
    47521 tctccaccat gttttatagt tataaaagct aattcttctg ctttttttag caaatatttt
    47581 tctatcttaa aatccatttt atcctcctaa atacttaaat ctctacttta tgagttttag
    47641 atttctcaaa tattttttta tcatcatact caaataagac tacattttct acttctctta
    47701 tttctgtatt tatatcattt tttaaatcca caacattaaa tctaaatggc tcaaaatgaa
    47761 catattttat tatatgttta gctggtttat caacaaaact aggtaaatat gttgataagt
    47821 tatcattatc ttgtaaaaat acatggcatc tattcttaaa atcatccaca tctagcttat
    47881 taaaaaactg tggtatattt gatgttttac ccagtgatat atagtcatat tttaatatat
    47941 cattgaatac atcattatct atgttgattt tttcattata gaaatccatc aatattttat
    48001 ataactgatt ctttccttgt gccaaatcaa agtagccatt ttcatcaaaa tacttggcaa
    48061 aaacctcaaa gaatttaaaa gggctttgtt tataaaatct gcctataata tatctcatag
    48121 ataacacaaa gtttttagaa ttgtagtatc tctccagtat attttctata tcctttagct
    48181 tcaaagtttc ttcatagctt atataattat tgtataaaaa ctcatatgga gcataatcct
    48241 tatatttaaa accatgctca tctgcaactt ttctcatacc tgtcccttta atcatcttta
    48301 aaaagcctaa ttgcagatgc tctataccta gattaaatac atcattaaaa gaattttcaa
    48361 agctcttata atcttcataa ggcagtcctg caattaagtc taagtgctga tgtatatttc
    48421 tataagatgc tacagtttgt acaacatgag acaacttttt aaaatcatcc cttctgccta
    48481 ctgcatcaag tgttttttca ttcgttgact gaacccctat ttcaaattga aaaagacctt
    48541 ctttacaatc agccaaaaac tcaagcatct tatcatctat caaatacgct gtaacttcaa
    48601 aatgataagt tgtatatcca ttatcatttt tcataagaaa atccatgatt tccatagcca
    48661 cttttctatt tgcattgaat gtcctatcta taaactttat ttgtgatact cttgcatcta
    48721 ttaaagcttt taaatcactc tttatcctgt ctaaactaaa ataccttaga cctggaatag
    48781 tagatgataa acagtattgg cagttaaaag ggcaacctct tgatgattca taatacacta
    48841 ttctattttc atattctttt ggattcaagt tttcataagg actaggaatc tcatccaaat
    48901 cttgaagtaa ttccataggc ttattcacta ttatctcatt gccttgtcta tatacaagtc
    48961 catttacatc atttatttcc atctttcctt gcaagtgaag tactaagtct ctaaaaatta
    49021 attctccctc tccataaagt atataatcca caaaatcata ctttttcatt gcctcataac
    49081 tatcataact cacttccggt ccgcccaaag ctattttagt attaggtcta atttttttta
    49141 gattatcaca aagtttaact atatctccca cattccagat atatgttgag aataatatta
    49201 tatcatattc atttttatat atatccttta aaatatagtc caaatcgtta tttatcgtgt
    49261 attctttcat attaacttct atcaaatctc ttacaaattc ttttagatat cttatagcca
    49321 aatttgtatg aataaacttg gaatttaatg ttgttaataa aattttcaaa tatttctcac
    49381 ctctttttaa gattatactg tctttttgta ccccttatag gttaaaatag tatatgtaaa
    49441 gtctaaataa tatctatata attaatttat taatttcaag taatgtgagg aaaggaagtt
    49501 ttttatggaa ttaattgaaa aagtatctat caactcttta tcaaaaagag atttactact
    49561 tattataaag tctcttgaat acactaatga aaatactcaa attagtgatt tcattgacct
    49621 taggaataat atagtaaagg aattatgttt tttaactgac actaaggaaa aagatttttt
    49681 agattatcta gaaaaaaata gcacactcta ataacctaaa cctttttaaa ctttaatata
    49741 taaatacctg atttagaatt tatttttatg cttaatatat tatcattaaa ggttttcgac
    49801 ataactgtta tttgattaaa tatagggtct actatagtat taccttcttc aagtcttata
    49861 agacttcttg ggtctatgct tttattatat gccttaactc caattttata ttttctcaat
    49921 ttaacaacat attcggacat agaaaaaata aaatctatat tatcttcatt taatttacta
    49981 tcttcaccca aaatggataa tatagatttt tttatgctat taattccttc attttctaca
    50041 gttctatctt ccatatatac atcatataga acatttaaaa catttaataa aatactttct
    50101 tcatcataat cttcagattt caaatcaatg tacttatcaa ttaattgtat tgctttaatc
    50161 cttgccatct gaaactttac aacatctgat ttgtctaatt ctatagaaaa tcctattatc
    50221 ttgtctttaa tactctgtag taattcgaca tactctattt tactattatt tataagattg
    50281 tgcataatgg aattatacac cacagaacct aataaataat caaataaaag ttcttctttt
    50341 ttaaaataaa taacatactt ttttattagt ttaataacct catcttcact tttttgaata
    50401 ttagtatttg ataaaattag tggtaataaa atatttaaaa aattgatatt tcctattttt
    50461 tctccataaa atctatagta aataagttca tctctcagtc tattttcgtc tatatacaca
    50521 catctttgcg ttttatcatc tattaaggat tttgtattta ttatagttaa atctttaaga
    50581 gccctacttg cactactaaa agaagatgtg tagacttttt ttagtaattc gtcattcata
    50641 aatatatcct ttctgaaaaa ttgaatgtaa ataaattgtt attaaaaaaa aagagacagc
    50701 ccgtttaaga agctgtcata tataggggga tagtagtgta caaaaatcat tgtaatctac
    50761 tatctatata ttattatacg atactacttt tttatatgta aagcatcagt tttcgacatc
    50821 cctatatttt acagttatac aaattgcgta ctaagttcaa ttttattctt tttatttcaa
    50881 cattttatca tgctacattc tttcaggagc gtgcattccc aacaatttca gagaattttc
    50941 taaagtttgt tttgttgcta aaactaatgc aagtcttgct tttcttattt ccaaattttc
    51001 tactaaaatt ggattgtcat gataaaattt attaaacgct tgagctaaat ctagcataaa
    51061 tctagtcact atatgtggct catttttctt tagagcaagt aaaatattct tattgaatga
    51121 ttctataact ctaagaactt ctgcactatc ttcatcagct aatagactat aatctatatc
    51181 agaagtcact tctacttctg cttttcttaa aactgcacag catctagcat gtgtatactg
    51241 aacatatggt ccagtctcac catcaaaact aagcgttctt tcccaagaga aggtatagtc
    51301 tttaattcta ctattagata actcttggaa tactactgcc ccaacaccta cttgcttaga
    51361 tatttcatcc acatttttag catttgggtt tttagctagt ataatttcct tagttttatc
    51421 tatagcttga tttaaagcat cttctaaaaa tactactctt ccttttctag tcgacatagt
    51481 accttcttca agtgcaacca taccaaatcc aacatgaatt aaatcttttg cccaatcata
    51541 tcccataagc tcaattacct taaaccattg ttggaaatgt aagttttgtt gagaaccaac
    51601 tacatatata cacttgtcaa aatcataagt ttcttttcta tatattgcag cagctaaatc
    51661 tcttgtcata tataacgttg aaccatcatt cttagtaata agtgctggtg gcattttata
    51721 ctcttctaaa tcaacaattc ttgctccttt agactctttt aaaagatttt tctcttctaa
    51781 tagttcgata accctgttca ttttatcaga ataaaaactc tctcctgcta aagaatcaaa
    51841 ttctatatct aaaagtttat aaactctgtt aaactctttt aaactctcat ttctaaacca
    51901 ttgccataat tcttgtgctt cttcgtcacc attttctaat ttattaaacc atgctcttgc
    51961 ttcatcttcc atttctgggt gttgttcagc ttcatcatgg aatcttacgt ataattttag
    52021 caattctgga attggattag actctactac ttctttttct ccccactttt taaaggccac
    52081 tattaactta ccaaactgag ttccatagtc acctaaatga tttattctta tagtcttgta
    52141 tccttgcgaa tcatatatct tatataaagc attacctata actgtagttc ttatgtgccc
    52201 tatatggaaa ggttttgcta tatttggaga agaatattca actattacag ttttatcttt
    52261 tccaaaatca ctatgtccgt aattttcttt ttcatctaaa acttttttaa ttacagtttc
    52321 tgctaattga gatttattta caaagaaatt tacatatccg cctaattgta ttacttttgt
    52381 tatctctcca cttggttcta tactttccgc caattcactt gctatcatgt ttggagcttt
    52441 tctaaatact ttggctaatt taaagcatgg aaaagcatag tcccccatat ccttatttgg
    52501 tggaacttct ataagtgcct ctatctcttc tttcgataaa tcttctattt tttctttaag
    52561 gcaatttgat attgccacct taaaatcttg cattctgttg ctcctctcta cattgttcct
    52621 ggtttatatt gtgcttatct ctttatgtta aatcaaattt cgtgtttttt caagtatttc
    52681 attacagtgt aaaacacttt aataattatg ttttctgtat atattaaaaa tactataatt
    52741 gcagttttta atcacactat tattgatttt ttataagact tttttctatt ttattgtttc
    52801 ttgtactatc cagttgactt tatatacttt ttttaatctt ttatctattt tcatacatca
    52861 atgtcagctt tatatacttt ttttactctt ttatctattt tctataaatc tttttcactc
    52921 ttaactttta ttccttcttc ttctaatagc cttgctgtta tacctttccc tggtatcttt
    52981 ttacctgaaa aactaccatc atatattaga ttacatccac aagaggggct accctctttt
    53041 agtattgctt cgctacatac atataaattt gctattttta gagtttcatt agcccctctt
    53101 acaaagtttt ctgttacatc cttattatct ttagtaatta cttttccatc aactatctca
    53161 gcaggtggtc ttggtgtaga tagaccacct aactgctctg ggcatacaag tgtaaattct
    53221 ttgcctttta aatattcctt gactttttca ttatcattat tatcgccact atatttacaa
    53281 tttattccta ttaaacatgc agataccaat atcataaaaa tgtgctccta tacaaattct
    53341 taatatattc tcatacaaat tactaatgta ttcttataca aattatttta atttaacaat
    53401 tgttactcct gctccacctt ctccatattg accacctctt tgtgatttta catgtctatt
    53461 tcttcttaaa atgtcttgta gccctgcttt taatactcct gtacctattc catgtattac
    53521 tgttacagac tctaaacctg ccacatatgc atcatcaaga tacttttcta cttccattat
    53581 agcttcttct aggtttaacc ctctaaggtc aacttcattt tttacactac cagattttga
    53641 ccttataatg tttctcgttg atttagttac atttgttgaa acatctttgc gtgttttttg
    53701 taaagattta aaaggtagag tcatcttcat tataccaatt tgcactactg cttcttttct
    53761 ctttttatct actgaaacta cactaccatt ttgatttaaa gttattacct taacttcttc
    53821 acctggcttt aagtctttta tctccttatt tgataccttt ggaactatca tactttttac
    53881 tgttggctga agacttccca tagagctagt caattctttt ctaagttctt ctatcttacg
    53941 attcttttct tttgaagctc tttcttgttc aagacttcta agttctttta ttataatatc
    54001 tacttcttct ttagcttgtc ttataattga aaatgcttct gatttagctt tttcaatcat
    54061 cttatctctt tgactgacca atttttcaag tttttcgtca tactctactt tcagtttttc
    54121 aatctcttct tttaatcttt cagcttcttc tctatcttct actgctttga ttctattctt
    54181 ttcaacattc tgtaacacat cttctaaagc tatgttttct gtatttatat attctttagc
    54241 acgtgaaatc acataatcac ttagcccaag ttttctagaa atctcaaacg catttgattt
    54301 tccgggaaca cctataagta acttatatgt tgggcttaaa gtttctatat caaattcaac
    54361 tgctgcattt tctacacctg atttagtaag agcataattt ttaagctcac tatagtgagt
    54421 ggtagctata catttagctc ctacagaatt tatatcttct aatactgcta ttgcaagggc
    54481 agctccttca acagggtctg ttcccgctcc taactcgtca aatataacta aagagtctgc
    54541 tgttacgttt tgtaatatag atactatatt cgtcatatga gatgaaaatg ttgatagact
    54601 ctgttcaata ctctgctcat ctcctatatc tgcaaataca ttatcatata cacacatact
    54661 acttccataa tcagcaggta tatgaagtcc actttgtgtc ataagtgcaa atagacctac
    54721 agtttttatt gtaacagtct taccacctgt gtttggacct gttatcacca atgtatggaa
    54781 gtctcttcct aaataaatgg tatttgctac taccttcttt ttatccagca gtggatgtct
    54841 tccatttttt atgtttaaat atttatcctc atttaaagtt ggttctattc ctctcatctg
    54901 tatagaaagt tttccctttg aaaatgcaaa gtccaatctt ccaagtatct cttgattaga
    54961 gattaaatct tcgctcactt ctccaaccat agcagaaagc tctgataaaa ttctttctat
    55021 ttcttcttgc tcacctagtt ttaactgtct caattcattg ttcatctcta ctatagtcat
    55081 tggctctata aaaagtgtcg caccagaaga tgactggtca tgcactatac cagctacttg
    55141 cgacctatat tcagatttta caggtactac aaatctatca cctcttagag aaattattgc
    55201 atcttgtaag tacttttgat aagtagttga acttattatt gaatttaatt ttgacctaat
    55261 ggattgattt ttttgggcta ttcttcttct gatatctcta agtgtacttg aagcattgtc
    55321 agatatttct acttcactaa ttatagcatt gtatatctgg tcttctatgt ccttgtatac
    55381 atatagagaa tttgatagag attgtattat tggataatta aaatcttctt catcactact
    55441 agataagcta tttcttaatc ttctagccac tcttaaggta tctgctatca taatcagact
    55501 tcctgggtca agagaagcac ctatataagc tctctttacc ttatcttcta tatcatgaat
    55561 accttccaac cctactgaac ctctctttat aataattgat tgagcttcac tagtttcttc
    55621 tagcatagat ttcacttcta caaaatcagt atttggtact aaattttcta tatactttag
    55681 acctaaagaa gatgaggctt tcttctttaa caaatctatt attttattgt attctagaac
    55741 tcttaacgat ttctcattca ttttctatat tcaccatcct cgatatttta acttttttat
    55801 ttaattttaa aaatgtatgt tttcaagcat ttccaataaa aactgcaagt tttatttctt
    55861 tttcatttct aaaattatta tattttttct cttttagata tattttacac atattttgta
    55921 ttatactatg tatgtagcta tctatatatt atacataaac atgctttatt tgtaatataa
    55981 tctgttaaaa aatcttcttt aatattttta aaggagttta ttttagctta taaaaaaaaa
    56041 tagctactta tatagataaa ttaaggagga acatgagtca tgggaaacgt attagaagga
    56101 ttaaaaccag aaagtgtttt taaaaacttt gagaaaatat ctcaaattcc tagaggttct
    56161 ggaaatgaaa aaggcataag tgatttttta cttagctttg gtaaaaattt aggtcttgaa
    56221 actattcagg atgaaagctt aaacataata ataagaaagc ctgctacaaa aggatatgaa
    56281 aattgtccag gtgtagttct tcaaggacat atggatatgg tttgcgaaaa agaaaagaat
    56341 gttgaacatg attttcttaa agaccctata aaattaagaa ttgatggtga catgatatat
    56401 gctactggaa ctactctagg agctgacaat ggtatagctg ttgctatggg tatggctata
    56461 ttagaagata atactttaga gcatcctgca ctagaagttt tagttactgt taatgaagaa
    56521 gatggtatga atggtgcaga tgcactagac cctagcttaa ttaaaggtca atatatccta
    56581 aatatggact ccgaggagga aggatactta ttagttagct gtgctggtgg taaaacttgt
    56641 gttgttagtt tacctgttga atacaaggaa gttaaaggtg acaaacaagg attattagtt
    56701 gaggttactg gactattagg tggacactct ggtatggaaa ttgttttaca aagagcaaat
    56761 gctaacaaag caatagctag agtattaagt gtattgaatg ttgattatga attagcttct
    56821 gttgatggtg gtactaagca caatgctata cctcgtgaag ctaaatgtgt aatagctgtt
    56881 aataaagctg atgttgaatc tgctaaaaaa caaataaatg acattttaac tgcatttaaa
    56941 catgagttta ctacttctga ccctggcatg acttactcag tagctgaaac ttctgtagac
    57001 aaagttctta ctaaagattg taaagaaaaa gttgttcaaa tgtcttgctt aactcctcat
    57061 ggagttcaat cagtaagtct tgatatagaa ggattagttg aaagttctac taacttcgct
    57121 ataattgaaa ctaaagaatc tactattgaa tttttaactt ctgttagaag ttctgttatg
    57181 tctattagag atgaaatcgc tgatagaata agacttttgg ctcaagcttt aggtgctaat
    57241 tacgacctta tagctcaata cccagcttgg gaatttaaaa aaggctcaaa attagaaaaa
    57301 atatgcagtg aaacttatga gaaattaact ggtaaagttc ctactgttat ggctctacat
    57361 gctggtcttg agtgtggatt attacttgat aaacttcctc atgctgaagc tatctctata
    57421 ggaccagata tgtttgatgt tcatactcca aatgaacatg ttagtatccc ttctgtagct
    57481 aatgtttggg attatgttat tgaaatatta aaatctatga accaatatta aatttaagtt
    57541 ttgattctaa gtagatttta attttaagta atctatataa aattaactct gtaaattaat
    57601 actactgtta gtataatatt tactttcaat attaacttat agaaataaag cctaatgata
    57661 gataataaca tgtatcatta ggctttattg taatttaaat attattaagc tttattctgt
    57721 tttaaaatta attcttatac tattttaaat ctatttcttc cttgtctctt agaatcataa
    57781 agagcattat ctgctatttg atacagttca tcatactctt gaccaggctt tgctataact
    57841 acccccatac taatagataa actttctcca tttggcaact taatgagatg aatatgattg
    57901 tatacatcat tacatttatt aataagttct tccttattta ttatatcatt gatataaaca
    57961 ctaaattcat ctccacccaa acgacctact atatcatttt ttgcaaaact ttcatcaagt
    58021 acctttgcaa catcaataag tactttatct cctaacaagt gaccataagt atcattaatc
    58081 gacttaaaat aatcaatatc tataatcaat aaagcaccat ttttttcagt tgataaattc
    58141 aacaaatttt gtgcagttaa ttttctaata tatgctgcat tataaatatt ggttaaacta
    58201 tccctttgag ccttatctaa caatctattc ttttcctctt tttcagaatc aatattacat
    58261 attttcccga ttacatacat tggtattttt ctatcattat aaattatttt tgaagtaact
    58321 ctaatccaat gaaaagtatc atcaagcata atagaataca tttcagttgt tccattttct
    58381 tgtgatttta ttacatcaaa aaacttttta ttatattctt tccttatttt atctctttca
    58441 ttttctatat tgccattttc actttcctta tcatttttat ccaaaccata ataagtctca
    58501 ataccctttt ctggcataga aattatcaat ttatcttgct tataatcata ctcaaaaaag
    58561 tattcacttg tcatttcata caactgagta tgttttttga gttctaaaga tatcttctcg
    58621 ttcatacttg tacgagtatg caaaccaaat gccataaatc caataataca aattaataaa
    58681 ctggctacaa taaaaatagt ctcaattgga ttctgttgca taatataaag caacgagaag
    58741 tcttgtctat atgtagtatt ttggtagaca attgattgca ttttttctga tgaaatactt
    58801 ataatagctt tattaaatat attcaataat tcttgtttat cttttttaat tataccaaaa
    58861 caaatactct ttgctttata agtttgagga actagacgca catttttata cttaggttga
    58921 ttcatatagt actgcataga ataaccttcg ccataagtgt aatctgcata gcctttatta
    58981 acagcttcta tacactcttc taaattatca taccaaacta tattctcttc aaactgacca
    59041 taataattaa tacctttggc tagagctaca cgttttccat ctaaactatt ctcatttaat
    59101 ttattattaa tcatcatagt atattgagta gaaagaaaag gccgagacat aactatatta
    59161 tgttcacgag agtattcata atcataaatc attcctgcta caatatcaat ttcacgcttt
    59221 ttagtcatgt tttctaaatc ttcttgagat tttacaggca caagttcaaa ttctaagcct
    59281 gttttatcac atatatgatt taacaaatca attgatatac ctcttaattc acctgtatct
    59341 ttatctatat tttgaaatgg tggtttgttt aaaagtactc ctacttttaa tttttctgtc
    59401 tctttaatgt aatcagtttc ttcatcagat aaaaacattt gattgttctc tggtgtaaag
    59461 tatttttcat ataaagtagt tgaaaaatat gggtctttct gttcaatatt attaattgct
    59521 gagttaagct tttgagttaa atttgtacta cctttaggag taatgaaata aaatggtttt
    59581 gatgaaaatt ttgctacagt acgtacacct tctagtgggt tcatactaac attaagaagt
    59641 acatctgctt taccactctt tagtgcttct agttgctcat catttgtttt acaatatacc
    59701 aattcaggtg acataagatt cattttacaa tactcatcta actctttaag tctagtatca
    59761 gaattttcta ttacagcaat acggattttt ttcacatctt gtgaactcat tatgttatca
    59821 atatctgtat tttcatataa tgcttgtagt actgtatttg ctactccata actatttcct
    59881 gcataattat atattttttg cattggctca ttgtataaca tacctcccat tatatcaatt
    59941 tcaccatttt ctaacatctt cattaatttt gtaatagatt catttatctc tccaggaact
    60001 tgaacaaatt cataattcca tccagtatac tgtgcaattt ctagtaaata ttcatatgta
    60061 tacccaaaat agttaccttg ctcatctatt tcagttaaac ctttttgaat aggataagca
    60121 acacgaatgg tacgattatc attacctata gcgttgatac caaaagaaaa tatgcaagaa
    60181 gtgaatatag atgtaattac aataattaat aaaagtaatt tttttaaatt cactacacaa
    60241 tcctccatat agttaagatt tacagtataa attactgcat aaacttgtag acatgtaaaa
    60301 atagattagt atataaaagg atatataaat ctacttagaa atttaaatat ccttaatata
    60361 tacaatatat ttaaattata actcatttat atgtctatta caacaaattt accctgctaa
    60421 atacctactc tatatcccat aattttacaa gttgtagtga agtttaagtt ctatctcacc
    60481 tcaaatttag cagtgtttct atttacagtt cttttatatt tcacatctgg ataacccaat
    60541 ataaatgaag tgataacagc ttcgttctcg ctcattccta acagttcttt tatctttggc
    60601 tctacatttg atgccataac aaaaaatcca ttataacaaa ttcctaatcc ttgagaatag
    60661 gccataagtt ccatattaga tgcagccagt cctccatcta cataagcact tccacctaga
    60721 gacatatctc ctacaactac cataagtagt ggggcatcat aaaataaaga atcatttccg
    60781 ttctctttat atcttttgta cattttctta aatgtatttt tatagataga acgtacaggg
    60841 tcattgtcat cagtatctaa tgccaaatta taaagacctt gtattgccag ttctttcact
    60901 tcttttagct tttcttttac taatatgtat cttataggct gtctattacc acctgttggt
    60961 gtgtatctac cagcttccac tatgtttttt attttttctt cttctacctc tatatcttta
    61021 tattgtctta tacttcttct aaatttaata aaattcaata acttttcggg ttctaattca
    61081 aaactttcac gattgtattc tattacttca tttttatcaa atccttgcat ttctattgca
    61141 tctgttgggc aaattgccat acagtgacca cagttaatac agagaatatt tttaaccttt
    61201 gctttatcat ccttaacttt tattgcattt acaagacagt ctgattcaca catcccacag
    61261 cctacacatt tttctaaatt tatgtctatc attccaaatt attcctcctt ttaaaaaatt
    61321 tactttagta taaaacaaat agttgtctaa gtcaattttt atttttttaa caatatacta
    61381 gccttaacta cactttaatg gagaaaaata tacataaatt ggaacttaaa ttagaactta
    61441 ttcaaagtaa aagataaaag aagtagatgt ctaaaagtga actttttagt taattagata
    61501 ttctttattg tatgaaatca agtggatatt tatcatttca acaataaaaa aggcttacct
    61561 ctattttgga tatgtccctg tcaagtagac atactaaaaa aaggctatct ttatgcactg
    61621 agatagcccc ttttcccaac tactattgtt tatcttaata ttagtcaata aatttaattt
    61681 gctataacct gtaagttaca ttttaatttg atgtaacttt aaattacatt tttaagtagt
    61741 atctttaaat tatattctta aaatatatca ttaaactaca ttttaattaa tctaaaaact
    61801 atatcttaat taatctaaga aacttacatt ataatctttt agtttcccat tatcatatac
    61861 aatctttgca ctaaagatat ttccagtctt agcccaattt aagaacagcc tgtcaccttc
    61921 ccacatattt aaatcgaata ttttatcatt atcaacccaa attaaatttc cttctttaca
    61981 atcatttaaa tctttttcag ataattcacc ttcaaactca tctgagaaat acaaaaacat
    62041 ataccaatct tcttcatctt taaattttgg aaaagttatc aaccctttat atgacaatga
    62101 tttaagagta agaccagtct cttcttttac ttctctaatt acacattctt ctggagtctc
    62161 tccttgctca aactttcctc caactcctac atacttacct tcatgtatat catctttctt
    62221 tttatttctg tacaacatca aagtcttgtc atctttttct atataacaaa tagttgtaag
    62281 tttcatgtat ctcgccttgc tttctcttta tattctcaac taattatttt cagcactttc
    62341 aagcacatca cttatattct tcattgcatt aagagaaagc tctgcaaatt catcaaatgg
    62401 aatccctata tcttctatac ttctcattgc atctctattt acatttgaag caaatctcgt
    62461 ttctttcatt cttttaataa cagacttagt ctttacactg gtaagttttt tatctggata
    62521 aactaaagct atagcagtta taaacccagt tatagggtct gctgcatata ttgctttttc
    62581 cattaggcta gttcttgtaa ctcccattcc atcatgatga ccaagtattg ctctatacat
    62641 ttcttcgtca ccgaagtttt cttttttaag cagttctact gttgttgtag catgtccttc
    62701 acatatttct cctggctttc ttccaactat atctgaatcc aaatcatgta aaagacctgc
    62761 cactgcccac tcttcttctt tttctggctc tagtcttttg gctaattctc tcataacagc
    62821 ttcaacagca taacaatgtt ttctcattct atcagtttct aaatacttaa ataaaatttc
    62881 taaagcttct tctctcattt tcaccaatcc ccctgttttt tcacatatat gatattttta
    62941 tatattaata cacataaatt caagctttta tatatattca tgtatatttt tcatgttata
    63001 tctattctac acctttatag tagtgtcctg caactgttcc aatttcatct aatttcttat
    63061 acaagtctgt agcctttttt ccaagtttat aattattact cagtacctca atgtgagctt
    63121 caataacctt tttaaccatc tcactatctt caactgtaaa atctatccta aatacatcta
    63181 ttccaatttc ctctaactca tatagattgt ccaacataca agtaaccttc gaattgtaaa
    63241 ttgtacttct acagaatata tcttgtgtta tcctataact tgcatccgta aagtctctta
    63301 aagcataact actttcctta catttagcaa ctctcttgtc ctttttacaa tctctaacaa
    63361 ctactcccat aggacagtat tctgtaacca tcataggagc atatccatat attactgctt
    63421 caatttctac atctgtatat tttaaagttt gtttaatttc atttaagttt agttcttgtg
    63481 acaaacaaac tgtacttgct ccctcttctt tgaagtgatt tatactttca ctattgaatg
    63541 catttaagta gcaatctata tttaagtctt ttttcttaaa gtattccata gagccccagt
    63601 taccaatttg aaccttatta attcctttta tattatccaa tatctcaaat tgcttgtact
    63661 ctttatttct aacaatcctt ggtgctgaat agattaattt tttgtcagtg actgctgtat
    63721 tatagtggtt cttattcaaa gtatctattt tacttgtatt tgacaaagta tctatgttat
    63781 ttgtatttga acccattagt tctttaggag tacctaaaga cgaagaagta tctaaatcca
    63841 tagaaatact tgaatctata gaaatatttg aatctataga aatacttgag accatttgta
    63901 aagcttttga taatgtattt atatcttcat aatagattaa atctacatta taatttaata
    63961 ctgcttctaa ttgctccaag ttcttaactt taactctaat cttaggagct gtatcaagtt
    64021 ttttctgttt atttactcta tttggctggt attttaatct attcttctta aattttctat
    64081 cttttatctt tattctttct tcatctaaaa gctcaataca atcccttctc atctgattta
    64141 acacacttat aggcatactt acaccttcat ccaggtcaat ttctatctct tttaacttat
    64201 atggtgtatt tccaagcttt tgaatttgtg tttctatttt ttctttactt aaagccacct
    64261 ttatagcttt ttcaactatt ttgtctcctt ctaccaccga tttatttcca caaaaatcac
    64321 ttataaaaag ctctggcttt ttacctagtt taatactcac ttttgcacgt atattagttt
    64381 ttatgaactc tttatcttgc tgaaatgtag cttgtactct atccattaat tcgctgtcag
    64441 aagtcttata tataagctga tttctctttg cttctccaac aaaatctaat tctatcaaat
    64501 cccctttatg tgctattgta gttatctctc catcctttat tattcttcca atagtacctc
    64561 cacctaagtt aattccatca cctttcttaa gcgtattttc tagcattact ctaagtcttt
    64621 tgttctttct attataatct aaaacttttc caatatatag cccttgatta ttaggtctat
    64681 tagagttcat tatatcctta ccaacttcac ctaatatata tccttttgta aactttctat
    64741 taaatatggt atacaaatta tttattattt cctcagaaat acttattttt ttcttatcta
    64801 caaattcatt aatcgcttct ctatatcctg aaaccacagt agctacatac tctggctttt
    64861 tcattctacc ttcaattttt aaagataata cacctgcttc aattatttta tccaaatctt
    64921 ctatagtact taaatctcta ggactcaaca aataatctcc attacttttt actacttctc
    64981 ctgtatttat atctatcaac tcatactttt gtctacatgg ctgtgcacac ctacctctat
    65041 ttccagacct attgcctatc atactactca taaggcattg acccgagtaa catacacata
    65101 aagctccatg tacaaaaact tctatatcta cagttgtatt ttcacaaatc cattttatct
    65161 catcaacatt taattctctt gctaaaacaa ctctatcaaa ccctacactc tgaaggtatt
    65221 ttacatcttc taaggaatgt gctaccattt gagtgcttgc atgtagttca aagtcaggta
    65281 atagtttttt tataagtctt gccattccta tatcctgtac tattaaagca tcaatatcta
    65341 tatcgtataa aaattttaca tactctacaa aatcttctat ttcatactgt tttatcaatg
    65401 tatttacagt aacaaagact tgcactcccc ttatatgaga gtatttaaca gcctcaatca
    65461 gctcatttct atcaaagtta tttgcagatg ctctagcact aaagtcttta ccacctaaat
    65521 acacagcatt tgctccgttt tgaactgctg cttttaatga atcaaaagag cctactggtg
    65581 caagtaattc tatttttttc atatttttct cctctattta tacttgttag gttaatataa
    65641 ttatatctat aacttaaata tttgtattaa atttatatat ttcttactat attttaaatt
    65701 cttcaatcaa tttatatatt agttatttat atttggttca tttgagttaa catatacatt
    65761 atttactata tttagtatat ttctattaac ttatatattg attactgtat tttaaattct
    65821 tcaattaatt tatatactgc ttactaaatt taaaacattt taattaattt
//
LOCUS       DAEORM030000018        58867 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.018, whole genome shotgun sequence.
ACCESSION   DAEORM030000018 DAEORM030000000
VERSION     DAEORM030000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 58867)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 58867)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 58867)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..58867
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.018"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            195..1271
                     /locus_tag="KRH23_001575"
     CDS             195..1271
                     /locus_tag="KRH23_001575"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004177 - aminopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M24 family metallopeptidase"
                     /protein_id="HHS5224856.1"
                     /translation="MKAQRLNAVLEQMKKDDISQMLVSDPTSIFYLTGVLIHPGERLL
                     ALYLNLNGNNKLFINELFPVSEDLGVEMVWFNDTQNPVEIITEHIDKNATMGVDKNWP
                     ARFLLNLIELGGGSKFVNSSYIIDTLRMCKDEEEKELMRIASKLNDKAMEQLKATVSG
                     ELTEKQLVGKLSKIYEDLGTDGFSFDPIIGFGPNGANPHGEPGNALVKPGDAIILDIG
                     CIKDNYCADMTRTVFYKEIPEKGREIFEIVLEANKRAEAIVKPGVRFCDIDAAARNYI
                     TEKGYGQYFTHRTGHSIGLEVHDKGDVSSINTDTVQPGMIFSIEPGIYLPGEFGVRIE
                     DLVLVTEDGCEILNKHDKEICVVG"
     gene            complement(1388..2230)
                     /locus_tag="KRH23_001576"
     CDS             complement(1388..2230)
                     /locus_tag="KRH23_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008289 - lipid binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HHS5224857.1"
                     /translation="MDKIKLIVDSACDLPDDIIEKYNIEVVGLNVSFGEESYISGKEI
                     DNETFYRKMSESKVLPKTSCPSPDKFLEAYHCQEESVLVINISSGLSGTYNSALLAKD
                     MFEKEGNNKKVEVIDSLSGSIGIGQLVLKAAILIKEGKEIEEIVSIINKYKDNPPFFG
                     TLETLENAIKGGRINPIAGKIINTLNFKAIIQVADGVVTPIDKARGEGNSLKKLITLV
                     ESKIKDKEEKVLFIGHANCPEKAQKVREVMEKDVKYKDVVICEIGSVMGTYTSKGAIL
                     ITAI"
     gene            2414..2986
                     /locus_tag="KRH23_001577"
     CDS             2414..2986
                     /locus_tag="KRH23_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HHS5224858.1"
                     /translation="MKTNNMKQAILSSATNLIAKNGVQNTSLADIAKDVNISKGTLYY
                     HYASKDDIIYDIADTHLEVITSAILNCVKNVKSKNSQIEMVNLILEKISTIESRGRVH
                     MYLICEAITSNNDLKERIRLKYIEWRTTLKSEIVESLEKYNSSENEQDAESFSFLLMS
                     IVDGLVVQSLLKTEKIPYENIASFLVNHWI"
     gene            complement(3149..3421)
                     /locus_tag="KRH23_001578"
     CDS             complement(3149..3421)
                     /locus_tag="KRH23_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224859.1"
                     /translation="MLRERFVVRNHHNPHTSGCCGTGGEGCCGGDNHEHSHQHSHSHG
                     HEHEHVNGVGHDHNHDDGFSGTHEHSHEHTHTHGHEHSDGHTHEHK"
     gene            complement(3548..4420)
                     /locus_tag="KRH23_001579"
     CDS             complement(3548..4420)
                     /locus_tag="KRH23_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HHS5224860.1"
                     /translation="MYGESKKLSIDNNIFLQYCLIILGMILSTLGINLYLAPAKLLSG
                     GVAGICVILYKLFGINQGISSFLMNIPIFIIARKYFDNKFLLISFVNMLLFSLALGLT
                     QDIAKYFPIDDTMLQCIYGGALTGIGMGLTFKARATAGGLDIIAAIMKRKYDIPMKNT
                     FLFINFFVVCAGAFLFGAKLVMYTLITMYIISFTMDIGKDCFDRKKSILLISNKYDEI
                     SKVIMNKMGRGVTFLEAEGAYTQNKKKMIYCIISANEIGKFKDLIYDMDSEAFISVNN
                     VEEVKGGGFKDKFL"
     gene            complement(4716..7823)
                     /gene="ileS"
                     /locus_tag="KRH23_001580"
     CDS             complement(4716..7823)
                     /gene="ileS"
                     /locus_tag="KRH23_001580"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004822 - isoleucine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006428 - isoleucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HHS5224861.1"
                     /translation="MAKFKPLVDSSVKQAEAQVFDYWKDINILEKTLEKGKDDPSFVF
                     YEGPPTANGNPGVHHVLSRTLKDSVCRYKTMSGYQVKRKAGWDTHGLPVEIQVEKELG
                     LTSKQQIEEYGIAEFNQKCRESVFSFEKQWRIMTERMAYEVDLDNPYITLDNNYIESV
                     WWILNKFNKEGYIYEGHKILPYCPRCGTGLASHEVAQGYKEVKTNTVIAKFKKKDADE
                     YFLAWTTTPWTLPSNVSLTVNADVDYLKVKKGDEVYYVSKPLADKVLGEDYEVLEEMK
                     GKDLEGLEYEQLMPFVEVDKKAFFITVGDYVTTEDGTGIVHTAPAFGEDDYNTGKRYD
                     LPVIQPVDETGKFTSTPWEGRFVMEDGLDVEIIKWLASENKLYSKEKVVHNYPHCWRC
                     QTPLVYYAKPSWYIEMTKLKDKLIENNNGVKWFPSFVGEKRFGNWLENLNDWAISRTR
                     YWGTPLPIWRCECGHTDSVGSRAELAEKAIEDVNPETVELHRPYVDDIHLKCEKCGKP
                     MTRVTEVIDCWFDSGAMPFAQHHYPFENKENFDQLFPADYISEGIDQTRGWFYSLLAV
                     STFVLGKAPYKSVLVPDLVLDKDGKKMSKSRGNTVNPMELFDQYGADALRWYLLYVSP
                     PWTPTKFDMDGLKEIQSKFIGTMKNVYNFFTLYANTDDINPTEFFVEYKDRPELDRWI
                     LSKFNNLMKDVEENLAIFELNKTLRMIQDFINDDLSNWYIRRSRRRFWATELTEDKKA
                     VYNTTYELLHGLCRAIAPFAPYMSEEMYRNLTGEVSVHLAEYPKCNEELVDTKLEEKM
                     DLAKNLVTLGRASREVERIKVRQPLQKVLVDGKFEDTISDVVDLIKEELNVKEVIFAK
                     DLDEYMNFSLKPNFKEAGPLLGSKMNLFVGALSKLNAHETANKLEKGETLTVDLDGEA
                     FEFNKDLVLIGITAKEGFNVSVENNLFVILDTKLTEELINEGYAREFISKVQQLRKSN
                     NFEVLDNIVIEYCGDDEIAKAVDHFNEYIKSETLALEINRVDDKSLEEQNLNDHMTGI
                     KVIKK"
     misc_binding    complement(7916..8148)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(8323..8850)
                     /locus_tag="KRH23_001581"
     CDS             complement(8323..8850)
                     /locus_tag="KRH23_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HHS5224862.1"
                     /translation="MLTPIEIENKEFKKGLRGYRDEEVDEFLDIIKEDYESLCRENTA
                     LKEKLGLYQDQVNKYENIEETLKATLITAQSAAEDTCSAANKKAKIIVEEADLKARQI
                     IEQANNRVIEIRKEYDALVKEFKIFRNKFKSLLEDEIRSVDEIFYDVDEKCVNAFEGT
                     TVYNYSNDEAATTLE"
     gene            complement(8885..9670)
                     /locus_tag="KRH23_001582"
     CDS             complement(8885..9670)
                     /locus_tag="KRH23_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HHS5224863.1"
                     /translation="MDKLKLTNHIKDIDLKNKMFKVIDKANSCIKNYDVKSTEFLNPY
                     EVKNAVAILNSTNEIKYSVDGGYEQAERSTVFIYPFYMEYEDIEDTLRFLQIEGNFKF
                     KNISHKDYLGSILGLGIKREKIGDIIIHDSFCQVVVSSDICDFIIVNLEKVSRNNVIV
                     KEISRENIVNSSSKYKEVSFTVSSDRLDCVISGIYNISRQDSAKYINGEKVHVNYEKI
                     TSTSKIVKNDDLISIRGKGRAKVTQIGDITKKGKIKVQARLIV"
     gene            complement(9680..9937)
                     /locus_tag="KRH23_001583"
     CDS             complement(9680..9937)
                     /locus_tag="KRH23_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HHS5224864.1"
                     /translation="MGTIRIALYYLLDIIAWMIVIKSLMTWFPNGRQSKIFDILENLT
                     EPIEGPIRSIMYKYTNGPIDFSPLIAIVLLMFLRQLVLVIF"
     gene            complement(9956..10414)
                     /locus_tag="KRH23_001584"
     CDS             complement(9956..10414)
                     /locus_tag="KRH23_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000917 - division septum assembly
                     [Evidence IEA];
                     GO_process: GO:0043093 - FtsZ-dependent cytokinesis
                     [Evidence IEA];
                     GO_process: GO:0090529 - cell septum assembly [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HHS5224865.1"
                     /translation="MSNGIISKFKNWIVDEEEDYIEDEYESGMDDIVQEEEMNSGFST
                     AKANKIVNLHTTSQMKVVIVEPKVYDEAATIADHLKQRRAVIVNLEGLTNSEVRKSIF
                     NFMNGAVYVLDGSIQKVSKSIFILAPNNVDIDANMKKELESKAFFPWQNK"
     gene            complement(10454..11158)
                     /locus_tag="KRH23_001585"
     CDS             complement(10454..11158)
                     /locus_tag="KRH23_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HHS5224866.1"
                     /translation="MGSIKDNLSEIRNKIDKAAKKVDRDSKEITLLAVTKTVDVDLVN
                     EAMREGITSVGENKPQELARKYDIIGDKLNWHLIGTLQTNKVKYIIDKVCMIHSLDRI
                     ALCEEIQKRAEQINREIDCLVQVNISKEESKHGLDREEVVDFVKEVSEKYKNIKIKGL
                     MTMAPFIEDEDEIRGVFKGLKDLSKQIKELNIHNVGMDVLSMGMSHDYEIAIEEGATI
                     VRVGTSIFGERNYNKK"
     gene            complement(11168..11803)
                     /locus_tag="KRH23_001586"
     CDS             complement(11168..11803)
                     /locus_tag="KRH23_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family efflux transporter periplasmic
                     adaptor subunit"
                     /protein_id="HHS5224867.1"
                     /translation="MKKVKYTRLVILGILIYLVFNILVMIISKNVDTLVLKNEKVDAK
                     IHVKGTIEKDANDQSNYLSTYISKEDSNNFEKNQNVIIEYHEQKLDAKVYKIYENNNK
                     IMVKLKISNQIVANQDTSVEEFDIIYNQMECLKIPKTSIKTKDNKRGVYVIDEQSQSV
                     KFVILEGITYENESSVFVDYYKNDINGVTSVNLYDKIILRPNSINTNIRIK"
     gene            12184..13224
                     /locus_tag="KRH23_001587"
     CDS             12184..13224
                     /locus_tag="KRH23_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HHS5224868.1"
                     /translation="MSEILLGTGLLLLVLCCFTIFSYKAPYGMKAMGALANAACATFL
                     VEAFNLSLLGDVLGMEFFRNVGAANGSLGGVAAAILVPLALGVSPVYAVLIGLSCLDF
                     SILSGFVAGYFVSFLIKFIEKKVPPGVDLVVVILLCAPLSRLIASNVDPLVNSTLLQI
                     GQVLIEATNISPIIMGIILGGLITVVGTSPLSSMALTSIIGLTGLPMAIGALGAFGSA
                     FMNSTLFAKLKLGSKKDIISVAIEPLTQSDIISANPIPIYSTNFFGGAFSGIIVALMG
                     LVNMTPGTATPVAGFAIMFAYNPVQQVLITAGLCALFNVIAGFLGSKIFSTFKVLTAG
                     EIRGTDVEEEIA"
     gene            complement(13687..15042)
                     /locus_tag="KRH23_001588"
     CDS             complement(13687..15042)
                     /locus_tag="KRH23_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HHS5224869.1"
                     /translation="MNVGNILETIKMIDEEQLDIRTITMGISLLDCIDPDGDKAREKI
                     YNKIMSSAKDLVKVGKDIEREFGIPIVNKRVSVTPISIIAGATDENDYVKFAQTLDKA
                     AEDLGIDFIGGFSALVQKGYTKGDKILIKSIPKALASTNKVCASVNVGSTRCGINMDA
                     VKEMGEIIKETAELTKDAKGFGCAKLVVFCNAVEDNPFMAGAFHGVGEADRIINVGVS
                     GPGVVKRALEKVKGEPFDVVSETVKKTAFKITRVGQLVAKEASSRLDVPFGIIDLSLA
                     PTPAIGDSVANILEEMGLEVVGTHGTTAALALLNDAVKKGGVMACSHVGGLSGAFIPV
                     SEDAGMIDAVIKGALSIDKLEAMTAICSVGLDMIAVPGNTTAGTLGAMIADEAAIGMI
                     NNKTTAVRIIPAPGCDVGDMVEFGGLLGRAPVMPINTNSSELFTQRGGRIPAPIHSFK
                     N"
     gene            complement(15068..15337)
                     /locus_tag="KRH23_001589"
     CDS             complement(15068..15337)
                     /locus_tag="KRH23_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HHS5224870.1"
                     /translation="MKAILTVIGKDKPGIVAGISDELYKQNINIVDISQKILQDYFTM
                     IMIVDLEKSLNSFEKTVEDLVERGKKLSVDVKIQREEIFNSMHNL"
     gene            complement(15627..17582)
                     /locus_tag="KRH23_001590"
     CDS             complement(15627..17582)
                     /locus_tag="KRH23_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224871.1"
                     /translation="MKKYEIFIFMSIIVLCFISFPHKVFGQEENCLEDFERWVQENKN
                     NKEEIVYTLSCDMVIDEEFRFYIPYDSNFTIDTNKYKILIKNHGRFIIDDNELNIIGE
                     GGKEGVIHIENGGSISIGINNIIATDGTALYVEEGGDLHIKSSYESVEKIKANGKDAI
                     GIYTENDIRILNKDIEVNGEHAIGVYSKGDVEIEETSIKAYSSNNESGLLKDNNKLAQ
                     SIISESKKVYIIDDYNELIPSIAEDSGYNIVKCCHRGIGVFSDEIKVSKDDKIENIKF
                     PKYMVLETSSGNRLDIDVEWDFTDYYEKLEKGENFNITGKFKTEMLNKEKIIINDDVV
                     PILNVSVIDKKPIDNLELEFQNTKNGYVAVLFYDMPYSASKVFVEYSSDGINWISEEQ
                     EDIRDQAILFFEDFKLRCFRVKVVGGLKEGYSNIVFKPGFIMGGGDNQETPDDEREND
                     DIDGDRGGGGRDDPDRDEDDNNQDGNNGNENNDSNNNQNNNNENNNNENDNSDEKQPN
                     TPKDDVESSTDSNENKNPHDIPKDGNKENNSDKEKGFYNKNSITENDDNYDLSSKSVF
                     GTNEHSFPYRESISNKNQDTNKNKSNISDYDGIINNNYKLESKEYNLKKDIIFLFCIL
                     TPIMIGSILIVNPDTRKSIIKFIKLKK"
     gene            complement(17765..19240)
                     /gene="spoIVA"
                     /locus_tag="KRH23_001591"
     CDS             complement(17765..19240)
                     /gene="spoIVA"
                     /locus_tag="KRH23_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="stage IV sporulation protein A"
                     /protein_id="HHS5224872.1"
                     /translation="MNNNIYEDISKRTQGDIYIGVVGPVRTGKSTFIRKFMEKLVIPN
                     IDNEFKKDRTRDEIPQSGSGKTIMTVEPKFVPADGVEIKIKDTVSLKVRMVDCVGYIV
                     EGALGHEEGGKQRLVSTPWSQEAMTFEKAAEIGTKKVIKDHSTIGIVVLTDGSVTGID
                     RKSYVEPEERVIQELKNLKKPFAVVLNTLSPKSEETSMLRSELEEKYEVPVLPMNVVE
                     MEEEDIEEVMEAVLYDFPLTEIRINLPKWVEGLERNHWIKSSIITTLKQSIIDIGKIR
                     DIEGIIQGFSELEFLEDTGVDNVELGEGVINIDLQTKQDLFYNVLEEKSGFKIEGDYQ
                     LLSLITRLSKVKNEYDKIESALIDAKIKGYGVVAPSLEELSLEEPEIMKQGKQYGIKL
                     KANAPSLHIIKADISTEVSPIVGNQNQGEEMIKYLMEVFEEQPADLWESNMFGKSLHD
                     LVKEQLQSKLYTMPEEIRVKMQKTLQKIVNEGSSNIITILL"
     gene            complement(19412..20707)
                     /locus_tag="KRH23_001592"
     CDS             complement(19412..20707)
                     /locus_tag="KRH23_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015112 - nitrate transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HHS5224873.1"
                     /translation="MSVEVNKPSIWKNFKVLIILFVAGAFIYALPYLKNYYYDTFAQA
                     FNLTNTQMGSLGSIYGLLAMVSYLFGGFLADRISARKLLSGSLIITGISGLVLTLYPP
                     YIVVFLIHALWGITTILTFWPALVKAVRMLASENEQGKAFGFMESGRGITNAIHLSLV
                     LILFGYISSKVSDKSGLTAIIVLYSAINVIVGVLVFFKLKDNEKEVSAKFDKEAFFAV
                     IKMPHTWIITIIMFCSYSANMSFYYFTPYSTEAFGATVVFASAISILAQYCRPVASAA
                     SGLLGDKVGSSKIISYGFILMIAGLLGVIFTPTKSSMIYILLIGCVVIYVSMYAIQGL
                     HYSLLEEGNYSLSISGTAIGIVATLGYLPEVLCPLAAGKILDAFPGVTGYRYYFIVLT
                     IVAIIGLVFTFIWMNMTKERRKELIEMNNNSNENTTKVS"
     gene            complement(20891..22336)
                     /locus_tag="KRH23_001593"
     CDS             complement(20891..22336)
                     /locus_tag="KRH23_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015171 - amino acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HHS5224874.1"
                     /translation="MSLNKFEIGGITVKKKIGFWDLVFMNISALFGIRWIAKSTASSF
                     GLGLGSIPVWLLFAFIFFVPASLICAELAATYPKDGGLGEWVKQAYGEKWGFMVSWLN
                     WTSKIFWYSSFLTFLAINIAYMLGNPDLSNNKMFILALSLIIFWLLSLVSTRGMAFGK
                     FFTNTGALGSTIPAILLIVMAFMSVVILKKAPSASIYTIQNIIPKIDANSLVSISAII
                     FALSGAETTANFITEMDNAKKNFPKAILTVAVLIGGIYILGSVAITMILPPDKIAAST
                     GILDALAKVAQDLGIGSWFIRIVAFGITLSVLGALILYIAGPVKMLFGNVREGVFPKQ
                     LTVTNKYNIPSNAVIVQAIIVSLLLVGTNLLPSVDNIYNVLVTMTALTALFPYVLLFT
                     SYIRLRKTRPNEERPYSIAKSDSVCINIARMVLVVTVVGILFSTAPVMETLKDNIIYE
                     IEMIGGGLFVIITGLMLWKNYEKKISNNSGR"
     gene            complement(22352..23491)
                     /locus_tag="KRH23_001594"
     CDS             complement(22352..23491)
                     /locus_tag="KRH23_001594"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004177 - aminopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M24 family metallopeptidase"
                     /protein_id="HHS5224875.1"
                     /translation="MSNNMRLERLRKYMNEKSIEIALIFEPDNQFYISGFKAITYSRP
                     IVTVVTQDKIELIVPGLEELHAKEVAKVDNVYVYYEIPEMKEHGISHKHYLDIILNKY
                     PKGTTVGIEKDIVSASFSEYITDKSFAIKDVGSKIFEMRYVKDAKEIEFLKIAGYLSD
                     IGIKGSLENVRVGMSELEFDVAGDNALLKYVSENYPDTYIGFANWTCSGIDRTAQPHL
                     DSNTRILQRGDIVIHSRQVWYENYRAENERTFIIGKPTERQKEVFKIAVEAQQAGLDT
                     IKAGIPARMVDEAARAVVAKYGLELYSNHRIGHGLGLSEHEEPYLRFDNELILEEGMV
                     FSMEPGIYIPGVGGFRHSDTAIVGKNGATIITNYPRSVEELILDI"
     gene            23810..24460
                     /locus_tag="KRH23_001595"
     CDS             23810..24460
                     /locus_tag="KRH23_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HHS5224876.1"
                     /translation="MTNKELQKKRILMYFIEAAQNIMENEGIENITLRKVADMAGYNS
                     STLYKYFKNLDHLISFASIKYFKDYNLNISRCIENVNDEYKKYIIMWKLFCKHSFDNA
                     QAFYQVFFNLSSDELSYITKQYYDMFPEDLGIHDSDISLMITGESIKERNKILLNNLV
                     DTGYIPAKDLDIINDIIISFYQNLLFLKKNTGKNSDDDELTMKMISSIEYIIKHAK"
     gene            complement(24617..25636)
                     /locus_tag="KRH23_001596"
     CDS             complement(24617..25636)
                     /locus_tag="KRH23_001596"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009331 - glycerol-3-phosphate
                     dehydrogenase (FAD) complex [Evidence IEA];
                     GO_function: GO:0047952 - glycerol-3-phosphate
                     dehydrogenase [NAD(P)+] activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0046168 - glycerol-3-phosphate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HHS5224877.1"
                     /translation="MEKVCVLGTGSWGSALALGLAKKGNDVSMWTRKEEQAKKINRTK
                     ENTDYLPGVLFPNNITISTDIEKTIKDCKVIVLAVPSQAVRSTCQKIKPFIKEGQVIV
                     NVAKGLEKGTGLRLSQVCEEELPQNPYVILSGPSHAEEVARDIPTTVVVASKDLKIAQ
                     MIQDLFMSPKLRVYTNPDIVGVELGGALKNIIAFGAGICDGLGYGDNAKAALMTRGIS
                     EMSRLGIAMGANMSTFAGLSGIGDLIVTCTSMHSRNRRAGILIGKGMSLEDTLKEVKM
                     VVEGITATEVAHDVAEKLDIDMPITNAIYSVIKKGSNPKEVGIELMMRSKKHEMEEVV
                     LGDDI"
     gene            complement(25667..26281)
                     /gene="plsY"
                     /locus_tag="KRH23_001597"
     CDS             complement(25667..26281)
                     /gene="plsY"
                     /locus_tag="KRH23_001597"
                     /EC_number="2.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008374 - O-acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006654 - phosphatidic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HHS5224878.1"
                     /translation="MEIFSYIIIAVVAYLLGNISTSYIVAKRIAGVDIRTQGSGNAGS
                     TNVLRTLGKRAGAMTFLGDVLKGVMAVLISEFAARLVGIDTLLAGYLAVICVVAGHNW
                     PAVLGFRGGKGVATSLGAMLAVNPVITLMCLAVFILVVAITKYVSLGSVVGIGCSPIF
                     MIMVKNKAGLIVALFLTASVIYNHRANIKRLLNGTERKIGQKKE"
     gene            complement(26316..27641)
                     /gene="der"
                     /locus_tag="KRH23_001598"
     CDS             complement(26316..27641)
                     /gene="der"
                     /locus_tag="KRH23_001598"
                     /EC_number="3.6.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HHS5224879.1"
                     /translation="MSISRPVVAVVGRPNVGKSTIFNKFAGKRISIVENTPGVTRDRI
                     FAEVEWLDKYFTLVDTGGIEPDSEDIILSQMRNQAMLAMDMSHVILFIVDGKAGITAA
                     DKEIAQLLRKTKKPVILVVNKIDSQSQFDNIYDFYELGFGTPFAVSGANSMGFGDLLD
                     EIVENFPAGLDTEYEEDIIRVAITGKPNAGKSSILNKILGEERVIVSPIAGTTRDAID
                     TYFEKNGQKFLLIDTAGLRRKSKIYETIEKYSVIRAMSAVDRADVVLIVIDALEGVTE
                     QDTKVAGIAHDEGKGCIFVINKWDLIEKDNKTMSNYTKDIKEKFPFMMYAPIVFVSAK
                     TNQRMNKILDTVEYVSNEHSKRISTSALNEVIGEAVMLNQPPSDKGRRLKIYYGTQTD
                     IRPPKITLFINDKDLTHFSYQRYLENKIRENFGFEGTSIKFEYRQKNKK"
     gene            complement(27669..28997)
                     /locus_tag="KRH23_001599"
     CDS             complement(27669..28997)
                     /locus_tag="KRH23_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF512 domain-containing protein"
                     /protein_id="HHS5224880.1"
                     /translation="MEVNVKKVNNIISKVYKDSIAEEMGIEVGDLLISVNEQPIHDII
                     EYRFLLSDEYLDVEIQKKDGEVYIYEIEKDYDEDLGVEFTNPIIDQAKSCRNKCMFCF
                     IDQLPEGMRETLYFKDDDSRLSFLQGNFVTLTNMSEEDINNIIKYRISPINISVHTTN
                     PELRQKMISNKFAGKLYGIMKRLADAHIEMNCQIVLCPGINDGKELDRTIKELAQLYP
                     YVNSVAIVPVGITKHRENLVELNIFNDKSASKTIEQIHQIQQKYLEKLGTRFAFLSDE
                     FYILSNSELPGYEEYEGFLQFEDGVGMIRKLKTEIEEYLNILPEKILKREKKVSIATG
                     HSAYEFIQSMADAMMDKFKNLQVNVYEIKNKFFGETITVSGLLTAKDLKEQLEDKELG
                     EALYITRSMLKADEEIFLDNIELNQLEELMRIKIIPCLNEGKDFVDKILK"
     gene            complement(29235..29435)
                     /locus_tag="KRH23_001600"
     CDS             complement(29235..29435)
                     /locus_tag="KRH23_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capping complex subunit for YIEGIA"
                     /protein_id="HHS5224881.1"
                     /translation="MGMDIGLNEYTLAIVTLDKNMKNGGGCPIFYANDEKDLQNKALL
                     MSKCVGGMVHDMTNGTLIIVKH"
     gene            complement(29437..30369)
                     /locus_tag="KRH23_001601"
     CDS             complement(29437..30369)
                     /locus_tag="KRH23_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YIEGIA family protein"
                     /protein_id="HHS5224882.1"
                     /translation="MDRVFFVAVIIGITSRIIMLNLDQKQYPTQPNVLLSQLILAFVA
                     SSLGALLVPALINRSYTSITFLSLAAEQFRQVRANRRNTLQNLEEVQLVKRGAAFIEE
                     IARTYEVRNYMCIVTSFLTIGLYYVILAETKISEGMSLVISSICGLVLAFILKKLLTR
                     KSIGDIADVMPAEISFVDESILKVGDLKGITNIGLKSDREVYINRGVGIQIIPKNKDY
                     ANAGILFDSGQRQAIVYNIYSRLGLYGDYGEPSFVPLPRRNKEDESIMIAYLPVDKNV
                     EKVMEAVKSCPILSSSKGKNLSLKNYKIGKKGSA"
     gene            complement(30414..31346)
                     /locus_tag="KRH23_001602"
     CDS             complement(30414..31346)
                     /locus_tag="KRH23_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YIEGIA family protein"
                     /protein_id="HHS5224883.1"
                     /translation="MEESLLNANLFRHSFIVALVVGILCRGLVLRVTDKQYPSRPQDY
                     LEQIIISGLSASLGAIALPALIDKEFAALTFFAVAIQQFQGLAEQERITLKNIDNEEL
                     VPKGDAYVEEIASTYESRSYISLFSALVSSIVYIVFARKYGLSFFYCTILAIVSGAIV
                     GLIFRRFLRRNSIADIADIVPAKISFEGPILMVNGVIITNIGLESTREKYRNECLAIE
                     VIPRDLGAFGIVNDIGQRQAIIHNLFIHMGIDRDVDEVDIVAISKTNLEKSTVVIPYM
                     PILKDIDVMIDVVKSTPIIETSKGKQSDFSRKTL"
     gene            complement(31401..32690)
                     /locus_tag="KRH23_001603"
     CDS             complement(31401..32690)
                     /locus_tag="KRH23_001603"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="HHS5224884.1"
                     /translation="MEDLNSIYFFIVMLSIAIVILAVRYTITLRKYLKEFIYVSKKVS
                     NNEYHARLNISAKGELGELARNFNHMIKNMDKTLEEVQYKHLQLRSILKSISHGILAI
                     DVNGNILLINDEAKEMIKSEPNQLVEGHNINVVIKEEEILKQILQFIGSKDNETANIT
                     TKDDIVYKIKVDPVYLQNTNNVIIGSIVNIEDITKKVKLENMRSDFVANVSHELKTPL
                     TSISGFVETLKSNENIDVNTRNRFLEIIESESDRLKRLIDDILLLSFVENKDTLLMEN
                     VVVYDVFKEVYEITQHSASEKNIEVLYKCDDKSISILSNKDYIKQVFLNLVDNAIKYT
                     QDNGIVQVVVLKDEEKIVIKVIDNGVGIPKEDVERIFERFYRVDKARSRDVGGTGLGL
                     AITKHIVKSLNGCIKVKSELGIGSEFIVTILQKNFLK"
     gene            complement(32719..33411)
                     /locus_tag="KRH23_001604"
     CDS             complement(32719..33411)
                     /locus_tag="KRH23_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
                     /protein_id="HHS5224885.1"
                     /translation="MNTKVLVIDDEMHIVELLKFNLEVSNYEVSYSYDGFDGFIKAKE
                     IKPDLILLDWMLPNISGIEVLRKIRSDKDLKNIPVIMLTAKNMENDKVEGLEIGADDY
                     ITKPFSIKELLARISSVLRRYNLTSLGEENNILTTGNLKLDLSKHEVTKGSEKIELTL
                     KEFELLKLLIQNKGKVLSRNYLLDKIWGYEYYGETRTVDVHIRYLRKKIEDEDKSEKY
                     IETIRGVGYKID"
     gene            complement(33426..34187)
                     /gene="pgeF"
                     /locus_tag="KRH23_001605"
     CDS             complement(33426..34187)
                     /gene="pgeF"
                     /locus_tag="KRH23_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan editing factor PgeF"
                     /protein_id="HHS5224886.1"
                     /translation="MMKDYINIKNVQDIKEYVNLSDNCEELDEKLNSVNLVITCKNID
                     AKNREDMLKVCKECDLTFENLTSNSQIHSDIVNIVNKDTIGKRRDGDALITNLEKVPL
                     LLFTADCVPISIIDAKNKAIGLAHAGWRGTFSNIGHKTIKLMSECYKTVHEDLVCIIG
                     PSIGPCCYEVSEDLVEKFNTILTNNDEKFYIIKEGSYYLDLWKINEYMLRCSGVKKEN
                     IINLNLCTSCRADKFHSYRKHNKASERIGTVLQIK"
     gene            complement(34184..34645)
                     /gene="nrdR"
                     /locus_tag="KRH23_001606"
     CDS             complement(34184..34645)
                     /gene="nrdR"
                     /locus_tag="KRH23_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0140110 - transcription regulator activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator NrdR"
                     /protein_id="HHS5224887.1"
                     /translation="MQCPYCNYKESKVIDSRHTDLKSIRRRRECESCKKRFTTYEKIE
                     TTPLMVIKKDNSREYFDREKIKYGLLKACEKRPVSIDEIESIVVHIENEINKCFIEEI
                     ETKKIGEMVMDKLKELDEVAYVRFASVYRQFKDINTFVNELKSILIEKGDK"
     gene            complement(34667..34930)
                     /locus_tag="KRH23_001607"
     CDS             complement(34667..34930)
                     /locus_tag="KRH23_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YlmC/YmxH family sporulation protein"
                     /protein_id="HHS5224888.1"
                     /translation="MIRVSDIMEKEIINVKNGKRMGFIIDIDMDIHEGKVVSFTIFGD
                     GSRSFFSRGGDEEVIFWNDILKIGCDTIIVNIGSELSLDEFEI"
     gene            complement(35034..35807)
                     /gene="sigG"
                     /locus_tag="KRH23_001608"
     CDS             complement(35034..35807)
                     /gene="sigG"
                     /locus_tag="KRH23_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sporulation sigma factor SigG"
                     /protein_id="HHS5224889.1"
                     /translation="MQVNKVEICGVNTSELPVLKNKQMKELLLQIKNGDEEARQQFVR
                     GNLRLVLSVIKKFNNRGENIDDLFQIGCIGLIKAIDNFDLSQNVRFSTYAVPMIIGEI
                     RRYLRDNNPIRVSRSLKDIAYKALQVRERLIRTNSKEPTVSEIAKELELEVESVVMAL
                     DAIQDPISLFDPVYQDNGDAIFVMDQVQDKKDTDENWLQEISLKEAIKKLNSREKLVL
                     DLRFYKGRTQIEVADEIGISQAQVSRIEKNALKNMRKYV"
     gene            complement(35899..36621)
                     /gene="sigE"
                     /locus_tag="KRH23_001609"
     CDS             complement(35899..36621)
                     /gene="sigE"
                     /locus_tag="KRH23_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sporulation sigma factor SigE"
                     /protein_id="HHS5224890.1"
                     /translation="MLRLKERIISFITMLGIKLKIIKPKGIYYMGGANILPPPLKPEE
                     EMELLQKLETDESVKSILIERNLRLVVYISRKFENTGIDVEDLISIGTIGLIKAVNTF
                     KLNKNIKLATYASRCIENEILMYLRKNNKKKTEVSFDEPLNIDLDGNELLLSDVLGTE
                     NDEIYKIIEEEIDRDLLVMALDRLSDREKQIMELRFGLIDKGIEKTQKEVAGMLGISQ
                     SYISRLEKKIISRLQKEMKKFV"
     gene            complement(36646..37491)
                     /locus_tag="KRH23_001610"
     CDS             complement(36646..37491)
                     /locus_tag="KRH23_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-E processing peptidase SpoIIGA"
                     /protein_id="HHS5224891.1"
                     /translation="MVYIEYYVIENLVINYIIISCTSILTKRYNPKKNKLLGASLGGA
                     YSVAYLYPSMNILFTVPFKIIIMSIITLISFRSKSKKDYVHVALVFYLVNIFISGSTY
                     FIIYFTGISHLKISFLIACTYVSCELLKYIYKDLKMLKYIKELTKTININLLEKSFCC
                     KALVDSGNLLKDPISQSDVIIVKSSVLEGFIPEKLLNINYEDIDMKKAQEIIGSLDDK
                     TSGRVRIIPYKHAGSNKTSIIIGLKADYIEVDEQKIGNIILGISNFNDREYGAIMNPN
                     ILPGF"
     gene            complement(37808..39082)
                     /locus_tag="KRH23_001611"
     CDS             complement(37808..39082)
                     /locus_tag="KRH23_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HHS5224892.1"
                     /translation="MIKLKKVLSLVMVGILSVSILAGCSKKEDSKGKEGKEKLVVWSA
                     PLTDHDADAWKPIFEKFEKENNCEIEFQIVPWDNYAEKYATAISAGEGPDIGYMYAEM
                     FPQFIEMGAVEDLTPYLEKSGTSDNYLYLDDAKMMGGIYGLPIEAANPGVLYYNKDIL
                     EKLGEKPPKTWDDFKRICEKATKDTDGDGKIDQWGLAQGWGSKVFGSLNWNWYPYLWQ
                     AGGDIYNDDLKSVKFNNAEGLKAANFINDMKKYIPEDALSKDSNEMIESVFGPGKAAF
                     TIMLSSAATSTFDKSFPDLNWGYVTSLEDKTVGSFASVDDLTLMSACKNKELGFKLLE
                     YMLSKESMEAFHKEIPRAPVAKGEKYQGDPRFEEMVTRDKHMYRPLTVGPHGVEIYEY
                     LWKQLQMMIAGDITPEQALNESAKYANGLLAQ"
     gene            complement(39366..40523)
                     /gene="ftsZ"
                     /locus_tag="KRH23_001612"
     CDS             complement(39366..40523)
                     /gene="ftsZ"
                     /locus_tag="KRH23_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HHS5224893.1"
                     /translation="MLNFDVELEECAQIKVIGVGGGGNNAVNRMVEAQLKGVEFISVN
                     TDKQALYTSKAEYKVQIGEKLTRGLGAGANPEVGKRAAEESKDEIVKLLQGADMVFVT
                     AGMGGGTGTGAAPVVAGLAKEMGILTVGVVTKPFAFEGKIRMKNAEGGIAELKSKVDT
                     LITIPNDRLLQIVQKNTSMLDAFAVADDVLKQGIQSISDLIAVEGLINLDFADVTTIM
                     KDKGLAHMGIGSASGETRAIDAARQAIQSPLLETSIQGAKGVLLNVTGGPNLGLFEVN
                     EASTLVMESCDPEANVIFGASIKEDLGDEIMITVIATGFEGLQNGALDLDTKPKSSIR
                     SSLNTTVKQAVKEIEEEVIAEEKIEPPKKASIIEEDDDESMEIPTFLRRRR"
     gene            complement(40713..41066)
                     /locus_tag="KRH23_001613"
     CDS             complement(40713..41066)
                     /locus_tag="KRH23_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small basic family protein"
                     /protein_id="HHS5224894.1"
                     /translation="MLWVLGGLAFGVVVGYYIPFTYSMDYSIYMSVAILAIMDSIFGA
                     IKSNFEDNYDNVIFITGFIGNAILAILLTYIGEKLGVSLYYVAVLVFGMRLFNNLSII
                     RRYIISNIMNKKRKN"
     gene            complement(41165..41839)
                     /locus_tag="KRH23_001614"
     CDS             complement(41165..41839)
                     /locus_tag="KRH23_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DUF881 domain-containing protein"
                     /protein_id="HHS5224895.1"
                     /translation="MKKKIVILGAFILGVFISTYIKSLDPNRVYITLGQTESIESEVE
                     NTKKEIKNLKETLKKNKKTLNEYKEAKKNGNESIQTLMQKELEEVKELSGYSTVTGPG
                     ITITMRDSERELKDGQNPNDLIIHDIDILRVLNDLKKAGARAISINGERVLATSKIKC
                     SGATITVNDTTYGQPFIIKAIGDIDLLSAAINSPESYAKSLKDIYGINIKVQENNGNK
                     VNLFAK"
     gene            complement(41844..42542)
                     /locus_tag="KRH23_001615"
     CDS             complement(41844..42542)
                     /locus_tag="KRH23_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DUF881 domain-containing protein"
                     /protein_id="HHS5224896.1"
                     /translation="MKKRFINKSIIIGSIVLGVLVSLQLKIINIENRGMTTFKRGEQL
                     TEELKSLKKEKENLQSEVNSVKKDIETYRGKNNEGEQDILKSEIEKYETLAGYTDVEG
                     TGIKIEINSTKDLGNSDKNDSILYNYDLLLSMINKLNSAQASAISINDQRIVSNTYMY
                     LKEDKLYMNDTVIKEPIIIKAIGDSDTLASALNIKYGIVWEIETYYNAKVKVTKEDNI
                     EINGHSDINKAEGK"
     gene            complement(42565..43305)
                     /locus_tag="KRH23_001616"
     CDS             complement(42565..43305)
                     /locus_tag="KRH23_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0043093 - FtsZ-dependent cytokinesis
                     [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsQ/DivIB"
                     /protein_id="HHS5224897.1"
                     /translation="MKKRRKLNTNNVMIVLVFILMLSFCICIIVKSDLFDVKKIDVIG
                     NKRVTKSNIMKELNVNLNENIFAYNFKDMKNKLIKNPYIENVEIKRKLPNKIIISLKE
                     KEIFAVLKDEDNYCYIDKKGNLLEELRGSNESKKDLIVDVDYSIDDNKSIKFKNYKTK
                     ENVFKTLNYLKEEGIYRKINYVNLKKESNIEMLTRSNIKILLSNDDNLDYNISRVSKI
                     LIDLQNKNTNGGTINLNYGKLAVYSPEG"
     gene            complement(43575..44801)
                     /gene="murG"
                     /locus_tag="KRH23_001617"
     CDS             complement(43575..44801)
                     /gene="murG"
                     /locus_tag="KRH23_001617"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050511 -
                     undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HHS5224898.1"
                     /translation="MKVLLSGGGTGGHVYPAIAIANKIRDEHPDAEIIFVGTEKGIES
                     EIVPKYGFELKTVTVQGFKRKIDFDNVKRVFKLFKGLEQSRKIVKKFKPDIVIGTGGY
                     VSGPVLFNASMGKIPAIIHEQNSFPGVTNKILSKTVTKVLTSFEDSHKRFPEAAEDKL
                     VFTGNPVRKEILLSRKNIARKNLSISDEKRMVLCYGGSGGSRKINDAMRLVIKNMVNE
                     DIAFIFATGKSYYDEFMGSISDINLKPYQKVVPYLEDMANALAASDLVIGSAGAISLA
                     EITALGKPSIIIPKAYTAENHQEYNAKSIEKQGAGIAILEKNLTPESLNTAVFKLLGD
                     RELLVDMANASKTIGKPEAIDLIYDEIMKVYNSTQKSTSKKTKKEKVIKEVKEIKKET
                     TPSIEGQAKVIGIKKR"
     gene            complement(44819..45949)
                     /gene="spoVE"
                     /locus_tag="KRH23_001618"
     CDS             complement(44819..45949)
                     /gene="spoVE"
                     /locus_tag="KRH23_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein E"
                     /protein_id="HHS5224899.1"
                     /translation="MPKENLKKQIDIRMKTEFDGVVFYTTMLLVFVGIVMVFSASFIQ
                     SSFKHNDAYYFLKKNVIYAVLGFIVMIITSRIDYSFWKKNATAIGAIAVVLLLLVLTP
                     LGIEANGAKRWLGIGALTFQPAEIAKFATIILTAKLIEKNYDKIKSLTKGVVPLLVVP
                     GIFFALIILQPNLSTAGTVILVTFVMIFVAGMDMKIVFAMIGSGAALFAALVIAEPYR
                     LSRVTSFLDPFQDPLGKGYQVIQGLYALGSGGLFGLGLGKSKQKYFYIPEPQNDFIFA
                     IIGEELGLIGCIIVIMLFVVLVYRCVRIALKTSNVFACMVVIGIGAQIGIQAALNIAV
                     ATSSMPATGVALPFISYGGTSLTIFMGAVGIVLNISKHVKIN"
     gene            complement(46001..47356)
                     /gene="murD"
                     /locus_tag="KRH23_001619"
     CDS             complement(46001..47356)
                     /gene="murD"
                     /locus_tag="KRH23_001619"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008764 -
                     UDP-N-acetylmuramoylalanine-D-glutamate ligase activity
                     [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HHS5224900.1"
                     /translation="MDLKGKKVLLVGLAKTGISTIKHLDKLGASIIVNDIKDENKLRN
                     ILDELKSINDIKYILGHHPEDVDDIDMVVVSPGVPLDLPFILKLKNSGKYIIGEVELA
                     FKLSNNPIFIGITGTNGKTTTTSLVGEIFSRAKRDTYVVGNIGNPVIDTIETSSEESV
                     LVTELSSFQLESIDEFRPKVSAILNITEDHLNRHHTMEKYIEAKANIFMNQTVEDFCV
                     LNYDDEIVKSLADKCNAKVIYFSRTKKVNGGVYLENNDIIIDIDDKIKFLNKDDVSLP
                     GGHNLENCMAAIAIAYVCKIDLEVIKDVLMTFKGVEHRQEFVRNLDNVIYVNDSKGTN
                     PDSTIKAIQSYDRPIILIAGGMDKGSNFDELLETAKSYVKSLVLLGETASNIENCAKN
                     KGFNDIHIVKDMEEAVKTSYEISKSGDIVLLSPACASWDMYESFEVRGKDFKDNVNNL
                     K"
     gene            complement(47375..48343)
                     /gene="mraY"
                     /locus_tag="KRH23_001620"
     CDS             complement(47375..48343)
                     /gene="mraY"
                     /locus_tag="KRH23_001620"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008963 -
                     phospho-N-acetylmuramoyl-pentapeptide-transferase activity
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HHS5224901.1"
                     /translation="MMLGITELTYTALIAFLIVIIIGPIFIPMLRKFKFGQTVRDDGP
                     QTHLAKNGTPTMGGIIMIVAILITGLTRVKVSHDMAVGLICIAGFGFIGFLDDFIKIK
                     LKRSLGLKAYQKIILQVALSFYVAFYQYTSSSSASQLMIPFTDFVINVGILYIPIMMF
                     IIVAIVNAVNLTDGLDGLASGVTLIVSVFFMLFASSIAGNTEVAVLAAATVGACLGFL
                     GFNSYPARVFMGDTGSMALGGAVVAFSVLTNSVLIIPIIGGIYFAEALSVLIQVGYFK
                     ATRKRFFKMAPIHHHFEQCGWPETRVVFIFWIITVVLAWISIIAVF"
     gene            complement(48384..49757)
                     /locus_tag="KRH23_001621"
     CDS             complement(48384..49757)
                     /locus_tag="KRH23_001621"
                     /EC_number="6.3.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0047480 -
                     UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase
                     activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HHS5224902.1"
                     /translation="MECLTIKELVLATNGKLIYGDYNDCVSDIVIDSREANAQNAFVA
                     IVGENLDGHTFMKSAYDSGCKTFIKNESNGIKLESSDINLIEVKDTSLALGDISKYYK
                     EKFDIPFIGVTGSVGKTTTRDMIYSAISAKLNILKNEKNLNNHFGVPLTLFNLNKEHE
                     CAVIEMGMSGFNEIKYLVDIVNPKIAVISNIGLSHVEKLGSQEGILKAKMEITSNFDE
                     TNTLIVNGDDKFLSTLKEKEHVYKLKTFGFNKNNDVYCESYTMEEDSLTFICVINGKK
                     EEIFIPTIGEHNIYNAMSAILVGLCLNISLDYIKKGLKNFKGTKMRLDIIKNEKLTII
                     NDSYNASPDSMDAALKILGRYKGRRVAILGDILEMGEISEYGHRLVGKSSMNNTDIII
                     TIGENSVFIGEEAKQLGFNSANIYHFENREDVFNKLNELVKTGDTILVKGSRGMRLEK
                     IVEYLNK"
     gene            complement(49924..51903)
                     /locus_tag="KRH23_001622"
     CDS             complement(49924..51903)
                     /locus_tag="KRH23_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein D"
                     /protein_id="HHS5224903.1"
                     /translation="MRKVKRISKKRLVLVLILACALFFCLVIRTGYLQLMKGNWLSTK
                     ALEQQTRDIPIEPKRGTIYDRNMKELAVSVTKYTVWCKPVEVEDKKEAAEKVAEILDE
                     DYKDIYALISKKNMALVKVKRWIDDDKASQIRDAKLSGIWVAEDNQRYYPYGNFAPYV
                     LGHTSSDATGISGVEMQYDKKLKGKPGKLIVSTDASGREIPQGMEKYYEPVQGNGLVL
                     SIDEVIQHYTEKAVQKAYELNNAKKVTAIAMNPKTGDILALASKPDYDPNDSRTPIYP
                     YYQEELEKYNDKDKIKGYYQMWRNPAVSDTYEPGSTFKLITSSSALEEGVIKDGEKFT
                     CTGSVTVGGRKIKCWRHYRPHGTQEFKQAVQNSCNPVFVELGSRLGVGKMYDYIESFG
                     LMDKTGIDLPGEAKGILYNEKNVGPVELATISFGQSISVTPIQLITAISSIANGGDLM
                     QPRVVKSYTDNKGNITETVKPKKVRSVISKETSKKMLEIAESVVTEGGGKIAYIPGYR
                     LGGKTGTAQKVIDGKYAPGKYICSFVGIAPCDDPQIVVLAIVDEPTGVSAFGSTTAGP
                     IVKEIMNDSLKYLGVKPVYKEEEKAEYEKKQVKVPDVRNLKIGDAVKALEDAKLKPDL
                     DADIELPEDTKVKDIFPKPGVKVNEDSSITLYFEN"
     gene            complement(51915..52262)
                     /locus_tag="KRH23_001623"
     CDS             complement(51915..52262)
                     /locus_tag="KRH23_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224904.1"
                     /translation="MKKNYKIHNLNEYKNKKKNNYKKRNKKKIGAKCILLIATFSVII
                     LNLCGYSKISEMKYDIYYLQKDLRKKEIVLEELKAKETEKTSIKEIELKAKELLNMDY
                     PKDGQIKYIDVDN"
     gene            complement(52743..53678)
                     /gene="rsmH"
                     /locus_tag="KRH23_001624"
     CDS             complement(52743..53678)
                     /gene="rsmH"
                     /locus_tag="KRH23_001624"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016434 - rRNA (cytosine)
                     methyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HHS5224905.1"
                     /translation="MEFHHVSVLLNECIENLNIKPDGVYVDCTMGGAGHSKEIVKKLS
                     DKGLFIGFDQDKNAISTAKERLSEYESRVKFVHSNFENIKEELEKIGVYKIDGVLADL
                     GVSSHQLDEADRGFSYMQDAPLDMRMDVRCEFSAYDVVNTYTEDELTKIIKDYGEDNW
                     AKRIAKFIVEERANKPIETTGELVDVIKKAIPKKARIDGPHPAKRTFQAIRIEVNNEL
                     GVITKMINDASSIMNEGGRICIITFHSLEDRIVKNAFKHLASDCICPQHLPICQCDKE
                     SEVKIITRKPILPSEEEIEVNPRSRSAKLRVAEKI"
     gene            complement(53708..54454)
                     /gene="lgt"
                     /locus_tag="KRH23_001625"
     CDS             complement(53708..54454)
                     /gene="lgt"
                     /locus_tag="KRH23_001625"
                     /EC_number="2.5.1.145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008961 -
                     phosphatidylglycerol-prolipoprotein diacylglyceryl
                     transferase activity [Evidence IEA];
                     GO_process: GO:0009249 - protein lipoylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HHS5224906.1"
                     /translation="MDRVAFTLFGIDIMWYGILMACGMILGTLIAIKEAKRVGIKEDD
                     VLNIAIIAIPVGLICARIYYVVFNWSYYAQNMSQIFNFRGGGLAIHGGLIGGILAGYI
                     YTKIKNINFLKMADTVILGMPLAQAIGRWGNFINGEAHGGATNLPWGIMVDGVKVHPT
                     FLYESIWDFGIFIVLLLFRKNKKYEGQVIVTYITLYSIGRFFIEGLRTDSLMLGPLRM
                     AQVISLIGVIGGIIAHVYLSKKNKNNISEE"
     gene            complement(54848..56134)
                     /gene="yfmH"
                     /locus_tag="KRH23_001626"
     CDS             complement(54848..56134)
                     /gene="yfmH"
                     /locus_tag="KRH23_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EF-P 5-aminopentanol modification-associated
                     protein YfmH"
                     /protein_id="HHS5224907.1"
                     /translation="MEKIVNDILKEEVYYEKLQNGLDVYFMPKRGFMKKYAILATNYG
                     SNDLEFVPIGEDKKIRVNEGIAHFLEHKMFEQPDGGDAFDKFSKLGVNANAFTNFTMT
                     AYLFSATENFYESLEHLIDYVQTPYFTDENVEKEKGIIAQEIKMYNDDPDWNVYFNCL
                     KAMYVNYPARIDIAGTVDSIYKITKEELYKCYNTFYNPGNMALFVVGDLDVEKVIDVT
                     KKSNNYKVDRLSKSIERFYPEEPESVKEKEVIEKFPISMPMFNIGFKDSNVGLKGKEL
                     LRKEIVTDILVGMLFKKGSKLYEDLYMQGLINENFGAGFSSQVDYAFSIIAGDSKEPK
                     KVKEIILDYIEKSKKEGLSKEEFERTKKKKIGSFIKCFDSINFIGNSFISYVFKDINL
                     LDYLDVIKDITFEEVEERLKEHFKEEYCVISIVEPK"
     gene            complement(56149..57414)
                     /gene="yfmF"
                     /locus_tag="KRH23_001627"
     CDS             complement(56149..57414)
                     /gene="yfmF"
                     /locus_tag="KRH23_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EF-P 5-aminopentanol modification-associated
                     protein YfmF"
                     /protein_id="HHS5224908.1"
                     /translation="MVNTKKIINLGNNINLTLIKTEKFKSNLISLYVQRLLDEKETTK
                     NALIPSIIASGSAKYPSARAISNKLDDLYGSSMGADAVKRGERQVLSFKVINISEKYL
                     DESIFEEVVEFFNEVINNTLVVDGGFKEEYLNIEKENLREKIQSIINDKKEYAQDKCI
                     EAMCKGERYSVSEFGYEDEIDSITSRELYEHYKNILKTSPIDIVVEGNFDEDKVVDII
                     SKNLKFEREEIINIPRADFIKNVDEVKVIDEQMEITQGKLVMGYRANVDYADIDKYYA
                     LVVGSNVLGGGPHSKLFVNVREKESLCYYIFSSIEKYKSIMFISSGIETKDYDKAVEL
                     IKKQVESVKAGDISDEELENSKLALVNSMKSITDNIGGMSDFVFSQSMAKTNSEVQDI
                     ISSIEKVTKKDIVEAIKNIELDTVYFLRN"
     gene            57730..58827
                     /gene="ychF"
                     /locus_tag="KRH23_001628"
     CDS             57730..58827
                     /gene="ychF"
                     /locus_tag="KRH23_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HHS5224909.1"
                     /translation="MKLGIVGLPNVGKSTLFNAITQAGAESANYPFCTIDPNVGVVSV
                     PDERLNKLQELYNSEKIVPTAIEFCDIAGLVRGASKGEGLGNKFLSHIREVDAIVHVV
                     RCFEDENVVHVDGSVDPLRDIETINLELIFSDIEILERRINKTQKAAKADKTLGSELD
                     LLKSIMSTLEESKCVRTMEFTEDEQTFVNSLDLLTSKPVIYASNVSEDDLADNGENNK
                     YVQQVKAFAETEDAEVVVVCAQIEAEISELDSAEEKKEFLETLGLEQSGLDKLIKSSY
                     ALLGLISFLTAGPKEVRAWTIKVGSKAPQAGGKIHSDIERGFIRAETIAFNDLVEHGT
                     MAAAKEKGLVKLEGKEYIVKDGDVILFRFNV"
BASE COUNT        18447 a        10657 c         6339 g        23424 t
ORIGIN      
        1 aatttattac ttttatagaa ttttcacaat aaaaagtcat tttacttccg tatttaatgc
       61 aaaagtagag attaaattta atataaaaaa tatataacaa atttttttta tatttctaga
      121 agaaaagtat actctttttt gtttaataat gctaaaattg atttgtattg aattttgatt
      181 aggaggaaat tattatgaaa gctcaaagat taaatgctgt acttgaacaa atgaaaaaag
      241 atgatatttc tcaaatgtta gtaagtgacc ctacttctat attttatctt acaggagtac
      301 taatccatcc aggcgaaaga ctattagcat tatacttaaa tttaaatggc aataataaat
      361 tatttataaa tgaattattc ccagtttcag aagatttagg tgttgaaatg gtttggttta
      421 atgatactca aaatccagta gaaataataa ctgaacatat agacaaaaat gctactatgg
      481 gtgttgataa aaactggcca gctagattct tattaaactt aatagaatta ggtggaggaa
      541 gtaagtttgt aaattcatct tatataatag atactttaag aatgtgtaaa gatgaagaag
      601 aaaaagagtt aatgagaata gcttcaaaat taaatgacaa ggctatggaa caacttaaag
      661 ctactgtttc tggtgaactt acagaaaaac aacttgttgg taaattatct aaaatatatg
      721 aagacctagg tactgatgga ttttcatttg accctattat aggttttgga cctaatggag
      781 ctaatccaca tggtgaacct ggaaatgcac ttgtgaaacc aggagatgca ataatcttag
      841 atataggttg tataaaagat aactattgtg ctgatatgac aagaactgta ttctataaag
      901 aaatacctga aaaaggtaga gaaatatttg aaatagttct tgaagctaat aagagagctg
      961 aagctattgt aaaaccaggt gttagattct gtgatataga tgctgctgct cgtaactaca
     1021 taactgaaaa gggatatgga cagtacttca ctcatagaac tggtcactct ataggacttg
     1081 aagttcatga taaaggagat gtatcttcta taaatacaga tactgtacaa ccaggaatga
     1141 tattctctat agagccaggt atatatttac caggtgagtt cggagttaga atagaagatt
     1201 tagtacttgt tactgaagat ggttgtgaga tattaaacaa acatgacaaa gaaatatgtg
     1261 tagttggtta attctaaaat caatttgata aaattaaaaa gccatataaa aatgttttaa
     1321 acatttttat atggctttaa tttctcaatc tatgatttat ttcaatccat tatttatatt
     1381 gcagtattta tattgcagtt attaagattg caccctttga agtatatgtc cccatcactg
     1441 aaccaatttc acagattaca acatctttgt attttacatc cttttccata acttccctta
     1501 ccttttgagc cttttctggg caattagcat gtcctataaa taaaaccttt tcttctttat
     1561 ctttaatttt tgactctact aaagtaatca gctttttcaa actgtttcct tcacctcttg
     1621 ccttatctat aggagttaca acgccatctg caacttgtat tatcgcctta aaatttaagg
     1681 tatttataat ttttcctgct attggattta ttctaccacc cttaatagca ttttctaaag
     1741 tttcaagtgt tccaaaaaat ggaggattat ctttatattt atttattatt gaaacaatct
     1801 cttcaatttc ttttccttct tttattaata ttgctgcttt taacactaat tgtcctattc
     1861 caattgaccc actaagtgaa tctataacct caactttctt gttatttcct tccttttcaa
     1921 acatatcttt tgctaaaagt gcactattat aagtcccaga taatcctgaa cttatattaa
     1981 tcactaatac actttcttcc tgacaatggt atgcttctaa aaatttatca ggagaaggac
     2041 atgatgtttt tggtagtact ttactctcac tcatttttct atagaaagtt tcattatcta
     2101 tttcctttcc agatatataa ctttcttctc caaaagatac atttaaacca acaacttcta
     2161 tgttgtattt ttctattata tcatcaggta agtcacatgc actgtccact atcaatttta
     2221 ttttatccat attaacctca ctataagata ttattttatt tattcagtcg gtcgtacgac
     2281 cgatttaatt attattttat atattgaatg aaaaaaagtc aatagatata gattctcgct
     2341 ttattgacaa taaatatcca taagcttata atgttattaa tttgttataa atatacatgg
     2401 aaaggtaggt tttatgaaaa caaataatat gaaacaggct attttatcat ctgcaaccaa
     2461 tttaatagcc aaaaatggag ttcaaaatac tagccttgct gatattgcaa aagatgtaaa
     2521 tataagtaaa ggtactttgt attatcacta cgcatctaaa gatgatatta tatatgatat
     2581 tgcggatact catttagaag ttataactag tgctatacta aactgtgtaa aaaatgtcaa
     2641 atcaaaaaat tctcaaatag aaatggttaa cttaatctta gagaaaatat ctactataga
     2701 aagtcgtggt agggtacata tgtatcttat ttgtgaggca attacttcaa ataatgattt
     2761 aaaggaaaga ataagattaa aatatattga atggagaact actcttaaat ctgaaattgt
     2821 tgaatcacta gaaaaatata atagtagcga aaatgaacag gatgctgaat cattttcttt
     2881 tttactcatg tcaatagttg atggtttagt tgtccaaagt ttattaaaaa cagaaaaaat
     2941 accttatgaa aatatagctt cttttttagt taatcattgg atttaaactt aatacttaga
     3001 taattaataa aagtgaacta tttaagttat ctactttaac agttcacttt cttatttatt
     3061 ctcaataatt tttacttaaa acattcaatt tttatttaaa ccttcatgga atcacaaaat
     3121 aaaaatctct tataaattta aaatgttttt atttatgttc atgtgtatgc ccatctgaat
     3181 gttcatgacc atgtgtatgt gtatgctcat ggctatgttc atgagtacct gaaaaaccat
     3241 catcatgatt atggtcgtga cctacaccat ttacatgctc atgttcatgc ccatgactgt
     3301 gagaatgttg atgtgaatgt tcatggttat ctcctccaca gcatccttct cctccagtcc
     3361 cacaacaccc acttgtatgt ggattatgat gatttcttac tacaaatctc tctcttaaca
     3421 taattcttat acctcctagt atattattga gtacttcatg taccccatta actacagtat
     3481 acatctaact aggtataatc tcaatacata tggcattttt taacatatat aattaacata
     3541 tataatctta aagaaattta tccttaaaac ctccaccttt tacttcttca acgttattga
     3601 cagaaataaa agcttcacta tccatatcat aaattaaatc tttaaattta cctatttcat
     3661 ttgcagatat tatgcaataa atcatctttt tcttattttg tgtatatgca ccttctgcct
     3721 ccaaaaaagt gactcctcta cccattttat tcattatcac tttggatatt tcatcatatt
     3781 tatttgatat taaaagtata gatttttttc tatcaaagca atcttttcct atatccatag
     3841 taaaagaaat tatatacatt gtaattaaag tgtacatcac caatttagct ccaaataaaa
     3901 aagctcctgc acatactaca aaaaaattaa taaataaaaa tgtatttttc ataggtatat
     3961 catactttct tttcattatg gctgctatta tatcaagtcc tccagcagta gctcttgctt
     4021 taaaagttaa ccccatacct ataccagtta atgcaccacc ataaatacac tgtagcatag
     4081 tatcatctat tgggaaatat ttagcaatat cttgtgttag ccccagtgct agagaaaata
     4141 gtaacatatt gacaaaactt attagcaaaa atttattatc aaaatacttt ctagctataa
     4201 taaatattgg tatgttcatc aagaaacttg atattccctg atttatacca aataatttgt
     4261 ataatataac acaaattcca gctactcctc cacttaataa cttggctggt gctagatata
     4321 aatttattcc taaggttgat agaatcatac ccaatataat aagacaatat tgtaaaaata
     4381 tattattatc aatacttagc tttttacttt caccatacat caaaacgcac ccctttgcat
     4441 aataaataaa ccaccctgca taacacacga taaatttaca aataaattta tcagaagtag
     4501 tttcctaaaa atattattca tcctcactta aacgtttatt cattaatatt ctatcacatg
     4561 acataaataa tttatatgat ttatatagat ttatttattg taaattttgg aatattaaaa
     4621 cattttattg aatagataat tatattacat aaaaaatccc tatagaaatc tataaactaa
     4681 tttctatagg gattttggtt aactaactat tatttttatt tttttataac ttttatacct
     4741 gtcatatggt catttaagtt ttgttcctct aaagatttat catctactct gtttatttct
     4801 aaagctaaag tttcagactt gatatattca ttaaaatggt caacagcctt agcaatttca
     4861 tcatcaccac agtattctat tactatatta tctaatactt caaagttatt agattttctt
     4921 aattgctgta ctttagatat aaattctcta gcataacctt cattaatcaa ctcttcagtt
     4981 agcttagtat ctagtataac aaaaagattg ttttcaacag atacattaaa tccttcctta
     5041 gcagttatac ctattaatac taaatcctta ttaaattcaa aagcttcacc atctaaatca
     5101 actgttaaag tctcaccttt ttcaagttta ttagcagttt catgagcatt taatttactt
     5161 aatgctccaa cgaataagtt catcttagaa cctaataatg gccctgcttc cttaaagttt
     5221 ggttttaaac taaagttcat atactcatct aaatccttag caaatattac ctctttaaca
     5281 ttaagctctt cttttattaa atcaactaca tcacttattg tatcttcaaa cttaccatct
     5341 actaacactt tttgtaatgg ttgacgaact tttattcttt ctacttctct tgaagctcta
     5401 cctaaagtaa ctaagttttt agctaaatcc attttttctt ctaatttagt atctactaac
     5461 tcttcattac atttaggata ttcagctaaa tgaacagata cttctcctgt taagtttcta
     5521 tacatttctt ctgacatata tggtgcaaat ggagctatag ctctacaaag accatgtaac
     5581 aattcataag ttgtattgta cactgctttt ttatcttctg ttaattcagt tgcccagaat
     5641 cttcttcttg aacgtcttat ataccagtta gataaatcat catttataaa atcttgtatc
     5701 attcttaaag ttttatttaa ctcaaatata gctaaatttt cttctacatc tttcattaaa
     5761 ttattgaact tagataatat ccatctatca agttctggtc tatctttata ttctacaaaa
     5821 aattcagttg gatttatatc atctgtgttt gcatataaag taaagaagtt atatacattc
     5881 ttcatagtac ctataaattt actttggatt tcttttaatc catccatatc aaatttagtt
     5941 ggagtccatg gtggagaaac atatagtaaa taccatctta atgcatctgc tccatattgg
     6001 tcaaataatt ccattggatt tactgtattt cctcttgatt tactcatttt cttaccatct
     6061 ttatcaagta caaggtctgg aactaaaaca ctcttatatg gtgcttttcc taatacaaac
     6121 gttgatactg caagtaatga gtagaaccaa cctctagtct ggtctatacc ttctgatata
     6181 tagtcagctg ggaacaattg gtcaaagttt tccttatttt caaatggata gtggtgttga
     6241 gcaaatggca tagccccact atcaaaccaa cagtctataa cctctgttac tcttgtcatt
     6301 ggttttccac atttttcaca ttttaagtgt atatcatcta catatggtct atgaagttca
     6361 actgtttctg gatttacatc ttctatagct ttttcagcta attcagctct tgaaccaact
     6421 gaatctgtat gaccacattc acatctccat ataggaagtg gagttcccca atatctagtt
     6481 cttgatattg cccagtcatt tagattttct aaccagtttc caaatctctt ctctcctaca
     6541 aaacttggga accattttac accattatta ttttctatta atttatcttt aagtttagtc
     6601 atctctatat accagcttgg ttttgcatag tatactaatg gagtttgaca tctccagcag
     6661 tgtggataat tatgaactac tttttctttg ctatataatt tattttcaga agctagccat
     6721 tttattattt caacatctag cccatcttcc attacaaatc taccttccca aggagtagat
     6781 gtaaatttac cagtttcatc tactggttga ataactggta aatcatatct tttacctgtg
     6841 ttgtagtcat cttcaccaaa tgctggtgct gtatgaacta taccagttcc atcttcagta
     6901 gttacataat ctcctactgt aataaaaaat gcttttttgt caacttctac aaaaggcatt
     6961 aattgttcat attctaaacc ttctaggtct ttacctttca tttcttctaa aacttcataa
     7021 tcttcaccta gtactttatc agctaaaggt ttagatacat aatatacctc atcacctttt
     7081 ttaactttta aataatctac atcagcattt actgttaatg aaacatttga tggtaaagtc
     7141 catggagttg ttgtccatgc taagaagtat tcatcagcat cttttttctt aaatttagct
     7201 ataactgtat tagtttttac ttctttatat ccttgtgcaa cctcatgact agcaagacca
     7261 gttccacatc ttgggcaata aggaagtatt ttatgccctt catatatata tccttctttg
     7321 ttgaatttgt ttagtatcca ccatacagac tctatatagt tattatctaa agttatatat
     7381 ggattatcta aatcaacttc ataagccatt ctctcagtca ttattctcca ttgtttttca
     7441 aatgagaaaa ctgactctct acatttttgg ttaaattcag ctattccata ttcttctatt
     7501 tgttgcttac tagtaagtcc taactctttc tctacttgta tttcaactgg taatccatgt
     7561 gtatcccaac cagcttttct ctttacttga taaccagaca ttgttttata tctacaaact
     7621 gaatctttaa gcgttctaga taaaacatgg tgtactccag gatttccatt agctgttgga
     7681 ggtccttcat agaatacgaa acttgggtca tctttccctt tttctaaagt tttttcaagt
     7741 atatttatgt ctttccaata atcaaaaact tgtgcttctg cttgttttac agaactgtct
     7801 accaatggct taaatttcgc catgtaaatc accctttcct actaaatatt ataattccaa
     7861 aattttttat tctttcacat aaatttaaat actaaaaaac tcgccccctt taaaccaaag
     7921 ggacgagtta taaatcgcgt taccacccta attctatatg taaactaaat actagctaca
     7981 tataacactc taatagtata acggtactaa ccggcacagc ttagtagaat ttaatcgttc
     8041 agcctgcagc tcaagagtga tttttatctt tataaattca ttggttctca gcatacccaa
     8101 ttctctgtaa aattatctaa agataaatgt ctctatcaac gcttttaaaa atttatctgt
     8161 gtttatatga aattctataa caaataattt gaatagtcaa tatatttttg aaaaatataa
     8221 taatttctat ttttcttaca tttttatcct atttttaatc tttgttatag atttctcaaa
     8281 ctcacacaat tattctacat aaaaaataaa caaattacaa gcttattcta aagttgtagc
     8341 agcttcatca ttactataat tatacactgt tgttccttca aatgcgttta cacatttttc
     8401 atctacatca taaaaaatct catcaacact tcttatttca tcttctaaca gtgatttaaa
     8461 tttatttcta aatatcttaa attctttaac taaagcatca tactcttttc ttatctctat
     8521 aacacggtta ttagcttgtt ctataatttg tctagctttt aaatcagctt cttcaacaat
     8581 tatcttagcc tttttattag ccgcgctaca agtgtcttct gctgcacttt gagcagttat
     8641 taaagtagct tttagtgttt cttcaatatt ttcatacttg tttacttggt cttgatataa
     8701 ccctaatttt tctttaagag ctgtattttc cctacataga gattcataat cttccttgat
     8761 gatatctaaa aattcatcaa cctcttcatc tctataccct cttaaacctt ttttaaactc
     8821 tttattttct atctcaattg gagttagcat tacatttcct cccagctata atttaaatta
     8881 gtccttatac aattaatctt gcttgaactt ttatttttcc ttttttagta atatctccta
     8941 tttgtgttac cttagctctt cctttgcctc taatagaaat caaatcatca ttttttacta
     9001 ttttagaagt tgaagttatc ttttcataat tgacatggac tttttctcca tttatgtatt
     9061 ttgcactatc ttgtctagat atattgtaaa taccacttat cacacaatct aacctatctg
     9121 aagatactgt aaatgatact tctttatatt ttgaagaact attaacaata ttttctctgg
     9181 aaatttcctt tacaattaca ttatttcttg aaaccttttc taagtttaca attataaaat
     9241 cgcaaatatc actacttaca actacttgac aaaagctatc atgtataatt atatctccaa
     9301 ttttttctct ttttatacct agacccagta ttgaccctaa gtaatcttta tgagatatat
     9361 ttttaaattt gaaattccct tctatttgta aaaatctaag agtatcttct atatcttcat
     9421 attccatgta aaatggataa ataaatacag tgcttctttc agcttgttca taacctccat
     9481 ccacactgta ttttatttca tttgtagaat ttaatattgc tacagcattt ttcacttcat
     9541 atggattaag aaactccgta gacttaacat catagttttt tatacaacta ttagccttgt
     9601 ctatcacttt aaacatttta tttttcaagt ctatatcctt tatgtgattt gttagtttta
     9661 atttatccat cctatcacct tagaatataa ccaatactaa ttgtcttagg aacatcaata
     9721 atactattgc aattaaagga gaaaaatcta taggtccatt tgtatattta tacattatag
     9781 accttattgg cccttctatt ggctctgtaa gattttccaa aatatcaaaa attttacttt
     9841 gtcttccatt tggaaaccaa gtcatcaagc tttttataac tatcatccat gctattatat
     9901 ctaaaagata ataaagtgca attcttattg ttcccatata ttaaccgcct ttttactatt
     9961 tattttgcca agggaagaat gctttacttt ctaattcttt tttcatattt gcatctatat
    10021 ccacattatt aggagctagt ataaatattg atttagaaac cttttgtata cttccatcta
    10081 agacataaac tgccccattc ataaagttaa atatagattt acgaacttca gaattagtca
    10141 atccttccaa attcactata actgcccttc tttgttttag atggtctgct atagttgcag
    10201 cttcatcata aaccttaggt tcaactatta caactttcat ttggctagtt gtatgtaaat
    10261 ttacaatttt atttgctttt gcagtactaa agccactgtt catttcttct tcttgaacta
    10321 tatcgtccat gccactttca tattcatctt caatgtaatc ttcttcttca tcaactatcc
    10381 aattcttaaa tttagatatt attccatttg acattattaa cttcctcctt aaaatttatt
    10441 caaatttgag taattatttt ttattgtagt ttctttctcc aaagattgat gttccaactc
    10501 taacaatggt agccccttcc tctatagcaa tttcataatc gtgactcatt cccattgaca
    10561 aaacatccat ccctacatta tggatattta gttcttttat ttgttttgat aaatctttaa
    10621 gacctttaaa tacacctctt atctcatctt catcttctat aaaaggtgcc attgtcatta
    10681 gaccctttat ttttatattt ttatattttt ctgacacttc tttgacaaag tctacaactt
    10741 cttctctatc aagtccatgt ttagactctt ctttagatat attcacttgt actaagcaat
    10801 ctatttctct gtttatttgt tctgcacgtt tttgaatttc ttcgcataat gcaattctat
    10861 ctaaagagtg tatcatacaa actttatcga ttatgtactt aactttattg gtttgcaaag
    10921 ttcctatcag gtgccagttt aatttgtcac ctataatatc atactttcta gctaattctt
    10981 ggggtttatt ttcaccaaca gaagtgattc cttctctcat tgcctcatta actaagtcta
    11041 catcaacagt ctttgtgacc gccaaaaggg taatctcttt gctgtctcta tctacttttt
    11101 ttgcagcttt atcaattttg tttcttatct cagacaaatt atctttaata gaacccatta
    11161 ttatcaccta ctttatcctt atatttgtgt ttatactgtt aggtcttaaa attattttgt
    11221 catatagatt aacacttgta actccattta tgtcattttt ataataatcc acaaatacag
    11281 aagattcatt ctcataagtt attccttcta atatgacaaa ttttacactt tgtgattgtt
    11341 catcaattac atatacacca cgtttattgt cttttgtttt tatagaagtt ttaggtattt
    11401 ttaaacattc catctgatta tatattatat caaattcttc gacacttgta tcctgatttg
    11461 caacaatttg gttacttatt tttaatttta ccattatttt attattattt tcatatattt
    11521 tgtaaacttt tgcatctaat ttttgctcat gatattcaat tattacattt tgattttttt
    11581 caaagttatt agaatcttct ttactgatgt atgtagatag ataattactc tggtcattgg
    11641 catctttttc tatagtccct tttacatgaa tctttgcatc aactttttca ttttttaata
    11701 ccaacgtatc tacatttttg ctaattatca ttactaatat attaaatact aaatatataa
    11761 gaataccaag tatcactaat ctggtatatt ttaccttttt caaagactct ccccctataa
    11821 aattactttc attataagta cttcttctaa aaaatgttta ttcctttttt ataagctaat
    11881 attttacgtt ctaataatta ttttttccat attaaattta ttttttatca atcttcctat
    11941 acaagactgc attatttata tataattgta ttataaagta taagtttaat ttacatttta
    12001 tacgttaagc ttactttata tgtttttata gttattttta tttttagatg caatataaaa
    12061 ccaattaaga tttaaaataa cttttgttat gttgacattt atttaggtaa tcatttatga
    12121 atcaggataa cgttatcata acaaaagttt atgtcctaaa aaaaatacaa ggaggatttt
    12181 cttatgtcag aaattttatt aggaacaggt ttacttttat tggttctatg ttgtttcaca
    12241 atttttagtt acaaggcccc atatggtatg aaggctatgg gagctctagc aaacgctgca
    12301 tgtgctactt tcttagtaga ggcattcaac ctttctttac ttggtgatgt tttaggtatg
    12361 gaatttttta gaaatgttgg agctgctaat ggtagtcttg gtggagttgc tgctgctata
    12421 cttgtgcctt tagccttagg tgtatctcca gtttatgcag ttttaatagg attatcttgt
    12481 ttagattttt ctatattatc tggattcgtt gctggatact ttgtttcttt cttaattaag
    12541 tttatagaga aaaaagtgcc acctggagtg gatttagtgg ttgtaattct tctatgtgca
    12601 ccactatctc gtcttatagc atcaaatgta gacccattag ttaatagtac actactacaa
    12661 attggacaag ttttgataga agctaccaac attagcccta taataatggg aattatacta
    12721 ggaggtctaa taacagtagt tggaacgtct ccacttagtt caatggctct tacatctata
    12781 attggtctta ctggtcttcc tatggcaata ggagcattag gtgcttttgg ttcagctttt
    12841 atgaactcaa cactatttgc aaaattgaaa ttaggttcta aaaaagatat tatatctgtt
    12901 gctattgaac cattaaccca atcagacata atttcagcta atccaatacc tatatattct
    12961 actaatttct ttggaggagc cttttctggt atcattgtag ccttgatggg tcttgtaaac
    13021 atgacaccag gtacagctac acctgtggct ggttttgcta taatgtttgc ttataatcca
    13081 gttcaacaag ttcttataac agctggttta tgtgctttat tcaatgtaat tgcaggattt
    13141 ttaggttcaa aaatattcag tacctttaaa gttcttactg ctggtgaaat acgtggtact
    13201 gatgtagaag aagaaattgc ttaaaaaaca ataagattta taaatttata tctcaagtag
    13261 tagagtttta tattgtaggc aattttatta attgcaaacg ttttattttt tatttatgtt
    13321 tatgattatt atgtgtgttg aatatttaga taaattttta tttattattt ttatttagat
    13381 ttttgtttag ttttttattt ggttgatata ttaggaataa aaattagtat agtttattac
    13441 tagttagata gcataacttt ttagatacat aaaaaatttt atattaatta gatattatta
    13501 aaataaaagc gatacatgaa tttttaaatg tccatgtatc gctttatttt tgccataatc
    13561 ttaacaacta atttttaaag tttattatct taacaaagtt cattatttta tataatattt
    13621 aaatgcatag acttctttaa tttaaccatc taaatattta attaaatatt attatatgta
    13681 atataactaa tttttaaatg aatgtatagg agctggaatc cttcctcctc tttgagtaaa
    13741 taattcagat gaatttgtat ttataggcat tactggtgct cgtcctaaaa gtcctccaaa
    13801 ttctaccata tcacctacat cacatcctgg ggctggtata attctaacgg ctgtagtctt
    13861 attattaatc atacctattg ctgcctcatc agctatcatg gctccaagcg tacctgctgt
    13921 agtatttcct ggcacagcta tcatatcaag acctacagaa caaatagcag tcattgcttc
    13981 aagcttatct atacttaaag cacctttaat aacagcatca atcatacctg catcttcaga
    14041 tactggtata aacgctccac taagtcctcc aacatgtgaa catgccatta ctccaccttt
    14101 tttaacagca tcatttaaaa gtgctaatgc tgctgtagtc ccatgagtac caacaacttc
    14161 aagacccatt tcctctaata tatttgctac cgaatcacca atagcaggtg taggagctag
    14221 tgataagtct attatcccaa atggaacatc caatctacta gaagcttcct ttgccacaag
    14281 ttgtccaact cttgtaattt taaatgcagt ctttttaact gtttctgaaa caacatcaaa
    14341 aggctctccc tttactttct ctaaagctct cttaacaaca ccagggccac ttacaccaac
    14401 atttataatt ctatcagcct caccaacacc atggaaagct cctgccataa atggattatc
    14461 ttctactgca ttacaaaata ctactaattt tgcacaacca aaaccttttg catcttttgt
    14521 taattctgca gtttctttta tgatttctcc catttctttc actgcatcca tatttatacc
    14581 acatcttgta gaacctacat ttactgaagc acatacttta ttagtacttg ctagagcttt
    14641 tggaattgac ttaattagta tcttatcacc ttttgtatat cccttttgaa ctaatgctga
    14701 gaatccacca ataaaatcta tacctagatc ttctgcagcc ttatccaatg tctgtgcaaa
    14761 ctttacatag tcattttcat ctgttgcacc tgcaataatg gaaattggag ttactgatac
    14821 ccttttattt acaattggga taccaaattc acgctctata tcttttccaa ccttcaccaa
    14881 atctttagca gaactcataa tcttattgta tattttttct ctagctttat ctccatcagg
    14941 gtctatacaa tctaataaag aaatccccat agttatagtt cttatatcca actgttcttc
    15001 atctatcatc tttattgttt caagtatatt tcctacattc actattatca cctcccctta
    15061 ctgtctacta cagattatgc attgaattaa atatttcttc tcgctgaatt tttacatcca
    15121 ctgataattt cttacctctt tcaaccaagt cctcaaccgt tttctcaaaa gaatttaatg
    15181 atttctccaa atcaactatc ataatcatag taaaataatc ctgtaatatt ttttgtgata
    15241 tatctactat gttgatattt tgcttgtata attcatcact aattcctgcc actatacctg
    15301 gtttatcctt tccaattact gttaaaattg ctttcataat aatatcctcc cttatttttt
    15361 tataaatctt atatttttac aaattgaact atgtgttaac atatatttca tttatttgtt
    15421 agtaaaccac tttttatgta tatatttaat atattttaat acctatacat tcatttgtca
    15481 attttttttc aatattctat tatttttata ctatttagaa aattcatata ttatatatgt
    15541 tttctcaaca ataaatacag ttttcataat aatgaaaggt attacttagc aatctcatga
    15601 ttttctaaat aatacctttc taaaaattat ttttttaatt ttatgaattt aattatactt
    15661 tttctagtat caggatttac aattaatata gaaccaatca taattggtgt tagtatacaa
    15721 aataaaaaaa taatatcttt ttttagatta tattctttag attctaattt ataattatta
    15781 tttattattc catcataatc acttatattt gacttatttt tatttgtatc ttgatttttg
    15841 ttagaaatac tttccctata aggaaaagaa tgttcattgg taccaaatac tgattttgag
    15901 cttaaatcat aattatcatc attttctgta attgaatttt tattgtaaaa tcctttttct
    15961 ttatcagaat tattttcttt attaccatct ttaggtatat catgaggatt tttattttca
    16021 ttgctatcag tacttgattc tacatcatct ttaggagtat ttggttgttt ctcatcagaa
    16081 ttatcatttt cattattatt attttcatta ttattgtttt gattgttatt actatcatta
    16141 ttttcatttc cattattccc atcttgattg ttatcatcct catctctatc cgggtcgtct
    16201 ctacctcctc ctccacggtc accatcaata tcatcatttt cccgttcatc atctggtgtc
    16261 tcttggttgt ctccgcctcc cattataaat cctggtttaa aaactatatt tgaataccct
    16321 tcttttaatc ctcctacaac ttttactcta aaacaacgca acttaaaatc ttcaaaaaaa
    16381 agtatagctt gatctctaat atcctcctgt tcttcagata tccaattgat tccatcgctt
    16441 gaatattcaa caaaaacctt acttgcacta tacggcatat cataaaataa aacagctaca
    16501 tatccatttt ttgtattttg aaattccagt tccaaattgt ctattggttt tttatctata
    16561 acagatacat tcaaaatagg aactacatca tcatttatta taattttttc tttatttaac
    16621 atttctgttt taaactttcc tgttatatta aaattttctc ccttttccaa cttttcataa
    16681 taatcagtaa aatcccattc tacatctata tcaagtcgat taccactaga tgtttctaat
    16741 accatatatt tgggaaattt tatattttct attttatcat ctttacttac ttttatttca
    16801 tcactaaata caccaattcc cctatgacaa catttcacaa tattgtagcc agaatcttca
    16861 gctatagaag gtataagctc attataatca tcaattatat aaactttctt actttctgat
    16921 ataattgatt gtgccaactt attattatct tttagtaacc cactttcatt gttgctacta
    16981 tatgctttta ttgaagtttc ttctatctca acatcacctt tagaataaac acctatagca
    17041 tgttctccat tcacttcaat atccttattt agtattctaa tatcattttc agtataaatt
    17101 cctattgcat cttttccatt tgcctttatt ttttcaacag attcgtagga tgatttaata
    17161 tgtaagtctc ctccttcttc aacgtataag gctgtcccat cagtagcaat tatgttgttt
    17221 ataccaatac ttatacttcc accattttct atatgtatta ctccttcttt tcctccttca
    17281 cctattatat tcaattcatt atcatcaata ataaatctcc catgattttt tatcaatatt
    17341 ttatatttgt tggtatctat tgtaaaatta ctgtcataag gaatataaaa tctaaactct
    17401 tcatctatta ccatatcaca agaaagagta taaactattt cttctttatt atttttattt
    17461 tcttgaaccc acctttcaaa atcttcaaga caattttcct cttgtccaaa aactttatgt
    17521 ggaaaactta taaaacacaa aactattata ctcataaaaa taaatatctc atactttttc
    17581 atcttacact cctagaaatt tttagctttg aaacaatcct gtcgaaacat atacttcacc
    17641 cactataatt tttccacaat tatcaattat tgtcaattta tataagtatc tttattaatt
    17701 gttataaata aaaagctact tactaaagca aacagacgtt tcactttaat aagtagctat
    17761 atttttataa caaaatagtt ataatattag aacttccttc atttacaatt ttttgtaaag
    17821 tcttttgcat tttaactctt atctcttctg gcatagtata taatttactt tgtaattgct
    17881 cttttactaa gtcatgtagt gacttaccaa acatatttga ttcccataaa tctgctggtt
    17941 gctcttcaaa tacttccata agatatttta tcatctcttc accttgattt tgatttccaa
    18001 ctattggaga aacctctgta gatatatctg cttttataat atgaagtgat ggtgcattgg
    18061 cttttaactt gataccatat tgttttcctt gtttcattat ttctggttct tccagactaa
    18121 gttcttctaa ggaaggagct actactccat atccttttat cttggcatct attaaagcac
    18181 tttctatttt atcatactca tttttaactt tagatagtct agttatcaga ctaagcagtt
    18241 gataatctcc ttcaatttta aatccacttt tttcttcaag gacattatag aataaatctt
    18301 gctttgtctg taaatcaata tttataacac cttctcctag ctctacatta tcaacacctg
    18361 tatcttccaa aaactctaac tcagaaaatc cttgtataat accttctata tcccttattt
    18421 tacctatatc tataatactt tgttttaatg ttgttattat gctacttttt atccaatgat
    18481 ttctttcaag accttcaacc cattttggta agttgattct tatttctgta agtggaaaat
    18541 catataatac agcttccata acctcctcta tatcttcttc ttccatttca accacattca
    18601 ttggaagaac tggaacttca tacttttctt ccaattcact tctaagcata ctcgtttcct
    18661 cactttttgg acttaacgta tttaaaacca ctgcaaatgg ttttttaaga tttttcaatt
    18721 cttgtataac tctctcttct ggttctacat agctttttct gtcaattcca gtaactgaac
    18781 catctgtcaa gacaactatc cctattgtag aatggtcttt tataactttt ttagttccta
    18841 tctctgctgc cttttcaaat gtcatagctt cttgtgacca aggagtggat actaatcttt
    18901 gttttccacc ttcctcatgc cctaaagctc cttcaactat gtatccaaca caatctacca
    18961 ttcttacttt taaagatact gtgtctttta tttttatttc tacaccatct gctggtacaa
    19021 attttggttc tactgtcatt atcgttttac ctgaaccact ttggggtatc tcatctcttg
    19081 ttctatcctt tttaaattca ttgtctatat taggtataac caacttttcc ataaattttc
    19141 ttataaaagt tgattttcct gttcttacag gtccaactac tccaatatat atatccccct
    19201 gagtcctttt ggatatatct tcgtatatgt tattattcat attattcctc ctatacatct
    19261 aatcttatta aattatattt agagttaagg gttaatattc ttaaaataga aaaataaaga
    19321 ccagcaatat taatttaatt tgcatataga aatttgtaaa tttcaatgta aattaaatta
    19381 atattgctgg tccaaatagt agtgtattat attaactgac tttagtagta ttttcatttg
    19441 aattattatt catctcaata agttctttac gtctttcttt tgtcatgttc atccatataa
    19501 atgtaaacac caatccaatt atggctacta tagtaagaac tatgaagtag tacctatatc
    19561 cagttacacc cggaaatgca tccaatatct tccctgctgc taaaggacaa agtacttctg
    19621 gaagatatcc taatgtggca actattccta tagcagttcc tgatattgat aatgaataat
    19681 taccttcttc aagtaacgaa tagtgtaaac cttgaattgc atacatagat acatatatta
    19741 caacacatcc aatcaatagt atataaatca tagatgattt tgttggtgta aatattacac
    19801 ctaaaagacc tgcaatcata agtataaatc cataagatat aatctttgat gaaccaactt
    19861 tatctccaag taatccagaa gcagctgatg ctactggtct acaatactga gctaatattg
    19921 agattgcaga tgcaaacacc acagtagctc caaatgcttc agttgaataa ggcgtaaaat
    19981 aataaaatga catattagct gaatatgaac aaaacattat tattgttatt atccatgtat
    20041 gaggcatttt tattactgca aaaaaggctt ctttatcaaa ttttgctgat acctcttttt
    20101 cattatcctt taatttgaaa aatactaata ctccaactat tacatttatt gccgagtata
    20161 atactataat agctgtaaga ccagatttat cacttacttt tgatgaaata tacccaaata
    20221 gtatcaatac tagagataga tgaattgcat tggtaattcc acgaccactt tccataaatc
    20281 caaaagcttt tccttgttca ttttcagatg ctaacattct aacagctttt acaagagctg
    20341 gccaaaaagt aagtattgtt gttattcccc ataaggcatg gattaaaaac acaacaatat
    20401 atggaggata aagtgttaat acaagaccag atattcctgt aataattaaa gaacctgaaa
    20461 gcaattttct ggctgaaata cggtctgcta aaaaaccacc aaaaaggtat gataccattg
    20521 caagtagacc ataaatgctt cctaagcttc ccatttgtgt atttgtaaga ttaaatgctt
    20581 gtgcaaaagt atcataataa taattcttta aatatggtaa agcatatata aatgctcctg
    20641 ctacaaagag tattatcaag actttgaaat ttttccaaat gcttggttta tttacttcaa
    20701 ctgacatact tcctccttat gtaaatacct gtaaattttc atgataatta attattgctt
    20761 attgtattgt ttattcaata tttcggaata tttattaata tattaggtta atctatcaat
    20821 aatttatggt gagttatgag ctaaaagtaa actcttttag ctcaccataa taattatatt
    20881 tttatttata ctaacgtcca gagttattag atatcttttt ttcatagttc ttccatagca
    20941 ttaaacctgt tattataaca aaaagacctc ctcctatcat ttcaatctca tagattatat
    21001 tatcttttaa agtctccata actggtgccg ttgagaaaag tatgccaact acagttacta
    21061 caagtaccat tctggcaata ttgatacaaa ctgaatcact ttttgcaatt gaatatggtc
    21121 tttcttcatt tggtcttgtc tttctaagtc taatataaga tgtaaaaagc aagacatatg
    21181 gaaataatgc tgttaatgct gtcatagtaa caagaacatt atatatatta tctactgatg
    21241 gtaataagtt tgttcctaca agaagtagac tcactattat agcctgaact attactgcat
    21301 ttgatggtat attgtattta tttgtaacag tcaattgctt aggaaataca ccttctctta
    21361 catttccaaa aagcatcttt actggacctg ctatataaag tattaatgct cctagtactg
    21421 ataaagttat tccaaatgct actattctta taaaccaact tcctatacct aaatcttgtg
    21481 caactttagc taatgcatct agtatccctg tagatgctgc aattttatct ggaggaagta
    21541 tcattgttat tgctactgaa cctaagatat agattcctcc tattaaaaca gccacagtta
    21601 atatagcttt aggaaagttt ttcttagcat tatccatttc ggttatgaaa ttagcagtcg
    21661 tttcagctcc tgataatgca aatattatag cagatataga aactaatgaa ttggcatcta
    21721 tttttggtat tatattttgg attgtatata tcgatgctga tggagctttt ttgagaataa
    21781 ctacagacat aaatgccatc actataagta atatagcagg aattgtagaa cctaatgctc
    21841 ctgtattcgt aaaaaatttt ccaaatgcca tcccacgagt acttactaag gacaacagcc
    21901 aaaatattat gagtgaaagt gctaaaataa acatcttatt gtttgataaa tctggatttc
    21961 caagcatata tgcaatattt atagctaaaa aagtcaagaa agaagaatac caaaatatct
    22021 ttgatgtcca atttagccat gacaccataa atccccactt ctctccataa gcttgtttaa
    22081 cccattctcc aagtccacca tcttttggat atgttgcagc caactctgca catataagtg
    22141 atgcaggaac aaagaatata aaagcaaaca ataaccaaac tggtatagaa ccaagaccca
    22201 atccaaaact agaggcagta gatttagcta tccatctaat cccaaatagt gctgatatat
    22261 tcataaatac taaatcccaa aatccaattt tctttttcac tgtaattcct ccaatttcaa
    22321 atttattcag actcatacac aatgtattga cttaaatatc aagtataagt tcttcaacac
    22381 ttcttggata attagttata attgtagcac cattcttacc tactattgct gtatctgagt
    22441 gtctaaatcc tccaactcca ggtatatata tccctggctc catagaaaat accattcctt
    22501 cttctaatat taattcattg tcaaatctta aatatggctc ttcatgttct gataaaccta
    22561 aaccatgacc aattctatga tttgaatata actctagacc atactttgca acaacagctc
    22621 ttgctgcttc atccaccatt cttgctggta taccagcttt tattgtatct aatccagctt
    22681 gttgagcctc tactgcaatc ttaaacactt ctttttgtct ttctgttggt ttgcctataa
    22741 taaaagttct ttcattttct gctctatagt tttcatacca aacctgtcta ctatgtatta
    22801 ctatatctcc tctttgaagt attctagtat tagaatctaa atgaggttgt gctgttctat
    22861 caatccctga acaagtccag tttgcaaatc ctatatatgt atcaggataa ttttcagaaa
    22921 catattttag taaagcatta tcccctgcaa cgtcaaactc caattcactc atcccaactc
    22981 taacattttc taaagaccct tttattccta tatcagatag gtaacctgct atcttcaaaa
    23041 attctatttc ttttgcatct tttacatatc tcatttcaaa tattttactt ccaacatctt
    23101 tgatagcaaa tgacttatca gttatatact ctgaaaagct tgcagatact atatcttttt
    23161 ctattccaac agttgttcct ttagggtatt tatttaaaat tatatctaag taatgtttat
    23221 gtgatattcc atgttctttc atttctggta tttcataata cacatataca ttatcaactt
    23281 ttgcaacttc tttagcatgt aattcttcta atccaggtac tattaattct attttatctt
    23341 gagttactac tgttacaatt ggtctagaat aagttattgc tttaaatcca ctaatataaa
    23401 attgattgtc tggttcaaat attaaagcaa tttcaatgct tttttcattc atgtactttc
    23461 tcaatctttc tagtctcata ttatttgaca taatgcacct ctttcttaat attcagataa
    23521 tttattcaat acaacaagga tgaatatatt attttaaaat tcttaatatt tttagtactt
    23581 gtcgtatttg tatgtaaatt aattttattt gtgattattt tatcataatc atgattattt
    23641 tgtcaatcat gattttattt taaaaaattt tttatattct agtgatttta aattatctaa
    23701 aatataacga gtatacattg tattttgtaa tattattctt gatttatggt aagtttaatg
    23761 ataaaatcac gattatataa actatattga ttatttgtag gtgaataaaa tgacaaataa
    23821 agaattacaa aagaaaagga tattgatgta tttcatagaa gctgctcaaa atattatgga
    23881 aaacgaaggt atagaaaata ttacacttcg taaggttgca gatatggctg gctataatag
    23941 ttcaactcta tataaatact ttaaaaattt agaccattta atatcatttg catctataaa
    24001 atattttaaa gattataact tgaatatttc aagatgtata gaaaatgtca atgatgaata
    24061 taagaaatat ataattatgt ggaaattatt ttgtaagcat tcttttgata atgctcaagc
    24121 tttttaccag gtatttttta acttgtctag tgatgaactt agctatataa caaaacaata
    24181 ttatgatatg tttccagaag atttaggtat tcatgatagt gacatatctt taatgattac
    24241 aggagaaagt ataaaggaaa gaaataagat actattaaac aatcttgtag atactggata
    24301 tataccagct aaagatttag acataatcaa tgatataatt atttcttttt atcaaaatct
    24361 attattctta aaaaagaaca caggaaaaaa ttctgatgat gatgaattaa ctatgaaaat
    24421 gatttcttct attgaataca taataaaaca tgctaaataa aattaaaata tggctgtctc
    24481 aaaatagaga taagcctttt ttattgttga aataataaaa atatatttaa tttcatataa
    24541 aaaagagtgc ctcgtaaact aaaaagttca ttttgagaca cccctaaaat aaatttatta
    24601 tttattatac aatagtttat atatcatcac ctaaaactac ttcttccatt tcatgctttt
    24661 tacttctcat cattagttct attccaactt ctttaggatt tgaacctttc tttattacag
    24721 aatatatagc attagttata ggcatatcta tatctaattt ttcagcaaca tcatgtgcta
    24781 cttcagtagc agttatgcct tctacaacca tctttacttc ttttaaagta tcttctaaac
    24841 tcatcccttt acctatgagt ataccagctc ttctatttct actatgcata cttgtacaag
    24901 taactattaa atctccaata cctgaaagac ctgcaaaggt agacatatta gctcccatag
    24961 caattccaag tctgctcatt tcactaatac ctcttgtcat aagggcagct tttgcattat
    25021 caccataccc taatccgtca catatcccag ctccaaatgc tataatattt tttaatgctc
    25081 ctccaagttc tactccaact atgtctggat tcgtataaac tctaagttta gggctcataa
    25141 ataaatcttg tatcatctgt gctattttta aatctttaga agcaactact acggtagtag
    25201 gaatatccct tgctacttct tcagcatgag atggcccaga tagtattaca tatggatttt
    25261 gtggtaattc ttcttcacag acttgagata atctaagccc agtccctttt tcaagacctt
    25321 tagctacatt aacaataact tgtccttctt ttataaatgg ttttattttt tggcaagtac
    25381 ttcttacagc ctgtgatgga actgctaaaa ctattacctt acaatctttt atagtttttt
    25441 ctatatcagt acttatagtt atattatttg gaaataatac tcctggtaaa tagtctgtat
    25501 tttctttagt tctgtttatt tttttagctt gttcctcttt tcgagtccac atgctcacat
    25561 cattaccttt ttttgcaagc cctaaagcta atgcacttcc ccagcttcca gtacctaata
    25621 cacatacttt ctccatgttt aacaccacct gagtataata tatttactat tctttctttt
    25681 gaccaatttt tctctctgtc ccatttaata atcgctttat atttgctctg tgattatata
    25741 ttactgatgc agttaagaac agagctacta ttaaaccagc tttatttttt accataatca
    25801 taaatattgg tgaacatcct attcctacaa cagaacccaa tgaaacatac tttgttatag
    25861 ctaccaccaa tataaatact gctagacaca ttagtgttat tactggattt acagctagca
    25921 ttgcccctag tgaagttgca acacctttgc ctcctctaaa tcctaaaacc gctggccaat
    25981 tatgacctgc tacaacacat ataactgcca gatatccagc taaaagagta tctattccaa
    26041 ccaatcttgc tgcaaattct gatattaaaa cagccattac acctttaaga acatcaccta
    26101 aaaatgtcat tgctcctgct ctttttccaa gtgtcctaag tacatttgtc gaacctgcat
    26161 taccagaacc ttgagtcctt atatcaaccc cagcaattcg ctttgcaact atgtatgagg
    26221 tagatatatt tcctaaaaga tatgcaacta cagcaataat tatataacta aatatctcca
    26281 ctgaatttcc cccctttagt tatattttaa gatatttatt ttttattttt ttgtctatac
    26341 tcaaacttta tggaagttcc ttcaaatcca aaattttctc ttatcttatt ctcaaggtat
    26401 ctttgatatg agaagtgagt taaatcctta tcatttataa acaatgtaat tttaggaggt
    26461 ctaatgtcag tttgagtccc atagtaaatt tttaatcttc tacctttgtc agatggtggt
    26521 tgatttaaca ttacagcttc tccaattact tcattcagtg ctgaagttga tattctctta
    26581 gaatgttcat ttgacacata ttcaactgta tctagtatct tgttcattct ttgattagtc
    26641 tttgcagaaa caaatacgat tggagcatac atcataaatg gaaatttttc ttttatatct
    26701 tttgtgtaat tgctcatagt cttattatct ttctctatta aatcccattt attgattaca
    26761 aatatgcatc cttttccttc atcatgtgct atacctgcaa cctttgtatc ttgttctgtt
    26821 acaccttcta aggcatctat tactatcaat actacatctg ctctatctac agcactcata
    26881 gctcttatta cactgtattt ttctattgtc tcatatattt tactttttct tctaagccct
    26941 gctgtatcta ttagaagaaa tttctgtcca tttttttcaa aataagtatc aattgcgtct
    27001 ctagtagttc ctgcaattgg acttacaatt actctttctt ctccaagtat cttattgagt
    27061 atagaacttt ttcctgcatt tggtttacct gttatagcta ctcttattat atcttcttca
    27121 tactctgtat ctaatcctgc tggaaaattt tcaactatct catctaataa atctccaaat
    27181 cccatactat tggctcctga aactgcaaaa ggcgttccaa atcccaactc ataaaaatcg
    27241 tatatgttat caaattgact ttgactatca atcttattaa ccactaagat tactggtttt
    27301 tttgtctttc taagcaattg tgcaatttct ttatcagcag ctgttattcc agctttacca
    27361 tcaactataa aaagtattac atgtgacatg tccattgcaa gcatggcttg atttctcatt
    27421 tgagataata ttatatcttc gctatcaggt tcaattcctc ctgtatccac taatgtaaaa
    27481 tatttatcta accattctac ttcagcaaat attctatctc ttgtaactcc aggtgtattt
    27541 tcaactattg atatcctttt tcctgcaaat ttattaaata ttgtagactt accaacgttt
    27601 ggtctcccaa ctacagctac aactggccta cttatactca ttttatttct ccttccatct
    27661 tttgttttct attttaaaat tttatccaca aaatcttttc cttcattcaa acaagggata
    27721 atttttattc tcataagttc ttctaattga tttaattcaa tattatctaa gaaaatttct
    27781 tcatctgctt ttagcatact tcttgttata taaagagctt ctcctaattc tttatcttca
    27841 agttgttctt ttaaatcctt agctgttaaa agacctgata cagttattgt ctctccaaaa
    27901 aacttgtttt tgatttcata tacatttact tgaagatttt taaacttgtc catcatagca
    27961 tctgccatac tctgtataaa ttcatatgca gaatgaccag tagctattga tactttcttc
    28021 tctcttttta gaatcttctc aggcaatata tttagatact cttcaatctc tgtttttaac
    28081 ttacgtatca tacctacacc atcttcaaac tgtaaaaaac cttcatattc ttcatatcca
    28141 ggcaattcac tattagatag tatataaaat tcatctgata aaaatgcaaa tcgagtacct
    28201 aatttttcaa gatatttctg ttgtatttga tgtatttgct ctatagtttt acttgcgctc
    28261 ttatcattaa atatatttaa ttctactaga ttttctctat gctttgtaat cccaactgga
    28321 actatcgcaa cactgtttac atacggataa agttgagcta gttcttttat tgttctatcc
    28381 aattcctttc catcatttat acctggacat aaaacaattt gacagttcat ttctatatga
    28441 gcatctgcca atctcttcat tataccatat aattttcctg caaatttatt gcttatcatt
    28501 ttttgtctta actctggatt agttgtatgc acagatatat ttataggact tattctatat
    28561 tttataatat tatttatatc ttcttcactc atatttgtaa gtgtgacaaa atttccttgt
    28621 aaaaaagata atctcgaatc atcatcttta aaataaagag tttctctcat accttctggc
    28681 aattggtcta taaaacaaaa catacactta tttctacagc ttttagcttg gtcaattatc
    28741 ggatttgtaa attcaacacc caaatcttca tcatagtctt tttctatctc gtatatgtag
    28801 acttcgccat cttttttttg tatttctaca tctaaatatt catcacttag taagaatcta
    28861 tactctatta tatcatgtat tggctgttca ttcacagata taagtaaatc tcctacctct
    28921 atacccattt cttctgcaat actatcttta taaaccttac ttataatatt atttactttt
    28981 tttacattta cttccaatat tttcaccact cttttgtatt catcaatgct tattataatg
    29041 tattttaata tgcaatttat ttatttatta tattttatga tagcattttt aagcatttca
    29101 tgtcataata acacatttta attctaatag tcaatataag taaatagcta taaaatagat
    29161 tagaacaaat aatattcaaa tttaagtttc ttaaaaattt aaatattatt tgttcttaaa
    29221 aaaattttat aaatttaatg ttttactatg attaacgtcc catttgtcat atcatgaacc
    29281 attccaccta cacactttga catcaacaat gccttatttt gtaagtcttt ctcatcattt
    29341 gcataaaata ttggacaacc accaccattt ttcatattct tatcaagtgt aactatagct
    29401 agggtatatt catttaaacc tatatccatt cccatcttat gcacttcctt tctttcctat
    29461 tttataattt tttagtgata agttttttcc tttagagctt gaaagtattg ggcatgactt
    29521 tacagcttcc attacttttt ccacattctt atctactggt aaataagcaa tcattatact
    29581 ttcatcctct ttatttcttc taggtaatgg tacgaatgaa ggttctccat aatctccata
    29641 taaacctaac cttgaatata tattgtatac tattgcttgt ctttgaccgg agtcaaataa
    29701 tattcctgca ttagcataat ccttattttt aggaattatt tgtattccta cacctctatt
    29761 aatatatact tctctatcgc tttttagacc tatatttgtt atacctttta aatctcccac
    29821 ctttagtata gattcgtcca caaaactaat ttcagcaggc attacatcag ctatgtctcc
    29881 aatacttttt ctagtaagaa gtttttttaa tataaaggct aacactaatc cacaaattga
    29941 acttattacc aaactcatcc cttcacttat tttcgtttct gcaagtatta cataatacaa
    30001 tcctattgtt aaaaaagatg taactataca catataattt cttacttcat aggttctagc
    30061 tatctcttct atgaatgcag ctcctctctt tacaagttga acttcctcta aattttgcaa
    30121 tgtatttctt ctatttgctc tcacttgtct aaattgttct gctgctagag ataaaaatgt
    30181 tatggatgta taagaacgat ttataagagc tggaaccaat aatgctccta atgaagaagc
    30241 gacgaatgct aatataagtt gagatagtaa aacatttggt tgcgttggat actgtttttg
    30301 gtctaaattc aacattataa ttctagatgt tataccaata ataacagcaa caaaaaatac
    30361 tctatccatt aaatcactcc taaaatattt aatttgaaat tttacatgta aatctacaaa
    30421 gtctttctag aaaaatcact ctgctttcct tttgatgttt ctatgatagg tgtacttttc
    30481 actacatcta tcatgacatc tatatctttg agtattggca tatatggtat aaccacagta
    30541 cttttttcta aattggtctt agatatagca acaatatcaa cctcatctac atctctatct
    30601 atccccatat gaataaatag attatgtatt atagcttgtc tttgccctat atcatttact
    30661 attccaaatg cacctaaatc tcttggtata acttctatag ccagacattc atttctatac
    30721 ttttctcttg tactttctag acctatgtta gttattatta caccatttac cattaaaata
    30781 ggtccttcaa aacttatttt tgcaggaact atatctgcta tatctgctat actgttcctt
    30841 cttaaaaatc ttctaaaaat caaaccaacg atagctcctg acacaatagc taagattgtg
    30901 caataaaaaa agctaaggcc atactttctt gcaaaaacga tataaactat cgaagatacc
    30961 agtgcagaaa aaagacttat ataacttcta gattcatacg tagatgctat ttcttcaacg
    31021 taagcgtctc cttttggtac taattcttca ttatcgatat tctttagtgt tattctttct
    31081 tgttctgcaa gaccttgaaa ctgttgtatt gctactgcaa aaaatgtcaa ggctgcaaac
    31141 tccttatcta taagtgcagg taatgctata gcacctaacg aagctgaaag cccagatata
    31201 attatctgtt ctaaataatc ttgtggtctt gatgggtatt gtttgtctgt aactcttaaa
    31261 actaatcctc tacataatat tcctacaact aatgcaacta taaaagagtg tctaaataaa
    31321 tttgcattca ataaactttc ttccattttc tcagctcctt ctcttatata gtttgtgcaa
    31381 aaaacaaaaa aaattccctt ctatttaagg aaattttttt gtaatattgt aactataaat
    31441 tcgctaccaa tgccaagttc actttttact tttatacatc catttagtga tttgactata
    31501 tgctttgtta tagccaatcc taaacccgtt cctcctacat ccctacttct tgctttatct
    31561 accctataaa atcgttcaaa tatgcgttct acatcttctt ttggtatccc tacaccattg
    31621 tctataactt taattacgat tttttcttca tcttttaaca ctacaacttg tacaatccca
    31681 ttatcttggg tatactttat agcattatca actaggttta agaacacttg ctttatatag
    31741 tctttattgg atagtatact tattgattta tcatcacatt tatataaaac ttctatattt
    31801 ttttcactag ctgaatgttg agttatttca tatacctctt taaatacatc atatactaca
    31861 acattttcca taagaagagt atctttattt tctacaaatg ataacaacaa tatatcatca
    31921 atcaaccttt ttaatctatc tgattcgctt tctattattt ctaagaatct atttctagta
    31981 ttcacatcta tattttcatt tgactttagt gtttcaacaa acccacttat agatgtaagt
    32041 ggtgttttaa gttcatgact tacatttgca acaaaatcac ttctcatatt ttcaagttta
    32101 acttttttag taatatcttc tatatttact atcgaaccta ttattacgtt gttagtattc
    32161 tgaagataaa ctgggtctac ttttatctta tatacgatat catctttagt agtaatatta
    32221 gcagtttcat tatctttaga accaataaat tgaagtattt gttttaatat ttcttcttct
    32281 tttattacaa cattaatatt atgaccttca actaattgat ttggttcact ctttatcatt
    32341 tcttttgctt catcatttat cagaagtata tttccattta catctatagc taaaattcca
    32401 tgagatatac tctttaatat agaccttaac tgtaaatgtt tatactgtac ttcttctaag
    32461 gttttatcca tattctttat catatgatta aaatttctag ctaattcgcc aagttctcct
    32521 ttggctgata tgttaagcct agcatgatat tcattattac ttactttttt tgagacgtat
    32581 ataaactctt ttaaatattt ccttaatgtt attgtgtatc ttacagctaa tataacaatg
    32641 gctatggaca acataacaat aaaaaaatat atactattta aatcttccac aagataacac
    32701 tcctaaaata taaccttttt aatctatttt gtatcctaca cctcttatag tctctatata
    32761 tttttccgat ttatcttcat cttctatttt ttttcttaaa tatcttatat gaacatctac
    32821 tgttctagtt tctccatagt attcataccc ccatatttta tccaaaagat aatttcttga
    32881 aagtactttt cctttatttt gaattaataa ttttaacaat tcaaattcct taagagttaa
    32941 ctctatcttt tcagagcctt tggtaacttc atgttttgat aaatctagtt ttaaattacc
    33001 tgtagtaagt atattgtttt cttcacctaa gctagtcaaa ttatatctcc ttaaaacaga
    33061 actaatccta gctaacaact cttttatact aaatggctta gttatatagt catcagcacc
    33121 tatttcaagc ccttcaacct tgtcattttc catattttta gcagtaagca ttataacagg
    33181 aatatttttt aagtccttat cacttcttat ttttctcaaa acttctattc cacttatatt
    33241 tggtaacatc caatctaaaa gtattaaatc tggtttaatt tccttagcct ttataaatcc
    33301 gtcaaatcca tcatatgaat aactaacttc gtaatttgac acctccaaat tgaattttaa
    33361 tagctcaact atatgcattt catcgtctat aacaagcact ttagtattca ttaaaaagct
    33421 cctctctatt ttatctgtag taccgttcct attcgttctg atgccttatt atgttttcta
    33481 taagagtgga atttatctgc tctacaacta gtgcataaat ttaaatttat tatattttct
    33541 tttttaactc cactacatct aagcatatac tcattaattt tccataaatc taaatagtaa
    33601 cttccctctt ttattatata gaacttttca tcattatttg taagaattgt gttaaatttt
    33661 tctactaaat cttcagacac ttcataacaa catggtccaa ttgatggccc aattatacat
    33721 actaaatctt catgaactgt tttatagcat tcagacatta attttattgt tttatgacct
    33781 atattactaa aagtccctct ccaacctgca tgagccagtc ctatggcttt atttttagca
    33841 tctataattg atataggtac acagtctgct gtaaacagta aaagtggtac tttttccaag
    33901 tttgttataa gtgcatctcc atctcttctt ttccctatag tatctttatt gactatatta
    33961 actatatctg aatgtatttg agaattacta gttagatttt caaatgtcaa atcacattct
    34021 ttacatactt ttaacatatc ttctctattt tttgcatcta tattcttaca tgttataact
    34081 agatttacag aatttaattt ttcatcaagt tcttcacaat tatcacttaa attaacatac
    34141 tctttaatat cttgtacatt ttttatattt atataatctt tcatcatttg tctccttttt
    34201 ctatcagtat acttttaagt tcatttacaa aagtatttat atctttaaat tgtctataca
    34261 cagaagcaaa tcttacatag gcaacctcat ctaactcttt caatttatcc attaccatct
    34321 caccgatttt tttggtttca atttcttcta taaaacattt atttatttca ttttcaatat
    34381 gtacaacaat actttcaatc tcgtcaatag aaacaggtct tttttcacat gcttttagca
    34441 atccatattt tatcttttct ctatcaaaat attctctact attatccttt ttaatgacca
    34501 ttaaaggagt tgtttctatt ttctcatacg tagtaaacct ctttttacat gattcacact
    34561 cacgtcttct tctgatagat tttaaatctg tatgtctaga atctattacc tttgattctt
    34621 tataattaca ataaggacat tgcatctata ttcctccttt gtttaactat atctcaaact
    34681 catctaagct taattctgaa cctatattta ctattattgt atcacaacct attttaagta
    34741 tatcattcca aaatataact tcttcatccc ctcctcttga aaaaaaactt ctacttccat
    34801 ctccaaaaat ggtaaatgag actaccttac cttcgtgaat atccatgtct atgtctatta
    34861 taaaccccat cctttttcca ttttttacat ttataatttc tttttccatt atatcagaaa
    34921 ctctaatcat attgtactca ccctttcttt aaaaataaat atgtatcgaa gtaaaaaaaa
    34981 atgacctata taggtcattt aaattaaaat aatgtttaca gtccatggat tacttataca
    35041 tattttctca tattctttaa agcatttttt tcaattcttg atacttgtgc ttgagatata
    35101 ccgatttcat cagcaacttc tatctgagtt cttcctttgt aaaaccttaa atctaatacc
    35161 aacttttctc tactatttaa tttcttaata gcttctttaa gtgatatttc ttgcaaccaa
    35221 ttttcatcag tatctttttt atcttgaacc tgatccataa cgaatattgc atctccattg
    35281 tcttgatata ctgggtcaaa cagagatatt gggtcttgta tggcatcaag tgccattaca
    35341 actgattcta cttctaattc taattccttt gctatttctg atactgtagg ttctttagaa
    35401 tttgttctaa ttaatctttc tctaacttgt agtgccttat atgctatatc ttttaatgac
    35461 ctacttactc taattgggtt attgtctctt agataccttc taatttctcc tataatcata
    35521 ggaacagcat aagttgaaaa ccttacattt tggcttaaat caaagttatc tatcgctttt
    35581 ataagaccaa tacaacctat ttgaaataaa tcgtctatat tttctcctct gttgttaaac
    35641 ttttttatta cactcaagac taatcttaaa ttccctctta caaactgttg tctggcttct
    35701 tcatcaccat tttttatttg taataaaagt tccttcattt gcttattttt aagaactgga
    35761 agttctgatg tattaacacc acatatttca accttattaa cttgcatata ttttcagtcc
    35821 tctctcaaaa gtattcatct attgaaatta tttacatttc caattttttt atacttttta
    35881 agaagaatta atttagcatt atacaaattt tttcatttct ttttgtaacc ttgagattat
    35941 tttcttttca agtctagata tgtaggactg tgatattcca agcattccag caacttcttt
    36001 ttgtgttttt tcaatacctt tatcaataag accaaatctt aattccataa tttgcttttc
    36061 tctgtcactt aatctgtcaa gtgccataac caacaaatct ctatctattt cttcttcaat
    36121 tattttgtat atttcatcat tttctgtacc caatacatca gataataaaa gttcatttcc
    36181 atctaaatct atatttaaag gttcatcaaa tgatacttct gttttctttt tattattttt
    36241 tcttaagtac attaatattt cattttctat acatctcgaa gcataagttg ccaattttat
    36301 atttttattc agtttaaaag tattaactgc ttttatcaaa cctatagttc ctattgaaat
    36361 caaatcttct acatctatac ctgtattttc aaattttctc gatatgtaga ctactaatct
    36421 aagatttctt tctattaaaa ttgactttac actttcatct gtttctagct tttgtaaaag
    36481 ctccatttct tcttctggtt tcaatggagg aggaagtata tttgcccctc ccatatagta
    36541 tattcccttt ggctttatta tttttaattt aatacctaac atagtaataa agcttattat
    36601 tctttctttc aatcgtaaca ttccttgtcc cccttaaatt ttcacctaaa atccaggcaa
    36661 tatatttgga ttcattattg ctccatattc tctatcatta aaatttgaaa taccaagtat
    36721 tatatttcct atcttttgct catctacttc tatatagtca gcttttaagc ctattattat
    36781 gcttgtctta ttacttccag catgtttata aggtattatt ctaactctac ctgaagtttt
    36841 atcatctaaa cttcctataa tttcttgtgc tttcttcata tctatatctt cataattaat
    36901 atttaatagt ttttctggaa taaatccttc taacacacta gacttaacta ttattacatc
    36961 actttgactt attgggtctt ttaacaaatt accactatct actaaagcct tacagcaaaa
    37021 acttttttct agtaagttta tatttatagt ctttgtaagc tccttaatgt acttaagcat
    37081 tttcaaatct ttataaatgt attttaataa ttcacaactc acataagtac atgcaattaa
    37141 gaaagatatt tttaagtgac ttattcctgt aaaataaatt ataaaataag tgcttccaga
    37201 aataaaaatg tttactagat aaaaaactaa cgctacatga acataatctt ttttgctctt
    37261 acttctaaat gaaattaaag ttattatact catgattatt attttaaatg gtacagtaaa
    37321 tagtatattc attgatggat acaaataagc aacagaatag gcacctccta aactagcccc
    37381 caataactta ttttttttag gattatatct tttagtaaga atagaagtac aacttataat
    37441 aatataattt attactaggt tttctataac atagtactca atatacacca tgtatccccc
    37501 cttaaaacct ttaaacatat tataagatag tatgtacaaa attttatgtc acttttgatg
    37561 gtcgaatcca aaacaaattc tatttaaaaa gaacaatgat atatgtctta tactttatgt
    37621 cgtcaaaaga tattttttta atgccaaaca aatagacttt tttgtagaat ccaatatatc
    37681 taggtagaag ttattcgctc tacttttggt atatttacaa aaaaagacta cataatttaa
    37741 taatatatca agtaaatctt ttacttatat aaaatcaaat tatatagtct gtaaattcaa
    37801 atataaatta ttgtgctagt aatccatttg catattttgc agattcattt agtgcttgtt
    37861 ctggagttat gtctccagct atcatcattt gaagttgttt ccataaatat tcatatatct
    37921 ctactccatg aggtccaact gtcaatggtc tatacatatg tttatctctt gtcaccattt
    37981 cttcaaatct tgggtctcct tggtattttt cacctttagc aactggagct ctaggtattt
    38041 ctttgtggaa agcttccatt gattctttgc ttagcatata ctcaagaagt ttaaatccaa
    38101 gttctttatt tttacatgct gacattaatg ttaaatcatc tactgaagca aaacttccaa
    38161 ctgtcttatc ttctaatgat gttacatatc cccagtttaa atccgggaat gatttatcaa
    38221 aagtacttgt agcagcagag gatagcatta tagtaaatgc agcttttcct ggtccaaata
    38281 cactttcaat catttcatta ctatcttttg ataaagcatc ttctggaata tactttttca
    38341 tatcatttat aaagtttgca gctttcaagc cttctgcatt attaaattta actgatttta
    38401 aatcatcatt atatatatct ccaccagctt gccataaata cggataccag ttccagttta
    38461 agcttccaaa tactttagaa ccccaacctt gtgcaagacc ccactggtcg atttttccat
    38521 ctccatcagt atcttttgtt gctttttcac agattctttt aaaatcatcc catgtttttg
    38581 gaggtttttc tcctaatttt tctagtatat ctttattgta gtacaatacg cctggattag
    38641 cagcttctat aggtaaacca taaataccac ccatcatttt tgcatcatct aagtatagat
    38701 aattatctga agttcctgat ttttctaaat aaggtgttaa atcttctacc gcacccattt
    38761 ctataaattg aggaaacatc tctgcataca tgtatcctat atctggacct tcacctgcac
    38821 ttattgctgt tgcatatttt tctgcgtagt tatcccatgg tactatctga aattcaattt
    38881 cacagttatt ttctttttca aatttttcaa atatcggctt ccatgcatct gcatcatggt
    38941 ctgttaatgg tgcagaccat acaactaatt tttctttacc ctctttgcct ttagaatctt
    39001 ctttttttga acatcctgca agaattgata ctgatagaat ccctaccata actaaagaaa
    39061 gaaccttttt tagtttaatc atgcttaatc ccctttcaga ctttaatttg tctttttcct
    39121 caaatgttta catttaattc agatttaata ttaacaaata agattactct tgtctaatca
    39181 taaaaaacta tactaactcc tataactata ttttttttct atacctatta gatttaattc
    39241 atactaaaaa cttacttttt aaattttatc aatatttaaa aatattttta agtctagcca
    39301 caaactaact atctaaattg aacaaaataa aaagaagtct attgacttct ttataagctt
    39361 acatattatc ttcttcttct taggaatgta ggtatctcca tgctctcatc atcatcttct
    39421 tcaattatac ttgccttttt aggaggctct attttttcct cagcaattac ttcttcttca
    39481 atttctttta cagcttgttt tactgttgta tttaatgaag aacgtatgct tgatttaggt
    39541 ttagtatcta aatctaaggc accattttgt aatccttcaa atcctgtcgc gattactgta
    39601 atcattattt catcacctaa atcttctttt atagaagctc caaatataac atttgcttct
    39661 gggtcacagg attccataac taaagttgat gcctcattaa cttcaaataa tcctaagtta
    39721 ggaccacctg taacattaag aagtactcct ttagctcctt gtattgatgt ttctagaagt
    39781 ggagattgaa tagcttgtct tgcagcatca attgctctag tttcaccact agcactacct
    39841 atacccatat gagcaagtcc cttgtctttc attatagtag taacatctgc aaagtccaag
    39901 tttattaacc cttcaactgc tataaggtct gaaattgatt gtataccttg ttttaataca
    39961 tcatctgcaa ctgcaaaagc atctaacatt gatgtatttt tttgtactat ctgtaaaagt
    40021 ctatcatttg gtatcgttat aagagtatct acttttgatt taagttctgc tattccacct
    40081 tcagcgttct tcattcttat cttaccttca aatgcaaaag gtttggtaac tacacctact
    40141 gtaagtatcc ccatttcttt tgccaagcct gcaaccactg gagcagctcc tgtaccagta
    40201 ccaccgccca ttccggctgt tacaaagacc atatcagctc cttgaagtaa ctttactatt
    40261 tcatctttac tctcctcagc agctcttttc cctacttctg gatttgctcc tgctccaagt
    40321 cctctagtta atttttctcc tatttgaact ttatattcag cttttgatgt atataaagct
    40381 tgtttatctg tatttactga tataaattca acgcctttta gttgagcttc taccattcta
    40441 ttgacagcat tgtttccacc gccacctaca cctattactt taatttgtgc acattcttct
    40501 aattctacgt caaagtttag catcataaac ccccttctct catgattcaa agttatcgta
    40561 tgtattaatt atatcatttt cttcttttat tttgttaacc tttaagtaac atattccaca
    40621 aaaacgtaaa ttttcctttt taaatttctt acttatattg tcaaatatta ctctttaagt
    40681 ataaaataat ttacgtatat attaaatgct ctttaatttt tacgtttttt gttcataata
    40741 ttactaataa tatatcgtct aattatagat aagttattaa acaatctcat accaaaaact
    40801 aatacagcaa catagtaaag agaaactcct aacttttctc ctatataagt caataatata
    40861 gccaatatag cattacctat gaaaccagta ataaaaatta cattatcata gttatcttca
    40921 aaattggatt ttatcgctcc aaaaatagaa tccattattg caagaatagc tactgacata
    40981 tatatggaat aatccataga atatgtaaat ggaatatagt aacctactac tacaccaaat
    41041 gctaatcctc ctaaaaccca taacataaat cttcacctct ttattttact ttgaaacaca
    41101 actacattac aatccttttt attaattttt tttacttttt ctttattttt ttgtattttt
    41161 cgttttattt tgcaaataaa ttcactttat ttccattatt ttcctgaact tttatattaa
    41221 ttccatatat atccttaaga gatttagcat atgattctgg agagtttata gctgcactca
    41281 ataaatctat atctcctata gcttttatta taaatggttg tccatatgta gtatcattta
    41341 ctgtaatagt agctcctgaa cattttatct tacttgttgc tagtactctt tctccattta
    41401 tagaaattgc tcttgctcca gcctttttta aatcatttaa aaccctcaaa atatctatat
    41461 catgtataat caaatcgttt ggattctgtc cgtcttttaa ctctctctca ctatccctca
    41521 tagtaatagt tatgcctggc cctgtaacag ttgaataacc acttaactct ttaacttctt
    41581 caagctcttt ttgcataagt gtttggatag attcatttcc attctttttt gcttctttat
    41641 attcattcaa agtttttttg ttctttttaa gagtttcttt taaatttttt atttcttttt
    41701 ttgtattttc tacctcactt tcaatacttt cagtttgacc taatgttatg tatactctat
    41761 ttgggtctag tgattttata taagttgata tgaaaacgcc taatatgaat gctcctaata
    41821 taactatttt ctttttcata ctattatttc ccctctgctt tgtttatatc actatgacca
    41881 tttatttcta tattgtcttc tttggtcact tttactttgg cattataata tgtttctatt
    41941 tcccagacaa taccatactt tatattaagt gctgaagcca atgtatcaga atcaccaatt
    42001 gcttttatta taattggttc ttttatgaca gtgtcattca tataaagctt gtcttctttt
    42061 aaatacatat atgtattaga aactattctc tggtcgttta tagatatggc acttgcttgt
    42121 gctgaattta atttatttat cattgataat aataaatcat aattatatag tatactatca
    42181 tttttatcag agtttcctaa gtcttttgta gaatttatct caatttttat gcctgttcct
    42241 tcaacatctg tatatccagc taatgtttca tatttttcta tttctgactt aagtatgtct
    42301 tgttctcctt cattgttttt gcctctataa gtctctatat ctttcttcac actattaact
    42361 tctgattgta gattctcttt ttcttttttt aatgatttaa gttcttctgt aagttgctct
    42421 cctcttttaa aagttgtcat ccctctattt tctatattaa taattttaag ttgtaaacta
    42481 acaagaacac ccaatacaat acttcctatg attatacttt tatttataaa tctttttttc
    42541 aatatatcac ttccttacaa ttgtctatcc ttctggacta tacactgcca actttccata
    42601 gttaagattt atagtccctc cattagtatt tttattttgc aggtcaatca gaattttact
    42661 taccctagat atattataat ctaagttatc atcattagaa agtaagattt ttatattact
    42721 tcttgtaagc atttctatat tgctttcttt ttttaagttt acataattta tttttctata
    42781 aattccttct tcttttaaat aatttaaagt tttaaataca ttctccttag ttttataatt
    42841 tttaaatttt atagatttat tatcatcaat gctataatct acatctacta tcaagtcttt
    42901 tttactttca ttagaacctc ttagttcttc caataaattt ccttttttat ctatataaca
    42961 ataattatct tcatctttta atactgcaaa tatttctttt tcttttaaac ttataattat
    43021 cttattggga agttttcttt ttatttccac attttctata tatggatttt ttataagttt
    43081 atttttcata tctttaaaat tgtatgcaaa aatattttca tttagattta catttagttc
    43141 tttcattata tttgatttgg tcaccctctt atttccaatt acatctattt tctttacatc
    43201 aaataaatca ctttttacaa ttatacatat acaaaaagat aacataagta taaaaactaa
    43261 aactatcatg acattattcg tatttaactt tcttcttttt ttcaaatata atcaacccct
    43321 ttggttaata aatacacctt tagagcttgt ttttcctaca aaaaaattat aatatttaaa
    43381 gtcaaatttt tgcattttat tacataacat ccaaataagg tattaaattt tataaataaa
    43441 tcaatatttc atcaaaataa acatagcata ctacatacta tttatatatt taaatctgta
    43501 tacatacaaa taaaccccta atttataata atttagaaaa tctaatatat tataaattag
    43561 gggtaaatat ttacttatct tttctttatt cctattacct tagcttgacc ttctatactt
    43621 ggagtcgttt ctttttttat ttcttttact tccttaataa ctttttcttt ttttgttttt
    43681 ttagaagttg acttttgtgt tgaattgtat actttcatta tctcatcata tataaggtct
    43741 atggcttcag gcttacctat agttttactt gcatttgcca tatcaaccaa aagttctcta
    43801 tctcctaaaa gtttaaatac tgctgtattt aggctctctg gagttagatt tttttctaaa
    43861 atagcaattc ctgccccttg tttttctata ctcttggcat tatactcttg atgattttca
    43921 gcagtataag ctttaggtat tattatagat ggctttccaa gagccgttat ctcagctaat
    43981 gaaattgctc ctgcgctacc tataaccaaa tcacttgctg caagtgcatt tgccatatct
    44041 tctaagtaag gcacaacttt ttggtatggt ttaagattta tatcgctaat acttcccata
    44101 aattcatcat aatagctttt gcctgtagca aatataaaag ctatatcttc atttaccata
    44161 ttctttatta caagtctcat tgcatcattt atttttcttg aacctccact accaccatag
    44221 caaagtacca ttcttttttc gtcacttatt gatagattct ttcttgcaat attttttctt
    44281 gataataaaa tttcttttct aactggattt cctgtaaaaa ctaatttatc ttctgctgcc
    44341 tctggaaatc ttttatgcga atcttcaaaa cttgtaagta cctttgtaac tgttttagat
    44401 aaaatcttat tagttacacc aggaaaagaa ttttgctcat gtattatggc tggtattttc
    44461 cccatagatg cattaaataa aacaggtcca ctaacatatc caccagttcc tataactata
    44521 tctggtttaa atttcttaac aatctttctt gattgctcca aacctttaaa aagcttaaaa
    44581 actcttttta cattatcgaa atctattttt cgcttaaaac cttgaactgt tacagtcttt
    44641 aattcaaatc catacttagg aactatttct gactctattc ccttttccgt cccaacaaaa
    44701 attatctcag cgtctggatg ctcatctctt attttgtttg caatagctat agctggatac
    44761 acgtgccctc cagttccacc gcctgataat aaaactttca tcaaatcatc atctcctgtt
    44821 aattaatttt gacatgcttt gagatgttta acactattcc tacagctccc ataaagatgg
    44881 tgagtgaagt tcctccataa cttataaatg gtagtgctac acctgtagct ggcattgatg
    44941 atgtcgcaac tgctatattt aaagctgctt gtattccaat ttgtgcacct atacctataa
    45001 caaccataca agcaaataca ttagaagtct tcaaagctat tcttacacat ctgtagacta
    45061 aaactacaaa tagcataata actattatac aaccaatcaa tcctaactct tctcctatta
    45121 tagcaaatat aaagtcattt tgtggctctg gtatataaaa atacttttgt ttactctttc
    45181 ctaagcctag accaaacaat ccacctgaac ctagtgcata tagaccttgt attacctgat
    45241 accccttacc aagagggtct tgaaaagggt ctaaaaatga tgtaacacga ctaagtctat
    45301 agggttcagc aattactaat gcagcaaata aagcagcccc actccctatc atagcaaata
    45361 caattttcat atccattcca gcaacaaata tcattacaaa agtaactaga attacagtac
    45421 ctgctgttga caaatttggc tgaagtatta tcaacgcaaa aaatatccct ggaactacga
    45481 gaagtggtac aacacctttt gtcaaagatt ttattttatc ataatttttt tcaattaatt
    45541 ttgcagttaa tattattgta gcaaactttg cgatttctgc aggttgaaat gttaaagctc
    45601 ctattcccaa ccatcttttt gctccgtttg cttctatccc taaaggggtc aaaactaaca
    45661 ataataatac tactgctata gctccaattg ctgtagcatt tttcttccaa aaactataat
    45721 ctattcttga tgtaataatc ataactataa atccaagtac agcatatatt acattctttt
    45781 ttagaaaata gtacgcatca ttgtgtttaa atgaagattg tataaaactt gcactaaaca
    45841 ccataactat tcctacaaat actaaaagca tagtagtgta aaacactact ccatcaaatt
    45901 cagtcttcat ccttatgtca atttgttttt tcaaattttc tttaggcatc caactaatct
    45961 acctccattc ttccatttaa gtaagtttag aggtaagaga ttattttaaa ttgtttacat
    46021 tatctttgaa gtcttttcct cttacttcaa aactttcata catatcccaa cttgcacaag
    46081 ctggtgaaag aagcactata tctccacttt ttgaaatttc ataagaagtc ttaactgctt
    46141 cttccatatc ttttactata tgtatgtcat taaatccttt atttttagca caattttcta
    46201 tatttgatgc agtttctcct aataagacca atgatttaac atatgacttt gcagtttcaa
    46261 gaagttcatc aaaattactt cccttatcca tcccccctgc tataagtatt ataggtctat
    46321 cataagactg tatagctttt atagtggaat ctggattagt tccctttgaa tcatttacat
    46381 atattacatt gtctaaattt cttacaaact cttgtctgtg ttccactcct ttaaatgtca
    46441 taagtacatc ctttataact tctaaatcaa ttttgcagac atatgctatt gctatagctg
    46501 ccatacaatt ttctaagtta tgacctccag gtaaacttac atcatcttta tttagaaatt
    46561 tgattttatc atctatatct attattatgt cattattttc taaatatact cctccattta
    46621 cttttttagt tcttgaaaag taaattactt tggcattgca tttatcagct aaagatttta
    46681 ctatctcatc atcatagttt aatacacaga aatcctcaac agtttggttc ataaatatat
    46741 ttgcctttgc ttctatgtat ttttccatag tatggtgtct atttaagtgg tcctctgtaa
    46801 tatttaatat tgcgcttact ttaggtctaa attcatctat actttcaagc tgaaaactgc
    46861 ttagttcagt tactaacaca gactcttcac ttgaagtttc tatagtatct attacaggat
    46921 ttcctatatt accaactaca tatgtatctc gttttgctct tgaaaaaatt tctcctacca
    46981 aactagttgt agttgtcttt ccatttgtac ctgtaatccc tataaaaatt ggattattcg
    47041 atagtttaaa agctaattct acctcaccaa ttatatactt gcctgaattt tttaatttca
    47101 atatgaatgg taggtctagt ggtacacctg gagacactac aaccatatct atatcatcta
    47161 catcttctgg gtgatgtcct aatatgtatt ttatgtcatt tatagatttc aattcatcaa
    47221 gtatatttct caatttattt tcatctttta tatcatttac gattatactt gcacccaatt
    47281 tatctaaatg tttaattgta gatataccag tttttgcaag tcctactaat aaaacttttt
    47341 ttccttttaa gtccattttt cattccccct agccctaaaa tactgctatt atacttatcc
    47401 aagctaaaac aactgttata atccaaaaaa taaatacaac tcttgtttct ggccaaccac
    47461 actgttcaaa gtggtggtgt attggagcca tcttaaagaa tctctttctt gttgccttaa
    47521 aatatccaac ttgaatcaaa actgatagag cctccgcaaa ataaattcct ccaattatag
    47581 gtattataag cactgagtta gttagaactg aaaatgctac aactgcacct cctaatgcca
    47641 ttgaacctgt gtcgcccata aacactctag ccggatatga attaaatcct aagaaaccta
    47701 aacatgctcc aacagttgct gctgctaaaa ctgcgacttc tgtatttcca gcaatagaac
    47761 ttgcaaatag cataaagaat acagaaacta ttaatgttac tcctgatgct aatccatcta
    47821 atccatcagt caagtttaca gcatttacta ttgctacgat tataaacatc attattggta
    47881 tatataatat tccaacattt atcacaaaat ctgtaaatgg tatcataagt tgtgaagcac
    47941 ttgatgatga tgtatactga taaaaagcaa cataaaaaga taatgcaact tgaaggatta
    48001 ttttttgata tgcttttagt ccaagtgatc tttttagctt tatttttata aaatcatcta
    48061 aaaagccaat aaaaccaaaa cctgcaatac atataagacc tactgccata tcatgactaa
    48121 cttttactct tgtaagtcca gttattagaa ttgcaacaat cattataatt ccacccatag
    48181 taggtgttcc gtttttagct agatgtgttt ggggtccatc atctctaact gtctgaccaa
    48241 atttaaattt tctaagcatt ggtataaata ttggtcctat tataattact attaaaaacg
    48301 caatcaatgc ggtgtacgta agctctgtta ttcctaacat cataaaactc ctctcccttg
    48361 tcaattaact cattagttta agcttattta tttagatatt cgactatttt ttctaatctc
    48421 atgcctcttg agccttttac taaaatagtg tctcctgttt ttactaattc atttaacttg
    48481 ttaaacacat cttctctatt ctcaaagtga tatatattgg ctgaattgaa tcctaattgt
    48541 tttgcttctt ctccaataaa cactgaattt tcacctatag ttattataat atcagtatta
    48601 ttcatagatg attttccaac taatctatga ccatactctg aaatttcacc catttctagt
    48661 atatctccaa gtatcgctac ccttctacct ttatatcttc caagtatctt taaagcagca
    48721 tccatagaat ctggactagc attatatgaa tcattaatta ttgttaattt ttcatttttt
    48781 attatgtcta gtctcatttt tgtcccttta aaatttttta aacctttttt tatataatct
    48841 aaagaaatat ttagacacaa accaactaat atagcagaca ttgcattata tatattatgt
    48901 tctcctattg ttggtataaa tatttcctct tttttcccat ttattacaca tataaatgtt
    48961 aaactatcct cttccatagt ataactttca caataaacat cattgttttt attaaagcca
    49021 aatgttttta atttatatac atgttctttt tcttttaatg tagataaaaa cttatcatct
    49081 ccatttacaa ttaaagtatt tgtttcatca aagtttgaag taatctccat ctttgctttc
    49141 aaaataccct cttgtgaacc tagtttttct acatgtgata atcctatatt cgatatgact
    49201 gcaattttag gatttactat atccactaaa tattttattt cattgaatcc agacataccc
    49261 atctctatta cagcacactc atgttcttta tttagattaa ataaagtcaa tggaactcca
    49321 aaatgattat ttaagttttt ttcatttttt agtatattta actttgcaga tatggcagag
    49381 taaatcatat ctctagtagt agtttttccc acactacctg taacacctat aaatggaata
    49441 tcaaattttt ctttatagta ttttgaaata tctcctagag ccaaagatgt atcttttacc
    49501 tctattaaat ttatatccga actttctaat tttattccat tactttcatt ttttataaaa
    49561 gttttacatc cactatcata tgcagacttc ataaatgtat gcccatctaa attttctcca
    49621 actatggcta caaatgcatt ttgggcattt gcctccctgc tatctataac tatatcactt
    49681 acacagtcat tataatctcc atatattaac ttcccattag ttgcaagtac taactctttt
    49741 attgttaagc actccattat taaactcctc ctttaaaacc ttagctatat tctcttagca
    49801 acaaaaggca atgtataccg ttatatatac attgcctacg ataactctta actttataat
    49861 tatatactat atttctgttt ttttgaagat gtttatgggt atatgttaat tatctgttac
    49921 tttttagttt tcaaaatata gggttatact tgagtcttca ttaactttta ctccaggttt
    49981 tgggaatata tcctttacct ttgtatcttc tggaagttct atatctgcat ctaagtctgg
    50041 ttttaacttc gcatcctcca atgcctttac agcatctcct atttttagat ttcttacatc
    50101 tggcacttta acttgcttct tttcatactc agctttttct tcttctttat atactggttt
    50161 aactcccaaa tattttaaag agtcattcat tatttctttc actattggtc ctgctgtagt
    50221 actaccaaat gcacttactc ctgttggttc gtcaacaata gcaagaacta ctatttgcgg
    50281 gtcatcacaa ggtgctattc caacaaatga acatatatac tttcctggag catacttacc
    50341 atctataact ttttgagctg tgcctgtttt accaccaagt ctataacctg gtatatatgc
    50401 tatctttcct ccaccttcag ttacaactga ttctgcaatt tctaacattt ttttagatgt
    50461 ttctttagat ataacacttc ttactttttt tggttttact gtttcagtta tatttccttt
    50521 attgtcagta taagatttta ccactcttgg ttgcattaaa tctccaccat tagctattga
    50581 tgatatagct gttataagtt gtattggagt tactgatata gattgaccaa atgatattgt
    50641 agccaattca actggtccta catttttttc gttatacagt attcccttag cttctcctgg
    50701 taaatctata cctgtcttat ccataagacc aaatgattct atataatcat acatttttcc
    50761 aacacctaat ctgcttccta actcaacaaa tactgggttg caagagtttt gtactgcttg
    50821 tttaaattct tgtgttccat gaggtctgta atgtctccaa catttaatct ttcttcctcc
    50881 aacagttaca ctacctgtac atgtgaattt ttctccatct ttaattactc cttcttcaag
    50941 agcactggaa gatgtaataa gcttaaatgt agaacctggt tcatatgtat cacttactgc
    51001 tggatttctc cacatttgat aatagccttt tattttatct ttatcattat atttttcaag
    51061 ttcttcttga taatatggat atattggcgt tcttgagtca ttagggtcat aatctggttt
    51121 tgatgctaaa gcaagtatat cacctgtttt agggttcata gctattgcag taaccttttt
    51181 tgcattattt aactcataag ctttctgtac tgctttttca gtatagtgtt gaattacttc
    51241 atctatagac aacacaagac cattaccttg tacaggctca taatattttt ccattccttg
    51301 tggtatttct cttcctgaag catcagtact tactataagt tttccaggct ttccttttaa
    51361 ctttttatca tattgcattt ctacaccaga tatacctgtt gcatctgaag aagtatgtcc
    51421 taacacatat ggtgcaaaat tcccatatgg gtaatatctt tgattatctt ctgccaccca
    51481 tattccactt aatttagcat ctcttatttg acttgcctta tcatcatcta tccatctttt
    51541 tacttttaca agagccatat tttttttgct tattaaagcg taaatatctt tataatcttc
    51601 atccaaaatc tcagctacct tttcggctgc ttctttttta tcttctactt ccacaggttt
    51661 acaccaaaca gtatacttag ttacacttac tgctaactct ttcatatttc tatcatatat
    51721 agttcctctt ttgggttcta ttggtatatc tcttgtttgt tgttctagtg cttttgtact
    51781 caaccaattt cccttcataa gttgtagata cccagtccta ataacaaggc aaaaaaacaa
    51841 tgcacatgct agaataagaa cgagtaccag ccttttctta cttatcctct ttacttttct
    51901 caaatctatt ccccctagtt atccacatct atatacttta tttgtccatc ttttggatag
    51961 tccatattga gcaattcctt agcctttagc tcaatttctt ttattgatgt tttttcagtt
    52021 tcttttgcct ttagttcctc taatactatc tctttttttc ttaaatcttt ttgtaaataa
    52081 tagatatcgt acttcatttc cgagattttt gaataaccac atagattcaa tattattact
    52141 gaaaaagttg caatcagtaa aatgcattta gctcctattt ttttcttatt tctcttttta
    52201 taattattct tttttttatt tttatattca tttagattat gtattttata attttttttc
    52261 aaattctcac cccgatagta tatagtttaa attttcctct atactatatt tgttattaat
    52321 catatttctt cctctaaaat ttcatcgcta aattaataca ctattacaca atctaattgt
    52381 atttttttct atacacaaca aaaacctata aattcactta tacttttata tgaatctata
    52441 ggttagatat taatttctat ttatttttat cacttctagt atttttagat aatttcttcc
    52501 ataaatataa tatgtaacta gctatctact ctctgattcc taagttctcc attatattac
    52561 ttaataccat ctatatctat atttttatat ctaaattttc attatatatc tcaataacaa
    52621 agaacatttc ttatagtatt aattgttttt taattgcttt accagtgcaa caaaatatat
    52681 aatacttttt aattaattat aataatttta tatataagat tattctttag ccttataact
    52741 acttatattt tttctgctac tcttagctta gcacttcttg aacgtggatt tacttctatt
    52801 tcttcctcac taggtaatat aggttttcta gttattattt tcacctcaga ttctttatca
    52861 cattggcata taggtaaatg ctgtggacat atacaatctg atgctaaatg cttaaatgca
    52921 tttttcacta ttctatcttc taatgaatgg aatgttatta tacatattct tccaccttca
    52981 ttcattatag aagaagcatc atttatcatc tttgtaatta ctccaagttc attatttact
    53041 tctattcgta ttgcctgaaa agttctttta gctgggtgag gtccatctat tctagctttc
    53101 ttagggatag cttttttaat tacatctact aattctcctg tagtttctat tggtttgttt
    53161 gctctttctt caactataaa tttagctata cgcttagccc agttatcttc tccataatct
    53221 tttattatct tagttaattc atcttctgta taagtattta caacatcata tgcagaaaac
    53281 tcacacctaa catccattct catatcaagt ggtgcatctt gcatataaga aaatcctcta
    53341 tcagcttcat caagttgatg agatgaaact cctaaatcag ctaatacacc atcaattttg
    53401 taaactccta ttttttctaa ttcctctttt atattttcaa aattgctgtg aacaaacttc
    53461 actctacttt catattcact caatctctct tttgctgtgc ttatagcatt tttatcttgg
    53521 tcaaacccta taaataatcc cttatctgac aattttttta ctatttcttt agaatgtcct
    53581 gctcctccca tagtacagtc aacatacacg ccatctggct ttatatttaa attctctata
    53641 cactcattta aaagaactga tacatgatga aattccatag ttacctccct taaattcact
    53701 ttttaaacta ttcttcacta atattatttt tatttttctt tgataaataa acatgtgcaa
    53761 ttatgccacc aataactcca attagactta taacttgtgc cattctaagt ggtcctaaca
    53821 ttaaactatc tgttcttaat ccctctataa aaaatcttcc tattgaatat aaagttatat
    53881 aagtaactat aacttgacct tcatattttt tattttttct aaatagtaat aaaactataa
    53941 atattccaaa atcccatata gactcatata aaaaagttgg atgtaccttt actccatcaa
    54001 ccattattcc ccaaggtaaa ttggtagcac ctccatgtgc ttctccatta ataaaatttc
    54061 cccatcttcc aatagcttgt gctaaaggca ttccaagtat aactgtatca gccattttta
    54121 agaagttaat atttttaatc ttagtgtata tataaccagc taatattcca ccaattaacc
    54181 ctccatgtat agcaagtcca ccacctctaa aattaaaaat ttgagacata ttttgagcat
    54241 agtaactcca attaaataca acataataga ttcttgcaca gattagtcca actggaattg
    54301 ctattatagc tatatttaat acatcatctt ctttaattcc cactcttttt gcttctttta
    54361 ttgctattaa agttcctaaa atcattccac atgccataag tattccatac cacatgatgt
    54421 ctatgccaaa cagtgtaaat gctactctat ccataacgtc acctctttgt attaattgaa
    54481 aatatttcca aagcaatatg ctataattac aattaattgt aattatacta aattatgata
    54541 acacattaat gttaattcta caaaaaatat taaaatttat tctacaactc cctacactat
    54601 attatatcta attactataa aattttttaa actgaatctc tcatgactaa agttacaagt
    54661 gtacatagat attttttaat caaaaagatt gatgcatata tacatcaacc tcttctattc
    54721 cttatctata gctcttaaat ttttacctca atttatataa atatatttta taaatttgtt
    54781 ttaccaaaat aaacatttaa aaacataaac taatacttaa ttagttattc ttattatgat
    54841 taagtttcta tttaggctct acaatagaaa taacacaata ctcttcttta aaatgctctt
    54901 ttaatctttc ttcaacttcc tcaaaagtaa tatctttaat aacatctaaa taatccaata
    54961 gatttatatc cttaaaaaca taagatataa aactattacc tataaagttt atagaatcaa
    55021 agcacttaat aaatgaccct atttttttct ttttagttct ctcaaactct tcttttgata
    55081 atccttcttt ttttgatttt tctatataat caagaattat ttcttttact tttttaggct
    55141 ctttagaatc tccagctatt atgctaaaag cataatccac ttgagacgaa aatccagctc
    55201 caaaattttc atttattaaa ccttgcatat acaaatcttc ataaagctta cttccttttt
    55261 taaataacat ccctacaagt atatcagtta caatctcttt acgtaaaagt tctttccctt
    55321 ttaaaccaac attgctatct ttaaaaccta tgttgaacat aggcatagat atagggaatt
    55381 tttctataac ctctttttct tttacacttt ctggttcttc tggataaaat ctttctatac
    55441 tcttagagag tctgtctact ttgtaattgt ttgacttttt agttacatct ataacttttt
    55501 ctacatctaa gtcaccaaca acaaataaag ccatatttcc tggattatag aaagtattat
    55561 aacatttata tagctcttcc ttagttatct tatatatact atcaacagta cctgctatat
    55621 caattctagc aggataattt acatacattg ccttcaagca attaaagtat acattccaat
    55681 cagggtcatc attgtacatt tttatctctt gtgctattat acctttttcc ttttcaacat
    55741 tttcatctgt aaaataaggt gtttgaacat agtcaattag atgttctaaa ctctcataaa
    55801 aattttcagt agcagaaaat aagtaggctg tcattgtaaa attagtaaat gcatttgcat
    55861 ttactcctaa ttttgaaaat ttatcaaatg catctcctcc atcaggttgc tcaaacatct
    55921 tatgctctag aaaatgtgca ataccttcat tcactctaat tttcttatct tctccaattg
    55981 gtacaaattc taagtcattt gaaccataat tagtagctaa aatagcatac tttttcataa
    56041 aacccctttt aggcataaaa tatacatcta atccattttg caatttctca taataaactt
    56101 cttctttcaa tatatcatta actatttttt ccatagacat ctcctccatt aatttctcaa
    56161 gaagtataca gtatcaagct ctatattttt tatagcttca actatatctt tttttgtaac
    56221 cttttctata ctagatatta tgtcttgtac ttcagaattt gtctttgcca tagactgaga
    56281 gaaaacaaaa tcagacatac cacctatatt atcagttata gatttcatag aattaactaa
    56341 agcaagttta ctgttttcta attcttcatc agatatatca cctgctttta cactttctac
    56401 ttgttttttt atcaattcta cagctttatc ataatcttta gtttctatac cagatgatat
    56461 aaacatgata cttttatact tctctattga agagaatata tagtaacata aactttcttt
    56521 ttctcttaca ttaacaaata atttagagtg tggaccacca cctaagacat tgctcccaac
    56581 tactaaagca taatatttat ctatgtctgc ataatccaca tttgctctat aacccataac
    56641 taacttacct tgagttattt ccatttgttc atctataact tttacctcat ccacattttt
    56701 tataaaatct gctcttggta tatttataat ttcttctctt tcaaatttta gatttttact
    56761 tattatatct acaactttat cttcatcaaa attaccttct acaactatat ctataggtga
    56821 tgttttaagt atgtttttat aatgttcata taactctctt gaagttatac tatctatttc
    56881 atcttcataa ccaaattcac ttacactata tctctctcct ttacacatag cctcaataca
    56941 tttatcttgc gcatattcct ttttatcatt tattattgat tgtatctttt ctcttaaatt
    57001 ctctttttca atatttaaat attcttcttt aaacccacca tctacaacaa gcgtattatt
    57061 tattacttca ttaaaaaatt ctactacttc ttcaaatata ctctcatcta aatacttttc
    57121 acttatgtta attactttaa aactcaatac ttgacgttct ccacgtttta cagcatcagc
    57181 tcccatagat gaaccatata aatcatctaa tttattggat attgctctag cactaggata
    57241 tttagcgctt ccacttgcta ttattgatgg tattagagca ttttttgtag tttctttttc
    57301 atccaatagt ctctgaacat ataaacttat aagattcgat ttaaactttt ctgtttttat
    57361 caaagtaaga ttaatattat tacctaaatt tattattttt ttagtattaa ccatatgtac
    57421 ctcctatttt tatttaaaca tcaattttaa aattgaaatt tatttatttt ttaattacat
    57481 atacccacat ataaaaacct tctatttaat tatatccttt ttattatttt ctaaaagcaa
    57541 tatttttatt taaattaaat acaaatatta tttaaatcaa tatgctttaa agtctagttt
    57601 acaagcttga tatatatgat gtataatcaa tatgtatgtc tataattaaa acaattttgc
    57661 aatcctatag attgattgtt taaagttata taaagaatat aaaaaagaat aagagagagg
    57721 acgattaata tgaaattagg tatagttggt ttaccaaatg taggtaaaag cacactattt
    57781 aacgcaataa ctcaagcagg tgcagaatct gcaaattacc ctttttgtac aatagaccca
    57841 aatgtgggag ttgtatctgt tccagatgaa agattaaaca aactacaaga attatataat
    57901 tctgaaaaaa tagttcctac tgctatagaa ttttgtgata tagcaggttt agttagagga
    57961 gcttctaaag gagaaggttt aggaaataaa ttcttatcac atataagaga agttgatgca
    58021 atagttcatg ttgttagatg ttttgaggat gaaaatgttg tacatgtaga tggttctgta
    58081 gacccacttc gtgatataga aactataaac ttagaattaa ttttctcaga tatagagatt
    58141 cttgaaagaa gaattaataa aactcaaaaa gctgctaagg ctgataaaac tttaggttct
    58201 gaacttgatt tattaaaatc aataatgtct actttagaag aaagtaagtg tgtaagaact
    58261 atggaattta cagaagatga acaaacattt gtaaattcat tggatttact tacatctaag
    58321 cctgtaatat atgcttcaaa tgtatcagaa gatgatttag ctgataatgg agaaaataat
    58381 aaatatgttc aacaagttaa agcatttgca gaaacagaag atgccgaagt tgttgtagta
    58441 tgtgcacaaa tagaagcaga aatttctgaa cttgattctg ctgaagaaaa gaaagagttt
    58501 ttagaaacat taggtcttga acaatcaggg cttgataagc ttataaaatc ttcttatgct
    58561 ttacttggtt taatttcatt cttaactgct ggtccaaaag aagttagagc atggactata
    58621 aaagttggaa gtaaagctcc tcaggcagga ggaaaaatac attctgatat agaaagagga
    58681 tttatcagag cagaaacaat agcctttaat gatttggttg agcatggtac tatggctgct
    58741 gctaaagaaa aagggttggt taaattagaa ggtaaagaat acatagttaa agatggagat
    58801 gtaatattat ttagatttaa tgtttaaaat gattaatcgt atacactttg actattatat
    58861 ataataa
//
LOCUS       DAEORM030000019        58745 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.019, whole genome shotgun sequence.
ACCESSION   DAEORM030000019 DAEORM030000000
VERSION     DAEORM030000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 58745)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 58745)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 58745)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..58745
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.019"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            <1..1699
                     /locus_tag="KRH23_001629"
     CDS             <1..1699
                     /locus_tag="KRH23_001629"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008745 - N-acetylmuramoyl-L-alanine
                     amidase activity [Evidence IEA];
                     GO_process: GO:0009253 - peptidoglycan catabolic process
                     [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HHS5224910.1"
                     /translation="VWELQGITINSKNNPKTLNKQELEKMGLNLKDYNVTQECIIEDI
                     TSRKDVNKYLRKTSSPITELTGSDRYETAVKISKEGWKNGSDKVVIINGDVSIDGIIS
                     TPLATTYNAPILLVEKNNVPNSVKSELKRLNPKDIIIIGDENAISKTTANQIKSTVNA
                     SQTRLNGSNRYETSLLIAKEIDKNHDVEKVYITNANGGEVDALTIAAKAGQDKQPIIL
                     TDKDSITDNTYKWLKSEDLQNAYFIGGPQMISTNVINKVNGITKDSVTNNRVYGADRH
                     ETNANVIKKFYTDDELEAVLVAKSDVLVDALAAGPLAANLKSPILITPKTYVSAYHKE
                     NLEAKSANKVYKIGGGLTSKVMSSIASSLSKHNTTPTEPGNSGGKTVMIDPGHGGSAP
                     GNSSGGMIEKDYNLNTSLATTEYLRSKGFNVIMTRDTDKTLSLGNRTDLSNSLKPDLF
                     TSIHYNGSTNKQGHGVEVFYKLKDKNGGTTKTVATNILNRILEKFKLTNRGIKTRVLP
                     SDSTKDYLYVLRSNDMPAVLVECAFLDNENDMSLINSSAKVKEMGTQIGKGIEDSLK"
     gene            1941..3854
                     /locus_tag="KRH23_001630"
     CDS             1941..3854
                     /locus_tag="KRH23_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224911.1"
                     /translation="MEYLFEKSSLKEYGNEALDKYRELLDKTDNNSRCILLLVPNNNT
                     KIRYERALRLNYSEELKITTYISFVKKELVKYWPLIIEKCDEISTKAVSPTFISNSLS
                     EYLIVQKVKEKRIQEGYFEDITGTNKSIANSIMTNINKSAFNLIDFDFIGEKIYSSKK
                     NKDSIYRFSYTQMDEIISYYINSLLSNSILDNALSIYLYNQYLLNDDFYLKNLFTEVR
                     YIIVDSLESSSNAEVDFITEALDNTLQSYIYFDYSRDYSVFNNVDIDYINEKIISKIK
                     PKEENIKKKEIRIEDLYLLPANIELNQSSQLYNEMLDLISEKVTSLIEEDVSPRDIAI
                     ISPINNSILEHQIRDSLIEKNIDVFSTKKDKKAVDYPYGNALVVATCIFYGYLDFIKD
                     DEYLSFLETLLEINRIKAFKIFNETRHLSIDNIDEHSQYRDILQYIEEKKKSDIKIHE
                     FLTQFYIDKMLNLKEGKKNVGLCKKIIAESESFSESLSLLGMKKEKIFVEALKSTIND
                     YYSVVDIEELKSKDKIVITTPYSYISSNIDRSIQIWVDIGSNAWNMKIEKDISNLIVL
                     RKSFEEKKIYTNEMEEYYKKYYLYNTVYNLLLNAKKIYAFKSEYAINGYIQESILYSI
                     LLKISHKGDKNYD"
     gene            3847..6066
                     /locus_tag="KRH23_001631"
     CDS             3847..6066
                     /locus_tag="KRH23_001631"
                     /EC_number="3.6.4.-"
                     /EC_number="5.6.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HHS5224912.1"
                     /translation="MININYREDQIPIINYDNGTMAVPAVPGAGKTFIITNLVAKLLL
                     EQKHKGGKILILTYMNSAVNNFKGRIRKILEENKIDDTNSYEVMTIHSLAVKIIKEKP
                     EVVMLSEDFNIADDLQKSIILNECISRFRFEGGERAFRWFLKEQKDERWKEITLEAWE
                     RGFFEFAGNAISELKYKGISPDNLEEILSRGHKGMLKIILPIYKLYDRKLKQNGLLDY
                     DDILILAEKTLSLDEGLRKKFQTRYKYIFEDECQDSNEIQGNIIKIISSENKNLVRVG
                     DINQSITGTFSSSDPKFFKEFINSADFCYRMDMSNRSSKDILDLANTLVKYVTKEFRQ
                     EECRHALEDMQIKTVPNGMGYKENPNPEHYNINVKWYESWKIEIEQTARYVKGIKNKY
                     PDKSIGILVPFNEQVTQVAKELRENNLTFEELGPNSLNKRKVINNIAYIIDFMLHCDD
                     VEKLIVVLNKVFIDTDNEEEIKYFLEELKNYSTEEIIYNFEFSKLDNDLIEFKEESDI
                     YLSFKRGIDIIKQILEYPIIRLDLLVLFIGKKLNLEKEDKAVLDYISFYIKYLVSENI
                     NMDLEDVYNLLFDVKNRVFNHIIDVVYEINGYEPEPGSITLCNYHKSKGMEWDCVFLL
                     GLVEYNFPDNINQKFQSDKWYLKEKYKNPMAIIKSEVEAILKGSISTDYAHKTKIDSI
                     NEKIRLLYVGITRAKEMLVLSGSAYRDESDIGNKRKEQKPCIYLSRLNQHIIEKRSN"
     gene            6175..7005
                     /locus_tag="KRH23_001632"
     CDS             6175..7005
                     /locus_tag="KRH23_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
                     /protein_id="HHS5224913.1"
                     /translation="MNDKLKYFSYSQNSINTYKSCPLKFKYKYIDRINWKNDDVGSRE
                     YYETLKTGRDFHLICERYFSNIPLGIYFNEDDKNSKKFLKWMENIKKVVPIEKGKTYL
                     PEYEVRMTLNGDIIQAKYDLVVIGNNNIEIWDWKTESKKIDYKHVENRIQTIVYMFLA
                     KEVIPKVLKMDINVKDINMRYYQPEFDDLPITILYDEEKHEANRNKIQNYISMIKNTN
                     YEEHTYEDNLYNDIEKVYNKEERMCYRNKKHCKYCEFNKLCNGKEIDYSILEAEIYGT
                     "
     gene            6995..10462
                     /gene="addB"
                     /locus_tag="KRH23_001633"
     CDS             6995..10462
                     /gene="addB"
                     /locus_tag="KRH23_001633"
                     /EC_number="3.1.-.-"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004527 - exonuclease activity [Evidence
                     IEA];
                     GO_process: GO:0000724 - double-strand break repair via
                     homologous recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddB"
                     /protein_id="HHS5224914.1"
                     /translation="MGLRFVLGRSGSGKSTYILDEIKKEAQKNETTSIILLVPEQYTF
                     EAENRVSKLFLGKEKDKYLRVRVLSFKTLSNIVFSQVGGLTDVNINSSGKAMMVYRAI
                     EDVSEELNVFSKSKSQSGFVSSITDMISEMKQYNISPEMLENISGELDNETLSLKLKD
                     ISKIYNSFEGKLHENYVDAQDMLTSLASKIELSSYLDGACVYIDEFTGFTPNQYNVIK
                     SILNKSKSVNISLTVDDINYIGYSKSDMFSRTKFTYSKLTQLCNEEGIKILPQVNLNT
                     GVIKRFEKVKELQHLERFYNAYPYKIYSNPTENIKIKEFNNLYSEVEEIAREIVHLVR
                     DKNVRYRDITIATRDLNRYDFLVHSIFNEYNIPNFIDKKREAKSNPIVILIISALEMK
                     NRRYGYETMFRYLKSGLIGIDNDDINLLENYVLANGIKGKKWFDEKWDYRITQSLSGQ
                     ESEFELELKEKINEIKNRVLEPIVILQEKLRGKNRVKEICRYIYEFLLDINMPETIES
                     LIVNFKDKGELDVANQYSQVWDIVVDILDQMVELMGDEIISLEKFIKLITLGFDEYEL
                     GLVPPSIDQVLVSSVDRMKNPDTKYLYLVGTTDGVFPLITKDSGILSDNDRESLGNKG
                     IEVDIDSKTRSFEEQFLVYKALTSTSKNLTITYPISDHEGKTLRPSIIISRLKKIFPN
                     IENKSYLVEENKSTDKDILKKITVKSPTFNELINIIKNYDSDGYNTEEINSIWLDIYR
                     YYLKDEVYSSITKKVIKGLSYTNQVHKIEEKKIRSLYKSNSLSISRLEKYAECPFAYF
                     IQYGLKAKKRKEYSFTPPDLGTFIHNILDRFSKELLQDNLTWRDIDEKYIELKIGIIV
                     DEIILKIPGYILNSSERYKYLAYRLKNMLTTAITIISQQIKQGSFEPIDYEVKFGDNG
                     KYPPIKMVLENGQEVSLIGQIDRVDEFEEGENKYIRIIDYKSGNKSISLTEIYYGLQL
                     QLLVYLDAILESTKDEDININPAAILYCRINNPIAKFNEDKDDEEIQEAILKELRMKG
                     LVVKDSHIVKEMDKSLIDGERKNSLVIPVGLTKDGNVGKSTSAISYEDFKLLRKYVRH
                     AIKDLCEEMLSGEIRIAPYKHKDGTSCDFCDYSAICQFDSTIKDNKYKNLNNKSNEEI
                     IKMMKGDVN"
     gene            10462..14289
                     /gene="addA"
                     /locus_tag="KRH23_001634"
     CDS             10462..14289
                     /gene="addA"
                     /locus_tag="KRH23_001634"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0016818 - hydrolase activity, acting on
                     acid anhydrides, in phosphorus-containing anhydrides
                     [Evidence IEA];
                     GO_process: GO:0000724 - double-strand break repair via
                     homologous recombination [Evidence IEA];
                     GO_process: GO:0006302 - double-strand break repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HHS5224915.1"
                     /translation="MSSPKWTKEQLEVIESRECNLLVAAAAGSGKTAVLVERIIQMIT
                     SRENPIDIDKLLVVTFTNAAASEMRERIGDAIGKALDENPENKHLQNQLVLLNKSSIT
                     TIHSFCLDVIKSNFHRINLDPNFRIGDQTECAILKQEAIEEVFEDLYEERDEGFLNLV
                     ESYAERGGDKEVQDIILGIYSFAMASPEPKKWLIDSAERFNIDENFDFSQSIWARAIL
                     DTVKIEINGLCLNMERALKEVESIEELETFAEKLSVEYKKIADISQACNKSWDEAYKK
                     MASMSFENYVKGVKRISKDAPSYIKESKEKAKTIRDKTKKSLESIVSATFNKDNDSIR
                     EEIKYLYNIVKPISSVVLRFEEEYSNKKREKGIIDFNDIEHFALNILTDVDEKGNIVP
                     SDIAVGYRNKFYEIFIDEYQDSNLVQEVLLKAVANTETPNRFMVGDVKQSIYRFRQAK
                     PELFLQKYNNYNDKKGSSHRKIMLYKNFRSREEVVDAVNYIFENIMNENIGEIEYTEK
                     ERLNLGADFNVDTDEKSIIGGATEIHLIQKDNKLDDDIINDKDDRINNKENEIEEEEK
                     LDNIQLEARMVGNIIKDLMKVNEDGKIQKVYDKGIDGYRPVEFRDIVILLRATSAWAP
                     VFADELMNMDIPTYADVGVGYFDTIEIKTILSLLQIIDNPMQDIPLISVLKSPIFGFT
                     PEDLIDIRVQSKDKIFYEVLKSTAEYDGFTDSQNENESEFIPSEECINKSKDFLIKLK
                     EFKEKSMYMSTDEFIWYLYTRTGYYAYVGALPGGSQRQANLKVLFERAKQFEETSLKG
                     IFNFVNFIEKLKKSSSDMGSAKTLGENANVVRIMSIHKSKGLEFPVVICSAMGKNFNT
                     QDFKKSILYHHNLGYGPQFVDYERRISFPSIAKEALKSKINIENLSEEMRVLYVAFTR
                     AKEKLIITGSTRNIQDSIKRWSNGIESLDTISQYEILKGKNFLDWIMPCVLRHRDLYN
                     LLEEVGLDAVFNVEHNSKWYGKLWNKNDILVEKKSDEEKESIEEILEKIDVDNPDSDY
                     YSEIEEKLNYIYPYEFSTRKPATISVTEIKKIQNNYEEELINTIFEQKVILKKPLFIQ
                     NEEEREKISGTERGTIVHLVMEVLDLKNVSSVNDIKSQIRGFVSKGIITEKQASIVNP
                     YKIYKFFASNIGKRMLNAEIINREKSIYAQVNMKDIYIYEKLINNDDKKLYDNESVML
                     RGIVDAYFEEDNQIVLVDYKTDFVNEENINQIIEKYKKQLDLYADIIETLTGKSVKEK
                     CIYLFGVDEAVCY"
     gene            14335..15546
                     /locus_tag="KRH23_001635"
     CDS             14335..15546
                     /locus_tag="KRH23_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0004529 - DNA exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HHS5224916.1"
                     /translation="MRFIHTSDWHLGKSLEGHSRIEEQAKFCEEFIKIVESNEIDMVI
                     IAGDVYDTSNPPAQAEKLFYQTVSRLANNGQRCVLIISGNHDNPERLSAITPLAHEQG
                     ILIYGYPLSATIEAKYKGFEITYATQGCTKLNINGENIVVATLPYPSEKRLNEVFSSE
                     DEFEKQKNYSEKVGDIFRSLEENFRSDTINIAVSHIFVIGGESTESERPIQLGGSFLV
                     ERKDLPEKAQYTALGHLHKQQKASERLNAYYSGSPLQYSKDERAYTKGAYIVDIKAGE
                     KPIIEDVYFNNYKPIEVFKCNGIEEALDICEQNQDREIWSYFEINTDEIISQNEIKKM
                     KELLKDIIEIKPIITSCYEQESVDIKEKSMAELFREFYSFSKGVEPKGELMDLFLDII
                     SEEGESADETN"
     gene            15533..19060
                     /locus_tag="KRH23_001636"
     CDS             15533..19060
                     /locus_tag="KRH23_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006302 - double-strand break repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HHS5224917.1"
                     /translation="MRPIRLELTGLNSYIDKQVIDFEKLIERGLFGIFGTTGSGKSTI
                     LDAITIAMYGNISRNTKEYINSVCDKAIISYEFEIGSKNTRRRYIVDRTIARSKTGTK
                     TSNARLIEVLNDNTQNVLADKVVEVNEKVAQVVGLTANDFTRSVVLPQDKFNEFLRLS
                     RADRRDMLERIFNLEKYGRSLGEKVKKRKNIQLQNLKDLKSKLSQYDGITEEVYNKIN
                     QELIELKNLEKDKNNALDLAQKSYEESKTVYEEQLKLEKNELRKNELDLKNSEIKEKI
                     ALVENDSNAKKVDPYISSVQNLEKKIDEDSFAVSNLEKKLAILNQELEVTKNRYEKIN
                     KIKNEEVPKLSEEKIRLQQAMKLEEELVLLDRELKELKESGINLNKTKVELEKVKQVS
                     ESRKDAVTKSIKEVEGKIDKVNISAELKQKIFLAYEYEKDYNNVLEEKNQKLNKLEEI
                     LKETENINLKVRYIDKGKNDVNRNLENLSLHLDVLLKKCPGKSADLLLKSEYVTELRN
                     KANNTKENEIKKSSIQDELKIILESKFNTEREVNLLNEKLENNRKNRDDLEKELEELK
                     YLNLASELRRELKENMPCPVCGSKHHENHDITKYDENISFVKEKLEKLEKEKISIRNN
                     IEELNAKVSGYLSIEKMKTKELEDVKGKLGGIPSSQLLKKLDEEQRKLALLKSNIQEW
                     EKEKESTENKVTLAKEEKNKIEKEELKIRESLNNYKKLTRDLNIEIEGLENKCKKIKQ
                     EYLGLKTITKVSNLLSKVKEIRENEKELELLSTGHSNLLKNRDSLDIKIRENESKLHE
                     IEIELIKARELYVEKKLSRDNKYKEVISITKGDLAKNLLHNVEENICKILEQEESSKK
                     KLEEQRLEYEKNIAEKHNIDGRLKTAKEQYKDQKSTLNKLLAENKFESIYAVKRALLD
                     TDAVKKLIEEILEHEEEQKLLSFKIKSSKEKLNGRSIKKEYFEQLKDEIYNLKVEIGN
                     ISKDIGANQNQLITLKDSLDKINDFNKQLKVVEHNVDLLEELDKCVQGNKFVEYVSTN
                     QLKYIALEASKRLDGITKGRYALEIDSTLNFIMRDNFNGGERRSIDTLSGGETFLTSL
                     SLALALSSQIQLKGSAPLEFFFLDEGFGSLDSELLEIVIESLERLHSNNLSVGIISHV
                     EELKNRVPVKLLVSSSEAGIGSKVKIEYS"
     gene            19191..20444
                     /locus_tag="KRH23_001637"
     CDS             19191..20444
                     /locus_tag="KRH23_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HHS5224918.1"
                     /translation="MLESPNNLIQIIFLIVLLIGSAFFSASETALMSLSKIRIRYMQD
                     EGVKGAKLVSSLIENPNKLLSSILVGNNVVNIAATSISTSLFIGLMGEKGVALATAVM
                     TVLVLIFGEITPKTIAANNSEKVSLLVSKPIKAIIFILRPIVWIFNIITNIIFKLFGI
                     TNKGAKSFITEEELKTMVNVSHEEGVLEMEEREIINNVFEFGDMQAKNAMVQRIDMVA
                     IDMEDSYDEIIQVFKTEKLSRMPVYEETIDDIVGILNIKDIIFLSDEEIESFDIKNYM
                     REPFFTYEFKKITQLLEEMKLEKSQMAIVVDEYGGTSGLLTIEDLVEVIVGDIEDEYD
                     EEEDEIQVIKEDEYIVDGSTKIGDVNELIGVNLESEEFDSIGGFIIGHLSRLPEENEV
                     IEVDNIRFCIESIEKNRIKKIRIYT"
     gene            20593..21645
                     /gene="ytvI"
                     /locus_tag="KRH23_001638"
     CDS             20593..21645
                     /gene="ytvI"
                     /locus_tag="KRH23_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation integral membrane protein YtvI"
                     /protein_id="HHS5224919.1"
                     /translation="MSILENNFLYKLKNNTIFFCIYTLLFIFIYKAFPYIAPFFLGAI
                     IALMINPISQKLENKFRINKGISTLVLSFLAVAIVSTVTTIIVINSMKELMGFLNNIS
                     ANPEDISNTIMYFLNKINDFMKSFQEIANFDVEQLVNKFSGEVMQITKNLLTSILGLA
                     TSIPYIIIFIITLFIATYFIAKDLDKIENSFYNMFTVDVRKKVKNVKKEAGLSLVGYI
                     RAYTILMAITFFAIWGSFALFGLKYGLIVGFVGALMDLIPFLGIITIYLPVIVYYFLI
                     KNYFIAISMTVIFFVLSLIREILEPKLVSVNVGLNPLATLAAIFIGIQVKGIIGVIFC
                     LGLVCMHDILKKVDIF"
     gene            21735..22961
                     /gene="pepT"
                     /locus_tag="KRH23_001639"
     CDS             21735..22961
                     /gene="pepT"
                     /locus_tag="KRH23_001639"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0045148 - tripeptide aminopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HHS5224920.1"
                     /translation="MKQKVVERFLKYVSFDTTSNSQCENCPSSEGQRVLAKYIVEELK
                     TMGVDDVSLDENSYIMATLKGNTDGVDTIGFISHLDTIEDVSGKDIKPRIIENYDGKD
                     IVLNEALNVITYVKDSPELEEFKGDDLIVTDGTTLLGSDDKAGIAEIVTAIEYLINHP
                     EIKHGDIKIGFTPDEEIGRGADLFDVEKFGAKYAYTLDGGIVGELECENFNAANATIT
                     IHGRNVHPGSAKNKMVNAIHIAAEISEMFPADERPETTEGYEGFWHLNSIGGNVENVS
                     MAYIIRDHCREKFENRKSIMIKNIEKINKKYDNRVELDLKDSYYNMKEKIEPVMFIVD
                     IAKEAMEELGIKPRLVPVRGGTDGARLSFNGLPCPNIFTGGLNFHGKNECIPVSSMEK
                     ATKLIVRIAEKYAERV"
     gene            23168..24220
                     /locus_tag="KRH23_001640"
     CDS             23168..24220
                     /locus_tag="KRH23_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp18"
                     /protein_id="HHS5224921.1"
                     /translation="MKIKSKKIIAFALSLGIMVPSCVYADTISKNQNAQVDMNNYLQG
                     RKSPKEEKLIGEDRFDTAIKISQSGWNNGSERVFLVNSNSLPDALASTPLASKLDAPI
                     LLTNKNSIPYNVIEEIKRLNPAEVILIGSEGAISSSVKESLEDMEVLVSRIGGADREE
                     TSLLLTRQLDDTGDLGVSKVAVVNGYNGLADATSISSPAASDNTAIIYTGKDSIRSEA
                     KNFITQNSTKTYIVGGEYSISKKLEGQLVNSERLAGTDRKDTNAKVLEKFYGKSSKVN
                     NMYFAKDGSGREADLVDGLAAGVLASKTKSPVVLASGSLSSAQKSFIKKVKADKFVQV
                     GGGKNSKPYAEALALQ"
     gene            complement(24597..25166)
                     /gene="yfcE"
                     /locus_tag="KRH23_001641"
     CDS             complement(24597..25166)
                     /gene="yfcE"
                     /locus_tag="KRH23_001641"
                     /EC_number="3.1.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphodiesterase"
                     /protein_id="HHS5224922.1"
                     /translation="MKIGIMSDTHGSLLYFEKALNVLSDCDVLLHGGDVLYHGPRNDI
                     PEGYNPKKFIDTLNKLENIVIVKGNCDADVDQMVIEHPIQSPYVMSQFSEIRIILNHG
                     YIESEEEIIDKAKKMGGDILVLGHTHVKKLYMDDNLIVINPGSTSIPKDGSHSVAIID
                     IIKTDDEDELELDINLIDINTGNIININD"
     gene            complement(25191..25991)
                     /locus_tag="KRH23_001642"
     CDS             complement(25191..25991)
                     /locus_tag="KRH23_001642"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0006741 - NADP biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019674 - NAD metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(+)/NADH kinase"
                     /protein_id="HHS5224923.1"
                     /translation="MKRIITINTNQLNKSLETKELLTRKLINAGFEVYSDIYPDTELI
                     ISIGGDGSFLRTVRDFDFPEIPIMGINTGHLGFFPDILPDKIDSFIEAYTKKDYIIQE
                     MSLLNAEVYTTTSGSNMLAVNEVVIRGDKSRTIHLNLSLDNKHIQNFSGDGMIISTST
                     GSTAYNYSAGGSIVDINLELMQITPLHPINTNAYRCFTSSIICSNESVIKIAPEYRFE
                     DSVLIVVDGVEHRFRQIENIKVSISDAKIKLLRMSNYEFWHRVSEKFL"
     gene            26126..26986
                     /locus_tag="KRH23_001643"
     CDS             26126..26986
                     /locus_tag="KRH23_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHS5224924.1"
                     /translation="MFSIRNITKKLGKFKLNNINLELKEGDIVGIIGPNGSGKTTLIK
                     IIMGIIDADEGEIELCNETIENSPISFKNNIGFVYDSLQFYPHLKVKEFRKIVSLFYK
                     NFDRERFDEYLNKFDIEENMHIENLSKGQSEKLMLSSALSHNAKLLILDEPTAGIDPI
                     VRTEIMQYLQDFVKNGSSSVIISTHNTDNLIKIVDYLVFINRGNQIFTVKKELIEQEY
                     KIIRANKAELEAIKESIVGVKEYKYYNEALVKVGDSLKVKSLLIEIDKHKVKNPTIEE
                     LMYYYVNEVR"
     gene            26986..27672
                     /locus_tag="KRH23_001644"
     CDS             26986..27672
                     /locus_tag="KRH23_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 transporter permease"
                     /protein_id="HHS5224925.1"
                     /translation="MFNLIRKDLIIGISSDGIRNLKYILLFFVFYFFLNSISYYTVSI
                     VVSYLIFINTFECDYENDSRIFIRSMPVSIEDIVYSKYLLGVGLIISVTIIVSLLSKL
                     TSLVFFRNMVLNDVFFSVNIFLAILTILLPLIFKFGYGKMKVCGFIVSILIYFVYGSL
                     LKMISMIVYQVKHFNYSKVGGVYLSNYVTDIANTKYINLYSMTFLTIIIFIISMYFSI
                     KISKKNKFNY"
     gene            27724..28266
                     /locus_tag="KRH23_001645"
     CDS             27724..28266
                     /locus_tag="KRH23_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224926.1"
                     /translation="MKKFIKVSFFILGIFTLFIAINKLVYRDMVSVKDYEINHLEEIV
                     FDFDSRRSRDVGTIVRFKISNNSKYSYKLNSAKMKFENCVENKKGMNKCSAYVNVDLF
                     NEKNSITERTLKYGIKPNNQGYVDFVIPKGLNFDYRYFNESGMSVEYKGEYIVNIPMA
                     KGLYLVVGKNNDTWNANIME"
     gene            28345..28812
                     /locus_tag="KRH23_001646"
     CDS             28345..28812
                     /locus_tag="KRH23_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaK/EbsC family protein"
                     /protein_id="HHS5224927.1"
                     /translation="MSISNVREYFKQFGKEDSILEFEQSSATVELAAEAAGVIPARIA
                     KTLSFKIGDDAILIVTAGDAKIDNKKYKAEFNCKAKMLTPEEVLEFTGHAIGGVCPFG
                     LKNSIKVYLDDSMKRFDTVFPACGSSNSAIELTCEEMEKFSKCEKWVDVCKNW"
     gene            29521..30657
                     /locus_tag="KRH23_001647"
     CDS             29521..30657
                     /locus_tag="KRH23_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase"
                     /protein_id="HHS5224928.1"
                     /translation="MDLNSKKYQMLKELYVSFAENEVKPLATELDEEERFPYETVEKM
                     AKAGMMGIPYPKEYGGEGGDTVGYIMAVEELSRVCGTTGVILSAHTSLGSWPIYQYGN
                     EEQKQKFLRPLASGEKLGAFGLTEPNAGTDASGQQTTAVLDGDEYILNGSKIFITNAI
                     AGDIYVVMAMTDKSKGNKGISAFIVEKGTPGFSFGVKEKKMGIRGSATSELIFEDCRI
                     PKENLLGKEGQGFKIAMSTLDGGRIGIAAQALGLAQGALDETVKYVKERVQFGRPLSK
                     FQNTQFQLADMEVKVQAARHLVYQAAINKDLGKPYGVEAAMAKLFAAETAMEVTTKAV
                     QLHGGYGYTRDYPVERMMRDAKITEIYEGTSEVQRMVISGKLLK"
     gene            30716..31498
                     /locus_tag="KRH23_001648"
     CDS             30716..31498
                     /locus_tag="KRH23_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009524639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta"
                     /protein_id="HHS5224929.1"
                     /translation="MNIVVCIKQVPDTTEVKLDPNTGTLIRDGVPSIINPDDKAGLEE
                     AIKLKEEMGAHVTVITMGPPQADMALKEALAMGADRGILLTDRAFAGADTWATSSALA
                     GALKNIDFDIIIAGRQAIDGDTAQVGPQIAEHLNLPSITYAEEIKTEGEYVLVKRQFE
                     DCCHDLKVKMPCLITTLKDMNTPRYMKVGRIYDAFENDVVETWTVKDIEVDPSNLGLK
                     GSPTSVFKSFTKSVKPAGTIYNEDAKTSAGIIIDKLKEKYII"
     gene            31517..32527
                     /locus_tag="KRH23_001649"
     CDS             31517..32527
                     /locus_tag="KRH23_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit
                     alpha/FixB family protein"
                     /protein_id="HHS5224930.1"
                     /translation="MGNVLVVIEQRENVIQTVSLELLGKATEIAKDYDTKVSALLLGS
                     KVEGLIDTLAHYGADEVIVVDDEALAVYTTEPYTKAAYEAIKAADPIVVLFGATSIGR
                     DLAPRVSARIHTGLTADCTGLAVAEDTKLLLMTRPAFGGNIMATIVCKDFRPQMSTVR
                     PGVMKKNEPDETKEAVINRFKVEFNDADKLVQVVQVIKEAKKQVKIEDAKILVSAGRG
                     MGGKENLDILYELAEIIGGEVSGSRATIDAGWLDKARQVGQTGKTVRPDLYIACGISG
                     AIQHIAGMEDAEFIVAINKNPEAPIFKYADVGIVGDVHKVLPELISQLSVAKEKGEVL
                     AN"
     gene            32546..33343
                     /locus_tag="KRH23_001650"
     CDS             32546..33343
                     /locus_tag="KRH23_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase-related protein"
                     /protein_id="HHS5224931.1"
                     /translation="MSTSDVKVYENVAVEVDGNICTVKMNRPKALNAINSKTLEELYE
                     VFVDINNDETIDVVILTGEGKAFVAGADIAYMKDLDAVAAKDFSILGAKAFGEIENSK
                     KVVIAAVNGFALGGGCELAMACDIRIASAKAKFGQPEVTLGITPGYGGTQRLTRLVGM
                     AKAKELIFTGQVIKADEAEKIGLVNRVVEPDILIEEVEKLAKIIAKNAQLAVRYSKEA
                     IQLGAQTDINTGIDIESNLFGLCFSTKDQKEGMSAFVEKREANFIKG"
     gene            33441..34286
                     /locus_tag="KRH23_001651"
     CDS             33441..34286
                     /locus_tag="KRH23_001651"
                     /EC_number="1.1.1.157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006631 - fatty acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxybutyryl-CoA dehydrogenase"
                     /protein_id="HHS5224932.1"
                     /translation="MKLAVIGSGTMGSGIVQTFASCGHDVCLKSRTQGAIDKCLALLD
                     KNLTKLVTKGKMDEATKAEILSHVSSTTNYEDLKDMDLIIEASVEDMNIKKDVFKLLD
                     ELCKEDTILATNTSSLSITEIASSTKRPDKVIGMHFFNPVPMMKLVEVISGQLTSKVT
                     FDTVFELSKSINKVPVDVSESPGFVVNRILIPMINEAVGIYADGVASKEEIDEAMKLG
                     ANHPMGPLALGDLIGLDVVLAIMNVLYTEFGDTKYRPHPLLAKMVRANQLGRKTKIGF
                     YDYNK"
     gene            34373..35548
                     /locus_tag="KRH23_001652"
     CDS             34373..35548
                     /locus_tag="KRH23_001652"
                     /EC_number="2.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003985 - acetyl-CoA C-acetyltransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="HHS5224933.1"
                     /translation="MREVVIASAARTAVGSFGGAFKSVSAVELGVTAAKEAIKRANIT
                     PDMIDESLLGGVLTAGLGQNIARQIALGAGIPVEKPAMTINIVCGSGLRSVSMASQLI
                     ALGDADIMLVGGAENMSMSPYLVPSARYGARMGDAAFVDSMIKDGLSDIFNNYHMGIT
                     AENIAEQWNITREEQDELALASQNKAEKAQAEGKFDEEIVPVVIKGRKGDTVVDKDEY
                     IKPGTTMEKLAKLRPAFKKDGTVTAGNASGINDGAAMLVVMAKEKAEELGIEPLATIV
                     SYGTAGVDPKIMGYGPVPATKKALEAANMTIEDIDLVEANEAFAAQSVAVIRDLNIDM
                     NKVNVNGGAIAIGHPIGCSGARILTTLLYEMKRRDAKTGLATLCIGGGMGTTLIVKR"
     gene            35743..36645
                     /locus_tag="KRH23_001653"
     CDS             35743..36645
                     /locus_tag="KRH23_001653"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HHS5224934.1"
                     /translation="MFKKENQRYNLISYTNEEEMTLKEVLLDKLNFSVRSLSKMKREK
                     SVLVNGVYKKPSLKVYSGDLIEVKIDEEKANFEPQDLNLQIIYDDFDIIMVNKPPFMV
                     VHPTKSHYDKTIANGISYYIDNQKENVKIRFVNRLDMNTSGLVIVAKNAYAHHTLSTA
                     MSENKVEKKYITVVDGIIKENEGTIDEPIYRPTEDSIKRIIDERGQSSVTHYKVIERL
                     ENATVLEVSLETGRTHQIRVHMAHIGHGIIGDELYGYVDEELINRQALHAYKLEFEQP
                     RTKEKLKFKADIPEDMKELISKLR"
     gene            36659..37663
                     /locus_tag="KRH23_001654"
     CDS             36659..37663
                     /locus_tag="KRH23_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HHS5224935.1"
                     /translation="MIIHKFIIHVLDKNSDVPILNDFEGKVNQEVDGFFQKAIKRIAK
                     DEDLRKGVFKDYNDNLIKNCCEQIIYDESTFLKNSKEIASYLFDVMKINAALESCDLA
                     ICLYTIKDEKSVAILKLDYKKLYTHSIEFVDDKFNIQMVSNEIGIPETLRQKQGALIS
                     LSGINDEFHLRLLDKDAEKEGSESKFVTEFLNAKKIDDDKYKTKVFKNTAENWITNAL
                     SNDIKQAEDVRSILNYTLKEKHEVDINDFVDNSIKDDELKDSFKEHMEEKGLDESFSI
                     DKKWVEKKLKKRSIKTDNGFDIKGNLTDFEDPMKYTVKQNQDGTIDIIIKNVTFYEEK
                     "
     gene            complement(37807..38034)
                     /gene="acpP"
                     /locus_tag="KRH23_001655"
     CDS             complement(37807..38034)
                     /gene="acpP"
                     /locus_tag="KRH23_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000036 - acyl carrier activity [Evidence
                     IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HHS5224936.1"
                     /translation="MFEKIKEIIAEQLGVDNLDEITMEASLMDDLEADSLDAVEIIMA
                     LEDEFGIEIPDEEAENFKCIGDICKYIEENK"
     gene            38206..38631
                     /locus_tag="KRH23_001656"
     CDS             38206..38631
                     /locus_tag="KRH23_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224937.1"
                     /translation="MKYVGLLLTSVGMFLLIAVNFYYNSITLDMQRIEDYVMETNLIL
                     EDVAEKESYVSNEKEDYISRLMHVKKGIENSKTSFLIERYKEYKIKSIESLIYTISEE
                     KKDYLDEVDRYNKLGEKEINKLINKNFLEVTYLSITTYI"
     gene            38679..38885
                     /locus_tag="KRH23_001657"
     CDS             38679..38885
                     /locus_tag="KRH23_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224938.1"
                     /translation="MTKLEDNMERFFGGCEGFFGNKMLIIIVIVFLLLCTDILEDLLC
                     DDNIWIWVILIVLLLFNFDDGCCC"
     gene            39067..39246
                     /locus_tag="KRH23_001658"
     CDS             39067..39246
                     /locus_tag="KRH23_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224939.1"
                     /translation="MLDRFFGEEGCFGGGGWWIIVLFFLFLAFGDSWAEFDIMAWIPF
                     LIVLLILCCCGGCLE"
     gene            39280..39480
                     /locus_tag="KRH23_001659"
     CDS             39280..39480
                     /locus_tag="KRH23_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224940.1"
                     /translation="MLDRFFGEEGCFGGGGWWIIVLFFLFLAFEDCWRDIDIMSWIPF
                     LILLLITCSCGGFFDGEVGCGC"
     gene            39727..40749
                     /gene="ccpA"
                     /locus_tag="KRH23_001660"
     CDS             39727..40749
                     /gene="ccpA"
                     /locus_tag="KRH23_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator CcpA"
                     /protein_id="HHS5224941.1"
                     /translation="MKMKGNITIKDVAKQAGVSISTVSRVINDSKPVTDEVKQKVLEV
                     IKETGYIPNPLARSLVTKKSQLIGVIVPEVSDSFVNEVLNGIEEVAKMYDYDILLANT
                     YSDKEQELKSINLLRAKQVEGIVMISWIVEQEHINYIQNCGIPATYISKTARNYDIYT
                     VSTSNEEATFDMTEHLIKKGHEKIAFIMTSKDDTVLEMERLAGYEKALSNNNIELDKS
                     LIKYGGTDYESGYNSMKELLDDGIIPHAAFVTGDEAAIGAINAICDAGYKVPEDISVA
                     GFNDVKIARMYRPKLTTVYQPLYDMGAVAIRMVIKLINKELIENKKIELPYRIVDRES
                     VTERKK"
     gene            complement(40872..41270)
                     /locus_tag="KRH23_001661"
     CDS             complement(40872..41270)
                     /locus_tag="KRH23_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224942.1"
                     /translation="MKKLDTESLEKMAKQKNIDKDKIEKMADSYKGKSENELMEELIK
                     IGKNLDGRDEVVSKFKAFLDENQRKKLDNIMEKISDAENQRDTKPAKTKKAKPTKGKS
                     NSPVPKNTPGSQQKKSKSLFKKTKKSNPHE"
     gene            41482..42390
                     /locus_tag="KRH23_001662"
     CDS             41482..42390
                     /locus_tag="KRH23_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224943.1"
                     /translation="MNNLLFLIGVIALSNGNISIFDDKNKSKGNNRVRKNKKNANDKL
                     SQSTHGNLRFDANDIKRGLRLMDLSEEDLEMGMEIITRTKKYMSRDERKILIKIESVL
                     DLVRGIKKLNNIDMVDTEDETDFFRKMDSDDKKNMMIKEIIDVFPEKRKNSVEKAIGM
                     KKKIDLFAELFLPDDFGEGGFSLSSLANINNLGSMNNLKLLGSLLRGDDSNNDDEDNN
                     DELNYEDEELDCEDKELDYDDELTDEGEMEDNEDELVEDKNTGYENIENDEDIVYDEE
                     LYNINEQESEYNYNEKNTKTRAKKKR"
     gene            42505..42685
                     /gene="ssrS"
                     /locus_tag="KRH23_001663"
     ncRNA           42505..42685
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="KRH23_001663"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            42868..44085
                     /gene="cdeC"
                     /locus_tag="KRH23_001664"
     CDS             42868..44085
                     /gene="cdeC"
                     /locus_tag="KRH23_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exosporium morphogenetic protein CdeC"
                     /protein_id="HHS5224944.1"
                     /translation="MQDYKKNKRRMMNQPMSTMNEEEVYTDEINSEDMRGFKKSHHHN
                     GCNTDNKCECHDDCNPCNPCNPCKPNPCNPCKPNPCDDNCGCHDNCKCDCEPCEMDSD
                     ECFENKCGPECCNPISPRNFSVSNAVPFAIEANRIFDTMQFQTFTDATGPNGEPLTFE
                     TEVVEVFGSVPSAGQASVTIEKICLSNDGIVIDTGMTTLEDFDLDPLGDIVGRNCETT
                     FEFAVCGERNAECCRQGKGKSVAYKQRGLTVAVRNLVLELRGRCGCTEFVALAFPAVR
                     AGGGCKRRVDYVEFTFNTLSAPICLPADGRAVTLRQEYQTNLTVDCIGKSILKLECNE
                     CCEPFYELIIPNDIDLVLCLQETVSTLISEQIVVLASPNPIQPRLVDTFSKVCDFSQC
                     GPNHGSGKPSCHR"
     gene            complement(44186..45508)
                     /locus_tag="KRH23_001665"
     CDS             complement(44186..45508)
                     /locus_tag="KRH23_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HHS5224945.1"
                     /translation="MKVPYLVLSTVILFISNFIVRIFGFLYKIFLSRALGETGLGIYH
                     MIFNFLMICLAVTTTGIPTALSCLVAKRKALNDRHNTNALFISTLYISFFVALIISIV
                     ASFNSSFLSLKFLKDAKLNLFILAVCPAIVIITLSNVLRGYYYGIKNVKIPAIGQIIE
                     QIGKILFVFLLVMYINNKSMNCYIALLGISIGELSNIIFMLICLWRDSSFDNRYIISI
                     KDFYNSSMETLKMSIPITCNRMSNILLQSISSMMIPSRLALSGMTYQQSLSMYGIVSG
                     MVMPFIFLPFTVGSALIVNLIPTISQEMALRKRKSVIKKIKYSILLTLFVGILSSIFF
                     YFFGKDLCILVFKNTLAGEYLKAMFLVPLFMSLNQTLSGILHSIRKELASSINTITGM
                     LIQLIALYVFLPIPGLNIYAYIYTMTIVSIFTCLLHTIVLFKSLKSIR"
     gene            complement(45559..46353)
                     /locus_tag="KRH23_001666"
     CDS             complement(45559..46353)
                     /locus_tag="KRH23_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004401 - histidinol-phosphatase activity
                     [Evidence IEA];
                     GO_process: GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphatase HisJ family protein"
                     /protein_id="HHS5224946.1"
                     /translation="MFYDYHMHSSFSTDGKSTMEEMVKKSIELGLEEICFTDHVDYDV
                     YADDSFSIVYEDYFKSLETLQSKYKDKISIKKGIEFGVQTQLMDTYKKEAHQYPLDFI
                     ICSIHAIDTMDLYLGNYFKDKTQHEVYENYYLYLYNIVKNYKDYSILGHLDLIKRYAP
                     YDTILDDRLFSDIIEETLKQAIYDGKGIEINTSCYRYNLPDLTPSKYILQMYKDLGGE
                     IITTGSDSHHISQVACEFDYIYSLLKNMGFKYVSKFNKLKPEFIKL"
     gene            46463..47908
                     /locus_tag="KRH23_001667"
     CDS             46463..47908
                     /locus_tag="KRH23_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HHS5224947.1"
                     /translation="MEKYRIDLNEKKSTKYIQIFNHIKELIINKELVEHEKLPPIRKL
                     SNFLQVNNTTIVKVYELLENEGYVYKIIGSGTFVSSLNSYKSGIDNRKNKIIVQREDL
                     IHFDNGNPSNDMFPIDSFKNAVNMALSKDGSSIFEYDEGLGSEELREKMVEYLSDGNI
                     KTTKENIQIISGAQQGIDIVCKGLISYSDVVFMEEPSYNGAIEVFKSRGAKIISIPML
                     DDGIDIGILKLKLEKIKPRLIYIMPNFQNPTGISYSTYKKKKLIELAEEHDFYIIEDD
                     FISDFVFESKDNRTIRSYDDKNRVVYIKSFSKILMPGLRIGIVEMPNELLKKVLWAKY
                     SSDISTPGLIQKSMYYYMNNFDWKNYLSHIEKIYTDKYKLAKNLINDKLSGKLKVRKS
                     CGGINFFLELPRGYTSQAFTNFMLNKGVSMLPGTYFFDNLVDDRFFRINIARPSMEEL
                     EKGISIISDNIDEFFCEYKNKLDIKSNKLFY"
     gene            47937..48146
                     /locus_tag="KRH23_001668"
     CDS             47937..48146
                     /locus_tag="KRH23_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 domain-containing protein"
                     /protein_id="HHS5224948.1"
                     /translation="MFDKKKLDRINELAKKNKEGILSADEIKEREILRKEYLENFRAH
                     FRSRLDSVKVVSPEEYEQYMKNNKN"
     gene            48166..49560
                     /locus_tag="KRH23_001669"
     CDS             48166..49560
                     /locus_tag="KRH23_001669"
                     /EC_number="3.4.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004177 - aminopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HHS5224949.1"
                     /translation="MNLKYEFKNAWDFERKENTIEQIMQYSRNYMEFLSKSKTERLSV
                     KEIIKLAKENNYISIDEAMEKGSISCGDKIYVINKEKAVALFVIGKNYIEKGMKIIGS
                     HIDSPRLDLKPNPLYQESNLGFFKTHYYGGIKKYQWTAIPLALHGIVILNDGTKVDIS
                     IGEEDSDPVFCVTDLLIHLAGDQMQKKLSEGISGEALNILIGNIPLEDEEKEPITANI
                     LKILNEKYNIVEEDLLSAEIEVVPAGKARDLGLDRSMVLGYGHDDRVCSYAAVKAILE
                     TEQPEFTSVALCVDKEEIGSKGNTGMHSKFFENTVAELIALEGDYCDIKVRRALANSK
                     VLSADVSAGYDPNFGEAYEKRNSAYMGNGVVLTKYTGSRGKSGCNDANAEFMSEVKRI
                     FNKGNVVWQTAELGKVDQGGGGTIAHILANQGAEVIDCGVGVLNMHAPHEIVSKVDIY
                     EMYKGYKAFFNINL"
     gene            49800..50015
                     /locus_tag="KRH23_001670"
     CDS             49800..50015
                     /locus_tag="KRH23_001670"
                     /inference="COORDINATES: protein motif:HMM:NF012610.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HHS5224950.1"
                     /translation="MDEKRQKKEMDLEVNSFVPLYQQLYDNIKKQIASGIYKPGDKLP
                     SEGDLCKEFNISRITVRNTTFLYKIAK"
     gene            complement(50094..51260)
                     /locus_tag="KRH23_001671"
     CDS             complement(50094..51260)
                     /locus_tag="KRH23_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HHS5224951.1"
                     /translation="MKGGVRKRGKKWYYYFDAGIVDGKRKKVERVGGNTKKEAEKSLR
                     DAINEYENAGIVFDETNMSLSDYLNFWYKEYVLLNCKYNTQESYRNLIENHIEPRLGK
                     CKLKSINPAIIQEFLNNKSKETYTQNGEEKHYTKGVLKAIYVVLNAALKSAVYPYKLI
                     KENPVQYASIPKNVLKVKNESDNKTITLDEFNKILEIYPKNTNIYIPLLIGFHTGMRK
                     GEILGLCWDNVDLDNNIIKVRKNLIKRKVSEFELASPKTKTSIRDIKIGDTLSRILKE
                     EKLNQKKQKIKIGKWYKETEYDWVCRKKDGSFVNHNNIDAAIRTINKKLNINFNFHCL
                     RHTHATLLLENGANVKYIQQRLGHSQLSTTMDTYSHVTSKMESETIDILEGILQ"
     gene            complement(51398..51613)
                     /locus_tag="KRH23_001672"
     CDS             complement(51398..51613)
                     /locus_tag="KRH23_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224952.1"
                     /translation="MNKLNLSFNKKKKFELSKEELELIENWLGNKYAGDMTIPAIVDF
                     SLETDIEYEKIVVYLAEKVLESRDKKH"
     gene            complement(51663..51884)
                     /locus_tag="KRH23_001673"
     CDS             complement(51663..51884)
                     /locus_tag="KRH23_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHS5224953.1"
                     /translation="MLKELRKKKKLTQIELAKRVGCHRSQISRLENNENKDLTIPALI
                     ELEIALGLEEKYLVNYFADEYIKKRKLHK"
     gene            52168..52305
                     /locus_tag="KRH23_001674"
     CDS             52168..52305
                     /locus_tag="KRH23_001674"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224954.1"
                     /translation="MNKTKYYDILKLNLLMKKLKELDKNKINEYKIKVKEIHKINKKE
                     E"
     gene            complement(52342..52737)
                     /locus_tag="KRH23_001675"
     CDS             complement(52342..52737)
                     /locus_tag="KRH23_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHS5224955.1"
                     /translation="MNRIKELREEKGISLDKLSEDLHINKSTLSRIENGLREPKKSTI
                     EEYANYFDVSTDYLLGRTDVRNSLFINKNEKDYDAENFKTEKELIENMYLDEDMKEVF
                     NIFSELSPDAREKALKVAELFLLDEKNKK"
     gene            52916..53149
                     /locus_tag="KRH23_001676"
     CDS             52916..53149
                     /locus_tag="KRH23_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF739 family protein"
                     /protein_id="HHS5224956.1"
                     /translation="MYLNRLEGLMKENRHTQKNVADILGLSSYGFRLKLKGKNEFKAS
                     EIKKISKLYNVSADYFFSDEVAKIAIKEERGNK"
     gene            53149..53937
                     /locus_tag="KRH23_001677"
     CDS             53149..53937
                     /locus_tag="KRH23_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage regulatory protein"
                     /protein_id="HHS5224957.1"
                     /translation="MKNLTIIKQNNQFLVESREVAELIEKKHDNLLRDIRGYKKILED
                     SSNLKSQDFFIESTYINTQNKIQPCYLLTKKGCDMVANKMTGEKGIIFTAIYVTKFEE
                     MERELKEQQPKLPTTYKEALQQLLIEVEEKEQLQLENQEKDKVIQLQQPKVLFADSVA
                     SSDNSILIGELAKLLRQNGIDTGQNRLFDWLRNNGYLIKRKGEDYNTPTQKSVDLGVI
                     ETKEGTRVHPDGHTSITKTPKITGKGQIYFINKFKKNNQISMLG"
     gene            53994..54131
                     /locus_tag="KRH23_001678"
     CDS             53994..54131
                     /locus_tag="KRH23_001678"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224958.1"
                     /translation="MSNKKKYTLSITEELYNKCKEKANQKGMSVNEYILLVISKNLKN
                     I"
     gene            complement(54143..54310)
                     /locus_tag="KRH23_001679"
     CDS             complement(54143..54310)
                     /locus_tag="KRH23_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Arc family DNA-binding protein"
                     /protein_id="HHS5224959.1"
                     /translation="MPSKLPRYTLRIDNNLLEKIKYIAESEGRSANKEIEQLIKKHVE
                     SYEKINGKINV"
     gene            54433..54609
                     /locus_tag="KRH23_001680"
     CDS             54433..54609
                     /locus_tag="KRH23_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin-antitoxin system HicB family antitoxin"
                     /protein_id="HHS5224960.1"
                     /translation="MTAKKRVTVRMPDELNEELHRQSQRKGLSKNAFIINILWKEFED
                     LQDLKDEQEVDKYE"
     gene            54602..55240
                     /locus_tag="KRH23_001681"
     CDS             54602..55240
                     /locus_tag="KRH23_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BRO-N domain-containing protein"
                     /protein_id="HHS5224961.1"
                     /translation="MNNLQIFEKMEFGQIRMAEIDNKPYFVGKDIAKSLGYKNTNDAI
                     LRHCKGVVKHEGFKINGIKIALITEGDVYRLIVGSNLPNAEKFESWVFDEVLPTIRQT
                     GQYQAQQNVITELTGTIGDLKGTIKEYKKLCKITCSKKQQYSKYIKNRLDIDKANKEY
                     NQVKARLFLILGVEKWEDIDFDTSNNLIQIIDDCIKVIKSERPYKQLSYFEN"
     gene            55299..55679
                     /locus_tag="KRH23_001682"
     CDS             55299..55679
                     /locus_tag="KRH23_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224962.1"
                     /translation="MKNNTSDSRVKYFCKCPYCGFDNEVEVKKGLKPKICCICTKEVE
                     YEKLEQQSALENTEIKGVCNQMKIKKLALATGEVFENIELKEFENKGECLPSNMVKVI
                     DGKQELLINKEFILSLEVKRKTTF"
     gene            complement(55669..55821)
                     /locus_tag="KRH23_001683"
     CDS             complement(55669..55821)
                     /locus_tag="KRH23_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224963.1"
                     /translation="MVIPIAKNTKQTSKTVASKASKILKDGRYSAASKSVAGSALSQT
                     KKGPKK"
     gene            55880..56077
                     /locus_tag="KRH23_001684"
     CDS             55880..56077
                     /locus_tag="KRH23_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHS5224964.1"
                     /translation="MAINDNINKILKDRDLKAWKLAKEIGVDSGNLYAILRGENKNPT
                     IDTLIKIADYLDITLDELVGR"
     gene            56107..56550
                     /locus_tag="KRH23_001685"
     CDS             56107..56550
                     /locus_tag="KRH23_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHS5224965.1"
                     /translation="MSKLGNISNFNLDKQEDKSFNDLDNISICFSEGIRKVVEMNLNN
                     YKNKISKYLNETSKIELLEPKELTIVISKGYPDYLMSVEEASKRLKIDKVFGYELIKN
                     GLLKSVDIGATKVSSYELDDFITRNQGKNIKEMLREMKELREGVI"
     gene            56678..56866
                     /locus_tag="KRH23_001686"
     CDS             56678..56866
                     /locus_tag="KRH23_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224966.1"
                     /translation="MKIIYKNKVYKVEQDKKLFRITYYDEQRGSKKFNKEKKIKRSVL
                     TRDIELVNLYLPAHLKIK"
     gene            complement(57001..57171)
                     /locus_tag="KRH23_001687"
     CDS             complement(57001..57171)
                     /locus_tag="KRH23_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224967.1"
                     /translation="MSNKDIYTREEDKRFTLRINKLLFEKIEQLAQKDKRSIGREIEF
                     ILEKYFEDNPLE"
     gene            57314..57472
                     /locus_tag="KRH23_001688"
     CDS             57314..57472
                     /locus_tag="KRH23_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Arc family DNA-binding protein"
                     /protein_id="HHS5224968.1"
                     /translation="MTNERVRFTFRLPAPLLEKIKNRASIEGSSMNSLILHILWDYIK
                     EIENKEVK"
     gene            57472..57699
                     /locus_tag="KRH23_001689"
     CDS             57472..57699
                     /locus_tag="KRH23_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224969.1"
                     /translation="MVELVKEFDLQTIKVGNAVKVNCKRFGFEIDCIVVVATEKELNL
                     AYFDEGRGCMEYQALITEDIQDGDYEIKILS"
     gene            57797..58111
                     /locus_tag="KRH23_001690"
     CDS             57797..58111
                     /locus_tag="KRH23_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224970.1"
                     /translation="MESLKRIKKMVQKQLVLAELEINKNSKLYEELENKDRGLIDDIH
                     MREYLREKVAWERVKYAIENILGGINLEIKSKEHEESEDYKIFQLILEELERDKPIDV
                     QI"
     gene            58195..58704
                     /locus_tag="KRH23_001691"
     CDS             58195..58704
                     /locus_tag="KRH23_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siphovirus Gp157 family protein"
                     /protein_id="HHS5224971.1"
                     /translation="MSTLYELTTDLLEIEEGLTETTGNETEKLEEIKEIIKQEIQNKN
                     TRIVSVILNIDSDINSIDSEIKRLQELKRVKKNTLDRLKSNIKDCMELLGTKKVETVL
                     GNISIRKSAGSLVIEDEEKIPAIYKTVEQVVKVDKNIIKDFIKKGHEVEGCRIEYGTT
                     LTIPKAKKE"
BASE COUNT        23977 a         6161 c        10230 g        18377 t
ORIGIN      
        1 tgtttgggaa ctacaaggga taacaataaa cagcaaaaat aatcctaaaa ctttaaataa
       61 acaagaacta gaaaagatgg gattaaattt aaaagactat aatgtaacac aggaatgtat
      121 aattgaagac ataacttcta gaaaagatgt aaataaatat ttgagaaaaa cttcttcacc
      181 tattacagaa cttacaggaa gtgatagata tgaaacagca gttaaaataa gtaaagaggg
      241 ctggaaaaat ggttcagata aagtagttat aataaatgga gatgtaagta tagatggcat
      301 tatatcaact ccactggcaa ccacatataa tgcaccaata cttttggttg aaaaaaacaa
      361 tgtacctaat agtgtaaaat cagaattaaa gcgtctaaac cctaaagata taattataat
      421 tggagatgag aatgctattt ctaaaactac tgctaatcaa attaaatcaa ctgtaaatgc
      481 tagtcaaaca cgtttaaatg gttctaatag atatgagaca tctttattga tagcaaagga
      541 aatagataaa aatcatgatg tggaaaaagt atacataaca aatgctaatg gcggagaagt
      601 ggatgcactt actatagcag caaaagcagg tcaagacaag caaccaatta tattaactga
      661 taaagatagt attacagaca atacatataa atggttaaag agtgaggatt tacaaaatgc
      721 ttattttata ggtggtcctc aaatgatatc aacaaatgtt ataaataagg taaatggaat
      781 aactaaggat agtgttacta ataatagagt atacggagca gatagacacg aaacaaatgc
      841 aaacgtaata aaaaaattct atacagatga tgagctagag gctgttttag tagctaaatc
      901 agatgtactt gttgatgctt tagcagcagg tccattagct gccaacttaa aatctccaat
      961 acttataaca ccaaagacgt atgtatctgc ataccataaa gaaaacttag aagctaaatc
     1021 agctaataaa gtatacaaaa taggaggagg attgacttct aaggtaatga gctctatagc
     1081 atcatcatta tctaaacaca atacgactcc aacagaacca ggaaatagtg ggggtaagac
     1141 agttatgatt gacccagggc atggtggttc agcacctgga aattcatctg gaggaatgat
     1201 tgaaaaagat tacaatttaa atacttcact tgcaacaact gaatatttac gttcaaaggg
     1261 attcaatgta ataatgacaa gagacacaga taagacttta tctcttggaa atagaactga
     1321 tctatctaat tcattgaaac cagatttatt tacaagtata cattataatg gctcaactaa
     1381 taaacaaggt catggtgtag aagtatttta taagcttaaa gataaaaatg gagggactac
     1441 taaaactgta gctaccaata tattaaatag aattttagag aaatttaaac ttacaaatag
     1501 aggtataaaa acaagagtac ttcctagtga ttctacaaaa gattatttat acgttttaag
     1561 aagtaatgat atgccagctg tacttgtaga atgtgcattt ttggataatg aaaatgatat
     1621 gagtttaata aactcatctg caaaagtaaa agaaatgggt acacaaatag gtaaaggaat
     1681 agaagattca ttaaaataaa tggaaataaa aatatttaaa aacttaatgt aaatttatag
     1741 ttgtaaattt atactaaagt caaaaaatga aatataagtg tatcaatagt aagactgtat
     1801 gtacatttgc acatgtgaat gcaagtatat atacagtctt tttttgtagt taaatgcaat
     1861 aatttgattg tgttttgtaa aatacacaat atgatataat tagataatat acacttaatt
     1921 taattgagga aggtgattat atggaatatt tatttgaaaa aagtagttta aaagaatatg
     1981 gaaatgaagc tttagataaa tatagagaat tattagataa aactgataat aattcaaggt
     2041 gtattctttt gttagtacca aacaataaca caaagatacg atatgaaagg gctctaagat
     2101 taaattatag tgaagaactg aaaataacaa catatataag ttttgtgaag aaagaattag
     2161 ttaaatactg gccactaata atagaaaaat gtgatgaaat aagtacaaag gctgtatctc
     2221 caacatttat atcaaatagt ttaagtgaat atttaatagt gcaaaaagtt aaggaaaaaa
     2281 ggatacaaga aggatatttt gaagatatta caggaaccaa taaatccata gcaaatagta
     2341 taatgactaa cataaataag tctgcattta atttaattga ttttgatttt attggagaaa
     2401 aaatatattc atcaaagaaa aataaagata gtatatatag attttcatac actcaaatgg
     2461 atgaaattat atcatattat ataaattcct tattatcaaa ttcaatttta gataatgcat
     2521 taagcatata tttatacaat caatacctac ttaatgatga tttttattta aaaaacttat
     2581 ttacagaagt gagatatata attgtggata gccttgaaag ctcaagtaat gcagaagttg
     2641 attttataac agaagcattg gataatacat tacaaagtta tatatatttt gattatagta
     2701 gggattattc tgtatttaat aatgtggata tagactatat aaatgagaaa ataatatcaa
     2761 aaattaagcc caaagaagaa aatattaaaa agaaggagat tagaatagaa gatttatact
     2821 tattacctgc aaatatagaa ttaaatcaat caagtcaatt atacaatgaa atgttagatt
     2881 taataagtga aaaagttaca tctcttatag aagaagatgt atctccaaga gatatagcaa
     2941 ttatatctcc tataaacaat agtatattgg agcatcaaat tagagattct ttgatagaaa
     3001 aaaatataga tgtttttagt actaagaagg ataaaaaagc tgtggattat ccatatggga
     3061 atgcattggt agtggctaca tgtatatttt atggatattt agattttata aaagatgatg
     3121 aatacttaag ctttttagaa actcttttag aaataaatag gataaaagca tttaagattt
     3181 ttaatgaaac aagacattta agtattgata atatagatga acatagtcag tatcgtgata
     3241 ttttacagta tattgaagaa aaaaagaaga gtgatataaa aatacatgaa tttttaactc
     3301 aattttacat agataaaatg ttaaatttaa aagaaggtaa aaagaatgtt gggttatgta
     3361 aaaagataat agctgaaagt gagtctttta gtgaaagttt aagtctactt gggatgaaaa
     3421 aagaaaagat atttgtagaa gctttaaaaa gtacaataaa cgattattac tctgttgtcg
     3481 atatagaaga gttgaaatcc aaagacaaaa tagtaataac tactccttat tcatatatat
     3541 catcaaatat agatagaagt atacaaatat gggtagatat aggaagtaat gcttggaata
     3601 tgaaaataga aaaagatata agtaatttaa ttgtacttag aaaatctttt gaagaaaaaa
     3661 agatttatac aaatgaaatg gaagaatatt ataaaaaata ttatctatac aatacagtat
     3721 ataatttgtt attaaatgca aagaaaatct atgcatttaa aagtgaatat gcgattaatg
     3781 gttatatcca agagagtata ttatatagta tacttttaaa aatctcacat aaaggagata
     3841 aaaattatga ttaatataaa ttatagagaa gaccagatac caataataaa ttacgataat
     3901 ggtactatgg cagtaccagc agtaccaggt gctggaaaaa catttataat aacaaatttg
     3961 gtagctaaac tattacttga gcagaaacat aagggtggta aaatattaat tcttacatat
     4021 atgaatagtg ctgtaaataa ttttaaaggt agaataagaa agattcttga agagaataaa
     4081 atagatgata ctaattcgta tgaagtaatg actatacaca gtttggctgt aaaaataata
     4141 aaggaaaagc cagaagttgt aatgttaagt gaggatttta acatagctga cgatttgcaa
     4201 aaaagtatta tattaaatga atgtataagt agatttagat ttgaaggtgg agaaagagct
     4261 tttagatggt ttttaaagga gcaaaaagat gaacgctgga aagaaataac tcttgaagcc
     4321 tgggaaagag gtttttttga atttgcagga aatgcaataa gtgaacttaa gtataaggga
     4381 atttctccag ataaccttga agaaatattg tcaagaggac acaaaggaat gcttaaaatt
     4441 attttaccaa tatataaatt gtatgataga aaattaaagc aaaatggatt gctagattat
     4501 gatgatatat taattttagc agaaaaaact ttaagcttag acgaagggct tagaaagaag
     4561 tttcaaacta gatacaaata tatatttgaa gatgagtgtc aggactcaaa tgaaattcaa
     4621 ggtaatataa taaaaattat atctagcgaa aataaaaacc tagttagagt tggagatata
     4681 aatcagagta taacaggaac attttcatca tcagacccta aattttttaa agaatttata
     4741 aatagtgcag atttctgtta taggatggat atgtcaaatc gaagttcaaa agatatactt
     4801 gatttagcaa acactcttgt caagtatgtt acaaaggaat ttagacaaga agaatgtaga
     4861 catgctcttg aagatatgca aataaaaact gtgccaaatg gaatgggata taaagaaaat
     4921 cctaatccag aacattataa tataaatgta aagtggtatg agagttggaa aattgaaata
     4981 gagcaaactg ctagatacgt taagggtata aaaaataaat atccagataa aagtataggt
     5041 atattggttc catttaatga acaagtgaca caagttgcta aagaacttag agagaataat
     5101 ctaacctttg aagaattagg accaaattct ttgaataaaa ggaaggttat aaacaacata
     5161 gcatatatta ttgattttat gttacattgt gatgatgtag aaaagttaat agttgtactt
     5221 aataaagttt ttatagatac tgataatgaa gaagaaataa agtatttttt agaagaatta
     5281 aaaaactatt ctactgaaga aattatttat aattttgaat ttagtaagtt agataatgat
     5341 ttaatagaat ttaaagaaga aagtgatata tacttaagtt ttaaaagagg aatagatatt
     5401 ataaaacaga tattagaata tccaataata aggttagacc tcttagtttt gtttattggg
     5461 aaaaaactta atttagaaaa agaagataaa gctgtactgg attatatatc tttttatata
     5521 aagtatctag tatcagaaaa tataaatatg gatttagaag atgtatataa tttattgttt
     5581 gatgtaaaga acagggtgtt taatcatata atagatgtgg tatatgagat aaatggatat
     5641 gaaccagagc ccggtagtat aacactatgt aactatcata aatcaaaggg gatggaatgg
     5701 gattgtgtgt ttttactagg tcttgttgaa tataatttcc ctgacaatat taatcaaaag
     5761 tttcagagtg ataaatggta tctaaaagaa aaatataaaa accctatggc aattattaaa
     5821 tcagaagttg aagctatatt aaaaggaagt atttcaacag attatgctca taaaacgaag
     5881 attgattcta taaatgaaaa gattagactt ttatatgtag ggattactag agcaaaggaa
     5941 atgttagtac tttcaggaag tgcttataga gatgaaagtg atatagggaa taagagaaaa
     6001 gagcaaaaac catgtatata tttaagcaga cttaatcaac atattattga aaaaaggtca
     6061 aattaatata taataagtta ttaaaagatt gcttgaaata tatctaaaag gggataaaac
     6121 aatatgtaca gtaagtaact actaaaaaat aaagttaaga gagaagtgat atgagtgaac
     6181 gataaattaa aatatttttc ttatagtcaa aattcaatta acacatataa atcatgtcca
     6241 ttgaaattta aatataaata tattgataga ataaattgga aaaatgatga tgttggtagt
     6301 agagagtatt atgaaacttt aaaaacagga agagattttc atttgatttg tgaaagatat
     6361 tttagcaata tacctcttgg aatctatttt aatgaggatg ataaaaatag taaaaagttt
     6421 ttaaagtgga tggaaaatat aaaaaaagtt gttcctattg aaaaaggaaa aacgtatttg
     6481 ccagaatatg aagtaaggat gacattaaat ggggatataa tacaggcaaa gtatgattta
     6541 gttgtaattg gaaataacaa tatagaaata tgggattgga aaaccgagtc taaaaagatt
     6601 gactataaac acgtagaaaa tagaatacaa actattgttt atatgttttt agcaaaagaa
     6661 gtaataccta aagttttaaa aatggacata aatgttaaag atataaatat gagatattat
     6721 caacctgaat ttgatgactt accaattacc attttatatg atgaagaaaa acatgaagca
     6781 aatagaaata aaattcaaaa ttatataagt atgataaaaa acactaatta tgaagaacat
     6841 acatacgaag acaatctata caatgatata gaaaaggtat ataataaaga agaacgtatg
     6901 tgctatagaa ataaaaagca ttgcaagtat tgtgaattta ataagttatg taatggcaaa
     6961 gaaatagatt atagtatttt ggaggcggaa atttatggga cttaggtttg tattaggtag
     7021 aagtggaagt ggaaaatcca cctatatact agatgagatt aaaaaagaag ctcaaaaaaa
     7081 tgaaacgaca tcaattatac ttttagttcc agaacagtac acatttgagg ctgaaaatag
     7141 agtaagtaag ctattcttag gaaaagaaaa agataagtat ctaagagtta gggtacttag
     7201 ctttaagaca ctaagtaata tagttttttc tcaagtagga ggattgacag atgtaaatat
     7261 aaattctagt ggaaaagcaa tgatggtata tagagctatt gaagatgtaa gtgaagaatt
     7321 aaatgtgttt tcaaaatcaa aatcgcagtc tggttttgta agttcaatta cagatatgat
     7381 atcagaaatg aaacaataca atataagccc tgaaatgtta gaaaatatat ctggagaatt
     7441 ggataatgaa actttaagtt taaaattaaa agatataagt aaaatatata attcttttga
     7501 agggaaattg catgaaaatt atgtagatgc tcaagatatg ttaacttcat tggcaagtaa
     7561 aattgaatta agcagttatt tagatggagc ttgtgtttat atagatgaat ttacaggttt
     7621 tacaccaaat cagtacaatg tcataaagag tatattaaat aagtctaaaa gtgttaatat
     7681 ctctttgact gtagatgata tcaactatat tgggtacagt aaatctgata tgttttctag
     7741 aacgaaattt acttattcaa aattgactca attgtgcaac gaagaaggca taaaaatatt
     7801 gccacaagta aatttaaaca caggtgttat aaaaagattt gaaaaagtta aggaattaca
     7861 gcacttagaa agattttata atgcttatcc atataaaata tattcaaatc caactgaaaa
     7921 tataaagata aaagagttta acaatttata ttcagaggtg gaagagatag ccagagaaat
     7981 tgtacattta gttagagata agaatgtcag atatagagat ataaccattg ctacaagaga
     8041 tttaaataga tatgattttt tagtacactc tatatttaat gaatataata taccaaactt
     8101 tatagataag aagagagagg caaaaagtaa tccaatagtt attttaatta tttcagcttt
     8161 agaaatgaag aatagacgat atgggtatga aactatgttt aggtatttaa aaagtggact
     8221 tataggaatt gataatgatg atataaattt actagaaaat tatgtgttgg ctaatgggat
     8281 taaaggtaaa aaatggtttg atgaaaaatg ggattataga ataactcaaa gtctttcagg
     8341 tcaagaaagt gaatttgaac tggaattaaa agagaaaata aatgaaataa aaaatagagt
     8401 attagagcct atagtaattt tacaagaaaa attaagagga aaaaatagag taaaagaaat
     8461 ctgtagatat atatatgaat ttttattaga tataaatatg ccagaaacta tagaaagttt
     8521 aatagtaaat tttaaggata aaggggaact tgatgttgca aatcaatact cacaagtttg
     8581 ggacatagta gtggacatat tagaccaaat ggtggaactt atgggtgatg aaataatttc
     8641 tttagaaaaa tttataaaat taataacctt aggttttgat gaatatgaat taggactggt
     8701 tcctcctagt atagaccagg tacttgtaag tagtgtggat agaatgaaaa atccagacac
     8761 gaaatattta tacctagttg gaactactga tggtgtgttt ccgctgatta caaaggatag
     8821 tggaatattg agtgataatg atagggaaag tcttggaaac aaaggaatcg aagttgatat
     8881 tgatagtaag actaggagtt ttgaagaaca gtttcttgta tataaagctc ttacttcgac
     8941 atctaagaat ttaaccataa catatccaat atcagaccat gaaggtaaaa cgcttagacc
     9001 atcaataatt atatcaagac ttaagaagat atttccaaat atagaaaata aaagttattt
     9061 agtggaagaa aataaaagca ctgataaaga tatacttaaa aaaataacgg ttaaatcccc
     9121 tacatttaat gaacttataa acataataaa aaattatgac agtgatggtt acaatacaga
     9181 agagattaat agtatttggt tagatatata taggtactat ttaaaagatg aagtctatag
     9241 ttctataaca aaaaaagtta taaaaggtct tagttatact aatcaagttc ataagattga
     9301 agagaaaaaa ataaggtcat tgtataaaag taattctctt agcatatcta ggcttgaaaa
     9361 atatgctgaa tgtccatttg cttattttat acaatatggt ctaaaagcaa aaaagcgtaa
     9421 agagtattca tttacaccac cagatttagg aacttttatt cataatattt tagataggtt
     9481 ttcaaaagaa cttttacaag ataatttaac ttggagagat attgatgaaa aatatataga
     9541 attaaagata ggtataatag ttgatgaaat aattttaaag ataccaggat atatattaaa
     9601 tagttctgag aggtataaat accttgcata tagattaaag aatatgttga caactgctat
     9661 aactataatt agtcagcaaa taaaacaagg ttcatttgaa ccaatagatt atgaagttaa
     9721 atttggcgac aatggaaaat atccacctat aaaaatggtg ttagaaaatg gacaagaagt
     9781 aagtttaatt ggacaaatag atagagttga tgaatttgaa gaaggagaaa ataaatatat
     9841 aagaataata gattataagt caggcaataa gtccataagt ctaacagaaa tatattatgg
     9901 tctacaatta caattacttg tgtatttaga tgcaatcctt gaaagtacaa aggatgaaga
     9961 tataaatata aatccagctg caatactata ttgtagaata aataatccaa tagcaaaatt
    10021 taatgaagat aaagatgatg aagaaataca agaagcaata ttaaaagaac ttagaatgaa
    10081 ggggcttgta gtaaaagact ctcacatagt taaagagatg gataaatcat taatagatgg
    10141 agaaaggaaa aactctttag taataccagt aggtcttact aaggatggaa atgtaggtaa
    10201 aagtacttca gcaataagct atgaggattt caaactgctt agaaaatatg taaggcatgc
    10261 tataaaggat ttatgtgaag aaatgttaag tggagaaata cgtatagctc catataaaca
    10321 taaagatgga acatcatgtg acttttgtga ttactctgct atatgtcagt ttgattcaac
    10381 tataaaagat aacaagtata aaaatttaaa taataagagt aatgaagaga taataaaaat
    10441 gatgaaagga gatgttaatt agtgagttct cctaaatgga caaaagagca attagaagtt
    10501 atagaaagta gagaatgcaa tttattggtt gctgctgctg ctggttcagg aaaaacagcc
    10561 gtgctagttg agcgtataat tcaaatgata acaagtagag aaaatccaat tgatatagat
    10621 aagttattag ttgttacatt tactaatgct gctgcgtcag aaatgagaga gaggataggg
    10681 gatgctatag gaaaagcctt agatgaaaac ccagaaaata aacatttaca aaaccaactt
    10741 gttttattaa ataaatctag tattacaaca atacactcat tctgtttgga tgttataaaa
    10801 tcaaactttc atagaataaa cttagaccct aatttcagaa taggagacca aactgaatgt
    10861 gctattttga aacaagaagc aatagaggaa gtatttgaag atttatatga agaaagagat
    10921 gaggggtttt taaatttagt tgaaagttat gcagaaagag gaggagataa agaagtacaa
    10981 gatattatct tgggaatata ttcatttgca atggcttctc ctgaacctaa aaaatggttg
    11041 attgactcag cagaacgatt taatattgat gaaaattttg atttttcaca gtctatttgg
    11101 gctagagcta tattagatac tgtaaaaata gagattaatg gtctttgtct aaatatggaa
    11161 agggcattaa aagaagtgga atcaatagaa gaattagaaa cttttgcaga aaagttatcc
    11221 gttgaatata aaaaaattgc tgacatttca caagcatgta ataaatcttg ggatgaggca
    11281 tataaaaaga tggcaagtat gtcctttgaa aattatgtaa aaggagtaaa aagaatttca
    11341 aaagatgctc cttcgtatat aaaagaatca aaagaaaagg caaaaaccat aagagataag
    11401 actaagaagt ctttagaaag tatagtaagt gctacattca ataaagataa tgattctatt
    11461 agagaagaaa taaaatatct ttataacata gttaaaccaa tatctagtgt tgtactgaga
    11521 tttgaagagg aatatagcaa taagaaaaga gaaaaaggaa taatagattt taacgatata
    11581 gagcattttg cattaaatat acttacagat gtagatgaaa aaggtaatat tgtaccttct
    11641 gatatagcag ttggatatag aaacaagttt tatgaaatat ttatagatga atatcaggat
    11701 agtaatctag tgcaggaagt actgcttaaa gctgttgcaa atacagaaac tccaaataga
    11761 tttatggttg gtgatgtaaa acagagtata tatagattta gacaagcaaa gccagaatta
    11821 tttttgcaaa aatataataa ctataatgat aaaaagggaa gttcccatag aaaaataatg
    11881 ctttacaaaa attttagaag tagagaagaa gttgtagatg ctgtaaatta tatatttgaa
    11941 aatataatga atgagaatat aggagaaatt gaatatacag aaaaagaaag actaaattta
    12001 ggtgcagatt ttaatgtgga tacagacgag aaatctatta ttggtggagc aacggagata
    12061 cacctaatac aaaaagataa taaacttgat gatgatatta taaatgataa agacgataga
    12121 attaataaca aagaaaatga aatagaggaa gaagaaaaat tagataatat acaacttgag
    12181 gctagaatgg ttggaaacat tatcaaagat ttaatgaaag tcaatgaaga tggaaaaatt
    12241 caaaaggtct atgataaggg aatagatgga tatagacctg tggaatttag agatatagtt
    12301 attcttttaa gagctacatc tgcatgggct ccagtgtttg cagatgaatt gatgaatatg
    12361 gatataccaa catatgctga tgttggagtg gggtattttg atacgattga aataaaaaca
    12421 atattgtcat tacttcaaat aatagataat ccaatgcaag atatacctct tatatctgta
    12481 ttaaaatcac ctatatttgg atttacacca gaggatttga ttgatattag agttcagagt
    12541 aaagataaaa ttttttatga ggttttaaaa agtacagcag agtatgatgg atttacagat
    12601 tctcaaaatg aaaatgagtc tgagtttata ccaagtgaag agtgcataaa caaaagtaaa
    12661 gattttttaa ttaagctaaa ggaatttaaa gaaaagtcaa tgtacatgag tacagatgaa
    12721 tttatatggt acttgtacac aaggactgga tactatgcct atgttggagc attgccaggt
    12781 ggaagtcaaa gacaagctaa tttaaaagta ttgtttgaga gagcaaaaca atttgaagaa
    12841 accagtctta aaggaatatt caactttgta aattttatag agaaattaaa aaaatctagt
    12901 tctgatatgg gaagtgcaaa aacacttggt gagaatgcaa atgttgttag aataatgagt
    12961 attcataaaa gtaaaggtct agaatttcca gtagtcatat gctctgcaat gggtaaaaat
    13021 ttcaatactc aagattttaa aaagagtatt ttatatcatc ataatttagg gtatggacct
    13081 caatttgtag actatgagag aaggatttct tttccaagta tagccaaaga agcattaaaa
    13141 agcaaaataa atatagaaaa tttatcagaa gagatgagag ttttatatgt tgcatttaca
    13201 agagctaaag aaaaattgat tataactggt tctactagaa atatacaaga tagtataaag
    13261 agatggtcaa atggaattga aagtttagat acaatatcac aatacgagat attaaaaggt
    13321 aaaaattttt tagattggat aatgccttgt gtattaagac atagggattt atataatcta
    13381 ctagaagaag taggattaga cgcagttttt aatgttgaac ataattcaaa atggtatgga
    13441 aagttgtgga ataagaatga tattttagtg gaaaagaaga gtgatgaaga aaaagaaagt
    13501 attgaagaaa ttcttgaaaa aatagatgta gataatcctg acagtgatta ttacagtgaa
    13561 atagaagaaa aattaaacta tatatatcca tatgaattta gtacaagaaa acctgctact
    13621 atatctgtta cagaaataaa aaagatacaa aataattatg aagaagagtt aataaatact
    13681 atatttgaac aaaaagtaat attaaaaaag cctctattta ttcaaaatga agaagaaaga
    13741 gaaaaaataa gtggaacaga aagaggtaca atagtccatt tagttatgga ggttttagac
    13801 ttaaaaaatg taagtagtgt aaatgatata aaatcacaaa taagaggttt tgtttcaaaa
    13861 ggtataataa cagaaaaaca agctagtata gtaaatccat ataaaatata taaatttttt
    13921 gcctctaaca taggaaaaag aatgttgaat gctgaaatta taaatagaga aaaatcaatt
    13981 tatgcacaag taaatatgaa agacatatat atttatgaaa agcttataaa caatgacgat
    14041 aaaaaacttt atgataatga aagtgtcatg ttaagaggta tagttgatgc ttattttgaa
    14101 gaagataatc aaatagtttt ggtggattat aaaacagatt ttgtaaatga ggaaaatata
    14161 aatcaaataa tagagaaata taaaaaacag ttggatttat atgcagatat tattgaaact
    14221 ttaactggta agtcagtaaa agagaaatgt atatatttat ttggagttga tgaagctgtt
    14281 tgttattagt ttttatatat aaattaaacc taaaagatag aggaagggga aaaaatgaga
    14341 tttattcata catcagattg gcatctaggg aagtccctag aaggccattc tagaattgag
    14401 gaacaagcaa agttttgtga ggaatttata aaaatagtag aatcaaatga aatagatatg
    14461 gttataattg ctggagatgt atatgatact tctaatccac cagcacaagc agaaaaacta
    14521 ttttatcaga ctgtatcaag acttgccaat aatggtcaga ggtgtgtatt aataatttca
    14581 ggaaatcatg ataatccaga gagactctct gcaataacac ctctagcaca tgaacagggg
    14641 atacttatat atggttatcc attaagtgct acgatagaag ctaagtataa agggtttgaa
    14701 ataacatatg caactcaggg atgtacaaaa ctgaatataa atggagaaaa tattgtggtt
    14761 gctacattac cttatccaag tgaaaaaaga ttaaatgaag ttttttcaag tgaagatgag
    14821 tttgagaaac aaaaaaatta ttctgaaaag gtaggagata tatttagaag tttagaagaa
    14881 aattttagaa gtgatactat aaatatagcc gtatcacata tatttgtaat aggtggagag
    14941 agtactgaat cagaaagacc tatacaatta ggtggaagtt ttttagttga aagaaaagat
    15001 ttgccagaaa aggctcaata tactgcacta ggtcatttac ataaacaaca aaaagcttcc
    15061 gaacgtttaa atgcatacta ttctggttct ccacttcaat atagcaagga tgaaagagcg
    15121 tataccaaag gggcatacat agtggatata aaagctggtg aaaaaccaat aattgaagat
    15181 gtatatttta ataattacaa acctatagaa gtatttaaat gtaatggaat agaagaagca
    15241 ctagatatat gtgagcaaaa tcaagataga gagatttggt catattttga aataaatact
    15301 gatgagataa tatcacagaa tgaaattaaa aaaatgaagg aactattaaa agacataata
    15361 gaaataaaac caataataac atcttgttat gaacaagaaa gtgtagatat aaaagaaaag
    15421 tctatggcag agttgtttag agagttctat tcttttagta aaggtgtaga gccaaaagga
    15481 gaacttatgg atttatttct agatataata agtgaagaag gtgaatcagc agatgagacc
    15541 aattagatta gaacttacag ggcttaatag ctatattgat aaacaagtta tagactttga
    15601 aaaattaatt gaaagaggtt tgtttgggat atttggaact actggaagtg gaaaatctac
    15661 aatattagat gcaataacta ttgctatgta tggaaatata tccagaaata caaaagaata
    15721 tataaacagt gtgtgcgata aggcaattat atcatatgag tttgagatag gaagcaaaaa
    15781 cactagaaga agatacattg tagatagaac cattgctaga agcaaaacag gaacaaagac
    15841 ctctaatgct agattaatag aagtattgaa tgacaatacc caaaatgttt tagctgataa
    15901 agttgtggaa gtaaatgaaa aagtagcgca ggtcgtagga ttaacggcaa atgattttac
    15961 taggtcagta gttttaccac aagataaatt taatgagttt ctaagattat cacgtgcaga
    16021 tagaagagac atgttagaga gaatttttaa tcttgagaaa tatggaagaa gtcttggaga
    16081 aaaagtgaaa aagagaaaaa atatacagtt acaaaattta aaagatttga aatcaaaatt
    16141 aagtcaatat gatggaatta cagaggaagt atacaacaaa ataaaccaag aattaataga
    16201 gttaaaaaat ttggaaaaag ataagaataa tgctttagac ctagctcaaa aatcttatga
    16261 agaaagtaaa acagtatatg aagaacaatt aaagttagaa aaaaatgaac ttagaaaaaa
    16321 tgagcttgat ttaaaaaata gtgagataaa agaaaagatt gctcttgtag aaaatgatag
    16381 taacgctaaa aaggtagacc catacataag ttcagttcaa aatctagaaa aaaagataga
    16441 tgaagatagc tttgcagtaa gtaatttaga aaagaaatta gcaatattaa atcaggagct
    16501 tgaagttaca aaaaatagat atgaaaaaat aaacaaaatt aagaatgaag aagtccctaa
    16561 attgagtgaa gaaaaaataa gattgcaaca agcaatgaaa ttagaagaag agttagtttt
    16621 attagataga gagttaaaag agctaaaaga aagtggaatt aatttaaata agactaaagt
    16681 tgaattagaa aaagtaaagc aggtgtcaga gtccagaaaa gatgcagtta ctaaatctat
    16741 aaaagaagtt gaaggaaaga ttgataaagt aaatataagt gcagaattaa aacaaaaaat
    16801 atttctagca tatgaatacg agaaagatta caacaacgta ttggaagaaa aaaatcaaaa
    16861 gctaaataaa ctagaagaaa tactcaaaga gacagaaaat ataaatttaa aagttagata
    16921 tattgataaa ggtaagaatg atgtaaatcg taatttagaa aatttatcac ttcacttgga
    16981 tgttcttctt aaaaaatgtc ctggtaagag tgctgattta cttttaaaat ctgaatatgt
    17041 tactgaatta agaaataaag caaataatac taaagaaaat gaaattaaga aaagcagtat
    17101 acaagatgaa ttaaagataa tacttgaaag taagtttaat actgaaaggg aagtaaattt
    17161 actaaatgaa aaacttgaaa ataatagaaa gaacagagat gacctagaaa aagaattaga
    17221 agaactaaag tatttaaatt tagcctctga acttagacgt gaattaaaag aaaatatgcc
    17281 ttgtccagtt tgtgggtcaa aacatcatga aaatcatgat ataactaagt atgatgaaaa
    17341 tatatctttt gtcaaagaaa aactggagaa attagaaaaa gaaaaaataa gtataagaaa
    17401 caatatagag gaattaaatg ctaaagtaag tgggtattta tctatagaaa aaatgaagac
    17461 taaagaactt gaagatgtaa aaggaaaact aggggggatt ccatctagtc aattattaaa
    17521 aaaacttgat gaagaacaaa gaaaacttgc attgttaaaa tctaatattc aggagtggga
    17581 gaaagaaaaa gagagtactg aaaataaagt aacattagct aaagaagaaa aaaataaaat
    17641 tgaaaaagaa gaattaaaaa taagagagag tctgaataat tataagaaat taacaagaga
    17701 tttaaacata gaaatagaag gtttagaaaa taaatgtaaa aaaattaaac aggaatacct
    17761 aggattaaag acgattacta aagtctctaa tctattgtca aaagtaaaag aaataaggga
    17821 gaatgaaaaa gaattagaat tactaagtac tgggcattca aatttattaa aaaatagaga
    17881 ctcactagat attaaaataa gagaaaatga gagtaaacta catgaaatag agatagaatt
    17941 aataaaggct agagaattat atgtagaaaa gaaattgagt agagataata agtataaaga
    18001 agttattagc ataactaaag gtgatttagc taaaaatctt ttacataatg ttgaagaaaa
    18061 tatatgtaag atattagaac aagaagaatc aagtaagaaa aaattggaag agcaaagatt
    18121 agaatatgaa aaaaacattg ctgaaaagca caatatagat ggtagactta aaactgctaa
    18181 ggaacaatat aaagaccaaa aatcaacact aaataaacta ttggcagaaa ataaatttga
    18241 aagtatatat gcagtaaaaa gagctttatt agatactgat gcagtaaaaa aattgattga
    18301 agaaatacta gagcatgaag aagaacaaaa gttattatca tttaaaataa aatcatcaaa
    18361 agaaaaatta aatggaagaa gcataaagaa ggagtacttt gaacagttaa aagatgaaat
    18421 ttataatttg aaagtagaaa taggaaatat atccaaagat attggagcta atcaaaatca
    18481 gttaataaca ttaaaagact ctttagataa gataaatgat tttaataaac aacttaaggt
    18541 agttgaacac aatgtggact tattggaaga attagataaa tgtgtacaag gaaataaatt
    18601 tgtagaatat gtttctacaa accaattaaa atatatagcg ttggaagcat caaaacgatt
    18661 ggatggaata acaaaaggaa gatatgcact tgaaattgac tcaacactaa actttataat
    18721 gagagataac tttaatggag gagaaagaag aagcattgat actctatctg gtggagagac
    18781 attcttgaca tctctatcat tagcacttgc tctttcatct caaatacaat taaagggaag
    18841 tgcaccatta gaatttttct ttttagatga aggttttggt tcattagata gtgaactttt
    18901 agaaattgtt atagaatcat tggaaagatt gcatagtaat aatctaagtg tgggtataat
    18961 aagtcatgtc gaggaactta aaaatagagt tcctgttaag ctattagttt catctagtga
    19021 ggctggaata ggttcaaaag taaaaattga atatagttag aaaatatatg ttaattgaat
    19081 atattatcta atatttccaa ataatatgta attgtgatat aataaaaact aatattaaag
    19141 ttatttataa ttaatattaa tataaaaaca tgtaagtagg agtgtggtaa gtgttggaat
    19201 cgcccaataa tttgattcag attatttttt taatagtatt acttataggg tctgcatttt
    19261 tctcagcatc tgaaacggcc ttaatgtcgt tgagtaaaat cagaatcaga tatatgcaag
    19321 atgaaggagt taaaggagct aagttagtaa gttcattaat agaaaatcca aataagcttt
    19381 taagttctat attggttgga aataacgtcg taaatatagc agcaacatcc atatcaacat
    19441 ctttgtttat aggattaatg ggagaaaaag gagtggcact tgctacagct gttatgacag
    19501 tattagtatt aatatttggt gagattactc caaaaacaat agcagcaaat aattcagaaa
    19561 aggtttctct attagtatct aaacctataa aagcaattat atttatatta agaccaatag
    19621 tatggatatt taatataatt acaaatatta tatttaaatt atttggtata acaaataaag
    19681 gagctaaatc attcataact gaagaagagc taaaaactat ggtaaatgta agtcatgaag
    19741 aaggcgtcct tgaaatggaa gagagagaaa tcataaataa tgtttttgaa tttggagata
    19801 tgcaagctaa aaatgcaatg gtacaaagaa tagatatggt agctatagat atggaagata
    19861 gttatgatga gataatacag gtatttaaaa ctgaaaaatt aagtagaatg cctgtgtatg
    19921 aagaaactat agatgatatt gtaggaatac ttaatataaa agatattata tttttatctg
    19981 atgaagaaat agagtcattt gatattaaaa attatatgag agaacccttt ttcacgtatg
    20041 agttcaaaaa gataacacaa cttcttgaag agatgaaact tgaaaaaagt cagatggcta
    20101 tagttgtaga tgagtatggt ggaacatctg gacttttaac tatagaagat ttagtagaag
    20161 tcattgttgg agatatagag gatgaatatg atgaagaaga ggatgaaata caagttataa
    20221 aagaagatga gtatattgta gatggaagta ctaaaattgg tgatgttaat gaacttattg
    20281 gtgtaaactt ggaatctgag gagtttgatt ccataggagg ttttataatt ggacacctaa
    20341 gcagattgcc agaagaaaat gaagtaattg aagttgataa tataagattt tgtatagaaa
    20401 gtatagaaaa aaatagaatt aaaaaaataa gaatatatac ataatgtaat aatgttctta
    20461 aatttattag aagtgtataa atataaaaga tatcttttat atttatacac ttctttttat
    20521 tttgtattca aataaaacta gtatgaaatg gacaaaataa aaatataaat tagaagaaag
    20581 gagattttta agatgagcat actagaaaat aattttttat acaaattaaa aaacaacact
    20641 atcttttttt gtatatatac attgttattt atttttattt acaaagcgtt tccatacata
    20701 gctccatttt ttctaggtgc tataatagca cttatgatta atcctatatc acaaaagtta
    20761 gaaaataagt ttcgtataaa taaaggtatc tctactcttg ttctaagttt tcttgcagtg
    20821 gctatagtca gtacagttac tacaataata gttataaatt caatgaaaga attaatggga
    20881 tttttaaata atatatctgc taatcctgag gatataagta atactattat gtatttttta
    20941 aataaaataa atgactttat gaaatcattt caagaaatag ctaactttga tgtagaacaa
    21001 ttagtaaaca aattcagtgg tgaagtaatg caaattacaa aaaatcttct tactagtata
    21061 cttggattgg ctacttctat tccatatatt ataatattta taattacctt gtttattgct
    21121 acatacttta tagcaaaaga ccttgataag attgaaaata gtttttataa tatgtttact
    21181 gttgatgtta gaaagaaggt aaaaaacgta aagaaagagg cagggctttc acttgttgga
    21241 tatataaggg cctatacaat acttatggct ataacatttt ttgcaatctg gggaagtttt
    21301 gctttatttg gattgaaata cggtctaata gtagggtttg taggagcttt aatggattta
    21361 attccattcc taggtataat aacaatatat cttccagtaa ttgtttatta ttttcttata
    21421 aaaaattatt ttatagctat aagtatgact gtgatatttt ttgttttgtc tttgattaga
    21481 gaaatacttg aacctaaact agtatcagta aatgttggac taaatccatt agctacccta
    21541 gcagcgattt ttattggaat ccaagtaaaa ggaataattg gagtaatttt ttgtttgggt
    21601 ttggtatgta tgcatgatat acttaagaag gtggatattt tttaattata ataattgata
    21661 gattttttaa aaataaaatt ttattcacag gtaaataaaa aaatattaat cttattaaga
    21721 aagagggtat atacgtgaaa caaaaagtag tggaaagatt tttaaaatat gtatcatttg
    21781 atacaacatc taattctcag tgtgagaact gtccatcttc agaaggtcaa agagttttag
    21841 ctaagtatat agttgaagag ctaaaaacaa tgggtgttga tgatgtgagt ttagatgaaa
    21901 atagttatat aatggctact ttaaaaggaa atactgatgg tgtggatact ataggattca
    21961 tatcacattt agatacaatt gaagatgtta gtggaaaaga tattaaacca agaataatag
    22021 aaaattatga cggaaaagac atagttttaa atgaagcgtt aaatgttatt acgtatgtaa
    22081 aggattctcc agagttggaa gaatttaaag gtgacgattt aatagtcact gatggaacaa
    22141 ctctacttgg ctctgatgat aaagctggta tagctgagat agtgactgca atagagtatc
    22201 taataaatca tccagaaatt aagcatggag atataaaaat aggatttaca ccagatgaag
    22261 aaattggtag aggtgctgat ttatttgatg ttgaaaaatt tggagcaaaa tatgcatata
    22321 ctttagatgg aggaatagtt ggagaacttg aatgtgaaaa ttttaatgct gcaaatgcaa
    22381 ctattactat acatggtaga aatgttcatc caggttcagc taaaaataaa atggtaaatg
    22441 ctatacatat agctgctgaa atatcagaaa tgttcccagc agatgaaaga ccagaaacaa
    22501 cagaaggata tgaaggtttt tggcatttaa attctatagg tggaaatgtc gagaatgtaa
    22561 gtatggctta tattattaga gaccattgta gagaaaaatt tgaaaataga aaatctatta
    22621 tgataaagaa tatagaaaaa ataaataaga aatacgataa tagagtggaa ttggatttaa
    22681 aagactctta ttacaatatg aaagaaaaga ttgagccagt tatgtttata gttgatatag
    22741 ctaaagaagc tatggaggaa ttaggtataa aaccacgttt agttcctgta agaggtggta
    22801 ctgatggagc aagattatct tttaatggat taccttgtcc aaatatattt actggtggat
    22861 taaacttcca tgggaaaaat gagtgtatac cagttagttc tatggagaaa gctactaaac
    22921 taattgtaag aatagctgaa aaatatgctg aaagagttta gttaaaaggt atttaaaaat
    22981 taagcattta aagttataat agctatatca ttctttataa gtcaagctga ttataagctt
    23041 gtgttgtatt taaaatggta tagctatttt tgtaattatt tttataaaag ataattattt
    23101 ttagtttagg gtatcaataa aaagtatgaa tatcaatagg tattaacatt taaaaggggg
    23161 aattgtattg aaaattaaat ctaaaaaaat aatagcattt gcactttcac ttgggattat
    23221 ggtgccaagt tgtgtatatg cagatactat tagtaaaaat caaaatgcac aggtagatat
    23281 gaacaattat cttcaaggta gaaaatctcc aaaggaggaa aaacttattg gtgaagatag
    23341 atttgataca gcgataaaaa tatctcaaag tggttggaat aatggttcag aaagggtgtt
    23401 tctagttaac tcaaattcat tgccagatgc attggcttca actcctttgg caagtaaatt
    23461 ggatgcacca atactgctta caaataaaaa tagtatacca tataatgtaa tagaggaaat
    23521 aaaaaggctt aatccagcag aagttatttt aattggaagt gaaggagcta tttcatcaag
    23581 tgtaaaagaa tctcttgaag atatggaagt attagtcagt agaatcggtg gagcagatag
    23641 agaagaaaca tctttacttc ttactagaca gctagatgat actggtgatt taggtgtttc
    23701 aaaagtggca gtggttaatg ggtataatgg actggcagat gcaacttcaa tatcaagccc
    23761 agctgcaagt gataatacag ctataatata tacaggtaag gatagcataa gaagtgaggc
    23821 aaagaatttt attacacaaa actcaactaa gacatacata gtaggtgggg agtacagtat
    23881 aagtaaaaaa cttgaaggac agttagtaaa ctcagaaaga ctagcaggga cagatagaaa
    23941 agatactaat gcgaaagttt tagaaaagtt ttatggaaaa tcaagtaagg ttaataatat
    24001 gtattttgca aaagatggaa gtggtagaga agctgattta gttgatgggc ttgctgctgg
    24061 agtattagca tcaaaaacaa agtcacctgt agtacttgca agtggaagtt taagtagtgc
    24121 acagaaaagt tttataaaaa aagtaaaggc tgataaattt gtacaagttg gtggaggtaa
    24181 aaatagtaaa ccatatgcag aagcattagc cttacagtaa tattgtgtaa atcaaaatta
    24241 atatataata atagcaagta aaccaagttg cacttcaata tatataataa aataagtaaa
    24301 ctaagctatg tttcaatata atatataata aaataagtaa actaagttat atttcagtat
    24361 aatatataat gaaataagta aactaagtta tactccaata taatatataa tagaagcaag
    24421 taaactaagt tatatttcaa tatagcatat aataaaacaa gtaaaccaga ttctatttaa
    24481 ttagaagttt aaggtattgt acttaaactt ctaattgaga tagaaataaa atggtttact
    24541 tgtttttatt atgagtttaa taaattaaag cttattttat ttttattaaa aatttactaa
    24601 tcattgatat ttattatatt tccagtattg atgtcaatta agtttatatc aagttcaagc
    24661 tcatcctcat catcagtttt tatgatatct ataattgcga cagaatggct tccatctttt
    24721 gggatagaag tacttcctgg atttattact attaaattat catccatgta tagttttttt
    24781 acatgagtat gtcctaaaac taatatgtca ccacccattt tctttgcttt gtcaataatt
    24841 tcttcttctg attctatata accgtgattc aatataattc taatttcact aaattggctc
    24901 atgacataag gactctgaat aggatgttct ataaccatct ggtcaacatc tgcatcacag
    24961 ttccctttta caatcacaat gttttctaat ttatttaatg tatcaataaa ttttttagga
    25021 ttatatcctt ctggaatatc atttctaggt ccatgatata agacatctcc accatgtaat
    25081 aaaacatcac aatcagataa tacatttaac gctttttcaa agtaaagtaa gctaccatga
    25141 gtatcactca ttattcctat tttcatatta aaaatcctcc taagtacagt ctataaaaat
    25201 ttttcagata ctctatgcca aaactcatag tttgacattc taagtaattt tatttttgca
    25261 tcagatatac taacttttat attttcgatt tgtctaaatc tgtgctcaac tccatcaacg
    25321 acaatcaata cagaatcttc aaatctatat tctggtgcaa tctttataac agattcattt
    25381 gaacatatta tacttgatgt aaagcaccta tatgcattgg tatttatcgg atgtaaaggt
    25441 gtaatctgca taagttcaag atttatatca acaatactac ctccagcaga atagttatag
    25501 gctgttgaac ctgtggaagt agaaataatc ataccatctc cactaaaatt ttgtatatgt
    25561 ttattatcaa ggcttaaatt taggtgtata gtcctagact tgtctcctct tataacaacc
    25621 tcatttacag caagcatatt agaaccacta gtagtagtat atacttccgc attaagaagt
    25681 gacatttctt gaataatata atcttttttt gtataagctt caataaagct atcaatctta
    25741 tctggtaaaa tatcaggaaa aaacccaaga tgacctgtat ttattcccat tatgggaatc
    25801 tcaggaaaat cgaaatctct aactgttctt aaaaaagagc catcaccacc aattgatata
    25861 ataagctctg tgtctggata aatatctgaa tacacttcaa agccagcatt gataagtttt
    25921 ctagttaaga gttctttagt ctcaagggac ttatttaatt ggtttgtatt tatagttata
    25981 attcttttca tatattcacc tcttcatact ttgtattata acatagtttt ataattctta
    26041 atttataaat ttataaatga cctttgtaat gaatgtgtta aaatatgtat aggtgggtat
    26101 aaaaaaatgc ataagaggtg aagatgtgtt tagcataagg aatatcacaa aaaaattagg
    26161 aaaattcaag ttaaataata taaacttaga gttaaaggaa ggggatattg ttgggattat
    26221 aggaccaaat ggttcgggaa aaacgacttt aataaaaatt ataatgggga ttattgatgc
    26281 agatgaaggt gaaattgaac tttgtaatga aactattgaa aattctccaa taagctttaa
    26341 aaacaatatt ggttttgtat atgattcttt acaattttat ccgcatttaa aggttaagga
    26401 atttagaaaa atagtttctt tattttataa gaattttgat agagaaaggt ttgatgaata
    26461 ccttaataag tttgatatag aagaaaatat gcatattgaa aatttatcta aaggtcaatc
    26521 tgagaagctt atgttatcaa gcgcacttag tcataatgct aagttattga ttttggatga
    26581 accaactgct ggcatagacc caattgtaag aactgaaata atgcagtact tacaagattt
    26641 tgtgaaaaat ggaagtagta gtgtaataat ttctactcat aatactgata atttaattaa
    26701 aattgttgat tatcttgttt ttataaatag aggaaatcag atttttactg ttaagaaaga
    26761 attaatagaa caagaatata agataattag ggcaaataaa gcagagttag aagcaattaa
    26821 agaaagcata gttggtgtga aagagtataa atattataat gaggcacttg ttaaagttgg
    26881 agatagcttg aaagtaaaaa gcctattgat agaaattgat aagcataagg tcaaaaatcc
    26941 tactatagaa gaactaatgt attattatgt aaatgaggtg agatgatgtt caatttaata
    27001 agaaaagatt taataatagg gattagttca gatggtatcc gtaatttaaa gtacatattg
    27061 ctattttttg tgttttattt tttccttaat tcaatttcat attatacagt aagtattgtt
    27121 gttagttatt tgatatttat aaatacattt gagtgtgatt atgaaaatga ttcaaggatt
    27181 tttataagga gtatgccagt tagtatagaa gatatagttt actcaaaata tttattaggt
    27241 gtaggattaa taatttctgt aacaataatt gtgtccttac taagtaaatt gacatcacta
    27301 gtgttcttta gaaatatggt tttaaatgat gtattttttt ctgtaaatat atttttagca
    27361 attttgacga ttttactgcc tttaattttt aagtttggat atggaaaaat gaaagtttgt
    27421 ggttttatag taagtatttt aatttacttt gtatatggaa gtcttttgaa gatgattagt
    27481 atgattgtat atcaagtaaa gcattttaat tatagtaaag ttggaggagt atatctttca
    27541 aattatgtaa ctgatatagc taatactaag tatataaatt tatatagtat gacattttta
    27601 acaataataa tttttataat atcaatgtat ttttctatta agatttcaaa aaagaataag
    27661 tttaattatt aaaattttaa ttaatattat agcacaatag cacaaaatat aaggagacta
    27721 aaaatgaaga agtttataaa agtttcattt tttattttgg ggatttttac actattcata
    27781 gctataaata aattagtata tagagatatg gtaagtgtca aagattatga aataaatcat
    27841 ttagaggaaa ttgtttttga ttttgatagc aggagaagta gagatgttgg tactattgta
    27901 agatttaaaa taagcaataa tagtaaatat agttataaat taaacagtgc taaaatgaag
    27961 tttgaaaatt gtgtggaaaa taaaaaggga atgaataagt gttctgcata tgtaaatgta
    28021 gatttattta atgaaaaaaa ttctataact gaaagaactc tgaaatatgg aataaaacca
    28081 aataatcaag gttatgttga ttttgtaatt ccaaaaggac taaattttga ttataggtac
    28141 tttaatgaat ctggtatgag tgtagagtat aaaggagaat atattgtcaa tattccaatg
    28201 gcaaaaggac tttatctagt agttggaaaa aataatgata catggaatgc taatatcatg
    28261 gaataatttg aaaaataaat caattataga tataattaag aataatatga aatttataaa
    28321 agttcagact aggagggata tttaatgtca ataagtaatg taagagagta ttttaaacaa
    28381 tttggcaagg aagacagtat attagaattt gaacaatcta gtgctactgt ggaacttgca
    28441 gctgaagcag ctggggttat tccagcaaga atagctaaga cactctcatt taaaatagga
    28501 gatgatgcaa ttttaattgt gacagctggt gatgctaaga ttgataataa gaagtataag
    28561 gctgaattta attgtaaggc taaaatgttg acaccagaag aagtcttgga gtttactgga
    28621 catgctattg gtggagtctg tccatttggt ttaaaaaatt ctataaaagt ctatttagat
    28681 gattcaatga aaagatttga tacagtattt cctgcatgtg gcagtagtaa ctctgcaata
    28741 gaacttacat gtgaagaaat ggagaagttt tctaagtgtg aaaaatgggt agatgtttgt
    28801 aagaattggt aaaaaaatat agtaaactat agtaggaatt agtaaaaaac tacctctgta
    28861 tacaatctat acagaggtag tttttttgtg taaatattta taaatctaag aggaaaatct
    28921 aatttaaact aataatccaa aataaagtta aaaaattctg attttttttc gaaacaataa
    28981 aaaaatgaca aaaaagtgga aaaaatgtaa taaatattgt taaaaaaata attagaaatt
    29041 attgaaaaat tatcctttga gtgatactat tatagatgta agatatttaa aaataaaaaa
    29101 tagtcagata aaaatacgat tatttagctc tattaaaata atttttatac gataaaaatc
    29161 ttctgtacat ggctaaaaga cagatataca gacaatattt aatgtttaat ataccctaat
    29221 ataaatatcg taaacaaatt attttatctg taaccagtgt gaaagaaatc ttattctaac
    29281 ttgaaatttc acaaaattcc aaaaagcgag atttttttta agtatagttg attttaaatt
    29341 aacaatttat gattaaatta atgtcataat tggttagtat aatcacatat aaatatagag
    29401 cgtagtttga ttaaggttat aaatttctcg acgtatattc aaatacctta ttatagatgt
    29461 tgccgagatt ttaattaata aatgaaaata aaatatttat aaaatactga ggaggctatt
    29521 atggatttaa attctaaaaa atatcagatg cttaaagagc tatatgtaag cttcgctgaa
    29581 aatgaagtta aacctttagc aacagaactt gatgaagaag aaagatttcc ttatgaaaca
    29641 gtggaaaaga tggcaaaagc aggaatgatg ggtataccat atccaaaaga atatggtgga
    29701 gaaggtggag acactgtagg atatataatg gcagttgaag aattgtctag agtttgtggt
    29761 actacaggag ttatattatc agctcataca tctcttggct catggcctat atatcaatat
    29821 ggtaatgaag aacaaaaaca aaaattctta agaccattag caagtggaga aaaattagga
    29881 gcatttggtc ttactgagcc taatgctggt acagatgcgt ctggccaaca aacaactgct
    29941 gttttagacg gggatgaata catacttaat ggctcaaaaa tatttataac aaatgcaata
    30001 gctggtgaca tatatgtagt aatggcaatg actgataaat ctaaggggaa caaaggaata
    30061 tcagcattta tagttgaaaa aggaactcct gggtttagct ttggagttaa agaaaagaaa
    30121 atgggtataa gaggttcagc tacgagtgaa ttaatatttg aggattgcag aatacctaaa
    30181 gaaaatttac ttggaaaaga aggtcaagga tttaagatag caatgtctac tcttgatggt
    30241 ggtagaattg gtatagctgc acaagcttta ggtttagcac aaggtgctct tgatgaaact
    30301 gttaaatatg taaaagaaag agtacaattt ggtagaccat tatcaaaatt ccaaaataca
    30361 caattccaat tagctgatat ggaagttaag gtacaagcgg ctagacacct tgtatatcaa
    30421 gcagctataa ataaagactt aggaaaacct tatggagtag aagcagcaat ggcaaaatta
    30481 tttgcagctg aaacagctat ggaagttact acaaaagctg tacaacttca tggaggatat
    30541 ggatacactc gtgactatcc agtagaaaga atgatgagag atgctaagat aactgaaata
    30601 tatgaaggaa ctagtgaagt tcaaagaatg gttatttcag gaaaattatt aaaatagata
    30661 aatattaaaa tatacacaat aggtcgatat taaaatagat atggaggaag gatttatgaa
    30721 tatagtcgtt tgtataaaac aagttccaga tacaacagaa gttaaactag atcctaatac
    30781 aggtacttta attagagatg gagtaccaag tataataaac cctgatgata aagcaggttt
    30841 agaagaagct ataaaattaa aagaagaaat gggtgctcat gtaactgtta taacaatggg
    30901 acctcctcaa gcagatatgg ctttaaaaga agctttagca atgggtgcag atagaggtat
    30961 attattaaca gatagagcat ttgcaggtgc tgatacttgg gcaacttcat cagcattagc
    31021 aggagcatta aaaaatatag attttgatat tataatagct ggaagacagg cgatagatgg
    31081 agatactgca caagttggac ctcaaatagc tgaacattta aatcttccat caataacata
    31141 tgctgaagaa ataaaaactg aaggtgaata tgtattagta aaaagacaat ttgaagattg
    31201 ttgccatgac ttaaaagtta aaatgccatg ccttataaca actcttaaag atatgaacac
    31261 accaagatac atgaaagttg gaagaatata tgatgctttc gaaaatgatg tagtagaaac
    31321 atggactgta aaagatatag aagttgaccc ttctaattta ggtcttaaag gttctccaac
    31381 tagtgtattt aaatcattta caaaatcagt taaaccagct ggtacaatat acaatgaaga
    31441 tgcgaaaaca tcagctggaa ttatcataga taaattaaaa gagaagtata tcatataatt
    31501 taagggggga taaagaatgg gtaacgtttt agtagtaata gaacaaagag aaaatgtaat
    31561 tcaaactgtt tctttagaat tactaggaaa ggctacagaa atagcaaaag attatgatac
    31621 aaaagtttct gcattacttt taggtagtaa ggtagaaggt ttaatagata cattagcaca
    31681 ctatggtgca gatgaggtaa tagtagtaga tgatgaagct ttagcagtgt atacaactga
    31741 accatataca aaagcagctt atgaagcaat aaaagcagct gaccctatag ttgtattatt
    31801 tggtgcaact tcaataggta gagatttagc tcctagagtt tctgctagaa tacatacagg
    31861 tcttactgct gactgtacag gtcttgcagt agctgaagat acaaaattat tattaatgac
    31921 aagacctgca tttggtggaa atataatggc aacaatagtt tgtaaagatt tcagacctca
    31981 aatgtctaca gttagaccag gggttatgaa gaaaaatgaa cctgatgaaa ctaaagaagc
    32041 tgtaattaac cgtttcaagg tagaatttaa tgatgctgat aaattagttc aagttgtaca
    32101 agtaataaaa gaagctaaaa aacaagttaa aatagaagat gctaagatat tagtttctgc
    32161 tggacgtgga atgggtggaa aagaaaactt agacatactt tatgaattag ctgaaattat
    32221 aggtggagaa gtttctggtt ctcgtgccac tatagatgca ggttggttag ataaagcaag
    32281 acaagttggt caaactggta aaactgtaag accagacctt tatatagcat gtggtatatc
    32341 tggagcaata caacatatag ctggtatgga agatgctgag tttatagttg ctataaataa
    32401 aaatccagaa gctccaatat ttaaatatgc tgatgttggt atagttggag atgttcataa
    32461 agtgcttcca gaacttatca gtcagttaag tgttgcaaaa gaaaaaggtg aagttttagc
    32521 taactaattt cttggggagg gtattatgag tacaagtgat gttaaagttt atgagaatgt
    32581 agctgttgaa gtagatggaa atatatgtac agtgaaaatg aatagaccta aagcccttaa
    32641 tgcaataaat tcaaagactt tagaagaact ttatgaagta tttgtagata ttaataatga
    32701 tgaaactatt gatgttgtaa tattgacagg ggaaggaaag gcatttgtag ctggagcaga
    32761 tattgcatac atgaaagatt tagatgctgt agctgctaaa gattttagta tcttaggagc
    32821 aaaagctttt ggagaaatag aaaatagtaa aaaagtagtg atagctgctg taaacggatt
    32881 tgctttaggt ggaggatgtg aacttgcaat ggcatgtgat ataagaattg catctgctaa
    32941 agctaaattt ggtcagccag aagtaactct tggaataact ccaggatatg gaggaactca
    33001 aaggcttaca agattggttg gaatggcaaa agcaaaagaa ttaatcttta caggtcaagt
    33061 tataaaagct gatgaagctg aaaaaatagg gctagtaaat agagtcgttg agccagacat
    33121 tttaatagaa gaagttgaga aattagctaa gataatagct aaaaatgctc agcttgcagt
    33181 tagatactct aaagaagcaa tacaacttgg tgctcaaact gatataaata ctggaataga
    33241 tatagaatct aatttatttg gtctttgttt ttcaactaaa gaccaaaaag aaggaatgtc
    33301 agctttcgtt gaaaagagag aagctaactt tataaaaggg taaaaatcta attaaaaata
    33361 tatttgctgt taactagatt aaatagtatt ttaatctagt taatagaata taaatactaa
    33421 aataacagga ggttataact atgaaattag ctgtaatagg tagtggaact atgggaagtg
    33481 gtattgtaca aacttttgca agttgtggac atgatgtatg tttaaagagt agaactcaag
    33541 gtgctataga taaatgttta gctttattag ataaaaattt aactaagtta gttactaagg
    33601 gaaaaatgga tgaagctaca aaagcagaaa tattaagtca tgttagttca actactaact
    33661 atgaagattt aaaagatatg gatttaataa tagaagcatc tgtagaagac atgaatataa
    33721 agaaagatgt tttcaagtta ctagatgaat tatgtaaaga agatactatc ttggcaacaa
    33781 atacttcatc attatctata acagaaatag cttcttctac taagagacca gataaagtta
    33841 taggaatgca tttctttaat ccagttccta tgatgaaatt agttgaagtt ataagtggtc
    33901 agttaacatc aaaagttact tttgatacag tatttgaatt atctaagagt atcaataaag
    33961 taccagtaga tgtatctgaa tctcctggat ttgtagtaaa tagaatactt atacctatga
    34021 taaatgaagc tgttggtata tatgcagatg gtgttgcaag taaagaagaa atagatgaag
    34081 ctatgaaatt aggagcaaac catccaatgg gaccactagc attaggtgat ttaattggat
    34141 tagatgttgt tttagctata atgaacgttt tatatactga gtttggagat actaaatata
    34201 gacctcatcc acttttagct aaaatggtta gagctaatca attaggaaga aaaactaaga
    34261 taggattcta tgattataat aaataagaat ttgggaatta aaagtttaaa taaaattgtt
    34321 taaaaaacaa tttcggatat atgaaaaatc taatttaatg ggggtaatga atatgagaga
    34381 agtagtaatt gccagtgcag ctagaacagc agtaggaagt tttggaggag catttaaatc
    34441 agtttcagcg gtagagttag gggtaacagc agctaaagaa gctataaaaa gagctaacat
    34501 aactccagat atgatagatg aatctctttt agggggagta cttacagcag gtcttggaca
    34561 aaatatagca agacaaatag cattaggagc aggaatacca gtagaaaaac cagctatgac
    34621 tataaatata gtttgtggtt ctggattaag atctgtttca atggcatctc aacttatagc
    34681 attaggtgat gctgatataa tgttagttgg tggagctgaa aacatgagta tgtctcctta
    34741 tttagtacca agtgcgagat atggtgcaag aatgggtgat gctgcttttg ttgattcaat
    34801 gataaaagat ggattatcag acatatttaa taactatcac atgggtatta ctgctgaaaa
    34861 catagcagag caatggaata taactagaga agaacaagat gaattagctc ttgcaagtca
    34921 aaataaagct gaaaaagctc aagctgaagg aaaatttgat gaagaaatag ttcctgttgt
    34981 tataaaagga agaaaaggtg acactgtagt agataaagat gaatatatta agcctggcac
    35041 tacaatggag aaacttgcta agttaagacc tgcatttaaa aaagatggaa cagttactgc
    35101 tggtaatgca tcaggaataa atgatggtgc tgctatgcta gtagtaatgg ctaaagaaaa
    35161 agctgaagaa ctaggaatag aacctcttgc aactatagtt tcttatggaa cagctggtgt
    35221 tgaccctaaa ataatgggat acggaccagt tccagcaact aaaaaagctt tagaagctgc
    35281 taatatgact attgaagata tagatttagt tgaagctaat gaggcatttg ctgcccaatc
    35341 tgtagctgta ataagagact taaatataga tatgaacaaa gttaatgtta atggtggagc
    35401 aatagctata ggacatccaa taggatgctc aggagcaaga atacttacta cacttttata
    35461 tgaaatgaag agaagagatg ctaaaactgg tcttgctaca ctttgtatag gtggaggaat
    35521 gggaactact ttaatagtta agagatagtt ttagattata atatttacaa attaaatatt
    35581 taattatgaa tttaacctgt aagaataact atttgttatt cttacaggtt tttatagtta
    35641 aaaataatta ttatctatta aacaaaaata gtgtaaaata tataatatca tgattttgaa
    35701 gatataaaaa gtaggaagat ataaaagaaa gtaggtaaaa gtttgtttaa aaaagagaat
    35761 caaagatata atcttatatc gtatacaaat gaagaagaaa tgactttaaa agaagtttta
    35821 ttggacaagc taaatttctc agttaggtca ttatcaaaaa tgaagaggga aaagagtgtt
    35881 ttagtaaatg gagtatataa aaaaccaagt ttaaaggtgt atagtggtga tttaatagaa
    35941 gtaaaaatag acgaggaaaa agcaaatttt gaacctcaag atttaaattt acagataatt
    36001 tatgatgatt ttgatataat tatggtgaat aaacctccgt ttatggtagt tcacccaaca
    36061 aaaagccact atgataaaac aatagcaaat ggtattagtt actatataga taatcaaaaa
    36121 gaaaatgtaa aaataagatt tgtaaatagg ttagatatga atacttcagg gttagttata
    36181 gtagcaaaaa atgcttatgc acatcatact ttgtctacag caatgagtga aaataaagtt
    36241 gaaaaaaagt atataacagt agttgatgga attataaaag aaaatgaggg aactatagat
    36301 gagccaattt atagacctac agaagattca ataaagagga taatagatga aagaggacag
    36361 tcatctgtta ctcactataa agtaatagaa agactagaaa atgcaactgt attagaagta
    36421 agcttagaaa ctggtagaac acatcaaata agagtacata tggctcatat aggtcatgga
    36481 ataataggtg atgagttgta tggttatgta gatgaagagc taataaatag gcaagcactt
    36541 catgcatata agttagagtt tgaacaacca agaacaaaag aaaaattgaa atttaaagca
    36601 gatataccag aggatatgaa agagttaata tcgaaattaa gataatgggg tgatatatat
    36661 gataatacat aaatttataa tacatgtttt ggacaaaaat agtgatgttc caatattaaa
    36721 tgactttgaa ggcaaagtta atcaagaagt agatggtttt ttccagaaag ctataaaaag
    36781 aattgcaaaa gatgaggatt taagaaaagg tgtttttaaa gattataatg acaatttaat
    36841 taaaaactgt tgtgaacaaa taatatatga tgaaagtact tttttgaaaa attctaaaga
    36901 aattgcatct tacttgtttg atgttatgaa aattaatgct gcactagaat cttgtgattt
    36961 ggcaatttgc ttatacacta ttaaagatga aaagagtgta gcaatactga aattagatta
    37021 taaaaagttg tacactcatt caattgaatt tgtggatgat aaatttaata ttcaaatggt
    37081 ttcaaatgaa attggtatcc cagagacttt aagacaaaag caaggagctt tgattagtct
    37141 aagtggtata aatgatgagt ttcatctaag gcttttagat aaggatgctg aaaaagaagg
    37201 gtcagaatct aagtttgtaa cagaattttt aaatgctaaa aaaatagatg atgataagta
    37261 caagaccaag gtatttaaaa atacagctga aaattggata accaatgctc ttagtaatga
    37321 tataaagcaa gctgaagatg taagaagtat attaaattat acactgaagg aaaaacatga
    37381 agttgatata aatgactttg ttgataattc aattaaagat gatgagttaa aggatagctt
    37441 taaagaacat atggaagaaa aaggtcttga tgaaagtttt agtatagata aaaaatgggt
    37501 tgagaaaaag cttaaaaaaa gaagtataaa aacggataat ggttttgaca taaaagggaa
    37561 tctaactgat tttgaagacc caatgaagta tactgtaaaa caaaatcaag atggaactat
    37621 agatataata ataaagaatg ttacgtttta tgaagaaaag taatttatat acttagtata
    37681 taaattaaat ataagagcgt gtattttata tattgtaaat aaatgtaatc tagtctgtgc
    37741 gaactctaat ataatttatt atgtagaagt ttacacagac tatttatatt tgtagacaaa
    37801 acgatactat ttgttttctt cgatatattt acatatatca ccaatacatt taaagttctc
    37861 agcttcctcg tctggtattt ctattccaaa ttcatcttca agggccatta taatttcaac
    37921 agcatctaat gaatcagctt ctaagtcgtc cattaaagat gcttccatag ttatctcatc
    37981 taaattgtct acccctaatt gttctgctat tatttctttt attttctcaa acattttaag
    38041 cctcctaaag cagttttaat taattttaat gttagtttaa tataatatca agaatttttc
    38101 aatatggaat ctataaaaaa taataaaatt ttataaatgt agtaataaag tattatttga
    38161 tgaataaact ttattgataa caaatataac ttaggaggaa atgctatgaa atatgtagga
    38221 ctattactaa cttcagtagg aatgttttta cttatagcag taaattttta ttataattca
    38281 ataactttag atatgcaacg tatagaggat tatgtaatgg agaccaattt aatccttgaa
    38341 gatgtagctg aaaaggagag ttatgtatct aatgaaaaag aagactacat atcaaggtta
    38401 atgcatgtaa agaaaggaat agaaaattca aaaacatcct tcttgataga aagatataag
    38461 gagtacaaaa taaaatcaat agaaagttta atctatacta tatcagagga gaaaaaagat
    38521 tatctggatg aagttgatag atacaataaa cttggtgaaa aagaaataaa taaactaatc
    38581 aataaaaact ttttagaagt aacttatctg tctattacta catatattta attaaagaga
    38641 caaaacttag tctcttaatg attcaaggag gattagttat gacaaaatta gaagacaata
    38701 tggaacgttt ctttggagga tgcgaaggat tttttgggaa taaaatgttg ataataatag
    38761 ttatagtatt cttactatta tgcacagaca ttttagaaga cttattatgc gatgacaata
    38821 tatggatatg ggttatatta atagtattgt tattatttaa cttcgatgat ggttgttgtt
    38881 gctaaaaaat attgattatt aaataggtaa aaccagtaac ttatacaagt tatggtttta
    38941 ccttttttag ttcaaattaa aaaatttaaa aaaatagtaa aaatacatta gcaaaatgga
    39001 aaacaaatgc atagtatatg ttaggagcga aaagctcaac aaaatatcaa caggaggtaa
    39061 cgtataatgt tagatagatt ctttggagaa gaaggatgtt ttggtggagg aggatggtgg
    39121 ataatagtac tattcttcct attcttagct tttggagata gctgggcaga atttgacata
    39181 atggcatgga taccattcct aatagtttta ttaatacttt gctgctgtgg tggatgctta
    39241 gaataagaac acagttatta aaaaaaggag ggctttgtta tgttagatag attttttgga
    39301 gaagaaggat gctttggtgg aggaggatgg tggataatag tactattctt cctattctta
    39361 gcttttgaag attgctggag agacattgac ataatgtcat ggataccttt cttaatatta
    39421 ttgctaataa cttgttcatg tggtggattc tttgatggtg aagtaggttg cggctgctaa
    39481 tacttaaatc attagaataa aaaaatgctg gtattttata ccagcatttt tttattttat
    39541 tttttaatat gatttaaatt aagaatgaat attattaaat ttgttgaata tagggtataa
    39601 tataaaatat aatgtattta aatgtacttg cttttatggt aaaataaaaa cttatataaa
    39661 tgtagttaaa ataggaacct tcaaaaattt ggttcagttt tagataaatt tagtaaaata
    39721 aggaggatga agatgaaagg caatataacg ataaaagatg ttgctaaaca agcaggagtg
    39781 tcaatatcta ctgtatctag agttataaat gattcaaaac ctgtaactga tgaagtcaaa
    39841 caaaaagttt tagaggttat aaaagagact ggatatatac caaatccact tgctagaagc
    39901 ttagtaacaa agaagagtca attaataggg gtaatagttc cagaagtttc agattctttt
    39961 gttaatgagg tgttaaatgg gatagaagag gttgctaaaa tgtatgacta tgatattctt
    40021 ttagcgaata catactctga taaggaacaa gaacttaaga gtataaatct attgagagca
    40081 aaacaagtgg aaggtatagt tatgatttca tggatagttg aacaagaaca tatcaactat
    40141 atacaaaatt gtggaatacc agcgacatat ataagtaaaa ctgctagaaa ttatgatata
    40201 tatacagtaa gtactagcaa cgaagaagct acttttgata tgacagagca tcttataaag
    40261 aaaggtcatg aaaagatagc ttttataatg acgagtaaag atgatactgt tttagaaatg
    40321 gaaagacttg ctggttatga gaaagcactt tcaaataaca atatagaatt agacaagagt
    40381 ttgattaagt atggtggaac tgattatgag agtggataca atagtatgaa agaactatta
    40441 gatgatggaa taatacctca tgcggctttt gtaacaggtg atgaggctgc cataggtgct
    40501 ataaatgcta tatgtgatgc tggatataag gttccagaag acatatcagt tgcaggattt
    40561 aatgatgtta agatagctag aatgtataga cctaaactta ctacagtata tcaacctcta
    40621 tacgatatgg gagcagtagc aataagaatg gttataaaat taataaataa ggaattaatt
    40681 gaaaataaga aaatagaatt accttataga attgttgata gagaaagtgt cacagaaaga
    40741 aaaaaataaa actattaaaa tcaatcaggt agtgcctaag gcactacctg attttttatg
    40801 tcaataatat caaatttaat aatagattaa ctaaaaataa ttatctaatt acttaaatag
    40861 tttattttta tctattcatg agggttagac tttttagttt tcttaaataa acttttagat
    40921 tttttttgtt gactacctgg tgtatttttt ggtacaggtg aatttgactt acctttagta
    40981 ggtttagcct tcttagtttt agctggttta gtatctcttt ggttttctgc atctgagatt
    41041 ttttccatta tattatccag ttttttgcgt tgattttcat ctaaaaatgc tttgaatttt
    41101 gatactactt catctctgcc atctaggttc ttacctattt ttataagttc ctccataagt
    41161 tcattttctg attttccttt gtaactatca gccatctttt ctattttatc cttgtcaata
    41221 tttttttgtt tagccatttt ttctaatgac tctgtatcta attttttcat aaaaaaaccc
    41281 ctttctataa atatatattg aattatattc atactattta tatatagaaa taatattgaa
    41341 gtggtgaatt gtgagtgata tataatataa ataaaaattc ttatagataa tatatatgca
    41401 ctgagcttta aaaatggaac attaaaatat gaaaaacata ctttaatata gggcaattat
    41461 ataatataag ggggaattgt cttgaataac ttactatttt tgattggagt gattgcattg
    41521 agtaatggta atatctctat atttgatgat aaaaataaat caaaaggaaa taatagagtt
    41581 agaaaaaaca aaaaaaatgc aaatgataaa ctttcacagt ctacacatgg caatttaagg
    41641 tttgatgcaa atgatataaa aagaggttta aggctcatgg atttaagtga agaagattta
    41701 gaaatgggaa tggaaataat aacaagaact aaaaaataca tgtcaagaga tgaaagaaaa
    41761 atactaataa aaatagaaag tgttttagat ttagttagag gaataaaaaa attaaataat
    41821 atagatatgg tagatacaga agatgaaacg gattttttca gaaaaatgga tagtgatgat
    41881 aaaaagaata tgatgataaa ggaaattata gatgtattcc cagaaaaaag aaaaaattca
    41941 gttgaaaaag ctataggaat gaaaaagaag atagatttat ttgcagaatt atttttacca
    42001 gatgattttg gtgaaggtgg atttagtttg agctctttgg caaatataaa caatcttggt
    42061 agtatgaata atctcaaatt gttaggaagt cttttaagag gtgatgatag taataatgat
    42121 gatgaagaca ataatgatga gttaaattat gaagacgaag aattagattg tgaagacaaa
    42181 gaattggatt atgatgatga gttaacagat gaaggtgaaa tggaggataa tgaagatgaa
    42241 ttagtagaag ataagaacac aggctatgaa aatatagaaa atgatgaaga tatagtatac
    42301 gatgaggaac tatacaacat taatgagcaa gaatccgaat acaattataa tgaaaaaaat
    42361 actaaaacta gagctaagaa aaaacgataa ttaactaaat acataaagaa aaaaggaaga
    42421 aaaagtaatg atagaataag attatctcaa ttactatata aaaccacttt aaaaaattca
    42481 aaatttatta tataataata atatgaaatc ctgaaacata cgataaggct tttttaaatt
    42541 caacctacaa atgaaatacg ggagaccgtg tctggtaaat tataacatgc ctagttagtt
    42601 tggacgttaa aggttactgg caagtcaccc acctgggagt gcctagggtg tgaatttact
    42661 tagccaccgg tgtttcggga caaaaaaagt gctactattt caaatagtag tacttttttt
    42721 attaatatgc atttttctac taaatacgcc taattattga taaattcaaa aagcaagtaa
    42781 caattaagat tataaaagca tagtattaat taggcttcaa aaagccaaag acttaataag
    42841 aatcgcttac agggagggca atgaaaaatg caagattata aaaaaaataa aagaagaatg
    42901 atgaatcagc caatgtctac aatgaatgaa gaagaagtgt atacagatga aataaattca
    42961 gaagacatga gaggttttaa aaaatcacac catcataatg gatgtaatac tgataataag
    43021 tgtgagtgcc atgatgattg caatccatgc aacccatgta atccatgtaa acctaaccca
    43081 tgcaatccat gcaaacctaa tccatgtgat gacaattgtg gatgccatga caattgtaaa
    43141 tgtgattgtg aaccatgtga aatggattca gatgaatgtt ttgaaaacaa atgtggacca
    43201 gaatgctgta atcctatatc tccaagaaac ttctctgtat caaatgcagt gccatttgca
    43261 atagaggcta atagaatatt tgatactatg caattccaaa catttacaga tgcaacagga
    43321 ccaaatggag agccattaac ttttgaaaca gaagtagtag aagtatttgg ttcagttcca
    43381 agtgcaggtc aagcaagtgt aactatagaa aaaatatgct taagtaatga tggaatagtt
    43441 atagacacag gaatgacaac tttagaagat ttcgatttag acccattagg agatatagta
    43501 ggaagaaact gtgaaacaac ttttgaattt gcagtttgtg gagaaagaaa cgctgagtgc
    43561 tgtagacaag gaaaaggcaa atcagtagct tataaacaaa gaggattaac tgtagcagtt
    43621 cgtaatttag tactagagct aagaggtaga tgtggatgta cagagttcgt tgcattagct
    43681 ttcccagcag ttagagcagg aggtggatgt aagagaagag ttgattatgt agaatttact
    43741 tttaacacac tttcagcacc aatatgcttg ccagctgacg gaagagctgt tactttaaga
    43801 caagaatatc aaactaactt aactgtagat tgtataggaa aatctatatt aaaattagaa
    43861 tgcaacgaat gttgtgaacc tttctatgaa ttaattatac caaatgatat agatttagta
    43921 ctttgcttac aagaaacagt tagcacatta ataagtgaac aaatagtagt tttagcatca
    43981 ccaaatccaa tccaaccaag acttgttgat actttctcta aagtatgtga tttttcgcaa
    44041 tgtggaccta atcatggaag tggaaagcca agttgccaca gatagatagg taagatatat
    44101 agacagttta aattataaat aaaaaccatc taaggaaggc taccaaagtg tataatttac
    44161 attggtagcc ttcacgtttt tataactagc gtatagattt tagtgattta aaaagcacta
    44221 tagtatgtaa tagacaagta aagattgata ctatcgtcat tgtgtatatg tatgcataaa
    44281 tattaagtcc tggaattgga agaaatacat ataaagctat tagttgaatt aacatgccag
    44341 taatagtatt tatacttgaa gctaattctt ttcttattga atgtaaaatg ccagatagag
    44401 tttgatttag ggacataaat agtggaacta aaaacatagc ttttagatat tctcctgcaa
    44461 gtgtattttt aaatactaat atacataaat cttttccaaa gaaataaaaa aatattgatg
    44521 atagtatgcc tacaaataaa gtaagaagta tggagtattt gattttttta attacactct
    44581 tacgctttct tagagccatt tcctgtgaaa tagttggtat taaatttaca ataagcgctg
    44641 aaccaacagt aaaaggtaaa aatataaaag gcattaccat cccactgaca ataccataca
    44701 tacttaaaga ttgttgataa gtcattcctg ataatgctaa tcttgatggt atcatcatag
    44761 aacttataga ttgcaaaagt atgtttgaca ttctattaca agttatggga atagacattt
    44821 ttaatgtttc catagaagaa ttataaaaat cttttatgct tataatatac ctattgtcaa
    44881 atgatgaatc tcgccataag caaataagca taaatataat attactcaac tcaccaatcg
    44941 atatacctaa tagagctata taacaattca tagatttatt atttatgtac ataacaagta
    45001 aaaaaacaaa taatatttta ccaatttgtt caatgatttg tccaatagca gggattttta
    45061 cattctttat gccatagtaa tatcctctta gtacgtttga aagagttatt ataactatag
    45121 caggacaaac agctagtata aatagattta atttagcatc ttttaaaaat ttaagtgata
    45181 aaaaagaact attgaaagat gcaactatag atataattag tgctacgaaa aatgatatat
    45241 ataaagttga tataaataaa gcattagtat tgtgtctatc gtttaaagct tttctctttg
    45301 caactagaca actaagtgca gtaggtatac ctgttgttgt aacagctaag caaatcatca
    45361 aaaagttaaa aatcatatga tagataccta aacctgtttc acctagtgct cttgataaga
    45421 atattttata taaaaaacca aatattctta caataaaatt ggatataaat aaaataactg
    45481 ttgatagtac taaataaggt actttcaaaa aaatcacctc cttatctttt aaatatattc
    45541 acaaggaggt gtaaaaattt ataattttat aaattctggt ttcaatttat taaatttaga
    45601 tacatattta aatcccatat tttttagtaa tgaatatatg tagtcaaact cacatgcaac
    45661 ttgacttata tgatgtgaat ctgaacctgt ggttatgatt tcccctccca agtctttgta
    45721 catttgaagt atatacttag atggggttag gtctggaaga ttatatctat aacaagaggt
    45781 atttatctcg atacctttgc catcataaat agcttgttta agagtttctt caattatatc
    45841 agaaaatagt ctatcatcta aaatagtgtc ataaggtgcg taccttttaa tcaaatctaa
    45901 atgacctaag atagagtaat ctttataatt cttaacaata ttatataaat aaaggtagta
    45961 attttcataa acttcatgtt gagttttatc tttaaaataa ttaccaaggt ataagtccat
    46021 tgtatctata gcatggatag aacatattat aaagtccaat ggatattgat gtgcttcctt
    46081 tttgtatgta tccattaatt gagtttgaac tccaaattca attccttttt ttattgatat
    46141 tttatcttta tatttgcttt gaagagtctc taaactctta aaataatctt catagacaat
    46201 tgaaaaagaa tcatcagcat atacatcata gtcaacatgg tctgtgaaac aaatttcctc
    46261 caaaccgagt tcaatagatt tttttaccat ttcttccatt gtagattttc cgtctgtaga
    46321 gaaacttgag tgcatgtgat agtcgtaaaa cataaatatt tccccttttt ataaaaattt
    46381 tggtattata tatacatact aaataatatc aaatatacat aaaagcatca ataaaatata
    46441 aatacaatga gcggtgataa atttggaaaa atacagaata gatttaaatg agaaaaaatc
    46501 aactaaatat atacagatat ttaatcatat aaaagaattg ataataaata aagagttagt
    46561 agaacatgaa aaattgcctc caataagaaa actatcaaat tttttacaag taaataacac
    46621 tactatagtt aaggtatacg agcttttaga aaatgaagga tatgtatata aaattatagg
    46681 gagtggtact tttgtatcaa gtttaaattc ttataaaagc ggtatagata acaggaaaaa
    46741 taagattatt gtgcaaagag aagatttaat tcattttgac aatgggaatc catctaatga
    46801 tatgtttcct atcgattcat ttaaaaatgc tgtaaatatg gcattatcta aagatggtag
    46861 ttcaatattt gaatatgatg aaggtcttgg ctctgaagaa ttaagagaaa aaatggtaga
    46921 gtatctaagt gatggaaata taaaaactac taaggaaaat attcaaataa tatcaggtgc
    46981 tcaacaaggt atagatatag tttgtaaagg acttataagt tactcagatg ttgtttttat
    47041 ggaagaacct tcttacaatg gagcaattga agtgtttaaa agtagaggtg caaaaataat
    47101 atctatacct atgttagatg atggaattga tataggtatt ttaaaactaa agttggaaaa
    47161 aataaaacca agacttatat acattatgcc taattttcaa aatccaactg gaatatctta
    47221 ctcaacatat aaaaaaaaga aattgataga attggcagaa gaacatgatt tttatataat
    47281 agaagatgat tttataagtg attttgtttt tgaatcaaag gacaatagaa caattagaag
    47341 ttatgatgat aaaaatagag ttgtatatat aaaaagcttt tcaaaaatac ttatgccagg
    47401 tcttaggata ggaattgtag aaatgccaaa tgagttgtta aaaaaagttt tatgggctaa
    47461 atattcatca gatatatcaa caccaggttt aattcaaaaa tcaatgtatt actatatgaa
    47521 taattttgat tggaagaatt atttgagtca tatagagaag atatatactg ataagtataa
    47581 attggcaaaa aacttgatta atgacaaatt gagtggtaaa ttaaaagtta gaaaatcttg
    47641 tggaggaata aacttttttt tagaattacc aagaggatat acatctcaag catttacaaa
    47701 ttttatgtta aacaaaggag tgtcaatgct tccaggaact tatttttttg acaatctagt
    47761 ggatgataga ttctttagga taaatatagc tcgtccaagc atggaagaac tagaaaaggg
    47821 aatatctata ataagtgata atatagatga gtttttttgt gaatataaaa acaagttaga
    47881 tataaaaagc aataaattat tttattaaat aaatagaggt tttttaggag gaaaaaatgt
    47941 ttgacaagaa gaaattagat aggattaatg aattagcaaa gaaaaataaa gagggaatcc
    48001 tttctgctga tgaaatcaaa gaaagagaaa ttttaaggaa agaatattta gaaaacttta
    48061 gagcccactt tagatcaaga ctagatagtg tcaaagtagt ttcaccagaa gaatatgagc
    48121 aatacatgaa aaacaataaa aattagaact tagtaggagg aaaatatgaa cttaaagtac
    48181 gaatttaaga atgcttggga ttttgaaaga aaagaaaata ctattgaaca aattatgcaa
    48241 tattctcgca attatatgga gtttttaagt aagtcaaaga ctgaaagact ttcagtaaaa
    48301 gaaattataa aattggctaa agaaaataac tatatttcaa tagatgaagc tatggaaaaa
    48361 ggaagtataa gttgtggtga taaaatttat gtcataaata aagagaaggc agtagcactt
    48421 tttgtaatag gtaaaaatta tatagaaaaa ggtatgaaga ttataggaag ccatatagat
    48481 tcgccaagat tagatttaaa accaaatcca ctgtatcaag agagtaatct aggttttttt
    48541 aagactcatt attatggtgg aataaaaaaa taccaatgga cggctattcc acttgcttta
    48601 catggtatag ttatattaaa tgatggaaca aaagtggaca tatctattgg ggaagaagat
    48661 agtgacccag tattttgtgt aactgattta ttgattcatt tggctggaga ccaaatgcaa
    48721 aagaaactat cagaaggaat tagtggagaa gctttaaata tattaattgg gaatattcct
    48781 ttagaagatg aagaaaaaga acctataaca gcaaatatat taaagatttt aaatgagaaa
    48841 tacaatatag ttgaagaaga tttattaagt gctgaaattg aagtagttcc agctggtaag
    48901 gctagagatt tagggcttga taggtctatg gtattgggat atgggcatga tgatagggta
    48961 tgttcatatg ctgctgtaaa agctatacta gaaactgaac aaccagaatt tacttcagtt
    49021 gcattatgtg tagataaaga agaaattggt tctaaaggga atacaggtat gcactcaaag
    49081 ttttttgaaa atactgtggc tgaactgatt gctttagaag gagattattg tgatattaaa
    49141 gtaagaagag ctttagcaaa tagtaaggta ttatcagctg atgtttctgc tggatatgac
    49201 ccaaattttg gagaagcata tgaaaagaga aattcggcat atatgggaaa tggagtagtt
    49261 ttaactaagt atacaggttc aagaggaaag agtggatgta atgatgctaa tgctgaattt
    49321 atgtcagaag taaagagaat ttttaataaa ggaaatgtag tatggcaaac tgctgaactt
    49381 ggaaaagtag accaaggagg aggcggaact atagcccata tattggcaaa tcaaggtgca
    49441 gaggttatag actgtggtgt tggagtttta aatatgcatg caccacatga gattgtctct
    49501 aaagtagaca tatatgaaat gtataaggga tataaggcat tttttaatat aaatttataa
    49561 gtaaaaatat aaatgtaata agtgaataaa ggctgttgta taaacaattt aatctgttgt
    49621 acaacagtct tatttttatg taaaaatagc aatttgtcac actagagaaa ataaaagaaa
    49681 atactgtcaa attaaaaatt atttaaaaaa aaattgacaa cgatttcatc ttgttataat
    49741 atgtaataaa gaacttgtta tataatgtta taaaaatgtt acatagggag gtgagcaaaa
    49801 tggatgaaaa gagacaaaaa aaagaaatgg atttagaagt aaattccttt gttcctttat
    49861 atcaacaact atatgacaac ataaaaaaac aaatagcatc tggcatatat aaaccaggag
    49921 ataaacttcc atctgaagga gacttatgta aagaatttaa tataagtcgt ataactgtga
    49981 gaaatacgac ttttttatat aaaatagcaa aataacagtg tttgagcaaa aaaaaagaat
    50041 gttttttatc gttttgccac ctgtttgcca ccataacttt tttcggtggc aaattattgt
    50101 aaaatgccct ccaaaatatc tattgtttca ctttccattt tacttgtaac atgtgaatat
    50161 gtgtccatag tggttgataa ttgactatga cctaatcttt gttgtatata ttttacatta
    50221 gctccatttt ctaataataa tgtggcatgt gtatgtcgca agcaatgaaa attaaagtta
    50281 atatttagtt tcttgttaat agttcttata gcagcgtcaa tattgttgtg atttacaaat
    50341 gagccatctt tttttctaca aacccaatca tactcagttt ctttatacca ttttccaatt
    50401 ttaatttttt gttttttttg attcaatttt tcctctttta atatcctaga caaagtatca
    50461 cctattttaa tatctcttat tgatgttttt gtcttaggtg atgctaattc aaattctgaa
    50521 acttttctct ttattaaatt ttttctaact ttgattatat tattatctaa atcaacatta
    50581 tcccaacaaa gacctaatat ttctcctttt ctcatgcctg tatgaaaccc tataagtaga
    50641 ggaatataga tatttgtatt tttaggatat atttctagta ttttattgaa ctcatctagt
    50701 gttatagtct tgttatctga ctcatttttt acctttaaaa cattttttgg tatactggca
    50761 tattgaacag gattttcctt aatgagtttg taagggtaaa cagcagattt taaagcagca
    50821 tttaatacaa cataaatcgc ttttaaaact ccttttgtgt agtgtttttc ttctccgttt
    50881 tgtgtgtatg tctcttttga tttattattt aaaaattctt gaataatagc tggatttata
    50941 gattttagct tacatttacc aagtctaggt tctatatgat tttcaattaa atttctataa
    51001 ctttcctgag tattgtattt gcaattaaga agtacatact ctttgtacca aaagttaaga
    51061 tagtctgata aactcatatt tgtttcatca aacactatac cagcattttc atattcattt
    51121 attgcatcac ggagcgattt ttcagcttct ttcttagtgt ttccaccaac tctttctacc
    51181 ttttttctct tgccatctac tatacctgca tcaaagtagt aataccactt ctttccacgt
    51241 tttcttacgc cgcctttcat aaaatctctc ctctcaaaag ctttttttat gtaattatat
    51301 aataacatat atcaatttaa ataaaataaa taaaaaagac tataagaaac aaagttttat
    51361 gtttataatt aatagtcttt tttatttaga tacatattta atgtttttta tcacgtgatt
    51421 ccagcacttt ttctgccaaa taaacaacta ttttttcata ctcaatatca gtttctaaag
    51481 aaaagtcaac aatagcaggt atcgtcatat ctcctgcata tttattacct aaccaatttt
    51541 caattaattc caattcttct ttgcttaatt caaatttttt ctttttatta aaacttaagt
    51601 tcaatttatt cacctcaaat aatattatat attaaaaata gtatttgata gaaacattcg
    51661 aattatttat gtaattttct ttttttaata tattcatcag caaaataatt tactaaatat
    51721 ttttcctcca atcctaaagc tatttctaat tcaataagag cagggatagt taaatcttta
    51781 ttctcattat tttccaacct agaaatttga cttctgtggc aaccaactct ttttgctaac
    51841 tctatttgtg ttaatttctt cttttttcgt aactctttta acatatattt aacctacctt
    51901 ttagataatt ttatatatgt tagtttgtgt aatttcttgt aataaatgtg caatattcgc
    51961 acactttttg ttggaaattt gtgctagaat gtagttaaga aataacttta tctagataaa
    52021 gcaaaaataa tagaagctat aaaatataat aatattttac agttatttta tagttttaag
    52081 ctttgaaaaa gaggtggttg taactatttt taagaacgta tgtttcgtgg aattaataaa
    52141 taaaatattt tataggggat gatatatttg aataagacga aatattatga tattttaaag
    52201 ttaaacttat taatgaaaaa gttgaaagaa ttggataaaa ataaaatcaa tgaatataaa
    52261 ataaaagtga aagaaataca taaaatcaat aaaaaagagg aatgattcct cttttttatt
    52321 atattcattt tcagaaataa actatttttt atttttttcg tctagtaaaa ataattctgc
    52381 aacttttaat gctttttctc ttgcgtctgg gcttagctcg ctaaatatat taaaaacttc
    52441 tttcatatct tcgtcaagat acatattctc aataagctcc ttttctgttt taaaattttc
    52501 agcatcataa tctttttcgt ttttatttat aaataagcta tttctaacat cagttcttcc
    52561 taataaataa tctgtagaca catcaaaata gtttgcatat tcttctattg tacttttctt
    52621 aggttctctt aaaccatttt ctatccttga tagtgtagat ttgtttatat gtaaatcctc
    52681 gcttaatttg tctagcgaga tgcctttttc ttctctcaat tcttttatcc tattcaattt
    52741 gcacaacccc tttttatatt aattccaaaa tagcaacttt tatttatatt atagcaacaa
    52801 aattaattat tacaattttt tttgctaaaa aagcaacaaa agtattgact ataatcacaa
    52861 aacttgatat tatataaata tgaagttgcc aaaatagcaa aaaggaagtg atttaatgta
    52921 cttaaataga ttagaaggat tgatgaagga aaatagacac acccaaaaaa atgtggcaga
    52981 tatattaggt cttagctcat atggttttag attaaaatta aaaggaaaaa acgaatttaa
    53041 agcaagtgaa ataaaaaaga tatctaaatt atataatgta tctgcggatt attttttttc
    53101 agatgaagtt gctaaaatag caataaaaga agaaaggggc aataaataat gaagaatcta
    53161 accataatca agcaaaataa tcaattttta gttgaaagta gagaagtagc agaattaata
    53221 gaaaagaagc acgataattt attaagagat ataagaggat acaagaagat tttagaggac
    53281 tcatcaaatt tgaagagtca agatttcttc atagaaagta cttatataaa tactcaaaat
    53341 aaaattcaac cttgctactt attaactaaa aaaggttgtg acatggtagc taacaaaatg
    53401 acaggagaaa aagggattat atttacagcg atttatgtaa ctaagtttga agaaatggag
    53461 cgagagttaa aagaacagca acctaaacta ccaactacgt acaaagaagc attgcaacag
    53521 ttattaatag aagttgaaga aaaagagcaa ttacaattag aaaatcaaga aaaagataag
    53581 gtaatccagt tacaacaacc aaaagtactg tttgctgatt cggtagcatc ttctgacaat
    53641 tcaatcctaa ttggagaatt agcaaaattg cttagacaaa atggaattga tacaggacaa
    53701 aatagattat ttgactggtt aagaaataat ggttacttaa taaaacgtaa aggtgaggat
    53761 tacaatacac caactcaaaa aagtgtagat ttaggagtta tagaaacaaa agaaggtaca
    53821 agagtacatc cagatggtca tacaagtatt actaaaacac ctaagattac tggtaaggga
    53881 caaatatact ttattaataa gtttaaaaag aacaatcaaa tatcaatgtt aggttaaaga
    53941 ttaatagcac tttgaaaact aaatacagaa tattttgaaa aggaagtgat tacatgagta
    54001 ataaaaagaa atatactttg agtattacag aagaattata taataaatgc aaagaaaaag
    54061 ctaatcaaaa aggtatgtca gtaaatgagt acatactatt agtgattagc aagaatttaa
    54121 aaaatattta atttttatta acttaaacat taattttgcc atttattttt tcataacttt
    54181 caacatgttt tttaattaat tgttctattt ctttgttggc agaacgacct tcactttcag
    54241 ctatatactt gattttttca agtagattgt tatctattct aagtgtgtat ctcggtaatt
    54301 ttgatggcat aaatatagca ccctccttaa gtctaaatga tgtcactatt ataccacgta
    54361 aattatttca aaaaaagtgt tgacgcaaag gtgacgcaat gataatataa taaacaagga
    54421 ggtggttcaa aagtgacggc aaagaagaga gtaactgtta gaatgccaga cgaattaaat
    54481 gaagagctac atagacaatc tcaaagaaaa ggattaagta aaaatgcttt tataataaat
    54541 atcttatgga aagaatttga ggatttacag gacttaaaag atgaacagga ggttgataag
    54601 tatgaataac ttacaaatat ttgaaaagat ggagtttgga caaataagaa tggcagagat
    54661 tgataataag ccttactttg taggaaaaga tattgcaaag tcattaggtt ataaaaatac
    54721 caatgatgca attttaagac attgcaaagg ggtagtgaaa cacgaggggt ttaaaattaa
    54781 tggtattaag attgctttga taactgaggg tgatgtttac agattaatag taggttcaaa
    54841 tcttccaaac gcagaaaagt ttgagagttg ggtatttgat gaagtgcttc caactattcg
    54901 acaaactggt caatatcaag cacaacaaaa tgtaataaca gaacttacag gaactatagg
    54961 agatttaaaa ggaacaataa aagaatataa aaagttgtgt aagataacat gctctaagaa
    55021 acaacagtat tctaaataca taaagaatag actggatata gacaaagcta ataaagaata
    55081 caaccaagtg aaagcaaggc tattcctaat tctcggagtg gagaaatggg aagatataga
    55141 ctttgacaca tctaataatt taatacaaat tatagatgat tgtataaagg ttataaagtc
    55201 agaaagacca tacaagcagt tgagttattt tgagaactaa atacagaata ttttgaaata
    55261 tattgtttta attaattatt aactaggagg ttaaatacat gaaaaataat acaagcgatt
    55321 caagagtaaa atatttttgc aaatgtccat actgcgggtt tgataatgag gtagaagtta
    55381 aaaaagggtt gaagcctaag atatgttgca tatgtacaaa agaagttgag tatgaaaaac
    55441 tggagcaaca aagtgctttg gaaaataccg aaattaaagg agtgtgtaat caaatgaaaa
    55501 ttaaaaaatt agcactagca acaggagaag tatttgaaaa catagagctc aaagaatttg
    55561 aaaataaagg agaatgctta ccatcaaata tggtaaaggt tattgatggt aagcaggaac
    55621 ttctaataaa taaagagttc atattatcat tagaagtcaa aagaaagact actttttagg
    55681 tcctttctta gtttgtgaca gagcactacc agcaaccgat ttggaagcag cactatatct
    55741 tccgtcttta agaatcttac tagccttaga agcaacagtt ttacttgttt gtttagtatt
    55801 tttagctata ggtatcacca cctttaaatg tatttatagg atatatccta caaatatagt
    55861 atatcaaagg aggaaaataa tggcaattaa tgacaacata aataaaattt taaaagatag
    55921 agatttaaaa gcatggaaat tagcaaaaga aataggtgta gattcaggga atttatatgc
    55981 aattttaaga ggagaaaata aaaatccaac tatagataca ttaataaaaa tagccgacta
    56041 tttagacatt acattagatg aactagttgg aagataaaaa ttaaatacag aatattttga
    56101 aaaggagtga gtaaattggg caatatatct aatttcaatt tagataaaca agaagataaa
    56161 agttttaatg acctagataa tatatcaatt tgtttttcag aaggtatccg taaagttgta
    56221 gaaatgaatt taaacaacta taaaaataaa atctcaaagt acttaaatga aacttcgaaa
    56281 atagaattat tagaaccaaa agaactaaca attgttataa gtaaaggtta tcccgattat
    56341 cttatgtctg ttgaagaagc aagtaaaaga ttgaaaatag ataaagtatt tggatatgag
    56401 ttaataaaaa atgggctttt gaagtcagtt gatatagggg caactaaagt ttctagttat
    56461 gaattagatg attttataac taggaatcaa ggaaaaaaca tcaaagaaat gcttagagaa
    56521 atgaaagaac ttagagaggg ggtgatttaa ttggaactag taacatacag aaacaagctt
    56581 gttttactaa aagatggaga aaagattgca actataagtt taaaaaggaa atttctcagc
    56641 aacagactta aattaaaaat aagataggag agataaattg aaaataattt ataaaaacaa
    56701 agtttacaaa gtagaacaag acaaaaagtt atttagaatt acatactatg atgagcagag
    56761 aggtagtaag aagtttaata aagagaagaa aataaaaaga agtgttttaa caagagatat
    56821 agagttagtt aacttgtatt taccagcaca tttaaaaata aaataagcta taaataatta
    56881 aagaaaaagg tgattagatg gaaatagaac aagcaacaat acgcctgcct agagaactta
    56941 aagacaagct tctaaaacag gcaaaagtta aaggatatac attaaaagat atgatagttt
    57001 ttattctaaa ggattatctt caaaatattt ctcaagaata aattcaattt ctctacctat
    57061 agaacgctta tctttttgag caagttgttc gattttctca aaaagaagtt tattaattct
    57121 tagtgtaaat cttttatcct cttcacgagt ataaatatct ttattagaca tatttatcat
    57181 tcctcacata aaatttgacg tctttatgac actttaataa taaaataata taaaagaaaa
    57241 gtcaacaaaa atgcttgacg tcaaatatat gacatggtat tattaaaaca agaagggagt
    57301 tgacgtcaaa tatatgacaa atgaaagagt tagatttaca tttagattac cagcaccatt
    57361 gcttgaaaaa attaaaaata gagcatcaat agaaggtagt tcaatgaact cacttatatt
    57421 acacatactt tgggattaca taaaagaaat agaaaataag gaggtcaaat aatggttgaa
    57481 ttggtaaaag aatttgattt acaaacaatt aaagtaggaa atgcagtaaa agtaaattgc
    57541 aaaagatttg gttttgaaat tgattgtata gtagtagtag caacagaaaa agaattaaat
    57601 ttagcatact ttgatgaagg tagaggctgt atggagtatc aagccttaat aacagaagat
    57661 attcaagatg gtgattatga gattaaaatt ttatcttagg aggaaataaa atggctgctt
    57721 taataatggt aggtttattt gcaatatgtt tagtaggatt agttcaaaat agagattaaa
    57781 ttaaggggga ttaattatgg aaagtttaaa aagaataaaa aaaatggttc aaaaacaatt
    57841 agttttagct gaattagaga taaacaaaaa tagcaaactt tatgaggaac ttgaaaataa
    57901 ggatagaggt ttaatagatg atatacacat gagagaatat ctaagagaaa aagttgcatg
    57961 ggaaagagta aaatatgcta ttgaaaatat tttaggtggt ataaatttag agattaaatc
    58021 aaaggaacat gaagaaagtg aggattacaa gatatttcaa ttaattttag aagaacttga
    58081 aagagataaa cctatagatg ttcagatata agaaaagagc cattgccgtg gctcaattca
    58141 aataaatata tcaaaattta attaagctaa ttatagcaca aacggaggga aattatgagt
    58201 actttatatg aattaactac agatttatta gaaatagaag aaggtttaac agaaacaaca
    58261 ggaaatgaaa ctgaaaaact agaggaaata aaagaaataa taaaacaaga gatacaaaat
    58321 aaaaacacta ggatagtttc agtaatatta aacattgaca gtgatataaa ctctatagat
    58381 tcagagatta aaagactgca agagttaaaa agggtcaaaa agaatactct tgatagatta
    58441 aaaagcaata taaaagactg tatggaatta cttggtacta aaaaagtaga aacagtttta
    58501 ggaaatataa gtataagaaa gtcagcaggt agcttagtca tagaagatga agaaaagata
    58561 cctgctatat ataaaacagt agagcaagtt gtaaaagtag ataagaatat cattaaagac
    58621 tttattaaaa aaggtcatga ggttgaaggt tgcaggattg aatatggaac tacactaaca
    58681 attccaaaag ctaaaaaaga gtaggtgagg accatggaaa ctaataatgt ttatataaaa
    58741 cttgt
//
LOCUS       DAEORM030000020        58544 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.020, whole genome shotgun sequence.
ACCESSION   DAEORM030000020 DAEORM030000000
VERSION     DAEORM030000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 58544)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 58544)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 58544)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..58544
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.020"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            127..1755
                     /gene="aspD"
                     /locus_tag="KRH23_001692"
     CDS             127..1755
                     /gene="aspD"
                     /locus_tag="KRH23_001692"
                     /EC_number="4.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047688 - aspartate 4-decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0006531 - aspartate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate 4-decarboxylase"
                     /protein_id="HHS5224972.1"
                     /translation="MKNHTYKEIKNIYGKISPFEFKDKLIDIAKYTAKENNRELLDAG
                     RGNPNWTCSTAREAFFTFGHFAITETRSNWDLGHLAGMPQKKGIKERFFKFINENIDM
                     PGAYLARDIINFGINELGFDGDEFVHELADGIIGDNYPLPDRMLPHMEKIVHDYLVQE
                     MKYDISGKYGDVEIFAVEGATAAMCYIFDSLMANELLKKGDTIALMTPIFTPYLEIPN
                     LPRYDFKVVNINANEVDEKGAHTWQYTKKELEKLRDKSIKALFVVNPNNPASIAMDET
                     SCNNLIDVIENYNKDLMIISDDVYGTFVEDFSSLMSKLPYNTVGVYSYSKYFGVTGWR
                     LGTFALHKKNVFDKKINDLTGELKKSVDKRYSDMSLNPSSLSFMERVVADSRLVALNH
                     TAGLSTPQQVQMAFFSAFALIDKVDAYKKLNMSICHRRQKLLFEALELPINENKNNAA
                     YYTQFDIEEWAKLNYGEDLFKFISKTASPVDVLYKLANDYSVVLLSGNGFYGPEWSIR
                     ISLANLYDEAYTKIGKAIREILNGYIVEWQKIKK"
     gene            1876..2871
                     /locus_tag="KRH23_001693"
     CDS             1876..2871
                     /locus_tag="KRH23_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HHS5224973.1"
                     /translation="MSIKKKVAIVFTGGTISMTVDDKVGAAIPTLSGEQILSMVTNID
                     KVADVEVFNFDEIPGPHITPYRMMELKNYVNDLLARKDITGVVITHGTDSLEETAYFL
                     DLTIDNIKPVIVTGAMRSSSELGYDGSSNLSASVCTAVSKDAMGKGVLVVLNNEVLLA
                     SEATKTNTLSLNTFKSLTSGPLGIIDCNELVLTRDIVNRTIIDTDKVESKVALFKAYV
                     GENADFIRFAVDSGYKGIVIEAMGRGNIPPQMLSGVEYAREKGLPVVIVSRCHSGRVF
                     DSYGYFGSGRDLKNLGCIFGGDLPGQKARIKLILALGKTDNLDEIKDFFEKGIYC"
     gene            complement(3049..3432)
                     /locus_tag="KRH23_001694"
     CDS             complement(3049..3432)
                     /locus_tag="KRH23_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HHS5224974.1"
                     /translation="MLNKKLPDAELKIMKYIWNTGYKTVISKDVADEIEKTYAWKHTT
                     IITLLARLTKKGFFISQRIGKHVHYRVLIKEKEYLKIEGKRIFGGLHNNPLSELISKL
                     HDGEEITEEKIIEIGNWIKSWKDED"
     regulatory      3659..3756
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     repeat_region   3898..4454
                     /inference="COORDINATES: alignment:CRISPRCasFinder:4.3.2"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=3898..3926
                     /rpt_unit_seq="gtttacattccacatagttaatataaaac"
     gene            complement(4740..4898)
                     /locus_tag="KRH23_001695"
     CDS             complement(4740..4898)
                     /locus_tag="KRH23_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA];
                     GO_function: GO:0090729 - toxin activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin"
                     /protein_id="HHS5224975.1"
                     /translation="MDNFLQGILASLSASLIVYIASKLFRKRKKPLKAATKSGWEFDL
                     KIRFHKTK"
     gene            complement(5257..6627)
                     /locus_tag="KRH23_001696"
     CDS             complement(5257..6627)
                     /locus_tag="KRH23_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp29"
                     /protein_id="HHS5224976.1"
                     /translation="MKLKKLLSLGLVSMFVVGFPISANALDKIDKIQGADKYETAGII
                     ADKQSYTTAILINADSTMADGLSASGLAGATNAPILLTKKNNIPNATLKRVEKAKKVY
                     IIGGESSIDKATETFLKDKGIEIRRLQGNDRIKTSYNVAKEINSINKANKVILTNAFK
                     GEPDAMSIASVAVRDKAPIILTDGKSVPFNTTGIESYAIGGTSSMSDSLVNDTNSTRL
                     GGVDRYDTNKKIVNKFYNGAKEFYIASGTDLVYALVGSPMAKNNPIVLVDIGSNKDIL
                     KNAAKVTGIGNLSDKIMLECENTINNISLPSSNKNIICGLKIDFDSNHIIWQDKGSYL
                     ECYDDNLEYYTEKYKDPTVPINIENTSTQNLDVTKLKVYGEANSTLYMGQYAKIKMDF
                     NSFGVLKPGEKCTIYLDIISLDPSRSMTLTFSYVGDKENYKYEQGLASRILFYNPDGE
                     DFFEYK"
     gene            6841..7959
                     /locus_tag="KRH23_001697"
     CDS             6841..7959
                     /locus_tag="KRH23_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HHS5224977.1"
                     /translation="MNIKSAFIRKRGEKFYVYVEYIEETTGKIKQKSYGSYEKKKDAE
                     KHLIEIKSTINNNKFVAPKDMTFVERCYKYIDMNKNNWSPYTVTNTKSWVKNYIEPFF
                     KNLKLTEVNPSSVQAFVNYNFNNSTFTSAKVRYSFLSSVIREAYRLREIQENSCDFIK
                     LPSKEKYSTNEIYNREEVLLLIEKLLGNNIEIPILLMLLLGLRMGEATGLRWSDVDLD
                     NNLINVNQILVYSNGKISFKEPKTPKSKRALSAPKELIEKLKIEKLRQSKLKLQGILE
                     NKNNLVCLNTNLNPFLPSSLRKTFHNFTKKNNLKKIRIHDLRHTSATLLLLGGTNMKV
                     VSERLGHTDIKITMNRYSHVLKEMDKEASDNLSELLFK"
     gene            complement(8276..8944)
                     /locus_tag="KRH23_001698"
     CDS             complement(8276..8944)
                     /locus_tag="KRH23_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA];
                     GO_process: GO:0046677 - response to antibiotic [Evidence
                     IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HHS5224978.1"
                     /translation="MEIVTNNQSGVEIQLSLFEAIKDLLLINPIFLLGIILIGIFLVV
                     IFKKNSDIPKVKTSILSLAMYYYLCLTLSHIVGIPTFSEYIRLSQLGETFFNPNINLI
                     PFSDGFSLSFILNILLFVPLGFLCPLISKTFERLRNTFLIGFGLSLFIETIQLFTLHR
                     ATDIDDLLTNVIGTIIGYFCFKLIAKLRIVKLHSDDDSMEQDYTVCIPIAIIIVALIL
                     GFFS"
     gene            complement(9040..9171)
                     /locus_tag="KRH23_001699"
     CDS             complement(9040..9171)
                     /locus_tag="KRH23_001699"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224979.1"
                     /translation="MVASGDMERNQFIDMVTIFLSNLMKESQEYHTEVRQELTGGIN"
     gene            complement(9795..12215)
                     /gene="leuS"
                     /locus_tag="KRH23_001700"
     CDS             complement(9795..12215)
                     /gene="leuS"
                     /locus_tag="KRH23_001700"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004823 - leucine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006429 - leucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HHS5224980.1"
                     /translation="MSVYNFKEVESKWQKIWKDNNQYKMDTAQTEKPNYYTLEMFPYP
                     SGKIHMGHVRNYSIGDVVARFKKMEGYNVLHPMGWDSFGLPAENAAIKHGIHPHKWTM
                     ENIEEMKEQLNLLGISYDWDKEVATSTPEYYRFTQEIFLKFLEHGLAYKKKSYVNWCP
                     SCETVLANEQVVQGACERCKATVLKKDLEQWYFKTTEFAEELLNDLDTLDGWPEKVKT
                     MQKNWIGKSTGADLVFDIDGTDKSMTVFTTRPDTTYGVTYMVLAPEHELVKELVAGTE
                     YEADVEAFVQKMHTMTEIERTAADVEKEGMFIGRYVINPLNGKKVPLWIANYVLVEYG
                     TGAIMAVPAHDERDRDFAEKYNLDIIDVITEDNKMINSEEFNGLDASEGFEGIIDKLE
                     KEGRGKRTINYRLRDWLVSRQRYWGCPIPVVYCDECGIVPVKKEDLPVLLPTDVEFTG
                     KGESPLTTSKQFMSTTCPHCGKPARREVDTMDTFVDSSWYFLRYVDSNNENEPFSKEL
                     VNRWHPVDQYIGGVEHAIMHLLYARWFVKAFKSMGMVDFNEPFKNLLTQGMVLMDGSK
                     MSKSKGNTVSPMDIIDEYGADTARLFVLFAAPPERDLDWSEQGVDGCFRFLNRVYRLV
                     DELADVVKKDVEFGELNSQDKDMRYTIHSTLKKVTADLSEKFGFNTAISALMELINDM
                     YKYKELDNINEAVIKEGVQTIVTIIAPFAPHLGEELWTMIGKEGSVFDIDWPKYDEKA
                     LVKDEIEVVVQVNGKVRGKLTVNSNISKDEMEKVALEDEKIKGLVEGKTIVKVVAVPK
                     KLVNIVVK"
     misc_binding    complement(12324..12516)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(12569..12919)
                     /gene="rsfS"
                     /locus_tag="KRH23_001701"
     CDS             complement(12569..12919)
                     /gene="rsfS"
                     /locus_tag="KRH23_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0017148 - negative regulation of
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HHS5224981.1"
                     /translation="MTVEQMTKIAYDAIEDKLGQDTVIINIGKVSSLCDYFIITTASS
                     QRQVKAIADNVEDELSKLGLEPRGKEGQGTQTWVLLDYGDIMVHVFNEENRGFYNLEK
                     LWKDAPYIDIDTLA"
     gene            complement(13036..13608)
                     /gene="yqeK"
                     /locus_tag="KRH23_001702"
     CDS             complement(13036..13608)
                     /gene="yqeK"
                     /locus_tag="KRH23_001702"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HHS5224982.1"
                     /translation="MNLENINQRLNQMLPVGRLSHSKNVAKCAEKLCEIYGCDKEKAY
                     LAGMIHDCAKYLSDKEIEDYVNKYEIYLDPIEDGNRSLSHSVIGAYICEYEFEVEDED
                     IINAIKYHTTGREDMSLLEKIIYIADLIEEGRKFPVVDTLRELAYGGKLDEALLTSFN
                     NTLMFVINKKEEIHPRTVMARNYLIKEKLL"
     gene            complement(13609..14298)
                     /gene="nadD"
                     /locus_tag="KRH23_001703"
     CDS             complement(13609..14298)
                     /gene="nadD"
                     /locus_tag="KRH23_001703"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HHS5224983.1"
                     /translation="MRSENLVKMAELKNTEKLEKFNRHKGKIKIGILGGTFDPIHYAH
                     LATAEFIRDKYDIDKIIFIPSGNPPHKLCITTDKYDRYNMTLLATESNEDFLVSKVEI
                     ERKKRTYTIDTLKYLKKKYKNADIYFITGADAICSVEEWKDVKKNFELATFIAATRPG
                     ISLLRSQETIEKLTKKYNADIITVYVPSLDISSTYIREQLNEGKSIRYLVPENVENYL
                     YENKLYQYGDD"
     gene            14574..15212
                     /gene="recX"
                     /locus_tag="KRH23_001704"
     CDS             14574..15212
                     /gene="recX"
                     /locus_tag="KRH23_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HHS5224984.1"
                     /translation="MGIITKIEQQKRNDDRVNIYVDDKFFIAIFKELVYTFNLKKGNE
                     INEEELKPILDDEMYIKAKNKALNILSHADQSEKKLKEKLSSEFDENIIERVIDFLKS
                     YNLVNDSVLAQKIVNTNVNLNKCGKNRIKQNLYNKGINRSTINEAVSELDKDTEFENA
                     MYLAKKRYERVKKEDKKKIYQKISQHLSYKGFDYDIIKRVLNKLLNFDEYDI"
     gene            15365..17368
                     /locus_tag="KRH23_001705"
     CDS             15365..17368
                     /locus_tag="KRH23_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase family glycosyl hydrolase"
                     /protein_id="HHS5224985.1"
                     /translation="MKSQKRFKILDIDVYLQPFESDIKKRMKHYEDMKSKTLKNYKDF
                     SSFANAHLYYGFHQTNDGFFYREWAPNADSLSLIGDFNNWNRKSHPLRKIGSGNWEIF
                     IPGQNSLPHKSEVKVQVTANGKTFDRIPLYIKRVIQKDFGGFNGQIWQPKTPFIWTDN
                     NFDLKNITSPLIYECHIGMSTESESIGTYNEFTEKILPKIKKAGYNTIQLMAIMEHPY
                     YASFGYQVSNFYAISSRFGTPEDLKNLINTAHSMGIAVLLDLVHSHAVKNTLEGINEF
                     DGSEHQFFHSGSKGNHPAWGTKLFNYGKPEVIHFLLSNIKFWLNEYHFDGFRFDGVTS
                     MLYHNHGLGVSFDSYEKYFSMNTDIEAITYLQFANELIKEIKPNSISIAEDMSGMPGM
                     CIPIKDGGIGFDYRLAMGVPDFWIKTISNLSDEDWDLGKMWYELTTRRPGEKNIGYCE
                     SHDQALVGDKTIIFWLADKEMYWNMEINSNNHVINRAMSLIKLIKLITFSLAGEGYLN
                     FMGNEFGHPEWIDFPREGNNWSYKYARRQWSLSEDNNLKYKQLLSFDKSMLELTKYSD
                     IFIQNSHELIHMDNDKKILVYSKGKYLFIFNFHPNLIQSVDISKFQNTNYKTILNTDM
                     VEFGGNTKKENLRDYDVYFSSTPPSSKMPIASRTAIVLLDNGI"
     gene            17533..18183
                     /locus_tag="KRH23_001706"
     CDS             17533..18183
                     /locus_tag="KRH23_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HHS5224986.1"
                     /translation="MSFLGRKKEPDNTIQKILDISHKLFLEKGYEQTTIQDIVDNLDG
                     LSRGAIYHHFKSKDEIIKAITSRLYNDGFYGYDVKNDEGKTALEKLQYRLLHAYEQHN
                     KQDIFLMSSSLLRNPKYLATQFDEIINDIVPWIKALIEEGNQDNSMQVKNPEIAAQMF
                     GFLLNTWCIPTVYPGNPQQMIERFTLFGEQAAFMGISFMNDKIMCEYQKFVNKFSK"
     gene            18276..18959
                     /locus_tag="KRH23_001707"
     CDS             18276..18959
                     /locus_tag="KRH23_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5224987.1"
                     /translation="MQKEVAMNKLIKDCVNFFNDCGFSYSICGGYALELFANMHIRPH
                     SDIDIWISDTDKEKSIQYMLNQGWDIYEPLGNYLLRPIIDLNKQHIEQICVFAIKPDC
                     SFIELKKVEDDNYKMNIQCDEQLQFDFIELIYNPQKDGKFLFSQNQRIIRDMDKARLI
                     TSDNIPYMAPEVVLFCKSIYIDRLGYQKDFDVTVPLLSQEQRDWLVNALITAYPDGHA
                     WIDQLANQY"
     gene            complement(19136..19447)
                     /locus_tag="KRH23_001708"
     CDS             complement(19136..19447)
                     /locus_tag="KRH23_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HHS5224988.1"
                     /translation="MKIITEIVEFNVEENLSKEEFIEIVNDLELKFHSIQSGFIDTEL
                     LYDEKSQKWIMIQHWESIEDLKSASSKMFKDSSTEKFRKALKNQTVKMNIIPQIKSWK
                     L"
     gene            complement(19525..20343)
                     /locus_tag="KRH23_001709"
     CDS             complement(19525..20343)
                     /locus_tag="KRH23_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6597 domain-containing transcriptional
                     factor"
                     /protein_id="HHS5224989.1"
                     /translation="MLSVTRYSIKNVRLKPWVKFIWHFETKSNILLNNKLLPTDSIDI
                     ILNLSDVMEYKIENQDYTASNMHFNGIRDKHGFIIQHGNIRVIGISFYPFGLYLFLKI
                     PISEFNRQTVDLEAVSQLFAKKLEESLNPTQSVEKIVLYLEEVLLSILEEDLISNKYV
                     KLLNSFIYVNRYSNIKAFCDDTNINIKTLERICLKYTGYTPKILKRIYRFKMASNQLI
                     YNYKDDELFDFIYENEYYDQAHFIKEFKKFSGTSPIKFSGENKTIKENIKYSYL"
     gene            complement(20443..20967)
                     /locus_tag="KRH23_001710"
     CDS             complement(20443..20967)
                     /locus_tag="KRH23_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HHS5224990.1"
                     /translation="MEVTVKQKFTTKDMVETSLLIALVFIATKFINIRLPISINGGLV
                     HLGTAMLFISAIVFGGKKGALSGAIGMSLFDLISGWTLWAPFTFIVRGVMGYLLGKIA
                     WANGNNGNNFLINVIGICVSSIWMLFGYYVTEVILYGNFIVPLTSIPGNLMQVLIGLI
                     IALPISKVLKKCIK"
     gene            complement(20986..22128)
                     /locus_tag="KRH23_001711"
     CDS             complement(20986..22128)
                     /locus_tag="KRH23_001711"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal-phosphate-dependent aminotransferase
                     family protein"
                     /protein_id="HHS5224991.1"
                     /translation="MNKKINYAPGPTETRENVRLARAEKTTNPDIDIDFVEFYKKTCE
                     KFGNIIGTKNDVYILSGEGILGLEAACASLTEKGDRVLVIDNGIYGEGFKDFVTMYGG
                     EYVLFSSEYTKSIDIDELKAFLDEDSNFKYATVVHCDTPTGVLNDVSKICPLLKEYGI
                     LTVVDSVAGMVGERLSVDESKIDIILGGSQKAISAPAGLTIVGISQDAKNCIKNRKTD
                     VIGFYCNLNIWEGYYEKKYFPYTMPISDIMGLDKALDNILEEGIENVLNRHEKIAYSV
                     RKSIEEYGLELFLEEGYSNTVTAIKVPESIGALELTDYMLKNYNTLVATSLNQYMDTI
                     LRIGHMGENANLNKIEHVLNVLDKSLSALGFKGNGNLLNLFNKYYF"
     gene            complement(22408..24825)
                     /locus_tag="KRH23_001712"
     CDS             complement(22408..24825)
                     /locus_tag="KRH23_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHS5224992.1"
                     /translation="MAGCQRLVIKMINTTKIAKSNLKQNKSKSILIIITIILSTLMLS
                     SIGIYIVDAGAYQKENTIKYSGNYQGILANVDEKQADILSNHADVELTGEMNGVGVEK
                     LEDDSNISLAYMNEDALKLNSFEFIKGKLPSKENEIVLDSGALKALGYKNKDLGEKIK
                     ISYDDYKNDKKIEKEFIISGILKTSEISEAGKYYYAIISESYMRNTRDMSQEDFNIYV
                     KFNDKSNLSIEQAKEKLDKIANDIGLDTINTAVNENYINALKPDMETIMGGVFVGLVI
                     VLSSILVIYNIFYISIVTKVQEFGKLRAIGATKKQIKNIVFKEGFILAGIAIPIGIIL
                     GYVLANIIIKSFMDIDVKSSRLPVILSVVVISFISVVLSLLKPMKVASKVSIVDAVRY
                     TGNKISNKSKRKGYKNINLKRLSHANLERNKKRTYMTLASLILSGTIFITVSTALESF
                     DAEKMAREHFPYDIEVRLSGYEMNSDKNPKDNLNILQMDNPLSKDFFNQIKNMEGIKR
                     IESARSVKIGMEDYDVEFKYDLLQSINENDVKSLNKNIIDGKINLERLQTGDEIVITH
                     VDTAKEMGVKAGDKIRLTLYDGDKKIKKEFKVQAIAMGVPSFGIGKDFIDRTLKYDST
                     SSLGIYTEEGKYQEIKDSIKKIAKNNGFLETDFIDSRIESNKATISFIKIMGYTLTGI
                     IGVIGFMNLVNTMITSIVTRKKELGMLQAIGLTNKQLVKMLNSEAMYYTSGMMIGSIL
                     FGGILGYIAVIFLKKTGLSYATYSLPIVPILLMIVCILIAQFITTYLIGRSFNKESLI
                     DRVRYSE"
     gene            complement(24788..25471)
                     /locus_tag="KRH23_001713"
     CDS             complement(24788..25471)
                     /locus_tag="KRH23_001713"
                     /EC_number="7.6.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHS5224993.1"
                     /translation="MKILYTENLSKHYGKGESLVRALDNVDLEINEGEFVAIIGKSGS
                     GKSTLLHMIGGLDIPTSGKVYIDNKNIFTLKEEELAVFRRRKIGFIFQSYNLIPSLNV
                     WENVVLPIGLDGREVDESFIKELLKSLGLENKHDVLPNTLSGGQQQRVAIARALATRP
                     AIILADEPTGNLDSKTSDEVMSILKSMSKKYSQTLVMITHDDSIAQMADRVIFIEDGR
                     VSKVGDKND"
     gene            complement(25588..26898)
                     /locus_tag="KRH23_001714"
     CDS             complement(25588..26898)
                     /locus_tag="KRH23_001714"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HHS5224994.1"
                     /translation="MLKNMNLKDGLSVKDDYIMRRVIVYSVLSVLIVTLVFILFEYSR
                     LHKLYEHQIKNTQNIAGILIEKYPNDEIDIVNSIYNSDYSKVSTGEKAFKKFGYGLEN
                     KMSNDKNFSLYLKSFFKESFFIFLMMFIVVIGIIYYFIIYINKRLSKIYFIVDKMSQE
                     NYLKDTTESEETGYLVEYNEYFKEGIFSKINNCLYELNRSLKIKFIKLEKEKESVKSL
                     VTDISHQLKTPLASLKLYNTLLIEEELEEDEANEFLLTNKASINKLENLINSLVNISR
                     LEISMINIKKEDNDIKNTILNAVKSVTPKAKSKSITLNLNEFNSRIIPHDKKWTEESI
                     FNVLDNAVKYTQVNGEINISVEETANFFKIIIEDNGIGIEKNEFNNIFKRFYRGSADE
                     IESVEGSGVGLYLSRKILEEQGGNIIVSSKVGIGSKFSLFLTTM"
     gene            complement(26892..27599)
                     /locus_tag="KRH23_001715"
     CDS             complement(26892..27599)
                     /locus_tag="KRH23_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HHS5224995.1"
                     /translation="MNNILLLEDDKSLNRGISFKLKKEGYNVFSAFGIEEAKNIFAKE
                     EICLIISDIGLPDGSGFDFCEEIRKKSDVYIIMLTALDEEVDIVTGYDLGADDYITKP
                     FSLMVLISKVNALMKRVNTVKNYTLLVCDDLFFYYIENKLIIRTDDKEEEIILSKTET
                     KLLKYLMENSMQTLTKEQLLESLWDSSGNFVDDNTIAVNIRRLRQKVEKNPSEPKYIK
                     TVRGVGYMWGERSIKKC"
     gene            complement(27904..29745)
                     /locus_tag="KRH23_001716"
     CDS             complement(27904..29745)
                     /locus_tag="KRH23_001716"
                     /EC_number="3.1.-.-"
                     /EC_number="3.1.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0008253 - 5'-nucleotidase activity
                     [Evidence IEA];
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0009166 - nucleotide catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional metallophosphatase/5'-nucleotidase"
                     /protein_id="HHS5224996.1"
                     /translation="MKIRRYLILVIIILITTSQSFISYGLERFEEITIFHTNDIHGRY
                     AEGDDHIQIGNLATLKKETPNSILVDAGDCLHGLPIVNMDRGKSAIELIKCAGYDYIT
                     PGNHDFNYGKDRLFELSKSANLGENTLKFLSSNIFENGKKVFDSNDIKEIDGIKIGFF
                     GLSTQETKSKTGFKNVEGLEFKNPIESATEQVNELKGKGANVIVAICHIGTNSLSKPN
                     SIDIANEVQGIDLIIDGHSHTKFENGKQVGDTLIVSAGQYLENIGEIKLTLDTNDVEN
                     IKIENKSVRLIGKEEALKYKLDSAVSKKVDEIKEQQEKILDKVIGVTTNTLDGSYENV
                     RTKETNLGNLISDILLDKTKADISLFNGGNIRDTIEKGNITRRDIVDVFPFNNTIVTK
                     ELTGAQIKDVLEHGVKLYPEKSSAFLQVGGISYYFNPKQKEGEKITNIQKEGKPLDLN
                     KKYVVATNDYIASGGDEFPCFSKEPILKEFGNLESAVIEYIEYKKEISKNVDGRIGIK
                     SKDELISKNHESDLILSENEKNINDNEENLSNNIKSSDSDKNKSLDKTSSRESSNLGI
                     SKREAKEKSPKTGDLGFSNSIIIFIVSSTLICLLNFNQKKLKDKKSK"
     gene            complement(29958..30842)
                     /locus_tag="KRH23_001717"
     CDS             complement(29958..30842)
                     /locus_tag="KRH23_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4846 domain-containing protein"
                     /protein_id="HHS5224997.1"
                     /translation="MKVLKKITILSLITLTLVGCSNGEDKKVVEGSKKIQNSKKDEQP
                     IIVHKDANILKDRYEPPKGFKRVDVEKGSFESFLRNTKLKNYGEKVKYYDGRTKESKG
                     IYDSVFDVDIGNRDLHQCADAIMLMRAEYLYQNKLYDEISFDFVDGFKAKYSKWAQGY
                     RISVKDSGSSWYKATEYSTSYESFRKFMDIVFAYSGTLSLEKELEPVKVEDMKIGDVF
                     IVGGSPGHASIIMDMSENEKTGEKVFMIAQSYMPAQQTQLLINRKNPNLSPWYSLDFE
                     GDLTIPQWTFKRDQLKRF"
     gene            31050..31967
                     /locus_tag="KRH23_001718"
     CDS             31050..31967
                     /locus_tag="KRH23_001718"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016891 - RNA endonuclease activity,
                     producing 5'-phosphomonoesters [Evidence IEA];
                     GO_process: GO:0042780 - tRNA 3'-end processing [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HHS5224998.1"
                     /translation="MIDLTLLGCGGNVPMPNRFLSSVFINYKGRKILIDCGEGTQVSM
                     KLKKCGFKDIDLICITHLHGDHIFGLLGLLSTIGNSGRTSDLTIVGPVGIVDCIRSMR
                     NLVEYVPYTLKIIENPQGNFSLDNKVLRNLEISTISLEHSIECLGYSFNFRRNPKFDI
                     DKATKNEVPKILWNKLQEGQNIVLDSKQYTPDMVLGELRKGVKISLTTDTRPIESIPD
                     FIKDSDLFICEAMYGDDLDISKAVRNKHMTFREAANLAKLGNVKQLLLTHFSPSLDIP
                     SMYLENATNVFENTILGEDRLSLRLNFDE"
     gene            complement(32109..33443)
                     /locus_tag="KRH23_001719"
     CDS             complement(32109..33443)
                     /locus_tag="KRH23_001719"
                     /EC_number="1.8.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-disulfide reductase"
                     /protein_id="HHS5224999.1"
                     /translation="MRVIIIGGVAAGMSAAAKLKRIKPEYEVVVYEKTEIVSFGACGL
                     PYFVGGFFNDADELLARTPEKLREAGIDLNIFREVVEVDSESKKIKVKNIKTDEIYED
                     YYDKLMIATGARSIMPPIKNIKLKNVSTLKSLYDGEYLKKLLSNEDNKRVTIIGAGFI
                     GLEAVEACKKLGKDVDVIQLEDRILPQVFDKEMTDVLEEEINRHNVNLHLDEMVVELC
                     GEDKVEKVITNKGEIDTDVVIIATGVRPNTEFLSNTNIKMLKNGAIVVDEYGRTSVED
                     IYSAGDCATIKNIVSNENVYVPLATGANKLGRIVGENLAGREVSYQGSLSSSCIKIMD
                     MEAASTGITEKQAKDLGINVKSKFISDYNQTHYYPGRNKIYVKLIYDADTKVILGGQV
                     AGFKDAVQRANVLAAAIFGKMTTNQLGMLDLCYAPPFARTWDVLNVAGNVSK"
     gene            33784..35172
                     /locus_tag="KRH23_001720"
     CDS             33784..35172
                     /locus_tag="KRH23_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation:dicarboxylate symporter family
                     transporter"
                     /protein_id="HHS5225000.1"
                     /translation="MESSFLSQFLMITDFKTIFFIILLLGTFFIVRQFEKKKIKFSLR
                     TIYATVLGLILGIIIQAFAGFPNDTTQVTWLQEVSKWYSLFGSGFMDLLKMLVVPLVF
                     LSIIKVIINMKDNNLGTLTFKSLGMLLATTAIAAIVGIIVANIMKLGVGANMPTLVEN
                     QELKEINSLVDTLRGLLPSNPVMAMANGNIVATIIFATFIATSIKRLSKKHFETIKPF
                     IDFIEASYKIIVSVSMTVIKFMPYAVVALLANTITSQGISSIVSVLQFIVALYISVAI
                     LFIIHLIFITLNGLNPITYIKNSTEALLLAFTSRSSLGTLPVTIESLVQNHGVDEGVS
                     SFTASLGANMGMNGCAGIYPALMAVTLANMAGVNMDMSFYVMLLIVITISSFGIAGLP
                     GTATMAVSVVISGVGLGSYFPLVGGILAIDPILDMGRTMINVNGAMVSSITVGKSLGK
                     IDKEVFSKKNIS"
     gene            complement(35246..36454)
                     /locus_tag="KRH23_001721"
     CDS             complement(35246..36454)
                     /locus_tag="KRH23_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alginate O-acetyltransferase AlgX-related
                     protein"
                     /protein_id="HHS5225001.1"
                     /translation="MNRFFKVRLITAIMFLIILFAFSIFNVCYSGKDTIQEIKNSIAE
                     KSSLKDTISSIDNTVNDKVIYKNTFIETYGYLQKLMGKNEFSKFSVVKDTSGKMHYTY
                     FAKAPNPVGVIADRVRKFSDEMEKQNTKLVYLMTPDKYIKGVTEFPKGIPYSYSNETA
                     DNFLNQLKKYNVDYIDFRENILKSGIPKDDLFFKTDHHWKVETSFWAFGELVEQLNKK
                     YNMNLDENHYYRDKDNYNSIVYPKSFLGSMGRKTGILYGGIDDFTLIYPKFKTNYTYY
                     TDSKSQKFELKGRFEESLILSYPFNADLDLMDGQSDKYFTYLLGNRPLVKIKNIENPD
                     GLKVLFVKDSLIVPTAAFFSSVCSSIDMIDPRYYDGDILEYAKSHDYDFVFISVYPQN
                     LTKEFFPFCE"
     gene            complement(36469..37887)
                     /locus_tag="KRH23_001722"
     CDS             complement(36469..37887)
                     /locus_tag="KRH23_001722"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008374 - O-acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBOAT family O-acyltransferase"
                     /protein_id="HHS5225002.1"
                     /translation="MLFSSLIFLFYFLPITLVLYYVFRFNRTIQNMILLAVSLFFYAW
                     GEPKFVVIMIVSIIMNYIFGLLVDRYRESKIKVKVFLVLMCAYNIGVLFIFKYLAFAL
                     RNISELISTELTIPSIVLPIGISFFTFQGMSYVIDVYRRHGEVQKNPFYVGLYIAFFP
                     QLIAGPIVRYESVAEQILNRKETWNKFSIGTCRFITGLGKKVLISNNMAIVADYIYTM
                     NSQGEIAASLAWLGSIAYTLQIFFDFSAYSDMAIGLGLMFGFKFEENFNYPYISKSIS
                     EFWRRWHISLGMWFKSYIYFPLGGSRVANKDIMIRNMFIVWLFTGIWHGAEWTFVIWG
                     ILNFVFLIIERFIMFEKIENHNFIKHIYALLVVNFGWVLFRSPNLKEAYNYFKAMFGG
                     NGAIWSDYTYMFLKEYWVFFIFAFIFSVPIAKKINKFVVEQAKYSMIFNVFYPISAIL
                     LFFISVTYLVTGSYNPFIYFNF"
     gene            complement(37905..38981)
                     /locus_tag="KRH23_001723"
     CDS             complement(37905..38981)
                     /locus_tag="KRH23_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5225003.1"
                     /translation="MKTLKVFFCSTKYLILVFIFFINTTFISSATSDKILDLSFKKIE
                     TDLNSKITYEDTGVKIETDSSKSDKERYLYIYQNIKENWSMYNNFYIEIQNKNKSSQR
                     INLSIQSKNMLEFRLKEGSEVFLEGKNIIYSDKIKEGCIEVPGEFEGKIYVNFNSLIN
                     EESNVVLDSNMLSNIVSWGITFIPSDEEHNIVIIKKISLLSEEKLRFLNNIKIIGDEE
                     VQIPVLGQSISQYEVLGLKSDSKIKYSLMGKQDNVSISQKGKLTLSNKAKPGQIILQV
                     NVDDKFKIGKKITLTESWSVNKKDKDGVPYTLVYPEQSPTVQDMKKINFMNNIITFVR
                     ILFVSLVIICFGIYLYWKKCSKTK"
     gene            complement(38992..41298)
                     /locus_tag="KRH23_001724"
     CDS             complement(38992..41298)
                     /locus_tag="KRH23_001724"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HHS5225004.1"
                     /translation="MKKNSKKILITLTIITNVIYILWRIFYTVPKEEGKFALICAIIL
                     LFVETMGMMEMFVHYYGMSNIEYPEKPIISEELYPHVDVFIATYNESVDLVRKTVNGC
                     IHMQYPDKKKVHIYICDDGNRKEMRILAEKMGVNYITRTEREGAKAGNLNNAMQHTNS
                     PLIATFDADMIPMHDFLIATVPYFLKNEQAKKDGEKEEYEKVGFVQTPQSFYNPDLFQ
                     FNLHSEGRIPNEQDYFYRDIQLARNRTNSVIYGGSNTVISREALEEVDGFYTYSITED
                     FATGILIQSKGYRCYAIPEVHASGLSPTDLKSLIKQRERWARGCIQTGRRLNILFRRG
                     LGFWQKISYISSITYWYASIKRFVYIMAPILFSVFNVIVVKCTLLQVLVFWLPMYILS
                     SLSLKIFSQNIRNTRWTNIYETIMFQSLMPAVILETFAISKNKFSVTNKSKLEENRMY
                     KFLQGIPYFIYMVLSIIGILKMFVAIFKMSSMTYSVVLFWLIGNLFNLVMATLFISGR
                     QQLRKSERYIAEIDFKLKQNSYVLSSKTIDISENGFAFLLENPEYISPEEEFEVEFRE
                     KSGNEMYIANMKAKIVNVVEVNSKWKYAAYITHIEDSEIDNWMCIVHDRIPTLPMTIS
                     NQLGFFDDLQINVKKRIEKTRTLSRRSPRINMNFQMDIKNTGKLRIVNFNYQYVLLNF
                     ENKSIYPKEIALEINENIVLECDLCEGKIDERGILYKVNNIDSIMQNFFLRDEMMDWI
                     LQNKTILVSKPSEKKEKSIDEFEPMEYI"
     gene            complement(41303..42283)
                     /locus_tag="KRH23_001725"
     CDS             complement(41303..42283)
                     /locus_tag="KRH23_001725"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0000272 - polysaccharide catabolic process
                     [Evidence IEA];
                     GO_process: GO:0071704 - obsolete organic substance
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 5 protein"
                     /protein_id="HHS5225005.1"
                     /translation="MFFLSIAFIGFYLVIRDNSDTVKMQRGINIGNALESPKDFPWDV
                     KMSNKFFDDIKDAGFDTVRIPVRFSDYTSDSDNFKIDEEFFKKIDKYVDYALDKELIV
                     VLDLHHFEEIMKEPRVHKEKFLKIWQQIANRYQKYDKKLVFELLNEPKENLSSQLLNE
                     YIEEAIKIIRKTNPKRTIIVGPYNFYQIDYLNELNIPKDSNIVVSFHYYEPNDFAFQG
                     NIYHKGFEHLSNITWEGTNEQMDYLKKRFDTVENWANKNKVKIFLGEFGITKEAPETS
                     RRAWVKAVREEAEKRNFSWAYWELASGFGIYNQIEGTWDRDILSALIEKR"
     gene            complement(42587..44335)
                     /locus_tag="KRH23_001726"
     CDS             complement(42587..44335)
                     /locus_tag="KRH23_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4091 domain-containing protein"
                     /protein_id="HHS5225006.1"
                     /translation="MEISYVLKDCTFKHNKYSVVEAETWKDKDLDIVVAKGEKFAFQI
                     MLKATEEFNCTIDKSSAISWKGLGNRVRLALNMPNSLENNFSINILGYVQDDTKAFVN
                     DAILRDKDVLVEQYLPQTFWIEGQVPEDFEENNLDIGIDIFKSFGYEDEEKVCTIDVP
                     VKVRNVVLKPLDESKFFLDLWQHPSCLARMYKVELWSDIHFEIVDNYLKELASLGEKV
                     ATVIVSDYPWAGQSCYKVYKNPSNLYEYNMVSVSKGLDGKIKCNFESMDRYISIADKY
                     KMAKEIDLFGLLGNWCAGEFGNPVEGYKDPIRVRYFDEKDKVFKFINNTNDLKEYIGL
                     VLNHLIECGLWDRVRIIADEPNNPEVVKECIEFINSTVDTHQVKYKSATHDQNFLDRA
                     KDEIDDMSINLKLTIQNYKDIESLKKKINDKGGILTWFVCCFPEKPNSFLSSPFVENR
                     IIGWYTYYFGLDGFLRWDYNLWTEDPWKDSSYKFPIWKAGDMFFVYPGKDLKPVRSVR
                     MENLRFGIQDFELFTMLEKEKGREYIEVELMQELLNKKENAEIKGFGDIELGYSLDNW
                     GYDKVKKYVLELLDRV"
     gene            complement(44393..45202)
                     /locus_tag="KRH23_001727"
     CDS             complement(44393..45202)
                     /locus_tag="KRH23_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HHS5225007.1"
                     /translation="MKTARRLLSDGLLLFIACASLVPFIYMLIISLKITYNSYSLDIS
                     FSTVTLQNYIDIFTKKGFAQYFFNTAIVSFSGVLLNLVFSTLAGYSFAKMDFKGSDKL
                     FLFMIMTLIIPSQVTMIPLYIIMKHLGWINSYLALIMPIPTAFGVFIMRQAILGVPKE
                     LLESAKIDGCSDFRILIQIVLPLIKPALITLAIFTFMGAWNEFMWPLIATTKDAMRTL
                     TVGLSTLKTFQITNYGQMMAGATITFLPPFIFYLILQSKFVEGVSLSGIKG"
     gene            complement(45218..46135)
                     /locus_tag="KRH23_001728"
     CDS             complement(45218..46135)
                     /locus_tag="KRH23_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HHS5225008.1"
                     /translation="MENLVREFEENSKRKKTKLNIKPYMYILPLGIILVAFYVIPIIM
                     SIYFSFTKYNIISPATFIGLENYKKLFTDETLKVSIINTIKFTVVVVPCQTILSLILA
                     VWITGKGNSKIASFAKGAIFIPVLSSMVLIGMVWRALLNGEGSIIYQVLGAFGIESSK
                     LLGDSKTALPTLMFISMWKNIGYFMVIYISAIMNLPKHCYEVAKVDGATKLQEFIKIT
                     VPLLKPTTIMVVFLGSIWSLQVFDLIYTVTGGGPGISTMSIVMHAFNLNFKNFNSGYA
                     MTVANVLFLLIAVVSILQNKLVRRDNSDF"
     gene            complement(46233..47543)
                     /locus_tag="KRH23_001729"
     CDS             complement(46233..47543)
                     /locus_tag="KRH23_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HHS5225009.1"
                     /translation="MKKENKMEGIKVGMLKKLCSLAMVAIMTTTLITGCSSGNGKDSK
                     KDGEKEKLVLWMPPVENNMKEVWDPILDKFEEKNNCEVDLQIIPWDNYSEKFATAISA
                     GEGPDVGYMYAEMYPQFIESGAVEDLTNYATKEDKEQSIYIKTSEMMGGMYGMPFQAA
                     NPGVLYYNKDILEKLGEKPPKTWEDFKRICKKATQDTDGDGKIDQWGLAQGWGAKTFG
                     NLNWNWYPYLWQAGGDIFNDDLKSVKFNDKSGLEAAKFLKELQAYVPEDSLSKDSNEM
                     IESVFGPGKAAFTIMLSSAATSVFDESFPDLNWGFVTGLEDKKAATFGAVDHLSLMSS
                     AKNKELAYKLIQHMLSVESMTEFHKAIPRAPITKGEPYQGDERFKEMVENDKNVYRPL
                     VVGPHGVEIYEYLWKELQTMISGDKTPKQALDDAAKYSNDLLAQ"
     gene            complement(47866..48606)
                     /locus_tag="KRH23_001730"
     CDS             complement(47866..48606)
                     /locus_tag="KRH23_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HHS5225010.1"
                     /translation="MKFKYIDEIRRLIDIIENEEKVNMEKAVQIFVEAIESKNAIFSF
                     GASHAGILTEELFYRAGGCVLINPVFAKSLMLDTAPITHTSKMERLEGYGTALADKTP
                     IKKGDVVIVHSVSGRNPVSIEFAMKAKENKAIVICITNLSYSKSVSSRHSSGKKLYEV
                     CDLVIDNHGQKGDACVEIDGLNQKVSPTSTVIATTVMNSIIAQATQELVNKGLKNPPI
                     FYSANIDGGDELNKKIFDEYKSVIHYEY"
     gene            complement(48609..49868)
                     /locus_tag="KRH23_001731"
     CDS             complement(48609..49868)
                     /locus_tag="KRH23_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HHS5225011.1"
                     /translation="MLDFISNNILRNPSMLIGLIAAFGLVLQKKKASDVIKGSLLAAF
                     GIIIMETGTGMLVSSIAPINGAFQSISGGAVTKGLSDVTFTASYGGIIGLAMFAGLAI
                     HLMIARFTPIKTIFLTGHMLYWFPFIFVASGVEAGLNGGVLIAFAAVLSALYWSIMPW
                     LLRKYVFDVIGDDSFTLGHPSGCLALISGFVAKLVGNKEKSTEDINIPQSLSFFREIS
                     ISGGMAVFLMFIVVGIVIPGAFKDSNEFIGTYAIKQGLSFGAGLIIMLYGVRMLINQI
                     MPAFQGISEKVVPNALPAFDCPILFNYKPNAVLIGFLVAMLTSTAMILICNYFNVFNL
                     LLIPLVITSFFECGAAAVIGESQGGIRGAIIGTAIAAIFMVVLVGISAVIYSGTIQNW
                     ILIFGGNDLSLFGIISKFIGSLFGGIL"
     gene            complement(50001..50288)
                     /locus_tag="KRH23_001732"
     CDS             complement(50001..50288)
                     /locus_tag="KRH23_001732"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HHS5225012.1"
                     /translation="MKILAVCGFGVGSSMVLKMTIQKALKQLGIECEVENTDINSARG
                     ADCDCIFTSQELLNELKGTCNVDVYPVKKYMDLAEVTEVVQTFLSDKNDKK"
     gene            complement(50301..52220)
                     /locus_tag="KRH23_001733"
     CDS             complement(50301..52220)
                     /locus_tag="KRH23_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HHS5225013.1"
                     /translation="MKERAKKILDFIIKNNNVTSQELQEKFNVSKRTIYYDILAINKQ
                     LGKSGNIKNVKHKFIFEGNLCDARKIISTEEDKFLDSDYRKTFILNKILLGEKISIEK
                     LTNEMLLSKNTVVQTITDVKKYLQTMGLRLEYKGKYKIIGDEYVIRELFLIIVQENVL
                     EINSISEEVSSFDTKGHIKLTDYSLLNLTKFVEFLNKRIRDGKTLYSYKYLNEAKKIS
                     YFSNCKELLCEEANENEQAYICTYISSLPSLNSEVKEDVVEEYVDKLIDKFEVNTAIK
                     LESKHEFKKNILRHLHSSYNRIRFKFPIRNPMLDETKYKHESLYKIIKSIIENEEEFP
                     VFEGIREEEIGFIAAYFGGYLRGSRDNGLRRNKVLLVCPNGLMVSKSLEIQLYKYIPT
                     IEIVGIVSIKQLKEVNVYYDYIITTIDIQNVNNVIVVNPLLTSSDVQLLMNKLISVKE
                     NEKYFNLELIIQAIRKNGVINNEEALKADLLNIIHKIDEGEMYQPMLKELINAERVNI
                     IKSVRDWKEAIKIASKPLLEDNSIEELYIENMIKSVEKYGPYIVLADRFALPHASSKE
                     GVNKLAMSLLIVEDEVDLLGKPVNIFMVLAAVDNTTHIRALASLSEMMYEEENVKLII
                     NGDKSSIIELINKQN"
     gene            complement(52564..53088)
                     /locus_tag="KRH23_001734"
     CDS             complement(52564..53088)
                     /locus_tag="KRH23_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5225014.1"
                     /translation="MKIDLEMIELFEQLEEIFRSASTIPFSHKCTVDKDEVLAIINDI
                     RTLIPEEVTQAVWINKERNKIISQAKQDATNIVEQAKKEAERIQQEYQDNIEELKKNS
                     EDVVKAYVESSEPVVQADQRAKDIVDRAERIANEIRIGSIEYAEDVLSSVEYNLREIL
                     EEVKRDKAELRPKK"
     gene            complement(53092..53589)
                     /gene="coaD"
                     /locus_tag="KRH23_001735"
     CDS             complement(53092..53589)
                     /gene="coaD"
                     /locus_tag="KRH23_001735"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004595 - pantetheine-phosphate
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HHS5225015.1"
                     /translation="MENKPRKAIFAGSFDPITNGHLDIICRASKLFDELQIGVLNNPN
                     KKGLFSFDERVKLIEKSTSHLNNIKVVTFDGLLINYCQENGIGALVRGVRSGADVDYE
                     LQMAHMNRELNPDIETIILPSCTKYSFISSSLIKEVLLFDADIKNLVPKIVLEELKKK
                     TSGGN"
     gene            complement(53591..54145)
                     /gene="rsmD"
                     /locus_tag="KRH23_001736"
     CDS             complement(53591..54145)
                     /gene="rsmD"
                     /locus_tag="KRH23_001736"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052913 - 16S rRNA
                     (guanine(966)-N(2))-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0031167 - rRNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HHS5225016.1"
                     /translation="MRVISGKARGLKLNTPKNEDVRPTTDRVKESLFNMINSYIMESE
                     VLDLFAGTGSLGIECLSRGAKSCTFVDISKESIDIVKSNIKKARVESESIILNLDFKT
                     AIDKLKLQNSKFDIIFMDPPYYKNMFIEAIEKIDNSNLLNEDGIIVVEHDTNDLFPDK
                     ICKLEKTRDKKYGNTTLTFYKMEA"
     gene            complement(54204..56261)
                     /gene="recG"
                     /locus_tag="KRH23_001737"
     CDS             complement(54204..56261)
                     /gene="recG"
                     /locus_tag="KRH23_001737"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HHS5225017.1"
                     /translation="MDLYKDVQYVKGIGPKKADKLNKLGIFTLKDLLYYFPRQFEDRN
                     NLKKIAQLEDGEKVTIKAVISSINTFSPKEGMTLTKIDVKDETGSAKLVFFNKSYIKN
                     TFRPGDSILVFGKVKKKFNNLELTSCELEYLTNSPKNTCRFMPVYQLTYGVTNKEIMS
                     IIRTVLEDKELIIQEYMPQRIIEKYRLCSIDFAVRNIHSPSSKESLKIALYRIVFEEL
                     LILQLGLFVFKSGRNKEDGIKFETSKDLKKIISALPFKLTKAQNRALDEIIQDMNLEK
                     IMNRLVQGDVGSGKTVVALLALANCVLNGYQGALMAPTEILAGQHYISLTESLKDFGI
                     NVGLLIGSLTKKQKDTVLEQIKNNEIDILIGTHALIEDKVEFNNIGLVITDEQHRFGV
                     MQRSKLSLKGANPDILVMTATPIPRTLALILYGDLDISIIDELPPGRQPIETIAIEKS
                     KRDRAYNNLVRREVESGRQVYIVCPLVEESEAIEAKSAVELVEELRAEYFHDLRLGLL
                     HGKMKSSEKDEVMRLFKNKEIDILVSTTVIEVGVNVPNATLMIIENAERFGLAQLHQL
                     RGRVGRGSHKSYCVLIYDSKTDVCRQRMAIMEETNDGFKISEKDLEIRGPGEFFGTRQ
                     HGLPELKVANLFKHIKILKLAQQEARYILGEDNNLQLKENMALKKEIIDKFKDTLKEI
                     SLN"
     gene            complement(56342..57985)
                     /locus_tag="KRH23_001738"
     CDS             complement(56342..57985)
                     /locus_tag="KRH23_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HHS5225018.1"
                     /translation="MIQYIDGKRLREMFISGANNLQNNKELVDKLNVFPVPDGDTGTN
                     MSLTISYALKELAKVENDNISDIGKALSKGSLMGARGNSGVILSQIIRGIAKSIEGKS
                     KLSTEDLAKAFKNGSDTAYKAVIKPIEGTILTVVRESGEFAIKTAKKEKDVVKFLSML
                     VKESNSSLERTPDLLKNLKEAGVVDSGGKGLVLIYEGMLASIKGDNIEIKNVDLDTNI
                     STSMDFAKSTTSTDDIKYCYCTEFILESSKVEDTKIRDIMMAYGDSLAVVGDDGVIKV
                     HVHTNDPGNVLQEALKYGQLLTIKIENMKLQHENTLLDVEEKKENDSEPLEEEKEFGF
                     IATSMGEGLANIFKDFGVDHIIEGGQTMNPSTEDFMNAIKHINAKNIFIFPNNSNIIM
                     AANQAKELSDKNIIVIPTKNTPQGFAALVTFNGELSEDENKEAMMNALNSVKSGQVTF
                     AVRDTVMNEIDVKEGNIIGIAEGNLLSAGDYVDEVTSNLIEKLVDEDTAIITLFFGED
                     VTESQANELRTSLEEKFEDVDVELYYGGQPLYYYLISVE"
     gene            complement(58004..58354)
                     /locus_tag="KRH23_001739"
     CDS             complement(58004..58354)
                     /locus_tag="KRH23_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HHS5225019.1"
                     /translation="MSAKVTNQYGNIEIDNQVIAQVVYRAAMESYGLVGLAYKSKGIV
                     ELLKGENATKGVRVEEVEEDAIAIELYVIIQYGTNISTVANNIIDRVKYVVEKMTGVR
                     VTRIDINVQGIRVK"
BASE COUNT        19429 a         9894 c         6645 g        22576 t
ORIGIN      
        1 agttattatt ttaatttcat actttacttt ttctataaac ctattataat taaagtataa
       61 tcatttttgc aacttgttta ttttattata aaaatgtgaa acttattaca taaggaggaa
      121 tttaacatga aaaatcatac ttataaagaa atcaaaaaca tatatggaaa aataagccct
      181 tttgaattta aggacaaatt aatagatatt gcaaaataca ctgcaaaaga aaataacaga
      241 gaattacttg atgcaggtcg tggaaatcca aactggactt gttcaactgc tagagaagcc
      301 ttttttactt ttggtcattt cgctattact gaaactcgtt ctaattggga tttaggtcat
      361 ttggctggaa tgcctcaaaa aaagggtatt aaagaaagat tttttaaatt tataaatgaa
      421 aatatagata tgcctggagc atatttagct agagatatta taaactttgg tataaatgaa
      481 cttggatttg atggagatga atttgttcat gaactagctg atggaattat tggtgataac
      541 tatccacttc cagatagaat gttacctcat atggaaaaaa tagtacacga ttacctagtt
      601 caggaaatga aatatgatat atcaggtaaa tatggtgatg tagaaatttt tgctgttgaa
      661 ggtgctacag ctgctatgtg ctatatattt gattcattaa tggcaaatga acttctaaaa
      721 aaaggagata caatagcctt aatgactcca atatttacac cttatcttga aatacctaac
      781 cttcctcgtt acgactttaa agtggtaaat ataaatgcta atgaagttga tgaaaaaggt
      841 gctcacacat ggcaatatac aaaaaaagaa ttagagaaac ttcgtgacaa atctattaaa
      901 gctttattcg ttgttaatcc gaataatcct gcttctatag ctatggatga aacatcttgt
      961 aataatctaa tagatgtaat tgaaaattat aataaagatt taatgataat atcagatgat
     1021 gtatatggaa cttttgtaga agatttttca tccttaatgt caaaactacc ttacaacact
     1081 gttggagtat attcttattc aaaatatttt ggagttacag gatggagact tggtacattt
     1141 gcccttcata agaaaaatgt ttttgataag aaaataaatg atttaactgg agaattaaaa
     1201 aaatcagtag ataagcgtta cagtgatatg agtcttaacc cttctagcct ttcatttatg
     1261 gaaagagttg ttgctgatag cagacttgtt gctctcaacc atactgctgg tctttctact
     1321 ccacagcaag tacaaatggc gtttttctct gcttttgcat tgattgacaa agtagatgcc
     1381 tacaaaaaac tcaatatgag tatctgccat agacgtcaaa aactattatt tgaagcttta
     1441 gagcttccaa ttaatgaaaa caaaaacaat gctgcatatt acactcaatt tgatattgaa
     1501 gaatgggcta aattaaacta cggagaagac ttatttaaat ttataagtaa aactgcatct
     1561 ccagtagatg ttctttataa attagctaat gactattcag tagttttact tagtggaaat
     1621 ggattctatg gtcctgaatg gtcaattaga atatctctag caaatctata tgatgaagct
     1681 tatactaaga taggaaaagc cataagagag atattaaatg gttatatcgt tgaatggcaa
     1741 aaaattaaga aataattata ttacactgaa atatctaaat tatatgaata aaagagttta
     1801 tgtagacctt aactactttt tttgatataa tcctatcgga attataaatt ttatttatga
     1861 aaggcagaga atagtatgag tattaagaaa aaagttgcca tagtttttac tggtggaact
     1921 atatctatga cagtagatga taaagtcgga gcagctatac caactttatc aggtgaacaa
     1981 atactatcaa tggttaccaa cattgataaa gttgcagatg ttgaagtttt taattttgat
     2041 gaaattccag gacctcacat aacaccttat agaatgatgg aattgaaaaa ttatgtaaat
     2101 gatttattag caagaaaaga tattacaggt gttgtaataa cacatggtac agatagttta
     2161 gaggaaacag cttattttct agaccttaca attgacaaca tcaaacctgt aatagtcaca
     2221 ggtgctatga gaagtagttc tgaacttgga tatgatggtt caagtaattt atctgcatca
     2281 gtttgtactg cagtatccaa agatgctatg ggaaaaggag tccttgtagt tttaaacaat
     2341 gaagtattat tagcttctga agctactaaa acaaatactc tttctctaaa tacatttaaa
     2401 tctctaacta gtggcccatt aggaataatt gactgcaacg aacttgtcct tacaagagat
     2461 attgtaaata gaacaattat agatactgat aaggtagaat ctaaagttgc cttatttaaa
     2521 gcatatgtag gagaaaatgc tgactttata agatttgctg ttgatagtgg ttataaaggt
     2581 atagttattg aggcaatggg tagaggtaat attcctcctc aaatgctttc tggagttgaa
     2641 tatgctagag aaaaaggact tcctgtagtt atagtttcta gatgtcattc aggtagagta
     2701 ttcgatagtt atggttactt tggttctggt agagatttaa aaaatcttgg ttgtatattt
     2761 ggtggggact taccaggtca aaaagctaga ataaaactta tcttagcact tggaaaaact
     2821 gataaccttg atgaaatcaa agatttcttt gaaaaaggaa tctattgcta attctaataa
     2881 cttctattta attatttatt gatatttcaa catttttaaa tcaaaatcta atacttatgt
     2941 cagttaaatg tcagcaaaat attttatcca caagttttcc acaacttatc cccaatatta
     3001 tccacaagaa aaaaggtagc acttatatta gtagctacct tttatttatt aatcttcatc
     3061 tttccagctt tttatccaat ttcctatttc tattattttt tcttcagtta tttcttctcc
     3121 atcatgcaat tttgaaatta gttctgataa tggattgtta tgtagacctc caaaaattct
     3181 ttttccctct attttgagat attctttctc ttttattaat actctatagt gtacatgttt
     3241 cccaattctc tgcgatatga aaaaaccttt tttagttaat ctagctaaaa gtgtaattat
     3301 agttgtatgc ttccaagcat atgttttttc tatttcatct gcaacatctt ttgatattac
     3361 agttttataa ccagtattcc atatgtattt cataattttt aattctgcat ctggtaattt
     3421 tttattcaac ataatatatt ccttctttca atttatgtca cttcctcaaa cttatctagc
     3481 ttaaattaat aataggagct ttttatcaca aaaactacag gtaaattttt ctatatattc
     3541 tacgtattta gtctgttttt taagtgtgaa attacgttca tacctataaa tttattcaat
     3601 tttcaaacaa tcttgttgaa taataactaa ttctattgta ttatttagtt atagaataaa
     3661 actaaatcgg caaaactaga gaaatctagt gacgcaaagc tatagggact aagacttata
     3721 taaatatctt atgagttatg tcagccagtt gccaaagaga tattgttctt tttgttttta
     3781 tgaaagtttt ttaatgggat aataatttat atgtttagag ataaaatgga taaatgtaca
     3841 catatattga ctgcttatat tagcagttcg tatgattatt gtaatttttt ggatacaatt
     3901 tacattccat atagttaata taaaacttgt gtttattgtg atagtgccga acaggtgtta
     3961 atacgattta cattccatat agttaatata aaacatgaac ctaaattaaa tggtgataga
     4021 ggggaaataa tatttacatt ccatatagtt aatataaaac atcagttttt tagtctatta
     4081 tattataact tttgaaattt acattccaca tagttaatat aaaaccagag atagaaatta
     4141 tttttattat acgttttttt atgtttacat tccacatagt taatataaaa cagataacat
     4201 acgtgattat gatattgctt tttcgtatgt ttacattcca catagttaat ataaaactat
     4261 ttgaagctaa cagtaagaag tctcagataa taagtttaca ttccacatag ttaatataaa
     4321 accttatgcc ctaatgtagt tttattacat tgtaaaattt gtttacattc cacatagtta
     4381 atataaaacg tgactattat tattaatata gaatttgaga ctaaagttta cattccacat
     4441 agttaatata aaaccccaaa ataaattgag tatttccaat gcctacacat atacaaatct
     4501 ctcaaatttg cagtgaacca tgagtagtgc aattgataac acttatcaca agtcctcaat
     4561 gccttatatt tcaactgtta agccttaatt tcttcaaaaa atcgaacact gcaaaatttc
     4621 tatgacttta ttatatcata aaaatattat ttttgaatat ctgtaccaat ttgtgatata
     4681 ataaaagcaa gaataactac aatctatttt gctgtagagt ggagttcata atttagaaat
     4741 tacttagttt tatggaatct gatttttaaa tcaaattccc aaccactctt agttgccgct
     4801 ttgagtggtt ttttacgctt tctaaatagt ttgctagcta tataaactat taagctagca
     4861 gatagacttg ctagtatgcc ttgtaaaaaa ttatccatgt atattcacct cccttcttaa
     4921 cgtcgggagg ataatttttt gatacatgaa ctccactcta taaattgtag attacatctt
     4981 cttgctaaaa atattataac atataattct tacatatttt acctatttat tactttttac
     5041 attataataa tattctttta atcaaaaaaa cacctactat taaagtaaat gtttttaagt
     5101 atttttaatt ttaaaattca tatagttcat atgaaactaa atataataac tcaacatatg
     5161 agcaatatcg agacatttac ataccacata gttaatataa aacgaaaata aaaaaattaa
     5221 acttataaaa cccttattaa tttacatacc cactagttat ttatattcaa aaaaatcttc
     5281 tccatctggg ttataaaata atattctact tgccaatcct tgttcatatt tataattttc
     5341 tttatcacct acataagaaa atgttaatgt catgcttctt gatggatcta atgaaattat
     5401 atctaaataa atagtacatt tttctcctgg ctttaataca ccaaaactat taaaatccat
     5461 ttttatttta gcgtattgcc ccatatataa tgttgaatta gcttctccat aaacttttaa
     5521 ttttgttaca tctaaatttt gtgtacttgt attttctata tttataggaa ctgttgggtc
     5581 tttatatttt tcagtataat attcaaggtt atcatcataa cattcaagat aacttccttt
     5641 atcttgccaa attatgtgat ttgaatcaaa atcaatcttt aatccacata ttatattttt
     5701 atttgaagat ggaagactaa tattattgat ggtattttca cactctagca taattttatc
     5761 acttagattt cctatcccgg ttacttttgc agcattttta agtatatctt tattacttcc
     5821 aatatcaact agtacaatag gattattttt agccattggt gaaccaacta aagcataaac
     5881 taaatcagta ccactagcta tataaaattc ttttgcgcca ttatagaatt tatttactat
     5941 ttttttatta gtatcatatc tatctactcc acccaatcga gttgaattag tatcatttac
     6001 taaactatca ctcattgatg aagtgccacc tattgcataa ctttctattc cagtagtatt
     6061 aaatggcaca cttttcccat cagttaatat tataggtgct ttgtctctaa cagccacaga
     6121 ggcaatactc atagcatctg gttcaccttt gaaagcatta gttaatatta ccttatttgc
     6181 tttattaata gaatttattt cttttgctac attataactt gtcttaatcc tatcattacc
     6241 ttgaagcctt ctaatctcta ttcctttatc ttttagaaaa gtttctgttg ctttatcaat
     6301 ggaactttct cctcctatta tgtatacctt tttagctttt tctactcttt taagagttgc
     6361 attaggtata ttatttttct tagttaaaag aattggtgca tttgttgctc ctgcaagtcc
     6421 actcgcactt agcccatcag ccattgtact atctgcattt ataagtattg cagtagtata
     6481 actttgtttg tcagctatga taccagcagt ttcatattta tctgctcctt gaattttatc
     6541 aattttatca agtgcattag ctgatatagg aaaaccaaca acaaacattg acactaaccc
     6601 tagtgataat aatttcttta atttcacaat atctccccct tttatatatg aaatactata
     6661 tatcttaata attctacatt aaattttctt ttcctccttt aacgatattt atcttcctgt
     6721 taatttaagt gtatacaaat acgtgttata atgtaactgt aaagaattaa aaagataatg
     6781 acataattag agcagtccaa ctgttctttt ataaaactaa cttataaagg gaatgtacat
     6841 atgaatatca aatcagcttt tataagaaaa agaggggaaa aattctatgt atatgtggag
     6901 tacatagagg aaacaactgg caagataaaa cagaaaagtt atggaagtta tgaaaagaaa
     6961 aaggatgctg aaaaacattt aattgaaata aaatctacta taaacaataa taagtttgtt
     7021 gctccaaaag atatgacatt tgtagaaaga tgttataaat acatagacat gaataaaaat
     7081 aattggtctc catatactgt tacaaataca aaatcttggg ttaaaaatta catagaacct
     7141 ttttttaaga atctaaaact cacagaagta aatcctagtt cagtacaagc ttttgtaaat
     7201 tataacttta ataattctac ctttactagt gctaaagtaa ggtatagctt tctaagttct
     7261 gtaataaggg aagcatatag attaagagaa atacaagaaa attcatgtga ttttataaaa
     7321 cttccttcta aagaaaaata ttctacaaat gaaatataca atagagaaga agtattattg
     7381 ctaatagaaa agttacttgg taataatata gaaataccta ttcttttaat gttacttcta
     7441 ggtttaagaa tgggagaagc tactgggctt aggtggtcag atgttgactt agataacaat
     7501 ctgataaatg ttaatcaaat tcttgtctat tctaatggca aaatatcttt taaagagcca
     7561 aaaacaccaa aatcaaaaag agctttatca gctccaaaag aattaattga aaaattgaaa
     7621 atagaaaaac taagacaaag caaattaaaa ttgcaaggta tcctggaaaa caaaaataac
     7681 ttagtttgtc taaacaccaa tttaaatccg tttctacctt cttcactaag aaaaacgttt
     7741 cataatttta caaaaaaaaa taatctaaaa aaaattagaa tacatgattt aagacataca
     7801 agtgctactc tgctgctttt gggaggtact aatatgaaag ttgtttctga aagattgggt
     7861 catacagata taaaaataac tatgaataga tattctcatg tacttaaaga aatggacaaa
     7921 gaagcttccg acaatctaag cgaacttcta tttaaatagt aaaaactgac tgtcggttaa
     7981 atgtcagtta aacgtaaaaa ataggttttg tcagttgatt gtcagtcaat tattttataa
     8041 taatttcact taaaaacgtc tatatctaca cattttacta tttatttatg cttactaata
     8101 tctatctgtt attactaatt ctaatagctt ctatttaatt atttagttca gtttacaaga
     8161 aaatacatac aaaccataaa atgagatgtt gacaacataa cagacagtat gctcctgtaa
     8221 aaggtaacat actatctgtt atattgtctg gattcccaaa ttagctattt ggaacttaac
     8281 taaaaaatcc taatataagg gcaactatta taatggcaat cggaatacat actgtgtaat
     8341 cctgttccat agagtcatca tctgaatgta gttttacaat tcgcaattta gcaatcagtt
     8401 tgaagcagaa atagcctatt attgttccaa ttacattcgt gagtaagtcg tctatatcgg
     8461 ttgctctgtg taacgtaaaa agctgaatag tttcgataaa aagagataat ccaaaaccaa
     8521 tcaagaatgt atttctcaaa cgttcaaagg ttttgctgat aagcggacat aaaaaaccta
     8581 atgggacaaa aagtaaaata ttcaaaataa aactcaaact aaatccatca ctaaaaggaa
     8641 taagatttat gtttggatta aagaacgttt cccctaactg tgacagtctt atatattcac
     8701 tgaatgtagg gataccaaca atatgcgata gtgttaaaca taagtagtaa tacattgcca
     8761 gtgataaaat agatgttttg acctttggaa tatcactatt tttcttgaat attacaacta
     8821 agaaaatacc aatcaagata attcccaaca agaaaatagg attaattaac aataaatctt
     8881 tgatagcttc aaacagactg agttgaattt ctacacctga ttgattattt gttacaatct
     8941 ccatttgtac atacctcctc ataacatttc aattatttct aaaaaaaata gaagataaat
     9001 cttaaaatca tcctatcaaa atttttaaat ttgcctttat cagtttatac caccagttaa
     9061 ttcctgtctt acttctgtat ggtattcttg ggattctttc atcaaattag acaaaaaaat
     9121 ggttaccata tcaataaact ggttacgctc catatctccc gaagcaacca tcccctgaga
     9181 ataaatccgt atcaggaatc tccacatcta ctgcacctat cacaagttat ttgataacat
     9241 cctcagacaa tcccaacttg gatatatcga caacacccat tagaatacca ctgctgacca
     9301 tacttgtttt cctgctgata atttcaatca actgggaagt ttaaacgcta tcttttttac
     9361 aagttccttt ttagaaacat ggtagctatt atatgaatct gaatctcgtt gtctgggtgt
     9421 ttcagataaa gcatagatat gcaccttttt tgcctgtttt cattatatag aaaaaaattt
     9481 caaaatacaa taattatatt tttttcgttt aagcttagag cagttccttg atgaacaaca
     9541 ctttggaaac tgaatgattt acataccact taatacatta actcgattta acattaatta
     9601 taataatatt taaaacaaca actagggtat ataagaatga actttttagt tctttaatca
     9661 tttttttgta taaaatcaaa tctattttta taatttcaac aattttataa tttcaacaat
     9721 gaaaaaaggc ttatctctat tttgagacag cctcatttat tttataaatt tatatttttg
     9781 ttcatatttt tgagttattt aacaactata tttactagtt ttttaggtac agctacaact
     9841 ttaactatag ttttaccttc aactaatcct tttatttttt catcttctaa agctaccttt
     9901 tccatctcat ctttagatat atttgagtta acagttaatt ttcctctaac ttttccatta
     9961 acttgtacaa caacttctat ttcatctttt actaaagctt tttcgtcata tttaggccag
    10021 tctatatcaa atacacttcc ttctttacct atcatagtcc atagttcttc acctaaatga
    10081 ggggcaaatg gtgcaattat agttactata gtctgtacac cttcttttat aactgcttcg
    10141 tttatattat ctaactcttt atatttatac atatcattta ttaattccat aagagctgat
    10201 atagcagtat taaatccgaa tttttcactt aaatcagcag taactttttt aagtgtagag
    10261 tgtatagtat atctcatatc cttatcttgg gaatttaatt ctccaaactc tacatccttt
    10321 ttaaccacat ctgctaactc gtcaaccaat ctataaaccc tatttaagaa tctaaagcat
    10381 ccatcaacac cttgctctga ccagtccaaa tctctttctg gtggtgctgc aaataatacg
    10441 aaaagtcttg cagtatctgc tccatactca tctattatat ccataggaga tactgtattc
    10501 cctttagact tactcatttt agaaccatcc ataagtacca ttccttgagt aagtaagttt
    10561 ttaaatggct cattgaagtc taccattccc atactcttaa atgcctttac aaaccatctt
    10621 gcataaagta aatgcattat agcatgttct actccaccta tatattggtc tactggatgc
    10681 catctattaa ctaattcctt actaaatggt tcattttcat tattgctatc cacatatctt
    10741 aagaaatacc aagaagaatc aacgaatgta tccatagtat caacttccct tctagctggt
    10801 tttccacagt gaggacaagt tgttgacata aattgctttg aagtcgtaag tggagattct
    10861 ccttttccag taaattcaac atctgttggt aaaagaactg gtaaatcttc ctttttaact
    10921 ggaactattc cacattcatc acaataaacc acaggtatag gacaacccca gtatctttgt
    10981 cttgaaacta accagtctct aagtctataa ttaattgttc tctttcctct accttctttt
    11041 tctaacttat cgattattcc ttcaaatcct tctgaagcat ctaatccatt aaattcttct
    11101 gaatttatca ttttgttatc ttctgttatt acatcaatta tgtctaaatt atatttttca
    11161 gcaaaatctc tatctctttc atcatgtgct ggaactgcca ttatagcacc cgttccatac
    11221 tcaactaata catagttagc tatccataga ggaactttct tgccatttaa aggatttata
    11281 acatatctac ctataaacat tccttctttt tctacatcag ctgctgttct ttctatttct
    11341 gtcatagtat gcattttttg aacaaaagct tcaacatctg cttcatattc agtccctgca
    11401 accaattctt taactaattc atgctctgga gcaagtacca tataagtaac tccataagtt
    11461 gtgtctggtc tagttgtaaa tactgtcata gatttatcag ttccatctat atcaaaaact
    11521 aaatctgctc ctgtactttt acctatccaa tttttttgca ttgttttaac cttttctggc
    11581 catccatcta atgtatctaa gtcattaagt aattcttctg caaactcagt agtcttaaaa
    11641 taccattgtt ctaaatcttt ctttaatact gttgctttgc atctctcaca tgctccttga
    11701 acaacttgct catttgcaag aacagtctca caagaaggac accagttaac atatgatttt
    11761 ttcttatatg caagcccatg ctctaaaaac ttcaaaaata tttcttgtgt aaatctatag
    11821 tattctggcg ttgaagttgc aacttcttta tcccaatcat aactaatacc taataaattt
    11881 aattgctctt tcatttcctc tatattttcc attgtccatt tatgtggatg tattccatgt
    11941 tttatagctg cattttcagc tggtaatcca aaagaatccc atcccattgg atgaagtaca
    12001 ttatagcctt ccattttttt gaatcttgcg acaacatcac ctatagaata atttctaaca
    12061 tgtcccatgt gtatttttcc agatggataa gggaacattt ctaatgtgta ataattaggt
    12121 ttttcagttt gtgcagtatc cattttatac tgattattat ctttccaaat tttttgccat
    12181 ttcgattcta cttctttaaa attatatacg ctcatatttt gcctcctatt tttaattgtg
    12241 tataactacc ttatttagta ttatttactt ataatttcca aataattctt tgaaaataaa
    12301 aaatcctcgt cactaaactt acgtttaggg acgaggataa atcttcgcgg taccacccta
    12361 attagcctac tacatatata gactctctta gatagctttt aatccagcca tggagaatag
    12421 attttaatct agtaagttca aagttatata atattagttc tcaccttcca ctaactctct
    12481 gaaaaaatat aatcttttac tgctctagtc tattcaattt aatataattt ttgaaatttt
    12541 ctaattataa taacatatat tatcatgttt atgctaatgt gtcaatatct atataaggtg
    12601 catctttcca taatttttct aaattataaa accctctatt ttcctcatta aatacatgaa
    12661 ccattatgtc tccataatca aggagtaccc aagtttgagt tccttgtcct tctttacctc
    12721 ttggctctaa tcctagtttt gataattcat cttctacatt gtcagcaata gcttttacct
    12781 gtctctgaga agatgctgta gtaataataa aataatcaca caaactagaa acttttccta
    12841 tatttattat aactgtatct tgacctagtt tatcttctat ggcatcatat gctatttttg
    12901 tcatttgttc cactgtcata taaaaattcc tcactttcct aattaaaata cacttagtta
    12961 ttgtaacata ttaatacgat tttgtaacat agtcaaattt aaatttatta atatgtttgc
    13021 ctttatatag cttttttata ataacttttc tttaattaga tagtttcttg ccataactgt
    13081 tcttggatgt atctcttctt ttttattgat gacaaacatt aaagtattat taaaagaagt
    13141 taaaagtgct tcatcaagct tccctccata tgctaattct cttaatgtat ctacaactgg
    13201 gaattttctt ccttcttcaa ttaaatcagc tatgtaaatt attttttcta aaagagacat
    13261 gtcctctctc cctgttgtat gatatttgat tgcatttata atatcttcat cttctacttc
    13321 aaattcatac tcgcatatgt acgccccaat tacactatga gacaaggaac gatttccatc
    13381 ctctattggg tctaaatata tttcatactt atttacataa tcctctattt ccttgtcact
    13441 taaatacttt gcacaatcat gaatcattcc tgctaagtaa gctttttctt tgtcacatcc
    13501 ataaatctca cataattttt cagcacattt tgcaacattt tttgaatggc taagcctccc
    13561 cactggtagc atttgattta gtctttggtt aatattttct aagttcattt aatcatctcc
    13621 atattgatat agtttatttt catataaata attttctaca ttttcgggta ctaagtaacg
    13681 tattgacttg ccttcattta gctgttccct tatatatgtg gacgatatat ccagtgatgg
    13741 aacataaact gttataatgt cagcattata cttcttagtt agtttttcta tagtctcttg
    13801 tgaccttaac aaactaattc ctggtctagt tgcggctata aaagtagcta actcaaagtt
    13861 tttctttaca tctttccact cttcaacact acaaattgca tctgcacctg ttataaaata
    13921 aatgtctgca tttttgtatt ttttctttaa gtattttaat gtatctattg tataagtcct
    13981 tttctttctt tcgatttcta cttttgaaac taaaaaatct tcgttgcttt cagttgctag
    14041 aagtgtcata ttatatctat catacttatc tgtagtgata cataatttat gtggtggatt
    14101 tcctgatggt ataaagatta ttttgtcaat gtcatacttg tctctaataa attctgctgt
    14161 tgctaaatga gcatagtgta tagggtcaaa agtacctccc aatataccta ttttgatttt
    14221 gcctttatgg cgattaaatt tctctagttt ttcagtattt ttcaactctg ccatcttaac
    14281 tagattttca cttctcatat tttgtctcct tttaatgtta taatactatt gtaccattat
    14341 tttttatttc ttaaagctta taatttgttt ttttgggtat ataattatat ttatatgcta
    14401 aaaaacactt taaaaaataa ttatttaaca tgattctgct ttacttttta ataaaaataa
    14461 ctttttacta ttttgtctta attttgataa aatataacat acaaatataa gttttttgtt
    14521 aaattttatt agttgctttt gttaatataa ttacatataa aaaaggagga cttatgggta
    14581 taattacaaa aatagaacaa caaaaaagaa atgatgatag agttaatatt tatgtagatg
    14641 ataaattttt tattgctata tttaaagaac ttgtttatac atttaattta aaaaaaggga
    14701 atgaaataaa tgaagaagaa ttaaaaccta ttttagatga tgaaatgtat ataaaagcta
    14761 aaaataaagc attaaatatt ttatctcatg ctgaccaatc tgaaaaaaaa ttaaaagaaa
    14821 aactatcatc agaatttgat gaaaatataa ttgagagggt catagatttt cttaaaagtt
    14881 ataatctcgt aaatgacagt gtattagctc aaaaaattgt taacacaaat gttaacctaa
    14941 ataaatgtgg caaaaacaga attaagcaga atttatataa taaaggtatc aatagaagta
    15001 caatcaatga agcagtatct gaattagaca aggacactga atttgaaaat gctatgtatc
    15061 tagcaaaaaa aaggtatgaa agagtaaaga aagaagataa aaagaaaata tatcaaaaaa
    15121 tttctcaaca tctttcctat aaaggctttg attatgatat tattaaaaga gttttaaaca
    15181 aacttttaaa ttttgatgaa tacgatatat aagtataaat actagggagg taaattatga
    15241 aattaatcat tggtggctta agctttttat taggattata taatatatat caattataca
    15301 gagaagatag tatgagataa atattatttt ttaaatgtaa tatttattat ggaggagaaa
    15361 tataatgaaa agtcaaaaaa gatttaaaat tttagatatt gatgtatacc tacaaccatt
    15421 tgaatctgat ataaaaaagc gaatgaaaca ttatgaggat atgaaatcaa aaacattgaa
    15481 aaactataaa gattttagtt cttttgcaaa tgctcatctt tactatggat ttcatcagac
    15541 aaatgatgga ttcttctata gggaatgggc tccaaatgca gatagtttgt cactaattgg
    15601 tgactttaat aattggaata gaaaatctca tcctctaaga aaaattgggt ctggtaattg
    15661 ggaaatattt attcctggtc aaaatagctt acctcacaaa tcagaggtaa aggtacaagt
    15721 tactgcaaat ggaaaaacat ttgaccgtat accattatat ataaaaagag taattcaaaa
    15781 agattttggt ggatttaatg gacaaatatg gcaaccaaaa actccattta tctggactga
    15841 caataatttt gacttaaaaa acataacttc tccactaatc tatgaatgtc atataggtat
    15901 gtctactgaa agcgaatcta ttggaactta taatgaattt actgaaaaaa tacttcctaa
    15961 gataaaaaaa gctggataca ataccattca gcttatggct attatggaac atccatatta
    16021 tgcatctttt ggataccaag tttcaaactt ttatgcaatc tcatctaggt ttggtactcc
    16081 tgaagactta aaaaacctca taaacactgc tcattcaatg gggattgctg ttttattgga
    16141 tttagttcat tctcatgctg taaagaatac tttagaagga ataaatgagt ttgatggaag
    16201 tgaacatcaa tttttccact caggttcaaa gggaaatcat cctgcttggg gtacaaaact
    16261 ttttaactat ggtaaacctg aagtaataca ttttttgctt tcaaatataa aattttggtt
    16321 aaatgagtac cattttgatg gctttaggtt tgatggtgta acttcaatgt tatatcataa
    16381 ccatggtctt ggagtttcat ttgatagtta tgaaaaatat tttagtatga atacagatat
    16441 tgaagctata acatatctcc aatttgcaaa tgaattaata aaagaaatta aacctaattc
    16501 gataagtatt gcagaagata tgagtggaat gcctggtatg tgtatcccta taaaagacgg
    16561 cggaattgga tttgactata gactcgcaat gggagtacct gatttttgga taaaaactat
    16621 ctctaactta tctgatgaag actgggattt gggcaaaatg tggtatgaac ttactactag
    16681 acgacctgga gaaaaaaata taggatattg tgaatcccat gaccaagcat tagttggcga
    16741 taaaacaatt attttttggc tagctgataa ggaaatgtac tggaatatgg aaataaactc
    16801 aaataaccat gttatcaata gagcaatgtc tcttattaaa ttaattaaat taataacttt
    16861 ttctctagca ggtgaaggat atctaaattt tatgggaaat gaatttggac atcctgagtg
    16921 gattgatttt ccacgagaag gcaacaattg gagctataag tatgccagaa gacaatggag
    16981 cctttcagaa gataacaact taaagtataa acaattatta agttttgata aatctatgct
    17041 tgaacttaca aaatacagtg atatttttat ccaaaatagt catgaactta tacatatgga
    17101 taatgataaa aagattttgg tgtacagtaa gggcaaatat ttatttatat ttaatttcca
    17161 ccctaatcta atacaatcag ttgatatttc aaagtttcaa aatacaaact acaaaacgat
    17221 attaaatact gatatggtag agtttggagg aaacacaaaa aaagaaaact taagagatta
    17281 tgatgtatac tttagctcaa ctcctccttc ttctaaaatg cctattgcct ctcgtacagc
    17341 aatagtgctt ttagataatg gtatttaaat atgagccaaa tatattagga aactgcaaat
    17401 atagtccagt ataaggcaaa aaaataaaat aattaaagca tggcaatata cctgttcaac
    17461 atgctaaaaa gacacattga caaatcatta tgtatttgct aagataaaca taccaaatga
    17521 ttgttttgag gagtgagctt tttgggaaga aaaaaagaac ctgataatac tatacaaaaa
    17581 atacttgata tttcacataa gttgttctta gaaaaagggt atgagcagac aacgattcaa
    17641 gatattgtag ataatttaga tggcctttca agaggtgcta tttatcatca ctttaaatca
    17701 aaagacgaaa taattaaggc aatcacaagt cgtttgtata atgatggatt ttatggatat
    17761 gatgtaaaaa atgatgaagg aaagaccgca ttagaaaaat tacaatatag attgcttcat
    17821 gcttatgaac aacacaataa acaagacatt tttttaatgt catcatcact attgcgtaat
    17881 cctaagtatt tagctacgca gtttgatgag attataaatg atattgtgcc ttggataaaa
    17941 gcattgattg aagaaggaaa tcaagataat tctatgcaag ttaaaaatcc agagattgct
    18001 gctcaaatgt ttggttttct tctaaacaca tggtgtattc caacagttta tccaggtaat
    18061 ccacaacaga tgatagaacg ttttactttg tttggtgagc aagctgcttt tatgggtatt
    18121 tcttttatga atgataagat aatgtgtgaa tatcaaaaat ttgttaataa attttctaaa
    18181 tagtaaatat aaaactgcct taatatcggc agttttatat ttacacaaaa caaacattta
    18241 gttggtattt ttaaaaattt aatttatttc agtacatgca aaaggaggtt gctatgaaca
    18301 aactaattaa agattgtgta aactttttta atgattgtgg cttttcatat tcaatatgtg
    18361 gtggatatgc cctagaatta tttgcgaata tgcatattcg cccacacagt gatattgaca
    18421 tatggatttc tgacacagat aaagaaaaga gcattcagta tatgcttaat caaggatggg
    18481 atatatatga gcccttgggt aattatttat tacgacctat tatcgacctt aacaagcaac
    18541 atatagagca aatttgtgtt tttgcgatta agcctgattg ctcatttatt gaattaaaaa
    18601 aagtcgagga tgataactat aaaatgaata tacagtgtga cgaacagtta cagttcgatt
    18661 ttattgaatt gatatataat ccacagaaag atggaaaatt tcttttttcc caaaatcaaa
    18721 gaattataag agatatggat aaggccagac tgataacatc agataatatc ccatatatgg
    18781 ctcccgaagt ggttttgttt tgcaaatcaa tatacataga taggcttggt tatcaaaaag
    18841 acttcgatgt aacagtccca ctattatcac aagagcaaag ggattggctt gtaaatgctt
    18901 taataacagc atatccagat ggacatgcat ggattgacca attggcaaat cagtattaag
    18961 ccttttagct cccgaatatg acattatgat aatccacact ctaacagttt gttggttttt
    19021 ctagtatata acactcatat taaaataaac actaaaagcc aaataacaat ttaaatacaa
    19081 aatgttattt ggctaattta gtttgatact atttaactat cttttacatt cagttctata
    19141 atttccaact tttaatttgt ggtattatat tcatcttaac agtttgattc tttaaagctt
    19201 ttctaaattt ctcagttgaa gaatctttaa acattttact agaagcactc ttgaggtctt
    19261 ctatagattc ccaatgttgt atcataatcc acttttgaga cttttcatca tataaaagct
    19321 cagtatcaat aaaaccagat tgaatagaat gaaattttaa ttctaagtca tttacaattt
    19381 ctataaactc ttcttttgat aaattttctt ccacattaaa ctcaactatt tctgtaataa
    19441 ttttcatatg taaaacctcc aatttatttt cctatatcat atcaaaaaat aaattggagg
    19501 tattgtaaaa aatcgacagt ataattataa atagctgtac tttatatttt ctttaatcgt
    19561 cttattctca ccactaaatt taattggtga cgtccctgaa aattttttaa attcttttat
    19621 aaagtgtgct tggtcatagt actcattttc ataaataaaa tcaaaaagtt catcatcttt
    19681 ataattataa ataagttgat tgcttgccat tttaaatctg taaattctct ttaaaatctt
    19741 aggtgtatac cctgtatatt ttaaacagat tctttccaat gttttaatat ttatatttgt
    19801 atcatcacaa aatgctttta tattgctata tctattaaca tatataaatg aatttagaag
    19861 ctttacatat ttatttgaaa ttaaatcttc ttctaatatg gataataata cttcttctaa
    19921 atataaaaca attttttcta ctgattgtgt tggatttaat gactcttcca atttttttgc
    19981 aaatagctgt gatactgctt ctaggtcaac agtttgtctg ttaaactctg aaattggtat
    20041 ctttaaaaat agatagagac caaatggata aaaagaaatc cctataacac gtatatttcc
    20101 atgttgaata ataaatccat gtttatccct tattccatta aaatgcatat tactagcagt
    20161 atagtcttga ttttcaattt tatattccat aacatcagaa agattgagaa taatatctat
    20221 actgtctgtc ggaagtaact tattatttaa cagtatattt gattttgtct caaaatgcca
    20281 aataaacttt acccacggct ttaaacgaac atttttgatt gaatatcttg taactgataa
    20341 cattgtgaac taacctctat actaaaattt tttaattatg tactccatcc taatattata
    20401 cagtataatt tatgctatca taaattttag ttcactttat atttatttta tacatttttt
    20461 caatacctta gaaataggaa gcgctattat aagacctatc aatacttgca ttaaattacc
    20521 tggtattgaa gtaagaggta ctataaaatt accataaagt ataacttctg ttacataata
    20581 tccaaatagc atccaaattg atgagacaca tattcctatt acattgatta aaaaattatt
    20641 cccattatta ccatttgccc atgcaatctt tccaagtaaa taacccataa ctcctctaac
    20701 tataaaggta aacggtgccc ataaagtcca cccagatatc aaatcaaaaa gtgacatacc
    20761 aatagcccct gataaagcac cttttttacc tccaaatact attgctgata tgaacaacat
    20821 tgcagttcct aaatgcacaa gcccaccatt tatagatatt ggtaatctta tgtttataaa
    20881 tttagttgca ataaatacta atgctattaa tagtgaggtt tccaccatgt ctttcgttgt
    20941 aaatttttgc ttaactgtaa cttccatact atatccccct atctattaaa aataatactt
    21001 attaaataaa tttaacaaat ttccatttcc tttgaatcct aatgcactta aacttttatc
    21061 caaaacattt agtacatgtt ctattttatt tagatttgca ttctctccca tatgacctat
    21121 tcttaaaata gtatccatat attgatttag tgatgttgca acaagtgtat tataattttt
    21181 aagcatataa tcagtaagtt ctaaagctcc tatactttca ggaactttta tagctgtgac
    21241 tgtattagaa tatccttctt ctaaaaatag ttctagacca tattcctcaa tagattttct
    21301 aacactataa gctatctttt catgtctatt taatacattt tctattcctt cttctaatat
    21361 attatcaagt gctttatcaa gccccattat gtcacttatt ggcattgtat aagggaagta
    21421 ttttttttca taatagcctt cccatatatt taaattacaa taaaaaccta ttacatcagt
    21481 ttttctattt tttatacaat tttttgcatc ttgacttatt ccgactatag taagtcctgc
    21541 tggtgcagaa atagcttttt gtgaaccacc taatattata tctattttag attcatctac
    21601 acttaatctt tctcctacca tacctgctac agaatcaact acagttaata ttccatattc
    21661 tttaagtaat ggacatattt tgcttacatc atttaatacg ccagttggag tatcacaatg
    21721 cactactgtt gcatatttaa aattactatc ctcatctaaa aatgctttca attcatcaat
    21781 atctatactt ttagtatatt cacttgaaaa aagcacatac tccccaccat acattgttac
    21841 aaaatcttta aaaccttctc catatatacc attgtcaatt acaagtactc tatctccttt
    21901 ttctgtaagt gatgcacatg ctgcttcaag acctaatatt ccttcaccac tcaatatgta
    21961 aacatcgttt tttgttccaa ttatattacc aaacttctcg catgtctttt tataaaattc
    22021 aacaaaatca atatctatat ctggatttgt tgttttttct gctcttgcta atcttacatt
    22081 ttccctagtt tcagttggtc ctggtgcata attaatcttc ttattcatat atatcagctc
    22141 ctatttattt tctatacgat tattatacaa aattttcatt ttatatggta caattttata
    22201 cttttttaga attgtaccgg tacattttct aacatgaata atatcagtat attagatata
    22261 ttattgatta cataataaaa tacagagcaa acatctgctt aaattgtttg ctctgtacta
    22321 tgctttaacc tatttaatta tgaatctctt taactatatt tttttatatg ttttttgcta
    22381 gttaaactaa ccataaatat ttgcatttta ttcactgtat cttactctat caataagaga
    22441 ttctttatta aaacttcgtc ctatcaaata agttgttata aattgagcta taagaataca
    22501 cacaatcatc aacaagattg gtactattgg caaagaatat gttgcataag ataatccagt
    22561 cttttttaga aatataacag caatataccc taatatacct ccaaatagaa tacttcctat
    22621 catcattcca gaagtgtaat acattgcctc tgaattaagc attttcacta attgtttatt
    22681 agtaagacca atagcttgaa gcataccaag ttcttttttt ctagtaacta tgctagttat
    22741 cattgtgttg acaagattca taaatccaat cacacctatt atgcctgtta gcgtatatcc
    22801 cattatcttt ataaatgaaa tagtagcctt atttgactca attctactat ctataaagtc
    22861 agtctctaaa aatccattat ttttagcaat cttcttgata ctatctttga tttcttgata
    22921 ctttccttct tctgtatata ttcccaagct actagttgaa tcgtatttca aagttctatc
    22981 tataaaatct ttccctatac caaaacttgg aacccccata gctattgctt gaactttaaa
    23041 ttcttttttt atctttttat ctccatcata taaagttaat cttattttat ctcctgcttt
    23101 tactcccatt tcttttgctg tatcaacatg agtaattact atttcatctc cagtttgaag
    23161 tctttcaaga tttatttttc catctattat attcttgttt aatgatttta catcattttc
    23221 atttatactt tgtaaaaggt catacttaaa ttcaacatca tagtcctcca taccaatttt
    23281 tacacttctt gcagattcta ttcttttaat tccttccatg ttctttattt gattaaaaaa
    23341 atctttactt agaggattat ccatttgtaa aatattcaaa ttatctttag gatttttatc
    23401 actgttcatt tcataaccag atagtctaac ttctatatca taaggaaagt gttctcttgc
    23461 cattttctca gcatcaaaac tttctaaggc agttgatact gttataaata tagttccact
    23521 aagtataagt gatgccaatg tcatgtaagt acgtttttta tttctttcta aattggcatg
    23581 tgataatctc tttagattta tatttttata tccttttctc ttactcttat tacttatttt
    23641 atttcctgta tatcttactg cgtcaacaat ggatactttt gatgctactt tcattggttt
    23701 taaaagtgat aaaacaacag atataaagct tattaccaca accgataata taactggtaa
    23761 tcgtgatgat tttacatcta tatccataaa tgattttatt ataatatttg caagtacata
    23821 gcctaaaatt attcctattg gtattgctat tccggctaat atgaaccctt ctttaaacac
    23881 tatatttttt atttgtttct tagttgcacc aattgctcta agttttccaa attcttgaac
    23941 ctttgtaact attgaaatat aaaatatatt gtatattact aaaatactag ataatacaat
    24001 tactaaccct acaaaaactc cacccataat cgtttccata tctggtttta aagcatttat
    24061 ataattttca tttacagcag tattaatagt atccagtcct atatcattag caattttatc
    24121 taatttttct tttgcttgct ctattgataa attactttta tcattaaatt tcacataaat
    24181 attaaaatct tcttgtgaca tatctctagt atttctcata tatgattctg atataatagc
    24241 ataataatat ttacctgctt cagatatttc gctagttttt aagattccac ttataatgaa
    24301 ctctttttca atttttttat catttttata gtcatcataa gatattttta tcttttcacc
    24361 taaatcttta tttttataac caagtgcctt taaagctcca ctatctaaca caatttcatt
    24421 ctcttttgat ggcaattttc ctttgataaa ttcaaaacta tttaatttca aagcatcttc
    24481 attcatgtat gctagagaaa tatttgaatc atcttccagt ttttcaacac ctactccatt
    24541 catttcacca gttaattcaa catctgcatg attacttaat atatcagcct gtttttcatc
    24601 tacatttgct aatatacctt gataattgcc tgaatacttt atagtatttt ctttttgata
    24661 tgctcctgca tcaacaatat aaattccaat agaagaaagc attaaggttg aaagtattat
    24721 agtaattatt attagaatac tttttgattt attttgcttt aaattacttt ttgctatttt
    24781 agtagtatta atcattttta tcaccaacct ttgacaccct gccatcttct atgaatataa
    24841 ctctatcagc catttgggct atactgtcat catgagttat cataactaga gtttgactgt
    24901 acttcttaga catagatttt aatatactca taacctcatc agacgtttta gaatctaggt
    24961 ttccagttgg ttcatcagca agtattatag ctggtcttgt agctaatgct cttgctattg
    25021 ccaccctttg ttgttgacca cctgataatg tatttggtaa aacgtcgtgt ttattttcaa
    25081 gtcctaatga ttttaaaagt tcttttataa aagattcatc tacttctcta ccatctaaac
    25141 cgattggcaa cactacattt tcccatacat taagagatgg aattaaatta tagctttgaa
    25201 atataaaccc tatttttctt cttctaaata cagcaagttc ttcttctttt aatgtaaata
    25261 tatttttatt atctatatac accttcccag atgtaggtat atcaagacct ccaatcatat
    25321 gcaaaagtgt actttttcca gaacctgatt ttcctattat tgcaacaaat tcaccttcat
    25381 ttatttctaa gtcaacattg tccaaagctc ttactaagct ttctcctttt ccataatgct
    25441 ttgataaatt ttcagtatat agtattttca taaaattatc ctctcattct aagttatatt
    25501 actccatatt ttattaattt tttatttctg gagctgttta tacttatata ataaatgtag
    25561 aggcttacat tttcctttca tttaatatta catagttgta agaaacaaag aaaacttgct
    25621 ccctattcct acttttgaag aaactataat atttccacct tgttcttcta aaatctttct
    25681 acttaaatac aatcctaccc cactaccttc tacagattca atttcatcag cagaacctct
    25741 ataaaaacgt ttaaatatat tattaaactc atttttttca atccctatgc cattatcctc
    25801 tattataatt ttaaagaaat tagcagtttc ttctacagat atatttattt ctccatttac
    25861 ctgtgtatac tttacagcat tgtctaatac attaaaaata ctctcctcag tccacttttt
    25921 atcatgtggt ataattctac tgttaaattc atttaaattt agtgttatac ttttactctt
    25981 agccttaggg gtaacacttt ttactgcatt tagaatagta ttttttatat cattatcttc
    26041 tttttttatg tttatcatgc taatttctaa ccttgatatg ttcactaaag aatttattaa
    26101 attttctaat ttatttatag aagccttatt ggttaataag aactcgttgg cttcatcttc
    26161 ttctaattct tcttctataa gtaatgtatt gtataatttt aaggatgcta aaggagtttt
    26221 taattgatgg gaaatatctg ttactaatga ttttacactt tctttttctt tttctaattt
    26281 aataaacttt atctttaaac ttctattaag ctcatataga cagttattta tcttactaaa
    26341 tatgccttct ttaaagtatt cattatattc tactagataa ccagtttctt ctgactcagt
    26401 agtgtccttc aagtagtttt cttgtgacat cttatctact ataaaataaa ttttactcaa
    26461 tcttttattt atgtatatta taaaataata tattatacct ataactacta taaacatcat
    26521 taaaaaaata aaaaatgatt ccttaaaaaa agattttaag tataagctaa aatttttatc
    26581 atttgacatt ttattttcca atccatagcc aaatttctta aatgcctttt ctccagtaga
    26641 caccttacta taatcagaat tataaataga atttactata tctatttcat cattaggata
    26701 tttttcaatc aatattccag caatattttg agtatttttt atttgatgtt catacaattt
    26761 atgtaatctg ctatattcaa aaagtataaa tacaagggtt actattagta cagataaaac
    26821 agaatataca ataactcttc tcattatata atcatctttc acacttaaac catctttgag
    26881 gttcatattt tttagcattt ttttatactc ctttctcccc acatatatcc aacccctctt
    26941 actgttttta tatatttagg ttcagatgga tttttttcaa ccttttgtct aagtcttctt
    27001 atatttactg caatcgtatt atcatctaca aaattaccac tactatccca taaagattct
    27061 aacagttgct ctttagtcaa tgtctgcata gaattttcca tcaaatattt taatagtttt
    27121 gtctctgtct tacttaaaat tatctcttct tccttatcat ctgttcttat aattaattta
    27181 ttttctatat aataaaagaa taaatcatca caaactaata gagtataatt ttttactgta
    27241 tttactcttt tcataagcgc attcactttt gatattaata ccatcaagct aaaaggcttt
    27301 gtgatataat catctgcacc taaatcatat cctgtgacaa tatccacctc ttcatcaaga
    27361 gctgtcaaca ttattatgta aacatcactt ttctttctaa tctcctcaca aaagtcaaaa
    27421 ccactaccat caggtagacc tatatcggaa ataattaagc atatctcttc ttttgcgaaa
    27481 atattttttg cttcttctat accaaatgca ctaaaaacat tgtatccttc tttttttaat
    27541 ttaaaactaa ttcctctatt taaagatttg tcatcttcca aaagtaatat attattcatc
    27601 cctatatcct ccatcatcat atatactagc taaattatat catactaata aaatcatttt
    27661 tttatcaatt tgtaaatata tcagaagttg ttaatatgat ttcatttact tgaataaaaa
    27721 ctaaaaatcc ccataatact atgccattta gtgtaattat ttttcataaa atacaatttt
    27781 atttaaaagt aatcatgtta aaacataaaa caaaggaaat tagtatttat ataactaatt
    27841 tcctttgctg tttactatta tctaaaatta aattactatc tactagtttt tgctcattaa
    27901 tttttatttt gactttttat cctttaactt tttttgatta aaattcaata aacatatcaa
    27961 tgtacttgaa actataaata taattatact atttgaaaaa cctaaatctc ctgttttagg
    28021 agatttttct ttagcttctc ttttagatat tcctagatta gaactttctc tagaacttgt
    28081 tttatctaag cttttatttt tatcactatc agagcttttt atattattag atagattctc
    28141 ttcattatca ttgatatttt tttcattttc acttaatatc aaatcactct catgattctt
    28201 gcttattaac tcatctttag atttaatacc aattcttcca tctacatttt ttgatatttc
    28261 ttttttgtac tctatatatt caatgactgc actctctaaa tttccaaatt cctttagtat
    28321 tggctctttt gaaaaacaag gaaattcatc tccacctgat gctatataat cattcgttgc
    28381 aactacatac tttttattta aatctaatgg ctttccttct ttttgaatat ttgttatttt
    28441 ttcgccttct ttttgtttag gattaaagta atatgaaatt cctcccactt gcaaaaaggc
    28501 tgaacttttt tctgggtaaa gttttactcc atgctccaat acatctttaa tctgtgctcc
    28561 tgtaagttct ttggtaacta tagtattgtt aaaaggaaat acatctacaa tatctcttct
    28621 tgttatattg cctttttcta tcgtatctcg aatattccct ccattaaata aagaaatatc
    28681 agccttagtt ttatctagta aaatgtcact tattaaatta cccaaattag tttcttttgt
    28741 ccttacattt tcatatgaac catctagagt atttgtagtt acccctataa ctttatctaa
    28801 tattttttct tgttgttctt ttatttcatc aaccttttta cttacagcgg agtcaagctt
    28861 atactttaat gcttcttctt ttccaattaa tctaactgat ttattttcta tttttatatt
    28921 ttctacatca ttagtatcca aagttagttt tatctcgcca atattttcta aatattgtcc
    28981 tgcacttaca atcaatgtat cacccacttg tttaccattt tcaaacttag tgtggctgtg
    29041 tccatcaata atcaaatcaa ttccttgaac ctcatttgct atatctatac tatttggctt
    29101 acttaaacta tttgtaccaa tatgacatat tgcaactatt acattggcac cctttccttt
    29161 taattcattt acttgttctg ttgcactttc tataggattt ttaaactcta atccttccac
    29221 atttttaaat ccagttttgc tctttgtttc ctgggttgag agtccaaaaa atcctatttt
    29281 tattccatct atttctttta tatcattact atcaaaaact ttttttccat tttcaaaaat
    29341 atttgatgat aaaaatttta aagtattctc tcctaaatta gcacttttag ataactcaaa
    29401 cagtctatct tttccataat taaagtcatg atttccagga gtaatatagt catatccagc
    29461 acatttaatt aattcaattg cacttttccc tctatccata tttactattg gaagtccatg
    29521 caaacaatct cctgcatcta ctaaaattga gtttggagtt tcttttttca atgtggctag
    29581 atttcctatt tgtatatggt catcaccttc agcatacctt ccatgtatat cattagtgtg
    29641 aaaaatggtt atttcttcaa atcgctctag cccataagaa ataaaactct gacttgttgt
    29701 aattagaatt ataattacca aaattaaata ccttctaatc ttcaatataa attagcctcc
    29761 tcaaattagt tttagcttta atataaaatt tatattttac ataaaacttt ttagataaat
    29821 attaaactat agtaagatta attagtgtaa tttttaatat ttatctatca atttaatttt
    29881 gtccatatcc aattagtttt aatctaatta cattttttca catctatatt tttcttttat
    29941 tatataaaat tattatttta aaatcttttc aactggtctc ttttaaaagt ccattgaggt
    30001 attgtcaaat caccttcaaa atctaaacta taccaaggac tcaaatttgg atttttacga
    30061 ttaataagaa gttgcgtttg ttgtgcaggc atatagcttt gggctatcat aaataccttt
    30121 tcaccagtct tttcattttc tgacatatcc ataattatac ttgcatgtcc tggacttcca
    30181 ccaactataa acacatctcc tattttcata tcctcaactt ttacaggctc caattctttt
    30241 tcaagagata acgttcctga atatgcaaac actatatcca taaactttct aaaactctca
    30301 taagatgttg aatattcagt tgctttatac cagcttgaac cactatcttt tactgaaatt
    30361 ctatatcctt gtgcccattt tgaatacttc gccttaaaac catcaacaaa atcaaaactt
    30421 atttcatcat atagtttatt ctgatacaag tattctgctc tcataagcat aattgcatct
    30481 gcacattgat gtaaatctct attgccaata tcaacatcaa atacactatc ataaatacct
    30541 tttgattcct tagttcttcc atcataatac tttactttct ctccataatt ttttagctta
    30601 gtattcctaa gaaatgattc aaaactacct ttttctacat caactctttt aaatcctttt
    30661 ggtggctcat acctatcttt caatatattt gcatctttat gtactattat aggctgttca
    30721 tcttttttag aattttgaat tttcttagaa ccttcaacca cttttttatc ttctccgtta
    30781 ctacaaccaa ctaaggttaa tgtaatcaat gacaaaatag taattttctt taatactttc
    30841 attaaatttt cctcctttaa atgctcctaa atataatttt cactttttgt tttccaaatt
    30901 tttatacatt tctatataaa aactttattt gacaatattt cttgactcaa atacacattt
    30961 attgttatat ttaatgttaa aataattata ataggatatc ataataaaaa caaacaacag
    31021 atttgtgtta attttagaaa ggggaaaaaa tgatagattt aactttactt ggatgtggtg
    31081 gaaatgtacc tatgccaaac agatttctat cctctgtatt tataaactat aaaggtagaa
    31141 aaatactaat tgactgtggt gaaggtactc aggtatctat gaagctaaaa aaatgtggct
    31201 ttaaagatat agacttgatt tgtataaccc atttacatgg tgaccatata tttggactct
    31261 taggactttt atcaacaatt ggaaatagtg gtcgtacaag tgatttaact atagttggtc
    31321 cagttggaat agtcgattgt atacgttcta tgagaaattt agtagaatat gtaccataca
    31381 ctttaaaaat tatagaaaac cctcaaggca atttttcttt agataataaa gttttaagaa
    31441 atttagaaat ttcaacaatc agtttagaac actctataga gtgtttagga tacagtttta
    31501 attttagaag aaaccctaaa tttgatatag ataaggcaac taaaaacgaa gttcctaaaa
    31561 tattatggaa caaactccaa gaaggtcaaa atatagtttt agattcaaaa caatacactc
    31621 cagatatggt cttaggagaa ttgagaaagg gagttaagat aagtcttaca accgatacaa
    31681 gacctataga atcaatacca gatttcataa aagatagtga tttatttata tgtgaagcca
    31741 tgtatggtga tgatttagat atatcaaaag ctgttagaaa caaacatatg acttttagag
    31801 aagctgctaa tcttgcaaaa cttggaaatg tcaaacaact tttactgact cattttagtc
    31861 cttctttaga catacctagt atgtatttag aaaatgctac taatgttttt gaaaatacta
    31921 ttcttggaga agatagatta agcttgcgtt taaattttga tgaataattt aatggaatcc
    31981 ttatttctaa aaatttggaa taaaaatttg gaataaaaat ttaggaatga attttaccat
    32041 gataaaaata gtttaggtaa attcattccc ttaattgctt gtcaactata ttagctataa
    32101 tctaaatatt atttagatac atttccagct acatttaaaa catcccatgt tcttgcaaat
    32161 ggtggagcat aacataaatc taacattcca agttgatttg tggtcatttt tccaaagata
    32221 gcagctgcca atacatttgc tctttggaca gcatccttaa acccagccac ttgtccgcct
    32281 aaaataactt ttgtatctgc atcataaata agctttacat atattttatt tcttcctgga
    32341 taataatgag tttgattata atcagaaata aatttagatt tgacatttat gcctaaatct
    32401 ttagcttgct tttctgtaat tccagttgat gctgcctcca tatccataat ttttatacag
    32461 cttgaagata gtgaaccttg ataagatact tctcttcctg ctaggttttc tcctactatc
    32521 ctacccaatt tattagctcc agtagctaaa ggaacatata cattttcatt acttactata
    32581 ttctttatag ttgcacaatc tccagcagag tatatatctt ctacagaagt tcttccatac
    32641 tcatcaacta ctatagctcc attttttagc atttttatat tagtatttga caaaaactcg
    32701 gtattaggtc tcacaccagt agcaattatt actacatctg tatctatttc ccctttgttt
    32761 gttataactt tttctacttt atcttctcca caaagttcta caaccatttc atccaagtgc
    32821 aaattaacat tatgtctatt tatttcttct tctaatacat ccgtcatttc cttatcaaat
    32881 acttgtggca atattctatc ttctaactga attacatcta catctttacc taatttctta
    32941 catgcctcaa ctgcttctaa ccctataaaa ccagctccta ttattgtcac tcttttatta
    33001 tcttcattac ttaaaagttt ttttaaatat tctccatcat ataaactttt taatgtagaa
    33061 acattcttta attttatgtt ttttatagga ggcataatac ttcttgctcc agttgctatc
    33121 atcaatttat catagtaatc ttcatatatt tcatctgttt ttatgttttt tacttttatt
    33181 ttcttagatt cactatcaac ctcaacgact tctctaaata tatttaaatc aattccagct
    33241 tctctaagtt tctctggtgt tcttgctaat aattcatcag catcattaaa aaatccacca
    33301 acaaagtatg gtaatccaca agcaccaaaa gatactattt cagttttttc ataaacaaca
    33361 acttcatact caggttttat tctttttaat tttgctgcag cactcatacc agctgcaaca
    33421 ccaccaatta ttattactct cattctatct ctcctttgat gtctagttaa tttcttcact
    33481 tattttaagc ttttcatttg atatatattc tatgaaaaca ttttttataa taatttttag
    33541 ttatttattt aacatatttt aatttgaaat caaatcttat aaaagttatt ttttattttc
    33601 ttaccacaat tcaaattctt taaacattta ttatacccta tttttctgta cttaatcaca
    33661 tttttcaaaa tcaacttgtt ttactctatt taagtaaatt gtgatataat attgacattt
    33721 ttttaatata ttgatatcat ttaaacttag aaaaatttat ttttaaataa aaggagaaaa
    33781 atattggaaa gttcattttt atcacaattt cttatgatta cagattttaa aacaattttt
    33841 ttcataatat tacttctagg tacgttcttt attgttagac aatttgaaaa gaaaaaaata
    33901 aaattttcat tgagaacaat atatgctaca gtactaggac tcatattggg aatcataata
    33961 caagcttttg ctggttttcc taatgataca actcaagtca cttggctaca agaagtaagt
    34021 aagtggtata gcctatttgg ttctggattt atggacttat taaaaatgtt agtagtacct
    34081 ttagttttct tatccattat aaaagtaatt ataaatatga aagataacaa tcttggaact
    34141 ctgacattta aatctttagg tatgcttctt gctactactg ctatagctgc aattgttgga
    34201 attatcgttg caaatataat gaagttaggt gtaggagcta atatgcctac tttagttgaa
    34261 aatcaagaac ttaaagaaat aaactctctt gtggatactt taagaggatt actaccatct
    34321 aatcctgtaa tggctatggc aaatggaaat attgtagcta caataatatt tgctacattt
    34381 atagctacct caataaagag attaagtaaa aaacattttg agacaataaa accatttata
    34441 gattttatag aagcatctta caaaataatt gtaagtgtgt ctatgactgt tattaaattt
    34501 atgccttatg ctgtggttgc tctgcttgca aatacaataa cttcacaagg tattagttca
    34561 atagtatctg ttttacagtt tatagtagct ctttatatat cagttgcaat attatttatt
    34621 atacatttaa tttttataac tttaaatggt ctaaatccca ttacttatat aaaaaattca
    34681 actgaagctt tacttctggc atttacttca cgttctagtt taggaacatt gcctgtaacg
    34741 atagaaagtc tagtacaaaa tcacggagtt gatgagggtg tatcaagctt tacagcaagt
    34801 ttaggtgcaa atatgggtat gaatggttgt gcaggtatat atcctgcttt aatggctgta
    34861 acacttgcca atatggctgg agtaaacatg gatatgagct tttatgttat gttgttaatt
    34921 gttataacaa ttagttcatt tggaatagct gggcttccag gaactgctac aatggccgtt
    34981 tcagttgtta tctctggagt tggtcttggt tcttattttc cattagttgg tggtatactt
    35041 gcaatagacc ctatactaga tatgggacgt actatgataa atgttaatgg tgctatggta
    35101 tcatcaatta ctgtaggaaa atcacttgga aaaatagata aagaagtatt tagtaaaaaa
    35161 aatatttctt agaataacac tcaaaataaa tggctaactt tttaccagtt agccatttat
    35221 tttatcagaa aactttttta gaaatttact cacaaaacgg aaaaaattct tttgtaagat
    35281 tttggggata tacagatata aaaacaaagt catagtcatg ggattttgca tattctagta
    35341 tatctccatc ataatatcta gggtctatca tatctataga tgaacaaaca gaggaaaaaa
    35401 atgctgctgt tggtacaatt agagaatctt taacaaacag cacttttaat ccatctggat
    35461 tttctatatt ttttatttta actaatggtc tgttccccaa taaatatgta aaatacttat
    35521 ctgattgacc atccattaaa tcaaggtctg cattaaaagg atatgataat attaaactct
    35581 cttcaaacct tccttttaat tcaaattttt gagatttaga atctgtataa taagtataat
    35641 tagtcttaaa tttaggataa attaatgtaa aatcatctat accaccatat aagataccag
    35701 tctttcttcc catagaacca agaaatgact taggatatac aattgaatta taattgtcct
    35761 tatctctata ataatgattt tcatctaaat tcatattgta ttttttatta agttgctcaa
    35821 ctaattctcc aaatgcccaa aaagaagttt ctactttcca gtgatggtct gttttaaaaa
    35881 ataaatcatc ttttggaata ccactcttta aaatattttc tctaaaatca atatagtcca
    35941 cattatactt ttttagttga tttaaaaaat tatctgctgt ctcattacta taagaataag
    36001 gtattccttt tggaaattct gtcactcctt ttatatactt atctggagtc attaggtaaa
    36061 ccaatttagt gttttgcttt tccatttcat cagaaaattt tcttacccta tctgctatca
    36121 caccaactgg atttggagct ttagcaaaat atgtataatg catctttcca gaagtatctt
    36181 ttacaacact aaattttgaa aactcatttt tacccattaa tttttgtaaa tagccataag
    36241 tttcaatgaa cgtatttttg tatattactt tgtcattcac tgtattatca atagatgata
    36301 ttgtatcttt taaactactt ttttcagcta ttgaattttt tatttcctgt atcgtatctt
    36361 ttccagaata acaaacatta aagatagaga aagcgaataa aataattaag aacataattg
    36421 cagttattaa tcttacttta aaaaatctat tcatactttt cctcccaact aaaaattaaa
    36481 ataaataaat ggattatagc ttccagttac taaatatgtc acagaaataa aaaacaataa
    36541 aatagctgag attggataaa atacgttaaa tatcatacta tatttagctt gttcaacaac
    36601 aaacttattg attttctttg caataggtac actaaaaata aatgcaaata taaagaaaac
    36661 ccagtattct tttaaaaaca tatatgtata atcactccat atagctccat tgcctccaaa
    36721 catagcttta aaataattat atgcttcttt taaattaggt gacctaaata atacccaccc
    36781 aaaattaact actaataaag cataaatatg ttttataaaa ttgtgatttt caatcttttc
    36841 aaacattata aatcgctcta taattaggaa aacaaagttt aaaatccccc aaattacaaa
    36901 tgtccattct gctccatgcc atattccagt aaataaccac actataaaca tatttctaat
    36961 cataatatct ttatttgcta ctctagaacc tccaagcgga aagtatatat agctcttaaa
    37021 ccacattccc aaagaaatgt gccatcttct ccaaaactca ctaattgatt ttgatatata
    37081 tggataatta aagttctctt caaatttaaa accaaacata agacctaagc ctatagccat
    37141 atctgaataa gcagaaaaat caaagaatat ttgcagagta taggctattg aaccaagcca
    37201 tgcaagtgat gcagctattt ctccttgact attcatagtg taaatatagt ctgctactat
    37261 agccatgtta tttgaaatta atactttttt acctagacct gttataaacc tacaagtccc
    37321 aatagaaaat ttattccaag tttcttttct attgagaatt tgttctgcca cactctcata
    37381 tctaactata ggacctgcta ttaattgtgg gaaaaatgct atatacaatc ccacataaaa
    37441 agggttcttt tggacttctc catgtctacg atatacatct ataacataag acattccctg
    37501 aaatgtaaaa aatgaaattc ctatgggtaa aacaatacta ggtatagtca attcagtact
    37561 aataagttca ctaatatttc ttagcgcaaa agctagatat ttaaatataa ataaaacacc
    37621 tatattgtat gcacacatca aaactaaaaa aacttttact tttattttac tttccctata
    37681 tctatctacc agtaaaccaa atatatagtt cattattatg gaaactatca tgataacaac
    37741 aaattttggc tctccccaag cataaaaaaa taaactaaca gcaagcaata tcatgttctg
    37801 tatcgttcgg ttaaacctaa atacataata taaaaccaaa gttataggta aaaaataaaa
    37861 taaaaaaatt aaacttgaaa ataacacaat ctaacctcct ctctttactt agtttttgaa
    37921 cattttttcc aatataaata tattccaaag catattatta ctagagatac aaataaaatt
    37981 cgaacaaacg ttatgatgtt attcataaag tttatttttt tcatatcttg tactgttggt
    38041 gattgctcag gatatactaa tgtatatgga acaccatcct tatctttttt attaacactc
    38101 caagactcag ttaatgttat tttctttcca attttaaact tatcatcaac attaacttgt
    38161 aaaataattt gtccaggttt ggctttatta cttaatgtta atttaccttt ttgagatatg
    38221 cttacattat cttgttttcc cataagagag tacttaattt tagaatcact tttaagacct
    38281 aatacttcat actgacttat actttgaccc aatactggta tttgtacttc ttcatcgcca
    38341 attattttaa tattatttaa aaatcttaat ttctcttcag acaataaaga tatctttttt
    38401 ataataacaa tattatgttc ttcatcagat ggaataaacg taattcccca actaacaatg
    38461 tttgaaagca tatttgagtc cagcacaaca ttactttcct catttataag gctattaaag
    38521 ttcacataaa ttttgccttc aaattcacct ggtacttcta tgcatccttc ttttatttta
    38581 tctgaatata ttatattttt accttctaaa aatacttcac taccttcttt taatctaaat
    38641 tcaagcatat ttttactttg tatgcttaaa tttattctct gagaactttt atttttattt
    38701 tgaatttcaa tataaaaatt attatacatg ctccaatttt cttttatatt ttggtaaata
    38761 tataaataac gttccttatc gcttttagaa ctatccgttt ctatttttac acctgtatct
    38821 tcatatgtaa tcttagaatt taagtcagtc tctatctttt taaaggacaa atctaaaatt
    38881 ttatcacttg ttgctgaact tataaaagta gtatttataa aaaaaataaa caccaaaata
    38941 agatattttg tagaacaaaa aaacactttt aaagtcttca tttcatctct cctaaatata
    39001 ttccatgggt tcaaactcat ctatactttt ttccttcttt tcactaggct ttgaaacaag
    39061 aattgtctta ttttgtaata tccaatccat catttcatct cttaaaaaga aattttgcat
    39121 tatgctgtca atgttattta ctttatataa gatacctctt tcatcaattt taccctcaca
    39181 caaatcacat tctaacacaa tattttcatt aatttccaat gctatttctt taggataaat
    39241 acttttattc tcaaaattta ataatacata ttgataatta aaattcacta ttcttaattt
    39301 acctgtattt tttatatcca tctgaaaatt catattgatt cttggacttc ttcgtgataa
    39361 tgttctagtt ttttcaatac gttttttcac attaatttgc aaatcatcaa agaaacctag
    39421 ttgattagat attgtcattg gtaaagtagg tattctatcg tgaacaatac acatccaatt
    39481 atctatttca ctatcttcaa tatgtgtaat ataagctgca tatttccact ttgaatttac
    39541 ttccacaaca ttaacaatct ttgctttcat attggctata tacatttcat ttccagattt
    39601 ttctctaaac tctacctcaa actcttcttc tggtgaaata tattctggat tttctagcaa
    39661 aaatgcaaac ccattttctg atatatcaat tgtttttgaa gaaagaacat aagaattttg
    39721 ctttaactta aaatcaattt cagcaatata acgctcagac tttcttaact gctgtctccc
    39781 tgatataaat aatgtagcca taacaaggtt aaaaaggttt ccaatcaacc aaaataatac
    39841 aactgaatat gtcattgaac tcattttaaa tattgctaca aacattttta aaattcctat
    39901 gatagataag accatgtaaa taaaataagg tattccctgt aaaaacttat acattctatt
    39961 ttcttctaat ttactcttat ttgttactga aaatttattt ttagatattg caaacgtttc
    40021 aagtattact gctggcatta aagactgaaa cattatagtt tcatatatat tggtccatct
    40081 agtatttctt atattttgag aaaatatttt aagagataaa ctacttaaaa tatacattgg
    40141 caaccaaaat accaatactt gaagtaatgt acattttact acaatcacat taaacacgga
    40201 aaataaaata ggtgccatta tatatacaaa gcgttttata cttgcatacc aataagtaat
    40261 tgaagaaata taacttattt tctgccaaaa acctaaacct ctcctaaaca aaatatttag
    40321 acgtctacca gtttgtatac atccacgtgc ccatctttca cgttgcttaa taagactttt
    40381 taaatctgta ggagataaac ctgatgcatg tacttctgga atagcataac atctataccc
    40441 cttactttga attaagatac ctgttgcaaa atcttctgta atagaataag tataaaatcc
    40501 atcaacttct tcaagtgctt cccttgaaat aactgtatta ctaccaccat aaattacaga
    40561 atttgtccta tttctagcca attgaatatc tctgtaaaaa taatcttgct catttggaat
    40621 ccttccttca gagtgcagat taaattggaa caaatctgga ttataaaaac tctgtggagt
    40681 ttgcacaaaa ccaacctttt catactcctc tttttctcca tcttttttag cttgctcatt
    40741 tttcaaaaag tatggtactg tagcaattaa aaagtcatgc attggtatca tatctgcatc
    40801 aaatgtagca atcaaagggg aatttgtatg ttgcattgca ttatttaaat ttccagcttt
    40861 tgctccttct ctttcagttc tagttatgta atttacaccc attttttctg ctagaatacg
    40921 catttcttta cgatttccat catcacatat gtatatatgt acctttttct tatctggata
    40981 ctgcatatga atacatccat ttacagtttt tctaaccaaa tcaacagatt cattatatgt
    41041 tgcaataaat acatctacat gtggataaag ttcttcactt atgattggtt tttcaggata
    41101 ctcaatattt gacataccat aataatgcac aaacatttcc atcataccca ttgtctctac
    41161 aaaaagaagt attatggcac atattaaggc aaacttccct tcttctttag gtactgtgta
    41221 aaaaattctc cacaatatat atatgacatt agtaataata gttaaagtta taagtatctt
    41281 ttttgaattt ttcttcataa aatcacctct tttctattaa tgcacttaat atatctctat
    41341 cccaagtccc ttcaatttga ttgtatatcc caaatccaga tgcaagctcc caataagccc
    41401 atgaaaagtt tcgtttttca gcttcttctc ttacagcttt tacccaagct ctccttgaag
    41461 tttctggtgc ctcttttgtt attccaaatt cacccaagaa gatttttacc ttatttttat
    41521 ttgcccaatt ttccacagta tcaaaccttt tttttaaata atccatttgt tcatttgttc
    41581 cttcccaagt aatattgctt aagtgctcaa atcccttatg atagatattt ccttgaaatg
    41641 caaaatcatt tggctcgtaa tagtgaaaag aaactactat attagaatct ttaggaatat
    41701 ttaattcatt caaataatca atttgataga aattatatgg tcctactata atagttcttt
    41761 ttgggttagt ttttctaatt atctttattg cttcttcaat gtattcgttt agtaattgtg
    41821 aagataaatt ttctttaggt tcatttaata attcaaatac caatttttta tcatattttt
    41881 gatacctatt agctatctgt tgccatattt ttaaaaactt ttctttatga actcttggtt
    41941 ctttcataat ttcttcaaaa tggtgtaaat ccaacacaac tattaattct ttatccaatg
    42001 cataatctac atatttatca atctttttaa aaaattcttc atcaatttta aaattatcag
    42061 aatctgacgt ataatcagaa aaccttactg gtatacgtac tgtgtcaaaa cctgcatctt
    42121 ttatatcatc aaaaaactta tttgacattt ttacatccca cggaaaatcc ttaggtgatt
    42181 ctagtgcatt acctatattt atccctcgtt gcatcttaac tgtatcactg ttatctctta
    42241 ttacaagata aaatccaata aaagctatac ttaaaaaaaa cattatgata atacctattc
    42301 tttttatatt aatcccccca aacaatgtta tcttccatat aatattattc aatccctatt
    42361 atagcaaatt aaagtacatc atgttacata taattattgt catttataaa ctttatagcg
    42421 tttatagtta gttttaaaac attgaataca actaaaaaac taaagggctg tcttagaata
    42481 gaaataatcc tatttttcat tgttgaaaca atgaaactat attgatttca tacaaaaaga
    42541 gtgcctcatg aactaaaaag ttcattttga gacactctta tattttttat actctgtcta
    42601 acaactctaa tacatatttt ttaactttat catatcccca attatcaagt gaatatccta
    42661 gttctatgtc accaaaacct ttaatttcag cattttcttt tttatttaat aattcttgca
    42721 taagctcaac ttctatatac tctcttccct tttctttttc taacattgta aataactcaa
    42781 agtcctgtat tccaaatctt aaattctcca ttctaacact tctaactggc tttaaatctt
    42841 ttccaggata aacaaagaac atatctccag ctttccaaat agggaatttg taacttgaat
    42901 ctttccaagg gtcttctgtc cataaattat agtcccatct taaaaatcca tcaagaccaa
    42961 agtaataagt ataccatcct attattctat tttctacaaa aggagaactt aaaaaactat
    43021 ttggtttctc tggaaaacag catacaaacc aagtcaatat cccacccttg tcattgattt
    43081 ttttcttaag actttctata tctttataat tttgtatagt aagttttaaa tttattgaca
    43141 tatcatcaat ttcatcttta gctctgtcta aaaagttttg gtcgtgagtt gctgatttat
    43201 atttaacttg atgagtatct acagtagaat ttataaattc tatacactct ttgactactt
    43261 ctggattatt tggttcatca gctataatcc ttactctgtc ccataatcca cactctatta
    43321 aatgatttaa tactaatcct atatattctt ttaaatcatt tgtattgttt ataaatttaa
    43381 atactttatc cttttcatca aaatatctta ctcttatagg gtccttataa ccttctacag
    43441 gatttccaaa ctcaccagca caccaattac ctaatagacc aaataaatct atctccttag
    43501 ccattttata cttatcagct atgcttatat acctatccat actctcaaag ttacatttaa
    43561 tctttccatc caatcctttt gatacactta ccatgttata ttcatataag tttgatggat
    43621 ttttataaac tttataacaa ctttgccctg cccatggata atctgaaact ataactgttg
    43681 caactttttc tcctaaagat gctaattctt ttaaatagtt atcgactatt tcaaaatgta
    43741 tatcagacca taactcaact ttatacattc tagctaaaca gcttggatgt tgccataaat
    43801 ctaaaaagaa cttgctttca tctaaaggct ttagcacaac atttcttact tttacaggaa
    43861 catcaattgt acaaactttt tcttcgtctt catatccaaa gcttttaaat atatcaatac
    43921 ctatatcaag gttattttct tcaaaatctt ctggtacttg accttcaatc caaaatgttt
    43981 gaggcaaata ttgctctact aacacatctt tatcccttaa aatagcatca ttcacaaatg
    44041 cctttgtatc atcttgaaca tatcctaata tatttatact aaaattattt tctaaactat
    44101 taggcatatt taatgctaac cttactctat ttcccaggcc tttccatgat atagcactac
    44161 ttttatcaat tgtacaatta aattcttctg ttgcttttaa cataatttga aatgcaaatt
    44221 tttcaccttt agctactaca atatccaaat ccttatcttt ccaagtttca gcttctacaa
    44281 ctgagtattt attgtgtttg aatgtgcaat ctttcagtac atatgaaatt tccatagttt
    44341 aaattcctcc atatttatat aagtttcttt atatattatt aaattagact atttaacctt
    44401 ttataccaga caaagacaca ccttcaacaa atttactctg taaaatcaaa tagaaaataa
    44461 atggaggtaa aaatgttatt gtagcccctg ccatcatctg tccataatta gttatctgga
    44521 atgtcttaag agtagataat ccaactgtta atgttctcat tgcatcttta gttgtagcta
    44581 taagaggcca cataaactcg ttccatgctc ccataaaagt aaatattgct agtgtaatta
    44641 atgctggttt aattaaaggc aacactattt gtattaaaat tctaaaatcc gaacaaccat
    44701 ctatctttgc tgattctaat aactcttttg gtactcctaa aatagcttgt ctcattataa
    44761 atacgccaaa tgcagttggt attggcataa taagtgcaag ataactattt atccatccta
    44821 agtgtttcat tattatatat agtggtatca ttgtaacttg ggaaggtata attaaagtca
    44881 ttatcataaa taaaaataac ttatcactac ctttaaaatc catcttcgca aaagaatatc
    44941 ctgctaatgt actaaatact aaatttaata atacacctga aaaagatact attgctgtat
    45001 taaaaaaata ttgtgcaaat ccttttttag taaaaatatc tatatagttt tgaagggtta
    45061 ctgttgaaaa agatatatcc aaactatatg agttatatgt tatcttcaat gatattatca
    45121 acatgtatat aaaaggtacc aaacttgcac acgctataaa taaaagtaaa ccatcactta
    45181 ataatcttct tgctgttttc atattatacc tacctttcta aaaatctgaa ttgtctcgtc
    45241 ttacaagctt attttgtaaa atcgaaacta ctgctattaa caaaaataat acgtttgcta
    45301 cagtcattgc atatccagaa ttaaagtttt taaagtttaa gttaaatgca tgcataacta
    45361 tactcatagt agatatacct ggacctccac ctgtcacagt ataaattaag tcaaatactt
    45421 gtaatgacca tatcgaccct aaaaatacaa ccattattgt agttggtttt aataaaggta
    45481 cagttatttt tataaattct tgaagttttg tagccccatc aaccttcgct acttcatagc
    45541 agtgttttgg taaattcatt atagctgaaa tataaattac catgaaatac cctatatttt
    45601 tccacataga tataaacata agtgtaggta atgctgtctt actatctcct aaaagtttag
    45661 atgattctat tccaaaggca cctaatacct gatatataat agaaccttct ccattcaata
    45721 aagccctcca taccatacct atcaaaacca tagatgataa tactggtata aatatagcac
    45781 ctttagcaaa tgaagctatt ttactatttc cttttcctgt aatccaaaca gccaaaatca
    45841 atgataatat agtttggcaa ggtactacaa caacagtaaa tttaatagta tttataatag
    45901 atacttttaa tgtttcatct gtaaataatt ttttataatt ttctaaacct ataaaagtag
    45961 ctggactaat aatattatac tttgtaaaac taaagtatat tgacattatt attggtatca
    46021 cataaaacgc cactaaaatt attcccaatg gcaatatata catatatggt ttaatattta
    46081 attttgtttt ttttcttttt gaattttctt caaactctct aactaagttt tccattttat
    46141 cctctccaat ataaatatta gcattgtatt tataaataca atgctaattt taatctgtaa
    46201 agtcctttac aacatattac agctttaaac ttttattgtg ctaataaatc atttgaatat
    46261 tttgcagcat catctaacgc ttgttttgga gttttatctc ctgaaatcat agtttgaagt
    46321 tctttccata aatattcata tatttcaact ccatgaggtc ctactactaa tggtctatat
    46381 acatttttgt cattttccac catttctttg aatctttcat caccttgata tggttcacct
    46441 tttgttattg gtgctcttgg tattgcttta tgaaattctg tcattgattc aacacttaac
    46501 atatgttgta ttaacttgta tgcaagttct ttatttttcg cagatgacat taaagataaa
    46561 tggtctactg ctccaaaagt tgctgctttc ttatcttcta gtccagttac aaatccccaa
    46621 tttaaatccg ggaatgattc atcaaataca cttgttgcag cagaagataa cattattgta
    46681 aatgctgctt tccctggtcc aaatacactt tctatcattt cattactatc tttagataaa
    46741 gaatcttcag gcacatatgc ttgtaattct tttaagaact tagctgcttc taaaccactc
    46801 ttatcattaa atttaaccga ttttaaatca tcattaaata tatctccacc agcttgccat
    46861 aaataaggat accagttcca gtttaagtta ccaaaagttt tagctcccca tccctgagct
    46921 aatccccatt ggtctatctt tccatcacca tcagtatctt gcgttgcttt tttacaaatt
    46981 cttttaaaat cttcccatgt tttaggaggt ttttctccta gtttctctaa aatatccttg
    47041 ttatagtata atacccctgg atttgctgct tggaatggca taccatacat tccacccatc
    47101 atttcagatg tttttatata aatagattgc tctttatcct ctttagttgc atagttagtc
    47161 aaatcttcta ctgctccact ttctataaac tgtggataca tttctgcata catatatcct
    47221 acatctggac cttcgccagc acttatagct gttgcaaatt tttcagaata attatcccaa
    47281 ggaattatct gtaaatctac ttcacagtta tttttttcct caaatttatc taaaataggg
    47341 tcccaaactt ccttcatatt attttctact ggtggcatcc aaagaactag tttttctttt
    47401 tcgccatcct tttttgaatc ttttccattt ccacttgaac accctgttat aagtgttgta
    47461 gtcataattg ctaccatagc tagtgaacat aattttttta acatacccac ttttattccc
    47521 tccattttat tttctttttt catttttatt ttcttttttc attataattc tacacatttt
    47581 cactccattt aaaatattat caaagcatgt atttattgtc taatcagttt tttctatgta
    47641 ctttttttta atatagtttt tttctatgac aacgtttcta atatttataa ttgatacctt
    47701 ccaatttatt ttctccaatt taaaatttaa ttacgcatct ttttaatcta caataataaa
    47761 aagctgtaga tttttaccta cagcttttaa atgatagcat ttattatata ttattaatat
    47821 tctttgttga taaacttcaa agttcattaa catatttttt taaccttaat attcataatg
    47881 aattacactt ttatattcat caaaaatctt cttatttaac tcatctccac catcaatatt
    47941 ggcactatag aaaatcggag gattctttag ccctttatta actaattcct gagtagcttg
    48001 agctataata gagttcatca cagtagttgc tattacagta gaagttggac taactttttg
    48061 gtttaatcca tctatctcta cacaggcatc tcccttttga ccatgattat ctatcactaa
    48121 atcgcatact tcataaagtt tttttcctga agaatgtctt gaagatacac tttttgagta
    48181 acttaaatta gttatacata ttactattgc cttattttcc ttagctttca tagcaaactc
    48241 tatacttact ggatttctac cagatactga atgaactata actacatctc cttttttaat
    48301 tggagtttta tcagctagag ctgtaccata tccttctaat ctttccatct tacttgtgtg
    48361 agttataggc gctgtatcta acattagaga ttttgcaaat actggattta taagaacaca
    48421 gccacctgct ctatagaata attcttctgt taatattcct gcatgtgaag ctccaaatga
    48481 aaatatagca tttttacttt ctattgcttc aacaaagatt tgtactgctt tttccatatt
    48541 gactttttct tcgttttcta ttatatcaat taatcttctt atctcatcta tgtatttaaa
    48601 tttcatatct ataatattcc tccaaatagt gaacctataa acttactaat tataccaaat
    48661 aatgaaaggt cattacctcc aaatattagt atccaatttt gaatagttcc tgagtaaatt
    48721 acagcagata ttcctactaa aactaccata aatattgcag ctatagctgt acctattata
    48781 gctccacgta taccaccttg tgattctcct attactgctg ctgctccaca ctcaaagaat
    48841 gaagttataa caagtggtat aagtagcaaa ttaaatacat taaagtagtt acatattaaa
    48901 atcatagctg tagatgttag catagcaact aagaatccta ttaatacagc atttggttta
    48961 taattaaata atattggaca gtcaaaagca ggtagtgcat ttggcacaac tttttcagat
    49021 ataccttgaa atgctggcat tatttgattt attagcattc ttaccccata aagcattatt
    49081 ataagacctg ctccaaaaga aagaccttgc tttattgcat acgttccaat aaactcatta
    49141 ctatctttaa acgcacctgg tattactatc ccaacaacta taaacattaa aaacactgcc
    49201 attccaccac ttatagatat ttctctaaaa aatgataaac tttgaggtat gtttatatct
    49261 tctgtagatt tttctttatt tcctactaat ttagcaacaa atcctgatat aagtgctaaa
    49321 caaccagatg gatgacctaa tgtaaaagaa tcatctccta taacatcaaa cacatatttt
    49381 cttaataacc aaggcattat tgaccaatag agtgctgata atactgctgc aaaagctatt
    49441 aatactccac catttaatcc agcttcaact cctgaagcta caaatatgaa tgggaaccaa
    49501 taaagcatgt gacctgttaa gaagattgtc ttaataggag taaatcttgc tatcattagg
    49561 tgaatagcta aacccgcaaa cattgctaaa cctataattc caccataact tgcagtaaaa
    49621 gtaacatcac ttaaaccttt tgttactgca ccaccactta tactttggaa agctccatta
    49681 attggtgcta ttgaactaac taacatacct gttccagtct ccataattat aattccgaaa
    49741 gctgcaagta gtgacccctt tataacatca gatgctttct tcttctgtag tacaagacca
    49801 aatgctgcta ttaatccaat taacatagat ggattacgta aaatattatt tgagataaaa
    49861 tcaagcatta tattttttag tgataggtca actgtttaag ttttctacca ctaaatccct
    49921 cctctctttc ttactatttt tgaacttagt aagtttttat tttattctga ttaacttaaa
    49981 tttacttttt aaaacttata ctatttctta tcatttttat cacttaaaaa agtttgaaca
    50041 acttctgtga cttctgctaa atccatgtac tttttaactg gatatacatc tacattacaa
    50101 gttcctttta attcatttaa caattcttga cttgtgaata tacagtcaca atcagcacct
    50161 ctagctgaat ttatatctgt attttctact tcacattcta tacctaactg ctttagagcc
    50221 ttttggattg tcatttttaa taccattgat gaacctacac caaaaccaca tactgctaat
    50281 atcttcattt ttcattcccc ctaattttgc ttatttataa gttctattat tgaactttta
    50341 tcaccattaa ttattagttt tacattttct tcctcgtaca tcatctctga tagtgatgct
    50401 aatgctctaa tgtgagtagt gttatctaca gcagctaata ccataaatat atttactggt
    50461 tttcctaata aatcaacttc atcttctact attagtaaag acatagcaag cttgtttact
    50521 ccttctttag aacttgcatg tggtagagca aatctatcag ctaaaacaat atatggtcca
    50581 tatttctcaa ctgactttat catattttct atatataact cttctataga gttatcttct
    50641 aacaatggct ttgaggctat ttttattgct tctttccaat ctctaacact ttttattata
    50701 ttgacccttt ctgcattaat taattccttt aacattggtt gatacatctc tccttcatct
    50761 atcttgtgta ttatgtttaa taaatcagct tttagtgctt cttcattatt gataactcca
    50821 ttttttctta tagcttgtat tattaattca agattgaaat acttctcgtt ttcttttaca
    50881 cttattagtt tgttcataag taattgaaca tctgatgatg ttaaaagagg atttacaaca
    50941 attacgttgt ttacattttg tatatctata gttgtaatta tgtaatcgta gtatacattt
    51001 acttctttta gttgcttaat ggatactata cctactattt ctatggttgg tatgtattta
    51061 tatagttgta tttccaaact ctttgatacc ataagaccat taggacaaac tagtaagact
    51121 ttatttcttc ttagaccatt atccctagac cctcttaaat atcctccaaa atacgctgct
    51181 ataaatccta tttcttcttc tcttatcccc tcaaatacag gaaactcttc ttcattttct
    51241 ataattgatt ttataatttt ataaagtgac tcatgtttat acttagtctc atctaacatt
    51301 ggatttctaa taggaaactt aaatcgtatt ctgttgtaag aagaatggag gtgccttaaa
    51361 atatttttct taaactcatg cttactttct aattttattg ctgtatttac ttcaaactta
    51421 tctataagtt tatctacata ttcttcaaca acatcttcct taacttcact atttaagctg
    51481 ggaagtgaac ttatgtaagt gcatatatag gcttgttcat tttcattagc ttcttcacat
    51541 aaaagttctt tacaattact aaagtaacta atttttttag cttcatttag atatttatat
    51601 gagtataatg ttttcccatc tcttatcctt ttatttagaa attccacaaa cttagttaga
    51661 tttaataaag aataatcagt aagttttata tgtccttttg tatcgaaact acttacttcc
    51721 tcacttatag aattaatttc cagtacattt tcttgaacaa ttatcagaaa cagctctcta
    51781 ataacgtatt catcacctat aattttgtac tttcccttat actctaatct taaccccatt
    51841 gtttgaaggt atttttttac atcagttatt gtttgtacta ctgtgttttt tgaaagtaac
    51901 atttcatttg ttagtttttc tattgatatt ttttcgccaa gtaatatctt gtttaatata
    51961 aaagtttttc tgtagtcact atctaaaaat ttatcttctt cagttgaaat tattttcctt
    52021 gcatcacata aattaccttc aaatataaat ttgtgtttta cattttttat attaccactt
    52081 tttcctagtt gtttatttat agctagaata tcgtaataaa tagttctctt tgaaacatta
    52141 aacttttctt gtagttcttg tgatgttaca ttgttatttt taataataaa atctaatatt
    52201 tttttagccc tttccttcat actacctcct taattttatt atctatattt tctacatgta
    52261 gtgccatacc aaataattgc acatgattta gtattatttt ataattttgc acagtctaac
    52321 tctaatctaa aagaagacag tggtaaaatt attaaaaaaa tttgaaaata acctatatta
    52381 tttatacaaa taaataagtt gatttcaaca aataaaagat taaactacat tataatatca
    52441 aaataagata taagtaatct aaaaagcaca attatataac aaaaaattgc tatattaaaa
    52501 gagagctatc acacataaat tggaattttt tgtgtaatag ctccattttt atttatttaa
    52561 aatttatttt ttaggtctaa gttcagcttt atctcttttt acttcttcta atatttctct
    52621 taaattatac tcaacactag aaagcacatc ctctgcatat tcaattgacc caattcttat
    52681 ctcattggct attctctcag ctctatcaac tatatctttt gctctttggt ctgcttgaac
    52741 aacaggttca ctggattcta catatgcctt tactacatct tcagaatttt tctttaattc
    52801 ctctatatta tcttgatatt cttgttgtat tctctcagct tcttttttcg cttgttcaac
    52861 tatatttgta gcatcttgct tagcttgact tattatttta tttctttctt tattaatcca
    52921 tactgcctgt gttacttctt ctggtattaa agttcttata tcattaatta ttgctaaaac
    52981 ctcatcttta tccactgtgc atttatgtga gaaagggatt gtagaagcac ttctaaatat
    53041 ctcctctaac tgctcaaata gttcaatcat ttctaaatct atcttcatat atcaattacc
    53101 cccactagtt tttttcttta attcttccaa aacaatcttt ggaaccaaat tttttatatc
    53161 agcatcaaag agcaaaacct cttttattaa agatgaactt ataaatgaat attttgtaca
    53221 acttggtaaa attatagtct ctatatctgg attaagctct ctattcatat gcgccatctg
    53281 aagttcataa tcaacatcag caccacttct cacacctcta actaatgctc caatcccatt
    53341 ttcctgacag taatttatta ataaaccatc aaaagtcaca acttttatat tatttaaatg
    53401 gcttgtactt ttttctataa gttttactct ttcatcaaag ctaaatagac cctttttatt
    53461 aggattattt aatactccta tttgtaattc gtcaaataac ttcgaagccc tgcaaataat
    53521 atctaaatgt ccattagtaa ttgggtcaaa acttcctgca aatatagctt ttctaggttt
    53581 attttccata ttatgcctcc atcttataaa aagttaatgt agtatttcca tatttcttat
    53641 ctctagtttt ctccaattta catatcttat ctggaaataa atcattcgta tcatgttcta
    53701 caactattat tccatcttcg ttcaatagat tagaattatc aattttttca atagcttcta
    53761 taaacatatt tttataatac ggagggtcca taaaaattat gtcaaattta ctattttgta
    53821 atttaagttt atctattgca gtcttaaaat caaggtttaa aataatactt tcactttcaa
    53881 ctcttgcctt ttttatattg gacttaacaa tatctatgct ttccttactg atatctacaa
    53941 aagtacatga cttggcaccc ctagataaac actctattcc taaagaacca gtcccagcaa
    54001 ataaatccag aacttcactt tccattatat atgaatttat catattaaat agagactctt
    54061 ttactctatc tgtagttggc cttacatctt cattttttgg agtatttagt tttaatcctc
    54121 tcgcttttcc tgaaattact ctcaatatga caatctccct tcagcacatt attacattag
    54181 taatatttta acacaattta aaattaattt aatgaaattt ctttcaatgt atctttaaat
    54241 ttatctataa tttctttttt gagtgccatg ttttctttta attgtagatt attatcttca
    54301 cccaatatat atcgagcttc ttgctgtgct aacttcagta tttttatatg tttaaataag
    54361 tttgctacct taagttctgg aagaccatgt tgccttgtcc caaaaaattc cccaggtcct
    54421 cttatttcta aatccttctc tgaaatctta aaaccatcat tggtctcttc cattatagcc
    54481 attctttgtc tacatacatc tgttttagaa tcataaatta gtacacaata cgatttatga
    54541 ctacctcttc caactcgccc tctaagctga tgtaattgtg caagtccaaa tctttctgca
    54601 ttttctatta tcattagtgt tgcatttggc acattgacac caacttctat tactgttgtt
    54661 gaaactaaaa tatctatttc tttattttta aaaagtctca ttacttcatc tttttcactt
    54721 gacttcattt taccatgaag caacccaagc cttaagtcgt gaaaatattc tgctcttaac
    54781 tcctcaacaa gttcaactgc tgatttggct tctatggctt cactttcttc taccaaggga
    54841 catacaatgt acacttgtct tcctgattca acctctcttc ttacaagatt attatatgct
    54901 ctatctcgct tacttttttc aatagcaatt gtttctattg gctgtcttcc tggaggaagt
    54961 tcatctataa tagaaatatc taaatctcca tagagtataa gtgctaaagt tcttggtatt
    55021 ggtgttgctg tcattactaa tatatcagga tttgctcctt tcaatgaaag tttgctcctt
    55081 tgcataacac caaatctatg ttgttcatct gttataacta aaccaatatt attaaattca
    55141 accttatctt caattagtgc atgtgtacct attaatatat caatctcatt attctttatt
    55201 tgttccaata ctgtatcctt ttgttttttt gtaagactac ctattaatag acctacattt
    55261 attccaaaat cttttagaga ctcagtaagt gaaatataat gttgccctgc taatatctct
    55321 gtaggtgcca tcaaagcgcc ctgataacca tttaaaacac aatttgcaag tgctaagaga
    55381 gctactactg ttttaccact ccctacatca ccttgtacca atctattcat tattttctct
    55441 aaattcatat cttgtataat ttcatctaat gccctgtttt gagctttagt cagtttaaat
    55501 ggtaaagcac ttattatttt ttttaagtct ttacttgttt caaactttat tccatcttct
    55561 ttatttctgc cacttttaaa tacaaacaac cctagttgta gtataagtaa ttcttcaaat
    55621 acaattctat ataaagctat ttttaatgat tccttactac ttggtgaatg tatgtttcta
    55681 actgcaaaat ctatactaca tagcctatat ttttctataa ttctttgtgg catatattct
    55741 tgtataatta attctttatc ttcaagtact gttctaatta tactcataat ttctttattt
    55801 gtaacaccgt atgtaagctg gtacacaggc ataaatctac atgtattctt aggtgaatta
    55861 gtaagatatt ctaattcaca tgatgtaagt tctaagttat taaatttttt cttaaccttc
    55921 ccaaaaacta atattgaatc tcctggacga aaagtatttt ttatataact cttattaaaa
    55981 aacactaatt tagccgagcc tgtctcatct tttacatcaa tctttgttaa agtcatacct
    56041 tcttttgggc taaatgtatt tatacttgat attactgctt ttatcgtaac tttctcacca
    56101 tcttctaatt gtgctatttt ctttagatta tttctatctt caaattgtct tggaaaataa
    56161 tacaataggt cttttagtgt aaatataccc agtttattta atttatctgc ttttttaggt
    56221 cctattccct taacatattg aacatcttta tataaatcca acaaatatat cacctactac
    56281 acaaaaatcc tgtacaacca attttataaa agctacttgg tcatacaggt tcttataatc
    56341 attattcaac tgaaattaag taataataaa gaggttgtcc tccataatat aactctacat
    56401 ctacatcttc aaacttttct tctaaagaag tacgtagttc atttgcttga gattctgtaa
    56461 catcttcacc aaagaataat gttattatag cagtatcttc atcaaccaac ttttcaataa
    56521 ggtttgatgt tacttcatcc acataatctc ctgctgataa taaattccct tctgcaattc
    56581 caattatatt accttcttta acatcaattt cgttcatcac tgtatcccta acagcaaaag
    56641 ttacttgacc tgatttaact gagtttaaag cattcatcat agcttcttta ttttcatctt
    56701 cgcttaattc tccattaaaa gttactaatg cagcaaatcc ttgaggcgta ttttttgtag
    56761 gtataactat tatattttta tcactcaatt cttttgcctg attagcagcc attattatat
    56821 tgctgttatt tgggaaaata aatatatttt tagcatttat atgctttata gcattcataa
    56881 aatcttcagt acttggattc atagtttgac caccttctat tatatggtca actccgaaat
    56941 ctttaaatat atttgccaaa ccttcaccca tagaagtagc tataaaccca aactcttttt
    57001 cttcttctaa aggttcacta tcattttctt tcttttcttc tacatccagt aatgtatttt
    57061 catgttgtaa cttcatattt tctattttta tagttaataa ttgaccgtac tttagagctt
    57121 cttgaagtac atttcctggg tcattagtgt gtacatgtac ctttatgact ccatcatctc
    57181 caactactgc taggctatca ccataagcca tcattatgtc tcttatttta gtatcttcta
    57241 ccttagaact ttctaaaata aattctgtac aatagcaata ttttatatca tctgtgctag
    57301 tagtactctt tgcaaaatcc atacttgttg aaatattagt atctaggtca acatttttta
    57361 tttctatgtt atcgcctttt atagaagcta acattccttc atatataagt acaagaccct
    57421 ttccaccaga gtcaaccaca ccagcttctt ttagattctt tagaaggtct ggagttcttt
    57481 ctaatgaaga atttgattcc ttcacaagca tacttaaaaa ctttactaca tctttctctt
    57541 ttttcgcagt ttttattgca aactctccac tttctctaac tacagtaagt atagttcctt
    57601 caattggttt tattacagct ttatatgctg tgtctgaacc atttttaaaa gcttttgcta
    57661 aatcttctgt tgataattta ctttttcctt ctatagattt agctatacct ctgattattt
    57721 gtgaaagtat aactcctgag tttcctctag ctcccattaa agaaccttta gataatgctt
    57781 ttccgatatc tgatatatta tcattttcaa cttttgctaa ttcttttaag gcataagata
    57841 ttgttaatga catattagtt cctgtatctc catctggtac agggaataca tttaacttgt
    57901 caactaactc tttattgttt tggagattgt ttgcacctga aataaacatc tcccttaacc
    57961 ttttaccatc tatatattga atcatttgtt tcctcctatg aaattactta actcttattc
    58021 cttgtacatt aatatcaatt ctagtaactc ttacgccagt cattttttca actacatatt
    58081 ttactctatc tattatatta ttggcaacag tagatatatt tgtaccatat tgtattataa
    58141 cataaagttc gattgctatg gcatcttctt ctacttcctc aactcttaca cctttagttg
    58201 cgttctcgcc ttttaatagc tctactattc ctttagactt atatgctaaa cctactaagc
    58261 cataactttc cattgcagct ctatatacga cttgagctat tacttgatta tctatttcta
    58321 tatttccata ttgattcgtt acctttgcac tcatggttga cccccttaag cttattttta
    58381 ttaaaaacat ttcttaattt attttttact atttttactt atttattata taaaattata
    58441 atcatatcat actataaata tggtataatt taaacctaga aaagtttttg gataaaattt
    58501 cttctatagt atatatattc aaagaaaaat aataattatt ttcc
//
LOCUS       DAEORM030000021        56637 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.021, whole genome shotgun sequence.
ACCESSION   DAEORM030000021 DAEORM030000000
VERSION     DAEORM030000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 56637)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56637)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 56637)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56637
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.021"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            180..368
                     /gene="srl"
                     /locus_tag="KRH23_001740"
     CDS             180..368
                     /gene="srl"
                     /locus_tag="KRH23_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virulence factor Srl"
                     /protein_id="HHS5225020.1"
                     /translation="MNKIATKSRAEYMKNRRKDKRGFSVLLDKEKLDKFDEVLEEKNL
                     TKKEWLEEKIDEELEQKE"
     gene            489..854
                     /locus_tag="KRH23_001741"
     CDS             489..854
                     /locus_tag="KRH23_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BRO-N domain-containing protein"
                     /protein_id="HHS5225021.1"
                     /translation="MKNELMMFEGKEIEVFEFEGRILFNSKDVANCLDIKNVNENIRL
                     MNEKQVVKLRNSDISNTDIRKLNNAGENFLTESGVYKLIFKSRKEEAERFQGWISDEV
                     LPSIRQTGAYINNNAIPKS"
     gene            851..1303
                     /locus_tag="KRH23_001742"
     CDS             851..1303
                     /locus_tag="KRH23_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5225022.1"
                     /translation="MREKASEIEKLQLVYNSTSMLKELLDDAGFDNKSKLLTAKTLYK
                     KAEIDLPIEINEEEHYFDTKQIASKLKIYSKSNKPAQMAVCEIIKKIDLEDGEVKGVW
                     ETNGSWTGTVNKYTKSVIDKVRTWIEENNRPTKIAGEKKNYHVFYKIE"
     gene            1355..1516
                     /locus_tag="KRH23_001743"
     CDS             1355..1516
                     /locus_tag="KRH23_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5225023.1"
                     /translation="MCENLLDNMYIEKRKEEYRIKLLKIRETDIDIYNKLESIVYKLS
                     EKKLEKNNK"
     gene            complement(1845..2195)
                     /locus_tag="KRH23_001744"
     CDS             complement(1845..2195)
                     /locus_tag="KRH23_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5225024.1"
                     /translation="MDSIKSIQDIEIEQSRLKGQLQKNSNPIFALYISIMAVVFSTTI
                     NLTFDLSDITNYFIRMIMTLLFIVLLIFLVNKGILPIAIPYKNNIQFYTTALDVLEDM
                     KKKILRERKYKKRR"
     gene            complement(2445..2762)
                     /locus_tag="KRH23_001745"
     CDS             complement(2445..2762)
                     /locus_tag="KRH23_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5225025.1"
                     /translation="MDFGNINLILIGIIVIIGTTIIYLIKPKTAFCSKKYFNKLESIY
                     GNIDKKKTVKLEVLYRYVTGLEYIAIGLFTRRLDITILAIILVAIITTALYYLIRKKY
                     ITI"
     gene            complement(3140..3340)
                     /locus_tag="KRH23_001746"
     CDS             complement(3140..3340)
                     /locus_tag="KRH23_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5225026.1"
                     /translation="MYFKTYILKREVNNKQLEITRSFDLDNLICTATEILEDIEIDLI
                     IIDEKNNVVWRNEKSTPAHENA"
     gene            complement(3359..3772)
                     /locus_tag="KRH23_001747"
     CDS             complement(3359..3772)
                     /locus_tag="KRH23_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5225027.1"
                     /translation="MKVKSKRSFIVGIIVCMLCCASLVIYCILKDKRFLISSFLLIVI
                     AIFNFCNAFSRKSIVEELHDSTDERDLYLTMKTSHILVKIMNYTLFTFTFLFIIAYSA
                     CKNQSLLVIAITLCVIEIFLFVAYLLINIFLEKKE"
     gene            complement(3756..3989)
                     /locus_tag="KRH23_001748"
     CDS             complement(3756..3989)
                     /locus_tag="KRH23_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HHS5225028.1"
                     /translation="MKTKVREFRTNMGLTQQQLADLVHVSNRTIISIEKEQYSPSLML
                     AYRMAQVFGTTIEELCCLKENKEMEDKKHESKE"
     gene            4208..4546
                     /locus_tag="KRH23_001749"
     CDS             4208..4546
                     /locus_tag="KRH23_001749"
                     /inference="COORDINATES: protein motif:HMM:NF015898.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HHS5225029.1"
                     /translation="MKISKLPEVELKVMRYICEANKVLTSRELVAAMEEKYEWNESTT
                     FTVLKRLERREFLSTEKIGKLTHYNILVKEKKYLRFETKEFLKNIHKNSISSLMSALH
                     GKTTKWMKIN"
     gene            5193..5885
                     /locus_tag="KRH23_001750"
     CDS             5193..5885
                     /locus_tag="KRH23_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HHS5225030.1"
                     /translation="MYNILVVDDDKEIVDSIEIYLKSEGFKIYKAYDGMKALEIITEN
                     DIHLILMDIMMPKLDGIKATVKIREERNIPIILISAKSEDTDKIIGLNIGADDYITKP
                     FNLLELIARVKSNLRRYVTLGNYEDTCKEILKSGALELNTLTKEVKIDGENIKMTPIE
                     YKIIELLLENKGRVFSIDEIYEKVWNEESFNSENTVAVHIRRIREKIEINPKEPRFLK
                     VVWGVGYKIEKF"
     gene            6081..8141
                     /locus_tag="KRH23_001751"
     CDS             6081..8141
                     /locus_tag="KRH23_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase dimerization/phospho-acceptor
                     domain-containing protein"
                     /protein_id="HHS5225031.1"
                     /translation="MEKYRVLKLVSLIIISISFPLTILLVTIGLAEPKYNIQKTSTKS
                     GIFDISDDFYDSNIFDEGTMASLLPKFKLSVGGKLTSKEKGKFQQEGKSIDLSSSDSE
                     YDKIMINEQASEEYLSYLKNIKVYVINTYTGVFYTNTSYASLYDFKQKTKSYCNVEII
                     NKIGKSSYIKTINGEKFELNNLSLELNEVDEGFEAYVSFPEEPTIEDGIVYTNFQIFK
                     QATEKVRLFFVASLSLAIICLLSIILYIKIKGEVLKRNNVFLLIYSKIPMEFNVILVS
                     ISIAILTIYALAVSYHIDVIALVSLSLLIVSNNIFFINVQLSYLENKMCIFKTSIIVR
                     VILWLIKTVREVSNAIKKVSLARKVIVIVIISLALIMAISTRSIGMGLLFSICIFLGF
                     TIYITKRLSYLSYVIEGTERIKKGELDYKIKITGNDNFTSLAENINNIGEGLDRAIEE
                     QVKSERMKSDLITNVSHDLKTPLTSIINYVDLIKKEESIQPEYINDYINVLESKSKRL
                     KLLIEDLFEASRVSSGNIELQISKIDLVQLLRQSIGELEEKLSKNNLYLKLNVPNDKV
                     YIWADGRRMYRVFENLLSNIAKYSLEETRVYIDVYDYGENVKVTMKNISSYELNFDPS
                     EIMERFKRADESRNTEGSGLGLAIARDLVALQGGKFYIEIDGDLFKANLEFQKYEEEI
                     TNME"
     gene            complement(8347..8670)
                     /locus_tag="KRH23_001752"
     CDS             complement(8347..8670)
                     /locus_tag="KRH23_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HHS5225032.1"
                     /translation="MNNNYIFFIIIGMYIVTYLPRVLPMLIFSKKEMPDFLKKIMKFI
                     PVAILTSLTAKDVFFNGDSLYLSIANPKIISFMIVLLVAYKFKSIGISIITGVISIYL
                     FGIIL"
     gene            complement(8663..9364)
                     /locus_tag="KRH23_001753"
     CDS             complement(8663..9364)
                     /locus_tag="KRH23_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HHS5225033.1"
                     /translation="MERTQQLKESFIASIPIFLGYIPIGIVGGILLQKSGLSPFQIAL
                     MVTLVFGGSSQFIAASMISTGASVTSIVLTTFIVNLRHFLMSSNLNMYIKNKSPKFIL
                     PFCHTITDETFAVNYEKFTAGNWSDRNAIYLNFFCLISSVLANFIGAFLGESISIDSS
                     ISGFILTSMFIALIVSQIKNKIYIVVFISSIIISVILYALFKSNLVIIVASILASLIG
                     FFIEESYCKKEESYE"
     gene            complement(9642..11027)
                     /locus_tag="KRH23_001754"
     CDS             complement(9642..11027)
                     /locus_tag="KRH23_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HHS5225034.1"
                     /translation="MPINSFENYPMNWKPKRPSKGQILYKALAEQLEQDINNGFLLPG
                     TKLPPQRELADFLDVNVSTISRAFKICEKKGLISGVTGSGTFVSYDTRSNLFLMSSNN
                     KITFIEMGTMNPDFTLEEMNTLFKHIIKEIDFKTIFQYGQRDGAKWQKEAIAKLIYKA
                     GLETTSDSLLPASGGQNAIVAILAGLFQHGDRIGVDPLTYPGIKTAAKMLGIQLIPIK
                     QEDNEISEEGLLYACKNENIKGLYIIPDYQNPTTHIMSQNGRKMIANIASKYNLIVIE
                     DAIHSLLNETHLNPVASYLPNQTIYITSLSKIIAPSLRLAYISTPKQYREALSSALYN
                     INLSQSYFLTEIAYRMITSGEADKLINARRKSARRRNKIINQYLSGYNLLGNEECIFR
                     WLILPDGIMAEKFEIQALKEGVQVYASERFAVGKEKPISAIRIAVCATESTEELKAGL
                     SVLKRLLEEKK"
     gene            complement(11135..12373)
                     /locus_tag="KRH23_001755"
     CDS             complement(11135..12373)
                     /locus_tag="KRH23_001755"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF017390.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M56 family metallopeptidase"
                     /protein_id="HHS5225035.1"
                     /translation="MELFIEVIKFNIYISPLILFFILFTKKISKYTFKFNYFIYLLIV
                     VRMMFISKINLNILNINNTTINIYKHNIDNYIPYDQGITLDIFMYIWILGIIAISFYY
                     LRTNFKFYNYIENFKKEILEIDITSILDEQAKELSINKKLQIYKVKGIYSPAIIGLTR
                     CKIIIPEKKYNNKELRFIFKHELIHYKRKDNLFKLLISTICIIYWFNPILYLLKKYFH
                     ELCELSCDEIVIDKCTTSEIKEYAYIILDTIKYQKTLKYSSFVSQFLNKKNIILKKRL
                     DSMFNQDKKKINLGLKFLLTFIIIGSIFSINSNFKQNEDVEYTIGKINYNKNGETYGT
                     HIIDSNRNSIEPELIQTIGRGKKVGYVKKRDLYDCDNQPKTPEEAVLYTRKRNFNIFK
                     KTIPLYDKEGIKIIGRFEIN"
     gene            complement(12386..12763)
                     /locus_tag="KRH23_001756"
     CDS             complement(12386..12763)
                     /locus_tag="KRH23_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HHS5225036.1"
                     /translation="MIILKKIPKSELLVMNFIWDKGIDKIPAREVANYMEISHGWTKG
                     TTGKVLSRLSDKGFLEFEKDGRNTLYTIKVKHEEYLKFETKDFLELIHKNSIHSFISS
                     LDCGNEISDDDIKELEQWLKKRK"
     gene            complement(13282..13704)
                     /locus_tag="KRH23_001757"
     CDS             complement(13282..13704)
                     /locus_tag="KRH23_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HHS5225037.1"
                     /translation="MNTFKTEVLLKYSAKDIFNIFTKSARLNFPNFNEKKAVGTFVQQ
                     KNNKRFKVEITNFEKNRVYEIKTSNKRESTITRYELVHIDLENTKLIFIESESKRNIF
                     GKINSALVRVLFGKRQPEEFNKFIKKLEMELENNSVNL"
     gene            14182..17085
                     /locus_tag="KRH23_001758"
     CDS             14182..17085
                     /locus_tag="KRH23_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HHS5225038.1"
                     /translation="MELRDKLVNIINTENKKDPLTDVQIAKFLSTTRENITNLRKELN
                     ISNSRQRRYPYLKSAISAILQKNKNISISEITRELMTEGFNISRRVVEELLPKESLEM
                     DVVEESEEESNDPFETLIGNKGSLRNAVEQAKSAILYPPKGLPTLIIGESGVGKSLFS
                     RHMYEFAKQKKIVKESSNFVVFNCADYSDNPQLLLSLLFGYKKGAFTGAEYDTPGLVE
                     EADEGVLFLDEIHRLPPKGQEILFSILDRGKFRRLGETNAERKVSIMLIGATTENVET
                     NLLLTFRRRIPMLITLPPLHDRLLKEKIDLIYNIFQQECNRINAKIFVDKNVIEILAL
                     KKFSGNIGQLQNMIQVLCARAFMKFINSKDEDSESIVVVDINEVLKLKDSFKDTAFQE
                     IEYTEIRKYLKNAIFIPFNLEESSIKGSLLSDEYILPEDIYKTIEKKYYDLKSLDIED
                     IDIENILWTFILNRFADLKFNLDSNEEIFSMSDLNSFVSDSLVKLVKELMNDIVEKNM
                     NLEVNKNMFKYLAIHLEEAIKRIKLNQKIINVNLEKIKIDFSKEYEISKSFAIKIEES
                     IGIKISDDEIGFITLYIKSALKNEVKKDKVGLIIISHGRIATETVNVVKELLGVKFPV
                     AIDMPLDEKPINIYNKAVELSKIIDQGKGILFLVDIGSLTNIGQIVNKRTNISTKTID
                     RVDLLMALEATRKVSMGEEELDEIFFSLLKDRMGYNYELEKHIDKSNAIITLCLTGEG
                     TAKYISKTLEEKYDNTKCYQMSALDENLFCKIENLKETNNILAIVGTINPKIPGINFI
                     PYNKELFKNLDIYLSKSKQQDDRPVKSYERMLDEDLVIFEPDIYFKKDLLEYVCSILI
                     NKEYVEKDYLDSVLHREEMLPTYSKGAIGVPHGDSSTVNSTRFVFVKLKNPIDWGVGN
                     VNFIFMPVFQANDKEIVKNVLEILKDAEFMNNANKCFDKDAFRRIIFDKFKHL"
     gene            17118..17564
                     /locus_tag="KRH23_001759"
     CDS             17118..17564
                     /locus_tag="KRH23_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HHS5225039.1"
                     /translation="MNVDLISLGLESNDYESVIEELGSIMCKKEYVKETYINAVLERE
                     RTLPTGLDIGEMCVAIPHTDSKHVNESNVAVGILKNPVKFNSMIDPKDRLDVELVFLL
                     AVKNPDSQVKLLKDLMSVFQNIKLLKNIKNASTKEEVAKLLDFIEI"
     gene            17687..17989
                     /locus_tag="KRH23_001760"
     CDS             17687..17989
                     /locus_tag="KRH23_001760"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HHS5225040.1"
                     /translation="MKQFNVLSVCGSGTVTSSMVAGKLKEVLGNKGISITTTEARPTE
                     ALNLAQSGRFDFITFTSPLQTGDYGIPTINAFACLTGIGEEAFFEEVLTVIEGIDK"
     gene            18170..19576
                     /locus_tag="KRH23_001761"
     CDS             18170..19576
                     /locus_tag="KRH23_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HHS5225041.1"
                     /translation="MLEFMKSIIDTFGSAIIVPIIIFIIAKIFKVTTKKSFLSAVYAG
                     VALQGFTLILNSFTPIITPVINRMVESTGVNLPVFDVGWQATSLVAFSTSAGMIYLGL
                     GILLQTILFLIKWTDVFQPSDLWNNYSYMVWGAMVIGVTGNFPLGIACMVLLNLYSLL
                     ISELVAKRWSSYYRYPNCTIIAMHNVEASVFAVFADPIYNKLGLNKIKLNPKELEKKL
                     GFLGEPITLGLFLGMFIGILGNMTRINTMEAWGEIMKVGISTSAVMAIFPKVASMFAQ
                     AFAPITEAARKIMQKAGNREWYIAVNDAVGYGEPATLISGLILIPIMLVIAMVLPGNK
                     VLPVVDLLAIPYMVQGLVAIHNGNIPKVLVSGIIWFGLGLYVCTSTAPLFTDMATNIG
                     VAIPAGAMLITSFNILGKPLMGLVFFAFLSANPIYIGLSVVIYFVLWVLFRKNKTSIL
                     DYLEKQALKNVEEEPVAV"
     gene            19920..20978
                     /locus_tag="KRH23_001762"
     CDS             19920..20978
                     /locus_tag="KRH23_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HHS5225042.1"
                     /translation="MGNKMRASVLYNVGDVRYEMVNIPEITDTQVLVNVKYVGICGSD
                     LPRSMVSGLSGNTKYPLILGHEFSGEVVKIGEKVNHINVGDRVAVAPLVPCRKCDYCN
                     EGNFGLCDDYSIIGTRVNGAFAEYVRVPEEHILKLPDTLDYETAAGIEPATIAYHGIS
                     KSNIRVGDSVVVLGCGPIGQFVIQWAKVFGASKIIAVDIFDEKLELSKLLGANYILNS
                     KEVNVIKEIKKITNGGADVVIETAGSRFTQEQSLFVAKKRGNIVFVGISHTELPLSAD
                     ATECILRGELTLKGSWNSYTSPYPGRAWTATLDFMGKGDIIFKPMISHKIGLNEVGDF
                     LSKMSKREINFNKILVEI"
     gene            21077..21763
                     /gene="araD"
                     /locus_tag="KRH23_001763"
     CDS             21077..21763
                     /gene="araD"
                     /locus_tag="KRH23_001763"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0008742 - L-ribulose-phosphate 4-epimerase
                     activity [Evidence IEA];
                     GO_process: GO:0019568 - arabinose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HHS5225043.1"
                     /translation="MLENLKEEVLKANLELPKKKLITYTWGNVSGIDREKGLVVIKPS
                     GVEYSNMTVEDMVVVDLEGNIVDGKLRPSSDTPTHLVLYKEFEELGGIVHTHSSWATI
                     WAQIGKSIPSCGTTHADYFYGSIPCTRKMTREEICNEYEKETGNVIIEEFMGRNPIHC
                     PGIIVNDHGPFTWGKDANEAVHNAVVLEEVAKMAYYTELMSPDNIMDKVLMNKHFSRK
                     HGKNAYYGQK"
     gene            21781..22428
                     /locus_tag="KRH23_001764"
     CDS             21781..22428
                     /locus_tag="KRH23_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HHS5225044.1"
                     /translation="MLDSLKGKIVEIAIKAEHYGLCKEKTGNFSIRDKDTGYILITPS
                     GIGREELKVEHICVLDLDGNVIEVEKGIKPSSEVLMHIEIYKTRENINAISHTHSLYA
                     TAFSVAKKPIIPIVYESVNYGGYVDIAPYERPGTLKLAKSVSKLLIDTDACLLERHGL
                     TTVGNDLDEALLKSRYVEEVAEIYYRSLVLNQFKELEVVDVDEFKSWKYPEEIKF"
     gene            complement(22601..23968)
                     /locus_tag="KRH23_001765"
     CDS             complement(22601..23968)
                     /locus_tag="KRH23_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005283 - amino acid:sodium symporter
                     activity [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine/glycine:cation symporter family protein"
                     /protein_id="HHS5225045.1"
                     /translation="MNLIDILNKVDAFIWGPPLLVLLVGTGILLTVKLGVVQITKLPR
                     ALKLIFSAENKGSGDVSSFAALCTALAATVGTGNIVGVATAIKAGGPGALFWMWIAAF
                     FGMATKYSEGVLAIKYRTKDKNGQVSGGPMYYIVNGMGEKWRPLAIFFAISGILVALL
                     GIGTFTQVNSITDAINNSFGIDPRITGVVLAVFVALVVFGGLKSISNVATKIVPFMAV
                     IYVVICGIILISFWNKIPETFMLIIKSAFTPTAATGGFLGATMSLAIRNGIARGVFSN
                     ESGLGSAPIAAAAAKTEWPAEQGLISMTGTFIDTIIICTLTGFSLVISGVWCSDLNGA
                     VMTQAAFNGAIPTFGPILLTVSLTLFAFTTILGWSYYGERCFEFLFGVKGMNGYRTVF
                     VAMVLLGAFLKLEVVWIIADIVNGLMAIPNLIALLALSPIIVSETKKYFEHINSPENQ
                     IKKNA"
     regulatory      complement(24158..24246)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            24673..26793
                     /locus_tag="KRH23_001766"
     CDS             24673..26793
                     /locus_tag="KRH23_001766"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HHS5225046.1"
                     /translation="MGKILVLAEKPSVGRDIAKVLGSKNEKNGYIEGPKYVITWALGH
                     LVTLADPESYGERYKSWSLEDLPILPKHLKTVVIKKSGKQFNTVKSQMNRNDIDEIVI
                     ATDAGREGELVARWIIEKSQVKKPIKRLWISSSTDKAIKDGFAKLKSGKEYENLYYSA
                     IARAEADWIIGINATRALTTKYNAQLSCGRVQTPTLAMLLKREEEIRNFKPKEYYGLE
                     LIATKGNSDIKFIWNDKNNNSSTFSKEKIESTLKKVKGVDIKISEVNKSYKKKYSPAL
                     YDLTELQRDANKMFGFSAKETLSIMQKLYEHHKVLTYPRTDSRYLTSDIVGTLKDRIK
                     AVNISDYSKICNRLLKSNIIANKSFVDNSKVTDHHAIIPTEQKVFMSDFSDKERKIYN
                     LVVKRFLAVLSPPFEYEQTTISATVEGEIFKAKGNKVINLGWKESYKDIEDEDEYESI
                     PNILEKDVLKVKGLKITSGKTNPPPYLNEGTLLTAMEKNGLGTVATRADIIEKLFNSF
                     LMEKKNKDIYITSKGRQLLDLVPVDLKTPELTASWEKKLLDISKGKLSKNTFINDMKD
                     YSKDIVLEVKNSDNKFKHDNLTKNRCPECGKFMLEVNGKKGKMLICEDRECNTRKTIS
                     QVTNSRCPNCHKKLELRGEGEGRLFTCSCGYREKLSSFNKRKQEEKQKASKKDVNQYL
                     KNQNKNQETFNNPFAEALAKLKNK"
     gene            26897..28150
                     /locus_tag="KRH23_001767"
     CDS             26897..28150
                     /locus_tag="KRH23_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein FliS"
                     /protein_id="HHS5225047.1"
                     /translation="MDLSGIFKYYCKECENTWNNSSVELFENIETYSKDSQKKREKEL
                     DKLLNTISVHLERYPSDAVLRKMWVKKGEVFLQKTLEKENIFKLEKMDVEDRKKFLEI
                     TKQFIRDARKFDDDLPIGDIMQAMRNVWISNALQLLFGKEVYYSKANFAYSMLYPYTD
                     NYLDNTNIDKNDKILFNNWLEKRLLGEHTKSKDYHESKVSQMIDYIESVYPREKFTEV
                     YESLLLIFKSQVNSLKQHGKENHLCKEDLLSISIEKGGSSVLVDGYLISGLMTKEEIE
                     FCIGYGFLLQISDDLQDIKEDLKYNHKTIITEMSKEGTLDKVVNKLINFTIELIDSFK
                     INNKNKSVITMIKNDCLMLILFSVVYNAEFFSVGYIKEVEKFIPYTIDYSLEIEEKIK
                     EKFKNIDVLNNENEYKEMIDIICAE"
     gene            complement(28304..29365)
                     /gene="ytvI"
                     /locus_tag="KRH23_001768"
     CDS             complement(28304..29365)
                     /gene="ytvI"
                     /locus_tag="KRH23_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation integral membrane protein YtvI"
                     /protein_id="HHS5225048.1"
                     /translation="MDIQKQKNFIIKFTYVVLITSIVYIVLKFLLPLLMPFVISFIIA
                     SILRPIIRLITNNTNLNRTLISIVILLIFYGLCIFLLVSFGVKIFASVSDVFFRLPEI
                     YKSSIQPTLNTLFSKIDASTPNVNLALILGWDNISQSMMSLVASISTNALNAIASIAS
                     KTPAFMLKLIITLIASFFFTFDYQKIVNFILKQFPEKSQFMIINIKNSSINALLKLLK
                     AYAILLSVTFIELLIGLTILKVENAFTISVIIALVDILPVLGTGSILTPWMIISLING
                     NINLAIGLLILYIIITVVRQILEPKVVGHQIGLYPLITLMCMFVGAQLFGIAGLFGFP
                     IAATIIKNLHDNGIITAFK"
     gene            29639..30379
                     /locus_tag="KRH23_001769"
     CDS             29639..30379
                     /locus_tag="KRH23_001769"
                     /EC_number="3.1.3.48"
                     /inference="COORDINATES: protein motif:HMM:NF024744.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004721 - phosphoprotein phosphatase
                     activity [Evidence IEA];
                     GO_function: GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein phosphatase"
                     /protein_id="HHS5225049.1"
                     /translation="MKNFRDLGGNKTEDGRTVKKGLFYRSAKLSNLSENDIKILRELN
                     IKYIFDYRSDEEARKHPSTIISNIKNIRIPAMRELEESGGSFGSIEDMIDGLFEKDGA
                     FNMLNNSYYNLPINNPSYKKLVELIRDYSNLPILNHCTAGKDRTGVGSAIILMILGVS
                     RENIMKDYLKSNDFADKEIERFIEYKPKFKDIPKENLKYIFGVNEEYMKTAFRRIDEE
                     YISVEAYLYGEFNLNKEEIRKLRNQYLE"
     gene            30391..32169
                     /locus_tag="KRH23_001770"
     CDS             30391..32169
                     /locus_tag="KRH23_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HHS5225050.1"
                     /translation="MSLNITARQINIIKILLNSKDTISGIALSQEIGCSSKTIQNEIK
                     DINKQLRNGKILSIRGVGYKLEGSFDEVNLNSNLYDDVDRVEYIIRKILTLSNEEKNT
                     IKLEDLADSMYVSVSTVKNDLKEVKRILEKYSISVKSKHKQGICVLESEDKILNCIVD
                     LSNKRDNQLSLNDFLNDDIKERKLLIKKLLLDILNENGLVLTDIEFKSVLNNILVMLS
                     RHKYNEKEFIENYIENYRSKRSSILENEQNKEIIINSIKTFCKNLKLATSIDISNDKV
                     FEEFLYKHISSLCKKIKLGINQSPIMAQDIKIKYPFAFELANIAKKTIEKDLKIEINE
                     DEVANIALHIGGAVERASYNNKDKVFKTIIVCTSGIGTSMLIKAKLENIFKEKLEILK
                     IIPSYLVEYIKVIDVDFVISTVPIEVGDVPVINISPILSEKEIRLIEKYIETGNIYLD
                     LDIKSLFDSELFFTDLVFKRKEEVIDFMASKLVQKGYIDEDMKKSYFEREKIATTEIG
                     NMVTIPHGAIGKIFDNKIAIGILKKPISWEISDVRLIIMLALDKDKILDYEVIFSKIY
                     KRVDSIAKVISICENSSFEKFVNLFN"
     gene            32336..33253
                     /gene="pfkB"
                     /locus_tag="KRH23_001771"
     CDS             32336..33253
                     /gene="pfkB"
                     /locus_tag="KRH23_001771"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008662 - 1-phosphofructokinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HHS5225051.1"
                     /translation="MIYTVTLNPSIDYIVKLDELKTGSTNRVKEEYVYPGGKGINVSR
                     ILKELGNDNTSLGFISGFTGEYIIRTLEEKELKTDFIKIKSGFSRINVKIKALKETEI
                     NGQGPNIDDEDIDTLYKKLDKLNQDDILILAGSIPSTLDEKLYENIMARLEKKNIKVV
                     VDATKNLLLNVLKYKPFLIKPNNDELEELFGVKLNSIGDMVKYARRLKEMGAINVLVS
                     MGKDGALLITKEDEVLISDVPKGKVKNSVGAGDSMVAGFISGYLNTGKYDYALKLGAA
                     SGSATAFSYDLAKREYIDKLVNEISVKKF"
     gene            33290..35209
                     /locus_tag="KRH23_001772"
     CDS             33290..35209
                     /locus_tag="KRH23_001772"
                     /EC_number="2.7.1.202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005351 - carbohydrate:proton symporter
                     activity [Evidence IEA];
                     GO_function: GO:0022877 -
                     protein-N(PI)-phosphohistidine-fructose phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_function: GO:0090563 - protein-phosphocysteine-sugar
                     phosphotransferase activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIABC"
                     /protein_id="HHS5225052.1"
                     /translation="MKIIDLLDEKSIKLNLNSKTKSEAIEELVDLVANSGNLNDKENY
                     KKAILAREEMSTTGIGEGVAIPHAKNSSVTKACIAAAVSKEGIDYESFDGSLSNLFFM
                     IAAPDGANNTHLEVLSRLSTILMDEDFRNKLINSSSEKEFKEIIDKKEREKFSEEYQD
                     EKVTEKNIIDTKENDANKYPKVLAVTACPTGIAHTFMAAESLNKMAENKGVSIKVETN
                     GSAGVKNKLTKDEIENATCIIVAADKNVEMARFNGKKVIKTKVADGIHKAEELIDKAV
                     NGDAPIYHGGDGSHNESNEESESGFRKVYKHLMNGVSNMLPFVIGGGILIAIAFLLDD
                     YTINPSNFGSNTPIAAFFKGIGDKAFGFMLPVLAGYIAYSISDRPAFVVGFVGGALAG
                     DGGSGFLGALLAGFIAGYLVEGLKKIFSVLPASLEGIKPVLLYPLLGTLLMGIIMTFL
                     VIPPVTAINNAMVGFLNGLGGTSKIFLGLVLGGMMAVDMGGPVNKAAYVFGVASLESG
                     QFEIMAAVMAGGMVPPLAIALATTFFKNRFTKEERDSGKVNYVMGLSFVTEGAIPFAA
                     GDPLHVIPACVGGSAVAGALSMLFNAALRAPHGGVFVIPVVTHPFAYILAIAVGALVG
                     MMLLALLKKPLNQEV"
     gene            35805..37331
                     /locus_tag="KRH23_001773"
     CDS             35805..37331
                     /locus_tag="KRH23_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HHS5225053.1"
                     /translation="MNESYWFLNSSPKEYNKLGENIKTDCLIVGGGITGLTTAYLLAK
                     EGKKVVLVEADKIGYGTSGRNTGKVTCQHDIFYSKIEKKYGLDKAKSYYNANNEALNL
                     VEQIIEENNIKCDFKRETSFVFTEKEDTIKNIKDEYRTCKKIGINCEYHETIENIPLD
                     IKGAISFTNQGQFNPKKYIDGLAKVAVNLGLKIYENTPVVDLEKGKICRVKTREDNII
                     EAENVIISSHSPWYDGLNFYFAKEYAERAYLMVAVLENKLADGMFISIDDPSITFRQY
                     NDGSENLLIFGGGDHKVGQGGTEKEIFDDLEHYGKEVFKVKDFKGKWSAQDNMSFDNV
                     PYIGYINKREDNIYVATGFSKWGITNGTAAGIIIKDLIINNNSDYKDTFNPSRLGSYF
                     SKDFIKENANVAINYVSGKLKIGSGDMPKNNGEGKIVNIDGKRYGVYKDDNGDFYIVD
                     TTCTHLGCELNFNSEEKTWDCPCHGSRFDYKGNILEGPALKPLKLYGHGDNDVNPKLL
                     "
     gene            37359..37916
                     /locus_tag="KRH23_001774"
     CDS             37359..37916
                     /locus_tag="KRH23_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5225054.1"
                     /translation="MNKLLKPITILLYIVYILSAVFFVANKEYGSLGLVAISLVGTFI
                     LSFINKQTERLLSKELYIMLALFIMFSSLLGTCFNFYDINYYDDFLHLWSGIISCIVA
                     FSIIKYFYTQREISKMSKVFLVIFLFMFSMGVASLWEIGEFLMDTFVGTTTQAGGLED
                     TMIDMVDALIGTIITIPFIVKKSNI"
     gene            38438..39481
                     /locus_tag="KRH23_001775"
     CDS             38438..39481
                     /locus_tag="KRH23_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5225055.1"
                     /translation="MLKKWFGIVKKRQKSESVKEEGEVILKNEKILSEEKLIDEEGVV
                     VNIDNEILTKVEVVNDDNEIEEKIIEEDWLISENTIKLDDKEAIINDKNIELCKKEVQ
                     VEGEKIDLNKFEGLDQNENYNLEKNVIEEKEVSECLTEEDLEYIKEIKIKRGKSIKAI
                     NLYTKEEWVFDTHIQCSKKLKVPLGYIRENLKYGYMDYFGDAINYLSEVLNIDEYCKS
                     EWSYLDNSKSPSEIFNILNNKIFSIRLSNEKRNEILTNDKIEALKMNYRFECIDEEYD
                     EYFKKYKSIIKRGGKKKVELVNKKGDILEIFKSLEECAIYLQKEKNEVIQMLKYGDTK
                     VGRNFIRYSLRSI"
     gene            39592..40734
                     /locus_tag="KRH23_001776"
     CDS             39592..40734
                     /locus_tag="KRH23_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HHS5225056.1"
                     /translation="MSEEKNPKENTLDESKNSDNVNSKKDDVSDEKNTDNKVKKREIK
                     LNNKTLKAIVAIVAVGAICLGGGYVFGKEAGRKLPATSKHYNSSEVVATIGDKKITGE
                     MLRKRMEPLFYLNAKTTMTDDEIRSYESNMIETMITSDILSSEAAKEKISITNDQLDA
                     QYNNLMSSIESAMGMTKEEFLKQFDLTEKYIKDDMKKELVASKYLNEKSKVTDKEAEN
                     YYNKNKSNYLQVRASHILIKTVDDKGKQVSSSKKAELKKEAEEILKKAQAGEDFATLA
                     KKYSEDSSAESGGDLGFFGKGQMVESFEKAAFALKKGEVSNKLVESDYGYHIIKKTDE
                     KYQPFEEVKSDLVSSLTSEKQNLLIQNLKEKYNVKITDKYQMKAKE"
     gene            41188..42579
                     /locus_tag="KRH23_001777"
     CDS             41188..42579
                     /locus_tag="KRH23_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_function: GO:1904680 - peptide transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015833 - peptide transport [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HHS5225057.1"
                     /translation="MSSTESVSKKSGHPKSFWLICMTILWERFSYYGLTALLVLFFTA
                     SVAQGGLGLSTQEATSMFGLFTGLIYLTPLVGGWLADKVLGQQKCISIGALLIAIGDF
                     VLFASSTSIAMVWVGLSIIILGNGFFKSSCSNIVGDIYPKTDVSRKDAAYSLFYMAVN
                     VGAFIAPIICGLLSDNVFAVRGASGDIVSYGYKMAFLICGIGMMLGMIIFTLLAPKLL
                     NEVGKYPVTKGNKGEKIEYGPLTKLEKNRIIAMVILFLFVVLFWTAYYQTQSSFMIYV
                     RDNVNRTLFGFEMPVAWLTSLNAILCVALCPVLATLWVKLSHTKRGDFSIPVKMGLGM
                     IIMGVGFIVMVFATLANGPDGMVKASILFIVLTYIFTTVGELFLSPIGLAMFNKLAPA
                     KYATLSMGAWYLTSFFASLLSGKIAGFTATLGFLQIFGGIATVLIIFGLILLGIRNVL
                     TRLMAMDLLTKEK"
     gene            42832..44625
                     /locus_tag="KRH23_001778"
     CDS             42832..44625
                     /locus_tag="KRH23_001778"
                     /EC_number="3.4.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004177 - aminopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HHS5225058.1"
                     /translation="MNIKDRLSGLRKFMEEKNIDAYMIPSSDNHQSEYVGDYFKSREF
                     ISGFNGSAGTVIVTKDEAGLWTDGRYFIQAESQLEGSTIKLFKMGQEGCPTTDEYLYK
                     NIPEGGTLGFDGRVISAREGATLAEKLSKKGIKIEYQYDLIDSIWPDRPALSDSKAFL
                     LDVKYCGESFSSKLARLREKMSEKGTSTHVITTLDDIAWLFNIRGGDVKYNPVVLSYA
                     VITLKEVYLFVDESKLNEEILNELAKENVQIKPYNDVYEFVKNIDKTEKVLLDGTKLS
                     YTIYNNIPCEVEKVDEFNPVMFFKAQKNEVELENIRNSHIKDGVAFTKFMYWLKKNVG
                     KMEITEISATQKLEDLRREQEGFFEPSFNTIAAYKEHAAMMHYSATPESNYKLEAEGL
                     FLVDSGGQYYDGTTDITRTTVLGPISDELKLHFTSVARGMINLSKAKFLHGCRGYNLD
                     ILSRSCMWNMGIDYQCGTGHGIGFVLNVHEAPNGFRWRVVPERFDSAVLEEGMVTTNE
                     PGIYIEGSHGIRTENEIVVRKAEKNFYGQFMEFEVVTLAPIDLDGIVPELMNKDEKDY
                     LNWYHKLVYDKISPFLTDEEREWLKVYTRAI"
     gene            complement(44706..46088)
                     /locus_tag="KRH23_001779"
     CDS             complement(44706..46088)
                     /locus_tag="KRH23_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_function: GO:1904680 - peptide transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015833 - peptide transport [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HHS5225059.1"
                     /translation="MSVLKTQEKLKQPRDLYFCCSIFTFVGLAYYGMKLVLLLFLAEQ
                     VSKGGLGLTPAESASMLASFLAWTYFSPVIGGWVSDRFLGPKNCIILGMLMVSIGYFL
                     GYIANSKMDINIMIFLSGLGIGFYKGNLHTMVGNLYTNDDPRKDGAFSITYMATNLGT
                     LFGPLICGLVANEWFAMKSGLSISMYGYRYVFLFSSITVLIGLFFFIFGNRKFYKPLN
                     NDPSNGRESIRKSLEYKKMLASRPLTLIEKKRIIVILVLAFFTVFFWIAYNQASMSIA
                     LYTKEHINLTVGNFQIPTSWIDSYNGLLCVILGPISALVWVKLSQTKKGDLSVPKKMS
                     LGFILLAIAFLFMIVAVIQTGTDPNSIHKASVFWVVGFLTFQSIGEICFSPVGYGMVN
                     KLSPEKYISFLMGVWFLGKFAANKLSGYTQAIIDQLGMLQVFIVIPSFLLIFGIILLI
                     MNKKLVELSN"
     gene            46346..46693
                     /locus_tag="KRH23_001780"
     CDS             46346..46693
                     /locus_tag="KRH23_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HHS5225060.1"
                     /translation="MIRKKSELQVEVKENLNGGIGKVKLENIIQNEELKGKGRLFKRV
                     ALPVGSSIGVHDHTTDFEVYYILKGKGKVFDNGEFVEVNEGDVVYTADGEKHSIENIG
                     EEDLEFVALVLYM"
     gene            46711..47745
                     /locus_tag="KRH23_001781"
     CDS             46711..47745
                     /locus_tag="KRH23_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6398 domain-containing protein"
                     /protein_id="HHS5225061.1"
                     /translation="MTGKIEEIKDKINRFCNSNLNQEYKDISFKILQNLLDNNKEIIH
                     SSRADIWSSAILNIVLEQNLLYNKKHPLHITKKEFSKQIGVSLNTINNKSSLIKDVCS
                     IDFLNQDTIAISNVEFWVKETNSKSKSVDLDLEKKKILYKRYIKLSQDANSDIESIRY
                     MEEAVNIGKSMITKEDKELGFWKGLSTRAYMIALESLARKLESINNLKESKKVLEYLI
                     EINPSDEQGIRYKLLNVLIRLNDRTSINKLFELYKEEKSATWMYSKALYYFKNKSMFL
                     ANDSIKVARSKNKYVGLYLLDWRNAFGREFVTEEEKAEAVYYYDENIVIWNEVKGSMD
                     WLLKKMLESS"
     gene            complement(47794..48843)
                     /locus_tag="KRH23_001782"
     CDS             complement(47794..48843)
                     /locus_tag="KRH23_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIC"
                     /protein_id="HHS5225062.1"
                     /translation="MEINYKKRNFKSFAKRKNIEISVQRYLIDALSYMALGLFSSLLI
                     GTIFNTLGDNFNISLFTEVISPLAKQVTGPAIAVAIAYGLQAPPLVLFSCALVGACGN
                     ELGGPVGAFVATLFAVEVGKLVSKETKIDILVTPAVTILIGVLVAELIGPAVSAFMTS
                     FGNIIMQATTMQPIIMGALVSALVGIALTLPISSAAICMMLSLGGLAGGAATVGCCCQ
                     MVGFAVMSFRENGVGGLVAQGLGTSMLQVPNIIKNWKIWIPPTVASILLGPLSTTIFK
                     MENIPIGSGMGTCGLVGQFGTVTAMQSAGKGGISMWVGILLLNFILPAIVTLLISEFM
                     RKKGLIKPEDLKLDV"
     gene            49118..50653
                     /locus_tag="KRH23_001783"
     CDS             49118..50653
                     /locus_tag="KRH23_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5225063.1"
                     /translation="MIFVKNKKYRKIAIIISIPILLVAQYYLFKFGILRPMVKGVEIE
                     IVDGEYVKDIDKYVVKLNETVTLSTGEYIKVPSYAKNPNIWFNVLDNSGTLKIDGNKM
                     TALKVGYSSVGIMKNSRVLKKATIKVVDPEVESLDMEINGDLKHVGDSATIESTIEVD
                     YDKFKKSYKPVYKSSNENILKIKGNKVSAVGVGKATIYAKCGNKEIERTFRIQARVAE
                     INMDDIKIEVDQNEKLKPDIITSPPGLEPPKIYYELVDSKLPVERAISLSSNGNVVGL
                     REGKDRVRITCGDKSKVITVTVVKETITNDYIQNLVGSHKIVNNKVIIKLEWDYMKDV
                     FDYDIYLKDKLSGESFKKIKSITINESDLGKSNKVYATIEVDMKGNQNIDFDIYVIGK
                     KDSDTTKPSNVINITNGNGNSNNDNNIKDMRVENISANVDRDNNVIRVNWSSISHKDC
                     TYSIYVKNNTNGDGEFTLYQSDIQGNEHTISIPEGDLNLDIYVVANYNGNSSQNSDVI
                     NVR"
     gene            complement(50839..51525)
                     /locus_tag="KRH23_001784"
     CDS             complement(50839..51525)
                     /locus_tag="KRH23_001784"
                     /EC_number="5.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047661 - amino-acid racemase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate/glutamate racemase family protein"
                     /protein_id="HHS5225064.1"
                     /translation="MKTIGLIGGMSWESTITYYQVINTVIKERLGGLHSSKCILYSVD
                     FQEIEECQSSGNWEKSAKILADAAIKLQEAGADFIVICTNTMHKVSDKIQESVHIPLL
                     HIADVTATVLREKEIKKVALLGTKYTMEQDFYKNVIINNGIEVLIPNEEDRIIVNDTI
                     FNELCLGIISESSKKAFLSIIDKLGKQGAEAVILGCTEIGLLIKQNDTSIPLFDTTVI
                     HAIEAALNSI"
     gene            51650..53032
                     /locus_tag="KRH23_001785"
     CDS             51650..53032
                     /locus_tag="KRH23_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HHS5225065.1"
                     /translation="MPINSFENYPMTWKPKLDNRKPPIYKTLAMLLEEDIKRGNLNPG
                     DKLPPQRELADFLDLNLSTITRAFKLCEEKGLICAKVGKGTFISSDVNVSNTLLYQTE
                     SKDIIELGTVHPPYEQNTYIIDFIKNVLKQPEMDRFLRYMSPSGTYMQKKSIAKWIER
                     NNVYTSEENILLSTGGQNAICATLLGLFKAGDRIATDSLSFSGIKSIAKMIGIQLVPI
                     PQENNEISIEYLESYCKNENIKGIYLIPDYHNPTTHTMSDLSRKKIAKIAKQYNIIII
                     EDAINSIFRDGIQTPIFSLASDNTIYIFSTSKFLCAGLRVAFVVAPKRYIENLENALY
                     NMNLMVSPFTAEIVHRLLYSPIIDKIIEEKRDAIIERNEVADKVLSDYNLIGDKNCSF
                     RWLLLPDELDGKSFEISAKNLGVQVYCAERFSVGNSTVPKAVRICVTAPKDVEELEKG
                     LNIIKSLLKS"
     gene            53434..54702
                     /gene="eam"
                     /locus_tag="KRH23_001786"
     CDS             53434..54702
                     /gene="eam"
                     /locus_tag="KRH23_001786"
                     /EC_number="5.4.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016869 - intramolecular aminotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0006536 - glutamate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 2,3-aminomutase"
                     /protein_id="HHS5225066.1"
                     /translation="MNEQTRISLERAAELKSKIDDYIQARKTINRGLEKEEEINKRKQ
                     KILSILNGTEEDWNNYKWQLSNRITDVDTLSKIITLTKKEKEYIKEVGTQFRWAISPY
                     YLSLIDPEDICDPIKLLSIPTHIELEDEQEDLDPMGEEYTNPAGCITRRYPDRLIINV
                     TNECAMYCRHCQRRRNIGQQDSHKSKAIIQESIDYIRENEEIRDVLVTGGDALTLKDD
                     YLEWILSQLKEIPHVDYVRLGTRTLVTMPQRITDEFCNMLKKYHPVYINTHFNHPMEI
                     TKESKEACEKLANAGVPLGNQAVLLNGINNDKFVMRCLNQELLKIRVKPYYIFQSKHV
                     KGTKHFNTSVDDGLEIMEYLRGYTSGMAIPTYIVNAPKGGGKTPLLPQYLVSKGTDYV
                     MLRTWEGKVIKMEDEPAVDIKKLIKEQAQD"
     gene            complement(54795..55151)
                     /locus_tag="KRH23_001787"
     CDS             complement(54795..55151)
                     /locus_tag="KRH23_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5225067.1"
                     /translation="MKKALISLLVLSCLLLTAPVNESSYADSQKNVPVSQNTKLTQEQ
                     AKELLVKYNNEVDYIYQGNASDFEALKAKNLNGYVFLPDADGDIGYFVNENTSEIYYF
                     HPSGYLELVNQQQNNK"
     gene            complement(55302..56396)
                     /locus_tag="KRH23_001788"
     CDS             complement(55302..56396)
                     /locus_tag="KRH23_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HHS5225068.1"
                     /translation="MQDKKIYLNIVLTVVVSYILIKVIDNYKYFFGVISLLMSLLTPF
                     IIAFVLAYIFNPLVKFLESKLNFKRIYSLLLTYGVLIVILISFILFTVPSIVNSLADL
                     VAQIPTYIDKTEQFLFDLGKSLQSVDPNTLKEYGDKIMSVMPKFSNLLIGSLGGIFST
                     TFSVGKFIVQFLLGFIICFYILLEKEKFLLFTKKVVYISLGKKYGDFIIELCQSLNLN
                     IGKYFTGKILDSFIVGVLSGIGLYFLKSEYALLFGTLMGVMNMVPYFGPVIGMAPVVI
                     INLFSNPTIALTSLIYLIIIQQVEVTFIEPKIVGGQLGLSPFFTILAVTVGGGFFGIP
                     GMILSAPVMGVIKIYFCEFVNRRHDKIQME"
BASE COUNT        22466 a         6276 c         9145 g        18750 t
ORIGIN      
        1 tagattaact atgtggattc aaaattaaat aaacaaagaa agcacttaca aatatgtagg
       61 tgcttttatt ctgctcaaaa ttggttggtt gggtaaaata attagaaaaa gttagtaaaa
      121 acctattgac tgtaactcgt tacaatattg ttattaatgt aacgagttac agaaaagagg
      181 tgaataaaat agcaactaaa agtagggcag agtatatgaa aaatcgtcga aaagataaaa
      241 gaggttttag tgtactttta gacaaagaaa agttagataa atttgatgaa gtattagagg
      301 aaaagaatct aaccaagaaa gaatggctag aagaaaaaat cgacgaggaa ctggaacaaa
      361 aggaataaaa aataagggtc actcccaccg accaaagttt gagtaacccc tatgacgtat
      421 actatcgtat atcaattata atatatgtca ttccttaaaa aaaatcaatt attaaggagt
      481 gtaatattat gaaaaatgaa ttaatgatgt ttgaaggaaa agagattgaa gtatttgaat
      541 ttgaaggaag aattttattc aactcaaaag atgtagcaaa ctgtttagac ataaaaaatg
      601 ttaatgagaa tataagactt atgaatgaaa agcaagttgt aaagttaaga aattcggata
      661 tcagtaatac tgacatccga aaacttaata atgctggaga aaattttctt actgaaagtg
      721 gagtgtataa attaatcttt aaatcaagaa aagaagaagc tgagagattc caaggctgga
      781 taagtgatga agttttacca agcataagac aaactggtgc atacataaat aataatgcaa
      841 taccgaaaag ttgagagaaa aagcaagtga gattgaaaaa ttacagttag tttataacag
      901 tacatctatg ttaaaagaat tgctagatga tgcaggcttt gacaataaat caaaactatt
      961 aacagctaaa acattatata agaaagcaga aattgattta ccaatagaga taaacgaaga
     1021 agaacattat tttgatacaa aacaaatagc atctaaactg aaaatatatt ctaagagtaa
     1081 taaaccagct cagatggctg tttgtgagat tattaaaaag attgatttag aagatggtga
     1141 agttaaaggt gtttgggaaa ctaatggttc ttggactggt actgtaaata aatatacaaa
     1201 gagtgtaata gataaggtga gaacttggat agaggaaaat aatagaccta ccaagattgc
     1261 aggtgagaag aagaattatc atgtatttta caaaattgag taaatttatc agttgtatta
     1321 aataatttag tttagttttg tggggattaa tacaatgtgt gagaatttac ttgataatat
     1381 gtatattgaa aagagaaaag aagaatatag aattaaactt ttgaaaataa gagaaacaga
     1441 tatagatata tataataagt tagaaagtat agtatataaa ctttctgaga aaaaattaga
     1501 gaaaaataat aaatagacat ataaagcact tggatattct actgtttcaa gtgctttgtt
     1561 tggtataaaa tggtataatg gagatagaga attatattaa cccaaaaatg gagaaaatag
     1621 agaagatgat ttagttgacg ctttatcagt aggagtactt gcaggtaaga cagaatctct
     1681 agtacgatta gttggagatg gaataagtga tactcaaaaa agtttaataa ataaaagaga
     1741 atttagaaat ataactcaaa ttggtggaaa tggaaatgag aaagcattta gtgaagtaga
     1801 aaacttagtt aaatagatta gaaggtagca actagagtta gttgttacct tcttttttta
     1861 tactttctct ctctaagtat tttctttttc atatcttcta atacatctaa tgcagtagta
     1921 taaaattgta tattattttt ataaggtata gctattggaa gaatgccctt gttaactaaa
     1981 aaaataagaa gtacaataaa taaaagtgtc ataatcattc taataaaata attagtgata
     2041 tctgataaat caaatgttaa gttaattgtt gtagaaaata caacagccat aatagatata
     2101 tacaaagcaa aaatggggtt actatttttt tgtaactgtc ctttaagcct agattgctct
     2161 atttctatat cttgaatact ttttatggaa tccatttcac tataatactt ataaactttt
     2221 aaataatatt ttttatactt gtttaaagct tcttcattat ctttaaggtc tttgtcactt
     2281 aactctgatt taacttcccc aaaatctata aaatccctcc tacaatgtta tataatatac
     2341 tttaatttat agcatattta agaacttata tcagcaattt gtcgaacaat tttagctaaa
     2401 aatagagtat aatgataggc ttattattta taagatatta ttttttatat agttatatat
     2461 ttctttctaa ttagataata taatgctgtt gttataatgg ctactaatat tattgctaat
     2521 attgtaatat ctaatcttct tgtaaataag cctattgcta tatactcaag acctgttaca
     2581 tagcgataaa gtacttctag tttaacagtt tttttcttat ctatatttcc atatattgat
     2641 tctaatttat taaaatattt tttactacaa aaagcagttt taggtttaat taaatatatt
     2701 attgtagttc ctattataac tattattcca ataagtataa gattgatatt tccaaaatcc
     2761 atagcagata cctcctatta aatttgcttt tcttaatcaa agtatatcag taacacaagt
     2821 acaaagagta tctaaaatat tacaaatatt aacaggatag ataaaactat agtaaaaatt
     2881 gtaataataa agcgaacgaa aattatcata ctaaaacata agacatgtta taattgtatt
     2941 agatagaaga ttaacataca ccaaagcact ccttataata aagagtgctt atttttttga
     3001 aattcatcaa tatataaact atcaagaacc ttattcaaca caccttaaaa tcgatttaaa
     3061 tagttctttt tgatagcata atttatatga tataataaaa aaatagaagt gtattcgcag
     3121 tacacttcta tagttataac taagcattct catgagcggg agtgcttttt tcatttctcc
     3181 aaacaacatt atttttttca tcaataatta tcaaatcaat ttcaatatct tctaaaattt
     3241 ctgttgcagt acaaattaga ttatctaagt caaaacttcg agttatctct agttgtttgt
     3301 tatttacttc tctttttagt atataagttt taaaatacat ttatatcacc ccttgtattt
     3361 actctttttt ctctaaaaat atattgataa gtaaatatgc aacaaataaa aaaatttcaa
     3421 tgacacatag tgttatagct ataactagaa gtgattgatt tttacatgca ctataagcta
     3481 tgatgaaaag aaatgtaaaa gtaaataatg tataattcat aattttaact aagatatgac
     3541 ttgttttcat tgttaagtac aagtctcttt catctgtact atcgtgtaat tcttcaacaa
     3601 tgctttttct tgaaaaagca ttacaaaaat taaagattgc tattacaatt aaaagaaatg
     3661 atgaaattag gaatctttta tcttttaaaa tgcaataaat aactaaacta gcacaacata
     3721 acatacaaac tataataccc actataaaac ttcgtttact ctttactttc atgtttttta
     3781 tcctccattt ctttattttc ttttaaacaa catagttctt caatcgttgt accaaacact
     3841 tgtgccatac gataggcaag cataagagaa gggctatatt gctctttttc aatagaaata
     3901 attgttctgt ttgatacatg gactaaatca gcgagttgtt gctgtgttag acccatattt
     3961 gttcgaaatt ctcgtacttt tgttttcatt ccataacctc tttctatatg aagctaactt
     4021 catgtgaagt taacttcata gtatcctaaa atgagtaaaa tgtcaatctc attagataag
     4081 tattataaaa cctaaaagaa taatatggta aaaattggat ggaattattt accttaattc
     4141 tcttgtttgt aaaactttat tgatatagaa tttaacatat acataaatcg gcaaaggggc
     4201 gcgaattatg aaaattagta aattaccaga agtggaatta aaagttatga gatatatttg
     4261 tgaagctaac aaggtattaa cttctaggga attagttgct gcaatggaag aaaaatatga
     4321 gtggaatgaa tcaactacat ttacagtttt gaaaaggtta gagcgaaggg agtttttaag
     4381 tacagagaaa ataggtaaac ttacacatta taatatacta gtaaaggaga aaaaatatct
     4441 aaggtttgaa acaaaggaat ttttgaagaa catacataaa aattcaattt caagtttaat
     4501 gtcagcgtta catggtaaga cgacgaagtg gatgaagata aattaagtga actcgaagaa
     4561 tattttaaga atttgaaata agaaaacgac aaattgatac ataataaata aaatgaaggt
     4621 atgaaattat aactttttct accttcattt tgtttattat tctgaacatg ttaagaaaat
     4681 gaaataagtt tgtattttag ttatataaat tttaatagaa tatgtacagt atatagtaga
     4741 tagaatgtat aaaaatagaa tttaaataag tagctattat tgcagtgaaa tgaatgtttc
     4801 taagtatatt tgggtggaag aatggtggaa gaaaattagt gaaatgtaat tcttccacca
     4861 ttcttccacc caaaaaataa aaactgttca ataagaatta atatacatca attcagctga
     4921 atgcaatcaa aatacttaaa tgaaagtaat ctgaaaacaa cataattcaa atcaatttat
     4981 tcaaataaac ctcaatttat cttaaatctt aagaaatatt taagaattag gataatattt
     5041 tcttaagatt tatattttat tatatagtta taagggaaag ttacaaaaat gtaagccaaa
     5101 gtaatataac aatttagtca ttgttgagaa agggagtgaa agatattgta taatatagat
     5161 aagtattatt atacaataga ggaagtgaaa atatgtacaa tatattagta gtagacgatg
     5221 ataaagaaat tgttgattcg atagaaatat atcttaaatc agaaggattt aaaatatata
     5281 aagcatatga tggaatgaaa gctttggaaa taataacaga gaatgacatt catctaatac
     5341 taatggatat aatgatgcct aaattagatg gaatcaaagc aactgtaaaa atacgagaag
     5401 aaagaaatat tccaataatt ttaatttcag caaaaagtga agatacagat aaaataatag
     5461 gattaaatat tggagctgat gattatataa caaagccatt taatctatta gagcttatag
     5521 ctagggttaa atcaaactta agacgatatg taactttagg taattatgaa gatacatgta
     5581 aagaaatttt aaaaagtgga gctttggagt taaatacact aacaaaagaa gttaaaattg
     5641 atggtgaaaa cataaaaatg actccaattg agtataaaat aattgaactt cttttagaaa
     5701 ataaaggacg agttttctca atagatgaga tatacgaaaa agtatggaat gaggaaagtt
     5761 ttaattcaga aaatacagta gcagtacata tcagacgaat aagagaaaag attgaaataa
     5821 atccaaaaga accaagattt ttaaaggtgg tgtggggagt tggttataag attgaaaaat
     5881 tttagtggaa aaattataaa agaaaagagt ttaatattta attgcatttt gattttagtc
     5941 atttttacat ttacacaaat gttaggaatt ttaatatgtt ttaatttttt ctctgagagt
     6001 ttaatttact ctatggggat tatgcttttc ttaaacttta ttttatataa aatactgaca
     6061 atgtagatga ggtgggcaac ttggagaaat atagagtatt aaagttagtt tcattaatca
     6121 taatatctat ctcatttcca ttaactatat tgttggtgac aataggactt gctgagccta
     6181 aatacaatat acaaaaaact tctacaaaga gtgggatttt tgatatatct gatgattttt
     6241 atgatagtaa tatatttgac gaaggaacaa tggcaagtct attacccaag tttaagctat
     6301 ctgtaggtgg taaattaact agtaaagaaa aaggtaaatt ccaacaagaa ggtaaaagta
     6361 tagatttaag tagtagtgat tctgagtatg ataaaatcat gattaatgaa caagcttctg
     6421 aagaatattt aagttatcta aaaaatataa aagtgtatgt tattaataca tacacaggag
     6481 tattttatac aaatacgtca tatgctagtt tatatgattt taaacaaaaa actaagagct
     6541 attgtaatgt agagataata aataagatag gaaagagctc atatattaaa acaataaatg
     6601 gagaaaaatt tgaactgaat aatctgagtc tggaactaaa tgaagtagat gaaggttttg
     6661 aggcatatgt atcttttcca gaagagccaa ctatagaaga tggaatagta tacactaatt
     6721 ttcaaatatt taaacaagct acagaaaaag taagattatt ttttgtagct agtttaagtt
     6781 tagcaattat atgtttatta tctataattt tatatatcaa aataaaaggt gaagttttaa
     6841 aaagaaataa tgtattttta ctaatataca gtaagatacc tatggaattt aatgtaatat
     6901 tagtatctat ttcaattgca attttaacta tatatgctct tgctgtatct tatcatattg
     6961 atgtaattgc attagtttct ttatctttac tgatagtatc aaataatata ttttttataa
     7021 atgtgcaatt gagctattta gaaaataaaa tgtgtatatt taagacaagt attatagtaa
     7081 gagtgatttt atggttaata aaaactgtaa gggaggtcag taacgctata aagaaagtat
     7141 ctttagcaag gaaagttatt gttatagtga taatatcttt agctttaatc atggcaatta
     7201 gcactcgaag tataggtatg ggattactgt tttctatatg tattttttta ggatttacaa
     7261 tatatataac taaaagactt tcatatctta gttacgtaat agaaggtaca gaaagaataa
     7321 aaaagggaga attagattat aagataaaaa ttactgggaa tgataatttt acgtctttag
     7381 ctgaaaatat aaataatatt ggagaaggtc ttgatagagc tatagaagag caagtaaaaa
     7441 gtgaaagaat gaagtctgac cttataacaa atgtatctca tgatttgaaa actccactta
     7501 cttctataat aaattatgta gatttaatta aaaaagaaga atcaatacaa ccagagtata
     7561 taaatgatta tataaatgta cttgagtcaa agtcaaaaag actaaaatta ttgatagaag
     7621 atttatttga agcgagtaga gtaagtagtg gcaatataga attacaaatt agcaagattg
     7681 atttagtgca actattaaga caaagtatag gtgaacttga agaaaaatta tctaaaaata
     7741 atttatattt aaaattaaat gttccaaatg ataaggtgta tatatgggca gatggaagaa
     7801 gaatgtatag agtatttgaa aatcttttat ctaatatagc aaaatattcc ttagaagaaa
     7861 ctagagtcta tattgatgta tatgactatg gtgaaaatgt aaaggtaact atgaaaaata
     7921 tatcttctta tgaattaaat tttgacccaa gtgagattat ggaaagattt aaaagagctg
     7981 atgaatcaag gaatactgaa ggaagtggat tagggcttgc tattgcaaga gatttagtag
     8041 ctttacaagg tggaaaattt tatatagaaa tagatggaga tttatttaaa gcaaatttag
     8101 agtttcaaaa atatgaagaa gaaataacaa atatggaatg agatagtatt taagtatata
     8161 tatttttttt actgtcgaaa gcttttatta taatatatta gaatatttac agtagagaat
     8221 gaagagtaaa aacagagtaa ctttaagtca ctctgttttt tatttaaaat caataatata
     8281 acaacttaaa ttaaaattgt acacatagtt ttaaaataac ttatacaata aaacattatc
     8341 caaatatcac aagataattc caaataaata tatagatatc actcctgtaa taatagaaat
     8401 accaatagat ttaaacttat atgcaacaag aagtacaatc ataaaagata taattttagg
     8461 gttagctata gataaatata gactatctcc attaaaaaat acatctttag cagttaagga
     8521 agtaagtatc gctacaggta taaatttcat gatttttttc aaaaaatcag gcatctcttt
     8581 ttttgaaaaa attaacatag gaagcactct tggtagatat gtaacaatgt acattccaat
     8641 tataataaaa aatatataat tattattcat aagattcctc ctttttacag taagattctt
     8701 ctataaagaa accaattaaa gatgctaaaa ttgatgcaac tattattact aaattgcttt
     8761 tgaataatgc atataaaata acagaaataa tgattgatga tataaatact acaatataaa
     8821 tcttattttt tatttgagaa actattaaag ctataaacat agaagtcaat atgaagccag
     8881 aaatagaact gtctatagat atactttctc ctaaaaatgc tccaataaaa ttagctaaaa
     8941 ctgatgaaat taagcagaag aaattaagat aaatagcatt tctatcagac caatttccag
     9001 cagtaaattt ttcataatta actgcaaaag tttcatctgt tatagtatga caaaatggca
     9061 atataaattt tggactttta ttttttatgt acatgttcaa attagaactc attagaaaat
     9121 gtcttaagtt aactataaat gtagtcaaaa caatagatgt tacacttgca ccagtagaaa
     9181 tcattgaagc tgcaatgaat tgagaacttc ctccaaatac taaagttacc attagtgcta
     9241 tttgaaaagg tgaaagacca gatttttgta atagtattcc tcctactata cctataggta
     9301 tataacctaa gaatatagga attgaagcaa taaagctttc ttttaattgt tgagttcttt
     9361 ccacaataaa tcactccttt tgtattaaat gtattaaagt attcgtaaaa cagaaaaata
     9421 gattaattgt ataattgcaa ttataattaa aaataaattt ggattaatat ataaaatact
     9481 atacaacaaa tagataatct taaacggtta ttaaatttta tctatttgtt attatgatgt
     9541 aataatacat attaatctct ataagttaat tactatctgg tgtaatttta ttttaacaac
     9601 aaaaaaaaat acacacaatt aaaatattgt gtgcaataca attatttttt ctcttctaat
     9661 agtcttttta atacgctcag accagcttta agttcttctg tactttctgt agcacataca
     9721 gctattctta ttgcagaaat tggtttttct tttccaacag caaaacgttc agaagcatag
     9781 acctgtacac cttctttaag tgcttgtatc tcaaattttt ctgccattat tccatcaggt
     9841 agaatcaacc atctaaatat acattcttca tttcccaaaa gattatatcc agataaatat
     9901 tgattaataa tcttgtttct tcttcttgca gatttacggc gtgcattaat taatttatcg
     9961 gcttcacctg atgtaatcat gcgataagca atttctgtta aaaaataaga ttgagataga
    10021 ttaatgttgt ataatgcgct tgataatgcc tctcgatact gtttaggtgt agagatatat
    10081 gctagccgta aactaggtgc aataattttt gataaactcg taatataaat tgtttgattg
    10141 ggcagatagg aagccactgg atttaaatgt gtttcattaa gtaaactatg aatagcatcc
    10201 tcaataacaa ttaaattgta tttagatgca atatttgcaa tcatttttcg tccattttgt
    10261 gacattatat gtgtagttgg attttgataa tctggtatta tgtatagacc tttaatattt
    10321 tcatttttac aagcatataa tagtccttct tcactaatct cattatcttc ttgtttaatt
    10381 ggaattagtt gaatcccaag cattttagct gctgtcttta ttccaggata agttaatggg
    10441 tctacaccta ttctatctcc atgttgaaac aaaccagcta aaatagcaac aattgcattt
    10501 tgtccaccac ttgcaggaag taagctatct gatgtagttt caagcccagc tttataaatt
    10561 aatttggcaa tagcttcttt ttgccattta gcaccatctc tttgtccata ttggaatata
    10621 gttttaaaat ctatttcctt aattatgtgt ttaaacaaag tattcatttc ttctagtgtg
    10681 aaatctggat tcattgtgcc catttcaata aatgtaattt tattattact ggacatcaag
    10741 aatagatttg aacgtgtatc ataagataca aaagttccac ttcctgtaac tccacttatt
    10801 agaccttttt tttcacaaat tttaaaagct ctagagatag tactcacatt aacatctaag
    10861 aaatctgcca attcacgttg gggtggtaat ttagtacctg gtaataaaaa tccattgttg
    10921 atatcttgtt ctagttgttc tgcaagagcc ttatataata tttgcccttt tgaaggtctc
    10981 tttggtttcc agttcatagg ataattttca aaagaattaa ttggcataag ttttcacctc
    11041 acattattaa tttgattttt tctttatcta aaacaataaa ttctaaagat acaaataaaa
    11101 actgatagga aataattcta tcagtttttg tcttttaatt gatttcaaat cttcctataa
    11161 tttttatacc ttctttatca taaagaggga ttgttttttt aaatatatta aaatttcttt
    11221 ttcttgtata taaaacagct tcttctggtg tctttggttg attatcacaa tcgtacaaat
    11281 ctcttttttt tacgtagccg acttttttac ctctacctat tgtttgtata agttctggtt
    11341 caatggaatt tctatttgag tctattatat gtgtaccata ggtttctcca tttttattat
    11401 aattaatctt accaatagta tattctacat cttcattttg tttaaaattg gagttgatag
    11461 aaaatattga ccctattatt ataaaggtta ataaaaactt aagacctaaa ttaattttct
    11521 ttttatcttg attaaacata gaatctaacc tcttttttaa aataatattt tttttattta
    11581 gaaactgaga tacgaatgat gaatacttca aagttttttg atactttatt gtatctaata
    11641 ttatatatgc atactcttta atttcactcg tggtacactt gtcaatcaca atttcatcac
    11701 aagataattc acataattca tgaaaatatt tttttaataa gtataaaatt ggattgaacc
    11761 aatatatgat acaaattgta ctaattagaa gcttaaataa gttatctttt cttttataat
    11821 gaattaattc atgtttaaag atgaatctta actctttatt attgtacttt ttttctggaa
    11881 ttattatttt acagcgtgtt aaacctataa tggcagggga ataaatacct ttaaccttat
    11941 atatctgaag ttttttattt atacttagtt cttttgcttg ttcatctaag atactagtaa
    12001 tatctatttc taaaatttct tttttaaaat tttctatgta attataaaat ttaaaatttg
    12061 ttcttaaata gtaaaaagag attgctataa ttcctaatat ccagatgtac ataaatatat
    12121 ctaaagtgat gccctggtca tatggtatat aattatcgat attatgttta tagatattaa
    12181 tagtagtatt attgatattt aatatattta aatttatttt agatataaac atcattctga
    12241 ctactattaa aagatatata aaataattaa acttaaaagt atatttgctt atctttttag
    12301 taaataaaat gaaaaaaaga attagtggac ttatgtaaat attaaattta ataacttcta
    12361 taaataattc cataaaatac gtctcctatt ttcttttttt tagccattgt tcaagttctt
    12421 ttatgtcatc atctgatatt tcatttccac aatctaatga tgatataaag ctatgaatag
    12481 aatttttatg tataagctct aaaaaatcct ttgtttcaaa ttttagatat tcctcatgtt
    12541 taactttaat agtgtataaa gtatttctac catctttttc aaattctaaa aaacctttat
    12601 cacttaatct agaaagtact ttaccagtag taccttttgt ccatccatga gaaatttcca
    12661 tataattagc tacttctctg gctggtattt tatctatgcc tttatcccat atgaaattca
    12721 taactaacaa ctcggatttt ggtatttttt tcaatataat cactcacctt taacttgatt
    12781 atattagaca aatgtctaat agtcaatata atatatcatc atgtataaat aatctttata
    12841 ttattttatg cttgagaact aagtagtata gatttataga taaaaaagat attgagagtt
    12901 ttatggaaga ggggaatata ttttctatta gagataagaa tatgacatat attttttatt
    12961 gatttgtaca aaaatactat atagtgaata aattaatatc ttttctaaat tagaagagga
    13021 gaatcttatt agataaagat tatcctcttt attgaaagtt taagggatat tagagattat
    13081 taatttttct ctcttttttt aactaaaagc aataatacat aaaattatta ttgctaatga
    13141 tactcttaat gtgatatata gtcatagtgt cacatgttta tcaatagttt tttcagtaat
    13201 tattgtaacg aatagtagga ctcataaaat acttagaaat atgtttttag ataaatttta
    13261 aatatataat ctaacttata tctataaatt aacactatta ttctccaatt ccatttctag
    13321 tttttttata aatttattaa attcttctgg ttgccttttt ccaaacaata ctcttacaag
    13381 agctgaattg atttttccaa atatattcct cttgctctca ctttcaataa aaataagttt
    13441 tgtattttct aagtcaatat gtactaattc atatctagta atagtacttt ctcttttatt
    13501 gcttgttttt atctcatata ctctattttt ttcgaaatta gttatttcaa ccttaaatct
    13561 tttattattt ttttgctgta caaatgttcc tactgctttt ttctcattaa aattaggaaa
    13621 atttagtctt gcagattttg taaatatatt aaatatgtct tttgcagaat attttaataa
    13681 aacttcagtt ttaaatgtat tcatatcgtt ttcccttctg tatataaatt taatatttat
    13741 aagttaattt ttaagttaaa atagtataat atgccatatt aaatcatgtt aaaactattt
    13801 atatagctaa aatcttacct atataagtat gtatactatc atataaaaat aaaatcttaa
    13861 aatagaaagg gttaaaaaca cagtttatta taatttttat tgttgagtag atacgtacta
    13921 ttatatatga ttgagcaagt ttttcaatca taaatttata aagtattttg cattaaaatt
    13981 taaacaaaga attaaattat ttaagattat gaataactaa tacatttagt aaattactaa
    14041 atatacaaaa tgtaaatact tatcaaaatg tataaatact tatgacatct agttacttac
    14101 agggtttaag tagaaaaaaa tatcaaagta agtatggcat gatagttgct tatatattta
    14161 tcaagaaagg agttattaag catggagttg agagataaac ttgtaaacat cataaataca
    14221 gaaaataaaa aagatccatt aacagatgtt caaatagcaa agtttttaag tacaactaga
    14281 gagaacataa ctaatttgag aaaagaactt aatataagta attcaaggca aagaagatat
    14341 ccttatttaa aatcagcaat ttcggcaata ttacaaaaga ataagaatat ttctatatca
    14401 gaaattacaa gggaattgat gacagaaggc tttaatatat ctagaagagt tgtggaggaa
    14461 cttttaccta aagaaagttt agaaatggat gtagtagagg aatctgaaga agaatcgaat
    14521 gacccatttg aaactctgat aggtaataaa gggagtctta gaaatgctgt agagcaggct
    14581 aaatctgcta tattgtatcc accaaaaggg ttaccaacgt tgattattgg ggaaagtgga
    14641 gttggtaaga gtttattttc tagacatatg tatgagtttg caaagcaaaa aaagatagta
    14701 aaagagagct ccaattttgt tgtatttaac tgtgctgatt atagtgacaa tccacaatta
    14761 ttattatctt tgttatttgg atataaaaaa ggtgcattta caggtgctga atatgataca
    14821 ccaggtcttg tagaagaagc tgatgaagga gttttatttt tggatgaaat acatagattg
    14881 cctccaaaag gtcaagaaat actattttct atcttagata ggggaaagtt taggagatta
    14941 ggtgaaacta atgctgaaag aaaagtaagt attatgttga ttggggcaac tactgaaaat
    15001 gtagagacta atttattatt aacattcaga agaaggatac caatgctaat aactttgcca
    15061 ccattacatg atagattact aaaagagaaa atagacctta tatacaatat ctttcaacaa
    15121 gagtgtaata gaataaatgc aaaaatattt gtagataaaa atgtgattga aatacttgca
    15181 ctaaaaaagt ttagtggaaa tataggacaa ttacaaaata tgattcaggt tctttgtgca
    15241 agagctttta tgaagtttat aaattccaaa gatgaagata gtgaatcgat agtagtagta
    15301 gatataaatg aagttttaaa gcttaaagat tcttttaaag atactgcctt tcaagagatt
    15361 gaatatacag agataagaaa atatttgaaa aatgctatat ttataccatt taatttagaa
    15421 gaatcatcaa taaaaggaag tcttttaagt gatgaatata tattaccaga ggacatatac
    15481 aaaacaattg aaaagaaata ttatgaccta aaatccctag acattgaaga tatagatata
    15541 gagaatattt tatggacttt tattttaaat agatttgctg acttaaagtt taatctcgat
    15601 agtaatgaag aaattttttc aatgagtgat ttaaatagtt ttgtaagtga tagtttagtt
    15661 aaactggtaa aagaacttat gaatgatata gttgaaaaaa atatgaattt agaagtaaat
    15721 aaaaatatgt tcaaatatct agcaatacac ttagaagaag ctataaaaag aattaagcta
    15781 aatcaaaaga taataaatgt aaatttagaa aaaataaaga ttgacttttc aaaagaatat
    15841 gaaattagta aaagttttgc aataaaaatt gaggaatcaa ttggtattaa aatttcagat
    15901 gatgaaattg gatttataac gctctacata aagtctgctc taaaaaatga agtgaaaaaa
    15961 gataaagtag ggttaataat aatttctcat ggacgtatag ctacagagac tgtaaatgta
    16021 gttaaagaac ttttaggtgt aaagtttcct gtggctatag atatgccttt agatgaaaaa
    16081 ccaataaata tatacaataa ggcagtagaa ttgtcaaaaa taatagacca agggaaaggc
    16141 atattgtttt tggtggatat tggttcactt acaaacatag gtcaaatagt aaataagaga
    16201 accaatataa gtactaaaac tattgataga gtagacctcc taatggcact agaagcaact
    16261 agaaaagttt ctatgggaga ggaagaactt gatgaaatat ttttttcttt gctaaaagat
    16321 aggatgggat ataactatga attagaaaaa cacatagata aatcaaatgc aattataaca
    16381 ttatgtctta ctggagaagg aactgctaag tatataagta aaacgttgga agaaaagtat
    16441 gataacacta aatgttatca aatgagtgca ttggatgaaa atttattttg taaaattgaa
    16501 aatctaaaag agacaaacaa tatattagct attgttggga caataaaccc taagatacca
    16561 ggtataaatt ttatacccta taataaagaa cttttcaaaa atttggatat ctatctatca
    16621 aaatcaaaac aacaagatga cagaccagtt aaatcgtatg aaagaatgct tgatgaggat
    16681 ttagtgattt ttgaaccaga tatatatttt aaaaaggatt tattagaata tgtatgttca
    16741 attcttataa ataaagaata tgtagaaaaa gattacttag attctgtttt acatagagaa
    16801 gaaatgcttc caacatattc taaaggagct ataggtgtgc ctcatggaga ttcttctact
    16861 gtaaatagta caaggtttgt ttttgttaaa ctaaagaatc ctattgattg gggtgtaggt
    16921 aatgtaaatt tcatatttat gccagttttt caggctaatg ataaagagat tgttaaaaat
    16981 gttcttgaga tactaaaaga tgcagaattt atgaacaatg ccaataagtg ttttgataaa
    17041 gatgctttta gaaggattat atttgataaa tttaaacatc tgtagccata gcaaaaaaat
    17101 tgagaggagt tagagtaatg aatgtagatt taatatcatt gggtttagaa tctaatgatt
    17161 atgaaagtgt tattgaagaa ttaggaagta taatgtgtaa aaaagaatat gtaaaagaaa
    17221 catacataaa tgctgtcttg gaaagagaaa ggacattacc aacaggtcta gatattggag
    17281 aaatgtgtgt tgctattcca catacagatt caaagcatgt aaatgagtct aatgtagctg
    17341 tagggatatt gaaaaatcct gtaaagttta attcaatgat agacccaaaa gatagacttg
    17401 atgtagaact tgtattttta ttagcagtaa agaacccaga ttcacaagta aaactgttaa
    17461 aggatttaat gtcagttttt caaaatataa agttattaaa aaatataaaa aacgcatcaa
    17521 caaaagaaga agtagctaaa ttattggact ttatagaaat ttaatgtagg agaattttat
    17581 aaataaaaaa ttaaaattta aacaatcaaa gtaagtatta tttttttaat aggtttaata
    17641 ttatataaaa taaaaattta gagtgaaaaa ttaggaggaa ataattatga aacaatttaa
    17701 tgtattatca gtttgtggtt cagggacagt tacatcatct atggtagcag gtaaattaaa
    17761 agaagtacta ggtaataagg ggatttctat tactacaaca gaagctagac caacagaagc
    17821 actaaattta gcacaatcag gaagatttga ctttataaca tttacgagtc cacttcaaac
    17881 aggcgattat ggaataccaa ctataaatgc atttgcttgc ctaactggta taggggaaga
    17941 ggcattcttt gaagaagttt tgactgttat tgaagggata gataagtaag ttttggagac
    18001 ttgaatttat agtatttaaa tcaatgattt agatactata ataagctaat attaactaaa
    18061 tatttgtgga aaaaacattt tatatgttgt cataaattaa aaaattataa aaatagtcac
    18121 ttaagtatta aattaagctt ataaatattt ataagtagga gggaaaaaga tgttagaatt
    18181 tatgaaatct ataatcgata catttggttc tgcgattata gttccaatta taatattcat
    18241 aatagcaaag atatttaaag taactactaa gaaatcgttt ctttctgctg tgtatgcagg
    18301 agttgcttta caaggtttta cactgatttt aaattcattt acaccaataa taacaccagt
    18361 tatcaatagg atggttgaga gtacaggagt aaacctacca gtttttgatg ttggttggca
    18421 agcaacatca ttggttgcat tttcaacaag tgcaggtatg atatatttag gtcttggtat
    18481 attattacaa acaattttat ttttgataaa atggacagac gtgtttcaac catcagattt
    18541 atggaataac tattcttata tggtatgggg agcaatggtt ataggagtaa caggaaattt
    18601 tcctttaggt atagcatgta tggttttatt aaacctatat agtttattaa tatcagagtt
    18661 agttgcaaag agatggtcta gttactatag atatcctaat tgtacaataa tagctatgca
    18721 taatgttgag gcttctgtgt ttgcagtatt tgcagaccct atatacaata aattgggatt
    18781 aaataaaata aaattaaatc caaaagaatt agagaagaaa ttagggtttt taggtgaacc
    18841 aattacttta ggtctttttt taggtatgtt tataggtata ttaggtaata tgacgagaat
    18901 aaatactatg gaagcttggg gagaaataat gaaagtaggt atatctacaa gtgcagtgat
    18961 ggcaattttc cctaaagtag caagtatgtt tgctcaagca tttgcaccta taacagaagc
    19021 agctagaaag attatgcaaa aagctggaaa ccgtgagtgg tacatagcag taaatgatgc
    19081 tgttggatat ggtgaacctg caactttaat atcaggtctt atattaattc caataatgct
    19141 tgtaatagct atggtacttc ctggtaataa ggtattacca gttgtggatt tattggcaat
    19201 tccatatatg gttcaaggtt tagttgccat acataatggt aatataccaa aagtattagt
    19261 ttcaggtata atttggtttg gattaggatt atatgtttgt acatctacag caccattatt
    19321 tacagatatg gctacaaata taggtgtagc tatacctgca ggagcaatgt taataacaag
    19381 ttttaatata ctaggaaaac ctttgatggg attagttttc tttgcatttc taagtgcaaa
    19441 tccaatttat ataggtcttt cagttgtaat ttactttgtt ctatgggtat tgtttagaaa
    19501 gaacaaaaca agtattcttg attatttaga aaaacaagca ctcaaaaatg tagaagaaga
    19561 gcctgtagca gtttaagttt ataaaaatga aataagaata attaaaggag tttataattg
    19621 attttatata agtatcagat aatacctgag aaatatttaa atgaaatata gacttctttt
    19681 tatttgataa tatttgtaat tataatgcat tgtattttta tagttgagtt ttctgtataa
    19741 cctgctattt aaaacatact cttttatatt tatacagtaa tgtggtttaa ttttataaaa
    19801 tgtaatctct actggtaaaa gactttgtat ataaggcatt tgcctgaata aaccatttat
    19861 cttttgtatg gcatagatat tgctatatag aagtatatag catgaaagga gatatttata
    19921 tgggaaataa aatgagagca tcagtattgt ataatgtagg tgatgtcaga tatgaaatgg
    19981 taaatatacc agaaataaca gatacgcaag tgcttgtaaa tgtaaaatat gttgggatat
    20041 gtggttcaga tttacctagg tctatggtaa gtggtttgag tggaaataca aaatatccat
    20101 tgattttagg gcatgaattt tctggtgaag ttgttaaaat tggagaaaaa gtaaatcata
    20161 ttaatgtagg agatagagta gctgttgcac cattagtacc ttgtagaaaa tgtgattatt
    20221 gtaatgaagg taattttggc ttgtgtgatg attacagtat aattggaaca agagtaaatg
    20281 gagcgtttgc agaatatgta agagttccag aagaacatat tttaaaacta ccagatacat
    20341 tggattatga aactgctgcc ggaattgaac cagcaactat agcttatcat gggatttcaa
    20401 agtctaatat tagagtagga gatagtgtag ttgtgttagg atgtggtcca ataggtcagt
    20461 ttgttataca atgggcaaag gtgtttggtg catctaagat tatagcagtt gatatttttg
    20521 atgaaaaatt agaactttct aaacttctag gagcaaacta tatacttaac tcaaaagaag
    20581 taaatgtaat caaagaaata aaaaaaataa caaatggtgg tgctgatgtt gtaatagaga
    20641 ctgctggtag ccgatttaca caagaacaat ctctatttgt agcaaaaaag agaggaaata
    20701 tagtgtttgt aggtatatca cacacagaat taccacttag tgcagacgct actgagtgta
    20761 tattacgtgg agaacttacc ttgaaaggtt cttggaattc atatacaagc ccttatcctg
    20821 gaagagcatg gactgcaaca ttggatttta tgggaaaagg tgacattatt tttaaaccca
    20881 tgatttcaca taaaataggt cttaatgaag ttggtgactt tttaagtaaa atgagcaaga
    20941 gagaaattaa tttcaataaa atcctagtag aaatataaaa atttaataaa aaattctaaa
    21001 agcaattaaa ttttataact atgacattaa ataaaataaa aataattttc ttaaataaaa
    21061 tataggagga agacaagtgt tagaaaattt aaaagaagaa gtattaaaag caaacttaga
    21121 attacctaag aaaaagctaa ttacttatac ttggggaaat gtaagtggga tagatagaga
    21181 aaaaggatta gtggtgataa aaccaagtgg tgtagagtat agtaatatga ctgtagaaga
    21241 tatggttgta gttgatttag agggaaatat agttgatggc aaattaagac cttcttcaga
    21301 tactccgact catctagttt tatataaaga gtttgaagaa ttggggggaa tagtacatac
    21361 acattcaagt tgggcaacaa tttgggctca aataggaaaa tctataccat cttgtggtac
    21421 tactcatgca gattattttt atggaagtat accatgtacc agaaaaatga ctagagaaga
    21481 aatttgcaat gaatacgaaa aggaaactgg aaatgtaatc attgaagaat ttatgggaag
    21541 aaatccaatt cattgtccag gaataattgt aaatgaccac ggacctttta catggggaaa
    21601 agatgcaaat gaggctgtac acaatgcagt agttttagaa gaagtcgcaa agatggctta
    21661 ttatacagag ttaatgagtc ctgataatat tatggataag gttcttatga ataaacattt
    21721 ttcaagaaaa catggaaaaa atgcatacta tggtcaaaaa tgattatctg gaggtgaatt
    21781 atgctagact ctttaaaagg taaaattgtg gaaatagcaa ttaaagcaga gcattatggt
    21841 ttatgtaaag aaaagactgg taattttagt attagagata aggatactgg atatatactt
    21901 ataaccccat caggtatagg aagagaagaa ttaaaagttg aacatatttg tgtattggat
    21961 ttggatggaa atgtaataga agttgagaaa ggtattaagc caagtagtga ggtattgatg
    22021 catattgaaa tatacaaaac aagagaaaat ataaatgcca tatcacatac tcattcttta
    22081 tatgcaacag cattttcagt agcaaagaaa ccaattatac caattgtata tgaatcagtt
    22141 aattatggcg gttatgtaga tattgctcca tacgaaagac caggaacttt aaaattagct
    22201 aagagtgttt caaaattact gatagataca gatgcatgct tattagaaag acatgggttg
    22261 acaactgtag gtaatgattt agacgaagca ttattaaaat caagatatgt ggaagaggta
    22321 gcagaaatat actataggtc tttagtatta aatcaattta aagaacttga agtagtagat
    22381 gttgatgagt ttaaatcttg gaaataccca gaagaaataa agttttaatc taaataattt
    22441 tcattgaagt ggttaattaa aatatatgta ttatttatat caattactat gttttattat
    22501 gttaattacc gtattttgca aatatattta ttacattttt tcaaaaaaat atagaatccg
    22561 aaagccatat aaaattgact tgggattcta tactttttat ttatgcattt ttctttatct
    22621 gattttctgg agaatttata tgttcaaaat attttttagt ttcagatact attataggtg
    22681 ataatgcaag taaagctata aggttaggta ttgccataag cccatttaca atatcagcaa
    22741 ttatccaaac aacttctaac tttaagaaag cacctaataa caccatagcc acaaatacag
    22801 ttctataccc attcatgcct tttacaccaa acagaaattc aaaacatctt tctccataat
    22861 aactccatcc caaaattgta gtaaatgcaa ataatgttaa actaactgta agtaatattg
    22921 gtccaaatgt aggaattgct ccgttaaaag ctgcttgtgt cataacagct ccatttaggt
    22981 ctgaacacca cactcctgaa ataacaagag agaatccagt aagagtacag attataatag
    23041 tatctataaa agtacctgtc atagatataa gaccttgttc cgctggccat tcagttttag
    23101 cagcagctgc agctattgga gcactaccta gaccagactc atttgaaaat acaccacgag
    23161 cgataccatt tctaattgcc agtgacatag ttgctcctaa aaaaccacca gtagcagcag
    23221 taggtgtaaa tgcactttta attattaaca taaaagtttc agggatttta ttccaaaaag
    23281 atattaaaat gattccacag attacaacat atataactgc cataaaaggt actattttag
    23341 tagctacatt agatatactt ttaagtcctc caaatacaac taaagctaca aatactgcta
    23401 atacaacccc tgtaattcta gggtctatcc cgaaactatt atttattgca tctgttattg
    23461 aatttacttg agtaaaagta ccaattccta aaagtgcaac tagtatacca cttatagcga
    23521 aaaatattgc aagaggtctc catttttctc ccataccatt tactatgtaa tacattggcc
    23581 caccagacac ttggccattt ttatctttag ttctgtattt tattgcaaga acaccttctg
    23641 aatacttagt agccattcca aagaatgctg ctatccacat ccaaaaaagt gcaccaggtc
    23701 caccagcttt gatagctgta gcaacaccaa caatattacc agtaccaact gtagcagcta
    23761 gagcagtaca taaagctgca aaacttgaaa catcaccact acctttgttt tcagcagaga
    23821 atattaactt aagagctctt ggcagtttag ttatttgaac aactccaagc ttaacagtaa
    23881 gtagtatacc agtaccaact aatagtacca gtaggggtgg tccccaaata aaagcatcaa
    23941 ctttgtttaa aatatcaatt agattcataa aaacactccc tcattttttt tgctttacat
    24001 aatcaataga atttttaatg aagtaattga caggaaataa gtataattta ttaataattt
    24061 ctagtgtaat aaaaaaagct aaatctaaaa aagattcagc tctggatgta cactaattag
    24121 caaccaaaat aaaagtatta gtaaatactg tttttggtag ataatccctg tccttttgcc
    24181 tgagagattg agcataaaag ccttgcccct tcggcgccca taatgggtct ctccagagtt
    24241 ccgtaaattt tacagtccta cttttaaaag tacctgagag tgttactcct tcggtgtgct
    24301 atatagcaac tcttctataa aatcttaacc ggatattgat ttgtcatagc ttattgtatt
    24361 aataatatta atataagttt ttatgttttg tcaactaaaa aattaaaaaa caaagaaaaa
    24421 atataaaaat gtaagcctat ttacgaatta taaacttaga aagatgagta atatacgtga
    24481 aaatgaattt tgtaatacac atacaatgaa gtgtaaaata agttttaaat aaaaaaataa
    24541 taaaatctta aataattaat tagatatgat taaattatgg taatattata gttacgatat
    24601 taagaaaagt tctatttagt tagattttaa gcgtaatatg agattatgta tagagaaagg
    24661 atgtattttt agatgggaaa aatattagtg ctagcagaaa aaccttctgt tggaagagat
    24721 atagcaaaag ttttagggtc aaaaaatgaa aaaaatggtt atatagaggg gccaaagtat
    24781 gtgataactt gggcactagg tcatttggtt acacttgctg accccgaaag ttatggagaa
    24841 agatataaat catggagctt agaagacctg ccaatacttc ccaagcacct taagactgtt
    24901 gtaataaaaa agagtggaaa gcagtttaat acagttaaat cgcaaatgaa tagaaatgat
    24961 atagatgaaa tagttatagc aacagatgca ggtcgtgaag gagaacttgt agcaaggtgg
    25021 ataatagaaa aatcacaggt aaaaaaacct ataaaacgtc tttggatttc ttcaagtaca
    25081 gacaaagcaa taaaagacgg atttgcaaaa ttaaaaagtg gaaaagaata tgaaaatttg
    25141 tattactcag caatagcacg agcagaagct gattggatta ttggaataaa tgcaaccaga
    25201 gctttgacaa caaagtacaa tgcacagctt tcttgtggaa gagtacaaac tcctactctt
    25261 gcaatgttgc ttaaaagaga agaagaaata agaaatttca aacctaaaga gtattatgga
    25321 ttagaattaa ttgctacaaa gggaaattca gatataaaat ttatttggaa tgataaaaac
    25381 aataattctt caacttttag taaagaaaag atagaatcca cattaaaaaa agtaaaaggt
    25441 gtagacataa aaatatctga agtaaacaag tcatataaga aaaaatattc acctgcactc
    25501 tatgatttaa cagaattaca aagagatgca aataaaatgt ttggattttc agcaaaagaa
    25561 actttatcta taatgcaaaa actgtatgaa catcataaag tacttactta tcctagaact
    25621 gattctagat atttaacatc agatattgtt ggaacattaa aagatagaat aaaagctgta
    25681 aatattagtg attattcaaa gatttgtaat agattattaa aaagcaatat tatagctaat
    25741 aaatcgtttg ttgacaattc aaaggtaaca gaccaccatg caataatacc aacagaacag
    25801 aaggtattca tgagtgattt tagtgataaa gagcgaaaaa tatataatct tgtagtaaaa
    25861 agatttttag cagtactatc tcctcctttt gaatatgagc agacaactat aagtgcaact
    25921 gtagaaggag aaatatttaa ggctaaggga aacaaagtaa taaatttagg ttggaaagaa
    25981 agttataaag atattgaaga tgaagatgag tatgaaagta taccaaatat tttagaaaaa
    26041 gatgtactta aggtcaaggg attaaagata acttcaggaa aaacaaatcc accaccatac
    26101 ttaaatgagg gaacattatt gactgctatg gaaaagaatg gtctagggac agttgctaca
    26161 agagcagata taatagaaaa attattcaat tcatttttaa tggaaaagaa aaataaagat
    26221 atatatataa catcaaaagg aagacaatta ttagatttag ttccagtaga cttaaagaca
    26281 ccagaactta cagcttcatg ggaaaagaaa ttattggata tttcaaaggg aaaacttagt
    26341 aaaaatacat tcataaatga catgaaagat tattcaaaag atattgtact agaagtaaaa
    26401 aatagtgata ataaatttaa acatgataac ttaactaaaa atagatgtcc agaatgtggt
    26461 aaatttatgt tagaggtaaa tggtaaaaaa ggtaagatgt tgatttgtga agatagagag
    26521 tgtaatacta gaaaaactat atcacaagta accaattcaa gatgtcctaa ctgtcataaa
    26581 aaattagaac ttcgtggaga aggtgagggg agactcttca cttgtagttg cggatacaga
    26641 gaaaagttgt cttctttcaa caagagaaag caagaagaaa aacagaaggc atcaaaaaaa
    26701 gatgttaatc aatatttaaa aaatcaaaat aaaaatcaag agacatttaa taatccattt
    26761 gcagaagcat tagctaagct aaaaaacaaa taattttaaa gttattatta tacacaatta
    26821 taactttaac tgtatattag ttatatgtac tgatataata tagtgtatag tttaggcatg
    26881 aaagtagggc tgttaaatgg atttaagtgg catatttaaa tactattgta aagagtgtga
    26941 aaatacatgg aataattcga gtgttgaatt atttgagaat atagaaacgt atagtaaaga
    27001 ttcacaaaaa aagagggaaa aagaattaga taaattgcta aatacaatat cagttcattt
    27061 agagaggtat ccaagtgatg ctgtattgag aaaaatgtgg gtaaaaaagg gcgaggtttt
    27121 cttacaaaag acattggaaa aagaaaatat ttttaagtta gaaaaaatgg atgtagagga
    27181 tagaaaaaaa tttttagaga taacaaaaca gtttattaga gatgctagaa aatttgatga
    27241 tgatttacct ataggtgata ttatgcaagc tatgaggaat gtatggattt caaatgcatt
    27301 acaattatta tttggtaaag aagtatatta ttcaaaagct aactttgcat atagtatgtt
    27361 atatccatat actgataatt atttagacaa tacaaatata gataaaaatg ataagatttt
    27421 atttaataac tggttagaaa aaaggctcct gggagaacac actaaatcta aggattatca
    27481 tgaaagtaaa gtatctcaaa tgatagatta tattgaaagt gtatacccta gagaaaagtt
    27541 tacagaagtt tatgaatcgt tattattaat atttaaaagt caagtaaata gtttaaaaca
    27601 acatggtaag gaaaatcatt tgtgtaaaga agatttatta tccatttcta ttgaaaaagg
    27661 aggttcatcc gttttagtag atggatattt aataagtgga ttgatgacaa aggaagaaat
    27721 agagttttgt ataggatatg gatttttatt acaaatatct gatgatttac aagatataaa
    27781 agaagattta aaatacaacc ataaaactat tattacagag atgtcaaaag agggtacttt
    27841 agataaagtt gtaaataaac taataaattt tactattgag ttaatagata gttttaaaat
    27901 taataataaa aataaatctg taataactat gataaagaat gattgcttaa tgttaatttt
    27961 attttctgta gtttataatg ctgaattttt ttctgtagga tatataaaag aagtagagaa
    28021 atttattcca tatacaatag attattcatt agagattgaa gaaaaaataa aagaaaaatt
    28081 taaaaatata gatgttttaa ataatgaaaa tgaatataaa gaaatgattg atattatttg
    28141 tgcagagtag aaaagaaggg agtgtcttag aatagacttt ttagtttatg aggcactctt
    28201 tttgtataaa atcaaatgta ttttcatcat tttaacaatt aaaaagagct tatccctatt
    28261 tgagaaagcc ctttttaatt taaataaaaa tgtcaaggtt aaactattta aatgcagtaa
    28321 taatcccatt atcatgtaag ttttttatga ttgtagctgc gatagggaat ccaaataatc
    28381 cagctattcc aaatagttga gctccaacaa acatacacat taatgttatt aaaggatata
    28441 ggccaatttg gtgtcctact acctttggtt ctaatatttg tctaacaacg gttataatta
    28501 tgtatagtat taaaagtcct attgctaaat taatatttcc attaatgagt gagataatca
    28561 tccaaggtgt caaaatactt cctgtaccca agactggcaa aatatcaaca agtgctatga
    28621 tgacagatat agtaaatgca ttttcaacct ttaggatagt aagtccaata agtagttcta
    28681 tgaatgtcac tgatagtagt attgcatagg cttttagtag ttttaaaaga gcattaatac
    28741 tgctattttt tatatttatt atcataaatt gacttttttc tggaaattgt tttaagataa
    28801 agtttactat tttttgatag tcaaaagtaa agaaaaaaga agcaattaaa gtaataataa
    28861 gttttaacat aaatgcaggt gttttacttg caatactagc aatagcattg agtgcatttg
    28921 ttgaaataga agctactaaa gacatcatag attgacttat attatcccaa ccaagtatta
    28981 atgctaggtt aacattaggt gtactagcat ctatctttga aaataaagta tttagcgttg
    29041 gttgtatact tgatttatat atttcaggaa gtctaaaaaa tacatcactt acacttgcaa
    29101 atatcttcac accaaagcta actaataaaa atatacacaa cccataaaaa attaaaagta
    29161 ttactataga aataagtgta cgatttaaat ttgtattatt tgtaataagt cttataatag
    29221 gtcttaagat ggatgcaatg ataaaactga ttacaaaagg cattaataat ggcaataaga
    29281 attttaatac aatatataca atacttgtta ttaaaactac atatgtaaat ttaattataa
    29341 aattcttttg cttttggata tccataatat aaaacctcca atgtatttga tattattcta
    29401 aatatggtct tttttacaga aaatatacta ctgtatattg attataaact ataaagctta
    29461 tgtaaagtaa ataaattatg taaaatttag gttaattttg tataaagaga tacttttata
    29521 ttttacaatt aataaccaaa tactaaaaaa tattttaaat aaagaactta aaattgtgat
    29581 aaaattaatt tatagatatt aaaaaaagta taatatatgg tttttaagag gtgctaagat
    29641 gaaaaatttt agagatttag gtgggaacaa aactgaggat ggcagaactg taaagaaggg
    29701 attattttat aggtctgcaa aattatcaaa tctaagtgaa aatgatataa agattttaag
    29761 agagttaaat attaaatata tatttgatta tagaagtgat gaagaagctc gtaaacatcc
    29821 atcaacaata atatcaaata taaaaaatat aagaatacca gcaatgagag agctagaaga
    29881 atcaggagga agttttggtt ctattgaaga tatgattgat ggattgtttg aaaaagatgg
    29941 tgcatttaat atgttaaata atagttacta taatttgcct ataaataatc cgtcatataa
    30001 aaaattagta gaacttataa gagactattc taatttacca atattaaatc attgtacagc
    30061 tggtaaggat agaactggtg tggggagtgc tataattctt atgattttag gggtatcgag
    30121 agagaatata atgaaagatt atctaaaaag taatgatttt gcagataaag agatagaaag
    30181 atttatagaa tataagccta aatttaagga cattccaaaa gaaaatttaa aatatatatt
    30241 tggtgtaaat gaagagtata tgaaaactgc atttagaaga attgatgaag aatacattag
    30301 tgtagaagca tatttatatg gagaatttaa tttaaataaa gaagaaataa gaaaattaag
    30361 aaatcaatat ctagagtaaa aggtgagttt atgagtttaa atataacagc aagacagata
    30421 aatataataa aaatattgtt aaattcaaaa gatacaatta gtggtattgc cttaagtcaa
    30481 gagataggat gttcttcaaa aactatacaa aatgaaataa aggatattaa taaacaactt
    30541 agaaatggta aaattttgtc aataagagga gttggttata aactagaagg aagttttgat
    30601 gaggtaaatc taaatagcaa tctctatgat gatgtagata gagtagaata tataatcaga
    30661 aaaatattaa ccttaagtaa tgaagaaaaa aatactataa aacttgaaga tttagccgat
    30721 tctatgtatg taagtgtttc aacagtaaaa aatgatttaa aagaagtaaa aagaatattg
    30781 gaaaagtatt caatatcagt taaatctaag cataaacaag gtatatgtgt tttggaaagt
    30841 gaagataaga tattaaattg tatagttgac ttaagcaata agagagataa tcaattgagt
    30901 ttaaatgatt ttttaaatga tgatataaag gaaagaaaac tattaataaa aaaattatta
    30961 ttagacatat taaatgaaaa tggattggta ttaactgata tagaatttaa gagtgtgtta
    31021 aataatatat tagttatgtt aagcagacat aagtataatg aaaaagaatt tatagagaat
    31081 tatatagaaa attataggag caaaagaagc tcaattttag aaaatgaaca aaacaaagaa
    31141 attataataa attcaataaa aacattttgt aaaaatttaa aattagctac atcaatagat
    31201 ataagtaatg ataaggtatt tgaagagttt ttatataagc atattagtag tttatgtaaa
    31261 aaaataaagt taggtataaa tcaatcacct ataatggctc aagatataaa aataaaatat
    31321 ccatttgctt ttgaactagc taatatagct aaaaagacaa tagaaaaaga tttgaagata
    31381 gaaattaatg aagatgaagt tgcaaacata gccctacata taggaggagc agttgaaaga
    31441 gcatcttata ataataaaga taaggttttc aaaactataa tagtttgtac ttcaggcata
    31501 ggcacatcaa tgttaataaa agctaaatta gagaatatat ttaaggaaaa attagaaata
    31561 ctaaagatta ttccttcata cttagttgaa tatataaaag ttatagatgt tgattttgta
    31621 atatctactg ttcctattga agtaggagat gtgccagtaa taaatatatc tccaatttta
    31681 agtgagaaag aaattagatt aattgaaaaa tatatagaaa caggaaatat atacctagat
    31741 ttagatataa aaagcctgtt tgatagtgaa ttgtttttta ctgatttggt gtttaaaagg
    31801 aaagaagaag ttatagattt tatggcaagt aaacttgtac aaaagggcta tatagatgag
    31861 gatatgaaaa aatcttactt tgagagagaa aaaatagcaa caacagaaat agggaatatg
    31921 gtaactatac cacatggagc tattggaaaa atttttgata ataaaatagc aattggtata
    31981 ttaaagaagc ctatttcttg ggaaatatca gatgttcgtt taataataat gttagccctt
    32041 gataaagata aaatattaga ttatgaagta atattttcaa aaatatataa aagagtagat
    32101 tctatagcaa aagttataag tatatgtgaa aatagtagtt ttgaaaaatt tgtaaattta
    32161 tttaattaga tgggtagtat tgtatataca cctgtaaatt tggataatat aaaactaaat
    32221 aagataaaaa cgataaattt ctcttttaat taagagaaat tttttgactt tcaaggatat
    32281 taatataaag ttaagatata aacataaagc aaataaataa aaaagaggtg gcaatatgat
    32341 ttatacagtg acattaaatc catcaataga ttatatagtt aagctagatg agctaaagac
    32401 aggaagtaca aatcgtgtaa aagaagaata cgtttatcca ggaggaaaag gtataaatgt
    32461 atctcgcata cttaaggaac ttggaaatga taatacatct ttaggtttta taagtggttt
    32521 tactggagaa tatataataa gaacattgga agaaaaagaa ttgaagacag attttataaa
    32581 gataaaaagt ggtttttcaa gaataaatgt aaaaataaag gcgttaaagg aaactgagat
    32641 taatggacaa ggtccaaata tagatgatga agacattgat actttatata aaaaacttga
    32701 taagctaaat caagatgata ttttaatatt ggcaggaagt ataccatcta ctttagatga
    32761 aaaactatac gaaaatataa tggctagatt agaaaaaaag aatataaaag ttgtagtaga
    32821 tgcaactaaa aatcttcttc ttaatgtttt aaaatacaaa ccttttctaa ttaagcctaa
    32881 taacgacgaa ttagaagaac tatttggtgt taaattaaat tcaattggag acatggtaaa
    32941 atatgctaga aggttaaagg aaatgggagc tataaatgtc ttggtatcaa tgggaaaaga
    33001 tggagcattg ttgattacaa aggaagatga agtgcttata agtgatgtcc caaaaggaaa
    33061 agtaaaaaat tctgtaggag caggtgattc aatggtagca ggatttatat ctgggtattt
    33121 gaatactggg aaatatgatt atgctcttaa attgggagca gcttcaggta gtgcaactgc
    33181 tttttcatat gacttagcca aaagagaata cattgataaa ttggtaaatg aaatatctgt
    33241 aaagaagttt taaaatatta aaaaatatat agaaaggtaa ttaatattta tgaaaattat
    33301 agatttatta gatgaaaagt caattaagtt aaatttaaat tcaaaaacca aatcagaagc
    33361 aatagaagaa ttagtagatt tggtcgcaaa tagtggaaat ttaaatgata aagaaaacta
    33421 caaaaaagca attttggctc gtgaagaaat gagtacaaca ggaattggag aaggtgtagc
    33481 tatacctcat gctaaaaatt cttcagttac taaagcttgt atagcagcag cagtgtcaaa
    33541 agaaggtata gattatgaat cgtttgacgg aagtttatca aatctatttt ttatgatagc
    33601 tgcaccagac ggagctaaca atactcatct tgaagtatta tcaagattat ctacaatact
    33661 tatggatgaa gactttagaa ataaacttat aaattcaagc tctgaaaaag aatttaagga
    33721 aataatagat aaaaaggaaa gagaaaaatt cagtgaagaa tatcaagatg agaaagttac
    33781 tgaaaaaaat ataatagata ctaaagagaa tgatgctaat aagtatccta aggttttagc
    33841 agtaacagca tgtccaactg gaatagcaca tacatttatg gcagctgaaa gtttaaataa
    33901 aatggcagaa aacaaaggtg tatcaataaa agtagaaact aatggttcag caggtgttaa
    33961 aaataagctt acaaaagatg aaatagaaaa tgcaacatgt ataatagtgg cagcagataa
    34021 aaatgttgag atggctagat ttaatggcaa aaaagtcata aaaactaagg tggctgatgg
    34081 tatacacaaa gcggaagaac ttatagacaa ggctgtaaat ggagatgctc caatttacca
    34141 tggaggagat ggaagtcaca acgaatcaaa tgaagaaagt gaaagtggat ttagaaaagt
    34201 atacaaacac ttaatgaatg gtgtatctaa tatgttacca tttgttattg gtggagggat
    34261 acttatagcg atagcctttt tacttgatga ttatactatt aacccttcaa actttggttc
    34321 aaatacacct atagcagcat tttttaaagg aataggagat aaagcttttg gatttatgtt
    34381 acctgtactt gctggatata tagcatactc tatatctgat agaccagcgt ttgttgtagg
    34441 atttgtagga ggtgctctag caggtgatgg tggttcaggc tttttaggtg cactacttgc
    34501 aggttttata gcaggttatt tagtagaagg gcttaagaaa atatttagtg tactaccagc
    34561 ttcattggaa ggaataaaac cagtattgtt atatccttta cttggaacac ttttgatggg
    34621 aattataatg acatttttag taatacctcc agttacagca attaataatg caatggttgg
    34681 atttttaaat ggtttaggtg gaacttcaaa aatattttta ggattagtat taggtggaat
    34741 gatggctgtg gatatgggtg gacctgtaaa taaagcagca tatgtatttg gagttgcatc
    34801 acttgaatca gggcagtttg aaataatggc agcagtaatg gctggtggta tggttccgcc
    34861 acttgctata gctcttgcaa ctacattttt taagaataga tttactaaag aagaaagaga
    34921 ttctggtaaa gttaattatg taatgggatt atcatttgtt actgaaggag cgataccttt
    34981 tgcagctgga gacccacttc atgttatacc agcttgtgtt ggaggttcag cagtggcagg
    35041 agcacttagt atgttgttca acgcagctct tcgtgcacct catggaggag tatttgttat
    35101 accagtggtt acccatccat ttgcatatat attagctata gctgtaggtg ctttggttgg
    35161 aatgatgctt ttagcattac ttaaaaaacc attaaatcaa gaagtatagc aattaaagga
    35221 tattcaagaa cttaaaatat gatgttttat aaaaattaat atattgctga attattttaa
    35281 aataaggatt ttatgaggct gttatataac gatttgtaat tgttatcttg acagtctttt
    35341 atttttatat aagtaaaata agtgtgtttt gctttatttg tatttaaatt gtttttaagt
    35401 tagaatataa agaaaattat atattatttt aatattcact cgaactagaa aataatattt
    35461 gttgtatttt ttgtatataa aaatatattg taatattaaa aaaataatag taaactgatt
    35521 gcataaaaat gatttttata taaattttaa acagaagaat aaatttctaa cgaaattgga
    35581 tatttcttct gtaaatacat attcaaaaaa agaattataa gagtttagtc agcagtcgtg
    35641 taagtaataa ggactttata aatatataga aatataatga tattaatata accaagcgat
    35701 ttttaattta gctttttatt aagcttattt tttatactat ttataataaa taaactccat
    35761 gatgggaaaa ctattactat ttaatatgta aaggagtatt ttaaatgaat gaatcatatt
    35821 ggtttttaaa ctcaagtcca aaagaatata acaaattagg tgaaaatata aaaacagatt
    35881 gtcttatagt aggtggtgga ataactggat tgacaactgc atatttatta gcaaaagaag
    35941 gtaaaaaagt agtgcttgtt gaggctgata aaataggata tggaacttct ggaaggaata
    36001 ctggtaaggt aacttgtcag catgatatat tttactctaa gatagagaaa aaatatggat
    36061 tagataaagc aaaatcatat tataatgcaa ataatgaagc tttaaattta gttgaacaaa
    36121 taatagaaga aaacaatata aaatgtgatt ttaaaaggga aacttctttt gtatttacag
    36181 aaaaagagga tactataaag aatattaaag atgaatatcg tacatgtaaa aaaataggaa
    36241 taaattgtga gtatcatgaa actatagaaa atattccatt agatataaag ggggctatta
    36301 gttttactaa tcaaggtcaa tttaacccaa agaagtatat tgatggattg gcaaaagtag
    36361 cagtaaattt agggctaaaa atatatgaaa atacaccagt agtagacctt gaaaaaggaa
    36421 aaatatgtag ggttaaaaca agagaagata atataataga agctgagaat gttataattt
    36481 catctcatag tccatggtat gatggattga atttttattt tgcaaaagaa tatgcagagc
    36541 gtgcttattt aatggttgca gttttggaaa ataaattagc agatggtatg tttataagta
    36601 tagatgaccc atcaataact tttagacaat ataatgatgg aagtgaaaat ttactgattt
    36661 ttggaggagg agaccataaa gttggtcagg gaggaactga gaaagaaata tttgatgatt
    36721 tagagcatta tggtaaagaa gtctttaagg taaaagattt taaggggaaa tggtctgctc
    36781 aagataatat gagttttgac aatgttcctt atattggtta tatcaacaaa agagaagaca
    36841 atatttatgt agctacaggg ttctctaaat ggggaattac taatggaact gctgctggaa
    36901 taataataaa agatttaata ataaataata attctgatta taaagatact tttaatccat
    36961 ccagactagg tagctacttt tcaaaagatt ttataaagga aaatgcaaac gtagcaataa
    37021 attatgtaag tggaaaatta aaaataggta gtggagatat gcctaaaaat aatggagaag
    37081 gaaagattgt taatattgat ggaaaaagat atggtgtata taaggatgat aatggagatt
    37141 tttatattgt agacactaca tgtactcatt taggatgtga acttaatttt aacagtgaag
    37201 aaaaaacatg ggactgtcca tgtcatggtt ctagatttga ctataaggga aatatacttg
    37261 aaggaccagc tcttaagcca ttaaaacttt atggacatgg tgataatgat gttaatccta
    37321 agttattata aaattatttt taggaaggta aagtgtatat gaataaactt ttaaagccaa
    37381 taactatact attgtatata gtttatattt tatctgccgt attttttgta gcaaacaaag
    37441 aatatggaag tctaggtcta gtagcaatta gtttagttgg tactttcatt ttgagtttta
    37501 taaataagca aactgaaaga ttattgagta aagaattata tataatgctt gctttattta
    37561 taatgttttc atcattgtta ggtacttgtt ttaattttta tgatataaat tattatgatg
    37621 attttttgca tttatggtca ggtataatat cttgtattgt ggctttttct ataattaaat
    37681 acttttatac acaaagagag ataagtaaaa tgagtaaagt gtttttagtt atatttttat
    37741 ttatgtttag tatgggagta gcgagtttat gggaaatagg tgaattttta atggatactt
    37801 ttgttgggac tactacacag gccggagggt tagaagatac tatgattgat atggtagatg
    37861 ctttaatagg cacaattata actattcctt ttatagtaaa aaaatctaat atatagtttt
    37921 aaatttttta tattaattat aatggattta attaatcatg ttgagtttca aggtctatat
    37981 gattaattaa atccattttt gttatttata attattattg aatatatttt tacatataag
    38041 atataaggtg atagatagaa attgttggat tatgtaaata attaatatat aataccatta
    38101 tgggcaataa atacaaatca aatgataata tagtctattt atgtaaatgt taaattgtat
    38161 cctaagtata atagtaagtt ttttgatagt ggtgtagaaa gtaaaaatct actagcctaa
    38221 attgatgtat ggattagttt aggaacagta attgcatatc ttaagtttga tgtcatgttg
    38281 ggctactaga aataggtcat ctttttcact tgaatatctt ttctttaaac atggggagta
    38341 tcatatcaaa aacatatgaa aattaagtga tttataagaa cagtaatatt ttatatgata
    38401 gtatagaata gtaataaagt attaggagga acattgagtg ttaaaaaagt ggtttggtat
    38461 tgtgaaaaaa agacaaaaaa gtgagtcagt aaaagaagaa ggtgaagtaa tattaaaaaa
    38521 cgaaaaaata ttatctgaag aaaagttgat agatgaagaa ggagttgtag ttaatattga
    38581 taatgaaata ttaactaaag tagaagtagt aaatgatgat aatgaaatag aagaaaaaat
    38641 aatagaagaa gattggttaa ttagtgaaaa taccataaaa ttagatgata aagaagcaat
    38701 tattaatgat aaaaacatag aattatgtaa aaaagaagtt caagttgaag gtgaaaaaat
    38761 agatttaaat aagtttgaag gacttgacca aaatgaaaat tataatctag aaaaaaatgt
    38821 tattgaagaa aaagaagtaa gtgaatgttt gacagaagaa gatttagagt acataaaaga
    38881 aattaaaata aaaagaggaa aaagtataaa agctataaac ttgtatacta aagaagagtg
    38941 ggtttttgac actcatatac agtgtagtaa aaaactcaaa gttccattag ggtacataag
    39001 agaaaattta aaatatggat atatggatta ctttggagat gcaataaatt atttaagtga
    39061 agtattaaat atagatgaat actgcaaaag tgaatggagc tatctcgata atagcaaatc
    39121 tccatctgag atatttaata ttctaaacaa taaaatattt agtataaggc tttctaatga
    39181 aaaaagaaat gaaattttga caaatgataa aattgaagca ttaaaaatga attatagatt
    39241 tgaatgtatt gatgaagaat atgatgaata ttttaaaaaa tataagtcta taatcaaaag
    39301 aggtggaaag aaaaaagttg aattagtaaa taaaaaaggt gacattttag aaatatttaa
    39361 gtctttagaa gaatgtgcca tttatttgca aaaggaaaag aatgaagtta tacaaatgtt
    39421 aaaatatgga gatacaaaag taggaagaaa ctttataagg tatagtttga gaagtattta
    39481 atttcatttt aaattcataa gagtttcatt tctgattcac acatttaata ttattttaat
    39541 gtaaaataat aaaggtgaag tattgtacaa ttaaaattaa ggagggtatt aatgtctgaa
    39601 gaaaaaaatc caaaagaaaa tacattagat gaatctaaaa attcagataa tgtaaattct
    39661 aaaaaagatg atgtgtcaga tgaaaaaaat actgataaca aagttaaaaa aagggaaata
    39721 aagctaaaca acaaaacact taaagctatt gtagcaattg ttgcagtagg agctatatgt
    39781 ttaggtggag gctatgtttt tggcaaagaa gctggaagaa aattgcctgc tacttcaaaa
    39841 cactataata gcagtgaggt agtagctact attggggata aaaaaataac aggtgaaatg
    39901 ttaagaaaga gaatggagcc attattttat ttaaatgcaa aaactactat gactgatgac
    39961 gaaatacgtt catatgaatc aaatatgatt gaaactatga ttacatctga tatattatcc
    40021 tctgaagcag caaaagagaa aataagtata actaatgacc aactagatgc tcagtataat
    40081 aatttaatga gtagtataga atcagcaatg ggaatgacta aagaagagtt tttaaaacag
    40141 tttgatttga ctgaaaaata tataaaagat gatatgaaaa aagagctagt agcatcaaaa
    40201 tatttaaatg aaaaatcaaa agttactgat aaagaagcag agaactatta caataaaaac
    40261 aagagcaatt atttacaagt tagagcttca catattttaa taaaaactgt tgatgataaa
    40321 ggtaagcaag ttagtagtag caaaaaagct gaacttaaga aagaagctga agaaatactt
    40381 aaaaaagccc aagctgggga agattttgct actctagcta aaaaatactc tgaagatagt
    40441 agtgcagaat caggtggaga tttaggtttc tttggtaaag gtcagatggt ggaatctttt
    40501 gaaaaagcag cctttgcatt gaagaaggga gaggtatcta acaaacttgt agaaagtgat
    40561 tatggatatc atataattaa gaaaactgat gaaaaatatc agccatttga agaggtaaaa
    40621 tcagatttag taagcagttt aacatcagaa aaacaaaacc tacttataca aaatctaaaa
    40681 gaaaaatata atgttaaaat tacagataaa tatcaaatga aagctaaaga atagataaag
    40741 tcaatttatt aaaaaaaaga aaaattaact gtatggataa aagctatttt tactctcaat
    40801 atagagagta taaaatagct tttattattt tgcaataaaa tctatttata tatatgaagt
    40861 gacaaagaaa taacatgcaa aaagatatta aaaagaaata tttttaattt gaattttttc
    40921 aataaaaatt tacaaaaatg aaaaaataaa caaaaaagaa ttgaagattt aagttgttat
    40981 ttaaatatat atatattaag attttctgct gaagatacta aaaaaataat atttttcata
    41041 attttaaaaa taataataaa aaaatgaaaa tacaggcgat aatctattga gtaaacatag
    41101 aaaagatgat attataagta tgtgctaaaa tggttaaagc aatattaata ttaaatttaa
    41161 ctataaaaca aaagggggcg tttttttatg tcaagtacag aaagcgtatc taaaaaaagt
    41221 ggtcatccga agagtttttg gcttatttgc atgacaattt tgtgggaaag atttagttat
    41281 tatggtttaa cagctttatt ggtattattt tttacagcaa gtgtagctca aggtggttta
    41341 ggtctttcta ctcaagaagc aacatccatg tttggcttat ttacaggtct tatatatctt
    41401 acaccattag tcggtggctg gttagcagat aaagttttag gtcaacaaaa atgtatttct
    41461 ataggtgcac ttttaatagc aataggagat ttcgtactat ttgcttcatc tacatctatt
    41521 gcaatggttt gggtaggtct atcaataatt attttaggaa atggtttttt taaatcaagt
    41581 tgctcaaata tagttgggga tatatatcct aaaactgatg tgtcaagaaa agatgcagca
    41641 tacagtttat tctatatggc agtaaatgta ggagcattta tagctccaat aatatgtgga
    41701 ttgctttctg ataatgtatt tgcagtaaga ggagcaagtg gagatatagt atcttatgga
    41761 tataagatgg catttttaat ttgtggtata ggcatgatgt taggtatgat tatatttaca
    41821 cttcttgcac caaaattatt aaatgaagtc ggaaaatatc ctgtgactaa aggtaataaa
    41881 ggtgaaaaaa ttgagtatgg accacttact aagttggaga aaaataggat aatagcaatg
    41941 gttattttat ttttatttgt ggtcttattc tggacagcat actatcaaac acaaagttct
    42001 tttatgattt atgtaaggga taatgtaaat agaactctat ttggatttga aatgccagta
    42061 gcatggctta catcactaaa tgctatatta tgtgtggctt tatgcccagt attagctacc
    42121 ctatgggtta aattatctca taccaaaaga ggtgatttct ctattccagt taaaatggga
    42181 ttaggaatga taataatggg tgttgggttt atagttatgg tatttgctac attagctaat
    42241 ggtccagatg gaatggtaaa ggctagtata ttgtttatag tattgactta tatatttaca
    42301 acagtaggtg aattattctt atctcctata ggacttgcaa tgttcaataa attagctcca
    42361 gctaagtatg ctacgttgtc tatgggagcc tggtatctaa caagtttttt tgcaagttta
    42421 ttatcaggaa agattgctgg ttttacagcc acacttggtt ttttacagat atttggagga
    42481 atagcaacag ttttaataat atttggttta atattattgg gaataagaaa tgtattaaca
    42541 agattaatgg ctatggattt actaacaaaa gaaaaataat tcatgacgaa ttattgtaaa
    42601 taaatgaatt actttaaata aaggaagtta catttaaata taaaattaaa tgtaatttcc
    42661 tctttgatta tgaaaaaaag ctttacacaa atagatatta taattaaaat tataattgtg
    42721 ataattagag tgtataagat ttatataaat tatacaaaaa atatttatgt aataaacttt
    42781 acatacttat atatttagtt attcaaacta ttatttcgag gaggtcttgt tgtgaatata
    42841 aaagatagat taagtggatt aagaaaattt atggaagaaa aaaatataga tgcctatatg
    42901 attccatctt ctgataatca ccaaagtgaa tatgtaggag attacttcaa atcaagagaa
    42961 tttatatcag ggtttaatgg ttcagcaggg acggttattg tgactaaaga cgaagctggg
    43021 ttatggacag atggaagata ttttatacag gcagaatctc aattagaagg aagtacaata
    43081 aaattattca aaatgggaca agaaggttgc ccaactacag atgaatattt atataaaaat
    43141 attcctgaag gaggaacttt aggatttgat ggtagagtta tatctgctag agaaggagct
    43201 acattagctg aaaaattatc taaaaaaggt ataaagatag aatatcagta tgatttaata
    43261 gatagtatat ggccagatag acctgcttta tcagatagta aagcattttt attagatgtt
    43321 aaatattgtg gagaaagttt tagctcaaaa ttagctagat taagagaaaa aatgagtgaa
    43381 aaaggtactt ctactcatgt aataactact cttgatgata tagcatggtt attcaatata
    43441 agaggtggag atgttaaata taatccagtt gtactttctt atgcagtaat aactttaaaa
    43501 gaagtttatc tatttgttga tgaaagtaag ttaaatgaag aaatactaaa tgaactagct
    43561 aaggaaaatg ttcaaataaa gccatataat gatgtgtatg aatttgtaaa aaatatagac
    43621 aaaactgaaa aagttttatt agatggaact aagcttagtt atacaattta caataatata
    43681 ccttgtgaag ttgagaaagt tgatgagttc aatccagtaa tgttttttaa agctcaaaaa
    43741 aatgaggtag aattagaaaa tataagaaat tcacatataa aagatggtgt agctttcact
    43801 aaatttatgt actggttaaa gaaaaatgta ggtaagatgg aaatcactga aataagtgct
    43861 actcaaaaat tagaggactt aagaagagag caagaaggtt tctttgagcc aagtttcaat
    43921 acaattgctg catataaaga gcatgcggca atgatgcact atagtgcaac tccagagtca
    43981 aattataaat tagaggcaga aggattattt ttagtagatt caggtggaca atattatgat
    44041 ggaactactg atataactag gactacagtt ttaggaccta taagtgatga attaaaacta
    44101 cactttactt ctgtagcaag aggaatgata aatctttcta aggctaagtt cttgcatggt
    44161 tgtagaggat ataacttaga catactatct agaagttgca tgtggaatat gggaattgat
    44221 tatcaatgtg gaactggaca tggtatagga tttgtgctaa atgttcacga agctccaaat
    44281 ggatttagat ggagagtagt acctgaaaga tttgatagtg cagttcttga agaaggaatg
    44341 gtaactacta atgaaccagg tatatatata gaaggttctc atggtataag aacagagaat
    44401 gaaattgtag ttagaaaagc tgaaaagaat ttctatggtc aatttatgga atttgaagtt
    44461 gttacgttag ctcctattga cttagatggt atagtaccag aattaatgaa taaggatgaa
    44521 aaagattatt taaactggta tcataagtta gtttatgata aaatatcacc tttcttaact
    44581 gatgaagaaa gagaatggtt aaaagtttac actagagcta tatagtttgt actagataca
    44641 ataaaaatcg aggtattata atgcctcgat tttttattgt atattttatt aactttaaaa
    44701 aatttttaat ttgataattc tactaatttt ttattcatta taagtagtat aattccaaat
    44761 atcaataaaa atgatggtat cactatgaag acttgtaaca taccaagttg gtctataata
    44821 gcttgcgtat agccagataa tttatttgct gcaaatttgc ctaaaaacca aacacccatt
    44881 aggaatgaaa tatacttttc aggcgaaagt ttatttacca taccataccc gactggagaa
    44941 aagcaaattt ctcctatact ttggaatgtt aaaaatccaa ctacccaaaa tacacttgct
    45001 ttgtgaattg aattagggtc tgttcctgtt tgtataactg ctactatcat aaacaaaaat
    45061 gctatagcta atagtataaa acctaagctc attttttttg gcacacttaa atcgcctttt
    45121 ttagtttgag ataattttac ccatactaaa gcagagatag gtccaagaat aacacaaagg
    45181 agaccattgt atgaatctat ccatgaagta ggaatttgaa aattgccaac agtaagattt
    45241 atgtgttcct ttgtatagag tgcaatagac atagaggctt ggttatatgc tatccaaaaa
    45301 aatactgtga aaaaagctaa caccaatatt actattattc tttttttctc aatcaaagtt
    45361 aaaggtcttg aagctagcat tttcttatat tctagtgatt ttcttataga ctctctcccg
    45421 ttactagggt cattattcaa aggtttataa aactttctgt ttccaaatat aaagaagaat
    45481 aaacctatta gaaccgtaat tgatgaaaat aaaaatacat atctatatcc atacatactt
    45541 atagataatc cgcttttcat agcaaaccat tcattagcaa ctaaaccgca tattaaaggg
    45601 ccaaataagg tacctagatt agtagccata tacgtaatag agaaagctcc atcttttctt
    45661 gggtcatcat tggtatataa gtttccaacc atagtatgta agtttccttt ataaaaacct
    45721 attcctaatc cagataaaaa tatcatgatg tttatatcca tcttactatt tgctatgtat
    45781 cctagaaaat aaccaattga aaccattagc attccaagta taatacagtt tttgggacct
    45841 aaaaatctat cactgaccca tccaccaata actggagaga aataagtcca tgctaaaaaa
    45901 gatgcaagca ttgatgcgga ttctgctggt gttaacccta aaccaccttt ggagacttgt
    45961 tcagctaaaa acaataataa taccaatttc ataccatagt atgcaagtcc tacaaaggta
    46021 aatattgaac agcagaaata taaatctcta ggttgtttaa gtttttcttg cgtttttaaa
    46081 actgacatat gtcgagaacc tccagataaa tagtttaaca aaattttacc atactatatg
    46141 agtatatgtt tttttcatat agacgtcaac ttgtaagata atttaattaa gtcgaaatat
    46201 atgtaaaaat agtatcattt ttgtgtattc agtaatattt ttttatgata atatatgtta
    46261 ttattatatt aaaatacaaa catatttatg gaaaggatat gccaatttag tagttagatt
    46321 gattgtttgg caggtgggat gagctatgat aagaaagaaa tctgaattac aagtagaagt
    46381 aaaagaaaat ttaaatggtg gtataggaaa ggttaagctt gaaaacataa tacaaaatga
    46441 agagcttaaa ggaaaaggaa gactatttaa aagagtagct ttaccagtag gaagttcaat
    46501 tggtgtgcat gaccatacaa cagattttga agtatattat atactaaagg gaaaaggtaa
    46561 agtatttgat aatggggaat ttgtagaagt aaatgagggt gatgtagtgt atacagctga
    46621 tggcgaaaaa cattctatag aaaatatagg agaagaagat cttgagtttg tagcactagt
    46681 tttatatatg taaaatatgg aggaggagtc atgacaggca agatagaaga aattaaggac
    46741 aagataaata gattttgcaa ctccaattta aatcaagaat acaaagatat aagctttaaa
    46801 attttgcaaa accttttaga taataataaa gagataattc attcttctag agctgatata
    46861 tggtcttcag ctatactaaa tatagtttta gaacaaaatc ttttatacaa taagaagcat
    46921 ccactacata taacaaaaaa agagttttca aaacaaatag gtgtttcttt aaatactata
    46981 aataataaat cgtctttaat aaaagatgtt tgtagtattg actttttaaa tcaagatact
    47041 atagctattt ctaatgtaga attttgggta aaagagacta attccaaatc aaagtctgta
    47101 gatttagatt tagaaaagaa gaaaatacta tataaaagat atattaagct atcacaagat
    47161 gcgaatagtg atattgaatc aattagatat atggaggaag ctgtaaatat aggtaaaagt
    47221 atgattacta aagaagataa agaacttgga ttttggaaag gtttatctac cagagcctat
    47281 atgatagcac ttgaatccct tgctagaaag ttagaaagta ttaataatct aaaggagtcc
    47341 aaaaaagtat tagaatattt aatagaaatt aatcctagtg atgagcaggg aataagatac
    47401 aaattattaa atgtattaat tagattaaat gatagaactt caataaataa attatttgaa
    47461 ctttataaag aagaaaaatc tgctacatgg atgtacagta aagctcttta ttactttaaa
    47521 aataaaagta tgtttttggc aaatgattct attaaggttg ctagaagtaa aaataagtac
    47581 gttggattat atttgttaga ttggcgaaat gcttttggta gagaatttgt tacagaggaa
    47641 gaaaaggcag aagctgtcta ttactatgat gaaaacatag tgatttggaa tgaagttaaa
    47701 ggttctatgg attggctatt aaaaaaaatg ttggaatctt cataaaaaaa actactcctt
    47761 acttttatat aagtcaaagg agtagttttt aatttataca tctagtttta aatcttcagg
    47821 ttttattaaa cctttttttc tcataaattc tgaaatcaac aaagttacaa tagcaggaag
    47881 tataaaatta agtaaaagta taccaaccca catagatata cctccttttc cagcactttg
    47941 catagcagtt actgttccaa attgtccaac caatccacaa gtacccatac cagaaccaat
    48001 aggaatattc tccattttga atattgttgt agataatggt ccaagtaata ttgaagctac
    48061 agtaggtggt atccaaattt tccaattttt tattatatta ggtacttgca acatagatgt
    48121 cccaagacct tgtgccacaa ggccgccaac tccattttct ctaaagctca taacagcaaa
    48181 gcctaccatt tggcaacaac aacctacagt tgctgcacca ccagcaagac cacctaaact
    48241 taacatcata caaatagctg cgctacttat aggtaatgta agagctattc caacaagtgc
    48301 agagactaaa gctcccatta ttataggttg catagttgta gcttgcatta ttatatttcc
    48361 aaatgaagtc ataaaagcag aaacagctgg accaataagt tcagctacaa gtactccaat
    48421 tagtattgtt acagcaggtg taaccaatat atctattttt gtttcttttg aaactaattt
    48481 tccaacctct acagcaaaaa gtgtagcgac aaatgctcca acaggtcctc ctaattcatt
    48541 accacaagct ccaacaagtg cacaagaaaa tagtacaagt ggaggtgctt gaagtccata
    48601 cgcaatagcc actgctatag ctggaccagt aacctgttta gcaagagggc ttataacttc
    48661 agtaaaaaga gaaatattga aattatctcc taatgtattg aaaattgttc caattaaaag
    48721 ggacgaaaaa agaccgagtg ccatataact tagtgcgtca ataagatacc tttgaacaga
    48781 aatttcaata ttttttcttt tagcaaatga tttgaaattt ctttttttat aattgatttc
    48841 caatttaaaa tcctcctcat ataatataag tataatttct ttttaattaa ttatataact
    48901 tttcagctga caagacaaat gttatttcac taaaattaga ctattgtaat agtaagaaat
    48961 taacattaat tttagtttta aattttaaat ttatggttta taattagtat agggatattc
    49021 tgaaatataa taattttcca gtttatccca atatttaact taggtagatt gcttacaaaa
    49081 caaatgatta tatattaggc taaaaggaag tggatagatg atatttgtaa aaaataagaa
    49141 atacagaaaa attgccataa ttatatctat tcctatattg cttgttgcgc agtactacct
    49201 ttttaaattt ggaatactta gaccaatggt aaagggagta gaaattgaaa ttgtagatgg
    49261 ggaatatgtt aaagatatag ataaatatgt agtaaaatta aatgaaacag ttactttgtc
    49321 tacaggtgaa tatattaagg ttccttcgta tgctaaaaat ccaaatattt ggtttaatgt
    49381 attggataac tcagggactt taaaaataga tggaaataaa atgacagcat taaaggttgg
    49441 gtattcttct gtgggtatca tgaaaaattc aagagtatta aaaaaggcta ctataaaagt
    49501 agtagaccca gaggtagaat cactagatat ggagattaat ggggatttaa aacatgttgg
    49561 tgatagtgct actatagaaa gtacaataga agttgattat gataagttta aaaaatcata
    49621 taagccagtt tataagagta gcaatgaaaa tattttaaaa atcaaaggaa ataaagtaag
    49681 tgcagttgga gttggtaaag ctacaatata tgctaagtgt ggaaataaag aaattgagag
    49741 aacatttagg attcaagcta gagttgctga aataaatatg gatgatataa aaatagaagt
    49801 tgaccaaaat gaaaaattga aaccagatat aataacttct ccacctggtt tagaaccacc
    49861 aaaaatatat tatgagttag tagattcaaa attacctgta gaaagagcaa taagtttaag
    49921 tagtaatgga aatgttgtag gtcttagaga aggtaaagat agggtgagaa taacttgtgg
    49981 agataaatct aaagtaataa cagtaacagt agtcaaagaa actataacga atgactatat
    50041 acaaaacttg gttggttcac ataaaatagt aaacaataaa gttattatta aacttgaatg
    50101 ggattatatg aaagatgtct ttgattatga tatatatctt aaagataagt tgtcaggaga
    50161 atcatttaag aaaattaaat ctataactat aaatgaaagt gatttaggta agtctaacaa
    50221 ggtatatgca actatagaag tagatatgaa gggtaatcaa aatatagatt ttgatattta
    50281 tgtcataggg aaaaaggatt cagatacaac taagccaagt aatgtaataa atattaccaa
    50341 tggaaatgga aattcaaata atgataataa tattaaagat atgagggtag aaaatatatc
    50401 agctaatgtt gatagagata ataatgtcat tagagttaac tggagtagta tatctcataa
    50461 ggactgtact tacagtatat atgtaaaaaa taatactaat ggagatggag aatttactct
    50521 atatcaaagt gatatacagg gaaatgagca tactataagt attcctgaag gagatttaaa
    50581 tctagatatt tatgttgttg caaattataa tggaaatagc tctcaaaata gtgatgttat
    50641 aaatgtaaga tagatttgta tacaaattga aagtgttgag tttatttaaa tattaaatta
    50701 agaaaaagga tagtataggg taattatact atcctttttt tgttataata tataggttta
    50761 aaatctctag taatataaat tataaaaagt cttatttaca caaatctata gatattcttt
    50821 ttattaatca atattgtctt aaattgaatt tagtgcagct tctattgcat gtattactgt
    50881 cgtatcaaat agtggaatag aagtgtcatt ttgtttaatt aaaagaccta tttctgtaca
    50941 tcctaatata acagcctctg caccttgttt gccaagctta tctataatag ataagaaagc
    51001 tttttttgaa gattcagata taattcctaa gcaaagttca ttaaatattg tgtcatttac
    51061 tattatacgg tcttcttcat ttggaattaa gacttcaatt ccattattaa taattacatt
    51121 tttataaaaa tcttgttcca ttgtatattt agtacctaat aaggccactt tttttatttc
    51181 tttttccctt aataccgtag cagttacatc tgctatgtga agtaatggaa tatgtacact
    51241 ttcttgtatt ttatctgata ccttatgcat agtattagta cagataacaa taaaatctgc
    51301 ccctgcctct tgtaatttaa ttgcagcatc agctaaaatt ttggcgcttt tttcccaatt
    51361 tccactagat tggcattctt caatttcttg aaaatctaca ctgtaaagta tacatttaga
    51421 agagtgtagt ccacctaatc tttcttttat tactgtatta ataacttgat aatatgtaat
    51481 ggtactttcc caactcatac caccaattaa gcctatagtc ttcatattat acctctctta
    51541 tttatttatt ttgaaatagc tatttacaaa tacaagtata gcatctaaaa tagaagcata
    51601 caataataaa attgtatgga gtacaattat aattaagagg agtaattata tgccaataaa
    51661 ttcttttgaa aactatccta tgacatggaa accaaaatta gataaccgaa aaccaccaat
    51721 atataaaact ttagcaatgt tattagaaga agatattaaa agaggaaatt taaatcctgg
    51781 agataaactg cctccacaac gggaattagc agattttcta gatttaaact taagtacaat
    51841 aacacgagca tttaaacttt gcgaagaaaa gggactaata tgtgcaaaag tgggaaaggg
    51901 aacattcatt tcttctgatg taaatgtaag taatacatta ttatatcaaa cggaatcaaa
    51961 agacataatt gaattaggga cagttcatcc tccatatgag caaaatacat atattattga
    52021 ctttattaaa aatgtactaa aacaaccaga aatggatagg tttttacgat acatgtctcc
    52081 atctggcaca tatatgcaaa aaaagtcaat tgcaaaatgg atagaaagaa ataatgtata
    52141 caccagtgaa gaaaatatat tattatctac aggagggcaa aatgctatat gtgcaacttt
    52201 actaggatta tttaaagctg gtgatagaat tgctacagat tctttaagtt tttctggaat
    52261 taagtcaata gctaaaatga taggtattca attagtccca attcctcaag aaaataatga
    52321 aatatcgatt gaatatcttg aaagttattg taaaaatgaa aatataaaag gcatatatct
    52381 tataccagat tatcataatc caacgacaca tactatgtct gatttatctc gtaaaaagat
    52441 agccaagata gcaaagcaat ataatataat aattattgaa gatgctataa atagcatttt
    52501 tagagacggt atacaaactc ccatattttc tttagctagt gataatacta tatatatttt
    52561 tagtacatct aaatttttat gtgctggtct tagagtagca tttgtagttg ctccaaaacg
    52621 atatatagaa aatttagaaa atgcactata taatatgaat ctaatggttt ctccatttac
    52681 agcagaaata gtacaccgtt tattatattc tcctattata gataaaatta tagaagagaa
    52741 aagagatgca attatagaaa gaaatgaagt tgctgataaa gttttgtcag attataattt
    52801 gattggtgat aagaattgca gttttcgttg gttacttctt cctgatgaat tggatggaaa
    52861 atcatttgaa atttctgcaa aaaatctagg agttcaagta tattgtgctg aacgattttc
    52921 agtaggaaac tctacagttc caaaagcagt tcgtatttgt gtaacagctc caaaagatgt
    52981 agaagaatta gaaaaagggc ttaatataat aaagtcactt cttaagagtt aaatttattt
    53041 tactattatt taattaaata aataaaaagg cggagaaatt tattataata aacctccgct
    53101 tttattattt aatgaaatac tttacttttt attaaaaaat ttaattttaa taatcttgaa
    53161 aatataatcg ttttatggta aaataattct taaaaataga aaaaattaat catttgttaa
    53221 aaaaaatgca taatttattg taatttattg acgaaggttg aaaaatattc ataaatgtgc
    53281 gaaataacag aaaaaatgca aaaattaatt caatttcatt tgttataaaa tctatatggc
    53341 aaaattaaat ctgcctatca gaatgatata aacacatcag aaaggaggac gctatcaaat
    53401 aatacaagta gttaactttg atagcaaaaa attatgaatg aacaaactag aatatcctta
    53461 gagagagctg ctgaattaaa atcaaaaatt gatgattata ttcaggctag aaaaacgatt
    53521 aacagaggtc ttgaaaaaga agaagagata aataaacgaa aacagaaaat attaagtatc
    53581 ttaaatggaa ctgaagagga ttggaataac tacaaatggc aattatcaaa tagaataaca
    53641 gatgtagata ctttatcaaa aattataact ctaactaaaa aagaaaaaga atatataaaa
    53701 gaggttggta ctcaatttag atgggcaata tctccatatt atttgagtct tatagaccca
    53761 gaagatatat gtgacccaat aaaattactg tctataccaa cacatataga gttggaagat
    53821 gaacaagaag atttggaccc aatgggagaa gagtatacaa acccagcagg atgtataact
    53881 agaagatacc cggatagatt aataataaat gtaacaaatg agtgtgctat gtattgtaga
    53941 cactgtcaga gaagaagaaa tattggacaa caagattctc ataagtcaaa agctattatc
    54001 caagaatcta tagactatat cagagaaaat gaagaaataa gagatgtact agtaactggt
    54061 ggagatgctc ttacattaaa agatgattat ttagagtgga ttcttagcca acttaaagag
    54121 ataccacatg ttgattatgt tagattaggt actaggactc ttgttacaat gccacaaaga
    54181 atcacagatg aattttgcaa tatgctaaaa aaatatcacc ctgtatatat aaatactcat
    54241 tttaatcatc caatggaaat aactaaggaa tctaaagaag cttgtgaaaa gttagcaaat
    54301 gcaggagttc cattaggaaa tcaggcagta ttattaaatg gaataaataa tgataaattt
    54361 gtaatgagat gtttaaatca agaattactg aaaataagag taaaacctta ttatatattc
    54421 caaagtaaac atgtaaaggg aacaaaacat ttcaatacat cagtagatga tggtcttgaa
    54481 atcatggagt atttaagagg atatacatca ggaatggcta taccaacata tatagtaaat
    54541 gctccaaaag gaggaggaaa gactcctttg cttcctcaat accttgtatc aaaaggaaca
    54601 gattacgtta tgcttagaac atgggaagga aaagttataa aaatggaaga tgaacctgct
    54661 gtagatataa agaaacttat aaaagaacaa gcacaggatt aaaaaaatat ttaaagttta
    54721 taaaaagaaa caactttaaa ataaaaagaa aatggatgtc aaatttatat caatttgcat
    54781 ccatttttta ttagttattt attattttgt tgttgattaa ctaattcaag atatccactt
    54841 gggtggaagt aatatatctc agaagtattt tcatttacaa agtaaccaat atcaccatct
    54901 gcatctggta aaaatacata accattaaga tttttagctt ttaatgcttc aaaatcacta
    54961 gcatttcctt gatatatgta atcaacttca ttgttgtatt ttactaaaag ttctttagct
    55021 tgttcttgag tcaatttagt attttggctt acaggaacat tcttttgaga atctgcataa
    55081 gaagattcat ttactggtgc agttaataac aaacaagata aaactaataa agatataagt
    55141 gcttttttca tactaaaacc ctctttcatg tttaattata taagattcat tacttaacaa
    55201 tattgtatgt ttcctataat taaatattac cattaaagag aataatatta cagttacaca
    55261 gctgtaactt ttgattacaa aatcgtaatt aaattgtatt tttattccat ttgtatttta
    55321 tcatgtctac gatttacaaa ctcacagaag tatatcttta taacgcccat cacaggagca
    55381 gatagaatca taccaggtat accaaagaat cctccaccaa cagtaactgc taggattgta
    55441 aagaatgggc taagacctag ttgtccacct acgatttttg gctctataaa tgtaacttca
    55501 acttgttgaa ttattattaa gtaaattaaa gaagttaaag caattgttgg attggagaat
    55561 aaattaatta ttacaactgg tgccatacct attactggac caaaatatgg aaccatattc
    55621 atgacaccca taagtgtacc aaataatagt gcatattcag attttaaaaa gtaaagacca
    55681 attccagaaa gtactccaac tataaaagaa tctaaaatct tacctgtaaa gtatttacca
    55741 atatttaaat ttaagctttg acatagttct attataaagt ctccatattt tttacctaag
    55801 gaaatataaa ctactttttt tgtaaacagt aagaattttt ctttttctaa taatatatag
    55861 aaacaaatta taaaacctaa aagaaattgt actataaatt ttccaactga aaatgtagtg
    55921 ctaaatatcc caccaagtga accaataagc aagttactaa atttaggcat tacactcata
    55981 attttgtcac catactcttt taatgtatta gggtcaactg attgtaaact cttacctaag
    56041 tcgaataaaa actgctctgt tttatctatg tatgtaggaa tttgagcaac taaatcagct
    56101 aaactattta ctatggatgg aactgtaaat aatataaagg aaattagtat aactatgagt
    56161 acaccataag taagaagtaa cgaatatatt ctcttaaaat ttaatttact ttctaagaac
    56221 tttactagtg ggttgaatat atatgctaat acaaatgcta ttataaatgg tgttagtagt
    56281 gacattaata aacttatcac tccaaaaaaa tatttgtaat tatcaataac tttaatcaag
    56341 atatatgaaa caactacagt gagtacaata tttagataaa tttttttatc ttgcaaaata
    56401 acacaacctt tcttatattt attaaattta gatatactta aatctaagtt aaagttaata
    56461 tttatagctt attatacaat aaaaagcagt attaatatag tatgattaat atgaaattat
    56521 aaatacgtta aaactttatg tttatagcta aaataataaa aattatttat attgtgttta
    56581 tatataatct aaaatgaaaa aaagtggtgc ctttgattaa actaagtttt tataatt
//
LOCUS       DAEORM030000022        55844 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.022, whole genome shotgun sequence.
ACCESSION   DAEORM030000022 DAEORM030000000
VERSION     DAEORM030000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 55844)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 55844)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 55844)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..55844
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.022"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            983..1822
                     /gene="cdaA"
                     /locus_tag="KRH23_001789"
     CDS             983..1822
                     /gene="cdaA"
                     /locus_tag="KRH23_001789"
                     /EC_number="2.7.7.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004016 - adenylate cyclase activity
                     [Evidence IEA];
                     GO_process: GO:0006171 - cAMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diadenylate cyclase CdaA"
                     /protein_id="HHS5225069.1"
                     /translation="MLDINSFLNGFFNIILRMSIYDLIDISIVAYIFYKIFMFIKDTR
                     AEQVFKGIIFLLLATQLSNTFKLHTVYWISLKALDYGVIAALIIFQPEFRAGLEHIGR
                     AKFNLFGKNVNTSEETLNRNIEEIVEALYSLSRQKIGALIIMERETRISDIINTGTII
                     DAEISRQLLINIFIPNTPLHDGAVVIRDSKVKAAACFLPLTESKDLSKDLGTRHRAGI
                     GVSEVSDCITLIVSEETGGVSIAKAGKLYRDISRERMMNILRSNLKTNTETRSFFKGG
                     IFK"
     gene            1819..3000
                     /locus_tag="KRH23_001790"
     CDS             1819..3000
                     /locus_tag="KRH23_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CdaR family protein"
                     /protein_id="HHS5225070.1"
                     /translation="MINRLKNNTKIKIISFLSAIALWMYVMAVVDPEETKGFEDIPVS
                     ISNMSDLKDKNLVIYPDEKLTADVYIKGSLSKVQSVKKEDIHVYGTIEDPIQGQKEVY
                     LKANIPQGVTLEFKHDVLVVNLEKNIKEKRDIKVEVSGNSKRNINKIELSKEFVDVSG
                     PRTLVKEVKSVRANLDVGNETDDFSKKLQLIPLNSDGTKVEGVTLSSSFVTAKIELLK
                     EKIVPIRVSLNDNKDNDVLKNYKLSKEQVTIKGKKDDIDKISYIKTKPIDLADLANGE
                     EKEVSLEIPEGITLEDSSITIKLNDTKQLSAEFLYNAGDIELRNIPTNMDNPNVISDV
                     DIKVVVESTEDLSKLNKKDISLYIDLSQGPEEDSKYKIKYETTYQFKKINIEPNIVEV
                     E"
     gene            3304..4206
                     /gene="ptb"
                     /locus_tag="KRH23_001791"
     CDS             3304..4206
                     /gene="ptb"
                     /locus_tag="KRH23_001791"
                     /EC_number="2.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050182 - phosphate butyryltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0019605 - butyrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate butyryltransferase"
                     /protein_id="HHS5225071.1"
                     /translation="MRSFEEVIKFAKERGPKTISVACCQDKEVLMAVEMARKEKIANA
                     ILVGDIEKTKEIAKSIDMDIENYELIDIKDLAEASLKSVELVSQGKADMVMKGLVDTS
                     IILKAVLNKEVGLRTGNVLSHVAVFDVEGYDRLFFVTDAAMNLAPDTNTKKQIIENAC
                     TVAHSLDISEPKVAAICAKEKVNPKMKDTVEAKELEEMYERGEIKGCMVGGPFAIDNA
                     VSLEAAKHKGINHPVAGRADILLAPDIEGGNILYKALVFFSKSKNAGVIVGAKAPIIL
                     TSRADSEETKLNSIALGVLMAAKA"
     gene            4228..5307
                     /gene="buk"
                     /locus_tag="KRH23_001792"
     CDS             4228..5307
                     /gene="buk"
                     /locus_tag="KRH23_001792"
                     /EC_number="2.7.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0047761 - butyrate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006113 - fermentation [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="butyrate kinase"
                     /protein_id="HHS5225072.1"
                     /translation="MSKIFKILTINPGSTSTKIAVFDNEDLVFEKTLRHSSEEIGKYE
                     KVSDQFEFRKQVIEEALKEGGVKTSELDAVVGRGGLLKPIKGGTYSVSAAMIEDLKVG
                     VLGEHASNLGGIIAKQIGEEVNVPSYIVDPVVVDELEDVARISGMPEISRASVVHALN
                     QKAIARRYAREINKKYEDINLIVAHMGGGVSVGAHKNGKIVDVANALDGEGPFSPERS
                     GGLPVGALVKMCFSGKYTQDEIKKKIKGNGGLVAYLNTNDAREVEERIEAGDEKAKLV
                     YEAMAYQISKEIGASAAVLKGDVKAILLTGGIAYSKMFTEMIADRVKFIADVKVYPGE
                     DEMIALAQGGLRVLTGEEEAQVYDN"
     gene            5297..5974
                     /locus_tag="KRH23_001793"
     CDS             5297..5974
                     /locus_tag="KRH23_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HHS5225073.1"
                     /translation="MITNDKRIRIITGHYGSGKSEFAMNYVVKLRDMVSGKVAIADLD
                     VVNVYFRTREKKELMKSLGIQPIDSSINAPTLDLPAVSAEVMSPMVDHSYNSVIDLGG
                     DNVGARVIGRFSHLLKEGDYDMLFVINANREKTQTSEEVIQYIKEIEKSSKLKVTGLI
                     NNTHLIRFTTIDDVLRGQKVAKEVSEKCNIPIRYVACLENLVEQLPKDLEGEIFPIKL
                     YMREDWM"
     gene            6017..6232
                     /locus_tag="KRH23_001794"
     CDS             6017..6232
                     /locus_tag="KRH23_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HHS5225074.1"
                     /translation="MAKGKVSFNQERCKGCGLCVEACPVKIIQLDSNVINKKGYNPAT
                     VFEMEKCIGCASCATMCPDVVITVERD"
     gene            6261..7340
                     /locus_tag="KRH23_001795"
     CDS             6261..7340
                     /locus_tag="KRH23_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate dehydrogenase subunit
                     VorB"
                     /protein_id="HHS5225075.1"
                     /translation="MAKILMKGNEAFGKAAIEAGCKYFFGYPITPQSELPEYLSRELP
                     KIGGAFVQAESEVSAINMVYGGAGAGARVMTSSSSPGVALKQEGITYAVGAEVPCVVL
                     NVMRGGPGLGSIQPSQADYFMSTRGGGNGDYRTPVFAPATVQEAVDMIMEAFDVADYY
                     RSPVMVVADGMIGQMMEPVEFRAPEKKRELPPKDWATVGTKGKRKPNVINSLYLEPEV
                     LEDHCWHLQEKFDAMEKNEVQYEMYKTEDAEFVFAAYGTTSRVVKSAIDILREEGIKA
                     GLIRPKVLWPFPFEAFNQIPNARNILTVEMSMGQMVEDVKMAVEGKLPVYFHGRPGGM
                     TPTPAEIVEKAKKIIAGELVAGGAR"
     gene            7340..8092
                     /locus_tag="KRH23_001796"
     CDS             7340..8092
                     /locus_tag="KRH23_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent enzyme"
                     /protein_id="HHS5225076.1"
                     /translation="MAVVFKKTEGLQDTQTHYCPGCTHGIIHRLVGEVLEELGVLGDA
                     VGVVPVGCSVLGYKYFNCDTQEAAHGRAPAAATGIKRVHPENTVFTYQGDGDLASIGT
                     AEIVHAAARGEKITTIFVNNTTYGMTGGQMAPTTLVGQRATTAQSGRNAETQGYPIRV
                     SEMLATLTGAVFVERVAVDTPAHVRQAKKAIKKAFQVQQAGLGFGIVEVLSTCPTNWG
                     LAPNDALQWLRDNMIPYYPLGNFKNVEVEEVK"
     gene            8093..8650
                     /locus_tag="KRH23_001797"
     CDS             8093..8650
                     /locus_tag="KRH23_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016903 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoacid:acceptor oxidoreductase family
                     protein"
                     /protein_id="HHS5225077.1"
                     /translation="MSTARVICAGFGGQGVMSMGQLLTYAGMLEGKEVSWLPSYGPEM
                     RGGTANCAVTVSNEPVGSPLITDDATAAILLNIPAFEKFKDDVIPGGKIIVNSSLIKE
                     KVDRTDVDVYYIPANELAAELGNDKVANMIMLGAYLKVSDTVDIESVLEAFKKVFGPR
                     KEKFVPLNREALQKGMDATCSKATN"
     gene            8820..10166
                     /gene="glmM"
                     /locus_tag="KRH23_001798"
     CDS             8820..10166
                     /gene="glmM"
                     /locus_tag="KRH23_001798"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008966 - phosphoglucosamine mutase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HHS5225078.1"
                     /translation="MRKYFGTDGVRGVANTELTCDLAYKLGRAGGFVLAQGDHRVKVV
                     VGKDTRISGDMLEASLIAGLMSVGCDVITVGIIPTPAVAYLTRKYGADCGVVISASHN
                     PVEYNGIKFFNKNGYKLDDEIELKIEEYIDDIDKIDCLPIGENVGRKLHEHCAQRDYV
                     DYLKSIISTDFKGLKVVLDCANGASYKVAPIVFDELGASVISINSSPDGNNINYKCGS
                     THPEQLQRAVLEHNADLGLAYDGDADRLIAVNEKGQIVDGDHIMILSALNLKKNNKLA
                     QDTLVVTVMSNIGLTIAAKENGINLSTTAVGDRYVLEDMVKNGYNLGGEQSGHMIFLD
                     YNTTGDGVLSSLILANIILQEKKPLSEIASIMSQYPQVLVNATIKNENKNKYMEYPEI
                     KTEIERIESILDGNGRVLIRPSGTEPLVRVMLEGKEEGQIKELATNLANLIQEKLS"
     gene            10433..12265
                     /gene="glmS"
                     /locus_tag="KRH23_001799"
     CDS             10433..12265
                     /gene="glmS"
                     /locus_tag="KRH23_001799"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004360 - glutamine-fructose-6-phosphate
                     transaminase (isomerizing) activity [Evidence IEA];
                     GO_process: GO:1901137 - carbohydrate derivative
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HHS5225079.1"
                     /translation="MCGIVGYLGSRKAAEVIVEGLSKLEYRGYDSAGVAVNSSNEKEL
                     NIRKFKGRLSVLAEDLEKNPIDGNLGIGHTRWATHGEPSDVNSHPHFNQAKTIAVVHN
                     GIIENYMEIKEELISEGVKFESQTDTEVIAHLVDKYYEGNLLDAVYKTISKLRGAYAL
                     GVICKEHGNELVAVRKDSPLVVGVGEGENFIASDIPALLKYTRDVYFLENGEVVHLKD
                     ENVTVYDSNRNLVEKEVFHVTWDVEAASKGGYDYFMSKEIHEQPTGVRETLERRLDDN
                     GNIILDSINISKEDLEKINKVYIVACGTAYNAGLLGKYAIEKFVNIPVITDIASEFRY
                     SDPFVDENSLVILVSQSGETADTLAVLRDSKAKGARILSITNVVGSSIARESDDVFYT
                     WAGPEVAVASTKAYTTQITSLYMIALDFAIKKGTITREFYDSMISKMKEIPSKIQEIL
                     DNEEYIKEVAKTVVSSEHAFYLGRGIDYSLAMEGSLKLKEISYIHAEAFAAGELKHGT
                     IALIEKGTPVIAIATQEKLFEKMVSNMEEVRARGAYVVAIAQSHNKDVEKAADKIIYI
                     PNSDDILSPILAVVPMQLLAYHVSVLRGCDVDKPRNLAKSVTVE"
     gene            12717..14012
                     /locus_tag="KRH23_001800"
     CDS             12717..14012
                     /locus_tag="KRH23_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HHS5225080.1"
                     /translation="MTNDFKKEKKEDYFVNLKAISTEVLQEKVQDNAWVIVDTRLNDA
                     YNGWKLDGVKRGGHIKGAVDFSANWLSVYSDRKDEVLEQALKTKRIDLDKNIVLYDAN
                     GKDALVVADYLSKKGYKYLYKYDIKQWADDENLPMERYKNYQMIVPAFIIKDILDGKI
                     SETFEDSKNIKMIEASWGEESYTKGHIPTSVHVNTDIIEPPPTWMLDNDDNLTKFALD
                     YGLTKDDTVIVSSSTPMASYRLAVILRYIGVKDVRVLNGGTNSWLSAGYELEFISNPK
                     HSCTNFGADIPVNSQLIVTTSELRQKLKEKNKFILVDNRTWDEHIGKVSGYTYYDKKG
                     RIPGALYGHSGSDSVSLEEYRNIDNTMRNKYEILEMWDKENIDVNKQLIFMCGSGWRA
                     AEVLTYANVIGVENTSLYSDGWMGWSLDNSNLIEVGEHK"
     gene            14489..15226
                     /locus_tag="KRH23_001801"
     CDS             14489..15226
                     /locus_tag="KRH23_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YwmB family TATA-box binding protein"
                     /protein_id="HHS5225081.1"
                     /translation="MKKVKLAISFFILMIIGMTISYADTSINTRYNRLSKALEISEAN
                     FKFYNVKINSVINHNLSNKEFHNIFIEIINNLKLDKKGINWNQKGSGDKIQLCATIKG
                     SDKEISIKGINKNNKESYIVVDILDNKVYKHKEVIYSNVENVLNKYSSQVDVSACIVG
                     EYTKRLQNNKYDDILQKILYNMSAKQIDEVKDVNFLSITAYSKVLNDYELEYLGEKIN
                     LNIGIKYNEDDGKTLIYIATPIIKLDY"
     gene            15247..16500
                     /gene="murA"
                     /locus_tag="KRH23_001802"
     CDS             15247..16500
                     /gene="murA"
                     /locus_tag="KRH23_001802"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008760 - UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0019277 - UDP-N-acetylgalactosamine
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HHS5225082.1"
                     /translation="MAKIIVKKSNPLKGSVKIDGAKNAVLPIIAATLLANGKSTLNGV
                     PNLRDVHVISDLLRHVGAEVEYKENTLTVDASNIKTCEAPYELVRKMRASFLVMGPLL
                     ARFNSTKISMPGGCAIGTRPIDLHLKGFKALGAKIEMDHGFVEAATEKLVGNKLYLDF
                     PSVGATENIMMAASLAEGTTIIENAAEEPEIVDLANFLNEMGADVKGAGTNTIKIKGV
                     KELKGAEHNVIPDRIEAATYMVAAAMTKGDITVENVLMEHLKPVVAKLREAGCEITEM
                     DNSVRVVGPKVLKPIDIKTLPHPGFPTDVQAQFMAMLTVANGTGVVIETVFENRFMHV
                     AEFNRMGANIKIDGRSAVVNGVDELHGAAVNATDLRAGAALILCGLIAEGETQIGEIY
                     HIQRGYVDIDKKITALGGQIEIVED"
     gene            16587..17651
                     /gene="spoIID"
                     /locus_tag="KRH23_001803"
     CDS             16587..17651
                     /gene="spoIID"
                     /locus_tag="KRH23_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein D"
                     /protein_id="HHS5225083.1"
                     /translation="MKNPLVVLLGFVTCSVLVPSLITLVSYKNVELTEKPESPVSINK
                     TIKKSDIEDKGNKEEKNTVNYETVNKKAPIINVYNHITGKTEKMDMENYLCGVLAGEM
                     SSEFDIEALKAQSVAARTYVVYKQEHGKSSKHKNAVVCTDYKHCQEYKSYDTLKKLNG
                     EEWIKNKYSKIQEAVRGTKGQIITYNDKAILPLYFSTSSGKTENSEEVFSAKYPYLKS
                     VESPYDKYSPKFASTLKISNTDFVKSLRRAYSTIVIDVNNLSKQVSITKRSDAGTVEK
                     IKLGNKELTGKDIRTVFKLNSANFDIKFGEGYIDFVVKGYGHGVGMSQWGAEGMAEEG
                     YKYYDILSHYYTDTKIKDIY"
     gene            17717..18385
                     /locus_tag="KRH23_001804"
     CDS             17717..18385
                     /locus_tag="KRH23_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HHS5225084.1"
                     /translation="MKKKLLEKDGFYLSLFVCVCLLAVGGVWFTNNNVDKLASNKGIM
                     ENANKDSEEEIHLIEKDKKDAIPTATDSKQNLEKAKSKEENKSSTTKLNYIGDKVIRG
                     YSEKEPSYSKTLDVWETHKGVDISCTKGKEVKSLLNGIVVDVFDDEEYGQSVKIKSDN
                     NIVVVYSNLDKNVSVKKEQKVTEGQSLGTVGSTSQIESEEGIHVHLEAYSGEKSIDPM
                     SLIK"
     gene            18483..18743
                     /gene="spoIIID"
                     /locus_tag="KRH23_001805"
     CDS             18483..18743
                     /gene="spoIIID"
                     /locus_tag="KRH23_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140110 - transcription regulator activity
                     [Evidence IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation transcriptional regulator SpoIIID"
                     /protein_id="HHS5225085.1"
                     /translation="MRSHIEERAIVVAKYILEKNTTVRQTAKTFGVSKSTIHKDVTER
                     LKEINPSLAKEVKNVLDKNKSERHIRGGLATKLKYEKEHKKM"
     gene            18940..19959
                     /locus_tag="KRH23_001806"
     CDS             18940..19959
                     /locus_tag="KRH23_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein"
                     /protein_id="HHS5225086.1"
                     /translation="MAGADIGIDLGTANVLVYVSGKGIVLEEPSVVAIDKRTDSVLAV
                     GEEAKKMIGRTPGNIVAIRPLRDGVISDYDVTEKMLKSFIDKIVDKKGFGRFFMPRIM
                     VCVPTGVTEVEKRAVEDATRQAGAREVYIIEEPIAAAIGAGVDISQPNGNMIIDIGGG
                     TVDIAVISLGGAVVSESIKVGGDRFDDAIVKYMKKQHNLLIGERTAEKIKFEIGSAFK
                     REEEKYMKITGRNLITGLPSSITINSTEMLEALRECVEQIVVATHAVLEKTPPELAAD
                     IGDVGIIMTGGGSLLYGLDKIIEQRTGITVTIADEPLSCVAKGTGIALGSIDLLETGG
                     SFKRK"
     gene            19975..20403
                     /gene="fabZ"
                     /locus_tag="KRH23_001807"
     CDS             19975..20403
                     /gene="fabZ"
                     /locus_tag="KRH23_001807"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HHS5225087.1"
                     /translation="MLNIDEIKKLIPHRYPFLLVDKITELEVGKRAVGIKNVTVNEPF
                     FQGHFPEYPLMPGVLIVEALAQVCGVAMMSVEENKGKLGVFAGIDKVRIKREVRPGDT
                     LTMEVEMTTLRKNIAKADAKAYVGEELVCKGELMFALVEK"
     gene            complement(20514..21023)
                     /gene="yyaC"
                     /locus_tag="KRH23_001808"
     CDS             complement(20514..21023)
                     /gene="yyaC"
                     /locus_tag="KRH23_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore protease YyaC"
                     /protein_id="HHS5225088.1"
                     /translation="MYLAKVNYSDDDVIQMLSSVLKTIINENTIVVCIGTDRAIGDTL
                     GPLVGTILKNSNFKYPVYGTLDNPIHALNIYESLDTIKNTHIQGNFLAIDACLGSQSN
                     IGNIQIREGPILPGKGVGKKLPQIGNYSIVGIVDKIDENNKLSFNNIRLSFILDLAET
                     IALALLVST"
     regulatory      21212..21315
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            21452..22645
                     /gene="metK"
                     /locus_tag="KRH23_001809"
     CDS             21452..22645
                     /gene="metK"
                     /locus_tag="KRH23_001809"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004478 - methionine adenosyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006556 - S-adenosylmethionine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HHS5225089.1"
                     /translation="MARHLFTSESVTEGHPDKICDQISDSILDALLEKDPQSRVACET
                     TVTTGLVLVAGEISTSAYVDIPKLVRETVREIGYTRAKYGFDCDTCAVITSIDEQSGD
                     IAMGVDEGLESKTGEEIEEEIEKVGAGDQGIMFGFACNETPELMPLPISLAHKLSRRL
                     TEVRKTGLVDYLRPDGKTQVTVEYEGSKAVRVHTVLISAQHCETVSNDKIREDLINHV
                     IKEVIPAELLDEETKIYINPTGRFVIGGPQGDTGLTGRKIIIDTYGGYSRHGGGAFSG
                     KDPTKVDRSAAYAARYVAKNIVAAGLADKCEIELAYAIGIARPLSIFIDTFGTGKVSE
                     EKLVELVNKHFDLRPGAIIRDLDLRKPLYKKVAAYGHFGRTDIDLPWERTDKVEQLRK
                     DALGE"
     gene            22961..24058
                     /locus_tag="KRH23_001810"
     CDS             22961..24058
                     /locus_tag="KRH23_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YkvI family membrane protein"
                     /protein_id="HHS5225090.1"
                     /translation="MSGKVNIKTVISFAGAYVATVIGSGFATGQEILQFFTFYGYAGI
                     IGGIISMVLFSWFGAEVIDKGRELKLKEPIKIYQVYCGKYLGTFFEWFGPLFLFGTLV
                     IMIAGAGATLSEYYGLNPYVGRIGMAIVSLITVSLGLTRLSKILGNIGPIIIIFTLLV
                     GAISLFSNIDALSNAGNMVDSLNIKTATSNGYFSGVLYTCYNVIIVITFLTGMGASAV
                     NKKDAVWGGIVGGVALMAAAIMMNLALLSDIGNIYTKEIPALYLADKISPIIGILFSV
                     VLLLGIYTTAVPLLWSVTNRFVEDDHPKFKIITIVVSILACIGGLLPFDKLVGTLYPY
                     TGYMGILILLCMLYRRITKTEGYKENKSEIS"
     gene            24322..26541
                     /gene="recD2"
                     /locus_tag="KRH23_001811"
     CDS             24322..26541
                     /gene="recD2"
                     /locus_tag="KRH23_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0043139 - 5'-3' DNA helicase activity
                     [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SF1B family DNA helicase RecD2"
                     /protein_id="HHS5225091.1"
                     /translation="MEKLEGMISEIVFKNEDNGYTIAHLVNENDEIVVVGCMPTLAIG
                     ESIEVEGKWVNHKIYGTQFEVNSFMPVTPSSLEGIYVYLSSGMIHGIGEKMAKRIIDK
                     FGVDTLEVIQNSPEKLQEVEGIGSKKVKQIVKSYEEDRELRNIIIQLSPFGITPNYCL
                     KIYKKYKSSAIEVINKNPYQLAEDIRGIGFKVADSIASKIGIDKNSKDRICQGILYTL
                     NKSLSNGHTYLPEHVLIQDSEKLLELNGEILKECVMMLVYNQKIHIEKVNNENLIYLM
                     PYYLAENGVCSQIVKLSQYEFEDLKIDIDNEINVLEEDKKIKLAEKQILAVKESVNSG
                     VLIITGGPGTGKTTTINAIIDIFENNGKSVTLAAPTGRAAKRMSETSNKEAKTIHRLL
                     EMGFSTDDDLTFFKDEEDPINSDVIIVDEVSMVDIILMYNLLRAIKLGTRVILVGDSD
                     QLPSVGAGNVLKDMINSNIINVVKLNEIFRQAQESMIIVNAHKINNGEPLYLNTKGKD
                     FFFIRKSTNEEILNEIIGLVNERLPKFYKVDKLKDIQVLSSMRKGELGVTNLNIELQK
                     YLNKKEKFKVEESFSKRLFRVGDKVMQVKNNYTKKWETEDQKESGEGIYNGDIGYVYH
                     IDKDKKTIYILFDQTKIVSYLYDELDEIDHSFCTTIHKSQGSEFPVVVLPIAWAPPML
                     LSRNLLYTAVTRAKKLVVLVGDVKYLEYMIKNNRVNQRYSNLGYKLNKFKQEGLLIE"
     gene            26586..27326
                     /locus_tag="KRH23_001812"
     CDS             26586..27326
                     /locus_tag="KRH23_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HHS5225092.1"
                     /translation="MINKCLDFIYPENISCIICDKSIKKTNTYSICKSCFKEMNFIQD
                     GCMKCGKPIIRHSIEKEFIEECSYCFNKDFYFDKSISCIEYNDVTKKMVLGLKYNQKT
                     FMAKYIAQIMKEKLYLENIKFDYILFVPLHKKRLNKRGFNQAQKIAFNLSKIVNIPLL
                     DCISRKKYTRMLYKLNKKERKEELKNVFVVKENVKLINNKNILLIDDIFTTGLTTNEI
                     SKLLKLSGANKVFVLTLLTKANDNYIME"
     gene            27658..29571
                     /locus_tag="KRH23_001813"
     CDS             27658..29571
                     /locus_tag="KRH23_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HHS5225093.1"
                     /translation="MICLNKRQENLLTTLLLKEEFINVNKIANDFECSERTIRNDCKY
                     IDEWLSTFCNAYIKRKPNIGIKFSGDGTDKILVNQKLRGEVKRVNSELHKQVEILNLL
                     LCNNKKVTLNDLSNKLYINKNIVREEISKLSVALNNYNLNISTKKGSGIYIEGDEKDI
                     RIMLVSFLFKYIDKYRLNIDEIEYFHIVDIIIVKNIMLTIEEDMDIRLTDISFKQLML
                     FLLINIIRIRLGNSLKVSNTKKELKLKMLILDIEDELKSNLSIVLNYEEKLFIESLIL
                     GMNKQINSNNIKKSLYLNEELASYTKKIINLVSEESGINFNNDILLYEQLICHLNVTM
                     HQMKSNVYLENPLLDNIKTKFCFLFTVISSSIEIELKGKQITEDEIGYLTLHFQTSLE
                     RKYSKRESNKKASIVCPFSFGVSMLLKVKIEKRFDNIKIIETLREEDLKRDNFNKTID
                     FIIAFQEYENIQKPIFITTPLFTDEDENKLKEFTNKIKEKDTSYKLMNRLMMSDYLIR
                     ELEHDDIYEAITYLTNLLIEKHYAEKEYLQSIITREKSYPTNVGKGILFPHGDMKYIK
                     QSVLCFARLKTPIKIRNGKDIKIILLLAYKKDDDRKVFRELFKEISNLTEDENMLDIL
                     SKCDIEKVKDILI"
     gene            29712..30020
                     /locus_tag="KRH23_001814"
     CDS             29712..30020
                     /locus_tag="KRH23_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HHS5225094.1"
                     /translation="MEEIVLKIIIHAGNAKSMLYEALDYAKENDFKKADELIENANEE
                     ILKAHKVQTELIQKEAGGDKSDISILLIHSQDHLMTCMSERNLIKEMIMLRKEIQKLK
                     "
     gene            30044..30370
                     /locus_tag="KRH23_001815"
     CDS             30044..30370
                     /locus_tag="KRH23_001815"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HHS5225095.1"
                     /translation="MKRKVYLFCSFGMSTSLLADKMQKVADEHNLPIEVEAFPIAEID
                     KIVEEKNPDCILLGPQVKYMLKELKPKFEAQGKLIDIINEVDYGTMNGEKVLKLAIKL
                     IKSKQA"
     gene            30409..31743
                     /gene="celB"
                     /locus_tag="KRH23_001816"
     CDS             30409..31743
                     /gene="celB"
                     /locus_tag="KRH23_001816"
                     /EC_number="2.7.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0019191 - cellobiose transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HHS5225096.1"
                     /translation="MNRLERILMPLAEKIGKNKLLIAIRDGFLVSSPLLIIGSLFLLV
                     ANFPIKGWNEFVGQIFGPDWAVKLQQPTVATFEVMTLLAVLGIGYSYAKQIDVDPIAS
                     AAVAIVAFFIITPFVIPYTPEGTESVYMVTGIPLGWMGSKGMFVGMITAITSVKLFAA
                     VVKKGWTLKMPDGVPPTVSKSFAALIPSAIVMVVFFLVKIAFEATPYGSIHEFIFKFL
                     QMPLLKLGNSLGAMAIAYIFLHLFWFFGINGSSVVGAVYNPILKILSAENLAAFQAGS
                     KIPNIITGQFQDMFATFGGAGSTLSLVIAMLLICKSKRIKSMGKLSILPGIFGINEPL
                     IFGLPIMLNPILLIPFAIVPTINIIIAYFCMSAGLVPLTNGVQLPWTTPIIFSGFLTT
                     GWQGAVLQLVLLILGIFMYIPFIKMLDKQYLREENETVEEEDDDISFDDLVL"
     gene            31754..32272
                     /locus_tag="KRH23_001817"
     CDS             31754..32272
                     /locus_tag="KRH23_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GrdB-related putative oxidoreductase"
                     /protein_id="HHS5225097.1"
                     /translation="MKKIVMILDQIQAGAGGKEKSNIPPAGKSSPLGPGVMMEQFLNE
                     SKVIATLFCGDEFFVNNQEEVTSKMIAMVKKLNPDVVICGPSFNYENFSKMSAILSKN
                     INDKTDIPAFAAMSEENIDVINEYKNDICIVKTPKKGGIGLNDSLNNICKLAKAIANK
                     EDITLMKEEFCY"
     gene            32368..33327
                     /locus_tag="KRH23_001818"
     CDS             32368..33327
                     /locus_tag="KRH23_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase"
                     /protein_id="HHS5225098.1"
                     /translation="MWGMIATWRMALEGITEASEHLEKGMEAGDAVELAVRRVEDYPF
                     YKSVGYGGLPNENCEVELDAAFMDGNTLDIGAVAGIRDYSNPVSIARKLSYEKVNNFL
                     VGIGAEDYARKNGFERKNMLTDRAKLHYKKRKKETLDKGLSPYAGHDTVGMISLDKTG
                     KMCAATSTSGLFMKKRGRIGDSALSGSGFYVDSSIGGATATGLGEDLMKGCISYEIVR
                     LMKEGKHPQEACDIAVNELDKQLIKRRGKAGDLSLVAMNNKGEWGVATNIADFTFSVV
                     TKEESPTVYISNRVDGKTIHKVISNEWMEAYEARIKAPIEVSE"
     gene            33376..34428
                     /locus_tag="KRH23_001819"
     CDS             33376..34428
                     /locus_tag="KRH23_001819"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0016805 - dipeptidase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Sapep family Mn(2+)-dependent dipeptidase"
                     /protein_id="HHS5225099.1"
                     /translation="MNIISNKIDELKEDLLSDIIDIVKIPSVKGESENGFPFGEKVGE
                     ALNKALEISEKLGFKVRNLDNYIGYAEHGDSDDYVCVIGHVDVVHEGDGWKHQPYKGE
                     ETNGRIYGRGVLDNKGPIMSALYGLYAIKELNLKLDKRVRIIFGTNEESGFEDIPYYL
                     EKEKAPIMGFTPDCKYPVVYGEKGMAKIRIKSKINYEEDVYLGFIENMSENVLVTYKE
                     LNIENSDTILDIKVKYDFSYKLKDVLDEIKASFPNSIDIEVISNFNPVYFDKESNLVK
                     KLQLAYERVTSLDGTPVTTNGGTYAKVMPNIVPFGPSFPGQKGIAHNPDEYMGIEDII
                     LNAKIFANAIYELAKE"
     gene            34431..35105
                     /locus_tag="KRH23_001820"
     CDS             34431..35105
                     /locus_tag="KRH23_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005507 - copper ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HHS5225100.1"
                     /translation="MLEIIGMSVEDAKIIEDCGADRIELVSALTEGGLTPSFGLIESV
                     VNSVKIPVNVMIRHHAKSFVYSKEDISIMQKDISVVKEIGANGVVFGVLDKNNNIDEK
                     NLNVLLKCCDNLDVTFHRAIDESNTIDSVKILKDYDKITNILTSGGKGSIVDNIQMIK
                     NMMLSSNHIKILLGGGLNFNNIEKIKELTKASNFHFGTAIRINNSPFEDIDRQKLKQL
                     VNIISR"
     gene            35658..36209
                     /gene="hpf"
                     /locus_tag="KRH23_001821"
     CDS             35658..36209
                     /gene="hpf"
                     /locus_tag="KRH23_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0045182 - translation regulator activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome hibernation-promoting factor, HPF/YfiA
                     family"
                     /protein_id="HHS5225101.1"
                     /translation="MNIIISGKQIELTDAIKNKIETKLSKLDNYIHPDTDVKVTVSAR
                     KARQKIEVTIATVNGPIIRAEDMQENLYTAIDVVYDKLSKQLKKYKKRLQDKHKDNKS
                     IRFQDAEINLADEQEDYGDENQELVIQRRKKFSVKPMSEEEAVLQMELIGHDFYMFKN
                     IDSDEIAVVYKRNNGGYGIIEHE"
     gene            36341..39016
                     /gene="secA"
                     /locus_tag="KRH23_001822"
     CDS             36341..39016
                     /gene="secA"
                     /locus_tag="KRH23_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006605 - protein targeting [Evidence IEA];
                     GO_process: GO:0006886 - intracellular protein transport
                     [Evidence IEA];
                     GO_process: GO:0017038 - protein import [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HHS5225102.1"
                     /translation="MSFMDNLFNMADKKELKKFNKTVDIIDSLEPKFESMADSELKNM
                     TNIFKERLANGESIDDILPEAFAVVREVSKRVLGLRHYRVQMIGGIVLHQGRIAEMKT
                     GEGKTLVATAPVYLNALTGKGVHVVTVNDYLAKRDRDQMAKIYEFLGMSVGVIIHGQN
                     PKVRKEQYDCDITYGTNNEYGFDYLKDNMVIHKEQRVQRGLNYAIVDEVDSILIDEAR
                     TPLIISGPGDKSTHLYSDANTFVLTLKPDDYELEEKDKAVSLTASGIQKAEVYFNVDN
                     ITDISHTELYHHINQALRAHVIMKKDVDYVAKDGEIVIVDEFTGRLMFGRRYSEGLHQ
                     AIEAKEGLKIQRESKTLATVTFQNYFRMYKKLSGMTGTAKTEEEEFKAIYKMDVFQVP
                     TNKLMIREDLPDCVYKSEIGKFNAVAQEIIERHKVNQPILVGTVSIEKSELLSQILKK
                     KGIKHEVLNAKHHDKEAEIIAQAGRLGAVTIATNMAGRGTDIVLGGNPDFLTKREMRR
                     NGFKEEIVNRVDTPIEGIPVKGNEILFEAREEYEKLFEKFKQQTQEEQKQVVEAGGLA
                     IIGTERHESRRIDNQLRGRAGRQGDPGSSRFYIGLDDDLMRLFGSDRISGIVDKIGLE
                     EDMPIEHRILSKSIEGAQKKVEGKNFGIRKHVLQYDDVMNKQREIIYAERKRVLEGED
                     LQEQIQSMTHSIIEEAVTLYTQDKGFDEEGFKEHMYNLFLPKGSIEIPEIEKLNPVEI
                     TEKVYEIAMKIYTSKEEQVGYERMREVERVILLQAVDNHWIDHIDAMDQLRQGIGLRA
                     VGQQDPVIAYKMEGFDMFDEMNKHIKEDTVRYLFNITIETPVERKAVVDVENLSSPSD
                     GTLPTSKTVKKDEKVGRNDLCPCGSGKKYKNCCGR"
     gene            39031..40138
                     /gene="prfB"
                     /locus_tag="KRH23_001823"
     CDS             join(39031..39105,39107..40138)
                     /gene="prfB"
                     /locus_tag="KRH23_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_153309863.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0016149 - translation release factor
                     activity, codon specific [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HHS5225103.1"
                     /translation="MLKLQEYRHSMEQMASNLEELRVSLDIASLMKNIQINEEKMNQQ
                     DFWNDNEVAQRVLQENKSLKETLEEYESLKSLLEDIEVLIEIGLEEDDDSVERDIEKS
                     IESMEEKLSEMKIKTLLNGEYDKNNAILSINAGTGGLDAQDWAQMLLRMYIRWSESKG
                     YKVKLLDIISDPEAGIKTATILVEGTNAYGYLKSEKGVHRLVRISPFDPSGKRHTSFA
                     SIDVTPELDENIEVEINPSDLKIDTYRASGAGGQHVNTTDSAVRITHIPTGVVVQCQN
                     ERSQHLNKDRAMRLLMAKLIELKELEQKEKIEDIQGKYSQITWGSQIRSYVFQPYKLV
                     KDHRTNAEFGNVDSVMNGNIDLFINEYLKMNKIV"
     gene            40282..42423
                     /locus_tag="KRH23_001824"
     CDS             40282..42423
                     /locus_tag="KRH23_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003729 - mRNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Tex family protein"
                     /protein_id="HHS5225104.1"
                     /translation="MDINQILKKEFNLRDEQINNTLKLIDEGNTIPFIARYRKEMTGE
                     MSDVTLREFYEKLMYLRNLQSRKDDVVRLIDEQGKLTDEITQNIEKAKTLQEVEDIYA
                     PFKQKKRTRATIAKEKGLENLALSILENNLDNIEIEAKNYLDEEKEVLSIEDALKGAR
                     DIIAELVSDDAKIRKYIRELALREGMIVSKSATDEKSVYDMYYDYSEAVKSMAPHRVL
                     AINRGEKESFLKVKLEINNDKVLNYIINEYVNDKNFKNKEEIVSSIEDSYKRLIFPSI
                     EREIRNHLTEIAQERAISVFGKNVKSLLLQPPVKDKVVMGFDPAFRTGCKIAVVDKNG
                     KLLDYTTVYPTDPQNDVEGAKKVLKGLIEKYDIDIISIGNGTASRESETFVSEMIKEI
                     DSEVQYVIVSEAGASVYSASELANEEHPDINVSIRGAISIARRLQDPLAELVKIDPKS
                     IGVGQYQHDLNKKRLEEVLDGVVEDSVNSVGVDLNTASYSLLEHVAGISKAIAKNIIA
                     YREENGDFTSRAQLKKVKRLGPQAFTQCAGFMRILEGKNPLDNTGVHPESYDICKKMI
                     EIIGYSLDDVKNKNIGEIDEKIKEIGLRELSEKLEVGQVTLKDIIAEIKKPGRDPREE
                     GIKPILRTDVLKIEDIQEGMTLKGTIRNVVDFGAFVDIGIKNDGLVHKSEMSNSFVKD
                     PMSIVTVGDIVDVKVIGIDLNKKRVALSMKK"
     gene            42571..43737
                     /locus_tag="KRH23_001825"
     CDS             42571..43737
                     /locus_tag="KRH23_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HHS5225105.1"
                     /translation="MIFIKNGKINTITNGIIHGDILIDEGKIIEIGEDLIAPLDVEVI
                     DASNKLVFPGFIDAHTHLGLWEDGIGFEGADGNEETDPITPQLNPIDGINPMDRTFKE
                     AFEGGITSVCTTPGSANVMGGQCIAIKTCGKRIDKMVIKNPVASKIAFGENPKSCYGQ
                     DDKSPQTRMAIAALLRENLKKAEEYLEDIDMYESHDDEDCEKPEYDIKMESLIPVLRR
                     EIPFKAHAHRADDMFTAIRIAKEFNLKLTLDHCTEGHLIVDELVEEGFPVIVGPSLSE
                     RSKFELRNLTFNTAGILSNAGLDVCIMTDHPVIPVQYLPICAGIAVKHGMKEEKAIES
                     ITINPAKTLGIEDRVGSIEVGKDADLVIWDNSPLEIQSNVLYTIINGKVVYEKK"
     regulatory      43797..43914
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            44039..44644
                     /locus_tag="KRH23_001826"
     CDS             44039..44644
                     /locus_tag="KRH23_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HHS5225106.1"
                     /translation="MQNTAKRGNMISTRTLVVMSILSAISYLLMFIQAPIPGIFPDFL
                     KIDLSDIPAIFGGMSLGPLVGFGIVVVKNVLQAITATTTGGIGEFANILIGGSYVMIL
                     CYSYKRSGDLKGVLIGFVLGTISMTIIGSLVNYFVMLPLYGQLMGLDAIIGLGSAINP
                     QVHDLFTFVIWMIAPFNVLKAVIISLVTLPLYKKMGNIIKK"
     gene            44973..46013
                     /locus_tag="KRH23_001827"
     CDS             44973..46013
                     /locus_tag="KRH23_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4116 domain-containing protein"
                     /protein_id="HHS5225107.1"
                     /translation="MHLSKKIKKLFLDDKGYYFNSNWKDIHIGIYDTKLGDSLKYITN
                     EYIENMERVKYDYRELKNIENQTDGMCILAIRQNYKALEYVKNQTEELCLEAIKYNYK
                     ALEYVKEQTEYLCLEAIKKDCNALKYVRNKTEGLIIKAISHSSNIDVVSILKALETQT
                     RRICLEAIKKDGRCLAYVREQSEELCIEAIKQNYKALKYVKNQTEKMCIESVRQNGMA
                     LQYVNKQTDKICIEAVKQDGRSLQFVNNKTEEICINAIRYLNKKYNIKDVLSYIDKYT
                     ENICIEIVRQNGKMLMYIKNQTEKMCIEAVKENYKSLKYVKEQSERICKEALKQNHKA
                     KEYVKIAIDDCI"
     gene            46152..46604
                     /gene="tsaE"
                     /locus_tag="KRH23_001828"
     CDS             46152..46604
                     /gene="tsaE"
                     /locus_tag="KRH23_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HHS5225108.1"
                     /translation="MAKIYLENENKTREIGYKLGKLLKEGSVICLVGDLGAGKTTMTQ
                     SLADSLGIEDYITSPTFTIINEYEGKIPLYHFDVYRIGSSDEMYDIGYDEYVNSNGIC
                     IIEWANLIEDILPKEYLNIELRYKDEGREMILTPKGEFYKEIVEELIK"
     gene            46604..47320
                     /gene="tsaB"
                     /locus_tag="KRH23_001829"
     CDS             46604..47320
                     /gene="tsaB"
                     /locus_tag="KRH23_001829"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HHS5225109.1"
                     /translation="MKILGMDTSSMAASVAVVEDDNLICEFTVNNKKTHSQKLMPMIE
                     NMLSMSDLSIKDMDLLAVCIGPGSFTGLRIGMATVKAMAHVNNIPIIAVNSLESLANN
                     INFCDRKICCILDAQKNQVYSAKYKFENGEMIELDGVDVVEFDALVDEIVSTNEEFII
                     VGEAVYKYKDKLENIKNIKIPSPANNVSNAGSLCSLALNKYNKNIDVHTCYTINPMYI
                     RKSQAEVQYDEKMKRLNNGR"
     gene            47310..47786
                     /gene="rimI"
                     /locus_tag="KRH23_001830"
     CDS             47310..47786
                     /gene="rimI"
                     /locus_tag="KRH23_001830"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008999 - protein-N-terminal-alanine
                     acetyltransferase activity [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HHS5225110.1"
                     /translation="MEDNTKLIVDDIKIEEMTTEDIDEVFEVEKNCFEDYWSKESFRK
                     ELSNEVARYIVAKLNGKIVGYVGIWLILDEGHINNVAVHSDYRGKKIGDKLIKGIVDL
                     CKDNNIASMTLEVRASNKIAQNLYRKYGFKMGGIRKEYYSDNKEDAIIMWNQLKEV"
     gene            47792..48808
                     /gene="tsaD"
                     /locus_tag="KRH23_001831"
     CDS             47792..48808
                     /gene="tsaD"
                     /locus_tag="KRH23_001831"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HHS5225111.1"
                     /translation="MSDIITLAIESSCDETAASVLKNGREVLSNIISTQIETHKKFGG
                     VVPEVASRKHVENIDIVVQEALDKANIGFNDIDHIAVTYGPGLVGALLVGLSYAKALA
                     YTLNIPLVGVNHIEGHLSANYIEHKDLKPPFITLIVSGGHTHLVEVKDYGKYEILGKT
                     RDDASGEAFDKISRAMNLGYPGGPIIDNLAKNGNKHAIEFPRAYLEEDSYDFSFSGLK
                     SSVLNYLNGKRMKNEEIVVEDVAASFQEAVVEVLSTKALKAVKDKGYNIITLSGGVAS
                     NSGLRAKITELAKDNGITVKYPPLILCTDNAAMIGCAGYYNFINGKTHDMSLNAVPNL
                     KINQ"
     gene            49105..51813
                     /gene="hpdB"
                     /locus_tag="KRH23_001832"
     CDS             49105..51813
                     /gene="hpdB"
                     /locus_tag="KRH23_001832"
                     /EC_number="4.1.1.83"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxyphenylacetate decarboxylase large
                     subunit"
                     /protein_id="HHS5225112.1"
                     /translation="MSQSKEDKIRSILEAKNIKSNFQNKENLSEFNEKKASKRAEDLL
                     DVYYNTLSTADMEFPYWYNREYRKSDGDIPVVRRAKALKAAFSHMTPNIIPGEKIVMQ
                     KTRHYRGSFPMPWVSESFFVAQGEQMREEAKKLASNTADELTKFGSGGGNVTESFGNV
                     VSIAGKFGMRKEEVPVLVKMAKEWVGKSVEDLGFHYEKMMPDYDLKENLMSTLICMFD
                     SGYTLPQGREVINYFYPLNYGLDGIIEMAKECKKAVAGNASGDGLIGMDRLYFYEAVI
                     QVIEGLQTWILNYAKHAKYLESIETDLEAKKEYSDLVEILEHIAHKQPRTFREALQLT
                     YTIHIASVNEDAISGMSIGRFGQILYPWYEQDIEKGLITKEEVIELLELYRIKITCID
                     CFASAGVNGGVLSGNTFNTLSIGGLKEDGSTGANELEELLLEASMRCRTPQPSLTMLY
                     DEKLPEDFLMKAAECTKLGSGYPAWVNNSNGTTFMMKQFADEGMTVEEARAFALGGCL
                     ETSPGCWKQLTLNGKTYSIAGGAGQSAGSGVHFIANPKILELVLMNGKDYRMNIQVFE
                     PHNKPLDTYEEVIEVFKDYYKQAINVLERANNIELDIWRKFDTSIINSLLKPDCLDKG
                     QHIGNMGYRYNATLNVETCGTVTMVNSFAALKKLVYDDKAFTIEEMKDAILNNFGFKD
                     ALEVGNYSMADQVKVDKTGKYDAIYKACLDAPKYGNNDLYADNILKNYEVWLSKVCEE
                     AQSLYAKKMYPCQISVSTHGPQGAATLATPDGRLSGTTYSDGSVSAYAGTDKNGVYAL
                     FESATIWDQAVVQNSQMNLKLHPTTIKGQQGTKKLLDLTRSYLRKGGFHIQYNVVDSE
                     TLKDAQKNPDNYRQLMVRVAGFTQYWCELGKPIQDEVIARTEYEGV"
     gene            51817..52074
                     /gene="hpdC"
                     /locus_tag="KRH23_001833"
     CDS             51817..52074
                     /gene="hpdC"
                     /locus_tag="KRH23_001833"
                     /EC_number="4.1.1.83"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxyphenylacetate decarboxylase small
                     subunit"
                     /protein_id="HHS5225113.1"
                     /translation="MRKHSDCMNFCAVDATKGICRLSKQMINLDDAACPEIKVMPKCK
                     NCKNFVEANDEGIGKCVGLEKEDWVYSTLNAITCEGHVFNE"
     gene            52067..53017
                     /gene="hpdA"
                     /locus_tag="KRH23_001834"
     CDS             52067..53017
                     /gene="hpdA"
                     /locus_tag="KRH23_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxyphenylacetate decarboxylase activase"
                     /protein_id="HHS5225114.1"
                     /translation="MSSQKQLEGMIFDVQSFSVHDGPGCRTTVFLNGCPLSCKWCANP
                     ESWTVRPHMMFSELSCQYENGCTVCHGKCKNGALSFNLDNKPVIDWNICKDCESFECV
                     NSCYYNAFKLCAKPYTVDELVQVIKRDSNNWRSNGGVTFSGGEPLLQHEFLHEVLLKC
                     HEVNIHTAIETSACVSNEVFNKIFNDIDFAFIDIKHMDREKHKEQTGVYNDLILENIS
                     NLANSDWNGRLVLRVPVISGFNDSDENISDIISFMHKNNLVEINLLPFHRLGESKWTQ
                     LGKEYEYSDKGDVDEGHLEELQDIFLDNGIACYVGHETAF"
     gene            53332..54294
                     /locus_tag="KRH23_001835"
     CDS             53332..54294
                     /locus_tag="KRH23_001835"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0071586 - CAAX-box protein processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane glutamic
                     endopeptidase"
                     /protein_id="HHS5225115.1"
                     /translation="MNKSWSNLIIKNKDRKVRSGWIIIAVMATFYILQYYLSMILVEI
                     IRKILVATGDINLKTNYFSEYANWLNDVGLQIVFQILTDSLMIIIPIIVWRFIMKNPI
                     SEMGLHSYRIKKKEGYVGMLLGIFNCTVIFIITITIGGGHVTSWVPKISPLTVSWILV
                     FILVAFAEEILNRGFFMAVLRRCKNIYFIMIVPSVIFGLIHIWNPDVTFLSVINIIII
                     GILFSYMFIKSSNIWMCIGYHFTWNVFQGIIYGMPVSGLQVPGIITTQITHGNLLNGG
                     MFGIEGGILTTFVNLLSFIFVWYYYRDSKYDFVSDKVNVTNIKN"
     gene            complement(54393..55373)
                     /locus_tag="KRH23_001836"
     CDS             complement(54393..55373)
                     /locus_tag="KRH23_001836"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0071586 - CAAX-box protein processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane glutamic
                     endopeptidase"
                     /protein_id="HHS5225116.1"
                     /translation="MNLKLIWINILNPVFIKNEIKRKKIQIIIFFFINFGLTYSLGLL
                     LYYNKFIDPENFASFMMILPLSSVAIAKFYTEGLNNDMYEFYSLIILFFLIYSLLIVL
                     KLLNLINNNEFIIINLILTFISSLSIIIYSSNKKNLYPVKNIKLGSLLIIYFMISVIV
                     PTSFILILQGAQPNYSGIIKFIFTPITSLTTIYIFFSEEYAWRGFLQNIFFDKFGKKL
                     GVIILGMCWSLWHLPLIFTLYTPEAPILGIILRSIHIVGISIFLGYLYIKTKNIWFCA
                     IIHVLNNSAFLITNSKESTITYHDILIVSMVVLIFYVPFLFTKEYKNNLE"
BASE COUNT        22514 a         5875 c        10469 g        16986 t
ORIGIN      
        1 taagaaaagt ttactataaa ttatagtaaa cttttatatt gtttaaaaag acacaggaaa
       61 catgtatatt acctgtgtct ttttatttat aaattttaaa ctatgtaaaa attacagtat
      121 attctaatag agttacagta tattcattaa tattgtaaac atacggaggg taatgtataa
      181 tagtctacaa gatgtttatg aaggcatcag ttaaatataa taaatataac taattagtaa
      241 gagttatata cattatattg tatactttat ggtatttata tattgaaata acttatgaaa
      301 ttatttataa agagattcat gagcatattt ttgtctaaac aataagtata agaaattata
      361 aaaaattaga gactatagtg aatttacaat ttaatgtaat atttataagt tatactaaat
      421 aaattattat actgtgaaat ggatatataa ctttaggtat tgtgtattat tttcactgta
      481 ggagattata tctagttata cataataagt tttaatgata gtttatagta agatattaaa
      541 ataaatttat ctaatctaga tatgaaataa gttattactt taatataaaa atgaatctaa
      601 tggaataata ttgatgataa gtaatattta gattttgtat ttgtttatag ttaataagtg
      661 gattatagaa tttataataa ttaatatata ttaaacaaag atatattaag atattttaga
      721 gcataaaact gaattaaggc gcgagtacta ttttgtattc gcgccttgat ggtttgagtt
      781 atttgagtaa aaactaactt taataagaaa tatgtattta ttaagttgat atttttaatg
      841 tgtttagaga ttatttaaca atctccaaat ataaaactag aattatttac ataaaagtta
      901 aatagtttgt atagagttag atttatatag tataatactt agtgtaaata attaagaagt
      961 tatcaaacag gaggataaaa ctgtgttaga tataaattct tttttaaatg gattttttaa
     1021 tataatatta agaatgagta tatatgattt aattgacata tctatagtag cgtatatttt
     1081 ttacaaaata tttatgttta taaaagatac aagagcagaa caagtgttta aaggtataat
     1141 atttctttta ttagcaactc aacttagtaa cacctttaaa ttgcataccg tttattggat
     1201 atctcttaaa gctttagatt atggagttat agctgctctt ataatttttc aaccagaatt
     1261 tagagcagga cttgaacata taggaagagc aaagtttaat ttatttggaa agaatgtaaa
     1321 tacttctgaa gaaactctca atagaaatat agaagaaatt gtagaagctt tatattcact
     1381 ttctagacaa aaaataggag ctcttatcat aatggagaga gaaactagaa taagtgatat
     1441 aataaataca ggaactatta ttgatgctga aatttctagg caactattaa taaatatatt
     1501 tataccaaat acaccattac acgatggagc tgttgtaatt agagattcta aggtaaaagc
     1561 agctgcatgt tttttgccat tgacagaaag taaggattta agtaaagatt tgggcactag
     1621 acatagagca ggaatagggg taagtgaggt gtctgactgt ataactttga ttgtatcaga
     1681 ggaaacaggt ggcgtatcaa ttgctaaagc aggtaagtta tatagagata tttctagaga
     1741 aagaatgatg aatatattac gtagtaattt aaaaacaaat acagaaacaa gaagtttttt
     1801 caaaggtggt atatttaaat gataaataga ctaaaaaata ataccaaaat aaaaataata
     1861 tcatttttaa gtgcaattgc attatggatg tatgttatgg ctgtagttga ccctgaagaa
     1921 actaaagggt ttgaagatat acctgtatct ataagtaata tgagtgattt aaaggataaa
     1981 aatcttgtta tatatccaga cgaaaaatta acagcagatg tatatataaa aggtagttta
     2041 tcaaaggtac aaagtgttaa aaaagaagat atacatgtat atggaaccat tgaagaccca
     2101 atacaaggac agaaggaagt atatttaaaa gcaaatattc ctcaaggtgt tactctagaa
     2161 tttaagcatg atgttttagt agtaaatctt gaaaaaaaca taaaagaaaa aagagatata
     2221 aaggtagaag taagtggaaa ttcaaaaaga aatataaata aaattgaact tagtaaggaa
     2281 tttgtcgatg tatcaggtcc aagaactcta gttaaagaag tcaaaagtgt aagagctaat
     2341 ctagatgttg gtaatgagac agatgatttt tctaaaaaat tgcaattaat accattaaat
     2401 agtgatggaa ctaaggttga aggagtaaca ttaagttcat cctttgtgac tgcaaagata
     2461 gagctattga aggaaaaaat tgtcccaata agagtaagtc taaatgataa taaagataat
     2521 gatgtactga aaaactataa attaagtaag gaacaagtta caataaaagg aaagaaagat
     2581 gatatagaca aaataagtta tattaagaca aaacctattg acttagctga tttggctaat
     2641 ggtgaagaaa aagaagttag cttagaaatt ccagagggta taactcttga ggatagctct
     2701 ataacaatta aattaaatga tacaaaacaa ttgagtgcag aatttttata taatgcggga
     2761 gatattgaat taagaaatat cccaacaaat atggataatc caaatgtaat ttctgatgta
     2821 gatataaaag ttgttgtaga gtcaacggag gatttgagta agttaaataa aaaagatatt
     2881 tcattatata ttgatttatc acaaggtcct gaggaagata gtaaatataa aataaaatat
     2941 gaaacaacat atcaatttaa aaaaataaat atagaaccta atattgttga agtggaatga
     3001 acaaatattt cgaatattta gttgttacaa gatgcgacaa aaaaacctat aaaattaagt
     3061 ttgttaattt tatgtttttg ttgcatcttg tttattttag ttatattata aaataaggac
     3121 aatgagatat ttgttaaatc taaaaagcgc tagatatatg aaaaaagact gataaataga
     3181 tttaaataaa tattttgaat taaatatttc aattatctct aggaaaacgt tgctgaacga
     3241 gttataattt aattgagata taaaaagttc tatttcaaaa aattcaagat gaggtggaaa
     3301 tgcatgagaa gttttgaaga agtaattaag tttgcaaaag aaagaggacc taaaactata
     3361 tcagtagcat gttgccaaga taaagaagtt ttaatggcag ttgaaatggc tagaaaagaa
     3421 aaaatagcaa atgccatttt agtaggagat atagaaaaga ctaaagaaat tgcaaaaagc
     3481 atagacatgg atatcgaaaa ttatgaactg atagatataa aagatttagc agaagcatct
     3541 ctaaaatctg ttgaattagt ttcacaagga aaagccgaca tggtaatgaa aggcttagta
     3601 gacacatcaa taatactaaa agcagtttta aataaagaag taggtcttag aactggaaat
     3661 gtattaagtc acgtagcagt atttgatgta gagggatatg atagattatt tttcgtaact
     3721 gacgcagcta tgaacttagc tcctgataca aatactaaaa agcaaatcat agaaaatgct
     3781 tgcacagtag cacattcatt agatataagt gaaccaaaag ttgctgcaat atgcgcaaaa
     3841 gaaaaagtaa atccaaaaat gaaagataca gttgaagcta aagaactaga agaaatgtat
     3901 gaaagaggag aaatcaaagg ttgtatggtt ggtggacctt ttgcaattga taatgcagta
     3961 tctttagaag cagctaaaca taaaggtata aatcatcctg tagcaggaag agctgatata
     4021 ttattagccc cagatattga aggtggtaac atattatata aagctttggt attcttctca
     4081 aaatcaaaaa atgcaggagt tatagttggg gctaaagcac caataatatt aacttctaga
     4141 gcagacagtg aagaaactaa actaaactca atagctttag gtgttttaat ggcagcaaag
     4201 gcataatttt aagggggaaa taggcaaatg agcaaaatat ttaaaatctt aacaataaat
     4261 cctggttcga catcaactaa aatagctgta tttgataatg aggatttagt atttgaaaaa
     4321 actttaagac attcttcaga agaaatagga aaatatgaga aggtgtctga ccaatttgaa
     4381 tttcgtaaac aagtaataga agaagctcta aaagaaggtg gagtaaaaac atctgaatta
     4441 gatgctgtag taggtagagg aggacttctt aaacctataa aaggtggtac ttattcagta
     4501 agtgctgcta tgattgaaga tttaaaagtg ggagttttag gagaacacgc ttcaaaccta
     4561 ggtggaataa tagcaaaaca aataggtgaa gaagtaaatg ttccttcata catagtagac
     4621 cctgttgttg tagatgaatt agaagatgtt gctagaattt ctggtatgcc tgaaataagt
     4681 agagcaagtg tagtacatgc tttaaatcaa aaggcaatag caagaagata tgctagagaa
     4741 ataaacaaga aatatgaaga tataaatctt atagttgcac acatgggtgg aggagtttct
     4801 gttggagctc ataaaaatgg taaaatagta gatgttgcaa acgcattaga tggagaagga
     4861 cctttctctc cagaaagaag tggtggacta ccagtaggtg cattagtaaa aatgtgcttt
     4921 agtggaaaat atactcaaga tgaaattaaa aagaaaataa aaggtaatgg cggattagtt
     4981 gcatacttaa acactaatga tgctagagaa gttgaagaaa gaattgaagc tggtgatgaa
     5041 aaagctaaat tagtatatga agctatggca tatcaaatct ctaaagaaat aggagctagt
     5101 gctgcagttc ttaagggaga tgtaaaagca atattattaa ctggtggaat cgcatattca
     5161 aaaatgttta cagaaatgat tgcagataga gttaaattta tagcagatgt aaaagtttat
     5221 ccaggtgaag atgaaatgat tgcattagct caaggtggac ttagagtttt aactggtgaa
     5281 gaagaggctc aagtttatga taactaatga taaaagaata agaatcataa ctggtcacta
     5341 tggaagtggt aaaagtgaat ttgcgatgaa ctatgttgtt aagttaagag atatggtttc
     5401 tggcaaagtt gctatagccg atttagatgt ggtaaatgta tactttagaa ctagagaaaa
     5461 gaaagagtta atgaaatcct taggtataca accaatagat agctcaatta atgctccaac
     5521 attagattta ccagcagtat cagcagaggt aatgtctcct atggtagacc attcatacaa
     5581 ttctgttata gatttaggtg gagataatgt aggtgctagg gttataggaa gatttagtca
     5641 tttgttaaaa gaaggcgatt atgatatgct ttttgtaata aatgcaaata gggagaaaac
     5701 tcaaacttct gaagaagtta tccaatatat aaaagaaata gaaaaatctt ctaaattaaa
     5761 ggtaacaggt ctaattaata atactcatct tattaggttt actactattg atgatgtttt
     5821 aagaggtcag aaagttgcaa aagaagtttc tgaaaaatgt aatataccga taagatatgt
     5881 tgcatgttta gaaaatcttg ttgaacagtt accaaaagat ttagaaggag aaatttttcc
     5941 tataaaatta tatatgagag aagactggat gtagtttgag ctcaaatata tagaaagttt
     6001 aaggaggctt aggtaaatgg ctaaaggaaa agtatctttt aatcaagaac gttgtaaagg
     6061 ttgtggattg tgtgttgaag catgtccagt aaaaatcata caattagact caaatgtaat
     6121 aaacaaaaaa gggtataacc cagcaactgt ttttgaaatg gaaaaatgca taggatgtgc
     6181 aagttgtgca actatgtgtc cagatgtagt tataacagta gaaagagatt aatttaatta
     6241 atatttaagg gggaatttta atggctaaga tacttatgaa aggtaacgaa gcatttggaa
     6301 aagcagctat agaagctggt tgcaaatatt tcttcggtta cccaataact ccacaaagtg
     6361 aattaccaga atatttatca agagagttac ctaaaatagg tggagcgttc gttcaagctg
     6421 aatcagaagt ttctgcgata aacatggttt atggtggagc aggtgcagga gcaagagtta
     6481 tgacttcttc atcttcacca ggagttgctt taaagcaaga aggtataaca tatgcagtag
     6541 gagcagaagt tccttgtgtt gtacttaatg taatgagagg tggtccagga cttggaagta
     6601 tacaaccttc acaagctgac tactttatgt ctacaagagg tggaggaaat ggagactaca
     6661 gaactccagt attcgcacca gctacagttc aagaagctgt tgatatgata atggaagctt
     6721 ttgacgttgc agattattac agatcaccag ttatggtagt tgcagatggt atgataggtc
     6781 aaatgatgga gccagttgaa tttagagctc ctgagaagaa aagagaattg cctcctaaag
     6841 attgggcaac tgttggaact aaaggaaaaa gaaaacctaa tgtaataaac tctctatact
     6901 tagagccaga agtactagaa gaccattgtt ggcatttaca agaaaaattt gatgcaatgg
     6961 aaaagaatga agtacaatac gaaatgtaca aaacagaaga tgctgaattt gtatttgcag
     7021 cttatggaac tacttcaaga gtagtaaaaa gcgcaattga tatattaaga gaagaaggaa
     7081 taaaagcagg tcttataaga cctaaagtat tatggccatt cccattcgaa gcattcaacc
     7141 aaattcctaa tgctagaaac atattgactg ttgaaatgag tatgggacaa atggtggaag
     7201 atgttaaaat ggcagtagaa ggtaaattac cagtttactt ccatggaaga ccaggaggaa
     7261 tgactccaac accagcagaa atagttgaaa aagctaaaaa aattattgcc ggagaattgg
     7321 ttgcaggagg tgctagataa tggctgttgt atttaagaaa actgaaggat tacaagatac
     7381 tcaaactcac tactgtccag gatgtacaca tggtataatc catagattag ttggtgaagt
     7441 attagaagaa ctaggagtat taggtgatgc tgtaggtgtt gttccagttg gatgttcagt
     7501 tttaggatat aaatatttta actgtgacac tcaagaagct gctcatggta gagcgccagc
     7561 tgctgctaca ggaataaaaa gagttcatcc tgaaaataca gtattcactt atcaaggtga
     7621 tggagactta gcttcaattg gtactgctga aatagttcat gcagctgcta gaggagaaaa
     7681 aataactact atatttgtaa acaatacaac ttatggtatg actggtggac aaatggctcc
     7741 aactacatta gttggacaaa gagctactac tgctcaatca ggaagaaatg ctgaaactca
     7801 aggttatcca ataagagtaa gtgaaatgtt agctacatta acaggagctg tatttgtaga
     7861 aagagtagca gttgatactc cagctcatgt tagacaagct aaaaaagcta taaagaaagc
     7921 attccaagtt caacaagcag gattaggatt tggaatagta gaagtattat ctacttgtcc
     7981 tacaaactgg ggactagctc caaatgatgc tttacaatgg ttaagagaca acatgatacc
     8041 atactatcca ttaggaaatt tcaaaaatgt tgaagttgag gaggtgaagt aaatgtctac
     8101 agctagagta atatgtgcag gcttcggagg ccaaggtgtt atgtctatgg gacaattact
     8161 tacttatgca ggaatgctag aaggaaaaga agtttcttgg ttaccatctt atggaccaga
     8221 aatgcgtgga ggtacagcaa actgtgcagt aactgtatct aatgagccag ttggttctcc
     8281 acttataaca gatgatgcaa ctgcagctat attattaaat ataccagcat ttgaaaaatt
     8341 caaagatgat gttattcctg gtggaaaaat aatagtaaat agttctttaa taaaagaaaa
     8401 agttgataga acagatgtag atgtttatta tataccagca aatgaattag cagctgaatt
     8461 aggaaatgat aaagttgcta acatgataat gttaggcgct tacttaaaag tatctgatac
     8521 tgtagatata gaatctgtac tagaagcatt caaaaaagtt ttcggaccta gaaaagaaaa
     8581 attcgttcca ttaaacagag aagctttaca aaaaggtatg gatgctacat gttctaaagc
     8641 aactaactaa taaagaaaaa gatgtcaaaa aaaagacaat agaattattt ctattgtctt
     8701 ttttgctgat aagtattaaa atatttttat gactgaaatt aagcctataa tgatatttta
     8761 tgaactataa aaatataata caaattacaa gcttttcaat tatgaaagga gaatctttag
     8821 tgagaaagta ttttggaaca gatggagtta gaggagtagc aaatacagaa ctaacatgtg
     8881 atttagcata taaacttggt agagctggtg gatttgtctt agctcaagga gaccacagag
     8941 taaaagtagt agtaggtaag gatactagaa tatcaggtga tatgttggaa gcatctttaa
     9001 tagcaggact tatgtctgtt ggatgtgatg ttattactgt tggaataata ccaacacctg
     9061 cagtggcata tttaactaga aaatatggtg ctgattgtgg tgtggttata tctgcatctc
     9121 acaatcctgt tgaatataat ggaatcaaat tctttaataa gaatggatat aaattagatg
     9181 atgaaattga attgaaaata gaagaatata tagacgatat agacaaaatt gattgtcttc
     9241 caattggtga aaatgtagga agaaaattac atgaacattg tgcacaaaga gactatgtag
     9301 actacctaaa atcaataata agcactgact ttaagggatt aaaagtagtt ttggactgtg
     9361 ctaatggtgc gtcatataaa gtggcaccaa tagtgtttga tgaactagga gcaagtgtaa
     9421 tttcaataaa tagttcacca gatggaaata atataaacta taaatgtggc tctacacatc
     9481 cagaacaact tcaaagggct gttttggaac ataatgctga cttaggtctt gcatatgatg
     9541 gagatgctga tagattaatt gcagtaaatg aaaagggtca aattgttgat ggagaccata
     9601 taatgatatt gagtgcctta aatttaaaga aaaataataa attggcacaa gatactttgg
     9661 tagttacagt tatgagtaat atagggttga caatagctgc taaggaaaat ggaataaatt
     9721 tatctactac agcagttgga gacagatatg ttttagaaga tatggttaaa aatggatata
     9781 atcttggtgg agagcaatct ggacatatga tatttttaga ttacaacact actggagatg
     9841 gagtgcttag ttctctaata cttgcaaata taatcttgca agaaaagaaa cctttatcag
     9901 aaattgcatc aataatgagc caatacccac aagtattagt aaatgcaaca ataaaaaatg
     9961 aaaataagaa caaatatatg gaatatccag aaataaaaac tgagatagaa agaatagaat
    10021 ctattttaga cggaaatggt agagttttga taagaccatc aggaactgag ccattagtta
    10081 gagttatgtt agagggtaaa gaggaaggtc aaataaaaga attagcaaca aacttagcta
    10141 atcttataca agaaaaatta tcgtaattta aagggtattc tcagatataa atactgagga
    10201 cacctttcta agcgccagaa cttagttata gacataatta ttgagtaata taggaactaa
    10261 gttgacgagg tcagagttaa tcgaattgtc ggcggatgct ctgcggtgtg tttaccatcg
    10321 aaagacttct ttaaataata ggagcaatcc tatggacaaa gggaagccaa agtaaactta
    10381 tatgacctaa ctcttaaaat atataaataa tatttttagg aggacacaaa taatgtgtgg
    10441 aatagttgga tatttaggaa gtagaaaggc agcagaagtt atagtagaag ggctttctaa
    10501 gctagagtac agaggttatg actcagcagg agtagcagtt aatagttcta atgaaaaaga
    10561 acttaatatt agaaagttta aaggtagact ttctgtactt gcagaagact tagaaaagaa
    10621 tcctattgat ggaaatttag gtatagggca tacgagatgg gcaactcatg gagaaccatc
    10681 tgatgtaaac tcacatcctc attttaatca agccaaaaca atagcagttg ttcataatgg
    10741 gataatagaa aactatatgg aaataaaaga agaattaatt tctgaaggtg ttaagtttga
    10801 atctcaaaca gatacagagg taatagcaca tttagtagat aaatactatg agggtaattt
    10861 attagatgct gtatacaaaa ctatatcaaa attaagagga gcttatgcat taggtgttat
    10921 atgtaaagaa catggaaatg aattagttgc agtaagaaaa gatagtcctc ttgtagttgg
    10981 tgttggtgaa ggtgaaaact ttatagcatc agatatacct gcattattaa aatatactag
    11041 agatgtttat ttcttagaaa atggagaagt agttcatcta aaagacgaaa atgtaacagt
    11101 ttatgactct aatagaaatc ttgttgaaaa agaagtattt catgtaactt gggatgtaga
    11161 agctgcgtct aaaggtggat atgactactt tatgtcaaaa gaaattcatg agcaaccaac
    11221 aggagtaaga gaaactttag aaagaagact tgatgataat ggaaatataa ttctagacag
    11281 tataaatatt tctaaagaag acttagaaaa aataaataaa gtttatatag tggcttgtgg
    11341 aacagcatat aatgctggat tacttggtaa gtatgccata gaaaaatttg taaatatacc
    11401 agtaataact gatatagcat cagaatttag atatagcgac ccatttgtag atgaaaattc
    11461 attagtaata ttagttagtc aatctggtga gacagcagat actctagcag tattaagaga
    11521 ttcaaaggct aaaggagcaa gaatactttc aataactaac gttgtaggtt catctatagc
    11581 aagagaatca gatgatgtat tctatacttg ggcaggacct gaagtagcag ttgcatcaac
    11641 taaggcatat actactcaaa taacttcttt atacatgata gctttagact ttgctatcaa
    11701 aaaaggaaca ataactagag aattttatga tagtatgatt tctaagatga aagaaatacc
    11761 atcaaaaata caagaaatac tagacaatga agaatatata aaagaagttg ctaaaacagt
    11821 tgttagttct gaacatgcat tctatttagg aagaggtata gactatagct tagcaatgga
    11881 aggttcattg aaattaaaag agatttcata tatacatgca gaagcttttg cagcaggaga
    11941 gctaaagcat ggaacaatag ctttaataga aaaaggaact ccagtaattg ccatagctac
    12001 tcaagaaaag ttatttgaaa aaatggtttc taatatggaa gaagtaagag caagaggagc
    12061 ttatgtagta gcaatagctc aaagccataa taaggatgtt gagaaagctg ctgataaaat
    12121 aatctatata ccaaattcag atgatatttt atcaccaata ttagcagttg taccaatgca
    12181 attacttgct tatcatgtct ctgtactaag aggatgcgat gtagataagc caagaaatct
    12241 agctaaatca gtaacagttg aataaaaaca gattaaaaat taaatagata atatttattg
    12301 aaaagaactc atcctgttat ttgtatttta taggatgagt tttttagata aatattaaat
    12361 ttgttttgtt tttgctataa taaattttat aaaaagattg atattaaatc atctgtaaaa
    12421 tgataaatat atagaccata ccaggtatag ggaacgataa atatagttca tataaaatat
    12481 agtgagtact taataaacat atagtcaata tcagataaaa aaaataatag cttatgagaa
    12541 aaattaaaat acaaggtatt agtaaccttg tgataagata aagtgagtag tttaaaataa
    12601 gaatataagg aactatttat aaaagaatat aatgaagcta atagagtata agaaaattac
    12661 tttattttag taaaataatt tcaaataaaa atttttttaa attgggagta taaattatga
    12721 caaatgattt taaaaaagaa aagaaagaag attattttgt taatcttaag gcaatatcta
    12781 ctgaagtttt acaagaaaaa gtgcaagata acgcttgggt tatagttgat actcgcttaa
    12841 atgatgctta taatggctgg aagttagatg gagtaaaaag aggtggacat ataaaaggag
    12901 cagtagattt ttctgctaat tggttaagtg tatactcaga tagaaaagat gaagtgttag
    12961 aacaagcatt gaaaactaaa agaattgatt tagataaaaa tatagtattg tatgatgcaa
    13021 atggaaaaga tgctttggtt gtagcagatt atttatctaa aaaaggatat aaatatctat
    13081 ataaatatga tattaaacaa tgggcagacg acgaaaatct tccaatggaa agatataaaa
    13141 attatcaaat gatagttcct gcttttataa taaaagatat attagatgga aaaatttctg
    13201 agacatttga agattcaaag aatataaaaa tgattgaagc gagttgggga gaagaatcgt
    13261 atacaaaagg gcatatacct acaagtgttc atgtaaatac tgatattata gaacctcctc
    13321 caacatggat gcttgataat gatgataact taactaagtt tgctttagac tatggattaa
    13381 caaaggatga tactgtaata gtttcaagta gtacacctat ggcatcttat agactagctg
    13441 ttatattgag gtatatagga gtaaaagatg taagagtttt gaatggtgga acaaactcat
    13501 ggttatcagc aggatatgaa ttagaattta ttagtaatcc aaaacattca tgtactaatt
    13561 ttggagcaga tataccagtt aactcacaat taattgttac tacatctgaa ttaagacaaa
    13621 aactaaaaga aaaaaataag tttatactag tagataaccg tacttgggat gaacatatag
    13681 gaaaagtatc tggatataca tattatgata aaaaagggcg tataccagga gctttatatg
    13741 gacattcagg tagtgatagt gtttcactag aagaatatcg taatattgat aatacaatga
    13801 gaaataaata tgagatttta gaaatgtggg acaaggaaaa tatagatgtg aataaacagc
    13861 ttatatttat gtgtggaagt ggatggcgtg ctgctgaagt attaacatat gcaaatgtca
    13921 taggagtgga aaatacctcc ctttatagtg atggatggat gggctggagt cttgataatt
    13981 caaatttaat tgaagtggga gaacacaaat aaagtttttg aaagtgcaat agagttgttt
    14041 aaaacaaagg tgtttttgat ttattaggaa gagtgtgtaa attgtgtatt gggaagtgta
    14101 cttaggtatg ttcatttgga gctatggaaa ttgataaaaa agtattatct gtttattttg
    14161 ttggtaaaat atgaatagat tatagattat agattataga ttatagatta tagattatag
    14221 attatagatt atagatttaa gtatagacta agtaatttat attacagaag agaatatata
    14281 agaattaatg caagatgtat ttgatacata taagaaattg gcaagtccag gagaaggata
    14341 gagaaaattg agattgaaga gtttgaaaga gattattaga tgaaaaatac aaaaatgtat
    14401 aaaaatacat attgagaaag tatatctctc ttaaatttgt taataattct attatacaga
    14461 aaaacatatt taagggggat tttttactat gaaaaaagta aaattagcta taagcttttt
    14521 tatattaatg attataggaa tgacaatatc ttatgcagat acaagtataa atactagata
    14581 caatagatta agtaaagctc ttgaaatatc agaagcaaat tttaaatttt ataatgttaa
    14641 aattaattct gttataaatc ataatttatc aaataaagaa tttcataata tttttataga
    14701 aataattaac aatctaaagt tggataaaaa aggaataaat tggaatcaaa aagggtctgg
    14761 cgataaaata caattatgtg ctactataaa aggtagcgat aaagaaattt ctataaaagg
    14821 aataaataaa aataacaaag aaagttacat agtagttgac atattggata acaaagtata
    14881 taaacataaa gaggttattt atagtaacgt agaaaatgtg ttaaataaat attcatctca
    14941 agtagatgtg tctgcttgta ttgttggaga atacacaaaa aggttacaaa acaacaaata
    15001 tgatgatatt ttacaaaaaa tattatataa tatgagtgct aagcaaatag atgaagttaa
    15061 agacgtaaac tttttatcta taacagcata tagtaaagta ttaaatgatt atgaattaga
    15121 atatttaggg gaaaaaatta atttaaatat aggaattaaa tataatgagg atgacggaaa
    15181 aacactcata tatattgcca caccaattat aaaattagat tattaattat gaggagatca
    15241 aaaaatatgg ctaagataat agtaaaaaag agtaatccac ttaaaggtag tgttaaaata
    15301 gatggtgcaa aaaatgcagt tttaccaata atagcagcga ctttattagc aaacggaaaa
    15361 tcaacattaa atggagtacc aaatttaaga gatgttcatg ttatatcaga tttattaaga
    15421 catgtaggag cagaagttga atataaagaa aatacactta ctgttgatgc aagcaatata
    15481 aaaacttgtg aagctccata tgagcttgta agaaagatga gagcttcttt tttggttatg
    15541 ggaccattgc ttgctagatt taatagtacg aaaatttcta tgccaggagg atgtgctata
    15601 ggaacaagac ctatagattt acatttaaaa ggatttaaag ctttaggtgc aaagatagaa
    15661 atggaccatg gttttgttga agcagcaaca gaaaagttag taggaaataa attatattta
    15721 gatttcccat ctgttggagc aactgaaaac ataatgatgg cagcttcttt agcagaaggg
    15781 actacaataa tagagaatgc agcagaagag ccagaaatag tagatttagc aaacttcttg
    15841 aacgaaatgg gagcagatgt taaaggtgca ggtactaata ctataaaaat aaaaggtgtt
    15901 aaagagttaa aaggagcaga acataatgta attccagaca gaatagaagc agcaacttat
    15961 atggttgcag cagctatgac aaaaggtgat ataactgttg aaaatgtttt aatggagcat
    16021 ttaaaaccag ttgtagctaa attaagagaa gctggttgtg aaataacaga aatggacaat
    16081 tctgtaagag ttgtaggtcc aaaagtatta aaaccaatag atataaaaac tttaccacat
    16141 ccaggatttc ctacagatgt tcaagcacaa tttatggcta tgcttactgt agccaatgga
    16201 actggtgtag ttatagaaac tgtttttgaa aacagattta tgcatgttgc tgaatttaat
    16261 agaatgggtg ctaatataaa aatagatgga agaagtgcgg ttgttaatgg tgtagatgag
    16321 ctacacggtg cagcagtaaa cgctactgat ttaagagcag gggcagccct tattttatgc
    16381 ggtcttatag cagaaggaga aactcaaata ggagaaatat accatatcca aagaggttat
    16441 gttgatatag ataagaagat aacagcacta ggtggtcaaa tcgaaatagt agaagattaa
    16501 taattggttt atagaagaaa gttataaatt aatagggttg ttcatatact taaatacaag
    16561 gttttaaaag ctaaggagga gagtatatga agaacccatt ggttgttttg ttaggatttg
    16621 tgacttgctc tgtgttagtt ccatcactta taactttagt ttcttataaa aatgtagaat
    16681 taactgaaaa accagagagc ccagtatcta taaacaaaac tattaaaaaa agtgatattg
    16741 aagacaaagg taataaagaa gaaaaaaata cagtgaacta tgaaactgta aataaaaaag
    16801 caccaattat caatgtatat aatcatataa cagggaaaac cgaaaagatg gacatggaga
    16861 actatttatg tggagtacta gctggtgaga tgtcttcaga gtttgatata gaagctttaa
    16921 aagctcaatc tgtagcagct agaacatatg tagtatataa acaggaacat ggtaaatcta
    16981 gtaaacataa aaatgcagta gtatgtactg attataaaca ttgtcaagaa tataagagtt
    17041 atgatactct taaaaaatta aatggtgaag aatggattaa gaataaatat tccaaaatcc
    17101 aagaagcagt tagaggaact aaaggtcaaa taataactta taatgataag gcgatacttc
    17161 ctctttattt ttctacatct tcaggaaaaa cagaaaatag tgaagaagta ttttctgcaa
    17221 aatatcctta tttaaagtct gtggaaagtc cttatgataa gtattcccct aaatttgcgt
    17281 caacacttaa aataagtaac acagattttg ttaaaagtct tagaagggca tatagcacta
    17341 ttgtgataga tgtgaataat ttaagtaaac aagtttcaat aactaaaaga agtgatgccg
    17401 gaactgtaga aaaaataaaa ttaggaaata aagaattgac tggaaaagac attagaactg
    17461 tttttaaatt gaactctgca aactttgaca taaaatttgg agaaggatac atagatttcg
    17521 tggtaaaagg atatggtcat ggtgttggta tgagccagtg gggagcagaa ggaatggcag
    17581 aagagggcta taaatattat gatatattat cacattacta cacagataca aaaataaaag
    17641 atatatacta ataattgtat aaaatgccaa aaacacgtca ataatccaaa tgtagaaata
    17701 tatttggagg tgcaaaatga agaaaaagct gttagaaaaa gatggttttt atttatcttt
    17761 gtttgtatgt gtttgtttat tagcagtagg tggagtttgg tttacaaata ataatgtaga
    17821 taaattggct tctaataaag gaattatgga aaatgctaat aaagatagtg aagaggaaat
    17881 acatttaatt gaaaaagaca agaaagatgc tatccctact gcaacggatt caaaacaaaa
    17941 cttagaaaaa gctaagtcaa aagaggaaaa taaatcgagt acaacaaaat taaattacat
    18001 tggagataaa gtaataagag gatattcaga aaaagagcct agttattcta aaacacttga
    18061 tgtttgggaa actcataaag gtgtagatat tagttgtact aaaggcaaag aagtaaaatc
    18121 tctattaaac ggaatagtag tagatgtatt tgatgatgaa gaatatggac aatcagtcaa
    18181 aataaaaagt gacaataaca ttgtagtagt atattcaaat ctagataaaa atgttagtgt
    18241 taagaaagaa cagaaggtaa cagaaggaca atctctaggt actgtaggta gtacttctca
    18301 aatagaaagt gaagaaggta tacatgtgca tttagaggcg tatagtggag aaaaatctat
    18361 agacccaatg agtctaatta agtaatagta taacaagttt aatcatattt ggttaagctt
    18421 gttatatttt ttggtgtttt tacatatata tcattaaagc tattatgtga ggggggtaat
    18481 ctttgagatc tcatatagag gaaagggcca tagtggtagc aaaatatata cttgaaaaaa
    18541 acactacagt aagacaaacc gccaagacat ttggagtaag taaaagtaca attcataagg
    18601 atgttacaga aagattgaag gaaataaatc catcccttgc caaagaagtt aaaaatgtgc
    18661 tggacaaaaa taaatcagag agacatatta gagggggatt agcaacgaaa ttaaaatatg
    18721 agaaggaaca taaaaaaatg taggttaaaa acctactttt tttattgaat taaattataa
    18781 aaagaaatat attaagtaat tataaatagc aaaataataa tactctcaaa agatttattt
    18841 tctcttgatt aaagcgagat ttttgtatat gctttattat aggagtatta aaataggctt
    18901 ataatataat ctaatattat aaataaagga gttgaaaaaa tggctggagc tgatataggc
    18961 atagatttag gtactgcaaa tgtgcttgtt tatgttagtg gtaagggaat cgttttagaa
    19021 gaaccatctg ttgtggcgat agacaaaaga acagattctg ttttagctgt gggagaagaa
    19081 gctaaaaaga tgatagggag aacaccaggt aatatagtcg ctataagacc tttaagagat
    19141 ggtgtaattt cagattatga tgtaactgag aagatgttaa aatcttttat agataagata
    19201 gttgataaaa agggatttgg aagatttttt atgccaagaa ttatggtatg tgtaccaaca
    19261 ggtgtcacag aagtggaaaa aagagcagta gaagatgcta cgagacaagc tggagctaga
    19321 gaagtatata tcatagaaga accaatagca gctgccatag gagctggtgt agacatatca
    19381 cagcctaatg gtaatatgat tatagatatt ggtggaggta ctgtagatat agctgtaata
    19441 tctctaggag gagctgttgt aagtgaatct ataaaggttg gtggagatag atttgatgat
    19501 gctatagtta aatatatgaa aaaacaacac aatcttctta taggagaaag aacagcagag
    19561 aaaatcaagt ttgaaatagg ttctgcattt aagagagaag aagaaaaata tatgaagata
    19621 acaggaagaa atttaattac aggacttcct agttctataa ctataaattc aacagaaatg
    19681 ttggaagcac ttagagaatg tgttgagcaa atagtagttg ctactcatgc tgttttggaa
    19741 aaaacgcctc ctgagttagc agcagatata ggagatgtcg gtataataat gactggagga
    19801 ggttcattat tatatggatt agataaaata atagaacaga ggacaggaat aactgttaca
    19861 atagcagatg aaccattatc ttgtgttgca aaaggtacag gaatagcttt aggttcaata
    19921 gacttacttg aaactggtgg gtctttcaaa agaaaataat taggagagtt tagaatgtta
    19981 aatatagatg aaataaaaaa attaatacca catagatatc catttttatt agtagacaag
    20041 attacagagc tagaagttgg gaaaagagct gttggtataa agaatgtaac agttaatgag
    20101 ccatttttcc aaggtcactt tccagaatat cctttgatgc caggagtact aatagtagaa
    20161 gctctagcac aagtatgtgg agtggcaatg atgtctgtag aggaaaacaa aggaaaacta
    20221 ggtgtatttg caggtataga taaagttaga atcaagagag aagtaagacc aggagataca
    20281 ttaactatgg aagttgaaat gacaactctt agaaaaaata tagctaaggc agatgctaag
    20341 gcatatgtag gtgaagaact tgtctgtaaa ggtgaattaa tgtttgcttt agtagaaaaa
    20401 taaaaacttg aaatataaaa gtaaaaaggt agataatttg gagtatttaa tcagatactc
    20461 taaaatatct acctttttat ataaagaatt ttatcattta gtttatattt agattaggtg
    20521 gatactaata aagccaaggc tattgtttca gctaaatcta atataaagct aaggcgtata
    20581 ttattaaatg aaagtttatt attttcatca attttatcta caattcctac tatagaataa
    20641 tttcctattt gaggtagttt tttaccaaca ccttttccgg gcaggatagg tccttctcta
    20701 atctgtatat tacctatgtt actctgcgac cccaagcaag catctatagc caagaagtta
    20761 ccttgtatat gtgtattttt tatagtatct aaagactcat atatatttaa ggcgtgaata
    20821 gggttatcta gtgtaccgta aacggggtat ttaaagttac tgttcttaag tattgttcca
    20881 actaaagggc ctaaagtatc acctatagcc ctgtctgttc ctatgcaaac aacaatcgta
    20941 ttttcattaa ttatagtttt tagaactgaa cttagcatct gtataacatc atcatcgctg
    21001 tagtttactt tagctaaata caataggaac acccccttca aaaaaatata tgaataaaaa
    21061 gcattaaaaa gacctaactt taaatttcag atagatagaa aattttattt gtcttacaaa
    21121 aaaaggaata gaaaaaatat gactaaaaat attgacaaaa ttttaaaaaa atagtaagct
    21181 agtaaagtaa aacaaaactt aaatcttgat taccttatca agagaggctg agggataggc
    21241 cctgtgaagc ccagcaacca cccaaatggg aaaaggtgct aattcctaca agacaaaagt
    21301 cttgaaagat gaggtcagtt aattagtatg taattacgat tattaacctc ttcttataaa
    21361 ggagaggttt ttttattttg agtaaatttc taaaattaaa aataaggtaa aacctataat
    21421 aaaaattaag aataaataag ggggaataaa aatggcaaga catttattta cgtcagaatc
    21481 agttacagaa ggacatcctg ataagatatg tgaccaaata tcagattcaa tattagatgc
    21541 attattagaa aaagacccac aatctagagt agcttgtgaa actacagtta ctactggttt
    21601 agttttagta gcaggagaaa taagtacatc tgcttatgta gacattccta aattagtaag
    21661 agaaacagta agagaaattg gatatacaag agcaaaatat ggatttgatt gtgatacttg
    21721 cgcagttata acttctattg atgaacaatc tggagatata gctatgggag ttgatgaagg
    21781 tctagaaagt aagactggag aagagataga agaagaaata gaaaaagttg gagctggaga
    21841 ccaaggtata atgtttggat ttgcatgtaa tgagactcca gaattaatgc cacttccgat
    21901 atctttggca cataaattat caagaagact tacagaagtt agaaaaacag gtttagttga
    21961 ttatttaaga ccagatggaa aaactcaagt tactgttgaa tatgaaggaa gtaaagctgt
    22021 aagagtacat acagttctta tatcagctca acattgtgaa acagtatcaa atgataaaat
    22081 aagagaagat ttaattaatc atgttattaa ggaagttata ccagcagaat tacttgatga
    22141 agagactaaa atttatataa atccaacagg aagattcgtt ataggaggac cacaaggaga
    22201 tacaggtctt acaggaagaa aaataataat agatacttat ggtggatatt ctagacatgg
    22261 tggaggagct ttctcaggaa aagaccctac aaaagttgat agatctgctg cttatgcagc
    22321 tagatatgtt gcaaaaaata ttgttgcggc tggtcttgca gacaaatgtg agatagaact
    22381 tgcatatgct ataggtatag ctagaccatt atctatattt atagatactt ttgggacagg
    22441 caaggtttca gaagaaaaac ttgttgaatt agtaaataaa cactttgatt taagaccggg
    22501 agcgataata agagacttag atttaagaaa gcctctttat aaaaaggttg ctgcttatgg
    22561 tcactttggt agaactgata tagatttacc ttgggaaaga actgacaagg ttgagcagtt
    22621 aagaaaagat gctttaggtg aataattttt aactaaaaag ctgttagaat gtaattttat
    22681 gattactttc taacagcttt tttattatga gttaaatatt tttaataaat gttaatttat
    22741 catcatataa tgaataaaca gtatttaatc tggtcaatac attttatata atactctact
    22801 aaatttatac atattatggg atatatgtta aaggatggtt aagaatgtgt taactaatgt
    22861 taaataatta aaaatatatt gaaatatcac aataatgagt ctaatataat cttaataaac
    22921 ttacacttta aaaataattt taattggggg ggagtagtgt atgtcaggca aagtaaatat
    22981 taaaacggtt ataagttttg ctggagctta tgttgctact gtaataggtt ctggatttgc
    23041 aactggtcaa gaaatactgc aattttttac gttttatgga tatgcgggta ttataggtgg
    23101 aataatctct atggtactat tttcatggtt tggagcagaa gttatagata agggaagaga
    23161 attgaaactt aaggagccaa taaaaattta tcaagtatat tgtggaaaat atcttggaac
    23221 attttttgaa tggtttggtc cattgttttt atttggaaca ttagtaataa tgattgcagg
    23281 agcaggagct acattatcag agtactatgg attaaatcca tatgtaggta ggattggtat
    23341 ggcaatcgtt tccctaataa ctgtttcatt aggtttgaca aggctttcta aaatactagg
    23401 taatatagga cctataataa taatatttac acttttagta ggagcaatta gtttatttag
    23461 caatattgat gctttatcaa atgctggaaa tatggttgat agtttaaata ttaaaactgc
    23521 tacatcaaat ggatatttct cgggagtact ttatacttgt tacaatgtaa taatagtaat
    23581 aacattcttg acaggaatgg gagcttctgc agtaaataag aaagatgctg tatggggtgg
    23641 tatagtaggt ggagtagcac ttatggcagc agctataatg atgaatttgg cattactttc
    23701 agacatagga aatatataca caaaagagat accagcactt tacttagctg ataagatatc
    23761 tccaataata ggtattttat tctcagtagt acttttacta ggaatataca ctacagctgt
    23821 accattgtta tggtcagtaa caaaccgatt tgtagaagat gaccacccta agtttaaaat
    23881 tataacaata gtggtaagta tattagcttg tataggaggt ttactgccat ttgataagtt
    23941 agtaggtaca ctatatccat atacaggtta catgggaatt ttaattttac tatgtatgct
    24001 ttatagaaga attactaaaa ctgaggggta caaggagaat aaatctgaaa taagttagta
    24061 ctgtaatata cttatgaaat ttaatttata ctctaaatat agagtaatta aaataaaata
    24121 gctatttaaa tatggtacct gtatttcatg gtaccatatt ttatggatgc agattttttt
    24181 tgtttctgat aaaatgtata atagttggaa attacgttaa gtataaaaat ataaaacttt
    24241 tctacgatta tcatagtttt aatatataaa attatactaa catttaaatg gagcgattat
    24301 tagtattttt aggagataaa aatggaaaaa ttagaaggaa tgataagtga aatagtcttt
    24361 aaaaacgaag ataatggtta tacaatagct cacctggtaa atgaaaatga tgaaattgtg
    24421 gttgtaggat gtatgcctac tttggcaatt ggagaaagca tagaagttga aggaaagtgg
    24481 gtaaatcata agatttatgg gactcaattt gaagtgaata gttttatgcc agtaacacca
    24541 tcatccttag aaggaattta tgtttactta tcttctggaa tgatacatgg tattggtgaa
    24601 aaaatggcaa aaagaataat tgataagttt ggtgtagata cgttagaggt gatacaaaat
    24661 tcaccagaaa aactacaaga agtagaaggt atagggagta aaaaagtaaa acaaatagta
    24721 aaaagttatg aagaagacag agaattgaga aatataataa tacagctatc tccttttgga
    24781 ataacaccaa attactgcct aaaaatatat aaaaaatata aaagcagtgc aatagaagtt
    24841 ataaataaaa acccatacca acttgctgaa gatataagag gaattggatt taaagtagct
    24901 gatagtatag caagtaaaat tggtatagat aaaaactcta aagatagaat ttgtcaggga
    24961 atcttataca ctttaaataa atctttaagt aatgggcata catatttacc agagcatgtt
    25021 ctaatacaag attcggaaaa attgttggag ctaaatggag aaatactaaa agagtgtgta
    25081 atgatgctag tttataatca aaaaatacat atagagaaag taaacaatga aaatcttata
    25141 taccttatgc catactattt agctgaaaat ggagtatgta gtcaaatagt aaaattatca
    25201 cagtatgaat ttgaagactt aaaaatagat atagataacg agattaatgt tttagaagaa
    25261 gataagaaaa ttaagttagc agaaaaacaa attttagcag tcaaagaatc tgttaatagt
    25321 ggagtattaa ttataactgg tggaccagga actggtaaaa caactaccat taatgctatc
    25381 atagatatat ttgaaaataa tggtaaaagt gtgactttgg cagctccaac gggaagagca
    25441 gcaaagagaa tgagtgaaac ttctaataaa gaagcaaaaa ctatacatag gttgctagaa
    25501 atgggatttt caacagatga tgatttaact ttttttaagg atgaagaaga cccaataaat
    25561 tcagatgtaa taattgttga tgaggtatca atggtagaca ttatcttaat gtacaattta
    25621 cttagagcta taaagttagg aacaagagta attttagttg gagatagtga ccaattacct
    25681 tctgtaggtg ctggaaatgt acttaaggat atgattaatt ctaatattat aaatgtagtt
    25741 aaattaaatg aaatatttag acaagcgcaa gaaagtatga taattgtaaa tgcccataag
    25801 ataaacaatg gagaaccact ttatctaaat acaaaaggta aagatttctt ttttataaga
    25861 aaatcaacta atgaagaaat tttaaatgaa ataataggat tggttaatga aagattacct
    25921 aaattttata aagttgataa attaaaagat atacaagttt tatcttcaat gagaaaaggt
    25981 gaattgggag ttactaatct caatatagag ttacagaagt atcttaacaa aaaagaaaaa
    26041 tttaaagttg aagaaagttt ttctaaaaga ttatttagag ttggcgataa ggtaatgcaa
    26101 gtaaaaaata attatacaaa aaaatgggaa acagaagacc aaaaagaaag tggagaaggt
    26161 atctataatg gagatatagg atatgtttat cacatagata aagataagaa aactatttat
    26221 atattatttg accagactaa aattgtatca tacctatatg atgaattaga tgaaattgac
    26281 catagttttt gtacaacaat acataaaagc cagggaagtg aatttccagt tgtagtattg
    26341 ccaatagcgt gggctcctcc tatgttactt agccgtaatt tattatatac agcagtaaca
    26401 agagcaaaaa aattagttgt attagttgga gatgtgaaat atcttgaata tatgataaaa
    26461 aataatagag ttaatcaaag gtattcaaat ttaggatata agctaaataa atttaaacaa
    26521 gaagggttgt tgatagaata aatatgaaaa tatgcaatga taattttatt aagaatttta
    26581 aaaatatgat taataaatgt ttggatttta tatatcctga gaatataagt tgcataattt
    26641 gtgataaatc cataaagaaa acaaatactt attcaatatg taaaagttgt tttaaagaaa
    26701 tgaattttat acaagatggt tgcatgaagt gtggaaaacc aataatacgt cattcaattg
    26761 aaaaagaatt tattgaagag tgtagttatt gttttaataa agacttttat tttgataaat
    26821 caatatcttg tattgaatac aatgatgtga caaaaaagat ggtgttaggg ctgaagtata
    26881 accaaaaaac ctttatggct aagtatatag ctcaaataat gaaagaaaaa ttatatttag
    26941 aaaacataaa atttgattat atattatttg ttccacttca taaaaaaagg ctaaataaaa
    27001 gaggttttaa tcaggcacaa aaaatagcat ttaatttaag taaaatagta aatattccat
    27061 tattagattg cataagtaga aaaaaatata caagaatgct atataaattg aataagaaag
    27121 aacgaaaaga agaattaaaa aatgtatttg ttgttaaaga aaatgttaaa ttaataaata
    27181 ataaaaatat acttttaata gatgatatat ttactactgg tctaacaaca aacgaaattt
    27241 ctaaactttt aaagttatca ggtgctaata aggtttttgt attgactcta cttacaaaag
    27301 caaatgataa ttatattatg gaataatctt atatattgac aattttagtt taaaatatta
    27361 aaatgaataa gtgatattta ggtctgtggt tgaaagtcca agccagtcgc aggcaaaggg
    27421 atccacgtaa gttaacacta aaaattgggt taatgatcat ggtgcggctt agaagtaaga
    27481 cctaccgata ataaaatcga gagagagtag tagtgcggcg aacccaagcg aaccctccag
    27541 taggcgagtg tggggtcaaa aaccaggtca gctaaatatc atattaaaag agagctagca
    27601 tacctttatg tatagctctt ttttatatat aataaattta gtttgagtca taaagaggtg
    27661 atatgtttga ataaaagaca agaaaattta ttaacaacat tgctattaaa agaagagttt
    27721 ataaatgtta ataagattgc caatgatttt gagtgttcag aaaggacaat aagaaatgat
    27781 tgcaaatata ttgatgaatg gttatctact ttttgtaatg cttatatcaa aagaaaacct
    27841 aatattggga ttaaatttag tggagatgga acagacaaaa tactggtaaa tcagaagttg
    27901 cgaggtgaag ttaaaagagt aaatagtgag cttcataagc aagttgagat attaaattta
    27961 ctactttgta ataataaaaa agttacttta aatgatttat ctaataagtt gtacataaat
    28021 aaaaatattg tcagagaaga aataagtaaa ttatcagtag cattaaataa ttataattta
    28081 aatatctcga ctaaaaaagg cagtggtata tatattgaag gggatgagaa agacataaga
    28141 ataatgttag tatcattctt atttaaatat atagataaat acagattaaa catagatgaa
    28201 atagagtact tccatatagt agatataata attgtaaaaa acataatgct tactatagag
    28261 gaggatatgg atataagact tacagatata tcattcaagc aattgatgct atttttgctt
    28321 ataaatataa tacgaataag gctgggaaat tctttaaaag tatcaaatac taagaaagag
    28381 cttaagctaa aaatgcttat attggatata gaagatgaat tgaaatctaa tttatccata
    28441 gtattaaatt atgaagaaaa attgtttata gaatctttaa tattgggtat gaacaaacaa
    28501 ataaatagta ataatattaa gaaatcttta tatctaaatg aagaattagc aagttataca
    28561 aaaaaaatta taaatttagt atcagaagaa tcaggaataa attttaataa tgatatatta
    28621 ctttatgaac aattaatatg tcatttgaat gttacaatgc atcaaatgaa aagcaatgtt
    28681 tacttagaaa atccactttt agataacata aaaactaaat tttgtttttt atttacagta
    28741 atatcaagtt caatagaaat tgaattaaaa ggaaaacaaa taacggaaga tgaaattggt
    28801 tatcttacac ttcactttca aacctctcta gaaagaaaat acagcaaaag ggaatcaaat
    28861 aaaaaggcaa gtattgtatg tccatttagt tttggagtaa gtatgctatt aaaagtaaag
    28921 atagaaaaga gatttgataa cataaaaatt attgaaacat taagagagga agatttaaaa
    28981 agagataact ttaataagac tatagatttt ataattgcat ttcaagagta tgaaaatatc
    29041 caaaaaccaa tttttataac aacaccatta tttactgatg aggatgagaa taaacttaaa
    29101 gagttcacaa acaaaataaa agaaaaagac acttcatata aacttatgaa cagattaatg
    29161 atgtctgatt atttaataag agagttagaa catgatgata tttatgaagc tataacatat
    29221 ttaactaatt tattaattga aaaacattat gcagaaaaag agtatttaca atctattata
    29281 acaagagaaa agtcatatcc aaccaatgtt ggaaaaggaa tattattccc tcatggagac
    29341 atgaaatata taaaacaatc tgttttatgt tttgcaaggt taaaaacacc aataaaaatt
    29401 agaaatggaa aggatataaa gattatactt ttgttagcat ataaaaaaga tgatgataga
    29461 aaagtattta gagaattatt taaagaaata tctaatttaa cagaggatga aaatatgcta
    29521 gatattctaa gtaaatgtga cattgaaaag gtaaaagata ttcttatata aaattcatag
    29581 tgaactatgg ataagcacaa aattttccat gtgatggaaa aagttgtgca tgtttttttg
    29641 tttttataag atattatatg tttgtaaggt ataaataatc taaaagtaga gaagcaactt
    29701 aggaggaaaa aatggaagaa atagttttaa agattataat tcatgctgga aatgcaaaat
    29761 ctatgcttta tgaagcactt gactatgcaa aggaaaacga ttttaaaaaa gcagatgaat
    29821 taattgaaaa tgcaaatgaa gaaattttaa aagcacataa agtacaaact gaacttatac
    29881 aaaaggaagc tgggggagat aaatcagata tatctatttt attgattcac tctcaagacc
    29941 atttaatgac ttgtatgagt gagagaaacc ttataaaaga aatgattatg ttaagaaaag
    30001 aaattcaaaa attaaaataa aaaaattaag ggggatttaa aaaatgaaaa gaaaagtata
    30061 tttattttgt agctttggta tgtcaacaag tttacttgca gataaaatgc agaaggtagc
    30121 agatgaacac aatttaccaa tagaagtaga ggcatttccg atagcagaaa ttgacaaaat
    30181 agttgaagaa aaaaatccag attgtatatt attaggacca caagttaaat acatgctaaa
    30241 ggagttaaaa ccaaagtttg aagctcaagg aaaacttata gatataatca atgaagttga
    30301 ttatggaact atgaatgggg aaaaagtatt aaaacttgct ataaagctaa taaaatctaa
    30361 acaagcgtag aattatagta aaaaataata ggaaatgagg gtggatagat gaatagattg
    30421 gaaagaatac ttatgccatt ggctgaaaaa ataggtaaaa ataaattatt aattgcaatt
    30481 agagatggtt ttttagtatc atcaccatta ttaataatag gttcattatt tttattagta
    30541 gcaaattttc ctataaaagg atggaatgaa tttgtaggtc aaatttttgg tccagattgg
    30601 gctgtaaaat tgcaacaacc aactgtagca acatttgaag taatgactct acttgcagtt
    30661 ttagggattg gatattctta tgcaaagcaa atagatgtag acccaatagc atcagcagca
    30721 gttgcaatag ttgccttttt tataataaca ccatttgtaa taccatatac accagaagga
    30781 acagaatcag tttacatggt aacaggtata ccactaggtt ggatgggttc taagggaatg
    30841 tttgtaggta tgataacagc aataacctct gtaaaattat ttgctgcagt tgtaaaaaaa
    30901 ggatggacat tgaaaatgcc agatggagtt cctccaactg tatcaaaatc atttgcagca
    30961 ttaataccaa gtgcaatagt tatggtagtt ttctttttag ttaagatagc ttttgaagct
    31021 acaccatatg gaagtataca tgaatttata tttaagtttt tacaaatgcc attattaaaa
    31081 ttaggaaata gtttaggtgc tatggcaatc gcttatatat tcttacattt attctggttc
    31141 tttggaataa atggaagtag tgttgttggg gctgtgtata atccaatatt aaaaattcta
    31201 tcagctgaaa acttagctgc ttttcaagct ggttcaaaaa taccaaacat aataacaggt
    31261 caattccaag atatgtttgc gacatttggt ggagcaggta gtacactatc attagtcata
    31321 gctatgttat taatatgtaa aagtaaacgt ataaagtcaa tgggaaaact atcaatttta
    31381 ccaggaatat ttggtataaa tgagccattg atatttggtc taccaataat gcttaaccca
    31441 atactattga taccatttgc aatagttcca acaataaata taataatagc ttacttctgt
    31501 atgtcagcag gattagtgcc tcttacaaat ggagttcagt taccgtggac aactccaatt
    31561 atattctctg gttttttaac aacaggatgg caaggtgcag tcttacaatt agtacttctt
    31621 atactaggaa tatttatgta tataccattt ataaaaatgc tagataagca atacttgaga
    31681 gaagaaaatg aaactgttga agaggaagat gatgatatat cttttgatga tttagtatta
    31741 taggaggaag attatgaaga aaatagttat gatattggac caaatacaag ctggagctgg
    31801 aggaaaagag aaaagtaata tacctcctgc tggaaaatca agcccattag gaccaggtgt
    31861 aatgatggag caatttttaa atgaatctaa ggtaatagct accttatttt gtggggatga
    31921 attttttgta aataatcaag aagaagtaac gagtaagatg atagctatgg taaaaaaatt
    31981 aaaccctgat gtagtaatct gtggaccaag ctttaattac gaaaactttt ctaagatgtc
    32041 agcaatactg tctaaaaata taaatgataa aacagatata ccagcttttg cagctatgtc
    32101 agaagaaaat atagatgtga taaacgaata taaaaatgac atatgtatag ttaagactcc
    32161 caaaaaaggt ggaattggtc ttaatgattc attaaataac atatgtaaat tggcaaaagc
    32221 aatagcaaat aaagaagata taactttgat gaaagaagaa ttttgttatt aataagagta
    32281 ttaattatta gcaagtttaa atattatact atttataata agcatacatt agtaaaatct
    32341 atataattta aggaggggaa ttttaacatg tggggaatga tagcgacatg gagaatggcc
    32401 ctagaaggaa taactgaggc atcagaacat ttagaaaaag gcatggaagc aggtgatgct
    32461 gtagagcttg ctgtaagaag agttgaagac tatccattct ataaatcggt tggatatggt
    32521 ggacttccaa atgaaaattg tgaggtagaa cttgacgctg catttatgga tggtaacaca
    32581 ttagatattg gcgcagttgc tggtataaga gattattcta atcctgtcag catagctagg
    32641 aagttaagtt atgagaaggt aaataatttt ttagttggaa taggtgctga agattatgct
    32701 cgtaaaaatg gatttgaaag aaaaaatatg ttgactgata gagcgaagtt acattataaa
    32761 aagagaaaaa aagagacttt agacaaagga ttaagcccat atgctggtca tgatactgtt
    32821 ggtatgatat ctttagacaa aactggaaaa atgtgtgcag ctacatcaac aagtggattg
    32881 tttatgaaga aaagaggtag aataggagat tctgcactat ctggttcagg attctatgtt
    32941 gatagtagta taggaggagc tacagctact ggtttgggag aagatttaat gaagggatgt
    33001 atatcttatg agatagttag acttatgaaa gaagggaagc atccacaaga agcatgtgat
    33061 attgcagtaa atgaacttga taaacagctt atcaaaagaa gaggaaaagc tggtgattta
    33121 tcattagttg ccatgaataa taaaggtgaa tggggagtag ctacaaatat agctgatttt
    33181 actttttcag tagtaactaa agaagaatct cctactgtat atatttcaaa tagagtagat
    33241 ggaaagacta tacataaggt tatatcaaat gagtggatgg aagcatatga ggctagaata
    33301 aaagcaccaa tagaagtaag tgagtaaagt agtggttaca taattaaaat agagttttat
    33361 aataaggaga tttttatgaa tatcataagt aataaaatag atgagttaaa agaagattta
    33421 ttaagtgata ttatagatat tgtaaaaata cctagtgtca aaggggagtc agaaaatggc
    33481 ttcccttttg gcgaaaaagt aggggaggca cttaataaag cattagaaat atcagaaaaa
    33541 ttgggattta aggttagaaa cttggataat tatattggtt atgcagagca tggagatagt
    33601 gatgattatg tttgtgtaat tggacatgta gatgttgtac atgaaggaga tggttggaag
    33661 catcagcctt ataagggaga agaaactaat ggaagaattt atggacgagg agtactagac
    33721 aataaaggac ctataatgtc tgccttatat ggattatatg ctattaaaga attaaactta
    33781 aaattagata agagagttag aataatattt ggtacaaatg aagaaagtgg atttgaagat
    33841 ataccatatt atttagaaaa agaaaaagca cctattatgg gatttacacc agattgtaag
    33901 tatcctgttg tatatggtga aaaaggcatg gcaaagatta gaataaaaag taaaatcaat
    33961 tatgaagaag atgtatacct aggttttata gaaaatatgt ctgaaaatgt gcttgttaca
    34021 tataaagagc tgaatataga aaatagtgat actatattag atataaaggt aaaatacgat
    34081 tttagttata aattgaaaga tgtattggat gaaataaaag ctagttttcc aaatagtatc
    34141 gatatagagg taatttctaa ttttaatcct gtatattttg ataaagagag taatcttgtt
    34201 aaaaagcttc agctagctta tgaaagggtt acatcattag atggaactcc cgtaacaact
    34261 aatggaggta cgtatgcaaa agtaatgcca aatatagttc cgtttggacc ttcatttcca
    34321 ggacaaaaag gaatagctca taatcctgat gaatacatgg gtatagaaga tataatatta
    34381 aatgcaaaga tatttgcaaa tgcaatatat gaattagcaa aggagtagtt atgttagaaa
    34441 taataggaat gtcagtagaa gacgctaaaa ttatagaaga ttgtggtgca gatagaatag
    34501 agttagttag tgctttaact gaaggtggat tgacaccaag ttttggtctt atagaaagtg
    34561 ttgttaacag tgtaaagata cctgtgaacg taatgataag acatcatgcg aaaagttttg
    34621 tatacagtaa agaagatata agtataatgc aaaaagatat aagtgtggtt aaagagattg
    34681 gtgctaatgg agttgtattt ggtgtattgg ataaaaacaa taatatagat gagaaaaatc
    34741 taaatgtttt attgaaatgt tgtgataatc ttgatgttac atttcataga gcaatagatg
    34801 aatcaaatac aatagatagt gttaaaattt tgaaggatta tgataaaatt acgaatatat
    34861 taacatcagg agggaaagga agtatagttg ataacataca aatgataaag aatatgatgc
    34921 ttagttctaa tcacataaaa attcttttag gtggaggtct taattttaat aatatagaaa
    34981 agataaagga gttaactaag gcaagtaatt ttcattttgg tacagcgatt agaataaata
    35041 acagtccttt tgaagatata gatagacaaa agcttaaaca actcgtaaat ataatttcaa
    35101 gatagtatat gaatataaaa tacttagttt aaataaagag agtaagttaa ttataatttg
    35161 ggtatatgaa tgttaatagg tattaaatat gaaattattg ttgagtatgc tttataactt
    35221 ttaagtagta ttaaatataa ataatgaaag aaaagataga ttatggaggt tttagagggt
    35281 ttatatttat taaaaaatta taaaggtata ttggcatata atacacataa tttcctaaaa
    35341 ttaccatctt atgacatgaa ttcacatatt aataaacaat taatggagat ttttgtggat
    35401 agaaatagga gtaaaaatag ctttaaataa acaaaaacaa gagttattaa cagttttatc
    35461 cacattatcc acaggtgttt gtaataatat taatccacat aagtatcaat gtaactaaaa
    35521 atgataaata attctatcaa ttgaatagaa aaaatcataa aagtaaataa taaaaagagg
    35581 attatgagag ttcgtgtaga atatattatt aaagtataaa ttttcttata ctggcataat
    35641 tgaagggaga tgtatttatg aacataatta tatctggaaa acaaatcgaa ttaactgatg
    35701 caataaaaaa taaaatcgaa actaaactaa gtaagttaga taattacatt catccagaca
    35761 ctgatgtaaa agttacagta agtgcgagaa aagcaagaca aaaaatagaa gtaacaatag
    35821 ctactgtaaa tggtcctata attagagcag aagatatgca ggaaaattta tacacagcta
    35881 tagatgttgt atatgataaa ttaagtaaac aattaaaaaa atataaaaag agattacaag
    35941 ataaacataa agacaacaag agtataagat tccaagatgc agagataaat ctagctgatg
    36001 aacaagagga ttatggggat gaaaatcaag aattagtaat tcaaagacgt aagaaattta
    36061 gtgttaagcc aatgagtgaa gaagaagctg tattacagat ggaattaata ggacatgatt
    36121 tttatatgtt caagaacata gattcagatg aaatagcagt agtttataag cgtaataatg
    36181 gtggatatgg tataatagaa catgaataaa gcaatttaga tttaatcata ttagctatcg
    36241 ataaataaat tatcgatagc tttttaaatt aatattaaaa gtatagtttt tatggtaaaa
    36301 tgaataatag tacaataaag aacgaggaga gatgtaaaat atgagcttta tggataattt
    36361 attcaacatg gcagataaaa aagaattaaa aaagttcaat aaaactgttg atataataga
    36421 ttcattagaa cctaaatttg aatctatggc agactcggaa cttaaaaata tgacaaatat
    36481 atttaaagaa agattagcaa atggtgaaag tatagatgat atacttccag aagcttttgc
    36541 agtagttaga gaagtttcta agagagtgtt aggacttaga cactacagag ttcaaatgat
    36601 tggaggtata gtactacatc aaggaagaat agcagaaatg aaaacaggtg aaggtaaaac
    36661 tttggttgca actgctcctg tttatttgaa tgcgcttact ggaaaaggtg tacatgttgt
    36721 aacagtaaat gattaccttg caaaacgtga tagagaccaa atggcaaaaa tctatgagtt
    36781 tttaggaatg agtgtaggcg ttattataca tggtcaaaat ccaaaagtta gaaaagaaca
    36841 atatgattgt gatataactt atggtacaaa taatgaatat ggatttgact atctaaagga
    36901 caatatggta atacacaaag agcaaagagt tcaaagagga ttaaattatg ctatagtgga
    36961 tgaggttgac tctatactaa tagatgaggc tagaacacca cttatcatat ctggacctgg
    37021 agacaaatca actcacttat attcagatgc aaacacattt gttttaacct taaaaccaga
    37081 tgattatgaa ttagaagaaa aagataaggc tgtatctcta acagcatcgg gtatacaaaa
    37141 agcagaagtg tattttaatg ttgataatat aacagatata tctcatacag aattatacca
    37201 tcatataaat caagctttaa gagcacatgt aataatgaag aaagatgttg attatgttgc
    37261 taaagatgga gaaatagtaa tagtagatga gttcacaggt agacttatgt ttggtagaag
    37321 atattcagaa ggtttacatc aagcaataga ggctaaagag ggtcttaaaa tacaaagaga
    37381 atctaaaaca ctagctactg taacattcca aaactacttt agaatgtaca aaaaactttc
    37441 tggtatgact ggtacagcaa aaacagaaga agaagagttt aaagcaatct acaaaatgga
    37501 tgttttccaa gtacctacta ataagcttat gataagggaa gacttaccag attgtgtata
    37561 caaaagtgaa ataggtaaat ttaatgctgt agcacaagaa ataattgaaa ggcacaaagt
    37621 caatcaacca atacttgtag gtacagtatc aatagaaaaa tcagaattat tatcacaaat
    37681 actaaagaaa aagggcataa agcacgaggt attaaatgct aagcatcatg ataaagaggc
    37741 agaaataata gcacaagctg gtagacttgg agctgttaca atagctacta atatggctgg
    37801 tcgtggtaca gatatagttc taggtggaaa tccagacttt ttaactaaga gagaaatgag
    37861 aagaaatgga tttaaagaag aaatagtaaa tagagtagat actccaatag aaggtatacc
    37921 tgtaaaaggt aatgaaattc tatttgaagc tagagaagag tatgaaaaac tatttgaaaa
    37981 gtttaagcaa caaacacaag aagaacaaaa acaagttgta gaagcaggtg gacttgctat
    38041 aataggtaca gaaagacacg aatctcgaag aatagataac cagttgagag gtcgtgctgg
    38101 acgtcaaggt gacccaggga gttcaagatt ctatataggt cttgatgatg accttatgag
    38161 attgtttggt agtgatagaa tatctggtat tgtagataaa ataggtcttg aagaagatat
    38221 gccgatagaa catagaatat tatctaagtc tattgaagga gcacaaaaga aagtcgaagg
    38281 taaaaacttt ggaataagaa agcatgtact tcaatatgat gatgttatga ataaacaaag
    38341 agaaataata tatgcagaga gaaaacgtgt attagaaggt gaagatttac aagaacaaat
    38401 acaatcaatg actcattcta taatagaaga agcagttact ctttatacac aagataaagg
    38461 atttgatgaa gaaggattca aagaacatat gtataatctg ttcttgccaa aaggtagcat
    38521 agaaatacca gaaatagaaa aacttaatcc agttgaaata acagaaaaag tttatgaaat
    38581 agctatgaag atatatactt caaaagaaga acaagttggc tatgagagaa tgagagaagt
    38641 tgagagagta atcttacttc aagctgttga taaccattgg atagaccata tagatgctat
    38701 ggaccaatta cgccaaggta ttggtcttcg tgctgtaggt cagcaagacc cagttattgc
    38761 ttataaaatg gaaggttttg atatgtttga tgaaatgaat aaacatatca aagaagatac
    38821 tgtaagatat ttatttaata taacaataga aactccagtg gaaagaaaag cagttgtaga
    38881 tgttgaaaat ctatcttctc catcagatgg aacacttcca acaagtaaaa ctgttaaaaa
    38941 agatgaaaag gttggaagaa atgacttatg cccttgtgga agtggtaaaa aatataaaaa
    39001 ctgttgtgga agataatctc ggaggattaa atgttaaagt tacaagagta tagacatagt
    39061 atggagcaga tggcttcaaa tttagaagaa ttgagggttt ctctttgaca tagcttcatt
    39121 gatgaaaaat atacaaatta atgaagaaaa gatgaatcaa caagactttt ggaatgataa
    39181 tgaagtcgct caaagagtac ttcaagaaaa taaatcttta aaagagacat tagaagaata
    39241 tgaaagctta aaaagcttat tagaagatat agaagtatta attgaaatag gtttagaaga
    39301 agatgatgat tctgtagaaa gagatataga aaagtccata gaatcaatgg aagaaaaatt
    39361 atctgaaatg aaaataaaga ctcttctaaa tggagagtat gataaaaata atgctatatt
    39421 atctataaat gctggtactg gtggcttaga tgctcaagat tgggctcaaa tgcttttgag
    39481 aatgtatata agatggtcag aaagtaaggg ttataaagtt aagcttttag atataatatc
    39541 agaccctgaa gcagggataa agacagctac aattcttgta gaaggaacaa atgcttatgg
    39601 gtatttaaag agtgaaaaag gagttcatag attagtgaga atatctccat ttgacccatc
    39661 aggaaaaaga catacttcat ttgcatctat agatgtaaca ccagagttag atgaaaatat
    39721 agaagtagaa attaatccat cagatttaaa gatagacaca tatagagctt ctggagctgg
    39781 agggcaacat gtaaatacga ctgattcagc agttagaata acacatatcc ctactggtgt
    39841 agtagttcag tgccaaaatg aaaggtctca gcatctaaat aaggacagag ctatgagact
    39901 tttaatggca aaattgatag aattaaaaga gttagaacaa aaggaaaaaa tagaagatat
    39961 acaaggcaaa tactcacaaa taacttgggg tagtcaaatt aggtcatatg tttttcaacc
    40021 atataaattg gttaaagacc atagaacaaa tgctgagttt ggaaatgtag atagtgtaat
    40081 gaatggaaat atagacttgt ttattaatga atacttaaaa atgaataaaa tagtttaata
    40141 aatatgcact gtaattaaga tatatgtata agaaggttag tgcttaatat gcacttacag
    40201 cacttaggct gaggacgata accctcagcc ttcgttctgt tttgttatac ttatgaaaaa
    40261 ctaacattag gagtgaataa attggatata aatcaaatct taaaaaaaga gtttaatctt
    40321 agagatgaac aaataaataa tacattaaaa cttattgatg aaggaaatac aataccattt
    40381 atagctagat atagaaaaga aatgactggc gaaatgagtg atgttacact aagagaattt
    40441 tatgaaaaat taatgtattt gagaaatctt caaagtagaa aagatgatgt agttagacta
    40501 atagatgaac aagggaaatt aacagatgaa ataacacaaa atatagaaaa agcaaaaaca
    40561 ttacaagaag tagaagatat atatgctcca tttaaacaaa agaaaagaac tagagcaaca
    40621 atagcaaaag aaaaaggatt agaaaattta gcattgtcaa tactagagaa taatttagat
    40681 aatatagaaa tagaggcaaa gaattatctt gatgaagaga aagaagttct ttctattgaa
    40741 gatgctctaa aaggtgctag agatataatt gcagaactag tctcagatga tgctaagatt
    40801 agaaagtata taagagaatt agctttaaga gaaggtatga tagttagcaa aagtgctact
    40861 gatgagaaat cggtttatga tatgtattat gattatagcg aagcagtaaa aagtatggct
    40921 ccacatagag ttttggcaat aaacagagga gaaaaagaaa gcttcctaaa ggttaagttg
    40981 gaaataaata atgataaagt tttaaattac ataataaacg aatatgtaaa tgataaaaat
    41041 ttcaaaaata aagaagaaat cgtaagttca atagaagatt cttataaaag attaattttc
    41101 ccatcaatag aaagagaaat aagaaatcat ttaacagaaa tagctcaaga aagagctata
    41161 agtgtatttg gaaagaatgt taaaagttta ttgcttcaac caccagttaa agacaaagta
    41221 gttatgggat ttgaccctgc atttagaact ggatgtaaaa tagctgtagt agataaaaat
    41281 ggtaaactac tagattatac aacagtatat ccaacagacc ctcaaaatga tgtagaggga
    41341 gcaaagaaag ttttaaaagg attgattgaa aaatacgata tagatataat ttcaattgga
    41401 aatggtactg catctagaga atcagaaact tttgtatcag aaatgataaa agaaatagat
    41461 agcgaagtgc agtatgtgat agttagtgaa gcaggagcat ctgtttattc agcatctgaa
    41521 cttgcaaatg aggaacatcc agatataaat gtatcaataa gaggagctat atctatagct
    41581 agaagattac aagacccatt agcagagctt gtaaaaatag accctaaaag tattggtgtt
    41641 ggtcaatatc agcatgattt aaacaaaaag agattagaag aagtactaga tggagttgtt
    41701 gaagattctg taaatagtgt tggagtagat ttaaatactg catcatactc cctactagaa
    41761 catgttgcag gaataagtaa agctatagca aaaaatataa tagcatatag agaagaaaat
    41821 ggagatttta cgtcaagagc acaattgaaa aaagtaaaaa gactaggacc tcaagcattt
    41881 actcaatgtg ctggatttat gagaatctta gagggtaaaa atccactaga taatacaggt
    41941 gtgcatcctg aaagttatga tatatgtaaa aaaatgattg agataattgg atattcttta
    42001 gatgatgtaa agaataagaa tataggtgaa atagatgaaa aaataaaaga aattggcttg
    42061 agggaattaa gtgaaaaact ggaagtagga caagttacgt taaaagatat catagctgaa
    42121 atcaaaaaac caggaagaga cccaagagaa gaaggtataa aacctatact tagaactgat
    42181 gtcttaaaaa ttgaagatat acaagagggt atgactttaa aaggtacaat aagaaatgtt
    42241 gtagactttg gtgcatttgt agatattgga ataaaaaatg acggattagt tcataaatca
    42301 gaaatgagta atagttttgt gaaagaccct atgagtattg ttacagtagg tgatatagta
    42361 gatgtaaaag tcattggaat tgacttaaac aaaaaaagag ttgccttatc aatgaaaaaa
    42421 tagataagtt tatgtatggt tatagtactt agattctata tttgtaaatg agattactcg
    42481 agtgcataaa tgttaaaaat ttgtaaaagt atatagtaag aaaatatatt aaaataagaa
    42541 cgatagtctt gaaaatcagg aggaaaatga atgattttta taaaaaatgg taaaataaat
    42601 accataacaa atgggataat tcatggagat atacttatag atgaaggaaa aataatagaa
    42661 attggagaag atttgatagc tcctttagat gtagaggtaa tagatgctag taataaactt
    42721 gtgtttcctg gatttataga tgctcatact cacttaggtt tatgggaaga tggtataggg
    42781 tttgaaggag cagatggaaa tgaagagact gacccaataa caccacaatt aaatcctata
    42841 gatggaatta atccaatgga tagaactttt aaagaagctt ttgaaggtgg aataacttct
    42901 gtttgtacaa cccctggaag tgcaaatgtt atgggtggtc aatgtatagc tataaagaca
    42961 tgtggaaaaa gaattgataa aatggtaata aaaaatccag ttgcatctaa aattgctttt
    43021 ggagaaaatc caaagagctg ttatggtcag gatgataaat ctcctcaaac tagaatggct
    43081 atagctgctt tacttagaga aaacctaaaa aaagcagaag aatatttaga ggatattgat
    43141 atgtatgaga gtcatgatga tgaagactgt gaaaaacctg aatatgatat aaaaatggaa
    43201 agtttaatac cagttttaag aagagaaatt ccttttaagg cacatgctca tagagcagat
    43261 gatatgttta cagcaataag aattgcaaaa gaatttaatt taaagcttac attagaccat
    43321 tgtacagaag gtcatcttat tgtagatgaa ttagtggaag aagggtttcc tgtaatagta
    43381 gggccatctt tgtcagaaag gtctaaattt gagcttagaa atttgacatt taatacagca
    43441 ggaatacttt caaatgcagg tcttgatgta tgtataatga cagaccatcc agtaatacca
    43501 gttcaatatc ttccaatatg tgcaggtatt gcagtaaaac atggtatgaa agaagaaaaa
    43561 gcaatagaat caattacaat aaatccagct aagactttag gaatagaaga tagagtaggc
    43621 tctatagaag ttggtaaaga tgcagaccta gtaatttggg ataattctcc actagagatt
    43681 caaagtaatg tactttacac tataataaat ggcaaagtag tgtatgagaa aaaataactt
    43741 gacaattatt aaaaaattaa ctaatataag agtgtaagga aaattaaaaa atcaaagaag
    43801 atcttcgggg cagggtgaaa ttccctaccg gcggtatagc ccgcgaacta cttaggtggt
    43861 tgatttggtg agattccaaa gccgacagta aagtctggat gagagaagat atttatggaa
    43921 gataaataag tttattttag tttgtttaaa ctatatccat aaaaactcga agatagggtc
    43981 ttcgagtttt ttgtttttcc taaaaaatat aaacatattg attaggggga aaataattat
    44041 gcaaaacaca gcaaaaagag gcaatatgat ttcaacaaga actttagtag taatgtcaat
    44101 tttatctgca atatcttatt tattaatgtt tattcaagca ccaataccag gtatatttcc
    44161 agatttctta aaaattgatt tatcagatat tccagcaata ttcggaggaa tgtctctagg
    44221 accattagtt ggatttggaa tagttgtagt aaaaaatgtg ttacaagcaa taacagcaac
    44281 aacaactgga ggaataggag aatttgcaaa tatattaatt ggtggttctt atgtaatgat
    44341 actttgttat tcatataaga gaagtggaga tttaaaaggt gtactgattg gttttgtatt
    44401 aggaacaata tctatgacta taattggttc attagtaaat tattttgtaa tgttgccact
    44461 ttatggtcaa cttatgggac tagatgctat aataggttta ggttcagcta taaatcctca
    44521 agttcatgat ttattcactt ttgtaatttg gatgatagct ccatttaatg tgctgaaggc
    44581 tgttataata tctttagtaa cattgccact ttataaaaaa atgggaaata taataaagaa
    44641 ataattagac aagaaaatat aaaattaaat gtattgaata gccataattt atttataact
    44701 tcagtcctat attgtgattg atatattaaa tatattatgg ctttattaat ttatcaaaaa
    44761 atgtatataa aataagaaat atttagacaa atttaaattt taaaataaag gaagaattaa
    44821 aacgattaac tattaaaata tgaaaaaggt atctacaata tacagagcga atttataata
    44881 aacaaaaaat aaagttatta ttaaaaaact ataaagatta ataatcaaac ttttaataat
    44941 aactaattta ataatgatag gggtgtatat tcatgcattt atctaaaaaa ataaaaaaat
    45001 tatttttaga tgataaaggg tattatttta atagtaattg gaaagatatt catattggta
    45061 tttatgatac aaaattagga gattctttaa agtatatcac taatgaatat attgaaaata
    45121 tggaaagggt aaaatacgat tatcgtgaat taaaaaatat agaaaatcaa actgatggta
    45181 tgtgtatttt agcaataagg cagaattaca aggcattaga gtatgtaaaa aatcaaaccg
    45241 aagaattatg tttagaagca ataaagtata attataaagc acttgaatat gtaaaagaac
    45301 aaacagaata cttgtgtctt gaagctataa aaaaagattg taatgcactt aagtatgtac
    45361 gaaataaaac agaagggctt attataaaag caataagtca ttcttccaat atagatgttg
    45421 taagtatact aaaggcttta gagactcaaa caagaaggat atgtttagaa gcaattaaaa
    45481 aagatggcag gtgtcttgca tacgttagag aacagagtga agaattatgt atagaggcca
    45541 ttaagcaaaa ttataaagca ttaaaatatg taaaaaatca aacggaaaaa atgtgtatag
    45601 aatccgtaag acaaaatggt atggcattac aatatgtaaa taaacaaact gataaaatat
    45661 gtatagaagc tgtcaaacaa gatggaagaa gtctacaatt tgtcaataat aagacagaag
    45721 aaatatgtat aaatgctata agatatttaa ataaaaaata taatattaaa gatgtactaa
    45781 gttacataga taagtataca gaaaatatat gtatagagat tgtaagacaa aatggaaaaa
    45841 tgcttatgta tataaaaaat caaacagaaa aaatgtgtat tgaagcagta aaagagaact
    45901 ataagtctct taagtatgta aaagagcaat ctgagagaat atgtaaagaa gcattgaagc
    45961 aaaaccataa agcaaaagag tatgtaaaaa ttgctattga tgattgtata taaggtgtag
    46021 atacagccat caatagtgaa agataaaaaa agataaagac aagtacttta taataatcta
    46081 ggcttatact ataattaatt aagcagtgat ataaattcac atgacgatta tatcaaaatg
    46141 gagatgaatt gatggcaaaa atatatttag aaaatgaaaa taaaactaga gaaataggat
    46201 ataaattagg taaactttta aaagaaggca gtgttatctg tttagtagga gatttaggag
    46261 ctggtaaaac tacaatgaca caaagcttgg cagattcatt agggatagaa gattatataa
    46321 caagtcctac ttttactata ataaatgaat atgaaggaaa aatacctttg tatcattttg
    46381 atgtttatag aataggtagt agtgatgaaa tgtatgatat tggttatgat gaatatgtaa
    46441 attcaaatgg aatctgtata atagaatggg ctaatctaat agaagatata cttccaaaag
    46501 aatatttgaa tatagaattg agatataaag atgaaggaag agaaatgata ttaactccaa
    46561 aaggagagtt ttataaagag atagttgagg agttgattaa ataatgaaaa tactaggtat
    46621 ggatacgtct tctatggcag caagtgtagc agttgttgaa gatgataact taatatgtga
    46681 gtttacagta aacaacaaaa aaactcattc acaaaagctt atgccaatga tagaaaatat
    46741 gttgagtatg agtgatttaa gtataaaaga tatggattta ttagctgtat gtataggtcc
    46801 aggttcgttt acaggactta gaataggtat ggctacagta aaagctatgg cccatgtaaa
    46861 taatatacca ataatagcag taaattcttt ggaatctcta gcaaataaca taaatttctg
    46921 tgatagaaag atatgttgta tattagatgc tcagaaaaat caagtttatt cagctaaata
    46981 caagtttgaa aatggagaga tgatagaatt agatggtgtt gatgttgtag agtttgatgc
    47041 tttagtagat gaaattgtat caactaatga agaatttata atagttggag aagctgtata
    47101 caaatataaa gacaagttag agaatataaa aaatataaaa ataccttcac cagctaataa
    47161 tgtatctaac gcaggaagct tatgctcttt agcgttaaat aaatataata aaaatataga
    47221 tgtacatact tgttatacga taaatcctat gtatatcaga aaatctcaag ctgaagtaca
    47281 atatgatgaa aaaatgaaga ggctaaataa tggaagataa tacaaaacta atagtagatg
    47341 atataaaaat agaagaaatg actacagaag atatagatga agtttttgaa gtagaaaaaa
    47401 attgttttga agattattgg tcaaaagagt cttttagaaa agagttgtct aatgaagtag
    47461 caaggtatat agtagctaag ttaaatggaa aaattgtcgg atatgtggga atttggctta
    47521 tacttgatga agggcatata aataatgtgg ctgttcatag tgactataga gggaaaaaaa
    47581 taggggacaa gttgataaaa ggcatagttg atttatgtaa agataataat attgcatcta
    47641 tgacattaga agttagagca tcaaataaaa tagcacaaaa tttatataga aaatatggat
    47701 ttaaaatggg tggaataaga aaagaatact acagtgataa taaagaagat gcaattataa
    47761 tgtggaacca attaaaagag gtgtagagtt tatgagtgat ataataacat tagctataga
    47821 gagtagttgt gacgaaacag ctgcatcagt tttaaaaaat ggtagagaag tactttcaaa
    47881 cataatctct actcaaatcg agacacataa aaaatttggt ggtgtagttc cagaagtggc
    47941 ctcaagaaaa catgtggaaa atattgatat agttgttcaa gaagctttag acaaagcaaa
    48001 tataggtttt aatgatatag accatatcgc agttacatat ggacctgggc tagtaggtgc
    48061 tttattggtt ggtctatctt atgctaaagc acttgcatat actttgaata ttccacttgt
    48121 aggagtaaat catatagaag ggcatctaag tgcaaactat atagagcata aggatttaaa
    48181 acctcctttt ataacattaa tagtatctgg aggtcatact cacttggttg aagtaaaaga
    48241 ttatggcaag tatgaaattt taggaaaaac aagagatgat gcatctggag aagcatttga
    48301 taagatttca agagctatga atttaggcta tccaggaggt cctattattg ataatctggc
    48361 caagaatgga aataaacatg ctatagaatt tccaagagcc tatttagaag aagatagcta
    48421 tgattttagt tttagtggat taaaatcttc tgtattaaat tatctaaatg gaaaaagaat
    48481 gaaaaatgaa gaaatagtag ttgaagatgt agcagcatct ttccaagagg ctgtagtaga
    48541 ggttttatct actaaagcac taaaagcagt aaaagacaaa ggatacaata tcataactct
    48601 ttctggtggg gttgcttcta attcggggct tagagctaaa ataacagagc ttgctaaaga
    48661 caatggtatt actgttaagt atcctcctct aattttatgc acagataatg cagctatgat
    48721 agggtgtgca ggatattata attttataaa tgggaaaacg catgatatga gtttaaatgc
    48781 agttccaaat ttaaagataa atcagtagag ttagatgaat ttgtaaatat aaaagtattg
    48841 tttcaaaaaa gtaagtagaa gtgaaattaa atataataaa aataaatata gtatatatta
    48901 aaacttgaag taaaactatt tataatcttt atattccaat gaattgcaac aaattttagg
    48961 atatacagat tgtctttggc ttagatttgc ttcaagttta tttttttcta tagaaagatt
    49021 attttaaaaa gtgggtaata tacccttttt tttcattctt aaaaagtttt atactaatta
    49081 tagaaagatt aaggagggga agaaatgagt caaagtaaag aagacaaaat aagaagtatt
    49141 ttggaagcaa aaaatattaa atcaaatttt caaaataaag aaaatttaag tgaatttaat
    49201 gaaaaaaaag caagtaaaag agcagaagac ttattagatg tatattataa tacattatct
    49261 actgctgata tggaatttcc atattggtat aatagagaat atagaaaatc agatggtgat
    49321 ataccagtag ttagaagagc taaagctctt aaagctgctt tttcacatat gacaccaaat
    49381 ataatacctg gtgagaaaat agtaatgcaa aagacacgcc attatagagg ttcttttcca
    49441 atgccatggg taagtgaaag cttctttgtt gctcaaggag aacaaatgag agaagaggca
    49501 aagaaattag ccagtaatac agctgatgaa cttacaaaat ttgggtctgg tggaggaaat
    49561 gttactgaaa gttttggaaa tgtcgtttca atagctggta aattcggaat gagaaaagaa
    49621 gaagtacctg tacttgtaaa aatggcaaag gaatgggttg gaaagtctgt tgaagattta
    49681 ggttttcact atgaaaaaat gatgccagat tatgatttaa aagaaaacct aatgagtaca
    49741 cttatatgca tgtttgattc agggtataca cttcctcaag gtagagaagt tataaattat
    49801 ttttatcctt taaattatgg attagatgga attatagaaa tggcaaaaga atgtaaaaag
    49861 gcagttgcag gaaatgcatc tggagatggg cttattggta tggaccgtct atatttttat
    49921 gaggctgtta ttcaagttat tgaaggatta caaacttgga ttttaaatta tgcaaaacat
    49981 gcaaaatatt tagaaagtat agagacagat ttagaagcta aaaaagaata ctcagattta
    50041 gtggagatat tagaacatat tgcacataaa caacctcgta catttaggga agctcttcag
    50101 ttgacttata caattcatat agcgtcagta aatgaggatg ctatatctgg tatgtctata
    50161 ggacgttttg gtcaaatttt atatccttgg tatgaacaag atatagaaaa aggactaatt
    50221 acaaaagaag aggttatcga attattagag ctttatagaa taaaaatcac ttgtattgac
    50281 tgttttgctt cagcgggcgt aaatggagga gtactatcag gcaatacatt taatacttta
    50341 tctataggtg gattaaaaga agatggttct acaggagcta atgaactaga agagttatta
    50401 ttagaagcaa gtatgagatg tagaactcct caacctagtt taactatgct atatgatgaa
    50461 aagcttccag aagatttctt aatgaaagct gctgaatgta caaagcttgg ttctggttat
    50521 ccagcatggg taaacaactc aaatggaaca acatttatga tgaaacaatt tgctgatgaa
    50581 ggtatgactg ttgaagaagc aagagcattt gcattaggtg gatgtttgga aacgtctcca
    50641 gggtgttgga aacagttaac tttaaacgga aaaacgtact ctattgcagg tggagcaggt
    50701 caatctgctg gctctggagt tcactttata gctaatccaa aaattttaga acttgttctt
    50761 atgaatggta aagactatcg tatgaatata caagtatttg agcctcataa taagccatta
    50821 gatacttatg aagaagtcat agaagtattt aaagattatt ataaacaagc aataaatgtt
    50881 ttagaaagag caaataacat tgagttagat atatggagaa aatttgatac ttctataata
    50941 aattcactac taaagccaga ctgtttagac aaaggtcaac atataggaaa tatgggatat
    51001 cgttataatg caacattaaa cgtagaaact tgtggtactg ttactatggt caattcattt
    51061 gcagctctta agaaacttgt atatgatgac aaagcattta caatagagga aatgaaggat
    51121 gccatattaa ataattttgg atttaaagat gcattagaag taggaaatta ttctatggca
    51181 gaccaagtaa aagtagataa gactggtaaa tatgatgcta tttataaggc ctgtcttgat
    51241 gcacctaaat atggaaataa tgatttgtat gcagataata ttcttaaaaa ctatgaggta
    51301 tggttatcaa aagtatgtga agaagcacaa tctttatatg ctaagaagat gtacccttgc
    51361 caaatatctg tttctacaca tgggccacag ggagctgcta ccttggctac tccagatggt
    51421 agactaagtg gaacaacata ttcagatggt tcagtctctg catatgcagg aacagataaa
    51481 aatggagtat atgcattatt tgaatctgca actatttggg accaagcagt agttcaaaat
    51541 tctcagatga atttaaaact tcatccaact actataaaag gacaacaagg aactaaaaaa
    51601 ttattagatt taacaagaag ttatttaaga aaaggtgggt tccatattca atataatgtt
    51661 gtagattcag aaacattaaa agatgcacaa aaaaatcctg acaattatcg tcaattaatg
    51721 gtacgtgttg ctgggtttac tcaatattgg tgtgaattag gtaaaccaat acaagatgaa
    51781 gtaattgcta gaacagagta tgaaggggtg taaaatatga gaaagcatag tgattgtatg
    51841 aatttttgtg cagtagatgc aaccaaagga atttgtagat tatcaaaaca aatgattaat
    51901 ttagatgatg cagcatgtcc agagataaaa gtaatgccaa aatgtaaaaa ttgtaaaaat
    51961 tttgttgaag ctaatgatga aggtataggc aaatgtgttg gcctagagaa agaagactgg
    52021 gtatattcaa cattgaatgc aattacttgt gaaggacatg tgtttaatga gtagtcaaaa
    52081 gcaattagaa ggcatgattt ttgatgtaca aagcttttca gttcatgatg gtccaggttg
    52141 tagaacaact gtatttttaa atggatgtcc actgagttgt aaatggtgtg caaatccaga
    52201 aagttggact gtaagaccac atatgatgtt tagtgaatta tcttgtcaat atgaaaatgg
    52261 atgtactgta tgtcatggta agtgtaaaaa tggtgcattg agctttaatc ttgataataa
    52321 gccagttata gattggaaca tctgtaagga ctgtgaaagt tttgaatgcg tcaactcatg
    52381 ttattataat gcgtttaaat tatgtgcaaa accttacact gtagatgaac ttgtgcaggt
    52441 aattaaacgt gattctaaca attggagaag taatggagga gtaacattta gtggaggtga
    52501 gccactactt cagcatgaat ttttacatga agtattatta aagtgtcatg aggtaaatat
    52561 acacactgcc attgaaacga gtgcatgtgt atcaaatgaa gtttttaata aaatatttaa
    52621 cgatattgat tttgcattta ttgatataaa gcatatggat agagaaaaac acaaagaaca
    52681 aacaggtgtg tataatgatt taatattaga aaatatatca aaccttgcaa attctgattg
    52741 gaatggaaga ttagtactta gagtaccagt tatctctggg tttaatgata gtgatgaaaa
    52801 tataagtgat attatatctt ttatgcacaa aaataatttg gtagaaatta atctattacc
    52861 atttcacaga ttaggagaat caaaatggac tcaattaggc aaggaatatg agtattctga
    52921 taagggtgat gttgatgaag gtcatcttga agaattacaa gatatatttt tggataatgg
    52981 tatagcttgt tatgttggtc atgagacagc tttctaaaat taaatacaag ttttaattaa
    53041 aaaaggatgt tacactaaaa gctagagtta catccttttt tatgtggttt ttatgtagaa
    53101 ataattaagt aaagttttat atgttttata tattgtttat attgctttat gtccataaat
    53161 attgctttaa atatacttta tatatttttt atagtttaaa ttacagttag agaatatatt
    53221 acgtttactt cattgaagca gaagttttgt ggtaaaatac tactatgaaa aaatttaata
    53281 gaatatattt tagaaacaac taaaaataat agttaggagg aagacatcta tatgaacaaa
    53341 tcatggagca acttgattat taagaataaa gacagaaaag tacgttcagg gtggattatt
    53401 atagctgtta tggctacctt ttacatactt cagtattatt taagcatgat acttgtggaa
    53461 ataataagaa aaatcttggt tgctacaggt gacattaatt taaaaacaaa ctatttttca
    53521 gaatatgcta attggttaaa tgatgttggg ttacagattg tatttcaaat tctaacagat
    53581 tcacttatga ttattattcc tataattgta tggagattta ttatgaaaaa tcctattagt
    53641 gaaatgggat tacattctta tagaattaag aaaaaagaag gatatgtagg aatgttatta
    53701 ggaatattta attgtacagt aatctttatt ataacaataa caattggtgg tggtcatgtt
    53761 acttcatggg taccaaaaat ttcacctttg acagtttctt ggatacttgt ctttatttta
    53821 gttgcttttg cagaagaaat tttaaatcgt ggttttttta tggcagtttt acgaagatgt
    53881 aaaaatattt attttataat gattgttcca tctgttattt ttgggttgat tcatatatgg
    53941 aatcctgatg ttactttttt gtctgtaatt aatattataa ttattgggat tcttttttca
    54001 tatatgttta taaagtcgtc gaatatatgg atgtgtatag gttatcattt tacatggaat
    54061 gtatttcagg ggattatata tggtatgcct gtaagtggac ttcaggttcc agggattata
    54121 actacacaaa tcactcatgg taatctatta aatggaggga tgtttggtat tgaaggtgga
    54181 attttgacta cttttgttaa tctacttagc tttatatttg tatggtatta ctatagagat
    54241 tctaagtatg attttgttag tgataaagta aatgtgacca atatcaagaa ttagttgatt
    54301 ataataaatt ttaataatat cttctaagct taaagtattc tgtaggattg ttggaaattt
    54361 gcaaaaatat aaaaataact tggatattct atttactcca agttattttt atattctttt
    54421 gtaaatagaa atggaacata aaaaattaaa acaaccatag atactattag tatatcatgg
    54481 taagtgatag ttgattcttt agaatttgtg ataagaaaag cactattatt taaaacatga
    54541 attatagcac aaaaccagat attcttagtt tttatataaa gatatcctaa aaatattgaa
    54601 attccaacta tatgtattga acgtaatatt attcctaata ttggcgcttc aggtgtatat
    54661 aatgtaaata ttagtggtaa gtgccacaag ctccaacaca tacctaatat tataactcct
    54721 aactttttac caaatttatc aaaaaaaata ttctgtaaaa aacctctcca ggcatattct
    54781 tcactaaaaa aaatataaat agtagttaat gatgttattg gagtaaatat aaattttatg
    54841 ataccactat aattaggttg agccccttgt agtattagta taaatgatgt tggaacaatt
    54901 acagaaatca taaagtaaat aattaataaa gaacctagtt taatattttt tacaggatat
    54961 aaattttttt tatttgatga atatattata attgataagc tacttataaa agttaatatt
    55021 aggtttataa ttataaattc attattattt attagattta ataacttaag aacaattaat
    55081 aatgaataaa taagaaaaaa taatatgatt agtgaataaa attcatacat atcattattt
    55141 aatccttcag tataaaactt tgcaatagca actgaagata gaggtaatat catcatgaat
    55201 gatgcaaagt tttctggatc aataaattta ttataatata acagtaaacc taatgaataa
    55261 gttaaaccaa agtttataaa gaaaaagata ataatttgta ttttttttct ttttatttca
    55321 tttttaataa atactgggtt tagaatattt atccatatta attttaagtt cattaattta
    55381 atactccttt acaatataga ttcttaacta aattaaaata ttttattgaa tattataaat
    55441 tcatgacagt caatattatt gaaaagtaac ttataaaatt atatataaat aataaaatta
    55501 attttactat ctacctatat atttagttat attgcaggca gaatgtggtt taccataacc
    55561 aaaaggacaa taaaaaatat ttttctatat ttttattatc tttttgtaaa agatttatta
    55621 tttattgcat taaattaata ggcagtagag gcatagttga taaaattaat gaagaaatta
    55681 aacttatgaa tataaattta ttattgagtt ttaatattac atttattatt ctctttgatt
    55741 ttaatatttt atatttaata attattacat tcgtctggtt aataaataat aattaaataa
    55801 atcaaatgat tttaatttac tatatgatta taatataacg ttga
//
LOCUS       DAEORM030000023        54086 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.023, whole genome shotgun sequence.
ACCESSION   DAEORM030000023 DAEORM030000000
VERSION     DAEORM030000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 54086)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 54086)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 54086)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..54086
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.023"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            complement(264..632)
                     /locus_tag="KRH23_001837"
     CDS             complement(264..632)
                     /locus_tag="KRH23_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C-GCAxxG-C-C family (seleno)protein"
                     /protein_id="HHS5225117.1"
                     /translation="MTRPSIYHSQGYTCAEALIKSYNEEHNTDIPISIGSGMGVGMNV
                     GSVCGAVNAAVVIIGYLNGRNSNLDENIARKYSRELLNRVRNKYSSEICVSLKKNKIT
                     CEEIINFTYDALNDMLKNQK"
     gene            1075..2031
                     /locus_tag="KRH23_001838"
     CDS             1075..2031
                     /locus_tag="KRH23_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HHS5225118.1"
                     /translation="MKKILITGALGQIGSELTIKLRNEYGEQNVIASSRRVKEGNPVC
                     ESGIFEILDVTDKNRFFEIAKKYDVDTIIHLASLLSAVAESKPLEAWNLNMNGLINGL
                     EIAKELDCKFFTPSSIAAFGENSPKNMTPQDTLQRPNTMYGVTKVSGELLCDYYHSKF
                     GVDTRGVRFPGLISYVTPPGGGTTDYAVDIYYEALKNKRYKSYIAEGTKMDMMYMPDA
                     LQSIVDLIEAPADKLIHRNAFNITAMSFSPEEIADSIKKYIPDFVIEYDVDPIRQSIA
                     DSWPNSLDSSSAVKEWNFKFSYDLDKMTKDMLEKLSEKGIGK"
     gene            2249..2596
                     /locus_tag="KRH23_001839"
     CDS             2249..2596
                     /locus_tag="KRH23_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5225119.1"
                     /translation="MLNLKEIREEIIKKYIGDSLISELTEELKNILITDLQSNPFKSN
                     IELSIIPANIEIFKKIENILIDSKVNLKMGWERILINYILKDLFELNYEINKSCNEPL
                     MFRVIISIDSYDA"
     gene            2636..3610
                     /locus_tag="KRH23_001840"
     CDS             2636..3610
                     /locus_tag="KRH23_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004527 - exonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease domain-containing protein"
                     /protein_id="HHS5225120.1"
                     /translation="MKYKLFIDFEFNILDDNKNKPKEYNGAELISIGGILVDNEFNTI
                     DNYYSLVKPKYNKILSNKCKNLTKLNQLDINNAPNLLYVMDDFYKWFCKFDDVTIYNW
                     GDFDIAGLLTSFRVYKYTGKCLELFNMMIDIQPFISQHITYNNRILSKQISLLNMKKI
                     FSVKGDIKHNSLSDAVDLMNVCKCFFFNSPKNIDILEELYNKLPALKTPLYYIPYFED
                     ENFELKFDRTPEDIIIYLKQILTILNISKKEIYFKKRSVLVNNSKIINFKNLSSSFKL
                     IKLNEFEEYPDFILKLGDKKSFVESVIKINKSNRKSIKNLILKLSKKP"
     gene            3716..4375
                     /locus_tag="KRH23_001841"
     CDS             3716..4375
                     /locus_tag="KRH23_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HHS5225121.1"
                     /translation="MTVVLIRSIILYITVLIALRVMGKGEIAEMNCFDLVITLLIAEV
                     ASVPMENNNIPIINGVAAISGLVIMQTLISFLSLKSRKLSSFLSGKPSVLIDKGKIVY
                     KELKKERISIDELLEQLRIQGYFNLKDVQYAILETDGNLSVVPASSYNSTPPRAFNHL
                     PIPLILDGRIINKNLDIAQKDTNWLMGILKSNHIETFKDVLICVLDENDKIFIQNKKG
                     D"
     gene            4378..4758
                     /locus_tag="KRH23_001842"
     CDS             4378..4758
                     /locus_tag="KRH23_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4363 family protein"
                     /protein_id="HHS5225122.1"
                     /translation="MKSTTFVILWTILFVLFGFYVNNKLYDFTEGYKDNISVLEKSIE
                     NEDWEKAQKEADSISTSWNKEKNHWYKVLNHEYFDEIGLRFNILDKAIYTENKLKSLE
                     EVESIKTYLGNIIESVKFDVNYIF"
     gene            complement(4847..6010)
                     /locus_tag="KRH23_001843"
     CDS             complement(4847..6010)
                     /locus_tag="KRH23_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HHS5225123.1"
                     /translation="MRTVKQVSDLTGISVRALHYYDEIGLLKPNKITDAGYRLYDDES
                     IKTLQQILFFKEIDIPLREVKEIMSSQYFDKVEALKNQKKLLILKRKRLDELIELINQ
                     TLRGEGNIDFKEFDMSEYFNVLEEFKREHRNKVIKIYGSVEKYNEYIERVKSNEEKIA
                     KMAIKQYGTIEKFAQAIKTNFSSDILNLGEKFDRYKNDCLKEKHPKLKELYRKLVEDL
                     SRNPSSTDLQEIAKAITDISKKDYEIFSMDTGDDNWYYMVQNYLVNPTWIEEVDKKYG
                     SGAGKFIGQVLKTYLRDRKPKINTLYEKLVEDLSRDCSSREVQSIVEEIDNEMKRSNE
                     FYKIDNGERYFDYMSELYLQDSNYIKVTDKNYGDGASKFIGEAFKIYFDNNNC"
     gene            complement(6118..7164)
                     /locus_tag="KRH23_001844"
     CDS             complement(6118..7164)
                     /locus_tag="KRH23_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BtrH N-terminal domain-containing protein"
                     /protein_id="HHS5225124.1"
                     /translation="MRKIIEIKHHSHDYECMWNGIEDLYINKTGECLPNDFFFLLSGF
                     GSFCYMKTNKADLKRMVALGDGRTKQMYKFLAPIVGFEYKHHEFKKYEQALKKAKSEI
                     DDGYPVILGALDMYYLPYYKKLYHKEHIPFHYILMVGYDDEGIYLYDCGRTELLHLSY
                     DKLRESMNCNSPGLSKENTICTIRMNTSKNKYNIAREAIAIKRDMFLNPPKGFLGYKG
                     FEKFIKELPQWNTELDKDDYDKILTNMVMFFGTVPTIPNAIKGIKEPDTVQFKGGFDK
                     MSRMLNSIGEEYKNDSFIQVADIFDKTAIIIDKISNIIIDYLTQTCDDTEQLPLLFSE
                     VLEHMKTGYLILDV"
     gene            complement(7411..8610)
                     /locus_tag="KRH23_001845"
     CDS             complement(7411..8610)
                     /locus_tag="KRH23_001845"
                     /EC_number="6.3.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004055 - argininosuccinate synthase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006526 - L-arginine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase"
                     /protein_id="HHS5225125.1"
                     /translation="MKEKVVLAYSGGLDTSIIIPWLKENYEDIDVIAVCGNVGQEDKM
                     EDVYEKALQSGASKAYVDDISEEFVTETIFKAVKAEAKYEGKYLLGTSLARPIIAKKL
                     VEVAHKEGAKYICHGCTGKGNDQVRFEATIAALDPTIKVIAPWRIWDIKSREDAIDYA
                     EKHNIKVTATKAKIYSVDANLWHVSTEGGDIEHLENEHKKDVYKQCVDPEDACDVAEY
                     VEVYFEKGVPKKVNGEELSPVALIHKLNELGCKHGIGVIDIVENRLVGMKSRGIYETP
                     GGTILYEAHNILESATLDKDTLHFKQMVSYKYGELIYNGLWYCKLRESIDAFMEQTQD
                     NVTGTVKVKLYKGNIKPAGIFTENALYDEGISSFGNSELYDHKDAEGFINLFTLPLKI
                     RAMKAGK"
     misc_binding    complement(8863..9070)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(9181..9918)
                     /gene="truA"
                     /locus_tag="KRH23_001846"
     CDS             complement(9181..9918)
                     /gene="truA"
                     /locus_tag="KRH23_001846"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HHS5225126.1"
                     /translation="MRNIKMIVAYDGSRYKGYQKLGDNNMTIQEKLENVLSKMTNETV
                     EIIGSGRTDMGAHARGQVVNFRTNCMDSLDKIQKYLYEYLPEDIVVKTVEEVDERFHS
                     RYNVKSKTYMYKIDNNKYHNPFIRKYATHVSKKLDLDRMRKASEYLVGEHDFTSFASS
                     KSKKKSNVREIYSINIKEDDNVIEIYVEGNGFLYNMVRIIVGALIDVGLKRRAPQDIK
                     YMLESKDRCQSSDTAPAKGLCLWKVTY"
     gene            complement(9940..11373)
                     /gene="walK"
                     /locus_tag="KRH23_001847"
     CDS             complement(9940..11373)
                     /gene="walK"
                     /locus_tag="KRH23_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     WalK"
                     /protein_id="HHS5225127.1"
                     /translation="MLHFEGLRKKVIKNYFIIIIIMVTLFEGLFMFYIQNYYYDSVKQ
                     LLESEIKYADEYNAITMETTSFEKKVKNIFDKQPLTKNSEFGISIIDKDKNIILDQYG
                     FKSKEKANYEDVNNALKDIKTKNLTPYTYRIPDTGEHVMSISLPLKVNNIIEGVVRYT
                     VSLDAIDNAILKQATWLILAGIFILIIAILISLKFAETLIKPLRELKKFANELAVGNY
                     NIKLEKMKIVDDEIGDLAQTFEHMAHEIDKSEKLKEEFISSVSHELRTPLTSIKGWSE
                     TLGYESITREELDLGLGIIQDETERLIKLVEELLDFSRLSSDRIKLHVDIVDVEGLIV
                     GVVNQLKVKAAEKDISLLFEFENEFIENIQGDKNRLRQVLINLIQNSFKFTSQGGYIK
                     VVASQDEEITTISVEDNGSGIEKQNLNKVLDKFFQEDYNKAGSGLGLAISNEIVKLHG
                     GRMKIESEKNVGTKITFNIKNKFAKQA"
     gene            complement(11376..12074)
                     /gene="walR"
                     /locus_tag="KRH23_001848"
     CDS             complement(11376..12074)
                     /gene="walR"
                     /locus_tag="KRH23_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism DNA-binding response
                     regulator WalR"
                     /protein_id="HHS5225128.1"
                     /translation="MKEKILILEDEIGIRSFVSINLKREGYEIVEAGTGREAIEKMTT
                     EKDITIALLDVMLPDISGIEVCKFIRENFDQVGIIMLTAKAQEDDKIEGFISGADDYI
                     IKPFSIKELLVRVSALLRRVAKDDSSVKSSEIVSPPFILDIDKRKLFKNGKEIELTPT
                     EFSIVKYLISNAKQSLSRDQILDEVWGTNYLYDFKIVDVNIRRIRNKIEDDPSKPKYI
                     QTIWGYGYCFRKEE"
     gene            complement(12103..13491)
                     /locus_tag="KRH23_001849"
     CDS             complement(12103..13491)
                     /locus_tag="KRH23_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5225129.1"
                     /translation="MKVLKLITVVALMMLFVTGCNIKTESPEQLAKIPDYDDTKKVLY
                     DGIDQLLKPDSSMILPSNTKEVGKINKVDLNSDGIDELVVFEQKEDLSNNVSQVGFVT
                     LSYNGEKYVLGDHFLENGESIEYANFYDLDSDGYKEVILLVKSKDKTNMHIYKVVDNE
                     ITKIYDLDASWLQNKEDFNDMKVKIGYIDGDDKLDILMLHLNNKTNEMFASVANFDGK
                     MKIKDSVKFENVKNLSELYITLGNVASSIGNSSAAIKGIVLDIPILKDNNYITQILYM
                     KDGKINKAFSDYDKTITKSYYIPVDDIDKDKIIEIPIVAGSTGNNKNTYSSKSSATIS
                     WYRWNGKEGADSSLIFTSQIYYNYKYNFKLFIPNNLFDKILVEQEFVGEKAVFKFYYF
                     DYSDRKNLFNIVVESKNKLEDRKNTGTQNSIVLQESDEYTFLLVVNNANEMDKLDMTI
                     DALKEYFSLIYG"
     gene            complement(13635..14783)
                     /locus_tag="KRH23_001850"
     CDS             complement(13635..14783)
                     /locus_tag="KRH23_001850"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0001510 - RNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="THUMP domain-containing class I SAM-dependent
                     RNA methyltransferase"
                     /protein_id="HHS5225130.1"
                     /translation="MKNYTLISPCFFGMEKMLAREITNLGYEIIKTEDGRITYKTDEF
                     GIAKSNMWLRCAERVHLKIAEFEAKSFDELFENTKRINWSRYIPYGAQFPISKASSIK
                     SKLYSTPDVQAIVKKAIVESLKKSYLEDGLLKEDKEKYPIFVFIHKDKVTISIDTTGD
                     ALHKRGYREKANKAPIRETLAAGLIYLTPWKAGRVLVDPMCGSGTILIEAAMIGINMA
                     PGLNREFISEKWRTLDKKIWWDVRKDAFNKIDNESKFKIYGYDIDEESIDIARENAEI
                     AGVDEYIEFNVGDATQFKSEDEFGFIITNPPYGERLEDKDSVKQLYKELGYAFRKLKN
                     WSYYLITSYEDFEYEFGQKADKKRKLYNGMLKTNFFQYPGPKPPRNNK"
     gene            complement(14838..15656)
                     /gene="larE"
                     /locus_tag="KRH23_001851"
     CDS             complement(14838..15656)
                     /gene="larE"
                     /locus_tag="KRH23_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016783 - sulfurtransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent sacrificial sulfur transferase
                     LarE"
                     /protein_id="HHS5225131.1"
                     /translation="MEVNFVKEKEKLDKLKKMLLELGSVVVAYSGGVDSNFLLKVAKD
                     TLGENVIAVTIHAMMHSSREIEEAKQYTQNFGVKHIILNIENFDLKEFKENGIDRCYH
                     CKKYIFSKIKEVAKEHNIKYIVDGTNIDDLGDYRPGLKALSELGVISPLKDSSLKKEE
                     IRSLSKTLGLNTFNKPSFACLASRIPYGVEITDENLRIVEKSEEYLSNLGFSQFRVRM
                     HGDIARIEVGQEELGKFFENNNFNKVDTKLKIFGFKYVTLDMSGYKMGSMNLNV"
     gene            complement(15927..16628)
                     /locus_tag="KRH23_001852"
     CDS             complement(15927..16628)
                     /locus_tag="KRH23_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4253 domain-containing protein"
                     /protein_id="HHS5225132.1"
                     /translation="MSIEDLYDFECVPLNNEIDIDVLFEKMIEDGKEKEYTPIIVIDE
                     KVGLLRKNIDMITKEYGSLENYREYCLTKYNEIDVNQFFDFRKSEISELLKELIDLED
                     DFYDYKHFRPIMNIDIFYEYNKVYIAKIPTIKPYEVFAYIPIGGFNDCPRDEEHIAIA
                     KYWYEKHGIFPIAIGCDTVQYSIKNLTKDGKKFDDLCIELVFYCEDIIIQGYETLKAL
                     KDVLKRSTIVLFWWD"
     gene            complement(17064..17426)
                     /locus_tag="KRH23_001853"
     CDS             complement(17064..17426)
                     /locus_tag="KRH23_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HHS5225133.1"
                     /translation="MIKLYGYTKCSTVKKAKNWLKENNLEFEDIDMVQSPPSKEELKS
                     IYKTSGYDIKKFFNTSGMKYRELGLKDIVKTESDDKLLEILVSDGMLIKRPLLLDGKN
                     VLLGFKEDVWKSTLLKED"
     gene            complement(17725..18396)
                     /locus_tag="KRH23_001854"
     CDS             complement(17725..18396)
                     /locus_tag="KRH23_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015424 - ABC-type amino acid transporter
                     activity [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HHS5225134.1"
                     /translation="MLKIKNLNKSFKKNRVLKDISFELEEGQIGVLLGKSGAGKTTIL
                     RCINGLEEFDSGEIIIDNEVIKNKRDMAKIRGKIGMVFQNFNLFPHMTVLENIIESPV
                     NVFKVPRKEAEERARELLRLVDLEDKLNSYPFELSGGQQQRVAIARSCALMPKVLCFD
                     EPTSALDIDTIQRVVNIMNRLKDKGMTILIITHDVVFSNNVADKIISIKDGIVENVQI
                     KEKIV"
     gene            complement(18428..19039)
                     /locus_tag="KRH23_001855"
     CDS             complement(18428..19039)
                     /locus_tag="KRH23_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HHS5225135.1"
                     /translation="MLQGLEIVIAMFCITLIVSIPLGIGVAFLRLSKNKLVSGITQCY
                     ILIMRGTPLLLQMIVIFYGLPLLGIVFDRFTAGVVAFFLNYAAYFAEIFRGGIQSIDR
                     GQYEASKVLGFDKFTMYKRVIFPQVFKRILAPISNEVITLVKDTSLVYILGLNDILRI
                     SQIAMNREASLLPLFEAGAIYLIFVAILTKGFELLEKKYSYYR"
     gene            complement(19077..19880)
                     /locus_tag="KRH23_001856"
     CDS             complement(19077..19880)
                     /locus_tag="KRH23_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HHS5225136.1"
                     /translation="MKNILKKVGIFTIMLGLLGGVVGCSKPDNEKDKDASKESKKEVV
                     VGFDNTFVPMGFLDEKGDTVGFDVDLAKETFKRLGMEVKFQPIDWSMKETELNDSKTV
                     DVLWNGYSITDERKKIVSYTEPYLQNKQIIVTLSDSKINSKADLKDKEVGTQQGSTAL
                     DAVEKDKDFMNSLKGGAPVLYDTYDKALRDLEIGRTSAVVGDEVLIRYYMGQKGEDKY
                     KVLKDDFGLEDYVVATSKENPELCEKINETLKEMKKDGTFDKIYDKWFK"
     misc_binding    complement(20006..20268)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(20354..21661)
                     /locus_tag="KRH23_001857"
     CDS             complement(20354..21661)
                     /locus_tag="KRH23_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5225137.1"
                     /translation="MKEIADAITSEYLSYGINEDISIYEGRFCIYLDKKYRCNGKIYY
                     KMTPPISISFKADIGCVEEIDNEDDNLALDYDNAILEVHGYKIISITINTLSEFSVEG
                     YINDDCIKSKNSYVEYVDFNIINLDKIPGKLIKYNDKVYAGRIEFDINDYVVTIDKRY
                     DYRKELKSELKSKSGAIITHIGRIRRKDGRIFRTNNTINLLDRISTALSFMCGRYVGF
                     CLAKGYRSGNEVYRIWNENQISPFRYVPTWSDTLSNYHNMEKYISLMCKKLEDFYYGS
                     AIKSVVDWYIESLGSATMENNIISVQIALETLSYVILVEQNKILTDEAFDCNLASKNI
                     RLLLDTCKIPYGKHELNIFDNIIKNKFDDGVDLVIYLRNSIVHPSRKTHRAVLEVEDI
                     WNIISIGTRYIELVLLFILGYRGEYSNRLVERCYGEVEVVPWN"
     gene            complement(22311..22748)
                     /locus_tag="KRH23_001858"
     CDS             complement(22311..22748)
                     /locus_tag="KRH23_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SufBD protein"
                     /protein_id="HHS5225138.1"
                     /translation="MKNLNLLINKLYSKNHNEAYKAFLFLENESLKSNITYCFFDSFL
                     EMIDNENSYIRTRGLLLISANAQWDIDNKIEINIDSILSHIVDKKPSVSRMFIKSIPN
                     ITKYKENLINRIKMELSNADISIYNNMKPLVEKDINDTLSNIS"
     gene            complement(22954..23331)
                     /locus_tag="KRH23_001859"
     CDS             complement(22954..23331)
                     /locus_tag="KRH23_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C-GCAxxG-C-C family (seleno)protein"
                     /protein_id="HHS5225139.1"
                     /translation="MCDKVIASKYHEKGFNCAESVIKAYNEEFNTDIPVCLGSGLGSG
                     CGVASLCGAVNASNIIIGYVKGRNHEDESTKAKVYAKDLTTTVRKEYGSELCIDLKKD
                     LVACREIMDFAYDSLKETLKKEL"
     gene            complement(23447..23941)
                     /locus_tag="KRH23_001860"
     CDS             complement(23447..23941)
                     /locus_tag="KRH23_001860"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003908 -
                     methylated-DNA-[protein]-cysteine S-methyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HHS5225140.1"
                     /translation="MSLVYDVYKSKLGNLYILSEDGFIVSIYIGDEKFNNLKNECIKK
                     GIDIKRSKEDLKEAISQIDDYFNGKRKVFNLNIRIEGTEFQKSVYREMLKIPYGETLC
                     YSDIARNINNPKSVRAIGQASKSNKIPIIIPCHRVVGKKDIGGYMGNHSDLKEILLNL
                     ERQS"
     gene            complement(24090..28343)
                     /locus_tag="KRH23_001861"
     CDS             complement(24090..28343)
                     /locus_tag="KRH23_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydratase activase-related protein"
                     /protein_id="HHS5225141.1"
                     /translation="MDELFHIGIDVGSTTVKVVVLNNSNNIVHKEYRRHYSDVKKSVK
                     EVLNGIYEKLGDINTTIIITGSGGIGISKKLGVKFVQEVISSTKSIEYFHPETDVVIE
                     LGGEDAKITYLSGGIDQRMNGICAGGTGAFIDQMASLLKTDASGLNELAKGYNVIYPI
                     ASRCGVFAKTDIQPLINDGANQTDIAMSIFNAVVVQTVSVLSCGRKIEGNVAFLGGPL
                     YFLSELREAFKRVLDLKDENIIFPENAQLYIAIGAGLLSVDEDNIQLKSLIEKLDSIK
                     NIEDGEVNLLEPLFKDKNEYEEFSRRHEKEKINYVDINLIKSNCYLGIDAGSTTTKAA
                     LIDEDGRLVYSYYNSNEGNPLKTTIKVINEVYDILPKNIKILSSTVTGYGEGLIKKAL
                     KIDNGEIETIAHYKAAKFFNKDVDFILDIGGQDMKCLKIKDGVIDNIILNEACSSGCG
                     SFLETFASSLSMTIEEFAHEGIYSQNPVDLGSRCTVFMNSRVKQAQKEGASVGDISAG
                     LSYSVIKNALFKVIKIRDLNEIGNNIVVQGGTFYNDLVLRSFEKLIGKNVIRPNISGI
                     MGAFGSALIAKEKYESGYKTSLLSKAELNNIKLEASVTRCKGCSNHCLLTINKFSDNE
                     IFISGNRCEKGEAIYGDKKIGLEKKKPINLFKYKYNRIFRYKPLEKEEAKNGEIGIPR
                     VLNMYEDYPFWFTFFNAMGFRVVLSDRSSKQLYETGITSIASETVCYPGKLVHGHIEN
                     LIAKGIKNIFYPSVTNENKEDSNADNYYNCPVVISYSEVIKNNVENIRNKNINYINPF
                     ISLNDKEKLKKRLYDELSRHFSDIKITKEEVNHAVDKATDEQNLFKMEIQAAGERALK
                     EIKERNMKGIVLCGRPYHIDPEINHGMPELINSLDMAVLTEDSICHLANAQRPLRVVD
                     QWVYHSRLYKAASFVRDKNYLELVQLNSFGCGLDAVTTDQVQEILNEKSKIYTIIKID
                     EGNNLGAAKIRMRSLKAAMFERESKNIDVKNIKVNRIQYAKNNQITNKHTILAPQMSP
                     IHFQFLEKAVNLSGYNIEILKDTDSSVIEEGLRYVNNDACYPAIIVVGQLITALKSGK
                     YDLNNTSVTITQTGGGCRATNYIGFLRKAIYDAGFKDVPVIALSVNGIEDSGIMDNIS
                     LKLINRLFMSVVYGDLLMKVLYRVRPYEKVTGSANALYEKWVDICKSSLVKAKISVFT
                     RNIKNIVKEFDNLEILDIKKPKVGLVGEILVKFHPIANNNLVDILEREGAEAVVPDLT
                     NFFLSCAFNTIYKHTHLEGSRKSRMIGEAFIYITGIYQRVYKKALDKSERFYAPANIK
                     NVAKSTEPVVSLGNQTGEGWLLTGEMVELLNEGVENIICMQPFGCLPNHIIGKGSIKE
                     LKRLYKNANIIPIDYDPSASEVNQLNRIKLMLSKAFKNI"
     gene            complement(28724..29893)
                     /locus_tag="KRH23_001862"
     CDS             complement(28724..29893)
                     /locus_tag="KRH23_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CD0519/CD1768 family membrane protein"
                     /protein_id="HHS5225142.1"
                     /translation="MEKLTDRRQVKAVSMETFIFLILLVVGFGYVGSIMGAGMMFKVI
                     MSTAHALLLETVFLIMAMAVLAGALSALLSEFGVIALINKIFAVFMKPLYGLPGASIA
                     GAITTYLSDNPAIIPFAKDKTFTQYFKQYQVPALCNLGTAFGMGLILTTFMISQGTEY
                     VLPALIGNLGAIIGSVISVRIMLTFTKKFYKYNPEEDKATGTLEKKDEFREIREGNVF
                     QRALDAILEGGKMGVDMGMAIIPGVLVVCTLVMLLTFGPSTDPVTGQEVYTGAAYEGI
                     KLLPVIGDKLGFILEPLFGFTSPEAIAFPITSLGAVGAAMSLVPEFIKSGAITPNDIA
                     VFTAMGMCWSGYLSTHIGMMDALNARQLAGKAILSHTIGGLCAGAAAHFIFTLVG"
     gene            complement(30287..31303)
                     /gene="gap"
                     /locus_tag="KRH23_001863"
     CDS             complement(30287..31303)
                     /gene="gap"
                     /locus_tag="KRH23_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HHS5225143.1"
                     /translation="MKIKVGMNGFGRIGRAVLRIAQEELGDNIEIVAINARATTESLA
                     HLFTYDSCYGTFRGEVEAKDEDTLVVNSKEIKILRYNDPEELPWKELGVDIVIESTGL
                     FTQREKAEKHIKAGAKKVIITAPGKNEDITIVIGVNEKEYDNEKHNIISNASCTTNCL
                     APFAKVLDEKFGIVKGLMTTVHSYTNDQRILDKSHKDLRRARAAAESIIPTTTGAAKA
                     VSRVLPQLEGKLNGFSLRVPTPTVSLVDLVCELKENVTSEQVNSVLKDAAEGELKGVL
                     GYCDKPLVSIDYKGDSRSSIIDALSTMVIEDNMIKVVSWYDNEWGYSSRTVDLVKYVA
                     EKLK"
     gene            complement(31940..32404)
                     /locus_tag="KRH23_001864"
     CDS             complement(31940..32404)
                     /locus_tag="KRH23_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4624 family lipoprotein"
                     /protein_id="HHS5225144.1"
                     /translation="MKKLVIILISIISVVSLTACKKSIESKYNNLNNKESGQTTIEMD
                     LDKNYDTSDPFVNARLFCVSNDIDVLDTEISFKMDGDSGIVEIKDNKTDETLWSNTWH
                     GSVNNDTFTISLSNIQKEKEYAICFTGIKINHAVVKVTFESNLVKEKEKPSK"
     gene            complement(32728..33336)
                     /locus_tag="KRH23_001865"
     CDS             complement(32728..33336)
                     /locus_tag="KRH23_001865"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016817 - hydrolase activity, acting on
                     acid anhydrides [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0009132 - nucleoside diphosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HHS5225145.1"
                     /translation="MKKTIIKNVNPMIENKFIGLFEIEYKNKLDEDKVWMVASRKSSE
                     QLKNIYLKNEEDSVDAVVIVGLHKSSKKLILIRQFRIPINGYIYELPAGLVDEGESID
                     ISVERELREETGLTLLEIKKNKSIDKVYLSPGMSDESVAFVYCICDGDITDEFLEPDE
                     EIEALLISQEDAKEILQSNHKIDTKAFLILQMFVSLGAKLFE"
     gene            complement(33418..34119)
                     /locus_tag="KRH23_001866"
     CDS             complement(33418..34119)
                     /locus_tag="KRH23_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="B3/B4 domain-containing protein"
                     /protein_id="HHS5225146.1"
                     /translation="MKFIVEKEVFDKLENVCFGVVVAKGIDNTKEIERISNLLDISID
                     RVEDYFKDKKVKESEEIIPYREAFRSLGMNPNKFMSSIEAMTTRVAKNKKLPHINPIV
                     DLGNSISLKYLLPMGAHDMDFRNDDVYVRFSKKGDKFVPFGETDVELMEEGELIYSVG
                     DMVKTRRWIWRQGEEGKITNSSKNIFFPIDGFTDANLDKVMSAREELAKLLKEIFNCE
                     IKVGFVDKDNPEMEI"
     gene            34346..34612
                     /locus_tag="KRH23_001867"
     CDS             34346..34612
                     /locus_tag="KRH23_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HHS5225147.1"
                     /translation="MKNFILIYFIVINSIAFFSMYIDKKRAIRNEWRIKEATLMSIAV
                     IGGSIGSIIGMYSFRHKTKHIKFTFGIPFILFLQFLLVYFYILK"
     gene            complement(34715..35134)
                     /locus_tag="KRH23_001868"
     CDS             complement(34715..35134)
                     /locus_tag="KRH23_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjdF family protein"
                     /protein_id="HHS5225148.1"
                     /translation="MDKISGKLTVLFEEPFWVGIFERQDGKKYEACRVVFGAEPKEVE
                     VYEFILERFFSLDFGSIKLEKNVTKDNIGYKRMQRKVKKEQEKETIGTKAQNALKLQY
                     EERKQDRKNLAKNRKEEEKERLFNLKQEKRKAKHKGH"
     gene            complement(35401..36183)
                     /locus_tag="KRH23_001869"
     CDS             complement(35401..36183)
                     /locus_tag="KRH23_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HHS5225149.1"
                     /translation="MEYYIVDSFATKLFKGNPAGVCVLDRRIPLELMQKIAEENNLPE
                     TAFVVKGKGNYELRWFTPKAEIDLCGHATLAAAYVISNFIDVNVKRIDFFTQSGKLEV
                     TRNGNLYEMIFPEIMPIEIELSPQQANLIGCVPSAVYSSRDLILLLNSEQEVINYKPN
                     YAQLRKLTDWLGIIITAQGSNTDFVSRYFCPELDSEDPVTGSSHCNLIPYWSEKLGKH
                     KMVAAQLSNRGGIIQCEVLKDNTVKISGEAVLFMQGTIKIDI"
     gene            complement(36248..37009)
                     /locus_tag="KRH23_001870"
     CDS             complement(36248..37009)
                     /locus_tag="KRH23_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896901.1"
                     /note="N-terminal region resembles flavodoxins. C-terminal
                     ferrodoxin region binds two 4Fe-4S clusters; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EFR1 family ferrodoxin"
                     /protein_id="HHS5225150.1"
                     /translation="MIGIYFSGTGNSRYCVEKFLQEYDITANSYSIEDNELLQHINNH
                     ENIIFSYPVQYSNVPKILKDFIINHSTLWNGKRVFIIATMALFSGDGSGVLSRILKKY
                     GAITVGGLHVKMPDSIGDEKVLKHSLEYNRKLVIKAEKKVTKAAKKLKHGSPPKEGLG
                     FLSHIVGLFGQRLYFINKTNMCTDKLKINTEECIVCGKCVNLCPMKNLVIKNCMIVAN
                     GQCTMCYRCVNNCDKKAITLLGKKVVEQSNIKKYM"
     gene            complement(37514..37648)
                     /locus_tag="KRH23_001871"
     CDS             complement(37514..37648)
                     /locus_tag="KRH23_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5225151.1"
                     /translation="MDLINTIDKVQQAHKPIDEIIKTIRDIVDIIKILELVYNFKSNQ
                     "
     gene            complement(38058..38888)
                     /locus_tag="KRH23_001872"
     CDS             complement(38058..38888)
                     /locus_tag="KRH23_001872"
                     /EC_number="2.1.-.-"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HHS5225152.1"
                     /translation="MLNKLCMYLERPELYKQSEINFWDDEYISKQLLKAHLDTNFEGA
                     SRNFNFIEDSVNWIVTVANPANYPKLLDLGCGPGLYAEKFAQKGYKVTGIDFSKRSIN
                     YAQNRNKETNLNVNYLFQSYLNMNYNEEFDLATLIYCDYGALSTENRRLLMEKIYDSL
                     KPGGKLILDVFTINKYNNFEEIKYWEINEDGGFWSNEKYMCLQDNCKYNDYNTLEQTL
                     VITEKDENVFYVWNHYFSKESFLLEVENIGFKSVEFFSNVKGEAYSDDSMTMGLVLQK
                     "
     gene            complement(39240..40142)
                     /locus_tag="KRH23_001873"
     CDS             complement(39240..40142)
                     /locus_tag="KRH23_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HHS5225153.1"
                     /translation="MYNKIKYIPINCEIACNKLKRSMPYKWDLNIYRGCEHGCKYCYA
                     IYSHKYINSNNYFEEIYVKTNIVEKLERQLKSSKWKKEVINIGGVTDSYQPIEADYKI
                     MPEILNLLIKYKTPAIISTKSDLILRDYDLIDKLSRITYINVASTITTVNEDTQRLIE
                     PNGVDSMRRFKMLKEFRKTNASVGLHIMPIIPYITDDFDNINSLFRHAKECNVHYVLP
                     GTLYLRGITRGVFFDFVKKEFPELFDKLSILYSAGSLNREYKNQLYKMVNELRYKYSL
                     SSSYSKIMKEKLKNSGDVQISFFD"
     gene            complement(40192..40653)
                     /locus_tag="KRH23_001874"
     CDS             complement(40192..40653)
                     /locus_tag="KRH23_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine dimer DNA glycosylase/endonuclease V"
                     /protein_id="HHS5225154.1"
                     /translation="MRLWHKDLIDVLPKNQLVSQWRELLAIKGSIDKKGTPNHLLVNK
                     VLNYSIDEFKFYTKIVHDEMLKRNYKPNELKYTSILKWKNRNFANDISNEHSLNLENL
                     YDDWHNKMYLKQCLYNLEEKATCGGIPINEWNILLCKYSKDYELWSGNIMF"
     gene            complement(40705..41160)
                     /gene="def"
                     /locus_tag="KRH23_001875"
     CDS             complement(40705..41160)
                     /gene="def"
                     /locus_tag="KRH23_001875"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042586 - peptide deformylase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HHS5225155.1"
                     /translation="MAIRKIRTFDDEILRKKSKYVENVDNKIREILNDMAETMYNTPN
                     GGGLAACQVGVLKRLVVIDLGEGLIKLVNPEIIKQEGEQIVVEGCLSFPEVWGKLKRP
                     KKVTVQALNEYGEKIEIKGSGFMAKCLCHEIDHLNGIVFTDKIIEHVKL"
     gene            complement(41132..41410)
                     /locus_tag="KRH23_001876"
     CDS             complement(41132..41410)
                     /locus_tag="KRH23_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HHS5225156.1"
                     /translation="MNGANMKNKIKILREKLGLTQEQLGRLVGTSRQAINAIETGKNE
                     PSIWLAYDISRIFNEPIESVFLFEESERKSRAQISRGEYYGYKKDKNI"
     gene            complement(41492..42208)
                     /locus_tag="KRH23_001877"
     CDS             complement(41492..42208)
                     /locus_tag="KRH23_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHS5225157.1"
                     /translation="MIKIINAFKQEFGQIKRDAMLFIVCVSPILCGVFIKFGIPLIQN
                     ISLNKFYYQLNLEPYFLMFDLLLAFITPFMFFFASTMVILGEIDDSISRYLIVTPLGK
                     TGYLISRFGIPGILAFIITMILLIFFSLTKISLLLNLSISLLVLLQGIIISILVISLS
                     SNKLEGMVITKFSGVFMMGILAPFFILNKAQYILFFLPTFWISKAFKEDNYVYMFISI
                     VISLIWILLLFKKFSKKIVK"
     gene            complement(42205..42888)
                     /locus_tag="KRH23_001878"
     CDS             complement(42205..42888)
                     /locus_tag="KRH23_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHS5225158.1"
                     /translation="MRLKNLILGDIKFQFKYGFYFLYLFLSIIYICIINVFPTFMREK
                     IAIIMIYSDPAAMGLFFMGAIVLLEKSQRVLNSLAVSPVKVSEYILSKVISLGVISSI
                     VAMFIAITLNLDNIIISTIGTFFSSIIFSLLGLIVASKASSLNQFIVLSIPIEIICFI
                     PPILNVLLDTKSYANLYPFNICISLISGDKNFIMINILILISIIIIIYFITYYFICSS
                     WKKVGGVKL"
     gene            complement(42885..43730)
                     /locus_tag="KRH23_001879"
     CDS             complement(42885..43730)
                     /locus_tag="KRH23_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHS5225159.1"
                     /translation="MIKVDDLSFSYTDRDFLQNINFEVGKGEILGFLGPSGAGKSTLQ
                     KILIGMITNYGGSVIVNGVESKRHSNKFYENIGVDFEFPSLYEKLTAIENLKYFGSLY
                     SKKLLSIDELLKSVGLENEANKRVSEYSKGMKSRLNFIKALLHNPDILFLDEPTSGLD
                     PSNSKVMKDIILSEKSKGKTIILTTHNMLDATELCDRVAFIVNGKISALDTPHNLIMS
                     KGAIKVRYTYFDNGEKTSECFLNNTANDKNLNMLIEKNKLLSIHSSEPTLNDIFIEIT
                     GRNLQ"
     gene            complement(43844..44434)
                     /locus_tag="KRH23_001880"
     CDS             complement(43844..44434)
                     /locus_tag="KRH23_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HHS5225160.1"
                     /translation="MPKSYSDKEREYIIKRLKEEARLCMEQYGIRKTTVDELVKRVKI
                     PKGTFYLFFQSKELLFFEVLRDIHDSIQKEILYEINRVDESITCEQLTDIFMKFYRMV
                     DSTSILNLMINGEFEILVRKLPDSIIEEHFRHDDFEIGEIISCIPNAKNKDIESFSGA
                     FRAVFLTMLYKREVGSNCFEDALRLMINGLVIQLME"
     gene            44723..44956
                     /locus_tag="KRH23_001881"
     CDS             44723..44956
                     /locus_tag="KRH23_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HHS5225161.1"
                     /translation="MATTTKNRFYDYVQENLNKYVEVHSYFSSCPLYGEIIEADSLSI
                     TLCSRYIDESNPTLNETYTLYLPLSSIISIRTL"
     gene            complement(45187..47574)
                     /locus_tag="KRH23_001882"
     CDS             complement(45187..47574)
                     /locus_tag="KRH23_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding cysteine protease Cwp13"
                     /protein_id="HHS5225162.1"
                     /translation="MKKFTSKKVTRFVALFLISILVMSTIPVSADNSNTLNQIKKAEY
                     SETYKQYLNDAKNGRTEKYNGIIPNPYQLEGTQIQSKGRTVPTSYDPRKLGLMTSIKN
                     QEDLGICWDFAAMATLESFLKLNNYGDYDLSEEHLRWWASDGEYGWSVNDMNGALNYE
                     AMGYLTSWSGPKLEKDIPYNGRVSKAQGAKKPTNMNTAPTVFNVTDAVCVSNDINSTK
                     NAILQYGAVTSGYYEDIKYQSDDQNSYYCPTKSFNTNHAISIVGWDDNYSKDNFNANI
                     RPSKNGAWLIKNSWGDYNSEGGYFWISYEDKTLMSDIDNFSIKGGKKPNDDEKMYQHD
                     YASIVPLISKKITAANVFDFNRGDETLKSVMFLTESIGAKYEVYYAPVVNGIPQENNM
                     KKLKEGTAQYSGYITVPIDSFDIPEGKGAIVVSIEGKNGESTIGSESNVPGYDTFKAK
                     ANLGESYIIDNTGKFFDINRDSNFYPCNFTIKAVTEKSSGESIPNESLIGSDRYETAI
                     KVSQNGFNSSENVVLVNGSSIVDALAATPFTSAINSPILLTQKEALNSKTKAEIQRLG
                     AKKVYLIGGENSISKEIEQQLKSLNISIERISGSDRYKTSLLLAQKLNGIKNVSQIAV
                     VNGVKGLADAISVGAAAAENNIPIILANEKSELQGADEFLNSLNIEKSYIIGGTASLS
                     NNLESKLKNPTRLSGSSRDETNSKIIDNFYKKDTLKNAFVVKNGIKNQNDLIDGLAVG
                     PLGAKTGSPVILVGDKLADSQKEVLKNKTLEKVTQVGGGANKNAFKELVKLKSAK"
     gene            complement(47758..48513)
                     /locus_tag="KRH23_001883"
     CDS             complement(47758..48513)
                     /locus_tag="KRH23_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008047 - enzyme activator activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydratase activase"
                     /protein_id="HHS5225163.1"
                     /translation="MFSIGVDSGSVATKGVLFDGEKIIKKIIIPTGWSPKSTSKQVYE
                     LLSSEIDKKDIKKVVGTGYGRGVMDFADKKVTEITCHTRGIYFLNKNIRTILDVGGQD
                     SKVINLDRDGNVFNFIMNDKCAAGTGRFLEITSNLLGSDIESIDTLAKGYEPVNISSM
                     CTVFAESEIVSLLAQNISTGEVAAGILKSIANKSTSMLARGEVVDEVAFTGGLAKSKE
                     LVKMIEEILGKKIFIAEDTQIVGALGAAVIGFR"
     gene            complement(48538..49689)
                     /locus_tag="KRH23_001884"
     CDS             complement(48538..49689)
                     /locus_tag="KRH23_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="double-cubane-cluster-containing anaerobic
                     reductase"
                     /protein_id="HHS5225164.1"
                     /translation="MTNLPKQFDSFNEARQKGFINAKELKESGKKMVGVFCTFTPVEI
                     PMAAGATVVGVCGVSEEPIPDAERVLPRNLCPLIKSSYGHAITDTCPYFYFSDLLIGE
                     TTCDGKKKMYEELAKVKPTYVMHLPNTSKGEFAYKLWKDEMIRLKEGVEKSLGVTITE
                     EDIRTAIKDKNEERELLKEFYALGKLQPSALTGLELHNVLYQAGFKFDRAELKHSLRE
                     VIDDMKERYEKGECPVQKDKPRILITGSPIGGISEKIVKTLEDAGASVVAYELCGAIR
                     SNDLLVDEEIEDVYDALTQKYINIGCSCMMNNDNRIELLDRIIDEYNVDAVIDVVLQA
                     CHTFNIESYRIREFVTKEKNKPFMSLETDYSKSDTEQLRTRFEAFVEML"
     gene            complement(49905..50645)
                     /locus_tag="KRH23_001885"
     CDS             complement(49905..50645)
                     /locus_tag="KRH23_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EcsC family protein"
                     /protein_id="HHS5225165.1"
                     /translation="MKDYEDVVYIKLVKKELEEWKKNILKKPSIFDKASKGIQNKFNG
                     VLPDKYHEIITSSIKVMTKTVLFGYKYATKPPLRNMSLEEREKLVLEKAKTYKTTAMI
                     EGAGTGAGGILLGLSDFPLLLGIKVKFLYDVASIYGYDVKDYRERIYILNILQLAFSS
                     QQHINKTFKLMNNWDEYVNSLPEDINDFDWRTFQQEYRDYLDLAKFLQLMPGIGAFVG
                     FYVNGKLIDKLCETAVSAYRLRIRELKL"
     gene            complement(50717..51706)
                     /gene="add"
                     /locus_tag="KRH23_001886"
     CDS             complement(50717..51706)
                     /gene="add"
                     /locus_tag="KRH23_001886"
                     /EC_number="3.5.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004000 - adenosine deaminase activity
                     [Evidence IEA];
                     GO_function: GO:0019239 - deaminase activity [Evidence
                     IEA];
                     GO_process: GO:0043101 - purine-containing compound
                     salvage [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HHS5225166.1"
                     /translation="MFENLPKIDLHCHLDGSVRVETMLDIAIKEKIDLPSNNMDEIKK
                     LAKVSFNCTSLDEYLEKFDLPLKVMQSKENLKRITFELLEDASRENVKYIEIRFAPLL
                     HTQKGMSVKNIIEGIIEGIREAESIYDIKGNLILGCMRTMTSKEALLVIEEGKSFVNK
                     GVVAVDLCGPEKEGFCKEYKDVFKLAREYGYKVTIHAGEAASGENVLDAINILKADRI
                     GHGVKIKDHKKAYNLVKDKKILLELCPTSNVQTKTVDSYEAHPFYTFYKDNLHVSINT
                     DNRTVSDINLSSELNVIFDTFKLGLEDYKIIYRNTVEASFADKETKEYLNSLI"
     gene            51966..53219
                     /locus_tag="KRH23_001887"
     CDS             51966..53219
                     /locus_tag="KRH23_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium/glutamate symporter"
                     /protein_id="HHS5225167.1"
                     /translation="MITLSFDIVQTLTLSIFFFLIGNLLKNKVNFLNDFCIPAPVIGG
                     LLFCFLNLFFKYFNIADISISGNLMPNFITFFFTTIGLEISINLIKKGGSVLFRYWIL
                     CGVLAFCQNILAITISKIIKLEPLLGLMCGNVSMEGGHGYSAAFGLTIENLGIEGAVG
                     VGLSAATIGLIMGGILGCPVAKFLINKYKLKPSSNMDLSIPRYNRNLKIFGSKFFRNK
                     NRIKNNNFSQTITPSVFLEQVLLIFICINTGEIISRCFYITFNILLPSVVTCMFSAVI
                     FRNLNDKINILELNFKLIDFLKELSLGIFLTLSLMNIDLFELSTLLPPILLIVTFQVI
                     FIILFSIFICFRVLGKDFDSAIIISGLIGHGIGATPNALANMSSLTQKYGNSPKAFLV
                     VPLVSGFLLDAISIPCILFFINILT"
     gene            53316..53540
                     /locus_tag="KRH23_001888"
     CDS             53316..53540
                     /locus_tag="KRH23_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046914 - transition metal ion binding
                     [Evidence IEA];
                     GO_process: GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FeoA family protein"
                     /protein_id="HHS5225168.1"
                     /translation="MTVYNLKLGQKGIIDNIAGNEKLMKRLLALGLIDGTEVEVKKIA
                     PLNDPIVIRFRGFDLAIRKSDAKNINLKNN"
     gene            53696..53932
                     /locus_tag="KRH23_001889"
     CDS             53696..53932
                     /locus_tag="KRH23_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5225169.1"
                     /translation="MLLTHIYFNGQFKQTIELYKQAFNATVKTLIEDSGHLLIVHNEI
                     VIHNKFLILNDFGNKNGVSISEGYQPTYKIQTAS"
BASE COUNT        17950 a         9005 c         5469 g        21662 t
ORIGIN      
        1 atatatttct ttataattta taaatttagc cattaattta tacgatttta tataggtaag
       61 catatactct cacttaatat taaataattt acattttttc tatactataa tcatattctt
      121 ttgtcagtta gtaattttca aagtagattg tttcaattaa aatataataa aattgattta
      181 aaaattataa taaactaata cttattaaaa atatcataaa aaaacaagta ttctatcgaa
      241 tgtaaaatac ttgtttctta gaattatttt tgatttttta gcatatcatt tagagcatca
      301 tatgtgaaat ttattatttc ttcacaagtt attttatttt ttttaagaga tacacatatt
      361 tctgagctgt atttatttct tactctattc aatagctctc ttgaatactt ccttgctata
      421 ttttcatcta aattactatt tcgcccattt aaatacccta ttataacaac agcagcattt
      481 acagctccac aaacacttcc aacattcatt ccaaccccca taccacttcc tattgagatt
      541 ggtatatctg tgttgtgttc ctcattataa gactttatta atgcctctgc acaagtgtat
      601 ccttggctat gatatattga tggtcttgtc atttttatac ttcctttcaa attttatttt
      661 atatgttttg ctactttaaa catgctaatg gtctacatat catatatact atttttgtat
      721 ctataaaatc caacctatat tcactataaa taaatttata attttatcaa tttatattac
      781 tttttatata aagttacttt aatttaaagc tttacttgat atgcttttat tatatattaa
      841 attagctcta ttttctgtga cttagtcaca caatctatat ataataattt aatctactct
      901 tttattgtta tacaatagac cattatatat taactttaaa tttttaggca cttactgcac
      961 ttcattcaat taagtcgtat attattatct ttaattcttt gtatttaaac aaaagatttg
     1021 ctaaaataaa aataagtagt actacataaa ttaaaccctt aggaggttgt aaaattgaaa
     1081 aaaatactta taacaggtgc attaggacaa ataggttcag aattaacaat aaagcttaga
     1141 aatgagtatg gagaacaaaa tgtaatcgct agttcaagga gagtaaaaga aggtaatcca
     1201 gtatgtgaat ctggtatatt tgagatatta gatgttacag ataagaatcg tttttttgaa
     1261 attgcaaaaa aatatgatgt agatactata attcatctag catctttact ttctgcagtt
     1321 gctgaaagta aacctctaga agcttggaac ttaaatatga atggattaat aaatggtctt
     1381 gaaatagcca aagaattgga ttgtaaattt tttacaccta gttcaattgc tgcttttggt
     1441 gaaaattctc caaaaaatat gactcctcaa gatacattac aaagacctaa tactatgtat
     1501 ggtgtgacta aagtttctgg agaattacta tgtgattatt atcactcaaa atttggagta
     1561 gacactagag gtgttagatt tccaggtctt atttcttatg ttacgcctcc tggtggagga
     1621 actacagatt atgcagttga tatatattat gaggcattaa aaaataagag atataaatct
     1681 tacatagcag aaggtacaaa aatggatatg atgtatatgc ctgatgcact tcaatcaata
     1741 gtggatttaa tcgaagctcc agctgataaa ctcatccata gaaatgcttt taatattact
     1801 gctatgagct tttctcctga agaaatagct gattctataa aaaaatatat tcctgatttt
     1861 gtgatagaat atgatgtaga ccctataaga caaagtatag ctgattcttg gcctaactct
     1921 ctagacagta gtagtgcagt aaaagaatgg aactttaagt ttagttatga tttagataaa
     1981 atgaccaaag atatgttaga aaaattatca gaaaaaggaa taggcaaata acaacctatc
     2041 atttttatca aaataggcaa tatactccat cctcaatgta agcagggtgg agatataagc
     2101 ctgtaatatg ttaatataag ttaaaaatgg gtaaaaaatt atatagctaa agacttttaa
     2161 tcttaaaata tatctaaata agattcaaaa atgaataata gtattaaaag gaaaggaaaa
     2221 gctactatgt aagtagcagg tactaatatt gctaaattta aaagaaatta gagaggaaat
     2281 cataaaaaaa tacataggtg atagtttaat ttctgaactt acagaggaat taaaaaatat
     2341 acttataaca gatttacagt ctaacccgtt taaaagtaat attgagctca gtataatacc
     2401 agcaaatata gaaatattta aaaagataga aaatatatta atagactcta aagttaattt
     2461 aaaaatgggt tgggaaagaa tacttataaa ttatatctta aaagatttat ttgaattaaa
     2521 ttatgaaata aataaaagtt gtaatgaacc tttgatgttt agagtcatta tatctattga
     2581 ttcttatgat gcttaggctc aataaataat ttacctgagg atgtgcttta gatttatgaa
     2641 atacaagtta tttatagact ttgaatttaa tatactagat gataataaaa ataaaccaaa
     2701 agaatataat ggtgcggaat taatttctat tggtggaatt ttagttgata acgaatttaa
     2761 tacaatagat aattattact ctttagttaa gccaaaatac aataaaatac tttcaaataa
     2821 atgtaaaaat ttaaccaaat tgaaccaact agatatcaat aatgctccta atcttttata
     2881 tgttatggat gatttttata aatggttttg taaatttgat gatgttacaa tatataattg
     2941 gggtgatttt gatatagctg gccttctaac ttcatttaga gtgtataaat atacaggtaa
     3001 atgcttagag ttatttaata tgatgattga cattcaacct tttatatctc aacatattac
     3061 atacaataat agaatcttat ctaagcaaat atctttactg aatatgaaaa aaattttttc
     3121 tgtaaaagga gatattaaac ataactcact ttcagatgct gtggatttaa tgaatgtatg
     3181 taaatgcttt ttctttaact cccctaaaaa tatcgatatt cttgaagaat tatataataa
     3241 attacctgct ctcaaaacac ctttatatta tattccctac tttgaagatg aaaattttga
     3301 actcaaattt gatagaactc cagaagatat aataatatat cttaaacaaa tattaactat
     3361 actaaatata agtaaaaaag aaatttattt taaaaaaaga agtgtattag tgaataactc
     3421 taaaattatt aactttaaaa atctatcttc ttctttcaaa ttaataaaac tcaatgaatt
     3481 tgaagaatat cctgatttta tcttaaaatt aggagataaa aagagttttg ttgaatctgt
     3541 tattaaaata aataaaagta acagaaaatc cataaaaaat ttaatattaa aattatcaaa
     3601 aaaaccttaa atagttgaat ccaattattt aaggtttttt atactttgaa ttaaattttt
     3661 tatataggat atactaacta agtgtaaata ttttttaaag gagtaattga tagatatgac
     3721 agtagtatta ataagaagta ttatattata cataacagtg ctaattgcac ttagagtcat
     3781 gggaaaaggt gaaatagctg aaatgaactg ttttgattta gttataacac tattaattgc
     3841 agaagttgca tctgtcccaa tggaaaataa taatatacca atcataaatg gtgttgcagc
     3901 aatatctgga cttgtaatca tgcagactct aatttcattc ttatcattaa aaagtagaaa
     3961 attaagttca tttttatcag gtaaaccttc tgtattaata gataaaggaa aaattgtata
     4021 taaagagctt aaaaaagaaa gaattagtat agatgaatta ttagaacaac ttaggattca
     4081 aggatacttt aacctaaaag atgtacaata tgctattttg gagactgatg gtaatctaag
     4141 tgttgtacca gcatcaagct acaatagtac tcctccaaga gcttttaatc atttacctat
     4201 cccacttata ctggatggta gaataataaa taaaaatcta gacatagctc aaaaagatac
     4261 taactggtta atgggtattt taaaatctaa tcacatagaa acttttaaag atgttcttat
     4321 ttgtgtttta gatgaaaatg acaaaatatt tattcaaaat aaaaagggtg attaatattg
     4381 aaatctacaa catttgttat actatggact atcttatttg tattatttgg attttatgtt
     4441 aacaataaac tatatgattt tacagaagga tataaagaca atatatctgt tttagaaaaa
     4501 tctatagaaa atgaagattg ggaaaaagct caaaaagaag ctgattcaat atctacgagt
     4561 tggaataaag aaaaaaacca ttggtacaaa gttttaaatc atgagtactt tgatgaaata
     4621 ggattaaggt ttaatattct ggacaaagca atttatactg aaaataaatt aaaatcttta
     4681 gaagaagttg aaagtataaa aacatatttg ggaaatatta ttgaaagtgt taagtttgat
     4741 gtaaactata tattttaata actttaaata aggatataga tggagctaat ctacatcctt
     4801 atttttgtgc ttttataaaa cttacatatt ttttacttcc aaattttcaa caattattat
     4861 tatcaaaata aatcttaaaa gcttctccaa taaacttaga tgcaccatca ccataattct
     4921 tatcagttac ttttatataa ttagaatctt gtaaataaag ctctgacata taatcaaagt
     4981 atctttcacc attgtctatt ttataaaatt cattacttct tttcatttca ttgtctattt
     5041 cttcaacaat gctttgaact tcccttgaag aacaatctct actcaaatct tctacaagtt
     5101 tttcatacaa tgtatttatc tttggttttc tatctcttag ataagtcttt agtacttgtc
     5161 caataaactt acctgctcca cttccatact ttttatctac ttcttctatc cacgtaggat
     5221 ttactagata attttgaacc atatagtacc agttgtcatc accagtatcc atagagaaaa
     5281 tttcataatc ttttttagat atatctgtta tcgcttttgc tatttcttga aggtctgttg
     5341 aagaaggatt cctacttaaa tcttctacaa gctttctata taattctttt aattttggat
     5401 gtttttcttt taaacaatca tttttatatc tatcaaattt ttctcctaaa ttcaatatat
     5461 cactgctaaa atttgttttt atagcttggg caaacttctc aatagttcca tattgtttta
     5521 tagccatttt agcaattttc tcttcattag acttaactct ttctatatat tcattgtatt
     5581 tttctacact accataaatt ttaattacct tattcctatg ctctctttta aattcttcta
     5641 aaacattaaa atactcgctc atatcaaact ctttaaaatc aatatttcct tctcctctta
     5701 gagtttgatt tataagctct atcaattcat ccagtctctt tcgttttaaa ataagtaatt
     5761 ttttttgatt ttttagagct tcaaccttat caaaatattg gcttgacatt atttccttaa
     5821 cctctcttaa aggaatatca atctccttaa aaaataaaat ttgttgaaga gttttaatag
     5881 attcatcatc ataaagtcta tatcctgcat ctgtaatttt atttggtttt aaaagaccta
     5941 tttcatcata ataatgtaat gccctcacac ttattccagt taaatcagaa acttgtttca
     6001 ctgttctcat atccacacct caaattttaa ttttacagcc atcaatacct actaatatat
     6061 tcaagctata ttttcatatt acactattac gtaatgttag ggtcaataat atatttttta
     6121 tacatccaag attaaatatc ctgttttcat atgctctaag acctcagaga acaataacgg
     6181 aagttgttct gtatcatcac atgtttgagt taaataatct attataatat tggatatttt
     6241 atcaattata atagcagttt tatcaaaaat atcagctact tgtataaaag agtcgttttt
     6301 gtattcctcc ccaatactgt tgagcattct actcatttta tcaaatccac ctttaaattg
     6361 aacagtatct ggttctttaa ttcctttgat tgcatttgga attgttggta ctgttccaaa
     6421 aaacataacc atattggtca aaatcttatc ataatcatct ttatccaatt cagtgttcca
     6481 ctgtggcaac tctttaataa acttttcaaa acctttatat cccaaaaatc ctttaggtgg
     6541 atttaaaaac atatcacgct ttatagcaat agcttctcta gcaatgttat atttattctt
     6601 tgaagtattc attcttattg tgcaaatagt attttctttg cttaatccag gggaattgca
     6661 attcatgctt tcacgtaatt tatcataaga aagatgtaat aattctgttc taccacaatc
     6721 atacagatat attccttcat catcatatcc taccattaat atataatgaa aaggaatatg
     6781 ttctttatga tatagtttct tataatatgg tagataatac atatctaaag ctcctaaaat
     6841 aactggatat ccatcatcaa tttcagattt tgctttcttt aatgcttgct catacttttt
     6901 aaactcatga tgtttgtatt caaatccaac aattggtgct aaaaatttat acatctgttt
     6961 tgtccttcca tctcccaaag ctaccattct tttcaaatca gctttatttg ttttcatata
     7021 acaaaatgaa ccaaaacctg acagtaaaaa gaaaaaatcg tttggaaggc attcaccggt
     7081 tttatttata tataaatctt ctataccatt ccacatacac tcataatcat gtgaatgatg
     7141 tttaatttca attatttttc tcatataatc tatctcctca ctataaattt tcattagatt
     7201 cagtataaac cctcttacaa tgagagagtc aataactatt gtatttataa aatttatatt
     7261 ttaggtttta tattttcaca ttattaagtc atttggaact ataatatatt tttttatact
     7321 atttactgta taatttaata aattcaaata aaaaaagagc atataaaaac ctaaaaatag
     7381 tttttataca ctcttaaata atttatttta ttattttcca gctttcatag ctctgatttt
     7441 taatggtaaa gtgaataaat taataaatcc ttctgcatct ttgtggtcat aaagttcact
     7501 atttccaaaa gaagatattc cttcatcata aagagcattt tcagtaaata ttccagcagg
     7561 ttttatattt cctttgtaaa gtttaacttt tactgttcct gtaacattat cttgagtttg
     7621 ttccataaat gcatctatag attctcttaa tttacaatac catagtccat tgtaaataag
     7681 ttctccgtat ttataagata ccatttgttt gaaatgtaat gtatctttgt ctaaagtagc
     7741 actttctaaa atattatgtg cttcataaag gattgttcct cctggagtct catatatacc
     7801 tcttgatttc ataccaacaa gtctattctc aactatatct ataacaccaa ttccatgttt
     7861 acaacccaac tcatttaact tatgaatcag tgcaactgga gataattctt caccatttac
     7921 ctttttaggt acaccttttt caaagtaaac ttctacatat tcagctacat cacatgcatc
     7981 ttctgggtct acacattgtt tataaacatc ttttttatgt tcattttcta ggtgctctat
     8041 atctccacct tctgttgaaa catgccaaag gttagcatct actgaatata ttttagcttt
     8101 agttgctgtt acctttatat tatgtttttc agcatagtct atagcatctt ctcttgattt
     8161 tatatcccaa attctccaag gtgcaataac ttttatagtc gggtcaaggg ctgcaattgt
     8221 agcttcaaat ctaacttggt cattaccttt tcctgtacat ccatggcata tatattttgc
     8281 accttcttta tgagcaactt caactaattt tttagctatt ataggtcttg ctaaagaagt
     8341 tcctaataag tattttcctt catatttagc ctctgctttt acggctttaa atatagtttc
     8401 agttacaaat tcttcactta tatcatccac atatgccttt gatgctccac tttgtaaagc
     8461 tttttcatat acatcttcca ttttatcttc ctgacctaca tttccacaaa cagctataac
     8521 atctatatct tcataatttt cctttaacca aggtattatg attgatgtgt caagtcctcc
     8581 tgaatatgct aatactactt tttccttcat ttttaattcc tcccaatctt aaattataat
     8641 ttttatttta tagaaattct taatattgaa tgactctgag aatttagact cacataaaat
     8701 cattttaata ctaaaaaaac cccttagtat tttaaaatac taagaggcga aatatccgcg
     8761 gtaccactct tattgataaa cttagctaat caattagtaa atgttcaaca taccagataa
     8821 acactaataa ttaaatatat taaaaaacgc ctcttggaaa aaccaagaga cgaaatatat
     8881 ccgcgttacc actctaattg ataagataaa cttatccact ctttctctta aggcgagatt
     8941 acctactaac atactaaatt caattagtat cctccaaagt tcttttcact aatacttatt
     9001 tgctaagctt ccaccatcct cagctctcta taaaacacat agaagttact ctctttctca
     9061 caggatttaa atataaagtt ttatatctct cttataaaat atataatagt ttatttttcc
     9121 atttatgtca actatataat ttattttatt tttattttaa agagagtttt atataattga
     9181 ctaatatgtt actttccaaa gacatagtcc tttagctggt gcagtatctg atgattgaca
     9241 tctatctttt gattcaagca tatacttaat atcttgtgga gctcttcttt ttagaccaac
     9301 atctatcaat gcacctacta ttatccttac catgttatac aaaaatccat ttccttctac
     9361 atatatttct ataacattat catcttcttt tatatttata gaataaattt ctcttacatt
     9421 tgattttttc ttagatttag aagaagcaaa actagtaaaa tcatgttctc ctactaaata
     9481 ctcacttgct tttctcattc tatctaaatc taatttttta cttacatgag tagcatattt
     9541 tcttataaaa ggattatgat acttattatt gtcaatttta tacatataag tctttgactt
     9601 tacattgtat cttgaatgaa atctttcatc aacttcttca acagttttta caactatatc
     9661 ttctggtaaa tattcatata aatatttttg aattttatcc aaagaatcca tacaattagt
     9721 tctaaaattt accacttgtc ctcttgcatg agctcccata tcagttcttc cagaacctat
     9781 tatctccact gtttcattag tcattttact taaaacattt tcaagttttt cttgaatagt
     9841 catattattg tcacctaatt tttgatatcc tttatatctt gaaccatcgt atgctactat
     9901 catttttatg tttctcatct taatcctctt tctaagaatt tatgcttgtt tagcaaattt
     9961 attttttata ttaaaagtta tttttgttcc aacattcttt tcactttcta ttttcattct
    10021 tccaccatga agttttacaa tttcattact aattgctagt cctaatccac taccagcctt
    10081 attataatct tcttggaaaa atttatctaa cactttattt aaattttgct tttctatacc
    10141 tgaaccatta tcctctactg atatggttgt tatctcttca tcttgagaag ctacaacttt
    10201 tatgtaacca ccttgactcg taaatttaaa tgaattttgt attaaattta tgagaacctg
    10261 tcttaatcta tttttatctc cttgaatgtt ctctataaat tcattttcaa attcaaataa
    10321 aagtgatata tctttttcag ctgctttaac tttaagttga tttacaacac ctacaattaa
    10381 accttcaaca tcaactatat caacatgaag ttttatcctg tctgaagaaa gccttgaaaa
    10441 gtctaataat tcttcaacta gttttataag tctttctgtt tcatcttgta taatgcctaa
    10501 acctaagtct agttcttctc ttgttatact ttcataacct aaggtttcac tccacccctt
    10561 tatagatgta agaggagtcc ttagttcatg agatacagat gatataaatt cctcttttaa
    10621 tttttcactt ttgtcaatct catgtgccat gtgttcaaat gtctgtgcta aatcaccaat
    10681 ttcatcatct acaatcttca tcttttctaa ttttatatta taatttccta cagccaattc
    10741 atttgcaaat ttctttagct ctcgtaatgg ttttataaga gtctcagcaa atttaagact
    10801 tattagtata gctataataa gtataaatat tcctgctaat ataagccatg tagcttgctt
    10861 taatatcgca ttatcaatag catctaatga tactgtatat ctaacaacac cttctattat
    10921 attatttacc ttaagtggta aggagatact cataacatgc tcccctgtat ctggtattct
    10981 ataagtataa ggtgttaaat ttttagtttt tatatctttt aatgcattgt taacatcttc
    11041 atagtttgct ttttctttac ttttaaaacc atattggtct aatataatat ttttatcttt
    11101 atctattatt gaaattccaa attctgaatt tttagttaag ggttgtttat caaatatatt
    11161 ttttactttt ttctcaaaac ttgtagtttc cattgtaata gcattatatt catcagcata
    11221 ttttatttca gattcaagta gctgtttgac agaatcataa tagtagtttt gtatgtaaaa
    11281 catgaacaat ccttcaaaca gagtaaccat tataataatt attataaaat agttttttat
    11341 tacttttttt ctcagacctt caaaatgtaa cactattatt cttcctttct aaaacagtat
    11401 ccataacccc aaatagtttg tatatatttt ggttttgatg ggtcatcttc tattttattt
    11461 cttatccttc ttatatttac atctactatt ttaaaatcat ataaatagtt agttccccat
    11521 acttcgtcta atatctggtc tctacttaac gactgcttag catttgatat tagatatttc
    11581 actattgaaa attcagttgg tgtaagctca atttcctttc catttttaaa taattttctt
    11641 ttgtctatat caagtataaa tggtggagaa actatctcac tcgacttaac acttgaatca
    11701 tcctttgcta ctcttctaag aagagcagaa actctgacta aaagctcttt tatactaaat
    11761 ggttttatga tgtaatcatc tgctcctgag ataaatcctt ctattttatc atcttcttga
    11821 gctttagcag taagcattat tatacctact tggtcaaaat tctcccttat aaatttacat
    11881 acttctatac cacttatatc tggaagcatt acatctaaaa gagctattgt aatatccttt
    11941 tctgttgtca ttttttctat agcttctctt ccagtacctg cctcaactat ttcatagcct
    12001 tcccttttta agtttatact aacaaaactt ctaataccaa tttcatcttc tagtataagt
    12061 atcttttcct tcataaaata aaacctccaa ttgagtataa tattaaccat atattaatga
    12121 gaaatattct tttaatgcgt ctatagtcat atctagctta tccatttcat ttgcattgtt
    12181 tacaactagt aagaaagtat attcatcgct ctcttgaagt acaatagaat tttgagtacc
    12241 tgtatttttt ctatcttcaa gtttattttt actctctact actatattaa ataaattctt
    12301 acggtctgaa tagtcaaaat agtaaaattt aaatactgct ttttctccaa caaattcctg
    12361 ttcaacaagt attttatcaa ataaattatt tggaataaat aatttaaaat tatatttata
    12421 attataatat atctgacttg taaatattaa acttgagtca gcaccttctt ttccattcca
    12481 tctataccaa cttatagttg cagatgattt agaactataa gtatttttat tattacctgt
    12541 actgcctgca actataggta tttctataat cttatctttg tcaatatcat ctacaggtat
    12601 ataataagat ttagtaatag ttttatcata atcactaaaa gctttgttaa ttttcccatc
    12661 tttcatataa agtatctgcg taatatagtt attatctttc aatataggaa tatcaagtac
    12721 aatacctttt atagctgcag aagaatttcc aatagatgaa gcaacattac ctaatgttat
    12781 atataattca cttaagtttt ttacattttc aaacttaaca gaatctttga ttttcatttt
    12841 cccatcaaaa tttgcaacac ttgcaaacat ttcattagtc ttattattca aatgaagcat
    12901 caatatgtct aacttgtcat ctccatctat atatccaatt tttactttca tgtcattaaa
    12961 atcttcttta ttttgaagcc atgatgcatc caagtcatat atttttgtta tttcattatc
    13021 tactacttta tatatatgca tattcgtttt gtctttggat ttaaccaata agataacttc
    13081 cttatatcca tctgagtcca aatcataaaa attagcatat tctattgatt cgccattttc
    13141 taaaaaatgg tctccaagta cgtatttttc tccattgtaa ctcaaggtta caaaccctac
    13201 ctgactcaca ttattactta aatcttcttt ttgttcaaat actactaatt catcaattcc
    13261 atcgctgttt aaatctacct tatttatttt tcctacttct tttgtattag aaggcaatat
    13321 catagatgaa tctggtttta gtaactggtc aataccatca tacaatactt tttttgtatc
    13381 atcatagtca ggtatcttcg ctaattgttc tggagattcg gtttttatat tacatccagt
    13441 aacaaataac atcatcaggg ctactacagt aataagcttt aacactttca tttaactcct
    13501 cctaatccta taaatcttta aatctttaaa tttgttcaca aaaatctcct cacaataatt
    13561 agacgtttca aggcatcata atgttttact tattttaata aaattttata ttttacaaat
    13621 aaatcatgta aaacttattt attatttcta ggaggcttag gacccggata ttggaaaaag
    13681 ttagttttta acataccatt atacaatttt ctttttttat ctgctttttg cccaaactca
    13741 tattcgaagt cttcataaga agttatcaaa taatacgacc aattttttaa ttttctaaat
    13801 gcataaccaa gctccttata caactgttta acactgtctt tatcttctaa tctttctccg
    13861 taaggaggat tagtgattat aaatccaaac tcatcttcac ttttaaattg agttgcatct
    13921 cctacattaa actctatata ttcatctaca cctgctattt cagcattttc tctagctata
    13981 tctatagatt cttcatctat atcatatcca taaattttaa atttagattc attatctatc
    14041 ttattaaaag catcttttct tacatcccac catattttct tatcaagagt tctccacttt
    14101 tctgatataa actctctatt taagccaggt gccatattta taccaatcat agcagcttca
    14161 atcaatatag taccagaacc acacataggg tctactaaaa ctctacctgc tttccaggga
    14221 gttaaataaa taagcccagc agctaaagtc tctcttattg gagctttatt tgccttttct
    14281 ctatatcctc tcttatgcaa agcatctcct gttgtatcta tagaaatggt tactttatct
    14341 ttgtgtataa atacaaaaat agggtatttc tccttatctt ctttaagcaa accatcctcc
    14401 aaataacttt tctttaagct ttctactata gcctttttta ctatggcttg tacatctggt
    14461 gtactgtata attttgattt tatagaggaa gcttttgata taggaaattg agctccataa
    14521 ggtatatatc tagaccagtt tattcttttt gtattttcaa ataattcatc aaagcttttt
    14581 gcctcaaatt cagcaatttt aagatgtact ctttcagcac atctcaacca catgtttgac
    14641 tttgctattc caaactcatc agttttatat gttattcttc catcttctgt ttttattatt
    14701 tcatatccta aattagtaat ctctctagcc agcatttttt ccattccaaa aaaacatggc
    14761 gatattaacg tataattttt cataaaacct cctgtttcct tatattaact ataaaactta
    14821 tttattttta aaataatcta cacatttaaa ttcatacttc ccattttata tcctgacata
    14881 tctagtgtaa catatttaaa gccaaatatt tttaatttag tatcaacttt attaaaattg
    14941 ttattttcaa aaaatttacc tagttcttcc tgtccaactt ctattctagc tatatctcca
    15001 tgcattctca ctctaaattg agaaaaacct aaattggata gatattcttc actcttttct
    15061 actattctta aattttcatc tgttatttca actccataag gtatcctact cgcaagacat
    15121 gcaaatgatg gtttattaaa agtatttaat cctaatgttt ttgaaagcga cctaatttct
    15181 tcttttttta aactactatc ttttaatgga ctaattactc ctaattcact caatgcctta
    15241 agcccaggtc tatagtctcc taaatcatct atatttgttc catctactat gtactttata
    15301 ttatgttctt ttgctacctc ttttatttta gagaatatat attttttaca atgataacat
    15361 ctatcaatac cattttcttt aaattctttt aaatcaaagt tttctatatt taatatgata
    15421 tgtttaacac caaaattttg agtatattgt ttagcctctt caatttccct acttgaatgc
    15481 atcattgcat gaatggtcac agctataaca ttttcaccta atgtatcttt tgcgacctta
    15541 agcaaaaaat tactatctac tccaccagaa taagcaacta caacactgcc taattcaagt
    15601 aacatttttt ttaatttatc taatttttct ttttccttca caaaatttac ctccatatct
    15661 ggaaaaatat gaactataaa actatatatt atttttttac attcttaatg attataacat
    15721 ataaagtatt tattttataa attataatta cctttaaatc tattaattat aatattaaaa
    15781 atattaaagt atttttttaa cctttgtaat ttaaacatat tactatgcta cactgtgtat
    15841 aaaaacctag tttgacacac tccccataac taaagcaagt ggattcttgg tgactaacaa
    15901 tttaatgctg tctaagtgat agaatatcaa tcccaccaaa aaagcactat tgtagagcgt
    15961 tttaatacat ccttaagagc ctttaaggtt tcataccctt gtataataat atcctcacaa
    16021 taaaatacta attcaataca taagtcatca aattttttac catctttagt taaatttttt
    16081 atagaatatt gaactgtatc acatccaatt gcgattggaa agattccatg cttttcatac
    16141 caatattttg caatagctat atgttcttca tctctaggac aatcattaaa tccgccaata
    16201 ggtatgtatg caaatacttc atatggttta attgttggaa ttttagctat gtaaactttg
    16261 ttatattcat aaaatatatc tatattcata attggtctaa aatgtttata atcataaaaa
    16321 tcatcttcta aatcaattag ctcctttaat aattctgaaa tctcactctt cctaaaatca
    16381 aaaaattgat ttacatcaat ttcattatat tttgttaaac aatactccct atagttttca
    16441 agagaaccat actctttagt aatcatatct atattttttc ttaatagccc tactttttca
    16501 tcaatgacta taattggtgt atattctttt tcttttccat cttctatcat cttttcaaat
    16561 aaaacatcaa tatcaatctc attgttcaaa ggaacacatt caaaatcata taaatcttca
    16621 atactcatat ttatctccta ttctttttag atttaatttt ttgaaagttt tatttttgtt
    16681 gtcagatttt taataccact attatttaaa ctataaatat agaggcaatt tacaaaatat
    16741 acttatataa agaaaagatt catttctttt ttctatataa aactgtatga acaagatatt
    16801 ttttatgaca attcccttat ataaatatga tagcacaaaa caaatgttca tggttaataa
    16861 taagtaattt tgtaacaatt cgttgtaata ttataatatt ttaatataaa atatatgata
    16921 taatttgtaa taagaagtaa tatgtttgtt gatatgaatt tttttgattt gaatttgcta
    16981 attaatattt ataaaaatta gatttaatac ataaatttat aggtgtatta attaataatt
    17041 ttaatcaaca cacctatctc ttcctaatct tcttttagca aagtactttt ccatacatct
    17101 tctttaaagc ccaataatac atttttacca tccaaaagta atggtctttt aataagcata
    17161 ccatcactta ccaatatttc taaaagttta tcatcagatt cagtttttac aatatcttta
    17221 agacccaatt ctctatattt cataccactt gtattaaaaa atttctttat atcatatcca
    17281 ctagtcttat aaattgattt taactcctct ttactaggag ggctttgaac catatctata
    17341 tcttcaaatt ctaaattatt ttccttaagc caatttttag cttttttaac agtagagcat
    17401 tttgtatatc catataattt aatcatttta taaaaattcc tttctaattt tttattgtta
    17461 tacccataaa ttgtatacta taaccaattt atatcataat cattataagc tttcaacata
    17521 aaaaattatc atatttcaaa ttattaaaca tttattcaca ttatatattt aaatagtcct
    17581 tttattttta ttataaatta taatgtaact taaacataaa atataagatt aaattttgag
    17641 ataacaaaag ggcatagtat atttgatttt actcgccctt tatttatatt ataaaattct
    17701 accctagttt atatttataa aactctaaac aattttttct tttatttgaa cattttctac
    17761 tataccatct tttatactta taattttatc tgcaacatta tttgagaaga caacatcatg
    17821 tgtaattatt aatattgtca tacctttgtc tttaagtcta ttcattatat tgactactct
    17881 ttgaatagta tcaatatcaa gtgcagaagt aggttcatca aaacaaagga cttttggcat
    17941 caatgcacat gacctagcta tagcaactct ctgttgctgt cctcctgaca attcaaatgg
    18001 ataagaattt aatttatctt ctaaatcaac taatcttaaa agttctctag ccctctcttc
    18061 agcctctttt ctaggaactt taaaaacatt aactggggat tcaattatat tttcaaggac
    18121 tgtcatatga ggaaataagt tgaaattttg aaaaaccata cctatttttc ctcgtatttt
    18181 tgccatatct ctcttatttt ttattacctc attatctatt ataatctctc cactatcaaa
    18241 ttcttcaaga ccatttatac accttaatat tgtggtcttt cctgcaccag acttaccaag
    18301 taaaactcca atctgacctt cttctaactc aaaagaaata tctttaagta ctctattttt
    18361 tttaaatgat ttatttaagt ttttgatttt caacatataa aaaacctcct cctataatat
    18421 tgtaacttta tctataataa gaatattttt tttcaagtaa ttcaaatccc ttagtaagta
    18481 tagctacaaa tataagatat attgctcctg cctcaaataa tggtaacaga cttgcttccc
    18541 tgttcattgc tatttgagat attcttaaaa tatcatttaa tcctaatata tatactaaag
    18601 atgtatcttt tactaatgtg attacttcat ttgaaatagg tgctagtatt cttttaaaaa
    18661 cttgtggaaa gattactctc ttatacatag taaatttatc aaatcctagt acttttgaag
    18721 cttcatattg tcctctatcg attgactgta ttccacctct aaatatttct gcaaaatatg
    18781 ctgcataatt taagaagaaa gctactactc cagctgtaaa tctgtcaaat acaattccta
    18841 aaagaggtaa tccgtaaaat atgactatca tttgcaaaag taaaggtgta cctctcatta
    18901 tcaatatata acattgtgta ataccactta ctaatttatt ctttgataat cttaaaaatg
    18961 caactccaat ccccaatgga attgatacta tcaatgttat acaaaacatt gctataacta
    19021 tctctaaacc ttgtaacatg cctttagtgc ccccttctta acagctaact tatcttctat
    19081 ttaaaccact tatcataaat tttgtcaaaa gttccatctt ttttcatttc ttttaatgtt
    19141 tcatttattt tctcacaaag ttctggattt tctttagaag ttgctacaac ataatcttct
    19201 aatccaaaat cgtcttttaa taccttgtat ttgtcttcac ccttttgtcc catatagtat
    19261 ctaattaaaa cttcatcacc aacaactgca ctagttctac ctatctctaa atctctaagt
    19321 gctttatcat aagtatcata aagaactggt gctccacctt ttaagctatt cataaaatct
    19381 ttatcctttt ccactgcatc aagtgctgtt gaaccttgtt gtgttccaac ttctttatct
    19441 tttaaatcag cttttgaatt tatttttgaa tcacttagag taactattat ctgtttattt
    19501 tgtaaatatg gttctgtata tgatactatt ttctttcttt cgtctgttat agaatatcca
    19561 ttccataata catctacagt ttttgaatca tttaattcag tttccttcat tgaccaatct
    19621 ataggctgaa acttaacttc cattccaagt cttttaaatg tttctttagc taagtctacg
    19681 tcaaagccta ctgtatctcc cttttcatct aaaaatccca ttggtacaaa cgtattatca
    19741 aaccctacaa ctacttcttt tttagattcc tttgaagcat ccttatcttt ttcattatct
    19801 ggttttgaac aacctacaac tccacctaat aaacctaaca taattgtaaa tattcctact
    19861 ttttttaata tatttttcat aatattctcc ctcgtctttt aatttttaaa atattttgat
    19921 tattttttaa aaagtgtatc tattgcaata taattctctg cgcgcttaaa aaattatatt
    19981 aaaaaactcc cgcctctagc ttctgctaga ggacgggagt taactctcgt ggttccacct
    20041 ctgttcatta atgcctcacg acactaacct ctttaagtac aataaaatta ttatactcta
    20101 gcactataac gggtgcaagg attccggaaa tctcctaata aagtatttct actctttcag
    20161 agtcctgctc aaagatgtgt tcaaagtaaa atctattgct cctctcacca atcggaaact
    20221 ctctgtttaa gattaactac ttttactatt tcttttctta gcatttaatg ttattctgaa
    20281 ttattattat gatattgatt ttatagcata aggcaatata tgtcaatata tattttaaaa
    20341 taaatataaa aatctagttc caaggtacaa cttccacttc accataacat ctttctacta
    20401 atctgtttga atattctcct ctataaccta aaataaagag taaaacaagt tcaatatatc
    20461 tcgttcctat tgaaattata ttccaaatat cttcaacctc taacacagct ctatgagtct
    20521 ttctacttgg atgaactatg ctatttctta aataaataac taaatccact ccatcatcaa
    20581 atttattttt tattatatta tcaaatatat ttaattcatg tttaccatat ggtatcttac
    20641 atgtatcaag taagagtctt atatttttag atgccaaatt acagtcaaat gcttcatctg
    20701 taagtatctt attttgttcc actagaatta catatgacaa agtttcaagt gcaatttgta
    20761 cagatattat attgttttcc atggtagcac ttccaagaga ttctatgtac caatcaacaa
    20821 cactctttat agcagaacca taataaaaat cttctagctt tttacacata aggcttatat
    20881 atttttccat attatgataa tttgaaagtg tatctgacca tgttggtaca tatctaaaag
    20941 gagatatttg attttcattc catattctat aaacttcatt accacttcta taccctttgg
    21001 ccaaacaaaa ccctacatat cttccacaca taaaactcaa agctgttgat atcctatcta
    21061 aaagatttat tgtattattt gttctaaaaa ttctaccatc ttttcttcta atcctaccta
    21121 tatgagttat tattgctcca gatttagact ttaattctga ttttaattct tttctataat
    21181 catatcgctt gtctatagtt acaacataat catttatatc aaattcaatt ctacctgcgt
    21241 ataccttatc attgtattta atgagttttc caggtatttt atctaagttt attatattaa
    21301 aatctacata ttcaacatag gagttcttag attttatgca gtcatcattg atataacctt
    21361 ctacactaaa ttcacttaaa gtatttattg ttatagaaat aattttatat ccatgaactt
    21421 caagaatagc attatcataa tctaaagcta aattgtcatc ttcattgtct atctcttcaa
    21481 cacaacctat gtctgcttta aaacttatag atattggagg tgtcatttta taataaattt
    21541 tcccattaca tctatatttt ttatctaaat atatgcaaaa tctaccttca tagatactaa
    21601 tatcttcatt gataccatag cttaaatact ctgatgttat agcatcagca atttctttca
    21661 tttttattcc cacctttgct tttatgtaaa actcaatata ttatattata taatttaatt
    21721 tatataattt aatatattat tttcattaat tatatacctc aataaatttc tataaaaata
    21781 gtatcatttt agtatcatca tttatttaat acattatgta ttccgtttag atttagttat
    21841 ccgaaaactt agataactag cttgaaattt ctacagatta ttacatactt tattgtaatt
    21901 atatcataat gttataatta catattatca aattacacac tatcttttat tcatatagat
    21961 attatcatcc ttgtgtatat attgtcaaag aaaacattta atttacaaca tattttatat
    22021 catatcatct aaactattat atacacctta tctaattcac acattaacac tattgtactt
    22081 tttctaaaaa tttttaaata aaaatgacag ctttaattta ttattttaaa actgccatta
    22141 aactgtaaat attccctttt agtatacaaa attttacctt tatgttaata tattttactt
    22201 atataaattt ttcataatta atttatacat ataaattagc accattgttg ttttattatc
    22261 ttagttataa ataattgtaa ctagataata ttcaatttct atattaatat ttaactaata
    22321 ttagataatg tatcgtttat atccttttct actaatggtt tcatattatt ataaatactt
    22381 atatctgcat tacttaattc catttttatg cgattaataa gattttcttt atactttgta
    22441 atattaggta tggatttaat aaacattctt gatacagaag gttttttatc tacgatatga
    22501 cttagtatac tatctatatt tatttcaatt ttattatcaa tatcccactg agcatttgca
    22561 gagattaata acaatcccct tgttcgaata tatgagtttt cgttatcaat catttctagg
    22621 aatgagtcaa aaaaacaata tgtaatattt gattttaaac tttcattttc taagaataaa
    22681 aaagctttat atgcttcatt atgatttttt gaatataatt tattaataag taaattgaga
    22741 ttcttcaatc ttctcatctc cctcattaca aatatttatt taaacaaagt ataacatatt
    22801 caaaactaaa tataaataaa aactatatta aataaaaagc ctaaaattat ttgctgttta
    22861 tttacaaata ataattctaa aatatatttg atttatttag tatcggctat aaaaataagc
    22921 tatcaaataa tttatatttg atagcttatt ttcttataat tcttttttta aagtttcctt
    22981 tagactatca tatgcgaaat ccattatttc tctacaagca actaaatctt tttttaggtc
    23041 tatacataac tctgaaccat actcttttct tactgttgta gttaaatctt tagcatatac
    23101 tttagcttta gtactttcat cttcgtggtt tctgcctttt acatatccaa ttattatatt
    23161 tgatgcattt actgcaccac ataaactagc aaccccacac cctgaaccca gtccacttcc
    23221 taaacaaact ggtatatctg tattaaattc ctcattatat gcttttataa ctgattctgc
    23281 acaattaaat cccttctcat gatattttga tgctataact ttatcacaca ttaaaatccc
    23341 ccctcatttt tgtaaattaa aataaattcc ttattatttt tgtaaaaaat acttcttttt
    23401 actattatta tatcaaatat taacaataaa aacatttctt tctaagttaa ctctgtcttt
    23461 ctaaatttaa tagtatctct ttcaaatcag aatgattccc catatatcca ccaatatctt
    23521 ttttgccaac tactctatga caaggtatta ttattggaat tttattactt ttacttgctt
    23581 gccctattgc tcttactgat tttggattgt ttatatttct tgctatatct gaataacaca
    23641 atgtttctcc ataaggtatt tttaacattt ccctataaac tgatttttga aattcagtcc
    23701 cttcaatacg aatatttaaa ttaaagactt ttctttttcc attaaagtaa tcatctatct
    23761 ggcttattgc ttcctttaaa tcttccttac ttctctttat atcaattcct tttttaatac
    23821 attcattttt taaattatta aatttttcat ctcctatgta tatactaact ataaaaccat
    23881 cttcacttaa tatgtacaaa tttcctaatt ttgatttata aacatcatat actaaactca
    23941 tattacttcc cccctttaat atcagtatac atataatttt ttaactaata aagagttacc
    24001 ctaaaaaata ggataactct tttttataga tacttaatat agagtatatt tttaaattca
    24061 ttaactttta acatatcaaa atataaatct tatatatttt taaaagcctt agaaagcata
    24121 agttttatcc tgttaagttg atttacctca cttgcagaag ggtcataatc aataggtatt
    24181 atatttgcat ttttatacaa cctctttaat tcttttatag aacccttacc aattatgtga
    24241 ttaggtaaac atccaaaagg ttgcatacaa ataatgtttt ctacaccttc atttaataat
    24301 tcaaccatct cacctgttaa aagccaacct tctccagttt gattacctaa tgacactact
    24361 ggttctgtac ttttagcaac attttttata ttggctggag cataaaatct ctcactctta
    24421 tcaagtgctt ttttatatac tctttgatat attccagtta tgtatataaa tgcttctcct
    24481 atcattctac tctttctact tccttctaaa tgagtgtgtt tgtatatagt attaaaggca
    24541 caacttaaga agaaatttgt aaggtctggc acgactgctt cagcaccttc tcgctctaat
    24601 atatctacta aattattatt tgcaattgga tggaatttca ccaatatttc tccaaccaaa
    24661 cctacttttg gttttttgat atctagtatc tctaaattat caaattcttt tactatattt
    24721 tttatatttc tagtaaatac agaaattttt gctttaacaa gagaagattt gcatatatca
    24781 acccattttt catatagagc atttgcactt ccagtaactt tttcatatgg tcttactcta
    24841 tatagtactt tcatcagcaa atcaccataa acaacagaca taaagagtct attgattaat
    24901 tttagtgata tattatccat tataccacta tcttctattc catttacact aagtgcaatg
    24961 acaggaacat ctttaaatcc agcatcatat atagcctttc ttaagaatcc aatataattt
    25021 gtagctctac aacctccacc agtctgagtt atagtaacag aagtgttatt taaatcatat
    25081 ttgccagatt ttaatgctgt tattagctga cctacaacta ttatagctgg ataacatgca
    25141 tcattattta catatcttaa cccttcttca attacactac tatcagtatc ttttagaatt
    25201 tctatattat aaccacttaa gttaacagct ttttcaagga attggaaatg tattggagac
    25261 atttgtggtg ctaatatagt atgtttgttc gttatctgat tatttttagc atactgtatc
    25321 ctgtttacct ttatattttt tacatctata tttttgcttt ctctctcaaa catagctgct
    25381 tttaaggacc tcatccttat cttagctgct cctaaattgt tgccttcgtc aatctttata
    25441 atagtatata tcttcgattt ttcattaagt atttcttgaa cctggtctgt agttactgca
    25501 tctaatccac agccaaatga attaagttga acaagttcca aatagttttt atctcttaca
    25561 aaactagctg ctttatacaa tcttgaatga tatacccatt ggtctacaac tctaagtggt
    25621 ctttgtgcat tggctaaatg acatatagag tcttcagtaa gcactgccat atctaatgaa
    25681 tttataagct ctggcattcc atgatttatt tctgggtcta tatgatatgg tcttccacat
    25741 aacacaatcc ccttcatatt tctttctttt atttctttaa gtgctctttc acctgctgct
    25801 tgtatctcca ttttaaataa attctgttca tcagtagctt tatcaactgc atgattaact
    25861 tcttctttag ttatttttat atcagaaaaa tgtcttgata attcatcata tagtcttttc
    25921 ttcaattttt ccttatcatt tagacttata aatggattta tataatttat gttcttattt
    25981 cttatattct ctacattgtt ttttattact tcagaatatg atattacaac aggacaatta
    26041 taataattat ctgcatttga atcctcttta ttttcatttg ttacacttgg ataaaatata
    26101 ttttttatac cttttgcaat taaattttct atatgtccat gaactaattt tcctggataa
    26161 caaactgttt cagatgcaat actagttata ccagtttcat ataactgttt tgatgaccta
    26221 tctgaaagta caactctaaa gcccatagca ttgaaaaaag taaaccaaaa tggataatct
    26281 tcatacatat ttaatactct tggtatccct atttccccat tttttgcttc ttctttttcc
    26341 aatggtttgt atctaaaaat tctattgtat ttgtacttaa ataaatttat tggttttttc
    26401 ttttctaatc ctattttttt atcaccataa atagcttcac ccttctcaca tctattacct
    26461 gaaataaaaa tttcattatc agaaaattta tttattgtaa gaagacaatg atttgaacaa
    26521 cctttacatc tagttacact tgcttctagc ttgatattat tcaactctgc cttagataac
    26581 aaggatgttt tgtatccact ttcatatttt tctttagcta taagtgctga accaaaagct
    26641 cccataattc ctgaaatatt aggtctaatt acattttttc caattagttt ttcaaagctt
    26701 ctaagcacca aatcattata aaaggttcca ccttgtacaa caatattatt accaatctca
    26761 tttaaatctc taatctttat tactttaaat aaagcatttt ttattactga ataagatagc
    26821 cctgctgata tatctccaac acttgcacct tctttttgag cttgttttac tctagaattc
    26881 ataaatacag tacatcttga acctaaatct acaggatttt gagaataaat accttcgtgt
    26941 gcaaattctt ctattgtcat agataaagaa cttgcaaatg tctctaaaaa tgagccacaa
    27001 cctgatgaac aagcctcatt taatattata ttatcaatta ctccatcttt tatttttagg
    27061 cacttcatat cttgaccacc aatatcaagt ataaaatcta catctttatt gaaaaattta
    27121 gcagctttgt aatgtgctat agtctctatc tctccgttat cgattttaag agctttttta
    27181 ataagacctt ctccatatcc agttacagtt gaactcaata ttttaatatt ttttggtaat
    27241 atatcatata cttcatttat aactttaatg gttgttttta atggatttcc ttcattgcta
    27301 ttataataag aatatacaag tcttccatcc tcatcaataa gtgctgcttt agttgtagtt
    27361 gagcctgcat caattcctaa ataacaattg ctttttatta aatttatgtc cacataattt
    27421 attttttctt tttcatgtct tcttgaaaat tcttcatact catttttatc tttaaataaa
    27481 ggttctaata aatttacttc tccatcttca atattcttta tactatccaa tttttctatt
    27541 agagatttta gttgtatatt atcttcatct actgataata atcctgctcc aatagcaata
    27601 taaagttgtg cattttctgg gaagattatg ttttcatctt ttaaatctaa tactctttta
    27661 aatgcttctc taagttcaga taaaaagtac aatggaccac ccaaaaacgc aacatttcct
    27721 tctatttttc ttccacaaga aaggacactc acagtttgta cgacaactgc attgaaaata
    27781 ctcattgcta tatcagtctg attggctcca tcatttataa gaggttgaat atctgtttta
    27841 gcaaaaacac cacatcttga agctatggga tatataacat tatacccttt agcaagttca
    27901 tttaatccac tggcatctgt ctttaaaagt gatgccatct ggtctatgaa tgctccagtg
    27961 ccacctgcac atattccatt cattctttgg tctattcctc cacttagata tgttatcttt
    28021 gcatcttcac ccccaagttc tatgacaaca tcagtctcag gatgaaaata ctctattgat
    28081 tttgtactag atataacttc ctgaacaaat tttacaccta atttttttga tattccaatt
    28141 ccacctgaac cagttattat aatggtagta tttatatctc ccaatttttc atatatacca
    28201 tttagtactt ctttaactga tttttttaca tcagaataat gtcttctata ttctttatga
    28261 actatattat tactattatt aagtaccaca accttcaccg ttgtagaacc tacatcaatt
    28321 cctatatgaa ataattcatc cattgtaccc ctccatattt atatgctttt ttaatttttg
    28381 taagttctat ggctttattt taagtaagtt atttataatc tttatgacta atatttttat
    28441 tttatgattc ttttattaat caaagcttac tctactaggt aattcctaat tctaacctta
    28501 aattttaaat aagaacatat agttagtgta ctaaattttg tcataaattt ctacagattt
    28561 ttgttacttt ttacataaat ataacttaac tctaatatcc acttaatgtt tatgtattat
    28621 aaattatctt tagtcagaaa aaaatggttg ttgatatgta aattcttatt acatatcaac
    28681 aaccattttt ttgtatatta ttttttatct tagctgatta catttatcct acgagtgtaa
    28741 atataaagtg agcagctgct cctgcacata aaccacctat tgtatgagaa agaatagctt
    28801 tacctgccaa ctgtctagca tttaatgcat ccatcatacc aatatgtgta cttaaatatc
    28861 cactccaaca catacccata gctgtaaata ctgctatatc attaggagtt atagctcctg
    28921 actttataaa ctctggaact agagacattg ctgcaccaac agctcccaat gaagttatag
    28981 ggaatgctat tgcctctggt gatgtaaatc caaataatgg ttctaatata aatccaagtt
    29041 tatctccaat aactggaagt aattttattc cttcatatgc agctcctgta taaacttctt
    29101 gacctgtaac agggtctgta gatggtccaa aagttaataa catcaccaat gtacatacta
    29161 ctaggactcc aggaattata gccattccca tatctacccc cattttacca ccttcaagaa
    29221 ttgcatctaa agctctttga aatacatttc cttctctgat ttctctaaat tcatcctttt
    29281 tctctaatgt tcctgttgct ttatcttctt ccggattgta tttataaaac ttcttagtaa
    29341 atgtcaacat tattctaaca cttatgacac tacctataat tgcacctaaa ttaccaatta
    29401 atgctggaag tacatattct gtaccttgag aaatcataaa tgttgttaag ataagtccca
    29461 taccaaaggc tgttcctaag ttacataatg ctggaacttg gtattgttta aaatactgtg
    29521 tgaatgtttt atctttagca aaaggtataa tagctggatt atctgataaa taagttgtta
    29581 tagctcctgc tatactagca ccaggtagtc catataaagg cttcataaat acagcgaaaa
    29641 ttttattaat taacgctatt actccaaact ctgaaagtag tgcgcttaat gcgcctgcaa
    29701 gaactgccat agccataatt aagaaaactg tctccaatag taaagcatgt gctgtactca
    29761 ttattacttt gaacatcatt cctgctccca taatactacc aacataccca aaaccaacta
    29821 ctagtaatat taggaaaatg aaggtttcca tgcttactgc cttaacctgt ctcctgtctg
    29881 ttaacttctc cattttgaat catcccttct ttttttgtta taaagtttaa caaaaccttt
    29941 tctctttttt aattatactt ataagtatta ctatttgcaa ctttatttgt cattttttta
    30001 tcatttttaa aataaaaatc agtattttaa taataaaaat ttttcagatt tatgcaagtt
    30061 ttcgacatct tatctttcat tttataaaaa gtatgattcc ttactaaata tatatatact
    30121 tctctaacga cctaatatgc aaatataagt tgtaacttgt atctttttgc atgaaagaaa
    30181 aaagattatg aaaaaatttt tccttcaata tttttcataa tctttttttt agttttatat
    30241 aattttttta aaaaattttt ttaaaatttg ctttaagaaa tatatattat tttaattttt
    30301 cagctacata ttttactaag tcaacagttc ttgaagaata tccccattca ttatcatacc
    30361 aagaaactac cttaatcata ttgtcttcta taaccattgt ggatagagcg tctataatag
    30421 atgatcttga atctccttta taatctatag aaacaagtgg cttgtcacaa tatcctaaaa
    30481 caccttttaa ttctccttca gcagcatctt ttaacacaga gttaacttgc tcagatgtaa
    30541 cgttttcttt aagttcgcac actaaatcaa caagtgaaac tgttggtgtt ggtactctaa
    30601 gtgaaaaacc atttaatttt ccttctaatt gtggtagtac tcttgacaca gcttttgctg
    30661 ctcctgtagt ggtaggtatt atagattcag ccgctgctct tgctcttctc aaatctttat
    30721 ggcttttatc taatattctt tgatcgttag tatatgaatg tactgtagtc attaaccctt
    30781 ttactatacc aaatttttcg tccaatactt tagcaaaagg agctagacaa tttgtagtac
    30841 aagatgcatt tgaaattata ttgtgctttt cattatcata ttctttctca ttaactccga
    30901 taactatagt tatatcttca ttttttcctg gagctgttat aattactttt tttgctcctg
    30961 ctttaatatg cttttctgcc ttttctcttt gtgtaaataa tcctgttgat tctattacta
    31021 tatcaacccc cagttctttc catggtaatt cttctgggtc attatatctt aatattttta
    31081 tctctttaga gtttactact agagtgtctt catcctttgc ctctacttca cctctaaaag
    31141 ttccatagca tgaatcatat gtaaataaat gtgccaaaga ttctgttgtt gctcttgcat
    31201 ttatggctac aatttctata ttatctccta attcttcttg agctattctt aatacagctc
    31261 ttcctattct tccaaatccg ttcattccta ccttaatttt cattatgaaa tgtctccctc
    31321 cattactatg tttttacatg attattgtac actaaataaa tcatttgttc aatacttttt
    31381 cttgattaaa taatcaaatt ccatgttttt ttattatcaa aagacaatta gtatatcatt
    31441 tttctttatt ttacccctca tttagtatgt actttttagt gtaaagaagc tgaaatcatt
    31501 tattttactc aatgtccctt gggacatatt ttgccatctt ttttttgaat ttttaaacta
    31561 tactcatttt taaaaataat atatcttcaa gaatctcctc taatttaaaa taataaaaat
    31621 aaatttttat ttagttcaaa aaatatatga ttttttaaaa tttgctacaa ttattattta
    31681 tatatcaaaa tataaataat aattagctta ttgttaacta aattatggaa atatacttaa
    31741 ttgaaaactt aaatttattt ccttgtgtta tcaagatttc atgcttacca tttccaatat
    31801 catgctaacc aacttttgat gtgcataaac tatttcaagt aaaaatgcac aacctatcct
    31861 ttttgataag aaaaagcagt caatcataaa tatcaactgc ttttatgtac tgaatatcaa
    31921 gttatagaca atctggaatt tattttgagg gtttttcttt ctccttaact aaattgcttt
    31981 caaaagtaac ctttacaact gcatgattta ttttaattcc agtaaagcat atagcatact
    32041 ctttctcttt ttgtatatta gaaagagaaa ttgtgaatgt atcattatta acgcttccat
    32101 gccatgtatt actccataaa gtttcatctg ttttattgtc ctttatttcc acaataccac
    32161 tatctccatc cattttaaaa gaaatctctg tgtctaaaac atctatatca ttagacacac
    32221 aaaacaaacg tgcattaaca aatgggtctg aagtatcata atttttatct aagtccattt
    32281 caatggttgt ttgtccggat tctttgttgt ttaaattatt atatttactt tcaatgcttt
    32341 ttttacaagc tgtcaagcta accacactaa tgatactaat taaaataata actaattttt
    32401 tcatagaatt tatctccctt acaatttcta atttttaacc ctacaaacta tagtattaaa
    32461 ctaatctact attttgcatc aaatttttca atcattcggc ctttaccttt tctcatttta
    32521 attgcaaata tgttaaataa ttttggaatt ttaattattg tagtatctta aattggttta
    32581 taacatatta tgaaaattta agagtcaagt cacttattta aaaatacaca aaattatact
    32641 ttattgtata aaaaaagaga ttataattta tacaagtaaa ataaacttta ttattttact
    32701 cttctatata acctcttttc tatatatcta ttcaaataat ttagctccta aactcacaaa
    32761 catttgtaaa atcaaaaatg cttttgtgtc tatcttatga ttactttgta aaatctcttt
    32821 tgcatcttct tgcgaaatta aaagcgcttc aatctcttca tctggttcta aaaattcatc
    32881 tgttatatca ccatcacata tacaataaac aaatgcaaca gattcatcac tcattccagg
    32941 agataaataa actttatcaa tacttttatt ttttttaatt tctaaaagag taagtcctgt
    33001 ttcttctcta agttctcttt caacggaaat atctatagac tctccttcat caacaagacc
    33061 tgctggtaac tcgtatatat atccattaat aggtattcta aattgtctta ttaaaattaa
    33121 ttttttacta cttttatgaa gcccaactat tacaactgca tctacactat cttcttcatt
    33181 cttcaaataa atatttttta attgctcact actttttctt gatgctacca tccaaacctt
    33241 atcttcatct aatttgtttt tatactctat ttcaaaaagt cctataaact tattttcaat
    33301 cattggattt acattcttta ttatagtttt tttcaaattt actacgacct ttctttttta
    33361 ataccttttt aacatcatta agtaaatata atatcttaac aagtattcaa caacttatta
    33421 tatttccatt tcaggattat ctttatctac aaaacctact ttaatttcac aattaaatat
    33481 ttcctttaac aattttgcta attcttctct tgcactcatt accttatcta aattagcatc
    33541 agtaaaacca tctataggaa aaaatatatt ttttgagcta ttagtaattt ttccttcttc
    33601 tccttgtctc catatccatc ttctagtttt taccatgtct ccaactgaat aaattaattc
    33661 tccttcttcc attaattcaa catcagtttc tccaaatggt acaaatttat cccctttttt
    33721 agaaaatcta acatatacat catcatttct aaaatccata tcatgagcac ccattggaag
    33781 taaatatttt aaagaaatag agtttcctaa atctacaata ggatttatat gaggaagttt
    33841 cttattctta gcaacccttg ttgtcattgc ttctatcgaa ctcataaatt tatttgggtt
    33901 catgcctaga cttctaaatg cctctctata tggtataatt tcttctgatt cctttacttt
    33961 tttatctttg aagtaatctt ctactctatc tatacttata tctaaaaggt tgcttattct
    34021 ttctatttct ttagtattat ctattccttt tgcaactact acaccaaagc atacattttc
    34081 taatttatca aaaacttctt tttctactat aaatttcatt ttgctttatc ctcctgttat
    34141 tttacattat tttctaaata gattttatca ctttgtgtct tataaatata ccccctattt
    34201 gctaattgtt taattttttt aaattttcca attaatatta tatttattct tatcaaatat
    34261 tttatatgta ctaattacaa atttaacttt ccaaaacaaa tatattgttt tataatgtat
    34321 aatatatttt tatggaggca agactgtgaa aaattttatt ctaatatatt ttatagtgat
    34381 taattctatt gctttctttt caatgtacat agataagaaa agagcaatta gaaacgaatg
    34441 gagaataaaa gaagctactc ttatgtctat agcagtaatt ggaggtagta taggttctat
    34501 aattggaatg tattctttta gacataaaac taaacacatt aaatttacat ttggtatacc
    34561 atttatacta tttttacaat ttttattagt atatttttat attttaaagt aattgaaata
    34621 taaaacctta ttcttttcaa taaattaagg tgtataaaat taaaaatttt atacaccttt
    34681 ttctagcaat tattaaaaag atatttaatt aaaattaatg acccttatgt ttagcttttc
    34741 tcttttcttg tttcaaatta aatagtcttt ctttttcttc ttcttttcta tttttagcta
    34801 ggttttttct atcctgtttt ctttcttcat attgaagctt aagagcattt tgagccttag
    34861 tccctatagt ttctttttct tgttcctttt ttacttttct ctgcattctt ttgtatccaa
    34921 tgttgtcttt ggtcacattt ttttctaatt taatgctacc aaaatctaat gagaaaaatc
    34981 tttcaagtat aaattcatac acttctactt ctttaggttc tgctccaaaa actaccctac
    35041 atgcttcata ttttttacca tcttgtcttt caaatatacc tacccaaaat ggttcttcaa
    35101 ataagactgt taattttcca ctaattttgt ccattgctag ttcctcctta aattactttc
    35161 taaagaacgg acaaccaagg aggcaggtta ctgacagcta ttgctgcgtc tggactacca
    35221 accagactgt gtttttatct ttatagatta aatattatct tttttaatca tgcttgtcaa
    35281 tcttagtatc aacatctatc atattgattt aagtgaaatc aagtttttta actctacttt
    35341 attattgtta acactaagaa aattaattat ttttcataat aaattagtta ttatacttat
    35401 ttaaatatca atctttattg ttccctgcat aaacaagact gcttcaccag aaattttcac
    35461 agtattatcc ttcaacactt cacactgaat tataccacca cgattagaaa gttgagcagc
    35521 taccattttg tgttttccca acttttcaga ccaatatgga ataagattac aatgtgatga
    35581 accagtaaca gggtcttctg aatctaattc tggacaaaaa tatcttgata caaaatctgt
    35641 attacttcct tgtgctgtga ttattatacc taaccagtct gtcaatttac gcaattgtgc
    35701 gtaattaggt ttataattta taacttcttg ttcactgttt agcaataaga ttaaatctct
    35761 tgaagaataa acagcacttg gtacacagcc tatcaaatta gcttgttgtg gtgataactc
    35821 tatttcaata ggcattattt ctggaaatat catttcatat agatttccat ttcgtgtaac
    35881 ttcaagcttt ccactttgag taaagaaatc tatccttttt acattaacat caataaaatt
    35941 tgatattaca taagctgctg ctaaagttgc atgaccacat aaatcaattt ctgctttagg
    36001 agtaaaccat cgtaattcat aatttccttt acctttaact acaaatgctg tttctggtaa
    36061 attgttttct tctgctattt tctgcattaa ctctaaaggt attcttctgt caagaacaca
    36121 aactccagca ggatttcctt taaatagttt agttgcaaat gaatcaacta tgtagtattc
    36181 cattatttaa cctctctttc taacataaaa tatacatcaa tttacattca ataaaacttt
    36241 aaatttctta catatatttt ttaatattac tctgttcaac aactttttta cctaacaatg
    36301 taattgcttt tttgtcacaa ttatttacac aacgataaca cattgtacat tgcccatttg
    36361 caacaatcat acaattttta attactagat tcttcattgg acataaatta acacatttac
    36421 cacatacaat acattcctca gtattaattt ttagtttatc tgtacacata tttgttttat
    36481 tgataaaata caatcgttgt ccaaataacc ctacaatatg actcaaaaaa cccaaccctt
    36541 cttttggtgg tgacccatgt ttcagttttt tagcagcctt agttactttc ttttctgctt
    36601 ttattacaag ttttctatta tactctaaag aatgttttaa taccttttca tctcctatac
    36661 tatctggcat cttcacatgt aatccaccaa cagttatagc accgtatttt tttaatattc
    36721 tagataacac accagagcca tctccactaa atagagccat agttgcaata ataaaaacac
    36781 gtttaccatt ccacaaagtt gaatgattta ttataaaatc tttcaatatt tttggcacat
    36841 tactatattg cacaggataa ctaaaaataa tattctcatg attattgatg tgctgtaaaa
    36901 gttcattatc ttcaatagaa taagaatttg ctgttatatc atattcttgt aaaaattttt
    36961 ctacacagta tcttgaattt cctgttccac taaaatatat tcctatcata gtatttctcc
    37021 taatagctaa gattatatag ctctattctt aaaattctga ctttttatat tatctaaatt
    37081 aagtagttta tttaaataat ataaacttca ttcaacaagt tacctactga acctcccatg
    37141 actaaagtca taggattcct gattgataga attttgcata atcaaattac taaatacttg
    37201 tctaattctt tttttatcat tttaaatata cattttaata atattagtaa gctatacttc
    37261 cttaagcata tattttccct aaagtaaaac tattgatgat tattccatta tataacctaa
    37321 ttataaattt agtaagttca tcacatacta tacccttaat tctcaattat aaagtttcct
    37381 aaaaaatatt tgaaaattta actatgaaaa aatttcctat tgcctaatat gtataagtaa
    37441 ggagtactat atagtactcc ttatattgta ctcttataac attgatgcct taatattatt
    37501 ttaatcttaa tcattattga tttgatttaa aattataaac aagttccaat attttaatta
    37561 tgtcaactat atctcttata gttttaataa tctcatcaat tggtttatgt gcttgttgca
    37621 ctttatcaat agtattaatt aaatccattt acacatctag cacctgtatg gcaatttagc
    37681 attatcctta tcttatactt tgttgtaaat tcttgattac ataattctat tatctaactt
    37741 atagctgtgc aatctacatt atctgtaaat actttgcttt atatattttc cctgaacctc
    37801 taacattaat ataacagcct ttttgctata cacttttaac tacatactta attttaataa
    37861 cattacttgt ttataaaaat atactataga taaatttcac ataaaaataa taattcaagt
    37921 attgattttt atataagcaa atttgtaatg tactaaaaat aacataaaag tttccatttt
    37981 tcaatatgta agcttttatt atgttatttt attgttaaag gtttcaagtt tttatttatt
    38041 cattttaaaa aaaattatta tttttgtaaa actaatccca tagtcatact atcgtcagaa
    38101 tatgcttcac ccttaacatt actaaaaaac tcaacagact taaatccaat attttcaact
    38161 tctaataaga aactttcttt tgaaaaatag tgattccaaa cataaaatac attttcatct
    38221 ttttcggtta ttacaagagt ttgttctaat gtattataat cattgtattt acaattatct
    38281 tgtagacaca tatatttttc attactccaa aatcctccat cttcatttat ttcccaatat
    38341 ttaatttcct caaaattatt gtatttattt attgtaaata catctaatat taattttcct
    38401 ccaggtttta aactatcata aattttttcc attaataacc ttctattttc agttgacaaa
    38461 gctccataat cacaataaat taaagtagcc aaatcaaatt cctcattata gttcatattt
    38521 aaataacttt gaaacaagta atttacgttt aaattagtct ccttatttct attttgtgca
    38581 tagttaatag aacgttttga gaaatcaatt ccagttacct tataaccttt ttgtgcaaat
    38641 ttctctgcat ataaacctgg accacaacct aaatcaagta atttaggata attagctgga
    38701 tttgcaactg taactatcca atttacagaa tcctcgataa agttaaaatt tctacttgct
    38761 ccttcaaaat tagtgtctaa gtgtgctttt aataattgct ttgaaatata ctcatcatcc
    38821 caaaaattaa tttcactttg tttataaagc tctggtcttt ctaaatacat acataatttg
    38881 tttaacaaaa cataccactc cttaaaattt atttttaaaa taaaaaaacc acagagttta
    38941 ctctgtggtt taacttcaaa aagatgagtt taaataagag taaaatagaa ccaaatattt
    39001 ttaagcacaa caataaaact acagctttac tttgtttgct tattaaattt gattttattc
    39061 actcttttcc agcaatactt atatcaacga ttttatgata tcaaatatca ccgaacaaca
    39121 tcatcctttc atatttttat tttatgaatt aattatatat ttaaatttta tatttgtcaa
    39181 taaattttaa ttttaataaa ttttaatcat catagtaaaa aaaatttttt tatataaaac
    39241 taatcaaaaa aagatatctg tacatctcct gagtttttta acttttcctt cattatttta
    39301 gagtaactgc ttgatagaga atacttatat ctaagttcat taaccatttt atacaattga
    39361 tttttatact ccctattaag tgaacctgca ctatatagta ttgataattt atcaaataat
    39421 tcaggaaact cttttttaac aaagtcaaaa aaaacacctc tagttatacc ccttaagtat
    39481 aaagtcccag gtaaaacata atgtacatta cattcttttg catgtctaaa tagcgaattt
    39541 atattatcaa aatcatctgt aatatatggt ataattggca taatatgtag accaactgat
    39601 gcgttagttt ttctaaattc ttttaacatt ttaaatcgtc tcattgaatc cacaccattt
    39661 ggctcaataa gcctttgtgt atcttcattt actgtggtaa ttgtagatgc tacattgata
    39721 tatgtaatcc tagatagctt atcaattaaa tcgtaatctc ttaaaattaa atctgacttt
    39781 gtagaaataa tagctggtgt cttgtatttt attagcaggt ttaatatttc tggcataatt
    39841 ttatagtcag cttctattgg ttgataacta tctgtaactc ctcctatatt gattacttct
    39901 ttcttccatt tactgctttt aagttgtctc tcaagttttt ctactatatt tgtttttaca
    39961 taaatctctt caaaataatt attggagttg atgtacttat gagagtaaat agcataacaa
    40021 tatttacatc catgctcaca tccacgataa atatttaaat cccatttata tggcatactc
    40081 ctttttaatt tattacaagc tatttcacaa tttattggaa tatattttat tttattatac
    40141 aaataatcac ctctttatat acaataatac tataatgtta atctatagta attaaaacat
    40201 gatatttcca gaccacaatt cataatcttt actatattta caaagtaata tattccattc
    40261 atttattggt attcctccac atgttgcttt ttcttctaaa ttatataagc attgctttaa
    40321 atacatttta ttatgccaat catcatataa attttctaaa tttaaactat gttcattaga
    40381 tatatcattt gcaaaatttc tatttttcca ttttaatata cttgtatatt taagttcatt
    40441 aggtttataa tttcttttta acatttcatc atgtacaatt tttgtataaa atttaaattc
    40501 atctatacta taattcaata ctttattcac taatagatgg tttggagtac cttttttatc
    40561 tatagaacct tttatagcaa gtagctctct ccattgactt actaattgat ttttaggtaa
    40621 tacatcaatt aaatccttat gccataatct cataatttaa ctccttacta taaaatattt
    40681 tataaattca ataaccaatc tatcttacaa ttttacatgt tcaataattt tatctgtaaa
    40741 aactatacca tttaaatggt ctatctcatg acaaagacat tttgccataa aacctgaacc
    40801 tttaatttct attttctcac catattcgtt tagagcttgc actgtaactt tttttggtct
    40861 ttttaattta ccccatactt caggaaaact taaacatcct tcaacaacaa tttgttcccc
    40921 ttcttgttta ataatttcag gattaacaag cttaataagt ccttctccta aatctataac
    40981 aactaatcgc tttaatactc ctacttggca tgcagctaat cctcctccat ttggagtatt
    41041 gtacatagtc tctgccatgt catttaatat ttctcttatc ttattatcta cgttttctac
    41101 atacttactc ttttttctta aaatttcatc atcaaatgtt cttatctttc ttatagccat
    41161 aatattctcc cctacttatc tgtgctcttg attttctttc actttcttca aataaaaata
    41221 cactttcaat tggttcatta aaaattcttg aaatatcata tgccaaccat attgaaggtt
    41281 catttttacc agtttctata gcatttatag cctgtctaga tgttccaact aatcttccta
    41341 gttgttcttg tgtcaatcct aatttttctc ttaatatctt tattttattt ttcatatttg
    41401 ctccattcat gtaaggttaa ctttacatct taaatgtaac atttttcaac attactgtca
    41461 agtcaacctt acatttatat gttaaatttt cttatttaac tattttttta ctaaactttt
    41521 taaataataa taaaatccat attaatgata taacaattga aataaacata tagacataat
    41581 tatcttcctt aaatgccttc gatatccaaa aagttggtaa gaagaacaga atatattgtg
    41641 ctttatttaa aataaaaaat ggtgctaaaa tacccatcat aaaaacacct gagaatttcg
    41701 taattaccat tccttctagt ttatttgatg ataaagaaat cactaatatt gatataataa
    41761 ttccttgtaa taaaactaat aaagaaattg ataagtttaa caagagagaa attttagtta
    41821 gagaaaaaaa gataagtaga atcatagtaa taataaatgc taagatacct ggtattccaa
    41881 atcgtgaaat aagataacca gttttaccaa gcggagttac tattaaatat cttgaaatgc
    41941 tgtcatcaat ttctcccaat atgaccattg tagaagcaaa aaagaacata aaaggtgtaa
    42001 taaaagctaa aagtaaatca aacatcaaga aatacggctc taaatttaat tgataataaa
    42061 acttgttaag tgatatattc tgtattaatg gtattccaaa ttttataaat actccacata
    42121 atattggaga aacacatact ataaaaagca tagcatctct cttaatttgt ccaaactctt
    42181 gtttaaacgc atttataatc tttatcatag ttttactcca cctacctttt tccaactgct
    42241 acaaataaaa taataagtta taaaataaat tattattata attgatatta aaattaaaat
    42301 attaatcatt ataaaatttt tatctccact aataagagaa atacatatat taaaagggta
    42361 caaatttgca tatgattttg tgtcaagaag tacattcagt attggtggaa taaagcatat
    42421 aatctcaata ggaatactta aaacaataaa ctgattcaaa ctagatgctt tacttgcaac
    42481 tatcaatcca agcaaagaaa atataataga agaaaaaaag gtacctatag ttgatattat
    42541 aatattatct aaatttaatg taatagcaat aaacatagct acaatactag atattactcc
    42601 taatgaaatt acctttgata aaatatactc agatactttt actggagata cagctaagga
    42661 atttaaaacc ctttgacttt tctcaagaag tacaatagct cccataaaaa acaatcccat
    42721 tgctgctggg tcagaataaa tcataattat agctattttt tctctcataa aagttggaaa
    42781 tacattgata atacaaatat atataatact taaaaaaaga tataaaaaat aaaaaccata
    42841 cttaaattga aactttatat ctcctaaaat aagatttttt agcctcattg taaattcctc
    42901 cctgttatct caataaaaat atcatttaat gttggttcac tactatgtat tgataaaagt
    42961 ttatttttct caataagcat attcaaattt ttatcattag cagtattgtt cagaaaacat
    43021 tcagaagttt tttctccatt atcaaagtaa gtatatctaa ctttaatagc tccttttgac
    43081 ataataagat tatgtggtgt atctaaagca gatattttac catttacaat gaacgctact
    43141 ctgtcacaaa gctctgttgc atctagcatg ttatgagttg ttaaaataat agttttacct
    43201 ttcgattttt ctgataaaat tatatctttc ataaccttgc tatttgatgg gtcaagacca
    43261 cttgttggtt catctaaaaa taaaatatct ggattatgta ataaagcttt tataaaattt
    43321 aatcgagatt tcataccttt tgaatactca gatacccttt tatttgcttc attttctagt
    43381 cctactgatt ttaataactc atcaatagat agtagttttt tagaatatag agacccaaaa
    43441 tattttaaat tttctattgc agtcaacttt tcatataaac taggaaattc aaaatcaact
    43501 cctatatttt cataaaattt atttgagtgt cttttactct ctactccatt tacaatgaca
    43561 cttcctccat aattagttat cattccaatt agaatctttt gtagtgtaga ttttcctgca
    43621 cctgatggtc ctaaaaatcc tagtatttcc ccttttccta cttcaaagtt aatattttgt
    43681 aaaaaatctc tatctgtata actaaatgat aaatcatcaa ctttaatcat tcaatatcac
    43741 cctttcaaat ttttgactat tttgactata tggtcaataa aatataattt ttttgtttgt
    43801 taataatttt taataaaagt tattagcaaa caaaatttaa attctattcc ataagttgta
    43861 taactaatcc gtttatcatt aatctcaaag catcttcaaa acaattactt ccaacctcgc
    43921 gcttatatag catggtaaga aaaactgctc taaatgctcc actaaagctt tctatgtctt
    43981 tattttttgc atttggtatg caagatataa tctctccaat ttcaaagtca tcatgtctaa
    44041 agtgttcttc aattatagaa tctggtaact ttctcaccaa tatctcaaat tctccattta
    44101 tcatgagatt taaaattgaa gtactatcaa ccatcctata gaatttcata aatatatctg
    44161 tcaattgttc acatgtaata ctttcatcta ctctatttat ctcatataag atttcttttt
    44221 gtatagagtc atgtatatct cttaatacct caaaaaagag caattctttt gattgaaaaa
    44281 atagataaaa agttcctttt ggtattttta cccgttttac aagctcatca acagtagttt
    44341 ttctaatacc atattgctcc atacacaatc ttgcttcttc tttaagtctt tttattatat
    44401 actctctttc tttatcagaa tatgatttag gcatcttttc cctccagttt gactaaaata
    44461 atttatatag tcaatataat actttttcta tctaatgtca atagtattat tagtatattt
    44521 aaaaataagc ttaaaaactt tcgaaaattc tgaattttat atagcatttt ttattatcta
    44581 gtgttataat taagatataa ataatatatt attctaattt tcatatctat ttgcttattt
    44641 tttaacttag tttctaatag aagtaatcat atttatcttt ttaaaagttt caactttaat
    44701 aaaaaataaa ggagttgatt ttatggctac tactacaaaa aaccgttttt acgattatgt
    44761 tcaagaaaac ttaaataaat atgttgaagt acattcttac tttagcagtt gtcctctata
    44821 tggtgaaatt atagaagcag atagcttatc aattacactt tgctcaagat atatagatga
    44881 atctaatcca actttaaatg aaacttacac attatattta ccattaagtt caataatatc
    44941 tattagaaca ctataaaaag ttaattaaat atgggttatt tatatataaa atgtaagatt
    45001 ttctatattt ctatataaag taaccctttt ttatgttttt aaacttatac tacataaatt
    45061 taaagctgaa aataaaattt tacaatcatt gattatctta tttatcaata atttaaagta
    45121 attattttca gcttttatta agataagttg ctaatacaca ctaatatatg ttaatactta
    45181 agtactctat ttagcacttt ttaattttac taactcttta aatgcatttt tatttgctcc
    45241 tccaccaact tgagttactt tttctaaagt cttattttta agaacttctt tttggctatc
    45301 agctaattta tcaccaacta aaattactgg tgacccagtt tttgctccta aaggaccaac
    45361 tgccaatcca tctattaaat cattttgatt cttgattcca tttttaacta caaatgcatt
    45421 ttttaaagta tcttttttat aaaaattatc tattatcttt gaattagttt cgtctctact
    45481 actaccagat aatctagttg gattttttaa cttactttct agattgtttg atagggatgc
    45541 tgttcctcca ataatataag atttctctat atttaatgaa tttagaaatt catcagctcc
    45601 ttgcaattcg ctcttttcat ttgcaagtat gattggtatg ttattttctg ctgctgcagc
    45661 gcctacacta attgcatcag ctaatccttt cactccattt acaactgcta tttgagatac
    45721 attttttata ccatttaact tttgagctaa taataaactt gtcttgtatc tatcacttcc
    45781 tgatattctc tctatcgata tatttaagct ttttaattgt tgttcaattt ctttacttat
    45841 agaattttct ccgcctatta ggtatacttt cttagcacct aatctctgta tctcagcttt
    45901 agtttttgaa tttaaagctt ctttttgtgt caataatatt ggtgaattta tagcagatgt
    45961 aaaaggagtt gctgccaatg catctactat tgaactgcca tttactaaaa ctacattttc
    46021 tgaagaattg aaaccatttt gactaacttt gatagcagtt tcatatctat cactaccaat
    46081 taaagactca tttgggatac tctcaccaga agacttttct gtaacagctt ttatagtaaa
    46141 attacacgga tagaagttac tatctctatt tatatcaaag aattttccag tattatctat
    46201 gatataactt tcacctaaat tagcttttgc tttaaatgta tcatatcctg gtacatttga
    46261 ctcagaacct atagttgact ctccattttt cccctctata ctgactacaa ttgcaccctt
    46321 tccttctggt atatcaaaag aatcaattgg aactgttatg tatcctgaat attgggcagt
    46381 accttctttt aattttttca tattgttttc ttgaggtata ccatttacta ctggagcata
    46441 atatacttca tacttagctc ctatactttc agttaagaac attacagatt ttagagtttc
    46501 atcgcctcta ttgaaatcaa atacatttgc agctgttatc ttttttgaaa ttaaaggtac
    46561 aatacttgca tagtcatgtt gatacatctt ctcatcatca tttggttttt taccaccttt
    46621 gattgaaaaa ttatctatat cagacataag tgtcttgtct tcataagata tccagaaata
    46681 tccaccctca gaattataat ctccccagct attttttatt aaccaagcac cattttttga
    46741 tggtctaata tttgcattaa aattatcttt agaatagtta tcatcccaac ctacaattga
    46801 aatagcatga tttgtattaa aactttttgt tggacaataa tatgaatttt ggtcatcact
    46861 ttgatattta atatcttcat aataaccaga tgttacagct ccatactgta atatagcatt
    46921 ttttgtagaa tttatgtcat tgcttacaca cacagcatct gtcacattaa aaacagtagg
    46981 tgctgtattc atattagttg gtttttttgc tccttgtgct ttagatactc taccattgta
    47041 tgggatatct ttttctaatt taggacctga ccaagatgtt aaatatccca tagcttcata
    47101 atttaaagca ccattcatat catttacaga ccatccatat tcaccatctg aagcccacca
    47161 tcttaagtgt tcttctgata aatcatagtc tccataatta tttaacttta agaaactttc
    47221 taaggttgcc attgcagcaa aatcccaaca gattcctaaa tcctcttgat tttttattga
    47281 tgtcataaga cctaattttc tagggtcata agatgttgga actgttcttc ctttactttg
    47341 gatttgagta ccttccaact gatatggatt tggtataatc ccattatatt tttctgtacg
    47401 tccattttta gcatcattta gatattgttt atacgtctca ctgtattctg ctttttttat
    47461 ctgattcaat gtattgctat tgtcagctga tacaggaatt gttgacatta ctaaaataga
    47521 tattaaaaac agcgcaacaa accttgttac tttttttgaa gtaaattttt tcacgctttc
    47581 tcccccttat tttgagctaa tttttaaaat tataatgtta tatatgacta aatatcaagt
    47641 atttacaaat ataaaatcat ttaaatcaat tataccaaag ttttccttta taaaaaagaa
    47701 aataaaaaac tgaacttatg ataaaattca gcttctcatt ttctttttta tatgttttta
    47761 tctaaatcct attacagcag ctcctaaagc tcctactatt tgagtatctt ctgcaataaa
    47821 aattttttta cccagtattt cttctatcat ttttactaat tctttacttt ttgcaagccc
    47881 cccagtaaat gcaacttcat ctactacctc acctcttgct aacattgagg tggatttatt
    47941 tgcaatagat ttaagtatcc ctgctgctac ctctccagta gaaatgtttt gagctagaag
    48001 acttacaatt tcagactcag caaaaactgt acacatacta gatatattaa ctggttcata
    48061 tcctttagct aatgtatcta tactttcaat atcgcttcct aaaaggttag aagtaatctc
    48121 taaaaatcga ccagttcctg cagcacactt atcattcatt ataaagttaa atacatttcc
    48181 atctctatct aaatttataa ctttactatc ttgaccacct acatctaaaa tagtccttat
    48241 gttcttgttt aaaaagtaaa tacctctagt atgacaagtt atttctgtta ctttcttatc
    48301 agcaaaatcc attactcccc ttccataacc tgtacctacc acctttttta tatctttttt
    48361 gtcaatttca ctacttagca actcatagac ctgtttagat gtacttttag ggctccatcc
    48421 agttggtata attattttct taataatttt ttcaccatca aatagcacac cctttgttgc
    48481 cactgaccct gagtcaactc ctatactaaa catagttcct cctactttta tttattccta
    48541 caacatctct acaaacgctt caaatctagt tcttaattgt tcagtatctg attttgaata
    48601 atcagtttca agagacataa atggcttatt tttttctttt gtaacaaatt ctcttattct
    48661 ataactttct atattaaatg tatgacatgc ttgtaaaact acatctatta cagcatctac
    48721 attatattca tctattattc tatctaataa ttcaatacga ttgtcattat tcatcataca
    48781 agaacaacct atatttatat atttttgtgt taaagcatca tatacatctt ctatttcttc
    48841 atcaaccaat aaatcgtttg atctaatagc tccacaaagt tcatatgcaa cgactgatgc
    48901 ccctgcatct tctaaagttt taactatttt ttcgcttatt ccaccaatag gagaacctgt
    48961 tatcaatatt cttggcttat ctttttgaac aggacattca cctttttcat atctttcttt
    49021 catatcatct ataacttctc ttaaagaatg tttaagttct gcacggtcaa atttaaaacc
    49081 tgcttgatat aaaacattat gtaactcaag gcctgtaagt gcagatggtt gtaatttacc
    49141 aagtgcataa aactctttta aaagttctct ttcttcattt ttatctttta tagcagttct
    49201 tatatcttct tcagttatag ttacacctaa agatttctca accccttctt ttaatcttat
    49261 catttcatct ttccaaagtt tataggcaaa ttctcctttt gaagtatttg gcaaatgcat
    49321 tacatatgtt ggcttaactt ttgcaagttc ttcatacatt tttttcttac catcacaagt
    49381 ggtttctcct atcaacaaat cagaaaaata gaaataagga caggtatctg ttattgcatg
    49441 tccatagctt gatttaatta aaggacaaag atttcttgga agcacccttt ctgcatcagg
    49501 tattggctct tcactaacac cgcatacacc tactacagtt gctccagctg ccattggaat
    49561 ttcaactgga gtaaatgtac agaaaactcc aaccatcttt ttaccacttt ccttaagttc
    49621 ctttgcattt ataaatcctt tttgtctagc ttcattgaag ctatcaaatt gttttggcaa
    49681 atttgtcatg aaaatattcc tcccaattac ttctcttcat aattcaatct attcgtaatt
    49741 caatttgtat cttaagcaat aaaaactaaa tttttccatt aaaatacaaa cctctacatt
    49801 agattctatc atgctttacc ttttatccat aattgttttt atcaatgcaa aattagatac
    49861 atatagatat attgtataac taatttttta tgttataatt tttcttataa cttaagctct
    49921 cgaatcctca atctataagc agacacagca gtttcacata atttatcaat taattttcca
    49981 ttcacataaa atcctacaaa tgctcctatt ccaggcatta gttgtaaaaa cttagctaaa
    50041 tctaaataat ctctatactc ttgttgaaat gttctccaat caaaatcatt gatgtcttct
    50101 ggtagactat ttacatattc atcccagtta ttcatcaatt taaaagtttt gtttatatgc
    50161 tgttgactag aaaaagccaa ctgtaatatg tttaatatat aaatcctttc tctataatct
    50221 ttaacatcat atccatatat tgaagctaca tcatataaaa atttcacttt aatacctaaa
    50281 agcaaaggaa aatcagataa acctaagagg attcctcctg cccctgttcc tgccccttca
    50341 atcattgctg tagtcttgta agttttagct ttttctaaaa ctaatttttc tctttcttct
    50401 aatgacatat ttctaagtgg tggctttgta gcatatttat atccaaacag tacggttttt
    50461 gtcattactt ttatagaaga agtaattatt tcatgatatt tatctggcaa tactccatta
    50521 aatttattct gtataccctt tgatgctttg tcaaatatag aaggtttctt taatatattt
    50581 ttcttccatt cttcaagttc ttttttgact agtttaatat aaacaacatc ttcataatct
    50641 ttcacatttt ttctcctaat acaatgtatt tttgtcaatt taatagctta atttaaagtt
    50701 taaatatttt tatctattaa attaaactat tcaaatactc tttagtttct ttatctgcaa
    50761 aactagcttc tactgtattt ctataaatta ttttatagtc ttctaatcct agtttaaaag
    50821 tatcaaatat aacatttagt tctgaactta aatttatatc tgatacagtt ctattatcag
    50881 tatttatact tacatgtaaa ttatctttat aaaaagtata aaatggatgt gcttcataag
    50941 aatctactgt cttagtttgt acattactag ttggacataa ttcaagcaat atttttttat
    51001 ctttaactaa attatacgcc tttttatggt ctttaatttt tacaccatga ccaatcctat
    51061 ccgcctttaa aatatttata gcatctaata cattttctcc acttgcagct tctcctgcat
    51121 gtattgtaac tttatatcca tattctcttg ctaatttaaa aacatcttta tattccttac
    51181 aaaatccctc tttctctgga ccacacaagt ctactgctac aacaccttta tttacaaatg
    51241 attttccttc ttcaattact aataatgcct cttttgaggt cattgttctc atacaaccta
    51301 atattaaatt gccttttata tcataaatac tttcagcttc tctaattcct tcaattatac
    51361 cctcaattat atttttaaca ctcatacctt tttgggtgtg aagtaatggt gcaaatctaa
    51421 tttcaatata ttttacattt tctctacttg catcttccaa aagttcaaaa gtaattcttt
    51481 ttaaattttc cttagattgc attactttta agggtaaatc aaatttttct aaatattcat
    51541 ctagtgaagt acaattaaaa gaaacctttg ctaatttttt tatttcatcc atattatttg
    51601 aaggtaaatc tattttctct ttaatagcta tatcaagcat ggtttctact ctaacacttc
    51661 catctaagtg gcaatgtaaa tctatcttag gtaaattttc aaacatttta tcctcctact
    51721 gtacttataa ataatactat caacagattt ttaagtctta tttctattat atcaatatac
    51781 tacggttttt aattctaaaa aagtcacatc tcattaaaat attttaattt aatttatgat
    51841 tatctaatta tatctactga ttctttttaa tatacattta ttaatataca tttgataata
    51901 aaatttcaat acataagaat ttaagttata taattaaaac tttgaattac aaaggaggac
    51961 ttattttgat taccttaagt tttgatatag tgcaaacctt gacactatct atattcttct
    52021 ttttaattgg taatttattg aagaataaag ttaacttttt aaacgatttc tgtatacctg
    52081 caccagtaat aggaggtcta ttattttgtt ttctaaattt attttttaaa tattttaata
    52141 tagcagatat atctataagt ggaaatttaa tgccaaattt tataaccttc ttttttacaa
    52201 ctataggact tgaaataagc ataaatctta taaagaaagg gggtagtgta ttatttagat
    52261 attggatttt gtgtggagta ttagcatttt gtcaaaatat attagctatt acaatatcaa
    52321 agattataaa gcttgaacct cttttagggc ttatgtgtgg aaatgtatct atggaaggtg
    52381 gtcatggtta ttctgctgca tttggactta caatagaaaa tctcggtata gaaggagcag
    52441 ttggggttgg attatctgct gcaacaatag gacttattat gggtggtata ttgggatgtc
    52501 ctgtagctaa atttctaata aataaatata aattaaaacc atcatcaaat atggacttgt
    52561 caattcctag atataataga aatctaaaga tatttggaag taaatttttt agaaataaga
    52621 ataggataaa aaataataac ttctcccaaa caataacacc atctgtgttt ttggaacagg
    52681 ttcttctcat atttatttgt ataaatacag gagaaattat aagtagatgc ttctatataa
    52741 cgtttaatat actattaccc tctgttgtaa cttgtatgtt ttcggctgtt atttttagaa
    52801 atttaaatga taagataaat atactagaat taaattttaa acttatagat tttttaaaag
    52861 aactttcatt gggaattttt ttaactttat cacttatgaa tatagattta tttgaattat
    52921 ctacattatt acctcctatt ctcttaatag taacttttca agtaatcttt ataatcctat
    52981 tttcaatatt tatttgcttt agagtacttg gaaaagattt tgattctgcc atcataataa
    53041 gtggtttgat tggacatgga ataggagcta ctccgaacgc tttggcaaat atgagttctt
    53101 tgacacaaaa atatggtaat tctccaaaag cctttttggt tgtaccatta gtaagtggtt
    53161 ttttgctaga tgctattagt atcccatgta tactattttt tataaacata ctaacttagt
    53221 atgtttattt tttgttatat attgacaatt tactcttttt gttatatatt ataaatataa
    53281 agtttgataa tgattttcat taggaggtgt taataatgac tgtttacaac ttaaaacttg
    53341 gacaaaaggg aattatagac aatatagctg gaaatgaaaa acttatgaag agacttctag
    53401 ccttaggact aatagatggc actgaagttg aagtgaaaaa gatagctcct cttaatgacc
    53461 ctatagtgat tagatttaga gggtttgact tagctattag aaaatctgat gcaaaaaata
    53521 taaatttaaa aaataattaa tatataataa aaaagagatt ttaaaatcta ttttcaggcc
    53581 atcaacattc tatgtgttga tggcttttta aattcaatca tgttgtaata cagataatca
    53641 acagttagat aatgtacagt ataaaaaatt tatattaatt tgtgtagata tagttatgtt
    53701 attgactcat atttacttta atgggcagtt caaacaaacg atagaactgt ataagcaagc
    53761 atttaatgct actgttaaaa cattgattga agattcaggt catttgctta ttgttcataa
    53821 tgaaatagtc attcataata agttcttaat tttaaacgat tttggaaaca aaaatggtgt
    53881 ttcaatatca gaagggtatc aaccaacata taaaattcaa acggcttctt gattttatta
    53941 aatcaaaaag ccataagtca acaatctaaa aagagatttt aaaatctctt ttttttgttt
    54001 atgtatagat aaaattgaat aagtatttaa acattatata ctatgtaaaa gttatcaata
    54061 tagacttgta aataatagtt ataaaa
//
LOCUS       DAEORM030000024        53911 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.024, whole genome shotgun sequence.
ACCESSION   DAEORM030000024 DAEORM030000000
VERSION     DAEORM030000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 53911)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 53911)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 53911)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..53911
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.024"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            complement(7..1275)
                     /locus_tag="KRH23_001890"
     CDS             complement(7..1275)
                     /locus_tag="KRH23_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HHS5225170.1"
                     /translation="MSKNIYVKETYEWIRVGNGENELTEIEYEKLLKYLENNNDVLKS
                     NIIDIKYKKLRFINYVGIICFENVILEILPKLSLSDNLVKDREILLQMLSICNKIPIT
                     MNEKIRLSLKNYNLLNFFVMYFIESMQTQMKKGIYFEYINKIENLNVMRGKILLSTYA
                     KEKGISPMKIRCEYDEYSENNFLNQVLKKACISILCRINDNSIQGKIKKILSYFQNVD
                     LIYIDRKKLLDYKFYKNNDRFKDCYLLARLLLLNLSMDNSQNNQEAFSILFEINTLYE
                     EYIGILIKSIWDNSFRETYIQDKSKFLLKNEQTGKKNFNLRPDIVLYDLKNEYEIIID
                     TKWKAIEVDSNVFYRSSDIYQMYAYITAYENAKRCILLYPCIQKDKNYSSWKLSESFK
                     GKFIEAKTVRLDDIKNTKNDLKKIIFNYKF"
     gene            complement(1268..3202)
                     /locus_tag="KRH23_001891"
     CDS             complement(1268..3202)
                     /locus_tag="KRH23_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrB family protein"
                     /protein_id="HHS5225171.1"
                     /translation="MSENIRGTEYWLMEEFFYQETDTPQIFREESIIALGFDIKINLK
                     KVFSMGKKSEKYINENCNDKDFIKKFMSIKKGDYFLYKAYQNIEEKVKCNVSIGIVEE
                     DFENGYELSHILGHTLPVKWMHNFDTVSNCKVYTSEFYKLNNNDISSYLEIIKSQDKK
                     LLRKRIEESENNKWYLKNYYYKNVDKCVDDEELFIQPINLEQLESLKNIKTDDYILLY
                     NSEKVICENDHTMKSLFGVCQVMEGFDKEKVSALEGGYFFPVRWIEYEKENIDGNAWV
                     IFENNSIVEKYVKRFTNKMPLNTILYGPPGTGKTYNTKQMVYNLVSETSLRNRYYTGY
                     LDYKNNVEFCTFHQSYGYEEFIEGLKSDGEGNFKPEDGILKDISIEACYNALKFEKKM
                     SFELEKDSLTLETIKDRKKKLVLENIEYSESFNFEESENYVLIIDEINRGNVSKIFGE
                     LITLLEDDKRLTKSNQTIVKLPYSKEKFSLPPNLYIVGTMNTSDKSIALLDIALRRRF
                     NFEEIMPDYDLLSIVDGIDIRKMLYTINKRIEFLYDRDHVIGQAYLLAVENINDIVVV
                     FRSKIIPLLQEYFYYDSEKVGLILGGIGRNEKDKYIVYKEKLIASELFKNNNASIMES
                     KVNYCIKQNISSEELKNIYE"
     gene            complement(3231..3953)
                     /locus_tag="KRH23_001892"
     CDS             complement(3231..3953)
                     /locus_tag="KRH23_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein"
                     /protein_id="HHS5225172.1"
                     /translation="MENFNKNAKIIGIGAEGINIINEVEEKIKANMDIEKININQEIE
                     KEYVRSLLDGVDILFLIYSSEDKHIRDIIKAVSYMSNERRVLSIGMDCSEKENKEDLE
                     LGREFKINNDSIFKFVDLMNIMVESISDSCMINIDITDLKEATVGDKGIKYSFEEFED
                     TKSYSEIADILFDRMEYIGEEFISKKGIVFVEGSPEFSIMELNDLISNIQSKVEESYE
                     VIFSLYIKENLNGNIRVGLLYN"
     gene            complement(4003..4989)
                     /locus_tag="KRH23_001893"
     CDS             complement(4003..4989)
                     /locus_tag="KRH23_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HHS5225173.1"
                     /translation="MSKVKRLTDVWIYINDKQKFTIKELSEEFNLSAKTIQRYLKELN
                     KMGLPIQAEQGRNGGYRVLNNSYIPPVIFTEKEVMIILFALKSLQIYNYKLMEIEINS
                     IMRKVSYERKSSIKVGIENIKRYIGFVANDTNDGDFKSSNVTEFFRASSESLILNIKY
                     KCGNQILEKNVCPIGIYLNKGAWFSPAYDCKSDKIILVHIDNIIDIKRTGESKKIHIN
                     LEEWLHEVYNNLYGNSSTTKKFGEIIYLNVLLTKEGVSKIKDSSWNLDMELNEDGSGI
                     ISTFIKVEDIDCYASILFFIGNNAKVIEPKFLNKLLYDKANELRYFYEENMV"
     gene            complement(5046..5546)
                     /locus_tag="KRH23_001894"
     CDS             complement(5046..5546)
                     /locus_tag="KRH23_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HHS5225174.1"
                     /translation="MRKNSINIALTAAITAIYAVLTLSLGFISYGPIQFRVAEIMMLL
                     AFLDKGYIVGLTLGCFLANVIGPYGVPDIIFGTLATFISASMIYITRKLGKQNKSTLV
                     IASLWPTVINSIVVGLMLNVFFGLPLILSMIQVGFGEFVVVTIVGVPFFCFLMKKYKN
                     VINIKF"
     gene            complement(5832..6143)
                     /locus_tag="KRH23_001895"
     CDS             complement(5832..6143)
                     /locus_tag="KRH23_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5225175.1"
                     /translation="MAGNLNNMRAVNNFRGDKNILECLVSFEGRSISQRKVRVFFKEK
                     QNQIEIDFAEEEISKLVENVVLNTSYQEMLYDEIEKQLEIDCIGTWMILSKLKDGSRV
                     H"
     gene            complement(6283..8547)
                     /locus_tag="KRH23_001896"
     CDS             complement(6283..8547)
                     /locus_tag="KRH23_001896"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043546 - molybdopterin cofactor binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine dehydrogenase family protein
                     molybdopterin-binding subunit"
                     /protein_id="HHS5225176.1"
                     /translation="MNIVGKGIKKIDGMSITTGKPVYTDDLSAKDALVVKILRSPHAY
                     AKIKDIDTSKAEMVDGVECVLTYKDVPKSQFTLAGQTYPEPSPYDRLILEDVVRYVGD
                     EVAIVAAIDEKTAIKAMNLIKVKYEVLTPVLDFEEAIGNKTMVHDEDRHCNFDIGMQR
                     EKNIVSHHDYTKGDVEKVLSNCDVVIEETYYTQAQAHAMMETYRAYNYLDHMGRLVVV
                     SSTQIPFHVKRHLSRALEIPASKIRVIKPRIGGGFGGKQTACVEIFSAIVTLKTGKPA
                     KIIYDRKETFNCSTSRHAMRLKVRLGATNDGIIKAIDIKALSDTGAYGEHASTTIGLV
                     GEKTLPMYNKVEATRFIADVVYTNKMPAGALRGYGASQGCFAVESTINMLANKLKIDP
                     TDLRLKNVVTEGETTFAYGKTLNSVDLIKCINKGKELIGWNEKYPCKHFDNGKIRSVG
                     MAITMQGSGIQGLDKSSAEIKLNDCGDYTLMIGSTDMGTGSDTILAQMAAEVLDTSIE
                     NITVISADTDLVPYDPGSYASSTTYVTGMAVVKAAQDLREKIISAGATKLGVDKDEVE
                     FDGIKLTSKKGSTLLFDIAVDSTIGPDTNQLIGLASHGSPVSPPPFIAGFAETEIDTE
                     TGKVDLVNYVAVVDCGTVINKNLAKIQVEGGIVQGIGMALFEEVRYTEKGSMDTNTFM
                     QYKIPARCDIGNVKVDFVETYEPTGPFGAKSVGEVVINTPLPAIQEAVFNGIGVRINT
                     LPITPEKVFMEMNK"
     gene            complement(8551..9000)
                     /locus_tag="KRH23_001897"
     CDS             complement(8551..9000)
                     /locus_tag="KRH23_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="(2Fe-2S)-binding protein"
                     /protein_id="HHS5225177.1"
                     /translation="MLVKININGKKKSVDIEPEEYLVDTLRKVGNLSVKRGCDTGCCG
                     LCTVLIDKKPTLSCATLTLRALDKEITTIEGLENEVKEFSEVLVKEGAEQCGFCSPGF
                     ILTVLAMKDELENPTDDEIKHYLTGNLCRCTGYMGQLRAIKTYLEVK"
     gene            complement(9000..9788)
                     /locus_tag="KRH23_001898"
     CDS             complement(9000..9788)
                     /locus_tag="KRH23_001898"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1990204 - oxidoreductase complex
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD binding domain-containing protein"
                     /protein_id="HHS5225178.1"
                     /translation="MFTVMDIVQPDTVEEAYSILNKRKTNQVIGGSAFLRMGKKRIGT
                     GIELSKLNLDYIKEYEDYVEIGSMTTFRTLETSSIIKNNFGRIIEDSVKNIIGVQFRN
                     VVTVGATVFSKYGFSDLIVALLSLDTEVELYNIGRISLEEFLNRDYEKDLLIKIYIKK
                     TNKNASYKSLRNAKSDYPILNVSVSKHMEQFKLCVGARPQKATIAKQASEFLSNNEIN
                     EINIDKAVEIASEELTFGSNMRASREYRKAMSKVLLKRAIMEVI"
     gene            complement(9983..11251)
                     /locus_tag="KRH23_001899"
     CDS             complement(9983..11251)
                     /locus_tag="KRH23_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HHS5225179.1"
                     /translation="MEASIHTIASNNLLIIFAIVSITGIICSKLSEIIKVPDVVLYLL
                     VGILIGPSFLKFIDIRGFQIENQLILTFGSAFILYLGGKEISLKVLRNVKISVFLLAT
                     LGVVISAFIMQQVIGFTFGISAMTALLAGTIIASTDPATLVPIFNQVKIKDRVKQTVI
                     SESAFNDATGAILTSAVLAVILSNKFSLGENIYELGTMVIVGVLVGLITGILLLKLVN
                     DKPYGIFKDFAPIISVISVVVAYELSTKLGGSGYMSCFIVGIITGNKKNFKIWLSQKS
                     YDADFYVAETLGTICRMAIFIILGSQVNLAQLSKYFMPSVITVLVLMFIARPLCVLVC
                     TLVDREAKWSKSEILFMMWVRETGVIPAALCGIISAMKVPGYEVISSVVFMTILITLV
                     IQGSTTKLVAKKLGLLEEEVINISEKVSTF"
     gene            complement(11592..11753)
                     /locus_tag="KRH23_001900"
     CDS             complement(11592..11753)
                     /locus_tag="KRH23_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III"
                     /protein_id="HHS5225180.1"
                     /translation="MKQDKQNEKQSEISKIKQSNDNKLEIAQELHVSKNIGNMLGYRI
                     DKKKMNRPS"
     gene            complement(11902..12984)
                     /locus_tag="KRH23_001901"
     CDS             complement(11902..12984)
                     /locus_tag="KRH23_001901"
                     /EC_number="2.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lysylphosphatidylglycerol synthase transmembrane
                     domain-containing protein"
                     /protein_id="HHS5225181.1"
                     /translation="MRKLSKREKDFIQYGFLLFLICITTYLVLTTLDIKLIPKIIRLV
                     NKTYIFLGILTIIVYMIIESIVTHLIINAVQKTKVKFIGIKMATMGFYYNLVTPFASG
                     SQPMQIYALTKYDVSLSKSVAIVTNKTVVFQSTVTVFCGILILLNKSLLMEQVHSVKV
                     LITFGMIMNVSMLLGGLLIVFSPKQVKMIAEVLINFLSKFKTFKFLDSKRDRINHYID
                     DYNYSIKIFIKNVRILVLSILLTVLQLIAYFSIVYCVYKASNLRGVSYVHIMTLQVFL
                     YMAISPIPTPGNVGANEVTFFTMFSNIIPKELLGYSVLLYSGFVYYFILIVSGLFTFG
                     THYTLNSWKKEDKVNSNLDKVIEKLN"
     gene            complement(13087..14682)
                     /locus_tag="KRH23_001902"
     CDS             complement(13087..14682)
                     /locus_tag="KRH23_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative ABC transporter permease subunit"
                     /protein_id="HHS5225182.1"
                     /translation="MSNLSILIKNNIINEFKLNALKKADGREKQKIMGMMLSVVIIAG
                     LLIFYVTSLSLSLVDILKQINQLEMLLIFGFGLSTLTTIVTSLYKTSSYLFQAKDLDL
                     LTSLPIKESTVLASKILMLVGANYLFSSICMIIPAVVYFLNSDVSITYFPYLILLFLA
                     LPLLPIVASSIIFLFIGQISSRIKYKNLVLIIGSIILMLLYTLLMSRLNSMSVEMLKN
                     SVSISETIRKVYPPIYYFVDALKTGSIVSFLAFIAISIIPFFMFVTLFAKKFKDINAK
                     MSEGYKSKNYEFKGQKTSRPSKALLKKEFKRYTSSFIYFLNSSAGLLFLIVGTILILL
                     FGADKVGELLKLNIDFNLIKIQLLGVFFFIIVMNCTTYCSISLEGKNLWILKSSPIDE
                     REIFWSKVLMNFLLNAPLSILCLILVSIRLDFEIQFIIVSICLIVSFSMFVALMGLLS
                     NLLYPNLDWKNEVAVVKRSASMIVTMLVSLAYVIILGGIYVLLGISFLNVYIILASIL
                     TLILDFMIWRIISTKGVKIFKNL"
     gene            complement(14729..15436)
                     /locus_tag="KRH23_001903"
     CDS             complement(14729..15436)
                     /locus_tag="KRH23_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHS5225183.1"
                     /translation="MLKVINVSKSYKNKKVVSSVSFDVNDGELFGFIGHNGAGKTTTI
                     KAIVGIHDFEEGEVLINSKSIKKQPVECKKEMAYIPDNPDLYESLTGIQYLNFIADIF
                     EVAKDKREELIKYYSNKFELNKALGDLISSYSHGMKQKLAIISALIHSPKILILDEPF
                     VGLDPKASFILKEIMREFCDKGGCIFFSTHVLEVAEKICDKIAIIKDGNIIAYGTTEE
                     VKGSNSLESIFMELIEK"
     gene            15689..16834
                     /locus_tag="KRH23_001904"
     CDS             15689..16834
                     /locus_tag="KRH23_001904"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HHS5225184.1"
                     /translation="MNTFEQLKISSTLIDGLKKQDITSPTEVQSLVIGNIIQNKDLLI
                     NSQTGTGKTLAYLLPIFEKIDTSKRETQALILAPTHELVMQITNQVELLAKNAELSVT
                     SLALIGEVNIQKQIKNIKAVKPHIVIGSCGRVLDLIKQKKLKSHNIKTIVLDEVDNLL
                     NGKNITCIEDIIRTTLRDRQIIGCSASLTDSTIKICDKLMKEFEIIKTKEKSQINPNI
                     NHSYLLGEIRDKFTFLRKALAATNPKKAIVFVNNEKNIEVLVSKLNYHNYKAIGIFGN
                     MEKEDRKNAINKFKLGKAKILITTDLSARGLDIVDVSHVFNLDFPKSKNEYLHRCGRT
                     ARGNRSGNTISIITKKELDIIKDLQKEFNIVITPKTLQNGELIDIIK"
     gene            complement(16948..18324)
                     /locus_tag="KRH23_001905"
     CDS             complement(16948..18324)
                     /locus_tag="KRH23_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015851 - nucleobase transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HHS5225185.1"
                     /translation="MQTTNSSTMQKLFPILTNKNVDMKKEIIAGVTTFLTMAYIIAVN
                     PNILSETGMPAGALVTGTCLAAAFGCILMGVVANLPFALASGMGLNAFFAYTVVLQMG
                     VPWEVALTAVFVEGIIFIVLSVSGVREAVVNAIPKNMKLAVTGGIGIFIALIGLVNSG
                     IVIGDQATLIKMGRFTPAVIITCVGLIIIAVLDKKRVKGSILFGIVVSSLLAWAFAFI
                     NPEYAQKLGIYLPGGLFKFESLAPIAGKIDLGYVLHPTNIGGFLVVVCTFLFVDFFDT
                     VGTLVGVCSKANMLDEKGNVPNVGRALLTDAVATTVGAGLGVSTVTTYVESSTGVIAG
                     GRTGWTAITVGILFLAAMFFSPVFIAIPSCATAPALIYVGYLMLGTVKDIEFDNITEG
                     VPAFVTIACMALTYSIGDGLTLGILTYVFVNIFYNIFGAKKAEDKKHVSVVMIVLAIL
                     FIIKLWLL"
     regulatory      complement(18418..18520)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            18770..20116
                     /locus_tag="KRH23_001906"
     CDS             18770..20116
                     /locus_tag="KRH23_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HHS5225186.1"
                     /translation="MKDLTTGHEGKSIFFFAMPMLIGSLFQQLYNTADSIIVGRFIGK
                     EAMAAVSGANPIMFLLVAALMGVSLGFSILVSQFYGSGDLKKVKATIDTTYILLFIGS
                     ILISILGIVFGGPMLKLMNTPESVFAQSKLYLTIIFSGILFSAGYNSVSAILRGLGDS
                     VTPLYFLIIATILNIVLDLTFIVVLRMGVEGVALATIMAQAVSFIISIIYLNKKHEVL
                     KFKIKGIVYDNKIFKDGLRLGLPSGVQQMLFSIGNMALQFLVNSYGTSAMAAFGAGLR
                     IENFISLPIMNLGSAVSTFVAQNIGAGENERVKKGIRESIKMTLVLAVTVIALILLFR
                     ENLIALFNTDKDVIKIGSSYLFIIGPFFLFIGTSFVLSSAMKGAGDSMFALISSIVSL
                     WLGRLPASYMLSKFFGTDGIWMGIPFGWTLGLIVTVIYYKKGHWKTKAIVNHRINE"
     gene            20194..21588
                     /locus_tag="KRH23_001907"
     CDS             20194..21588
                     /locus_tag="KRH23_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0006811 - monoatomic ion transport
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HHS5225187.1"
                     /translation="MGIILKPKQFYMTVIATIILYFSLNYSFNIKFSICLSFLTILIW
                     AVDSVEKTFVALFFVILAFIFNIAPIKVILQFLFTENFYIIILAYIITNAVTKTGVAK
                     IISEKLILNTVNTPKKMILLSYILGILLIFFIPQPFPRVILVSAFYKEFLKEQQITED
                     SKSILLFSIFTASTFTSMFFVNGDTLLNYVVLELGNCNINWGQWAFYMSVPTIITCFI
                     TYFLFIFVFKKELHSIKFISNENLEGNKLHFSYSNLKKEFNLLNKEQKHVFLCLGIMF
                     FMFLTQFIHNINTLIIMSICVLLLLLRKIVGFSTLKEINWKVLIFFIAAFSIGGVLKY
                     SGVVDIMGNYLIKFIPNSSEIISILFLITLTIILNICLGSAVTTSSVVIPLLGSLHIL
                     KENSVTLCLFVYIIVSIQYILPFHHATIMVGHGENLYNSKVIFKYGLTLIPLTYFIII
                     CITFPWWKFIGLEI"
     gene            complement(21710..22384)
                     /gene="fsa"
                     /locus_tag="KRH23_001908"
     CDS             complement(21710..22384)
                     /gene="fsa"
                     /locus_tag="KRH23_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HHS5225188.1"
                     /translation="MQLILDTGNVEEIKELCTCLPIDGVTTNPSIVSKEKKNFKQLIN
                     EIGEIIGEDIPIHAQVLSTKYEEILEEALYISSLRKNIYVKIPVTQDGLRAIKDLHRK
                     GVKITATAIFTAHQGFLAAKAGANYIAPYVNRLDNISGDGVAMVSELIKIIDTYKMET
                     KVLAASFKNAQQVIELMQHGVHSVTVPYDICKSMMNHPLTDWSVDKFIEDWENTFGKG
                     SKTNNI"
     gene            22658..23422
                     /locus_tag="KRH23_001909"
     CDS             22658..23422
                     /locus_tag="KRH23_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HHS5225189.1"
                     /translation="MFAEERIQAILNILKKEGRVTVKELSSKFNVTEDCIRKDLKNIE
                     KISSIRRIYGGAVLARETLENQDTKDRKEINIPTKKIIAEKAFNLIEDRETIFLDIST
                     INILLAKLLAESNKKVTLVTNMLDILNVVTSKPNNLNIISTGGLLNLSLDGFVGTPTI
                     EFISKYKFDKTFMGSCGVDVFNSSLTTFEIEDGLTKKAIINSSKKVFIVMEDKKFKFD
                     GNFKFAHLEDISSIITEKTPTPDIVDILSEFNVNVL"
     gene            complement(23711..23932)
                     /locus_tag="KRH23_001910"
     CDS             complement(23711..23932)
                     /locus_tag="KRH23_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5225190.1"
                     /translation="MDRLKRDMKNMKEDLKEGVKKTAYVMKNTAEDLKDDAQGAMVNL
                     EMKKDEMMERYEQKKFSKELEKQMKNEMK"
     gene            complement(24333..25610)
                     /locus_tag="KRH23_001911"
     CDS             complement(24333..25610)
                     /locus_tag="KRH23_001911"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HHS5225191.1"
                     /translation="MRRIFDKWEKLSIKYKLFSITTSLLIALALIIYLILYFLLPSYY
                     HEYKIESLQESLKSLVDSSIHFDTYTLEERLYYMAKDQNLAILLKDNQGKIVYGKNEV
                     VILRYSKYMINSLEDEYRTSIPIYTKDAKDGPYTLELVMPLQPIDEANEVIRKLMPYI
                     ISIAILIAIIGAYIYSIVITKPLINIIESEREQEYRRKDFVATISHELKTPITIISGQ
                     IEGMIYSVGKYKDRDTYLKKSYECTQELKDLVNEMIEVSKSEILEKDLKLVSINISEL
                     LNRLVKRQVFLIEEKHMKTILKIEENLEIKADQERITKAINNIINNAIKYSPEESELI
                     IRLYDKNKRISKKTSNQRVVLEIENTGVTIEKRYLEEIFNPFYRIEKSRSRKTGGSGL
                     GLYIVSQIFKSHGFDYSIKNKENSVVFTVEFKN"
     gene            complement(25594..26262)
                     /locus_tag="KRH23_001912"
     CDS             complement(25594..26262)
                     /locus_tag="KRH23_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HHS5225192.1"
                     /translation="MNSSILVIEDDSNIQELISEFLSAEGYQVDTANDGLEGIQKFKQ
                     GSYDLVILDIMMPNLDGYGVCKMIRKSSSVPIIFLTALNDEGDQLKGFDLECDDYITK
                     PFSFNLLIKRVEAILRRSNKTINDKFIVFEKLKLDLNTYIAEIDGEPIELTLKEFNIL
                     KALIEKYPQVITREGLLDSIWGYDYYGDTRIVDAHIKNIRKKISLPYIKTVKGIGYTL
                     EKDI"
     gene            complement(26422..28923)
                     /locus_tag="KRH23_001913"
     CDS             complement(26422..28923)
                     /locus_tag="KRH23_001913"
                     /EC_number="7.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015662 - P-type ion transporter activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0019829 - ATPase-coupled monoatomic cation
                     transmembrane transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0140358 - P-type transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HHS5225193.1"
                     /translation="MSSNKVVESYKITGMTCAACAKAVERVTKKMDGVYDQSVNIATE
                     KLKIEYDNSKVNFDDIKQVVEKAGYGIIKEESNKKIDMKIDGMTCAACAKAVERVVKK
                     LDGVESISVNIATDKANIDYDPSKVKLSQIKAAIEKAGYKPIEEVRNKVDVDEDKLRK
                     EREMKSLFVKFIVAIVFAVPLFYIAMGPMIIKPIGPWPLPEIINPMTNTFNYALIQLI
                     LVIPVMIAGYKFYINGFKSLFSLSPNMDSLVAIGTLAAFLYSLYTTLQIANGQIQGMH
                     HHQLYYESAGIIIALILLGKYLESKSKGKTSEAIKKLMGLQPKTAIVLVDGKEVETPI
                     EEVEIGDILLVKPGTKIPVDGVVIEGYTSVDESMLTGESIPVEKNVGSKVTGASINKN
                     GVIKFKAEKIGGDTALAQIIKLVEDAQGTKAPIAKLADTVSGYFVPIVIAIAVVASLL
                     WFLIGGKDIVFVLTIFISVLVIACPCALGLATPTAIMVGTGKGAENGILIKGGEALES
                     AHKVNTVIFDKTGTITEGKPKVTDIVLNNNVKEEYLIKIASSAEKGSEHPLGEAIVKY
                     GEEKNIKFEKVDNFKAIPGAGIQVTINDESILLGNRKLMNDNNIKLGDLEEKSNILAS
                     QGKTPMYIAVDGNLSGIIAVADVVKESSKKAIEILHDMGIKVAMVTGDNAKTANAIAN
                     QVGIDMVLAEVLPEDKSKEVEKLQNQGKFVAMVGDGINDAPALAKADIGIAIGSGTDV
                     AIESADIVLMKSDLIDVPTAIKLSHETIKNIKQNLFWAFGYNTIGIPVAAGILYVFGG
                     PLLNPMIAAAAMSLSSVSVVSNALRLKNFKAYKRD"
     gene            complement(29207..29398)
                     /locus_tag="KRH23_001914"
     CDS             complement(29207..29398)
                     /locus_tag="KRH23_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1450 domain-containing protein"
                     /protein_id="HHS5225194.1"
                     /translation="MIRVCPNCSNVDVNKLKTLVGEENVKTGCIGQCRAFKKEAVGII
                     DNELEIKETEAEFFEACKE"
     gene            complement(29546..29788)
                     /locus_tag="KRH23_001915"
     CDS             complement(29546..29788)
                     /locus_tag="KRH23_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5225195.1"
                     /translation="MLEVTKIIIKYFASESDTFVKEEVCNFEELLKWSHKFIEGKKIE
                     DVLYIKSKENYKVNVIKSLEIKELEIVRKQQIPPYM"
     gene            30000..31823
                     /gene="typA"
                     /locus_tag="KRH23_001916"
     CDS             30000..31823
                     /gene="typA"
                     /locus_tag="KRH23_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0006950 - response to stress [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HHS5225196.1"
                     /translation="MSQKHKIINIAVIAHVDAGKSTLVDAFLSQSGVFRKNEVVKDCV
                     MDSNDLEKERGITIYSKNCAINYEDYKINIVDTPGHSDFSSEVERVMKTVDTVILLVD
                     ASEGPMPQTRFVLQKSLEFGLKPILFINKIDKKDQRAEEVVNEVFDLFVDLNATDEQC
                     EFPIIYGIAKQGIAKLEMDDDSEDLSPLFKTIVNHVEAYPNYDNEPLQFQISALAYDD
                     YVGRLGIGRIYKGTLKNNTQVAICREDSVVSKGKVSKLSVYEGLKQVEVDEATSGEIV
                     VIAGIPDISIGETICDLDSPLPMEMIKIEEPTLSMNFLVNDSPFVGKSGKFVTTRHLK
                     DRLEKELEVNVGLKVEPLDTTDGYKVSGRGELHLSILLENMRREGYEVGVSKPEVLMH
                     KEDGKLMEPIERVVVNCPEVYSGTIINELNMRKGMMESMSIEGDYVKIEFLAPTRGLL
                     GYRSEFINATRGEGTLVRSFEKFEEFKGEIPSRGNGVLIAQGPGVTMGYSLNALSDRA
                     VMFVDPGVEVYEGMIIGMNSRKDDMVVNPCKNKKMSNVRASGSDDAIKLSPPRIFTLE
                     EALEFIEDDELVEITPDSIRLRKRFLNEHDRLRYNKSRQGK"
     gene            complement(31913..32821)
                     /gene="trxB"
                     /locus_tag="KRH23_001917"
     CDS             complement(31913..32821)
                     /gene="trxB"
                     /locus_tag="KRH23_001917"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004791 - thioredoxin-disulfide reductase
                     (NADPH) activity [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA];
                     GO_process: GO:0019430 - removal of superoxide radicals
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HHS5225197.1"
                     /translation="MVDIIVIGAGPAGLTSAIYAMRAGLSVTVFEKNIYGGQVASTSE
                     VENYPAVQKISGVEFSNNIYNQAVAQGVDIQFDEVEEINLEGKVKVVKTSSGEHKAKA
                     VILANGVERRKLGCAGEQEFTGRGVSYCATCDGAFFKDKEVAIVGGGNTALEDALFLA
                     NNCTKVYLIHRRDSFRGEEVLEKSVKARENIEILYSHGVEKIEGEKTVSKIEVKNLKT
                     EEKRTIDVSGIFIAIGLKPNNKMFENVLDLDEGGYIISDESCTTSVEGVYVAGDSRTK
                     FLRQIITAASDGAIAAVQAANYINVE"
     misc_binding    33623..33854
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            33962..35443
                     /gene="thrC"
                     /locus_tag="KRH23_001918"
     CDS             33962..35443
                     /gene="thrC"
                     /locus_tag="KRH23_001918"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004795 - threonine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0009088 - threonine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HHS5225198.1"
                     /translation="MYYSSTRGTKEKVTASQAIIKGISNDGGLYVPSEFPNVKNELIN
                     LVNLTYSQIAFFVLSKFLCDFTEDEIKNCIENAYDEKFDCSSIAPLNKVNDTYFLELY
                     HGPTLAFKDMALTIMPHLLKTSIKKDNLEKDVVILTATSGDTGKAALEGFKDIDKIKI
                     IVFFPEDGVSPVQKLQMKTQTGKNTYVVGIKGNFDDAQSGVKKIFSDKEFNQKLLDNN
                     YILSSANSINIGRLLPQVAYYFYSYMKLVSNSDINLNDKINFVVPTGNFGNILAGYYA
                     KQMGLPINKLICASNDNNVLYDFFKTGVYDKNRTLKLTTSPSMDILISSNLERLLFEI
                     SNRNTDIVNKLLSDLSDKGVYKISDDMEKNLASFYGEYSNEEEVKSTINNVFKNYNYL
                     IDTHTAVAYNCYEKYKKETSDNTKTVIVSTASPFKFSEDVLKSIDCDFKDLDDFAIID
                     RLSSISKIDIPKPIKNLKNAEILHKDIYEKDELKLAIKKFLKV"
     gene            35453..36346
                     /gene="thrB"
                     /locus_tag="KRH23_001919"
     CDS             35453..36346
                     /gene="thrB"
                     /locus_tag="KRH23_001919"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004413 - homoserine kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0009088 - threonine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HHS5225199.1"
                     /translation="MLEIIVPATSANIGPGFDCLGIALNIYNKFYVEEIESGLEIEGC
                     EDAYKNENNLVYTSMKYFFDRVKPEKIPAGIKIKIQSEVPICRGLGSSASCIVAGVIA
                     ANALSGANLDKNQLLNIASEIEGHPDNVAPAILGNMIVSVTDNENIHYDIIKIPEELK
                     FCAMIPNFKLSTEKARGVLPKEIPYSDGVFNVSRVALLISALLNKNFDLLKVACQDKL
                     HQDYRGTLIENYNDIVEKSEQLNSIGVFLSGAGPTIMSLIKENDDSFVDNMKNYLQKL
                     KSDWEIKELCCDSNGAVLNII"
     gene            36473..37531
                     /locus_tag="KRH23_001920"
     CDS             36473..37531
                     /locus_tag="KRH23_001920"
                     /EC_number="1.13.12.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004497 - monooxygenase activity [Evidence
                     IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016703 - oxidoreductase activity, acting
                     on single donors with incorporation of molecular oxygen,
                     incorporation of one atom of oxygen (internal
                     monooxygenases or internal mixed function oxidases)
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent flavin oxidoreductase"
                     /protein_id="HHS5225200.1"
                     /translation="MIKELIIRDLVAKVPIIQGGMGVGISRSSLAGAVAKLGGVGVIS
                     GVQIGYDEEDFETNTINANLRAIKKHISKAKEISNGGIIGINFMVAMKEYETYVKEAV
                     KAGVDLIISGAGLPNKLPSLVKGSNVKIAPIVSTAKAANVILKMWDRKEKTTADLIVV
                     EGPKAGGHLGYSNEELDNIDSIDYDKEFVEILKVANTYGEKFGRNIPVVAAGGITSSS
                     DVKKYIDMGASGVQVGTRFVATYECDAHENFKMAYINASEEDVHIVKSPVGLPGRAIR
                     NKFIEEVKINRPEIKKCYNCLIPCNPKETPYCISQALINAVKGDVENSLLFCGNDAYK
                     IDKLSTVEDVINELISEL"
     gene            complement(37686..38198)
                     /locus_tag="KRH23_001921"
     CDS             complement(37686..38198)
                     /locus_tag="KRH23_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HHS5225201.1"
                     /translation="MSDFKEILAEEIKNNPFGLIGKDWTLITAENEGKVNTMTASWGG
                     LGVMWGKDVAFVVIRPQRYTKEFIDNTDKFSLTFFDEDFRKELSYCGKVSGREEDKIS
                     QIGFNIEHLNDTPYFKEAKMAIICKKMYSQKLEPQCFIAEGIDGRWYPQKDYHTLYIA
                     EITNVLVKED"
     gene            38718..39653
                     /locus_tag="KRH23_001922"
     CDS             38718..39653
                     /locus_tag="KRH23_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HHS5225202.1"
                     /translation="MIRYYKTIDSKLEKLSFFEDGCWINLVEPNHSEINEISNLLNID
                     VESIESALDEEERSRIDVEDNHTLILIDIPVDESDSNSSHYTTIPLGIILTEEAIVTV
                     CDAQTKILNDFIVGHIKDFFTFKKTRFLLQILHKNAAYYLHYLRKINKMTIIIEREIY
                     KSMKNKELVQLLELEKSLVYFSTSLKSNELVLNKMVRTAGIKKYPDDEDLLEDVIVEN
                     RQALDMAKIYGDILSRIMDAFSAIISNNQNNVMQILTVVTLIFSIPTIISGFFGMNVI
                     NMPFSNNPNGFWIILLITSIICIVITFFMSRNKLL"
     gene            complement(39745..41616)
                     /locus_tag="KRH23_001923"
     CDS             complement(39745..41616)
                     /locus_tag="KRH23_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HHS5225203.1"
                     /translation="MKNTKFSIKKIKNISNDPKVVHTKGALLEKMGKMESAIELYKSA
                     ALDNYVKSQYTLGNIYESKKQFKEAEKWYSMAYKSGSEDAAFDLGNMYYKLDGYEYAI
                     YWYEKIANLGYLQAQNNLGVCHFKMKDFVRCEKWLKTAADKNLGKACFNLGVLYTFLE
                     KDDEAYEYYKKGSVLLDDDAKYNLAILNGKKKDNKSTVSLYKQLYKSGHMKGCFNLGM
                     IMEINDNLEDAEKYYKKSADRDDVKSEYRLAYVYDRKEELGDAIYYYEKAIEKNHTLS
                     KYRLANLYNRENEIEKAKTYYKMAAEDDITEAKNNLAGIYFEEKDYENAIKYYEDAIA
                     VGCKSSLENLGDLYYQNQDIEKAISYYSRIPNNVSCQIKLGNIYEDLNNIEEAISWYK
                     KASENGDTRSSYRLGCIYESLGNTKNARKYFEMASSKNHMNARIHLGRIYFREGKLEE
                     SKMMFDTPANENNVYAQHMVGLIYDMFYKDYVNSKFWYEKARAQGCVESIYNLGQIYL
                     KLNDDAEAEKYYKEGIKYGSKKCEYMLAGLYYKKSLDMYVSLANEEYDNCEEIVEGFP
                     NLNIDFDEVLIPPFKLQEEVIDEEEYVPIYILNIKESLDSMLEGLETEMIIDEEHDS"
     gene            41806..42732
                     /locus_tag="KRH23_001924"
     CDS             41806..42732
                     /locus_tag="KRH23_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HHS5225204.1"
                     /translation="MNFSNIFIQVAVLFIIILVGYFVRKFNLLDDHCTSKLSTLTMTV
                     FLPSMIISSMQINFDSKMIQKILLLLFTSLIMYIVSIIIAFLLKYILKCNDKKDLGIY
                     QYIVVFSNVAFMGYPVIEAVLGHEAIFYTAIFNLPFNLFSFTLGIYLLSKGSTSRGFS
                     IKSLISPATIAIVIGLFLFVTGLRLPQFINEPLEMLGSITTPISMIIIGSLLANSSAL
                     DCFVNKKLYIVTFIRLLVLPVIVYFILKGWINDKMILAIPVVISSMPAAANTAIMANQ
                     YDSNITLASQCVFFTTLFSVISIPFISILLLS"
     gene            42871..43017
                     /locus_tag="KRH23_001925"
     CDS             42871..43017
                     /locus_tag="KRH23_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5225205.1"
                     /translation="MDMDLLFKIVFAIVAIGVSVKIIKTVASLAFKIALILLIILFVY
                     RMFL"
     gene            complement(43122..43646)
                     /locus_tag="KRH23_001926"
     CDS             complement(43122..43646)
                     /locus_tag="KRH23_001926"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HHS5225206.1"
                     /translation="MSKPIDITIRPIRREDAQAFNEIRRTYSVMRNTLALMSDRVDKT
                     EAMLASLGENDYMFVAETNNNGEKDVIGFAGLHVNSSPRLRHSAEIGISVAENYQGRG
                     VGKKLMEQLLDIADNWIMLTRVGLEVIVDNEKGLNLYKKLGFEIEGTKKYAVIRDGKF
                     EDVYIMGRYNKNLI"
     gene            complement(43699..43923)
                     /locus_tag="KRH23_001927"
     CDS             complement(43699..43923)
                     /locus_tag="KRH23_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5225207.1"
                     /translation="MIIKLTKDNFNFRFKQYEGMFFHAEVVEGMESIRYKITKDKEGT
                     ELKEFGSTHIKDNMIYVPQVEAYIDLNSIK"
     gene            44120..45244
                     /locus_tag="KRH23_001928"
     CDS             44120..45244
                     /locus_tag="KRH23_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3810 domain-containing protein"
                     /protein_id="HHS5225208.1"
                     /translation="MSKKTKYFSLILFPIALLLNFIASKVPNIVEKYYSQFIDKIIVQ
                     ILSKVSGIFPFSLYEITMYIIVISIFLFLCCTLSTIFNKKKKLNIYLKNSILNILSIV
                     SIVYFLFVVLWGINYNRIPLETTLINNYNLKNNTSIQSKQYSVKELTKLYKFLVIKAN
                     ETRKLTLQDKNGIVKSNTDYNGVINRAQLGYDNILDILPSVSGSYSKPKYIISSNLMC
                     YTGITGIYFPFTGEANVNIAIPDLYIPCTVEHEMAHQRGFASEDEANFIAYLTSIKHP
                     NIDFNYSGYILALNYTASALSKVDYNAYVDISAGISDSVRRDLKNESEFWQKYEGKIN
                     EISNEFNNSYLKANGVTEGTQSYGKMVDLLLTYYELYPYN"
     gene            complement(45718..46542)
                     /locus_tag="KRH23_001929"
     CDS             complement(45718..46542)
                     /locus_tag="KRH23_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5780 domain-containing protein"
                     /protein_id="HHS5225209.1"
                     /translation="MRYKKISSLPILVVALLITGTTTTFSLSTTNSEKTNVYLANTVS
                     TVTKKVSDIQSSKGLVYNENIPLFINNSKIQYDDTPYHWPSNVISLTNSSEKAIMDYE
                     ITCLAYDKNGKPLELYWDAQNVAADGEVGSVGFSPAGVDYGIVTGISPVSPKSYSHTY
                     RKMQQSPPQDIISMFEKQQGKAWVENWLKEWKQMEKEYAKQNAIAPGKNQNDAFLLFD
                     KWKQSTGEHGVKYIISCVKQVTFNDGSVWKNSAYENWLKSFQGKEVSNSVLENYYK"
     gene            complement(46890..47945)
                     /gene="ispG"
                     /locus_tag="KRH23_001930"
                     /gene_synonym="gcpE"
     CDS             complement(46890..47945)
                     /gene="ispG"
                     /locus_tag="KRH23_001930"
                     /gene_synonym="gcpE"
                     /EC_number="1.17.7.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046429 - 4-hydroxy-3-methylbut-2-en-1-yl
                     diphosphate synthase activity (ferredoxin) [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin-dependent
                     (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase"
                     /protein_id="HHS5225210.1"
                     /translation="MSYERRKTREVSVGTVKIGGENPISIQSMTNTDTRDADATIAQI
                     KRLEEAGCDIVRVAVPDIKAAKNIAKIKSSVNIPIIADIHFDYKLALEAIEQGVDGIR
                     INPGNIGSIERVKMVVEKCKERNLKIRIGVNGGSLEKELLKKYGSATAEALVESAMGH
                     IKILEDLDFHNIVISLKSSDIYKTVDAYELISKRVDYPLHIGITESGSVHKGTIKSSI
                     GVGALLLKGIGDTVRISLTGDPVEEVIVGKQILRSLGLLNDKIKVISCPTCGRCNIDL
                     ISVVNEVEEKIGSMEKNITVAIMGCAVNGPGEAREADIGIAGGKGEGLLFKKGEIVRM
                     IDGNKLVDELLEEIEKL"
     gene            complement(48128..49132)
                     /gene="rseP"
                     /locus_tag="KRH23_001931"
     CDS             complement(48128..49132)
                     /gene="rseP"
                     /locus_tag="KRH23_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HHS5225211.1"
                     /translation="MTIIAALILFSIIVLIHELGHFIFAKRSGIKVNEFSIGMGPKIY
                     SVKKDTEYSIRALPIGGYVSMEGEDEEQISPNSFGNKSILQRFSTIVAGPIFNIILAA
                     ILLVPVFLYIGSPTTKLGKIMPDTPAQAVGLQVGDKINKINGNSVKTWDEVANIINTS
                     SGGELKLSITRDGSDKVVNVTPKNNNGKYEIGIQPQREKDFLGSIVNACKTTVDMTKQ
                     MLTFLGQMITGRVPGGIGNAVAGPVGVIGMVSDAARTGIINVVYLAAVISLNLGIVNL
                     LPIPALDGWRILMLLLEAVRGGKKLDPNKEGMINVVGFGALMLFMLFITYKDILRLFQ
                     "
     gene            complement(49145..50299)
                     /locus_tag="KRH23_001932"
     CDS             complement(49145..50299)
                     /locus_tag="KRH23_001932"
                     /EC_number="1.1.1.267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0030604 - 1-deoxy-D-xylulose-5-phosphate
                     reductoisomerase activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0070402 - NADPH binding [Evidence IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate reductoisomerase"
                     /protein_id="HHS5225212.1"
                     /translation="MKKISILGSTGSIGKQTLDVVRDNRDKFEIVAISANSNIELLLE
                     QIVEFKPKYVTVFEENKALKLKEMLPKNIEIEVLAGMEGLKIISSLDEVDVLLTAVVG
                     MIGLVPTLCAIKKGIDIALANKETLVTAGELVMKEAEKYNVNILPVDSEHSAIFQCLN
                     GENKKNIEKIILTASGGPFRGKKKGELANITKNEALKHPNWSMGRKISIDSSTLMNKG
                     LEVIEARWLFGVEQENIDVVVHPQSIIHSMVQYTDSSIIAQLGCPDMRLPIQYALTYP
                     DRMESSFERMNFSKFSTLTFEEPDLETFPCLKLAYECLKMGGTYSSVLNSANEVLVSE
                     FLEDKIGFYDIPYYIEKTLEVHSSISEPTLEEILETDRWSRAYVANLIKK"
     gene            complement(50463..50666)
                     /locus_tag="KRH23_001933"
     CDS             complement(50463..50666)
                     /locus_tag="KRH23_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHS5225213.1"
                     /translation="MISYAPLWKLLIDKKIKKMEFVNISGISISVLGRLGNDKSVSMD
                     TMEKICLALDCKIEDVVEIKKGI"
     gene            51003..51584
                     /locus_tag="KRH23_001934"
     CDS             51003..51584
                     /locus_tag="KRH23_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5225214.1"
                     /translation="MLYLLKINQFEKSYDIGIFKNEQSIYKFIEKIPFVKKDNSNFNY
                     TNYYMEFEDIPEYYEVNFNNYLYIITRFSFIPDGTEIFFTWEEIHCWDEKVATEKTFI
                     NGETLVDSYNFPNNEVKDYIQKRESLYIETKKYYEEKGLKIERHALGSEDGEYVELTN
                     DSILYLLDIEAVEIREQSKNIEEFLYKYKKRFK"
     gene            complement(51672..53483)
                     /locus_tag="KRH23_001935"
     CDS             complement(51672..53483)
                     /locus_tag="KRH23_001935"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0052621 - diguanylate cyclase activity
                     [Evidence IEA];
                     GO_function: GO:0071111 - cyclic-guanylate-specific
                     phosphodiesterase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="HHS5225215.1"
                     /translation="MKKKYDFLIYSAIWLVIIILFIFSLYHSIEHIKIISHTGTIRSE
                     TQKVVKQELNNERNDDLIKRLDNILIKLRTGNGENGFQRCDNKEFQQKLNQMDSMWES
                     MKKEIIEVRNGASGDKLYKLSEEYSVLSNQIVFISEKHSNAKLYSFATALFIYLIFST
                     ISLLIWEYYNKKRFKRIFYTDNLTKIKNQVAFENRAIEILHNASNKEYVLLNIDIDNF
                     KYINDTHGYEYGDKVLIIVAAALSKTFNIKETCARIGSDNFVILAKYRDSLLEDIREM
                     LTNAIISELDMNVTQTISYCIGAYLVEIDNLGYKSINSIMDKANIAHKVSKTRGISST
                     VWYNENLLKQLQMENSIYNYMYKAIENEEFHMYLQPKFQISSLNVVSAEALVRWFSPE
                     LGFLSPDEFIPLFEKSGFIIELDFYMLKKACSFVKKTFMKKNQYTYPIAVNFSRVTIY
                     QNSFYQRFLDTVKEYEIPFKYIEIEVTESAFNEISQPVISILEELKKLGFLISMDDFG
                     SGYSSLSLLCSLSINGLKLDKSLLKETFNQEKVYSIIQCIIEMSHRIGMSVVCEGIET
                     KKDLEFLNTVKCDVGQGFYFSKPIEEKEFFNKYVTKK"
BASE COUNT        18521 a         8596 c         5990 g        20804 t
ORIGIN      
        1 ttatttttaa aatttataat taaaaattat cttttttaaa tcattttttg tgttttttat
       61 atcatctaac ctcacagttt ttgcttctat aaacttaccc ttaaatgatt ctgataattt
      121 ccaggaacta taattcttat ctttttgaat acaaggatat aataatatac atctttttgc
      181 attttcatat gctgttatat atgcatacat ctggtatata tcacttgacc tataaaaaac
      241 atttgaatct acttcaatag ctttccattt agtgtcaatt ataatttcat attcattttt
      301 taagtcatat aaaactatat ccggtcttaa attaaagttt ttcttaccag tttgttcatt
      361 tttcaaaaga aatttactct tatcttgtat atatgtttct ctaaatgaat tgtcccatat
      421 acttttgatt aaaattccta tatattcttc atacaaagta tttatttcaa ataatataga
      481 aaatgcctct tgattatttt gactattatc catagacaaa tttaaaagta gaagtctagc
      541 taataaataa caatctttaa atctatcatt gtttttataa aacttataat ccaatagttt
      601 ttttctatct atataaatta aatctacatt ttgaaaatag cttaaaattt ttttaatctt
      661 gccttgaatt gaattgtcat ttattctaca taaaatagat atacatgctt ttttaagaac
      721 ttgattcaag aaattatttt cactatactc atcatattca catcttattt tcattggaga
      781 aatgcctttt tcttttgcat atgtacttaa taatatttta cccctcataa catttaagtt
      841 ctctatttta tttatatatt caaaataaat accttttttc atctgtgttt gcatactctc
      901 aatgaaatac ataacaaaaa aatttaagag attataattt ttcaaactca atcttatttt
      961 ttcattcatt gtaattggaa ttttattaca tatagaaagc atctgtaata gtatctctct
     1021 atcttttaca agattatcac ttaatgacaa tttaggaagt atttcaagta ttacattttc
     1081 aaaacatatg atgcctacat agtttataaa tctaagtttt ttgtatttaa tatctattat
     1141 attacttttt aatacatcat tattgttctc tagatactta agcaattttt catattcaat
     1201 ttctgtaagc tcattttcac cattacctac ccttatccat tcataagttt ccttaacata
     1261 tatattttta ctcatatata ttttttagct cctcactaga tatgttttgt tttatacaat
     1321 agttaacttt actctccatt attgaggcat tattattttt aaataactca gaagctataa
     1381 gtttttcttt ataaacaatg tatttatctt tttcatttct tccaattcct cctaaaatca
     1441 aacctacttt ttctgaatca taataaaaat actcttgaag aagtggtatt attttacttc
     1501 taaatactac tactatatca ttaatatttt ctacagcaag tagataagct tgtccaataa
     1561 catggtctct atcatataaa aactctatcc ttttattgat tgtatatagc atttttctaa
     1621 tatctatacc atctacaata gacaataaat cataatctgg cataatttct tcaaaattaa
     1681 accttcttct taaagctata tctaaaagtg ctattgattt atctgatgtg ttcatagttc
     1741 caactatata caaatttgga ggtagagaaa atttttcctt tgaatatggt agtttgacaa
     1801 tagtttgatt tgatttagta agtcttttat catcttccaa taatgttatt agctcaccaa
     1861 atattttaga tacattccct ctattaattt catctattat taaaacatag ttttctgatt
     1921 cttcaaaatt aaaactctca ctatattcta tattttctaa tactaatttc tttttcctgt
     1981 cttttatagt ttctaaagtc aagctatctt tttccaactc aaagctcatc tttttttcaa
     2041 atttcaatgc attataacat gcttctatag atatatcctt taatatccca tcttctggct
     2101 taaaattgcc ttcaccatca gacttaagac cctctataaa ttcctcatat ccatatgatt
     2161 gatgaaatgt acaaaattct acattatttt tataatctaa gtaacctgta tagtatctgt
     2221 ttcttagact ggtttcactt actagattgt aaaccatctg ttttgtattg tatgttttac
     2281 cagttcctgg tggtccataa agtatagtat ttaatggcat tttattagta aatcttttta
     2341 catacttttc aactatacta ttattttcaa atataaccca tgcatttccg tctatattct
     2401 ccttttcata ctctatccat ctaacaggaa aaaaatatcc accctctaaa gcacttactt
     2461 tctctttatc gaacccttcc ataacttgac atacgccaaa tagactcttc attgtatggt
     2521 cattttcaca aattactttc tcgctattat acaataaaat ataatcatct gtctttatat
     2581 tttttaggct ttctaattgt tctagattaa tgggctgaat aaataattct tcatcatcta
     2641 cacacttatc tacattttta taataatagt tttttaaata ccatttatta ttttcacttt
     2701 cttctattct ttttctcaat aatttcttat cttgtgactt aataatttct aaatatgagc
     2761 taatatcatt attatttaat ttataaaatt cacttgtata tactttacaa tttgaaactg
     2821 tatcaaaatt atgcatccat tttactggta gtgtatgccc taaaatatga cttaattcat
     2881 atccattttc aaaatcttct tcaactatgc caatagacac attacattta actttttctt
     2941 ctatattttg atatgcttta tataaaaaat aatctccttt tttaatcgac ataaactttt
     3001 ttataaaatc tttatcatta caattctcat taatatactt ttctgatttt ttccccatac
     3061 taaatacttt ttttaaattt atttttatat caaatccaag tgcaattatg ctttcttctc
     3121 taaaaatctg tggtgtgtct gtttcctgat aaaaaaattc ttccattaac caatactctg
     3181 tacctcttat attttcagac atatacactc tccttaatat ctaaaatata ctaattatac
     3241 aataagccta ctctaatatt tccatttaaa ttttccttta tatataaaga aaatattact
     3301 tcatagcttt cttctacctt gctctgaata ttacttatta aatcattcaa ttccattata
     3361 gaaaattctg gacttccttc aacaaataca attcctttct tacttataaa ttcctcacca
     3421 atatattcca tcctgtcaaa taaaatgtca gctatctcgc tatatgactt tgtatcttca
     3481 aactcttcaa aagaatactt aattccttta tctcctacag tagcttcttt taaatcagta
     3541 atatctatat ttatcatgca agaatcagaa atagactcta ccatgatatt cattaaatca
     3601 acaaatttaa atatactatc attattgatt ttaaactctc tcccaagctc taaatcttct
     3661 ttattttctt tctctgaaca atccattcct atagatagaa ctcttctttc gtttgacata
     3721 tatgaaacag cttttataat atctctaata tgtttatctt cagatgaata tatcaaaaat
     3781 aatatatcta caccatctaa aagacttcta acatattctt tttcaatctc ttgatttatg
     3841 tttatttttt ctatatccat atttgctttt attttttctt ctacttcatt tattatatta
     3901 ataccttcag ctccaatacc aattatttta gcattcttat taaaattttc cattataacg
     3961 tatatctcct taataattat ttaatttcaa catttctaaa tattatacca tattttcttc
     4021 ataaaaatat cttaactcat tggccttatc ataaagtagc ttattcaaaa attttggctc
     4081 tataacctta gcattatttc caataaaaaa taaaatcgaa gcataacaat ctatatcttc
     4141 aacctttatg aatgtactaa ttattccact accatcttca tttagctcca tatctaaatt
     4201 ccaagaactg tcctttattt tagaaacacc ttctttagtt aataatacat ttagataaat
     4261 aatttcacca aattttttag tagttgaact atttccatat aaattgttat atacttcatg
     4321 taaccattct tccaagttta tatgtatttt tttactttct cctgttcttt ttatatcaat
     4381 tatattatct atatgaacta atattatttt atcactttta caatcatatg ctggtgaaaa
     4441 ccatgctccc ttatttaaat atatacctat agggcatacg tttttttcca aaatctgatt
     4501 accacactta tacttaatat ttaaaattag agattctgaa gaagctctaa aaaactcagt
     4561 tacattacta ctcttaaaat ctccatcatt agtatcatta gctacaaagc caatgtatct
     4621 tttaatattt tctataccta cttttatact gcttttacgt tcataactta cttttctcat
     4681 tatagaatta atttctattt ccattaactt ataattataa atctgaagtg acttaagtgc
     4741 aaatagtata atcataactt ctttttctgt aaatataaca ggaggtatat agctattatt
     4801 tagcacccta taacctccat ttctaccttg ttctgcttga attggaagtc ccattttatt
     4861 taattctttt aaatatcgtt gtattgtttt agctgaaaga ttaaattcct ctgacaactc
     4921 ttttattgta aacttttgct tatcattaat atatatccaa acatcagtca atctttttac
     4981 cttcgacaaa taaacacctc ttttcactaa taatactctc aattaattaa attactatac
     5041 actatttaaa atttaatatt aatgacattt ttatattttt tcattaaaaa acagaaaaat
     5101 ggtactccta caattgttac tactacaaat tctccaaaac ctacctgtat catagataga
     5161 attaatggaa gcccaaagaa tacatttaac attagaccaa ccacaatcga atttataaca
     5221 gttggccata aagaagctat aactaaagta cttttatttt gtttacctaa ctttctagta
     5281 atataaatca tacttgcact tataaatgtg gctaatgttc caaaaattat atcaggtaca
     5341 ccatatggtc ctattacatt tgctaaaaaa caacctaatg taagacctac tatatatcct
     5401 ttatctaaaa atgccaaaag catcataatc tctgctaccc taaattgtat tggtccataa
     5461 cttataaatc ccaatgataa tgttaaaact gcatagattg ctgtaattgc tgcagttagt
     5521 gctatattaa tactattttt tctcatatct gtctcctagt aaaagtttta tttttaaaaa
     5581 aattaataac ataactttat tttatacaaa atctataaac ttaaacagta attttataaa
     5641 aacaaattat tttagcgaac tattttccca attcatttta tattatacaa tataatacat
     5701 acaaattcaa ttttatatat atagaatata tgatattaaa attatataca aactaaagat
     5761 aaattttcta ttgttaatta aaaacagcaa aaaagagcct taaaattagg ctctaataat
     5821 ttattttaaa atcagtgaac tctactacca tcttttaatt tagataatat catccaagta
     5881 cctatacaat caatttccag ttgtttctct atttcatcat ataacatttc ttgatatgat
     5941 gtatttaaaa caacattttc aaccaattta gaaatttcct cttctgcaaa atcaatttct
     6001 atttgatttt gtttttcttt aaaaaatacc cttacttttc tctgacttat tgaacgaccc
     6061 tcaaagctga ctaaacattc taaaatgttc ttatctcctc taaaattatt tactgctctc
     6121 atattattta gattaccagc caaaacatca tccccttatt taattttgta ttttataagt
     6181 aaaattcata atattataat aactacttat taaatatctt tcaacaggta tgacataact
     6241 ggttgtttaa catgtaaaac tagtctaaat tttcataaat aattatttat tcatttccat
     6301 aaaaactttt tcaggtgtaa tagggagtgt atttattctt acaccaattc cattaaacac
     6361 agcttcttgt attgctggta aaggtgtatt tataacaact tctccaacag atttagcacc
     6421 aaatggtcca gttggttcat aagtttcaac aaaatctact ttaacatttc caatatcaca
     6481 tctagctgga atcttgtatt gcataaatgt atttgtgtcc atgcttcctt tttctgtgta
     6541 tctaacttct tcaaataatg ccattccaat cccttgaaca attccacctt caacttgtat
     6601 cttagctaaa tttttattta taactgttcc acaatctact acagctacat aatttactaa
     6661 atcaactttt ccagtttctg tgtcaatttc agtttctgca aaacctgcta taaaaggtgg
     6721 aggagatact gggctaccat gagaagcaag acctattaat tgattagtat ctggaccaat
     6781 tgtagaatca actgctatat cgaataataa agtgctacct tttttactag ttaattttat
     6841 accatcaaat tctacttcat ccttatcgac acctagttta gttgctccag cagaaattat
     6901 tttttctctt aagtcttgag ctgccttaac tactgccata cctgttacat aagtagtact
     6961 tgaagcatat gaacctgggt catatggaac taagtcagta tcagctgata taactgttat
     7021 attttcaatg cttgtatcaa gaacctcagc agccatttga gctaaaatcg tatcacttcc
     7081 tgtacccata tcagtagaac ctatcataag agtataatct ccacagtcat tcaattttat
     7141 ttcagctgaa gacttatcaa gaccttgtat accagaacct tgcatagtaa ttgccatacc
     7201 cacacttcta atttttccat tgtcaaaatg tttacaagga tatttttcat tccatccaat
     7261 aagttctttg cctttattta tacattttat taaatcgaca ctatttaaag ttttaccata
     7321 tgcaaatgta gtttcacctt ctgttaccac attttttaac cttaaatctg ttgggtctat
     7381 ttttaattta ttagcaagca tatttatagt tgattcaaca gcaaaacacc cttgtgatgc
     7441 tccataccct ctaagtgctc ctgctggcat cttattagta tataccacat ctgcaataaa
     7501 tcttgttgct tcaactttat tatacattgg taaagttttt tctccaacca aaccaatagt
     7561 tgtagaagca tgctctccat atgctcctgt atcagaaagt gcttttatat ctattgcctt
     7621 tattatgcca tcatttgtag cacctagtct aacttttaat ctcattgcat gtctacttgt
     7681 tgaacaatta aaagtttctt ttctatcata aattatttta gctggtttcc ctgtttttaa
     7741 agtaacaatt gcagaaaaaa tctcaacaca tgcagtttgt ttaccaccaa atccgccacc
     7801 aattctaggt tttataaccc taattttgct agctggtatt tctagtgcac gagataaatg
     7861 tctttttaca tgaaatggta tttgagttga acttactaca accaatcttc ccatatggtc
     7921 taaataattg tatgccctat acgtctccat cattgcatgt gcttgagctt gagtataata
     7981 agtttcttca atcactacat cacaattact taatactttt tctacatcac cttttgtata
     8041 atcatgatgg gatactatat ttttttctct ttgcatacct atatcaaagt tacaatgtct
     8101 atcttcatca tgtaccatag ttttatttcc tattgcctct tcaaaatcca aaacaggtgt
     8161 aagtacttca tactttactt tgataagatt cattgcttta attgcagttt tttcatctat
     8221 agctgccact atagctactt cgtcacctac atatcttaca acatcttcaa gaattaatct
     8281 atcatatgga gatggctctg gatatgtttg accagcaagt gtaaattgag attttggtac
     8341 atctttatat gttaaaacac attcaacacc atcaaccatt tctgcctttg atgtatctat
     8401 atcttttatt tttgcataag cgtgaggact tctaagtatc tttaccacca aagcatcttt
     8461 tgctgataaa tcatctgtat atacaggctt tcctgttgtg atactcattc catctatttt
     8521 cttgattcct tttccaacta tattcatgtt ctattttacc tccagataag ttttgatagc
     8581 tcttaactgt cccatatacc ctgtacatct acatagattt cctgtaagat aatgctttat
     8641 ttcatcatct gtaggatttt caagctcatc cttcattgca agtacagtaa gtataaagcc
     8701 aggagaacag aaaccacatt gctcagctcc ttcttttacc aaaacttcac taaattcttt
     8761 aacttcattt tctaaacctt caattgtagt tatttcttta tctaaagctc tcaatgtcag
     8821 tgttgcacaa gataatgtag gtttcttgtc aattaaaact gtacataaac cacaacaacc
     8881 tgtgtcacaa cctcttttca cacttaaatt accaactttt cttaaagtat caaccagata
     8941 ttcttctggt tctatatcaa cacttttttt cttcccattt atattaatct ttactaacat
     9001 taaataacct ccattatagc tctttttaaa agtactttac tcatagcttt tctatactcc
     9061 ctagatgctc tcatgttaga accaaaagtt agttcttctg atgctatttc tactgcttta
     9121 tctatattaa tttcattgat ttcattgtta gatagaaatt cactagcttg ttttgcaatc
     9181 gtagctttct gcggtcttgc tcctacacat aacttaaatt gttccatatg ttttgataca
     9241 gatacattta gaattggata atcactcttt gcatttctaa gtgatttata agaagcattc
     9301 ttatttgtct tctttatgta tatcttaata agtaaatctt tctcataatc tctatttaga
     9361 aactcttcaa gactaattct cccaatatta tataattcta cttccgtatc taatgaaagt
     9421 aatgctacta tcaagtcaga aaaaccatat ttagaaaata ctgttgcacc aactgttact
     9481 acatttctaa actgaactcc tattatattt ttaactgaat cttctattat tcttccaaaa
     9541 ttatttttta ttatggaact tgtttctaat gttctaaaag tagtcataga accaatctca
     9601 acgtaatctt catactcttt tatataatct aaatttaatt tagataattc tattcctgtt
     9661 cctattcttt ttttccccat tcttaaaaaa gcacttccac caattacttg gttagttttt
     9721 cttttattta aaattgagta cgcttcttct actgtatctg gctgtacaat atccataacc
     9781 gtaaacataa atttcctccc ttatttgcta ttcttatttt aaatacaact aattatatca
     9841 tagcttcaac aaattttgat aataaatatg tctaatatgt aaattctgta aattacttat
     9901 acataaaaaa atgactattt caataatcat cattagacaa tattaaaata gccattaaca
     9961 ggtactattt taaagcaaaa ctttaaaaag ttgatacttt ttcacttata tttatcactt
    10021 cttcttctaa taatccaagt tttttagcta ctaattttgt agtacttcct tgtattacta
    10081 atgtaattag tatagtcatg aatactacag atgaaatcac ttcgtatcca ggaactttca
    10141 ttgctgaaat aataccacaa agtgctgctg gtattacgcc tgtttccctt acccacatca
    10201 taaataatat ttcactttta ctccattttg cttccctgtc tacaagtgta caaactaaaa
    10261 cgcaaagtgg tcttgctata aacattaata ctaatactgt aattacagat ggcataaaat
    10321 atttacttaa ctgagccaaa ttaacttggc tacccaatat tataaatatt gccatacgac
    10381 aaatagtacc taaagtttca gcaacataaa aatctgcatc ataagatttt tgacttaacc
    10441 aaattttaaa gtttttcttg ttaccagtta ttatacctac aataaagcaa gacatatatc
    10501 cacttccacc taattttgta gataattcat atgcaactac aactgaaata acagatatta
    10561 ttggtgcaaa atctttaaat attccataag gtttatcatt aactaatttc aaaagcagta
    10621 ttcctgtaat taaaccaact aaaactccga caataaccat tgtccccagt tcataaatat
    10681 tttcacctaa tgaaaattta tttgacaaaa ttacagccaa cactgctgat gttagtatag
    10741 ctcctgttgc atcattaaaa gctgattcac ttattacagt ttgttttacc ctatccttta
    10801 tctttacctg attaaatata ggtacaagag tggctgggtc tgttgatgct attatagttc
    10861 ctgctagtaa agcagtcatt gcacttatcc caaaagtaaa tcctattact tgttgcatta
    10921 taaaagcaga tatcacaact cctaaagtag ctaataagaa tacagatatc ttcacatttc
    10981 tcaatacttt taaacttatt tcttttccac ctaaatataa aataaatgca gaaccaaatg
    11041 taagtattag ttgattttct atttgaaatc cacgaatatc tataaatttt aaaaatgatg
    11101 gtcctattaa aatacctaca agtaaatata acactacatc tggaaccttt attatttcac
    11161 taagcttact acaaattatt ccagttatac ttacaatagc aaaaattatc aataaattat
    11221 tgctggcaat tgtgtgtata gatgcttcca tgtccgtctc tcctcccgat ttgcatacat
    11281 tatgcaatat acttattgtt ttactatata attatagcac acaaataaat gttatcaatc
    11341 atttttttta ggacatgcaa tttagctttc atttttgaca attaaataac gcttatataa
    11401 ttttgctatt ttttgctagt tattaaaagg ttgattttgt caagtttata gtatatatat
    11461 attaatattt tttatatcca tatcttttta gatatttttc gactttttcc cccattaaaa
    11521 taagtttaaa tttaacaata aaacatttca ttatatatat tttttaaaat gtaccatttt
    11581 caacattttc attaacttgg tctattcatt tttttcttat ctattctata tccaagcata
    11641 ttccctatat ttttacttac atgtaattct tgagctattt caagtttatt atcattgctt
    11701 tgttttatct tagaaatctc actttgtttt tcattttgtt tatcttgttt catagtttct
    11761 cctttcaaaa caatatcact ttttctgttt attacttatt atttcaaatt tctataattt
    11821 taatcaaaaa agggaaatat ctcaatataa tatagcttat tcaacaccat atttatatat
    11881 agaatttccc taattatttt attaatttaa tttttcaata accttatcta aattagaatt
    11941 tactttatct tcctttttcc aagaatttaa tgtataatgc gttccaaatg taaataaacc
    12001 tgaaactatt aatataaaat agtatacaaa cccactatat aagagtacag agtaccccaa
    12061 taattctttt ggaattatat tggagaacat agtaaaaaat gtaacctcat tagctccaac
    12121 atttcctggt gttggaattg gtgatatagc catatataaa aagacctgta atgtcattat
    12181 atgtacatat gaaactcctc ttaaatttga ggctttatac acacaataaa ctatactgaa
    12241 atatgcgatt aattgtaaca cagtaagtaa tatacttaaa actaagattc ttacattttt
    12301 aataaatatt tttatagaat aattataatc atcaatataa tgatttattc tatcacgttt
    12361 tgaatctaaa aatttaaatg ttttaaattt agataaaaaa ttaatcaaaa cttctgctat
    12421 catttttact tgttttggac taaatactat tagtagtcca cctaacaaca tacttacatt
    12481 cataatcatt ccaaaagtta tcaagacttt cacagaatgt acttgctcca tcagtaatga
    12541 cttatttagc aaaattaaaa ttccacaaaa tacggtaact gtactttgaa atactacagt
    12601 tttattagta actatagcca ctgatttact aaggcttaca tcatattttg taagtgcata
    12661 tatttgcatt ggttgactcc cagatgcaaa tggagtaact aagttatagt aaaatcccat
    12721 tgtagccatt ttaataccaa taaatttcac ttttgttttt tgaactgcat ttattatcaa
    12781 atgagttaca atagattcaa ttatcatata tactataatt gtcaatatgc caagaaatat
    12841 ataagtctta tttactagcc ttataatttt aggtattagt tttatatcta aagtagttaa
    12901 tactaaataa gtagtaatac atatcaaaaa taataaaaat ccatattgaa taaaatcttt
    12961 ttctcttttg gataattttc tcatttattt tctcctaaat tttttcatat cactatacat
    13021 agtatactac ttaacctatt atttgcaaga ctaaaaaaga taagtcttta tttgacataa
    13081 atacacctat aaatttttaa atatttttac tcctttagta gaaataattc tccatatcat
    13141 aaaatctaat atcaaagtaa gtatacttgc caaaataata tatacattta aaaacgaaat
    13201 tccaagtaat acatatatac ctccaagtat aattacataa gctaatgata ctaacattgt
    13261 aactatcata cttgcacttc tttttactac agccacctca tttttccaat caaggtttgg
    13321 gtataataaa tttgataata atcccatcaa tgctacaaac attgaaaaac ttacaatcaa
    13381 acagattgat acaataataa actgaatttc aaagtctaat cttatagata ctaatattag
    13441 acataaaata gataatgggg cattcaataa aaaattcatt aatacttttg accagaatat
    13501 ttctctttca tctattggag aagatttcag tatccataaa ttttttcctt caagagaaat
    13561 tgaacagtat gttgtacaat tcattactat tataaagaag aatactccca ataattgtat
    13621 ttttataaga ttaaaatcta tattcaattt cagtaactca cccactttat ctgctccaaa
    13681 taataatatt aaaattgtac ctactattag aaataacaaa cctgcagatg aatttaaaaa
    13741 gtatataaac gaagaagtat atctcttaaa ttcttttttt aataaagctt ttgaaggtct
    13801 tgaagttttt tgacccttaa attcataatt ttttgactta tatccttcac tcatcttagc
    13861 atttatatct ttaaattttt ttgcaaacag agttacaaac ataaaaaatg gtattatcga
    13921 gatggctata aatgctaaaa atgaaactat acttcctgtt ttaagagcat caacaaaata
    13981 atatatagga ggatatactt ttctaattgt ctctgaaata gacacactat tctttagcat
    14041 ttcaactgac atagaattaa gtcttgacat aagtagggta taaagcaaca tcaatataat
    14101 gctacctatg attaatacta aatttttgta ttttattctt gatgatatct gccctataaa
    14161 tagaaaaatt attgatgaag caactatcgg taataatggt aaagctaaaa atagcaatat
    14221 caaataaggg aaataagtta tacttacatc agaatttaaa aagtaaacca ctgcaggtat
    14281 aatcatacat attgaagaaa ataaatagtt tgctccaacc aacattaata tcttacttgc
    14341 tagtacagta gattctttta taggtaaact agtcaaaagg tctaaatctt ttgcttgaaa
    14401 tagatatgat gatgttttat ataatgatgt aacaatagtt gttaatgttg ataatccaaa
    14461 accaaatatc agtagcattt ccagttgatt tatttgcttt aagatatcaa ctaaagagag
    14521 acttaagctc gttacataaa aaattaatag acccgctatt ataacaactg aaagcatcat
    14581 tcccattatt ttttgttttt ctctaccatc agcttttttt aacgcattta atttaaattc
    14641 atttattata ttatttttta ttaatatact tagattgctc atattttatc attcctcact
    14701 ttagacacta tattgtataa aaaacatttt atttctctat taattccata aagatacttt
    14761 caagtgaatt acttccctta acttcttctg tagttccata agcaattata tttccatctt
    14821 ttattatggc aatcttatca caaatttttt cagcaacttc taaaacgtgt gttgagaaaa
    14881 atatacaacc acctttgtca caaaactccc tcataatttc cttcaatata aaggaagctt
    14941 ttgggtcaag acctacaaaa ggttcatcaa gaattaagat ttttgggctg tgtatcaaag
    15001 ccgaaattat agctaatttt tgtttcatac catgcgaata tgaagatatt aaatctccta
    15061 atgctttatt gagttcaaac ttatttgaat aatattttat taactcttct cttttatctt
    15121 tggcaacttc aaatatgtca gctataaaat taaggtattg tataccagtt aatgactcgt
    15181 ataaatctgg attatcaggt atatatgcca tttccttttt acattcaaca ggctgttttt
    15241 ttatagattt agaatttatt agtacttctc cctcttcaaa atcgtgtatt ccaacaattg
    15301 ctttaatagt agtagtttta cctgctccat tatgtcctat aaacccaaaa agctctccat
    15361 catttacatc aaatgagaca ctacttacta cttttttatt tttatatgat ttagatacat
    15421 tgattacttt taacataatt tccctccata ttatagtttt gatatttgtt atatataata
    15481 tataacaaat atcaaacaat tacaactttt atttgtttat tttagaaatc tataaaatgc
    15541 aaaggtatca gaaatataaa ggtataaata taattgatat ttactttcaa attacacata
    15601 attataaaag aatatatagt tcgatttgaa taaacaatgt ataataaaaa atagttgact
    15661 ataattatta aaatataagg agtaaaatat gaatacattt gaacaattaa aaataagttc
    15721 cactctaata gatggactca aaaaacaaga cataacttct ccaacagaag ttcagtcact
    15781 tgttataggg aatataattc aaaataagga tttattgatt aattcacaga ctggaacagg
    15841 aaaaacacta gcgtaccttt tacctatatt tgaaaaaatt gatacatcaa aaagagaaac
    15901 acaagctctt atacttgcac ctacgcatga attagtaatg cagattacaa accaggttga
    15961 attattggct aaaaatgcag aactctccgt tacttcttta gctttaattg gggaggtcaa
    16021 tatacaaaaa caaataaaaa atataaaagc agtaaaacca cacatagtaa ttggctcttg
    16081 tggaagagtt ttagacttga taaaacaaaa gaaactaaaa tcacataata taaaaactat
    16141 tgtcttagat gaagtggaca atctattgaa tggaaaaaat ataacttgta tagaagacat
    16201 aataagaaca acgttaagag atagacaaat tataggatgc tctgcaagtc ttactgatag
    16261 cactataaaa atttgtgata aacttatgaa ggagtttgaa ataataaaaa caaaggaaaa
    16321 atcacaaata aatcctaaca tcaatcactc atatttatta ggtgagataa gggataaatt
    16381 tacttttctt agaaaggcat tagcagctac aaatccaaaa aaagctattg tatttgtaaa
    16441 taatgaaaaa aatatagaag tcctagtatc aaaactaaat tatcataatt acaaagcaat
    16501 aggaattttt ggaaatatgg aaaaagaaga tagaaagaat gcaataaata aatttaaact
    16561 tggtaaagca aagattttaa ttacaactga tttatctgct cgtggactag atattgtgga
    16621 tgtaagtcat gtttttaact tggattttcc aaaaagtaaa aatgaatacc tgcatagatg
    16681 tggtcgaact gctagaggaa atcgaagtgg taacacaatc tcaataataa caaaaaaaga
    16741 attagatatt ataaaagatt tgcaaaaaga gttcaatata gtaattacac ctaaaacttt
    16801 acaaaatgga gaactaatag acattattaa ataatacaat aaatacaaaa atacaacaaa
    16861 tacaaaagag ctgtagttta tcatcacaat tgataataaa ttacagccct ttattttata
    16921 ttaaattaga attttaaata atacctatta tagtagccaa agttttatta taaataatat
    16981 tgccagaaca atcattacta cagaaacatg ttttttgtct tctgcctttt tagctccaaa
    17041 tatattataa aatatattta cgaaaacata agttaatata cctaaagtta aaccatcacc
    17101 tatactatat gttaatgcca tacaagcaat agtaacaaaa gctggaacac cttcagttat
    17161 attatcaaac tctatatcct taactgtacc aagcattaaa tatccaacat atattaaagc
    17221 tggtgctgta gcacatgatg gaattgctat aaatacagga gagaaaaaca ttgcagctaa
    17281 gaataaaatt ccaactgtta ttgctgtcca tccagttctt ccacctgcga taactcctgt
    17341 tgaactctca acataagttg taactgtaga tactccaagt cctgcaccaa ctgtagttgc
    17401 aaccgcatct gtaagtaagg ctctacctac attaggaaca ttcccttttt catctaacat
    17461 gtttgcttta gaacaaacac caactaatgt acctactgta tcaaaaaaat caacaaataa
    17521 aaatgtacaa actactacta aaaaaccacc tatatttgtt ggatgtagta catatcctaa
    17581 atctatttta cctgctattg gtgctaaact ttcgaattta aataatccac caggtaaata
    17641 tatacctaat ttttgtgcat actctggatt tataaaagca aatgcccaag caagtaatga
    17701 actcactact attccaaaaa gtatagaacc tttaactctt tttttatcta atacagcaat
    17761 aattattaat cctacacaag ttattattac tgctggtgta aatctaccca ttttgataag
    17821 agtggcttgg tctccaataa caattccact gttaactaga cctataagtg caataaatat
    17881 tcctatacca cctgtaacag ctaatttcat attttttggt atcgcattta caacagcctc
    17941 acgaactcca cttactgata atactataaa aataatacct tctacaaata ctgctgtaag
    18001 agctacttcc caaggaacac ccatttgtaa aactactgta tatgcaaaaa atgcattaag
    18061 acccatacct gatgctaaag caaaaggaag gttagcaact acacccatta aaatacatcc
    18121 aaatgctgct gctaaacaag tacctgtaac aagtgcacct gcaggcatgc ctgtctcaga
    18181 taaaatattt ggatttacag ctattatata agccatagtt aaaaaagtag ttactcctgc
    18241 aattatttcc ttcttcatgt cgacattttt attagtcaaa attggaaaaa gtttctgcat
    18301 agtactactg tttgttgttt gcataacaac acctcctatt aaattttaca aaaaaacgac
    18361 acagtagttg ataagctgag ccgtatcctt cataattcag ttaattaaat atttaattaa
    18421 ctaaataata gtatacatag tcagaatatt tacggtattc cggtagaaac ttatgaccca
    18481 tattgtcaaa attatatgtt atacagtaca aaacatgaat ttttctttac gaatattatt
    18541 ttaatttata taattaattt tgtcaatata tacgtatata ttgtattgat tttgtattaa
    18601 tattcgatta tattaaatat tgatttatta aattcaaatt ataattatat tctttacatt
    18661 ttaaaaaaat atatgatatt ttgatacaat ttatttatag tttggatata aagtttatgt
    18721 taagattata ctataataaa ttaataattt ttttatttgg aggaataagg tgaaagattt
    18781 aactacaggt catgagggaa agtccatatt cttttttgcc atgcctatgc ttattggtag
    18841 tttatttcaa caactataca atacagctga cagtataata gttggtagat ttattggaaa
    18901 agaagcaatg gcggcagtct ctggagctaa ccctataatg tttttattgg tggcagcgct
    18961 tatgggtgtt agtcttggat tttctatttt agtgtcacaa ttttatggct caggagattt
    19021 aaaaaaggta aaagctacta ttgatactac atatatactt ttatttattg gttctatatt
    19081 aataagtatt cttggaatag tatttggtgg cccaatgctt aagcttatga atacaccaga
    19141 atccgttttt gctcaatcaa aattgtatct tactataata tttagtggaa tattattttc
    19201 tgctggatat aattcagtaa gtgcaatact tagaggactt ggagattcag taactccact
    19261 ttattttctg ataatagcca caattctaaa tatagtttta gacttaactt ttattgtagt
    19321 gctaagaatg ggtgttgagg gcgttgcact tgccactata atggctcagg cagtatcatt
    19381 tataataagt ataatttatt taaataaaaa acatgaagtg cttaaattta aaatcaaagg
    19441 aattgtatat gataacaaaa tatttaaaga tggacttaga ttaggacttc caagtggagt
    19501 tcaacaaatg ttgttttcaa ttggaaatat ggctcttcaa tttttagtta atagttatgg
    19561 tacatctgct atggcagctt ttggtgctgg tcttaggata gaaaatttta taagcttacc
    19621 tattatgaat cttggttctg ctgtttctac ctttgttgct caaaacatag gtgctggaga
    19681 aaatgaaaga gttaaaaaag gcattcgaga atctataaaa atgaccttag ttttagcagt
    19741 tacagttatt gctttaattt tgctatttag ggaaaatcta attgctctat tcaatactga
    19801 taaagatgtc attaaaattg gctcttctta cttatttata ataggaccat tctttttatt
    19861 tattggaact tcttttgtac tttcaagtgc aatgaaaggt gctggtgatt ccatgtttgc
    19921 acttataagc tcaatagtat ctttatggct tggaagactt ccagcttctt atatgctttc
    19981 taaatttttt ggaacagacg gaatttggat gggtatccct tttggttgga ctttaggtct
    20041 tattgttaca gttatctact ataagaaagg acattggaaa actaaagcta ttgtaaatca
    20101 tagaatcaat gaataatctt tttataaaat gtattcacat tcattgtatt cacctccatt
    20161 atgatataat aaattatgga ggtgaatata aaaatgggta ttattcttaa gccaaaacaa
    20221 ttttatatga ctgttatagc taccataatt ctctacttct ctcttaatta cagtttcaac
    20281 ataaaatttt ctatatgctt atctttttta actatcttga tatgggctgt agactcagtt
    20341 gaaaaaactt ttgttgcatt gttttttgta attctagcgt ttatatttaa cattgcacca
    20401 ataaaggtta ttttacagtt tttatttaca gaaaattttt acataataat tcttgcatac
    20461 ataattacta atgcagttac aaaaacaggt gtcgcaaaaa ttatttctga gaagttaatt
    20521 ttaaatactg taaatacccc taaaaaaatg attcttttat cgtatatttt aggtatactt
    20581 ttaatatttt ttatcccaca accatttcca agggttattc ttgtatctgc tttttacaag
    20641 gagtttttaa aagaacaaca gataactgaa gattcaaaat ctatactttt atttagtata
    20701 tttacagcat ctacctttac atcaatgttt tttgtaaatg gagacactct tctaaattat
    20761 gttgtactag aacttggaaa ttgtaatata aattggggtc aatgggcttt ttatatgtct
    20821 gttccaacta taattacttg ttttataact tattttttat ttatctttgt ctttaaaaaa
    20881 gaattgcatt caataaaatt tatttctaat gaaaatcttg agggtaataa acttcatttt
    20941 tcatattcta atttaaaaaa agaatttaat ttgctaaaca aagagcaaaa acacgtattt
    21001 ttatgcctag gaataatgtt ttttatgttt ttaactcagt tcatacataa cataaacaca
    21061 ttaattataa tgtcaatttg tgtacttctt ttattactaa gaaaaatagt tggatttagt
    21121 actttaaaag aaataaattg gaaggtcctt atttttttta tagcagcatt ttcaattgga
    21181 ggagtgttaa agtactctgg agttgtagat ataatgggaa attatttgat aaagtttata
    21241 ccaaactctt cagaaattat ttcaatattg tttttgataa ctctcacaat aatcttgaat
    21301 atatgtcttg gaagtgctgt cactacatca tctgtagtga taccgttact tggaagttta
    21361 catatactaa aggaaaatag tgttacttta tgtctatttg tctacattat agtaagcata
    21421 cagtacatat taccatttca tcatgctaca ataatggttg gtcatggtga aaatctgtat
    21481 aatagcaagg ttattttcaa atacggttta actttgattc ctttaaccta ctttataata
    21541 atatgtataa cattcccttg gtggaaattt ataggactag aaatctaaaa aagatgaaaa
    21601 tatgaattaa cttaagataa taacgaaatt attaaaaaga aaattcatat tttcatcttt
    21661 ttatataagt tcttgtgaaa ttggacaaaa ctactctttt accataatac taaatattat
    21721 ttgttttact tccttttcca aaagtattct cccaatcctc tataaactta tctacactcc
    21781 aatcagttaa tggatgattc atcatagatt tacaaatatc atatggtact gtaacactat
    21841 gcaccccatg ttgcattaat tctataactt gttgtgcatt tttaaaactg gctgcaagta
    21901 cttttgtctc cattttataa gtatctatta tttttataag ttctgaaacc atagctactc
    21961 catcaccaga tatattatca agcctattta cataaggtgc aatataattt gctccagcct
    22021 ttgcagctaa aaaaccttga tgagcagtga atattgcagt agcagttatt tttacacctt
    22081 ttctgtgaag gtcttttata gctcttaaac catcttgtgt tacaggtatt tttacatata
    22141 tattttttct caaactactt atatataatg cttcttctaa tatttcttca tactttgtac
    22201 ttaacacttg agcatgtata ggaatatcct cacctataat ctcaccaatt tcatttataa
    22261 gttgcttaaa attctttttt tcttttgaaa caatacttgg atttgtagtt acaccatcta
    22321 ttggtaaaca agtacataac tccttaatct cctccacatt acctgtatct aagattagtt
    22381 gcattaaaat atcccccttt aatctttctt tattcttatt atatattgat ttggtattat
    22441 tttcaacatt ttgcttattg ttttttattt tttattattg ttttactttt ccttcttagt
    22501 tttataattt ttttatttac taaattctaa atatatagtt agaaaaaaca tactttttat
    22561 attaaattaa ttttgtattt catgttaaaa tagttgatat attgtatttt atcttataat
    22621 atttactata atactatatt gcgaaaagag gtagaaaatg tttgcagaag aaagaatcca
    22681 agctatatta aatatcctaa aaaaagaagg tagagttact gtcaaagagc tcagttctaa
    22741 atttaatgtt acagaagatt gtataagaaa agatttaaaa aatatagaaa agatttcttc
    22801 aataagaaga atttatggag gagctgtact agctagagaa acactagaga atcaggatac
    22861 aaaagacaga aaagaaatta atattccaac aaagaaaata atagcagaaa aagcatttaa
    22921 tttaattgaa gatagagaaa ctatattttt agatatctct acaattaaca tcttgcttgc
    22981 aaagttgtta gctgaaagta ataaaaaagt aacacttgtt acaaatatgt tggatatact
    23041 aaatgtagtt acttcaaaac caaataattt aaatataatt tccactggag gtttattaaa
    23101 tctcagttta gacggttttg tcggtactcc aactatagag tttatatcga aatataagtt
    23161 tgataagact tttatgggaa gttgtggagt agatgtattc aactcttcac ttacaacttt
    23221 tgaaattgaa gatggtctta cgaagaaggc tataataaat tcaagtaaaa aagtatttat
    23281 agttatggaa gataaaaagt ttaaatttga tggaaatttc aagtttgctc atttagaaga
    23341 tattagttct ataattacag aaaaaacgcc tactcctgat atagtagata ttttatcaga
    23401 atttaatgta aatgttttat aagtttaatt atatatttta taggatttct tataaatata
    23461 aatttttatt tgataactat tcttaaaaac atatttctat aatatttatt ttatccttag
    23521 tatctatttt ttaaaatcta gttctataac atctacttta tccttatgtc tatttataaa
    23581 actaatttga aatagacttt ctaaatctaa tacagttatt tttagaaagt ctatttcctt
    23641 aaataaacta tttaatatta ctggctactt tttatatgaa tacaataatt tgttattcat
    23701 aaataaaagc ttatttcatt tcattcttca tttgcttctc taattcttta gaaaatttct
    23761 tttgttcata tctttccatc atctcatctt ttttcatttc taagtttacc atagcacctt
    23821 gtgcatcatc tttcaaatct tcagctgtat ttttcataac ataagctgtc tttttaacac
    23881 cttcttttaa atcttctttc atatttttca tatctctttt taatctatcc atcaaaacta
    23941 cctcctctgt aaatataata cttcctatat ttatttttcc caaagtacat atatttattt
    24001 gtaatatcaa ttataatttt taagtcttaa atatagttta aactatctaa atctatacat
    24061 ttcaataaat taaatatttt ttatttcaaa ataaaaataa cactaagcat agattatatg
    24121 ctcggtgtta ttttttaaat tcatagtaac ttaattgttg ggttactata atgatgactt
    24181 atatggagga tgtaaggaaa tctcatcatt atagttggtg tattttatgg ttttaagctt
    24241 ctttatattt atataataca gtttcattat gaattttttg tgattttaaa atgaactatt
    24301 attgaaagtt atatattctt tataataagt aattaatttt taaattctac tgtgaatact
    24361 acagagtttt ctttgttttt tatgctataa tcaaacccat gacttttaaa aatttggctg
    24421 actatataaa gaccaagtcc acttcctcca gtttttcttg aacgagattt ttctattcta
    24481 taaaatggat taaatatttc ttctaaataa cgtttctcga tagttacacc agtattttca
    24541 atttctaaaa ccactctttg attagaagtc tttttactta ttcgtttatt tttatcatag
    24601 agtctaatta taagctctga ttcttcagga gaatatttta tggcattatt tattatatta
    24661 ttgattgcct tagttattct ctcttggtct gctttaattt ccaaattttc ttctattttt
    24721 aaaatagttt tcatatgttt ttcttctatt aaaaatactt gtctctttac aagtctattt
    24781 aataattcac ttatatttat tgataccaat ttcaaatctt tttcaagtat ttctgatttt
    24841 gaaacctcta tcatttcatt tactaaatct tttaattctt gtgtacactc atacgatttt
    24901 ttcagataag tatccctatc cttatactta cctacactat aaatcatacc ttcaatttga
    24961 ccacttatta tggttattgg agtttttagt tcatgtgata ttgtagcaac aaaatccttc
    25021 cttctatatt cctgttctct ctcactctct attatgttta taagaggctt tgttattaca
    25081 attgaatata tatatgctcc aataatcgct atcaatattg ctattgatat gatgtatggc
    25141 attagttttc ttataacttc gtttgcttcg tcaattggtt gtaatggcat aacgagttct
    25201 aaagtatatg gaccatcttt tgcatcttta gtatatatag gtatagaagt tctatactca
    25261 tcctcaagac tattaatcat gtacttacta tatcttaaaa taactacttc attcttacca
    25321 tatacaattt taccttggtt atcttttaat aaaatagcca aattttggtc tttagccata
    25381 taataaagtc tttcttctaa agtatatgta tcgaaatgaa ttgaactatc tactaaagat
    25441 ttcaaacttt cttgaagaga ctcaatttta tactcatgat aatatgatgg caataaaaaa
    25501 tataaaatta gatatattat taaagctaat gctattaata atgatgtcgt tattgaaaat
    25561 aacttatact ttatgcttaa cttttcccac ttatcaaata tccttctcaa gtgtatatcc
    25621 tattcctttt acagttttaa tatatggtaa tgatattttt tttcttatat tttttatatg
    25681 tgcatcaaca atcctagtat ctccataata gtcataaccc catatactat ccaaaagacc
    25741 ttccctagtt ataacttgtg gatacttttc tatcaaagct tttaatatat taaactcttt
    25801 tagtgtaagt tctataggtt ctccatctat ctctgcaata tatgtgttta aatctaattt
    25861 taatttttca aaaactataa atttgtcatt tatagtcttg ttacttcgcc ttaaaattgc
    25921 ttctactctt tttataagaa gattaaatga aaatggtttt gttatataat catcacattc
    25981 taagtcaaac cctttaagtt ggtctccttc atcatttaaa gcagttaaaa atataattgg
    26041 aacgcttgat gactttctta tcattttaca aactccataa ccatctaagt ttggcatcat
    26101 tatatctaat attactaaat cataacttcc ttgcttaaac ttttgtatac cttccaaccc
    26161 atcatttgct gtatcaactt gataaccttc tgcacttaaa aattctgata ttaactcttg
    26221 tatatttgaa tcatcttcaa ttacaagtat tgacgaattc attctatcaa tcctttctat
    26281 tttatttaaa atttcgtata ttacttatat tttatcttat tgttgtgaat tttacatgaa
    26341 aaaagagcta tcttaatttg taaattaatc cttttaattt aaagatagct cttttggata
    26401 cattttattt aatttattaa tctaatctct cttatatgcc ttgaagtttt taagtctaag
    26461 tgcatttgat acgactgaaa ctgaacttaa gctcattgct gctgctgcaa tcattgggtt
    26521 taataaaggt cctccaaata catataatat tcctgctgct acaggtatac caattgtatt
    26581 atatccaaat gcccaaaata ggttttgttt tatatttttt atagtttcat gactaagttt
    26641 aattgctgtt ggaacatcaa ttaaatcact cttcataagt actatatccg cagattcaat
    26701 ggctacatcc gttccacttc ctattgctat ccctatatct gcttttgcaa gagctggggc
    26761 atcatttatt ccatccccta ccattgcaac aaactttcct tgattttgta gtttttcaac
    26821 ttcttttgac ttatcttctg gtaaaacctc tgccaaaacc atatctatac ctacttgatt
    26881 tgctatagca tttgcagttt tcgcattatc tccagttacc attgcaactt ttattcccat
    26941 atcatgaagt atttctattg cttttttact actttctttg actacatctg caactgctat
    27001 tatacctgat aaatttccat ctacagctat atacataggt gttttacctt ggcttgccaa
    27061 tatatttgat ttttcttcta aatccccaag ctttatatta ttgtcattca taagctttct
    27121 atttccaagt aatatacttt catcattaat agtaacttgt ataccagcac ctggtatagc
    27181 tttaaaatta tcaacttttt caaattttat attcttctct tctccatact taactattgc
    27241 ttctccaaga ggatgttctg aacctttttc tgcacttgaa gcaatcttga taagatattc
    27301 ttcttttaca ttattattta atactatatc tgttactttt ggctttcctt ctgttatagt
    27361 acctgtttta tcaaatatca ctgtatttac tttatgtgca gattctaatg cctctccacc
    27421 ttttatcaag attccatttt ctgcgccctt tccagtccca accattatag cagttggtgt
    27481 tgctaatcct aatgcacaag gacaagcaat tacaagtact gatataaata tagtaagtac
    27541 aaatactata tcttttcctc ctattaaaaa ccacaataat gatgcaacta cagctattgc
    27601 aattactatt ggtacaaaat atccagatac agtatcggca agtttagcaa taggtgcttt
    27661 tgtaccttgt gcatcttcaa ctaactttat tatttgggca agagcagtat ctccaccaat
    27721 tttttcagcc ttaaacttaa taacaccatt tttattaata ctagctcctg tcaccttact
    27781 tccaacattc ttttctactg gtatactttc acctgtaagc attgattcat caactgatgt
    27841 atatccttct attacaactc catccacggg tattttagtt cctggtttta ctaatagtat
    27901 atctcctatc tctacttctt ctataggagt ttcaacttct ttaccatcaa ctaacactat
    27961 tgcagtttta ggttgtagcc ccataagctt tttaattgct tctgatgttt ttccttttga
    28021 ttttgattct aaatatttac caagtaagat aagtgctatt attattcctg cactttcata
    28081 atacaactga tgatggtgca taccttgaat ttgtccattg gctatttgta gtgtcgtata
    28141 tagactatat aaaaatgcgg ctaatgttcc tattgcaact aaagaatcca tattagggct
    28201 taaagaaaaa agtgatttaa acccatttat ataaaattta taaccagcta tcattactgg
    28261 tattactaaa attaactgaa ttaatgcata attaaaagta tttgtcatag gatttataat
    28321 ttctggcaaa ggccatggcc ctataggctt tattatcata ggtcccattg ctatataaaa
    28381 cagaggtact gcaaatacta ttgcaactat aaatttaaca aataaagact tcatttctct
    28441 ttcttttctc aatttatctt catccacatc aaccttattt cttacctctt ctattggttt
    28501 atatccagct ttttcaatag ctgcttttat ttgagataat tttacttttg atgggtcata
    28561 gtctatatta gctttatctg ttgcaatatt cacactaata ctttctactc catccaattt
    28621 ttttaccact ctctctacag cttttgcaca agctgcacat gtcattccat caattttcat
    28681 atcaattttt ttattacttt cttcctttat aattccatat cctgcttttt ctacaacctg
    28741 ctttatatca tcaaaattaa ccttagaatt atcatattct attttaagtt tttcagtagc
    28801 tatatttaca ctttggtcat atactccatc catcttctta gttactctct ctactgcctt
    28861 tgcacaagct gcacatgtca tacctgtaat tttataactt tctaccactt tatttgaact
    28921 cataataaaa tcttcctttc tttcaatata ttttcagcta atttgtaacg ttttattttg
    28981 atatgtaata ttgataaatt acttatttag aaatctatat ttttattata ccccctatag
    29041 gtatattaaa tcaatatttt tttaataaat aaatgtatta gttatattta tttgtattta
    29101 atagaaaagt atactcataa ttaaatgtat atataaaaat agagcatcta aattgtttaa
    29161 tgcttataca atttagatgc tctatttatt atattttatt taaaatttat tctttacatg
    29221 cttcaaaaaa ctctgcttct gtttccttta tttcaagctc attgtctatt attccaacag
    29281 cttctttttt aaatgctcta cactgaccta tacaaccagt ctttacattt tcttctccaa
    29341 ccaaagtttt tagcttattt acatccacat ttgaacagtt tggacatact cttatcatat
    29401 ttaagttcct cctaattaat gtctaattaa tacttttata cccaaatata aactttataa
    29461 aagttttttt aatataaatt attaccatat ataccattta tatcctattg cgagtattac
    29521 atattaattt tatatattat taatactaca tgtacggtgg tatctgttgt tttctcacta
    29581 tttccaattc cttaatttct aaagacttaa tcacatttac tttatagttt tctttagact
    29641 ttatatacaa aacatcttct atctttttac cttcaataaa tttatgagac cacttaagaa
    29701 gttcttcaaa attacaaact tcttctttta caaaagtatc actttcactt gcaaaatatt
    29761 taattattat tttggttact tccaacatat atcatccttt actcttttat taatcttttt
    29821 atctattaaa gttattattt gtctaaaaaa tttttttaaa cagaataatt ttcagatgca
    29881 aaactaacag ttttatccaa tttaaactat attaatacaa tttaatatat tcctccttgt
    29941 acctaataat atattgtgct ataattaata agttatttta atcgaaggga gcaacaaaaa
    30001 tgtcacaaaa acataaaatt ataaatatcg cagttatagc ccacgttgac gctggaaaat
    30061 caacattggt tgatgctttc ctttctcaaa gcggtgtttt tagaaagaac gaagtagtta
    30121 aagactgcgt tatggacagt aacgaccttg aaaaagaaag aggcataact atatattcaa
    30181 aaaactgtgc aataaactat gaagattaca aaataaacat agttgatact ccaggacaca
    30241 gtgacttttc ttctgaagtt gaacgtgtta tgaaaactgt tgacacagtt attctattag
    30301 ttgatgctag tgaaggccca atgcctcaaa ctagattcgt tttacaaaaa tctttagagt
    30361 tcggtttaaa accaatatta tttataaaca agattgataa aaaagaccag agagcggaag
    30421 aagtagttaa tgaagttttc gatttatttg tagacttaaa tgcaacagat gagcaatgcg
    30481 aatttcctat aatatatggt attgctaaac aaggtattgc taaacttgaa atggatgatg
    30541 atagtgaaga cctttctcct ctatttaaaa ctattgtaaa tcacgttgaa gcttatccta
    30601 attacgataa tgaacctcta cagttccaaa tatcagctct tgcatatgat gattatgtag
    30661 gtagacttgg tataggtaga atttacaaag gtactcttaa aaacaataca caagttgcta
    30721 tatgtagaga agattctgtt gtatctaaag gaaaagtatc aaaactttct gtgtatgaag
    30781 gtttaaaaca agttgaagtt gatgaagcta ctagtggaga aatagttgtt atagctggta
    30841 ttcctgatat atctataggt gaaactatat gcgatttaga tagtccacta cctatggaaa
    30901 tgataaaaat agaagagcct actctttcta tgaacttctt agtaaacgac tctccattcg
    30961 ttggaaaaag tggaaaattc gttacaacta gacatttgaa agatagactt gaaaaagaac
    31021 ttgaagtaaa tgttggtctt aaagttgaac ctcttgatac tactgatgga tacaaagttt
    31081 ctggacgtgg agagcttcac ttatctatac tacttgaaaa tatgagacgt gaaggttatg
    31141 aagttggtgt ttctaaacct gaagttttaa tgcataaaga agatggaaaa ctaatggaac
    31201 caatagaaag agttgttgta aactgtcctg aagtttactc tggtactatt ataaatgaat
    31261 taaacatgag aaaaggtatg atggagtcta tgtcaataga aggagactat gtaaaaatag
    31321 agttcttagc acctactcgt ggtcttttag gatatcgaag tgaatttata aacgctactc
    31381 gtggagaagg tactttagtt cgttcatttg aaaaatttga agaatttaaa ggagaaatac
    31441 cttcaagagg aaatggtgtt ttaatagcac aaggacctgg tgttactatg gggtattctc
    31501 ttaatgcctt aagtgataga gctgtaatgt ttgtagaccc tggtgtagaa gtttacgaag
    31561 gtatgataat tggtatgaat tccagaaaag atgatatggt agtcaatcct tgtaaaaaca
    31621 agaaaatgag taacgtacgt gcttctggtt cagatgatgc tataaaatta tctcctccta
    31681 gaatatttac tcttgaagaa gctctagagt ttatagaaga tgatgaatta gttgaaatta
    31741 cacctgattc tataagactt agaaaaagat tcttaaatga acatgataga ttaagatata
    31801 acaaatctag acaaggtaaa taaaacgtac atttacctct aattaacaaa atagccatat
    31861 agtactgaaa aattatttca gtttatatgg ctatttttat ttgaaattta tattattcaa
    31921 catttatata attagctgct tgaacggctg caatagctcc atctgatgct gctgttatta
    31981 tttgacgtaa aaacttagtt ctactatctc ctgctacata tacaccttct actgatgttg
    32041 tacaagactc atctgaaatt atatatccac cttcatccaa atcaagaaca ttttcaaaca
    32101 ttttattatt aggtttaaga cctatagcaa taaaaatacc actaacatct atagttcttt
    32161 tttcttcagt ctttaagttt tttacttcta ttttcgatac agtcttttct ccttctattt
    32221 tttctacacc atgactgtaa agtatctcaa tattctctct tgctttcaca gatttctcca
    32281 acacttcttc acctctaaaa ctatctcttc tgtgaattaa atacactttt gtacaattat
    32341 tagctaaaaa taaagcatct tctagtgcag tatttcctcc acctactata gcaacttctt
    32401 tatctttaaa aaaggctcca tcacatgttg cacagtaaga tactcctcta cctgtaaatt
    32461 cttgttcccc tgcacaacct aatttacgtc tttcaactcc atttgcaaga ataacagcct
    32521 ttgctttatg ttcacctgaa gaagttttta caacctttac ttttccctct aaatttatct
    32581 cttcaacctc atcaaactga atatcaacac cttgagcaac tgcttgattg tatatattat
    32641 tagaaaattc taccccagaa atcttttgaa ctgctggata attttctacc tcagaggtac
    32701 ttgcaacttg acctccataa atattttttt caaatactgt aacgcttaac cctgctctca
    32761 tagcataaat tgctgaagtt aaacctgctg gtccagcacc aattacaatg atatctacca
    32821 taacgtttac ctctctttat attattattt cttatatatt attctcatca ttcttatact
    32881 ttactattat tatccatata tactataaac aaaacattat tttttattaa ttaactttat
    32941 tttacatata tataaaaaaa ctgcaaataa aaattaactt ttatttacag ttctcactta
    33001 tttatataat tcaaaacctt attggttatc atttacagtg tcttctaata tattgctttc
    33061 tgatatatat gatagaattg aaagtccata cataaccaaa actaatgctg ctgttataag
    33121 tactattccc atatttaata cctccttttg tttacagtat actattatta tgtgaaatat
    33181 ttatgaattt aatttgaata tatatgtaat ttcacactaa caatttcttc aaattaaaca
    33241 ttattaacta tatacttttg ttgaaccaat tatgattaat agtttaaata ttagcactat
    33301 ttacttatat ttatatgata taccatataa ttacattttt caaattaaag ttttgtaaac
    33361 tttttttgta atatagtgta gtataaaatt gtaatattac agatatttaa tagttatctt
    33421 ttaattactt tcattaaaaa cagcttcatc actatgaaaa tctaggtttt taaactttta
    33481 aaaaagttaa aaaaatattt ttctaatact caatttgatt acaatttttt tacaatttaa
    33541 aaaatatttt ttccaaattt ttatattaat acttgacttt gtctgtttta taaactagaa
    33601 taattaataa tattaagaat attgaaaggc attgattagg aagagtaaat ctgaatcgat
    33661 taccagagaa ggaaactact agctgaaatg tttccctaat tagaaggatt gaaaactacc
    33721 taggagcttc tatccgaagt tatcttaatg attttagtag gaatagacgt ttttattact
    33781 tgcgttaaag tatcaagtgg attttttaaa atcaatttgg gtggaaccgc gggaaacaga
    33841 ttctcgtccc ttttttaggg atgagggtct ttttttatta cctaaattca gtttttaaaa
    33901 tattctgtat ctaatttaat tagctaatta aaaatttaaa atatatggag gattataaaa
    33961 aatgtattat tcaagtacga gaggcaccaa agaaaaagta actgcatcac aagcaataat
    34021 aaaaggaata tcaaatgatg gtggtcttta tgttccaagt gaatttccca atgtaaaaaa
    34081 tgaacttata aatttagtaa atttaacgta ttctcagata gcattttttg tacttagtaa
    34141 atttttatgt gattttactg aagatgaaat taaaaattgt atagaaaatg catatgatga
    34201 aaagtttgat tgtagtagta tagctccatt aaataaagta aatgatactt atttcttaga
    34261 actatatcac ggtccaactt tagcatttaa agatatggca cttactataa tgcctcatct
    34321 tcttaaaaca tctataaaga aagataattt agagaaagat gttgtgattc ttactgctac
    34381 atctggagat acaggtaaag ctgcacttga gggatttaaa gatatagata aaataaagat
    34441 aattgtattc ttcccagaag atggtgtaag cccagtacaa aaacttcaaa tgaaaactca
    34501 aactggaaaa aatacatatg tagttggtat aaaaggaaat tttgatgatg cacaatcagg
    34561 tgtaaaaaag attttttctg ataaagaatt taatcaaaaa ctattggata ataattatat
    34621 attatcttct gcaaattcaa ttaatatagg aagacttctt ccacaagttg catactattt
    34681 ttattcatat atgaaattag ttagcaatag tgatataaat ttaaatgata aaataaattt
    34741 tgttgtccca actggtaatt ttggtaatat tctagctgga tattatgcca aacaaatggg
    34801 tcttccaata aacaaattaa tatgtgcatc aaatgataat aatgttcttt atgatttctt
    34861 taaaactggt gtatatgata aaaatagaac attgaaatta actacttctc cttctatgga
    34921 tatattaatt tcaagtaatt tagaacgatt actgtttgaa atatcaaata gaaatactga
    34981 tattgtaaat aagcttttat cagaccttag tgataaagga gtctacaaaa taagtgatga
    35041 tatggaaaaa aatttagcct cattctatgg agaatattca aatgaagaag aagttaaaag
    35101 cacgataaac aatgtgttta aaaattataa ttatttgata gatactcata ctgctgttgc
    35161 atacaattgt tatgaaaaat ataaaaaaga aacttctgat aacacaaaaa ctgttattgt
    35221 aagtactgca agtccattca agttttctga agatgttcta aagtctatag attgtgattt
    35281 taaagacctt gatgactttg ctataattga tagattatca agtatttcta aaatagatat
    35341 tccaaaacct attaaaaatc ttaaaaatgc agaaatacta cataaagata tttatgaaaa
    35401 agatgaatta aaactagcta taaaaaaatt cttaaaggta taggtgatta ttatgttaga
    35461 gattatagtt cctgcaacaa gtgctaatat aggtccagga tttgattgtc ttggaattgc
    35521 gttaaatata tacaataaat tttatgttga agaaattgaa agtggtcttg aaatagaagg
    35581 ttgtgaagat gcttacaaaa acgaaaacaa cttagtttat acatctatga agtacttttt
    35641 tgatagagtt aaaccagaaa aaatacctgc tggtatcaaa ataaaaatcc aaagtgaagt
    35701 acctatatgt agaggtcttg gcagtagtgc ctcttgtata gtagctggag ttatagctgc
    35761 aaatgctcta tcaggtgcta atttagataa aaatcaatta ctaaatatag cttcagaaat
    35821 agaaggtcac ccagataatg ttgctcctgc tattttagga aatatgattg tatctgttac
    35881 tgataatgag aacatacatt atgatattat aaaaattcct gaagaactta aattttgtgc
    35941 aatgatacct aattttaagt tatcaacaga aaaagctaga ggtgttttac caaaggaaat
    36001 accatattct gatggggtat tcaatgttag tagagttgct ttactaatat ctgccttact
    36061 aaacaaaaac tttgacctac ttaaagtagc ttgtcaagac aaattgcatc aagattatag
    36121 aggaactcta attgagaact acaatgatat tgttgaaaaa tctgaacaat taaatagtat
    36181 tggagtattt ttaagtggag ctggacctac tataatgtct ttaataaaag aaaatgatga
    36241 tagttttgtg gataatatga aaaattacct acaaaaacta aaatctgatt gggaaataaa
    36301 agagttatgt tgcgattcta atggagctgt tttaaatata atataattat cgtcttctat
    36361 acaaaatata actactcttt tattataatt tgtagtataa taattaggac taggtaataa
    36421 tattaagtat tataatctag ttctttaaac atgtttacat tgaggaggga ttatcataaa
    36481 agagttaata attagagatt tagttgcaaa agttcctata attcaaggtg gaatgggcgt
    36541 tggtatatct aggtcatcac tagctggtgc agttgctaag cttggtggtg ttggtgtaat
    36601 ttctggagtt caaattggat atgatgagga agattttgaa actaatacta taaatgcaaa
    36661 tttaagagct ataaaaaaac atatttctaa ggccaaagaa atctcaaatg gtggtattat
    36721 tggtattaat tttatggtag ctatgaaaga atatgaaaca tacgtaaagg aagctgttaa
    36781 agctggtgta gaccttataa tatctggagc tggattacct aataagctac catcattagt
    36841 aaagggaagt aatgtaaaaa tagcacccat agtttcaact gcaaaagctg ctaatgtaat
    36901 tttaaaaatg tgggatagaa aagagaaaac tactgctgac ttaatagttg ttgaaggtcc
    36961 aaaagctggt ggtcaccttg gatactctaa cgaggaactt gataacatag attctataga
    37021 ctatgataag gaatttgttg aaattttaaa ggttgcaaat acttatggag aaaaatttgg
    37081 tagaaacata ccagtagttg ctgctggtgg tataacttct agtagtgatg ttaaaaaata
    37141 tatagatatg ggtgcaagtg gtgtacaagt tggtacaaga tttgttgcta cttacgaatg
    37201 tgatgcccat gagaacttta aaatggcata cataaatgct agtgaagaag atgttcatat
    37261 agttaaaagt cctgtaggtc ttcctggacg cgccataaga aacaaattta tagaagaagt
    37321 taaaataaat cgtccagaaa taaagaagtg ctataattgt ttgattcctt gtaatccaaa
    37381 agaaactcct tactgtattt ctcaagctct aatcaatgca gttaaaggag atgttgaaaa
    37441 ttcactttta ttttgtggaa atgatgccta taaaattgat aaattaagta ctgttgaaga
    37501 tgttatcaat gaattgattt ctgaattata atttaaagaa aactaaatta agattttatc
    37561 aagctaagga gtttaaatac gttatttatt aatctttata aacatattta tgtccttagc
    37621 ttttttgtgt caatttcctt ttattgaaat tttaatttaa ttagagatag tattaaccct
    37681 tataactaat cttcttttac aagtacattg gttatttcag ctatatataa agtatgataa
    37741 tctttttgtg gataccatct tccatctata ccttcagcaa taaaacattg gggttcaagt
    37801 ttctgactat acattttttt gcatataata gccattttag cttccttaaa ataaggtgta
    37861 tcatttaagt gttctatatt aaatccaatc tgtgatatct tatcctcttc tctaccagat
    37921 acttttccac aatacgaaag ctctttacga aaatcttcat caaaaaatgt aagagaaaat
    37981 ttatctgtat tatctataaa ttccttagta taacgctgtg gtcttattac tacaaaagca
    38041 acatcttttc cccacataac tccaagccct ccccagctag cagtcattgt attcacttta
    38101 ccttcatttt ctgctgttat aagtgtccaa tctttaccta tcaatccaaa tggattattt
    38161 ttaatctctt ctgccaaaat ttctttaaaa tcactcatat ctctaataac ctctcattct
    38221 cttatattta tattcctttt attttcatga taaattataa atgaagtcta gttttgaaaa
    38281 taaaatactt ttttaaatat attattgcaa ataagtaaat atatatatac actcttattt
    38341 tttaatatat ttaataattt cactcagaat atatatattc tttactcaaa ttaaatataa
    38401 cttatatact ttatgtgtaa attatggtaa aaatattatt taatcaaatc aaaacttgat
    38461 ttatatacct ggaaaaggta ttatattaaa gagtgcttaa aatacgcatt tcataaatag
    38521 ctatatataa aataataaat aaggagagtg atgggcaatg gatactagtc cgttgcggag
    38581 agaatttttt acattttcat cacttaataa tatctaaaat caaaactaat acatatattc
    38641 agttatataa attagttaat taatagatac tattaaatga tgagatttat ataaaactga
    38701 ataaaggatg tgttgccatg ataagatatt acaaaactat agattcaaaa ttagagaaac
    38761 ttagtttttt tgaagatggc tgttggataa atcttgttga acctaatcat agtgaaatca
    38821 acgaaatttc taatttatta aatatagatg tagaaagcat agaatctgca ctagatgaag
    38881 aagaacgctc aagaatagat gttgaagaca atcatactct tatacttata gatataccag
    38941 tagacgaaag tgactctaat tcttctcatt atactacaat acccttaggt attatactaa
    39001 ctgaagaagc tattgtaaca gtttgtgatg cacaaactaa gattttaaat gactttatag
    39061 ttggtcatat taaagatttt tttacgttta aaaagactcg ctttttgctt caaattcttc
    39121 acaaaaatgc agcttattac ttgcattact taagaaaaat aaataaaatg acaatcataa
    39181 tagagcgaga aatttacaaa tcaatgaaaa acaaagaatt ggttcaatta ttggaattag
    39241 aaaaatcttt ggtatacttc tctacctcac taaaatctaa tgaacttgtt ttaaacaaaa
    39301 tggttagaac cgctggtata aagaagtatc cagatgatga agacctatta gaagatgtta
    39361 tagttgaaaa tagacaggct cttgatatgg ctaaaatata tggagatata ttgagtagaa
    39421 ttatggatgc tttcagtgca attataagta ataatcagaa taatgttatg caaattttaa
    39481 cagtagttac actaattttc tcaataccta caataatatc aggattcttt ggtatgaatg
    39541 tcatcaacat gccattttct aataacccaa acggattttg gataatactt cttattacct
    39601 ctataatatg tatagtgatt acatttttca tgtcaagaaa taagctatta taaaatatta
    39661 ataaaaaagc cattagaatt aattgattta catttatcct aatggctttt atatatttaa
    39721 atctatataa tcttataata ctttttaact atcatgttct tcatctataa tcatttcagt
    39781 ttcaagccct tctagcattg aatctaaact ttcttttata tttagtatat aaattggtac
    39841 atactcttct tcatctatta cctcttcttg caacttaaat ggaggaatta atacttcatc
    39901 aaagtctata tttaaattag gaaagccttc tactatctct tcacaattat cgtactcttc
    39961 atttgccaaa gaaacgtaca tatctaggct ctttttataa taaagacctg caagcatata
    40021 ctcacacttc ttacttccat atttaatacc ttctttataa tatttctcag cttctgcgtc
    40081 atcatttaat tttaaataaa tttgacctaa attatatatt gattcaacac aaccttgtgc
    40141 tctagccttt tcataccaaa atttagaatt tacataatct ttatagaaca tatcataaat
    40201 taatcctacc atatgttgag catacacatt attttcattg gcaggtgtat caaacatcat
    40261 tttagactct tccaatttac cttctctaaa ataaattcta cctagatgta tacgagcatt
    40321 catatggttt ttgctacttg ccatttcaaa atactttcta gcattttttg tatttcctaa
    40381 gctctcatat atacacccca atctataact agacctcgta tctccatttt cagatgcttt
    40441 cttataccaa cttatggctt cttcaatatt atttaaatct tcatagatat ttcctaattt
    40501 gatttgacaa gatacattat ttggaatcct cgaataatac gaaatcgctt tttctatatc
    40561 ttgattctga taatataaat cccctagatt ttcaagggaa cttttgcatc caacagctat
    40621 agcatcctca taatatttaa tagcattttc ataatctttt tcttcaaaat atatacctgc
    40681 cagattattt tttgcctctg ttatatcatc ttcagcagcc attttataat aagtttttgc
    40741 cttctctatc tcattttctc tattatataa attagcaagt ctatacttag aaagtgtatg
    40801 atttttttct attgctttct cataataata aattgcatct cccagctctt cttttctatc
    40861 atatacatat gcaagcctat actcagactt cacatcatct ctatcagcac tctttttata
    40921 atacttctct gcatcttcta aattatcatt tatttccata atcataccca agttaaagca
    40981 acctttcata tgacctgact tgtacaactg tttatataaa cttactgttg atttattatc
    41041 tttctttttt ccatttaata ttgctaaatt atattttgca tcatcatcta aaagcacaga
    41101 acctttttta tagtattcat atgcttcatc atctttctcc aaaaaagtat ataatacccc
    41161 taaattaaaa caagctttac ctaaattctt gtctgctgct gtttttaacc atttttcaca
    41221 ccttacaaaa tctttcattt taaaatggca tacacctaaa ttattttgtg cttgtaaata
    41281 acctaaattt gctatctttt cataccaata tatagcatat tcatagccat ctaacttata
    41341 gtacatatta cctaaatcaa aagcagcatc ttcacttcca cttttatatg ccattgaata
    41401 ccacttttct gcttctttaa attgtttttt actttcatat atatttccta aagtatattg
    41461 agattttacg taattatcca atgcagcact cttatacaac tctattgcgc tttccatctt
    41521 acccatcttt tcaaggaggg cacccttagt atgtacgact ttcgggtcat tagatatatt
    41581 ttttattttt tttatagaaa attttgtatt tttcattatt cgctacctac ccattttata
    41641 aaatatattc tctcaaacat tattatacat tataatctac aattaatgct ataatattga
    41701 atttttacct tttgtcacta tattgtaaca ttaaatttta aattttataa tcattagatt
    41761 ttattatgta attggtatat aatgtatata taggggggac attttatgaa tttcagcaat
    41821 atttttatcc aagttgcagt tttatttata attattttag ttggatattt tgtcagaaaa
    41881 ttcaacttat tagatgacca ctgcacatct aagctttcaa ctttgacaat gacagttttt
    41941 ttaccatcaa tgataattag ctccatgcaa attaactttg atagtaaaat gatacaaaaa
    42001 atactattgt tgttatttac atctttgatt atgtatatag tttcaattat aattgcattt
    42061 ttattgaaat acattttaaa atgtaatgat aaaaaagatt tgggaatata tcagtatata
    42121 gttgtttttt caaatgttgc ttttatgggt tatcctgtaa ttgaagcagt tttaggtcat
    42181 gaagcaatat tctatactgc aatattcaat ttgcctttta acttattttc tttcacttta
    42241 ggaatttatc ttttatctaa aggcagtaca agtagaggtt tttcaataaa atcacttata
    42301 agccctgcta caatagctat tgttattgga ctttttttat ttgtaacagg acttaggtta
    42361 ccccaattta taaacgagcc acttgagatg ttgggaagta taactacacc aatatccatg
    42421 attatcattg gaagcttact tgctaattct tcagctctcg attgttttgt caacaaaaaa
    42481 ttatatatag tcacttttat aagattattg gtacttcctg tgattgtgta ttttattcta
    42541 aaaggatgga taaatgataa gatgatttta gctataccag tagtaatttc ttcaatgcct
    42601 gctgctgcaa atactgctat aatggctaat caatatgact ccaatataac actagcttca
    42661 caatgtgtgt tttttacaac actattttca gttatatcta taccttttat aagtatttta
    42721 ctcttatctt gatttatttt tttatgtatt atataataac atattcaata aattacaaat
    42781 ataaacattt tattgtagta tattgatgga attttttcct agatatttgt caataatatc
    42841 tatatgtatt atagaatagg aggcttaaat atggatatgg atttactctt taaaatagta
    42901 tttgctatag ttgctatagg tgtttctgta aaaatcatta aaactgttgc tagtttagct
    42961 tttaaaatag cgttgatatt gctaataatt ttatttgtat atagaatgtt tttgtaaaca
    43021 tttaaaaata agttttttaa cacaatagag aagtaaaata gattatcttt aatgtaaatt
    43081 ttttattaaa gacactctat tttacttctc tattagcttc tttaaattaa atttttatta
    43141 tatcttccca taatataaac atcttcaaat tttccatctc tgattacagc atatttttta
    43201 gttccctcta tttcaaaacc tagcttttta tataaattta atcccttttc attatccaca
    43261 attacttcta atcctactct agttaacata atccaattat ctgctatatc taaaagttgt
    43321 tccataagct tcttacctac tcctcttccc tgataattct ctgcaacact tattcctatt
    43381 tctgcgctat gtctcaatcg tggagaagaa tttacatgta acccagcaaa acctattaca
    43441 tctttttctc cattattatt agtttcagct acaaacatat aatcattttc tcccaaagaa
    43501 gctaacatag cttcagtttt atcgactctg tcactcatta atgccaaagt atttctcata
    43561 acactgtatg ttcttctaat ttcattaaaa gcttgtgcat cttctcttct tataggtctt
    43621 attgttatat ctataggctt actcatattg gattccccct caaacataat ctttattttt
    43681 aattaaaatt ttacatcttt attttatact gttcaaatct atgtatgctt ctacctgagg
    43741 tacatatatc atattatctt ttatatgtgt acttccaaat tcttttaatt ctgtaccttc
    43801 tttatcctta gttattttat atctaatgga ttccatacct tcaactactt cagcatgaaa
    43861 aaacatacct tcatattgtt taaatctaaa attaaaattg tctttagtaa gttttattat
    43921 catattttta tctactcctt atataattga tatttttctt attattagtt gtatatatac
    43981 tgcttattca tattaatata ttataactta tcatttattt agtataaagt tataaataga
    44041 tatatttata cttattttac aatctttctt caattgatat ataatatgtt tatataaact
    44101 aatgtatgtg aggtgaaata tgagcaaaaa aacaaaatat ttttctttaa ttctctttcc
    44161 tattgctttg cttttaaatt ttatagccag caaagttcca aatattgttg aaaaatatta
    44221 ctcccaattc atagataaaa taattgtaca aatattgagt aaagtttctg gaattttccc
    44281 attttctctc tatgagatta caatgtacat aatagttata tctatcttct tatttttatg
    44341 ttgtacttta tctacaattt ttaataagaa aaaaaaatta aacatatatt taaaaaattc
    44401 tattttaaat atattatcca ttgtatcaat agtctacttt ctttttgtag tgctttgggg
    44461 aataaactat aataggattc cactagaaac cacacttata aataactata atttaaaaaa
    44521 caatacctct atccaatcaa aacaatatag tgttaaagag cttactaaat tatataaatt
    44581 ccttgtaatt aaagcaaatg aaactagaaa actcacatta caagataaaa atggtattgt
    44641 aaaatctaat acagattata atggtgtcat aaatagagct caactaggat acgataatat
    44701 cttggatata ttacctagtg ttagtggtag ttattctaag cctaagtata ttatttcatc
    44761 aaatctaatg tgctatacag gaataactgg tatatacttt ccttttacag gtgaggcaaa
    44821 tgtaaatata gcaatacctg acttatatat tccttgtaca gttgaacatg aaatggcaca
    44881 tcaaagggga tttgctagtg aagatgaggc taattttata gcgtatctta cttctataaa
    44941 acaccccaat attgatttta actattctgg atatatttta gctttaaatt atactgcttc
    45001 tgctttaagt aaggttgatt ataatgcata tgttgatatt tctgctggca tttcagattc
    45061 tgtccgtaga gatttaaaaa atgaaagtga attttggcaa aaatatgaag gtaaaattaa
    45121 tgaaatttct aatgagttta acaattctta cttaaaagct aatggcgtta ctgaaggtac
    45181 tcagagttat ggtaaaatgg ttgatttatt gctaacttat tatgaattat atccatataa
    45241 ctaaacacta caattcaaaa ttttattcat atacagctga tattaaatca gctgttttct
    45301 atttaaataa attatttaac ttcaagcaat cttatataat ttgatagtac ttatactatc
    45361 tgtataacat atcaattcta actattttag ttaaaacatt tctattatct tttttaataa
    45421 atgttttaac taaaattttt aaaacataaa acttccacat tatttcacta tctatataaa
    45481 aatctaaaat ttcacatata aaattacata actaaaaaat cataaattta tagaaaacat
    45541 atattcaaaa taaaaaagca tgtatcaaaa cttgacacat gcttataatc ttatgtatat
    45601 atatcatttt gtcacaataa aaatttactt gtaacactga tatttttaaa caaaatagtc
    45661 cttatttaat taaattaaca ttaattaaat tcgtactcat tttgctatca ttaaacatta
    45721 cttatagtaa ttttctaata cactatttga aacttccttc ccttgaaaac ttttcaacca
    45781 attctcatat gctgagtttt tccatacact accatcatta aatgttactt gttttacaca
    45841 agatataatg tactttacac catgctctcc agttgattgt ttccatttat caaacaatag
    45901 aaaggcatca ttttgattct tacctggtgc tattgcattt tgctttgcat attctttctc
    45961 catttgtttc cattctttca accaattttc tacccatgcc ttgccttgtt gtttttcaaa
    46021 catacttatt atatcctgtg gtggtgattg ttgcattttt ctataagtat gtgaatatga
    46081 ttttggagac acaggagata tgcctgtaac aataccatag tctacaccag ctgggctaaa
    46141 tccaacactt cctacttcgc catctgctgc cacattttga gcatcccaat atagctcaag
    46201 tggttttcca tttttatcat atgctaagca tgtaatttca taatccataa ttgccttttc
    46261 actgctattt gttaagctta taacattgct aggccaatga tatggagtat catcatactg
    46321 tattttgcta ttatttataa ataatggaat attctcatta taaacaagac ctttactact
    46381 ttgaatatct gataccttct ttgtgacagt acttaccgta tttgctaagt atacatttgt
    46441 tttttctgaa ttggtcgtac taagagaaaa tgttgttgtc gttccagtaa tcagcaaagc
    46501 aacaactaaa ataggtaagc tagatatttt tttatatctc acaattcttc acctcttttt
    46561 ctattaactt ataataaaac aatttaccaa aacattaaaa tctatgttaa cataatttac
    46621 caactgttct agtaactata tcctatcata gttactatca agtttcaata ctattgatgg
    46681 aaattttcac tatattaaat ctttttttaa ttttataaat ttacaatatg atttaactca
    46741 tacatatata gtcaaattag aatataagtt tcttaaattt aatgaagttt ataaaataaa
    46801 aaatgactag ataattaaat actgtaaata aaaacttatt acaaaagtat ttaaaaatct
    46861 agtcaattaa tatatatatg aattgtatac tataattttt caatctcttc tagcaactca
    46921 tcaactaatt tgttaccatc aatcattcta actatttcac cctttttaaa taaaagacct
    46981 tcacctttac ccccagcaat acctatatct gcttctctgg cttcaccagg tccatttaca
    47041 gcacagccca taattgcaac agtgatattt ttttccatac tgccaatctt ttcttcaacc
    47101 tcatttacaa cactaattaa gtctatatta catctaccac atgtagggca tgatataact
    47161 ttaatcttat catttaaaag tcccaaactt cttaaaatct gtttaccaac aataacctct
    47221 tcaacagggt cgcctgttaa agatattcta acagtatctc caattccttt aagaagaagt
    47281 gctcctaccc ctatagaaga ctttattgtt cctttgtgaa cacttccaga ttctgtaatt
    47341 ccaatatgaa gaggataatc aactcttttt gatattaatt catatgcatc aacagtttta
    47401 taaatatcgg atgattttag agatataact atattatgaa aatctaagtc ttcaagaatc
    47461 ttaatatgtc ccattgcact ttcaactaat gcttcagcag ttgcagagcc atactttttt
    47521 aaaagttctt tctctaaaga acctccatta actccaattc taatttttaa atttctttcc
    47581 ttgcatttct caactaccat cttaactctc tctatacttc caatattacc agggtttatt
    47641 cttattccat ccacaccttg ttctatagct tcaagggcta gcttataatc gaaatgtata
    47701 tctgcaataa ttggtatatt tacactagac tttatctttg ctatattttt agcagcttta
    47761 atatcaggaa cagcaactct aactatatca caaccagctt cctctaatct ctttatttga
    47821 gctattgtag catctgcatc tcttgtatca gtatttgtca tagattgtat acttatagga
    47881 ttttctcctc ctatttttac agttcctaca cttacttctc tcgtctttct tctctcgtaa
    47941 ctcatattcc acctctatat attattttat attgaatctc tttaaatatt aaaatattat
    48001 aacctacatg tatattataa attaaaaagc tatctagtta aataagaata aatttcatac
    48061 ataaaaatta atttattctt atttaaaact acatagccta ttttcttaaa atctctaaaa
    48121 aactaaatca ttgaaataat cttagtatat ctttatatgt gataaaaagc ataaataaca
    48181 ttaaagctcc aaaaccaaca acatttatca tgccttcttt atttgggtcg agttttttac
    48241 cacctctaac agcttctagt aacagcataa gtattctcca tccatcaagt gctggtattg
    48301 gtaataaatt tactatacct aaatttaagc ttatgacagc tgctaaatac actacattta
    48361 tgatgcctgt acgagcagca tctgatacca taccaataac acctactggt cctgctacag
    48421 catttccaat ccctcctggt acacgtccgg taatcatttg acctagaaat gttagcatct
    48481 gttttgtcat atctacagta gttttacatg catttactat tgaccctaaa aagtcttttt
    48541 ctctttgtgg ttgaatccct atttcatact ttccattgtt atttttaggt gttacattta
    48601 caactttatc acttccatct ctagttatac taagttttaa ttctccacca gaagaagtat
    48661 ttattatatt tgcaacttca tcccaagtct taacagaatt accattaatt ttatttatct
    48721 tatctcctac ttgaagccct acagcctgtg caggagtatc tggcattatc tttcctaatt
    48781 tagtcgttgg agaacctata tacaaaaata ctgggactaa aagtattgct gctaatatta
    48841 tattgaatat tggtcctgct acaatagtac taaatctttg taatatagac ttgtttccaa
    48901 aagaatttgg acttatttgt tcttcatctt caccttccat gctgacatat ccaccaattg
    48961 gaagtgctct tatagaatac tctgtatctt tttttacact atatatctta ggccccatac
    49021 ctatagaaaa ctcatttact ttgataccac ttctttttgc aaatataaaa tgtcctaact
    49081 catgtattaa tacaattata ctaaatagta ttaatgcggc tattatagtc ataaattcac
    49141 cttcctattt ttttatcaga tttgcaacat aagctctact ccatctatct gtttctaaga
    49201 tttcttctaa tgttggttca cttatgctac tatgaacttc taaagtcttc tctatgtaat
    49261 atggtatgtc atagaaacca attttatcct ctaaaaattc acttactaaa acttcatttg
    49321 ctgaatttaa aacagaagaa taagttcctc ccatttttaa acactcatat gccaatttta
    49381 aacatggaaa agtttctaaa tctggttctt caaaagttaa agtactaaat tttgaaaaat
    49441 tcattctttc aaagctactt tccattctat ctggatatgt aagagcatac tgtattggta
    49501 gtctcatatc tggacatcct aattgagcaa ttattgagct atctgtatac tgcaccattg
    49561 aatgaattat gctttgtggg tgaactacta catctatatt ttcttgttct actccaaata
    49621 accatctagc ttctatcact tcaagtcctt tattcataag cgttgaagaa tcaatactta
    49681 tttttcttcc catactccaa tttggatgct tcaaagcttc gtttttagtt atatttgcaa
    49741 gttctccctt tttctttcct ctaaatggac caccagatgc tgtaagtatt atcttttcta
    49801 tatttttttt attttctcca tttagacatt gaaatatagc actatgttca ctatcaacag
    49861 gaagaatatt tacattgtat ttttctgctt ctttcattac aagttcacca gcagttacca
    49921 acgtttcttt attcgctaat gctatgtcta ttcccttctt tatagcacaa agagttggga
    49981 ctaatcctat catacctact acagcagtta aaaggacatc cacttcatca agtgatgata
    50041 ttatttttaa tccttccatt cctgctaaaa cttctatttc tatattttta ggcaacattt
    50101 cttttaattt caatgcttta ttttcctcaa aaactgttac atatttaggt ttaaactcta
    50161 ctatctgttc tagcaataat tcaatattac tgttagctga tattgcaact atctcaaact
    50221 tatctctatt atctctaact acatccaaag tttgtttacc tatagagcct gtagaaccta
    50281 aaattgatat ctttttcata taataatcct ttctaataat aaatataccc tgtcaaaaca
    50341 ttataacact actaaaacaa ttatttttac tattcataga aatttcatat attattccac
    50401 agattaaaat taatctatta ttttttgtat tttgtggaat attataaaat attctagtat
    50461 tattaaatgc ccttttttat ttccacaaca tcttctattt tacagtctag tgctaaacat
    50521 atcttctcca ttgtatccat agaaacagat ttatcatttc ctagtctgcc taaaacagaa
    50581 atacttatac ctgatatatt tacaaattcc attttcttta tttttttgtc aattaacaat
    50641 ttccataatg gagcgtatga aatcatgtta tcacctcgca aaatatattc tatcacattt
    50701 tatctatttt ggaaaatttt catctattta gataaataat tatttatcta aatagatttc
    50761 aattatagtt tattaaatat aaatatgtta aaataaaaca aaagcataag ttcaaaaatt
    50821 aaactttata tatatttatc tcattatttt actaaaacat aactatataa aaaatattta
    50881 ctattatata tctatttaaa acacattatt atagtatcat ataaacatat gtaaatatat
    50941 aattaaaaaa gctaaagatt agtaaattta taaaaattat attttgaata aaaggagaaa
    51001 gaatgttgta tttattaaaa attaatcaat ttgaaaaaag ttatgatata ggaattttta
    51061 aaaatgaaca atcaatatat aaatttattg aaaaaatacc ctttgtaaaa aaagataata
    51121 gtaattttaa ttatacaaat tactatatgg aatttgaaga tattcctgaa tattatgaag
    51181 taaatttcaa taattattta tatattatta ccaggttttc attcattcca gatggaactg
    51241 agatattttt tacttgggaa gaaatccatt gttgggatga aaaagttgct accgagaaaa
    51301 cttttataaa tggcgaaaca ttagtggatt catataactt tccaaataat gaagtgaaag
    51361 actacataca aaagcgagaa tcactatata tagaaacaaa aaaatattat gaagaaaaag
    51421 gattaaaaat tgagagacat gcactcggtt cagaagatgg tgaatatgtt gaacttacaa
    51481 atgattctat actttattta ctagatatag aagcagttga aataagagaa caatcaaaaa
    51541 atatagaaga atttctatat aagtacaaaa aacgttttaa ataatttata ttttaaaata
    51601 cataacaata cattgagtca tttaacgaga tataaaatga ctcaatgtat agactgataa
    51661 aaataattat attatttttt agttacatat ttgttaaaaa attctttttc ttctatcggt
    51721 ttagaaaaat aaaacccttg tcctacatca catttaactg tatttaaaaa ttccaagtct
    51781 tttttagttt caataccttc acatacaaca gacatgccta tacgatgtga catttcaata
    51841 atacactgaa taatactata tactttctcc tggttaaatg tttctttaag taagctttta
    51901 tctaacttca atccattaat agatagagaa cataaaagac ttaatgaaga gtatcctgat
    51961 ccaaaatcat ccatagaaat taaaaatcct aactttttaa gctcctctaa aatcgaaata
    52021 actggttgag atatttcatt aaaagcactt tcagttacct ctatctctat atacttaaaa
    52081 ggaatttcat attctttaac agtatctaaa aacctttgat aaaaactatt ttggtaaata
    52141 gtaacccttg aaaaattaac tgcaatcgga tatgtatatt gatttttttt cataaacgtt
    52201 ttttttacaa atgaacacgc tttttttaac atataaaagt ccaattcaat aataaatcca
    52261 cttttttcaa acaatggaat aaattcatct ggtgataaaa aaccaagttc tggagaaaac
    52321 catcttacaa gagcttctgc gctcacaaca tttaaagaag atatttgaaa tttaggttgc
    52381 aaatacatat gaaattcttc attttctatc gctttataca tataattata aatactattt
    52441 tccatttgta actgttttaa cagattttca ttataccata ctgtggagga aattcctctt
    52501 gttttactta ccttgtgtgc aatatttgcc ttatccatta tagaattgat agatttataa
    52561 cctaaattat caatttcaac taagtacgct cctatacaat aagatatagt ttgagttaca
    52621 ttcatatcta attcagagat tatagcatta gttagcattt cccgaatatc ctctaaaaga
    52681 gaatctctat attttgcaag tattacaaaa ttatctgaac caattcttgc acaagtttct
    52741 ttgatattaa aagttttaga aagtgcagct gcaactatta ttagaacttt atctccatat
    52801 tcatatccat gtgtatcatt aatatattta aaattgtcaa tatcaatatt tagcagtaca
    52861 tactctttgt tagatgcatt gtgcaaaatt tcaatcgctc tgttttcaaa tgcaacctga
    52921 ttttttattt ttgttaaatt atcagtataa aatattcttt taaacctttt tttattataa
    52981 tattcccaaa ttaaaagact tattgttgag aatataagat aaataaatag tgcagtagca
    53041 aaagaataca attttgcatt agagtgtttt tcagatataa aaacaatttg attagacaac
    53101 acagaatact cttcactcaa tttatataat ttatcacctg aagcaccatt tctaacttct
    53161 ataatttctt tcttcataga ttcccacata gaatccattt gatttagttt ttgttgaaat
    53221 tctttattat cacatctttg aaatccattt tctccattac ctgttcttag ctttatcaga
    53281 atattatcca gtcgttttat caagtcatca tttctttcat tattcaattc ttgcttaaca
    53341 accttttgag tttcactgcg aatagtacca gtgtgactta taattttaat atgctctata
    53401 ctgtgatata gagaaaatat aaaaagaata ataataacta gccaaatagc agaataaatt
    53461 aaaaaatcat attttttctt cattattgtt acctcatttg taatatatat aatttgcaaa
    53521 taatcaatct cttataaaaa atgattatca atattttaca gtgatatgta tttatcttaa
    53581 atagtttaat catttatacc ctataaattc tacaaattca tcacctccaa cacaaacagc
    53641 aatatacgtt tttctaaaat ttctttttaa acattcatca acattatcat taaatcattt
    53701 ttaaattact caattaattt actgcatcac ttcttttctt acaaaatatc accccaataa
    53761 tatatttgta taatgtcttt atgtctcttt ttaaatttgg catatacata atctatattt
    53821 taataaataa ttaaaatact atttacctac aatttaactc tttgaattta ttttatcata
    53881 ttatgtaaat atattccttt tttttggtat a
//
LOCUS       DAEORM030000025        51489 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.025, whole genome shotgun sequence.
ACCESSION   DAEORM030000025 DAEORM030000000
VERSION     DAEORM030000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 51489)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51489)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 51489)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51489
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.025"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            121..309
                     /gene="rpmB"
                     /locus_tag="KRH23_001936"
     CDS             121..309
                     /gene="rpmB"
                     /locus_tag="KRH23_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HHS5225216.1"
                     /translation="MAKVCSVCGKGKVSGNQVSHSNKHNKRTWSANLRSVRAIIDGAP
                     KRVKVCTRCLRSGKIERA"
     gene            complement(469..621)
                     /locus_tag="KRH23_001937"
     CDS             complement(469..621)
                     /locus_tag="KRH23_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate translocator"
                     /protein_id="HHS5225217.1"
                     /translation="MRNNKSKVLLGILCLATGMAVILSMLLPGWIWSALTALILIGCG
                     ALLFFC"
     gene            complement(719..1195)
                     /locus_tag="KRH23_001938"
     CDS             complement(719..1195)
                     /locus_tag="KRH23_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="HHS5225218.1"
                     /translation="MNLKRSNEKREEYRRMYSDKESFLSLIQNFTSVSIAKELTLKNI
                     ELETSFICEYKGKEVDIIYKVFSKSGKVSHYIVLEFQTEMDTEIVPRLKSYREQIWKS
                     FIMKKSLEEIEDKNFKLPKVIPVVLYSGPERLSRKKGILDIVESISEFSNNSSMKN"
     gene            1414..2175
                     /locus_tag="KRH23_001939"
     CDS             1414..2175
                     /locus_tag="KRH23_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HHS5225219.1"
                     /translation="MEYTVQKLSKLAGISTRTLRYYDEIGLLKPLKINSSGYRIYGQN
                     EVNKLQQILFYRELGINLENIKNIINSPNFDSLSALKEHHNKLLAKRKQIDLLIENVT
                     KTIALKEGKYTMTDIEKFEGFKEKMIDENEKNYGTEIREKYGKDIIDTSNKKLKNMSK
                     QDYENWQNLNIEIISKLKKAFKTGDASSELAQEVAKLHHKWLSYTWNTYSKEAHSSLA
                     QMYVYDERFTSYYDREQPGLAKFLRDAIVIYTRDK"
     gene            complement(2435..4363)
                     /locus_tag="KRH23_001940"
     CDS             complement(2435..4363)
                     /locus_tag="KRH23_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HHS5225220.1"
                     /translation="MHKRLLTLFKLLNESDDKITCKTLSNHLKVSERTIRNDITSING
                     TLEKNGAIIKIKKGEGYYIDILNLALYQQYLALISDDIMDSSEIPDSPIERNQYILKY
                     ILYNNTYIKLEDLANSLYVSKFTILNDIKRIKPILSKYNLILVSKPYYGVKVEGKEID
                     IRRCISNNMINRNFENYIIGITDREIELFNNVDLIELQRVVLSEINKFNINFLDFNLK
                     NFIIHLAITVSRILDGYCLDNVLDVVLTDFQSNTTVENIFNYIESKYTIIISKADRVY
                     LYNHFITKSSLLDNVSNRVDTKIIEYVEEILEVINNQYTFDLRNDSVLFDDLVLHFKS
                     ILNSKSYNLNKVNPLINTIKSNYPLAFEITLNAIEKVFKNSIYSLTEDEIGYVSLHIG
                     AGIERFFQSNIKCKNVVLVCGSGYGSSRLLEVQLNKVFHDKINILQCLSFNQFLASEL
                     SDVDIIISTIPLNHDSIPIVLVDLKLLKKDIENISKSITNNSHIYSNLLDNFFDKNLF
                     IVNPKIKDKDELIKLMCNKLTQSEIVFPSFAESVFYRESLSSTNIDDFLAIPHPMELS
                     SIRTKICISILDEPIYWSEDSTVKLIMMLAINKDDYIKINSIYDILLKIIHDNDIRDS
                     ISNCNDFDNFLSIIKSIV"
     gene            4597..5049
                     /locus_tag="KRH23_001941"
     CDS             4597..5049
                     /locus_tag="KRH23_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HHS5225221.1"
                     /translation="MVLQEKYIFIDKDLKSKEEVLNFIADSAYILGITTNKEALLKDL
                     LKRENEFPTGIKDGFAIPHTKSVNVKEASILYIKTTNELEWKTLDDSKVRYVFSLLAP
                     HKNEGNIHLKTLSKLATCLMEDDFTSEVKNASDASHLVKYITNKMKEE"
     gene            5052..5360
                     /locus_tag="KRH23_001942"
     CDS             5052..5360
                     /locus_tag="KRH23_001942"
                     /EC_number="2.7.1.202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_function: GO:0022877 -
                     protein-N(PI)-phosphohistidine-fructose phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_function: GO:0090563 - protein-phosphocysteine-sugar
                     phosphotransferase activity [Evidence IEA];
                     GO_function: GO:0090582 -
                     protein-phosphocysteine-D-fructose-phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HHS5225222.1"
                     /translation="MKIVAITSCIAGLAHTPMAAKALEQAASKMGHEIKVEQQGAMGR
                     VNTITKEEAQDADFILIASDQTISGMERFDGKKVIKVKIGIALKKPEAVLTKCIEAIS
                     "
     gene            5474..6565
                     /locus_tag="KRH23_001943"
     CDS             5474..6565
                     /locus_tag="KRH23_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HHS5225223.1"
                     /translation="MSKKNKSLLSELKGHLMTGISYMLPLVIGSSLVVAIPKLTALAV
                     GITSLDAYKNVSGFYHILYLIEQVGWTGIGLLNTVLAGFIAFSIGEKPAMGSGFIGGL
                     IASNTNAGFLGAVIAGFFAGYVCKFLKKKIKISGSASGMMPLITVGLTGFLMSVVLAG
                     PLGNINTSLNAWVAEMCQNGTNSVVLALILGAMIGFDLGGPVNKAAWMAGNALLLEGI
                     YLPAILVNCAIVIPPLGYGLATFIRKSKFSNALAETGKGNIIMGIIGITEGAIPFTLT
                     NPLKLVPVNMIGCALGVGLSALLGVHAIMPPVGGLYGFISIGSGWAYLVGAIFGALVI
                     AILSTTLVDFNEDETTENTEFDEIELDIM"
     gene            6640..7185
                     /locus_tag="KRH23_001944"
     CDS             6640..7185
                     /locus_tag="KRH23_001944"
                     /inference="COORDINATES: protein motif:HMM:NF013256.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5225224.1"
                     /translation="MKKTKVHVVPHSHWDREWYFTTSRSKIYLMKDFQDILDILEEKE
                     DFKYFTMDAQASLLDDYLKWRPQDEYRIRDLVQRRRLVIGPWYTQTDQLVISGESIIR
                     NLYYGIDRCNEFGEPMRVGYVPDSFGQSAQMPQIYRGFGIDSSLFWRGVSDDMVDTTE
                     FIWKGSDGSKVLAVQIPFGYY"
     gene            7465..9318
                     /locus_tag="KRH23_001945"
     CDS             7465..9318
                     /locus_tag="KRH23_001945"
                     /inference="COORDINATES: protein motif:HMM:NF019368.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004559 - alpha-mannosidase activity
                     [Evidence IEA];
                     GO_process: GO:0006013 - mannose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 38 C-terminal
                     domain-containing protein"
                     /protein_id="HHS5225225.1"
                     /translation="MRIHKSIFSSRSDLKIMNNKLENYITNVLEPLLTLSYSLGNEYP
                     HLVIKDIWKLMFENAAHDSIGSCNSDTTNEDVYTRYKQARDLSINLLDLHMRLISTQI
                     KNNNEEITLTIFNGFPEVRNEVVEFDTYIPGQDFVIKNKNGEILNYIIKEKEDITNYI
                     LTQTIRLNPSKKIYIPKTVYRAKIALSVKDIPPMGYTQLVFELDTKNKCEIKTSNCKE
                     IENKYYKITANKNGSLEILDKESNKTYKNQAVIEDNGDDGDSYNYSPPRKDIYVSSLD
                     SVSSVEVLKSNIQEEMIVKYSLTIPTSLEERAIGKVSVKMPVTMKITLEPKEQIIKFN
                     VNIKNNQALSHRVRVLFNTEIASKFSIADQQFGIIQRPTVLEKDLALWKRDNYSWQEK
                     PITIEPMQSFVTLEDGQRGIALITGCVREYQIVGDNLDTIALTLFRSFGYMGRENLLY
                     RPGRASGEKIIATPDAQLLKELNFDFGLYIYNNKFDEANVANTAKRFLTPIQIYEYAD
                     FLNGRLIFAFNDEKQIYENEFSLMNVNNSNFTVSAIKKEEKGDGIVVRIFNGMKNEDA
                     KGSLNINKNVNDAYSAMLDEIYDNTSKLKVNTKTVEVNSLSHCKVQTIVIK"
     gene            complement(9635..11971)
                     /locus_tag="KRH23_001946"
     CDS             complement(9635..11971)
                     /locus_tag="KRH23_001946"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HHS5225226.1"
                     /translation="MLDTKLKKFKDKYIVTIIVFILMLSASLGMISQYSTIQAGAKGG
                     AKNPFEQESFVDSIYKGSYVLYHNMKEEQEGKMIQPSKLFINEETMNYIKNVSKEKDT
                     YDGSETYYTNDSINADFNENFENWEHFIKASGKNLKYYLVDKESNFEFFNDNKELGVL
                     DTTKNDASKENSDENQSKNTEMNDEERQKQITDIKENYRFYVVMNFDKDGKVNIVDSY
                     GVNQKVINQMLLSKAREDLMDTSLGGNSISYKLSPIKNITLVYAVPKVISKGDSVEYG
                     YGNTYFDDGIISYISNVENNSYYKISGMILKIILAIVVIVALAFPYRKSKELLGFDTL
                     SRIPLEILFIALAIIQGLVDLYPTVIISNTLSGNYVEYLINNDISAKMASILVSLMNL
                     TYWFVIFSIIFVFIILLKHILNVGIREYFTKHTVTGMFFVWLKKAGKTVINQIRTINL
                     KEKPNKTIVTILGINLLIIVIMCSMWFFGIILALIYSVVLFKILSDYSKKTIYEYNQL
                     LDVTKKISDGNLDVNMEKDLGFFNPIKDELGNIQTGFKKAVDEEVKSQKMKTELISNV
                     SHDLKTPLTSIITYIDLLKDESITDENRKLYIDTLDRKSQRLQHLIEDLFEVSKANSG
                     DVYLNIVNVDIVSLMKQTLLELDDKLADSSLIVKNNFSNEKIILPLDSQRTFRVFENL
                     IINISKYAMPNSRVYIDILETDNKVNIMLKNMSASEIDFSVDDIMERFVRGDKSRNTE
                     GSGLGLAIAKSFIELQGGKMNISVDGDLFKVTITFNKN"
     gene            complement(11943..12659)
                     /locus_tag="KRH23_001947"
     CDS             complement(11943..12659)
                     /locus_tag="KRH23_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HHS5225227.1"
                     /translation="MNSYNILVVEDEKEIADAIEIYLLNQGYNVFKGYNGLEGLKVIE
                     NQEIHLAIVDIMMPKMDGITLTMKLRENYNFPVIMLSAKSEEVDKIMGLNIGADDYVT
                     KPFKPLELLARVNSQLRRYTKYLNMVGNKEQKVESDDSVFAIGGLELNENTKEVSIDG
                     KYIKTTPIEFKILSLLMRNAGRVFSADEIYERVWNENAVNTDTVMVHVRNIREKIEID
                     PKNPKYLKVVWGVGYKIEKI"
     gene            complement(13074..13730)
                     /locus_tag="KRH23_001948"
     CDS             complement(13074..13730)
                     /locus_tag="KRH23_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HHS5225228.1"
                     /translation="MELQDTIFKRQSVRKFKNQDVSDEDILKMIKAAGAAPSGKNIQN
                     WHFVVIKRRDLMEKIADVITKKQQEILVEMDKVSVDKANRFRKFVKNFTLFYLKAPVL
                     VLVFTKVYNPSGYYELELIDAPKETIDKLFIRNPGMQSLGAAIENFTLSAIELGYGSC
                     WLTSQNYAADEIEAVLEAETGFEKGEYFLGAMLALGVPEDNLKSPSKKPVEEICTFIK
                     "
     gene            complement(13785..14414)
                     /locus_tag="KRH23_001949"
     CDS             complement(13785..14414)
                     /locus_tag="KRH23_001949"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HHS5225229.1"
                     /translation="MVDSIIFDLDGTLWDSTEEVCKVWQDVLSEHKEIELSVTKDLFR
                     SLMGLSFEEIANRLFPNLSEEERMNLLNECSLKECDYLSENGAKLFDDIEDTLKLLSK
                     KYKLFIVSNCQAGYIESFLKAHKLEQYFIDFECPGNTGLHKGENNKLIIERNKLINPI
                     YVGDTQGDANSAKFVGIPFIYAKYGFGNVDVYDYFIDSFKDLLEHDILK"
     gene            complement(14545..15186)
                     /locus_tag="KRH23_001950"
     CDS             complement(14545..15186)
                     /locus_tag="KRH23_001950"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004788 - thiamine diphosphokinase
                     activity [Evidence IEA];
                     GO_process: GO:0006772 - thiamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HHS5225230.1"
                     /translation="MKICIVLNGEIEDYEVTRDIIIKECYDCIICADGGANHTYKMEI
                     MPDYILGDLDSVEEEKINFYKNKGVKFEKFPSKKDETDTELCLFLAKTLKANHIDFFG
                     ALGGRIDHTLANIKLLYYLKEDGIYSRILSDKEEMYIVENEEISLYGNPGDTISVIAI
                     NGDAKGVTLTGLEYPLDNYYMKYSVPIGISNVMLSNSCKIKVEQGCVLVVRNL"
     gene            complement(15195..15866)
                     /gene="rpe"
                     /locus_tag="KRH23_001951"
     CDS             complement(15195..15866)
                     /gene="rpe"
                     /locus_tag="KRH23_001951"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004750 - D-ribulose-phosphate 3-epimerase
                     activity [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HHS5225231.1"
                     /translation="MIKLAPSILSADFAKLLEDVRKVESAGCEYLHIDVMDGHFVPNI
                     TLGPLVVKSLKKENINMVFDAHLMIENPDQYIEEFVKAGCDIITVHQEACVHLHRTIQ
                     NIKSHGIKAGVVLNPATPVDTIKHVLPDLDMVLLMSVNPGFGGQSFIPCVLDKIKELK
                     AIIDSQGLNIDIEVDGGISPKNVAEVVQAGANVIVAGSAIFGSDDIQETVNLFRKNAS
                     LEELV"
     gene            complement(15871..16755)
                     /gene="rsgA"
                     /locus_tag="KRH23_001952"
     CDS             complement(15871..16755)
                     /gene="rsgA"
                     /locus_tag="KRH23_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HHS5225232.1"
                     /translation="MLEGKIIKGISGFYYVDTYNGIYECKARGIFRKQKITPLVGDRV
                     KISIVDEDEKKGILEEIDRRDTELIRPPIANVDKALIVFAIKNPKPNLSLLDRFIVLA
                     EKENLETVIILTKADLDDNDTLETVKNIYELSGYKVIPVSNITKLNIDKVKEELKENV
                     VVFAGPSGVGKSSLLNEIDENFKLQTGVVSDKIKRGKHTTRHAELLKLEFGGMVADTP
                     GFSSLALEDIEEVELKDYFIEFDKFNDCKFGSKCIHENEPNCAIKEAVTNGEISKERY
                     DSYIQLLHEIRQNNSRRY"
     gene            complement(16853..17590)
                     /gene="ymfI"
                     /locus_tag="KRH23_001953"
     CDS             complement(16853..17590)
                     /gene="ymfI"
                     /locus_tag="KRH23_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P 5-aminopentanone reductase"
                     /protein_id="HHS5225233.1"
                     /translation="MKKKTVLITGGARGIGKAMSKAFAKEGYNVLVNFNKSENEAKEL
                     YTILNEKNFSVKLFKANISNREDVEDMVDYCIKEFGGLDVLVNNAGVSQDKLFTDITD
                     EDWDNMMNINLKGSFYCSQVALKYMISEKKGNIINISSIWGISGASCEVHYSITKAGI
                     IGMTKALAKEVGPSNIRVNSIAPGVINTDMLSGYNEEDIDALVEETPLMRLGTPEDIA
                     NCAIFLASDKSNFITGQVISPNGGFVI"
     gene            complement(17698..19707)
                     /gene="prkC"
                     /locus_tag="KRH23_001954"
     CDS             complement(17698..19707)
                     /gene="prkC"
                     /locus_tag="KRH23_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861606.1"
                     /note="PrkC, as found in Clostridium difficile, has a
                     kinase domain, two PASTA domains, and a C-terminal
                     Gly-rich repeat region; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PASTA domain-containing Ser/Thr kinase PrkC"
                     /protein_id="HHS5225234.1"
                     /translation="MGDTILGNRYEIIRKIGDGGMAFVYEAKDRLLNRTVALKVLRPE
                     FVDDDEFLTKFKREAEAVASLSHPNIVNVYDVGEDGKVHYIVMEFVDGKNLKEIIQDE
                     GILDEYTALDITKQIAMALSAAHKKGIIHRDIKPHNILISNEGRVVKVADFGIAKAVS
                     NSTMTNIGSIIGSVHYFSPEQAKGKFVTNNADLYSLGIVLYEMLIGKVPFRGDSPISI
                     ALQHINDDIDFTSEEKVRIPQSVRTTIKKLTEKSSADRYQTAEELIEDIEYIEKNIDL
                     DFIKEYDDFATKKIDEKEINKVVNPTLAKPAPEKVVKPVEVADLDDDEDYYDDFYEED
                     EDEEEEEIMRAKKNQRPKSTPSKRTKKKKKKQESPKSRRRLKVIAAVLILILCAQVFL
                     AYKFLFAGGFGNKSLTVPNLVNMTLEEAQSAVEKEGLYLSVKSEEYNSEVDENCIISQ
                     TPEGGSTNVKKGDTINVVVSKGSSQASVPNVVGLTLSNAKQLIEENNLKVGTVKYEYS
                     SIYKEGTVLSQSPGAGSSRAQEGDEVNLYVSKGSEKSNTQTPTVPDKKPTTPENNTPT
                     EPGSNSGNSGGNSGGSNSGNSGGNSGNNGSNSGGSNSGNSGGNSGGSNSGDNGGSSGG
                     SNSGDNGGSSGGSNSGDNGDSSGGSNSGDNGGTSSGTGANIGKTE"
     gene            complement(19724..20476)
                     /locus_tag="KRH23_001955"
     CDS             complement(19724..20476)
                     /locus_tag="KRH23_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004722 - protein serine/threonine
                     phosphatase activity [Evidence IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HHS5225235.1"
                     /translation="MVYSCASHIGKIRKNNEDYCEGEVIDTEHGPIGIFAIADGMGGH
                     KKGEVASKLAVENIIDFLKENLLQHDNVKIDYIDDILKQAYNNVNSIVHKKSMEDIEF
                     EGMGTTLVTAIVYNNVLYVANVGDSRCYLLTDEKFDKITIDHSVVEELMMAHVITEEE
                     ARRHPQRNRITRAIGTDDMVVVDIFKKEIKKSDIILLATDGLTGFIDDEDIRDLILDY
                     EYERTSNISEELISMANDVSGKDNVSVIVIKV"
     gene            complement(20496..21527)
                     /gene="rlmN"
                     /locus_tag="KRH23_001956"
     CDS             complement(20496..21527)
                     /gene="rlmN"
                     /locus_tag="KRH23_001956"
                     /EC_number="2.1.1.192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:0016433 - rRNA (adenine) methyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0030488 - tRNA methylation [Evidence IEA];
                     GO_process: GO:0070475 - rRNA base methylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HHS5225236.1"
                     /translation="MEKKKIVLKNFTEDELKEFMKTIDEKPFRGSQIFSWIYKGAKTF
                     DDMNNIPKSLRNKLEEVSCIGHIDIELKLESKVDNTKKYLFLLDDGNIIETVMMDYDS
                     RVTVCVSNQVGCRMGCNFCASTMDGLIRNLEPWEILDQVIKIQEDTGKRVSNLVLMGS
                     GEPLDNFENTKQFLKIINEKNGLNIGYRHITLSTCGIVPKMYELADLEIAINLALSLH
                     SPYDEERRKIMPVANAYSIEEILNACRYYIKKTNRRVTFEYSLIKGVNDSEKEAKALA
                     KLLKGMLCHVNLIPINKVEEREYEKPDKAFIYKFRDSLEKNNIPATVRMSMGSDISGA
                     CGQLRRKYK"
     gene            complement(21535..22860)
                     /gene="rsmB"
                     /locus_tag="KRH23_001957"
     CDS             complement(21535..22860)
                     /gene="rsmB"
                     /locus_tag="KRH23_001957"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0001510 - RNA methylation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HHS5225237.1"
                     /translation="MDAREVGFKVLCDIEKNDNYSNIAINKHFKNLEISDMDRGLATE
                     LIYGVIENKYYLDYIINKLSKIKVKKMSTYVKIFLRMGTYQILFLDSISDYAAVNETV
                     KLSKKYDKKSSGFINAILRNEIRAKETIMDITEEDSVKYLSIKYSYNSWIIKNWIDKF
                     GQEFAEDLLEANNEKPSIYIRTNTLKISREELIEKLSEMGIVCLKVPMVEEAIKVEKM
                     KNIEKNELFKAGLFTIQDISSMIVGKVINPKEGSFVLDVCSAPGGKSTHLATLMNNTG
                     QVVARDIFEHKLKLINSTVNRLGLKNVFVERFDASEIDENSISKFDYVLADVPCSGFG
                     IIRRKPEIKYKKEEELKDITSIQKKILENASKYVKVGGTLVYSTCTIQDVENINIVTS
                     FVEENHNFEFVPIDTVNVDLDNQDKGYLKIYPNIHGIDGFFIAKLKRIR"
     gene            complement(22922..23623)
                     /locus_tag="KRH23_001958"
     CDS             complement(22922..23623)
                     /locus_tag="KRH23_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metallopeptidase"
                     /protein_id="HHS5225238.1"
                     /translation="MYPVYGGFWGFDPTMVILIPAILLTIYAQFKVSSTTNKYLRVNT
                     RRGYTGEQTARRVLDSNGLYDVKIEMVRGHLSDHYDPRRKAVRLSEDVYYGTSITSVA
                     VAAHECGHAIQHAKGYAPLQIRSSLVPVVNFASSISWFLIFLGFIMAGPFLKIGILLF
                     SASVLFQIITLPVEFNASSRAIVQLGNLGIIDESESRQSRRVLSAAALTYVAAALVSI
                     LQLLRLLLIAQRRND"
     gene            complement(23692..24444)
                     /locus_tag="KRH23_001959"
     CDS             complement(23692..24444)
                     /locus_tag="KRH23_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF116 domain-containing protein"
                     /protein_id="HHS5225239.1"
                     /translation="MTDIKKYLTSVGILILILGILIGVVNFFIISLTQIFSLMINIII
                     ISLILIILCSTAVTYRVIKGKYVNSNIMKINFNIVSGLFPIISFIASSFGMSKSDIRR
                     IYIKLNNEYIYSNKYNFNPEDIIILIPHCIQENSCKLKVTNDIDNCKECGRCNVGELI
                     KLKEKTNVKIFVATGGTLARKIIMDTKPKAVVAVACERDLTSGIQDIKKIPVLGVFNK
                     RPNGPCVNTNVDMMDIEKAIGFLTGKNILVCN"
     gene            complement(24454..25383)
                     /gene="fmt"
                     /locus_tag="KRH23_001960"
     CDS             complement(24454..25383)
                     /gene="fmt"
                     /locus_tag="KRH23_001960"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004479 - methionyl-tRNA formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0071951 - conversion of methionyl-tRNA to
                     N-formyl-methionyl-tRNA [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HHS5225240.1"
                     /translation="MKIVFMGTPDIAVPCLQKIIDEKYEILGVVTQPDKPKGRGKKLG
                     MSSVKELAIENNIPVYQPVKARDKEFIDKIKSLNPDVIVVVAFGQILPKEILEIPKLG
                     CINVHVSLLPKYRGAAPINWVIINGEEKTGVTTMYMDEGLDTGDMILKTEVNLDENIT
                     AGELHDKMMNIGAETLKETLRLIEEGNAPREVQNHEEFSYAPIMNKSLGNIDFSKSAR
                     EIHNLVRGVNPWPSAYTTYNDVIMKVWKTKVLDEKSTKDVGTIIDVSKDGIKVSTIDN
                     VLLIEEIQMPNKKRMLVGEYIKGNTIETGLVLG"
     gene            complement(25398..25838)
                     /gene="def"
                     /locus_tag="KRH23_001961"
     CDS             complement(25398..25838)
                     /gene="def"
                     /locus_tag="KRH23_001961"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042586 - peptide deformylase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HHS5225241.1"
                     /translation="MALRQIVQIGEPVLRKKSKKVEKIDEKIIQLLDDMAETMYDADG
                     VGLAAPQVGILKRVVVIDIGEELIELINPEIIETSGEQIDEEGCLSVVGEAGNVRRPN
                     YVKVRALNRNGETIELEGEELLARAFCHEIDHLDGILFVDKIEK"
     gene            complement(25856..28345)
                     /gene="priA"
                     /locus_tag="KRH23_001962"
     CDS             complement(25856..28345)
                     /gene="priA"
                     /locus_tag="KRH23_001962"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HHS5225242.1"
                     /translation="MKKYAKVIVRSNTIYTDNLFTYQIPVFLSDVIKIGHRILVPFGK
                     GNKPTEAFVFQFTDSLDEKIKIKEIIDILDENPIFRKEDLELVYWMKNRYLCTYIECI
                     NLIYPKGYKLNNYKVVLLGESLSGLNDIELKEKISTLSDKNREIVEKVIDSKGKIKVD
                     KLKYIPNLNSSLYTMNKNGIIKLCWEYKNHKNEKKVCYISLSLESDKIDDYIEQNKIN
                     VGSKQKEILSFLKNNENVEINDLLDLLNASKQSINSLSKKKLITLEFKDYYREPKSIY
                     KSVLKSIKLNNEQQEAVDEIKSNMFVDDKKPYLIHGVTGSGKTEVYMEIIEFALNQGL
                     DSIFLVPEIALTPQTIDRLKSRFGDLVGVFHSKLSEGEKHDVYKAVKAGKVRVLIGAR
                     SALFAPFNSLGLIIIDECHESSYKSEKNPKFNAIEVARFMALKNNITLILGSATPSIE
                     EYYRAKSGEYKLINIKSRANDKPLPNIEVVDMKDELDKGNRSIFSLKLQKEIRYAIEE
                     NNQVILFLNRRGYANFVSCRKCGYVFQCENCDISLTYHKKSNTGRCHYCGYEKEIPKE
                     CPECKSTYVKPFGVGTQKIEEELKYIFPDIKTLRMDKDTTSKKGALDEILNKFKDKEA
                     DVLIGTQMLSKGLDFENVTLVGILSADMILNFPDFKSFETTFQLITQVSGRAGRADKE
                     GKVVLQTYDTEHYAIKHAIEYDYEGFYEDEIKIRKAFGYSPFNNMLSVVVSGEDERLV
                     IKNIKNMHASLIYLLEKRGINDLGFILGPNPCSISKINQNYRWQILFKDENIEINLLK
                     GIIKYICITKRDLIFDKNINVSIDINPNSVL"
     gene            complement(28620..29819)
                     /gene="coaBC"
                     /locus_tag="KRH23_001963"
     CDS             complement(28620..29819)
                     /gene="coaBC"
                     /locus_tag="KRH23_001963"
                     /EC_number="4.1.1.36"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004632 - phosphopantothenate--cysteine
                     ligase activity [Evidence IEA];
                     GO_function: GO:0004633 - phosphopantothenoylcysteine
                     decarboxylase activity [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0015941 - pantothenate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional phosphopantothenoylcysteine
                     decarboxylase/phosphopantothenate--cysteine ligase CoaBC"
                     /protein_id="HHS5225243.1"
                     /translation="MLKDKTVVIGISGGIAAYKACDVVSKLKKLNANIHVIMTKSATE
                     FVKPLTFQSLSQNYVVEDMFEEPKTWEVEHISLAKKADLFLIVPASANVIGKIANGIA
                     DDMLTTTVMATKAQVLIAPAMNTNMYENPIVQKNIQTLKSFGYKFIEPESGRLACGDI
                     GTGKLANPDIIVEEVLTNLTKEQDLKGQSMIVTAGPTVESIDPVRYLTNRSSGKMGYS
                     IAREAIARGADVTLISGPTNLSIPQNLKKFVQIESAQDLYEAVVSNLSENKIVIQSAA
                     VADYKPKTYSDKKIKKKNDDLSIELSRNYDIAYEIGKIKEDKILIGFAAETNDLIEHA
                     KGKIKKKNLDFIVANDLTKEGAGFRADTNIVKIIDVEGNIIEYPKMKKEEVANVILDK
                     VKALLEK"
     gene            complement(29824..30090)
                     /gene="rpoZ"
                     /locus_tag="KRH23_001964"
     CDS             complement(29824..30090)
                     /gene="rpoZ"
                     /locus_tag="KRH23_001964"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed RNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HHS5225244.1"
                     /translation="MLKPSINEVLEKIDNRYYLVGTVSKRARKLIDGEEPYVSNKTKE
                     KPVCVATKEVASGKITYRLLTEEEIEIEEARHHAEQHQQISEEE"
     gene            complement(30093..30710)
                     /gene="gmk"
                     /locus_tag="KRH23_001965"
     CDS             complement(30093..30710)
                     /gene="gmk"
                     /locus_tag="KRH23_001965"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004385 - guanylate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006163 - purine nucleotide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HHS5225245.1"
                     /translation="MFVKKGLLLVVSGPSGAGKGTICKELLKENDTIKLSVSATTRKP
                     RTGEVDGVNYFFISKEKFEEMIEKGEFLEYAQIYDNFYGTPKAAIMECLEKGQDVLLE
                     IEMQGAKQIKEVCPEGVFIFVLPPSLEELKNRIVGRGTETEAEIEKRFSCAYEEIKMI
                     KDYDYFIFNEDVKTSAKEIEGIISSEKNKVSRYKNIIIEKFKEEL"
     gene            complement(30740..31621)
                     /locus_tag="KRH23_001966"
     CDS             complement(30740..31621)
                     /locus_tag="KRH23_001966"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YicC/YloC family endoribonuclease"
                     /protein_id="HHS5225246.1"
                     /translation="MAISMTGFGRGEYKDDNYYFLVECKTINHKYSDINIRLPRKISF
                     LEDKVRNLVKNYVKRGRVDLYIKFDLLGKEDVNLNFDEGLASQYIDILKEIKNKFDII
                     DDISVMNVAKFPDIVKIEEKEEDEDLLWSMLNQAVEDALIKLREMRSEEGKKLAEDIA
                     MRCDLLKNHIEEIEKYSSSVVEDYREKLNLRISELLDDPSIIDENRLAQEVAIYADKS
                     SITEEIVRFKSHIGQLKNTIFKDDSIGRKIDFLIQEMNRETNTIGSKSSDINITNLVV
                     EVKSELEKIREQIQNIE"
     gene            complement(31625..32455)
                     /gene="dapF"
                     /locus_tag="KRH23_001967"
     CDS             complement(31625..32455)
                     /gene="dapF"
                     /locus_tag="KRH23_001967"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008837 - diaminopimelate epimerase
                     activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HHS5225247.1"
                     /translation="MKFWKLHGIGNDFIAIDGRFDQINPSDYTALAKKVCHRRFSVGA
                     DGLLVVKDSKVADVEMVYYNSDGSRAAMCGNGLRCFCKFVYDNCIVKKESFTVDTLDG
                     IKDIKINLTNREINSIRVNMGKGSFIAKDVPVLTNKERFVQESIKVLDRELKVTSMLM
                     GVPHTVVIVDELDVDDVCKYGKEIENNKIFPEKTNVNFVKVEDKYNIHVYTWERGCGY
                     TLGCGTGMTASAIVCNLLNMVESSVNVTSQGGTVKIDVGDFSYMTGPAVKICEGILEV
                     "
     gene            complement(32742..33776)
                     /gene="ltaE"
                     /locus_tag="KRH23_001968"
     CDS             complement(32742..33776)
                     /gene="ltaE"
                     /locus_tag="KRH23_001968"
                     /EC_number="4.1.2.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016829 - lyase activity [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="low-specificity L-threonine aldolase"
                     /protein_id="HHS5225248.1"
                     /translation="MRFIDLRSDTVTMPTDEMREAMAKAPVGDSIFRDDPTVNKLEEL
                     AAAKVGKEDAIFLPSGTFGNQLALFTHCLRGQEIIIGKGYHIVTHEVGAPAVIAGVQL
                     RTIDEDESGALNPELVEKAIRRDDIHEPQTGLICVENAYSGGTVVSLDNLREIKKIAE
                     KHNLPVHLDGARLFNAALTLGVEAKEIAKCCDSVMFCVSKGLAAPMGSILAGSKEFIA
                     KARRKQKVMGGGMRQVGIVAAAGIIAIEKMTLRLNEDHENAKYLACELNKIDGIEVNN
                     VNPDISMVFFKMSEDIIKEDVLIKEFFERNIKINKMENGEYRFVTHVDITKEDLDYVL
                     KTLKELIGVC"
     gene            34072..35847
                     /locus_tag="KRH23_001969"
     CDS             34072..35847
                     /locus_tag="KRH23_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1990112 - RQC complex [Evidence IEA];
                     GO_function: GO:0001968 - fibronectin binding [Evidence
                     IEA];
                     GO_process: GO:0072344 - rescue of stalled ribosome
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Rqc2 family fibronectin-binding protein"
                     /protein_id="HHS5225249.1"
                     /translation="MALDGLVIHSIVDELSSKLTGGKIDKIHQPEDDEVIFNIRNNKE
                     NFRLVLSASASNPRVYLTSNYQKENPLKAPMFCMLLRKYIQGGNIVEISQIGFERIIK
                     ISVESLDELKEKTVKNIMIEIMGRHSNIIITHGEENKIIDSIKRVPFSISRVRQVLPG
                     HGYSLPPEQNKLNPLDDISKDLFIKNLEELEGPIFKSIYSKFLGISPIIAKEICYRAG
                     VNQNAIIKDISDEQFDALHKVFCNLFNDINSNKYSPCIIIDKKVDKVVDFSCINLTLF
                     SDLSYINKDSMSRILEDFYRTKDIKDRINQRSSDLKKSISVKLDRLYNKLKKQEEELS
                     ESENADIYKIKGELITSYIYMVEKGMESIEVANFYDENCNDVTIELNKNLTPSENAQK
                     YFKKYNKMKHAKVEISHQISLNKEEIDYLENIILSIENCENLAELQDIKEELAKVGYI
                     KTQKKNSKKDTIPSTKPHEFVSSDGFKILVGKNNKQNDYLTLRLADNDDLWMHTKNIP
                     GSHVIIKCAGKEVPDNTVFEGAMLAAFFSKSKLSSQVPVDYTKRKNVKKPSGSKPGMV
                     IYETNSTIYVTPEEETVAKLKVKSE"
     gene            complement(36062..37714)
                     /gene="cplR"
                     /locus_tag="KRH23_001970"
     CDS             complement(36062..37714)
                     /gene="cplR"
                     /locus_tag="KRH23_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861613.1"
                     /note="Contributes to intrinsic pleuromutilin, lincosamide
                     and streptogramin A resistance; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein CplR"
                     /protein_id="HHS5225250.1"
                     /translation="MLLVKVENLKKYYADKLILNIDKLEILENDKIGLVGSNGQGKTT
                     LLKAILGEIEIDEGYTYLTESYSYISQSENNIETCSHSKEKSLLNAPDKFEEHLSGGE
                     KVKLKIADALSNKKNIIIADEPTSNLDKKSIGVLEDMFKRHEGALLLISHDRRFLDEL
                     CTTILELEDGKLKAYKGNYTDYLMQKDEEVKKADFEYQEYVKEKKRLEKALLYKKALS
                     DGIRKTPKRMGNSEARLHKMGGQTNKKKLDSNVKAIKSRIDKLEVKNKPKVSKEMNIK
                     IQDGMEIISKNLVEVKDMTLKLENKLLLDNVSFKIKRGKKIALLGDNGCGKSTLIKEI
                     LADKNDNIKINNKVKVGYFDQNQSLLDEKKSVLYNTKVNSSFDESFIRINLSLFGFKG
                     DDVYKKVKVLSGGEKVKIALCKIILEDNNFLVFDEPTNYLDIKSMEALEKALINTDKT
                     MLIVSHDRVFVSHICNYIIEIKDAKIREFDCNYDEYIISRNKKTPSRENQIKKENLLV
                     LENRLTTVISMLSIEKDNLKKELYESEYNELLKQINKLKNSF"
     gene            complement(38013..39224)
                     /locus_tag="KRH23_001971"
     CDS             complement(38013..39224)
                     /locus_tag="KRH23_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015851 - nucleobase transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-xanthine permease family protein"
                     /protein_id="HHS5225251.1"
                     /translation="MKKTIMSLQHLLAMFGATVLVPILTGFNPSVAIFCAGVGTLIFH
                     FCTEGKVPAFLGSSFAFIPVILAAKETYGGDLAYAQGGIIVAGLIYIIMSIIVKIVGV
                     NKIKLYFPAQVTGAMIVVIGLNLLPTAFSMASANFVIAFITLAIAILTNKFGRGFIKQ
                     LGILIAVFSGYIICLILRLVDITTITEASLFAIPNFTVPKFSLGAIVIISPVVLAVFM
                     EHIGDMTTNGAVVGKNFIENPGLNRTLLGDGFATIVAGCLGGPANTTYGENTAVLAIT
                     KNYDPSILRRTAIFAILLACVGKFGGFLQSIPGSVMGGISIMLFSMITYVGLKTIRDS
                     SCVESKINILIIAVILLIGLGTTYLSNKGISVGIPITSTVKITGLSLAAIVGIVLNRI
                     LNNQDFKVEEE"
     gene            complement(39508..40041)
                     /gene="pyrR"
                     /locus_tag="KRH23_001972"
     CDS             complement(39508..40041)
                     /gene="pyrR"
                     /locus_tag="KRH23_001972"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HHS5225252.1"
                     /translation="MVEKAQLMDEKAIARAITRISHEIIERNKGVENLVLVGIKTRGV
                     PIANRISKKIEQIEGTKVDTGDIDITLYRDDLEKIHVEPVVKGTYLDFNVNDKTVVLV
                     DDVLYTGRTVRASLDAIIDIGRPKSIQLAVLVDRGHRELPIRADYVGKNVPTSRHEII
                     SVSLLEIDGEDSVTIKE"
     gene            complement(40401..41348)
                     /locus_tag="KRH23_001973"
     CDS             complement(40401..41348)
                     /locus_tag="KRH23_001973"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HHS5225253.1"
                     /translation="MFYFLKVKVGDIMDEVKEFLVLEEEEEVRLDIYLAEQLGDMSRS
                     YIQKIIKDGKVKVNNKVEKARYLVKEEDNIVIEIPEPKVLEVLPQDIPIDIVYEDDDV
                     LIINKPQDMVVHPAPGNYENTLVNGILYHCKDKLSSINGVIRPGIVHRIDKDTSGLLM
                     IAKNNYAHNFLAEQLKEHTITREYEFICYGVVKEDKITVDKPIGRNPKDRLKMAVVKD
                     GKNAITHFEVVERFDKFTHMRARLETGRTHQIRVHALSINHPLLGDYVYGPKETKFKL
                     KGQTLHAKKLGFIHPTTKEYIEFNSELPEYFKEVIKKIK"
     gene            complement(41317..41763)
                     /gene="lspA"
                     /locus_tag="KRH23_001974"
     CDS             complement(41317..41763)
                     /gene="lspA"
                     /locus_tag="KRH23_001974"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HHS5225254.1"
                     /translation="MLYILIIILLIGLDQLSKIWVLNNLVDVSTIPIINNVFHLTYVE
                     NRGAAFGLLQNNQWIFIIVALLATVFGLYYLNTRKVHIFGRLGIILIISGALGNLIDR
                     VRLGFVVDYFDFRIIWEYVFNIADVFVVVGTVFLCIYVLFFESKSR"
     gene            complement(42073..42852)
                     /locus_tag="KRH23_001975"
     CDS             complement(42073..42852)
                     /locus_tag="KRH23_001975"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HHS5225255.1"
                     /translation="MKKIIWGICICLLSIVGVYTYNHNTHNQDSSKEAYSLNDIIKDD
                     YEDVIIKKGNEDEKILALTFDDGPDEDFTPQVLDILKKNDVKATFFVVGEKVEYNKEL
                     LKRQYDEGHEIGNHTFTHINVAKNSYSSVEKEITDTQNIIKSVIGVEPKIFRPPYRAM
                     SKSVCDIIVSKGMNIILWSNLDPRDWSNPGVDAIINTILTKVQNGNIILLHDYNTKRN
                     DKSQTIQALEVVIPKLKERGYKFVTVSELIQHLDKNKQVQK"
     gene            complement(42907..43389)
                     /locus_tag="KRH23_001976"
     CDS             complement(42907..43389)
                     /locus_tag="KRH23_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TraR/DksA C4-type zinc finger protein"
                     /protein_id="HHS5225256.1"
                     /translation="MDTKKYKDKLLKERENLTNLVEDMKDNTLFGDTTKHTSEKYSSG
                     ELSSYDNHIGDMGTDLYMQNMQNSLINHEEGRLYQIDLALSKIENGTYGICDLCHNQI
                     DLERLDILPDTSLCNDCAKKENNLLGDAMQNPDVEDSNFYSEDLTNLTDLNKNGILRD
                     "
     gene            complement(43655..45076)
                     /locus_tag="KRH23_001977"
     CDS             complement(43655..45076)
                     /locus_tag="KRH23_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_process: GO:0015833 - peptide transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbon starvation CstA family protein"
                     /protein_id="HHS5225257.1"
                     /translation="MVSFLGSIVVLIVGYFVYGTFVEKVFGINDKNQTPAIACRDGVD
                     YVPMKWKRIFLIQFLNIAGLGPIFGAIQGALFGPSAFLWIVFGTIFAGGVHDFASGYL
                     SMKNKGTSASELVGLYLGNGAKIAMRIFSVILLVLVGVVFVTGPAGLLKTLTGVNAQI
                     WVGVIILYYIMATVLPIDKLIGKIYPLFGAALLIMAVGVAGGLIIKGYNIPNINLQNM
                     NPNGTPLFPYLFITIACGAISGFHATQSPLMARCVEKESEARPVFYGSMVAEGIIALV
                     WAAAAMSYFHGIPQLNVIFNDGGAATVVNTVSVGLMGPIGGALAILGVVACPITSGDT
                     AFRSARLTIADAMNYNQDAVKNRFLIALPLFAVGVALTFIDFNIIWRYFSWANQTLAM
                     IMLWTGSAYLVKANKNHYITTLPALFMTVVTFSYIMQAKEGFRLPVNISNGIGVIVAI
                     ILGLLFFKKAKHIKEQNNHKLAS"
     gene            complement(45222..45992)
                     /locus_tag="KRH23_001978"
     CDS             complement(45222..45992)
                     /locus_tag="KRH23_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytR/AlgR family response regulator
                     transcription factor"
                     /protein_id="HHS5225258.1"
                     /translation="MRAIIVEDEFPARKELRYFIENKSGIEVVSEFTNGIEVLDFIQE
                     NKIDVIFLDINIPHLDGMLLAKTLNQFKSRPKIVFITAYESYAVDAFSLDVFDYILKP
                     YSEERIISMLNKLEKSEMSDIELSNVNSNLYKYKKEAVNQEIEEITHKISLWKGDKLV
                     VIDIDDIYYCEANERQTFIYTEKEKFILKEGISEVENLINDKTFFRTHRSYIVNLTKV
                     KEIIPWFNNTYILKLKNSDYEVTVSRSKVKEFRLLMHI"
     gene            complement(45997..47199)
                     /locus_tag="KRH23_001979"
     CDS             complement(45997..47199)
                     /locus_tag="KRH23_001979"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HHS5225259.1"
                     /translation="MKTSILIALIEKTSLIVVLFLLITKLKIFKQIFQKEEYSFNDLV
                     CIALVFTFLAIFGTYSGINYMGSIVNTRIISIVSGGILFGPMVGITAGVFSGIHRYFM
                     DIGGITSVPCLLSSILAGVLSGFLYKRIPKQHRVMYGILVGMISESFTILLIYLISYP
                     HSLAIQIIGGIYLPLVVGQIGIGFVISIVEGIEKDKKDIEARNKAEIKALQRQINPHF
                     LFNSLNTIASFIRFSPDKARELIINLSTYLRYNLEYSDNLIDINKEIEQVKSFVEIEK
                     ARFGELLTVSYDIEDVNIKIPSLIIQPLVENAIIHGILESGRAGVVKISIKKLPYSLE
                     NTVRISIEDNGIGISEEIINNVYQDNMPENKIGLYNVHLRLKLMYGRGLNIRRIDNGT
                     LIVFYVKE"
     gene            complement(47787..48788)
                     /gene="trpS"
                     /locus_tag="KRH23_001980"
     CDS             complement(47787..48788)
                     /gene="trpS"
                     /locus_tag="KRH23_001980"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004830 - tryptophan-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006436 - tryptophanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HHS5225260.1"
                     /translation="MSEKKVIFSGAQPSGKMTLGNYLGAIKNWTELQDNYDCYYSIVD
                     LHAITVPQDPKVLRANTIELLAQYIACGLDPEKNTIFIQSHVKEHVELMWVLNTMTYM
                     GELSRMTQFKDKSQKSEANLNAGLFTYPVLMAADILLYQTDLVPVGDDQKQHLELARD
                     LANRFNNRFSPTFVVPEGYYPKGGARVMSLQEPTKKMSKSDLNENAFILLADDSDSIK
                     RKIKRSVTDSLGVVKYDDEQPGIKNLIDIYSNLSKKSVEEIVNMYEGKGYGIFKEDVA
                     EVVSEALRPIREKYVDLLNNKDYLEKIYSMGAEKAEKQARKTLRKVYKKVGFIERRY"
     gene            complement(48811..49509)
                     /locus_tag="KRH23_001981"
     CDS             complement(48811..49509)
                     /locus_tag="KRH23_001981"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008782 - adenosylhomocysteine
                     nucleosidase activity [Evidence IEA];
                     GO_function: GO:0008930 - methylthioadenosine nucleosidase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009164 - nucleoside catabolic process
                     [Evidence IEA];
                     GO_process: GO:0019509 - L-methionine salvage from
                     methylthioadenosine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HHS5225261.1"
                     /translation="MNVIGIIGAMDEEVSILVDLMDIRETIKKASLEFYKGILEGKNV
                     VLVKCGIGKVNSALCAQILISEFKVDAIVNTGVAGALNEKLDVNDIVISTDAIQYDVD
                     TTAFGDPKGVIPRMKTSVFKADERLIDAAYKSSVEEVKTHKVLKGRVVTGDKFINSKE
                     LKEELVNDFGGYCGEMEGGAIAHVCYLNNTPFVIIRAMSDKADGSADVTYDVFVHDAA
                     NNSKDIVLNMLKSI"
     misc_binding    complement(49552..49792)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(49883..51286)
                     /locus_tag="KRH23_001982"
     CDS             complement(49883..51286)
                     /locus_tag="KRH23_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015171 - amino acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HHS5225262.1"
                     /translation="MEKKKIGLWSLVFMNVSALYGIRWIAKSTASSFGLGLGAIPMWL
                     LFSFIYFVPGALICAELASTYQKGDGGLYDWVKEAFGEKYGFLVSWLNWTAKIFWYSS
                     FLTFLAVNVSYTIGNPALADNKMFVLILSLIIFWALSLIATKGISFTKIFTNTGALGS
                     TIPSAILIIFSFVAVFVLKKHDIASTYTIASMTPKLNMDAFVAISAIMFGLAGAETAA
                     NFITEIDKPEKNFPKAILISAGIVASLYVLGSIAITMIIPPDQITASKGVLDALSAVC
                     ASLGIGSWLVQLIAFGIAFSVLGAIVLYIASPIKMLFGSVKKGIFPDSLVEVNEHKIP
                     SKAVILQAIIVTIILLVTTLMPSVDAIYNVLVTMTALTALFPYVLLYASYIKLRKERP
                     DEIRPYTMAKSTSTCLGLAKMVLVVTVVGILLSAAPVMPTFAENVIYEIEMIGGGLLV
                     ILSGLWLWNRYEKKTAK"
BASE COUNT        17182 a         8848 c         5583 g        19876 t
ORIGIN      
        1 agaaattctt caatatgtgt aaggcaaata tatatttcta ttgcaaattt ttgttattta
       61 tgataatata aatatgtttt tagtctttaa atagttatca ttttaaggag gtgtgcgtag
      121 atggcaaaag tatgtagcgt atgtggtaaa ggtaaggttt ctggaaacca agtatcacac
      181 tcaaataaac ataataaaag aacatggtca gctaacttaa gaagcgtaag agcgattata
      241 gatggagctc ctaagagagt aaaagtttgt actagatgtt tacgttctgg taaaattgaa
      301 agagcttagt aaccacgttt aaaagcctac ttccgtaagt aggcttttta atttaatcat
      361 ttttactctt tctcataaat tttaggatta tacttgaaat ccattttggt aattttattg
      421 ttactacttt catcaatact caccccacac tttatagtta aaactatttt aacaaaaaaa
      481 taataatgct ccacatccaa taagtattaa tgcggtaagt gctgaccaaa tccagccagg
      541 aagcaacatt gacagaatta cagccattcc tgttgctaga caaagtattc ctagcaatac
      601 cttagacttg ttatttctca tggaacacct ccacatagaa cctgtatcta taaatatttt
      661 catattcaag tttatgcgac agttttccat tttagaccaa taaacacatt atgtaatttt
      721 aatttttcat actagaatta ttactgaact ccgatataga ttctacaata tccaaaattc
      781 ctttttttct acttaacctt tcaggtccac tatataaaac aactggtata actttaggaa
      841 gtttaaaatt tttatcttct atttcttcaa gacttttttt cataataaaa cttttccaaa
      901 tttgttctct atacgatttc aatcttggga caatttcagt atccatttct gtttgaaatt
      961 ctaacactat ataatgtgat actttgccac ttttagaaaa taccttataa attatatcaa
     1021 cttcttttcc tttatattca catataaaag atgtttctaa ctctatattt ttaagagtta
     1081 attcttttgc tattgagaca cttgtaaaat tttgaatcaa acttaaaaaa ctttctttat
     1141 ctgaatacat tcttctgtac tcttctcgtt tttcattgct tctttttaaa ttcatacagt
     1201 tcctcctaga ctatagaccc tctatttttt agtaaagata gtctataaat tttatttttt
     1261 aattttcatt agtgagtatt gacagttgtg tgtaaaatat ccagtaaaga tattttttta
     1321 tatttttatt aaaagatata aatttttata ttttaatgta ttgacattta cgttgcgtaa
     1381 aagtgtatat ttaatttata ggaggtatta cttatggaat atacagttca aaaattaagt
     1441 aaactagctg gtataagtac tagaacactt agatattatg atgaaatagg tcttcttaaa
     1501 ccacttaaaa taaattcttc aggttatcgt atatatggtc aaaatgaagt taataaactt
     1561 caacaaatac ttttttatag agaattagga attaacttag aaaatataaa aaacattata
     1621 aattcaccaa acttcgatag tttaagtgcg ttaaaagaac accataataa attactagcc
     1681 aaaagaaagc aaattgattt actaatagaa aatgtaacta aaactatagc tctgaaggag
     1741 ggaaaataca ctatgacaga tatagaaaaa tttgaaggtt ttaaagaaaa gatgattgat
     1801 gaaaatgaaa aaaattatgg aactgaaatt agagagaaat atggtaaaga tattatagat
     1861 acatcaaata aaaaacttaa aaatatgtct aagcaagatt atgaaaattg gcaaaaccta
     1921 aatatcgaaa taattagtaa acttaaaaaa gcttttaaaa ctggtgatgc ctctagtgaa
     1981 ctggctcagg aagttgcaaa attacatcat aaatggttga gttacacttg gaacacatac
     2041 tctaaagaag ctcattcctc tctagcacag atgtatgtat atgatgaacg ttttacatca
     2101 tattatgata gagaacaacc tggattagct aagtttttaa gggatgctat agtaatatat
     2161 acaagagata aataatataa aataataaag gtggtgtctc aaaatgaact ttttagttca
     2221 tgagacactc ttttttgtat gaaatcagat atatttttat cattttatca atgaaaaaca
     2281 ggtttctctc tctattttga gacagaatct ttattgtata ataattataa tcaatacaaa
     2341 ataataacaa attatacaaa acttacttat actatttatg ctaaaaacaa aaaatatttt
     2401 attaaagttt ttaaaactta tgtaatataa aaatctatac tatagacttg attatggaaa
     2461 gaaaattatc aaaatcatta caattagata tactatctct aatatcattg tcatgaatta
     2521 tctttaaaag gatatcataa atggagttta tttttatata atcatcttta tttatagcca
     2581 acatcatgat taatttaaca gtagaatctt cactccaata tattggttca tccaatatgg
     2641 aaatacaaat cttagttctt atagagctta attccatagg atgaggtata gctaaaaaat
     2701 catctatatt ggtagaagat aaactttctc tgtaaaatac agattcagca aatgatggaa
     2761 atacaatttc actttgagtt aatttgttgc acatcaactt tataagctca tctttatctt
     2821 tgattttagg attaacaata aataaatttt tatcaaagaa attgtccaaa agattactat
     2881 aaatatggga attattagtg attgacttag atatattctc tatatctttt tttaatagtt
     2941 ttaaatccac taatacaata ggaatactat catgatttaa aggaattgtc gatattatta
     3001 tatctacatc tgacaattca ctagctaaaa attgattaaa tgatagacat tgaagtatat
     3061 ttattttatc atgaaaaact ttgtttaatt gaacctctaa taacctactt gaaccatacc
     3121 ctgaaccaca tactaatact acgtttttac acttaatatt actttgaaaa aatctctcta
     3181 ttccagcacc tatatgcagg gatacatatc caatttcatc ttctgttaaa gagtaaatac
     3241 tatttttaaa aactttttct atagcattta aagttatttc aaatgctaaa ggataattac
     3301 tctttattgt atttataagg ggattcacct tatttaaatt ataagattta gaattgagaa
     3361 ttgatttaaa gtgcagtact aaatcatcaa ataatacact atcatttcta aggtcaaaag
     3421 tatattgatt gttgattact tctaaaattt cttcaacata ctctataatt ttagtatcta
     3481 ccctattgga aacgttatcc aaaagagaac ttttagttat aaaatgatta tatagataaa
     3541 ctctgtctgc ctttgaaata attatagtat atttactctc aatataatta aatatatttt
     3601 caacagttgt attcgattga aaatctgtta aaacaacatc taaaacatta tctaagcagt
     3661 aaccatcaag tattctactt acagtaatag ctaaatggat aataaagttt tttagattaa
     3721 aatctaggaa attgatatta aatttattaa tttcacttaa cactaccctt tgaagctcta
     3781 ttaaatctac attattaaat aattctattt ctctatctgt aattccaatt atatagtttt
     3841 caaaattcct atttatcata ttattagaaa tacatcttcg aatatctatt tccttacctt
     3901 caactttaac tccataatat ggcttagaaa ctaatattaa attatacttt gacaaaatag
     3961 gctttattct ttttatgtca tttagtattg taaatttact cacatacaag ctattagcta
     4021 aatcttctag ttttatatat gtattgttat agagaatata ttttaaaata tattgatttc
     4081 tttctatagg agaatctggt atttcacttg aatccataat atcatcagat attaatgcta
     4141 gatactgttg gtataatgct aaattaagaa tatctatata atatccttct ccttttttta
     4201 ttttaataat agcaccattt ttctctaaag ttccatttat agaagtaata tcatttctta
     4261 tagttctctc actcactttt aaatgattac ttaaagtttt acaagtaatt ttatcatcac
     4321 tttcatttaa taatttaaac aacgtgagca atctcttgtg cataaatatc cccccttata
     4381 gaatttcttc taaattatac tatttacact catataatac aattactcta ataaaattgt
     4441 attataataa tttatttcca cttctatatg gaaattagtt attatcataa tataaatttc
     4501 catgtcgaag tggaaattag ttatatttaa tttaattagg ataatgatta caatataaat
     4561 ataagttaag acattatgaa tggagtggaa aaatatatgg tattacaaga aaaatatata
     4621 tttatagata aagacttaaa aagcaaagaa gaagtattaa attttattgc agatagtgct
     4681 tatatactag gtattacaac taataaagag gctcttttaa aagaccttct aaaaagagaa
     4741 aatgaatttc caacaggaat aaaagatgga tttgcgatac ctcatacaaa aagtgtaaat
     4801 gtaaaggaag cttccatact ctatattaaa acaactaacg agttagagtg gaaaacttta
     4861 gatgatagta aggttagata tgtatttagt ttgttagccc cacataaaaa tgaaggaaat
     4921 atacatttga aaactctatc taaattagcc acatgtttaa tggaggatga ttttacaagt
     4981 gaagttaaaa atgctagtga tgcaagtcat ttagtaaaat atataactaa taaaatgaag
     5041 gaggaataat tatgaaaata gtagcaataa catcatgtat agcaggatta gcacacacac
     5101 ctatggcagc aaaagcttta gaacaagctg catcaaaaat gggtcatgaa atcaaagtag
     5161 aacaacaagg tgctatggga cgagtaaata ctataacaaa agaagaagca caagatgcgg
     5221 actttatact tatagcatct gaccaaacta tatctggaat ggaaagattt gatggtaaaa
     5281 aagtgataaa agtcaaaata ggtatagcgt taaaaaaacc agaagctgtc ttaacaaagt
     5341 gtatagaagc tatttcttaa taaaaaaatc tcactctaat atagaatgag aaaaatcaaa
     5401 aattaaaaaa ttgtctaatg taattataac atattatcaa aaaatataac aaacttatat
     5461 aggaggatta aaaatgagta aaaaaaataa atctctttta agtgaactta agggacactt
     5521 aatgacaggt atctcatata tgttgccact tgtaataggc tcatctttag ttgtagctat
     5581 cccaaagctt acagctttag cagtgggtat aacaagttta gatgcttata aaaatgtatc
     5641 tggtttttat catattcttt acttaatcga acaagttggt tggactggca taggtctatt
     5701 aaatacggta ttagcaggat ttatagcatt ttcaataggt gagaaaccag ctatgggttc
     5761 aggttttatt ggtggactca tagcaagtaa tactaatgca ggattcttag gagcagtaat
     5821 agcaggtttc tttgctgggt atgtttgtaa gtttttaaag aaaaaaatta aaatatctgg
     5881 gtcagcatca ggaatgatgc cacttataac agttggatta actggttttt taatgagtgt
     5941 tgtattagca ggacctttag gaaacataaa tacttcatta aatgcttggg tagctgaaat
     6001 gtgtcaaaat ggaacaaatt cggtggtatt ggctttaatt ttaggtgcaa tgataggatt
     6061 cgatttaggt ggaccagtaa ataaagcagc ttggatggca ggaaatgcat tattgttaga
     6121 gggaatctat ctaccagcga tattggtaaa ctgcgcaata gttatacctc cactaggata
     6181 tggtttagct acattcataa gaaaatcaaa attttccaat gcattagctg aaacaggaaa
     6241 aggcaatata attatgggca taattggaat aacagaaggt gcaattcctt tcactttaac
     6301 aaatccatta aaattagttc ctgttaatat gataggatgc gctttgggtg taggattatc
     6361 agctttgtta ggtgtacatg ctataatgcc tccagttggt ggattatatg gatttatatc
     6421 aataggttct ggatgggctt acttagtagg tgcaatattt ggagctttag taatagcaat
     6481 attatcaaca actttagtag acttcaatga agatgaaact acggaaaata cagaatttga
     6541 tgaaatagag ttagatataa tgtaaattaa aaacttaatt ttagataatt gagaattgag
     6601 tgtactctca attctcaatt aaattttggg aggattttta tgaaaaagac aaaagtacat
     6661 gtagttccac acagtcattg ggatagagaa tggtatttta caacatcaag gtcaaaaata
     6721 tatttaatga aagattttca agatatatta gacatattgg aagaaaaaga agactttaaa
     6781 tactttacta tggatgcaca agcttctctc ttagatgatt atttaaaatg gagacctcag
     6841 gatgaatata gaataagaga tttagttcaa agaagaagat tagttattgg accttggtat
     6901 actcaaacag accaattggt tatatcagga gaatctataa ttagaaacct ttactatgga
     6961 atagatagat gcaatgaatt tggtgaacct atgagggttg gatatgtacc agattctttt
     7021 gggcaatcag ctcaaatgcc acaaatatac agaggttttg gaatagatag ttcattattt
     7081 tggcgtggag tttctgatga tatggtagat acaacagagt ttatatggaa aggttctgat
     7141 ggttcaaaag tattagcagt tcaaatacca tttggttatt actaaggagg taatatacca
     7201 gaagatgatt ctgatttaaa agaatattta aaagatataa ttggaaaact taaggttaaa
     7261 gcttctacta ataacgtata ttttccaaat ggatttgacc aagcaccaat aagaaaaaac
     7321 cttcctgata tattaaaaaa agctaatgaa atagataatg aaaatgaata cgaaataagt
     7381 gatatagaaa actatataga ttcagtaaga aatgaaagaa atgaatttac agagcttaaa
     7441 ggtgaatttt taaatgctaa acatatgaga atacacaaat ccatattctc ctcaaggtca
     7501 gaccttaaaa taatgaataa caaattagaa aattatatta caaatgtact tgaaccatta
     7561 ttaacattaa gttattcact tggaaatgaa taccctcacc tagttataaa agatatatgg
     7621 aaacttatgt ttgaaaatgc agctcatgac agcataggct cttgtaatag tgacacaaca
     7681 aatgaggatg tatacacaag atacaaacaa gccagagatt tgagtataaa tttattagat
     7741 ttgcatatga gacttataag tactcaaatc aaaaataata atgaagaaat aacattaaca
     7801 atattcaatg gattcccaga agtcagaaat gaagttgtag aatttgatac ttatattcca
     7861 ggtcaagatt ttgtgataaa gaataaaaat ggagaaattc ttaattatat aataaaagaa
     7921 aaagaagata ttacaaatta tatattaact caaacaataa gattaaaccc aagtaaaaaa
     7981 atatatatac ccaaaactgt atatagagca aaaattgcac tttcagtaaa agatatacca
     8041 ccaatgggat atactcaact agtttttgaa ttggatacta aaaataaatg tgaaataaaa
     8101 acaagtaatt gcaaagaaat agaaaacaaa tactacaaaa taacagccaa taaaaatggt
     8161 tcattagaaa tattagataa agaatctaat aagacttata aaaaccaagc tgtaattgaa
     8221 gacaatggag atgatggaga ttcatacaac tattctcctc caaggaaaga tatttatgtt
     8281 tcatctttag attctgtatc ttcagtagaa gtgctaaaat caaacattca agaagaaatg
     8341 atagttaaat attcattgac cataccaact tcactggaag aaagggctat aggtaaagtt
     8401 tctgtgaaaa tgccagtaac aatgaaaatc accttagaac ctaaagaaca aataattaag
     8461 tttaatgtta atataaaaaa taaccaagca ctatctcata gagtaagagt tttatttaat
     8521 acagaaatag catctaagtt ttctatagca gatcaacaat ttggaataat acaaagacca
     8581 acagtattag aaaaagacct tgcattgtgg aaaagagaca attactcatg gcaagaaaaa
     8641 cctataacta tcgaaccaat gcaaagtttt gttactttag aggatggaca aagaggaata
     8701 gcattaataa ctggttgtgt aagagaatat caaatagttg gtgataattt agatacaata
     8761 gcattaacac tattcaggtc atttggatat atgggaagag aaaatttact ttatagacca
     8821 ggaagagctt ctggagaaaa aataatagca acaccagatg cacaattact taaagagtta
     8881 aactttgact ttggtcttta catatataac aataaatttg atgaagcaaa tgtagctaat
     8941 acagctaaga gattcttaac acctatacaa atatatgaat atgctgattt tttaaatggt
     9001 agacttatat ttgcattcaa tgacgaaaaa caaatatatg aaaatgaatt tagtttgatg
     9061 aatgtaaata attcaaattt cacagtaagt gcaataaaga aagaagaaaa aggagatgga
     9121 attgtagtta gaatcttcaa tggtatgaaa aatgaggatg ctaagggaag tcttaacatc
     9181 aataaaaatg tcaatgatgc ttatagtgca atgctcgacg aaatctatga taatactagc
     9241 aagcttaaag taaatactaa aactgtagag gtaaattctt tatcacattg taaagtacaa
     9301 acaatagtaa ttaaataata taaaatagct tatacaagat ttcaaaataa attgctagta
     9361 ctatgttaat agtaaagcca gatattatgc tatttataag ctctgtaaca ctaaataaca
     9421 ttttgtaaaa taaaaaggtg aaccttgtat attaggattc acctttttta aataaatcaa
     9481 cattctgttt taaaataaca tttataagct gttttgaaat aatgcttaca aattatttta
     9541 aaacaatacc tataaatttt tatttaaaga atacacataa atatttccag attcttttat
     9601 tctatagact ttataattat taaagaagtc taatctaatt tttgttaaaa gtaattgtaa
     9661 ctttgaataa atcaccatcc acacttatat tcatcttacc accctgtaat tctataaaac
     9721 tttttgctat cgctaaacca agaccagaac cttctgtgtt acgtgattta tctcctctta
     9781 caaatctctc cattatatca tctacactaa aatcaatctc agatgcagac atatttttaa
     9841 gcataatatt tactttatta tctgtttcta aaatatcaat atacactctt gaatttggca
     9901 ttgcatattt gcttatattt attataagat tttcaaatac tctaaatgta cgctgactat
     9961 ctaatggtaa tattattttt tcattagaaa agttattctt tactattaga gatgaatctg
    10021 caagtttgtc atctaattct aaaagtgtct gcttcattag agatacaata tccacattta
    10081 ctatattcaa ataaacatct ccactatttg ccttgcttac ttcaaacaaa tcttctatta
    10141 gatgttgcaa tctttgtgac tttctgtcta atgtatcaat atacaactta cgattttcat
    10201 ctgttatact ttcatctttt aataaatcta tataagtgat tatagatgtt agaggtgttt
    10261 ttaagtcatg tgatacattt gatataagtt ctgttttcat cttttgactc ttaacctctt
    10321 cgtcaacagc ttttttaaat ccagtttgaa tatttcctaa ttcgtctttt ataggattaa
    10381 aaaatcctaa atctttttcc atatttacat ctaagtttcc atctgaaatt ttctttgtaa
    10441 catctaaaag ttgattatat tcatatattg tctttttaga gtaatctgac agtatcttaa
    10501 ataatactac tgaatatatt aatgcgagta ttattccaaa gaaccacata ctacacatta
    10561 taactataat caataaattt attcccaaaa ttgtaactat agttttattt ggcttttctt
    10621 ttagatttat tgttctaatt tgattaataa ctgtttttcc tgcttttttt agccatacaa
    10681 aaaacattcc tgtcacagta tgttttgtaa aatactctct tattccaaca tttaaaatat
    10741 gttttaaaag tattataaat acaaatatta ttgagaatat tacaaaccaa taagttaaat
    10801 tcattaaact taccaatatg ctagccattt tagcacttat gtcattgttt ataaggtact
    10861 ctacataatt cccactcaag gtattactta ttataacagt aggatataaa tctacaagcc
    10921 cctgtataat agcaagagca ataaagagta tctctaacgg tattcttgat aatgtatcaa
    10981 atcctagcaa ctctttagat tttctatatg ggaatgctaa agctacaata acaactatag
    11041 ctaatataat ttttaaaatc attccagaaa tcttataata agaattattt tctacattgc
    11101 ttatatatga aattatacca tcatcaaaat aagtatttcc ataaccatac tctacactat
    11161 cacctttact tattacttta ggtacagcat atactaatgt tatatttttt attggagata
    11221 acttatatga aattgaattt cctcctaaac ttgtatccat taaatcttct cttgctttag
    11281 ataacaacat ttgattaata actttttgat ttactccata agaatccaca atatttactt
    11341 ttccatcttt atcaaaattc attacaacgt agaatctata gttttctttt atatctgtaa
    11401 tctgcttttg tctttcctca tcattcattt ctgtattttt tgactgattt tcatcagaat
    11461 tttcttttga agcatcattc tttgttgtat caagtactcc taattcttta ttatcattaa
    11521 aaaattcaaa attgctttct ttatcaacta aatagtactt taaattcttt cctgacgctt
    11581 taatgaaatg ctcccaattt tcaaagtttt cattaaaatc tgcattaata ctatcatttg
    11641 tatagtaagt ttctgaacca tcataagtat ctttttcttt acttacattt tttatatagt
    11701 tcatagtttc ttcattgata aatagctttg atggttgtat catcttacct tcttgttctt
    11761 ccttcatatt atgatataaa acataacttc ctttatatat actatctaca aagctttcct
    11821 gttcaaatgg attctttgct ccacctttag cacctgcttg tatagtagaa tattgactaa
    11881 tcatacctaa tgatgctgat aacataagta taaaaactat aatagtaact atatatttat
    11941 ctttaaattt tttcaatttt gtatccaaca ccccacacca cctttaaata tttaggattt
    12001 tttgggtcaa tctctatctt ttcccttata ttcctcacat gtaccataac tgtatctgta
    12061 tttacagcat tctcattcca aactctttca tatatttcat cagcagaaaa aactcttcct
    12121 gcatttctca taagtaaact tagtatttta aattctatag gagttgtttt tatatacttt
    12181 ccatcaatac taacttcttt tgtattttca tttaattcta atccgcctat tgcaaacaca
    12241 ctatcgtcac tttctacctt ttgctcttta tttccaacca tgtttagata cttagtgtac
    12301 cttctaagtt gtgaattaac tctagccaat agttctaatg gcttaaaagg ttttgttaca
    12361 taatcgtctg ctcctatatt aagccccatt attttgtcaa cttcctctga ttttgcagat
    12421 agcattatta ctggaaaatt atagttttct ctaagcttca ttgtaagtgt tataccatcc
    12481 attttaggca tcattatatc aactatagct aaatgtattt cttggttttc tatcacctta
    12541 agaccttcta atccattgta tcccttaaaa acattatatc cttgatttaa tagatatatt
    12601 tctatagcat ctgctatctc cttttcatct tctaccacca aaatattata tgaattcatt
    12661 ctaatctcct ttatattaat ttataaattt tctttacata tatgattata caatatgata
    12721 gaagtttttc catttatata tatatttata tcttttgttc tggttatttg tatttaatgt
    12781 ccatcttaga aacctccttc tagtttaaat ttaatatttt ttcattttgt tttatatact
    12841 taatattaaa attaaaaact taagatatta catatacttt tctaaagatt ttctaaagat
    12901 ttaaatatat ttaaaattaa tatacaaaaa aaagtagttc ttattgtatt aattaaatca
    12961 atgatttgaa atataaaatt aatatcaata aaacctactt tttaattttt taaatattta
    13021 tttttaattt attttgtttt taatttactt cgattttaaa atgtccttga cttttatttt
    13081 ataaatgtac atatttcttc tactggtttt ttagatggac tcttcaaatt gtcctctggc
    13141 actccaagag ctaacattgc acctaaaaaa tactctccct tttcaaaacc agtttctgct
    13201 tctaaaacag cttctatctc atctgctgca tagttttgac ttgtcaacca acaagaacca
    13261 tatccaagtt caattgctga tagtgtaaag ttttcaattg cagcacctag actctgcata
    13321 cctggatttc ttataaataa tttatctata gtctccttag gtgcatctat aagctctaat
    13381 tcataatatc ctgatgggtt atataccttt gtaaaaacta atactaaaac tggagctttt
    13441 aagtaaaata gtgtaaagtt tttaacaaat tttctaaatc tattagcctt atccactgat
    13501 actttatcca tttctacaag tatttcttgt tgctttttag ttatcacatc tgctatcttt
    13561 tccattaaat cacggcgttt tataacaaca aaatgccagt tttgaatatt cttgcctgat
    13621 ggtgctgcac ctgctgcttt tatcattttt aaaatatctt catctgatac atcttgattt
    13681 ttaaactttc ttacactttg tcttttaaaa atagtatctt gtaattccat ttttaaatcc
    13741 ccccataact tttttattat tttaatataa tttttaaact catcttattt taatatatca
    13801 tgttctaaca aatctttaaa tgagtctata aaataatcat atacatctac attcccaaac
    13861 ccatatttgg catatataaa aggtatacct acaaacttag cactatttgc atcaccttgc
    13921 gtatcaccaa catagattgg atttattaat ttatttcttt caattataag tttattattt
    13981 tctcctttat gcaaaccagt attaccagga cattcaaaat ctataaaata ctgttctagt
    14041 ttatgtgctt ttaaaaaaga ttctatatat ccagcttgac aattacttac tataaataat
    14101 ttatattttt tagatagtaa tttaagagta tcttctatat catcaaataa tttagctcca
    14161 ttttcagata aatagtcaca ttctttcaaa gaacattcat tcaataaatt cattctttct
    14221 tcttcactta aatttggaaa taaacgattt gctatttcct caaaagaaag ccccataaga
    14281 cttctaaata aatcttttgt gacacttaat tctatttcct tatgctcact taaaacatcc
    14341 tgccagactt tgcatacttc ttcagttgaa tcccacaatg ttccatctaa atcaaaaata
    14401 atactatcta ccacaaaaaa tcccccttat gtcaaagttt attatatatt tataattata
    14461 tactaaaaag cagatacaat cataaatata ttttacttga ttgtatctgc tctacaatat
    14521 aaaaccaatt gtcaaaatca aattttataa atttctaact acaagtacac agccttgctc
    14581 tactttaatc ttacaagaat tactcaacat aacatttgat attccaatag gtacagagta
    14641 tttcatataa taattatcga gagggtattc taagccagta agtgttacac ccttagcatc
    14701 accatttata gctattacag aaatagtgtc ccctgggttt ccatacaatg aaatttcctc
    14761 attttcaact atatacatct cttctttatc agaaagtatc ctagaatata taccatcttc
    14821 ttttaaataa tataatagct ttatatttgc aagagtgtgg tcaatccttc cccctaaagc
    14881 accaaaaaaa tcaatatgat ttgctttaag tgtcttagct aaaaaaagac aaagctctgt
    14941 atcagtctca tcttttttag atggaaattt ttcaaattta acacctttat ttttatagaa
    15001 gtttatcttt tcttcttcta ctgaatctaa atctcctaat atataatctg gcattatttc
    15061 cattttataa gtgtgatttg cccctccatc tgcacatatt atgcagtcat aacattcctt
    15121 aattataata tctcttgtaa cttcgtaatc ttcaatttcg ccatttaaaa caatacagat
    15181 tttcattatt aaatttaaac taattcttca agagaagcat tctttctaaa taaattaact
    15241 gtttcttgaa tgtcatcact tccaaatatt gcagaacctg ctactattac attagctcct
    15301 gcttgtacaa cttcggctac gtttttaggg cttataccac catcaacttc tatatcaatg
    15361 tttaatcctt gactatctat aatagctttt aactctttaa tcttatctaa aacacaagga
    15421 ataaatgatt gtcctccaaa tccagggtta acagacatta ataataccat atctaaatca
    15481 ggtagtacat gtttaatcgt atctactggt gtagctggat taagtactac accagctttt
    15541 attccatgtg attttatatt ttgtatagtt ctatgtagat gaacacaagc ctcctggtga
    15601 acagttatta tatcacaacc tgcttttaca aattcttcaa tatactggtc tggattttct
    15661 atcataagat gagcatcaaa taccatattt atattttctt tctttaaact tttgactaca
    15721 agtggtccta atgtaatgtt tggtacaaag tgtccatcca ttacatcgat atgaagatat
    15781 tcacatcctg cactttctac ttttcttaca tcttctaata attttgcaaa atctgctgat
    15841 aatattgatg gtgctaattt aatcatgttt ctaatacctc ctactattat tttgtcttat
    15901 ttcatgtagc agctgtatat aactatcata tctttcttta gatatttctc catttgtaac
    15961 agcttctttt atagcacaat taggttcatt ttcatgaata cactttgaac caaacttaca
    16021 atcattaaat ttatcaaatt ctataaaata atctttaagt tcaacttcct ctatatcttc
    16081 aagtgcaagg gaactaaaac ctggtgtatc tgcaaccatt ccaccaaatt ctaattttaa
    16141 aagttcagcg tgacgagtag tatgttttcc cctttttatt ttatcactta caactcctgt
    16201 ttgaagttta aaattttcat ctatttcatt taataagctt gattttccaa ctccagatgg
    16261 tcctgcaaac actactacat tttcttttaa ttcttctttt actttatcta tatttaactt
    16321 agtaatatta cttacaggaa tgactttata gccactaagt tcatatatat ttttaacagt
    16381 ttctaatgta tcattatcat ctaaatctgc ttttgtaagg attattacag tttctaaatt
    16441 ttctttttct gccaaaacta taaatctatc taaaagagat aagtttggtt taggattttt
    16501 tattgcgaat actattaatg ctttatctac atttgcaata ggaggtctta taagttctgt
    16561 atctctcctg tcgatttctt ctaagatacc ctttttttca tcttcatcaa caatgcttat
    16621 tttgactcta tcaccaacca aaggtgttat tttctgcttt ctaaatatcc ctctagcctt
    16681 acattcataa ataccattat aagtatctac ataataaaat ccactaatcc cctttataat
    16741 ttttccttct agcatcaaat gcctcccttt ataaaattta tataaacaca tactgtttat
    16801 gagtagtata tcgtgttatt ctttcctatt tttatataat accacatttt ttttaaataa
    16861 caaatcctcc gtttggacta attacctgac cagtgataaa atttgatttg tctgatgcca
    16921 agaaaatagc acaatttgct atatcttctg gagttcctag cctcattaga ggggtttctt
    16981 ccacaagagc gtctatatct tcctcattat atccagataa catgtcagta ttaatgacac
    17041 ctggagctat gctatttact ctaatatttg atggtcctac ttctttagct aatgcctttg
    17101 tcatacctat tatgcctgct tttgttatag aataatgcac ttcacaagag gcacctgata
    17161 taccccagat tgaagatata ttaattatat ttcctttttt ttctgatatc atgtatttta
    17221 aagcaacttg tgaacaataa aagcttcctt ttaaattaat attcatcata ttatcccaat
    17281 cttcatcagt tatatctgta aacaacttat cttgacttac accagcattg tttacaagta
    17341 catccaatcc tccaaattct tttatacaat aatctaccat atcctctaca tcttctctat
    17401 ttgaaatatt agccttaaaa agttttacag aaaaattttt ttcatttaat atagtgtaca
    17461 actctttagc ttcattttct gacttattaa aatttactaa tacattgtaa ccttcttttg
    17521 caaaagcttt agacatagct ttaccaatcc ctctagctcc tcctgtaatt aaaactgttt
    17581 tcttcttcat aaatactttt ctccttatat tataaccaat tcagtatttt atacaaaaca
    17641 aactgccctt taaagaaaat attttctata aaaggacagc tcttatttta ttaatattta
    17701 ttctgtttta ccaatgtttg cgccagttcc tgatgaagtt cctccattat ctcctgagtt
    17761 tgagcctcct gaactatctc cattgtctcc tgagtttgaa cctcctgaac ttcctccatt
    17821 gtctcctgag tttgagcctc ctgaacttcc tccattatct cctgagtttg agcctcctga
    17881 gtttccacca ctatttcctg agtttgaacc tcctgagtta cttccattat tgcctgagtt
    17941 tccaccacta tttcctgaat ttgagcctcc tgaatttcca ccactgtttc ctgagtttga
    18001 accaggttct gttggtgtat tattctctgg tgttgttggt tttttatctg gtactgttgg
    18061 agtctgtgta tttgattttt ctgaaccttt gcttacatat agatttacct catcaccttc
    18121 ctgagctctt gatgagccag cacctggact ctgacttaaa actgtacctt ctttatatat
    18181 tgagctgtat tcatacttaa cagttcccac ttttaagtta ttttcttcaa taagttgttt
    18241 tgcattactc aaagtaagtc ccactacatt aggaacagat gcctgacttg aacctttact
    18301 tacgacaaca tttatagtat cacccttttt gacatttgta cttccacctt caggtgtctg
    18361 tgatattata caattttcat caacttcact attatactct tcacttttta cactcaggta
    18421 taatccttct ttttcaacag cactttgagc ttcttctaat gtcatattta caagattagg
    18481 aacagtcaaa gatttattgc caaaccctcc agcaaataaa aacttatatg ctaagaatac
    18541 ttgagcacac aatatcagta tcaaaacagc cgcaattact tttaatcttc ttctagattt
    18601 tgggctttcc tgttttttct tctttttctt agttctctta cttggagtac tcttaggtct
    18661 ctgattcttt ttagctctca ttatctcttc ctcttcttca tcttcatctt cttcataaaa
    18721 atcatcatag taatcttcat catcatccaa atcagctact tcaacaggct taaccacttt
    18781 ttcaggagct ggttttgcaa gtgttggatt tacaacttta ttaatttcct tttcatcaat
    18841 tttcttagtt gcaaaatcat catattcttt tataaaatct aaatcaatat ttttttctat
    18901 atactctata tcttctatca attcttcagc agtttgatat ctatctgcac tagatttttc
    18961 tgtaagcttt tttattgtag ttcttacact ttgaggaatc ctaacttttt cttctgatgt
    19021 aaagtctata tcatcattaa tgtgttgaag tgctatagaa attggactat ctcccctaaa
    19081 tggaactttt cctatcaaca tttcatataa aactatacct agagaataca gatcagcatt
    19141 attagttaca aatttacctt tagcttgctc tggtgaaaaa taatgcactg aacctattat
    19201 actaccaata ttagtcattg ttgaatttga aacagctttg gctataccaa aatcagccac
    19261 ttttactact cttccttcat ttgatatgag aatattatga ggttttatat ctctatgtat
    19321 aatccccttt ttgtgcgctg cactaagtgc catagctatt tgttttgtta tatctaatgc
    19381 agtatattca tctaatatac cttcatcttg tataatctct tttagattct tcccatctac
    19441 aaactccatt acaatgtagt gaacttttcc atcttcacca acatcataaa catttactat
    19501 atttggatgt gaaagacttg ctactgcttc tgcctctctt ttaaactttg ttagaaattc
    19561 atcatcatct acaaattcag gtctaagtac tttaagtgca acagtcctgt ttaataatct
    19621 gtctttagcc tcatatacaa aggccattcc tccatcacca atcttcctga tgatttcata
    19681 tcgatttcct aaaattgtat ctcccacaat atcaccgtcc taattatact tttatcacta
    19741 taaccgaaac attatcttta ccagaaacat cattggccat acttatcaat tcttcactta
    19801 tattactagt tctctcatat tcataatcta atattaaatc tcttatatct tcatcatcaa
    19861 taaacccagt taatccatct gtcgcaagaa gtattatatc actttttttg atttctttct
    19921 taaaaatatc tacaacaacc atatcatctg ttccaattgc tctagttatt ctattcctct
    19981 gtggatgtct tcttgcctct tcttctgtaa tgacatgggc catcataagt tcttcaacca
    20041 cggaatggtc tatagttatt ttatcaaatt tttcatctgt taacaaataa catctgctat
    20101 ctccaacatt tgccacatat aagacattat tatacactat agccgtaact aatgtagttc
    20161 ccattccttc aaattctata tcttccatag attttttgtg cacaattgag tttacattat
    20221 tataagcctg ttttaatata tcatctatat agtctatttt tacattatca tgttgtaata
    20281 agttttcctt tagaaaatca attatatttt ctactgctaa tttactggcg acttcacctt
    20341 ttttatgtcc acccattcca tcagctatgg caaatattcc tattggacca tgttctgtat
    20401 ctataacttc tccctcacaa tagtcttcat tgttttttct tatttttcct atatgggagg
    20461 cacaactata aaccatacga cttcctcctt acaaattact tgtattttct tctcaattgc
    20521 ccacaagctc cactaatatc agaacccata gacatcctaa ctgtggcagg tatattgttc
    20581 ttctccaaac tatctctaaa tttataaata aatgctttat ctggcttttc atattctctt
    20641 tcttcaactt tatttattgg aattaaattt acatgacata gcataccttt taggagctta
    20701 gctaatgcct ttgcttcttt ttctgagtca tttactcctt ttataagaga atattcaaat
    20761 gtaacccttc tatttgtctt ttttatataa tatctacatg cattcaatat ttcttcaata
    20821 gaataagcat ttgctacagg cataattttt cttcgttctt catcatatgg tgaatgaagt
    20881 gataaagcta aatttatagc tatttctaag tctgccaact catacatttt aggtactatt
    20941 ccacaagttg aaagagttat atgtctatac cctatattaa gaccattttt ttcgttaatt
    21001 atttttaaaa attgttttgt attttcaaag ttatcaagtg gctcaccact ccccatcaat
    21061 acaagatttg ataccctctt accagtatct tcttgaattt taataacttg gtctaaaatt
    21121 tcccatggct ctaagtttct aattaatcca tccattgtag atgcacaaaa attacatccc
    21181 atcctacaac ctacttggtt agaaacacag acagtaactc tactatcata atccatcatc
    21241 acagtttcta ttatatttcc atcatctaat aaaaacaaat atttttttgt attatctacc
    21301 ttagattcta actttaattc tatatctata tgccctatac atgaaacctc ttctaattta
    21361 tttctcaaac tttttggtat attgttcata tcatcaaaag tttttgcacc cttatatatc
    21421 caagagaata tttgacttcc tctaaagggc ttttcatcta tagttttcat aaattcttta
    21481 agttcatctt cagtaaaatt ttttaatact atctttttct tttccattct ctcactacct
    21541 tattctcttt aattttgcta tgaaaaaacc atctatacca tgaatattag gatatatctt
    21601 taaatatcct ttatcttgat tgtctaagtc tacatttact gtatcaattg gaacaaattc
    21661 aaagttgtga ttttcttcaa caaaagaagt aactatattt atattctcca catcttgaat
    21721 tgtacatgta ctatatacta aagttccacc aactttgaca tatttagatg cattttctaa
    21781 aattttcttt tgtatagaag tgatgtcttt taactcttct tctttcttat acttaatttc
    21841 tggtttacgt cttattatac caaaaccaga gcaaggaaca tctgctaaaa cataatcaaa
    21901 tttacttata ctattttcat caatctcaga agcatcaaat ctttctacaa acacattttt
    21961 aagccccaat ctatttacag tagagtttat aagctttagt ttatgctcaa aaatatctct
    22021 agctactact tgaccagtat tgttcattaa agtagctaag tgagtagatt tccctccagg
    22081 agcactacat acatccaaaa caaatgaacc ttcttttgga ttaattactt tccctactat
    22141 catagaactt atatcttgaa ttgtaaataa accagcctta aataattcat ttttttctat
    22201 atttttcatt ttttcgactt taatagcttc ttctaccata ggaactttta aacatacaat
    22261 acccatttca cttaattttt caataagctc ttctctactt attttaagtg tattcgttct
    22321 tatatagata ctaggctttt cattatttgc ttccaacaaa tcttcagcaa attcttgtcc
    22381 aaatttatct atccagtttt ttataatcca agagttatag gaatacttta tagataagta
    22441 ttttacacta tcttcctcag ttatgtccat tatagtctct ttagctctta tttcatttct
    22501 aagaatagca tttatgaaac cagaagattt tttatcatat ttcttagata attttacagt
    22561 ttcattaact gctgcataat ctgatatact atctaaaaat aaaatctgat atgttcccat
    22621 tcttaaaaag attttaacat aagttgacat tttttttacc tttatttttg aaagtttatt
    22681 gattatataa tctaaataat atttattttc tattactcca taaattaact ctgttgcaag
    22741 tcctctatcc atatcactta tttctaaatt tttaaaatgc ttatttattg caatatttga
    22801 ataattgtca tttttttcta tatcacataa tactttaaat ccaacttctc ttgcatccat
    22861 ataaatttct cccttttatt aaacataaaa aagggttgtt tctaaacaac ccactttact
    22921 tttagtcatt tcttctttga gctattagta acaatctaag taattgaagt attgaaacca
    22981 atgctgctgc aacatatgtt aaagctgctg ctgaaagtac tcttctactt tgtcttgact
    23041 cactttcatc tataatccct aaattcccaa gttgaacgat tgctctactt gaagcattaa
    23101 attctacagg caatgttatt atttggaata acactgaagc cgaaaacaat agtataccaa
    23161 tttttaaaaa tggaccagcc ataataaatc ctaaaaatat taaaaaccaa gatatacttg
    23221 aagcaaaatt cactactggt actaaactac ttcttatttg aagaggtgca taacctttag
    23281 catgttgtat ggcatgacca cactcatgtg cagctactgc aacagaagtt atagatgttc
    23341 cataatatac atcttctgac aaccttacag cctttcttct tgggtcataa tggtcactta
    23401 gatgccctct aaccatttct atctttacat catacaaacc atttgaatca agtactcttc
    23461 ttgctgtttg ctctccagta tatcctcgac gtgtatttac tcttaaatac ttatttgttg
    23521 ttgaactcac tttaaattgt gcatatatag taagtaatat agctggaatt aatataacca
    23581 ttgttgggtc aaatccccaa aaaccgccat atacagggta cataaataac actctcctaa
    23641 aatatatttt tattatacat cctcttaata ttcacttaac ttaaaaacag tttaattaca
    23701 aactaatata ttttttcctg ttaaaaagcc tatagctttt tcaatatcca tcatgtctac
    23761 attagtattt acacaaggtc cattaggtct tttgttaaat acacctaaaa caggaatttt
    23821 cttaatatct tgtattccag atgtcaaatc tctttcacat gcaacagcta caacagcttt
    23881 aggtttagtg tccattataa tttttctagc tagggttcct ccagtagcta caaatatttt
    23941 tacattagtt ttttccttta gcttaattaa ttctcctacg ttgcatcttc cacattcttt
    24001 acaattatct atatcattag taacttttaa tttacaacta ttctcttgaa tacaatgagg
    24061 tattaaaatt attatatcct ctggattaaa attatattta ttactgtata tatattcatt
    24121 atttaacttt atatatattc ttctaatatc actttttgac ataccaaatg atgatgcaat
    24181 gaaagatata ataggaaata atccactgac aatattaaaa tttattttca ttatatttga
    24241 gttaacatac tttcctttaa ttactctata agtaactgct gttgaacata gtattataag
    24301 tattagtgat attattataa tatttatcat caaggagaat atttgagtta aacttattat
    24361 aaaaaaatta acaactccta tcaaaattcc taatattaaa atcaaaatcc caacacttgt
    24421 taaatacttc tttatatctg tcatactttt cacctaaccc aatactaaac cagtttctat
    24481 agtattccct tttatatatt caccaaccaa cattctcttt ttattcggca tctgaatttc
    24541 ttcaattaaa agtacattat ctatagtact tacttttatc ccatctttgc ttacatcaat
    24601 tattgtacct acatcttttg tgcttttttc atctaacact ttagttttcc aaactttcat
    24661 tatgacatca ttataggtag tataagcact tggccatgga tttactcctc taactaaatt
    24721 gtgtatttct ctggcacttt ttgaaaaatc tatgttacct aaggatttat tcattattgg
    24781 cgcataggaa aattcttcat gattttgtac ttctcttgga gcatttcctt cttcaattaa
    24841 tcttaatgtt tcttttaaag tttctgctcc tatattcatc attttatcat gaagttctcc
    24901 tgctgttata ttttcatcaa gatttacttc tgtctttagt atcatatctc cagtatctaa
    24961 tccttcatcc atatacatag ttgtaacacc agtcttttct tcaccattta ttattaccca
    25021 atttataggt gccgcacctc tatattttgg aagtaaagaa acatgaacat ttatacatcc
    25081 aagtttagga atctctaata tttcttttgg aagtatctgt ccaaaagcta caactactat
    25141 tacatctgga tttaaagatt taattttatc tataaattct ttatctctag cctttactgg
    25201 ttgatataca ggtatattat tttcaattgc cagttctttt actgagctca tacctagttt
    25261 tttacctctt ccttttggtt tatctggttg agttacaaca cccaatattt catacttctc
    25321 atctattatt ttttgtaaac atggaactgc tatatcagga gttcccataa atactatttt
    25381 catcaaatca actcctacta cttttctatt ttgtcaacaa ataaaattcc atctaagtgg
    25441 tctatctcat gacaaaatgc tctagctaaa agttcttctc cctctaactc tattgtttca
    25501 ccatttctat ttaaagctct gacctttaca taatttggtc ttctaacatt tcccgcttct
    25561 ccaacaacac ttaaacatcc ttcctcatct atttgctccc cagatgtttc tattatttca
    25621 ggatttataa gttctataag ctcttctcca atatctatta ctactactct ttttaatatt
    25681 ccaacttgag gtgcagccag tccaacacca tctgcatcat acatagtttc tgccatatca
    25741 tctaataatt gtattatctt ttcatcaatt ttttcaacct tttttgattt ttttcttaat
    25801 actggttctc ctatttgaac tatttgtctt aaagccatta taattcctcc taaatttata
    25861 atacactgtt tggattaata tctatagata cattgatatt cttatcaaat atcaaatctc
    25921 gttttgttat acatatatat tttattatac cctttaagag attaatttca atattttcat
    25981 ctttaaagag tatttgccat ctataatttt gatttatttt tgatattgaa catggatttg
    26041 gacctaatat aaatcctaaa tcatttatac cccttttttc taataaataa atcaatgatg
    26101 catgcatatt ttttatattt tttatcacta atctttcatc ttcaccacta acaactacac
    26161 ttaacatatt attaaaagga gaatatccaa atgcttttct tatttttatc tcatcttcat
    26221 aaaaaccctc ataatcatat tcaatagcat gcttaatagc atagtgttca gtgtcataag
    26281 tctgaagtac tacttttccc tctttatcag ctctccctgc tcttccagag acttgagtta
    26341 tcaattgaaa tgtagtttca aaacttttaa agtctggaaa atttaatatc atgtctgcag
    26401 acaaaatacc tactaaagtt acattctcaa aatccagccc tttacttaac atctgtgttc
    26461 caataagtac atctgcttct ttatctttaa atttatttag tatctcatct aaagcacctt
    26521 tttttgaagt tgtatcttta tccattctca aagtttttat atctggaaaa atatatttta
    26581 attcctcttc aattttttga gttccaactc caaatggctt aacataagta cttttacatt
    26641 caggacactc ttttggaatt tctttctcat atccacaata gtggcatctt ccagtattac
    26701 ttttcttatg ataagttaaa gatatatcac aattttcaca ttgaaacaca tatccacact
    26761 ttctacaaga tacaaaattt gcataacctc ttctgtttaa aaatagtatt acttgattat
    26821 tttcttcaat cgcataacgt atttcttttt gtaatttcaa actaaatata cttctatttc
    26881 ctttatctaa ctcatctttc atgtctacaa cttcaatgtt tggaagaggc ttatcatttg
    26941 ctctactttt tatatttata agtttgtatt ctccagattt tgccctataa tactcttcaa
    27001 ttgagggcgt tgctgaacct aaaataagag ttatattatt ttttaatgcc ataaatctag
    27061 caacttctat agcattaaat tttggattct tctcagactt atatgatgac tcatgacatt
    27121 catcaattat tattaagcct aaggaattaa aaggtgcaaa taaagctgac ctagctccaa
    27181 ttaacactct tactttacct gctttaacag ctttgtaaac atcatgtttt tctccttcag
    27241 atagtttact gtggaacact ccaactaaat ctccaaacct actctttagc ctatctattg
    27301 tttgaggagt taatgctatc tcaggtacta agaatatact gtctaagcct tgatttagag
    27361 caaattctat tatttccatg taaacttcag tttttccact tccagttact ccatgaatta
    27421 agtatggttt tttatcatct acaaacatat tcgactttat ctcatcaact gcttcttgtt
    27481 gctcattgtt taattttata ctttttagta cggatttgta aatacttttt ggctctctat
    27541 aataatcctt aaattctagg gttattagct ttttcttact tagagaattt atactttgtt
    27601 ttgaagcatt taataaatcc aataaatcat ttatctctac attttcatta tttttaagaa
    27661 aacttaatat ctctttttgt ttacttccca catttatttt attttgctct atataatcgt
    27721 caatcttatc actttctaaa ctcaaagata tataacatac tttcttttca tttttgtgat
    27781 ttttatattc ccaacataat tttataattc catttttatt cattgtgtac aaagaactat
    27841 ttaagtttgg tatatatttt aacttatcaa ccttaatttt acctttacta tcaatcactt
    27901 tctctactat ttctctattt ttatcactta aagttgatat tttttccttc aattcaatat
    27961 catttaatcc acttaaactt tcacctaata ggactacttt ataattattt aatttgtatc
    28021 cctttggata tatcaaattt atacattcta tataagtaca caaatatcta tttttcatcc
    28081 aataaaccaa ctctaaatct tcttttctaa atatcggatt ttcatctaat atatcaataa
    28141 tttcttttat ttttattttt tcatctaagc tatctgtaaa ttgaaataca aaggcttctg
    28201 ttggtttatt accttttcca aatggtacta atattctgtg cccaattttt attacatcag
    28261 ataaaaatac aggaatttga tatgtaaata aattatctgt atatatagta ttacttctaa
    28321 ctattacctt tgcatatttt ttcattataa aacctctact taaatttaat atattgttca
    28381 tattttaata tactttacaa gatattaaaa tctcagaatt tataagcaat ttcaagttat
    28441 taatattatc tttattttaa taattaacta ttaattatat tttatacttt atgacaaaat
    28501 aaatgctgaa aactacaatt taactgacat ttgcgagttt ttactcgcta aaattaaatt
    28561 gcagctttca gccactttag ctgtgataaa atacacaaat atcatattta aaaaaggtct
    28621 tatttctcaa gcaacgcttt aactttatct aaaataacat tggctacttc ttcttttttc
    28681 atcttaggat actcaataat atttccctct acatctatta tttttacaat attagtatca
    28741 gctctaaaac cagcaccttc tttagttaaa tcatttgcca caataaaatc taaatttttc
    28801 ttttttattt ttcctttggc atgttctata aggtcattag tttcagctgc aaatccaatt
    28861 agtatcttat cttcttttat ttttcctatt tcataagcaa tatcataatt tctacttagt
    28921 tctattgata aatcatcatt cttcttttta atttttttgt cagaataagt ttttggttta
    28981 taatctgcaa ctgctgcact ttgaattact attttatttt cacttaaatt tgatactact
    29041 gcttcataca aatcttgtgc tgactctatt tgaacaaatt ttttaagatt ttgtggaata
    29101 gaaagatttg taggacctga tattaatgtt acatcagcac ctctagctat agcttctctt
    29161 gctatagaat atcccatttt accagaagac ctattagtta aatatcttac tgggtctata
    29221 ctctctacag ttggaccagc tgtaactatc atactttgac cttttaaatc ttgctcttta
    29281 gtaagattag tcaaaacttc ctctactatt atatctggat tagctagttt acctgttcca
    29341 atatctccac atgcaagcct tccactttcc ggttcaataa atttatatcc aaagctcttt
    29401 aaagtttgta tatttttttg aacaattgga ttttcataca tattagtatt catagctggt
    29461 gctataagaa cctgtgcttt tgttgccata acagtagttg tcaacatatc gtcagctata
    29521 ccatttgcaa tcttgcctat aacatttgca cttgctggca ctattaagaa taaatctgct
    29581 ttttttgcta atgatatatg ttcaacttcc caagtttttg gttcttcaaa catatcttct
    29641 actacataat tttgactcag cgattgaaat gtaagtggtt taacaaattc tgttgctgat
    29701 tttgtcatta taacatggat atttgcattt agttttttta acttacttac aacatcacaa
    29761 gccttatatg cagctatacc gccacttatg ccaattacaa cagttttatc ttttagcatg
    29821 accttactcc tcttctgaaa tttgttggtg ttgctcagca tgatgtctag cttcttctat
    29881 ctctatttcc tcttctgtca ataatctata tgttattttt ccacttgcaa cttctttagt
    29941 tgctacacat acaggctttt ccttagtttt atttgaaaca tatggttctt ctccatcaat
    30001 taattttctt gctctctttg aaacagtccc tactaaatag tatctgttgt ctattttttc
    30061 tagtacctca ttgatagatg gttttaacat aattataatt cctccttaaa tttctctatt
    30121 ataatatttt tatatctgct aactttattc ttttcagatg atattatacc ttctatttct
    30181 ttagcagatg tttttacatc ttcattaaat ataaaataat cataatcctt aatcatttta
    30241 atttcttcat atgcacagct aaatctcttc tctatttcag cttctgtttc tgtacctctt
    30301 ccaacaattc tattttttaa ttcttcaagt gatggtggta gtacaaatat aaatactccc
    30361 tctgggcaaa cttcttttat ttgttttgct ccttgcattt caatctccag taatacatct
    30421 tgtccttttt ctaaacattc cattattgcc gcttttggag ttccataaaa attatcataa
    30481 atttgagcat actccaaaaa ctcacctttt tctatcatct cttcaaactt ttccttactt
    30541 atgaagaaat aatttactcc atcaacttct ccagttctgg gttttcttgt agtagctgat
    30601 acagaaagtt ttattgtatc attttcttta agtagttctt tgcaaatagt accttttcct
    30661 gcacctgatg gtcctgatac aactagcaat aatccttttt tcacaaacat ttaagcattc
    30721 cccttctaat attgtattct tactctatat tttgtatttg ttctcttatt ttttccaatt
    30781 cgctttttac ttctactact aaattagtta tatttatatc agatgacttc gaacctatag
    30841 tgttagtttc tctattcatc tcttgtatta agaaatctat ttttctacct atagagtcgt
    30901 ctttaaatat agtattttta agttgcccta tatgactttt aaatctaact atttcttctg
    30961 ttatactgct tttatctgca tatattgcaa cttcttgtgc taatctattc tcatctatta
    31021 tacttgggtc atccagtaat tcacttattc tcaaattcaa tttttctcta taatcttcta
    31081 caacactact tgaatatttt tcaatctctt ctatatgatt ttttaataaa tcacatctca
    31141 tggcaatatc ttcagctaat tttttacctt cttcacttct catttctctt aatttgatta
    31201 atgcatcttc aactgcttga ttcaacattg accacaataa atcttcatct tcttcctttt
    31261 cttctatttt cacaatatca ggaaactttg caacattcat aacgctaata tcatctataa
    31321 tatcaaattt attttttatt tcttttagta tgtctatata ctgagatgct aatccctcat
    31381 caaaatttaa gtttacatct tctttgccta ataagtcaaa ctttatgtat aaatctactc
    31441 ttcctctttt tacataattt tttactaaat ttctaacttt atcctctaaa aatgaaattt
    31501 ttcttggaag acgtatgttt atatctgaat acttatgatt tatcgtttta cactctacta
    31561 aaaagtaata attatcatcc ttgtattctc ctcttccaaa accagtcata cttatagcca
    31621 ttaattaaac ctccaaaata ccttcacata tttttactgc tggacctgtc atataagaga
    31681 aatctcctac atctatttta actgttccac cttgagacgt tacatttaca ctactttcta
    31741 ccatattaag taaattgcac actattgctg atgcagtcat accagtacca caacctaaag
    31801 tatatccaca acctctttcc caagtataaa catgtatatt atacttatct tctaccttta
    31861 caaaatttac attcgttttt tcaggaaata ttttattatt ttcaatctct tttccatatt
    31921 tacaaacatc atctacatct aattcatcta ctataactac tgtatgagga acccccatca
    31981 acatagaagt aactttaagc tccctatcta aaacctttat actttcttgc acaaaacgtt
    32041 ctttatttgt aagtacagga acgtctttag ctataaaact tccttttccc atattgactc
    32101 ttatagagtt tatttctcta ttggtaagat ttatttttat atcttttata ccatctaatg
    32161 tatctactgt aaaactttct tttttaacta tacaattatc ataaacaaat ttacaaaaac
    32221 atctaaggcc atttccacac atagctgctc ttgaaccatc agaattataa tataccattt
    32281 ctacatctgc aacttttgaa tctttcacaa ctaacaatcc atccgctcct acagaaaatc
    32341 ttctatggca tacttttttt gctaaagcag tataatcaga tggatttatc tggtcgaatc
    32401 ttccatctat tgctataaaa tcatttccta ttccatgtag tttccaaaat ttcataagta
    32461 tcgctccttc gtaaattaac gcttaaacta ttataacata aaaaaattcc cataaactta
    32521 taatttatgg gaaaagtttt gtaatgacaa ctataatttg aggatgtgag ggagagttgc
    32581 cattacaatt agggtaatta tattatgttt ttaagctagt tctttctatg tttatatatt
    32641 aatatttcta tatgaatttt atgtatgttt tatttaaact gtctatgaat tttttaatta
    32701 aacatctggt aactagctat aatccttcta gtagatatct attaacatac acctattaat
    32761 tctttaagtg tttttaaaac atagtctaaa tcttccttag taatatctac atgagttaca
    32821 aatctatatt caccattttc cattttatta atttttatat ttctttcaaa aaattctttt
    32881 attaaaacat cctcttttat aatatcttca ctcatcttaa aaaataccat acttatatct
    32941 ggattaacat tgtttacttc aatgccatca attttattta attcacaagc taaatatttt
    33001 gcattttcat ggtcttcatt caatcttaaa gtcatttttt caatggcaat tataccagct
    33061 gccgcaacta tacctacttg tctcattccc ccacccataa ctttttgctt tcttctagct
    33121 tttgctataa attctttact tccagcaagt atagaaccca ttggtgcagc taaacctttt
    33181 gacacacaga acataacact atcacaacac tttgctattt ctttagcttc tacacccaaa
    33241 gttaatgctg cgttaaataa tcttgctcca tctaaatgta ctggtaagtt atgtttctca
    33301 gctatttttt taatttctct taaattatca agactcacaa ctgttccacc tgaatatgca
    33361 ttttctacac atataagccc tgtctgtggt tcatgtatgt catctcttct aattgccttt
    33421 tcaacaagtt caggatttag agctccactt tcgtcttcat ctatagttct aagctgaact
    33481 ccagctatta cagcaggtgc cccaacctca tgagtcacaa tgtgataacc tttaccaata
    33541 attatttctt gccctcttag gcaatgagta aatagagcta attgattccc aaaagttcca
    33601 cttggaagga aaatagcatc ttcttttcca actttagctg ctgctaattc ttcaagttta
    33661 tttacagtag ggtcatctct aaagattgaa tctccaacag gagcctttgc catagcttct
    33721 ctcatttcgt cagtaggcat agtaacagta tcacttctta aatcgataaa tctcattttt
    33781 tcaaccttct ttcatattta tatactatag aaccttaaaa ttgatttttt ctgtaaagtt
    33841 catatacttt catagcttat actctacaca ataattatac tatatttact ttatatttaa
    33901 tctactttaa attattaatt ttaaaaataa agtttcctct ctaataagta taaataatta
    33961 tacaatttaa atattaatct ctattgttta aattccccct agtcacaaag cgtatattat
    34021 gtgtataatt aatttactga ctcattttgg tcaaagaaag gggtgctata aatggcatta
    34081 gatggattag ttatacattc aatagtcgat gaattatcat caaaacttac aggtggaaaa
    34141 atagataaga tacatcaacc tgaagatgat gaggtaattt ttaatataag aaataataaa
    34201 gaaaatttta gattggtttt aagtgcaagt gcctcaaatc ctagagttta tcttacaagt
    34261 aattatcaaa aagaaaaccc tctaaaagcg cctatgtttt gtatgttact tagaaaatac
    34321 atacaaggtg gaaatatagt agaaatttct caaataggtt ttgaaagaat aataaaaata
    34381 agtgttgaat ctttagatga attaaaagaa aagacagtta aaaatattat gattgaaatt
    34441 atgggaagac atagcaacat aataataact catggtgaag aaaataaaat tatagattct
    34501 ataaaaagag tcccttttag cataagtaga gttcgtcaag ttttacctgg tcatggttat
    34561 tcattaccac cagaacaaaa taaactcaac cctcttgatg atatatctaa ggatttgttt
    34621 attaaaaacc tagaggaatt ggaaggacct atctttaagt ctatatattc taaatttcta
    34681 ggtataagcc ctattatagc taaagaaatt tgctacagag caggtgtaaa tcaaaatgct
    34741 atcataaagg atatatctga tgaacaattt gatgctttac acaaagtatt ttgtaattta
    34801 ttcaatgata taaattctaa caaatactct ccttgcatta ttatagataa aaaggtggat
    34861 aaggtagttg atttcagttg tataaacctt acattattta gcgatttatc atatataaat
    34921 aaggatagta tgtctcgtat tctggaagat ttctatagaa ctaaggatat taaagataga
    34981 attaatcaac gttcatctga tttaaagaag agtatatctg ttaagcttga tagactttat
    35041 aataaactta aaaaacaaga agaagaatta tcagaatccg aaaatgcaga catttataag
    35101 ataaaaggag aattgattac ttcatatatt tatatggtag aaaaaggtat ggaaagtatt
    35161 gaagttgcta acttctatga tgaaaattgt aatgatgtaa caatagaatt aaataaaaac
    35221 ttgacaccat ctgaaaatgc tcaaaaatac tttaaaaagt ataacaaaat gaaacatgct
    35281 aaagtcgaga tatctcatca aatttcctta aataaggaag aaatagatta cttagaaaac
    35341 ataattttaa gtattgaaaa ctgtgaaaat ttagctgaat tacaagatat aaaagaagaa
    35401 cttgctaaag ttggatacat caagactcaa aagaaaaaca gtaaaaagga tactatccca
    35461 tctacaaaac ctcatgaatt tgtgtcttct gatggattta aaatattagt tggtaaaaac
    35521 aataagcaaa atgactatct tacactaaga cttgctgata atgatgactt atggatgcat
    35581 acaaagaata ttcctggttc tcatgtaata ataaagtgtg ctggtaagga agtccctgat
    35641 aatactgtat ttgaaggagc tatgctagca gcattcttta gtaagtcaaa actttcttct
    35701 caggtgcctg tagactatac taagagaaaa aatgtgaaaa aacctagtgg ttctaaacca
    35761 ggtatggtta tttatgaaac taacagtact atttatgtta ctcctgaaga agaaacagta
    35821 gccaagctta aggttaaatc tgaataaatt ctgcactaaa tacaaaataa atgttagaca
    35881 actacacatt atcattctaa ataaaaatag tggccttctt ataaagtaca ataataaggc
    35941 cactttctaa ttagcttact tttaattttc taacaaaata cttttctgtt ttaataacta
    36001 tacttatatt cccaacaaat attttcagtc ttcttatata gatgtaatta aaaagttaac
    36061 actaaaagct attttttaat ttattgattt gttttagtaa ttcattatat tctgattcat
    36121 acaattcttt ttttagatta tctttttcta tagataacat agatataaca gttgtaagtc
    36181 tattttctaa tactagaaga ttttcttttt tgatttggtt ttctctacta ggagtttttt
    36241 tatttctgct aattatatat tcgtcataat tacaatcaaa ctcccttatt ttagcatctt
    36301 ttatctctat aatatagtta caaatatgtg atacaaatac tctatcatga gacactataa
    36361 gcatagtttt atcagtattt atcagtgcct tttccagtgc ttccatagat tttatatcta
    36421 agtaatttgt tggttcatca aatactaaaa aattattatc ttccaatatt attttacata
    36481 gtgctatttt taccttttct ccaccactaa gtacttttac ttttttgtag acatcatcac
    36541 ctttaaaccc aaataggctt aagtttatcc ttataaaaga ttcatcaaat gaactattaa
    36601 ctttagtatt gtatagaaca ctctttttct catctaataa actttgattt tggtcaaaat
    36661 aacctacttt taccttgtta tttattttta tattgtcatt tttatcagcc aatatttctt
    36721 ttatcagagt actttttcca cacccattat cacctaataa tgctatcttt ttacctcttt
    36781 ttatcttaaa agaaacatta tctaacagga gcttattttc taactttaga gtcatatctt
    36841 ttacctctac tagatttttg ctaattatct ccataccatc ttgaatctta atgttcattt
    36901 ctttagaaac tttaggttta ttctttacct caagtttatc aattctgctt tttatagcct
    36961 tcacatttga gtccaacttt ttcttattag tctgaccacc cattttgtgc aatctagctt
    37021 ctgaattacc cattcttttt ggtgtttttc ttatgccatc acttaaagct tttttatata
    37081 aaagagcctt ttcaagcctt tttttctctt taacatattc ttgatactca aaatcagctt
    37141 tttttacttc ttcatctttt tgcattaaat aatcagtgta attgcctttg taagctttta
    37201 gttttccatc ttctagttct aatatagttg tacataactc atccagaaaa cgtctatcat
    37261 gagatattaa taataatgct ccctcatgcc ttttaaacat atcttccaaa accccaatgc
    37321 tttttttatc taagtttgaa gttggctcat cagctattat gatatttttc ttattactca
    37381 gcgcatctgc tatttttaac ttaacctttt cccctcctga taagtgttct tcaaatttat
    37441 ctggagcatt taaaagactc ttctccttac tatgactaca tgtttcaata ttattttcac
    37501 tctgacttat ataagaatag ctttctgtaa ggtaagtata tccttcatca atttctattt
    37561 ctcccaatat tgcttttaat aatgttgttt ttccttgacc atttgaacca actagaccta
    37621 ttttgtcatt ttctaatatt tcaagtttat ctatattcaa aattaattta tctgcataat
    37681 atttctttaa attctctact tttactaaca acataaaaaa tccctcctta acacacttaa
    37741 atataaggag agattctata aataggcata acaaataaac gtatagacta taatctactc
    37801 tccttaattt aagcattgca aataaagcca ccaaaatagg cttttcaaaa attacaatac
    37861 tttaaattat aaaaaataga ttatattctc attgtcctag ttaccttgcc ctttctttca
    37921 tttattttta atcattatat caacattaat tacaaatgtc tatagaaaat taactaattt
    37981 tagttattca atatacaact tattctttaa atttattctt cttcaacttt aaagtcctga
    38041 ttatttaaaa ttctgtttaa tacaattcca acaattgcag ctaaactaag accagttatc
    38101 tttactgtac ttgttatagg gattccaaca gaaatacctt tattagataa atatgttgtt
    38161 ccaagaccta ttaataatat aactgctatg attaatatat ttattttact ttctacacaa
    38221 gaactgtccc ttatagtttt taatcctaca taagttatca tcgaaaatag cattatacta
    38281 attccaccca taactgaacc tggtatactt tgaagaaatc caccaaactt gcctacacat
    38341 gcaagcaata tagcaaatat tgctgtacgt ctaagtattg aagggtcata gtttttagtt
    38401 atagcaagta ctgctgtatt ttctccataa gttgtatttg ctggtcctcc taaacaccct
    38461 gcaactatag tcgcaaatcc atccccaagt aatgttctat ttaatccggg attttctata
    38521 aagtttttac ctactacagc accattagta gtcatatctc ctatatgttc cataaataca
    38581 gctaatacaa ctggagatat aatcacaatt gctcctaaac tgaacttagg aactgtaaag
    38641 ttaggtattg caaataaact tgcttctgta atagtagtta tatctactaa tcttaatatc
    38701 aaacagatta tatacccaga aaaaactgct attaatattc ctaattgttt tataaatcct
    38761 ctaccaaact tattagttaa aattgctatt gctaaagtta taaatgctat tacaaaattg
    38821 gctgaagcca tactaaaagc tgttggcaat aaatttaatc ctataactac tatcatagct
    38881 cctgtaactt gtgcaggaaa atataattta attttattta caccaactat ttttactata
    38941 atcgacatta taatataaat taatcctgct actattatac caccttgagc atatgctaaa
    39001 tctccaccat acgtctcttt agctgctagt ataactggta taaacgcaaa acttgaacct
    39061 aaaaaggcag gtacttttcc ttctgtacaa aaatgaaata tcaatgtacc aacaccagca
    39121 cagaaaattg caactgatgg attaaaacct gtcaaaatgg gaactaatac tgtcgctcca
    39181 aacatggcta atagatgttg taaagacatt atcgtttttt tcataaaaac ctccaaaatt
    39241 attatatata aataaatcct ctgtttaatt aatatctttt aattaattat cattccctag
    39301 attctatttt ttaacctcta tatacttatt atataattta tcattatttt acattttacg
    39361 acatcaaaaa ctcaaataaa ggagaataaa aactacatta agactcacat ccataaaatt
    39421 ataatattta ttttgtgcaa tctatgtaag ctttatcctc ctccctgact attcaatgct
    39481 aagcttttat ataatactta aaaataatta ttctttgatt gtaactgaat cttctccatc
    39541 aatttctaat aaactgacag atataatttc atgtctagaa gtaggtacat tttttcctac
    39601 ataatctgct cttataggca actctctatg ccctctgtcc actagcactg ctaattgtat
    39661 tgatttaggt cttcctatat ctataatagc atctagtgaa gctctcacag ttcttccagt
    39721 gtataaaaca tcatcaacta aaactactgt cttatcattt acattaaaat ctaaataagt
    39781 tcctttaact acaggttcaa catgaatttt ttccaaatca tctctataca aagttatatc
    39841 aatatctcct gtatctactt ttgttccttc tatttgttct attttcttag aaattctatt
    39901 tgcaattggc acacctctag tctttattcc aactaaaact agattttcta cacctttatt
    39961 tctttcaatt atttcatgac ttattctagt aattgctctt gctattgcct tttcatccat
    40021 taattgagct ttttctacca tatcataatt attgtcaaag atataatata tctatttgac
    40081 aaatctactc ctttctttta attttttata aatttatttt tatttaaaat ttcaatttaa
    40141 acaacaaaaa aacttctcat cacaagacaa gaagctctta tataaaaaat atacagtgca
    40201 atttagcaat tgtcttacga tatctctgta tcgtttaaag ataatttttt aatctatcaa
    40261 atcaaattat atatttatat ttcaaatttt tcaagctttt ttaaacaaaa tactttaata
    40321 taagatattt tatttaaatt tcactaaatt tatttactta tataaaaaca aaaaatgatt
    40381 tataagtatt atacaaatag ttattttatc tttttaataa cttccttaaa atactcaggt
    40441 aattctgaat taaattcgat atattcctta gtagtaggat gtataaatcc caacttctta
    40501 gcatgcaaag tttgtccttt taatttaaat ttagtttctt ttggaccata tacataatca
    40561 cctaaaagtg ggtgatttat agacaaagca tgaactctta tttgatgagt tctaccagtt
    40621 tcaagcctag ctctcatatg tgtaaactta tcaaatcttt ctacaacttc aaagtgagtg
    40681 attgcatttt ttccatcttt tactacagcc atttttaatc tatccttagg atttctccct
    40741 ataggtttat caacagttat tttatcttct ttaaccacac catagcatat aaattcatac
    40801 tccctagtta tagtatgttc ctttaactgt tctgctagaa aattatgtgc ataattgttc
    40861 ttagctatca taagaagacc agaagtatct ttgtctattc tatgaactat accaggtcta
    40921 ataacgccat ttattgatga caacttatct ttacaatgat ataaaatccc gtttactaac
    40981 gtattttcat agtttccagg agcaggatgg acaaccatat cctgaggttt atttattatt
    41041 aagacatcat catcttcata tacaatatct attggaatat cttgaggtaa aacttctaat
    41101 actttaggtt ctggtatctc tataacaata ttatcttcct ctttaaccag atatctagct
    41161 ttttctactt tattattaac ctttactttt ccatctttta taattttttg tatataactt
    41221 cttgacatat cacctaattg ttctgctaga taaatatcaa gtctaacttc ttcttcctct
    41281 tcaagtacta aaaactcttt tacttcatcc attatatcac ctacttttac tttcaaaaaa
    41341 taaaacatat atacataaaa acacagttcc tacaactaca aatacatcag ctatattgaa
    41401 tacatattcc catataattc taaagtcgaa gtaatctact acaaaaccta atcgtactct
    41461 atcaattaga tttcccaatg caccagatat aattaatata attcccaacc ttccaaatat
    41521 atgtactttc cttgtattaa gatagtatag tccaaatact gttgcaagta atgcaacaat
    41581 tataaatatc cattgattat tttgtaataa tccaaatgct gcacctctat tttcgacata
    41641 agttaaatga aatacattat ttattattgg tattgttgat acatccacca aattattcaa
    41701 tacccatatt ttagacagtt ggtctaaacc tatgagtaga attattatta atatatatag
    41761 caatgatttt tccccctata aattatttaa aaaccaattt tatttgaagc acactattat
    41821 tattatacaa aaaaaatgct ctaaagagca actttattaa aattgtattt tcttaataaa
    41881 gctagaacaa aatttaaaat agtactactt tttttatatt gtagatttct acatatttaa
    41941 aatcatatca ttatgtataa aaaatttaaa aataccatac taatcaatat tttttgtgta
    42001 ttttatagat taaagattaa tgatgtctgt aatttaaact tacaatcacc actaatcttc
    42061 aaacaaatat ttttactttt gcacttgctt atttttatct aaatgttgta taagttcaga
    42121 tactgttacg aatttatatc ctctctcttt taatttagga attactactt ctaaagcttg
    42181 tatagtttgt gatttatcat ttcttttagt gttataatca tgtaaaagta ttatattacc
    42241 attttggacc tttgtaagga tagtatttat aattgcatct actccagggt tagaccaatc
    42301 tctagggtct aagtttgacc aaagaattat attcatgcct ttagaaacta taatatcaca
    42361 gacactttta ctcatggctc tatatggagg tctaaatatc tttggttcta ctcctattac
    42421 actttttata atattttgcg tatctgttat ttctttttca acactactat aactattttt
    42481 tgcaacattt atatgtgtaa atgtatgatt ccctatttca tgcccctcat catattgtct
    42541 ttttaataat tctttgttat attctacttt ttctccaact acaaaaaaag ttgcttttac
    42601 atcatttttc tttaatatat caagtacttg tggtgtaaaa tcctcatctg gaccatcatc
    42661 aaaagtcaat gctaaaattt tttcatcctc atttcctttt tttattatta catcttcata
    42721 atcgtctttt ataatgtcat ttaaactata tgcttctttt gaactatctt gattatgtgt
    42781 attatgatta tatgtatata cacctactat agataataaa catatacata taccccatat
    42841 tattttcttc atgtcattac ctcttttcta attcattcta gcaatatatt ttataatgtc
    42901 agttttttaa tctctcaata ttccattttt atttaaatca gttaaatttg ttagatcttc
    42961 tgaataaaag ttagaatctt ctacatcagg gttttgcatt gcatcaccta ataaattatt
    43021 ttctttcttt gcacaatcat tacataaact tgtatctggc aatatatcca atctttctaa
    43081 atctatttga ttatgacata aatcacaaat cccatatgtt ccattctcta ttttagataa
    43141 tgctaagtct atttgataca atcttccctc ttcatgattt attagactgt tttgcatatt
    43201 ttgcatatat aaatcagttc ccatatctcc tatatgatta tcataactag ataattctcc
    43261 tgatgaatac ttttcacttg tatgtttagt tgtatctcca aataaagtat tatctttcat
    43321 atcctctact aaattagtta aattttctct ttctttcaat aatttatctt tatatttttt
    43381 agtatccatt tttaacacct ctaattttaa tatttatatc ataaaaatag tatgtggaaa
    43441 agtgaattaa acatacaata aaaataagat ttgattcgaa aaatggaatg tctcaaaatg
    43501 aaatttttag ttcatttaac cctctttttt atatgaaatc aaacatattt ttatcctttc
    43561 agcaataaaa aagagactta tctctatttt gagatagtct cttctttgaa cataatttaa
    43621 atataatttt ttaattttta tagttattat tttactaact tgctaattta tgattatttt
    43681 gttctttaat atgttttgct tttttaaaga ataaaagacc aagaattatt gctacaataa
    43741 cacctattcc attagatata ttaactggta gtctaaatcc ttcttttgct tgcattatat
    43801 aactaaatgt tactacagtc ataaaaagtg ctggtaatgt agttatataa tggtttttat
    43861 ttgctttgac taaatatgca gaaccagtcc acaacattat cattgcaagt gtttgatttg
    43921 cccaagagaa atatctccaa attatattaa aatctataaa tgtaagagca acaccaactg
    43981 cgaataatgg taaagctatt aaaaatctat ttttgactgc atcttgatta taattcattg
    44041 catctgctat tgtcagtcta gcacttctaa atgctgtatc tccagaagtt ataggacatg
    44101 ccacaactcc aagtatagct aaagctcctc caataggacc cattaatcca acagatactg
    44161 tatttactac tgttgctgct ccaccatcat taaatatcac attaagttga ggtatgccat
    44221 ggaaatatga catggctgct gctgcccaaa ctaaagctat tataccttct gcaaccattg
    44281 acccataaaa tactggtctt gcctcactct ctttctcaac acatctcgcc ataagtggtg
    44341 attgagttgc atgaaaacct gatattgctc cacatgctat tgttataaat aagtatggga
    44401 ataaaggtgt tccatttgga ttcatatttt gtaaatttat atttggtatg ttatacccct
    44461 ttattattaa tcctccagct acacctactg ccataattaa taatgctgct ccaaataaag
    44521 gatatatttt accaatcaat ttatctattg gtaaaacagt agccataata taataaagta
    44581 ttatcactcc aacccatatt tgtgcgttta cacctgtcaa tgtctttaat aatcctgctg
    44641 gacctgttac aaatacaact ccaaccaata ctaaaagaat aacactaaat attctcattg
    44701 ctatttttgc accatttcct agataaaggc ctaccaactc tgatgcagat gtacctttgt
    44761 ttttcattga tagatatcct gaagcaaaat cgtgtactcc accagcaaag attgttccaa
    44821 acacaatcca taaaaatgct gatggtccaa ataatgcccc ttgtatagct ccaaatatcg
    44881 gacctaaccc tgctatattt agaaactgaa ttaaaaagat tctcttccat ttcattggca
    44941 cataatctac tccatcccta caagctatag ctggagtttg atttttgtca ttgattccaa
    45001 aaaccttttc tacaaaagta ccatagacaa aataacctac tataagtact actattgaac
    45061 ctaaaaagct taccataaat tcatcccctt agtttttata taattgcttt ataaattttt
    45121 atgagtttaa gaaaactatt tccagttcaa atagtaatac ttttttatac taatataaat
    45181 attaattaca ttaagtgcat atttaagtac atgaaatgac tttatatatg cattaacagc
    45241 ctaaattctt ttactttgct tctacttaca gttacttcat agtcactatt ttttaatttt
    45301 aatatgtatg tattattaaa ccatggtata atttctttta ctttggttaa gtttacgata
    45361 taagacctat gtgttctaaa aaatgtttta tcatttataa gattttcgac ttctgatatg
    45421 ccttctttta atataaactt ttctttctca gtatatataa atgtctgcct ttcattagct
    45481 tcacagtaat atatatcatc aatatctatt acaactaatt tatcaccttt ccaaaggcta
    45541 attttatgtg ttatttcttc tatctcctga tttactgctt ccttcttata tttgtataaa
    45601 ttactattta cattagatag ttcaatatca ctcatctcac ttttttctaa tttattcagc
    45661 atagaaataa ttctctcttc agaatatggt ttcaatatat aatcaaatac atccaaagaa
    45721 aaagcatcta ctgcataact ttcatatgct gttataaaaa caattttagg tcttgattta
    45781 aactgattta atgtttttgc aagtagcatt ccatcaagat gaggtatatt tatatctaaa
    45841 aaaattacat ctattttatt ttcctgaata aagtctaaca cctctatacc attggtaaat
    45901 tcacttacta cctcgattcc acttttattt tcaataaaat atctcaattc ctttcttgct
    45961 ggaaattcat cttccactat tatagctctc atacttctac tcctttacat aaaatactat
    46021 caaagtccca ttatctattc ttcttatatt aagccctctt ccatacatca gtttaagcct
    46081 taaatgtaca ttataaagcc caatcttatt ttctggcata ttatcttgat atacattatt
    46141 tataatttcc tcacttatac ctataccatt atcctctatt gatattctca cagtattttc
    46201 taatgaatac ggtaactttt ttatggatat tttcactaca ccagctctac cactttctaa
    46261 aataccatgt attattgcat tttccactaa tggttgtata atcaaacttg gaatctttat
    46321 atttacatct tctatatcat aagatacagt tagtaattct ccaaacctag ctttttctat
    46381 ctctacaaaa gatttaactt gttcaatctc tttatttata tcaattaagt tatcactata
    46441 ttcaagatta tatcttagat aagttgataa atttattatt aactctctag ccttatctgg
    46501 actaaatctt ataaatgaag ctattgtgtt tagggaatta aacaaaaaat gcggattaat
    46561 ttgtctttga agtgctttta tttctgcttt atttctcgct tctatatctt ttttatcttt
    46621 ctcaatcccc tctactatag atataacaaa tcctattcca atctgcccaa ctactaaagg
    46681 taaatatatt ccaccgatta tttgaattgc taaagaatgt ggatatgata ttaagtatat
    46741 aagtaatata gtaaaacttt cagaaatcat gcctaccaat attccataca ttactctatg
    46801 ttgttttggt atcctcttat atagaaatcc tgataacaca cctgctagta tacttgataa
    46861 aagacatgga acagatgtta tccccccaat atccataaaa tatctatgaa tccctgaaaa
    46921 aactcctgct gtaataccta ccattggacc aaataaaatg ccacctgata ctatagatat
    46981 tattctagtg tttactattg accccatata atttatacca ctataagttc caaatatggc
    47041 taaaaaagta aaaactaatg ctatacagac caagtcatta aaactatatt cttccttttg
    47101 aaatatctgc ttaaatattt ttaactttgt tattagaaga aacaatacta caataaggct
    47161 tgtcttttct attaatgcga ttaaaattga tgttttcata atcccccttt aaaaaataaa
    47221 acattactta atttaagttt attattctta taataaatta gatacataaa aataaattcc
    47281 ataattattg tatcatatca cctatatata aacataaatt catttaatta tataaattta
    47341 aaaaatattt ttttgatata ttattgacaa ttttcattat aagagttaaa attaactcat
    47401 aaattacata ttgggtataa aatgcaatgt atgttagaag ttgtttcaga aggctatggt
    47461 tttctgattt ttttatgctc agtagtgata tgcaaaaaag acaaagttga catcagttaa
    47521 cttttacctt tattctactt tccccaaagt aagaataatc taaccccttt gagatgagca
    47581 aaagctcatc tttttttatt atcaaaagat gctgtctcaa aacagagata atcctctttt
    47641 tcattgttga aatgattaaa atatatttta tttcatacaa aaaagagtgc ctcataaaca
    47701 aaagttcact ttgagactct ctctttcata tcatatacct ttttaataac tttaaaattt
    47761 atttatcaag taaagatagc taataattag tatcttctct ctataaatcc aactttttta
    47821 taaacttttc taagagtttt tctagcttgt ttttcggctt tttctgctcc catactatat
    47881 attttttcta aataatcttt attattaaga aggtcaacat atttttctct tataggtctt
    47941 aaagcttctg atactacttc agccacatct tctttaaata tgccataacc ctttccttca
    48001 tacatgttta caatctcttc tacactcttt ttacttaaat tagaatatat atcaattaga
    48061 tttttaatac ctggttgttc atcatcgtat tttacaacac ctaaagaatc agtaacactt
    48121 ctttttatct ttctctttat agaatctgaa tcatctgcta atagtataaa tgcattttca
    48181 tttaaatcgg atttactcat ttttttagtt ggctcttgca aactcatcac tcttgctcca
    48241 ccttttgggt agtatccttc tggaactaca aaagtaggtg aaaatctatt attaaatcta
    48301 tttgctaaat cacgagctaa ttctaaatgt tgtttttggt catctccaac tggaactagg
    48361 tcagtttgat acaacaatat gtcagcagcc ataagaactg gatatgtgaa taaacctgca
    48421 tttagatttg cttcactctt ttgtgattta tctttgaatt gagtcattct acttaattca
    48481 cccatataag tcatagtatt taatacccac ataagttcaa catgctcttt aacatgtgat
    48541 tgtataaata tagtattttt ttctgggtct aatccacaag ctatatattg agcaagtaat
    48601 tctatagtat tggctcttaa aactttaggg tcttgaggta ctgttattgc atgcaaatca
    48661 actatactat aatagcaatc ataattgtct tgaagttcag tccagttttt tatagctcct
    48721 aaataatttc ctaaagtcat tttgcctgat ggctgtgctc cactaaatat aacttttttt
    48781 tcactcattt ttttgtacct ccttatatat ttatattgat tttaacatat ttaaaactat
    48841 gtctttagag ttattggcag catcatgtac aaatacatca taagtaacat cagcacttcc
    48901 atctgcctta tcagacattg ctcttattat tacgaatgga gtattattta aatagcatac
    48961 atgagctata gctccacctt ccatttctcc acaatatcca ccaaaatcat ttactaattc
    49021 ttcttttaat tctttagaat ttataaattt atctcctgta actactcttc cttttaatac
    49081 tttatgagtc tttacttctt ccacagaaga tttgtaagca gcatctataa gtctttcatc
    49141 tgctttaaat acagaagtct tcattcttgg tataactccc ttagggtctc caaatgctgt
    49201 agtatctaca tcatactgta tagcatcagt tgatattact atatcattaa catcaagttt
    49261 ttcatttaaa gctcctgcaa cacctgtatt aacaatagca tcaaccttaa attcgcttat
    49321 tagtatctgg gcacaaagag cagagttaac cttacctatg ccacacttta ctaacactac
    49381 attcttacct tccaaaattc ccttataaaa ttctaagcta gcttttttta tagtctctct
    49441 aatatccatt aaatcaacta aaatactaac ttcttcatcc attgcaccta taattcctat
    49501 tacgttcatt tttcctccta aattttctat attaaaaaat ccgtcctaaa tcaataggac
    49561 ggatatattt tccgtggtac cacctaaatt tatatacact caaaattgaa tatatatatc
    49621 ttaatatatg ctataacgtg catacacgat atcaaatact ctgtaatctt aaattacatt
    49681 tcattttact cctcaaagac ccattcaata aatacttttt attaagttct cagcatcctt
    49741 aattctctgt gcaaaaatat atttatttac tatttcttat ctcaggattt aatttattaa
    49801 tttctttatt ttataatatt ccttacacta taaattgtca actatatatt ataatatcca
    49861 aaagaaattt ttaaaataca ttttatttag ctgttttctt ttcatatcta ttccataacc
    49921 atagaccaga taatataact agaagacctc caccaatcat ctctatctca tatataacat
    49981 tttcagcaaa tgtaggcata actggtgctg cagataataa tatacccact acagttacaa
    50041 ctaaaaccat ttttgctaaa cctaggcaag tacttgttga ttttgccata gtataaggtc
    50101 taatttcatc tggtctctct tttcttagtt taatataaga agcatataac aatacatatg
    50161 ggaataatgc agttaatgct gtcatagtta caagaacatt gtatatagca tcaacagaag
    50221 gcattaatgt agtcaccaat agtattatag taactattat tgcttgaagt ataactgctt
    50281 tagaaggtat cttgtgttca tttacctcta ctaaactatc tggaaatatt ccttttttaa
    50341 cactaccaaa taacattttt attggtgatg ctatgtaaag aactattgct cctaatactg
    50401 aaaaagctat accaaaagct attaattgaa ccaaccaaga accaattcct aaagacgcac
    50461 aaacagcaga aagtgcatct aatacacctt tagaagcagt aatttggtct ggtggtatta
    50521 tcattgttat tgcaattgaa cctaatacat ataatgaagc tactattcca gctgatatta
    50581 atattgcctt agggaagttc ttttcaggct tatctatttc tgttatgaag ttagcagcag
    50641 tctctgctcc tgctaaacca aacattatag ctgatatagc aacaaatgca tccatattaa
    50701 gttttggagt cattgaagct attgtgtatg tagaagctat atcatgtttt ttcaatacaa
    50761 atactgctac aaatgaaaat attataagta tagcacttgg tattgttgaa cctaatgcac
    50821 ctgtattagt aaatattttt gtaaaactta ttcctttagt tgctataaga gataatgccc
    50881 agaatattat taaagataat ataagtacaa acatcttatt atcagcaagg gctggatttc
    50941 ctattgtata agaaacattt actgctaaga aagttaaaaa tgaagaatac caaaatattt
    51001 tagctgtcca gtttaaccaa gaaactaaaa atccatactt ttctccaaag gcttccttaa
    51061 cccaatcgta aagacctcca tcaccttttt gatatgtaga agctaattca gcacaaatta
    51121 aagctcctgg tacaaagtat ataaatgaga ataataacca cataggtatt gcacctaatc
    51181 ctaaaccaaa gcttgatgct gtagatttag ctatccatct tataccatat aaagctgata
    51241 cattcataaa taccaaactc cataggccta tttttttctt ttccatccta atttaatttc
    51301 ccctctctat taattatttt aaatttaatt tcaaaattaa taaaatagat tcattattat
    51361 taaactgata tttttcaaaa tatttgcata ttcaaaaaca gttttaataa taaaccttaa
    51421 atactttgaa atcaaatctt attaaaaatg ataaatttaa aagttttacc actttaattc
    51481 taatgatac
//
LOCUS       DAEORM030000026        48293 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.026, whole genome shotgun sequence.
ACCESSION   DAEORM030000026 DAEORM030000000
VERSION     DAEORM030000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 48293)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48293)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 48293)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48293
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.026"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            184..1020
                     /locus_tag="KRH23_001983"
     CDS             184..1020
                     /locus_tag="KRH23_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HHS5225263.1"
                     /translation="MNIKKIFNNNVVVSSLEDGTEIIVTGAGVGFKKKVGDLIDENLI
                     SKKYFVQDDQRDKYNQILNKTSIEYFKISEEIIEKANEVLNTQVNDSIILALTSHIEF
                     AVQREKQGIKLPNLILNETKQLYREEFEFGLWAIDEIEKRIGIKLPEDEAGYIAIHII
                     NGLENSQKDEGINILEFSKQVIQIIEEVHGFKLDVNSLNYTRLITHLKFFVQRILRKE
                     TYNDSDIEDMYKLVNKNYNKPKVCTEEIAALVLDRFEYKISKEEELYLMIHINKITNS
                     GC"
     gene            1373..2950
                     /locus_tag="KRH23_001984"
     CDS             1373..2950
                     /locus_tag="KRH23_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HHS5225264.1"
                     /translation="MKKNKLGLWNFFQMLGKTFMFPIALLSVSGMMLGLGAGFTDPKM
                     IEMVPFLGNEYVNLVLNFMLTIGLFAFNNLGALFAMAIPLGLLKKEKEFGAFSGLVGF
                     IAMHIGTNFYLTRADLLVPAEQMSTNGQAMIMGIQTYNTSVLGGIVAGLIVYAIYDKV
                     SNLKIPESLGFYSGPRLVPIVSLIVMSIVGLLIPIVWPPFFNAFQSLGRWISSAGPLG
                     YFSYAVAERVTIPFGLNHLVTSVFRFTPIGGTAVIDGETYFGTLNMFMAYVENNQIIP
                     LDLAGKMEQGKLMIQYGLAGAALAIYRTAKPENRKALKGLLISGVLTVIIGGISEPIE
                     FLFLFISPALFAFHTFMNGLANMVLPYLGVLMGFTGDLIAFISFGVLRGTATGWPIAV
                     LVAVLYFAIYYFVFKWAIIKFNIKTPGREDKEIKVSEGNGSDFKNLSTYKGQQMISAL
                     GGQSNILSLDNCVTRLRLKLQDVSLINEDAIKEAGGIAVVKLDEHTIQVIIGTQVYSL
                     RKQMDKAMEGHLEACND"
     gene            2943..4127
                     /locus_tag="KRH23_001985"
     CDS             2943..4127
                     /locus_tag="KRH23_001985"
                     /EC_number="4.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0047804 - cysteine-S-conjugate beta-lyase
                     activity [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MalY/PatB family protein"
                     /protein_id="HHS5225265.1"
                     /translation="MINFDKKVDRLGTYCTQWDYVEDRFGKKDLLPFTISDMDLEFPF
                     EITEVLQERLNHRVLGYSRWKHDDFRNSVTNWYIKRFNCSVDSNWIYYSPSVMYSISK
                     LIEMLSNEGDGILINTPAYNAFYDVITNNNRNIIKSHLVNRNGFYSIDFNDFEKKCKK
                     SKIFILCNPHNPIGRVWSELELVKMIGICKNNDVKIISDDIHMDIVYDNRMTPILNVA
                     KDYLDSVFICTSASKSFNIPALTGSYVIIPNEGIRNKFENITRYRDFVNSPAILAILA
                     TMVCYDDCEYWLDELLKYLKENLKYTIDYIKDNLEPLKLVMPEGCYFAWIDFSELKIS
                     GEKFQKLLMDIGEVAIMSGSVYGEESEFYLRLNVACSREKLEDGLNRIKKTMDYIAKR
                     NL"
     gene            4145..4744
                     /locus_tag="KRH23_001986"
     CDS             4145..4744
                     /locus_tag="KRH23_001986"
                     /EC_number="5.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="KpsF/GutQ family sugar-phosphate isomerase"
                     /protein_id="HHS5225266.1"
                     /translation="MGYLKTMVDVMTTEMNAIRCLIDEAGIEYESIVSEIANCEGKVI
                     FMGVGKSAHIGKKLAATFASTGTPSFFVHATEAVHGDLGMIESKDITILISNSGNSME
                     VVNCIKYIKAIGSKTIAFTSNRNSVLAKECDYALIYPAKDEADHLNLAPTTSSTITLV
                     LGDSIACALSKSSNFGSSDFYKYHPGGSLGEKLKTANNG"
     gene            4768..5238
                     /locus_tag="KRH23_001987"
     CDS             4768..5238
                     /locus_tag="KRH23_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HHS5225267.1"
                     /translation="MFKMFKKKSIKSPISGKVIELSKIQDGVFSQKIMGEGVAIDSTG
                     DIVYAPINGKIVVVAETKHAFVIELENGMELLIHVGLDTVNLKGEGFEVLVSMGEQVK
                     EGTPMLKINRPLIESKGISLITPVTITNHSEYNMNTCNVGNSVEGGKDTVIEFK"
     gene            5597..6343
                     /locus_tag="KRH23_001988"
     CDS             5597..6343
                     /locus_tag="KRH23_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2087 domain-containing protein"
                     /protein_id="HHS5225268.1"
                     /translation="MKIENLSIDDIKRGYIFNDDLNCYSCIKCTKTYEVGEIYKIGNR
                     FFEASKAIELHMELEHSDYLEQLLNSDSKYNTLTENQKQLFQLFISDLPDKEIAKQVG
                     VSTSTIRHQKFIFREKAKQAKFYLALYESVFEDKSNKSSTIIPIHEHARMVDERYVVT
                     EEERKHILDTSFESMNPLKLKVFSSKEKKKVVILSKILEQFERGKKYSEKEVNQILES
                     IYDDFATIRRYLIEYGFMSRNKECTKYWLT"
     gene            6404..7078
                     /locus_tag="KRH23_001989"
     CDS             6404..7078
                     /locus_tag="KRH23_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HHS5225269.1"
                     /translation="MNDELKSILYNKGVDIVRFVDISEFPINQTQGFSKAILFCIGLS
                     KKFITDIYNNLPTDSDEFLEKEEKVEELADWISKYIQNKGYRAYSQSEKNNLEHGYFE
                     KAYINPEMQSGISPLPHKTIANISGIGFMGKNNLFVTEEYGCAFSMCTVLTDAPISVE
                     RYPLIDSKCMDCNVCVENCPAKAIHGNEWTLPGKRESIIDVSKCFCVLRCMMSCPWSL
                     RYANQK"
     gene            7447..8793
                     /locus_tag="KRH23_001990"
     CDS             7447..8793
                     /locus_tag="KRH23_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 55 protein"
                     /protein_id="HHS5225270.1"
                     /translation="MEIETKTPDWINVLELNSKIDITGKYDVSNMIQNIVSDKSLEGS
                     IIYFPKGNYLFEKGIKISQQITLQGDSYYGGDNQVSNLDKKQSIIGTTNFITRGVSNM
                     SIIALTGTSQCIKNINFYYDSHDIEKIPPKNVSAITEYGETQGLSHFEHLFISGFSGI
                     GIEIPYYSTGNDITVSSCGLGMRLGEKSMLSSSKIYECKNGMEITTGVSLNNVRIEEI
                     KEIGINNKGFGFNLIMNLMVDQCGYCGFMFEKMCYSQITARITRCGQYYKSVDYNAYE
                     NMEDRKEEAYSIFYGDILENCNIVLMNSNIDTLENDSLDEHKIYVIKANETNNVMLTC
                     YAEADNFIQCAKGNLLLENGVNTYKFYNGEICSVGGVQISDIDEKDLIKIIENTLYID
                     DKGKYLMVPRLKKNTVIYSVLDSTEEINKLHGGIWEQIDVKVLAGESMYYYKKIKD"
     gene            8820..10220
                     /locus_tag="KRH23_001991"
     CDS             8820..10220
                     /locus_tag="KRH23_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 28-related protein"
                     /protein_id="HHS5225271.1"
                     /translation="MEESIIIKDISGWINVLDYGICNDETKDVSFKLQEIMDAVPEDS
                     IIYFPKGKYLFESGVKIKKRLTLCGDSYILANVPKNTAGVTQFTFKGKKNPKSENIAI
                     ITAKSVRHCIKSICFYSDSCDRDMKSNHEPPTDGKPRFHHNVIINYRNISAIVCEDKQ
                     GESGHYENLSFSGFSGIALDMPNNSTANDITIFTSGLGISTGENSTIANSKIWGCVDG
                     MIISTGTFINGMRVEEIKKVGIKNIGRGLNFITNITIDQCGYCGVWFDSISNVQISGN
                     ITRCGQYYYDVSYDNYLMLDNRVKEAYSLFYGNLLESSNIVLSNTNEDNWEDFKEDKH
                     KVYLIEALKTKNVLLTCNIDATDWIVKSEKGNLTYNNMRQTVIFYDGKLSSINGIGIS
                     DEDYGDKVKIKKGNIYINSNDKDIKMHKPEVGDIISTIIKDKSILSAHYGGTWEKIGE
                     KIEFGITVHYYKLIEK"
     gene            10430..11857
                     /locus_tag="KRH23_001992"
     CDS             10430..11857
                     /locus_tag="KRH23_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 55 protein"
                     /protein_id="HHS5225272.1"
                     /translation="MEGRTGIKDGRWINVVERGIKNDGSYNVGPALQDIIDEIETDFC
                     VLYFPKGKYLFTSGVKINKEIVLQGDSNSSTGTTQFITRGVENMSIITLTGKKQCIKN
                     INFYSDSCEIQVNKEPPTKGNPKYHYEMIINKNEKNVEMNNVSAILYDNSKNMIKGLG
                     HYENIYISGFSGTGIRIPYYSIVNDITVSSCGLGIDTGIDTIISNSRISKCQNGMRIR
                     TGTSINNVRIEKIQKVGLISSQVKGYEGYGSYKINNITIDQCGYCGFSFDSMKDSYFS
                     GIIRRCGQYYYNTDYDTYLSIKDRVEEAYSLFYGNYFTECNIDLVSDNKDNWDDGLEY
                     KHKVSVFKTLQIPKLTLRCNIDAYDYIVKSVHGGGNLMLKNNFNNYIFIDSSSPEVIN
                     GINFNYQKNGNLLRLNNGKLSYKNGKEETAIFRPNYGLIVASTDSECEQIETSYGGKW
                     EKLGSEVIGKETVYYYKHHEPDKTN"
     gene            12210..13154
                     /locus_tag="KRH23_001993"
     CDS             12210..13154
                     /locus_tag="KRH23_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1848 domain-containing protein"
                     /protein_id="HHS5225273.1"
                     /translation="MIVSVSRRTDIPAFYSKWFFNRLEEGFVYVINPMNPKQVSKIEL
                     NPHTVDCFVFWTKDVTPMLYDLNKLKDYKYYFHYTITSYGKEVETCILDKRKVIDSFK
                     ELSRKIGKERVILRYDPIFLSEKYTVDYHIKAFASLCNQLDGFTEKCIISFIDLYKKT
                     KFNTKALHIKPIEITEIETLSKEISKIAHKHGITLEMCSEEYNLSKFGIGKSKCIDDR
                     LISKIIGCEVEVKKDSTQRDICGCVKSVDIGQYNTCRHYCLYCYANFNYAKVEENCRL
                     YKEGNKLLIDTLRDDAKISIRDMKTIKVDKNKQISIFD"
     gene            13323..14255
                     /locus_tag="KRH23_001994"
     CDS             13323..14255
                     /locus_tag="KRH23_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HHS5225274.1"
                     /translation="MNLLKKYPIPIASLILSIFTLGNLLQSYSESLRNVIGFIGFILY
                     AIYIVKIVLLRKGVKEQLENPLISSTFPTITMATMIFATYIKPLSLELSIMIWSIGIV
                     GHLVLIVLFSKKFLVKFSIKTVFPSWYIVYVGIVVASVTAPAFNQLLIGKIAFWIGFV
                     SYIVLIPVILKRVWIIKEMPEPSLPSIAILAAPGSLLLSGYINSFSDKNNVVLYLLFI
                     LSIVFYIIVLGYLPKLLRLPFYPSFAAFTFPMAISAMGMKLMNGYLTKSGHFISWISY
                     ASKLEEIIATVIILYVLVLFIIYLSKSETTSKAK"
     gene            14360..14827
                     /locus_tag="KRH23_001995"
     CDS             14360..14827
                     /locus_tag="KRH23_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C-GCAxxG-C-C family protein"
                     /protein_id="HHS5225275.1"
                     /translation="MKTKEEYLKEVRNISEEYFRKGEFFCSEAVLQTINDALGQPLSP
                     EITKLASGFPIGLGKAQCLCGAISGGEMALGIVYGRVHGEAMNPKMFEHAKGLHDYIK
                     KEYGATCCRAITKKWDGDNFMSPERKEHCIKITGQVTEWVADKLIEDEKLNIK"
     gene            complement(15071..15943)
                     /locus_tag="KRH23_001996"
     CDS             complement(15071..15943)
                     /locus_tag="KRH23_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GRP family sugar transporter"
                     /protein_id="HHS5225276.1"
                     /translation="MKGNSLMLTIIIALLPVMGWGLMPIVANLKKSSPHEQLLGTSIS
                     AFIFSTIITLVIHPEITIFSFCISMISGIFWSLGQLMQFKAIQIASVSKVMPISNGSQ
                     LTFTTLLAVILFNEWTSSKMLLIGSLSILCIILGILLTNYQTKKSTDKNMLKCVGVVL
                     LSSLFLSLYVVTNQIFLIEGYRIILPQSVGMLITSSIIVKYFSKEIVYRENVLFNLIT
                     GILWSIANLGMFITTNTLGVTISFSISQSCVIVATLGGIIFFKEKKNKKEWLAIFIGI
                     ILIMSGVFMLSIIK"
     gene            16091..18055
                     /locus_tag="KRH23_001997"
     CDS             16091..18055
                     /locus_tag="KRH23_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HHS5225277.1"
                     /translation="MLTDMIQNREIKIIKFLLKEGHTTVKAIADDLDVSEKTVSKSLK
                     EVEAVLKKIGLSLIRKPKIGVYIDGDLKKILPYLDNKGSQIPTTREERVIYIYSVLLK
                     SNDYITIQQLSDELYISRGTIERDLAEVEKLLKNEGISIYKKPSKGIKLNISERDKRQ
                     LTAKFIHKFWSRNWYIKQEQESFYQAFEKIQADVNGIFSEDDLSIIIDILRNFSRERK
                     FEFSDYEFQSLVIHLAIAVERIRKGEYIEESLYIGNIENNQMSNTNYLAKQLEEKFSI
                     LLPKSEIGYINLHLVASDQHRDTNELKNTSTNPCETSTNNISNLREIIKNTLYETAYD
                     KDLIDGLTSHVHSSINRLKYGLSIKNPYVNTIKQNFSLSFEQALDLKKVIEFIYDIRI
                     NDDECAYIALHFEAFRERMKELPQNIRVILVCSTGLGSSRLLSARIKKYFPMIKIEKV
                     LSVQELVSSKIDADLVISTIYLELETIPTIVVSPILNESDIRTLERNIQNVSCCTSKK
                     YKSFRNLIFEENILLNIETSNYEDAINHITDNLIKKGFAKEGIAKSAIERENLSYTSF
                     QSIATPHANPSYIKKSNISVATLKNPITWGNEKVEVIFFISLENDKNLELDEIYEVFY
                     DFIDNKKNINDILSATSTKEVYDLLVEESI"
     gene            18055..18516
                     /locus_tag="KRH23_001998"
     CDS             18055..18516
                     /locus_tag="KRH23_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HHS5225278.1"
                     /translation="MKISDVLKKEQIVFNLDTNTKEETIKKLSSIFVENGIVDNEEEY
                     VKSVLEREEHSTTGIGNGIAIPHGKSNAVKKSSIIFAKTKHKIEWDALDEKPVDSIFL
                     LAISNIDKDSNHLVLLSKLATKLMDDDNVDALKLANSEQEIINIFSEEGEM"
     gene            18519..18839
                     /locus_tag="KRH23_001999"
     CDS             18519..18839
                     /locus_tag="KRH23_001999"
                     /EC_number="2.7.1.202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_function: GO:0022877 -
                     protein-N(PI)-phosphohistidine-fructose phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_function: GO:0090563 - protein-phosphocysteine-sugar
                     phosphotransferase activity [Evidence IEA];
                     GO_function: GO:0090582 -
                     protein-phosphocysteine-D-fructose-phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HHS5225279.1"
                     /translation="MKRKIIAVTACATGVAHTYMAAQALKKASKKMGHLIKVETQGAT
                     GIDNELTTKDAQIAEVVIFAVDTKVRNAERFEGKEILEVPVNAPIKDAEKVINDALKL
                     IDTK"
     gene            18855..19955
                     /locus_tag="KRH23_002000"
     CDS             18855..19955
                     /locus_tag="KRH23_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HHS5225280.1"
                     /translation="MLKKIVSELKKHVLTGISYMIPLVIAGAMIMAISRVGGSFYNIP
                     DIWDAKYAESASSIVRLLHDLDGFGGTALGLMFPVIAAFIGFSIADKLAIVPGLVGGM
                     IAKDIGAGFLGALAVGLIAGYTCLFIKNHVKLPKSAASIVPIFIVPVFGTLITVVLIN
                     YVIGIPFATLNTGLENWLNGLSGTNQILMAAIIGAMMAVDLGGPVNKAALTTSLALLT
                     SGIYAPNTAAMVGIVIPPLGLGLATILAKQKYNKQLREAGKSSLIMGLIGVSEGAIPF
                     AVESPLKVIPSCVIGTAIASAMAVGLGSVNATPISGFYGWFTVENWPMYVLSIAVGTV
                     IVAGLVIVLRGNPVIEDDEFEDDDFDEAEWES"
     gene            20075..22675
                     /locus_tag="KRH23_002001"
     CDS             20075..22675
                     /locus_tag="KRH23_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HHS5225281.1"
                     /translation="MIKAHIVNHTHWDREWYFTSGDALVLSEQLFTDVIDELERNPDV
                     SFVLDGQLSILDDYVQLHKEKIEIIKKLIKEDRLHIGPWFTQTDAFFARGESILRNLM
                     IGIFESKKYGKYMKIGYLPDTFGFNAQMPILLKHVGLDNIFFWRGIHLGKQVQSPYFK
                     WKSLNGESYIYAVNMPHGYGTGMLLEPSLKYVNGRLDPAIDFIKSYTDVDEVLIPSGN
                     DQLNIIGDFKNKIKAINDIGKYSYITSSYQEFLKYIKSIESLESYRGEFREPVLARIH
                     KSIGSSRMDIKLACDKLENKLIKRIEPLLVIAKKSKIEISNQLLINTWKKLLEGQAHD
                     SLAGCVTDTVTDDILHRIREANEICDSIENTIVKKISEGLKLSKNDILVFNTEAKRFN
                     GYKEIQVVSDSKNIYFKDNLDATIIEETYVKSRENVLEETPAGNIFIEEPGYYILKVR
                     INIQLPALGYKVVSFESSDKEMVSLDKSNDTFISNDNYKIIYEDGSLNLQLKDGTYIS
                     NFLTLKDSGNAGDTYDFSPLKNDEDIKLSFDKVYTEKALGYEKMVVKGTTLLPLTLED
                     RKNKYLNGKLNVKVSIVLSKENPLMDVKLCVDNTIYNHRLRVHIKTDIKDNKNIASLP
                     FGYITRKNGVLDNWEDIYSEMPIDLEPLESNITLTNQNRSCTVFTRGIKEYQHIEDEI
                     ALTLLATTDELGKPDLLYRPGRASGDTTKKGHIRIKTDKAQMLKELEFSFAIYMDSKS
                     FDELEIANLTHNYLRECVNYQLQDYNFFLYRIDNKIQKSIVNKTVSRELEIISLPKNY
                     LISACYPSYYSKDKFIIRVENPSSNRMILDEQIFKNRNGKIVNAIEDVEEEQVYEIAP
                     FDVISILLDL"
     gene            23144..23479
                     /locus_tag="KRH23_002002"
     CDS             23144..23479
                     /locus_tag="KRH23_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HHS5225282.1"
                     /translation="MYNIDDMIYNCPVEALSNILGKKWVAIIIWKIQEDKKRFGELQR
                     AIPDCSKKMLVQQLDFLIEQGIIVNQKKLVNNVVESTYFLSESGLRLLPVMEKMIMWS
                     NKNLNCDKY"
     gene            23616..24893
                     /locus_tag="KRH23_002003"
     CDS             23616..24893
                     /locus_tag="KRH23_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015036 - disulfide oxidoreductase
                     activity [Evidence IEA];
                     GO_process: GO:0017004 - cytochrome complex assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c biogenesis protein/redoxin"
                     /protein_id="HHS5225283.1"
                     /translation="MQNVNLFLVFIEGIVSFFSPCILPILPIYLSILSNSSVENLKEG
                     KTSFIGSSLFKNTIFFALGISTTFFILGSSVKVLSMFFNENKDLIMFIGGIIIIIMGL
                     FYMGIIKSSILNREKRFNVKFKEMKAITAFILGFTFSFGWTPCIGPILASVLVMVSSS
                     SNHLSANLLIAVYTIGFILPFIITAMFYSKLFKTIDKIKSNMEIIKKIGGIILIVSGI
                     LMMVNGFGSISKHFNTSQNSKIESKQEENKRENSTDKEENSDGNDSQKDSNNDNNDKG
                     SNDEDRIKSIDFTLTDQYGKTHKLSDYEGKVVFLNFWATWCPPCKEEMPYIEQLYKDY
                     NKNNDDVVILGVASPNLGREGSREHVVNFLKDQGYTFPVVLDEDGALAYQYGINAFPT
                     TFIIDKEGYVTQYIPGAMDKATMASFIENQRNK"
     gene            25014..26402
                     /locus_tag="KRH23_002004"
     CDS             25014..26402
                     /locus_tag="KRH23_002004"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase family protein"
                     /protein_id="HHS5225284.1"
                     /translation="MKKTFDAIIIGFGKGGKTLAGDLANRGLKVALIEKSNKMYGGTC
                     VNVACIPTKSLENSANSVKTKNINSWDEVQAEYEKAIDKKETLITKLREANYNKLNSN
                     ENVTIFTGMGTFIDEKTVQVKTENEIYELVADNIFINTGSRPFIPNIKGIENKNIVYD
                     SESLMNLRVLPKKMTIIGAGFIGLEFAGIYSSFGAEVTILNSNNGILPNEDVEDSEEI
                     IKLLAKRNVKIVNNANIKEIKEVSELAIVEYEVDGKSKELTSNMILVATGRKANTEGL
                     GLENAGIELNERGFIKVSETLKTNKEHIWAIGDINGGPQFTYISLDDYRIVINQLFGD
                     KTRTTNDRKNIPNSIFISPAFSRVGLNVKQAKEKGYEVLVAKMPVEAIPRAKQIGKAD
                     GFIKIVIDKKSNKILGASMICENSSEIIHLIQLAVDLEVEYTYLRDRVYAHPTMTEAL
                     NDILSPNMIKEV"
     gene            26848..27486
                     /locus_tag="KRH23_002005"
     CDS             26848..27486
                     /locus_tag="KRH23_002005"
                     /inference="COORDINATES: protein motif:HMM:NF037435.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF434 domain-containing protein"
                     /protein_id="HHS5225285.1"
                     /translation="MKAKEEIEWLLNRDYKIDPVVTFVGDRYQFSIRQRDALKRAVCT
                     DEKNIIRQSKRLSLDKIKEDTVNIDGFNLIISIEVGLSGGTLVIGSDGNIRDLAGLRG
                     TYKIIDKTEEALNLIGKFFNKYNAQNLKFYLDAPVSNSGNLKYRILEHAKTWGIETEV
                     ELVKNADVVLEKLDRVVSSDAVIVDKCISYFNVARGIIEEYIKECNIINLNK"
     gene            27604..28473
                     /locus_tag="KRH23_002006"
     CDS             27604..28473
                     /locus_tag="KRH23_002006"
                     /EC_number="2.3.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0071972 - peptidoglycan L,D-transpeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0018104 - peptidoglycan-protein
                     cross-linking [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase family protein"
                     /protein_id="HHS5225286.1"
                     /translation="MRGWICVKLTKLNIKKYRAPIYKYALANVNLRSAKSTNSSIITV
                     IPQGAKMEVLDEEDDWIKVMYNSQEGYVYKDLVSVSEYAWSNLNLREDKSTTSNIITV
                     IPEKSRVEVLQVDGDWSKVVYDDKIGYVFNYFLSIDGNKPNELDYKYFYTDMIKFVNE
                     NNIKSTSDYLIVTDLRNKYTYIFKKDNGGWGQLYKWQCTIGKPETPTITGIFYISGRK
                     PSFGTDEYSVKYATRIKGGYYYHSVLYDSTGSYIIDGRLGEALSHGCIRLSTENAKWI
                     YDNIPDTTTVIIH"
     gene            complement(28628..29773)
                     /locus_tag="KRH23_002007"
     CDS             complement(28628..29773)
                     /locus_tag="KRH23_002007"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_function: GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HHS5225287.1"
                     /translation="MSIYYVPPINLLGKGCLNEAKDSIKSLGTKKAFIVSDKFLVSNG
                     TVKKVTDILSQIDIDFVVYDEVKQNPTVTNVNKGLKILKSENCDFVITIGGGSPQDCG
                     KAISILATNGGDIRDYEGINKTSKKCLPIIAITTTAGTSAEVTINYVITDEDRHVKMI
                     MVDTNSLATMTVNDPELMISKPSNLTAATGMDALTHAIEAVVANGAYDVTDSTALYAI
                     KQIFKYLPRAVKNGNDIEAREQMCYACFLNGIAFSNAGLGNVHAMAHQLGGLYDLPHG
                     VCNAMLLPIVEEENAKSAPAKFRPIAEVIGMDVNNKSDKECVDFVIDKIKALSEEVGI
                     PKSLKDVGVDNPNFELLAENSMKDACAGANPVFFDKDKIIELFMKIS"
     gene            complement(30106..30882)
                     /locus_tag="KRH23_002008"
     CDS             complement(30106..30882)
                     /locus_tag="KRH23_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HHS5225288.1"
                     /translation="MTSDNHRPTARILDILEALAESENGYTLTEIADVINAPKSSIFP
                     IVHTLNARKYITIDKNTSKYSIGIRSYTLGSSFFEKRTIFNYIIDEMTNIVNSCSETC
                     QLGILDNNEVLYIGKVDSPEPIRLISYVGKKIPANCTGLGKALLCDFDKEKLISLYPD
                     GLKGFTEKSITDFDVLYDQLLEVQRTQIASECEESMEHLKCLAVPIRKNGCIRAAVSV
                     TLPLFRANDEKIELIKKLLLNAQKNIQSMMEERNEDIVIN"
     gene            31464..32438
                     /locus_tag="KRH23_002009"
     CDS             31464..32438
                     /locus_tag="KRH23_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-keto-3-deoxygluconate permease"
                     /protein_id="HHS5225289.1"
                     /translation="MIMDFIKKIPAGMMIVPMFIAAFINTFCPDIVQIGSFTTAVFSS
                     VGSATIIGVQLVCLGTQLQFREMPKVLKRGGILLGSKFAIGALIGILIGKLFGMDGVL
                     GLTTLAVISAVTNSNGSIYLSLMTSYGDETDCATMSLLTLNDGPFFTLIALGTSGLAN
                     VPLLSLLAAIVPILVGMIIGNFDKKMKEFLEPGCNLLVPFVGFALGSSINLASILKGG
                     LSGVLLGLISVFVGGIFIVFCDKFIGKRPGYAGWAVATTAGNAIAVPAAVALVDPSWQ
                     PYVATATTQVAAAVVVTAILVPLITSWWAKKYGCPKFPKQNEDGTITA"
     gene            32536..32841
                     /locus_tag="KRH23_002010"
     CDS             32536..32841
                     /locus_tag="KRH23_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HHS5225290.1"
                     /translation="MINAVIIDEKDNVAVAIEAIAKGSEISFKLKDKTVKTITALDDI
                     TIYHKLAIKDMAKGDKVTKYGEHIGEANQEIKSGQHVHIHNVRSVREDLDKQVMTNI"
     gene            32996..34156
                     /locus_tag="KRH23_002011"
     CDS             32996..34156
                     /locus_tag="KRH23_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HHS5225291.1"
                     /translation="MKFYGYKRPDGRVGIRNHILILPTSVCASDTTRIIASQVQGAVT
                     FNNQNGCSQVHSDQQLTMDVMAGYAANPNVYGVIVVSLGCENCQNDLVVDAIKERTNK
                     PIKTLVIQEEHGTLKTIEKAVRYAREMAQEASLLRKEEFPISELILGTECGGSDPTSG
                     LAANPLIGELSDKLVDLGATSILSETTEFIGAEHILARRAVNEEVKEKILHIVHRYEN
                     SLKLVGEEVREGNPSPGNIAGGLTSLEEKSLGCIHKGGHRQISEVYDYAKQIDKKGLV
                     IMDTPGNDASSVAGMVAGGAQIVVFSTGRGTPSGNPIAPVIKITGNKITFANMEDNMD
                     FDASPVIYGPQTMEELTDDLLNMVVDVANGKQSKAESLGYTEMAIARVCNYV"
     gene            34206..35108
                     /locus_tag="KRH23_002012"
     CDS             34206..35108
                     /locus_tag="KRH23_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fumarylacetoacetate hydrolase family protein"
                     /protein_id="HHS5225292.1"
                     /translation="MKFLSFTEGENECKRTGVFSKDELFIIDVNSLNLSRNFKDLNEL
                     IQNVSSEDIIKLKTIINESTFYNYDVFKRERCTVHVPIEKPIHDILCVGVNYKDHLEE
                     TQTHFDDSFEEPQKTVYFTKRVTKAIGPEDEIDGHFEINNQLDYEVELGVVIGKTGVN
                     IRKEEVEDYIFGYTVINDISARKLQKEHVQWFRGKGLDTFTSLGPCILHKSAVPFPIK
                     LKVCSRVNGEERQSSNTGLFISDVSDIVSELSKGMTLEAGDIIATGTPSGVGMGFSPP
                     RYMSSGDVVECEIESIGILKNYIK"
     gene            35188..36093
                     /locus_tag="KRH23_002013"
     CDS             35188..36093
                     /locus_tag="KRH23_002013"
                     /EC_number="4.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016829 - lyase activity [Evidence IEA];
                     GO_process: GO:0071704 - obsolete organic substance
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HHS5225293.1"
                     /translation="MKAEFLTPVVTIFDEEGNLDKEGNKKVYDHLIDGGVDGLVIMGS
                     TGEFFNMSMDMQKELIDLVTSHVNKRVKVFIGTSRMCINESIELSNYAHNSGADGVMI
                     ISPYYFSLDDDSIELFYSEIAKNTEAEIYLYNYPDRTGYDLSPELTLRLARKHKNIVG
                     YKDTVTLMGHTRDLINTMKIEFPEFKVYSGYDENFIHNLMSGGAGCIGGLSNLIPEVC
                     SKWAEAYNNRDMEKVIEIQKYINKAMDFYLITNPFIPAMKKAMNIRGLQISDYMTAPF
                     VKPNEKQVCEIKKLMNELNICQLTK"
     gene            36789..37016
                     /locus_tag="KRH23_002014"
     CDS             36789..37016
                     /locus_tag="KRH23_002014"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5225294.1"
                     /translation="MKNVLSVEKIEKYYENKDNITKAIDNNDITRLKFKNLDKFRQNE
                     LGFIFQNFNLLYTLIAYENIALTLTIKGKTI"
     gene            37093..37263
                     /locus_tag="KRH23_002015"
     CDS             37093..37263
                     /locus_tag="KRH23_002015"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5225295.1"
                     /translation="MLTNDAFIASYTHRNLFIKYRKIFIELARRTDSIKESFNRIIEE
                     IAIIRGDDNNVF"
     gene            37253..38098
                     /locus_tag="KRH23_002016"
     CDS             37253..38098
                     /locus_tag="KRH23_002016"
                     /inference="COORDINATES: protein motif:HMM:NF014717.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HHS5225296.1"
                     /translation="MYSKIAIKNVRKSFKDYSIYFLTLTLVICIFYSFNSMESQKALM
                     EISTSKKPDLEMFKNMISYISVFVSAILCTLILYINNLLIKKRNKKLGIYMTLGMGKI
                     EMSKILVFETIIVGIVSLVSGLILGLLVSQGLLILLLKLFEFNMSEYSFVISIPAIIK
                     TIVYFGIIFLLVMIFNIYLISKYKMIDLLIVERKTEDIKFKNPFVYMITFVSCFIFLF
                     TVYNTTNHIIINLIDDKQLNSKSKGVEINEFTYQDWQQFCDIKYYGKKGLISMTLKEY
                     IEKYK"
     gene            38353..39120
                     /locus_tag="KRH23_002017"
     CDS             38353..39120
                     /locus_tag="KRH23_002017"
                     /EC_number="7.6.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHS5225297.1"
                     /translation="MKNILSVEKIEKYYGNKDNITKAIDNISFKVDEGEFVGIMGPSG
                     SGKTTLLNCISTIDNVTIGKIIINNNDITRLKSKNLDKFRQNELGFIFQDFNLLDTLT
                     AYENIALALTIKGEKPSKIDSKIRDVATYLEIEKVIDKYPYQMSGGQKQRVASARAIV
                     TNPSLILADEPTGALDSKSARLLLERFESLNQDLKATILMVTHDAFTASYAHRILFIK
                     DGKIFTELVRGADSRKEFFNRIIEVTTLIGGDDNDVF"
     gene            39110..41104
                     /locus_tag="KRH23_002018"
     CDS             39110..41104
                     /locus_tag="KRH23_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018592478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HHS5225298.1"
                     /translation="MYSKIAIKNVRKSFKDYSIYFLTLTLAICIFYSFNSIESQKALM
                     EMNASTKSHVEMLKNMISYMSVFVSVILCSLILYANNFLVKKRNKELGIYMTLGMEKV
                     KISKILVFETIIVGIVSLVSGLILGLLVSQGLSILLLKLFEFNMSEYNFVISISSIIK
                     TIVYFGIMFLLVMIFNTYIISKYKIIDLLTIGRKTEDIKFKSPFVYTITFILCIISLI
                     IAYSMVLKVGLNPKNPKFIMSIVLGVIGTILFFYSLAGFALYIVKKNKNIYFKGLNIF
                     VVKQINSKINTNFISISIICLMLFLTIGILSTGFGFKSALNAGLKGATPFDASATMIV
                     HEKCKVKNIKESFEKVGIKFNKGDKVAYYDEYINGNKLSDVMQGQYSGRVDFEVAYIK
                     SSQYNEIRKLRGEKSITLSKDEVLITSNATEVVPSIEEYMKNNKIIKIDNKAYNIKNK
                     KVIKDNLRTDFTETNALTVVVNDKLCDSMEISSSIVNINFASDNNEKSQENFDKRLKS
                     KYSSTSFYEVGTVSGGSRNAMYNDNNGMTSTILFVGIYLGIVFLISSMAVLALQQLSE
                     ASDSIDRYVSLKKLGASKNSISKTIFTQTLMYFSIPVGLALVHSVVGIQVANNFISRL
                     NKPDIGASSLMTVGILMLVYAVYFYTTYQGYKNIVIKKLN"
     gene            41181..41852
                     /locus_tag="KRH23_002019"
     CDS             41181..41852
                     /locus_tag="KRH23_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HHS5225299.1"
                     /translation="MEKIIIVEDEEVIRDELKSFLERYGYEVMAPTEFDNIVEFILSE
                     KPNLVLLDINLPIYDGYYICRVLRKESNIPIIIVTSRNTDMDELMSMNLGADDFVTKP
                     YKTQILLARIVALLKRSGLNSNVNNTLIFKGIELNLFNATLRYKDKEIELTKNEFKIL
                     SYLVENQGSIVSRDSFMEYLWHTNWFVDDRTLTVNITRLRKKLDEIGIENLIETRRGL
                     GYIIS"
     gene            41849..42856
                     /locus_tag="KRH23_002020"
     CDS             41849..42856
                     /locus_tag="KRH23_002020"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HHS5225300.1"
                     /translation="MRLREYIGDKVVFLGTNLIIFLIASGIMLYSKINVVLIFMLFCI
                     WFLPLFTYMLIDYLQYKKYFNSIDNILDALDKKYLLPEVIDDVNFVTGEKINDILKVI
                     SRNMHENIKYYNDNQEEYKEYIETWVHEIKTPIASSKLIIENNSNEITKKIDTQLDKV
                     ENFVEQVLYYSKIDNVNKDYIIKKLNLEEVVNEVIKRNYRDFINKNIKLELGEINKTV
                     YSDSKWVEFILNQIVVNSIKYIKSKDGLIKISAKRVENSIVLTIEDNGVGIVERDINK
                     VFEKGFTGENGRVFGKSTGIGLYLCKKLCNKLGLGLILESKVNVGTVIKVSFPIDYNL
                     F"
     gene            43021..43416
                     /gene="tnpA"
                     /locus_tag="KRH23_002021"
     CDS             43021..43416
                     /gene="tnpA"
                     /locus_tag="KRH23_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HHS5225301.1"
                     /translation="MKLDSNNHSVFLLHYHLVMCIKYRRKVIDDSISDRLKDIFVDIA
                     PNYGVVLIEWNHYVDHVHLLFKAKPNTEISKLLNAYKSASSRRIKNEFPSIRKYLWKE
                     YFWSKSYCLVTTGGATLEDLEQYIENQEE"
     gene            44010..45140
                     /locus_tag="KRH23_002022"
     CDS             44010..45140
                     /locus_tag="KRH23_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HHS5225302.1"
                     /translation="MKFKSNVLKQFFLIAMVIFMVGGLIGCSKSDKENKQASTGKKLE
                     LKYASGFSVEDLEDGIKKVTDGDNRELILIPKKIKIPEKYKNANIVRTPVDNVLIAST
                     TQACSLRTIDELDSIKAVTTEEQYWTIKEIKDLMKDGKIHYVGSNLAPDYEKIVDLNP
                     DLTIVSSGLSEADTKFIDKLKELGLNYVVDNEYKEQNPFGRMEWTSLIAAFYDKEDMA
                     TSELNKTVQKVEEVSKKIKNKAKPKVVWASVYEGSAYIAPKDSYVDNMIKMAGGINAC
                     ASIDSNEGRVSIEQLHEVAKDADIFVYSSSSDYAPNLDSIKSSAPVLADLDVVKNGNL
                     WVFAPDYYQSVDKTDELIVDLVEMFHPGTTGEKIKHYINYDK"
     gene            45212..46237
                     /locus_tag="KRH23_002023"
     CDS             45212..46237
                     /locus_tag="KRH23_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FecCD family ABC transporter permease"
                     /protein_id="HHS5225303.1"
                     /translation="MDFINKMRIRNTTIFIVLIISMILTFLVCVAFGSVKIEFKEVID
                     VVLRGMDNTEHYKIIYNIRIPRVLATMVGGACLAVSGILLQIFFKNPIVEPYILGVSS
                     GSTLSVALMILGGYTLGFESVNSMSIFVAAFIGALIVMSIVILFANKVKNITILLIIG
                     IMTGYVCSGITNVLQSFANSDKLKEFTMWSMGSFSGFTWEKVEILIIVGILGLLMTVF
                     IIKPLNAFLLGEEYAKSIGINIRFFRVLIVFISSILAAIVSAFAGPIGFIGLAVPQIS
                     KLILKTSDNRVLIPVVIFLGSIVTALCDLISRVILSPVELPISTITSLLGAPIVVMLL
                     VKRKDRA"
     gene            46240..47436
                     /locus_tag="KRH23_002024"
     CDS             46240..47436
                     /locus_tag="KRH23_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHS5225304.1"
                     /translation="MLKTNNLSVGYNNKVVISNINVEVKNGEILCLLGSNGAGKTTLL
                     RSLSKLISPIKGEIYLNGVNINCISRKALSKKMALVLTNRLLGDLMTVQDIVNIGRYP
                     YTGFFGSLSKKDLIMVDEALESVDALHLKKRYFDELSDGEKQKVLVARALVQEPEIII
                     LDEPTTHLDIKHRLELINILKKLSKEKSISVILSLHEIDIALKSCDKVALIKNNKVIA
                     YGQPEDVVDEDIINSLYELDDKNFNSLLGSVEISNKSKNEVFIIGGGGKATPIYRAFT
                     KKGIGLYSGIIHENDIDYEIGRTMGIKMFTENPFEPISDESFGLAIRNLNDSKIIIDT
                     GFSVGETNKRNIDIIKEALKLDKKVYSFRNRDESKKYYDSLDSKIEHIDKVSQIINSA
                     DINNLL"
     gene            complement(47564..>48293)
                     /locus_tag="KRH23_002025"
     CDS             complement(47564..>48293)
                     /locus_tag="KRH23_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HHS5225305.1"
                     /translation="LMKTISKQELEKTLEKHYLWLKNNNAGEKADLKEFRLENMDLRG
                     YCLSNIDFSWSDLINLNLEKADLENSIFNNSYLSDCSLKNSILKNADLSGASFRFCDL
                     SNSDIRGANLENSNLEYATLNGVISDESTRFFKLYCPETGAFIGYKKCFNFRMVQLLI
                     PSDAKRVSATSNACRCDKAKVLSITSIDGKESFKSARAYADENFIYRVGETIVAEDFN
                     ENRWKESTTGIHFFLTREEAIGYL"
BASE COUNT        19019 a         5016 c         8294 g        15964 t
ORIGIN      
        1 ttcaatgaaa atatgataaa atatgacaaa ttaattgatg acaataaaaa atattttgtt
       61 attgtagtat tatagggtaa attgcaaaat atatacgaaa gtaaaatttt aaatattgac
      121 attaaattaa atatactata ctatgtaagt gtgatgagag aattttttta gaggggattt
      181 atagtgaata taaaaaagat atttaataac aatgtagtag taagctccct agaagatggc
      241 acagaaataa ttgtcactgg tgctggagta ggatttaaga aaaaagtagg cgatttgata
      301 gatgaaaatt tgatttctaa gaaatatttt gttcaagacg atcaaaggga caaatacaat
      361 caaatactta ataagacctc tattgaatac tttaaaattt cagaagaaat tatagaaaag
      421 gctaatgaag ttttaaatac tcaagtgaat gattcaataa tattagcctt aactagtcac
      481 atagaatttg ctgtccaaag agaaaaacaa ggtataaaat taccaaactt aatattgaat
      541 gagacaaaac aactttatag ggaagaattt gaatttggat tatgggcaat tgatgaaatt
      601 gaaaaaagga taggaataaa attgcctgaa gatgaagcag gatatattgc tattcacata
      661 atcaatggtt tggaaaattc tcaaaaagat gaaggtatta atatactaga gttttcaaaa
      721 caagttattc agataattga agaagtacat ggatttaaat tggatgtaaa ttcattaaat
      781 tatactagac ttataactca cttaaagttt tttgttcaaa ggattctccg aaaagaaact
      841 tacaatgata gtgatattga agatatgtat aagttagtga ataaaaatta caataaacct
      901 aaagtgtgta ctgaagaaat tgcagcattg gtattagaca gatttgaata taagattagt
      961 aaagaagaag aattatattt aatgattcac ataaataaaa taacaaacag tggttgttag
     1021 gattgtaact gataaagcag gcaaaaccta agtcattgag cttaactatt agattaagtt
     1081 ttttgattta ggttttttta ttagatacaa tcaaaataca gacagtgact tttaggattg
     1141 taactggtta agcaggcaaa acctaaatca ttgaatttaa ctattaggtt aagttttttg
     1201 atttaggttt ttttattaga tacaatcaaa tacagacagt gacttttagg attgtaactg
     1261 gttgagcagg caaaacctaa atcattaaac ttaattatta aattaagttt tttgatttag
     1321 gtttttctat aaatttgatt atgtttttag ataaaaatag gaggggaaaa ttatgaaaaa
     1381 aaataagtta ggtttatgga acttcttcca aatgttagga aaaacgttta tgttcccaat
     1441 agcactactt agtgtttctg ggatgatgct aggacttggg gcaggtttta cagaccctaa
     1501 gatgattgaa atggttccat ttttagggaa tgaatatgtt aacttagttt taaacttcat
     1561 gttaacaata ggattatttg catttaacaa cttgggagca ttatttgcaa tggcaattcc
     1621 actaggatta ttaaaaaaag aaaaagagtt tggtgctttt tcaggattag taggatttat
     1681 agcaatgcac ataggtacaa atttttattt aacaagagct gatttgttag taccagcaga
     1741 acagatgtca actaatggtc aagctatgat tatgggtata caaacatata atacaagtgt
     1801 tttaggtggt attgtagcag gattaattgt ttatgcaata tatgataaag ttagtaattt
     1861 aaagatacca gaatcattag gattctacag tggaccaaga ttagttccaa ttgttagttt
     1921 aatagttatg agtatagttg gattattaat acctattgtt tggccaccat ttttcaatgc
     1981 attccaaagt ttaggaagat ggatttcttc agcaggacca ttaggatatt tttcatatgc
     2041 agtggcagaa agagttacaa ttccatttgg actaaatcat cttgtaacat ccgtattccg
     2101 ttttacacca ataggtggaa ctgctgttat tgatggagaa acgtactttg gtacattgaa
     2161 catgtttatg gcatatgtag aaaataatca gattatacct cttgatttag ctggtaaaat
     2221 ggaacaaggt aaattgatga ttcaatatgg attagctggt gctgcattgg ctatctaccg
     2281 tacagcaaaa ccagaaaata gaaaggcact taaaggactt ttaatatcag gagtgttgac
     2341 agttattata ggtggtataa gtgaaccaat agagtttcta ttcttattca tatcaccagc
     2401 attatttgct ttccatacat ttatgaatgg tctagcaaac atggtacttc catacttagg
     2461 cgtgttgatg ggattcacag gagatttaat tgcatttata agttttggtg tgttaagagg
     2521 aacagctaca ggatggccaa tagcagtatt agtagcagtt ttatattttg caatatacta
     2581 ttttgtattt aagtgggcaa ttattaagtt taatataaag accccaggac gtgaggataa
     2641 agaaataaaa gtatctgaag gaaatggttc agatttcaaa aatttgtcta catataaagg
     2701 acaacaaatg atatctgctt taggtggtca atctaatata ttatcactag ataattgtgt
     2761 aactagatta cgtttaaaat tacaagatgt atcattaata aatgaggatg caattaaaga
     2821 ggctggtggt atagcagttg ttaaattgga tgagcataca atacaagtaa ttataggaac
     2881 tcaagtgtat tctttaagaa agcagatgga taaagctatg gaaggtcatt tggaggcatg
     2941 taatgattaa ttttgataaa aaagtagacc gattgggtac atattgtacc cagtgggact
     3001 atgtagaaga tagatttggt aagaaggatt tgcttccttt tacaatttca gatatggatt
     3061 tagagtttcc atttgaaata acagaggtgt tgcaggaaag gttaaatcat agagttttgg
     3121 gatacagtag atggaaacat gatgatttta gaaattcagt tacgaattgg tatattaaaa
     3181 gatttaattg tagcgttgat agtaactgga tatattatag tccaagtgta atgtattcaa
     3241 ttagcaaact tattgagatg ttaagtaatg aaggagatgg aatccttata aatactcctg
     3301 catacaatgc tttttatgat gtgataacaa ataacaatcg taatattata aagtcacatc
     3361 ttgtaaatag gaatggattc tattcaattg attttaatga ttttgagaaa aagtgtaaaa
     3421 aatctaagat atttatttta tgtaatcctc acaatccaat tggtagagta tggagtgagt
     3481 tagaacttgt taagatgata ggcatttgta agaataatga tgtcaagata atatcagatg
     3541 atatacacat ggatattgta tatgacaata gaatgacacc tatcttaaat gttgcaaagg
     3601 actatttaga ttctgtattc atttgtacat cagcgtctaa atctttcaat ataccagcat
     3661 tgactgggtc atatgtgatt ataccaaatg aaggtattag aaataaattt gaaaatatca
     3721 ctagataccg tgattttgta aattcgccag caattctagc aatattagcc acaatggtct
     3781 gttatgatga ctgcgaatat tggttagatg aactattaaa ataccttaaa gagaatctta
     3841 aatatacgat tgattatata aaagataatt tagaaccatt gaaattggtc atgccagaag
     3901 gctgttactt tgcttggata gatttttccg aacttaaaat aagtggtgag aaattccaaa
     3961 aattattgat ggatattgga gaagttgcta ttatgtcggg gtctgtatat ggtgaagaaa
     4021 gtgagtttta tttaaggtta aatgtggcat gttcaagaga aaaacttgaa gatggtttaa
     4081 ataggattaa aaaaactatg gattatattg caaaaagaaa tttatagtag gaagggagat
     4141 agttatggga tatttaaaaa caatggttga tgttatgact actgaaatga atgccataag
     4201 atgtttaata gatgaggcag gaatagaata tgaaagtata gttagtgaaa ttgcaaattg
     4261 tgaaggcaaa gtaattttta tgggtgtagg aaaatctgca catataggta agaaattggc
     4321 agctacattt gctagtactg gtacacctag cttttttgta catgcaacag aggcagtgca
     4381 tggagattta ggaatgattg aaagtaagga tattacaatt ttaatatcaa atagtggaaa
     4441 ttctatggaa gtggtaaact gtataaaata tattaaagca ataggttcta agacaattgc
     4501 atttacttca aacagaaatt cagtactggc aaaagagtgt gattatgctt taatatatcc
     4561 tgcaaaggat gaagcagacc atttaaatct agcaccaaca acatcatcta caattacttt
     4621 ggttttagga gattctattg catgtgcatt atctaagagt agtaattttg gttcttcaga
     4681 tttttataag taccatccag gaggaagttt aggtgagaag ttaaaaacag ctaacaatgg
     4741 ataaaagcaa aaaggagagt agtttttatg ttcaaaatgt ttaaaaaaaa atcaataaaa
     4801 tcacccatat caggaaaagt aatagagtta tctaaaatac aagatggtgt attttctcaa
     4861 aaaattatgg gagagggtgt agctatagat tctacaggag acattgtata tgctccaatc
     4921 aatggaaaga tagtagtagt agcagagact aaacatgcat ttgtaataga attagaaaat
     4981 gggatggaac ttcttattca tgttggttta gatactgtaa atttaaaagg cgaaggtttt
     5041 gaggtattgg tgagtatggg agaacaagtg aaggaaggaa caccaatgtt gaaaattaac
     5101 cgtcctttga ttgaatcaaa gggtatatca cttattactc cagttacaat aactaatcat
     5161 tcagagtaca atatgaatac atgtaatgta ggcaatagtg ttgaaggtgg gaaagatact
     5221 gtaattgagt ttaaataaag aactaaaata caaggttaat atttataaat acctataaac
     5281 ttatgtttta taagattgat tgtatagatt tgttgtataa aaaagaactc tttaattata
     5341 aattaaggag ttctttttta ttttgtaaat attgtttaga tttatataga aaaacactta
     5401 gtaataaata gaataaataa gtatttatat agctaaaaat ctaaatagtt ttgtttaaat
     5461 atatttttat attttgtaat ttcaaattaa taaataatta gatttgataa acaaaaaata
     5521 aaaatgttga ttacattaat aaactttaat ataatatatt tatgaaaaat gtaaactgtg
     5581 aaatggaggt agtaacatga aaattgaaaa tctttctatt gatgatatta aacgaggcta
     5641 tatatttaat gatgatttaa attgttatag ttgcattaaa tgtacaaaaa catatgaggt
     5701 aggagaaata tataaaatag gtaatagatt ctttgaagct tcaaaagcta ttgaacttca
     5761 tatggaatta gaacatagtg attatttaga gcaattgctt aatagtgatt caaagtacaa
     5821 cacattgact gaaaatcaaa aacaattatt tcaattattt attagtgatt taccagataa
     5881 ggagatagca aaacaggttg gagtatccac atctactata cgccatcaaa aatttatttt
     5941 cagagaaaaa gcaaaacagg ctaagttcta tttagcacta tatgaatctg tatttgaaga
     6001 taaatctaat aaaagtagta ctataatacc aatccatgaa catgctcgaa tggtagatga
     6061 aagatatgta gtaactgaag aagagagaaa acacattttg gatacatcat ttgaaagtat
     6121 gaatccttta aaattaaaag tattttcttc aaaagaaaag aaaaaggtcg taattttatc
     6181 taagattttg gaacaatttg aacgtgggaa gaaatattca gaaaaggaag ttaatcagat
     6241 tttagaatct atatatgatg attttgcaac aattagaaga tatctaattg agtatggttt
     6301 tatgagtaga aataaagaat gtacaaagta ttggttaaca taattaaaat aataaatttt
     6361 actaatgtgt aatgttattt ttatctaggg ggaggagtca aatatgaatg atgaattaaa
     6421 atctatttta tacaataaag gtgtagacat tgttcgcttt gttgatatat ctgaatttcc
     6481 aataaatcaa acacaaggtt tttctaaagc aattttattt tgtatagggt tatcaaaaaa
     6541 atttattaca gatatataca ataacttacc tacagatagt gatgagtttt tggaaaaaga
     6601 ggagaaagta gaagaattag ctgactggat ttcaaaatat attcaaaata aaggatatag
     6661 agcatattct caatcggaga aaaacaatct agaacatgga tattttgaaa aagcctatat
     6721 taatccagaa atgcaatcag ggattagtcc tttaccacat aagacaatag caaatattag
     6781 tggcattgga tttatgggaa aaaataattt gtttgtaaca gaggaatatg gatgtgcttt
     6841 tagcatgtgt acagtactta cagatgctcc aatttctgtt gaaagatatc ctttgattga
     6901 ttcaaaatgt atggattgca atgtttgtgt agagaactgt cctgcaaaag ctatacatgg
     6961 aaatgaatgg actttacctg gaaaaagaga atctattatt gatgtttcaa agtgtttttg
     7021 tgtattgagg tgtatgatga gttgcccatg gtcattaaga tatgcaaatc aaaaataact
     7081 ttactagaga aggtattaaa ttgaatatta taaaattttt aaaatgtaag attatataag
     7141 atttctcaaa ataaaaattt gtatagaaca ctcagaaatg agtgtttttt tattgggatt
     7201 aaattatatt gatacaaagc ttaactattt taatcattat ataaaatttg tattaaaaaa
     7261 ttaagaataa cttggtaata gtgaaaatat aatgagatta taattgattt ataatataac
     7321 tataatgata ttgtaaaaat gaaaattgtc ctctcaaaat tcccaaagag agtaaaagtc
     7381 acttcagtta tagtcaaaaa aatttttctg tgaaaagaat ttagatttga aaaggaggaa
     7441 ttaatcatgg aaattgaaac taaaactcca gattggatta atgtactaga attaaacagt
     7501 aaaatagata ttactgggaa atatgatgta agtaatatga tacaaaatat tgtctctgat
     7561 aagtcactag aaggttccat tatatatttt ccaaaaggta attacttatt tgagaaaggt
     7621 attaaaatta gtcaacaaat aacacttcaa ggagattctt attatggagg agataatcaa
     7681 gtatcaaatt tagataaaaa acaatcaatc ataggaacaa ccaattttat aactcgagga
     7741 gtttctaata tgagtattat tgcattgaca ggaacaagtc aatgtatcaa aaatattaat
     7801 ttttattatg atagtcatga tatagagaaa ataccgccta aaaatgtatc tgctattaca
     7861 gaatatggag aaacacaagg actatctcat tttgaacatc tgtttatttc tggattttca
     7921 gggataggaa ttgaaattcc atactattca actggtaatg atattactgt tagttcatgt
     7981 ggtcttggta tgaggcttgg agagaagtca atgctttcta gtagcaagat ttacgaatgt
     8041 aaaaatggaa tggagattac tactggtgtt agcttaaata atgtgagaat agaagaaata
     8101 aaagaaatag gtattaataa taaaggattt ggttttaacc tgattatgaa tcttatggtc
     8161 gatcaatgtg gatattgtgg atttatgttt gaaaaaatgt gctatagcca gataactgcc
     8221 agaattacta gatgcggtca gtattataaa agtgttgatt ataatgctta tgagaatatg
     8281 gaagatagga aagaagaagc ttattccatt ttttatggag atattttaga aaattgcaat
     8341 attgtattga tgaatagtaa tattgatacc ttggaaaatg attcacttga tgaacataag
     8401 atatatgtaa tcaaggcaaa tgaaacaaac aatgtaatgc taacatgtta tgctgaagca
     8461 gataacttta tacaatgtgc aaaaggtaac ttgctgttag aaaatggtgt aaatacttat
     8521 aaattttata atggtgagat ttgttctgta ggaggtgttc aaatttctga tatagatgaa
     8581 aaagatttaa tcaaaataat cgagaacact ctgtatatag atgataaagg taagtattta
     8641 atggttccta gattaaaaaa gaatactgta atatattcag tactagattc tacagaagaa
     8701 ataaataaat tacatggtgg aatatgggaa cagattgatg taaaagtatt agctggggaa
     8761 tccatgtact attataaaaa gataaaagat taaattatca aactaggagg tagtgattaa
     8821 tggaagagtc tataataatt aaagatataa gtggctggat taatgtactt gattatggaa
     8881 tttgtaatga tgaaacaaaa gatgtaagtt ttaagttgca agagattatg gatgctgtac
     8941 cagaagattc tattatatat tttccaaaag gaaaatactt atttgaaagt ggtgtcaaga
     9001 ttaagaaacg attaacctta tgtggagatt cttatatttt agcgaatgtt cctaaaaata
     9061 ctgctggagt aacacagttt acttttaaag gaaagaaaaa tcctaaaagt gaaaatatag
     9121 caattataac agcaaaaagt gtaagacact gtattaagag tatttgtttc tactcagata
     9181 gttgtgatag agatatgaaa tctaatcatg aacctccaac agatggaaaa cctagatttc
     9241 atcataatgt aattataaat tatagaaata tatcggctat tgtatgtgaa gataaacagg
     9301 gagaatcagg tcattatgaa aatctatctt ttagtggttt ttctggaatt gcacttgata
     9361 tgcctaataa ttctacagca aatgatatta caatttttac atccggactt ggaattagta
     9421 caggggaaaa ttcaacaatt gctaacagta agatttgggg ctgtgttgat ggaatgataa
     9481 tttctactgg aacttttata aatggtatga gggtagaaga aataaaaaaa gttggaatta
     9541 aaaatattgg tagaggttta aattttatta caaatatcac aattgaccaa tgtggatatt
     9601 gtggagtttg gtttgattct atatccaatg ttcagatatc aggaaatatc acaaggtgcg
     9661 gacagtacta ttatgatgta agctatgata attatttaat gttggataat agagttaaag
     9721 aagcatattc tttattctat ggtaatttat tggagtcaag taatatagtt ttgtcaaata
     9781 ccaatgaaga caattgggaa gatttcaaag aggataagca taaggtgtat cttatagaag
     9841 cacttaaaac caagaatgta ctattaacat gtaatataga tgctactgac tggattgtta
     9901 agtcagaaaa aggaaattta acgtacaata atatgcgaca aactgttata ttttacgatg
     9961 gaaaactaag tagtatcaat ggaattggta tatctgatga agattatggg gataaagtca
    10021 agataaaaaa aggaaatata tatataaata gtaatgataa ggatattaag atgcataaac
    10081 cagaggtagg tgacattatc tcaacaatta ttaaagataa aagtattctt tctgctcatt
    10141 atgggggaac atgggagaaa attggtgaaa aaatagagtt tggaataact gtacactatt
    10201 ataaattgat agagaaataa gtaaatacgt agtatttgaa tagatgtatt ttattggaga
    10261 gctaggacta tagttttaat gtaaatggtt tggtaatagc atggattgaa taatataaaa
    10321 ataatataaa aaattaattt gattatgtaa atttctatga agtagtaaaa ctgtgacttt
    10381 agtcatagga ggttcaaact aagtaaaagg gaaaggaata tataatatta tggaaggaag
    10441 aactgggatt aaagatggaa gatggattaa tgtagtagaa agaggtatta aaaatgatgg
    10501 ttcgtacaac gtaggtcctg ctttgcagga tattattgat gaaatagaaa cagatttttg
    10561 tgtcttatat tttccaaaag gtaaatacct atttacaagt ggtgttaaaa ttaataaaga
    10621 aattgtattg caaggtgatt ctaattcatc tacaggtact acacaattta taactcgtgg
    10681 agtagaaaat atgagtatta ttacattgac agggaagaaa caatgtatta aaaatataaa
    10741 tttctattct gatagttgtg agatacaggt aaataaagaa ccaccgacaa aaggtaatcc
    10801 taaatatcat tatgagatga ttattaataa gaatgaaaag aatgttgaga tgaataatgt
    10861 atcagcaatc ctgtatgata acagtaagaa tatgattaaa ggtctaggtc attatgaaaa
    10921 tatttatata agtggttttt cgggtacagg aattaggata ccatattact caattgtaaa
    10981 tgatattaca gtttcatctt gtgggctggg tattgataca ggaatagaca caattatttc
    11041 taatagtaga atatctaagt gtcaaaatgg aatgaggatt agaactggaa ctagtataaa
    11101 taatgtaagg attgaaaaaa tacagaaagt tggtcttata agtagtcaag ttaaggggta
    11161 tgaggggtat ggaagttata aaattaataa tattacgatt gaccaatgtg ggtattgtgg
    11221 cttttcattt gattcaatga aagatagtta tttttctggt attataagaa ggtgtggtca
    11281 gtattattat aatacagatt atgacacata tttaagcatt aaagatagag tagaagaagc
    11341 atattcttta ttttatggaa attattttac agaatgtaat attgatttag ttagtgataa
    11401 taaggataac tgggatgatg gcttagaata taaacataaa gtttctgtat ttaaaaccct
    11461 tcaaatacca aaattaacat tgagatgcaa tatagatgcc tatgattata tcgttaaatc
    11521 ggtacatgga ggaggtaatt taatgttaaa aaataacttt aacaattata tatttattga
    11581 ttcatctagt ccagaagtta ttaatggaat taattttaat tatcaaaaga atggaaactt
    11641 gttaaggtta aataatggta aattaagtta taaaaatgga aaggaagaaa cagctatatt
    11701 cagacctaat tatggtctta ttgtagcatc aacagattca gaatgtgaac aaatagagac
    11761 tagctatgga ggaaaatggg agaagcttgg ttctgaagta attggaaaag aaacggtata
    11821 ttattataaa catcatgaac cagataaaac aaactaaata caataaaatt tgtattatat
    11881 aatgatataa agttttaata tatagtgttt acctttaatg taatattggt atatttgtat
    11941 agtattaaat ttgttaaaaa gtaaaattgt agggtgcttg aaaatagcac cttttttagt
    12001 ttcattataa aattagtttt gaaagtttag gaataatgta tatttatttt taaagaatta
    12061 taatctcatt aaggatattt taaattctag aaatgaatca gtaaatcata ctggaattat
    12121 cttaaatgtt ttgattaaat taagtattta gagctataat tatattaaaa atatattaga
    12181 acataattat attactatgg aggttaaata tgatagtaag tgtgagtaga agaactgata
    12241 tacctgcttt ctatagtaag tggtttttta acagacttga agaaggtttt gtttatgtaa
    12301 ttaatccaat gaatccaaaa caggttagta agatagagtt aaatccacat actgttgatt
    12361 gttttgtatt ttggacaaag gatgtaactc caatgttata tgatttaaat aaattaaaag
    12421 actataaata ttattttcac tatactataa catcatatgg aaaagaagta gagacatgta
    12481 ttttagataa aagaaaggta atagattcat ttaaggaatt gtctagaaaa ataggcaaag
    12541 aaagagtaat tttaagatac gacccgattt tcttaagtga aaagtacaca gtagattatc
    12601 atatcaaagc atttgcgagt ttatgtaatc agcttgatgg atttacagaa aaatgtataa
    12661 taagttttat cgatttatac aagaaaacaa aatttaatac taaagcatta catataaagc
    12721 caatagaaat tacagaaata gaaacattat caaaagagat ttctaagatt gctcataagc
    12781 atgggataac acttgaaatg tgttctgaag aatataattt aagtaaattt gggattggaa
    12841 aaagtaagtg tattgatgat agattaatat caaaaattat aggatgtgaa gtagaggtaa
    12901 aaaaagatag tacacaaaga gatatttgtg gatgtgttaa aagtgtcgat ataggacaat
    12961 acaatacttg cagacattat tgtctgtatt gttatgctaa ctttaattat gcaaaagtag
    13021 aagaaaactg taggctttat aaagaaggta ataaattact catagatact ttaagagatg
    13081 atgcaaaaat aagcattaga gatatgaaga ctattaaagt agataagaat aaacaaatta
    13141 gtatatttga ttaaaataaa tatactaatt accttaatat attaagaata tagatacttt
    13201 tgataacaaa attaaactta atagatattt tctatataag aaagatggtc ataatatgtc
    13261 aatttgacca tctttttgat ataattaaaa cacaaataat ttagtaacaa aggaggcaga
    13321 acttgaattt attaaaaaaa tatcctatac ctattgcaag tttgattttg tcaatcttta
    13381 ctttaggtaa cttattacaa tcttatagtg aatcattacg taatgtaatt ggatttatag
    13441 gatttatttt gtatgcaatt tatatagtca aaatagtatt acttagaaag ggtgttaaag
    13501 agcaattaga gaacccttta atatcaagta catttccaac tataacaatg gcaacaatga
    13561 tatttgctac atatataaaa ccattatctt tagaattaag tattatgatt tggagcatag
    13621 gaattgtggg tcatcttgtg ttaatagtct tatttagtaa gaagttctta gttaaattct
    13681 caataaaaac ggtatttcca tcttggtata tagtatatgt tgggatagtt gtagctagtg
    13741 ttacggcacc agcatttaat caacttttga ttggcaaaat tgccttttgg ataggatttg
    13801 tatcttatat agttcttata ccagtaattt taaagagagt atggataatc aaggaaatgc
    13861 ctgaaccatc tttaccaagt atagctatat tagctgcacc agggtcacta ttattgtctg
    13921 gatatattaa ttctttttca gataaaaata atgtagtatt atacttgtta ttcatattat
    13981 caattgtatt ttatattata gttttgggat atttaccgaa attattaaga ttgccttttt
    14041 atccgagttt tgctgcattt acattcccta tggcaataag tgcaatgggt atgaaactaa
    14101 tgaatggtta tttaactaaa tcaggtcatt ttataagttg gatttcatat gcttctaagt
    14161 tagaagagat aattgctaca gtgattattt tatatgtttt agttttgttt attatatatc
    14221 ttagtaaatc tgaaactaca tctaaagcta aataagaatt attaaatatg tgtatttaat
    14281 aggaatactg atataaatat atgaagataa gataaaccat agaaacttaa tttagcttaa
    14341 ttttattgga ggaaaacaaa tgaaaacaaa agaagaatat ttaaaagaag ttagaaacat
    14401 atcagaagaa tattttagaa aaggagagtt tttttgctct gaagcagttc tccagacaat
    14461 aaatgatgct ttaggccaac ctttaagtcc agagataact aagttagcat caggatttcc
    14521 gataggactt ggaaaggcac aatgtctttg tggagcaata tctgggggag agatggcttt
    14581 aggtatagta tatggaagag ttcatggtga agctatgaat ccaaagatgt ttgagcatgc
    14641 taaaggtttg catgattata ttaaaaaaga gtatggtgca acatgttgta gagctattac
    14701 aaagaaatgg gatggtgata actttatgtc tcccgaaaga aaagagcact gtattaaaat
    14761 aacaggtcaa gttacagagt gggttgcaga taagcttata gaagatgaaa aacttaatat
    14821 caaatagtgt aatattagtt ggtgaattta taaagttaaa tttacttata gtataagata
    14881 cttgatattc tcgtattgat agaaaaattt atagcatatg tatttaatga aatatactta
    14941 tatttagagt gtggtttaat ttcataaata catatgctat tattttaagt atataagcaa
    15001 atttatttaa ataaatagaa acagttaatt tatatgtaca aaactatata tgattagtgt
    15061 aaataaatac ctattttata atactcaaca taaagacacc agacatgatt agtattatac
    15121 caataaaaat agcaagccat tcttttttgt tcttcttttc tttaaaaaat ataatccctc
    15181 ctaaagtggc tactatcaca caactctgag agatagaaaa acttattgta actcccaatg
    15241 tattagtcgt tatgaacata cctaaatttg ctattgacca caatatacca gtaattaaat
    15301 tgaataaaac attttcccta tatacaatct ctttagaaaa atacttgaca ataatagatg
    15361 aagttatcaa cataccaaca gattgaggta atataattct atatccttca attaaaaata
    15421 tttgattagt tacaacatat aatgataaaa atagagatga taataataca actccaacac
    15481 attttaacat atttttatct gtagattttt tagtttgata atttgtgaga agtataccaa
    15541 gtattataca taatattgat aaagaaccaa tcagtaacat tttagaactg gtccattcat
    15601 taaacaagat tacagctaat aatgtcgtaa aagttaattg tgaaccattt gaaattggca
    15661 ttactttaga tacactagca atttgaattg ctttaaactg cattaattgt cccaaactcc
    15721 agaatatgcc agaaatcata cttatacaaa atgaaaaaat tgtaatttca ggatgtataa
    15781 ccagagttat tatagtggaa aatataaacg cacttatgga tgtacctaaa agctgttcat
    15841 gaggagaact tttctttaga tttgcaacta tgggcatcaa tccccatccc attacaggaa
    15901 gtaaagcaat aattattgtc agcattaaac tatttccttt catattaaat ttagacagct
    15961 tttaatttat catctaaaat taaagtgttc aatacataaa aattaccgta tttaatcagg
    16021 aaatattagt agttttttag aaaaacattt tccattaaaa taaagacaaa gggaaggagt
    16081 aaaattgaaa atgttaactg atatgattca aaatcgtgaa attaaaataa taaagttttt
    16141 attaaaagaa ggtcatacaa ctgtaaaagc aatagcagat gatttagatg tttcagaaaa
    16201 aacagtttca aaatctctta aagaagtaga agcagtgctt aaaaagatag gtctttcttt
    16261 aataagaaaa cctaagatag gtgtttatat tgatggagat ttaaaaaaaa tacttcctta
    16321 cctagataat aaaggaagtc aaattcctac aaccagagag gagagagtta tctatatata
    16381 ttcagtactt ttaaagagta atgattatat tactatacaa caactttctg atgaactata
    16441 tataagtcgt ggaactattg aaagggattt agcagaagtt gaaaaactgc taaaaaacga
    16501 agggatttcc atatataaga aacctagtaa gggaataaag ttaaatataa gtgaaagaga
    16561 taaaagacaa cttactgcta agtttataca taaattttgg agtagaaact ggtatattaa
    16621 gcaagagcaa gaaagctttt atcaagcatt tgaaaagata caggcagatg taaatggtat
    16681 tttttcggaa gatgatttat caataattat tgatattctt aggaatttca gcagagaaag
    16741 aaaatttgag ttctctgatt atgaatttca gtcattagtt attcatttgg caatagctgt
    16801 agagagaatt agaaaaggcg aatatataga agaaagtttg tatattggta atatagaaaa
    16861 taatcaaatg tcaaatacca attatttagc aaaacaatta gaagaaaaat tttcaatatt
    16921 attaccaaaa tctgaaattg gatatataaa tttacattta gtagcgtctg accaacatag
    16981 agatactaat gaactaaaaa atacttcaac taatccttgt gaaacaagta caaataatat
    17041 atcaaatctt cgggaaatta taaaaaatac attgtatgag acagcttatg acaaggattt
    17101 aattgatgga ttgacttcac atgtacattc atcaataaat agactgaaat atggacttag
    17161 tattaaaaac ccatatgtaa atacaatcaa acaaaacttt tctttatcat ttgagcaagc
    17221 tttagattta aagaaagtaa ttgaatttat atatgatatt aggataaatg atgatgaatg
    17281 tgcttatata gcattacatt ttgaagcttt tagagaaaga atgaaagaac ttccacaaaa
    17341 tattagagta attctagtat gcagtacagg attaggttca tctaggttat tgtctgcaag
    17401 aataaaaaaa tactttccaa tgataaagat tgaaaaagta ctttccgtac aagaattagt
    17461 atccagtaaa attgatgcag atttagtaat aagtactatt tatttagagt tagaaacaat
    17521 tccaaccata gtagttagtc ctattttaaa tgaaagtgat ataagaacct tggaaagaaa
    17581 tatacaaaat gtttcatgtt gtacttctaa gaagtataaa tctttcagaa atttaatctt
    17641 tgaagaaaat atattgttga atattgaaac ttcaaattat gaagatgcaa ttaatcatat
    17701 aacagataac ctaataaaaa aaggttttgc aaaagaaggt atagctaaaa gtgcaattga
    17761 gagagaaaat ttatcttaca cttctttcca atcaatagct acacctcatg ctaatcctag
    17821 ttatattaaa aaatctaata tatctgttgc aacgttaaaa aatcctatta catggggaaa
    17881 tgaaaaggtg gaagttattt tctttatttc attagaaaat gacaaaaacc tagagcttga
    17941 tgaaatatat gaagtttttt atgacttcat tgacaataaa aaaaatataa atgacatatt
    18001 aagtgcaact tccacaaagg aagtgtacga tttgctagtg gaggagagta tatagtgaaa
    18061 atatcagatg tattgaaaaa agagcaaatt gtttttaatc ttgatacaaa tacaaaggaa
    18121 gaaacaataa aaaaattaag tagtatattt gttgaaaatg ggattgtgga caatgaagaa
    18181 gaatatgtta agtctgtttt ggaaagagaa gaacattcaa ctacaggtat tggtaatggt
    18241 attgctattc ctcatgggaa aagtaatgct gtcaaaaaat cttctataat atttgcaaag
    18301 actaagcata agattgaatg ggatgcttta gatgaaaaac cagtagatag tattttctta
    18361 ttggctataa gcaatattga taaggatagc aatcatcttg tactattatc taaattagca
    18421 actaaactta tggatgatga caatgtagat gcactaaaat tagccaattc agaacaagaa
    18481 ataatcaata tatttagtga agaaggagag atgtagaaat gaaaagaaaa attatagcag
    18541 ttacagcatg tgcaacagga gttgcacata catatatggc agctcaagcg ttaaagaaag
    18601 cttcaaaaaa gatgggtcac cttataaaag ttgaaacaca aggagctaca ggaatcgata
    18661 atgagttaac tacaaaggat gcacaaattg cagaagtagt aatatttgca gtagatacta
    18721 aagtcagaaa tgctgaacgt tttgagggaa aagaaatact agaagtacca gttaatgcac
    18781 ctataaagga tgcagagaaa gtaataaatg atgcactaaa gttaattgac actaaataaa
    18841 tggagggaaa tataatgttg aaaaagatag tctctgagtt aaaaaagcat gtcttaactg
    18901 gaatctcata tatgattcca ttagtaattg caggtgctat gataatggcg atatctcgtg
    18961 taggtggttc tttctataat ataccagata tatgggatgc taaatatgca gaaagtgcta
    19021 gtagtattgt tagattatta catgatttag atgggtttgg aggtactgca ttaggattaa
    19081 tgtttcctgt aattgctgca tttataggat tttctatagc tgataaatta gctattgtac
    19141 caggccttgt tggaggtatg attgctaaag atataggtgc aggattttta ggagctttgg
    19201 cagttggtct tatagcagga tatacatgtt tgtttattaa aaatcatgtc aaattaccaa
    19261 aatcagcagc ttcaatagta ccaatattta tagtaccagt atttgggaca ttaatcactg
    19321 ttgtattaat caattatgtg ataggtatac cttttgccac attaaatact ggattagaaa
    19381 attggttaaa tggattatct ggtacaaatc agatattaat ggcagctatt ataggggcta
    19441 tgatggcagt tgacttaggt ggaccagtta ataaagcagc tttaacaaca tcacttgcat
    19501 tattaacaag tggaatttat gcgcctaaca ctgctgcaat ggtaggaata gttataccac
    19561 cactaggatt gggacttgct actatactag caaaacaaaa atataataaa cagttacgtg
    19621 aagctgggaa atcatctctt ataatgggtt taattggagt aagtgaagga gcaattcctt
    19681 ttgcggtaga atctccatta aaagtaatac cttcatgtgt aattggaaca gcaattgctt
    19741 cagctatggc agttggttta ggttcagtaa atgcaactcc aattagtgga ttttatggat
    19801 ggtttacagt agagaattgg ccaatgtatg tgttatcaat agcagttgga acagtaattg
    19861 tagctggatt agttatagta ttgcgtggaa atccagtgat tgaggatgat gaatttgaag
    19921 atgatgattt tgatgaagca gagtgggaat cttaaaattt aataactatt taagacgtgt
    19981 tataagctat attcaatatg aatcttatac taaataaagt gttaaacatt cagtttagac
    20041 ttaaatataa aagataaaga acagaggaga ataaatgata aaagcacata ttgttaatca
    20101 tacacactgg gatagagaat ggtattttac ttctggagat gcattagtac ttagtgaaca
    20161 actatttaca gatgtaattg atgaattaga acgtaatcca gatgtaagtt ttgtacttga
    20221 tggacaactt tctattttgg atgattatgt acaattacac aaagaaaaaa tagaaatcat
    20281 taaaaagtta ataaaagaag atagactaca tattggacca tggtttactc aaactgatgc
    20341 attctttgct agaggagagt ctattttaag aaacttaatg attggaattt ttgaaagtaa
    20401 aaagtatggt aagtatatga aaattgggta tttgccagat acatttggat ttaatgcaca
    20461 gatgcctata ctattaaagc atgtaggtct tgataatata ttcttttgga gaggtataca
    20521 tcttggtaaa caggttcaat caccatattt taagtggaaa agcttaaatg gagaaagtta
    20581 tatatatgca gtaaatatgc cacatggata tggaactggt atgcttttag agccttcatt
    20641 aaagtatgtt aatggacgct tagacccagc tattgatttt attaaatcat atactgatgt
    20701 agatgaggtg ttaatacctt ctgggaatga ccagttaaat ataataggtg atttcaaaaa
    20761 taaaattaaa gcgattaatg atatcggaaa gtattcatat ataacgagtt catatcaaga
    20821 gtttttaaaa tatataaagt ccatagaatc actagaaagc tatagaggtg aatttagaga
    20881 acctgtatta gcaagaatac ataaatcaat tggttctagt agaatggata taaaattagc
    20941 atgtgataaa ctagaaaaca agctgattaa aagaatagag ccattattag taattgctaa
    21001 aaagagtaaa attgaaataa gcaatcagtt acttataaat acatggaaaa aacttttgga
    21061 aggacaagca cacgatagtt tagctggatg tgtaactgat actgtaacag atgatattct
    21121 tcaccgtata agagaagcaa atgaaatatg tgacagtatt gaaaatacta ttgtaaaaaa
    21181 gatttcagaa gggcttaaat tatctaaaaa tgatatttta gtatttaata cagaagctaa
    21241 gcgttttaat ggatataaag agatacaagt tgtaagtgat agtaaaaata tttattttaa
    21301 agataattta gatgctacta taattgaaga aacttatgta aaatcgagag aaaatgtatt
    21361 agaagaaaca cctgctggta atatatttat tgaagaacca ggatattata tattaaaagt
    21421 aagaataaat atacagcttc ctgcacttgg ttataaagtt gttagttttg aatcaagtga
    21481 taaagaaatg gtgtcacttg ataaatctaa tgacactttt atatctaatg ataattataa
    21541 gataatatat gaagatggaa gcttaaattt acaacttaaa gatggaactt acatatcaaa
    21601 ctttttaaca ttaaaagata gtggtaatgc aggtgatacc tatgactttt ctccactaaa
    21661 aaatgatgag gatataaaac tttcgtttga taaagtgtat acagaaaaag ctttaggata
    21721 tgaaaaaatg gtggttaaag gtactacttt actaccactt acattagaag atagaaaaaa
    21781 caaatatctt aatgggaaat taaatgtaaa agtaagtatt gtcttatcca aagaaaaccc
    21841 attgatggat gtaaaacttt gtgttgataa cacgatatat aatcatagac tacgtgttca
    21901 tataaaaact gatataaaag ataataaaaa catagcatca ttgccatttg gatatataac
    21961 aagaaaaaat ggagttttag acaactggga agatatttac agtgaaatgc ctatagattt
    22021 agaacctttg gaaagtaata ttacgcttac aaaccaaaat agaagttgta ctgtatttac
    22081 tagaggaata aaagagtatc aacatattga agatgaaatt gcattgacct tacttgctac
    22141 tacagatgaa ctaggaaagc ctgatttatt atatagacca ggacgtgctt ctggtgatac
    22201 aactaaaaaa ggtcatataa gaattaaaac agataaagct caaatgctta aggaattaga
    22261 attttcattt gcaatatata tggattctaa atcatttgat gaattggaaa ttgcgaattt
    22321 aacccacaat tatctaaggg aatgtgtaaa ttatcaatta caggattaca atttcttttt
    22381 atatcgtata gataataaga ttcaaaaatc aattgtcaat aaaactgtaa gtagagaatt
    22441 agaaataata tctttaccaa aaaactatct tatatcagca tgttatcctt cttattacag
    22501 taaagataaa tttataataa gagtggaaaa tccaagtagt aatagaatga tattggatga
    22561 gcaaatattt aaaaatagaa atgggaaaat tgtaaatgca atagaagatg tagaagaaga
    22621 acaggtatat gaaatagcac cttttgacgt tatttcaata ttattggatt tataagtgta
    22681 aaagtaagtt tattgtttaa agtctgacag atattaatct gccagacttt ttaatttgta
    22741 taaatttggg taaacattaa tgaatggttt tagtatttaa gtatgaattt agtatttaat
    22801 atagaattta ttgaagtaga ataattagtt taacaggata agcagtttaa ataaagaatt
    22861 attatattag agtgatttta tatataattt aaaataataa aattttaata aaatgagtta
    22921 aagattgtat attaatagag ttgatgtagt tacaaaaaag ttaccaattg ttatgtattt
    22981 acaaaactga tatattaatt acataaaatc taaaatagtt tgtaatatga gtatatataa
    23041 taaaaatttt aattaaataa agctaggtat atttataata ttaataaata tattgctata
    23101 aaagtttgtt taataaatta aataaagaaa agaggagaat aaaatgtaca acatagatga
    23161 tatgatatat aattgtccag tagaagcttt atcaaatatt ttaggtaaaa aatgggtggc
    23221 tataattata tggaaaatac aagaagataa aaaacgattt ggagagctac aaagagctat
    23281 accagactgt agtaagaaaa tgttagttca acaactagat tttttaattg aacaggggat
    23341 tatagtcaac caaaaaaagt tggttaataa tgttgtagag tcaacatatt ttttaagtga
    23401 atcaggatta cgattgcttc ctgtcatgga aaaaatgatt atgtggagca ataaaaattt
    23461 aaattgtgat aaatactaaa atttactctg taagtaatga aaatttaatt aagctatgag
    23521 tagaaaaatg tattaaaatt acataatttt ttagttagat tttaatttag aaatgggatt
    23581 gtaatattgg aaataaaata aggaggaatt ttaatttgca aaatgtaaat ttatttttag
    23641 tatttataga aggtatagta tcattctttt caccatgtat actgccaatt ttgcctattt
    23701 atttgagtat attgtcaaat agtagtgtag aaaatttaaa agaaggaaag acgagtttta
    23761 taggaagttc tttatttaaa aatactatat tttttgctct tggaatctca acaacattct
    23821 ttatattggg ttcatcagta aaagtattga gtatgttttt taatgaaaat aaagatttaa
    23881 taatgtttat tggtgggatt ataattatta tcatgggatt attttacatg ggaataatta
    23941 aatcttcaat attgaataga gaaaaaagat ttaatgttaa gtttaaagaa atgaaagcaa
    24001 taacagcttt tatattaggt tttacgttta gttttggatg gacaccttgt attggtccaa
    24061 tattggcatc tgtattagtc atggtttcaa gttcaagtaa tcatcttagt gcgaatcttt
    24121 taatagcagt atatactatt ggttttattt tgccattcat aattacagct atgttttaca
    24181 gtaaactatt taaaactata gataagataa aatctaacat ggaaattatt aaaaaaatag
    24241 gtgggattat acttatagta tcaggaatat taatgatggt aaatggattt ggaagtataa
    24301 gcaaacactt taatacgtca caaaatagta aaattgaaag caagcaagaa gaaaataagc
    24361 gagaaaattc tactgataaa gaagaaaatt ctgatggtaa tgatagtcaa aaagactcta
    24421 ataatgacaa taatgataaa gggtctaatg atgaagatag aataaagtct attgatttta
    24481 ctttaacaga ccagtatggt aaaacacata aattaagtga ttatgaaggc aaagttgtat
    24541 tcttaaattt ctgggctaca tggtgtcctc catgtaaaga agaaatgcct tatatagaac
    24601 aactgtataa agactataat aaaaataatg atgatgtagt aattttagga gtagcttcac
    24661 ctaatttagg tagagaaggt tcaagggaac atgtagttaa cttcttaaaa gaccaaggtt
    24721 atacattccc tgttgtactt gatgaagatg gagcattagc atatcaatat ggaattaatg
    24781 cttttccaac tacatttata attgacaagg aaggatatgt aactcagtat attccaggag
    24841 ctatggataa ggcaactatg gcatcattta ttgaaaatca gagaaataaa taaaagtatt
    24901 taagtataag tttataaatc aatttaaggt tacaaaaaag tgcctaattg tgccacctaa
    24961 ataatcttgt tatagtaaaa gtataaacaa tacaagaaag ggttgaattt tatatgaaaa
    25021 aaacatttga tgctataata ataggatttg gaaaaggtgg aaaaacatta gcaggggatt
    25081 tggcaaacag gggattaaaa gtagctttaa tagaaaagtc aaacaagatg tatggtggaa
    25141 catgtgtaaa tgtggcatgt ataccaacaa aaagcttaga aaattcagca aacagcgtaa
    25201 aaacaaagaa tataaattct tgggatgaag tacaagctga atatgagaaa gctatagata
    25261 aaaaagaaac tttaattaca aaactcagag aagctaacta taataaatta aattcaaatg
    25321 agaatgtaac tatattcaca ggaatgggaa ctttcattga tgaaaaaaca gttcaagtca
    25381 aaactgaaaa tgaaatttat gagttagtag cagataatat atttattaat actggttcaa
    25441 gaccatttat acctaatatt aagggaattg aaaataagaa tatagtatat gatagtgagt
    25501 ctcttatgaa tctaagagtt ttacctaaaa aaatgacaat tataggagct ggatttatag
    25561 gtttagaatt tgctggtatt tatagttcat ttggagcaga agttacaata ttaaactcta
    25621 ataatggcat tttaccaaat gaagatgttg aggattcaga agaaataata aaattacttg
    25681 caaagagaaa tgtaaaaatt gttaataatg caaatataaa agagattaaa gaagtttctg
    25741 aattagcaat agtagaatat gaagtagatg gtaaatctaa agaattaaca agtaatatga
    25801 tacttgtagc tacaggaaga aaagcaaata ctgaagggct agggctagaa aatgcaggta
    25861 tagaattaaa tgaaagagga tttattaaag tctcagaaac tcttaagact aataaagagc
    25921 atatatgggc tataggagat ataaatggag gtccacaatt tacttatatt tcattggatg
    25981 attatcgcat agttattaat cagttatttg gagataagac tagaacaact aatgatagaa
    26041 agaatatccc aaattctata tttataagtc cagcattttc aagagttggt cttaatgtta
    26101 aacaagctaa agaaaaagga tatgaagtat tagtggcaaa gatgccagta gaagcaattc
    26161 caagagctaa acagattggc aaggcagatg ggtttataaa aatagtgata gataaaaaat
    26221 ccaataagat acttggagct agtatgatat gtgaaaattc aagtgagatt atccatctta
    26281 ttcaattagc tgtagattta gaagtagagt atacatattt aagagaccgt gtttatgcac
    26341 atccaactat gacagaagct cttaatgata ttctatctcc taatatgata aaagaagtat
    26401 aacataagtt taatatataa atctaaaatt atcattataa gtagatttta gaaagaggct
    26461 atctcaaaaa atagagataa gtctcttttt tactgtttaa ataataaaaa tatatttgat
    26521 tttataaaag aagattatct tatgaactaa aaagtttatt ttaaaacact acctatttat
    26581 gttataaact tataaatata atatagaatc tattattctg tattattaag tggggttaag
    26641 cgttataatt aattataaat attgaataat ctaaatggat aagataatgg tattaaaaat
    26701 tatcttaaaa ggtgaaataa tctgtattta atgtagtaca gttatatctt taaagcaagg
    26761 tggtgaaatg atataaataa gatatctaaa agagggtttg atgatagtga taaaagatgg
    26821 ttttcaagta aagaattaac aagacttata aaggctaaag aagaaataga atggttatta
    26881 aatagggatt acaaaataga cccagtcgtt acttttgttg gtgatagata tcagttttct
    26941 ataagacaaa gagatgcatt aaaaagagca gtctgtactg atgaaaaaaa tattataaga
    27001 caatcaaaga ggctttctct agataaaatc aaagaagata ccgtaaatat agatggcttt
    27061 aatttgataa tatccataga ggtaggatta tctggtggta ctctagtaat aggaagtgat
    27121 ggcaatataa gagatttagc aggtcttagg ggaacctata agattataga taaaacagaa
    27181 gaagctttga atctgatagg taaatttttt aataaataca atgcacagaa tcttaaattt
    27241 tatttagatg ctccagtttc taattcagga aatttaaagt ataggatatt agagcatgcc
    27301 aaaacttggg gaattgaaac tgaagtagaa ttagtaaaaa atgcagatgt tgtattggaa
    27361 aaattagata gagtagttag tagtgatgca gtcatagttg acaagtgtat aagttatttt
    27421 aatgtggcta gaggtataat tgaagagtat attaaagaat gtaatatcat aaatttaaat
    27481 aaatagataa atataggtga gaatatataa gtatatgtag caatattatt agtaatacaa
    27541 gtaaagtttg aaaataggag aacgaataca tatcgaattt cataaaatgt tgtaaaaaga
    27601 catatgagag gatggatatg tgtgaaatta actaaactaa atattaaaaa atatagagca
    27661 cctatatata aatatgcttt agcaaatgta aatttgaggt ctgctaaatc tactaattca
    27721 agtatcataa cagtaatacc tcagggagct aaaatggaag tattggatga agaagatgac
    27781 tggattaagg tgatgtacaa ttctcaagaa ggatatgtgt ataaggattt ggtatcagta
    27841 agcgaatatg cttggagtaa cttaaactta agagaagata aatctacaac ttccaatata
    27901 attacagtaa ttcctgaaaa atctagggtt gaagtccttc aagtagatgg agattggagt
    27961 aaggttgtat atgatgataa aataggatat gtttttaatt attttttatc aattgatggg
    28021 aataaaccaa atgaattaga ttataagtat ttttatactg acatgattaa atttgttaac
    28081 gaaaataata ttaaaagtac tagcgattat ctaattgtaa cagaccttag aaataaatat
    28141 acttatattt ttaagaaaga taatggagga tggggacaac tttacaagtg gcaatgtact
    28201 ataggcaagc ctgagactcc aactataaca ggtatatttt atataagtgg aagaaaacct
    28261 tcttttggaa cggatgagta ttcagttaag tatgctacta gaattaaagg tggatattac
    28321 tatcattctg tactatatga ttcaacagga agttatataa tagatggcag acttggtgaa
    28381 gctcttagtc atggatgtat aagattaagt acggaaaatg caaagtggat atatgataat
    28441 ataccagata caacaacagt tataattcat taagaaaaat tttgagtttt ttattgggat
    28501 aataattctt aaattaatag gattatatat taacttctca taaagagtac tatttaaaaa
    28561 gtgtaataag agagtgctat taacaaaaca aagatatttt gaggcactct cttataaata
    28621 tacataatta agatattttc ataaacaatt ctataatctt atctttatca aagaaaacag
    28681 gattagcacc agcacaagca tctttcatag agttttctgc aagcaattca aaattaggat
    28741 tatcaacacc tacatctttt aaagattttg ggattccaac ctcttcagaa agagctttta
    28801 tcttatctat tacaaagtca acacactctt tatctgattt attatttaca tccattccaa
    28861 taacttcagc tattggtcgg aatttggcag gggctgattt agcattttcc tcctcaacta
    28921 ttggaagtag catggcatta catactccat gaggtaaatc atataaacct cctaattgat
    28981 gagccatagc atgtacattt ccaagacctg cattactaaa ggcaattcca tttaaaaaac
    29041 aagcataaca catttgttct ctagcttcta tgtcattacc atttttaaca gctcttggaa
    29101 ggtatttaaa tatctgcttt atagcatata aggcagttga atctgtaaca tcataagcac
    29161 cattagctac tacagcttct atagcatgag ttagtgcatc cataccagtt gctgctgtta
    29221 aattagatgg tttgctaatc attaattctg ggtcatttac tgtcattgta gctagtgaat
    29281 tggtatcaac cattatcatc tttacatgtc tgtcttcatc agttataaca tagtttattg
    29341 taacttcagc agatgtacca gcagtagtag ttatagctat gataggaaga cattttttag
    29401 aagttttgtt gataccttca tagtctctaa tatctcctcc attagtggct aatatagaga
    29461 tagctttacc acagtcttgt ggagaaccac ctcctatagt tataacgaag tcgcaatttt
    29521 ctgattttaa tattttaagt cctttattca cattagttac agttggattt tgtttaactt
    29581 catcataaac aacaaagtct atatctatct gagataaaat atctgttact ttttttacag
    29641 taccatttga aactagaaat ttatcactaa caataaatgc ttttttagtt cctaatgatt
    29701 taattgaatc tttagcttca ttaagacatc ctttcccaag taaatttatt ggtggtacat
    29761 aataaatgct cataactaaa atctcctttt attttcattg atttttatgt aaaaatatat
    29821 atctaacaat tttcactaat ttactcataa tatatcgtat cttagattga gatagggttg
    29881 ctggttctta tataagaact taatttgtaa ttacgattat gattagaatt taacatagta
    29941 tttttatcat gtcaataaaa atataaaaaa tattataaaa aaaacaaagt tactgtagtt
    30001 aaatcagcaa ctttgttttt atagtataaa tcaaataaat acattagttt aaaacaaaat
    30061 ttttaattat tatgttttga tatcttccat atacagaata ttaatctaat ttattacaat
    30121 gtcttcatta cgttcttcca tcattgattg aatatttttc tgagcattta agagtaattt
    30181 ttttatcagt tctatttttt cgtcattagc tctaaataaa ggcagtgtta cactaacagc
    30241 agctcttata catccatttt ttcttattgg tacggcaaga cattttaggt gttccattga
    30301 ttcctcacac tctgaagcta tttgtgttct ttgaacttca agaagctggt cgtataaaac
    30361 atcaaaatct gtaattgatt tttctgtaaa accttttaga ccatctggat ataagcttat
    30421 tagtttttcc ttgtcaaaat cacataaaag agcttttcca agacctgtac aattagcagg
    30481 tatttttttt ccaacataag aaataagtct aattggttct ggagaatcta cttttccaat
    30541 ataaagaact tcattattgt caagtatacc aagctgacaa gtttcagaac aggaattaac
    30601 tatattagtc atttcgtcaa ttatatagtt aaaaatagtt cttttttcaa aaaatgaaga
    30661 ccctaatgtg taagaacgta tccctataga atatttggat gtgtttttat caatagtaat
    30721 gtattttcta gcattaagtg tatgaactat aggaaagatg ctactttttg gagcattgat
    30781 aacatctgct atttctgtaa gagtatatcc attttcggat tctgctaatg cttctaaaat
    30841 atctaatatc ctagctgttg ggcgatgatt atctgaagtc ataaatttcc ccctcttttt
    30901 attaatttaa agtattagaa tatgttgatt ttagcacact atacgatatt ttacaatgta
    30961 gaaaataaat atgtaaattt atatataaat aagctcttga tttagataca gatagatatt
    31021 tttttagact gtacattaag gaataactaa tttccaaaat atacctaaag aaagtaagtg
    31081 atatttagtt atataattta agtaaatata tgcaatagtt atttttatat gtaaatatca
    31141 aaatattatg aacttatatt ttatctattt tttacactgt ataaaaactt tatagttttg
    31201 aatactatat aattttaaat acgctgtatt tttgcatata aggaagtcat ttgataatat
    31261 acaaggtatt atcagaaagt ttgaaaaaat tttgacaaaa atttattttt tttattgact
    31321 cataaatagg aaaatgctat cattaattca aagattcgta attaaaaacc tagttcttaa
    31381 atgcgaaccg aaacggccgt tagaattaaa gctaaaaact taataagagt aattaaatat
    31441 catgttttag gaggattaac tttatgataa tggattttat taaaaaaatt cctgcaggta
    31501 tgatgatagt gccaatgttt atagcagctt tcattaatac cttttgccca gatattgtac
    31561 aaataggttc gtttacgaca gcagtatttt caagtgttgg gtctgcaact ataattgggg
    31621 ttcaactggt atgcttggga actcagcttc aatttagaga aatgccaaaa gttttaaaga
    31681 gaggtggtat acttcttggt tctaaatttg ctataggtgc tttgataggt atacttatag
    31741 gaaagctatt tggaatggat ggtgtccttg gtcttacaac attggctgtt ataagtgcag
    31801 ttacaaatag taatggtagt atatatcttt cattgatgac ttcatatgga gatgaaacag
    31861 attgtgcaac tatgagttta cttactttaa atgatggacc attttttaca ttaatagctc
    31921 ttgggacttc aggtcttgca aatgtaccat tgttgtcatt attggctgca atagtgccaa
    31981 tacttgttgg tatgataata ggaaattttg acaaaaaaat gaaagagttt ttagagccag
    32041 ggtgtaattt actcgtacct tttgtagggt ttgcacttgg tagtagcata aatcttgcaa
    32101 gtatactaaa aggaggttta tcaggagtat tacttggatt aatatctgta tttgtaggag
    32161 gtatatttat agtattctgt gataaattta taggaaaacg tccaggatat gcaggatggg
    32221 ctgtagctac aactgctgga aatgcaattg ctgtacctgc tgctgttgca ttagttgacc
    32281 catcatggca accatatgtt gcaacagcta caacacaagt ggcagccgca gtagttgtca
    32341 ctgcaatatt agtacctctt ataactagtt ggtgggctaa gaagtatgga tgtcctaagt
    32401 tcccaaaaca aaatgaggat ggtacaataa cagcttaatt tatattacag tgagttgttg
    32461 gtaaaataat aaattcttta attagatttt aggatattaa taaaattata ttatttataa
    32521 aggagagcaa gaataatgat aaatgcagtg ataattgatg aaaaagataa tgttgcagta
    32581 gctattgaag caatagctaa aggtagtgaa attagtttta aattaaaaga caaaacagta
    32641 aaaacgatta cagcactaga tgatataact atttatcata aattggctat aaaagatatg
    32701 gccaaaggtg ataaagttac taaatatggt gaacatatag gagaagcaaa tcaggaaata
    32761 aaaagtggtc aacatgtaca tattcataat gttagaagtg ttagagagga tttggataaa
    32821 caagttatga ctaatatata aaataatttt atagagttat aaaagttgta ttcattgctt
    32881 ttagtgtcaa atagttttta aataggattt tagctgtttg attagtgagt gtaataaaaa
    32941 ttataatata taaaaattat aaaaagtata tagactattt taggaggaaa tcagtatgaa
    33001 attttatgga tataaaagac cagatggaag agttggtata agaaaccaca tattaatctt
    33061 gcctacgagt gtgtgtgcat cagatacaac tagaataata gcatcacaag ttcaaggggc
    33121 agttaccttt aataatcaga atggatgttc acaagtacat tcagaccaac aattaactat
    33181 ggatgttatg gctggttatg cagcaaatcc aaatgtatat ggtgtaatag ttgtatcttt
    33241 aggatgcgaa aattgccaaa atgatttggt agttgatgca ataaaagaga gaacaaataa
    33301 gccaataaaa actcttgtaa tacaagaaga acatggaact ttaaaaacta tagaaaaagc
    33361 tgttcgttat gctagagaaa tggcacaaga agcttctttg cttagaaaag aagaatttcc
    33421 aatatctgaa cttatactag gaactgaatg tggtgggtct gacccaacaa gtggattagc
    33481 agcaaatcca ttaataggtg aattaagtga taaacttgtc gatttaggag caacatcaat
    33541 tttaagtgaa actactgaat ttataggtgc agagcatata ctagctagga gagcagtaaa
    33601 tgaagaagta aaagaaaaaa tattacatat agtacataga tatgaaaatt cattaaaatt
    33661 ggttggagaa gaagttagag aaggtaatcc atctcctgga aatatagctg gtggtttaac
    33721 aagtttagaa gaaaaatcac ttggttgtat acataaaggt ggtcatagac aaataagtga
    33781 agtatatgat tatgccaaac aaattgataa gaaaggtctt gttataatgg atacccctgg
    33841 aaatgatgct tcatctgttg ctggtatggt agcaggagga gcacaaatag tggtatttag
    33901 tacaggaaga ggaacaccat caggaaatcc aatagcacca gtaataaaaa taactggaaa
    33961 taaaataact tttgcaaata tggaagataa tatggatttt gatgctagtc cagttatata
    34021 tggtccacaa acaatggaag aattaacaga tgatttgtta aatatggttg tagatgtagc
    34081 aaatggaaaa caatcaaaag cagagtccct tggatatact gaaatggcaa tagctagagt
    34141 atgcaactat gtataatctt taagtaagaa aataaataca tagaatttta ataaagggtg
    34201 agattatgaa gtttttaagt tttactgaag gagaaaatga atgtaaaaga actggagttt
    34261 tttctaaaga tgaattattt attatagatg ttaactcttt aaatctcagt agaaatttta
    34321 aggatttaaa tgaattaatt caaaatgtat ctagtgaaga tattattaag ttgaaaacta
    34381 ttataaatga aagtacattc tataattatg atgtttttaa aagagagaga tgtacggtac
    34441 atgttcctat agaaaaacca atacatgata tcttatgtgt gggagtgaac tataaagacc
    34501 atcttgaaga aactcaaact cactttgatg atagttttga agaaccacaa aaaacggttt
    34561 attttacaaa acgtgtgaca aaggcaatag gtccagaaga tgagatagat ggtcattttg
    34621 agataaataa tcaactagac tatgaagttg aacttggagt agtaataggt aaaacaggtg
    34681 ttaatattag aaaagaagag gtagaagatt atatctttgg ttacactgtt ataaatgata
    34741 tttctgctag aaagttgcaa aaagaacatg ttcaatggtt tagaggaaaa ggattagata
    34801 catttacctc tttaggtcca tgtattttac ataaaagtgc agttcctttt cctataaaac
    34861 ttaaagtatg tagtagggta aatggtgaag aaagacaaag ttctaataca ggattattca
    34921 tatcagacgt ttcagacata gtttcagaac tttcaaaagg tatgacttta gaggctggag
    34981 acattatagc tactggaaca ccttctggag tagggatggg attttcacct cctcgatata
    35041 tgagtagtgg agatgtagtt gaatgtgaga ttgagagtat tggaatttta aaaaattaca
    35101 ttaagtaact gttttaatat aattaatatt aaagctaaat ctgatgtatt aatgaacata
    35161 ttaaaataaa ttttaggagt ttaaattatg aaagcagaat ttttgacacc agttgttaca
    35221 atatttgatg aagaaggaaa tttagataaa gaaggtaata aaaaagtgta tgaccatctt
    35281 atagatggag gtgtagatgg actagtcata atgggaagta ctggagagtt ctttaatatg
    35341 tctatggata tgcaaaaaga acttatagat ttagtaacta gtcatgtaaa taagagagta
    35401 aaagtgttta taggtacaag tcgtatgtgt ataaatgaat ctatagaact ttcaaactat
    35461 gcacataata gtggagcaga tggcgttatg ataataagcc cttattattt ctctcttgat
    35521 gatgatagta ttgagttatt ttatagtgaa atagctaaga atacagaggc tgaaatatat
    35581 ttgtacaatt atccagatag aactggttat gatttaagtc cagaacttac attaagactt
    35641 gcaagaaaac ataaaaacat agttggatat aaggatacag taactttgat gggacatacc
    35701 agagatttaa taaatactat gaaaatagag ttcccagaat ttaaggttta tagtggttat
    35761 gatgaaaact ttatacataa tctaatgtct gggggagcag gttgtatagg ggggttatca
    35821 aatttaattc cagaagtttg ctccaaatgg gctgaagctt acaataatag agatatggag
    35881 aaggttatag aaattcaaaa atatattaat aaagcaatgg atttttactt aataaccaat
    35941 ccatttatac cagcaatgaa aaaagctatg aatatcagag ggttacaaat aagtgattat
    36001 atgactgctc catttgtaaa accaaatgaa aaacaagtat gtgaaattaa aaaattgatg
    36061 aatgaattaa atatatgtca acttactaag taagatatat atgagcaaaa aaagagtgtt
    36121 taaactgatt tttataatca ttttaaacac tctttttata tatgttaaat caactttgaa
    36181 aagtggtcaa caataaatta caattatgtt aataaaaatt aaataatact aagatagcat
    36241 attagtttaa aagttagcac aaatattaaa gcaatagcct ttatctatta aaaataatct
    36301 tggagtttta caaacatttt tagataagta taagttaaca ataagagcca catataaact
    36361 actacaaatc atgtaataat taatctaata aatgataaac acttagactt caagcttaaa
    36421 agtataaaga taaatgaatt tacatatcaa gattggcaat aattttgtga tacaaagcac
    36481 tatagcaaga atgatttaat accaatgatt ttgaaagaac atatagaaaa atacaattag
    36541 aataaaataa attttagagg gaaggcattg ccttccattt tttgtgtttt tctagaattg
    36601 ggtaaatttt acgattctag taaagcacaa aagaaaatct gttggtcttg aacattttat
    36661 attagtaatt ataggtagca atatacaatt actacaaaag tgaaatatta atgaaatgta
    36721 aatcaattta aaaaaattaa attaaaaatt acaatagata tataagaaat ttaaaggaga
    36781 aataaggcat gaaaaatgta ttaagtgttg aaaaaataga aaagtattat gaaaacaaag
    36841 ataatattac aaaagcaata gataataatg atattacaag attaaaattc aaaaacttag
    36901 ataaatttag acaaaatgaa ttaggattta tattccaaaa ttttaatctt ttatatactt
    36961 taatagctta tgaaaatata gcattgacat taacaattaa agggaaaaca atataaattt
    37021 gattcaaaag catcaagatt attacttgag agttttgaaa gtttaaatca agatttaaaa
    37081 acaacaattt taatgctaac taatgatgct tttatagcta gttatactca tagaaactta
    37141 tttataaaat acagaaaaat atttatagag ttagcaagac gaactgattc aataaaagag
    37201 tcttttaata gaataattga agaaatagct ataatcagag gagatgataa caatgtattc
    37261 taaaatagcg attaaaaatg ttagaaaaag ctttaaggat tatagtatat attttttaac
    37321 tttaacatta gtaatttgta ttttctatag ttttaactct atggaatctc aaaaagcttt
    37381 aatggaaatt agtacttcaa aaaagcctga tttagaaatg tttaagaata tgatttcata
    37441 tatatctgtg ttcgtatcag ctattttatg tactttaatt ctttatatta ataacttatt
    37501 aatcaaaaaa agaaataaga aacttggaat ttatatgact ttaggaatgg gaaaaattga
    37561 aatgtcgaaa atattagttt ttgaaactat aatagttgga atagtctctt tggtaagtgg
    37621 gctaatactt ggattattag tatctcaagg gttattaata ctattattaa aattatttga
    37681 atttaatatg agtgaatata gctttgtaat atcaatacca gcaattatta aaactattgt
    37741 ctattttgga ataatatttt tacttgtaat gatatttaat atctatttaa tttctaaata
    37801 caaaatgata gatttattaa ttgtggaaag aaaaacagag gatataaaat ttaaaaatcc
    37861 atttgtatat atgattacat ttgtatcatg ctttattttc ttatttactg tatataacac
    37921 tacaaatcat atcataatta atctaataga tgataaacaa ttaaactcca agtctaaagg
    37981 tgtagaaata aatgaattta catatcaaga ttggcaacaa ttttgtgata taaagtatta
    38041 tggaaagaaa ggtttaatat caatgacttt aaaagaatat atagaaaaat acaagtagaa
    38101 taaaataaat tttagatgga aggcattgcc ctctatattt ttgtgttttc tagaattgag
    38161 taaattttgt tactctagca aagtataaaa gaaagaatgc tggtcttgaa tattttatat
    38221 tagtaattat tagggaataa tatataatta ctacaaaaat gaaacattaa tgaaatgtaa
    38281 atcaatttaa aaaaattaaa taaaaaatta caatagagat ataagaaaat taatttaaag
    38341 gagaaataga acatgaagaa tatattaagt gttgaaaaaa tagaaaaata ttatggaaac
    38401 aaagataata ttacaaaagc aatagataat ataagcttta aagttgatga aggagaattt
    38461 gttgggataa tgggtccaag tggtagtggg aagacaacac ttcttaactg tatatcaaca
    38521 atagacaatg taacaatagg taaaataata ataaataata atgatattac aagattaaaa
    38581 tctaaaaact tagataagtt cagacaaaat gaattaggat ttatattcca agattttaat
    38641 cttttagata ctttaacagc ttatgaaaat atagcattgg cattaacaat taaaggagaa
    38701 aaaccatcta aaattgattc aaaaataaga gatgtagcta catacttaga aatagaaaaa
    38761 gtgatagata aatatcctta tcaaatgtca ggaggacaaa agcaaagagt agcatcagct
    38821 agagcaatag ttactaatcc atcattgatt ttggcagatg aacctacagg agcacttgac
    38881 tcaaaatcag caagattatt acttgagagg tttgaaagtc taaatcaaga cttaaaagca
    38941 acaattttaa tggtaactca tgatgctttt acagctagtt atgcccatag aatcctattt
    39001 ataaaagacg gaaaaatatt tacagaatta gtaagaggag ctgattcaag aaaagagttt
    39061 tttaatagaa taattgaagt aacaactcta ataggaggag atgataacga tgtattctaa
    39121 aatagcaatt aaaaatgtta gaaaaagctt taaggattat agcatatatt ttttgacttt
    39181 aacattagca atttgtattt tctatagttt taactctata gaatctcaaa aagctttaat
    39241 ggaaatgaat gcttcaacaa aatctcatgt agaaatgctt aagaatatga tttcatacat
    39301 gtctgtattt gtatcagtta ttttatgcag tttaattctt tatgctaata acttcttagt
    39361 caaaaaaagg aataaggaac ttggaattta tatgacttta gggatggaaa aagttaaaat
    39421 atcgaaaata ttagtttttg aaactataat agttggaata gtttctttag taagtggact
    39481 aatacttggg ttattagtat ctcaagggtt atcaatatta ttattaaagt tatttgaatt
    39541 taatatgagc gaatacaatt ttgtaatatc gatatcatca attattaaaa ctattgtcta
    39601 ttttggaata atgtttttac ttgtgatgat attcaacact tatataattt ctaaatataa
    39661 aataatagat ttattaacaa taggaagaaa aacagaggat ataaaattta aaagtccatt
    39721 tgtatataca attacattta tattatgcat tatttcctta attattgcat atagcatggt
    39781 tttaaaagtt ggattaaatc ctaaaaatcc taagtttatt atgtcaatag tattaggtgt
    39841 aattggaact atattattct tctatagttt agcaggcttt gcattatata ttgttaagaa
    39901 gaataagaac atttacttta agggattaaa catatttgta gtaaagcaaa taaatagtaa
    39961 gattaataca aactttatat caatatctat tatttgttta atgttatttt taacaatagg
    40021 aatactatca acagggtttg gttttaaatc agctttaaat gcaggactaa aaggtgcaac
    40081 tccatttgat gcaagtgcaa ccatgattgt acatgaaaaa tgtaaagtga agaatataaa
    40141 agaatctttt gaaaaggttg gaattaagtt taataaaggt gataaagttg cttactatga
    40201 tgaatatata aatggtaata aactttcaga tgttatgcaa ggacaatatt ctggtagagt
    40261 ggactttgaa gtagcatata taaaatcttc acagtataat gaaataagaa agttacgagg
    40321 tgaaaagtca ataactttat caaaagatga agtattaata acatctaatg ctacagaggt
    40381 agtaccttcg atagaagaat acatgaaaaa taataaaatt ataaaaatag ataataaagc
    40441 atataatata aaaaataaaa aagtaataaa agataattta agaactgatt ttacagaaac
    40501 aaatgctctt actgtagttg taaatgacaa attgtgtgat agcatggaga tatcttcaag
    40561 tatagtaaat ataaacttcg cttcagataa taatgaaaag tcacaagaaa attttgataa
    40621 aaggctaaaa tcaaagtata gttctacaag tttttatgaa gttggaactg tatcaggtgg
    40681 atcaagaaat gctatgtata atgataataa tggtatgact tctacaatac tatttgttgg
    40741 aatatattta ggaatagtat ttttaataag tagtatggca gtccttgcac ttcagcaatt
    40801 aagtgaggct agtgatagta tagatagata tgtatcctta aaaaaactag gagcaagtaa
    40861 aaatagtata agtaaaacta tatttacaca aactctaatg tactttagca tacctgttgg
    40921 actagcttta gttcactcag tagtaggaat acaagtggct aataatttta tatcaaggct
    40981 taataagcca gatataggag cttcatcact tatgacagta ggaattttaa tgttagtata
    41041 tgcagtgtat ttttatacaa cttatcaagg gtataaaaat atagttataa aaaagcttaa
    41101 ttaatacaac taactaaaat ctgtttacag taaaaatcat actgtaaata gattttttga
    41161 aaataaaggg tgaaaaatta atggaaaaaa taattatagt ggaagatgaa gaagtaatca
    41221 gagatgaatt aaaaagcttt ttagagaggt atggatatga agttatggct cctactgaat
    41281 ttgataatat agtagagttt atattaagtg aaaaacctaa tttagtatta cttgatataa
    41341 acttgccaat atatgatgga tattatatat gtagagtatt acgtaaagaa tcgaatatac
    41401 caataataat tgtaacaagt agaaacactg atatggatga actaatgagc atgaatttag
    41461 gagcagatga ttttgtgaca aagccatata aaacacaaat acttttagca aggattgttg
    41521 cattgttaaa aagaagtgga ttaaattcga atgtaaataa tactttaata tttaagggta
    41581 ttgaattaaa tttatttaat gcaacactca gatataaaga taaagaaata gagttaacta
    41641 aaaatgaatt taaaatacta tcttatttag tggagaatca aggttcaata gtatctagag
    41701 attcatttat ggagtatcta tggcacacaa attggtttgt agacgataga actcttactg
    41761 tcaatataac aaggctacgt aaaaagctag atgaaatagg catagaaaat ttgatagaga
    41821 caagacgtgg tttagggtat ataatatcat gagattaaga gagtatatag gtgataaagt
    41881 tgtttttcta ggtactaatt taattatatt tttaattgca tcaggtatca tgctttatag
    41941 taaaataaat gtcgttttaa tatttatgtt attttgtata tggtttttac cattatttac
    42001 ttatatgtta attgattatt tacaatataa gaagtacttt aattctatag ataatatttt
    42061 agatgcttta gataaaaaat atttgttgcc agaagttatt gatgatgtaa attttgtaac
    42121 tggagaaaaa ataaatgata ttttaaaagt aataagtaga aacatgcacg aaaatattaa
    42181 atattataat gataatcaag aagaatataa agaatatatt gaaacttggg ttcatgaaat
    42241 aaaaacgcct atagcatcta gtaaacttat tatagaaaat aatagtaatg agattactaa
    42301 aaagatagat actcaactag ataaagttga aaattttgtg gaacaagtat tatattattc
    42361 aaaaattgat aatgtaaata aagattatat aataaaaaag ctaaaccttg aagaagttgt
    42421 aaatgaagtt atcaaaagaa actatagaga ctttataaac aaaaatataa aattagaact
    42481 tggtgaaatt aataagactg tatatagtga ctcgaaatgg gttgagttta tattaaatca
    42541 aattgtggta aattctataa aatatataaa gtcaaaagat ggtttaataa aaataagtgc
    42601 aaaaagggta gaaaactcaa tagtgttaac tatagaagat aatggagtag gtatagtaga
    42661 gagagatatt aataaggtat ttgaaaaagg gtttacagga gagaatggaa gagtatttgg
    42721 aaaaagtact ggaataggat tatatctatg taaaaagtta tgtaataagt taggtttagg
    42781 tttaatatta gaatcaaaag taaatgttgg tacagtcata aaggtatcat tccctataga
    42841 ttacaattta ttttagtgta tagttataaa aactgacaat ttttagttgt cagttttttg
    42901 tatttattta agaaagttaa ggatgtaagc ataattgata ggttcttttt tttacttgat
    42961 tttcataaaa acgtattata tcattaattt agtagtaaaa gctgaaggga agtaattata
    43021 atgaaattag atagtaataa tcattcagtc ttcttattgc attatcattt agttatgtgt
    43081 ataaaatata gaagaaaagt aatagatgat tctatatctg atagactaaa agatatattt
    43141 gtagatattg caccaaatta tggagtggtg ttgatagaat ggaatcatta tgttgaccat
    43201 gttcacttat tattcaaagc aaagcctaat acagaaattt ccaagttatt aaatgcctat
    43261 aaatctgcat caagcagaag gataaagaat gagtttccaa gtatccgcaa atacttatgg
    43321 aaagaatact tttggagtaa aagttattgt ttagtaacaa ctggtggtgc aacattggaa
    43381 gatttggaac aatacataga aaatcaagaa gaatagtgat aatatgttaa gagcttataa
    43441 gtacaggttt atacaaacag tgaataaaag gaatcttttc ctaaaaattt tggatgtaac
    43501 ggacttatct atcaaagaaa attaactatc atagctatac tactaaccaa aatagtttgt
    43561 caacacgtta ctcaaaagat attgtgcata tagaaatggg tgtataaaac tgcttaaatt
    43621 aaaatcaatg attaggataa aacaacatag gcaatttgat agagttgtac tgtatctaaa
    43681 gcatcatcaa ataaatgtta tatttctatt agtttgccaa cgtagtgact cagatgctaa
    43741 tcgtaagtgt tgggaactat cctattagct tggagatact aataacaata gctattttga
    43801 ccaagaagat gtaacttcaa acgttgtcgt aggtagttaa gtgtataagt agttaattgc
    43861 atgtgaaatc aaaattcact ataattttat taaaaagtta tacttgttaa agatggttta
    43921 atataacttt aataagatat actttaaaag gtatatctta ttaaagtttt ttagccactc
    43981 ataaaaaata agatattgga gtgaaagaga tgaaatttaa atcaaatgtt ttaaagcagt
    44041 tttttttaat tgctatggta atttttatgg taggaggtct tatagggtgt agtaaaagtg
    44101 acaaagagaa taaacaagct agtactggta agaaattaga attaaaatat gctagtggat
    44161 ttagtgttga agatttagaa gatggaatta aaaaagtaac tgatggagat aatcgagaac
    44221 tgattttaat cccaaagaag attaaaattc ctgaaaaata taaaaatgct aatatagtta
    44281 gaacgcctgt ggacaatgta ttaatagcat ctacaacaca ggcttgttct ctgagaacaa
    44341 tagatgaact agatagtata aaagcagtaa caacagaaga gcagtactgg actattaaag
    44401 aaattaaaga tttaatgaaa gatggaaaaa tacattacgt tggttcaaat ttagcaccag
    44461 attatgaaaa aatagtagac ttaaatcctg acttaactat agtgagtagt ggtttatcag
    44521 aggctgatac aaaatttatt gacaaattaa aagaattagg gcttaattat gttgtagaca
    44581 atgagtataa agagcaaaat ccatttggaa gaatggagtg gacaagttta atagctgcat
    44641 tttatgataa agaagatatg gctactagtg aactaaataa aactgtacaa aaggtagaag
    44701 aagtaagtaa aaaaataaaa aacaaagcta aacctaaagt tgtatgggca tctgtatatg
    44761 aaggaagtgc ttatatagct cctaaagatt catatgtgga taatatgata aaaatggctg
    44821 gtggaataaa tgcatgtgct tcaatagatt caaatgaagg gcgagtaagt attgaacaat
    44881 tgcatgaagt tgcaaaagat gcagatatat ttgtatactc atcaagttca gattatgcac
    44941 caaatttaga ttctataaaa tctagtgcac ctgtattggc tgatttggat gttgtaaaaa
    45001 acggaaactt atgggtgttt gctccagatt attatcaatc agtagataag acagacgaat
    45061 taatagtaga tttagttgag atgttccacc caggtactac aggtgaaaaa atcaaacatt
    45121 atataaatta tgataaatag tacagagagg acacaaaaag ataggtttta tagattttag
    45181 ttaatatagc tttgctaaga ggagtataca aatggatttt atcaataaaa tgagaataag
    45241 gaatacgaca atatttatag tattaattat aagtatgata cttacttttt tagtgtgtgt
    45301 agcatttggc tctgtaaaaa ttgaatttaa agaagtaata gatgttgtat taagaggtat
    45361 ggataataca gaacattata aaataatata caatataaga atccctagag tacttgcaac
    45421 catggtaggt ggagcatgcc tagcagtatc aggtatttta ttacagatat tttttaaaaa
    45481 cccaatagtt gaaccgtata tattaggagt atcttcaggt tctactttat cagtagctct
    45541 catgattttg ggaggataca cattgggatt tgagagtgta aattcaatga gtatatttgt
    45601 agcagctttt ataggagctt taattgtaat gtctatagtc attttatttg caaataaggt
    45661 aaagaatata acaattcttt taataatagg aattatgacc ggatatgtat gtagtggtat
    45721 aacaaatgtg ttacaatcat ttgcaaatag tgataaatta aaagaattta ctatgtggtc
    45781 tatgggaagt ttttctggat ttacatggga aaaggtagaa atacttataa tagttggtat
    45841 attaggtctt ttgatgactg tattcataat aaaaccttta aatgcttttt tactaggaga
    45901 agagtatgca aaaagtattg gcataaatat aagatttttt agagttttga tagtatttat
    45961 atctagtata ttagcagcaa tagtatcagc atttgcagga cctatagggt ttattggact
    46021 tgcagtgcca caaatttcaa aattgatact taaaacatca gataatagag ttttgatacc
    46081 agtagtaata tttttaggca gtatagttac agctctttgt gatttaatat caagagtaat
    46141 tttatcacca gtagaattac caataagtac gataacatct ttattaggag ctccaattgt
    46201 agtaatgtta ttggtgaaaa ggaaggatag ggcttagaca tgttgaaaac taataattta
    46261 agtgtaggat acaataacaa agttgttata agtaatataa atgtagaagt aaaaaatggg
    46321 gaaatactat gtcttttggg aagtaatgga gctggaaaaa ctaccctatt aaggtcctta
    46381 tctaaactta tatcaccaat aaaaggtgaa atatatttga atggtgtaaa cataaattgt
    46441 atatcaagaa aagcattatc aaaaaaaatg gctttagtac ttacaaatag attattaggt
    46501 gatttaatga ctgtacaaga tatagtcaat ataggaaggt atccatatac aggatttttt
    46561 gggagtctat ctaagaaaga tttaataatg gtagatgaag cattggagtc tgtagatgcc
    46621 ttacatttaa agaaaagata ttttgatgaa ctaagtgatg gagaaaaaca aaaggtgttg
    46681 gttgcaaggg ctcttgttca agaaccagaa ataattatat tagatgagcc tacaactcac
    46741 ttggatataa aacatagatt ggaactcata aacatactga aaaaattaag taaagaaaag
    46801 tcaatatcag taatactttc attgcatgaa atagacatag cattaaaaag ttgtgataaa
    46861 gttgctctta taaaaaataa taaagtcata gcttatggcc agcctgaaga tgtagtagat
    46921 gaggatatta taaattcgct ttatgaattg gatgataaaa actttaatag tcttttaggt
    46981 tcagtagaaa ttagtaataa atctaaaaat gaagttttta taattggtgg tgggggtaaa
    47041 gcaacaccaa tttatagagc ttttactaaa aaaggtatag gtctgtattc tggaataata
    47101 catgaaaatg atattgatta tgaaattggt agaactatgg ggataaagat gtttacagaa
    47161 aatccatttg agcctataag tgatgagagt ttcggtttgg ctattagaaa tttaaatgat
    47221 tccaagatta taatagatac aggatttagt gtaggagaga caaataagag gaatatagat
    47281 attataaaag aggctttaaa attggataaa aaagtttatt cttttagaaa tagagatgag
    47341 agtaagaagt attatgacag tttggatagt aagatagaac atatagataa agtttctcaa
    47401 ataatcaata gtgcagatat aaataattta ttataattta tgaaataaaa tgtacttatg
    47461 tgctatagaa aaaagagtat agattataat ttttttgaaa ttacaatcta tactcttttg
    47521 ttattttgtt tatgtattta tatatttata aaactttagc attttataga taaccaatag
    47581 cttcctctct agttaaaaaa aagtgaatcc ctgtagttga ttctttccat ctattttcat
    47641 taaaatcttc agctacaatc gtttctccta ctctatatat aaaattttca tcagcatatg
    47701 cacgagcact tttaaaagat tctttaccat ctatactagt aattgacagt acttttgcct
    47761 tatcacatct acaagcattt gatgtagcag acactctttt tgcgtcgctg ggtattaata
    47821 attgtaccat tctaaaatta aaacattttt tatagcctat aaatgctcct gtttcaggac
    47881 aatacaattt aaaaaaacgg gtactttcat ctgatattac tccatttaaa gtagcatatt
    47941 ctaaatttga attttctaaa ttagctcctc taatatctga gttagataag tcacaaaatc
    48001 taaaacttgc accacttaag tctgcatttt ttaatataga attttttaat gaacaatccg
    48061 aaagataaga attattaaaa atagagtttt ctaaatctgc tttttctaaa tttaaattga
    48121 taaggtcaga ccacgaaaag tcaatattac ttaagcagta tcctcttaag tccatatttt
    48181 ctaatctgaa ttcttttaaa tctgcctttt ctccagcatt attgttttta agccataaat
    48241 aatgtttctc aagtgttttt tctaattctt gtttagaaat agttttcatt aaa
//
LOCUS       DAEORM030000027        47044 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.027, whole genome shotgun sequence.
ACCESSION   DAEORM030000027 DAEORM030000000
VERSION     DAEORM030000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 47044)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47044)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 47044)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47044
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.027"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            complement(81..1088)
                     /locus_tag="KRH23_002026"
     CDS             complement(81..1088)
                     /locus_tag="KRH23_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpoIVB peptidase S55 domain-containing protein"
                     /protein_id="HHS5225306.1"
                     /translation="MQLKNFHFKNNTLSKKTNLAKSKFTIVLTFLFLLYFFSNNLIYA
                     QNLQKNEPEYLIPIGNVLQIDAELKNIIVRNPGEASPFRLGDAIVKVNNAEVDGYSDF
                     ANTLNALPEEKQVSILLNRGGQLITMKTTKHILEKISFNNLLSGFATLTYINPDTSEF
                     GAVGHPISVGNARKIPIKTGSISTTKHLNIEKSYKGSVGCINAKRENIIGSFTENTDF
                     GIRGQINNFDISKLKKYKVASLDEVKLGKAQIILQDNFNKCKKYNIEIIDIENQKHPE
                     SKSFKIKITDKKLLAQTGGIVQGMSGTPIVQDNKIIGAVSHAIENDPAVGYGVFIKWM
                     L"
     gene            1316..2200
                     /locus_tag="KRH23_002027"
     CDS             1316..2200
                     /locus_tag="KRH23_002027"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008745 - N-acetylmuramoyl-L-alanine
                     amidase activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HHS5225307.1"
                     /translation="MKKYRLLVTCIIAMGIIIIGTSNPVSNFYKTTNLISSGNITNEK
                     ADKDENSNKNNKDKNEDKSNSKSNKDKSSEDKSSDNKNEIQKNKKLLICIDPGHQGKG
                     DSNLEPVAPGSSSKKARVSSGTEGIATKKPEYVLNLEASLVLKSILESKGYNVIMTRE
                     THDVNISNSERAILANDKKADMVVRIHADSLNNSSKTGASILIPEKDGKYTAPIYEES
                     NKCAEFIKQNMEQSGIQINGIVQRGDLTGFNWSKVPAVLVEMGFMSNYNEDQMMSNPD
                     YQRKMMQCIADGLDAYFK"
     gene            2402..3952
                     /locus_tag="KRH23_002028"
     CDS             2402..3952
                     /locus_tag="KRH23_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007788866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HHS5225308.1"
                     /translation="MLVVENVSHGFGARTILENVSFRLRKGEHIALVGANGEGKSSFL
                     NIITKKLMPDAGNIKWSSRATVGYLDQHTVLSKGKTIREVLREAFKHMFDLEQEMIAM
                     YDKMGEASDDEMSKLLEETAEIQTILENSGFYMIDAKIQEVANGLGLGEIGLDKDVTD
                     LSGGQRTKVLLTKLLLENPTILILDEPTNYLDEEHITWLTKYLQEYENSFVLVSHDIE
                     FINNTCNVIYHMENGELNRYKGNYDEFVRLNDIKKRQEEQAYDKQVEERKRLEDFVAR
                     NKARVATRGMANSRQKQLDKMEILERPKEKIKPTFAFKDARAASKIIFETENLVLGYD
                     EALTKPLNFHLERGKKIALKGMNGIGKSTLLKTLLGIIKPFEGNVKLGDYLEVGYFEQ
                     ESSRENSNTPMDEVWSEFPGLTNFEVRQALAKCGLTNEHITSQMRVLSGGEAAKVRLC
                     KVMLKNINFLVLDEPTNHLDVEAKDELKKAIKEFKGTVLLVCHEPEFYSEIVDDVWNI
                     EDFTTKIV"
     gene            3981..4628
                     /locus_tag="KRH23_002029"
     CDS             3981..4628
                     /locus_tag="KRH23_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HHS5225309.1"
                     /translation="MRKFLNVLFSVCISIVIIVGVINFTVGFKQLYYFDIDYLNISEL
                     SGLSKDDIKLNYDYLIDYNLNKNVSEFKLPTLKSSPQGKIHFEEVRNIFQNINKLAKV
                     LLVVSLVGIILSVKNKNIKILKTTSITLIIMPLLLTVPILLNFEKSFIIFHKLLFRND
                     YWIFNPDLDPVINILPEEFFFHSGMMILILILLVSILLFVMYKLCKSLSKKIFQC"
     gene            complement(4770..5030)
                     /locus_tag="KRH23_002030"
     CDS             complement(4770..5030)
                     /locus_tag="KRH23_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich small domain-containing protein"
                     /protein_id="HHS5225310.1"
                     /translation="MGENYKFFNHKDCEFFPCHKTNKPEEFNCLFCYCPLYALGENCG
                     GNFKYTDKGIKDCSSCILPHKKDNYNYIMSKFQDLVKITSKK"
     gene            5247..6530
                     /gene="hflX"
                     /locus_tag="KRH23_002031"
     CDS             5247..6530
                     /gene="hflX"
                     /locus_tag="KRH23_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HHS5225311.1"
                     /translation="MKEIQEKALLVGLNLTTIVKKNDDIDTNESMEELKELTKAAGAE
                     VVGSLIQNKHSVDAAYYIGKGKVEEIRAYSDSLDATLVIFNDELSGAQIRNIENVVGR
                     KVIDRTTLILDIFAQRALSKEGKLQVELAQLKYRLPRLYGMGGEMSRTGAGIGTRGPG
                     EQKLEIDKRHILNKAADIRRELKEVKKNRETQRVKRLKSNIPIVALVGYTNAGKSTLL
                     NELIKTHKDYEQEKEVFVKDMLFATLDVTLRKALLPNKKEFLVVDTVGFVSKLPHDLV
                     EAFKATLEEVQYADLILHVIDATNTSYELQKSTTEGVLKELGVNDKKHILVYNKVDKL
                     ELDIYPKSQEDIVYISAKQGINMDKLLNMIETALMENTYSVSLMLPYERGDIFSRIKD
                     KYNVENFEYGESGITLDVDLDEEDFNIYREYILEK"
     gene            6538..7215
                     /locus_tag="KRH23_002032"
     CDS             6538..7215
                     /locus_tag="KRH23_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HEAT repeat domain-containing protein"
                     /protein_id="HHS5225312.1"
                     /translation="MDINWENIDNLEDYFITYLLYKESKTVSQISKIRNISSTEASEQ
                     LIQAKLKIKEMQKDDFEASKDILDKFLELDKIKRLDFMDSLDDEKMVYFKRKVFKRIL
                     VEKNAEDLIVLIWATGELKDDRFLKLLHQLTNHRHSDIRRITYSAIRKIESPSSREVL
                     QKGLYDKNAQTRQYCAKALSKLGDENSLKILQQLKDKNKNFEKEYVLRAYDEAIKSLE
                     NAKNLKK"
     gene            7301..7744
                     /locus_tag="KRH23_002033"
     CDS             7301..7744
                     /locus_tag="KRH23_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HHS5225313.1"
                     /translation="MIVRRCAGGVVFYANKVLIVKNDRGEWTLPKGKILGGGLPYESA
                     VQRVKVETGIDAKMIDVAGDTMYEFFSRSRQQEVCNAIMWYVMEACNTDCVLAPEFQE
                     GGFYKVKDALEMLSHHKEQALVEVSYKKFKELKKLVSEGDDVPAN"
     gene            8049..8693
                     /locus_tag="KRH23_002034"
     CDS             8049..8693
                     /locus_tag="KRH23_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HHS5225314.1"
                     /translation="MSNYRTLHEFGTDEITIEKSVFIGYAKPIKSEEEALEFINEIKK
                     KHKDATHNVWAYTVGKNMNIQRYSDDGEPQGTAGIPTLEVIKKEDLRDVAVVVTRYFG
                     GTKLGAGGLVRAYTKGAKLGLEAGKIIYKVMYQEVKVKIDYTQLGKVQNELMNLGYFI
                     KDTVYEDNVEIVVYSRLEDVEKLSEKMIDITSGTGKIVLGEEFYLSEQNGEILI"
     gene            complement(8779..9156)
                     /locus_tag="KRH23_002035"
     CDS             complement(8779..9156)
                     /locus_tag="KRH23_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TSUP family transporter"
                     /protein_id="HHS5225315.1"
                     /translation="MLFALIGFFAGIIGGMGMGGGTILIPALVLLAGIDTKIAQSVNL
                     LSSIPMTLIALAIHIKNKNVIFKLVIPIAVFGVLGAVFGSLLANYLSSDILKKIFGIF
                     LLLVGLFEVKKGFCAKSDKKPLN"
     gene            complement(9156..9542)
                     /locus_tag="KRH23_002036"
     CDS             complement(9156..9542)
                     /locus_tag="KRH23_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HHS5225316.1"
                     /translation="MKKTDDLKQKYFDFNLKNTIIGVFTGFINGVFGSGGGTLLVPIL
                     NDIVKVEEHKSHATALSIIIFLTTASSVLYVSKGTYDVNLTIKVAVGSILGGIIGAKL
                     LNKVTGKFLRISFGIIMIIAALRMVF"
     gene            9721..10476
                     /gene="nadE"
                     /locus_tag="KRH23_002037"
     CDS             9721..10476
                     /gene="nadE"
                     /locus_tag="KRH23_002037"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008795 - NAD+ synthase activity [Evidence
                     IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(+) synthase"
                     /protein_id="HHS5225317.1"
                     /translation="MSNIKIQIDKTVEWLINKVNEANAKGLIVGVSGGIDSAVVANLI
                     KKAFPENSMGVIMSIKSNPQDREDALKVIEGCDIEYLDLDLIEPQSAILDMVVGNLKD
                     KHLYREEYLKMTDANLRARVRMSTIYTIANNLGYLVVGTDNAAEIHTGYFTKFGDGGV
                     DILPIANLTKGEVYEWAKELGVHEDLINKAPSAGLWEGQTDEDEMGTTYNMIDAVLEG
                     RLDEVPKRDQEIIERLHRLSEHKRKTPAQPPKF"
     gene            10559..11278
                     /locus_tag="KRH23_002038"
     CDS             10559..11278
                     /locus_tag="KRH23_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HHS5225318.1"
                     /translation="MGRIGNIINRKGKQDAQRAKIFTKHARAIAVAAKEGGADPEYNA
                     ALKTAIEKAKADNMPNDNIDRAIAKGAGAGAGEDYETIVYEGYGPGGVAVIVETLTDN
                     KNRTAGNVRYYFDKNGGNLGTSGCVSFMFDKKGQILVGLGDGVSEEELMDVALEAGAE
                     DFITEEDGYEIITTPEDFSSVRDELKAKGYEFISADVKMIPQTTTVLTEESHLKMMNK
                     LVDMLEEDDDVQDIYHNWEVE"
     gene            complement(11445..12449)
                     /locus_tag="KRH23_002039"
     CDS             complement(11445..12449)
                     /locus_tag="KRH23_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HHS5225319.1"
                     /translation="MATIKDIAKDCGLSSATVSYVLSGKGNERRIPLHTQELILNSAD
                     KLGYKRSTPIKHNNIKIAFYWQDEGFELASTNILQAINHIISLEHLNINIIIRPYKVG
                     HLCDDEYFFANNYYDGIVLTGINADDIEYLVKNKPKIPVVVVNREIPGFSSVSIDNEE
                     TGRIAALHAIQNGKNDIAVVFNPTSFTCMTLRGKSFLKTCKEHGIHLSDSIYYCSNKI
                     DSGYDIAQKMLAKNSLKKVIFCNHDVVALGMMNAFHESGIVIGEDIQIFAASNGPSRL
                     MARSIPPLTVIDLKMEETAERSLRMIIDTVTGRINGIQQQVIYPSIIYRQSSPAQNLL
                     "
     gene            12715..13611
                     /locus_tag="KRH23_002040"
     CDS             12715..13611
                     /locus_tag="KRH23_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA lyase"
                     /protein_id="HHS5225320.1"
                     /translation="MSKVNIFEVGPRDGFQNLKEFLETDKKLKIIDGLIASGIKQLEI
                     SSFVSPKAIPQMKDAKEVATYCVEKYPDVKLYALVPNLYGAKVAWECGIRDISYVISL
                     SETHNKKNINRTHEESIDELKKIMNTYPDMNICIGMATVFGCPFEGLPKIEDAIRFAK
                     CLWENGIREINLADTIGIADPKQVRETISALVEALPECRWQVHIHDTRNMGMVNTLVA
                     IESGITTVQSTLGGLGGCPFAPGASGNTATEDLVYMLERMGYDTGVDFVKLLELSKYQ
                     KSFVNGVYSGHHVNIKSDSCNC"
     gene            13732..14994
                     /locus_tag="KRH23_002041"
     CDS             13732..14994
                     /locus_tag="KRH23_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HHS5225321.1"
                     /translation="MDIIALLLFLGVIIIAFVRKNNAGILALAIGVIAVRIFGMDDKE
                     LYGAISNSMFTTLVGITLLFAIVNSTGALKLVAEKIVAASGKRVWLIPIAVFIAGFVV
                     AGVGPGAIPALAIIPAMAVPVAITVGYNPVMLALIGECGLMAGRMTPITPEGQIITTV
                     AEGVGIENVMPTILACQTLSTIVFSIVLFIIFKGYKLKKPINVIDSKQIEKFNIKQII
                     SLISIVVMIAFIIIFDMNVGLAAFAVSAVLIFFNIADEGECIKSIPWSTIVMVLGVGA
                     MMTIVDAAGGIDLMSNALSSLMNSKTATPIMSISAGLMSMVSSALAVVYPTMMPMCVD
                     IAKAVGGVDPLALIAAVGVGGSLAGVSPLSTGGALILAAMGSSKKDFNKEEQNKVFVQ
                     LFIMSAVGLLVIAVVSILSFNAITHLMN"
     gene            15070..16263
                     /locus_tag="KRH23_002042"
     CDS             15070..16263
                     /locus_tag="KRH23_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CaiB/BaiF CoA transferase family protein"
                     /protein_id="HHS5225322.1"
                     /translation="MKKGALSNIKVLDLTRVLAGPYCTMMLADFGADVIKIEMPRKGD
                     DTRGFGPFVNGESLYYANINRNKKGITLNLKSEEGKNIFLEMVKHADVVVENYRPGVM
                     EKLGLGYDELAKVNNQIIYGAVSGFGCYGPYSERPGYDIIAQAMGGLMSITGQEGGEP
                     TRVGNAMGDVLGGMNLTIGILTALNARKIIGKGQRVDVSLVDSVVSSLETGIQRYFDS
                     GQPELMGNRYASAYPYDSFKASDGSFVIGCGNDKLFEKLCKKVLFREDLLIDERFKTN
                     LNRCEHYKALKPEIEKWSVKHTIKEAVDLISEAGVPAAPIYNLDCVTTDEHIAKAREM
                     IVDISHPIIGNMKVNGNPVKLMTTKAKIDMPAPSLGESNEEIYNGWLGFDSDKIKDLK
                     ENGVI"
     gene            16892..17686
                     /locus_tag="KRH23_002043"
     CDS             16892..17686
                     /locus_tag="KRH23_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase-related protein"
                     /protein_id="HHS5225323.1"
                     /translation="MESVMENLNNLKVEVKDKVCVITINRPKALNALNSDTLRELSQV
                     IDVVSENEAILGVIITGEGKVFVAGADIRQMQNYKSEEGRKYAGYAQGIFDKIEALEK
                     TVIAAVNGYALGGGCELAMSCDIRIASEKAIFGQPEVNLGVIPCFGGTQRLSRLVGTG
                     IAKELIFTGRQVNAEEAKSIGLINKVVPSDLLLEESMKMMNQIVEKAPIAIRYAKVVI
                     NKGIDMDLKNALELEKDIAGLTFATRDKQEGMNAFIEKRKPVFENK"
     gene            17781..19121
                     /locus_tag="KRH23_002044"
     CDS             17781..19121
                     /locus_tag="KRH23_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HHS5225324.1"
                     /translation="MNTGVIISLVGIIIALSLLVVMVMKGINIFIIAIVCSSLVAITG
                     SLNVYDALKVDYMTGFVGFLQANFFIFLTGTLMGKIMEITGGAKSIAKMIVRWIGKDK
                     ALLSIPIACGILAYGGVSVFVVSFAVFPIALEIFKEADLPRRFIPAALTFGCSTFAMV
                     APGAPQIQNIVPASTLGTDIMAGAVNGFISCAVMFIVGSTILYKMVSKEKANGGHFIA
                     HESDIFDEAEATNSKRENGPNGVIALIPLIVSILIINVKVNGKAIVPIEVGVFIGALL
                     VYLLLNKYQDNTKIVGHVGDACKTTVVAICNTCAVVAFGSVVKSAVGFDFIVNAMTNI
                     PGPPIAGAAVGTTVIAGICGSASGGLGIAAPLLGPVFLAKGVSAAALTRTMAISSAAL
                     DSLPHNGYIVTVTNGLCKETHKDAYMPIFWVTVLTPFIGTIVAVLLFTMFPGLP"
     gene            19258..20490
                     /locus_tag="KRH23_002045"
     CDS             19258..20490
                     /locus_tag="KRH23_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CaiB/BaiF CoA transferase family protein"
                     /protein_id="HHS5225325.1"
                     /translation="MLNKPLEGVKVIDLTYFVAGPGTSKILADWGADVIKVEPSFGDP
                     GRKTGATMTMPIDDYNNPFYSTYNSNKRGLSINLKSETGIEIMDKLLSEANVFVSSYR
                     TGALKRLGLDYESLSKKHPHLIWGQINGFGDFGPAKDNAGFDTVAFWARSGAMLDIAE
                     KDTSPINPPIAFGDATTSCSLSGGICAALYQQAKTGKGQKVMASLFGQAIWNASSLLA
                     STQFSDEYPKTRKNAISPVINSYRCKDGKWIFLSILEHERYFEALCRLFGREDLIKEE
                     KFASSLESKKNATELINILDGEFAKFTQNEMVEKLTAADIAHEKIQHVNDVVTDEQAI
                     ANNYIYEHTSKNGNKTMLASTPVKFGNIEVNMTCDAPLIGEHSDEILRELGYSDSDIE
                     ALIESGIVTMNKEACEIC"
     gene            20530..21672
                     /gene="acrC"
                     /locus_tag="KRH23_002046"
     CDS             20530..21672
                     /gene="acrC"
                     /locus_tag="KRH23_002046"
                     /EC_number="1.3.1.95"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003995 - acyl-CoA dehydrogenase activity
                     [Evidence IEA];
                     GO_function: GO:0016628 - oxidoreductase activity, acting
                     on the CH-CH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_function: GO:0043958 - acryloyl-CoA reductase (NADH)
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acryloyl-CoA reductase"
                     /protein_id="HHS5225326.1"
                     /translation="MDFRLTEAQLMLQRVAKEFAENEIAPIAAETDKTGIFPRELFSK
                     MAKIGFNGIGTPVEYSGSGGADIEKVIVVTEIAKKCAASAAILSIHTIYAQAILKFGT
                     EEQKKKYLPMMAEGGCVGAFALTEPNAGSDAARAATTAIIDEETDEYVLNGTKCFISG
                     GGQAESLIIFALTDPAKGIKGMSAIIVDKGTPGFSIGKIEEKMGIHGSETAELIFDNC
                     RVPKSNLLGKEGKGFNIAMTCLDGARIGVGAQAVGIAEGALEESIKYSKERVQFGKPI
                     SALQGIQWYIADMATMVESAKLLVYYAADLKARGEKHTKEAAMAKYNASRTAREVTNL
                     ALQIHGGYGYMKDYPLERMYRDAKITEIYEGTSEIHKVVISRAVLG"
     gene            21683..22477
                     /locus_tag="KRH23_002047"
     CDS             21683..22477
                     /locus_tag="KRH23_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta"
                     /protein_id="HHS5225327.1"
                     /translation="MNIVVCLKQVPDTNEVKINKETGTLIRDGVPSIINPDDRNALEE
                     ALKMKDELGAVIKVISMGPPQAKSALKEALAMGADEAYLISDRAFGGSDTWATSTIIA
                     AAIEKVGKYDVIFCGRQAIDGDTAQVGPEVAEFLGIPQVTYAKEVKVQDDKLLVTRYT
                     ETGDYLIEAKMPVLLTAIKELNNPRYPSVKGILEAYNNGDAKITVLTLADLDVDTTQI
                     GLKGSPTNVYKSFVPVKDKHNEIIEGINKKEKAEKLIEILFDLKLV"
     gene            22491..23510
                     /locus_tag="KRH23_002048"
     CDS             22491..23510
                     /locus_tag="KRH23_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit
                     alpha/FixB family protein"
                     /protein_id="HHS5225328.1"
                     /translation="MRAKVNQGINLNDYNGVWVIGEQREGKINPVTIELIGEGRKLAD
                     QLGKELAVVIAGYEVEKEVKELLHYSVDKVYYINDPLLKDFTTDGYAISIANLIERKK
                     PEVVLVGATSIGRDIAPRIAGKVGTGLTADCTKLEIDSTDNKLLQTRPAFGGNLMATI
                     VCPKNRPQMSTVRPGVMAKAVRNESETGILEVVTPELTEKMIRTRLVEILPQEKKSVN
                     LTDARIIVSGGRGLKRAEGFELIKELADKLGAEIGASRAAVDSGWIEHSHQVGQTGTT
                     VRPELYIACGISGAIQHLAGMSDSKYIVAINKDAKAPIFSICDYGIVGDLYEIIPEMI
                     ESLNR"
     gene            23609..24985
                     /locus_tag="KRH23_002049"
     CDS             23609..24985
                     /locus_tag="KRH23_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54 interaction domain-containing protein"
                     /protein_id="HHS5225329.1"
                     /translation="MKEQWYKDIFARVLSMTDDGFIVVNTSGVIIDINDKYCDFLGKE
                     RKDIIGQNIQSIIPNTKMLDVMKNKYCEEGAIHHYSGGNTKEKSVIVSRSYVENDNGE
                     VVAGVAQVKFRLQSFDVAKKLMSEYMELQYYKEQFKDNCGFDKLIGENRDFIELKKTG
                     VKASKTNFPVLLTGETGTGKEVFARAIHNNSSRSDKPMVSINCAAIPEELLESELFGY
                     DEGAFTGAKKGGKKGKFLVANNGTIFLDEIGDMPLTMQAKLLRVLQESEIEPVGGLKT
                     IKIDVRVISATRKNLSKMVEEGLFREDLYYRLNVINIHMMELKDRQDDILLLANYILN
                     KLNVEYKELKVLSDKVKNCFINYTWPGNIRELQNVIKSAYAVSDDMVIMMCDLPSKMD
                     NISRVAQCNVDSNCSIHEMVENYEKSLIIDVLRKYNWKCSKAAEVMGIHKSLLYKKIK
                     KYEIELNN"
     gene            complement(25317..25661)
                     /locus_tag="KRH23_002050"
     CDS             complement(25317..25661)
                     /locus_tag="KRH23_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5225330.1"
                     /translation="MDQIKRLHELQQKSYLTKEEFEELKNNTYIERFELRDECDNSYI
                     YTFYTNDKCNDIKFIKSQFIVTLIKIGFLCECGGVFRQKKIVDEYDYGYNAIYKCDSC
                     GKELDKEVENYD"
     gene            26149..27159
                     /locus_tag="KRH23_002051"
     CDS             26149..27159
                     /locus_tag="KRH23_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4116 domain-containing protein"
                     /protein_id="HHS5225331.1"
                     /translation="MHEDKNDIFESIDTEDFDNKTEEECLELVRKNGLNLIYIKNQTE
                     EICLEAVRQNCNAIKCVQNQTEKICIEAVKQDWRMLEFVEEPTEEICMLAINQDGTAL
                     KYIENQTEELCLRAVEKNGAALEYVKEQTEEICIEAVRNSEFGLARVKNQTEKICMEA
                     VKHCSYNLKWVENQTEEICMEAVRQNGLDLKFVKNQTETICLRAVRQNGMALEFVKEQ
                     TVGICLKAVRQYGMALKFVKEQTEEICTEAIKQDKRALSFVKGDKEKYKALYDNNEPF
                     AKRYVRNVIEKENRALIKKGEENAKIKIAGKLYDRGMSFEDISDIVEIEISKLKVSLG
                     VF"
     gene            27295..27783
                     /locus_tag="KRH23_002052"
     CDS             27295..27783
                     /locus_tag="KRH23_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HHS5225332.1"
                     /translation="MKITVLYQTRSGNTERVAKLIEDGAKKVDGVDVKLMRLDNIDLD
                     YLNESKAVIFGTPTYLANTTWEVKKWFDEDSKKVNLAGKLGAVFATCDYICGGPDVAI
                     LTIVGHLMVKGMLVYSGGGSLGKPFIHLGHVHSIEGPELQDEKAIIFGERIATKAKEL
                     FA"
     gene            27959..29887
                     /locus_tag="KRH23_002053"
     CDS             27959..29887
                     /locus_tag="KRH23_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HHS5225333.1"
                     /translation="MVWHIEYEIFSAIIVIFLMVYFFRSKFIPTLQNKIYCALLIFSF
                     LFIISNILGSFCLNNIDKIPIFITFLLNQIYLLLLPIPAALVSFYVMAIIYQDIRYMK
                     KRLLFLSIPLIICIILSITNPFTHILFGLSKETGYIRGCGYVATFASFFFYAIYSAFL
                     SFKYRKAMHESKIWAIRGFLIVSIVAIILQAIFLQYLLTGTACACSLLLTYLSMQNRG
                     LIIDDLTGVLNRQSFIQELDLNINTEQSGFIITIALDDFKFMNETFGTKNGDIALKEV
                     GKYLIQIHDVNHVYRIGGDIFSIVVNSQLGIEPDDIIRKIEERFKKPWLVEEISFNLA
                     TSIAVVYYPENAETTEDVIVAIDFSIHEAKRSESRRVVYADASISEKIKKKHVIKNCL
                     KEALKNDGFEVYYQPIFSNSRGRFTSAEALLRLEHKELGFIPPDEFIPIAEQTGLINS
                     IGLVVFEKVCRFIASDEFEDLKLDNIAVNLSVVQCMQKNLADDLLYLMNKYNVSPTKF
                     KLEITETVAMGSFNIIKETMERLIDLGVKFALDDFGIAYSGVTNMLSLPFSVIKLDKS
                     LIWSMNEDSRHKLTVETIIALINKLNMKAVAEGVETIKCAEDLIAMECEYLQGYYFSK
                     PVPEDVFKNLLKENTFTS"
     gene            30064..30474
                     /locus_tag="KRH23_002054"
     CDS             30064..30474
                     /locus_tag="KRH23_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042802 - identical protein binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HHS5225334.1"
                     /translation="MNKKKILVPIDGTERSMHSLEFIKGIFKKDEVEVEIMNVKELVF
                     IDGISLAEEIKNSENLGRRILDKAAEIMGEYDVKVHFTFGYPGDEIIRKAKEDNVDFI
                     VMTKSTKKGLTRMIGSVTASVVKQAKCIVMIVPE"
     gene            30496..30798
                     /locus_tag="KRH23_002055"
     CDS             30496..30798
                     /locus_tag="KRH23_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIBC"
                     /protein_id="HHS5225335.1"
                     /translation="MNKKIVAVCESERSLNSLKTAANDLGFDLVYEIQENDNIKNELS
                     IYDIEDASIVLFVTSDSIESIEKIDRFIDREFYEVDPKYIIEDAKSIVSEILIDLN"
     gene            complement(31015..31707)
                     /locus_tag="KRH23_002056"
     CDS             complement(31015..31707)
                     /locus_tag="KRH23_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FadR/GntR family transcriptional regulator"
                     /protein_id="HHS5225336.1"
                     /translation="MKSLNATEKIIDYIKLNILNGTFKINSKLPSERKIADLFNISRI
                     PVRNAINILCKEGILRAVPYSSPIVEGFKKVDLFDDGEIYKNHNIQEFYVESLRARQL
                     IESEATKLAILNATSKELQKIKYTYLKSIDELDKVSHGLIEECYDADLQFHKEIILAS
                     HNPIFIKYYELIPKTVSSNQYFGFKYRNSLKDMISHHNKIMIAFDSKDSYLGYTSMYN
                     HLEDVIQLFQHD"
     gene            complement(31733..32920)
                     /locus_tag="KRH23_002057"
     CDS             complement(31733..32920)
                     /locus_tag="KRH23_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HHS5225337.1"
                     /translation="MKKISNQKLLLLSIVTFFWFSQYVYIPFQNPYLSACNVSTNMIG
                     IIIGAYGISQCLLRLPVGVFADSINKHKIFILSGIFFAGLASLIRVFSPGGNGFLIAN
                     ILSGISSSTWISYMVHYTNFFSTEHQQKATSTIILVNNLGMLIGFVMSTLFYEKLGMT
                     ALCIMSVLSSVIGTILALNIKNHNSKKIPEKISIKKYLSICKDKRLVFFSFMALIQQG
                     IQMSTTMSFTTQILKNLGSSSTLIGLSSIFYMVCAVASSGFASTKFCTKYGPKFWIPL
                     VFILVSAYCFLVPTIKNINIIFVLQVLPGISTGILLSYLTSESMKNVPKHQKSTAMGF
                     FQAIYAIGMSVFPMIVGKISEYTSIQYGYFILAIIAILASILSYTYYKKVDLTLNYDI
                     IQS"
     gene            33256..35133
                     /locus_tag="KRH23_002058"
     CDS             33256..35133
                     /locus_tag="KRH23_002058"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HHS5225338.1"
                     /translation="MDYKNIAQEILLNVGGKENVNEVTHCMTRLRFKVKSASKVNKDK
                     LSKTEGVITVVESMGQIQVVIGNKVKKVYDEVIKIVPQSNNVGKKNESQEKQGIINSI
                     LSAVAGIFTPTIPAIAGVGMIKGILSVLAMYYMNKNGVDIKETQSYIILNAMADSIFY
                     FMPIILGYTAAKVFNANKIISMVLGATLCYPTFTALMAGEESVRFLGLAVTKATYTSS
                     VIPIIIAIWALSYVEKVLEKYIPEVIKIIMVPTLSLVVMLPATLFLFGPIGIYIGNVI
                     NFSYKYIYELSPALCGAFVGGLWCVLVIFGAHRALLPIGISDVAQTGRQNLLAFAGAA
                     NFSQAGAALGVFFKTKNQGLKTISMSATITALFGITEPAIYGANLRLKKPMVCAVICG
                     AFGGAIMGMGGAYGNAFANQGVLTIPVYAEAGALGFLSYLGGCAIAFFGSAISTYLVG
                     FEDLEESSNKENSSIKVETKDGVIDITSPVEGECIELSEVKDDVFASKAMGEGIAVLP
                     TKGVITAPTDCEVASLFPTLHAIGLKLDNGAEMLIHVGINTVELNGKYFTKHVNQGDL
                     VKKGDKLISFDIDKIKKAGYDVTTPVIVNNTFDFGQVVSCKSSYVSTNDNIISLVLAG
                     N"
     gene            35355..36761
                     /locus_tag="KRH23_002059"
     CDS             35355..36761
                     /locus_tag="KRH23_002059"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HHS5225339.1"
                     /translation="MNTGFPKDFLWGASSSAFQVEGAWDKDNKGKTVADYNSFKKSHL
                     QADTKVASDFYHNYEEDIELMKELGMKTYRFSISWARIIPDGEGEINQKGLDFYNKII
                     DKLIECDIEPFVTLYHFDLPFKLVEKYNGWESRETVYAFERFAKICFKHFGDRVKYWQ
                     PHNEQNLIVRVEERINIYDETDSWKIDKMRAQMDYNLCLAHALAVNACHEMIKESKIG
                     AAVSSSVTYPLTSKPEDVYAARMNDNFKVYYMLDMHHYGEYPGYYMKYLEKRNIVPHM
                     EDGDKEILKKAKMDFIAVNYYRTNCAEALPEDSQHPFGLREGTVDFSMYGLFKMSMNP
                     NLEASEYGAAIDPSGLRVALNEYWQRYHLPVIITENGLGAKDILEDGKIHDDYRIDYL
                     RSHINACKLAIEDGVEMIGYCPWSFTDLLSSSQGFNKRYGLVYINRTDHEVLDLKRIK
                     KDSFYWYKEVIENNGIVK"
     gene            36789..37637
                     /locus_tag="KRH23_002060"
     CDS             36789..37637
                     /locus_tag="KRH23_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HHS5225340.1"
                     /translation="MYITKVLNNSLLLAKDDNDEEIILMGKGIGHNYKAGSELNKKDI
                     EKIFVLHDENIKKSIIQLATEIDAEYFGIAQMIIAYGIEKYNLKLMNHIYLALTDHIA
                     FAVRRFKEGIMIENHYLFEIKEFNPKEYDIGKYAITVFKEVLGLDLPEEEIGNIAGHF
                     INAQQDNPYSDRNKRSAKIVNAILQIVHYHFSIVYNKESFYYRRFVMHLKAFSQRFLA
                     NEPSREKIDFIYEQVQKNCKEEYECVKKVGAYMYKEYSRELPRQEELYLMIHIHKILG
                     ELCENS"
     gene            38309..39001
                     /locus_tag="KRH23_002061"
     CDS             38309..39001
                     /locus_tag="KRH23_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HHS5225341.1"
                     /translation="MNKVLIIDDDKDLCILLKKSISIEQIEANYCHSGRDGLVELSKQ
                     DYQLVVLDVMMPGMDGFETMEQIRKYSSIPILMLTSKSDNYSKVHGLRAGADDYLTKP
                     FEITEFTARVLSLIRRYTRFNPKNEEPQQLSFKGLLIDLDQHTVTTNGEPMLLPPKEF
                     GVLLYCARHQGKILTKQQIYEAVWGEPYVYDDSNIMAIISRLRKKIELDPSSPIYLQT
                     IKGIGYQFNTEV"
     gene            38998..39933
                     /locus_tag="KRH23_002062"
     CDS             38998..39933
                     /locus_tag="KRH23_002062"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HHS5225342.1"
                     /translation="MKMDEQTIILFLLLLSIGLLFLSIFAFSKLGHIYKRLKDIEEIL
                     ADVRIGDENRKILIKPCDVMAPLVYQLNEIVYDYENKLLSLKKSDKASRQLMTSLSHD
                     VRTPLTTLIGYLDAVHSGIVIEQEREEYLEIARRRAYDLKDYIDVLFDWFRLNSDEFT
                     LSIESVEIAELSRNILKDWIPIFHEKKLNFEIDIPENRLMVNLDPDGYSRVVNNLVQN
                     VLAHSKARQIKITMSEDSRMVLLRVEDDGVGIARENLPHIFERLYKCDKGRSEKGSGL
                     GLSIVSQMVERMGGQISVESEIGKYTIFTVSLPLI"
     gene            40081..41004
                     /locus_tag="KRH23_002063"
     CDS             40081..41004
                     /locus_tag="KRH23_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019639192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHS5225343.1"
                     /translation="MNNLIIETKNLTKQYGAQKSVSNLNIHVQKGRIYGLLGRNGAGK
                     TTTMKMLLGLTKPTTGEIKIFGQDIHNNEKKLLPRIGCLIESPGFYPNLTGTENLKIF
                     ARLRGIPKKNAVESALDVVGLPNNDKKLFSQYSLGMKQRLAIALAIMHDPQLLILDEP
                     INGLDPIGIAEVRTFIRDLCTERGKTILISSHILSEIALLADDIGIIDHGILLEEESL
                     AQLEEKNSKYIHFAVSDAAQAARLLETQLNLKNFKVADNYNIMLYDTDVSVAEINRAF
                     ILNNIEVSESHLCEDTLEDYFKKVTGGEGIA"
     gene            40988..41758
                     /locus_tag="KRH23_002064"
     CDS             40988..41758
                     /locus_tag="KRH23_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHS5225344.1"
                     /translation="MKELLDIISCEFSKLKRLKFILISILGACLFPIPATILIAKDNL
                     PFEQLFKLVVNFGYFLLLPIVLSIVASQLFFIERDNDVLKNLATVPVPKGKLALAKLA
                     VLLFISLFYSVAGLGATIIGGFIVGIVEGVAVKLGMSIAFGIMFFVTVLPVVVLIVYF
                     NRSYIFSIILSFVYAIFNFSISLNIINFEPNNPLLSVLPAPVIMRWWMAFWGDPTGEY
                     TVLRQPYLLSTPACVGILCLITIIAVLLICMIYKKQEN"
     gene            41768..42550
                     /locus_tag="KRH23_002065"
     CDS             41768..42550
                     /locus_tag="KRH23_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHS5225345.1"
                     /translation="MLDIITTEFQKIKRYNILWIGVVAVLFSALLAVFQVVSSHGSDP
                     LTYESFANGVIWNNFSLSFPFGITLIGGYLINREYTDQTLKNILTVPISLRKLLVGKL
                     IAVGGITVLLSLFSFLCTFILGLLFCNINISVILVVKSLVQILSVNLYCYVAVLPIIA
                     YFGRKQNAFLTGVGIAFVYGFCGVFVAGRNLTDFYPITAGLGLVGYNNGAGTVYQPLI
                     GAMTLIVILILTTILLVFTPNYDKVMTISKKKGIKHKKYSHK"
     gene            42927..43463
                     /gene="rbr"
                     /locus_tag="KRH23_002066"
     CDS             42927..43463
                     /gene="rbr"
                     /locus_tag="KRH23_002066"
                     /EC_number="1.11.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0016692 - NADH peroxidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rubrerythrin"
                     /protein_id="HHS5225346.1"
                     /translation="MNLKGTKTEKNLMAGFAGESEARNKYTYYASKARKEGYNQIAAI
                     FEETANNEKEHAKLWFKLLHDGMPSTEENLKDAAAGENYEWTDMYAKFAKEAREEGFD
                     KIAYLFEAVGKIEKEHEERYLKLLENLNEGKIFKRDEEVVWQCQNCGHVYVGTEAPEK
                     CPVCDHPKAYFNIKAENY"
     gene            43495..43884
                     /locus_tag="KRH23_002067"
     CDS             43495..43884
                     /locus_tag="KRH23_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fur family transcriptional regulator"
                     /protein_id="HHS5225347.1"
                     /translation="MKFSKQRELILNEILNNPVHPTADYLYENLKKDNPSLSLGTVYR
                     NLAQLTEHGFIRKVSIPGYPDRFDGRIDNHYHIICEVCGEVYDLESEVLNNLQELISE
                     ETDIKITSYNISFKGICNNCKRCSQVG"
     gene            43921..44307
                     /locus_tag="KRH23_002068"
     CDS             43921..44307
                     /locus_tag="KRH23_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="desulfoferrodoxin family protein"
                     /protein_id="HHS5225348.1"
                     /translation="MCSEQKFFICETCGNLVGMIQSGGVPIFCCGKPMKELVPNTTDA
                     AVEKHVPVIEVDGNNVTVKVSSTTHPMTKEHHIAWVYLMTEQGGQRKCLAVDGEPVVK
                     FALNDDDKVISAYAYCNLHGLWKAEL"
     gene            44434..45876
                     /locus_tag="KRH23_002069"
     CDS             44434..45876
                     /locus_tag="KRH23_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015930 - glutamate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0016638 - oxidoreductase activity, acting
                     on the CH-NH2 group of donors [Evidence IEA];
                     GO_process: GO:0006537 - glutamate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate synthase-related protein"
                     /protein_id="HHS5225349.1"
                     /translation="MSIYKCSVCGYIYDESKNDKTWDELSEDWECPVCTKGRSYFGKI
                     STVYYEEDEKIAEDIVEDESKLNTEKEGDLNYLSTYLRRDDEVEKHMDIIHEMAVTGK
                     SIIEPMRTKLPVISWDDILIMGAQLNPLPLNEHDEVNTTTIIGKKAKKPMIIENPVYI
                     SHMSFGALSKELKIALAKGAAQNKTAMCSGEGGILPEEKEASYKYIFEYVPNKYSVNE
                     ENLKNSDAIEIKIGQGTKPGMGGHLPGEKVTEEIAKVRNKPVGQDVISPSCFEEIQSK
                     EDLKKLVDELREVSEGRPIGVKISAGHIEKDMEFIAYAKPDFVTIDGRGGATGASPKL
                     LKDATSIPTIFALYRARKYIDTHGLDIDLVITGGLRISTDFAKAIAMGADAVAIASSA
                     LMAAACQQYRICGSGKCPVGVATQDEELRKRLHIENSANRVANFLNVSLEELKTFARI
                     SGHKDIHDLSVDDLYTVNSEISNYTNIQHV"
     gene            46166..46981
                     /locus_tag="KRH23_002070"
     CDS             46166..46981
                     /locus_tag="KRH23_002070"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HHS5225350.1"
                     /translation="MERLKIQVLVDNNTYIDRYFVGEPAVSYYIEIDGNRILFDSGYS
                     DVFISNAEKLNIDLGNLTHVVFSHGHNDHTRGIQFLENRYDLSTVELISHPNCFIPRK
                     HGEKSIGAPFSAEEIKNIFMYNPKDKPFNLSKNCVFLGEIPSINDFEKRSKIGKCKIG
                     DLWEDDYVLDDSAIVCKTDKGIFIVTGCSHSGICNIVEYAKKVCGDDRVIGILGGFHL
                     FELNNRLDSTIQYLDKEEIRMLYPCHCVSFKVKAKMNEILNINEVGVGLTISI"
BASE COUNT        17583 a         5523 c         8711 g        15227 t
ORIGIN      
        1 taggttaaat aaaagtacct ttagaccaaa tatattatta ataacttaat aacatcttaa
       61 aacctattta tttatattat ttacaacatc catttaataa atacaccata acctacagct
      121 gggtcgtttt caattgcatg tgacactgct ccgattattt tattatcttg aactattgga
      181 gtaccactca taccttgtac aataccacca gtttgagcta aaagcttttt atctgtaatt
      241 ttaattttaa aacttttact ttctggatgt ttttggtttt ctatatctat aatttcaata
      301 ttatattttt tacacttatt aaagttatct tgtaaaatta tttgagcttt tcctaattta
      361 acttcatcta aagatgctac tttatatttt tttaacttgg aaatatcaaa gttattaatt
      421 tgacctctta ttccaaaatc agtattttct gtaaagctac caataatatt ttctcgtttt
      481 gcatttatac atccaacact acctttataa gatttttcta tattaaggtg cttagttgta
      541 gaaattgaac ctgttttaat aggtattttt cttgcattac caacacttat tggatgacct
      601 acagctccaa actctgatgt atctggattg atatacgtta aagtagcaaa tccagaaagt
      661 aaattgttaa aactaatttt ttctaatatg tgtttggtag ttttcattgt tataagttgt
      721 ccacctctat ttaataaaat agatacttgt ttttcttctg gtaaagcatt taaggtattg
      781 gcaaagtcac tatatccatc aacttcagca ttatttacct ttactatagc atcacccaat
      841 ctaaatggag atgcttctcc aggatttcta actatgatat tttttaattc tgcgtcaatt
      901 tgaagtacgt ttccaattgg tattaaatat tcaggttcat ttttttgtaa attttgtgca
      961 taaattaaat tatttgagaa aaaatataat aaaaataaaa atgttaaaac aattgtaaat
     1021 tttgacttag ctaagttggt ttttttactt aaagtattat ttttaaaatg aaaattttta
     1081 agttgcataa gacacctctt tcttattaaa ttattttaat aatagaattg aagttttctt
     1141 gttgcttcta tattatgttg tgcaagaatc atgttttgat gcttggaaaa ctagctcaat
     1201 aacaccttag ttttcataaa aataaataaa ataaatagtg tatatgataa aataaataca
     1261 tattcatata aataaaaata aacaataact gtctagcata agaaaggagc aaaaaatgaa
     1321 aaaatataga ttgttagtta cttgtataat tgccatggga atcataatta taggaacatc
     1381 aaatccagtt agcaattttt acaagactac aaatttgatt agttcaggaa atatcacaaa
     1441 tgaaaaagca gataaagatg aaaattcaaa caaaaataat aaagataaaa atgaagacaa
     1501 atctaattct aaaagtaata aagataagtc atcagaggac aaatcgtcag ataataaaaa
     1561 tgaaattcaa aaaaataaaa aacttttaat ttgtatagac ccagggcatc aaggaaaagg
     1621 agatagcaat ttagaaccag tagctccagg ttcttcctct aaaaaagcaa gagtatcttc
     1681 aggaacagag ggtattgcta caaaaaagcc agaatatgtt ttaaacttag aagcatctct
     1741 tgttttaaag agtatattag aatctaaagg ttataatgta ataatgacta gagagacaca
     1801 tgatgtaaat ataagtaatt cagaaagagc aatacttgct aatgacaaaa aagcagatat
     1861 ggttgtaaga atacatgcag atagtttaaa taattcttca aaaactggag catctatatt
     1921 gattcctgaa aaagatggaa aatatacagc tcctatatat gaagaaagta ataaatgtgc
     1981 tgaatttatc aaacagaata tggaacaatc aggtatacaa atcaatggaa tcgttcaaag
     2041 aggcgatttg actggattca actggtcaaa agtaccagct gtattagtag aaatgggatt
     2101 tatgagtaac tataatgaag accaaatgat gtcaaatcca gactaccaaa gaaaaatgat
     2161 gcagtgtata gctgatggat tggatgcgta ttttaaataa gatatgaata gagaaaaagt
     2221 taggttggta ttattttcct aatttttatc tctatttttt attgtacata acacaaagaa
     2281 gaagtttatt ttaggttaaa ttgtcgtaaa tataactaaa aatattggga atacttgatt
     2341 taagtttaaa aagaatatat tatagtatag aatgtgtaaa atttttttga gaggtgttga
     2401 aatgctagta gtagaaaatg tgagtcatgg atttggtgcg agaacaatat tagaaaatgt
     2461 atcctttaga cttagaaaag gtgaacatat tgcactagtt ggtgctaatg gagaaggaaa
     2521 atcgagtttt ttaaatataa taacaaagaa gcttatgcca gatgctggaa atataaaatg
     2581 gtcttcaaga gctacagtag gttacttaga ccaacatacg gtattaagca agggaaaaac
     2641 tataagagaa gtgcttagag aggcttttaa gcatatgttt gacttagagc aagaaatgat
     2701 tgctatgtat gacaaaatgg gagaagctag tgatgatgaa atgagtaagc ttcttgaaga
     2761 aacagcagag atacaaacta tacttgaaaa tagtggtttt tatatgatag atgcaaagat
     2821 acaagaagtt gcaaatggtc ttggtcttgg agaaattggt cttgataaag atgtaactga
     2881 cttaagtgga gggcaaagaa caaaagtact tcttactaaa cttctacttg aaaatccaac
     2941 tattcttata ttggatgagc ctacaaacta tttagacgaa gagcatataa catggcttac
     3001 taagtacctt caagagtatg agaatagttt tgtcttagtt tctcatgata ttgaatttat
     3061 aaataataca tgtaatgtaa tatatcatat ggaaaatgga gagttaaata gatataaagg
     3121 aaattatgat gaatttgtaa gacttaatga tataaagaaa cgtcaagaag aacaagctta
     3181 tgataaacaa gttgaagaaa gaaaaagact agaggatttt gtagctagaa ataaagctag
     3241 agtagcaact agaggaatgg ctaacagtag gcaaaagcaa cttgataaga tggaaatatt
     3301 agaaagacca aaagaaaaaa taaaacctac ttttgctttt aaagatgcta gagcagctag
     3361 taaaataatt tttgaaacag aaaatttagt tttagggtat gatgaagcat tgacaaaacc
     3421 acttaatttc catttagaaa gaggaaaaaa gattgcctta aaaggaatga atggtattgg
     3481 aaaatctact ctattaaaaa ctttacttgg aataataaaa ccatttgaag gaaatgttaa
     3541 attaggtgac tatttggaag ttggatattt tgaacaagag agttcaagag aaaatagtaa
     3601 tacacctatg gatgaagttt ggagtgaatt tccagggctt acaaactttg aagttagaca
     3661 ggctcttgca aaatgtggac ttacaaatga acatataacg agtcaaatga gagtattaag
     3721 tggtggagaa gctgctaagg ttagactttg caaagtaatg ttaaaaaata taaatttctt
     3781 agtattagat gagcctacaa atcatttaga tgttgaggca aaagatgaat tgaagaaggc
     3841 tatcaaagag tttaagggaa cagttctttt agtatgtcat gagccagaat tttattcaga
     3901 aattgttgat gatgtatgga atatagaaga ttttacaact aaaatcgtgt agtgatttaa
     3961 cttattgctg gggggatttc atgagaaagt ttctaaatgt acttttttca gtttgtatta
     4021 gtattgttat aatagtaggt gttattaatt ttactgttgg atttaaacaa ctttattatt
     4081 ttgacattga ttacttaaat atatcagagt tatctggttt atctaaagat gatataaaat
     4141 tgaactacga ttatctaatt gattataact taaataagaa tgtgtctgag ttcaaattac
     4201 caacattaaa atcttctcca caagggaaga tacattttga agaagtcagg aatatatttc
     4261 aaaatataaa taaattagct aaagtattat tggtagtttc tttagtagga attatattga
     4321 gtgtaaaaaa taaaaatata aaaatcttga aaactacatc aataacactt ataattatgc
     4381 cattattatt aacagttcca attttattaa attttgaaaa gtcatttatt atttttcata
     4441 aattattatt tagaaatgat tattggatat ttaatcccga tttagaccca gttataaata
     4501 tattgccaga ggaatttttt tttcactctg gaatgatgat tttaatatta attttgttag
     4561 taagtatatt actgtttgta atgtataaat tatgtaaatc tttatcaaaa aaaatatttc
     4621 aatgttaaat agagggatat ttttatttcc aaaataagat aataaaaaag gattagatta
     4681 aaagttatac aataaaaata gctgtgcaat aatatttaga ctatgaaagt agttaaaaaa
     4741 tatttatgca cagctattta taatagaatt tactttttac tagtgatttt aactaaatct
     4801 tgaaatttac tcataatgta attgtaatta tcttttttat gaggtaatat acaactactg
     4861 caatctttga tacctttatc tgtatactta aagtttccac cacagttttc tcctaaagca
     4921 tacaaaggac aatagcaaaa tagacagtta aactcttctg gtttattagt tttatgacaa
     4981 gggaaaaatt cgcaatcttt gtgattaaaa aacttataat tttcgcccat attttcctcc
     5041 taattaaata aaatttaaat tttttatact atataagatt ttggtgataa tataattata
     5101 ctaaataatt ttatgaatag tcgataatat agtattatta atcatagtat taatggtata
     5161 attagtcaac agaaaaataa tgtaaaaata atgtaagtgt attttgtaat tagaatatgt
     5221 tttataacaa aaaatgaggt gattaagtga aagaaattca agaaaaagca cttcttgtag
     5281 gtctgaattt gactacaata gtgaaaaaaa atgatgatat agacactaat gaatctatgg
     5341 aagaattaaa agaactaaca aaagctgctg gggcagaagt tgtaggtagc ttaattcaaa
     5401 ataaacactc tgtagatgca gcttattata taggaaaagg taaagtagaa gaaataagag
     5461 cctatagtga ctctttagat gctactttag taatttttaa tgatgaatta tctggtgctc
     5521 aaatcagaaa tatagagaat gttgttggaa gaaaagtaat agatagaact actttaattt
     5581 tagatatatt tgctcaaagg gcacttagca aagaaggtaa attacaagtt gaattagcac
     5641 aattaaaata tagattgcca cgactttatg gaatgggtgg tgagatgagt agaacaggtg
     5701 cagggattgg tactagaggt cctggagaac aaaaactaga aatagataag agacatatac
     5761 ttaataaagc agcagatata agacgtgaac ttaaagaagt aaaaaagaat agagagacac
     5821 agagagttaa gcgtttaaag tcaaatatac cgattgtagc acttgttggg tatacaaatg
     5881 caggaaaatc taccctgttg aacgaattaa taaagacaca caaggattat gaacaagaaa
     5941 aagaagtttt tgtaaaagat atgctttttg caactttaga tgtaactttg agaaaggctc
     6001 ttttgccgaa taaaaaagaa tttttagtag tagatactgt tggatttgta agtaaacttc
     6061 cccatgattt agtagaagcg tttaaggcaa cattggaaga agtacagtat gcagatttaa
     6121 tcttacatgt aattgatgca acaaatacta gttatgaatt gcaaaaaagt acgactgaag
     6181 gtgtattaaa agaacttggt gtaaatgata aaaaacatat acttgtatat aataaagtgg
     6241 acaagctaga attggatata tatcctaaaa gtcaagaaga tattgtgtat atttctgcaa
     6301 aacaaggcat aaatatggat aagttattaa atatgataga aactgcttta atggaaaata
     6361 cttattcagt aagtttgatg ttaccttatg agagaggtga tatatttagt agaataaaag
     6421 ataaatataa tgtggagaat tttgagtatg gggaaagtgg tataacgcta gatgtagatt
     6481 tagatgaaga agattttaat atctatagag agtacatact agaaaaatag gttgaatatg
     6541 gatataaact gggaaaatat agataatctt gaagattatt ttataaccta tcttctttat
     6601 aaagaatcta aaacagtatc tcaaattagt aaaattagaa atatttcaag tactgaagca
     6661 agtgagcaac ttatacaagc aaagttaaaa ataaaggaaa tgcaaaaaga tgattttgag
     6721 gcatctaagg atattttgga taaatttcta gaactagata aaattaagag acttgatttt
     6781 atggatagct tagatgacga aaaaatggta tactttaaga gaaaggtttt caaaagaatc
     6841 cttgtagaaa aaaatgctga agatttaatt gttttaattt gggcgacagg tgagctaaaa
     6901 gatgataggt ttttgaaatt gcttcatcag ctcacaaacc acagacactc agatattaga
     6961 agaataactt attcagcaat cagaaagatt gaatcaccaa gtagtagaga agtactgcaa
     7021 aaaggtctct acgacaaaaa tgcacagact aggcagtact gtgcaaaagc tctttcaaaa
     7081 ttgggagatg aaaacagttt aaagatttta cagcagttga aagacaagaa taagaatttt
     7141 gaaaaagaat atgtgcttag agcttatgac gaagccatta agtcattgga aaatgcaaaa
     7201 aatttgaaaa agtaattttt tattaaagca atttgtttac ttaatgatgt atttctaaag
     7261 tttaacaagg taataaataa attaatggga ggggtttcaa atgatagtaa gacgttgtgc
     7321 aggtggagta gtgttttatg ctaataaagt acttattgta aaaaatgata ggggtgaatg
     7381 gacacttcca aaaggaaaga tactaggagg gggacttcca tatgagagtg ctgttcaaag
     7441 agttaaagta gaaactggca tagatgctaa aatgatagat gtggctggcg atactatgta
     7501 tgaatttttc tcaagaagta gacaacaaga agtttgtaat gcaataatgt ggtatgttat
     7561 ggaagcttgt aacactgatt gtgtacttgc tcctgaattt caagaaggtg gattttataa
     7621 agtaaaggat gctttagaaa tgttatcaca tcataaagag caagctttag tagaagtatc
     7681 ttataaaaag tttaaggaat taaagaaatt agtttcagag ggcgatgatg ttccagcaaa
     7741 ttaattgtga atttagagga ttctgaggaa gggatagccc cttccttttt taattgaagc
     7801 agttttaagc gtaaattata tagtctcttt aaactatgat ttatcaattt agagatttag
     7861 tagtttatat ttaaaatcag taagatatat ttaaaataaa aattaaaaag tatacaattt
     7921 tattatataa ttgtcttatg atgttgatta aagaagtatt aaaagtccat ttatttttaa
     7981 atagaataat tttataaata tatatttgat gtgtatatta gaaaatgatt aaaataggag
     8041 gaaatacaat gagcaattac aggacattac atgaatttgg aacggatgaa ataacgattg
     8101 aaaagtctgt ttttattgga tatgctaagc ctataaagag tgaagaagaa gcattagagt
     8161 ttataaatga aataaagaaa aagcataaag atgcaactca caatgtgtgg gcttatactg
     8221 taggtaaaaa tatgaatata caaagatata gtgatgatgg agaaccacaa ggaacagctg
     8281 ggatacctac attagaggtt ataaaaaaag aagatttgag agatgtagcg gttgttgtta
     8341 ctaggtattt tggaggaaca aaattaggtg caggtggtct agttagagct tatacaaaag
     8401 gtgctaaact gggacttgaa gcaggtaaga taatttataa ggtaatgtat caagaagtta
     8461 aggttaagat agattatact caacttggaa aagtgcaaaa tgagttaatg aatttggggt
     8521 attttataaa agatactgta tatgaggata atgttgaaat agtagtatat tcaagattag
     8581 aagatgtcga gaaattatca gaaaaaatga ttgatataac aagtggaaca ggaaaaatag
     8641 ttttaggaga ggaattttat ttgtctgaac aaaatggaga aattttaata taatctaaaa
     8701 ggttattaga atagttaata cctcaaatag ccaattagta tttttaagtg aaaagccatt
     8761 aaattgattt aatctaaatc aatttaatgg ctttttatcg gattttgcac agaatccttt
     8821 ttttacttca aataaaccga ctaaaagtaa aaatatccca aatatttttt ttaatatatc
     8881 tgaagacaga taattagcta atagtgaacc aaatacagct cctaaaaccc caaacacagc
     8941 tataggtata accaatttaa aaattacatt tttatttttt atatgtatag caagtgctat
     9001 aagtgtcata gggatagatg aaagtaaatt tacgctttgt gctattttag tgtctatgcc
     9061 agcaagtaaa acgagtgcag gtataaggat tgttcctcca cccattccca ttcctccaat
     9121 aattcctgca aaaaatccaa ttagagcaaa taacattaaa acaccatcct taatgctgca
     9181 attatcataa ttattccaaa agaaattcta agaaactttc cagtaacctt atttagtaat
     9241 ttagctccta taataccacc aagaatactt ccaactgcaa ctttaattgt taagttaaca
     9301 tcataagtac ctttagatac atataaaaca gaacttgctg tcgttaagaa tattattata
     9361 gaaagagcag ttgcatgaga tttatgttct tctaccttaa cgatgtcatt taatattgga
     9421 actaaaagag tacctcctcc agaaccaaaa actccattta taaatcctgt aaaaactcca
     9481 attatcgtat tttttaagtt aaaatcaaag tatttttgct ttaaatcatc agtttttttc
     9541 ataaaaatca ccttctgaaa tagttttacc aaaataggca aattatattt atataaaata
     9601 agattaaata taatctttca tgtttgttta attttgcata aaaaaaaaca tattaaaaca
     9661 acatattaat atatggtata atatattaaa acaaagtagc aaatttgaga ggagataaca
     9721 atgtcaaata taaaaataca aatagacaaa actgtagaat ggcttataaa taaggttaat
     9781 gaggcaaatg caaaaggatt aattgttggt gtatctggag gaattgattc ggcagtagtt
     9841 gctaatttaa ttaaaaaggc atttccagaa aactctatgg gagttataat gagcataaaa
     9901 agtaatcctc aagatagaga agatgcactt aaggttatag agggatgtga tatagaatac
     9961 cttgatttag accttataga accacaaagt gctatattag acatggtagt aggaaattta
    10021 aaagataaac atttatatag agaagaatat ttaaagatga cagatgcaaa cttaagagca
    10081 agagtaagaa tgagtacaat ttatacaatt gctaacaatc taggatatct ggttgttggt
    10141 acagacaatg ctgcagaaat acacacagga tattttacta aatttggtga tggtggagtt
    10201 gatattttac ctattgcaaa tttaactaaa ggagaggtgt atgaatgggc aaaagagctt
    10261 ggtgttcatg aagatttaat aaacaaagct ccttcagcag gtctttggga aggtcaaaca
    10321 gatgaagatg aaatgggaac tacttacaat atgatagatg ctgtgttaga aggtagattg
    10381 gatgaagttc ctaaaagaga ccaagagata attgaaagac ttcatagatt aagtgaacac
    10441 aagagaaaaa cgcctgcaca acctcctaag ttctaattta ctatttataa gatttgtgat
    10501 aaaatttaca agtgatgaaa attagaataa ttaattgtac gtattaagga gtggaaatat
    10561 gggacgtata ggtaatataa ttaatagaaa aggtaaacaa gatgctcaaa gagcaaagat
    10621 atttactaaa catgctagag caatagcagt tgcagctaaa gaaggtggag cagacccaga
    10681 gtacaatgca gcgttaaaaa cagctataga aaaagctaag gcagataata tgccaaatga
    10741 taatatagat agagctatcg ctaaaggtgc tggagcaggt gctggagaag actatgaaac
    10801 tatagtttat gaaggatatg gacctggtgg agttgctgtt atagtagaaa ctttaactga
    10861 caacaaaaac agaactgctg gtaacgtaag atactatttt gacaaaaacg gaggaaactt
    10921 aggaactagt ggatgtgtgt cttttatgtt tgataaaaaa ggacaaatat tagttggttt
    10981 aggagatgga gtttcagaag aagaattgat ggatgttgca ttagaagcag gagctgaaga
    11041 tttcataaca gaagaagatg gttatgaaat aataactaca ccagaagatt tttctagtgt
    11101 tcgtgatgag ttaaaagcta aaggatatga gtttatatct gctgatgtga agatgatacc
    11161 tcaaactaca actgtattga ctgaagaatc tcatttaaaa atgatgaata aattagttga
    11221 tatgcttgaa gaagatgatg atgttcaaga tatatatcat aactgggaag tagaataaat
    11281 agtataagca tattgaaatt tataagtatt taatcaattt taacatgtga taaattttat
    11341 agaataagaa acactaaaat agacatacgc acctctaacc tatatttgca taataatatg
    11401 taagcatagg taaggggtgt ttttatattt atagattaag aaatttaaag taaattttga
    11461 gctggactcg attgtctata aataattgat gggtatataa cttgttgctg aataccattt
    11521 atacgcccag ttactgtatc aataatcatc ctaagactac gttctgctgt ctcttccatt
    11581 tttaaatcta taactgtcaa aggaggaata cttcttgcca ttagtcgtga aggtccatta
    11641 cttgctgcaa atatttgaat atcctctcca attacaattc ccgattcatg aaatgcattc
    11701 atcataccaa gagctaccac atcatgatta caaaaaatta ctttttttag tgaatttttt
    11761 gcaagcattt tttgagcaat atcatatcca ctatctattt tattagaaca ataatatata
    11821 gaatctgata gatgtattcc atgttcttta catgttttta aaaaagattt accccttaaa
    11881 gtcatacatg taaaggaagt tgggttgaat acaacagcaa tatcattttt accattttga
    11941 atagcatgta aagctgctat acgaccagtt tcctcattat caatagatac acttgaaaaa
    12001 ccaggtattt cacgatttac aacaactaca ggaattttag gtttattttt tactagatat
    12061 tctatatcat cagcattgat acctgttaaa acaattccat cataataatt atttgcaaaa
    12121 aagtattcat catcacatag atgaccaact ttgtaaggtc gtatgatgat atttatgttt
    12181 aaatgttcta aagaaattat gtggtttatt gcttgaagta tattggttga tgccaactca
    12241 aatccctcat cctgccaata aaaagctatt ttaatattat tatgtttaat aggagtagag
    12301 cgtttatatc caagcttatc agctgaattt aatataagct cttgtgtatg tagcggaatc
    12361 ctgcgttcat ttcctttacc acttaagacg tacgagacag ttgctgaaga aagaccacag
    12421 tcttttgcaa tatctttgat tgttgccatg ataaaatcct ccttaaatag ttgcttaaat
    12481 ttgcttatac caataatctt aacatatatt caactaaaga acaatattct acaaggtgca
    12541 tattttacag gattagaata aataaattta aaaaaacttc ttacttatgt tgacataatt
    12601 tagtttatag gattataata tgcttaaata agcttatgat taacttaaat taagcaaagt
    12661 taagcaggaa catgcaatgc tagcttgcaa tgtgactgta aagggggaaa aggtatgagt
    12721 aaggtaaata tatttgaagt tggtcctaga gatggatttc aaaacctgaa agagttttta
    12781 gaaactgata aaaagcttaa gattattgat ggtcttattg cttcagggat taaacaactt
    12841 gaaattagtt catttgtaag cccaaaagca atacctcaga tgaaagatgc aaaagaagta
    12901 gcaacttatt gtgtagaaaa atatcctgat gtgaaacttt atgcattagt tccaaattta
    12961 tacggtgcta aagttgcatg ggagtgtggt ataagagata tatcctatgt tatatctttg
    13021 agtgaaactc ataataaaaa aaatataaat cgtacccatg aagagtctat tgatgaactt
    13081 aaaaaaataa tgaatactta tccagacatg aatatatgta ttggaatggc tactgtattt
    13141 ggatgtcctt ttgaaggttt accaaaaatt gaagatgcca taagatttgc taaatgcctt
    13201 tgggaaaacg gtatcaggga gataaatcta gcagatacaa tagggattgc tgaccctaag
    13261 caagtaagag aaactattag tgcattagtt gaagctttac cagagtgcag atggcaggta
    13321 catattcatg atactagaaa tatgggaatg gttaatactc ttgtggctat tgaatctgga
    13381 attactactg ttcagtctac acttggagga ttaggaggat gcccatttgc tcctggagca
    13441 tctggcaata ctgcaactga agatttagta tatatgcttg aacgtatggg gtatgataca
    13501 ggagttgatt ttgttaaact tcttgaatta tcaaagtatc agaagagttt tgtaaatgga
    13561 gtatatagtg gtcatcatgt aaatataaag tctgatagtt gtaattgtta gttctattga
    13621 ttaatcgatt aaaaaaatat gctgattggt aaaatagatt tattgataaa aaatataaat
    13681 tataaaatac attatctaat aaaacaaata aaaaaattga gggggattag tatggatatt
    13741 atagctttac ttttattttt aggagttatt attattgcat ttgtacgtaa gaataatgca
    13801 ggtattttgg ctctagctat tggtgtcata gctgttagaa tttttggaat ggatgataaa
    13861 gaactttatg gagctataag caactcaatg tttactacac ttgttggtat aacactactc
    13921 tttgcaatag tgaactcaac aggagcatta aagcttgttg cagaaaaaat tgtagctgct
    13981 tctggtaaac gtgtttggct tatacctata gcagttttta tagcaggatt tgttgttgct
    14041 ggtgttggac ctggggcaat tccagcactt gcaattatcc cagcaatggc tgttcctgta
    14101 gccataacag ttggttataa ccctgtaatg cttgcactta taggtgaatg tggattaatg
    14161 gcaggtcgta tgactcctat tactccagaa ggtcaaatta taacaaccgt tgcagaaggg
    14221 gttggaattg aaaatgttat gcctactatc ttagcctgtc aaactctttc tacaattgta
    14281 ttttcaatag tattgtttat aattttcaaa ggatataaac ttaaaaaacc tataaatgtt
    14341 atagatagta agcaaataga aaaattcaat ataaagcaga taatttctct aataagcata
    14401 gtagttatga ttgcttttat cataattttt gatatgaatg ttgggcttgc agcttttgca
    14461 gtttcagctg tacttatttt tttcaatatt gctgatgaag gagaatgtat caaatcaatt
    14521 ccatggagca cgatagtaat ggttcttgga gtaggtgcaa tgatgacaat cgtagatgca
    14581 gcaggaggta ttgacttgat gagtaatgca ttatcatcac tgatgaatag taaaacagct
    14641 actccaatta tgagtatttc agcaggactt atgtctatgg ttagttctgc tttagcagta
    14701 gtttatccaa ctatgatgcc tatgtgtgtt gatatagcta aggcagttgg aggagtagac
    14761 ccactagcac ttattgctgc agttggtgtt ggaggttctc ttgctggtgt aagcccactt
    14821 tctactggtg gggcattgat tttagcagct atgggttcaa gtaagaaaga ctttaataag
    14881 gaagaacaaa ataaggtttt tgtacagctt ttcattatga gtgcagttgg cttattggtt
    14941 attgcagtag tatcaatatt atcatttaat gcaataacac atttaatgaa ctaattagaa
    15001 taactgaaaa taaatcatta aatttaactt ttaatattaa tcaatataat ataatttgga
    15061 ggggaagtta tgaaaaaagg agcattaagc aatataaagg tacttgacct tacaagagtt
    15121 cttgcaggtc catattgtac aatgatgttg gcggattttg gagctgatgt tataaaaata
    15181 gagatgccaa gaaaaggtga tgatacaaga ggttttggac cttttgtaaa tggagagagt
    15241 ttatactatg caaatataaa tagaaataaa aaaggtatca ctctaaacct taaatcagaa
    15301 gaaggaaaaa atatattttt agaaatggta aaacatgctg atgttgtagt agaaaattac
    15361 agaccaggtg taatggaaaa gttaggtctg ggttatgatg agttggctaa agttaacaat
    15421 caaataattt atggagctgt atcaggattt ggatgttatg gaccatattc agaacgtcca
    15481 ggttatgata ttattgcaca ggcaatgggt ggtcttatga gtataacagg gcaagaagga
    15541 ggagaaccaa cgagagttgg taatgctatg ggtgatgtac taggtggaat gaatttaact
    15601 attggtatac tcacagcact caacgctaga aaaataatag gaaaaggaca aagagtagat
    15661 gtttccctcg ttgattctgt tgtatcgtct ctcgaaactg gtatacagag atattttgat
    15721 tcaggacaac ctgaacttat gggtaataga tatgcttcag cctatcctta tgactctttt
    15781 aaggcaagtg atggaagttt tgtaataggc tgtggtaatg acaaactttt tgaaaagtta
    15841 tgtaaaaaag ttctttttag agaagacctt ttaatagatg agagatttaa aacaaatctt
    15901 aatcgttgtg aacattacaa ggctcttaaa ccagaaatag aaaaatggtc tgttaagcat
    15961 acaataaaag aagcagttga cttaatatca gaggctggag ttcctgctgc tcctatctat
    16021 aatcttgatt gtgttacaac agatgaacat atagcaaaag caagagaaat gattgtagat
    16081 attagtcatc ctattatagg aaatatgaaa gtcaatggaa atccagttaa gttgatgaca
    16141 acaaaagcta aaattgatat gccagcacca tctctagggg aaagtaacga ggagatttat
    16201 aatggttggc ttggttttga tagtgataaa ataaaagatt taaaagaaaa tggagttatt
    16261 tgattaaaaa atagctaaac acacttgtga ctttagtcat gggaggttca gttagaataa
    16321 tatcaaaaaa tattaaatca atactgtaaa taaaatatag aattgtcaga agcatttaag
    16381 atgggaaaag ctacttagac attgagtctt tgtggctttt cctattttca ttaagaattt
    16441 tatattatca gaatagatat gtactaaact aaagtattaa caatttaaat taatagaaaa
    16501 taaactacct aattatgttg aataaagact actttagtga aaacaaactt atagagatgc
    16561 tatttaaatt attttaatgg aaatatcaaa aatgagactg cattctcaaa aatgagactg
    16621 cgttttttaa gtattttctc gaaaatgaga caaaaatatt attttatggg ttttattgaa
    16681 gaaaaattct tctgtgaatt acaatttaat caattttaaa gttgaaaatt gttaaaaatt
    16741 tagtgaaatt tatgtatatt tcgtttattt tattaaaaat aacaattttt tactaaaaat
    16801 aaagaacttc aatggtgatt ggcatagtac ttgctatttt atattaacaa gaaatgtaga
    16861 aaaaataaca atgtataatg gggggaatat gatggaatct gtaatggaaa atttgaacaa
    16921 tcttaaggtg gaggttaagg acaaagtctg tgttattact ataaatagac ctaaagcttt
    16981 aaatgctctt aatagtgaca ctcttaggga actatcacaa gttattgatg tagtatcaga
    17041 aaatgaggca atattaggag ttattattac tggagaaggt aaagtttttg tagccggtgc
    17101 tgatatacgc cagatgcaaa actataaaag tgaggaaggc agaaaatatg caggttatgc
    17161 tcagggaatt tttgataaaa ttgaagctct tgaaaaaaca gtaatagcag cagttaatgg
    17221 atatgcatta ggtggtggat gtgaacttgc tatgagttgt gatattagaa ttgcatcaga
    17281 aaaggctata tttggacaac ctgaagttaa tttaggagtt attccatgtt ttggtggaac
    17341 tcaaagatta tcaagacttg ttggaactgg aatagctaaa gagttaattt ttacagggag
    17401 acaagtaaat gcagaagaag ctaaatctat tgggcttatt aataaagtgg ttccaagtga
    17461 tttactttta gaagagtcta tgaagatgat gaaccaaata gttgaaaaag cgccaatagc
    17521 aataagatat gcaaaagttg ttattaacaa agggatagat atggatttaa agaatgctct
    17581 tgaactagag aaagatattg caggtttaac ttttgctaca agagataagc aagaaggaat
    17641 gaatgcattt atagaaaaga gaaagccagt ttttgaaaat aagtagctat tataactaaa
    17701 attggaacaa tgtagaatat attcaaaatc taaatttcgt gaaaaaatac atatagttta
    17761 attttaaaag gagttaattt atgaatacgg gagtaattat aagtttagta gggattatca
    17821 tagctctatc tcttctagtt gtaatggtta tgaagggaat aaatattttt attatagcaa
    17881 ttgtatgttc atcattagtt gctataacag gaagcctaaa tgtgtatgat gcacttaaag
    17941 tggattatat gacagggttt gttggatttc ttcaggcaaa tttctttatt ttcctaacag
    18001 ggacattaat gggaaaaata atggagatta ctggtggagc aaaatctatt gctaagatga
    18061 ttgtaagatg gattgggaag gataaagcac tactttctat tccaatagct tgtggaatat
    18121 tagcctatgg tggagtaagt gttttcgttg taagttttgc agtgtttccg atagctttag
    18181 aaatttttaa agaagctgat ttgccacgaa gatttatacc agcagctttg acttttggat
    18241 gctcaacttt tgctatggtt gcaccagggg caccacaaat tcagaatatt gttccagcat
    18301 caacattagg gacagatatt atggctggag cagtaaatgg ttttatatca tgtgcagtaa
    18361 tgtttatagt tggaagtacc attttgtaca aaatggtttc aaaagaaaaa gccaatggtg
    18421 gtcattttat agcacatgaa tcagatatat ttgatgaagc agaagcaact aattctaaga
    18481 gagaaaatgg tcccaatggt gtaattgcct taattccatt gatagtgtca attttaataa
    18541 ttaatgtaaa agttaatgga aaagcgatag taccaattga ggtgggagta tttattggag
    18601 ctttattagt atatttattg ttaaataaat atcaagataa tactaaaata gttggacatg
    18661 ttggtgatgc atgtaaaact acagtagtag caatatgtaa tacttgtgct gtagttgcat
    18721 ttggttcagt agtaaaatca gcagttggtt ttgacttcat agttaatgcc atgactaata
    18781 ttcctggtcc tcctattgca ggggctgcag ttggaactac agttattgca ggtatttgtg
    18841 ggtcagcttc aggtggacta ggaattgcag ctccacttct tggaccagta tttttagcca
    18901 agggtgtttc cgctgcagca ttaactagga ctatggcaat ttcatcagca gcattagatt
    18961 cacttccaca caatggatat attgttactg taacaaatgg tctttgtaaa gaaacacata
    19021 aggatgctta tatgccaata ttctgggtaa ctgttttaac cccatttatt ggaactatag
    19081 tagcagtcct actgtttaca atgttcccgg gattgccata ggagaaaaga taaaaggtat
    19141 aaattatatt ttgatattat aaaatcaatt ttcaaaatat atacaataaa tttcatgttt
    19201 taatactgta aatatgtatt taaaataaca aattgaccat ataaggagga attgaaagtg
    19261 ttaaataaac cattagaggg agttaaggtt attgacctaa cgtattttgt agcaggtcca
    19321 gggacttcta aaatattagc tgactggggt gctgacgtta ttaaggtaga gccaagcttt
    19381 ggagacccag gaagaaagac aggggcaaca atgacaatgc caatagatga ttataataat
    19441 cctttttaca gcacatataa ttcaaataaa agaggtttgt ctataaatct taagagtgaa
    19501 actggaattg aaattatgga taagctttta agcgaagcaa acgtatttgt ttcaagttat
    19561 agaacaggag cattaaaaag actaggtctt gattatgaat cattaagtaa aaagcatcca
    19621 caccttatct ggggtcagat aaatggtttt ggcgattttg gacctgctaa ggataatgca
    19681 ggatttgata cagttgcctt ttgggcaaga agtggggcta tgcttgatat agcagaaaaa
    19741 gatacaagtc caataaatcc acctatagcc tttggagatg caacaacttc ttgtagttta
    19801 tctggaggaa tatgtgcagc tttgtaccag caagctaaga ctggaaaagg acaaaaagta
    19861 atggcatctt tatttgggca agcaatatgg aatgcatcat ctttattagc atctacacag
    19921 tttagtgatg agtatccaaa aactagaaaa aatgctattt caccagtaat aaattcttat
    19981 cgttgtaagg atggaaagtg gatattctta agtattttag agcatgaaag atattttgag
    20041 gcactttgta gattatttgg aagagaagac ttaataaaag aagagaaatt tgcatcttca
    20101 ttagaaagta agaaaaatgc tacagaactt attaatattt tggatggtga atttgcaaag
    20161 tttactcaaa atgagatggt tgaaaaactt actgctgctg atatagctca tgaaaaaatt
    20221 caacatgtta atgatgtagt gactgatgaa caggctattg ctaataacta tatatatgaa
    20281 catacaagta aaaatggaaa taagacaatg cttgcatcta ctccagttaa atttggaaat
    20341 attgaagtta acatgacttg tgatgctcca cttataggag aacattcaga tgagatattg
    20401 agagaacttg gatacagtga ttctgatata gaagctctaa ttgaatctgg aattgtaaca
    20461 atgaataaag aagcatgtga aatatgttaa taaacatgtg aagtatgtta ataaatagga
    20521 gggaatttta tggattttag attaacagaa gcacaattaa tgcttcaaag agtagcaaaa
    20581 gaatttgcag agaatgaaat agcaccaata gctgctgaaa cagataaaac aggtattttt
    20641 ccaagagagc tttttagcaa aatggctaaa ataggattta atggcattgg aacacctgta
    20701 gagtatagtg gttctggtgg ggcagatata gaaaaggtaa ttgttgttac tgagattgcc
    20761 aaaaaatgtg cagcatctgc agcaatatta tcaatacaca caatatatgc tcaagctatt
    20821 ttgaaatttg gtactgagga acaaaagaaa aaataccttc caatgatggc tgaaggtggg
    20881 tgtgtaggtg cttttgcctt aaccgaacct aatgctggtt cagatgctgc aagagcagca
    20941 acaactgcaa ttattgatga agaaactgat gaatatgttt taaatggaac taagtgtttt
    21001 atttctggtg gaggtcaagc agaatcatta ataatatttg cactgacaga cccagcaaag
    21061 ggaataaagg gaatgtctgc tatcattgtc gacaaaggta ctccaggttt ttcaatagga
    21121 aaaattgaag aaaaaatggg tattcatggt tcagaaactg cagagttaat atttgataac
    21181 tgtagagttc caaagtctaa cttattagga aaagaaggca aaggatttaa tatagctatg
    21241 acttgtttag atggagcaag aattggagtt ggagctcaag ctgtaggaat tgctgaaggg
    21301 gctttagaag aaagtatcaa atattctaaa gaaagagtcc agtttggcaa gccaatttca
    21361 gctttgcaag gtattcaatg gtatatagca gatatggcga caatggtgga atcagcaaaa
    21421 ttattagtat attatgctgc agatttgaaa gctagaggag aaaaacacac taaagaagct
    21481 gctatggcaa aatacaatgc gtcacgtact gcaagagagg ttacaaattt agcccttcaa
    21541 atccatggtg gatatggata tatgaaggat tatccattag agagaatgta cagagatgcc
    21601 aaaataacag aaatttacga aggtacttca gaaatacaca aagttgttat ttcaagagca
    21661 gtactaggat aggaggaaaa gaatgaatat agttgtttgc ttaaagcaag ttccagatac
    21721 taatgaagtt aaaataaata aagagacagg tactctaata agagatggtg taccaagtat
    21781 aatcaatcca gatgatagaa atgctttaga agaagctcta aaaatgaaag atgaactagg
    21841 agcagtgatt aaggttataa gcatgggacc tcctcaagct aaaagtgctt taaaagaagc
    21901 tttggcaatg ggagctgatg aagcttattt aatctcagat agagcttttg gtggttcaga
    21961 tacttgggct acatctacaa ttattgctgc tgctatagag aaggttggaa agtatgatgt
    22021 aatattctgc ggaagacaag ctatagatgg agatacagct caggttggac cagaggttgc
    22081 agaattttta gggataccac aagttactta tgcgaaagaa gtaaaggttc aagatgacaa
    22141 attactagta actcgttata cagagacagg ggattattta atagaagcaa agatgccagt
    22201 tttattaact gctataaaag agttaaacaa tccaagatat ccaagtgtca aaggaatctt
    22261 agaagcttat aataatggag atgcaaagat tactgtatta acacttgcag atttagatgt
    22321 tgatacaact caaattggat taaagggttc acctacaaac gtttataagt cttttgtacc
    22381 agttaaagac aagcataatg aaataataga aggtataaat aaaaaagaaa aagctgagaa
    22441 actaatagaa atactattcg atttgaaact agtataggag tgttaagatg atgagagcaa
    22501 aagttaatca aggtataaat ttaaatgatt ataatggtgt ttgggtaata ggagagcaaa
    22561 gggaaggcaa aattaatcct gttactatag aacttattgg tgaaggaaga aagcttgctg
    22621 accaattagg aaaagagctt gcagttgtga tagctggata tgaagtagag aaagaagtga
    22681 aggaattact tcactatagt gttgataaag tatattacat caatgaccct cttcttaaag
    22741 atttcactac tgatggatat gcaatttcaa ttgcaaattt aatcgaaaga aaaaagccag
    22801 aggttgtatt ggttggtgct acttctatag gaagagatat agcgcctaga attgcaggta
    22861 aggttggaac aggtctaact gctgactgta caaaacttga aatagattca acagataata
    22921 agttattaca aacaagacca gcatttggtg gaaatttaat ggccactatt gtttgtccaa
    22981 aaaatagacc acagatgtca acagttcgtc caggagttat ggcaaaagct gtaagaaacg
    23041 aatcagagac tggaatttta gaagttgtta ctccagaact tactgaaaaa atgattagaa
    23101 ctagattagt agagatactt ccacaagaaa agaaatctgt aaatctaact gatgctagaa
    23161 taatagtatc aggaggaaga ggattaaaaa gagcagaagg atttgagctt ataaaagaat
    23221 tggctgataa attgggggca gagattggtg cttcaagagc agcagtagat tcagggtgga
    23281 tagaacattc tcatcaagtg ggacaaacag gaactactgt tagaccagaa ctatacattg
    23341 catgtggaat atctggagca atacaacatt tagcaggtat gagtgattct aaatatatag
    23401 ttgctataaa taaagatgca aaagccccta tttttagtat atgtgactat ggaatagtag
    23461 gagatttata tgaaattata cctgaaatga tagaatcatt aaataggtaa cttttagaaa
    23521 acattgaata tgtagaatga taagtcttat aatattgtat tgtaagactt attatttttg
    23581 ctgaaggtta tagtggggag atgaaacaat gaaagagcag tggtataagg atatatttgc
    23641 aagagtatta tctatgactg atgatggttt tattgttgta aatacaagtg gagtaataat
    23701 agatattaat gataaatatt gtgacttttt aggaaaagaa agaaaagata taataggaca
    23761 aaatatacaa agtattatac caaatacaaa aatgctagat gttatgaaaa ataagtattg
    23821 tgaagaagga gctatacatc attattcagg tggaaataca aaagaaaaaa gtgtaatagt
    23881 aagtaggtct tatgtggaaa atgacaatgg agaagtagtt gcaggagtag ctcaagttaa
    23941 atttagattg caatcatttg atgtagctaa aaagctaatg tcagaatata tggagctcca
    24001 atattataaa gagcagttta aggataactg tggttttgat aagctcatag gtgaaaatag
    24061 agacttcata gaacttaaga aaacaggtgt gaaagcttct aaaacaaact ttccagtact
    24121 tttaacgggt gaaacaggta caggaaaaga agtctttgct agagcaattc acaataatag
    24181 cagtaggtca gataaaccta tggttagtat aaactgcgct gcaataccag aagaattatt
    24241 agagtcagag ctatttggct atgacgaagg agcttttaca ggagcaaaaa agggtggtaa
    24301 aaaaggtaaa tttttagttg cgaataatgg tacaatcttt ttagacgaga taggtgacat
    24361 gcctttgacc atgcaagcaa aacttttaag agttcttcag gaaagtgaga tagaaccagt
    24421 gggaggtctt aaaactataa agatagatgt aagagtaatc tctgccacaa gaaagaattt
    24481 aagtaaaatg gttgaagagg gattatttag agaagaccta tactatagat taaatgtaat
    24541 aaacattcat atgatggaat tgaaggacag gcaagatgat attttattgc tagcaaatta
    24601 tatattaaac aaattaaatg ttgaatacaa ggaattgaag gttttaagtg ataaggttaa
    24661 aaattgtttt attaactata cttggccggg aaatataaga gaactacaaa atgtaataaa
    24721 aagtgcctat gctgtaagtg atgatatggt cattatgatg tgtgaccttc catctaagat
    24781 ggataatatc agcagagtag ctcaatgtaa tgtggatagc aattgttcaa ttcatgaaat
    24841 ggttgagaat tatgaaaaga gcttaattat tgatgtgtta aggaagtata attggaaatg
    24901 ttctaaggca gcagaggtta tgggaataca caagagtctt ttatataaga aaataaaaaa
    24961 gtatgaaatt gaattaaata attaagataa attgaattaa ggcaatgcta aaaaagcgcc
    25021 cttattcaaa gcgaactgta taaactgttt tatgcagtta aaacgtgtaa aagtagatgt
    25081 gaagtactaa tgtcaatcat tagtactttt ttattgtatt tataattact atctatattt
    25141 cagtatcttt tgatatctaa gattattatg tttaatttag gatataacaa aaccctctta
    25201 gttatggaca gttttatata ttttaactgt ctactaagag gggatagttt agtttaaatt
    25261 tagagtaaat tttatctagc atttataaaa aatattttga atagcttttt tgttatttag
    25321 tcataatttt ctacttcttt atcaagttct ttgccacaag aatcacactt atatatagca
    25381 ttgtatccgt aatcatattc atcaactatt ttcttttgtc taaatacacc accacactca
    25441 cataggaaac caatttttat aagtgtaacg ataaattgtg attttataaa ttttatatca
    25501 ttacatttat cgttagtgta aaatgtataa atataagagt tatcgcactc atctcttaat
    25561 tcaaatcttt caatatatgt gttatttttt aattcctcaa attcttcttt agttaaatat
    25621 gatttttgtt gcaattcatg taaacgctta atttggtcca ttatttatat cctcccaata
    25681 attttagtat tttaagctta gataaggaat ctaagtttta ttaaatttat cccaaggaat
    25741 tatttaaatc atatttagtt ttattaatta caacatatat aaattacacg aaaataaaac
    25801 taattgtaaa aataatatcc tgtgaaaacc taaactacta accccttact aacccgaaaa
    25861 ctaaaaaaag aaaatatatc caaatataag tgatatataa ataaagatgt ttcatataaa
    25921 tttaacttta aatattctga caataatata tataaatata ttatagttaa aatataccac
    25981 atattttggg tattgtatac tggaattaga gtaattaatt tattttttaa catacaaatg
    26041 attttatgaa aaaaaacaag actcaaaaat ttttatattc tttgatagaa taaaattgag
    26101 agtaaattta ttgaatttta taaaatttat aaggggtgag tctaagatat gcatgaagat
    26161 aaaaatgata tatttgaatc aatagatact gaggattttg ataataaaac agaagaagaa
    26221 tgtttagagc tagtaagaaa aaatggattg aatttaatat acataaaaaa tcaaacagaa
    26281 gagatatgtc tagaggctgt tagacaaaac tgtaatgcaa taaaatgtgt tcagaatcag
    26341 acagaaaaaa tatgtataga agcagttaaa caagattgga gaatgttaga atttgtggaa
    26401 gagccaacag aagaaatttg tatgttggct attaaccaag atggaacagc attaaaatat
    26461 atagaaaatc agacagagga gttatgctta agagccgttg aaaaaaatgg tgcagctttg
    26521 gagtatgtaa aagaacaaac agaagaaata tgtatagaag cagttagaaa cagcgaattt
    26581 ggattggcaa gagtgaaaaa tcaaacagaa aaaatatgta tggaagcagt taagcattgt
    26641 agctataatc taaaatgggt agaaaatcaa acagaagaaa tatgtatgga agcagtgaga
    26701 caaaatgggc ttgatttgaa atttgtaaaa aatcaaacag aaacaatctg tttaagagca
    26761 gtgagacaaa atggaatggc attagaattt gtaaaggaac agactgttgg tatatgctta
    26821 aaggcagtaa gacaatatgg aatggcatta aaatttgtaa aagaacaaac agaagaaatt
    26881 tgtacagaag ctataaaaca agataaaaga gcacttagtt ttgtaaaagg agataaggaa
    26941 aaatacaagg ctctatatga taataatgaa ccatttgcaa agagatatgt tagaaatgta
    27001 atagaaaaag aaaacagagc attgattaaa aaaggagaag aaaatgcaaa aatcaaaatt
    27061 gcaggaaaac tttatgatag aggcatgtct tttgaagata tatcagatat agttgagatt
    27121 gaaataagca agttaaaagt gagtttaggt gttttttaaa gtaataaatg taggtgtttt
    27181 ttatgggaaa tagttaataa aaaaataatc gactagctct ttgtaggaca gcaaaattag
    27241 tgatataatt tgatgtataa taaattattt ttattagata agggggaatt aaagttgaag
    27301 attacagtat tataccaaac aagaagtgga aacacagaaa gggtcgctaa gctgatagaa
    27361 gatggagcta aaaaggtgga tggagtagat gtaaagctta tgagacttga taatattgat
    27421 ttagattatt taaatgaaag taaagcagta atatttggaa cacctactta tttagcaaat
    27481 acaacttggg aagtaaaaaa atggtttgat gaagattcaa aaaaagttaa tttagctgga
    27541 aaattaggag ctgtttttgc tacatgtgat tatatatgtg gaggtccaga tgttgcgata
    27601 cttactatag taggacattt gatggttaaa gggatgcttg tgtattctgg aggtggttct
    27661 ttaggaaagc catttataca tttaggacat gtacattcaa ttgaaggtcc agagttacaa
    27721 gatgaaaagg ctataatatt tggtgaaaga attgctacta aggcaaaaga actatttgct
    27781 taatttctat atgcataata atgattagag taaatttagg gttttattgg agatttgaag
    27841 taaaagttat aaaataaaaa attttccata aaattactca agatgaatta taatataatt
    27901 ataaataaat tatattatta aaatatttaa aatcaaacgt caatagcgag ggaagtttat
    27961 ggtatggcat atagaatatg agattttttc tgcaattata gttatttttt taatggtata
    28021 cttttttaga agtaaattta tacctacttt acaaaacaaa atatattgtg cacttttaat
    28081 attctcattt ttatttataa tttcaaatat tttaggttca ttttgtctaa ataatataga
    28141 caaaattcca atttttatta cttttttatt gaatcagata tacttattgt tattgccaat
    28201 accagcagca cttgtatcat tttatgttat ggctattatt tatcaagata taaggtatat
    28261 gaaaaaaaga ttattatttt tatctatacc acttataatt tgtataatct tatctattac
    28321 aaatcctttt acgcatattc tatttggatt gtcaaaagaa acaggttata tacgaggttg
    28381 tggatatgtt gcaacttttg catctttttt cttttatgca atatattcag catttttatc
    28441 ttttaaatat agaaaagcaa tgcatgaatc aaaaatatgg gctattagag gttttcttat
    28501 agtttcaatt gtggcaatta tcttacaggc aattttttta cagtatcttc ttacaggaac
    28561 tgcatgtgca tgtagtttac ttttgacata tctttctatg cagaatcgag gtcttattat
    28621 tgatgacctt actggtgtac tcaatagaca atcttttatt caagagctag atttgaatat
    28681 caatactgaa caatcaggat ttattattac aattgcgctt gatgatttta agtttatgaa
    28741 tgaaactttt ggaacaaaaa atggagatat tgcactaaaa gaagttggaa aatatttgat
    28801 tcagatacat gatgtaaacc atgtatacag aataggggga gatatatttt ctattgttgt
    28861 caatagtcaa ttaggtatag aaccagatga tattatcaga aagatagaag aaagatttaa
    28921 aaagccttgg ctagtagaag agataagttt taatttagca actagtattg ctgttgttta
    28981 ttacccagaa aatgcagaaa cgacagaaga tgtaattgtt gctatagatt tctctataca
    29041 tgaagcaaaa cgttctgagt caaggcgagt tgtttatgca gatgcgtcta taagtgaaaa
    29101 gataaagaag aaacatgtta ttaaaaattg tttaaaagaa gcattaaaaa atgatgggtt
    29161 tgaagtgtac taccaaccta tattttctaa tagcaggggc aggtttactt cagcagaggc
    29221 attacttagg ctagaacaca aagagttagg ttttatacct cctgatgaat ttattccaat
    29281 tgcagaacaa acaggattga ttaactcaat tggattagta gtctttgaga aggtatgtag
    29341 atttatagct agtgatgagt ttgaagattt aaaattggat aatatagctg tgaatctttc
    29401 tgtagtacaa tgtatgcaaa aaaacttagc tgatgattta ctttatctta tgaataaata
    29461 taatgtatca ccaactaaat ttaaacttga aattactgag actgtggcta tgggctcttt
    29521 taatataatt aaagaaacaa tggaaagatt aattgattta ggtgttaagt ttgcacttga
    29581 tgattttgga attgcttatt ctggagttac taatatgctt tctttaccat tttcagtaat
    29641 taagttagat aagagtttga tttggtctat gaatgaagat agtaggcata aacttacagt
    29701 tgagacgatt atagcactta taaataaatt gaatatgaag gctgtagcag aaggtgttga
    29761 aaccattaag tgtgctgaag atttaatagc tatggagtgt gaatatttgc aagggtatta
    29821 tttttctaaa ccagttccag aagatgtttt taaaaatttg ttgaaagaaa atacttttac
    29881 aagttaacac cctttatttt tttaattaca actttgttca ttgacactgc cagcgatata
    29941 ttataaaatt aacacaataa taaatattaa atttattata catattatta atattaatta
    30001 atggagtaaa gatttattat atattttatt taattatcct aaagtgagaa aggaagatgt
    30061 gacatgaata aaaagaaaat attagtgcca attgatggga cagaaagaag tatgcattct
    30121 ttggaattta taaaaggaat atttaaaaaa gatgaagttg aagtagaaat aatgaatgta
    30181 aaagaactag tatttattga tggcatatcc ctggctgaag agataaaaaa ttctgaaaat
    30241 ttaggaagaa gaatcttgga taaagcagca gagataatgg gagagtatga tgttaaagta
    30301 cattttactt ttggatatcc aggagatgag ataattagaa aagcaaaaga agataatgta
    30361 gattttatag ttatgacaaa atctactaaa aaaggtctta caagaatgat aggttcagta
    30421 acagcaagtg tagttaaaca agcaaaatgt atagtgatga ttgtaccgga gtagaattag
    30481 aaaggtattt gaaatatgaa taaaaagata gtagcagttt gtgaaagtga aagaagttta
    30541 aattctctta agacagctgc aaatgattta ggatttgatt tagtttatga aattcaagaa
    30601 aatgataata taaaaaatga actttctatt tatgatatag aagatgcatc catagtgtta
    30661 tttgttacaa gtgattctat agaaagcata gagaagattg atagatttat agatagagaa
    30721 ttttatgaag ttgatccaaa gtatataata gaggatgcaa aatctatagt aagtgaaatt
    30781 ttaatagact taaattaatc gtgggtgtcg cactaagaat agagcgacgc ctttttatat
    30841 attttacaca agaaataaag aggttgtatc aaaatataga taagactctt tttcattgtt
    30901 gaaatgatga aaatatattt gatttcatac aaaaaagagt acctcataac taaaaagttc
    30961 actttgagac actccatttt tatatgttag ttgcatttaa ggtaaaatat aagtttaatc
    31021 atgttgaaat aactgaatta catcttctaa atgattgtac attgatgtat aacctaagta
    31081 agagtcttta ctatcaaatg caatcattat cttgttatgg tggctaatca tatccttgag
    31141 agaatttcta tatttaaaac cgaagtattg gttagaagaa actgttttag gtattaactc
    31201 ataatatttt ataaaaattg gattatgaga agctaaaatt atctctttgt gaaattgcaa
    31261 gtcagcatca taacattctt ctatcaaacc atgagaaacc ttatccaatt catctattga
    31321 ctttaggtaa gtatatttta ttttttgaag ttctttagat gtagcattta aaattgctag
    31381 tttagtagct tcgctttcga taagttgtct tgctcttaaa gattctacat aaaattcttg
    31441 tatgttatga tttttataga tttcaccatc atcaaatagg tcaacttttt taaatccttc
    31501 aactatagga cttgaataag gcacagctct aagtattcct tccttacaga gtatatttat
    31561 ggcatttctt acaggtattc tacttatgtt aaataggtca gcaatctttc tctcacttgg
    31621 taatttacta ttaattttaa acgttccatt tagaatgttt aatttaatat aatcaataat
    31681 tttttcagtg gcatttaagc ttttcataaa aactcctaaa catataattt ttttatgatt
    31741 gtattatatc atagttaaga gttaaatcta cttttttata atatgtataa gacaggatag
    31801 aggccaaaat agctataata gccaagataa agtatccata ttgtattgaa gtatattccg
    31861 atattttacc aactatcatt ggaaatacag acattcctat agcataaatt gcttgaaaaa
    31921 aacccattgc agtagatttc tgatgttttg gtacattttt catagactcg ctagtaaggt
    31981 aagaaaggag tatacctgta gatatacctg gtagtacttg tagtacaaat attatattaa
    32041 tattttttat tgttggaact aaaaagcaat aggctgaaac taaaataaaa actaaaggaa
    32101 tccaaaattt tggtccatac ttagtacaaa atttagtaga agcaaagcca gaagaagcaa
    32161 cagcacacac catgtaaaat atagaagata gacctatgag ggtagaacta gaacctaagt
    32221 ttttaagaat ttgagtagta aatgacattg ttgtagacat ttgaataccc tgttgaatta
    32281 atgccataaa ggaaaaaaat acaagtcttt tatccttgca gatagataaa tattttttaa
    32341 ttgatatttt ttcaggtatt ttttttgaat tatgattttt tatatttaag gctagaatcg
    32401 ttccaataac tgaagacaat acactcatga tacataaggc tgtcattcct aatttttcat
    32461 aaaataaagt actcataaca aatccaatca acattcctag attgtttacc aatattatcg
    32521 tacttgtagc tttttgttga tgttctgtag aaaaaaagtt ggtatagtga accatgtaag
    32581 aaatccaagt tgatgatgat attccagata aaatgttagc tataagaaaa ccattgcctc
    32641 caggagaaaa gactcttata agagatgcta aaccagcaaa gaaaattcca gacagtataa
    32701 atattttatg tttatttata gaatcagcaa atactccaac aggaagcctt aataaacatt
    32761 gtgatattcc atatgcacct attattatac caatcatatt tgtagataca ttacatgcac
    32821 ttaaatatgg attttggaaa ggtatatata catattgtga aaaccagaaa aatgtaacaa
    32881 tagaaagtaa aagtaatttt tgattagata tttttttcat attatcctcc atatggtatt
    32941 tttataatgc aaataatata ccatttagat tttttaatca agtactttat ctattaaaaa
    33001 aaatttaaat atataattat tatttacaaa aaaattatac tttatagttg aattaagaaa
    33061 acgcttatga tactataaag ttaacaaatt tgaatatata acagtagacg tgttactggt
    33121 aatgcaggca agatcgaatc aatttttata gattatctat agagtactat gggtataatc
    33181 tatttatttg gttcgatttt tttgtttaat tggccataaa acaaaaagcc tatagttgaa
    33241 aatggaggat tttttatgga ttataaaaat atagctcaag aaattctact aaatgtagga
    33301 ggaaaagaga atgtaaatga agtgactcat tgtatgacaa gacttagatt taaagtcaaa
    33361 agcgcttcta aagtgaataa ggataaatta tctaaaactg aaggagtaat aactgttgtt
    33421 gagagtatgg gtcaaataca agttgtaatt ggaaataaag taaaaaaagt atatgatgag
    33481 gttataaaaa ttgtacctca atcaaataac gtaggtaaaa agaatgaaag tcaagaaaag
    33541 caaggtataa ttaattctat attatcagca gtagctggta tatttacacc tacaatacct
    33601 gctatagcag gggttggtat gattaaaggt attttatcag ttcttgctat gtattatatg
    33661 aataaaaatg gagtagatat aaaagaaacg caaagctata ttatcttaaa tgctatggct
    33721 gattctatat tctattttat gcctattata ctaggatata ctgcggctaa agtatttaat
    33781 gcaaataaaa taatatctat ggtattagga gctacacttt gttatccaac ttttactgct
    33841 ttgatggcag gtgaagaatc tgttagattt ttaggattgg cagtaacaaa agctacgtat
    33901 acatcatctg ttattccaat aattattgct atatgggctc tttcatacgt tgaaaaagta
    33961 ttagaaaagt atatacctga ggtaattaaa ataataatgg ttccaacttt atcattggtt
    34021 gtaatgttac ctgcaacatt atttttattt ggaccaatcg gaatttatat aggaaatgtc
    34081 ataaactttt cttataagta tatttatgaa ttaagcccag cattgtgtgg agcatttgta
    34141 ggtgggttat ggtgtgtgtt ggttatattt ggtgctcata gagcattatt accaataggt
    34201 ataagtgatg ttgctcaaac aggaagacag aatttattgg cgtttgcagg agctgcaaac
    34261 ttttcacaag caggggctgc tctaggagta ttctttaaaa ctaaaaatca aggactaaaa
    34321 acaatttcta tgtctgcaac tataacagct ttatttggta taactgaacc tgcaatatac
    34381 ggtgccaatc ttagattaaa aaaacctatg gtatgtgccg taatatgtgg tgcatttgga
    34441 ggtgcgataa tgggaatggg tggagcttat ggtaatgcat ttgcaaacca aggtgtttta
    34501 actatacctg tatatgctga agcaggtgca ttaggtttct taagttatct aggtggttgt
    34561 gctatagcat tttttggttc agctatttca acttatctag ttggatttga agatttggaa
    34621 gagtcttcta ataaggaaaa ttcatctata aaagtagaaa cgaaggatgg tgttattgat
    34681 ataacttcac ctgtagaggg cgaatgtata gaattgtcag aagtaaagga tgatgtattt
    34741 gcttcaaaag ctatgggaga aggtatagct gtgttaccta caaaaggagt aataacagcc
    34801 cctactgatt gtgaagtagc ttctttattt ccaacattac atgcaatagg attaaaatta
    34861 gataatggag cagaaatgtt aatacatgtt ggaatcaata cagtagagtt aaatggtaaa
    34921 tactttacca aacatgttaa tcaaggagat ttagtgaaaa aaggtgataa acttatatcg
    34981 tttgatatag ataaaataaa aaaggctggt tatgatgtaa ctacgccagt tatagtaaac
    35041 aatacatttg attttggaca agtggtttct tgtaaatcta gttatgtttc aaccaatgat
    35101 aatataattt cattagtatt agctggtaat taagttaatt tgactagaga taagtaaatt
    35161 gatttaaaag gaaataagta aatcaacaat taaatacatc taaaagtaag tttattgcaa
    35221 tgaattgtta aagaaaataa ttaatatagg gtaaatctat ctcaatgaaa taacaaagaa
    35281 aagagttaat atagagtgaa cttattgcaa tgaatcaaca aagaaaataa tcaatataaa
    35341 aaggagaaat atttatgaat acaggatttc caaaagactt tttatgggga gcatcatctt
    35401 ctgcatttca agtggaagga gcttgggata aagacaataa aggaaaaacc gtagccgact
    35461 ataattcttt taaaaagtct catttacagg cagatactaa agtcgcatca gacttttacc
    35521 ataattatga agaagatatt gaattaatga aagaattagg gatgaaaaca tatcgttttt
    35581 caatttcatg ggcaagaata ataccagatg gtgaaggaga gataaaccag aaaggtttag
    35641 acttttataa taagataata gacaaactaa tagagtgtga tattgagcca ttcgtaactt
    35701 tataccattt tgaccttcca tttaaattag tagagaaata taatggttgg gaaagtagag
    35761 aaactgtcta tgcttttgaa agatttgcta aaatatgctt taagcatttt ggagataggg
    35821 taaagtattg gcaacctcat aatgaacaga atttaattgt tagagtggag gagagaatta
    35881 atatatatga tgaaacagat tcatggaaga tagataaaat gcgtgctcag atggattata
    35941 atctttgctt agcacatgca ttagcagtca atgcatgtca tgagatgata aaagaaagta
    36001 aaattggagc agcagtatca tcatctgtaa catatcctct tacttctaag ccagaagatg
    36061 tatatgcagc tagaatgaat gataatttta aagtgtacta tatgcttgat atgcatcatt
    36121 atggagaata tccagggtat tatatgaagt atcttgaaaa aagaaatata gttcctcaca
    36181 tggaagatgg ggataaagag atacttaaaa aagctaaaat ggattttata gctgtaaatt
    36241 attataggac aaattgtgca gaagctttac ctgaagattc acaacatcca tttggattaa
    36301 gagaaggaac tgttgatttt agtatgtatg gactatttaa aatgtcaatg aatcctaact
    36361 tagaggcttc tgagtatgga gcagcaatag acccatcagg tcttagagtt gccttaaatg
    36421 aatattggca aagatatcac ttacctgtta taataacaga aaatggtcta ggagctaaag
    36481 atatattaga agatggaaaa attcatgatg actatcgtat agactattta agaagtcata
    36541 taaatgcatg taaactagct attgaagatg gtgtagagat gattggatat tgtccatggt
    36601 catttacaga ccttttaagt tcttctcaag gctttaataa gcgttatgga cttgtttata
    36661 taaatagaac tgaccatgaa gttttagatt taaaaagaat caagaaagat agtttttact
    36721 ggtataaaga agttatagag aacaatggaa tagtaaaata aacataaata tatattgagg
    36781 gttttagtat gtacattaca aaggtattaa ataattcgtt gctacttgca aaggatgata
    36841 atgatgaaga aataatattg atggggaaag gcattggcca taattataag gccgggtctg
    36901 agttaaataa aaaagatata gaaaagattt ttgttcttca tgatgaaaat ataaaaaaga
    36961 gtattataca attggcaaca gaaatagatg cagaatattt tggtatagct caaatgataa
    37021 ttgcatatgg aatagaaaaa tataacttaa aacttatgaa ccatatatat ttggccttaa
    37081 ctgaccacat tgcctttgca gtgagacgtt ttaaagaagg tataatgatt gaaaatcact
    37141 atttgttcga aatcaaggaa tttaatccaa aagagtatga tataggaaaa tatgctatta
    37201 ctgtttttaa ggaggttctt ggtttagacc taccagaaga agagattggt aatatagcag
    37261 gccattttat aaatgcacaa caagataatc cttatagtga tagaaataag agaagtgcta
    37321 aaattgtaaa tgctattttg caaatagttc attatcactt ttctattgta tataataaag
    37381 agtcatttta ttataggaga tttgtaatgc atctaaaggc cttttcacaa agatttctgg
    37441 ctaatgaacc atcaagagaa aaaatagatt ttatatatga gcaagttcaa aaaaattgta
    37501 aggaagagta tgaatgtgtg aaaaaggtag gagcttatat gtataaggaa tactccagag
    37561 aattaccaag acaagaggag ttatatttga tgattcatat tcataagatt ttaggagaat
    37621 tatgcgaaaa tagttagaat atcttaatat gctagtaata ttataaaaaa ttaaaaatta
    37681 actgcacttt aaatatgaat aattgcatta cttaaggggg ttgtcttaaa attgattttt
    37741 ttaattaaat ttgaagctca actccttttt taaaccttta tatcattaca actttaatgt
    37801 ttatacgcct gtacttcaga tgtatatcta ctttttacat ttctcaacat gcaaatctac
    37861 cattttttgc agtatgttag cagtatgtta attgaaataa actattgagt taaccctaaa
    37921 tttattctgg acttatagga atagttccaa agatacttta aaatattttc tggaatgatt
    37981 gcttatttca catatgtttt attgtgatgt tttgatttaa taaattcttc aactctgtat
    38041 atagtaaatg tattatcatg tttgttttat tcaagcacac ttataatact cttgattttt
    38101 tcacaatgat gaaatatact aatgggtgtt ataggtataa gaatagcatt acacttgaag
    38161 aagcaagtga taaatgagat ataaatcctc atatgataaa ctactatttc attgaggaac
    38221 atattctaag tgatgtcaag atactacaat atgactaaat tcctaatgat aaaaaagtct
    38281 acgaatgagt gtagaaaggg gaactaagat gaataaagtt ttaattatag atgatgataa
    38341 agatctttgt attttgttaa aaaagagtat ttcaattgaa cagattgaag caaactattg
    38401 ccattctggg agagatggac tggttgaact ttcaaaacaa gattatcagt tagtagttct
    38461 agacgtgatg atgccaggta tggatggttt tgaaactatg gaacaaatac gaaaatatag
    38521 cagtattccc atcttaatgc tgacatcaaa aagcgataat tacagcaaag tgcatggatt
    38581 gcgagctggt gcagatgact atctaaccaa accatttgaa attacagaat ttactgctcg
    38641 tgtactgtct ttaatccgac gttacacccg ttttaatcca aaaaatgagg aaccacagca
    38701 actttctttc aaaggtttgt tgattgacct tgaccagcat acagtgacta ccaatggcga
    38761 acctatgttg cttccaccca aggaatttgg tgtgcttctt tactgtgcaa ggcatcaggg
    38821 taagattttg acaaaacagc agatttatga agccgtgtgg ggtgagccat atgtatatga
    38881 tgacagcaat atcatggcta ttatcagtcg cctaagaaaa aaaattgaac tagacccatc
    38941 atctcccatc tatttgcaaa caataaaagg aattgggtat caattcaaca cggaggtatg
    39001 aaaatggatg aacaaacgat aattcttttc ttactcttgc tgtcgattgg tctacttttt
    39061 ctttccatat ttgctttttc caagcttggg catatttaca agcgcctaaa agatatagag
    39121 gagatactgg ctgatgtacg aattggagac gaaaatcgta aaatactaat taagccatgt
    39181 gatgttatgg ctccattggt ttatcagctt aatgagattg tctacgatta tgaaaataag
    39241 ttactttctc tgaaaaagtc ggataaagct agcagacaac ttatgacaag tttatctcat
    39301 gatgttcgta caccattaac aactctgatt ggttatctgg atgctgtaca cagtggtata
    39361 gttatcgaac aagagcggga ggaatacctt gaaatcgcta ggcgtagagc ctacgacctc
    39421 aaggattaca ttgatgttct ttttgactgg tttcggttga actctgatga atttacgctg
    39481 tcaatagaat ctgtggaaat tgcagagttg tcacgcaata ttttgaaaga ctggattcct
    39541 atattccatg aaaagaaact gaattttgaa attgatattc cagaaaatcg actaatggta
    39601 aacctcgacc cagatggata ttcccgtgtg gtcaataatc tggttcaaaa tgttcttgct
    39661 cacagtaagg ctcggcaaat caaaattacc atgagtgagg attccagaat ggtattactc
    39721 cgtgttgagg atgatggtgt tgggattgcc agagaaaatt taccacatat ttttgagcga
    39781 ctgtataagt gtgataaagg acgttcagaa aaaggaagtg gtcttggtct atctattgtc
    39841 agtcaaatgg tggagcgaat gggtggtcag atttccgtag aaagtgagat tggaaagtat
    39901 accatattta cagtgagctt accattaata taaaattgtt tttcccccat gtgacatgta
    39961 tacatagggg gattttttgt aagttataaa gttgcaaggt taatacaagg ttgttgcaag
    40021 gttaatgtaa gattgaggtg gtatgataac tttaataaac aaaggaggct tttattattt
    40081 atgaataatt taattattga aacaaaaaat ctcactaagc aatatggtgc tcaaaagagc
    40141 gtttctaatt tgaatattca cgttcagaaa ggtcgcattt acggattgct aggaagaaac
    40201 ggtgcgggta agacgacaac tatgaaaatg ttattgggtc taacaaaacc aactactgga
    40261 gaaattaaaa tatttggtca ggacattcac aataacgaga agaagcttct tcctcgaatt
    40321 ggatgtttga ttgaatcacc agggttttat cctaatctga caggaacaga aaatctcaaa
    40381 atctttgcaa ggcttagagg aataccaaaa aaaaatgcag tagaatcagc actggatgta
    40441 gtcggtttgc caaacaatga caaaaagtta ttttctcaat actctcttgg tatgaaacag
    40501 aggttggcga ttgctcttgc cattatgcat gacccacaac tgttgatttt ggacgagcct
    40561 atcaatggac ttgatcctat tggtattgca gaagtaagaa cgtttattcg tgatctctgc
    40621 acagaacgag gtaaaactat tttgatttcc agtcacattc tttctgaaat tgccttgttg
    40681 gcagatgaca ttggcattat tgaccatggt attttgttgg aggaagaaag tcttgcccaa
    40741 ttagaagaaa aaaacagtaa atacatacat tttgctgtat ctgatgcagc acaggcagca
    40801 aggcttctgg aaacccaact taacctgaaa aatttcaaag tagcagataa ttacaatatt
    40861 atgctatatg atacagatgt ttctgttgca gaaataaatc gtgctttcat tctaaacaac
    40921 attgaggtat cagaatctca tttatgcgaa gatactcttg aagattactt caagaaagta
    40981 acagggggtg aaggaattgc ttgatataat ttcatgtgaa ttttcaaaac tcaagcggtt
    41041 aaaatttata ctgatttcta ttttaggtgc ttgcttattt ccaattcccg caacaatttt
    41101 gattgcaaag gacaacttgc cctttgagca attgttcaaa ttagttgtca attttggata
    41161 ttttttgcta ttaccaattg tattaagtat tgttgctagc caactatttt ttatagaaag
    41221 agataatgat gtattaaaaa atcttgcaac agtaccagtg ccaaaaggaa aactggctct
    41281 ggcaaaattg gctgtgttgc tgtttatatc attgttctac tccgttgcag ggttaggagc
    41341 tactatcatt ggaggtttca ttgttggaat agtagagggg gttgctgtaa aattaggaat
    41401 gagcattgct tttggaatta tgttttttgt tactgtactt cctgttgtgg tactcattgt
    41461 atatttcaat cgcagctata ttttttctat tatactttct tttgtatatg ctattttcaa
    41521 ttttagtata tccttaaata ttatcaattt tgaaccaaat aacccactat taagcgtatt
    41581 acctgctcct gttataatgc gttggtggat ggcattttgg ggagatccca ctggcgaata
    41641 cacggtactt agacagccat atttgctctc aactcctgct tgtgtaggta ttttatgttt
    41701 gataaccatt atagcagtcc tgctgatttg tatgatatac aaaaagcagg agaattagga
    41761 ggtatctatg cttgatataa ttactacaga atttcaaaaa ataaaaagat ataatattct
    41821 atggattggt gttgttgctg ttctgttttc agcactattg gcagtttttc aggttgtaag
    41881 ttcacacggc agtgaccctc taacgtatga gagctttgca aacggagtta tctggaataa
    41941 tttcagtctt agttttccat ttgggattac acttattgga ggatatctta ttaaccgtga
    42001 atatacagac caaaccttaa aaaacatcct aactgttcct atttcattac gcaaattgct
    42061 agtgggaaaa ttaattgcgg ttggaggaat tactgtattg ttaagtcttt tcagcttctt
    42121 atgcacattt attttggggt tgttattttg caatatcaat atatctgtta tactcgttgt
    42181 aaaatcctta gttcagattt tgtctgttaa tctgtattgt tatgttgctg ttttgccgat
    42241 tattgcttat tttggtcgta aacaaaatgc atttctgacg ggtgtaggga ttgcatttgt
    42301 atacggtttt tgtggtgtgt ttgttgctgg aagaaatctg acagactttt atccaatcac
    42361 agcaggtctt ggtctagttg gatacaacaa tggtgctggt actgtttatc agccacttat
    42421 cggtgctatg actttgattg taattctaat cttgacaact attctacttg tatttacacc
    42481 taattatgat aaagttatga ccatatctaa gaaaaaaggg ataaagcata aaaagtattc
    42541 tcataaataa cataaatatt gtttctatta tttaagttgc tagacagtga aaagaaaaaa
    42601 tctgtcgtac agtggctata tgctcatgta ttcaagaagc tacagttttg atttttcata
    42661 actgtagctt ctttttgtat ttattaaatc acgactatca taatacttgc aataggtata
    42721 gcgacaagag agagtactgt catatgtgtt ttatatatta cattaagtat attctaaaat
    42781 atatgtttta aataatatat ttgaaaatag gaatatttaa ataaaaaaaa taatattata
    42841 tatagttgac aaaaattggc aaatgatata atatataaat atagaaatag taatcattac
    42901 tattattaaa aagggaggaa ttaattatga acttaaaagg aactaaaaca gaaaagaatt
    42961 taatggcagg atttgcagga gagtcagaag caagaaataa atatacatac tacgcttcaa
    43021 aagcaagaaa agaaggttat aatcaaatag ctgctatatt tgaagaaact gctaacaatg
    43081 aaaaggaaca tgctaaatta tggtttaaac ttttacatga tggtatgcct tcaacagagg
    43141 aaaatttaaa ggatgcagca gcaggtgaaa actatgaatg gactgatatg tatgcaaaat
    43201 ttgctaaaga agctagagaa gaaggatttg acaagatagc ttatttattt gaagctgttg
    43261 gaaaaataga gaaagagcat gaagaaagat acttaaagct tttagaaaac ttaaatgaag
    43321 gaaaaatatt taaaagagat gaagaagttg tttggcaatg tcaaaactgt ggtcatgtgt
    43381 atgtaggtac tgaagcacca gaaaaatgcc cagtatgtga ccatccaaaa gcgtatttca
    43441 atataaaagc tgaaaattat taaaaattat cattattaaa aaggaatgtt aactatgaaa
    43501 ttttctaaac aacgagaact gattttaaat gaaatattaa ataatccggt tcatcctact
    43561 gcggattacc tatatgaaaa cttaaaaaaa gataatccaa gtttaagctt aggaactgtg
    43621 tatagaaatt tagctcagct aacggaacat ggctttataa gaaaggttag tattccaggg
    43681 tatccagata gatttgatgg tcgaatagat aatcactatc atatcatatg tgaagtatgt
    43741 ggagaggtat acgatttaga atccgaagtt cttaataatt tacaagaatt aatatctgag
    43801 gagacagaca taaaaataac atcttataac ataagtttta aagggatttg taataattgt
    43861 aaaaggtgta gccaagtagg ttagttttca aattctaaaa ataattaatg aggtgagttt
    43921 atgtgtagtg aacaaaaatt ttttatatgt gagacttgtg gaaaccttgt aggaatgata
    43981 caaagtggtg gtgtacctat tttctgttgt ggaaaaccta tgaaggaact tgttcctaat
    44041 acaacagatg cagcagttga aaaacatgta cctgtaattg aagtggatgg aaataatgtt
    44101 actgttaaag taagtagcac aactcatcca atgactaaag aacatcatat agcatgggtg
    44161 tatcttatga ctgaacaagg tggtcaacgc aaatgtctag cagtagatgg agaacctgta
    44221 gttaaatttg ctttgaatga tgatgataaa gtgatttctg cctatgctta ctgtaattta
    44281 catggattat ggaaggctga actgtaatat ttaaataaat tgagtcaaaa aggaggctat
    44341 aaatgtattt tcatacaaat agcctcctat aaatttatat aaattcaagt tttaattttg
    44401 tttaatgtca atataatata aggagaaaat aatatgtcaa tttataaatg tagtgtttgt
    44461 ggatatattt atgatgaatc taagaatgat aaaacatggg atgaattaag tgaagattgg
    44521 gaatgccctg tatgtacaaa aggtcgtagt tattttggaa agataagtac tgtttactat
    44581 gaagaagatg aaaagatagc agaagacata gttgaagatg aatctaaatt aaatactgaa
    44641 aaagagggag atttaaatta cttaagtaca tatttaagaa gagatgatga agttgagaaa
    44701 catatggata taattcacga aatggctgtt acaggaaaat ctataataga acctatgaga
    44761 actaaactac cagtaatttc ttgggatgat attttaatta tgggtgctca attaaatcca
    44821 ttacctttaa atgagcatga tgaagtaaat acaacaacaa taataggaaa aaaagcaaag
    44881 aaacctatga ttatagaaaa tccagtttat atttcccaca tgtcatttgg agctttgtct
    44941 aaagaactaa aaatagcttt agcaaagggt gcagcccaaa ataagacagc tatgtgtagt
    45001 ggtgaaggag gtatattacc agaagagaag gaagcttcat acaagtatat ttttgagtat
    45061 gtaccaaata aatatagtgt aaatgaagaa aatcttaaaa attctgatgc tatagagata
    45121 aaaattggtc aaggaacaaa acctggtatg ggaggtcatc ttcctggcga aaaagtaact
    45181 gaagaaatag caaaagtaag aaataagcct gtaggtcaag atgtaataag tccatcttgt
    45241 tttgaggaaa tacaatccaa agaagattta aagaaacttg tagatgaact tagagaagtt
    45301 tcagaagggc gtccaatagg tgttaaaatt tcagcaggtc atattgaaaa agatatggaa
    45361 tttatagctt atgctaaacc tgattttgta actattgatg gtcgtggtgg agctactgga
    45421 gcaagtccaa agttgcttaa agatgcaact tcaattccaa caatatttgc tctttatcgt
    45481 gctagaaaat acatagatac acatggatta gatatagatt tggttataac aggtgggctt
    45541 cgtatatcta ctgattttgc taaggcaatt gctatgggag ctgatgcagt tgctattgca
    45601 agttctgctc ttatggcagc ggcgtgtcaa caatatcgta tatgtggttc tggtaagtgt
    45661 cctgtaggag tagctactca ggatgaggaa ttgagaaaaa gattacatat agaaaatagt
    45721 gctaatagag tggcaaactt tttaaatgta agtttagaag aacttaagac ttttgctaga
    45781 atttctggtc ataaagatat acatgattta agtgttgatg atttatatac tgttaactct
    45841 gaaatatcaa attatacaaa catacagcat gtatagattg aagtttgaaa ctattagatt
    45901 ttagatagct ataaaagtaa atgataaata tattttataa aagagagtgt cttaaaatga
    45961 actttttagt tcataagtca ctctttttta taaaatatat ttatcatttt agcaatgaaa
    46021 aagaatctta tctctttatt ttgagataga ctccttctat ttatgaaaat taaagatatt
    46081 aaattgtaaa atattctgtg atgtcgtact attaaactaa agattctgta ctttaaagta
    46141 aataaaaatt taaggagtga ttattatgga aagattgaag atacaagttt tagtcgacaa
    46201 taatacttat attgatagat actttgttgg agaaccagca gtaagctatt atattgagat
    46261 tgatggaaat aggattttgt ttgactcagg gtattcagat gtattcatat caaacgctga
    46321 aaaattaaat atagatttag gaaatttaac tcatgttgtt ttttctcatg ggcataatga
    46381 ccatacaaga ggtatccagt ttttagaaaa taggtatgat ttatctacag ttgaacttat
    46441 ttcacatcct aactgtttta tacctagaaa acatggagag aaaagcatag gagctccatt
    46501 ttctgctgag gaaattaaaa atatttttat gtataatcct aaggataagc catttaatct
    46561 aagcaagaat tgtgtgtttt taggtgaaat accttctata aatgattttg aaaaaagatc
    46621 taaaattggt aaatgtaaaa taggagattt gtgggaagat gattatgttt tagatgattc
    46681 tgctatagtt tgtaaaactg ataaaggtat ttttattgtt acaggatgtt ctcatagtgg
    46741 aatttgtaat atagtagagt atgctaaaaa ggtatgtgga gatgatagag ttattggtat
    46801 actaggtggt tttcatcttt ttgaattgaa taataggtta gatagtacaa tacaatattt
    46861 ggataaagaa gaaataagaa tgttgtaccc ttgtcactgt gtttctttta aggtaaaagc
    46921 gaagatgaat gaaatattga atataaatga agttggagta gggctgacca taagtatata
    46981 gtatttgaaa gtatataaga tttaagttga aggttaaaaa gatattttct atagaaaata
    47041 tctt
//
LOCUS       DAEORM030000028        46422 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.028, whole genome shotgun sequence.
ACCESSION   DAEORM030000028 DAEORM030000000
VERSION     DAEORM030000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 46422)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46422)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 46422)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46422
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.028"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            457..4002
                     /locus_tag="KRH23_002071"
     CDS             457..4002
                     /locus_tag="KRH23_002071"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase domain-containing protein"
                     /protein_id="HHS5225351.1"
                     /translation="MNRLKPRILGISILFIIIIILTCGAVFKFKFKLDNKLKETTHTY
                     LSEFTEHNIINLKTRLSGQFDMLESIANFIGNLNNINDEMVIDLMDSDVKRSSLIRMT
                     ISTLDGECYSNDGITHNVQDRDYFKKAKNGEKNISEPLKSIVNNKEIIVLSTPVYKSG
                     KIVGVLSGIYDSKKLNELLGLSAFDEKADVFVAKKNGDIVAQKTNKNRKTLSCIFQLF
                     DKDNCDEDDCLKTIKENMKNDKSGYFNYNLDNEKFMLNYQPLGVNDWYVFSVVPNKIV
                     SIQSENISYDVYIFALEILLVILIFIIYIACIINNNTKIIINEKEKFKVLTDNILGGV
                     KTCLKDEYMTMTYVSQGFLELTGYSCEDLNKIFKNRFKDMIYKDDLDKFNCIILNQLE
                     KQDKIEVEYRIVRKDGSIIWILERSKSINDNKGSECIQGVLTDITELKKIQEELDSKR
                     FEIQAINDSIVGGIVITEINDDFDSIYLNEGYLNMIGYTRKQLEDELNNKLIKLIFKD
                     DRTELINSINKQLKLSDTFASEQRVEKRDGTIIWILLKGRKMIYDNGKSVLCCVIVDI
                     TSAKLLEQELKKSEERHEIILKQTQNIIIEWDIEKDKMNISPNWYNKFKYDPITENAT
                     KNIIKSVDIYHDDMDKFISLIKLTSQGSEYEECEIRLRTRDTIYAWFSIKATTLFDNN
                     GKPYKVVGSLTDIDESKREAEKLKERAEKDPLTDLYNKKASQSLIEEYITLDKKRKGA
                     LMIIDIDDFKGINDNLGHLYGDAVLSEIANDLINLFRATDIVGRIGGDEFIVFIKDIS
                     ETRDIINKAEELVKTFERSFLGKGRNYKISLSVGIAKFPQDGMDYMTLFRNADMALYS
                     AKGKGKNCYTLYDKKIDKVQYITNTRNAGDSDNVEMSFKEHITNYIFDILYESSDIEV
                     AVNLILSIVGKHFNVSRMYIFENSDDNRVCKNTFEWCNEGVTPEINNLKNICYKDLGN
                     YLLNFNADGLFYCNDIENLGSDVKKVLKPQGIRSILQCKILEGNEFRGFIGFDECSYN
                     RMWTNDEVNTLTFISKTLSMFLLKMRIQSKLEESLTIQKSVMDNMDIWAYVVDRNTYE
                     LLFINKKMLESAPNTHVGDLCYKAIWNNQDKPCKKCPMIYLKDGDDTYKSFMHNKKFE
                     VQANITTTTLKWFDGKDACLIFGSEITSIEAEENT"
     gene            4187..6121
                     /locus_tag="KRH23_002072"
     CDS             4187..6121
                     /locus_tag="KRH23_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YgiQ family radical SAM protein"
                     /protein_id="HHS5225352.1"
                     /translation="MENKFLPISKQDMIDRGWEELDFVLVTGDAYVDHHSFGTAIISR
                     VLESAGYKVGIIAQPDWRTTDDFMKLGKPRLAFLVNAGNMDSMVNHYSVSKKHREKDM
                     YSPGGKMGYRPDRATIVYCNKIREAYSDVAIVIGGIEASLRRFAHYDYWSDKVRKSML
                     IDSGADLLVYGMSEKQIVEVANALNDGYDPKYIRHIDGTCYISDTLEEIYDKYILIPS
                     YKEICEDKMKYVEAFKIQYDEQDPFRGNIIVQPHGSKYLVQNKPEKPLSREELDEVYG
                     LPYQKTYHPVYEKFGGIPAIEEVKFSIVSSRGCFGSCSFCAITFHQGRAVQSRSEKSI
                     IDEAIGITNLDDFKGYIHDVGGPTANFRRPACKKQITKGACKNRQCLSPSPCKNLDAD
                     HSEYLHLLRAVRKLPKIKKVFVRSGIRYDYVMADKNNKFIRELIEHHVSGQLKVAPEH
                     ISEEVLKYMQKPAGKTYDKFRQKFFAINEELGKKQYLIPYLMSSHPGSTLNSAIELAE
                     YLRDTHYQPEQVQDFYPTPGTLSTTMFYTGIDPLTMKPVYVPKSKRDKAMQRALLQYR
                     APRNYDLVYSALVEAGREDLIGFGHRCLIKPKNEKPYFNRNNSKKNVSKGTNKNKKTN
                     TNNRSNKNQQKSSTKKKKKH"
     gene            6227..7222
                     /locus_tag="KRH23_002073"
     CDS             6227..7222
                     /locus_tag="KRH23_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HHS5225353.1"
                     /translation="MKKYISIILLVVLTMVVLVGCSPGKDNPKNKELSVVKQVKVAVP
                     DGLPAVAIAKLANENPEIKEGYETVYSIEKTPEAISTRVMKKDADIAIVPSNMAAIAY
                     NKTSSYNIVGTVGMGSLYLVSTENIKDYSDLVGKEVGCTGKGLTPDITIKSLLLQKDI
                     NYSDIKFNYVNSASELVPLLATGKVKTGIVPEPALSALMSKNPDIKIIKSLNDSWKEV
                     SGSKDGYPQSTLIVKSEFLRDNKDFVDSFVGQLSNSIDWANKNPEELGAYSEKIKIST
                     ESKIIGKSLERANLKYIPVKDMIKDYKNYYEKLANFDDKTLGGKVPDEAIYFVEK"
     gene            7194..7979
                     /locus_tag="KRH23_002074"
     CDS             7194..7979
                     /locus_tag="KRH23_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHS5225354.1"
                     /translation="MKQYTLLRNKKNKEQFIDKMEVTLSCVILLFLWQIIALKIDNDI
                     FLPTVGQVFNSIKEIMLNSSFYIDILYSMGRCFFSFLLAMIFAIILSIVSYLNRFFRN
                     LLKPINALTRSIPTMILVVLALIWFEKDSTPFIVGFTIVFPILYDNVLGAILNIDKNL
                     LEMANVYKIRFIDKVLKIYLPAIKFQIISILVSTFSLSLKVAIAGEVYSQPTYGIGTM
                     IQTEKINFNTSGIFAWIIIVLLISAILQIAQKFLARRAFLWKR"
     gene            7967..8665
                     /locus_tag="KRH23_002075"
     CDS             7967..8665
                     /locus_tag="KRH23_002075"
                     /EC_number="7.6.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHS5225355.1"
                     /translation="MEKIKLSIENINKRYDSRIIFRDFNIDFYVNEVNCILGKSGCGK
                     TTLLNIISGIIKNDTNNLNIKENLNRVGNKLEASYIFQDDRLIDWLTVEENIKIVVNK
                     YYNKTQLNKICDEYLELVGISDYKKFYPQMLSGGIRQRVNIARAFIYPSKNIIMDEPF
                     KSIDAKNTQLIMDNFRNILRKEKRTVLFVTHNIEEALFLADRIFILGDSPIRIKKILK
                     NSKELEKNEVLKLI"
     gene            8788..9261
                     /gene="ybaK"
                     /locus_tag="KRH23_002076"
     CDS             8788..9261
                     /gene="ybaK"
                     /locus_tag="KRH23_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0002161 - aminoacyl-tRNA deacylase
                     activity [Evidence IEA];
                     GO_process: GO:0043039 - tRNA aminoacylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="HHS5225356.1"
                     /translation="MVKTNAMRILDSNKIDYKVMSYEVKSEHVDGVEVAHDIGRDVNE
                     VYKTLVTQGVSKNIYVYVIPVHENLDLKKAAKVAKEKSVEMIHVKDINKLTGYIRGGC
                     SPIGMKKLYKTFVNESAKNLDTIIVSAGKIGYQIELSPFDLQRLIKVEFVDVIKK"
     gene            9458..10297
                     /locus_tag="KRH23_002077"
     CDS             9458..10297
                     /locus_tag="KRH23_002077"
                     /EC_number="4.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate hydratase"
                     /protein_id="HHS5225357.1"
                     /translation="MRKIKSEQIVEQVKKLCIEASLYLGEDVLSCIKEKAKSEKSEVG
                     KNILNILVENAEIAKEKNIPICQDTGMAVFFVEIGQEVLIEGDTLTDAINEGVRQGYE
                     EGYLRKSVVSPINRVNTKDNTPAVIHYDMVKGDKIKIEFAAKGFGSENMSKMKMLKPS
                     DGLEGIKKFIIDTVSEAGPNPCPPMVIGVGIGGTVDKCAQIAKKALFRELGEFNKDEN
                     IAKLESELLTAINKLGIGPQGLGGTTTALGLNIETFPTHIAGLPVVVNINCHASRHKK
                     VVI"
     gene            10310..10858
                     /locus_tag="KRH23_002078"
     CDS             10310..10858
                     /locus_tag="KRH23_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016836 - hydro-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S-containing hydro-lyase"
                     /protein_id="HHS5225358.1"
                     /translation="MIKITTPVNEIDIAKLNCGDTISLSGILYTARDAAHKRLIDCIN
                     KGEELPFDVYGQGIYYVGPTPTKPGEVIGAAGPTTSYRMDDLTIPLLERGLRLMIGKG
                     KRSDEVIEGMQKYGAVYLAAIGGAGAYISNSIKSCEIIAYEDLGAEAIRKIVVEDLKL
                     TVAIDSYGNNIYEQGRAIYECK"
     gene            10924..12105
                     /locus_tag="KRH23_002079"
     CDS             10924..12105
                     /locus_tag="KRH23_002079"
                     /EC_number="1.1.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004471 - malate dehydrogenase
                     (decarboxylating) (NAD+) activity [Evidence IEA];
                     GO_function: GO:0004473 - malate dehydrogenase
                     (decarboxylating) (NADP+) activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent malic enzyme"
                     /protein_id="HHS5225359.1"
                     /translation="MSKDYAKLALEMHEINKGKVSVESKVEVKTKDDLSTAYTPGVAE
                     PCLKIHENQDDVYRYTSKGNLVAVVSDGSAVLGLGNIGAEASIPVMEGKAILFKQFAD
                     VDAFPICLKTNDVDEIVKSVELMEPVFGGINLEDISSPRCFEIEERLKKSLSIPVFHD
                     DQHGTAIIVAAAIINSIKLIENKKIEDLEIVINGAGAAGIAIAKILLNMNVKNIILCD
                     RSGALEASIENLNYVQKEMLKVTNIRNEKGSLKDIIKGKDVFIGVSGPGAVTKEMVES
                     MSEKPIILAMANPTPEIMPEEAKLGGAFIMGTGRSDFPNQVNNVLAFPGIFRGALDVK
                     AKEINEEMKIAAAYAIANTISDEEICPEYILPDVFNKNVVKNVAKAVKEAAIKTKVNR
                     I"
     gene            12397..12786
                     /locus_tag="KRH23_002080"
     CDS             12397..12786
                     /locus_tag="KRH23_002080"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HHS5225360.1"
                     /translation="MMEYKVNDQELNASMFIPFVNRIWPGDYDMDKTQTALSKTLNIT
                     AYDDKVLVGCLRVLSDGYYFGTITELLVLPEYQKQGIGSKLFQLAKENTPTMLYFGAQ
                     PGVEAFYEKNGCQRSLQSYIIKKKDSY"
     gene            12936..13199
                     /locus_tag="KRH23_002081"
     CDS             12936..13199
                     /locus_tag="KRH23_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HHS5225361.1"
                     /translation="MEETKFCQCCAMPMGQTDELYGTNKDGSKSTDYCSYCFKDGEFI
                     ADISMEEMIEVCIPHMLQSNKDMTEDEARTMMNNFFPTLKRWK"
     gene            complement(13328..14170)
                     /locus_tag="KRH23_002082"
     CDS             complement(13328..14170)
                     /locus_tag="KRH23_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CvfB family protein"
                     /protein_id="HHS5225362.1"
                     /translation="MINIGDFNKLTVKRKTEFGYFLDGQTNNTKDDILLHNRLIGKNE
                     INIGDEVNSFIFKDSDDRTAATLIPPLAKVGDVAHLKVVDNTDIGTFIDMGLPKDILV
                     PFKAKTYPLFRDEKYLFYIYLDKSKRIAATTDIDSYLLTDHTYNVGDIVTGVVYGFQT
                     NNSAMICVDNKYAGVILHNEYFTELKTGDVLENLHVIKIYEDGKLGLSPRGNRKDELD
                     TLENKILSYLEGSDGYMRFNDKSDPKDISILFNSSKKNFKRALGVLMKKGLIYQDEEG
                     TYLK"
     gene            14465..15199
                     /locus_tag="KRH23_002083"
     CDS             14465..15199
                     /locus_tag="KRH23_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HHS5225363.1"
                     /translation="MKIVNKSSNIPLHTQLSSIIREMIETGELKEGDAIMPERELCNI
                     QNVSRMTVNKTIVGLVTEGLLYRVQGKGTFVAKQKKKYQFSNVKGFTDVMKEKGVNIK
                     TYILSFEMELPDDLVKRKLGISDNTTNIYKIVRLRYTDGEPFGLEIVYLSEEMCKGLT
                     KGILDNSSLYRVLNEKYGYKIQKAEQVMEPVILSDEESKLLETDEGALALKLHRNSYN
                     REGSPIEYTISIFRTDKYQYEIVLSE"
     gene            15209..16342
                     /gene="nagA"
                     /locus_tag="KRH23_002084"
     CDS             15209..16342
                     /gene="nagA"
                     /locus_tag="KRH23_002084"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008448 - N-acetylglucosamine-6-phosphate
                     deacetylase activity [Evidence IEA];
                     GO_process: GO:0006044 - N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HHS5225364.1"
                     /translation="MKCLINGKIILKNQILENKVLVFDEKIIDIADSVPKDCEVIDAD
                     GKYISPGLIDIHIHGNMGKDTMDSTDESIETISKSIMRHGVTSFLPTTMTMDKEHVYD
                     ALEVIKKAQNRKLEGAQVLGAHLEGPFINENYKGAQNEKFIINSKYEFIKEYKDVIKV
                     ITYAPEKDIDFDFTREIKRCTDIVLSIGHSNANYDQAKEAINLGVTNVTHMFNAMTGL
                     NHRDPGVVGAALTTNVYSELIADTIHINKDLFQFILNNKGKERLILITDSIEAGGLED
                     GNYSLGGQRVIVKGNEARLENGALAGSVLSLNKMVFNFLDNTNLKVNEAINLASLNPA
                     TSLGINDKKGSLEIGKDADIAVFDENLDCKMTLCLGDVVYKNI"
     gene            16441..17190
                     /gene="nagB"
                     /locus_tag="KRH23_002085"
     CDS             16441..17190
                     /gene="nagB"
                     /locus_tag="KRH23_002085"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004342 - glucosamine-6-phosphate
                     deaminase activity [Evidence IEA];
                     GO_process: GO:0006044 - N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HHS5225365.1"
                     /translation="MRVLVCKDYDGMSKKAAEMIAAQIVLKPNSILGLATGSTPVGMY
                     RDLVKKYNDNIVDFSDVMSFNLDEYYKLPISNDQSYDYFMKENLFNHVNIKPENTHLP
                     NGMADDIEKECMNYEASIDAAGGIDVQVLGIGRNAHIGFNEPDTKFAKRTHVVELTES
                     TIEANARFFKSREDVPKKAVSMGIGSILKSKKILLLASGEEKADAVYNTVYGDITPEV
                     PGSILQLHKDTIVIVDEAAASKLNPKDYKLV"
     gene            17365..17637
                     /locus_tag="KRH23_002086"
     CDS             17365..17637
                     /locus_tag="KRH23_002086"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5225366.1"
                     /translation="MLKIIMFSGILSSIIKLPIIGILPTGNIKNNTGISDSKKDGKQR
                     RSNLGISIYQLPSFLYSLINNSVPSNKPIPPEEIKLIKMYLLKSCI"
     gene            18297..19001
                     /locus_tag="KRH23_002087"
     CDS             18297..19001
                     /locus_tag="KRH23_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HHS5225367.1"
                     /translation="MSKLIYIADDEDNIRNLVKTFLKNEGHDVMDFKTGDELLEQFNI
                     KECDLVILDIMMPGSSGFEVCTKLREKSTVPIIMLTARDTDIDYITGITLGSDDYFTK
                     PFSPMSLVMRVKSIFRRIEFEKKQNYDKYSNSIDMELKFGDVIINKKNKIVTSKNVNI
                     DLTPNEYNLLTYLFENIDRAVSRDELLNKIWGYDIEVETRAADDTVKRLRKKILNTNI
                     LIETVWGFGFRLKEKS"
     gene            19003..19779
                     /locus_tag="KRH23_002088"
     CDS             19003..19779
                     /locus_tag="KRH23_002088"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5225368.1"
                     /translation="MKNGNDKNRIGKIKSKFKLKFSKKNISIKTRILLSILCLIIIVF
                     MIILVSFNVFLDTYIKTTANEELTKSTEIVEHMDSNFRPIKPPQDDGKLPPKVLSNFM
                     RNVQDKVRMAETQSDADAMVVDSKYNLIFPTREDDFLKNVDEMELIRECIQNEKLDLN
                     SDENTRISTRNKDYYISTVKITSIYGEQDKYLILFIDISKTLNLAQKINIVLISVMCF
                     AGILAIFTAVILSEKIAKPIKELCEFAKKNGSRRFQKNLL"
     gene            19733..20491
                     /locus_tag="KRH23_002089"
     CDS             19733..20491
                     /locus_tag="KRH23_002089"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: protein motif:HMM:NF014567.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HHS5225369.1"
                     /translation="MQKKMGQGDFKRTYFDFSDKELVELSTVMNKSAEYLDKYDNEQK
                     IFFQNASHELRTPLMSIKGYAEAIKYNVIDSKHASDIILEESDRLSDMVEDLLYISKI
                     DNITKDFELVECDLREVLSNCGARQNVRAINKGIKFIYEFDEEMVLFECDEKNISKAF
                     MNLIENALRYAKSEIKIVCKYNQKNIVVIIEDDGIGIKKEDLPHVFERFYKGVGGNHG
                     IGLSIVKSIVNKHGGRIYVENGKKGAKFTILFKL"
     gene            20696..22309
                     /locus_tag="KRH23_002090"
     CDS             20696..22309
                     /locus_tag="KRH23_002090"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0052621 - diguanylate cyclase activity
                     [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor domain-containing diguanylate cyclase"
                     /protein_id="HHS5225370.1"
                     /translation="MKEQLIFNITNLVTVVFEAFVIHMFLSDFLGQKEGYIKVVRYAK
                     LGFIICLGFCNLITLNPKITMPLIFILIFSTSFLYKGNLKTRLFTTVLLSIFFILSEI
                     VVTSIFVLFVKEGFEIMLENNSIRVLATILSKIVFLLTCKIICLFKKDVHLDMPIKYW
                     LPLFLIPIFSLFLSVSIFDVSKFFSLESLKFLSLISSVGILYINFIVFYLFKFIIDKT
                     KLSMKYELLEKEIIHKEELRLSNECYKIIVEQTDSVVFEWNIKENKSFVSQAWTEKFG
                     YNNACKNIFKEIKDKDLVHSEDKAIFEGFLESIKKTNMHNQAVYRLKKSNGEYIWCRT
                     SITSIYNDENELLRVVGVIVDVDSDIKKYEELRTRAESDSLTNIYNKGTFEKLVEETI
                     VMNTGDKKDALFIIDLDDFKEINDNFGHPFGDFVLKTFADKIQASFGSKDLVGRIGGD
                     EFVVYMQDYVTEVNLHKKAKELNRVLSDNYTDLSFSFDASVSIGIARYPQDGTSFFEL
                     FKNADRALYSIKASGKNSYCLFEEELYVQ"
     gene            complement(22672..23502)
                     /locus_tag="KRH23_002091"
     CDS             complement(22672..23502)
                     /locus_tag="KRH23_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HHS5225371.1"
                     /translation="MSQVSKNYFTTGEFAKICGINKKTLFHYDDIGLFSPELKKENGY
                     RYYSYHQLSIFGIISSLREVKMPLKEIKAYIDKRTPNLLIELLEKKTIDIKNEIEKLN
                     NIQALMESTISFTKNACNIDANTITLKEHEEEYLVKTPVTYKEQFLGDEEENFLYECI
                     NFMDNYELSDYGTIGSIIKGEDIINKDFESYSYLFTKVNKEYKKYPVSIRPKGLYVTA
                     YHKGSYETIYKTYEKLLNFFNQNNLRIGDFVYEEYLLYDISVRDSNEYLTQISAEVKM
                     "
     gene            23575..25302
                     /locus_tag="KRH23_002092"
     CDS             23575..25302
                     /locus_tag="KRH23_002092"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHS5225372.1"
                     /translation="MKKLIHFLKPYRVLIVVVLIFTFLQTLGTLYIPTLTANIVNNGV
                     VKGDIDYIVKTGLMMMIVAGITALSAVLVCKVSANLSSGFCRDIREAVFIKSQDLSIN
                     DFNNIGTASMITRSTSDITLIGQSVFMFIQLVLPAPIITVSGLFLAYSIDKAMTIIIV
                     VVMFLFMLSAFLVGKKLIKLFKMMQIKMDNMNRVLREVVTGVRVIRAFNRSRFEKKRF
                     DRTAIDYSETAISINKIFAVLMPIVMLIMNLGIVSIIWFGGMRVSNGNMEIGHIMALV
                     EYCILILFYLIMGVMVFMYIPRAGACADRVNQILDIEPEIVDGNGHKDTVSERGHLVF
                     KNVNFSYAQSEEPVLNNITFEAKSGEVTAIIGSTGSGKSTIANIIPRFFEIQSGEISI
                     NGQDIKKIPQKELRDKIGFVPQKAFLFSGTIEENIRYGKEDASIEEVKHAASIAQADE
                     FIYDMEDKYDSFVAQGGNNLSGGQKQRISIARALVRKPEVYVFDDSFSALDFKTDKRL
                     RKALKNEIKDSSAIIIAQRISTIMDANQIIVLNDGKIVGIGKHKDLLENCEVYKQIAD
                     SQLSKEELA"
     gene            25339..27201
                     /locus_tag="KRH23_002093"
     CDS             25339..27201
                     /locus_tag="KRH23_002093"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHS5225373.1"
                     /translation="MSEKRIDEQDIEVLSFEDGMSAEKAKDAKKTTKRLLKYMAKQKF
                     KILIIFISVLISSALTVLAPMVMGKAIDQLFNGIKTAVQTGTKFSVNFSTMGGIVSIL
                     LGLYLISAVFIYIQQYIMSGVAQNLVLSMRKDLSDKLNKLPLKYYDSHKKGETLSIVT
                     NDLEKVADSLQEGLMQLITAVVTVVGSIVMMISISVPLTIVSAITLLVSLGITVVIAR
                     KSQERFSENQKALGELNSNIEEIFTGQIVVKAFSKEKDTIRNFKILNQNLYNASRKAQ
                     FSSYAISPIIRFINLIGYVIIAVVGGIFASTGAMTLGSIQAFIQYVNQASEPTTEISY
                     IVNMLQAAIASAERVFTVMDEVEEIKDKESSKVISMPKGKVQFEHVKFGYSDDFILMK
                     DININLNAGDKIAIVGPTGAGKTTLVNLLMRFYEIQGGRITIDGVNIKDLKRGELRTM
                     FGMVLQDTWLFNGSIKENIAYSKSDATMDEIVRAAKSARVDHFIRTLPQGYDTILTED
                     ASNLSQGQKQLLTIARAILSDPSVLILDEATSSVDTRTEVEIQKAMNNLMKGRTSFVI
                     AHRLSTIRDADLILVMKEGTIIEQGSHKELIEKKGFYEELYNSQFTSEYDEDVV"
     gene            27534..28223
                     /locus_tag="KRH23_002094"
     CDS             27534..28223
                     /locus_tag="KRH23_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyphosphate polymerase domain-containing
                     protein"
                     /protein_id="HHS5225374.1"
                     /translation="MNKKLNYRFEMKHKITEADVLALKSRLYPIMKKDENASKDGKYL
                     IRSLYFDTPEDKALLDKLNGIAIREKFRIRFYNNDCSYIRLEKKIKHYNMTSKLSTNL
                     TKKEVINILNNDIEFLKESTNCLLREFYLKLKCERLEAKSIVDYNREAFIYPVGNVRV
                     TIDSDIKTSVNSVDLFNKDLPTVSVIDENMTVLEVKYDEFIPDFIKDLIQINKTTSTA
                     VSKYASSRLYI"
     gene            28340..29014
                     /locus_tag="KRH23_002095"
     CDS             28340..29014
                     /locus_tag="KRH23_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4956 domain-containing protein"
                     /protein_id="HHS5225375.1"
                     /translation="MTFNDIFKSSFIENVSGFSFVDSALALGSAFLVGLFIYMVYKKT
                     YMGIMYSRPFNVSLVALTMLTTFVILAVTSNVVLSLGMVGALSIVRFRTAIKDPMDLV
                     FLFWSLGSGIVLGAGLIPLAVMGSIIMGLILIFFSNKTISETPYILMVNCNNEDSEDI
                     ATDKIKKVFTKYQIKSKSVTPEKGIELVFEVRMKDGETSLINDLSQVDGVTNAVLVSY
                     NGDYVA"
     gene            29031..30938
                     /locus_tag="KRH23_002096"
     CDS             29031..30938
                     /locus_tag="KRH23_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CotH kinase family protein"
                     /protein_id="HHS5225376.1"
                     /translation="MKDKKFTLLISIMIIFLCAVVGVYSTSSNKSADLYSDVYIEKYF
                     NRDKVMEVNIEIDESDLKDMNENAIKEEFKVAKVTVDGDTYGNVGIRTKGNSSLISVA
                     NSDSDRYSYKINFDKYNTSQSMEGLTQLNLNNCYSDPSYMREFLTYSICEEMGLATPE
                     FAYAKVSINGEYHGLYLAVEGLKESYLENNFGNVTGDLYKSDEGSSLQYKGDDPESYS
                     NLIVESDKKTADWSKITKLLKSLDTGEDIEKYLDVDSVLKNIAINTALLNLDSYQGSF
                     AHNYYLYEQDGVFSMLPWDFNMSFGGFSGFGGGSQSIAIDEPTTGNLEDRPLISSLLK
                     NETYKTKYHKYLEEIVTKYLDSDYLENMTTKLHDMIASYVKEDPTAFYTYEEFEKNIT
                     SSIEDSSDNKGFGNKGFDNNNSNNSDSNNNSNSENKRSGNQSDEKEVNAELTSSVVKA
                     NTDNETKNKTTNDSESKNNTDKDKSGNDNNQKLEGPMGKGGKSIPGVLEVAEDMSKTI
                     KSQLSGETSSTKQNFGDESSSGIKGSEKFDEDMSGMPEPPEGMDGKMPPGMGNMDKGD
                     MNGKNGNMNMDRNQDNPREAGGFGNRGGGSVSKTTTYFKLILGGASMIIMSIMLVGVS
                     RVKRRRFIKSK"
     gene            31391..32080
                     /locus_tag="KRH23_002097"
     CDS             31391..32080
                     /locus_tag="KRH23_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YczE/YyaS/YitT family protein"
                     /protein_id="HHS5225377.1"
                     /translation="MLQKVLWKFLKLVVGLFICSVGIVLTINCNLGLSPWDVFHQGLS
                     NHIGITIGTASIIVGSIVVIADVVLGENVGWGTVFNMLLIGFFMDLLLYSNLIPEADS
                     LFVGIIMLILGLVLLSVGMVFYMGSGLGSGPRDGLMVAIQKKTGKSLKLIRGTIEVGA
                     LIVGFLLGGKVGIGTIISAFGLGYFTQMVFGLFKLDCSKIKHRFIVDDIKFIKVYMSG
                     EKKAAVQNIVK"
     gene            32516..33055
                     /locus_tag="KRH23_002098"
     CDS             32516..33055
                     /locus_tag="KRH23_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007286148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHS5225378.1"
                     /translation="MDIGEKIKRLRTEKQLTQEELANRCELSKGFISQLENNLTSPSI
                     ATLIDILEILGTNLREFFNEIDDERISFTKEDMFETEDEDLKYKLKWLIPNSQKNEME
                     PIIITLYPGGQYKEEKPHEGEEFGYVLAGSIYVHIGEKKNKVKKGESFYFRPKANHYI
                     SNEGKTTAKVIWVSTPPSF"
     gene            33074..34117
                     /gene="potA"
                     /locus_tag="KRH23_002099"
     CDS             33074..34117
                     /gene="potA"
                     /locus_tag="KRH23_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:1902047 - polyamine transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine/putrescine ABC transporter
                     ATP-binding protein"
                     /protein_id="HHS5225379.1"
                     /translation="MVENIIELRDISKHYEELTVLDNFNLDIKKNEFLTLLGPSGCGK
                     TTTLKIIAGFEYADDGKVLFEGKEINNLPPYERQVNTVFQKYALFPHMDVYENVAFGL
                     KIKKTPKDVIDAKVKEVLKLVALEGFERRQVESLSGGQQQRIAIARALVNEPKVLLLD
                     EPLGALDLKLRQEMQIELKRIQKKLGITFVFVTHDQEEALTMSDTIVVMYKGKIQQMG
                     TPQDIYNEPKNSFVAKFIGESNIFDGIMIEDYKVNFCNRDFECVDKGFEKNENIEVVI
                     RPEDIKMVKPEEGMLKGKVTSTVFKGVHYEIELNENGRLWILHNTKNAEVGTELGMDI
                     YPEDIHIMRKENN"
     gene            34119..34955
                     /locus_tag="KRH23_002100"
     CDS             34119..34955
                     /locus_tag="KRH23_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHS5225380.1"
                     /translation="MKRKSFLAYPYVVWSAIFVIIPLILVVFFSFTKESGGGYAFTLE
                     NYKEVIDPIYMKVFGRSILLAGGATLICLIVGYPVAYIISKARVSRRGSLILLFILPM
                     WMNFLLRTYAWVAILGKNGLLNTFLGWFGIQPLAILYTNFAILLGMVYNFLPFMVLPI
                     YTALSKMDNDLINAAHDLGANNMTVFRKIIFPLSLPGVMSGITMVFMPAVTTFAISRL
                     LGGGKIMLVGDLIEQQFTVVGDWNFGSAISIFMMIVILISMSIMSKFGDESDKEGGGL
                     LF"
     gene            35060..35734
                     /locus_tag="KRH23_002101"
     CDS             35060..35734
                     /locus_tag="KRH23_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHS5225381.1"
                     /translation="MARWNGFTWKWYGQLLQNESIMSALYYTIVIAILASVISTIVGT
                     ISAIGIHKMRGKSKKLILNVNYLPILNTEIVTAVALMSLFVFVKMEFGFTTMLLAHIM
                     FCLPYVILSVLPKMKQLPDNIEDAAMDLGATPIYALRKVILPQIKPGIVSGFLIAFTM
                     SIDDFIISFFNAGNGVSNLSIEIYGMARRGIKPEINALSTIMFAVVLGLLLLANKKES
                     IVRGIK"
     gene            35734..36786
                     /locus_tag="KRH23_002102"
     CDS             35734..36786
                     /locus_tag="KRH23_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0042597 - periplasmic space [Evidence
                     IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0019808 - polyamine binding [Evidence
                     IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0015846 - polyamine transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HHS5225382.1"
                     /translation="MIKFKKAISLIAVGMMTVTLFTGCNKATDSTKVLNVYNVGDYID
                     ESLIDKFEKETGIDVQYSTYDTNEMMYQKVKSGSTHYDLVFPSDYMVEKMKNEGLLEK
                     LDFKNIPNMKYLDKSFLNPVYDKTNEYSVAYMWGTLGILYNKKEVKDPMDSWNILWNP
                     KYKGNIMMFDSVRDTIGITLKKLGYSMNSVNPKEINEAKNLLMKQKDLVLAYVNDEGK
                     DRLLGGEVAMGMLYSGDAVTLMEQNPDLDYAIPKEGTNKWVDAMCVPTTAQNKKEAEL
                     FINFLLDPENAKVNAEYIGYSTPNTGALKLLDPEITQNPVAYPSKEVLDKCETFEDIG
                     ENIKLYDKAWIELKSK"
     gene            37016..37864
                     /locus_tag="KRH23_002103"
     CDS             37016..37864
                     /locus_tag="KRH23_002103"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase domain-containing protein"
                     /protein_id="HHS5225383.1"
                     /translation="MNRINKKIDLLILALLVFIFLIVGIVILSIRTENKLNVFIMLAI
                     IFFIIMLTYLSNSVVGLITSSIIIFMYTSYILYNNITHNMDVEFISYMWIIATPVSSI
                     IMGNLNKSINELQNTNKKLSEQYKELVTIDSETGLRNLKIFYNDVNMEISKSIRHNTD
                     FSLMIVKLPYYGNLQTIFGENKTNKIVKYIGSNIIECTRNEDIIYSLQKDMIGILMPN
                     TSLEGSKVVKDRIKKRIKELNLDLNNRGKYVNIDVKIAFLQYKSSFGDSINFKNIVEE
                     ELQYDV"
     gene            37854..39518
                     /locus_tag="KRH23_002104"
     CDS             37854..39518
                     /locus_tag="KRH23_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2334 domain-containing protein"
                     /protein_id="HHS5225384.1"
                     /translation="MMFKIFNKSLLKLVVVLSIVLTISNFSLSSYASEITSSTDKVLI
                     IYDSKKETAYNRDILNIMRTLLGRFSSDIELLKLSNYDGEINKNYYSHIFILGINENS
                     YNNDKNTKNLISSLNSYKGTICWLGYGIENLLEHKKYNLDYVGKTNNIVSVNYRGKSY
                     NLDEHYVFNIVESKDTSNKVIGSINDTLNKYPYIINDKNLFYVSKLDLDGVLFYIFCD
                     SLNDIFNIKTFDKGRIFVRIEDVHAFREPKNLVEIADYLSSKNIPFTIALIPAYVNPK
                     NHKVITLSESPEIVKAIKYMQDKGGTVILHGYTHQYKKEEVSGEGYEFWDGKKDEPLK
                     ENMKIFVKDRVLNGLRVCIENGIYPLAFEAPHYAMESEGYKELKKYFSTYMGQHQNND
                     KKFSTNTYPYIIRDTEEFNIFIPENLGYIDPEDKFTFQNIKENLDKLSIVRGFSGGFF
                     FHSYLNIEYLKNTIEYLEKQNIEFMNLRDFNNWVKVDEIQIRNNGDEIIVNYDKDLDE
                     LTKSDTRFKSISNISKVLIFIVSISVLIFVIIFIYFKRIDKKKFLK"
     gene            39567..40823
                     /locus_tag="KRH23_002105"
     CDS             39567..40823
                     /locus_tag="KRH23_002105"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006486 - protein glycosylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HHS5225385.1"
                     /translation="MRDLNVSEYLFVFSLFSIWSLLLINIILAMGGYIFYFKNFDKEI
                     KEIDEYPMISILVPAHNEAKVIGRTVESLLLLNYPKSKMELIVINDNSSDNSKEILEN
                     IKDRYNNYNFTIINTDSLTGGKGKSNALNIGYTISKGDFIAVYDADNTPDKNALRYLV
                     QTIVMNDELGAVIGKFRTRNKNKNLLTKFINIETLSFQWMSQAGRWQLFNLCTIPGTN
                     FILRRSIIEEIGGWDSKAIAEDTEISFRIYKLGYKIKLVPQSITWEQEPETVKVWIKQ
                     RTRWAKGNIYVLMKYIKNIFKQGRNKIVFDIAYFFSVYFLFLTSVIISDILFVLSISK
                     LVEISIPINFFLIWILSYLLFIIEVSISLTIEKGEATIENIFIVAIMYFTYSQLWLFV
                     AIKGMIEYLKDIIFKREVKWYKTERF"
     gene            40846..42927
                     /locus_tag="KRH23_002106"
     CDS             40846..42927
                     /locus_tag="KRH23_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0006011 - UDP-alpha-D-glucose metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cellulose biosynthesis cyclic di-GMP-binding
                     regulatory protein BcsB"
                     /protein_id="HHS5225386.1"
                     /translation="MKKFIISIISLVLFFSNISLIYKVNADETKVKNYKFERDITIDG
                     VIGSNSTFFEVNKNWDIEEVLLHLNFSKSQILNGDVSSLTVLINNVPIKSIKLNAKTN
                     YKNTLEVLVPKDYIIQGYNEIKIKTYKTISDKICQDDSNTGNWMVIHKESYISIRYKQ
                     KKVENSINEYPYPYAEIENNHKLDTTIVVPDNMTRGQTTAVFNLASAFGKITKNDVLK
                     LDVKLYSEMKNWSDDNIIYIGKPENTAEEILDILSIKEQTLLSSNCIIKQVDSPYNKN
                     KKMMVVIGSNEDDLIKASNLLIENRLSNQVLSSSVLVNKETNIKINREQKLNLGHLTL
                     KDLGYSDFLLEGAFNQQALFDVKIPTGKVLDDGSKIILNLRYSDNLDFEKSLVTVSIN
                     DVIVGSKKLDRSHSNNDKLELKIPKDIDNKNYYQVKLTFNLSIKNSNCVTRESNNPWA
                     YVSNNSYLALSTKENETLSFENYPYPFVRDDEFNDLTVIMPDYSGSQAMTWMFRLGVT
                     LGANINSHNGNINVIRGKEFSDKYKDTNIVVFGVPHNNSVIKMLNNNLNIKFDKNYSN
                     FISNDKISFIDDYGKNISTIQLIKSPYNNQKNIMVISSMNEKNLYLGMDYLLNKSKVN
                     DLKGDTLIIDEYGEAEDLAYNLKSKKEVKDSSWNMSINKTTKVFLMISFITIIVVMIL
                     SMLYIKKYKRR"
     gene            42976..44049
                     /locus_tag="KRH23_002107"
     CDS             42976..44049
                     /locus_tag="KRH23_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 113"
                     /protein_id="HHS5225387.1"
                     /translation="MNKFKLKRSILISLIILIFIFIVYFVSIELKDRSLVNNQYKGKI
                     KSANLSVDYEINQVMKDIDKLGLNTVNVPIIINVESINSDIMSIDNNSKEKAIKLIKK
                     LNKKGISTILEAYPWIENGKLYETDWNPINKKRFFYTWQNAILNELIIDVANPLDVNV
                     LNIGSNFVHLEEYQQNWGEIIDFVQSKFDGLVTYRTNWWYTKKDDLSSKLFYEQKLNN
                     NFFDKLDFISIAAYFELSNKPVNTVDELISALHSSTVNNRGQNIKQEIYNLYKAHRKP
                     IFFGELGFSNRESASSQPWNHTPSKVVNGEEQARCFEAYKKVFENEDWINGFSVFCVG
                     KIDDEKNFYPSKESIKVIKSWYE"
     gene            44103..45227
                     /gene="wecB"
                     /locus_tag="KRH23_002108"
     CDS             44103..45227
                     /gene="wecB"
                     /locus_tag="KRH23_002108"
                     /EC_number="5.1.3.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008761 - UDP-N-acetylglucosamine
                     2-epimerase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="non-hydrolyzing UDP-N-acetylglucosamine
                     2-epimerase"
                     /protein_id="HHS5225388.1"
                     /translation="MNDIKVMTVFGTRPEAIKVAPLIKELEKRENIKSIVCVTAQHRE
                     MLDQVIETFNINVDYDLDIMEKGQSLNDITCKILNKLPLILNKENPNIILVHGDTTTT
                     LATSLTAFYNKTLVGHIEAGLRTYDKYSPFPEELNRQLTGIIADMHFAPTNLARKNLI
                     SEGKPNNNIFVTGNTAIDALKMTIKENYNHPIIDEIGNDRMILLTSHRRENLGKPMKN
                     IFRAIKRIVDDFEDVQIVYPIHLNPKIRTIADEIFGKFPEKIHIIEPLDVADFHNFLN
                     KSYMIMTDSGGIQEEAPSLGKPVLVLRDKTERTEGIEAKTLKLVGTNEDRIYNSVSDL
                     LINKDNYVQMSKASNPYGDGNASKYIVDIIIKKFNCKYLN"
     gene            45305..46279
                     /locus_tag="KRH23_002109"
     CDS             45305..46279
                     /locus_tag="KRH23_002109"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HHS5225389.1"
                     /translation="MARKLIKNLGKSKSVKRVKLLFKKIFITVFIVASIVAIFNITKY
                     FEELYKVRDLKSTKIEYYMDVADEAGDGKVQLSWKALLAIDMVIHDEDLSNIKKKDTL
                     DIGEKFIVEDKNDKGEKVYKVKKFNKVLSELKFDSSQKSRARKYMKDLEYTYLGNKQL
                     DSSDEKIKFIKKLEDSAIREYIDYGILPSITIGQAILESGWGNSKLTKQSNNLFGIKA
                     DKAWKGKSVEISTSEHYNEKIVASFRSYNSLQDSVKDHSLFLINNKRYRKHGLFEAKD
                     YISQAQALENAGYSTAEDKKGNRIYAELLIDVIRSYNLQLIDNKVETK"
BASE COUNT        18536 a         4696 c         8019 g        15171 t
ORIGIN      
        1 ttactagaat tattatctgg taacttaagt tttgagtatt aatctaaagt atatgttttt
       61 atagggttta aattttatgt atacaaaatt aatttgctaa ctgaatcata taaaaagaaa
      121 aaatattttt tagagggaat gattagatag aatttttttg ttatgaaatt aattgaagag
      181 taattaatta gaaaaggaat gaataataat gaatatatta cattattact ttttgataaa
      241 tcaaaaataa agttataatt tttaatatta attaagaatg atgaaatatg aataaagatt
      301 ttacaaataa atcttaagct atcttattta attctaatac aggaagaagg taaatgtata
      361 ttgaaaaaat catagaaata gaagtaaaca atttaaataa atacaaaggt ttgcaaaaga
      421 agtaatataa ttatatacaa tgaggatgtg agtatgatga acagactaaa gccaagaatt
      481 ttaggtatta gtatcttgtt tattattata attattttaa catgtggagc tgttttcaag
      541 tttaaattta aattagataa taaattaaaa gaaaccacac atacatattt gtctgagttt
      601 acagaacaca atataattaa tctcaagaca agacttagtg gtcaatttga catgcttgaa
      661 tctattgcta acttcatagg aaacttgaat aatataaatg atgaaatggt gattgattta
      721 atggattctg atgtaaagcg cagttcttta attagaatga ctatctctac attagatggg
      781 gaatgttatt ctaatgatgg aattacccat aatgttcaag atagagatta ttttaaaaaa
      841 gctaaaaatg gagaaaagaa tatatcagaa cctttaaaat ctattgttaa taataaagaa
      901 ataatagttt tatctacccc agtttataaa agtgggaaaa tagttggtgt tttaagtgga
      961 atttatgatt caaaaaagtt aaatgagtta ttaggattat ctgcatttga tgaaaaagca
     1021 gatgtttttg ttgcaaagaa aaatggagat atagttgctc aaaaaacaaa taaaaataga
     1081 aagacgctat catgtatatt tcagcttttt gacaaagata attgtgatga agatgattgt
     1141 ctaaaaacta taaaagaaaa tatgaaaaat gataagtctg gatattttaa ttataactta
     1201 gataatgaaa aatttatgtt aaactatcag ccacttggag ttaatgattg gtatgttttt
     1261 tctgttgtgc caaataaaat agtatctatt cagtcagaga atatatctta tgatgtatat
     1321 atttttgcat tagaaatact actagttata ttgattttta taatatatat agcatgtatt
     1381 ataaataata acaccaaaat tattataaat gaaaaagaaa aatttaaagt actcactgat
     1441 aatatattag gaggggttaa aacctgttta aaagatgaat atatgactat gacatatgta
     1501 agtcaggggt ttttagagct tacaggttac tcttgtgaag atttaaataa aatatttaaa
     1561 aatagattta aagacatgat ttataaagat gatttagaca agtttaattg tattattcta
     1621 aatcaattag aaaaacaaga taaaattgaa gttgaatata gaattgtaag aaaagatgga
     1681 agtataattt ggattttgga gagaagtaag tctataaatg ataataaagg aagtgagtgt
     1741 attcagggag ttttaactga tataacagaa cttaagaaaa tacaagaaga attagattca
     1801 aaaagatttg aaatacaggc tatcaatgat agtattgttg gtggaatagt gataactgag
     1861 ataaatgatg attttgatag tatatattta aatgaaggtt atttaaatat gattggatat
     1921 acacgcaaac aactggaaga tgagctaaat aataaattaa tcaaacttat ttttaaagat
     1981 gatagaacag aattaattaa tagtataaac aaacaactca aattaagtga tacatttgca
     2041 tctgaacaaa gagttgaaaa aagggatggc actattatat ggattttatt aaaaggaaga
     2101 aagatgattt atgataatgg aaaatctgta ctttgttgtg ttattgtaga tattacttct
     2161 gctaaattat tagagcaaga acttaaaaag agtgaagaac gtcatgaaat cattctaaag
     2221 cagacgcaaa atattataat agaatgggat atagaaaaag ataaaatgaa tatatcacct
     2281 aattggtata ataagtttaa atatgatcct ataactgaaa acgcaacaaa aaatataatt
     2341 aaatcagtag atatatatca tgatgatatg gataagttta tttcattaat taaacttact
     2401 tcacaaggta gtgagtatga agagtgtgaa attagactta gaactagaga tactatttac
     2461 gcttggttta gtataaaggc aacaacttta tttgataata atggtaaacc ttataaagta
     2521 gtaggaagtt tgactgatat tgatgaatca aaacgagaag ctgaaaagtt gaaagaaagg
     2581 gcagaaaaag accctcttac agatttgtat aataaaaaag catcacaatc acttatagaa
     2641 gagtacataa cattggataa aaaaagaaaa ggtgctttaa tgattattga tattgatgac
     2701 tttaaaggaa taaatgataa tttaggacat ttatatgggg atgctgtatt aagtgaaatt
     2761 gcaaatgacc taataaatct atttagagca accgatatag taggaagaat tggtggagat
     2821 gagtttattg tatttataaa agatatttct gaaacaagag atattataaa taaagcagaa
     2881 gaattggtaa aaacatttga aaggtctttt ttaggtaaag gacgaaatta taaaatatca
     2941 ttaagtgtag gaattgctaa gtttccacaa gatggtatgg actatatgac actatttaga
     3001 aatgcggata tggctcttta ctcagccaaa gggaagggta agaattgtta tacattgtat
     3061 gataaaaaaa ttgataaagt ccaatatata actaatacaa gaaatgcagg agatagtgat
     3121 aatgtagaga tgtcttttaa agaacatatc acaaattata tatttgatat actatatgaa
     3181 tcaagtgata tagaagtggc agtaaattta attctaagta ttgtaggtaa acactttaat
     3241 gtgagtcgca tgtatatatt tgaaaattca gatgataatc gagtatgtaa aaatacattt
     3301 gaatggtgta acgaaggtgt aaccccggaa attaataatc ttaaaaatat ttgttacaag
     3361 gatttaggca actatctttt aaattttaat gcagatgggt tattttattg taatgatatt
     3421 gaaaatttag gtagtgatgt gaaaaaagta cttaagccac aaggcatacg ttcaatatta
     3481 caatgtaaaa ttttagaggg taatgaattt agagggttca taggatttga tgaatgttca
     3541 tataatcgta tgtggactaa tgatgaagtg aacactttga catttatatc taaaacgctc
     3601 agtatgtttt tattaaaaat gcgtattcag agtaagctag aagagtcttt aacaattcaa
     3661 aaatctgtga tggataatat ggatatatgg gcatatgttg ttgacaggaa tacctatgaa
     3721 ttactattta tcaataaaaa aatgcttgag tcagcaccaa acactcatgt aggtgattta
     3781 tgttataaag cgatatggaa taatcaagat aaaccttgta aaaaatgccc tatgatatat
     3841 ttaaaagatg gtgatgatac ttataaatca ttcatgcata ataaaaagtt tgaggtacag
     3901 gcaaatataa ctacaactac tttgaaatgg tttgatggta aagatgcatg tttaatattt
     3961 ggaagtgaaa taactagtat tgaagctgaa gaaaatactt aaaatactgt gttatatata
     4021 tacttaaaat cgcaatttga atttattaga cttaaaatgt ctatataaat catttaagtt
     4081 gtggttttaa gtatttttta tgatataatt aagcgttaag aacaaaatta aaagatactt
     4141 ttgtataaaa aaatatttgt taaatatata ttgagcaggt gataatatgg aaaataagtt
     4201 tttaccaata agcaaacaag atatgataga tagaggatgg gaagaattag attttgttct
     4261 agttacagga gatgcttatg tggaccatca tagttttgga acagcaataa tatctagagt
     4321 tttagaaagt gctgggtata aagttggaat aatagctcaa ccagactgga gaactacaga
     4381 tgattttatg aagctaggaa aacctagact tgcatttcta gttaatgcag gaaatatgga
     4441 ttcaatggtc aatcattatt ctgtaagtaa aaagcataga gaaaaggata tgtattctcc
     4501 aggtgggaaa atgggttata gaccagatag agctactata gtatattgca ataaaataag
     4561 agaagcatac agtgatgttg caatagtaat aggtggaatt gaagcgagct taagaagatt
     4621 tgcacactat gattattgga gtgataaggt tagaaagtct atgttaatag atagtggagc
     4681 agatttatta gtttatggta tgagtgaaaa gcagattgta gaagtagcca atgcacttaa
     4741 tgatggatat gacccaaaat acattagaca tattgatggg acatgctata tttcagatac
     4801 attggaagaa atatatgata aatatatatt aattccatca tataaagaaa tttgtgaaga
     4861 taaaatgaag tatgtagaag cttttaaaat tcaatatgat gagcaagacc catttagagg
     4921 taatataatt gttcaacctc atggaagtaa gtatctggtt caaaataagc cagaaaaacc
     4981 acttagtaga gaagaactag atgaagtata tggattacca tatcagaaga cataccatcc
     5041 tgtgtatgaa aaatttggag gaataccagc tatagaagaa gtaaaattta gtatagtaag
     5101 ttcaagaggc tgttttggta gttgttcatt ttgtgcaata acatttcatc aaggtagagc
     5161 agtgcaaagt agaagtgaaa aatcaattat tgatgaagca ataggaataa caaatttaga
     5221 tgattttaaa gggtatatac atgatgttgg aggtccaaca gctaatttta gaagaccagc
     5281 atgtaaaaaa caaattacta aaggtgcttg taaaaataga caatgcttat ctccatcacc
     5341 atgtaaaaat ttagatgcag accacagtga atacctacat ttacttagag ctgtaagaaa
     5401 attacctaaa ataaaaaagg tgtttgtgcg ttctggaatt agatacgatt atgtaatggc
     5461 agataagaac aataaattta ttagagagtt gatagagcat catgtaagtg gtcagttaaa
     5521 ggtagcccca gaacatatat cagaagaagt tttaaagtat atgcaaaaac cagcaggaaa
     5581 aacttatgat aaatttagac aaaagttttt tgctataaat gaagaattag gtaaaaagca
     5641 atatttgata ccctatttaa tgtctagtca ccctggttct accttaaata gcgctataga
     5701 gttagcagag tatttaagag atactcacta ccaaccagag caggttcagg atttttatcc
     5761 aactccaggg actctatcta caaccatgtt ttatacaggt attgacccgc ttacaatgaa
     5821 gccagtttat gttcctaaat caaaacgtga caaggcaatg caaagggctt tattacaata
     5881 tagagcacct agaaattatg atttggtata ctctgcgtta gttgaagcag gaagagaaga
     5941 cttaattggt tttggacata gatgtcttat aaagccaaaa aatgaaaagc cttattttaa
     6001 tagaaataat tctaaaaaaa atgtatctaa aggaacaaat aaaaacaaaa aaactaatac
     6061 aaataacaga agtaataaaa atcaacaaaa aagttcaact aaaaaaaaga aaaaacatta
     6121 aagtataaat aaaaatactt aaaaaagaag gattattcga taaattaaca gaaattagta
     6181 taaataaata taattatttt aatgacgtta cctttgggag gaagagatga aaaagtatat
     6241 ttctataata ttattagtgg tgttgactat ggttgttttg gtaggatgtt caccaggaaa
     6301 agataaccct aaaaataagg agctatcagt tgtcaaacaa gtaaaagtag ctgttccaga
     6361 tggactacca gcagtggcaa tagctaaact tgcaaatgaa aatccagaga ttaaagaagg
     6421 atatgaaaca gtgtatagca ttgaaaagac acctgaagcg atttccacta gagtgatgaa
     6481 aaaagatgca gatatagcta tagttccttc aaacatggct gcaatagcgt ataataaaac
     6541 ttcatcatat aatattgttg gaactgtagg aatgggttca ctttatttgg tgtcaacaga
     6601 aaatataaaa gattattctg atttagttgg taaagaagtt ggatgtactg gaaaaggact
     6661 tactccagac ataactataa aaagtctttt gttacaaaag gatataaatt attcagatat
     6721 aaaatttaat tatgtaaatt cagcaagtga actggtacca ttattggcta ctggtaaagt
     6781 taaaacaggt attgttccag aacctgcact tagtgctttg atgtctaaaa atccagacat
     6841 aaaaattata aaaagtttaa atgactcatg gaaggaagta agtggttcaa aagatggtta
     6901 tcctcaatct actttaattg taaagtctga atttttaaga gataataaag attttgttga
     6961 ttcttttgta ggtcaattat caaatagtat agattgggca aacaaaaatc ctgaagaatt
     7021 aggtgcatat tctgaaaaaa taaaaatatc tactgaatca aagataatag gaaaatctct
     7081 tgaaagagct aatttgaaat atattccagt taaggacatg attaaagatt ataaaaatta
     7141 ctatgagaaa ttagctaatt ttgatgataa gacattagga ggcaaagtac cagatgaagc
     7201 aatatacttt gttgagaaat aaaaaaaata aagaacaatt tatagataaa atggaggtaa
     7261 cactttcttg tgttatcctc ttatttttat ggcaaattat tgctttaaaa attgataatg
     7321 atattttttt accaacagta ggtcaagtat ttaatagtat aaaagagatt atgctaaatt
     7381 ctagtttcta tatagatata ctttactcta tggggagatg tttttttagt tttttactgg
     7441 ctatgatttt tgctattata ctttcaatag tgtcttattt aaatagattt tttagaaact
     7501 tattaaagcc aatcaatgct ttgacacgtt caataccaac tatgatattg gtagtacttg
     7561 cacttatttg gtttgaaaag gatagtaccc cttttatagt tggatttact atagtttttc
     7621 ctatattgta tgataacgtt ttgggcgcta tattgaatat agacaagaac ttattagaaa
     7681 tggctaatgt gtataaaata aggtttatag ataaggtgtt aaaaatttat ttaccagcca
     7741 taaaatttca aattatatct atactagtat caacattctc tttaagtttg aaagttgcta
     7801 tagcaggaga ggtatatagt caacctacat atggtattgg aactatgata cagactgaaa
     7861 aaattaactt taacacatct ggaatatttg catggataat tattgttctt ttaatatctg
     7921 ctattttaca aatagctcaa aagtttttag caaggagagc ttttttatgg aaaagataaa
     7981 gttgagtatt gaaaatataa ataaaagata tgatagtcgt attatattta gagattttaa
     8041 tattgatttt tatgtaaatg aggtaaattg tatccttgga aaatctggtt gtggaaaaac
     8101 tacactcttg aacataataa gtgggattat taaaaatgac accaacaatc taaatatcaa
     8161 agaaaattta aatagagtag gaaataagct tgaagctagt tacatatttc aagatgatag
     8221 acttatagac tggttaacag tagaagaaaa tataaagata gttgtaaata aatactataa
     8281 taaaactcaa ttaaataaaa tttgtgatga atacttggaa ttggttggaa ttagtgatta
     8341 taaaaaattc tatcctcaaa tgcttagtgg aggtattaga caaagagtaa atattgctag
     8401 agcttttata tatccatcaa aaaacattat aatggatgaa ccttttaaat ctattgatgc
     8461 aaagaataca cagcttataa tggataattt cagaaatata ttaagaaaag aaaaaagaac
     8521 tgtgttattt gtaactcata atattgagga agcattgttt ttagcagata ggatatttat
     8581 tttaggagac tctccaatta gaataaaaaa aatattaaaa aattctaagg aattggaaaa
     8641 aaatgaagtt ttgaagttga tatagagtta taataatact gtcgttttaa aatatatttg
     8701 gttaaaatct ataagactat attaaaatag tacagaatat tcaaaactgt gtataatgtt
     8761 cgtattttat aaaaaggaag tgaatgtatg gttaagacta atgctatgag aatattagat
     8821 tcaaataaga ttgattataa agtaatgtct tatgaagtga aaagtgaaca tgtggatggt
     8881 gttgaggtgg cacatgatat aggaagagat gtaaatgaag tgtataagac attagtaact
     8941 caaggagtta gtaagaatat atatgtatat gtaataccag tacatgaaaa cttagactta
     9001 aaaaaggctg caaaagtagc taaagagaaa agtgtagaga tgattcatgt aaaagatata
     9061 aataagctta caggttatat tagaggcgga tgttctccta taggtatgaa aaagctttat
     9121 aaaacttttg taaatgaaag tgcaaagaat ttagatacaa ttattgtgag tgcaggaaaa
     9181 ataggatatc aaatagaact atctccattt gatttacaaa gacttataaa agtagaattt
     9241 gtagatgtaa taaaaaaata agaattacat ataaaatata gagcttatat tctcaataat
     9301 aggtgttgta atattaataa aatgaataat aattttaaaa taaatattca gttacttatg
     9361 tgtaattggt ataaaaatat tgagaaattt taaaaacaat ggtaaagtgt aagtataatc
     9421 acgaatattt tttataaagt aatggaggga tgttcgcttg agaaaaataa aatctgaaca
     9481 aatcgtcgag caggtaaaaa aactttgtat agaagcgagc ctatatttag gagaagatgt
     9541 tttaagttgt ataaaagaaa aagcgaaaag cgaaaagagt gaagttggaa aaaatatatt
     9601 gaatatatta gttgaaaatg ctgaaatagc taaagaaaaa aatataccaa tatgccaaga
     9661 tactggtatg gctgtatttt ttgttgaaat aggacaagaa gttttaattg aaggagacac
     9721 acttactgat gctataaatg agggagtaag acaagggtat gaagaaggct acttaagaaa
     9781 atctgttgta agtccaatta acagagtaaa tacaaaagat aatacacctg ctgttattca
     9841 ttatgatatg gtaaaaggtg ataaaattaa aatagaattt gcagctaagg gatttggaag
     9901 cgaaaatatg agtaagatga aaatgttaaa gccatcagat ggattggaag gaattaaaaa
     9961 attcataata gatacagttt cagaagctgg acctaaccca tgtcctccta tggtaattgg
    10021 agttggtata ggtgggactg tggacaaatg tgctcaaata gctaaaaagg cactttttag
    10081 agaactaggt gaatttaata aggacgaaaa tatagcaaaa cttgaaagtg aactattaac
    10141 agctattaat aaacttggta taggacctca aggcttaggt ggtactacaa cagctttggg
    10201 attaaacata gagacttttc ctacacacat agcaggtcta cctgttgttg taaatataaa
    10261 ctgccatgca tcaagacata agaaggtagt aatttaggag gaaaataaaa tgataaaaat
    10321 aactacacct gtaaatgaaa ttgatatagc aaaattaaat tgtggagata caattagttt
    10381 gagtggtata ctttatacag caagagatgc tgctcataaa agattgatag attgtataaa
    10441 taaaggtgaa gaattaccat ttgacgtata tggtcaagga atatattatg taggacctac
    10501 tcctacaaag ccaggagaag ttataggtgc tgcaggtcca acgacgagtt atagaatgga
    10561 tgatttgact atacctcttt tagaaagagg tcttagattg atgataggca agggaaaaag
    10621 aagtgatgaa gttatagaag gtatgcaaaa atacggagca gtttatcttg ctgcaatagg
    10681 aggagctgga gcgtatattt caaattcaat aaaatcatgt gaaattattg catatgaaga
    10741 tttaggagct gaagctataa gaaagattgt agtagaagac cttaaactta cagtagcaat
    10801 agatagctat ggaaataata tatatgagca aggtcgagca atttatgaat gtaaataatg
    10861 tttagaaata aatatgaata tcaaaattaa aaatagttgt gtatatttta aggaggaaaa
    10921 ttgatgtcta aggattatgc aaaattggca ttagaaatgc atgaaatcaa caaagggaaa
    10981 gtaagtgtag aaagcaaggt agaagttaaa actaaggatg atttatcaac agcatataca
    11041 ccaggggttg ctgaaccttg tttaaaaata catgaaaatc aagatgatgt ttatagatac
    11101 acttctaaag ggaatctagt agcagtagtt agtgatggaa gtgctgtact tggattaggt
    11161 aacattggtg ctgaagcatc tatacctgtt atggaaggta aagctatatt atttaaacaa
    11221 tttgcagatg tagacgcttt tccaatatgt ttaaagacta atgatgtaga tgagatagtt
    11281 aaatctgtag agttgatgga gcctgtattt ggaggtataa atttggaaga catatcttct
    11341 ccaagatgtt ttgagataga agagagatta aaaaaatctt taagtatacc tgtttttcat
    11401 gatgaccaac atgggacagc aataatagtt gcagccgcca taataaactc aataaagtta
    11461 attgaaaata aaaaaataga agatttagaa atagttataa acggagcagg agctgctggt
    11521 atagccatag caaagatact acttaatatg aatgttaaaa atataatctt atgtgataga
    11581 agtggagcat tggaagctag tatagaaaat ctaaactatg ttcaaaaaga aatgttaaaa
    11641 gtaacaaata taagaaatga aaaaggatct ttaaaagata ttataaaagg aaaagatgta
    11701 tttattggtg tttcaggtcc aggagctgtt acaaaggaaa tggttgaaag tatgtctgag
    11761 aagccaataa tattggcaat ggcaaatcct actccagaga taatgccaga agaagcaaaa
    11821 ttaggtggag catttataat gggaacaggt cgttcagact tccctaatca agtcaataat
    11881 gtactggctt ttcctggaat atttagaggt gcacttgatg ttaaggctaa agagataaat
    11941 gaagaaatga agatagctgc tgcatatgca attgctaata caataagtga tgaagaaata
    12001 tgcccagagt atatattacc agatgtattt aataagaatg tagtaaaaaa tgttgctaag
    12061 gcagttaaag aagcagcgat aaaaaccaaa gtaaatagaa tataaatttt tatatgttca
    12121 tatatcctta tattatcggg tatatgggca tttttattat aggtttatac tcatatatcc
    12181 ttacttttat atacatatct ttatgattaa aggtgttaga aaatgtagta aattttatac
    12241 tatcagactc tatctttatt actttagtag atacatggtt gtaaaggttt atagaaaaaa
    12301 atataggaag gcagattttt attgttgcgt atatatgaga atgatataat atgaatatta
    12361 taaattaata aatttaaatt tatggaggta caagagatga tggaatataa agttaatgac
    12421 caagaactta atgcttcaat gtttatccca ttcgtcaaca ggatatggcc aggagattat
    12481 gatatggata aaacacagac tgcattatca aaaactttga atataactgc ttatgatgat
    12541 aaagtgcttg taggatgtct gcgagttctt tcagatggtt attattttgg aacaattaca
    12601 gaattgcttg ttcttccaga gtatcagaaa caaggcattg gtagtaagct tttccagctt
    12661 gctaaagaga acaccccaac tatgctatat tttggtgcac agccaggagt agaagcgttc
    12721 tatgaaaaaa atgggtgcca aagaagtctg caatcctaca taataaaaaa gaaagatagt
    12781 tattaaagtt ccagctttca ataatcttaa aagtacaata ttttagtgga atcatttcat
    12841 tttttattat taatatgaca taaacatgtc atattagtat tgatatactt ttaatatggt
    12901 taagagccaa agaaaaatat aaggagtgat ttaaaatgga agaaactaaa ttttgccaat
    12961 gctgtgcaat gccaatggga caaactgatg aattatatgg gacaaataaa gatggaagta
    13021 aaagtactga ttattgtagt tattgtttta aagatggtga gtttatagct gatataagta
    13081 tggaagagat gatagaagtt tgtatccctc atatgcttca aagtaataag gatatgactg
    13141 aagatgaagc aagaacaatg atgaacaatt tctttccaac attaaaacgc tggaaataat
    13201 tttatgcaaa attagttata tgcaaaacat gaaatatggt gttgagaata aggggtggtg
    13261 tgctttatag cataccacct gttttgttac ttggagttca gttattttcc taaatatttt
    13321 aaatatacta ttttagataa gttccctctt catcttgata aattaatcct tttttcataa
    13381 gcactccaag agctcgttta aaatttttct tacttgaatt aaataatata gaaatatctt
    13441 tagggtcaga tttatcatta aatctcatat atccatcaga accttctaaa taacttaaaa
    13501 tcttattttc taaagtatca agttcatcct ttctatttcc tctaggagaa agaccaagtt
    13561 ttccatcttc atatattttt atgacatgta aattttcaag aacatcacca gtttttagtt
    13621 cagtaaagta ctcattatga agtattacac cagcatattt attgtctaca catatcattg
    13681 cagaattatt agtttggaat ccatatacaa ctccagttac aatatctcct acattgtaag
    13741 tatggtctgt taataaatat gaatctatat ctgtagtagc agcaattctt ttgcttttgt
    13801 ctaaatatat ataaaataaa tatttttcgt ctctaaatag tggataagtc ttagctttaa
    13861 aaggaactaa tatgtcttta ggaagtccca tatctataaa agtaccaatg tctgtattat
    13921 caactacttt taaatgtgct acatccccaa ccttagctaa aggcggtatt aaagttgcag
    13981 cagttctgtc atcagaatct ttaaatatga aagaatttac ttcatcacct atgtttattt
    14041 cattttttcc gattaatcta ttatgaagaa gtatatcgtc ttttgtgtta ttagtttgtc
    14101 catccaaaaa atatccaaat tcagtttttc tttttactgt aagtttatta aaatcaccta
    14161 tgtttatcaa attaaaatca tcctctcatt ttatatttat aatttagcca taatatactt
    14221 atgtagtagt ttgtcacagt atctatatta gtattagtga aatttacaat aaataatata
    14281 gttatttatg tatttttcaa ttctctagct tcttatatag tataaactcc aatttctttt
    14341 ttgtctttag gttttattaa aatttttaca aaataagtta aaaagtattg aaataaaatt
    14401 tcttttaaag tataattggt atataccaaa attggtatat accatatcga aaagtggtga
    14461 ctatatgaaa atagtaaata aatctagtaa tataccattg catactcaat taagttcaat
    14521 aataagagag atgatagaaa ctggtgagct taaagagggc gatgcaataa tgccagaaag
    14581 agaactttgc aacatacaaa atgtaagtcg tatgacagta aataaaacca ttgttggatt
    14641 agttacagaa ggacttcttt atagggtaca aggtaaaggg acattcgttg caaagcaaaa
    14701 aaagaagtat cagttttcaa atgtaaaagg ttttactgat gttatgaaag aaaagggagt
    14761 aaacataaaa acgtatatat tatcctttga gatggaacta ccagatgatt tagttaaaag
    14821 aaagcttgga ataagtgata atactacaaa tatatataag attgtcagac ttagatatac
    14881 tgatggagag ccatttggat tagaaatagt atatctatca gaagaaatgt gtaagggtct
    14941 aacaaaaggg atattggata attcttcatt atatagggtt ttaaatgaaa aatatggcta
    15001 taagatacaa aaagctgaac aggtaatgga gccagtaata ctttcagatg aagaaagtaa
    15061 gcttcttgaa acagatgaag gtgctttagc tcttaaactt catagaaatt cctataatag
    15121 agaaggtagc cctatagaat ataccatatc aatatttaga acagataaat atcaatatga
    15181 aatagtattg agtgagtagg tgaataatat gaaatgttta attaatggaa agataatatt
    15241 aaaaaatcaa atcttagaaa ataaagtatt agtatttgat gaaaaaataa ttgatatagc
    15301 tgatagtgta ccaaaagatt gtgaagttat agatgctgat ggaaaatata tatctccagg
    15361 gcttattgat attcatatac atggaaacat gggaaaagat acaatggatt cgactgatga
    15421 atctattgaa acaatttcaa aatcaattat gagacatgga gtaacatctt ttctgccaac
    15481 tacaatgact atggataaag aacatgttta tgatgcactt gaagttatta aaaaagccca
    15541 aaatagaaag cttgaagggg cacaagtatt aggagcacat ttagaaggac cttttataaa
    15601 tgagaattat aagggagcac aaaatgaaaa atttataata aattcaaaat acgaatttat
    15661 aaaagaatat aaagatgtta taaaagttat aacttatgct ccagaaaaag atattgattt
    15721 tgattttact agagaaataa aaagatgtac agatatagtt ttatctattg gtcatagtaa
    15781 tgcaaattat gaccaagcta aagaagctat aaatttagga gtaactaatg taactcacat
    15841 gttcaatgca atgactggtt taaaccatag agacccaggc gttgttggtg cagcacttac
    15901 aactaatgtg tacagtgagt taatagcaga tacaatccat ataaataaag atttatttca
    15961 atttatacta aataataaag gaaaagaaag actgatttta ataacagatt ctatagaagc
    16021 tggtggtctt gaagatggca attattctct tggaggtcag agagtcatag ttaagggtaa
    16081 tgaagctaga cttgaaaatg gagcattagc tggaagtgtg ttgtctttaa ataaaatggt
    16141 atttaacttc ttagataata caaaccttaa agtgaatgaa gcaattaatt tagcttcttt
    16201 aaatccagca acatctttgg gaataaatga caaaaaagga agcttagaaa taggtaagga
    16261 tgcagatata gctgtatttg atgagaattt agattgtaaa atgacacttt gcttggggga
    16321 cgtagtatat aaaaatatat agtatacaaa acaaacctta aagacagtaa aaacaatata
    16381 aaaaataata aattaaactt acattagtaa aagtagtagt taaaatttag gaggaataag
    16441 atgagagtat tagtgtgtaa agattatgat ggaatgagta aaaaagccgc tgaaatgata
    16501 gccgctcaaa tagttttaaa accaaattca atactgggac tagctacagg aagtacacca
    16561 gtaggtatgt atagagattt agtaaaaaaa tacaatgata atatagtaga tttttcagat
    16621 gtgatgagct ttaatttaga tgaatattat aagttaccaa tatctaatga ccaaagctat
    16681 gattatttta tgaaagagaa tctatttaat catgtaaaca taaagccaga aaatactcat
    16741 ctaccaaatg gaatggctga tgatattgaa aaagagtgta tgaactatga agcttctata
    16801 gatgcagctg gtggtataga tgtacaagta cttggaatag gtcgtaatgc tcatataggt
    16861 tttaatgaac ctgatactaa atttgcaaaa agaactcatg tagttgaact tacagagtct
    16921 acaatagaag ctaatgcaag attctttaaa tcaagagaag atgttcctaa aaaagctgta
    16981 agtatgggaa taggttcaat attgaagtct aagaaaatat tgcttttagc ttcaggagaa
    17041 gaaaaagctg atgcagtata taatactgtt tatggagata taactccaga agttcctggt
    17101 tctatacttc aacttcataa agacactata gttatagtag atgaagcagc agcaagtaaa
    17161 ttgaatccaa aagattataa attagtataa gaatagaatg tagtttaagt aaaaaatagc
    17221 tatcattgaa taatcaaatt tatttaatga tagctatttt tatttaaatt ttttacttct
    17281 ttttatttaa attagttatt attgtttaaa ttacttgctt attacttttt acgaaaactc
    17341 gttatcaaga agtatccgaa taagatgtta aaaattatta tgtttagtgg gattctatca
    17401 agcataataa aattacctat aattgggata ttaccaactg gaaacataaa gaataataca
    17461 ggcatcagtg atagtaaaaa agatggaaaa caaagaagaa gtaatcttgg aatatcaata
    17521 taccaactac catccttttt gtattctcta atcaataatt cagttcctag taataaacca
    17581 ataccaccag aggaaattaa attaataaaa atgtatcttt taaagtcttg catataacca
    17641 gtgtaaaatt gagtatagaa atcataattt aatttaacgg ctaaaaaata cataagcaat
    17701 agaatgatta aaaataaaag atatctaaga gcttttttca ttttaaattc tcccttcaga
    17761 aatactttat ttagttttat tttgttggaa tctgatttta tcatttagtt taagaaatcc
    17821 ataatattag tgaagaatga aataagtatt atatatgaat aaatattttt agaattaagg
    17881 tgaattgtag tgcttaatat aactataata ttaattgttt gaatattcaa taaaaagttt
    17941 gaaaaatatc aattctgata taaactgaat aaatacagtt gaatattaaa ttattatttt
    18001 atcaaaaata tgcaaagtac tacaccttca aatatcacct aaagtaatta aaaggcaatt
    18061 aaagtgaagt agttcaagta tttctaaaat aagtttaata aattctataa taatttattt
    18121 tttgccttaa aattgcctta aaatccaaac aattttaaaa ctaatgtact ataaaaagct
    18181 ggtataattt aaatatagta aaaaataaga tttatcttat ctattgggat ttaattattt
    18241 aatcaatata tttataccat ttaatttaaa taaaaagtct attaaggagt gagcttatga
    18301 gtaagttaat ttatatagca gatgatgaag ataatataag aaatttggta aagacattct
    18361 taaaaaatga aggtcatgat gttatggatt ttaaaacggg tgatgaactt ttagaacaat
    18421 ttaatataaa ggagtgtgac ttagtaatac tagatataat gatgcctggc tcaagtggtt
    18481 ttgaagtatg tacaaaactt cgtgagaaaa gtacagtccc aataatcatg cttactgcaa
    18541 gagatacaga tatagattat attacaggga taaccttagg tagtgatgat tattttacaa
    18601 aaccatttag cccaatgtct ttggttatga gagtaaaatc tatatttaga aggatagagt
    18661 ttgaaaagaa acaaaattat gataaatata gtaactcgat agatatggaa ttaaaatttg
    18721 gtgatgtaat aataaataaa aagaataaaa tcgttacaag taaaaatgta aatatagacc
    18781 ttacaccaaa tgaatataac ctattgactt atttgtttga aaatatagat agagcagttt
    18841 ccagagatga attattaaac aaaatatggg gatacgatat agaagttgag acaagggctg
    18901 ctgatgatac agtgaagaga ttacgtaaaa aaattttaaa tacaaatatt ttaatagaaa
    18961 ctgtatgggg gtttggattt aggttgaagg agaaaagtta agatgaagaa tggaaatgac
    19021 aagaatagaa ttggaaagat taaatccaaa tttaaattaa agttctcaaa gaaaaatata
    19081 agcataaaaa ctaggatttt gttgagtata ctttgtttga taattatagt atttatgata
    19141 atattagtat cttttaatgt atttcttgat acatatataa aaacaactgc gaatgaagaa
    19201 ttgacaaagt ctacagaaat agtagaacat atggatagta attttagacc tattaagcca
    19261 ccacaagatg atggaaagct tcctcccaaa gtattatcta attttatgag aaatgtacaa
    19321 gataaagtta ggatggcaga aacacaatca gatgctgatg ctatggtagt tgattctaag
    19381 tataacctga tatttccaac aagagaggat gatttcttaa aaaatgttga tgagatggag
    19441 ctgattaggg agtgtattca aaatgaaaaa ttagatttaa attcagatga aaatacacgg
    19501 atatctacca gaaataagga ttattatatt tcaactgtaa aaattactag tatatatggt
    19561 gaacaagaca agtatcttat actttttata gacatatcaa aaactctaaa tctagcacaa
    19621 aagataaata ttgtattaat atctgtaatg tgttttgctg gaatattagc aatatttaca
    19681 gctgtgattt tatctgagaa aattgctaaa ccgataaaag agttgtgtga gtttgcaaaa
    19741 aaaaatgggt caaggagatt tcaaaagaac ctactttgac ttttcagata aagaattagt
    19801 agagctctca actgttatga ataagagtgc tgagtatctg gataagtatg ataatgaaca
    19861 aaaaatattt tttcaaaatg catctcatga attaaggaca ccacttatgt ctattaaagg
    19921 ttatgcagaa gctataaaat ataatgttat agatagtaaa catgcaagtg atataattct
    19981 tgaagaaagt gataggttaa gtgatatggt tgaagattta ttatacattt ctaaaataga
    20041 taatataact aaagattttg aacttgtaga atgtgattta agagaagtac tttcaaattg
    20101 tggagctagg caaaatgtaa gagctataaa taaggggata aaatttattt atgaatttga
    20161 tgaagaaatg gttttatttg aatgtgatga aaaaaacatt tccaaagcat ttatgaatct
    20221 tatagaaaat gctttgagat acgctaagag tgaaataaaa atagtgtgta agtataatca
    20281 aaaaaatata gttgtgataa tagaagatga tggaattgga atcaagaaag aagatttacc
    20341 tcatgttttt gaaagattct ataagggagt aggaggaaat catggaattg gattatcaat
    20401 agttaaatct attgtaaata agcatggtgg gcgtatatac gtagaaaatg gcaaaaaagg
    20461 agctaaattt actatattat ttaaattgta aaaaaattag agaaaatata gagatgtttg
    20521 aagttgtttt ttatatatat ctgttgtata ctgttgaaaa aagaacaata ttaagctgac
    20581 atatattacg atagttgaca tttaaagtaa atgcttaaat atagatacga aaggaaaagt
    20641 aaaatctgaa gtgtatttag gtttaagtaa gcttcttatt ttataaaaaa tatgtatgaa
    20701 agaacagctg atttttaata ttacaaattt agtaacggtt gtatttgaag cttttgtcat
    20761 ccatatgttt ttatcagact ttttaggcca gaaagaaggg tatataaaag ttgtaagata
    20821 tgctaaactg ggttttataa tatgtttagg attctgtaat ttaataactt taaaccctaa
    20881 aatcacaatg cctttaattt tcatccttat tttttcaaca tcatttttat ataaaggaaa
    20941 tttaaagaca cgattgttta ctactgtttt attaagtata ttctttatac tgtcagaaat
    21001 tgtagttaca agtatttttg ttttatttgt aaaagaaggc tttgaaataa tgcttgaaaa
    21061 taatagtata agagtattgg cgacaatttt atctaaaatt gtctttttgt tgacttgtaa
    21121 aattatttgt ctatttaaaa aggatgtaca tttagatatg cccataaagt attggctccc
    21181 tttattttta atacctatat ttagtttatt tctgtctgtt tctatctttg atgtaagtaa
    21241 attttttagt cttgaaagtt taaaatttct aagcttaata tctagtgttg gtattttata
    21301 tattaatttt attgtctttt atttatttaa atttattata gataaaacta aactatctat
    21361 gaaatatgaa ctacttgaaa aagaaataat tcataaggaa gaattaagac ttagtaatga
    21421 gtgttataaa attattgttg aacagactga ttctgtcgtt ttcgaatgga atatcaaaga
    21481 aaataaatca tttgtgtcgc aggcttggac tgaaaaattt ggatataaca atgcatgtaa
    21541 gaatattttt aaagaaatta aagataaaga cttagttcat tctgaagata aagctatatt
    21601 tgaaggtttt cttgaaagta ttaaaaaaac gaatatgcac aatcaagcag tatatcgttt
    21661 aaaaaaatct aatggtgaat atatttggtg tagaacatca attacaagca tttataatga
    21721 tgaaaatgaa cttttaagag ttgtcggagt aattgtagat gtagatagtg atataaaaaa
    21781 atatgaagag ttaagaacta gagcagaaag tgactcattg accaatatat acaataaagg
    21841 tacatttgaa aaattagtgg aagaaactat agttatgaat acaggtgata aaaaagatgc
    21901 attattcatt attgatttgg atgattttaa agaaataaat gataattttg gtcatccatt
    21961 tggtgatttt gtactaaaaa catttgctga taagatacaa gctagttttg gtagtaaaga
    22021 cttagtcgga agaattggtg gagatgaatt tgttgtatat atgcaagatt atgttacaga
    22081 agtaaatttg cataaaaaag ctaaagaatt aaatagagta ctttcggata attacactga
    22141 tttgagtttt agttttgatg cttctgtcag tataggtatt gcaaggtatc ctcaagatgg
    22201 aacttcattt tttgaattgt ttaaaaatgc agatagagca ctttatagca taaaagcatc
    22261 aggtaaaaat tcatattgtt tatttgaaga agaactatat gtacagtgaa tttgaattta
    22321 gattttatgt gagagtaaga tttatatata cttgtggctg tctgatttat aaaatatgtt
    22381 actttgtata tttttatatg tttcagtaag gctaattaac ataagcaaag gtgtaagtaa
    22441 atttatatta atttaagttt acttacacct ttataaaaat acaaataata gattcattta
    22501 cattcttaaa tgattaaagc tctttacctt ctaaacatgc ataacatatc gttataattc
    22561 cagtaaataa gactaaaata cccattccta agattacagt ttcatcatct attactccaa
    22621 atgtttttaa agtaacttat ttcgctttgt atcataataa tttatctcct tttacatttt
    22681 aacttctgct gagatttgag ttagatattc gttagaatct cgcacactta tatcatatag
    22741 aagatattct tcataaacaa aatccccaat acgtaaatta ttctgattaa aaaaatttaa
    22801 taacttttca taagtcttgt aaatagtttc ataactccct ttatgataag cagttacata
    22861 aagtcccttt ggtctgattg atacaggata tttcttgtac tctttattaa cttttgtaaa
    22921 taaatatgaa tatgattcaa agtctttatt aattatatct tcacctttaa tgattgagcc
    22981 aatcgtacca taatcactca attcatagtt gtccataaaa ttaatacatt catataaaaa
    23041 attttcttcc tcatctccta aaaactgttc tttatatgta acaggtgttt tgaccaagta
    23101 ctcttcttca tgttctttta aagtaatagt attcgcatct atattacaag catttttagt
    23161 gaatgaaata gtagattcca ttagagcttg aatattattt agtttttcaa tttcattttt
    23221 aatatcaatg gttttctttt ctaaaagctc aattagtaaa ttaggtgttc ttttgtctat
    23281 ataagcttta atttctttta aaggcatttt tacttcccta agtgaagaaa ttataccaaa
    23341 aatgctaagt tgatggtatg agtagtatct atatccattt tctttcttta attctggtga
    23401 gaaaagacct atatcatcat aatggaaaag tgttttttta ttgattccac aaatctttgc
    23461 aaattctcca gttgtaaaat aattttttga aacttgactc ataattataa ttcctccttg
    23521 actatcctgt tacagtatag tttatcatag tattttgtaa aggagtgtga ttatatgaaa
    23581 aaattaattc attttttaaa accatataga gttttaattg ttgtagtttt gatatttacg
    23641 tttttacaaa cacttggaac tttgtatata ccaacactta cagcaaatat agtaaacaat
    23701 ggtgtagtaa agggagatat agattatatt gtaaaaacag gtttaatgat gatgatagta
    23761 gctggtataa cagctttatc agctgtgtta gtttgtaaag tatcagcaaa tctttcatct
    23821 ggattttgta gagatattag agaagcagta tttataaaat cacaagattt atcaataaat
    23881 gattttaata atataggtac agcatcaatg attactagga gtactagtga tattacttta
    23941 ataggtcagt ctgtgtttat gtttattcaa ttagtattac cagcaccaat tataactgtt
    24001 tctggtctat tcttagcata ttctatagat aaagcaatga caattattat tgttgtagta
    24061 atgtttttat tcatgctttc agcattttta gttggtaaaa agcttataaa gttgtttaaa
    24121 atgatgcaaa taaagatgga caatatgaat agggtgttac gtgaggtagt aactggagta
    24181 agagttataa gagcttttaa taggagtcgt tttgaaaaaa agagatttga tagaactgca
    24241 atagattatt ctgaaacagc aatttcaata aataaaatat ttgcagtact tatgcctatt
    24301 gtaatgttaa taatgaattt aggtatagta agtattattt ggtttggtgg gatgagagtc
    24361 agtaatggaa atatggaaat aggtcatata atggcacttg ttgaatattg tatcttaatt
    24421 ttattctatt taatcatggg agtaatggta tttatgtaca tacctagagc aggtgcatgt
    24481 gcagatagag taaatcagat attagatata gaacctgaaa ttgtagatgg aaatggtcat
    24541 aaagatactg tctcagagag aggacattta gtatttaaaa atgtaaactt ttcatatgca
    24601 caatcagaag aacctgtgtt aaataatata acatttgaag caaaatctgg agaagtaact
    24661 gcaattatag gaagcactgg ctcaggcaaa tctactattg caaatataat accacgtttt
    24721 tttgaaattc aatctggaga aatatctata aatggtcagg atattaagaa gattcctcaa
    24781 aaagaactta gagataagat tggatttgta ccacaaaaag cttttttatt tagtggaaca
    24841 atagaagaaa atataaggta tggaaaagaa gatgcaagta ttgaagaagt aaagcatgct
    24901 gcaagtatag ctcaagctga tgaatttatt tatgatatgg aagacaagta tgactcattt
    24961 gtagcacaag gtggaaataa tttgtcaggt ggtcaaaaac agagaatatc cattgcaaga
    25021 gcgttagtta gaaagcctga agtatatgtc tttgatgata gtttttctgc attagatttt
    25081 aaaacagata aaagacttag aaaagcgttg aaaaatgaaa tcaaagattc atcagctata
    25141 attatagcac aacgtataag tacaatcatg gatgctaatc agattatagt tttaaatgat
    25201 ggaaaaattg taggtattgg aaaacataaa gatttacttg aaaattgtga agtttataag
    25261 caaattgcgg attcacaact tagtaaagaa gaacttgcat aaaatgaaga attaatctga
    25321 tatttggagg tgtatgatat gagtgaaaaa agaatagatg aacaagatat agaagtactt
    25381 agttttgaag atggcatgtc agcagaaaaa gctaaggatg caaaaaaaac tactaagaga
    25441 ttattaaaat atatggcaaa acaaaagttt aaaatattaa ttatttttat ttcagtattg
    25501 ataagttcag cgcttacagt tttagcacct atggttatgg gaaaagctat tgaccaacta
    25561 tttaatggaa taaaaactgc agtccaaaca ggtacaaaat tcagtgtgaa ttttagtact
    25621 atggggggga tagtatcaat acttctaggg ttgtacttaa ttagtgcagt atttatatat
    25681 attcaacagt atattatgtc aggagttgca caaaatctag ttcttagcat gagaaaagat
    25741 ttaagtgata aactcaataa acttcctctt aagtactatg attctcataa aaagggggaa
    25801 acacttagta tagtaacaaa tgatttagaa aaagtagcag atagtttaca agaaggatta
    25861 atgcaactta ttacagcagt agttacagta gttggttcta ttgtaatgat gataagtata
    25921 agtgtaccac ttacaatagt atcagctata acattacttg tttcattggg tattactgtt
    25981 gtaattgcaa gaaaatcaca agaaagattc tctgaaaatc aaaaggcact aggagagtta
    26041 aatagcaata tagaagagat atttactggt caaatagtgg ttaaagcatt tagtaaagaa
    26101 aaggatacta taagaaactt taaaatatta aatcaaaatc tttataatgc aagtagaaaa
    26161 gcacagtttt cgtcatatgc aatatctcca attattagat ttataaacct aattggctat
    26221 gttattatag cagttgtagg tgggatattt gcatcaactg gagcaatgac tcttggtagt
    26281 atacaagcgt ttattcaata tgtaaatcaa gcatcagagc ctactacaga aatatcttat
    26341 attgtaaata tgcttcaagc agcaatagca tctgcagaga gagtttttac agttatggac
    26401 gaggtggaag agataaagga taaagaatct tcaaaggtta ttagcatgcc taaaggtaaa
    26461 gtacaatttg agcatgttaa atttggatat agtgatgatt ttattcttat gaaagatatt
    26521 aatatcaatc taaatgcagg agataagatt gcaattgttg gacctacagg agctggaaag
    26581 acaactcttg taaatttact tatgagattt tatgagatac aaggtggaag aattactatt
    26641 gatggtgtta atataaaaga tttaaagcgt ggagaactta gaactatgtt tggtatggtt
    26701 cttcaagata catggctgtt taatggaagt ataaaagaaa atattgcata tagtaagtca
    26761 gatgccacaa tggatgaaat tgtaagagca gcaaaatcag caagagtaga ccattttata
    26821 aggactttac cacaagggta tgacactata ttgactgagg atgcttctaa tctatctcaa
    26881 ggtcaaaagc aacttctaac aattgccagg gcaatacttt cagacccatc agtattgatt
    26941 cttgatgaag caacatctag tgtagatact agaacagagg tagaaattca aaaggcaatg
    27001 aataacttga tgaagggaag aactagtttt gttattgcac atagattatc aactattcga
    27061 gatgctgatt taatattagt aatgaaagaa ggaactatta ttgaacaagg aagccataag
    27121 gaacttattg aaaagaaagg attctatgaa gaactttata acagtcaatt tacaagtgaa
    27181 tatgatgaag atgttgtatg attatcaagt tttaggcaac taaatgattg ataaatatta
    27241 agttaaatat agtaacatgt aaggttatat ggaataagag tatttctcta tttcatataa
    27301 ccttttttat ttatcaaaat aagataaaat ttcctttcta aattagattg aagaatgtat
    27361 ttatcaatat aaaagtaaaa taatcattat tattagtgaa gtaaatattg tttgccacat
    27421 atatgccata aagatgcact tattttacgg agatttaaca aagtagtgta aagtatactc
    27481 taaatataaa ataaatcaaa tagagttaaa taaattgaga ggtgatataa atagtgaata
    27541 aaaaattgaa ctatagattt gaaatgaagc acaaaataac tgaagcagat gtgttagctt
    27601 taaaatcaag actctatcca ataatgaaga aagatgaaaa tgcatctaaa gatggaaaat
    27661 accttattag gagtttatat tttgatactc ctgaagataa agcacttttg gataaattaa
    27721 atggcattgc aataagagaa aagtttagga taagatttta taataatgac tgctcttata
    27781 taaggttaga gaaaaaaatc aaacattaca acatgacatc aaagctatca actaatttaa
    27841 ccaaaaaaga agtaataaat atactaaata atgatattga atttctaaaa gagtcgacaa
    27901 attgtttatt aagagaattt tatttgaaat taaaatgtga aagattagag gcaaaaagca
    27961 tagttgatta caatagagaa gcttttattt atccagttgg aaatgtaaga gttacaatcg
    28021 atagtgatat taaaacttct gtaaattcgg tagatttatt taataaagat ttgccaactg
    28081 tttcggtaat tgatgagaat atgactgtat tggaggttaa atatgatgaa tttataccag
    28141 attttataaa ggatttaatt caaattaata agactacctc tacagcagtt tcaaagtatg
    28201 cttcaagtag attatatatt taagaataaa ggctatgatt tatataaaga tatacataaa
    28261 taaggttaaa aaacaaataa gttaaaaata aataaaataa aaaataaata agttaaaaat
    28321 aggaaggatg attttaatta tgacatttaa tgatattttt aaatcaagtt ttatagaaaa
    28381 cgtatcaggt ttttcatttg tggacagtgc tttagcacta ggttcagctt ttttagtagg
    28441 tttgtttata tatatggtct ataaaaagac ttatatggga attatgtatt ctcgaccatt
    28501 caatgtgtcg cttgtagcac ttacaatgct tacaactttt gtaatattgg cggttacttc
    28561 aaatgtagtt ttatccttag gtatggttgg tgctttatct atagtaagat ttagaacagc
    28621 aattaaagac ccaatggatt tagtatttct attttggtca ttaggttcag gtatagtttt
    28681 aggagcaggt ttgattccct tagctgtcat gggttcaata attatgggat tgattctaat
    28741 attcttttca aataaaacaa tatctgaaac tccatatata ttgatggtaa attgtaataa
    28801 tgaagattca gaagatatag caactgataa aattaaaaaa gtatttacta aatatcaaat
    28861 aaaatcaaaa agtgttacac cagaaaaagg aatagaatta gtgtttgaag taagaatgaa
    28921 agatggagaa acaagtctta taaatgactt gagtcaagta gatggagtta ctaatgcagt
    28981 tcttgtaagt tataatggtg actatgtagc atagagagga gtaatctttt atgaaagata
    29041 aaaaatttac ccttcttatc tcgattatga ttatattttt atgtgctgta gttggagttt
    29101 atagtacatc tagcaacaaa agtgctgatt tatatagtga tgtatatatt gaaaaatatt
    29161 ttaacagaga caaggttatg gaagttaata tagagataga tgaaagtgac ttgaaggata
    29221 tgaatgaaaa tgctataaaa gaagaattta aggttgcaaa agtaactgta gatggagata
    29281 catatggaaa cgtaggtata agaactaaag gaaattcaag tcttatatct gtagcaaata
    29341 gtgatagtga tagatacagc tataagatta attttgataa gtataatact agtcaaagta
    29401 tggaagggct tactcaatta aatcttaata actgttactc tgacccatct tatatgagag
    29461 agtttttaac atatagtatt tgcgaggaaa tgggattagc gactccagaa tttgcatatg
    29521 ctaaagtctc tataaatggc gaatatcatg gtttgtattt ggcagtagaa ggattaaaag
    29581 agtcttatct tgaaaataat tttggtaatg taactggaga cttatataag tcagatgaag
    29641 gaagctcgtt gcaatataaa ggagatgacc cagaaagtta ctcaaactta atcgttgaaa
    29701 gtgataaaaa gacagctgat tggtctaaaa tcacaaaact attaaaatct ttggatacag
    29761 gtgaagatat tgaaaaatat cttgatgtag attctgtcct taaaaatata gcaataaata
    29821 cagctttatt aaaccttgat agctatcaag ggagttttgc ccataactat tatttatatg
    29881 agcaagatgg agtattttct atgttaccat gggattttaa tatgtcattt ggtggattta
    29941 gtggttttgg tggaggtagt caatctatag caattgatga acctacgaca ggtaatttag
    30001 aagacagacc tctcatatcc tcgttattaa aaaatgagac atacaaaaca aaataccata
    30061 aatatctgga agagatagta acaaaatacc tagattcaga ctatttagag aatatgacaa
    30121 caaaattaca tgacatgata gcatcatatg taaaagaaga cccaacagca ttttatactt
    30181 atgaagaatt tgaaaaaaat ataacatctt caattgaaga ttctagtgat aataagggat
    30241 ttggtaataa agggtttgac aacaataact ctaataacag tgattctaat aataattcta
    30301 atagtgaaaa taagcgctct ggaaatcaaa gtgatgaaaa agaagttaat gctgaattaa
    30361 catcaagcgt agtcaaagct aatacagata atgaaactaa aaataaaact acaaatgata
    30421 gtgaaagtaa gaataataca gataaagata aaagtggaaa tgataataat caaaagctag
    30481 aaggtcctat gggtaaagga ggtaagtcaa taccaggggt tttggaagtt gcagaagata
    30541 tgagtaaaac tataaaatct caattaagtg gagaaacttc ttcgacaaag caaaactttg
    30601 gtgatgaaag ttcaagtgga attaaaggta gtgaaaagtt tgatgaggat atgagtggta
    30661 tgccagaacc acctgaggga atggatggta aaatgccacc aggaatgggt aatatggata
    30721 agggagatat gaatggtaaa aatggcaata tgaatatgga tagaaatcaa gataatccaa
    30781 gagaagctgg aggttttggc aatagaggag gaggctctgt gagtaaaaca acaacatact
    30841 tcaaattaat tttaggtgga gcttcaatga taataatgtc gattatgtta gttggtgtat
    30901 caagggtaaa gagaagaaga tttataaagt caaaataaga ttaaaattga atataaataa
    30961 ttttaatact gttaagtcta aatatttact tagcagtatt tttttagaaa ataatgtatt
    31021 tggttaataa tataaggtaa taaattgata aaaattaaat acagcatatt aataatacat
    31081 aataaagtaa taaaaaaact gtttaagtat aataacttat atttagacag tttttttcat
    31141 ttataaataa tataaatgaa attgaaaaca tttgaaggat agaaattggt tggataaatg
    31201 tataaattac ttcaccaaaa aataatgaca aaaattgtaa ctaagttgta ataaaatggt
    31261 agttatttag cataaaataa tgtatcatag aagtatatta taaaattaat aaaataagat
    31321 ttttgtaaga aaactgctgg cttttgatat ttagagtgag tagttaaatt atgtttagga
    31381 ggggtagaat ttgttgcaaa aagtattatg gaaattttta aagctagtag tcggtttatt
    31441 tatatgttca gttggtatag tattgacgat aaattgtaac cttggattat ctccctggga
    31501 tgtatttcat caaggacttt caaatcatat aggaataact ataggaactg cttctataat
    31561 tgtaggctct atagtagtta ttgctgatgt cgttcttgga gaaaatgtag gatggggaac
    31621 tgtttttaac atgctactaa ttggattttt tatggattta cttttatata gtaatttaat
    31681 tccagaggct gatagtttat ttgtaggaat aattatgttg atattaggat tggttctttt
    31741 gtctgttgga atggtatttt atatgggaag tggtttagga agtggaccta gagatggttt
    31801 gatggttgca attcaaaaga aaacaggaaa atcacttaaa ttaataagag gtactataga
    31861 agttggagca ttaatagtag gatttttatt aggtggaaaa gttggtatag gaactataat
    31921 aagtgcattt ggattggggt atttcacaca aatggtattt ggcttattta aattagattg
    31981 tagtaagatt aaacatagat ttatagtaga tgatataaaa tttatcaaag tgtatatgag
    32041 tggtgagaaa aaagctgctg ttcaaaatat agttaagtaa tttaagaata aattcaacga
    32101 aatgttaagt attttaaatt aacattttgt ttagatagat aaattgaata ttaaaagaat
    32161 attaaaatat gaggattgct agaacactat aaaatataga tttctagcaa ttttttattt
    32221 gttcaatatt tttttagtac tagaagtctt attctctatt taatgaatga attaatttat
    32281 aattagagat actaaacttt atagatatta atataaacac ctttaaactg tgtattttcc
    32341 aaagccttta aaatgcttgt atttattcta aataaaaaaa taaaaaaatg tcaaaaaaac
    32401 tcttgtatta tatccaaatt ttatatataa ttacctatgt tgtttagaaa ttttaaactc
    32461 aatgtttagt aaacaaaatg tttagtaaaa taaaacagaa actaggaggt gcaacatgga
    32521 tataggtgaa aagataaaaa gattaagaac agaaaaacaa ctgacccagg aagagttagc
    32581 taatagatgt gaattgtcaa agggatttat ttctcaatta gaaaataact taacatcacc
    32641 atccatagct acccttatag atatacttga aatactaggt acaaatttaa gggaattttt
    32701 taatgaaata gatgatgaaa gaatcagttt tacaaaagaa gatatgtttg aaactgaaga
    32761 tgaagattta aaatataaat taaagtggtt aattccaaat tcacaaaaaa atgaaatgga
    32821 gccaataata ataacattgt atccaggagg acagtataaa gaagaaaagc cacatgaagg
    32881 tgaagaattt ggatatgtat tagcaggttc aatatatgtc catataggcg aaaagaaaaa
    32941 taaagtaaaa aaaggagaga gtttttactt tagaccgaaa gcaaatcact atatatcaaa
    33001 cgagggcaaa actacagcaa aagtgatttg ggtaagtacg ccaccatcat tttagaatag
    33061 aggtgtttaa taattggtag aaaatataat agaattaagg gatatatcta aacattatga
    33121 agaacttact gttttagata atttcaattt agatataaag aaaaatgagt ttctaacatt
    33181 acttggacca agtggatgtg gaaaaactac aacattaaaa ataatagcag gatttgagta
    33241 tgctgatgat ggtaaagttt tatttgaagg taaggagata aataatttgc caccatatga
    33301 aagacaagta aacacagtat ttcaaaaata tgctttattt ccacacatgg atgtttatga
    33361 aaatgtagct tttggattaa aaattaaaaa gactccaaaa gatgtaatag atgctaaagt
    33421 aaaagaggtt ttgaaacttg ttgcactaga aggttttgaa agacgacaag ttgaatcatt
    33481 gagtggagga caacaacaaa gaattgcaat agcaagagct ctagttaatg aaccaaaggt
    33541 attattacta gatgaaccac ttggagcact tgatttaaag ttaagacaag agatgcaaat
    33601 agaattaaag agaatccaaa aaaaattagg aataacattt gtttttgtaa ctcatgacca
    33661 agaagaggct cttactatgt cagatactat tgttgtaatg tataagggca aaattcaaca
    33721 aatgggaaca ccacaagata tatacaatga acctaaaaat tcatttgtag ctaaatttat
    33781 aggtgaaagt aacatatttg atggaattat gatagaagat tataaagtta atttctgtaa
    33841 tagagatttt gagtgtgttg ataaaggatt cgaaaaaaac gaaaatatag aagtagtaat
    33901 aagaccagaa gatataaaaa tggtaaagcc agaagaagga atgttaaagg ggaaagttac
    33961 atctacagtg tttaaaggag tgcattacga gatagaattg aatgaaaatg gaagattgtg
    34021 gatacttcat aatactaaaa atgctgaggt tgggactgaa ctaggcatgg atatatatcc
    34081 agaagatatc catataatga gaaaagagaa taactaagat gaaaagaaaa tcttttttag
    34141 catatccata tgtagtttgg agtgcgatat ttgtaataat tcctttaata ttagtagtat
    34201 tttttagttt tacaaaagaa tcaggtggag gttatgcctt tacacttgag aattataaag
    34261 aagtaattga ccctatatat atgaaagttt ttgggcgttc tattctttta gcaggaggag
    34321 ctacattaat atgccttata gttggttatc cagtggcata tataatttca aaggctcgtg
    34381 taagtagaag aggttcatta atattattgt ttattcttcc tatgtggatg aactttcttt
    34441 taagaacata tgcatgggtt gctatattag gaaaaaatgg acttttaaat acatttttag
    34501 gttggtttgg aatacaacca ttagcaattt tgtatactaa ttttgctata cttttaggta
    34561 tggtgtataa ctttttacca tttatggttc ttccaatata tacagcacta tcaaagatgg
    34621 ataatgattt gataaacgct gctcatgact tgggtgcaaa taatatgaca gtttttagaa
    34681 aaattatatt tcctttgagt ttgccaggtg taatgtctgg aataactatg gtatttatgc
    34741 cagcagtcac tacttttgca atatcaagac tgttaggtgg aggtaaaata atgctggttg
    34801 gagatttgat tgaacaacag tttacagttg ttggagattg gaactttggt tcagctatat
    34861 cgatatttat gatgatagta atattaatat ctatgtctat aatgtcaaaa tttggagatg
    34921 aatctgacaa agaaggcggt gggttactat tttaaaatta aagaaaataa cttctaatat
    34981 atatttagca ttagtattct tatttttgta tgcacccata tttgctttgg tactattttc
    35041 tttcaatgat tcaaaatcaa tggcaagatg gaatggattt acatggaagt ggtatggtca
    35101 attacttcaa aatgagagta taatgagtgc tttatattat actattgtaa tagctatatt
    35161 agcgtctgta atatctacaa tagtaggaac tataagtgct ataggaatac ataagatgag
    35221 aggtaagagt aagaaattaa tactaaatgt aaactatctt cctattttaa atacagagat
    35281 agttacagca gtagctctta tgagtctgtt tgtatttgta aaaatggaat ttggatttac
    35341 aacaatgcta ttggcacata taatgttttg tttgccatac gttatacttt cagttttgcc
    35401 aaaaatgaag caattacctg ataatataga agatgcagct atggacttgg gagcaacacc
    35461 tatatacgct cttagaaaag taattttacc acaaataaaa ccaggtatag tttctggatt
    35521 tttaattgca tttactatgt caatagatga ctttataata agtttcttta atgctggaaa
    35581 tggtgtaagc aatctttcta tagaaatcta tggaatggct agaagaggta taaaacctga
    35641 aataaatgca ttatcaacaa taatgtttgc agtggttcta ggtttacttt tactagctaa
    35701 taaaaaagaa tctatagtaa gggggattaa ataatgatta agtttaaaaa agcaatatcc
    35761 cttatagctg taggtatgat gacagttact ttatttacag gatgtaataa agcaactgat
    35821 tctacaaaag ttttaaatgt atataatgtt ggagattata tagatgagtc tcttatagat
    35881 aagtttgaaa aagaaacagg aatagatgtt caatattcaa cttatgatac taatgaaatg
    35941 atgtatcaaa aagtaaagag tggtagtaca cactatgatt tagtatttcc ttcagactat
    36001 atggtagaga aaatgaaaaa tgaaggtctt ttggaaaaat tagattttaa gaatatacct
    36061 aatatgaaat atttagataa gagtttttta aatcctgtat acgacaaaac taatgaatat
    36121 agtgttgcat atatgtgggg aactcttgga atactgtaca ataagaaaga agttaaagac
    36181 cctatggata gctggaatat actttggaat ccaaagtata agggaaatat aatgatgttt
    36241 gactctgtta gagatactat agggataact cttaaaaaat taggatatag catgaatagt
    36301 gtaaatccaa aagaaataaa tgaagctaaa aatcttttaa tgaaacaaaa ggatttagta
    36361 ttggcttatg taaatgatga aggcaaggat agattgcttg gtggagaagt ggcaatgggt
    36421 atgctgtatt ctggagatgc agttacacta atggagcaaa atcctgacct tgattatgct
    36481 atacctaaag agggaactaa taaatgggta gatgctatgt gtgtacctac aacagcacaa
    36541 aataagaaag aagctgagct gtttataaac tttttattag acccagagaa tgcaaaagta
    36601 aatgctgagt acattgggta ttcaacacct aatacaggag cactaaaatt attagaccca
    36661 gaaataactc agaatcctgt tgcatatcca tctaaagaag tacttgataa atgtgaaact
    36721 tttgaagata ttggtgaaaa tataaaatta tatgacaagg cttggataga gttaaaatca
    36781 aaatagggtc ttgttgtttt aagtaaattt acttaataaa tacttaataa aactgttctt
    36841 ttttagaaaa tttattttct aattattgaa cagttttatt ttttgtttaa gttatattca
    36901 tatgcaattt aaatagttta ttaataaatg aaaacttatt tgtataatga ctttaataat
    36961 aattagaaaa aatgggcaac ttaatagaat aattggaggt gtaaatttat aaaaaatgaa
    37021 taggataaat aaaaaaatag atttattaat attggctttg ctcgttttta tatttttaat
    37081 tgttggaata gtaatactat cgattaggac agaaaataaa ttgaatgtgt tcataatgtt
    37141 agcaataatt ttttttataa taatgttaac ttatttatca aattcagtag tggggttgat
    37201 aacaagttca ataattatat ttatgtatac atcctatatt ttatataaca atattactca
    37261 caatatggat gttgaattta tatcatatat gtggataata gcaacaccag tatcttcaat
    37321 tataatgggt aatctgaaca aaagcataaa tgaattgcaa aatacaaata aaaaactatc
    37381 tgaacagtat aaggaattag tgactattga tagtgaaact ggacttagaa atttaaagat
    37441 tttttataat gatgtaaata tggagataag taaatctatt agacataata ctgatttttc
    37501 tcttatgata gtaaaattac catactacgg aaacctacag actatatttg gtgaaaacaa
    37561 aactaataaa atagtaaaat atattggttc aaatattata gaatgtacaa gaaatgaaga
    37621 tataatttat agtttacaaa aagatatgat agggatacta atgccaaata catctttgga
    37681 aggttcaaaa gttgttaaag acagaataaa gaaaaggata aaagaattaa atttagattt
    37741 aaacaatagg ggaaaatatg taaatataga tgtcaaaatt gcatttttac aatataagag
    37801 tagttttgga gatagtataa attttaagaa tatagttgaa gaggaacttc aatatgatgt
    37861 ttaaaatatt taataaaagt ctattaaaat tagtagttgt attatcaata gtactgacaa
    37921 tatcaaattt tagcttatct tcatatgcat cagaaattac ttccagcaca gataaggtat
    37981 taatcatata tgattctaag aaagaaacag cttataatag agatatttta aatattatga
    38041 ggactctatt gggaagattt agttcagata tagagctatt aaaattgagt aactatgatg
    38101 gtgagataaa taaaaattat tacagtcata tatttatttt aggaatcaat gaaaactcat
    38161 ataataatga taaaaacact aaaaacttga ttagttcctt aaattcatat aaaggaacta
    38221 tatgttggtt aggatatggt atagaaaatc ttttggaaca taaaaaatac aatttagact
    38281 atgtaggaaa aacaaacaat atagttagtg taaattatag aggtaaatca tataacttgg
    38341 atgaacatta tgtttttaac attgtagaat caaaagatac aagtaataaa gtaataggaa
    38401 gtattaatga taccttaaat aagtatccat atataataaa tgataaaaat cttttttatg
    38461 tatcaaaatt agatttagat ggagttttat tttatatatt ttgcgattca cttaatgata
    38521 tttttaatat taagacgttt gataaaggac gtatatttgt aagaatagaa gatgtacatg
    38581 cttttagaga accaaaaaat cttgtagaga tagcggatta tttaagtagt aagaatatac
    38641 catttacgat tgcattaata ccagcatatg taaatcctaa aaatcataaa gtaataactt
    38701 tatcagaaag ccctgaaatt gtcaaagcaa taaaatatat gcaagataaa ggtggaactg
    38761 tgatattgca tggatatact catcaataca agaaagaaga agtttctgga gaagggtatg
    38821 aattttggga tggtaaaaaa gatgaaccct taaaagaaaa tatgaagata tttgtcaaag
    38881 atagagtttt gaatggtctt agagtatgta tagagaatgg aatttatcct cttgcatttg
    38941 aagcaccaca ttatgcaatg gaatcagagg gatataaaga attaaaaaaa tatttttcta
    39001 cttatatggg gcaacatcaa aataatgata aaaaatttag cacaaataca tatccttata
    39061 ttattaggga tacagaagag tttaatatat ttatacccga aaatttagga tatatagacc
    39121 cagaagataa gtttactttt caaaatataa aagaaaattt agataaatta tccattgtaa
    39181 gaggttttag tggagggttc ttctttcatt catatttaaa catagagtat ctaaaaaaca
    39241 caatagaata tttagaaaaa cagaatatag aatttatgaa tttaagagat tttaataatt
    39301 gggtaaaagt tgatgaaata caaataagaa ataatggaga tgaaattata gtcaactatg
    39361 ataaggactt agatgaacta actaaaagtg atactagatt taaatccata tccaatatta
    39421 gtaaagtttt aatattcata gtatctataa gtgttttaat atttgtgatt atatttatat
    39481 attttaagag aatagataaa aagaaatttt taaaataaag gattttatat tagaatcaat
    39541 attttaaaat attttaggag aaatttatga gagatttaaa tgtatcagag tatttgttcg
    39601 tatttagtct gtttagtata tggtctttat tgcttataaa tattatttta gctatgggtg
    39661 gatatatatt ttattttaaa aactttgata aagaaataaa agaaattgat gaatatccta
    39721 tgatatcaat acttgttcct gctcataatg aagctaaagt gataggtaga actgtggagt
    39781 ctttgctatt actcaattat cctaagagta agatggaact tattgttata aatgacaatt
    39841 cttctgataa tagtaaagaa attttagaaa atataaagga taggtacaac aattataatt
    39901 tcactataat aaatacagat agtttaacag gtggaaaagg aaagtctaat gcattaaata
    39961 ttggatatac gatttcaaaa ggagatttta tagctgttta tgatgcagat aacacaccag
    40021 ataaaaatgc acttagatat ctagtacaaa ctatagtaat gaatgatgaa ttaggtgctg
    40081 ttattgggaa atttaggact cgaaataaaa ataaaaacct attaaccaaa tttataaaca
    40141 tagaaacatt aagctttcaa tggatgtcac aagctggtag atggcaactt tttaatctat
    40201 gtacaatacc aggaactaac tttatattga ggagaagtat catagaagaa attggaggat
    40261 gggatagtaa agcaattgca gaagatacag aaataagttt taggatatat aaattgggat
    40321 acaagataaa gcttgtacca caatctataa catgggaaca agagccagaa actgttaagg
    40381 tgtggataaa gcaacgtact agatgggcaa aagggaatat atatgtatta atgaaatata
    40441 taaaaaatat atttaaacag ggaagaaata agattgtgtt tgatatagct tacttttttt
    40501 ctgtatattt tctattttta acatctgtaa ttatatccga tattttattt gttttaagta
    40561 tatctaaact agtagaaatt tctattccaa ttaacttttt tctaatatgg atactatctt
    40621 atcttttatt tattatagaa gtgagtataa gccttactat agaaaaaggt gaagcaacaa
    40681 ttgaaaatat attcatagtg gcaataatgt attttacata ctctcaacta tggctgtttg
    40741 tagctataaa aggaatgata gagtatctaa aagatataat ttttaaaaga gaggttaaat
    40801 ggtataaaac agaaagattt tgattcatgt acaggaggaa ttaacatgaa aaaatttatt
    40861 atatcaatta tatctttagt attgtttttt tcaaatatat cacttatata caaagtaaat
    40921 gctgatgaga ctaaagttaa aaattataag tttgaaagag atataactat tgatggtgtt
    40981 ataggaagta atagtacttt ttttgaagta aataaaaatt gggatattga agaagtttta
    41041 ttgcatctta attttagtaa gagccaaata ttaaatggag atgtttcaag tttaactgta
    41101 ttgataaata atgtaccaat aaaatctatt aaattaaatg ctaagacaaa ttataaaaat
    41161 acattagaag tattagttcc aaaagattat ataattcaag gatataatga aataaaaata
    41221 aaaacataca aaacaatatc tgataaaatt tgccaagatg attccaatac tgggaactgg
    41281 atggttattc acaaagaatc atatatatca attagatata agcagaaaaa ggtagaaaac
    41341 tcaataaatg aatatccgta tccatatgca gaaattgaaa ataatcataa attagataca
    41401 actatagtag taccagataa tatgactaga ggacagacta cagcagtgtt taatttggca
    41461 tcagcatttg gaaaaataac aaaaaatgat gttttaaagt tagatgttaa attatattca
    41521 gaaatgaaaa attggtcaga tgataatatt atatatattg gtaaacctga aaatacagca
    41581 gaagaaattt tggatatttt aagtataaag gaacaaaccc tattatcttc aaactgtata
    41641 atcaagcaag tagattcacc atacaataag aataagaaga tgatggtggt aattggtagt
    41701 aatgaagatg atttaataaa ggcatcaaat ttattaatag aaaatagact ttctaaccaa
    41761 gttttatcat catcagtact tgtaaacaaa gagactaata taaaaattaa tagggaacaa
    41821 aaattaaatt taggtcattt aacattaaaa gacttaggat attctgactt tttgttggaa
    41881 ggagcattta atcaacaagc tttgtttgat gtcaaaatac caacgggtaa ggtattagat
    41941 gatggttcaa agattatctt aaatttaaga tattctgaca atttagattt tgaaaaatct
    42001 ttagttacag tgtctataaa tgatgttatt gtgggaagta aaaaattgga taggtcacat
    42061 tctaataatg ataagttaga attaaaaata cctaaagata tagataataa aaactattat
    42121 caagttaaat tgacatttaa tttgagtata aaaaattcga attgtgttac tagagagagt
    42181 aataatcctt gggcatatgt atcaaataat tcttatttgg cgttatctac gaaagaaaat
    42241 gaaaccttat cttttgaaaa ttatccgtat ccatttgtta gagatgatga atttaatgat
    42301 ttaactgtga taatgccaga ttattcaggg tcacaagcta tgacctggat gtttagatta
    42361 ggtgttactt taggtgcgaa tataaattca cataatggaa atataaatgt aattagagga
    42421 aaagaattta gtgacaagta taaggatact aatattgtag tttttggagt gccacataat
    42481 aattctgtta taaagatgtt aaataataat ttaaatataa agttcgataa aaattactcc
    42541 aattttatat caaatgataa gataagcttt attgatgatt atggaaaaaa tatttctacc
    42601 attcaattaa taaaatcacc atataataat caaaaaaata tcatggtaat tagttcaatg
    42661 aatgaaaaaa acttatattt aggaatggat tatttgttga ataaaagtaa agttaatgat
    42721 ttaaaaggag atacattgat aattgatgaa tacggagagg cagaagattt agcttataat
    42781 ttaaaatcta agaaagaagt aaaagattca agttggaata tgagtataaa taagacaact
    42841 aaagtatttt taatgatttc ttttattact ataattgtag ttatgatatt atcaatgcta
    42901 tatataaaaa aatataaaag aagataatat gataaattta ttattttaaa agaggtatat
    42961 aatttgagga aatatatgaa taaatttaaa ttaaaaagaa gtattttaat ctcattaata
    43021 atcttaattt ttatatttat agtttacttt gtaagtattg agttaaaaga taggagtcta
    43081 gtaaataatc aatataaagg taagattaaa tcggccaatt tatctgtaga ttatgaaata
    43141 aatcaagtta tgaaggatat agataaattg ggattgaata cagtaaatgt acctataatt
    43201 ataaatgtag agtccattaa ttctgatatt atgtcaatag ataataatag taaagaaaag
    43261 gcaattaagt taataaaaaa attaaataaa aaaggtattt caacaatatt agaggcatat
    43321 ccatggattg aaaatggaaa attgtatgag actgactgga accctataaa taaaaaaaga
    43381 tttttttata cttggcaaaa tgccatatta aatgaactta taattgatgt agcaaatcca
    43441 ctggatgtaa atgttttaaa tattggttct aattttgtac atttggaaga atatcaacaa
    43501 aattggggtg aaataataga ttttgtacaa tccaaatttg acggtcttgt aacgtacaga
    43561 actaattggt ggtatacaaa aaaagatgat ttaagtagta agttgtttta tgaacaaaag
    43621 ctgaacaata atttttttga taagttagat tttatatcta tagcagcata ttttgagtta
    43681 agtaataaac ctgttaatac agtggatgaa ttaatttctg cattacactc atctactgta
    43741 aacaatagag gacaaaatat aaaacaagaa atatataacc tttataaagc tcatagaaaa
    43801 cctatatttt ttggagaatt aggtttttca aatagagaaa gtgcaagttc tcagccgtgg
    43861 aatcatactc cttcaaaagt tgtaaatggc gaagaacaag caaggtgttt tgaggcatat
    43921 aagaaagttt ttgaaaatga agactggata aatggttttt ctgtgttttg tgtaggtaaa
    43981 atagatgacg aaaaaaattt ttacccatca aaagagagta taaaagttat taagtcttgg
    44041 tatgaataat tttgaaagtg tagaatttat atagattaaa tagatgatta ggagagatat
    44101 aaatgaatga catcaaggtt atgactgtat ttggaactag acctgaagct atcaaagtag
    44161 cacctttaat aaaggaactt gaaaaaagag agaatataaa aagtattgtt tgcgttacag
    44221 ctcaacatag agaaatgctt gaccaagtta tagaaacctt taatataaat gtagactatg
    44281 atttggatat aatggaaaaa ggacaaagcc tgaatgatat aacatgtaag attttaaata
    44341 aacttccctt gattttaaac aaggaaaatc caaatataat attggtacat ggagatacaa
    44401 ccacaactct agctacaagt ttgactgcat tttataataa aactcttgtt ggtcatatag
    44461 aagctgggct tagaacctat gataaatatt ctccttttcc agaggagcta aatagacaac
    44521 ttacaggtat tattgctgat atgcactttg ctcctactaa tttggctaga aaaaacttga
    44581 tttctgaagg aaaacctaat aataatatat ttgtaactgg taatactgct attgatgctt
    44641 taaagatgac aataaaagaa aactataatc atcctataat tgatgagatt ggtaacgata
    44701 ggatgatttt gttaacctct cacagaagag aaaatttggg taaacctatg aaaaatatat
    44761 tcagagctat aaagcgaata gtagatgact ttgaagatgt acagatagta tatcccatac
    44821 atttaaatcc taaaatacga actatagctg atgagatatt tggaaaattt cctgaaaaaa
    44881 ttcatattat agagccttta gatgtagctg attttcataa ctttttaaat aaatcttata
    44941 tgataatgac tgatagtgga ggaatacagg aagaagctcc atcattaggt aagccagtcc
    45001 ttgtgttgcg tgataaaaca gaaagaacag aaggaattga agcaaagaca cttaaattag
    45061 taggtactaa tgaagataga atatataatt cagtgagcga tttattaata aataaagata
    45121 actatgttca gatgagtaaa gcatctaatc catatggaga tggaaatgca agcaaatata
    45181 tagtggatat aataattaaa aaatttaatt gcaaatattt aaattagata agggctaaaa
    45241 cattaactaa ttgatataag atttatgata atattaagga atacaatttt taagggggag
    45301 taatatggct agaaaattaa taaaaaattt gggtaaaagt aaaagtgtaa agagagtgaa
    45361 acttttattt aagaagattt ttattactgt attcatagta gcaagtatag ttgctatttt
    45421 taatataacg aaatattttg aggaattata caaagtaagg gatttaaaaa gtactaaaat
    45481 tgaatactat atggatgtgg ctgatgaagc aggagatgga aaggtccaat taagttggaa
    45541 ggccttactt gctatagaca tggtaataca tgatgaagat ttaagtaata taaaaaagaa
    45601 agacacattg gatatagggg aaaagtttat agtagaagat aaaaatgata aaggcgaaaa
    45661 ggtgtataag gtaaaaaagt ttaataaggt attaagcgaa ttgaaatttg actcttctca
    45721 aaaaagtaga gcaagaaaat acatgaaaga tttggaatac acataccttg gaaataaaca
    45781 attagatagt agtgatgaaa aaattaaatt tataaagaag ttagaagact cagctataag
    45841 agaatatatt gattatggaa tattgccctc tataacaatt ggacaagcta tattagaatc
    45901 tggttgggga aattctaaac ttacaaaaca gagtaataat ttatttggta taaaagcaga
    45961 taaagcatgg aaaggaaaaa gtgtagaaat ttcaacttca gagcattata atgaaaaaat
    46021 tgtagctagt tttaggtcgt ataattcatt acaagattct gtcaaagacc acagtttatt
    46081 tttaattaat aataaaagat atagaaaaca tgggttgttt gaggcaaaag attatattag
    46141 tcaagctcaa gcattagaaa atgcaggata tagtacagca gaagataaaa aaggaaatcg
    46201 tatatatgca gagctattaa tagatgttat taggagttat aatttgcaat tgatagataa
    46261 taaagttgag acaaaataat tgttaacttt atatgatgag ataacaacat aagattcttt
    46321 tctacaaaaa gaatagaaaa attgtaaaaa aaactaaaaa aatgtattga cttgttattt
    46381 aaaaggtgat attattatta ctgtactcga aagagaacaa aa
//
LOCUS       DAEORM030000029        45046 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.029, whole genome shotgun sequence.
ACCESSION   DAEORM030000029 DAEORM030000000
VERSION     DAEORM030000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 45046)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45046)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 45046)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45046
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.029"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            66..142
                     /locus_tag="KRH23_002110"
     tRNA            66..142
                     /locus_tag="KRH23_002110"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:100..102,aa:Arg,seq:acg)
     gene            155..230
                     /locus_tag="KRH23_002111"
     tRNA            155..230
                     /locus_tag="KRH23_002111"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:188..190,aa:Val,seq:tac)
     gene            306..719
                     /locus_tag="KRH23_002112"
     CDS             306..719
                     /locus_tag="KRH23_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5225390.1"
                     /translation="MYIVIGNEIVDSEELKIIIDKNSEFKVEKDLSKSTKREDVIAYQ
                     LSIDLNYLDSLINEQCNLASLSDEEKFDEYMTLSDELALDLEELMPKYTIINARAYKL
                     DEVDGIVKIILAVAYADLGHLKLSDVVKRLSRQVD"
     gene            1028..4459
                     /locus_tag="KRH23_002113"
     CDS             1028..4459
                     /locus_tag="KRH23_002113"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004736 - pyruvate carboxylase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0009374 - biotin binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006090 - pyruvate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase"
                     /protein_id="HHS5225391.1"
                     /translation="MLKKFNKILVANRGEIAIRIFRACSELGIKSVGIYSKEDKYGLF
                     RTKADESYLIGEGKGPIDAYLDMDGIIDLAKRKKVDAIHPGYGFLAENAEFARKCEEN
                     GITFIGPSSKVMNMMGDKINSKKIAKEVNVQTIPGVEKAIRSTEEAKEVANKIGYPVM
                     IKASNGGGGRGMRIVHREEDLELEYETACSESRKAFGEDIIFIEKYIADPKHIEVQIL
                     GDNYGNIVHLYERDCSVQRRHQKIIEYAPAFSLDDKVRKEICEDAVKLSKHVGYSNAG
                     TLEFLVDANGGHYFIEMNTRVQVEHTVTEMVTGIDIVQSQILIAQGYSLDSEEINIKS
                     QDDVEIRGYSIQCRITTEDPKNKFMPDTGKIQVYRTGSGFGIRLDGGNGFTGANISPH
                     YDSLLVKTISWDRTFQGAINKTIRSIKELRVRGVKTNVGFLVNVLNNPIFSNGKCSTK
                     FIDENPDLFEITESKDRGTKLLQFIGDVIVNDNACKEKPLFDALHDPRMDKDGSKSEG
                     SKILFDKLGKSAYIEKIKNDKKLLLTDTTMRDAHQSLLATRIRTYDLLKAAKPTEKYQ
                     KDLFSLEMWGGATYDVAYRFLKESPWRRLQKLREEIPSIMFQMLLRASNGVGYKNYPD
                     NVIEEFTKESARQGIDVFRIFDSLNWVENMKPSINTALETGKIVEATMCYTGDILDKT
                     KTKYNLEYYIKMAQELESLGADIIAIKDMSGLLKPYSAYTLVKELKKNVKAPIHLHTH
                     DTSGNGVATCLMASEAGVDIIDAALESMAGLTSQPSLNAIVEALKNTERDTGIDLFGY
                     DELGKYYKDLRKVYNKFESDLTNSCAEIYNFEIPGGQYTNLKPQADSLGLVNRFDEVK
                     EKYKEANEVVGDIIKVTPSSKVVGDLAIFMTKNKLDKDNIIEEGKNLSFPDSVVDYCK
                     GMIGQPEGGIPKDLQEVVLKGEEAITVRPGSLLPAEDFDEIAKYLNEKYDINANIRNV
                     ISYALYPKVYEDYIKHLQHYNDISKLESDVFFYGLNKNEECEVEIEEGKVLTIRLVEI
                     GEVKENGFRTIGFELNGMVREVEIKDKNFSGKINNVEKADMNDPLQIGASIPGKVIKI
                     MVKEEDEVKANQPLIVIEAMKMETIIVAKTDGVIKSIKVKEDDMVEDKQLLMIMK"
     gene            4701..6629
                     /locus_tag="KRH23_002114"
     CDS             4701..6629
                     /locus_tag="KRH23_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HHS5225392.1"
                     /translation="MKVYDSKMLRNVAVLGHSGCGKTNLIETIAYTANTNKIPKLTDK
                     VNMTYSMGLIPIEYNDYKFNLLDTPGYFDFSGDVVSSLRASDAAIIVIDATAPIQVGT
                     EKSLELTESIPKIMFINKIDNEKARYKDAIAMLREKYNNKIVPMISPIYKDKNFVKLH
                     NVFENIDDLEGEFKEQAMSVKEALMELIAETDDQILDKYFNGEELTTEEIQKGIIIGI
                     QRGDIIPVICGSTINNIGTKEILDTISSYLEPIFTEESKPFRGLVFKTMVDPFVGKMS
                     YIKITEGVLSKDKDVFNINKNVKEKIANIYTLRNSELVEIEKAKAGDIVVITKVNSLK
                     TGDTISADKDAEALEKIDFPKPQIYYAVTPKNKGDEEKVASVLNKLVEEDPTLHWYRN
                     TETKQALLGGQGELHIKTIKNKMKDKFGVDVELNDLKVPYRETIKGTADVQGKHKKQS
                     GGHGQYGDVKIRFERCESDFEFTEEIFGGSVPKQYIPAVEKGLKDSMQKGILAGYPVT
                     NIKATLYDGSYHDVDSSEMAFKMAASAAFKKGMEEAHPILLEPIMKLKITVPEEYMGD
                     VMGDINKRRGKIFGMEPDDKGKQIIFAEAPQAETFKYAIDLRAMTQGRGYFEMELERY
                     GEVPSQFAEKIIGLATAK"
     gene            7082..7546
                     /locus_tag="KRH23_002115"
     CDS             7082..7546
                     /locus_tag="KRH23_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HHS5225393.1"
                     /translation="MATMTDIIEKFIKDLMEEDNSIQIQRNELANLFSCAPSQINYVL
                     TTRFTIDRGYYIESKKGGGGYVQIEKIRKSKDGHIRELLNEKIGSQISYKKAKELLEG
                     LKESDLINERELKLILYAIDDKSLCMPIYELKEKVRSNILKNIIIGLFSIEE"
     gene            7553..8047
                     /locus_tag="KRH23_002116"
     CDS             7553..8047
                     /locus_tag="KRH23_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UvrB/UvrC motif-containing protein"
                     /protein_id="HHS5225394.1"
                     /translation="MLCQKCNKNKASVYYNKIVNGEKTEMYLCSECAKENTEMNFNLD
                     MPFSMMDIFSNLGFQPKKELEEKLVCPKCNTTYSEFKNNGRFGCSECYNAFSSQVNPM
                     LQNIHGHIEHTGKAPKKSFYKISVENEIKELKEDLDRAIKNEEYELAAQFRDKIKYLK
                     GSID"
     gene            8063..9088
                     /locus_tag="KRH23_002117"
     CDS             8063..9088
                     /locus_tag="KRH23_002117"
                     /EC_number="2.7.14.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0046314 - phosphocreatine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="protein arginine kinase"
                     /protein_id="HHS5225395.1"
                     /translation="MKENIVMKSRVRLARNLNNYPFPNKLDKECAMEIIEKVKNAFIN
                     SNLEQKEEFDFYKIEDLDQSKKMLMVEEHIISPDLAENDKSAVIVKKDKTISIMINEE
                     DHIRIQTICDDLNLEYAYSVANEIDDLLESSLEYAFNTKLGYLTSCPTNTGTGMRASV
                     MMHLPALSQLGYMDELYKISSQIGIAIRGIYGERTEALGNIYQISNQLTLGRTESNII
                     ENVSGLTKDAISKEIKAREILQKKLGIKLEDKIFRSIGTLENSRVMSSSEAMSHLSNI
                     KMGIEMNYIDKLDLRAIEQLMIGIQPAHQSIMYKSDDVENRDINRATYIRETLEKLRG
                     GMNCELQ"
     gene            9075..11522
                     /locus_tag="KRH23_002118"
     CDS             9075..11522
                     /locus_tag="KRH23_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HHS5225396.1"
                     /translation="MNFNRFTQRAKKAIDLAFESAKSLGHNIVGSEHILLGLLREEEG
                     IAAKVLSKVGFTEAYLEGKIVDMEGKGEEISEDIVLSPRSKQILELSGMFANKLKTNY
                     IGTEHILLAIIQEGEGIANKILNYAGVNDRTLAQLTIDMMGISDKNQYKAENSYTGNQ
                     NQAESKVLDKYGRNLTLYAKQNKIDPVIGREKEIQRVIQILSRRTKNNPVLIGDPGVG
                     KTAIAEGLATNIALGNVPETLKNKTLYSLEMGSLLAGAKYRGEFEERIKEVVDEVVKN
                     GNIILFIDEMHTIIGAGSTGEGSIDASNILKPALARGEIQVIGATTIDEYRKHVEKDS
                     ALERRFQPVMVDEPTKEDSIKILEGLRDKYEAHHKVKITDDAIKAAVELSTRYISDRY
                     LPDKAIDLIDEAASKVRLKENTPPSEIKKLELEIENIDKEKEEAVRCQDFEKAAKIRD
                     EQGLLKKQLEDVRERWNKSSKHSDLVDGEVIAEVVGLWTGIPVNKILEEEADRLLRLE
                     EILHNRVIGQEQAVKSISKAIRRSRAGLKDPNRPIGSFLFLGPTGVGKTELSKALAEV
                     QFGDENQIIRIDMSEYMEKHAVSRMIGSPPGYVGHDEGGQLTEKVRRNPYSVILFDEI
                     EKAHPDVFNILLQILDDGRLTDSKGRTVDFKNTIVIMTSNVGASTIGRQKTLGFSIAK
                     GDEEEKSQYEKMKENIMGELKQRFRPEFLNRIDDIIVFHSLNENHISKIVLLMAAKLQ
                     ERLKEMDIKLEMSDEAVKLISKSGFDLEYGARPLKRALQKELEDELSEAILKGNVKKG
                     SNVVAKVKDEKIVFETK"
     gene            11702..13075
                     /gene="radA"
                     /locus_tag="KRH23_002119"
     CDS             11702..13075
                     /gene="radA"
                     /locus_tag="KRH23_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HHS5225397.1"
                     /translation="MAKIKTKYVCQSCGYETAKWLGKCPECTKWNTFVEEIDQKSTKK
                     EVFIIDKSSSKPVSINSIESKEEERFTTDINELDRVLGGGIVKGSLVLVGGDPGIGKS
                     TLLIQVSSNVANLGKTVLYITGEESESQIKMRAKRLGINSENLYIFAENNLSIIESYL
                     ESVNPELIILDSIQTVFSPEISSAPGTVSQIKEGTSKFMKISKKMGISTFIVGHVTKE
                     GSLAGPKLLEHMVDTVLYFEGERYNTYRLVRAVKNRFGSTNELGVFEMRDLGLVELDN
                     PSKILISEKPKDVAGSVIISTVEGTRPMLLELQALVSPTSFGIPKRTSTGVDYNRVGM
                     LLAVLEKRVGLQIQNQDVYINIVGGIKINEPSIDLGIAISVASSFRNIPIDEDIAVTG
                     EVGLTGEVRAVSFIEKRIAECKKLGFKKIVVPRSNYDVVKETKGIEIWPVDNLRQAIN
                     IVLGRNQ"
     gene            13078..14148
                     /gene="disA"
                     /locus_tag="KRH23_002120"
     CDS             13078..14148
                     /gene="disA"
                     /locus_tag="KRH23_002120"
                     /EC_number="2.7.7.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA integrity scanning diadenylate cyclase DisA"
                     /protein_id="HHS5225398.1"
                     /translation="MENFLDNKNMLYALKMISPGTPLRLGLNNVLRAKTGGLIVIATN
                     EDVMKIVDGGFAINAEYSPSYLYELAKMDGAIVLSGDVKKILFANAQLIPDYFIETSE
                     TGTRHRTAERVAKQTGAIVIGISQRRNVITVYRGNEKYVVEDISKIFTKANQAIQTLE
                     KYKTVLDQAVTNLNALEFNDLVTIYDVALVMQKMEMVMRVTSIIEKYVIELGDEGTLV
                     SMQLEELMGTTRIDQKLIFKDYNKENTEIKELMKKVKNLNSEELIELVNMAKLLGYSG
                     FSESMDMPIKTRGYRILSKIHRLPTAIIENLVNYFENFQQILDASIEELDEVEGIGEI
                     RATYIKNGLIKMKQLVLLDRHI"
     gene            14237..15331
                     /locus_tag="KRH23_002121"
     CDS             14237..15331
                     /locus_tag="KRH23_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN/TRAM domain-containing protein"
                     /protein_id="HHS5225399.1"
                     /translation="MIRKVTRILFILLGFTIGITTYLTLMKDFEILTFGKETYGYIAA
                     VVAGIIIAILGYLIEPWVVNKVKEIAKIVDKELSKYPQTDILLGSMGLIVGFVIAYLL
                     SGLVNRIPIVGGILSLLLYLFLGYLGMKVALKSKNDLFNIGKLGRLANPIKDKDKDKE
                     NKKEVKAIPPKVLDTSVIIDGRIADICKTGFIEGKLIIPAFVLEELRHIADSSDDLKR
                     VRGRRGLDILNIIQKELNIEVEISERDFDDIAEVDSKLLKLAQVLNGKVVTNDYNLNK
                     VAQFQGVEVLNINELANAIKPVAIPGEDMVVQVVKEGKEAQQGVAYLDDGTMIVVDGG
                     RKYMNETIKVLVTSVLQTPAGRMIFAKPKN"
     gene            15460..17637
                     /locus_tag="KRH23_002122"
     CDS             15460..17637
                     /locus_tag="KRH23_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5225400.1"
                     /translation="MRKKIISFLATFIIILTSASQYSFADDISTRGKVIFIDMNRTSM
                     SNMLRIKSLREELDNRGYIGLMNIRGDKGSDDRRSYASMGAGGRANVANEEDINFESS
                     SKDRNIVFESATGKSAKGINNLTINKSINENLNFGEYGSVLGSLGQSLSDNGLKASVL
                     GNSDIIENGQLIKNRNLCLTAMDEYGRIPNGNVDTINKKDLSMPYGISTDYDKLIVET
                     KEAYKNNDVIFVELGDTYRLDLYKPNLNEKTYESMKDNIEKNIDIYLKNIFSMVEEND
                     TIYIASAFPSDLDYKNKRRLSPIIKLNGEGKGILSSSTTRREGIVTNLDVGVEILDNF
                     NIKNQNMVGRKYELINRDDNKEFLMDEYQKIVSISSIRSTILNGFVSIVFLSWIVAMI
                     AILFRKHISKNYKETTFFILKELLKIGIVMPLSFMITPIMNFKTPLAISLGIIIITLT
                     IYLISKVLIKNDLKNMLFFTGLTIVIMVIDAGFGSYLMKSNVMSYDCIIGARYYGVGN
                     EYQGVAIGSAIFTFAILLTYKNIPKWSIIVFSLVILITSASPIMGANVGSAISECVAF
                     LLFILLIYNVKIDFKKIVLLGIAVLFVLGVFVAIDMILGSNSHLGMFVKEIYFNGPGE
                     IIQTFSRKIEMNLKLAQTSAWVNILLTGIGVILVLMINQIRYFKQLMDEYPIVFKGFI
                     ASIAGCLVTLLVNDSGIVSSATAFIYVIVPMITLSINLTALKE"
     gene            complement(17816..17980)
                     /locus_tag="KRH23_002123"
     CDS             complement(17816..17980)
                     /locus_tag="KRH23_002123"
                     /inference="COORDINATES: protein motif:HMM:NF024242.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5225401.1"
                     /translation="MRISHIYKDLINTNDTLCSILEAHGFTNTKLFYRIFKEKFKCTP
                     KHIRKNLPKI"
     gene            18087..18269
                     /locus_tag="KRH23_002124"
     CDS             18087..18269
                     /locus_tag="KRH23_002124"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5225402.1"
                     /translation="MYLLKKDKGTFNSSGIFISTSIFEFRVENGSGSAILQIIKISFY
                     EFDKKYNTILNELNVK"
     gene            18530..19483
                     /locus_tag="KRH23_002125"
     CDS             18530..19483
                     /locus_tag="KRH23_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HHS5225403.1"
                     /translation="MKKIGDLRLMMKCCSLYYEDNLNQQEIANQLGISRPTISRILKE
                     AFEQGIVKIQIVDVLKNDYQKIERSLERKYKLKEVIVVDDKQDALTQKQELARAVSEY
                     LTRVVKENDIIGVSIGTTLKEIPRYVEKSNCKNVTFIPLLGGIGDNEIDIHANQIAVS
                     LARAFGGDFKLLHAPAVMSDLSTKEKLCKDEKIKEVLDLIDKTTIAIVGIGNPMSLNS
                     TIMASGYMNEADIEDLKKYNSIGAICLQAFDKEGKTSILEFNQRVLGVKLEDLKKIKR
                     TIGVASGDEKIEAIKASLKAKFINSLAINHSLALKLLEDCD"
     gene            19521..20483
                     /locus_tag="KRH23_002126"
     CDS             19521..20483
                     /locus_tag="KRH23_002126"
                     /EC_number="1.2.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016624 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, disulfide as
                     acceptor [Evidence IEA];
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HHS5225404.1"
                     /translation="MSISKETLLEMYKRMNQARKFEEKVSWFFARGMVHGTTHLSVGQ
                     EASSVAAVMALEKGDLVSLTHRGHSQFIGMGIDLNKMMAELMGKETGFCKGKGGSMHI
                     ADIESGNLGANGVVGGGLTIAPGAALTQQYKKTGKIVLCSFGDGASNEGTFHEGINLS
                     SIWKLPIIFYCENNLYGMSTSIKRHMNIESIATRAASYGIEGISIDGYNPIEVYETVQ
                     KAAEKCRRGEGPVLIESRTYRWLGHSKSDANVYRTKEEIESWKAKDPIEFLKNYLIEN
                     NLSNEDELDKIQEFAKQSIEDAVEFAQNSPNPKIESLLEDVYAD"
     gene            20508..21494
                     /locus_tag="KRH23_002127"
     CDS             20508..21494
                     /locus_tag="KRH23_002127"
                     /EC_number="1.2.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HHS5225405.1"
                     /translation="MSTRELTYAQAIKEAMSEEMRRDENVIFMGEDIGIYGGAFGVSV
                     GMIDEFGPERVRDTPISEAAIAGAAAGAAATGLRPIMEVMFMDFVTISMDAIVNQAAK
                     MRYMFGGKAQVPMVVRCPGGSGTGSAEQHSQSLEAWFCHVPGVKVVAPSTPADAKGLL
                     KAAIRDNNPVIFVENKLLYRKKGFVPEDDYVIEIGKADIKREGTDVTVITYGRMLQSV
                     EEAAETLSKENINVEIIDLRTLYPLDKETIVKSVCKTGRVLICHEAAKTGGLGGEISA
                     LITESESFDYLDAPVKRICGKDVPIPYNPELEKAVVPRVDEIEEAIKSLIVR"
     gene            21507..22553
                     /locus_tag="KRH23_002128"
     CDS             21507..22553
                     /locus_tag="KRH23_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxo acid dehydrogenase subunit E2"
                     /protein_id="HHS5225406.1"
                     /translation="MVANKIKATPAARSQARKDNIKLDRLIGSGENGRIHLVDVLNYL
                     KDNKANTTPLARRIAEDLNIDLETIVGTGYNGKIRKCDVEKLTAKETIVSTNTSKSSE
                     KKELKIENENSSMFNTVEGIFEKPNPMRATVAKRMSESYFSAPVFTFNIEVDATELKV
                     LRAKLIDTVKESTGVKLTMTDLIVMAVSKILPNHQALNSAWTDEGIFRYKDVNIAIAV
                     GLDEGLYVPVVKNANKKSLKEIAKESKELAEKVKTGKLMPADQEGNTFTISNVGMYGI
                     TTFTPIINMPSSAILGVGATQDKFVPVNGEAKIKPIMNLSLTSDHRVIDGTVAAKFLK
                     DLKELLENPLSMLV"
     gene            22720..24450
                     /gene="lpdA"
                     /locus_tag="KRH23_002129"
     CDS             22720..24450
                     /gene="lpdA"
                     /locus_tag="KRH23_002129"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004148 - dihydrolipoyl dehydrogenase
                     (NADH) activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HHS5225407.1"
                     /translation="MSVEVIMPKAGVAMEEGTIVSWLKQEGEEVKIGEPILEITTDKV
                     NMEIESEGEGTLAVIIHKEEGEVLPVFTVIGVIAEKGENQEEVKAKYLSGNVSKEDTV
                     KENQNIEVKEEKINKKECNHDYDVVVIGGGPGGYLSALKAALLGGRVALVEENILGGT
                     CLNRGCIPTKTYIKTAEILEEIDQLSKRGVKVTVDKEQDIKKAIKYKNRVVKKLTAGV
                     GGLLKSRDVDVFNLKASVKEEHKVILSDGKVLDTENIIIATGSKVRILPIKGIESNLI
                     ITSTEALDLETVPEELVIIGGGVIGCEFAEIFNSRGSKVTIVEMEDRVIPRMDKELSE
                     SLKYSLSKKGINVLTKKKVSEFKEEGNNILVCIEGEEPIKADLCLYAIGREANLSGIE
                     DLDIKIDKGSIVVNSKMETSIPSIYAVGDVTGGVMLAHAAFKMGEVAASNALGVNKEV
                     DLGALPSCVYTIPEVASVGITEEDARKKYNVKVGKFNFAGNGRALASGQEQGYVKVVA
                     DAKYGEILGIHMFGCGVAELINHAASFKALEIPTDEASELIFGHPCTSEALMEALADV
                     NGECLHLPKK"
     gene            24868..27816
                     /locus_tag="KRH23_002130"
     CDS             24868..27816
                     /locus_tag="KRH23_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HHS5225408.1"
                     /translation="MRQRIKNLIENEDKKNPLTDEAISSRLNIRREDVTFLRNELKIE
                     DSRQRRKVVLIKAIKDILKEEKTINKNDITRRLNSIGFTVSRFTVIQYLKEIQDSGDL
                     KLDKESDDKKEKIINNRENKDIAFDKLIGSSGSLSTIIKLAKAAILYPPHGLHTIIMG
                     PTGVGKSELAECMYKFAVESSRFPKNAPFIVFNAADYSENPQLLLSQLFGHVKGAFTG
                     ADENKEGLVSKADGGILFIDEIHRLPHEGQEILFQLIDKGMVRKLGETRLTHKIDVMI
                     ISATSEPIDSHLLNTFKRRIPVTIEIPELVARPLNERFDIINNFFLIEAQRMGANIHI
                     KSDVLKALMLYDCIGNVGQLRSDIQVACARGLLNQLTNKLKEVNISISDVPGYVKQGL
                     IKIRNCRGKIENYVDGDLIIDSNLQGEIEKKNEDIYTFPDEIYKLTERRHIDLLEQGL
                     DFDVINRIIGGELESCIQKYIKQVKKVSISNNLPDISPIVGKYIVELTYEVIKIASQY
                     LSSLEPNLHLCLAVHLKAAFERLKEGKVISNAHLKEIIGNYPVEYSVAEKVAQYLKER
                     YNINLPKEEIGIIAIYFKMSSRRDMSEQKKIGVLLMAHGRVASSVCEVTNKLLGINHA
                     RYLDMPFEKKPEEMIEEATTIIKDIDEGRGVIILVDMGSLSYFGDIISGKTGINIRTI
                     SRFDTLLSIEVIRRAVLPDLTIDEIVDEVKGIEPQVKEKVSKCNNTKVDFRKPIILTL
                     CITGLGGACKIKKILEENIKSITEKVDIEPIGMIEYPSLDLEIKQISNDKNVIAIVGT
                     IDPQIANIPFFSLVDINDKAKLNQINNLIDTNQIGETNKKYELSDLIHKEDIFVDLQV
                     KSKEEVLKYMSKKLREKGYVTKNFYKKVVERDNLFPTELSDEIAIPHTDGIDVIRPAI
                     SIAILKKPIVWSKSKVKIILLLAVDQKCFNPLSTLLSFIETDEFKKIKNIKDRDFIRE
                     MILDGVNENN"
     gene            27794..28258
                     /locus_tag="KRH23_002131"
     CDS             27794..28258
                     /locus_tag="KRH23_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HHS5225409.1"
                     /translation="MESMKIISSNLIFKNIEVSNNEDALKFLGQRLFDEQYVKESYIQ
                     AVVAREKKYATGLPTEIYGVAIPHTDIVHVNEPGIAIGILNKPVKFIMMGTDDTEIDV
                     KVVFMLAVKEPQEQLQLLEKLMTIFQDKNILNNIVDLSEESVSDLLNSKLKN"
     gene            28371..28673
                     /locus_tag="KRH23_002132"
     CDS             28371..28673
                     /locus_tag="KRH23_002132"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HHS5225410.1"
                     /translation="MGVTNVAKKILVACGTGVCTSTIAINKLKKALQDIGKLDMVNIT
                     QCKVVEVASKAPDYDLIICTTQVSSSIKTPVINGLPFLTGVGMDKLINDVLEELEL"
     gene            28750..30099
                     /locus_tag="KRH23_002133"
     CDS             28750..30099
                     /locus_tag="KRH23_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HHS5225411.1"
                     /translation="MEILNFIVGLGAQVMMPIIICIFGLILGTKLGKSLRAGLTVGVG
                     FIGLNTIIALLTDNLGPATQQMVKNLGLSLSIIDVGWPAASAIAFASTVGALIIPIGL
                     VVNIVMLITNTTQTVDVDIWDYWHFAFTGALVAGATQSVMWGVFAAVANMVIVLVMAD
                     LTAPGIEEYLGMPGISLPHGFTQAFVPIAIVVNKLLDLIPGINKIEINADTLQKKFGL
                     FGEPLIMGSVIGVIIGIAAKYDIKGILQLGVTMGAVLILIPKMAALLMEGLLPVSEAA
                     QEFIEKRFKNRGKIYIGLDSAVGIGHPVTLSVALVLVPLTILIAAILPGNKVLPFADL
                     AVIPFALVLIVPITKGNVFRTLIIGIIIITSGLLIATNLAPLFTQMALNASFKMPEGA
                     TMISSICDGANPLSWVFVKVMNYKVIGGVVFGVIALGMAIYNRNRIINENKKLSIEE"
     gene            30134..30607
                     /locus_tag="KRH23_002134"
     CDS             30134..30607
                     /locus_tag="KRH23_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5225412.1"
                     /translation="MKKYKYDSKRYLLSVTIPGFFMILILIYALFNNYTNFNLNIYSL
                     LIIVCTYGIFNTFISSSNPKKIIIDSKCIHFTSFMTTHKYEIKDIEKIRIREFYNKKI
                     YLKINDGNLFKGRYWIRTNMFNNSIALYSYFIELEECLYPDSLKFRNKKFENKNI"
     gene            30779..31429
                     /locus_tag="KRH23_002135"
     CDS             30779..31429
                     /locus_tag="KRH23_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HHS5225413.1"
                     /translation="MLLEKLRKEVLQASLDLLNYNLVTLTGGNVSGRDEQTGYIAITP
                     SGMDYRNLTPSDIVIVDVDGNIIDGKWKASVDLSDHLYIYKHREDINSIIHTHSTYSS
                     CFAILNEPIECASTTLANEVGGSVPVAKFSPPTSKKMGKCVIEAIGDKRACLLANHGV
                     IAVGPSVGHALTAAVMLEDSAKVYYLAKSIGTPVLLPDEEIQRARDVFFNVYGQDK"
     gene            31603..32535
                     /locus_tag="KRH23_002136"
     CDS             31603..32535
                     /locus_tag="KRH23_002136"
                     /EC_number="2.3.1.-"
                     /EC_number="6.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009107 - lipoate biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009249 - protein lipoylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HHS5225414.1"
                     /translation="MYYLLNKSTNPYFNLALEEYLFLNDKYNDDIIIIWRNEESIFIG
                     KNQNPYQEVYHDVIEKGEIPILRRISGGGTVYHDLGNINMSFIQKDRQLHEIDFLEHT
                     KFMQKMLSTLGLDVSITERKDLFLNGKKISGSAQSIKRKNSLYHGTLLYDSDLNKLTK
                     YLNSNKATESNATKSVSSKVTNIKFLLEKDINYFLDYCVEYLKSNIKNIKELELDEED
                     IKSVYNIGEDKYKKIEWTYGKTPKFQVVLPFNNESKINIHVNRWKVSKFFISYDDNVI
                     NMDKLLDLNFFKEEIKESILENYPHYIDLINLIF"
     gene            32809..33522
                     /gene="ispD"
                     /locus_tag="KRH23_002137"
     CDS             32809..33522
                     /gene="ispD"
                     /locus_tag="KRH23_002137"
                     /EC_number="2.7.7.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050518 - 2-C-methyl-D-erythritol
                     4-phosphate cytidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019288 - isopentenyl diphosphate
                     biosynthetic process, methylerythritol 4-phosphate pathway
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HHS5225415.1"
                     /translation="MYSVIIVAAGSGRRMNLDINKQFIKLREKEIIAHTIQVFYENIN
                     IDEIVVCIKKEEEDFFKENIINKYNFKNIKIAYGGKERQDSIYNGLKKLDKNCDIVLI
                     HDGARPFVDHRIINESIKVAKEKKAVVVGVPVSDTIKIVSDGTVQETPERNLLWAAQT
                     PQTFEYNLIIDAYEQAYKNNYYGTDDSMLVENIGQSVTMVMGSYENIKITSPEDLNIA
                     EQILNMEKRDEVNSRRRII"
     gene            33519..34004
                     /gene="ispF"
                     /locus_tag="KRH23_002138"
     CDS             33519..34004
                     /gene="ispF"
                     /locus_tag="KRH23_002138"
                     /EC_number="4.6.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008685 - 2-C-methyl-D-erythritol
                     2,4-cyclodiphosphate synthase activity [Evidence IEA];
                     GO_process: GO:0019288 - isopentenyl diphosphate
                     biosynthetic process, methylerythritol 4-phosphate pathway
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 2,4-cyclodiphosphate
                     synthase"
                     /protein_id="HHS5225416.1"
                     /translation="MRIGLGYDVHKLTEDRKLIIGGVEIPHDKGLLGHSDADVLIHAI
                     MDSILGALALGDIGKHFPDTDEEYKGADSMKLLEHVYNLITSKGYKIGNIDSTIIAQS
                     PKMAPYIESMRSNISKVLNTDIDNINIKATTEEGLGFTGAKQGIASQSICLLLLTSQN
                     N"
     misc_binding    34099..34307
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            34371..36086
                     /locus_tag="KRH23_002139"
     CDS             34371..36086
                     /locus_tag="KRH23_002139"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0002161 - aminoacyl-tRNA deacylase
                     activity [Evidence IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0004827 - proline-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA];
                     GO_process: GO:0006433 - prolyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HHS5225417.1"
                     /translation="MKMSKMFMPTLKEIPADAEITSHQLMVRSGMIKKMTSGVYNQLP
                     MGLRVFKKIEQIIREELNKKDCQEILCAALLPSELWKESGRWTAMGEEMFRLKDRTER
                     EYCLGPTHEEAFTDIIRQEITSYKQLPLNLYQIQVKYRDERRPRFGVMRTKTFTMKDA
                     YSFDVDDKGLDKSYQDMFDAYVSIFDRCGLENSPVQADSGAIGGSTSAEFMVKSEVGE
                     DEVVFCSGCDYAANVERAESCNLASQKEEMKELEEVHTPGAATIKELEEFLKTSPDKF
                     AKTLVYEADGKTVVVVVRGDREVNEIKVSNAIGSVIEFALATDDVVRKVTNAEVGFAG
                     PIGINADYVFIDKEIVEQRNIVVGANKTEYHIKNANYGRDFEGIVGDFRNVQEGDKCI
                     VCGKPLEIARGVEVGHIFKLGTKYSESMNANFIDKDGKSKPIVMGCYGIGVERTAAAI
                     IEQHNDEKGIIWPLSVAPYHVVIVPANMKNEEQISIAENIYNDLQAMGVEVLLDDRDE
                     RIGVKFNDSELIGIPMRITVGKNINEGKVEFKLRHKEDKEIIDIEEINEKVKAEFIRN
                     NVRLG"
     gene            36208..37653
                     /gene="proS"
                     /locus_tag="KRH23_002140"
     CDS             36208..37653
                     /gene="proS"
                     /locus_tag="KRH23_002140"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004827 - proline-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006433 - prolyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HHS5225418.1"
                     /translation="MAKNEKQFVEEITKMEDDFPQWYTDVITKTDLVDYAPVKGFMVV
                     KPYGYALWEKMQEFMDKKFKETGHKNCYFPLLIPESLLNKEAEHVEGFAPEVAWVTHG
                     GNKKLEERLCVRPTSETIICTMYAKWLKSYRELPYLYNQWCSVVRWEKSTRPFLRTSE
                     FLWQEGHTLHETAEEAQEETIQQLEVYKALCEELLAMPVVAGQKSESEKFAGGERTYT
                     IEAMMHDGKALQSGTSHFLGQHFTKAFDITFADREGNLANPYHTSWGASTRLIGGLIM
                     THSDNRGLVLPPRVAPIQVVIVPIAAKKGNVMETVDKIYADLKAKGVAVEVDDRDNYT
                     TGWKFNEWEMKGVPVRVEIGPKDIENNQAMVFRRDTLEKDSMPLEGLADAICDLFDVI
                     HNDMFEKARKHREDNTSIVENMDEFRKALEEKPGFIKTMWCGDAECEAKIKEETGATI
                     RCLPFEQENLGHKCVYCGKEADSMVVMAKAY"
     gene            38091..39572
                     /gene="gltX"
                     /locus_tag="KRH23_002141"
     CDS             38091..39572
                     /gene="gltX"
                     /locus_tag="KRH23_002141"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004818 - glutamate-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HHS5225419.1"
                     /translation="MNVRVRFAPSPTGFVHIGSLRTALYNYLFAKKMGGEYILRVEDT
                     DQSRLVEGAIENMLNAMKWAGVNHSEGVILDDSGKVVQKGEYGPYIQSQRLDIYQEYI
                     KQLLDSGKAYYCFCTKERLDEVRDAQRAAGETAKYDGHCKNLSKEEVEANIKAGIPYV
                     IRLRLPENHTIKFTDLVRGDMEFNTNDLDDQVLMKTDGFPTYHFAVVVDDYLMKITHV
                     IRGEEWVSSTPKHVYLYEAFGWEAPVFVHLPNILNKEKKKLSKRQGDVAVEDFKKKGY
                     LPEGLVNYVALVGWSPEDNQELFTMEELEKAFSVERVSKSGGVFDTEKLNWVNQHYIK
                     DGDDAYLTDLAIPFLIEDGFITEEEATNKYDFLKSMISVLKEKLQYVKEVTEHASIFF
                     GDKIEVETEEGREFLRLEHIPTLIDALREKIEKTEVLNAEFVQAMLKEIQKEYKIKGK
                     NLFMGSRIILTGQMHGPDLPKVMEVLGKETCLNRIAYVKNNIL"
     gene            39793..39948
                     /locus_tag="KRH23_002142"
     CDS             39793..39948
                     /locus_tag="KRH23_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5225420.1"
                     /translation="MYSNIDDVKKELKELCLEYVTILEKLKDEKMITEETFEKCSSQK
                     KIFLEEQ"
     gene            40093..41490
                     /gene="cysS"
                     /locus_tag="KRH23_002143"
     CDS             40093..41490
                     /gene="cysS"
                     /locus_tag="KRH23_002143"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004817 - cysteine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006423 - cysteinyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HHS5225421.1"
                     /translation="MKVYNTLTRTKEEFVPLEEGKVKMYVCGPTVYNYIHIGNARPFI
                     IFDTLRRYLEYRGYDVTYVQNFTDVDDKIINRSHEEGISPEEVAAKYIKEYFVDCDGL
                     GIKRATVHPQVTDNIQQIIEFIKELEDKGYAYAVNGDVYFDTNKFEGYGKLSGQKQED
                     LEAGARIEVNDQKRHPMDFVLWKAKKEGEPGWDSPWGEGRPGWHIECSVMSKRYLGET
                     IDIHAGGQDLTFPHHENEIAQSEARSGKTFSKYWMHNGYININDEKMSKSKGNFFTVR
                     DISKLYDLEIVRFFMLSAHYRNPVNFSDEMLNQAKAGLERLYNTKEKLEFTLSNLVES
                     PLTEKEVELVKELDDFRQKFIDAMDDDVNTADAVSVIFELAKLINSNVDENSSLEFAK
                     KCLDEFNELTGVLNIVNKKKDTVLDKDIEELIQKRTDAKKNKEFQLADDIRQQLLDMG
                     IVLEDTRQGVKWKRI"
     gene            41493..41888
                     /locus_tag="KRH23_002144"
     CDS             41493..41888
                     /locus_tag="KRH23_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HHS5225422.1"
                     /translation="MEKTELVTMSPLVLAYLGDTVYETYIREYLIRQNTQRKVNDLHK
                     LAIKYVKAKAQATIIHEIEIELTEEESKIYKRGRNQKSNTSPKNADIIDYKHATGFEA
                     LVGYLYLNNEIERLQYIINKGIKIIERDM"
     gene            41994..42752
                     /gene="thyX"
                     /locus_tag="KRH23_002145"
     CDS             41994..42752
                     /gene="thyX"
                     /locus_tag="KRH23_002145"
                     /EC_number="2.1.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0050797 - thymidylate synthase (FAD)
                     activity [Evidence IEA];
                     GO_process: GO:0006231 - dTMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent thymidylate synthase"
                     /protein_id="HHS5225423.1"
                     /translation="MKVKLISHTPEPEKVIAMAAKLCYSPVGTDEIEKDLTDESIEKF
                     LNMLLSIGHGSILEHASFTFSIEGISRACSHQIVRHRIASFSQQSQRYVKLEQFEYII
                     PPEIEKIEKAKELFIDSMKKDQENYDKLVEILFENHYNDLIKNGKNEKTAKRQAEKKA
                     IEDARYVFPNACETKMVFTINARSLFNFFEHRCCERAQWEIRNLAVEMLREVKKVAPI
                     LFKKTGPSCVNGSCPEGTMTCGDIVQVREKFKAL"
     gene            42765..43502
                     /gene="rlmB"
                     /locus_tag="KRH23_002146"
     CDS             42765..43502
                     /gene="rlmB"
                     /locus_tag="KRH23_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HHS5225424.1"
                     /translation="MASIEGRNPVIEAIKSDREIDKILIANSAKEGSIKKIIGMAKDK
                     NIIIQYVDKHKLDEVSTSHSHQGVIAYASEYKYYELDELIDLAKNKDEDPFFIILDEI
                     TDPHNLGSIIRTADAVGAHGVIIPKRRSVHITPVVAKASAGAVEYMPVCKVTNIVNTI
                     KRLKEEGLWIAAADMDGETFYKQNLTGPLGVVIGSEGFGISRLVKQNCDFIVKMPMIG
                     NVTSLNASVAGGILLYEIFRQRLDKSK"
     gene            43505..44032
                     /locus_tag="KRH23_002147"
     CDS             43505..44032
                     /locus_tag="KRH23_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HHS5225425.1"
                     /translation="MKKNINHYLIIDGYNIINAWDNLKELAKEDLEDSREKLIDDIIE
                     FSEFMGYKTIIVFDAYNVKNSREKVEKRKHITIVYTREHQTADSYIEKFITSLSKYDD
                     VKVATNDYAEQQMILGKGATRMSARELKLELDRSKNKMKEKNIGLRKKIQRNWLEERL
                     DKETLSKLENIRRKR"
     gene            44097..44744
                     /gene="sigH"
                     /locus_tag="KRH23_002148"
     CDS             44097..44744
                     /gene="sigH"
                     /locus_tag="KRH23_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sporulation sigma factor SigH"
                     /protein_id="HHS5225426.1"
                     /translation="MLVAKEKSYELVDNCQQDEYNIVLRASEGDKIALEYIITKYRNF
                     VKAKAKSYFLIGADKEDIIQEGMIGLYKAVRDFDGSKTNSFKCFAEICITRQIITAIK
                     TATRQKHIPLNSYVSLNKPIYDEESDRTLLDIIATSIVTDPEELIISKEELKNIESKM
                     NELLSDLELEVLELYLNGKSYQFIADKLKRDVKSIDNALQRVKRKLEKHLENRND"
     gene            44818..>45046
                     /locus_tag="KRH23_002149"
     CDS             44818..>45046
                     /locus_tag="KRH23_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HHS5225427.1"
                     /translation="MAKAKYERTKPHVNIGTIGHVDHGKTTLTAAITKTLYDRYQLGE
                     AVDFANIDKAPEERERGITISTAHVEYETPNR"
BASE COUNT        18719 a         4649 c         8463 g        13215 t
ORIGIN      
        1 ggtaaggcag tggactgcaa ctccttgatc cccagttcga atctgggtgt cgcctccaat
       61 aaaatgcgct catagctcaa ctggatagag tgtctgacta cgaatcagaa ggttaggggt
      121 tcgagtccct ttgggcgcac catatgaata gcgagggatt atagctcagc tgggagagca
      181 cctgccttac aagcaggggg tcacaggttc gagccctgtt aatcccacca gtgcaaacct
      241 ctagtaaaac tactagaggt tttatttttg attgaaaaag tttttatatt taggaggtaa
      301 aaaatttgta tatagtaata ggaaatgaaa tagttgatag tgaagaactt aaaataatta
      361 tagataaaaa tagtgaattt aaagttgaaa aagatttaag taaaagcaca aaaagagaag
      421 atgtaatagc atatcagtta agtatagatt taaattacct agattctctt ataaatgagc
      481 aatgtaattt agccagtcta tctgatgaag agaaatttga tgaatatatg actttgtctg
      541 atgaacttgc actggattta gaagagttaa tgccaaaata tacaataata aatgctagag
      601 catataaatt agacgaggta gatggaattg taaaaataat actagctgta gcgtatgcag
      661 atttagggca cttaaaactt tctgatgtag taaagaggct atctagacaa gtagattagg
      721 atatgaatat gaactatatt aaaaaaatgt ataaaatctt acgtaaagat gaaaataatt
      781 atgtaaacat agaaaaaaac agtataaaat caagtcaatt gtagaaattt tcacataaat
      841 tcatctgaaa ttctataaaa aatgccttaa ttttaatgag gtaaatcgag tttacacagt
      901 ctaaaaatta cttatattta taaatttatc ttattaatta aggaactttc ttaaacatct
      961 tcaaaaataa agtattttag tctataatct ttaatattac acaaacaata aaggagaaga
     1021 atagagtatg cttaaaaagt ttaataaaat actagtggct aatagaggcg aaatagctat
     1081 aagaatattt agagcctgtt cagaattggg gataaaaagt gttggtatat acagtaagga
     1141 agataagtat ggattgttta gaacaaaagc ggatgaatca tatttgatag gagaaggtaa
     1201 agggccaata gatgcatatt tagatatgga tggaataata gacctagcaa agagaaaaaa
     1261 agttgatgct atacatccag gatatggttt tctagcggag aatgcagaat ttgctcgtaa
     1321 atgtgaagag aatggaatta cttttatagg accatcatct aaggtaatga atatgatggg
     1381 ggataagatt aactctaaaa aaatcgcaaa agaagttaat gttcaaacta taccaggagt
     1441 agaaaaagca ataagaagta ctgaagaagc aaaggaagtt gcaaacaaaa taggatatcc
     1501 tgttatgata aaagcatcta atggcggtgg cggtagaggt atgagaattg tacatcgcga
     1561 agaagactta gagcttgaat atgaaactgc ttgtagtgaa tcaagaaaag cttttggaga
     1621 agatattata tttatagaaa aatatatagc tgatccaaaa catatagaag ttcaaatatt
     1681 aggtgataat tatggaaata tagttcactt atatgaaaga gattgttcag ttcaaagaag
     1741 acatcaaaaa ataatagaat atgcaccagc tttttcgtta gatgataaag taagaaaaga
     1801 gatatgtgaa gatgcagtta agttatcaaa acatgtgggt tattctaatg cgggaacatt
     1861 agaattttta gtagatgcaa atggtgggca ttattttata gagatgaaca caagagtaca
     1921 ggttgaacat actgtaacag agatggttac aggaatagat atagttcaaa gtcaaatact
     1981 aatagcccaa ggttacagct tagatagtga agaaattaat ataaaatcac aagatgatgt
     2041 ggaaataaga ggttactcta tccaatgtag aataactaca gaagacccta agaataaatt
     2101 catgcctgat acaggtaaaa ttcaagttta tagaactggt tcaggatttg gtataagact
     2161 agatggagga aatggattta caggggcaaa cataagtcct cattatgata gtttattggt
     2221 taagacaata tcttgggata gaacattcca aggagcaata aataaaacta taagatctat
     2281 aaaagaactt agagttagag gtgttaaaac taatgtagga ttcctagtta atgttttaaa
     2341 taatcctata ttctcaaatg gtaaatgtag tactaagttt atagatgaaa atccagattt
     2401 atttgaaata acagaaagta aagacagagg aacaaaatta cttcaattta taggagatgt
     2461 aattgtaaat gataatgctt gtaaagaaaa accattattt gatgcattac atgacccaag
     2521 aatggataag gatggttcaa aatcggaagg aagtaaaata cttttcgata agttaggtaa
     2581 atctgcatat atagaaaaga taaaaaatga taagaaatta ctattaacag atacaacaat
     2641 gagagatgca catcaatcat tattagcaac aagaataaga acatatgact tattaaaagc
     2701 tgctaagcca acagaaaaat atcaaaagga tttattctca cttgaaatgt ggggaggagc
     2761 tacttatgat gttgcatata gatttttaaa agaatctcct tggcgtagat tacaaaagct
     2821 aagagaagaa ataccaagca taatgttcca aatgttgctt agagcatcaa atggagttgg
     2881 atataaaaac tatccagata atgtaataga agaatttaca aaagaatctg ctagacaagg
     2941 tatagatgta tttagaatat ttgattcatt aaactgggtt gaaaatatga aaccatctat
     3001 taatacagct ttagaaactg gaaaaattgt tgaagcaact atgtgttata caggtgatat
     3061 actagataag actaaaacta aatacaatct agaatattat attaaaatgg cacaagaatt
     3121 agaaagcttg ggagcagaca taatagcaat aaaagatatg tcaggtcttc ttaaaccata
     3181 ttcagcttac acactagtta aagagttaaa gaaaaatgta aaagcaccaa tacatttaca
     3241 cactcatgat acaagtggaa atggtgtagc aacttgttta atggcgtcag aagctggagt
     3301 agacataatt gatgctgcat tagaatctat ggcaggactt acaagtcagc catcacttaa
     3361 tgctatagta gaggcactta agaatacaga gagagataca ggaatagatt tatttggata
     3421 tgatgagtta ggaaaatatt ataaggattt aagaaaagtt tataataaat ttgaaagtga
     3481 tttaactaat tcttgtgcag aaatatataa ttttgaaata ccaggaggcc aatatacaaa
     3541 cttaaaacct caagctgata gtttaggatt agttaataga tttgatgaag ttaaagaaaa
     3601 atataaagaa gctaatgaag ttgtaggaga tataataaaa gtaactccat cttcaaaagt
     3661 tgtaggagac ttagctatct ttatgactaa aaataaatta gataaagaca atataataga
     3721 agaaggtaaa aatttatcat tcccagattc tgttgtggat tactgtaaag gtatgattgg
     3781 tcaaccagaa ggtggaatac caaaagattt acaagaggta gttctaaaag gtgaagaagc
     3841 tataacagta agaccaggtt cattattacc agcagaagat tttgatgaaa tagctaaata
     3901 tctaaatgaa aagtatgata taaatgctaa tataagaaat gttataagtt atgctttata
     3961 tccaaaagta tatgaagatt atatcaaaca tctacaacat tataatgata tatctaaact
     4021 tgaaagtgat gtattcttct atggattaaa taaaaatgaa gaatgtgaag tagaaataga
     4081 agaaggtaag gtattaacaa taagattagt tgaaattggt gaagttaagg aaaatggatt
     4141 tagaactata ggatttgagt taaatggaat ggttagagaa gtagaaataa aagataagaa
     4201 tttctctgga aaaattaata atgttgaaaa agctgatatg aatgaccctc ttcaaattgg
     4261 agcaagcata ccaggaaaag ttataaaaat aatggttaaa gaagaagatg aagtaaaagc
     4321 aaatcaacca ttaatcgtta tagaggctat gaagatggaa actataatag ttgctaagac
     4381 tgatggagta attaagtcaa tcaaagtaaa agaagatgat atggttgaag ataaacaatt
     4441 attaatgata atgaagtaat ttaattaaaa taaattaaaa agcactctga aatgtttaat
     4501 aaaaaatgtt ttagagtgtt tttatttatt ttaattaaat atttgttaaa aaaaagagga
     4561 caattacctc cagatgtaga aataaagcta gtaaggaaaa tgttatctaa aaattctaaa
     4621 tatagtaaat attttccata atatttctta ggaaataaca gcaaagataa aatacataaa
     4681 tttaaaaggt gggtgcttat atgaaggttt atgatagtaa aatgttgaga aatgtagcgg
     4741 tattaggaca tagcggatgt ggaaaaacaa atctaatcga aactatagct tacacagcaa
     4801 acactaataa gatacctaaa ttaacagaca aggtaaatat gacttatagc atgggattaa
     4861 tacctataga gtataatgat tataagttta acttattgga taccccagga tattttgact
     4921 ttagcggaga cgttgtgtca tctcttagag caagtgatgc agcaataata gtaatagatg
     4981 caacagcgcc tattcaagtt ggtacagaga aatcattaga actaactgag agtattccta
     5041 agataatgtt tataaataaa atagataatg aaaaggcaag atacaaagat gcaatagcaa
     5101 tgttaagaga aaaatacaat aataagatag ttcctatgat aagtcctata tacaaagata
     5161 aaaactttgt aaagttacat aatgtttttg aaaacataga tgatttagaa ggtgaattta
     5221 aggaacaagc tatgagtgtt aaagaagcat taatggaact tatagcagaa actgatgacc
     5281 aaatattaga taaatatttt aatggagaag aactaactac agaagagata caaaaaggta
     5341 ttattatagg tatacaaaga ggtgatatta tacctgtaat atgtggttca actataaata
     5401 atataggcac aaaggaaata ttagatacaa tatcaagtta tttagaacct atctttacag
     5461 aggaaagcaa accatttagg ggattagtat ttaaaactat ggttgaccca tttgttggaa
     5521 agatgtcata tataaaaatt actgagggtg tactttctaa ggataaagat gtttttaata
     5581 taaataaaaa tgtaaaagaa aaaatagcta atatatatac attgagaaat agtgaattag
     5641 tagaaataga aaaagctaaa gctggtgata tagtagttat aactaaagtt aattctctaa
     5701 aaacaggaga cactatatct gcagataaag atgcagaagc tttagaaaag atagattttc
     5761 ctaaaccaca aatatattat gcagtaactc ctaagaataa aggtgatgaa gaaaaagtag
     5821 catctgtatt aaataaacta gtagaagagg accctacatt acattggtat agaaatacag
     5881 agacaaaaca agcactttta ggaggtcaag gagaacttca tataaaaaca attaaaaata
     5941 aaatgaaaga taagtttggt gttgatgttg aattgaatga ccttaaagtt ccttatagag
     6001 aaactataaa aggaacagct gatgtacaag gaaaacataa aaagcaatca ggtggtcatg
     6061 gtcaatatgg agacgtaaaa ataagatttg aaagatgtga atctgatttt gaatttacag
     6121 aagaaatatt tggtggttct gtaccaaaac aatatatacc agcagttgaa aaaggtttaa
     6181 aagactctat gcaaaaaggt atattagcag gatatcctgt tacaaacata aaagctacgc
     6241 tttatgatgg ttcataccat gatgtagact cttctgagat ggcctttaag atggcagcaa
     6301 gtgcagcctt taaaaaaggt atggaagaag cacacccaat actactagaa cctataatga
     6361 aacttaagat aactgttcca gaagaatata tgggagatgt catgggtgat ataaataaga
     6421 gaagaggaaa aatatttgga atggaaccag atgacaaagg gaaacaaata atatttgcag
     6481 aagctccaca agcagagaca tttaaatatg caatagattt aagagcaatg acacaaggta
     6541 gaggatactt tgaaatggaa ttagagagat atggagaggt tccatcacag tttgcagaaa
     6601 aaataattgg gttagctact gcaaagtaat gaacaaaata aatagaaaaa taattaatat
     6661 atattattaa aaatattttt agggttttaa ctaggtatag gtttatgtta ggtaaactta
     6721 tacctagttt ttatacattt ttgatgaata aaaaaatata taatactttc ttaaatattt
     6781 taataaaaag aaagtatttt tttattatta tttttacaaa tgtttagtaa taaagatgag
     6841 aaggtatatt taaaatataa agtatttaaa gttctgaaat ctaatcatga agcaaaaaat
     6901 tagcatttgg ttatcaataa atataataaa taaaaactca taattaatga aagaataaat
     6961 tcatatctaa atttctataa aaaatttaaa tttatacaat ttagggcttt aaaaatttaa
     7021 ataataggtg taaaataata gtcaaagaaa gtcaaaaata aaaaggtgtg tggtgatatt
     7081 aatggcaact atgacagata taattgaaaa atttattaaa gatttgatgg aagaagataa
     7141 tagcatacaa attcaaagaa atgaactagc aaacttgttt agttgtgcac catcacaaat
     7201 aaattatgtc ttaacaacaa gatttacaat agatagagga tattacattg aaagtaaaaa
     7261 aggtggcgga ggatatgttc aaatagaaaa aatacgaaaa agtaaagatg ggcatattag
     7321 agaactacta aatgaaaaaa taggaagtca gatatcctat aaaaaagcaa aggaattatt
     7381 agaaggttta aaagagtcag atttgattaa cgaaagagaa ttaaaattaa tattatatgc
     7441 aatagatgat aaatcattgt gtatgccaat atatgaatta aaagagaagg taaggtctaa
     7501 tattttaaag aatataataa taggattatt tagtatagag gagtgataat ttatgctatg
     7561 tcaaaaatgc aataagaata aagcatctgt atattataat aagatagtca atggagaaaa
     7621 aacagagatg tatttatgta gtgagtgtgc aaaagagaat acagaaatga attttaactt
     7681 agatatgcct ttttcaatga tggatatatt ttctaattta ggttttcaac ctaaaaaaga
     7741 acttgaggaa aagctagttt gtcctaaatg caatacaaca tatagtgagt ttaagaataa
     7801 tgggagattt ggatgtagtg aatgttataa tgcatttagt agtcaagtaa atccaatgct
     7861 tcaaaatata catgggcata tagaacatac aggaaaagca cctaaaaaat ctttttataa
     7921 gataagtgta gaaaatgaga ttaaagaact aaaagaagat ttagatagag ctataaaaaa
     7981 tgaagagtat gaattagcag ctcaatttag agataaaatt aaatatttaa aaggttctat
     8041 tgactaagat tggagtgata ttatgaaaga gaacatagtc atgaaatcaa gagttaggct
     8101 agctagaaat ttaaataact atccatttcc aaataaatta gataaagaat gtgccatgga
     8161 aataatagaa aaagtaaaaa atgcgtttat taattctaac ttagaacaaa aagaagaatt
     8221 tgatttctat aaaattgaag atttagacca atctaaaaaa atgcttatgg ttgaagaaca
     8281 tataataagc ccagatttag cagaaaatga taaaagtgca gttatagtaa aaaaagataa
     8341 aactataagc ataatgataa atgaagaaga ccatataagg atacaaacta tatgtgatga
     8401 tttaaactta gaatatgcat atagtgtagc aaatgaaata gatgatttgt tagaatcaag
     8461 tttagaatat gcctttaaca caaagctagg ttatctaaca tcttgtccaa ctaatacagg
     8521 aacaggaatg agagcttctg taatgatgca tttaccagca ttaagtcaac taggctatat
     8581 ggatgaactt tataaaattt catcacaaat aggtatagca attagaggga tatatggaga
     8641 acgaacagaa gcattgggaa atatatatca aatatctaat caacttacac ttggaagaac
     8701 agagtctaat attatagaaa atgtaagtgg acttacaaaa gatgcaattt caaaagaaat
     8761 aaaagctaga gaaatattgc aaaaaaaatt aggtataaaa ctagaagata aaatatttag
     8821 atcgataggg acacttgaaa attcaagagt aatgagtagc tcagaggcaa tgagccatct
     8881 atcaaatata aaaatgggaa tagaaatgaa ctatatagat aaactagatt taagggctat
     8941 agaacaactt atgataggta tacaaccagc gcatcagtca ataatgtata agagtgatga
     9001 tgttgagaat agagatataa atagagcaac atatattaga gaaactttgg aaaaattaag
     9061 aggagggatg aattgtgaac ttcaatagat ttacacaaag agctaaaaag gcaattgatt
     9121 tagcgtttga atctgctaaa agtctaggac acaatattgt cggaagtgaa catatacttt
     9181 taggtctttt aagagaagaa gaaggtatag ccgctaaagt tctaagtaaa gttggattta
     9241 cagaagctta tttagaaggc aaaatagttg atatggaagg taagggagaa gaaatctcag
     9301 aagatatagt attaagtcca aggagtaaac aaatacttga attatcagga atgtttgcaa
     9361 ataaattaaa aacaaattat attgggactg agcatatatt attagcaatt attcaagaag
     9421 gtgaaggaat agctaataag attttaaatt atgctggagt aaatgatagg actttagccc
     9481 aattaacaat tgatatgatg ggtattagtg ataaaaatca atacaaagca gaaaatagtt
     9541 acacgggcaa ccagaatcaa gcagaatcta aagtacttga taagtatgga agaaatctta
     9601 cactatatgc aaaacagaat aaaatagacc ctgtaatagg tagagaaaaa gaaatacaaa
     9661 gagtaataca aatattaagt agaagaacta aaaacaatcc agtgttgata ggagacccag
     9721 gtgtagggaa aacagccata gctgaaggtc tggctacaaa tatagcctta ggaaatgttc
     9781 cagaaacact aaaaaacaaa actttatact ctttagagat gggttcatta ttggctgggg
     9841 ctaagtatag aggagaattt gaagaaagaa ttaaagaagt tgtagatgaa gttgttaaaa
     9901 atggaaacat aatcttattt atagatgaga tgcacacaat aataggggct gggtctactg
     9961 gagaaggctc tatagatgct tcaaatatat taaagccagc cttagcaaga ggagaaatac
    10021 aagttatagg tgcaactaca attgatgaat atagaaagca tgttgaaaaa gattctgctc
    10081 tagaaagaag attccaacca gttatggtag atgaaccaac taaagaggac tcaataaaaa
    10141 tattagaagg attaagagat aaatatgaag ctcatcataa agttaaaata actgatgatg
    10201 ctataaaggc agctgtagaa ttatcaacta gatatatatc agacagatat ctgccagata
    10261 aagctataga cttgattgat gaagctgcat caaaagtaag attaaaagaa aatacacctc
    10321 cttcagaaat aaaaaaatta gaactagaaa tagaaaatat agataaagaa aaagaagaag
    10381 cagtaagatg tcaagacttt gagaaagcag ccaaaataag agatgaacaa ggtctactta
    10441 aaaaacaatt agaagatgtt agagaaagat ggaacaagtc atctaaacat tcagatttag
    10501 ttgatggaga agttattgct gaagtagtgg gcttatggac aggaatacca gttaataaaa
    10561 ttcttgaaga agaggctgat agacttttga gacttgagga aatactgcac aatagagtta
    10621 taggtcaaga acaagcagta aaatctattt caaaggcaat cagaaggtca agagcaggtc
    10681 ttaaagaccc taatagacca attggttcat ttttattttt aggtccaaca ggagtaggta
    10741 aaacagaatt atctaaggca ttagcagaag tgcaatttgg agatgaaaat caaataatta
    10801 gaatagatat gtctgaatat atggaaaaac atgctgtgtc aagaatgata ggttcacctc
    10861 caggttatgt aggtcatgat gaaggtggtc aattaactga aaaagtaaga agaaatccat
    10921 attcagttat cttatttgat gagatagaaa aagctcatcc agatgtattt aatattctgt
    10981 tacaaatttt agatgatggt agactaactg attcaaaagg aagaactgta gattttaaga
    11041 atactattgt aataatgaca tcaaatgttg gagcatctac aattggtaga caaaaaactt
    11101 taggatttag tatagctaaa ggagacgaag aagaaaaatc tcaatatgaa aaaatgaaag
    11161 aaaatataat gggtgaatta aaacaaagat tcagaccaga gtttttaaac agaatagatg
    11221 atataattgt tttccactca ctaaatgaaa atcatatatc aaaaatagta cttttaatgg
    11281 cagcgaaact acaagagaga ttaaaagaaa tggatataaa attagaaatg agtgatgagg
    11341 ctgttaaatt aatttctaaa tctggatttg acttagaata tggagcaaga cctcttaaaa
    11401 gagctttaca aaaagagttg gaagatgagc tatctgaagc aatcttaaaa ggtaatgtga
    11461 aaaagggaag taatgtagta gcaaaagtca aagatgaaaa aatagttttt gaaactaaat
    11521 aatttaatag agttgcattt taaaatattg caaatataag ttttataatc taaacaaaat
    11581 tttaagggca atgaatctat aataattcat tgtccttaat tattttattt aatctttaca
    11641 tattgtcttt cagatatgct aaaattatag tatagaataa aaaattaagg atgataaaag
    11701 tatggcaaaa ataaaaacaa aatatgtatg tcaatcttgc ggatatgaaa cagctaaatg
    11761 gcttggtaaa tgtccagaat gtacaaaatg gaatacattt gtagaagaaa tagaccaaaa
    11821 aagcaccaaa aaagaggtct ttataataga taaatcttca tctaaaccag tcagtataaa
    11881 ctcaatagaa agtaaagaag aagagcggtt tacaacagat ataaatgaat tagatagagt
    11941 gcttggagga ggtatagtta aaggctcttt agtgcttgtt ggtggtgacc ctggtatagg
    12001 taaatcaaca cttttaatcc aagtatctag taatgttgcc aatttaggaa aaactgtttt
    12061 atatataact ggagaagaat cagaatctca aataaaaatg agagcaaaaa gattaggtat
    12121 taactcagaa aatttatata tatttgctga aaataattta agtataattg aatcttattt
    12181 agaaagtgta aatccagaat taataattct agactcaatt caaactgtat tcagtccaga
    12241 aatatcctcg gcaccaggaa ctgtcagcca aattaaagaa ggtacttcaa aattcatgaa
    12301 aatttctaaa aaaatgggaa tttcaacgtt catagttggg catgttacaa aagaaggttc
    12361 actagcagga ccaaaattat tagagcatat ggttgatact gttctatatt ttgaaggaga
    12421 aagatataat acttatagat tagtaagagc tgttaaaaat cgatttggtt caactaatga
    12481 acttggagtg tttgaaatga gggatttagg attagtagaa cttgataatc catctaaaat
    12541 tttaatctct gaaaaaccaa aagatgtagc aggttcagta ataatatcta ctgtagaagg
    12601 tacgagacca atgttacttg aattgcaagc attagtttct cctacaagtt ttggtatacc
    12661 aaaaagaaca tctacaggag tcgattacaa tagagtaggg atgttattag cagtattaga
    12721 aaaacgtgtt ggtttgcaaa tacaaaatca agatgtctat ataaacatag ttggaggaat
    12781 aaagataaat gaaccctcaa ttgatttagg gatagccatt tctgtagcat ctagttttag
    12841 aaatataccg atagatgaag atatagctgt tacaggagaa gtgggactta caggagaagt
    12901 tagagcagta agctttatag aaaaaagaat agctgagtgt aaaaaacttg gatttaaaaa
    12961 gatagtagtt cctagaagta attatgatgt tgtaaaagag accaaaggca tagaaatatg
    13021 gccagtagat aacttaagac aagctataaa tatagtactt gggaggaatc aataaatatg
    13081 gagaattttc tagataataa aaatatgcta tatgcattaa aaatgatatc tcctggaact
    13141 ccacttagat taggtctaaa caatgtacta agagctaaga ctggtggatt aattgtaatt
    13201 gcaacaaacg aagatgtaat gaaaatagta gatggaggat ttgctataaa tgcagaatat
    13261 tcaccatcat atctatatga attagctaaa atggatggag ctatagtttt aagtggtgat
    13321 gtaaagaaaa tattatttgc taatgcacaa cttatacctg actattttat agaaacatca
    13381 gagacaggaa caagacatag aacagcagaa agagtagcaa aacaaactgg tgctatagtc
    13441 ataggaattt cacaaagaag aaatgttata acagtttata gaggaaatga gaagtatgta
    13501 gtcgaagata tatctaagat atttactaag gcaaatcagg ctatacaaac tctggaaaaa
    13561 tataagacag tattggacca agctgtaaca aatttaaatg ccttagagtt taatgatttg
    13621 gtaactattt atgatgttgc attagtcatg caaaagatgg aaatggtaat gagagttaca
    13681 agtataattg aaaaatatgt gatagaattg ggtgatgaag gaactttagt aagtatgcaa
    13741 ttagaagaat taatgggtac aaccagaata gaccagaaat taatattcaa agattataat
    13801 aaagaaaaca cagaaataaa agaacttatg aaaaaggtca aaaatttaaa ttcagaagaa
    13861 ctaatagaat tggtcaatat ggcaaaacta ttagggtata gtggtttttc agaaagtatg
    13921 gatatgccta taaaaacaag aggttatagg attcttagca aaatacatag actaccaaca
    13981 gcaataatag aaaacttagt aaattatttt gaaaactttc aacaaatttt agatgcatct
    14041 attgaagaat tagatgaggt tgaaggaata ggtgaaataa gagcaacata tataaaaaat
    14101 ggactcataa aaatgaaaca attagtctta ttagatagac acatatgatg aattttaaat
    14161 gaattttact acttttttct tgaatataat atacactttg gtctataata gataagtata
    14221 actagggggt gaagcattga taaggaaagt aacaagaata ttgtttattt tacttggatt
    14281 tacaataggt ataacaacct atttaacatt aatgaaagat tttgaaatat taacatttgg
    14341 aaaagaaaca tatggttata tcgcagctgt agtagcaggt ataataatag ccattttagg
    14401 atatcttata gaaccatggg ttgtaaataa agtaaaagaa attgctaaaa tagtggataa
    14461 agaattgtca aaatatcctc agactgatat attgttaggg tctatgggtc ttatagtagg
    14521 atttgttatt gcgtatttat taagtggatt agtaaataga ataccaatag taggtggaat
    14581 actatcctta ctattatatt tattcctagg atatcttgga atgaaagttg cgcttaaaag
    14641 taaaaatgat ttatttaata ttggaaaact aggaagatta gcaaatccta ttaaggataa
    14701 agataaggat aaagaaaata aaaaagaagt aaaagccatt cctccaaaag tattagatac
    14761 aagtgtaata attgatggaa gaatagctga tatttgtaag actgggttta tagaaggaaa
    14821 acttattatt cctgcttttg ttttggagga actaagacat attgcagatt cttcagatga
    14881 tttaaaaaga gtaagaggta gaagaggtct ggatatatta aatataattc agaaagaatt
    14941 aaatatagaa gttgaaataa gtgagagaga ctttgatgat atagcagaag ttgatagtaa
    15001 attattaaag cttgctcagg ttttaaatgg aaaagttgtt acaaatgatt ataacttaaa
    15061 taaagttgct caattccaag gtgttgaagt attaaatata aatgagttag ctaatgctat
    15121 aaaaccagtt gctataccag gtgaagatat ggttgttcaa gtggttaaag aaggaaaaga
    15181 ggctcaacaa ggtgttgcat atctagatga tggaactatg atagttgttg atggaggaag
    15241 aaaatatatg aatgagacta taaaagtact cgttacttct gttcttcaaa ctcctgcagg
    15301 tagaatgata tttgcaaaac ctaaaaatta atatgttcaa agaaacctat aatttgggct
    15361 gtttatttta aatagatggt ccaaatttat ttatttataa cgataatgtt taatgtattc
    15421 ttaaagatgg ggatttaaat cagaaagcag ggagaattta tgagaaaaaa gattatatct
    15481 ttcttagcaa catttatcat aatattaaca tcagcaagtc agtatagttt tgcagatgat
    15541 atatcaacac gtggaaaagt aatatttata gatatgaata gaactagtat gagtaatatg
    15601 ttaagaataa aatcattaag agaagaacta gacaatagag ggtatattgg tttgatgaat
    15661 ataagaggcg ataaaggaag tgatgataga aggtcatatg ctagtatggg tgctggtggt
    15721 agagctaatg tggctaatga agaagatatt aattttgaaa gctcgagtaa ggatagaaat
    15781 atagtttttg aatcagctac aggaaaaagt gcaaaaggta taaataattt aactataaat
    15841 aagtctataa atgaaaattt aaactttgga gagtatggtt ctgtattagg gtcattagga
    15901 caaagtttat ctgataatgg attaaaagca tctgtattgg gtaattcaga tataattgaa
    15961 aatggtcaac ttataaaaaa tagaaactta tgtctaactg caatggatga atatggaaga
    16021 atacctaatg gaaatgtaga tactataaat aaaaaagact tatctatgcc ttatggaata
    16081 tcaactgatt atgataaatt gattgtagag actaaagaag cttacaaaaa taatgatgtg
    16141 atttttgtgg agcttggaga cacatataga ttagatttat ataaaccaaa tttaaatgaa
    16201 aaaacatatg agagtatgaa agataacata gaaaaaaata tagatatata tttaaaaaat
    16261 atattttcta tggttgaaga aaatgacact atctacatag caagtgcatt tccaagtgat
    16321 ttagattata aaaataaaag aagactttct ccaataataa aattaaatgg agaagggaaa
    16381 ggtatattat catcttcaac tactagaaga gaaggtattg taacaaattt agatgttggg
    16441 gttgaaatat tagacaactt taatataaaa aatcaaaata tggttggaag aaaatatgaa
    16501 cttattaaca gagatgataa taaagaattt ttgatggatg aatatcaaaa gatagtatct
    16561 atttcaagca taaggtctac aatactgaat ggttttgtaa gtatagtttt cttgtcatgg
    16621 atagttgcta tgattgcaat tttatttaga aagcatatat caaaaaatta taaagaaaca
    16681 acatttttta tattaaagga acttttaaaa ataggaatag taatgccact gtcatttatg
    16741 ataacaccaa taatgaattt caaaacacca ttagcaatat ctttaggaat aattataata
    16801 acacttacta tatatcttat aagtaaagtt ttaataaaga acgatttaaa aaacatgctg
    16861 ttttttactg gattaaccat agtaattatg gttattgatg ctgggtttgg ctcatattta
    16921 atgaaaagca atgttatgag ttatgactgt ataattggag ctagatatta tggagtagga
    16981 aatgagtatc aaggtgtggc aatcggtagt gcaatattta catttgcaat tttacttaca
    17041 tataaaaata taccaaagtg gtctataata gttttttctt tggttatctt aattacaagt
    17101 gcatctccaa ttatgggagc aaatgttgga agtgctattt ctgaatgtgt tgcattttta
    17161 ctatttatac tattgatata taatgtaaag atagatttca aaaaaatcgt attattaggt
    17221 atagcagtat tatttgtatt aggagttttt gtagcaatag atatgatttt gggaagtaat
    17281 tcacatttag gtatgtttgt aaaagaaatt tactttaatg gaccaggaga aataatacaa
    17341 acatttagta gaaagataga gatgaattta aagctagctc aaaccagtgc atgggtaaat
    17401 atactgttaa ctggaatagg tgtaatttta gttcttatga ttaatcagat tagatacttt
    17461 aagcaactga tggatgagta tccaattgta tttaaaggat ttatagcatc aatagcagga
    17521 tgtttagtaa ctcttttagt gaatgactct gggattgtat catcagctac agcctttatt
    17581 tatgtaattg tacctatgat aacattaagt ataaatctca cagcattaaa agaataagta
    17641 ctgtatgaat aatatgtgaa tatgaacaca ttaatttaac ttctttattt acaaaataaa
    17701 gaagaaagtt tataaaaaat aaattataat aaaaaagagt ttatctcaaa attgattatt
    17761 ctaatcaaat tttaaggtaa acttttttta ttataaagat aaataacata taacttcata
    17821 ttttaggtag attttttctt atatgtttag gagtgcattt aaatttttcc ttaaaaattc
    17881 tgtaaaataa ttttgtatta gtaaatccat gagcttctaa tatactgcat aaggtatcat
    17941 ttgtgttaat taagtcttta taaatatgag aaatacgcac atcatttaaa tactataggt
    18001 aaatttgtac atagactgtt taaatttttt tatagttatt gtcattaaca gtgaccttaa
    18061 taatatagca atttttaaaa tcaggaatgt atttacttaa aaaagataag gggactttta
    18121 atagtagtgg tattttcata agtacatcta tttttgaatt tagagttgaa aatgggtcag
    18181 gttcagcaat actacaaata ataaaaatat ctttttatga gtttgacaaa aaatataata
    18241 ctatacttaa tgaattaaat gttaaataat aaaaatattt agcggacaat tgatttcgat
    18301 tttatgaaga tgatatttag caattagaaa taatatataa tacaaattaa gtagtaatgt
    18361 tttagctgtt taaggacatg gtgctacaag aaaagtatca cctttttttt gttatacaaa
    18421 aaaacagttg actttttata tgaacccctt ctataatgtt actgaaatta agtaaaatga
    18481 ttgaacaaat gtaaagataa ttgaaaagct tgattttgga ggaaagcaaa tgaaaaaaat
    18541 tggagactta agattaatga tgaagtgttg ttcactttat tacgaagata atttgaatca
    18601 acaggaaata gcaaatcaat tgggaatatc aagaccaaca atatcaagaa tattaaaaga
    18661 agcttttgaa caaggaatag taaaaataca gatagttgat gttttgaaaa atgattacca
    18721 aaaaatagag agaagtttgg agagaaaata taaattaaaa gaagtaatag tagtagatga
    18781 taaacaggat gcactaacac aaaaacaaga actagcaaga gctgtatctg aatatttaac
    18841 tagagtagta aaggaaaatg atataatagg tgtttcaata ggaacaacac taaaagaaat
    18901 accaagatat gtggaaaaaa gtaattgtaa aaatgttaca tttatacctc tattaggagg
    18961 gattggagac aatgaaatag atattcatgc aaatcaaata gccgtaagtt tagcgagggc
    19021 ttttggaggt gattttaaat tattacatgc tccagctgtt atgtctgact tgtctacaaa
    19081 agagaaactt tgcaaagacg aaaaaattaa agaagtacta gatttaatag ataaaacaac
    19141 tatagcaatt gtgggtatag gaaatcctat gagtttaaac tcaacaataa tggcttctgg
    19201 atacatgaat gaagcagata tagaagattt aaaaaaatac aactcaatag gtgcaatttg
    19261 tttacaagcc tttgataaag aaggaaaaac ttctatactt gaatttaatc aaagagtatt
    19321 aggagtgaaa ctggaagatt taaaaaagat aaaaagaaca ataggtgtcg cttcaggaga
    19381 tgaaaaaata gaggcaataa aggcatcatt aaaagcgaaa tttataaata gtttagcaat
    19441 taatcacagt ttagcactta aattattaga agattgtgac taatagaaag atagataaaa
    19501 gttaacagga gggaatgtat atgtcaatat caaaagaaac attgcttgaa atgtataaga
    19561 gaatgaatca ggctagaaaa tttgaagaga aagttagttg gttttttgca agaggtatgg
    19621 ttcatggaac aactcactta tctgtaggtc aagaagcgtc aagtgtggcg gctgtaatgg
    19681 ctttagaaaa aggagattta gtatcattaa ctcatagagg acatagtcaa tttataggaa
    19741 tgggaataga cctaaataaa atgatggctg aacttatggg taaagaaact ggattttgta
    19801 agggaaaagg aggctcaatg catatagcag atattgagtc aggtaactta ggagcaaatg
    19861 gagttgtagg tggaggtctt acaatagctc caggagctgc acttacacaa cagtataaaa
    19921 aaacaggcaa aatagtttta tgtagttttg gtgatggagc atcaaatgaa ggtacttttc
    19981 atgaaggaat aaatttatct tcaatatgga aattgccaat aatattttac tgtgagaata
    20041 atttatacgg tatgtcaaca agcataaaac gtcatatgaa tatagaaagt attgccacta
    20101 gagcagcttc ttatggaata gaaggaatat caatagatgg atataaccca atagaagtat
    20161 acgaaacagt acaaaaagct gctgagaagt gtagaagagg agaaggacct gtattaattg
    20221 aaagtagaac ttatagatgg ttaggtcatt caaaatcaga tgcaaatgta tatagaacaa
    20281 aagaagaaat agaatcatgg aaagcaaaag accctattga atttttaaaa aattatctta
    20341 tagaaaataa tctatctaat gaagatgaat tagataagat tcaagaattt gcaaagcaat
    20401 caatagaaga tgcagtagag tttgctcaaa atagcccaaa tccaaaaata gagtctttat
    20461 tagaggatgt atatgcagac taagaatggt aaaggaggaa aataaaaatg agtacaaggg
    20521 aattaacata tgcacaagca ataaaggaag caatgtcaga agaaatgaga agagatgaaa
    20581 atgtaatatt tatgggagaa gatataggaa tatatggagg agcatttggt gtatcagttg
    20641 gtatgataga tgaatttgga ccagaaagag taagggatac tcctatatca gaagcagcta
    20701 tagcaggagc ggcagcaggt gcagcagcaa ctggcttaag acctattatg gaagtaatgt
    20761 ttatggactt tgtaacaatt tctatggatg caattgtaaa tcaagcggca aaaatgagat
    20821 atatgtttgg aggaaaagca caagttccaa tggttgttag atgcccagga ggttctggaa
    20881 ctggttcagc agagcaacat tcacaaagtt tagaagcttg gttttgtcat gtaccaggag
    20941 taaaagtagt tgcaccttct acaccagcag atgctaaggg attgttgaaa gcagctataa
    21001 gagataataa tccagtcata tttgttgaga ataaattgtt atacagaaaa aaaggttttg
    21061 tgccagaaga tgattatgta attgaaattg gaaaggcaga tattaaaaga gagggtactg
    21121 atgttacagt aattacttat ggaagaatgt tacaaagtgt tgaagaagca gcagagactc
    21181 tatcaaaaga aaatataaat gttgaaatta tagatttaag aactttatat ccattagata
    21241 aagagactat agtaaagagt gtatgtaaaa ctgggagagt tttaatttgc catgaagcag
    21301 ctaagactgg tgggctaggt ggagaaatat cagccctgat aacagaaagt gaatcatttg
    21361 attatttaga tgctccagta aaaagaattt gtggaaaaga tgtgccaata ccatataatc
    21421 cagagttaga aaaagcagtt gtcccaagag ttgatgaaat agaagaagca ataaaatctt
    21481 taattgttag ataaggaggg atagatatgg tggcaaataa aataaaagcc acaccagcag
    21541 ctagaagtca ggcaagaaaa gacaatataa aattagatag gctgattgga agtggagaaa
    21601 atggaaggat tcatttagta gatgtgttaa attatttaaa agataataaa gcaaatacta
    21661 ctcctttagc tagaagaata gcagaagatt taaatataga tttagaaact attgtaggta
    21721 ctggatataa tggaaagata agaaagtgtg atgtggaaaa attaactgca aaagaaacta
    21781 ttgtatcaac taatacatct aaatctagtg agaaaaaaga gctgaaaatt gaaaatgaaa
    21841 attcaagcat gtttaacaca gtagaaggaa tatttgaaaa gccaaatcca atgagagcta
    21901 ctgtagcaaa acgaatgtca gaaagttatt ttagtgctcc tgtatttaca ttcaatatag
    21961 aagtagatgc tacagaattg aaggtactta gagcaaagtt aatcgacaca gtaaaagaat
    22021 caactggagt aaaattaact atgacagatt taatagtaat ggcagtatct aaaatacttc
    22081 caaatcatca agccttaaat tcagcatgga cagatgaggg tatatttaga tataaagatg
    22141 taaatatagc tattgcagtt ggtttagatg aaggcttata tgttccggta gtaaaaaatg
    22201 caaacaaaaa gtctttaaaa gaaatagcaa aagaaagcaa agaacttgcg gaaaaagtaa
    22261 agacagggaa acttatgcca gcagaccaag aaggtaatac atttacaata agtaatgttg
    22321 gaatgtatgg tataactaca tttacaccta taataaatat gccttcaagt gcaatcttag
    22381 gggtaggtgc tacacaagat aagtttgttc cagtaaatgg agaggctaaa ataaaaccta
    22441 taatgaactt atcattaaca tcagaccata gagtaataga tggaacagta gctgcaaaat
    22501 tcttaaaaga tttaaaagaa ttgttagaaa atcctttatc aatgcttgta taggttttga
    22561 tattttgtta ctgatataaa tagtttgaat agattatatt attataattg tttcagtaaa
    22621 tttaaagctt ttatatatta agaattattt ttaacagtaa ctatatgtga atatgatttg
    22681 cttaattaaa atataagaaa ataaatagga ggagagccta tgtcagtaga agtaataatg
    22741 ccaaaagcag gagtagccat ggaagaaggt actatagtat cttggctaaa gcaagaaggc
    22801 gaagaagtaa agattggaga acctatacta gaaataacaa cagataaagt taatatggag
    22861 atagagtcag aaggagaagg tacacttgct gtaatcatac ataaagagga aggtgaagta
    22921 ttaccagtat ttacagtaat aggtgtaata gcagaaaaag gggaaaatca agaggaagta
    22981 aaagctaaat atttatctgg aaatgtttca aaagaagata cagttaaaga gaatcaaaat
    23041 atagaagtta aagaagaaaa aataaacaaa aaagagtgta atcatgatta tgatgtagtg
    23101 gtaataggag gaggacctgg gggatattta tcagcattaa aagcagctct tttaggtgga
    23161 agagttgctt tagttgaaga aaatatacta ggaggtactt gcttaaatag aggttgtatc
    23221 cctacaaaga cttatataaa aacagcagaa atattagaag aaattgacca attatcaaag
    23281 agaggtgtaa aagtaactgt agataaagaa caggacatta agaaggccat aaaatataaa
    23341 aatagagtag ttaaaaaact tacagctggt gttggcggat tattaaaaag tagagatgta
    23401 gatgtgttta atcttaaagc tagtgttaaa gaagagcata aagtaatttt atcagatgga
    23461 aaagttttag atacagaaaa tataataatt gctacaggtt ccaaagtaag gatattacct
    23521 ataaaaggaa tagaatcaaa tttaataata actagtacag aagcattaga tttggaaaca
    23581 gtgccagaag aattagtaat aattggtggt ggagtgattg gttgtgaatt tgcagagata
    23641 ttcaattcaa gaggttctaa agtaactata gtagaaatgg aagatagagt aatcccaaga
    23701 atggataaag agttaagcga atctttaaaa tattctctta gtaaaaaagg tataaatgta
    23761 ttaactaaaa agaaagtttc tgaatttaaa gaagaaggaa ataacatatt agtgtgcatt
    23821 gaaggtgaag agccaataaa agcagattta tgtctatatg ctataggaag agaagctaat
    23881 ctttctggca tagaggactt agatattaaa atagataaag gttcaatagt tgtaaatagt
    23941 aaaatggaaa caagtatacc aagcatatat gcagtaggtg atgttactgg aggtgtaatg
    24001 ttagctcatg ctgcttttaa aatgggagag gtagcagctt caaatgctct aggtgtgaat
    24061 aaagaagttg acttaggtgc attacctagt tgtgtttata caattccaga agtagcatca
    24121 gttggtatta cagaagagga tgctagaaaa aaatataatg taaaagttgg taagtttaat
    24181 tttgctggaa atggaagagc tttagcttct ggtcaagaac aaggatatgt gaaggtagta
    24241 gcagatgcta aatatggaga aattttaggt atacatatgt ttggatgtgg tgtagcagaa
    24301 cttataaatc atgcagcatc atttaaagcg ttagagatac ctactgatga agcaagtgag
    24361 ttgatatttg gtcatccatg tacttcagaa gctttaatgg aagctttggc agatgtaaat
    24421 ggagaatgtt tacacttacc taaaaaataa atctaaacat aaattattaa tttaagtcta
    24481 ttattaatat taatttatat cataaaattt taaaacactt acttagccat accccttatt
    24541 atgcaaataa tttatttgca taataagggg tattttttat ggaaaaatat agaatataga
    24601 atccttgtag tttttgttgt acaaaaaaga tagtaatata aaataacatt atcattttag
    24661 aatgatttca attgtaatta ggaaaagtga tttttttgtt tttagaaaaa gtattatttg
    24721 taaaatataa aaaaaaattt cttaatattt gaataaaaga atagcttaat ttaaatgtta
    24781 ttactttata aaaaaataat aagtacaaaa aaaacaatat atggcatata agttgctata
    24841 taaataataa ggagggaaca attataaatg aggcaaagaa taaaaaactt aattgaaaat
    24901 gaagataaga aaaatccttt aacagatgaa gcgatttcaa gtaggttaaa tattcgaaga
    24961 gaagatgtta cctttttgag aaatgagtta aaaatagaag attcaagaca aagaagaaaa
    25021 gttgttttaa ttaaagctat aaaagatatt ttaaaagaag aaaaaactat aaataaaaat
    25081 gatataacaa gaagattaaa cagcattggg tttacagtat caagatttac agtcatacaa
    25141 tacttaaaag agattcaaga ttctggtgac ctaaaacttg ataaagagag tgatgataaa
    25201 aaagaaaaaa taatcaataa tagagaaaat aaagatatag catttgataa acttataggt
    25261 agtagtggta gcttaagtac aattataaaa ctagccaaag cagcaattct ttatccacct
    25321 catggtcttc atactattat tatggggcca actggtgttg gaaagagtga gttagcagag
    25381 tgtatgtata aatttgcagt agaatcatcc agattcccta agaatgcacc atttatagtt
    25441 tttaatgcag cagattattc agagaatcca cagcttttgc tatcacagtt atttggacac
    25501 gttaaaggtg cttttacagg agctgatgag aacaaagaag gattagtatc aaaggcagat
    25561 ggaggaatat tgtttataga tgaaatacat agattacctc atgaaggtca agaaatacta
    25621 tttcaactga ttgataaagg tatggtcaga aagttaggag aaacaagact aacacataaa
    25681 atagatgtaa tgattatttc agcaacttct gagccaatag attctcattt acttaataca
    25741 tttaaaagac gtatacctgt aacaattgaa ataccagaat tagttgcaag accattaaat
    25801 gagaggtttg acattataaa taatttcttc ttaatagaag ctcaaagaat gggagcaaac
    25861 atacatataa agtcagatgt attaaaagct cttatgcttt acgattgtat aggtaatgta
    25921 ggtcaactta gaagtgatat tcaagtagct tgtgctaggg gactattaaa ccaacttaca
    25981 aacaaactaa aagaagtaaa tataagcata tcagatgtac ctggatatgt aaaacaaggt
    26041 cttataaaaa tcagaaattg tagaggcaaa atagaaaatt atgtagatgg ggatttaatt
    26101 atagattcaa atcttcaagg tgagatagaa aagaaaaatg aagatatata tacttttcca
    26161 gatgaaatat acaaacttac tgaaagaaga catattgatt tattggaaca aggtttagat
    26221 tttgatgtta taaatagaat cattggagga gaattagaaa gttgcattca aaaatacata
    26281 aaacaagtta aaaaagtttc tattagtaac aatcttccag atataagtcc aattgttgga
    26341 aaatatatcg tagagctaac ttatgaagta attaaaatag catcacaata cctcagttca
    26401 ctagaaccga atctacattt atgtttagca gttcacctaa aagcagcttt tgagagatta
    26461 aaagaaggaa aagtaatatc aaatgctcat ttgaaagaaa taataggaaa ttatccagta
    26521 gaatattctg tagcagaaaa ggtagctcaa tatttaaagg aaagatataa cataaactta
    26581 ccaaaagaag aaataggtat aatagcaata tattttaaaa tgagtagtag aagagatatg
    26641 tctgaacaaa aaaagatagg tgtacttctt atggctcacg gaagagtagc atcttctgta
    26701 tgtgaggtta caaataaact attaggaatt aatcacgcaa ggtatttaga tatgccattt
    26761 gagaagaagc cggaagaaat gattgaagaa gctactacaa taataaaaga tattgatgaa
    26821 ggtagaggtg tgattatatt agtagatatg ggttcacttt catattttgg agatattatt
    26881 tctggaaaga ctggaattaa tataaggaca atatctagat ttgatacatt gctttctata
    26941 gaggttatac gaagagcagt tttaccagat ttaacaatag acgagatagt tgatgaagtt
    27001 aaaggtatag agccacaagt aaaagaaaag gttagtaaat gtaacaatac aaaagtagat
    27061 tttagaaaac ctataatttt aacattatgt attactggat tagggggagc ttgtaagata
    27121 aaaaaaatct tagaggaaaa tattaaaagt ataactgaaa aggttgatat agaacctata
    27181 ggtatgattg aatatccaag tcttgattta gagataaaac aaataagcaa tgataaaaat
    27241 gtaatcgcca tagttggaac aattgaccct cagatagcaa atatcccttt ttttagtcta
    27301 gtagacataa atgataaagc aaagttaaat caaataaata acctaattga tacaaatcaa
    27361 attggtgaaa caaataaaaa atatgaatta tcagatttaa tacataaaga agatatattt
    27421 gtggatttac aggttaaatc aaaagaagaa gttctaaaat atatgagtaa aaaacttaga
    27481 gagaaaggtt atgtgacaaa aaatttctat aaaaaagtag tggaaagaga taacttattt
    27541 ccaactgaat tatcagatga aatagcaata cctcacacag atggaataga tgtaattagg
    27601 ccagctataa gtatagccat cttaaagaag cctattgtgt ggagtaaaag taaagtaaaa
    27661 ataatacttt tattagctgt agaccaaaag tgttttaatc cattaagcac tctactctca
    27721 tttatagaaa cagatgaatt taagaagata aaaaacatta aagatagaga ttttattagg
    27781 gagatgatat tagatggagt caatgaaaat aattagtagc aatttaattt ttaaaaatat
    27841 tgaagtgtct aacaatgaag atgcattaaa gtttttggga caacgtttgt ttgacgaaca
    27901 gtatgtaaaa gaaagctaca tacaagctgt tgtagcaaga gaaaaaaagt atgctacagg
    27961 gttaccaaca gaaatatacg gagtggcaat accacataca gatatagtac atgtaaatga
    28021 gccaggaata gcaattggaa tactgaataa acctgtaaaa tttataatga tgggtacaga
    28081 cgatactgaa attgatgtaa aagttgtatt tatgttagca gtgaaagagc cacaagaaca
    28141 attgcaacta ttagaaaaac ttatgactat atttcaagat aagaatatac taaataatat
    28201 tgttgactta agtgaagaaa gtgtgagtga tttattaaac tctaaattga aaaattaaac
    28261 atgtaaagta tattaaaaat gtaaaattaa acatgcaaag tatgttaaaa aatataaaaa
    28321 gattattaaa gatttctaac tatagatatc tttaaaataa aataatttca atgggggtga
    28381 ctaatgtggc taaaaagata ttagttgcat gtggaacagg agtatgtact tcaacaattg
    28441 ctataaacaa attaaagaaa gcacttcaag acattggtaa attggatatg gttaatatta
    28501 cacaatgtaa agtagtagaa gttgcatcaa aagcacctga ttatgattta ataatttgta
    28561 ctacacaagt atctagtagt ataaaaacac cagtgataaa tggcttacct tttttaactg
    28621 gtgtcggaat ggataaatta atcaatgatg tattagaaga gttagaatta taattaaaaa
    28681 aattaaggaa catggtctct aaaatcataa gttttagaga cttaaaatta aataatggag
    28741 ggtctttata tggagatatt aaatttcatt gttggtctag gtgcacaagt aatgatgcca
    28801 ataataatat gtatttttgg tttgatatta ggtacaaaac taggaaaatc tttaagagct
    28861 ggtttaactg tgggagttgg gtttataggt cttaacacta ttatagcttt gctaacagat
    28921 aatttaggtc cagctacaca acaaatggtt aagaatttag ggctaagttt atcaataata
    28981 gatgtaggat ggccagcagc atcagctata gcttttgcat caacagtagg ggctttaatt
    29041 attccaatag gtcttgtggt aaatatagtt atgctaatta ctaatactac tcaaactgtt
    29101 gatgtagaca tatgggatta ctggcatttt gcttttacag gagctttagt ggcaggggct
    29161 actcaaagtg taatgtgggg agtatttgca gcagtagcaa atatggtaat tgtattggta
    29221 atggcagatt taactgctcc aggtatagag gaatatttag gtatgccagg tatatctctt
    29281 cctcatggat ttacacaggc atttgttcca attgctatag tagtaaataa attattagac
    29341 ctaataccag gcataaataa gattgagata aatgctgata cattgcagaa aaaatttgga
    29401 ttatttggag aacctttaat aatggggtct gtaataggtg taataattgg tattgctgcg
    29461 aaatatgata taaaaggaat attacaatta ggtgtaacta tgggagctgt attaatatta
    29521 attccaaaga tggcagcatt attaatggaa ggattattac cagtatcaga agctgcacag
    29581 gaatttattg agaagagatt taaaaacaga ggcaagattt atataggctt agattcagca
    29641 gtaggaatag gtcatcctgt tacattatca gttgcactag tgttggttcc tttgactata
    29701 cttatagcag ctatattgcc aggaaataaa gttttaccat ttgcagattt agcagtaatt
    29761 ccatttgcac ttgtattaat cgtaccaatt acaaagggaa atgtgtttag aacattaata
    29821 ataggaataa ttataattac ttctggatta ttaatcgcaa ctaacttagc tccattattt
    29881 acccaaatgg ctttaaatgc tagttttaaa atgcctgaag gagcaactat gatttcaagt
    29941 atttgtgatg gtgcgaatcc attaagttgg gtatttgtaa aagttatgaa ctataaagtt
    30001 attggaggag tagtttttgg agttatagct ttaggaatgg ctatttacaa taggaataga
    30061 ataataaatg aaaataaaaa gctatctata gaagaataag gttaaaacaa ttttattaag
    30121 gagtgtatag gttatgaaaa aatataaata tgattctaaa agatacttac tcagtgttac
    30181 aataccagga ttttttatga ttttaatatt gatttatgca ctgtttaata actatacaaa
    30241 ttttaatttg aatatatata gtttgttaat aattgtctgt acttatggta tattcaatac
    30301 ttttatatca tcaagtaatc ctaaaaaaat tattattgat agcaaatgta tacattttac
    30361 ctcatttatg actacacata agtatgaaat taaagatata gaaaagataa gaataagaga
    30421 attttataat aaaaaaattt atctaaaaat taatgatgga aaccttttta aaggtaggta
    30481 ttggataaga acaaatatgt ttaataatag tatagcatta tatagctatt tcattgagtt
    30541 ggaagagtgc ttatatccag attcactaaa atttagaaat aaaaaatttg agaataagaa
    30601 catataaaaa taaaaaattg aattgaagcc tagcttaatc ttttttgata agatataagt
    30661 ttgaacttta tactaaattt ttagaatttt caatcaagac aataacataa tagctaagca
    30721 attagaacac aattaagatg tataaggcat gtatatgatg aatgggagga tttaattaat
    30781 gttattagag aaattaagaa aagaagtatt acaagcatct ttagaccttt taaactataa
    30841 tttagtgaca ttaacaggag gaaatgtaag tgggagagat gaacaaactg gctatatagc
    30901 aatcacccca agtggaatgg attatagaaa tcttacacca agtgatattg ttatagtaga
    30961 tgtagatgga aatattatag atggaaaatg gaaagcatca gtggatttat cagaccactt
    31021 gtatatatat aagcatagag aagacataaa tagtataatt catacacatt ctacatactc
    31081 aagttgtttt gctattttaa atgaacctat agaatgtgca agtacaactc ttgcaaatga
    31141 agtagggggt tcagtaccag ttgcaaaatt ttcgccacca acatctaaaa agatgggaaa
    31201 atgtgttatt gaagcaattg gtgacaaaag agcatgtctt ttagcaaatc atggcgtaat
    31261 tgcagttggt ccatctgtag gacatgctct tacagccgct gtaatgttag aagattcagc
    31321 aaaagtatat tacttagcaa aatcaattgg cacaccagtg ctactgcctg atgaagaaat
    31381 tcaaagagcg agagatgtat tttttaatgt ctatggtcag gataaataaa ttagataaaa
    31441 ttttaaaagt aatatgaaaa tatagatatt caatgatatt aaggagattt ataatgatat
    31501 aataagttta atagttaaga agtaaaatat gaaatgtaat agtatataaa ttcatttaag
    31561 actaaaaata ataagataaa ataaaaagga gtctgtattt ctatgtatta cttattaaac
    31621 aaaagcacaa atccttactt taatttggca ttagaagaat atctattttt aaatgataaa
    31681 tataatgatg atattataat catatggaga aatgaagaat ccatttttat aggtaaaaat
    31741 caaaatccat atcaggaagt atatcatgat gttattgaaa agggagaaat tcctatttta
    31801 agaagaatat ctggaggagg aactgtttat catgacttag gtaatatcaa tatgtcattc
    31861 atacaaaaag ataggcaact tcatgagata gattttttgg agcatactaa gtttatgcaa
    31921 aagatgcttt caaccttagg actagatgta tctataactg aaagaaaaga tttattttta
    31981 aatgggaaaa aaatttcagg ttctgcacag tctataaaaa gaaaaaattc tctttatcat
    32041 ggaactcttc tttacgattc agatttaaat aaattaacta aatatttaaa ttcaaataaa
    32101 gcaactgaat caaatgcaac taaatctgtt tcaagtaaag ttacaaatat taagttttta
    32161 ctcgaaaaag atataaatta ctttttagat tattgtgttg aatatttaaa atctaatata
    32221 aagaatataa aagaacttga attggatgaa gaagatatta aaagtgtata caatatagga
    32281 gaagataaat ataaaaagat agagtggaca tatggtaaaa cgccgaaatt tcaagtagtg
    32341 ctaccattta ataatgaaag taaaataaat atacatgtta acagatggaa agtatcaaaa
    32401 ttttttattt cttatgatga taatgtaatt aatatggaca agctgttaga tttgaatttc
    32461 tttaaagaag aaataaaaga gagtatttta gaaaattatc cacattacat agatttaatc
    32521 aatttaatat tttaatataa aacctctaat ttgataaaat tgtcttatat caaactagag
    32581 gtttttaata ttcttgcata ttaacaacca ttacaaaatt gtaaaattaa aaacaacact
    32641 attgaaaaat caatatatat tgtaataaat atatgtgttt tttattagca aatagacatt
    32701 aactatttat acaactgaaa atttaatata taattaatca gatggttaaa ataaaaatat
    32761 taaaagtttt aataaatgat ggttaaaaat aaaatacgag gtgataccat gtatagtgtt
    32821 ataattgttg cagcgggaag cggaaggaga atgaacttag atataaacaa acagttcata
    32881 aaattaagag aaaaagaaat tattgctcat acaattcaag ttttttatga aaatataaat
    32941 atagatgaaa tagtggtatg tataaaaaaa gaagaagaag atttttttaa agaaaatata
    33001 ataaataagt ataactttaa aaatataaaa atagcatatg gcggaaaaga aagacaggac
    33061 tcaatatata atggtttaaa aaaattagat aaaaattgtg atatagtact tatccatgat
    33121 ggagcaagac catttgtcga ccatagaata atcaatgaat ctataaaggt agctaaagaa
    33181 aaaaaggctg tggttgtagg tgttccagta agtgatacta taaagatagt gtcagatgga
    33241 acagtacaag aaactccaga aagaaatttg ctgtgggcag cacaaacccc tcaaaccttt
    33301 gaatataatc tcataataga tgcttatgaa caagcatata agaacaatta ttatggtact
    33361 gatgattcaa tgttggtaga aaatataggt caaagtgtca ctatggtaat gggttcttat
    33421 gaaaacataa aaataactag tccagaagat ttaaatatag cagaacaaat attaaatatg
    33481 gaaaaaagag atgaagttaa cagtagaagg agaattatat gagaatagga ttaggatatg
    33541 atgtacacaa attaacagag gatagaaaac ttataatcgg tggtgtagag ataccacacg
    33601 ataaaggttt gttgggtcat tctgatgctg atgtattgat acatgcaata atggattcta
    33661 ttttaggtgc tctagcatta ggagatatag ggaagcattt cccagataca gatgaagaat
    33721 ataagggagc agatagtatg aaattattag aacatgtgta taatctaata acaagtaaag
    33781 gatataaaat tggtaatata gatagtacta taattgctca aagccctaag atggctccat
    33841 atattgagag tatgagaagt aatatatcaa aagttttaaa cacagacatt gataatataa
    33901 acataaaggc aacaacagaa gaaggtcttg gttttacagg agcaaaacag ggaatagctt
    33961 cacaaagtat ttgtttatta ttgttgacaa gtcagaataa ttaatatatt attagtaata
    34021 agtttaatgg atatcaagta ataggcctat atagaatatc tataatgtat gaatttaagt
    34081 gaaattaata taaatataaa attagctatg ataaagaaat agtaaaatga tgaaatcttc
    34141 acagagagaa aacggtggtg agagttttca agaggaagtc tttgaacctg tcttttagct
    34201 taaaggtata aaaatcttta cggtaggaac cgttatattc ccaaaagaga gctattcata
    34261 tagctaacta gagtggtacc gcggaaatta aacctttcgt ctctatactt gtatagagat
    34321 gagaggtttt ttatattttc aggaagttaa tattcaggag gaatctatta atgaaaatgt
    34381 caaaaatgtt tatgccgaca ttaaaagaaa tcccagcaga tgctgagatt acaagccatc
    34441 aattaatggt taggtcaggc atgataaaaa aaatgacttc aggtgtttat aaccaattac
    34501 caatggggtt aagagtgttc aaaaaaattg aacaaataat tagagaagaa ttaaataaaa
    34561 aagattgtca agaaatactt tgtgcagcct tacttccttc tgaattatgg aaagagtctg
    34621 gaaggtggac tgctatgggt gaagaaatgt ttagactaaa agacagaaca gaaagagagt
    34681 actgtcttgg gccaacacat gaagaagcat tcactgatat aataagacaa gaaattactt
    34741 catataaaca attgccactg aacttgtacc aaatacaagt aaaatataga gacgagagaa
    34801 gaccaagatt tggtgttatg agaactaaga cttttacaat gaaggatgcc tatagttttg
    34861 atgtagatga taaaggttta gataagtcat atcaagatat gtttgatgca tatgtaagta
    34921 tatttgatag atgtggattg gagaatagcc ctgtacaggc agattcagga gctataggag
    34981 gttctacatc agccgaattt atggttaagt cagaagttgg tgaagatgaa gttgtatttt
    35041 gtagtggatg tgattatgca gccaatgtag aaagagcaga atcttgtaat ctagcatcac
    35101 aaaaagaaga aatgaaagaa ttagaagagg ttcatacacc aggagcagct acaataaaag
    35161 agttagaaga atttttaaaa acttctccag ataagtttgc taaaacttta gtatatgagg
    35221 cagatggaaa aacagttgta gtcgttgtaa gaggagatag agaagttaat gaaatcaaag
    35281 tatctaatgc cataggttct gttatagaat ttgctcttgc tacagatgat gtagtgagaa
    35341 aagtaactaa tgcagaagta ggatttgcag gtccaatagg tataaatgct gactatgtat
    35401 ttatagataa agaaattgtt gaacaaagaa acatagttgt tggggctaat aaaactgagt
    35461 accatataaa aaatgctaac tatggaagag attttgaagg aatagttgga gactttagaa
    35521 atgttcaaga aggcgacaag tgtatagtat gtggtaagcc acttgaaata gctagaggtg
    35581 ttgaagtagg acatatattt aaactaggaa ctaagtactc agaatctatg aatgcaaact
    35641 tcatagacaa agatggaaaa tcaaagccta tagtaatggg atgttatgga ataggtgttg
    35701 aaagaacagc agcagctata attgaacaac ataatgatga gaaaggtata atatggcctt
    35761 tgtcagtagc tccataccat gttgtgatag ttccagcaaa tatgaaaaat gaagaacaaa
    35821 tatcaatagc tgaaaatata tataatgatt tgcaagctat gggtgtagaa gttttattag
    35881 atgacagaga tgaaagaata ggtgtcaaat tcaatgattc agaattaata ggaataccta
    35941 tgaggattac agtaggtaaa aatattaatg aaggtaaagt agaatttaaa cttagacata
    36001 aagaagataa agagataatt gacatagaag aaataaatga aaaagtaaag gcagagttta
    36061 tcaggaataa tgttaggtta ggataataac ttaaataaga tattgtatag ataatcaaag
    36121 ttgtacttta tagacaccat tttatctata tataaggata taaaatggtg tttttttata
    36181 aaacaaataa atgaggaggt aattaaaatg gcaaaaaatg aaaaacaatt tgttgaagaa
    36241 ataacaaaga tggaagatga ttttccacaa tggtacacag atgtaataac taagactgac
    36301 ttagttgatt atgcaccagt aaaaggtttt atggttgtaa agccatatgg atatgcatta
    36361 tgggaaaaga tgcaagaatt tatggataaa aaatttaaag aaactggaca taaaaactgt
    36421 tattttccat tattaatacc agagagttta ttaaacaaag aagcagaaca cgttgaaggt
    36481 tttgctccag aagttgcatg ggtaacacat ggaggaaata aaaaattaga agaaagatta
    36541 tgtgtaagac ctacttcaga gactataata tgtacaatgt atgcgaaatg gttaaaatca
    36601 tatagagaat taccatatct ttataatcaa tggtgctcag ttgttagatg ggaaaaatca
    36661 actagacctt tcttaagaac atctgagttt ttatggcaag aaggtcatac attacatgaa
    36721 acagcagaag aagcacaaga agaaacaata caacaattag aagtatataa agcgctatgt
    36781 gaagaattac ttgcaatgcc agttgtagct ggtcaaaaaa gtgaaagtga gaaatttgca
    36841 ggtggtgaaa gaacatatac tatagaagct atgatgcatg atggtaaagc attacaatca
    36901 ggtacaagtc acttcctagg tcaacacttt actaaggctt ttgatattac ttttgcagat
    36961 agggaaggaa atttagctaa tccataccat acatcttggg gagcatctac aagacttata
    37021 ggtggactta taatgactca tagtgataac agaggtttag tattaccacc aagagtagct
    37081 ccaattcaag ttgttatagt tcctatagct gctaaaaaag gaaatgtaat ggagactgtt
    37141 gataaaatat atgctgattt aaaagctaag ggagtagctg tagaagttga tgatagagat
    37201 aactatacaa ctggatggaa atttaatgag tgggaaatga aaggtgttcc agtaagagtt
    37261 gaaattggac caaaagatat agaaaataat caagctatgg tatttagaag agatacttta
    37321 gaaaaggatt ctatgccttt agaaggatta gctgatgcta tatgtgattt atttgatgtt
    37381 atacacaatg atatgtttga aaaagcaaga aaacatagag aagacaatac atctatagtt
    37441 gaaaatatgg atgagtttag aaaagcttta gaagaaaagc caggattcat aaagactatg
    37501 tggtgtggag atgcagaatg tgaagctaag attaaggaag aaacaggagc aactataaga
    37561 tgcttacctt ttgaacaaga aaacttaggt cacaagtgtg tgtactgtgg aaaagaagca
    37621 gatagtatgg tagtaatggc aaaagcttac taaaatacat ttaaataaaa actggggtag
    37681 aaagtattta atactttatc ccagtttttt gttttttatg agtaataaaa tgtatttgta
    37741 actatgtcat aagataagtc atagatactt atattaaaaa gaatataata gagaactatt
    37801 tttaataatt acatattaat gaaagcaaaa tattttgtta tatagatttt caataaagca
    37861 aacaataaat ataaatgaat attaataagg agtgctttta atttttagaa aataaatgac
    37921 ttaaaagaaa gatttatgaa attaaaacta ggattttctg atataataaa catgtgtatt
    37981 tttaaataaa aaggatatta ttattagatt tgattaaaaa taaacttgca aaacaatgta
    38041 ctagtttaat attatagtta tattgaataa aatatcagga ggaagtaaaa atgaatgtaa
    38101 gagtaaggtt tgcaccaagt ccaacaggat ttgtacatat aggtagtttg agaactgctt
    38161 tatataacta tttatttgca aaaaaaatgg gcggagaata tatattaaga gtggaagata
    38221 cagaccaaag tagattagta gaaggtgcta tagagaatat gcttaatgct atgaaatggg
    38281 ctggggtcaa ccatagtgaa ggtgttatat tagatgatag tggaaaagta gtacaaaaag
    38341 gagaatatgg tccatatatt caatctcaaa gattagatat ataccaagaa tatataaagc
    38401 aacttttaga tagtggaaaa gcttattact gtttctgtac aaaagaaaga ctggatgaag
    38461 taagagatgc tcaaagagca gcaggagaaa cagctaaata tgatggtcat tgtaagaatc
    38521 tttctaaaga agaagtagaa gcgaatataa aagcaggaat accatatgtt ataagattaa
    38581 gattgccaga gaatcataca attaagttta cagacttagt tagaggagat atggaattta
    38641 atactaatga cttagatgac caagtattaa tgaaaacaga tggatttcca acttatcatt
    38701 ttgcagtagt tgttgatgac tatttgatga aaattacaca tgttataaga ggagaagaat
    38761 gggtatcatc tactccaaaa catgtttatt tatatgaagc ttttggatgg gaagcacctg
    38821 tatttgtgca tttaccaaat atacttaata aagaaaagaa aaaattaagt aaaagacaag
    38881 gtgatgtagc tgttgaagac tttaagaaaa aaggatattt accagaggga ttagtaaact
    38941 atgtagcatt agttggttgg tctcctgaag ataatcaaga attgtttaca atggaggaat
    39001 tagaaaaagc cttctctgta gaaagagtct ctaaaagtgg tggagtattt gatactgaaa
    39061 aattaaattg ggttaatcag cattatataa aagatggtga tgatgcttat ctaacagact
    39121 tagcaatacc atttttaata gaagatggat ttataacaga agaagaagct actaataaat
    39181 atgatttctt aaagagtatg atatcagtac ttaaagagaa attacaatat gtaaaagaag
    39241 ttactgaaca tgcaagtata ttttttggag ataaaataga ggtagaaact gaagagggaa
    39301 gagagttctt aagattagaa catataccta ctttaataga tgctttgaga gaaaaaatag
    39361 aaaaaacaga ggtattaaat gctgagtttg ttcaagctat gcttaaagaa atacaaaaag
    39421 agtacaaaat aaaagggaaa aatttattta tgggctcaag aataattttg acagggcaaa
    39481 tgcatggtcc agatttacca aaagtaatgg aagttttagg aaaagaaact tgcttaaata
    39541 gaatagctta tgtaaaaaat aatatattat agtcataaaa gtccgctaat ttagaagcgg
    39601 actttttttg tgttagtatt tggtgaaaat atctgcttaa gaaaatgaag gtatttaagg
    39661 taataaattt aatatataaa aagcaaagca aaaatataaa taaaatatga ataataaact
    39721 aataaaatat taagcataga agaagggaat ctattatttt agtttgattt aattattaag
    39781 ggggtaatta ctatgtatag taatattgat gatgttaaaa aggaattaaa ggagctatgc
    39841 ttagaatatg ttacaatttt agaaaaatta aaagatgaaa aaatgattac agaagaaact
    39901 tttgaaaagt gctcttctca aaaaaaaata tttttagaag aacaatagag gatggtaata
    39961 gtattattat tatgtagttt gaaagatagt acgaaaaatg atagtaatac tattatttat
    40021 tgcaattttc aactataata taatatataa tgttaagaag ataatttata aaaatacagt
    40081 gaggtgatga gtgtgaaagt ttataataca ttgactagaa caaaagaaga atttgttcca
    40141 ttagaagaag gaaaggtaaa aatgtatgtg tgtggtccaa cagtttataa ctatatacac
    40201 ataggtaatg caagaccatt tataatattt gatactctaa gaaggtattt agagtataga
    40261 ggatatgatg taacttatgt acaaaacttt acagatgttg atgataagat tataaataga
    40321 agtcatgagg agggaatatc tcctgaagaa gttgcggcta agtatataaa agaatatttt
    40381 gtagactgtg atgggctagg aataaaaaga gctactgttc atcctcaggt tacagataat
    40441 atacaacaga ttatagagtt tataaaagag ttggaagata agggatatgc atatgcagta
    40501 aatggtgatg tatattttga tacaaataag tttgaaggtt atggaaaact ttcaggtcaa
    40561 aaacaagaag atttagaggc aggggctaga attgaggtta atgaccaaaa aagacatcct
    40621 atggactttg ttctttggaa ggcaaaaaaa gaaggtgagc caggatggga tagcccttgg
    40681 ggagaaggta gaccaggatg gcatatagaa tgttctgtta tgtctaagag atatttaggt
    40741 gaaacaattg atatacatgc aggtgggcaa gatttaacat tcccacatca tgaaaatgaa
    40801 atagctcaaa gtgaagctag aagtggaaaa acattctcaa aatactggat gcataatgga
    40861 tatataaata taaatgatga aaagatgagt aaatcaaaag gtaatttctt tacagtaaga
    40921 gatatatcaa aattatatga tttagagata gtaagatttt tcatgttatc agcacattat
    40981 agaaatccag taaactttag tgatgagatg ttaaatcaag ctaaagcagg tcttgaaaga
    41041 ctatataata ctaaagaaaa attagaattt acgctaagta atttagtaga atctccgtta
    41101 acagaaaaag aagtagagct tgttaaagaa ttagatgact ttagacaaaa attcatagat
    41161 gctatggatg atgatgttaa tacagcagac gcagtaagtg taatatttga attagctaag
    41221 ttaataaatt ctaatgtaga tgaaaattct tctttggagt ttgctaaaaa atgcttagat
    41281 gaatttaatg aacttacagg agtattaaat attgtaaata agaaaaagga tactgtatta
    41341 gataaagaca ttgaagaatt gatacaaaaa agaactgatg caaagaaaaa taaagagttt
    41401 caattagctg atgatattag acaacaatta ctagatatgg gaattgtatt agaagacaca
    41461 agacaaggtg ttaagtggaa aaggatataa aaatggaaaa aactgaatta gttactatgt
    41521 caccattagt tttagcatac ttaggtgata cagtgtatga gacatatata agagaatatt
    41581 taattagaca gaatacacaa agaaaagtta atgatttgca taaactagct ataaagtatg
    41641 taaaagctaa agctcaggca actataattc atgaaattga aattgagtta actgaagaag
    41701 agagtaaaat ttataaaagg ggaagaaatc aaaagtcaaa tacttctcct aagaatgcag
    41761 atattataga ctacaaacat gcaactgggt ttgaggcatt agttggatat ttgtatttaa
    41821 ataatgaaat agagagactt caatatatta tcaataaagg aatcaaaatt attgaaagag
    41881 atatgtaaat attaaagagt gttgtcttaa taataagtaa taaggcaaca ctttttttat
    41941 aactaatgta taataaatat atagaaatta gtaatgagaa aggataaaaa gttatgaaag
    42001 taaaattaat atcacataca cctgaaccag aaaaagtaat agctatggca gctaagctat
    42061 gttattcacc agttgggaca gacgaaatag aaaaagactt aacagatgaa agtatagaga
    42121 aatttttaaa tatgttatta agtataggtc atgggtcaat attagaacat gcttcattta
    42181 cattttcaat agaaggtatt tcaagggcat gttcacatca aattgttaga catcgtatag
    42241 ctagtttttc acaacaaagt caaagatatg ttaaattaga acaatttgag tacataattc
    42301 ctccagaaat agaaaaaata gaaaaggcaa aagagttatt tatagactcc atgaaaaaag
    42361 accaagagaa ttatgataag ttagttgaaa tattgtttga aaatcattat aatgacctaa
    42421 taaaaaacgg taaaaatgag aaaacagcta aaagacaagc tgagaagaaa gcaatagaag
    42481 atgctagata cgtatttcca aatgcatgtg aaacaaaaat ggtatttact ataaatgcta
    42541 gaagtttgtt taatttcttt gaacatagat gctgtgaaag agcacagtgg gaaataagaa
    42601 atttagctgt ggagatgtta agagaggtta aaaaggttgc tcctatatta tttaaaaaga
    42661 ctggtccaag ttgtgtaaat ggaagttgtc cagaaggaac tatgacttgt ggagatatag
    42721 ttcaagttag agaaaaattt aaggccttgt aggaggtgaa taatttggcg agtatagaag
    42781 gaagaaatcc ggtaatagaa gcaataaaaa gcgacagaga aatagataaa atattaattg
    42841 caaattcagc taaagaaggt tcaattaaga aaataatagg aatggctaaa gataagaata
    42901 taattattca gtatgttgat aaacataagc tagatgaagt aagtacaagt cattcacatc
    42961 aaggtgtaat agcttatgca agtgagtata agtattatga attagatgag ctaatagatt
    43021 tagcaaagaa taaagatgaa gacccatttt tcattatatt agatgagata acagacccac
    43081 ataatttggg ttcaataata aggacagcag atgcagtagg agcacatgga gttatcattc
    43141 caaaaagaag gtctgtacac ataactcctg tagttgccaa agcatctgct ggagcagtag
    43201 aatatatgcc agtttgcaag gtaaccaata tagttaatac aataaaaaga ctcaaagaag
    43261 aagggctgtg gattgctgca gctgatatgg atggagaaac tttttataaa caaaatctta
    43321 ctggtcctct tggtgtagta attggaagtg aaggttttgg aatatctaga ttggttaaac
    43381 aaaactgtga ctttatagta aaaatgccaa tgataggtaa tgttacatct ttaaatgcat
    43441 ctgtagcagg tggaatactt ttatatgaga tattcagaca aagactggat aaaagtaaat
    43501 aggcatgaaa aaaaatataa atcattactt aataatagat ggctacaata ttataaatgc
    43561 gtgggacaat ttgaaagaac tggctaaaga ggacttagaa gattctcgag aaaagcttat
    43621 tgatgacatt atagaatttt ctgagtttat gggttataag actataatag tttttgatgc
    43681 ttataatgtt aaaaattctc gagaaaaagt tgaaaaaaga aaacacataa caatagttta
    43741 tacaagagaa caccaaacag cagatagtta tatagagaaa tttataactt ctttatcaaa
    43801 gtatgatgat gtaaaagtag ccactaatga ctatgcagaa cagcaaatga ttttaggaaa
    43861 aggtgctact agaatgtctg caagagaatt aaagttagag ttagatcgtt ccaagaataa
    43921 aatgaaggaa aaaaatatcg gtttgaggaa aaaaattcag cgaaattggt tggaggaaag
    43981 gttagataaa gaaacattgt cgaaacttga gaacattcgt agaaagcgtt gaaattacta
    44041 ggttctttag actataatat acctataaat ttgttttata tatgggggag atttacatgt
    44101 tggtagcaaa agaaaaaagt tatgagttag tggacaattg tcagcaggat gagtataaca
    44161 ttgtattaag agcaagtgaa ggggataaaa tagcactaga gtacattatt actaaataca
    44221 gaaattttgt aaaggcaaaa gcaaagtcat attttttaat tggagcagat aaagaagata
    44281 taatacaaga aggaatgata ggcctttata aggcagttag agattttgat ggaagtaaga
    44341 ccaattcatt taaatgtttt gcggagatat gtataacaag acaaataata actgctataa
    44401 aaactgcaac aagacaaaaa catatacctt taaattcata tgtttctttg aataaaccaa
    44461 tatatgatga agagtcagac agaacacttt tagatattat agctacaagt atagtaacag
    44521 atccagaaga gcttataatt agtaaagaag agttaaaaaa tatagaatca aaaatgaacg
    44581 aattgttaag tgacttggaa ttagaagtac tagaattata tttaaatgga aagtcatacc
    44641 agtttatagc ggacaagctt aaaagagatg taaagtcaat agataacgct ttacaaaggg
    44701 ttaagagaaa attagaaaaa catcttgaaa acagaaatga ttaatagtaa aatacttacc
    44761 ataagcttat tgtgagcaaa attaatttat atcgaaagat aagggaggaa attcaaaatg
    44821 gctaaagcta aatacgaaag aacaaaacct catgttaata tagggacaat aggacacgta
    44881 gaccacggta aaactacatt aacagcagca ataacaaaaa cattatatga cagatatcaa
    44941 ttaggagaag cagtagattt cgcaaacata gataaagctc cagaagaaag agaaagagga
    45001 atcacaatat caacagcaca cgttgagtat gaaacaccaa atagac
//
LOCUS       DAEORM030000030        42078 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.030, whole genome shotgun sequence.
ACCESSION   DAEORM030000030 DAEORM030000000
VERSION     DAEORM030000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 42078)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42078)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 42078)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42078
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.030"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            24..692
                     /locus_tag="KRH23_002150"
     CDS             24..692
                     /locus_tag="KRH23_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YwaF family protein"
                     /protein_id="HHS5225428.1"
                     /translation="MFKIFLFSSEQFVSLFIFGLFLYYCPKLTKNILPYSYTVEKIIC
                     TLLVIIMALEQLLLISSGNYSTLNSLPIGINYICIYLCIAILIFKQYHLFNIFFSWSL
                     VCSVGELIFSKNLGYEFPSLIYFIFIFSKCLIIYADIYMVDVRKFRVNRYALRDNLAI
                     CFIYFSFIFLLNTFTNSRYYYGFLSHSTTAIFTFIFVTSIMYIPALLFNRDTFILEKK
                     KKSK"
     gene            complement(783..2234)
                     /locus_tag="KRH23_002151"
     CDS             complement(783..2234)
                     /locus_tag="KRH23_002151"
                     /EC_number="3.4.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="leucyl aminopeptidase"
                     /protein_id="HHS5225429.1"
                     /translation="MNIKYSKEILKSLENAITVVALFEGEDVSTTFDKINMISRNFNS
                     KENSIDTVTLVENNNLVNVCLVGFGKRELLNREKIRIIGGNLCKKLKNILKNEAYKSS
                     DVNVLNLNLNSDEIGCFVEGILLGNYKFDKYKTKSKDFERKEVDTITIFTEKEVECQI
                     EKAKILANSTIIARNLVNEPSNVIYPKTLAVETVKLGAEFGFNVDVYEEEKIKALGMD
                     AFFAVSRGSINKPRFIVMRYFGDKESTDILGLVGKGLTYDTGGYSLKSNASMLDMKTD
                     MAGAASVIGAMCAISQSKLKKNVIAVVAACENALSGGSYKPGDIISSMAKKTIEVLNT
                     DAEGRLTLADAIYYIINNEKVTKVVDVATLTGAALTLLGNVATPIVTNNDDFYCELEK
                     AATLSGERVWKMPIYDEFKDMIKGEEADLKNTGGKNAGCITAGAFIGEFVGNTPWIHM
                     DIAGTSTSSKSIGYKAKGATGEPVRTLYYLAEI"
     gene            complement(2250..2690)
                     /locus_tag="KRH23_002152"
     CDS             complement(2250..2690)
                     /locus_tag="KRH23_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HHS5225430.1"
                     /translation="MSDKELSILLLESMNNFHNLIKIINNERYKKDKVLTERQFFALV
                     KIRKHDKIELKNLSRDLHVSTSSLCILLNKLVEQEYVYREEDSRDRRNTFYGITKNGE
                     KILDNEILKFVSIISDKMDCLDIDNKDKLFTSLEESKNIIEQLF"
     gene            complement(2938..3366)
                     /gene="ytfJ"
                     /locus_tag="KRH23_002153"
     CDS             complement(2938..3366)
                     /gene="ytfJ"
                     /locus_tag="KRH23_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GerW family sporulation protein"
                     /protein_id="HHS5225431.1"
                     /translation="MRATGSIQSLMETTLETIKGSIDANTIIGDPIKTDTTVVVPISK
                     VTIGFGIGGGEYSKGYDDKDREIELKNEKSDTNFAGGSAGAISVQPVAFVVVESGETR
                     IMSLDSNINLVDNILSITPRVLEKIQNISQSNKNQDKNNM"
     gene            complement(3320..3949)
                     /locus_tag="KRH23_002154"
     CDS             complement(3320..3949)
                     /locus_tag="KRH23_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2953 domain-containing protein"
                     /protein_id="HHS5225432.1"
                     /translation="MELNELFNFKYLIIAVIFIISVTMLILISHINILIIADIKNKDI
                     CLKLNIKYMFNLININRQLYPAENSKNNDKKEGMKNNIDSSILLADDLLSIYRLLKKI
                     KIHELYSNINFGTGNIGLTSSVYVLINTLYGNLFNMIDAEKMYLNVNPDFTKDYVLGN
                     IRIHIRPRIKALFNIIIMINKIMNKNKGNKEGDSNESNRFDTESYGNNS"
     gene            complement(4111..4650)
                     /gene="scpB"
                     /locus_tag="KRH23_002155"
     CDS             complement(4111..4650)
                     /gene="scpB"
                     /locus_tag="KRH23_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HHS5225433.1"
                     /translation="MKREDIKYIIESVMFAYGEPISIKELNYIINKELSSKEIEIMLN
                     LLIEEYREQNRGIQIIKLENKYQMCTNKDYAEYIKKIIEPKKKKSLSQATLETLTIIA
                     YKQPITKVEIEDIRGVKCDKVLQTLFENELIREAGRLNKIGKPIIYKTTDEFLKLLNI
                     ESLEELPPIENYQEVATNE"
     gene            complement(4652..5371)
                     /locus_tag="KRH23_002156"
     CDS             complement(4652..5371)
                     /locus_tag="KRH23_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="segregation and condensation protein A"
                     /protein_id="HHS5225434.1"
                     /translation="MKYNIQLQVYEGPLDLLYDLITKHKIDIKDISIIDITKQYLNYL
                     KMLDKMDLEITSEFITMASKLLEIKSKYLLYKQKDEEEDPRIELMEKLEEYRKFKVAS
                     QDIKENITYVNERFYRNKEEIIIDDNVDLEDISIEAIKNILPYIFKVKTSQIENANDE
                     KLDKIVRKKIISVEEKILYIRDIIKDKIEVTFTNIIKSYENDEIIATFLSILELIKEK
                     EIVVVQDIFFDDILIRKSSEC"
     gene            complement(5401..5997)
                     /locus_tag="KRH23_002157"
     CDS             complement(5401..5997)
                     /locus_tag="KRH23_002157"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008237 - metallopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HHS5225435.1"
                     /translation="MLSMNIGEIVASLVGIAMAISIHEFGHAYSAHLLGDDTAKAYGR
                     MTLNPVRHVDPIGLLAMFILKIGWAKPVPVNPNNFKNYKIGNLIVSLAGVFCNVLTAI
                     LCVIINKYVHMYAINTIAGYVLLYSMGFAAFNLLPIPPLDGWGVISTFVPYKWNEYLY
                     KFESMSYIILLIALFTGIYQIILSPIYTVLLKIVYLFV"
     gene            6295..7131
                     /locus_tag="KRH23_002158"
     CDS             6295..7131
                     /locus_tag="KRH23_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHS5225436.1"
                     /translation="MRQEERTVCFDRELKIEAYRFKGIMQKFPNHFHEHYVIGFIEKG
                     QRYLSCKNKEYTTSTGDLLLFNPFDSHTCEQIDDKVLDYRCINIKPEIMKKTVFEITG
                     KNYLPKFNQPVIFRSELVPLLQELHYIIMEEELDFKKEELFFFLIEQLIEEHTEPNLQ
                     SNLENTNIEIQAVCDYLENNYAEHIVLDELSTIAGMNKYSLLRNFTKLKGITPYRYLE
                     NIRVNKAKKLLEKGVEPIDAAIQTGFVDQSHFTNFFKNFIGLTPKQYQNIFINDDSNN
                     FK"
     gene            7152..7574
                     /locus_tag="KRH23_002159"
     CDS             7152..7574
                     /locus_tag="KRH23_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2000 domain-containing protein"
                     /protein_id="HHS5225437.1"
                     /translation="METKNSKCVMVIDENLPMGIISNTAAIMGITLGKHAPETVGPDV
                     IDKTGNSHLGIIDIPVPILKGNKEIIKDLRKKLYTLEFNDLTVVDFSDVAQSCNLYEE
                     FTQKIASVPEDELQYFGIAIYGNKKKVNKLTGSMPLLR"
     gene            complement(7785..8948)
                     /locus_tag="KRH23_002160"
     CDS             complement(7785..8948)
                     /locus_tag="KRH23_002160"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase family
                     protein"
                     /protein_id="HHS5225438.1"
                     /translation="MKKLASTALAILIALTPLSFSFANNKENADANQLNISSKSAILM
                     DVGSGQILYEKDAHKKLPPASVTKVMTMLLIVEALDSGKIKLDDEVQVSETASSMGGS
                     QIFLEPGETQKVDTLLKGIAVASANDACVAMAEHLAGSVEGFVDRMNAKAKELNMNDT
                     HFANTNGLPVANHYTSAHDIALMSRELLKHEMISKYLTTWMDKVVVGKKQVTVGLANT
                     NKLIKHYQGSTGVKTGFTQEAKYCLSASAKRGNTHLVAATLGAETSPERFNDASSLLN
                     YGFANYESVKLCSKGDNIATLTLDKADENKVKLVAKEDLNALIKKGSSKEFEKKIEIV
                     KNPKMPIKKGTVLGKIKICKDKKVIGEVELINTKDINKASYLQMLQRIIDNMI"
     gene            complement(9002..9202)
                     /locus_tag="KRH23_002161"
     CDS             complement(9002..9202)
                     /locus_tag="KRH23_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CD1290 family small acid-soluble spore protein"
                     /protein_id="HHS5225439.1"
                     /translation="MDDVSRQNAIKALKQTKMEIAGEYGMNYEDAFEIIENASNKGVL
                     EGYFKKLEKKKNLGQGISRHLE"
     gene            complement(9409..11085)
                     /locus_tag="KRH23_002162"
     CDS             complement(9409..11085)
                     /locus_tag="KRH23_002162"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004521 - RNA endonuclease activity
                     [Evidence IEA];
                     GO_function: GO:0004534 - 5'-3' RNA exonuclease activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HHS5225440.1"
                     /translation="MQLFKKNTNKIKVMALGGLNEVGKNMTVVEYKDEIIVIDAGLSF
                     PEDEMLGVDIVIPDITYLVKNRDKIKGIFITHGHEDHIGALPYILKKINVPVYGARLS
                     IGLIQVKLKEHKMNNVKLNVIGPRQVIKLDNMEVEFLKNNHSIPDAYSIAIHTDQGII
                     YHTGDFKIDLTPIDGDVMDMHRICELSKKGVLLMLADSTNAEKPGFTMSEKTVGVGLD
                     ELFAKGNGRRIIVATFASNIHRLQQIINTAEKFNRKVAISGRSMVNVVGVAKELGYLD
                     ISDDMLIDLNDICKYEDSELVIITTGSQGEPMSALARMAFSEHKKVEIKSGDLVIISA
                     HPIPGNEKLISRVINFLFEKGAEVVYSDIADIHVSGHACQEELKLIHALVRPKFFMPA
                     HGEYRMLKRHAEIAEQLGMDKENIFVMQTGDVLELDKNSAKVANRIQTGNILVDGLGV
                     GDVGNIVLRDRKHLSEDGLMIVVVTISKDEGKVLAGPDIISRGFVYVRESEDLMDGAK
                     DIIKNVLNECEEKNIKEWAYLKNNIKENLKEYLYQKTKRNPMILPIIMEV"
     gene            11302..12039
                     /locus_tag="KRH23_002163"
     CDS             11302..12039
                     /locus_tag="KRH23_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HHS5225441.1"
                     /translation="MRGKTHCAIGILTAIQTSLIFKIPISLVDILVSATFAVLPDLDK
                     SNSMVSNFILKNNVSKYIYRIFIYAVNIIIFFISININDNFYLSAIITFVAIIIIEAK
                     LTHTFLRKVFLSLIFILLAICLYIIEVEIYFTIFCLMLSIFPWLKHRSFSHSIFATII
                     VYFLLKQIELITNINNLSFYGTIGYASHMFLGDLFTKQGIPIFYPLSEKKISLGFLTV
                     GGPFSNFIEKSFIFVLIGLIIFSILKL"
     gene            complement(12156..12614)
                     /locus_tag="KRH23_002164"
     CDS             complement(12156..12614)
                     /locus_tag="KRH23_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fur family transcriptional regulator"
                     /protein_id="HHS5225442.1"
                     /translation="MANTMDLLKDKLKETGFKITPQRRAIVEILLKHDHSHLSSEEIY
                     DLVRVDCPEIGLATVYRTMQLLDEIGLISKLNLDDGCIRYEISLHKEDCHNHHHLICK
                     NCGKIMEAKEDLLDNIEKEIQSLYKFKILDHDVKFYGLCDECNGVSDSEE"
     gene            complement(12896..13183)
                     /locus_tag="KRH23_002165"
     CDS             complement(12896..13183)
                     /locus_tag="KRH23_002165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HHS5225443.1"
                     /translation="MEENIINLIDENGVESQFEIILTLEAEGKEYAILMPLDDEEAEE
                     ALIFRIDEDEEGEILIPLESDEEYETVVAVYTAIMEEEGLNYDEDESNGLN"
     gene            complement(13261..13686)
                     /gene="ruvX"
                     /locus_tag="KRH23_002166"
     CDS             complement(13261..13686)
                     /gene="ruvX"
                     /locus_tag="KRH23_002166"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HHS5225444.1"
                     /translation="MLDGRIMGLDVGDKTIGVAVSDLMGLTAQGVKTIKRVGKKKDIE
                     ELKAIIKEKQVNKIVSGLPKNMNGTLGPQGEKVIKFCELVKAETGIDVEFWDERLSTV
                     AAERSLLEADVSRQKRKKVIDMLAAVIILQGYLDFKINS"
     gene            complement(13892..16063)
                     /locus_tag="KRH23_002167"
     CDS             complement(13892..16063)
                     /locus_tag="KRH23_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5225445.1"
                     /translation="MRKKIMSLFAIVIMIFVSTASYGFAEEKGKVIFIDMNRTNLGSM
                     MNIPILKNEIEKRGYVALMNIRGDQGTDDRRSYASMGAGTRASVTTEDYINFQKVDQD
                     TAKAFEVATGQKAKEINDLGINRSINENLEYGEYGANLGSLGKTLSENGLKTSVIGNA
                     DIIENNQLVKNRNLCLVAMDQYGRIDSGNIDNINKKDSKMPFGISTDYDKLLDETKKS
                     YKNSDAIFVELGDTYRLDMYRLNLNDNTYDTMKKNIVKNINKYLEQVFSMVGENDTVY
                     IASAFPSDLDYKNKRRLSPIIKFSGEGKGLLESATTRKAGIVANLDVGVDILGTFGLE
                     NKEMVGRSYTLVNKEDNISYLKSLYERIVSISSIRSTIINGFVGVISASWVIAMFAIF
                     FRNYMPHKERVFKVLKEFIKLGIIMPLSFMLAPLMNFKTPISISLGIFATTLILYLLG
                     RKLFKDNDIKHMGFFATLTILVIVIDSVFGTYLMQNNIMSYDAVIGARYYGVGNEYEG
                     VTIASAVFGLAVLLHYKKVSKLLVVIFSLIILITSAYPSMGANVGGAISECVAYLLFI
                     MLIYDIKIDFKKAVLLAVSAVVVVFAFAALDILSGSESHLGMFVQRIFLNGPGEILQT
                     FGRKIQMNMQLAQTSVWVNILLVGIGVIAVLIFKPSRHFRKIMNNFPILFKGFIASMV
                     GCIITLLVNDSGIVAASTASIYILIPLIIISINMIIFEKNN"
     gene            complement(16073..16330)
                     /locus_tag="KRH23_002168"
     CDS             complement(16073..16330)
                     /locus_tag="KRH23_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HHS5225446.1"
                     /translation="MEKDLDYTMKFEGIPEDRMSVGDTIDFVYKALVEKGYNPINQII
                     GYLLSGDSSYITSHKNARAIIKKFERDEILEEVITHYLNRK"
     gene            complement(16355..18994)
                     /gene="alaS"
                     /locus_tag="KRH23_002169"
     CDS             complement(16355..18994)
                     /gene="alaS"
                     /locus_tag="KRH23_002169"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004813 - alanine-tRNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006419 - alanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HHS5225447.1"
                     /translation="MEKMGLNEIRSKFLEFFESKGHYVANSYSLVPNNDKSLLLINSG
                     MAPLKNYFSGVEVPPSVRMCTSQKCIRTGDIENVGITARHATFFEMMGNFSFGDYFKR
                     ESIKWGWEFVTEWLNIPEDKIWVTVYEEDDDSYDIWAKEMNFPEERMVRLGKDDNFWE
                     IGTGPCGPCSEIYFDRGEEYGCDNPDCKPGCDCDRYLEFWNHVFTQFDRDEEGNYSLL
                     ENKNIDTGMGLERMGCIMQGVDTIFEVDTIKSILEAVEKLTGVKYGENPKNDISIRII
                     TDHIRAVTFLVSDGVLPSNEGRGYVLRRLLRRAARHGKLLGVKELFLQKLIDEVIKVN
                     DKAYPVLVEKESYIKKVVGIEEEKFNETIDQGTEILNSYIEVLKNEGKTVLSGQEAFK
                     LYDTYGFPIDLTKEILEEEHLSVDEEAFNEEMEKQKERARNARGNMDGESWKEDPLSK
                     LESTVDSTFNGYSEIYGEGTIEAIVKDDELVQSAEEGDKVSIVLDNTTFYPEGGGQVG
                     DCGLITNENLVLEVLNTKKGANNSIKHIGIIKSGRISNGDKVKTLVDRETRMSAARNH
                     SATHLLHKALREVLGEHVNQAGSLVTPERLRFDITHFEAISNEELKVIEEKVNNVILS
                     SLDIKCDIMNIKEAKEKGATALFGEKYGDEVRVVSMGDYSTELCGGTHLTNTSQVGMF
                     KILSEGGVAAGVRRIEAITGKAVYEYLKERDGIISEVCVNLKSKEDNLIQRISSLLEE
                     NKNLSKELHDMKAKMSLQSVDSIFDSKVEVNGVNLITNKFEGMDMDTLRETADNLRDK
                     LGSGVVVLANVVDDKVNFVVTATKDVLDKGIHSGNIVREVAKIAGGKGGGRPNMAQAG
                     ASDVSKVDQALSYASEVIKTQVK"
     misc_binding    complement(19062..19300)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(19443..20522)
                     /gene="mnmA"
                     /locus_tag="KRH23_002170"
     CDS             complement(19443..20522)
                     /gene="mnmA"
                     /locus_tag="KRH23_002170"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016783 - sulfurtransferase activity
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HHS5225448.1"
                     /translation="MNKKVMIGMSGGVDSSVAAYLLKQQGYDVIGVTMKLWQDDDVVE
                     IEGGCCSLSAVEDARRVANKIGIPFYVLNFREVFKEKVIDYFIDEYLEGKTPNPCIAC
                     NKHIKFDDFYKKARQIGCDYVATGHYAKIEKDESTGRYLLKKSVTDKKDQTYALYNLT
                     QEQLEHTLLPIGDYEKDRVREIAKEMGMAVHNKPDSQEICFVKDNDYANYVKKHSKKR
                     IEEGFFVDTKGNILGKHKGILYYTIGQRKGLGITFGKPMFVIDINPINNTIVLGDNED
                     LFKKELIAKDVNFISIDTLEEPLRVQAKIRYSAKPSPATIHRVGEDTIKIVFDEAQRA
                     ITKGQSVVMYDGDIVVGGGIIEKSL"
     gene            complement(20811..21251)
                     /gene="nifU"
                     /locus_tag="KRH23_002171"
     CDS             complement(20811..21251)
                     /gene="nifU"
                     /locus_tag="KRH23_002171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly scaffold protein NifU"
                     /protein_id="HHS5225449.1"
                     /translation="MQYSDKVMEHFMNPRNMGEIDNASGVGEVGNPTCGDIMKIFLDI
                     DGDVIKDVKFKTFGCGSAIASSSMATEMIKGKTIKDALELTNKAVAEALDGLPPVKMH
                     CSVLAEQAVKAALIDYAQKNNIHIPELDGYVIDDAHDHDVEEEE"
     gene            complement(21305..22498)
                     /gene="nifS"
                     /locus_tag="KRH23_002172"
     CDS             complement(21305..22498)
                     /gene="nifS"
                     /locus_tag="KRH23_002172"
                     /EC_number="2.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0031071 - cysteine desulfurase activity
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase NifS"
                     /protein_id="HHS5225450.1"
                     /translation="MEKRRLYMDYSATTPIKKEVLDAMMPYLTDYFGNASSFHTFGRE
                     AKDALDKAREQVAALINAEPSEIYFTAGGSESDNWTLEGVAYANKNKGNHIITSKIEH
                     HAILHTCEYLAKHHGFEITYLDVDSEGKVDLKQLEDSIKDTTILISIMFANNEIGTIQ
                     PIKEISEIAKKHKILFHTDAVQATGNIPVDVKELGIDLMSMSSHKIYGPKGVGALYIR
                     KGVRLHNFVHGGAQEKSKRAGTENIPAIVGYGKAAELAKENMQNHVETLTRLRNKLID
                     GVLERIPYTRVNGSLENRLPGNANFAFQFIEGEGILLLLDMLGIAGSSGSACTSGSLD
                     PSHVLLAIGLPHEIAHGSLRLTVGDFTTDDDIDYILENLPKVIERLRSMSPLYDDAKK
                     QGLVK"
     gene            complement(22516..22962)
                     /locus_tag="KRH23_002173"
     CDS             complement(22516..22962)
                     /locus_tag="KRH23_002173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RrF2 family transcriptional regulator"
                     /protein_id="HHS5225451.1"
                     /translation="MKLSTKGRYGLKAMFELALNQDNGPVSLKFIAKKQKISDQYLEQ
                     IFSSLKKSGLVKSVRGAQGGYLLSKNAEDITVGDILVVLEGPVALSDCVLDEDVCENS
                     NMCVTKIVWEKMKKGIEDVIDSITLKDMINDYNKNKLENDITNIKK"
     gene            complement(23071..23841)
                     /locus_tag="KRH23_002174"
     CDS             complement(23071..23841)
                     /locus_tag="KRH23_002174"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HHS5225452.1"
                     /translation="MIIKLNSTYHSRVMKYLKKEPEYNLFIIGDIERYGYGNNFLNIW
                     ADVGEHGEIKAILLKYFEFMMFYSDGEYDVEGFYNLLRNTNYEEISGKICAVDALAKR
                     LGLNNLKVVDFCKLQTKKFLIDNNCNAKVKRIRLGNLKKTVKLYDLIDEFHSTTLENL
                     KNGLRTGRGYCIEINKQVVSMAKSTSENRTHAMIIGVGTHPKYRAKGLATKCLIKLCS
                     ELLRENKIPCLFYDNEEAGKIYKKLGFENIGKWGIYSK"
     gene            complement(23872..25137)
                     /locus_tag="KRH23_002175"
     CDS             complement(23872..25137)
                     /locus_tag="KRH23_002175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HHS5225453.1"
                     /translation="MPLADKIRPKTMNDVIGQSHIIGNGKILSKILQSNFLPNMIFFG
                     PPGVGKTTVAEIIAERSNKSFYKINATNSSLEDIKKVISELGSINNVNGVLLYIDEIQ
                     SFNKKQQQSILEFMENGSITLIASTTENPYHYVYKALLSRSTVFEFKPLEKLDIEKGL
                     KRAVEVLNEDSYMDIECNNDAIEDIAILSDGDMRRALNILEVVVYSTKPNKDNITYID
                     SDVIRASTFNKIINYDKNGDSHYDILSAFQKSIRGSDPQASIHYLARLIKGGDLISIC
                     RRLLVIASEDIGLAYPNAIVIVKACVDSAMQLGFPEAKIPLAEATILLATSPKSNSAC
                     IAIMKAMDELDKEFVKDIPNSIKDAHYSGSKEIGRGCGYKYPHNFKNHYVKQQYLPDS
                     IKDSIYYIPQENKTEKNIKKYLEYLNSDF"
     gene            complement(25244..26029)
                     /gene="codY"
                     /locus_tag="KRH23_002176"
     CDS             complement(25244..26029)
                     /gene="codY"
                     /locus_tag="KRH23_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HHS5225454.1"
                     /translation="MASEVLQKTRKINKTLQTSGGSSVSFDLLAGALGDVLSSNVYVV
                     SAKGKVLGLHLNDVQDSSVIEDEYTKQKKFSDEYTQNVLKIDETLENLNGEKILEIFP
                     EEHGRLQKYTTVVPILGSGQRLGTLVLSRYSNSFNDDDLVIAEYSATVVGLEILRAIG
                     EELEEEMRKKAVVQMAIGTLSYSELEAVEHIFAELDGKEGLLVASKIADRVGITRSVI
                     VNALRKFESAGVIESRSLGMKGTHIRILNDKLTDELKKLKNNQ"
     gene            complement(26194..28281)
                     /gene="topA"
                     /locus_tag="KRH23_002177"
     CDS             complement(26194..28281)
                     /gene="topA"
                     /locus_tag="KRH23_002177"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HHS5225455.1"
                     /translation="MAKTLVIVESPAKAKTIEKFLGKSHYTVKASVGHVRDLPKSKLG
                     VDIENNFEPQYINIRGKGDVIKELKKEAKKSKQVYLATDPDREGEAISWHLAHILNLD
                     ESEDCRIEFNEITKDAIKKAIKHPRNIDINLVDAQQARRVLDRLLGYQISPILWQKVR
                     KGLSAGRVQSVTTKLICDREKEIKAFIPKEYWTIDVEAKTVKDKDITLKFYGKNDEKI
                     ELENEEAVNEILKEMEGKDLKVEKIESKSRRKSAPKPFTTSMLQQEGANKLFFTTKKT
                     MMIAQELYEGIDIEGEGTVGLISYIRTDSKRISDEAKEKAKGYIVNNLGENYYKNTGD
                     KKEKKDTKKVQDAHEAIRPTSVDRTPESIKASLSKDQYKLYNLIWRRFVASQMEDSVF
                     DILNVECKIGDIVFKATGSKMKFDGYTKVYNFSEREDKILPSIEKGDILNIENILPDQ
                     HFTQPPARYTEASLVKTLEELGIGRPSTYAPTIATILNREYVEKQGTSLCPTELGIIV
                     TDILENNFHKFIDVDFTADMESKLDVIEEGNTDWKKIVSESYAPLKEAIEEALENIEK
                     VNMDEETDEICENCGSNMVIKYGRFGKFMACKNYPDCKTTRPIMNKIGVKCPKCEEGD
                     IILRKSKRGKAFYGCSNYPNCDFVAWNKPTGEFCEKCGSYMVEKVTKSETKTVCSNKE
                     CNKETKEHNDGKE"
     gene            complement(28314..29414)
                     /gene="dprA"
                     /locus_tag="KRH23_002178"
     CDS             complement(28314..29414)
                     /gene="dprA"
                     /locus_tag="KRH23_002178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009294 - DNA-mediated transformation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-processing protein DprA"
                     /protein_id="HHS5225456.1"
                     /translation="MEKRDTYLWLKSIGGITTKTIEIIENEIVNIEDIFDFSEKEIYN
                     LKNISLNIRKNIVKYRGHAYLENIKELLYKKAIKYICKYDKEYPENLKNIYNAPKLLF
                     YKGDIGLVNNNFNIAIVGSRKPTAYGINCAKTISCQLSQYGVNIVSGLAIGIDAYSHI
                     GCMSGKSKTIAVLGSGVDNPLPKQNLHLSNKILENGGLLLSEYNINSTVAPYHFSNRN
                     RIISGLSDGVVVVEAAIKSGALITVDFALEHGKNVFAIPGNINSQMSRGCHKIIKEGA
                     KLIENIDDILNEYNIFNIIDKKINQKYDNISLNAKSKQIIEAIKREGNLHIDSICDYT
                     GIEIKYVNSIINELVLNELVVEMNNKTYSLNV"
     gene            complement(29433..31034)
                     /locus_tag="KRH23_002179"
     CDS             complement(29433..31034)
                     /locus_tag="KRH23_002179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YifB family Mg chelatase-like AAA ATPase"
                     /protein_id="HHS5225457.1"
                     /translation="MLSIINSSNLVGIDSFLVKVEVDVSNGIPSFNIVGLPGKEIKEA
                     RERVKSAILNSGYKFPSTRIVVNLSPADIKKEGAFLDLSISIGLLRELIKKDENYIRE
                     SMFIGELSLDGKIRKVRGILPIIMGAKTQNIKRIFIPIENIKESLFVDEIDIIPIKSL
                     KECVDFLNEEIKVDKVRIMSFLDDKSRKENEELEKDNSYIDCKYTKINNEESKYDEDF
                     KDVKGNYFVKRSAEIAAAGNHNMFMIGPPGSGKTMIAKRVRTILPDISVEEMIEVSKV
                     YSILGMINETKGIIDKRPFRAPHHTTTKQSLIGGGMDARPGEIALAHRGILFLDEIAE
                     FDRKILETLRQPIEDGYVNISRVKYSAKYPCRVLLVAAMNPCPCGYYMSETECRCRSN
                     EIDRYINKISGPLLDRFDIFVEVNSIKYSDFNSLKQEESSQKIKRRVENARKIQINRF
                     KKDNIKNNSEIKAYNLFKYCKLEKEASKTAEMIFNKYNLSSRSYTKLLKMARTIADLE
                     ERDLINSQCIIEAFSFRKAYYSYFK"
     gene            complement(31065..31409)
                     /locus_tag="KRH23_002180"
     CDS             complement(31065..31409)
                     /locus_tag="KRH23_002180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YraN family protein"
                     /protein_id="HHS5225458.1"
                     /translation="MNNKEKGDFGEKVAVNYLLSKGAKILEKNYRLKIGEIDIIAKME
                     DEIIFVEVKSRSNIKFGYPCESVSFKKRKKIIGVASYYIIKNNLNNTPIRFDVIEVYL
                     LEKRINHIMNAF"
     gene            31593..32756
                     /locus_tag="KRH23_002181"
     CDS             31593..32756
                     /locus_tag="KRH23_002181"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HHS5225459.1"
                     /translation="MNREKLVAFIRYLSLFILVVSYLKNVENTLYPVITMIILFLIII
                     NNQVRFFSLSNENKFILISYFLELILIFILCNYTKTFNSIYFVPLILDISFLIKEKYK
                     YILFSFVIISSLIISLDKNIYLALESSSILLIITVLSIYIENENLSKLYSQNLYDKLR
                     ISKDELKKVNADLETYASSIEELAILKERNRISREIHDSVGHSLSTTIIQLNAIEKLL
                     KDKPLIYDLVHELREFVTESFQDVRRAISELKPVEYENYQSLFKIKELVKSFIKLTNI
                     NVKLTISKNTWNLSRNQSIALYRLIQESLSNSSRHGKATEIRIFITFNTSNLIITISD
                     NGIGCGNIKKGNGLNSINERIYELNGKVEFDNSNNGFTIRASFPKFSGGDFFE"
     gene            32749..33396
                     /locus_tag="KRH23_002182"
     CDS             32749..33396
                     /locus_tag="KRH23_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HHS5225460.1"
                     /translation="MNKIKVLIVDDEKLIRKGLKIILSSYNDLEIVGDASNGYEALEF
                     CKMNDVDIVLMDIRMKVCDGVLGTRLIKEYNNSITLLILTTFNDDEYIKDAMKFGASG
                     YLLKDSSDEVLHEGIRSSFFGNIVLDKSVAEKIMTSEKTVKQEHLYDMYNLTEKEISI
                     IRLIANGLNNKEISQELFLSEGTIKNNITNILAKLELRDRTQLAIFAFKNKIVIE"
     gene            33525..34460
                     /locus_tag="KRH23_002183"
     CDS             33525..34460
                     /locus_tag="KRH23_002183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HHS5225461.1"
                     /translation="MDIVRVNNITKRFNDKLVLDNISFSVKKGEIFGLIGPNGAGKST
                     LINIITNLMLPNSGSIQINGLDLSKDYIKAKSIIGLVPQELAIIETLTPFDNLEYFGA
                     FYGLKGKLLKERIIEALEVTGLTEVKKKKVKKLSGGMQRRLNIGIALLNHPKILILDE
                     PTVGVDPQSRNHIFNFIKDISKKHETTVIYTSHYMEEVEHLCSKIFIMDEGKEIAFGD
                     NDYLKSLVSTNTKLILEIKNINAQLIFDLKNTKGVISVLENNSLLELDIDKKLQLTDI
                     LSIIDKNDSKIMKISYEEPSLEDVFLNLTGKNLRD"
     gene            34474..35571
                     /locus_tag="KRH23_002184"
     CDS             34474..35571
                     /locus_tag="KRH23_002184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHS5225462.1"
                     /translation="MKLYMSVKTMLKGLKSSFILNLIYFLALPLILSWFLGMVTESMF
                     QNPIKTESTPIVIYDKDNTRLSNDLTKYLKNDLSYILTVKKDDSKAELKLTIPKGYES
                     SLLNEKSNTLNIEKLGTRDDIAILLQDILDTYHEKFYLNNSQKISSEDFSKLFNKNSI
                     DTSIINNNVKQSSYEYFALVSLGFLVIIFIMNNILSNYISESKGLSKRLYSMPITRVQ
                     FLIYDFVGLWIYSFIFLLLYVLFFRILGITFKGNFAILLLLCALSSYFMTSISTFVTS
                     FFSKKYGTAIVYALLFLQTIFGGIFSMISDTFTKLTSLSPTYLIGELFSNYETFKTID
                     SIGNLIFTCLIISTILIALAIVKEKYKWREV"
     gene            35574..36638
                     /locus_tag="KRH23_002185"
     CDS             35574..36638
                     /locus_tag="KRH23_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHS5225463.1"
                     /translation="MIRLTIANIKRYLKNHTLLINMVMLPIILIFSLNFFINNSGNQS
                     MYFSPVAIVSDSSGKYEHKLINSSKLKENSFRLNEQDKAMNLLKNNKVSAVFVLDKNF
                     SNSIDKLQRPVVKCFKIENGGGSLWAESQIESFITKSLKLKVDKNIDDKLTKTNIIDN
                     KPAKNKGSFLVVFLICYFMYINAAHLASDLFTLKKSNVLKRLISTDNKDIKIIFSIFL
                     GLFFIQSIVYTFALLCFSIIEDFNLSLNVLMIVLANSFVSTGFVFWVARVFKNESSIS
                     LISTFYSLIGLAISISSLIPSMDKLSFMTNLSKFTPFYWTIDAIKNNGSILINIIALI
                     LIGIIFVTAGSLKLRDFAKN"
     gene            36882..37379
                     /locus_tag="KRH23_002186"
     CDS             36882..37379
                     /locus_tag="KRH23_002186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140110 - transcription regulator activity
                     [Evidence IEA];
                     GO_process: GO:0009303 - rRNA transcription [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CarD family transcriptional regulator"
                     /protein_id="HHS5225464.1"
                     /translation="MYKIGESVMYPKEGACSVNDIVTKKINHEMQKYYELSVIFNSNL
                     KISIPVLNADRIGIRPVMDGNDVDNFIQSINKTDGVWIFDRKERLKLYQDKFHSGDVF
                     EIVKLIKMLMIQDSSKQLCSTDKEFLNKAQKFALSELAAAQCKSYTMVLEEMKKHILN
                     SKNIN"
     gene            complement(37555..37803)
                     /locus_tag="KRH23_002187"
     CDS             complement(37555..37803)
                     /locus_tag="KRH23_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5225465.1"
                     /translation="MSRKAYEEALVELEKFIDERKEIIKSAEDCIDKYIVDRTLPFDY
                     KDKCVEWQQELLDIAEAQVLEANELSVLLQEKKELEED"
     gene            complement(37869..38885)
                     /locus_tag="KRH23_002188"
     CDS             complement(37869..38885)
                     /locus_tag="KRH23_002188"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HHS5225466.1"
                     /translation="MEYNELLKSARENLNGSCKVCKVCNGVACAGEVPGMGGKGSGSS
                     FIENSKSLEKVKVNMRVIHDVSNPDTSIEMFGKKMSAPIFAAPVTGTTLNMGGKINER
                     DYIEPVVAGCANSGIYAMVGDTAVDAFLMENLDVVKKYNGAGIVFIKPWDNENIIKKI
                     RLAEEAGAFAVGVDIDACGLVTLSLHGKPVLPKNVKQIKELVKSTKLPFILKGIMTVE
                     DTLMAVEAGVDAIVVSNHGGRVLDCTPGACEVLPKIADAVKGKVTILADGGVRTGLDV
                     LKMIGLGADAVLIGRPFVTASFGGATDGVETYVNKLQSELSSSMILTGCQTIKDIDGK
                     VIYK"
     gene            complement(38943..39710)
                     /locus_tag="KRH23_002189"
     CDS             complement(38943..39710)
                     /locus_tag="KRH23_002189"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HHS5225467.1"
                     /translation="MQDKSVREIKEIIETLEVEKYMEYIELLRVDERKSVQGLAIKLA
                     KKLDNIRKEEERLETINIFENEGYDKGYLYIGGIDEAGRGPLAGPVVASVVVFKKDTK
                     IEGVNDSKKLSEAKRDELFEVIKEEALDYGIGIVNNEEIDEFNILNATYMAMKKAINC
                     LKKAPDYLLVDAATIPGIDISQNPIVKGDSKSISIAAASILAKVTRDSIMYQYDRVYP
                     EYGFKSHKGYGTKEHYEAIEKYGITPIHRKSFLKNIL"
     gene            complement(39778..41967)
                     /locus_tag="KRH23_002190"
     CDS             complement(39778..41967)
                     /locus_tag="KRH23_002190"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA];
                     GO_function: GO:0031419 - cobalamin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobalamin-dependent
                     ribonucleoside-diphosphate reductase"
                     /protein_id="HHS5225468.1"
                     /translation="MKYIIKRDGTKELFSKSKIEDAVYKASINSEGGVDRELAYDISR
                     KIANDYNSMEKCLSVEEIQDIVEVLLMESNRKDIAKHYILYRERRSEIRTKAWEFDEL
                     QKSIWKNKYRHNGESFDEWIKRISNNSSRISKLIRQKRFLFAGRILANRGLQKEGKKV
                     TYSNCYVIEPPKDSIEDIFDTAKKLARTFSYGGGVGIDISKLRPKGAKVNNAAKHTTG
                     AVSFMELYSMTTGLIGQRGRRGALMISMDVNHPEIEDFIDIKTDLEKVTKANISVRVT
                     DEFMQAVREKKLYNCTFEVETTGEKIVKIVNAYDLFNKFVKNNWDYAEPGILFWDKIK
                     TYNFMSEDKNFCFSGVNPCAEEPLPSGGSCLLGSINLSEFIIQPFGEHATFDINKLKS
                     CVREAVVALNDVLDEGLNLHPLQEQRDSVHKYRQIGLGVMGIADMLIKMGIRYGSDES
                     LELCDLIGKTMLNEAVKQSALIAKEYGTFSEYKYENISKSKFFIENLNEDTKEMVKKY
                     GLRNSQLLTIPPTGSISTMIGISGGIEPIFNLSYIRKTESLHDEDVYYKVYTPIVKEY
                     MDKKGITDEECLPDFFVTAMNIGYEERINMQKVWQKYIDASISSTINIPFETTVEDVF
                     NIYIKAWEAGLKGVTIFRDGCKRSGILINEKKEENNKEDKKENSKKEYYKNNKKEKDN
                     KDEKAKEIINKNFEEDEKFVCPECGSEGIAHTGGCSICLKCGYSGCN"
BASE COUNT        13472 a         7262 c         4462 g        16882 t
ORIGIN      
        1 tttattatag gagagaatgt tatatgttta aaatttttct tttttctagt gaacaatttg
       61 taagtctctt tatatttgga ttatttttat actattgtcc aaaactaacc aaaaatattt
      121 taccttatag ctatacagtt gagaagataa tttgtacatt acttgtaata attatggctc
      181 tagagcaatt attacttatt tcttcaggta attatagtac tctaaactct ttaccaattg
      241 gaatcaatta tatttgtata tatctgtgta tagccatact aatttttaag cagtatcatc
      301 tttttaatat atttttttct tggagtttag tttgttcagt tggagaactc attttttcta
      361 aaaacttggg ctatgaattt cctagcttaa tatattttat ctttatcttc tctaagtgct
      421 tgataattta tgcagatata tatatggttg atgttagaaa atttagagtt aacagatatg
      481 cacttagaga taacttagct atatgtttta tttatttttc attcatattt ttactaaaca
      541 catttaccaa ctctaggtac tattatggtt ttttaagtca tagcacaact gctattttta
      601 cgtttatttt tgttactagt attatgtaca tacctgctct tttatttaat agagatactt
      661 ttatacttga aaaaaagaaa aagagtaaat aatttattta aataaaaaat aaagccacat
      721 agataatctt aaattacaaa aatatccacg tggctttata aattatattt tataattgtt
      781 ttttagattt ctgccaaata gtacaatgtt ctaacaggtt ctcctgtagc cccctttgct
      841 ttgtatccaa ttgattttga tgatgtactt gtccccgcta tatccatatg tatccaagga
      901 gtattcccaa caaattcacc aataaaagct cctgctgtta tacatccagc atttttacca
      961 ccagtgtttt taaggtctgc ttcttctcct tttatcatat ctttaaattc atcataaatt
     1021 ggcatcttcc ataccctttc ccctgataaa gtggcagctt tttctaattc acaataaaaa
     1081 tcatcattat ttgttactat aggagttgca acattaccta acaatgttaa agcagcacca
     1141 gttaatgtag ctacatcaac cacctttgtt actttttcat tgtttataat gtagtatatt
     1201 gcatcagcta atgtaagtct accttctgca tccgtattta aaacttcaat agttttcttt
     1261 gccatagaac taattatatc tccaggtttg tatgaacctc ctgataaagc attctcacat
     1321 gcagccacta ctgctataac atttttcttt aatttacttt gagatatagc acacatagca
     1381 cctataacac tcgcagcacc agccatatct gtcttcatat ctagcataga agcatttgat
     1441 tttaaagaat atccaccagt atcataagtc aatcctttac ctactagacc taatatatct
     1501 gtactttctt tatctccaaa gtatctcatt actatgaatc ttggtttatt aattgaacct
     1561 cttgaaacag cgaaaaaagc atccattccc aatgccttta ttttttcttc ttcataaaca
     1621 tcaacattaa acccaaactc tgcaccaagt ttaactgttt ctactgctaa tgtttttgga
     1681 tatattacgt ttgatggttc attaactaga tttctagcta ttatagttga attagctaat
     1741 attttagcct tttctatttg acactcaact tctttttcag taaatatagt tatagtatca
     1801 acttcttttc tttcaaaatc cttacttttt gtcttatact tatcaaactt ataatttcca
     1861 agtaatatcc cttctacaaa acaacctatt tcatcactat ttaaattaag attcagtaca
     1921 ttaacatcac tactcttata tgcttcattt ttcaatatat tttttaattt tttacacaaa
     1981 ttcccaccta tgattctaat tttttctcta ttcaataact ctctcttacc aaaaccaaca
     2041 agacaaacat ttaccaaatt gttattttca accaatgtta cagtatctat actattttct
     2101 ttagaattaa aatttctgct tatcatattt attttatcaa atgtcgtaga aacatcttct
     2161 ccctcaaata gagctactac tgttatagca ttttctaaac tttttaatat ctctttagaa
     2221 tactttatat tcataataaa ttctcctttt taaaataatt gttctattat atttttagac
     2281 tcttccaaag aagtaaataa tttatcttta ttatctatat ctaggcaatc cattttatca
     2341 cttattatag atacaaactt tagtatttca ttatccaata tcttttctcc atttttagtt
     2401 attccataaa aagtatttcg tctatctcta ctatcttctt ccctatatac atactcttgc
     2461 tcaaccaatt tattaagtag tatacacaga ctagaagtag atacatgcaa atctctactt
     2521 agatttttaa gctctatttt atcatgtttt cttattttta ctaaggcaaa gaactgtctt
     2581 tctgtaagaa ccttatcttt tttatatctt tcgttattaa taatctttat taaattatga
     2641 aaattattca tactttctaa caacaaaata gataattctt tatcgctcat aacattcacc
     2701 tcaaaactaa tgatttataa ctccctctta tatctcaaat gcgtttatat atctataata
     2761 taatacttct tttcttttta taattatact atatatcaac tttattatct atttaaattg
     2821 ttttaaacta aaatcttatt agatataaat gtttaaagta cacaacaaaa tagtgggatt
     2881 tatattaacc ccactacttt acttaaaact atatacatat ttaaaaatat tttattctta
     2941 catattgttt ttatcttgat tcttattact ttgtgatata ttttgaattt tctccaatac
     3001 tctaggagtt atagataata tattatccac tagattgata ttactatcta aactcattat
     3061 tctagtctct ccactttcaa ctactacaaa tgctactggt tgtacagata tagcccctgc
     3121 gctacctcca gcaaaattcg tatctgattt ttcatttttt aattcaattt ccctatcttt
     3181 atcatcatat ccttttgagt attctcctcc tcctatacca aagccaattg taacctttga
     3241 tataggtaca accactgtag tatctgtttt tatagggtct cctataatag tatttgcatc
     3301 tatagaacct ttaattgttt caagagttgt ttccataaga ctctgtatcg aacctgttgc
     3361 tctcattact atcaccttcc ttatttcctt tatttttatt cataatttta ttaatcatta
     3421 ttataatatt aaataaagct tttattcttg gccttatatg tatccttata tttcctaaaa
     3481 cataatcttt tgtaaaatct ggatttacat ttaaatacat tttttctgca tcaatcatat
     3541 taaataaatt tccatacaaa gtatttatca atacatatac agaagatgtt aagccaatat
     3601 ttccagttcc aaaattaata tttgaataaa gttcatgtat ttttatcttt tttaataatc
     3661 tataaatgct caaaaggtca tcagctaata atatacttga atctatatta ttcttcatcc
     3721 cctctttttt atcattattt ttactatttt cagctggata aagttgtcta tttatattta
     3781 ttaaattaaa catgtatttt atattaagct ttaaacaaat atctttgttt tttatatcag
     3841 ctattattaa gatgtttata tgagatatta aaatcaacat agttacactt ataataaaaa
     3901 ttacagctat tattaaatac ttaaaattaa ataattcatt aagctccatg tttatattat
     3961 catcaaaaaa ttactattta tacttaatta tccatattta ttttaagaga attataattt
     4021 tatatttata caaaaaaaca caacaactta gagcatttta aatcttttaa aatttaaaat
     4081 tacatactaa attattgtga ttttatattt ttattcattt gttgccactt cttgataatt
     4141 ttctataggt ggcaattctt caagactttc tatattcaac aactttaaaa attcatctgt
     4201 tgttttataa attattggtt tccctatctt attcaatcta ccagcttctc ttataagttc
     4261 attttcaaac aaagtttgta ataccttatc acattttact cctcttatat cctctatttc
     4321 tacctttgtt attggttgtt tgtaggcaat tatagtaaga gtttctaatg tagcttggct
     4381 caaacttttc tttttctttg gttcaataat cttctttata tattctgcat agtctttatt
     4441 tgtacacatt tggtacttat tctctaactt gattatttga atacctctat tttgttctct
     4501 gtactcctca ataagtaaat ttaacataat ctctatttct tttgatgaaa gttctttatt
     4561 tattatatag tttaattctt ttatacttat tggctcacca tatgcaaaca taacagattc
     4621 tataatatac tttatatctt ctcttttcat tttaacactc cgaacttttt cttattagaa
     4681 tatcatcaaa aaatatatct tgtactacga ctatttcttt ttcttttata agctctaata
     4741 tagataaaaa agtagctatt atttcatcat tttcatatga ttttataata tttgtaaaag
     4801 taacttcaat cttatctttt ataatatctc ttatatataa tattttttct tctacagata
     4861 ttattttctt ccttactatt ttatctagtt tctcatcatt agcattttct atctgtgatg
     4921 ttttaacttt aaatatgtat ggaagtatat tttttattgc ttctattgat atatcttcta
     4981 aatccacatt gtcatcaata attatctctt ctttatttct ataaaatctc tcattaacat
     5041 aagttatatt ttcttttata tcttgtgatg ctaccttaaa ctttctatat tcttctaact
     5101 tttccataag ttctattctt gggtcttctt cttcatcttt ttgcttataa agcagatatt
     5161 tagactttat ctctaaaagt tttgatgcca tagttataaa ttcactagtt atctctaaat
     5221 ccattttatc tagcattttc aaataattta gatactgctt agttatatct attatagata
     5281 tatcctttat gtctatttta tgctttgtta ttaaatcata aagtaaatct aatggtccct
     5341 catagacttg taattgtata ttatacttca tatcaatccc tctttaatct gtttattata
     5401 ttaaacaaat aaatatacta tttttagcaa cactgtatat attggtgata gtattatttg
     5461 atatatacca gtaaataaag caattaataa aattatataa ctcatacttt caaatttata
     5521 caaatattca ttccatttat atggtacaaa tgtagatata actccccatc catcaagtgg
     5581 aggtatcgga agtaagttaa aagctgcaaa tcccatacta tataaaagca catatccagc
     5641 tattgtattt atagcataca tatgcacata cttattgata attacacaca gtatagcagt
     5701 caaaacatta caaaaaacgc ctgcaagtga aactatcagg tttcctatct tatagttttt
     5761 aaagttattt ggatttactg gtactggctt tgcccaccct atcttaagga taaacatagc
     5821 caaaagacct attgggtcaa catgtcttac aggatttaat gtcattctac cataagcttt
     5881 agctgtatca tctcccaaca agtgagctga ataagcatgg ccaaactcat gtattgatat
     5941 tgccatagct ataccaacta aacttgctac tatttctcct atattcatac ttaacattaa
     6001 tgtacatctc ctaaattaaa tttttaatat tattataaca attaaatagc ttataatcaa
     6061 aattatttta cattataata attttaactt ctaggcataa aattaaaatt tgctttttat
     6121 tttataactt ttattattat atcatattca ttgtgaaaat ataataatta cacctactgt
     6181 aagtataata ttatattgac atgaattgac attattgtct cttagtcaat attatacaag
     6241 aagtataaaa aaatatgtgt tacactttgt ataacatgaa aggaggttac ttaagtgaga
     6301 caagaagaac gcacagtatg ctttgatagg gaattaaaaa ttgaagcata tagatttaaa
     6361 ggcataatgc aaaaattccc aaaccatttt catgaacatt atgtaattgg ttttatagaa
     6421 aaaggtcaaa gatatttatc ttgtaaaaat aaagagtata ccacaagtac tggagatttg
     6481 ctacttttta acccttttga tagtcatact tgtgaacaaa tagatgataa agtacttgat
     6541 tacagatgta ttaatattaa gccagaaata atgaaaaaaa ccgtctttga aattacaggt
     6601 aaaaattatt taccaaaatt taatcaacct gttatatttc gcagtgagct agtacctcta
     6661 ctacaagaat tacactatat aatcatggaa gaagaattgg attttaaaaa ggaagagctt
     6721 tttttcttcc taattgaaca attaattgaa gaacatacag agccaaattt gcaatctaac
     6781 ttggaaaata caaatataga aattcaagca gtatgtgatt atctagaaaa taattatgct
     6841 gaacatatag tacttgacga attaagcact atagcaggta tgaataagta ctctctactt
     6901 cgtaatttta cgaaattaaa aggtattaca ccatatagat acctagaaaa tatacgggta
     6961 aacaaagcta aaaagctttt agaaaaaggc gtagaaccta tagatgctgc gatacaaaca
     7021 ggatttgtag accaaagtca ctttacaaac ttttttaaga attttatcgg tcttacacca
     7081 aagcagtatc aaaatatatt tataaatgat gattcaaaca actttaaata aggtaaaaag
     7141 gagaaataaa aatggaaact aaaaattcaa aatgtgtcat ggtaatagac gaaaatttac
     7201 caatgggaat tatatccaat acagcagcta taatgggaat tacactagga aaacatgccc
     7261 cagaaactgt tggcccagat gtaattgaca aaacaggtaa tagccactta ggaattattg
     7321 acattcctgt acctatttta aaaggaaaca aagaaataat aaaagattta cgtaaaaaat
     7381 tatatacttt ggaatttaac gatttaactg ttgtagattt ttcagatgta gcacaaagtt
     7441 gcaatcttta tgaagaattt acacaaaaga ttgctagtgt tccagaagat gagttacagt
     7501 attttgggat agcaatttat gggaataaaa agaaagtgaa taaacttact ggtagtatgc
     7561 ctttacttag ataattgtta aacaacccta tatatgatat taaatcaaat gatattttaa
     7621 gatacataaa cttttctata tttctataaa aatcataaga ttataaaata cttctatatg
     7681 gtaaataaaa atacccctat ggcaaataat tacataaggg tattttttat gtgtattata
     7741 atcatatctt tgtgtattat aattatattt catctgataa ttatttatat catattatca
     7801 attattcttt gaagcatttg tagatagctt gccttattta tatccttagt atttatcaat
     7861 tccacttcgc ctattacttt tttatcttta catatcttta tttttcctaa aacagttccc
     7921 tttttaattg gcatcttagg attttttact atttcaattt tcttctcaaa ttctttagaa
     7981 cttccttttt taataagagc atttaaatct tctttagcaa ccaatttaac tttgttttca
     8041 tcagccttat ccaatgtaag tgttgctata ttatcacctt tactacataa cttaacactt
     8101 tcataattag caaatccata gtttaaaagg ctagaggcat cattaaatct ttctggagaa
     8161 gtctctgctc ctaaagttgc agcaactaga tgagtattac ctctctttgc agatgctgat
     8221 aaacagtatt ttgcttcttg agtaaaacca gttttaacac cagttgatcc ttgataatgc
     8281 tttataagtt tattagtatt tgcaagacct actgtaactt gtttcttccc tactacaacc
     8341 ttatccatcc atgtagttaa gtatttactt atcatttcgt gttttaatag ttctctagac
     8401 attaaagcta tatcatgagc agatgtatag tggtttgcaa ctggaagtcc atttgtattt
     8461 gcaaaatgag tatcattcat atttaactct tttgctttag cattcattct atcaacaaat
     8521 ccttcaacac ttccagctaa gtgttcagcc atagcaacac aagcatcatt tgcagaagca
     8581 acagctatac cttttaataa tgtatcaacc ttttgagttt ctcctggctc taggaatatt
     8641 tgactaccac ccatactaga tgcagtttca cttacttgaa cttcatcatc aagcttaatc
     8701 ttgcctgaat ccaaagcttc tactataagt agcatagtca ttaccttagt tacactagca
     8761 ggaggaagct ttttatgagc atccttttca tataaaattt gtccactacc aacatccatc
     8821 aaaattgctg attttgaaga tatatttagt tggttggcat cagcattttc cttattattt
     8881 gcaaaagaaa agcttaaagg agtaagcgca attaatatag ccaaagcagt actagctaat
     8941 tttttcatcg atgtcacctc ttaaagttta tttaaactta ttttctcaca tttaactttt
     9001 tttattctaa atgcctagat ataccttgac ctaaattttt tttcttttca agctttttaa
     9061 agtaaccttc taaaacacct ttattagacg cattttctat tatttcaaaa gcatcttcat
     9121 aattcattcc atactctcct gctatttcca tttttgtttg ttttaaagct tttatagcat
     9181 tttgtcttga aacatcatcc ataaaaatcc tcctatcagt aaaatttata tataagtagt
     9241 ttttactaat aaaagattgt tataattggt attttatgta atatatatat tttttaaaat
     9301 gagtattaaa aagacctctt gtaattctta agataatatc aattggattt ttgatattac
     9361 tttaaaaatt acaagaggtc taattttcaa atttatagtt tttttatatt atacttccat
     9421 tatgatagga agtatcattg gatttcgttt agttttttga tataaatatt cttttaggtt
     9481 ttctttaata ttattcttta aataagccca ttctttaata tttttctctt cacattcatt
     9541 tagaacattc ttaattatat cctttgctcc atccattaaa tcttctgact ctcttacata
     9601 tacgaatcct ctggaaatta tatctggacc tgctaagacc ttaccctcat ccttggaaat
     9661 agtaactaca actatcataa gaccatcttc tgataaatgc tttctatccc ttaaaactat
     9721 attacctaca tcgcctactc ctagaccatc aactaatatg tttcctgttt gtatacggtt
     9781 tgctacctta gcagaatttt tatctaattc taaaacatct cctgtttgca tgacaaaaat
     9841 attttcttta tccataccaa gctgttcagc tatttcagca tgtcttttta acattctata
     9901 ttcaccatga gctggcataa aaaactttgg tctaactaat gcatgtataa gttttaattc
     9961 ttcttgacag gcatgtccag aaacgtgtat atcagctata tcactgtata ctacttctgc
    10021 tcctttttca aataagaaat tgattactct tgatattaat ttttcatttc ctggtattgg
    10081 atgagcagat attataacta aatcgccact ctttatttct acttttttgt gctctgaaaa
    10141 agccattcta gcaagagctg acataggttc accttgtgaa ccagttgtta ttatcactaa
    10201 ttcactatct tcatacttac atatatcatt taaatctata agcatgtcat cagaaatatc
    10261 taggtatcct aattcttttg caactccaac tacattgacc attgagcgac ctgatatagc
    10321 aacttttcta ttaaactttt cagcagtatt tattatttgt tgtaatctgt gtatgttgga
    10381 tgcaaaggta gcaactataa ttcttctgcc atttcctttt gcaaataatt cgtcaagacc
    10441 taccccaaca gtcttttcag acatagtaaa tcctggtttt tctgcattag tactatctgc
    10501 cagcattaaa agaactcctt ttttgctcaa ctcacagatt ctatgcatat ccataacatc
    10561 tccatcaata ggagtcaagt caatcttaaa atctcctgtg tggtatatta taccttggtc
    10621 tgtgtgtatt gcaatagagt aagcatctgg tatactatgg ttatttttca aaaactctac
    10681 ttccatatta tcaagcttta taacttgtct aggacctata acatttaact taacattatt
    10741 cattttatgt tctttaagtt ttacttgtat aagacctata ctaagtcttg ccccatatac
    10801 aggtacattt attttcttta atatatatgg aagagctcct atatggtctt catgtccatg
    10861 tgtaataaat atacccttta ttttatccct attttttact aaataagtta tatctggtat
    10921 aactatatct actcctaaca tttcatcctc tggaaaacta agtccagcat ctataacaat
    10981 tatttcatct ttatactcaa caacagtcat attttttcca acttcgttaa gtccacccaa
    11041 ggccattacc tttatcttgt tggtgttctt tttgaacaat tgcatcatct ccttctgtct
    11101 atttaatttt ttaacacgtt ctacaatcat aaataatatc aaatcacgca ctcgctacca
    11161 gttattctta ttgtaccata attcgtatca tattttaagc tatatttaaa atacatttaa
    11221 cgtattattt tgacaaacct attttatttt gatatcctct aaatattata tgatttaata
    11281 tcggataatt taggaggatt tatgcgtggt aaaactcatt gtgcaatagg aatcttaaca
    11341 gctatccaaa catctttaat atttaaaatt cctatatctt tagttgatat tttagtttca
    11401 gctacttttg ctgtactacc cgatttggat aaatctaatt ctatggtctc aaatttcatt
    11461 ctaaaaaaca atgtatccaa atacatatat agaattttta tatatgctgt taatattatt
    11521 attttcttta tttcaataaa tataaatgat aatttttatt taagcgcaat aattacattt
    11581 gttgcaatta taattattga agcaaaacta acccacacat ttctaagaaa agtttttcta
    11641 tcattaatat ttatactatt agctatatgc ttatacatca tagaagttga aatatatttt
    11701 acaatttttt gtctaatgtt gtcaattttt ccctggttaa agcacagaag tttttctcat
    11761 agcatatttg caactataat agtatatttt ttactaaaac agatagaatt aatcactaat
    11821 attaataatt tatcttttta tggtacgatt ggttatgcaa gtcatatgtt tttaggagat
    11881 ttatttacaa agcaaggaat accaattttt tatccgctaa gcgaaaagaa aatttcttta
    11941 ggttttttaa ctgttggagg accatttagt aatttcatag aaaaatcatt catttttgta
    12001 cttataggat taattatatt ttcaatatta aaactataag catcttgaaa actgtatatt
    12061 tgcattttat agatggttta taataaaaaa tggaagaata gcatagaata taaaagttct
    12121 atactattct tccatcgaca ttaagcaata gaagtttatt cttctgaatc gcttactcca
    12181 ttacactcgt cacatagtcc ataaaattta acatcatgat caagtatttt aaatttgtac
    12241 aatgattgta tctctttttc tatattgtct aaaaggtctt ctttagcttc cattatcttt
    12301 ccacaatttt tacaaataag atgatgatga ttatgacagt cttctttatg tagactaatc
    12361 tcatatctta tacatccatc gtctaagttt agttttgata ttaatcctat ttcatccaat
    12421 agctgcattg ttctatatac agtagctaag cctatttcag gacagtcaac cctaactaaa
    12481 tcatagattt cctcactact tagatgtgaa tggtcatgtt taagcaatat ttcaactatt
    12541 gctcttcttt gtggcgtaat cttaaaacca gtttctttta acttgtcttt taataaatcc
    12601 attgtatttg ccataacatc acccttacta ttttcaattg ataatcttta ttaaataata
    12661 ttgtaattga taattcattt tttgtcaaga catttaaata aatttaattt attctcataa
    12721 tataaatata tacccataaa agatatatta ttcaccaaaa ttcataaatt ttttggtatt
    12781 tttaataaaa aacaaaaaaa cagatatata ctataaatgc ttttacaatt aataaggttt
    12841 aattaaagca aatataataa atatctgatt tttatataca aacttaatta cttatctagt
    12901 taagtccatt tgattcatct tcgtcgtaat ttaaaccttc ttcttccatt atagcagtat
    12961 acacagctac aacagtttca tactcttcat cactttccaa aggtattaag atttcacctt
    13021 cttcatcctc atcaattcta aagattaaag cttcttcagc ttcttcatca tctaaaggca
    13081 ttaatattgc atactctttt ccttctgctt ctaatgttaa tattatttca aattggcttt
    13141 caacgccatt ttcgtctatt aaatttatta tattttcttc cataatgtca ttcacctcaa
    13201 atttattttt atttttatta tttatattat atatcataag tattcaattt tatagttctt
    13261 ttatgaattt attttaaaat ctaaatatcc ttgcaaaatt attactgctg ccaacatatc
    13321 tataaccttt tttctttttt gtctactaac atctgcttct aataaagacc tctctgccgc
    13381 tactgtagaa agcctctcat cccaaaactc tacatcaata cctgtttctg cttttaccaa
    13441 ttcacaaaac ttgattactt tttctccttg tggacctaaa gttccattca tattttttgg
    13501 taatcctgat acaattttat ttacttgttt ttcttttatt attgctttta gctcttcaat
    13561 atcttttttc ttgccaactc tttttattgt ttttacacct tgtgcagtta atcccatcaa
    13621 atcactcaca gcaactccaa tagttttatc accaacatca agacccatta ttcttccatc
    13681 taacatagtt cctcctttat ctatttatat tctatagatt aaatacatat tctgaacctc
    13741 tcataactaa ggtcacaggc ttactgcttc atataatttt acataatcaa tcataaaaat
    13801 tgcaatatga ttttttatgt aagcatccag tttacattaa taatcatatt gcatttttta
    13861 tttaaatcct atatgaacag taaaaatttt tttagttatt tttttcaaat attatcatat
    13921 ttatacttat tattattagt ggtataagta tatatataga tgctgtagat gcagcaacta
    13981 ttccagaatc attaactaaa agtgtaatta tgcaaccaac catagatgca ataaaccctt
    14041 taaacaagat tggaaaatta ttcattatct ttctaaagtg tctagatggt ttaaatataa
    14101 gcactgcaat tactccaatt cctacaagta aaatatttac ccatacactt gtctgtgcta
    14161 gttgcatatt catttgaatt tttcttccaa atgtttgtaa tatttctcct ggtccattta
    14221 ggaaaattct ctgtacaaac atacctaaat gagattcact acctgaaagt atatctaaag
    14281 ctgcaaatgc aaaaacgaca actacagctg aaacagctaa taatacagct ttcttaaaat
    14341 ctattttaat gtcatatata agcattataa acaacaaata tgctacacat tctgatatag
    14401 ctccaccaac atttgcaccc attgaaggat atgcactagt tataagtatt attaatgaaa
    14461 aaattacaac aagtaattta gataccttct tataatgtaa taatactgct aagccaaata
    14521 ctgcacttgc tatagttaca ccttcatatt catttcctac accatagtac ctagctccta
    14581 tgacagcatc ataactcatt atgttatttt gcattaagta tgttccaaat acagaatcta
    14641 taactatgac taaaatagta agtgttgcaa aaaatcccat gtgctttata tcattgtcct
    14701 taaataattt tctacctaac aagtataata ttagcgtagt cgcaaatatt cccaaagata
    14761 ttgaaattgg agttttaaaa ttcatcaaag gagctaacat aaatgatagt ggcattatta
    14821 tgcctaattt tataaactcc ttaagtactt tgaatacacg ctctttatgt ggcatataat
    14881 ttctaaagaa aatcgcaaac atggcaatta cccaagaagc agatattacg cctacaaagc
    14941 catttataat agttgacctt attgaagata tagacactat cctttcataa agtgatttta
    15001 gatagctaat attgtcctct ttatttacta aagtataact tctacctacc atctctttat
    15061 tttcaagacc aaatgtacct agtatatcta ctccaacatc taaattggca acaattccag
    15121 cctttcttgt tgtggcagat tccagtagac ctttcccttc tccactaaat tttattattg
    15181 gagaaagtct tctcttattc ttataatcta ggtcacttgg aaatgcactt gctatataaa
    15241 cagtgtcatt ttctccaacc atagaaaata cttgttcaag atatttattt atatttttta
    15301 caatattttt cttcattgta tcataagtat tatcatttag atttaatcta tacatatcta
    15361 atctatatgt atctccaagt tctacaaata tagcatcact atttttatag gattttttag
    15421 tttcatctag taatttatca taatctgtag atattccaaa tggcatttta gaatctttct
    15481 tattaatatt atcaatatta cctgaatcaa tccttccata ttggtccata gctactaaac
    15541 ataagtttct gtttttaact aattgattat tttcaattat atcagcattt ccaattacag
    15601 atgtctttaa accattttct gataaagttt ttcctaatga ccctaaattt gctccatatt
    15661 ctccatactc aagattttca tttatagatc tattaatgcc taaatcattt atttctttag
    15721 ctttttgacc tgttgcgact tcaaaagctt tagcagtatc ttggtctact ttttgaaaat
    15781 tgatatagtc ttcagtagtt acactagctc ttgttcctgc acccatactt gcataagacc
    15841 ttctatcatc agtaccttga tcccctctta tattcatgag agctacatag cctctctttt
    15901 ctatctcatt tttcaagatt ggaatattca tcatacttcc aagattggtc ctattcatat
    15961 caataaatat gaccttgcct ttttcttcag caaaaccata gctagcagtt gatacaaaaa
    16021 tcataatgac tattgcaaac aacgacataa tcttttttct catttatttg acctactttc
    16081 tattcagata gtgcgtgatt acttcttcaa gtatctcatc tctttcaaat tttttaatta
    16141 tagctcttgc atttttatga ctagttatat agctagaatc accagaaagg agatacccta
    16201 taatttgatt tatagggtta tatccttttt caactaatgc tttatataca aaatcaatag
    16261 tatctcctac actcatccta tcttctggta ttccttcaaa tttcatagtg tagtctaaat
    16321 ctttttccaa actaaaaacc tccttgagtg aatgttattt aacttgtgtc ttaataacct
    16381 cacttgcata gcttaaagct tggtcaacct tagatacatc actagctcct gcttgtgcca
    16441 tattaggtct tcctccacct tttcctccag ctatttttgc aacttctcta acaatattac
    16501 ctgaatgtat tcccttatct aatacatctt tagtggcagt aactacaaag ttaactttat
    16561 catctactac atttgcaagt actactacac cagaaccaag cttatctctt agattatctg
    16621 ctgtttctct tagtgtatcc atatccatac cttcaaattt attagttatc aaattaactc
    16681 catttacttc aactttagaa tcaaaaatag aatcaactga ttgtaaactc atcttagctt
    16741 tcatatcatg caattcttta gataagtttt tattttcttc taataaagaa cttattcttt
    16801 gaattaaatt atcttcttta gattttaagt ttacacaaac ttcagagata attccatctc
    16861 tttcttttag gtattcataa acagcttttc ctgttattgc ttctattctt cttacacctg
    16921 ctgctactcc accttcagat aatattttga acattcctac ttgagaagta tttgtcaagt
    16981 gagttcctcc acaaagttct gtagaataat ctcccataga aactactctt acctcatcac
    17041 catatttttc accaaatagt gctgtagctc ctttttcttt agcttccttt atattcataa
    17101 tatcacattt tatgtctaaa gatgataaaa taacattatt tactttttct tctattactt
    17161 ttaattcttc atttgatatc gcttcaaagt gagtaatatc aaatctaagt ctttctggag
    17221 ttactaaaga accagcttga ttaacatgtt ctcctaatac ttctcttaat gccttatgaa
    17281 gtaaatgtgt agcactgtga tttcttgcag ctgacattct agtttctcta tctacgagtg
    17341 tctttacttt atccccatta cttattcttc ctgattttat tatacctata tgttttatac
    17401 tattattagc acctttttta gtatttaata cttctaaaac taagttttca ttagttatca
    17461 atccacaatc tccaacttgt cctccacctt caggatagaa agtagtgtta tctagtacta
    17521 tagatacctt atcgccttct tctgcacttt gaactagctc atcatcttta actatagctt
    17581 caatagttcc ttcaccataa atttcactat acccattaaa tgtactgtca actgtagatt
    17641 ctaattttga tagagggtct tccttccaac tttctccatc catatttcct ctagcatttc
    17701 tagctctttc tttttgcttt tccatttctt cattaaaagc ttcttcatct acagatagat
    17761 gttcttcttc taatatttct ttagttaagt ctatagggaa gccataagta tcatatagtt
    17821 taaaagcttc ttgaccactt aggacagtct ttccttcatt ttttaatact tctatataag
    17881 agttcaatat ttctgttcct tggtctatag tttcattgaa tttttcttct tctattccaa
    17941 ctactttttt aatataactt tctttttcaa ctaaaactgg atatgcttta tcatttactt
    18001 ttataacttc atctattagt ttctgtaaaa ataattcttt tactcctaat aacttaccat
    18061 gacgagcagc acgtctaagg agtcttctaa gaacatatcc tcttccttca tttgatggaa
    18121 gcactccatc actaactaag aatgttacag ctcttatgtg gtcagttatt attcttattg
    18181 atatatcatt ttttggattc tctccatatt ttactcctgt taacttctca actgcttcta
    18241 gtatagattt aattgtatca acttcaaaga tagtgtctac gccttgcata atacatccca
    18301 ttctttcaag acccatacct gtatctatat tcttgttttc taatagacta taatttcctt
    18361 cttcatctct atcaaattga gtaaatacat ggttccaaaa ttctaaatac ctatcacaat
    18421 cacagcctgg tttacagtct ggattgtcac atccatattc ttctcctcta tcaaaatata
    18481 tttctgaaca aggaccacaa ggacctgtac ctatttccca gaaattatca tcttttccaa
    18541 gtctaaccat tctttcttct gggaaattca tttcttttgc ccatatatca taagaatcat
    18601 catcttcttc atatacagtc acccatatct tatcttctgg tatatttagc cattctgtaa
    18661 caaattccca tccccatttg attgactctc ttttaaagta atctccaaat gagaagttac
    18721 ccatcatttc aaagaatgta gcatgtcttg cagttatacc tacattttct atatctcctg
    18781 ttcttataca tttttgagat gtacacattc tcacacttgg aggtacttct acacctgaaa
    18841 agtagttttt caaaggtgcc atacctgagt ttataagtaa caaactctta tcattgtttg
    18901 gtactaaaga ataactattt gctacataat gaccttttga ctcaaaaaat tctaaaaact
    18961 tacttcttat ttcatttaat cccatctttt ccatatcatg ttcctcctaa taaattttat
    19021 tttttcgttt aaataaaaaa cctcgtccct ataaataaat ttataggggc gaggacaatc
    19081 gcggtaccac cctaattatc atacaaagta tgatatcttc ggaaaacctt agctataacg
    19141 taactaccgt caatctctac ttaaatcttc tttataaaat ataaattgtt caagattgct
    19201 actaaaaggc tgcttcaaat atcatattct aagggcttcc agcatttccc tctctctgta
    19261 agacatcaaa tattttacta ttccttatca ctgtatttgt tttttaatta atatactaat
    19321 tatattacta aattttacaa aattaatcaa tactatattt tcatatacaa taaatttatt
    19381 ttataaactt tatttactct taatatactt tattgcttat ttttttaatt ttttagatgt
    19441 ttttataaac ttttctcgat tatacctcca cctactacaa tatctccatc atacattact
    19501 acagattgac ctttagtaat agctctttga gcttcatcaa aaactatttt aatagtatct
    19561 tctcctactc tatgaatagt agctggtgat ggttttgctg aatatcttat tttggcttga
    19621 actcttaagg gttcttctaa cgtatctatt gatataaagt taacatcttt agcaataagt
    19681 tcctttttaa ataaatcttc attgtctcca agaactatgg tattatttat tggatttatg
    19741 tctattacaa acattggttt tccaaaagta attccaagcc cttttctttg gcctatagta
    19801 taatataata tacccttatg ttttccaagt atattgcctt tagtatctac aaaaaaacct
    19861 tcttcaatac gctttttaga atgttttttt acataatttg catagtcatt atctttaaca
    19921 aaacaaattt cttgactatc aggcttattg tgtactgcca tacccatttc cttagcaatt
    19981 tctcttactc tatctttttc atagtcacct attggcaata aagtatgctc tagttgctct
    20041 tgtgtaagat tataaagtgc ataagtttgg tcttttttat ctgtaacaga tttttttagc
    20101 aaatatcttc ctgtgctttc atccttttct atctttgcat agtgacctgt agctacataa
    20161 tcacaaccta tttgtctagc ctttttataa aaatcatcaa attttatatg tttattacaa
    20221 gctatacagg gattaggagt ttttccttcc aaatattcat ctataaaata atctattact
    20281 ttttctttaa acacttctct aaaatttaaa acataaaatg gtatacctat tttatttgct
    20341 acccttctag catcttcaac agcagataaa gagcaacaac caccttcaat ttcaacaaca
    20401 tcatcatctt gccacaactt catagtaaca ccaatgacat catatccttg ttgttttaaa
    20461 agatatgcag ctacagagct atcaactcct ccactcatac ctatcattac ttttttattc
    20521 ataaacaaat ttcacctcat cttttgcatt acttattatt ataccatata gagcaagtat
    20581 tgtacttatt taaaatatag cttgttctat tttctaaaaa aataatcatc tttattattt
    20641 gaatcttatg gattattttg ttaactaatt aacctctaaa tcaagttaaa atacttaatt
    20701 taggcaataa aaaatagcca ttttaaaaac agctattttt tatgtcctaa ttatatcatt
    20761 agtacttctt tttaatcatt gtaaacttct cataacacaa tcacttattt ttattcttct
    20821 tcttcaacat catggtcatg agcatcatct ataacatatc catccaattc tggtatatgg
    20881 atattgttct tttgagcata atctataaga gctgctttta cagcttgttc agctaaaact
    20941 gaacaatgca tctttactgg tggtaaacca tccaaagctt ctgcaacagc tttatttgta
    21001 agttctaatg catcttttat agtttttcct tttatcattt cagttgccat agaagaactt
    21061 gctatagctg aaccacagcc aaatgtttta aacttaacat cctttattac atctccatct
    21121 atgtctaaaa atatcttcat tatatctcca catgtagggt ttccaacttc acctacacca
    21181 cttgcattat caatttctcc catatttctt ggattcataa aatgttccat aactttatca
    21241 ctatattgca ttatcttttc ctcctactca atttatgtct attttttatg ctttatcttt
    21301 atgtctattt tactaaacct tgtttcttcg catcatcata aagtggtgac atgcttctaa
    21361 gtctttctat tacttttggt aagttctcta gtatataatc tatatcatca tctgttgtaa
    21421 aatctccaac tgtaagtctt aatgaaccat gtgctatttc atgtggtaaa cctattgcaa
    21481 gaagtacatg tgaagggtct aatgaaccag aagtacatgc agaaccactt gaaccagcaa
    21541 ttcctaacat atctaataat aaaagtattc cttcaccttc tataaattgg aatgcaaagt
    21601 ttgcatttcc tggcaatcta ttttctaagc taccatttac tcttgtgtaa ggtattcttt
    21661 ctaacacacc atctattaac ttatttctaa gacgagttaa agtttctaca tgattttgca
    21721 tattttcctt agctaattct gctgcttttc catatccaac tattgcaggt atattttctg
    21781 taccagctct tttgcttttt tcttgtgctc caccatggac aaagttatga agtcttacac
    21841 cttttcttat gtataaagct cctacacctt ttggtccata tattttatgt gaagacatac
    21901 tcatcaaatc tattcctaat tctttaacat ctactggaat attacctgta gcttgtactg
    21961 catcagtgtg gaataatatc ttatgttttt tagctatttc ggatatttct ttaataggct
    22021 gtatagttcc tatttcatta tttgcaaaca ttatacttat aagtatagta gtatctttta
    22081 ttgaatcttc tagttgcttt aagtctactt ttccttcgct atcaacatct aaataagtta
    22141 tttcaaatcc atgatgtttt gctaagtatt cacatgtatg aagtattgca tggtgttcta
    22201 tttttgaagt tattatatga ttacctttgt ttttattagc ataagctacg ccctctagtg
    22261 tccagttatc actttctgaa ccacctgctg taaaatatat ttcactaggt tcagcattta
    22321 taagggctgc tacttgttct cttgctttat ccaaagcatc ttttgcttct cttccgaatg
    22381 tgtgaaaact agatgcatta ccaaaataat ctgttaggta tggcatcatt gcatccaata
    22441 cttctttttt aataggtgtt gttgcagaat aatccatata caatcttctt ttttccatta
    22501 cattcatctc caaatctatt ttttaatatt tgttatatca ttttctaatt tatttttgtt
    22561 atagtcattt atcatatctt taagagtaat tgaatctata acatcttcta tacccttttt
    22621 catcttttcc caaactattt ttgttacaca catgtttgag ttttcacata catcttcatc
    22681 tagtacacag tcagataatg caactggtcc ttctaatact acaagtatat ctcctactgt
    22741 tatgtcttca gcattctttg aaagcaaata acctccttga gcacctctca cactttttac
    22801 tagacccgat ttttttaaag atgaaaatat ttgttctaag tactgatctg atattttttg
    22861 cttcttagca ataaatttta atgatactgg tccattgtct tgatttaatg ctaattcaaa
    22921 cattgctttt agtccatatc tacctttagt agacaacttc atatattatc acctctatat
    22981 agaaatctaa ttcatactgt tttagtagga attactttca agataatttt attataccct
    23041 actaattttg tcaagattaa ttttaatttt ttattttgaa taaattcccc attttccaat
    23101 gttttcaaat cctagttttt tatatatctt tccagcctct tcattatcat aaaacaaaca
    23161 aggaattttg ttttctctca gtaactctga acatagttta attaggcatt ttgtagcaag
    23221 tcctttagct ctatatttag gatgtgttcc tactccaatt atcattgcat gagtcctatt
    23281 ttctgaagta ctctttgcca ttgacaccac ctgtttgtta atctctatac aatatcctct
    23341 acctgtcctt agtccatttt ttaaattctc taaagttgta ctgtgaaatt catctattaa
    23401 gtcataaagt ttcactgtct tttttagatt tccaagccta attctcttaa cctttgcatt
    23461 acaattatta tctatcaaaa actttttagt ttgaagtttg caaaaatcaa ctacctttaa
    23521 attattaagt cctaatctct ttgctaaagc atctacagca catattttcc cagatatttc
    23581 ttcgtaatta gtattacgaa gtagattata aaaaccttca acatcatact ctccatcaga
    23641 ataaaacatc ataaattcaa aatatttaag taatattgcc tttatttcac catgttcacc
    23701 cacatctgcc catatattta aaaaattatt tccatatcca tatctttcaa tatcccctat
    23761 tataaacaaa ttgtactcag gttctttttt taagtatttc ataactctac tgtgataagt
    23821 tgagttaagt tttataatca taatatctac ccccgataca taaagttcag tctaaaaatc
    23881 actatttaga tattctaaat atttttttat atttttctca gttttatttt cttgtggtat
    23941 gtaataaata ctatctttta tgctatctgg taaatactgt tgctttacat aatgattttt
    24001 aaaattatga ggatatttgt atccacaacc cctacctatt tctttagaac cagaatagtg
    24061 agcatccttt atactatttg gtatatcctt aacaaactct ttatccagtt catccatagc
    24121 tttcattatt gctatacatg cagaattaga ctttggagat gtagccaaaa gaatagtagc
    24181 ttctgctaat ggtattttcg cttctggaaa tccaagttgc atagctgagt ctacacatgc
    24241 ctttacaatt acaatagcat ttggataagc taaacctata tcttcactag ctattactaa
    24301 aagtctccta catatactta tcaaatcccc accttttata agtcttgcta gatagtgtat
    24361 agatgcctgt gggtcacttc ctcttataga tttttgaaat gcacttaaaa tatcataatg
    24421 actatcacca tttttgtcat agtttataat tttattaaat gtagatgccc ttattacatc
    24481 tgaatctata taagttatat tatccttatt tggtttagtt gaatagacta ccacttccaa
    24541 aatatttaag gctcttctca tatctccatc agaaagaatt gctatatctt caatagcatc
    24601 attattacac tcaatatcca tatagctatc ttcatttaat acttcaacag ctcttttcag
    24661 tcctttttct atatcaagtt tttctaaagg tttaaattca aatacagtag acctacttaa
    24721 aagagcttta tatacataat gatatggatt ttctgtagtg ctagcaatca aagttatact
    24781 cccattttcc ataaattcta atattgattg ttgctgtttt ttattaaaac tttgtatttc
    24841 atctatatat aataggactc catttacatt atttatactt ccaagctctg atatcacctt
    24901 ttttatatct tctaaagatg aattagtagc atttatttta tagaagcttt tattgcttct
    24961 ttctgctatt atttccgcta ctgtagtttt accaacacca ggaggaccaa aaaatatcat
    25021 atttggtaaa aaattagatt gtaatatctt agacaatatt tttccattac ctattatatg
    25081 actttgacct attacatcat tcattgtttt tggtcttatt ttatctgcta aaggcatttt
    25141 ctcactcctt tttaatatac ttatcattac cttaataatt cgtctaaaaa aggtatctat
    25201 ttgaaataga taccttttct aatctaaacc tataaaatat agattattga ttgtttttta
    25261 atttttttaa ttcatctgta agtttgtcat taagtattct tatatgagta cctttcatac
    25321 ctaatgatct tgattctatc acacctgcac tctcaaattt tctaagtgca tttactatta
    25381 cagacctagt tataccaact ctatcagcta tcttacttgc tacaagtaga ccttcttttc
    25441 catccaattc agcaaaaata tgttcaactg cttcaagctc ggagtaggat agagtgccta
    25501 ttgccatttg aactacagct ttctttctca tttcttcttc taattcttca cctattgctc
    25561 ttaatatttc aagaccaaca acagttgcac tgtattcagc tattactaaa tcatcatcat
    25621 tgaatgaatt tgaatatctt gaaagtacca atgttcctaa tctttgaccg cttcctaata
    25681 ttggaactac tgtagtatat ttttgtaatc ttccatgttc ttcaggaaag atttctaata
    25741 tcttctcacc atttaaattt tctaatgttt catcaatttt taacacattt tgagtatatt
    25801 catctgaaaa tttcttttgc ttagtatact catcttctat aactgaactg tcttgaacat
    25861 catttaaatg aagacctagt actttacctt ttgcacttac tacataaaca ttagaactta
    25921 aaacgtcgcc caatgctccg gccagtaaat caaaagagac actgcttcca ccacttgttt
    25981 gtaatgtttt atttattttc cttgtttttt gtaacacttc acttgccatt taatcatctc
    26041 ctcatgaaat ttaggccttt taataacctt ttatattttc taatattatt ttcacattta
    26101 atgaaaattt atttttctat tagttgttta cacttgaaag attatcatag attggaacct
    26161 ttttcaagag aattatgtga tttttttcaa ttttcactct tttccgtcat tatgctcttt
    26221 tgtctcttta ttacattctt tattagaaca cactgttttt gtttcagatt tagtcacttt
    26281 ttcaaccata tatgaaccac acttctcaca aaactctcct gttggcttat tccaagctac
    26341 aaagtcacag tttggataat tagaacaccc ataaaaagct ttacctcttt tagattttct
    26401 aagtataata tctccttctt cacattttgg acatttaaca ccaattttat tcataattgg
    26461 tctagttgtt ttacaatcgg gatagttttt acaagccata aactttccaa atctaccata
    26521 tttgataacc atattagacc cacagttctc gcaaatctca tcagtttctt catccatatt
    26581 tactttttct atattttcaa gagcttcttc aatagcctct ttaagtggtg catatgattc
    26641 tgatacaatc tttttccaat ctgtattgcc ttcttctata acatcaagtt tactttccat
    26701 atcagcagta aaatctacat ctataaattt atggaaatta ttttccaaaa tatcagtaac
    26761 tattattcca agttctgttg gacatagact tgttccttgc ttttcaacat actctctatt
    26821 cagtatagta gctattgttg gagcatacgt acttggtcta cctataccta gttcttctag
    26881 tgtttttact aaactagctt ctgtatatct tgctggtggt tgtgtaaaat gttggtctgg
    26941 caatatattt tctatattta atatatctcc tttttctata cttggtaaaa ttttgtcttc
    27001 tctttctgaa aaattatata ccttggtata accatcaaat ttcatttttg aaccagttgc
    27061 cttaaataca atatcgccta ttttacattc tacatttagt atatcaaaca ctgaatcttc
    27121 catttgacta gctacaaatc ttctccaaat taaattgtat aacttgtact ggtctttgct
    27181 caatgaggct tttatactct caggagttct atcaactgag gttggtctta ttgcctcatg
    27241 ggcatcttga acctttttag tatccttttt ttctttttta tcaccagtgt ttttatagta
    27301 gttttctcct aaattgttta cgatatagcc cttagctttt tcttttgctt catcagatat
    27361 tcttttagag tcagttctta tatatgatat aagaccaaca gtaccttcac cttctatgtc
    27421 gataccttca tataattctt gtgctatcat cattgttttt ttagtagtaa aaaataactt
    27481 atttgctcct tcttgttgaa gcatacttgt tgtaaatggt tttggagctg atttacgtct
    27541 tgatttagat tctatcttct caacctttaa atctttacct tccatttctt ttagtatttc
    27601 atttacagct tcttcatttt ctaattcaat cttttcatca tttttaccat aaaatttcaa
    27661 agttatatct ttgtctttta ctgtcttagc ctcaacatct attgtccagt attcttttgg
    27721 aataaatgcc tttatttctt tttctctgtc acaaattaac tttgttgtaa cagattgcac
    27781 tctacctgca ctaagacctt ttctaacctt ttgccataat ataggactta tttgataacc
    27841 taaaagtctg tctagcactc ttcttgcctg ttgtgcatca accaaattta tatcaatatt
    27901 tctaggatgt ttaattgctt ttttaattgc atccttagtt atctcattaa actctattct
    27961 acaatcctca gattcatcta aatttagtat atgagctaaa tgccatgata tagcttcacc
    28021 ttctctatca gggtcagttg ctagatatac ttgtttagat tttttagctt ctttttttaa
    28081 ttcttttatt acatcgcctt ttcctcttat atttatatat tgaggttcaa aattattttc
    28141 tatatctaca cctaatttac ttttaggtaa atctctgaca tgaccaactg atgctttaac
    28201 tgtgtaatga cttttcccta aaaatttttc tatagtttta gcttttgcag gcgattctac
    28261 gatgactaat gttttggcca taaaaccata cacccccact acctaatctt aatttataca
    28321 tttaaactgt acgttttatt attcatttct actactaact catttagtac taattcattg
    28381 attattgaat ttacatactt tatttctata ccagtataat cacaaatact atctatatgc
    28441 aagtttcctt ctctttttat agcttcaatt atttgcttag acttggcatt tagacttata
    28501 ttatcatatt tttgatttat ttttttatca ataatattaa atatgttata ttcatttaaa
    28561 atatcatcta tattttcaat taattttgca ccttctttta taattttatg acaacctcta
    28621 ctcatttgag aatttatatt accaggtatt gcaaaaacat tttttccatg ttcaagagca
    28681 aaatctactg tgattagtgc accacttttt attgctgctt ctacaacaac tactccatca
    28741 cttaaaccac tgataattct atttctatta gaaaaatggt acggggctac tgtcgagtta
    28801 atattatact ctgataataa taatccccca ttttctaata ttttatttga taaatgtaaa
    28861 ttttgttttg gaagaggatt gtctactcct gaaccaagta ctgctatagt tttagatttt
    28921 ccactcatac aacctatgtg cgagtatgca tctattccta tagctaatcc acttactata
    28981 ttaactccat attgggatag ttgacaactt attgtttttg cacaattaat tccataggct
    29041 gtaggttttc ttgaacctac tatagctata ttaaaattat tattaactaa acctatgtca
    29101 cctttgtaga ataataactt tggagcgttg tatatattct ttaaattttc aggatattct
    29161 ttatcatatt tacaaatata tttaatcgct tttttgtaaa gtagttcttt tatattttct
    29221 aaataagcgt gacctctata ttttactata ttttttctaa tattcaagct tatatttttt
    29281 aaattatata tttctttttc agaaaaatca aatatatctt caatatttac tatttcattt
    29341 tctattattt caattgtttt tgttgttatt ccaccaattg attttaacca taaataagta
    29401 tctctttttt ccataaaatc cacctcaaaa aactatttaa aataactata ataagccttt
    29461 ctaaatgaaa aagcttctat aatacactgt gaatttatca agtctctttc ttctaaatct
    29521 gctattgttc ttgccatttt taaaagtttt gtataacttc tactgcttag gttgtattta
    29581 ttaaatatca tctcagccgt ttttgaagct tctttttcca gtttacaata tttaaataaa
    29641 ttgtaagctt taatttcact attatttttt atattatcct tcttaaatct atttatctgt
    29701 atttttctag cattttctac tcttctcttt attttttgag agctttcttc ttgttttaaa
    29761 gaattaaaat ctgaatattt tatagaatta acttctacaa aaatatcaaa cctatctaac
    29821 aatggacctg atattttatt tatgtatcta tcaatttcgt tacttctaca tctacactct
    29881 gtctctgaca tataataacc acatggacat ggattcatag ctgcaactaa cagtactcta
    29941 caaggatatt ttgcactgta ctttactctg gatatattta catatccatc ttctataggt
    30001 tgtcttaaag tctcaagtat ttttctatca aattcggcta tctcatctaa aaataagata
    30061 cctctatgtg ctaaagcaat ttctccaggt cttgcatcca ttcctcctcc aattaaagat
    30121 tgctttgtag ttgtatgatg aggtgctcta aaaggtcttt tatcaattat tcctttagtt
    30181 tcatttatca tacccaatat actatagacc ttacttactt ctatcatttc ttctacactt
    30241 atatctggta aaattgtcct tactcttttt gcaatcatag tttttcctga gcctggaggt
    30301 ccaatcataa acatattatg atttccagca gctgcaattt ctgcactcct ctttacaaaa
    30361 taatttcctt ttacatcttt aaagtcttca tcatatttac tttcttcatt attaatctta
    30421 gtatatttgc aatctatata actattatct ttttctaatt cttcgttctc ttttcttgac
    30481 ttatcatcca aaaaagacat tatccttact ttatcgactt ttatctcttc gtttaaaaaa
    30541 tcgacacatt cttttaaact tttaatagga attatatcaa tttcatctac aaatagactt
    30601 tcttttatgt tctcaattgg tataaaaata cgttttatgt tctgagtttt tgcacccata
    30661 attatgggca atatacctct tacttttctt attttcccat ctaatgataa ttctcctata
    30721 aacatacttt ctcttatgta attttcatct ttttttatta actctcttaa aaggcctata
    30781 cttatagata aatctaaaaa agctccttct ttttttatat ctgctggtga taaatttaca
    30841 actattctcg tgcttggaaa tttatatcca ctattaagaa ttgctgactt tactctttct
    30901 cttgcttctt taatttcttt gcctggaaga ccaacaatat taaaactagg tattccattg
    30961 cttacatcta cttcaacctt aactaaaaag ctgtcgattc ctactaagtt gcttgaatta
    31021 ataatactta acatatttaa tcctttccaa aaacattatc ttttttaaaa agcattcatt
    31081 atgtgattta ttcttttttc taataaatat acctctataa catcaaatct tatgggagtg
    31141 ttatttaagt tattttttat aatataataa cttgcaactc caattatctt ttttcttttt
    31201 ttgaagctta cagattcaca agggtagcca aactttatgt tagaccttga tttcacctcc
    31261 acaaatataa tttcatcttc catttttgct attatatcta tttcccctat ctttaatctg
    31321 taattttttt ctagtatctt tgctcctttt gatagcaaat aattaactgc tactttttct
    31381 ccaaaatcac ctttttcttt attattcatt attcactcca atacattaaa ttttcacttt
    31441 taaattatgg tcagtataca attttactat tcaagttttt ggattgattt tatttccatc
    31501 aatattaata aatacttcta ttgactttat tcttttatga tattattcta gttttcatag
    31561 gaaaagttta tttttttgga ggagtgcctt taatgaacag agaaaaatta gttgctttta
    31621 tacgatattt atctttattt atattagttg taagctattt gaaaaatgtt gaaaatacat
    31681 tgtatccggt cataactatg ataatattat ttctaattat aataaataat caagttagat
    31741 ttttttcttt atcaaatgag aataaattta tacttatttc ttacttttta gaacttatat
    31801 taatttttat actttgtaat tatacaaaaa cttttaattc gatttacttt gttcctttaa
    31861 tattagatat atcattttta ataaaggaaa aatataagta catattgttc tcttttgtta
    31921 taatatcttc tcttattatt agtttagata aaaatatata tttggcactg gagtcaagct
    31981 ctatattgct aattataact gtactttcta tatatataga aaatgagaat ttatcaaaat
    32041 tatacagtca aaatctttat gataagctta gaatttctaa agatgaatta aaaaaagtta
    32101 atgctgattt ggaaacttat gcaagttcta tagaagaatt agcaatttta aaagaaagaa
    32161 atcgaatatc aagagaaata catgatagtg taggacattc tctttctaca acaataatac
    32221 aattaaatgc tatagaaaaa ctcttaaaag acaaacctct aatttatgac ttagtacatg
    32281 aacttagaga atttgtaact gaaagttttc aagatgtaag aagggctata tctgagttaa
    32341 aacctgttga atatgaaaat taccaaagtt tatttaaaat caaagaatta gttaaaagct
    32401 ttattaagct tacaaatatt aatgttaaat taactatttc aaaaaatact tggaacttat
    32461 ccagaaatca atctatagct ttatatagac tcatacagga atccctttcc aactcatcta
    32521 ggcacggaaa ggcaactgaa atcagaattt ttattacatt caatacttca aatcttataa
    32581 ttactattag tgataatggt ataggatgtg gcaatataaa aaaaggaaat ggacttaata
    32641 gtatcaatga gagaatatat gaattaaatg gtaaagttga atttgataat tctaataatg
    32701 gtttcacaat tagagcttct tttcctaaat tttcaggggg tgattttttt gaataaaatt
    32761 aaagttctta tagtagatga cgaaaaatta attagaaaag gtcttaaaat tatattatca
    32821 tcttataatg atttagaaat tgtaggagat gcttctaatg gatatgaagc tttagaattt
    32881 tgtaaaatga atgatgtaga catagttctt atggatatac gaatgaaagt atgtgatggg
    32941 gttctaggta caaggcttat aaaggaatat aataattcta taacattatt aattttaaca
    33001 acttttaatg atgatgaata tataaaagat gctatgaagt ttggtgcttc aggatacctt
    33061 ttaaaagata gctctgatga agtattgcat gaagggattc gttcttcatt ttttggcaat
    33121 attgtgcttg ataaaagtgt agctgaaaaa atcatgacct ctgaaaaaac ggttaaacaa
    33181 gagcatcttt atgacatgta caatttaaca gaaaaagaaa tatctataat tagactaatt
    33241 gcaaatggac ttaataataa agaaataagt caagaactat tcttatctga aggtacaata
    33301 aagaataaca taactaatat tttagctaaa ctagaacttc gtgacagaac tcaactagca
    33361 atctttgctt tcaaaaataa aattgtaata gaataaatct aaaaatataa agtgacttaa
    33421 gtcacttttt ttagtgactt atagtaatag aattataatt cacaattctt tattataata
    33481 ttatagcttt ttaacttata caaaattatt ttggagggat tactatggat atagtcagag
    33541 taaataatat aacaaaaaga tttaatgata aattagtact tgataacatc agcttttctg
    33601 ttaaaaaagg tgagatattc ggacttattg gcccaaatgg tgcaggtaaa tctacactta
    33661 taaatataat tacaaatctt atgttaccaa atagtggtag tattcaaatc aatggtttag
    33721 atttatcaaa agattatata aaagcaaagt ctataatagg gttagttcca caagaattag
    33781 caattataga aactcttact ccttttgata acttagagta ctttggagct ttctacggtt
    33841 taaagggaaa actacttaaa gaaagaatca ttgaagcatt agaagttaca ggtcttactg
    33901 aagtcaaaaa gaaaaaggtc aaaaaattat ctggtggtat gcaaaggaga ttaaatattg
    33961 gaatagcact cttaaatcat cctaaaatat taatattgga tgaaccaact gtaggtgtag
    34021 acccccaatc aagaaatcat attttcaatt ttataaaaga tatatctaaa aaacatgaaa
    34081 ctactgtaat atatacttcc cattatatgg aagaagttga acacctttgt tctaaaattt
    34141 ttattatgga tgaaggtaaa gaaattgctt ttggagataa tgattattta aaatcactag
    34201 tatctacaaa tacaaaatta attctggaaa taaaaaatat aaatgctcaa cttatctttg
    34261 atttaaaaaa tactaaaggt gttatatctg ttttagaaaa taattcatta ttagaattgg
    34321 atatagataa aaaattacaa cttacagata tactctctat aattgacaaa aacgattcaa
    34381 aaataatgaa aatttcttat gaagaaccta gtctagaaga tgtattttta aatctaacag
    34441 gcaaaaattt aagggactaa tggaggtgat tttatgaaat tatacatgag tgtaaaaact
    34501 atgctaaagg gtttaaaaag ctcctttata cttaatttaa tatatttttt agctttgcct
    34561 ctgattttat cttggtttct tgggatggtt acagaaagca tgtttcaaaa ccctataaaa
    34621 acagaatcta cccccattgt tatatatgac aaagataaca caagattatc aaatgatttg
    34681 acaaagtatt tgaaaaatga tttatcttat atattaacag ttaaaaaaga tgattctaag
    34741 gcagaattaa agcttactat acctaaaggc tatgagagta gtttattaaa tgaaaaatca
    34801 aatactctaa acatagaaaa acttggaact cgtgatgata ttgcaatatt gcttcaagat
    34861 atattagata cttaccatga aaaattttat ttaaataatt ctcagaaaat aagttcagaa
    34921 gatttttcta aattatttaa taaaaattct attgatactt ctataataaa taacaatgtt
    34981 aaacagagct cttatgaata ctttgcttta gtttcactag gatttcttgt aataattttt
    35041 ataatgaaca atattttgtc aaattatata agtgaatcaa agggactttc aaaaagactt
    35101 tattctatgc ctataactag agtacaattc ttaatttatg actttgtagg tttatggatt
    35161 tattcattta tattcttatt attatatgtt ttattcttta gaatacttgg aataacattt
    35221 aaaggtaatt ttgccatatt gctcctactt tgtgctttat catcttattt tatgacttca
    35281 atatctacct ttgtaaccag cttttttagt aaaaaatacg gtacagcaat agtttatgca
    35341 ttactctttt tacagacaat ttttggaggt atcttcagta tgataagtga tacatttact
    35401 aagcttacaa gtttatctcc tacctattta ataggagaat tgtttagcaa ttatgaaaca
    35461 tttaaaacca tagattcaat aggaaattta attttcacat gtttaattat ctctacaata
    35521 ttaattgcac ttgctattgt aaaggaaaaa tataaatgga gggaggttta ataatgatta
    35581 gattaactat tgcaaatata aaaagatatc taaaaaatca tactctttta attaatatgg
    35641 ttatgcttcc tattatacta attttttcac ttaatttttt tatcaacaac tcgggaaatc
    35701 aatcaatgta cttttctcca gtagcaattg tatctgactc ttcaggaaag tatgaacata
    35761 agttaataaa tagttctaaa ttaaaagaaa attcatttag attaaatgaa caagataagg
    35821 ctatgaatct attaaaaaat aataaggttt ctgctgtatt cgttttagat aaaaattttt
    35881 caaatagtat agataaatta caacgacctg tagttaaatg ctttaaaatt gaaaatggtg
    35941 gtggtagtct ttgggcagaa tcacaaatag aatcttttat tactaaatcg ttaaaattga
    36001 aagtggataa aaatatagat gataaattga caaagacaaa tataattgat aacaaaccag
    36061 ctaagaataa aggttcattt ttagtagtct tcttgatatg ctattttatg tatattaatg
    36121 cggcacatct tgcttctgat ttatttacat taaaaaaatc aaatgtgcta aaaagactta
    36181 tctctacaga taataaagat ataaaaataa ttttcagtat atttttagga ctatttttta
    36241 ttcaatcaat tgtatacact tttgctctat tatgtttttc aattatagaa gactttaatt
    36301 tgagtctaaa tgtattgatg attgtactag caaatagttt tgtttccact ggatttgtat
    36361 tttgggtagc tagagtattt aaaaatgaaa gttctataag tcttatatct acattttatt
    36421 ctttaatagg tctagctata tctatctcta gtctaatacc atcaatggat aaattatcct
    36481 ttatgactaa tctttcaaag ttcacaccat tttattggac tatagatgct attaaaaaca
    36541 atggtagtat tttaataaat ataatagctc taatattaat tggaattata tttgtaactg
    36601 caggaagtct taaactaaga gattttgcta aaaactaata attattaaat ataattagta
    36661 tctattttta tataattgta aaagaatatt tcaacatatt aaattatttt atcttatatt
    36721 tttctcttta gtttcacaca tcaccaagtc taaactctat attatatatt aatatttttg
    36781 acttgtcaag ttatttatgt tataatatta atcattagat aattaaagca ttgtacctaa
    36841 gttgcaatat ctaaaattca atttggaggt ataactagca tatgtataaa attggtgaaa
    36901 gtgtaatgta tccaaaagag ggagcctgct ctgtaaatga tattgtaaca aagaaaataa
    36961 atcatgagat gcaaaaatac tatgaattaa gtgtcatttt taatagtaac cttaaaattt
    37021 cgattccagt tctaaatgca gatagaattg gcatacgtcc agttatggat ggaaatgatg
    37081 ttgataattt tatccaatct attaataaaa cagatggtgt atggattttt gatagaaaag
    37141 aaagacttaa actgtaccaa gataaatttc attcaggaga tgtttttgaa attgtaaaat
    37201 taatcaaaat gcttatgata caagacagtt caaaacaatt gtgtagcaca gataaggagt
    37261 ttttaaataa agctcaaaaa tttgctttat cagaattagc tgctgctcaa tgtaaatcct
    37321 atacaatggt attagaggaa atgaaaaaac atatattaaa ttcaaagaat ataaattaaa
    37381 ccagtttttt aaactggttt tattttttat actaatcatc catgctactt tagcttattt
    37441 taaactgcct aatctaatat taataaagtt atctcaatta gatagatgta ttttattcaa
    37501 ataaaaaaaa ctaagagtaa atcatattac tgatttactc ttagctaata aaatttaatc
    37561 ttcttcaagt tcttttttct cttgtagtaa tacacttaat tcatttgctt ctaaaacttg
    37621 tgcctctgca atatcaagta actcttgttg ccattccaca catttatctt tgtaatcaaa
    37681 aggtagcgtt ctgtcaacta tgtacttatc aatacagtcc tccgcacttt taattatttc
    37741 ttttctttca tcaataaatt tttctaattc tactaaggct tcttcataag cttttctact
    37801 catataaatt ccccctttgt acaattattc tacattaaaa tgatttttcc tcttttttgt
    37861 ataaaatttt atttgtatat aacttttcca tcaatatctt ttatagtttg acatccagtt
    37921 aatatcatag aactacttag ctctgattga agtttattta cataagtttc tacaccatca
    37981 gttgcaccac caaaagaagc agtcacaaaa ggtcttccta ttaatactgc atctgcacct
    38041 aaacctatca tttttagtac gtctaaacca gttctcactc caccatctgc aagtattgta
    38101 actttacctt taacagcatc agcaattttt ggtaaaactt cacatgctcc tggtgtacag
    38161 tcaagcactc ttcctccatg atttgataca actattgcat ccacacctgc ttctactgcc
    38221 attaaagtat cttcaacagt cattatacct ttcaatataa atggtagttt agtagacttt
    38281 actaactcct ttatttgttt aacattttta ggaagtactg gttttccatg taatgataaa
    38341 gttactagac cacaggcatc tatatcaact ccaactgcaa atgcaccagc ttcttcagct
    38401 aatcttatct tttttataat attttcatta tcccaaggtt taataaatac aattccagct
    38461 ccattatact ttttgactac atctaaattt tccattaaaa aagcatctac tgccgtatca
    38521 ccaaccattg cataaatacc actattagca catcctgcaa ctactggttc tatgtaatct
    38581 ctttcattaa tttttccacc catatttaaa gtagttcctg ttactggagc tgcaaatata
    38641 ggtgcactca ttttctttcc aaacatctct atagatgtat caggatttga tacatcatgt
    38701 attactctca tatttacttt tactttttct aaactcttgc tattttctat aaaagaagaa
    38761 ccacttcctt tacctcccat gccaggcact tcacctgcac aagcaacccc attacaaacc
    38821 ttacaaactt tacaacttcc atttaaattt tctctagcac tttttaataa ttcattatat
    38881 tccatcttta atcccccatt aactatagta atttatatta tatacattat atcatattat
    38941 atttacagta tatttttcaa aaaacttttt ctgtggatag gagttatgcc atatttttca
    39001 atagcttcat agtgttcttt agttccatat cctttgtgag atttaaaccc atattctggg
    39061 tatactctat catattggta cattatacta tccctagtaa ctttagcaag tatacttgct
    39121 gctgctattg atatagattt tgaatctcct ttcacaattg gattttgaga tatgtcaata
    39181 cctggtattg ttgctgcatc aactaataaa taatctggtg ctttttttaa acaatttata
    39241 gcctttttca ttgccatata tgtagcattt aatatattaa attcatctat ttcttcattg
    39301 tttactatac ctattccata atctagtgct tcttctttta ttacttcaaa aagttcatct
    39361 ctttttgcct cactcagttt cttagagtca tttacacctt ctattttggt atctttttta
    39421 aatactacaa cagaagctac aacaggtcca gcaagtggtc ctcttcccgc ctcatcaatt
    39481 cctccaatat ataaataacc tttatcatag ccttcgttct caaatatatt tatagtttcc
    39541 aatctttctt cttcttttct aatattatcc agcttttttg ctagttttat agctagacct
    39601 tgtacagatt ttctttcatc aactcttaac agctctatat attccatata tttttctact
    39661 tctaaagtct ctattatttc tttaatctcc ctcacacttt tatcctgcat accattccct
    39721 catctttcgt ttttaaaaat ttaattttta aatatattaa aattttttaa ttagagttta
    39781 attgcatcca ctatagccac attttaaaca tatactacat ccacctgtat gtgcaattcc
    39841 ttcacttcca cactcagggc acacaaattt ttcatcttct tcaaaatttt tatttattat
    39901 ttctttggct ttttcatctt tattatcttt ttctttttta ttatttttat aatattcttt
    39961 tttactattt tcttttttat cttctttatt attttcttcc tttttttcat ttattaaaat
    40021 tccactcctt ttacatccat ctctaaatat tgttactcct ttaagaccag cctcccatgc
    40081 cttaatatat atattgaaaa catcttcaac tgtagtttca aaaggtatat ttattgtaga
    40141 tgatatagaa gcatcaatat acttttgcca tactttttgc atgtttattc tttcttcata
    40201 tcctatattc atagcagtaa caaaaaaatc tggtaaacat tcttcatctg taataccttt
    40261 cttgtccata tactctttaa caattggagt atatacttta taatacacat cctcatcatg
    40321 taagctttca gtttttctta tatatgaaag attaaatata ggttctattc caccactgat
    40381 acctatcatt gtagatatgg aacctgtagg aggtatggtt aaaagttgtg aatttctaag
    40441 cccatacttt ttaaccattt ccttagtgtc ttcatttaga ttttctataa aaaacttaga
    40501 tttagaaata ttttcatatt tatactcact aaatgttcca tattctttag caattaatgc
    40561 tgattgcttc acagcttcat ttaacatagt cttaccaatt aaatcacata gttctaaaga
    40621 ttcatcagaa ccatatctta ttcccatttt tataagcata tcagctatac ccattacacc
    40681 taaacctatc tgtctatact tatgtacact atctctttgt tcttgtaatg gatgcaagtt
    40741 caatccctca tctaagacat catttaaagc tactacagct tctctaacgc aagattttaa
    40801 tttattaata tcaaaagtag catgttcacc aaatggttgt attataaact ctgacaagtt
    40861 tattgagcca agtagacaac ttcctccact tggaagtggt tcttctgcac aaggatttac
    40921 tcctgaaaag caaaagttct tatcttcact cataaaatta tatgttttta ttttatccca
    40981 aaacaatata cctggttctg cataatccca gttatttttc acaaatttat taaataaatc
    41041 ataagcattt actatcttaa ctattttttc tccagtagtt tcaacttcaa aagtacaatt
    41101 atataacttt ttttctctta cagcttgcat aaattcatct gttactctca cagaaatatt
    41161 tgctttagta accttctcca aatctgtttt tatatctata aagtcttcta tctctggatg
    41221 atttacatcc atagaaatca taagagctcc tcttctccct ctttgaccaa ttaagccagt
    41281 tgtcatactg taaagttcca taaaagagac tgctccagtc gtatgttttg cagcattgtt
    41341 aactttcgct ccttttggtc ttagctttga aatatcaatt ccaactcctc caccataact
    41401 aaaagttcta gcaagttttt ttgcagtatc aaatatatct tctatgctat cttttggtgg
    41461 ttctattaca taacaattag aatatgttac tttttttccc tctttctgta atcctctatt
    41521 tgctaaaatt cttccagcaa atagaaatct tttttgcctt attagttttg atattcttga
    41581 actattattt gaaattctct ttatccattc atcaaaactc tcaccattat gtctatactt
    41641 gttcttccat attgattttt gtaattcatc aaactcccaa gctttagtcc ttatttcaga
    41701 gcgtctttct ctatataata tgtagtgttt tgctatatct tttctatttg attccataag
    41761 tagtacttca actatatctt gtatttcttc tacggataag catttttcca tagaattata
    41821 gtcattagct atttttcttg atatatcata tgccaactct ctatctactc caccttcact
    41881 atttatacta gctttataga cagcatcttc aatcttactt ttactaaaaa gttcttttgt
    41941 accatctctt tttattatgt atttcatttt taaacctcca ataaattagt attaaattaa
    42001 tacacacatt aactataact ctaaacaaac tttttatata tttgtatatt ttcatattaa
    42061 ttatctaaca taatatat
//
LOCUS       DAEORM030000031        41593 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.031, whole genome shotgun sequence.
ACCESSION   DAEORM030000031 DAEORM030000000
VERSION     DAEORM030000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 41593)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41593)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 41593)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41593
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.031"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            257..1687
                     /locus_tag="KRH23_002191"
     CDS             257..1687
                     /locus_tag="KRH23_002191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4116 domain-containing protein"
                     /protein_id="HHS5225469.1"
                     /translation="MDIKNKIKSIFLPEKNDYLDDEEFEYDIENNEEDLKEDNKVHLN
                     DLSRVKYDYRELKDIENQTEEMCLLAVKQDGTIIEFVKDKTYKVCMEAVKQTYKALKY
                     ITNQNEDICIEAVKQNYRALYYINNKTENVLIEAIKNASTYDVMEVFKFVEEQTEDVC
                     LAFIERASKNDVAEILKGIKEQTPAICLEAVKKDGKSLAYVKEQSNSICLEAVKENYS
                     ALSCVKEQTEEICIEAVKQNDFALYYVNEQTEKICMEAVKRSYMALQYVNKQTEEICL
                     EAVRIDGRALQYVKEQTEEICLESVRQNGKVLQYVKKQTENICIEAVRGSFEELEIKE
                     ILSYVKIPTERIFIEAVKQNGKILKYVENQTELICLEAVRENYNALAYVKEQTEEICL
                     EAVNQSYEALKYVKEQTEEVCLKAVKQDYRMLKYVNNQTEKICLEAVKQNYRALEFVD
                     NQTEKVCLEAVKQNRKALQYVKQKQS"
     gene            2055..2633
                     /locus_tag="KRH23_002192"
     CDS             2055..2633
                     /locus_tag="KRH23_002192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator ArgB-like protein"
                     /protein_id="HHS5225470.1"
                     /translation="MFKRYAEKMTSVLICNNMIDNNESKVYSYGFEILIAFIVNITTM
                     LFIGFLFGKFTYVLFFLMCYCPIRQFSGGYHADNYFRCLLTFIFIILSTILIIENINI
                     DLFKNIIMIIASVSWVGICVLCPIEHRSNPISDREKLVYKKTAIFISTVVLLITILSL
                     SLSIFVDYFTYSAFAMFWIFVMLVLGKLKAKV"
     gene            2687..2809
                     /locus_tag="KRH23_002193"
     CDS             2687..2809
                     /locus_tag="KRH23_002193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic lactone autoinducer peptide"
                     /protein_id="HHS5225471.1"
                     /translation="MKFASSLALSTAILSANSTCPWIIHQPKVPKEISNLKKTN"
     gene            3114..4493
                     /gene="scfB"
                     /locus_tag="KRH23_002194"
     CDS             3114..4493
                     /gene="scfB"
                     /locus_tag="KRH23_002194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0031179 - peptide modification [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioether cross-link-forming SCIFF peptide
                     maturase"
                     /protein_id="HHS5225472.1"
                     /translation="MSMIHKFSMNGYNIVLDVNGGAVHVLDDVAYDLLDFYKEKSKEE
                     ILEILKSKYQEEKINEAYEEILNLEKEGLLYTEDTYQYHPSFVHREPVVKALCLNVAH
                     DCNLKCKYCFAAQGDFGGEKELMSFEVGKAAIDYLIANSGSRKNLEIDFFGGEPLMNF
                     EVVKQLVDYGRSVEKDYNKNIRFTITTNGVLLNDEIIDYINENMHNVVLSLDGRKEVN
                     DNMRPTLNDKGSYDITLPRFKKLVEKRAKDKYYYIRGTFTRDNLDFSKDVMHFADLGF
                     KLTSVEPVVGDESNPYALREEDLPKIFEEYEKFAVEYADRQLQGDGFKFFHFMIDLNQ
                     GPCVIKRITGCGAGNEYLSVTPNGDIYPCHQFVGNEEFKMANIFDEEIVLPENLKNMF
                     REAHVYTKEECKQCWNKFYCSGGCHANAINFNNDISKPYELGCEMQRKRTECSIMIQA
                     KLMLEGATN"
     gene            4522..5019
                     /locus_tag="KRH23_002195"
     CDS             4522..5019
                     /locus_tag="KRH23_002195"
                     /EC_number="4.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HHS5225473.1"
                     /translation="MIRDYLEDKPLIDESVFVAKSADVIGNVKIGKDSSIWYNAVVRG
                     DEGPITIGENTNIQDCSIVHGDTETIIGNNVTVGHRSIVHGCKISDNVLIGMGSIILD
                     NAEIGEYTLIGAGTLITSNKKFPPGVLIMGSPGKVVRELTEEDKKYIDESYEWYLEAA
                     QNQKY"
     gene            5317..6981
                     /locus_tag="KRH23_002196"
     CDS             5317..6981
                     /locus_tag="KRH23_002196"
                     /EC_number="2.7.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004672 - protein kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC1 kinase family protein"
                     /protein_id="HHS5225474.1"
                     /translation="MRISYRNLKRYREIGYVLIKYGFSFIVERLNIEGIAYKIPLFDP
                     PEEIKNMTTGERMKRVLEELGPTYIKIGQILSTRKDLLDQDIIDEISKLRDDVEKFDS
                     NIAIDIFKEEVGLSIEEIFLEFKEEPIAAASIGQVYEGVLKTGEEVIVKIQRPNIEKI
                     IKSDLEILRTIANTLKDLKKDFNLDLVQMIEEFQTQLMRELDYTFEAINATKFSRIFK
                     NSDEVYIPKVYSEYNTKKILVMEKVNGTKLSDVEKIRRLGYNTKTIVEIGVRSFFTQV
                     LSHGFFHADPHPGNIFVVAKNKIAYIDFGMIGIIDNKTLNQLNEIALAGVEKNVDKII
                     YLLIEMDALNGEADIKGLRQDLLYLIHYYYDISIEKINVTDILNELFRFFRQYKIVMP
                     AQFVTLAKTVITLEGTSRTLNTDFSFGSMGKEFMKHHYKSKFNPKNVVLSSRQNVEEI
                     LLDIKTIPKQLKAILKNIERNNIKMQIEDVKMTRLENCIIELTSQISLSLVLASIIVG
                     SSLIIASPNIENNIWIKFTAIAGFFISFIIGLCLVIRSIRSKYKKD"
     gene            6994..9444
                     /gene="recJ"
                     /locus_tag="KRH23_002197"
     CDS             6994..9444
                     /gene="recJ"
                     /locus_tag="KRH23_002197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008409 - 5'-3' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HHS5225475.1"
                     /translation="MKKWILKYKGKIEESEFSKKLNISPEICQILKNRGICTEKDSEI
                     FMNPSLDYLRDPFLMKDMQKAVDRIKLAVEKNEKIWIYGDYDVDGVSSTSILCLYFKS
                     IGYNVDYYIPNRLEEGYGINEDAIKLISSRGCDLIISVDCGITSVSEVNTANDLGIDV
                     IITDHHECQSEIPSAFAVINPKQEDCNYPFDSLCGCGVAFKMIQALTPKEEFKTSMYN
                     YLEIVTLATICDIVPLIDENRIIVKNGLKSMKEGKNIGLRELIKVCGVESDKIGSSHI
                     GFAIGPRINASGRLGYSYLGVELFTTQSQEEAVEIASILEEKNNERQMIEAKMYHEAE
                     EMLKSNSRYNDDKVLVLAKEGWQHGIIGIVASKLTEKYYKPTILLGIENGEATGSARS
                     IKGFNIFEALIKCKDLMTKFGGHEQAAGLSLDSDNVEILANEINKFADYNLTEDDMIE
                     NVNVEFELQENVINLNLVEELHKLEPFGLNNPNPRFIVRNYILKDLKVIGKNQQHLKL
                     SIEKEKSYECIGFNMSHLKSMYKVGDKVDVLFQLDENNYMGNRKVQFLLKDIRLARPK
                     SASNDKLSLKLMSKIIPKDTQSLYNISVSDFELFDGNTDINIFDYFEKDTLIISNSIN
                     GFYRAMSDISLIDLDFNINYNIIEDVSKNTDKLELIFSPNIDKIDLKRYNNIILYDYL
                     YNKGEYSYIYENKREESEIIKYYNKTDLLYLKNVVSNIVPSRDEFITIYKQALIKKEI
                     DLDMVNIRETFNVIPLKFFTILNVFRELNLLDFNLNYEKNSVLIRILPKPQKKLDLNE
                     SLILNNLKNLEKQYNSSY"
     gene            9457..9969
                     /locus_tag="KRH23_002198"
     CDS             9457..9969
                     /locus_tag="KRH23_002198"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003999 - adenine
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0006168 - adenine salvage [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HHS5225476.1"
                     /translation="MDLKNFIRNIDDFPKPGIDFKDVTTLFKDGDAFKYAVDSIVEEL
                     KDKDVDLVIGPEARGFLMGTPVAYALGVGFVPIRKPGKLPGEVESYEYGLEYGTDTLE
                     IHKDAIKKGQKVAIVDDLLATGGTMEAAAKLVEKLGGEVVSMQFLIELKFLNGREKLS
                     NYDVNSLIKY"
     gene            10043..12250
                     /locus_tag="KRH23_002199"
     CDS             10043..12250
                     /locus_tag="KRH23_002199"
                     /EC_number="2.7.6.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008728 - GTP diphosphokinase activity
                     [Evidence IEA];
                     GO_function: GO:0008893 - guanosine-3',5'-bis(diphosphate)
                     3'-diphosphatase activity [Evidence IEA];
                     GO_process: GO:0015970 - guanosine tetraphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RelA/SpoT family protein"
                     /protein_id="HHS5225477.1"
                     /translation="MHDKELQEIIEKIKVYAPNANFEMVEKAYNLAKKAHEGQYRKSG
                     EPYFIHPLAVANILIEMELDIETITAGLLHDVVEDTEYTYEDIKKEFGKEVADLVDGV
                     TKLGQIKYRSKEETQSENLRKMFLAMAKDIRVILIKLADRLHNMRTLKYMPPEKAKYK
                     AKETLEIYGGIAHRLGISKIKWELEDRALRFMDPEGYYDLVSRVSMKRSQREDYIQGI
                     VELLKDKFKDLSIPCDVYGRPKHFYSIYRKMQKKHKTFEEIFDLTAVRILVDNVKDCY
                     AVLGIVHTLWRPIPGRFKDYIAMPKPNMYQSLHTTVVGPDGEPLEIQIRTHEMHNIAE
                     NGIAAHWKYKEGISSKESKVEEKLQWLRQMMEWEKDLKDPQEFMDALKEDVFNSQVYV
                     FTPKGDVIELPAESTPIDFAYRVHTNVGNKCVGAKIDGRIVPIDYKLQNGNIVEVLTS
                     SNSNGPSRDWLNIVKTPNAKSRIRQFFKKERREENVDRGNTILEREFKKHDIPQKDPL
                     VEKYMALVAKKFNQPSVEDLIATVGYGGIMSSQVVSKVKDLYLKEVKKAKKEQQIQEE
                     DLNKHNISETEYSKKRKKNASQGIIVKGLDNILVRFAKCCNPLPGDEIVGYITKGRGV
                     AIHRADCPNANNNGDFFQNRLVEVSWSSAGKGKFEAEIQIKAIDRRGIVNEITHIVAM
                     DKLSLNGINARKGKDSIVSINLLVEVNDTEELKILMKKLKAIPGVESIYRMTN"
     gene            12275..12724
                     /gene="dtd"
                     /locus_tag="KRH23_002200"
     CDS             12275..12724
                     /gene="dtd"
                     /locus_tag="KRH23_002200"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004045 - peptidyl-tRNA hydrolase activity
                     [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacyl-tRNA deacylase"
                     /protein_id="HHS5225478.1"
                     /translation="MRAVVQRVSSSKVTVDENTIGQINKGLLVLLGVTHDDKSSDVDY
                     MIDKILNLRIFEDENDKMNLSLMDIGGELLVVSQFTLYGDCRKGRRPGFSNAARPELA
                     NNLYEEFVKKAKDKGVTVGTGQFAAHMMVELTNDGPVTILLDSSKSF"
     gene            12739..13353
                     /locus_tag="KRH23_002201"
     CDS             12739..13353
                     /locus_tag="KRH23_002201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HHS5225479.1"
                     /translation="MIIKKFVDSYFGVNTYVLGDEKTKKCAVIDPGGSLVETLSFVKE
                     NELNIEYIILTHGHGDHIGYVKDIKEKTCAKVVAHVDEKELLNDKNKNLSYTMRCGAQ
                     EFDADIYVNDKDKLELGELKMTFLHTPGHTQGCMCIRVEDEMFTGDTLFAGSIGRTDL
                     YSGDFNQMEKSLKKLCKYEDAVRVYPGHGPTSTLGVEKKTNPYM"
     gene            13444..15000
                     /locus_tag="KRH23_002202"
     CDS             13444..15000
                     /locus_tag="KRH23_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="coproporphyrinogen III oxidase"
                     /protein_id="HHS5225480.1"
                     /translation="MLYVFLKGHDYKYEVAELIKLFTSEFKFKDSNANNNIESKHLIN
                     RLIYENGVLFSSTEYYENGNLKYESIQNIKNMNLEFLDGFDSSKTIEEFLNSLDSESK
                     RNFKKLCKENIKKSMFLVLKQVFNSYVPWGILTGIRPVKIVHNLMDKKLDDNSIRTIL
                     KDNYFIIDEKIDLALEIAKRERLFMYPIDKNKISLYVSIPFCPTRCVYCSFPSNSLKQ
                     FGHLKREYVYKLIEEIKGFAKVIKETKKEVETLYIGGGTPTTLDEEELDLLINSLFNE
                     LDLSKIKEFTVEAGRPDTITEQKLRVLKKHNVSRISINPQTMNDDTLVKIGREHRVSD
                     LVDCFNMARRMGFDNINMDIILGLIDEDLNMVKNTLEEIKKLSPESLTVHTLAIKRAS
                     NLNINMDRYKEHLTQYEEMVKMIDLSMKYAKDMGLNPYYMYRQKHMLGNLENIGYAKE
                     GYECIYNIQIMEEKQSNYALGAGAISKFVYVDEDRIERVENVKNVEQYIERVDEMIKR
                     KKEEVYKNVD"
     gene            14990..16252
                     /gene="hisS"
                     /locus_tag="KRH23_002203"
     CDS             14990..16252
                     /gene="hisS"
                     /locus_tag="KRH23_002203"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004821 - histidine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006427 - histidyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HHS5225481.1"
                     /translation="MLTKAPRGTKDITPKEAYKWRYVENKFREICALYGYEEMVTPIF
                     EHTELFKRSVGDTTDIVQKEMYSFKDKGDREITLKPEGTAGVVRAFIENKLYADTQPT
                     KLFYVTPCFRYERPQAGRQRQFHQFGIEALGSDTPSMDAEIIALAVQFFNEVGLNDLV
                     VSINSVGCPVCRKEYNALLKEYLDSKVDILCDTCNERREKNPMRVIDCKNPTCKENIK
                     DIPFIADHLCDDCKSHFDKLQEYLKEMNINFVIDKTIVRGLDYYRKTAFEIISNDIGA
                     QSTVCGGGRYDGLVEQLGGPKGISGIGFGLGIERLLLTLEGNGIEIENPQSTDIFIVT
                     IGEEANTRSFKLLKDLRQNHISADKDHIERSVKAQFKYSDKINSKFTIVIGDDELKND
                     TATLKNMKTSEQTTVKLSTLVEELKQKL"
     gene            16326..18113
                     /gene="aspS"
                     /locus_tag="KRH23_002204"
     CDS             16326..18113
                     /gene="aspS"
                     /locus_tag="KRH23_002204"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA];
                     GO_process: GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HHS5225482.1"
                     /translation="METLKGLKRTHYCGELREKNINEEVVLMGWVQKKRNLGGLVFVD
                     LRDTSGLCQIVFDTDVDKEAFEKAEKLGAEFVIAVKGKVCERQSKNPNMPTGDIEIFA
                     TELRLLNKSETPPIYIKDDDDVSEALRLKYRYLDLRKPSMQRNLKLRHKVMNITRNYL
                     SNNRFCEIETPFLIAPTPEGARDYLVPSRVNPGKFYALPQSPQLYKQLLMVSGMDRYF
                     QIVKCFRDEDLRADRQPEFTQIDCEMSFVEQEDVMSMIEGLLEAIFKEVLDVELALPL
                     PKMTYAEAMSKYGSDKPDTRFGYELTDISDVVCNCGFKVFADATQPGKSVRGINVKGK
                     ADDFTRKQISSLEEHAKTYRAKGLAWMKVGQEGVTSPIAKFFNEEEMNAILTRMNAEV
                     GDLLLFVADKNSIVFDALGQVRLEVANRLNLLDKNVYNLLWVTEFPVFEEDEETGTFS
                     AMHHPFTSPMDEDLDKLEEGDKSSLRAKAYDIVLNGYEIGGGSVRISNSDVQSRMFKA
                     LGFTEERANEKFGYLLEAFKYGTPPHAGLAFGLDRLVMLLAGTDNIREVIAFPKNQNA
                     VCPMTNAPTLAEDEQLEELSIKVDIKDNE"
     gene            18572..19804
                     /locus_tag="KRH23_002205"
     CDS             18572..19804
                     /locus_tag="KRH23_002205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytosine permease"
                     /protein_id="HHS5225483.1"
                     /translation="MQEREELVLNPVPKEERVGWLAPLFNMLGSNIAISELMVGGTLI
                     LGMTLSNMIITSIIGNLILVAIIMIQGYIGYKEGLNTYVLAKGAFGEIGGKYLISLLL
                     GITSFGWFGVQAGVAGLSVQKIFPSVNLTLVTVILGLFMVVFALYGFKAMAKFNYLVI
                     PPLMILMVWGVFKAFSTYGVEAIYNYTPQTTMSMVEGLNIVVGLVIVGAIISPDQLRY
                     TRRVKDIWIISFLGLGIISLFQQVAAGVMSMGAPTWDITEVLANLGFGWVAFVILILA
                     SWSTNVSNAYSGGLALKTIFPNVKRNVLTLVAGLIGTIIAATGIIFKFQSFLSFLGIA
                     VPAIAGIMWCEYYFIQGRTYKHREGINWIAVISWLIGFAASYYSSKINFLIPPINGIV
                     VSMVIYYILMKCFGIKDK"
     gene            19818..20624
                     /locus_tag="KRH23_002206"
     CDS             19818..20624
                     /locus_tag="KRH23_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitrilase-related carbon-nitrogen hydrolase"
                     /protein_id="HHS5225484.1"
                     /translation="MGRKVKIGIIQQHSVLGNVKKNIEKAVEMIDDLGKQGADIICLP
                     ELFATGYNLESLGGVKTLELIREHNKYIEESMSEAAKRNNVYLISPYGTLEKGSTHVY
                     NSAVIFDRKGKIMGEYCKNHLWSLEAVYFKGGEKVEVYDADFGRFGVMICYDAGFPEV
                     SRELTLKGSEIIFIPSAWRIQDEDMWDLNVSQRALENTVYTVGVNLVSNDSNLILFGK
                     SKICNPRGTVITQLDTYREKYVLSEIDLDEIKKYREDIPYLKDRKSSYNI"
     gene            complement(20736..21605)
                     /locus_tag="KRH23_002207"
     CDS             complement(20736..21605)
                     /locus_tag="KRH23_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HHS5225485.1"
                     /translation="MDLLHLKYFQTVARMEHITKASHKLNIAQPALSKTISSLEKELG
                     VQLFDRKGRYIVLNEYGRLFLKRVDSILDLVESSKKELQDTSLENSGEVKILSPAAAN
                     VLPSLLSNFRKLYPNITFNVSHTLPSSYKKSDFDLYISSSFTKLNSENSITLTCEEIL
                     LGVSINHPLSLKDEVYLSEVSDENFIVITKGENYREVIDILCESANFKPKIAFESDSP
                     YTIYALIKSLQGVGFICGKSWGLSQDPEIKLLHIKDIEFKRYLNLSWFSENYESKAVL
                     LFKNFLINYFKNI"
     gene            21977..23404
                     /locus_tag="KRH23_002208"
     CDS             21977..23404
                     /locus_tag="KRH23_002208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp14"
                     /protein_id="HHS5225486.1"
                     /translation="MKLTKSISSMLCLSLVLSLSPVAYANEISRTTVENTLVGQDRYQ
                     TAVEVSKKGWSSANEAVVVNSESIVDALAVTSFAKLKNAPILLTEKNNLNSQTEKELK
                     RLGVKKVYIIGLSSSVSNDVQKQLESNNLTTDRVGGSDRYQTALSIAKKIEGLKDISE
                     IAVVNGYTGLADAVSIASVAATNGMVILPVSDASGISSFKDFIESKNINKSYIIGSTN
                     AVSDKIKQSLPNSERIGGADRNETNGKVIEKFYTSNKLNNVFVAKDGMKNQNQLIDAL
                     AVGVLASKENSPVLIVGEQLSATQKSVFSNKNATSITQVGSGGNENAFKELKDLQANS
                     NNKRVMYVTNTDKVNIRNDATIEASVIGYLNNGDEVEVLDVLKTGWVKIKYNEGIGYV
                     SGSYLTNNKPDNSNENIKIKYVKEKDGLNVRKGPSTEDEKIGHLSYGSKVETIEMFAT
                     GWVKIKYNGGYGYVSNDYLSDTPVI"
     gene            complement(23480..23749)
                     /locus_tag="KRH23_002209"
     CDS             complement(23480..23749)
                     /locus_tag="KRH23_002209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5225487.1"
                     /translation="MKFEYYYLIQDIAGILLAFIGLRMSIIGFRILSMKGLSRNTLLI
                     VIKYCLFTIAGLNLLISKFGIRHWIWSVCMLIISIIINPRIKVSK"
     gene            complement(23752..25194)
                     /gene="nhaC"
                     /locus_tag="KRH23_002210"
     CDS             complement(23752..25194)
                     /gene="nhaC"
                     /locus_tag="KRH23_002210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA];
                     GO_function: GO:0015385 - sodium:proton antiporter
                     activity [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HHS5225488.1"
                     /translation="MKMNTERKIPSFRYSLLVMLAIIALTSVGIVVFNASITTMFLLS
                     WLIVVPAAMKLGYTNDEIEAFGFEVGKDAFQSNLIILSVGVLIAAWIAAGTIPTVVYS
                     GLTIITPKYFLLTTLIVCSLTSVATGTSWGTLGTSGIAMMSIGTSMGIPLGLTAGAVI
                     SGAFFGDKMSPLSDSTNLAAAVCKTDVITHMKHMFYTTGPAYVICIVLYTVIGFKYSN
                     NTIDYVQINQIKDVLNSNFHIGLVAMIPIIFLLLLLLLQKPPIISILSSAIMGLIIAV
                     FQEGEKIGDVLNYMLSGFTIDTGFVYADKLLNRGGIMSMAETVLLVFVVFVIAGILQK
                     TGFLEVLLQPLITKIGKSRTKLVGSTFIVSYFANAFSSSMMFTSVFVGTLMSPIYKEF
                     KLKPQNLSRIIEDTATLGGPLIPWNSNAVFCAQTLGVSPLEFIPYCFLSWITPIISFI
                     YGVTGFTMLTYTDDEIEELEIFDTAQRRVD"
     gene            complement(25219..26385)
                     /locus_tag="KRH23_002211"
     CDS             complement(25219..26385)
                     /locus_tag="KRH23_002211"
                     /EC_number="4.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0047804 - cysteine-S-conjugate beta-lyase
                     activity [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MalY/PatB family protein"
                     /protein_id="HHS5225489.1"
                     /translation="MNYNFNEIVDRSNNFSSKWSEMEKKYGTNDLLPMWVADMDFKAA
                     PCIIDSLKNRLEQEIYGYTTRPDSYNESIVNWLDRRHNWKIKSEWLIYSPGVIPAISL
                     LINELTKANDKIMIQEPVYSPFNSVVKNNNRELIISPLQKLENGNYIMDYEDIENKIK
                     DVKLFILCNPHNPVGRVWTKDELKKLGDICLKHNVKIISDEIHSDIILKKHKHIPMAS
                     ISKEFEKNTITCMAPTKTFNIAGLQSSYVVLPDEKDYKLLDDAFTRIDIKRNNCFSLV
                     ATEASYNNGESWLESFLEYLESNIDFAIKYINENMPKLKVRKPEGTYLLWVDFSALGL
                     SDEELESILVQKGKVALNQGNSFGIGGSGYQRINLACPRSMLEEALIRIKNAIN"
     gene            complement(26610..28730)
                     /locus_tag="KRH23_002212"
     CDS             complement(26610..28730)
                     /locus_tag="KRH23_002212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54 interaction domain-containing protein"
                     /protein_id="HHS5225490.1"
                     /translation="MKQMELAIVSLKKDAGEIYENQIRQFLGDNLKINLYSFEEGNLK
                     FFKEKLILLSAYLKYDEIVKLSHSDAQIIVPKLTFEKNSIDMISKLEKDKIIYVYNLS
                     KDMAIETISLIHRLGIDNINILPCYPEIEFTPTDAVILTPGEKILPKFKNCEVIDLKY
                     RIIDLSCIVEIATKTKLKHLIKDDLIKKYVEKIIPTSYSTGELLLDANKFERQFDLLL
                     SIIDDGIICTNNDGIIQFYNHMARKILSINANEMIDSFVGDCIKDINFQSILTNKTPF
                     FEKLIKINHIDINLEIKHIQLNVFDGFILKMTKFSQLEKKQAKLRAQLVNSGNISKYT
                     FDDILGSSIQTINTKKIANKMAQSNSSILIIGESGTGKELFAQSIHSASRRKDGPFVA
                     VNCSTFQENLLQSELFGYDEGAFTGAKKGGKIGLFELANNGTIFLDEIGEMDLNSQSK
                     LLRVIQEKQVRRIGSNNVIDIDVRIIAATNRNLKELVSKNMFRRDLYFRLNVLPLKIH
                     PLRERPADIFEIFGSLKYDIPCNFILSEEVKEIFKMYRWEGNVRELRNLGEYFCYLEK
                     DIIEICDLPEYILDTIDSNYSRTVCNKVSDNIKKYQFNIGKDKNIMKYDYNFKRSLDE
                     YIFILDNLKKAYDLKERIGRKSLCKIALEENRFLTEQQIRNMLLELQNFGLVDILVGR
                     GGSIITSKGVEFLKNINRSNKLNS"
     gene            28963..29364
                     /locus_tag="KRH23_002213"
     CDS             28963..29364
                     /locus_tag="KRH23_002213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5225491.1"
                     /translation="MKKCLYCNRDIKSPNNKLAIKYDDNMNIYPCRAECKEKIEEYIA
                     KKPTYKFINILEVLLGVGGIFCFLSKWTIAAQVVLGIDALVIFLFPLAGFKMNGKLSM
                     EQTKNQSRSIAISILAFIVIITVLYFKQVGK"
     gene            29407..29700
                     /locus_tag="KRH23_002214"
     CDS             29407..29700
                     /locus_tag="KRH23_002214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HHS5225492.1"
                     /translation="MEERKLAPNNEREALIKRLKRIEGQVKGIQKMVEQERYCVDILV
                     QISAIRSAINRVGTIILENHIKGCVAESIKHDDADKTEEMIKELMDTINKFTK"
     gene            29715..30155
                     /locus_tag="KRH23_002215"
     CDS             29715..30155
                     /locus_tag="KRH23_002215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SoxR reducing system RseC family protein"
                     /protein_id="HHS5225493.1"
                     /translation="MNQQGFIMEIVDDRTAKLKMQRHSACAACGKCATTNSAESKEIL
                     VEVDNTIGAKVGDHVEVSMDNMNVLKAAVMAYIIPLIALLVGTIGTYYILGAIGMTTG
                     VEAISGLVGICLTIICYLYLKKNDKKFRDSREFIPVITRILIDL"
     gene            complement(30247..30720)
                     /locus_tag="KRH23_002216"
     CDS             complement(30247..30720)
                     /locus_tag="KRH23_002216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HHS5225494.1"
                     /translation="MTDMSMILHFLFSGVATAGFAVFFNAPLYLLLPAGVTGGIGWIV
                     YVYLFNFTTNAVFAGFIAAALVSACSETLARKLKQPAIVFVIPGILPLIPGIGLYNTM
                     LSLIQKNYSLAMSKGTDALFLSAAIALGVLVVTSFVRTLNLLKIRKNFIPYRKSK"
     gene            complement(30720..31508)
                     /locus_tag="KRH23_002217"
     CDS             complement(30720..31508)
                     /locus_tag="KRH23_002217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HHS5225495.1"
                     /translation="MNQNEELEYKKNILKLALFVGELMIKNGAETSRVEDSVLRICRS
                     RGFYHVNIFTTPTVIIISDEKFDGFSFMKTIQSRGINLNKISLLNSFSREFVSDKEYD
                     IDNAIARLYEIQDVKPYPLWLFYSCTGIASACFACLLGGNYVLNFILTFIIAIFAAIT
                     YDKTMKISAISAFSCLVSSFLIALSGVLLVEIGILDDPKMLIVGAIMPLLPGVAFIKA
                     IRDLISGNLISGISRAFDAAMIIIAIASGVGFVLDTWYRIGGPF"
     gene            31836..33080
                     /gene="glyA"
                     /locus_tag="KRH23_002218"
     CDS             31836..33080
                     /gene="glyA"
                     /locus_tag="KRH23_002218"
                     /EC_number="2.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004372 - glycine hydroxymethyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0070905 - serine binding [Evidence IEA];
                     GO_process: GO:0019264 - glycine biosynthetic process from
                     serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HHS5225496.1"
                     /translation="MFENLKKADPEIYESMKRELKRQQRNIELIASENIVSVPVMETM
                     GSHLTNKYAEGYSGKRYYGGCEYIDEVETLAIDRIKKIFGAEHANVQPHSGANANIGV
                     YFAMLKPGDVVMGMNLSQGGHLTHGAPVNISGQYYKFYEYGIDKDSGLIDFDEVRKIA
                     HEVKPKMIVAGASAYPREIDFKKFREIADEVGALLMVDMAHIAGLVAAGLHQNPCEVA
                     DFVTTTTHKTLRGPRGGVILCKEKYAKDIDKAIFPGIQGGPLEHIIASKAVCFKEALS
                     DEFKEYQVQVAKNAKALAEELIKRDFKLISGGTDNHLILLDLTNKNITGKAAEKRLDD
                     AYITANKNTIPFDPNGALVTSGIRLGTPAVTTRGMKEEDMAIIAEAIDLCLTYDEESK
                     ARTLVVGLTEKYPLYEEYNIMD"
     gene            33403..34500
                     /locus_tag="KRH23_002219"
     CDS             33403..34500
                     /locus_tag="KRH23_002219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016758 - hexosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009247 - glycolipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MGDG synthase family glycosyltransferase"
                     /protein_id="HHS5225497.1"
                     /translation="MKVLILTGKFGMGHYSASNSLSEDIKAKFDNSEIIIKDIFEYIM
                     PNYSDKMYKTFSILVNRGSSLYNLFYKCAENGKKDIKFTFSDYFLNKLDTLLHEVQPT
                     VVISTFPFCSQLVSRYKEKYNSNLPLITCITDISSHSEWISKNTDCYLVASKSTKEEL
                     VFKGIDESKIKVNGIPVKKEFKRIEHVNHSTKKNILIMGGGLGLLPKSEQFYKELNSL
                     KGVKTTVITGNNKKMYYKLYGRYENIEVVGYTNEVYKYMKDSDLIISKPGGITLFETI
                     YSELPILAFNPFLQQEIDNASFILNNEIGRILGKNKKYYVDEIKDLIYDDATLKEMSS
                     NMKELKKQFDNNTLENILFSLDEQGACRECM"
     gene            34491..35189
                     /locus_tag="KRH23_002220"
     CDS             34491..35189
                     /locus_tag="KRH23_002220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HHS5225498.1"
                     /translation="MYVVGLIIVVALIFLVHSIIPTYYNKLLNKEVLKNMAGENEIAL
                     TFDDGPDKRYTEKLLDVLKENDIQAMFFVVAKNAEKEPEIINRMLRENHIVGLHSLEH
                     RNAWLYSYSYVKKDFIESTNIMKNLGVDVNYYRPPWGHTNIFSNSFVKKYNLKMTLWD
                     VMAEDWEKDSTVDIIINKLMSRTKENSIICLHDAGENSGGAVGAPERTIEALKIAIPK
                     LKASGLKFVTPERM"
     gene            35192..36256
                     /locus_tag="KRH23_002221"
     CDS             35192..36256
                     /locus_tag="KRH23_002221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lysylphosphatidylglycerol synthase transmembrane
                     domain-containing protein"
                     /protein_id="HHS5225499.1"
                     /translation="MISKTEKKNKCLGSVAFLVLLMGITGYFVFRGQSVESLIKSLKG
                     ASPMFILIGFAMMFIYVACEGINIYLGMKALNQKTTLLKCMGYAFIGFYFSSITPSAS
                     GGQPAQVYYMKKDDINISYSSLILLVIVVIHQVVILAYSGIMFIMEREFILNNVSGMN
                     ILLIYGVITNVALVIGVIAIIFSKKLVNNFIISITNLLGKLRIIKDVESSRKVIISQI
                     EEYVKGAQYIKQNPKLVVQILVITIVQITAMFLVPFFVYKAFHLSTYTVFEILAIQSL
                     LNIAVSSLPLPGAVGASENSFMTLFKIFFPGHLLVPAMLLSRGISFYAFVAISGLICI
                     VVHVKSSEKVKAVKKVAYVR"
     gene            36439..37143
                     /locus_tag="KRH23_002222"
     CDS             36439..37143
                     /locus_tag="KRH23_002222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HHS5225500.1"
                     /translation="MNKEIPKKILVADDNPEIREIVEILLTGEGYEVIMATNGEEAVN
                     LVDSTIDLIILDVVMPVKTGFVACNEIREKTTAPILFLTAKTQDSDKVIGFSAGGDDY
                     LSKPFSYSELISRVKSLLRRYYIYQGKEKEREPNILKTKELCVNLDTQDVTLNGEPVF
                     LTTIEYSILILMLKNRKKVFSSENLYETIWDEQYFYTANNTIMVHIRNLRKKLEKDQK
                     NPQYIKTAWGKGYYID"
     gene            37136..38458
                     /locus_tag="KRH23_002223"
     CDS             37136..38458
                     /locus_tag="KRH23_002223"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="HHS5225501.1"
                     /translation="MINKIKPSKLGVILLIYVVISAAVAFILNIPFYSAVESIVKDVS
                     EGKVYFKREVNQLMDNFQTYVNNNGIRADDGDDIAKWNSDNWFVSMKIYKGNKVFYDT
                     LYYPNEVPDKSEENEFYSSPMARNYEIQFSDIKANIVVVALFRFRFQNFIEAISITFM
                     ALTFIITFLLLFSRKIKYLRKIEMGIKIVESGSLKYRIPVKGNDELSSLASSINEMSH
                     TLENQLIKEREMKNKNKDIVTSISHDVRTPLTSVICYLDLIKDHKYNSPEQLEQYIKN
                     VRSKAYQIKDLTDDLFTHFVNSGEEVSKGYEKINANEFIFQLLLDSSYTLEEKGFHIT
                     IENELYNQYHIYVDVTQFRRIFDNLCSNIIKYARKDKPIVFLIKVEDSKLLIIQKNRV
                     SNFSKNVESFGIGIKNCEKIVAYHNGSINVNSDDKEFAIEISIPAKES"
     gene            38645..40018
                     /locus_tag="KRH23_002224"
     CDS             38645..40018
                     /locus_tag="KRH23_002224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HHS5225502.1"
                     /translation="MVLTGAHYIYILFMVIILITMIMKKDTIVPCILGVFFMGLFFEK
                     NIFGAITAVFNSFIISLNELGPIILIIAIMVALSKALEANNAIQYMVRPFSRVIKNSN
                     TAFFVTGFVMLVLSWFFWPTPAVALVGAVFLPVAMRAGLPAIGVAVALNLFGHGLALS
                     TDFVIQGAPSITAGAAGVAVSYVINDGMILFWVMGIVTISMAFYTLKRDINKGMFREE
                     LKGFESEEVEEFNGKSKIATILVALGFLADIIAMYVFDLKGGDASALLGGTAVFLIII
                     INVINFGKDSLENVCENIIDGFVFGIKIFGAIIPIAAFFYMGEVAPLTGVFGKVLAPG
                     SQGLLSDIGIALSQTIPLNKFAVSGIETVVGAITGLDGSGFSGISLVGSLASVFGTAI
                     NASVGALAALGQISGIWVGGGCLVPWGLISAAAICGVSPIELAKRNFVPVITGLVVTT
                     IVAMFII"
     gene            complement(40378..41316)
                     /gene="pdaA"
                     /locus_tag="KRH23_002225"
     CDS             complement(40378..41316)
                     /gene="pdaA"
                     /locus_tag="KRH23_002225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="delta-lactam-biosynthetic de-N-acetylase"
                     /protein_id="HHS5225503.1"
                     /translation="MFRKVLHYLTLLSISIFFIVGCSNSQNNQNENQNKETQLQEDKE
                     KIDSGKDTSNVIVSDGTDKPSKATTNNDNNKLDVSSLDNTTLDWFYIPNNKHKTPEVN
                     TDIEFKFSDYDALYNGPTKDGQKTLYLTFDEGYENGYTTKILDTLKQNQVKAVFFVTA
                     PYIKENKDLVKRMVSEGHIVGNHSKTHPSMPTKTSNLKNFNDELYDVEKLYKDVTGKD
                     MVKFFRPPMGKYSEKSLAMTKNLGYKTVFWSFAYRDWDTDKQPSHEEATQKIMDNLHD
                     GSILLLHAVSKTSTEILNDFISNARKLGYEFELLEY"
BASE COUNT        16042 a         4716 c         7076 g        13759 t
ORIGIN      
        1 tgatatagta aataagaaaa aatttgaaaa aaatcactat aaatgagtaa taaatataaa
       61 tagtgtatac taatgggatg ggaaatgtcc actattaact ttattacccc acatatataa
      121 gataaaatta ttaatataaa atataatcta tcgacaatga atagactttt aaataaactt
      181 aatataaaat taattaaata agtgcttaaa aacgatttac tttaatgata gaatcatatt
      241 aaaggaggat aattttatgg atataaagaa taaaattaaa tctatatttt taccagaaaa
      301 aaatgactat ttagatgatg aagaatttga gtatgatata gaaaataatg aagaagattt
      361 aaaggaagat aacaaagtac atttaaatga tttaagcaga gtaaaatatg attacagaga
      421 gttaaaagac atagaaaacc aaacagaaga gatgtgtctg ctagcagtaa agcaggatgg
      481 tactataatt gagtttgtaa aggacaagac ttataaagta tgtatggaag cagtaaaaca
      541 gacatataaa gctcttaagt atataacaaa tcaaaatgag gatatttgta tagaagcagt
      601 aaaacagaac tacagagctt tgtactacat aaataataag acagaaaatg tactaattga
      661 ggctataaaa aatgcatcaa cttatgatgt catggaagta tttaaatttg tggaagagca
      721 aacagaagat gtatgtctag catttataga aagggcatct aaaaatgatg ttgcagagat
      781 attaaaagga ataaaagagc aaactccagc catatgttta gaagctgtaa aaaaagatgg
      841 aaaatcttta gcttatgtaa aggaacaaag taatagtata tgtttagaag ctgtaaaaga
      901 aaactacagt gcactatctt gtgtaaaaga gcaaactgaa gaaatatgta tagaagcagt
      961 aaaacagaat gactttgcat tgtattatgt aaatgaacag acagaaaaaa tatgtatgga
     1021 agcagtaaaa agaagttata tggctctaca gtatgtaaat aagcaaacag aagagatttg
     1081 tttggaagca gtaagaattg atggaagagc attacagtac gtaaaagagc aaacagaaga
     1141 aatttgcttg gagtcagtta gacaaaatgg aaaagtactg caatatgtaa aaaaacagac
     1201 tgaaaatata tgtatagaag cagtaagagg ttcatttgaa gaacttgaaa taaaagaaat
     1261 attaagttat gtaaagatac caacagaaag aatatttata gaagcagtaa agcaaaatgg
     1321 aaaaattctt aaatatgtag aaaatcagac agaattaata tgtttagagg cagtaagaga
     1381 aaactataat gctttagctt atgtaaagga acaaacagaa gagatttgtt tagaagcagt
     1441 taatcaaagt tatgaagcgc ttaaatatgt gaaagaacaa acagaagaag tttgtctaaa
     1501 agcagtaaaa caagattata gaatgttgaa atatgtaaat aatcaaacag aaaaaatatg
     1561 tttagaagca gtaaagcaaa attatagagc tttagaattt gttgataatc aaacagaaaa
     1621 agtttgtctt gaagcagtaa aacagaatag aaaagcacta cagtatgtaa aacaaaaaca
     1681 aagttaaaag gctaaaatat atagaaaata tatgcaaata aataaaattt gatattttgt
     1741 aataaataaa atgggtatct caaaatgaac tttttagttt gtgaggtact ctttttatat
     1801 gaaataaaat atatttttag ccttttaaca atggggaaaa ggtttatttc tattttgaca
     1861 taggcttttt atgcatataa agcttgataa aattgtttta ttataattgt tttgttatat
     1921 aaataataat aagaaaatta tataagtctt tttttgacca gttttacatt tttaacaact
     1981 agttttgtaa agtatattga attttctcaa aaaagaatgt attctatata tgtaaaattt
     2041 ttttggaggt aaaaatgttt aaaagatatg ctgaaaaaat gacatctgtt ttaatttgta
     2101 ataatatgat agataataat gaatctaaag tatattctta tggatttgaa atattaatag
     2161 ctttcatagt taatataacc accatgctgt ttataggttt tttatttggt aaatttacat
     2221 atgtattatt ttttttaatg tgttattgtc caataagaca attttcagga gggtatcatg
     2281 cagacaatta ttttagatgc ttattaacct ttatttttat aattttatct acaatcttaa
     2341 ttatagaaaa tataaatata gacttattta aaaatattat tatgattatt gcaagtgtta
     2401 gttgggttgg aatttgtgtt ctgtgcccaa tagaacatag gagtaaccct ataagtgata
     2461 gggaaaagtt ggtttataag aaaactgcta tatttatatc tacagtagtg ttattgataa
     2521 caattttaag tctttctttg agtatatttg tagattattt cacatatagc gcatttgcca
     2581 tgttttggat ttttgtgatg ttagtattag gtaagttaaa agctaaagta taagtaaaat
     2641 atgtatgagg gagagttaag ttatgaaaaa gtttattgta agatttatga agtttgctag
     2701 ctcattggca cttagcactg ctattttgtc agctaatagt acctgtcctt ggattattca
     2761 tcagcctaaa gtacccaaag aaatcagcaa tctaaagaag acaaattaaa tacaagcact
     2821 tatttataca aaattatcag gaaaaaagaa attattatat tttaataaga ttaaaacaat
     2881 ataaaaacag atacaaaatt tattttattt attttatagg agcctaatac ctatttggta
     2941 atatattagt gcgccaattt agggggatat agtgtattta atgaaatgac ttacggagag
     3001 taagtcattt ttgtattgta tgtattttat gtaaacttat gatataatga agggtaaagt
     3061 ttaattaaaa taataaaaaa ctttagtata gatagtaatt taggaggtag ggtatgagta
     3121 tgatacataa attttctatg aatggatata atatcgtttt agatgtgaat ggtggagctg
     3181 ttcatgtgtt agatgatgtt gcatacgatt tgttagattt ttataaagaa aaaagtaaag
     3241 aagaaatatt agagatatta aaatcaaaat atcaagaaga aaaaataaat gaagcatatg
     3301 aagaaatatt aaatttggaa aaagagggtc ttttatatac agaagataca tatcaatatc
     3361 atccaagctt tgtacataga gagcctgtag taaaagcttt atgtttaaat gtagctcatg
     3421 attgtaactt aaaatgtaaa tactgttttg cagctcaagg tgattttgga ggagaaaaag
     3481 aacttatgag ttttgaagtt ggtaaggcag caattgacta tttgattgct aattcaggaa
     3541 gtagaaagaa cctagagata gatttctttg gtggagagcc tttgatgaac tttgaagttg
     3601 taaaacaact ggttgactat ggaagaagtg tagaaaaaga ttataataaa aatataagat
     3661 ttacaataac tacaaatggt gtactgctaa atgatgagat tatagattat ataaatgaaa
     3721 atatgcataa tgtagtttta agtttagatg gaagaaaaga agttaatgat aatatgagac
     3781 caactttaaa tgataaagga agttatgata ttacattacc acgatttaag aaacttgtgg
     3841 aaaaaagagc aaaagataag tattattata taagaggtac ttttacaaga gataatttag
     3901 atttttcaaa agatgttatg cattttgcag atttaggatt taaattaacc tctgtggagc
     3961 cagtcgttgg agatgagagt aatccatatg cacttagaga agaagattta cctaagatat
     4021 ttgaagagta cgaaaaattt gctgtagagt atgcagatag acaattacaa ggagatggat
     4081 ttaaattttt ccattttatg atagacctaa atcaaggtcc atgtgtaata aagagaataa
     4141 ctggatgtgg agctggaaat gagtatcttt ctgtaactcc aaatggagat atctatccat
     4201 gtcatcaatt tgttggaaat gaagaattta aaatggcaaa tatatttgat gaagaaatag
     4261 tacttccaga aaatttaaaa aatatgttta gagaagctca tgtatatact aaagaagagt
     4321 gtaaacaatg ttggaataag ttttactgtt caggtggatg tcatgcaaat gcgataaact
     4381 ttaataatga catatcaaaa ccatatgaat taggatgtga aatgcaaaga aaacgtacag
     4441 agtgctctat aatgatacaa gctaagttaa tgttagaagg agcaaccaac taaatttata
     4501 ttttaaagga gttgtttata tatgattaga gattatttag aagataaacc tttaattgac
     4561 gaaagtgtat ttgtggcaaa atcagcagat gtaattggaa atgttaaaat aggcaaagat
     4621 tcaagtatat ggtacaatgc agtagttagg ggtgatgaag gaccaataac tattggagaa
     4681 aacactaata tacaagattg ttctatagtg catggagata cagaaactat aattggtaac
     4741 aatgtaacag ttgggcatag gtctatagtt catggttgta aaattagtga taatgtgtta
     4801 attggtatgg gttcaataat attggataat gctgaaatag gagaatatac tctgatagga
     4861 gcaggtacac taattacatc taataagaag tttccaccag gtgttttgat aatgggttct
     4921 cctggtaagg ttgttagaga gcttacagaa gaagataaaa aatatattga tgaatcttat
     4981 gaatggtatt tagaggcagc acaaaatcaa aaatattagt ttaaagagtg gttgtttcaa
     5041 aacatattta aatctgtttt gaggcaacca ctaatttatt ttattagatt ttgttgatat
     5101 tttagttttc aaaaagtatt tgattaaacc agatataaaa tgtcaaaaat aaaaattaac
     5161 tgagttaaat aattttaata aaattggtag tatatgtgat aaaattaaat attaaagagg
     5221 atataggata ttagaatatc aattggtgaa ataatgttat atacgataaa ttaaggtgta
     5281 agtttttggg tatacctatc ttaggagtga aaagatttga gaataagtta tagaaattta
     5341 aagcgatata gagaaattgg atatgtttta ataaagtatg gttttagttt tattgtagaa
     5401 agactaaata tagaaggaat tgcctataaa ataccactat ttgacccacc agaagaaata
     5461 aaaaatatga caactggtga gagaatgaaa agagttttag aagaactagg acctacatat
     5521 ataaaaatag gacagatatt gagtacaaga aaagacttgt tagaccagga tataattgat
     5581 gaaatatcaa aactcagaga tgatgtagag aaatttgatt caaatatagc tattgatata
     5641 tttaaagaag aagtgggttt aagtatagaa gaaatattct tagaatttaa agaagaacca
     5701 atagcagcag cttcaattgg tcaagtttat gaaggtgtac ttaaaacggg agaagaagta
     5761 atcgtaaaaa ttcaaagacc aaatatagag aaaataataa aatctgattt agagattctt
     5821 agaactattg caaatacttt aaaagattta aaaaaggatt ttaatttaga tttagtacag
     5881 atgattgaag aatttcaaac tcaattaatg agggaacttg attatacatt tgaagctata
     5941 aatgcaacta aattctctag gatatttaaa aatagtgatg aagtatatat acctaaagta
     6001 tactcagaat ataatactaa gaaaatttta gtaatggaga aagttaatgg tacaaagtta
     6061 agtgatgtag aaaaaataag gagactaggt tataacacaa aaactattgt tgaaatagga
     6121 gttaggtcat tttttacaca ggtattatct catggatttt ttcatgcaga cccacatcca
     6181 ggtaatatat tcgtagttgc taaaaataag atagcatata tagattttgg aatgattgga
     6241 attattgata ataaaacttt aaaccaatta aatgaaattg cattagcagg tgtagaaaag
     6301 aatgttgaca agataatata tctattgata gaaatggatg cattaaatgg agaggctgat
     6361 attaagggac ttagacagga tttactttat ctaatacatt attactatga tatttctata
     6421 gaaaaaataa atgtaacaga tatattaaat gaactattta ggttttttag acagtataaa
     6481 atagtcatgc ctgcacaatt tgtaactctt gcaaagacag ttataacatt agaaggaaca
     6541 agtagaactt taaacacaga tttttctttt ggttctatgg gaaaagagtt tatgaaacat
     6601 cattataaga gtaaatttaa ccctaaaaat gttgttttaa gttcaagaca aaatgtagaa
     6661 gaaatattac tggacataaa aactattcca aagcaattaa aagcaatttt aaaaaatata
     6721 gaaagaaata atataaaaat gcaaattgaa gatgttaaaa tgacgaggtt agaaaattgt
     6781 ataatagagc taacatctca aatatctttg agtttagtgt tggcatctat tatagtaggt
     6841 tcttctctta taattgcatc tccaaatata gaaaataata tatggataaa atttactgca
     6901 atagcgggtt tctttatatc ctttataata ggcctttgct tagttataag aagtattagg
     6961 tcaaaataca aaaaagatta gggggaatta aatttgaaaa aatggatatt gaagtataaa
     7021 ggtaagatag aggaaagtga atttagcaaa aaacttaata tttccccgga aatctgccaa
     7081 attttaaaaa atagagggat atgtactgaa aaagattcag aaatatttat gaatccatct
     7141 ttagattatt taagagaccc ttttttaatg aaagatatgc aaaaagctgt tgatagaata
     7201 aagttagcag ttgagaagaa cgaaaaaatt tggatttacg gagattatga tgttgatggt
     7261 gtatcatcta catctatctt gtgcttatat tttaagagta taggttacaa tgttgattac
     7321 tatattccta atagattaga agaagggtat ggtataaatg aagatgctat taagcttata
     7381 agctctaggg gatgtgactt gattataagt gttgactgtg gaattacatc agtgtctgag
     7441 gtcaatacag cgaatgattt gggcatagat gttataatta cagaccatca tgaatgtcaa
     7501 agtgaaattc catcagcctt tgcagtaata aatccaaaac aagaagattg taattatcca
     7561 tttgattcac tatgtggatg tggtgtagca tttaaaatga ttcaagcctt gactccaaaa
     7621 gaagaattta aaactagtat gtataattat ttggaaatag taacactagc aactatttgt
     7681 gatattgttc cacttataga tgaaaataga ataattgtaa aaaatggttt aaaatcaatg
     7741 aaagaaggca aaaatattgg attaagggag cttataaaag tttgtggtgt agaaagtgat
     7801 aagataggtt cttctcatat aggttttgca ataggtccta ggataaatgc ttcaggtcga
     7861 ttgggatatt cttacttagg agtagagcta tttactactc aatcacaaga agaggcagta
     7921 gaaatagcta gtatattgga agaaaaaaat aatgaaagac agatgataga agctaagatg
     7981 tatcatgaag ctgaagaaat gctaaagtct aatagcagat acaatgatga caaagtgttg
     8041 gttttagcta aagagggttg gcaacatgga ataataggaa ttgtagcatc aaagttaact
     8101 gaaaaatact acaaaccaac aattcttcta ggtatagaaa atggggaggc tactggttca
     8161 gcgaggtcaa taaaaggatt taatatattt gaagctctca taaagtgcaa agacttgatg
     8221 actaagtttg gtggtcatga acaagcagca gggttatcct tggattcaga caatgtagaa
     8281 attttagcaa atgaaataaa taaatttgca gattataatt taactgaaga tgatatgata
     8341 gagaatgtaa atgttgagtt tgaattacaa gaaaatgtaa taaatttaaa tcttgtagaa
     8401 gaattacata agttagaacc ctttggatta aataatccta atcctagatt tatagttaga
     8461 aattatattt taaaagattt gaaagttata ggtaagaatc aacaacatct gaaattaagc
     8521 atagaaaaag agaaaagcta tgaatgtata ggatttaata tgagtcattt aaaatcaatg
     8581 tataaagtag gagacaaggt agatgtacta ttccaattag atgaaaataa ctatatggga
     8641 aataggaaag tacaattttt acttaaagat atacgattgg ctcgacctaa aagtgcaagt
     8701 aatgacaaac tttcattgaa attaatgtca aaaataatac caaaagatac tcaaagcctg
     8761 tataatatat ctgtgtctga ttttgaatta tttgatggaa atacagatat aaatatattt
     8821 gattattttg aaaaagatac actaataata tctaattcta taaatggatt ttatagagca
     8881 atgtcagata tatcacttat agatttggat tttaacataa attacaatat tattgaagat
     8941 gttagcaaaa atactgataa attagagctt atattttctc ctaatattga taaaatagac
     9001 ttaaaaagat ataataatat tattctttat gattatttat acaataaagg cgaatattcg
     9061 tatatatatg agaataaaag agaagaaagt gaaattataa aatattataa taaaacagac
     9121 ctattatatt taaagaatgt agttagtaat atagttccat caagagatga atttataaca
     9181 atttataaac aagcactcat aaaaaaagaa attgatttgg atatggtaaa tataagggaa
     9241 acttttaatg taattccatt aaagtttttt acgatattaa atgtatttag agaattaaat
     9301 ttacttgact ttaatttaaa ttatgaaaaa aattctgtac tcataagaat attgccaaaa
     9361 ccacagaaaa aattagactt aaatgagagt ttaatactca ataatctaaa aaatttagaa
     9421 aaacaataca atagcagtta ttaggaggcg tttcccatgg atttaaaaaa ctttataagg
     9481 aatattgatg atttcccaaa gccaggcata gattttaaag atgtgacaac tctatttaaa
     9541 gatggagatg catttaaata tgcagtggat tctatagttg aagaattgaa agataaagat
     9601 gtagatttag taataggacc agaagcaaga ggatttttga tgggtacacc tgtagcatat
     9661 gctttaggag taggatttgt tccaattaga aaacctggaa agttaccagg tgaagttgag
     9721 agttatgagt atggattaga gtatggtaca gatactttag agatacataa ggatgcaatt
     9781 aaaaagggtc aaaaagtagc aatagtagat gatttattgg ctactggtgg aactatggaa
     9841 gccgctgcca agcttgtaga aaaattaggt ggagaagtag tttctatgca atttttgatt
     9901 gagctaaaat tcttaaatgg gagagaaaag ttgtctaact atgatgttaa ttctcttata
     9961 aaatactagt acttttataa tagttggtat aacaccaact attttcatat atattaaaat
    10021 tttatacaaa ataggtggtt atatgcatga taaagaatta caagaaataa ttgaaaaaat
    10081 aaaagtttat gcacctaatg caaattttga aatggttgaa aaagcctata atcttgcaaa
    10141 aaaagcgcat gaaggacaat atagaaaatc tggggaacca tactttattc atccattagc
    10201 agttgcaaat attttaatag agatggaatt agatattgaa actataacag caggtttact
    10261 tcatgatgtt gtagaagata cagaatatac ctatgaagac ataaaaaaag aatttggcaa
    10321 agaagtagcg gatttggttg atggagtaac taaacttggt caaataaaat atcgttcgaa
    10381 agaagaaact caatctgaaa atttaagaaa aatgtttttg gcaatggcga aggatataag
    10441 ggttatactt ataaaacttg ctgatagatt gcacaacatg agaacattaa aatacatgcc
    10501 tccagaaaaa gcaaagtata aagcaaaaga gacacttgaa atttatggtg gtatagctca
    10561 tagattagga atttccaaga taaagtggga actagaagac agagcattaa gatttatgga
    10621 cccagaaggg tattatgatt tagttagtag agtatcaatg aagagaagtc aaagagagga
    10681 ttatattcaa ggaattgttg aacttcttaa agataagttt aaagatttaa gtataccatg
    10741 tgatgtatat ggtagaccaa agcattttta cagtatatat agaaagatgc aaaaaaaaca
    10801 taagactttt gaagagattt ttgatttaac agcagtaagg atattggttg ataatgtaaa
    10861 ggattgctat gcagtacttg gtatagttca tacattatgg agacctattc caggaagatt
    10921 taaagattat atagcaatgc caaaacccaa tatgtatcaa tcattacaca ccactgttgt
    10981 aggtcctgat ggagaacctt tagagataca aataagaact catgagatgc ataatatagc
    11041 tgaaaatggt atagcagccc attggaaata taaagaaggt atctctagca aagaatcaaa
    11101 ggttgaagaa aaacttcaat ggttgagaca gatgatggag tgggaaaaag atttaaaaga
    11161 cccacaagag tttatggatg cacttaaaga agatgtattt aatagtcaag tttatgtatt
    11221 tacgccaaaa ggagacgtaa ttgaattacc agcagaatca acacctatag attttgccta
    11281 tagagttcat acaaatgtag gtaataaatg tgtaggagct aaaattgatg gaagaatagt
    11341 tcctattgat tataagcttc aaaatggtaa tattgtcgag gtacttacat catctaattc
    11401 taatggacca agtagggatt ggcttaatat agtgaagacc ccaaatgcaa aaagtagaat
    11461 tagacaattt ttcaagaagg aaagaagaga agaaaatgtt gaccgtggaa atacaatatt
    11521 agaaagagaa tttaagaagc atgatatacc acaaaaagac cctcttgttg aaaaatatat
    11581 ggcattagtt gctaagaaat ttaatcagcc aagtgttgag gacttaattg ccactgtagg
    11641 ttatggtggt ataatgtcat ctcaagtggt atctaaggta aaagacctat atttaaaaga
    11701 ggttaaaaaa gctaaaaagg aacaacagat acaagaagaa gatttaaata aacacaatat
    11761 aagtgaaaca gaatacagta aaaagagaaa gaaaaacgca tcacaaggaa ttatagtaaa
    11821 agggcttgac aatatcttag taagatttgc taagtgttgt aatcctcttc caggagatga
    11881 aattgtagga tatattacta agggtagggg agtagccata cacagagctg attgcccaaa
    11941 tgcaaacaat aatggtgatt tcttccaaaa tagattggtg gaggtttcat ggagttcagc
    12001 aggaaaaggt aagtttgaag cggaaattca aataaaagct attgatagaa gaggaattgt
    12061 taatgaaata actcatattg ttgcaatgga taaacttagt ttaaacggaa taaatgcaag
    12121 aaaaggtaag gatagtattg taagtataaa cttacttgta gaggttaatg acacagagga
    12181 attaaaaatt ctaatgaaaa aattaaaagc aattcctggt gtagaaagta tttatagaat
    12241 gacaaattag agttaaaata atagggagga aactatgaga gcagtagtgc aaagagtatc
    12301 ttcatctaaa gttacagtag atgaaaacac tataggtcaa ataaataagg ggttactagt
    12361 attgttagga gtgactcatg atgataaatc aagtgatgta gattatatga ttgataaaat
    12421 attgaatctg agaatttttg aagatgaaaa tgacaagatg aatttatctc taatggatat
    12481 aggtggagag cttttagtag tatctcaatt tactttatat ggagattgca gaaaaggaag
    12541 aagacctgga tttagtaatg cagctaggcc agaacttgca aataaccttt atgaagaatt
    12601 tgtaaaaaaa gcaaaagata aaggtgtgac agttggtaca ggtcaatttg cagctcatat
    12661 gatggtagag ttaactaatg atggtccagt aacaatacta ttagactcaa gtaaatcttt
    12721 ttaaggggga aaactttaat gattataaaa aaatttgtag atagttattt tggagtaaat
    12781 acttatgtat taggtgatga aaagactaaa aaatgtgcag ttatagaccc aggtggaagt
    12841 ttagtagaga cattaagttt tgtaaaagaa aatgaattaa atattgaata tattatcctt
    12901 actcatgggc atggagacca tataggatat gttaaggata ttaaagaaaa aacttgtgct
    12961 aaagtagttg cacatgttga tgaaaaagaa ttattaaatg ataaaaataa aaatctaagt
    13021 tatacaatga gatgtggagc gcaagagttt gatgcagata tctatgtgaa tgataaagac
    13081 aagcttgaac ttggtgaatt aaaaatgact ttcttgcata ctccaggaca tactcaagga
    13141 tgtatgtgta taagagttga agatgaaatg ttcacaggag atactttgtt tgctggaagt
    13201 attggtagaa ctgatttata tagtggggat tttaaccaaa tggaaaaatc acttaagaaa
    13261 ttatgcaaat atgaagatgc tgttagagta tatcctggac atggaccaac cagtactcta
    13321 ggggttgaaa agaagacaaa tccttacatg taattttata ttagtattta aaaaagtata
    13381 aaatatttaa taactatatt agtgaggggg ttcttctact gttaaataga aggagttaag
    13441 ttgatgttgt atgttttttt aaaaggacat gattataagt atgaagtagc agaacttata
    13501 aaattgttta ccagtgaatt taagtttaaa gactctaatg ctaacaataa tatagagtca
    13561 aagcatttaa taaatagatt gatttatgag aatggtgtat tattctcaag tactgaatac
    13621 tatgaaaatg gaaacttaaa gtatgagtca atacagaata taaaaaatat gaatcttgaa
    13681 tttttagatg gatttgatag tagcaaaacg attgaagaat ttcttaatag cctagatagt
    13741 gaaagtaaga ggaactttaa aaagctgtgt aaagaaaata tcaaaaaaag catgttttta
    13801 gtgcttaaac aagtatttaa ttcttatgta ccatggggaa ttttgactgg tattagacca
    13861 gtcaaaattg tccacaattt aatggataaa aagctagatg ataatagcat aagaaccatt
    13921 ctaaaagata attattttat aatagatgag aaaatagatt tagctcttga aatagctaaa
    13981 agagagcgat tatttatgta tcctatagat aaaaataaaa tttctcttta tgtaagtatt
    14041 ccattttgtc caactaggtg tgtatattgt tcatttcctt caaattcatt aaaacaattt
    14101 ggacatttaa aaagagaata tgtttataaa ttgattgaag aaattaaggg gtttgccaaa
    14161 gttattaagg agactaagaa agaagttgaa actctatata ttggtggtgg aactccaact
    14221 acacttgatg aggaagaatt ggatttgctt ataaattcat tgttcaatga attagattta
    14281 agtaaaatta aagaatttac tgtagaagca ggtagacctg acactattac agaacaaaaa
    14341 ctaagagtgt taaaaaaaca caatgttagt agaattagta taaatcctca aactatgaat
    14401 gatgatacct tggtaaagat tggaagagag catagagtat ctgatttagt agattgcttt
    14461 aatatggctc gtagaatggg atttgataat ataaatatgg atataatttt gggtcttata
    14521 gatgaagatt taaatatggt aaagaataca ttggaggaga taaaaaaact ttctcctgaa
    14581 agccttacag ttcatacatt agccataaag agagcatcca acttaaatat aaatatggat
    14641 aggtataaag aacatctaac acaatatgaa gaaatggtaa aaatgataga tttatcaatg
    14701 aaatatgcaa aagatatggg attaaatcca tattatatgt acagacaaaa acatatgttg
    14761 ggaaatttag aaaatatagg ttatgctaaa gaaggatatg agtgcattta taatatacag
    14821 attatggaag aaaaacaaag taactatgca ttaggtgcag gtgctatatc gaaatttgtt
    14881 tatgtagatg aagatagaat tgaaagagta gaaaatgtaa aaaatgttga acaatacatt
    14941 gaaagagtag atgaaatgat aaaaaggaag aaagaagagg tatataaaaa tgttgactaa
    15001 agctcctaga ggaactaaag acataactcc aaaagaggct tacaaatggc gttatgtaga
    15061 aaataaattt agagaaatat gtgctttata tggatatgaa gaaatggtaa cacctatatt
    15121 tgaacataca gaacttttca agagaagtgt tggagatact acagatatag ttcaaaaaga
    15181 aatgtattct tttaaagata aaggtgatag agaaattacc ctaaagccag aaggtacagc
    15241 aggtgtagta agagcattta tagaaaataa attatatgca gatactcaac caacaaaatt
    15301 attttatgtg acaccttgtt ttagatatga aagaccacaa gctggtagac aaagacaatt
    15361 tcaccaattt ggaatagaag cacttggaag tgatactcct tcaatggatg ctgaaataat
    15421 cgcactagct gttcaatttt ttaatgaagt tggattaaat gatttggtag tgagtataaa
    15481 ttcagttggc tgtccagttt gtagaaaaga gtacaatgct ttattaaaag agtatcttga
    15541 ctcaaaagtt gatatattgt gtgatacttg caatgagaga agagaaaaaa atccaatgag
    15601 ggttatagac tgtaaaaatc ctacatgtaa agaaaatatc aaagatatac catttattgc
    15661 agaccatttg tgtgatgatt gtaaatctca ctttgataaa cttcaagaat acttaaagga
    15721 aatgaatata aactttgtaa ttgataaaac aatagttaga ggcttagatt actatagaaa
    15781 aactgctttt gaaattatat ctaatgatat aggagctcaa agtactgtat gtggtggagg
    15841 aagatatgat ggtcttgttg aacaattagg aggaccaaaa ggtataagtg gaattgggtt
    15901 tggactagga attgaaagac ttttacttac acttgaaggt aatggaattg aaatagaaaa
    15961 ccctcaatct acggatatat ttatagtaac tataggtgaa gaagcaaata caagaagctt
    16021 taaattgtta aaagacttga gacaaaatca tataagtgca gataaagacc atatagagag
    16081 aagtgttaaa gcacaattta aatattcaga taaaataaat tcaaaattta caatagtaat
    16141 tggagatgat gaacttaaaa atgacactgc gacattaaaa aatatgaaaa catcagagca
    16201 aactactgta aaattaagta cattagttga agaattaaag caaaagctgt aaaataagaa
    16261 agtatgatgt tttgtgtatt agataaatat atagcattaa aattaaataa aatggaggta
    16321 gtatcttgga aactttaaag ggtttaaaga gaactcacta ctgtggagag ttgagagaaa
    16381 aaaacataaa tgaagaagtt gtacttatgg gatgggtaca gaaaaaaaga aatttaggtg
    16441 gtcttgtatt tgttgattta agagatacaa gtggattatg tcaaatagtt tttgatacag
    16501 atgtagataa agaagctttt gaaaaagctg aaaaattagg ggctgaattt gtaatagctg
    16561 taaaaggaaa agtatgcgaa agacaatcta aaaaccctaa tatgccaact ggtgatatag
    16621 aaatatttgc aactgaactt agacttttaa acaagtcaga aactccgcct atttatataa
    16681 aagatgatga tgatgtttct gaagcactaa gattaaaata tagatactta gatttaagaa
    16741 aaccatctat gcaaagaaat ttaaaattaa gacataaagt aatgaatatt acaagaaatt
    16801 acttatcaaa caatagattt tgcgaaatag aaacaccatt tttaatagct ccaacaccag
    16861 aaggagcaag agattatcta gtaccaagta gagttaatcc aggaaaattt tacgcattac
    16921 cacaatcacc acaattatat aaacaattat tgatggtaag tggtatggat agatatttcc
    16981 aaatagttaa atgctttaga gatgaagatt taagagcaga taggcaacca gagtttacac
    17041 aaatagactg tgaaatgtct tttgttgagc aagaagatgt tatgagtatg attgaaggtt
    17101 tgcttgaagc gatatttaaa gaagttttag atgtagaatt ggcacttcca cttcctaaga
    17161 tgacttatgc agaagctatg tctaaatatg gttcagataa accagatact agatttggat
    17221 atgagttaac agatatatct gatgttgttt gtaactgtgg atttaaagtg tttgctgatg
    17281 ctacacaacc aggaaaaagt gttagaggta taaacgtaaa aggcaaagct gacgacttta
    17341 ctagaaaaca aatatcatca ctagaagaac atgctaagac atatagagca aaaggtcttg
    17401 cttggatgaa agtaggacaa gaaggagtaa cttctccaat agcaaaattc tttaatgaag
    17461 aagaaatgaa cgctatactt acaagaatga atgctgaagt aggagattta cttttatttg
    17521 tagctgataa aaactcaata gtatttgatg ctttaggaca agttagactt gaagtagcaa
    17581 ataggcttaa tctattggat aaaaatgtat ataacttact atgggtaact gagttcccag
    17641 tttttgaaga agatgaagaa acaggcacat tctcagcaat gcatcaccca tttacatcac
    17701 ctatggatga agatttagac aagttagaag aaggtgataa gtcatcttta agagcgaaag
    17761 cttatgatat tgtattgaat ggttatgaaa taggtggagg aagtgttaga atatcaaatt
    17821 ctgatgttca atcaagaatg tttaaagcac ttggttttac agaggaaaga gctaatgaaa
    17881 agtttggtta tttattagaa gcatttaaat atggtactcc tcctcatgct ggtctagctt
    17941 ttggtcttga tagacttgtt atgttacttg caggaactga taatataaga gaagttattg
    18001 cattccctaa aaatcaaaat gctgtttgcc ctatgacaaa tgctcctaca ttggcggaag
    18061 atgagcaatt agaagaatta agtataaaag ttgatataaa agataatgaa taatatgtag
    18121 ttgcaggaaa ttaaaatgta aaaagtctgg atataaagta tatttatatt cagacttttt
    18181 ttattagaat tattttatat tttttctcta tatattttca taaattatcc ttatattctc
    18241 agccaatata attaaaatac tatgtttaaa aattttacat aaacttgatt attttagaaa
    18301 ctacttctgt aatgagtaca cgattttaat taaagaatat ataacaaatt tgaaataagt
    18361 ctaatatatg acttaataga ttaaattaaa ataataaatt tggactattt atctatttat
    18421 aacttaaatt atatcaaatt gataacaaac tagatattat acttttttgt agaatagaat
    18481 tacaattata taaagaaaaa ttctattaat agtgaaaaaa aagtagaaaa aagtagaaat
    18541 tattctttta taaagaaagg gagggataat attgcaagag agagaagaat tagttttaaa
    18601 tccagttcca aaagaggaaa gagttggatg gttagctcca ttgtttaata tgcttggttc
    18661 taacatagct atatctgaac taatggttgg gggaacttta attttaggaa tgactctttc
    18721 taatatgatt attacatcaa ttatagggaa cttaatatta gttgcaatta ttatgataca
    18781 aggttatata ggttacaaag aagggttaaa tacgtatgta ttagctaagg gggcatttgg
    18841 agagatagga ggaaagtatc ttatatctct attacttggt ataactagtt ttggatggtt
    18901 tggtgtacaa gcaggggttg caggactatc agtacaaaag atattcccaa gtgtaaacct
    18961 aacattagtt acagttatac ttggattatt tatggttgtt tttgcactgt atggctttaa
    19021 agctatggct aaatttaatt acttagttat accaccactt atgatattaa tggtgtgggg
    19081 agtttttaaa gctttttcta cttatggagt tgaagctatc tataattata ctcctcaaac
    19141 aactatgagt atggttgaag gtcttaatat tgtagtaggt cttgttatag ttggtgcaat
    19201 tatatcacct gaccagttaa gatatacgag acgagtaaaa gatatttgga ttatcagttt
    19261 tttaggtcta gggattattt cattattcca acaagttgca gctggtgtaa tgtctatggg
    19321 agcacctact tgggatataa cagaagtatt ggctaattta ggttttggat gggtagcgtt
    19381 tgttatttta atacttgcat cttggtctac aaacgtatca aatgcttatt ctggtggatt
    19441 agcattaaaa actatttttc caaatgtaaa aagaaatgtt ttgactttag ttgcaggtct
    19501 aataggtaca ataatagcag ctactggtat aatatttaaa tttcagtcat ttttatcttt
    19561 cttgggaatc gcagttcctg caatagcagg aattatgtgg tgtgagtatt attttataca
    19621 aggaagaact tataagcata gagaaggaat aaattggatt gcagtaataa gctggttaat
    19681 aggttttgca gcgtcgtatt atagttcaaa aataaatttc ttaatacctc cgataaatgg
    19741 aattgtagtg agtatggtta tttattatat attaatgaaa tgttttggaa tcaaagataa
    19801 ataaaggggg caattacatg ggtcgtaagg tgaaaatagg tataattcaa caacacagtg
    19861 tacttggaaa tgttaaaaaa aatatagaaa aggcagtaga gatgatagat gacttaggaa
    19921 aacaaggggc agatataatt tgtttaccag aactatttgc tacaggatat aatttagagt
    19981 ctttaggtgg agttaaaaca ttagaattaa taagagaaca taataagtac atagaggaat
    20041 caatgtcaga agccgctaaa agaaataatg tatacctgat atctccatat ggaaccttag
    20101 aaaaagggtc tacacatgtt tataattcag cagttatatt tgatagaaaa ggtaagatta
    20161 tgggagaata ctgtaaaaat catctgtggt cattagaagc agtatacttt aaaggagggg
    20221 aaaaagtaga ggtatatgat gctgattttg gtagatttgg tgtaatgata tgttatgatg
    20281 caggttttcc agaagtatcc agagaattga cattaaaagg ttctgaaata atatttatac
    20341 catctgcatg gagaatacaa gatgaagata tgtgggattt aaatgtatct caaagagctt
    20401 tagagaacac tgtatataca gtaggtgtaa atttagtaag taatgactct aatttaatac
    20461 tatttggaaa gagtaaaata tgcaatccta gaggtacggt aataactcaa ttagatacat
    20521 acagggaaaa atatgtatta tcagagattg atttagatga aataaaaaag tatagggaag
    20581 atatccccta tttgaaagac agaaaaagta gctataacat ataattctat actataatac
    20641 aagttcaata taaaatgata aaaagaggat gtatcaatat taagattaaa tttattatac
    20701 tttgatatat cctctttaat attatcaact ttgatttaaa tatttttaaa atagttgata
    20761 agaaagtttt tgaacaacaa cacagcttta gattcatagt tttcgctaaa ccatgaaaga
    20821 tttaaatatc ttttaaattc aatatctttg atatgtaaca acttaatctc agggtcttga
    20881 gataatcccc atgattttcc acatataaat ccaactcctt gaagtgattt tataagagca
    20941 taaattgtat atggtgaatc agactcaaat gctattttgg gtttgaaatt agctgattcg
    21001 cacaggatat caattacctc tctataattc tcacccttcg ttataactat aaagttttca
    21061 tctgaaactt cgcttagata tacttcatcc tttaatgata aaggatgatt tattgaaact
    21121 cctaatagta tttcttcgca tgttaaagtt atgctatttt ctgagtttag ctttgtaaat
    21181 gaagaagata tgtacaaatc aaaatcactt tttttataag atgatggcaa agtatgtgac
    21241 acattaaaag taatattggg atatagtttt ctgaaattac tcaaaagtga tggtaacaca
    21301 ttagccgctg caggagataa tatctttact tctcctgaat tttctaaaga agtgtcttgt
    21361 aactcctttt ttgaactttc tactaaatct aaaatgctat ctactctttt tagaaacaat
    21421 cttccatact catttaaaac aatatatctt ccttttctgt caaataactg aactccaagt
    21481 tctttttcta aggaagatat agttttgctt aaagctggct gtgctatatt taacttgtgt
    21541 gatgcttttg ttatgtgctc cattctagca acagtttgaa aatacttaag atgcaataaa
    21601 tccatagtat aaaatacacc tcttttaata tgacttgagt tatatcaatt ttataatcaa
    21661 ctccacatta tacattataa tataaagttt atataataaa ccacaatata ttaaaaagtt
    21721 atttaaattg ttatttatat tttgtacata atctaattaa aaaaagtaac tttaaatgat
    21781 taactaagga aatgttgtta caaactttag ttatataaaa aattcatttg atgagcaaag
    21841 tactaatatc aagtaagaat aaaagcttat tagataagaa aaataatatt ttataataat
    21901 gatgttactt aaattattat gttatactat tttaaatagg aaacatttag atactataat
    21961 tttaggggga gtcaagatga aattaactaa atcaatatca tcaatgctgt gcttatctct
    22021 agttttaagc ttatcaccag tagcatatgc aaatgaaata agtagaacaa cagttgagaa
    22081 tactttagta ggtcaggata gatatcaaac tgctgttgaa gtaagtaaaa aaggatggag
    22141 tagtgcaaat gaggctgtag ttgtaaatag tgaatctatt gtagatgcat tagctgtaac
    22201 atcatttgct aaattaaaaa atgctcctat attattgaca gaaaaaaata atctaaattc
    22261 acaaactgag aaagaattaa aaagattagg agttaaaaaa gtttatataa ttggtctatc
    22321 tagttctgta tcaaatgatg tgcaaaaaca gttagaatct aataatttaa ctactgatag
    22381 agttggtggt agtgatagat accaaacagc tttgagtata gctaaaaaaa tagaaggatt
    22441 aaaagatata tcagaaatag ctgtagtaaa tgggtacaca ggtcttgcag atgcagttag
    22501 tatagcttct gtagctgcta ctaatggaat ggttatactt ccagtatctg atgcatctgg
    22561 tatatctagc tttaaagatt ttatagaatc taagaatata aataaatcat acataatagg
    22621 ctctactaat gctgtatcag ataaaataaa acaaagttta cctaattcag aaagaatagg
    22681 tggagcagat agaaatgaaa ctaatggtaa agtaatagaa aagttttata catctaataa
    22741 attaaacaat gtatttgtgg ctaaggatgg aatgaaaaat caaaatcaac ttatagacgc
    22801 tctagcagta ggagtactag catcaaaaga aaattctcct gtactaatcg taggagaaca
    22861 attaagtgca acacaaaaga gtgtattttc gaataaaaat gctacctcta taactcaagt
    22921 tggtagtgga ggaaatgaaa atgcatttaa agaattaaaa gatttacagg caaatagtaa
    22981 caataagaga gtaatgtatg taactaatac agataaggta aatataagaa atgatgctac
    23041 aatagaagct tctgttatag gatatctaaa taatggtgat gaagtagaag ttttagatgt
    23101 gttaaaaact ggatgggtaa aaataaaata caatgaaggt attggatatg ttagtgggtc
    23161 ttatttgaca aataataagc ctgataatag taatgaaaat ataaaaataa agtatgtaaa
    23221 agaaaaagat ggtctaaatg ttaggaaagg accaagtaca gaagatgaaa aaataggtca
    23281 cctttcatat ggaagcaaag tagaaacaat agaaatgttt gctactggat gggtaaaaat
    23341 aaagtataat ggtggatatg gttatgtaag taatgattac ttatctgata caccagttat
    23401 ttaattataa gtaacaataa aaaactgctt taatttgtaa agcagttttt ttataaaaat
    23461 ttaagtctaa taactatttc tattttgata ccttaatcct gggatttatt attatggata
    23521 ttatcaacat acaaacactc caaatccagt gtctaattcc aaacttagat attaataaat
    23581 tcagtcctgc tatggtaaat aagcagtatt taattacaat taaaagtgta tttctagaaa
    23641 gccccttcat agaaagtatc ctaaatccaa taatagacat tctaagtcct ataaatgcca
    23701 ataatatacc tgcaatatcc tgaattaagt aatagtattc aaatttcata ttcaatcaac
    23761 tcttctctga gcagtatcaa atatttctaa ctcttcaatt tcatcatctg tgtatgtaag
    23821 catagtaaaa ccagttacac cataaataaa tgaaattata ggtgtaatcc aacttaagaa
    23881 acaatatgga ataaattcta gtgggcttac accaagagtc tgagcacaga aaacagcatt
    23941 tgaattccat ggtattaatg ggccaccaag tgtagctgta tcttctataa ttctagatag
    24001 attttgtggt tttaatttaa attctttgta tattggagac attagagttc caacaaatac
    24061 agaagtgaac atcattgatg aactaaatgc atttgcaaag tagcttacta taaaagtaga
    24121 cccaaccaat ttagttcttg attttcctat tttagttata agaggttgaa gcagtacttc
    24181 taagaatcca gttttttgga gaataccagc aataacgaaa actacaaata ctagtaaaac
    24241 ggtttcagcc atactcatta ttccaccacg atttaatagt ttgtcggcat agacaaatcc
    24301 agtatctata gtaaatcctg atagcatgta atttaaaaca tcacctattt tttctccttc
    24361 ttgaaatact gctataataa gtcccatgat agctgaactt agtatagata taatgggtgg
    24421 cttttgtagc aataaaagta ataataaaaa tattattgga atcattgcta ctaaaccaat
    24481 atgaaagttt gaatttaata catccttgat ttgatttatt tgaacatagt ctatagtatt
    24541 atttgaatac ttaaatccaa ttactgtata cagaactata catattacgt atgcaggtcc
    24601 tgtggtataa aacatatgct tcatatgtgt aattacatct gtcttacaaa ctgctgcagc
    24661 taagtttgta gaatctgata gaggtgacat cttatctcca aagaaagcac cagaaatgac
    24721 tgcaccagct gttaaaccaa gaggaatacc catactagta ccaatactca tcattgctat
    24781 accagaagtt ccaagagtcc cccaagatgt accagtagca acagaagtta atgaacatac
    24841 gattaatgtt gtaagcagaa aatatttagg ggttattatt gttagtccac tatatactac
    24901 tgttggtatt gtaccagcag ctatccaagc tgctattagt acaccaacag aaagtataat
    24961 taagtttgat tgaaaggcat ctttaccaac ttcaaatcca aaagcttcta tttcatcatt
    25021 agtataacca agtttcatgg ctgcaggaac tactataagc catgaaagta aaaacattgt
    25081 agttatagaa gcattaaata caactatacc aactgatgtt agagctatta ttgcaagcat
    25141 tactaacaag gaatatctaa atgaaggtat ttttctttct gtattcattt tcatagtgca
    25201 aattctcctt aaatattttt agttaattgc attttttatt cttataagag cttcttcaag
    25261 catacttctt ggacaagcta agtttattct ttgataccca cttcctccaa tgccaaagct
    25321 gtttccttga tttagagcaa ctttaccttt ttgtacaagt atactttcta gttcctcatc
    25381 acttaatcca agtgcactaa agtctaccca taataaataa gtaccttctg gttttctaac
    25441 tttaagtttt ggcatatttt catttatata ttttatagca aaatctatat tagattctaa
    25501 atattctaaa aatgattcta gccaagattc accattatta tatgaagctt cagttgcaac
    25561 taagctaaag caattatttc tctttatatc aattctggta aaggcatcat ctaacaattt
    25621 atagtctttt tcatcaggta gtactacata tgatgattga agaccagcta tattaaaagt
    25681 tttagttgga gccatacaag taattgtatt tttttcaaat tctttagaaa tagatgccat
    25741 aggaatatgc ttatgttttt ttaatataat gtcactatgt atttcatcag atatgatttt
    25801 tacattatgc ttaagacaaa tatctcctag tttttttaat tcatcttttg tccatactct
    25861 accaactgga ttatgaggat tacaaagtat gaataatttt acatctttaa tcttgttttc
    25921 aatgtcttca taatccatta tgtagtttcc attttctaat ttttgtaatg ggcttataat
    25981 tagttctcta ttgttatttt ttacaacact attaaaaggg ctgtaaactg gttcttgtat
    26041 cattatttta tcatttgctt ttgtgagttc atttattaaa agacttatag ctgggataac
    26101 acctggacta taaattaacc actcactttt tattttccag ttatgtctcc tatctagcca
    26161 gtttactata gattcattgt aagaatctgg tcttgttgtg tagccataaa tctcttgttc
    26221 tagtctattt tttaaagaat caattataca aggtgcagcc ttaaaatcca tgtcagccac
    26281 ccacatagga agtaaatcat tagttccata ctttttttcc atttctgacc atttagatga
    26341 aaaattattg cttctatcaa caatctcatt aaaattataa ttcattgtaa atacctccag
    26401 taattttaat tttatgttaa taatattaag caaacaacgt gccaatattg ataataaaaa
    26461 atatttattc acaagttaat atttaatatt aagtaatttc agagcataga taagataaaa
    26521 atattaatta tacttaaaac tttgtggaaa aggttatttc taataaattt ttaaatatat
    26581 gaaaatgtaa ttaaataggt taaataggtt taactattta acttgttaga cctatttata
    26641 ttttttagaa attctactcc ttttgatgtt ataattgaac ctccacgacc aacaagtatg
    26701 tctacaagcc caaagttttg tagttctaaa agcatatttc taatctgttg ttctgtcaaa
    26761 aatctatttt cctctaaagc tattttacat aagctttttc tacctattct ttcttttaaa
    26821 tcataagcct tttttaaatt atccaatata aatatgtatt catctagtga ccttttaaaa
    26881 ttatagtcgt atttcatgat gtttttgtct ttgccaatgt tgaattgata cttttttata
    26941 ttatcactta ctttattaca aacggttcta ctataatttg aatctatagt atccaatata
    27001 tattcaggta aatcacatat ttctataata tctttttcca agtaacagaa gtattctcct
    27061 aagtttctta attctcttac atttccttcc catctataca ttttaaagat ttcttttact
    27121 tcctcactta gaataaaatt acatggaata tcatatttta atgaaccaaa aatttcaaat
    27181 atatcagcag gtctttccct aagtggatgt attttaaggg gaagaacatt caacctaaaa
    27241 tataaatctc ttctaaacat atttttagat acaagttctt ttaaatttct attagtagct
    27301 gcaattattc ttacatcaat gtcaatgaca ttattagaac caatacgtcg tacttgtttt
    27361 tcttgtatga ctctaagtaa tttagattga gaatttaaat ccatttctcc aatttcgtct
    27421 aaaaatatag ttccattgtt ggctaattca aataaaccaa ttttcccacc ttttttagca
    27481 ccagtaaaag ccccttcatc atagccaaat aattcacttt gcagtagatt ttcttgaaaa
    27541 gtactacaat ttactgcgac aaaaggacca tcttttctcc tagaagcact atgaatggat
    27601 tgagcaaata attctttacc agtaccactt tcaccaatta taaggataga tgaatttgat
    27661 tgagccattt tattagcaat tttttttgta ttaatagttt gtatactaga acctaatata
    27721 tcatcaaatg tgtatttact gatattacca gagtttacta gttgtgctct taatttagct
    27781 tgcttttttt ctaattgaga aaactttgtc atctttagta taaatccatc aaatacattt
    27841 aattgtatat gtttaatctc taaatttata tcaatatgat ttattttaat caatttctca
    27901 aaaaatggag ttttattggt caatatgctt tgaaaattga tgtcttttat gcaatcacca
    27961 acaaatgagt caatcatttc atttgcattt atagacaaaa tttttctagc catatgatta
    28021 tagaattgaa ttattccatc gttatttgtg catataattc catcatcaat tatagatagt
    28081 aacaaatcaa attgtctttc aaacttattt gcatctaaca ataactcacc tgtactataa
    28141 cttgtaggaa ttattttttc tacgtatttt tttattaggt catcttttat tagatgtttt
    28201 aatttggttt ttgtagcaat ttcaacaata caacttaaat ctattattct gtattttaaa
    28261 tctataactt cacaattttt aaacttaggc aagatttttt cgccaggagt taggattaca
    28321 gcatctgtgg gagtaaactc aatctctgga tagcagggca gtatatttat attgtctatt
    28381 cctaatctat gtattaaaga aattgtttct attgccatat ctttacttaa gttatataca
    28441 taaataattt tatctttttc taatttggat atcatatcaa tactgttctt ttcaaatgtc
    28501 aacttgggaa caatgatttg agcatcagag tgagataatt ttactatttc atcatatttt
    28561 aaataagcag ataggagtat aagtttttct ttaaaaaact ttaaatttcc ctcttcaaat
    28621 gagtataaat ttatctttag attatcacct aagaattgcc ttatttgatt ttcataaatt
    28681 tctccagcgt ctttttttaa acttacaata gctaattcca tttgtttcat tttaacctct
    28741 catacaaatt tgacttattt tagattacat aataattaaa ttagattaaa taatattatt
    28801 taattattat tataaattta ttatagacta cacattgaag taaaagaagt agctaaaatt
    28861 attcctttta tttttgtttt ttgtatctat ttggtataat agtattagag cgtataataa
    28921 tttaggcaaa attttttaag gaagactaga ggagaatata aaatgaaaaa atgtctttac
    28981 tgtaataggg atataaagtc accaaataat aaattagcta taaaatatga tgacaatatg
    29041 aatatatatc catgtcgtgc agaatgtaag gaaaaaattg aagaatatat agcaaaaaaa
    29101 cctacatata agtttataaa tatattagag gttcttttag gtgtgggcgg aatattctgc
    29161 tttttgagta aatggactat tgcagcacaa gttgtacttg gaattgatgc actggttata
    29221 tttttattcc cattggcagg atttaagatg aatggaaagt taagtatgga acaaactaag
    29281 aatcaaagta ggtctattgc aatatcaatt ttggcattta tagtaataat aactgtatta
    29341 tattttaaac aagttggtaa gtagagcata attgtataag acatcattag agtatgaggt
    29401 gagtttatgg aagaaagaaa attagcacca aacaatgaga gggaagctct cataaaaaga
    29461 ttaaaaagaa tagaaggtca agttaagggt atacaaaaga tggtggaaca agaacgttat
    29521 tgtgttgata tattggttca aatatctgct ataaggtctg ctataaatag agtaggcaca
    29581 attatcttag agaatcatat aaaaggatgt gtagcagaaa gcattaaaca tgatgatgct
    29641 gataaaactg aagagatgat aaaagagctt atggatacta taaataaatt tacaaaataa
    29701 ggaggcggtt agttatgaat caacaaggat ttattatgga aattgttgat gatagaactg
    29761 caaagttaaa aatgcaaaga cattcagctt gtgctgcttg tggaaaatgt gctactacaa
    29821 attcagcaga gtcaaaagaa atattagtag aagtagacaa cacaattggt gcaaaagttg
    29881 gtgaccatgt agaagtgagt atggataata tgaatgtatt aaaagcagct gtaatggctt
    29941 atataatacc tcttatagca cttcttgtag gaacaatagg gacttattat atattggggg
    30001 caattggaat gacaactgga gttgaagcca taagtggatt agttggaatt tgtcttacaa
    30061 taatctgtta tttatactta aagaagaatg acaaaaaatt tagagacagt agagaattta
    30121 taccagtaat aacaagaata ttaattgacc tttaagataa ttataattaa aaaatagcaa
    30181 tgtgcttttt aaataaatac tcaatacgta tttgtagagt ttaagtacat tgctattttt
    30241 atatttttat tttgattttc tgtaaggaat aaagtttttt ctgattttca aaagattcaa
    30301 tgttcttaca aaagaagtta caactaatac accaagtgct attgcagcac ttagaaatag
    30361 cgcatctgta ccttttgaca tagccaaaga ataatttttc tgaatcaaag acaacattgt
    30421 attatatagc ccaattcctg gtattagagg aagaatacct ggaattacga acacaatagc
    30481 tggttgcttt agttttcttg ctaaagtctc actgcacgct gagaccaaag cagcagcgat
    30541 aaaacctgca aaaactgcat ttgtagtaaa attaaataaa taaacatata caatccaacc
    30601 aattccgcca gttactccag ctggaagaag tagatatagt ggagcattaa agaaaacagc
    30661 aaatccagca gttgcaacac ctgaaaataa aaaatgcaaa atcatagaca tatcagtcat
    30721 tagaaaggac ctcctattct ataccatgta tcaaggacaa aaccaactcc agaagcaatt
    30781 gcaataataa tcatagcagc atcaaaagca cgagaaattc ctgatattaa attccctgat
    30841 attaaatctc taatagcttt tataaaagca actcctggga gtagtggcat tatagcgccg
    30901 actataagca ttttagggtc atctaaaatg cctatttcaa ctagtagaac tcctgaaagt
    30961 gcaattaaaa aagaagatac taaacaggaa aatgcagata ttgcacttat cttcatcgtt
    31021 ttatcataag taattgcagc aaagattgct attataaacg taagtataaa atttaataca
    31081 taattccctc caagcaaaca agcaaaacaa gcagatgcaa ttcctgtaca agagtaaaat
    31141 aaccataaag gataaggttt tacatcttgg atttcataaa gacgtgcaat ggcattatca
    31201 atatcatact ctttgtcact aacaaattct cgagaaaaac tgtttaataa agaaatctta
    31261 tttaagttta tacctcttga ttgaatcgtt ttcataaacg aaaagccatc aaatttctca
    31321 tctgaaataa ttattactgt aggagttgta aaaatattta catgataaaa ccctcttgac
    31381 ctgcatattc taaggacact gtcttcaacc ctagatgttt cagctccatt ttttatcatc
    31441 agttccccta caaatagagc tagttttaga atatttttct tatattcaag ttcctcattt
    31501 tgattcataa atacacctcc aaattaaaaa acgtaatatt gaaattatat caaattttta
    31561 agtaatattc cttaatatct atataaatat attatctttt ttttgtttca aaatagtcac
    31621 atttaaatta tatccaatta aaagaattag acaatattat ttattatatt ttaacttaaa
    31681 aataaagaaa gtaactatgt taaatatgga aaaatggcaa aacacttgac tattaattgg
    31741 taaaggacta taataataaa ttatcatatt gataaaaacg aaaattatga aatgtctgta
    31801 aaaataaaat ttaaataata actaggagga gtaatatgtt tgagaacttg aaaaaagcgg
    31861 accctgagat ttatgaaagt atgaaaagag agttaaaaag acaacaaaga aatattgaat
    31921 taatagcatc agaaaacata gtatcagttc cagtaatgga aactatggga agtcatctta
    31981 caaataagta tgcagaaggt tactcaggca aaagatatta tggtggatgt gaatacatag
    32041 atgaagttga aactcttgca atagatagaa tcaaaaaaat atttggagca gaacatgcta
    32101 atgttcaacc tcactctgga gcaaatgcaa atattggtgt atattttgct atgttaaaac
    32161 caggtgatgt tgttatggga atgaatttat ctcaaggtgg acatttaact catggtgctc
    32221 cagttaatat ttctggtcaa tattataaat tttatgaata tggtatagat aaagacagtg
    32281 gacttataga ttttgatgaa gttagaaaga tagcacatga agtaaaacct aaaatgatag
    32341 ttgcaggagc aagtgcatat cctagagaaa tagattttaa aaagtttaga gagatagctg
    32401 atgaggttgg agcattgctt atggtagata tggctcatat agcaggtctt gtggctgctg
    32461 gtcttcacca aaatccatgt gaagtggctg attttgttac aacaacaact cacaaaactt
    32521 taagaggacc tcgtgggggt gttattcttt gtaaagaaaa atatgctaaa gacatagaca
    32581 aagcaatatt ccctggtatt caaggtggac ctcttgaaca tataattgct tctaaggcag
    32641 tttgctttaa agaagcttta agtgatgagt ttaaagaata tcaggtacaa gttgctaaaa
    32701 atgcaaaagc cttagctgaa gaacttatta aaagagattt taaattgatt tctggaggta
    32761 cagataatca tttaatacta ttagatttga ctaataaaaa tataactggt aaagcagcag
    32821 aaaagagatt ggatgatgct tatataacag ctaataaaaa tacaattcca tttgacccaa
    32881 atggtgctct tgttacaagt ggaataagac ttggtactcc agctgtaact actagaggta
    32941 tgaaagaaga agatatggca ataatcgctg aggctataga cctatgttta acttatgatg
    33001 aagaatctaa ggctagaaca ttggttgttg gtttaactga aaaatatcct ttatatgaag
    33061 aatataatat tatggattaa ttataaagaa caactaaata aaatacattt aaataattac
    33121 aatgattgtg tatgtatttg aatatattta gatataaaaa aggtgtctca aaatgaactt
    33181 tttagtttat gaggcacttt tttgtatgga atcgaacata tttgtattat ttaaataata
    33241 aaaaatatgg ttatctctat ttttagatgg tctctttgta ttttttaatt aaaactttaa
    33301 gatttcttaa gaattatact aggtttttct aaagatttaa agtctatact tataagtata
    33361 gtaatcatat gaaaagaaaa gctttaacga ggagggaatc ttatgaaggt attaattctt
    33421 acaggaaaat ttggtatggg tcattactca gcatcaaatt ctttaagtga agatataaaa
    33481 gcaaaatttg ataattcaga aataataatt aaagatatat ttgagtacat tatgcctaac
    33541 tattcagata aaatgtacaa gactttttct attcttgtaa atcggggaag tagtctttat
    33601 aatttatttt ataaatgtgc tgaaaatgga aagaaagata taaaatttac tttttcagat
    33661 tattttttaa ataaattaga tacattactt catgaagtac aaccaacagt agttatttca
    33721 acttttccat tttgttctca attagtatca agatataagg aaaaatataa ctcaaatctt
    33781 cctttaataa catgtataac tgatataagt agtcactcag aatggattag taaaaataca
    33841 gactgttatt tagtagccag taaatctact aaggaagaac ttgtttttaa aggaatagat
    33901 gaatctaaga ttaaagttaa tggtattcca gtaaaaaaag aatttaaaag aatagaacat
    33961 gtaaatcatt caactaaaaa aaatattctt ataatgggtg gaggattagg attactgcct
    34021 aaatcagaac aattttacaa agaattaaat agtttaaaag gagtaaaaac tactgtaata
    34081 actggtaata ataaaaaaat gtactataaa ctatatggta gatatgaaaa tatagaggta
    34141 gtaggttaca ccaatgaagt atataaatat atgaaagatt ctgaccttat tatttctaaa
    34201 ccaggtggaa taacactatt tgaaacaatt tattcagaac ttccaatatt ggcatttaat
    34261 ccatttttac aacaagagat agataatgct agttttatat taaataatga aattgggaga
    34321 atacttggta aaaataaaaa atactatgta gatgagataa aagatttaat ttatgatgat
    34381 gctactctta aagaaatgag cagtaacatg aaagaattaa aaaaacaatt tgataataat
    34441 accttagaga atattttatt ttcacttgat gaacaaggag cgtgtagaga atgtatgtag
    34501 taggtttaat tatcgttgtt gcattgattt ttttagtcca ttcaattata cctacatact
    34561 ataataaact attaaataaa gaggtattaa aaaatatggc tggagaaaat gaaattgcac
    34621 ttacatttga tgatggtcca gataagagat atacagaaaa attactagat gtgttaaaag
    34681 aaaatgatat acaagctatg ttttttgtag tagcaaagaa tgctgaaaaa gagcctgaaa
    34741 ttataaacag aatgttgaga gaaaatcata tagttggttt acattcattg gaacacagaa
    34801 atgcatggct ttatagttat agttatgtta aaaaagattt tattgaaagt acaaatataa
    34861 tgaaaaattt aggtgtagat gtaaactact atcgtccacc atggggtcat actaatatat
    34921 tttcaaattc atttgttaaa aaatataatc taaaaatgac tttgtgggat gtaatggcag
    34981 aagattggga gaaagatagt acagtagaca ttattataaa caagttaatg agtagaacaa
    35041 aagaaaattc tataatttgt ttacatgatg caggtgaaaa ttcaggtggt gcagtaggtg
    35101 cacctgagcg tactattgaa gctttaaaga tagctattcc aaaacttaaa gccagtggtt
    35161 taaagttcgt aacaccagaa aggatgtagt tatgataagt aaaactgaaa agaaaaataa
    35221 atgcctaggt agtgtagctt ttttagtttt actaatgggc ataacaggat attttgtttt
    35281 tagagggcag tcagttgaat cattgataaa atcattaaaa ggtgcaagcc ctatgtttat
    35341 actaattgga tttgcaatga tgtttatata tgttgcctgt gaaggtataa atatatactt
    35401 aggtatgaaa gctttaaacc aaaagactac tcttttaaaa tgtatgggat atgcttttat
    35461 tggattttat tttagttcta ttacaccttc agcatcaggt ggtcaaccag cacaagttta
    35521 ttatatgaaa aaagacgata taaatatatc atattcttca cttatactat tagtcattgt
    35581 tgttattcac caagtagtta tactggcata tagtggaata atgttcatta tggaacgtga
    35641 gtttatatta aataatgtaa gtggtatgaa cattttacta atatatggtg taataacaaa
    35701 tgttgctctt gtcattggag taattgcaat tatattttca aaaaaacttg taaacaattt
    35761 tataatatca ataacaaatt tattaggtaa gttaagaata ataaaagatg ttgaaagttc
    35821 aagaaaagtt ataatatctc aaattgaaga gtatgttaaa ggtgctcaat atataaagca
    35881 gaatccaaaa cttgtagtcc aaattttagt cataactatt gtacaaataa cagctatgtt
    35941 tttagttcct ttctttgtat acaaagcttt tcatctatca acatatactg tatttgagat
    36001 attagcgata caatccttgc ttaatattgc tgtttcttca ttaccattgc caggggctgt
    36061 tggagcttct gaaaatagtt ttatgacatt atttaagata tttttccctg gtcacttatt
    36121 agttccggca atgttactta gtaggggaat aagtttttat gcatttgtag ctataagtgg
    36181 attgatatgt atagtagtac atgtaaaatc ttctgaaaaa gtaaaagcag tgaaaaaagt
    36241 tgcttatgta agataatatt atatagatta tttttattaa tatgtcaatt tgtgtgtata
    36301 ttttaattaa gctttaaaca tgtttacagg agtagaaact attaaaacgt gtgacattgc
    36361 taagcttttg ctaataaagt ataatatttt atatagtttg aaatatttaa gaaatatagc
    36421 aaaaaaagga gcttggtgat gaataaagag attccaaaaa aaattttagt agctgatgat
    36481 aatcctgaga ttagggaaat cgtagaaata cttttaactg gtgaaggtta tgaagttatt
    36541 atggcaacga atggagaaga agctgtaaac ttagtagata gtacgattga tttgattatt
    36601 ttggatgttg taatgcctgt aaaaacagga tttgttgcat gtaatgaaat tagagaaaaa
    36661 acgacagcac caatattatt tttaactgca aaaactcaag actctgataa agttattgga
    36721 ttttcagcag gaggagatga ctatttatca aagccttttt catattctga actaatttca
    36781 agggttaagt cgctacttag acgttattat atataccagg gaaaggaaaa ggaaagagag
    36841 ccaaatatat taaaaacaaa agagttatgt gtcaatttag atactcaaga tgttacacta
    36901 aatggagaac ctgtgttttt gacaactata gaatatagta tattaattct tatgttgaaa
    36961 aatagaaaaa aagttttttc gtctgaaaat ttatatgaaa ctatttggga tgagcagtat
    37021 ttttatacag caaataatac aataatggtt catattagaa atttaagaaa aaagttagaa
    37081 aaagaccaaa aaaatccaca atatataaaa accgcatggg gaaaggggta ttatattgat
    37141 taacaaaatt aagccatcta agttgggagt tatactattg atatatgtag taatctcagc
    37201 tgcagtggct ttcattttaa atataccatt ttactctgct gttgaatcta tagtaaaaga
    37261 tgtatcagaa gggaaagtat attttaaaag agaagtaaat caacttatgg ataattttca
    37321 aacttatgtg aataacaatg gtataagagc agatgatgga gatgatatag caaaatggaa
    37381 tagtgataat tggtttgttt ctatgaagat atataaagga aataaggttt tttatgatac
    37441 attatactat cctaatgaag tacctgataa gagtgaggaa aatgagtttt atagcagtcc
    37501 catggctaga aactatgaga tacaattttc tgatattaaa gctaatatag ttgtagtagc
    37561 tttatttaga tttagatttc aaaattttat agaagcaatt tctattacat ttatggcact
    37621 tacatttatt ataacatttt tactgttgtt tagtagaaag ataaagtacc taaggaaaat
    37681 agaaatgggt ataaagatag tagagagtgg cagtttaaag tatagaatcc cagtaaaagg
    37741 taatgatgaa ttatcatcac ttgcatctag tattaatgag atgagtcata cattggagaa
    37801 tcaacttata aaagaaaggg agatgaagaa taaaaataaa gatatagtaa cttcaatatc
    37861 acatgatgtt agaactccat taacgtcagt aatttgttat ttagatttga ttaaagacca
    37921 taaatacaat agtcctgagc aattggaaca atacataaaa aatgtaaggt ctaaagcata
    37981 tcaaataaaa gatttaacag atgacctttt tacgcatttt gttaattctg gagaggaagt
    38041 ttcaaaaggg tatgaaaaaa taaatgctaa tgaatttatt tttcaattac ttttagatag
    38101 ttcatataca ttggaggaga aaggatttca tataacaata gaaaatgaac tttataacca
    38161 atatcatatt tatgtagatg ttacacaatt tagaaggata tttgataatt tatgttctaa
    38221 tataataaaa tatgctagga aagataagcc tatagtattt ttaattaaag tagaggattc
    38281 taaattacta attatacaaa aaaatagagt aagtaatttt tctaagaatg tagaaagttt
    38341 tggaattggt ataaagaatt gtgagaaaat agttgcatat cataatggaa gcataaatgt
    38401 aaattcagat gataaagaat ttgctattga aatatctatt ccagcaaaag aatcataaaa
    38461 atttaaatta tatattgtgt aattgctatt atatatagtg taattgctta tgtaaaattc
    38521 tatgaagcag gaagcatgtg actttagtta tgggatgttc aatattgtgt acctctaggc
    38581 aagtaacaag tttacttaca agaccatata atattattat cttaaaaaaa ggggacataa
    38641 taatatggtt ttgacaggag cacattatat ttacattcta tttatggtaa ttatattaat
    38701 tactatgatt atgaaaaagg atacaatagt accatgtata ttaggtgttt tttttatggg
    38761 attgttcttt gaaaaaaaca tctttggtgc tataacagca gtgtttaact cttttattat
    38821 atctttaaat gagttgggtc caattatctt gattatagct attatggttg cattatctaa
    38881 agccctagaa gccaataatg ctatacagta tatggtgaga ccattttcga gagttataaa
    38941 aaattctaat acagcatttt ttgtaactgg atttgttatg ttagttcttt cttggttttt
    39001 ctggccaact ccagctgttg ccttagttgg agctgtattt ttacctgttg ctatgagagc
    39061 tgggctacca gcaattggtg ttgcagtagc attaaattta tttggtcatg gtcttgcctt
    39121 atctacagac tttgttattc aaggagctcc aagtataaca gctggtgcag caggtgttgc
    39181 agtatcatat gttataaatg atggtatgat tttgttttgg gtgatgggaa tcgtaaccat
    39241 atctatggca ttttatacat taaaaagaga tattaacaaa ggaatgttta gagaagaact
    39301 aaaaggtttt gaaagtgaag aagtagaaga gtttaatgga aaatctaaaa tagcaactat
    39361 tttagtagct ttgggatttc ttgctgatat aattgctatg tatgtatttg acctaaaagg
    39421 aggagatgca tcagctcttt tgggtggaac agcagtattt ttaataataa ttataaatgt
    39481 tataaatttt ggcaaagata gccttgaaaa tgtatgtgag aatataattg atggttttgt
    39541 gtttgggata aaaatatttg gagcaattat accaatagca gcatttttct atatgggtga
    39601 agttgcaccc ttgacaggtg tatttggaaa agtattagca ccaggttcac aaggtttatt
    39661 atcagatata ggcatagctc tttctcaaac aataccactt aataaatttg ccgtatcagg
    39721 tatagaaact gtagtgggag caataactgg gcttgatggt tctggatttt ctgggatttc
    39781 attagtgggt tcacttgcct ctgtatttgg aactgctata aatgcaagtg ttggtgcatt
    39841 agctgcatta ggacaaatca gtggtatatg ggtaggtgga ggctgtctag ttccttgggg
    39901 tcttatttca gcagcggcaa tttgtggagt tagtccaata gaattggcaa agcgaaactt
    39961 tgtcccagtt ataaccggat tggttgtaac aaccatagta gcaatgttta ttatttaata
    40021 aatcgaataa atctttaatt gtataaatta aaaatagatg tgtagctata atttattata
    40081 attgttttac taattctaag ccatacatct atttttattg atatttttat tagtattctt
    40141 taataaaata atatttttca ttatactata cataacatct aaaatactgt tatctatatt
    40201 taatatcttg ccaaattttt tgatgtttta ttgccctgtc ccaccaacat atataagcta
    40261 tcataagttt tttacctata ctatcaccaa acaaaaattc taattttaat ttattatttt
    40321 ataacctata ttatattaac tatattagtt tgtagacttt agatgtaatt ctaaatatta
    40381 atactccaag agttcaaatt catatcctag ttttcttgca tttgatataa aatcatttaa
    40441 aatttctgta ctagttttgg aaactgcatg tagtaacaag atagaaccat catgtagatt
    40501 atccattatt ttttgcgttg cttcttcatg tgatggttgt ttatcagtat cccagtctct
    40561 gtatgcaaaa ctccaaaata cagtcttgta tcctaaattt ttagtcattg ccaagctttt
    40621 ttctgagtat tttcccatag gaggtctaaa aaatttaacc atatctttcc cagttacatc
    40681 tttatataac ttttcaacat catataattc gtcattaaag ttttttagat tgcttgtttt
    40741 tgttggcata gatggatggg ttttactatg atttccaact atatgtccct cagaaaccat
    40801 tctttttact aaatctttat tttcttttat atatggagct gtaacaaaaa aaactgcttt
    40861 aacctggttt tgttttagag tgtcgagtat ctttgtagtg tatccatttt cataaccttc
    40921 atcaaatgta agatatagtg ttttttgacc atcttttgta ggtccattgt atagggcatc
    40981 atagtcagaa aatttaaatt caatgtccgt atttacttct ggtgttttat gcttattgtt
    41041 tggtatataa aaccaatcaa gagtagtgtt atctaaagaa gatacatcta atttattatt
    41101 atcattatta gtagtggctt ttgatggttt atctgttccg tctgaaacta ttacattgga
    41161 agtatcttta ccactatcta ttttttcctt atcttcttgt aactgtgttt ccttattttg
    41221 attttcgttt tgattgtttt gtgaatttga acatccaaca ataaaaaaaa tagaaataga
    41281 aagtagtgtt aaataatgca atacttttct aaacattttg aagctccttt ctaaattaat
    41341 aataattgca tataataata attatatgat taattacaat tgcatatagt attattataa
    41401 ttggaaatta ctattaataa tagttatatc tttaaaaata aagtcacaat agtatgacaa
    41461 agggtgaata atcaataaat ttaaaaaaaa atgaaaaaaa tagttgacca tattatgaga
    41521 agatgttatt ataataaatg tgctcaacaa gaagtaacaa aataacaagc acaaagaagt
    41581 taattgaatg aaa
//
LOCUS       DAEORM030000032        41575 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.032, whole genome shotgun sequence.
ACCESSION   DAEORM030000032 DAEORM030000000
VERSION     DAEORM030000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 41575)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41575)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 41575)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41575
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.032"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            297..1568
                     /gene="serS"
                     /locus_tag="KRH23_002226"
     CDS             297..1568
                     /gene="serS"
                     /locus_tag="KRH23_002226"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006441208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004828 - serine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006434 - seryl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HHS5225504.1"
                     /translation="MLDIKRIRENLDCIKKAMERRGEKDFNLDEVVKLDDERRKILQE
                     VEVMKNELNTASKNIPNLIKEGKDVENEKIKLKELSDKIKVIDQNLKEVEDKMEYLLM
                     RIPNVPHPEVPQGETDEDNVEVRTWGKTTTFDFESKAHWEIGTKLGILDFETASKITG
                     SRFTLYKGLGARLERALLNFYLDTNTKVNGYTEVIPPFMANRNSFLGTGQLPKFEEDM
                     FKIEGLDYFMIPTSEVPLTNIHANEILKFEQLPINYTAYTPCFRSEAGSAGRDTRGLV
                     RQHQFNKVEMVKIVAPEESYNELEKLTNNAENMLQLLNLPYRVVKICTGDLGFTASFK
                     YDVEVWMPSYNRYVEISSCSNCEDFQARRAGIRFKRDKDSKAEYVHTLNGSGLAIGRS
                     VAAILENYQQEDGSVVVPEVLRPYMGVSVIK"
     gene            1893..3398
                     /locus_tag="KRH23_002227"
     CDS             1893..3398
                     /locus_tag="KRH23_002227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HHS5225505.1"
                     /translation="MKIQNTEWGYIEWKHTYDENNPKQAMNIYIAVTMPGKKHFNHVH
                     YGQEQMIYILEGEGLYIINGVWKPFYQGMIFYIESGSTHETINTGDREIKELIVSNNV
                     DDVGESEVIDINPNNYLKKTLINYSESTLNLYAAVESIRGQFIDPFKIPLIIYDDSWN
                     IVLKNPYFPLFCFEKCNPMKFPQNCDCMNQKSSNQFVCEYGITIYNIPILYKSNSIGV
                     IRGGYVLLSDLNLDTEHNNLYDIPEGAARSIKRLLKQISKNIINFCSFNDIRKDLQEK
                     EKTIARTYHYGEQLEMNLKVAQDMVTNLRINHHFLFNTLNSMASIALDDGSYDLYSAI
                     IDLSRMFRYTMRSDLRFVELESEILYIKNYLNLQKLRYGDALKVKYLILEKLYNLSVP
                     FNFIQPIVENAFTHGFRDIDTEKRIEIIARLDSQYAIIEIHNNGTILDGNNIDKIKAG
                     IRSNNGHGLSLIYTKFTSAYGNNFDMDIKSSDNEGTYIMIKIPIENYKEYV"
     gene            3512..4210
                     /locus_tag="KRH23_002228"
     CDS             3512..4210
                     /locus_tag="KRH23_002228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HHS5225506.1"
                     /translation="MRRALIIDDEEAVLKIITHFIEMKDMPIKIVGKATSGDEAVDKI
                     IGLEPDIVFIDIQMPIYNGLEVIEKTSHLSKKINFVVITAFNYFEYAQKALRLNVKDI
                     LLKPLDMKEFTKSVEKIIGYQYTNNDLLNEILEYINLNYSNDLKLNDCARLFLTNPSN
                     ISRIFKSNLNTTFISYLNHIRIEKSIELLENTTKSINEIAEIVGYNSLNNFYKNFKIE
                     KGMTPKVYKLNTKN"
     gene            4495..5583
                     /locus_tag="KRH23_002229"
     CDS             4495..5583
                     /locus_tag="KRH23_002229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YkvI family membrane protein"
                     /protein_id="HHS5225507.1"
                     /translation="MSDKVNMKNIICIAGAYLATAIGSGFATGQEILQFFASQGYMGL
                     IGALISMVLFSFLGAEVITRGRELKLKEPTRIYTFYCGKILGKFYEWFSPIFLFGILI
                     VMISGAGSTLTEYYGINPYLGRVLMAVATLITVSMGLEKLVSILGRIGPVIAVFTIAV
                     GLISLFKHFDGLSMVGEAMKNIEVTKASESPIVSGVIYNTLNIIVMIVFLTGMGASIE
                     SKKDAFWGGLLGGIVFMTAGIVMYLAMISDIGNLYMKEIPSLYLADNISPIVGVCFSV
                     ALILGIYTTAVPLLWSVTNRIVEDEHPKFKLVTTVIAILACIGGFLPFGKLVNILYPY
                     TGYTGLLILVCMVYKAITCRKKSTQSQE"
     gene            5822..7012
                     /locus_tag="KRH23_002230"
     CDS             5822..7012
                     /locus_tag="KRH23_002230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HHS5225508.1"
                     /translation="MHELILISEKYKEDILDFFTDIHMHPELSFKEFRTTKAIKDLLV
                     SLDIEILDLGMETGVVGLLKGKYDGPTVALRGDIDALPIYEEVDIKYKSRYDGIMHAC
                     GHDIHTSCLVGCAYVLSHIRDSLHGNVKFIFQPAEEVNKGAKMLVERGVMENPKVDAI
                     FGLHNHPDIPCGKIGVKLGGLMAAVDTIKIEVNGFGGHGGIPNRTIDPIVASSAIIMG
                     IQTIVSRNISPLESAVISIGTINGGTANNVISEKVDMTGTCRSFSNEVRKKISENLEN
                     IVCEIARGYQATAKLDYLFDLPAVINSKEMYAIACKSVCDLYSEDAIVDPIPSTGGED
                     FSIFMEKAPGFFYWLGVGNKEQDCIYQWHNPKFKADKNSILVGTNVLCQSVINYMDKL
                     KNKI"
     gene            7103..8605
                     /locus_tag="KRH23_002231"
     CDS             7103..8605
                     /locus_tag="KRH23_002231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbgT family transporter"
                     /protein_id="HHS5225509.1"
                     /translation="MRALNVVERAGNKLPDPVTIFLLLCIIVVILSAVISNLGVEEIH
                     PSTKEVVKVVNLLEKEQIQSYLGSIVTNFQSFAPLGLVLVTMLGAGVAEKSGFMEVLM
                     KKGISKVPQKLVTVAIVFAGMLSHTAADVGFIILPPLAALVFLGIGRHPLVGMFAAFA
                     GVAGGFAANVMLSTTDVLLAGFTIPAAQMMDPSYQGNPAMNLYFAFISAIVLTFAGAF
                     VTEKFIAPRFTKYNDSTNDKDIQELSELENKGIKYALLSLLVVVVVIVALCIGDNAFM
                     KDPETGSILSSNAPLMKGIVPIITIIFLTPGLVYGKVSKKIKSDKDLVSMMGSSMSDM
                     GGYIVLAFIASQFINLFNLSNLGTILSITGAKLLAESGIPSYGLIIGFILLSGFINLF
                     VGSASAKWAILAPIFVPMFMLLDFNPALTQIAYRIGDASTNPISPLFPYFPVILAFAR
                     RYDKDIGIGTVISNMIPYSVVFTLIEIIILLLFMGIGIPLGPGGGISYVL"
     gene            8677..9933
                     /gene="glyA"
                     /locus_tag="KRH23_002232"
     CDS             8677..9933
                     /gene="glyA"
                     /locus_tag="KRH23_002232"
                     /EC_number="2.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004372 - glycine hydroxymethyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0070905 - serine binding [Evidence IEA];
                     GO_process: GO:0019264 - glycine biosynthetic process from
                     serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HHS5225510.1"
                     /translation="MLKTTKISDPELYKIVADELVRQEHNIEMIASESTAPTEVLELS
                     GCVFTNKTEEGYPGARFQAGSEEADKLETLAIKRAKEVFEAEHVNVQPYSGSTANYCV
                     YSSILKPNDTVLSMRLDQGGHLTHGSAVNFLHDIYKYEFYGVDPNTGRIDYDALEAKA
                     KECRPKLIIAGASSYPRLIDYERISKVAKEVGAYFMVDMAHVAGLVAAKVIPSPVPYA
                     DFVSSSTTKTFCGPRSGIVLCKAEHAKKLDKGVFPGTLGSIHLNTVAAKAFSLLYLST
                     DKFKKIMEQVVVNAQTLASELISHGFSIVSGGTDNHIVMVDLRSKNLTGKQFEKALEY
                     VGITVNKNVIPDDPQSPFVTSGVRIGLTSISQRGLKEKEVIQIAEIMNKVAENIDNKE
                     VLDECKAEAQELISKFPLYPEGYFED"
     gene            10105..12879
                     /locus_tag="KRH23_002233"
     CDS             10105..12879
                     /locus_tag="KRH23_002233"
                     /EC_number="7.2.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005388 - P-type calcium transporter
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006816 - calcium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="calcium-translocating P-type ATPase, PMCA-type"
                     /protein_id="HHS5225511.1"
                     /translation="MRYYNKPTKEVLKYLKTNPEIGLDDNEVEERKLRYGLNEFTIKE
                     GRTFWDELGESLTEPMILILIGAAVISSFVGELHDALGILGAIFIGISIGIITEGKSK
                     KAAHALSKLTENIEVKVLRNGKIIKISKNDLVPGDIVYIETGDMIPADGRLIQSINLK
                     LREDMLTGESDDVAKNADAVLDMEVVYSKTEIIEQDAIPAKQVNMVFGGTLVAYGRGV
                     MVVTHTGDKTEMGKIAQNLSNEDQQTPLQIKLGKLGAKIAGISGIIATLLCMFMIIQM
                     QRKGMLILDTSSILSFLQSLEPAKNAYMVCIALIVATVPEGLPTMINITLAITMQKMA
                     KINALVTKKEACETIGSVSVICSDKTGTLTQNKMMVEVAYVDGKYISGGEYQSNSYFE
                     QNCIVNSTADIEKEYNSFKYIGSATECALLLYHNDKNYNEMRKQTYLISQIPFSSEEK
                     KMSTLIRQGDSDILLSKGAPEVLLKKCSYVQQGKNIVPITPKVEKSILDEIKKLQIKS
                     MRTLGFAYKKMSNSKTEVAMTSEGELNLIGNSRSYMKEDNLVFSGFVGIVDPLREGVK
                     DSIDKAFNAGVDVKMLTGDNINTATAIGNELGLLNDGKKAVEATYIDVLTDKELREEI
                     KGISIVARSKPDTKMRIVSALQKSGEVVAVTGDGINDAPALSQADVGIAMGISGTEVS
                     KNAADIILTDDSFSTIVEGIKWGRGIYENFQRFIQFQLTVNIVAFIIAIISQLTGKDM
                     PFTTIQLLWVNIIMDGPPALALGLEPVRDYVLKRKPINRHSGIIARSMFVNIIINAIL
                     IITIVFTQSAFNILGATSEEQGTVIFSLFAFSALFNALNCREFGLNSTIPNFFKNKLA
                     LQIIVVTGIIQIIFTQVFQSFFNSVSLDFDMWIKIILFASTILLSNEFVKLILRTMKN
                     SRTMNFNSKN"
     gene            complement(12944..13129)
                     /locus_tag="KRH23_002234"
     CDS             complement(12944..13129)
                     /locus_tag="KRH23_002234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HHS5225512.1"
                     /translation="MFFISDIYTKSPIKFDTPLQKEAYKILQKLDIDFECVDTDEAIT
                     MEDCVQINKKLNMKMVI"
     gene            13504..14682
                     /locus_tag="KRH23_002235"
     CDS             13504..14682
                     /locus_tag="KRH23_002235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HHS5225513.1"
                     /translation="MFSKILVKTFIRDSENVQNTDVRNKYGYVAGVVGILSNLLLFVI
                     KVFIGMLTSSIAIMADAFNNLSDMASSAITMIGFKLASKPADKEHPFGHGRIEYLSAL
                     IVAFMVMLVGLQFVKSSIERIVNPIPVKFEVIPLILLIASIMIKIWLSRFNKFMGNKI
                     DSSALKAVSLDALGDVFTSSCVVISFIVARFTNFPIDGYVGIVVSLVILYAGFSLVKD
                     TINPLLGEAPDEEMVNSIIELLLSYKYIIGTHDLIIHNYGVGRCIASIHAEIPSNIDI
                     MEIHEIIDTAEREISEKLDIYLVIHMDPICLEDKEVMSAKKELEEILKKNSLVKSMHD
                     FRIVGKGSKKNLIFDIVVNPSEFSKNMSEDDLKEDITKLVKEINPEYNCVIVVDKDFI
                     "
     regulatory      14809..14894
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF01786"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cyclic di-GMP riboswitch class II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01786"
     gene            15012..17930
                     /locus_tag="KRH23_002236"
     CDS             15012..17930
                     /locus_tag="KRH23_002236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021362860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SrtB-anchored collagen-binding adhesin"
                     /protein_id="HHS5225514.1"
                     /translation="MKKGNRKALLISLIMILSMVVSTIYPTVSYASELGENSQIQSGS
                     TNSSTGEEKESDNKKPEQTPEKDKATDNKKPEQTPEEEKPTDNKKPEQTPEEDKSTDN
                     KKPEQTPEGEKPIDNKKPEQIQEEDKSTDNKKSEQALEDEKPLDNKNTEKTPEEDNLL
                     EDENLLKVLEEELNEENEDYGFVVKINNNTIETESMKKISFNLTYTPTSKGIQAGDSI
                     TFKVPDVFNKVNLDYTSECFDKTESNGEYTLTFRELPNGQSVMQGKIGLEAYVKKVDE
                     DTNAKIHIETTGKIESGSGDIDVEIKPGDKTDVPDAKGILKKLVEGKKSTTVFMPVKN
                     KDINYSIQVNEKQEELKDIILYDELPEGLTLINGSVSVVTSDGKEVSDFNIEQSKNSI
                     SVNFGNIDKSYTVKYKARISDKNAKHGNKYKNVARIESDGKKIQEDDATVSIFDRGDD
                     YLLTKGHSGATNITQVGQVINYQISINDDKSPISNVVITDNIPEGMRLTTSGEAGHDF
                     RVVEIPMNGSWTPWSKEKIANNISYEVEEKRNESGQVDKVITGFTINLSKEEVESKFF
                     IAYTLKVISIEDSYINRAVLDANNSEIDKNDEINFKKNSGLISAKKEVDKKVLNSSDN
                     QIVKYKINMSTYGVYDAGQVNLLDEVNSALEISNIKYSDNLELKKEAGDGKNTIRLVN
                     KYEFKQIKEGEPVQSWVTFDADFTNVKVGETIQNVAQINGSSPPGVETTKQGYAFEAK
                     KVDALDKNVLSGAKFNLEDAFGNIVVKDLVSDEDGIIQSSIKKPGTYYLVEIMAPSGY
                     EKLKDKIKVEIGNKDIGRIVDIGNIENIRQENPPVNPPAPPNTDEPIVNPPVPPSTDK
                     PRKPSSSSDTEDTIVINPPVPPSEDIINPPIPEVLNPPVPPSEEMIETPVKQIIPIPE
                     VVKPSVSEEKNNKVKDDTLVNPPVPPKTGDSTTIIGEILLVIGAIVGLIVLRRNKNTI
                     "
     regulatory      18115..18200
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            18300..18962
                     /gene="zmp1"
                     /locus_tag="KRH23_002237"
     CDS             18300..18962
                     /gene="zmp1"
                     /locus_tag="KRH23_002237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease Zmp1"
                     /protein_id="HHS5225515.1"
                     /translation="MRPSKKLLIAIISIFLISSVPVSAHADSTTIQQNKDTLSQIVVF
                     PTGNYDKNEANAMVNRLANIDGKYLNALKQNNLKIKLLSGKLTDEKEYAYLKGVVPKG
                     WEGTGKTWDDVPGLGGSTVALRIGFSNKGKGHDAINLELHETAHAIDHIVLNDISKSA
                     QFKQIFAKEGRSLGNVNYLGVYPEEFFAESFAYYYLNQDTNSKLKSACPQTYSFLQNL
                     AK"
     gene            complement(19081..20043)
                     /locus_tag="KRH23_002238"
     CDS             complement(19081..20043)
                     /locus_tag="KRH23_002238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HHS5225516.1"
                     /translation="MKKGYVYIILTTLFFSSMEISLKTVTNDFNPLQITLSRFFVGGL
                     VLLPFAVKRLRALSLSITKSDLKYFAFLGFMCVVVSMSLYQLAVLNTKASVVAVLFSC
                     NPVFVMLLAYLILKEKIYRHNVISLILEVLGIIVIINPLHTKLTLSGIFLTLSSAIIF
                     SMYTVFGKRKTLKFGGIVVTCFSFIFGSLEMLILVLLTKINFIADILNKNKLHVFANI
                     PIFSGYTLHNMPIMIYVFVFVTGVGYALYFMAMEATSTSLTSLVFFFKPVISPILALL
                     ILKEIIPINMVIGILLIVIGSIISIIPTIITQMHNKHVEALYKE"
     gene            complement(20213..21403)
                     /locus_tag="KRH23_002239"
     CDS             complement(20213..21403)
                     /locus_tag="KRH23_002239"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HHS5225517.1"
                     /translation="MISNKMQTLVANSSVIRAMFEEGKKLSDIYGEENVFDFSIGNPS
                     VEPPETIKAVINDILNEESPNLVHGYMNNSGYEDVRDAIAEHINKKDGLNLTRENLIM
                     TCGAAGGLNIILKTLLNPGDEVIAFAPYFGEYKNYTENYDGKLIEVPTNIETFEPDLD
                     ALKNAITPKTRALIINTPNNPTGVIYSEELLKNLGELLDSKQKEFNTSIYLISDEPYR
                     EIIYDGAKVPCVLKYYRNSFIGYSYSKSLSLPGERIGYIVANGQMDDFDDVMSSLNVA
                     NRILGFVNAPSLFQRVIARSLDAEVDVNIYKKNFDLLYNSLIDMGYSCVKPNGTFYLF
                     PKAPIEDDKKFCNDAKQFNLLLVPGSSFGCPGHFRVSYCVSYDKVKSSLPAFEKLAKL
                     YNLK"
     gene            21709..22155
                     /gene="bilQ"
                     /locus_tag="KRH23_002240"
     CDS             21709..22155
                     /gene="bilQ"
                     /locus_tag="KRH23_002240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bilirubin utilization transcriptional regulator
                     BilQ"
                     /protein_id="HHS5225518.1"
                     /translation="MDFKNLQYESLSYIICNLQKNFKLYCEKCLKPYKLTNGLYFYLI
                     YINKNRNCSLNDVSTEFEVDKAHTTRTISRLEQDGYIEKIQNPNDSRAFQLRVTDKGE
                     EVLGDIKNIFSKWDNHIKKEFSDKEYKELVKNLHVVKDIKTAVEEE"
     gene            22157..23251
                     /gene="bilR"
                     /locus_tag="KRH23_002241"
     CDS             22157..23251
                     /gene="bilR"
                     /locus_tag="KRH23_002241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bilirubin reductase"
                     /protein_id="HHS5225519.1"
                     /translation="MYCNLLKPIKIGNLELKNRVSFAPTSMGLKLEEKIKKFSDIAKS
                     GVALITLGDVSIRPSFHKVAISLSDEDGVMKYKKIVDEIHNSGAKVSAQLFCSDYDVN
                     LIKDTMNMGITSHDEIKKIMNDGVKDYITNMPKEEIKNIINLFKVTALNAKKAGFDMI
                     QIHGDRLVGSFSSSIFNNRNDEYGGTCDNRSRFASEIISSIRDEVKDIPIDYKFAIRQ
                     ENPHYGNAGVLLSEVEYFVKKFESLGVNSFHVTLANHSKLEDTIPTNNHPYFKEEGCF
                     LYLADEVKKHTNLPVCGVGKLSSPDFIESIISNNRVDMVSMSRQLLADSNWLQKVKDG
                     RVDEIKKCCYCNKKCADALQTRSQFGCILD"
     gene            23339..23869
                     /gene="bilS"
                     /locus_tag="KRH23_002242"
     CDS             23339..23869
                     /gene="bilS"
                     /locus_tag="KRH23_002242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein BilS"
                     /protein_id="HHS5225520.1"
                     /translation="MKSLVLYSSLTGNTKKIAYTIYDEIQEEKDIKDVNELVDYSIDY
                     ENYDIVFLGYWVDKGICDKNSKQVLENIHNKKIALFGTMGASKKGSYGASIIEKIESI
                     IPKDNEILGSFICQGKIAEGLKAKYKEMLKLSPDNEHILQQLNNHEESQSHPDEQEIY
                     EASMFAKNMMIKASIV"
     gene            24197..25030
                     /locus_tag="KRH23_002243"
     CDS             24197..25030
                     /locus_tag="KRH23_002243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HHS5225521.1"
                     /translation="MTIKEVEEKTGLTRSNIRFYENENLIKPLRNERNGYREYSDENV
                     ENIKKIAYLRTLGITIDDIRNIILQKVSLVEVVEKQEKVLETKISDLENAKTMCNKML
                     ESDELSYLNLKVEQYITELPEYWNKNKPVFKLDSVSFLYIWGGKITWGIITIACLLIA
                     ITVFPKLPPQIPIQWNNGVANYVDKKFIYAYPVICVVFRILLRPFIWRWLQIHAFYSD
                     TIADYLTNFMCFVALSIEIFSILFIYNIARHVTIIIFIDILVFIALLIIGVYKLFKKY
                     N"
     gene            complement(25280..26656)
                     /locus_tag="KRH23_002244"
     CDS             complement(25280..26656)
                     /locus_tag="KRH23_002244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5225522.1"
                     /translation="MKYKIGFLTTSYFMSDKFKQALKELNDTCEITFIELKGENPFNN
                     LPNIYYEQVDNFDGFVCSGIVPYSELIINIKDIKVPLNFLKLDERDFYKYLFKLLNSQ
                     KDIDFTKSFMDFLREDNNYYDIYSLIDSNKCPYTIKDFNIPQPVYDFKKLNDKLLEIH
                     LDLLRDNKINLSFTRNYIISCELNKLGYDCIYMVPSTESILNTFKSLVNEITLQNLDK
                     NKSATCIVTVNSSEYINEDLIFKNDEIQNQIYNTILNSLSRHGFYGVQVKKNDMKIEI
                     HTTKEMLNNMTNNYTDFFISEDLKEIKYSLNIGWGIGNTNIHAEQNARQANGKSASLN
                     GNCTFIVNDTNDTIGPLYSNKNSNNIEDSSIANKVASFIPLSNTNVSKIMCMINDRNS
                     NNVSAEILSDYMNITLRSANRILSILYKAGIATIVNTKLDNQRGRPKKIYKVDFLSFL
                     NKMQKLNS"
     gene            26924..28096
                     /locus_tag="KRH23_002245"
     CDS             26924..28096
                     /locus_tag="KRH23_002245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HHS5225523.1"
                     /translation="MNTYLNEISKFVDENREEIVSLWKEIVNMESYTHCKESVNKLAK
                     RLKFEFEKEGLDCELVDVGDNGSTLIGTLGSNINKKPIIFSGHMDTVFETGTFGENPF
                     KIIEGKAYGPGVLDMKGGIIISLYVIKALNKIGYKERPIKIVFSGDEEIGHKDSTGAD
                     VILREAKGGLCAFNMETGLVDNSLCVGRKGRIGCNIHVKGVETHAGNDFEGGRNAIEE
                     MANKILRIQKLTNLDVGTTVSVSVIKGGRVENSIPEDCSIKVDLRFEKVEEMENVKEQ
                     VREICKETYIEGTSTEVNFISEMMPFETTEDVMRFHTFVNEVSKENGFGELNAKRLGG
                     SSDASYLTIANVPTICSFGVRGEWNHTSREYAVVDSMFERVKLISTVILNLDKFEV"
     gene            28110..28757
                     /locus_tag="KRH23_002246"
     CDS             28110..28757
                     /locus_tag="KRH23_002246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside recognition domain-containing
                     protein"
                     /protein_id="HHS5225524.1"
                     /translation="MDVTAGDNKVTWKGYLSLFVLIVLFSGVFKDSQGFLKALDFANL
                     TGSFGTIADGVDFMGKGGTGAKDGFLFALTLIPTVCFAVGLIDVVESMGGMKAASKIF
                     NPLLRPLLGIPGIAGIAFVSSFTSSDVASIMTKELFESGEITDDERTIFVAYQYAGSA
                     VILNTINTQAPLLPIALLALGPIILIEIFCKILGANLVRLIIGVRNKKNKAKEAV"
     gene            28759..29268
                     /locus_tag="KRH23_002247"
     CDS             28759..29268
                     /locus_tag="KRH23_002247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjiG family protein"
                     /protein_id="HHS5225525.1"
                     /translation="MSQQNTGNAIVNSKPKKTAVEIFMGGAKKGFYIGVEQILPAMIM
                     GYVIVQFLQLTGLVDILGNIFGPVMGIFGLPGESVVVLIAAFFAKAAGAATAANLFAQ
                     GLITAPQATILIMPCMLMGTLVGHYARIVLVANASTKYRMLLLAVPIFDAIVGMLIVR
                     VLLTVMGLM"
     gene            complement(29632..30744)
                     /locus_tag="KRH23_002248"
     CDS             complement(29632..30744)
                     /locus_tag="KRH23_002248"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HHS5225526.1"
                     /translation="MKISEVATPNFLLDLDQLEKNIDKIQQICTNNNKQLWPMLKTHK
                     STYIARLQKNAGASGFLVGTLDEGEALIKAGFEDIMLAYPYMGEVNINRIVTMASKIN
                     LICATDNIECAKAYSEAFSKSKIECKLLIIVDCGLHRFGVEPEKVVELATEISKLENI
                     KIVGISSHPGQVYGCSSPEGVPDVCVQEDSSMEKAYKALTDNGFNIEIVASGSTPTVE
                     SEAASKTITAVRPGNYVYYDAIQIGLGCATEDMCALTVVCTVTSKNSSGYYLIDCGSK
                     CLGLDKGAHGNSSIVGYGRVCGHPELTIDSLSEEVGKIKVNGETDIKIGDRIRIIPNH
                     SCSTANLTSNLLGFRGDTIEKVIEVDIRENSKQIIL"
     gene            31108..31308
                     /locus_tag="KRH23_002249"
     CDS             31108..31308
                     /locus_tag="KRH23_002249"
                     /inference="COORDINATES: protein motif:HMM:NF013989.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008703 -
                     5-amino-6-(5-phosphoribosylamino)uracil reductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase family protein"
                     /protein_id="HHS5225527.1"
                     /translation="MVGGGDIVKLFMKDNLIDDYYIYILPIILGRGISLFKSGIDKTN
                     LNFKKASNIRELVKLEYSKKQK"
     gene            31553..33280
                     /locus_tag="KRH23_002250"
     CDS             31553..33280
                     /locus_tag="KRH23_002250"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHS5225528.1"
                     /translation="MKLILSYLKNYKLLIVLNILAIFSFALVELGIPTIIAKIIDNGI
                     ANQNIAYIKQMGIVIVIISIIGVVGSILLGYCSAKVSTSVTRDIRNDIFEKSQEFSHT
                     EYNKFGISSMITRTTNDAFQIQQFVNILLRTALLTPVMFIISIIMTIRTSVELSIVLA
                     ISVPFIIIGVAIIAKVSQAISSKQQKGLDKLNLISRENLTGIRVIRAFGNDDYETERF
                     EKTNTYYANVSKKLFKLMSITQPAFFLLLNIAVLAVFWISSEKINIGELQVGQLVAFL
                     EYLFHAMFSIMLFSMVFIMYPRAEVSANRIKELLNEEPLIKNPENGIKDTENKGIIEF
                     DNVTFTYPDGEASVLKDISFTAKTGETVAFIGSTGSGKSTLINLIPRFYDVTEGSIKI
                     NGVDIREYDLKALRKKIGFIPQKSLFFTGSIANNIRFGKHKAGESELEYSAKVAQAYE
                     FISKKPRKFDELISEGGANVSGGQKQRLSIARAIIRRPEIYIFDDSFSALDFKTDAIL
                     RAKLKKETKDAIVLIVAQRISSIIDADKIIVLNEGQVVGMGTHKELLKNCEIYYEIAT
                     SQLKKEELE"
     gene            33280..35070
                     /locus_tag="KRH23_002251"
     CDS             33280..35070
                     /locus_tag="KRH23_002251"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHS5225529.1"
                     /translation="MKKSKGFKKTIGRLLPFVKKYKFSFIIAIICIISAATMNALAPK
                     TEGLIITQLTKDVISIAKGVPGASVNFDYVTKILVILACIYFANAIFTYTSSFLLTNA
                     IQNTMRDLRNEVENKIRRLPISYFDSNSFGDVLSRISNDVDTISNALQQSFMQIVNSI
                     LVIILALSMMFTINIYMALIALFIIPISYFVSKFVVKKSQSRFSLQQNALGKLNGKVQ
                     EMYTGFNEIKLYGKEEDSIKEFKKVNQELCENGFKAQFISSMMNPMVSLVTYFGIAAV
                     AVVGSIYAVSGGITVGNLQAFVRYIWQINQPLSQMTQLSTVIQSSFAAIERVFEILDE
                     EEEIPDVENPVKIENVKGNVTFEHVNFGYGENSTLIEDLNAEVKSGQMVAIVGPTGAG
                     KTTLINLLMRFYDVKKGAIKIDGVDIRDMKRKDLRSMFGMVLQDTWLFNGTIFENIEY
                     GRFGATKEEIIQAAKVANVHHFITTLPDGYNMFLNEEASNISLGEKQLLTIARAFISD
                     PSILILDEATSSVDTRLELMLQKAMRNLMNGRTSFVIAHRLSTIRNADLILVMNNGSI
                     IEQGNHDELMEKGGFYEKLYNSQFADKESE"
     gene            complement(35232..35540)
                     /locus_tag="KRH23_002252"
     CDS             complement(35232..35540)
                     /locus_tag="KRH23_002252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5225530.1"
                     /translation="MFNKIYEKKEFIVFQVKKGYVVYNTRKSFEEGHTHLKHFEAAKT
                     AIDLAINKKIPRSKDGYYLTSLIRISDDGYYIDKLSELLYVREQKGKKEKYCNSGYQM
                     "
     gene            complement(35802..36350)
                     /locus_tag="KRH23_002253"
     CDS             complement(35802..36350)
                     /locus_tag="KRH23_002253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5225531.1"
                     /translation="MIFLNEDVVTNETIDKDYAIEEVRMACKHFGDLYFYFSKVLFEE
                     FGEDKTSEILRKVLFERSEERAIAMREKAHENGDELIADNIISTTDVPFLGWVPEFEE
                     LHCPYGASWLLRFEENPWFKKFASLYCDVTDTTVAEVFTGDTSHKITKNILWGDKSCE
                     RIYFHDDKVSEGKYTYGNKNCK"
     gene            complement(36453..37124)
                     /locus_tag="KRH23_002254"
     CDS             complement(36453..37124)
                     /locus_tag="KRH23_002254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HHS5225532.1"
                     /translation="MATFKRLQEQAYDYLKELILSGEMIENEIYSETKLASEIGISRT
                     PIRDALQRLSQDGFIDIIPSKGFRIHQITANEIVEIFQIRSAIEGFCTFLITSQYKEA
                     RAVETISKLKHLLDKQKDILLGDKNLNSFAEYDTLFHTTIVSYAQNTEFDKMFNNYMY
                     RIKKLALDSLSHEGRLETTLKEHTDIFNNIANGCIEDIYRTTLIHMETPKYINLEDFC
                     NNKLF"
     gene            37520..38425
                     /gene="garR"
                     /locus_tag="KRH23_002255"
     CDS             37520..38425
                     /gene="garR"
                     /locus_tag="KRH23_002255"
                     /EC_number="1.1.1.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008679 - 2-hydroxy-3-oxopropionate
                     reductase activity [Evidence IEA];
                     GO_process: GO:0046487 - glyoxylate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxy-3-oxopropionate reductase"
                     /protein_id="HHS5225533.1"
                     /translation="MEGYKMKLGFIGLGIMGKPMAKNLLKDGCNLLVYDINKSAVDEL
                     ISCGAKYASVLEMGQECDIVFTILPNGTIVQDILFGMDGLAKTLKEGSIVVDMSSVTP
                     TESILCANKLKDMGLEFIDSPVSGGEPKAIDGTLAFMAGGKEEIYKKVEPFFNIMGSS
                     SILIGDNGSGSVTKLTNQVIVNLTIAAVSEAFVLAAKAGADPEKVYKAIRGGLAGSTI
                     LDAKIPMIMNRDFKPGGKISINLKDIKNVMQTAHNLDVPLPMTSQLLEIMQTLKVHGH
                     LEDDHSGIAQYFEKLAGVEIKKHNN"
     gene            38561..39943
                     /locus_tag="KRH23_002256"
     CDS             38561..39943
                     /locus_tag="KRH23_002256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HHS5225534.1"
                     /translation="MITGYGLLIAFVISIGILLVSIIKFKVNPFLALLITSIITGFMV
                     RMPINEISTTISTGFGNTLGSIGIVIGLGIIFGNILSESRATESIAKGLLAKTGEKNS
                     ALAVTTAGFLISIPVFMDAAFVIMMPIIKYVSRVTKKSLMVFVCALGVGTIVGHALVI
                     PTPGPLAVAANVNANVGSFILYSIIVAFPAALIGGWIYGKRFEKYPAYAIDENDREKN
                     LEQGKDSIKIEEDDSSKVPGFGISMFSLLFPILLILISNVFSMFLEKGSTMSGVLAFI
                     GDKNIAILLGILVAIGFLKKYINKPMGDVVIEAADSAGLILLITGSGGAFGSVINASG
                     IGNFLVDTMSGLSISVVVLGFLLSALLRISQGSATVALVTTSSILGPTILATGMSPVL
                     VGLAICAGGVGFSLPNDSGFWVLSRFSGLSVKDTLNSWTIGGTIAGVVAFIMVLLLSV
                     INGIIPLPGL"
     gene            40014..41450
                     /locus_tag="KRH23_002257"
     CDS             40014..41450
                     /locus_tag="KRH23_002257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="four-carbon acid sugar kinase family protein"
                     /protein_id="HHS5225535.1"
                     /translation="MREVKPISIDILNTFKQVDEDRLNELLADELKHLDRKIVVLDDD
                     PTGVQTVHDISVYTDWDKDSMEQGFNEKNSMFFILTNSRGFTVAQTTKAHKEISKNIV
                     DVSKKVNKDFIIISRSDSTMRGHYPLETNLLKSEVERLSGKLFQGEIIMPFFKEGGRF
                     TIDNVHYVKEGEILVPAGMTEFAKDKSFGYKSSDIGEWCEEKTKGKYKSSDMIYISSK
                     ELRELNIEAITEKLKKAEGFNKIIVNATDYVDVKVFTIAFIRAVNSGKEFMFRSAAAI
                     TKVLGGVSDKELLTKDELVSKGNTNGGIILVGSHVNKTTQQLEELKNCKYPIEFIEFN
                     QHLVLQENGLKNEVKRVIKVVEEKISSGKTVAVYTRRERFDLDTNDKDKQLMISVEIS
                     DAVTSIIGMLNVRPNFIIAKGGITSSDVGTKALRVKKATVMGQIKPGIPVWMTGKESK
                     FPNMPYIIFPGNVGEISTLRESVEILMG"
BASE COUNT        16014 a         4810 c         7046 g        13705 t
ORIGIN      
        1 ataaaagtta ataactatac aagattgata aagaaaaagt caaaatagat aattgattag
       61 caaaatagat ataattataa tgaagttaaa tctagcaata ttctcctaaa attaaatttc
      121 atttatttaa ttaaatataa tttgacaatg ggcaaaaaag tgagtaaaat ataaataaaa
      181 taaaaataac aggttcggat aaagaaaaag gtttcttaac ctcaagcata aagtatatta
      241 tctaagttat ttgagattaa gagataaatc caatcttagg tactgaggag gaaaaaatgc
      301 ttgatataaa aagaataaga gaaaatttag attgtataaa aaaagcaatg gaaagaaggg
      361 gcgaaaaaga ctttaacctt gatgaagtag ttaagttaga tgatgaaaga agaaagattc
      421 ttcaagaagt tgaagttatg aaaaatgaat taaatacagc atctaaaaat ataccaaatc
      481 ttataaaaga aggtaaagat gtagaaaatg aaaagattaa actaaaagag ttatctgata
      541 aaattaaggt aatagaccaa aatcttaaag aagtagaaga taagatggaa tacctattaa
      601 tgagaatacc aaatgtacca catccagaag taccacaagg tgaaactgat gaagataatg
      661 ttgaagtaag aacttgggga aagactacta cctttgattt tgaatctaag gctcattggg
      721 aaattggaac aaaattaggt atacttgatt ttgaaacagc tagtaaaata actggttcaa
      781 gatttactct ttacaaagga ttaggtgcta gattagagag agcattatta aatttttact
      841 tagacacgaa tacaaaagta aatggatata cagaagttat tccaccattt atggcaaata
      901 gaaatagttt tttaggtaca ggacagttac ctaagtttga agaagatatg tttaaaatag
      961 aaggtctgga ctattttatg attccaacat cagaagttcc tttaactaat atacatgcta
     1021 atgaaatact taaatttgaa caattaccga taaattacac agcttatact ccatgtttta
     1081 ggtcagaagc tggttctgct ggaagagata caagaggttt agtaagacag catcagttta
     1141 acaaagtaga aatggttaaa atagttgcac cagaagaatc ttacaatgag ttagaaaagc
     1201 ttactaacaa tgcggaaaat atgctacaat tattgaatct gccttatagg gtagtaaaga
     1261 tatgtacagg tgatttagga tttacggctt cttttaaata tgatgtagaa gtttggatgc
     1321 caagttacaa taggtatgtt gagatttcat cttgttcaaa ctgcgaagat ttccaagcta
     1381 gaagagcagg aataagattt aaaagagata aagattctaa agctgaatat gtacacacat
     1441 taaatggctc tgggttagct attggaagaa gtgttgcagc tatattagaa aattatcaac
     1501 aagaagatgg ttctgtggtt gttcctgaag ttttaagacc atatatggga gtttctgtta
     1561 ttaaataaga gttaaattat gtatttttaa gcaatacaat aatatagagg taataaaaaa
     1621 taattaatat aaaagtgata cttctaatat agaagtaata aaaaaatagt taatataaaa
     1681 gtgatacaat aatatagaag taataaaaaa atagttaata taaaagcgat acaataataa
     1741 tagaagtaat aaaaaaaaat aattaatata aaaatgtgta caaactaatg aatattgata
     1801 tagtaagcta tcatatgaaa gagtatgtac acattttttt tactaatttt tcacaatatg
     1861 aacataaata atttacagga aaggaatctt ttatgaaaat tcaaaatact gaatggggat
     1921 atattgaatg gaaacatact tatgatgaaa ataatccaaa acaagctatg aatatataca
     1981 ttgcagtaac tatgcctggt aagaaacatt ttaatcatgt tcattatggt caagagcaga
     2041 tgatatatat tttagaggga gagggtttgt atattataaa tggagtttgg aagccatttt
     2101 atcaaggtat gattttttat atagaatctg gtagcacaca tgaaactata aatacaggtg
     2161 atagagaaat aaaagaactt attgtttcaa ataatgtaga tgatgtagga gagagtgaag
     2221 ttatagatat taatcctaat aattatttaa agaagacctt gataaattat agtgaaagta
     2281 cattaaattt gtatgcagca gtagaatcaa ttcgtggtca atttatagac ccgtttaaaa
     2341 ttccattaat tatatatgat gattcatgga atatagtttt aaaaaatcct tattttccac
     2401 ttttttgttt tgaaaaatgt aatcctatga aatttcctca aaattgtgat tgtatgaatc
     2461 aaaaaagtag caatcaattt gtatgtgaat atgggataac tatatataat ataccaatac
     2521 tgtacaaaag caatagcata ggtgttataa gaggagggta tgtactatta tctgatttga
     2581 atttagatac agagcataat aatttatatg atattccaga gggagctgct agaagtataa
     2641 aacgcctctt gaaacaaata tctaaaaata taataaattt ttgctctttt aatgatataa
     2701 gaaaggattt acaagaaaaa gagaagacta tagcaagaac atatcattat ggagagcaac
     2761 ttgaaatgaa tttaaaagta gctcaagata tggttactaa tttaagaata aatcatcact
     2821 ttttatttaa tacattaaat tcaatggcaa gcatagcact agatgatggt agttatgatt
     2881 tgtatagtgc aataatagat ttatcaagaa tgtttagata tacaatgagg tctgatttaa
     2941 gatttgtaga attagaatct gaaatattat acattaaaaa ttatttgaat ttacagaaat
     3001 tacgttatgg agatgcactt aaagtaaaat atcttattct agagaagtta tataaccttt
     3061 ctgtgccttt taactttatt caacctattg tagagaatgc atttacacat ggatttagag
     3121 atattgacac agaaaagcga attgaaataa ttgcaagatt agattctcag tatgctatta
     3181 tagagattca taataatgga actatcttag atggaaataa tatagacaaa ataaaggcag
     3241 gtattcgtag taataatggt catggtttgt ctttaatata tacaaaattc acatctgctt
     3301 atggaaataa ttttgatatg gatataaagt cgagtgataa tgaaggaact tacataatga
     3361 ttaaaattcc tattgaaaat tataaggagt atgtatagaa cttgtgaaaa attaataagt
     3421 tttataaatg ttaagaaata tattagatgt ttttatgttg ttttatatat tttacttttt
     3481 tatattatta agctaaaagg gaggtattct catgagaaga gcactaataa tagatgatga
     3541 agaagctgtt ctaaaaataa taacacattt tatagaaatg aaagatatgc caataaaaat
     3601 tgttggtaaa gcaacatctg gtgatgaagc agtagataaa atcattggtt tagagccaga
     3661 catagttttt atagatattc aaatgccaat atacaacggg ttagaagtaa tagaaaaaac
     3721 atctcattta tctaaaaaaa taaactttgt agtaataact gcatttaact attttgaata
     3781 tgctcaaaaa gctttgagat taaatgtaaa agatatactc cttaaaccat tggatatgaa
     3841 agaatttact aagtctgtag aaaaaattat tggatatcaa tataccaata atgatttatt
     3901 aaatgagata ctggaatata taaatctaaa ctatagcaat gacttaaagt taaatgattg
     3961 tgctagatta tttttaacca atccatctaa tatatctagg atttttaaaa gtaatttaaa
     4021 tacaactttt atatcatatc taaatcatat aagaatagaa aaatctattg agttacttga
     4081 aaatactaca aaaagtataa atgagattgc agaaatagtt ggatataata gcctaaataa
     4141 cttttataaa aactttaaga tagaaaaagg aatgactcca aaagtttata aactgaacac
     4201 taaaaattga aattgataaa taaaaagtca atatagataa ttgtttgagt gtgtctgaat
     4261 aagtatactt taattatgat aaaaattaaa gcgctttaaa catatttaat aatattaaac
     4321 cttataaaag ctgtacctat ttatataaaa aaatatatat aaataaaaag aaaaagatat
     4381 acaaaataaa aaaagtgaat taaatactgt ttcaaaaata cagaattttc atttaattta
     4441 ctgagagttt atatttctta aaggaaggta actttataat ggaggtaatt taatatgtca
     4501 gacaaagtga atatgaaaaa tattatctgt attgcaggcg cttacctagc aacagcaatt
     4561 ggttctgggt ttgctactgg tcaagaaatt ctacaatttt ttgcctcaca agggtatatg
     4621 ggtttaattg gagcattaat atcaatggta ttgttttcat ttcttggtgc tgaagttata
     4681 actagaggta gagaattaaa acttaaagaa ccaacaagaa tttacacttt ttattgtggg
     4741 aagattttag gaaaatttta cgaatggttt agtccaatat ttttatttgg gattcttata
     4801 gtaatgattt caggtgcagg ctcaacttta actgaatact atggtataaa tccttactta
     4861 ggaagagtat tgatggctgt tgctacttta attacagtgt ctatgggttt agaaaaatta
     4921 gtaagcatac ttggacgtat tggaccagtg atagcagtat ttacaattgc tgttggatta
     4981 ataagcttgt ttaagcattt tgatggttta tctatggttg gagaagctat gaaaaatatt
     5041 gaagttacaa aagcatcaga aagtccaatc gtttctggtg taatatataa tacattaaat
     5101 attattgtaa tgattgtttt tttaacagga atgggagctt ctattgaaag taaaaaggat
     5161 gctttttggg gaggtttatt aggtggaata gtgtttatga ctgctggtat agttatgtat
     5221 ttggctatga tttcagatat aggaaatttg tatatgaaag aaataccatc actttattta
     5281 gcagataata tatctcctat tgtaggtgta tgtttttcag ttgcattaat attaggtatc
     5341 tatacaacag ctgttccact tttatggtct gtaaccaata gaattgttga agatgaacat
     5401 cctaaattta aattggtaac aacagtaata gctattttgg cttgtatagg aggtttttta
     5461 ccatttggta aattagtaaa cattttatat ccatatacag gttatacggg gcttttaatt
     5521 ttagtctgta tggtgtataa agcaattaca tgtagaaaaa aatcaacaca aagtcaggaa
     5581 tagagccact tattaatagt ttttatttaa agaaattttt tatataatcc gaatttaaaa
     5641 agtcaaaata gttaaataaa ttgcaaaaca tgataatata tttaattaaa ataatatagt
     5701 aaaatataaa tataaactaa aattaaattt ataaaaaata tctttataaa gattattaac
     5761 ttatataatt tgtagttaaa ttataaaaaa taaaaaaata aaattttgga gaggtgttag
     5821 tatgcatgaa cttattttaa tctcagaaaa gtataaagaa gatattttag atttttttac
     5881 agatattcat atgcaccccg aattaagttt taaagaattt aggactacaa aagctataaa
     5941 agatttatta gtgagtttag acatagaaat attagattta ggaatggaaa caggagttgt
     6001 tggattatta aaagggaagt atgatggtcc cacagtagca ctaagaggag atattgatgc
     6061 attgccaata tatgaagagg ttgatattaa gtataaatcc agatatgatg gtataatgca
     6121 tgcatgtggg catgatatac acacgtcttg ccttgtagga tgtgcatatg tattgtctca
     6181 tattagagat agtcttcatg gaaatgtaaa gtttatattt caaccagccg aagaagtcaa
     6241 taaaggtgcg aagatgctag tggaacgagg agtaatggaa aatccaaaag ttgatgctat
     6301 atttggactt cataatcatc cagatatacc ttgtggaaaa ataggtgtta agttaggtgg
     6361 gttaatggca gcagtagaca ctattaagat agaagtaaat ggatttggag gtcacggagg
     6421 tataccaaac agaacaatag accctatagt agcatcaagt gcaattataa tgggtattca
     6481 aaccatagta agcagaaaca taagtccatt agaatcagct gttatatcaa taggtactat
     6541 aaatggaggg actgcaaata atgtaatttc agaaaaggta gatatgacag gcacatgtag
     6601 aagctttagt aatgaagtac gaaagaaaat atcagaaaat ttagaaaata tagtttgtga
     6661 gatagctcgt ggatatcaag caactgcaaa gctagattat ttatttgatt taccagctgt
     6721 tataaatagt aaagagatgt acgcaatagc ttgtaagtct gtgtgtgatt tgtattcaga
     6781 agatgctata gttgatccaa taccttctac aggaggagaa gatttttcta tattcatgga
     6841 aaaagcccca ggattttttt actggttagg ggtaggcaac aaagaacaag attgtatata
     6901 tcagtggcat aatcctaaat ttaaagctga taaaaattct atattggtag gtacaaatgt
     6961 actatgtcag tctgttataa attatatgga taaattaaaa aataaaattt aagatagagc
     7021 attctggaga taaagtttat gagggggtat tagtttgagg aaaattaatt cacaggaaaa
     7081 aaacaaagat agtggattat tgatgagggc actaaatgtt gtagagagag caggaaataa
     7141 acttccagac ccagtaacca tatttttatt actatgtata attgttgtaa tattgtcagc
     7201 agttatatct aatttaggag tagaagaaat acatccttct acaaaagaag ttgtaaaggt
     7261 agtaaatcta ctagagaaag agcagattca atcatattta ggtagcatag ttacaaactt
     7321 ccaatcattt gctcctttag gattagtact ggttacaatg cttggagcag gtgttgcaga
     7381 gaaatctgga tttatggaag tgttaatgaa aaagggtata agtaaagttc cacaaaaact
     7441 tgtaactgta gcaatcgtat ttgcaggtat gttgtcacat acagcagcag atgtaggatt
     7501 tataatatta ccaccacttg cagcacttgt gtttttagga attggaagac atcctcttgt
     7561 aggtatgttt gcagcttttg caggtgttgc agggggattt gcagcaaatg ttatgcttag
     7621 tactacagat gtattgttag ctggatttac aataccagca gctcaaatga tggacccatc
     7681 ttaccaaggc aatccagcaa tgaatcttta ttttgctttt atatcagcga tagttttaac
     7741 ttttgcagga gcatttgtaa ctgaaaaatt tatagctcct cgttttacaa aatataatga
     7801 ttcaacaaat gataaggata tacaggaatt gagtgaactt gaaaataagg gtataaaata
     7861 cgctttatta tcattgttag ttgtagtagt agtgatagtt gccttatgta taggtgacaa
     7921 tgcatttatg aaagatccag agactggttc tatactatct agtaatgcac ctttaatgaa
     7981 aggtatagtt cctataatca ctattatatt tttaactcca ggattagtgt atggaaaagt
     8041 aagtaagaag ataaaaagtg acaaagattt agtatctatg atgggtagta gtatgagtga
     8101 tatgggtgga tatatagtcc tagcatttat agcatcccag tttattaatt tatttaatct
     8161 tagtaactta ggaacaattt tatcaataac aggagcaaaa ttactagcag agtcgggaat
     8221 acctagctat ggattgataa taggatttat attgctatct ggatttatca atttatttgt
     8281 aggaagtgct tctgcaaaat gggcgatttt agcacctata tttgttccca tgtttatgct
     8341 actagacttt aatccagcat taactcaaat agcttatcgt attggagatg cttcaacaaa
     8401 tccaataagt ccactttttc cgtattttcc agttatattg gcctttgcca gaagatatga
     8461 taaagatata ggtataggta ctgtcatatc gaatatgatt ccatactcag tggtatttac
     8521 attaatagaa ataataatat tgttactatt catgggtatt ggcataccat taggacctgg
     8581 tggaggaata tcttacgttt tatagaccgt tataataaat ttatcaatga agattaaact
     8641 aataaaatat attctttaat taagaggagg attattatgt taaaaacaac aaaaatttca
     8701 gacccagagt tatacaagat tgtagctgat gagttggtta gacaagaaca caatattgag
     8761 atgatagctt ctgaaagtac agcaccaaca gaagtacttg aattaagtgg atgtgtattt
     8821 acaaataaaa cagaagaagg ctatccaggg gctcgttttc aagcaggttc tgaagaagca
     8881 gataaacttg aaaccctagc aataaaacgt gcaaaagaag tatttgaagc agaacatgta
     8941 aacgtacaac cgtattcagg ttctacagct aactattgtg tatattcatc aatattaaaa
     9001 ccaaatgaca ctgttttaag tatgcgtctt gaccaaggtg gacacttgac acatggtagc
     9061 gcagttaatt ttttacatga catttataaa tatgaatttt atggggtaga cccaaatact
     9121 ggacgtatag attatgatgc tcttgaagca aaggcaaaag aatgtagacc aaaacttata
     9181 attgcagggg caagttcata tccaagatta atagattatg aaagaatatc aaaggttgca
     9241 aaagaagtag gagcttactt tatggtagat atggcacatg ttgcaggatt agtcgcagcg
     9301 aaagtaatac ctagtcctgt accttatgca gattttgttt cttcatctac gacaaagact
     9361 ttctgtggac caagaagtgg tattgtactt tgtaaagcag aacatgcaaa gaaactcgat
     9421 aaaggtgttt ttccaggaac attagggtct atacatctta atacagttgc agcaaaagcc
     9481 ttttcactat tatatttaag tacagataaa tttaaaaaga taatggagca agttgtagta
     9541 aatgctcaga ctctagcttc tgaactgatt tcacatggtt ttagtattgt aagtggaggt
     9601 actgataatc atatagtaat ggttgactta agaagtaaga atcttacagg aaaacaattt
     9661 gaaaaagctc ttgaatatgt aggaataaca gttaataaaa atgttatacc tgacgaccca
     9721 caatcaccat ttgtaactag tggtgttcgt ataggtctta catcaatatc tcaaagaggt
     9781 ctgaaagaaa aagaagttat acagatagca gagataatga ataaggtagc agaaaatatt
     9841 gataataaag aagtattaga tgaatgtaaa gcagaggcac aagaacttat atctaagttt
     9901 ccattatatc cagaagggta ttttgaagat taaatatttt gatttgtata gctcacaatt
     9961 tataaagcct gtaacataaa atttaataat atataaccac tataaggtgt tgattaatca
    10021 acaccttatt ttttttgaaa agtaatatac aagctatcat aagcatataa ttccttatag
    10081 ataattaaca agggggataa agttatgagg tattataata aacctaccaa agaagtatta
    10141 aaatacttaa aaacaaatcc agaaattgga cttgatgata atgaggtaga agaaaggaag
    10201 cttagatatg gattaaatga atttactata aaagaaggta gaacattttg ggacgagttg
    10261 ggagaaagtt tgacagaacc tatgatatta attctcatag gagcagcagt aataagttct
    10321 tttgtgggag aattacatga cgcattaggt attttagggg ctatttttat tggaatttct
    10381 ataggcataa taactgaagg aaaatctaaa aaagcagctc atgccctgtc aaaattaaca
    10441 gaaaatatag aagtaaaggt acttagaaat gggaagataa ttaaaatatc aaaaaatgat
    10501 ttagtaccag gagatattgt atatatagaa actggggata tgataccagc agatggaaga
    10561 cttatacagt ctataaattt gaaacttaga gaagatatgc taacaggaga atctgatgat
    10621 gtagctaaga atgctgatgc tgtattagat atggaagtag tttattctaa aacagaaata
    10681 atcgaacagg atgcaatacc tgcaaagcaa gtcaatatgg tatttggagg gactcttgta
    10741 gcatatggta ggggcgtaat ggttgtcact catactggtg ataagacaga gatgggtaag
    10801 atagcacaga atttatcaaa tgaagaccag caaactccac ttcaaattaa attagggaag
    10861 ttgggtgcta aaatagcagg aatatcaggc ataatagcta ctttattgtg tatgtttatg
    10921 attatacaga tgcagagaaa aggtatgtta attttagata caagcagtat attatctttc
    10981 ttacaatcat tagaacctgc taaaaatgca tatatggttt gtattgcatt aatagttgca
    11041 actgttccag aaggtttgcc aactatgata aatattacct tagctataac aatgcaaaag
    11101 atggcaaaga taaatgcatt agtaacaaag aaagaagcct gtgaaactat aggttctgtt
    11161 tctgtaatat gttccgacaa aacagggact ttaacacaaa acaaaatgat ggtagaggta
    11221 gcatatgttg atggtaaata tataagtgga ggagagtatc aaagtaatag ctattttgaa
    11281 caaaactgta tagtaaattc aactgcagat atagaaaaag aatataattc atttaaatat
    11341 ataggaagcg caacagagtg tgcattactt ttatatcata atgataagaa ctataatgaa
    11401 atgagaaaac aaacgtattt gatatcacaa ataccattta gttcagaaga aaagaagatg
    11461 tcaacattaa ttcgtcaagg ggattcagat atattacttt caaaaggtgc tccagaagta
    11521 ttattaaaaa aatgttctta tgtacaacaa ggaaaaaata ttgttccaat aactccaaaa
    11581 gtagaaaaaa gtattttaga tgagattaag aagttacaaa ttaaatctat gagaacatta
    11641 ggatttgctt ataaaaaaat gagtaattct aaaacagaag ttgcaatgac ttcagaaggt
    11701 gaattgaatt taataggaaa ttcaagaagt tatatgaagg aagataattt agtttttagt
    11761 ggatttgtag gaatagtgga cccattgaga gaaggggtca aagattccat tgataaagca
    11821 tttaatgcag gagtagatgt aaaaatgctt acaggagata atataaatac agcaacagct
    11881 attggaaatg aattaggact attaaatgat gggaaaaagg cagttgaagc aacatatata
    11941 gatgtattga cagataaaga attgagagaa gaaatcaaag gaatatctat tgttgcaaga
    12001 agtaaaccag atacaaaaat gagaatagtt tcagcacttc aaaaaagtgg cgaagttgta
    12061 gctgtaacag gtgatggtat aaatgatgcc ccagcactta gtcaagcaga tgttggaatt
    12121 gcaatgggta tttcaggaac agaagtatct aaaaatgcag cagatataat attgactgat
    12181 gatagcttta gtactatagt agagggaata aaatggggaa gaggtatata tgagaacttt
    12241 caaagattta tacagtttca gcttactgta aatatagtag catttataat tgctataata
    12301 tctcaactta ctggtaagga tatgccattt actacaatac aattattatg ggtaaatata
    12361 ataatggatg gtcctccagc cctagcatta ggattagaac ctgttagaga ttatgtattg
    12421 aaaagaaaac caataaatag acattctgga ataatagcta ggtctatgtt tgtaaatatt
    12481 attataaatg ctattcttat aattacaatt gtatttactc aatcagcttt taatatattg
    12541 ggagctacat cagaagaaca aggtactgtt atattttctt tatttgcatt cagtgccctt
    12601 tttaatgcat taaattgtag agagtttggt ttaaatagta caataccaaa tttctttaaa
    12661 aataaactgg cattgcaaat aatagtagtt acagggataa ttcaaataat atttacacaa
    12721 gtgttccaga gtttctttaa ttctgtttct ttggactttg atatgtggat aaagataata
    12781 ctatttgcat ctactatcct attatcaaat gaatttgtaa agctaattct tagaacaatg
    12841 aaaaatagta gaactatgaa ctttaatagt aaaaattaat tcttatgaaa ccgcaaagta
    12901 ctatatattg taactttgcg gtttttgttt gtttaatgtt gttttatatt accattttca
    12961 tatttaattt tttattaatc tgaacacaat cttccattgt aattgcttca tctgtgtcaa
    13021 cacattcaaa gtcaatatct aatttttgta atattttgta tgcctctttt tgcaaaggag
    13081 tatcaaattt aataggtgat tttgtgtaaa tatcactgat aaaaaacatg atttatttca
    13141 ttcacttcca tttaaaatct tatagttata gtgtatcata aggttataaa atatagataa
    13201 atatagtata aatttaaaat atgtacagac aaaacaaaaa aatcatattc taagtaatac
    13261 ttgggaaaaa tgatattatc ataataaata atctttgtaa aaacttatat agaatctatt
    13321 aaacagacac taagccataa aaactttacg aaatataaaa ttcgtatcta aatagatata
    13381 tagaatgata ttttactgga gtagagtgat ttttaagaat tttatatata aattatgtta
    13441 tcataaataa agatatagat tataaaattt gttaataaaa taaagggcag ggaggtaagt
    13501 ttaatgtttt ccaaaatcct agtcaaaaca tttatcagag atagcgaaaa cgttcaaaat
    13561 acagatgtta gaaataagta tggttatgta gctggtgtag taggtatatt atccaattta
    13621 cttttatttg tgataaaggt attcatagga atgctcacat ctagtatagc tataatggct
    13681 gatgcattta ataatctttc tgatatggca tcttcagcaa taactatgat aggttttaaa
    13741 ttagcaagta agccagctga taaagaacac ccttttggtc atggaagaat agagtattta
    13801 tcagcattaa tagtagcatt tatggtgatg ttggttggac ttcaatttgt aaagtcatct
    13861 atagaaagga tagtaaatcc aattcctgta aaatttgaag taataccact tatactttta
    13921 attgcatcta taatgattaa aatctggttg agtcgtttta ataaatttat gggaaataaa
    13981 attgattctt cagccttaaa agcagtttca cttgatgctt taggagatgt atttacttca
    14041 agttgtgtag ttatatcatt tattgtagct agatttacta attttcccat agatggatat
    14101 gttggtatcg tagtatcatt agtgatactt tatgctggtt tctctcttgt aaaagatact
    14161 ataaatcctc ttttaggaga agcaccggat gaagaaatgg taaattctat tatagagcta
    14221 ttgttatctt ataaatatat aataggtaca catgatttaa ttattcataa ctatggagtt
    14281 ggtagatgta ttgcatctat acatgcagaa attccatcca atatagatat aatggaaata
    14341 catgaaatta tagatactgc agagagagaa atatctgaaa aattagatat atatctagta
    14401 attcacatgg acccaatatg tcttgaagat aaagaagtta tgtcagccaa aaaagaactt
    14461 gaagaaatac ttaagaaaaa tagtcttgta aaatctatgc atgattttag aatagttgga
    14521 aaaggaagca agaagaattt aatatttgat atagtagtta atccttccga attttccaaa
    14581 aacatgtcag aagatgactt aaaagaagat ataacaaaat tagttaagga gataaatcct
    14641 gaatataatt gtgtaattgt tgtagataag gattttattt aattattaat taatctcatc
    14701 ataaggtaaa aaatgtaaaa aggatagaca atagtataga ggcataatat aatagaagta
    14761 tataattgta tttttaatat aaataaagca attttaattg tttttatgaa atattataga
    14821 gatgttgaag tatattctat tattgggcac cttatggata tactgagtca gtggtgcaac
    14881 cggctatgaa tataaattta tttattttca tagctttttt tgtataattt tttagtaaaa
    14941 attactttat atacgatatt aatggaagat tagattataa attataggta acctaaaggg
    15001 gtgagattta catgaagaaa ggaaatagaa aggcattatt aattagttta attatgattt
    15061 taagtatggt ggtgtctaca atatatccaa ctgtatctta tgcttcagaa ttaggagaga
    15121 atagtcagat tcaaagtggt tcaactaatt catcaactgg agaggagaag gaaagcgaca
    15181 ataaaaagcc agaacagact ccagagaaag ataaggcaac agataataaa aaaccagaac
    15241 agaccccaga ggaagaaaaa ccaacagata ataaaaaacc agaacagacc ccagaagaag
    15301 ataagtcaac agataataaa aagccagagc aaactccaga aggagaaaag ccaatagata
    15361 ataaaaagcc agagcagata caagaagaag ataagtcaac agataataaa aagtcagaac
    15421 aagctttaga agatgaaaaa ccactagaca ataaaaatac agaaaaaact ccagaggaag
    15481 ataatctatt agaagatgaa aatttattga aagttttaga agaagaactt aatgaagaaa
    15541 atgaagacta tggatttgtt gtaaaaatta ataacaatac aatagaaacg gaatcaatga
    15601 aaaaaatatc atttaattta acttatactc caacatcaaa aggaatacaa gcaggagatt
    15661 caataacttt taaggtgcca gatgtattca ataaagttaa tttagattat acaagtgaat
    15721 gctttgataa aacagaaagt aatggagagt atacacttac atttagagaa ttacctaatg
    15781 gccaaagtgt aatgcaaggt aaaataggtt tggaagcata tgttaaaaag gttgatgaag
    15841 atactaatgc aaaaatacat attgaaacta ctggaaaaat agaaagtgga agtggagata
    15901 tagatgtaga aataaaacct ggagataaaa cggatgttcc agatgctaaa ggaatactta
    15961 aaaagcttgt tgaaggaaaa aaatcaacta ctgtatttat gccagttaaa aataaagata
    16021 taaattacag tatacaagta aatgaaaagc aggaagagtt aaaagatatt attttgtatg
    16081 atgagcttcc tgaaggattg acattgataa atggttctgt aagtgtagta acaagtgatg
    16141 gaaaagaagt tagtgatttt aatattgaac agagtaaaaa ttctatttca gttaattttg
    16201 gaaatataga taaatcgtat actgttaagt ataaggctag aatcagtgac aaaaatgcaa
    16261 aacatggtaa taaatataag aatgtagcta ggattgaatc tgatggtaag aagatacaag
    16321 aagatgatgc tactgtaagt atatttgata gaggagatga ttatcttctt actaaaggac
    16381 attcaggagc aacaaatatt actcaagttg gtcaagtaat aaactatcag atttcaataa
    16441 atgatgataa atcaccaata agtaatgttg ttataacaga taatatacca gaaggcatga
    16501 gattaactac ttcaggagaa gctgggcatg attttagagt tgtagaaatt ccaatgaatg
    16561 ggagctggac tccttggagt aaagaaaaaa ttgccaataa tatttcatat gaagtagaag
    16621 aaaaaagaaa tgaaagtggg caagtagata aagttataac tggatttaca attaatctca
    16681 gtaaagaaga agtggaatca aagtttttta tagcttatac attaaaggta attagtattg
    16741 aagatagcta tataaataga gctgttcttg atgcaaataa tagtgaaatt gataaaaatg
    16801 atgagataaa ctttaagaaa aattctggat taataagcgc aaaaaaagaa gttgataaaa
    16861 aagttttaaa tagtagtgat aaccagattg ttaaatacaa aatcaatatg tcaacttatg
    16921 gggtttatga tgcaggacaa gtaaatcttt tagatgaagt aaactcagct ctagaaatat
    16981 ctaatataaa atattctgat aatcttgaac ttaaaaaaga agctggagat ggaaaaaata
    17041 caataagatt agtaaataaa tacgaattta aacagataaa agaaggggaa cctgtgcaaa
    17101 gttgggttac atttgatgca gacttcacaa atgtaaaagt tggggagact atacaaaatg
    17161 tggctcagat taatggttca agtcctccag gagtagagac tactaagcaa ggttatgctt
    17221 ttgaagctaa aaaagtggat gctttagata aaaatgtact ttcaggtgct aagttcaatt
    17281 tagaagatgc atttggaaat atagtagtta aggatttagt tagtgatgaa gatggtataa
    17341 ttcaatctag tataaaaaaa ccaggaacat attatttagt ggagataatg gctccaagtg
    17401 gatatgaaaa actgaaggat aaaattaagg ttgaaattgg taataaagat attggtagaa
    17461 tagtggatat tggaaatata gaaaacataa gacaagaaaa tccaccagta aatccaccag
    17521 caccaccaaa tacagatgaa ccaatagtaa atccaccagt accaccaagc acagataaac
    17581 caaggaaacc atcaagttca tctgatacag aggatactat agttataaat ccaccagtac
    17641 caccatcaga agatataata aatccgccaa taccagaggt attgaatccg ccagtaccac
    17701 catcagaaga gatgatagaa actcctgtta aacagattat tccaatacca gaagtagtaa
    17761 agccatcagt gtcagaagaa aaaaataata aagttaaaga tgatactttg gtaaatccac
    17821 cagtaccacc aaaaacaggg gatagtacta caattattgg agaaatactt ttggttatag
    17881 gagctattgt aggacttatc gtattaagaa gaaataaaaa tacaatttag accctaacat
    17941 tataaaaata taagttatat taaaaaatat cttctaaaac aatatttaat aatgaaaata
    18001 ttgttagaag atattttttt ttgaagattt atgtaaaaaa ataataactt tttagaaaaa
    18061 agttccaaag ggatatagac aattaaaaag atataagcta taatatagat ataaaattaa
    18121 atgaggcaaa actagggaaa cctagtcacg caaagctata ggggctaaag tttagtaaac
    18181 catgccagcc agttgccgaa aagagtaaaa atttcttttt gtatatacaa agatactctt
    18241 gggtatcttt tttattttga aatttattac tcccggccta actcaaagga gggaataata
    18301 tgagaccaag taaaaaatta ttaatagcta taatatcaat attcttaata agttcagttc
    18361 cagtaagtgc acatgcagat agtactacta tacaacaaaa taaagacaca cttagtcaaa
    18421 tagtagtttt tccaactgga aattacgata aaaacgaagc taatgctatg gtaaatagat
    18481 tagctaatat agatggaaag tatttaaatg cattaaagca aaataactta aaaataaaat
    18541 tattaagtgg aaagttaaca gatgaaaaag aatatgctta tttaaaaggt gtagttccta
    18601 agggatggga aggtactgga aaaacttggg atgatgttcc aggtttaggt ggaagtacag
    18661 tagctcttag aataggattt agtaacaaag gtaaagggca tgatgcaata aatttagaat
    18721 tacatgaaac agcacatgca atagaccata tagtattaaa tgatatatct aaatcagcac
    18781 aattcaaaca aatatttgct aaagaaggtc gttctttagg taatgtaaac tacttaggtg
    18841 tatatccaga agaatttttt gcagaatcat ttgcatatta ctatttaaat caagatacaa
    18901 atagtaagtt aaaatcagct tgtccacaaa cttatagctt tttgcaaaat ttagctaaat
    18961 agagttttaa taaatttaaa ataaatataa aagagatgct attataatag catctctttt
    19021 atattgcgtt taaatctaat aaattttgtc ttatgtataa ctatgataga ttatcaatta
    19081 ctactcctta tacaaggctt caacgtgttt attatgcatt tgagtaatta tcgtaggtat
    19141 aatagaaatt attgaaccaa ttactatcaa taaaattcct ataaccatgt ttatagggat
    19201 aatttcttta agtattaata atgctagtat tggagatatt actggtttaa agaagaatac
    19261 taaagatgta agactagtag atgtagcttc cattgccata aagtaaagcg cataaccaac
    19321 acctgtaaca aatacgaata cataaatcat aatgggcata ttgtgtaagg tatatccact
    19381 aaaaataggg atatttgcaa atacatgaag cttattttta tttaatatat ctgcgataaa
    19441 attaatttta gtgagtaaaa ccaatatcaa catttccaaa ctaccaaata taaagctaaa
    19501 gcaggttaca actattccac caaattttaa ggtttttctt ttaccaaata cagtatacat
    19561 tgaaaaaata atagcagaag ataatgttaa gaatattcca ctaagagtta gttttgtatg
    19621 caatggattt attataacta taattccaag aacttctaat ataagtgaaa ttacattgtg
    19681 cctatatatt ttttccttca aaattaagta agctaaaagc attacaaaga ctggattaca
    19741 actgaacaaa acagcaacta cagatgcctt tgtgtttaga acagcaagtt gatacaatga
    19801 catacttact actacacaca taaaacctaa aaatgcaaag tattttaagt ctgattttgt
    19861 aatagaaaga ctaagagctc ttaatctttt tacagcaaaa ggtagtaaga ctaaaccgcc
    19921 aacaaaaaat cttgataaag ttatttgtaa gggattaaag tcattagtga cagtttttag
    19981 actaatttcc attgaactaa aaaataaggt agtcagtatt atataaacat aacctttttt
    20041 caagtcaaac acctccttgt aatttatatt agtactatag ataagaatat tcaagcatat
    20101 tggaataata tggtatgtat aaaatatagt acataaaatt ataaactacc ttaatataga
    20161 atgtaagtat tctatactaa ggtagttaat tatttgaatt actttgattt agttatttta
    20221 aattatataa tttggctaat ttttcaaatg ctggtaaaga acttttaact ttatcataag
    20281 atacacaata tgatactcta aaatgacctg gacaaccaaa agaagaacct ggtactaata
    20341 ataaattaaa ttgttttgca tcattgcaga attttttatc atcttcaatt ggagcttttg
    20401 ggaacaaata gaatgtacca ttaggtttaa cacaagaata tcccatatcg attaaactat
    20461 tatatagaag gtcaaaattc tttttataaa tatttacatc aacttctgca tctaaacttc
    20521 ttgcaataac cctttgaaaa agagaaggag catttacaaa tccaagtatt ctatttgcaa
    20581 catttaatga agacataaca tcatcaaaat catccatttg cccattagca acaatatatc
    20641 ctatacgttc accaggtaga gataatgatt tactataaga gtatcctata aatgaatttc
    20701 tatagtattt tagtacacaa ggaactttgg caccatcata aattatttct ctatatggct
    20761 catcagaaat taggtatatg cttgtattaa attctttttg ttttgaatcc aataattctc
    20821 caagattttt taataattct tcagaatata tgacaccagt aggattattt ggagtgttta
    20881 ttattaaagc tcttgttttt ggagtaatag cattttttag agcatctaaa tctggttcaa
    20941 aagtctctat atttgtagga acttctatta attttccatc atagttttct gtataatttt
    21001 tatactcacc aaaatacggt gcaaaagcaa taacttcatc accaggattt aaaagagttt
    21061 ttaaaataat atttagacca ccagcagcac cacaagtcat aattaaattt tctcttgtaa
    21121 gatttaatcc atctttttta tttatgtgtt cagcaatagc atctcttaca tcctcatatc
    21181 ctgagttgtt catatatcca tgaactaaat ttggagattc ttcatttaaa atatcattta
    21241 taactgcttt aatagtctct ggaggttcaa cacttggatt tcctatacta aaatcaaaaa
    21301 cattttcctc accataaata tcagaaagtt tctttccttc ttcaaacata gctcttataa
    21361 cagaactatt tgcaactaaa gtttgcattt tattagatat catatgtaac actccttttt
    21421 atagatttat attgcttatg tatatattac catattttta ctgaatttag acaattttcg
    21481 aaaaattact tgtttgaaaa tataaacttt tatataaaat atatttatgt acagtgcata
    21541 ttaaaaattc caatttctaa ttttatcatg attattttat ataatagttt tttaaagaat
    21601 taataaaaca tagatttaga gaataaaata ttcttgacta tattaattgt ttaatataat
    21661 atagttgata tagtcaaaca tattataatt atagaaggga aatttaagat ggattttaaa
    21721 aatttacagt atgaaagttt gtcatatatt atttgtaact tgcaaaaaaa ctttaaactt
    21781 tattgtgaaa aatgtttaaa accatataaa cttacgaatg gtctatattt ctatttaatt
    21841 tatattaata aaaataggaa ttgttcttta aatgatgttt ctacagaatt tgaagttgat
    21901 aaagctcata caacaagaac tatatctagg ttagaacaag atggatacat agaaaaaatc
    21961 caaaacccta atgatagtag agcttttcag ttgagagtaa cagataaggg tgaggaagta
    22021 ttaggggata taaaaaacat attttcaaag tgggataacc acataaaaaa agagttctca
    22081 gataaagaat ataaagaact ggtaaagaat ttacatgtgg taaaggatat aaaaacagct
    22141 gtggaggaag aataggatgt attgtaattt attaaaacca attaaaattg gaaatttgga
    22201 attaaaaaat agagtatctt ttgcacctac aagcatgggt cttaaattgg aagaaaaaat
    22261 taaaaagttt tctgatattg ctaagtcagg agtagctctg attactctag gagatgtatc
    22321 tattagacct agttttcata aggtagctat aagcctatcg gatgaagatg gagtcatgaa
    22381 atacaagaaa attgtagatg aaatacacaa ttctggtgca aaggtatcag cacaactatt
    22441 ttgttcagat tatgatgtta atttaattaa agatactatg aatatgggaa ttacttcaca
    22501 tgatgagata aaaaaaataa tgaatgacgg agtaaaagat tacataacaa atatgcccaa
    22561 agaagaaatt aaaaatatta taaatttatt taaagtaaca gcattgaatg caaaaaaagc
    22621 aggttttgac atgattcaaa ttcatggtga taggcttgta ggaagttttt catcaagtat
    22681 atttaataat agaaatgatg aatatggtgg aacgtgtgat aatagaagta gatttgcaag
    22741 cgaaataatt agtagtatcc gagatgaagt taaggacatt ccaatagact ataaatttgc
    22801 aataagacaa gaaaatcctc attatggaaa tgcaggagtt ttactttcgg aagttgagta
    22861 ttttgttaaa aaatttgaat ccctaggtgt aaacagtttt catgtaacac ttgcaaatca
    22921 ttcaaaatta gaagatacta taccaaccaa taatcatcct tactttaaag aagaaggctg
    22981 ttttttatat ttagctgatg aagtaaagaa acacacaaat cttccagtat gtggggttgg
    23041 aaaattgtct agcccagatt ttatagaaag tattatttca aataatagag tagatatggt
    23101 ttctatgtca agacaattac tagcagatag taattggtta cagaaagtaa aagatggaag
    23161 agtagatgag attaaaaagt gctgttattg taataagaag tgtgcagatg ctttacaaac
    23221 acgctctcag tttggatgta tactagatta gaatatcctt ataaaaataa ataatttgtt
    23281 aaggttaata tatttttggt gatttagata agtatttaga taaagaggag gagacatcat
    23341 gaaaagttta gttttatatt caagtttaac tggaaatact aaaaagattg cttatactat
    23401 atatgatgaa attcaagaag aaaaagacat taaagatgta aatgaattag ttgattatag
    23461 tattgactat gaaaattatg atatagtatt cttaggctat tgggtggaca agggaatttg
    23521 tgataaaaat tcaaaacaag tgcttgaaaa tattcacaat aaaaagatag cactatttgg
    23581 aacaatggga gcaagtaaaa aaggaagtta tggagctagt ataatagaaa agatagaatc
    23641 aattatccca aaagataatg aaatattagg ttcattcata tgtcaaggta agatagcaga
    23701 aggattgaaa gcaaaatata aagagatgtt aaaactttct cctgacaacg aacatattct
    23761 ccaacaatta aataaccatg aggaatctca aagtcatcca gatgaacaag aaatatatga
    23821 agctagtatg tttgcaaaaa atatgatgat taaagctagt attgtgtagt agttaaacaa
    23881 taagttcata taagatatag aataaataat ttagtaaaaa agtatagcaa ataatttgct
    23941 atgctttttt tatgaaatca aaaaaataat aaaaatactt gactgtaaac cttgtttata
    24001 cattatttta tagaaaataa gatagtttta aatataaaaa aagatatatt attgaaagga
    24061 gatattattg tatgaaaact tataaaagat aattagtttg attttaagat atactaaata
    24121 tacaatttta tagagtgaaa atatttaaga ctatattata gttataaatt aatagaatag
    24181 agaggtagtg tttaaaatga caattaaaga agttgaagaa aaaacaggat tgacacgctc
    24241 taatattcgt ttttatgaga acgagaattt aattaaaccc cttcgtaatg agcgtaatgg
    24301 ctatagagaa tattcagatg aaaatgtaga gaacatcaaa aaaattgcat atttacgtac
    24361 attaggaatt actattgatg acatccgtaa tattatatta caaaaagtat ctttagttga
    24421 agttgtagag aaacaggaga aagttctcga aactaaaata tcagacttag aaaatgcaaa
    24481 aactatgtgt aataaaatgc tagaatctga tgagctaagt tatttgaatt tgaaagtaga
    24541 gcaatacata actgagttgc cagaatactg gaataaaaac aaacctgttt ttaaacttga
    24601 ctctgtaagt ttcttatata tatggggagg gaaaattacc tggggaatta ttactattgc
    24661 ttgtttgttg attgcaataa cagtatttcc aaagttgcca cctcaaattc ctatccaatg
    24721 gaataatggt gtagctaatt atgtagataa aaaatttatt tatgcctacc ctgtcatttg
    24781 tgttgtattc agaatacttt tacgtccatt tatatggaga tggttacaaa tacatgcttt
    24841 ttatagtgat actattgcag attatttaac gaattttatg tgttttgtag cgttgtctat
    24901 agaaatattc tctatacttt ttatttacaa tattgccaga catgttacaa taattatttt
    24961 tatagatata cttgtattta ttgctttact gataataggt gtgtataaat tatttaaaaa
    25021 atacaattaa tttttaaaaa taagtaataa gtgatagtgt aaaaagtagc cactgcaaat
    25081 tatggattgt agtggctatt ttattatttg tatatgaaat tattttgttt ttctaataag
    25141 ttacgatata ttatggttta tttcactgat aaaaggttta ggtattttaa agtaaaaagt
    25201 tgtatattct aataaaattt aaacattttg attctttaaa attagagaaa atacattgct
    25261 tttattaaaa aattaaatat taagaattta atttctgcat cttatttaga aaagataaga
    25321 aatcaacttt atatattttt ttgggccttc ctctttgatt atcgagtttt gtatttacaa
    25381 tagttgcaat tcctgcttta tataagatac tcaatattct attagcactt ctaagagtta
    25441 tgttcatata gtctgataat atttctgctg acacattatt tgaatttcta tcattaatca
    25501 tacacatgat tttagataca tttgtattag atagaggtat aaaagaagca actttattgg
    25561 ctattgagct atcttcaata ttattagaat ttttatttga atataaaggg cctattgtat
    25621 cattagtatc atttactata aaagtacagt ttccattcaa agaagcagat ttaccattag
    25681 cttgacgagc attttgctct gcatgaatat ttgtatttcc aatgccccaa cctatattta
    25741 agctatattt aatttctttt aaatcttctg aaataaaaaa atctgtatag ttattggtca
    25801 tattgtttaa catttcttta gtagtgtgta tctctatttt catatcattt tttttgacct
    25861 gaactccata aaatccatgt cttgatagag aatttaatat agtgttatat atttgatttt
    25921 gtatctcatc atttttaaat atcaaatctt catttatgta ctctgaacta tttactgtaa
    25981 ctatacaagt tgcagattta tttttgtcta agttttgtaa tgttatttca ttcaccagag
    26041 atttaaatgt attcaggatt gattctgtag atggaaccat gtaaatacaa tcatatccaa
    26101 gtttattaag ttcacaacta atgatgtaat ttctagtaaa agaaaggtta atcttattat
    26161 ctcgcaataa gtctaaatgt atttccaata atttatcatt taatttttta aagtcatata
    26221 caggttgagg gatattaaaa tctttaattg tatatggaca tttattagag tctattaatg
    26281 aatatatatc ataataattg ttgtcctctc ttaaaaaatc cataaatgat tttgtaaagt
    26341 caatatcttt ttggctattt aataatttga ataagtattt ataaaaatct ctttcatcaa
    26401 gctttaaaaa atttaatgga acttttatgt cttttatatt tattataagt tcactatatg
    26461 gaactatacc actgcataca aatccatcaa aattatctac ttgctcatag tatatattag
    26521 gtaaattatt aaaaggattc tcccctttga gctcaataaa tgtaatttca caagtatcat
    26581 ttaattcttt aagagcttgt ttaaacttat ctgacataaa ataagatgtt gtcaaaaaac
    26641 caattttata tttcataaaa cctcctttaa aatttcgaga gtattgtaac taatcaatca
    26701 atttataacc tcattttata atagtagata aaacgcgtca atttatttta caaaaggaaa
    26761 attgaaagaa aaatcagaaa atataaaaaa gactgaaaaa tatgttgact gtcaagaata
    26821 attgtgctat tttgtaatta aggactagtc ttttaagatt tcctaaaata aacttaggtt
    26881 ttaggaaaga aatacatttt atttgaaaat aaaggagaag attatgaata catatttaaa
    26941 tgaaatttct aagtttgttg atgagaatag agaagaaata gtttcattat ggaaagagat
    27001 tgttaatatg gaaagctata cacattgtaa agaaagcgta aataaattgg ctaagagatt
    27061 aaagtttgag tttgaaaaag aaggtttaga ttgcgaatta gtagatgttg gagataatgg
    27121 tagtacattg ataggtacac ttggttctaa tataaataaa aagcctataa ttttttcagg
    27181 ccacatggat actgtctttg aaacaggtac atttggagag aatccattta aaataataga
    27241 aggaaaagca tatggcccag gtgttttaga tatgaagggt ggtataataa tttccttata
    27301 tgttattaaa gctttaaata aaataggata caaagaaaga ccaataaaaa tagtattttc
    27361 tggagatgaa gagataggac ataaggattc aacaggtgca gatgttatat tgagggaagc
    27421 aaaaggtggt ctttgtgctt ttaatatgga aactggatta gtagataata gtttgtgtgt
    27481 aggtagaaaa ggaagaatcg gatgtaatat acatgtaaaa ggtgtagaaa cacacgcagg
    27541 taatgatttt gaaggtggaa gaaatgctat agaagaaatg gctaataaga tactacgcat
    27601 acaaaaattg actaatttag atgttggaac tacagtaagt gtaagtgtga ttaagggtgg
    27661 aagagtggaa aattctattc cagaagattg tagtataaaa gtagacctta gatttgaaaa
    27721 agtagaagaa atggagaatg ttaaagaaca agttagagag atatgtaaag aaacttacat
    27781 agaaggaact tctacagaag ttaattttat aagtgaaatg atgccatttg aaactacaga
    27841 agatgttatg agatttcata catttgtaaa tgaagtgtca aaagaaaatg gatttggaga
    27901 attaaatgct aagagacttg gaggtagttc agatgcaagt tatttaacta ttgcaaacgt
    27961 tcctacaatc tgttcatttg gtgtaagagg ggaatggaac cacacatcaa gagaatatgc
    28021 agtagtagat tctatgtttg agagggtgaa attaatttct acagttattt taaacttaga
    28081 taaatttgag gtataaaggg ggattttata tggatgtaac agctggagat aataaggtaa
    28141 catggaaagg gtatttatct ttatttgtat tgatagtatt attttcagga gtgtttaaag
    28201 atagtcaagg cttccttaaa gcattagatt ttgctaatct gacaggttca tttggtacta
    28261 ttgcagatgg tgtagacttt atgggtaaag gaggaacggg agcaaaagat ggtttcttat
    28321 ttgctctgac tttgattcca actgtctgtt ttgctgtagg tcttatagat gtagttgaat
    28381 ctatgggagg aatgaaagcg gcatcaaaga tatttaatcc attgcttaga cctctgcttg
    28441 gtatacctgg aatagcagga atagcatttg tatcttcatt tactagttca gatgtagcct
    28501 caataatgac gaaagaatta tttgaaagtg gggaaataac agatgatgaa agaactatat
    28561 ttgtagcata tcaatatgct ggttcagctg ttatactgaa cacaataaat actcaagctc
    28621 cacttttacc aatagcatta ttggcattag gtccaataat ccttatagag atattctgta
    28681 aaatacttgg tgctaatcta gttagattaa tcataggtgt aagaaataaa aagaataagg
    28741 ctaaggaggc tgtgtagtat gagtcaacaa aatactggaa atgcaattgt aaatagtaaa
    28801 cctaagaaaa ctgctgttga gatatttatg gggggagcaa aaaaaggttt ttacataggt
    28861 gttgaacaga tattaccagc catgataatg ggttatgtaa tagtgcagtt tttacaatta
    28921 actggtttag ttgatatttt aggaaatatt tttggaccag taatgggtat ttttggacta
    28981 cctggggaat ctgttgtagt tttgatagca gcattctttg ctaaggcagc aggagcagct
    29041 acagctgcaa acttatttgc acaaggtcta atcactgcac cacaagcaac catattaatt
    29101 atgccatgta tgttaatggg tactctagtt ggtcattatg ccagaatagt gcttgtagca
    29161 aatgccagta ctaagtatag aatgttactg ttggcagttc ctatatttga tgcaatagtg
    29221 gggatgttaa tagtaagagt tttactcact gttatgggat taatgtaaat aacataaaat
    29281 tataacctaa ctataaatga tatataagaa ttaatatata caaggattaa tgagtagtaa
    29341 ttgatatata gtaataaact aagatagtaa ttaatgtgta tattaattaa aaaaagagag
    29401 tatctcaaag tgaacttttt agttcatgag atactctctt tgtatgaaat caagtatatt
    29461 ttcataattt caacaatgaa agagaggctt atctctattt tgagacagcc tcttctttta
    29521 aatttatatt tctagaattt atgtttttta tttatccaac attaacatta gttattagaa
    29581 ataattttaa gaaaaatata ctttcatgtt aatatcagaa taaatgtgtt tttaaaggat
    29641 gatttgtttt gaattttcac gaatatctac ttctatgact ttttctattg tatctcctct
    29701 aaaacctaat aaattacttg tcaagtttgc agtggaacaa gaatgattag gtataattct
    29761 tattctatca ccaattttta tatcagtttc accatttact ttaatttttc caacttcttc
    29821 tgaaagtgaa tcaatagtaa gttctggatg tccacatacc ctaccataac caacaatact
    29881 actatttcca tgtgcacctt tatcaagtcc aaggcactta cttccacaat caattaaata
    29941 gtatccactg ctattttttg aggttacagt gcacacaaca gtaagagcac acatatcttc
    30001 agtagcacaa cctaaaccta tctgtatagc atcatagtat acatagtttc caggtcttac
    30061 agcagttata gttttagaag cagcttcaga ttcaactgtt ggagtactac cagaagcgac
    30121 aatttctata ttaaatccat tatcagttag agctttgtat gctttctcca tagaagaatc
    30181 ttcttgaaca caaacatctg gaacaccttc tggagaacta caaccataca cttgacctgg
    30241 atgcgaactt ataccaacaa tcttgatgtt ttctagctta gaaatttcag tagcaagttc
    30301 aaccactttt tctggttcaa ccccaaaacg gtgtaagcca caatctacaa taataagtag
    30361 cttgcactct atttttgatt tagaaaaagc ttcactataa gccttagcac attctatatt
    30421 atctgtagca cagattaaat ttatttttga tgccatagtc acaattctat ttatatttac
    30481 ttctcccatg taaggataag ccaacataat atcttcaaaa cctgctttta tcagagcttc
    30541 accttcatca agtgttccaa ctagaaaacc actagcacct gcattttttt gaagtctcgc
    30601 tatgtaagta cttttatgtg tcttaagcat aggccaaagt tgtttattat tatttgtaca
    30661 aatttgttga attttatcta tattcttttc taactggtct aaatctagca aaaaatttgg
    30721 agtagcgact tctgaaattt tcatgttatt taccaccttt caacaaaagt aaattaacta
    30781 taagtattat aattattata ttagtaatat cggctttata atattaatag cttataatta
    30841 tattatagaa ctagcgttaa cagagagcaa tatttatttg taataattag aattttcaat
    30901 aagttagtgt agttttaaat tatttatata atatattttt aattttatgc aaagtttatt
    30961 taaattagtt tgaggattta ttaatagggt attattgaat gagtaaaaaa gtgatgttta
    31021 catagaataa tcacactata aattaattta gaacctaaaa aattaattga gcaaattgga
    31081 aaagagaagg ataaaaaaga tatttggata gttggtggag gcgatatagt aaaattattt
    31141 atgaaagata acttaattga tgattattat atatatatat tgccaataat attggggaga
    31201 gggatttcac tatttaagtc tggtatagac aagactaatt tgaattttaa gaaagctagt
    31261 aatattagag aacttgtaaa attggaatac agtaaaaaac aaaaataaat tacatgccaa
    31321 tttgttacaa tgttatgaaa cgaagcattt aaaagacttt tggctatatg aattgacatt
    31381 acttgtcaaa tatgttaaca tataagcgac ttgtcggagg gtgtattaaa aagaatatgc
    31441 tggagaagag agtgcgttaa ctcttttctc ctttttttat aaaattaagc atttataaat
    31501 ttagtattat tacatgatta cactatctca aaaattaaga aaggagaaaa atatgaaatt
    31561 aattttaagt tatttaaaga attataagtt attaatagta ttaaacatac tggctatatt
    31621 tagttttgca ttagtcgagt tggggattcc aactataata gctaaaataa ttgacaatgg
    31681 tattgcaaat cagaatatag cttacataaa acaaatggga atagtgattg ttattatttc
    31741 tattataggg gttgtaggta gtatattgtt gggttattgt tctgctaagg tatcaacaag
    31801 tgtaaccaga gatataagaa atgacatatt tgagaaatca caagaatttt cacatactga
    31861 atacaataaa tttggaattt cttcaatgat tacaagaaca acgaatgatg catttcaaat
    31921 tcaacaattt gttaatatac tactaaggac tgccttatta actccagtta tgttcattat
    31981 aagtataata atgacaatta gaaccagtgt ggaactttct atagtattgg ctatatcagt
    32041 accttttata attattggag tagcaataat agcaaaagta tctcaggcaa tatcttcaaa
    32101 acaacaaaaa ggactagata aattaaacct tatatcgaga gaaaatttaa ctggaataag
    32161 agtaattaga gcttttggaa atgatgatta tgaaacagag cgatttgaaa aaacaaatac
    32221 atattatgct aatgtttcta agaaactatt taagcttatg tcaattactc aaccagcatt
    32281 ctttttactg ttaaatatag ctgttttggc tgtattttgg atttcaagtg agaagataaa
    32341 tattggagag cttcaagttg gacagttggt tgcatttttg gaatatcttt tccatgccat
    32401 gttttcaatt atgctttttt caatggtatt tattatgtat ccaagagcag aggtatctgc
    32461 aaatagaata aaagaactat taaatgaaga accattgata aaaaatcctg aaaatggaat
    32521 taaggatact gaaaataagg gtatcataga atttgataat gtaactttta cctatccaga
    32581 tggagaagct tctgtactta aggatatttc atttactgca aaaacaggtg aaacagtcgc
    32641 ttttatagga agtactggta gtgggaaaag tactctaatt aacttgatac ctagatttta
    32701 tgatgtaaca gaaggtagca ttaagataaa tggagtagat ataagagaat atgatttaaa
    32761 agctttaaga aaaaagatag gattcatacc tcaaaaatca ctgtttttta ctggtagcat
    32821 agcaaataat attagatttg ggaaacataa ggcaggagag tcagaattag aatattccgc
    32881 aaaagttgca caagcatatg agtttatatc aaaaaaacct agaaagtttg atgaattgat
    32941 tagtgaaggt ggagcaaatg tatcaggagg tcaaaaacaa agactttcta ttgcaagggc
    33001 tattataaga agacctgaaa tatacatttt tgatgacagt ttttctgcac ttgactttaa
    33061 aactgatgca atacttcgtg ctaaattgaa gaaggaaaca aaagatgcaa ttgtattgat
    33121 tgttgcccag agaattagtt ctattattga tgctgataag attatagtac tcaatgaagg
    33181 acaagttgta ggaatgggaa ctcataaaga attattaaaa aactgtgaaa tatactatga
    33241 aattgcaaca tctcagttaa aaaaggagga attagaataa tgaaaaagtc taaaggtttt
    33301 aagaaaacaa ttggtagact tcttccattt gtaaagaaat ataaattttc ctttattata
    33361 gctattatat gtataatttc agcagctact atgaatgcac ttgcacctaa aactgaagga
    33421 ttgataataa cacaattgac taaagatgta attagtatcg caaaaggagt accaggggct
    33481 tccgtaaatt ttgattatgt aacaaaaata ttggtgattt tagcatgtat atattttgcc
    33541 aatgcaattt ttacgtatac ttcaagtttt ctacttacga atgctattca aaacacaatg
    33601 agagatttaa gaaatgaagt cgaaaataaa ataagaagat tgcctattag ttattttgat
    33661 agtaatagtt ttggagatgt attaagtcgt atatcaaatg atgtagatac aatatcaaat
    33721 gcattgcaac agagttttat gcaaattgta aactcaatct tagtcataat tttggcactt
    33781 tcaatgatgt ttacaattaa tatatatatg gctcttatag ctctttttat aattccaatt
    33841 agttattttg tatctaaatt tgtagtaaaa aaatctcaaa gtagattttc attgcaacaa
    33901 aatgctcttg gaaaattaaa tggaaaagta caagaaatgt atactggatt taatgaaata
    33961 aaactatatg gtaaagaaga agattctata aaagaattta aaaaagtaaa tcaagaactt
    34021 tgtgaaaatg gatttaaggc acaatttata tcaagtatga tgaatcctat ggtttcatta
    34081 gtaacttact ttggaattgc agctgtggca gttgtcggtt ctatatatgc agtaagtgga
    34141 ggaataacag taggaaattt acaagcattt gtgcgttata tatggcagat aaatcagcca
    34201 ctttcacaaa tgactcagtt atctacagta atacaatctt cttttgcagc tatagaacgt
    34261 gtatttgaaa ttttagacga agaagaggaa atacctgatg ttgaaaatcc agttaagata
    34321 gaaaatgtaa aaggaaatgt tacatttgag catgttaatt ttggatatgg agaaaattca
    34381 actttaatag aagatttaaa tgcagaagta aaaagtggtc agatggtagc tattgttgga
    34441 cctactggag caggtaaaac aacattaata aacttattga tgaggtttta tgatgtaaag
    34501 aaaggtgcta ttaaaattga tggagtagat ataagagata tgaaacgtaa agatttgcgt
    34561 tcaatgtttg gtatggtgct tcaagataca tggttattta atggaaccat ttttgaaaat
    34621 atagaatatg gtagatttgg ggctactaaa gaagaaatta tacaagcagc aaaagtagca
    34681 aatgttcatc actttataac cactcttcca gatggataca atatgttttt aaatgaagaa
    34741 gcatctaata tatctctagg ggaaaaacag cttttaacca tagctagagc ttttatatca
    34801 gacccttcaa tattgatact tgatgaagct acgagttctg ttgatactag gctggaactt
    34861 atgcttcaaa aagcaatgag aaatcttatg aatggtagaa ctagttttgt tatagcacat
    34921 agactttcta caattcgcaa tgctgacttg attttagtta tgaataatgg aagtattata
    34981 gagcagggga atcatgatga attaatggaa aagggtggat tttatgagaa gctttataat
    35041 agccaatttg cagacaaaga atcagaatag ataacataaa cttttgtata aaattttgta
    35101 tcaaattcaa atattaatca tataattaaa aagagtatca gtaagttgtt tttttataga
    35161 tttactgata ctctttgatt ttaagaccaa aggtacttat gattggtact tataattcac
    35221 aactagtctt gttacatctg ataaccagaa ttacagtact tttctttttt acctttttgt
    35281 tctctaacat ataacaattc gcttaactta tcaatgtaat aaccatcatc acttatgcga
    35341 attaaactag tcagataata tccatctttg cttctaggaa tctttttatt tattgctaaa
    35401 tcaatagctg tctttgctgc ttcaaaatgc tttaaatgtg tatgaccttc ttcaaaactc
    35461 tttctagtat tataaactac ataacctttt ttaacttgaa aaactataaa ttctttcttt
    35521 tcatatattt tattaaacat tcaatcagcc cttctcaaga tagttttata gcataacatt
    35581 agaagcttct aaaaaatttt acaaagaaca taaatatttt ataaattata aatctaaaac
    35641 tataatttat aaagataact ttctgattat ttatatgata attcatatag attaaaagta
    35701 aattatcttt aggttaaaca aaagtaaaat aaaagactag ttataatatt tatatgaaaa
    35761 agtacaaaat atagtatatg aatatagaaa atttaaatta tttatttaca gtttttattt
    35821 ccataagtat atttaccttc agataccttg tcatcatgga aatatattct ttcacaactt
    35881 ttatctcccc atagaatgtt ttttgttatt ttatgggacg tatcccctgt aaatacttca
    35941 gctacagtag tatctgtaac atcacagtaa agagaagcga attttttaaa ccaaggattt
    36001 tcctcaaatc ttaaaagcca ggacgctcca taggggcaat gtaactcttc aaattcagga
    36061 acccatccta gaaatggaac atcagttgtg ctaataatat tgtctgcaat taattcatct
    36121 ccattttcat gagctttctc tctcatagca atagctcttt cttcagacct ttcaaataaa
    36181 acttttctta atatttcgct agttttatct tcaccaaact cttcaaataa cactttggaa
    36241 aaataaaaat ataaatcacc aaaatgtttg catgccatac gaacttcttc aatagcataa
    36301 tctttgtcaa tagtttcatt agttacaaca tcttcgttca aaaaaatcac tccttagaat
    36361 aagtattagt tacaatataa ttatagaata ttttttataa attaggaaat taatttgaga
    36421 tagatatatt tttaataaat gaaggtataa tgctaaaata acttattgtt acaaaaatct
    36481 tctaaattaa tgtatttagg agtttccata tgaatgagag tagttctgta aatatcttca
    36541 atacatccat ttgcaatatt attaaaaata tctgtgtgct cttttaatgt tgtttcaagc
    36601 cttccttcat gtgacaatga atcgagagct aattttttta ttctgtacat ataattgtta
    36661 aacattttgt caaattcagt attttgagca tatgaaacta tagttgtgtg aaataatgta
    36721 tcgtattctg caaatgagtt taaattttta tcacctaata aaatatcttt ttgtttatct
    36781 aaaagatgtt ttaatttact tatagtttct actgctctag cttctttgta ttgacttgta
    36841 attaaaaaag tacaaaaccc ttctattgca gagcgtattt ggaatatctc tacaatttca
    36901 tttgctgtaa tttgatggat tctaaatcct ttgcttggga ttatatctat aaatccatct
    36961 tgactaagtc tttgaagagc atctcttata ggtgttctag agatacctat ttcactagca
    37021 agttttgttt cagaatatat ttcattttct atcatttctc cagatagtat caattctttt
    37081 aagtagtcat atgcttgttc ttgtaatctt ttaaatgtag ccatacttaa taataccccc
    37141 ctaaacaata taaaaataca aaaacttata taattttaag catacaacat agtgaaaata
    37201 aggtcaatct tttgcaattt aaattgcaga taagattaaa aaatataaaa aattattgaa
    37261 gtgtgaagca tgattaacat taaaggcaga ttaattaaaa ctaattgaaa ttagttaaaa
    37321 tacaaaactg taaaagtagt atattatatt tgaaaacaat agtatgtatt aaaacttata
    37381 taggatgact aaatataata aatgacttta aaaattacta tttattgtta aaataaatac
    37441 ttttatattt tatattgacc ggtatactgg tatgtagtat actctaaaac ataaaaaacg
    37501 ttttcaaaaa tgtgaagata tggagggtta taaaatgaaa ttgggattta ttggattagg
    37561 aataatggga aagccaatgg caaaaaattt attaaaagat ggatgtaatc ttttggtgta
    37621 tgacattaat aaatctgctg tggatgaact tatatcatgt ggagcaaaat acgcaagtgt
    37681 tttagaaatg ggtcaagaat gtgatattgt atttacaatt cttccaaatg gaactattgt
    37741 gcaggatata ttatttggga tggatggatt ggcaaaaact ttaaaagaag gaagtatagt
    37801 agtcgatatg agttcagtta ctcctacaga atcaatattg tgtgcaaata aattaaaaga
    37861 tatgggctta gaatttatag actcaccagt aagtggaggg gagccaaaag cgattgatgg
    37921 tacacttgct tttatggctg gtggtaagga agaaatttat aagaaagtag aaccattttt
    37981 taatataatg ggaagctcat ctattttaat tggagataat ggtagtggaa gtgttacaaa
    38041 acttacaaac caagtaattg ttaatttgac gatagcagca gtttctgagg catttgtact
    38101 tgcagcaaaa gcaggtgcag acccagaaaa agtatataag gcaataagag gaggcctagc
    38161 tggtagtaca atattggatg cgaagatacc aatgattatg aatcgtgatt ttaaaccagg
    38221 tggaaaaata tctattaatt tgaaagatat taagaatgta atgcaaacag cacacaattt
    38281 agatgtaccg ctacctatga caagtcaatt attagaaatt atgcagacat taaaagtaca
    38341 tggacatttg gaagatgacc atagtggaat agcacagtat tttgaaaagt tggcaggtgt
    38401 tgaaataaaa aaacacaata attaatattt aaatatatca atataattaa atacatatta
    38461 ttaggattag attatataaa tacagcgagg ttaagttatc atagtaaaag aaaaataaaa
    38521 ttgataaata ataaagtaga atgataaagg ggtaaagatt atgattacag gatatggact
    38581 tttgatagca tttgttatat ctataggaat tttacttgta tcgattatta aatttaaagt
    38641 aaatccgttt ttggcattac tgataacatc tataattaca ggctttatgg ttagaatgcc
    38701 tataaatgaa atatcaacca caatatcgac tggatttgga aatacattag gtagtatagg
    38761 tattgtaatt ggacttggaa taatatttgg aaatattctt tcagaatcaa gagcaacaga
    38821 atctattgca aaggggttgt tagctaagac tggagaaaaa aacagtgctt tagcagtaac
    38881 tacagcaggt tttttaattt caattccagt ttttatggat gcagcttttg ttataatgat
    38941 gcctataatt aagtatgttt cgagagtaac taagaaatcc ctaatggttt ttgtatgtgc
    39001 attaggagtt gggactatag taggtcatgc acttgtaata cctacaccag gacctttagc
    39061 agttgcagca aatgtaaatg caaatgtagg tagttttata ctttattcta taattgttgc
    39121 ttttccagca gctcttatag gtggatggat ttatggaaaa cgttttgaaa aatatccagc
    39181 ttatgctatt gatgagaatg atagagaaaa aaatttagag cagggaaaag atagcataaa
    39241 aattgaagaa gatgattctt ctaaagtacc aggttttgga atttctatgt tttctttatt
    39301 gttcccaata cttcttatac ttatatcaaa tgtatttagt atgttcttag aaaaaggttc
    39361 tacaatgagt ggagtacttg catttatagg agataaaaac atagcaatac ttcttggaat
    39421 attggtggca ataggatttt taaagaaata cataaataaa cctatgggag atgtagttat
    39481 tgaagctgct gattcagcag ggttaatatt attgataaca ggttcaggtg gtgcgtttgg
    39541 cagtgttata aatgcaagtg gtataggtaa cttcttagtt gatactatgt ctggtcttag
    39601 tatatcagtt gtagtgcttg gattcttatt aagtgccttg cttagaattt ctcaaggttc
    39661 tgctactgta gccttagtaa caacatcatc aattttagga cctacaattt tggcaactgg
    39721 aatgtcacca gttttagtag ggcttgctat atgtgctgga ggagttggtt tctcccttcc
    39781 aaatgattct ggattctggg tactttcaag atttagtgga ttatcagtta aagatacttt
    39841 aaactcttgg acaattggag gaaccattgc tggagttgta gcgtttataa tggttttatt
    39901 gcttagtgtt ataaatggaa ttataccact tccaggtcta taaataacaa gctattgttt
    39961 atatcatata aattatattt agactataca aattacataa aggggcgttt taaatgagag
    40021 aagtaaaacc aattagcata gatatactta atacttttaa acaagtagat gaggacagat
    40081 taaatgaact tcttgcagat gagcttaagc atttagatag aaaaattgtt gtattagatg
    40141 atgacccaac aggtgtacaa acagttcatg atatttctgt ttatactgat tgggataagg
    40201 atagtatgga acaaggtttt aatgagaaaa atagtatgtt ttttatactt actaattcaa
    40261 ggggatttac tgttgctcaa actacaaaag cacataaaga aatttcaaag aatattgtgg
    40321 atgtatcaaa gaaagttaat aaggatttta taatcataag tcgtagtgat tctactatga
    40381 gaggacatta tcctcttgaa actaatttat taaaaagcga agtagagaga ttatcgggga
    40441 agttatttca gggtgaaata ataatgccat tttttaaaga aggtggtagg tttactatag
    40501 ataatgtaca ttatgttaaa gaaggagaaa tacttgtacc agcaggaatg actgaatttg
    40561 caaaagataa atcttttgga tataaatcat ctgatatagg tgagtggtgt gaagaaaaga
    40621 caaaaggaaa gtacaaatct agtgatatga tatatatttc gtcaaaagaa cttagagagc
    40681 taaatattga agctataaca gaaaaactta aaaaagctga aggattcaat aaaattattg
    40741 taaatgcaac cgattatgta gatgtaaagg tatttacaat tgcgtttata cgagcagtaa
    40801 atagtggtaa ggaatttatg tttagaagcg ctgctgccat aacaaaagta cttggcggag
    40861 tgagtgacaa ggaactactt actaaggatg aattagtatc aaaaggtaat actaatggag
    40921 gaattatact tgttggttca catgtgaata agactaccca acagttagaa gaacttaaaa
    40981 attgtaaata tccaatagaa tttatagaat ttaatcaaca tttagttctt caagaaaatg
    41041 gtctaaaaaa tgaggtaaaa agagttataa aagttgtaga ggaaaaaata agcagtggta
    41101 aaactgttgc tgtttatact agacgagagc gttttgactt ggatacgaat gataaagata
    41161 aacagcttat gatttctgta gaaatatcag atgcagttac cagtataatt ggtatgctta
    41221 atgtaagacc aaattttatt atagctaagg gtggaattac ttctagtgat gttggtacta
    41281 aagcactaag agtaaaaaaa gctacagtaa tgggacagat aaaacctggt ataccagtat
    41341 ggatgacagg caaagaaagc aaatttccta atatgccata tataattttc cctggaaatg
    41401 tgggagagat tagtacactt agagaatcag ttgagatatt gatggggtag tatattagtg
    41461 tattgaagtt taaacgctta aatttactgt gttaaaagta aaataaacta aaattataaa
    41521 ttaagattaa aaataatagt atattaatta gggtttagag tattttacaa aaata
//
LOCUS       DAEORM030000033        41210 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.033, whole genome shotgun sequence.
ACCESSION   DAEORM030000033 DAEORM030000000
VERSION     DAEORM030000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 41210)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41210)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 41210)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41210
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.033"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            complement(13..867)
                     /locus_tag="KRH23_002258"
     CDS             complement(13..867)
                     /locus_tag="KRH23_002258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative ABC transporter permease"
                     /protein_id="HHS5225536.1"
                     /translation="MSTFYIQFLYFVIYSFIGWCCETTYCSVLQKQFVNRGFLNGPFC
                     PIYGFGALAIVATLTPFVHNIPLLFLFSIIITSIMEYCTSFILEKIFNMTWWDYSKHK
                     FNIHGRVCLENSLMFGVLSLIVMLIVHPIVVDFINSISKNVLFIFAISIEIYFVLDLV
                     ITVHTILQLNGKLKQINLIIKELKDKKEYYKLITQETIENKLESLVENRLDTLEDRFE
                     ILKEKENYRYAKNRIDELKNKLNTLLSNHKLLHRRIIKAFPNISSNKHTDILNKIKEN
                     IKSIKKDK"
     gene            complement(1135..1458)
                     /locus_tag="KRH23_002259"
     CDS             complement(1135..1458)
                     /locus_tag="KRH23_002259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1540 domain-containing protein"
                     /protein_id="HHS5225537.1"
                     /translation="MERINCNVINCSHNNSHICYADKIFINGEKAHNDRHTCCSSFLD
                     ESIYSNLSSNVNNRNCEELVCTVKNCKYNKDGSLCTLDNILVAPETDRVNLYIETCCS
                     SFECK"
     gene            1661..2290
                     /locus_tag="KRH23_002260"
     CDS             1661..2290
                     /locus_tag="KRH23_002260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5225538.1"
                     /translation="MFEKKKKELFPWKISALILVGVFVLSSGVYIGTRLKHNGVQTGE
                     VVSTSANMNEKSKEAFGLNKNCEVWLQSEGENETNYKRTLTMAGIVPESLLDKTKSEI
                     VSYFKKEYPTKKIKSMDKNEIILVESKYSDNKDVQAMDVTIKGKYTIENDNGNIALYK
                     YDDSGSKTLVEKTKIRVDSLPKTVQDEIKKGVVMDTEEEAYSRLEDFAS"
     gene            2602..3111
                     /gene="ruvC"
                     /locus_tag="KRH23_002261"
     CDS             2602..3111
                     /gene="ruvC"
                     /locus_tag="KRH23_002261"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008821 - crossover junction DNA
                     endonuclease activity [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="crossover junction endodeoxyribonuclease RuvC"
                     /protein_id="HHS5225539.1"
                     /translation="MIILGIDPGIAIVGYGIIEYKNSKFKVIDYGAVTTPAHMNISRR
                     LELVYKGIDTIVKNYNIDEVGMEELFFNKNVKTAITVAQARGVTMLACAHNGKPVYEY
                     TPLQVKQGVVGYGRADKAQVQQMVTSFLSLKKVPKPDDVADALAVAICHAHSNKLEKT
                     LKNIGGKYV"
     gene            3104..3706
                     /gene="ruvA"
                     /locus_tag="KRH23_002262"
     CDS             3104..3706
                     /gene="ruvA"
                     /locus_tag="KRH23_002262"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009379 - Holliday junction helicase
                     complex [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0009378 - four-way junction helicase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HHS5225540.1"
                     /translation="MYSYIKGTVEEIYIDSIVVENNGIGYKINVSSNTIMNLQVGEAT
                     KIYTKLIVREDDMSLCGFVSREELKMFELLTSVSKIGPKVALSILSFASPAQLGAYIL
                     SEDIGKLSKAPGVGKKTAERIVLELKDKVDKNNIEFEPTLLSQKPTLISQDESVDALV
                     ALGYTLSESKEAVQKCKKDGMNTEAIIKKALTYIMSKSLK"
     gene            3813..4832
                     /gene="ruvB"
                     /locus_tag="KRH23_002263"
     CDS             3813..4832
                     /gene="ruvB"
                     /locus_tag="KRH23_002263"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0009378 - four-way junction helicase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HHS5225541.1"
                     /translation="MQGFEDENRIITSTMKMEDIDIENSLRPKTLEDYLGQEKSKEQL
                     SIFIEAAKSRNEQLDHVLLYGPPGLGKTTLASIIANEMGVNLRITSGPAIERAGDLAA
                     ILTNLNENDVLFIDEIHRINRSVEEVLYPAMEDFCLDIIIGKGPSARSIRLDLPKFTL
                     IGATTRAGMLTNPLRDRFGVICKLDYYTVDELSKIVLRSSSILDAEIQSNGALELAKR
                     SRGTPRIANRLLKRVRDFAQVRADGKITDKVAKDALELLGVDSLGLDFVDEKLLMTII
                     EKFRGGPVGLDTLAASIGEDRNTIEDVYEPYLLQLGFINRGPRGRVAMPLAYEHLKIP
                     YPNEK"
     gene            4921..5049
                     /locus_tag="KRH23_002264"
     CDS             4921..5049
                     /locus_tag="KRH23_002264"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5225542.1"
                     /translation="MVIISVDTVDKHDKNCVYCIYILWIRHVYRGKISIYCGYGVC"
     gene            5150..6175
                     /gene="queA"
                     /locus_tag="KRH23_002265"
     CDS             5150..6175
                     /gene="queA"
                     /locus_tag="KRH23_002265"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HHS5225543.1"
                     /translation="MKTSDFKFDLPQELIAQVPIEDRASSRLMVLDKETGNIEHKVFR
                     DIIEYLNPGDCLVLNNTRVIPARLIGEKIETGGKIEFLLLKRTEEDTWQALVKPGKRA
                     KVGTKFSFGNGKLIGEVVDLSDEGSRIIKFHYDGIFEEILDELGNMPLPPYITARLDE
                     KERYQTVYSKHNGSAAAPTAGLHFTEELLNKIKEKGVDIAFVTLHVGLGTFRPVKVED
                     VLNHKMHSEYYMVSQEAADKINRAKENGKNVICVGTTSCRTIESACNEDGKMKETSGW
                     TEIFIYPGYKFKVLDKLITNFHLPESTLIMLVSAICGKDNVLNAYNEAVKERYRFFSF
                     GDAMIIK"
     gene            6187..6672
                     /locus_tag="KRH23_002266"
     CDS             6187..6672
                     /locus_tag="KRH23_002266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate-starvation-inducible PsiE family
                     protein"
                     /protein_id="HHS5225544.1"
                     /translation="MHSLQKQKKNNPILKIAFIFERVLAVVVLIAVFLGTIDVLRLMW
                     GAYIVDFQNPVQYSQLNDFLAQILLLVIGVELVVMLSLHIPGAFIEALLYAIARKMLL
                     LPKNEGMIDVLIGVIAIAGLFAIKKFLVTKDKSALNIMSIHDEEAIKEQQNKEDEDKS
                     I"
     gene            6751..7872
                     /gene="tgt"
                     /locus_tag="KRH23_002267"
     CDS             6751..7872
                     /gene="tgt"
                     /locus_tag="KRH23_002267"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008479 - tRNA-guanosine(34) queuine
                     transglycosylase activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HHS5225545.1"
                     /translation="MYAVRYELIKTCKQSGARLGRLHTPHGIIETPIFMPVGTQATVK
                     SMTPEELKEIGSQIILSNTYHLYMRPGHELIKRAGGLHKFMNWDKPILTDSGGFQVFS
                     LGPLRKIKEEGVEFRSHLDGSKHFLTPEKAMEIQNALGSDIMMAFDECAPYPSDREYV
                     KNSLERTTRWLKRCKDAHNNTDKQALFGIIQGGMYKDLREQSAKEITNIDLPGYAIGG
                     LSVGEPKPLMYDVLEHTTPLMPKDKPRYLMGVGSPDDLVEGVIRGVDMFDCVLPTRIA
                     RNGTAMTSQGKVVVRNATYAEDFTPLDPECDCYACKNYSRAYIRHLIKANEILGARLI
                     TTHNLHFLLNLMKQIRQAIMEDRLLDFRNEFFAKYGYEI"
     gene            8006..8299
                     /gene="yajC"
                     /locus_tag="KRH23_002268"
     CDS             8006..8299
                     /gene="yajC"
                     /locus_tag="KRH23_002268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HHS5225546.1"
                     /translation="MPQQQIIMSIGLWVVVIAIFYFLMIRPQKKKDKQLKEMRSSLSV
                     GDKVITIGGIVANVAKVEDDVVILELGPNRTKVPFEKWAIGTVKSKKEEIEED"
     gene            8357..8719
                     /locus_tag="KRH23_002269"
     CDS             8357..8719
                     /locus_tag="KRH23_002269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04086 family membrane protein"
                     /protein_id="HHS5225547.1"
                     /translation="MGKSNYIFKGLGYAYIITLAVLLVYNLFLTFTDIGGDNITMVSS
                     FITTISAAIGGFYTSKHMKEKGLMYGLLVGLLYIVCIFLTVFLAQEKFVFEVGMIYKL
                     LLISAAGGIGGVLGVNFK"
     gene            8785..8928
                     /gene="scfA"
                     /locus_tag="KRH23_002270"
     CDS             8785..8928
                     /gene="scfA"
                     /locus_tag="KRH23_002270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="six-cysteine ranthipeptide SCIFF"
                     /protein_id="HHS5225548.1"
                     /translation="MENKHVKTLSQATLKQSAAKGGCGECQTSCQSACKTSCTVANQE
                     CER"
     gene            9554..11449
                     /locus_tag="KRH23_002271"
     CDS             9554..11449
                     /locus_tag="KRH23_002271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp8"
                     /protein_id="HHS5225549.1"
                     /translation="MLSNKKRSMAIVMAGATVMSAAAPIFADNTVTENVDKNYTVSAK
                     DSAKLIEEVRKALEVKFEDTKAGANVNDRVYDIKVDNVNLTNATQLQNKINSLTEGQS
                     LKVTIQDKGHQVLGGKVVDYKIENYKTAQEIVDAVNAYNATLAEDSDNKLTATIKSTN
                     TVEVKRAKDSANVITLNVGDQHLDFSKVITSEEGTFEGYEKSYSDIDSKELHTITVKN
                     ADLQDISAEELFDGIRLTTLGREIVNKVKNGYALTFENEAILTQEQEDSDDKDKPEKS
                     SFDIVLSKANEKPETISVSSKNHKLVRDLHKVLTDVKDGKELKVEVLSGDSRFTTAVE
                     VSKERFKDGEAEAIILVGEDAIVDGLASAPLASQKNAPILLSKKDSLPSEIEAEILRV
                     LGSNLSSKKIYIVGGESKVSKETEEKLSKLGVSKVERVSGEDRFETSLEIAKQLKDTF
                     KTAFVVGGNGEADAMSISARAAQFGAPIIVTGNELDANAEKLLKGKELEIVGGENSVS
                     KEVEDKLVDIDLNNKVERLAGENRKDTNAKVINKYYAGATKAYVAKDGYVGGNGQLVD
                     ALTAAPLAASSKAPIVLTTEELSKSQEEVVELRLKNATKLVQIGEGIAKNAIEKIAEK
                     INLFTKN"
     gene            11911..13314
                     /locus_tag="KRH23_002272"
     CDS             11911..13314
                     /locus_tag="KRH23_002272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp9"
                     /protein_id="HHS5225550.1"
                     /translation="MKNSKKILAIGLTLFLVMVNTPMVNALTSVEQIKGNDRYETAAK
                     IADKQNYNTAILINSDNSLADGLSASGLAGALNAPILMTKQNQIPNTTMERLNKAKTV
                     YIIGSESTISKNVENQLLSKKKVVQRIFGENRFDTSIKIAEKIKEIKPIDKVIIANGF
                     TGEADAISASPVAARDGVPIILTDGNSVGFDTTGLKSYALGSSEIISDELVKSTNSIR
                     LGGTDRFETNKIVIQEFYKNSKEFYLSKGLQLTDALAASTIAKNAPVVLVENGSNKSI
                     LSGADKLTVLGGINQNVIKQCINQASPNQQGLYYNPNDRAFKERIKGKVYALTKQYRK
                     ENGVRALSVASRLEGLANDWSNLMANKKTLSHTINGKNSYSTFLKYLDWSEIKPGYIA
                     VQGENIIKYKIPDKPVYTNRDADDIGNFIFNEWKTNPEEGTNMLHKGYEIMGFGIAIT
                     GDKNLYATHEFYGRYKE"
     regulatory      13486..13571
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            13695..19658
                     /locus_tag="KRH23_002273"
     CDS             13695..19658
                     /locus_tag="KRH23_002273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M60 family metallopeptidase"
                     /protein_id="HHS5225551.1"
                     /translation="MKKAISCVLAVSMCSAPLNVFAEPILEGKLRAVEKSVTEKLRGS
                     LEVDLNFSLPIKNSESESMTNMQLRLKDDSNNSGIIKLGEKDSGTVNVGTDNIEYTIK
                     KLSASRSEIKNKDENVSYYSIVFNNLPVGKYNVEVSGAGFKNKEIKDIDISSYSQRVL
                     LSNRASVDNKNEPLNYELFLMGDVNGDGKVDKSDYNKVLENIDSNKREFDLNRDGKVD
                     IVDLDYVQKNLGQSEDAKSLESIVSTNPIVDTSKVELKGNSDVDINGNVENLFSGENN
                     GVTISSKNDEISEEKPAVMDIALSEALNMEVINIKAPEGTAPAKGIVEVTDKDGNVQQ
                     IPYENKEYMKNLKDDEQQEEVNNEQEEVNQEEVNNKDENINQTDNNSNNKDENNDKQQ
                     ENSDKQEVNSNTNQDKNNDKENSSMDKPNSDEDTPKEEGNISKDDNSTTSTYSRSALE
                     TYADVQNSDIVINLGKQVAVKKITIKITATTANDRNLAEISKVEFLNNVYKEIPKPEM
                     NIPKINKISTSTAVGNEKVSFYWNNEVNVSAYELILDKIDSKGKVLSTKKLQTSKNTI
                     EVRDIEAYGLYRVSIQSLNGDWSSGYKDATPENLDGVPENVDSNYKPIQFSPDSILEF
                     QVVPDTKPEPPEGINVKGKFKSLDVSWKTHKQAKDFDLYYKEKGSNGSWIKYNDKLIR
                     GTSSKIEGLKDNTTYEVRMTATNHLGTSVMSKTYIGTTESMDAPTTPNYRLINTPKEN
                     GGFGIPTNHIVDVTYPAGYDKSEYSDKNPFDKFNVVDGDFTTHWTFPTYNAAEGTNRG
                     PIITFDKSYTMDTFMATPRFDVSDKTINDFEVRYWDENGQLHNLGDVPFETKTDPVNN
                     NKYVMVRLKEPITATKIQVSVCSSYSYKSNISELKFYEYDSIEDDVRNLFMDDLQVEL
                     KEDVTQEKITKLKDRLNTPDKASGEYHPYKTVIERELKLAQDLYNDRATLTDVTTVNQ
                     EINKLGKYKDKNGQYTVNSNNLGMQNDWQALGVAARAGDEITVYVGSKSGKTPKLIYT
                     QYYGESGAYKSGEINLNTGKNVIQLSKLHSLDIECGGSLYIRYAEDTPSGGDIKVRVA
                     GATKIPHLNLNGTINDKSPAGVSESKKKIKAYIEELAKYKDAVKGEPYYPGTNVGNSY
                     GYSEKTGVLNTTDIESDKVTLNVPATAVYQGISKGNADLNTQVDRLYNSMLAWEQIMD
                     LVYSERGVFKTQDLDGNGTVDDNEFNLTKNDMAPKSRMNIKYQRMFIGAFMYASGLHV
                     GVEYGSVPGLMNGVPFQIDDSGKATGGNLFGWGIGHEIGHVTDIGKMTYSETSNNVLA
                     LLAQTFDDKTHSRLEGSTMDKIYEHVTSNSLGIPSNVFERLGMLWQLHLAYDDDFTGS
                     MLKNNSDADLSNDTFYAKISRKYRALSSSDPINSLPKDQMLVAMASSVVEKDLRDYFK
                     AWGVEITPELNSIMDSKNYEKESRKIQYVNDEARRKILNENIASMAKDTKVSASFSDG
                     IQSGSLVKSNKISIDLDVDKDKDKILGYEIIRSDGNYLDGENGTQVKYRTVGFVDAKG
                     NSKTKFTDNISPLNNRAFTYKVVAYDYHLNPTEEFEVGTVKLSDEGKINKSAWSFITN
                     TVSDGDVRTENDSHGPLQNPEIDNIKDNDASTTYKGKIISKAEWNKDPQKDPDINVEE
                     NPYIIVDMKETLPIVGLKYTKPEAEARKFSLKGLFNFRKNTSTTYNPLTNYKIQVSND
                     KKNWEDVSQGTFEYGQDLVGGGKDQDNEARVTFNKDGKLWTYQARYVKLISNNKSNIE
                     VAELDIIGPPGDNIEIGTMNNADQTRTNGIGKLAEDYVYQSDDSRTSEDETGKIPAGS
                     IVITGEYSGNPAFNLPLLIDKNNKTISGEALLFAEVPEKGELGEISKGTWVYYMPKEN
                     FDSLSDKVKAELYRYNDLQEDTPVGQRFVSDTMYVPVGAKNYDELKTISLTDSNSKAR
                     KATRNAIDISNKKVITVSNKVKGNIVRDK"
     gene            19868..21748
                     /locus_tag="KRH23_002274"
     CDS             19868..21748
                     /locus_tag="KRH23_002274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp10"
                     /protein_id="HHS5225552.1"
                     /translation="MSKRKSFIRTIAVSTMSVAVTGSATCAYAAPVLQGTKTYEKVNT
                     IDISVDSVENIVYSFQASIKVQGEVEVVDNEQKEKITWSDNIKSQIKSGNANATCRAE
                     YNKSSNTTTLDIYVTSNEDLLDGNRLNIGRISVKKSGSNSNADYKVLGKGTNDKPALK
                     IVTYNNKTVDYENISSDEGLIFTLINESEVKPIGGTGSSKNDPEKYKVEKSEALEYLL
                     NNIRINYSIVSKETQESGSNVILKLGLAQKTTKGRKATINKYVEVTLPKSLEYIVENE
                     LSKPDELPPDNGNGGNNGGGSNSGGSSSGGSSGGGNSSDSTSNVTVKKLKGADRFETA
                     IKISQSGWTKSDTVVIVNGEDKSMVDGLTATPLASVKNSPILLSSNEKLPQKTVEELK
                     RLNPSKVIVIGGNNSMPNLVVEAIKAVNSKISVQRIGGDTRYQTSINIAKEIDKTNNV
                     SKLYIGAGNGEADSLSIASLAGKEKTPIVLTQKDGVDSEAEQFIKSNKVSNIYFIGGI
                     EKISNKAIEQVGKIANKDISKNRVAGQTRQETNAKVIDKFYSQSKLDGVVVANQDKLI
                     DALAVGPLAAKNNSPVILATNTLDKSQESSLKGKNSSKLFEVGGGIASSVIDKIKSLI
                     EK"
     gene            22115..23716
                     /locus_tag="KRH23_002275"
     CDS             22115..23716
                     /locus_tag="KRH23_002275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp11"
                     /protein_id="HHS5225553.1"
                     /translation="MKMNKKILSLGLAVSLILVNFKSVNASSVVEKIYGKDRYETAAK
                     IADKQTYETVILVNTEKSLADGLSASGLSGTTKAPILFTQQNKIPADTNRCLKNIKKA
                     YIIGTEDTISKSVEKELDSKNIEVKRIGGEDRLKTSYLIAKEIATIKKVDKVLLTNAY
                     SGEADAMSVSSVATRDGAPIILTDGKSVPFDVKNIQSYCIGSEEIMSNPLVKNTNSVR
                     IEGTDRFETNKNVIDYFFNSADGFYVSDGYQLVDAIAAAPLTKNSPMVLVNDGSDKTV
                     LEGAKNITSVGEIDEKVIQQCISASKSNGQPPTITVGSTEIYKGEKFDTGKLNIVAKD
                     NTGKVLPIEVDGFIDTNRVGTYILTLKATDEWGESTEKRVEIKVLDDKSHDYNSPEFK
                     KMVSTEMYNLINSYRKEKGKEPLVVSSRLEGMANSWSKYMMDKKVFAHYIDGKNAPQV
                     FSEFGMRSEENIAYIYIDSKNVQTTQDAKDLAKAIFEVWKKSPEYNANMLSDEFYSTG
                     FGLYILSDGQVHATQEFLNGNEGSL"
     gene            23935..25533
                     /locus_tag="KRH23_002276"
     CDS             23935..25533
                     /locus_tag="KRH23_002276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HHS5225554.1"
                     /translation="MKVNKRVLSIGLTISLIMAGAPNINALSSIEKIQGKDRYETSAL
                     IADKQIYDTVILVNTDNSIVDGLSASGLSGVVKAPIMLVQRDKIPTDVEKRLKDVKNA
                     YVIGTEDTIGKSVENQLKNKGIEVKRIGGEDRIKTSYLIAKEISAIKPVNDGDKVFLV
                     NGYTGEADAMSVSSVAARDGVPVILTDGKSIPFKVDGVQCYSLGSEEIMSNELVSKTN
                     SVRIAGKDRFETNKKVIQRFYKGTKKFYVSQGYKLVDAVVGSPLAKDKPIVLVNDGSD
                     KSVLRGADEVTSLGGMDKKVADQCISSASDKNTMPTITANDVEISVGDKFDNSMLNIV
                     ATDYYGNNLRPNIEGTVDTSKAGTYVLNVSAFDNFGQKCEINVNVKVIVNTSTKDPNS
                     YEFKAMVSNEMYNLVNSYRKEKGKRALRELDSLAGMANAWSKYMDEKKVFAHEIDGKN
                     AAEVFFGFGARSGENIAYLPMNVKSVYNAKDAKDIAKSIFDLWKKSSKYNENMLKEEF
                     YSFGFGMHISSKGEVNATMEFLNS"
     gene            25824..28127
                     /gene="slpA"
                     /locus_tag="KRH23_002277"
     CDS             25824..28127
                     /gene="slpA"
                     /locus_tag="KRH23_002277"
                     /inference="COORDINATES: protein motif:HMM:NF033435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-layer protein SlpA"
                     /protein_id="HHS5225555.1"
                     /translation="MNKKNLAMAMAAVTVVGSAAPVFAATTPSEDNAGKYTVVKDKYK
                     DIFDEVKKLVKENDAAIDAYLKENNSTDRDAAWTALAGTNSLNIINITVKDSDDDSVV
                     VPKTVVKTNTVVDTDYVENKLKNLDTDEYVDFDITTKASTVSSTKYTAANIYDLAANN
                     GKIIIDALKNVTEKQLKDGGILGEVAKTISGATTPSAPTGDTFASYFTVGTVKTVNGK
                     VALEINIAEPASTVLVKTDAELTTSPTTQQKMSFANAKITLTEGDDRLDFSKPSIVDG
                     ALGDFAKAAATTTPGKQQTINVRVINAKQETVKATDYDALKAVVSKYKFDSTEIGRVY
                     DEAKDLNDKDKLDGSSYDKDGTYKAVFFAEGKRLQGFSSYGKFSTDEAESGLADGNAA
                     LKLVIESTDEDDFIDGLKDLKELNNSYSDVESVAGDDRIETAIELSKSYYNNSRSNNS
                     DTLYTGAVDNVVLVGSQAIVDGLVAGPLAAEKEGPLLLSSKDKLDNNVKNEIKRVMGL
                     SSTNSIDSKKKVYIVGGENSVSKDVQKAIEDMGVKVERLSGDDRYATSLKIADKVELN
                     DKDKAFVVGGTGLADAMSIAPVASQLVGKEATPIVVVDGKADKLSSDASDFLDSAKEV
                     DIIGGENSVSNKVKDSIKDAIGRSVDRISGDDRQATNAEVIKEYYENDPKNVKNIFVA
                     KDGSTKEDQLVDALAAGAIAGNLGLSAGEDEVSPAPIVLATDNLSSEQHVAISKVVND
                     KQTNKIVKVGGGIADSVINKLKDLLGM"
     gene            28393..30735
                     /gene="secA"
                     /locus_tag="KRH23_002278"
     CDS             28393..30735
                     /gene="secA"
                     /locus_tag="KRH23_002278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002842775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006605 - protein targeting [Evidence IEA];
                     GO_process: GO:0006886 - intracellular protein transport
                     [Evidence IEA];
                     GO_process: GO:0017038 - protein import [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HHS5225556.1"
                     /translation="MSVLDMILDKTDEIEIKKLNNIVDKIDALENKIQLLSNDELKNM
                     TGIFKSRLNKGETLDDILPEAFAVVREVSKRILGMRQYRVQLIGGIVLHQGKIAEMRT
                     GEGKTLVGVAPVYLNALEGKGVHVITVNDYLAQRDKELMKPVYEFLGMKVGVIINGQQ
                     PSERKLQYQCDITYGTNNEYGFDYLRDNMVTKKIDKVQRELNFAIVDEVDSILIDEAR
                     TPLIIAGSGEEGTKLYELANAFIKTINDEDFEMDRKDKTIALTQSGLSKAESFFGIEN
                     ITHIDNIEIFHHVNQSLRAHKLMSIDVEYVVKEDEILIVDEFTGRIMDGRRFTDGLHQ
                     AIEAKEGVKIKDESKTMATVTFQNFFRLYSKLSGMTGTAKTEESEFESTYKINVVQIP
                     TNKPVIRADLHDKVFKTENAKYNAVVEEIIRINKTKQPVLVGTVSIEKSEKLSRLLKK
                     RGIKHQVLNAKQHDKEAEIISKAGKLGSVTIATNMAGRGTDISLGAGDEEEEKIVKDL
                     GGLYVIGTERHETRRIDNQLRGRSGRQGDPGTSRFFVSLEDEVIKLYGGKTIEKILKR
                     MSTKEEEALESKALNRAIERAQKGIEGKNFEQRKNVLKYDDTINEQRKVIYNERNKVL
                     DDLNISDEIQKMVIEIIQESADKYLKKTRDYQGYFRYLYKIFMPADTLLIPRLDEKSV
                     DEIINQTYEISKRVYDLKKMMIGIKELEKLERKVLLEVVDTYWVEHIDAMDQLRQYIG
                     LKAYGQKDPFKEYAIEGYEMFEALNKNIRVSTVQYLYKFE"
     gene            31116..32987
                     /locus_tag="KRH23_002279"
     CDS             31116..32987
                     /locus_tag="KRH23_002279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp2"
                     /protein_id="HHS5225557.1"
                     /translation="MNKKNLSVIMAAAMISTSVAPVFAAETTQVKKETITKKEATELV
                     SKVRDLMSQKYTGGSQVGQPIYEIKVGETLSKLKIITNIDELEKLVNALGENKELIVT
                     ITDKGHITNSANEVVAEATEKYENSADLSAEANSITEKAKTETNGIYKVADVKASYDS
                     AKDKLVITLRDKTDTVTSKTIEIGIGDEKIDLTANPVDSTGTNLDPSTEGFRVNKIDK
                     LGVAGAKNIDDVQLAEITIKNSDLNTVSPQDLYDGYRLTVKGNMVANGTSKSISDISS
                     KDSETGKYKFTIKYTDASGKAIELTVESTNEKDLKNAKAALEGNSKVKLIAGDDRYAT
                     AVAIAKQTKYTDNVVIVNSNKLVDGLAATPLAQSKKAPILLASDNEIPKVTLDYIKDI
                     IKKSPSAKIYIVGGESAVSNTAKKQLESVTKNVERLAGDDRHMTSVAVAKAMGSFKDA
                     FVVGAKGEADAMSIAAKAAELKAPIIVNGWNDLSADAIKLMDGKEIGIVGGSNNVSSQ
                     IENQLADIDKDRKVQRVEGETRHDTNAKVIETYYGKLDKLYIAKDGYGNNGMLVDALA
                     AGPLAAGKGPILLAKTDITDSQKNALSKKLNLGAEVTQIGNGVELTVIQKIAKILGW"
     gene            33094..33801
                     /locus_tag="KRH23_002280"
     CDS             33094..33801
                     /locus_tag="KRH23_002280"
                     /EC_number="3.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000225 -
                     N-acetylglucosaminylphosphatidylinositol deacetylase
                     activity [Evidence IEA];
                     GO_process: GO:0006506 - GPI anchor biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HHS5225558.1"
                     /translation="MVDATLFFTPHQDDETLSMGSAIIEHVEKSDTHVILCTDGSKSI
                     IRKVLDDGGSCSYHIKDVHKYSLSESEFSKDRDEEFKDSCKAMGVKSSNIHIEENRAH
                     DGELSKEKAREIILKYLEEYPNARVKTVTPYKASGIHEDHRALGEAALELYEEGKIKD
                     LRFYVEPYDYIDFKKVNPNVKVWEVLTTQEEKLLSAMNAYKKWHPESGHYAIGYHSVK
                     SHFEELKSNKIQYVHAP"
     gene            33834..35978
                     /locus_tag="KRH23_002281"
     CDS             33834..35978
                     /locus_tag="KRH23_002281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HHS5225559.1"
                     /translation="MKASKKVMLLLTISFISTCLYTNKVSAATKDTLVGSGRWETAIK
                     ISQKGWSSSTNAVLVNDNSISDALSSTPFARVKDAPILLTQKDKLDNRTKLELKRLGV
                     KNVYLIGGINALSQDIEKELKLEGISFERISGNDRYDTSVKLAEKLDKEKKFSSVFVV
                     SGKSGLADAVSIGSIAAQEGMPIILSNPENGIKLADKLIKEKNINKSYIIGGKLSVSE
                     SVEQNLPNVKRISGNNRNETNAKVIEEFYKSTNLKNAYITKDGMRNQSDLIDSLAVGV
                     LASKNSSPVVLVGKELDSAQKDIMNTKIFDKITQVGGLGNESATKSIADMQEQTKYTV
                     ESIEELNVALKKADANDVIKFKAEKDKKVTDSFKLETKKAITIEFDGTYTQTITIDMP
                     NGDINNFGKIDGSFIINNIKNNTLVNKGDINQIDVYSKNGCRIENQSSGDIWLITILK
                     EAKNVYIENDGDIIKISNSSNDVTLKNYGSVDKISGNKELAIIGNKPRINDTIEDDKE
                     KASELYPEVKSCTPAQSNFIMLHISQEPKYSDYAIYYRVVKSKPSAIKIGDKIDIDDW
                     DIVKGTTPFKVNAINGSYIECVEIDKSNKSVRRWGRTGETNDGVKVEEVANGLDVDVN
                     IIGENVKITTPKANLDCKIYYRISEIKPTAMNVGEKINLSSWDSVIGNYVELRFNDVK
                     GKYIELVELDNSNNLVTRWGKTDKIVVTSSEI"
     gene            complement(36078..36485)
                     /locus_tag="KRH23_002282"
     CDS             complement(36078..36485)
                     /locus_tag="KRH23_002282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HHS5225560.1"
                     /translation="MILKKHRETILYLFFGAFTTLVNIVSYLFFTRVILFNFMLANSL
                     AWILAVLFAYVTNKFFVFESKRIEIRFVFKEFLSFVSFRLLSGVVEMLIMYVMIDLLF
                     VNDIIVKVFTNIVVIVLNYLFSKMIIFKKDNIN"
     gene            36712..39123
                     /locus_tag="KRH23_002283"
     CDS             36712..39123
                     /locus_tag="KRH23_002283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding cysteine protease Cwp84"
                     /protein_id="HHS5225561.1"
                     /translation="MRKYKSKKLSKLLALLTVCFLIVSTIPVSAEKHKTLDGVETAEY
                     SESYLQYLEDVKNGDTAKYNGVIPFPHEMEGTTLRNKGRSSLPSAYKSSVAYNPMNLG
                     LTTPAKNQGSLNTCWSFSGMSTLEAYLKLKGYGTYDLSEEHLRWWATGGKYGWNLDDM
                     SGSSNVTAIGYLTSWAGPKLEKDIPYNLKSEAQGATKPSNMDTAPTQFNVTDVVRLNK
                     DKETVKNAIMQYGSVTSGYAHYSTYFNKDETAYNCTYKRATLNHAVAIVGWDDNYSKD
                     NFASDAKPESNGAWLVKSSWGEFNSMKGFFWISYEDKTLLTDTDNYAMKSVSKPDSDK
                     KMYQLEYAGLSKIMSNKVTAANVFDFSRDSEKLDSVMFETDSVGAKYEVYYAPVVNGV
                     PQNNSMTKLASGTVSYSGYINVPTNSYSLPKGKGAIVVVIDNTANPNREKSTLAYETD
                     IDGYYLYEAKANLGESYILQNNKFEDINTYSEFSPCNFVIKAITKTSSGQATSGESLT
                     GADRYETAVKVSQKGWTSSQNAVLVNGDAIVDALTATPFTAAIDSPILLTGKDNLDSK
                     TKAELQRLGTKKVYLIGGEYSLSKNVQTQLSNMGISVERISGSDRYKTSISLAQKLNS
                     IKSVSQVAVANGVNGLADAISIGAVAADNNMPIILTNEKSELQGADEFLKSSKITKSY
                     IIGGTATLSSNLESKLSNPTRLAGSNRNETNAKIIDKFYPSSDLKYAFVVKDGSKSQG
                     DLIDGLAVGALGAKTDSPVVIVGNKLDESQKNVLKSKKIETPIRVGGNGNESAFNELN
                     TLLGK"
     gene            39426..41003
                     /locus_tag="KRH23_002284"
     CDS             39426..41003
                     /locus_tag="KRH23_002284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp5"
                     /protein_id="HHS5225562.1"
                     /translation="MKAPKTILTILTIALTLSSISIIPSYALTEEKLIGNGRYETAVK
                     ISQKAYSSSSNVVLVNDNSLADALSATPFAKAKGAPILLTESDKLDDRTEKEIKRLGA
                     KDIYLIGGTAVLNKDIENKLKSNGLNVERINGKDRYETSLILANKLKDIKDIKEVAVV
                     NGEKGLSDAVSVGAPAAQNKMPIILSSPKDGVEAFDKFIRDEKVIKAYVIGGTTSVSR
                     AVEKSLPNAERVSGKDRNETNAKVIEKFYTDTNLSNLYVTKDGSKNENQLIDSLAVGV
                     LAAKNESPVVLVGNKLNTKQRDILSTKKLNTITQVGGNGNEEAFDEIKSLQEKTVFEA
                     KTVEELTDMINIASPNDIINFKPKENTVNEAFRMVTNKPITVNIKGDCSKTLTVDMPN
                     GEVNNYATLVNVIVRNIGEGGFNNHDTITILSVRDKNGRVIENTRNSDIDTLMILASA
                     NDTKLINDGYIGKLIDNSSNSDITNNGTIDKKVNQVEDLEAKVDSIEKAIDSISQKVN
                     KIQDILDKLGFLKKFLS"
BASE COUNT        16973 a         4553 c         7540 g        12144 t
ORIGIN      
        1 gtgtttattt tattatttat cttttttaat tgatttaata ttttctttga ttttatttaa
       61 aatatctgta tgcttattag agcttatgtt ggggaatgct ttgattatac gtctatgaag
      121 taatttgtgg ttagacagca aagtattaag tttatttttt agctcatcaa tacgattttt
      181 agcatagcga tagttttctt tttccttaag tatttcaaac ctatcttcca aagtatccag
      241 tctattttca actaaagatt caagtttgtt ttctatagtt tcttgtgtaa taagtttgta
      301 gtattctttc ttatctttta attccttaat tataagattg atttgtttta acttaccatt
      361 taattgtaaa attgtatgga ctgtgataac taaatctaaa acaaaataaa tttctataga
      421 tatagcaaat ataaatagca catttttaga gatagagtta ataaaatcaa ccacaatagg
      481 atgtactata agcattacaa tcaatgataa tacaccaaac ataagtgaat tttccagaca
      541 aactcttccg tgaatattaa atttatgttt agaataatcc caccaagtca tattaaatat
      601 tttttctaaa ataaagctcg tacagtactc cattatgcta gttataatta tactaaacaa
      661 aaataacaaa ggaatattgt gtacaaaagg agtcaaggta gcaactattg ctaatgctcc
      721 aaatccatat atagggcaaa atggaccatt taaaaaacct ctatttacaa attgtttttg
      781 taaaactgaa caatatgtag tttcacaaca ccatcctata aagctataaa ttacaaaata
      841 aagaaattga atataaaatg tactcataag cacctcattt ctagttagta taacactata
      901 tactcgatat tttattttta tgattaattt gctaaattca atttacatat tgattatacc
      961 aatttataga aatttatcaa atttaattac agttagaaca ttataaacat ggttataata
     1021 atgaaatttt atttaaaata aataagggtg tcaagtataa tcaaactaat agttgtagat
     1081 actctacact atgttagttt aattacattt gacaccctta tatttatact atgactattt
     1141 acattcgaaa ctagagcaac atgtttcaat ataaaggttt actctatcag tttcaggagc
     1201 aaccaatata ttatcaagtg tacataagct accatctttg ttgtatttac aattttttac
     1261 agtacaaact aattcctcac aatttctatt attaacgttg ctagataaat tactataaat
     1321 agattcatct aaaaatgaac tacaacaagt atgtctgtca ttgtgagctt tttcaccatt
     1381 tataaaaatt ttatctgcat aacatatatg gctgttgtta tgtgaacagt taattacatt
     1441 acagtttatt ctttccaaag ttattacctc ctaaacgatt atttattata aattatgtcc
     1501 atataattac aagaatataa ccattaagag aaaactacct tttagaaaat atctattctt
     1561 agagtaattt gaaatataaa tatattttct tctaaaattt acctaaattg tataaaaact
     1621 tacagcttgg agaaaataat agaaaaagga ggcgtaatca atgtttgaaa agaagaaaaa
     1681 agaattattt ccttggaaaa tatctgcctt aatactggtt ggagtatttg tattaagtag
     1741 cggagtttat atagggacaa gattaaaaca caatggagtt caaactggtg aagttgtaag
     1801 tactagtgcg aatatgaatg aaaagtcaaa agaagctttt ggattaaata aaaattgtga
     1861 agtttggctt caaagtgaag gcgaaaatga aactaactat aagagaacac ttacaatggc
     1921 aggaatagtc ccagagtcat tattagataa gacgaagtca gaaatagtat catattttaa
     1981 aaaagaatat ccaactaaaa aaataaagag tatggataaa aatgaaatca tattggtaga
     2041 atctaaatat agtgataata aagatgtaca agcaatggat gttactataa aaggtaaata
     2101 tactattgaa aatgataatg gaaatatagc actatataaa tatgatgata gtggaagtaa
     2161 aacattagta gaaaaaacaa aaataagagt agattcactt cctaaaacag ttcaagatga
     2221 aatcaaaaaa ggtgtagtta tggatactga agaagaggcc tattcaagat tagaagactt
     2281 tgcaagttaa tagtaaatta atattatttt aagttaaata ctaagtaaat taataataaa
     2341 taatttaata ttaaatagat tagtattaaa attgtagtca catttaattc ctataaaaat
     2401 acaataattt atttgtaata aatataaaag ttatattgag gtaaaatctt gctttgatat
     2461 aactttttta tttgatttta tattttacat agagcatttt atgatttgtt aatattattt
     2521 atgatataat gatttagaac ataagttttt atgagaaata cattttggta tttcttttat
     2581 ttttaggggg aattttaaaa aatgataata ttggggattg acccaggtat agccatagtt
     2641 ggatatggta taattgaata caaaaatagc aagtttaaag taatcgatta tggagcagtt
     2701 acaacacctg cccatatgaa tatatcgaga agattggaac ttgtgtataa aggaattgat
     2761 acaatagtaa agaattacaa tatagatgaa gttggaatgg aagaattatt ctttaacaag
     2821 aatgtaaaaa cagctataac agttgcacaa gctagaggtg ttactatgct tgcatgtgct
     2881 cataatggga agcctgtata tgaatacact ccacttcaag taaaacaagg tgtagttgga
     2941 tatgggagag cagataaggc acaagttcaa cagatggtaa cttcattttt aagtctaaaa
     3001 aaagttccaa aaccagatga tgttgcagat gctttagctg tggctatttg ccatgctcat
     3061 tcaaacaaac ttgaaaaaac tctaaagaat ataggtggta agtatgtata gttatataaa
     3121 aggtacagta gaagaaattt atatagacag tatagttgtt gaaaataatg ggataggata
     3181 taaaataaat gtatcatcca atacaataat gaatttacaa gtgggagaag ccacaaaaat
     3241 atatactaaa ttaattgtaa gagaagatga tatgagtctt tgtggttttg taagtaggga
     3301 agagcttaag atgtttgaat tactaacatc tgtatctaaa ataggaccta aggtggcgct
     3361 ttcaatacta tcatttgcat caccagcgca gttaggagca tatattttaa gtgaagacat
     3421 tggaaaatta tccaaagctc ctggtgttgg taaaaagaca gcagaaagaa tcgtcttaga
     3481 gcttaaggat aaggtagaca aaaataacat agagtttgaa ccaacgttat tatcacaaaa
     3541 acctaccttg atatcacaag atgagtctgt agatgcactt gtagctttag gctatacttt
     3601 gtcggaatca aaagaggcag ttcaaaaatg taaaaaagat ggtatgaata cagaagctat
     3661 tataaagaaa gcacttacat atataatgag taaatccttg aaatagtatt tggattttat
     3721 aatatttgga ttttaaaaca atatttaagg agtttatgta aatttgaaaa tatataaagt
     3781 agattttcaa aagtacgaaa ggaggggtat aaatgcaagg ttttgaagat gaaaatagga
     3841 taataacttc tacaatgaag atggaagata tagatataga aaacagttta agaccaaaaa
     3901 ctttagaaga ttatttgggt caagaaaaat ccaaagaaca acttagtata tttatagaag
     3961 cagctaaatc gagaaatgag cagttagacc atgtgctttt atatggacca ccaggtcttg
     4021 gaaaaactac actagcaagt ataatagcca atgagatggg ggtaaattta agaattacgt
     4081 caggacctgc aatagaaaga gctggagatt tggcagccat acttacgaat ttaaatgaaa
     4141 atgatgtttt atttatagat gagattcata gaatcaatag aagtgttgaa gaagttttat
     4201 atccagcaat ggaggatttt tgcctagata taataatagg gaaaggacca tctgctagaa
     4261 gcataagact tgatcttcct aaatttacac ttattggagc tactacaaga gctggtatgc
     4321 ttacaaatcc acttagagat agatttggtg ttatttgtaa attggattat tatacagttg
     4381 atgaactttc aaaaatagta cttaggtctt caagcatctt agatgcagag atacagtcta
     4441 atggagcatt agaacttgca aaacgttcaa gagggactcc aaggatagca aatagattac
     4501 taaaaagagt tagagatttt gcacaagtca gagctgatgg aaaaataact gataaagtgg
     4561 caaaagatgc tctggaactt ttaggagtcg atagtttggg tctcgatttt gtagatgaga
     4621 agcttcttat gactataata gaaaaattta gaggaggacc agtgggttta gatacattgg
     4681 cagcttctat cggagaagat agaaatacaa tagaagatgt atatgagcca tatttgcttc
     4741 aattaggatt tataaataga ggtcctagag gaagagtagc catgccatta gcatatgaac
     4801 acttaaaaat tccatatcct aatgaaaaat aaaaatagat tatacgagta tttataaaat
     4861 aaaagagtca ttaaattaaa atatttctaa aatggctaaa aattcaaaca tatccacaaa
     4921 atggtaatta tatctgtaga tactgtggat aaacacgata aaaattgtgt gtattgtatc
     4981 tatatattgt ggataagaca tgtatatcgt ggaaaaatat ctatatattg tggatatggt
     5041 gtctgttaaa aatagcaatt tcttgataga ttatggtaat attgtggaaa ataagttgtt
     5101 tttttgatat tattgtagct ggagaaattt taagagagga agtttaacat tgaaaacaag
     5161 tgattttaaa tttgacttac cacaggaact tatagctcaa gttcctatag aagatagagc
     5221 tagctcaaga ttgatggtat tagataaaga gacaggtaat attgaacata aagtatttag
     5281 agatataata gaatatttaa atccaggaga ttgcttagta ttaaataata ctagagttat
     5341 accagctaga ttaataggag agaagattga aactggaggt aaaatagagt ttttattatt
     5401 aaaaagaaca gaggaagata cttggcaggc tttagtaaaa ccaggaaaaa gagcaaaagt
     5461 agggactaaa ttttcttttg gaaatggaaa gctaattgga gaagttgtag atttatcaga
     5521 tgaaggttca agaattataa aattccatta tgatggaatt tttgaagaaa tattggatga
     5581 acttggaaat atgccactac ctccatatat cactgctaga ctagatgaaa aagaaagata
     5641 ccagactgtt tattcaaagc ataatggttc agcagcagca cctacagcag gattacattt
     5701 tacagaagaa ttgttaaata aaataaaaga aaaaggtgta gatatagcct ttgtaactct
     5761 acatgttggc ttaggaactt ttagaccagt aaaagtagag gatgttttaa atcacaagat
     5821 gcattcagaa tattatatgg ttagccaaga agcagctgac aaaataaata gagcaaagga
     5881 aaatggaaaa aatgtaatat gtgttggtac taccagttgt agaactatag aatcagcttg
     5941 taatgaggat ggaaagatga aagaaactag tggatggaca gaaatattta tatatccagg
     6001 ttataaattt aaagttttag ataaacttat tactaatttt cacttaccag agtctacact
     6061 aataatgtta gtaagtgcta tttgtggaaa ggataatgtt ttaaatgcat ataatgaggc
     6121 agtaaaagaa agatatagat tcttcagttt tggagatgct atgattataa agtagggagg
     6181 taatggatgc atagtttaca aaaacaaaaa aagaataacc ctatattaaa gattgctttt
     6241 atatttgaac gtgttttagc agtagtagtt ctaatagcag tatttttagg aactatagat
     6301 gttctaagac ttatgtgggg agcatatata gttgattttc aaaatccagt acaatacagt
     6361 cagcttaatg attttttagc acaaatatta cttttagtaa taggtgttga acttgtagta
     6421 atgctatctc ttcatatacc aggagcattt attgaggcat tactttacgc aattgctaga
     6481 aaaatgttgc tactgcctaa aaatgaaggt atgatagatg ttttaatagg agttatagct
     6541 atagcaggac tatttgctat aaaaaagttt ttagtaacaa aagacaagag tgctcttaat
     6601 ataatgagta ttcatgatga agaagcaatt aaggaacaac agaacaaaga agacgaagat
     6661 aaatctattt agacaataaa ttatatgaat agcttattac aaatatatct taagaaataa
     6721 tgagaaataa atatgattaa ggagaacttt atgtacgcag taagatacga attgataaag
     6781 acttgtaagc agagtggtgc aaggttagga agattacaca ctccacatgg gattattgaa
     6841 acaccaatat tcatgccagt tggaactcaa gcaactgtaa aatctatgac accagaagaa
     6901 ttaaaagaga ttggttcaca aataatactt agtaacacat accatttata tatgagacca
     6961 ggtcatgaac ttataaaaag agctggtggt cttcataagt ttatgaattg ggataaacca
     7021 atacttacag atagtggagg gttccaggta tttagtctag ggcctttaag aaagataaaa
     7081 gaagaaggtg tagaatttag gtcacactta gatggttcaa aacattttct aactccagaa
     7141 aaagctatgg aaatacaaaa tgcattgggt tcagacataa tgatggcatt tgatgagtgt
     7201 gcaccatacc catcagatag agaatatgta aaaaattctt tagaaagaac aacaagatgg
     7261 ttaaaaagat gtaaagatgc ccataataat accgacaagc aagctttatt tggtataata
     7321 caaggtggga tgtataaaga cttaagggaa caatcagcga aagaaataac taatattgat
     7381 ttaccaggat atgctattgg tggacttagt gttggagaac caaaaccact tatgtatgac
     7441 gtgttagagc atacaactcc acttatgcca aaggataaac caagatacct aatgggagtt
     7501 ggtagtccag atgacttagt agaaggtgtt ataagaggag tagacatgtt tgattgtgtc
     7561 ctacctactc gtatcgctag aaatggaact gcaatgacta gccaaggtaa agtagtagtt
     7621 agaaatgcaa cttatgctga agactttact ccacttgacc ctgaatgtga ttgttatgct
     7681 tgtaaaaact attcaagagc ttatataaga caccttataa aagcaaatga aatattgggt
     7741 gcaagattaa taactactca taatcttcac tttttattaa atttaatgaa acaaataaga
     7801 caagcgataa tggaagatag attacttgat tttagaaatg aattttttgc aaaatatgga
     7861 tatgaaatat aggttttgca ctattaatta taatcatttt aatatataat attcaatagt
     7921 actcaaagat agagaaagta aattgttata taaacattta ttatgattta caaaagagta
     7981 taatttacaa aggagtgaaa aattaatgcc acagcaacaa ataattatga gtataggtct
     8041 atgggtagta gtaatcgcaa tcttttattt cctaatgatt agacctcaaa agaaaaaaga
     8101 caaacaatta aaagaaatga gaagtagcct aagtgtagga gacaaggtca ttacaatagg
     8161 tggaatagta gctaatgtag ctaaagttga agatgatgtt gtaatattag aattaggacc
     8221 aaatagaact aaagttccat ttgaaaaatg ggctatagga actgttaaat ctaaaaaaga
     8281 agaaatagaa gaagactaaa ttagtaattt aaaagccttt tctcgaatat atattaattt
     8341 gagaggaggt ttttttatgg gaaaatctaa ttatattttt aaaggtctag gatatgcata
     8401 tataataact ttggctgttt tattagtgta taacttattt ttgacattta cagatattgg
     8461 tggagataat ataactatgg tctcatcatt tataactact atttctgcag ctataggagg
     8521 gttttacact tcaaaacaca tgaaagaaaa aggacttatg tatgggcttt tagtaggact
     8581 tttgtacata gtatgtattt ttttgactgt gtttttagca caagaaaagt ttgtatttga
     8641 agtagggatg atttataagt tattgttaat atcagcagca ggaggcattg gaggcgtatt
     8701 gggtgtcaac tttaaataga gtttatatta aagtagtttt atgatataat caataggaaa
     8761 caattagaaa tggaggcgtt gaaaatggaa aataaacatg taaaaacttt atctcaagct
     8821 actttaaagc aaagtgctgc aaaaggtgga tgtggagagt gtcaaacttc ttgtcaatca
     8881 gcttgtaaaa cttcttgtac agttgcaaat caagagtgtg aaagatagaa aattattgat
     8941 ttagttgttt gtaagagggt atctcaaagt gattctttta tcattatgag gtatcctctt
     9001 ttattttcaa ttattatata aaaatatata ttctatttat gtaaaattaa atttgatttc
     9061 ttatcgttta attatgcaaa aatatctaat catataagag catttatttt aaagtagcta
     9121 ctcttatatt ttatttttta tcaattacat gtattagaat aatttttaat tttaaactct
     9181 aatttatgat gatttttata atatgttata tattttaata tatggagata gatattaatt
     9241 tagtgatata tatttaagta ataagagtaa agcaaaaatt agtgcatagt agtatataaa
     9301 aatggagttt gaatactttt gttagtatat gattgtttag tagaaaatca ctataaaata
     9361 ggatttctat ctttgagcat aattatagag agctaagtag ggggaagggt ttcaagaaga
     9421 tattattagt gtttgtgtta gtaaattatg taaacacata aaatatattg aaaaataata
     9481 ttatatataa tattatttat gtgtgggaaa tacgaatata aaaaataaaa aataatattc
     9541 ggaggacata aatatgttaa gcaacaaaaa gagaagtatg gcaatagtaa tggcaggtgc
     9601 tacagttatg agtgcagcag caccaatatt cgcagacaat actgtgacag aaaatgttga
     9661 taaaaattac acagtaagtg cgaaagattc tgctaaacta atcgaagagg ttagaaaagc
     9721 attagaagtt aagtttgaag atacaaaagc aggagcaaat gtaaatgata gagtttacga
     9781 tataaaagta gacaatgtaa acttaactaa tgcaactcaa ttacaaaata aaataaactc
     9841 tttaacagaa gggcaaagtt taaaagttac tattcaagat aaagggcatc aagtgttagg
     9901 tggaaaagta gttgactata aaattgaaaa ctacaaaact gctcaagaaa tagtagatgc
     9961 agttaatgct tacaatgcaa ctttagcaga agattctgat aacaagttaa cagcaactat
    10021 aaaatctaca aatacagttg aagtaaaaag agcaaaagat tcagcaaatg ttattacatt
    10081 aaatgtagga gaccaacatt tagatttctc aaaagtgata acatcagaag aaggtacttt
    10141 tgaaggttat gaaaagagtt atagtgacat agattcaaaa gaattacata cgataacagt
    10201 taaaaacgca gatttacaag acatatcagc agaagaatta tttgatggaa ttagattaac
    10261 tacattagga agagaaatag ttaataaagt taaaaatgga tatgctttaa catttgaaaa
    10321 tgaagcaatc cttactcaag aacaagaaga tagtgatgat aaagataaac cagaaaaatc
    10381 aagttttgat atagttttaa gcaaggcaaa tgaaaagcca gaaacaataa gtgtttcaag
    10441 taaaaaccat aagttagtta gagacttaca caaagtatta actgatgtaa aagatggaaa
    10501 agaattaaaa gtagaagttt tatctggtga ttcaagattt acaacagcag tagaagttag
    10561 taaagagaga tttaaagatg gagaagcaga agctataatt ttagttggag aagatgctat
    10621 agttgatgga ttagcatcag caccacttgc ctctcaaaaa aatgcaccaa tattattatc
    10681 taaaaaagat tcactaccat cagaaataga agctgaaata ttaagagtac ttggaagtaa
    10741 tctatcttct aagaaaatat atatagtagg tggagaatct aaagtatcaa aagaaactga
    10801 agaaaaactt tctaaattag gtgtaagtaa agttgagaga gtttctggag aagatagatt
    10861 tgaaacttct ttagaaatag caaaacaatt aaaagataca tttaagactg cttttgtagt
    10921 aggtggaaat ggagaagctg atgctatgag tatatcagct agagctgctc aatttggtgc
    10981 tccaataata gttacaggta acgaattaga tgcaaatgct gaaaaattat taaaaggaaa
    11041 agaattagaa atagtgggtg gagaaaattc tgtatcaaaa gaagttgaag acaaattagt
    11101 tgatatagat ttaaataata aagttgaaag attagctgga gaaaatagaa aagatactaa
    11161 tgctaaagta atcaataaat actatgcagg tgcaactaaa gcatatgtag caaaagatgg
    11221 ttatgtaggt ggaaatggac aattagttga tgcacttaca gcagcaccac ttgcagctag
    11281 ttcaaaggct ccaatagtat taactacaga agaactttct aaatcacaag aagaagtagt
    11341 tgagttaaga cttaagaatg ctactaagtt agtacaaata ggtgaaggaa tagctaaaaa
    11401 cgctattgaa aaaatagcag aaaaaataaa cttatttact aagaactaat aagatatagg
    11461 aattaatatt aaaagtttat ttagataata tatgattata caatgcgtta atatgtaaga
    11521 catagtgtag atattataaa atatacaaat aacaagataa aataataaaa ataaggtgtc
    11581 tcatttagaa ttagattgag ataccttatt ttattttttg attataatgt tgagaaattc
    11641 atattgcaaa aattattata aaaagatact tcttataatg attaaacata ttactaacat
    11701 aaattatttt gaacttataa cttaattaaa taaaataaat tataatgttt tgaatttata
    11761 gagaataaaa actttaggta tattgtttga gttgtatgga taactatggt atcatatata
    11821 aaatatggta acaaaattgt aacttttgat taaaaataag tatgagtact aagaaaaaat
    11881 gtgaaaagta cattgggggt agaaaataat atgaagaata gtaaaaagat attagctata
    11941 ggacttacac tatttttagt aatggtaaat actcctatgg taaatgcgtt gacatcagtt
    12001 gagcaaataa aagggaatga cagatatgag acagcagcaa aaatagcaga taagcaaaac
    12061 tacaatacag caatactaat caactcagat aatagcttag cagatggtct aagtgcaagt
    12121 ggtttagctg gagccttaaa tgcgcctatt ttgatgacaa agcaaaacca gattccaaac
    12181 acaactatgg aaagattaaa caaagcaaag actgtgtata taataggctc agaatcaaca
    12241 ataagtaaaa atgttgagaa tcagttacta tccaaaaaga aggttgtaca aagaatattt
    12301 ggtgaaaata gatttgatac aagtataaaa atagctgaaa aaatcaaaga aattaagcca
    12361 atagataaag taattatagc caatgggttt acaggagaag cagatgcgat aagtgcatca
    12421 ccagtagctg ctagagatgg agtacctata atacttacag atggaaatag tgtgggattt
    12481 gacacgacag gcttaaagag ttatgcgctt ggttctagtg aaataatcag cgacgaatta
    12541 gttaagagca caaattctat tagattgggt ggcacagata gatttgaaac taataagata
    12601 gttatacaag agttttataa aaatagtaaa gaattttatc taagtaaagg cttacaatta
    12661 acagacgctt tggctgcctc tacaatagca aaaaatgctc ctgtagtttt agttgaaaat
    12721 ggcagtaaca agagtatttt aagtggtgca gacaaattga ctgtactagg aggcataaat
    12781 cagaatgtta tcaagcaatg tataaatcaa gcttcaccaa atcaacaagg tttatattac
    12841 aatccaaatg atagagcatt taaagagaga ataaagggta aagtatatgc tcttacaaag
    12901 cagtatagaa aagagaatgg agtaagagcg ttatctgtag caagcagatt agagggtcta
    12961 gcaaatgatt ggtctaattt aatggcaaat aagaagactt tatctcatac gataaatgga
    13021 aaaaattcat attctacttt tttgaaatac ttagattgga gtgagattaa acctggatat
    13081 atagcagttc aaggtgaaaa tataattaaa tataaaattc cagataaacc tgtatataca
    13141 aatagagatg cagatgatat aggaaacttt atttttaatg agtggaagac aaatccagaa
    13201 gaaggaacta atatgttgca taaagggtat gaaataatgg gatttggtat agctataaca
    13261 ggagataaga atctatatgc tacacatgaa ttttatggaa gatataaaga ataagaaaat
    13321 atacacaaaa ttatgcttgt aaggaagcta tataaataat taaattataa tggaaaataa
    13381 catttatatt aataaattaa tataaatgtt atttttttat aatttaatct aaaaaaattg
    13441 tattaaaaag tttaaatata gtataaaatg ggtaagaaag tagtgaaaat taaatggcaa
    13501 aattagggaa atctaatgac gcaaaactat agggattaaa gcttttaaag ccatatcagc
    13561 cagttgctaa aaagagtaaa gtctttttat tttataatta agattctctt tgagtgtctt
    13621 tttttattgt ctgaaactta tagtatttaa attcatgaaa aattagatat ttattaaggg
    13681 aggattgtta tttcatgaaa aaggcaatat cttgtgtact agcagtatct atgtgtagtg
    13741 caccactaaa cgtttttgca gaacctatat tagaggggaa gctaagggca gttgaaaaat
    13801 cagttacaga aaagttaagg gggagtcttg aagtagattt aaatttttca ctgccaataa
    13861 aaaatagcga gtcagaaagt atgactaata tgcagttacg attaaaagat gatagtaaca
    13921 atagtggaat aataaagctt ggagaaaaag attcaggaac agtaaatgtt gggacagata
    13981 atatagaata tactataaaa aaattatctg caagtagaag tgaaataaaa aataaagatg
    14041 agaatgtatc atattatagt attgtattta ataatttacc tgttgggaaa tacaatgtag
    14101 aagtctctgg agctggattc aagaacaaag aaattaaaga cattgatata tcaagttatt
    14161 cacaaagagt cttattaagc aatagagcaa gtgtagataa taaaaatgaa cctttaaatt
    14221 atgaattgtt cttaatgggt gatgtaaatg gagacggtaa agtagataag agtgattata
    14281 ataaggtttt agagaatata gattcaaata aaagagaatt tgatttaaat agagatggaa
    14341 aggtagatat tgttgactta gattatgtac agaaaaattt aggacaaagt gaagatgcaa
    14401 aaagcctaga aagtatagta tctaccaatc ctatagtgga tacaagtaag gttgaattaa
    14461 aaggaaatag tgatgtagat attaatggta atgtagaaaa tttatttagt ggagaaaata
    14521 atggagttac aatatcttca aaaaatgatg aaatatctga ggaaaaacca gcagtaatgg
    14581 atatagcttt atcagaagca cttaatatgg aagtcatcaa tataaaagct ccagaaggta
    14641 ctgctccagc aaaaggaata gttgaggtta ctgacaaaga tggtaatgtt caacagattc
    14701 cttatgaaaa caaagaatat atgaaaaact taaaagatga tgagcaacaa gaggaagtaa
    14761 ataacgaaca agaagaagta aatcaagaag aagtaaataa taaagatgaa aatataaacc
    14821 agactgataa taactcaaat aataaagatg aaaataatga taaacaacag gaaaatagcg
    14881 ataaacaaga agtaaactct aataccaatc aagataaaaa taatgataaa gaaaattcat
    14941 caatggataa acctaattca gatgaagata ctccaaaaga agagggtaat atcagtaaag
    15001 atgataactc tacaacatct acatatagta ggtcagcatt agaaacatat gcagatgttc
    15061 aaaatagtga tatagtaata aatcttggta aacaagtagc agtaaaaaag ataactataa
    15121 aaataacagc tacaacagca aacgatagaa atcttgcaga aatatcaaaa gttgaatttt
    15181 taaacaatgt atataaagaa ataccaaagc cagagatgaa catacctaaa ataaataaaa
    15241 tatcgactag cactgctgtt ggaaatgaaa aagtatcttt ttattggaat aatgaagtaa
    15301 atgtatcagc atacgaactt atactagaca aaattgatag taagggaaaa gtattatcta
    15361 ctaaaaaatt acaaactagt aaaaatacaa tagaagttag agatatagaa gcatatggac
    15421 tatatagagt tagcatacaa tctttaaatg gagattggtc tagtggttat aaagatgcaa
    15481 caccagaaaa cttagacgga gtaccagaaa atgtagattc aaactataaa cctatacaat
    15541 ttagcccaga tagtatatta gaatttcaag ttgttccaga cacaaaacca gaaccaccag
    15601 aaggtataaa tgttaaaggt aaatttaaat cccttgatgt aagctggaaa actcataaac
    15661 aagctaaaga ttttgacttg tactataaag aaaaaggctc taatgggtct tggataaaat
    15721 acaatgataa gcttattcgt gggacaagtt caaagataga aggtcttaag gataatacaa
    15781 catatgaagt tagaatgaca gctactaacc acttgggaac tagtgtaatg tctaaaacat
    15841 atataggtac aactgaaagc atggatgcac caacaacacc taactataga ttaattaata
    15901 ctcctaaaga gaatggtgga tttggaatac caacaaatca cattgtagat gttacttatc
    15961 cagcaggata tgacaaaagt gaatatagtg ataaaaatcc atttgataaa ttcaatgtag
    16021 tagatgggga ctttacaaca cattggacat ttccaacata taatgcagct gagggaacga
    16081 atagaggacc aataataact tttgataaat cttatactat ggatactttt atggctacac
    16141 ctcgttttga tgtttctgat aagacaataa atgactttga ggtacgatat tgggatgaaa
    16201 atggtcaatt acacaatctg ggggatgttc cttttgaaac aaagacagac cctgtaaata
    16261 ataataagta tgtaatggtt agattaaaag aaccaataac tgctaccaag atacaagtaa
    16321 gtgtttgctc atcttattca tataagtcta atatatcaga acttaagttt tatgagtatg
    16381 acagtataga agatgatgta agaaatctat ttatggatga cctacaagtt gaattaaaag
    16441 aagatgtaac tcaagaaaaa ataactaaat taaaagatag attaaatact ccagataaag
    16501 ctagtggaga atatcatcca tataagacag ttattgagag agaattaaaa ttagctcaag
    16561 acttatataa cgatagagcc acacttactg atgtaacgac tgtaaatcaa gaaataaata
    16621 aattaggaaa atataaagat aaaaatggac agtatactgt aaattccaat aatttaggta
    16681 tgcaaaatga ctggcaggca ttaggagtag ctgctagagc aggagatgaa atcacagtat
    16741 atgttggaag taaaagtgga aaaactccta agttgatata tacacagtac tatggagaat
    16801 ctggtgcata taagagtgga gaaataaatc ttaacactgg aaaaaatgta attcaattaa
    16861 gcaaacttca tagtttagat atagaatgtg gaggaagttt atacataaga tatgctgaag
    16921 atactccaag tggaggagat ataaaagtac gtgtagcagg agctactaag ataccacatc
    16981 ttaatctaaa tggaacaata aatgataaga gtcctgcggg agtttctgaa tctaagaaaa
    17041 agataaaagc atatatagaa gaattagcta aatataaaga tgctgtaaaa ggggaaccat
    17101 attatccagg aacaaatgtt ggtaattcat atggatattc agaaaaaact ggtgtgttaa
    17161 acactacaga tattgaaagt gataaagtaa cattaaatgt tcctgcaaca gctgtatatc
    17221 aagggatatc aaaaggaaat gctgatttaa atacacaagt agatagatta tataatagta
    17281 tgcttgcatg ggaacagata atggatttag tttactcaga aagaggagta tttaaaacac
    17341 aagatttaga tggtaatgga actgtagatg ataatgaatt taacttaact aaaaatgata
    17401 tggctccaaa atctcgtatg aacataaaat accaaagaat gtttatagga gcatttatgt
    17461 atgcttctgg attacatgta ggagtagaat atggttcagt tccagggctt atgaatggag
    17521 tacctttcca aatagatgat agtggaaaag ctacaggagg aaacttattt ggatggggaa
    17581 taggtcatga gataggacat gttacagata ttggaaagat gacatatagc gaaactagta
    17641 acaatgtact tgctttactt gctcagacct ttgatgataa gacacattca agacttgaag
    17701 gttcaacaat ggataagata tatgagcatg taacttcaaa tagcttaggt ataccaagca
    17761 atgtatttga aaggcttgga atgttatggc aattacatct agcttatgat gatgatttta
    17821 cgggttcaat gttaaagaat aactcagatg ctgatttaag taatgataca ttctatgcaa
    17881 agatttcaag aaaatacaga gcactttcaa gtagtgaccc aattaatagt ttaccaaaag
    17941 accaaatgct agtagcaatg gcatcaagtg ttgttgaaaa agatttaaga gattacttta
    18001 aggcatgggg agtagaaatt acaccagaat taaacagtat aatggatagt aagaactacg
    18061 aaaaagaatc aagaaagata caatatgtaa atgacgaagc tagaagaaag attttaaatg
    18121 aaaatatagc tagtatggca aaagatacta aagtaagtgc tagtttttct gatggaatac
    18181 aaagtggttc tctagttaaa tctaataaaa tatctataga cctagatgta gataaggata
    18241 aagataagat actaggatac gaaataataa gaagtgatgg aaattattta gatggtgaaa
    18301 atggaacaca ggtaaaatac agaacagttg gatttgtgga tgcaaaagga aatagtaaga
    18361 ctaaatttac tgataatata tctcctctta ataacagagc atttacatat aaggtagttg
    18421 catatgatta tcacctaaat ccaacagaag aatttgaagt tggtactgta aaattatcag
    18481 atgaagggaa aataaataaa tcagcatggt cattcataac aaatactgtt tctgacggtg
    18541 atgttagaac tgaaaatgac tcacatggac cattacaaaa tcctgaaatt gataatataa
    18601 aagataatga tgcaagtact acatataaag gaaagataat aagtaaagca gagtggaaca
    18661 aagaccctca aaaagaccct gatataaatg tagaagaaaa tccatatata atagtagaca
    18721 tgaaagaaac attacctata gtaggactaa aatatacaaa accagaggca gaagctagga
    18781 agttctcatt aaaaggatta tttaacttta gaaagaatac tagtacaaca tacaatcctt
    18841 taactaatta caaaatacaa gtaagtaatg ataaaaagaa ctgggaagac gtaagtcaag
    18901 gaacttttga atatggacaa gatttagttg gtggaggaaa agaccaagat aatgaagcta
    18961 gagttacatt taataaagat ggtaaacttt ggacatacca agctagatat gtaaaactaa
    19021 tctcaaataa taagtctaat atagaagttg cagaattaga tataatagga cctccaggtg
    19081 ataatataga aattggcaca atgaataatg cagaccaaac tcgtactaat ggaattggaa
    19141 aattagcaga agattatgta tatcaaagtg atgactctag aacaagtgaa gatgaaacag
    19201 gtaagattcc agcgggttca atagttatta caggtgaata cagtggaaat ccagcattta
    19261 atttaccact acttatagat aaaaacaata agactatatc tggagaagca cttttatttg
    19321 cagaagttcc agaaaaaggt gaactaggtg aaatcagtaa aggtacatgg gtttactata
    19381 tgccaaaaga aaactttgat tctttaagtg ataaggttaa ggctgaacta tatagataca
    19441 atgaccttca agaagatact ccagtaggtc aaagatttgt aagtgataca atgtatgtac
    19501 ctgtaggagc taagaattat gatgagttaa agacaataag tcttactgat agtaatagta
    19561 aagctagaaa agctacaaga aatgctattg atatcagtaa taagaaggtt ataactgtaa
    19621 gcaataaagt aaagggtaat attgttagag ataaatagta ggtggaactc taaaaacgtg
    19681 aaaatactaa cactaacatt gtatatctaa taagattagg tactagaata tttttaaaat
    19741 agtagatatt aaaagtaaag tatataaatg taactataag tttagggtaa tttataaatt
    19801 aaatataaaa gctaggtgga taagtaaatt tatccactta gttaatgata gataaggacg
    19861 ggtgttaatg agtaaaagaa aatcttttat aagaactata gcagtatcaa ctatgtcagt
    19921 agctgtaact ggtagtgcta catgtgcata tgcagctcca gttttacaag gaacaaaaac
    19981 gtatgagaaa gtaaatacta tagatatatc tgtggactca gtagaaaaca tagtatattc
    20041 atttcaagcc agtataaaag tacaaggtga ggttgaagta gtagataatg agcagaaaga
    20101 aaagattact tggtctgata atataaaatc tcagataaaa agtggaaatg caaatgctac
    20161 ttgtagagca gaatacaaca aatcaagtaa tacaactaca ttagatatat atgttacatc
    20221 aaatgaagac ttactagacg gaaatagatt gaatatagga agaatatctg taaaaaaatc
    20281 tggcagtaac tcaaatgctg actataaagt tttaggaaaa ggaacaaatg ataaaccagc
    20341 tttaaaaatt gtaacatata acaacaaaac agtggattat gaaaatataa gctctgatga
    20401 aggattaata tttaccctta ttaatgagag tgaagtaaaa ccaattggtg gaactggttc
    20461 tagtaaaaat gaccctgaaa agtataaggt agagaaaagt gaagcacttg aatatttatt
    20521 aaacaatatt aggataaact attctattgt tagtaaagaa acacaagaaa gtggttcaaa
    20581 tgtaatatta aaacttggat tagcacaaaa aacaactaag ggaagaaaag ctacaataaa
    20641 caaatatgtt gaagttacac ttccaaaaag tttagaatac atagttgaaa atgaattatc
    20701 aaaaccagat gaattaccac cagataatgg caatggtgga aataatggcg gaggaagtaa
    20761 ttcaggcggc tcatctagtg gtggaagctc tggaggagga aattcaagtg attctacatc
    20821 taatgtcaca gtcaaaaaat taaaaggtgc tgatagattt gaaacagcta tcaaaatatc
    20881 tcaaagtggt tggacaaaat cagatacagt tgtaatagta aatggagaag ataaaagtat
    20941 ggtggatggg cttacagcta caccacttgc tagtgtaaaa aactcaccga ttcttttatc
    21001 atcaaatgaa aagcttcctc aaaaaactgt agaagaattg aaaagactaa atccatcaaa
    21061 agtaattgtg ataggtggaa acaactcaat gcccaattta gttgttgaag ctatcaaagc
    21121 tgtaaattca aaaatatcag tacaaagaat aggtggagat acaagatatc aaacttctat
    21181 taatatagca aaagaaatag ataagacgaa taatgtaagc aagttgtata taggagcagg
    21241 aaatggagaa gctgattcat tatcaatagc atcactggct ggtaaagaaa aaactccaat
    21301 agtacttaca caaaaagatg gtgtagatag tgaagctgaa caatttatta aatcaaataa
    21361 ggtgtcaaat atatatttta ttggtggaat agaaaaaata tctaacaagg ctattgaaca
    21421 agttggaaaa atagcaaaca aagatatatc aaaaaatagg gtggcaggtc aaactagaca
    21481 agagacgaat gccaaagtaa tagataaatt ctactctcaa tctaaactag atggagtcgt
    21541 agttgcaaat caagataaac ttatagatgc tttagcagtt ggaccattag cagctaaaaa
    21601 caattcacca gttatacttg ctacaaatac gttagataaa tcacaagaat cgtcattaaa
    21661 aggtaaaaat tcatcaaagt tgtttgaagt aggtggagga atagcctcat ctgtaataga
    21721 taagattaag agtttaattg aaaaataaat attaagtaaa tagaaaataa gaatgtattt
    21781 agatataaag ttatatattt aaatgcattc ttattttatt ttcattatct taacaatcta
    21841 ataatattga ggttaaaatg tataataatt tgagctatat taagtttaat tttaaataaa
    21901 gcagatatct tttatatata taaatataaa ttcaattttg aatatgttta aaaagaagtt
    21961 aaaaataatt ttttaaattt aataaaataa aacactaata tatagacgag atatattcat
    22021 atcatatata ctctataata tatggaaaat aaagagaaaa taaatgtaaa ataatcacaa
    22081 tataaatata aaatataaaa atcatcaggg ggatatgaaa atgaacaaaa aaatattatc
    22141 attaggtcta gcagtatcat taatcttagt aaacttcaaa agtgtaaatg catcatcagt
    22201 agtagaaaaa atatacggta aagatagata tgaaacagca gcaaagatag ctgataaaca
    22261 gacttatgaa acagtaattt tagtaaatac agaaaaatca cttgcagatg gattaagtgc
    22321 aagtggatta tcgggaacta caaaagctcc aatactattt acacaacaaa ataagatacc
    22381 agcagacaca aatagatgtc taaaaaatat caaaaaagca tatataatag gtacagaaga
    22441 tactataagt aaatcagtag aaaaagaact agattctaaa aatatagaag tcaaaagaat
    22501 tggtggagaa gatagactaa aaacaagcta tttaatagct aaagaaatag caactataaa
    22561 aaaagtggat aaagtactat taactaatgc atatagtgga gaagcagacg caatgagtgt
    22621 atcatcagta gctactagag atggagctcc aatcatactt acagatggaa agagtgtgcc
    22681 ttttgatgta aaaaatattc aatcatattg tataggttca gaggagataa tgagtaatcc
    22741 tctagttaaa aatacaaact cagtaagaat agaaggaact gaccgatttg aaactaacaa
    22801 aaacgtaata gactactttt ttaatagtgc agatggattc tatgtatcag atggatacca
    22861 attagtagat gcaatagcag ctgcaccact tactaaaaac tctccaatgg tactagtaaa
    22921 tgatggaagc gataagactg tattagaagg agctaagaat ataacctctg taggtgaaat
    22981 agatgagaag gtaatacaac aatgtataag tgcttcaaag tcaaatggac aacccccaac
    23041 aattacagtt gggagtacag agatatataa gggtgaaaag tttgacactg gcaagttaaa
    23101 tatagtagct aaagataaca ctgggaaggt attaccaata gaagttgatg ggtttataga
    23161 tacaaataga gtaggtacat atatattgac attaaaagct acagacgaat ggggagaaag
    23221 tacagaaaaa agagtagaaa taaaagtgtt ggatgataaa tctcatgatt ataacagccc
    23281 agaatttaaa aaaatggtat ctactgaaat gtataactta atcaattcct atagaaaaga
    23341 aaaaggcaaa gagcctttgg tagtatctag taggctagaa ggtatggcaa attcatggtc
    23401 taagtatatg atggataaaa aagtatttgc acattatata gatggaaaaa atgctccaca
    23461 agtattttct gagtttggaa tgagaagtga ggaaaatata gcatatattt atatagattc
    23521 taagaacgtt caaactacac aagatgcaaa agacttggca aaggctatat ttgaggtgtg
    23581 gaagaagtct ccagagtaca atgcaaatat gcttagtgat gagttctata gtactggatt
    23641 tgggctttat atattatctg atggtcaagt gcatgctact caggagtttt taaatggaaa
    23701 tgaaggtagc ttgtaaaaaa ttccacaaat cttgtttttt tgttaattta ctgatattat
    23761 aaaatgaaaa tcacatctaa agtacttttt gtaatctgtt ttgttattgt tttacaggtt
    23821 atggtatttt aggtgttttt tgttttagta gtttataaat tttgagggaa tcactactga
    23881 ggatgtaatt tatgattagc tgaattatat aaaaaaatta gtaggaggag ttcgatgaag
    23941 gtaaataaga gagtattatc aataggattg acaatatcat taataatggc aggagcacca
    24001 aatatcaatg cactttcaag tatagaaaag atacaaggga aagatagata tgagacttct
    24061 gcattgatag cagataaaca aatatatgat acagtcatat tagtaaatac tgataattct
    24121 atagtagatg gattaagtgc aagtggatta tctggagttg taaaagctcc tataatgtta
    24181 gtgcaaagag ataagatacc aacagatgtt gaaaaaagac taaaggatgt taagaatgct
    24241 tatgttatag gtacagagga tacaataggt aaatctgtag aaaatcaact taagaataaa
    24301 gggattgaag ttaaaagaat tggtggggaa gatagaataa agactagcta tcttatagct
    24361 aaggagattt cagctattaa accagtaaat gatggtgata aggtttttct tgtaaatgga
    24421 tacacaggtg aggctgatgc aatgagtgta tcttctgtag ctgctagaga tggagttcct
    24481 gttatactta ctgatggaaa gagtatacca tttaaggttg atggcgttca atgttattct
    24541 cttgggtcag aggagataat gagtaatgaa cttgtgagta agactaattc tgttaggatt
    24601 gctggtaagg ataggtttga gactaataag aaggttatac aacgctttta taaaggaaca
    24661 aagaagtttt atgtttctca agggtataag ttagttgatg ctgtggttgg ttctccgttg
    24721 gctaaggaca aacctatagt acttgttaat gatggaagtg ataagagtgt gcttagaggt
    24781 gctgatgaag ttacttcttt aggtggaatg gataagaagg ttgctgacca atgtattagt
    24841 tctgcatctg ataaaaatac aatgcctaca atcactgcta atgatgtaga gatttctgta
    24901 ggggataagt ttgataatag tatgttgaat atagttgcta ctgattatta tggaaataat
    24961 ttgaggccta atattgaggg aactgtggat accagtaagg cgggaacgta tgttttaaat
    25021 gtaagtgctt ttgataattt tgggcaaaag tgtgagatta atgtaaatgt caaagtaatt
    25081 gtaaatacaa gtacaaaaga ccctaatagt tatgagttta aggctatggt atctaatgaa
    25141 atgtacaatc tagttaattc atataggaaa gaaaaaggta agagagcttt aagagaatta
    25201 gattctctag caggaatggc aaatgcatgg tctaagtata tggatgagaa gaaggtattt
    25261 gcccatgaga ttgatgggaa aaatgcagct gaagtatttt ttggatttgg agcaagaagt
    25321 ggtgaaaata ttgcatattt acctatgaat gttaagtctg tttataacgc taaagatgca
    25381 aaggatattg ctaagtctat ttttgattta tggaagaagt cttctaagta taatgagaat
    25441 atgttgaaag aagaatttta tagcttcggg tttggtatgc atatttctag taaaggagaa
    25501 gtgaatgcaa caatggaatt tttaaatagt tagattttat attaattcat attaaaaaag
    25561 atatagcaaa tttgtaaaaa ataggtgcat aaaattaaaa aaactttaaa attataaaaa
    25621 ataatttaaa atgcataaaa atgatgaaaa agcaattaaa ttgttggaaa aaacttcgat
    25681 taattttgca taagtcattg aaattatatc ttatatagtc tatcataaga gtgtgagaaa
    25741 tatttggacc atatgaacat gaaatttata tgtacataat taaagagatg taatttaata
    25801 taatgttggg aggaatttaa ggaatgaata agaaaaattt agcaatggca atggctgctg
    25861 ttacagtagt aggttcggct gcaccagtat ttgctgcaac tactcctagt gaggacaatg
    25921 caggtaaata tactgtagta aaggataaat acaaagatat atttgatgaa gtaaaaaaac
    25981 tagttaaaga aaatgatgca gctatagatg catatttaaa agaaaataac tctactgata
    26041 gagacgcagc atggactgca ctagcgggaa ctaattcact taatataata aatataacag
    26101 tgaaagattc tgatgatgat tcagtagtag ttccaaaaac tgtagtaaaa acaaatactg
    26161 ttgttgatac agattatgtt gaaaataagt tgaaaaattt agatacagat gaatatgtag
    26221 attttgatat aactacaaaa gctagtactg tttcatctac aaaatataca gcagctaata
    26281 tatatgattt agcagctaat aatggtaaga taataattga tgcattaaaa aatgttacag
    26341 aaaaacaact taaagatggt ggtatcttag gggaagtagc aaaaactatt agtggtgcaa
    26401 ctacaccaag tgcaccaaca ggcgatacat ttgcatctta ctttacggtt ggaacagtta
    26461 agactgtaaa tggtaaagtt gctcttgaaa taaacatagc agaaccagca tcaactgtat
    26521 tagttaagac tgatgcagaa ttaacaactt cgccaacaac tcaacaaaaa atgagttttg
    26581 ctaatgctaa aattacttta actgaaggtg atgacagatt agatttctct aaaccttcta
    26641 tagtagatgg agctttaggt gattttgcta aagcagcagc tacaacaact ccaggaaaac
    26701 aacaaactat aaatgttaga gtaataaatg ctaaacaaga aactgtaaaa gcaacagact
    26761 atgatgcttt aaaagcggtt gtgtcaaaat acaagtttga ctctactgaa ataggaagag
    26821 tatatgatga agcaaaggat ttaaatgata aagataagct tgatggtagt tcatatgata
    26881 aagatggtac ttataaagca gttttctttg ctgaaggaaa aagattacaa ggattttcat
    26941 cttatggaaa attctcaact gatgaagctg aatctggttt agccgatgga aatgcagctc
    27001 ttaaattagt tatagagtca actgatgaag atgattttat agatggatta aaggacttaa
    27061 aagagttaaa taatagttac tcagatgttg aatctgttgc aggtgatgac agaatagaaa
    27121 cagctataga gttaagtaag tcgtattata ataatagtag aagtaataat tctgatactt
    27181 tatatacagg tgcagtagat aatgttgttc ttgtaggttc acaagctatt gtggatggat
    27241 tagtagcagg acctttagca gctgaaaagg aaggaccatt attattatct tcaaaagata
    27301 aattagataa taatgttaaa aatgaaatta agagagttat gggattaagt agcactaatt
    27361 ctatagattc taaaaagaaa gtttatatag ttggtggaga aaattcagtt tctaaggatg
    27421 ttcaaaaagc aattgaagat atgggagtaa aagttgaaag attatctgga gatgatagat
    27481 atgcaacttc tcttaaaata gccgataaag ttgaattaaa tgataaagat aaagcatttg
    27541 ttgttggtgg aacaggacta gcagatgcta tgagtatagc accagttgct tctcaattag
    27601 ttggaaaaga agctacacca atagtagtag tagatggaaa agctgataaa ttatcttcag
    27661 atgcatcaga tttcttagat tctgcaaaag aagtagatat aattggtgga gaaaattcag
    27721 tttctaataa agtgaaagat tctataaaag atgctatagg aagatctgta gatagaataa
    27781 gtggagatga tagacaagct actaatgcag aagttataaa agaatattat gaaaatgatc
    27841 ctaagaatgt taaaaatata tttgtagcaa aagatggctc aactaaggaa gatcaattag
    27901 ttgatgcatt agctgcaggt gcaatcgcag gaaatcttgg attatcagct ggtgaggatg
    27961 aagtttctcc agctccaata gtattagcta cagataactt atcttctgaa caacatgttg
    28021 ctataagtaa agttgttaat gataaacaaa ctaacaaaat agttaaagtt ggtggaggca
    28081 tagctgattc agttattaat aaattaaaag atttattagg aatgtaatag tataatttgt
    28141 gaattaaatt aaagagactt ctcatagaga ggtctctttt ttatgaaatt ttataaaata
    28201 aaaagaagca gtttaatttt aaatagtatt aatcaaaatt aaactgctct ttttgtgaga
    28261 aatactcaaa taaaaagatg taactattta tttaagtatg attattatac tatacattaa
    28321 aaaaattgtc tactattcta aatttttaat gtataatagt aagagaaaca taaattagga
    28381 ggtaaaataa atatgtcagt tttagatatg atattagaca aaacagatga aatagaaatt
    28441 aaaaaattaa ataatatagt agataagata gatgcattag aaaataaaat acaattatta
    28501 agtaatgatg agttaaaaaa tatgacaggt atatttaaga gtaggttaaa taagggtgaa
    28561 actttagatg atattttgcc agaagccttt gctgtagtga gagaagtatc gaagcgaata
    28621 ttaggtatgc gtcaatatag agttcaatta attggtggaa tagtgttgca ccaaggtaaa
    28681 atagctgaaa tgagaactgg agaaggaaaa acattagttg gagtagctcc cgtttattta
    28741 aatgcattag aaggaaaagg ggtacatgta atcacagtta atgattattt ggctcaacgt
    28801 gataaagaac taatgaaacc agtatatgag tttcttggaa tgaaagttgg agtaataatt
    28861 aatggacaac aaccatcaga aagaaaatta caatatcaat gtgatattac ctatggtaca
    28921 aataatgaat atggatttga ttatttaaga gacaatatgg tgacaaagaa aatagataag
    28981 gttcagagag aattgaattt tgctatagtg gatgaagttg actctattct tatagatgaa
    29041 gctagaactc ctcttataat tgctggaagt ggagaagaag gaactaaact ttacgaactt
    29101 gcaaatgcat ttataaaaac tataaatgat gaagattttg aaatggatag aaaagataaa
    29161 acaatagcgc ttacacaaag tggccttagt aaagcagagt cattttttgg tatagaaaat
    29221 attacacata ttgataatat agaaatattt caccatgtta atcaatctct tagagctcat
    29281 aaactaatga gtatagatgt tgagtatgtt gttaaagaag atgagatact aattgttgat
    29341 gaatttacag gaagaataat ggatggtaga agatttactg atggtcttca tcaagctata
    29401 gaagcaaaag aaggtgtaaa gataaaagat gaatcaaaaa caatggcaac tgttactttc
    29461 cagaatttct ttagactata ttctaaatta tctgggatga caggtactgc aaaaactgaa
    29521 gagagcgaat ttgagtctac atataaaata aatgttgttc aaataccaac taataagcca
    29581 gttataagag ctgatttaca tgacaaggta tttaaaacag aaaatgctaa atataatgca
    29641 gttgtagaag aaataataag aataaataaa actaaacaac cagttcttgt tggaactgtt
    29701 tccattgaaa aatcagaaaa gttgtctaga ttgttgaaaa agagaggaat taagcatcaa
    29761 gttttaaatg caaaacagca tgataaggaa gctgaaataa tatctaaagc tggtaaatta
    29821 ggttctgtaa caattgctac aaatatggca ggtagaggaa ctgatatatc tcttggtgca
    29881 ggagatgaag aagaagagaa gatagtaaaa gatttaggag gattatacgt tataggaaca
    29941 gaaagacatg agactagaag aatagataat cagcttagag gtcgttctgg tagacaagga
    30001 gatccaggaa cttcaaggtt ttttgtaagt ttagaagatg aagtaataaa attatatggt
    30061 ggtaaaacaa tagaaaaaat attaaaaaga atgagtacaa aagaagaaga agctctagag
    30121 agtaaagccc taaatagagc aattgaaaga gctcaaaaag gtattgaagg gaaaaacttc
    30181 gaacaaagaa agaatgttct taaatatgat gatactatta atgagcagag aaaagttatc
    30241 tacaatgaga gaaataaagt tttagatgat ttaaatattt ctgatgagat acaaaaaatg
    30301 gtaatagaga ttatccaaga gtctgctgat aaatatttga aaaagactag agattatcaa
    30361 ggttatttta gatacttata taaaatattt atgccagctg atacattatt aattccaagg
    30421 ctagatgaaa aaagtgttga tgaaataatt aatcaaacat atgaaatttc taagagagta
    30481 tatgatctta aaaaaatgat gattggaatt aaagagctag aaaaattgga gagaaaagta
    30541 ttacttgagg ttgtagatac ttattgggtt gaacatatag atgctatgga tcagttaaga
    30601 caatatatag gtcttaaagc atatggtcag aaagatccat ttaaagaata tgcaatagaa
    30661 ggatatgaaa tgtttgaagc cttaaacaaa aatattagag tgtcaacagt tcaatacctt
    30721 tataaatttg aataacataa tgaagttgta tgatatgaat gaaaacatac ttttaagagc
    30781 ttaatttaaa tgaaaaagag gctgaaaatc agcctctttt tctgtgtgag aaatacggaa
    30841 aaaagagatg cttgaaattt ctttcttcca tttaatatta tactataaag aagatgaaaa
    30901 gtctattagt tataaactgg attattaaaa aaaattacaa ttttgttact tttttgtata
    30961 cataaatatt aaaaaataaa atatcagaaa aggtttatat cttttggtta attattacaa
    31021 taagtctcat ttattgaaat aatatcaaat atatattata attggtaaat aaggaaaaaa
    31081 taataaaaat ttgaattttt tagggggaaa ataccatgaa taaaaaaaat ctttctgtaa
    31141 ttatggctgc tgcaatgata agtacatcag tagctccagt ttttgctgca gaaactacac
    31201 aggtaaaaaa agaaacaata actaagaaag aagctacaga actagtttcg aaggttagag
    31261 atttaatgtc tcaaaagtat acaggaggtt ctcaagttgg acaaccaata tatgaaataa
    31321 aagttggtga gactttatca aaattaaaaa taataactaa tatagatgaa ttagagaaat
    31381 tagtaaatgc tttgggagaa aataaagaac ttattgtaac tataacagat aaagggcata
    31441 taacaaatag tgcaaatgaa gtagttgcag aagcaactga aaaatatgaa aattcagcag
    31501 acctttccgc tgaggctaat tctataacag aaaaagctaa aactgaaacc aatggaattt
    31561 ataaagttgc agatgtaaaa gcttcatatg atagtgctaa agataagtta gttataactt
    31621 taagagataa aacagacaca gtaacttcta aaactataga gataggtatt ggtgatgaaa
    31681 aaattgattt aacagcaaat ccagttgatt caactggaac aaacttagac ccttctacag
    31741 aaggatttag agtaaataaa atcgataaac taggtgtagc aggagctaaa aatattgatg
    31801 atgtccaatt agctgaaata actataaaaa atagtgacct aaatacagtt tcaccacaag
    31861 atttatatga tggatataga ttaactgtta aaggtaatat ggtagcaaat ggaacatcaa
    31921 agtcaattag tgatatttca tcaaaagatt cagaaacagg aaagtataaa tttactatta
    31981 agtatactga tgcatctgga aaagcaatag agcttactgt agaaagtact aatgaaaaag
    32041 atttaaaaaa tgctaaagct gcattagaag gtaattcaaa agttaaatta atagctggag
    32101 atgatagata cgcaactgca gtcgctatag caaaacaaac aaaatatact gacaatgtag
    32161 ttatagttaa ttcaaataaa ttagttgacg gattagcagc tacaccactt gcccaatcta
    32221 aaaaagcacc tatattgtta gcatctgata atgaaatacc aaaagtaact ttagattata
    32281 taaaagatat aattaagaaa agcccatcag ctaaaatata tatagtaggt ggagaatcag
    32341 cagtatcaaa tacagctaaa aagcaattag aatcagtaac taagaatgtt gaaagactag
    32401 ctggagatga tagacatatg acttctgtag cagtagcaaa agctatgggg tcttttaaag
    32461 atgcatttgt agtaggcgca aaaggggagg ctgatgctat gagtatagct gctaaagctg
    32521 ctgaacttaa ggctcctata atagtaaatg gttggaatga tctatcagca gatgctatca
    32581 aattgatgga tggaaaagag attggcatag ttggtggttc taacaatgta tctagtcaaa
    32641 ttgaaaatca acttgccgat attgataaag atagaaaagt tcaaagagtt gaaggagaaa
    32701 caagacatga taccaatgct aaggttatag aaacatatta tggcaaatta gataaactat
    32761 atatagcaaa agatggatat ggaaataatg gtatgctagt agatgcattg gcagcaggac
    32821 ctctagcagc aggtaaaggt ccaatacttt tagctaaaac tgatataaca gactcacaaa
    32881 agaatgcgct tagtaaaaaa ttaaatcttg gtgcagaagt aactcaaata ggtaatggag
    32941 ttgaattgac agtaatacaa aagatagcta aaatactagg ttggtaataa cttatactgt
    33001 ggagaagatt ccttaattaa tacaggaatc tttttctata attatgctat ttattgtaaa
    33061 ttataacatt ttatgaagta ggaggatgta gtagtggtag atgcaacttt attttttaca
    33121 ccacatcaag atgatgaaac cttaagtatg ggaagtgcta taattgaaca tgttgaaaaa
    33181 agtgatacac atgtcatatt atgcacagat ggcagtaaat ctataataag aaaagttttg
    33241 gatgatggag ggtcatgttc ttatcatatt aaagatgttc ataaatattc tttatcagaa
    33301 agtgagtttt caaaagatag agatgaagaa tttaaggata gttgtaaagc aatgggagta
    33361 aaatctagta atatacatat agaagaaaat agagctcatg atggtgagtt aagtaaagaa
    33421 aaagcaagag aaataatact taagtactta gaagaatatc caaatgcaag agtaaaaact
    33481 gttacccctt acaaagctag tggaatacat gaagatcata gagcattagg agaagcagcg
    33541 ttagaactat atgaagaagg taaaataaaa gatttaagat tttatgtgga accttatgat
    33601 tatattgatt ttaaaaaagt taacccaaat gtaaaggtgt gggaggtatt aactactcaa
    33661 gaggagaaat tattaagtgc aatgaatgca tataaaaagt ggcatccaga aagcggacat
    33721 tatgcaattg gatatcattc tgtaaaatca cattttgagg agttaaaatc taataaaatt
    33781 cagtatgttc atgccccata aaagtttatc ttagaattag gaggaaataa tcaatgaaag
    33841 cttcgaaaaa agtaatgctt ttattaacaa tatcatttat atcaacttgt ttatatacaa
    33901 ataaagtcag tgcagctaca aaagatactt tagtaggttc aggaagatgg gaaacagcta
    33961 taaagataag tcaaaaagga tggtcaagta gtactaatgc tgttttggta aatgataatt
    34021 caatatcaga tgcattatct tcaactccat ttgcaagagt gaaagatgct cctattttac
    34081 ttactcaaaa ggataaatta gataatagga caaagctaga attaaagaga ctaggtgtaa
    34141 aaaatgtata tttaattggg ggaattaatg cattaagtca agatattgag aaagaattaa
    34201 aattagaagg aataagcttt gagagaatat cagggaatga caggtatgat acatctgtaa
    34261 aattagctga aaaattagac aaagaaaaaa aattttctag tgtatttgta gttagtggta
    34321 aaagtggatt agcagatgca gtaagtatag ggtcaatagc agctcaagaa ggtatgccaa
    34381 ttatactttc aaacccggaa aatggaataa aattagctga taaacttatc aaagaaaaaa
    34441 atataaataa atcatacata ataggaggta aactttcagt ttctgaatct gtagaacaaa
    34501 atttaccaaa tgttaagaga atttcaggta ataataggaa cgaaactaat gcaaaagtta
    34561 tagaagaatt ttataagtct acaaatctaa aaaatgcata cataactaaa gatggaatga
    34621 gaaatcaaag tgatttaatt gattctttag cagtaggagt attagcatca aaaaacagtt
    34681 ctccagttgt attagtagga aaagaacttg attctgctca aaaagatatc atgaatacaa
    34741 agatatttga taaaataact caagttggtg gattgggtaa tgaaagtgct acaaaaagca
    34801 tagctgatat gcaagaacaa actaagtata ctgttgaatc aattgaagaa ctaaatgttg
    34861 cattaaaaaa agcagatgct aacgatgtaa ttaaatttaa agcagaaaaa gataagaaag
    34921 taacagattc atttaaattg gaaactaaaa aagctataac tatcgaattt gatgggacat
    34981 atactcaaac aataaccata gatatgccaa atggagatat aaataatttt ggtaaaatag
    35041 atggaagttt tataattaat aatataaaga ataatacatt agtaaataaa ggtgatataa
    35101 atcaaataga tgtttattct aaaaatggat gtaggataga aaatcaaagt tctggagata
    35161 tatggcttat aacaatactt aaagaggcaa aaaatgtata tatagaaaat gatggagata
    35221 taataaaaat atctaatagt tcaaatgatg ttacactaaa aaattatgga agtgttgata
    35281 agataagtgg aaataaagaa ttagctataa ttgggaataa acctaggatt aatgatacta
    35341 tagaggatga taaagagaaa gctagtgaat tatatccaga agtaaaatca tgtacacctg
    35401 ctcaaagtaa ctttataatg ctacatattt ctcaagaacc taagtactca gattatgcaa
    35461 tatactatag agtagtaaaa agtaaaccat cagcaattaa aataggagat aagattgaca
    35521 tagatgactg ggatattgta aaaggaacaa ctccttttaa agtaaatgct ataaatggat
    35581 cttatataga atgtgttgaa atagataaat caaacaaaag tgttagaaga tggggacgaa
    35641 caggtgaaac aaatgatggt gtaaaggttg aagaagttgc aaatggtcta gatgtagatg
    35701 taaatataat tggtgaaaat gtgaagataa ctactccaaa agctaatctt gactgcaaaa
    35761 tttattatag aatttctgaa attaaaccaa cagcaatgaa tgttggagaa aaaattaatt
    35821 tatctagttg ggatagtgtc ataggtaact atgtagaatt aagatttaat gatgtaaaag
    35881 gaaagtatat agagttagta gaattagata attcaaataa tttagtaact agatggggta
    35941 aaactgataa gatagttgtg acaagttcag aaatataaca aacaagaaga atgtctattg
    36001 tttataaata ataagtgtat ataatagaca tcttaaaagt taccttataa gcagtatact
    36061 atatagtata ctgcttatta atttatattg tcttttttaa aaattatcat tttactaaac
    36121 aaataattta aaactataac aactatatta gtaaatactt ttacaatgat atcatttaca
    36181 aaaagcaaat caatcattac atacataatt aacatttcaa cgacaccaga aagtagccta
    36241 aaactaacaa aagacaaaaa ttctttaaat acgaacctta tttcaattct tttactttca
    36301 aacacaaaaa acttattagt aacataagca aataaaacag caagtatcca tgccaaagaa
    36361 tttgcaagca taaaattaaa taaaataact ctagtaaaaa ataaatacga aactatattt
    36421 acaagagtag taaatgctcc aaaaaataaa tataatattg tctctctatg tttttttaaa
    36481 atcaaatata atcctcctaa gctaatttaa tataaatata cttaaagata ctaacaaaca
    36541 ttagtatagc acatctatta ataaatcaat atatcttaaa atattataaa aataaaacta
    36601 taatattcta taattaatat gtactcataa tccatatttt atcaaaataa aatatgacct
    36661 taatttagaa atctgatata ataaaaatta aatacatata agggggtaaa catgagaaag
    36721 tacaaatcaa aaaaattgtc aaagctgcta gcattgttga cagtttgctt tttaatagtg
    36781 tcaacaatac ctgtctcagc agaaaaacat aaaactctag atggagtaga aactgcagag
    36841 tattctgaaa gctatcttca atacctagaa gatgtcaaaa atggagacac agcaaaatat
    36901 aatggagtaa taccttttcc acatgaaatg gaaggtacaa cacttcgaaa taagggtaga
    36961 agtagtcttc catcagcata taaatcaagt gtagcataca atccaatgaa tcttggtctt
    37021 actacaccag caaaaaatca aggaagtctt aatacatgct ggtctttttc agggatgtca
    37081 actttagaag catatcttaa attaaaagga tatggaacgt atgacttatc agaagaacat
    37141 ttaagatggt gggcaactgg tggaaaatat gggtggaact tagatgatat gtcagggagt
    37201 tcaaatgtaa cagctatagg gtatctgaca tcatgggcag gtcctaagtt agaaaaagac
    37261 ataccatata atcttaaatc tgaggcacaa ggtgcaacta aaccttcaaa tatggatact
    37321 gcacctactc aatttaatgt aacagatgtt gttcgtctta ataaagataa ggaaactgta
    37381 aaaaatgcta taatgcaata tggttcagtg acatcaggtt atgcacatta ttcaacatat
    37441 tttaataaag atgaaacagc atataactgt acatataaga gagctacatt aaatcatgct
    37501 gtagcgatag taggatggga tgataattat tcaaaagata actttgcatc tgatgcaaaa
    37561 ccagaatcaa atggagcatg gttagtaaaa agtagttggg gagagtttaa ttctatgaaa
    37621 ggattcttct ggatttctta tgaagataaa actctactaa cagatacaga taactatgca
    37681 atgaaatcag tatcaaaacc agatagtgat aaaaaaatgt accaacttga atatgctggt
    37741 cttagcaaga taatgtcaaa taaagtaacc gcagcaaatg tatttgattt tagcagagac
    37801 tctgaaaaac ttgactctgt tatgtttgaa acagactctg taggagcaaa atatgaagta
    37861 tattatgcac cagtagtaaa tggagttcct caaaacaatt caatgacaaa acttgcaagt
    37921 ggaacagtat catattctgg atacataaat gtacctacta attcttatag cttaccaaaa
    37981 ggtaaaggag caatagtagt agttatagat aacacagcaa atcctaatag agaaaaatca
    38041 actttagcat atgaaactga tatagatgga tactatctat atgaggctaa agcaaactta
    38101 ggtgaaagct atatacttca aaataataaa tttgaggata taaatacata tagtgaattt
    38161 tctccttgta actttgttat aaaagctata acaaaaacat cttctggaca agctacttca
    38221 ggagaatctt taacaggagc agatagatat gaaacagcag ttaaagttag tcaaaaagga
    38281 tggacttctt cacaaaatgc agtattagta aatggagacg caatagtgga tgctttaaca
    38341 gctacaccat ttacagcagc aatcgactct ccaattcttt tgacaggaaa agataactta
    38401 gattcaaaaa ctaaggcaga gttacaaaga ttaggaacta aaaaagttta tctaataggt
    38461 ggagaatact ctttaagcaa gaatgtacaa actcaactta gcaatatggg tatatcagta
    38521 gaaagaattt caggtagtga tagatacaag actagtatat ctctagctca aaagttaaat
    38581 agtataaaat ctgtttcaca agttgcagtg gcaaatggtg taaatggact tgcagatgca
    38641 ataagtattg gtgcagtggc tgctgacaat aatatgccaa taatacttac taatgaaaag
    38701 agtgagttgc aaggtgctga tgagttttta aagtcatcta aaataactaa gtcttatata
    38761 attggtggaa cagctacttt atcatcaaat ttagaaagta agctttcaaa tccaacaaga
    38821 cttgcaggaa gtaatagaaa tgaaactaat gctaagataa tagataaatt ctaccctagc
    38881 tcagatttga aatatgcttt tgttgttaaa gatggttcaa agagtcaagg agacttgata
    38941 gatggactag cagtaggagc attaggtgct aaaactgatt caccagtagt tatagttgga
    39001 aataagttag atgaaagtca aaaaaatgta cttaagtcta agaaaataga aactcctatt
    39061 agagttggtg gaaatggaaa tgaaagtgct tttaatgaac taaatactct tttaggaaaa
    39121 tagtgaatgg aaagatagta aggatataca ttttagtatt aaaaaatatt caatagaagt
    39181 ttataaatat aaaataacaa aatggggtgt ctcaaaatga actttttagt tcatgaggca
    39241 ctctttttgt attaaatcaa atatattttc atcatttcaa cgattaagaa taggcttgtt
    39301 tatattttta gatagttttc ttattattga tgaaaaatgt aataatttta aactgtaaaa
    39361 tagtgtaaag ttattttata atataaatat agtaagattt taaacaaaat aaggggggaa
    39421 taataatgaa agcaccaaaa actattttaa caatactaac aatagcgctt actttaagta
    39481 gcatttctat aataccatca tatgcactta cagaggaaaa attaataggt aatggtagat
    39541 atgaaactgc tgtaaagata agtcaaaagg catacagttc tagttctaat gtagtgttag
    39601 ttaatgacaa ttcattagct gatgcacttt cagccacacc atttgcaaag gctaaaggag
    39661 caccaatact tttgacagaa agtgataagc tagatgatag gactgaaaaa gagataaaac
    39721 gtctaggagc taaagatatt tatttgatag gaggtactgc tgtacttaat aaagatatag
    39781 agaacaagtt aaaaagtaat ggacttaatg tagaaagaat taatggtaag gatagatatg
    39841 aaacttcact gattttggct aataagctta aggatataaa agatattaag gaagttgctg
    39901 tagtaaatgg tgaaaaagga ttgagtgatg ctgttagcgt tggggcacca gcagctcaaa
    39961 ataagatgcc tataattttg tctagtccta aggacggagt agaagcattt gataaattta
    40021 taagggatga gaaagttata aaagcatatg taattggagg tacgacttca gtttcaagag
    40081 ctgtagaaaa gagtcttcct aatgcagaaa gagtgagtgg gaaagataga aatgagacta
    40141 atgctaaagt tatagaaaag ttttacactg atacaaattt aagtaattta tatgtaacta
    40201 aggatggtag taaaaatgag aatcaactaa tagactcgtt agctgttgga gtattggctg
    40261 caaaaaatga gtctcctgtt gttttggttg gtaataaatt aaacacaaaa caaagagata
    40321 tacttagtac taaaaaatta aatactataa cacaggtagg tggaaatgga aatgaagaag
    40381 cttttgatga aattaaaagt ctacaagaaa aaactgtgtt tgaagcaaaa actgttgagg
    40441 aattaactga tatgataaat atagcaagtc ctaatgatat tataaacttt aaaccaaaag
    40501 aaaatactgt aaatgaagct tttagaatgg taacaaataa accaataact gtgaatataa
    40561 agggtgattg ttcaaagact cttacagtag atatgcctaa tggtgaagtg aataactatg
    40621 ctactttggt aaatgttata gttagaaata ttggagaagg tggatttaat aaccatgata
    40681 caatcactat attgtcagtt cgtgacaaaa atggtagagt tatagaaaat actagaaatt
    40741 cagatataga tacgttgatg atattagctt ctgctaatga tacaaaattg attaatgatg
    40801 gatatatagg aaaacttata gataattcat ctaatagtga tataactaat aatggtacta
    40861 tagataaaaa agttaatcag gttgaagatt tagaggctaa agtagattca attgaaaaag
    40921 ctatagattc tataagtcaa aaagtcaata aaatacaaga tatactagat aagcttggat
    40981 ttctaaagaa atttcttagc taagaatatg tatatttaag tgaagtgtgt gttgtaattg
    41041 ttctaaattt atgtagttaa acaggtttat atacaaatag atttatagat aaatatgtag
    41101 tttagtatat atttgaataa gctttgggga ggtaacatgg ggattggaat tgaatgtaac
    41161 aaaaaaataa ataaaagtat tgacaaaact agaataaaga aaaataatct
//
LOCUS       DAEORM030000034        39544 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.034, whole genome shotgun sequence.
ACCESSION   DAEORM030000034 DAEORM030000000
VERSION     DAEORM030000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 39544)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39544)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 39544)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39544
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.034"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            <1..1144
                     /locus_tag="KRH23_002285"
     CDS             <1..1144
                     /locus_tag="KRH23_002285"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HHS5225563.1"
                     /translation="ISNNAVDSKLTNSRIKSIDIIRGLSIALMIVCNNPGTWMRMYPQ
                     LRHAVWHGVTLADFAFPFFVISLGVTIPISINSKLKNNKSTLSIILSIFKRSILLILF
                     GFFLNYLGNPDLDTVRILGVLQRMGLVYFVTSLVYLLLKKLNVGSTATIITFLCISTF
                     IIVGYYILAKPYGFELEGSLAQLVDLHFFKGHLYKPEFEPDGFLTSIVAISSGMLGCT
                     MGCVLLKENLGEYKKFFKILVMSIILLICAFIFNQYFPFNKRLWSSSFVLLMAGSYGI
                     LLSIFYFICDIKNKSKIFTPIIALGSSPIFTYMCLEILSHVFWNVPKLTNKVDYPTTL
                     VEWTTYELITPWAGTTWDSLIFSLLYVLFWVIVMSIMYKKKIFIKI"
     gene            1398..3422
                     /locus_tag="KRH23_002286"
     CDS             1398..3422
                     /locus_tag="KRH23_002286"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008745 - N-acetylmuramoyl-L-alanine
                     amidase activity [Evidence IEA];
                     GO_process: GO:0009253 - peptidoglycan catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HHS5225564.1"
                     /translation="MKKTTKLLATGMLSVAMVAPNVALAAENTTANTESNSDININLQ
                     RKSVVLGSKSNASVKFKEKLNADSITLNFMCYDMPLEATLNYNEKTDSYEGVINYNKD
                     PEYLNVWELQSIKINGKDEQKVLNKEDLESMGLNLKDYDVTQEFIISDANSTKAVNEY
                     MRKTSAPVKKLAGATRFETAVEISKQGWKDGSSKVVIVNGELAADGITATPLASTYDA
                     PILLANKDDIPESTKAELKRLNPSDVIIIGDDGSVSQKAVSQIKSAVNVNVTRIGGVD
                     RHETSLLIAKEIDKYHDVNKIYIANGYAGEYDALNISSKAGEDQQPIILANKDSVPQG
                     TYNWLSSQGLEEAYYIGGSQSLSSKIIDQISKIAKNGTSKNRVSGADRHETNANVIKT
                     FYPDKELSAMLVAKSDIIVDSITAGPLAAKLKAPILITPKTYVSAYHSTNLSEKTAET
                     VYQIGDGMKDSVINSIASSLSKHNAPTEPDNSGSAAGKTVVIDPGHGGSDSGATSGLN
                     GGAQEKKYTLNTALATTEYLRSKGINVVMTRDTDKTMALGERTALSNTIKPDLFTSIH
                     YNASNGAGNGVEIYYKVKDKNGGTTKTAASNILKRILEKFNMKNRGIKTRTLDNGKDY
                     LYVLRNNNYPAILVECAFIDNKSDMDKLNTAEKVKTMGTQIGIGIEDTVK"
     gene            3642..4328
                     /locus_tag="KRH23_002287"
     CDS             3642..4328
                     /locus_tag="KRH23_002287"
                     /EC_number="2.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA];
                     GO_process: GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HHS5225565.1"
                     /translation="MSGYTNDECEIPKIKSYPGADKEIASEIDYSIVKGTVLFDLYQR
                     IMDLVLSIIGLVIGLPLIAIFGILIKIEDKGPITYKQERLGKCGRRFYIYKLRSMRTD
                     AEKFGAQWAEKDDPRITKVGKFIRKTRIDEIPQLFNILKGDMGLIGPRPERPNFTVQF
                     NEEIPGFINRLAIKPGLTGWAQVNGGYEITPEEKLKEDIYYIKNRSILLDFKILFKTV
                     KVVLTGDGAR"
     gene            4423..5478
                     /locus_tag="KRH23_002288"
     CDS             4423..5478
                     /locus_tag="KRH23_002288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp7"
                     /protein_id="HHS5225566.1"
                     /translation="MIKKISTILSLVLLISISSTIGVFADANPKRELIEGSIPEISTE
                     LNKRAFKDSKEVILVNEESIVDSISATPLAYAKNAPIVVTKSKNLGRVTRNYLKELGP
                     EKVTIVGGLKAVSKDAERNIEKMGMKVERIRGKDRYDTSLKIAREMYRTVGFDEAFLL
                     SSTTGLENAISVYSYAAKSGMPIIWAKDEGFEEQIDFLKGKNLKKIYALGDSKEFIAE
                     IDSNLKNIEGIKQINKSSTNVDLIKKFYDEKDIKKIYTARLDFGSRSDVNEYISLGVV
                     SAKENMPILICSDNLSRAQDKFLKDSNINDVVEVGYTVGDYSLFKSIFNLTFLSCIVL
                     ILLLLLITFRALRYESK"
     gene            5593..7149
                     /gene="murJ"
                     /locus_tag="KRH23_002289"
     CDS             5593..7149
                     /gene="murJ"
                     /locus_tag="KRH23_002289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0034204 - lipid translocation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="murein biosynthesis integral membrane protein
                     MurJ"
                     /protein_id="HHS5225567.1"
                     /translation="MSKTAKAALWIMAATMFSKVLGFLRELVLANFYGTGMYADVFVL
                     TLNIPGLIIAVIGSAVATTYIPMYFETKKRLGDEGALKFTNNVLNICYIMAIVIAIIG
                     LLFTEQFVTVFAAGFRNDPAKFQAAILFTKIMISGVLFLSGSKIFSSFLQVNDSFVIP
                     GLIGIPYNIIIIAAIALSAGKNVWILPAGALLAMASQLLFQLPFAFKKSYKYKPYINL
                     KDESIKELVNLVLPMLVGVAVGQLNIFVDRLLATTLGDGKLSALNYANRLNEFVMALF
                     VTSIITVIYPKLAKMSGKDNKEGFISTIVKSSNCIILVVLPISIGAIILAEPLVRILF
                     QRGKFDALSTDLTSIALRLYSLGLLACGVRDVLYRAFYSLSDTKTPMINGSIALIINI
                     VLNLILIRPLGHAGIAISTSTSNIITVILLFISLKKKNGYFGGDKIIKTGLKSLVASG
                     VMAVATLLIYNNLYAFMGSGTIKEIISVGAGVLGGASVYTVLIVLFKVEEMDLAFEFL
                     RKGKQKLLRR"
     gene            7195..8901
                     /locus_tag="KRH23_002290"
     CDS             7195..8901
                     /locus_tag="KRH23_002290"
                     /EC_number="5.4.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016868 - intramolecular
                     phosphotransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HHS5225568.1"
                     /translation="MDYKNNYEMWLNSPYFDEQTKNELLSIKDDEKEIQDRFYKNLEF
                     GTGGLRGIIGAGTNRINIYTVRRATLGVLNYIMKTQGEEGKQKGIVIAHDSRYMSREF
                     CIEVAKTLSAYGVKAYIFEELKPTPELSFAVRYLKCAMGIVITASHNPKEYNGYKVYD
                     SDGGQICIDMANDIIAEVNKIDDYSTIKSIDFEEALSKNLITILDNEVDDEFIKAVKK
                     QVLRQNIIDEYGKKLKIIYTPIHGTGNKPVRKVLNECGFENVMVVKEQELPDSNFSTV
                     KYPNPEEKSVFNIAIEMAKNNGTDLIIGTDPDCDRVGIVVKDSSGEYVVLNGNQVGSL
                     LVRYILESLVEENKLPKNNPTIIKTIVTSELGAKIAKAYNVDCLNTLTGFKFIGEKIK
                     AFEESNDRSFIMGYEESYGYLIGTHARDKDGVVSSLMICEMVAYYSSKGMNLYEALID
                     TYNKFGYYKEDLKSVTLKGIDGIKKIKEMMLYFRSVKIDNVADVKVDKILDYKDGVDD
                     LPKSDVLKFLLEDGSWIAIRPSGTEPKIKFYFGANSDNQEDVEFKLNNLISYILNVVD
                     SI"
     gene            8923..9996
                     /locus_tag="KRH23_002291"
     CDS             8923..9996
                     /locus_tag="KRH23_002291"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004475 - mannose-1-phosphate
                     guanylyltransferase (GTP) activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0009298 - GDP-mannose biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-1-phosphate guanylyltransferase"
                     /protein_id="HHS5225569.1"
                     /translation="MKVYNVIMAGGGGTRFWPLSRQEVPKQLINLSGEDALINETINR
                     IDSLAKKDDLFIVTNEKQLEALKDIVKDKCLDSNILPEPCARNTAAAIGFAAFNIMKK
                     YGDGVMCVYPADHYIKDEKEFKSILEKAIYIAENNDKLVTIGITPTFPSTGYGYINFN
                     RENTIEDVAYEVVEFVEKPNYEIAKEYVNSKKYVWNSGMFVWKVSKILEDFKRYLPKV
                     YEKLEDISKYLGTKEEMEKIKEIYPTIQSISIDYGIMERSNDVIVVPGDFGWNDVGSW
                     DSLGAIYPTDDEGNIKRGENITIDTKNSIIYSDDKLISTIGISDLIVVSTNDAVMVCR
                     KDKAQDVKKIVEQLKEEDRQEYM"
     gene            10008..10730
                     /locus_tag="KRH23_002292"
     CDS             10008..10730
                     /locus_tag="KRH23_002292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HHS5225570.1"
                     /translation="MIPKKIHYVWFGGPKGNIENICINSWKEKLPEYEIVEWNEKNFD
                     IEKEIKGNKFLEECYKRKLWAFISDYTRIKVLYEQGGVYMDTDMQILKDITPLLENNR
                     LICGYEDDREYINGAIIGVEKGHPFLKDLLEYYEKEVLTSSLFTIPKIMTHLMEKNYK
                     KIDPNNYEEGIRVYDKEYFYPFGFKEDFTPECITENTFGIHWWGKSWAKKRNYFLESK
                     HLTGVNKIWKCCKIFASNTLRS"
     gene            10746..11903
                     /locus_tag="KRH23_002293"
     CDS             10746..11903
                     /locus_tag="KRH23_002293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide polymerase"
                     /protein_id="HHS5225571.1"
                     /translation="MKTLNDDRNIMIRKYLYIFVLFIILLRKYMISFIDPNMDIGMIK
                     SALFYSSIGILMLLFLFDKRKSITEMVLVGVCVLLYLLNREGAILLIVLLAVSAKQID
                     DKFIVKNYLIISACFLMVAILLFNLFPSLIFNQEVHYRYIEKIDMLVTRMDFGLGNPN
                     SVFYHMVTIYAAYIFLRYKDYNKWDRIILFGSAFFVYQTTYSRTGFFTILAGLIFVEI
                     IRWIDIKKIKGLPMLLKTLPIILTLFSVIIGTVFDKSTLLNRLLASRPKFWHVYLAEK
                     GNFLKPFGNSYSPAIKATNPLDSSYVYIISVLGVVACILFMYLMYKGIESFIEKDKKA
                     YLVALFIFLLYSFAENLLLEASFSFAVVLLIKEVILNDKREIDLWKMKSRR"
     gene            11906..12745
                     /locus_tag="KRH23_002294"
     CDS             11906..12745
                     /locus_tag="KRH23_002294"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HHS5225572.1"
                     /translation="MLISLIMPTLNRYDDIYLLMDSLENQTYKNFELIVVDQNDNSKV
                     KEIVDKYIDKLDIKYIKSSKKGLSYNRNVGIDNAVGQIIGFPDDDCVYENDTLEKVIN
                     FFNKNKDYKIYSCKTMDSNKVDAFKKMYDGTCDITSSNVLDTITSITFFIDFEGKDYT
                     RFDEKLGVGGEFGAGEEIDYVLNLLSLGFKGKYFGNDIIYHPAKKHSKSKEKYQKDYN
                     YGRGFGALCKKEIVYRKNYKFAKVMVSKLVRNIGGLILSSNRDYHSATIKGRINGFRQ
                     YKL"
     gene            12760..13935
                     /locus_tag="KRH23_002295"
     CDS             12760..13935
                     /locus_tag="KRH23_002295"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047355 - CDP-glycerol
                     glycerophosphotransferase activity [Evidence IEA];
                     GO_process: GO:0019350 - teichoic acid biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-glycerol glycerophosphotransferase family
                     protein"
                     /protein_id="HHS5225573.1"
                     /translation="MDKVKFLINMLLAFFIYPFNKHKFNGRDIWLIGGHSGDIYNDNS
                     KFFYEYMLKEHNDVETYWVVNKDSKVFDKIPGKKLIRGSVENYLYYYNSKAIVFSHAP
                     SADIAPYNFAVPVLNYFHKKTIKVFLNHGTISFKKRKPMNKKFKNIIDNLYKSYNIVT
                     ASSEFERNVMVNDWGMLDDSVYIIGNARYDNLPTNEVAQTRDILYTPTWRDWIKFSSG
                     KFTDTDYFKNIMNFLNDDKLNKILDEKDINVKIYMHHLMHEFIDDIKENITGKRIVFL
                     DKGVTLANEIRKSAANITDYSSVAIDFLYMNRPILFYQFDLDEYMEKVDSYIDLKSEM
                     FGSLAYNNDEAVNKLIDIIENNFEVMDNQKNERNKFFRYNDNKNCKRIYDCVLSKIK"
     gene            13964..14713
                     /locus_tag="KRH23_002296"
     CDS             13964..14713
                     /locus_tag="KRH23_002296"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HHS5225574.1"
                     /translation="MKKNLVSIITPMYNSEKFIEATIKSVLNQTYQEWEMLIIDDCST
                     DNSPNIVKSYMQQDSRIKCIKTETNKGVSNARNLALSKATGQFIAFLDSDDQWNSSKL
                     EKQVNFMLENDYVISFTSYELMDENDKKLNKVIKVPPNVDYRRLLKGNILGCLTVVID
                     KSKLDFEIRMSGVRHEDYVLWLSILKKGHIAHGINEVLALYRKSSNSLSGNKIKAAMW
                     TWNIYRNIEKIPLYKAIYYFINYGINGIKKS"
     gene            14735..15643
                     /locus_tag="KRH23_002297"
     CDS             14735..15643
                     /locus_tag="KRH23_002297"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006486 - protein glycosylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family A protein"
                     /protein_id="HHS5225575.1"
                     /translation="MYKYKFTVFTPTYNRAHLLENLYNDLKAQTYDFNDFEWLIVDDG
                     SSDSTKELVEKFISENKLNIRYIYKENGGKHTAINLGVKNADGELFFIVDSDDGLIKD
                     SLEIANDEWDSLENKEGFSGVVGLCVYPSGDLIGTEMPEDKKICHFADLYFKYGVKGD
                     KSIVFVTDELIKFPFPERKEVRFLPESVVWNEMSKYYKVICVNKPMIIRDYLDDGLTK
                     NILSKNALRGRALEFLYLINQNTYPLSRYPYMWIKNYINLARYSLLSDSHYFGELRKV
                     SDKLLYLALFPLGYYKYIGQRKLVSK"
     gene            15691..16443
                     /locus_tag="KRH23_002298"
     CDS             15691..16443
                     /locus_tag="KRH23_002298"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HHS5225576.1"
                     /translation="MNEPLVSIITPVYNSEEFLSETIKSIQNQTYKNWQLLLVDDCSK
                     DNSSEIIKSFRKEDARIKYIKLEKNSGAAVSRNVGIKNAEGRFIAFVDSDDLWDSRKL
                     EIQIEYMLKENVGFSFTSYRYMRQDGSKTNKVARAPKKIDYEGLLRNTIIGCSTVVID
                     KEIVGEFSMPLVRRGQDTATWLQLLKKEKYAYGIQEDLVNYRLVGNSISSNKIKALKR
                     TWNTYRNVENLSLPKSLYVFCFYVFNAIKKRV"
     gene            16397..17764
                     /locus_tag="KRH23_002299"
     CDS             16397..17764
                     /locus_tag="KRH23_002299"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose dehydrogenase family protein"
                     /protein_id="HHS5225577.1"
                     /translation="MYFVSMFLMPLKKEYKFYILGGKKMKIAIAGTGYVGLVTGVCLA
                     EVGNENVVCVDVDEQKVKSMKLGIAPIYEEGLEELMVKNYNRGRIDYTTDYKKAYEDV
                     DVILIAVGTPERSDGSANLDYIKAVAKQIAETVTKDTLVVIKSTVPIGTNEEIEDYIN
                     RNLKNDVKVELASNPEFLSQGTAVKDTLHASRIVIGVESEWAREILEEIYKPFNQPII
                     VTNRNSAEMIKYASNNFLALKISFMNDIANLCEIAGANIEDVALGMSYDDRIGSKFLK
                     AGIGYGGSCFPKDTKALHWLSEHNGYELKTVKAAIEVNESQKLKLVRKASKLVESFQD
                     MKVAVLGLTFKPDTDDIREAPSIPNIKYLLERGARVTVYDPIGVNNTKKIFGDSILYA
                     DSVDDAIEDAEICFIMTEWKDVLNYDIHKYKEKMKNPLVLDGRNCYKIKDMEELGIEY
                     YSIGR"
     gene            17770..18861
                     /locus_tag="KRH23_002300"
     CDS             17770..18861
                     /locus_tag="KRH23_002300"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HHS5225578.1"
                     /translation="MKTVCYLADGSNPHTLKWCSFFKNKGYDIHVISLNGGHMEGIKI
                     YNFGSNVEELKNENISKKTGYLGSIKQIKKLVNEIKPDILHAQYASSYGFIGSLLGYH
                     PYIISVWGTDIYDFPNNGFIQKQIIKHNFRKADYIFSNSRDMAKEANKYTAKHVDVTF
                     FGVDMDRFKPMEVEKEDAFVIGIIKSLEKKYGIEYLIQAFKMLKDEYKDKKIILKIGG
                     SGSQMDNLINLAKELGIENDVQFLGRISPENVSKTFNSFDVTVFPSLREGFGVAAIES
                     EACEVPVIVTNVGGHPESVWENETGLIVEPKQPEEIKNAIIKLMENDELRLNMGKKGR
                     QFVRENYEVNLNFNDIEKIYDSIFDKYKK"
     gene            18945..20858
                     /locus_tag="KRH23_002301"
     CDS             18945..20858
                     /locus_tag="KRH23_002301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HHS5225579.1"
                     /translation="MRESIDLEKESFFNRLFKKYKFRHLTLLILDICSVLVAFRMSLS
                     LTGNLNAFTTNDIIISACTYIVLHIVSFRLFKCYNTLWRYAGEEEIISIFVATLAYLI
                     PIYIINKLLGFDYPIMFYVLNTIFIIMFTSGARIAYRAIRIVMNKTYSRGKVSNILII
                     GAGDAGEMVIQELKRNPELKKVAVAIIDDDKNKIGRIIHNVKIVGTTSDIKDVVEKYN
                     VDEIIFSIANIEKRRKKEIIDICKNTNCKIKTIPGIYEIIDGKVDIKQIREVEIEDLL
                     GREPIKTNLREISNYIEGKVILITGGGGSIGSELCRQIAGFNPKELIIVDNYENNAYS
                     IQQELLRKYKNKLDLKTVIASIREEKRMDEIFNKYKPEVVFHAAAHKHVPLMESSPGE
                     AIKNNIFGTLNIAGLSSKYRAKKFVLISTDKAVNPTNIMGATKRAAEMIIQTMNAESQ
                     TEFVAVRFGNVLGSNGSVIPLFKKQIEDGGPVTVTHPDIIRYFMTIPEAVGLVIQAGA
                     MAKGGEIFVLDMGEPVRILDLAKNLIKFSGFEPDVDIKIEFSGLRPGEKLYEELLMSE
                     EGLLDTEHKKIFIGRPIDVDREKITKYLKLLREITNNEEVEKIDGIMRELVPTYIKPE
                     DANIKEIATTREK"
     gene            21057..21764
                     /locus_tag="KRH23_002302"
     CDS             21057..21764
                     /locus_tag="KRH23_002302"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0000270 - peptidoglycan metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HHS5225580.1"
                     /translation="MMNIKNKKHILKKFIAMVLIAGVVTVEAGAITASAAEPTNSPMS
                     ATVDQCDFLNVRSGASANDAVVGKINTGDKVEVLELHSNGWIKIKSVDNVTGWVNGDY
                     LTIQGGNVDAKVQNVLNLAFKQQGKPYKWGATGPNSFDCSGFTSYVYKNGAGVNLPRV
                     SRSQATVGKKVSRAELKPGDLVFFGSGGSINHVGLYVGDSKFIHSPQTGDVVKVTSMA
                     PGTNYARRLITATRVLQ"
     gene            22066..24177
                     /locus_tag="KRH23_002303"
     CDS             22066..24177
                     /locus_tag="KRH23_002303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding glycosyl-hydrolase Cwp19"
                     /protein_id="HHS5225581.1"
                     /translation="MKKISILVLSLIMTLTMCSVSSFADSSNDKEMRAAWISTVYNLD
                     WPKTKNNEAKQKKEYTDLLDKLKSVGINTAVVQVRPKSDALYKSNINPWSEYLTGTQG
                     KDPGYDPLPFLIEEAHKRGMEFHAWFNPYRITMADESIDKLPANHPAKKNPSWVVKHG
                     NKYYYDPGLPEVRKYIVDSIAEVVQNYDIDGVHFDDYFYPGVSFNDTATYQKYGKGQN
                     KDDWRRENVNTLLRDVKASIKSIKPNVVFGVSPAGIWRNKSSDPTGSDTSGNESYVGT
                     YADTRAWIKQGLIDYVVPQLYWPIGLKAADYSKLVAWWANEVKGTNVDLYIGQGIYKQ
                     GQSSYGGQNIAKEIVQQVTLNRKYSEIKGSMYFSAKDIANSTSIQKDLKSLYSSSEEP
                     VTPPSNVKVEKLRGDERYDTAVAISKKGWATNSDTVVLVNGYSIVDGITSTPLATSND
                     APILLVNKDNIPTSTKNELKRLNPSKVILIGGNNSIGDKVESEIKDTLSNVSINRVGG
                     SDRYSTSLMIAKELVKTNPVEKLYITSGTGEADSLSIASKAGEEKQPIVLVSKDNVSD
                     EVYNWISDLKVKDAYFIGGNLSISDSVINKLDKVITNDVSKNRIAGENREETNGKVIQ
                     KFYPNAEYSSMFVSKSNQLVDALTSGPLAAKLKSPVVMLGNSVTSAQKTALEPKKTTL
                     VYEAGDGINQNTLNTFLNLVK"
     gene            complement(24375..25340)
                     /locus_tag="KRH23_002304"
     CDS             complement(24375..25340)
                     /locus_tag="KRH23_002304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0070726 - cell wall assembly [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HHS5225582.1"
                     /translation="MSKLKKFVILLAFLVVIFPISVYGYFYYKLSAIHDSSISSDLLN
                     NNDHKNEDGIINILLMGTDARPNEDSSRSDAMMILTIDNKHNDIKLTSLARDSYVDIP
                     GHGKQKLTHAYAYGQADLLIQTIEENFNIDIQNYACVNFESFMYIIDAIGGVEVTVEK
                     GEIRELNKFIPETYKWNKSDDKGSIQYIRNSGKQTLNGYQALSFARIRHNDTAFARDG
                     RQRQIIQAIIKKTETLPVTKYPGLLDAVLPYVKTNMKPNAILSLGAQVLKMGDLNIKQ
                     FEFPIDDEIHSTGGIYGKAGWVLRFDPDTLDILHDFIFNDIEFKQ"
     gene            complement(25625..26581)
                     /locus_tag="KRH23_002305"
     CDS             complement(25625..26581)
                     /locus_tag="KRH23_002305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0070726 - cell wall assembly [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HHS5225583.1"
                     /translation="MSGLKKFVIFLALLVIAFPVSIYGYVFTKLKTIQDDSINTEALS
                     SNDYKNEENITNILLLGTDARPGEEVSRSDAMMILTIDNKNKSLKLTSLNRDTYVNIP
                     GRGEQKLTHAYVYGQANLLIETIEENFQLDIQNYAVVDFFSFMDIVDALGGVTVTVDK
                     SEIRELNKFIPETYKWNKNDNKGSLKYIRNSGEQKLNGYQTLAFSRIRKNDSTDERDR
                     RQRSVIQSLINGVKDLPVTKYPNLVNTILPYVKTNMNPNEIISLGKELLSIGNLNLKS
                     MEFPLSTENGRKIGNAGYVIPFEEYELDAMHDFIFKDIMVED"
     gene            26949..27737
                     /locus_tag="KRH23_002306"
     CDS             26949..27737
                     /locus_tag="KRH23_002306"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HHS5225584.1"
                     /translation="MIKLIATDLDGTLLDEKSEINPEFYKVFKKLRERGIMFSAASGR
                     QYQNLIKKFEDIKDDMMFISENGTLVVYKGKEILSNPLNKELVNEIIETTRSIKGKKI
                     VMSGKKYAYIESKDEAFIQEVSTYYAKFKIVEDLTKVEGDILKIAVFDFKGAEHNNNI
                     YFEKFSDRAQVCISGVEWLDLTAKGANKGSAIKKVQKMLDIKYEETMVFGDQLNDVEM
                     MKSAYHSYAMENANEHLKQIARFRAKRNTENGVVDKIKEVIKIG"
     gene            complement(27860..28330)
                     /locus_tag="KRH23_002307"
     CDS             complement(27860..28330)
                     /locus_tag="KRH23_002307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4358 domain-containing protein"
                     /protein_id="HHS5225585.1"
                     /translation="MKKILILFFSIILSLGMVSCSSSGDYKNVSTSKIKKALKSSDLL
                     IKESKIFDAKDFNYFNDVEEDIIQGFVINSSEKLSLEDIIVIKTDEVDKIYKTLENYK
                     KDMIQAPFGEGHGEKINSEIANNTIIEKAGRYVYLISAENATQIENKILNIIKK"
     gene            28469..29113
                     /gene="uppS"
                     /locus_tag="KRH23_002308"
     CDS             28469..29113
                     /gene="uppS"
                     /locus_tag="KRH23_002308"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl diphosphate synthase"
                     /protein_id="HHS5225586.1"
                     /translation="MRIPKHVGIIPDGNRRWASQNGMTKDKGYESGIDPGLESYRLCR
                     DLGCEEVTFYGFTTDNTRRPSVQTKAFTKACIDAANILIDEGAALLVVGNTKSPMFPE
                     ELLPYTNRIKAKEGQIKANLLVNYGWYWDLNNISGVENVNKNNIQDYIQSFDVSRLDL
                     IIRWGGRRRLSGFLPVQSIYADFYVIDNYWPDFKSDDIKDAFSWYDTQDVTLGG"
     gene            29237..30061
                     /locus_tag="KRH23_002309"
     CDS             29237..30061
                     /locus_tag="KRH23_002309"
                     /EC_number="3.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008745 - N-acetylmuramoyl-L-alanine
                     amidase activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HHS5225587.1"
                     /translation="MSKGNNNNNSRNKSKKTSHLNRKKRKLNKKKLAVLICFTVLFLF
                     IAFKATQGVVALVKSMDKSNKTNQQQNVNSEQFDLGNEEENKKKKYTVFIDPGHGGND
                     KGTESKTSNRYEKDLNLQIAKKLANKLSKQKDIQVVVSRTDDTYISLKDRAILANNSS
                     ADVLVSIHLNAEKNGNTATGIETWYRNKATDGSKELAQTVQSTIVSYVKVRDRGIVEN
                     NFEVLRESNMPAILIECGFLTTPSEEQKIINEKYQDQLAEGIVQGVLSYLDSKGNK"
     gene            30376..31923
                     /locus_tag="KRH23_002310"
     CDS             30376..31923
                     /locus_tag="KRH23_002310"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0052621 - diguanylate cyclase activity
                     [Evidence IEA];
                     GO_function: GO:0071111 - cyclic-guanylate-specific
                     phosphodiesterase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="HHS5225588.1"
                     /translation="MNKNSMTRIYSLNKIIFIIIGILGIVLLTRHIEVDIKVLILILL
                     TLFSINVFTSYLKIKLYEDKINLGLINNSDKFINITKDENFLKHVQNYIISNEKENCV
                     MACFDLCRLKLINDIYGYELGDEVLNNILSNLKNYFGKEAIYGKLKSDVFVLIIKLEN
                     REQKIPYLVNLIKNKIVILSQIDSFKMDINIEASIGIYKFNNNEIDIKKAIDNADMAR
                     LKSKGLKHIEYVEFDNAMEEEIQSIMKIERDLFLAIKNKEFVIHYQPKVDSSTGNIIG
                     SEALIRWLHPSLGMVGPNKFIPIAEKNGLINNIGRWLIQEVFITINKWISEGINVLPV
                     SINLSRVELYKNDLVDFFKLMFNTYNIPKELIELEITETTALRDVKFISERLYEIKSL
                     GMNISLDDFGVGNSNFINLKGIPLDIIKIDRSLILDIVTNTKTKFMVKAIVNLSHDLN
                     VTVICEGVEDMHQVKVLSELGCNFIQGYVFFKPLDEMNYKKLLTDGSYINLKDTLLDK
                     CMTVEEE"
     gene            31926..32324
                     /locus_tag="KRH23_002311"
     CDS             31926..32324
                     /locus_tag="KRH23_002311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RrF2 family transcriptional regulator"
                     /protein_id="HHS5225589.1"
                     /translation="MISEDVDYSIRIIRAIFNNGEDKPIDAKMILKSEDIPILTLYRL
                     LRKLCANNILTFNKEDGKTYMLNVSLDTISLRTIVEVIDGKIYINKCTRYVSNCSNCL
                     KGCKVNRELLEIEKEIYKLLSRKSIRQILE"
     gene            32364..34097
                     /locus_tag="KRH23_002312"
     CDS             32364..34097
                     /locus_tag="KRH23_002312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Eco57I restriction-modification methylase
                     domain-containing protein"
                     /protein_id="HHS5225590.1"
                     /translation="MDDISQDNFLLSKEYENSLDVDTKKASGIYYTPKIIVDYIVKKT
                     LKNHDIIKNPYPRILDISCGCGNFLLEVYDILYDLFEENIYELKKKYDENYWTVDNIH
                     RHILNYCIYGADIDEKAISILKDSLTNKKVVNDLDESDIKINLFCCDSLKKKWRYKFD
                     YIVGNPPYIGHKKLEKKYKKFLLEKYSEVYKDKADLYFCFYKKIIDILKQGGIGSVIT
                     PRYFLESLSGKDLREYIKSNVNVQEIVDFLGANIFKNIGVSSCILTFDKKKTKETYID
                     VFKIKNEDICINKFETLEELLKSSKFEHFNINQRLLSDEWILVNKDDETFYNKIQEKC
                     KYSLEDIAISFQGIITGCDKAFILSKDDVKLNLVDDKFLKCWIKSKNINKYIVDKSEY
                     RLIYSNDIDNENTNKRILDEIIGLYKTKLENRRECKSGIRKWYELQWGREKLFFERKK
                     IMYPYKSNENRFAIDYDNNFSSADVYSFFIKEEYLDKFSYEYLVGILNSSVYDKYFKI
                     TAKKMSKNIYDYYPNKVMKIRIFRDNNYEEIENLSKQIISILLNKSIDKGKVEKLQIK
                     MDNLIMDSLGI"
     gene            34329..35540
                     /locus_tag="KRH23_002313"
     CDS             34329..35540
                     /locus_tag="KRH23_002313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HHS5225591.1"
                     /translation="MKGLVLEGGGTKGAYQIGAYKALRELGIEFQGVTGTSIGALNGA
                     YIVQNDIEVMEDIWLNYDYTHFMNIDRETYERFKNVDFTTKNLNAVFELINKARKNEG
                     IDISPLRQLMETTLNEDIIRKSKKDFGLVTVWWDKKINPYPLYIEDIPKGRLIDYLIA
                     SSSLPIFQTNMMDDKLYLDGMFCDNMPIGLLEDKGYEDVVVIRLIDDFIGKMNLNRHQ
                     NINIKTIIPSEYLGGSLNKDRDNVEKNIRLGYLDTMKAYERCTGIKYYFDVEYKYNEE
                     YCFDKFRSMSNETIQYICNLLNIKRDASLRTVMESVIPKLGEVLGLPKDFSYKDLFYC
                     IYEKKLEENNINRIKLYDFNKVIDVVNTNIDSNRNLASNFEVRPKISIKKNKNTKLLT
                     NCIIKDIKNQS"
     gene            35733..35993
                     /locus_tag="KRH23_002314"
     CDS             35733..35993
                     /locus_tag="KRH23_002314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HPr family phosphocarrier protein"
                     /protein_id="HHS5225592.1"
                     /translation="MEKVVSIKNASGLHARPAGMFVKKAAEFKSTVEVVAKDKTVNAK
                     SIMGIMSLGLAQGEELKLVVNGEDEEVALAAMVELVESGFGE"
     gene            36347..38059
                     /gene="ptsP"
                     /locus_tag="KRH23_002315"
     CDS             36347..38059
                     /gene="ptsP"
                     /locus_tag="KRH23_002315"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008965 - phosphoenolpyruvate-protein
                     phosphotransferase activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HHS5225593.1"
                     /translation="MAYKGIGASPGVALGKALVVEHSELVIEKKSIDNVEAEIAKLED
                     AVAVSKEELVKVKEKASEELGAEEAEIFEAHLLVLEDPELIGSAIDKIKTESVNAEYA
                     LNEIKEMFVSMFESMDNEYMKERAADIKDVTNRILRHILGIKVVDLSALSEEVVLIAH
                     DLTPSDTATMNKKMVLGFLTDIGGRTSHTAIMSRTLEIAAIVGLNDITSKVKDGDFVV
                     FNGDTGEVIVNPDEETINKYTELKAKYEDERKALQLLKGKPSVTLDGKHVELAGNIGT
                     PNDIEGLIKNDAEGVGLYRTEFLYMDRDSFPTEEIQYEAYKAVLEGMDGKPIVIRTLD
                     IGGDKELSYLSMEPEMNPFLGYRAIRLCLDRKDIFKTQLRALYRASVHGRLRIMFPMI
                     SSLEELLQAKEVVKEVLAELDSEGVAYAKDVEIGMMIEVPSAAVISDVLAKHVDFFSI
                     GTNDLIQYTCAVDRMNQKISYLYNQFNPAVLRLIKTVIDNAHKEGKWAGMCGESAGDQ
                     KMIPILLGMGLDEFSMSPISILPARKLITSVKESDMKKLADDVLNMGTAEEIKSYIEK
                     TFNI"
     gene            complement(38851..39516)
                     /locus_tag="KRH23_002316"
     CDS             complement(38851..39516)
                     /locus_tag="KRH23_002316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5225594.1"
                     /translation="MKGNIVQYNFADIEEEVYSLDYAIAWNTDEENVNIIPFTNKFCK
                     ESIESFCLGKINNFVEILNEGFVENHHYVHLDKMISVPKKKVNLVYQQDTHGYLLRDD
                     NDNLIPAKITSEQSKSISSKMELFCAGEEKCLINILLKADPSYILDVDSIKDKNILNL
                     GYESIDRYKEYNFDDDKILIFFINKKRYSVIMKKTNNSDNDLVSRNNAIKELFTNKAG
                     NLN"
BASE COUNT        15779 a         4148 c         6920 g        12697 t
ORIGIN      
        1 aatttcaaat aatgctgtag attctaaact tacgaatagt aggattaaat caatagatat
       61 aataagaggg ctatcaatag ccctcatgat agtctgcaat aatcctggga cttggatgag
      121 aatgtatcct caattaagac atgctgtatg gcatggtgta acacttgcag attttgcatt
      181 tccttttttt gttatatctt taggtgttac aattccaata tcaataaata gtaaactaaa
      241 aaataataaa tccacactga gtataatact tagtatattc aagagaagta tcttattgat
      301 attatttgga tttttcttaa attacctagg aaatcctgat ttagatactg taagaatact
      361 tggagtactt caacgtatgg gattagtcta ttttgtgact agtttagtat atttactact
      421 aaaaaaatta aatgttggaa gtactgctac aataattact tttctatgta tatctacatt
      481 tataatagtt gggtactaca tcttagcaaa accttatgga tttgagctag aaggttctct
      541 tgcacagtta gtggatttac atttcttcaa gggacatttg tacaagccgg aatttgaacc
      601 agatggtttt ttaactagta tagtagcaat ttcttcaggt atgttgggat gcactatggg
      661 atgtgtactt ttaaaagaaa acctaggaga atataaaaaa ttctttaaaa tactggttat
      721 gagcataatc ctgctaatat gtgcttttat ctttaatcag tattttccat ttaataaaag
      781 attatggtct agctcatttg tacttttaat ggctggcagt tatggtatat tactgtcaat
      841 attttatttt atatgcgaca tcaaaaataa aagtaaaata tttaccccaa taatagcact
      901 tggaagtagc cctattttta catatatgtg ccttgaaata ttgagtcatg ttttttggaa
      961 tgttccaaaa cttacgaaca aagtcgatta tccaactacc ttggtagagt ggactacata
     1021 tgaacttata acaccttggg caggtacaac ttgggattct cttatatttt ctttattgta
     1081 tgtcctattc tgggttatag taatgtctat aatgtacaag aaaaaaatat ttattaaaat
     1141 ttagtgcaat atttttagat gataaagtct ttgatttgtt caaatatacg gaaactatca
     1201 aatataatca aaatttctcc tcgataaaat ttaaaaacca tgccataaaa gattacaaaa
     1261 agtttacaat ttgtaatttt ttgtgctata atgaaaaaag atttacataa tattgaattt
     1321 atgtaatata aaacaagctt aagatgtatt aaaaaagatt taaagattta aagaaccaaa
     1381 aaattagggg ggatatgatg aaaaaaacaa caaaattatt ggcaacagga atgttgtctg
     1441 tagcaatggt ggcaccaaac gtagctttag cggctgaaaa tactactgca aatacagaat
     1501 ctaattcaga tattaatata aatttacaaa gaaaaagtgt agtgttagga agtaaatcta
     1561 atgcaagtgt aaaatttaaa gaaaaattaa atgctgattc aataacatta aattttatgt
     1621 gttatgatat gccacttgaa gctactttaa attacaatga aaagacagat tcatatgaag
     1681 gtgtaataaa ctataacaaa gacccagaat acttaaatgt atgggaactt caaagcataa
     1741 aaataaatgg taaagatgaa cagaaagttt taaacaaaga agacttagag tctatgggat
     1801 taaatcttaa ggattatgat gttacacaag agtttataat aagtgatgca aattcaacaa
     1861 aagcagtaaa tgaatatatg agaaaaactt ctgcaccagt aaaaaaactt gctggagcta
     1921 ctagatttga aactgctgtt gagataagta aacagggttg gaaagatggg tctagtaagg
     1981 ttgtaatagt taatggagaa ttagcagcag atggaattac agctactcca cttgcatcta
     2041 catatgacgc accaatatta cttgcaaata aagatgatat accagaaagt acaaaagcag
     2101 agttaaaacg tctaaatcca agtgatgtaa taattatagg tgatgatggt tcagtttcac
     2161 aaaaggcagt gtctcaaatt aaatctgctg taaatgtaaa tgtgactcgt attggtggag
     2221 ttgatagaca tgaaacatct ttacttatag caaaagaaat agataagtat catgatgtta
     2281 ataaaatata catagcaaat ggatatgctg gtgaatatga tgctcttaat atttcatcaa
     2341 aagctggtga agaccaacaa cctataatat tagctaataa agattctgta ccacaaggta
     2401 catataattg gttatcttca caaggtttag aagaagctta ttacataggt ggtagtcaaa
     2461 gtttatcatc aaaaattata gaccaaatat ctaaaatagc aaaaaatggt acttcaaaaa
     2521 atagagtttc tggagcagat agacatgaaa caaatgcaaa tgtaattaag actttctatc
     2581 cagataaaga gttgagtgca atgttagttg caaaatctga cataatagtt gattcaataa
     2641 cagcaggacc tttagcagct aaattaaaag ctccaatact tataactcca aaaacttatg
     2701 tttctgcata ccatagtaca aacttatcag aaaaaacagc agaaacagta tatcaaattg
     2761 gtgatggaat gaaagatagt gttataaatt ctatagcatc tagtttatca aaacacaatg
     2821 caccaacaga accagataat tcaggttcag cagcaggaaa aactgtagtg atagacccag
     2881 gtcatggggg ttctgattca ggggcaacaa gtggattaaa tggtggagca caagaaaaga
     2941 aatatactct taatacagca ttagcaacta ctgaatattt acgttcaaaa ggtataaatg
     3001 ttgttatgac tagagataca gataaaacaa tggctttagg agaaagaaca gcattatcaa
     3061 atactataaa gccagattta tttacaagta tacattacaa tgcgtctaat ggagctggta
     3121 atggtgtgga aatttattac aaagtaaaag ataaaaatgg tggaacaact aagactgcag
     3181 catcaaatat cttaaaaaga atactagaaa aatttaacat gaaaaataga ggaatcaaga
     3241 caagaacact tgataatgga aaagattacc tatatgtgtt aagaaataat aattatccag
     3301 caatacttgt tgaatgtgca tttattgaca ataagagcga tatggataag ttaaatactg
     3361 cagaaaaagt aaaaacaatg ggaactcaaa ttggaatagg aatagaagat acagtaaaat
     3421 aaaatagaaa atattaaagc aaaacatatc atctcctgtt ataatgtaaa atataacaag
     3481 agatgatata tttttgtaaa gaatcaaatt gtttacaatg atgtttcttg tattgataat
     3541 ctgctcatta ttgagtataa tatagaaata agtcaaaaat aagatagaaa taagttgaaa
     3601 ttaagaatta aaaaaatttt tattccaata tggaggtaac tatgtctgga tatactaatg
     3661 atgagtgtga aatacctaaa attaaaagct atccaggggc agataaagaa attgcaagtg
     3721 agattgacta tagcatagta aaaggaacag ttttattcga cttgtaccaa agaattatgg
     3781 atttagtttt atctataata ggacttgtga taggtttacc tttaatagca atatttggaa
     3841 ttcttattaa aatagaggac aaaggaccaa taacttataa gcaagaaaga ctaggaaaat
     3901 gcgggagaag attctatata tataaattga gatctatgag aacagacgca gaaaaatttg
     3961 gcgcacaatg ggctgaaaaa gatgatccta gaataactaa ggttggaaag tttattagga
     4021 aaactagaat tgatgagatt ccacagctgt ttaatatatt aaagggggac atgggcttaa
     4081 taggtcctag accagagaga ccgaacttta ctgttcaatt taatgaggaa atacctggat
     4141 ttatcaacag gctcgctata aaacctgggc ttacaggttg ggcacaagta aatggtggat
     4201 acgaaatcac tcctgaagaa aaacttaaag aagatattta ctatataaaa aataggagta
     4261 tattacttga ctttaagata ctctttaaaa ctgttaaagt agtattgaca ggagacggag
     4321 ctagataatt taaaaatatt agattactaa tcaatgaaaa agctctttaa aaagagcttt
     4381 tttattgtca aaaaatacaa aaaagaaaag gaatgagaac ttatgattaa aaaaatttct
     4441 actatattat cgttagtttt gttaatctct atttctagta cgataggagt atttgcagat
     4501 gcaaatccca aaagagaatt gatagaaggg agtataccag agatttcgac agaattaaat
     4561 aaaagagcat ttaaggattc taaagaagta attcttgtaa atgaagagtc aattgtagat
     4621 agtataagtg caacaccttt agcatatgca aaaaatgctc caatagttgt aactaagagt
     4681 aaaaatcttg gtagagtaac aagaaattat ctaaaagaac taggtccaga gaaggttacg
     4741 atagtaggtg gtttaaaggc agtatctaaa gatgctgaac gtaatataga aaaaatggga
     4801 atgaaagtag aaagaataag agggaaagac agatatgata catctttaaa gatagctaga
     4861 gaaatgtata gaacagtagg atttgatgaa gcatttttac ttagctcaac aacaggatta
     4921 gagaacgcca tatctgtata ttcttatgcc gctaaaagtg gaatgccaat aatatgggct
     4981 aaagatgaag ggtttgagga acaaattgat ttcttaaaag gcaagaatct taaaaaaata
     5041 tatgcattag gtgattcaaa agagtttatt gcagagattg attctaactt aaaaaatata
     5101 gaaggaataa agcaaataaa taagtcaagt acaaatgttg atttaataaa gaagttttat
     5161 gatgaaaaag atataaagaa aatctatact gctagattag actttggtag tagatctgat
     5221 gtaaacgaat atatttcttt gggagtagta tcagcaaaag aaaatatgcc aatactgatt
     5281 tgtagtgata acttaagtcg tgcacaagat aaattcttga aagatagcaa tataaatgat
     5341 gtagttgaag ttgggtatac agtaggtgat tatagtctat ttaagagcat atttaatcta
     5401 acattcttat cttgtatagt attaatacta ttattactat tgattacatt tagggcactt
     5461 agatatgagt cgaaatagtt tttgatttat aaggaagctt ttcataggtt aaatttactt
     5521 aattagaata atgtttataa gcagttttaa aagttctact tttagagttt aaattagata
     5581 aggagaaaga agatgtcaaa aacagctaaa gcagcattgt ggattatggc agccactatg
     5641 ttttcaaaag tattaggttt ccttagagaa cttgtacttg caaatttcta tgggacaggt
     5701 atgtatgcag acgtatttgt attaacatta aatatacctg gcttaatcat agcagtcata
     5761 ggctctgcag ttgctacaac ttatatacct atgtactttg agacaaagaa aagactcgga
     5821 gatgaaggtg ccttaaaatt tactaataat gttttaaata tatgctatat aatggctata
     5881 gtaatagcta ttattgggct tttatttaca gagcaatttg ttacagtatt tgcagcagga
     5941 tttagaaacg accctgctaa gttccaagca gcaatattat ttactaaaat aatgatttca
     6001 ggagttttat tcctgagtgg aagtaagata tttagttcgt ttttacaggt gaatgacagt
     6061 tttgtaattc ctgggcttat aggaatccca tataatatta taataatagc agcaatagca
     6121 ctaagtgcag gtaaaaatgt atggatactg ccagcaggag cattattggc tatggcgagt
     6181 cagctattgt ttcaactgcc atttgcgttt aagaagtcct acaagtataa gccatatata
     6241 aatttaaagg atgagtctat aaaagagtta gtcaacctag tattgcctat gttggtagga
     6301 gtagctgttg gacagttaaa tatatttgtt gaccgattat tggcaaccac tttgggtgat
     6361 ggaaagttgt ctgctcttaa ctatgcaaat aggctaaatg agtttgttat ggcattattt
     6421 gttacatcta taataacagt tatatatcct aaactagcaa aaatgtctgg taaagataat
     6481 aaagaaggat ttataagtac tattgtaaaa tcttcaaatt gtattatatt ggtggtgctt
     6541 cctatatcta taggagctat tatattagca gagcctcttg ttagaatatt attccaaagg
     6601 ggtaaatttg atgcgttatc aacagacctt acatctatag cgcttagatt atattcacta
     6661 ggtttattgg cttgtggagt aagagatgtc ttatataggg cattttactc tctttcagat
     6721 acaaaaacgc caatgataaa tggaagtata gctttaataa taaatatagt tcttaattta
     6781 atattgataa gaccattggg tcatgcaggt attgctatat caactagtac atcaaacata
     6841 attacagtta tattattatt tatatctctt aaaaagaaaa atggatattt tggaggggat
     6901 aaaattataa agactggtct aaaaagtttg gtagcatctg gtgtgatggc agtagctact
     6961 ttattgatat ataataatct atatgcattt atgggttcag gaacaattaa agaaattata
     7021 tcagttggag ctggagtatt aggtggagct tctgtatata ctgtattgat agttttattt
     7081 aaggtagaag agatggattt agcttttgaa tttttaagaa aaggaaaaca aaaactactt
     7141 agaagataga taattacctt gaaattttaa attagagtca gaaaggatga aaatatggat
     7201 tataagaata attatgagat gtggttaaat tctccttatt ttgatgaaca aacgaaaaat
     7261 gagctattaa gtataaaaga tgatgaaaaa gaaatacaag atagatttta taaaaattta
     7321 gagtttggaa caggtggttt aagaggtata ataggagcgg gaactaatag aatcaatatt
     7381 tatactgtta gacgtgcgac actgggcgtt ttaaattata tcatgaaaac tcaaggagaa
     7441 gaaggtaagc aaaagggaat agttatagca catgatagta gatacatgtc tagggagttt
     7501 tgtatagaag tagcaaagac tttaagtgct tatggtgtaa aggcttatat ttttgaagaa
     7561 ttaaagccta caccagaact ttcttttgct gttagatatt taaagtgtgc tatgggaata
     7621 gtaataacag caagtcataa tcctaaagaa tacaatggat ataaagtata tgactcagat
     7681 ggtggtcaaa tctgtataga tatggcaaat gatataatag cagaagttaa taagattgat
     7741 gattacagta ctattaaaag tatagatttt gaagaagctt tatctaaaaa tttaataact
     7801 atattagata atgaagtaga tgatgagttt ataaaagctg ttaagaagca agttttaaga
     7861 caaaatataa tagatgaata cgggaaaaaa ttaaaaataa tatatacacc tattcatggt
     7921 acaggaaata agccagtaag aaaagtctta aatgaatgtg gctttgaaaa tgtaatggta
     7981 gttaaggagc aagaattgcc agattctaat ttttcaacag taaagtatcc taatcctgaa
     8041 gaaaagtcag tgtttaatat agctattgaa atggcaaaga ataatggcac tgatttgata
     8101 ataggaacag accctgattg tgatagagta ggtatcgttg taaaagattc aagtggtgaa
     8161 tatgtagtct taaatggaaa tcaagtcggt tcacttttag ttagatatat attagagagt
     8221 ttagttgaag aaaataaact tcctaaaaac aatcctacaa taataaaaac tatagttaca
     8281 tcagaactag gtgcaaaaat agcaaaagct tataatgtag attgtttaaa tactttaaca
     8341 ggatttaaat ttataggaga aaaaataaaa gcgtttgaag aaagcaatga tagaagtttt
     8401 ataatgggat atgaggaaag ttatggttac ttaattggaa ctcatgctag agataaagat
     8461 ggtgttgtat cttcacttat gatatgtgaa atggtagcat actattcttc aaaaggtatg
     8521 aacttgtatg aagctttgat agatacatat aataaatttg gatactacaa agaggactta
     8581 aagtcagtaa ctttaaaagg catagatgga ataaaaaaaa taaaagagat gatgctttac
     8641 tttagaagtg ttaaaataga taatgtggct gatgtaaaag tagataaaat tttagactat
     8701 aaagatggtg ttgatgattt acctaagtca gatgtactta aatttttact tgaagatggc
     8761 tcttggatag ctataagacc ttcaggtaca gaacctaaaa ttaaatttta ctttggagca
     8821 aattcagaca atcaagaaga tgtagaattt aagttgaaca atttaatatc ttatatatta
     8881 aatgtagtgg attctatata aaaagctaag gggagataaa caatgaaagt atacaatgtc
     8941 ataatggctg gaggaggagg aactcgtttc tggccactta gtagacaaga agtacctaaa
     9001 cagcttataa atttaagtgg agaagatgct ttaataaacg aaactataaa cagaatagat
     9061 tctctagcaa aaaaagatga tttatttata gtaaccaatg agaagcaatt ggaagcttta
     9121 aaggatatag taaaagataa atgtttggat agtaatatat tgccagagcc atgtgccaga
     9181 aatacagcag cagctatagg ctttgcagca tttaacataa tgaaaaaata tggtgatggt
     9241 gttatgtgtg tatatccagc tgaccattat ataaaagatg aaaaagaatt taaatctatt
     9301 ttggaaaaag ctatctatat agcagaaaat aatgataaac tagtaactat tgggataact
     9361 cctacatttc catcaacagg atatggatac ataaatttta atagagaaaa tacgatagaa
     9421 gatgttgcat atgaggtagt ggagtttgta gaaaaaccaa actatgaaat tgctaaagaa
     9481 tatgtaaact ctaaaaagta tgtatggaat agtggaatgt tcgtatggaa ggtatctaaa
     9541 atactagaag attttaagag atacttgcca aaagtatatg aaaaattaga agatataagt
     9601 aaatacttag gaacaaaaga agaaatggaa aaaataaaag aaatataccc aactatacaa
     9661 tcaatctcta tagattatgg tattatggaa agaagtaatg atgttatagt agttcctggt
     9721 gattttggat ggaatgatgt tggttcttgg gattctctag gtgcaatata tccaactgat
     9781 gatgaaggta atatcaaaag aggtgaaaat attactatag atactaaaaa ttcaattata
     9841 tattcagatg acaaattaat atcgacaata ggtattagtg atttgatagt agtatctaca
     9901 aatgatgcag ttatggtttg tagaaaagat aaagctcaag atgtcaaaaa aatagtagag
     9961 cagttaaaag aagaagatag acaagaatat atgtaggagg tgttcatttg attcctaaaa
    10021 aaatacatta tgtatggttt ggtggtccaa aaggaaatat agaaaatata tgtataaatt
    10081 cttggaaaga aaagcttcca gaatatgaga tagtagagtg gaatgaaaaa aactttgata
    10141 tagagaaaga aataaaagga aataagtttt tggaagaatg ttataaaaga aaactttggg
    10201 cattcatatc tgattataca agaataaaag tactctatga acaaggtgga gtttatatgg
    10261 atacagatat gcaaatatta aaggatataa ctcctctttt agaaaataat aggctaatct
    10321 gtgggtatga agatgataga gagtatataa atggtgctat aataggtgta gaaaaaggac
    10381 atcctttttt aaaagactta ttggagtatt atgaaaaaga agtacttact tcttcattgt
    10441 ttacaatacc aaagataatg actcatctta tggaaaagaa ttataagaag attgacccaa
    10501 ataattatga agaaggaata cgtgtttacg acaaagaata tttttatcct tttggattta
    10561 aagaagactt tacaccagaa tgtataacag aaaacacttt tgggatacat tggtggggaa
    10621 aaagttgggc taaaaagaga aattatttct tagaaagcaa acacttaaca ggtgtaaata
    10681 agatatggaa gtgttgtaaa atatttgcaa gtaatacttt acgaagctaa aagggagaaa
    10741 gtaaaatgaa gactttaaat gatgatagaa atattatgat tagaaaatat ctttatatat
    10801 ttgttttgtt tatcatatta cttagaaagt atatgatatc atttattgac ccaaatatgg
    10861 atatagggat gattaaatca gcgttatttt attcttcaat aggaatacta atgctacttt
    10921 ttttatttga taagagaaaa agtataacag aaatggtact agttggagtt tgtgtcttac
    10981 tttatttatt aaatagggaa ggagctatat tattaatcgt tttattagct gtatcagcta
    11041 agcaaataga tgataaattt atagttaaaa attatttaat aatatcagca tgttttttaa
    11101 tggtagctat attattattt aatctatttc cttcattgat atttaatcag gaagtccact
    11161 atagatatat agaaaaaata gatatgcttg ttacaagaat ggattttgga cttggtaatc
    11221 caaatagtgt attttatcat atggttacta tatatgcagc atatatattc ttaagatata
    11281 aagattataa taaatgggat agaataattt tatttggttc tgcatttttt gtttatcaaa
    11341 ccacatatag tagaactgga tttttcacta tattagcagg attaatattt gtagaaataa
    11401 taagatggat agatataaaa aaaataaaag gactaccaat gctcctaaag acattaccga
    11461 taatacttac tttatttagt gtaattattg gtacagtatt tgataaaagc actttattaa
    11521 ataggttatt agcaagtaga cctaagttct ggcatgtata cttggctgaa aaggggaact
    11581 ttctaaaacc ttttggaaat tcatatagtc ctgctataaa agcaactaat ccattagata
    11641 gttcttatgt atatataatt agtgtactag gagtagttgc ttgtatatta tttatgtatt
    11701 tgatgtataa aggaatagaa agctttatag aaaaagataa aaaagcatat ttagtagctt
    11761 tatttatatt tttactatac tcttttgcag aaaatttatt attagaagct tcatttagtt
    11821 ttgcagtagt attactaata aaagaagtga tattaaatga taaaagggaa atagatttgt
    11881 ggaagatgaa aagtaggagg tagtaatgtt aatatcatta ataatgccaa cattaaatag
    11941 atatgatgat atatacttac ttatggatag cttagaaaat caaacttaca aaaactttga
    12001 acttatagta gtagaccaaa atgataatag caaagttaaa gaaatagttg ataaatacat
    12061 tgataagtta gatataaagt atataaaaag ctctaaaaaa ggattgagtt ataacagaaa
    12121 tgtaggcata gacaatgctg tagggcaaat tataggtttc cctgatgatg attgtgtcta
    12181 cgaaaatgat acattagaaa aagttataaa tttctttaat aaaaataaag attataaaat
    12241 atacagttgc aaaactatgg attcaaataa agttgatgca tttaagaaaa tgtatgatgg
    12301 aacttgtgat atcacaagtt ccaacgtttt ggatactata acatccataa ctttttttat
    12361 tgattttgaa ggtaaagatt atacaagatt tgatgaaaaa ttgggtgttg gtggagagtt
    12421 tggtgctggt gaagagatag attatgtttt aaacttattg agtttaggtt ttaaaggaaa
    12481 atactttgga aatgatataa tttaccatcc tgcaaaaaaa cattctaaat ctaaggaaaa
    12541 gtatcaaaaa gattataact atggaagagg ctttggagcg ctttgcaaaa aggaaatagt
    12601 ctatagaaaa aattataagt ttgcaaaagt tatggtatca aaacttgtaa gaaatatagg
    12661 aggtcttata ttgagttcca atagagatta tcatagtgcc actataaaag gaagaattaa
    12721 tggatttaga cagtacaagt tataatgagg atggtgttta tggacaaggt taaattttta
    12781 ataaatatgc ttttggcttt ttttatatat ccatttaata agcataagtt taatggtaga
    12841 gatatctggc ttataggtgg acattcaggg gatatataca atgataattc aaagtttttt
    12901 tatgagtata tgctaaaaga acataatgat gtagaaactt attgggtagt aaataaagac
    12961 agtaaagtat ttgataaaat tccaggcaaa aaattaataa gaggaagtgt agaaaactat
    13021 ctgtattatt acaattcaaa agctatagta ttttcacatg caccatcagc agatatagca
    13081 ccatacaatt ttgctgtacc tgttcttaat tattttcata aaaaaacgat aaaagtgttt
    13141 ttaaatcatg ggactataag ttttaaaaaa agaaaaccta tgaacaaaaa gttcaaaaat
    13201 attatagata acctatataa aagctataat atagttacag caagttctga atttgaaaga
    13261 aatgttatgg taaatgattg gggaatgtta gatgactcag tttatataat tggaaatgca
    13321 agatatgaca atttaccaac aaatgaagtt gcacaaactc gagatatatt atatactcct
    13381 acatggagag attggataaa atttagttca ggaaaattta cggatacaga ttattttaaa
    13441 aatataatga attttttaaa tgatgacaaa ttaaataaaa tattagatga gaaagatata
    13501 aatgtaaaaa tttatatgca tcatcttatg catgagttta tagatgatat aaaagaaaat
    13561 ataacaggaa aacgaattgt gtttttagat aaaggggtaa ctctagcaaa tgaaatcaga
    13621 aaatcagctg caaatataac tgattattca agtgtagcca tagacttttt gtatatgaat
    13681 agacctatct tgttttacca attcgatttg gatgaatata tggaaaaagt tgattcatat
    13741 atagatttaa aaagtgaaat gtttgggtct ttggcttata ataatgatga agccgtgaat
    13801 aaacttattg atattattga aaataatttt gaggttatgg ataaccaaaa aaatgaaaga
    13861 aataagtttt tcagatataa tgataataag aactgcaaga ggatatatga ttgtgtatta
    13921 agtaaaatta aataaatatt ttataaatga tgaggaaggt aatatgaaga agaatttagt
    13981 atctataatt actcccatgt ataattctga aaaatttatt gaagcaacca taaaatcagt
    14041 attaaaccaa acttatcaag aatgggaaat gttaattatt gatgattgct caacagataa
    14101 tagtcctaat atagtcaaat cttatatgca acaggatagt agaataaaat gtataaagac
    14161 tgagactaat aagggtgtct ctaatgctag aaatttagca ctaagtaagg caacaggaca
    14221 atttatagct tttttagata gtgatgacca atggaatagt agtaagttag aaaaacaagt
    14281 aaattttatg ttagaaaatg actatgtaat ttcatttact tcatatgaac tgatggatga
    14341 aaatgataaa aaattaaaca aagtaataaa agttccacct aatgtagatt atagaagatt
    14401 attaaaagga aatatcttag gatgtcttac tgttgtgatt gataagtcta aattggattt
    14461 tgaaataaga atgagtggtg taagacatga agattatgtt ttatggttat cgatattgaa
    14521 aaaagggcat attgctcatg gaataaatga agttctagca ttatatagaa aatctagcaa
    14581 ttccctaagt ggtaataaaa taaaagctgc tatgtggact tggaatatat atagaaatat
    14641 agaaaaaata cctttataca aagctatata ctactttatt aattatggaa taaacggaat
    14701 caaaaaaagt tagacagaga ggaagattta attaatgtat aaatataaat ttactgtatt
    14761 tactccgacg tataacagag ctcatttact tgaaaatttg tacaatgatt taaaagctca
    14821 aacttatgat ttcaatgatt ttgaatggtt gattgttgat gatggaagta gcgacagtac
    14881 taaagagtta gttgaaaaat ttatatcaga aaataaatta aatataagat atatatacaa
    14941 agaaaatgga ggaaaacata ctgcaataaa tctaggtgta aaaaatgcag atggagagct
    15001 atttttcatt gtagatagtg atgatggttt aattaaagat tctcttgaaa ttgctaatga
    15061 tgagtgggat tctttagaga ataaagaagg atttagtgga gttgttggac tttgtgtata
    15121 tccaagtgga gatttgatag ggacagaaat gcctgaagat aagaaaatat gtcactttgc
    15181 agacctatat tttaagtatg gcgttaaggg agataaaagc atagtatttg taactgatga
    15241 gcttataaaa tttccttttc cagaaagaaa agaagtgaga tttttaccag aaagtgtagt
    15301 atggaatgaa atgtctaaat actataaagt tatatgtgta aataaaccta tgataataag
    15361 agattatttg gatgatggtt tgactaagaa tatattaagt aaaaatgcat taagaggtag
    15421 agcattagaa tttttatatt taataaatca aaatacatat ccattaagta gatatccata
    15481 tatgtggata aaaaattaca taaatttagc cagatactca ttgttgtctg atagtcatta
    15541 ttttggtgaa ttaagaaaag tatctgataa attgttgtat ttagcattat tcccattagg
    15601 atattacaaa tatattggac aaagaaaatt agtatctaag taaacttgtt ggtatagtac
    15661 tgctagttgc tatataagga gagtaaaaat atgaatgagc ctttagtatc gataattact
    15721 cctgtttata attcagaaga gtttttatca gagacgataa agtcaatcca aaatcaaact
    15781 tataaaaatt ggcagctttt attagtggat gattgttcta aggacaattc aagtgaaatt
    15841 ataaaaagtt ttcgaaaaga agatgctaga ataaaatata taaagcttga aaaaaattct
    15901 ggagctgcag tatctagaaa tgttggtatt aagaatgcgg aaggtcgatt tattgcattt
    15961 gtagatagtg atgatttatg ggatagtaga aaattagaga ttcagataga atatatgtta
    16021 aaagaaaatg taggtttttc ttttacatct tatagatata tgagacaaga tgggtcaaaa
    16081 acgaataagg ttgcaagagc tcctaagaaa attgactatg aaggattact tagaaatact
    16141 ataataggat gttctacagt ggtcattgat aaggagattg taggagagtt cagcatgcct
    16201 ttggtaagaa gaggacaaga tactgcaacc tggttacagt tacttaaaaa ggaaaaatat
    16261 gcatatggga ttcaagaaga tttagtgaat tacagattag ttggaaattc tatatcaagt
    16321 aacaagataa aagcattaaa acgaacttgg aatacttata gaaatgttga aaatttaagt
    16381 ttaccaaaaa gtctatatgt attttgtttc tatgttttta atgccattaa aaaaagagta
    16441 taagttttat atacttggag gtaaaaaaat gaaaatagct atagctggga cgggatatgt
    16501 aggtttggtt acaggtgttt gtctagcaga ggtaggcaat gaaaatgtag tctgtgttga
    16561 tgtagatgaa caaaaagtta aatcaatgaa acttggaata gcacctatat atgaagaagg
    16621 cctagaagaa cttatggtta aaaattacaa cagaggaaga atagattaca ctacagacta
    16681 taaaaaagct tatgaagatg tagatgtaat attaatagct gtaggtacac ctgagagaag
    16741 tgatggctca gccaacctag attatataaa ggcagttgca aagcaaatag ctgaaactgt
    16801 gacaaaagat actctagtag taataaaatc tacagttcca attggtacaa atgaagagat
    16861 agaagattat ataaatagaa acctaaaaaa tgatgtaaaa gtagagcttg catctaatcc
    16921 agagttttta tcacaaggaa cagcagtaaa agatactcta catgcttcaa gaatcgttat
    16981 aggtgtagaa agtgaatggg ctagagaaat attagaggaa atctataagc cttttaatca
    17041 acctataata gttacaaata gaaatagtgc tgagatgata aaatacgcat caaataactt
    17101 cttagctctt aaaatatcat ttatgaatga tattgcaaat ctttgtgaaa tagcaggagc
    17161 taacatagaa gatgtagctt taggaatgag ttatgatgat agaataggaa gtaagttttt
    17221 aaaggcggga ataggatatg gtggttcttg ctttccaaaa gacacaaaag ctcttcactg
    17281 gttatctgaa cataatggtt atgaattaaa aacagtaaaa gctgcaatag aagttaatga
    17341 aagtcaaaaa cttaaattag ttagaaaggc atctaagtta gtagagagct ttcaagatat
    17401 gaaggttgct gttttaggtt tgacttttaa gccagatact gatgatataa gagaagcacc
    17461 atctatacca aatataaaat atttgctcga aagaggggca agagttactg tatatgaccc
    17521 aattggtgta aataatacta agaaaatatt tggtgactct atactttatg ctgattctgt
    17581 agatgatgcg atagaagatg cagagatatg ttttataatg acagaatgga aagatgtatt
    17641 aaattatgat atacataagt ataaggaaaa gatgaaaaat cctttagtcc ttgatggaag
    17701 aaattgttat aaaattaaag atatggaaga gttaggaatt gagtattatt cgataggaag
    17761 gtaaatatta tgaagactgt ttgttattta gctgatgggt caaatcctca tactttaaaa
    17821 tggtgtagtt tttttaaaaa taaaggatat gacattcatg taatctcttt aaatggaggt
    17881 cacatggaag gaataaaaat ttataatttt ggttctaatg tagaagaact aaaaaatgaa
    17941 aatatttcta aaaaaacggg atacttaggt tcaataaagc agataaagaa gctagtaaat
    18001 gaaataaagc cagatatatt gcatgcacag tatgcaagta gttatggatt tataggaagt
    18061 ctacttgggt atcatccata tattatttct gtttggggta ctgatattta tgatttccct
    18121 aataatggtt ttatacaaaa acaaattata aagcataact ttagaaaagc agactatatc
    18181 ttttcaaata gtagagatat ggctaaagag gctaataaat atacagctaa acatgtagat
    18241 gtaacctttt ttggagtaga tatggatagg tttaagccta tggaagtaga aaaagaagac
    18301 gcttttgtaa taggaattat aaagagttta gaaaaaaaat atggaataga atatttaata
    18361 caagcattta agatgcttaa agatgaatat aaagataaga aaataattct taaaataggt
    18421 ggctctggaa gtcagatgga caacctaata aatttagcta aagaattggg tatagaaaat
    18481 gatgttcagt ttttaggaag aatatctcca gaaaatgtaa gcaagacttt taattctttt
    18541 gatgtaactg tatttccttc tttaagagag ggatttggag tggcagctat agaatcagaa
    18601 gcatgtgaag tacctgttat agttacaaat gtaggaggac atccagaatc tgtatgggaa
    18661 aatgaaactg gcttaattgt agaaccaaaa caaccagaag aaataaaaaa tgctataata
    18721 aaactaatgg aaaatgatga acttagactt aatatgggta agaaagggcg tcaatttgtt
    18781 agagaaaatt atgaggttaa tttaaacttt aatgatatag aaaaaattta tgattctata
    18841 tttgataaat ataaaaaata aaatgaaaaa atacagcaaa agatagatgt tgttggctat
    18901 gcttaggtgc gtagcttttg ctgtttaaag gagggcttct agttatgcga gaaagtatag
    18961 atttagagaa agaaagcttt tttaataggc tttttaaaaa atataaattt agacatttaa
    19021 cactattaat tctagatatt tgtagcgtac tagtagcgtt tcgaatgtct ttaagcttga
    19081 caggtaattt aaatgcattt accactaatg atataataat ttcagcgtgt acatatatag
    19141 tacttcatat agtatcattt agattgttta agtgctacaa cacattatgg agatatgcag
    19201 gagaagaaga aattatatct atttttgtgg caactttagc ttatttaatt ccgatttata
    19261 taataaataa attattaggg tttgattatc ctataatgtt ttatgtatta aatacaatat
    19321 ttattataat gtttacaagt ggcgcaagaa tagcctatag agctataaga atagtcatga
    19381 ataagacata ttctagagga aaggtttcaa atatccttat aattggtgca ggagatgcag
    19441 gagaaatggt tatacaggaa ctaaaaagaa atccagaact taaaaaagta gcagtggcta
    19501 taattgatga tgataaaaat aaaattggaa gaataatcca caatgtgaaa attgtaggaa
    19561 caacttcaga tataaaagat gtggtagaaa agtacaatgt agatgagata atcttttcaa
    19621 tagcaaacat agagaaacgt agaaaaaaag agattattga tatatgtaaa aacactaact
    19681 gtaaaataaa gacaatacca ggaatttacg aaattataga tggaaaagtt gatataaaac
    19741 agattagaga agtagagata gaagacttgt tgggtagaga gcctataaaa acaaatttaa
    19801 gagagataag taattacatt gagggaaaag taatcctaat aactggagga ggaggctcaa
    19861 ttggttcaga gctttgtaga cagattgcag gatttaatcc taaagagctt attatagttg
    19921 ataattatga aaataatgct tactcaatac aacaagaatt acttagaaaa tataaaaata
    19981 aattagattt aaagacagta atagcatcaa taagagaaga aaaaagaatg gatgaaatat
    20041 ttaataaata taaaccagaa gtggtatttc atgcagcagc acataaacat gttcctctta
    20101 tggaatcgag ccctggcgaa gctataaaga ataatatatt tggaacttta aacatagctg
    20161 gcttgtcttc aaaatataga gctaagaaat ttgtccttat atctacagat aaggctgtaa
    20221 accctactaa cataatggga gctactaaaa gagctgctga aatgattata cagactatga
    20281 atgctgaaag ccagactgaa tttgttgctg ttagatttgg aaatgtgctt ggtagtaatg
    20341 gtagtgtaat tccacttttt aagaagcaaa ttgaagatgg cggaccagtg acagttactc
    20401 atccagatat tattagatat tttatgacaa taccagaagc agtaggctta gtcatacaag
    20461 ctggggctat ggctaaaggt ggagaaatat ttgtacttga tatgggagaa cctgtaagaa
    20521 tattggattt agcaaaaaac ttaattaaat tcagtggatt tgagccagat gttgatataa
    20581 aaattgaatt ttctggtctt agaccaggag aaaagttata tgaagaacta cttatgtcag
    20641 aagaaggtct gttggataca gagcataaaa agatttttat tggtagacca atagatgttg
    20701 atagagaaaa aataacaaaa tacttaaaac ttttaagaga aattactaac aatgaagagg
    20761 ttgaaaaaat agatggtatt atgagggaat tagtgccaac ttatattaaa ccagaagatg
    20821 ctaatatcaa agaaattgca acaactagag aaaagtagaa tatatttcta atttgtaacc
    20881 agggggagca aaaagaaaca aatatatact aaaaagaaac aaaagattac aaaaagatta
    20941 caaaaagatt acaaaaaagg ttgcaattta ttttgatgta agatagaatg ttaattagga
    21001 attggaaacg aaggaacaaa atgttaaatt ttcgaaagga ttaggtattt gagattatga
    21061 tgaatattaa aaataaaaaa catatattga aaaaatttat agctatggtg ttaatagcag
    21121 gagttgtcac agtagaagca ggagcaataa cggctagtgc agcagagcca actaattcac
    21181 ctatgagtgc aacagtagac cagtgtgatt ttttaaatgt aagaagtgga gctagtgcaa
    21241 atgatgcagt agtaggaaag ataaacacag gagacaaagt tgaagtttta gaattacatt
    21301 caaatggatg gattaaaata aaaagtgttg acaatgttac aggatgggta aatggagatt
    21361 atttaactat tcaaggtgga aatgtagatg caaaggtaca aaatgtttta aacttagcat
    21421 ttaagcaaca aggtaagcca tataaatggg gagcaactgg accaaattct tttgattgtt
    21481 ctgggttcac ttcttatgtc tataaaaatg gagcaggagt taatttacca agagtatcaa
    21541 gatcacaagc aacagtagga aagaaagtat caagagcaga attaaaacca ggagatttag
    21601 ttttctttgg ttcaggtggt tcaataaatc acgttggatt gtatgtagga gattctaaat
    21661 tcatacattc accacaaaca ggagatgtag taaaagttac tagcatggct ccaggaacta
    21721 attatgcaag aagacttata actgctacac gtgttttaca ataataatag atattgattt
    21781 acataggatt gaatattaac attaaatata taattacatt taatgtttta catagagatt
    21841 taagagttta gtaatattaa aatagtgatg aacgttataa aaacagcaaa gaagataaat
    21901 ttctttgctg ttttttttat aataaattat ttcatattat aatcaaatat caaatataaa
    21961 ttttaactat attattcaat atttgacaga taatatgaat tttagatata cttaataaga
    22021 agtatattgt agaaaaaata aatttaaaaa attaaggggg atgaaatgaa aaaaataagt
    22081 atattagtat tatcattgat aatgacactt actatgtgta gtgtaagttc atttgctgat
    22141 tcatcaaatg ataaggaaat gagagctgct tggatatcta cagtttataa tttagactgg
    22201 cctaagacta agaataatga agccaagcaa aaaaaggaat acacagattt attggacaaa
    22261 ttaaaaagtg taggaataaa tacagcagtg gttcaagtaa ggccaaaatc agatgcttta
    22321 tataaatcaa atataaaccc atggtctgaa tatcttaccg gtacacaagg taaagaccct
    22381 ggatatgacc cattaccatt tttaatagaa gaagcacata aaagaggaat ggaatttcat
    22441 gcatggttta atccatatag aataactatg gcagatgaga gcatagataa attgccagca
    22501 aaccatccag caaagaaaaa tccaagctgg gtagttaaac atggaaataa gtattactac
    22561 gacccaggtt taccagaagt tagaaagtac atagtggata gtatagcaga agtagttcaa
    22621 aattacgata tagatggagt tcattttgat gattacttct atccaggagt aagtttcaat
    22681 gatactgcaa cataccaaaa atatggaaaa ggacaaaata aggatgattg gagaagagaa
    22741 aatgtaaata ctctacttag agatgtaaaa gcgtctataa agagtataaa gcctaatgtt
    22801 gtatttggtg taagcccagc aggtatatgg agaaataaga gtagtgaccc aacaggttca
    22861 gatacatcag gtaatgaaag ttatgtaggt acatatgcag atacaagagc atggataaaa
    22921 caaggattga ttgactatgt agttccacaa ctttactggc caattggtct taaagcagca
    22981 gattattcta aattagtggc atggtgggct aatgaagtaa aaggaacaaa tgtagactta
    23041 tacataggac aaggtatata taagcaaggt caatcgagtt atggtggaca aaatatagca
    23101 aaagaaatag tacaacaagt aacattaaat agaaaatata gtgaaataaa aggtagtatg
    23161 tatttctcag ctaaagatat agcaaatagt acttctatac aaaaggattt aaagagttta
    23221 tattctagta gtgaagaacc agttactcca ccatctaatg ttaaagtgga gaaattaaga
    23281 ggcgacgaaa gatatgacac agcagtagca ataagtaaaa aaggttgggc tacaaattca
    23341 gatacagtag tattagtaaa tgggtactct atagttgatg gtataacatc aacaccactt
    23401 gctacatcaa atgatgctcc tatactattg gtaaataagg ataatatacc tacatccact
    23461 aagaatgagt taaaaagact taatccaagt aaagttattt taattggagg aaataactct
    23521 attggagata aagttgagag tgagataaaa gatacattgt caaatgtatc aataaataga
    23581 gttggtggtt cagatagata tagtacatct ttaatgatag caaaagaatt agtaaaaact
    23641 aatccagtag aaaaactata tataacaagt ggtacaggtg aagcagattc tctttctata
    23701 gcttcaaaag caggagaaga aaagcaacca atagtattag tatcaaaaga taatgtaagt
    23761 gatgaagttt acaattggat atcagattta aaagtaaaag atgcttattt tataggtggt
    23821 aatctaagta tatctgattc agtaataaat aagctggata aggtcattac aaatgatgta
    23881 tctaaaaata gaatagctgg agaaaataga gaagaaacaa atggaaaagt aatacaaaaa
    23941 ttctatccaa atgctgaata ttcatcaatg tttgtaagta aaagtaatca attggtagat
    24001 gcattaacat caggtccttt agcagctaaa ttaaaatcac cagtagttat gcttggaaat
    24061 agtgtaacat ctgctcagaa aactgcttta gagcctaaga aaactactct agtatacgaa
    24121 gctggagatg gtataaatca aaacacatta aacactttct taaacttagt taagtaataa
    24181 aaaagttaat ttaaaataca gagtatttta taaatgtaga ttaaaatgaa aattatcatg
    24241 ataaattaga aaataaaaaa gaactatatg cattttgtaa tcaagtgtac acagcaactt
    24301 gaaaataatt atgcgatata gttctttttt agtaattaat cttatacttt ttaataaact
    24361 ttatgttgaa ttttttattg tttaaactct atgtcattaa atataaaatc gtgtaatatg
    24421 tctaaagtat ctgggtcaaa tctaagaacc catccagctt ttccatatat accacctgta
    24481 ctgtgaattt catcatcaat aggaaattca aattgcttaa tatttaagtc acccattttt
    24541 aaaacttgag ctcctaaaga aagtattgca ttaggcttca tgttagtttt aacatatgga
    24601 agaactgcat ctaataaacc tggatattta gtaacaggta aagtttccgt tttcttgatt
    24661 atagcttgta taatctgtct ctgtctgcca tctctagcaa aggctgtatc gttgtgtctg
    24721 atacgtgcaa aagatagtgc ctgatatcca tttagagtct gctttccaga gtttctaatg
    24781 tattgtatgc tacctttatc atcactttta ttccatttat aagtttcagg aataaattta
    24841 tttagttctc gtatttctcc tttttcaaca gtaacctcaa cgccaccaat agcatcaatt
    24901 atatacataa atgattcgaa attaacacaa gcataatttt gaatatcaat attaaaattc
    24961 tcttcaattg tttgtattaa taaatcagct tgtccataag cataagcatg agtaagtttt
    25021 tgtttaccat gaccagggat gtctacatag ctatcacgag ctaatgatgt aagtttgata
    25081 tcattgtgtt tgttatcaat agtaagtatc atcatagcat ctgaccttga agaatcttca
    25141 tttggtctag catctgttcc cataagtagt atgttaatta tcccatcttc atttttatgg
    25201 tcattgttat tcaataaatc actacttatg ctcgagtcat gaatagcaga taatttataa
    25261 taaaaatatc catagacact tatagggaat attactacca agaaagccag tagtataaca
    25321 aatttcttta attttgacaa aagtacccct tctttcttct ttttcctgta tattttttaa
    25381 tagcatacac ttaattatat taaagtattg agatatattc aatacttgtt tcagttacaa
    25441 aaaaaagaca atgatataat ttataagaaa atttatcgac ctatatatat agttaaaagt
    25501 atatataata tattttttaa aagtaattta tattttaaaa taaaaacaca ccccataaat
    25561 acaaagtaat ttgcatttaa gaggtatgta tttatcatca aattattggt ttgttttgga
    25621 atttctaatc ttcaaccata atatctttaa atatgaaatc atgcattgca tctagttcat
    25681 attcctcaaa aggtattaca tagcctgcat tacctatttt tctaccattt tcagtagaaa
    25741 gaggaaactc catagatttc aaatttaaat ttcctatact taaaagttct tttcctaaag
    25801 atattatttc attaggattc atattagttt ttacatacgg aagtattgtg ttaactagat
    25861 taggatattt agtgactggt aaatccttaa caccatttat taaactctgt ataacacttc
    25921 tttgtcttct atctctttca tctgtactat cattttttct tatacgagaa aatgcaagtg
    25981 tctgatatcc atttaatttt tgctcaccag aatttcttat atatttaaga gaacctttat
    26041 tgtcattttt attccattta taagtttcag gaataaattt atttaattct cttatttcac
    26101 tcttatcaac agtaacagta actccaccta aagcatcaac tatatccata aaagagaaaa
    26161 agtcaactac ggcgtagttt tgtatatcaa gttggaagtt ttcttctata gtttctatta
    26221 ataagttagc ttgtccatat acgtaggcat gtgttaattt ttgttctcca cgtcctggta
    26281 tattaacata agtatctcta tttaatgaag ttagcttaag acttttattt ttattatcaa
    26341 tagtaagtat catcatggca tcagaacgag aaacttcttc tcctggtctt gcatctgtac
    26401 ctaacaataa tatgtttgtg atattttctt catttttata gtcattacta ctaagcgcct
    26461 ctgtatttat actatcatct tgtatagttt ttaatttagt aaaaacatat ccatatatac
    26521 taacaggaaa tgctataact aaaagggcta gaaatataac gaactttttg agtcctgaca
    26581 ataatatccc ctactttcta aattttttaa ttacacatag ttaattatat taaaaatttg
    26641 ttacataagc aataaaaaac acaataaatt agcataagtt tgtcataata taattatttt
    26701 tatagcattt tatagaagaa agtgtgtagt tattattgat tttattggaa tataattgta
    26761 tgaagactta aatttttata aactgatgtg tatattgaaa aaaatatttt cctgaatgta
    26821 gttatagcat cttatgaaag gtgcaaattg taatttaaaa tttttagtgt ataataagaa
    26881 ttgaaaattc aaaccgataa aaattaataa aaaataatta taaattaata atttggggga
    26941 ggaaatgtat gataaaatta atagcaacag atttagatgg aactttgtta gatgaaaaga
    27001 gcgaaataaa tccagagttt tataaagtat ttaaaaaatt aagagagaga gggataatgt
    27061 tttctgctgc tagtggcagg cagtatcaaa atcttataaa aaaatttgaa gatataaaag
    27121 atgatatgat gtttatatca gaaaatggaa cactagtagt atataaagga aaagaaatat
    27181 tatcaaatcc tttaaataaa gaattagtaa atgaaatcat agagacaaca agaagtataa
    27241 aagggaaaaa aattgtaatg agtgggaaaa aatacgctta tatagaaagc aaagatgaag
    27301 cgtttataca agaggttagt acttattatg caaagtttaa aattgtagaa gatttgacga
    27361 aagtagaagg agacatattg aagatagctg tatttgactt caaaggtgca gaacataata
    27421 ataatatcta ctttgaaaag ttttctgata gagctcaagt atgtatttct ggagtggagt
    27481 ggcttgattt aactgcaaaa ggtgcaaata aagggagtgc cataaaaaaa gtacaaaaaa
    27541 tgttagatat aaaatatgaa gaaactatgg tatttggtga ccagttaaat gatgtggaaa
    27601 tgatgaaaag tgcctatcat agttatgcca tggaaaatgc aaatgaacat ttgaaacaaa
    27661 ttgctagatt tagagcaaaa agaaatactg aaaatggcgt tgtagataag ataaaagagg
    27721 ttataaaaat tggatagtca tatgtataga tgaaaaagat tattttgaag aaatcaaaaa
    27781 aatatcaatg taattttgat aaataagttt atttatgcga aaattacatt gatatttaat
    27841 aaacatcaat aatagatatt tattttttta tgatattcag tattttgttt tctatttgag
    27901 ttgcattttc agcagaaatt aaataaacat atctacctgc cttctcaatt atagtattat
    27961 ttgctatttc agaattgatt ttttctccat gaccttctcc aaaaggtgct tgtatcatat
    28021 cttttttata attttctaga gttttataga ttttatctac ctcgtcagtt tttataacga
    28081 taatatcttc tagagataat ttttcagaag aattaattac aaaaccttga attatgtctt
    28141 cctctacatc attaaaatag ttaaaatcct ttgcatcaaa gatttttgat tcctttataa
    28201 gtaaatcaga agattttaat gcttttttta tttttgatgt agaaacgttt ttgtaatcac
    28261 cacttgaaga acaactaacc attcctaatg ataagattat cgaaaaaaac aatattaaaa
    28321 tttttttcat gataaacctc caagtttttt aaactctgtc ttaaattagt ttactacata
    28381 attatataaa aataaatgta tttaatgtta cagttttgat taataatgta atattttgat
    28441 aataatacct attgagaggt gattagaaat gagaatacca aaacatgtag gaattatacc
    28501 ggatggaaat agaaggtggg caagtcaaaa tggtatgaca aaagataaag gatatgaaag
    28561 tggaatagac cctggactag agtcttatag attatgtaga gatttaggct gtgaagaggt
    28621 gactttttat ggatttacaa ctgataatac aagacgtcca tcagtgcaga caaaagcttt
    28681 tacaaaagca tgtattgatg ctgcaaatat attaatagat gaaggtgctg ctttattagt
    28741 tgtaggaaat acaaaatcgc caatgtttcc agaagaatta ttaccatata ctaatagaat
    28801 taaagccaaa gaaggtcaaa taaaagcaaa tcttctggta aattatggtt ggtattggga
    28861 cttaaataat atatcaggag tagaaaatgt aaataaaaat aatatacagg attacataca
    28921 gtcatttgat gtatccagac tagacttgat aatcagatgg ggtggaagaa ggagattaag
    28981 tggtttcctt cctgtacaat caatttatgc agatttttat gttatagata attattggcc
    29041 agattttaag agtgacgata taaaggacgc atttagttgg tatgatacac aagatgtcac
    29101 tttaggtgga taattaaaaa tattctgatt taaggttgta gagtgtttta aattattgaa
    29161 aaaaaaactt cttgatggta aaataacact aataatatgt aaaagtgtaa aaatttatac
    29221 caagaagggt gaagaaatgt caaaaggcaa taataacaat aattcaagaa acaaatctaa
    29281 aaagaccagt catctgaata gaaaaaagcg aaaattaaat aagaaaaagt tagcagtgtt
    29341 gatttgcttt acagttttat ttttatttat tgcatttaag gctactcaag gtgtagtagc
    29401 tttggtaaaa agtatggata aaagtaataa aactaatcaa caacaaaatg ttaactcaga
    29461 acaatttgac cttggtaatg aagaggaaaa taaaaagaaa aaatatactg tatttataga
    29521 cccaggtcat ggaggcaatg ataaaggaac tgaaagcaag accagtaata gatatgaaaa
    29581 agacctaaat ctacaaattg caaaaaaatt agcaaataaa ttatctaaac aaaaggatat
    29641 tcaagtagta gtatccagaa ctgatgatac atatatatca ttaaaggata gagctatctt
    29701 agcaaataat agttctgctg atgtgcttgt ttctattcat ttaaatgcag agaaaaatgg
    29761 taatacagca acaggtatag aaacttggta taggaataaa gctacagatg gttcaaaaga
    29821 acttgcacag acagtacaaa gtactatagt atcctatgtt aaagttagag ataggggaat
    29881 agttgaaaat aactttgaag tacttagaga atcaaatatg cctgctatat taatagagtg
    29941 tggtttttta acaacacctt cagaggaaca aaaaataata aatgaaaaat atcaagacca
    30001 acttgcggaa ggaattgttc aaggtgtact ttcataccta gattctaaag ggaataagta
    30061 aattaacttt actttaatgt gaggataaat ttaaaagttt aactgtgtaa attgtattaa
    30121 ctttatttcg taatgttgga aatattgttt gaatttagaa actatgaaat tagaaattat
    30181 tttatctata tctaatttca tagttttttt tgcaaaaaat ttatagttat aaaattttaa
    30241 aaaataaatt tagtataatg taatgtagtt atttatatgt gattttaact tgcattgatt
    30301 tgctatcaat tgtgctttat aattagtata tataaagttt aactgtaaga taatttaaaa
    30361 aataggggaa tttatatgaa taaaaatagc atgacaagaa tttacagttt aaataaaata
    30421 atttttatta taattggaat tttaggaata gttttactca caagacatat tgaggtagat
    30481 attaaagttt taattttaat tttattaacc ttgtttagta taaatgtatt tacttcatat
    30541 cttaaaatta agttgtatga ggataaaatt aatttaggat tgataaataa ttcagataag
    30601 tttataaata ttactaaaga tgagaacttc ctaaaacatg ttcaaaatta tattatcagt
    30661 aatgaaaaag aaaactgtgt aatggcttgt tttgatttat gtagactcaa acttataaat
    30721 gatatatatg gttatgagct aggggatgaa gtgttaaata atattttaag taacttaaaa
    30781 aattattttg gaaaagaagc tatttatgga aagttaaaaa gtgatgtttt tgtattaata
    30841 ataaagcttg aaaataggga acagaagatt ccttatttag taaatcttat taagaataaa
    30901 attgtgatac taagtcagat tgacagtttt aaaatggata taaatattga ggcttctatt
    30961 ggaatttata aatttaacaa taatgaaatt gatataaaaa aagctataga taatgctgat
    31021 atggcaaggc ttaaatcaaa aggactaaag cacatagagt atgtagaatt tgataatgct
    31081 atggaagaag aaatacaatc aattatgaaa atagagagag atttattctt ggctattaaa
    31141 aataaagagt ttgtaattca ctatcaacct aaagttgatt caagtacagg taacattata
    31201 ggttcagagg cattgataag atggttgcac ccatcattag gcatggttgg accaaataag
    31261 tttataccta tagctgaaaa aaatggtctg ataaacaata ttggtagatg gctaattcaa
    31321 gaagttttta ttaccattaa caagtggatt tcagaaggta taaatgtctt accagtctca
    31381 ataaatcttt ctagagtaga actatataaa aatgatttag ttgatttttt taaactgatg
    31441 tttaatacat ataatattcc aaaagaactt atagaattag aaattacaga aacgacagca
    31501 ctaagagatg taaaatttat aagtgaaagg ctttatgaga ttaaatcttt aggtatgaat
    31561 atatcattag atgattttgg agtaggtaat tcaaatttta tcaaccttaa ggggatacca
    31621 ctagatatta taaaaattga taggtcactt atattggata tagttacaaa tacaaaaaca
    31681 aagtttatgg tgaaagcaat tgttaacctt tcacatgatt taaacgtaac tgttatatgt
    31741 gaaggggtag aggatatgca tcaggtcaaa gtcttaagtg aactgggatg taatttcata
    31801 caaggttatg tattttttaa acctttggat gagatgaatt ataaaaaact tcttactgat
    31861 ggaagttata taaatctgaa agatactctt ttagataaat gcatgacagt tgaggaggag
    31921 taaggatgat ttcagaagat gtagattatt caataagaat cataagagct atatttaata
    31981 atggagaaga taaaccaata gatgctaaaa tgatattaaa aagtgaagat ataccaatac
    32041 taacactata cagactgctt agaaagcttt gtgcaaacaa tattcttact tttaacaaag
    32101 aagatggcaa gacatacatg ttaaatgtgt cattggatac aataagtcta agaactattg
    32161 tagaagtaat tgatggaaaa atatatataa ataaatgtac gagatatgta tctaattgca
    32221 gtaattgctt aaaaggttgt aaagtaaatc gtgaattgct agaaatagaa aaagaaattt
    32281 ataaactttt atcgagaaaa tctataagac aaatactaga ataaaaaatt ttcagctatg
    32341 ataataattg gaggttttcg gttatggatg atatatctca agataatttt ctactgtcta
    32401 aagagtatga gaatagctta gatgtagata ctaaaaaagc aagtggaata tattatactc
    32461 ctaaaataat tgtagattat attgtgaaaa aaactttaaa aaatcacgat ataattaaaa
    32521 atccatatcc acgaatactt gatatttcct gtgggtgtgg aaattttctt ttagaagtat
    32581 atgatatttt atatgactta tttgaggaaa atatatatga attgaaaaag aagtatgatg
    32641 aaaattattg gactgttgat aacatacacc gtcatatatt aaactattgt atatatggtg
    32701 ctgatattga tgaaaaagct ataagtatat taaaagatag cttaacaaat aaaaaggtag
    32761 taaatgattt agatgaatct gatataaaga ttaatctatt ttgttgtgat agtcttaaaa
    32821 agaaatggcg atataagttt gattacatag tgggtaatcc accctatatt ggtcataaaa
    32881 aacttgaaaa gaaatataaa aaatttctcc tagaaaaata tagtgaagtt tataaggata
    32941 aagctgactt atatttttgt ttttataaaa agattataga tattttaaag caaggaggga
    33001 ttggcagtgt tataactcca agatattttt tagaaagtct atcaggtaaa gatttaagag
    33061 aatatattaa atcaaatgtc aatgttcaag aaatagtgga ttttttaggt gcaaatatat
    33121 ttaaaaatat aggggtatct agttgtattc taacttttga taagaaaaaa acaaaagaga
    33181 catatataga tgtatttaaa atcaaaaatg aggatatatg tataaataaa tttgaaacat
    33241 tggaagaact tctaaagagt agcaaatttg aacattttaa tataaatcag agattgctat
    33301 ctgacgaatg gatacttgta aataaagatg atgaaacttt ttataataag atacaagaaa
    33361 aatgtaaata tagcttggaa gatatagcaa taagttttca aggaataatt acagggtgtg
    33421 ataaagcgtt tattttaagt aaagatgatg taaagttgaa ccttgtagat gataaatttt
    33481 taaaatgttg gataaaaagt aagaatataa ataaatatat agtagataaa agtgaatata
    33541 ggctaatata ctcaaatgat atagataatg agaatacaaa taaaaggata ctagatgaaa
    33601 ttatagggct atataaaaca aaattagaaa acagaagaga atgtaaaagt ggaataagga
    33661 aatggtatga acttcaatgg ggtagagaaa agcttttctt tgaaagaaaa aagataatgt
    33721 atccttataa atcaaatgaa aatagatttg ctatagatta tgataacaat ttttcaagtg
    33781 cagatgtata ttcttttttt ataaaagaag agtatttaga taaattttca tatgaatatc
    33841 tagttggaat tttaaattcc agtgtttatg ataaatactt taaaataact gctaaaaaaa
    33901 tgagtaaaaa tatatatgat tactatccta ataaggttat gaagataagg atttttaggg
    33961 ataataatta tgaagagata gagaatttat caaagcaaat aatatcaatt ttattaaata
    34021 agtctataga taaaggaaaa gtagaaaaat tgcagataaa aatggataac ttgataatgg
    34081 attctttagg tatataagca gttgtaagta ttaaaaaatt ataatctttt aattgtttat
    34141 ttaaatttag aaataaaaag ttagccatat aaaaaatatt aaaaatatat acttttcaat
    34201 atttttttga taaaataaga atgaatttgt gcaattttat ttttctccaa taactaaaaa
    34261 tagttttttg aattaatatt tgcttaagaa taaaaatcag aaacgttttt gatatagtag
    34321 gtgataatat gaaaggatta gttttagaag gtggaggaac aaaaggagcc taccaaatag
    34381 gtgcatataa agctttgaga gagcttggta tagagtttca aggagtaact ggcacatcaa
    34441 ttggtgcttt aaatggagca tatatagttc aaaatgatat tgaagtaatg gaagatattt
    34501 ggttaaatta tgactatact cattttatga atattgatag agaaacctat gagaggttta
    34561 aaaatgtaga tttcactact aaaaatctca atgcagtgtt tgagcttata aataaagcta
    34621 gaaaaaatga aggtatagat ataagcccat taagacaact aatggagaca acattaaatg
    34681 aagacataat aaggaaatca aaaaaagact ttggacttgt tacggtctgg tgggataaaa
    34741 aaattaatcc atatccattg tatatcgaag atatacctaa aggaagattg attgattatt
    34801 taattgctag ttccagtttg cctatttttc aaacgaacat gatggatgat aagttgtatc
    34861 ttgatggaat gttttgtgat aacatgccaa taggactctt ggaagacaaa ggttatgaag
    34921 atgttgttgt aattaggttg attgatgatt ttattgggaa aatgaatcta aatcgacatc
    34981 aaaatataaa tataaaaact ataataccat cagaatatct aggaggttct cttaataaag
    35041 atagagataa tgtagaaaaa aacatccgac taggttactt agatactatg aaagcatatg
    35101 aaagatgcac tggaattaag tattattttg atgtagagta taaatataat gaagaatatt
    35161 gttttgataa atttagaagt atgagcaatg aaacaataca atatatctgt aatttattga
    35221 atataaaaag agatgcttca cttagaaccg ttatggaaag tgtaatacca aagcttggtg
    35281 aggtgcttgg attgccaaag gatttttcat ataaagattt gttttactgt atatatgaaa
    35341 agaaacttga agaaaataat ataaacagga taaaattata tgattttaac aaggttatag
    35401 atgttgtaaa tacaaatatt gattctaata gaaatttagc ttctaatttt gaagttagac
    35461 ctaaaattag tattaaaaag aacaaaaaca caaaattatt gacaaattgt attataaaag
    35521 acataaaaaa tcaaagttaa ataaaaaaca aaaaaaaatt tgtaattata ctcgaaaaaa
    35581 gtgtatatta gtagtataat atttttgtag cactagtggg aacaaaaaat gaccatagga
    35641 caaaaaagta ccacttagta ccattaaagt aaaaaacagg aaaacaattt taaaaaatat
    35701 aaaatgtaaa gtttatagga ggatttaaaa aaatggaaaa agtagttagt atcaaaaatg
    35761 caagtggatt acatgctaga ccagcaggaa tgtttgttaa gaaggcagct gaatttaaat
    35821 caacagtaga ggttgtagca aaagacaaaa ctgtaaatgc aaaatcaata atgggaataa
    35881 tgagtttagg tttagctcaa ggagaagaat taaagttagt tgtaaatgga gaagatgaag
    35941 aagtagcttt agctgcaatg gttgaattag ttgaaagtgg atttggagaa tagatataat
    36001 aattttttaa aaatttgata tttagaatct aatattactt aaagtaaagt aacagagaag
    36061 tattaaacat atacagacca acatttgtag atatttaatt tctttgttac tttcatgttt
    36121 atttaatcag aagattaaga ctattgttaa ttgggtataa aaatataaat attttagaaa
    36181 atgaaataag atatttttaa tcataaattc agagtaaaaa tacagtaaca aatagtttat
    36241 aaaattttat aaaaaattat aagtaaataa aactataaaa atgtaaatta tttatataaa
    36301 tttataaagt ttatgtgcta gatgatattt tttaggaggt agggttatgg cttacaaagg
    36361 aataggtgct tctcctggtg ttgctttagg gaaagcgtta gtagttgaac atagtgaatt
    36421 agtaattgaa aaaaaatcta tagataatgt tgaagctgaa attgctaaat tagaagatgc
    36481 agttgcagtt tctaaagaag aattagtaaa agttaaggaa aaggcttctg aagaattagg
    36541 agcagaggaa gcagaaatat ttgaagcaca tttattagtt ttagaagacc cagagttaat
    36601 tggttctgca atagataaaa ttaaaactga aagtgtaaat gcagagtatg ctttaaatga
    36661 aataaaagag atgtttgtta gcatgtttga gtctatggac aatgagtaca tgaaagaaag
    36721 agcggcagat ataaaagatg ttacaaatag aatacttaga catatattag gaattaaagt
    36781 tgttgattta tctgctttaa gcgaagaagt tgtattaata gcacatgatt taactccatc
    36841 agacacagca actatgaata aaaaaatggt tttaggattt ttaactgata taggtggaag
    36901 aacttctcat actgctatca tgtctagaac tttagaaata gctgcaatcg ttggattaaa
    36961 tgatataact tcaaaagtta aggatggaga ttttgtggtt ttcaatggag acacaggtga
    37021 agtaatcgtg aatcctgatg aagagactat aaataaatat actgaattaa aagctaagta
    37081 tgaagatgag agaaaagcat tacagctatt aaaaggaaaa ccatctgtaa ctttagacgg
    37141 aaaacatgtg gaattagctg gtaacatagg aacacctaac gatatagaag gtctaataaa
    37201 gaatgatgct gaaggtgttg gtctttatag aacagaattt ttatacatgg atagagattc
    37261 tttcccaaca gaagaaatac aatatgaagc atacaaagct gtattagaag gaatggatgg
    37321 aaagcctata gttataagaa cattggatat aggtggagat aaagaattaa gttatttaag
    37381 tatggaacct gaaatgaatc cattcttagg ttacagagca ataagacttt gcctagatag
    37441 aaaagatata tttaagactc aattgagagc tttatataga gctagtgttc atggaagatt
    37501 aagaatcatg ttcccaatga tttcatcttt agaagaattg ttacaagcta aagaagttgt
    37561 aaaagaagtt ttagcagaac ttgattctga aggtgtggct tatgctaaag atgtagaaat
    37621 tggtatgatg atagaagttc catctgctgc tgtgatatct gatgtattgg ctaaacacgt
    37681 agatttcttc tctataggaa ctaatgattt aattcaatac acttgtgcag ttgatagaat
    37741 gaatcaaaag ataagttatc tttacaatca atttaatcca gctgttttaa gacttataaa
    37801 gactgttata gacaatgcac acaaagaagg aaaatgggca ggtatgtgtg gagaatctgc
    37861 tggagaccaa aaaatgatac caatactttt aggtatggga ttagacgagt tctctatgtc
    37921 tccaatatca atacttcctg ctagaaagtt aataacttca gttaaagagt cagatatgaa
    37981 aaaattagct gatgatgtac ttaatatggg tactgctgaa gaaataaaaa gctatataga
    38041 aaagactttt aatatataat taatgttata tagttactaa aattcatttt tctaaataac
    38101 aaaattatat tttacgaatt aaaaaggaga tgtttcaaaa taaaaatttg aagcatctct
    38161 tttttataaa agattactaa gaattactta atctttgtaa tagtcatttt gtgaaaaagc
    38221 aaaactgcat tgtgactata gtatatatgg atgttattat caataaaagt actattaaaa
    38281 tgaagattca ttctcaaatg atatcaaaag tagttgtgat ggagtaagat aatattttgt
    38341 gatttaatag taaaaattaa aaaaatatgg tattgaaaaa taattaaaag tatttaataa
    38401 tagaattagg gaagaataag tttataagta aaaataattg attactagtt aataaaataa
    38461 atgtgatatc caaataaatc ctaaatctaa tttgagtttt aatatagata gtctaaagtt
    38521 tgattattaa agatttaatt gtaagttgtt acagttgatg atattgatta gagattaaag
    38581 tttagagtag aaagttacct taaatttaaa aatgcaagat aacccaatct aaaaattata
    38641 atcactcgat aggtttaagg atttatttgt ttattataaa taggagggtg tctcaaaatg
    38701 aactttttag tttatgaggc actctctttt atatagaatt aaatatattt tattatttca
    38761 acaatgaaaa agaagcttat ctctattttg agacagcctc tttgtatact attattagtt
    38821 taatcaataa tataatttaa aattataata ttagttaaga tttcctgctt tattagtaaa
    38881 taattcttta atagcattgt ttctggaaac taaatcgtta tcagagttgt ttgttttttt
    38941 cataatcact gaataacgtt ttttatttat aaaaaatatt aaaatcttat catcatcaaa
    39001 attgtattct ttatatctgt caatagactc ataacctaga tttagaatgt ttttgtcttt
    39061 tatactatct acatctaaaa tatatgatgg gtcagccttt agtaatatat taattaaaca
    39121 tttttcttca ccagcacaga ataactccat cttacttgat atagatttag attgctctga
    39181 agttattttt gcaggaataa ggttgtcatt atcatctctt agaagataac catgtgtgtc
    39241 ttgttgatat actaaattaa cctttttctt aggaacacta atcattttat ctaaatgtac
    39301 ataatgatga ttttcaacaa aaccttcatt taatatttca acaaagttat taattttacc
    39361 taggcaaaaa gattctatag attctttaca gaatttattt gtaaatggta ttatgtttac
    39421 gttttcctcg tctgtattcc atgctatagc ataatccaac gaatatactt cttcctctat
    39481 atctgcaaaa ttatattgta ctatgtttcc tttcaaaatt actcgacctc catcttataa
    39541 tata
//
LOCUS       DAEORM030000035        39127 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.035, whole genome shotgun sequence.
ACCESSION   DAEORM030000035 DAEORM030000000
VERSION     DAEORM030000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 39127)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39127)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 39127)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39127
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.035"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            complement(660..836)
                     /locus_tag="KRH23_002317"
     CDS             complement(660..836)
                     /locus_tag="KRH23_002317"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5225595.1"
                     /translation="MFIGEIDKCTHILTAYISSSYDYCNFLDTQLDDFISEYGETVVE
                     TCLHQVLLLVSRYN"
     gene            1411..2433
                     /locus_tag="KRH23_002318"
     CDS             1411..2433
                     /locus_tag="KRH23_002318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5225596.1"
                     /translation="MVNWEIKKLAKSKSMFISLGILVLILMISIFITPVLETESYYID
                     KEKGRIEDTRSGIDVGNEKFQNKINVLKQFSNQTDTGEFSKKIELMSKKKLDNLSVNE
                     YKDISFWKVFNYRVTNSLINVGMLIIISIIISNIYVDEVVTSVKDIILSSKEKKKALK
                     SKIFVALLVPLVIYSVYLMGIFIITCMQQGVPVNGDLESFRIVDNVVALKTNLSITKY
                     VILNIGIELLMFEGWAMIAIFGSFISKSSISSISFFIFIISITKIMSVIHILPKKLLS
                     VVSNVNYYDLIFGFNKIIGNYLGDIMIFKVNIDIVNIAIGLLMAILIGAMSLCFLVIK
                     SDYISR"
     gene            2447..3334
                     /locus_tag="KRH23_002319"
     CDS             2447..3334
                     /locus_tag="KRH23_002319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHS5225597.1"
                     /translation="MNKLEIENLSKIYGKKVANDKITVTLENGVYGLLGPNGAGKSTL
                     MKQITTLIKPDEGQILYNGEDIFKMDADYRNILGYLPQEFGVYKNFTAKEFLQYIGAL
                     KGLRGKYLNSKIGELLDLVGLYDVRNKSIGKFSGGMKRRVGIAQVLLNDPKIIVLDEP
                     TAGLDPQERARFRNLIAKMSRDKIIILSTHIISDIESVAKETIMIKDGKLLMKGTHKD
                     ILSHMENKVYNVQVKNECEVDDIQSKYKVVSIQSDINSIVLRIVSEDIPSEDNIQPVQ
                     AKFEDVYMFYFDLEDAREV"
     gene            3340..4113
                     /locus_tag="KRH23_002320"
     CDS             3340..4113
                     /locus_tag="KRH23_002320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHS5225598.1"
                     /translation="MMYLVKAEMIKILKSKSVWIIWLFLIFFGFFLIRKFDVLDTYAD
                     IFYKIEGSIPLIGFIMFIITSGNYIKEYDSNMTGLINTTKKGKKSVVLSKLVANGLIL
                     SIINISFILLVGIRGFSFFDFKNLNESIHNLWYFGNSNLNLTVIQMYIIVILTTIFAS
                     FIFAQIGLTLSSIFKSAVIPFILGGLIMAIPYFSVGFIPDKAIKFMSVTPNWIMMSQQ
                     MVKYNVPIILIVFSIVISIILMIVLTKITYENFTSSKRF"
     gene            4225..4443
                     /locus_tag="KRH23_002321"
     CDS             4225..4443
                     /locus_tag="KRH23_002321"
                     /inference="COORDINATES: protein motif:HMM:NF012301.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HHS5225599.1"
                     /translation="MENRVLIIDDEVEILKLLETVLKKEGLNNIYTAKTKKEGLELFK
                     SINPDLIVLDIMLPDGEGLFVQQKVTKI"
     gene            complement(4430..5803)
                     /locus_tag="KRH23_002322"
     CDS             complement(4430..5803)
                     /locus_tag="KRH23_002322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HHS5225600.1"
                     /translation="MDKIKRVALYIRVSTEEQVLHGDSIRTQTEALEQYSKDNNFIIV
                     DKYIDEGYSATNLKRPNLKRMIEDVKNNKIDLVMITKIDRLSRGVKNYYKIMETLEKH
                     KCDWKTILEDYDSSTAAGRLHINIMLSVAENEAAQTSERIKFVFQDKLKRGEVITGSV
                     PFGYKIKDKHLVIKEDEASIVREAFDAYQDFSSLAKTIQHINTKFSTKYMFKWMPKML
                     KNKIYIGIYEKGDLVVENYCEPIISREQFNFVQTLLKKNIRFSENKFKMNYLFSGMIV
                     CGSCGRKMGGVHSRGGANRHYLYYRCPLSFATKLCDNKPYLNEKKVEAFLLENVKKEL
                     QKTILEHESNNKKRQKKNNNKNLRNKLEKQIEKLQDLYFDDLINKDTYKFKYKKLNDD
                     LSELNKAENEAESVEKDLKSMKIFLDTNFEDNYYDMNYSEKRTLWTSAIDRIEVQKNG
                     ELVIKFL"
     gene            complement(5868..6272)
                     /locus_tag="KRH23_002323"
     CDS             complement(5868..6272)
                     /locus_tag="KRH23_002323"
                     /inference="COORDINATES: protein motif:HMM:NF027249.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HHS5225601.1"
                     /translation="MYKNEYIFPAVIAKHDKGDYEVNFYDFSNIITCGENLEKAFLMA
                     EDALKLELFDLYSDGLEIPKPTQLNNISTKENQTAILVKVNLKETIKEYDSKSIKKTL
                     SIPSWLNKEAEKNNINFSQLLQEALKNKLNIN"
     gene            complement(6307..6738)
                     /locus_tag="KRH23_002324"
     CDS             complement(6307..6738)
                     /locus_tag="KRH23_002324"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5225602.1"
                     /translation="MDFTGVIRNSFNNVVLCGEYAGSLLGITNFPDNHIIAQSAFIDK
                     EIDTDYFTVYPVKNLDLSYVEEVRKGVWITNPARTICDMIRYDSEYSFIQEALDYYIF
                     YNENEKEHYNEVLNVARYYNIEQKVLDAISFAKSHDYYEEN"
     gene            complement(6720..7541)
                     /locus_tag="KRH23_002325"
     CDS             complement(6720..7541)
                     /locus_tag="KRH23_002325"
                     /inference="COORDINATES: protein motif:HMM:NF020419.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HHS5225603.1"
                     /translation="MINNKWSNSNNFHDNNSTLDYIEDFIYCMSHSNSFNDMIFKGGI
                     TLLCAFKKYNYGNRRLTKDIDIHGTDYNKWLNFKKDIIACSQYSRFKVIYKVIKEIAT
                     SEATKNESVTIGVYRAAELITRFSIDVNFKWSTLDSEKYSLGGLVTINGYTPELILVD
                     KIHACESKQINRRLKDLFDIYSLSYLKGYNSNDLVRLYIDKYKNIPEKMYMFQLENFN
                     TLEHGYNRLRGIESKPEFATVYKRVSNFIVPIHTFIASKSNKNYVWRNDRWTLQE"
     gene            complement(7647..8171)
                     /locus_tag="KRH23_002326"
     CDS             complement(7647..8171)
                     /locus_tag="KRH23_002326"
                     /inference="COORDINATES: protein motif:HMM:NF017885.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HHS5225604.1"
                     /translation="MISNSDDFKVYTYIEFSRVIKKDIDFIIEKYDCQGFAFWSEKDS
                     KHIICYNSDYSFYSVHWTLTHEIAHIVLGHTKKTSIVKLNSRNKLLELEAEIFTQYLL
                     CPDIILLYCNITNIYEIMYICGVDKKTALIQSHYIKKIKLSNCITNLENLIKKQFYKF
                     IKNYLKHRKKDTYF"
     gene            complement(8253..8828)
                     /locus_tag="KRH23_002327"
     CDS             complement(8253..8828)
                     /locus_tag="KRH23_002327"
                     /inference="COORDINATES: protein motif:HMM:NF024252.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHS5225605.1"
                     /translation="MNERIAILRSYLNMNQRDFSNKIKVSQSTLAMFETGQRIPKNIH
                     ISQICSEFNVNEDWIRFGSGDMFIKTDINERLKLIRLYFNLSQKNFGSRLTIAQNYLS
                     NIEKGYRNVTDKIIKITCFEFNINEEWLRTGIGNMFTKQDDILQKVAIEYNLEESDIE
                     IFRNYLKLSKEERKVIKKYFFSFSDKTINED"
     gene            complement(8856..9353)
                     /locus_tag="KRH23_002328"
     CDS             complement(8856..9353)
                     /locus_tag="KRH23_002328"
                     /inference="COORDINATES: protein motif:HMM:NF024252.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHS5225606.1"
                     /translation="MNERLKQIRSHFGMSQAEFSKHILVGSSTLAMWEIGTRTPKDIH
                     ISKICSEFGISEEWFRNGIGEMFIENDNTIIFELSNKYNLDNLDVKILESYLKLSGEQ
                     RKAIKKYVYSLVDTILEDDELYQDYRSKYINENNSHMVARNGNPQNEEDLIKIYDNAD
                     NSLKK"
     gene            9485..9685
                     /locus_tag="KRH23_002329"
     CDS             9485..9685
                     /locus_tag="KRH23_002329"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5225607.1"
                     /translation="MNKVIDNKTKKMIEAEERVKNEFLSKKIDSDDLMKEIVKMPYEQ
                     KVKMFYIMKGANITNDSDVSVI"
     gene            9863..10063
                     /locus_tag="KRH23_002330"
     CDS             9863..10063
                     /locus_tag="KRH23_002330"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5225608.1"
                     /translation="MSKPYEKIETENKMNMDLFCKGYARAKEMMAKRLFDVDLEIKYT
                     YRKKTEEEMKAEKEKKLEKEVI"
     gene            10334..11116
                     /locus_tag="KRH23_002331"
     CDS             10334..11116
                     /locus_tag="KRH23_002331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009527719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rolling circle replication-associated protein"
                     /protein_id="HHS5225609.1"
                     /translation="MKSFIREKKIYCNDYLEIDIIPRADVQTKGKRGKREYISKPKQK
                     NLNDKNAKRYFTQSVNTNFTKNDLVVHSTYAPEFLPETLEEAEKEVRNYIRRIDYKRK
                     KEGLEPVKYMLITEFGEKKDGTKRVHHHIIINGGLDRDIIEKLWSKKQKGRKEGEKLG
                     WINTHRLQPNEYGLQNLCNYLMKDPKGKKRWSSSRNLKKPFQVCNDSRYSKRKVMDIV
                     RNDLDNRMFWEKQYKGYIFTECKATYNDITGVSLYIKMRRLK"
     gene            11126..11269
                     /locus_tag="KRH23_002332"
     CDS             11126..11269
                     /locus_tag="KRH23_002332"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5225610.1"
                     /translation="MYLRVCKCCKKEFETNLYSKTYCSYVCKNKFKNEKRKKEKKEGN
                     ENE"
     gene            11262..11576
                     /locus_tag="KRH23_002333"
     CDS             11262..11576
                     /locus_tag="KRH23_002333"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5225611.1"
                     /translation="MNKEIEAICIEVEKRICKICKYNNTCNVEKKNGRICSFFEEKSK
                     IEKLLEKSNFISAMDFRLKNISMKEVESYCKENNKKIEICGWGSGQVMIFTDKRKAKT
                     ND"
     gene            11569..12024
                     /locus_tag="KRH23_002334"
     CDS             11569..12024
                     /locus_tag="KRH23_002334"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5225612.1"
                     /translation="MTNKEKIKGFMLADLCQDESNKRREKDTYYAGKNHTFNYDLYPV
                     ITKDINRAKVYRTKKEAKRELETLNKKCIHNYFEIVSFKKYIKNMSNKEMLEFISMKE
                     NKAYKKYSKEICNICKSIKFNCESLYCEEAYSDWLKENAWGKKRGDKND"
     gene            12286..12888
                     /locus_tag="KRH23_002335"
     CDS             12286..12888
                     /locus_tag="KRH23_002335"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009527716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HHS5225613.1"
                     /translation="MDDKKLQQRYKNKVANAQGQHFENYINSACIIYRNDNRAEIDKT
                     PEPFRVLSKDKTGKFTGRFIANAQPDFKGALKTGMCICFEAKYTLKDNIKRSVLTNSQ
                     LETLDRYYHIGAITGVCIGIQDKFYFIPFLVWRNMKNCFGRQYVKQEDIKRFEIKFFN
                     GAVLFLDYITKDEKILNENYSLLRKKFENEIDDSIKKVRG"
     gene            12890..13342
                     /locus_tag="KRH23_002336"
     CDS             12890..13342
                     /locus_tag="KRH23_002336"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5225614.1"
                     /translation="MFLNLYTKKDFNEIKAEYEIAISRIEELKDKCSRKEKIISDLEN
                     KNAALHTEKMSLKIRYENEQNIKKGMEAGAEILREEIEKLKEENEILKKTIETFNNKI
                     KEIELKFKKTLNDKITRLEAIKARTKRFRKKKKIEKIIEELELKSFLE"
     gene            13356..13535
                     /locus_tag="KRH23_002337"
     CDS             13356..13535
                     /locus_tag="KRH23_002337"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5225615.1"
                     /translation="MLLANRDKIIQLASKIVELYNVEDLEATIKAIQYLEKVEINGVI
                     QEEEYNKLLKIIVGS"
     gene            13540..13965
                     /locus_tag="KRH23_002338"
     CDS             13540..13965
                     /locus_tag="KRH23_002338"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5225616.1"
                     /translation="MQKKVINHFIDCIKKSRQRMLIEKGDKYYLSDGICIFIIDKKEM
                     VLNPKMFLFNSEKAKKIVGDIKETGYQEVVLKYYIPVHGIVYHKYICEDFEIYLDEVF
                     VKVFDKFDKVEAIDSKSPVRISMKGHILGYLMPVTIKEN"
     gene            13990..14745
                     /locus_tag="KRH23_002339"
     CDS             13990..14745
                     /locus_tag="KRH23_002339"
                     /inference="COORDINATES: protein motif:HMM:NF018290.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HHS5225617.1"
                     /translation="MKIISILSFKGGTGKTITSANMADILSVVHKKRVLLIDADKQGN
                     LSQYFSKFEEKKGKGTAEMLLEDNANIHEYICKTENKNIDIITSNMYLYQADRMLFDS
                     DRDKFSILKRLLEKVKNEYDFCIIDNAPSVDIVTINSLVASDEVIITVRADNFSLKGI
                     KELLEQIENAKHVNKKIKFKGCIITHYQNNDVNNQFITLLQNICKVFETVIRLNKNVA
                     ESTFYQKTIMKYNKRCGATIDYKKLVNEYLNIE"
     gene            14787..15827
                     /locus_tag="KRH23_002340"
     CDS             14787..15827
                     /locus_tag="KRH23_002340"
                     /inference="COORDINATES: protein motif:HMM:NF014273.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HHS5225618.1"
                     /translation="MAFNMFEAISNSNNRKLENNNKNIKNKKTEIKNISVYDLVPSED
                     NFYSVEDIEDLKSSIEMFGIKQNLLVRENEDNKYTIIAGHRRRLAVLKLLEENKENEK
                     FEMMPCMVEKITGIRAKILLITTNSTARELTDFEKMKQAVEMRKLLEELRAEEDIKGK
                     TRDLVAKMLNTSAGQIARLENISKKLMPNFKNEFEKENINVSTAYELSRLEEAEQRSL
                     FEEYQGKGSLSIKDVTEKSKEKKSEISVSTTYKIEEDENEVEETEEIENVIDFPSTTI
                     EDEIEERKVSKTIFEILKDMKIRKFAEFVCSQCNVTGTFCDYAMECNDKNGKGSVDIC
                     IKWLKMEAQEME"
     gene            15785..16015
                     /locus_tag="KRH23_002341"
     CDS             15785..16015
                     /locus_tag="KRH23_002341"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5225619.1"
                     /translation="MHKMAKDGSTRNGVDIRHNKSGYLDNTAYEAIRKIDKEKQEANI
                     LIELIKKMAKVAGFEIIGRIELRNKKSRVIYK"
     gene            16039..16881
                     /locus_tag="KRH23_002342"
     CDS             16039..16881
                     /locus_tag="KRH23_002342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5225620.1"
                     /translation="MNLNFKSTKIPIYDIENSAGISYPRRTGTRDSNTHYKATKNKVI
                     FRVKKEDIFIRFLETGEKELNEKYYLYIEYLKEIILKEEVESFKKGFEKADIWAGKYL
                     NNFEYLNKLIWDIKEKRQFKMLEEEKVDTLEKAKNIKFPCFSKYSGEYIYNVMQTDLE
                     HCIAYYVGNLSNREFDFSNIGVSQLKYNQSPERTRSYNCIKYLLNEFYPHISRNLLAY
                     FKYINIDDAKRITFKNGKYKDKTVYYVFKENRSYIEWFLQNTKKTIYNIRLITAITLI
                     REQE"
     gene            16897..17469
                     /locus_tag="KRH23_002343"
     CDS             16897..17469
                     /locus_tag="KRH23_002343"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5225621.1"
                     /translation="MLKGIGEGTENINIDMLIEKVTNIAAEKAISTYENRRKEELKYS
                     YDRKLRNTKLLLKHYKDFKRHVNNSIFKVSNVSENAIEILEELINTKITENLFVESIS
                     NSVSRTNIIISHINTMINIYEAYSKQHGELEERKYRIIYKRFIDEKQWSIKEIATSEN
                     IDNRTVYRDINLACGKISVFLFGIDGVNKF"
     gene            17770..18096
                     /locus_tag="KRH23_002344"
     CDS             17770..18096
                     /locus_tag="KRH23_002344"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5225622.1"
                     /translation="MSKVICDKCNHSFKVNLKDIKTYFIDDIEIKYFKCRKCKERYII
                     SFEDDKLKEMKKNYNEMLNEEKEYRANGLDYKETPLWLMIDSFNNLVEYQNKLKVKVY
                     GETICQ"
     gene            18093..18518
                     /locus_tag="KRH23_002345"
     CDS             18093..18518
                     /locus_tag="KRH23_002345"
                     /inference="COORDINATES: protein motif:HMM:NF013964.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HHS5225623.1"
                     /translation="MKRICKCGKKIDYDKKMCEECYKRYNKTNKKIYDYKKYNKKYNS
                     EKRNNQEFYGSKNWRIAKDKARVRDKNLCRLCYDNKTIKKADLVHHIEEVKKCKDKIY
                     DTNNLICLCERCHREVHLLYKSKASIIKEKLKDLVEEGF"
     gene            18687..19112
                     /locus_tag="KRH23_002346"
     CDS             18687..19112
                     /locus_tag="KRH23_002346"
                     /inference="COORDINATES: protein motif:HMM:NF016975.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P27 family phage terminase small subunit"
                     /protein_id="HHS5225624.1"
                     /translation="MENSRGEGASLKTYEIIPKPPAILSKLGKEKYTEIAKSLVDEEK
                     WKVGDEIALTALCVNYQRWMQAEKAIKTNKDLCFETETGYRQQIPEISIANNCMKMML
                     TFIKEFALTPRERVKLKELVLNPTEVENIDKELDDMIQK"
     gene            19122..20801
                     /locus_tag="KRH23_002347"
     CDS             19122..20801
                     /locus_tag="KRH23_002347"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: protein motif:HMM:NF042863.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0140657 - ATP-dependent activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HHS5225625.1"
                     /translation="MNEKLKEIIDKQLTWNLDDAIGELKNKWDNEKYYYDVEEAKKFL
                     TFASKLELDKGKKGKKIKLIKFQFEICTSIICVKRRSDNLRRFREAHINIPRKNSKSF
                     LIALIASYLYFCKNEFGSETIITANSRDQASLLFNTIHHMVKTNKTLKKYVNILESRK
                     YMFKKNMNAYLRVLSSDAGTADSYAGYVCIIDEIHEAKNRQLYDKLKTGAGIWEEPLM
                     LTITTASSGDNPENLEFELYSYSKELMKGEFEDDSFFYAIYEAEEKCELLDEEQWFKA
                     NPALGTFRSYEELKNLAIRATRLKTQEAAFRRLYLNQHVALDGEGAINMELWEKAERE
                     INLEELRNMKTWDGMDMGSTQDITAYVMVFYDEDTNKYIIYPFLFTPKDTIEERSERD
                     DIRYDILVQEKELIALEGRSINYQYMHDYLEETKIKYELETQEIGFDRWGSIGIRNKL
                     EEDYDVLPFGQGYSSMSPAVRDFENILLDERIIIAKNSLFRRMAKNVVAVMDDAGNIK
                     YSKKRSKYKIDGIIAMLMGISRAIFNNEGEQFSTQNNVDKFLNKVMGGEED"
     gene            20788..22041
                     /locus_tag="KRH23_002348"
     CDS             20788..22041
                     /locus_tag="KRH23_002348"
                     /inference="COORDINATES: protein motif:HMM:TIGR01537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HHS5225626.1"
                     /translation="MKKINAVNKIRKYIANKIDPTPKSVGDSDILTWLGIDETSKNIR
                     SEITYFTCLKILSEGIGKLSLKTYKRTEKGREAIELSDISRVLKVRPNEYTTPAIFWS
                     TIEQNRNHFGNAYVWCRWSGAKLIDLWIMQSDCVEIYVDNHGFFGKKNKVWYVYNDPK
                     SGERYIFQGKDVLHFKTSHTLDGITGLPVREILRDTLEGNLNSQQYMNKLYKQGLTGK
                     AILQYTGDLDKKAQRKLVSFYEEFSNGIDNTGKIIPVPIGMTLQPLNIKFTDVQFFEL
                     RKYSSLQIAGAFGIKPNHINDYEKSSYSNSEMQQLSFYVDTLQFILKQYEEETTFKLL
                     TNKQIEEGCFFKYNERAILRADTKTQMETLTAGVNNGIYTPNEAREFVDLPEKEGGDI
                     LITNGNYIPITEVGKQYEKGGVNNE"
     gene            22034..22741
                     /locus_tag="KRH23_002349"
     CDS             22034..22741
                     /locus_tag="KRH23_002349"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0046797 - viral procapsid maturation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="head maturation protease, ClpP-related"
                     /protein_id="HHS5225627.1"
                     /translation="MSKKNKDNLINILQIKNSTDKKAELYFYGDIVSSSWGAWEEEDQ
                     YPESIKNFLKGQEGKDLDIYINSGGGSVFAGMAIYNMLKRHTGFKTIKIDGIAGSIAS
                     IIALAGDKIIIPRNAFFMIHKAWGIVQGNSKKVIEYASLLEKIDKTALEIYKENLKNE
                     NDIEKIKQMIEEETWLTGEEAAKYFNFELSSEVDAVACSGDILDKYNKTPKVINNIKV
                     NDIEERKNNLLKRIERI"
     gene            22755..24101
                     /locus_tag="KRH23_002350"
     CDS             22755..24101
                     /locus_tag="KRH23_002350"
                     /inference="COORDINATES: protein motif:HMM:TIGR01554.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HHS5225628.1"
                     /translation="MKNKNKYNTNLNVYMSTDIREVKASIDENVEKIKNLIIENKLDE
                     AEKLTVDTEKLKKIYNGLLELEDEELDNIKNKINNSKATKIKNIEEKAKYDGNLFCKV
                     IANTLLKQKEKNEFSAAREQFEFTDSERMAISENIDEDGGYAVPEDISVKINRRLKDS
                     VDLSTLVDSEQVYTRSGQRTYEKRMKQTPLGKLSEYNSSTQTYGKIKDTDNPKLERIS
                     FNLIDFAGMITIPNDLLKFASKELENFIIDWIVDKVRVTRNMIILNGYKDDDGDEIGG
                     IFSDTTKFKKVDLKSTSTIKNFKKLKNVTLNSVFKKSSKWIVNQDGFNFLDSLEDKNG
                     RSYLQPDTKNETEYKFLGLPVIEINNETLETETIKSGSEGSETITNVSPIILGDLKEA
                     YKIFHDGKYQLATTNIGAGAFETNTNKARIINKLDGSVKDDEAIIIAKLTLPEELV"
     gene            24101..24376
                     /locus_tag="KRH23_002351"
     CDS             24101..24376
                     /locus_tag="KRH23_002351"
                     /inference="COORDINATES: protein motif:HMM:TIGR01560.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="head-tail connector protein"
                     /protein_id="HHS5225629.1"
                     /translation="MLDEIKAYLRIDSDDDDNWIEKTLIPAINLYFKNAGINIDAVRE
                     EELYKLAVEMMACHWYENRGVVGDTKGIDFGLKTIMLQLQFCYEEDK"
     gene            24379..24717
                     /locus_tag="KRH23_002352"
     CDS             24379..24717
                     /locus_tag="KRH23_002352"
                     /inference="COORDINATES: protein motif:HMM:NF017343.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HHS5225630.1"
                     /translation="MNVGELNRKITIQIREERKDENGFTINEWLDFKTVYSSIKNLYG
                     KEFLQAQALNSKASKKIKIRYIKELDNSINKDSSIEYRVVYKNIIYNILYIDNINEAN
                     KYMEIMLEGE"
     gene            24719..25105
                     /locus_tag="KRH23_002353"
     CDS             24719..25105
                     /locus_tag="KRH23_002353"
                     /inference="COORDINATES: protein motif:HMM:NF016754.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HHS5225631.1"
                     /translation="MGITFDFSKLQQKLNSMERKAGKELVDNAIDAGGRVLVEGMKEE
                     VRANVYDTGELYNSIGMGRKKGSGTKRSIEIGSQSNDRDVVARNFYNEYGTLRVVGKK
                     HNKRSFNKNKKKANEAIKKSIISDLK"
     gene            25115..25456
                     /locus_tag="KRH23_002354"
     CDS             25115..25456
                     /locus_tag="KRH23_002354"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5225632.1"
                     /translation="MNINKLIIETIESLDIDTFYIEASKGKDKYCIFSIYKENEEDIF
                     DNLHSSIKYYITVNYWFRNPIDAELYKEIKKKMKLNKFKIDGCRDLPKTGDYYGKNID
                     FIYKQREEITI"
     gene            25496..26074
                     /locus_tag="KRH23_002355"
     CDS             25496..26074
                     /locus_tag="KRH23_002355"
                     /inference="COORDINATES: protein motif:HMM:TIGR01603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="major tail protein"
                     /protein_id="HHS5225633.1"
                     /translation="MDAYTKKIVYGMDKIHVAKISEDGYVTPVAIVGAKEVEANFEIG
                     DKTIYADNKGIYNNKKISKGSGKLGVIGLTTDEKCLLGGTENMSGGYALADNVIPPNL
                     ALLFAQDKADGGSLLTVIYNVQFNPVSIAAVTTEDSIEETKTELEFTALVGKDGYWYY
                     TIDTTDTKVDADMISKFFTEVQLPKIKADSEI"
     gene            26097..26651
                     /locus_tag="KRH23_002356"
     CDS             26097..26651
                     /locus_tag="KRH23_002356"
                     /inference="COORDINATES: protein motif:HMM:TIGR01603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="major tail protein"
                     /protein_id="HHS5225634.1"
                     /translation="MGYEEKILFGLDNIRVCKMSNDSIPIKILGAISVEVEVKQQYKY
                     LYVRGRKRVKINGAIECTGKLRLLGLTSLEQNLIFGHIESEGVAVGENSNSPNLRLLF
                     SREKANGHKIFYCIYNVVFDLSSIDANTTKETMSEDVVEINFEGLKDDNTNLTYYSID
                     TETCDKNVIDNWFKKIQYPKEVKR"
     gene            26648..26977
                     /locus_tag="KRH23_002357"
     CDS             26648..26977
                     /locus_tag="KRH23_002357"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5225635.1"
                     /translation="MNGNKMEIKMNGVVYEAKLDMGALAEIQDFFRKKNDFLKLPEII
                     RGYSEENFMIINEIIIQSIQRCHKQLKRDEILDNMLLKDIGKIKAYAGELIINSLPKD
                     DKKKEKE"
     gene            27022..27171
                     /locus_tag="KRH23_002358"
     CDS             27022..27171
                     /locus_tag="KRH23_002358"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5225636.1"
                     /translation="MWYTVLQRREEFWDITPKKLFAQLDAHKKYNGVNEEVVKQETVD
                     TTEFM"
     gene            27184..33867
                     /locus_tag="KRH23_002359"
     CDS             27184..33867
                     /locus_tag="KRH23_002359"
                     /inference="COORDINATES: protein motif:HMM:TIGR01760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HHS5225637.1"
                     /translation="MSETIEKLAVELALEAGSFSKQISSINKEIKNLERDFKSAGNGT
                     KNFENSFVGLDAKIQKTARQIDLYNKKLISQKQEQDKLKSTLTEQKSKLDSLEATLGK
                     GSKEWQKQAQLVQQTSSKLNRLNSDVKQTESTINKLGTELNQSTRAFSNLGNKTQTIE
                     QKLANVNRQTTLTESEFNKLGAELNQSGTYFQRLGNEMQQLSAKIQSNKAMLSIYESE
                     IRKLNTSLTQNKQTHSQLKTEINQTRNALEQAKSKFGANSTEAQQLHAKLLQLKDAYN
                     KSEHEIEQSNAALDRYQAEINNTRADITRLSAQLRQMPFNTMGQSMVSAGQKIKGVGQ
                     SLGMYVTMPLTMLGVAASRAGVNFDTSMSKLQATAGIADKSSVSFQKLQEKAQDLGAR
                     TSFSASEAADGLTYLALAGWDVETSLSRIEPVLRAAEAGGMDLALCSDLVTDSMSSAG
                     IASKDFTKYLDITAQAQRKSNTSMQQMLEAYVVAGGMFKNLNMPLEKSGALLGVLANR
                     GTKGSEAGNAIISVFSNLITEAGQAGKALEKLKISLFDKKTGKQRDTIEVLKEMAQKL
                     GVTADGTSKLTEAEQAQYAAMVGGKTQYDSLMKMLAGVSDEYDDLENNLRNSKGSLME
                     VAKTMKDNLGGAITNMKSALEGAGIQAFKAMEPVLASLIEKITQLSNWFTNLSESSQQ
                     SIVKMAAMAAALAPILIAFGQLIIVGGNLTLIIGHIKAAMTATAGTSTSLLTKLGNLT
                     TKLFSLQGAFALLAVAGIGVAVKALHDYSVQDGKLYEQRKKNIESLEREKKGYQEAKE
                     KIGYIAKEYDTLKSKSKLSNEEAERLKELTKQIADLMPELVSGYDENGNPILSMKGSA
                     EELCLELDRAIEKKERLIGFDKQDNAKIAMEKQAGKRDKDGNKVVGKAADSLQTDIEK
                     VKTVQQKYNADMAKLEQEGAVLRGKIRNTEGKDREKYLLKYKNHLREKEKVTQDAQKN
                     NERDIEAAKKVAQEVEEGIFASTTMGSVFKSSKNNDAKKQFNELKGLLDFSGIKTDEQ
                     FAKAEISMSKLFKSASDGKINLEGVKKQIEDANTALSKDGDLSSYNTKMQELAKTIAT
                     ATGTKSSDWISLLTSLDKEFLRTTDSTDIFLKKFNRTRQELESGDSLAVAAQRQFDEL
                     NSAIEGLQITENKDVNVQTVIDFTNNQNIPEDIRKFTSSLIKKDANGNITNSEEVIKF
                     TADLLFELQQEKPDWNILQQEADKLFGKGKVKVTEDLEITAGEIDSSKIDKNNIEQQV
                     KDKFSKDKVTIKINTAIEKGEIDTSKIGLVDEIFNNINATKEVKTKFILENTDAINQA
                     KNYEEFLKNFKDKEYLAKLGIKVEGKEETKQANKEFEKNNGKTSTQNVKLEGAEQAKK
                     DTQELNKETDKVDGKVVETKVNNEQVEESVKDINQLVEMSKKVEDGKYKIDVQANTTD
                     AVRNLELLKNKMNEVIKSFAGNKKVVFSAETELASKNVTGLKKNISDYDKKNTNKTKK
                     TTFKTETALASKNVTGLKSNVSDYVSKYGNKTFTTTFKVVTNKVTTTSTSGTNNSGGT
                     DEQSEDGRKSIPINLKRVETPTRKVPIRSSVPLLRKTAETPINMGNMGDSLKYNVNLF
                     QELENRISAVNNELTLLDKKAEKATGKEKIKHLQKQNELYEEQQRLQLELQDKMLFKQ
                     TVTKSKLEGYGLQFNNEGNLKNAEEELLRREKKAAELEKKAKELSDRASNEKNEKRKE
                     ALEKQAEAAQKAYDKEKTSLDDVNKYIDEYIKTTLTDIPKCIEEWEELNKKKKENIDI
                     TEELNRQQKLFSKNSHIKELDMYKDLYSDEIDIIEEKINNASGSEKTDLIEEKIRLIE
                     KQKKVQQDLINTYKSAIKVYQTDLSKFGFQFDDKGTIKNLDDILNKYQDSEDLEKITK
                     LVDEYLTIQRDKLPDAVKDWEKLSTSIKNAYKEQLNIAKDIENQITDIYKKQLEERKK
                     LIDEELKKRTDALNKEKEAYNDARKEADYQNQEDEQLQKIKDIEKNLELAKRDTTLSG
                     QKKVQELIKQLKEEQKNLEKMVQDRIDEQVNDMFDKENDRLENEAEGAVKDLEEKFSD
                     SKIKELIKEALKSGLFEDIDGQVKNLQDVMLKFLDDYGDGLGITGELIKDELVKNLEV
                     ATDVAKQYAEIMENLNLGKGGRSINYPNVDYSSERYNPQQRSINNQNTQEINIEFNQP
                     LVVIQGDVSRNTIADLQKLSKDIKNSVVDEIIRKMKR"
     gene            33864..34646
                     /locus_tag="KRH23_002360"
     CDS             33864..34646
                     /locus_tag="KRH23_002360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail domain-containing protein"
                     /protein_id="HHS5225638.1"
                     /translation="MIKLFVSEHFMFDNISSSEKGVISVTQDSDVLNEYGFIYSEELE
                     IDNTYNNNPYYYSKSDKSTEDIYINLCRVDNMYNPIEWDDYTIEDIYSWLIKKDFKPF
                     VSDDNVELTYYLKVKKIVKKFNIDKKGLLEITFQPYTNYSYRKLKKAVTIKKNREVTV
                     TNYSNLDTNYAPILEIKNLSDEDITVENITIKSERLEIAGLKLNEKIIIDNLMYTVLD
                     ENKNNRFNLVNRKWIELKKGENTLKFTGNCEVIINAEYPIAR"
     gene            34650..36314
                     /locus_tag="KRH23_002361"
     CDS             34650..36314
                     /locus_tag="KRH23_002361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HHS5225639.1"
                     /translation="MKINLKELKRDYEIVLCKINKCAVGQINIRFIDTLSRSIDSMDE
                     IQFTIPKFIYDRNGLKNIRYVLYDEIKEERFICLDDREYFVIKEIEINDNKDKIVKAY
                     SAEIKLSKIDINIEDVAIQLFSDDKENGVISLNNYLKQETSWSIGHVDDVVAYEMNEH
                     GDKVEKLRIQESVSSNWHDFFIKDIKEEFSCVVQFDTYNKKVNLYDIDSFGDNIELVL
                     TYDNYIKSNKKTNSTNDIVTRLKLIGREEMDIISAVPTGYEYLENYSYFLENGEMSEG
                     LVNAMMTYEEMVAVRKKEWSKLVEIKNTKEAERLKKSNKWQMIIANIEICEKMIVSYK
                     NAKDDKNVALKQSELTKLKDEETILEVEIKRLEQEIKGLEDSIININILCKRETATDQ
                     DGHLIFSYELLEELKEFIYCDTFSNDSFLNVDDFVNAGKRELDLKCKPTTVYSIDVVN
                     FLRRILDTGFRQHFQGCLSLGDIIVLYNNVECYEEHVYFVGYTQDFKEDKLNIELSNK
                     KLKTDNTRTIADYLTKSRSTTNLLNKKKYLLNKQKYNRMNVPERVM"
     gene            36314..38257
                     /locus_tag="KRH23_002362"
     CDS             36314..38257
                     /locus_tag="KRH23_002362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0098024 - virus tail, fiber [Evidence
                     IEA];
                     GO_process: GO:0019062 - virion attachment to host cell
                     [Evidence IEA];
                     GO_process: GO:0046718 - symbiont entry into host cell
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber domain-containing protein"
                     /protein_id="HHS5225640.1"
                     /translation="MAITDNSYTNSYIRITGCLVNYDKELYQVQDDFTNKKYVYWNRE
                     NPYKFEFSNKMLDKGNTRFLIIINDNGVHTEYKNYSDIFSITFDGDSVKNIQKEIYAL
                     YENDKEFGDRFVAVEKDVDGISQTVGLIQEDTNHMKENISFIEQRADNINLFVKEVTK
                     KFNNSQEAIKLREEVNKTIIKLNEDLGLFSSNIVGYFEDDEITDIEKEQIYTQIELME
                     NDKANVYIQLQKIIDKCQSNNDNVSISAINSSKTALDNAHNNLKSIIDSVVVDSIVTN
                     SERVLVINCFSKYNLRINELKNTLDVIFLKEAGGSVSEEFAGINVKFDEVNLSVKKIN
                     SDIGEISSEIKLMNDEILLKVNEGDLSSMIEQRYNSVKIAFNKINSAAVTIDYRGLTV
                     LNGSIACDCLTTPAGHEPIIRLFEDSSASITLDARESNGAVKGSAIRLKYNENYLFIN
                     RLGANIFVDGEVRLQVKEDDAFIKCGSARFCFTNDPFSFFPDQSRTDLGQSYNTWRNV
                     YCDTLRCDDVRSTSDSKFKENINYISITKGKIFRRSFLMDTETPFSDFLKNELKVATF
                     NYKNFSEEDGNNQQIGFIANDIKDSKIGSMFIYNYGEEIGLKFSMAGYITVIAAALQE
                     EIIKREELEVKINQIESVLCEGV"
     gene            38260..38442
                     /locus_tag="KRH23_002363"
     CDS             38260..38442
                     /locus_tag="KRH23_002363"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5225641.1"
                     /translation="MEVDLKIMFENALDEIKKLTTDVLLYKTLLIQKEKDIEDNEKNI
                     EILGKKIEELEESKSK"
     gene            38456..>39127
                     /locus_tag="KRH23_002364"
     CDS             38456..>39127
                     /locus_tag="KRH23_002364"
                     /inference="COORDINATES: protein motif:HMM:NF022117.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BppU family phage baseplate upper protein"
                     /protein_id="HHS5225642.1"
                     /translation="MREYEVKEYFLEIDFSCYETKNVVKKLIYNENDINTAFINIQLK
                     NDGKIINLTDYEVIANIWKNIGNKVQNPCKILNGELGEIEVPLTRQSLKGAGVNPFTI
                     SIVNGERSLESPRFYYRVEEAIVSDDDIENADEFGVLVLLISQVKEVLKDNDILVTRV
                     ENLENLIEEQEEIRSTQETTRETNELTRETNEKERKINELTRQTNETTRESNEEERKT
                     SETSRK"
BASE COUNT        16631 a         3960 c         6581 g        11955 t
ORIGIN      
        1 ttgtaaaaag cataaaaata atataattaa ttaatgagat aaaagtggat aaaaatattg
       61 ggagtttaat ttttgtgaaa ttaaaaatat taaagctaat ctacaaatat agaatatatt
      121 ctaagacgaa tttttataat tactaaataa aataaattaa tcaatatagt tttttaatat
      181 aaacaaaaaa taaaaaactt atataaataa aatgcttgtt tttcttgtat tatttatata
      241 aatattgaaa tttgtctagt tatacgtttt tattgaccag ttatgcagtt gatattgaat
      301 attctaaata ttggtgttat tttataggtg gtttaaacat attaggggga ttttatatat
      361 gatttgtatg atttatagag aatgtataaa atagtaaagg tttagagcca tgtttagtgg
      421 attgcagaat atgcatatag aatgattctt gtaaattaag ttagacatag gaaatatata
      481 atttgtattg gatgattgat tttatggtgt atgcttttaa cttctataat gggaaagtaa
      541 agatgtactc ccaatacatc tttactttag cagaagttat agttatttat aaagtacaaa
      601 aaattatata tttattagag tagataaatc taaaaaggtt tttctagaaa aatttagttt
      661 taattgtatc tacttactaa taataagact tgatgtaagc aggtttcaac taccgtttct
      721 ccatattctg atataaaatc atctaactgt gtatctaaaa aattacaata atcatatgaa
      781 ctactgatgt aagcagttag tatatgtgta catttgtcta tttctccaat aaacatatta
      841 tccatccccc taaaaaattt agtaaaaata aaaagtcgca ttctattagt caattaacat
      901 aatttataaa attttttagt actagtttct ataacttaac tccttaaggt taaatattcc
      961 cagttttacc aatttagttt tattctacaa gtatataata ctagaagatg cttcattatt
     1021 caacatgctt gtttgagaat agaaaatatt ctaaaattat aattgttttt aaaaataaga
     1081 ttcaagataa ataaagttat atgcaactat ttaataatct ttccataata aggacagtag
     1141 gttctattct taaaaaactc catctttaaa tttaaagaat aactacaatt tgaacaacaa
     1201 taaaatttcc aatcaataaa aatatcaaaa ataataaaaa taattgaaaa tgtataattt
     1261 cccagaaaaa taataaatgt aactccaata ataaacacac ctataaatta taaaataatt
     1321 taagctttat ttaaggttag tattatattt atataagatt taagttttaa tatatatgtg
     1381 taattaaaat gatttaggag gagaaatata ttggtaaatt gggaaataaa aaaattggct
     1441 aaatctaaga gtatgtttat atctctaggg atattagtgt taatactaat gattagtatc
     1501 tttattacgc ctgttttaga aacagaaagt tattatatag ataaagaaaa aggacgtata
     1561 gaagatacaa gaagtggtat cgacgtaggt aatgagaaat ttcaaaataa gattaatgtt
     1621 ttaaagcagt tttcaaatca aacagataca ggtgaatttt ctaaaaaaat tgaattaatg
     1681 tcaaagaaaa aacttgataa tctaagtgtg aatgaatata aggatattag tttttggaaa
     1741 gtatttaact atagagttac aaattcactt ataaatgtag gaatgttaat cattatatct
     1801 ataattatat ccaatattta cgtagatgaa gtcgttactt cggtaaaaga tatcatacta
     1861 tcatcaaaag agaagaaaaa agcattaaag tctaaaatat ttgttgcttt attagttcca
     1921 ttagtaattt attctgttta tttaatggga atatttatta taacttgtat gcaacaagga
     1981 gtacctgtta atggagactt agaatctttt agaatagtag acaatgtagt tgcattgaaa
     2041 actaatttaa gtataacaaa gtatgtaata ttaaatatag gcatagagct tttgatgttt
     2101 gaaggatggg ccatgatagc catatttggg tcttttataa gtaagtcttc aatatcttca
     2161 ataagttttt ttatatttat tatatctata actaagataa tgtcggtaat ccatatatta
     2221 cctaaaaaat tactttcagt tgtatcaaat gtaaattatt atgatttgat atttggtttt
     2281 aataaaataa taggaaatta tctaggtgat attatgatat ttaaagtgaa tatagacatt
     2341 gtcaatatag caataggact tttgatggca atattgatag gtgctatgtc attatgtttt
     2401 ttagtaataa aatcagatta tataagtaga taaaagggga gttaagatga ataaattaga
     2461 aatagaaaat ctttcaaaga tatatggtaa aaaagtagca aacgacaaga ttacagtaac
     2521 tctggaaaat ggagtttatg gtcttctagg accaaatgga gcaggaaaat ctacattaat
     2581 gaaacaaata acaacgttga taaaacctga tgaaggtcag atactttata atggtgagga
     2641 tatatttaaa atggatgctg attatagaaa tattttagga tatttgccac aagaatttgg
     2701 agtttataaa aattttacag caaaagaatt tttacagtat attggagctt taaaaggttt
     2761 aaggggaaaa tatttaaata gtaagatagg agaattatta gatttagtag gtctttatga
     2821 tgtgagaaat aagtctatag gaaaattttc aggaggtatg aagaggagag ttgggatagc
     2881 acaagtttta ctaaacgacc ctaagataat agtccttgat gagccaacag caggtcttga
     2941 cccacaagaa agagctagat ttaggaattt aatagcaaaa atgtctagag ataagataat
     3001 aatactttct actcatataa tttccgatat agaatcagtt gcaaaggaaa caataatgat
     3061 taaagatggc aaactcctaa tgaaaggaac acacaaagac atattaagtc acatggaaaa
     3121 taaagtatat aatgttcaag ttaaaaatga atgtgaagtt gatgatatac aatctaaata
     3181 taaggttgta agtattcaaa gtgatattaa ttcaatagta cttagaattg tttcagagga
     3241 tattccaagc gaggataata tacaaccagt tcaagcaaaa ttcgaagatg tatacatgtt
     3301 ttattttgat ttagaagatg caagggaggt gtagtagaaa tgatgtattt agttaaagct
     3361 gaaatgataa aaatattaaa atcaaagagt gtttggataa tttggctgtt tttaatattt
     3421 tttggatttt ttctgattag aaagtttgat gttttagata cttatgcaga tatattttac
     3481 aagatagaag gctcaatacc tctaataggt tttataatgt ttataataac ttctggaaat
     3541 tacattaaag aatatgattc taatatgaca ggtttaataa atacaactaa aaagggaaaa
     3601 aaatcagtag tattatcaaa actagtagct aatggattaa ttttatctat tattaatatt
     3661 tcttttatat tgttagtagg aattagaggt tttagttttt ttgattttaa aaatttaaat
     3721 gaatcgattc ataacttatg gtactttgga aatagtaatt taaatcttac agtaatacaa
     3781 atgtatataa ttgttatatt gactactatt tttgcttctt ttatatttgc acaaataggc
     3841 ttaacacttt catctatatt taaatcggct gtaattccat ttatactagg tggattgata
     3901 atggcaattc catactttag tgtaggtttt ataccagata aagctataaa atttatgtca
     3961 gtgactccaa attggattat gatgagccaa caaatggtta agtataatgt accaattatt
     4021 ttgatagttt tttctatagt aatctcaatt atattaatga tagtgttaac taaaataaca
     4081 tatgaaaatt ttacatcaag caaaaggttt taactaaaaa taatagtaat tttatttata
     4141 ttttagttta attaaagata agataaatga attttagata aaatatatgc taatatatat
     4201 gtaaattatt acaggaggtt gtttatggaa aatcgtgttt taataataga tgatgaagta
     4261 gaaatattga agcttttaga aactgtccta aaaaaagagg gccttaataa tatatatact
     4321 gcaaaaacta aaaaagaagg attagaatta tttaaaagta ttaatcctga tttgattgta
     4381 ttggatatta tgttaccaga tggcgaagga ctttttgtac aacaaaaagt cacaaaaatt
     4441 taattactaa ttcaccattt ttttgaacct ctattctatc aattgcagat gtccaaagcg
     4501 ttcttttttc tgagtaattc atatcataat aattatcttc aaagtttgta tctaaaaaaa
     4561 ttttcattga ttttaaatct ttttcaacag attctgcttc attttctgct ttattgagtt
     4621 ctgataaatc atcatttaac tttttatatt taaatttata agtatcttta tttattaaat
     4681 catcgaaata taaatcttgc aatttttcta tttgtttttc taacttattt cttaagtttt
     4741 tattattatt ttttttctgt ctttttttat tgtttgattc atgttctaat attgtctttt
     4801 gtaattcttt tttcacattt tccaataaaa aagcttcaac ttttttctcg tttagataag
     4861 gcttattatc acaaagtttt gtagcgaaag agagtggaca tctataataa agataatgtc
     4921 tattggcacc acctctagaa tgtacacctc ccatttttct gccacaacta ccacaaacta
     4981 tcattccgct aaaaagataa ttcatcttaa atttattctc tgaaaatcgt atattctttt
     5041 ttagaagagt ttggacgaaa ttaaactgct ctctgcttat aattggctca caatagtttt
     5101 ctacaactaa atctcctttt tcatatatac ctatgtatat tttatttttt agcattttag
     5161 gcatccattt aaacatgtat ttagtgctga acttggtgtt tatatgttga attgtttttg
     5221 caagagatga aaaatcttgg taagcgtcga aagcttctct tacaatagat gcttcatctt
     5281 ctttaatcac taaatgtttg tcttttattt tgtatccaaa tggaacgcta ccagtaataa
     5341 cttcaccacg ttttaattta tcttgaaaaa caaatttaat tctttcagaa gtctgtgctg
     5401 cttcattttc tgcaacagaa agcataatat ttatatgtaa tctaccagca gcagtcgaag
     5461 aatcataatc ttcaagtatt gttttccaat cacatttatg tttttctaat gtttccatta
     5521 ttttataata gtttttgaca ccacgactta atctgtcaat tttagttatc ataactaaat
     5581 ctattttatt atttttaaca tcttcaatca tgcgttttaa attaggtctt tttaagtttg
     5641 ttgcagaata accttcatct atgtatttat ctactataat aaaattatta tcttttgagt
     5701 attgttctaa agcttctgtt tgtgttctaa tactatctcc atgcaatact tgttcttctg
     5761 tactaacacg tatataaaga gcaacacgtt ttattttatc cattataaaa ccctcccaac
     5821 ttatgtatag tgcctagtat aaattcacta ggcacaatta aatagaatta attaatatta
     5881 agtttatttt tcaaagcttc ttgcaataac tgagaaaaat ttatattatt tttttcagct
     5941 tctttattta gccacgaagg tatagataaa gtttttttaa ttgacttact atcatattct
     6001 tttattgttt cttttaaatt aacttttacc aatatagcag tttgattttc tttagtacta
     6061 atattattta gttgggtagg ttttggaatt tctaaaccat ctgaatataa atcaaataat
     6121 tccagtttta aagcatcctc tgccataagg aaagcttttt ctaagttctc accacaagtt
     6181 attatatttg aaaaatcata aaaattaact tcatagtcac ctttatcatg ttttgctata
     6241 actgctggaa atatatattc atttttgtac atattttcac cgcctttata aaattagtta
     6301 caaatattaa ttttcttcat aataatcatg agattttgca aaacttatag catccaatac
     6361 tttttgttct atattgtaat atctagctac attaagtacc tcattataat gttctttttc
     6421 attctcatta tagaaaatgt aatagtctaa agcttcttga ataaaactat actcactatc
     6481 ataccttatc atatcacaaa ttgttcttgc aggatttgtt atccaaacac cttttctaac
     6541 ttcttctaca taagataagt ctaaattttt aacagggtat actgtaaaat aatctgtatc
     6601 aatctcttta tctataaaag cagattgagc tattatatga ttgtctggaa aattagttat
     6661 tcctaataag cttcctgcat attctccaca tagcacaaca ttattgaaag agtttcttat
     6721 tactcctgta aagtccacct atcattcctc caaacataat ttttatttga ttttgatgct
     6781 ataaaagtgt gtattggaac tataaaattg cttactcttt tataaacagt tgcaaactca
     6841 ggcttagatt caatacctct taatctatta tatccatgct ctaaagtatt aaaattctct
     6901 aattggaaca tgtacatttt ttctggtata tttttatatt tgtctatata caatcttact
     6961 aaatcattgc tattatatcc ttttaagtaa ctcaatgaat atatatcaaa taaatctttt
     7021 aaccttctat taatctgttt actttcacaa gcatgtatct tatcaactaa tattaattct
     7081 ggtgtatatc cattaattgt aactaaccca cccaatgaat atttctctga gtctaaagta
     7141 gaccacttaa agtttacatc tatactaaat ctagtaatta attcagcagc tctataaaca
     7201 cctatagtta cactttcatt tttagtagct tcacttgttg ctatttcttt tataacttta
     7261 tatatgactt taaatctact atactgagaa caagctatta tatctttttt gaaattaagc
     7321 catttattgt aatcagttcc atgtatatct atatcttttg ttaatcttct gttaccataa
     7381 ttatattttt taaaggcaca taataatgtt attccacctt taaaaatcat atcattaaaa
     7441 ctattgctat gactcataca atagataaag tcctctatat aatctagtgt gctattatta
     7501 tcatgaaaat tgttactatt actccactta ttattaatca acagtatcat ttcctccttt
     7561 ctctaactat atttatatta taacaaaaat attgatacgt atcaatacgt attagatttt
     7621 cttatactat aattttgtgt ttttatttag aaataagtat ctttttttct atgttttaaa
     7681 tagtttttta taaatttata aaattgtttt ttaatcaagt tttctaggtt agttatacaa
     7741 tttgaaagct ttattttttt tatataatga ctttgaatta aagctgtttt tttatcaact
     7801 ccacatatat acataatttc ataaatattt gtaatattac aatataacaa aattatatct
     7861 ggacatagaa gatattgtgt aaaaatttct gcttctaatt caagtaattt atttctagaa
     7921 tttaatttta caatacttgt ctttttagtg tgccccaata ctatgtgagc tatttcatga
     7981 gtaagcgtcc aatgtacaga ataaaaagaa taatcactat tataacaaat tatatgttta
     8041 ctatcttttt cactccaaaa agcgaagcct tggcaatcat atttttctat tataaaatca
     8101 atgtcttttt ttattactct tgaaaattct atatatgtat aaaccttgaa atcatcagaa
     8161 ttactgataa tttcaagggg acaaactggg taaagtcatt atctttttat ctaaaataaa
     8221 tttgtaagct gattgcctta aataagtttg cactaatcct cattaattgt tttatcagaa
     8281 aaagaaaaga aatatttttt tattactttt ctttcttctt tggatagttt taagtaattt
     8341 ctaaatatct ctatgtccga ttcttctagg ttatattcta ttgcaacttt ttgaaggatg
     8401 tcatcctgtt ttgtaaacat gtttcctatt ccagttcgta accattcctc attaatatta
     8461 aattcaaaac aagtaatttt aataatttta tctgttacat ttctataacc tttttcaata
     8521 tttgatagat aattttgtgc tattgtaagt cttgacccaa aattcttttg tgaaagatta
     8581 aaatataatc gaataagctt aagtctttca tttatatctg tttttataaa catatcacca
     8641 gagccaaacc taatccaatc ttcatttaca ttaaattcag aacaaatttg tgatatatga
     8701 atatttttgg ggattctttg tccagtttca aacattgcta aagtagattg agagactttg
     8761 attttgttac taaagtctct ttgattcatg tttaaataac ttctaagtat tgctatcctt
     8821 tcattcattt aaaatttatt cctttcaaat aggagttatt ttttaagaga attatcagca
     8881 ttatcatata tttttattaa atcctcttca ttttgtggat tgccatttct tgcaaccata
     8941 tgactattgt tttcatttat atatttactt ctgtaatctt gatacaattc gtcatcttct
     9001 aagattgtgt caaccaatga gtatacatat ttttttattg cttttctttg ttctccagaa
     9061 agtttcagat aactttcaag tatttttaca tctaaattat caagattata tttattagaa
     9121 agctcaaata ttattgtatt atcattttct ataaacattt ccccaattcc gttacgaaac
     9181 cattcttcac ttataccaaa ttcagaacaa attttggata tatgaatatc ttttggcgtt
     9241 cttgtaccaa tttcccacat agccaatgtt gaagaaccaa caagtatatg tttgctaaat
     9301 tcggcttgac tcataccgaa gtgacttcta atttgcttta gtctttcatt cataaaatcg
     9361 cctcctatta aggatattaa cataatgata ctcacaaagc aagtgaaaag gctaataaag
     9421 tgttgactta ttacttgcct agtggtaata tgtacttaca aagcgagtga aggaggttgg
     9481 aaatatgaat aaagttattg ataataaaac aaaaaaaatg attgaagcag aggaaagagt
     9541 aaaaaatgaa tttcttagta agaaaattga tagtgatgat ttaatgaaag aaattgtaaa
     9601 aatgccatac gagcaaaaag ttaagatgtt ttacataatg aaaggtgcaa atattacaaa
     9661 tgattcagat gtatcagtta tttaagctag ataattaagt gaggtgagaa agttgtctat
     9721 atttgaactc ataattttcc cctttctaat aaaatttagc tatgtagcta gtaagaaaat
     9781 tatagcatat atgggagaat atggggttaa ctaataatat tatcttaata agtaattaaa
     9841 ctaaaaaatg gggggaacgc atatgtcaaa accatacgaa aaaattgaaa ctgagaataa
     9901 aatgaacatg gatttatttt gcaaaggata tgcaagagca aaagaaatga tggcaaaaag
     9961 actttttgat gtagatttag aaataaagta cacatataga aagaaaacag aggaagaaat
    10021 gaaagctgaa aaagaaaaaa agttagaaaa ggaagtaatt taattggaac ttaaaaatta
    10081 cataaataaa aagtgtctta taattcgcag ttataagaca cttcacaaaa taactttgtt
    10141 gtcaaagcta taaaatcata tctactcttt attatagcag ataagacaac agagttcaat
    10201 aaacacgcta aaatggagcg attaacgagc ttgtaatagg tattaacatt gtaacgatat
    10261 aaagtatcta tacaaatata taacactaga tactaataga tagatgctaa taaaagacta
    10321 aagaggtact gctatgaaga gttttataag agagaaaaag atatattgta atgattattt
    10381 agagatagat ataataccaa gagcagatgt acaaacaaaa ggtaagagag gtaaaagaga
    10441 atacatatct aaaccaaaac aaaagaattt aaatgataag aacgctaaaa ggtattttac
    10501 acaatcagtt aatacaaact ttactaaaaa tgatttagtt gtacattcca catatgcacc
    10561 agaattttta ccagaaacat tagaagaagc tgaaaaagaa gttagaaact atataagaag
    10621 gattgattat aaaagaaaga aagaagggct tgaaccagta aaatatatgc ttataacaga
    10681 atttggagaa aagaaagatg gaactaaaag agttcaccac cacattatta taaatggtgg
    10741 attagatagg gatataatag aaaaactttg gtctaaaaag caaaaaggta gaaaagaagg
    10801 cgaaaagctt ggatggataa atacacacag gcttcaacct aatgaatatg gattgcagaa
    10861 tctatgcaat tatttgatga aagacccaaa aggtaaaaaa cgatggagtt cttctcgaaa
    10921 tttaaagaaa ccttttcaag tttgtaatga tagtcgatac agtaaaagaa aagtaatgga
    10981 tatagtaaga aatgatttag ataatagaat gttttgggaa aaacaataca agggctatat
    11041 atttacagaa tgcaaggcta catataacga tataacagga gttagtttat acataaagat
    11101 gcgaagatta aaatgaggtg attatatgta tttaagagta tgtaagtgtt gtaagaaaga
    11161 atttgaaaca aatttatatt caaaaacata ttgttcttat gtttgtaaaa acaagtttaa
    11221 gaatgagaaa agaaaaaaag aaaagaaaga aggtaatgaa aatgaataaa gaaatagaag
    11281 caatatgtat tgaagttgag aaacgtattt gtaaaatctg taaatataat aatacttgta
    11341 atgttgaaaa gaaaaatggt cgtatatgta gtttttttga agaaaaaagt aagatagaaa
    11401 aattactaga aaagagtaat ttcataagtg ctatggattt tagattaaaa aatataagta
    11461 tgaaagaagt tgaatcttat tgtaaagaga ataataaaaa aatagaaatt tgcggatggg
    11521 gaagtgggca agtaatgata tttacagata aaaggaaggc aaaaactaat gactaataaa
    11581 gagaaaataa aaggctttat gctagctgat ttatgccaag atgaatctaa taaaagaaga
    11641 gaaaaagaca cttactatgc agggaaaaat catactttta actacgactt ataccctgtc
    11701 ataacaaagg atataaatag agcaaaggta tatagaacta aaaaagaagc taagagagag
    11761 cttgaaacat taaataaaaa gtgtattcat aattattttg aaattgttag cttcaaaaaa
    11821 tatattaaaa atatgagtaa taaagaaatg ctagaattta tatctatgaa agaaaataaa
    11881 gcatataaaa agtattctaa agagatttgt aatatatgca aaagtataaa atttaattgt
    11941 gaaagtcttt attgtgaaga agcctatagt gattggttaa aagaaaatgc atggggcaaa
    12001 aaaaggggtg ataaaaatga ctaatgaaga atttgaaaaa atagaagaaa tatattgtag
    12061 atacaaagag ttaattagta caaaagaaga agcgaaagaa ataaaagaaa ttatataaaa
    12121 aaagaagtta taaatatgct agaaaaagta attcaagatt gcagtgaaaa aatagaagct
    12181 attaagatgc caagaaatta aaaaagataa agtaatctag tttaattaat aattaagcga
    12241 taaattataa tataaaattc cttataggaa aaaggagcat aaaatatgga tgataaaaaa
    12301 ctacaacaaa gatataaaaa taaagttgct aatgcacaag gtcaacactt tgagaattac
    12361 ataaattcag cttgtataat ttatagaaat gataataggg ctgaaataga taaaacacca
    12421 gaaccattta gagtattaag caaggataag acagggaaat ttacaggtag atttatagct
    12481 aatgcacaac cagatttcaa aggtgcttta aagactggta tgtgtatatg ctttgaagct
    12541 aaatacacgc ttaaagataa tataaaaaga agtgttttaa ctaattcgca actagaaact
    12601 ttagataggt attaccacat aggagcaata acaggggttt gtataggtat acaagataag
    12661 ttttacttca taccattttt agtatggaga aatatgaaaa attgttttgg tagacaatat
    12721 gtaaaacaag aagatataaa aagatttgaa ataaaatttt ttaatggagc tgtattattt
    12781 ttagactata taactaaaga cgagaaaata ttaaatgaga attatagctt attaagaaaa
    12841 aaatttgaaa atgaaataga tgatagcatt aaaaaagtga ggggataaaa tgtttttaaa
    12901 cttatatact aaaaaagatt ttaatgaaat aaaagcagaa tatgaaatag ctattagtag
    12961 aatagaagaa ttaaaagata aatgttcaag gaaagaaaaa ataatttcag atttagaaaa
    13021 taaaaatgct gcactgcata cagaaaaaat gtctttaaaa attagatatg aaaatgaaca
    13081 aaatataaaa aagggtatgg aagcaggagc tgaaatttta agagaagaaa tagaaaaatt
    13141 aaaagaagaa aatgaaattt tgaaaaaaac aatagaaact tttaataata aaattaaaga
    13201 aatagaatta aaatttaaaa agacactaaa tgataaaata actagacttg aagctataaa
    13261 agcgagaacg aaaaggttta gaaaaaagaa aaaaatagaa aaaattatcg aggaactaga
    13321 attaaaaagt ttcttagaat aaaaggttga ttattatgtt attagctaat agagacaaaa
    13381 taatacagct tgcaagtaaa atagtagaac tatacaatgt tgaagattta gaagcgacaa
    13441 taaaagctat acagtactta gaaaaagtag aaataaatgg agttatacaa gaagaagaat
    13501 ataataagct tctaaaaata attgtaggga gctgagtaaa tgcaaaagaa agttataaat
    13561 cattttatag actgtattaa gaaaagtaga caaagaatgt taattgaaaa aggggataaa
    13621 tattatttaa gtgatggtat ttgtatattc ataattgata aaaaagaaat ggtattaaat
    13681 cctaaaatgt tcttatttaa tagtgaaaaa gctaaaaaaa tagttggaga tataaaagaa
    13741 actggatacc aagaagttgt tttaaaatat tatataccag ttcatggtat tgtatatcat
    13801 aaatatatat gtgaagattt tgaaatttat ttagatgaag tctttgtaaa agtatttgat
    13861 aaatttgata aagttgaagc aatagactca aagtctccag taagaatttc tatgaagggt
    13921 catatcttag gttatttgat gccagtgaca ataaaagaaa attaaaaata aaaaaatgga
    13981 ggtaaagcta tgaaaatcat atctattcta agcttcaaag gtggtacagg taaaacaata
    14041 acaagtgcaa acatggcaga tattttatct gtagtacata agaaaagagt gctgttaata
    14101 gatgcagata aacaaggtaa tttatcacaa tacttctcaa aatttgagga aaaaaaagga
    14161 aaaggtacag cagaaatgtt gcttgaagat aatgcaaata tacatgaata catatgtaag
    14221 actgaaaata aaaatataga tattataact agcaatatgt atttatatca agctgataga
    14281 atgttatttg atagtgatag agataaattt agtatattaa aaagattact agaaaaagtt
    14341 aaaaatgaat atgatttttg cataattgac aatgcaccaa gtgtagatat agtaacaatc
    14401 aattctctag tagcgtcaga tgaagtaatt ataacagtaa gagcagataa tttttctctt
    14461 aaaggaataa aggaattgct ggaacaaata gaaaatgcta aacatgtaaa taaaaaaata
    14521 aaatttaaag ggtgcataat aacgcattat caaaacaatg atgtaaataa tcaatttata
    14581 actttactac agaatatctg caaagtattt gaaactgtaa taagattaaa taaaaatgta
    14641 gctgaaagta cattttatca aaaaacaata atgaaatata acaaaagatg tggtgcgaca
    14701 atagactata aaaagttagt taatgagtat ctaaatatag aataaaaaat gtgtccgaat
    14761 tggacacata gaaaggaaaa agtaaaatgg cttttaatat gtttgaagca attagtaata
    14821 gtaataatag aaaactagaa aataacaata aaaatattaa aaataaaaaa acagaaataa
    14881 aaaatataag tgtttatgat ttagtaccat cagaagataa tttttattca gttgaagata
    14941 tagaagattt aaaatcgtct atagaaatgt ttggaataaa acaaaatcta ttagtaagag
    15001 aaaacgaaga taataaatat acaataatag caggtcatag aagaagatta gcagtattga
    15061 agttattaga agaaaacaaa gaaaatgaaa aatttgaaat gatgccttgt atggtagaaa
    15121 aaataactgg aataagagcg aaaatattat taataacaac taattcaact gcaagagaat
    15181 tgacagattt tgaaaaaatg aaacaggcag tagaaatgag gaagttatta gaagagttaa
    15241 gagcagaaga agatataaaa ggtaaaacta gggatttagt tgctaaaatg ttaaatacat
    15301 cagctggtca aatagcaagg ctagagaaca tatctaagaa gttaatgcca aattttaaaa
    15361 atgagtttga gaaagaaaat ataaatgtat ctacagcata cgaattatca agattggaag
    15421 aagctgaaca acgaagttta tttgaagaat atcaaggcaa aggaagctta agcatcaagg
    15481 atgttacaga gaagtcaaaa gagaaaaaaa gtgaaataag tgtatcaaca acttataaaa
    15541 ttgaagaaga tgaaaatgag gttgaagaaa cagaagaaat tgaaaatgta attgattttc
    15601 catctacaac aatagaagat gaaatagagg aaagaaaagt ttctaaaaca atttttgaaa
    15661 tattaaaaga tatgaaaatc agaaagtttg cagagtttgt ttgttctcaa tgtaatgtaa
    15721 ctggtacatt ttgcgactat gcaatggaat gtaatgataa aaacggaaaa gggagtgttg
    15781 atatatgcat aaaatggcta aagatggaag cacaagaaat ggagtagata taagacataa
    15841 taaaagtgga tacttagata atacagcata tgaagctata agaaaaattg acaaagagaa
    15901 acaagaagct aatatattaa ttgaattaat taaaaaaatg gctaaggtag caggttttga
    15961 gataatagga agaatagagc ttagaaataa aaaaagtaga gttatatata agtaataaat
    16021 ttaaggaggt tggtttaaat gaatcttaat tttaaatcta caaaaatacc tatatatgat
    16081 atagaaaatt cagcaggtat aagttatcca agaagaacag gaacaagaga tagcaacact
    16141 cattacaaag ctactaaaaa taaagttatt tttagagtaa aaaaagaaga tatatttatt
    16201 aggtttttag aaactgggga aaaagaactt aatgaaaaat attatttata tattgagtat
    16261 ttaaaagaga ttattttaaa agaagaagtt gaatctttta aaaaaggatt tgaaaaagct
    16321 gatatttggg ctggtaaata cttgaacaac tttgaatatt taaataaatt aatttgggat
    16381 attaaagaaa agagacaatt caaaatgtta gaagaagaaa aagttgatac actagagaaa
    16441 gctaaaaata ttaaatttcc ttgtttttca aaatattcgg gtgagtatat atataatgta
    16501 atgcaaactg atttagaaca ttgcattgct tattatgtag gaaatttaag caatagagaa
    16561 tttgattttt caaatattgg tgttagtcaa ttaaaataca atcagtcacc agaaagaact
    16621 agaagttata actgcataaa atatttacta aatgaatttt atcctcatat atcacgaaat
    16681 ttattagctt attttaaata tataaatata gatgatgcaa aaagaattac ttttaaaaac
    16741 ggaaaatata aagataaaac agtatattat gttttcaaag aaaatcgaag ttatatagag
    16801 tggtttttac aaaacacaaa gaaaactata tataatatta gattgataac agctattaca
    16861 ttaattagag aacaagagta gaaaggaagt tattgcatgc taaaaggaat aggagaaggg
    16921 actgaaaata taaatattga tatgttaatt gaaaaggtaa caaatatagc agcagagaag
    16981 gctatatcta catatgaaaa tagaagaaaa gaagagctta agtattcgta tgatagaaaa
    17041 cttagaaata caaagttatt actaaaacat tataaagatt ttaaaagaca tgttaataat
    17101 tctattttta aagtatcaaa tgtaagtgaa aatgctattg agatattaga agaattaata
    17161 aacactaaaa taacagaaaa cttatttgta gaaagtataa gtaatagtgt atcacgtaca
    17221 aatataataa tatctcatat aaatacgatg ataaatattt atgaagctta tagtaaacag
    17281 catggagaac tagaagaaag aaagtataga ataatatata aaagattcat agatgaaaag
    17341 caatggagta taaaagaaat agctacatct gaaaatatag acaatagaac tgtatataga
    17401 gatataaacc tagcttgtgg gaaaatatct gtatttctat ttggtataga tggagtaaat
    17461 aaattctaat ataatagttg aatgtcatgt ttttatagaa taataaaata acatgttaat
    17521 tagttaaata aatgcaagat agttatttca atgtatacag taatataatt caatcaatac
    17581 agaaagttat atgataagaa tgatatgtca ataagtgttc atatacaaaa caatttcaaa
    17641 atgctaatat ataaagtgta agattagatt tattgtgaac cagaaatata tactgtaaaa
    17701 aataaaaaag gattatctct ttaaatatat tgagatagtc ctttttgttt ttgtgatagg
    17761 agtgattaaa tgagtaaagt tatatgtgat aagtgtaatc atagttttaa agttaattta
    17821 aaagatataa aaacatactt cattgatgat atagaaataa aatactttaa atgcagaaaa
    17881 tgtaaagaaa gatatattat atcttttgaa gatgataaat taaaagaaat gaaaaagaat
    17941 tataatgaaa tgttaaatga ggaaaaagag tatagagcaa atggattaga ctataaagaa
    18001 acaccactat ggttaatgat agatagtttt aataatttag ttgaatatca aaataaattg
    18061 aaagtgaaag tttatggtga aactatatgc caatgaaacg aatctgtaaa tgtggtaaaa
    18121 agattgatta tgataagaaa atgtgtgaag aatgttataa aagatacaat aagacaaata
    18181 aaaagatata tgattataaa aaatataata aaaaatataa ttcagagaaa agaaataatc
    18241 aagagtttta tggttctaag aattggagaa tagcaaaaga taaagctaga gttagagaca
    18301 agaacttatg taggttatgt tatgataata aaactatcaa gaaggctgat ttggtgcatc
    18361 atattgaaga ggtaaagaaa tgtaaagata aaatatatga tactaataat cttatatgtt
    18421 tgtgtgaaag atgccataga gaggtgcatt tattatataa aagtaaagca agtataataa
    18481 aagaaaaatt gaaagactta gtagaagaag gattttaaga atatagaaaa cttatgcata
    18541 atcttacatt aagcagaaaa acaaagccct ttagaatcga agctagaggt agtagggggg
    18601 cataaaaaag tttttggagg ggtagacgag cgatagggtg gagtcaactg tgcaaccaaa
    18661 cataattttt caaagggggt ggtttattgg aaaatagtag gggggagggg gcaagtctaa
    18721 aaacatatga aataataccg aaaccaccag caattttatc taaattagga aaagaaaagt
    18781 atactgaaat tgcaaaaagt ttggtagatg aagaaaaatg gaaagtcgga gatgaaatag
    18841 cattaactgc attatgtgta aattatcagc gttggatgca agccgaaaaa gcaattaaaa
    18901 ctaataaaga tttatgtttt gaaacagaaa caggatatag gcaacaaata ccagagattt
    18961 caattgcgaa taactgtatg aaaatgatgt taacctttat aaaagaattt gctttaactc
    19021 caagagaaag agtaaagtta aaagaacttg ttttaaatcc tacagaggta gaaaatatag
    19081 acaaagaact agatgacatg attcagaaat aaggtaatta tatgaatgaa aaattaaaag
    19141 aaataataga taaacaattg acttggaatt tggatgatgc cattggagaa ctaaaaaata
    19201 agtgggataa tgaaaaatat tactatgatg tagaagaagc taagaaattt cttacctttg
    19261 caagcaagtt ggagcttgat aaaggcaaaa aaggtaaaaa aataaagtta ataaaatttc
    19321 aatttgaaat atgcaccagt attatttgtg ttaaaagaag aagtgataat ttaagaagat
    19381 ttagagaagc acatataaat atacctcgta aaaattctaa gtcattcttg atagccctta
    19441 tagctagtta cttatatttc tgtaaaaatg agtttggaag cgaaacaata ataactgcaa
    19501 acagtagaga ccaagcatca ttacttttta atacaataca tcacatggtt aagactaata
    19561 aaactttaaa aaaatatgta aatatacttg aaagtagaaa gtatatgttt aaaaagaata
    19621 tgaacgcata tttgagagtt ttatcatcag atgcaggaac agcagacagt tatgcaggct
    19681 atgtttgtat aattgatgaa atccatgaag ctaaaaatag acaattatat gataagttaa
    19741 aaactggagc tggaatttgg gaagaaccct taatgttaac aataacaact gcaagttctg
    19801 gcgataatcc agaaaatcta gagtttgaat tatattcgta ttcaaaagag ttaatgaaag
    19861 gcgaatttga ggatgattct tttttttatg caatttatga agcagaggaa aagtgtgaat
    19921 tattggatga agaacaatgg tttaaagcta atccagcact tggaacattt agaagttatg
    19981 aagaactgaa aaaccttgca ataagagcca caagattaaa gacacaagaa gcagcattta
    20041 gaaggttata tttaaatcaa catgttgcac ttgatggtga aggtgcaata aatatggaat
    20101 tgtgggaaaa agcagaaaga gaaataaatt tagaagaatt gagaaatatg aaaacttggg
    20161 atggaatgga catgggttca acacaagaca taacagccta tgtgatggtt ttttatgatg
    20221 aagatactaa taagtatata atttacccat ttttatttac cccaaaagat acaattgaag
    20281 aaagaagtga aagggatgat attcgatatg atattttagt acaagaaaaa gaattaattg
    20341 cattagaagg tcgttctatt aactatcaat atatgcatga ttatttagaa gaaactaaaa
    20401 taaaatatga attagaaact caagaaatag gcttcgatag atggggttct ataggaataa
    20461 gaaataagct agaagaagat tatgacgttt tgccatttgg gcaaggatat agttctatgt
    20521 caccagcagt tcgagatttt gaaaatatct tgttagatga aagaataata atagctaaaa
    20581 atagtctttt tagacgaatg gcaaagaatg ttgttgcagt tatggatgat gctggaaata
    20641 taaaatattc aaagaaaaga agtaaatata aaatagatgg tatcatagca atgctaatgg
    20701 gaatatcaag agcaattttt aataatgagg gtgaacaatt ttcaacacaa aataatgtag
    20761 ataaattttt aaataaagta atgggaggtg aagaagatta atgctgttaa taaaataaga
    20821 aaatatatag ctaataaaat agaccctaca cccaaaagtg taggtgatag tgatatttta
    20881 acatggttag gaattgatga aacaagtaaa aatataagaa gtgaaataac atattttaca
    20941 tgtttgaaga ttttatcaga aggcatcgga aaactttctt tgaaaacata taaaagaaca
    21001 gaaaaaggaa gagaagcaat tgaattatca gatataagta gagttttaaa agtaagacct
    21061 aatgagtata caacaccagc tattttttgg tcaactatag agcagaacag aaatcatttt
    21121 ggaaatgcat atgtgtggtg tagatggagt ggagctaaat taattgattt atggataatg
    21181 caaagtgatt gtgttgaaat atatgtagat aatcatggtt tctttggtaa aaaaaataaa
    21241 gtatggtatg tatataatga ccctaaaagt ggagagagat atatctttca aggaaaagat
    21301 gttttacatt ttaaaacaag tcatacgcta gatggaataa caggattacc agtaagagaa
    21361 atattaagag ataccctaga aggtaatcta aatagtcagc aatatatgaa taaactatac
    21421 aagcaaggtc tgacaggcaa agccatacta caatacactg gtgatttaga taaaaaagca
    21481 cagagaaaat tagtatcgtt ttatgaagaa ttttcaaatg ggattgataa cacaggaaag
    21541 ataattcctg tacctatagg aatgactttg caaccattaa atataaaatt tacagatgta
    21601 caattttttg aacttagaaa atattcttct ttacaaattg ctggagcttt tggaataaaa
    21661 cctaatcata tcaatgatta tgaaaaatca agttattcaa attcagaaat gcagcagtta
    21721 agcttttatg ttgatacatt acaatttata ttaaaacaat atgaagaaga aacaacattt
    21781 aaactactta caaataaaca aatagaagaa ggttgtttct ttaaatataa tgaaagagct
    21841 attttaaggg ctgatacaaa aacacagatg gaaacattaa cagcaggtgt aaacaatggt
    21901 atctatactc ctaacgaagc tcgtgaattt gttgatttac cagaaaagga aggtggtgat
    21961 attcttataa caaatggaaa ctatatacca attacagaag ttggtaagca atatgagaag
    22021 ggaggtgtaa ataatgagta aaaaaaataa agataattta ataaatatat tacaaataaa
    22081 aaattctact gataaaaaag cagaactata tttttatggt gatatagtat ctagctcatg
    22141 gggagcttgg gaagaagaag accagtatcc agaatccata aaaaactttt taaagggtca
    22201 agagggtaaa gacctagata tttacattaa ttctggtggt ggaagcgtat ttgctggtat
    22261 ggctatctac aatatgttaa aaaggcatac agggtttaaa acaataaaaa tagacgggat
    22321 tgctggaagt atagcatcaa taatagcact tgcaggtgat aaaataatta tcccacgcaa
    22381 tgcttttttt atgattcata aagcgtgggg aattgtgcaa ggaaattcaa aaaaagttat
    22441 tgaatatgca agtttgttgg aaaaaataga taaaacagca ttagaaattt acaaagaaaa
    22501 tttaaaaaat gaaaatgata ttgaaaagat aaagcaaatg atagaagagg aaacgtggtt
    22561 aacaggagaa gaagcagcga aatattttaa ttttgaatta tctagtgaag tagatgcagt
    22621 tgcctgttct ggtgacatat tagataaata taataaaaca cctaaagtta ttaataacat
    22681 aaaagtaaac gacattgaag aaagaaaaaa taatttatta aaaagaatag aaagaatcta
    22741 gtggagggca aataatgaaa aataaaaata agtataatac aaacttaaat gtgtatatgt
    22801 cgactgatat aagagaagta aaagcatcta ttgatgaaaa tgtagaaaag ataaaaaatt
    22861 taattataga aaataaactt gatgaagctg aaaaactaac tgttgataca gagaagctta
    22921 aaaaaattta caatggttta ttagaattag aagatgaaga acttgataac ataaaaaata
    22981 aaataaataa ttctaaagca actaaaataa aaaatataga agaaaaagca aaatatgatg
    23041 gaaacttatt ttgtaaagta atagctaata ctttattaaa acagaaagaa aaaaatgaat
    23101 tttcagcagc aagggaacaa tttgaattta ctgactctga aagaatggct atttctgaaa
    23161 atatagacga ggatggcgga tatgcagttc cagaagacat ttctgtaaaa ataaatagaa
    23221 ggctgaaaga ttctgttgat ttatctactc tagttgattc agaacaagtt tatactagaa
    23281 gtggtcaaag aacttatgaa aaaagaatga aacaaacacc acttggaaaa ttatcggaat
    23341 ataattcaag tactcaaaca tatggcaaaa taaaagatac tgataatcct aaattagaaa
    23401 gaatttcctt taacttaata gattttgctg ggatgataac tattcctaat gacttgttga
    23461 aatttgcatc aaaggagtta gagaacttta taatagattg gatagttgat aaagtaagag
    23521 taacaagaaa catgataata ttaaatgggt acaaagatga tgatggtgat gaaattgggg
    23581 ggatattctc agatactacg aagttcaaaa aagtagattt gaagagtact tcaactatta
    23641 aaaactttaa aaaattgaaa aatgtaactt taaattctgt atttaaaaag agttctaagt
    23701 ggatagtaaa tcaagatggg tttaatttct tagatagttt agaagataaa aatggaagga
    23761 gctatttaca accagacact aaaaatgaaa ctgaatataa atttttaggt ttaccagtaa
    23821 tagagataaa taatgaaaca ctagaaactg aaacaattaa gagcgggtca gaaggaagtg
    23881 aaacaataac aaatgtatct cctattatat taggtgattt gaaagaagca tacaagatat
    23941 tccatgatgg caaataccaa ctagctacaa ctaatatagg ggctggtgct tttgaaacta
    24001 atacaaacaa agctagaata ataaacaagc tagatggctc tgtaaaggat gatgaagcaa
    24061 taataatagc taaattgaca ttgccagaag aacttgtata atgttagacg aaattaaagc
    24121 atatttaaga atagattcag atgatgatga taattggata gaaaaaactt taataccagc
    24181 aatcaatttg tattttaaaa atgcaggaat taatattgat gctgttagag aagaagaact
    24241 ttataagtta gctgtagaaa tgatggcttg tcattggtat gaaaatcgtg gagttgttgg
    24301 agatacaaaa ggaattgatt ttggattaaa gactatcatg ttacaactac aattttgcta
    24361 tgaagaggac aaataaaaat gaatgttgga gagctaaata gaaaaattac tatacaaatc
    24421 agagaagaaa gaaaggatga aaatggattt acaataaatg aatggttaga ttttaaaact
    24481 gtttattcta gtataaaaaa cttatatgga aaagaatttt tacaagctca agcattaaat
    24541 agtaaagcaa gtaagaaaat aaaaatcaga tatatcaaag agctagataa ttctataaac
    24601 aaggactcta gcattgaata tagagttgtt tataaaaata taatatataa tattttatac
    24661 atagataaca taaatgaagc taacaaatat atggaaataa tgctggaggg tgaataaatt
    24721 gggaataaca ttcgatttta gtaaacttca acaaaaactt aattccatgg aaagaaaagc
    24781 aggaaaagaa ttggttgata atgcaattga tgctggtgga agggtactag tagaagggat
    24841 gaaggaagaa gtaagagcaa atgtatatga tacaggagaa ttatataact caattggaat
    24901 gggtagaaaa aaaggttctg gtacaaagag gagtatagaa ataggttctc aatctaatga
    24961 tagggatgtc gtagctagaa atttttataa tgaatatggg actttaagag ttgtgggtaa
    25021 aaaacataat aaaagaagtt ttaataaaaa taaaaaaaag gctaatgaag cgataaaaaa
    25081 atctattata agtgatttaa agtaaggtga tacaatgaat ataaataagt taataattga
    25141 aactatagaa tctttagaca tagatacatt ttatatagaa gctagtaagg gaaaagataa
    25201 atattgtata tttagtattt ataaagaaaa tgaagaagat atttttgata acttacatag
    25261 ctcaataaaa tattatataa cagtaaatta ttggtttaga aatcctatag atgcagaact
    25321 ttataaagaa attaaaaaga aaatgaaatt gaataaattt aaaattgatg gttgtagaga
    25381 tttacctaaa actggtgatt actatggaaa gaacattgat tttatatata aacaaagaga
    25441 agagattaca atttagtagt ctttttttaa tataaaagaa aaggtggatt ataaaatgga
    25501 tgcttataca aagaaaatag tttatggaat ggataaaata catgtagcaa agattagtga
    25561 agatggatat gtgactcctg tagctatagt gggagcaaag gaagttgaag caaactttga
    25621 aattggagac aaaacaatat atgcagataa taaaggtatt tacaataata aaaagatatc
    25681 aaaaggttct ggtaaattag gtgtaatagg tcttacaaca gatgaaaaat gtttattggg
    25741 tggaactgaa aatatgagtg gtggatatgc tcttgcggat aatgttatac caccaaactt
    25801 ggcactatta tttgcacagg ataaggctga tggtggtagt ttgctaacag taatatataa
    25861 tgtccagttt aaccctgttt ctatagcagc agttacaaca gaggatagta tagaagagac
    25921 taaaacagag ctagaattta cagcactggt agggaaagat ggatattggt attatacaat
    25981 agatacaaca gacacaaaag ttgatgcaga tatgatatca aagttcttta cagaggttca
    26041 gttaccaaaa ataaaagcag attcagaaat atagaaaaat ctaaataggt gtcaaaatgg
    26101 gatatgaaga aaaaatctta tttggattag ataatataag agtgtgtaaa atgtcaaatg
    26161 attctatacc tattaaaata ctgggtgcaa tctctgtaga agttgaagta aaacaacaat
    26221 ataaatattt atatgtgaga gggagaaaaa gagtcaaaat aaatggagcg atagaatgta
    26281 caggaaagtt gagactatta ggcttaactt cattagaaca aaatttaatc tttggtcata
    26341 ttgaaagcga gggagttgct gttggagaaa acagtaactc tcctaattta aggttgttat
    26401 tcagtagaga aaaagcaaat ggacataaaa ttttctattg tatttataat gttgtttttg
    26461 acttgagttc tatagatgca aacacaacaa aagaaacaat gtcagaagat gtggtagaga
    26521 ttaattttga agggttaaaa gatgataata caaacttaac ttattattca atagatacag
    26581 aaacatgtga caaaaatgtt atagataatt ggtttaaaaa gatacaatac cctaaagagg
    26641 tgaaaagatg aatggaaata aaatggaaat aaaaatgaat ggtgttgttt atgaagctaa
    26701 acttgatatg ggagctttag ctgaaataca agattttttt agaaagaaaa atgatttttt
    26761 aaagcttcca gagataattc gaggatactc agaagaaaac tttatgatta taaatgaaat
    26821 aattatacaa agtattcaaa gatgccacaa acaattaaag cgtgatgaaa tactagataa
    26881 tatgttatta aaagatatag gtaagataaa agcttatgca ggtgaattaa taataaactc
    26941 gcttcctaaa gatgataaaa aaaaagaaaa ggaatagaga ataaaaaggt tgaagattgg
    27001 gattttgaat atcttcaata tttgtggtat acagttttac agcgtagaga agaattttgg
    27061 gacattactc ctaaaaagct atttgctcag ttagatgcac ataaaaaata taatggagta
    27121 aatgaagagg tagtaaagca agaaacagtt gatacaactg agtttatgta atggggtggg
    27181 caaatgtcag aaactattga gaaactagcg gtcgaattag ctcttgaagc tggttcattc
    27241 tctaaacaga tttctagtat aaataaagaa ataaagaatc tagaaagaga ttttaaaagt
    27301 gcagggaatg gaactaaaaa ctttgaaaat agttttgttg gattagatgc aaagattcaa
    27361 aagaccgcta gacaaattga tttatataat aaaaaactaa ttagtcaaaa acaagaacaa
    27421 gataaactaa aaagtacatt aactgaacaa aagtcaaaat tagatagttt agaagctaca
    27481 cttggcaaag gtagcaaaga gtggcaaaaa caagctcaac ttgtccaaca aactagctca
    27541 aaattaaatc gcttaaattc tgatgttaag caaactgaat ctactatcaa taagttaggt
    27601 acagagttaa atcaatcaac tagagcattt tcaaatcttg gtaataaaac acaaacaata
    27661 gagcaaaagc ttgctaatgt gaataggcaa accacactta cagaatcaga atttaataaa
    27721 ttaggtgctg aattaaatca atcaggtaca tattttcaaa gactaggaaa tgaaatgcaa
    27781 caattaagtg caaaaattca gtctaataaa gctatgctaa gtatttatga atctgaaatc
    27841 agaaaattaa atacaagttt aactcaaaat aaacaaacac atagccaact gaaaactgag
    27901 attaaccaga ctagaaatgc actagaacaa gcaaaaagta agtttggagc aaattcaaca
    27961 gaagctcaac aattacatgc taaattatta caattaaaag atgcttataa taaaagtgaa
    28021 catgaaattg aacagtcaaa tgctgcacta gacagatatc aagctgaaat aaataacaca
    28081 agagctgata taacaagact atcagctcaa ttaagacaaa tgccatttaa tactatgggt
    28141 caatctatgg tatcagcagg gcaaaaaata aaaggtgttg ggcaaagttt aggaatgtat
    28201 gtaactatgc cacttacaat gcttggagta gcagcatcaa gggcaggagt taattttgat
    28261 acaagtatgt ctaaactaca agcaacagca ggaattgcag ataaaagtag tgtatcattt
    28321 caaaaattac aagaaaaagc gcaagacctt ggagctagaa cttcattttc agcaagtgag
    28381 gcggctgatg gacttacata tctagcactt gcaggttggg atgtagagac atctttatca
    28441 agaatagaac cagtattgag agctgctgaa gctgggggta tggatttagc attgtgttct
    28501 gatttggtta cagacagtat gtcatcggca gggattgcaa gtaaagattt tactaaatac
    28561 ttagatataa cagctcaagc acaaagaaag tctaatacaa gtatgcaaca gatgttagag
    28621 gcttatgttg ttgcaggagg tatgtttaaa aatttaaata tgccattaga aaaatcagga
    28681 gcattattag gagtattagc taatagagga acaaaaggct cagaggcagg aaatgctatt
    28741 atatcagtat tctcaaattt aataactgag gctggtcaag caggtaaagc attagaaaaa
    28801 ttaaaaatat ctttatttga taagaagaca gggaagcaaa gagatacaat tgaagtatta
    28861 aaagaaatgg ctcaaaagct tggagtaaca gcagatggaa cttctaaatt gacagaagca
    28921 gagcaagcac aatatgctgc aatggttgga ggcaagacgc agtatgacag tttaatgaaa
    28981 atgttggcag gagttagtga tgagtatgat gatttagaaa ataacctaag aaattcaaaa
    29041 ggttcattaa tggaagttgc caaaacaatg aaagataatt taggtggagc aattacaaat
    29101 atgaaatcag ccttagaagg tgcaggtata caagcattta aggcaatgga gcctgttctt
    29161 gcgagtttaa tagaaaaaat aacacaactt tcaaattggt ttactaatct tagtgaatct
    29221 tctcaacaat ctattgtgaa gatggcagct atggcagcag ctttagcacc aatccttatt
    29281 gcattcggac aattgattat tgttggagga aatttaacgc ttattatagg acatataaaa
    29341 gcagctatga cagctacagc aggaacatca acaagtttat taactaaatt aggaaatcta
    29401 actactaaat tattttcttt gcaaggagct tttgcattac ttgcagtcgc aggtattgga
    29461 gtagcggtaa aggctttaca tgattatagt gttcaagatg gcaaattata tgaacaaaga
    29521 aagaaaaata tagaaagctt agagagagaa aaaaaaggat atcaagaagc aaaagaaaag
    29581 ataggttata tagcaaaaga atatgataca ttaaaaagta aatctaagtt gagtaatgaa
    29641 gaagcagaaa gactaaagga gttaacgaaa caaatagctg atttaatgcc agagcttgta
    29701 agtggttatg atgaaaatgg aaatccaatt ctaagtatga aaggctcagc agaggagtta
    29761 tgtttagagt tagatagagc tatagaaaaa aaagagcgtt taatcggatt tgataaacaa
    29821 gataatgcta aaattgcgat ggaaaaacag gctggaaaac gtgataagga tggaaataaa
    29881 gttgtaggta aagcagcgga ttctttgcaa acagatatag aaaaagttaa aactgtacaa
    29941 caaaaatata atgctgatat ggctaaacta gagcaggaag gtgcagtttt aagaggtaaa
    30001 attagaaata cagagggaaa agacagagaa aagtatttac tgaaatacaa aaaccatcta
    30061 agagagaaag agaaagttac acaggatgca caaaaaaata atgaaagaga tatagaagca
    30121 gctaaaaaag ttgcacaaga agttgaagaa ggtatatttg ctagtaccac tatgggaagc
    30181 gtttttaaat ctagtaaaaa taatgatgca aagaaacaat tcaatgaact caaaggtcta
    30241 ttagattttt ctggtataaa gacagatgaa caatttgcaa aagctgaaat atctatgtct
    30301 aaattattta aatcagcttc ggatggtaaa ataaatttag agggtgtaaa gaaacaaata
    30361 gaagatgcaa atacagcatt atcaaaagat ggagacttat cttcatataa cactaagatg
    30421 caagaactag caaagacaat agcaacagcg acagggacaa agtcaagtga ttggatatca
    30481 ctattaactt cattagataa agaattttta agaacaacag actctacaga tatatttttg
    30541 aaaaagttca atagaactag acaagaatta gaaagtggtg atagtctagc tgttgcagct
    30601 caaagacaat ttgacgaatt aaactcagca atagaaggat tgcaaataac agaaaataaa
    30661 gatgttaatg tacagactgt aattgatttc acaaataatc agaatatacc agaagatata
    30721 agaaaattta caagtagttt aattaagaaa gatgctaatg ggaatataac taactcagaa
    30781 gaggtaatta aatttacagc agacttgcta tttgagttgc aacaagaaaa accagactgg
    30841 aatattttac aacaagaagc agataagcta tttggaaaag ggaaggtaaa agtaacagaa
    30901 gatttagaga taactgctgg agagatagat tcatctaaaa ttgataaaaa taacatagag
    30961 caacaagtga aagacaagtt tagcaaagat aaagttacaa taaaaattaa tacagctatt
    31021 gaaaaaggtg aaattgatac aagcaaaatt ggcttggtag atgaaatatt taataatatt
    31081 aatgctacaa aagaagtaaa aactaaattt atcttagaaa atacggatgc aattaatcaa
    31141 gccaaaaatt atgaagaatt tctgaaaaat tttaaagata aggaatatct agctaaatta
    31201 ggaataaaag tagaaggtaa agaagaaaca aaacaagcaa ataaagagtt tgaaaagaat
    31261 aatggtaaaa catcaactca gaatgtgaaa ttagaaggtg ctgaacaggc aaaaaaagat
    31321 acacaagagc taaataagga aactgacaag gtggatggta aggtagttga gacaaaggtt
    31381 aataacgagc aagtagaaga aagtgtaaaa gatattaacc agcttgtaga gatgtctaaa
    31441 aaagttgaag atggaaaata caagattgat gtacaagcaa atactacaga tgcagtaaga
    31501 aatttagagc tactaaaaaa caagatgaat gaagttatta aatcattcgc agggaataaa
    31561 aaggttgttt tttcagcaga aacagaactc gcaagtaaga atgtaacagg attaaaaaaa
    31621 aatatttccg attatgataa gaagaatact aataagacaa agaaaactac ttttaagaca
    31681 gagacagcac ttgcaagtaa gaatgtaaca ggactaaaaa gcaatgtatc tgactatgta
    31741 tcaaagtatg gaaataagac atttaccacg acatttaaag ttgttacaaa caaagttact
    31801 acaacaagta ctagtggaac aaataatagt ggaggtactg acgaacaatc agaagatggc
    31861 agaaaatcta taccaattaa tttgaaaaga gttgaaactc caacaagaaa agtacctatt
    31921 aggtcaagtg taccattatt aagaaaaaca gcagaaactc caattaatat gggtaatatg
    31981 ggagattctc taaagtataa tgtcaacctt tttcaagaat tagaaaatag gatatcagca
    32041 gtaaataatg aattaacttt attagataag aaagccgaaa aagcaactgg aaaagaaaaa
    32101 ataaaacatt tacaaaaaca aaatgaattg tatgaagagc aacaaaggct tcaactagaa
    32161 ttacaagata agatgctttt caaacaaaca gttactaaaa gtaaattaga aggatatggg
    32221 ttacaattca ataatgaggg caatcttaaa aatgcagaag aagaactttt aagacgtgaa
    32281 aaaaaggctg ctgaattaga aaaaaaagca aaagaattat cagatagagc tagtaatgaa
    32341 aaaaatgaga agagaaaaga agcattagaa aaacaagcag aagcagcaca gaaggcttat
    32401 gataaagaaa aaacaagctt agatgatgta aacaaatata ttgatgaata tataaaaaca
    32461 accttaacag atattccaaa atgtatagaa gaatgggaag aattaaacaa aaagaaaaaa
    32521 gaaaatatag atattacaga agagttaaac aggcaacaaa aactattttc aaaaaatagc
    32581 catatcaaag aacttgatat gtataaagat ttgtattcag atgaaataga tataatagaa
    32641 gaaaaaataa ataatgcttc tggttctgaa aaaactgatt taatagaaga aaaaataaga
    32701 ctgatagaga agcaaaagaa agtacaacag gatttaatta atacatataa aagtgctata
    32761 aaagtttatc aaacagattt aagtaaattc ggatttcaat ttgatgataa agggactata
    32821 aaaaatcttg atgatatact aaataaatat caagatagtg aagatttaga aaaaataact
    32881 aaattggtag atgaatactt aactatacaa agagataaat taccagatgc agtaaaagat
    32941 tgggaaaaac ttagcacatc tattaagaat gcttataaag aacaacttaa tatagctaaa
    33001 gatattgaaa accaaattac tgatatatat aaaaagcaac tagaagaaag aaaaaaactt
    33061 atagatgaag aattaaaaaa gcgtacagat gctttgaata aagaaaaaga agcttataat
    33121 gatgctagaa aagaagctga ttatcagaat caagaggatg aacagttaca aaagataaag
    33181 gatatagaga aaaatcttga attagcaaaa agagatacaa ccctttctgg tcaaaagaaa
    33241 gttcaagagc ttataaaaca attaaaagaa gaacaaaaga acttagaaaa gatggttcaa
    33301 gacagaatcg acgaacaagt aaatgatatg ttcgataaag aaaatgatag gcttgagaat
    33361 gaagcagagg gtgcggttaa ggatttagaa gaaaagtttt ctgatagtaa aataaaagaa
    33421 ctgataaaag aggcactaaa aagtggactc tttgaagata tagatggtca agttaaaaat
    33481 cttcaagatg ttatgttaaa attcttagat gattatggag atggtctagg tataacagga
    33541 gagctaataa aagatgaatt agtaaaaaat ttagaagttg ctacagatgt tgctaaacaa
    33601 tatgctgaga taatggaaaa tttgaattta ggcaaaggtg gaagaagcat aaattatcct
    33661 aatgtagatt attcatctga aagatataac ccacaacaaa ggagtatcaa taatcaaaac
    33721 acacaagaaa ttaatataga gtttaatcaa ccattggtag ttattcaagg tgatgtatca
    33781 agaaatacaa tagcagactt acaaaagtta agtaaagata taaaaaatag tgtggttgat
    33841 gagataatta gaaaaatgaa gaggtgatta aattgtttgt atcagagcat tttatgtttg
    33901 acaatatatc atcaagtgaa aaaggtgtaa tatcagttac acaagactca gatgtattaa
    33961 atgagtatgg ttttatatat tcagaggaat tagaaataga taatacatat aataataatc
    34021 cttactatta ttcaaaaagt gacaaaagta cagaagatat atatattaat ttatgtagag
    34081 tagataatat gtataatcct atagaatggg atgattatac aattgaagat atatatagct
    34141 ggcttataaa aaaggatttc aaaccgtttg tatctgatga taatgtggaa ttaacttatt
    34201 atttaaaagt gaagaagata gttaaaaaat ttaacattga taaaaaggga ttgttagaaa
    34261 ttacttttca accatataca aattatagtt atagaaagtt aaaaaaagct gttactataa
    34321 aaaagaacag agaggtgact gtaactaact acagtaatct tgatactaac tatgcaccta
    34381 ttttagaaat taaaaattta agtgatgaag atataacagt agaaaatata actattaaat
    34441 ctgaacgctt ggaaatagca ggtctaaaat tgaatgaaaa aataattata gataacctaa
    34501 tgtatactgt ccttgatgaa aataaaaaca atagatttaa tttagtaaat agaaaatgga
    34561 ttgaattaaa aaagggagaa aatacattga aatttactgg aaattgtgaa gttattataa
    34621 atgctgaata tcctatagcg aggtaattta tgaaaattaa tcttaaagaa ctaaaaagag
    34681 attatgaaat agttttatgt aaaataaata aatgtgctgt tggacagatt aatattagat
    34741 ttattgatac attaagtaga agtatagata gtatggatga gatacaattt acaattccta
    34801 aatttatata tgatagaaat gggctaaaaa atataaggta tgtattatat gatgaaataa
    34861 aggaagaacg atttatttgt ttagatgata gagagtattt tgttataaag gaaatagaaa
    34921 ttaatgataa taaagataaa atagtcaaag catattcagc tgaaataaag ttatcaaaaa
    34981 tagatataaa tatagaagat gtagcaatac aattattttc agatgataaa gaaaatggag
    35041 taataagttt aaacaactac ttaaaacaag aaacatcttg gtctattggt catgtggatg
    35101 atgtagttgc atatgaaatg aatgaacatg gagataaagt tgaaaaatta agaatacaag
    35161 agagtgttag tagtaattgg catgattttt ttattaaaga tatcaaggaa gagttttcat
    35221 gtgttgtgca gtttgacaca tataataaaa aagtcaattt gtatgatata gatagttttg
    35281 gagacaatat tgagttagtt ttaacttatg ataattacat aaagtctaat aaaaaaacta
    35341 atagtacaaa tgatattgtt acaagattaa aattaattgg aagagaagaa atggacataa
    35401 taagtgcagt acctactgga tatgaatatt tagagaatta ttcgtatttt ctagaaaatg
    35461 gggaaatgag tgaaggctta gttaatgcaa tgatgacata tgaagaaatg gttgctgtta
    35521 gaaaaaaaga gtggtcaaaa ttggttgaaa taaaaaatac caaggaagct gagagactta
    35581 aaaaaagtaa taaatggcag atgattattg ctaatattga gatatgcgaa aaaatgatag
    35641 tatcttacaa aaatgctaaa gacgataaaa atgtagcatt aaaacaaagt gaacttacta
    35701 agttaaaaga tgaggagact atacttgaag ttgaaataaa aaggttagaa caagaaataa
    35761 aagggcttga agatagcata ataaatataa atatattatg taaaagagaa acagcaacag
    35821 accaagacgg acatttaata tttagctatg aacttttaga agaacttaaa gagtttatat
    35881 attgtgatac tttttcaaac gactcttttt taaatgttga tgattttgtt aatgcaggca
    35941 aaagggaatt ggatttaaag tgtaaaccaa caacagttta ttcaatagat gttgttaatt
    36001 ttttgcgtag aattttagat acaggattta ggcaacactt tcaaggatgt ttaagtctag
    36061 gagatataat agttctttat aataatgtag agtgttatga agaacatgta tattttgttg
    36121 gttatacaca agattttaaa gaggataaac taaatataga attatcaaat aagaaattaa
    36181 aaacagataa tacaagaacc atagcagatt acttaacaaa atctaggagt accactaatt
    36241 tgttaaataa gaaaaaatat ttattgaata aacaaaaata taataggatg aatgttccag
    36301 agagggtgat gtgatggcta taacagataa tagctataca aattcataca tccgtataac
    36361 tggatgttta gttaattatg ataaagagct gtatcaagta caagatgatt ttacaaataa
    36421 aaaatatgta tattggaaca gagaaaatcc atataaattt gaattttcta ataaaatgct
    36481 tgataaagga aatactagat ttttaatcat aataaatgat aatggtgtcc atacagagta
    36541 taaaaattat tctgatattt ttagtataac ttttgatgga gattcagtta aaaatataca
    36601 gaaagaaatc tatgcattat atgagaatga taaggaattt ggtgatagat ttgtagctgt
    36661 tgagaaggat gttgatggaa ttagtcaaac agtaggatta atacaagaag atacaaatca
    36721 tatgaaagaa aacatatctt ttatagaaca aagagctgat aatataaatt tatttgtaaa
    36781 agaggttaca aaaaaattta ataactctca agaagctatt aaattaagag aagaagtgaa
    36841 taaaactata attaaattaa atgaagattt aggtttattc agttctaaca tagtaggcta
    36901 ttttgaagat gatgaaataa cagatataga aaaagaacaa atatatactc agatagagtt
    36961 aatggagaat gataaagcaa atgtatatat tcagttacaa aagattattg ataaatgcca
    37021 gagtaataat gacaatgtaa gtatatcagc aataaatagc tcaaagactg ctttagataa
    37081 tgcacataat aatcttaaat caattattga ttcagttgtt gtagatagta tagtaactaa
    37141 ttctgagaga gtactagtta taaattgttt ttcaaaatat aatcttagaa taaatgaatt
    37201 aaaaaatacc ttagatgtta tctttttaaa agaagcagga ggaagtgttt cagaagaatt
    37261 tgcaggtatt aatgttaaat ttgatgaagt aaatttaagt gtaaaaaaaa taaattcaga
    37321 tattggagaa ataagttctg aaataaagct aatgaacgat gaaatattgc tgaaagttaa
    37381 tgaaggcgat ttaagttcta tgatagaaca aagatacaat agtgtaaaga tagcatttaa
    37441 taaaataaat tctgctgcgg ttactataga ctatagagga ttaacagttt tgaatggctc
    37501 tattgcttgt gattgtctta caacaccagc tggtcatgaa cctattattc gactatttga
    37561 ggatagtagt gcaagtataa ctctagatgc aagagaaagc aatggagctg taaaaggaag
    37621 tgcaataaga ctaaagtata atgaaaatta tttgtttata aatcgacttg gagcaaacat
    37681 atttgttgat ggtgaggtaa gactacaagt gaaagaagat gatgctttca taaagtgtgg
    37741 gagtgcaaga ttttgtttta ctaatgaccc attttcattt tttccagacc aaagtcgaac
    37801 tgacctagga caaagttata atacttggag aaacgtctac tgtgatactt taaggtgtga
    37861 tgatgttaga agcacctcag acagtaaatt caaagaaaat attaattata taagtattac
    37921 aaaaggaaag atatttagaa ggtcattttt aatggatacg gaaactcctt tttcagattt
    37981 tttgaagaat gaattaaaag tagctacatt taattataaa aactttagtg aagaagatgg
    38041 aaacaatcaa caaattggat tcatagcgaa tgatataaaa gactcaaaaa ttggaagtat
    38101 gtttatatat aactatggtg aagaaatagg gttaaaattt agtatggctg gatacataac
    38161 tgtcatagca gcagctttgc aagaagaaat aataaaaaga gaagaattag aagttaaaat
    38221 aaatcagata gagagtgttt tgtgcgaagg ggtgtaaaaa tggaagtaga cttaaaaata
    38281 atgtttgaaa atgcgttaga tgaaataaaa aaattaacaa cagatgtgtt gctgtataaa
    38341 acattgttaa tacaaaaaga aaaagatata gaagataacg agaagaatat agaaatatta
    38401 ggtaaaaaaa ttgaagaatt agaagaaagt aaaagtaaat aaaggatgtg gaggaatgag
    38461 agaatatgaa gtaaaggaat atttcttaga gatagatttt tcctgttatg agacaaaaaa
    38521 tgtagttaag aagctaattt ataatgaaaa tgatataaat actgctttta tcaatataca
    38581 gttaaaaaat gatggtaaaa taataaattt aactgactat gaagttatag ctaatatatg
    38641 gaaaaatata ggaaataaag tccagaatcc ttgtaagata ttaaatggag agcttggaga
    38701 gatagaggtt ccgctaacta gacaatctct aaaaggagct ggtgtaaatc catttacaat
    38761 ttcaattgtg aatggagaac gctctttgga gtctccacgt ttctattata gagttgaaga
    38821 agctattgtt agtgatgatg atattgaaaa tgcggatgaa tttggtgttt tagtattatt
    38881 aattagtcaa gtaaaagaag ttttaaaaga caatgatatc ttagttacta gagttgaaaa
    38941 tttagaaaat ttaatagaag agcaagagga aataagaagt acacaggaga caactagaga
    39001 aactaatgaa ttaactagag aaactaatga gaaggaaaga aaaataaatg aattaaccag
    39061 acaaactaat gaaacgacta gagagtctaa tgaggaagaa agaaaaacaa gtgaaacatc
    39121 tagaaaa
//
LOCUS       DAEORM030000036        38781 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.036, whole genome shotgun sequence.
ACCESSION   DAEORM030000036 DAEORM030000000
VERSION     DAEORM030000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 38781)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38781)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 38781)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38781
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.036"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            175..1284
                     /gene="tnpB"
                     /locus_tag="KRH23_002365"
     CDS             175..1284
                     /gene="tnpB"
                     /locus_tag="KRH23_002365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family element RNA-guided
                     endonuclease TnpB"
                     /protein_id="HHS5225643.1"
                     /translation="MEKACKFRIYPNKKQQELINKTFGCCRFVYNKYLAKRIEVYKND
                     RETFTYKQCSSDLTNLKKELKWLKEPDKFSLQNALKDLDNAYKKFFKEKAGFPKFKSK
                     KINRFSYKTNFTNGNIMYCGQHIKLPKLGMVKIRDKQVPQGRILNATISKEPSGRYYV
                     SLCCTDVDIEVFENTNNQIGLDLGIKEFCISSCGEFIENPKYLKKSLNKLAKLQRELS
                     RKTIGSLNRNKARLKVARFQEHIANQRNDFLQKLSTKLIKENDIICIEDLQVKNMIRN
                     RKLSRLISDVSWSEFIRQLEYKANWYGRKIVKVGKFFASSQICNKCGYKNEEVKDLNI
                     REWICPSCNETHDRDINASINILKEGLRLITIQNK"
     gene            1417..2922
                     /gene="ade"
                     /locus_tag="KRH23_002366"
     CDS             1417..2922
                     /gene="ade"
                     /locus_tag="KRH23_002366"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: protein motif:HMM:TIGR01178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000034 - adenine deaminase activity
                     [Evidence IEA];
                     GO_process: GO:0006146 - adenine catabolic process
                     [Evidence IEA];
                     GO_process: GO:0006168 - adenine salvage [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HHS5225644.1"
                     /translation="MSPGFIDAHMHIESTMVMPIELSKKLLKSGTTTIIADPHELVNV
                     KGASAIDFLLESTKDIPLNVYIMVPSSVPATSFETNGVGKFSAKDMESYVNNPRILGL
                     GEVMCFNDVINSENEILDKLELFKNKVVDGHAPNINGKSLQTYVCAGIENDHECITFD
                     EVYEKLRAGLKILIREGSAAKNLKSIVSGMLKHNLPIEEFMFCTDDKHLDDIEKQGHI
                     RWNIKCAIDLGMEPVRAIKVATYNSAKAYGLRKIGAIGAGYKADIVVLNDLDKMEVDS
                     VYKDGNLVNEEMFSNYNYEIKDKELLNTVKFKYINKEKIQLKVSEKNYVMEIVPYQIL
                     TNKVYESLPCADGYFVPNKEYSKLCVVERHRMTGNVAVAPLKGFGIKNGAIATTVAHD
                     SHNIIVAGDNDDDILVAINYLKEIQGGYVIVSNGKVLAHLSLQVAGLISTFTAEEVQE
                     ITDNMLEIARKMGVPEYVDPFITLSFMALPVVPQIRLTDLGLFDVEEFKFI"
     gene            3274..3738
                     /gene="bcp"
                     /locus_tag="KRH23_002367"
     CDS             3274..3738
                     /gene="bcp"
                     /locus_tag="KRH23_002367"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016209 - antioxidant activity [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-dependent thiol peroxidase"
                     /protein_id="HHS5225645.1"
                     /translation="MLSIGTKAPEFTLEDKDGNKVSMSDFKGKKVVVYFYPKDNTPGC
                     TRQACAFRNAYDGFKKEDIQVIGISKDSIKSHQKFAEKHELPFILLSDPDLVAIKAFD
                     VWKEKKMYGKTALGVVRATYIIDENGIIEKVFEKAKPDTNAQEILEYLEKQE"
     gene            3748..4491
                     /gene="yaaA"
                     /locus_tag="KRH23_002368"
     CDS             3748..4491
                     /gene="yaaA"
                     /locus_tag="KRH23_002368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HHS5225646.1"
                     /translation="MIIMLSPAKNMKNIEVFDRDLSLPCFIDNTKEIVENIKTFGIED
                     FKNKMKINEKLAVLNKNRFESIKFDRLGNPAILTYDGIQYKNIEAENFTRKDEEFANS
                     CIRIISGLYGVVKPYDSIYEYRLEMQTKLRVGEFKNLYEYWGNRIYKELIKEKTAIVN
                     LSSNEYSKSIEKFIKDSDTYITCTFKVNKNGILKVESTQAKKARGMMTKYIVKNRIRD
                     IEELKKFNLEGYKYKENLSNNSEYIFVKE"
     gene            4589..7276
                     /locus_tag="KRH23_002369"
     CDS             4589..7276
                     /locus_tag="KRH23_002369"
                     /EC_number="7.2.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005388 - P-type calcium transporter
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006816 - calcium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="calcium-translocating P-type ATPase, PMCA-type"
                     /protein_id="HHS5225647.1"
                     /translation="MKKRKEWSSKMENHKQMPWHSRATHEILESLDSSEEGLTDTEAE
                     KRLKENGLNELRKKPPRTTLQMLWSQITDAMVMILIGAAILSLIFGEFTEAFVILIIV
                     TVNAVIGIVQEKKAESSLEALKNMNSPTARVMRDGEENVIPASNLVVGDIVFLEDGAM
                     VPADLRLIETSSLKIQEASLTGESVPSEKDADTILPKECVLGDRSNMAYTSSIVTYGR
                     GVGVVVATGMDTEVGNIAHLLDSQDDFDTPIKRKLNTVGKTLSVIGIIVCVVIFAIGA
                     FYQRPLLPMFMIAISLAISIIPEGLPATATIVMALGVQRMAKRNALIRKLPAVETLGG
                     ATVICCDKTGTLTLNKMTVTHIAVNGDFESGKVTSIDTASEKHPLVYKEIVYAGALCN
                     DACINPDKTDEILGDPTEGALIFMAKKFGIDQEALEEEYPRVFEQPFDSDRKCMTTVH
                     NIDEKIIAYTKGAVDEILDLCTKILTSKGERNITEVDKKNIHELCLNMSKNALRVLGF
                     AKREISSIPKEDSENIEYDLTFIGMVGMIDPPRTEVIDAVSTCKEAGIRTIMITGDHK
                     VTATTIAHELGIWSEENTVISGDELDNLSDDELDEAVKNTTVFARVSPFDKLRIIQSL
                     KRIGEVPAMTGDGVNDSPALKSADIGIAMGISGTDVAKDSSDMILMDDSFTTIAYAIK
                     EGRRVYRNIQKVIQFLLVGNIAEILTLFVAILLNWDTPLLAVHILWVNLATATLPALA
                     LGVDPPSRNIMKHQPVKSTTLFEKNLIQRVVTQGIFVAIMTILAYKIGLNIENHSVGQ
                     TMAFCVLAFSQMLRAFSQRSNTDSMFNRNNGKNPFLLISFLTSAFLIAVILFVPVFRN
                     AFNLTVLNNLEWLITIVLAIMSVIQVEVGKIIKRKKLKK"
     regulatory      7330..7432
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            7542..8807
                     /locus_tag="KRH23_002370"
     CDS             7542..8807
                     /locus_tag="KRH23_002370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0019346 - transsulfuration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase family
                     protein"
                     /protein_id="HHS5225648.1"
                     /translation="MYNKETICVQGNYKPGNGEPRVLPLYQSTTFKYSSIDQLAELFD
                     LKVDGHIYSRISNPTIQAFEEKISLLEGGVSSVAVSSGQSANMLAVLNICKSGDSILC
                     SSKVYGGTFNLLGPSLKKFGIDLISFDLDSSEDEIVELAKENTKVVFAETLANPTLEV
                     IDFEKIANVAKRINVPFIVDNSLASPVLCNPLKYGANIVTHSTTKYLDGHASSVGGII
                     VDGGNFNWDNGKFPELVEPDPTYHGISYTQKFGNAAYATKARVQLLRDYGNCLSPFNA
                     YLTNLNVETLHLRMERHSENALKIARFLEKHENVDWINYPGLEDNKYYENAKKYLSRG
                     CSGVLSFGVRGGLENAKKFVEKLQIASLVTHVSDVRTCVIHPASTTHRQLTEEQLIAS
                     GVLPSLIRLSVGIENVEDLIADLNQALNF"
     gene            8837..9727
                     /locus_tag="KRH23_002371"
     CDS             8837..9727
                     /locus_tag="KRH23_002371"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004414 - homoserine O-acetyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0008899 - homoserine O-succinyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0019281 - L-methionine biosynthetic process
                     from homoserine via O-succinyl-L-homoserine and
                     cystathionine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HHS5225649.1"
                     /translation="MALILPKGLPVINKLLDEGIDVIYKEDFKKELKYEENIDTKIAI
                     LNLMPIKIDTELDLLRRIDKTGFNVSVEFIKISTRESKRSCNEYVKEFYKTFDEAKGE
                     YFDGFIITGAPVEQMEFEEVDYWNELEEIMDYSKRKTKSTLYICWAAQASLYKYYNVK
                     KLPLSQKCFGVFKHKVDKDSKIVDGFENEFFAPHSRHTTVNIEALKENKELSIVSHSK
                     EAGPYIITNSRDVFVMGHSEYDKYTLDKEYKRDINKGDKISIPQNYYINDDPSEEPTV
                     KWKKHSELLFRNWIKNYLIQ"
     gene            10216..10659
                     /locus_tag="KRH23_002372"
     CDS             10216..10659
                     /locus_tag="KRH23_002372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HHS5225650.1"
                     /translation="MDEMSFKKELLELTRDINMKFTTLLSDFYQPLGITAVQALILSE
                     LCEHGEKKISDLGKNLNMTNSNVSVICQRLEKNGFLNRIRDIEDQRIVKVKVTNKSLD
                     IQEHISSSIFDSYFENMTSEKLQDMEDIIEGLEKLNKLLTYIDCK"
     gene            10690..12507
                     /gene="ftsH"
                     /locus_tag="KRH23_002373"
     CDS             10690..12507
                     /gene="ftsH"
                     /locus_tag="KRH23_002373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HHS5225651.1"
                     /translation="MDEHKPQKRSALYYYTVIIIVVMFLNALIFPSLMDKKMVEIDYG
                     KFLTMLDTGKVKSVEIENNRIAINPSSSKDKNIYITGRMDDPELVDRLKNAKVEFTKV
                     IPKENSPLLSILLTWIIPIGILMLFGNLMMKSMQKRMGGNAMQFGKSNAKMYVSAQSG
                     KRFNDVAGQDEAKEALTEIVDFLHNPEKYKKIGAQMPKGALLVGPPGTGKTLLAKAVA
                     GEANVPFFSISGSEFVEMFVGMGASRIRDLFKQAKEKAPCIVFIDEIDTIGKKRDNGS
                     GLGGNDEREQTLNQLLSEMDGFDGGIGVVILAATNRPDSLDKALLRPGRFDRRIPVEL
                     PDLGGREAILKVHAQNVNVSSDIDYNAIARSTSGASGAELANIVNEAALLAVKSGRDI
                     VEQQDFDESVETVIAGYQRKGAVISDKEKKIIAYHEIGHALVAAMQKHSAPVHKITII
                     PRTSGALGYTMQVAEDESVLMSKEEAIDKITTFTGGRAAEEVIFNTCTSGASNDIEQA
                     TKIARAMVTRLGMSEEFDMVALETVSNQYLGGDTSLACSSDTAAKIDEEVFKIVKACH
                     KNAIEILENNIDKLHELANYLLEKETITGDEFMEILNLN"
     gene            12685..15387
                     /locus_tag="KRH23_002374"
     CDS             12685..15387
                     /locus_tag="KRH23_002374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HHS5225652.1"
                     /translation="MDRPNPDILLEKIKNEEEKLSRGQLKIFFGYAAGVGKTYSMLES
                     AQNLKKVGVDVVVGYIEPHTRPETLALLDGLEILPVKEIEYKSIKLKEFDLDAALERK
                     PEVILVDEFAHSNVAGLRHTKRWQDIEELLLAGINVYTTVNVQHLESLNDIVEIITNV
                     SVKETIPDKFLDTNTQLELIDVEPDVLLERFNEGKIYKKEQATRAKNNFFIKDNLVAL
                     REIALRKTAERVNKEVQMTRLSKGDVTVIPTSDTLLACISPSPSSAKVIRTASRISDS
                     TFAKWIALYVETPNTARLPFDEQKQLQNNLKLAKKLGGEIIVLHGENIIEQILRIAKL
                     RNVTKIVIGRNHSSNKRFSKKFKKDIVDKLIDEVDYIDIHIIPYKFASDVKYKPKKDK
                     SSIKSKFKISKVDFIKLIFITLMISILAYAVQSMGFIRENILLIYMLGVVLVSMWTKG
                     YSTGIISSVFNIVLLNYFFTAPLYTLSIADSNYIVTLVVFSIVGIITSTLTSKIQHEA
                     ETAAKREENTKMIYQIIKGFLRLSNKDDIVNKGIELLSLSLSRDVICYLNVDKHNKSK
                     LYKKNTNNKDKNDLDSEDEKAVASWVLSNSTVAGNDTDTLPGSKGYYIPIVGMNLTLG
                     VVGISCIDSKLDTEDISLIETIIAQMAIALDREILSEAKENTNLEIERERLRSNLLRA
                     VSHDLRTPLAGISGAVSTIIKNKGTIGQDIIDELLSGVYEDTQWLIRLVENLLSMTKI
                     DEGKLEVKKHSELVEEIISEALQKIKKRIENALIDINIPEQILFVPMDAKLIEQVLIN
                     LIDNSLKYSKEDCKIEINVYEKDDYVWFEVSDNGPGISKELKKHIFDRFFTGEEGAKD
                     SRKGVGLGLSICKSIIQAHKGEIMVENNKDKGSTFKFSLPKENE"
     gene            15421..16119
                     /locus_tag="KRH23_002375"
     CDS             15421..16119
                     /locus_tag="KRH23_002375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HHS5225653.1"
                     /translation="MSKKLILLVEDDKTIRKFISTALLTQDYDVKEAITGKEGISIAV
                     SYSPDVVLLDLGLEDMDGIEVIKAIRQFSNIPIIVVSAREQDRDKVEVFDAGADDYLT
                     KPFSIVELLARVRVAFRHSQVEAQQKDDVKSTFEVDKLLIDFDKRKVIVDDVEVHLTP
                     IEYNILSLLAKHHGKVLTHNFIIKEIWGSVIGNETKSLRVFMATLRRKIEKQPANPRY
                     IITEVGVGYRLNDE"
     gene            16476..17432
                     /locus_tag="KRH23_002376"
     CDS             16476..17432
                     /locus_tag="KRH23_002376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CorA family divalent cation transporter"
                     /protein_id="HHS5225654.1"
                     /translation="MYILNLNTRETIEDFRDKFYVAENSYLILSAPKNLKLLKETLDI
                     DEITFNDCLKFDEITKLDLFDNYDFLSLNTFELRDGEAVIEEVNMYLSDNFILVVVNE
                     EHFLFEFVKNIILKNSQLEKNPVINLFKINYLILREVIKNGFESLEKVEELILQIEDE
                     MMDNINKNHVSRISDVRGLTRIIVKNTRPLLYIGDRIVKENIRYLKYSNVKKYNLENF
                     QGIDFGIDKLYNFALSTRELADKLLDIYSSRVGEKTNNLITKLTLLTAISAPLTIITG
                     IYGMNFRYMPELNWIYGYPATLFFMLCIIFVGIIIFKIKKLL"
     gene            17609..17764
                     /locus_tag="KRH23_002377"
     CDS             17609..17764
                     /locus_tag="KRH23_002377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5225655.1"
                     /translation="MKGILKELTAKLYSFFYFMFWGFYFSAGYFFYKNICTSFLVRPY
                     FSDFEHK"
     gene            17894..18907
                     /gene="aroF"
                     /locus_tag="KRH23_002378"
     CDS             17894..18907
                     /gene="aroF"
                     /locus_tag="KRH23_002378"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003849 - 3-deoxy-7-phosphoheptulonate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HHS5225656.1"
                     /translation="MIVVLKMGADKNEVKKLIEAIGREGVEVNPIDGTELTVLGLVGD
                     TSKIDAKRIEANKVVEKVMHVVEPFKKANRKFHPEPSIINVNGMEIGSKKIAMIAGPC
                     SVETEDQIVSIAKDVKKSGAGFLRGGAFKPRTSPYAFQGLKYDGLDLLKKAKEKTGLP
                     IVTEIMSTQDIDIFEENVDVIQVGARNMQNFDLLKELGKTNKTILLKRGLSATIEEWL
                     MSAEYIMAGGNENVVLCERGIRTFETYTRNTLDLSAILAVKKLSHLPVIVDPSHAAGK
                     SWMVDSLSKAAIAVGADGLIIEVHNDPAHALCDGKQSIKPNEYDELISELKTIASAVG
                     REI"
     gene            18929..19993
                     /gene="aroB"
                     /locus_tag="KRH23_002379"
     CDS             18929..19993
                     /gene="aroB"
                     /locus_tag="KRH23_002379"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003856 - 3-dehydroquinate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HHS5225657.1"
                     /translation="MEEKLLVNLKENSYNIFIKKNILKNIGEEIKKIYFGNKIFIVTD
                     ENIAKLYLDKVKNNLSESGFEIKSLILKSGEETKSFNTLPKIYDSLLDFKLTRKDLII
                     TLGGGVIGDLGGFAAATFLRGISFIQIPTSLLAQVDSSVGGKVGVDLERGKNLVGSFY
                     QPKAVFIDPNVLLSLPEKFYRDGMAEVIKYGCIKDKTFFNKLLSLKNREEVMQHIEYI
                     IHKCCFIKKTVVEADEKDFGDRMLLNFGHTLGHAIEKYYNFTGYTHGEAVAIGMYKIT
                     LESEKIGITKKGTSELIKSILMNYNLPYEIELRDNKSIVDAISLDKKNLGDTLKIILL
                     KDIGESIIYNTTSKFFQEVR"
     gene            19993..21306
                     /gene="aroA"
                     /locus_tag="KRH23_002380"
     CDS             19993..21306
                     /gene="aroA"
                     /locus_tag="KRH23_002380"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003866 - 3-phosphoshikimate
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HHS5225658.1"
                     /translation="MGSLKIYPSKLSGDVKIPPSKSMAHRAVICSSLSNGKSRISNID
                     FSDDIIATIRAMTSLGAIIEKKEDILEISGIFSKEGILNRENQLNQPKLTIDCNESGS
                     TLRFLVPISLAFDGVKRFIGRGNLGKRPLDTYYEIFDRQNIKYSYKENQLDLIISGKL
                     KPDEFRVKGNISSQFITGLLFILPTLESDSKIIITTELESKGYLDLTLSTIKDFGVEI
                     INNNYKEFIIKGNQTYKARNYKVEGDYSQGAFYLSADAIGEDISILDLKEDSLQGDSE
                     VVEILSRMGMEILREGNKIKGITNGLNGTLIDASQCPDIIPVLSVVASLSIGRTTIIN
                     AGRLRIKECDRLHAINVELSKLGANIEEKEDSLIIEGVSKLNGGVEVWSHKDHRIAMT
                     LAIASCRCDKPIILKDFECVSKSYPHFFKDFKMLGGRIDEWNMGK"
     gene            21284..22363
                     /gene="aroC"
                     /locus_tag="KRH23_002381"
     CDS             21284..22363
                     /gene="aroC"
                     /locus_tag="KRH23_002381"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004107 - chorismate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HHS5225659.1"
                     /translation="MSGIWGNNLKISIFGESHGNAIGINIDGLPSGIELDLDNIDKEM
                     KRRAPGKNSISTSRNESDIPEILSGYFNGRTTGTPLCAIIRNSDTRSKDYGELKNLMR
                     PGHADFTGNVRYSGFNDYRGGGHFSGRITAPLVFCGAICKQILSQKGIEIGAHIKKIK
                     NIEDMSFDYVNISKQQLSNLQTLELPLLDLSKEEAMKNTIIDAKNQGDSVGGIIECAV
                     VGINVGLGNPFFDSVESTLSHLLFSVPAVKGVEFGLGFELADMYGSQSNDEMYYEGNQ
                     VKSKTNNNGGIIGGITTGMPIIFKVAIKPTPSISRQQNTVNIKDKKDDILYIKGRHDP
                     CIVQRAIPVIEAVTAIGIFDLMKGR"
     gene            22366..23562
                     /gene="pheA"
                     /locus_tag="KRH23_002382"
     CDS             22366..23562
                     /gene="pheA"
                     /locus_tag="KRH23_002382"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004664 - prephenate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0009094 - L-phenylalanine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HHS5225660.1"
                     /translation="MEDLTRYRNEIDNIDKELIQLFEKRMNTVLEIARHKMKNNTTIL
                     QKDREEKVLSRAVDNLDNKAYSQETVQFFNSIMEISRGLQKRLIDNDGEQKIEFSLDS
                     SNKKFDLSNVNKYKSLKDELNKKNILVGFPGKSGSFTEEALNKFFNKKISKKQFKEFE
                     DVFIALKNKEINYGIIPIENSSTGAISETYDLLRKYGFYIVGEECIKIDQNLIGIKDT
                     KLEDIKEIYSHPQGIGQCSEFLKQNSTWKLIPFNNTATSAELVRKLQDKTKAAIASKK
                     AASIYGLEIISHCINDITNNYTRFVVISNQIHIEEESNKMSVVFSVEHEAGKLYKVLG
                     YFAKNNINMTKIESRPMKNASWRYFFYIDFECSIYNAKVYDLLELIEHNTAYFKFMGV
                     YKNKTE"
     gene            23609..24418
                     /gene="aroE"
                     /locus_tag="KRH23_002383"
     CDS             23609..24418
                     /gene="aroE"
                     /locus_tag="KRH23_002383"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004764 - shikimate 3-dehydrogenase
                     (NADP+) activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0019632 - shikimate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HHS5225661.1"
                     /translation="MNFFGLVGEKLSHSVSPRIHKRVFEILNIESAYKNFEISKEDIS
                     KLDGAIKLLGIQGVNVTVPYKERIMKYLDFISPEAKRIGAVNTILLRENMLYGYNTDY
                     FGLDSMFKMANIDVQGKVAVILGTGGASKAALTYFIDSGIEKLYVSTRKKDDKKLLNS
                     KAILIDYEELKHIKGDIILNATPVGMYPNVGISPVSKSIIQNFDILIDLIYNPGETEF
                     LRIGNSMGKKTCDGLYMLVGQAIKSQEIWQDTKIDNSILDVIYNELKLEFL"
     gene            24430..24963
                     /locus_tag="KRH23_002384"
     CDS             24430..24963
                     /locus_tag="KRH23_002384"
                     /EC_number="2.7.1.71"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004765 - shikimate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HHS5225662.1"
                     /translation="MINKTKEKLILIGMPGSGKTTIGKLLAKEYNCSFCDMDDYIIQI
                     SQKSIAELFSEGEDIFRNYETQACRELSISDKTVISTGGGVIKKDVNMEILKETGIII
                     FIDRPIQKILEDININSRPLLKNGKDRLYNLYNERINLYKKFSDIEILNDKSLNNAVY
                     NITNAVSENFKFDFKEK"
     gene            24984..25823
                     /locus_tag="KRH23_002385"
     CDS             24984..25823
                     /locus_tag="KRH23_002385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HHS5225663.1"
                     /translation="MNIVIVGLGVIGGSFAKALKKAGYENVFGVDVDLETLKKAEKAK
                     IIKKGCTTGKELFKKADLIILSIYPRLVVDFLNNNKNFFKKGTIITDTTGIKETLIND
                     VLQIIPDDIDFIFGHPMAGREKKGIDFASEQVFNGANYIITPTGRNNIKNLELVENLI
                     LEIGFKRVKKLTSQKHDEIIAFTSQLPHVMAVALINSDEEGRDTGKFIGDSYRDLTRI
                     ANMNEDLWSELFLGNRDNLLKVIENFESEVNLVKEAIFNNDKNKLIEYFKKSSIRREA
                     LEK"
     gene            26091..27572
                     /locus_tag="KRH23_002386"
     CDS             26091..27572
                     /locus_tag="KRH23_002386"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0052621 - diguanylate cyclase activity
                     [Evidence IEA];
                     GO_function: GO:0071111 - cyclic-guanylate-specific
                     phosphodiesterase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="HHS5225664.1"
                     /translation="MKKNRLIAKNISIAFIVLFFFSVFTFFYVGNINRVLEYETNDII
                     TVTIAGWIILSFLFLGIIIYILYSKANSQKTIEKVAYTDFVTGYSNWRKFELDVTNLL
                     KKTSQNNKYAMVIFDIDKFKAINDIYGHKKGNLILKDIADTLNELTNINETFARVSAD
                     NFNILLTYNKKEDIINIIKKIMANNELVNLSFGIYEIKDKDLSVSVYSDRASLAKSSI
                     KNNSDVNFAFFNDKLREKLLLEDKIEKEMEYALESGQFVMYLQPKYNIKLDKFCGSEA
                     LVRWQYTEKEVIYPGDFIPIFEKNGFIRKIDMYILEQACKEIRSLFDKGISPLPISVN
                     FSRVDFFKKDFIENIVNICDRYKIPYSLIEIEITESSMFGDTDTLFNVSRNLQDIGFI
                     VAMDDFGSGYSSVNMLKNIPLNVIKLDRGFFVDDKDVDKSQIVIKSIVSLIKQLGIRV
                     VAEGIETRSQIEMLKKANCDIVQGYYFSKPLPIKEFEKLVYKI"
     gene            27605..31042
                     /locus_tag="KRH23_002387"
     CDS             27605..31042
                     /locus_tag="KRH23_002387"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0052621 - diguanylate cyclase activity
                     [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor domain-containing diguanylate cyclase"
                     /protein_id="HHS5225665.1"
                     /translation="MIRAKSLKNVLSIVLIFLFTIISFSDFAFKTNVQEEENSKINLR
                     EISLQSSNAIKIKLDSSLSFIKSVANMVSYFNTIDNSKIVPLLANISKESDFQRISIV
                     SPDGISHTSDGKIINVSKYQYFKKAIKGESNISEVVKSPIDGKDTFVIATPVFNKNNK
                     IIGVLYGSYYNDKLAEFIDITSFNSEGYIDIFESSGQFVLKSSHTNKLIKSSSNIYDI
                     FKKASFDDGYSYKKIYEDTKNNKSGFTSYEYKGENRYATYTPIGVNDWYVISVIPQYT
                     VRRNIDKINQLAFSLIFKVFLLFIMLIIYIIYKNNKSQKDILKANKEISSITNSIPGG
                     VQKCTLGETCNINFLSDGFIELFGYTREEIKTLFNNDFYSLIHKDDVERIKKEIFKQL
                     YKNKTIELEYRIITKNGNTVWVLDKGELITEPDGKEYFCCVTVDITRTKQLEQEMEQK
                     NLELEMISENVLGGIIITEFNDDFTIKYTNSGYLSMIGYTREQLENELKYKACNLVFY
                     EDRKKALESIQHQLNTKGIAVYQHRIRRRDGNIIWVSIKGRLIIDDDGIEKGIWILND
                     ITDLKNAEQKLKINEERFRIALKQTSNTIFEYDIKTKSLLNTSKELDKYNIYKITKNV
                     PYSLVESGVIHKDFSDDFINMYENVINGAKKASCVVKMKLPDENYIWNKVTLTTIFDE
                     DGNPVRAIGIQEDISKQKEAEIRYNQEGKYHSAILSEAMITYEINVSKDTFIKGNESW
                     QKPFGIKPDNNYSQMVKTIANSIVHKDNKETFLNTFLCENLLDAYKNNVTEIKLEYRR
                     MNQENKMIWVICTMHLIKDSITNDIKALAYVKDIDKKKNEEIRLKLKAERDTLTGLYN
                     KGTTEKLINDFLNSEEASLGMHAFLIVDIDNFKSVNDNLGHVFGDKVLFEVSKKLKPI
                     FRKDDIVGRIGGDEFIVFLKNIQSFENTKKKAEKICDIFRNSYTENKKTYKISGTVGI
                     SFVPEHGTVFEELYKKADIALYYAKSKGKDKYALYNDCIYQNELENNISENNIKLADK
                     CEKSKPVLKEILDSIDNYIYIVNPNTYELLFVNNKVSRLDLEIKLGETCYKSLLKSDR
                     PCNNCPLNGLKENKHSKFKIETNTFGKNISIASWINCIDGEYNCLIECIDSSLYKNK"
     gene            31060..31806
                     /locus_tag="KRH23_002388"
     CDS             31060..31806
                     /locus_tag="KRH23_002388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HHS5225666.1"
                     /translation="MLNSITLILGIIFTIYYFYLKIVFGGISFSEIFLVVGIVLIIYQ
                     IFKKKIKEKKVFYRVLKIIISIFLIVFVVTESLIIFYPKNSLESKSDYLLILGASVKK
                     TTPSTTLKGRLDTALKYLKINDNCYVVVSGGKGSGEKITEAKAMKDYLIKNGIDKNRI
                     IEEDKSTNTYENFKYSKLKIEEHSQRKLSDLKVKIVTTDFHVLRSKILAYRNGYKNTS
                     FYASKSKLSFVPTYYTREFFALWKTIIFDR"
     gene            complement(31755..32063)
                     /locus_tag="KRH23_002389"
     CDS             complement(31755..32063)
                     /locus_tag="KRH23_002389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HHS5225667.1"
                     /translation="MNFLKENSTFYFATVEDNKPRVRPFGFIMDYEGKLYFGIVKYKT
                     SYKQLLVNPNVEISTTSKVGKWIRIKGIEKTRYEFISSLFIYYLSKMIVFHNAKNSLV
                     "
     gene            32863..36636
                     /locus_tag="KRH23_002390"
     CDS             32863..36636
                     /locus_tag="KRH23_002390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdrD B-like domain-containing protein"
                     /protein_id="HHS5225668.1"
                     /translation="MATVSGQIVFDRNRSATIDSGDSGIANIPVVLQDIATGVRLVVL
                     TDASGNYVFTNVPNGNYRIVEAFGTTGGVPTPGNFATAIVGPVPIAEMPPISSVTNPP
                     IGSTNLDGTTPNTLLITVAGSDITNQNILNGPVIYTPIENILDSCVSVSNINLITDAD
                     NGTFGFFPPGTPSNTGPEIEPYPNVTPDFTYVVPDPTKFTPLDGEYTVQNIMTNAMSN
                     VIGAWWRIADHTTGNETGRMMVVNGFNPGAVFFKSTVQVTPNTNYLFSTWILNLFKVT
                     GYPPPQLGVRIFDQNNNILYQATLGAQIPVNTNAPEWKEVGTVINSQNNNQLTVEFFS
                     EGESAIGNDYAIDDVSLREIAVPTFTPIKTSNTETANVGDIITYTVTLDNTCDSPLTN
                     VFFRDLIPNGLEFIPGTVTVDGVSVPGVDPNTGFPLPDIGGGTGVEVTFDVVVESIPN
                     PNPTNNIANIDYSYTPVEGGIPNDFSVDSNPVPVEVISADIEVTKLSEPTIVNPGEEL
                     IYTIKVVNNGPFPSENVVLTDDVPASIINPEYSLDGGVTFQPWNGSLNIGTLEVGETR
                     VIIIRGIVNPSTVGIITNTAVVSSTTADPNLNNNTSTIETEVNLLADILVMKTAEPNS
                     AVPGTLLRYTIQVENLGPANAENVILNDDIPASIINPEYSLDGGASFQPWNGSLNIGT
                     LNSGISLTVLIQGTVSLNSSEYIVNTATVSSTTPDPDLSNNISTIITPVNPQAGISII
                     KVADEDVAVPGEEFVYTIEIFNEGPSNATNVVLTDDIPDVILNPEYSLDGGATFQPWT
                     GSLNIGTVAPGQLIRIIIKGLVSSTATGDITNTAEVSADVPEPVTDSSTVTTPIVASA
                     DIEVIKTSNMDTAVPGETFSYTITVTNLGPSAAQSIVLTDDIPDVILNPEYSLDGGVT
                     FQPWNGNLSIGTLDAGEIRSIIIRGTVSQTAVGTIINTATISSPTPDPNPDNNTSTDE
                     TDISSLADISVIKGNEPVAIPGGRFIYGIEIANAGPSFAENVTLTDNIPASILNPEYS
                     IDNGVTFQPWNGSLDIGTLDAGEIRNIIIRGTVSQTAIGTIINTATVSSTTPDPNLNN
                     NTSTSEIDISSSADISVIKLANKTEACVGEQIDFVIVVSNAGPENAQNVTLIDNVLDK
                     LKKAVFSLDRGVSFQPWTGSLNIGTLPAGTLRVILLRGIIKSTCLDRLTNIAEVTSTT
                     PDSNLNNNISRVQVEIKQCCCNDCCCNNCSNCCCNDCGCKDYCCNCCKNDFWC"
     gene            37093..37440
                     /locus_tag="KRH23_002391"
     CDS             37093..37440
                     /locus_tag="KRH23_002391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HHS5225669.1"
                     /translation="MHENKKNLLDGSLAQYNDTAVPKIPVFAGNDITSEVYYFKPNQV
                     LNAHRHPNGEQIFVFLKGEGKMKLGEHECDVKNGDTVFVPTGEWHEITNGSNEEMVAV
                     QITKINAGAEYRG"
     gene            complement(37590..38639)
                     /locus_tag="KRH23_002392"
     CDS             complement(37590..38639)
                     /locus_tag="KRH23_002392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HHS5225670.1"
                     /translation="MFKKIVAIASSIIVSTICLTGCDFNSNDKKGESSSSKNLDKVTI
                     AEVTHSVFYAPQYAAITKGFFEDEGIKIDLINTQGADKTMAALISGEANVGLMGPEAS
                     IYVYNQNKNDYAVNFAQLTKRDGSFLVARKKMPNFSYNDLKGTEILGGRKGGVPLMTF
                     EYVLKEKGLTIGENLKAGNVNVRTDVQFGVMAGAFAGGEGDFTTAFEPTATAMEKEGS
                     GYIVTSIGKDSGEIPFTAYSTTRSYMKNNKDLIQRFTNAVYKGQLWIQQASSKEVAKA
                     MQPFFEDISLEDLTTVVDRYKSIDAWSQNPVLKEEGLKKLMTVMKEAKELDKEAPYKD
                     IVNTEFANNAIKNIK"
BASE COUNT        15490 a         4329 c         6589 g        12373 t
ORIGIN      
        1 tatgttattt aaaattaaat ataaaacctt ctaaataatt gttttaaata attacatttg
       61 ttaacattat tataggcgat taataaattg tttaccacag cattatataa tatattaaat
      121 atgataaaat cattaaaaag tgtatcaaaa aacaattaaa gtgaggcgat agcagtggaa
      181 aaagcttgta agtttagaat atatccaaat aaaaaacaac aagagttaat taacaaaact
      241 tttggatgtt gtagatttgt atataataag tatcttgcta aaagaataga agtttataaa
      301 aacgatagag aaacttttac ttataaacag tgtagttctg atttgaccaa tttaaaaaaa
      361 gaattaaagt ggcttaaaga acctgacaaa ttttcactac aaaacgcctt aaaagattta
      421 gataatgcat ataaaaaatt ctttaaagaa aaagcaggat ttcctaaatt taaatcaaag
      481 aaaattaata gattttcata taaaactaac tttacaaatg gaaacattat gtattgtggt
      541 caacatataa aactacctaa acttggtatg gttaagataa gggataaaca agtacctcaa
      601 ggtagaatac ttaatgctac tatatctaaa gagccaagtg gtagatatta tgtatcatta
      661 tgctgtactg atgtagatat tgaagtattt gaaaatacta acaatcagat aggtttagat
      721 ttaggaatta aagaattttg tatctcaagt tgtggagagt ttatagaaaa tcctaagtat
      781 cttaagaagt cattaaacaa gcttgctaaa ttacaaagag aattatcgag aaaaacaatc
      841 ggtagtttaa atagaaataa agcaagatta aaagttgcaa gatttcaaga acatatagct
      901 aatcaaagaa atgattttct gcaaaaatta tctactaaat taataaaaga gaatgatatt
      961 atttgcatag aagatttaca agtaaagaat atgattagaa atcgtaaact atctcgctta
     1021 atttcagatg tatcatggtc agaatttatt cgtcaattag aatacaaggc taattggtat
     1081 ggtagaaaaa ttgtaaaggt aggtaaattc tttgcaagtt cacaaatatg caataaatgt
     1141 gggtataaaa atgaggaagt gaaggactta aatataagag aatggatttg tcctagttgt
     1201 aatgaaactc acgatagaga tataaatgca agtataaata tattaaaaga aggattaaga
     1261 ctaataacaa ttcaaaataa ataacttatg taagaaccgt aggaactacg gggatagcct
     1321 gtggagaatt agtaagacat attttagtat gcaaaattct gtgaagcagg aaccctgtga
     1381 ctttagtcat gggaggttca gtgtagcaat aaatatatat cacctggctt tattgatgca
     1441 catatgcata ttgaatctac aatggtaatg ccaattgaat tatcgaaaaa attattaaaa
     1501 tcaggtacga caactatcat agccgaccca catgagttgg tcaatgtaaa aggagctagt
     1561 gcaatagatt ttttattaga atcgacaaaa gatataccac ttaatgtata tattatggtg
     1621 ccttcatccg tacctgcaac aagttttgaa actaatggag ttggtaaatt tagtgcaaaa
     1681 gacatggaga gttatgtaaa taatcctaga attttaggtt taggagaggt aatgtgtttt
     1741 aatgatgtta taaattctga aaatgaaatc ttggataaac tagagctttt taaaaataaa
     1801 gttgtagatg gacatgcacc taatataaat ggtaaatcac ttcagacata tgtatgtgca
     1861 ggaatagaaa atgaccatga atgtataact tttgatgaag tatatgaaaa attgagagca
     1921 ggattaaaaa ttttaataag agaaggaagc gcagcaaaaa atttaaagtc tatagtaagt
     1981 ggtatgctaa agcataactt gccaattgaa gaatttatgt tttgcacaga tgataagcac
     2041 ttagatgata tagaaaaaca aggtcacata agatggaata taaaatgtgc gattgattta
     2101 ggtatggaac ctgttagggc tataaaagtt gcaacttata attctgcaaa agcatatggg
     2161 ttaaggaaaa ttggagcaat aggtgcgggt tataaggcag atattgttgt attgaatgat
     2221 ttagacaaaa tggaagtgga tagtgtatat aaagatggta atttggtaaa cgaagagatg
     2281 ttttctaatt acaattatga gattaaagat aaagaattgc ttaatacagt caagtttaaa
     2341 tatattaata aagaaaaaat acagttaaaa gtaagtgaaa aaaattatgt aatggagatt
     2401 gtaccttatc aaattttgac aaataaggta tatgaatctt taccatgtgc agatggatat
     2461 tttgttccaa ataaagagta ttcaaaactt tgtgttgttg agagacatag aatgactgga
     2521 aatgtagcag ttgctccact aaaaggattt ggcataaaaa atggagcaat tgctactact
     2581 gtggcccatg attctcataa tattatagtt gcaggggata atgatgatga tattctagta
     2641 gctataaatt acttaaagga aatacaaggt ggttatgtaa ttgtatcaaa tggaaaagtt
     2701 cttgcacacc taagtcttca agtagctgga ttaattagta cttttacagc tgaagaagta
     2761 caagaaatta ctgataatat gttggagata gcaagaaaaa tgggagttcc agagtatgta
     2821 gaccctttta ttacactttc ttttatggca cttccagttg ttccacaaat aagacttaca
     2881 gatttaggtc tatttgatgt tgaggaattt aaatttatat agataatata aaagtaataa
     2941 taaatgaggc tttctcaaaa tagggataag tctcttttta ttgttgaaat gatgaaaata
     3001 tatttgattt catacaaaaa agagcatctc atgaactaaa aattttattt ttagatatcc
     3061 ttattttaat taatctatca tttaaccttg ttttaagcat agatatctta ataaaactat
     3121 tttcagtcta ttttaacata taaatacatg aaaattatat atttatgaaa ctttatacat
     3181 aaaaaataaa atattttatt tatatataga tttatagggt aataatataa gcatagtata
     3241 aaattattaa taaaaacaaa aggagagata tttatgttga gtataggaac aaaagcacca
     3301 gaatttacac tagaagataa agatggaaat aaggtaagta tgtcagattt taaaggtaaa
     3361 aaagtagtag tatattttta tcctaaagat aatacaccag gatgtacacg tcaagcttgt
     3421 gcttttagaa atgcatatga tggttttaaa aaggaagata tacaagttat tgggataagt
     3481 aaagatagta taaaatcaca tcaaaaattt gcagaaaagc atgaacttcc ttttatttta
     3541 ctttctgacc ctgacttagt tgctataaaa gcttttgatg tatggaaaga gaaaaaaatg
     3601 tatggaaaaa ctgcattggg agttgtacgt gcgacatata ttatagatga aaatggaatt
     3661 attgaaaaag tctttgaaaa agcaaaacca gacacaaatg cacaagagat tcttgaatat
     3721 ttggaaaaac aggagtaata agaatttatg attataatgt tatcaccagc taaaaatatg
     3781 aagaatatag aagtatttga tagagatttg agtttgcctt gttttataga taacacaaaa
     3841 gaaatagtgg aaaatataaa gacatttggt atagaagatt ttaaaaataa aatgaaaatt
     3901 aatgaaaaat tagctgtatt aaataaaaat agatttgaaa gcattaaatt tgatagatta
     3961 ggaaaccctg caatcttaac ttatgatgga atacaatata aaaatataga agcagaaaat
     4021 tttacaagga aagatgaaga gtttgcaaat agctgtattc gaatcataag tggattgtat
     4081 ggtgttgtaa aaccatatga tagtatatat gaatatagat tagaaatgca gacaaaatta
     4141 cgagtaggtg agtttaagaa tttatacgaa tattggggaa atcgtatata taaagaacta
     4201 atcaaagaaa aaacagctat cgttaatctt tcatcaaatg aatacagcaa atccatagaa
     4261 aaatttatta aagatagtga tacatatatt acatgtactt ttaaagtaaa taaaaatggc
     4321 atattgaaag tggaatctac acaagcaaag aaagctagag gtatgatgac aaaatacatt
     4381 gtaaaaaata ggataagaga tattgaagaa ctgaaaaagt ttaatttaga aggttataag
     4441 tataaagaaa acttatctaa caatagtgaa tacatatttg taaaagagta gaagttttgt
     4501 taaatattaa atggcattgt taaatttagg taaaatatac ttagtgtgta ttgaattgaa
     4561 cttgatttta aaatataatt attcttaaat taaaaaaaga aaggagtggt cttccaaaat
     4621 ggaaaatcac aaacagatgc cttggcattc aagagcaacg catgaaattt tagaaagtct
     4681 agattcatca gaggaggggc tcaccgatac cgaggcggaa aaacggctta aagagaatgg
     4741 tttaaatgaa cttagaaaaa aaccacctag aacaacttta caaatgcttt ggagtcaaat
     4801 tacagatgct atggttatga tactaatagg agcagcaata ttatctttga tatttggcga
     4861 atttacagaa gcttttgtaa tactaataat tgtaacagta aatgcagtta ttggaattgt
     4921 tcaagagaaa aaagcagaat catcattaga agcattaaaa aatatgaatt cacctacagc
     4981 tcgtgttatg cgtgatggtg aagaaaatgt tattccagca agtaatcttg tagtaggaga
     5041 tattgttttt ttagaagatg gagctatggt tccagcagac cttcgtttaa tagaaacatc
     5101 aagtttaaaa attcaagagg cttctttaac aggagaatct gttccatcag aaaaagatgc
     5161 agatacaatc ttacctaaag aatgtgtatt aggagaccgt agcaatatgg cgtatacatc
     5221 ttcaatagtc acatatggta gaggtgtagg tgttgtagta gcaactggta tggatacaga
     5281 agtgggtaac atagcacatc ttttagattc acaagatgat tttgatactc ctataaaacg
     5341 taaacttaat actgttggaa agacattaag tgtcataggt attattgtat gcgttgttat
     5401 atttgcaata ggtgcatttt atcagagacc tctcttgcca atgtttatga ttgcaatttc
     5461 ccttgccata tcaattattc cagagggatt acctgcaaca gctactattg taatggcttt
     5521 aggcgtacag cgtatggcta aaagaaatgc tttaattaga aaattacctg ctgttgaaac
     5581 attaggagga gctacagtaa tatgttgtga taaaactggt acgttaacct taaataaaat
     5641 gactgttaca catattgctg tcaatggaga ttttgaatct ggaaaagtga catcaataga
     5701 tactgcatct gaaaaacatc cattagtgta taaagagatt gtttatgctg gtgcactttg
     5761 taatgatgca tgtattaatc cagataaaac agatgaaata ttaggtgacc caacagaggg
     5821 cgcattaatt tttatggcca aaaaatttgg aatagatcaa gaagctcttg aagaagaata
     5881 tccacgtgta tttgaacagc cttttgattc agatagaaaa tgtatgacaa ctgttcataa
     5941 tatagatgaa aagattattg cttatactaa aggagcagta gacgaaattc ttgacctatg
     6001 tactaaaata ttaacttcaa aaggtgaaag aaacattacc gaagtggata aaaagaatat
     6061 acacgaatta tgtcttaaca tgtctaaaaa tgcattgcgt gtacttggtt ttgctaagcg
     6121 tgagatttca tctataccaa aagaagatag tgaaaatata gaatatgatt taacatttat
     6181 aggtatggtt ggtatgattg acccaccaag aactgaggta attgatgcag taagtacttg
     6241 taaagaagca ggtataagaa ccataatgat aacaggtgac cataaagtta ctgccacaac
     6301 aatcgctcat gagttaggaa tatggagtga agaaaatact gtgatatctg gtgatgaact
     6361 tgataatttg agtgatgatg aactagatga agctgttaaa aatactacag tatttgctcg
     6421 tgtatcccca tttgataaac ttagaattat acaatctcta aaaagaattg gagaagtacc
     6481 agcaatgact ggggatggtg taaatgactc tcctgcctta aagtctgctg atattggtat
     6541 agccatgggt ataagtggta cagatgttgc aaaagattct tctgacatga ttttaatgga
     6601 cgatagtttt acaacaattg cttatgcaat aaaagaaggt agacgtgtat atagaaacat
     6661 acaaaaagtt atacaatttt tgcttgttgg taatatagca gagatactta cgttgtttgt
     6721 agcaatatta ttaaattggg atactccgct tcttgctgtt catattctat gggtaaacct
     6781 tgcaactgct acgcttccag cccttgctct tggagttgac ccaccaagca gaaatataat
     6841 gaaacaccag ccagtgaaat caaccacttt gtttgaaaaa aatcttatac aaagagttgt
     6901 tacccaaggt atatttgtgg caataatgac tattttagca tataaaattg gtcttaatat
     6961 agaaaatcat tctgtaggtc aaacaatggc attttgtgta ttagcatttt cacagatgtt
     7021 acgagcattt agtcagcgtt caaatacaga ttcaatgttt aatagaaata atggtaaaaa
     7081 tccatttctt ttaatctcat ttttaacttc tgcattttta atagcagtaa tactgtttgt
     7141 acctgttttt agaaatgctt ttaacttaac agttttaaat aacttagagt ggcttataac
     7201 gattgtttta gccataatgt ctgtaattca agtagaggtt gggaaaatta ttaaaagaaa
     7261 aaaattaaaa aaatagttga caaaattagg aaaaatatat aagatataaa acatagaaaa
     7321 attaaataaa tcttatccag agaggtggag ggactggccc tatgaaaccc ggcaaccagt
     7381 atatttatat acattggtgc taaatcctgc ggcgaaagct gagagatgag tataattaag
     7441 cttatacaga gcctgagtta tatactcagg ctttatttat tttaactctc atctggtaaa
     7501 tagtttaatt ttttttacta aaatctaagg gggatacaag aatgtataat aaagaaacaa
     7561 tatgtgtgca aggaaattat aaaccaggta atggagaacc aagagtacta cctttatatc
     7621 aaagtacaac ttttaaatat agcagtatag accaacttgc tgaattattt gatttaaaag
     7681 ttgatggaca tatatattca agaataagca atcctactat tcaagctttt gaagaaaaaa
     7741 taagtttact agagggtgga gtatcttctg tagctgtatc atcagggcaa tctgcaaata
     7801 tgttggcagt tttaaatata tgtaaatcag gagatagtat actttgttct tcaaaagtat
     7861 atggaggaac attcaattta ctaggaccta gtcttaaaaa atttggtata gatttaatat
     7921 cgtttgactt agattcaagt gaagatgaga tagtagaact tgcaaaggaa aatactaagg
     7981 ttgtgtttgc agaaacactt gcaaatccaa ctcttgaagt catagatttt gaaaaaatag
     8041 caaatgtagc taagagaatt aatgttccat ttattgttga taattcatta gcatctccag
     8101 tgctttgtaa ccctttaaag tatggagcaa atatagttac tcattctacc acaaaatatt
     8161 tagatgggca tgcttcaagt gttggaggaa ttatagtgga tggtggaaac tttaactggg
     8221 ataatggaaa atttccagaa ttagttgagc cagacccaac atatcatggt ataagctata
     8281 ctcaaaaatt tggaaatgcc gcatatgcaa ctaaagcaag agttcagttg cttagagact
     8341 atggaaattg tttaagccca ttcaatgcgt atcttactaa tttaaatgtt gaaacactac
     8401 atcttagaat ggagagacat agtgaaaatg cacttaaaat agctagattt ttagaaaaac
     8461 atgaaaatgt agattggatt aattacccag gacttgaaga taacaagtat tatgagaatg
     8521 ccaaaaagta tttatcaaga ggatgtagtg gtgttttatc atttggagta agaggtgggt
     8581 tagaaaatgc caaaaaattt gtggaaaaat tacagatagc atctttggtt acacatgttt
     8641 cagatgtaag aacttgtgtt atacatccag cttcaactac tcatagacaa ttaacagaag
     8701 aacaattaat tgcatctgga gtattgcctt cactaataag attatctgtt ggaatagaaa
     8761 atgtagagga tttaatagct gatttaaatc aagctttaaa tttctaatat tctaagagaa
     8821 agagaagtga aaagatatgg ctttaatact accaaaggga ttacctgtta ttaataaatt
     8881 attagatgaa ggaatagatg taatttataa agaagatttt aaaaaggaat taaagtatga
     8941 agaaaacata gacactaaga tagctatact aaatctaatg cctataaaga tagatacaga
     9001 attagattta ctaagaagga tagataaaac aggattcaac gtgtctgtgg aatttattaa
     9061 aatttcaaca agagaaagta aaagaagttg taatgaatat gttaaagaat tttataaaac
     9121 atttgatgaa gccaaaggag agtattttga tggctttata ataacaggag ctccagttga
     9181 acaaatggag tttgaagaag ttgattattg gaatgaacta gaagaaatta tggattattc
     9241 taagagaaaa actaaatcta cattatatat atgttgggca gctcaagcaa gtctttacaa
     9301 atactacaat gtaaaaaaac ttccactaag tcaaaaatgt tttggagtat ttaaacataa
     9361 ggtagataaa gatagtaaaa tagtagatgg atttgaaaat gaattttttg ctccacattc
     9421 aagacatact actgtaaata ttgaagcttt gaaagagaat aaagagttga gcattgtgag
     9481 tcattctaaa gaagctggtc cctatataat tacaaattca agagatgtgt tcgtaatggg
     9541 tcatagcgag tatgacaaat acactcttga taaagaatat aagagggata taaataaagg
     9601 agataaaata tctatacctc aaaattacta tattaatgat gacccttcag aagagccaac
     9661 tgtaaaatgg aaaaaacatt cagaattgtt gtttagaaat tggataaaaa actatttgat
     9721 acaataaatt ttaagagtat ataaatgtta actaaaaaaa tatagaaatt tataggtata
     9781 aagttaatct taatgatact ttatacctta tttttttaaa atttgacctt ataatagtag
     9841 ttttatattt taagaaaatc actttaggtg tatgtagata gaggtggttt taattttata
     9901 tatggtgcga taatgggaga ctaaaccttt atagtatcaa taaatttgta ttttaacttt
     9961 taaaagagat taaaaaggga gaaatcagtg taaaatatat atagattttt tattaaattt
    10021 tattaaaaat atcctgtata aaattaaata tcaataagat aacaaaattt caattgaagt
    10081 tacaatattg taattgacaa taaatactta atactataat atttaataca ttaaacatta
    10141 tagtgttaag tatttattta cagtatgcac ttcagcctaa atttgaaata aagtattttc
    10201 gtagggagcg tttgtatgga tgagatgagt tttaagaaag agctactaga gttgactaga
    10261 gatataaata tgaaatttac aactttatta agtgattttt atcagccact tggtattaca
    10321 gcagtgcaag ctttgatttt atctgagtta tgtgaacatg gagagaaaaa aataagcgat
    10381 ttagggaaga acttaaacat gacaaatagt aatgtatcag taatctgtca aaggcttgaa
    10441 aaaaatggct ttttaaatcg cataagagat atagaagacc aacgaattgt aaaagtaaaa
    10501 gttacaaata aatcattgga tatacaagaa catatttcaa gtagtatttt tgatagttat
    10561 tttgaaaata tgaccagtga aaaattgcaa gatatggaag atataataga aggtttagag
    10621 aaattaaata aacttttaac ttacattgat tgcaaataac ataaaaataa tttaaaggag
    10681 aataaaatta tggatgaaca taaaccccaa aaaaggtcag cactctatta ttatacagtt
    10741 ataataatag tagtaatgtt tttaaatgct ttaatatttc caagtttaat ggataaaaaa
    10801 atggttgaga ttgactatgg aaagtttctc acaatgttgg atacaggaaa ggttaaatct
    10861 gttgagatag aaaataatag aatagcaata aatccatcta gtagcaagga taagaatata
    10921 tacataactg gtagaatgga tgacccagaa ttggtagata gactaaaaaa tgcaaaagta
    10981 gaatttacta aggttattcc taaggaaaat tcacctcttt taagtatttt acttacatgg
    11041 ataataccta taggtattct tatgctattt ggtaacttaa tgatgaagtc tatgcaaaag
    11101 cgaatgggtg gtaatgctat gcaatttgga aaaagcaacg ccaaaatgta tgtatctgct
    11161 caaagtggaa aaagatttaa tgatgtagct ggtcaagatg aggcaaaaga agctttaact
    11221 gaaatagtag atttcttaca caatccagaa aagtataaaa agataggagc acaaatgcct
    11281 aaaggagcac ttttagtagg acctccaggt acaggaaaaa cactccttgc aaaagctgta
    11341 gcaggtgaag caaatgtacc atttttctca atatctggtt ctgagtttgt tgagatgttt
    11401 gtaggaatgg gagcttctag gattcgtgat ttatttaaac aagcaaaaga aaaagctcca
    11461 tgtatagtgt ttatagatga gattgatact attggtaaaa agcgtgataa tggaagtgga
    11521 ttaggtggaa atgatgaacg tgaacaaact ttaaatcagt tgttaagtga gatggatggt
    11581 tttgatggtg gaattggagt agtaatactt gctgctacaa atagacctga cagtcttgac
    11641 aaagcattac ttcgtccagg aagatttgat agacgtatac cagttgaact tccagacctt
    11701 ggaggacgtg aagctatatt aaaggtacat gctcaaaatg taaatgtaag ctcagatata
    11761 gattataatg caattgcaag gtctacatca ggagcatcag gtgcagaact tgcaaatatt
    11821 gtaaacgaag cagcactttt agcagttaag tctggcagag atatagtaga acaacaggat
    11881 tttgatgaat ctgttgaaac tgtaattgct gggtatcaac gtaaaggagc tgtaatttca
    11941 gataaggaaa agaaaattat agcatatcat gaaataggtc atgcacttgt tgctgctatg
    12001 caaaaacatt ctgcacctgt ccataagatt actataatac ctagaacttc aggagcattg
    12061 ggatatacta tgcaagttgc tgaagatgag agtgtactta tgtctaaaga agaagcaatt
    12121 gataaaataa ctacttttac aggtggtcgt gctgctgaag aggttatctt taacacttgt
    12181 acatcaggag catcaaatga tatagaacaa gctactaaaa ttgcaagagc tatggttact
    12241 cgccttggta tgagtgaaga gtttgatatg gtcgctcttg aaactgtaag caatcaatat
    12301 ttaggaggag atacttctct tgcttgttct tccgacactg ctgctaaaat agatgaagag
    12361 gtatttaaaa tagtaaaggc ttgtcacaaa aatgcaattg aaatcttaga aaataatatt
    12421 gataaattgc atgaacttgc taattattta ttagaaaaag aaactattac aggtgatgag
    12481 tttatggaaa tacttaactt aaactaaaat gattatacac aagataaaaa tgcctattgt
    12541 taggcatttt tattttacaa ctaaattttt taaattcata tttaaatctt tacataatct
    12601 taatcattaa aaatacatct taactacaat tttatatcgg aattgatatt ataatagtaa
    12661 tgaatggtgt aaggaggttt tttaatggat agacctaatc ctgatattct attagaaaaa
    12721 attaaaaatg aagaagaaaa actaagtaga ggtcaattaa aaatattctt tggttatgca
    12781 gctggagtag gaaaaaccta ctctatgttg gaatctgcac aaaatttaaa aaaagtgggt
    12841 gtagatgtag tagttggata tattgaacca cacactagac cagaaacatt ggctttactt
    12901 gatggcttgg aaattcttcc tgtaaaggag atagaatata aatctataaa actaaaagaa
    12961 tttgatttag atgctgcttt agaaagaaaa ccagaagtta tattagtaga tgaatttgcc
    13021 cattctaatg ttgctgggtt aaggcataca aaaagatggc aagatataga agaattgctg
    13081 ttagcaggca taaatgtcta cactactgta aatgtacaac atttagaaag tctaaatgac
    13141 attgttgaga taattacaaa cgtatcagtt aaagagacta taccagataa gtttttggat
    13201 acaaatacac agttagaact tatagatgtt gaacctgatg tacttcttga aaggttcaat
    13261 gaaggtaaga tatataagaa agaacaagct actagagcaa aaaataattt ttttataaaa
    13321 gataacctgg ttgcacttag agaaattgca cttagaaaaa cagcagagag agttaataaa
    13381 gaagttcaaa tgaccagact atcaaagggt gatgtaactg taatacctac atcagataca
    13441 cttcttgcat gtataagtcc atctccatct tcagcaaaag ttattagaac tgcatccaga
    13501 atatcagaca gtacatttgc aaaatggata gctttatatg ttgaaactcc aaacacagca
    13561 agacttccat ttgatgaaca aaaacaacta caaaataacc taaaattagc taagaaatta
    13621 ggtggagaaa taattgtttt acatggtgaa aatataatag agcaaatact tagaattgca
    13681 aaactgagaa atgtaacaaa aattgtaata ggtagaaatc attcaagtaa taaaagattt
    13741 agtaaaaaat ttaaaaaaga tatagttgac aaattaattg atgaagttga ttatatagat
    13801 atacatataa ttccatataa atttgcctca gatgttaaat acaaacctaa aaaggataaa
    13861 tcatcaataa aatctaaatt taaaattagc aaagttgatt ttataaaact tatatttatt
    13921 actttgatga taagtatttt agcatatgca gtacaaagca tgggatttat aagagaaaat
    13981 atattgttaa tatatatgtt gggtgtagtt ttagtttcta tgtggactaa agggtatagt
    14041 acaggtataa taagttctgt atttaatata gttcttttaa attatttttt tacagcacca
    14101 ttatatacat tatctatagc agattcaaac tatatagtaa cactggttgt attctcaata
    14161 gtaggtataa taactagcac tcttacgtct aagatacagc atgaagcaga aactgctgct
    14221 aaaagagaag aaaatacaaa aatgatatat caaataatta agggattttt aagattatca
    14281 aataaagatg atatagtaaa caaaggtata gaacttttgt ctcttagctt aagtagagat
    14341 gtaatttgtt atttaaatgt agataagcat aataaatcaa agctttacaa aaaaaatact
    14401 aataataagg ataaaaatga tttggatagt gaagatgaaa aagctgttgc aagttgggtt
    14461 ttatccaatt caacagtggc aggaaatgac acggatacac ttcctggttc aaagggatac
    14521 tatataccaa ttgtaggaat gaatttaact ttaggagtag tgggaatatc atgtattgat
    14581 tcgaaattgg atacagaaga tataagctta attgaaacaa taattgctca aatggcaata
    14641 gcgcttgata gagaaatctt gtcagaagct aaagaaaata ccaatcttga gattgaaagg
    14701 gaaagattaa gaagtaatct tttaagagca gtttcgcatg accttagaac tccactagca
    14761 ggaatatctg gtgcagtaag tacaattata aaaaacaagg gtactatagg tcaagatata
    14821 atagatgaat tacttagtgg tgtatatgaa gatactcagt ggttaataag acttgttgaa
    14881 aatttactta gtatgaccaa gatagatgaa gggaaattgg aagttaaaaa acattctgaa
    14941 ctggttgagg aaattatatc agaagcgtta caaaaaataa aaaaaagaat tgaaaatgca
    15001 cttatagata ttaatatacc agaacagata ttatttgttc ctatggatgc aaaattaata
    15061 gaacaagttt taattaattt aatagataat tctttgaaat attcaaagga agattgtaag
    15121 atagagataa atgtatatga gaaagatgat tatgtttggt ttgaagtatc tgataatggt
    15181 cctggtatat caaaggaact taaaaagcat atctttgaca gattttttac tggagaagaa
    15241 ggagctaaag attccagaaa gggtgttgga cttggattat caatttgtaa atctataatt
    15301 caagctcata aaggtgaaat tatggtagaa aacaataaag ataagggttc aacttttaag
    15361 tttagtttgc ctaaggaaaa tgaatagttt taaattttaa aattagtttt ggaggaagaa
    15421 atgagtaaaa aacttatatt gttagtagag gatgataaga caataagaaa atttatatct
    15481 actgcacttt taacacagga ttatgatgtc aaggaggcta taactggaaa agaaggtata
    15541 tctattgctg tctcatattc tccagatgtt gttcttttag atttaggctt agaagatatg
    15601 gatggaatag aggtaataaa agctatcaga caattttcaa atataccaat aattgtagtt
    15661 tcagctagag agcaagatag agacaaggta gaagtatttg atgcaggggc agatgattac
    15721 ttaacaaaac cattctccat agtagagtta ttagcaagag taagagtagc atttagacat
    15781 tcacaagtag aagctcaaca aaaagatgat gttaaatcta cgtttgaagt agataaatta
    15841 ttgattgatt ttgataaaag aaaagttatt gttgatgatg ttgaagtcca tttgacacct
    15901 attgaatata atattctttc attacttgca aagcatcatg gaaaagtgct tactcataat
    15961 tttataataa aagaaatatg gggtagtgtt atagggaatg agactaagtc tttaagggtc
    16021 tttatggcaa cgttaagacg aaaaatagaa aaacaacctg caaacccaag atatataatt
    16081 acagaagttg gtgtaggata cagattaaat gatgaatagt tgtaatatat taattattag
    16141 attatgtgct tattaatata tattaaaatt atatagttta gttaaaataa gaatgaagtg
    16201 tatgtgcttg ttgtcagttt agcacataca ttttattttt tagctttttt agtatcaata
    16261 attttttagt atcaataata tgaaatatgt tttaaaataa gtatatagtg taatctgtaa
    16321 taaaaacttt ggttaaataa taaatgtatt taacacttac cttataataa atttaatata
    16381 aatattaaat aataattatt aaaatagtgt aaaataatta cagtaaggat tataaaaaat
    16441 ttttagaatg taaattgaaa tttaggagta gatgtatgta tatactgaat ttaaatacaa
    16501 gagagactat tgaagatttt agagataaat tttatgtagc agaaaattct tatcttatat
    16561 taagtgctcc aaaaaattta aaattgctta aggaaacttt ggatatagat gaaataactt
    16621 ttaatgattg tcttaaattt gatgaaataa ccaaacttga tttatttgat aattacgatt
    16681 ttttaagcct aaatacattt gaactaagag atggagaagc tgttatagaa gaggtaaata
    16741 tgtatttatc agataatttt atattggttg tagtgaatga agaacacttt ttatttgaat
    16801 ttgtaaaaaa tattattttg aagaactctc aacttgaaaa aaatccagtt attaatctat
    16861 ttaagataaa ctacttgatt cttagagaag ttataaaaaa tggttttgag tctttggaaa
    16921 aagttgaaga gttaattctt caaatagaag atgaaatgat ggacaacatt aataagaatc
    16981 atgtatctag aataagtgat gtaagaggat taacaagaat tatagttaag aatactagac
    17041 ctcttttgta tattggggat agaatagtta aggaaaatat aaggtattta aaatattcaa
    17101 atgtaaaaaa atataattta gaaaattttc aaggtataga ttttggaatt gacaaattat
    17161 acaatttcgc attgtcaaca cgagagttag cagataaatt attagatatt tattcttcca
    17221 gagtaggtga gaaaacaaat aacttaatta caaaattaac cttgttaaca gccatatcag
    17281 caccacttac aattataact ggtatatatg gaatgaactt tagatatatg ccagaattaa
    17341 actggattta tggatatcca gcaactttat tttttatgct atgtataatt tttgttggaa
    17401 ttataatatt taaaataaaa aaattattgt aaattacaga tgatgtttaa ttgattttat
    17461 aaaaatacat caattgagaa gctgatttaa gtgaataaaa aaatatttta aattgaaaat
    17521 atttatagaa aatattgaca attatatttt ctttgttata attattaaac aagaagaata
    17581 ataaattata aaaatggagg ataatactat gaaaggaata ttaaaagaac taacagcaaa
    17641 actttatagc tttttttact ttatgttctg gggcttttat tttagcgctg gctatttctt
    17701 ttacaaaaat atatgtactt cctttctggt gaggccttat tttagtgatt ttgagcataa
    17761 gtaaatttta taaaaatgat tattttatat atttatataa gatttagtgc ttgatagatt
    17821 attttagaga actcattagt gagttctctt ttttatttta aatataaaat tataatattg
    17881 ggaggtagta aaaatgatag tagtattaaa aatgggagca gataaaaatg aagttaaaaa
    17941 attaattgag gctattggga gagaaggagt agaagttaat cccatagatg gaacagaatt
    18001 aactgtttta ggtttagttg gagatactag taaaatagat gccaaaagaa tagaagcaaa
    18061 taaggtagtt gaaaaagtta tgcatgtggt agagcctttt aaaaaggcca atagaaaatt
    18121 tcatccagaa ccttcaatca taaatgttaa tggaatggaa attggttcaa agaaaattgc
    18181 tatgatagct ggaccttgtt ctgttgaaac agaagaccaa atagtatcta tagctaaaga
    18241 tgtgaaaaaa tcaggtgcag gatttttgag aggtggagca ttcaaaccaa gaacatcacc
    18301 atacgctttc caaggattga aatatgatgg attggattta ttaaaaaaag caaaagaaaa
    18361 aacagggctt cctatagtta cagaaataat gtcaacacaa gatatagata tatttgaaga
    18421 aaatgtagat gtaattcaag ttggagctag aaacatgcaa aactttgatt tattaaaaga
    18481 attaggtaaa acaaataaaa caatactttt aaaaagagga ttatctgcta caattgaaga
    18541 gtggctaatg tcagcagagt atataatggc tggaggaaat gaaaatgtag ttctttgtga
    18601 aagaggtata agaacttttg aaacatatac tagaaatact ttggatttaa gtgcaatttt
    18661 agctgtgaag aaacttagtc atttaccagt tatagttgac ccaagtcatg cagcaggtaa
    18721 atcatggatg gttgactctt tatctaaggc agcaattgca gttggagcag atggtctaat
    18781 aatcgaagtt cataatgacc cagcacatgc actttgtgat ggaaaacaat cgattaagcc
    18841 aaatgaatat gatgaattga taagtgaatt aaagactatc gcatcagcag ttggtagaga
    18901 aatataatct ataaaaggat ggttaaacgt ggaagaaaaa ctattagtaa atttaaaaga
    18961 aaatagctac aatatattta ttaaaaaaaa tatactaaag aatataggag aagaaataaa
    19021 aaaaatatat tttggaaata agatttttat tgtaactgat gaaaatatag caaaattata
    19081 cttggataaa gtaaaaaata atttaagtga atctggattt gaaattaaat ctttaatatt
    19141 aaaatctggt gaagaaacaa aatcatttaa tactcttcct aaaatatacg atagtttact
    19201 tgactttaag ttaactagaa aagatttgat tattacttta ggaggagggg taataggtga
    19261 tttaggtgga tttgcagcag caactttttt aagaggtata agttttattc aaattccaac
    19321 atctttatta gcacaagttg atagttctgt aggtggaaaa gttggagttg accttgagag
    19381 aggcaaaaat ttagtgggaa gcttttacca accaaaggct gtgtttatcg atccaaatgt
    19441 attattatca cttccagaaa aattctatag agatggaatg gcagaagtta taaaatatgg
    19501 atgtataaaa gacaaaactt ttttcaataa acttttaagt ttaaaaaata gagaagaagt
    19561 aatgcaacat atagaataca ttatacataa atgttgcttt attaaaaaaa ctgtagttga
    19621 agctgatgaa aaagactttg gagatagaat gcttctaaac tttggccata cattaggtca
    19681 tgctattgag aaatactaca attttacggg ttatacccat ggagaagctg ttgccatagg
    19741 aatgtataag ataactttag aaagtgaaaa gataggaatt acaaaaaaag ggacatcaga
    19801 acttataaaa tcaattttaa tgaattataa tttgccttat gagattgaat taagagataa
    19861 taaatctata gtagatgcta tatctcttga taaaaaaaat ctaggtgata cattaaaaat
    19921 aatactttta aaagatattg gagagagtat tatatataat actacttcta aattttttca
    19981 ggaggtaaga taatgggaag tctaaaaata tatccaagta aattatctgg agatgtaaaa
    20041 ataccaccat caaaaagtat ggcacatagg gcagttattt gttcatctct aagcaatgga
    20101 aaaagtagaa tttctaatat agatttttct gatgatataa tagctactat aagagcaatg
    20161 acatcattag gagctattat agaaaagaaa gaagatattt tagaaatttc gggaattttt
    20221 tctaaagaag gtattttaaa tagagagaat cagttgaatc aacctaaatt gacaatagat
    20281 tgtaatgaat caggctctac attgagattt ttagtaccta tatctttagc atttgatggt
    20341 gtaaaaaggt ttataggtag aggaaatctt ggaaaaagac cacttgatac ttattatgag
    20401 atatttgaca gacagaatat aaaatatagt tacaaagaaa atcagttaga tttgattata
    20461 tcaggtaagc ttaaaccaga tgaatttaga gtaaaaggaa atataagttc tcagtttatc
    20521 acaggtctac tgtttatatt gcctacgcta gagagtgatt caaagataat aattaccact
    20581 gagctagaat ctaaaggata tttagattta actctttcaa cgataaaaga ttttggggta
    20641 gaaattataa acaataacta taaagaattt attataaaag gaaatcaaac gtataaagcg
    20701 agaaattata aagtagaagg agattattct caaggagcat tttatttatc agcagatgct
    20761 ataggagaag atattagcat attagacctt aaagaagatt ctcttcaagg ggatagtgaa
    20821 gtagttgaaa ttttatctag gatgggaatg gaaatattaa gagaaggcaa caaaataaaa
    20881 ggaataacaa atggtttaaa tggtactttg atagatgcat ctcaatgccc agatataata
    20941 cctgtattat ctgtagtagc atccttaagt atagggagga ctacaataat taatgctggt
    21001 aggcttagaa ttaaagaatg tgatagactt catgcaataa atgttgagtt aagtaaactt
    21061 ggagcaaata tagaggagaa agaggatagt ttgataatcg aaggagtaag caagttaaat
    21121 ggtggagtag aggtgtggag tcacaaagac catagaattg ctatgacact tgcaattgct
    21181 tcttgtagat gtgataaacc aataatatta aaagattttg agtgtgtatc aaaatcttat
    21241 ccacattttt ttaaagattt taagatgtta ggaggtcgaa ttgatgagtg gaatatgggg
    21301 aaataattta aaaatatcaa tttttggaga atctcatgga aatgctatag gtataaatat
    21361 agatggtctt ccttcgggga ttgaacttga ccttgataat attgataaag aaatgaagag
    21421 aagagcacct ggaaaaaatt ctatatctac ttcaagaaat gaaagtgata taccagaaat
    21481 tctaagtgga tattttaatg gaagaactac aggaacgcca ttatgtgcaa tcataagaaa
    21541 tagtgatact cgttcaaaag attatggaga gcttaaaaac ttaatgagac caggacatgc
    21601 agatttcaca ggtaatgtga gatattctgg atttaatgac tatagaggtg gaggtcattt
    21661 ttcaggtagg ataacagctc cattagtatt ttgtggggct atatgtaaac aaattttatc
    21721 acaaaaagga atagagatag gagcacacat aaaaaaaatt aaaaatatag aagatatgag
    21781 ttttgattat gtaaatattt caaaacaaca gttatcaaat ttgcaaactt tggaactacc
    21841 tttacttgat ttatcaaagg aagaagccat gaaaaatacg attatagatg caaaaaatca
    21901 aggagattca gttggtggta taattgagtg tgcagtagta ggtattaatg tagggcttgg
    21961 aaatccattt tttgactctg ttgaatctac tttatcacat ttattgtttt ctgttcctgc
    22021 tgtaaaaggt gtagagtttg gtttaggttt tgaacttgca gatatgtatg ggtctcaaag
    22081 taatgatgaa atgtattatg aaggaaatca agttaagagc aaaacaaata acaatggagg
    22141 aattatagga gggattacta ctggaatgcc aataattttc aaagtggcaa ttaagccaac
    22201 tccatcaatt agcagacaac aaaacacagt taatataaaa gataaaaagg acgatatttt
    22261 atatattaaa ggcagacatg acccttgtat agttcaaagg gctatacctg taatagaagc
    22321 cgtaacagcc attggaattt ttgatttgat gaaaggacga taataatgga ggatttaacg
    22381 agatatagaa atgagattga caatatagat aaagagctta ttcaattatt tgaaaagaga
    22441 atgaatacag ttcttgaaat tgccagacat aaaatgaaaa ataacactac tatacttcaa
    22501 aaagatagag aagaaaaagt actaagtaga gccgtagata atttagataa taaagcatat
    22561 tcacaagaaa cggtacagtt ttttaattct ataatggaaa ttagtagagg attacaaaaa
    22621 agattgatag ataatgatgg tgagcagaaa atcgagttta gtttagattc atcaaataag
    22681 aaatttgatt tgtcaaatgt aaataaatat aagtctttaa aagatgaatt aaataaaaaa
    22741 aatatcctag taggatttcc tggaaaatca ggttcattta cagaagaagc actaaataaa
    22801 ttcttcaaca aaaaaatatc aaaaaaacaa tttaaagaat ttgaagatgt tttcatagca
    22861 cttaaaaata aagaaataaa ctatggaata atccccatag aaaattcatc tacaggagct
    22921 atctctgaaa cttatgacct tttgagaaag tacggttttt atatagttgg agaagaatgt
    22981 ataaaaatag accaaaattt aatagggata aaagacacaa agcttgaaga tataaaagaa
    23041 atatattctc atccacaagg tataggacaa tgtagtgaat ttttaaaaca aaatagtaca
    23101 tggaaattga taccatttaa taacacagca acaagtgcag aacttgtaag aaaacttcaa
    23161 gataaaacaa aagcagcaat tgcaagcaaa aaagctgcaa gtatttatgg attagaaata
    23221 ataagtcatt gtataaatga tataacaaat aactatacaa gatttgtagt aatcagtaat
    23281 caaatacaca ttgaagaaga atcaaacaaa atgagtgtag tattttctgt tgaacatgaa
    23341 gcaggaaaac tttataaagt acttggatac tttgctaaaa ataatataaa tatgacaaaa
    23401 atagaatcaa gacctatgaa aaatgcctca tggagatatt tcttttatat agattttgag
    23461 tgttctatat acaatgctaa agtgtacgat ttattagaat tgatagaaca taatacagca
    23521 tattttaaat ttatgggagt atataaaaat aaaactgaat agataagata aatttttatt
    23581 taatttataa ttattaggag gtgtaagtat gaattttttt ggtctagtag gtgaaaaact
    23641 ctctcacagt gtttcacctc gaatccacaa gagagtattc gagatattga atattgaaag
    23701 tgcttataaa aactttgaaa tttcaaaaga agatatatct aagctagacg gtgctataaa
    23761 attattagga atacaaggag taaatgttac tgtaccatat aaggagcgta ttatgaaata
    23821 tcttgatttt atatcaccag aggcaaaacg tataggagca gttaatacaa ttttactcag
    23881 agaaaatatg ttatatggtt acaatacaga ttactttggt cttgatagta tgtttaaaat
    23941 ggctaatatt gatgttcaag gaaaagtagc agttatatta ggaactggag gtgcttctaa
    24001 agctgctctt acatatttta ttgattctgg tatagaaaag ctttatgttt caactagaaa
    24061 aaaggatgat aaaaaattat taaatagtaa agctatatta atagattatg aagaacttaa
    24121 acatataaaa ggagatataa tattaaatgc tacaccagta ggtatgtacc ctaatgtagg
    24181 aatttcacca gtgtcaaaat ctattataca aaattttgat atattaatag atttaattta
    24241 caatcctgga gaaacagagt ttttaagaat tggtaatagt atgggtaaaa aaacttgtga
    24301 tggattatat atgctggtag ggcaagcaat aaaatctcag gaaatttggc aagatactaa
    24361 aatagataat agtattttag atgttatata taatgaacta aaattagaat ttttgtaagg
    24421 gagattgtta tgataaataa aacaaaagaa aaattgatat taataggtat gccaggtagt
    24481 ggaaaaacta caattggtaa acttttggcc aaagaatata attgtagttt ctgtgatatg
    24541 gatgattata taattcaaat atctcaaaaa agtatagcag agttgttttc agaaggagaa
    24601 gatatcttta ggaactatga gactcaagca tgtagagaac tttctataag tgataaaaca
    24661 gtgatatcta caggtggagg tgtaataaaa aaggatgtta atatggaaat actaaaagaa
    24721 acaggtataa taatttttat tgatagacct atacaaaaga ttttggaaga tataaatatt
    24781 aattcaagac cattattaaa aaacggaaaa gatagattgt ataatcttta taatgagaga
    24841 ataaatcttt ataaaaagtt ttcagatata gagattttaa atgataaatc attaaataat
    24901 gctgtatata atattacaaa tgcagtcagt gaaaatttta aatttgactt taaagaaaaa
    24961 taatctaggg ggaaataaaa ataatgaata ttgttattgt aggactagga gttataggag
    25021 gctcttttgc taaagcatta aaaaaagctg gatatgaaaa tgtatttgga gtagatgtag
    25081 atttagaaac tttaaaaaaa gcagaaaaag caaaaatcat aaaaaaagga tgtactacag
    25141 gtaaagagtt atttaaaaaa gctgatttaa ttatactatc tatatatcct agattagttg
    25201 tagattttct aaataataat aaaaactttt ttaaaaaagg aactataatt actgatacta
    25261 caggaataaa agaaacgctt atcaatgatg tgttgcaaat tattccagat gatatagatt
    25321 ttatatttgg acatccaatg gcaggtaggg aaaaaaaggg tattgatttt gcaagtgaac
    25381 aagtttttaa tggtgcaaat tatataatta ctccaactgg cagaaacaac ataaaaaatt
    25441 tagagttagt tgaaaattta attttagaga ttggatttaa aagagtaaaa aagttaactt
    25501 cacaaaaaca tgatgagatt atagctttta cttctcagtt acctcatgtt atggcagttg
    25561 ctcttataaa tagtgatgaa gaaggtagag atacgggtaa atttattgga gatagttata
    25621 gagatttaac tagaattgca aatatgaatg aagacttatg gagtgaactt tttttaggaa
    25681 atagagataa tttactaaaa gttatagaaa actttgaatc agaagtaaat ttagtaaaag
    25741 aagctatatt taacaatgat aaaaataaat taatagagta ttttaaaaaa tcatcaataa
    25801 gaagagaagc tttagaaaaa taaatattaa tatttaagct atatatagat gggtataaat
    25861 ataagcgata gtgtatttaa ttgtattaat aaatatggat tcaatataat taaatatgct
    25921 attgatatat ttgtaccctt aactattgtt atcttttaaa tgataatgat atttatttaa
    25981 atactcttta ttaacaattt ataaaactta attgtaaaaa atacttatta atagtaaaat
    26041 aaagtgaatc aattatatta taattgctaa agagagtgag gtgtagctat ttgaaaaaaa
    26101 atagattaat agcaaagaat atatcaatag catttatagt actattcttt tttagtgtat
    26161 ttacattctt ttatgtaggt aatattaata gagtgttaga gtatgaaaca aatgacataa
    26221 taacagttac aattgctgga tggattatac tttcattttt atttttaggt attataattt
    26281 acatattata ttcaaaagca aatagtcaaa aaactataga aaaagtagca tatacggatt
    26341 ttgtaacagg ttattccaac tggagaaagt ttgaattaga tgttacaaat ttattaaaga
    26401 aaacatcaca aaataataaa tatgcaatgg tcatattcga tattgataaa tttaaagcaa
    26461 ttaatgatat atatggtcat aaaaagggaa atttaatatt aaaagatatt gcagatactt
    26521 taaatgaatt gactaatatc aatgaaactt ttgctcgtgt aagtgctgat aattttaata
    26581 tattattaac atataacaaa aaagaggata taataaatat tatcaaaaag attatggcaa
    26641 ataatgaact tgtaaactta tcttttggaa tttatgaaat caaagataag gatttatctg
    26701 taagtgtata tagtgataga gcttcacttg caaaatcatc aataaaaaat aatagtgatg
    26761 taaattttgc attttttaat gataaattaa gagagaaatt attacttgaa gataagatag
    26821 aaaaagaaat ggaatatgct cttgaaagtg ggcaattcgt aatgtattta caaccaaaat
    26881 acaatattaa attagataaa ttttgtggaa gtgaagccct agtcagatgg caatatacag
    26941 aaaaagaggt catatatcca ggtgatttta ttcctatatt tgaaaaaaat ggatttatta
    27001 gaaagattga tatgtacata ttagaacaag cttgtaaaga aatccggtct ttatttgata
    27061 aaggaatttc acctttacct atatctgtaa acttctcaag agttgatttt tttaaaaaag
    27121 attttattga aaacatagta aatatatgtg atagatataa aataccatat agtttaatag
    27181 aaattgaaat tactgaatct agtatgtttg gagatactga tactctattt aatgttagta
    27241 gaaacctaca ggatattggc tttatagttg caatggatga ttttggctcg ggatattctt
    27301 ctgtaaatat gcttaaaaat ataccattaa atgtaataaa attagataga ggattttttg
    27361 ttgatgataa agatgttgat aagagtcaaa ttgttataaa aagcatagtt tctctcatta
    27421 agcaattagg aataagggtt gttgctgaag gaattgaaac aagaagtcaa atagaaatgt
    27481 taaaaaaagc aaattgtgat attgttcaag gatattattt ttcaaaacca ttaccaatta
    27541 aagaatttga aaaattagtc tataaaatat agtcagcgag tcttaaatgg gaggtggtga
    27601 ttaagtgata agagcaaaat cgttaaaaaa tgtactgagt attgttttaa tatttttatt
    27661 tacaataatt tctttttctg attttgcatt taaaactaat gtccaggaag aagaaaatag
    27721 taaaattaat ttaagggaaa tatccctaca aagttccaat gctataaaaa taaaattaga
    27781 tagttctcta tcctttatta aaagtgtggc aaatatggtt tcttatttta atactataga
    27841 taactcaaaa atagttccat tattagctaa tatatcaaaa gaatctgact ttcaaagaat
    27901 ctctattgta tctcctgatg gaataagtca taccagcgat ggcaaaatta tcaatgtgtc
    27961 aaaatatcag tattttaaga aagctattaa aggagaaagt aatatatctg aagttgtgaa
    28021 atctccaatt gatggaaaag atacttttgt tatagctact cctgtattta ataagaataa
    28081 caaaataatt ggtgttttat acggttctta ctacaatgat aaattagctg aatttataga
    28141 tataacaagt tttaatagtg aagggtacat agatatattt gaatctagtg gtcaatttgt
    28201 tttaaaatct tcacatacga acaaactgat taagtcaagt agtaatatat atgatatatt
    28261 taaaaaagct tcttttgatg atggttatag ctataaaaaa atatatgaag atacaaaaaa
    28321 taacaagagt ggctttacct catatgaata caaaggagaa aatcgttatg ctacttatac
    28381 acccattggt gtaaatgact ggtatgtaat ttctgtgata ccacaatata ctgtaagaag
    28441 aaacattgat aaaataaatc aattagcatt ttctcttatt tttaaggtat tcttattgtt
    28501 tattatgctt ataatatata ttatttataa aaacaataaa tctcagaaag atatactaaa
    28561 agctaacaaa gaaatctcat ctattacaaa tagcattcct ggaggagtac aaaagtgtac
    28621 cctgggtgaa acatgcaata ttaatttttt aagtgatgga tttatagagt tgtttggtta
    28681 tacaagagaa gaaataaaaa cattgtttaa taatgatttt tatagtttaa tacataaaga
    28741 tgatgttgaa agaataaaaa aagaaatttt taaacaactt tacaaaaata aaactattga
    28801 attagaatat aggattataa caaaaaatgg taatacagta tgggttttag ataaagggga
    28861 gcttataaca gaacctgatg gaaaagaata tttttgttgt gtaactgtag atattactag
    28921 aacaaaacag ttagaacaag agatggaaca aaaaaatcta gaacttgaaa tgatatcaga
    28981 aaatgtttta ggtggtataa ttataacaga atttaatgat gattttacta taaaatacac
    29041 taactctggt tatctttcaa tgattggata tacacgtgaa caattagaaa atgaacttaa
    29101 atacaaagcg tgtaatcttg ttttttatga agatagaaag aaggctcttg aaagtataca
    29161 acatcaatta aacacaaaag gaatagctgt atatcaacat agaataagaa gaagagatgg
    29221 taatattatc tgggtttcta taaaaggaag gcttattatt gatgatgatg gtattgaaaa
    29281 aggtatttgg attctaaatg atataacaga tttaaaaaat gcagaacaaa aacttaaaat
    29341 aaatgaagaa agatttagaa ttgcattaaa gcaaacatca aacactatat ttgagtatga
    29401 tataaaaaca aagtcacttt taaatactag taaagagctt gataaatata atatttataa
    29461 aattactaaa aacgttccat attctctagt agaatcagga gttattcata aagattttag
    29521 tgatgatttt ataaatatgt atgaaaatgt aataaatgga gcaaaaaaag caagttgtgt
    29581 agttaagatg aaacttccag atgaaaatta tatatggaat aaagttacct tgactactat
    29641 ttttgatgaa gatggtaatc ctgtaagagc aattggtata caggaagata taagcaaaca
    29701 aaaggaagca gagataagat ataatcaaga aggtaagtat cattcagcta tattgtcgga
    29761 agcaatgata acctatgaaa taaatgtatc aaaggatact tttatcaaag gaaatgaaag
    29821 ttggcaaaaa ccatttggaa ttaagcctga caataactat tctcaaatgg taaaaactat
    29881 agcaaatagt attgtacata aagacaataa agaaacattt ttaaatacat ttttatgtga
    29941 aaacttattg gatgcatata aaaataatgt gactgaaata aaattagaat atcgaagaat
    30001 gaatcaagaa aataaaatga tttgggtcat ttgtacaatg cacttaataa aagattctat
    30061 tacgaacgat ataaaagcac ttgcttatgt taaagatatt gacaagaaaa aaaatgaaga
    30121 aattagattg aaattaaaag ctgaaagaga tactcttaca ggattatata ataaaggtac
    30181 tacagaaaaa ttgattaatg atttcttgaa ctctgaggaa gcaagcttag gaatgcatgc
    30241 atttttaatt gttgatatag ataattttaa atctgtgaac gataatttag gacatgtatt
    30301 tggagataaa gtattatttg aagtttctaa aaagctaaaa cctatattta gaaaagatga
    30361 tatagtaggt agaattggtg gagatgaatt tatagtattc ttaaaaaata ttcagtcttt
    30421 tgagaatacc aaaaagaaag cagaaaaaat atgcgatata tttagaaatt cttatacaga
    30481 aaataaaaag acatataaaa tatctggaac agttggaatt tcatttgtac cagaacatgg
    30541 aactgtattt gaagaacttt ataaaaaagc agacatagca ctttattatg caaagagcaa
    30601 aggaaaagat aagtatgcac tttataatga ttgtatctac caaaatgaac ttgaaaataa
    30661 tataagtgaa aataatataa aattagcaga taaatgtgag aaatccaaac cagtacttaa
    30721 agaaattctt gattctattg ataactatat ctatatagtg aatccaaata cttatgaact
    30781 tctttttgtc aataataagg tgtctcgttt ggatttagag ataaaattag gagaaacctg
    30841 ttataaatca ctattaaaat ctgatagacc atgtaataat tgccctctta acggattaaa
    30901 agaaaataag cattcaaaat tcaaaataga gacaaataca tttggtaaaa atatcagtat
    30961 agcaagttgg attaattgca tagatggaga atacaactgt cttatagagt gtatagattc
    31021 ttctttatac aaaaataaat aaaaaaggac tatgaagata tgttaaatag tataactttg
    31081 atacttggta taatatttac aatttactat ttttatctca aaatagtttt tggaggaatt
    31141 tcatttagtg agattttctt agttgtagga attgtactaa ttatctatca aatatttaag
    31201 aaaaaaatta aagaaaagaa ggttttttat agggtgttaa aaataataat cagcattttt
    31261 ttaatagtat ttgtagttac tgagagtcta attatttttt atcctaaaaa tagtttagaa
    31321 tcaaaaagtg attatctctt aattttagga gcttctgtaa aaaagactac accaagtaca
    31381 accctgaagg gtaggttaga cactgcattg aaatacctaa aaattaatga taattgttat
    31441 gtggtagtat ctggtggtaa aggaagtgga gaaaaaataa ctgaggcaaa agctatgaaa
    31501 gattatctta taaaaaatgg tatagataaa aataggataa tagaagagga taaatccacg
    31561 aatacttatg agaattttaa atattcaaaa ttgaagatag aagaacatag tcaaagaaaa
    31621 ctaagcgatt taaaagtaaa aatagtaaca acagattttc atgttctcag aagtaaaata
    31681 ttagcatata gaaatggata taaaaatacg tctttttatg ctagtaaatc aaaactttca
    31741 tttgtaccaa cttactatac aagagaattt tttgcattat ggaaaacaat catttttgat
    31801 agataataaa taaaaagact agatataaac tcatatctag tcttttctat tcccttaatt
    31861 ctaatccatt ttccaacttt acttgttgta gaaatttcaa cattgggatt tacaagtaat
    31921 tgcttataag aagttttata ttttacgatt ccaaaatata attttccttc ataatccatt
    31981 ataaatccga atggtcttac tcttggttta ttatcttcaa ctgtagcaaa atagaatgtt
    32041 gaattttctt ttaaaaaatt cattattttt tcatgattaa atcctctttg tatcttatac
    32101 taatataata aatataaata aaatatttat aatactaata taaatcgata taaaaacaat
    32161 tacaatatta tattgattat tcaaaattat atataaaatt cagaaaaaaa ttagtttaca
    32221 taataaaaat aaagtcaact aaaattattg attttagatt aaagtaccag attaagcatt
    32281 taagtagatt ttaagcttga tttgattaga aaggtacaaa ctatcaccga aaaaaattaa
    32341 acccatttaa aaagcaatat aaaagcttgt tatttttgag aaaaatagac cctctaaact
    32401 caattagata aaaataaaat acagaaaatt atatctctga atatctcaag taattaattt
    32461 tgaattttac gatattttgt ttgatgattt ataatataaa agcatactct taatctgctc
    32521 aaattaaaaa gaataaaaaa taacaaaaaa atcactgaca tttcactgac aaattgtatt
    32581 tttattatta taaatacatt gaaaatactt gattattgaa aaatggcata aaataataca
    32641 ttttatgcca tttactatta tttgatagtt tttaacttat gacataagat attttttaac
    32701 atatacaata aaatataaaa aaattgatat tgcaaataaa aaaaatacat attagatgtt
    32761 atagaaaaaa agcgcactta taggcttaaa atgtcacata aaagagtttt aaagaataat
    32821 atattatgaa cacaaatttt gtaatcacaa aggagtgata atatggcaac agtatcagga
    32881 caaatagttt ttgatagaaa tagaagtgct accattgatt ctggagactc aggaatagcc
    32941 aatataccag ttgtattaca agatatagca actggagtta gacttgtggt tctcacagat
    33001 gcatcaggaa attatgtttt tactaatgtt ccaaatggta actatagaat tgtagaagct
    33061 tttggaacta caggaggagt accaacacca ggaaattttg caacagcgat agtaggtcca
    33121 gttccaattg cagaaatgcc acctattagt tctgtgacaa atcctcctat tggttcaaca
    33181 aacttagatg gtacaacacc taacacacta ttaataacag tagcaggttc agatataaca
    33241 aatcaaaata tattaaatgg gcctgtgatt tatacaccta tagagaatat attggattct
    33301 tgcgtatctg tatctaatat aaaccttatt acagatgcag ataacggaac atttggtttt
    33361 tttccaccag gtacaccaag taatacagga cctgaaatag aaccttaccc aaatgtgacg
    33421 ccagatttta cgtatgttgt accagaccca actaagttta cacctttaga tggagaatat
    33481 acagtacaaa atattatgac aaatgcaatg agtaatgtta taggagcttg gtggcgtatt
    33541 gctgaccata ctacaggaaa tgaaacagga agaatgatgg tggtaaatgg ttttaatcct
    33601 ggagctgtat tttttaaatc aacagtacaa gttacaccta acactaatta tttatttagc
    33661 acttggattt taaacctttt taaggtaaca ggatatccac caccacagct aggtgtaaga
    33721 atatttgacc aaaataataa tatactatat caagcaacat taggagctca aattccagtt
    33781 aatacaaacg caccagaatg gaaagaagta ggtactgtga ttaattctca aaataataat
    33841 caacttacag tagaattttt tagtgaagga gaaagcgcca ttggaaatga ctatgctata
    33901 gatgatgttt ctttaagaga aatagctgtt ccaactttta ctccaataaa aacaagtaac
    33961 acagaaactg ctaatgtagg tgatataatc acatatacag ttacattaga taatacttgt
    34021 gatagccctt taactaatgt attttttagg gatttaattc caaatggttt agagtttata
    34081 cctggaactg taacggttga tggagtatct gtaccaggag tagaccctaa tacaggtttc
    34141 ccacttccag atattggagg aggaacaggg gttgaagtaa cttttgatgt tgtggttgaa
    34201 agtattccta acccaaatcc tactaataat atagctaata tagattactc ttatacacct
    34261 gtagaaggcg gtataccaaa tgatttttca gtagattcta atccagttcc tgttgaagta
    34321 atatcagcag atattgaagt tacaaaatta tctgaaccta ctatagtgaa tccaggagag
    34381 gaattaatat acactataaa agtagtaaat aatggaccat tcccatctga gaatgtggtt
    34441 ttaacagatg atgtaccagc ttctattata aatccagagt attcattaga tggaggagta
    34501 acttttcaac catggaatgg aagtttaaat atagggacat tagaagtagg agagacaaga
    34561 gttattataa ttaggggtat tgtaaatcca tcaacagtag gaattataac aaatacagct
    34621 gtagtatctt caactacagc agacccaaac cttaataata atacatctac aatagagaca
    34681 gaagtgaatt tattagcaga tattttagta atgaaaacag cagaacctaa ttcagctgtt
    34741 ccaggtactt tattgagata tactattcaa gtagaaaact taggaccagc aaatgctgaa
    34801 aatgtaatat taaatgatga tattccagct tctattataa atccagaata ttcattggat
    34861 ggaggagcaa gttttcaacc atggaatgga agtcttaata taggaacttt aaactctgga
    34921 atttcattaa cagttttaat tcaaggaaca gttagtttaa attcttcaga atatatagta
    34981 aatacagcaa cagtttcttc aactacacct gacccagatt taagcaacaa tatatctacc
    35041 attattacac cagttaaccc acaagcaggt atttctatta taaaagtagc tgacgaggat
    35101 gtagctgttc caggagaaga atttgtatat acaattgaaa tttttaatga aggaccatct
    35161 aatgctacga atgtagtttt aacagatgat ataccagatg ttattttaaa tccagaatat
    35221 tcattggatg gaggagcaac tttccaacca tggactggaa gtcttaatat aggtacagtt
    35281 gcaccagggc aattaataag aattatcata aagggattag taagttcaac tgctacagga
    35341 gatattacta atacagcaga agtaagtgca gatgtaccag aaccagttac ggattcatca
    35401 acagtgacaa ctcctatagt tgcatcagca gatatagaag taataaaaac tagcaatatg
    35461 gatacagcag ttccaggaga aacttttagt tatactataa cagttacaaa tttaggacca
    35521 tctgctgcac aaagtatcgt tttgacagat gatataccag atgttatttt aaatccagag
    35581 tattcattgg atggaggagt aactttccaa ccatggaatg gaaatcttag tataggcact
    35641 ttggatgctg gagaaataag aagtattata ataagaggaa cagtgagcca gacagcagta
    35701 ggtacaatta taaatacagc aacaataagt tcacctacac ctgacccaaa tccagataat
    35761 aatacttcaa cagatgaaac agatataagt tcattagcag atatttctgt gataaaaggc
    35821 aacgaaccag ttgctatacc agggggaaga tttatttatg gaattgaaat tgcaaatgca
    35881 ggaccatctt ttgcagagaa cgtaacttta acagataata taccagcttc tattttaaat
    35941 ccagagtact caatagataa tggagtgact ttccaaccat ggaatggaag ccttgatata
    36001 ggtactttag atgctggaga gataagaaat atcataataa ggggaacagt aagtcaaaca
    36061 gcaataggca caattataaa tacagcaaca gtaagttcaa ctacacctga cccaaatcta
    36121 aataataata cttcaacatc agaaatagat ataagttcat cagcagatat ttctgtaata
    36181 aaattagcaa ataaaacaga agcatgtgta ggagagcaaa tagattttgt aatagtagta
    36241 tcaaatgcag gaccagaaaa tgctcaaaat gttactttaa tagacaatgt tttagataag
    36301 cttaagaaag cagtattttc acttgataga ggtgtaagtt tccaaccatg gactggaagt
    36361 cttaatatag gtacactacc agctggaact ttaagagtta ttctattaag aggaattata
    36421 aaatcaacat gtcttgatag attaacaaat attgcagaag ttacttcaac aacaccagat
    36481 tcaaacctta acaataatat atcaagagtg caagtagaaa taaaacaatg ttgttgtaat
    36541 gattgctgtt gtaacaactg tagtaattgt tgttgcaatg attgtggttg taaagattat
    36601 tgctgtaatt gttgtaaaaa tgacttttgg tgttgatttt ataaaataat tttgtataca
    36661 ttaaattaaa ctgaaataaa aaataaattc acatatgagt aaaatatttt ataaatatta
    36721 ataaattttc tatctttgat atggaccaca ttcgtaatac tagttattaa atgaagtggt
    36781 cctttttaat tcattaaaat tatttattct aattaaattt taaatgtatt aaataatttt
    36841 aattttttat aaaaaatatt catatgttat ttatattaaa gtttagatat ctaaaaatac
    36901 ttttagaatt tattatatta tgttaatttt ttatatctta taaggattgt atttttctaa
    36961 ctataagaat agtattatac ttatatttaa aaataaaaga attttattcc tattgtgtaa
    37021 agtgagaata ctattttctt atattggtat aataatagta aatctataat atagaaaaga
    37081 ggtatttcta gtatgcatga aaataaaaaa aatctattag acggaagctt agctcaatat
    37141 aatgatacag cagttccaaa aataccagta tttgctggta acgatataac ttcagaagtt
    37201 tattatttta aacctaatca agttcttaat gctcatagac accctaatgg tgaacaaata
    37261 tttgtgttcc taaaaggaga aggtaaaatg aaacttggtg agcatgaatg tgatgtaaaa
    37321 aacggcgata ctgtatttgt accaacagga gagtggcatg aaattaccaa tggaagcaat
    37381 gaagaaatgg tagccgttca aattacaaaa attaatgctg gagcagaata cagaggatag
    37441 atatataaat acagttagta ctttaatatc tattttatta tataaacttt aatctcaaat
    37501 ataaaaagag tcttttaaaa ggctcttttt atatttttgt taattttcat tataaaaaca
    37561 agaaaatatc tagctaaaac taatatattt tatttaatat tttttatagc attgtttgca
    37621 aactcagtat ttacgatatc tttataaggt gcttccttat ctagttcttt agcttctttc
    37681 ataacagtca tcaatttctt caaaccttcc tcttttaata caggattttg agaccatgca
    37741 tctattgatt tatatctatc tacaactgtt gttaaatctt ctaaagatat atcttcaaag
    37801 aaaggttgca tagccttagc tacttctttg ctagatgctt gttgaatcca taattgacct
    37861 ttataaacag catttgtaaa tctttgaatt aaatctttat tgtttttcat gtatgatctc
    37921 gtagtagagt atgctgtaaa aggtatttct ccagaatctt ttcctataga tgtaactata
    37981 tatccactac cttctttttc cattgctgtt gctgtaggtt caaatgctgt tgtaaagtca
    38041 ccctctccac ctgcaaaagc tccagccatt acaccaaatt gtacatcagt tcttacatta
    38101 acattgcctg cttttagatt ttctccaata gtaagacctt tttcttttag aacatattca
    38161 aaagtcatta gtggaactcc accttttcta ccacctaata tttcggttcc ttttaaatca
    38221 ttgtaagaga aattaggcat ttttttccta gcaactagaa aactaccatc tctttttgtc
    38281 aattgagcaa agttcactgc ataatcgttt ttgttttgat tatatacata tatagatgct
    38341 tcaggaccca ttaaacctac gtttgcttca cctgaaatca aagctgccat agttttatct
    38401 gcaccttggg tatttataag gtcaatcttt ataccttcat cttcaaagaa tcctttcgta
    38461 atagcagcat actgtggagc ataaaaaaca gagtgagtaa cttctgctat agttacttta
    38521 tccagatttt tagacgaaga agattcacct tttttgtcat tagagttaaa atcacatcca
    38581 gttagacata ttgtacttac aatgatagag cttgctattg cgactatttt tttaaacata
    38641 ataaatacct cccataagac atacgaatag tatatagtat taaaaattta ttgtagttgt
    38701 tacaaaaatg tatctatgct tataatattt ctacaaaaac ttaataataa ttttcagttt
    38761 tatgtttagt ttttttagta a
//
LOCUS       DAEORM030000037        38605 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.037, whole genome shotgun sequence.
ACCESSION   DAEORM030000037 DAEORM030000000
VERSION     DAEORM030000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 38605)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38605)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 38605)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38605
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.037"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            415..1686
                     /gene="hflX"
                     /locus_tag="KRH23_002393"
     CDS             415..1686
                     /gene="hflX"
                     /locus_tag="KRH23_002393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HHS5225671.1"
                     /translation="MAKKGITVGLNINNKSEDFNELMIELENLCSACDIDVVGSITQN
                     AKQVNRAFYIGTGKVEEILNLIKKENIEIVIFYNELSTSQLKNLEEKLNCEIIDRTAL
                     ILDIFAQRAKTREAKLQVEVASLKYMLPRLIGSNENLGRQSGGVGTKNRGSGEKKLEL
                     DRRRIEEKITSLNRELDDLKFQRETQRSMRRKSNLPNVALVGYTNAGKSSIMNKLVDI
                     FKNSEEKKVFEKNMLFATLETSVRNIVLANNKEFLLSDTVGFVSNLPHDLVKAFRSTL
                     EEACEADVLLHVIDISNPSYKSHIKVTEDTLKQIGADGIPMIHVYNKIDLIDVEVLDR
                     ILDSIDKEGIFVSVKKDINIDKMIKCICDSIFKDYVRCKFLIPYDKGHVVSYFNENTS
                     IINTEYREDGAILDVECSNIEYNKYKKYALE"
     gene            1919..2416
                     /locus_tag="KRH23_002394"
     CDS             1919..2416
                     /locus_tag="KRH23_002394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HHS5225672.1"
                     /translation="MDAETLMKKYMVDDDSRKQAIFASIFVMQNKLQTTCDKLDPELT
                     MKQWLLLAIADSVDETLTLTKLGELMGCSRQNVKKLAIALEKKGFIEIEQNEKDSRAI
                     CLVTKDRVQEYSKKVRGMQEKVLQLLFEDFTEKEVEQLFFGIMKLSIGIENVKNYVEN
                     NDVGE"
     gene            2466..2990
                     /locus_tag="KRH23_002395"
     CDS             2466..2990
                     /locus_tag="KRH23_002395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin domain-containing protein"
                     /protein_id="HHS5225673.1"
                     /translation="MKNVVVIYKSKYGSTKKYAKWLSELLSCDIFETKNINIEKVMKY
                     DTIILGGGLYACNIAGISFLKKNYKELQKKNLVVFGVGAAPYDDEVIKKLREVNFKDE
                     LNKIPCFYCRGAWDETKMSFIDYTLCSFFKKSIAKKERQGLKPAEAPLLSGEAFDWCN
                     KENLTPILDYIREL"
     gene            3302..4666
                     /locus_tag="KRH23_002396"
     CDS             3302..4666
                     /locus_tag="KRH23_002396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase"
                     /protein_id="HHS5225674.1"
                     /translation="MDIKELVKMQRKYYNTGKTRDISFRIEQLKKLKLVVSQNEEKIL
                     LALKKDLNKSDFEGFMTEVGMFYSELNFAIKNIRKWSKIKRVKSSMVNFPSISKVVPQ
                     PYGVTLIMSPWNYPFQLALIPLVWSLSAGNCVILKPSEYSVSTSSVVKDIVEDTFSKE
                     YVAVVQGSQEESEKLLLERFDYIFFTGSTNVGRIIMKSASEHLTPITLELGGKSPCII
                     LKDANIDLTAKRLTWGKLINAGQTCVAPDYVLVHEDRKNELIEKIKYYTNKYFGDNPC
                     NNEQFPKIINQRHFNRILSLIDKDKIVYGGNYNKETLKIEPTIVDNVNWDDNIMKEEI
                     FGPIFPILTYKDLDEVIQKIIQMPNPLALYIFTKNKYLENKLLEMIPAGGCCINDTVT
                     HIATNYLPFGGIGESGMGSYHGKAGFDTFTHYKSVLKKLNLDVPIRYAPYDNKLIKVL
                     KKIM"
     gene            4805..5971
                     /locus_tag="KRH23_002397"
     CDS             4805..5971
                     /locus_tag="KRH23_002397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HHS5225675.1"
                     /translation="MKINWNTKYTTIAIYTFIIAASSIIFYLVSSQIDVFSNNLDAIF
                     TTLQPFIIGFAIAYLLNFILKFYEDRIFIKSEKLKKLKQSSKRGLGLLLTYATATLIL
                     YLFMHFVLPQVIESIVGLANDIPMYVNNATKLIDKLMTDLNLDEQYFNLAVDKWNEFV
                     TYIIKFVTDLIPILGSMLKNVASSIWNIVLGLIVSVYLLIDKEKFYGLSKKITYAVFT
                     EKQAARILELTHRSNYTFGRFLGGKILDSFIIGILTFVILTLVKMPYTLLISVIIGIT
                     NIIPFFGPLFGAIPSTLIVMFVSPIKAFWLLLIILIIQQIDGNIIGPKILGDSIGISA
                     FWILFSLLVAGKLLGFIGMVIGVPMFAVIYSIIKDIVESKLDKKGLPTDTSDYM"
     gene            6088..6870
                     /locus_tag="KRH23_002398"
     CDS             6088..6870
                     /locus_tag="KRH23_002398"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HHS5225676.1"
                     /translation="MAFIECKFKSKYTGGETDIIVILPVANGKELFSGKEIYDFEGKF
                     KTLYLFHGLEDDQSSWIRYTNVEHYAKNKNIALVIPRVETSFYTDMAYGHQYFTFVSE
                     ELPKFVRAIFPLSDKREDNFVAGMSMGGYGALKLALSKPKEFSAVASFSGSPDMIHEL
                     ENQQIETNADILFHDFGRPEDARNSENDLLYILKNLKERNEDIPKIYQFCGDRDFLYK
                     NNQMFKKYAESLGVDVEYEECVGGHEWRLWNLWIKKFIDIIG"
     gene            complement(6989..7642)
                     /locus_tag="KRH23_002399"
     CDS             complement(6989..7642)
                     /locus_tag="KRH23_002399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HHS5225677.1"
                     /translation="MSKSEKGKETKASIISAARELFFEQGYHKTTTRQIAERANINLG
                     LISYYFSSKSEIGAIIYEDIRNEMQSLIYNYHEEGTMMMFFLAMNADLCFLLKNEAYR
                     NFYLDIAYEEAILSYQRSVTEMVMKRYVNDKESIEHDELILSCIGILAMKPEIIRVYT
                     SHKYDISSQAVIKHFTKQFLINLGHSTDLCEEILEELSKYYIDIVDNFTPIITRVRT"
     gene            complement(7666..9030)
                     /locus_tag="KRH23_002400"
     CDS             complement(7666..9030)
                     /locus_tag="KRH23_002400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter family protein"
                     /protein_id="HHS5225678.1"
                     /translation="MLLLIVTCAIYIWIGFYFSKKVKTASDFLIAGRNLPLPILAATI
                     AATSFGGGCLVGGVQWGAERGLWVGMYSTIGAALACFINAFFAGKLRSLSCDITPADY
                     IETRYGHSVFLRAYQSLVTPISILAIMGSQLISFGSVSTAFGIPYDIAVIIGVIVIII
                     YTYTSGMWGVAVSAFIQLAICIVFLPIVAYISLKLVGDNPLLMLQSMVKEPFFPGNKS
                     ISDFMYTVLPLVLGSIFSYESFLRYQCADNAKNAVKSSVIAGFILLFLAFPIGIIGAI
                     GGSLFPNISSVQVLPQMISTTLPPLISVLFLAAILAAIMSTADSLMTSMSAIISRDIY
                     NKLLHPNIEFNDLKNTLKYSQIASALTAIIGAIIALKFDSLLELLFWPAPLCTGVIFA
                     PFVIGLCWKGATKKGAIYAVIVSVILALLNMIGILTVFDRILVPIIGGSITIFIVSKF
                     SKKD"
     gene            9687..11117
                     /locus_tag="KRH23_002401"
     CDS             9687..11117
                     /locus_tag="KRH23_002401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HHS5225679.1"
                     /translation="MSSQESKPKGNLISNFRDDMRDPKKRAIYTYSSSINLAYNFIGY
                     FVSTVTNIFLTDVAKLGVIMAGGMQIIQSFIKIAVAPITGTVFDKQPFKKGKYYPWLR
                     YAPAALALTYGIFFIVPLMKISPALLLPLMTALLLIASCAQQVVFTIIYAIYPVVAKT
                     PRDRVIGSTTTNIFKEVGKFLVGFSYPLLLVLFADVLGGEGMGYLGTYLFFAAGCLLV
                     FWFSSTEIIKSGAEEEVLQKEEKPKIKASEMAKALFTNVPLMMAFCLEFLICIRSIGL
                     GPLAPYYFKYVIEDERGLAVFLSIMPLVSVAFMFFAPVFIKICREQKLASIISFSICA
                     LCHLLVAWTPWGKTTLGVTMLLAIGGGFSNVVSIINLNFFAGSCDYGHWKSGKDLPGL
                     SMSLYPVAIQVGVLLATTIRTVLMNSMGYQADMVVTEAVKSGFINMISYSMAIPLIIA
                     VVIAILYPVSDKKLNQIREELNQRNA"
     gene            11220..12323
                     /gene="hisC"
                     /locus_tag="KRH23_002402"
     CDS             11220..12323
                     /gene="hisC"
                     /locus_tag="KRH23_002402"
                     /EC_number="2.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004400 - histidinol-phosphate
                     transaminase activity [Evidence IEA];
                     GO_process: GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphate transaminase"
                     /protein_id="HHS5225680.1"
                     /translation="MIEKLLRNTVKELHQYVPGEPVEKVKEKYGVKEIIKLASNENPL
                     GPSPKAIEAMIEMLKQGQLYPEPEANELRRKLAEKLDLKPENFIVANGADNVITLIGE
                     AFINRGDEVIYCNPTFPSYRTATIKNEGIPVEVPLTEDYKYDLQGILDKITDKTKLIC
                     VCNPNNPTGTIVDDKELEEFLKKVPENIITILDEAYIEFLTVPNYVDGLKYVRENYNV
                     IVTRTFSKIYGLAGLRVGYGIAKDEIIRTLFTVKEPFSANRVAISGATAALDDEEFIK
                     ETYELNRVGMAYFKEEFTKMGFDVVDSQSNFLYVDMKTDIPKLFEDLKKRGFVIRPSA
                     THARVSIGTMEENKKFVAVLKEILNIKGEPSIG"
     gene            12356..12574
                     /locus_tag="KRH23_002403"
     CDS             12356..12574
                     /locus_tag="KRH23_002403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HHS5225681.1"
                     /translation="MNLKINAERCKSCEYCVISCKKGALKISSKINKEGYAHVEVDES
                     KCILCGICYQVCPDNVFEIIKEEACQEA"
     gene            12591..13640
                     /gene="vorB"
                     /locus_tag="KRH23_002404"
     CDS             12591..13640
                     /gene="vorB"
                     /locus_tag="KRH23_002404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate dehydrogenase subunit
                     VorB"
                     /protein_id="HHS5225682.1"
                     /translation="MKKMWKGNHAIAEAALRGGCEFYAGYPITPQTEVMEFLSHRMSE
                     LGRTFIQSENEMAAIYMVYGAYASGMRSMTSSSGPGISLKQEGISYLCANHYPCVIVN
                     VQRWGPGLGSLDSAQTDYLRDTRGGGNGDYHLIVYAPNSIQETVDLMYNSFDVAEKYR
                     VPVEILTEAALGQMMEPVEFPEFKKREGDLGWTYDGSNRDHAKVADNQKPTFCMEKRM
                     RITENEQQWEDYQVEDAEYVFVAFGIPSRTTMNAVRRLREQGEKVGIIRPITVWPFPY
                     KAFEKVSKDVKGFISVESTDTGQLVEDVALASKKVCKENVPVYGLFSGNHIPKTLQVM
                     DTYSKIKSGEIKEVF"
     gene            13642..14382
                     /locus_tag="KRH23_002405"
     CDS             13642..14382
                     /locus_tag="KRH23_002405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent enzyme"
                     /protein_id="HHS5225683.1"
                     /translation="MATEKLTPSVVSIPNKFCPGCGHGIVNRIIAEVIEEHGYEKNHV
                     LTLGVGCVCNMNFSWNGDKMQTAHGRASSTAIGVKVALPDTLVMTYQGDGDAYVIGLS
                     ETLNTAYRNHNVTVFVINNNNFAMTGGQMSWTTMPGQVTTTSVNGRDIKTTGSPLKVP
                     EMVANFFDVAYVARGSVHSPKEIINLKKYIKNAIEAQLNGEGYSLVEILAPCPTNWGV
                     SLEKSIKWMEEEIVPYYALGEFKQRDGE"
     gene            14385..14924
                     /locus_tag="KRH23_002406"
     CDS             14385..14924
                     /locus_tag="KRH23_002406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016903 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoacid:acceptor oxidoreductase family
                     protein"
                     /protein_id="HHS5225684.1"
                     /translation="MEKELVFAGFGGQGVLTLGLIVAESALELGKQVTWMPAYGPTMR
                     GGKAYSVVKFSDESIGGPDMEEIDVLVAMNKPSLDYINLVKEGGTVVINTSAIDENVT
                     LREDISVVKINCQELAQKVNNPKAANIVVLGALIAKTGLFEKELALKTMCDFFEEKGK
                     GKFNVQNEAAFMEGYNNAI"
     gene            15048..17147
                     /locus_tag="KRH23_002407"
     CDS             15048..17147
                     /locus_tag="KRH23_002407"
                     /EC_number="6.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0043758 - acetate-CoA ligase (ADP-forming)
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetate--CoA ligase family protein"
                     /protein_id="HHS5225685.1"
                     /translation="MSLEKLIRPKSIAIVGVTDKLGFGRSAALSIVKSKETDRVYYVN
                     PKREELFGRKCYKTIQEVPEVVDCVVVCTPRNVVPSVLKDSGELGTKAAVVYASGFAE
                     EGTEEGTDLENQLIEISNTYDMKILGPNCMGLLNCIDKVNLWAGGSKWDLDTKKPGIG
                     IVGQSGFITAEIVSSDYFNISYGFSTGNGNIVTLEDAVDFLVDDDYASVIAIYLEGLK
                     NPQKFIDALKRAAQKRKPVIILKSGRSEKGAISAASHTGNLAGSSKAFESIFEKYGVI
                     SVENLEQFMCLAQAFSVLDGNLPANSNFAAINFSGGENTICADLAEENGVELAEISSE
                     TKEEMKKYLPGFATPKNPLDATTALFHEKDMIVGLLHTFEKDDSVGFTMVGANIRDEE
                     NEMHETLCKAVSEAREQGLKKPVFAVPTLEGNRYLDYRTRLEDNQVPIMSSVGTTFTC
                     FNKMAKFIDYDYSKRTLEFKAVKKRESNNVVALSELDSKIEMKKYGVPVPGQGNAKSI
                     DELDEILKYIKYPVVLKINSSEILHKSDVGGVKIGIKNRDEAVDAYNEILTNVKKAKP
                     DANIDGILVQEMVESGIEIIIGITNDDQFGPMLLVGLGGVFVEVFKDTTLYPLPINHD
                     EAIMMLKKLKSFKLLNGYRGSEPCDIDALADMMVKLGKYAYENKDEVKEIDLNPVFVY
                     PKGKGVCAVDALIVKYK"
     gene            complement(17414..17929)
                     /locus_tag="KRH23_002408"
     CDS             complement(17414..17929)
                     /locus_tag="KRH23_002408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferritin"
                     /protein_id="HHS5225686.1"
                     /translation="MISAKMEKLLNEQINHELYSAYLYLSMSSYLEAEGLKGFSNWFY
                     VQYKEETDHAMFFYKYLHNVGGKVQLDAIPMPDSDFTSAMDILERTLAHEKKVTALIN
                     NLAAVANSESDFRTSQFLLWFISEQAEEETNCEDNIKRVKLAGEGGLFFVDQEFANRT
                     YAAPTNPPVTI"
     gene            complement(18021..19232)
                     /locus_tag="KRH23_002409"
     CDS             complement(18021..19232)
                     /locus_tag="KRH23_002409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HHS5225687.1"
                     /translation="MSNKQGSNIKDVKIKNKLIILKLLSTNTPMSRVDLAKSTGLTKM
                     TLSNLVTELINENMIREIESSTLNAHSSGRKPILLDISNISPCICGILIRRNICKVII
                     SDLKGNIVKQLSETYPKFLSNDVLKDIIKRMFTKIMKINKRDIIGIGISSIGPVDDIN
                     GTILNPPDFGNVSNLNIVDFIKEMSDLPIFLINDANSGALAEKMYGLGKNISNYIYLH
                     IMNGIGAGLVLENKLHTGNLGQSGEIGHTSINFSGPLCSCGNNGCLDYYTSVSNLIKR
                     IESLSHIYPNSPLINCKDFSLVKLIDEANNKDSLAMFLLDEFCTYVSYALVNTLTLID
                     CSSIIIGYDFNIPGTFIENTLLKKLTASASFSKYKKISVRHSNFGANAPLIGSIAIVS
                     YNFFNGSINFY"
     gene            19908..21350
                     /locus_tag="KRH23_002410"
     CDS             19908..21350
                     /locus_tag="KRH23_002410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HHS5225688.1"
                     /translation="MRTIRRVLALGLTLAIFLINVPNVDALTSDTIKGNNIYETAGLI
                     ADKKSYDTAIMVNMDNSIADGLSASGLAGAVDAPILLAQKNKIPNETKQRLKNVKKIY
                     IIGKELSISKSVETELKNTGAQVTRLGGDDRIKTSYSVAKEVNGIKKVDEVILTNAYK
                     GEADTISAAPVSVRDIAPIVLTDGKSVPFSTSNVKTYAVGGSISMSTSLVNKTNAKRL
                     GGSDRYDTNKKVIKEFYSDASEFYLSDGYDLVNALTGSTIAKENPIVLVSESSDKSIL
                     AGADKITRLGSISDSVYNKCVSAAQNNGDSSTKGESPMKNETSILGQPTASLEACLKW
                     AKSKKANDLFIELIPILYDTAVQEGVNPVLAVAQSAKETGFCNFGGVLDASFKNPCGL
                     KTSVGGSDTDKNAHSRFDTWEEGILAQIQHLCLYAGQDGYPLSNPVDPRHEKSLFGKA
                     KTVESLSNNWAGGQYGQDLVRMMGEIEATK"
     gene            21392..21745
                     /locus_tag="KRH23_002411"
     CDS             21392..21745
                     /locus_tag="KRH23_002411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5225689.1"
                     /translation="MKKSNIFSIIFPTVIMVLMFLTFATDIFNIPDIQSKSIFVVGMV
                     LIFPISFLIQGIICVLNKTNWILSLIVSLVTYIVLMYIFLNDSAYIYVLLYTAFYMIG
                     HITAKLYYKIKTFKN"
     gene            21936..22757
                     /locus_tag="KRH23_002412"
     CDS             21936..22757
                     /locus_tag="KRH23_002412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004401 - histidinol-phosphatase activity
                     [Evidence IEA];
                     GO_process: GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphatase HisJ family protein"
                     /protein_id="HHS5225690.1"
                     /translation="MNLIDNHIHTNFSSDGKDSMEDTIKKAISIGVRYLTFTDHLEHD
                     EDRGFCINYNDYVPVFNKFKEKYKKDIELLLGVEVGYRKHLKNEIEEIINSNPFDFVL
                     CSTHTIDNVPVPSKEYFKGLSKEDAYYKYFNSILETNREFGDYNIYGHLDYISRYGIY
                     SDNRVIYNDFKDVIDEVLKSIINNGSGIELNTSGYRYGLNAIHPNEDILKRYKELGGF
                     IVTVGSDSHRVEDICKDFDVAYDMLKYLDFKYVSLFKERETYFVNIEKVKSNNIA"
     gene            23015..24898
                     /locus_tag="KRH23_002413"
     CDS             23015..24898
                     /locus_tag="KRH23_002413"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 13 protein"
                     /protein_id="HHS5225691.1"
                     /translation="MSNKNKENITLSNQIKGTIQNSLTKEAILHIPMSNYAYGYDRET
                     LHIRLRTKKNEAKRVILRIGDQYVWDKGGAGGGNLNASGVGWSGGTNIVMSKEVETEL
                     FDYWIAKCKPLNKRSRYGFIIEGQEEKLLFTEKRIIELGNENDEKELCEIGDFFGYPY
                     LNYIDIPKVPNWVKDTVWYQIFPDRFANGDPSINPEGVDKWGAIPTRDNFTGGDLQGV
                     IEHLDYLSDLGINGIYFCPITIGKTNHRYDTVDYMEVDPTLGDKETLKKLIEEAHKRN
                     IKIMLDAVFNHIGYYSKQWQDVVQNKENSRYKNWFYIKDMSKIDTPIEQIDEKNIPYE
                     TFGCEKYMPKLNTENSEVIKYLLDVGKYWIQEFDIDAWRLDVSNEVDHVFWRKFREEV
                     KKVKPDIYILGEIWHGSLPWLMGDQFDSVMNYLMSEAMKKFFCTDEINAEEFKYMIND
                     VMVSYPIQVSEVIFNLLGSHDTTRILTYANGNIDRFKLAYMFMFVQTGCPCIYYGDEI
                     GMEGELSSISEGQRKCMEWNEEKWNKDIFDFMKKIIRLRKENKELRSISNEWVLADKE
                     NGTIILKKESISIIINNSSKNIILTLPDYLANKKVKDLYEEEIVDLKEELMLEKYKFI
                     ILK"
     gene            25123..25803
                     /gene="pgmB"
                     /locus_tag="KRH23_002414"
     CDS             25123..25803
                     /gene="pgmB"
                     /locus_tag="KRH23_002414"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008801 - beta-phosphoglucomutase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HHS5225692.1"
                     /translation="MIEAFIFDLDGVITDTAYYHYMAWRKLAHKVGIDIDTKFNESLK
                     GISRMESLDRILEFGNKKYSFSEEEKVRMAEEKNNYYVSLIDEITSNDILPGIESLLI
                     DVKSNNIKIGLSSASKNAINVLNHLGISDKFDFIADAGKCKNNKPHPEIFLMSAKGLN
                     VNPQNCIGIEDASAGIDAINSANMFSVGVGNYENLKKANLVVDSTNQLKFEYIQEKYN
                     EYIVRRII"
     gene            25800..28085
                     /locus_tag="KRH23_002415"
     CDS             25800..28085
                     /locus_tag="KRH23_002415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HHS5225693.1"
                     /translation="MKCLFSNVDEWKIIQDKIEIKENRLAESIMSIGNGYMGMRGNYE
                     ENYSGDTHKGSYIAGVWFPDKTRVGWWKNGYPEYFGKIPNSVNYIGVRIFIDDVELDL
                     AKCKVEDFHRELDMKNGILNRRFIVNINDKKFEVRVTRFLSISVKELAVIKYSIKSLN
                     SNTKIKFVPYLDSNIKNEDSNYEEKFWNGISSSSLEYKGSILSRTKENAFNTPVFTVG
                     SMMYIKTNGDVEAVSHESDYNYCENSITMDVLKNEVASIEKYVSITSTRDYKESELLR
                     KCEDILNRELSKSYDDILNEHIKLWNKRWESADVKINGDKSSQQGIRYNLFQLFSTYY
                     GEDSRLNIGPKGFTGEKYGGATYWDTEAFCVPVYLGVADKEVTRNLLEYRYNQLEQAK
                     DNAKKLGLKGALYPMVTFDGVECHNEWEITFEEIHRNGSIVYAIYNYTNYTGDYKYIK
                     EKGIDVIIEIARFWASRVHLSTKKDLYMIHGVTGPNEYENNINNNWYTNYIAKWCLDY
                     AVENILRLEKECNECIDRNNVTREEVEFWKIISNKMYLPYDEELQIIIQNDNFLDKEF
                     VEVKDLPKENFPLNQNWSWDKILRSCFIKQADVLQGIYYFGNRFTKEEKKRNFDFYEK
                     YTVHESSLSSSIYSIIASEIDNLEKAYELYSRTARLDLDNYNNDTNDGLHITSMSGSW
                     LSIVHGFAGMRTWNETLSFDPKLPKEWKNYSFNINYRDNIINVDVCSDLIKIENLKGK
                     PIKIIVYGKKYILEKCIKIDK"
     gene            28311..29204
                     /locus_tag="KRH23_002416"
     CDS             28311..29204
                     /locus_tag="KRH23_002416"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HHS5225694.1"
                     /translation="MKNKKFIVIILIISILIGVLVKEYSSREIKKDDINVSKYIKYAD
                     LASKNNAQVNWKYVASIVAVLNKNNLKNVKDSQIQEVSDLFVKNFSKNNKINKLSDIL
                     DELEFSNRQKRLVDNYIDNLKDYGIKPERLKSDTKYMKFIDEIKTEAIQNYKDYKILP
                     SITIAQAIIESSWGKSTLAKQYNNLFGIKADAYWKGKSVTLETKEHLDTIIDDKFRIY
                     DDKNESIKDHAKFLATNKRYKNNGVFDAKTYIYQAKALEKAGYSTAKDENGNSIYAAR
                     LIELIQQYNLQLIDSEIQSEM"
     gene            29645..30136
                     /locus_tag="KRH23_002417"
     CDS             29645..30136
                     /locus_tag="KRH23_002417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5225695.1"
                     /translation="MYENNKVIYNLERCEKLEKTLYLSQFNTYKNFKLASKKTVINSL
                     ETYVYNMNINNISLVDTIECISLEDEQLTGKKLILVGDIDIDAILDYTGNKRNRNSSK
                     KNTFKLKIPFSTFIQMPRKIENKDKINLKYLIQDITSSILDDNLFISVTAIISYENSS
                     KIE"
     gene            30164..31111
                     /locus_tag="KRH23_002418"
     CDS             30164..31111
                     /locus_tag="KRH23_002418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5225696.1"
                     /translation="MRITKTTFNDVFSNDANGSIIKVEKYVDKKCASVFEILTYTIIV
                     TNTSRYKTGNIFFKDYISKYIEFINNTVKVNGIIKRGLDPQQGFYIGRIDASCKKIIS
                     FKSVVLPNSAHRIIKNSANIYYYYKCNLDKFPTRISIESNRVYTNVNKIVFKQLNISN
                     TLKAPKNLRDILKVNVNSKIFDVKPMKNLINKGSNLKLCNLIVFGCIEVEIDYSCKNR
                     SNFKTVNKSNDIKKDKYYKNDIQNNNENINDCKKQISFGDNKVKKITKTFGFSCFICS
                     PVGIIYEDMKNINIKIEHTSINELNPEELFVNTSLLLYY"
     gene            31401..31943
                     /locus_tag="KRH23_002419"
     CDS             31401..31943
                     /locus_tag="KRH23_002419"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008745 - N-acetylmuramoyl-L-alanine
                     amidase activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HHS5225697.1"
                     /translation="MKICITVGHSILKGGKSTGVNGIVDEYNYNKKLAPMLAEMLISQ
                     GNTVDVIICPERHFMSEREEFFYRVPKVNSGKYDLLVELHLNKADGTQCGTEVLYYGT
                     EGLEYAKRVSNRLGELFENRGAKKRENLYILRNTNPVAIQIESFFCDNVNDCNKANES
                     GYDYIARLITEGILNKDINM"
     gene            32271..33746
                     /locus_tag="KRH23_002420"
     CDS             32271..33746
                     /locus_tag="KRH23_002420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HHS5225698.1"
                     /translation="MKYTFEKFKLNEKILKSLKSLGYNIPSRVQREVIPKLLKGQNLV
                     VRSKTGSGKTASFAIPLCENISVDYNNIQALIVVPTRELALQVKDEISDIGRLKKVRC
                     SAIFGKQSIKDQIAELKQRVHIVVATPGRILDHINRGSIKLENVKYLVIDEADKMFNK
                     GFVEQMEKILLNLPKEKIVSLFSATINEEIKYICEKYMLDYSVINIEENESDTNQKTR
                     QIDDKIIKANGREKYILLKELIYSENPKSVIIFCNTKEKVSKLYNKMSKEGFLIRELH
                     ADLSQERRIFVIKDFKNQKFNVLVSSDVASRGIHIDDISLVINYDVPQDKENYIHRIG
                     RTGRKGNSGKAITIVTEKDEKYIENIETYIGYKINELKDIEKSRITHGKILFEEYSKG
                     ILKKVDKNSYKSKDIKLNIESEVVKLYLNAGKKKKIRVLDIVGAFSNIKGITNDDIGV
                     IEVQDLCSYVDILNYKGDLILKKYKEIPIKKKMVKVKRDIR"
     gene            33766..34053
                     /locus_tag="KRH23_002421"
     CDS             33766..34053
                     /locus_tag="KRH23_002421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5225699.1"
                     /translation="MLCYRNEVAKNTIEVVKDLKAEDMKRKVSPIDLERILVTGGVIK
                     HEDSIWLLDFWGNKDIAGILLMPPTRHVILHLNDCCKWKEYFRTKKKFYRS"
     gene            34209..34973
                     /locus_tag="KRH23_002422"
     CDS             34209..34973
                     /locus_tag="KRH23_002422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HHS5225700.1"
                     /translation="MAYFNYNDKQCYYNEIGDGTPLLFLHGNTASSKMFNDIINFYKD
                     EYKVILIDFVGHGKSQMVDKFSADLWFDEAMQVICFLEAMNYKKVNIIGSSGGALVAL
                     NVALERPDLVNKVIADSFEGEVPLESFVQNVKIEREASKQDDGAKAFYIYNQGENWEK
                     VVDNDTEAIFEHYKTIGKFFHKPLETMQPEVLLTGSREDEFVSLISSDFFENTFSLLL
                     EKIKNGKMYLFDKGGHPAILSNGLDFSNVAKKFLEE"
     gene            complement(35258..38437)
                     /locus_tag="KRH23_002423"
     CDS             complement(35258..38437)
                     /locus_tag="KRH23_002423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SNF2 helicase associated domain-containing
                     protein"
                     /protein_id="HHS5225701.1"
                     /translation="MKIDMIYKLIRRNTEPSRWSRGVKYYTNQLVDYIDIDIDDLQNN
                     LLTFRGGVNSEDNYSFYFNSITIDIKHFKIIENDCSCADCQSKGKSIFICKHIVAIVI
                     KSLKQIKNKKDVPPILIDILGADKDKLSNTNSKTSLDLSKQLLSLLDNTKRERVNLDV
                     LINVDSNKAIAEFKIGIDKMYILKNITEFAYSKLNGYELDFGKKFTYNPNIHYFADED
                     EKLVDIIEEYGTNLSYNFSSSHSKKFMEINASSLKQFLNAIKYKDFTLIFSKEEYHPK
                     ILNDTLPVRFDFKNIEDKIVLYSKDSLPVPLTKKNDVLLYDGNIYLLSHKKAHDYSKI
                     YQILSKTKELKFDKEDSKDVLGLLVPRLKSISQEVHLDDNIKNNITKDFKSEFYFDMI
                     DGNICCDVKYIYDDEDKKFVLPNIQKEATIENKLTSSQFTKENNHYVFKGTDHDLFTF
                     LDLQLESLKEFGDIYYSEKFKLKKIYNASSIQASINQTNQNYLEFNFNISDINPKEYK
                     DILKAFQEKRTFYKLKDGNFIDLSERETKDFFELVENLDIMDKSKNNKIHKNKALYIN
                     DVIRSKNLKFIDGKKELDSICEKFRNFDSINLEIPANLNANLRDYQINGLNWFKVLDY
                     YKFGGILADEMGLGKTIQTIAFLLSLSNKKSLIVTPTSLIYNWKNEFEKFAPDIKVLL
                     IHGNKRDREKCFMELENFDVILTTYGTLRNDLEKYSEIKFDYCILDEAQNIKNPVALV
                     TESVKSINAENKFALTGTPMENNLLELWSIFDFIMPGYLYSKAKFQELFINKEDNVKN
                     LKKLIKPFILRRSKKQVMKELPDKIEKNFFVELNKEQKKIYSVYSKDIQDKMKDKNLK
                     KDKIVIFSYLTKLRQLCLDPSIVVKDYNKKSSKIETCLEILRDSINENHKILLFSQFT
                     SVLKNISKELDKYKIKYHYIDGKTNAKERLELVDEFNNSMDKKVFLISLKAGGTGLNL
                     TSADMVIHFDPWWNPSVENQASDRAHRFGQKNSVQVIKLIAKGTIEEKIIKLQESKKE
                     LINQFINGELSNEGVLKSLSDEEIINLFN"
BASE COUNT        15121 a         4163 c         6381 g        12940 t
ORIGIN      
        1 ttgaagtata tgtttttatt acttttatta atcatgcaaa taactactta aatttaagaa
       61 tagggttaaa tataaaatga taattacata taagttaatt aaactaatgt atttttaata
      121 tatatttaga attttaatcc ttcttatgat ataagtagct tgttttgtat tacttagatt
      181 tgtaaggagt ttttttattg aaaaaactgc ataatatatt tgggaggagg tgtaagaaag
      241 tgatttttta tataagattg agaaaataat gcacgattat ggttattata atagtaaata
      301 agaagtgtca tttaaggata agataaaaag caaaattctt gatgaattta attatagagc
      361 cataatctcg tgctatagat taaataaaaa atagcagata aggagaatat ggatatggcg
      421 aaaaaaggaa taacagtagg attaaacata aataataaat ctgaggactt taatgaacta
      481 atgattgaac ttgaaaactt atgttcagca tgtgatattg atgttgtagg gagtataact
      541 caaaatgcaa agcaggttaa tagagcattt tacattggga caggtaaagt tgaggaaata
      601 ttaaacttaa taaagaaaga aaatatagag atagttatat tttacaatga actttctaca
      661 tcacaactaa aaaatcttga agaaaagctt aattgtgaaa ttatagatag aacggcattg
      721 atacttgata tatttgcaca aagggcaaaa actagagaag ctaaacttca agtagaagta
      781 gcaagtttaa aatatatgtt accaagactt ataggttcaa atgaaaattt aggacgtcaa
      841 agtggtggag ttggtactaa aaatagaggt tctggtgaga aaaaattaga acttgaccgt
      901 agaagaatag aagaaaagat aacatcttta aatagggagt tggatgattt aaaattccaa
      961 agagaaactc aaagaagtat gagaagaaaa tcaaatcttc caaatgtagc tctagtcggg
     1021 tatacaaatg ctggtaaatc ttcaataatg aataaactag tagatatatt taaaaactct
     1081 gaagaaaaga aagtgtttga gaaaaacatg ttatttgcta cacttgaaac ttctgtcaga
     1141 aatatagttc ttgcaaataa caaagaattt ttattatctg atactgttgg ttttgtaagt
     1201 aatctaccac atgacttagt aaaagcattt aggtcaacat tagaagaagc atgtgaggca
     1261 gacgtactgt tacatgttat tgatatttca aatccaagct ataaaagtca tattaaagtg
     1321 acagaagata ctttaaaaca aataggtgca gatggtatac ctatgataca tgtgtataat
     1381 aaaattgatt taatagatgt agaagtattg gatagaattt tagatagtat cgataaagaa
     1441 ggtatatttg tttcagttaa aaaagatata aatatagata aaatgataaa atgtatttgt
     1501 gatagcatat ttaaagatta tgtaagatgt aagttcttaa ttccatatga taaaggtcat
     1561 gtagtttctt attttaacga aaatacgagc attataaata cagaatacag agaagatgga
     1621 gctattttag atgtagaatg tagcaatata gaatataata agtataaaaa gtatgcttta
     1681 gagtaaattt tgaaaaactt attatagcct aaaatatatt taatttataa tttattataa
     1741 attgattgta aatatgattt tatgaaacgg tatagccata atgctatgcc gttttgccgt
     1801 ttataataaa aataaattta ttgacataat agtaactaat tactataata taaagtaatt
     1861 agttactatt taaaattatc aaaaaattaa aatctaagat aaagagaagt gtataataat
     1921 ggatgcagaa actttaatga aaaaatatat ggtagatgat gatagtagaa aacaagctat
     1981 atttgcaagt atatttgtaa tgcaaaataa acttcaaact acatgtgata aattagaccc
     2041 agaattaaca atgaaacaat ggttactttt agctattgcg gactctgtag atgaaactct
     2101 tacattaacc aaacttggag aattaatggg gtgttcaaga caaaatgtaa aaaaactagc
     2161 tattgcttta gaaaagaaag gttttataga aattgagcaa aatgaaaaag attcaagagc
     2221 tatctgtctt gtgacaaaag atagagtgca agagtattct aaaaaagtaa gaggtatgca
     2281 ggaaaaagta ttacagcttt tatttgaaga ttttacagag aaagaagtgg aacagttatt
     2341 ttttggaatt atgaaattaa gtataggaat tgaaaatgtg aaaaattatg tagaaaataa
     2401 tgacgttgga gaataagcaa gtatcaaatc aactttgtat gacatcagag aggggggtaa
     2461 tttatatgaa aaatgtagta gtgatttata agagtaagta tggttcaaca aaaaaatatg
     2521 ctaaatggct ttcagaatta ttgtcttgtg atatttttga aactaagaat attaatatag
     2581 aaaaggttat gaagtacgat acgattattt taggaggagg tctttatgct tgtaatatag
     2641 cgggaatttc tttcttaaaa aaaaattata aagaattgca gaaaaaaaat ttagtagtat
     2701 ttggcgtagg agctgctcca tatgatgatg aagtaataaa gaaattaaga gaagtaaatt
     2761 ttaaggatga attaaacaaa attccttgct tttattgtcg tggggcatgg gatgagacaa
     2821 aaatgtcttt tatagattat actctttgta gtttttttaa aaaatctata gctaaaaaag
     2881 aacgtcaagg tcttaaacca gcagaagcac ctttattgtc tggagaagca tttgattggt
     2941 gtaataaaga aaatttaact ccaatacttg attatataag agaactttaa gaggtatata
     3001 tttataatta tttattatct aaagttagat ttcatagaaa cttactagac attatttata
     3061 aaataatatt attaaagatg gataatttaa ttttttcaat aaggttataa ttttaaaaaa
     3121 tgtttatttt aaaataaact attttataag cttacttata cttaataagg ggcttttttt
     3181 attggaagat ttatgttata ttgagatgaa tttattatga tataaaaaat aatgttaggg
     3241 taaatttaaa tctttttcta aaaatgtatt agtataattc ttaaagaaag gatttttaac
     3301 aatggatata aaagagttag ttaaaatgca aagaaaatat tataatacag gtaaaacaag
     3361 agatatatcg tttcgtatag aacagttgaa gaaacttaag ttagttgtat cacaaaatga
     3421 agaaaaaata cttttagcac taaagaaaga tttaaataaa tcggattttg aaggttttat
     3481 gacagaagta ggcatgtttt atagtgaatt aaactttgct ataaagaata taagaaaatg
     3541 gagcaaaata aaaagagtta aatcaagtat ggttaatttt ccatctatat ccaaagttgt
     3601 tccacaacct tatggtgtta ctctcataat gtcaccttgg aattatccat ttcaattagc
     3661 acttatacca ttagtttggt cattatcagc agggaattgt gttatattaa aaccttctga
     3721 atattctgtg tcaacatcta gtgtagttaa agacatagtg gaagatactt tttcaaaaga
     3781 atatgttgca gttgttcaag gaagtcaaga agaaagtgaa aagttactat tggaaagatt
     3841 tgattatata ttttttacag gaagtactaa tgttggtaga ataatcatga aatcagcatc
     3901 agagcattta actcctatta ctttagaact tggaggaaaa agtccttgta tcattttaaa
     3961 agatgctaat atagacctta ctgccaaaag acttacttgg ggaaaactaa taaatgcagg
     4021 acaaacctgc gtggctccag attatgtttt agtgcatgaa gatagaaaaa atgagttaat
     4081 agagaaaata aaatattata ctaataagta ttttggagat aatccatgta ataatgagca
     4141 atttcctaaa atcataaatc agagacattt taatcggata ttatctctta ttgataaaga
     4201 taagatagtc tatggtggaa attataataa ggagacatta aagatagagc caactatagt
     4261 agacaatgtt aattgggatg ataatataat gaaggaagaa atatttgggc ctatatttcc
     4321 cattttaaca tataaagatt tggatgaagt aatacaaaaa attatacaaa tgccaaatcc
     4381 attggcactt tatattttta caaaaaataa gtacctagaa aataaacttt tagaaatgat
     4441 tccagcaggc ggatgttgta tcaatgatac agttactcat atagctacga attacttacc
     4501 ttttggtggt attggtgaaa gtggtatggg ctcatatcat ggaaaagctg gattcgatac
     4561 atttactcac tataagagtg tgttaaaaaa attaaatttg gatgtcccta ttagatatgc
     4621 tccatatgat aacaaattaa ttaaggttct taaaaagata atgtaggtta tattgtagaa
     4681 taataaatat aaataaaatt gagtatttgt attctgaata tattttattt ttaatttggt
     4741 atatttgtta taaaagtggt gattttgtga taaaatttaa ttatatagaa ataaggagga
     4801 aaaaatgaaa attaattgga atacaaaata cacaacaata gcaatttata catttataat
     4861 agctgctagt agtattatat tttatctagt atcatcacaa attgatgtat tttctaataa
     4921 tttagatgct atatttacaa cattacaacc ttttataata ggatttgcta ttgcatatct
     4981 tcttaatttt attttaaagt tttatgaaga cagaattttt ataaaaagtg agaaattaaa
     5041 aaaactaaaa caaagttcaa aaagaggctt gggtctttta ttaacatatg caacagctac
     5101 attgatactt tacttattta tgcatttcgt attgccacaa gtaattgaga gtattgttgg
     5161 actagcaaat gatataccta tgtatgtaaa caatgcaact aagcttattg ataaattaat
     5221 gactgattta aatcttgatg agcaatactt taatttggca gttgataagt ggaatgagtt
     5281 tgttacatat attataaagt ttgtaacaga tttaatccca atattaggaa gtatgttaaa
     5341 gaatgtagcc tctagtatat ggaatattgt actaggatta attgtttcag tatacttatt
     5401 aattgataaa gaaaaattct atggattaag caaaaaaata acttatgcag tatttacaga
     5461 aaaacaagct gccagaattt tagaattaac tcatagaagt aactatacat ttggaagatt
     5521 tttaggtggc aaaatattag attcattcat tataggtatt ctaacatttg taatacttac
     5581 attagttaaa atgccatata cattattaat atcagttata attggtatta caaatattat
     5641 ccctttcttt ggacctttat ttggagctat accatctacg ctaatagtga tgtttgtatc
     5701 tcctataaaa gctttctggt tattgttaat tatattaata atacaacaga tagatggaaa
     5761 tattatagga cctaaaatac ttggagattc aattggtata tctgcatttt ggattttgtt
     5821 ctccttattg gttgcaggaa aattattagg ttttattgga atggttatag gagttccaat
     5881 gtttgcagta atttattcta taattaagga tattgttgaa agtaaattgg acaaaaaggg
     5941 attaccgaca gatacttccg attatatgta gctaaaaaat attatgtata attaaaaata
     6001 tataaattaa gcaatattta aagcactgag aaagttaaac tcttggtgct ttttagatat
     6061 aaaattatta tagaagaggt gttttttgtg gcatttatag aatgtaaatt taaatctaaa
     6121 tatactggag gagaaactga tataattgta attttgcctg tagcaaatgg aaaagaactt
     6181 tttagtggta aagagatata tgattttgaa ggtaaattta aaacattata cttatttcat
     6241 ggtttagaag atgaccaaag ctcatggatt agatatacta atgtagagca ttatgctaaa
     6301 aataaaaata tagccctagt aataccaaga gtagaaacta gtttttatac cgatatggcg
     6361 tatggacacc aatattttac ttttgtaagc gaggaattac ctaaatttgt tagagctata
     6421 tttcctttat cagataaaag ggaagataac tttgtagctg gtatgtctat gggtggatat
     6481 ggagctttaa aattagcgct ttcaaaacca aaagagtttt cggcagttgc aagtttttct
     6541 ggttcgcctg atatgattca tgagttagaa aatcaacaaa tagaaaccaa tgcagacatt
     6601 ctatttcacg attttggtag accagaagac gctagaaata gtgagaatga tttactttac
     6661 atacttaaga accttaaaga aagaaatgaa gatattccta aaatttatca attttgtggt
     6721 gatagagatt ttttatataa aaataatcag atgtttaaaa aatatgcaga gtctctgggt
     6781 gtagatgttg aatatgaaga gtgtgtaggg gggcatgaat ggcgtctttg gaatttatgg
     6841 ataaagaaat ttatagatat aattggatag tacacttatg gtattaacag gtatactata
     6901 aaatatcttt aaatatgata aagactgaaa tcctaaaatc aaattatgat tttaaaattt
     6961 cagtctctaa gaatttaata aaattttatt aagttcttac acgagttatt attggagtaa
     7021 aattgtcaac tatatctata tagtatttac tcaattcctc taaaatctct tcgcataaat
     7081 ccgtactatg accaagatta ataagaaact gttttgtaaa atgctttatt acagcttgag
     7141 aagatatatc gtacttgtgt gaagtataaa ctctaattat ttcaggtttc atagcaagta
     7201 taccaataca agaaagtatt aattcatcat gttctataga ttctttatca ttaacatatc
     7261 ttttcatgac catttcggtt acacttcttt gatagcttaa aatagcttct tcataagcta
     7321 tatccaaata aaaatttcta tatgcttcgt tttttagaag gaaacaaagg tcagcattca
     7381 tagcaagaaa gaacatcatc atagtacctt cttcatggta gttatagatt aaagactgca
     7441 tttcatttct tatatcttca tatattatag ctcctatttc gcttttactt gagaagtaat
     7501 agcttattag acctaaattt atattagctc tttctgcaat ttgcctagtt gttgtcttat
     7561 ggtaaccttg ctcaaaaaat aattctctag cagcacttat aatactagct tttgtttctt
     7621 tgcccttttc tgattttgac atatttactg tgtatacctc tcttttcaat ctttttttga
     7681 aaatttgcta actataaata ttgtaataga accacctatt ataggaacca aaattctgtc
     7741 aaatacagta agaataccaa tcatatttaa taatgccaat ataacactta ctataacagc
     7801 atagatagct cctttttttg tagcaccttt ccagcaaaga ccaattacaa atggtgcaaa
     7861 tattacacct gtacataatg gagccggcca aaacaataat tctaataaac tatcaaattt
     7921 aagtgctatg attgcaccta ttatagctgt caaagctgat gcaatttgag aatactttag
     7981 agtatttttt aaatcattaa attctatatt aggatgtaat aatttgttat aaatatctct
     8041 tgatataata gcactcattg aggtcattaa tgaatcggca gtagacatta tggcagccaa
     8101 tatagcagct aagaataata cagatattaa aggtggcaaa gtagtcgata tcatttgagg
     8161 taaaacctga acagatgata tgtttggaaa taaactacca ccaatagctc caattattcc
     8221 tatagggaaa gcaagaaata atagtataaa tcctgcaatt acactacttt taactgcatt
     8281 tttagcatta tcagcacatt gatatcttaa aaaactttca taagaaaata ttgagcctaa
     8341 aactaatggt aaaactgtat acataaaatc actaatcgat ttatttcctg gaaagaatgg
     8401 ttcttttacc attgattgta acataagtaa agggttgtcg ccaactaatt ttaagcttat
     8461 ataagctact attggcaaaa acactataca aatagcaagt tgaataaatg ctgatactgc
     8521 aactccccac attcctgatg tataagtata tataatgata actataactc ctataattac
     8581 agctatatca taaggaatac caaatgcagt agatacagaa ccaaaagaaa tcaattgact
     8641 acccataata gctagtatag atattggtgt tacaagactt tgataagctc ttaaaaatac
     8701 actatgacca tatctagttt caatataatc agcaggtgtt atatcacaag ataagcttct
     8761 taattttcct gcgaaaaatg catttataaa gcaagctaaa gctgcaccta tagtagaata
     8821 cattccaacc caaagtcctc tttcagctcc ccattgaact ccaccaacta agcaccctcc
     8881 tccaaaagat gtagcagcaa tggttgcagc tagtataggc aaaggcagat ttctacctgc
     8941 gattaggaaa tcggatgctg ttttaacttt ttttgaaaaa taaaaaccaa tccatatgta
     9001 tattgcacac gtaacaatta aaagtaacat agtcttttct cctttataaa atattttaat
     9061 aaaatatata aaatatattt aaaatatatt ttatataaaa gtagtacgat atttgtttta
     9121 ttggttttag attaatatag ctataataat ttatgatatt agatggaaat tacgtaaaaa
     9181 tagaaaattg aaaattctga aatttttgca tattgatatt tatctcatag attctttttt
     9241 gtaattgtaa cacgctttta tttttaaatc aatagtacat gtataaaaat aaaaggaatt
     9301 taaataagaa aaagatattt ttaatatctg gatgtagtat agaaatatct tgaataaatt
     9361 attcttgaat aaaattataa aaaattaaaa ttactagaaa tatgataaaa taatttaaaa
     9421 tacgcatttc aatgacattt caaaacaaga aaataataaa aaacaaacct aaattaagtc
     9481 taaatagctt tttagttaat tttagtagta aaaaataaaa cttaaaaagt gtttgacaat
     9541 tatgaatttt gagaatataa ttaaattaaa attatacaca tataaaaata tgctctgaat
     9601 caagaatgag atatttaaga ttcaaaatat atattattat acgtgaataa taaaaagtaa
     9661 gaaaatttta taagggaggg gtagatgtga gtagtcaaga aagcaaacca aaaggaaatc
     9721 ttatatcaaa ttttagagat gatatgagag accctaagaa aagagcaata tacacatatt
     9781 caagttctat aaacttagcg tacaatttta taggttactt tgtatcaact gttacaaata
     9841 tttttttaac tgatgtggca aaacttggtg taattatggc aggtggtatg caaattatac
     9901 aatctttcat aaaaattgct gtagctccta taacaggtac agtatttgac aaacaaccat
     9961 tcaaaaaagg aaagtattat ccatggctta gatatgcacc agcagcgtta gcattaacat
    10021 atggaatatt tttcatagtt ccattaatga aaataagtcc agcattactt ttacctttga
    10081 tgacagcttt attattaata gcatcttgtg ctcagcaagt agttttcact ataatttatg
    10141 ctatttaccc tgtagttgct aagacaccta gagaccgagt tataggctca actactacga
    10201 atatatttaa agaagttggt aaattcttag taggtttttc atatccgtta ttattagttt
    10261 tatttgcaga tgtattaggt ggagaaggaa tgggttattt aggtacctac ttattctttg
    10321 cagcaggatg ccttttagta ttttggtttt cttcaacaga gataataaaa tctggagcag
    10381 aagaagaagt tcttcaaaaa gaagagaagc caaagattaa agcaagtgaa atggcaaaag
    10441 ctttattcac taatgtacca cttatgatgg cattttgttt agaatttctt atatgtataa
    10501 gatctatagg attaggacct ttggctccat attattttaa atatgtaata gaagatgaac
    10561 gtggattagc agtattttta tcaatcatgc ctttggtaag tgtagcattc atgtttttcg
    10621 caccagtgtt tataaaaatc tgtagagagc aaaaactagc ttcaataatt tctttttcta
    10681 tatgtgcact atgccactta ttggttgcat ggactccttg ggggaaaact actttaggag
    10741 taactatgtt gctggcaatt ggtggaggtt tttcaaatgt agtatcaata ataaatctta
    10801 atttctttgc cggttcttgt gattatgggc attggaaatc aggaaaagac ttacctggct
    10861 taagtatgtc actatatcca gttgcaatac aagtaggagt attacttgca actactataa
    10921 gaacagtttt aatgaactca atgggatatc aagctgatat ggtagtcaca gaagcagtta
    10981 aatcaggttt tataaatatg atttcttatt ctatggcaat acctttaata atagctgttg
    11041 ttatagcaat actatatcca gtaagtgaca agaaattaaa ccaaataaga gaagagttaa
    11101 atcaaagaaa tgcttagcta aaagaaagtt aagtagatgg ttaatttaag ctattaaagt
    11161 aagtagacgc aatagcgttt atataaatga aaatacatat acagaggagg cttttaaaaa
    11221 tgatagaaaa attattgaga aataccgtaa aagaattaca tcaatatgtt ccaggtgaac
    11281 cagtagaaaa agttaaggaa aaatatggtg taaaagaaat aataaaatta gcttcaaatg
    11341 aaaatcctct aggaccatca ccaaaagcaa tagaagctat gattgaaatg ctaaaacaag
    11401 gtcaacttta tccagagcca gaagctaacg aacttagaag aaaattagct gaaaagttag
    11461 atttaaaacc agaaaatttt attgttgcta atggtgcgga taacgttatc actctaatag
    11521 gtgaggcttt tataaataga ggagatgaag ttatatattg taacccaaca tttccatcat
    11581 atagaactgc aactataaaa aatgaaggga taccagtaga agtaccttta acagaagatt
    11641 ataagtatga tttacaaggt atattagata agattacaga taaaacaaaa ttaatatgtg
    11701 tatgtaaccc taataatcca acaggaacaa ttgtggatga taaagagtta gaagaatttt
    11761 taaagaaagt ccctgaaaat attataacta tattggatga agcatatata gaatttttaa
    11821 cagttcctaa ttatgtggat ggacttaagt atgtaaggga aaattataac gttatagtaa
    11881 caagaacttt ctctaaaata tatggtcttg cagggcttag agtaggatat ggtattgcta
    11941 aagatgagat aataagaact ttatttacag taaaagagcc tttctctgca aatcgtgttg
    12001 ctataagtgg agcaacagca gcacttgatg atgaagagtt tataaaagaa acatatgaat
    12061 taaatagagt tggaatggct tactttaaag aagagtttac aaaaatggga tttgatgttg
    12121 tagattcaca atcaaatttc ctttatgtag atatgaaaac agatatacct aagttatttg
    12181 aagacttgaa aaaaagaggg tttgtaataa gaccaagtgc tacacatgca cgtgtaagta
    12241 ttggaactat ggaagaaaat aagaaatttg tagcagtttt aaaggaaata ttaaatatta
    12301 aaggagagcc aagcattgga taatagatag aaatattatg aaacggggtg tagatatgaa
    12361 cttaaaaata aacgcagaga gatgtaaaag ttgtgaatac tgcgttatat cttgtaaaaa
    12421 aggagcatta aaaatatcaa gtaagataaa taaagaaggt tatgctcatg tagaagttga
    12481 tgagagtaaa tgcatacttt gtggaatttg ctatcaggtg tgtccagata atgtttttga
    12541 aataattaaa gaagaagcat gtcaagaggc ttagaaggag ttgggataat atgaaaaaga
    12601 tgtggaaggg gaaccacgcc attgcagaag cagctctaag aggaggttgt gaattttatg
    12661 caggatatcc aattacacca caaacagagg taatggaatt tttatcacat agaatgtctg
    12721 aacttggaag aacttttata cagtccgaaa atgagatggc tgctatatat atggtatatg
    12781 gagcatatgc aagtggaatg aggtctatga cgagttcttc aggaccagga atatctttaa
    12841 aacaagaagg gatttcttac ttatgtgcaa atcattaccc ttgtgtaatc gtaaatgtac
    12901 agagatgggg gcctggtctt ggctcattgg actcagcaca gacagactat ctaagagata
    12961 ctagaggggg aggaaatgga gattatcatt tgatagttta tgcaccaaac agtattcaag
    13021 agactgtaga tttgatgtat aactcatttg atgtagcgga gaagtacaga gtgcctgtcg
    13081 aaattttgac agaagcagct ttaggtcaaa tgatggaacc agtagaattt ccagagttta
    13141 agaagagaga aggagattta ggttggactt atgatggaag taatagagac catgcaaagg
    13201 ttgcagataa ccaaaagcca actttttgta tggagaaacg tatgagaata actgaaaatg
    13261 aacaacaatg ggaagattat caagtagaag atgcagaata tgtgtttgta gcgttcggta
    13321 taccatcaag aacaactatg aatgctgtta gaagacttag agaacaaggt gaaaaagttg
    13381 gaataataag accaataaca gtatggcctt tcccatataa agcatttgaa aaggtaagta
    13441 aagatgtaaa aggatttatc tcagtagaat caacagacac aggtcaatta gtagaagatg
    13501 ttgctttagc ctcaaagaaa gtatgtaaag aaaatgtacc tgtgtatggt ttatttagtg
    13561 gaaatcatat accaaaaaca ttgcaagtaa tggacactta tagcaaaata aaatctggcg
    13621 aaatcaagga ggtgttctaa tatggctaca gaaaaattaa cacctagcgt tgtttcaata
    13681 ccaaacaagt tttgcccagg ttgtggtcat ggaatagtaa atcgtataat agcagaggta
    13741 atagaagaac atggatatga aaaaaatcat gtattaacat taggagttgg ttgtgtctgc
    13801 aatatgaatt ttagctggaa tggtgataag atgcaaactg cgcatggtag agcttcatct
    13861 acagctatag gagttaaagt agcacttcca gatacattag taatgactta ccaaggtgat
    13921 ggagatgctt atgttatagg tctttctgaa actttaaata cagcatatag aaatcataat
    13981 gtgactgtat ttgtaataaa caataataat tttgcaatga ctggtggaca aatgtcatgg
    14041 accactatgc cgggtcaagt cacaacaaca agtgtaaatg gaagagatat aaagactact
    14101 ggtagtccac tgaaagttcc tgagatggtg gcaaacttct ttgatgtagc atatgtagca
    14161 agaggttcag ttcatagccc aaaggaaata attaatctaa aaaaatatat aaaaaatgca
    14221 atagaagctc aattaaatgg agagggatat tccttagttg aaatattagc accttgccca
    14281 actaactggg gtgtatcact agagaaatct atcaaatgga tggaagaaga aatagtgcca
    14341 tattatgctc ttggcgaatt taagcaaagg gatggtgaat agttatggaa aaagagctag
    14401 tatttgcagg gtttggtggt caaggagttt taactcttgg tctgattgta gctgagtcag
    14461 cacttgaatt ggggaaacaa gtaacttgga tgcctgcata tggtccaact atgagaggtg
    14521 gaaaagctta tagtgtagta aagttttctg atgagagtat aggtgggcct gatatggaag
    14581 aaatagatgt tttagtagca atgaataaac catctttaga ttatataaat ttagttaaag
    14641 aaggtggaac agtagttatt aatacatctg caatagatga gaatgtaaca ttaagagaag
    14701 atataagtgt agttaaaata aattgtcagg aattagctca aaaagtaaac aatccaaaag
    14761 cagcaaatat agtagtactt ggagcattaa ttgctaaaac tgggttattt gaaaaagaat
    14821 tagctttaaa aactatgtgt gatttctttg aggaaaaagg aaaaggaaag tttaatgttc
    14881 aaaatgaagc agcattcatg gaaggctata ataacgccat ttgataaatt acccttatct
    14941 taagtgattt atctcaagat ttaataatct ttagtgccaa gagaaacttc atcttgagat
    15001 aaaattcact taaaatcaca actataaaca tataggagcg tgaatttatg agtttggaaa
    15061 aacttattag accaaaaagt attgctatag taggagtgac tgataaactt ggttttggaa
    15121 gaagtgcagc acttagtata gtaaaaagta aggaaacaga tagagtatat tatgttaatc
    15181 ccaaaagaga agaattgttt gggagaaaat gttataagac gatacaagaa gttccagaag
    15241 tagtagactg tgtagtagta tgtacgccta gaaatgtagt tccatctgta ttaaaagatt
    15301 ctggagagtt aggaacaaag gcagcagtgg tatatgctag tggatttgca gaggaaggta
    15361 cagaggaagg tacagattta gaaaatcaac ttatagaaat atcaaataca tacgatatga
    15421 aaatattggg tccaaactgc atggggttgc taaattgtat agataaggtt aatctatggg
    15481 caggaggttc taaatgggat ttagatacta aaaaacctgg tataggaatt gtaggtcaaa
    15541 gtggatttat aactgctgaa attgtttcaa gtgattattt taatatatct tatggttttt
    15601 caacaggaaa tggaaatata gttacactag aagatgcagt agatttcctt gtagatgatg
    15661 attatgcatc agtaatagca atttaccttg aaggtttaaa aaatcctcaa aaatttatag
    15721 atgctttaaa aagggcagca caaaaaagaa agccagtaat aatattgaaa tcaggaaggt
    15781 cagaaaaagg tgctatttct gctgcttctc atacaggaaa tctagctggt tcgagtaaag
    15841 cttttgaaag tatttttgaa aaatatggag taatttctgt ggaaaattta gaacagttta
    15901 tgtgtttagc acaagctttt agtgttttag atggtaattt acctgcaaat tctaattttg
    15961 cagcaataaa cttctcagga ggagaaaata ctatttgtgc agatttagca gaagaaaatg
    16021 gtgtagaact tgcagaaata tcttctgaaa ctaaagaaga aatgaaaaaa tatcttccag
    16081 gatttgcaac acctaaaaat ccactagatg ctacaacagc attattccat gaaaaggata
    16141 tgatagtagg tttattacat acctttgaaa aggatgatag tgttggattt actatggtag
    16201 gtgcaaatat aagagatgaa gaaaatgaaa tgcatgaaac cctttgtaaa gctgtaagtg
    16261 aagctagaga acaaggattg aaaaaacctg tgtttgcagt tcctacactt gaaggaaata
    16321 gatatttaga ttataggact agattagaag ataatcaagt gcctataatg tcatcagttg
    16381 gaactacatt tacttgtttt aataaaatgg ctaagtttat agattatgat tattcaaaaa
    16441 gaactttaga atttaaagct gttaagaaaa gagagtcaaa taatgtagta gcattatcag
    16501 aattagatag taagattgag atgaaaaaat atggagtacc agttccagga caaggtaatg
    16561 caaaaagtat tgatgaatta gatgaaatct taaaatatat taagtatcct gttgttttaa
    16621 aaataaattc ttctgaaata ttgcacaaat ctgatgttgg aggagttaaa ataggaatta
    16681 agaatagaga tgaggcagta gatgcatata atgagatttt aactaatgta aaaaaagcaa
    16741 aaccagatgc taatattgat ggtatattag ttcaagaaat ggtagaaagt ggtatagaaa
    16801 ttattattgg tataactaat gatgaccaat ttggaccaat gttattagtc ggtttgggag
    16861 gagtatttgt agaggtattt aaagatacta cattatatcc attacctata aatcatgatg
    16921 aagctattat gatgcttaaa aaactaaaat catttaagct tttaaatggc tatagaggaa
    16981 gtgagccttg cgatattgat gctcttgcag atatgatggt caaattagga aaatatgctt
    17041 atgaaaataa ggatgaagtc aaggaaatag acttaaatcc agtgtttgta tatcctaaag
    17101 gaaaaggcgt atgtgcagta gatgccttaa tagttaaata taaatagttt ataagttttg
    17161 gtattcaacc ataattaaag caccgactga aaatcacatt ttgtaagtta gatagtgtga
    17221 ttttcagtca ccccaaattt aatttaaaaa tattttaaaa tgaaagtata gttttaagtt
    17281 tcattgtgaa atagcactgt ataaacaata aaatactacg tataaaacga ataataaaag
    17341 gtgttttaat gataagaatc aatcttgatt ttcattaaaa caccttcttt attatattaa
    17401 aaatttttaa acgttatatt gtcacaggtg ggtttgttgg agctgcatat gtacgattag
    17461 caaattcttg gtcaacaaag aatagaccac cctctccagc aagtttaaca cgttttatat
    17521 tgtcttcaca atttgtttct tcttctgctt gttcagatat aaaccaaagt aagaattgag
    17581 aagttctaaa gtctgattca gagtttgcta cagctgctaa gttgtttatt aaagctgtaa
    17641 cctttttttc atgagctaac gtacgctcaa gaatatccat tgcagaagta aagtctgaat
    17701 ctggcattgg gatagcatca agctgaacct ttcctcctac attatgtaag tatttgtaaa
    17761 aaaacatagc gtggtctgtc tcttctttat attgaacata aaaccaatta gaaaatcctt
    17821 taagtccttc tgcttcaagg taagaagaca tagaaagata aagatacgca gaatataatt
    17881 catggttaat ctgctcatta agtaattttt ccattttagc tgaaatcatt tttatacctc
    17941 caaattttaa atgctcttat aaaatataat aatattaaat ggaaaaatat tcaataaaag
    18001 tgtttaaata ttttacatat ttaataaaaa tttatactac cattaaaaaa attataactt
    18061 acaatggcta tagagccaat taatggtgca tttgctccaa aatttgaatg ccttacactt
    18121 atttttttat atttagaaaa acttgctgaa gcagtcaatt tttttaataa tgtattttct
    18181 ataaatgtac caggtatatt aaagtcatag cctattatta tagaactaca atcaatcaat
    18241 gtaagtgtat taactaatgc atatgatacg tatgtacaaa attcatcaag caaaaacatg
    18301 gcaagactat ctttattatt tgcctcatct attaacttga ctaaagaaaa atctttacag
    18361 ttaattaatg gggagttagg ataaatatgg ctcaatgatt caattctttt aattagatta
    18421 ctgacacttg tataataatc taaacatcca ttgttaccac aactgcacaa tggtccacta
    18481 aaattaattg atgtatgtcc tatttctcca ctttgtccta ggttgccagt atgaagttta
    18541 ttttctagaa ctagaccagc tccaatacca ttcattatgt gtaggtatat ataatttgat
    18601 atatttttac ctaaaccata cattttttct gctaatgcac ccgaattagc atcatttatc
    18661 aaaaatattg gcaaatcaga catttctttt ataaaatcta ctatatttag gtttgataca
    18721 tttccaaagt ctgggggatt tagtatggta ccatttatat catctactgg acctattgaa
    18781 gaaataccaa ttccaattat atctctcttg ttgattttca ttattttagt aaacattctt
    18841 tttattatat cttttaaaac atcatttgat agaaatttag ggtaagtttc agaaagttgt
    18901 tttacaatat taccttttaa atctgaaata attaccttac atatatttct tcttattagg
    18961 attccacaaa tacaaggcga tatattagaa atatctaata aaatgggttt acgacctgat
    19021 gaatgtgcat ttaaagttga tgactctatt tccctaatca tattttcatt aataagttca
    19081 gtaactagat ttgataaagt cattttagta agtcctgtag acttagctaa atcaactctg
    19141 gacataggtg tatttgtaga aagtaatttc aatattatta acttattttt aatttttaca
    19201 tctttgatgt tagaaccttg tttgttactc atcataaatc tccttaaata aagttaagtg
    19261 ttttatttat tttcaagtat actatcacct tataatagag taacattttt ttacttgaaa
    19321 atatcattaa ttagaatata tcacattata tatcataaaa tatataaaaa aatgttagaa
    19381 ttaaattaaa agtgaaaagt agattgatat ataaatagta aatacttaat taaaaaaaga
    19441 taatgatagc aataattatt gttaccaaga atctactact tcaagtgtta ccttaggtat
    19501 ttaagttgat agtggcttgc acgtaataaa cttgatgtaa tatatattct taataatatc
    19561 gataaaagat ttacttaaaa ataatataga ttatgtaaac atataatcta tttattgtat
    19621 acaataaaat ttcattttgt aaaacagtga attaaatatg taatatagat atcgattttt
    19681 attacaaatt gttactaaat ataggtacat tagaacaaaa atctagtaaa ttgtaactaa
    19741 aatgtaaatt tttcctttaa tctatacaat attatggaaa ctttttgtaa tttatgatat
    19801 aataacaaat atataattat taaattataa taaatgacta tagcgtagat gtaatactat
    19861 gttatagtca tttttgaatt aaacttgata tatcaagggg gaagaatatg agaacaatta
    19921 gaagagtttt agcattaggt ttaacattag ctatatttct aataaatgta cctaatgtag
    19981 atgcattaac atcagataca attaaaggta acaatatata tgagacagct ggattaatag
    20041 cagataaaaa gagttatgat acagcaatta tggtaaatat ggataattct atagcagatg
    20101 gtctttcagc aagtggtctt gcaggtgctg ttgatgctcc aattttgctt gcacaaaaaa
    20161 ataagatacc aaatgaaaca aaacaaagat taaaaaatgt taaaaagata tacataatag
    20221 gtaaagaatt atcaataagt aagtcagtag aaactgaact aaaaaacaca ggggcacagg
    20281 taactagatt gggtggagat gacagaataa agactagtta tagtgttgct aaagaggtaa
    20341 atggtatcaa aaaagttgat gaagtgatat taactaatgc atataaagga gaagcagata
    20401 caataagtgc tgcacccgta tcagtaagag atatagctcc tatagtactt acagatggaa
    20461 agagtgtgcc tttttcaaca agcaatgtaa aaacatatgc agtaggtggg agtatatcaa
    20521 tgagcactag tttagttaat aaaactaatg ctaaaagact tggtggttca gatagatatg
    20581 atacaaataa gaaagttata aaagagtttt attcagatgc atcagaattt tatttgagtg
    20641 atggatatga tttagtaaat gcacttacag gttctacaat tgctaaggaa aatccaattg
    20701 tattggtgtc agaaagtagt gataagtcta tattagcagg agcagataag attactagat
    20761 taggttcaat aagtgacagt gtgtataata agtgtgtttc tgctgcacaa aataatggcg
    20821 attcgtctac aaaaggtgag tcacctatga aaaatgagac aagcatatta ggtcagccaa
    20881 cagctagttt agaagcgtgc ttaaaatggg caaaatctaa aaaagctaat gatttattta
    20941 tagagttaat accaatatta tatgatactg ctgttcagga aggtgttaat cctgttttgg
    21001 cagtagctca atctgcaaaa gaaactggtt tttgtaattt tggtggagta ttagatgcat
    21061 catttaagaa tccttgtgga cttaaaactt ctgtaggtgg ttctgatact gataagaatg
    21121 cccattcaag atttgatact tgggaagaag gaatattagc tcaaattcaa catttatgct
    21181 tatatgcagg acaagatggt tacccacttt caaatccagt agaccctaga catgaaaaat
    21241 ctttatttgg taaggctaaa acagttgaaa gtttatctaa taattgggct ggaggtcaat
    21301 atggacaaga tttagtaaga atgatgggag aaattgaggc aacaaaataa ttgaagatta
    21361 tcaaatatcc aataaataag gattgattat tatgaaaaag agtaatattt ttagtatcat
    21421 atttcctaca gtcataatgg tgctaatgtt tttaactttt gctacagata tatttaatat
    21481 tccagatatt caatctaaaa gtatttttgt tgtgggaatg gttttgattt ttccaatttc
    21541 ttttttgata caagggataa tttgtgtatt aaataagact aattggattt tatctcttat
    21601 tgtgtcttta gtaacttata tagtattaat gtatatattt ttaaatgatt ctgcatatat
    21661 atatgtttta ctttatacag ctttttatat gattggacat ataacagcta aactctatta
    21721 caaaattaag acttttaaaa attaaattga agtatataaa agtaacatta agagaagtat
    21781 ccttaatgat tttctaaaat cagaaatagg tgcttctctt ttttgtaaaa ataaaagtat
    21841 gtaaataaaa tttaaccatt ataattttct tttaacaaat gtatacaata aacttgttgt
    21901 ataattaaga tagataaaat aaagggaggg ataatatgaa tttaatagat aatcatattc
    21961 atactaattt ttcaagtgat ggaaaggatt ccatggaaga tacaataaaa aaagctataa
    22021 gtattggtgt tagatatttg acttttacag accatttaga acatgatgaa gatagaggat
    22081 tttgcataaa ttataatgac tatgttccag tatttaataa gtttaaagaa aaatataaaa
    22141 aggacataga gttattacta ggtgttgaag taggttacag aaaacatcta aaaaatgaaa
    22201 tagaagaaat aataaattct aatccttttg attttgtatt gtgctcaact catacaattg
    22261 acaatgtacc tgttccatca aaggagtatt ttaaaggtct tagcaaagaa gatgcgtatt
    22321 ataaatattt taatagcata cttgaaacta atcgtgaatt tggagattac aatatatatg
    22381 gtcatttgga ttatatatct aggtatggaa tatattcaga taatagagtt atatacaatg
    22441 actttaaaga tgttattgat gaggtcttaa agtcaataat caataatggg agtggtatag
    22501 agctaaatac ttctggttat agatatggat taaatgctat acatccaaat gaagatattc
    22561 taaaaagata taaagaactt ggaggattta tagttactgt aggttctgat tctcataggg
    22621 tagaagatat atgtaaagat tttgatgtgg cctatgatat gcttaagtat cttgacttta
    22681 aatatgtatc tttatttaaa gaaagagaaa cttattttgt aaatatagaa aaagttaaat
    22741 ctaacaatat agcttagagt gtgttttgaa gtaaattaat ggatagttaa aaagttaata
    22801 gttataatat tgtatcctct agaaaaatac tagaggtttt tattttgcta aaataactaa
    22861 atagaattaa atttaaatag tatagtttat tttaaattga atagtttatt gttgatatat
    22921 tttactatta tatattttta ttgtgatata atagtaaaat atattaacct atctttagat
    22981 tatataaatt attataaagg agggaaattt taaaatgtct aataaaaata aagaaaatat
    23041 aactttaagt aatcaaatca aaggaacaat tcaaaatagt ttaacaaaag aagctatatt
    23101 acatatacca atgagcaatt atgcctatgg ttatgataga gaaacactac atataagact
    23161 tagaactaaa aaaaatgaag cgaaaagagt aattttacga ataggagacc aatatgtgtg
    23221 ggataaagga ggtgcaggag gaggaaattt aaatgcatct ggagttggtt ggtctggtgg
    23281 aacaaatata gtaatgagta aagaagtaga aactgaatta tttgactatt ggatagctaa
    23341 gtgtaagcct ttaaataaac gctcacgata tggctttata atagaaggtc aagaggaaaa
    23401 acttttattt acagaaaaaa gaataataga gttgggaaat gaaaatgatg aaaaggaatt
    23461 atgtgaaata ggtgattttt ttggatatcc atatttaaat tatatagata tacctaaagt
    23521 gccaaattgg gtgaaagata ctgtttggta tcagatattt ccagatagat ttgcaaatgg
    23581 tgacccgtct ataaacccag aaggagtaga taaatgggga gctattccaa ccagagataa
    23641 ttttacaggt ggagatttac aaggtgtgat agaacactta gattatttga gtgatttggg
    23701 aataaacgga atttactttt gccctattac aattggaaaa accaatcata gatatgatac
    23761 ggtagattat atggaggtag accctacatt aggagataaa gagactttaa aaaaactaat
    23821 agaagaagca cataagagaa atataaaaat aatgttggat gctgttttta atcatatagg
    23881 atattattct aaacagtggc aagatgtagt tcaaaataag gaaaattctc gatataaaaa
    23941 ctggttttat ataaaagata tgagtaaaat tgatactcca atagaacaaa tagatgaaaa
    24001 aaatatacct tatgaaactt ttgggtgtga aaaatatatg cctaaactta atacagaaaa
    24061 ttcagaagta ataaaatatt tattggatgt aggcaagtac tggatacagg aatttgatat
    24121 agatgcgtgg agattagatg tttcaaatga agtagaccat gttttttgga gaaagtttag
    24181 agaagaagtc aaaaaagtaa aaccagacat ttatatattg ggagaaattt ggcatggtag
    24241 tttaccatgg ctaatgggtg accaatttga ttcagttatg aattacttga tgtcagaagc
    24301 catgaaaaaa ttcttttgta cagatgagat aaacgccgaa gaatttaagt atatgataaa
    24361 tgatgtaatg gtaagttatc caatacaagt tagtgaagtt atttttaatt tacttggaag
    24421 tcacgatact acaagaatat tgacttatgc taatggaaat attgatagat ttaaacttgc
    24481 atatatgttt atgtttgtac aaacaggatg tccttgtata tactatggtg atgaaatcgg
    24541 aatggaagga gaattaagtt caatatctga aggtcaaaga aaatgtatgg aatggaatga
    24601 agaaaaatgg aataaggata tatttgattt tatgaagaag attattagac ttcgtaaaga
    24661 aaataaagaa cttaggtcta tatcaaatga atgggtgtta gcagataagg aaaatggaac
    24721 gattatattg aaaaaagaat ctatttctat aataataaat aattcatcta aaaatataat
    24781 tttgacgtta ccagattatt tagcaaataa aaaagtaaaa gatttatatg aagaagaaat
    24841 agttgattta aaagaagaac taatgttaga gaaatacaag ttcattattt taaaataata
    24901 caaaaaagta tttattttag atttcatgtt aaattattat acagtttaaa caagtcttta
    24961 taaacgataa aaaaatatgg tctacaagtg agtgaattga aagtagattt taaattaaag
    25021 actgagttag agtagataat tttataaata atatcttaaa tacaagatag aaaataaatt
    25081 gattattagt ctaaaaattt cttgtagaaa gaggaaataa gaatgattga agcatttata
    25141 tttgatttag atggtgtaat tacagatact gcatattatc actatatggc ttggagaaaa
    25201 ctagctcata aagttgggat agatatagac acaaaattta atgaatcttt aaaaggcata
    25261 agtagaatgg agtcattgga caggatatta gaatttggaa ataagaaata ttcattttca
    25321 gaagaagaaa aagtgagaat ggctgaagaa aaaaataatt actatgtatc attgatagat
    25381 gagataactt caaatgatat tttgccaggt atagaaagct tgttaattga tgtaaaatct
    25441 aataatataa agataggtct atcttctgca agtaagaatg caataaatgt attaaatcat
    25501 ttgggtataa gtgacaaatt tgattttata gctgatgcag gaaaatgtaa aaacaataaa
    25561 ccacatccag agatatttct tatgtcagcg aaagggctta atgtaaatcc acaaaattgt
    25621 atagggatag aggatgcaag tgcaggtata gacgctataa actcagctaa tatgttttct
    25681 gttggtgttg gaaattatga aaacttaaaa aaagcaaatt tagttgtaga ttcaacaaat
    25741 caattaaagt ttgaatatat acaagaaaag tataatgagt atatagttag gagaattata
    25801 tgaaatgttt atttagtaat gtagatgagt ggaagattat acaagataag attgaaatca
    25861 aagaaaatag attagcagag tccataatga gtataggcaa tggatatatg ggtatgagag
    25921 gaaactatga ggaaaattat agtggagata cacacaaggg gtcttatata gctggagtat
    25981 ggtttccaga taaaactcgt gttggttggt ggaaaaatgg atatccagaa tactttggta
    26041 aaattcctaa ttcagtcaac tatataggtg taagaatttt catagatgat gtagaattag
    26101 atttagcaaa atgtaaagta gaagattttc atagagaatt agatatgaaa aatggtattt
    26161 taaatcgtag gtttattgta aatataaatg ataaaaaatt tgaagttagg gttactaggt
    26221 ttttaagtat atctgttaag gaacttgcag taattaaata cagtataaaa tcattaaatt
    26281 ctaatactaa aataaaattt gtaccatatt tagattcaaa tataaaaaat gaagattcaa
    26341 actatgagga aaagttttgg aatggaattt cttcaagttc tttagaatat aaagggagta
    26401 ttctttctcg aacaaaggag aatgcattta atacaccagt attcactgtg ggttcaatga
    26461 tgtatattaa gacaaatggt gatgtagaag ctgtatctca tgagagtgat tataattact
    26521 gtgaaaattc gataacaatg gatgttttaa aaaatgaggt tgcaagtata gaaaaatatg
    26581 tatctataac ctcaactaga gattataagg aaagtgagct attaagaaaa tgtgaagaca
    26641 ttttaaatag agaactatct aaaagttatg atgatatatt aaatgaacat ataaagttat
    26701 ggaataaaag atgggaaagt gcagatgtaa aaataaatgg agataaaagt agccaacaag
    26761 gtataagata taatttattc caactatttt caacatatta tggagaagat tcgcgattaa
    26821 atataggtcc aaaaggattt actggtgaaa agtatggagg agctacttat tgggatacag
    26881 aagcgttttg tgttccagta tatctaggtg tagcagataa ggaggtaact agaaatcttt
    26941 tagaatatag gtacaatcag ttagaacagg caaaagataa tgcaaaaaaa ctaggtctta
    27001 aaggtgcttt atatccaatg gtaacatttg atggagtaga atgtcataat gaatgggaga
    27061 taacatttga ggaaatccac cgaaatggaa gtatagtata tgcaatatat aactatacaa
    27121 attatacagg tgactataaa tatataaaag aaaaaggaat agatgtaata atagaaatag
    27181 ctagattttg ggcaagtaga gttcatttgt ctacaaaaaa agatttgtat atgatacatg
    27241 gagtaacagg tccaaacgag tatgaaaaca atatcaataa taattggtat actaattata
    27301 tagctaaatg gtgtttagat tatgctgtag aaaatatctt acgattagag aaagagtgta
    27361 atgaatgtat tgacagaaat aatgtgacta gggaagaagt tgagttttgg aaaataatat
    27421 caaataaaat gtatctaccg tatgatgagg aactacaaat aataattcaa aatgataatt
    27481 ttttagataa agaatttgta gaagtaaagg atttaccaaa agaaaatttt cctcttaatc
    27541 aaaattggtc ttgggataag attcttaggt cgtgttttat aaaacaagca gatgtattac
    27601 agggaattta ctattttgga aatagattta ctaaagaaga aaaaaagaga aattttgact
    27661 tctatgaaaa atatactgtc catgaatctt ctttatcttc tagtatttat tctattattg
    27721 cctcagaaat agataaccta gaaaaggctt atgaattata ttcaagaaca gctaggcttg
    27781 atttagataa ttacaataat gatacaaatg atggactgca cataacttca atgtctggtt
    27841 catggctttc cattgtacat ggatttgcag gcatgagaac atggaatgaa actctatctt
    27901 ttgaccctaa gttgccaaaa gagtggaaaa attattcttt caatataaat tatagagata
    27961 atattattaa tgtagatgta tgtagtgatt taattaaaat agaaaattta aaaggtaaac
    28021 caataaaaat tattgtatat gggaaaaaat atatattaga aaaatgtata aaaattgata
    28081 aatagattta ataatatttt tattatataa atagttaaaa taagcttatc taattattta
    28141 tttattttaa ctgttttgtg tgatagaaaa ctatatatta taacaatagt agtgctttta
    28201 attaaatata tttcataaat cttcataaaa tcttcaaaat ttcgtaaaga atatgtcaca
    28261 aaagtaaggt atattatatt cagcagatag tataagggag gacaatattt atgaagaata
    28321 aaaaattcat tgttataata ctgataatat caattttaat aggtgtatta gtgaaggaat
    28381 attcatctag agagataaaa aaggatgata taaatgtcag taagtatata aaatatgctg
    28441 atttagcaag taaaaataat gcacaagtta actggaagta tgtagcttcc attgttgctg
    28501 tgttaaataa aaataactta aaaaacgtta aggattcaca gatacaagaa gtatcagatt
    28561 tatttgttaa gaatttttct aaaaataata aaataaataa gttaagtgat attttggatg
    28621 agttagaatt tagtaataga caaaaaagat tggttgataa ttatatagac aatcttaagg
    28681 attatggtat aaaaccagaa agattgaagt ctgatacaaa atatatgaag tttattgatg
    28741 aaattaaaac agaagcaata caaaattata aggattataa aatacttcca tctataacta
    28801 ttgcacaagc tataatagaa tctagctggg gtaagtcaac tttggcaaaa caatataaca
    28861 atctatttgg tataaaggct gacgcttatt ggaaaggtaa gtcagtgact ttagaaacaa
    28921 aagaacattt agatacaatt atagatgata aatttagaat atatgatgat aaaaatgaat
    28981 ctataaaaga ccatgcaaaa tttttagcca caaataaaag gtataaaaac aatggtgtat
    29041 ttgatgcaaa aacgtatata tatcaagcta aagcattaga aaaggcaggt tatagtactg
    29101 cgaaggatga aaatggcaat agtatatatg cagctcgtct aatagaatta attcaacagt
    29161 ataatcttca attaatagac agtgaaattc aaagtgaaat gtaactttga ttaaattttt
    29221 attgataagg ctatgatttt taaaatcata gccttatttt gacatgtttt tacttgtaat
    29281 tattaaatcg atatcattat ctttcaaaat ttactttata ctgtaaatca aattatttaa
    29341 gttaaaactt ggaattattt ataaaaggat tatttacttt atctaaattc tgcacttaaa
    29401 gaacatcttt tcccttaaga ctgaccgtta gtctataaaa attataatta cttataaaaa
    29461 agtgaataga gagatatata taattttcag aaagactttt acttgtaaat tgaaattaat
    29521 gaagtaaaaa aggattcttt cttgaaagta aataacaact agatagtgaa taataaaaaa
    29581 tggtaatttg aaataatttt tatgaatagt attaatatat agatacaggg agattgatgc
    29641 gattatgtat gaaaataata aggtaatata caaccttgaa agatgtgaaa aactagaaaa
    29701 gactctttat ttatctcaat ttaatacata taaaaatttt aaattagctt ctaaaaaaac
    29761 tgtaataaat tcattagaga catatgttta caatatgaat attaacaata taagtcttgt
    29821 tgatactata gaatgtatat cattagaaga tgaacaactt acaggaaaga agttgatttt
    29881 agttggtgat atagatattg atgcaatatt agattataca ggaaataaaa gaaatagaaa
    29941 ttctagtaaa aaaaatacat ttaaattaaa aatacccttt agtacattta tacaaatgcc
    30001 tagaaagata gaaaataaag ataaaattaa tttaaagtat cttatacaag atattacttc
    30061 atctatttta gatgataatt tatttattag tgttactgca attataagtt atgaaaatag
    30121 ttccaagata gagtaatctt taaattatag aaaggtggat gcaatgagaa taacgaaaac
    30181 tacttttaat gatgtatttt caaatgatgc aaatggaagt attataaaag tagaaaaata
    30241 tgttgataaa aaatgtgcat ctgtatttga gattttgacc tacactatta ttgttacaaa
    30301 tacaagtagg tacaaaactg gaaatatatt tttcaaagat tatatttcta aatatataga
    30361 gtttataaat aatacggtaa aagttaatgg aattataaaa cgtggattag acccacagca
    30421 aggtttttac atagggagaa tagatgcaag ttgtaaaaaa ataatatctt ttaagagtgt
    30481 agttttacca aattctgcac ataggattat aaagaatagt gctaatatat actattatta
    30541 taagtgtaat ctagataaat tcccaacaag aatatcaata gaaagtaata gagtttatac
    30601 taatgtaaat aaaattgtat tcaaacaatt gaatataagt aatactttaa aagctcctaa
    30661 aaatctaaga gatatattaa aagtaaatgt aaatagtaaa atatttgatg ttaaacctat
    30721 gaaaaatctt ataaacaaag gtagtaattt gaaattatgt aacttgatag tttttgggtg
    30781 tatagaagtt gaaatagact atagttgtaa aaataggagt aattttaaaa cagtaaataa
    30841 gtctaatgac attaaaaaag ataagtatta taaaaatgat atacaaaata acaatgaaaa
    30901 tataaacgat tgtaaaaagc aaataagttt tggtgataat aaggtaaaaa aaataacaaa
    30961 aacttttgga ttttcttgtt tcatttgttc tccagttgga attatttatg aagatatgaa
    31021 aaatataaat ataaaaattg aacatacatc aataaatgaa ttaaatccag aagaattatt
    31081 tgtaaataca tcacttttat tgtattatta agtattttaa agctaaaact taaacttatt
    31141 aaaatagcat ttggttaaag gaaaatagat attgatatat ttatcatata tataaatgat
    31201 taattaaaca attataaata ataagtatat tataatattt aaaaaatata gatttatgat
    31261 aaaataagac aaatatgtta aaaaaatgat aatcacggag aacttttacc ttcttcaatt
    31321 aatatattat tattagtaat aactttaaaa ttatattact attatataaa aattggctta
    31381 aaagaaggtg aaaaaagtaa atgaaaatat gcataacagt aggtcatagt atactaaaag
    31441 gtggtaaaag tacaggtgta aatggtatag ttgatgaata caattataat aaaaaattag
    31501 ctcctatgtt agctgagatg cttataagtc aaggtaatac agtagatgta ataatttgtc
    31561 cagaaaggca ctttatgtca gaaagagaag aatttttcta tagagttcca aaagtaaaca
    31621 gtggtaaata cgatttatta gtagagctac atttaaataa agctgatgga acacaatgtg
    31681 gtacagaagt gctttactat ggcactgaag gattagaata tgctaaaaga gtatctaata
    31741 gacttggaga attatttgaa aatagaggag ctaaaaaaag agaaaattta tatatattga
    31801 gaaatacaaa tccagttgca atacagattg aaagtttttt ctgtgataat gtgaatgatt
    31861 gtaacaaagc aaatgaatca ggttatgatt atatagcacg attgattaca gaaggtatat
    31921 tgaataaaga tataaatatg tgagattatg gtgatttagg tattgattaa taccttttaa
    31981 tattagatat aaataaaaat acaatgtatt agtataattt aaactttcaa aagatagatt
    32041 agtttgatta ttgacaagag atacctcctt gaaaatattg atttatcagt atatttaagg
    32101 aggtatttaa atataaaaat ttaattaatt tgctactaaa ctataggttt atagagtata
    32161 tacttttatc ttcagtctaa taaataatat aaaaatagta gaaccttgta ttataataat
    32221 ataatgtaga aaaatatata gataagataa atataataag gtggtaatat atgaaatata
    32281 catttgaaaa atttaagtta aatgaaaaga tacttaagtc attgaagagt ttaggatata
    32341 atataccttc tagagtacaa agagaagtta ttccaaaatt attaaaaggt caaaacttag
    32401 tagttaggtc aaaaacagga agtggaaaga cagcaagttt tgcaatacct ttatgcgaga
    32461 atataagtgt agattacaat aatattcaag ctcttatagt ggttccaaca agagaattag
    32521 ccttgcaagt aaaagatgag atatcagata tagggagact aaagaaggtg agatgtagtg
    32581 ctatatttgg caaacaatct ataaaagacc aaatagctga attgaaacaa agggttcata
    32641 ttgttgtagc tactccaggc agaatacttg accatataaa tagaggttct attaagttgg
    32701 aaaatgtaaa gtatttagta atagatgagg cagataaaat gtttaataaa ggttttgttg
    32761 aacaaatgga aaaaatatta ttaaatttac ctaaggagaa aatagtaagt cttttttcag
    32821 ctacaataaa tgaagagata aaatatatat gtgaaaaata tatgctagat tacagtgtta
    32881 taaatataga agaaaatgag agcgatacta atcaaaaaac aagacaaata gatgacaaaa
    32941 taatcaaggc aaatggaaga gagaagtaca tccttttaaa agaattaata tacagcgaaa
    33001 atccaaagag tgtgataata ttttgtaata ccaaagagaa agtatctaaa ttatataata
    33061 agatgagtaa agagggtttt ttaataagag agttacatgc agatttatca caagaaagaa
    33121 gaatttttgt aattaaggat tttaaaaacc aaaaatttaa tgtattagtt agtagtgatg
    33181 tagcgtctag aggaatacat attgatgata tttctttagt aataaattat gatgtaccac
    33241 aagataaaga aaactatata catagaatag gtagaactgg gagaaaagga aatagtggaa
    33301 aggcaattac tatagtaact gaaaaggatg aaaaatatat agagaatata gaaacgtata
    33361 taggatataa aataaatgaa ttaaaagata tagaaaaaag tagaattaca catggcaaaa
    33421 ttttgtttga agaatattca aaaggaatcc taaaaaaagt tgacaaaaat tcttacaaaa
    33481 gtaaagatat aaaactaaat atagaaagtg aagttgttaa attatattta aatgctggta
    33541 agaagaagaa aataagagtt ttagatatag ttggtgcatt tagtaatata aaaggtataa
    33601 ctaatgatga tataggtgta attgaagttc aagatttatg ttcatatgta gatatattaa
    33661 attataaggg agatttgata ttaaaaaaat ataaggagat acctataaag aaaaaaatgg
    33721 ttaaagtgaa aagagatata cgataattta gtcaatattg atgaattgct ttgttatcga
    33781 aatgaagttg caaaaaacac aatagaagtt gttaaggatt tgaaagctga agatatgaaa
    33841 cgaaaggtct ctccaattga cttagaaagg attttggtga ctggaggagt aataaagcat
    33901 gaagattcta tttggttgtt ggacttttgg gggaataaag atattgctgg aattttgctt
    33961 atgcctccta ctcgtcatgt tatacttcat ttgaatgatt gttgtaaatg gaaggaatat
    34021 tttcgtacaa aaaagaaatt ttacagaagt taaattataa taaattagac aaacaataga
    34081 taaattagca aggaatgttg attttatcta cattctaagt tatactattt ttaagtggct
    34141 aagggaatag tcattttaaa tataagtaat aaatatatac ctatagggat attaaagggg
    34201 ggaaatatat ggcatatttt aactataacg acaaacagtg ctactataat gaaattgggg
    34261 atggtacacc attacttttt ttacatggaa atacagcctc ttccaagatg tttaatgata
    34321 taatcaattt ttataaagat gaatataaag taatattaat tgattttgta ggtcatggaa
    34381 aatctcaaat ggtcgataaa ttttctgctg acttatggtt tgatgaggct atgcaagtga
    34441 tatgtttttt agaagcaatg aactataaaa aagtaaacat aattggtagt agtggaggag
    34501 ctcttgttgc attaaatgtt gcacttgaga gacctgattt agtgaataag gtaattgcag
    34561 atagttttga aggagaagtt cctctagagt catttgtaca aaatgtgaaa atagagcgtg
    34621 aagcatctaa gcaagatgat ggtgcaaaag ctttttatat ttataatcaa ggagaaaact
    34681 gggaaaaagt tgtagataat gatacagaag ctatttttga acattataaa actataggaa
    34741 agttttttca taagcctcta gaaactatgc aaccagaggt gcttttaaca ggaagtagag
    34801 aagatgagtt tgtatctcta atatctagtg atttttttga aaatactttt tcattacttc
    34861 ttgaaaagat taaaaatggt aaaatgtatt tgtttgataa aggtggtcat cctgcaattt
    34921 tatcgaatgg attagatttt tcaaatgtag caaagaaatt tttagaggaa taatttaacc
    34981 aaaatttaca ataatgaaaa ctgtaaaatg gattgcaaaa cttacaaaag tgagtgtaca
    35041 tatacttcat tattatgatg aaataggatt gttaaaacaa aatattctaa tagtcaagtt
    35101 attacatttg tatatgcaat atgtatagaa agagatatca ttagattgta aagtttggat
    35161 taaataacaa tattaaattt tatttattca gatattttag cttaactata taaatgttag
    35221 aacaaattta tatagttaag ctgtaggatt aaataattta gttaaataag tttattatct
    35281 cctcatcaga tagacttttt aatacacctt cattagaaag ttctccattt ataaattgat
    35341 ttataagctc ttttttactt tcttgtaatt ttattatttt ttcttctata gtccctttag
    35401 caatcaattt tataacttgt actgaatttt tttgaccaaa tctatgagct ctatcactag
    35461 cttgattttc tactgatgga ttccaccatg ggtcaaagtg aattaccatg tcagcagatg
    35521 taagatttaa accagttccg cctgctttta aagatattaa aaaaactttt ttatccatac
    35581 tattattgaa ctcatctaca agttcaagtc tttctttggc attagtttta ccatctatat
    35641 aatggtattt aattttatac ttatcaagtt ccttacttat gttcttaagc acagaagtaa
    35701 attgtgaaaa caataatatt ttgtggtttt cgtttatact atccctaagt atttctaaac
    35761 atgtttcaat ttttgaactt tttttattgt aatcttttac tactatactt gggtctaaac
    35821 aaagttgtct tagtttagtt aaataagaaa atataactat tttatctttc tttaaatttt
    35881 tatctttcat tttatcttgt atatcttttg aatatacact atatatcttt ttctgctctt
    35941 tattcaattc aacaaaaaag tttttttcaa tcttatctgg aagttctttc ataacttgtt
    36001 ttttacttct tctaagaata aaaggtttta tcaatttttt caggttttta acattatctt
    36061 ctttatttat aaacaattcc tgaaactttg ctttactata tagatagcca ggcattataa
    36121 aatcaaatat agaccataat tctagtagat tattttccat aggtgtacca gtgagtgcaa
    36181 atttattttc tgcatttata ctttttacag actcagttac taaagctact ggatttttta
    36241 tattttgagc ttcgtctaat atacaataat caaactttat ttcactatat ttttctaaat
    36301 catttctaag agtaccatat gttgtaagta ttacatcaaa attttctaat tccataaaac
    36361 atttttctct atctctttta tttccatgta tcaataaaac ttttatatct ggagcaaact
    36421 tttcaaattc atttttccaa ttataaatga gtgatgtcgg tgtaacaata agactttttt
    36481 tattagataa tgataataaa aatgcaatag tctgtattgt tttaccaaga cccatttcat
    36541 cagctaatat accaccaaat ttataataat ctaaaacttt aaaccaattg aggccattta
    36601 tttgatagtc acgaaggttt gcatttaaat ttgcgggaat ttctaaattt atgctatcaa
    36661 aatttctaaa tttttcacat atactgtcta gttctttttt accatctata aactttaaat
    36721 ttttactacg tattacatca tttatatata gagctttgtt tttatgaatt ttattatttt
    36781 ttgatttatc cattatatct agattttcaa ctaattcaaa aaaatctttt gtttctcttt
    36841 ctgataaatc tataaagttt ccatctttaa gtttataaaa agtacgtttt tcttgaaaag
    36901 ctttcaaaat atccttgtac tcttttggat ttatatcaga tatattaaaa ttaaattcta
    36961 ggtaattctg gttagtctga ttgattgaag cttgaattga tgaagcgtta tatatttttt
    37021 tcaatttaaa cttctcagaa taatatatat ctccaaattc ctttagagat tctaattgta
    37081 aatctaaaaa tgtaaatagg tcatggtcag ttcctttaaa cacataatga ttattttcct
    37141 ttgtaaattg tgaagaagta agtttatttt caatagtagc ttccttttgt atgttgggga
    37201 gcacaaattt tttatcttca tcatcatata tatactttac atcacaacat atgttgccat
    37261 caatcatatc aaagtagaac tcagatttaa aatcttttgt tatattattt tttatgttat
    37321 catctaaatg aacttcttga gatatagatt ttaatctagg aactagcaat cctaaaacat
    37381 ccttagaatc ctctttatca aattttaact ctttagtctt tgataatatt tgatatattt
    37441 ttgaataatc atgagctttt ttatgtgata ataaatagat attgccatca tataaaagta
    37501 catcattttt tttagtaagt ggaacaggta gtgaatcttt agaatataag actattttat
    37561 cttctatatt tttaaaatca aaccttacag gtagagtatc atttaatatc tttggatgat
    37621 attcctcttt agaaaaaata agggtaaaat ccttgtactt aatagcattt aaaaattgtt
    37681 ttaaagagct tgcatttatc tccataaatt tttttgaatg tgatgaagaa aagttgtatg
    37741 aaagatttgt cccatattct tctataatat ctactaactt ctcatcttca tcagcaaaat
    37801 aatgaatgtt ggggttgtaa gtaaatttct tcccaaaatc taattcatat ccattaagtt
    37861 ttgaatatgc aaattcagta atatttttta aaatgtacat tttatcaatt cctattttaa
    37921 attcagcaat tgctttattt gaatccacat ttatcaatac atctaaatta accctttctc
    37981 ttttagtatt gtctaacaaa gaaagtaatt gcttgcttaa atctaagctg gttttagaat
    38041 ttgtattaga aagcttatcc ttatctgcac ctaatatatc tattagaata ggaggaacat
    38101 cttttttatt ttttatttgt tttaagcttt ttatcacaat agcaactata tgcttacata
    38161 taaaaatact tttgcccttt gattgacagt cagcgcaact acaatcattt tcaattatct
    38221 taaagtgctt tatatctata gttattgaat taaaataaaa gctataatta tcttcagaat
    38281 tgactccacc acgaaatgtc aacaggttat tttgtaggtc atcaatatct atgtctatat
    38341 aatcaactaa ttgattagta taatatttta cacctcttga ccatcttgat ggttctgtat
    38401 ttcttcttat tagtttatat atcatatcta ttttcatatt attcacctta cctcactgta
    38461 tatattataa tctaaatgca ttcaatttac actctaaatt taagactaaa attaaggcag
    38521 atatgaatag cttttatcta tcacaatata tgtgtaaata acaatttact attagatttt
    38581 tattgaatta tcttataaac tatga
//
LOCUS       DAEORM030000038        38402 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.038, whole genome shotgun sequence.
ACCESSION   DAEORM030000038 DAEORM030000000
VERSION     DAEORM030000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 38402)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38402)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 38402)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38402
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.038"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            complement(88..699)
                     /locus_tag="KRH23_002424"
     CDS             complement(88..699)
                     /locus_tag="KRH23_002424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HHS5225702.1"
                     /translation="MKMVKKLILSTIMALVLVLTIGCSNAEEKVKSNFEANLAALEMY
                     KYDEKGISDALTEAEYKQIQTYNSKDKVSMIAQLTPLYGKENAEKIYETIVKLIQGVE
                     KTVTVESSSKDKITLKVVSKALDTSKVMSEANTLVKSYVTDEKNYDKKEKEVQDDMTK
                     MIIDLYNKKPTKEVTTMITYTKKDGKWQPPSNIQKLCEGIYTI"
     gene            complement(791..1780)
                     /locus_tag="KRH23_002425"
     CDS             complement(791..1780)
                     /locus_tag="KRH23_002425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HHS5225703.1"
                     /translation="MLLLKKDDIKKVFTMRDAIEADKEAFRIYCEGKSVNPLRTNISV
                     PSQDASMLFMPGYVEELGCGGIKIVSVFPKNAQKGKPVIPAAVLLLDGETGEVSAVLD
                     GTYVTQIRTGAASGAAIDVLAKKDSKIGALIGLGGQGEPQLEAMIEARNLDEVRVFSR
                     NKESREKFAEEMNLKLSKYNTKIVAVESSDEAIDNADVIVLATPSKQPVLNGNLVKKG
                     ALISAVGSYMPDMQELCPNCLTRASKIFFESTDAVLSESGDILIPLKEGKISKDDFSG
                     DLGNVINGTIPGREDDDEIIVFKTVGIGVQDVVTAKRIYDKAKENGIGIDWKW"
     gene            complement(1847..2710)
                     /locus_tag="KRH23_002426"
     CDS             complement(1847..2710)
                     /locus_tag="KRH23_002426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 and DUF4163 domain-containing protein"
                     /protein_id="HHS5225704.1"
                     /translation="MKFFKVDTKAKVLRYVFVLTLTIMAVLAIKHDYKYNNLRKDASI
                     NLNSNKEAVTVMSNQSLPKGNTNSKQTLSVSTIGSKTIVKNDEYLESTINMPVITNSN
                     KIVERSTNDKIKNDIFEFYNKSYKEAKQYLKDNPDEKNKFVANVDFELKKNTDSALSI
                     KVRYYTYSGGAHGFYQDVAYNVDMRTGKFLELMDLFKDNTKYKEVIDEEIKRQIAELE
                     KKDEENIGIYNFKGIKENQNFYLQDENLVVYFDLYDITPYAAGIPEFSINKALISSML
                     KPEYVDLFDLK"
     gene            complement(2816..3412)
                     /locus_tag="KRH23_002427"
     CDS             complement(2816..3412)
                     /locus_tag="KRH23_002427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CheB methylesterase domain-containing protein"
                     /protein_id="HHS5225705.1"
                     /translation="MERFNNMVIAIGASVGGTEAILEIIKDLPKSTPGIVVVQHMPAI
                     FTYMYAQRLDKQCIMNVREAKNNDRVEQGNVLIAPGGYQMKLCTDKQGYYVTCEKGER
                     ISGHCPSVDVLFDSVAEVAGKNSIGIILTGMGYDGANGLLKMKENGSFTIGQDENSCI
                     VYGMPMVAFDRGSVMLQLPLGEISNCLIRHINILKQKD"
     gene            complement(3452..4255)
                     /locus_tag="KRH23_002428"
     CDS             complement(3452..4255)
                     /locus_tag="KRH23_002428"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CheR family methyltransferase"
                     /protein_id="HHS5225706.1"
                     /translation="MIKLTDEEFIVLVNHVKKEYGIDLSKKRALIEGRLYNTMIEKKL
                     SSFSQYMNLLFKDKTGNEAINLINRLSTNHTFFMREPQHFEFIQNSILPFWEENNKIR
                     NINIWSAGCSSGEEAYSIAMTLDDYFGYNKELWNIKIIATDISTNSLEKAKRGIYIES
                     NVNNVPELWKKKYFIDNKDGTFKICDKIRKSVIFKPFNLMNDFSYQHFDLIFCRNVMI
                     YFDLKTREELINKFYNATKKDSFLFVGHAEVINRSSTKYKYVKPAIYKR"
     gene            complement(4291..4731)
                     /locus_tag="KRH23_002429"
     CDS             complement(4291..4731)
                     /locus_tag="KRH23_002429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006935 - chemotaxis [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheW"
                     /protein_id="HHS5225707.1"
                     /translation="MAKDEIIKQVLTFYVNDVIYGIELENVIETIRFQSITYVPCLPT
                     YISGVINLRGRIIPVINMHIKYNLPKADYNERTCIIITKVDEYQVGIIVDKVVDVIHI
                     ENLNLLETTNSNNTNINKDIKEIAKVEDNSILILDIRKFLINSM"
     gene            complement(4744..6846)
                     /locus_tag="KRH23_002430"
     CDS             complement(4744..6846)
                     /locus_tag="KRH23_002430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006935 - chemotaxis [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheW"
                     /protein_id="HHS5225708.1"
                     /translation="MRQMLDMFIFETSLLLEQLDEIMIQIEKEKVFTHNNINETFRIM
                     HTIKGSASMMGLDNISALAHSVEDLFYAIREGKIEVLDNDLLFDLVFQSLDFIRRDID
                     ELQSRGCISSDYSNFIEGIEEYVSTLELSSSMKSKDNANLESKDEKEVIDSNFEYKED
                     SDVVKIIFEQGCMMENVRAFMLVFELRDYCEFIDFYPKDVETNAESTEYIKSYGFYIQ
                     FVAKEDKAIVYKTIEDNLYVKEYINISKKEIEMKNTSNNDAVENKLKDNNKVSKSYQN
                     NYTEDEIQEDVLNEKTDMEKDSLSEENEHLPISKQSIMSVNLEKLDLLQNIVGEIVIM
                     ESMVVNSVNSTGVDIDNFNKATRQLHKLTDELQDIVMSMRMIQIAGVFQKMHRIVRDM
                     NKKLDKNVELITIGAETEVDKSVIDNLAEPFMHLIRNAMDHAIEPIEERIAKGKEEVG
                     KIVLSAENLGGEAVISISDDGRGIMRDKILAKAKEQGLLKHQSNEYTDDEVNSLIMTP
                     GFSTKESITEFSGRGVGMDIVRKSIEKVGGSIEVKSKQDEGTTFTIKIPLTLSIVEGM
                     KFKVGDSLFTLPISSIRRTFKLTDLNQIITEGNKTELITIYGACIPIIRLHKIYNIQT
                     KVTNLMNGNMIIIENEHKAVCIFVDEIIGNQQVVVKPFPVYFNRFNIKNKGLSGCTIL
                     GDGSISLIIDADSIIEIY"
     gene            complement(7111..8814)
                     /locus_tag="KRH23_002431"
     CDS             complement(7111..8814)
                     /locus_tag="KRH23_002431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0098561 - methyl accepting chemotaxis
                     protein complex [Evidence IEA];
                     GO_function: GO:0004888 - transmembrane signaling receptor
                     activity [Evidence IEA];
                     GO_process: GO:0006935 - chemotaxis [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing methyl-accepting
                     chemotaxis protein"
                     /protein_id="HHS5225709.1"
                     /translation="MKREVKLSKLAIVLLIIIVLAVLAGIFSSISSYKAFEKVEKSIN
                     DMNNLRTQSQYIKDTTREISDVLRRYVFTGEKKNKDIYEKELYGKTRESALNKLEKIG
                     LTKSESNKILEAKEISDSLVPTEQSAIKAVESNDKSKAQSIIFGSDYINSQEKMDSLI
                     NEFQEDIVTRSNSKIVEVKKELQSLILRTIFILSLLIILTIIEYTVIKLKIVIPINKV
                     EKHFSRIASGDLRTSIDVEESKSEIGLLVSSVKKMQSMLLNYIDLIDSTLTSIAKGDL
                     RVEIDQEFIGDFKSIKISLESIINSFNGDFSEINLSAEQVASASEQVAAGAQALSQGA
                     TEQASSVEELASTINEISDGIKKCADSASLACEVSDQSASQVGFGSRCMDDMMTSMGE
                     ISEKSSEISKIIKTIDEIAFQTNILALNAAVEAARAGQYGRGFAVVADEVRSLAGKSA
                     KAAQNTAILIEEAIKTVENGVRIAKETANALDLVVNGVEKTTNYINGISSAVHSQEVA
                     ITQILSGIEQISIVVQMNSATAEESAAASEEMSAQAQILKELVEKFHLKESEVRESSW
                     V"
     gene            complement(8840..9799)
                     /locus_tag="KRH23_002432"
     CDS             complement(8840..9799)
                     /locus_tag="KRH23_002432"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0052621 - diguanylate cyclase activity
                     [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing response regulator"
                     /protein_id="HHS5225710.1"
                     /translation="MKNKQQGTILVVDDSVLMCDLIDKTLTKDNFKVKKAFNAIEAKE
                     FIEEFIPDIILLDIILPDNSGFEFCKEVKSNARTADIPIIFITSKNTDTDIVKGFGVG
                     AIDYMVKPFSMTELKARVIAHLEVKKSQDKLKKINNELESSLEKLNRLVVRDYLTGLY
                     NRRHIINQLMEQRRINKYSETSISLILGDIDDFKVINDTYGHEAGDFVLTVISSIIKK
                     NCRQIDTVSRWGGEEFLIMLTNTPIEGAKILSERIRKEIKEFDFNYKEHKIKCTITLG
                     VVEVNSNISLEENISLADKAMYEGKNLGKDCSVVSTMKGLKKI"
     gene            complement(9935..10453)
                     /locus_tag="KRH23_002433"
     CDS             complement(9935..10453)
                     /locus_tag="KRH23_002433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006935 - chemotaxis [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheW"
                     /protein_id="HHS5225711.1"
                     /translation="MRFPDDPYLDYGLIDEGIKYLKFRVDEQDFGVELEKVIEITGNQ
                     EIIFIPELPTYSKGIINLRGKIIPIIDMRLRLKKDELMTTNCMYIVVTEIKDLVVGFV
                     VDRVDDIVSLEKSKISPPPRVTIEYSDYFVSGVGELEGKIITLLDLEKLLTDKDEVLI
                     DELINGFDCTIM"
     gene            complement(10496..10981)
                     /locus_tag="KRH23_002434"
     CDS             complement(10496..10981)
                     /locus_tag="KRH23_002434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheD"
                     /protein_id="HHS5225712.1"
                     /translation="MNREIVVNIADMKIAYRPNVLVTYALGSCVGVCLIDKVAGIGGM
                     LHVMLPYSKDAINIENKCKFADTGINELIKSMENIGANRIYIKAKIAGGAQMFLGSSN
                     SVIASIGHRNVEAVKKTLLGLNIPILAEDTGMNYGRTIRFYTETGELLVDSINKGKKK
                     L"
     gene            complement(10978..11625)
                     /locus_tag="KRH23_002435"
     CDS             complement(10978..11625)
                     /locus_tag="KRH23_002435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheC"
                     /protein_id="HHS5225713.1"
                     /translation="MNAIIKGGVYIINYLELDDVHIDALREIGNIGSGNAITALASMI
                     NSNVEVLIPMVKILEYNEATNLLGGPENKVVCILLDMKGDINGMFMFLLDESITQLML
                     SSLFNKEEAFLDEIEAIEISAIKEIGNIMASSYVNAIASMLNMTISVSIPDICIDMVG
                     AVLNVPMIRFSDVGDKVLFIENKFKMSDNYFTSHILMIPEMSSLREILVRLGLEV"
     gene            complement(11660..12022)
                     /locus_tag="KRH23_002436"
     CDS             complement(11660..12022)
                     /locus_tag="KRH23_002436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HHS5225714.1"
                     /translation="MENKILIVDDAIFMRMIIKEALSKSGYNNLIEANDGEEACNIFK
                     YEKPDLMLLDITMPKKDGLEVLREIKKLDSSAKVVMCSAIGQENMIVEAIKLGALDFI
                     VKPFKTETLVKVVNNVLK"
     gene            complement(12766..13263)
                     /locus_tag="KRH23_002437"
     CDS             complement(12766..13263)
                     /locus_tag="KRH23_002437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005488 - binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HHS5225715.1"
                     /translation="MNYEIVEINEKIVIGISKETTNKDGQAVNDIGELWKKFMGKGIY
                     NAIKGKKNDKTIGLYTDYQGDFTSPYSFVACCEVNSNSDKEKNLEELNTNNTVGESII
                     SKVIPAGKYAKFVIVGGQKEVGDFWFEFWQMDFDRTYISDFEEYQCNTFDTKKQEIHI
                     YIGIK"
     gene            complement(13438..14349)
                     /locus_tag="KRH23_002438"
     CDS             complement(13438..14349)
                     /locus_tag="KRH23_002438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HHS5225716.1"
                     /translation="MKINRLTEIIVILLNKKLVTAKELADRFEVSTRTIYRDIETLSM
                     SGVPVYMTKGKGGGISLIEEYSIDKAILSKKDKESLIVALKTLQATKYPEINSVVNKI
                     GSIFGEQNFSNWIEIDFTEWGSNFNEDDKFTKIKEAILRRNTINFNYVNSLSSQTNRT
                     VEPLKLMYKSKTWYLYGFCKLKDDFRIFRISRIRNLSIKDEVFSRKIIEEVCLNDSKV
                     IKENTITLKLRFKEKMLFRVFDDFNKDLITKNEDDTYDVITEFPIGEWIYGYILSFGD
                     NVEVLEPKDVRDNVITRLRELSKIYSL"
     gene            15097..15948
                     /locus_tag="KRH23_002439"
     CDS             15097..15948
                     /locus_tag="KRH23_002439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3100 domain-containing protein"
                     /protein_id="HHS5225717.1"
                     /translation="MEINKKHFIQVFLTCLILVVICEFIGQRTIAIGKASIVLFPMLY
                     AVIIGLIITPDLLGKKIKALKKVVGEKEINIAGEVVGIALVMLGIKYGTTVGPNIDKI
                     IQAGPAFIAQEFGHILAPIVALPLALMFGMKREAVGATASISREPSLGVISEKYGINS
                     PEGSGVLGTYLMGTVLGTIYFSVLGSISIYSGIHPYALGMACGVGSGSMMTAAAGSLS
                     TMVPPEMADTILAYAATSNMMSSITGIIFLVFVSLPFTNFMYKILEPKFSRNKKTKEI
                     KSTEGEC"
     gene            15952..16422
                     /locus_tag="KRH23_002440"
     CDS             15952..16422
                     /locus_tag="KRH23_002440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5225718.1"
                     /translation="MFANLNLKKSSYQLLVMSVIGVIILIGQRISVGTSIVTALPGMV
                     MLILAAMAAMIIKDLFPKSIFPAFGFATIIGLLLSMPYSPTSEVFLTNTNNINFMAIT
                     TPLLAFAGISVGNKIEALKEMSWKIVIISLIVFTTIFFACASIAHIVLSIQGKI"
     gene            16435..17745
                     /locus_tag="KRH23_002441"
     CDS             16435..17745
                     /locus_tag="KRH23_002441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HHS5225719.1"
                     /translation="MNKEQLKSLVIKTIDENREKILKIGQGIYKNPEYGYKEFKTTET
                     VSNFFEQELNLSVEKNIAVTGCKADANSSKKGPHISILGELDGISCKEHKDANEIGAS
                     HTCGHNIQIAGMLGAAVGLVKSGVLEHLDGKVSFMATPAEEFIELEYREQLKKEGKIT
                     YFGGKQELIKRGYFDDIDISMMFHASDLGEDKALVGPESNGFVGKKVKFIGKESHAGS
                     APHDGINALNAAMLAINNVNALRETFKESERVRFHPIITKGGDIVNVVPADVHMESYV
                     RARTINGMIDANERINKALMAGGMAVGADVEITEIPGYLPILRYKSLDNLFKNNLEDL
                     GLKGKVIDGGDFTGSFDFGDVSHIMPTLHPMIGGVKGALHTRDFEIVDEDLAYIIPAK
                     AMALTVVDLLFDNAKDAKDILDTFTPVMTKEEYLTFLEKHDKTL"
     gene            17957..18703
                     /locus_tag="KRH23_002442"
     CDS             17957..18703
                     /locus_tag="KRH23_002442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HHS5225720.1"
                     /translation="MFNAGNRIINTWLYPIQDGFVLIDTGYENGFKHFKKRISKFNIK
                     IKDIRYIFLTHAHDDHVGFLNQILDESPNTKIVMHDKALEILYKGQNSFIGGCTSRTA
                     FLFCQIMKLFGKGEHSFSPLKQEFEKRCILVSDKNRKEIEKELNGKIIDTPGHTADSI
                     SLLIDDGVLFCGDSAMNGFPSTHKITIFAESKLEFIQSWKTIINTKPKMIYPGHGKPF
                     EYSKLEQNLIYVNKINLYPLHNSKDIHRFL"
     gene            19064..20605
                     /locus_tag="KRH23_002443"
     CDS             19064..20605
                     /locus_tag="KRH23_002443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbgT family transporter"
                     /protein_id="HHS5225721.1"
                     /translation="MNDNVVKKKNFFDRTLNRIETVGNKLPDPVTIFLGLCVLLLILS
                     SLVGSMGISVVHPGTGETITAVNLLTVEQLQILLGNIVSNFQGFAPLGLVLVTMIGAG
                     VCDKTGLMTATIKASVSKIPETRVTLVVMTIGMLANIASDAGTILFPPLAALVYLGVG
                     RHPLIGLFSGYAAVCLGFAANIMISVNDILAASFTVPAAQMIDSGFQANATMNLFFMI
                     ASTFVLILLATWVTEKIVAPRFGKYEGNAELDVDGSLSDVEKKGLKKAGISILIYVAI
                     IVALSVIGKKPFLADPETGDLLSNNAPLMKGMVPIIALAFFIPGVVYGKTIGKIKKDK
                     DVVSIMASAMSDMGGYIILAFAASQFLQLFTNSNLGLILAVKGGEFLKSAGINGPLLL
                     IGFIILSCFINLFIGSASAKWAILAPIFVPMFMMVGYNPALTQMAYRIGDCITNPLSP
                     LFPYFPIILAFTRKYDKDAGMGTVIANMLPYSISFLIVWTILLILFMVFNIPLGPGIL
                     PSYSM"
     gene            20640..21746
                     /locus_tag="KRH23_002444"
     CDS             20640..21746
                     /locus_tag="KRH23_002444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HHS5225722.1"
                     /translation="MLDKNRLINNFMDMVRIDSPSNQELEMSKWLVNYLKERNIDAII
                     DDAGEKYGGNTGNVIAYIKGEEGSRPLCLCAHMDQVQPCLGVKPILDGNVVRSDGTTT
                     LGADDKAGIAAILEALEHVITEKIPHRDIYLCFTICEEAGMHGVKNFNPDNLPCKDMV
                     ILDSGGAIGSIAYKAPAQQSIKISFHGKKAHAGIEPEKGLNAILVASHAISNMHIGRI
                     DSLTTSNIGKIEGGGATNIVTDKVTLTAEIRSHIPETLEYELNHMEKCCKDAASKFNT
                     TYTFEHNMSYPSFELSRDSHVFKLSEEAIRQVGVVPNPMVIGGGSDANILANLGYNCA
                     ILSLGMYDVHTVNEYVNIDELYDTAKIVYHMIKL"
     gene            complement(21956..23242)
                     /locus_tag="KRH23_002445"
     CDS             complement(21956..23242)
                     /locus_tag="KRH23_002445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HHS5225723.1"
                     /translation="MIVGIIGPSDSGFKIKDDLKQIDSDLKTKIYVREKVVDTIEVIS
                     KCEDECDAIIFTGCAVYEFIKSKYEISKPHSFVPRSGTSIMKAFWAIKSANIKLDKFS
                     IDVVDRYVVEDALKEFDIKATSVFCNPFSLEVGESELVEWHIKLFEENKTDIMLTGFG
                     AVYNELKERGYPVFRLQATIQLIKESYDKVKSEYALSKARFSQIAVEILSLIDYKEKI
                     DNYYSDMIKKSDMDKLVVNYVRSIQGSLFLLGRNDYVVFVHKGVADNEYNYDKLFNLK
                     REIKDMGFSLSIGIGTGVTAYQAENNAHKALRHSIDSKEIGIYLVDEDENIRGPLASE
                     NELNYSLMLSDEKVIEISKKTGMSCESVAKIIAINENRKSKIYDSKELAEYLNVSERS
                     ARRILNKIVNAGLGRICAKETSIGGGRPKNITEILF"
     gene            complement(23365..26463)
                     /locus_tag="KRH23_002446"
     CDS             complement(23365..26463)
                     /locus_tag="KRH23_002446"
                     /EC_number="2.7.7.65"
                     /EC_number="3.1.4.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0052621 - diguanylate cyclase activity
                     [Evidence IEA];
                     GO_function: GO:0071111 - cyclic-guanylate-specific
                     phosphodiesterase activity [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="HHS5225724.1"
                     /translation="MDVINLIDELDEIVYVSSLDTYELLYINEIGKKAMGLNDISHLK
                     CYKALQGKDSPCEFCTNSILKEDEYYIWENTNTRTNRHFILKDKLIKWEGKHARLEIA
                     LDITEKEDISKSIAEKLEIKELLVGCIKHLITESNFSDAVNLVLTNIGKFHKADRAYV
                     FEVSEDRTKVTNTYEWCNEGVDEQKQALTNLDINELKNWFLLFEQKGFVIIDDIENIK
                     EEQPIEYEILKPQKIESLMTSSLKQDDKVVGFIGVDNPHKAVGDTSLLTSLSYFLLTE
                     MKKRKVENKLNYMSYYDFLTGAYNRNKYIKYIDNFQKGKVKSIGVVFVDINGLKDIND
                     NFGHANGDSAIVSACVIIKKYFHSYNVYRIGGDEFVVLCEDISKQLFEELVSWLSEEF
                     KDEMIYSVAVGSIWSDDNIDIHKLIKVADERMYQDKKRYYNKNKLRNNEMKVISDLAD
                     STNNILFKHKELVDKVYFDDLMIKGYSKAYEKLAYNTYDIILSICIDTNLITPIYQSE
                     SNIFSFPIKENLEKTFSYIKKHLIHPDDIILFNDNHLLKSLDSLNNSKQDDLELNFEY
                     RRLGIDKKYYWALIYMLKISSKNKLGEKQTHILVAIKNIDYLMQLHKNQKDTLTGLYN
                     YESFCEQISLMLKRYPDKRYAIIMMDIDKFKVINDIYGVRGGDKALIYVAELIQKNIG
                     SNGICCRMYADVFCIFYESYSDRDIHKVIYKIKNSLNRKKFEYMLVPCFGVYRILDNH
                     IPITNACEMAGYAHKKVKKQSINNYIFYDDTIRNDALEEKQMEREMEYALENGQFHVY
                     LQPKYNLNANKIVGAEALVRWVHPEKGIIPPIKFISLFEKNGFIIRLDMYVWEQVCSL
                     IRKWIDLGEEPVPISVNVSRLHLHNPHFKEIVLSLINKYSIPKSFLELELTESLFIKN
                     IKLFTKIIADLRMDGIVLNMDDFGSAYSSLNMLKNINIDTLKIDCGFFNEEGITDREK
                     IVLKHTIAMAKDLDMDVVAEGVETKEQAEFLVSLDCVVIQGYYYCKPIPSADFEKLLY
                     QK"
     gene            27188..27340
                     /locus_tag="KRH23_002447"
     CDS             27188..27340
                     /locus_tag="KRH23_002447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5225725.1"
                     /translation="MKIFSFLLFVIGICLCIAGFIGHYPVFVGTTLSFLAIAMIAVRQ
                     VKTKKK"
     gene            complement(27632..28336)
                     /locus_tag="KRH23_002448"
     CDS             complement(27632..28336)
                     /locus_tag="KRH23_002448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HHS5225726.1"
                     /translation="MEIKPLVLIVEDDKPICKFIKVSLETQNYRCVETDNGGTAISLI
                     HSLDPDLIILDLGLPDIDGIEVIGRVRACAKTNKIIVVSAREHERDKVEALDGGADDY
                     LTKPFSVTELLARVRVALRNKAQQDNINNDAPKSFEVKNLKIDYENHIVSINGEEIHL
                     TPIEYKIIELMSKYSGRVLTHKFIIDKVWGNYYESENQSLRVFMASIRRKIEKNPAQP
                     EYILTEVGVGYRMADE"
     gene            complement(28327..29934)
                     /locus_tag="KRH23_002449"
     CDS             complement(28327..29934)
                     /locus_tag="KRH23_002449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4118 domain-containing protein"
                     /protein_id="HHS5225727.1"
                     /translation="MKKERLQHEDLKEYDYDEDGYLSKKIIIKDFIKTILVMTIATGI
                     SVVFEKVGFNESNIILVYILGVLFATSITYGYFFGILSSVIGVLSFNFFFTHPLYTFL
                     AYRKDYPMTFCIMLMAAIITSTLTSRIKREVRLSHKREKMIRLLYENNKTLLKAKNKN
                     QIIEFCGSNLVNILNRTVIVTIADENNNLGKPSIYICNNDGSENIFHSVLEKEAIKEA
                     FRTGNPVGIGTKYCKNSSAYYFPIKGQESNVLGVIGVACFKIDIITENEKILLEAVST
                     QVALAIDRENLFEKNKKANLEAERERLRGNLLRSISHDLRTPLTSILGSSSTILENDD
                     VIDKETRVELLKNIYEDTSWLTHSVENILSMTRIDEGKLDIEKRPEVVDEIIAESILR
                     VKKFANSRYIKTNIPDEIIIVHVDVLLIEQVLVNLIDNAIRHTPKNSKIELTVKKESN
                     QVLFEVADNGKGIPNEDIGNIFNRFYTKNKSRNLERRGIGLGLEICKSIVEAHGGEIV
                     AFNNPSGGATFRFSIPMYDEEGKDKWK"
     gene            complement(30188..31366)
                     /locus_tag="KRH23_002450"
     CDS             complement(30188..31366)
                     /locus_tag="KRH23_002450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CD0519/CD1768 family membrane protein"
                     /protein_id="HHS5225728.1"
                     /translation="MEKLSDKRRVKAVSMETFVFIVLLAVGFGYVGSIMGAGMMFKVI
                     MSTAHALLLDTVFLIMAMAVLAGALSALLSEFGVISLVNKIFKGLMRPIWGLPGASIA
                     GVVATYLSDNPAIIPFAKDKTFTQYFKKYQVPALCNLGTAFGMGLIVTTFMIAQGKEY
                     VLPAIIGNVAAIIGSIISVRIMLTFTKKYYNYDPKNDTEKQINDKGAKLEEFREIRDG
                     NVFQRTLDAILEGGKLGVEMGMAIIPGVLVVCTLVMLLTFGPSTDPATGQAVYTGAAY
                     EGIKLLPAIGDKISFIIEPLFGFTSPEAIAFPVTALGAVGAAISLVPEFIKSGAITPN
                     DIAVFTAMGMCWSGYLSTHIGMMDALDARPLAGKAILSHTIGGLCAGICAHFIFMLVG
                     "
     gene            complement(31592..32086)
                     /locus_tag="KRH23_002451"
     CDS             complement(31592..32086)
                     /locus_tag="KRH23_002451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HHS5225729.1"
                     /translation="MHLFIEVIAAFFTALSFGVLFNMKGKNLILAGIGGSIAWFSYKF
                     LLNMGVTENLCFFIATVCFAIYCELCARIYMTPATTLSVCCLIILVPGYGIYNTMYSV
                     LTNNYIKAVEYGVSTLSCASSIALGLVFITTVFRKVNLYGVLTKIKENEKYKKSINKI
                     KQQK"
     gene            complement(32087..32848)
                     /locus_tag="KRH23_002452"
     CDS             complement(32087..32848)
                     /locus_tag="KRH23_002452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HHS5225730.1"
                     /translation="MDIDRILNFSSNAGKAMLQSGGETYRVEETIARICQSFGIDHVD
                     VFATPTAVMASVFVDGKLHSAIKRISSRRVDLNLVHEVNSLSRAISINNLDIELCEKI
                     LDEISEDNYYSDLITIFFAGIAAATFSILFGGNVEEFIAAFTVGILTKFVIMYLSKSS
                     LNDFFVNAIGAVIIASCSILILKLGFIKTLDHLIAGAIMLLVPGLALTNALRDLLDGQ
                     LISGLAKLAEVFFVGVSIAVGMFLVLGLYFKLGGI"
     gene            33550..36384
                     /locus_tag="KRH23_002453"
     CDS             33550..36384
                     /locus_tag="KRH23_002453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HHS5225731.1"
                     /translation="MLRKDKVLLSLHKLCENMTLKDLQSDKTGFTTIEIANHSSLDRS
                     NTSKELNNLYNEKKVLKISGKPILFLHASIIENLIGRTLNSDEFSINNCNELLKSSKN
                     DSEDIFSTLLGHDSSLKLPIEKAKSAILYPPKGLNTLLIGPTGVGKSTFAETMYKYAV
                     ESKIFSSESKFVVFNCAEYAENANLLLSNLFGYVKGSFTGANKDKFGIVAQADGGILF
                     LDEIHRLPPEGQEMLFLLMDKGIYRRLGESDIVHKANVFIVCATTEDIHSSLLGTFLR
                     RIPVTINLPALQDRSLKERLSLIKYFFIIESKYTNATIKVHKDVIKSLLLYDCFGNIG
                     QLKSDIQLMSARAFLNYKTGLKDNIEIDLSLVPDYIYIGLLKLNENRSNLNKLSELDY
                     MLFYEFNGNNLEVEYTKELSKYNIDTSNNGFKYSTEIPYLENDIRSMFINYMEKYSTK
                     LLSISSVTHSDYTSNEIFKVINPKIYYAVEHSLKEAEKISRNKYTKQTYIALSMHISA
                     LIENINQDTYNPKYNLYNDKIFLDKDLNIAKIVLSIIENDLQTSLPKDEVKFISMFLN
                     SMYLEPNNQSESIGVIILAHGNSTASSMCDVANSLLGTNHCNAIDMPLDVKVSTILDK
                     TIELVKECDEGKGVLLLTDMGSLIAFGELISEKTKIKTRSIEMVSTPIVLEAVRKSTL
                     PEMTLDELANSLSSLNPYIGRAAIDSTEINYPEKSREYVIITTCITGYGSAMKVADFI
                     NSSLKNISKYNINLVPHNIESFKMYKNKFSNTKILAVVGSVDFNVANTPFIHIEELLN
                     GYGLDMLNKIIEGTFNANSITNIKETNLSYNSLIINFMTQNLELLDSVKLFNYVNSSL
                     FTIIELIDENLKSKFKLGYILHCSFMIERCFKNTTFPYNNITELISKNHELYSLIREA
                     FKPTEAYFNILIPDEEIAYIIDMINEYLNK"
     gene            36427..37671
                     /locus_tag="KRH23_002454"
     CDS             36427..37671
                     /locus_tag="KRH23_002454"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase family
                     protein"
                     /protein_id="HHS5225732.1"
                     /translation="MEDEILKGKIKQLTILALIFIFITPVFAFADTPPVPNSSRAALL
                     IDQETKRILFEKNIDEKMPLASLSKMMTFLLAIEAVDKNQVKETDMVKIDKSTASVGG
                     STCKLKDGDEISLGELMQGLMLVSGNDAAIAIAKHIGKTEKNFVNMMNKKAEEIGMID
                     TYYFNPNGLPIYTDPEHKEPPIENMSTAHDIVTLGKYMYDHYENQVTRITTMQVYNDT
                     KKDFTHYNTNPLLVSVPGVDGIKTGYTDNAGYCLAFSMMVPKDAKNERNHRLIGVVLG
                     DGNKKNRISSSATLLKYGKDNFHSKKIAHKGDIIETPCVDGIDDFKITVKVDKDLYGV
                     VSDNENINPKVVFKNMNYPIHKGDIVGVAKYYNDSGKFVGSVDVKSESNIGCIPLKDK
                     IKIKVAKINKKLEIKNSVCFKA"
     gene            complement(38166..>38402)
                     /locus_tag="KRH23_002455"
     CDS             complement(38166..>38402)
                     /locus_tag="KRH23_002455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5225733.1"
                     /translation="GDSSANTITITVSGTASQAVQTDLDNISVLVKAGAVSETTATDS
                     AANATFEVKKHASDPISTIGKISSGLSSLFNILK"
BASE COUNT        12921 a         6405 c         4481 g        14595 t
ORIGIN      
        1 tataatttat actttgaaaa taaaataaac tatctttcaa acattttatt atatgcttaa
       61 aagatagttt tgtgtcttta aaataaatta aattgtatat attccttcac ataacttttg
      121 tatattacta ggtggttgcc atttaccatc ttttttagta tatgtaatca tagttgtaac
      181 ttccttagtt ggtttcttat tgtaaaggtc tataatcatt tttgtcatat cgtcttgaac
      241 ttctttttct tttttatcgt aattcttttc atcagttaca taagatttta ctaaagtgtt
      301 cgcttcactc attactttac tagtatctaa agctttactt acaactttca aagttatctt
      361 atccttacta gaagattcca ctgttactgt cttttcaaca ccttgaatta atttaacaat
      421 tgtttcgtat atcttttcag cattttcttt accataaaga ggtgtcaatt gagcaatcat
      481 tgaaaccttg tccttgctgt tataagtttg aatctgttta tattcagctt ctgttaatgc
      541 atcagaaatt cctttttcat catacttata catttctaat gcagctaaat tagcttcaaa
      601 attcgacttt actttttctt ctgcattaga acaccctata gttagaacta aaactagagc
      661 cataatcgta gataatatta acttttttac cattttcata caaacatcct ccctcaatta
      721 aaataataaa aaatttattt atcaacatta taacataaat ttgtctaact atagaattat
      781 tttgaatatt ttaccacttc cagtctattc caataccgtt ttcttttgct ttatcgtata
      841 ttctttttgc tgttacgaca tcttgtacac ctatcccaac agttttaaat acaattatct
      901 catcatcatc ttctcttcca ggaatagttc cgtttataac attccctaaa tcaccactaa
      961 aatcatcttt acttatctta ccttctttta atggaattaa tatatctcct gactcagata
     1021 aaactgcatc tgttgattca aaaaatatct tagacgctct agttaaacag tttgggcaca
     1081 actcttgcat atctggcata tatgaaccta ctgcacttat taaagctcct tttttcacta
     1141 agtttccatt aagtactggt tgttttgatg gagtagctaa aactatcaca tctgcgttat
     1201 ctatggcttc atcagatgat tcaactgcaa ctattttagt attatattta cttaatttta
     1261 agttcatttc ttctgcaaat ttttctctac tttccttgtt tctactaaaa actcttacct
     1321 catccaaatt tctagcttct atcatggctt caagttgtgg ctcaccttgt cctcctagac
     1381 ctatcaaagc tccaatctta gaatcttttt tagccaatac atctatagct gctccagagg
     1441 ctgctccagt acgaatctga gttacataag taccatccaa tactgcacta acttctccag
     1501 tttctccatc taataatagt actgctgctg gaattactgg tttgcctttt tgagcatttt
     1561 taggaaatac agatacaatt tttattcccc cacaacctaa ttcttccaca tatcctggca
     1621 taaataacat actagcatct tgacttggaa cagatatatt ggttctcaaa ggatttacac
     1681 tctttccttc acaataaatt ctaaaagctt ccttatcagc ttcaattgca tctctcattg
     1741 taaatacttt ttttatgtcg tcttttttta aaagtagcat ttttataccc ccaattttaa
     1801 taagtctcta tgctaaatat tatagcataa catttaattt aatcttctat ttcaaatcaa
     1861 ataaatctac atactctggt tttagcatag aacttatcaa cgctttattt attgaaaatt
     1921 ctggtattcc tgctgcatat ggagttatat catataaatc aaaatataca actagattct
     1981 catcttgcaa gtaaaagttt tgattctctt ttataccttt aaaattatat attccgatat
     2041 tttcttcatc ctttttttca agttcagcta tttgtctttt aatttcttca tctataactt
     2101 ctttatattt agtattatcc ttaaataaat ccattaattc taaaaatttt ccagttctca
     2161 tatccacatt atatgctaca tcttgataaa atccatgtgc tccaccacta taagtataat
     2221 atctcacttt tatactaaga gcagaatcag tattcttttt aagttcaaag tctacatttg
     2281 caacaaactt atttttctcg tcaggattat ccttaagata ctgctttgct tctttatatg
     2341 atttattata aaattcaaat atgtcatttt ttatcttatc atttgtagac ctttcaacaa
     2401 ttttatttga atttgttatt acaggcatgt ttatagtact ttctaaatac tcatcatttt
     2461 tcactattgt tttacttcct attgtactta ctgataaagt ttgtttacta tttgtattac
     2521 cctttggtaa tgactggtta ctcataacag tcactgcttc cttattacta tttaaattaa
     2581 ttgaagcatc tttccttaaa ttattatatt tatagtcatg tttaattgcc aaaacagcca
     2641 ttatagtcaa tgttaaaaca aatacatatc ttaaaacttt agcttttgta tcgactttaa
     2701 aaaatttcat attatcattt tcctcctaaa tataaatctc tcttattata tttggagttt
     2761 ctagggtttt ttatccatat aatttaataa aagattaatt tttatttata aaaaattaat
     2821 ctttttgttt taaaatatta atatgtctta tcaaacagtt tgaaatttca ccaagaggta
     2881 attgtaacat aacagaacct ctatcaaaag ctaccattgg cattccatat actatacaag
     2941 aattttcatc ctgtccaatt gtaaatgaac cattttcttt catttttaaa agtccatttg
     3001 ctccatcata acccatacct gtaagtatta ttcctattga atttttacct gctacttctg
     3061 ctactgaatc aaacaaaacg tctactgatg gacagtgacc acttattctt tctccttttt
     3121 cacaagttac ataatatcct tgtttatccg tacacaattt catctggtaa cccccaggtg
     3181 caattaacac atttccttgt tcgactctat cattattctt agcttctctt acattcataa
     3241 tacactgctt gtcaagccgt tgtgcataca tataagtaaa tatagctggc atatgttgaa
     3301 ctacaacaat ccctggtgtt gattttggta ggtcttttat aatttcaagt attgcttctg
     3361 taccacctac agatgcgcct atagcaataa ccatattatt aaaacgttcc atattaccgc
     3421 ctccaaaaaa tcatatatca aaaatacctt tttatcgttt atatatagca ggttttacat
     3481 atttgtattt agtactactt ctgttgatta cttctgcatg tcctacaaac aaaaaactat
     3541 cttttttggt agcattataa aatttattta taagttcttc tcttgttttt aaatcaaaat
     3601 aaatcataac atttctacaa aaaatcaaat caaaatgttg atatgagaaa tcattcatta
     3661 aattaaacgg cttaaaaatt acactttttc taatcttatc acaaatttta aatgtaccat
     3721 ccttgttgtc tataaaatac ttcttcttcc ataactcagg aacattgtta acatttgatt
     3781 ctatgtatat acctctttta gctttttcaa gtgagttagt tgaaatatct gtggctatga
     3841 ttttaatgtt ccacaactct ttattatatc caaaataatc atccaaagtc atagctattg
     3901 aatacgcttc ttctccacta gaacatcctg cactccatat atttatgttt cttattttat
     3961 tattttcttc ccaaaaggga agtatactat tctgtataaa ctcaaaatgt tgaggttctc
     4021 tcataaaaaa tgtgtggtta gtactcaatc tatttattag gtttatagct tcatttcctg
     4081 tcttatcttt aaataataga ttcatatatt gactaaaaga actaagtttt ttctctatca
     4141 ttgtattgta taagcgacct tcaattaacg ctcttttttt acttaaatca ataccatatt
     4201 ctttttttac atggtttaca agaactataa attcttcatc tgtgagtttt atcatgcaaa
     4261 aacttcctcc tgctaattta tcagaactaa ctacatgcta ttaatcaaaa actttcgaat
     4321 atctaaaatt aatatagaat tatcttcaac tttcgcaatc tcttttatat ctttattaat
     4381 attagtgttg ttagaattag tcgtctctag taaatttaga ttttctatat gaataacatc
     4441 aacaacttta tctacaataa ttccaacttg atactcatca acctttgtaa ttattataca
     4501 agttctctca ttataatcag ctttaggaag attgtacttt atatgcatat taataactgg
     4561 tattattctt cctctcaaat taataactcc acttatatat gttggaagac atggtacata
     4621 cgttattgat tgaaatctta tggtttcaat cacattttct aattctattc cataaataac
     4681 atcattgaca taaaatgtta atacttgttt aataatttca tctttagcca tactttaaat
     4741 cccctaatat atttctataa tgctatctgc atctataatt aaacttatac ttccatcccc
     4801 aagtattgta catcccgata aacccttatt ttttatatta aatcggttaa aataaactgg
     4861 aaatggtttc acaacaactt gctgattacc tattatttca tcaacaaaaa tgcatactgc
     4921 tttatgctca ttttcaataa ttatcatatt accattcatc agattggtta cttttgtttg
     4981 aatattatat attttatgta accttataat gggaatacag gctccatata ttgtaattaa
     5041 ctctgtctta tttccttctg taattatttg atttaagtct gtaagtttaa atgttcttct
     5101 tatggatgat attggtaaag taaatagtga atctccaact ttaaacttca taccctctac
     5161 tatagaaaga gttaatggta tttttatagt aaaggttgtc ccttcatcct gtttactttt
     5221 tacttcaatt gaacctccaa ctttttcaat acttttacga acaatgtcca tgcctactcc
     5281 tcttccagaa aattcagtta tagattcttt tgtagaaaaa cctggagtca taatcaaaga
     5341 attgacctcg tcatcagtat actcattact ttgatgttta agaagacctt gttccttagc
     5401 ttttgccaaa atcttatctc tcataatgcc tctaccatca tctgaaatac ttatcacagc
     5461 ttctccgcct agattctcag cagataaaac tatctttccc acttcttctt tacctttcgc
     5521 tatacgctcc tcaataggct ctattgcatg gtccatagca tttcttataa ggtgcataaa
     5581 aggttccgct aaattatcaa ttacactctt atctacctct gtctctgctc ctatagttat
     5641 taactctaca tttttatcta attttttatt catatctcgt acaattctat gcattttttg
     5701 aaatacacca gcaatttgaa tcatacgcat agacattact atatcttgca attcatctgt
     5761 aagcttgtgt aattgtcttg ttgccttatt gaaattatct atatcaacac ctgtagaatt
     5821 tacgctattt acaaccattg attccataat tacaatttct ccaactatat tttgaagtaa
     5881 gtccaatttt tctaaattta cactcataat actctgctta cttattggta aatgttcatt
     5941 ttcttcactt agactatctt tttccatatc agttttttca tttaaaacat cttcttgtat
     6001 ctcatcttct gtatagttat tttgataact tttacttact ttattattat cttttaattt
     6061 attttctact gcatcattgt ttgatgtatt tttcatttct atttcttttt tactaatatt
     6121 tatgtattct tttacataga gattatcttc tatagtttta taaactattg ccttatcctc
     6181 tttagctaca aattgtatat aaaacccata acttttaata tactctgtag actctgcatt
     6241 tgtttctaca tcttttggat aaaaatctat aaattcacag taatctctaa gttcaaatac
     6301 aagcatgaaa gctctcacat tttccatcat gcaaccttgt tcaaagatta tttttactac
     6361 atcagagtct tctttgtatt caaaatttga atcgattact tctttttcgt ctttactttc
     6421 taaatttgca ttatcctttg atttcataga acttgataat tccaaagtac tcacatactc
     6481 ttcaattcct tcaataaaat tagagtaatc agaagatata caacctcttg attgtaactc
     6541 atctatatct cttcttataa aatctaatga ttgaaagact aaatcaaata ataggtcatt
     6601 gtctaaaact tctattttac cttcacgtat agcataaaac aagtcttcta cactatgtgc
     6661 taaagcagat atattgtcta accccatcat agatgctgaa ccttttatcg tatgcattat
     6721 tctaaaagtt tcattaatgt tgttatgagt aaatactttc tctttttcta tttgaatcat
     6781 aatttcatct aattgttcga gtaataaact tgtctcaaat ataaacatat ctaacatttg
     6841 tctcatactc ggttcaatat aattcacatt tatcacctac gacctacaaa taattttcta
     6901 ttatatatgc atctcataat ttaaatcctt gatgattctc ttatctcact atatgtacct
     6961 cataatttaa atacacaatc attctcttat ttcaatatat atacatctca taatttaaat
     7021 acatgataat tctcttactt caatatatat acatctcata atttaaatac atgataattc
     7081 tcttatttca atatatatac atctcataat ttaaacccat gatgattctc ttacttcact
     7141 ttcctttaga tgaaattttt ctactaattc ttttaaaatt tgagcttgag cagacatctc
     7201 ttctgaggct gctgcacttt cctctgctgt tgctgagttc atttggacta ctatggaaat
     7261 ttgctctatt ccagataaaa tctgtgtaat tgctacttct tgactatgta cagccgaaga
     7321 aataccatta atataattag tagttttttc tacaccattt actaccaagt ccaatgcatt
     7381 tgcagtctct ttagcaattc tgacaccatt ttctactgtt ttaatagctt cttctatgag
     7441 aatagctgta ttttgagctg cttttgcact tttaccagcc aaagacctaa cttcatctgc
     7501 tacaactgca aatcctctac catattgacc tgctcttgct gcttcaacag ctgcatttaa
     7561 tgcaagaata ttagtttgga atgctatctc atctattgtt ttgattattt ttgatatttc
     7621 actcgatttt tcacttattt cacccattga tgtcatcata tcatccatac atctacttcc
     7681 gaaaccaact tgtgatgcag attggtcaga tacctcacat gcaagactag cactatctgc
     7741 acacttctta attccatctg atatctcatt aatcgtggaa gctaattctt ctactgaact
     7801 agcttgttca gtagcaccct gtgaaagagc ttgtgcacct gctgcaactt gttctgaagc
     7861 acttgcaact tgttctgctg ataaatttat ttcagaaaaa tcaccattaa aagagtttat
     7921 tatactttct aaagatattt taattgattt aaaatcacct ataaattctt ggtctatctc
     7981 tactcttaaa tctccttttg caatactagt taatgtactg tctataaggt ctatgtaatt
     8041 taaaagcata ctttgcatct ttttgacaga actcactaat agccctattt cagatttact
     8101 ttcttcaacg tctatacttg ttcttaagtc cccagatgca attcttgaaa agtgtttttc
     8161 tactttatta ataggaatca ctatttttaa ttttattact gtatattcta ttattgtcaa
     8221 tattattaaa agggaaagta taaatattgt tcttaatatt agactttgta attctttttt
     8281 tacttctaca attttggaat ttgaacgggt aactatatcc tcttgaaatt catttattaa
     8341 agaatccatt ttctcttggg agtttatata gtcactacca aaaattatac tttgagcttt
     8401 actcttatca ttactttcga ctgcctttat tgcactttgt tctgttggta ctaaagaatc
     8461 tgatatttct tttgcttcta agattttatt tgactcgctc tttgtaagac caattttttc
     8521 taatttgttt aaagctgatt ctcttgtttt tccgtataat tctttttcat aaatatcttt
     8581 attctttttt tctcctgtaa atacatatct tcttaataca tcacttatct ctctagttgt
     8641 atcttttata tactgacttt gagtcctcaa attattcata tcattaatac ttttttctac
     8701 tttttcaaat gctttataag atgaaataga agaaaaaatc cctgctagaa cagccaatac
     8761 tataataatc agcaatacaa ttgctaattt agaaagcttt acttctcttt tcatatctgt
     8821 actccttcat aaagtaagtt tatatctttt ttaatccttt cattgtactc actacgctac
     8881 aatcttttcc taagttttta ccctcataca ttgctttatc tgctaaggat atgttttctt
     8941 ctaatgatat atttgagttt acttctacta ctcctaatgt aatagtacac tttattttat
     9001 gttctttata gttgaaatca aactccttta tctctttacg gattctttct gaaagtatct
     9061 tagcaccttc tattggagta tttgtgagca ttatcaaaaa ctcttctcca ccccatcttg
     9121 atacagtatc aatttgtcta caattctttt ttattatact tgatattact gttaacacga
     9181 aatcccctgc ttcatgccca taagtatcat tgataacctt aaagtcatca atatcaccaa
     9241 ggataaggga tattgatgtt tcactatatt tattaattct tctttgctcc ataagctgat
     9301 taattatatg tcgcctattg taaagacctg taagataatc tcttacaacg agtctattca
     9361 atttttcaag agaagattcc agttcattat ttatcttttt taatttatct tgagatttct
     9421 ttacttcaag atgagctata acacgagctt ttaattctgt catactaaaa ggtttcacca
     9481 tatagtcaat tgctcctaca ccaaatcctt ttactatgtc tgtatctgta ttttttgaag
     9541 ttataaaaat tataggtata tctgctgtac gagcattaga ttttacttcc ttacaaaact
     9601 caaaaccaga gttatctggt aaaattatat caagcaaaat aatgtctggt ataaattctt
     9661 caataaattc ttttgcctct attgcattaa atgctttttt aaccttaaaa ttatcttttg
     9721 taagtgtttt atctattaag tcacacatca gaacactatc atcaacgact aaaattgttc
     9781 cctgttgctt atttttcata tacaaacctc tcttaaacat aatatattca aattttaatg
     9841 atttaaaatt tttatactta ataattatac cactatattc ttaaatgttc tcatcacaat
     9901 ctttttataa taacactcca actacatccc tatattacat gatagtgcaa tcaaacccat
     9961 tgattaattc atctattaaa acttcatctt tatctgtcaa aagtttctct aaatctagta
    10021 aagtaattat tttaccttct aattctccaa ctccacttac aaaataatcc gaatattcta
    10081 tagtaactct tggtggaggt gatattttac ttttttctaa gcttactata tcatcaactc
    10141 tatcaaccac aaatccaact accaagtcct ttatttcagt tactactata tacatgcaat
    10201 ttgtagtcat taattcatct tttttaagtc tcaaacgcat atctattatc ggaatgattt
    10261 ttcctcttag atttattatg cctttagaat atgtaggtag ttctggaata aatataattt
    10321 cttgatttcc agtaatttct attacctttt caagttcaac cccaaagtct tgctcatcta
    10381 ctctaaactt tagatactta attccttcat caattagtcc ataatctaaa tatgggtcat
    10441 ctggaaatct catttaatac ctccctccta aaatacactt tctatgaaat atatattata
    10501 atttcttctt acctttattt attgaatcta caagtaattc acccgtctca gtgtaaaaac
    10561 gtattgttct accataattc atacctgtgt cctcagctaa tattggaata tttaatccta
    10621 aaagagtttt ttttactgcc tcaacattcc tatgtcctat acttgcaatt actgaattgc
    10681 tacttcctaa aaacatctga gcacctccag caatttttgc ttttatatat attctatttg
    10741 cacctatatt ctccatagat ttaatgagct catttattcc tgtgtcagca aatttacact
    10801 tattttcaat gttaatagca tctttactat atggcaacat aacgtgtaac attccaccaa
    10861 ttccagctac tttatctatc aaacatactc ctacacaaga accaagtgca taagtaacta
    10921 aaacatttgg tctataggct atcttcatat ctgcaatgtt cactactatc tctctattca
    10981 tacttctaat cccaacctca cgagtatttc tctaagtgag ctcatttctg gaatcatcaa
    11041 aatgtggcta gtaaaataat tatcactcat tttaaattta ttttctataa ataagacttt
    11101 gtcaccaaca tctgaaaatc ttatcatagg cacatttaga acagctccaa ccatatcaat
    11161 acatatatct ggaattgaaa cacttatagt catgtttaac atagatgcaa tagcatttac
    11221 atatgaactt gccataatat ttcctatttc cttaattgct gaaatttcaa ttgcctcaat
    11281 ctcatctaaa aaagcttctt ctttattaaa aagagaactt agcataagtt gagttattga
    11341 ttcatccaac aaaaacataa acattccatt gatatcacct ttcatatcga gtaaaataca
    11401 tactactttg ttttctggac caccaagcaa atttgtcgct tcattatatt caagtatctt
    11461 gaccataggt attaatactt ctacattgct atttatcatg gatgcaagtg cagtaattgc
    11521 attcccagag cctatattac caatttctct aagagcatct atatgaacat catcaagttc
    11581 taaataattt ataatataaa cccctccctt tattattgca tttatttgct tttcattgta
    11641 ttagtgtata tttacacttt tattttaaaa cattatttac aactttaact aatgtttctg
    11701 ttttgaaggg cttcactata aaatctaacg ctccaagttt tatagcttct acaatcatat
    11761 tctcttgtcc tattgcagag cacattacaa ccttagcact tgaatccaac ttttttattt
    11821 ctcttagcac ctctaaacca tctttttttg gcattgtaat atcaagcaac atcaaatcag
    11881 gcttttcata tttaaatata ttacacgctt cttctccatc atttgcttct attaaattat
    11941 tatagccact tttactcaga gcttctttaa ttatcattct cataaaaata gcatcatcta
    12001 ctatcaaaat tttattttcc ataaaactaa ctcctccata tgtacaacaa taaacgcttt
    12061 tatcttcagt tattgtctat actatctgac tatttttcgc tacacaataa atacatttca
    12121 ttgataaata aaagtaatta tttatgccat attatactta attctcttaa cataatttgt
    12181 caacaaaaaa acttatatat ctattgtaat atatgtttgg cgttttgacg agttattaaa
    12241 aatataattg tataaaacat aaaaagttat caaaagtaat taaattataa taaaacaact
    12301 ttataccttt tttatgtttg tataaaaaaa tttttcagat tcattaaaat catttctgta
    12361 gattcatata ggatttgact ttctcaatat ctaatagata gttgtttatt tacttaatta
    12421 tatttctcta tatgtattat cgattaaatt agatttagct ttatacatta ttttttatat
    12481 ttttcaaatt gtatacccat aaatccagaa gtatgctaat gtgtttataa tacttttttt
    12541 catattttaa attaaataac aaatcattat atttacaagt atcatttatc aataaacaat
    12601 attaaatgaa gaatatgtct gaagattcaa agtgatactg atactattaa ttactaaaaa
    12661 agcagtaaat cttttacaga tttactgctt atagttataa ataataaaac tatctataat
    12721 aaatgtacta tactcaatac ttcattcaat atagtaataa caaatctact ttattcctat
    12781 gtaaatatga atttcttgtt tctttgtatc aaaagtatta cattgatact cttcaaaatc
    12841 acttatataa gtcctatcaa aatccatttg ccaaaactca aaccaaaaat ctcctacttc
    12901 tttttgacct cctactataa caaactttgc atacttacct gctggtataa ctttactaat
    12961 aatactttct ccaacagtat tattagtgtt taattcttct aaattcttct ctttatcaga
    13021 attactattt acttcacaac atgcaacaaa gctatacgga cttgtaaaat caccctggta
    13081 atctgtatat agacctattg tcttgtcatt ctttttaccc tttatagcat tatatatccc
    13141 tttgcccata aattttttcc acaattcacc tatatcattt accgcttgtc catctttatt
    13201 tgtagtctcc ttcgatattc ctataactat tttctcattt atctctacta tttcataatt
    13261 catactttat acctcacttt gtttttatta atatatttta tttttaacta attcaattat
    13321 aatttataat atacgacacc tttatgtcat atttttaata taattaaact cagtgagata
    13381 ttatatacta aatgcaagat attatatatt taataaaatc tttaatctag cattatatta
    13441 taatgaataa attttagaca actcccttag tctagttatt acattatccc taacatcttt
    13501 aggttcaagt acttcaacat tgtcaccaaa tgataaaata tatccataaa tccattcacc
    13561 aataggaaat tctgtaatta catcatatgt atcatcttca tttttagtta ttaaatcctt
    13621 attaaaatca tcaaatactc taaaaagcat cttttcttta aacctcaatt tcaacgttat
    13681 agtattttcc ttaattactt tagaatcatt caaacatact tcttctatta tctttcttga
    13741 aaatacttca tcctttatag ataaattcct tatcctacta attctaaata tcctaaaatc
    13801 atcttttagt ttacaaaatc catacaagta ccaagtctta ctcttataca taagcttcag
    13861 tggttcgaca gttctgtttg tctggcttga caaactattt acataattaa aatttatagt
    13921 attacgcctt aaaatagctt cttttatttt tgtaaattta tcatcttcat taaaattact
    13981 tccccattca gtaaagtcta tttcaatcca gtttgaaaaa ttctgctctc caaatattga
    14041 gccaatttta tttactactg aatttatttc tggatactta gtcgcctgta atgttttcag
    14101 tgccactatt aaactctctt tatctttttt tgacaatata gccttgtcta tagaatattc
    14161 ttctattaaa gatatccctc ctcctttgcc tttcgtcata tatactggta ctcccgacat
    14221 agacagagtt tctatatctc tatatatggt tcttgtagaa acttcaaacc tatctgccaa
    14281 ctctttagct gttactaatt ttttatttaa tagaattact attatttctg ttaatctatt
    14341 tattttcatt cattaccacc tactaaaatt attaaattta tttaatctaa attaatcata
    14401 ctaattttta aataaataaa atcttagaat cttatctaaa ttattcttac atgattttat
    14461 ttactttcta ttatctttct cactttggat attatcatct taatttattt attactatat
    14521 caatttactt attatcatct catttgttat cgtcttactt aatttactta tttctatatc
    14581 aattcactta ttatcatctt aattcatttg attattatca tttactttat tcaatttcta
    14641 tatcaaaaat tagtatttgt acttaatact taaaattaat ttgaagtctt tacatattat
    14701 ttatttttta ttgtaatatt catttccata ctttactaag ctacttccac tcatttattt
    14761 taaaatttca atttactatt tctcaattct atattattat ttttcaattt tatattacta
    14821 attttaaagc tttttagcta ttattcctac aatatttaaa caattttttc ataataaagc
    14881 tatattacaa tatattcaaa atatgtaata ttttagatat ttttcgttga caatgttaaa
    14941 tttttgtttt atccttaatt aaggacatgt tattgacatt tctgaaactt atttgaaata
    15001 gttttttcat tttatttagg aaaacgtatt atacttaaga aaacgtattt tctcatttca
    15061 gataagtaaa atatttattc ttttggggag gaaatcatgg aaattaataa aaaacatttt
    15121 attcaagtat ttttaacttg cttaatcttg gtagtaatat gtgaatttat agggcaaaga
    15181 actatagcta ttggaaaagc ctctatagta ctgttcccta tgctttatgc agttataatt
    15241 ggacttataa taacaccaga tttattaggt aaaaaaatta aagcacttaa aaaagtggtt
    15301 ggagaaaaag aaataaatat tgctggtgaa gttgttggaa ttgcactagt aatgcttggt
    15361 ataaaatatg gtactacagt tggaccaaac attgacaaaa taattcaagc tggaccagca
    15421 tttatcgctc aagaatttgg tcatatactt gcaccaatcg ttgcattacc tcttgcatta
    15481 atgtttggaa tgaaaagaga agctgttgga gctactgcaa gtataagtcg tgaaccttct
    15541 ttaggagtta tatcagaaaa atatgggata aactcaccag aaggtagtgg tgtacttggt
    15601 acatatttaa tgggaacagt tcttggtact atatacttta gtgtactagg ttcaatatct
    15661 atttatagtg gtattcaccc atatgctttg ggaatggcct gtggtgttgg tagtggaagt
    15721 atgatgacag cagctgctgg ttcattatct accatggtac cacctgaaat ggcagataca
    15781 atacttgcct atgctgcaac aagcaatatg atgtctagta taacaggaat tatattctta
    15841 gtttttgtat ccttaccatt tactaatttt atgtataaga ttttagaacc aaaattttcg
    15901 agaaataaaa aaactaaaga aattaaatct acagaaggag agtgctaata aatgtttgct
    15961 aatttaaatt taaagaaaag ttcatatcaa ttattggtta tgtctgttat tggagttata
    16021 attcttatag gacaaagaat tagcgttggt acatctatag ttacagctct tcctggtatg
    16081 gtgatgctaa tattagctgc tatggcagct atgattataa aagatttatt tcctaaatca
    16141 atctttccag cttttggatt tgcaactata atcggccttt tacttagtat gccatatagt
    16201 ccaacatctg aagtattctt aactaacact aataatatta actttatggc tataactact
    16261 ccactactag cttttgcagg aatttctgtt ggaaacaaaa tagaagcttt aaaagaaatg
    16321 tcatggaaaa tagttataat ttcacttatt gtatttacaa ctatattctt tgcatgtgcg
    16381 agtatagctc atatagtttt aagtattcaa ggtaaaatat aggaggaatt tattatgaat
    16441 aaagaacaat taaaatctct agtaataaaa actatagatg aaaatagaga aaaaatatta
    16501 aaaataggtc aaggaatata caaaaatcca gaatatggat ataaagaatt taaaactaca
    16561 gaaactgttt caaacttttt tgagcaagaa ttaaatttat ctgtagaaaa aaatatagca
    16621 gttacaggat gcaaagcaga tgcaaattct agcaagaaag gtcctcatat atctatactt
    16681 ggagaattgg atggtatatc atgtaaagaa cataaagatg ctaatgaaat aggtgcttct
    16741 catacttgtg gacataatat tcaaatagct ggaatgttag gtgctgctgt tggtttagta
    16801 aaaagtggcg ttttagaaca tttagatggt aaagtatctt ttatggctac tcctgctgaa
    16861 gagtttattg agttggaata cagagagcaa ttaaaaaaag aaggaaaaat aacttatttt
    16921 ggtggaaaac aagaattaat aaaaagaggt tattttgatg atatagacat atctatgatg
    16981 tttcatgctt ctgatttagg agaagataag gctctagttg gtcctgagag taatggattt
    17041 gttggaaaaa aggttaaatt tataggtaaa gaatctcatg ctggttctgc tccacatgat
    17101 ggaataaatg ctttaaatgc agcaatgctt gctataaaca acgtgaatgc acttagagaa
    17161 acttttaaag agtctgaaag agttagattc caccctatca tcacaaaagg tggagatata
    17221 gtaaatgttg ttcctgctga tgttcatatg gaatcatatg ttagagctag aactataaat
    17281 ggtatgattg atgctaatga aagaataaat aaggctttga tggctggtgg aatggcagtt
    17341 ggagctgatg ttgagataac tgaaattcct ggatatcttc caatattacg atataaaagt
    17401 cttgataatt tatttaaaaa caatcttgaa gatttaggtc taaaaggaaa agttattgat
    17461 ggtggagatt ttacaggctc ttttgatttt ggagatgtgt ctcatataat gcctactctt
    17521 caccctatga ttggtggtgt aaaaggagct cttcatacaa gagattttga aatagttgat
    17581 gaagatttag cttacataat tcctgctaaa gcaatggcac ttacagttgt agaccttctt
    17641 tttgataatg ctaaggatgc taaagatata ttagatacct ttactccagt tatgactaaa
    17701 gaagaatatc taacattctt agaaaaacac gataaaactt tataagtcta tttttataat
    17761 agggtggtat ctactgtaaa agttatacca ctctttgttt ttgtaacact atacttcttt
    17821 tcttttagtt tttagattaa actaaaatat attatcctcc ttaaaacttt tagagctacg
    17881 ttgaaatatc agtagaacta tgctatattc tttctaatta atataaattt ctattctaat
    17941 tcaaggtggt gaaaaaatgt ttaatgcagg aaatcgaatt ataaatacat ggttgtaccc
    18001 tattcaagat ggctttgtct tgattgatac tggatatgaa aatggtttta aacatttcaa
    18061 aaaacgaatt tctaaattca acataaaaat caaagatatt cgatacatat ttctaactca
    18121 tgctcatgat gaccatgttg gttttctaaa tcagattcta gacgaatctc ctaatacaaa
    18181 gattgttatg catgataaag ctttagaaat tctatataaa ggtcaaaact cttttattgg
    18241 tggttgtacc agccgtactg cctttctctt ttgccaaatt atgaaactat ttggaaaagg
    18301 tgagcatagt ttttctccac ttaaacaaga atttgaaaaa aggtgtattc ttgtgtctga
    18361 caagaatcgt aaagaaattg aaaaagaact aaatggaaaa attatagata caccaggaca
    18421 tactgctgat tcaatttcac tactaattga tgatggtgtt ttattttgtg gagattctgc
    18481 aatgaatgga tttccaagta ctcacaaaat taccatattt gcagaaagca aactagaatt
    18541 tattcaatct tggaaaacaa tcatcaatac aaaacctaaa atgatttatc ctggacatgg
    18601 aaaaccattt gaatacagta aattagaaca aaatctaatc tatgtaaata aaataaattt
    18661 atatcctcta cataattcaa aagatattca cagatttttg tagaaaatac aaagtaaatt
    18721 tctttgatta attaaaaacc taacacttta ctacgctact tattttaata acttaatctt
    18781 ccactagctt ttcataaaat tttgttttaa aattaatttt aaagtgcata tgttatttaa
    18841 atacattaga tataattcgt cattaatcta cttaaagcat atttaactaa caccactcaa
    18901 ccagaaaatt cagaaaactg cattgacaca ggaaaaagtt tattttatac tttttttagg
    18961 acatattgtg gacacgtctt aaatcgacaa gcagaattta aattgtaaga ttaaccacaa
    19021 tacttatttt ttaattatat ttttaaacat tagggaggat attatgaatg ataacgtagt
    19081 taagaagaaa aacttttttg acaggacatt aaacagaata gaaactgttg gtaataaact
    19141 accagaccca gttacaatat ttttagggtt atgtgtactt ttacttatac tatctagtct
    19201 agttggttct atgggtatat cagtagttca tcctggtact ggagaaacta taaccgctgt
    19261 aaatttattg actgtagaac agcttcaaat tcttttagga aacatagtca gcaatttcca
    19321 agggtttgct cctttgggtc tagttctagt aactatgata ggtgctggtg tatgtgacaa
    19381 aacaggactt atgacagcaa caatcaaagc atcagtaagc aagattcctg aaacaagagt
    19441 aactcttgtt gtaatgacta taggtatgct tgccaatata gcttcagatg caggtacaat
    19501 attatttcca ccattagctg cacttgtata tcttggtgtt ggtagacatc cacttatagg
    19561 tttattttct ggatatgcag cagtctgtct aggatttgcc gcaaacatta tgataagtgt
    19621 caatgatata cttgctgcaa gttttacagt tccagcagct caaatgattg attctggatt
    19681 tcaagccaat gcaacaatga acttattttt tatgatagca tcaacttttg ttctaatact
    19741 tttggcaaca tgggtaacag aaaaaattgt agctcctaga tttggtaaat atgaaggaaa
    19801 tgcagaacta gatgttgatg gaagtcttag tgatgtagaa aagaaagggc ttaaaaaagc
    19861 tggtataagt atattaatat atgtggctat tatagtagct cttagtgtaa tcggtaaaaa
    19921 accattctta gctgacccag aaacaggaga tttactatca aacaatgctc ctcttatgaa
    19981 aggtatggta cctataatag cactagcatt tttcatacct ggtgttgtat acggaaaaac
    20041 tataggtaaa ataaagaagg ataaggatgt agtctctata atggctagtg caatgagtga
    20101 tatgggtgga tatataatac tagcatttgc tgcttcacaa tttttgcaat tattcacaaa
    20161 tagtaattta gggctgatac tagctgtaaa gggcggagaa tttttaaaat cagcaggaat
    20221 aaatggacct ttattgttga taggatttat tatattatcc tgttttataa atttatttat
    20281 aggtagtgca tctgcaaaat gggctattct tgcacctata tttgtaccaa tgtttatgat
    20341 ggttggatac aatccagcac ttactcagat ggcttatcgt ataggtgatt gtataacaaa
    20401 tccacttagc ccattatttc cgtacttccc tattatacta gcattcacaa gaaaatacga
    20461 taaagatgct ggtatgggta ctgtaattgc taatatgtta ccatactcta tatcattctt
    20521 aatagtgtgg actatactat taatattgtt tatggtattt aatattccac taggacctgg
    20581 aatacttcct tcatatagca tgtaatttat ttaaatcttt ctaaaaggag aaataattta
    20641 tgttagataa aaatagactt ataaataatt ttatggatat ggttagaatt gatagcccat
    20701 ctaatcaaga attagaaatg tctaagtggt tggtaaacta cttaaaagaa agaaatatag
    20761 atgccattat agatgatgca ggtgaaaaat atggtggtaa tacaggtaat gtcattgcct
    20821 atataaaagg tgaagaagga agtagaccac tttgtttatg tgcacacatg gaccaagttc
    20881 aaccttgttt aggtgtaaaa ccaatactag atggtaatgt agttagaagt gatggaacta
    20941 ctacacttgg tgcagatgat aaagctggaa tagctgctat acttgaagct ttagaacatg
    21001 ttattacaga aaaaatacca catagagata tttatctttg ttttacaatc tgtgaggaag
    21061 ctggtatgca tggtgtcaaa aactttaatc ctgacaactt gccttgtaaa gatatggtga
    21121 ttttagattc tggtggagct attggttcga tagcatacaa agctcctgct caacaatcta
    21181 taaaaatctc ttttcatgga aagaaagcac atgctggtat agaacctgaa aaagggttaa
    21241 atgctatatt agtagcctct catgcaataa gcaacatgca cataggcaga atagattcat
    21301 tgactacttc aaatataggt aaaatagaag gtggtggagc tacaaacata gtaactgata
    21361 aggttacatt gactgctgaa attaggtctc atatacctga aactttagag tatgagctta
    21421 atcatatgga aaaatgttgt aaggatgctg catctaaatt taatactact tatacttttg
    21481 aacataatat gtcttaccct agttttgaac ttagtagaga tagtcatgtt ttcaagttaa
    21541 gtgaagaagc aataagacaa gttggtgttg ttccaaatcc aatggtaatt ggtggtggaa
    21601 gtgacgcaaa tatattagct aatcttggat ataattgtgc tatattaagt ctaggtatgt
    21661 atgatgtaca cacagttaat gaatatgtaa atatagacga attatatgat actgccaaaa
    21721 tagtttatca tatgattaaa ttataaatat cataatagaa ctctttaaat tataaaaaca
    21781 aaaacctatg tatcttcaac tttataagtt atatattaaa gttgttttac ataggtttta
    21841 gtatttttat aataatttgt tctaattttt ttcataataa gctttaatac tttatatagt
    21901 aatttgttgt agaattttat acaatataat gatttataca gttttataaa atatcttaaa
    21961 acagtatttc agtaatattt tttggtcttc ctccaccaat actagtctct tttgcacata
    22021 ttcgacctaa acctgcattt actattttat ttaatatacg tcttgcactt ctttcactta
    22081 catttagata ctctgctaac tcttttgaat cataaatctt actttttcta ttctcattta
    22141 tagcaataat ttttgcaact gactcacaac tcatcccagt ctttttagat atttcgatta
    22201 ccttttcatc agatagcatc aaagaataat ttaattcatt ttcggaagct aaaggtcctc
    22261 ttatgttttc atcttcatct accaaatata taccaatttc ttttgaatct atggagtgtc
    22321 ttaatgcttt atgtgcatta ttttcagcct gatacgcagt tactccagtg ccaattccta
    22381 tactaagaga aaagcccatg tcttttatct ctctctttag attgaatagc ttatcataat
    22441 tatactcatt atcagctacc cctttatgaa caaatacaac ataatcattt cttccaagta
    22501 aaaataagga accttgaata cttcttacat agtttactac aagcttatcc atatctgatt
    22561 tttttatcat gtcagaataa tagttatcta tcttctcttt ataatctatt aaactcaata
    22621 tttcaacagc aatttgagaa aatcttgcct tacttagagc atattcactc tttaccttgt
    22681 cataactttc tttgattaat tgtatagtag cttgtaaacg aaatacagga tagcctcttt
    22741 cttttaattc attatatact gcaccaaaac cagttaacat tatatccgtc ttattttctt
    22801 caaataattt tatatgccat tctacaagtt cagactctcc tacttccaaa gaaaatggat
    22861 tacaaaatac actcgttgct ttaatatcaa attctttaag tgcatcttcc acaacatatc
    22921 tatcaactac atctatactg aatttatcta attttatatt tgcacttttt attgcccaaa
    22981 atgccttcat tatactcgtc ccacttctcg gtacaaatga atgtggctta cttatctcat
    23041 acttagattt tataaattca taaactgcac atcctgtaaa tataatagca tcacattcgt
    23101 cttcacattt agaaataact tctattgtat ctactacttt ttctcttaca tatattttag
    23161 tctttaaatc actgtctatc tgttttaaat catcctttat cttaaaccca gagtctgagg
    23221 gacctataat acccactatc ataaacttcg ctcctaatcc ataaatatta tactttttaa
    23281 aaattatatc ctcactattt tctacttcta tttaattatt ttgaactact ccatcctacc
    23341 tacatttaga atggaataat tagcttattt ttgataaagt aacttctcaa aatcagcact
    23401 tggaataggc ttacaataat aataaccttg aattaccaca caatctaaac tcactaaaaa
    23461 ttcagcttgt tcttttgtct ctacaccttc tgccactaca tccatatcta aatcttttgc
    23521 catggctata gtgtgcttta aaactatttt ttctctgtct gtgattcctt cctcattaaa
    23581 gaaaccacaa tctatcttta atgtatcaat attaatattt tttaacatat ttaatgaaga
    23641 atatgctgaa ccaaagtcat ccatatttaa aacaatacca tccattctaa ggtcggctat
    23701 tatcttagta aataatttta tatttttaat aaataaactt tctgtaagct ctaattctaa
    23761 aaaagatttt ggtatactat atttatttat taaacttaaa acaatttctt taaaatgtgg
    23821 attatgcaaa tgtaatcttg atacatttac agagatagga actggctctt cacctaaatc
    23881 tatccatttt ctaatcaaag aacatacttg ttcccataca tacatatcta atctgataat
    23941 aaacccattc ttctcaaata gtgaaataaa tttaattgga ggtattatac ctttttctgg
    24001 atgaacccat ctaaccaatg cttctgcacc aacaatttta tttgcattaa gattatactt
    24061 aggttgtaaa tatacatgga attgcccatt ttcaagtgcg tattccattt ccctttccat
    24121 ctgtttttct tcaagtgcat catttcttat agtatcatca taaaatatat agttattgat
    24181 actttgtttc tttacttttt tgtgagcata tcctgccatt tcacacgcat ttgtaattgg
    24241 aatatgatta tccaaaattc tataaacccc aaaacatggt actaacatat attcaaattt
    24301 ttttctattt aagctatttt taatcttata aattacctta tgaatatctc tatcagagta
    24361 actctcataa aaaatgcaaa atacatctgc atacatacga caacatatac cattagaacc
    24421 aatgtttttt tgaatcaact ctgcaacata tattaaagct ttatctcctc ctctaactcc
    24481 ataaatgtca ttaattacct tgaacttatc tatatccatc attataattg cataacgctt
    24541 gtcaggatat cttttaagca ttaaacttat ttgttcacaa aaactttcat aattgtatag
    24601 tcctgttaat gtatcttttt ggtttttatg tagttgcata agataatcta tattttttat
    24661 agcaactaaa atatgtgttt gtttctcacc taacttattt ttactactaa tctttaacat
    24721 ataaattaat gcccaatagt actttttatc tattcctaaa cgtctatact caaaatttag
    24781 ttctaaatcg tcttgcttgc tattattaag actatcaaga gattttagaa ggtggttatc
    24841 attaaataat attatatcat caggatgaat taaatgtttt tttatgtatg aaaaagtttt
    24901 ttcaagattt tcctttatag gaaaactaaa aatattgctc tctgattgat aaattggagt
    24961 aattaaattc gtatcaatgc aaatagataa aattatatca tatgtattat aagctaattt
    25021 ttcataagcc ttagaatacc cttttatcat taaatcatca aaataaacct tatcaactaa
    25081 ctctttatgt ttaaataaaa tattattcgt cgaatcagct aagtcactaa ttactttcat
    25141 ttcattattt ctaagtttgt tcttattata atacctcttc ttatcttggt acattctctc
    25201 atcagcaact ttaattagct tatgtatatc aatattatcg tcactccaaa tactgcccac
    25261 tgctacacta tatatcatct catccttaaa ttcttcactt aaccaactca ctaattcttc
    25321 aaatagttgt tttgatatat cttcacataa tacaacaaac tcatctcctc caatacgata
    25381 aacattataa gaatgaaagt atttttttat tattacacat gctgacacaa tagcagaatc
    25441 gccattagca tgtccaaagt tatcattaat atcttttaac ccatttatat ctacaaatac
    25501 aactcctatg gatttaactt ttcctttttg aaaattatct atatacttaa tatatttatt
    25561 tctattatat gcaccagtca agaagtcata gtagctcata taatttaatt tattttctac
    25621 ttttcttttt ttcatctcag ttaataaaaa ataagatagg gatgtcaaaa gagaggtatc
    25681 tccaacagct ttatgtggat tatcaactcc aataaaccct actactttat catcttgttt
    25741 tagtgaagat gtcattaaac tttcaatttt ttgaggtttt aaaatttcat attctattgg
    25801 ctgttcttct tttatatttt ctatatcatc aattattaca aaaccttttt gttcgaataa
    25861 taaaaaccaa ttctttaatt cattaatatc aagatttgtt agtgcctgtt tttgttcatc
    25921 aacaccttca ttgcaccatt catatgtatt agttactttt gttctatctt ctgatacttc
    25981 aaaaacatat gctctatcag ctttatgaaa tttaccaata ttggttaata caagatttac
    26041 agcatcagaa aaattagatt ctgttataag atgtttaata catccaacta ataactcctt
    26101 tatctctaat ttttctgcta ttgacttact tatatcttcc ttttctgtaa tatcaagagc
    26161 tatttctaat cgtgcatgtt tgccctccca tttaattaac ttgtccttta atataaaatg
    26221 tctatttgtt cgagtattcg tattttccca tatgtaatat tcatcttctt ttaaaataga
    26281 gtttgtacaa aattcgcagg gagaatcttt cccctgtaat gctttataac attttaaatg
    26341 ggatatatca ttaagtccca ttgccttttt cccaatttca ttaatatata aaagttcata
    26401 tgtatctaaa gaagaaacat atacaatttc atccaactca tctattaaat ttattacatc
    26461 catttatata tatctccttt tattcatttt ccagattgaa tttttaaagc ttttaaaatt
    26521 ttgctatata tttggcaatg atattatact tctttatgtt ttaaaatagt accttaatga
    26581 ggttctattt tttagtaaat agaattatta ttgtgtcaat cgtacaatag agttttgtaa
    26641 tacttaattt aatatattta taattaacta tcttattatg tatttacaat taattctcat
    26701 ataaatgaca aatctccacc tcaattaagt attccaatca tatatgagga taatacttca
    26761 ttcatttaaa aatataaaac tattatatat taaaatttct tcaataataa attatttaga
    26821 ttgttacttt gatatattat ataatatcac aaaggctgat ataaaaagac aaaaagggca
    26881 atttttttat atcaaaaaaa atgttaaatt gatattatcc atatataaat tgatattatc
    26941 catatagatg ctatatttaa caattctact tacttccctt acacttatta gcatatagtt
    27001 attaagagtt tgttgcaaaa caacacttag cacactttaa aaagtatggt ctaataagta
    27061 atcaacgaag aagacataat aaagcataaa atatgatata cttttccacg ccatcaaaac
    27121 tgaggatttt attattaata tatgctaaaa tatgcttaat aaattaaatt ttaatgggag
    27181 aatagttatg aaaatattta gtttcttgtt gtttgtgata ggaatatgtt tatgtattgc
    27241 tggatttata ggacattacc cagtatttgt tggtacaaca ttgagttttc ttgcaattgc
    27301 aatgatagct gtaagacaag tcaaaactaa gaaaaaatga aataggcaaa tcctaacttt
    27361 acaagttaat attacataag taattagtct aaaattggat actttttcta ttacagaaat
    27421 acatcatcca ctttgtattt tcttaaaaaa ataaaatagc tatgtaaatt caagattaga
    27481 tagattaact ctctatccat ttcattgtaa aatatacata gctatttgta ttcgatttaa
    27541 aatacttaga ttttcttaca taacaaataa tttctatctg attattactc atattcattt
    27601 agtaatcact cagcaactaa tcatttagta tctattcatc cgccatacgg taacctaccc
    27661 caacctcagt caaaatatat tctggctgag caggattctt ttcaattttc cttcttatac
    27721 ttgccataaa aactctaagc gactgattct cactttcata gtaatttccc caaactttat
    27781 ctattataaa cttatgggtt aagactcttc ctgaatactt agacatcaac tcaataatct
    27841 tatattcgat tggagttaag tgtatttctt caccattaat tgacacaata tgattttcat
    27901 aatctatctt taggttttta acttcaaaag actttggagc atcattattt atattatcct
    27961 gttgagcttt atttctaaga gccacacgta ctctagccaa aagctctgtt acactaaaag
    28021 gtttagttaa ataatcgtct gctcctccat ctaaagcttc caccttatcc ctctcatgct
    28081 ctctcgctga aacaacaatt attttattag tctttgcaca tgccctaact cgtcctatta
    28141 cctcaatccc atcaatatct ggtagtccta aatccaaaat tatcaaatct gggtcaagag
    28201 aatgtataag tgatatagct gttcctccat tatctgtctc tacacaccta taattttgag
    28261 tttcaagaga tacttttata aatttacaaa ttggcttatc atcttctaca attagaacta
    28321 atggctttat ttccacttgt ctttcccctc ctcatcatac ataggtatgc taaatctaaa
    28381 tgtagctcct ccagaaggat tattaaaggc gacaatttct ccaccatgag cttctactat
    28441 agatttacat atctccaatc caagaccaat acctcttctt tcaagatttc tagacttatt
    28501 cttagtataa aacctattaa aaatattccc gatatcttca tttggtattc cttttccatt
    28561 atctgcaact tcaaatagta cttgatttga ctcttttttt acagttagtt ctatcttaga
    28621 atttttaggt gtatgcctta tagcattatc aattagattt actaacactt gttctattaa
    28681 taatacatcc acatgaacga ttattatctc atctggaata tttgttttta tgtatctact
    28741 attggcaaac tttttgactc ttaatataga ttcagctatt atttcatcaa caacctctgg
    28801 tcgtttttca atatccaatt ttccttcatc tattctggtc atactaagta tattctcaac
    28861 agaatgagtt agccaactcg tatcttcata tatatttttc aataattcta ctctagtttc
    28921 tttatctatc acatcatcat tttcaagtat tgttgaagat gaacccaata tacttgtaag
    28981 tggagttctt aaatcatgag aaattgacct aagcaagttt cctcttaacc tctctctctc
    29041 tgcctcaagg tttgcttttt tatttttctc aaataaattt tctctatcaa ttgccaacgc
    29101 aacctgtgtt gaaactgctt ctaatagtat cttttcattt tctgtaataa tatctatctt
    29161 aaaacacgca acacctataa caccaagaac atttgattct tgacctttta tagggaaata
    29221 atatgcactg ctgtttttac aatattttgt cccaattcca actgggttac ctgtcctaaa
    29281 agcttctttt atagcttcct tttctaatac tgaatggaat atattctcac ttccatcatt
    29341 gttacaaata taaatacttg gcttacctag attattattc tcatctgcaa tagtcactat
    29401 tacagttcta tttaatatat ttactaaatt agacccacaa aattcaataa tttgattttt
    29461 attttttgct ttaagcaacg ttttgttatt ctcatagagc aatcttatca ttttttctct
    29521 cttatgagaa agtctcactt ctctttttat cctagaagtt aaagtacttg ttataattgc
    29581 tgccattagc ataatacaaa aggtcatagg ataatctttt ctataagcta aaaaagtata
    29641 taatggatgc gtaaagaaaa aattaaatga tagcactcct attactgaag aaagtattcc
    29701 aaaaaaatat ccataggtta tacttgtagc aaatagtaca cctaatatgt atactagtat
    29761 aatattagat tcattaaaac ctaccttttc aaaaactact gatattccag tagcaattgt
    29821 cataaccaat atagttttta tgaagtcctt aataattatc tttttactga gatagccatc
    29881 ttcatcataa tcatactctt ttaagtcttc atgttgtagt cgttcctttt tcatttacta
    29941 caattcctcc ttattgttac tgtttaaatt ggctctattt tatataatac aattttatca
    30001 taataaattc aatcaataca tttaattaat gtacttaaat tactaaaagg tgctgtctta
    30061 aaatgaaaat aaatctctat ttcaaaacag cacctatata tttaaattac taatttagtt
    30121 tttacatact taaatcaata gttttattca atttcataaa ttataatact tcaattataa
    30181 aacatttcta tccaacaagc ataaatataa agtgggcaca tatacctgca cataaaccac
    30241 ctatagtatg cgaaagtatc gctttaccag ccaatggtct tgcatctaaa gcatccatca
    30301 tacctatgtg tgtacttaaa tatccactcc aacacatacc cattgctgtg aatactgcta
    30361 tatcattagg agttatagcg cctgatttta taaactctgg tactaaagat attgctgctc
    30421 caacagctcc taatgcagtt acagggaatg ctattgcctc tggtgatgtg aatccaaata
    30481 atggttctat tatgaagcta atcttatcac caatagcagg taataatttt ataccttcat
    30541 atgcagctcc tgtgtaaaca gcttgacctg tagcagggtc tgtagatggt ccaaaagtta
    30601 ataacataac taatgtacaa actactaaaa ctcctggtat tatagccata cccatttcaa
    30661 cacctaactt accaccttca agtatagcat ccaatgttct ttggaataca ttaccatctc
    30721 ttatttctct aaactcttca agttttgcac ctttatcatt tatttgcttt tcagtatcat
    30781 ttttagggtc ataattataa tactttttag taaaagtcaa cataattcta acactaataa
    30841 tactacctat tattgccgca acattaccta ttatagctgg tagtacatat tctttacctt
    30901 gagctatcat aaaagttgtt acaataagtc ccataccaaa ggctgttcct aaattacata
    30961 aagcaggtac ttgatacttc ttaaaatatt gtgtaaatgt tttgtcttta gcaaatggta
    31021 taatagctgg attatcagat aaatatgttg caactactcc tgctatacta gcaccaggta
    31081 aaccccatat aggtctcata agacccttaa atatcttatt aactaaagat attactccaa
    31141 actctgaaag caatgcacta agtgcacctg caagaactgc catagccatt attaaaaata
    31201 ctgtgtctaa taaaagcgca tgtgctgtac tcattattac tttaaacatc attcctgcac
    31261 ccatgatgct tcctacatat ccaaatccta ccgccaatag tacaataaat acgaaggttt
    31321 ccatacttac tgccttgact cttctcttat ccgacagctt ttccatcttg aaatcttccc
    31381 ccttttaatt ttaaattaag gttcctaaca ttggtacaaa ttttttggta caaactgagt
    31441 tctaaaactt acactcgtaa tgcaagttgt cagttttttg aaataaaaaa aaattacgtt
    31501 tatagaataa gaatatcctc tttaatttgg atactcttat tctattttat gttattatat
    31561 tatcatcctt ttgtttaaaa gtcaattttt tctatttttg ttgtttaatt ttatttatac
    31621 tctttttata tttttcattt tcttttatct ttgtaagtac tccatataag ttgacttttc
    31681 taaatacagt agttataaat accaatccta atgcaattga acttgcacac gataatgtac
    31741 tcaccccata ttctacagct tttatataat tattggtcaa aacagaatac atagtattat
    31801 atattccata accaggtact aatattatta aacagcaaac acttaatgta gttgctggag
    31861 tcatataaat tcttgcacat aactcacaat atatcgcaaa acaaactgta gctataaaaa
    31921 aacataagtt ttctgttact cccatattta aaagaaattt atacgaaaac caagctatac
    31981 ttccacctat tcctgctagt attaagtttt ttcctttcat attaaatagc actccaaagc
    32041 ttaaggcagt aaaaaaagct gctattactt ctataaacaa atgcacttat atccccccta
    32101 acttgaagta caatccaagt accaagaaca ttcctactgc tatagataca cctacaaaaa
    32161 atacttctgc taattttgca agaccagaaa tcaactgtcc atctaacaaa tctcttaatg
    32221 cgttagtcaa agcaagcccg ggaactaaga gcattattgc tcctgctatt aaatggtcta
    32281 acgtctttat gaatccgagc tttaaaatta aaattgaaca agaagctata ataactgctc
    32341 caattgcatt tacaaaaaag tcattaaggg aagatttact taaatacata ataacaaact
    32401 tagtcagaat cccaacagta aatgcagcta taaattcttc cacatttcct ccaaataata
    32461 tcgaaaaagt tgctgctgca atacctgcaa aaaatattgt tattaaatcc gagtaatagt
    32521 tatcttcact tatttcatct aaaattttct cacataattc aatatctaaa ttatttatac
    32581 ttattgctct tgataatgag ttaacttcat gaaccaagtt taggtctact cttcttgagc
    32641 ttattctttt aattgctgaa tgtaatttcc catctacaaa tacagatgcc attacagctg
    32701 ttggagttgc aaatacatct acgtggtcta ttccaaaaga ttgacatatt ctagctatcg
    32761 tttcttcaac tctataggtt tctcctccac tttgcaacat agctttacct gcatttgagg
    32821 aaaagtttaa aattctatct atatccacaa aacatatctc ccattctttt atagtattat
    32881 tcatatttta atacaagata ttatttattt aaactatttt aaataattca tatccaatat
    32941 ttacatttta tgaaaaaact tgttttttat gcttgtcaaa atcaaatttt aagcttgttt
    33001 acaccataaa atggctgaat taatatttga caaacacttt caaccattta tataaccttc
    33061 taaattgtat aactttttac tacaaataaa attatatctc ttttaattct ttctcttgag
    33121 tatttagctt atagcaactt catatttata tatgtacaat ataaaacatt atttttatga
    33181 tacaaaatat aatttgtaaa tgtatatatg tattaactgt gtatatataa attattctta
    33241 accttatcag ttttttcata tatcttcatc tataccgacc atatattaat aaatgatatt
    33301 acatagactt aagtatatta aaaaacttaa atttagttat ttaacaacat aatactctaa
    33361 tttaatctat aaaaatccat acctaatata atgcaactct tattttaaca ccatctatta
    33421 cacaaaacaa catattaaaa agtaaaatac aaaatatcca ctataaacct tattttaata
    33481 ctgaatatat attataatat atttaatgta gcttaaatat agtttaaaca taaagaaagg
    33541 aaacggtata tgctaagaaa agataaagtt ctattatctc tacataaatt atgtgaaaat
    33601 atgactttaa aagaccttca atcagataaa acaggattca ctacaataga aattgctaac
    33661 cattcatctc ttgatagaag taataccagt aaagaattaa ataacctata caatgaaaaa
    33721 aaagttctga aaatatctgg taagccaatt ttatttctac atgctagtat tatagaaaat
    33781 ttaattggcc gtactttgaa cagtgatgaa ttttctataa ataattgtaa tgagctactt
    33841 aaatcaagta aaaatgactc agaagatatt ttttcaacat tacttggaca tgattctagt
    33901 cttaaactac ctatagaaaa agctaaatct gctatactct atcctccaaa aggtcttaat
    33961 acattactaa taggacctac tggtgttgga aaaagtacat ttgctgaaac aatgtacaaa
    34021 tatgctgtag aaagtaaaat cttttcttct gaaagcaaat tcgtagtatt taactgtgct
    34081 gaatatgcag aaaatgctaa cttattatta agtaatttat ttggttatgt caaaggttct
    34141 tttactggtg ctaataagga taaattcggc atagttgcac aggctgatgg aggcatatta
    34201 ttcttagatg aaatacacag attaccacca gaaggtcaag agatgctttt tcttttgatg
    34261 gacaaaggca tatacagacg attaggagaa tctgacattg tgcataaagc taatgtcttt
    34321 attgtgtgtg ccacaacaga agatatacat tcttctctgc ttggaacttt tttaagaaga
    34381 atccctgtta caatcaacct acctgcttta caggataggt ctttaaaaga aagattatct
    34441 cttattaaat acttctttat tatagaatca aaatacacca atgcaactat aaaagttcac
    34501 aaagatgtaa ttaaatcatt actcctttat gattgttttg gtaatatagg tcagcttaaa
    34561 tctgacatac aacttatgag tgcaagagcc ttcttaaatt acaaaactgg acttaaggat
    34621 aatatagaaa tagatttatc ccttgttcct gattacatct atattggtct tttaaaattg
    34681 aatgaaaatc gtagtaatct aaataaatta tcagaacttg attatatgct tttttatgaa
    34741 tttaatggta ataacttaga agttgaatat acaaaagaac tatctaaata caatatagat
    34801 acatcaaaca atggatttaa atactctaca gagattcctt atctggaaaa tgatataagg
    34861 agtatgttta taaattacat ggaaaagtac tctacaaaat tactttcgat atcttcagta
    34921 actcattctg attatacaag taatgagatt tttaaagtaa tcaatccaaa gatttactat
    34981 gctgttgaac attctttaaa agaggctgaa aaaatatcga gaaacaaata cacaaaacaa
    35041 acttatattg ctctttcaat gcatataagt gcacttatag aaaatataaa tcaagacaca
    35101 tataatccta agtacaattt atataatgat aaaattttct tagataaaga tttaaatata
    35161 gctaaaatag ttttaagtat aattgaaaat gacttacaaa catctttacc taaagatgaa
    35221 gtaaaattta tatccatgtt tctaaatagc atgtatcttg aaccaaacaa tcaatctgaa
    35281 agtataggag tcataatact tgctcatgga aattcaacag caagcagtat gtgtgatgta
    35341 gcaaattcat tgcttggtac aaaccattgt aatgcaattg acatgcctct tgatgtaaaa
    35401 gtaagtacca tacttgataa aactatagag ttggtaaaag aatgtgacga aggtaagggt
    35461 gtacttcttt taacagatat gggctctctt atagcttttg gagaacttat ttcagaaaaa
    35521 acaaaaatca aaactcgctc aattgaaatg gtatctactc caatagtttt agaagcagta
    35581 agaaaaagta cactaccaga aatgactttg gatgaattag ctaattcctt aagctcttta
    35641 aatccatata ttggacgagc agcaatcgat tcaacagaaa taaactatcc tgaaaagtca
    35701 agagagtatg taataataac tacttgtata acaggatatg gttcagctat gaaagtagca
    35761 gactttataa attcttcact taaaaatatt agtaaataca atattaattt agttcctcat
    35821 aatatagaaa gttttaaaat gtataagaat aaatttagta atactaaaat tctggcagtt
    35881 gttggaagtg tagattttaa tgtagccaac acccctttta tacacataga ggaactacta
    35941 aatggatatg gcctagatat gctaaacaaa ataatagaag gtacattcaa tgccaatagt
    36001 attacaaata taaaagaaac aaatctatca tacaacagtt taataataaa ctttatgacc
    36061 caaaacttag agcttttgga ctctgttaaa ttattcaact atgtcaattc ttccttattt
    36121 acaataatag aattaataga tgaaaactta aagagcaaat ttaagctagg atatatacta
    36181 cattgctctt ttatgataga aagatgtttt aaaaatacaa cttttccata taataacatt
    36241 actgaattaa ttagtaaaaa tcatgaacta tatagtttaa tacgtgaagc ctttaagcca
    36301 acagaagctt attttaatat tttgatacca gacgaagaaa ttgcttatat aatagacatg
    36361 attaatgagt atctaaataa ataaaattta tagcacttat tttgtgcata ttaattaata
    36421 tatgaaatgg aggacgagat tttgaaagga aaaataaaac agttaacaat acttgcatta
    36481 atttttatat ttataactcc tgtatttgca tttgcagata ctccaccagt accaaattct
    36541 tcaagagcag cactacttat agaccaggaa actaaaagaa tattatttga aaaaaacatt
    36601 gatgaaaaaa tgccattagc gagtttaagt aaaatgatga cctttttatt ggcaatagaa
    36661 gcagttgata aaaatcaagt taaagagact gatatggtga aaatagacaa gtctacagct
    36721 tcagtaggag gttctacttg taaacttaaa gatggtgatg aaatatctct aggagagctt
    36781 atgcagggtc taatgctagt atctggaaat gatgctgcta tagccatagc taaacatatt
    36841 ggtaaaactg aaaagaattt tgtaaatatg atgaacaaga aagcagaaga aataggaatg
    36901 attgatacgt attattttaa tccaaatggg cttcctatat atactgaccc agaacataaa
    36961 gaacctccta ttgaaaatat gtcaactgct cacgatatag ttacacttgg aaagtatatg
    37021 tacgaccatt atgaaaatca agttacaaga ataaccacta tgcaagtata taatgatact
    37081 aaaaaggatt ttacacatta taacacaaat cctctgcttg tttcagtacc tggtgttgat
    37141 ggaataaaga caggatatac agataatgct ggatattgcc ttgcattttc tatgatggta
    37201 cctaaagatg ctaaaaacga aagaaatcat agattgatag gtgttgtact tggtgatggt
    37261 aacaagaaaa atagaatttc ttcttccgct actttattga aatatggtaa agataatttc
    37321 cattctaaaa agatagcaca taagggtgat attatagaga ctccttgtgt tgatggtatt
    37381 gatgatttta agataacagt taaggttgat aaagatttgt atggtgttgt ttcagataac
    37441 gagaatatca atcctaaggt agtgtttaaa aatatgaatt atcctatcca taagggagat
    37501 attgttggtg ttgcaaagta ttataatgac tctggtaaat ttgttggaag tgttgatgta
    37561 aaaagtgaaa gtaatatagg atgtattcct ttgaaggata agattaagat taaggttgct
    37621 aagataaata aaaaacttga gattaaaaat tctgtttgtt ttaaagcata gtaaagcata
    37681 ttattaaaag ggtatgttaa atttataaag actccacttt gtggagtttt tttgtttttt
    37741 acaaaaaatt aaaatagtgg caacaattga ggatgtgagg gagagttgcc actattttgt
    37801 atagggtatt atattatgtt tttaagctag ttttactatc ttctatgttt atataataag
    37861 ccttgtatat gaatttaatt gataattaat atgaaaatta tgtgaagttt ttaattgatg
    37921 taaagtaata gattctattt agacacttaa aattataata aaacatctta atttttatat
    37981 ttatactaat taattctagt ataaatactt attaaatacc tttattcaaa cattatttca
    38041 gatttatact attcttatat gttaaaaggc tgtagaaaaa ttattttaaa aatcctacag
    38101 ccaatactag tatcatcaag aaaatttaca tcttattaaa ctaattttta ttcatatttc
    38161 attatttatt ttaatatatt aaataaactt gatagcccag aagatatttt tcctattgtt
    38221 gatattggat ctgacgcatg ttttttaact tcaaatgttg catttgctgc tgaatctgta
    38281 gcagttgttt cagatactgc tcctgcttta actaacacac ttatattatc taaatcagtt
    38341 tgtactgctt ggcttgctgt tcctgatact gttattgtta ttgtatttgc tgatgaatct
    38401 cc
//
LOCUS       DAEORM030000039        37954 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.039, whole genome shotgun sequence.
ACCESSION   DAEORM030000039 DAEORM030000000
VERSION     DAEORM030000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 37954)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37954)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 37954)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37954
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.039"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            198..1382
                     /locus_tag="KRH23_002456"
     CDS             198..1382
                     /locus_tag="KRH23_002456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YkvI family membrane protein"
                     /protein_id="HHS5225734.1"
                     /translation="MQKSVKKAKVTGSMLAIFGVASVLFSSHAGGGFATGNQETQYYV
                     QYGWTAPLMAILAMIILTATMREVIIMYNNNNCRNYKDLFCELWRPYPKLEIIWEIYY
                     YLMVLIAVSAVIAGAAAVFQSIGVNYFVAVFIIGVVLLVFTIFGAMLVSKAATAMTIA
                     ILVCTLTIFIVGIKAKVPEITEILSNRTSFTPGYIKPILNTFIYAGFQSVVIPTLAGC
                     SRPLLKNSKEATKAMIISFVMNAIALGLAVTMLMGWYREIIAAGQTTLPTLYVAGQSG
                     NHTIYIIYNVALFLCLMSTGVTTIFGLVNRFEDHKALSFLSSRMKRRVFTACAIMVVS
                     MLISLTGLSNIVKYGYGYCGYLGLFTIVIPFLTLGHYKNKKFAKENPEAKWPAELNEN
                     VN"
     gene            complement(1759..2886)
                     /locus_tag="KRH23_002457"
     CDS             complement(1759..2886)
                     /locus_tag="KRH23_002457"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HHS5225735.1"
                     /translation="MKGKITMDFKSLGISENTINILKKSGITTPTPIQKESIKLIKEG
                     KDVIAEAQTGTGKTLAFLLPIFENISLDINDIQVLILSPTRELAIQITEEAMKLKESK
                     DVSILAAYGGKDIGSQIKKLKGNIHMIIATPGRLLDHLNRKTIDLSKLKTFVLDEADQ
                     MLLMGFKNEVEAILKETSNKKQTLCFSATINSQVKKLAYRYTKNPVVVSIQKEEITLN
                     NIKQEVVETTDRKKLDALCKVLDEDNPFMAIIFCRTKRRVDNLEEALAIRGYNCQKLH
                     SDIAQSKRERIMKSFRNLDIQYLIATDVASRGLDISGVSHIYNYDLPETPEDYIHRIG
                     RTGRAGEEGYTCAFIDPKNERMLSEIETAIESKISRRIIEL"
     gene            3330..4523
                     /gene="nifV"
                     /locus_tag="KRH23_002458"
     CDS             3330..4523
                     /gene="nifV"
                     /locus_tag="KRH23_002458"
                     /EC_number="2.3.3.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004410 - homocitrate synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="homocitrate synthase"
                     /protein_id="HHS5225736.1"
                     /translation="MCVISKDRAKEIKIVDTTLRDGEQTAGVVFANREKIMIAEMLSD
                     LGVDQIEVGIPTMGGDEKNVIKHICSRNLKSDIMAWNRAVIKDVEESISCGVDAVAIS
                     ISVSDIHIENKLRTSRGWVLENMAKTVEFAKKNGLYVSVNGEDASRADIDFLTEFINV
                     GKQAGADRFRYCDTVGVMNPFSIKNAIETLYERTNFDIEMHTHNDFGMATANALAGIA
                     AGANYVGVTVNGLGERAGNAALEEVLMALKCVYKCDLNNIDTRKFRGICEYVAQASGR
                     ILPTWKPVVGDNMFIHESGIHADGALKDPHNYEPFDPSEVNLERKIVIGKHSGRAAVV
                     NKLSEYEMYISPENATKLLNAIRATSIRLKRSLMDKEILQLYCDILAHEKGTTEEEAV
                     RGSYI"
     gene            4548..6473
                     /locus_tag="KRH23_002459"
     CDS             4548..6473
                     /locus_tag="KRH23_002459"
                     /EC_number="4.2.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aconitate hydratase"
                     /protein_id="HHS5225737.1"
                     /translation="MGDNIVYKIIKKHIVDGEAVAGSSIGIKIDQTLTQDSTGTMTYL
                     QLEAMGIDKVKTKRSVAFVDHNMLQQGFENADDHKYIQTVADKYGVYFSKPGNGICHQ
                     VFLERFSTPGDTLLGSDSHTPTAGGVGMMAIGAGGLDVALAMAGGAYYIKAPKVCKVN
                     LVGKLNNMVSSKDIILEVLRKQTVKGGVGKVYEYGGEGVKSLSVPQRATITNMGAELG
                     ATTSIFPSDEKTLEFFKSQGREEAWIELKPNADAVYDEEITINLDELKPLAAKPHSPD
                     NVDEVENIGKIKIDQVAIGSCTNSSYEDLMKVAQILKGNKVHKDVSLVIAPGSRQVME
                     MIARNGALADIISAGARILENSCGPCIGMGQSPGTDSVSLRTFNRNFYGRSGTLSAQV
                     YLVSPEVAAVSAIKGVLTDPREFDIKFTNLDVNEFLIDDSMIIKPADVGSDVEVVRGP
                     NIKPFPLNTELSQSIGGKVILKTEDNITTDHIMPSNAKLLPFRSNIPYLANYCFNTVD
                     TEFPQRAKDNNGGFIVGGDNYGQGSSREHAALAPLYLGVKGVIVKSFARIHKANLINS
                     GIIPMEFCDEKDYENISLLDNLEIPNILDNLGSGILEVKNTTKGTSFKVKVELSAKEV
                     DVLKAGGKLNYTKNQAN"
     gene            6495..7490
                     /locus_tag="KRH23_002460"
     CDS             6495..7490
                     /locus_tag="KRH23_002460"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isocitrate/isopropylmalate dehydrogenase family
                     protein"
                     /protein_id="HHS5225738.1"
                     /translation="MYKVTLIPGDGIGPEVAKAMKKVVEATGVEIEWEEVNAGEAVIE
                     EYGTPLPEYIIDSIKKNKIAIKGPITTPVGKGFRSVNVTLRQALDLYVNLRPIKSFKG
                     IKSRYEDVDLVVVRENTEDLYAGIEHKIGDYAAESIKIITRSASERIVDFACNYVKDN
                     KRKKVTAIHKANIMKMSDGLFLDVFREVASKHGVEYDDLIVDAAAMNLVLNPENYDVM
                     VMPNLYGDILSDLGAGLVGGLGIIPSANIGKDCAIFEAVHGSAPQIAGQNKANPTALI
                     QSSVMMLRYLGEYENAQKIETALEKVFLEGSKLTVDLGGSASTTEFADEVCKYIV"
     gene            7840..8289
                     /locus_tag="KRH23_002461"
     CDS             7840..8289
                     /locus_tag="KRH23_002461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HHS5225739.1"
                     /translation="MIKTLDSNILREVGTLSRAVNSINDIKYKELKLQKGQFTFLTRI
                     CENPGINLVELSNMLKVDKATTTKAIQKLIKAGYVDKKQDKFDKRGYNLTPTDKSLEV
                     YELIIEEENRSIEICFDNFTDEEKQVVTKLLEKMSKNVENEWFKVKR"
     gene            8323..8817
                     /locus_tag="KRH23_002462"
     CDS             8323..8817
                     /locus_tag="KRH23_002462"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HHS5225740.1"
                     /translation="MIRKANMNDLESIMQIIKSTVEEMKTYNNTQWDENYPLEKDFVS
                     DIKKQDLYIYEVDGEVAGFICLNYEEPEEYLGLNWSSNKKAMVIHRMAVNPNFRKTGI
                     ASKLVDFAEKLAVENNVSYLKSDTYSINSKMNLLLTKCGFIKIGEMSFLGKEKSFYCY
                     DKIL"
     gene            8914..9435
                     /locus_tag="KRH23_002463"
     CDS             8914..9435
                     /locus_tag="KRH23_002463"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HHS5225741.1"
                     /translation="MIGFLKKRRSIRKYKDVEVEKEKLDKILKAALLAPSSKGLRTWE
                     FIVVDDKEKLINLSQCRTKGGGFFLKNAPLAIVIIADKEKNDVWIEDASIAASYIQLQ
                     AHELGLGSCWIQVRNRMHDDNIEADKYIREELKVPSKYSVECIISIGYPDEEKKAYGD
                     SDLDYKKVHFNNF"
     gene            9624..9935
                     /locus_tag="KRH23_002464"
     CDS             9624..9935
                     /locus_tag="KRH23_002464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHS5225742.1"
                     /translation="MGIFKTKMDEDWKVNYIKEFNEMRDSYESKLQKKQFEVDSLKSE
                     LDRLRSYKNSLKPKEKQITDDDINNIKSLRRDGLSYKEISNQTSWSKATVSRVLNGLY
                     D"
     gene            9963..10649
                     /locus_tag="KRH23_002465"
     CDS             9963..10649
                     /locus_tag="KRH23_002465"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0071586 - CAAX-box protein processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane glutamic
                     endopeptidase"
                     /protein_id="HHS5225743.1"
                     /translation="MKYSYKKCIIDSILLMFIVQILRMILNYVLLSQFEFTLENFNII
                     NLISFTLVGLSLILFLKDNSLYNKVRNRKITEAFEENKNNILIEKCKLILFVVVLSLA
                     IIVTYCTKGYVLFNVTMMTLSVLIVPIFEELFFREYIWNYLSNFIKSKSKIICITSIL
                     SGIYNIGYIDVIRNYVILYNNSSYTFEVIISKIMIGTVFGIVLGLVKYRFRDVGFCIL
                     LRSLFAIFIR"
     gene            10881..11765
                     /locus_tag="KRH23_002466"
     CDS             10881..11765
                     /locus_tag="KRH23_002466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fumarylacetoacetate hydrolase family protein"
                     /protein_id="HHS5225744.1"
                     /translation="MKFVTFCSSNEEKIGVFNSETNSIYEINSLGLSKLYTDMNDFIE
                     NVSTGDLEKIKNNSFENAKCYKLEEVKLCSPIVRPKKDIICLGLNYKDHVNEIPDGVI
                     KNVVMPDYPIYFSKRADKIIGVDDKISLHGDLVEKLDYESELAVIIGKEGINISKEDA
                     YEYIFGYTIVNDISERALQDKHVQWFRGKSLDTHTSMGPCIVHKEEFEHPLKLDISSV
                     VNGEVRQNSNTEYFIFDIPTIINDLSRGMTLKPGDIISTGTPAGVAMGMNPQVYLKHG
                     DIVECKVEGIGVLKNIVD"
     gene            11864..13039
                     /locus_tag="KRH23_002467"
     CDS             11864..13039
                     /locus_tag="KRH23_002467"
                     /EC_number="2.1.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003937 - IMP cyclohydrolase activity
                     [Evidence IEA];
                     GO_function: GO:0004643 -
                     phosphoribosylaminoimidazolecarboxamide formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolecarboxamide
                     formyltransferase"
                     /protein_id="HHS5225745.1"
                     /translation="MARELELKYGCNPNQKPSKIYMKNGELPIEVLNGKPGYINFLDA
                     FNSWQLVKELKEATGLPAATSFKHVSPAGAAVGVPLSDTLKQIYFVDDLELSPLACAY
                     AMARGADRMSSYGDFIALSDVCDKETATIIAREVSDGIIAPGYTDEALEILKGKRKGN
                     YNIVKIDENYTPEPIETKDVYGITFEQGRNEILINEDLLKDIPTDNKIFTDSAKRDLI
                     IALITLKYTQSNSVCYAKDGQVIGVGAGQQSRIHCTRLAGNKADTWYLRQHPKVLNLK
                     FKKDIGRPDRDNTIDVYLSDDYMDVLADGIWQNFFEEKPEPLTGEGKRAWLKTLTGVA
                     LGSDAFFPFGDNIERAKRSGVSFIAQPGGSIRDDNVILTCNKYNIVMAFTKNRLFHH"
     gene            13167..14021
                     /locus_tag="KRH23_002468"
     CDS             13167..14021
                     /locus_tag="KRH23_002468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5225746.1"
                     /translation="MALNIRNYSLLCNQGTAKFNEDVVGINPFGAWVLDGATGLNGKN
                     LVSTESDARWYVQWWNRYLYKNINKEESLKSIINTGIIEVKKEYELRLNGFKVEKLDL
                     PSSSIVVVKFHENKVEYFLLGDCALFIKNGDSKVIKDRSICKFDNTVFDEMSKLSNLE
                     EMAFDEIRTSVMDTIVSNRLKKNTKDGYWILDFDEEAVENSIYGYIEIKKDFQLMLTS
                     DGFTSACDRYNLIKEEELIRIAEKFGIGYIHNKVRDFEDNDYKAVKVPRFKVKDDSSC
                     LYLDIYND"
     gene            14065..15300
                     /locus_tag="KRH23_002469"
     CDS             14065..15300
                     /locus_tag="KRH23_002469"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006486 - protein glycosylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HHS5225747.1"
                     /translation="MKILHIITQKPNSTGSGIYLSGMIKGFEKIGHKQAVIAGIDVND
                     DVNCFPSEVSFYPVKYNCGELNFPVVGMSDSMPYESTRYKDLNIDMINRLKYQFKVNI
                     DKAMNDFKPELIICHHLYLLTAFVREMVKDIKVMSICHGTCLRQLNTIDLEKEYIIAN
                     IRKLDLIFALHENQKYDIIKTFGVSESKVVVIGSGYNDDIFYNKNYKIKDDKIKIVFA
                     GKICKSKGLIPFIKAISKLKYSKDLIEVNFAGTGSDIESYNEIVKLASKSPFKMNFLG
                     KLEQRDLAELFNRSQIFVLPSFYEGLPVVVLEALSCGTDVITTDILGVKEWIGSEINN
                     SGKIEYVSLPFMEKEGIPKDEELYDFENNLYNAIDSKIQSLLNNSNKKTSVDMSKKTW
                     DGLAYRINEVILMDELCLV"
     gene            15401..16342
                     /locus_tag="KRH23_002470"
     CDS             15401..16342
                     /locus_tag="KRH23_002470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp25"
                     /protein_id="HHS5225748.1"
                     /translation="MRISKKVLALGISALLLSVSFPTSINALDKIENIQGVDKYETAG
                     LISDKQDFTTAVLINADSTMVDGIAASGLAGVNNAAILLTNKDDIPEATLQRLNRVTK
                     IYVIGGENSISKDVEKMLLMRRMQVIRIDGVDRVDTSYKIAGEIEKIKNSDKMFLVNG
                     FKDEADAVSVASVAYRDGAPIILTKDIPSAEEDTDLDPWFGVSPVPVYAIGGESTLSD
                     YIVSRYRATRIGGVDRYQTNKNVIEKFYNGAKEFYITSGDDLVYALVASPLAKNAPVV
                     LVSNKSDKSILSGASKVTAIGISDKSIIEQCLDAVKK"
     gene            complement(16561..16914)
                     /locus_tag="KRH23_002471"
     CDS             complement(16561..16914)
                     /locus_tag="KRH23_002471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HHS5225749.1"
                     /translation="MDRKRELKQLYKEMKFDTGVFIIKNDITKKIYLGKSNDIKSKFN
                     SLKFQLGAGSCMIKELNNEWKKYGEKAFTFEVLELIKHDDNKTEKDYLEELDILEMVW
                     LEKLKEDNTYEIYSI"
     gene            17210..18121
                     /locus_tag="KRH23_002472"
     CDS             17210..18121
                     /locus_tag="KRH23_002472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CGNR zinc finger domain-containing protein"
                     /protein_id="HHS5225750.1"
                     /translation="MNKKIELIGNFASDWIRYSDYEYKITEEDELYIVPTEDAVFTMY
                     NPFDVADDIIVDIIRIGQEALQDISKETKEMKLKKEVLEFVKKYGLLGLIYSSVYNRD
                     IVGEERVLMIEKNYITKENILSTDEYVNMFIPFASDEDVYFKKYRRGIDVSKREESPK
                     FFGKRPLILDLVFSKFYTEQLDWIVSFAKDMCKHFNQICVYKNTSNLLTESVTIMSGG
                     FNPQKIGFSISQLDKPIIAWEFDSLKTAIETIYAFAITSEPSSLNKCKYCGKIYIPTN
                     SKSQYCSPSCRNCSNVKKSRSRAKKDK"
     gene            18381..18815
                     /locus_tag="KRH23_002473"
     CDS             18381..18815
                     /locus_tag="KRH23_002473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6323 family protein"
                     /protein_id="HHS5225751.1"
                     /translation="MISPIILSSINQNLKEIERNELLETNIESGDYGLALSESDVKDI
                     INSRDNTLKGYGRIELDIKVTKQLIENIYTSQYTNVDNYLEAINDMQEIFYYLKNETD
                     DKICDDEIIEILGEFYEKFSGNMDNVRGEADEFAKKFKFGEV"
     gene            18838..20373
                     /locus_tag="KRH23_002474"
     CDS             18838..20373
                     /locus_tag="KRH23_002474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6179 domain-containing protein"
                     /protein_id="HHS5225752.1"
                     /translation="MLNNLSNININENNLIKNQYSISLLKECLNCKVIDEREVYNIQQ
                     EVSLILMDLIKKYTNGQSTSVKTEVAEKLLISIWYAIDAYINKLGDIEKRVVELTAKN
                     VKKVYLGGIEILEEELVRLKDFYKLMMSRKLDTNSIAYNDTLMELSSFFKSYIVKFEA
                     QDVPVSIDYPLALDDMDVKGIYYVKNYIESIDIENRFCNLFKKKDREKLFYDYGVTYK
                     IDCDVILVNLFELIINNCIFSTILGNEVTNLEISKYEYEFLEKQFKNMYNNITEDKVI
                     GSEESNIIELIEVDDSFNTEVDSNLDYNDFEEINREIRINKKITLLLMEAIEVLIKRL
                     SIEDEDVIRYIKKYEKIFIESVLSSIKSNTFKSMVTVSKNKNEHLEDYIVDDESKLDD
                     ESFREIFNEILDSTSIIEKIRIIKENINAKKDFIDILESECLFGEEYLMLFASLSELE
                     LAILGSVVFYEDIRMREINILEFMLNEKTETTLWKIEYIKFMKRQSEDKIYSIEEHMN
                     KIN"
     gene            20457..21824
                     /locus_tag="KRH23_002475"
     CDS             20457..21824
                     /locus_tag="KRH23_002475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HHS5225753.1"
                     /translation="MKEYIINNVEEIREELIDLSKKIWENPELAFEEKYASSIQKEYL
                     KSKGFKIEEVENLPTGFIASFGDGKPVIGILGEYDALPELSQCVSAERKPLVEGKAGH
                     GCGHNLLGVAGVGAVVSIKKLIEENKFNGTIKYFGCPAEEEGGGKTVMCINGCFDDVD
                     CAFTWHPFDINAPWRGGSLANLSVKFKFKGITAHAAQAPHNGRSALDAVEIMNVGANY
                     LREHVIDSIRMHYVITNGGGRPNVVPGFAESWYFIRGKKAKDAEHVLDRLIKVAQGAA
                     MMTETEMEYKVTDGIYDYIPNQCLTDLVYDNMVFVGCPKNTPEEEEFAKKLCDTLTRE
                     ERLGVATSLQNDKSIVESYIHKEIVDGDKDKGLAGSTDVGDVSYVIPVAQFAMAAWPV
                     GIASHTWQSCSSAGSNIGFSAMINSAKVLACSAYDVFMDTKIIDEAKIEFDKSLDGQK
                     FKPLV"
     gene            21859..22083
                     /locus_tag="KRH23_002476"
     CDS             21859..22083
                     /locus_tag="KRH23_002476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015759013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NifU family protein"
                     /protein_id="HHS5225754.1"
                     /translation="MREKVEKVLEEKIKPVLQRDGGDVELIDVNENGVVLVRLQGACS
                     GCPGATMTIKAIIENVLVSEVPGVTQVLGV"
     gene            complement(22533..22931)
                     /locus_tag="KRH23_002477"
     CDS             complement(22533..22931)
                     /locus_tag="KRH23_002477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HsmA family protein"
                     /protein_id="HHS5225755.1"
                     /translation="MNYKLILAIVFITSALIFYTIGVFGERKAKILKKKHVIIFWLGF
                     IFDTLGTFTMSNIANSHTFEVKSALSQNLHSITGLLAIVLMLFHASWATFVLYKDDEE
                     KKKFFHKFSIVVWTIWLVPYFIGMFIGMAG"
     gene            complement(22934..23368)
                     /locus_tag="KRH23_002478"
     CDS             complement(22934..23368)
                     /locus_tag="KRH23_002478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HHS5225756.1"
                     /translation="MKSNYDCFRIAMLLKELYSKTMYTVEENFKENGLTHQQIIVIKL
                     IAHNQELTISQLCDEMSLAKGTVSGIISRLEQIGYIEKFKKSNDKRNTYVKFTTTGFE
                     FATNFKIKMQESFDDIFKNCDENELSDLVKNLRNILAKVKER"
     gene            23695..24681
                     /locus_tag="KRH23_002479"
     CDS             23695..24681
                     /locus_tag="KRH23_002479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHS5225757.1"
                     /translation="MLKDILKKLLQFILVMFLLSFIVFYMARLAPGDPLISYYGDGVE
                     RMSTQEKENAMKKLGLDEPIYSQYIKWISNASKGEFGISFKYKQNVTSVINDVYINTI
                     ILGGSGYILTFVLALLLGIFCTLHEDKLIDRIICKLGTITNCIPSFWVALVLILIFSI
                     NLSILPSSGAYSMGEESSILSRISHLILPLTVLILSHLWYYTYMIRNKLLEEIREDYV
                     LLCKAKGLNNRTIVFKHCLRNIMPSYISIMAISIPHILGGTYVVEKVFSYPGLGTLCF
                     ESAKYHDYNMLLVLCLITGALVVFGNMLAQIINNKIDPRMKYDRGDTNEATI"
     gene            24665..25576
                     /locus_tag="KRH23_002480"
     CDS             24665..25576
                     /locus_tag="KRH23_002480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHS5225758.1"
                     /translation="MKPQYSDFEIVGENYILVAEDEHIETKKTLSKKIKELPYISIII
                     LSIIVIGSVFSSFIMTHEPTYMDLASSNLAPNKTFLFGTDSMGRDIYSMIWYGGKISL
                     FIGLFSTVISTVIGIVYGSISGSASELVDDAMMRFTEIILSIPSILIIIFVQAILGNS
                     NPVSMSIVIGITSWMNISKIVRTEVRQIKNSEYILAAKSMGGGFFYVLKQHLLPNFVA
                     SIMFMVVTNIGAAIGTESTLSFLGIGLPIEIVSWGSMLSLSEEALLSNRWWIILIPGI
                     FLVTTLVCITNIGNYIRKNNNKKSSNL"
     gene            25689..27257
                     /locus_tag="KRH23_002481"
     CDS             25689..27257
                     /locus_tag="KRH23_002481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HHS5225759.1"
                     /translation="MKLKKLKVLSLVMILSLMAGCSSGGDKDKKADTPKDGKVLVYGS
                     NDYTSINPALYEHGEINSLIFNGLTAHDENNKVVPCLAKDWKFDEATNTYTFNLRDDV
                     KWHDGEKFTANDVKFTIETIMNPDNASEIASNYEDITKIDVVNDNTIKITLKAPNTAM
                     LDYLTVGVLPKHALEGKDIATDEFNQKPIGTGPFKLEKWDKGQSITLVKNSDYFVKEP
                     GLDKVVFKIVPDDKAKAMQLKSGELDLAQITPKDMSNFEKDEKNFKVNIMKTADYRGI
                     LYNFNSKFFKDKKAKGLPNALSYAIDRKAIVDSVLLGHGVPAYSPLQMGPYNNPDIEK
                     FEYNPEKAKQEIEKLGWKLGSDGIYEKEGTKLAFEITAGESDQVRVDMAKICAQQLKE
                     IGVDAKAVVVTETDWANQDAHLIGWGSPFDPDDHTYKVFGTDKGANYSAYSNPTIDKI
                     LQKARETEDKDEKLKLYKQFQVEMTKDMPYTFIAYIDAIYVGKPNIKGLTPDTVLGHH
                     GVGIFWNIADWTIE"
     gene            27332..28357
                     /locus_tag="KRH23_002482"
     CDS             27332..28357
                     /locus_tag="KRH23_002482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHS5225760.1"
                     /translation="MEHLLEVNNLSVSFKVEEGEVQAVRNVSFNLKKGETLAIVGESG
                     CGKSVLCKSLMRILPYNGYIKNGEVLLKSSDLVKKSEKEMEDIRGKNISMIFQDPMTS
                     LNPTISIGKQIAEAVIIHQGISKSEAKKRAIELIELVGIDNPEKRFKQFPHHFSGGMR
                     QRIVIAIALACNPDVLIADEPTTALDVTIQAQIIDLIKDLQHKIGLSIIFITHDLGVV
                     ATIADRIAVMYAGKIVEIGTVEDIFYDPRHPYTWGLLGSLPTLDSQDDYLYNIPGMPP
                     NLLNPPKGDAFAIRNKNALKIDYEKEPPMFKINDTHSAATWLLHPDAPEVDVPVRVNC
                     GRVISNE"
     gene            28350..29294
                     /locus_tag="KRH23_002483"
     CDS             28350..29294
                     /locus_tag="KRH23_002483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHS5225761.1"
                     /translation="MNREKILEIKNLKQYFHLDKSTTVKAVDDISFDIYKGEIFGLVG
                     ESGSGKSTTGKTIIRLHESTGGEVIYKGNCISDKKTYKFIKKDVNKSMQIIFQDSTSS
                     LNPRMTIADIISEPLKIQGICKNKTDRMNKVYEMLKLVGLDRSYANKYPSDFSGGQRQ
                     RIGIARALSVDPEFIIADEPIASLDVSIQAQIVNLFKKLQQEKNLTCLFIAHDLSMVR
                     HISDRIGVMYNGKLVELADSNELYNNPIHPYTKSLLSAIPVPDPRYAKSRNRIEYNSN
                     GYDCSNEKLLSWIEVSDGHFVYSSKSDISKYQQNLKVV"
     gene            29653..32310
                     /locus_tag="KRH23_002484"
     CDS             29653..32310
                     /locus_tag="KRH23_002484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HHS5225762.1"
                     /translation="MIYKKDKVMKVLESSYRENEKGITANQLSEKTGIARNNISTYLN
                     QLFNEGMVTKIKGRPVYYIPANLNLNKNELLDTQSELLGIKKGTKVENKIKKDSFETL
                     IGKEHSLRPIIEKCKVAMLYPTNGLHTIIYGETGVGKSMIARYMYDYSIDSGIRKNKA
                     PFVTFNCADYANNAQLLMGHIFGVEQGAYTGAESSRKGLLEIANGGILFLDEIHRLPA
                     EGQEMLFTFIDKGTFKRLGDATKERESKVLIICATTENPTSTLLDTFNRRIPMKIEIP
                     SLRDRTMIERMELVKNFFKEESKSISISIKVHKEIIKSLLLYDCKNNVGQLQNDIKLA
                     VANGYLRYKRDNKEPVYIEKKYFDKSINEVSDDYREKSIKADEVITHGIEYFVFTSLG
                     EEEVINYNDINIINAVNTNLNKSVEMNIADASLFNNVKFKSMCESIRQIIKEDEEIDI
                     SESIFKSMAIYIKSVLDKSSSTNNIDLNQIRRNNRSEFKTALKIVGIIENEFDLFLSI
                     ETVAYITLFIVQAKQDEQNKIVNNINIIVAMHGETTASSMVKAVGDIIVKCSAISFDM
                     KLDKSYDEVIVDFKNLINNIDNKDVLLFTDMGSLNSFDEIIKKEKKCGVRVIPMVTTL
                     TVLEAVQKANMGLPLNDVYNSITNTRKYYFGTNEIQNKENLSKTIIIASHVSEGVDNK
                     TRKILEEKMSRYLDGIDIISVPYKTEKDLSLNITKLKESSNIVAVINEQRINIRGIDY
                     ISKKDIDKDENINKLKNIIKISIGYDDVVEGLKTSLKSSNYNRIFKDIKYVSDELFLV
                     FNIEKKYDKVIGLMMHLAFMVDGLIGNTREIEKLDKEKTLDYHKSLSKIKDIVSQLDK
                     KYNIEINEKECYQILLILEYAEIIEKDYQ"
     gene            32525..33154
                     /locus_tag="KRH23_002485"
     CDS             32525..33154
                     /locus_tag="KRH23_002485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5225763.1"
                     /translation="MQDKILRDKKANDPWARMTTRNGFSADEIISSFQKAIRRNMVEE
                     ACEFAYELYISSPELEDKLWRRILTISVEDIGMGDPSAVIIINNLNQVRKEYSYADGD
                     RPLFFIHAIRYLCACEKDRSSDLLKNIIIKGFAMGKVPEVMDVALDKHTYRGLEMGRD
                     SFHFLNEASIVIPEKEVDNDYKERYLKILEKYKQEEVIDTAFKFNHWQY"
     gene            33289..33615
                     /locus_tag="KRH23_002486"
     CDS             33289..33615
                     /locus_tag="KRH23_002486"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HHS5225764.1"
                     /translation="MNILLVCANGASTGVLVEKMKSFCSEHEKLKTKTINIEATSFEN
                     LKSYIEANDTDVVLVAPQIRFKEDDVVEACKNYKIAVGLIDTKHYGRMDAPSVMKSAI
                     ELYKNR"
     gene            33631..34920
                     /locus_tag="KRH23_002487"
     CDS             33631..34920
                     /locus_tag="KRH23_002487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HHS5225765.1"
                     /translation="MEALQNNLRRFLLPIAQKIEKQRHLQAIKEGMISITPIIIVGSL
                     SMLFMALNNMLPEGSAKTLLSENMDTLLIPNKFTMSLLSIYSAFFIAQALAKKYNLNH
                     VEIGMTAVVAQLVVCGQVVDGVLDTSYLDAQGLFVSILVALLVVDITKFMNDKNLVIR
                     FPKEVPSVVNKSFRNLTPMIVCIMLFTAIAAITKNVSGQPLPAIIMNFLAPAISSVDN
                     VFAVTIILFITQLLWFFGLHGAAITSSIWMPIAATYMAENATLIAAGGDPKYVFTIGF
                     YYGFLQVTGSGITLGLVYLMSRSKCKSFNSMGKVVILPSLFGINEPVIFGTPIVMNPY
                     MFVPFVFGPVLVGALNFMALKVGLVGLPIAEPPGFLPPGVAAFLMTLDWKAIVLVFAS
                     IILMTLIYYPFFKIMEKEELNKNAELATTLDDDSFDF"
     gene            34944..35273
                     /locus_tag="KRH23_002488"
     CDS             34944..35273
                     /locus_tag="KRH23_002488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HHS5225766.1"
                     /translation="MVPEMEEKVFSIISEAGDAKSDVMMSLKEIKKGDYNKAKHLLNS
                     ASEKIQTASKHHLELLSNAMNSEDSGTDFLVVHSEDHYSNALFAHSLVSELVDIFEMM
                     DPRINKN"
     gene            35421..36749
                     /locus_tag="KRH23_002489"
     CDS             35421..36749
                     /locus_tag="KRH23_002489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-alpha-glucosidase"
                     /protein_id="HHS5225767.1"
                     /translation="MEKFSVVIAGGGSTYTPEIILMLLDNLDRLPLRAIKLYDNDEER
                     QNKVAKACEILIKEKDPNIEYLATTCPKEAYTDVDFCLAHIRVGKLEMRELDEKIPLK
                     HGVVGQETCGPGGIAYGMRSIEGVLENIDYMEKYSPNCWMLNYSNPASIIAEAVRRLR
                     PNSRVINICDMPIGMEHNIARIAGLKSRKHMDIRYFGLNHFGWYTSIKDKKGNELLPK
                     LVEHIKEYGFINGEEGMKNDKKDSWFETNLFTKEIVKTDLTTIPSSYLKYYLFPDYVV
                     NHSDVNYTRANEVIDGREKEVFGSCALIEKQGHSKGSGLKIGIHAEFIVDLATALAFN
                     TQERMLLIVQNNGAIENIQDDAMVEIPCIVGKDGYEPLSIGKIPTFQKGLIEQQLAVE
                     KLVVDAWIEKSYNKLWQALMLSKTVPSATVAKELLDDLIEANKNYWPKLN"
     gene            37072..37926
                     /locus_tag="KRH23_002490"
     CDS             37072..37926
                     /locus_tag="KRH23_002490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-ADP-ribose hydrolase"
                     /protein_id="HHS5225768.1"
                     /translation="MKWRDYADDVNLFEDFDKTIKPLTDEQRRKNINTLIAYFSKEVP
                     SKIYNLSNDEIKPRDILRGLLNVYPPKEIAPEILNMLHNLLLIECEERELVDVNDIEE
                     VEEGIAIWRGNITNLRADAIVNAANNKLLGCLQPLHLCVDNEIHSCAGPRLREDCDKI
                     IKKQGHLEYTGDAKITRGYCLPAKFVVHTVGPIVSGGQPSKEQEKQLLHCYKSCLNTI
                     KEIDEIKNIVFCGISTGVFGYPKKEAANLAVSRVRLWLKENPEKNLKVVFNVFTEEEE
                     EKYRRIFK"
BASE COUNT        14990 a         3962 c         6798 g        12204 t
ORIGIN      
        1 aaaaacaaag tgaatttgaa tactatttaa aaaataaaat aaatatataa aaaatattta
       61 atataaaggt agaaataagt tgaaaatgta aagtcattgg aaaaatatag ttgaatttaa
      121 tgagcaaaaa tgttattgtt ttatcaataa agtgttaaaa taaaaacttt caatatcatt
      181 ttagggagga tgatttcatg caaaaaagtg taaagaaagc aaaagtaacg ggctctatgt
      241 tagccatttt tggtgttgca agcgttcttt ttagttcaca tgcaggagga ggatttgcta
      301 cagggaatca agaaactcag tactatgtgc agtatggatg gacagcaccg cttatggcaa
      361 ttttagcaat gattatactt actgctacca tgagagaagt tatcataatg tataataata
      421 acaattgtag gaattataag gatttatttt gtgagctttg gagaccatat ccaaaacttg
      481 aaataatatg ggagatatat tactatctaa tggttttaat agctgtaagt gctgttatag
      541 caggtgcagc agcagtattt caaagtatag gagtaaatta ttttgtagct gtatttatta
      601 ttggagttgt acttcttgtc tttactatat ttggtgctat gcttgtatct aaagcagcta
      661 cagcaatgac aatagctatt ctagtatgta ctcttactat ttttattgtt ggtataaaag
      721 ctaaagtacc agaaataact gaaatattat caaatagaac gagtttcaca cctggctata
      781 tcaagccaat acttaatact tttatttatg caggttttca atcggttgtt atacctacac
      841 ttgcaggatg ttcaagacca cttcttaaga actcaaaaga agctactaag gcaatgataa
      901 tttcatttgt tatgaatgca attgcattag gacttgctgt aactatgcta atgggatggt
      961 atagagaaat tattgctgct gggcaaacaa cactccctac tctttatgtt gcaggtcaat
     1021 ctggaaatca tactatatac ataatttata atgttgcatt attcctttgt ttaatgtcta
     1081 caggagtaac tactatattt ggtcttgtaa atagatttga agaccataaa gcactttctt
     1141 tcctttcttc aagaatgaaa agaagggtat ttacagcttg tgcaataatg gtagtgtcaa
     1201 tgcttatatc acttacagga ttaagtaata ttgttaaata tggatatgga tattgtggtt
     1261 atcttggtct attcactata gtaattccat tccttacact aggacattat aagaataaga
     1321 agtttgcaaa ggaaaatcca gaagctaaat ggccagcgga attaaatgaa aatgtaaatt
     1381 agatgtagta gcaaaaaata ttgctaaaga gaatactata gataagaata ctatagataa
     1441 tatatctgca tgtttattaa gattatttgc aaaatctaat attaaacaac tataaacaag
     1501 caatataaaa ctaagaataa aagataaaaa gagggtgtct caaaatggac ttttagttta
     1561 taaggcactc ttttttatat gaagtcaaat atattttcat tattttgaca ataaaagaga
     1621 ctaatcctac tttggatagc ctcttttttc tttaatataa aatagtataa cagcaaagta
     1681 tagattgata catgttttct gtagctttct atatattaca gtgtttgtgt ggcattggta
     1741 ttttaagcaa tctataaatt ataattctat aattcttcta ctaattttag attctatagc
     1801 cgtctctatt tcacttaaca ttcgttcatt tttagggtca ataaaagcac atgtatagcc
     1861 ttcttcacca gctctaccag ttctaccaat acggtggatg tagtcttctg gtgtttctgg
     1921 taaatcgtaa ttatatatat gacttactcc agatatatca agaccacgag aagctacatc
     1981 tgtagctatt aagtattgta tatctaaatt tctaaatgat ttcattattc tttctcgttt
     2041 tgattgagca atatcactat gaagtttttg acaattatat cctcttatag caagagcttc
     2101 ttcaagattg tcaacccttc tcttagttct acaaaatatt attgccataa aaggattatc
     2161 ttcatctagt accttacata aggcatctaa tttttttcta tctgtagttt ctactacttc
     2221 ttgttttata ttattaagag tgatttcttc tttttgaata gaaactacaa caggattttt
     2281 tgtgtatcta taagctaatt tttttacttg agaatttata gttgcagaaa aacatagtgt
     2341 ttgctttttg tttgaagtct cttttaaaat agcttccact tcatttttaa atcccataag
     2401 caacatttgg tctgcttcat ctaaaacaaa agtctttaac ttactaaggt ctattgtttt
     2461 tctatttaga tggtctaaaa gcctacctgg tgtagctata atcatatgaa tatttccttt
     2521 tagtttcttt atttgagaac caatatcttt tcctccatat gctgcaagaa tacttacatc
     2581 tttagattct ttaagtttca tagcttcttc tgttatttga atagctagtt ctcttgtagg
     2641 agaaagtata agtacttgta tatcatttat atctaatgat atattttcaa atatcggaag
     2701 taaaaaagct agtgtttttc ctgttccagt ttgagcttct gctattacat cttttccttc
     2761 ttttattagt ttaatacttt ctttttgtat aggtgtaggt gttgttattc ctgatttttt
     2821 tagaatattt attgtatttt cactaatccc taagcttttg aaatccattg ttatcttacc
     2881 tttcatgaaa aattttcttt tttattaacc aattaataat atcatattta taagtatttt
     2941 tagtaaattt tttaattatt atttatatag cttaaaaata tattaagata ctttaaaatg
     3001 gaatgtaact taaattaaat tttagtagga attttatagg tttattttta aaggtttttt
     3061 gaaaataaat ctatttaaaa attaaattaa aatgcaagaa aaacataata actttcattt
     3121 ttaagaagtt ttcacaaaaa agaaaaaata tagtgcaata aatgatacaa agtaatataa
     3181 tagattacaa gatatgaaaa gctaaaaaaa taaattgcaa atgaaattaa aatgaataaa
     3241 aaataaaaaa ataatcataa gttagaggta tcaatgaaaa ataagactta atgttttaaa
     3301 attaaaagta tactaagggg ggcattaata tgtgcgttat atcaaaagat agagcaaagg
     3361 aaataaaaat agtagatact actttaagag atggagagca aacagctggg gttgtatttg
     3421 caaatagaga aaaaataatg attgctgaaa tgttaagtga cctaggtgtt gaccaaattg
     3481 aagttggtat acctactatg ggtggagatg aaaaaaatgt aataaagcac atatgtagta
     3541 gaaatttaaa atcagatata atggcttgga atagagcagt aataaaagat gttgaagaat
     3601 ctatttcttg tggtgttgat gcagtagcta tatcaatatc agtatctgac attcatatag
     3661 aaaataaatt gagaacttct agaggctggg ttttagaaaa tatggctaaa acagttgaat
     3721 ttgcaaagaa aaatggatta tatgtttcag taaatggaga agatgcttca agagcagata
     3781 tagacttctt aactgaattt ataaatgttg gaaaacaagc aggggcagat agatttagat
     3841 actgtgatac agtaggagtt atgaatcctt tttctataaa gaatgcaata gaaactcttt
     3901 atgaaagaac taattttgat atagaaatgc atacacataa tgactttggg atggcaactg
     3961 caaatgcact tgcaggaata gcagcaggag caaattatgt tggtgttaca gtaaatggat
     4021 taggtgaaag agcaggaaat gcagcattag aagaagtttt aatggcactt aagtgtgttt
     4081 ataaatgtga tttaaataat atagatacta gaaaatttag aggaatatgt gagtatgtag
     4141 cacaggcatc aggaagaata cttcctacat ggaaaccagt agttggggat aatatgttta
     4201 tacatgaatc tggtatacat gcagatggag ctttaaaaga cccacataac tatgaaccat
     4261 ttgacccaag tgaagtaaat cttgaaagaa aaatagtaat aggtaaacat tcaggaagag
     4321 ctgcagttgt aaataagttg agtgaatatg aaatgtatat ttctccagaa aacgctacca
     4381 agctattaaa tgctataaga gctacatcta taagattaaa aagaagttta atggataaag
     4441 aaattcttca attatattgt gatatactag cacatgagaa aggcacaaca gaagaagaag
     4501 cagttagagg ttcatatatt taagatataa ttgtttagga ggaaaatatg ggagataata
     4561 tagtttataa aataattaaa aaacatatag tagatggaga agctgttgct ggaagttcaa
     4621 ttggtataaa aatagaccaa actttaacac aagattctac tggaacaatg acatatcttc
     4681 aactagaagc tatgggaata gataaagtaa agactaaaag aagtgtggca tttgtagacc
     4741 ataatatgtt acaacaagga tttgaaaatg cagacgacca taagtatata caaacagtgg
     4801 cagataaata tggagtttat ttctctaagc caggaaatgg tatttgtcat caagtatttt
     4861 tagaaagatt ttcaacacca ggagatacac ttttaggttc tgatagccac acacctactg
     4921 ctggaggtgt gggcatgatg gctattggag ctggtggatt agatgttgct ttagccatgg
     4981 caggaggagc atactatata aaagcaccaa aagtctgtaa ggtgaatcta gttggaaaat
     5041 taaataatat ggtatcatca aaagatataa tattagaagt gttaagaaaa caaactgtaa
     5101 aaggtggagt aggtaaagtt tatgaatatg gtggagaagg tgtcaaaagc ctatctgttc
     5161 cacaaagagc tacaataaca aatatggggg ctgaacttgg agcaactact tcaatcttcc
     5221 caagtgatga aaaaacacta gaatttttta agagtcaagg aagagaagag gcatggatag
     5281 agctaaaacc aaatgcagat gcagtttatg atgaagagat tactataaac ttggatgaat
     5341 taaaaccatt agctgcaaaa cctcatagcc cagacaatgt agatgaagtt gaaaatatag
     5401 gcaagattaa aatagaccaa gtggcaatag gaagttgtac aaattcttct tatgaagact
     5461 taatgaaagt agcacaaatc ctgaaaggaa ataaagtaca taaggatgtg agtttggtaa
     5521 tagcaccagg ttcaagacaa gttatggaga tgattgctag aaatggggct ttggcagata
     5581 taataagtgc tggagctaga atactagaaa attcttgtgg tccatgtatt ggtatgggtc
     5641 aatctccagg tactgactct gtgtctttaa gaactttcaa tagaaatttc tatggtagaa
     5701 gtgggacttt gtcagcacaa gtatatttag taagtccaga agtggcagca gtaagtgcaa
     5761 tcaagggagt gcttacagac ccaagagaat ttgatattaa atttacaaat ttagatgtaa
     5821 atgaattttt gatagatgat agcatgataa ttaaacctgc tgatgtagga agtgatgtag
     5881 aagtagttag aggacctaat ataaaacctt tccctcttaa tacagagcta agtcagtcta
     5941 taggtggaaa agttatatta aagacagaag ataatataac tactgaccat ataatgccat
     6001 caaatgctaa gttacttcct tttagaagta atataccgta tcttgcaaac tattgtttca
     6061 atactgtaga tacagaattt cctcagagag caaaagacaa taatggtgga tttatagttg
     6121 gtggagataa ttatggtcaa ggttcaagta gagaacatgc agctttagca ccattatatc
     6181 taggtgttaa aggggtaata gttaagagct ttgcaagaat ccacaaggct aacttgataa
     6241 atagtggtat aattccaatg gagttttgtg atgagaaaga ttatgaaaat atatctcttt
     6301 tagataatct ggagatacca aatattttag acaatctagg tagtggaatt ttagaagtta
     6361 agaatacaac taaaggaact tcttttaagg tcaaagtaga attgtcagca aaagaagttg
     6421 atgtattaaa agctggtgga aaattaaact acactaaaaa tcaagctaat taatatgaaa
     6481 agagggaata ttgaatgtat aaagtgacac ttataccagg agatggaata ggaccagaag
     6541 ttgcgaaagc tatgaaaaag gtagtagaag ctactggagt agaaatagaa tgggaagaag
     6601 ttaatgcagg agaggcagtt attgaagagt atggtactcc acttcctgaa tatattatag
     6661 atagtataaa aaagaacaaa atagctataa aaggcccaat tactactcct gtaggtaaag
     6721 gatttaggag tgtaaatgta actttaagac aggcattaga tttgtatgtc aatttaagac
     6781 ctattaaaag ttttaagggg ataaaatcaa gatatgaaga tgttgattta gtggttgtaa
     6841 gagaaaatac agaagattta tatgctggaa tagaacataa aataggtgat tatgcagctg
     6901 aaagtataaa gataataaca agaagtgcaa gtgaaagaat cgttgatttt gcatgtaact
     6961 atgttaaaga taataagaga aaaaaagtta cagctataca taaggcaaat ataatgaaaa
     7021 tgtctgatgg attgttttta gatgtgttta gagaagttgc atcaaaacat ggtgtagaat
     7081 atgatgattt gattgtagat gcagcagcta tgaacttagt tttaaatcca gaaaattatg
     7141 atgtaatggt aatgccaaat ctttatggag atatactatc agatttaggt gctgggcttg
     7201 ttggaggttt aggtataatt ccaagtgcaa atattggtaa agattgtgcg atatttgaag
     7261 ctgttcatgg aagtgctcca caaatagcag gtcaaaataa ggctaatcca acagcactta
     7321 ttcaatcatc agtaatgatg cttagatact taggtgaata tgaaaatgca caaaaaatag
     7381 aaacagcttt agaaaaagta tttcttgaag gaagtaaatt gactgtagat ttgggtggct
     7441 cagcttctac tacagagttt gcggatgagg tgtgtaagta tattgtatag attttattta
     7501 gggaaaaagt aaaatataga ttgaaggaaa gaggctttct caaaatagag ataagccttt
     7561 tttattggaa tgataaaata tatttgattt tatacaaaag agagttcctc ataaacgaaa
     7621 aagttaattt tgggatatcc attttaattt taaaattaat tgattaatat gcaaagaaag
     7681 attaaataaa tttattattt ttaattgaac tttcaaccaa aatatggtaa aatttaaaaa
     7741 agttgaactt tcaactaaaa atgaatatat tgattatgtg aaattttata aaacagaaac
     7801 tatttgactt tagccatagt agtttcagtg gaggtgtgtt tgattaagac tttagatagt
     7861 aatatattaa gagaagtagg tactttatct agagcagtaa attcaataaa tgatattaag
     7921 tacaaggaat taaagttaca aaaaggacaa tttacatttt tgacaagaat ctgtgaaaat
     7981 cctggtataa atcttgtgga attatcaaat atgttaaagg tagacaaggc tacaacaacc
     8041 aaggctatac aaaaattaat aaaggcagga tatgtagata aaaagcagga taagtttgat
     8101 aaaagaggat ataatttaac tccaactgat aaatctttgg aagtttatga gttgataatt
     8161 gaagaagaga atagaagtat agagatatgt tttgataatt ttacagatga agaaaaacaa
     8221 gtggtaacta agttattaga aaaaatgagc aaaaacgtag aaaatgaatg gtttaaagta
     8281 aagagatagt aaataaatac attaacttaa ggagatattt ttatgattag aaaagcgaat
     8341 atgaatgatt tagaaagcat tatgcaaatt ataaaatcta cagtggaaga aatgaagact
     8401 tataataata cacaatggga tgaaaactat ccattagaaa aagactttgt ttcagatatt
     8461 aagaaacaag atttatatat ttatgaagtg gatggagaag tagcagggtt tatatgtctt
     8521 aattatgaag agccagaaga atatttaggc ttaaattggt catctaataa aaaagcaatg
     8581 gtaatacata gaatggctgt aaatccaaac tttagaaaga caggaatagc atctaagtta
     8641 gttgattttg ctgaaaaatt agctgtagaa aacaatgtat catacttaaa gagcgataca
     8701 tattcaataa actcaaaaat gaatttatta cttacaaagt gtggttttat aaaaatcgga
     8761 gaaatgagtt ttttaggaaa ggagaaatct ttctactgtt atgataaaat attataaaga
     8821 gcatttataa tacaagggat aaataataga ttttcagcat tagtaagggc ataatataac
     8881 ctagtgtatg ctattatgaa agggatgatt tatatgattg gatttctaaa gaaaagaaga
     8941 agtattagaa aatacaagga tgttgaagta gaaaaagaaa aattagataa aatattaaaa
     9001 gctgctcttt tagctccatc atcaaagggg cttagaacat gggaatttat agtggtagat
     9061 gataaagaaa agctaattaa tttatctcaa tgtagaacta aaggtggtgg atttttctta
     9121 aaaaatgcac ctttagctat tgtaattatt gcagataaag aaaaaaatga tgtttggata
     9181 gaggatgcaa gtatagctgc ttcatacata caacttcaag ctcatgaact aggtttaggt
     9241 tcttgttgga tacaagtaag aaatagaatg catgatgata atatagaagc tgataagtac
     9301 attagagaag aattaaaagt acctagcaag tacagtgtag aatgtataat ttctatagga
     9361 tatcctgatg aagaaaagaa agcatacggt gactctgatt tagactataa aaaggttcat
     9421 tttaacaact tttagtatat aatatgttgt attaagacat tatatttttt tctattgtta
     9481 atatatactt aaaattgtaa aaatatatct gaattttact aacttatcta ggggttatgt
     9541 acaaggattt taaagataaa tatagaaatt aatgtttata atcgatacat aacttgagta
     9601 acaaaattta aggaggttaa agtatgggta tatttaaaac aaaaatggat gaggactgga
     9661 aagtaaacta cattaaagag tttaatgaaa tgagagattc ttatgagagt aaacttcaaa
     9721 aaaaacagtt tgaggtagat agtttgaaat cagaattgga tagactaaga agctataaaa
     9781 atagccttaa gccaaaagaa aaacaaatta ctgatgatga tataaataat ataaagagtt
     9841 taagaagaga tggcttaagc tataaagaaa tttcaaatca aacaagttgg agcaaagcaa
     9901 ctgtaagtag ggtattaaat ggactttacg attagcatat acatggggtg atttaaattg
     9961 ggatgaagta tagttacaaa aaatgcataa tagattctat tttattgatg tttatagttc
    10021 aaatattaag gatgattttg aattatgtac ttctaagtca atttgaattt actcttgaaa
    10081 attttaatat tataaactta atttctttta cattagttgg tttatcgtta attttatttt
    10141 taaaagataa ttctttgtat aacaaggtta gaaatagaaa aatcacagaa gcttttgaag
    10201 aaaataaaaa caatatactt attgaaaagt gtaagctgat actttttgtt gtggttttat
    10261 ctttagcaat aattgtaact tattgtacta agggatatgt actttttaat gtaactatga
    10321 tgactttgtc tgtattgata gtcccaatat ttgaagagtt attttttaga gaatatatat
    10381 ggaactatct aagtaatttt ataaagtcaa agagtaaaat tatctgtata acatctatac
    10441 tatctggaat ttataatata ggatacatag atgttataag aaattatgta atattgtata
    10501 acaattcaag ctacaccttt gaagttatta tttcaaaaat tatgataggt actgtttttg
    10561 gtattgtact tggattagtt aagtataggt ttagagatgt agggttttgt atattattga
    10621 ggagcttatt tgctatattt attaggtaga tagtataatc ggtttataag gttgttttaa
    10681 atttaatttt aaatcaacct tattttattt gtgttttata aagcacttat atattaataa
    10741 ctaataaatt taataaaaat tatttgaata tttttaaaat atataaatat gtattgacat
    10801 ataaatatta tgaattacaa tttatataaa ctaataaaaa ttaaataata ttaatcaact
    10861 tattgaatgg aggaataaaa atgaaatttg tgactttttg tagtagcaat gaagaaaaaa
    10921 taggtgtatt taattcagaa acaaatagta tatatgaaat taatagttta ggattaagta
    10981 aattatatac tgatatgaat gattttattg aaaacgtatc tacaggagat ttagaaaaaa
    11041 taaaaaacaa ttcatttgaa aacgcaaagt gttataagtt agaagaagtt aaattatgtt
    11101 ccccaattgt aagacctaaa aaagatatta tatgtttagg tctaaactat aaagaccatg
    11161 tcaatgaaat cccagatgga gttataaaaa acgtagttat gccagattat ccaatttatt
    11221 tttctaagag agcagacaaa ataattggag tggatgataa gataagctta catggagatt
    11281 tggtagagaa gttggactat gaatcagaac ttgcagtaat cataggtaaa gaaggtataa
    11341 atatatcaaa agaagatgct tatgaatata tatttggata tacaatagta aatgatataa
    11401 gtgaaagagc acttcaagat aaacatgttc aatggtttag aggaaaaagc ttagacacac
    11461 atacatctat gggaccttgt atagtacata aagaagaatt tgaacatcct ttaaaattag
    11521 atataagtag tgtagtaaat ggagaagtaa gacaaaattc taatacagag tactttatat
    11581 ttgatatacc tactataata aatgatttat caagaggaat gactctaaag ccaggagata
    11641 taatttcaac tggaactcca gcaggggttg ctatggggat gaatcctcaa gtatatttaa
    11701 agcatggcga tatagttgaa tgtaaagtcg aaggaatagg agttttaaaa aatatagttg
    11761 attaatggat aaatatgcca tataatttta ttagtacgaa taatttaatt aatataggat
    11821 taatcaaact tatgattaat ttattataga gagggatgag tatatggcaa gagaactaga
    11881 attaaagtat ggctgtaatc caaatcaaaa accatcaaag atttatatga agaatggaga
    11941 acttcctata gaagtattaa atggaaaacc tggatatata aattttttag atgcatttaa
    12001 tagttggcaa cttgtgaagg aattaaaaga agctacaggt cttccagcag caacttcatt
    12061 taaacatgta agtccagcag gagcagcagt aggggtacct ttatcagata ctttaaagca
    12121 aatatatttt gttgatgatt tagagctttc tccattagct tgtgcttatg caatggcaag
    12181 aggagcagat agaatgtctt cttatggcga ttttatagca ctttcagatg tatgtgataa
    12241 ggagactgca actattatag caagagaggt ttctgatggt ataatagctc caggatatac
    12301 agatgaagcc cttgaaatat taaaaggaaa gcgtaaaggt aactataata ttgtaaaaat
    12361 agatgaaaat tatactcctg aacctattga aacaaaggat gtttatggaa ttacttttga
    12421 acaaggtaga aatgaaatat taataaatga agacctatta aaagatattc caactgataa
    12481 taaaattttt acagatagtg caaaacgtga tttaattata gctcttatta cattaaaata
    12541 tacacaatca aattctgttt gttatgctaa agatggacaa gtaatagggg taggtgcagg
    12601 tcaacaatca cgtattcatt gtactagact tgcaggtaac aaagctgata cttggtatct
    12661 tcgtcaacat cctaaagtat taaacttaaa atttaaaaag gatataggtc gtccagatag
    12721 agataacact attgatgtat atctttctga tgattatatg gatgtgcttg ctgatggcat
    12781 atggcaaaac ttttttgaag aaaaaccaga gcctctaact ggagaaggaa aaagagcatg
    12841 gcttaaaact ttaacaggag tagcacttgg ttcagatgca tttttcccat ttggagataa
    12901 tatagaacgt gcaaaaagaa gtggggtaag ttttatagca caaccaggtg gttctattcg
    12961 tgatgataat gttatattaa cttgtaataa gtataacata gtcatggcat ttactaagaa
    13021 tagattattc catcattaaa atactgaaag tataaagata atatagatta agtaaaaatc
    13081 tacaacaagt tttgttgtag atttttttat ttgctgtata attttaaata gaactttatt
    13141 tttagatatt caatttggag gttgatatgg ctttaaatat aagaaactat agcctattat
    13201 gtaatcaagg aacagctaaa tttaatgaag atgtagtcgg tataaatcca tttggggcat
    13261 gggttttaga tggtgctaca ggacttaatg gaaaaaattt agtgtcaact gaaagtgacg
    13321 caaggtggta tgttcagtgg tggaataggt atttatataa aaatataaat aaagaagaat
    13381 cattaaagag tattattaat actggaataa tagaagtaaa aaaagagtat gaactaagat
    13441 taaatgggtt taaggttgaa aaattagatt taccatctag ttctatagtt gttgtaaaat
    13501 ttcatgaaaa taaagtagag tattttttat taggagattg tgctttgttt attaaaaatg
    13561 gagattccaa agttataaaa gataggagta tttgtaaatt tgataatact gtatttgatg
    13621 aaatgagtaa actttctaac ttggaagaga tggcatttga tgagattaga actagtgtta
    13681 tggatacaat agtaagtaat agattgaaga aaaatacaaa agatggctat tggatattgg
    13741 attttgatga ggaagctgtg gaaaattcta tatatggata cattgaaata aaaaaagatt
    13801 ttcaattgat gctaacgagt gatggtttta caagtgcatg tgatagatat aatctaataa
    13861 aagaagaaga attgatacgt atagcagaaa aatttggtat aggatatata cataataaag
    13921 taagggattt tgaagataat gactataaag cggttaaagt gccaagattt aaagtaaaag
    13981 atgattcatc ttgtttatat ttagatatat ataatgatta gactgtataa aactatttaa
    14041 ttttagaaag gaggcaagtg aaaagtgaaa attcttcata taataacaca aaaaccaaat
    14101 agtacaggta gtggtatata tttgtctggt atgataaaag ggttcgaaaa aatcggtcat
    14161 aagcaagctg taattgcggg tatagatgta aatgatgatg taaattgttt tccaagtgaa
    14221 gtaagttttt atccagtaaa gtataattgt ggggagttaa attttcctgt tgtaggtatg
    14281 agtgattcta tgccatatga aagtacaaga tataaagatt taaatataga catgataaat
    14341 agattgaaat atcaatttaa agtaaatata gataaggcta tgaatgattt taaaccagaa
    14401 cttataatat gtcatcattt gtacctttta actgcatttg ttagggaaat ggtaaaagat
    14461 ataaaggtta tgtctatttg tcatggaact tgtttaagac agttaaatac cattgattta
    14521 gagaaagaat acataatagc aaatataagg aaattagatt taatatttgc tcttcatgaa
    14581 aatcagaaat atgatattat aaagactttt ggagtaagtg aaagtaaagt agttgtaatt
    14641 ggtagtggtt ataatgatga tatattttat aataaaaatt ataaaataaa ggatgataaa
    14701 ataaaaatag tatttgcagg taagatatgt aaatcaaagg gactgattcc atttataaaa
    14761 gctatatcta aattaaaata tagtaaagat ttaatagaag tcaattttgc aggtactgga
    14821 agcgatatcg aatcatataa tgagatagtt aaactggcaa gtaagtctcc atttaaaatg
    14881 aatttcctag gaaagttaga acagagagat ttagctgagc tattcaacag gtcacaaata
    14941 tttgtgttac catcatttta tgagggatta ccagttgtag ttttagaagc tttatcttgt
    15001 ggcacagatg taatcactac tgatattctt ggtgttaaag agtggattgg tagtgagatt
    15061 aataattctg gaaagataga atatgtttct ctacctttta tggagaaaga aggtattcca
    15121 aaagatgaag agttatatga ttttgaaaat aatttgtata atgcaataga ttctaagata
    15181 caatctttat tgaataactc aaataagaaa acatctgtag atatgtcaaa aaaaacgtgg
    15241 gatggcttag catatagaat aaatgaagtt attttaatgg atgaattgtg tttagtctaa
    15301 aattatttaa attataaaaa agtgtaacta tttttacact atttttaaat gattttatat
    15361 tatactaata ctaaatatat ttgttttagg gaggtaattt atgaggatta gtaaaaaggt
    15421 attggcgtta ggtatttcag cattactgtt aagtgttagt tttccaacat caataaacgc
    15481 actagataag attgaaaata ttcaaggagt agataaatat gaaacagctg ggcttatttc
    15541 agataagcaa gattttacaa cagcagttct tatcaatgca gattctacaa tggtagatgg
    15601 gattgctgca agtggtcttg caggagtaaa taatgcagct attttattaa ctaataagga
    15661 tgatatacca gaagcaacac ttcaaagact gaatagagtt actaagatat atgtaatagg
    15721 tggagaaaat tctataagta aagatgtaga aaaaatgtta cttatgagaa gaatgcaagt
    15781 tataagaatt gatggtgtag atagagtaga tacaagttat aaaattgcag gcgaaataga
    15841 aaaaattaaa aacagtgata agatgttttt agtaaatgga tttaaggatg aagctgatgc
    15901 agtaagtgtt gcatctgttg cttatagaga tggagctcct ataatattga caaaagatat
    15961 accttcagca gaagaagaca cagacttaga cccatggttt ggagtttctc ctgttccagt
    16021 atatgctatt ggaggagagt ctacattaag tgattacata gtgagcagat atagagcaac
    16081 tagaattggt ggtgttgata gatatcaaac taataaaaat gttattgaaa agttctataa
    16141 tggagcaaaa gagttctata taacaagtgg agacgattta gtttatgctt tagttgcatc
    16201 accacttgca aaaaatgctc ctgttgtttt agtttcaaat aaaagtgata agagtatatt
    16261 aagtggagct agtaaagtaa cagcaatagg tataagtgat aagagtatta tagagcaatg
    16321 tttggatgct gtaaagaagt aatggagtgt tattagtaaa atgaatatac acattgaaaa
    16381 ttagtagatt gttcatttta taatggtata aaatatatgg gaagaggcta tcaaatggag
    16441 ataagcctct ttttcattgt taaaattatg aaaagatact ttattttata taaaaaagta
    16501 tcttatgaac taaatgtcta ttttgagata ctatctcccc ttcttatatt atattatttt
    16561 ttatatggaa taaatttcat aagtattatc ttcctttaat ttttctaacc aaaccatctc
    16621 taaaatatct agttcttcta aataatcttt ctctgttttg ttatcatcat gttttataag
    16681 ttctaaaact tcaaatgtaa atgctttttc accatatttt ttccattcat tatttaattc
    16741 ttttatcata catgagccag caccaagctg aaatttgaga gagttaaatt tgctttttat
    16801 gtcattactt tttccaaggt aaatcttttt agtaatatca ttttttatta tgaatacacc
    16861 tgtgtcaaat ttcatttctt tgtataattg ttttaattca cgttttctat ccatgatttt
    16921 agatacctct ctttataatt gatatgtaat atgtaagtgt aaaaatatat tacatatcaa
    16981 ttataaagag attaatttta tatgtaaata gtttttataa atttaattat gaattagtca
    17041 tcaataaaca agaaatttag ctgtagaaat ccattataaa ggctattata aattttaata
    17101 tgctaaaaat ataaaaagaa tagttgacag tgtagaaaat atggaataaa ctaaaagtgt
    17161 aatagtaata tgaaattata tattacattg aaaggtgtga atgattatta tgaataaaaa
    17221 aatagaatta atagggaatt ttgcaagtga ttggattagg tatagtgatt atgaatataa
    17281 aattactgaa gaagatgaat tatatatagt tccaacagaa gatgctgtgt ttaccatgta
    17341 taacccattt gatgtagcag atgatataat agtagatata attcgcatag gacaagaggc
    17401 attacaagat atatcaaaag agacaaaaga aatgaaacta aagaaagaag tacttgaatt
    17461 tgtaaaaaag tatggattat tgggtttaat atattcaagt gtatataata gagatatagt
    17521 tggagaagaa agagtactga tgattgaaaa gaattatatt acaaaagaga atatattgag
    17581 tacagatgaa tatgtaaaca tgtttatacc atttgcaagt gatgaagatg tgtattttaa
    17641 aaaatataga aggggtatag atgtatcaaa gagagaagaa tctccaaagt tttttggaaa
    17701 gagaccattg attttagatt tagtattttc aaagttctac actgaacaac tagattggat
    17761 tgtaagtttt gctaaagata tgtgtaagca ttttaatcaa atttgtgtat ataaaaatac
    17821 atctaatcta ttaactgaaa gtgttactat tatgtctgga gggtttaatc ctcaaaagat
    17881 aggattttct ataagccaat tagataaacc aattattgca tgggagtttg attctttgaa
    17941 aacagctatt gagactatct atgcctttgc aattacaagt gaaccttctt ctttaaataa
    18001 atgcaagtac tgtggtaaaa tttatattcc tacaaattct aaatctcaat actgttcacc
    18061 ttcttgtaga aattgctcaa atgtaaagaa aagtagaagt agagccaaaa aagataaata
    18121 aaattaataa atatatcatt gtttagattt tagtaaataa ctactgaatt aaaagttgtt
    18181 atagaaagtt atatatctaa atgatggtat ttttttgttg agaaaattga aaagtttaat
    18241 tgagatagta attttgagtt gacaaaaacc acttttaaca ctactattat aagtggttgg
    18301 caaaataata tgtactaatt taagtatagc ataaaaaaca aaaaaagtca atgaaaaaaa
    18361 taaaaaagga gaatttaaaa atgatatcac ctattatttt gagttctata aatcagaatt
    18421 taaaggaaat agaaagaaat gaactgcttg aaactaatat agaatctgga gattatggcc
    18481 tagctctttc tgaatctgat gtaaaagata taataaattc gagagataat actttaaagg
    18541 ggtatggaag aatagaatta gatataaaag ttacaaaaca gttaatagaa aatatatata
    18601 catcacaata tacaaatgtg gacaattatt tagaggctat taatgatatg caagaaattt
    18661 tttattattt aaaaaatgaa actgatgaca agatatgtga tgatgagatt atagaaatac
    18721 tgggtgaatt ttatgaaaaa ttttcaggca atatggacaa tgtaagagga gaagcagacg
    18781 aatttgcaaa gaaatttaaa tttggagaag tttaatatat gataggagag attttgtatg
    18841 ttaaataatt taagtaatat taatataaac gaaaataatt taataaagaa ccaatattcc
    18901 atatctctac ttaaggaatg tctaaattgt aaagtgatag atgaaaggga agtatataat
    18961 atacaacaag aagtatctct aatacttatg gatttgatta aaaaatatac aaatggtcaa
    19021 agcacatcag taaaaacaga agttgccgaa aaactgttga tttcaatatg gtatgctatt
    19081 gatgcatata taaataagct tggagatata gaaaaaagag ttgtggagtt gactgctaag
    19141 aatgttaaaa aagtgtacct tggaggcatt gaaatattag aggaagagtt agttaggcta
    19201 aaagattttt ataaactaat gatgagtaga aaattggata ctaattcaat agcatataat
    19261 gataccttga tggagttatc aagtttcttt aaaagttata ttgtaaaatt tgaagctcag
    19321 gacgttccag taagtataga ttatccattg gcactagatg atatggatgt taagggtatt
    19381 tattatgtga agaattatat tgagagtata gatatagaaa atagattttg taacctattt
    19441 aagaaaaaag atagagaaaa attattttat gactatgggg tgacttataa aatagattgt
    19501 gatgttatac ttgtaaattt atttgaactt attataaata attgtatttt ttctactatt
    19561 ttaggaaatg aagtgactaa tttagaaatt tcaaaatatg agtatgaatt tttagaaaaa
    19621 caatttaaaa atatgtacaa taatattact gaagataaag ttataggctc tgaagaaagt
    19681 aatataattg aattgattga agtagatgat agttttaaca ctgaagtaga tagtaatttg
    19741 gattataatg attttgaaga aattaacaga gaaattagaa taaataaaaa aataacttta
    19801 ctacttatgg aagcaattga agtattaata aaaagattaa gcatagaaga tgaagatgta
    19861 ataagatata ttaaaaaata tgaaaagata tttattgaat ctgtgctaag ctcaataaaa
    19921 agtaacactt ttaaaagtat ggtaactgtg agtaaaaata aaaatgaaca cttagaagat
    19981 tatattgttg atgatgaaag taaattggat gatgaatcgt ttagagagat attcaatgag
    20041 atattagata gtacatctat aattgaaaaa ataagaataa taaaggaaaa tatcaatgct
    20101 aaaaaagact ttatcgatat tcttgaatct gaatgtttat ttggagaaga gtatttaatg
    20161 ttgtttgcat cattaagtga attagaattg gcaatattgg gtagtgtagt attttatgaa
    20221 gatattagaa tgagagaaat taatatatta gaatttatgt taaatgagaa aactgaaact
    20281 actttatgga agatagagta cattaaattt atgaagaggc aaagtgaaga taagatatac
    20341 tccatagaag agcatatgaa taaaattaat taacaaaaaa ttgtgaataa atagaatgtt
    20401 agtatataat ataatctgta aagcatatca aaaatacata tatttggagg aaaattatga
    20461 aagagtatat cataaataat gttgaagaaa taagagaaga attaattgat ttatctaaga
    20521 aaatatggga aaatccagaa ttagcctttg aagaaaagta tgcaagtagc attcaaaaag
    20581 aatacctaaa gtcaaaagga tttaaaattg aagaagtaga aaatttacct actggattta
    20641 tagcaagttt tggagatggt aaacctgtga ttggcatact tggagaatat gatgctttac
    20701 cagagctatc acaatgtgta agtgcagaaa gaaagccatt ggtagaagga aaagctggac
    20761 atggatgtgg gcataacctg ttgggtgtag caggtgtagg agcagttgtt tctataaaaa
    20821 aattaataga agaaaataaa tttaatggaa caataaaata ttttggttgt cctgctgaag
    20881 aagaaggtgg aggaaagaca gttatgtgta taaatggctg ttttgatgat gtagattgtg
    20941 catttacatg gcatcctttt gatataaatg caccttggag aggaggaagt ctggcaaact
    21001 tatctgtaaa atttaaattt aaagggataa cagcccatgc agctcaagct cctcataatg
    21061 gtagaagcgc acttgatgct gttgaaatta tgaatgttgg agctaattat ttgagagaac
    21121 atgttattga ctctataaga atgcactatg ttataactaa tggtggtgga agacctaatg
    21181 tagttcctgg atttgctgaa agttggtact ttattagagg taaaaaagca aaggatgcag
    21241 aacacgttct tgatagatta ataaaagtag ctcaaggagc agcaatgatg acagaaactg
    21301 aaatggagta taaggttaca gatggaatat atgactatat accaaaccaa tgtttgactg
    21361 atttagttta tgacaatatg gtttttgttg gttgccctaa aaatactcct gaagaagaag
    21421 aatttgcaaa aaaattgtgt gatactctta ctagagaaga aagattaggt gtagcaacat
    21481 cattacaaaa tgataaatct attgtagaaa gctatataca caaggaaata gttgacggtg
    21541 acaaagataa aggactagct ggttctactg atgttggaga tgtaagttat gtaataccag
    21601 tggctcaatt tgcaatggca gcttggcctg ttggaattgc aagtcataca tggcagtcat
    21661 gttcatcagc aggttcaaat ataggatttt ctgctatgat aaattcagct aaagtactgg
    21721 cttgtagtgc ttatgatgta tttatggata ctaaaattat tgatgaagca aaaattgaat
    21781 ttgataaatc attagatgga caaaaattta aaccattggt ataattttgg taataaaata
    21841 tttctggggg gaatagctat gagagaaaaa gttgaaaaag tgcttgagga aaagataaaa
    21901 ccagtattac aaagagatgg tggagatgta gagcttatag atgtaaatga aaatggtgtg
    21961 gttttagtta gactacaagg ggcatgtagt gggtgtccag gagcgactat gacaatcaaa
    22021 gctattattg aaaatgtttt ggtgagtgaa gttccaggag taactcaagt attaggtgtt
    22081 taatagttag cgtttattaa atgtatgtta tacataagta tttaataaag aagtaaaaaa
    22141 aatagtgaag caatatatat gaaaaagtat gagaaagata ataaaacatt atagaaataa
    22201 tgaaatattt catatgtata tgaagaaata agaaaaaata gtgaagcaat atatatatga
    22261 aaaagtatga gaaagataat aaaacattta tagaaataat taaatatttc atatatacat
    22321 atgaaaaaat agtaaaacaa tatatatatg aaaaagtgtg agaaaataat aaaatactat
    22381 agaaataatt aaatattcta tataggtatt aagaaacatg aaagaaataa tggagtatta
    22441 taaataaata tgtaaaagtg tgaaagaagg atgtagataa atttgtctta tacaaattta
    22501 cctacagtat ttcttacaca ctttttattt tactatccag ccataccaat aaacatacct
    22561 ataaaatatg gaactaacca tatagtccat acaactatac taaacttatg aaagaatttt
    22621 ttcttttcct catcatcttt gtataggaca aaagtagccc aacttgcatg aaaaagcata
    22681 agtacaattg caagaagacc tgtaatacta tgaaggtttt gtgataaagc agattttact
    22741 tcaaaagtat ggctgttggc tatgttactc attgtaaatg ttcctaaagt atcaaatata
    22801 aaaccaagcc aaaatataat tacatgtttc ttttttaaaa tttttgcctt tctttctcca
    22861 aatacaccta tagtgtagaa aattaaagct gatgttataa atactattgc aagtattaat
    22921 ttataattca taattatctc tcctttactt ttgccaatat atttctaaga ttttttacta
    22981 agtcactcaa ttcgttttca tcacaatttt taaaaatatc atcaaaactt tcttgcattt
    23041 taattttaaa atttgtggca aattcaaatc ctgttgttgt aaacttaacg tatgtatttc
    23101 ttttatcatt agatttcttg aatttttcta tatatccaat ctgttctaat ctgctgatta
    23161 tgcctgaaac cgtaccttta gctaaagaca tttcatcaca tagttgtgat attgtaagtt
    23221 cttgattatg agctatcagt tttataacta taatctgttg gtgtgttaat ccattttctt
    23281 taaaattttc ttctactgtg tacatagttt tagaataaag ttcttttaag agcatggcta
    23341 ttctaaaaca gtcataatta cttttcaata aaatcacctc ttaaatggtt tgcatacaaa
    23401 ctaatataat atacttttct tatatagtca acctaaaatt ttataatttt atagaaaata
    23461 atgaagaata gaatataaaa attttatttt aggtataaat aaaataattt gatgaaattt
    23521 taacaatttt taaaaagttt gtttacacag ttaataaatg atgctaaaat taactcatag
    23581 ataaatatag aaaatttaat tttgtttaat gataatggaa ccacgaaggt tttaacgtta
    23641 ctttacgttt gcttttatgt ggtttttttt attgcaacaa aggggggttg gggtttgtta
    23701 aaggatatat tgaaaaagtt gttgcagttt attttagtaa tgtttttatt atcttttatt
    23761 gttttttaca tggcaagact tgctccagga gacccattaa tctcttacta tggggatgga
    23821 gtagaaagaa tgagtacaca agaaaaagaa aatgctatga aaaaacttgg tttggatgaa
    23881 ccaatataca gtcaatatat aaaatggatt tcaaatgcat caaaagggga atttggaatt
    23941 tcatttaaat ataaacaaaa tgttacttct gttataaatg atgtctatat aaacactata
    24001 atattaggtg gttcaggata tatacttacc tttgtgctag ccttattgtt aggaatattt
    24061 tgtacattac atgaagataa gctcattgat agaatcatat gcaaattagg aacaataacc
    24121 aactgtattc catcattttg ggttgcctta gtactcatac ttatatttag tataaactta
    24181 agtatacttc caagtagtgg tgcttattca atgggagaag agtccagtat attaagtagg
    24241 atatcacatc taatcttacc tcttacagta cttatattaa gccatctatg gtattacaca
    24301 tatatgataa gaaataaatt actagaggaa ataagagaag attatgtgct tttatgtaaa
    24361 gcaaaaggtt taaataatag aactattgtt tttaagcatt gcctgagaaa tataatgcca
    24421 tcatatatta gtataatggc catttcgata cctcatatac taggaggaac ttatgtagtt
    24481 gaaaaagttt tttcttatcc tgggttagga acactttgtt ttgaaagtgc aaagtatcat
    24541 gattataata tgttattagt tttatgctta ataacagggg ctttagtagt atttgggaat
    24601 atgttagctc aaattataaa caataaaata gaccctagaa tgaaatatga tagaggtgat
    24661 actaatgaag ccacaatata gtgattttga aattgtagga gaaaattata ttttagtagc
    24721 agaagatgaa catatagaaa caaagaaaac cttatctaaa aaaattaaag aattaccata
    24781 tatatcaatt attattttat caatcatagt cattggaagt gtattctcat cttttataat
    24841 gacacatgaa ccaacataca tggatttagc aagttctaat ttagctccaa ataaaacttt
    24901 tttatttgga acagactcaa tgggtagaga tatatattct atgatatggt atggaggaaa
    24961 aatatcttta tttataggac tattttccac tgtaatatca actgttatag gaattgttta
    25021 tggtagtata agtggttcag catctgaact tgtagatgat gcaatgatga ggtttacaga
    25081 aatcatactt agtatacctt caatattaat tataatattt gtacaagcta tacttggaaa
    25141 ttcaaatcca gtatctatgt ccatagtaat agggataaca agttggatga atatatctaa
    25201 gatagtgaga acagaagtta gacaaataaa aaatagcgaa tacatactag cagctaagag
    25261 catgggagga ggattcttct atgtattaaa gcaacattta cttccaaatt ttgtggcatc
    25321 aataatgttc atggttgtaa caaacatagg cgcagctatt ggtactgaat cgacacttag
    25381 ctttttagga attggtttac caatagaaat tgtttcttgg ggaagtatgt tatctttgtc
    25441 agaggaagca ttactttcaa atagatggtg gattatactg attccgggta tatttttggt
    25501 taccacattg gtgtgtataa caaatatagg taattatata agaaagaata ataataaaaa
    25561 atctagtaat ttataaatca gcatttgagt attaaataag caaatactga ggtatttgaa
    25621 atatctattt aaataaatgg ggtcaaagct ttgaaaaata ttttataaaa agcaaaaggg
    25681 ggagcatcat gaaattaaag aagttaaaag ttttaagttt agtaatgata cttagtctaa
    25741 tggcaggttg ttctagtgga ggagacaaag ataagaaggc agatacgcct aaagatggaa
    25801 aggtacttgt ttatggaagt aatgactata caagtataaa tcctgcacta tacgaacatg
    25861 gagaaataaa ttcgttaata tttaatggat taacagctca tgatgaaaat aataaggtgg
    25921 ttccttgtct agcaaaggac tggaaatttg atgaggcaac aaatacatat acttttaatt
    25981 taagagatga tgttaagtgg catgatggag aaaaatttac agcaaatgat gttaagttta
    26041 caatagaaac tataatgaat ccagataatg cttctgagat agcatcaaat tatgaagata
    26101 taacaaaaat tgatgtggtt aatgataata ctataaaaat tactttaaaa gctccaaata
    26161 cagcaatgct tgattattta acagtaggag tattaccaaa acatgctttg gaaggtaagg
    26221 atatagctac tgatgaattt aatcaaaaac caataggtac tggaccattt aaacttgaaa
    26281 aatgggacaa aggtcaaagt ataacacttg ttaagaatag tgattatttt gtaaaagaac
    26341 caggattaga taaagtagtc tttaagattg ttccagatga taaggctaag gcaatgcaat
    26401 taaaatcagg agaattagac ctagctcaaa taactcctaa agatatgtct aactttgaaa
    26461 aagacgaaaa gaattttaaa gtaaatataa tgaaaacagc cgactataga ggtatattat
    26521 acaattttaa ttctaaattc tttaaagata aaaaagctaa aggattacca aatgctttaa
    26581 gctatgcaat agatagaaaa gcaatagttg acagtgtatt attaggacat ggtgtaccag
    26641 catattcacc tttacaaatg ggaccatata ataatcctga tatagaaaag tttgaatata
    26701 atccagaaaa agctaaacaa gaaattgaaa agctaggttg gaaattaggt tctgatggaa
    26761 tctatgaaaa agaaggtact aagttagctt tcgagataac agcaggtgag agtgaccaag
    26821 ttagagttga tatggctaaa atatgtgcac aacagttaaa agaaattggt gttgatgcta
    26881 aagctgttgt tgtaactgaa acagattggg ctaatcaaga tgctcattta ataggttggg
    26941 gaagtccatt tgacccagat gaccatacat ataaagtatt tggaacagat aaaggtgcaa
    27001 attacagtgc ttactctaat cctactatag ataaaatact tcaaaaagca agagaaacag
    27061 aagataaaga tgaaaaatta aagttatata aacaattcca agtagaaatg actaaggata
    27121 tgccttatac atttattgct tatatagatg caatatatgt tggaaaacca aacataaaag
    27181 gattaacacc tgatacagtt ttaggtcatc atggtgtagg tatattctgg aacatagctg
    27241 actggacaat tgaataatac tgaaattaat tagaaacctt agggataaaa atatatccct
    27301 aaggtttgaa tagcataggg gttgatggtt tttggaacat ttattggagg ttaataatct
    27361 atctgtaagt tttaaagtag aagaaggaga agttcaggct gtaagaaatg tatcttttaa
    27421 tctaaaaaaa ggtgagacat tggctatagt tggagaatct ggttgtggga aatctgtact
    27481 gtgtaagagt ttgatgagga tactcccata caatggatat attaaaaatg gagaggtttt
    27541 acttaaatca agtgatttgg ttaagaagtc tgaaaaagag atggaagata taagaggaaa
    27601 gaatatatca atgatatttc aagaccctat gacatctctc aatccaacta tatcaatagg
    27661 aaagcaaatt gcagaagctg taatcattca tcaaggtata agtaaaagtg aagcaaaaaa
    27721 gagagccata gagcttattg aattggttgg aattgataat cctgagaaaa gatttaaaca
    27781 atttccacat catttttcag gtggaatgag acaacgtata gtaatagcta tagcacttgc
    27841 ctgtaatcca gatgtattga ttgccgatga acctacaact gctttagatg taactataca
    27901 agctcaaata attgatttaa taaaggattt acaacataaa ataggtttgt caataatatt
    27961 tataactcat gatttaggag tagttgcaac tatagctgat agaatagcag ttatgtatgc
    28021 aggaaagatt gtagaaatag gaactgtaga ggatatattt tatgacccta gacatccata
    28081 tacttggggg ttgttgggtt cattacctac tttagattcg caggatgact atttatataa
    28141 tatacctgga atgcctccaa atttattgaa cccaccaaaa ggagatgctt ttgcaataag
    28201 gaataaaaat gcacttaaga tagattatga aaaagagcca ccaatgttta aaattaatga
    28261 tacacatagt gcagcaactt ggttattgca cccagatgca cctgaagtag atgtaccagt
    28321 tagagtaaat tgtggaaggg tgatttctaa tgaatagaga aaaaatactg gaaataaaaa
    28381 acttaaagca atattttcat ttggacaaaa gtactactgt aaaagcagtt gatgatataa
    28441 gttttgatat atataagggt gagatatttg gattggtagg agagtcgggt tcaggaaaat
    28501 ctacaactgg taaaactata ataagactac atgaatctac tggtggagaa gtaatttaca
    28561 aaggaaattg catatcagat aaaaaaacgt acaaatttat aaaaaaagat gtaaacaaaa
    28621 gtatgcagat tatttttcaa gattctactt catcattaaa tccacgtatg acaattgcag
    28681 atataatttc agagccacta aaaattcaag gtatctgtaa aaataaaaca gatagaatga
    28741 ataaagtata tgagatgcta aagctagtag gacttgatag aagttatgca aataagtatc
    28801 catctgattt ttcaggtgga caaagacagc gtattggcat agcacgagct ctttcagtag
    28861 acccagaatt tataatagct gatgagccta tagcttcttt ggatgtgtct atacaagcac
    28921 aaatagtaaa tttatttaaa aaattgcaac aagaaaagaa tttaacttgt ttatttatag
    28981 ctcatgattt atctatggtg agacatatta gtgaccgtat aggagttatg tataatggaa
    29041 aattagtaga attggcagat tcaaatgaat tgtataataa tcctattcat ccatatacaa
    29101 aatcactact ttctgcaatt cctgttcctg accctagata tgctaagtca agaaatagaa
    29161 tagagtataa ttctaatgga tatgattgtt caaatgaaaa gttattaagt tggattgagg
    29221 tttcagatgg acattttgta tattcttcta aatcagacat aagtaaatac caacaaaatt
    29281 taaaagttgt ttagtataaa aatacttgaa caggtattta tttgaaatac aaactaaaac
    29341 cctatttttg gagaaatttt aaaactactc caaaataggg ttttttattt ctacttttca
    29401 aatataataa attcaaatat aataaaatta aaaacaagta aagtatgttg ttaagaaagt
    29461 actataaaat taaaaatagt aatgtagaaa aaatgagcaa taatcttatt ttttctacaa
    29521 taattttcta taatttaaag taaggaaagt ttgataaatt ataaccttag ttaaagaata
    29581 agagtttatt aaaaaataaa gtgtgtatag gggttttagt taataaaata ctataatgta
    29641 ggggagcttg taatgatata taaaaaagat aaagtaatga aagttttaga atcatcatat
    29701 agggaaaatg aaaaagggat tacagctaac caattatcag aaaagacagg aattgcaaga
    29761 aacaatataa gtacatattt aaaccaatta ttcaatgagg gtatggttac gaagataaaa
    29821 ggaagacctg tgtattatat ccctgcaaat cttaacctta acaagaatga attgcttgat
    29881 acacaaagtg agttgcttgg cataaaaaaa ggaacaaaag tagaaaacaa aataaaaaaa
    29941 gatagttttg aaacactaat aggtaaagaa catagtttaa gacctataat agaaaaatgc
    30001 aaggtcgcaa tgctctatcc tacaaatgga cttcatacta ttatctatgg agaaacagga
    30061 gtaggaaaga gtatgattgc tagatatatg tacgattatt ctatagatag tggaattaga
    30121 aaaaataaag ctccttttgt aacatttaat tgtgctgatt atgctaataa tgcacaatta
    30181 cttatgggac atatttttgg ggtagaacaa ggagcttata caggtgcaga atcttccaga
    30241 aaaggtcttt tggaaattgc aaatggaggg atactatttt tagatgaaat tcatagacta
    30301 ccagcagaag gtcaagaaat gttgtttact tttatagata agggaacatt taaaagacta
    30361 ggagatgcaa cgaaagaaag agagtctaag gtattaataa tatgtgctac tacagaaaat
    30421 ccgacatcaa cactattaga tacattcaat agaagaatac caatgaaaat agaaatacca
    30481 tcactgagag ataggacaat gattgaaaga atggaattag tcaaaaattt tttcaaggaa
    30541 gaatcaaaaa gtatttctat ttcaataaaa gtacataaag aaataattaa atcactatta
    30601 ctttatgatt gtaaaaataa tgtaggtcaa cttcaaaatg atataaaatt agctgttgca
    30661 aatggatacc taagatataa aagagataat aaagaaccag tttatataga gaaaaaatat
    30721 tttgataaat ctataaatga agtgagtgat gattatagag agaagtctat taaagcagat
    30781 gaagttataa cacatggaat agaatatttt gtatttacgt cattaggaga agaagaagtt
    30841 attaactaca atgatataaa tattattaat gcagtaaata ctaatcttaa taaatctgta
    30901 gaaatgaata tagcagatgc ttccctattt aataatgtta agtttaaaag catgtgtgaa
    30961 tcaataagac aaattattaa agaagatgaa gaaatagata taagtgaatc aatatttaag
    31021 tcaatggcaa tttatataaa aagcgtattg gataaaagta gctctacaaa caacatagat
    31081 ttgaatcaaa ttagaagaaa taacagaagt gaatttaaaa cagcattaaa aatagttgga
    31141 ataattgaaa atgaatttga tttattttta tctatagaaa ctgtagcata tattacatta
    31201 ttcatagtac aagctaaaca agatgaacaa aataaaatag tgaataacat taatattata
    31261 gttgctatgc atggagaaac tacagcaagt agtatggtaa aagcagttgg tgatattatt
    31321 gtaaagtgca gtgctatttc tttcgatatg aagttagata aaagctatga tgaagttatt
    31381 gtagatttta aaaatttaat taataatata gacaataaag atgtattact atttacagat
    31441 atgggttcat taaactcttt tgatgaaatt ataaagaaag aaaaaaagtg tggagtaaga
    31501 gtaattccta tggtgacgac attaactgtg ttagaagcag ttcagaaggc caatatggga
    31561 ttacctttaa atgacgtata caactctatc actaacacga gaaagtacta ttttggaact
    31621 aatgaaattc aaaataaaga aaatctgtct aaaacaatta ttatagcatc acatgtttca
    31681 gaaggtgtag ataataaaac aagaaaaata ttagaagaaa agatgagtag gtacttagat
    31741 ggaatagata ttatatctgt cccatataaa acagaaaaag atttaagttt aaatattacg
    31801 aaacttaaag aaagtagtaa tattgttgca gtaatcaatg aacaaagaat taatattaga
    31861 ggaattgact atattagcaa aaaagatata gataaagatg aaaatatcaa taaattaaaa
    31921 aatattataa agataagtat aggttatgat gatgtagttg aaggtttaaa gacatcctta
    31981 aaaagctcta attataatag gatatttaaa gatataaaat atgtgtctga tgaattgttt
    32041 ttagtattta atatagaaaa gaaatacgat aaagtaattg gacttatgat gcatttagct
    32101 ttcatggtag atgggttgat tggaaatact agagaaattg aaaagcttga taaagaaaaa
    32161 acacttgatt atcacaagag tctaagcaaa ataaaagata tagtatctca attagataaa
    32221 aaatataata tagaaattaa tgaaaaagag tgctatcaaa tattattaat attagaatat
    32281 gcagaaataa tcgaaaaaga ttaccaatga gtataaaaac ttatttggta atttttttta
    32341 gtctaaaata atattaatat tagacacata taaatatact tagacaaagt atctaagttt
    32401 tgatgataaa aatgattgaa ataacagtgt tttaaagtgt ctaaaaaaac tggcataata
    32461 cttgcttata ttattaaatg agcaatataa ataattaaaa tttaaataaa aaggagtaaa
    32521 taatatgcaa gataaaatat taagagataa aaaggcaaat gacccatggg caagaatgac
    32581 tacaagaaac ggatttagtg cagacgaaat aatatcgtca tttcaaaaag ctataagaag
    32641 aaatatggtg gaagaagctt gtgaatttgc ttatgaacta tatatatcat caccagaatt
    32701 agaagataag ctatggagaa ggatacttac aatatcagtt gaagatatag gaatggggga
    32761 tccatcagct gtaataatca taaataattt aaatcaagta agaaaggaat attcatatgc
    32821 agatggagac agacctttat ttttcataca tgcaataaga tatctttgtg catgtgagaa
    32881 agatagatca agtgatttat taaaaaatat aattataaaa ggatttgcaa tgggtaaagt
    32941 tccagaagtt atggacgtgg cacttgacaa gcatacatat agaggattag aaatgggaag
    33001 ggattcattc cactttttaa atgaagctag tatagtaata ccagaaaaag aagtagataa
    33061 tgattataaa gaaagatact taaaaatatt agaaaaatat aagcaagaag aagttataga
    33121 tacggctttc aagtttaatc attggcagta ctaagaatta gagtaaatat taataagaat
    33181 taaaataaaa taataagaat taaagtaaaa actgatagga attagagtaa gaattggctg
    33241 ataaaaaatt agaaaataaa agaggttaga tattgtagga gggtaattat gaatatttta
    33301 ttagtatgtg caaatggagc ttcaacaggt gtacttgtgg aaaagatgaa aagtttttgt
    33361 agtgagcatg aaaagttaaa aactaaaact ataaatatag aggcaacatc atttgaaaat
    33421 ttaaaatcat acattgaagc taatgataca gatgtagtac ttgtagcacc acaaattagg
    33481 tttaaggaag atgatgtagt tgaagcttgt aagaattaca aaatagcagt tggtttaata
    33541 gatactaagc attatggtcg tatggatgct ccttctgtta tgaagtcggc aatcgaatta
    33601 tataaaaata gataattggg gggaataaaa atggaagcac ttcaaaataa tttaagaaga
    33661 tttcttcttc caatagcaca aaagattgaa aaacaaaggc atcttcaagc tataaaagaa
    33721 ggtatgataa gcattacccc aataataatt gttggttctt taagtatgtt atttatggca
    33781 ttaaacaata tgttacctga aggaagtgca aaaacattat tatctgaaaa tatggataca
    33841 ttacttatcc ctaataaatt tactatgagt ttattatcta tatattcagc attttttata
    33901 gctcaggcac tagctaaaaa atataatctt aatcatgtag aaataggtat gacagcagtt
    33961 gttgcacaac ttgttgtatg tggacaagta gtagatggtg tattagatac aagttattta
    34021 gatgcacaag gtttatttgt aagtatatta gtagcacttt tagtagttga tattactaag
    34081 tttatgaatg ataaaaatct cgtaattaga tttccaaaag aagtacctag tgtagtaaat
    34141 aaaagtttta gaaacttaac tccaatgata gtatgtataa tgttatttac agcaatagca
    34201 gcaataacta aaaatgtctc aggtcaacca ctaccagcta ttataatgaa tttcttagca
    34261 ccagctataa gcagtgtaga taatgttttt gcagtaacta taatactatt tataactcaa
    34321 ttattatggt tctttgggct tcatggagca gcaataactt caagtatatg gatgccaata
    34381 gcagctacat atatggcaga aaatgcaaca ctgatagcag caggaggaga cccaaaatat
    34441 gtgtttacaa taggttttta ctatggtttc ttgcaagtaa ctggttcagg gataactttg
    34501 ggattagtgt accttatgtc aagaagtaag tgtaagagtt ttaatagtat gggaaaagtt
    34561 gtgattttac catcactatt tggaataaat gagccggtaa tatttggaac accaatagtt
    34621 atgaacccat atatgtttgt accatttgta tttggacctg tattggttgg agcacttaat
    34681 tttatggcat taaaagtagg attagtagga ttacctattg cagaaccacc aggcttttta
    34741 cctccagggg ttgcagcatt tttgatgaca ttagattgga aggcaatcgt attagtattt
    34801 gcaagtataa tacttatgac cttgatatat tatccattct ttaagataat ggagaaggaa
    34861 gaattaaata aaaatgcaga attagctaca acattagatg atgatagctt tgatttttaa
    34921 caagtcatta gaaggagaag gatatggtac ctgaaatgga agaaaaagta tttagtataa
    34981 tatcagaagc aggagatgct aaaagtgatg taatgatgtc tcttaaggaa ataaaaaaag
    35041 gtgactacaa taaagcaaaa caccttttaa attcagcctc agagaaaata caaacagcat
    35101 caaagcatca tttagaatta ctatcaaatg ctatgaatag tgaagatagt gggactgatt
    35161 ttttagttgt gcactctgaa gaccattatt caaatgcatt atttgctcat tctttagtat
    35221 ctgaacttgt agatatattt gagatgatgg acccaagaat taataagaat taaatttctt
    35281 gtaaatagtg cttgaagttt ggctatagtt tattaaatca atagatttaa taaatgaact
    35341 cccttttact ttaaagtact agtatttata aatttattta taaatacagt aaatttttaa
    35401 atagaaaagg agatattatt atggaaaaat tttcagtagt aatagctgga ggaggaagta
    35461 catatacccc agaaatcata ttaatgttgc tagataactt agataggtta ccattaagag
    35521 caatcaaatt atatgataat gatgaagaaa gacaaaataa ggtagctaaa gcttgtgaaa
    35581 tactaataaa ggaaaaggac cctaatatag agtatttagc aacaacatgc cctaaagagg
    35641 cttatacaga tgtagatttt tgtttagctc atataagagt tggaaaactt gaaatgagag
    35701 aactagatga aaagatacct ctaaaacatg gagtagttgg tcaagaaacc tgtggaccag
    35761 gtggaatagc ttatggaatg aggtctatag aaggtgttct tgaaaacata gattatatgg
    35821 aaaagtattc tccaaattgt tggatgttaa attattctaa tccagcatca ataatagcgg
    35881 aagctgttag aagattgaga cctaattcta gggtaataaa tatttgtgat atgccaatag
    35941 gtatggaaca taatatagca aggattgcag gactcaaatc tcgtaaacat atggatataa
    36001 gatactttgg attaaatcac tttggttggt atacttcaat taaagataaa aaaggaaatg
    36061 aacttttacc aaaattagta gaacatataa aagaatatgg ttttataaat ggtgaagaag
    36121 gaatgaaaaa tgacaagaaa gatagttggt ttgaaactaa tttatttact aaagaaatag
    36181 taaaaacaga tttaactaca ataccaagta gttacttaaa gtactatcta tttccagatt
    36241 atgttgtaaa tcattctgat gtaaattata ctcgtgccaa tgaagttatt gatggaagag
    36301 aaaaagaagt ttttggttca tgtgcattga tagaaaagca aggacattct aagggcagtg
    36361 ggcttaagat aggaatacat gcagagttta tagtggattt agctacagct ctagctttta
    36421 atacacagga acgtatgtta ttgatagttc aaaataatgg agctatagaa aatatacaag
    36481 atgatgctat ggttgaaatt ccatgtatag ttggaaaaga cgggtatgaa ccattatcaa
    36541 tagggaaaat accaacattc caaaaaggtt taatagaaca acaattagca gttgaaaaat
    36601 tagtagttga tgcttggatt gagaagtctt ataataaatt gtggcaagca cttatgctat
    36661 ctaagacagt tcctagtgca acagttgcaa aagaattact agatgattta atagaagcaa
    36721 ataaaaatta ttggccaaaa cttaattaag aataatatat ttttaaagtt cctacagttt
    36781 agtacatagc ctagttaatg tatttgtagg gactttattt atttacaaat gagatacaag
    36841 tggcaaacat agtgtatttt gcagttagga aagtaggttt agttacttgt tagttggatt
    36901 aaatttaggt acaataattt actatcaatc aatagaaata accagagaag ttgcataata
    36961 aaaaatttac acttttaaca ggatttatgt aggtgtttat agaaataaat aaatatgtac
    37021 ataaatacat aattattttt aagtctaaaa tacaagaatg gagagatggc tatgaagtgg
    37081 agagattatg ctgatgatgt aaatttattt gaggattttg ataaaactat caagcctcta
    37141 actgacgaac aaagaagaaa aaatataaac actttaattg catatttttc aaaagaagtt
    37201 ccttctaaaa tatacaattt atcaaatgat gaaattaagc ctagagatat acttagagga
    37261 cttttgaatg tatatccacc aaaagaaatt gctccagaga tacttaatat gttacataat
    37321 ttattgttga ttgaatgtga agaaagagag ttagtagatg taaatgatat agaagaagta
    37381 gaggaaggga ttgccatatg gagaggtaat ataacgaatt taagagcaga tgcaatagta
    37441 aatgctgcaa ataacaagtt attagggtgt ttacaaccat tacatctatg cgtggataat
    37501 gagatacatt catgcgcagg tcctagactt agagaagatt gtgacaaaat aataaaaaaa
    37561 caagggcatt tagaatatac tggagatgct aagataacta gaggttattg tttacctgca
    37621 aaatttgtag tacatactgt tggacctatt gtatctggtg gtcagccaag taaagagcaa
    37681 gaaaagcaac tgcttcattg ttataaatca tgtttaaata caataaaaga aattgatgaa
    37741 ataaaaaata ttgttttttg tggaatttct acaggtgtat ttggttatcc aaaaaaagag
    37801 gcagctaatc ttgctgtaag tagagttaga ctatggctaa aagaaaatcc tgaaaaaaat
    37861 ttaaaagttg tatttaatgt gtttactgaa gaagaagaag agaaatatag aagaatattt
    37921 aaataatatt atgtaacaga atcctaaaaa tact
//
LOCUS       DAEORM030000040        37798 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.040, whole genome shotgun sequence.
ACCESSION   DAEORM030000040 DAEORM030000000
VERSION     DAEORM030000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 37798)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37798)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 37798)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37798
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.040"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            81..302
                     /locus_tag="KRH23_002491"
     CDS             81..302
                     /locus_tag="KRH23_002491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat associated protein CotJA"
                     /protein_id="HHS5225769.1"
                     /translation="MGYLKEDKQDYCCEFARPYINRQIYDDTYNPKTALKRGTLFPEL
                     DLIESNNYNDWLYANPKNRVRAKKGGNMY"
     gene            302..565
                     /locus_tag="KRH23_002492"
     CDS             302..565
                     /locus_tag="KRH23_002492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat protein CotJB"
                     /protein_id="HHS5225770.1"
                     /translation="MSLNRRELLERISEYQFACIELNLYLDNNPRDKKALDSYNRYCD
                     KFTQAVCDYESKYGALTNFGYESSEYPWSWISEPWPWDKSFYK"
     gene            627..1277
                     /locus_tag="KRH23_002493"
     CDS             627..1277
                     /locus_tag="KRH23_002493"
                     /inference="COORDINATES: protein motif:HMM:NF016925.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HHS5225771.1"
                     /translation="MWIYQKTLEHPVNIRQADPRMAKYIMTQLGGPNGELAAATRYLQ
                     QRYTMPTGKSRALLTDIGTEEMAHVEIISSVLYQLIGNCTPEELKAAGLGSNYANFGH
                     GLQPVDSNGVNFTTSYINVFGDSVTDLHEDMAAEQKALATYYQLINLTDDPDLKDILR
                     FLGEREVVHYQRFGEAKREDCSKKSTVLKAHKYSTFGKILSIRKTQDVGISRPICC"
     gene            1551..2525
                     /locus_tag="KRH23_002494"
     CDS             1551..2525
                     /locus_tag="KRH23_002494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6017 domain-containing protein"
                     /protein_id="HHS5225772.1"
                     /translation="MAVFRVEKNKGYTVMSNHHLRNKELSLKAKGLLSQMLSLPEDWD
                     YTLAGLSLINRESIDAIRTAVWELEKAGYITRRQGRDEKGKMTAIEYTIYEQPQPPAL
                     DCPVLENPTADNPILENPTPDNPTSENPTQLNKELLKTNLPKKEKLNTDISSTHSIPF
                     HSLNPSPLEDAAQPPERKRTEATDAYRVYEEIIKDNIEYDYLIQDRYLDRDRIEEIIA
                     LILETVCTKRRTIRIAGDDHPAELVKAKFMKLNGEHIRFVLDCMQENTTKIRNIKQYM
                     KAALFNAPSTIGSYYTSLVSHDMYGGRTIQSARSKGIPDYTCNEGESL"
     gene            2550..2768
                     /locus_tag="KRH23_002495"
     CDS             2550..2768
                     /locus_tag="KRH23_002495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HHS5225773.1"
                     /translation="MTQKTGALIFDETADRYDIRFDVNDYYGGLHCGDCMEVFVRGKW
                     KPTRMEYGDNWYLVGIRAADLSGLRVRI"
     gene            2862..3344
                     /locus_tag="KRH23_002496"
     CDS             2862..3344
                     /locus_tag="KRH23_002496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002610294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfB family protein"
                     /protein_id="HHS5225774.1"
                     /translation="MQEETNEKTIALYIKTGKLTAQQLQKAMKALLAQMKKQHEKQKI
                     PHGKQTLKQLMKQNAGVSNIEITKDNIKAFESTAKKYGIDFALKKDSTETPPRYLVFF
                     KGRDADALTAAFKEFSAKKLTQEQKPSIRKLLSTLKDKAAALNAQREKVKKKDREVSL
                     "
     gene            3341..5128
                     /locus_tag="KRH23_002497"
     CDS             3341..5128
                     /locus_tag="KRH23_002497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015529212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirD4-like conjugal transfer protein, CD1115
                     family"
                     /protein_id="HHS5225775.1"
                     /translation="MKPELKKLLILNAPYLLFIYLFDKIGQAVRLSPGADLSGKVLSL
                     REGFSMAFANPLPSLAPMDLLIGIFGAVLIRLIVYVKGKNAKKYRKGVEYGSARWGTA
                     EDIKPYTDPVFQNNVLLTQTERLTMNSRPKQPKYARNKNILVIGGSGSGKTRFFVKPN
                     LMQMHSSYVVTDPKGTVLVECGKLLQRGGYLIKVLNTINFKKSMKYNPFAYLRSEKDI
                     LKLVNTLIANTKGDGEKSGEDFWVKSERLFYCALIGYIWYEAPEEEKNFTTLLEMINA
                     SEAREDDPEFQSPVDLMFERLEEKDPEHFAVRQYKKFLLSAGKTRSSILISCGARLAP
                     FDIKELRDLMETDEMELDTIGDRKTALFVIISDTDDTFNFVVSILYTQLFNLLCDKAD
                     DEYGGRLPVHVRCLLDEFANIGQIPKFEKLIATIRSREISASIILQSQSQLKAIYKDN
                     ADTIAGNCDTTLFLGGKEKTTLKEMSEILGKETIDSFNTSENRGREVSHGLNYQKLGK
                     QLMTEDEIAVMDGGKCILQLRGVRPFFSDKYDITKHPNYKYLSDYDKKNTFDMEKHLR
                     RRPALVKPDEVFDYYEISESDLQEDTDHE"
     gene            5121..5291
                     /locus_tag="KRH23_002498"
     CDS             5121..5291
                     /locus_tag="KRH23_002498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5225776.1"
                     /translation="MNKRIRKKKDKKITEAINGLVFIAERREQQRQAAIRQFVKRCEA
                     LYEQQRKEGLTQ"
     gene            5505..5720
                     /locus_tag="KRH23_002499"
     CDS             5505..5720
                     /locus_tag="KRH23_002499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003068281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Maff2 family protein"
                     /protein_id="HHS5225777.1"
                     /translation="MEFFNSAIDVLQTLVIALGAGLGIWGVINLLEGYGNDNPGAKSQ
                     GIKQLMAGGGVALIGTILVPLLSGLFG"
     gene            5739..6608
                     /locus_tag="KRH23_002500"
     CDS             5739..6608
                     /locus_tag="KRH23_002500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB6/TrbL-like conjugal transfer protein,
                     CD1112 family"
                     /protein_id="HHS5225778.1"
                     /translation="MESILDAINEWIKEILIGAINGNLSTMFGDVNEKVGTIAAEVGK
                     TPQGWNANIFNMIQNLSENVIVPIAGLVITYVLCYELISMVTEKNNMHDVDTFMFFKW
                     FFKAFVAVFLVTHTFDITMAVFDMAQHIVSGAAGVIGGDTNIDVTEALAAMQEGLNDM
                     EIPELLLLVMETSLVSLCMKIMSVLITVILYGRMIEIYAYCSVSPIPFATMTNREWGQ
                     IGNNYLKGLFALGFQGFLIMICVGIYAVLVGEMVLADNLHSAIFSLAAYTVILCFSLF
                     KSGALAKSIFNAH"
     gene            6651..7055
                     /locus_tag="KRH23_002501"
     CDS             6651..7055
                     /locus_tag="KRH23_002501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HHS5225779.1"
                     /translation="MAYVPVPKDLSKVKTKVAFNLTKRQILCFSVALLMGLPLFFLLK
                     DSAGTSLAAMAMIVVMLPCFLVAMYEKHGQPLEVVIKNIIQTKFTRPKVRPYQTENLY
                     ALLEKQRALEKEVSAIVKRTDKKDAGSRRKQA"
     gene            7003..9432
                     /locus_tag="KRH23_002502"
     CDS             7003..9432
                     /locus_tag="KRH23_002502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB4-like conjugal transfer ATPase, CD1110
                     family"
                     /protein_id="HHS5225780.1"
                     /translation="MSKGQTKKTREAAGNRRKLTRAEKKQIAAVIRQAKGDGKAHTAQ
                     QTIPYLAMYPDGICKVAQRKYSKSIVFEDINYQLAQTDDKTAIFENWCDFLNYFDASV
                     NVQLSFINQGSQQEQAARAIHIPPQNDDFNSIRTEYSDMLKSQLAKGNNGLVKHKYIT
                     FSIEADNPAAARARLSRIETDVLNNFKVLGVSAHPLSGYERLKVLHGVFHPAGEPFSF
                     SYDWLTPTGLTTKDFIAPSSFKFGEGRYFAMGKKAGAVSFLEILAPELNDRILADMLD
                     LETGVIVNLHIKSIDQSEAIKTIKRKITDLDKMKIEEQKKAVRSGYDIDILPSDLATF
                     GNEAKNLLQDLQSRNERMFLLTFLVVNMADTKRKLENDIFAAAGIAQKYNCALTRLDY
                     QQEAGLMSSIPLGENLIPIQRGLTTSSTAIFIPFITQELFQTGAALYYGLNALSNNMI
                     LCDRKQLKNPNGLILGTPGSGKSFAAKREITNAFLITDDDIFICDPEAEYFALVKRLG
                     GQVIRLSPTGKGMDGTPQYVNPMDMNLNYSEDDSPLALKSDFILSLCELVIGGKEGLQ
                     PVDKTVIDRAVRNVYRDYLADPVPEKMPILGDLYDELLKQPEPEAARIAAALELYVSG
                     SLNVFNHKTNVELSNRLVCFDIKQLGKQLKKLGMLIVQDQIWNRVTINRAEKKSTRYY
                     MDEFHLLLKEEQTAAYSVEIWKRFRKWGGIPTAITQNIKDLLASREVENIFENSDFVL
                     MLNQAQGDRAILAKQLNISPQQMKYVTHTEAGEGLIFYGNVVLPFVDHFPKDTELYRI
                     MTTKPEEVSSL"
     gene            9429..10388
                     /locus_tag="KRH23_002503"
     CDS             9429..10388
                     /locus_tag="KRH23_002503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-methyltransferase"
                     /protein_id="HHS5225781.1"
                     /translation="MKTDVIINRDALCALQELPSESVHCCVTSPPYYALRDYGLDAQI
                     GQEDTPEQYIDRLTAVFGELYRVLRKDGTLWLNIADTYCGTGNKGGYADPKNPKGRIG
                     QRIARNSRVTGCKQKDLIGIPWLLAFSLREQGWYLRSDIIWQKQNPMPESCKDRPTRC
                     YEHIFLLSKEKKYYYDAAAIAEPLAPTTAERYRRARSTNSKYTHEIPGQGKVQGLNQP
                     RDGGYYDDALMPTTRNKRDVWLINTVPYKGAHFAAFPPKLAETCILAGCPKGGIVLDP
                     FFGSGTTGLAAKSLDRHYIGIELNAEYCALARARIGGAGLSNS"
     gene            10376..12331
                     /locus_tag="KRH23_002504"
     CDS             10376..12331
                     /locus_tag="KRH23_002504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA];
                     GO_function: GO:0042834 - peptidoglycan binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HHS5225782.1"
                     /translation="MKQLKPRDKITQKMTRDGAVEVNETQQTAERISSREADSDFSQP
                     DTATAERVMEHLDAAHTPKANKKAVKKEQEATVLRTSTSRLKFTDEERTTPELEPYIK
                     KSEKAADKLDAAKAAIPKQKKLVKERTFEEATGKAKTRLHFEEQEKPIPGGKPHNNPL
                     SRPAQEAGIFVHNKIHSVEKDNSGVEGAHKSEELAERGARYGTRKLKQGYRSHKLKPY
                     REAAKAEKAAFKANVNFQYHKTLHDNPQLTSNPLSRFMQKQQIKRQYAKAAKKGGTKA
                     AAEATRKTAKKTAEETRKAAAFAARHPAGILIAVAALLLFIMISAGLSSCGAMFSGLT
                     NGVLGTSYTSEDSDLVATEQSYAAMENELQSEIDAIESTHSGYDEYRYDLDTIGHNPH
                     ELASYLTALLQSYTPQNAQAELKRLFGLQYTLTLTEEIEIRTTTDEEGNEEEYEYRIL
                     NVKLTNKPIASLAEELLNPQQFEMFKVYLQTQGNKPLIFGGGSPDGSPSEDLSGVEFV
                     NGTRTGNQELMELAKQQVGNVGGYPYWSWYGFNSRVEWCACFVSWCYNQAGKSEPRFA
                     GCEWQGVPWFQSRGQWGARGYENIAPGDAIFFDWDLDGVADHVGLVLGRDGSRVYTVE
                     GNSGDACKIKSYDLNYQCIKGYGLMNW"
     gene            12364..12633
                     /locus_tag="KRH23_002505"
     CDS             12364..12633
                     /locus_tag="KRH23_002505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4315 family protein"
                     /protein_id="HHS5225783.1"
                     /translation="MANNKIERINKEIAKTREKITEYQNKLKGLEAQKTEAENLEIVQ
                     LVRAMRLTPQELNAMLSGGGIPGMNATHATEAADYEEQEENTDEE"
     gene            12623..13351
                     /locus_tag="KRH23_002506"
     CDS             12623..13351
                     /locus_tag="KRH23_002506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4366 domain-containing protein"
                     /protein_id="HHS5225784.1"
                     /translation="MKNKLKKTMTALCAALILMGGFSVPAYAQGAATEPPAEDATNDS
                     NVIVEEKEETPPLTPKGNATLVDDFGGNKQLITVTTKSGNYFYILIDRAAEGEQTVHF
                     LNQVDEADLMALTETGEATKKPEVCNCTEKCEAGKVNTSCPVCATTLTGCTGKEPTPT
                     PTEQPEEPKEKGGNPGAVLALVLFVLLGGGAAFYYFKFVKPKQNVKGSTDLEDFDFED
                     YDEDEPEADTGETSEDEETEEETL"
     gene            13549..15639
                     /locus_tag="KRH23_002507"
     CDS             13549..15639
                     /locus_tag="KRH23_002507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase 3"
                     /protein_id="HHS5225785.1"
                     /translation="MILVIAEKPSVAQTIAAVLGAKEKKDGFLTGSGYIVSWCVGHLV
                     GLSEADAYGEQYKKWSYDSLPILPQEWKYTVAADKEKQFKTLKELMHRADVSEVVNAC
                     DAGREGELIFRFVYEVAGCRKPMRRLWISSMEEAAITEGFSHLKNGEAYDALFASALC
                     RAKADWLIGINATRLFSVLYNHTLNVGRVQTPTLKMLVDRDAAITTFKKEKYYHVRLA
                     LSGAEAASERLSDRSEADKLKAACEASKAVCTSLVKEKKTAAPPKLFDLTSLQREANR
                     LFGYTAKQTLDLAQALYEKKLLTYPRTDSAFLTDDMGDTAAGIIKLLCGKFSFMEGAD
                     FTPELAKVLNSKKVSDHHAIIPTMELAKTDIIALPESEKNILTLAGTRLLMATAAPHT
                     FEAVTALFECAGQSFTARGKTVLSDGWKEIDRKYRAALKNKPETDDADSDTEKTLPPF
                     VEGQTFENPAATVTEHDTTPPKPHNEASLLSAMERAGSEDTDPDAERKGLGTPATRAA
                     VIEKLVKGGFVERKGKQLLPTKDGINLVCVLPDTLTSPQLTAEWENNLTQIAKGKADP
                     AAFMEGIEDMARELVKTYPFLSDDKAQMFKPEREALGSCPRCGSPVYEGKKNYYCSNK
                     ECIFTMWKNDRFFEERKVTFTPKIAAALLKSGKVNVKKLYSPKTGKTYDGTIVLADTG
                     GKYVNYRIELPKKK"
     gene            15857..19729
                     /locus_tag="KRH23_002508"
     CDS             15857..19729
                     /locus_tag="KRH23_002508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HHS5225786.1"
                     /translation="MASLRDTVKDYQEELRDGIAWVAFWKTGRSWNAEDFHLELGDYL
                     YPEDRSRMEEIKQADPAAVVVNGYYSGYLGEDMNLDELTAGVRRHYENGYSNIGEFIE
                     AHDDRLPPELTEEARAAAHAAGLPFSEKAYRDGEEPDPYLFDGSMSMEDYELMHRMIE
                     NERSERMAETILSGYLSNLGKYTEGRPAGEWVSFPTTAEHLKEVFDRIGIDGKNYGEL
                     HITEYQSSIAGLTGKLTELESLDELNYLGELLKMQFDDDREKFIAAMAYGDHTRDLQD
                     IINLAQNLDCYWLYPSVQSEEDYGHYLIEELDELELPEEAKNYFLYEEYGRDAAINDG
                     GRFTEQGYIYNNRNTFTQWYDGQDVPEEYRVTPQQQEQADLDAAAVQPALATEQPPVL
                     PIILSSEKPADKMKEITDRLEQGILEIYESERYADYLRTMSKFHDYSLNNTILIALQG
                     GNLVKGYKQWEKEFDRHVKPGEKAIKILAPSPFTVKKQVEKIDPDTQKPVFDKDGKPV
                     TEEKEIKIPAFRVVSVFDVSQTEGKELPSLTYELTGNVEQYQDFFAALEKTSPFAMGF
                     EALSGSIKGRCNYEEKRIIINEGMEELQNIKTAIHEIAHATLHNIDKDTPERPDRRTR
                     EVQAESVAYAVCQHYGLDTSDYSFGYIAGWSSGKELAELKGSLETIRSTAASLIDTID
                     GHFTEIQQAQDKEQTTEQAQPAQETAKQSEAEAAAQELPEETAPIQEKEAQTEPEADT
                     GASNEAPQPPQPEQAAPAAPYYTINEAAAKRAKDMNSFSDYKQGSATAEYRHYVDEAM
                     QLAERQKRRVDPMYHEKIDSLLDTYARKLAANMNKGYEIDARVPSILIAGGSNFPTRK
                     KEKQNAARDSNYREWQDIQGLLDKIRSTGMGGISADDPQAVQKLEKKLESLEKSQETM
                     KSVNAYYRKHKTLDGCPHLPPEELEKLKADMASSWHLEDKPFATWALSNNSAEIRRVK
                     DRIKSLSQQKEIGFVGWEFDGGKVEANTEANRLQIFFEDKPDEATREALKSNGFRWSP
                     KAGVWQRQLTSNAYYAADYVKAIAPLTGEKPTELQRAHIRAQKVAAQEQTTQEQPKQE
                     APQDKDTFSIYQIKGGDETRDLRFEPYDRLTATGHRVDAKNYTLVYSAELTPGTSLED
                     IYTRFNIDHPKDFKGHSLSVSDVVVLHQNGQDTAHYVDSFGYKEVPKFLQPENYLKTA
                     EQTTEQNYNMIDGQINNTPTAAELEEKAKAGGQISLAEYAEALKTDKERGKTAKQEKP
                     SIRAQLKAAKEQTPKKQAKQKTQDLERS"
     gene            19733..20677
                     /locus_tag="KRH23_002509"
     CDS             19733..20677
                     /locus_tag="KRH23_002509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5225787.1"
                     /translation="MKLQKFENVDVIASLEAIMKQHTAFYQSDFEIDKQILQKAAGSP
                     IPEDRRLLWFSRPSGTCCFRERDVFLKDTRQHNTWRFYGEQTRDTILAYAVELTGTEQ
                     GKIKGNLYELDYLQHFREVIEKSIPADNYTLIYEHGELTKPAGQYFDGDTDPQLGKFI
                     RFEAQPNDPEALKILLGEQKKNRTPHTQGDFQLHIAALHDRRIETEARRIVENVKGLG
                     ETDSPEKTHCAVELSPYFVPLATDKDMERLFSMLPYKSLSFSTLEGRHGVYALIDKSE
                     RNKEMRKSRPSVRAQLQTEKSPKIPKKTAKSKHHEMEV"
     gene            20680..20886
                     /locus_tag="KRH23_002510"
     CDS             20680..20886
                     /locus_tag="KRH23_002510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposon-transfer assisting family protein"
                     /protein_id="HHS5225788.1"
                     /translation="MIRLTVEEMNLLSIYHEGSKAQLMENMTAALPFMDKDMRELAKR
                     TLAKIAPLTENEYAELAIFAADEV"
     gene            20883..21248
                     /locus_tag="KRH23_002511"
     CDS             20883..21248
                     /locus_tag="KRH23_002511"
                     /inference="COORDINATES: protein motif:HMM:NF025557.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich VLP domain-containing protein"
                     /protein_id="HHS5225789.1"
                     /translation="MTGGKRLTPPQSRKVNSLVKKECCNCERGHCILLDDGEECVCPQ
                     LISYSLLCKWFQIAVLPLDKLLYAELFKTEDKKRCTECGTFFVSKSNSVKYCPDCRKR
                     ITRRQAAERMRKRRAAVTQ"
     gene            complement(21420..21887)
                     /locus_tag="KRH23_002512"
     CDS             complement(21420..21887)
                     /locus_tag="KRH23_002512"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5225790.1"
                     /translation="MKGFDKDMTKETPANIGQLVKDANNKSSWKIRLAALNELKQYDC
                     QQSKDVITRLALHDKVYKVKEEAFRAAQAMGITYRGNPIRLGRKDIGFKTKDFTKVFL
                     RIKREKSMEELDLYVFKEAFKTIAAEMYDVMEFEKGQKFDDWIANTYKCLPKK"
     gene            complement(21958..23301)
                     /locus_tag="KRH23_002513"
     CDS             complement(21958..23301)
                     /locus_tag="KRH23_002513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HHS5225791.1"
                     /translation="MAVTKIKPIKSTLSKALDYIQNPDKTDGKMLVSSFGCSYETADI
                     EFGFTLAQAIEKGNNLAHHLIQSFEPGEVDYEKAHEIGKQLADAVTKGQHEYVLTTHI
                     DKGHIHNHIIFCAVNFVDYHKYNSNKRSYYGIRNMSDKLCRENGLSVVVPGKGSKGKS
                     YAEYQAEKAGTSWKGKLKIAVDTLIPQVASFEELLQRLQAAGYEIKSGKYISCRTPGQ
                     ERFTRLKTLGTDYTEEAIRERIEGKRTKAAKAPKEQRGVSLLIDIENSIKAQESRGYE
                     QWAKIHNLKLAAKTMNFLTEHKIEQYADLVSRIEEINAENEKTADALKSVGKRLADMA
                     VLMKHVATYQKTKPVYEAYRKAKDKDAYRAKQESSLILHEAAVKTLKAAGVTKLPNLA
                     AMQEEYGKLQVQKEALYANYGKLKKQVKEYDIIKQNIDSILRLEKEPERRKEREY"
     gene            complement(23262..23591)
                     /locus_tag="KRH23_002514"
     CDS             complement(23262..23591)
                     /locus_tag="KRH23_002514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002610348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization protein"
                     /protein_id="HHS5225792.1"
                     /translation="MNGRKRKVQIKFYVTEEERALIEQKMKLVPTRNMAAYLRKIAID
                     GYIIQTDHSDIKAMTAEIQKIGVNINQIAKRVNATGSVYQEDIEEIKGVLAEIWRLQR
                     LSLLKAR"
     gene            complement(23835..24194)
                     /locus_tag="KRH23_002515"
     CDS             complement(23835..24194)
                     /locus_tag="KRH23_002515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005933802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHS5225793.1"
                     /translation="MKQSKEKFDFKAFGQAIKAARKAKGISRNQLADTLNIAPRYIAS
                     IENSGQHPSLQILYELVTLLDVSVDQFFFPEREQEKSTRRRQLDTMLDTMSETDLKIM
                     SATAKGIEEANNDRTGE"
     gene            24505..24768
                     /locus_tag="KRH23_002516"
     CDS             24505..24768
                     /locus_tag="KRH23_002516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CD3324 family protein"
                     /protein_id="HHS5225794.1"
                     /translation="MKYKNAQLILPDALVKELQSYVQGEYIYVPVEQEQQKRWGEVSG
                     YRKELEQRNQKIKQEYQSGISINCLAEKYCLSLYAVRKIIYQK"
     gene            24905..25612
                     /locus_tag="KRH23_002517"
     CDS             24905..25612
                     /locus_tag="KRH23_002517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HHS5225795.1"
                     /translation="MCTRFVYNGNDMITGFNFDIDLAVWKHKVIKEKERFYIGILRPD
                     GTYHSYHGINRNGNVGTLLYVHGNPAGIYRDNSDCITIADLTEQFIKAQISFDEVLQI
                     VKSKQITYAPDATMQAMLSDSHGHVLIIEPGIGYKEEYEQYSLITNYSLMKPESTKCF
                     IVPGDDRYERALKKIEKYGPDFSISDAIHLLYDVRQEGAWATRVSFVYSAKEQTVYYV
                     ENNHFECIQTFTFPLER"
     gene            25626..26246
                     /locus_tag="KRH23_002518"
     CDS             25626..26246
                     /locus_tag="KRH23_002518"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0046677 - response to antibiotic [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CatB-related O-acetyltransferase"
                     /protein_id="HHS5225796.1"
                     /translation="MLQKIYPRSKDKETVYLKSVITNPNIIVGDYTMYNDFVKEPKDF
                     EKNNVLYQYPINQDKLIIGKFCSIACGAKFIFNSANHTLSSLSTYPFPIFFEEWGLDV
                     KDITKAWDNKGDIVVGNDVWIGYEAVILAGVTIGDGAIIGARAVVTKDVPPYTIVGGV
                     PAKQIRKRFNEETIDTLLKLKWWDWSKERISKNIAAIQSGNLGYLL"
     gene            26330..26854
                     /locus_tag="KRH23_002519"
     CDS             26330..26854
                     /locus_tag="KRH23_002519"
                     /inference="COORDINATES: protein motif:HMM:NF015513.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HHS5225797.1"
                     /translation="MSSIDLVVLGIVLEKPQSAYDIQKDVEYHNLSKWTKISVPSIYR
                     KVLQLKEKGYLESDIVKGDKFADKAIYSITEKGKEYFEKLMFTYASQDVPLLFDFNVV
                     IANLNKVSSNEAIKLIAQLRESIKISAKANEDYAIQYATIPLVGRTIFEQQKLLYNSL
                     LEWLNNFEAQMSKE"
     gene            26859..27275
                     /locus_tag="KRH23_002520"
     CDS             26859..27275
                     /locus_tag="KRH23_002520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006439529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjdF family protein"
                     /protein_id="HHS5225798.1"
                     /translation="MSVKSSLTVMFEAPFWIGVYERFDEGYYEVCKITFGSEPKDYEV
                     YDFLLKNWNSLKFSPPIKSEITEERKINPKRMQREINNQLQNKGMGTKAQQALKLQHE
                     QNKMERKVKSKEQREAEKERQYALRQEKRKAKHRGK"
     gene            27278..27466
                     /locus_tag="KRH23_002521"
     CDS             27278..27466
                     /locus_tag="KRH23_002521"
                     /inference="COORDINATES: protein motif:HMM:NF025568.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HHS5225799.1"
                     /translation="MNSENWIYCPVCKNKTRLQIREDTELKNFPLYCPKCKQETLINV
                     YKLNISVIKEPDAQTQSR"
     gene            27617..28060
                     /locus_tag="KRH23_002522"
     CDS             27617..28060
                     /locus_tag="KRH23_002522"
                     /inference="COORDINATES: protein motif:HMM:NF018184.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HHS5225800.1"
                     /translation="MKIEEFKNITIAYIRRTGNYGFENKIFMENFKEYLREKELLDKS
                     SVILGIALDNPAMTDKNKLRYDVGLIVNGNPDIALDIRKIPDGIYAVFELPHTEQDIT
                     AFWSNIQKLVGSLSVDETKPVIERYPADKVAKHLCEFCIPLKKLS"
     gene            28479..29000
                     /locus_tag="KRH23_002523"
     CDS             28479..29000
                     /locus_tag="KRH23_002523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HHS5225801.1"
                     /translation="MAKQKVACIIPRKGEVLPPFGRKEVNTMTPNRREFEKQCTFQKF
                     CKSVLHNEACNAHEEIRRRRVREVTFSDLALYEERQLYTVDKYFQDEEAEPSYQMAGK
                     EITPKLLLEAIRALPEERRKIVLLYYFEGLTDIEIGKQLNISRSTVQYRRTSSFEQLK
                     KYLEENADEWIEW"
     gene            28981..29238
                     /locus_tag="KRH23_002524"
     CDS             28981..29238
                     /locus_tag="KRH23_002524"
                     /inference="COORDINATES: protein motif:HMM:NF024059.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHS5225802.1"
                     /translation="MNGLNGKPTEYPENALVPYPVILAASKGDPNAMKIVLQHFSGYI
                     ASLSMRKLYDERGNVYFGVDEEIRERLQAKLMRAILTFRAE"
     gene            29677..29841
                     /locus_tag="KRH23_002525"
     CDS             29677..29841
                     /locus_tag="KRH23_002525"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5225803.1"
                     /translation="MEDKVSYMIDKDEINQQKMQLVVINRRPQYLQKPQEVAKREIAR
                     QLFQIFRKYE"
     gene            29925..31433
                     /locus_tag="KRH23_002526"
     CDS             29925..31433
                     /locus_tag="KRH23_002526"
                     /inference="COORDINATES: protein motif:HMM:NF012464.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HHS5225804.1"
                     /translation="MMYDALYGRQSIEKKDSISVESQLEYCRYETHGDPYIEYADRGF
                     SGKNTNRPDFEKMMNDIRAGKIKRVIVYKLDRISRSILDFANMMEVFQEYHVEFVSST
                     EKFDTSTPIGRAMLNICIVFAQLERETIQKRVTDAYYARNKRGFYMGGRIPYGYRLKE
                     TIIDNIRTSMYEEVPEESEQLKLIYSLYADPANSLGDIIRYLNKHGIKQLRGGNWTSA
                     RISEMLRNPVYVEADIDVYNFFKSQGADVYNPASDFTGYNACYLYKGTVSTTRKQCDL
                     TDKEIVLAPHKGFISSATWLACRIRCLNNRQSTQTCKPKNSWLTGKVKCGNCGYALVI
                     RKAKTKWGRYFVCSQSGHSGNCKGTGSTVYADVLEEYMLKAIREKLSEFKKLSDEEEN
                     KSVPKVSKNKIRLTQIDEEINDLLSKVGSANAILMKYINDKVSELDTERQTLQEEIIS
                     LTCTHTENKMGQITDHVKKWDNISFEDKQAVVDALIKVIKVANGNIEITWKI"
     gene            complement(32211..32399)
                     /locus_tag="KRH23_002527"
     CDS             complement(32211..32399)
                     /locus_tag="KRH23_002527"
                     /inference="COORDINATES: protein motif:HMM:NF024242.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHS5225805.1"
                     /translation="MPYKYFTEFCLLKATQFLKGTNELISDIAIKVVFHQIIYFSKCF
                     KEKTGYSPKVYRNIKKEI"
     gene            complement(32499..32849)
                     /locus_tag="KRH23_002528"
     CDS             complement(32499..32849)
                     /locus_tag="KRH23_002528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5225806.1"
                     /translation="MGKVRIGCKKEKYFYVRNPVKSLVDRITENEQFAIYHFTHKYNW
                     RNKVFSILQRLIRLEKSKNELYMYEALVSVSFLWLIMIKNIVLPPIKHKNIINIHMQK
                     ILRYIEKYYCFTLY"
     gene            33166..33699
                     /locus_tag="KRH23_002529"
     CDS             33166..33699
                     /locus_tag="KRH23_002529"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003908 -
                     methylated-DNA-[protein]-cysteine S-methyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HHS5225807.1"
                     /translation="MQYISYYHSPIGNILLASDNIGLTGLWFENQKYYAYNLDQEHQE
                     KELPIFEQTKKWLDIYFSGKEPNFTPSLHMVGTPFQTTVWKILQQIPYGKTITYGEIA
                     YKVAQQKGISKMSAQAIGGAVGHNGISIIIPCHRVVGTNGSLTGYAGGIDRKIKLLSL
                     EKVSVQHYFIPKKGSAL"
     gene            33901..34104
                     /locus_tag="KRH23_002530"
     CDS             33901..34104
                     /locus_tag="KRH23_002530"
                     /EC_number="2.1.-.-"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: protein motif:HMM:NF019846.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HHS5225808.1"
                     /translation="MCLDAVIYMLQTGKQGADKKYLDNMFFVKGYVEELLFLDNSYDI
                     VFSCIVFHHCTNVQNIFCIFWKW"
     gene            complement(34712..35350)
                     /locus_tag="KRH23_002531"
     CDS             complement(34712..35350)
                     /locus_tag="KRH23_002531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid stabilization protein"
                     /protein_id="HHS5225809.1"
                     /translation="MDEKILELLQEIQGNISNMQGSISGIEGTISDMQSNINGIEGTI
                     SDMQSNINGIEGTINSMQGNINGIENTISGMQGTIGDMQGSISGMNGTISDMQGSISS
                     MDGTINSMQDSITDMQVEIKEVNSRLDNMEPDIKDLKTGQVETSSKLDTIQSDVTEIK
                     SDVKINRNTLDTVIKHTSSLVKDTSDIKNDLNNIEIVTSKNSNDIAKLKSVK"
     gene            35816..36229
                     /locus_tag="KRH23_002532"
     CDS             35816..36229
                     /locus_tag="KRH23_002532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003507530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3795 domain-containing protein"
                     /protein_id="HHS5225810.1"
                     /translation="MKMPKESIDTIMFAPCGMNCMVCYKHCYHKKPCAGCLNGDTGKP
                     EHCRKCKIKDCVCQKGLFYCFECFNFPCKLIKNLEKSYNKRYQASLMENSKFVQQYGL
                     EKFMQKQKERYTCSKCGGIISIHDRECSECQEKVK"
     gene            36302..36838
                     /locus_tag="KRH23_002533"
     CDS             36302..36838
                     /locus_tag="KRH23_002533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GrpB family protein"
                     /protein_id="HHS5225811.1"
                     /translation="MIGLKCGMVKLLEHQMIWDKSAKDVIILLKSIWDKTAIDIQHIG
                     STSIPSISAKPIIDIVVGVASLEETKLYLERLEQCGIVFRGQDVPKQLLFAMGDFEKN
                     TRTHHIHVVEWNSVAWNNYINFRDYLNTFTDKAKLYDSHKQKLALQFEDNRKIYTQRK
                     QELINILLEEARLWRINT"
     gene            37052..37663
                     /locus_tag="KRH23_002534"
     CDS             37052..37663
                     /locus_tag="KRH23_002534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005247 - voltage-gated chloride channel
                     activity [Evidence IEA];
                     GO_process: GO:0006821 - chloride transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HHS5225812.1"
                     /translation="MIGEGLMVGAVAGLIVLLYRILLGQAGTWLSQILKFVEGSTIKI
                     IAWFAVLAVLAWIVSKLVDWEPMISGSGIPQLEGEMTGKIKQVWWRVLPTKFIGGFLS
                     LMGGLALGREGPSIQLGAMAGKGISRALDRGKTEEKFLLTCGASAGLSAAFHAPLAGV
                     MFSLEEVHKNFSVSVLISVMTASLTADYISANFLGMESVFQFD"
BASE COUNT        11801 a         7730 c         8460 g         9807 t
ORIGIN      
        1 accagttata atatagaacc agtatacaat ttttaaaaat aatgctattt taaaattcta
       61 aaaattaagg aggataatta atgggatatt taaaagagga taaacaagac tattgttgtg
      121 aatttgctag accatacatc aatcgtcaaa tttatgatga cacatacaat ccaaaaacag
      181 cattaaaaag aggtacttta tttcctgaat tagatttaat agagtcaaat aactataatg
      241 attggctata tgcaaatcct aaaaatagag ttagagctaa aaaagggggt aacatgtact
      301 aatgtcatta aatagaagag aacttttaga gagaatttca gaatatcaat ttgcctgtat
      361 agaattaaat ttatatttag ataacaatcc aagggataag aaagctcttg attcatacaa
      421 cagatactgc gataaattta cacaagctgt gtgtgattat gaatctaaat atggagcatt
      481 aactaatttt ggatatgaat caagtgaata tccttggtca tggatatctg aaccttggcc
      541 atgggacaaa tcattttata aataaaatta ttaaacttta aaattagatt tattattaaa
      601 tatatattaa ggaggagtaa gataatatgt ggatttatca aaaaacactg gaacatccag
      661 ttaacataag acaagcagac cctagaatgg caaaatatat catgactcag ttgggaggac
      721 ctaatggtga gttggcagct gcaactagat atcttcaaca aagatatact atgccaactg
      781 gaaaatctcg tgcactttta actgatatag gtacagagga aatggctcat gttgagataa
      841 tttcttcagt gttatatcaa ttaataggca attgtactcc agaagaactt aaggctgctg
      901 gacttggtag taattatgct aattttggac atggtcttca gccagtagat tctaatggag
      961 taaactttac tacaagttat attaatgtct ttggcgattc ggtaactgat ttacatgagg
     1021 atatggctgc tgaacaaaaa gcattggcta cgtactatca attaataaat ttaactgatg
     1081 accctgattt gaaagatata ttgagatttt tgggtgagag ggaagtagtt cactatcaaa
     1141 gatttggtga agcaaagcgg gaagattgta gtaaaaaatc aacggtgctg aaagcccaca
     1201 aatacagcac ttttggaaag atactatcaa tcagaaaaac gcaggacgta ggcataagcc
     1261 gccctatctg ctgctaaacc tcaaaattga taagaacaaa aaagagatag gacaagctgc
     1321 ttctacttat aatttaatat tgacccgcat atagcggcgt ttctcactcc tacacaggag
     1381 aacaggaacg ccgctatttt tatgccctca tgttacgcag taaggggcaa aaaagccttg
     1441 atttatgcgg ctcttagagc gtggaaatga gaaagacaag ggttgatacc ttttccctca
     1501 aaaccgcgtt tctactgcgt aacaaattca accaaaggag tgatgaagct atggcagttt
     1561 tccgagtgga aaagaacaaa ggttatacgg ttatgagcaa ccaccattta cgcaacaagg
     1621 aactttccct aaaggcaaag ggcttgttat cgcaaatgct ctcacttccc gaagattggg
     1681 actacactct tgcagggctg tcccttatca accgggaaag tatcgacgct atccgcaccg
     1741 ctgtatggga gcttgaaaaa gccggatata tcacaaggcg gcagggacgc gacgagaaag
     1801 gcaaaatgac cgctatcgag tacaccattt acgaacagcc acagcccccg gcattggatt
     1861 gtccggtatt ggaaaatcca acagcggata acccgatatt ggaaaatccg acaccggata
     1921 acccgacgtc ggaaaatcca acgcaattaa ataaagaact attaaagact aacttaccaa
     1981 aaaaagaaaa attaaataca gatatatcaa gtacccattc cattcctttc cattccctaa
     2041 acccctctcc cttagaggac gcggcacagc cgccggaacg gaagcgaacg gaagcgacag
     2101 acgcataccg agtgtatgag gaaatcatca aggacaatat cgagtacgac tatctgatac
     2161 aggacagata ccttgaccgg gacaggatag aggaaatcat tgcccttatc cttgaaaccg
     2221 tctgcaccaa acgaaggaca atccgtatcg caggggacga ccacccggca gagcttgtaa
     2281 aagcaaagtt tatgaagctg aatggcgagc atatccgctt tgtgcttgac tgtatgcagg
     2341 aaaacaccac caaaatccgc aacatcaagc agtacatgaa agctgccctt ttcaatgccc
     2401 cgtctacgat tggcagctat tacacgtccc ttgtatctca cgatatgtac ggcgggcgca
     2461 ctatccagtc ggcaagaagc aagggcatac ccgactacac ctgcaacgag ggcgaaagcc
     2521 tgtaaaccaa cccaaaggag gattttatga tgacacagaa aacaggagct ttgatttttg
     2581 atgaaaccgc tgaccgctac gacattcgct ttgacgtaaa cgactactac gggggcttac
     2641 attgcggcga ctgcatggag gtttttgtgc ggggaaaatg gaagccgacc cgcatggagt
     2701 acggggacaa ctggtatctt gtgggtattc gggcggcaga cctttccggg ctgcgggtgc
     2761 ggatttaaca gggcggcgtg aaaacggacg ctcttttttc atgcccgctc cattttccgg
     2821 cggcgggcat accaccatag aacacgaaag gaggaacccc attgcaagag gaaaccaacg
     2881 aaaagaccat agccctttac atcaagaccg ggaagctgac cgcacagcag ctccaaaagg
     2941 ctatgaaagc cctgcttgca cagatgaaaa agcagcatga gaaacagaaa atcccgcatg
     3001 gcaaacagac cctaaagcag cttatgaagc agaacgcagg cgtttccaac attgaaatca
     3061 caaaggacaa tatcaaagcc tttgagagta cggcgaagaa atacgggatt gactttgccc
     3121 taaaaaaaga cagcaccgaa accccgcccc gctatcttgt gtttttcaag ggacgggacg
     3181 cggacgcact gaccgcagct ttcaaggagt tttccgcaaa gaagctgaca caggaacaaa
     3241 agccctctat ccgcaagctg ctttccactc tgaaagataa ggcggcagct ctgaacgcac
     3301 agagggaaaa agtgaagaaa aaggacaggg aggtatcgct atgaagccgg aacttaaaaa
     3361 gctgcttatc ctaaatgccc cctatctgct ctttatctat ctctttgaca aaatcggaca
     3421 ggcggtgcgg ctctctccgg gggctgacct gtccggcaag gttctgtcgc ttagggaggg
     3481 cttttctatg gcttttgcta atccgcttcc cagtcttgcc cctatggatt tactgatagg
     3541 gattttcggc gcggtgctta tccggctgat tgtctatgtc aaaggcaaga acgcgaagaa
     3601 ataccgcaaa ggtgtggaat acggctctgc ccgttgggga actgccgaag atataaagcc
     3661 ctacaccgac ccagtatttc aaaataacgt gctgctgaca cagacggaac ggcttaccat
     3721 gaacagccgc ccgaagcagc cgaagtatgc aaggaataaa aatatccttg ttatcggggg
     3781 aagcggcagc ggcaagacga gatttttcgt aaagcccaac cttatgcaaa tgcactcaag
     3841 ctacgttgta accgacccaa aaggaacggt tttagtcgag tgcgggaagc tcttacagcg
     3901 gggcggctac ctgataaagg tactgaacac gattaacttc aaaaaaagca tgaaatacaa
     3961 tccctttgcc tatctccgca gcgaaaaaga cattttgaaa ctggtaaata ccttgattgc
     4021 caacaccaaa ggggacgggg aaaaatccgg ggaggatttt tgggtaaaat cggaacggct
     4081 cttttactgc gcccttatcg gctacatttg gtacgaagcc ccggaggaag aaaagaactt
     4141 cacaacgctg cttgaaatga taaatgccag tgaagcccgc gaggacgacc cggaatttca
     4201 gtcccccgtt gacctcatgt ttgaacggtt ggaggaaaaa gacccggaac actttgctgt
     4261 ccggcagtat aagaaattcc tgttatctgc gggaaaaaca agaagctcta tcctcatttc
     4321 ctgcggtgcg cggcttgccc cttttgacat taaggagctg cgcgacctta tggaaaccga
     4381 cgaaatggaa cttgacacca taggcgaccg caagaccgcc ctgtttgtca ttatcagcga
     4441 caccgacgac acttttaact ttgttgtgag tattctttac acacagctct ttaatctcct
     4501 ttgcgacaag gcagatgatg aatacggcgg caggctgccc gtccatgtgc gctgtctgtt
     4561 agacgagttt gcaaatatcg ggcagatacc gaagtttgaa aagctcatag ccactatccg
     4621 aagccgggaa atctccgcgt cgattatctt acagtcgcaa agccagttaa aggcaatcta
     4681 taaggacaac gccgatacca tagccggcaa ctgcgacacc acccttttct taggcggaaa
     4741 ggagaaaacc accctcaaag aaatgtcgga aatcttgggg aaagaaacca ttgacagctt
     4801 caacacttcc gagaaccggg ggcgggaggt atcgcatggg ctgaactatc agaagttagg
     4861 caagcagctt atgacggaag atgaaattgc ggttatggac ggcgggaaat gtatcttaca
     4921 gctacgcggg gtgcgcccgt tcttctctga taagtacgac attacaaagc accccaacta
     4981 taaatatctt tccgactatg acaagaaaaa tacctttgat atggaaaagc atttaaggcg
     5041 cagacccgcc cttgtgaagc cggacgaagt atttgactac tacgaaatca gcgaaagcga
     5101 tttgcaggag gacaccgacc atgaataaac gtatcagaaa gaaaaaggac aagaaaatca
     5161 cagaagccat aaacgggctt gttttcattg ccgagcgacg ggaacagcaa cggcaggcag
     5221 ctatccggca gtttgtgaaa cggtgtgaag ccctgtatga gcagcaacga aaggagggat
     5281 tgacgcagta acaaagaaac agacaactta cagaatacgc gcccctactg gaaaatccat
     5341 aacgcccaca ctcaaaactg aataccgccg cgcggcagac acataggcag cgcggggaac
     5401 ccgccacaat ccggcgggct tatgaccgcg gcagttacaa aactgaccgc cgttttttat
     5461 gcccttttac ggggcaagcc gcatttgcgg cagaaaggag ctttatggaa ttttttaact
     5521 ctgctatcga cgtattacag acccttgtta tcgcactggg cgcaggctta ggcatttggg
     5581 gcgttatcaa tctcttggag ggatatggaa acgacaatcc gggtgcaaaa agtcaaggca
     5641 ttaagcagct tatggcgggc ggcggtgttg cccttatcgg cactatcctt gtacctctgc
     5701 tttccggtct gttcggataa gtttacggag ggtagcctat ggagagcata cttgacgcga
     5761 ttaacgaatg gataaaggaa atccttatcg gcgcgataaa cggtaatctg tcaactatgt
     5821 tcggggacgt aaacgaaaaa gtaggcacca ttgcagcgga ggtaggcaag accccgcagg
     5881 ggtggaacgc gaacattttc aacatgatac aaaatctgtc tgaaaatgtg attgtaccca
     5941 ttgcggggct tgtcattacc tatgtcctct gttatgagct tatcagcatg gtaacggaaa
     6001 aaaacaatat gcacgacgtt gacacattca tgttctttaa gtggtttttc aaagcctttg
     6061 ttgccgtttt cttggtaacg catacctttg atataacaat ggcagtcttt gatatggcgc
     6121 agcatattgt gtccggcgcg gcgggggtaa tcggcggcga tacgaatatc gacgtaaccg
     6181 aagcccttgc cgccatgcag gagggactaa acgatatgga aatccccgaa ctactgttac
     6241 ttgtcatgga aacgagcctt gtaagccttt gtatgaaaat catgtccgta ctgataaccg
     6301 ttatcctcta cggcagaatg attgagatat acgcctactg ttccgtttcc cctatcccct
     6361 ttgccactat gacaaaccgg gaatggggac agattgggaa caactaccta aaggggctgt
     6421 ttgcactggg ctttcaaggc ttcctcatta tgatatgcgt cggcatttac gcagttttag
     6481 taggcgaaat ggtcttagcg gacaatctgc acagcgcgat tttttccctt gcagcctata
     6541 ccgttatcct ctgtttctcc ctgttcaaat ccggcgcact ggcaaaatcc attttcaatg
     6601 cacattaaca cagcacacgc gggaaagtcc cgcagaaagg aggtcttttc ttggcgtatg
     6661 tacctgtacc caaagactta tccaaagtca aaacaaaagt cgctttcaat ctgacaaagc
     6721 ggcaaatcct ttgtttttca gtggcacttc ttatgggact gccgcttttc tttttgctta
     6781 aagacagcgc agggacgagc cttgcggcaa tggcaatgat tgtcgtcatg cttccctgct
     6841 tcttggttgc catgtatgaa aagcatggac agccccttga agtggtcata aagaacatca
     6901 ttcagacaaa atttacccgc cccaaagtgc gaccgtatca gacggaaaac ctatatgcac
     6961 tcttggagaa acagcgggca ttagaaaagg aggtatcagc gattgtcaaa aggacagaca
     7021 aaaaagacgc gggaagccgc aggaaacagg cgtaagctga cccgcgcgga aaagaaacag
     7081 atagcggcgg ttatccggca ggcaaagggg gacggcaaag cccacaccgc acagcagacc
     7141 attccctacc ttgccatgta cccggacggt atctgcaaag tggcacagcg gaaatattca
     7201 aagagcattg tttttgagga tattaactat cagcttgcac agacagacga taagaccgcc
     7261 atttttgaaa actggtgcga tttcctcaac tactttgacg caagcgtgaa cgtgcagctt
     7321 tctttcatca atcaaggctc acagcaggaa caggcagcgc gggcaatcca tatcccgccg
     7381 caaaatgacg attttaattc tatccgcacc gagtattccg atatgctgaa atcgcagctt
     7441 gccaaaggga acaacgggct tgtaaagcac aagtacatca cattttccat tgaagcggac
     7501 aatccggcgg cagcaagggc gcgtctttcc cgtattgaaa ccgacgtact caacaatttc
     7561 aaggtgcttg gggtatcggc gcacccctta tccggctatg aacgtctgaa agtgctgcat
     7621 ggggtattcc acccggcagg cgagcctttt tcattctctt atgactggct gaccccgacg
     7681 gggcttacca caaaggactt tatcgccccg tcctctttca agtttgggga gggacgctac
     7741 tttgctatgg ggaaaaaggc gggggcggta tcgttccttg aaatccttgc cccggagtta
     7801 aacgaccgta tcttagcgga tatgttggac ttggaaacag gggttattgt caatctccac
     7861 attaaaagta tcgaccagtc ggaagcaatc aagaccatta agcgcaaaat cactgacctt
     7921 gacaagatga agattgagga acagaaaaaa gcggttagaa gcggttacga tattgacata
     7981 ctcccgtccg accttgccac ctttgggaat gaagcaaaga atttattgca ggatttacag
     8041 agccgcaacg agcgaatgtt tctccttacg ttccttgtgg taaacatggc agacacgaag
     8101 cggaaactgg aaaatgacat tttcgcagcg gcgggcattg cacagaaata caactgcgcc
     8161 ttgacccgtc ttgactatca acaggaagcg gggctgatgt cctctatccc tttgggggag
     8221 aaccttatcc cgatacaacg gggacttacc acatcaagca ccgctatttt tatcccgttc
     8281 atcacgcagg agctatttca gactggggct gccctgtatt atgggctgaa cgctttaagc
     8341 aataacatga tactctgcga ccgcaagcag cttaaaaatc caaacgggct tatcttggga
     8401 acaccgggca gcggaaaatc ctttgcagca aagcgggaaa tcacaaacgc ctttctcatt
     8461 accgacgacg atatttttat ctgcgacccg gaagcggaat attttgccct tgtaaaacgg
     8521 cttggcggac aagtgatacg cttatccccg accgggaaag gcatggacgg tacgccccag
     8581 tatgtgaacc ctatggatat gaaccttaat tacagcgagg acgacagccc ccttgcactg
     8641 aaaagcgatt ttatcctttc cctctgcgag cttgtcattg gcgggaaaga gggcttgcag
     8701 cccgtagata agacggttat tgaccgcgcc gtaaggaatg tgtacaggga ctatcttgct
     8761 gaccctgtac cggagaaaat gcctatcttg ggcgaccttt acgacgagct gttgaagcag
     8821 ccggagccgg aagctgcccg cattgcggcg gcattggagc tgtatgtttc cggcagcctt
     8881 aacgtattca accataaaac gaatgtggag ctttctaacc gccttgtctg ctttgatatt
     8941 aagcagcttg gaaagcagct caaaaagtta ggtatgctca ttgtgcaaga ccagatatgg
     9001 aaccgcgtta ccattaaccg ggcagaaaag aaatctaccc gctactatat ggacgaattt
     9061 catctgcttc tcaaagagga acagaccgcc gcttacagtg tggagatttg gaagcgtttc
     9121 cgtaaatggg gcggcatacc cacagctatc acgcagaaca taaaggactt gcttgcttcc
     9181 cgcgaggtgg aaaatatctt tgaaaactct gattttgtcc tcatgctcaa tcaggcgcag
     9241 ggcgaccggg ctatccttgc aaagcagtta aatatcagcc cacagcagat gaagtatgta
     9301 acccacaccg aagcaggcga gggacttatc ttctatggaa atgtggtgct tccctttgta
     9361 gaccatttcc cgaaagacac cgagctttac cgcattatga cgacgaagcc ggaggaagtg
     9421 agcagcctat gaaaacagac gtaattatca accgggacgc gctttgtgct ttacaggagt
     9481 taccctctga aagtgtccat tgctgcgtta caagcccgcc ctactatgct ctgcgggact
     9541 atgggcttga cgcacaaatc ggacaggagg acacgccgga gcagtatatt gacaggctga
     9601 ccgctgtttt tggcgagctt taccgggtac tgagaaaaga cggtacgcta tggctgaata
     9661 ttgcagacac ctattgcggt actgggaata aaggcggcta tgctgacccg aaaaacccaa
     9721 aggggcgcat cggacagcgg attgcaagga acagccgcgt taccggctgc aagcaaaagg
     9781 acttaatcgg tattccctgg ctcctggcgt tttccctgcg tgaacagggg tggtatctgc
     9841 gcagcgatat tatctggcag aaacaaaacc ctatgccgga aagctgcaaa gaccgcccga
     9901 cccgctgtta tgaacatatt ttcctgctct caaaagaaaa gaaatactac tatgacgctg
     9961 ccgccattgc agaaccctta gcacctacta ccgcagaacg gtatcgcaga gcgcgcagca
    10021 ccaacagcaa atacacacat gaaatccccg gacaaggaaa ggtacagggg ctaaaccaac
    10081 cgcgggacgg tggctactat gacgacgcgc tcatgccgac tacgaggaat aagcgggacg
    10141 tgtggctgat taacaccgtt ccctataaag gggcgcattt tgcagctttt cccccgaaat
    10201 tagcagaaac ctgtattttg gcaggctgcc ccaaaggtgg gattgtctta gacccgtttt
    10261 ttggaagcgg cacgaccggg cttgcggcaa aaagccttga ccgtcattat atcgggattg
    10321 aattaaatgc agaatattgc gcccttgcga gggcgcggat tggaggtgca ggactatcaa
    10381 acagctaaaa ccacgcgata aaattacaca gaaaatgacc cgcgacggtg cggtggaagt
    10441 caacgaaaca cagcagaccg ccgagcgtat cagcagcagg gaagcagaca gcgacttttc
    10501 acagccggac accgctaccg cagagcgcgt catggaacac cttgacgcag cccatacccc
    10561 aaaggcaaat aaaaaggcag tcaaaaaaga gcaggaagct actgttttgc gtacttccac
    10621 ttcccgctta aagtttaccg atgaggaacg gacaacgccg gaactggaac cgtatatcaa
    10681 aaaatcagaa aaagcagccg acaaactgga cgcagcaaag gcagctatcc cgaagcagaa
    10741 aaaactggta aaagagcgca cctttgagga agccaccgga aaggcaaaga cccgcctgca
    10801 ctttgaggaa caggaaaagc ccatacccgg cggcaaaccc cacaataacc cgttatcccg
    10861 ccccgcgcag gaagcgggta tttttgttca caataaaatc cacagcgtcg agaaagacaa
    10921 ttccggtgta gagggcgcgc ataaatcgga ggaacttgcc gagcgcggcg caaggtacgg
    10981 gacaagaaaa ttaaaacagg gctaccgcag ccataagctg aaaccctacc gggaagcggc
    11041 aaaagcagaa aaggcagcat ttaaggcaaa cgtcaacttc cagtatcaca agaccctgca
    11101 cgacaaccca cagcttactt ctaacccgct ttcccgtttc atgcagaaac agcagataaa
    11161 acgccagtat gcaaaggcgg caaagaaagg agggacaaaa gccgcagcgg aagctacaag
    11221 aaagacggcg aagaaaactg ccgaggaaac aaggaaagcc gccgcatttg cggcaagaca
    11281 cccggcgggc attttgattg cagttgccgc gctgcttctc tttattatga tttccgcagg
    11341 gctgtcctct tgcggggcta tgttttcggg cttgacaaac ggcgtgcttg gcacgtccta
    11401 tacgtcggag gacagcgacc ttgtggcaac ggaacagagc tatgctgcaa tggaaaacga
    11461 gctgcaaagt gagattgacg ctatcgaaag tactcacagt ggctatgatg aataccgcta
    11521 tgaccttgac actatcgggc ataaccccca cgaattagcg tcgtacttga ctgccctttt
    11581 acagagttac accccacaaa acgcacaggc agagctaaag cggctgttcg gcttacagta
    11641 caccttgacg ctgacggaag aaatcgagat acgcaccacc actgacgagg agggcaacga
    11701 ggaagaatac gaataccgta tcttaaatgt gaagctgaca aacaagccga ttgcttccct
    11761 tgcggaagaa ctgctgaacc cacagcagtt tgaaatgttc aaagtgtact tacagacaca
    11821 gggcaacaaa ccattgattt ttggcggcgg ctctcccgac ggaagcccgt ccgaggattt
    11881 aagtggcgtg gagtttgtaa acggtacgcg caccggaaat caagagctta tggagcttgc
    11941 aaagcagcaa gtcggaaatg tgggcggcta cccttactgg tcttggtacg gctttaacag
    12001 ccgcgtggaa tggtgcgcct gttttgtatc atggtgctac aatcaagccg gaaaaagcga
    12061 accgcgcttt gcgggctgcg aatggcaggg tgtcccttgg tttcagtcaa ggggacaatg
    12121 gggcgcacgc ggctatgaga atatcgcacc gggcgacgct atcttttttg attgggattt
    12181 agacggcgtt gccgaccatg tggggcttgt gcttggcagg gacggcagcc gcgtctatac
    12241 cgttgagggc aattccggcg acgcctgcaa gataaagagc tatgacctta actatcaatg
    12301 tatcaaaggc tacgggctga tgaactggta aagcagcccc aaaaagaaag gagaatttac
    12361 tttatggcaa acaacaaaat tgaacgtatc aataaggaaa tcgcaaagac ccgcgagaaa
    12421 atcacagagt atcagaacaa gttaaaagga ctggaagcgc agaaaaccga agcggaaaac
    12481 cttgaaatcg tacagcttgt acgcgctatg cgactgaccc cgcaggaact taacgctatg
    12541 ctgtccggcg gcggtattcc cggcatgaac gccacacacg ctaccgaagc ggcagactac
    12601 gaagaacagg aggaaaatac agatgaagaa taaactgaaa aagaccatga ctgccctttg
    12661 tgccgccctt atccttatgg gcggtttttc tgtccctgcc tatgcacagg gcgcagccac
    12721 agagccgccc gcagaggacg cgaccaacga cagcaacgta attgtggagg aaaaagagga
    12781 aacgccgccc cttaccccaa agggaaacgc aacactggtt gacgatttcg gcggcaataa
    12841 gcagcttatc actgttacca ccaaaagcgg caactacttc tatatcctca ttgaccgggc
    12901 agccgagggc gaacagaccg tacatttcct taatcaagtg gacgaagccg accttatggc
    12961 actgaccgaa accggggaag ccacgaaaaa gccggaagtc tgcaactgta cggaaaaatg
    13021 cgaagccgga aaggtaaaca cgtcctgccc ggtatgtgca accactctga caggctgcac
    13081 aggcaaagaa cctaccccaa cacccacaga gcagccggaa gaacccaaag aaaaaggcgg
    13141 caatcccggc gcggtgcttg ccttagtcct ctttgtgctg cttggtggcg gcgcggcgtt
    13201 ctactacttt aagtttgtaa aaccgaagca gaacgtgaaa ggaagcaccg accttgaaga
    13261 ttttgacttt gaggattacg acgaggacga gccggaagca gataccgggg aaacttccga
    13321 agatgaagaa acggaggaag aaaccctatg accctattta ccgacaatcc ctttgaaaag
    13381 atgatgatac agaaaccgga ctatggcaaa ggggaaaaat ccccgccgga gctttcttcc
    13441 ccacgttgcg cgggctgccc ttacaagggg cagtcccctt gtgtggggta ctgtatcaga
    13501 aaactggaaa ccaaacgaca gaccgaacga taaaaggagg aagtatcatt gattttagtt
    13561 atcgcagaaa agcccagtgt ggcgcagaca atcgctgccg tacttggggc aaaggaaaag
    13621 aaagacggat ttctcacagg aagcggctat atcgtttctt ggtgcgtggg acatttagta
    13681 gggctttccg aagctgacgc ctacggggag cagtataaaa agtggagcta tgacagccta
    13741 ccgattttgc cgcaggaatg gaaatatacc gttgctgctg acaaggaaaa gcaattcaag
    13801 accctaaagg agcttatgca ccgggcagat gtttccgaag tcgtcaatgc ctgcgacgca
    13861 gggcgcgagg gagaattgat tttccgtttt gtctatgaag ttgccgggtg caggaagcct
    13921 atgcgccgct tgtggatttc ctcaatggaa gaagctgcta tcacagaggg cttttctcat
    13981 ctgaagaacg gcgaagcata cgacgcgctc tttgcttccg cactatgcag ggcaaaggct
    14041 gactggctta tcggtatcaa tgccacccgt cttttttctg tcctttacaa ccataccttg
    14101 aatgtgggac gcgtacagac ccccacctta aaaatgcttg ttgaccggga cgcagcgatt
    14161 accacattta agaaagaaaa atactaccat gtgcgtcttg ccttatccgg tgcggaagct
    14221 gcaagtgaaa ggctgtctga ccgttccgaa gctgacaagc tgaaagctgc ttgcgaagcg
    14281 tcaaaggcgg tatgcacttc ccttgtgaaa gagaaaaaga ccgcagcccc gccgaagctc
    14341 tttgacctta cttctttaca gagggaagca aaccgcctgt tcggatatac ggcaaaacag
    14401 acccttgacc ttgcacaagc cctgtatgaa aaaaaacttt tgacttatcc gagaaccgac
    14461 agcgcatttc tgaccgacga catgggcgat acggcggcgg gcattatcaa gctgctttgt
    14521 gggaagtttt cttttatgga gggcgcagac ttcacgccgg agcttgcaaa ggtgctgaac
    14581 agtaaaaaag tatccgacca ccacgcgatt attcccacaa tggagcttgc aaagactgat
    14641 attatcgcgc tgccggaaag tgaaaaaaat atccttaccc ttgccgggac gcgcctgctt
    14701 atggcgaccg ctgcaccgca tacctttgaa gcggttacag cactttttga atgtgccgga
    14761 cagtccttta ccgcaagggg aaaaacggta ttgtccgacg gttggaaaga gattgaccga
    14821 aaatacaggg cagccttaaa gaacaagccc gaaacggacg acgcagacag cgacacagaa
    14881 aagaccctgc cgccatttgt cgagggacag acctttgaaa atccggcggc aacggtaacg
    14941 gagcatgaca ccacaccgcc aaaacctcac aacgaagcgt cgctgctttc cgctatggag
    15001 cgcgccggaa gcgaggacac cgacccggac gcagaacgca aagggcttgg cactcccgcc
    15061 acccgcgccg ctgttattga aaaactggta aagggcggct ttgtggaacg caaaggcaag
    15121 cagctacttc ccacaaaaga cggtatcaat cttgtgtgcg tcctgccgga caccttgaca
    15181 agcccgcagc ttaccgcaga atgggaaaac aatctgacgc agattgccaa aggcaaggca
    15241 gaccccgccg catttatgga gggtatcgag gatatggcgc gggaactggt aaagacctat
    15301 ccgtttcttt ctgatgataa agcgcagatg ttcaagccgg aacgggaagc gttgggaagc
    15361 tgcccccgct gcggttctcc cgtctatgag ggaaagaaaa actactattg cagcaacaaa
    15421 gaatgtatct ttaccatgtg gaaaaatgac cgtttctttg aagaacgaaa agtaaccttt
    15481 accccgaaga ttgccgctgc actcttaaaa tccggcaagg taaatgtgaa aaagctctat
    15541 tctccaaaga cgggcaaaac ctacgacgga actatcgtat tggctgatac aggcgggaaa
    15601 tatgtcaact accgcattga gcttccgaag aaaaaataac tgaatagcaa gcataggaaa
    15661 agagtaccct tttccgtaaa atccctgctt tctctaccga gaacggcggg gatttttgct
    15721 tgttgggaag tgtcccaaac cctctgaaat cttgaaaaaa tatgtaaaat ctttggcaaa
    15781 aaggcgggcg cggggtactg aatgatgaaa ctggaaagag cagcgtccgc gctgcccttt
    15841 ggaaaggagg ttacacatgg caagtttacg ggacaccgta aaggactatc aagaagaatt
    15901 acgggacggt atcgcttggg tggcgttttg gaaaacagga cgttcttgga acgcagaaga
    15961 tttccacctt gaactgggcg actacctcta cccggaggac agaagccgca tggaggaaat
    16021 caaacaggct gaccctgccg ccgttgtggt aaacgggtat tattccggct atcttggcga
    16081 agatatgaac cttgacgagc tgaccgcagg ggtgcgccgc cactacgaaa acggatatag
    16141 caatatcggg gaatttatcg aagcacacga cgacaggctg ccgccggagc ttaccgagga
    16201 agcaagagcc gccgcccacg ctgcggggct tcctttctct gaaaaagcct accgggacgg
    16261 cgaagaaccc gacccctatc tatttgacgg gagcatgagc atggaggact acgaacttat
    16321 gcaccgcatg attgaaaacg aaaggagtga acgcatggca gaaacgattt taagcgggta
    16381 tctttctaat cttggaaagt acaccgaggg cagacctgcg ggcgaatggg tatcattccc
    16441 cacgactgcc gagcatttga aagaagtctt tgaccgtatc ggcatagacg gcaaaaacta
    16501 cggggagctg cacatcacag aataccagtc ctctattgcg ggactgacag ggaaattgac
    16561 ggagcttgaa agccttgacg agctgaacta cttgggcgaa cttttgaaaa tgcagtttga
    16621 cgacgaccgg gaaaaattta ttgcggctat ggcatacggc gaccatacaa gggatttgca
    16681 ggacattatc aaccttgcac aaaaccttga ttgttactgg ctttatccgt ccgtacagag
    16741 cgaggaagat tacgggcatt atctgattga ggaactggac gagttggagc tgcccgaaga
    16801 agcaaaaaac tattttctct atgaggaata cgggcgggac gctgctatca atgacggggg
    16861 cagatttacc gagcagggct atatctacaa caaccgcaac acctttacac agtggtatga
    16921 cgggcaggac gtgccggagg aataccgggt aacaccgcag cagcaggaac aggcagacct
    16981 tgacgctgcc gccgtacagc ctgcacttgc cacagagcag cccccggttc tcccgattat
    17041 cctatcttcc gaaaagcccg ccgacaaaat gaaagagatt accgaccgac tggaacaagg
    17101 aattttagag atttacgaaa gtgagcgtta cgccgattat ctgcgtacca tgtcaaaatt
    17161 ccatgattac agcctgaaca atacaatcct tatcgccctg cagggcggca atcttgtgaa
    17221 aggctataaa cagtgggaaa aggaatttga ccgccatgta aagccgggag aaaaagctat
    17281 caagatactt gcaccgtccc cgtttaccgt taagaaacaa gtggaaaaaa tcgacccgga
    17341 tacccaaaag cctgttttcg acaaggacgg gaaacctgtt accgaagaaa aggaaatcaa
    17401 gatacccgct tttcgtgtgg tatctgtttt tgatgtttca cagaccgagg gaaaagagct
    17461 tccctccctt acctatgagc tgacgggcaa cgtggaacag tatcaggatt tttttgctgc
    17521 ccttgaaaag acttccccct ttgctatggg atttgaagca ctaagcggta gcataaaagg
    17581 acgctgcaat tatgaggaaa agcgtatcat catcaacgag ggcatggagg aattgcagaa
    17641 tatcaagacc gcaatccatg aaatcgccca cgcgacactc cataacatag acaaagacac
    17701 gccagaacgc cccgaccgcc gcacccgcga ggtacaggcg gaaagcgtcg cctatgccgt
    17761 ctgccaacac tacgggcttg atacgtcgga ctattctttt ggatatatcg ccgggtggag
    17821 cagcggaaaa gaacttgcag agttgaaagg ctctcttgaa acaatccgca gcaccgccgc
    17881 aagtctgatt gataccatag acgggcattt tacagaaatc caacaggcac aggataagga
    17941 gcagaccacc gaacaggcac agcccgcgca ggaaaccgcc aaacagtccg aagcagaagc
    18001 agccgcgcag gagcttcccg aagaaacagc cccgatacag gaaaaagaag cacagacgga
    18061 gccggaagct gatacgggcg cgagcaacga agcaccgcag cccccacagc cggaacaggc
    18121 tgcacccgcc gccccttatt acactatcaa tgaagctgcc gccaaacgtg caaaggatat
    18181 gaacagcttt tccgattata agcaaggcag cgcaacagcg gaatacaggc attatgtaga
    18241 tgaagctatg cagcttgcag aacggcagaa acgccgggta gacccgatgt accatgagaa
    18301 aatcgacagc ctgcttgaca cttacgcccg gaaactggcg gcgaacatga acaaaggcta
    18361 tgagattgac gcgcgtgttc cctctattct tatcgcgggt ggctctaatt tccccacaag
    18421 gaagaaagaa aagcagaacg cagcccgcga cagcaattac cgggaatggc aggacataca
    18481 agggcttctt gataaaatcc gcagcaccgg catgggcggt atcagcgcag acgacccaca
    18541 ggcagtacag aagttggaaa agaaactgga aagccttgaa aaatcacagg aaaccatgaa
    18601 atccgtaaac gcctattacc gcaagcataa gacccttgac ggctgcccgc atttaccgcc
    18661 ggaggaactg gaaaaactga aagcagacat ggcgagcagt tggcatttgg aggacaagcc
    18721 ctttgcgact tgggcgttat ccaacaacag cgcagaaatc cggcgcgtga aagaccgtat
    18781 caaatccctt tcgcagcaaa aagaaatcgg ttttgtgggt tgggagtttg acggcggcaa
    18841 ggtggaagca aacaccgaag cgaaccgact gcaaatcttc tttgaggata agccggacga
    18901 agccacgcgg gaagccctaa aaagtaatgg cttccgttgg tcgccaaaag caggggtatg
    18961 gcagcggcag cttaccagta acgcctatta tgcggctgat tatgtcaagg cgattgcacc
    19021 ccttaccggg gaaaagccta ccgagttaca gcgggcgcat atccgggcgc aaaaggtagc
    19081 tgcacaagaa caaaccacac aggagcagcc gaaacaggaa gccccacagg acaaagacac
    19141 cttttccatt tatcagataa aaggcgggga cgaaacaagg gacttgcgct ttgaacctta
    19201 cgaccgtctg actgccacag gacaccgggt agacgcgaaa aactatacac ttgtctattc
    19261 cgcagagctt actccgggga cttcccttga agatatttat acccgcttta atatcgacca
    19321 cccgaaagat tttaagggac acagcctttc cgtttccgac gtggtggtgc ttcatcagaa
    19381 cgggcaggac accgcccact atgtagacag cttcggttat aaggaagtgc cgaagttttt
    19441 gcagccggaa aactatctga aaactgccga gcagaccacc gagcaaaatt acaacatgat
    19501 tgacgggcag ataaacaata ccccgaccgc cgcagaactg gaggaaaagg caaaagccgg
    19561 ggggcagatt tcccttgcag aatacgccga agcattgaaa accgataagg aacgcggcaa
    19621 gactgccaaa caggaaaagc cctctatccg ggcgcagctt aaagcagcga aagaacagac
    19681 accgaagaaa caggcaaaac agaaaacaca ggatttggaa aggagctgac cgatgaagtt
    19741 acaaaaattt gaaaatgtgg acgttatcgc ttctcttgaa gccataatga aacagcacac
    19801 cgctttttat cagagcgatt ttgagataga caaacagatt ttgcagaaag cggcgggaag
    19861 ccctatcccg gaggacagac ggcttttgtg gttttcccgc ccgtccggga cgtgctgctt
    19921 ccgggaacgg gacgtttttc taaaggacac aaggcagcat aatacatggc gattttacgg
    19981 ggaacagacc cgcgatacta tccttgccta tgcggtggaa ctgacaggca cagagcaggg
    20041 aaaaatcaaa ggcaatcttt atgaactgga ttatttgcag catttccggg aagtaatcga
    20101 aaaatccata cccgccgaca actacacgct gatttatgag catggggagc tgacaaagcc
    20161 tgccggacaa tattttgacg gggacactga cccgcagctt ggaaagttta tacgttttga
    20221 agcacagcca aacgacccgg aagccttgaa aatcctttta ggggaacaga agaaaaaccg
    20281 aacaccacat acgcaggggg attttcagtt acatattgcc gccctgcatg acagacggat
    20341 tgaaacagaa gcccgccgga ttgtggaaaa tgtaaaaggg cttggagaaa cggacagccc
    20401 cgaaaagacc cattgtgcgg tagaactttc cccctacttt gttccactgg caacggataa
    20461 ggacatggaa cggctatttt ccatgcttcc ttacaaaagt ctttcctttt ccacgttgga
    20521 gggcaggcat ggcgtttatg cgctgataga taaaagcgaa aggaataaag agatgagaaa
    20581 atcccgtccc tctgtccggg cacagttaca aacagagaaa tccccaaaaa ttccgaaaaa
    20641 gacggcaaaa tcaaaacatc acgaaatgga ggtatgagca tgattagact gaccgttgaa
    20701 gaaatgaacc tgttaagtat ttaccatgag ggaagcaaag cacagcttat ggaaaatatg
    20761 acggctgcgc tgccgttcat ggacaaggat atgcgggaac tggcgaagcg cacccttgcg
    20821 aaaatcgcac ctctgacaga aaatgagtat gcggagcttg ccattttcgc cgctgatgag
    20881 gtatgactgg gggtaagcgg ctcacgccgc cacagagccg gaaagtcaac agccttgtaa
    20941 aaaaggagtg ctgcaactgc gagcgcggac actgtatctt actggacgac ggggaggaat
    21001 gtgtctgccc gcagcttatt tcctattcac ttctatgcaa gtggtttcag attgccgtac
    21061 ttcctcttga taagctgctg tatgcagagc ttttcaaaac cgaggacaaa aagcgttgta
    21121 ccgagtgcgg cacgttcttt gtatcaaagt caaacagcgt caaatactgt ccggactgcc
    21181 ggaaacgcat tacccgcaga caggcagcgg agcgcatgag gaaacggcgc gcggcggtta
    21241 cgcagtaggg gttaaaaata cttgatttat ggaactttca gagtatgaaa atcaagcggt
    21301 aagggtttta taccttatct ccgaaaaata gcattctaca ccgtaacata cacccagatt
    21361 gcacctacac aaagcagggc gcagacagtc ttttgttggc tgtctacgcc ctgtcttttt
    21421 tatttctttg gcaagcattt atatgtattt gcaatccaat catcaaattt ctgacctttt
    21481 tcaaattcca ttacatcata catttctgct gcgattgttt tgaacgcttc tttgaacaca
    21541 tacaaatcta attcttccat tgatttttca cgtttgatac gcaaaaaaac tttagtaaag
    21601 tcttttgttt tgaaaccaat atctttacgt cctaatcgaa taggatttcc gcgataagta
    21661 atacccatag cttgtgcagc tctaaatgct tcttctttaa ctttataaac tttgtcatgg
    21721 agagcaaggc gcgtaataac atctttggat tgttgacaat catattgttt tagttcattc
    21781 aatgcagcaa gcctaatttt ccatgatgat ttattgtttg catctttgac aagctgacca
    21841 atattagcag gtgtttcttt tgtcatatct ttatcaaatc ctttcatcaa attttaatgg
    21901 ttttattata ccactttttg ctttccattt ctatatgtaa ataattgatt tgcttactca
    21961 atattcacgt tcttttctcc gttccggctc tttttccagt cttaaaatac tgtctatgtt
    22021 ctgcttgata atgtcgtatt ccttgacctg ttttttcagc ttgccataat tagcgtaaag
    22081 ggcttctttc tgtacttgga gtttcccgta ttcttcctgc atggcggcaa gattggggag
    22141 cttagtaacg cccgccgctt ttagtgtctt tactgccgct tcatggagta tcagactgct
    22201 ttcctgtttt gccctgtatg cgtccttatc ttttgccttg cggtatgctt cataaacagg
    22261 ttttgtcttt tggtaggtgg caacgtgctt catcagcacc gccatatctg caagacgttt
    22321 tcccacgctc tttaatgcgt ctgctgtctt ttcattttcc gcatttattt cctcaatccg
    22381 gctgactaaa tctgcgtact gctcaatctt atgttccgtc aaaaaattca tagtttttgc
    22441 agccagtttc agattatgga ttttcgccca ctgttcatag ccccggctct cttgtgcctt
    22501 gatactgttt tcaatgtcga taagcagcga tacgccgcgc tgctctttgg gagctttcgc
    22561 tgcctttgtg cgtttgccct ctatccgttc tcttatggct tcctctgtat aatctgtacc
    22621 gagagttttc agacgggtaa agcgttcctg tccgggagtg cggcaggaga tatattttcc
    22681 cgactttatc tcataacccg ctgcctgtaa ccgctgcaac aattcttcaa aacttgctac
    22741 ttgggggata agtgtatcaa cggcaatttt cagcttgcct ttccaacttg tcccggcttt
    22801 ttcagcttga tattccgcat agctttttcc cttactgcct ttacccggaa caacaacaga
    22861 cagcccgttt tcccggcaca gcttatcgct catgttccgt atgccgtagt agctgcgctt
    22921 attggaattg tacttatggt agtcaacaaa attgaccgca caaaaaatga tatggttatg
    22981 gatatgccct ttgtctatgt gggtagtcaa gacgtattca tgctgtccct ttgttaccgc
    23041 gtcggcaagc tgttttccga tttcgtgggc tttctcataa tccacttccc ccggctcaaa
    23101 ggactgtatc aaatggtggg cgagattgtt tcctttctca atggcttgtg caagtgtaaa
    23161 tccaaactca atgtctgccg tttcataact gcacccaaag gaggacacaa gcattttccc
    23221 gtctgtttta tccgggtttt ggatatagtc aagggctttg ctcaacgtgc ttttaatagg
    23281 cttaatcttt gtaaccgcca tatctctgca agcaccccct ttatttcctc tatgtcctct
    23341 tggtagacgc tgcctgtcgc attgacacgc tttgcaatct gattgatgtt gaccccgatt
    23401 ttctgtatct ctgctgtcat ggcttttata tcgctatggt ctgtctgaat gatatagccg
    23461 tcaatggcaa tcttgcgaag atacgccgcc atgtttcggg tgggaacgag cttcattttc
    23521 tgttcaatca atgcccgttc ttcctctgtt acatagaatt tgatttgtac ttttcttttg
    23581 cgtccgttca tgcaattgct cctttccatt ccgagggttt gggacacttc ccaacaagca
    23641 gttttcaacc gacgcaccgc aggacgggag ggcgaaaata cggaaaaggg tactcttttc
    23701 ctatgcttgc taagaaagtt ttttcctcac ttatcactac aacaaaactc ccagtatgcc
    23761 aaaaaagcgc aaaagaaaaa cgccgcaatc ctgcgacgct tcaatctctt tatgcagaca
    23821 aaaacgaggg aactttattc ccccgtcctg tcgttgttgg cttcctctat gccttttgca
    23881 gtagcagaca tgatttttaa gtccgtttcg ctcatagtgt caagcatggt atcgagctga
    23941 cggcggcgtg tggacttctc ctgttcccgc tcagggaaaa agaactggtc tactgataca
    24001 tcaagcagag ttacaagttc atacaaaatc tgtaaacttg ggtgttgccc gctgttctca
    24061 atggacgcga tatatcgggg cgcaatattc agcgtatcgg ctaactgatt gcgtgatatt
    24121 ccctttgctt ttcttgctgc tttaatggct tgcccgaaag ccttaaaatc gaatttttct
    24181 ttactctgtt tcataatcat ttcacccaac tacattttac tgttcctctt ttctttgaga
    24241 tatgattaca cagaacatag tattgactga aatagagcat attatattaa aagcagcgtt
    24301 gtctttttga gatgaaaatg ttatactgac aataatccct atttgattga aagaagtgat
    24361 ttatatgtgt atcaacacaa aaaagagaaa caaagatttt ctccatgcaa agccagtaga
    24421 ttgcgacggt tgcatggagt aaaatagtcg cagaataaat gctggctttg taacttgact
    24481 atcataatca aggaggaagc ctgcatgaaa tataaaaatg cacaacttat tcttccggac
    24541 gcattggtaa aagagctaca aagttatgtt caaggcgaat atatttatgt tcctgtcgaa
    24601 caggagcagc aaaagcgttg gggggaagtt tccggttaca ggaaagaatt agagcaacgt
    24661 aatcagaaga taaaacaaga atatcaaagc ggtatttcta taaattgtct tgccgaaaaa
    24721 tattgcctat ctttatatgc tgttcggaaa attatatatc aaaagtaagg taaggggctg
    24781 ccgagtgtgc agcctcttat ttttatacag attggttcgg tattatatag agtatagaaa
    24841 aatttttcaa cgaactgtat gataaagaag aaatatttga agtacatggg aggagggaac
    24901 tattatgtgt acccgatttg tttataatgg gaatgacatg attacaggat ttaattttga
    24961 tattgacctt gcagtatgga aacataaagt gataaaagaa aaagaacgct tttatatagg
    25021 tattttacga ccggacggta cataccactc ttatcatggt atcaatagaa atggaaatgt
    25081 tggaacattg ttatatgtac atggcaatcc tgccggaata tatcgagata attctgactg
    25141 tataacgatt gcagacttaa cagaacagtt tattaaagcg caaatttctt ttgatgaggt
    25201 actccaaatt gtaaagtcaa agcaaattac ctatgcgccg gacgcaacaa tgcaggcaat
    25261 gttatcagac agtcatggac atgtcttaat cattgaaccg ggaataggct ataaagaaga
    25321 atacgaacaa tattccttga taacgaacta ttctttgatg aagccggaaa gtacaaaatg
    25381 ttttatcgtt ccgggggacg atagatatga acgtgctttg aaaaaaatag aaaaatatgg
    25441 tcccgatttt tcaatttcag atgcaattca tttactttat gatgtacgtc aagagggtgc
    25501 atgggcaacg agagtttctt tcgtgtattc tgccaaagag caaaccgtat attatgtaga
    25561 aaataaccat tttgaatgta ttcaaacatt cacttttccg ttagagcgat aagggaggaa
    25621 ccattatgtt acagaaaatt tatccacgtt caaaagataa agaaacagta tatcttaaaa
    25681 gtgttatcac taaccctaat atcatagtgg gcgattatac tatgtataat gactttgtga
    25741 aagaaccaaa agactttgaa aaaaataatg ttttatatca gtaccctatc aatcaagaca
    25801 aattgataat tgggaaattt tgttcaatcg cgtgtggagc aaagtttatt ttcaatagtg
    25861 caaatcatac attatcgtcc ttatcaacat atccgtttcc tatttttttt gaagaatggg
    25921 gattagacgt aaaagacatt acaaaggcat gggataataa aggagatatt gttgtcggaa
    25981 atgatgtttg gattggttat gaagcagtca ttttagcggg cgttacgatt ggcgacggtg
    26041 ctattatcgg ggcgcgagcc gttgtaacga aagatgtccc accttataca atcgtgggag
    26101 gtgtaccggc aaaacagata cgaaaaagat ttaatgagga aacgattgat acattgctca
    26161 aattaaaatg gtgggattgg tctaaagaga gaatatctaa aaatattgcc gctattcaat
    26221 ccggtaatct tggatattta ttataaagga aacacagaca atatttctct tgacttttac
    26281 tatcaataat agtactattg ataatagtaa aaaggaaagg agaaacaata tgtcatcaat
    26341 agatttagtg gtgcttggta tcgtgttaga aaaaccgcaa agtgcttatg acatacagaa
    26401 agatgtagaa tatcataact tatcaaagtg gacgaaaata agtgtgccgt caatttatag
    26461 aaaagttctt caattaaaag aaaaaggcta tttagaaagt gatattgtaa aaggagataa
    26521 atttgccgat aaagcgattt actctattac agagaaagga aaagaatatt ttgaaaagtt
    26581 aatgtttacc tatgcttctc aagatgttcc tctcttattt gattttaatg tggtaattgc
    26641 aaatttgaat aaagttagtt caaatgaagc gattaaactt attgctcaat taagagaaag
    26701 tataaaaatc tctgctaaag ctaatgaaga ttatgcaatt caatatgcta ctatcccact
    26761 tgtagggaga acgatttttg aacagcagaa acttctctat aattcacttt tagaatggct
    26821 taacaatttt gaagctcaaa tgagtaagga atgatgttat gtctgtaaaa agtagcttga
    26881 cggtcatgtt tgaagctcca ttttggattg gcgtatatga acgatttgac gagggatatt
    26941 atgaagtttg taaaatcact tttggtagtg aacctaaaga ctatgaagtt tacgattttt
    27001 tactaaaaaa ttggaatagt cttaaattca gtccccctat caaatcagaa ataacagaag
    27061 aacgaaaaat caatcctaaa cgtatgcaac gagaaatcaa caatcagtta caaaataaag
    27121 gaatgggaac caaagcacaa caggcgttga aacttcaaca tgaacaaaac aaaatggaac
    27181 gaaaagttaa aagtaaagaa caacgggaag ctgaaaaaga acgccagtat gctttgcgtc
    27241 aagaaaaacg aaaagctaaa catagaggta aataatgatg aatagtgaaa attggattta
    27301 ttgtccggtt tgcaaaaata aaacacgact gcaaatacgg gaagatactg aattaaaaaa
    27361 tttccctctg tactgtccaa agtgcaagca agaaacccta atcaacgtct ataaactaaa
    27421 tatttcagtt atcaaagagc cagacgcaca gacgcagagc cgataacaca tgaggatatt
    27481 tccttgtggt tatcggctta tttttccttt atatgttaga ttttaaaaaa gttgcgtcca
    27541 ttttaaaaaa gttgttgaaa atcaatttaa ttgcccttac gattgattta gaaattctga
    27601 atatggaggg acagcattga aaattgaaga gtttaaaaac attacaatcg cgtatatacg
    27661 acgaacgggc aattatggct tcgagaacaa aatctttatg gaaaatttta aagaatattt
    27721 aagagagaaa gaacttttag acaaaagcag tgttatttta ggaatagcat tagataatcc
    27781 cgctatgacc gataaaaata aattacggta tgatgttggt cttatagtca acgggaaccc
    27841 cgatatagca ttagatattc gcaaaattcc agacggtata tatgctgtat ttgaacttcc
    27901 acatacggaa caagacatta ctgctttttg gagcaatata cagaaattag ttggtagttt
    27961 atcagtggac gaaacaaagc cagtaattga gcgctatcct gccgacaaag ttgcaaaaca
    28021 tttatgtgaa ttttgtatac ctctgaaaaa actttcttaa aaattggtaa aaaattcaag
    28081 ctgcctaacg gtaataaaaa aaaccgttgt tacggcggca acttcctcat gcgcctaatt
    28141 aaaatataga ttgcctaacg gcggttttga aataacaatc aaagccgccg ttttcttttt
    28201 caaaaatgag attgcggggg gcgtattaaa gtcgcccttt tttaaggata tggcggtatc
    28261 aaggaggtac tgtcatgtcc ttttttatct atcattcccc acctgacaat tacaacttgt
    28321 caaaaaaagc cattatccac caacgggtta ttccggctat gtagatgaac tgtcaaatca
    28381 attaaatact gctgttattt cctatgcgtc tgtctgcatt ttgcaggcag gcgcatttcg
    28441 cattttgcag aagatttttc aaaaattttg ccctcttttt ggcaaagcaa aaagtcgcct
    28501 gtattatccc gcgaaaaggg gaggtactac cgcctttcgg cagaaaggag gtgaacacca
    28561 tgacacctaa tcgcagggaa tttgaaaagc aatgtacgtt tcaaaagttc tgtaaatcag
    28621 tgctgcacaa tgaagcgtgc aacgcccatg aagaaattcg tcggcgcaga gttcgggaag
    28681 ttactttttc cgaccttgcc ttgtatgagg aacggcagct ttataccgtc gataagtatt
    28741 ttcaagacga agaagcagag ccgtcttatc aaatggcagg aaaagaaata accccaaaac
    28801 tgctgcttga agctatccgg gctttacccg aagaacggcg caaaattgta ttgttgtatt
    28861 actttgaggg attaactgat atagaaatcg gaaagcagct caatatctca agaagtacgg
    28921 tacagtatcg ccggacaagc tcctttgagc agttaaaaaa atatttggag gaaaacgctg
    28981 atgaatggat tgaatggtaa accgaccgag tacccggaaa atgcccttgt tccctatcct
    29041 gttattttgg cggcgagcaa aggcgacccg aacgcaatga agattgtatt gcagcatttc
    29101 agcggctaca tagcaagtct ttccatgcgg aagctctatg acgagcgagg aaatgtttat
    29161 tttggagtgg acgaagaaat acgcgaaagg ctgcaagcaa aactgatgag ggcaatcctc
    29221 acatttaggg ctgaataaac caacgcggta ttggaacgct tccccctttt ccgttccatg
    29281 tcgcagaaca gccctctgct ctttgacaaa gaaagcggcg caatagaacg gcgacgcagt
    29341 ataggacaaa tcagatacat tcgatatatg gggagccgtt gggctgatac gccatgaccg
    29401 aaaggaggga caaaacgagc gagaactatc agcgttccat agcagactta gcaactctgc
    29461 cgccacaatc catatatcgg tataatgata ctcctttacc gccgtagtcc gagcgttaga
    29521 agcgtcgcag gcaacgggta gagctgcatg agaaccatgc ggaagtgaaa ttcttgtgag
    29581 gtttgctaaa accgtctgaa ctgtctattt ttaccttgta atagtgtact tgctgtcttt
    29641 cataagatgt acggaatacc aaagggggta tattttatgg aagataaagt ttcttatatg
    29701 attgataaag atgaaatcaa tcaacagaaa atgcaattag ttgtaataaa tcgtcgccca
    29761 caatatttac agaaaccgca ggaagttgcc aaacgagaaa tcgcaaggca gctttttcag
    29821 atttttcgga aatatgaatg atgtaattga aggactgtct gttcaatgct ataatataag
    29881 tgtgggcggc ttatgtcata acgtcttgtt cggaggtaac gaacatgatg tatgacgcat
    29941 tatatggacg ccagtcaatc gaaaaaaaag acagtatatc cgttgaaagc cagcttgaat
    30001 attgcaggta tgaaactcat ggcgaccctt atatcgaata tgccgataga gggtttagtg
    30061 ggaagaatac gaaccgaccg gattttgaaa aaatgatgaa tgatattcgg gcagggaaaa
    30121 ttaagcgtgt aattgtttac aagttagacc gtattagtcg ttcaatcttg gattttgcta
    30181 atatgatgga agtgtttcaa gaatatcatg tagaatttgt ttcttcaaca gaaaagtttg
    30241 atacttccac acccatagga agagccatgt tgaatatttg tattgtcttt gctcaactgg
    30301 aacgagaaac aatacaaaaa cgtgtcactg acgcttatta tgcaagaaat aagaggggct
    30361 tttatatggg gggacgtatt ccttatgggt atcgcttaaa ggaaactatc attgacaata
    30421 tccgcacttc catgtatgaa gaagtcccgg aagaaagcga acagctaaaa cttatttatt
    30481 cgttgtatgc tgacccggct aattctcttg gcgacattat acggtatctc aataagcatg
    30541 gtattaagca attacgcgga ggaaattgga cttctgcaag aataagtgaa atgctgagaa
    30601 atcctgtata tgtggaagct gatattgacg tgtataactt cttcaaaagt caaggagcag
    30661 atgtttataa tccggcaagc gattttacag gttataatgc ctgttaccta tataaaggaa
    30721 cggtatcaac aacaagaaaa cagtgtgacc ttacggacaa agaaatagta ttagcaccac
    30781 ataaaggctt tatttcttct gccacatggt tagcttgcag gatacgctgt ctaaacaatc
    30841 gccagtcaac acaaacttgt aaaccgaaga actcatggct tacaggaaaa gtaaaatgtg
    30901 gaaactgcgg ttatgctttg gtaattcgga aagcaaaaac aaaatgggga cgatatttcg
    30961 tttgcagtca atcgggacat agcggtaact gtaaaggaac gggaagcact gtttatgcag
    31021 acgttttaga ggaatatatg ttaaaagcca ttcgcgaaaa gctgtctgaa tttaagaagc
    31081 tatcagatga agaagaaaac aaatctgtac ctaaagtatc aaagaacaaa atccgtttga
    31141 cacaaataga cgaggaaatt aacgacctgc tttccaaagt aggaagtgca aacgctatct
    31201 tgatgaagta catcaatgat aaggtttccg agttagacac cgaacgccaa actttacagg
    31261 aagaaatcat ttctcttact tgtacgcata cagaaaacaa aatgggacaa ataacagacc
    31321 atgtaaagaa atgggataac atttcctttg aagataaaca ggcagttgtt gacgctttaa
    31381 tcaaagttat caaggtggca aacgggaata ttgaaatcac atggaaaatc taaggcggtt
    31441 ttatccgcta tcatttttga ggtaaatcta cttcaatctt cccgtttcgg tgaagcatta
    31501 atggatgttt atgagtttac agagtgcaag catcagtttt aatgaataat taaaagtgaa
    31561 tggagaataa gcatagttct aatgaaggat taaaagtgaa tggagagtaa gcatcatttt
    31621 taatgaagaa ttaaaagtga acagagagta agcatcagtt ttaatgaata attaaaagtg
    31681 aatggagagt aagcatcatt tctaatgaag aattaaaagt gaatggagaa taagcatcat
    31741 ttctaatgaa gaattaaaag tgaatggaga ataagcatca tttttaatga agaattaaaa
    31801 gtgaatggag aataagcata gtcctaatga agaattaaaa gtgaatggag agtaagcata
    31861 agttctaatg aagaattaaa agtgaaaaga gaataagcat aagttctaat gaagtattaa
    31921 aaatgaaaag agaataagca tcatttttaa tgaagtatca aaaataaaaa gagtgtaaat
    31981 attagctctg ataaactatc aaaataagag gtaaaagttt tagttgattt cttttatctc
    32041 ttatttttta ttgattaaac agattacttt gctatttaaa tatattattt tagcaaaaaa
    32101 agtccaatca aaagttcaaa gtattaccat agttcaaagc attgccgttg ttagtaagtt
    32161 ttttacaata ttttttattt actctttgga taatcaaaag aaataaaaaa tcatatctct
    32221 ttttttatat ttctgtacac ttttggagaa tatcccgttt tttctttaaa acatttacta
    32281 aaatagatta tttgatgaaa aacaactttt atagcaatgt cacttattag ctcatttgtg
    32341 ccttttagaa attgagttgc ttttaataaa caaaactcag taaaatattt ataaggtata
    32401 gtatttaaac ttagttcaaa tcatctggag cactctgatt tattgatatt accactgctt
    32461 gatagtactc caaaattaag ttttcacaat agtacccttc aatataatgt aaaacaatag
    32521 tatttttcaa tataacgtaa aattttttgc atatggatat taattatatt tttgtgtttt
    32581 attggtggca aaacaatatt ttttatcata ataagccaaa ggaaagaaac agaaactaat
    32641 gcttcataca tatacagttc atttttactt ttttctaacc ttattaatcg ttgtagaata
    32701 gaaaacactt tattgcgcca attatattta tgtgtaaaat gataaatagc gaattgttcg
    32761 ttttctgtta ttctatctac taacgatttt actggatttc taacataaaa atacttttct
    32821 tttttacagc ctattcttac ttttcccatt tgaaagtatt atgatattac ttgatgctat
    32881 atcgatattt ttttggtcta tttagtgata aaattataat atacacttct ataaaagtta
    32941 atacagtagg aagcttaaat gtatgaattt tatattcatc aaagggaaag ggaaaaaagg
    33001 atgaacagat gcaggtaaat ataaaactaa tatgatatga ggatagatat tataacgaaa
    33061 gtgtagttag aaggaaatta tattagtatg tttttacata atggtagata gaaaagaagt
    33121 gtctaatgat ttgagtgaag ttttcagaat ataaggagga attgtatgca atatattagc
    33181 tattaccata gtccaattgg aaatattctt ttagcatcag ataatattgg gttaactggt
    33241 ctttggtttg agaatcaaaa gtattatgct tataatcttg accaagaaca tcaagaaaaa
    33301 gaattgccaa ttttcgagca gacaaagaaa tggttagata tttatttttc gggaaaagaa
    33361 cccaatttta caccatcact ccatatggta ggtactcctt ttcagactac agtgtggaaa
    33421 attttacaac aaataccata tggtaaaaca atcacttatg gagaaattgc atataaagtt
    33481 gctcaacaaa aaggaatatc taaaatgtca gcacaagcaa tcggtggtgc agtagggcat
    33541 aatggaatct ctattattat tccatgtcat cgtgttgtag gaacaaatgg gagtttgact
    33601 gggtatgctg gtggaattga tagaaaaata aaattgttat ctttagaaaa agtatctgtg
    33661 caacattatt ttatcccaaa gaaagggagt gcattataaa gccattaaat ttagaaattc
    33721 ttaatcattt atttgatata caaacatcta attttgaaag caataacttg taattttaaa
    33781 aaatgattat ttaaactata tgttatacaa ccttattcct agtaaacatt atacaacttt
    33841 agaggtagtt tttagagctt gtattttgga agtttatttt catttttcgt gtgagtagtt
    33901 atatgtttag atgcagtaat ttatatgcta caaacaggaa aacaaggagc agacaaaaaa
    33961 tatttagata atatgttttt tgtgaaaggt tatgttgaag aacttctatt tttagacaac
    34021 agttatgata ttgtattttc atgtattgta tttcatcatt gtacaaatgt tcaaaatata
    34081 ttttgtatat tttggaaatg gtaagagtgt taaatgtaag gggaaaattt ataatgtttg
    34141 atacttaagc tactcattaa gtattaagaa ccatacaaga taaggttgaa atttatatgc
    34201 ttcgttttat gtaaaaaatg taagtgagtt agaaatgaaa gaattattta taaaaaatag
    34261 attaagtatt ggaaaatatg aaaaatagat gttgaacaaa acttagtcga ttggttaaat
    34321 ttaaccaaac acttaaagta tcaaaagaaa aaattattac tcttaagcaa gaagatataa
    34381 atggaaaaat gaaaacaaga ttttatcctt ttataagtga taaggggatg tgttttaatc
    34441 aaagatggac ttttatttta ggctgaaaaa ttatataact atattataga atataaggga
    34501 gatacacaac tttttagtgt ccaatctccc ttatttttta ttattatatc aagactcatt
    34561 tagtcgtgtt aattttagga taaaatgagt atttttttaa taaattattt ataagtaaag
    34621 tgtgttgtcg gataatcagt atttctgtat aaaatttggt ataactttaa agaagtatgt
    34681 gaaattttca ggtatttttt actatagtat attatttaac tgattttaat ttagcaatat
    34741 cattcgaatt cttagatgtg actatctcta tattatttaa atcattttta atatctgatg
    34801 tatcttttac taatgaagag gtatgtttaa tcactgtatc taatgtattt ctgttaattt
    34861 ttacatctga cttaatttct gtaacatcac tctgaatagt atcaagttta ctactagttt
    34921 caacttgtcc agtttttaag tctttaatat caggttccat attgtctaac ctactattga
    34981 cttctttaat ttcaacttgc atatcagtaa tactgtcttg catactatta atagtgccat
    35041 ccatactact gatacttcct tgcatatcgc taatagtgcc attcatacca ctgatactac
    35101 cttgcatatc tccaatagtg ccttgcatgc cactaatagt gttttcgata ccattgatat
    35161 tgccttgcat actattaata gtgccttcga taccattgat attgctttgc atatcgctaa
    35221 tagtgccttc gataccattg atattgcttt gcatatcgct aatagtgcct tcgataccac
    35281 tgatactacc ttgcatatta ctaatattac cttgtatttc ctgtaataac tctaatattt
    35341 tttcatccat cactatcaca ctcctgcttt attattataa cataatttag gtgttatatt
    35401 ccacaaacgc tatgtcatat ttaattttta atcatataat tatctgctat tcaaaacatg
    35461 gttaaatata tctatattga gaactttttt attaatgaat cttatgtatt gtctaagttt
    35521 ctaagatact gtaataagtg tttttgaggc atgtgtggtt atatttgtat ttaaaactgc
    35581 tggtaatatc atatactttt aaatatacct taagttattt atattgatta cttgtatttg
    35641 aatattttga ttagtagctt cctttttatc tctttttatt cttagtttta aactttcata
    35701 tttccttgaa aatttattgg caatgaaagt gcatgaattt tttagctatt ttttatgtta
    35761 caatatgaat atataacaat tcgacaaatt ggatttttga aaggagtaaa atgttatgaa
    35821 aatgccaaaa gagagtattg atacgattat gtttgctcct tgtggaatga attgtatggt
    35881 ttgctataag cattgttatc acaaaaagcc atgtgctggt tgtttgaatg gcgatacagg
    35941 aaagccagaa cactgccgta agtgtaaaat aaaggattgt gtctgtcaaa aagggttgtt
    36001 ttattgtttt gaatgtttca attttccttg taaactcata aaaaatcttg aaaaaagtta
    36061 taacaagaga tatcaagcaa gccttatgga aaatagtaaa tttgttcagc agtacggttt
    36121 agagaagttt atgcaaaagc agaaggagag atatacttgt tctaaatgtg gaggaattat
    36181 atctattcat gatagggaat gtagcgagtg tcaagaaaaa gtgaaatagc taaatcactg
    36241 tttatcaaga tagaaaaaat tgtaatatat ataaaggtgg attatattga ggtggtatat
    36301 agtgataggt ttaaaatgtg gtatggttaa attattggaa catcagatga tatgggataa
    36361 aagtgcaaaa gatgtcatta tattattgaa aagtatatgg gataagactg ccattgatat
    36421 tcaacacatt ggaagtactt ctattcccag tattagcgca aagcctatta ttgatattgt
    36481 tgtaggtgtt gcttctttag aggaaactaa attatacctc gaaaggttag agcaatgtgg
    36541 aatcgttttt cgaggtcagg atgtaccaaa acaattactt tttgctatgg gagattttga
    36601 gaaaaatact cgtactcacc atattcatgt tgttgaatgg aatagtgttg catggaataa
    36661 ttatatcaat tttcgagatt atctaaatac ttttacagac aaagcaaaac tctatgatag
    36721 tcataaacaa aaattggcat tacagtttga ggacaatcgt aaaatctata cacagagaaa
    36781 gcaagaacta ataaatattt tgctggaaga agcacgactg tggagaataa atacctaaaa
    36841 gaataaattt acatttattg agaaattgag caattatttt cttatattta gtaaataaaa
    36901 atctattttt gttgattaaa aaatatctgt acacactcat gactttagtc attggagatt
    36961 cagattgtgt agaattattg gatgaaggag gaacagtatg aaaaaggata catctcatat
    37021 tatcaaacgg gcagagcact ttcaggtaat tttgattggt gaaggactta tggttggggc
    37081 tgtggctggt ttgattgtgc ttttatacag gatactttta gggcaggctg gtacttggct
    37141 tagccaaatt ttaaaatttg tagaaggttc tacaataaaa ataatagctt ggtttgcagt
    37201 acttgcagta cttgcgtgga ttgtatcaaa gttggtggac tgggagccaa tgatttctgg
    37261 aagtggtatc cctcagcttg agggggaaat gacagggaaa ataaaacaag tatggtggcg
    37321 agtgttgcca acaaaattta ttggaggatt cttatcactt atgggtggtc ttgctttggg
    37381 aagggaaggt ccttccattc agcttggtgc tatggcaggt aaaggtattt ctagagctct
    37441 tgaccgaggg aagacagagg aaaaattcct gttaacctgt ggggcaagtg ctggattatc
    37501 agcagccttt catgcaccac tagcaggtgt tatgttttca cttgaagaag tccataaaaa
    37561 cttttcagta tctgttttaa tttctgtgat gacagcatct ttgacagcag actatatttc
    37621 agccaatttc ctaggaatgg agtctgtatt ccagtttgat taaaaaatag ctacgcacac
    37681 ttgtgacttt agtcatgagt tagtagctaa aatagtcagc atatagggaa acctatatgt
    37741 agagatagga tagaacctat ccaatactac ttgaattgct ggaaacccct aaagctaa
//
LOCUS       DAEORM030000041        33126 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.041, whole genome shotgun sequence.
ACCESSION   DAEORM030000041 DAEORM030000000
VERSION     DAEORM030000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 33126)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33126)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 33126)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33126
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.041"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     regulatory      224..267
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            368..1336
                     /locus_tag="KRH23_002535"
     CDS             368..1336
                     /locus_tag="KRH23_002535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside hydrolase"
                     /protein_id="HHS5225813.1"
                     /translation="MEKRKVIIDCDPGIDDSLAILLALNSPELEVIGITTCCGNVPAN
                     IGAENALKTLQMCSSLNIPVYIGEEAPLKRKLVTAQDTHGEDGIGENFYQKVVGAKAK
                     NGAVDFIINTLHNHEKVSIIALAPLTNIAKALIKDKKAFENLDEFVSMGGAFRIHGNC
                     SPVAEFNYWVDPHGADYVYKNLSKKIHMVGLDVTRKIVLTPNIIEFINRLDKKMAKYI
                     TEITRFYIDFHWEQEGIIGCVINDPLAVAYFIDRSICKGFESYVEVVEDGIAMGQSIV
                     DSFNFYKKNPNAIVLNEVDEKKFMYMFLKRLFKGYEDIIDSVEGVI"
     gene            1338..1901
                     /locus_tag="KRH23_002536"
     CDS             1338..1901
                     /locus_tag="KRH23_002536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HHS5225814.1"
                     /translation="MKRKICVKTITLIAFGISINIIGAFIAMGLRLPVYLDSIGTIMI
                     ASLLGPKYAVVTGVFGSLISGITFDVYSLYFAPVQISTGLLAGIAFKKNFLRGLKTPL
                     GVLLFAIPTSIISSIISAFLFGGMTSSGSSYIVQILKVLGLGDVFSVFVTQVFTDYGD
                     KLLAVVLVNLGLNAVPKTLKVSLTGGK"
     gene            1909..2598
                     /locus_tag="KRH23_002537"
     CDS             1909..2598
                     /locus_tag="KRH23_002537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HHS5225815.1"
                     /translation="MDRYSEITNKNQREIVLLKGFPCIWGKCSFCDYIDDNSNLEEEM
                     NKLNLKVLKNVTGKYGVLEVINSGSCFELPKDTLEKIKCIIKEKNIKKLFLESHWSYK
                     NRLKEMREYFEIPVVFKIGVETFDNDFRNNILNKNANFKTPQDVKEYFDSPCIMVGIK
                     GQTKEMIDKDIEIILNTFEKATVNVFINNSSSIKRDEELVKWFVSKYKFLDENPNIEV
                     LYNNTDFGVGD"
     gene            2725..3453
                     /locus_tag="KRH23_002538"
     CDS             2725..3453
                     /locus_tag="KRH23_002538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HHS5225816.1"
                     /translation="MMFDRGKWNKLDYNELLEYMMSIQDIKYRDFNKKLIPGTENIIG
                     IRVPNLRKLSKEISQGNWKEFLEVAEDTYYEEVRLQGMVIGNINSNFEETLYYVKRFI
                     PKIDNWSVCDGFCSDLKSMKKYKENMYDILKKYVYSKNPWEIRFALVMFLIYYVDDKH
                     IKEIFEYCNNIQSEEYYVKMGMAWLLSICFIKCEEETFLYIKNNNLDDFTYNKMLQKI
                     IESNRVDLEKKNIIRSMKRKTRRC"
     gene            3467..4141
                     /locus_tag="KRH23_002539"
     CDS             3467..4141
                     /locus_tag="KRH23_002539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HHS5225817.1"
                     /translation="MNNNEDRIDKFLELQSKGFKFAEIAQNLKISQSTLRTFLNKKGY
                     KSEKGKYILKDELNYNKSLDNRNLEEEKAKEYEKSKKNTISNRKKVSTKKKISNEKAL
                     SKSVEQIEFNDTGLKNAKPKQNVKPKKDRKINITQEDLDKLCEVYDWYLEVKDYNIKP
                     KKVSNKKDVHIDDEHIDELKTTRIRIDKEVWNDFERLCSNSNFEKHQILTQALKEFMK
                     KYKNLL"
     gene            4167..5003
                     /locus_tag="KRH23_002540"
     CDS             4167..5003
                     /locus_tag="KRH23_002540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5225818.1"
                     /translation="MNEIVKKSISLMIILTIFIFMLTACEKDEQPDSVDIQTEDKNEI
                     KIDEGNAKVLNIGKSEIINIDEGDKVDTSTKVENNSTFNISNVELIYNEYDENKKIIS
                     SDSKALLDMTLMPGKVAYIECGHKTFVKGVEVYAYEYEAEGKIVYVNLKENTINIRNN
                     NIKLENSSQYEVLSTSELKKVNESNEGITYQVKVKNSSSKDLGNIILKTAEVNENGEY
                     LTVNRVPSYKILKPSEETDIDILCSTKAKSVEIVGYTYDDIKEKANVDIDLKSHKVKI
                     DK"
     gene            5019..5690
                     /locus_tag="KRH23_002541"
     CDS             5019..5690
                     /locus_tag="KRH23_002541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HHS5225819.1"
                     /translation="MKVLIVEDNKILLESVVEELSKHFETEKCEDGEEALYLVNQNIY
                     DLVILDLMLPNINGFDILKKMRVNNIDTPVLILTAKETLDDKVEAFTIGANDYLTKPF
                     YMEELVARVYAILRTNGKIKERNGLEFKALYLDTLEKRVYIEKEEIKLQNKQFNLLEY
                     FVLNKGSILLKEQIYDRIWGIDSDATIEIVEVYVSNLRKKLSKYGYDKYIKTKRKVGY
                     IFDDK"
     gene            5680..6912
                     /locus_tag="KRH23_002542"
     CDS             5680..6912
                     /locus_tag="KRH23_002542"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HHS5225820.1"
                     /translation="MINKNVFTSTKNHLIKMYIIVVGSFLIIFSIFIYSYFRGLTYSG
                     IDSEINDELEYIVSQFKRTSFLNPIRLKDPKDMVYVYEDGRISYYTQNEYFDELLPDR
                     RLDKKNSFFKYTENGYTFRELNVDVGRYQIQIIRNIDSEMNSLRQLTSVLIIGILISV
                     IITYFVAVYLTRKALIPIETAWKNQAKFIQDASHELRTPITIVSSKLESMLKSPESTV
                     NDEVETIATAMKETRRLKKMITDLLSLTKEDSIVKVNLEEIDLEKLLEEISEDYIDIA
                     EFQEKRFVFNSKLKNKVIITDKNKLRQLILIFIDNAFKYTKLGDEIALELKEDIEDEV
                     TLLISDTGIGIKKEEIPLIFDRFFRSENVRNKDLEGSGIGLSIARMISLNLSIDINVT
                     SDVDIGTTFELSIPKKLK"
     gene            7062..7379
                     /gene="trxA"
                     /locus_tag="KRH23_002543"
     CDS             7062..7379
                     /gene="trxA"
                     /locus_tag="KRH23_002543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015035 - protein-disulfide reductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HHS5225821.1"
                     /translation="MAKVINTSEFRSSVEGSKGVVVVDFFATWCGPCNMLGPVFAELG
                     EEMKDKARFVKVDIDESLEIAQQFNVSTVPTMIIFKDGKPVETLIGFMPKNKIEMQVK
                     SYL"
     gene            7396..8274
                     /locus_tag="KRH23_002544"
     CDS             7396..8274
                     /locus_tag="KRH23_002544"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HHS5225822.1"
                     /translation="MRYDIAIIGSGPAGLSAAINAKIRNKTIIMFGNDNLSNKLVKAP
                     SIDNYLGFYDISGDELKDKFKSHIDSMDISIENKRINNIYAMGEYFTIMSGNDMYEAT
                     TVILATGVEYTRPIKGEEEFLGRGVGYCATCDAPLYRNKKVAVIGYNEESKEEANFLS
                     ELTSKTYFIPMYKKDNLMRSSDNLDDSIEVIHDRPVQIDGDKLVNKVSFKENHIEVDG
                     VFVIKDSTAPSALVPGIEIDGIHIKVDNNMKTSIDGCFAAGDCVGKPYSYIKAAGQGQ
                     IAALNAVYYLDKLKRA"
     gene            8544..8912
                     /locus_tag="KRH23_002545"
     CDS             8544..8912
                     /locus_tag="KRH23_002545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR/SmtB family transcription factor"
                     /protein_id="HHS5225823.1"
                     /translation="MENLVKIFKALSDETRLNILILVSKRNICQKGISKYLGISDSAV
                     SQHIKILKDVGIITGYKEGYYVLYHINKESFNICVDFINSMLSNSSESFIDVFDVNTI
                     HLGCSKECKSIKKCCKRREK"
     gene            8915..9286
                     /locus_tag="KRH23_002546"
     CDS             8915..9286
                     /locus_tag="KRH23_002546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NifB/NifX family molybdenum-iron cluster-binding
                     protein"
                     /protein_id="HHS5225824.1"
                     /translation="MKVCIPVEENKGLDSKPYGHFGSAPIFVVCDLESGEVKSLDNGD
                     LDHEHGKCQPLKALSGTAVDAVVVGGIGQGAIIKLNGMGIKVYRAEGDTISANLDLLK
                     NGKLVEFPSDHTCSHDGCGHH"
     gene            complement(9430..9885)
                     /locus_tag="KRH23_002547"
     CDS             complement(9430..9885)
                     /locus_tag="KRH23_002547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5225825.1"
                     /translation="MNINTVQGDSIEVLLRQLGATRISKVSSTLYFIKFDLGDGWEIS
                     YTYNINAKDQYFLQRIEPYPIGRGLFNDEYEIVSFISKDLKKFLNAKNSSNFKTFVEV
                     TRKVNSIIDNVEELFLNYNVDGDDLKTLNKELNDILNDIDYIEKHTKKI"
     gene            complement(9924..11189)
                     /locus_tag="KRH23_002548"
     CDS             complement(9924..11189)
                     /locus_tag="KRH23_002548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArsB/NhaD family transporter"
                     /protein_id="HHS5225826.1"
                     /translation="MEFQQIIAICIFLIVMAAIITEKVNRSVAAVGGALLMIIFNILT
                     LDEGLSHIDFNTIGVLVGMMLFVAVVKNSGLFEYIAIWTAKKAKGDPWKIMICFAIIT
                     AILSAVLDNVTTVLLIGPMTIVITQILGLNPVPFLITQILASNIGGTATLIGDPPNIM
                     IGSAANLSFMDFVINLGPAVIVILAITIICFRFIYGKELVVNERAKNAILKLDEKKSV
                     KDKPLLIKSLILIAFILFGFMFHSTIHIDSSVVALTGASIMLLIGKQDVDEIMAGIEW
                     STILFFMGLFVVVGGLVEVGIINKLAQALIGLTEGHLVFTMLLILWLSAIVSSFLDNI
                     PFVATLIPLILTMQAEGIDVMPLWWATSLGACLGGNGTLIGASANVVLAGIGNKHGHP
                     ISFKEYFKIGFPLMIISIIISTVYLIIKF"
     gene            11659..13110
                     /locus_tag="KRH23_002549"
     CDS             11659..13110
                     /locus_tag="KRH23_002549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005283 - amino acid:sodium symporter
                     activity [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine/glycine:cation symporter family protein"
                     /protein_id="HHS5225827.1"
                     /translation="MDFFNGILTSINNAVVYVNNYLWSYILIIMLVVIGIYFTIKTNF
                     VQFRYFIEMFRLLGDGTANKNAKKEGKISSFQAFCISTSSRVGTGNIAGIAIAVVAGG
                     PGAVFWMWLIALIGSASSFVESTLAQIYKVKDGQAFRGGPAYYMEQGLNKKWMGILFS
                     ILITICYGFVFNAVQANTVSLAFNNAFGISKMAMGIGLGILTAIVIFGGVHRVAKVSE
                     IIVPVFAGLYILVALAIVVMNITEIPSVIALIVESAFDFKGMAIGTFMGVVMTGVKRG
                     LFSNEAGMGSAPNAAATAHVTHPVKQGLIQSLGVFTDTIIICSCTAFMVLLYSGYSSS
                     GATGIELAQEALTHHIGPVGNIFIAVCIFLFAFSSIVGNYYYGESNMEFMSGSKTKLN
                     VFRVFVVGMVLFGSLTQVDVVWNLADLFMALMAIINLIAIALLGKYAFIALKDYTSQK
                     KSGIKDPVFIADEIEGLEKVSEWHRELSEEHLG"
     gene            complement(13330..13791)
                     /gene="ribH"
                     /locus_tag="KRH23_002550"
     CDS             complement(13330..13791)
                     /gene="ribH"
                     /locus_tag="KRH23_002550"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009349 - riboflavin synthase complex
                     [Evidence IEA];
                     GO_function: GO:0000906 - 6,7-dimethyl-8-ribityllumazine
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HHS5225828.1"
                     /translation="MIYEGKLIGKDLKIGIINSRFNEFITSKLLSGAEDCLLRHDVSP
                     ENIEIVWVPGAFEIPLVAQKMAKSGKYDAIICLGCVIRGATSHYDYVCSEVSKGIAKV
                     SLDSELPVIFGIVTTENIEQAIERAGTKAGNKGYDCAMNALEMANLFKSLN"
     gene            complement(13896..15089)
                     /locus_tag="KRH23_002551"
     CDS             complement(13896..15089)
                     /locus_tag="KRH23_002551"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003935 - GTP cyclohydrolase II activity
                     [Evidence IEA];
                     GO_function: GO:0008686 -
                     3,4-dihydroxy-2-butanone-4-phosphate synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HHS5225829.1"
                     /translation="MFNTIEEAIEDIKNGKMVIVVDDESRENEGDLLMAAEMATPESI
                     NFMATYGRGLICLPATEKKFKSLNIPLMVRENTDTFQTAFTVTIDGADTLTGISAYER
                     AETVKLFCDENSTSKDFKTPGHIFPLIAKTGGVLVRDGHTEASVDLARLAGFKEIGLI
                     CEIMKDDGTMARVDDLMIFKEKHNLKIITIKDLIEYRKINETTIEKVSSAFLPTKYGN
                     FEIIGYRDAYSNEEHIALTYGNINIENTLVRLHSECLTGDVFHSLKCDCGLQLESSMK
                     KIVENGSGVLIYMKQEGRGIGLLNKIKAYKLQEEGYDTVEANLMLGFEEDMRDFYMAA
                     QILKNLNIKSINLLSNNPDKINQLEKYGIKIENRIPINEEINDFNKLYLKTKKDKMGH
                     LLDII"
     gene            complement(15112..15777)
                     /locus_tag="KRH23_002552"
     CDS             complement(15112..15777)
                     /locus_tag="KRH23_002552"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HHS5225830.1"
                     /translation="MFTGIVEEVGILRKITANGKSGKVTILSNKILDGTNLGDSIAVN
                     GVCLTVSNLGKNEFTADVMMETIRSTNLGLLNANDKVNLERAMSLSSRFGGHIVTGHV
                     DGKGTICKFEKDENAVLVSIRPDKKLLSSMILKGSVAIDGVSLTISYLDDEIFKVSII
                     PHTKINTILLTKNVGDFVNLESDVIGKYVNNFMANNYKELNSNSSNHKSNIDKDFLFK
                     NGF"
     gene            complement(15811..16923)
                     /gene="ribD"
                     /locus_tag="KRH23_002553"
     CDS             complement(15811..16923)
                     /gene="ribD"
                     /locus_tag="KRH23_002553"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008703 -
                     5-amino-6-(5-phosphoribosylamino)uracil reductase activity
                     [Evidence IEA];
                     GO_function: GO:0008835 -
                     diaminohydroxyphosphoribosylaminopyrimidine deaminase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HHS5225831.1"
                     /translation="MNFVNQKEKDIYYMKKAIELAKNGEGFVNPNPLVGCVIVKDSNI
                     IGKGYHEKFGSNHAEVNAINSAKQSLKDSTLYVNLEPCSHYGKTPPCVDKIIQNKIKR
                     VVISTLDPNPLVCGNGVKKLKDNNIDVTVGILEDEARDLNEAFFYHIKNKRPLCIVKS
                     AVSLDGKIATKSLESKWISNESSRYLTHKYRNKYQSIMVGINTVLNDNPLLTCRLNQE
                     KVSHPTRIVIDTHLKLPLNSNLVKDKTSKTIVFTCCKESIKLSMLKENNVETIISPSK
                     NNLVDLEFVMYKLGELNIDSVLVEGGATLNDSLFRNKLVDKVKLFLSPKIIGGKDAPT
                     FVSGEGINHLSDSTQLTINNVTLIDGDILIESDVLN"
     regulatory      complement(17055..17176)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            17365..19848
                     /gene="recQ"
                     /locus_tag="KRH23_002554"
     CDS             17365..19848
                     /gene="recQ"
                     /locus_tag="KRH23_002554"
                     /EC_number="5.6.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0009432 - SOS response [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase RecQ"
                     /protein_id="HHS5225832.1"
                     /translation="MNKKLLEILSKYYGYTSFRKGQESIINSILSEKDVLAIMPTGGG
                     KSICYQIPALILDGMTIVISPLISLMKDQVDALKTMGISAAFINSSLSSKEFNEILNN
                     IRKNNYKILYIAPERLDAQEFIELINNNNVSQVAIDEAHCVSQWGHDFRLSYRRISDF
                     IKNLPKRPIVTAFTATASEEVRTDIINLLCLENPDYYITGFDRENLSINIVKSSSKNK
                     YILDYIQNHKNESGIIYVATRKEVENIYNGLSKRNVSVSKYHAGLSKNERSKNQEDFI
                     NDNVDIMVATNAFGMGIDKPNIRWVIHYNMPQSIENYYQEIGRAGRDGEKSECVLLFS
                     PGDVHIQKYLIDIGVENPERKLFQHKKLQYMIDLVYSNSCYRKTILSYFGENYIDNCN
                     NCSNCLVEGEIVDKTIDAQKVISCVARMKRSYGVTTIVDVLRGSKNKKILQLGLNTLS
                     TYNIMRDYSSEDLKNFINTLVSHGFLDLVETLGNGNRGSFPTIRLNEMSMKVLKGEVK
                     VEFKEIVMTKSLEVEDELYNALRELRHSIASEERIAPYMVFGDGTLRAMSSSYPINKE
                     EMLDISGVGEIKYQKYGRDFEAVIKEYVEKNNINKKIDEKNVDSKNVNSDFLEVNTDK
                     VLYEKLLVIREEYATKEKLPAYMILANKALKEISGRYPLDEEQLKDISGIGGVKFEKY
                     GASILAEVNKYVKENNINVIWEKKGKRKLILDGESRKNNEIALDLLNQGKDIQSISQE
                     IEVSLSTIIGYVHDYVKDGHSISFELGLENFYNEDKKKMILEVCEKVGYDNLNNIKRK
                     LPDSIKYENIRAVILDSYLENLKNNIIAE"
     regulatory      19937..20048
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            20190..21491
                     /gene="thiC"
                     /locus_tag="KRH23_002555"
     CDS             20190..21491
                     /gene="thiC"
                     /locus_tag="KRH23_002555"
                     /EC_number="4.1.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomethylpyrimidine synthase ThiC"
                     /protein_id="HHS5225833.1"
                     /translation="MNYTTQMDAARKGIITKEMEIVSQKEQVDVNELRELIANGQVVI
                     PANKNHKSLSAEGVGKNLRTKINVNLGISRDCKDIEKELEKVRVAIDMKAEAIMDLSN
                     YGKTREFREKVVEMSPAMIGSVPMYDAVGYLEKELKDITEEEFLNVIRQHAIDGVDFI
                     TIHAGLTRSVCQKIKNHERLTHIVSRGGSLLFAWMELNNKENPIYTNFDKILDICEEY
                     DVTLSLGDACRPGCIKDSTDGVQIQELVVLGELTKRAWERNVQVMIEGPGHMAIDEIE
                     ANVVLEKRLCHGAPFYVLGPLVTDIAPGYDHITSAIGGALACAKGVDFLCYVTPAEHL
                     RLPNLDDMKEGIIAAKIAAHAGDIAKNVKGAREWDNKMSKARADLDWCEMFRLAIDPE
                     KAKRYRDESTPTHEDSCTMCGKMCSMRTVKKILNNEELNLI"
     gene            21545..21739
                     /gene="thiS"
                     /locus_tag="KRH23_002556"
     CDS             21545..21739
                     /gene="thiS"
                     /locus_tag="KRH23_002556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfur carrier protein ThiS"
                     /protein_id="HHS5225834.1"
                     /translation="MKVNGKEIEFEKDLTVIDLLNKYNLKSDRVVVEVNLEIIEESNY
                     NTYVLKDEDIVELISFIGGG"
     gene            21732..22535
                     /gene="thiF"
                     /locus_tag="KRH23_002557"
     CDS             21732..22535
                     /gene="thiF"
                     /locus_tag="KRH23_002557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine biosynthesis protein ThiF"
                     /protein_id="HHS5225835.1"
                     /translation="MVKIKIFVNELLTDVEENTTAYKVRDSYNNKCDVLVLNGYPIKT
                     DMPLCENDKLTLIQKGVKPSLDELESLLIARHTPNIHNKLKKGKVAILGLGGLGSNIA
                     ISLARIGVGELLLIDYDVVEPSNLNRQQYFIDDIGKLKTDAMIENIKKINPFIKLNKR
                     DIFLNKNNMDTIKDSDLIIEAFDDASCKAQVCNYVLINLKDKYLIASSGMAGYYDSNI
                     ITTKKIKDRFYICGDFVNEAKFGEGLMAPRVAICANHMANLATQILIDM"
     gene            22598..23368
                     /locus_tag="KRH23_002558"
     CDS             22598..23368
                     /locus_tag="KRH23_002558"
                     /EC_number="2.8.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018592874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1990107 - thiazole synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiazole synthase"
                     /protein_id="HHS5225836.1"
                     /translation="MDKLVLGGHEFNSRLLVGTGKYGSNNILPEVIKESGSEIITMAL
                     RRVDLDNKQENILTYIPKEMTILPNTSGATNAEEAVRIARISRKMGCGDFIKIEVISD
                     TRYLLPDNEETIKATKILADEGFIVLPYMTPDLYAGRRLIEANAAAVMPLGAPIGSNR
                     GLQMKEMIRIMIDELDIPIIVDAGIGKPSQAMEAMEMGADAVLVNTAIASAGDPVQMA
                     RAFKLAVEGGREAYIAKTGNVSEFANASSPLTGFLGNL"
     gene            23385..24488
                     /gene="thiH"
                     /locus_tag="KRH23_002559"
     CDS             23385..24488
                     /gene="thiH"
                     /locus_tag="KRH23_002559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0016829 - lyase activity [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-iminoacetate synthase ThiH"
                     /protein_id="HHS5225837.1"
                     /translation="MSFYDVIEKYRDFDFDGYLNNVTDNDVLRSLSKDKLEDFDILNL
                     LSKTAVKHLEDMAQKAHKLSVQYFGKTVCLYTPMYIANYCVNQCVYCSYNIKSGIKRK
                     KLTMDEIREEGEAISKEGFKHLLVLTGESSFHSSVEYIGEAIEILREKFPSIGIEVYP
                     MEVEEYKYIVDKGVEGLTVYQETYDEEIYKRVHIKGPKSNYKFRLDAPERGAKAGMRT
                     LSIGALLGLNDFRKETFFTILHGKYLKTKYPHIELSYSTPRMRPFKGCFEELVDISDT
                     DLVQAMVCMRLFDPHAAINISTRENLEMRSHIIPLGVTKLSAGVSTDVGGHSQDEHDT
                     AQFKINDESTVKDVEKMLNSIGYQHVFKDWERF"
     gene            24489..25178
                     /locus_tag="KRH23_002560"
     CDS             24489..25178
                     /locus_tag="KRH23_002560"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004789 - thiamine-phosphate
                     diphosphorylase activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009229 - thiamine diphosphate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HHS5225838.1"
                     /translation="MYLITNRKLCSEERYLEVIKESILSGVENIIIREKDLEYQELKK
                     LYMKIKTKINCIDFQEQISDESLKTNINQKECRNKFKVNFIINSNIEFFEKVDCQGIH
                     LPFKLFLNLIENKYNFNENKILGLSLHKVEEVDYLEKLIRNQNIKIDYITLSHIYETK
                     CKEGLNPKGIELLKEAKKITDIKIIALGGILPSNVKETLKYCDDFAIMSTIMRSKDIK
                     KTISNYNEKLN"
     gene            25366..26760
                     /locus_tag="KRH23_002561"
     CDS             25366..26760
                     /locus_tag="KRH23_002561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HHS5225839.1"
                     /translation="MTDSKKKRFIIPHTFTIIFLLIVLMAILTWIVPSGEFSREDVEG
                     RMVVVPGTYQSVESNPQGFADVFKAPIEGFIDSAEVVGFVLIVGGAFGIVNRTGAIEA
                     GIASVISKFKGKELLIIPISMILFGLGGTTFGMAEETLPFYMIFVPLMTSLGYDSLTA
                     IAIVFIGAAAGAAASTINPFSVGIAQALAQLAPGSGVTYRVVIFIAYILISIAFVMYY
                     AKKVKENPESSIVYEIDKNNKSILNQTSTEIKEFTFKEVSVLAIFGIGMAIMIWGVLS
                     QGWYIPEISMCFAAIGVLSGLVGRLSQIEISESFIDGAKDLASAALAIALARGIVIIA
                     QNGFIIDTILNSAAAFLGGLPKVIFVYLSFFLEAALAFLIPSSSGLASLTVPVLAPLG
                     DLVNISAQVIVTAYQFGVGLTNFITPTSGVLMGALAVAHIPFSKWVRFIMPILLILTA
                     VSLVFLTIGIYIGF"
     gene            27277..28644
                     /locus_tag="KRH23_002562"
     CDS             27277..28644
                     /locus_tag="KRH23_002562"
                     /EC_number="2.7.6.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008728 - GTP diphosphokinase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0015969 - guanosine tetraphosphate
                     metabolic process [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase"
                     /protein_id="HHS5225840.1"
                     /translation="MGLKEFDFIEESIDMLRTMSPTLETISDEIEEYFENILDEKNQE
                     YINVTSRIKSESSLREKIIRNRYLKKYGEASNLIHNVSDLIGLRIECRFIEDENKIYR
                     LLRRYFNKTDDKINYYNKENKNIKLKLSERQPNKQKNGFEIYKIDGVFAYLDREVKFE
                     LQIKSLVNVFWSEIEHKIIYKNNTYLLADKFIKDMMDSIKNNLTMIDNQLLSIYKNFH
                     SGKSFNMKVSKKEIEKLFAKLVYDAFSEKMNKSIGFVVDFKKPCETILNYSFNKQDIS
                     DEVLGNFMLDEFARLNEIVNKDIDFNEQIEFEREPTFDDKFCKDLGNHFRSRLNTEFP
                     WNLFFRILFEIEPYNNTKDFENFVEFIKENVLLEENREQLLCQFEEDSKLIIEDIYDC
                     IFNSISEIDSVEILYNYNLEKINFTSSEIINCICREYECYGEYLEEKEKLMNTFKEKI
                     IQIFE"
     gene            28669..29277
                     /locus_tag="KRH23_002563"
     CDS             28669..29277
                     /locus_tag="KRH23_002563"
                     /EC_number="2.7.7.77"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0061603 - molybdenum cofactor
                     guanylyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum cofactor guanylyltransferase"
                     /protein_id="HHS5225841.1"
                     /translation="MRHFSNIYELSKIILEEAICIEKTGVILAGGRNSRMGRDKAFLE
                     LHDKLFIEIAIEAFKNFDELIIISNNEELYSKYDIKVYNDIVKDVGPIGGIYTALEYA
                     KYDIVTIACDMPYLNNQIVERIANKMDDKSVISVTNGKLQPLCSGYKKSIINKVSLCI
                     RENDLKLRSFIDKIDKSYIYFDEEDLFLNVNTVDEYKKLTKV"
     gene            29325..29696
                     /locus_tag="KRH23_002564"
     CDS             29325..29696
                     /locus_tag="KRH23_002564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0120225 - coenzyme A binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HHS5225842.1"
                     /translation="MNLLKCDSWAVILNNSDKESKAYKILDELKRNMYKVVAIDEEKK
                     PIEGIDVYECLKDVPHNIDVVAIIDKQSKMDVILEEVELLDIQNMWFEKGSFSEMMIK
                     KTKDLKLNIEYNLSLYDELTR"
     gene            29875..30213
                     /locus_tag="KRH23_002565"
     CDS             29875..30213
                     /locus_tag="KRH23_002565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HHS5225843.1"
                     /translation="MLIVTTEKVEGKKISKVLGLVRGSTIRAKHVGKDIGASFKNLVG
                     GELTGYNEMLTEARQIAIGRMVEDAEAKGANAVIAFRLSSASVMQGAAEMLAYGTAVV
                     LEDDNSILEK"
     gene            30680..31183
                     /locus_tag="KRH23_002566"
     CDS             30680..31183
                     /locus_tag="KRH23_002566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030151 - molybdenum ion binding [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006777 - Mo-molybdopterin cofactor
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MogA/MoaB family molybdenum cofactor
                     biosynthesis protein"
                     /protein_id="HHS5225844.1"
                     /translation="MFNVAIITLSDKGYEGKREDITGKKLTEFVENTGAYKVTEYVLI
                     KDDKEMLKENIIRLCNSNKIDLILTNGGTGFSKRDITPEATKEVLEKEIPGLSEYMRM
                     KSTEITKKAILSRGVSGIRNNSIIINLPGSPKGAVENLSFIIDVLDHGIEVLRGEATE
                     CATKKSE"
     gene            31230..32189
                     /gene="moaA"
                     /locus_tag="KRH23_002567"
     CDS             31230..32189
                     /gene="moaA"
                     /locus_tag="KRH23_002567"
                     /EC_number="4.1.99.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0006777 - Mo-molybdopterin cofactor
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP 3',8-cyclase MoaA"
                     /protein_id="HHS5225845.1"
                     /translation="MIDKYGRKIDYLRISLTDKCNLRCVYCMPPDVKFDKNYINENLS
                     FEDYKFIIKAMAEQGITKIRFTGGEPLLYPKLNELIKFTKEECGINNIGMTTNAIGLS
                     DRIFELEKCGLNKVNISLDSLKEYKYKSVTRGGNLKDVLKSIESCLNLGIKVKLNCVA
                     ISGFNDDELKDFMFLTVKSPIDVRFIELMPLGEANRVYKKGYFNVKEMIEKIYGLYKV
                     KNDEKSTAEYYMFKGAKGRIGIITPLSCSFCNTCNRIRLTSSGAIKLCLHSKEEIDIK
                     PFLHKPLLFRESMKDIIKQKPEKHHLIENKCSDTNRRMYEIGG"
     gene            32193..32663
                     /gene="moaC"
                     /locus_tag="KRH23_002568"
     CDS             32193..32663
                     /gene="moaC"
                     /locus_tag="KRH23_002568"
                     /EC_number="4.6.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0061799 - cyclic pyranopterin
                     monophosphate synthase activity [Evidence IEA];
                     GO_process: GO:0006777 - Mo-molybdopterin cofactor
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic pyranopterin monophosphate synthase MoaC"
                     /protein_id="HHS5225846.1"
                     /translation="MLTHINEKGYAKMVDISEKDDTKRTAVATATITLSKEALEKVKN
                     GQIKKGDVLSVAQVAGIMGAKNTSSNIPMCHQIKLVGCDLEFDVDDSMSAIKIYATCK
                     SLGKTGVEMEALNACSLAALTIYDMCKAVDKKMVISNIHLVEKTGGKSGDFKFE"
     gene            32699..>33126
                     /locus_tag="KRH23_002569"
     CDS             32699..>33126
                     /locus_tag="KRH23_002569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030151 - molybdenum ion binding [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MOSC domain-containing protein"
                     /protein_id="HHS5225847.1"
                     /translation="MAKVVSINISEKKGVIKVPVQCAELKINHGIVGDAHAGNWHRQI
                     SLLGKESIDKMKMKGFDQLKYGDFAENVTTEGIEVFSLPVGTKLRIGQCEVEVTQIGK
                     KCHNGCEIKKLTGDCVMPREGIFVKVLKEGIINVNDSIDV"
BASE COUNT        12954 a         3547 c         5651 g        10974 t
ORIGIN      
        1 tttaagatat tattgtataa taataatcgg tttaaatgcg ccacatctta ttaaagttgg
       61 ttcataattc taaataaact ttaataagat acattaaaat ataataaatt cttttatgct
      121 ataaaattta ttttatagct attaaatcag atgtttaaaa attttttaac agtctatagt
      181 ttttaagagt ctatagtaag tagcctaaaa atatgatttt acatctgtac ttgttcgaga
      241 actccaagta taaaaaacta aggaattata tagtggcagt atataattaa tacccttaga
      301 cacacctttt tgaaagtgga aaaaagatgt gtagttctcc tcgaccacaa atcaaggagg
      361 ataaaaaatg gaaaagagaa aagtaataat tgattgtgac ccaggaattg atgattcttt
      421 ggcaattctt ctggctttaa actcaccaga gctagaagta attggaatta ccacatgttg
      481 tggaaatgtt ccagcaaata taggtgcaga aaatgcacta aaaacacttc aaatgtgttc
      541 ttcactaaat attccagtat atataggaga agaagcacca ctaaaaagaa aacttgtaac
      601 agctcaagat acacatggag aagatggtat tggagaaaac ttttatcaaa aggttgtagg
      661 agctaaagca aaaaatggag cagtggattt tataataaat actttacata atcatgaaaa
      721 agtatcaata atagcacttg caccacttac aaatatagct aaagcactta ttaaagataa
      781 gaaagcattt gaaaatctcg atgagtttgt gtctatggga ggagcattta ggattcatgg
      841 aaattgctct ccagtagcag agtttaatta ttgggtagac ccacatggag cagattatgt
      901 ttacaagaat ttatctaaaa aaatccacat ggtaggttta gatgtaacta gaaaaattgt
      961 acttactcct aatattattg agtttataaa tagacttgat aagaagatgg caaagtatat
     1021 aactgaaata actagatttt atattgattt ccattgggaa caggagggaa taattggctg
     1081 tgtgataaat gaccctctag cagtagcgta ctttatagat agaagtatat gtaaaggatt
     1141 tgaatcatat gtagaagttg tagaagatgg aatagctatg ggtcagtcta tagtggattc
     1201 tttcaatttc tataaaaaaa atcctaatgc aattgttcta aatgaagttg atgagaagaa
     1261 atttatgtac atgtttttaa agaggctttt taaaggttat gaagacatta tagactctgt
     1321 ggaaggagtg atatagtgtg aaaagaaaaa tatgtgtaaa aactattaca cttatagctt
     1381 ttggtatttc tataaatata ataggtgctt ttatagctat gggattaaga ttacctgtat
     1441 acttagattc aataggaact ataatgatag cttcactttt aggacctaaa tacgctgttg
     1501 ttacaggtgt gtttggaagt ttaataagtg gaattacgtt tgatgtgtat tctctctatt
     1561 ttgcaccagt tcaaatatca accggattac ttgctggaat agcatttaaa aagaattttt
     1621 taaggggttt aaaaactcca ctaggagtac ttttatttgc cattccaaca tctataataa
     1681 gttcaataat ttcagcattt ttatttggag gtatgacctc ttcaggttca tcatatatag
     1741 tgcaaatctt gaaagtgtta ggactggggg atgtttttag tgtgtttgta acccaagtat
     1801 ttactgatta tggagataag ctgttagcag ttgttttagt gaatttagga ttaaatgcag
     1861 ttccaaaaac tttaaaggta tcattgactg gaggaaaata gatagaaaat ggatagatat
     1921 agtgagataa caaataaaaa tcaaagagaa attgttctgc ttaaaggatt tccttgtata
     1981 tggggaaagt gttctttttg tgattatata gatgataatt ctaatttaga agaagagatg
     2041 aataaattaa atctaaaggt tttaaaaaac gtaactggga aatatggagt tcttgaagtc
     2101 ataaattctg gaagctgttt tgaattacct aaggatactt tagaaaaaat aaagtgtatt
     2161 ataaaagaga agaatataaa aaaattattt ttagaaagtc attggtctta caaaaatagg
     2221 cttaaggaaa tgagagagta ttttgaaatt cctgtggtat ttaaaattgg agttgaaacc
     2281 tttgacaatg attttagaaa taatatttta aataaaaatg caaattttaa gactccacaa
     2341 gatgtaaaag aatattttga ttcaccttgt attatggttg gaataaaagg acaaacaaaa
     2401 gagatgatag ataaagatat agagattatc ctaaatactt ttgaaaaagc gacagtgaat
     2461 gtttttataa ataattcttc tagtataaaa agagatgaag agttagtgaa atggtttgtt
     2521 agtaagtata aattcttgga tgaaaatcca aatatagaag ttttatacaa taatacagac
     2581 tttggtgtag gagattagca ttaatttagt ttaaatttaa aattgaaaag tttcttatgt
     2641 ttttgaaaaa gcttctaata gttagaagct ttttttgtag agttttatgt tacaataaga
     2701 aaaaaggaat taaggagcaa ttaaatgatg tttgataggg gaaaatggaa taaattggat
     2761 tataatgaac ttttagaata tatgatgtct atacaagata taaaatatag agattttaat
     2821 aaaaagctta tacctggaac agaaaatata ataggtatta gagttcctaa tttaagaaaa
     2881 ttatcaaaag aaataagcca agggaattgg aaggaatttt tagaagtagc agaggataca
     2941 tactatgaag aagttaggct acaaggtatg gtaattggca atataaatag taattttgaa
     3001 gaaactttat actatgtaaa aagatttata cctaaaatcg ataattggtc agtttgcgat
     3061 ggattttgtt ctgatttaaa gtctatgaaa aaatataaag aaaatatgta tgatatactt
     3121 aaaaaatatg tttattcaaa gaatccatgg gaaattagat ttgcattagt tatgttttta
     3181 atatattatg ttgatgataa acatattaaa gaaatatttg aatactgtaa taatatacaa
     3241 agtgaagaat attatgttaa aatgggtatg gcatggttgc tatcaatttg ttttattaaa
     3301 tgtgaagagg aaacttttct ctatataaaa aataataatt tagatgattt cacttataat
     3361 aaaatgctac aaaaaataat tgaatcaaat agagtagatt tagaaaagaa gaatataata
     3421 agaagtatga aaagaaagac aagaagatgt tgacggagga atattaatga ataacaatga
     3481 agacagaatt gacaaatttt tagaacttca aagcaaagga tttaaatttg cagagatagc
     3541 tcaaaatcta aagattagtc aaagtacttt aagaactttt ttaaataaaa aaggatataa
     3601 gtcagaaaaa ggtaaataca tattaaaaga cgaattaaat tataataaaa gtttggataa
     3661 tagaaacttg gaagaagaga aagctaagga gtatgaaaaa agtaaaaaga atactataag
     3721 taatagaaaa aaagtaagca ccaaaaaaaa gatctctaat gaaaaggctt taagtaaaag
     3781 tgttgaacaa attgagttta atgatacagg tttaaaaaat gcaaagccaa aacaaaatgt
     3841 taagcctaag aaagatagaa aaataaatat aactcaagaa gatttagata agctttgtga
     3901 agtatatgat tggtatttag aagtaaaaga ttacaatata aagcctaaaa aagtatctaa
     3961 taaaaaagat gtacatatag atgatgaaca catagatgaa ttaaaaacaa caagaatacg
     4021 tatagataaa gaagtatgga atgattttga aagattatgt agtaattcga attttgaaaa
     4081 acatcaaata cttacacagg cattgaaaga atttatgaaa aagtataaaa atctactata
     4141 aaatactact atatgaggtg cttaatatga atgaaatagt aaaaaaatca atttctctaa
     4201 tgattatatt aacaatattt atttttatgt tgacagcatg tgaaaaagat gaacagcctg
     4261 attcagttga tattcaaaca gaagataaaa atgagataaa aatagatgag ggaaatgcaa
     4321 aagtattgaa tataggaaaa tcagaaatta taaatataga tgaaggtgat aaagtagata
     4381 catcaacaaa ggtagaaaat aattcaacat ttaatatatc caatgttgaa ttgatatata
     4441 atgaatatga tgagaataaa aaaattatat cttcggatag taaggctttg ttggacatga
     4501 ctttaatgcc tgggaaagtt gcttacatag aatgtgggca taaaactttt gtaaagggtg
     4561 tagaagttta tgcatatgaa tatgaggcag agggtaagat tgtgtatgtt aatttaaaag
     4621 aaaatactat taatataaga aataataata ttaagctaga aaatagtagt cagtatgagg
     4681 tgctatctac atcagaactt aaaaaagtaa atgaatcaaa tgagggaatt acgtatcaag
     4741 taaaagtaaa aaattcatca tcaaaagatt taggaaatat tattcttaag acagcagaag
     4801 ttaatgaaaa tggagaatat ttaacagtaa atcgtgtgcc atcatataag attttaaagc
     4861 cttcagaaga gacagatata gatatattgt gttcaacaaa ggcaaaaagt gttgaaatag
     4921 tgggatatac gtatgatgat ataaaagaaa aagccaatgt ggatattgac ttaaaatctc
     4981 ataaagttaa gatagacaaa taaaggtagg ggatacttat gaaggtttta atagttgaag
     5041 ataataagat acttttagaa agtgtagtag aagaacttag caagcatttt gaaactgaaa
     5101 agtgtgaaga tggagaagaa gctttatact tagtaaatca aaatatatat gatttagtca
     5161 ttttagactt aatgcttcct aatataaatg gatttgatat cctaaagaaa atgagagtta
     5221 ataatataga tacacctgta cttatattga cagcaaaaga aacattagat gacaaagtag
     5281 aagcatttac tataggagct aatgattatt tgacaaaacc tttttatatg gaagagttag
     5341 tagctagggt atacgctata ttaaggacta atggaaagat aaaagaaaga aacggattag
     5401 aatttaaagc tttatattta gatacactag aaaaaagagt gtatattgaa aaagaagaaa
     5461 taaaacttca aaacaaacag tttaacttgc ttgagtattt tgtattaaat aaaggttcaa
     5521 ttttattaaa agagcagatt tatgatagaa tatggggaat tgattcagat gcgactattg
     5581 aaatagtgga agtatatgta agtaatctaa gaaaaaagct aagtaaatat ggatatgata
     5641 aatatattaa aactaaacgt aaggtaggat atatattcga tgataaataa gaatgtattt
     5701 accagtacta aaaatcattt aataaaaatg tatattattg tagtaggtag ttttttaata
     5761 atcttttcta tatttatata ctcatatttt aggggactta catatagtgg aattgatagt
     5821 gagataaatg atgaacttga atatatagtc tctcaattta aaagaacttc atttttgaac
     5881 ccaataagac tgaaagatcc taaagatatg gtgtatgtat atgaagatgg aaggataagt
     5941 tactatactc aaaatgaata ttttgatgag ttacttccag atagaagact agataaaaaa
     6001 aattcgtttt ttaaatacac agaaaatgga tatactttta gagaattaaa tgtagatgta
     6061 ggtagatacc aaatacagat aattagaaat atagattctg agatgaattc tttaagacag
     6121 cttacatctg ttcttataat tggaatatta atttctgtaa taattactta ctttgtggct
     6181 gtatatctca ctagaaaagc tttaattcca atagaaacag catggaaaaa tcaagctaag
     6241 tttatacaag atgcttctca tgaattaaga acaccaataa caatagtttc atcaaaatta
     6301 gaaagtatgt taaaatcccc agaaagtaca gtaaatgatg aagttgaaac aatagctact
     6361 gcaatgaagg aaactagaag acttaaaaaa atgataactg atttattgtc tcttactaaa
     6421 gaggactcta ttgttaaagt taatttagaa gaaatagact tagaaaagtt attggaagaa
     6481 atatcagaag actatattga cattgctgag tttcaggaaa aaagattcgt gtttaattct
     6541 aaactgaaga ataaagttat aataacagat aaaaataaat taagacagct tatattaatt
     6601 ttcattgata atgcctttaa gtatacaaaa ttgggtgatg agatagcatt agaattgaaa
     6661 gaagatatag aggatgaggt aactttactt ataagtgaca ctggtatagg cataaaaaaa
     6721 gaagagatac ctcttatatt tgatagattt tttagaagtg aaaatgtaag aaataaagat
     6781 ttagaaggtt ctggaatagg actttcaata gctcgcatga ttagtttaaa cttatctatt
     6841 gatataaatg taacttctga tgtagatatt ggaactacat ttgaattgtc aatacccaaa
     6901 aagttaaaat aataaaaata taaaaaattg tttttagaaa tgaagaatgg gtatactaat
     6961 tagtataaaa tataaaaaga ccttataaaa gtaaatttat atttataaat ttcatagtat
     7021 aattatatag ggataataaa gtttaatagg aggatttaaa aatggcaaaa gttataaata
     7081 catctgaatt tagaagtagt gttgaaggta gtaagggagt agttgtagtt gatttctttg
     7141 caacttggtg tggaccttgt aacatgttgg gacctgtatt tgcagaatta ggtgaagaga
     7201 tgaaggataa agctagattt gtaaaagttg atatagatga gagtttagaa atagctcaac
     7261 aattcaatgt atctacagta ccaactatga ttatatttaa agatggaaaa ccagtagaaa
     7321 ctttaattgg attcatgcca aagaacaaaa ttgaaatgca agtaaaatca tatttataaa
     7381 aaatgggtga gtattatgag atatgatata gctataatcg gcagtggtcc agctggattg
     7441 tctgctgcta taaatgcaaa aataagaaat aaaacaatta tcatgtttgg taatgataat
     7501 ttaagtaata agcttgttaa agctccttca atagataatt atttaggttt ttatgatata
     7561 agtggtgatg aattaaaaga caagtttaaa tcacatatag atagtatgga tatttcaatt
     7621 gaaaataaaa gaataaataa tatttatgct atgggagaat actttacaat aatgtctgga
     7681 aatgatatgt atgaagctac tactgtaatc cttgcaactg gggtagagta tactagacca
     7741 atcaagggtg aagaagaatt tctaggaaga ggtgtgggct actgtgctac atgtgatgca
     7801 ccactttata gaaataaaaa ggtagcagtt ataggatata atgaagaatc taaagaagaa
     7861 gcaaattttt taagtgaact cacttcaaag acttatttta tacctatgta caaaaaagat
     7921 aatcttatga gaagttcaga taacctagat gattctattg aagttataca tgacagacca
     7981 gtacagatag atggagataa acttgtaaac aaagtatctt ttaaagaaaa ccacattgaa
     8041 gttgatggag tattcgttat aaaagatagt acggctccaa gtgcattggt tcctggaata
     8101 gagattgatg gcattcatat taaagttgac aataatatga agactagtat agatggatgc
     8161 tttgctgctg gagattgtgt tggaaaacca tattcttata taaaagcagc tggtcaaggg
     8221 caaatagcag ctttaaatgc tgtttactat ttagataaat taaagagggc ttaatattta
     8281 tattgattaa ctttttaaag atatttataa aaaactgtct tgaaataatt ttattatttc
     8341 aagacagttt tttattttta agttattaat aaaagtattt taaaatctat atgtaattac
     8401 ttttattaat aaaactcaaa gttatattag taaaaattgg aattatttat aatatactcc
     8461 aaaatttaaa aataatggtt gaaaaatcta attaagagta ctataattta attaagtaat
     8521 tacttaatca aaatgaggta cttatggaaa acttggttaa aatatttaaa gcattgagtg
     8581 atgaaactag acttaacata cttatattag tatccaagag aaatatatgt caaaagggga
     8641 tttctaaata tctagggatt tcagattctg ctgtttcaca acatataaaa atattaaaag
     8701 atgttgggat aataacagga tataaagaag gatactatgt tttatatcat attaataaag
     8761 aatcatttaa tatatgtgta gattttataa attctatgtt aagtaattct agtgaaagct
     8821 ttatagatgt atttgatgta aatacaatac atctaggatg cagtaaagaa tgtaaatcta
     8881 taaaaaaatg ttgtaagaga agggagaaat aataatgaaa gtatgtatac cagtagagga
     8941 gaataaagga ttggatagta aaccatatgg acattttggt tctgctccaa tttttgttgt
     9001 gtgtgattta gaaagtggag aagttaaatc tttagataat ggagatttag atcatgaaca
     9061 tggaaaatgt caaccattaa aagcattgtc agggacagct gtagatgcag tagttgttgg
     9121 tggaatagga caaggagcta taattaaatt aaatggaatg ggaataaaag tttacagagc
     9181 agaaggtgat actataagtg ctaatttaga cttacttaaa aatggaaaat tagtagagtt
     9241 tccatcagac catacttgct cacatgacgg atgtggacat cattaaaaaa aacagctgat
     9301 gaaatatata cttcatcagc tattttttct tttaataaat acgattttat tcttttaaaa
     9361 ccaaaattta gatttttatg ttttttgtag tatccttaat aatatttcaa gtttacaagt
     9421 ttactacttt tagatttttt ttgtatgttt ttctatatag tcaatatcat ttaatatgtc
     9481 attgagttct ttattaagtg tttttaaatc atcaccatct acattgtagt ttaaaaatag
     9541 ttcctctaca ttatcaatga tagaattgac ttttctagta acttcaacaa atgtcttaaa
     9601 gttactacta tttttagcat ttagaaattt ttttaaatcc tttgatataa atgatactat
     9661 ttcatattca tcattaaata gacctctacc aataggatat ggttcaattc tctgtaaaaa
     9721 atattggtct ttagcattaa tattataagt ataagatatt tcccaaccgt ctcctaaatc
     9781 aaacttgata aaatataatg tactacttac ttttgatatt cttgtggcac caagctgtct
     9841 taaaagaact tcaatcgaat caccttgaac agtattaata ttcatatata cacatcccct
     9901 ttagtattat tatactatat tttttaaaat tttataatta aataaacagt agatataata
     9961 atagatataa tcataagtgg aaaacctatt ttgaaatact ccttaaaaga gataggatga
    10021 ccgtgtttat tacctatacc tgctagtaca acattagcag atgctcctat tagtgttcca
    10081 tttcctccaa gacaagctcc aagagatgtt gcccaccata gtggcattac atcaatacct
    10141 tcagcttgca tagtcaaaat aagaggaatt agtgttgcaa caaatggaat attatctaag
    10201 aaagaagaga ctatagctga caaccataat atcaacaaca ttgtaaatac aagatgtcct
    10261 tctgtaagtc caatcaatgc ttgagccaat ttgtttatta tcccaacttc tactaatcca
    10321 ccaactacta caaataatcc cataaagaat aaaattgtag accattcaat acctgccata
    10381 atttcatcta catcttgttt tcctattaaa agcattatag atgctcctgt cagtgctaca
    10441 acagaagaat ctatgtggat tgtactgtga aacataaaac caaaaagtat gaatgctatt
    10501 aatataaggc tttttataag tagaggttta tctttaacag attttttttc atctagtttt
    10561 aatattgcat ttttagctct ttcattcaca acaagttctt ttccataaat aaatctaaag
    10621 catattatag ttatagcaag tattactata acagcaggac ctaaatttat tacaaaatcc
    10681 ataaaactaa gattggcagc actaccaatc ataatatttg gagggtctcc tataagagta
    10741 gctgttcctc ctatatttga agctaaaatc tgtgttatta aaaatggaac tggattaagt
    10801 cctaatattt gtgtaataac tatagtcatt ggtccaataa gtaagacggt tgtaacatta
    10861 tctaatacag ctgataaaat agctgttata atagcaaagc aaatcattat cttccatggg
    10921 tcacctttag ctttctttgc agtccagata gctatatatt caaataaccc cgagtttttg
    10981 acaacagcta caaatagcat cataccaact aatacaccaa tagtattgaa atctatatgg
    11041 cttaatcctt catcaagtgt aagtatattg aatattatca ttaatagtgc accaccaaca
    11101 gctgctacgg atctgtttac cttttctgta ataatagctg ccataactat taaaaatata
    11161 catatagcta ttatttgttg aaattccata atataagtac ctccatttgt attattttgt
    11221 gcctaatgct agtactatat atagtattac ttttttattg ttttttcaat ggatgtatga
    11281 aagtatatta tttaacaaag tttttgaaaa attgacagaa tttaaagaaa atttttgtta
    11341 tttaaataaa ttttaaaatt attccattga taataatatt aaacgacaaa cgaaaaaata
    11401 taccctttaa actagaattt attgtatcca ataacaatta taaaatatta aatatatcta
    11461 tattataaaa acaataaaaa aagctttgat ttgaatataa aactgcaata tattaaaaaa
    11521 attattcatt ttaaaccttg taatttgatt ttataaatat tataattaaa ttaatgaatt
    11581 tttaacaagg aattattcat ttttttgatt ttaagattta ttgagaaaac aaaactaaat
    11641 aggggggtaa ttaatataat ggattttttc aatggtattt taacgagtat taacaatgca
    11701 gtagtatatg taaacaatta cttatggtcg tatatcttaa ttataatgtt agttgtaatt
    11761 ggtatttact ttactattaa aacaaatttt gtacaattca gatattttat agaaatgttt
    11821 agacttctgg gtgatggtac agcgaataaa aatgcaaaaa aggaaggaaa aatctcttca
    11881 tttcaagcat tttgtataag tacatcttca agagttggaa ctggaaatat agctggaata
    11941 gcaattgcag tggtagcagg aggacctggt gctgtatttt ggatgtggct tatagcatta
    12001 attggttctg catcaagctt tgttgagagt acattagctc agatttacaa agtgaaagat
    12061 ggtcaagctt ttagaggtgg accagcgtat tatatggaac aaggtctaaa taaaaaatgg
    12121 atgggtattt tattctcaat acttataact atatgttatg gttttgtatt taatgcagtt
    12181 caagcaaata ctgtttcact tgcatttaat aatgcatttg gaataagtaa aatggctatg
    12241 ggaataggtc ttggaatttt aactgcaata gttatttttg gtggagtgca tagagttgca
    12301 aaagtttctg aaataatagt tcctgtattt gcaggattat atatattagt tgctttggct
    12361 atagttgtaa tgaatataac agagatacca agtgttatag cattgatagt tgaaagtgca
    12421 tttgatttta aaggaatggc gattggtaca tttatgggag ttgtaatgac tggagtgaag
    12481 agaggtctat tttctaatga agcaggtatg ggtagtgctc ctaatgctgc tgcaacagca
    12541 catgtaactc atcctgtaaa acaaggttta attcaatctt taggtgtttt tacagatact
    12601 ataataatat gtagttgtac agcattcatg gtattattat attcaggtta tagtagtagt
    12661 ggagcaactg gaattgaatt agctcaagaa gctttaactc atcatatagg accagttgga
    12721 aatatattta tagcagtttg tatattcttg tttgcattta gttctatagt tggtaattac
    12781 tattatggtg aatcaaatat ggagtttatg agtggaagta agactaaact taatgtattt
    12841 agagtttttg ttgtaggtat ggttttattt ggttcactta ctcaagtaga tgtagtttgg
    12901 aatcttgcag acttatttat ggcattgatg gcgataataa acttaatagc aatagcactt
    12961 ttaggaaaat atgcatttat tgctttaaaa gattatacaa gtcaaaaaaa atcaggaata
    13021 aaagaccctg tgtttattgc agatgaaata gaaggcctag aaaaggtatc agagtggcat
    13081 agggaattat ctgaggaaca tttaggataa aaaatagtat aaaattataa aaccattttg
    13141 aaagactaga gtatgtatat actttatatg aatataatat tgaattaatt tatattactg
    13201 gaatttttaa ttccagtaat atttttttat tatataattt agctttatta aaagttttta
    13261 ttattaaaaa tagcttattt atcgtaaagt gaatgatatt gggtttttaa ttattatgaa
    13321 tgttagtatt taatttaaag acttaaataa atttgccatt tctagcgcat tcatagcaca
    13381 atcataacct ttatttccag cttttgtacc tgctctttca atagcttgtt caatattttc
    13441 tgtagttacg attccaaata taacaggtaa ttcactgtct aaagatactt ttgctatccc
    13501 tttagagact tcactacata cataatcata atgagaagta gcccctctta taacacagcc
    13561 taaacagatt atagcatcat acttaccact tttagccatt ttttgagcaa caagaggaat
    13621 ctcaaaagct ccaggtaccc aaactatttc tatattttct ggagaaacgt catgtcttaa
    13681 aagacagtct tcagctcctg ataaaagttt tgatgttata aattcattaa aacgagaatt
    13741 tattatacct atttttaaat cttttccaat aagttttcct tcatatatca tttttacttc
    13801 ctccaatttt atttatgtta tagatttata tttataaatg tctttaattt aattataaaa
    13861 aactacttag tagaaaaata tcatcatata atcatttata taatatctaa aagatgtccc
    13921 attttatctt ttttagtttt taaatatagc ttattaaagt cattaatttc ttcattaata
    13981 gggattctat tttcgatttt tattccatat ttctctaatt gatttatttt atctgggtta
    14041 ttacttaaaa gatttatact ttttatgttt aaatttttta atatttgagc agccatatag
    14101 aaatctctca tatcttcttc aaatccaagc attaaatttg cttcaacagt atcgtaacct
    14161 tcttcttgaa gtttataagc cttaatttta tttaaaagac caatacctct accttcttgc
    14221 ttcatataaa ttaaaactcc acttccattt tctacaattt tcttcataga agattctagc
    14281 tgtaatccac aatcacattt tagagagtgg aacacatctc ctgttaaaca ttcagaatga
    14341 agtctaacta gagtattttc tatatttata tttccataag taagggcaat gtgttcttca
    14401 tttgaataag catctctata tcctatgatt tcaaaatttc catattttgt cggaaggaaa
    14461 gcactagata ctttttctat agtagtttca tttattttgc ggtattctat aaggtctttt
    14521 atagtgatga tttttaaatt atgcttttct ttgaaaatca ttaaatcatc aactcttgcc
    14581 attgtaccat catctttcat tatttcacag ataagaccaa tctctttaaa acctgcaagt
    14641 ctagcaaggt ctactgaggc ttctgtatgt ccatccctga caagaactcc accagttttt
    14701 gctattaaag gaaagatgtg accaggcgtt ttgaaatctt tacttgtaga attttcatca
    14761 cagaacaatt ttacagtttc agctctttca tatgcagata taccagttag agtatctgct
    14821 ccatctatag taacagtaaa ggctgtttga aatgtatctg tattttctct aaccataaga
    14881 ggtatattaa gacttttaaa ttttttttca gtggcaggta gacaaattag acctctacca
    14941 tatgtagcca taaaatttat tgattcagga gtagccattt cagctgccat caataaatct
    15001 ccttcattct ctctactttc atcatcaact acgattacca ttttcccatt ttttatatct
    15061 tcaatagctt cttcaatagt attaaacatg taattcactc ctttattatt tttaaaaacc
    15121 atttttaaat aaaaaatctt tatctatatt tgatttatgg ttactactat tagaatttaa
    15181 ttccttgtag ttattagcca taaaattatt aacatacttt ccaattacat cgctttctaa
    15241 attaacgaaa tctccaacat tctttgtcaa gagaatagtg ttaattttag tatgaggtat
    15301 aatagaaacc ttaaatattt catcatctaa atatgatata gttaaactta caccatcaat
    15361 agcaacagaa cctttgagta tcattgagga taaaagtttt ttatcaggtc gtatacttac
    15421 taaaactgca ttttcatctt tttcaaattt gcagatagtt cctttaccat caacatgacc
    15481 tgttactata tgaccaccaa atcttgaaga aagactcata gctctttcaa gatttacctt
    15541 gtcatttgca tttaataaac ctaaatttgt ggaacgaatt gtctccatca taacatcggc
    15601 tgtaaattca ttttttccga ggtttgaaac agttagacaa actccattta cggctatact
    15661 atctccaaga tttgtgccat ctaatatttt atttgatagt atggttactt ttccactctt
    15721 accattagca gtaatttttc taagtattcc aacttcttct actatgccag taaacatcct
    15781 aacctcctat atgaatgtat taacaaaaat ttaatttaaa acatctgatt ctataagaat
    15841 atcgccatct atcaaagtta cattattgat tgttaactgt gttgaatctg acaaatgatt
    15901 tattccttct ccagaaacga atgtaggtgc atctttacca cctataatct tgggtgatag
    15961 aaataatttg actttatcaa ctaacttatt tctaaagaga ctgtcattga gagtagcacc
    16021 accttcaact agaacagaat caatgtttaa ctctcctaat ttatacatta caaactccaa
    16081 atctactaag ttgttttttg aaggagaaat tattgtttca acattatttt cttttaacat
    16141 agataatttt atactttctt tgcaacatgt gaaaactata gttttactgg ttttatcttt
    16201 aaccaaatta ctattaagtg gcaactttag gtgtgtatct attactattc ttgtaggatg
    16261 agacactttt tcttgattga gcctgcaagt tagtaaagga ttatcgttca aaactgtatt
    16321 tatgccaacc attatacttt ggtatttatt tctgtattta tgagttagat accttgatga
    16381 ttcattagat atccattttg attctagtga ttttgtagca attttaccat ctagacttac
    16441 tgctgatttt acaatacaaa gaggtctttt gttttttata tgataaaaaa atgcctcatt
    16501 taaatctctt gcttcatctt ctaatattcc cacagtaaca tcaatattgt tatcttttaa
    16561 tttttttact ccattaccac aaacaagtgg atttgggtct aatgtagata ttacaactct
    16621 cttaatctta ttttgtataa ttttatctac acaaggaggc gttttcccat aatgagaaca
    16681 tggttctaag tttacataaa gagtagagtc ttttagactt tgtttagcac tgtttatagc
    16741 atttacttca gcatgattag agccaaattt ctcatgatat cctttgccta ttatattact
    16801 atctttaaca attacacacc caactaatgg atttggattt acaaagcctt ctccattttt
    16861 agccaattca atagcttttt tcatataata aatatctttt tctttttgat tcacaaaatt
    16921 cacaatatgt acacctccta tttaattgga taatttttaa acaaaaaacc ctgagaatta
    16981 actcagggtt tagaataatc tacaataaat gtttaataaa tgtagaacaa aattgctcta
    17041 caaaaacact cattaaatat cttcttccat ccagacttta ctgtcggctt tggaatttaa
    17101 ccaaatcaac caagttttac cttggctcgc gggctatacc gccgattggg aatttcaccc
    17161 taccccgaag attaagtatt aaatttatat ttagaatgta tcataaatta ttttactttg
    17221 caaactattt ttttaaaaaa tatatgttaa tatataatat agaatgtcta taaactttga
    17281 aataccacga ttgtgaatat aaaaataaaa atttgaacat aatcaggaaa gaagtctaat
    17341 taatttaaat taggagagta atatatgaat aaaaaacttt tagaaatact atcaaaatac
    17401 tatggatata caagttttag aaaaggtcag gaatctataa taaattctat cttaagcgaa
    17461 aaagatgtgt tagctattat gccaacagga gggggaaaat caatatgtta tcaaattcca
    17521 gctttgattt tagatggaat gacaatagta atttctccac ttatatcact tatgaaagac
    17581 caagtagatg ccttaaagac tatgggaatt agtgctgctt ttataaatag ttcattaagt
    17641 agcaaagaat ttaatgaaat attaaataat attagaaaaa ataattataa aatactttat
    17701 attgctccag agagattaga tgcacaagag tttattgagc taataaataa taacaatgta
    17761 agtcaagttg cgatagatga agcacattgt gtatctcaat gggggcatga ttttaggttg
    17821 agttatagaa ggatttctga ttttataaaa aatttgccta aaagacctat agttacagca
    17881 tttactgcaa cagcttcaga agaggtaaga actgatataa taaatttact gtgtttagaa
    17941 aatccagatt attatataac tggatttgat agagagaatt tatcaataaa tatagtaaaa
    18001 tcatctagta aaaataagta tattttagat tatattcaaa atcataaaaa tgagtctgga
    18061 attatatatg ttgcaactag aaaggaagtt gaaaatatat ataatggttt atctaagaga
    18121 aatgtatctg tgtcaaaata tcatgcaggt ttatctaaaa atgaaagaag taaaaatcaa
    18181 gaagatttta taaatgataa tgtggatata atggtagcaa caaatgcatt tggaatgggt
    18241 attgataaac ctaatataag atgggttata cattacaata tgcctcaaag tatagaaaac
    18301 tactatcaag aaataggtag agctggtagg gatggagaaa aaagtgagtg tgtactttta
    18361 ttttctccag gagatgtaca tatacaaaaa tatttaattg atattggagt tgaaaatcct
    18421 gaaagaaaat tatttcagca taagaagctt caatacatga ttgacttagt ttacagtaat
    18481 tcatgctata gaaagacaat attgagttat tttggagaaa attatataga caattgcaat
    18541 aattgtagca attgtttagt agagggtgaa atagtagata aaactataga tgcacaaaaa
    18601 gtcatttcat gtgtagctag aatgaaaaga agttatggtg ttactactat tgtagatgtg
    18661 cttagaggtt ctaagaataa aaagatttta cagcttggat taaatacttt gtctacatat
    18721 aacattatga gagattattc tagtgaagac ttaaagaatt ttataaatac attggtttct
    18781 catggttttt tagatttagt tgagacccta ggcaatggaa atagaggtag ttttcctact
    18841 ataagattaa atgagatgtc tatgaaagtt ttaaaaggtg aagtgaaagt agagtttaaa
    18901 gaaattgtta tgacaaaatc attggaagta gaggatgagt tatataatgc tttaagagaa
    18961 cttagacatt caattgcaag tgaagaaagg atagctccat atatggtatt tggagatggt
    19021 acacttagag ccatgtctag tagttatcca atcaataaag aagaaatgct agatatctct
    19081 ggagtaggag aaattaaata tcaaaaatat ggtagagatt ttgaagcagt aattaaagaa
    19141 tatgtcgaaa aaaataatat aaataaaaaa atagatgaaa aaaatgtcga ttcaaagaac
    19201 gttaatagtg atttcttaga ggttaataca gataaagttt tatatgaaaa actgttagtc
    19261 attagagaag aatatgcaac aaaggaaaaa ttacctgcat atatgatttt agccaataag
    19321 gctttgaaag aaataagtgg aagatatcca cttgatgaag aacaattaaa agatatttct
    19381 ggcataggtg gagtaaaatt tgaaaaatat ggagctagta ttttggcaga ggttaataaa
    19441 tatgtaaaag aaaataatat taatgttatt tgggagaaaa agggcaaaag gaagttaata
    19501 ttagatggag aaagtagaaa aaataatgaa atagcattag atttgctaaa tcaaggaaaa
    19561 gatatacaaa gtatcagtca agaaatagaa gtttcactgt caactattat tggatatgtg
    19621 catgactatg taaaggatgg acatagtata tcatttgaat taggactaga aaatttttat
    19681 aatgaagata aaaagaagat gattttagaa gtttgcgaaa aagttggcta tgataattta
    19741 aataacataa aaagaaaact tccagattca ataaagtatg aaaatataag agctgtgata
    19801 cttgactctt atcttgaaaa cttaaaaaat aatattatag cagagtaatt tttaacttaa
    19861 taaaaaataa aatttgtatt attgtgttga actaataatt ttgctgtgtt atactgaatt
    19921 tgtaaaaata atgaaaaatt agagctaggg gcgctagaat tggctagctg agagataaag
    19981 ccgtaactta caaaccctaa taacctgatc aagataatgc ttgcgaaggg aagcttttta
    20041 atataatttt attatataaa taggcaaatt attcaatgtt aggagaaatt tgtctaagtg
    20101 tatatacgat tataagagtg ctttccaaac gaggaaaagc acttttttta ttttcaaaaa
    20161 ctataacttt aatcttggag gattgtaata tgaactatac aacacaaatg gatgctgcta
    20221 gaaaaggcat aataactaaa gaaatggaaa tcgtttctca aaaagaacag gtagatgtaa
    20281 atgaattaag agaattaata gcaaatggac aagttgttat accagctaat aaaaatcata
    20341 aatctttaag tgcagaaggt gtaggtaaaa atttaagaac aaaaataaat gtaaatctag
    20401 gaatttcaag agattgtaag gatatagaaa aagaacttga aaaagttaga gtagcaatag
    20461 acatgaaagc tgaagctata atggatttaa gtaattatgg caaaactaga gaatttagag
    20521 aaaaggttgt tgaaatgtca cctgcaatga taggttcagt acctatgtat gatgcagtag
    20581 gatatttgga aaaagaatta aaagatataa cagaagaaga gtttttaaat gtaataagac
    20641 aacatgctat tgatggagta gactttatta ctatacatgc aggtcttaca agaagtgttt
    20701 gccaaaaaat aaaaaatcat gagagattga ctcatatagt atctcgtgga ggctctttat
    20761 tgtttgcatg gatggaatta aataataagg aaaatcctat ttatactaat tttgataaaa
    20821 tattggatat atgtgaagaa tatgatgtta cattgagttt aggagatgct tgtagaccag
    20881 gttgtataaa agattctact gatggtgttc aaattcaaga acttgtagta ttaggtgaac
    20941 ttactaaaag agcatgggaa agaaatgtac aagtaatgat agaaggtcct ggacacatgg
    21001 ctattgatga aatagaagca aatgtagtat tagaaaagag attatgccat ggagcacctt
    21061 tttatgttct tggaccattg gttacagata tagcaccagg ttatgaccat ataacaagtg
    21121 caataggagg agctttagca tgtgctaaag gagtagattt tttatgttat gtaactccag
    21181 cagaacattt aagattgcct aatttagatg atatgaaaga gggtataata gctgcaaaga
    21241 tagctgctca tgcaggagat atagctaaaa atgttaaagg tgctcgtgaa tgggataata
    21301 agatgagtaa agctagagct gatttagact ggtgtgagat gtttagactt gcaatagacc
    21361 ctgaaaaagc taagagatac agagatgaat caactcctac tcatgaggat agttgtacta
    21421 tgtgtggaaa aatgtgctca atgagaacag ttaagaaaat attaaacaat gaggaactta
    21481 atctaatata attcttggct agtatgactg gaataaaaat aagctgaaaa gaggaggtga
    21541 tttagtgaag gttaatggga aggaaattga atttgaaaaa gatttgactg ttatagattt
    21601 attaaataaa tataatttaa aaagtgatag agttgtagtt gaagtgaatt tagagataat
    21661 tgaagaatct aactacaata catatgtatt aaaagacgag gacattgtag aacttattag
    21721 ctttattgga ggtggttaaa ataaaaatat ttgtaaatga attgttaaca gatgttgagg
    21781 aaaatacaac tgcttataaa gttagagata gctataacaa taaatgtgat gtattggtgt
    21841 taaatggata tccaattaaa acagatatgc ccctttgtga aaatgataaa ttaacactta
    21901 tacaaaaagg agttaagcca tcacttgatg aattagaaag cttgttgatt gctagacata
    21961 ctccaaatat acataataaa ttaaaaaaag ggaaagttgc tatattggga ttggggggac
    22021 ttggttccaa tatagctatc tctttagcta gaataggagt gggagaactt ttacttatag
    22081 attatgatgt tgtagaacca tctaatttaa atagacagca gtattttata gatgatatag
    22141 gaaaactaaa aactgatgcc atgatagaaa atataaaaaa aataaatcca tttataaaat
    22201 taaataaacg agatattttt ttaaacaaga acaatatgga tactattaag gattcagatt
    22261 taataattga ggcctttgat gatgcttcat gtaaagcaca ggtatgtaat tatgtattaa
    22321 taaatttaaa agataaatat ttaatagcat catctggtat ggcaggttac tatgattcaa
    22381 atataataac tactaagaag ataaaagaca ggttttatat atgtggcgat tttgtgaatg
    22441 aagctaaatt tggtgaaggg cttatggctc caagggttgc catctgcgca aatcatatgg
    22501 caaatttggc aacgcaaata cttatagata tgtaaatatt aaaattagat ataaaaaaga
    22561 ttgaatatta aaaaagttta acgtggaggg aaataatatg gataaattgg tacttggtgg
    22621 acatgaattt aatagcagat tattggttgg aacaggtaaa tatggttcaa ataatatatt
    22681 gcctgaggta ataaaagaaa gtggaagtga aataataaca atggcactta gaagagtgga
    22741 tttagacaat aaacaagaaa acatattaac gtatattcca aaagagatga caatacttcc
    22801 aaatacatca ggagctacta atgcagaaga agctgtaaga atagctagaa tatctagaaa
    22861 aatgggatgt ggagatttta taaaaataga agtaatatca gatactagat atttacttcc
    22921 tgataatgaa gaaactataa aagctacaaa gatacttgct gatgaggggt ttatagttct
    22981 tccatatatg acaccagacc tttatgctgg aagaagactt atagaagcta atgcagcggc
    23041 agttatgcca cttggagctc caattggttc aaatagaggt cttcaaatga aagaaatgat
    23101 aagaataatg atagatgagt tggatatacc aataatagta gatgcaggta ttggaaaacc
    23161 atctcaagct atggaggcta tggaaatggg agctgatgca gtacttgtca acactgctat
    23221 agcttcagca ggagaccctg tacaaatggc tagagcattt aaattagctg tagaaggtgg
    23281 aagagaagca tatattgcaa aaacaggaaa tgtgtcagaa tttgcaaatg catcttctcc
    23341 tttaacaggt tttttaggca atttatagaa agtggtgatt ggtgatgagt ttttatgatg
    23401 taatagaaaa atatagggat tttgattttg atggatattt aaataatgtt actgataatg
    23461 atgttttaag aagtttatca aaagacaagc ttgaagattt tgatatatta aatttgcttt
    23521 ctaaaactgc agtaaaacat ttagaagata tggcacaaaa agcacataaa ttaagtgttc
    23581 aatactttgg taaaacagta tgtttatata caccaatgta tatagcaaat tattgtgtta
    23641 atcaatgtgt ttattgtagc tataatataa agagtggaat aaaaagaaaa aaattaacta
    23701 tggatgaaat tagagaagag ggagaagcaa tttcaaaaga aggtttcaaa catctacttg
    23761 ttttgactgg agaaagtagt tttcactcaa gtgtagaata tataggtgag gctatagaaa
    23821 tattaagaga gaaatttccc tctataggta tagaagttta tccaatggaa gtagaagaat
    23881 ataagtacat tgtagataaa ggtgttgaag gattaacagt atatcaagaa acttatgacg
    23941 aggaaatata taagagagta catataaaag gcccaaaatc aaattataaa tttagactag
    24001 atgctcctga aagaggggca aaagcaggta tgaggacttt atcaataggt gcacttttag
    24061 ggctaaatga ttttagaaaa gaaacttttt ttacaatatt gcatgggaaa tacttaaaaa
    24121 cgaaatatcc tcatattgag ctttcatatt caacaccaag aatgagacct tttaaagggt
    24181 gttttgagga attggtagat ataagtgata ctgatttagt tcaagctatg gtatgtatga
    24241 gattatttga ccctcatgca gctataaata tatccactag agaaaattta gaaatgagaa
    24301 gtcatataat acctttagga gtaactaaat tgagtgcagg tgtatctact gatgtaggag
    24361 gtcattctca agatgaacat gatactgctc aatttaagat aaatgatgaa agtactgtta
    24421 aagatgtgga gaaaatgcta aactcaattg gttatcagca tgtgtttaaa gattgggaaa
    24481 gattttaaat gtatctgata acaaacagaa aattatgtag tgaggaacga tatttagaag
    24541 ttattaaaga gtctatattg agtggtgtag aaaatataat aataagagaa aaggatttgg
    24601 aatatcaaga gctaaaaaaa ttatatatga aaataaaaac taaaatcaat tgtatagatt
    24661 ttcaagagca aatatcagat gaaagtttga aaactaatat aaatcaaaaa gagtgtagaa
    24721 ataaattcaa ggttaatttt ataataaata gtaacattga attttttgaa aaagtggatt
    24781 gtcaaggtat ccatcttcct tttaaattat tcttgaattt aattgaaaat aagtataatt
    24841 ttaatgaaaa taaaatacta ggattatctt tacataaagt agaggaagta gattatttag
    24901 aaaaattaat aagaaatcaa aatataaaaa tagattacat aacattatca catatatatg
    24961 aaactaaatg taaagaagga ttaaatccaa aaggaattga gcttttaaaa gaagctaaaa
    25021 agattactga tattaaaata attgcacttg gaggaatttt accatctaat gtcaaagaaa
    25081 cattaaaata ctgtgatgat tttgctataa tgtcaactat aatgaggtct aaagatatta
    25141 aaaaaaccat atcaaattat aatgaaaagt tgaattagta aatatagtat attgaatttt
    25201 taacttaaat aaaaataaaa aagttatctt ttaaatttta aaaggtagct tttttatttt
    25261 atatctttgc taataaaaaa ttgtaaaaag ggaaaacttt agtcagagag attaaacaat
    25321 atcctagaaa gatttaaaat ttagtaaagt atggaggaca ttataatgac tgacagtaaa
    25381 aagaaacgat ttattatacc acacactttt acaataatat ttttactaat agtcttgatg
    25441 gcaatattga cttggatagt accaagtggt gaatttagta gagaagatgt agaaggtaga
    25501 atggtagttg taccagggac ttatcaaagt gtagaaagta atcctcaagg atttgcagat
    25561 gtttttaaag caccaataga aggctttatc gattcagctg aagttgtagg ttttgtttta
    25621 atagttggag gtgcttttgg tattgtaaat aggactggag ctatagaagc aggaatagct
    25681 tcggttatct ctaagtttaa gggaaaagaa cttcttataa ttccaatatc aatgatttta
    25741 tttggacttg gaggtacaac atttgggatg gcagaagaga cattaccatt ttatatgata
    25801 tttgttccac tcatgacatc cttgggatat gattctctaa cagcaatagc aattgtattt
    25861 ataggagcag cagcaggagc cgccgcttca acaataaatc cattttcagt tggtattgca
    25921 caggcactag ctcaacttgc tcctggttca ggagtaactt acagagtagt tatttttata
    25981 gcatatatac taataagtat agcatttgtt atgtactatg ctaagaaggt aaaggaaaat
    26041 cctgaaagtt caatagtata tgaaatagat aaaaataata aatcaatact taatcaaact
    26101 tcaacagaaa taaaagaatt tacttttaaa gaagtatctg ttcttgctat atttggaata
    26161 gggatggcaa taatgatttg gggtgtttta agtcagggat ggtacattcc agaaatatca
    26221 atgtgttttg ctgcaatagg tgtgctttct ggattggttg gtagattatc tcaaattgaa
    26281 atctcagaaa gttttataga tggagcaaaa gatttagcat ctgcagctct tgctatagct
    26341 ttggctcgtg gaatcgtaat aattgctcaa aatggattta taatagatac tatattaaat
    26401 tccgcagcag cctttctagg tgggcttcca aaggttatat ttgtatattt atcatttttc
    26461 ttggaagctg cattggcatt tttaattcca tcatcttcag gtcttgcttc acttacagta
    26521 cctgtacttg ctcctcttgg tgatttggtt aatatatcgg ctcaagtgat agtaaccgct
    26581 tatcaatttg gtgtgggtct tacaaacttt ataactccaa cttcaggagt actgatggga
    26641 gcacttgcag tagcccatat tccattttca aaatgggtaa gatttataat gcctatcttg
    26701 ttgattttga cagctgtatc tctagtcttt ttaacaatag gtatttatat agggttttaa
    26761 ttaagtgtag ttttatttaa gatatttagt aatggtataa aatgataata tgttttcaat
    26821 aaattgccac taatttaatt agtggtaatt tgttttttgt atttaaaaat aaatgtattt
    26881 acttgtattt tgaattaata tctacttaga cattgtttta attgttatat tttcatttaa
    26941 ttaagcattg atttatcatt ttttatattt catataacaa tgcaaaaaat aatttttata
    27001 tagtaaatga caaaagttta caataaatgt atattttctt actcattcct taaaattact
    27061 catttagttt aataactctc atttcatatg taaagttggt aaaaaaatta aaattaaaag
    27121 taaaaaacta aataaattaa tgttaatttg aaatatatat gaaggttttt ggagaatact
    27181 tacttatgat aggaaaaaat gttaaaataa tagtgtaatc aaatataaag gactgaaata
    27241 attaacagtt attaaatatt aggagtgtaa aaatttatgg gattaaaaga atttgatttt
    27301 attgaagagt ctattgatat gttgaggaca atgtcaccaa cattagaaac tatatcagat
    27361 gaaatagaag agtattttga aaatatcttg gatgaaaaga atcaagaata tataaatgta
    27421 acctctagaa taaaatcaga atcaagttta agagaaaaga taattagaaa tagatattta
    27481 aaaaaatatg gagaagcaag taatcttatt cataatgttt ctgacttaat aggcctaaga
    27541 attgagtgta gatttattga ggatgaaaac aaaatatata gacttttgag aagatatttt
    27601 aataaaacag atgacaaaat aaactattat aataaagaga ataagaatat taaattaaaa
    27661 ctatctgaga ggcaacccaa taagcaaaaa aatggatttg aaatatataa aatagatgga
    27721 gtttttgcgt atttagatag agaagtaaaa tttgaacttc aaattaaatc tcttgtaaat
    27781 gtgttttgga gtgaaataga acataaaata atttataaaa acaatacata tttacttgct
    27841 gataaattta taaaggatat gatggactct ataaagaata atcttactat gatagataat
    27901 cagcttttaa gtatttataa aaactttcat tcagggaagt cttttaatat gaaagtaagt
    27961 aaaaaagaaa ttgaaaaatt atttgcgaaa ctagtctatg acgctttttc tgaaaagatg
    28021 aataaaagta taggttttgt tgtagatttt aaaaaaccat gtgagactat attgaactat
    28081 tcttttaata aacaagatat aagtgatgaa gttttaggta attttatgct tgatgagttt
    28141 gcaagattaa atgaaattgt aaacaaggat atagatttta atgagcaaat agaatttgaa
    28201 agagaaccaa catttgatga taagttttgt aaagacctag gaaatcattt tagaagtaga
    28261 ttaaacacag aatttccatg gaacctattt tttagaatat tatttgaaat agagccatat
    28321 aacaatacca aagactttga aaactttgta gagtttataa aagaaaatgt gctactagaa
    28381 gaaaataggg agcaattatt atgccaattt gaagaagata gcaagcttat aattgaagat
    28441 atatatgatt gtatatttaa tagtataagt gagattgata gtgttgaaat tttatataac
    28501 tataatcttg aaaaaataaa ctttacatca agtgaaatca taaattgtat atgtagagaa
    28561 tatgagtgtt atggtgaata cttagaagaa aaagaaaagc ttatgaatac atttaaagaa
    28621 aagattattc aaatctttga gtaataggtt aatgctgaag tggcgctaat gcgccatttt
    28681 tcaaatatat atgaattaag taaaattatt ttggaggagg cgatttgtat agagaaaaca
    28741 ggtgtaattt tggcaggggg aagaaattct agaatgggta gagataaagc ctttttagag
    28801 ttacatgata agctttttat tgaaattgca atagaagcat ttaaaaactt tgatgagttg
    28861 ataataatat ctaacaatga agaattatat tctaaatacg atattaaagt ttataatgat
    28921 atagtaaaag atgttggtcc aattggagga atatatactg ctcttgaata tgcaaagtat
    28981 gatatagtta caattgcatg tgatatgcca tatctaaata atcaaatagt cgaaagaata
    29041 gctaataaaa tggatgataa aagtgtgatt tcagtgacaa atggaaagtt acaaccattg
    29101 tgttctggat ataaaaagag tataataaat aaagtatctt tatgtataag ggaaaatgat
    29161 ttaaagctca gaagctttat agataaaata gataaaagtt atatatactt tgatgaagaa
    29221 gatttatttt taaatgtaaa cactgttgat gagtataaaa aattaactaa agtttaatta
    29281 gctatggttg taaaatagag taggatttat atggaggaga gtttatgaat ttacttaaat
    29341 gcgattcttg ggcagtaata ttaaataata gcgataaaga aagtaaagca tataaaatat
    29401 tagatgaact taaaaggaat atgtacaaag ttgttgctat agatgaagag aaaaaaccta
    29461 ttgaaggaat agatgtgtat gaatgtttaa aagatgttcc acacaatatt gatgttgtag
    29521 ctattattga taaacaatct aagatggatg tgattttaga agaagtagag cttttggata
    29581 tacaaaatat gtggtttgaa aaaggaagct ttagtgaaat gatgattaaa aagactaaag
    29641 atttaaaatt aaatatagaa tataatttaa gtttatatga tgagttgact agataaaatt
    29701 atatttctta ataataaaaa tataattagt taataaaaca tattatttta tagtatagat
    29761 tggttaataa aagtacagat tggttaatga aacattaaat tacaatattt gttaaaaaaa
    29821 ttgtgagtta catgatataa tgtattaaat aggatactaa ggagttgata tattatgtta
    29881 atagtaacta cagaaaaagt agaaggtaaa aagatatcaa aggttttagg attagtgaga
    29941 ggaagtacaa taagagcaaa acatgttgga aaagatatag gagcaagttt taagaatctt
    30001 gttggaggag aacttactgg atataatgaa atgctcactg aagcaagaca aattgcgata
    30061 ggtagaatgg ttgaagatgc agaagctaaa ggtgcaaacg cagtaatagc atttagactg
    30121 tcttcagctt cagttatgca aggggcagca gaaatgcttg cttatggaac agcagttgtt
    30181 ttagaagatg ataatagtat tcttgaaaaa taaaatataa atagttaaaa agaggcatct
    30241 tttaaaaatt ttatggatgc ctttttttat ttgaaaaaac taatttgaga agaaatttta
    30301 actattatga caataaaatt agggtgatat tatataaata agtaaaatta tattatataa
    30361 tgtatggtat agactttaaa aattttattt gtagagaaaa atatggataa tgttataata
    30421 attatagaaa ttaaaagtac ttacattcat tatgtatgtg acatgtataa ttagttttat
    30481 atttaataca gttttgaagt aatatcttca ttttgagaac gttggaataa taaaaaatgt
    30541 atgtattata ggtgatataa ataaaaaata aatataatat gttatattgc tgatagaaaa
    30601 gagaataaaa gaaaataggt tttattaaaa gagattttta tttataggac ttaatcaatg
    30661 tatagagggg tgagaacata tgtttaatgt tgcaattata acacttagtg ataaaggata
    30721 tgaaggaaaa agagaagata taacaggaaa aaagttaact gaatttgttg aaaatacagg
    30781 agcttataaa gttactgaat atgtacttat aaaagatgat aaggaaatgc taaaggaaaa
    30841 tattataaga ctttgtaata gtaataaaat agatttaatt cttacaaatg gaggtactgg
    30901 tttttcaaaa agagatataa ccccagaagc aactaaggaa gtgttggaaa aagaaatacc
    30961 aggtctgagc gaatatatga gaatgaaatc cacagaaatt actaaaaagg ctatactaag
    31021 taggggtgtg agtggaataa gaaataattc tataataata aatttacctg gaagtcctaa
    31081 aggtgcagtt gaaaatctaa gttttataat tgatgtttta gaccatggca tagaagtttt
    31141 aagaggagaa gctacagaat gtgccactaa aaaaagtgaa tagtatataa tctagataga
    31201 taaaaaatag acaaagaggt agataaagta tgattgataa gtatggaaga aaaatagact
    31261 accttcgtat ttcacttaca gataagtgta atttaaggtg tgtctattgt atgccaccag
    31321 atgtaaaatt tgataaaaat tatataaatg aaaatctaag ctttgaagac tacaagttta
    31381 ttataaaggc tatggctgaa caaggtataa caaaaattag atttactgga ggagaacctc
    31441 ttttatatcc taaattaaat gagcttataa aatttacaaa agaagaatgt ggaataaata
    31501 acataggaat gaccactaat gctattggtc tttctgatag aatttttgag cttgaaaaat
    31561 gtggcttaaa taaagttaat ataagtttag attctttgaa ggaatataag tataaatccg
    31621 taacaagagg aggaaactta aaagatgtct taaaatcgat tgaatcttgt ttaaacttag
    31681 gtataaaagt aaagttaaat tgcgttgcta taagtgggtt taatgatgat gagcttaaag
    31741 attttatgtt tttaacagtt aaatcaccaa ttgatgtaag atttatagag cttatgccat
    31801 taggtgaggc taatagagtt tataagaagg gttattttaa tgtaaaagaa atgattgaaa
    31861 aaatatatgg tttatataaa gtcaaaaatg atgaaaaaag tacagcagaa tattatatgt
    31921 ttaaaggagc taaaggaaga ataggaatta taactccatt aagctgttca ttttgtaaca
    31981 cttgtaatcg tattagactt acttctagtg gtgcaataaa attatgtcta cattcaaaag
    32041 aagaaataga tataaaacca tttttacata aaccattgtt atttagagaa tctatgaaag
    32101 atataataaa acaaaaacca gaaaaacatc atttaataga aaataaatgt agtgatacaa
    32161 ataggcgtat gtatgaaatt ggaggataag taatgttaac acatataaat gaaaaagggt
    32221 atgccaagat ggtggacata agtgaaaaag atgatactaa aagaacggcc gtagctacag
    32281 ctacaattac tcttagtaag gaagcattag aaaaagtaaa aaatggtcag ataaaaaaag
    32341 gagacgtatt gtctgtagct caagttgcag gtataatggg agctaaaaat acatcttcaa
    32401 acataccaat gtgccatcag attaaattag ttggatgtga tttagaattt gatgtagatg
    32461 attctatgtc tgctattaag atatacgcaa cctgtaaatc tcttgggaaa actggagtag
    32521 aaatggaagc tttaaatgca tgttctttag cagcacttac aatttatgat atgtgtaaag
    32581 cagttgataa aaaaatggtt ataagtaata tccatcttgt ggagaagact ggtggaaaat
    32641 caggagattt taagttcgag taaattaata atatattggg ttaaaatttg gaggaaatat
    32701 ggcgaaggta gtgtcaataa atataagtga gaaaaagggt gtaattaaag ttcctgtaca
    32761 atgtgcagag ctaaaaataa accatgggat agttggagat gcacatgcag gaaactggca
    32821 tcgtcagata agcttacttg gaaaagaaag catagataaa atgaaaatga aaggctttga
    32881 ccaattaaaa tatggagatt ttgctgaaaa tgtaactaca gaagggatag aagttttttc
    32941 cctgcctgtt ggtacaaagt taagaatagg gcaatgtgaa gttgaagtaa ctcaaatagg
    33001 gaaaaaatgt cacaatggat gtgaaattaa gaaattgaca ggtgactgtg tgatgccacg
    33061 agaaggaatt tttgtaaagg ttctaaaaga aggaattata aatgtgaatg attcaataga
    33121 tgtaat
//
LOCUS       DAEORM030000042        33084 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.042, whole genome shotgun sequence.
ACCESSION   DAEORM030000042 DAEORM030000000
VERSION     DAEORM030000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 33084)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33084)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 33084)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33084
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.042"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            40..357
                     /gene="flgB"
                     /locus_tag="KRH23_002570"
     CDS             40..357
                     /gene="flgB"
                     /locus_tag="KRH23_002570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgB"
                     /protein_id="HHS5225848.1"
                     /translation="MNTYDIIKMGLDATNLRSQTIANNIANINTEGYKRHYVTFEETL
                     NDAMPKIEEKTDNSKGLRVDGNNVDIEEEKVNQAMTTLQYNALISFANGKIAMTKSII
                     SGR"
     gene            365..769
                     /gene="flgC"
                     /locus_tag="KRH23_002571"
     CDS             365..769
                     /gene="flgC"
                     /locus_tag="KRH23_002571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030694 - bacterial-type flagellum basal
                     body, rod [Evidence IEA];
                     GO_process: GO:0071973 - bacterial-type
                     flagellum-dependent cell motility [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgC"
                     /protein_id="HHS5225849.1"
                     /translation="MSVFSGMRISASGLTAESLKMDIISSNVANINATRGPNGEAYRR
                     KVVSFEENYDNKLGMLGVKVTSVEDDKSPLKEVYDPSHPDAKPNGYVEYPNVNILVEM
                     TDLITASRAYDSNVDTLNAQKSMISKALEIGK"
     gene            779..1096
                     /gene="fliE"
                     /locus_tag="KRH23_002572"
     CDS             779..1096
                     /gene="fliE"
                     /locus_tag="KRH23_002572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009431 - bacterial-type flagellum basal
                     body, MS ring [Evidence IEA];
                     GO_function: GO:0003774 - cytoskeletal motor activity
                     [Evidence IEA];
                     GO_process: GO:0071973 - bacterial-type
                     flagellum-dependent cell motility [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-basal body complex protein FliE"
                     /protein_id="HHS5225850.1"
                     /translation="MPITQINNLMQGAKLDNLIGEAKPLTLNNKEEKKNFEDVIIDTI
                     DKVNFQQVTADDMKEKFIKGEDVSMHEVMLIGQEAQLSMQYLIEVRNKIHDAYQEMNK
                     VQI"
     gene            1121..2671
                     /gene="fliF"
                     /locus_tag="KRH23_002573"
     CDS             1121..2671
                     /gene="fliF"
                     /locus_tag="KRH23_002573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009431 - bacterial-type flagellum basal
                     body, MS ring [Evidence IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0001539 - cilium or flagellum-dependent
                     cell motility [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal-body MS-ring/collar protein
                     FliF"
                     /protein_id="HHS5225851.1"
                     /translation="MITSFKNKIKEQVAKSRTKISSLKKGTKIALGIGVIAICLALVF
                     TAISASKNKYAVLFSELDAQDAADISAELESKKIDTKVKGSTIYVPRTEVDKLRLELA
                     PSLTGGSKGFALMDDSSSIGLTDEEFQIKKQRMIQGEIEKTIKSFPQVEDTRVHITFG
                     ESSVFEKEAVPGSAAVYLMLKPGTTLEKNQIKSVMALISGSVTNIPEKNVQVIDNKMN
                     LLSEGILEDENVDENNQPINSGISVDKNKASEQALNKQLEKSILEMLEPIFGKGKVKA
                     TVNADLSFDTAEKTEIKIDPDKVAIKETRSKNSSKSAANNVQGVDANMNNQGNNNGTN
                     TEDSLDESFEYETGKIETHTIVAPGELNRLTASVAIDGKIAKGVQADVEDIVNNAIGM
                     DGARGDTLSVVSMVFDPEGKKEAKQELEEIKKEGFKKNIIKAVIGVVAVIAVGAIGYL
                     IYKKRSEREDMDYEDEDYISKSDSVDKKDNPLLGDDPELTLEEAVKMYAEEKPDQVTE
                     IIKTWLNE"
     gene            2684..3754
                     /gene="fliG"
                     /locus_tag="KRH23_002574"
     CDS             2684..3754
                     /gene="fliG"
                     /locus_tag="KRH23_002574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009288 - bacterial-type flagellum
                     [Evidence IEA];
                     GO_function: GO:0003774 - cytoskeletal motor activity
                     [Evidence IEA];
                     GO_process: GO:0006935 - chemotaxis [Evidence IEA];
                     GO_process: GO:0071973 - bacterial-type
                     flagellum-dependent cell motility [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein FliG"
                     /protein_id="HHS5225852.1"
                     /translation="MSTEITNVNAFDLSDISESDKNEKIEGEGLKKAAVLLMTLGPDV
                     SSDIIKSLPDKQVQKIGLEIANISSIASKERREILKEFVEINRAKDYVIEGGLEYARE
                     LLSNALGNAKANKLLEGISINTSTKPFKHIIKLDVKKILEILRNESAQTIAVLLAHME
                     PENGAEVLSYLDFDLQNEVAMRISSMGSISPEVIKVIESSLEDKLHSISGDDFNDYGG
                     VSTLVQILINSDRKTEKNILGTIEEQNPDLAAQIKSHIFVFEDIVKLDDISIQKVLKE
                     VTMKDLVYALKGVDDEISDAIYRNQSSRAADALKEEMEMVGVIKVTQVEASQQKIANI
                     VRKLEREGAITIVRNFGGDFVE"
     gene            3738..4478
                     /locus_tag="KRH23_002575"
     CDS             3738..4478
                     /locus_tag="KRH23_002575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliH/SctL family protein"
                     /protein_id="HHS5225853.1"
                     /translation="MTLLNNKIIKSKKALYKGVLDLTIIDKVRVGESNVNKENDCRFR
                     DEVIKEAIESAEIKKNEILEEAKINAQNIEKQAYEKGYSQGQKNGYEDGYKESYDEYT
                     QKAKDEADFIKNQANLILLQANEKMTEYIKEKNKEIVRLAINMASSVLKKHFEDEESM
                     SDLLKQIIQDYEGNSSFIVRCNSFYKDNIEKEFELFKEETSLKSSVFVIADDSIDKGN
                     AIIQKENGRIIVGIDCAMEKLKEELLGE"
     gene            4482..5801
                     /gene="fliI"
                     /locus_tag="KRH23_002576"
     CDS             4482..5801
                     /gene="fliI"
                     /locus_tag="KRH23_002576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0044780 - bacterial-type flagellum assembly
                     [Evidence IEA];
                     GO_process: GO:0071973 - bacterial-type
                     flagellum-dependent cell motility [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein export ATPase FliI"
                     /protein_id="HHS5225854.1"
                     /translation="MYKTDISIDFDKINKKIENLELTISEGRVKKIIGLTVEVEGIKA
                     FVGELCVIYNQVNKPVNCEVVGFKDKEVILMALGELTLIAPGCKVISKGIPLSVMCSD
                     NLLGKVLDGLGNPIDNSDAVLGDRYNLNNEPPDPMKRKKIRNIMETGVRAIDAFTTCG
                     EGQRIGIFAGSGVGKSTTLGMIARNAKADVNVIALIGERGREVLDFIDKDLGEEGMKK
                     SVVVCATSDKAPLVRLKGALTATAIAEYFRDQGKKVILMMDSVTRFAMAQREVGVAIG
                     EPPAQKGYTPSVFAMLPKLMERTGTSDKGSITAFYTVLVDGDDFNEPIADTTRGILDG
                     HIVLSRDLANKNHYPSIDVLNSLSRLMNEIASKEDIKIASFARDMLAEYREAEDLINI
                     GAYASGTNKKIDEAIYYHEHIINFLKQGINEKSSFNETISSLRRVFE"
     gene            5832..6278
                     /gene="fliJ"
                     /locus_tag="KRH23_002577"
     CDS             5832..6278
                     /gene="fliJ"
                     /locus_tag="KRH23_002577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012815984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009288 - bacterial-type flagellum
                     [Evidence IEA];
                     GO_function: GO:0003774 - cytoskeletal motor activity
                     [Evidence IEA];
                     GO_process: GO:0071973 - bacterial-type
                     flagellum-dependent cell motility [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar export protein FliJ"
                     /protein_id="HHS5225855.1"
                     /translation="MELDKNFKFRLQKVLDLKVKDEEEIKMEFAKIQQKKIDIETNLE
                     NLESNYSKYSISKNNDSIQNQKITINYLLALNNSIMDLSEELDKSTNELEKARKQLIS
                     KQIERKSLEKLKEKKYGQYYKEENLKEQNTNDEFASMSYLRNRQVL"
     gene            6307..7512
                     /locus_tag="KRH23_002578"
     CDS             6307..7512
                     /locus_tag="KRH23_002578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-length control protein FliK"
                     /protein_id="HHS5225856.1"
                     /translation="MKIQADSYNIIKDIGDRKSSSKNKNIKNNKFEDNLYKATDHKKV
                     KDRREVSKQNISSDKPENSDNECHLDEDKSNHLEDENTYEKDCSKNNEALQQLLNLLK
                     DNYKKDKDINTILDNIEKLSISDELKQELKLNKNILNKIANQNSELNKANINNSNDIE
                     NLDIVKLRELLEDSANKDIEVISKTTENDTKNIDLYSFDSNRMDNLNSNKQKDDSSDI
                     LEKLAGVNGNKSGNFGQVINKNVDMNKLKNDNVNLKQIESNVMDDSIKAIKHMKTNDI
                     QELTIKLRPKELGDMNIQLLKDGESMRAVVTVFNKDVFDSINKNISDLKQHLELTNVN
                     IKDVSVQMHSDNTNTSDTFDKAFEQQNRQNNQENMSKKNTNDKHNNVVIEDDIKENII
                     DDDRVDLLA"
     gene            7530..8138
                     /locus_tag="KRH23_002579"
     CDS             7530..8138
                     /locus_tag="KRH23_002579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook assembly protein FlgD"
                     /protein_id="HHS5225857.1"
                     /translation="MYGIATALAGTQGNYRSNNLSQLERNINDIANKQVRSKGNQTVT
                     DNGTPIIGQGDDADKDLFMKILVAQMGNQDPMNPQDPTEYVSQLAQFATLEKMSAMNE
                     KLDVLLALSNSTLINSALSMATSLIGKEVEVSGEEKEDENIVGVVKSTYIKDGEVHLE
                     LEVDGSDKTVGVKYEKLLKIGEVDENSGEENDSSEHESPEEA"
     gene            8165..9148
                     /locus_tag="KRH23_002580"
     CDS             8165..9148
                     /locus_tag="KRH23_002580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-basal body complex protein"
                     /protein_id="HHS5225858.1"
                     /translation="MIKAMYSGVSGMKANQTKLDVIGNNVANAGTTSFKKSSARITDS
                     FYQTVLYASAPTAALGGTNLGQVGVGSKISSINKDMVQGNVQPTNRPSDLMIDGDGYL
                     PVVRQGTVMYTRDGSFNLDTGFKAADGALKNIKGGRLVNGDGYMLQGMIYDGEYKADT
                     GEFVKKGDAKGKEPIVIPLQSISPKDGTVQNVLEYNISKDGTVEFLLSDGQRTQFVYD
                     IPDGAKVGDTPAGIDKLKGTIQKVQTYAFQNPAGLDAEGGNLFKPSANSGDPQIAGAT
                     GTIIQGAIEASNVDIAEEFTEMIIASRSFQANSKIISTSDEILQEIINLKR"
     gene            9161..9364
                     /locus_tag="KRH23_002581"
     CDS             9161..9364
                     /locus_tag="KRH23_002581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar FlbD family protein"
                     /protein_id="HHS5225859.1"
                     /translation="MIRVTDLNGRKYILNSDLIVRIDSVPESRILLTTGEKNLVKESV
                     DEIVDKVIKYKRKINVGYIRSEK"
     gene            9364..10182
                     /locus_tag="KRH23_002582"
     CDS             9364..10182
                     /locus_tag="KRH23_002582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="motility protein A"
                     /protein_id="HHS5225860.1"
                     /translation="MKKTDSLTFIGLIVSTVLVLVGAAKGSSSGLKNFFDVSSILITV
                     LGSFGALMITFTIDDIKLIKNALQYSFKTMSVSKLDLLEQFKTLSKKARKEGLLSIES
                     DVMGIEDPFMKKGLELCIDGLEINEIRSILELEIDSVEDTNNRYSKLFKTWGTFAPAF
                     GMLGTLIGLIQMLSDLTSPDLIASGMGKALITTFYGSLLANIALNPIAYNIDEKTEKE
                     IYVKEMMLEGIISIQSGESSIVVEERLATYLSNNEKLEIMKSNKNTERAMSNGA"
     gene            10172..10867
                     /locus_tag="KRH23_002583"
     CDS             10172..10867
                     /locus_tag="KRH23_002583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family protein"
                     /protein_id="HHS5225861.1"
                     /translation="MARKKNKKKDEINPDAWLATYADTITLILTFFVLLYATSVVDME
                     KFKNIADALKGQFSGTSIFSTGSSTSEKSPIESVLVDKNDKSNLEQDLKDKVNNSNLQ
                     NSVTVKDDSRGILLELDDSILFDSGISELKADSKATLNKVYDMIKMMKNKIVIEGHTD
                     NVPVKSSTHESNWDLSSSRAVSVVRYFVEEKGMDPRLFSATGCGEYQPLVSNETAKGR
                     AENRRVNILITID"
     gene            10879..11316
                     /locus_tag="KRH23_002584"
     CDS             10879..11316
                     /locus_tag="KRH23_002584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009425 - bacterial-type flagellum basal
                     body [Evidence IEA];
                     GO_process: GO:0006935 - chemotaxis [Evidence IEA];
                     GO_process: GO:0071978 - bacterial-type
                     flagellum-dependent swarming motility [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body-associated FliL family
                     protein"
                     /protein_id="HHS5225862.1"
                     /translation="MFKNKKIIIIILILIIFSAGAGFFILGEGGNKQVDKIAGLFIPT
                     GKDEVKTENLDLEEMVLKLADEGVRYLKVSITVSYDSSYKDIEKNTPLIRDNIINCFM
                     AKRADDFTADNLKNIKEEIKNTLNIQLGENVIQNIYFTNIVVQ"
     gene            11331..11705
                     /locus_tag="KRH23_002585"
     CDS             11331..11705
                     /locus_tag="KRH23_002585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthetic protein FliO"
                     /protein_id="HHS5225863.1"
                     /translation="MILYLLKILICIPIILILIVLSLKISQGTLLKKYNDKYVKILDI
                     VNISKNNSIIILKIGEEGCIMASSSSSMNKIKDLTKEEILKIENDIKERNFKIQDFKM
                     ERIKKKYDFSRYIGKFTKKEDK"
     gene            11706..12371
                     /gene="fliP"
                     /locus_tag="KRH23_002586"
     CDS             11706..12371
                     /gene="fliP"
                     /locus_tag="KRH23_002586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425215.1"
                     /note="The bacterial flagellar biogenesis protein FliP
                     forms a type III secretion system (T3SS)-type pore
                     required for flagellar assembly; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar type III secretion system pore protein
                     FliP"
                     /protein_id="HHS5225864.1"
                     /translation="MELLSKLPLADVPYTSSMQLFLFLTALMFLPFVMFMMTSFVRIV
                     ISLSFLKSALGAQQAIPSQILVGLAIVLTIFIMRPVLNEINEKALQPYMKEEVTMEEA
                     MKEAEGPIKEFLLTQTRQTDLDLFVEQAGLKEKKLTRENIPLSVVVPAFAISELKTAF
                     QIGFLIYIPFLIIDLVVASVLMSMGMFMLPPVMISLPFKLLLFVMVDGWNLIVKTLIL
                     GFG"
     gene            12384..12653
                     /gene="fliQ"
                     /locus_tag="KRH23_002587"
     CDS             12384..12653
                     /gene="fliQ"
                     /locus_tag="KRH23_002587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0044780 - bacterial-type flagellum assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FliQ"
                     /protein_id="HHS5225865.1"
                     /translation="MSEFMIMSVLKNGMFTGAMIAAPVLIVSLVVGLLISVFQATTQI
                     QEQTLTFVPKLIAILLVVAIGGSWMLHTLISFTSEIFNMISLITK"
     gene            12665..14479
                     /locus_tag="KRH23_002588"
     CDS             12665..14479
                     /locus_tag="KRH23_002588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fused FliR family export protein/FlhB family
                     type III secretion system protein"
                     /protein_id="HHS5225866.1"
                     /translation="MIFVFIRIVAFFGTLRILFPAGTPALFKSLFAIIISILISSTMQ
                     IEYATNIDNIVLFTLYGVNETITGIMLGYITNLCFYSIRMAGSMMDQQMGLSMINMFD
                     PNSMTQTTLIDNLMNWTALMIFFSMDGHHVLIRGIRYSFELIPIGKPFVDNNIDYIIN
                     IFVQCFLTGFKIAIPIVLCLLMADFILGLISRSVPQLNVMIVGMPLKILVGIALFIIS
                     IPLIANQISHLLSQIPKMYEGTFALAPMFFMGSTDKTEEATPKKKGEQRKKGNIAKSR
                     ELPVAMTLLAFTLLVPTLFSYVVDTLKSSLNYFLSLDFYMNINYSNLEKLVIAGLMDF
                     FKIFLPIAIPFLVLGIIANLFQVGILFTGETLKPNLSKLNPVSGFKNMFSMRSLSTLI
                     KDIAIISILAYIGYTFFQDNYLDILKLGNIYLPTLMYTVKDLVYSILSKICVAMIAIA
                     VADYVYQRYSHKKQLRMTKQEVKDEYKNSEGDPEVKAKIKQKQRQISSQRTMQAVPSA
                     TVIVTNPTHLSIAVRYEKGKDQAPVVVAKGADYLAFKIREIAKGNDIPIIENKPIARL
                     LYKQVEIDQEIPEDMYQAFAEILVAVYKIKNRYKVPKR"
     gene            14488..16563
                     /gene="flhA"
                     /locus_tag="KRH23_002589"
     CDS             14488..16563
                     /gene="flhA"
                     /locus_tag="KRH23_002589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0044780 - bacterial-type flagellum assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FlhA"
                     /protein_id="HHS5225867.1"
                     /translation="MNKFNLKENMDVIVAFGVVGIVLMMIVPLPTFILDILLAINISL
                     SVLILLMTLFTTNVLDLSIFPTVLLVTTLFRLGLNLSSTRLILTQGYAGEVIEAFGSF
                     VVGGNYVVGIIIFLIILIVQFVVITNGSGRVSEVTARFTLDAMPGKQMSIDADLNAGV
                     IDDKTARKRRKELQQEADFYGSMDGANKFVKGDAIAGLIVTAINIIGGIVIGAVMLNM
                     TLMGAAQTYVRLTIGDGLVSQIPALLISTSAGIIVTRASTDENFGDLVGKQLTAIPKA
                     VMMTGCVLIVLGMMPGLPKPAFFSLGIGAIAAGYFLGREKKDTLEDLEFEKPDMVNPD
                     KNEVEDVTNLINVESIEVEIGYGLISLADESAGGDLLQRIASIRRQCAIDMGIVVQPI
                     RIRDNLQLNPNQYNIKIKGNVVGGYEIMPNMVLCMDPMNQGFSIFGIKTIEPTFGIEA
                     LWIESDKVEDAELKGYTVVDSSTILITHLLDIIKSNAHELLGRQEVKTIIDAARENYS
                     AVVDELIPDLMTLGEIQKVLKNLLREKVNIKDRVTILETLADQSRNTKDIELLTEYVR
                     IALARSICNNLVDDDKTIVVATLSPETEELISNNLQRSVNGTYPAVDPENTNKIFESI
                     QEVMSNVYFNHNIPVIVVSPKIRAPFRKLVEIVYPNLTVLSLNEIPNDIKIKAEGVVS
                     IYDDEKVYS"
     gene            16541..17554
                     /gene="flhF"
                     /locus_tag="KRH23_002590"
     CDS             16541..17554
                     /gene="flhF"
                     /locus_tag="KRH23_002590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012815985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0044781 - bacterial-type flagellum
                     organization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FlhF"
                     /protein_id="HHS5225868.1"
                     /translation="MTKKYTANTIQDAMNLAKMELGDNITLIDKKEVRKSGIQGIFSK
                     KDIELTIGWEKRENVEQKDLKREIEQLKLIINNMGFDNKNDNDIDKICKNLLSLELNE
                     EIVESIRIDLQEMKFNGIDTSKNLVEILKKKIKIENQVINGKIALVGPPGVGKTTTIA
                     KLAAKLVFEENKKVGVITIDTYRIGAVEQLKIYTDIMNIPFKGVISPDEMELALDEMK
                     DCDVVLIDTTGRGYKNSMQILEIKNLIDKAETDNIHLVLNCTTRESDTKAIIDSYRNV
                     NFKSLIITKLDETITYGSIFNIMNYAQKPISYITTGQNVPDDIIKPNEDKIIRLLLGV
                     ESI"
     gene            17551..18429
                     /locus_tag="KRH23_002591"
     CDS             17551..18429
                     /locus_tag="KRH23_002591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MinD/ParA family protein"
                     /protein_id="HHS5225869.1"
                     /translation="MIDQAQILRKMAMEKRGLDEFIVENENVPKIITIASGKGGVGKS
                     NLATNLSICLTKLNKKVLILDADIGMSNIDIIMGVNVKGTIIDVINGEKNIEDIISQT
                     KYGVNIISGGSALNHIEDFTEAQRNKFIHSIEQIHDVDFIIIDTGAGMSKSLLSFIYC
                     STEFFLITTPEPTSLTDAYSLLKAISNFGIKRSANIIINRVIDLEEAKSTYKRIKMVV
                     DKFLNLNLELYGYIIDDKKVSLCVKKQIPFILEYPTSIASKCIIAIAKRMVSQSREDI
                     VDNKSFLRKMFSIFKS"
     gene            18443..19144
                     /locus_tag="KRH23_002592"
     CDS             18443..19144
                     /locus_tag="KRH23_002592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed RNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HHS5225870.1"
                     /translation="MNREELIKENMPLVKSIARKFFIPGKGFEYQDLVNSGVIGLIDA
                     INKFDAEKGAKFSSYSYIKIKSAILDEIRNQSPISKHNLTKVNKYNRVVEKLQSKLLR
                     EPTSYEIAKELKVSEKELHDIESNIDMLNIVSLNYVIFEDTNETVQDVISDREEEAPE
                     NIIEEEEKLEILSKAISNLNEREKLILSLYYYEDLNLKEIGKVLGVSESRVSQLHRKS
                     IRNLRNKIKELKYSI"
     gene            19160..19582
                     /locus_tag="KRH23_002593"
     CDS             19160..19582
                     /locus_tag="KRH23_002593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein"
                     /protein_id="HHS5225871.1"
                     /translation="MIQIILIVVSILIIVTIVINLHKESKNKDNRYFDKIFEQEYEAN
                     DRLIIAEKRRFFLDKVLAEKRSNSHIKVYENYNLIKANEERKENIFIESKKEVRQENE
                     LSLKVKHLISSGYDDVEICKMLDIGKGELLLIRSCYKI"
     gene            19567..19752
                     /locus_tag="KRH23_002594"
     CDS             19567..19752
                     /locus_tag="KRH23_002594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein"
                     /protein_id="HHS5225872.1"
                     /translation="MLQNIRILLCDKKVFLGIGIGILISTLCIMLFSNNDMSKAEIEK
                     KARALGMKYTSEMKVLE"
     gene            19793..20566
                     /locus_tag="KRH23_002595"
     CDS             19793..20566
                     /locus_tag="KRH23_002595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0071973 - bacterial-type
                     flagellum-dependent cell motility [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal-body rod protein FlgG"
                     /protein_id="HHS5225873.1"
                     /translation="MIRGLYTAVSAMITNQQKQNVVVNNLANMDTNGYKSKQLLTKSF
                     DELKLEGYNNYANGTKQKQIIGDISPGISMDETITNFNQGPIKTTDNKMDVAIQGKGF
                     FLVSDAAGNQFYTRNGNFRTDNQGDLITSEGYYVLGTNTATGAVGHINVGNQKFEVAK
                     DNTISLDGNAMYKFNIVDFNNYNNLKKEGDNLYSGGGAMKVNNALTIQSAIESSNVDM
                     VSEINNMMTISREYEANQKIIQAMDSKLAKIASEIGSVR"
     gene            20587..21348
                     /locus_tag="KRH23_002596"
     CDS             20587..21348
                     /locus_tag="KRH23_002596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-basal body complex protein"
                     /protein_id="HHS5225874.1"
                     /translation="MYTMFYTSKTALSANQSKLDIISNNIANSDSTGYKKINMEYSDL
                     VDEVLNRPSYPTNGNDISTGTGAKATAPMRNYEQGALAPTDSKSNLAIDGEGFFRVIR
                     KDGTYAYTRNGGFNVDALGKIVDDNGNILDVQFDAGYNYNNTNIDSTNLTVSRNGELF
                     VDNKKIGKINLYQPIGTQNFISEGDSLFVATDAAQIKQVEKVDIVQGYRERSNVSLQE
                     EFVDLIATQRAFQMNSKGIKTADEMWQIANNLRAK"
     gene            21371..22252
                     /locus_tag="KRH23_002597"
     CDS             21371..22252
                     /locus_tag="KRH23_002597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliM/FliN family flagellar motor switch protein"
                     /protein_id="HHS5225875.1"
                     /translation="MNDMKEYDFGKPQSYSRENLTCLNFLLAEFCKKYKNYIIYELKC
                     NSSMVVDSIDQVNYQTFLDRVTSSCVVVQNAMEPVMKNFSFRIDRSVADMWIDITSGG
                     TGVVKDNDRELTELDKKVLLHLMDDLVRNMHLFEGFENIQVLDTHTHINLPQLCSPTA
                     PVCVVDLKVLNDNECIGSVSLCFPYNGLEALLESISVIEFFDNDVGDDSEEFTKKIYN
                     SVSNIELSVIAEIGKVSINVEDLLKLEVGDVIVTNKKINDYIDIFVENSKSYTATPGF
                     ISSKKGVKINDAVGKEV"
     gene            22255..22629
                     /locus_tag="KRH23_002598"
     CDS             22255..22629
                     /locus_tag="KRH23_002598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliM/FliN family flagellar motor switch protein"
                     /protein_id="HHS5225876.1"
                     /translation="MDNSNLISDEEAKMLLNDKVESEVDGDDELALDVSEVNRNNIQR
                     ILDLKLELSVVIGRTKMTLRDILNLHKGSLIELDTLADQDVEILIDNKVLAYGKVVVV
                     DLNFGVKITSIVSEEDMVKSLV"
     gene            22661..24064
                     /locus_tag="KRH23_002599"
     CDS             22661..24064
                     /locus_tag="KRH23_002599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HHS5225877.1"
                     /translation="MVLILNLNDIKKDILKLNKKDSCSLYNESINNINNNCISTGLKF
                     LKQARDLNPDDVDILNLTGLVNLLKCNFDDAVESFYKSSLCEKTALCEKYINMLTSEE
                     FLIFFEKYNQLIRLINKGMYKEAIQGFKLITDQYCDLIEPYELLALLYDKEEEYIKFD
                     ECLEVLKIIDKENYLLNQENNTLDMYNSANIQTKSNIKVDDYKNEFLHKSSSNHKIND
                     YNNVTKEKSSSKNQKSSDSNKKKSIKKNKYLYIAIILGILLVGQSIYSSYKMNNLTDK
                     ISKNNETKNEESIDSNLTKKENNIEENEDMSKASNINKSNKNINKEDDVKSKKNTVKN
                     EDDKDSDLFTEDELMSKANTLKSEKKTKSSIQLYKKVADIGENKGNTSEATYQVAILS
                     EKLKDYKTAEEYYKMYVENYSEKDAYFDESYYNLGMMYYNNGDLKNSKLTLKKLVNKV
                     PNSMYNNSKVKEILKEE"
     gene            24180..26117
                     /gene="htpG"
                     /locus_tag="KRH23_002600"
     CDS             24180..26117
                     /gene="htpG"
                     /locus_tag="KRH23_002600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone HtpG"
                     /protein_id="HHS5225878.1"
                     /translation="MEFEKGSISIHTENIFPIIKKWLYSDKDIFIRELISNGCDAVSK
                     HKRLVSLGEISENKSSDYKITVSVNKGEGTLKFIDNGIGMTEEEIKKYINQVAFSGAE
                     DFFNKYKDKMEESNDIIGHFGLGFYSAFMVSKKVQIDTLSYTEGATPVRWISEGGTEY
                     EISESDTRNDRGTTITLFIDDDSKEFLDEFTVRGIINKYCSFLPVEIYLEDVERLERE
                     AKEVEEKAKKQKEDGKEEVVDAKIIEPLNDTNPLWLKSPKDCTDEEYKEFYRKVFNVF
                     DEPLFWIHLNVDYPFNLKGILYFPKLKNEFELTEGKVKLYNNQVFVADNIKEVIPEFL
                     LLLKGVIDCPDLPLNVSRSFLQNDRDVSKISKHIIKKVADKLKSLCKNEREEYNKFWD
                     DIQIFIKYGCLKDESFYEKVKECILFKTIDDEYITLQDYLEKCKDKHENKVFYVSDKE
                     QQSQYIKLFKEYDLSAVVLNSSIDTHFISFMEYKENGVKFNRIDADLSDVLKDKNENK
                     DSEENKEEIAKIEGLFKEAVGERVKNYSVEGLKNEDTPAMVLVSEQSIRMAEMQSRFA
                     GMDLGMNFEEEKTLVINENSPIIKKLVSLKDDEEKKDKITLICNQIADLALLSNKELK
                     PDELDSFVQRSNKLMSLLIEL"
     gene            26505..27635
                     /locus_tag="KRH23_002601"
     CDS             26505..27635
                     /locus_tag="KRH23_002601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HHS5225879.1"
                     /translation="MNFNYNLPVNILFGRGRINDVGKEVSKYGKKVLIVTGKNSTKKT
                     GLLDKTIDLLKDSKIEYKVFDRVEQNPLITTIYSGVEIIKSTGCDCVLGLGGGSIMDA
                     AKSIAFSYKNPGDLNDYIFGIRQGEEALPIILVPTTSGTGSEGNCFAVLTNSETKDKK
                     SIKKNSMYAKASIIDPELMVTMPKHIIASVGFDALAHNMEAYLSNGRNPLADVQAIYG
                     IELISENLIKVYNDVNDLEAWEKITLASTIGGMTIGTAGTALPHGMEHPVSGLRDVMH
                     GKGLAALTPTIIESSWDSDIERFGNISKVLGGTCAEDCSDAIRNFLKKIDLDIKLSDL
                     GIEKSDIDWLTDNCMKISVANIKRHPKYFNKEQIKEMYHKSL"
     gene            27862..28884
                     /gene="splB"
                     /locus_tag="KRH23_002602"
     CDS             27862..28884
                     /gene="splB"
                     /locus_tag="KRH23_002602"
                     /EC_number="4.1.99.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016830 - carbon-carbon lyase activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0006290 - pyrimidine dimer repair [Evidence
                     IEA];
                     GO_process: GO:0046500 - S-adenosylmethionine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="spore photoproduct lyase"
                     /protein_id="HHS5225880.1"
                     /translation="MFNPKRIIFEKGTLDTDVGKKIYNKFRDNKDVEIINISSNRIKE
                     HIPGENLYEQYRSGKQTMVVGIRKSLKFQTCKPSANYQLPLVSGCMGRCEYCYLNTQL
                     GDKPFIRVFVNVDEILEQTKKYIEDRKPQVTIFEGAATSDPVPVEPYTNSLKKTIEFF
                     GREEKGRFRFVTKYSDVDSLLDAEHNNHTEIRFSINTPRIINEHEHYTASANKRIESA
                     VKLARAGYQIGFIIAPVFLYEGWKEEYKNLIISIKEALPKDFDKKIIFEVISHRYTTK
                     AKNRILEIYPDTLLPMENEDRKFKYGQFGYGKYVYDKEQLDDMKEFFLKEINGVFKNS
                     LIKYII"
     gene            29066..29977
                     /locus_tag="KRH23_002603"
     CDS             29066..29977
                     /locus_tag="KRH23_002603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HHS5225881.1"
                     /translation="MHAWESIQITLDLIEANLSEEISINELANKANLSPFYYQRLFKR
                     LVNKTVMEYIKLRRLARASEYLAEHKNRILDVALNFGFASHETFTRSFKKAYGLTPEK
                     YRANPVKLNHFIKPELILNYAMVDEGVPLIADDIVIEVNRKTLSNPRTFVGIEIEVPI
                     CQLVGGETTGIAIVEELWMKLGSQRHNIPNQIPGGNEFAALYMGNAKEGNCMYMAGVE
                     VESGTSVEGYSTFELPAKEYLVCGFEAENFNELVNSAVFKADKFMERWMKKHNLTTTD
                     FAIEMYYPTTPEAAYLEHWIVPVPIEQ"
     gene            29992..30408
                     /locus_tag="KRH23_002604"
     CDS             29992..30408
                     /locus_tag="KRH23_002604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3788 domain-containing protein"
                     /protein_id="HHS5225882.1"
                     /translation="MNWQDAFFQDTKPTFEQINEFINNPLWDKLNKTLVSTYNVEPKL
                     EYSKCSMQRGWNVKYKKRGKSLCTLYPQEGYFKALVIVSESNRVEVDLFINTCCDYIK
                     KIYNEVNFFNGSKWLMIQVDSLLVLNDMLELIKFRA"
     gene            complement(30508..30900)
                     /locus_tag="KRH23_002605"
     CDS             complement(30508..30900)
                     /locus_tag="KRH23_002605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HHS5225883.1"
                     /translation="MSINTEKNITKNVEELTCPIRYALDIVGGKWKLPIICMLAVENP
                     IRYSSIKRKLDGITNTMLAQSLKDLESTGIVHRKQYNEIPPKVEYTLTSKGKSIVPIL
                     QQFANWGATNMQEKNTCGLSCKECRKIK"
     gene            31041..31436
                     /locus_tag="KRH23_002606"
     CDS             31041..31436
                     /locus_tag="KRH23_002606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HHS5225884.1"
                     /translation="MKALEFLNKAGVYYLATVDENNQAHVRPLGFVMEYNGKLTFCTS
                     NQKDMFKQLIFNPKVELCCIDQNLNTLRILGEAVFVTSKETQAKALEIMPSLGQMYSV
                     GDGKFEIFSIDKAKVSCCSMSGKKIDVEL"
     gene            31838..32044
                     /locus_tag="KRH23_002607"
     CDS             31838..32044
                     /locus_tag="KRH23_002607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5225885.1"
                     /translation="MSKYSSLWEYVKKNNSQSFKLTFEEIKDIAGIEIDHSFLKYKKE
                     LNEYGYQVGKISLKEKTVIFDKIG"
     gene            complement(32201..32932)
                     /locus_tag="KRH23_002608"
     CDS             complement(32201..32932)
                     /locus_tag="KRH23_002608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5225886.1"
                     /translation="MLSKKNVSLIILVIILSLLTAIFIFNNKNTNNKLKEVTKNNEEI
                     VPKNLEGLSIEQLIEIRDKAIDKNLEGLREFGEDSVKKRKDSILNFEFGLVAFVNKNY
                     SNLTEKEKLIRQINIVNYENSINDIMDPSGSFFELANQNYQVNEFLLKNGKDYKEWSY
                     EGLDFLIDHLEELCKFVDFDVKDVIDIIDPTIKTDLSEEQKKSLNDKLKKISSSDTLS
                     EEVKKEIKNWENNLNNLNMNKNNSN"
BASE COUNT        13476 a         3515 c         6001 g        10092 t
ORIGIN      
        1 aagcaaaata aataaaatat attttgagga ggagtgagtg tgaatacata tgacattata
       61 aaaatgggat tagatgcaac taatttaaga agtcagacaa tagcaaataa tatagcaaat
      121 ataaatactg aaggatataa gagacattat gtaacttttg aagaaacact aaatgatgct
      181 atgcccaaaa tagaagaaaa aacagataat tctaaaggat taagagtgga tggcaataat
      241 gtagatatag aagaagaaaa agtaaaccaa gcaatgacaa cattacaata taatgctttg
      301 ataagttttg caaatggaaa aatagcaatg actaaatcaa taataagtgg gaggtaatta
      361 gaagatgagt gtgttcagtg gaatgagaat atctgctagt ggattaacag cagaaagttt
      421 gaaaatggat atcatatcat ccaatgtagc taatataaat gctacaagag gtccaaatgg
      481 agaagcatat aggagaaaag ttgtttcatt tgaagaaaac tatgataata aattaggtat
      541 gctaggagta aaagttacat ctgttgaaga tgataaatca cctcttaaag aagtatatga
      601 cccatctcat ccagatgcaa agccaaatgg atatgtagaa tatccaaatg taaatatatt
      661 ggtagaaatg acagatttaa taacagcttc acgagcatat gattctaacg tagatacatt
      721 gaatgctcag aagtctatga tatcaaaagc tttggaaata ggaaagtagg gataaattat
      781 gccaattaca caaattaaca atttaatgca aggtgcaaag ttagataatt tgattggaga
      841 agcaaagcca ttaactctta ataataaaga agaaaaaaag aattttgaag atgtaataat
      901 agatactata gataaagtta attttcaaca agtaacagca gatgatatga aagaaaaatt
      961 tataaaaggc gaagatgttt ctatgcatga agttatgtta ataggtcaag aagcacaact
     1021 atctatgcaa tatttaatag aagttagaaa taagattcat gatgcatatc aagaaatgaa
     1081 taaggtgcaa atttagcctt ttgaacagga gtaataatca atgataacca gttttaaaaa
     1141 taagattaag gagcaagttg ctaaatctag gacaaagata agttctttaa aaaagggaac
     1201 taaaatagca ttaggtatag gggttattgc tatatgttta gcgctagtat ttacagcaat
     1261 atctgcgagc aaaaataagt atgcagtctt attttcagaa ctagatgctc aagatgctgc
     1321 agatatatca gcagagctag agtctaaaaa gatagatact aaggtaaaag gaagtacgat
     1381 ttatgtacct agaacagaag ttgataagtt aaggctggag ttagcgccaa gtcttacagg
     1441 tggttctaaa ggatttgcac taatggatga tagttcatca atagggctta ctgatgaaga
     1501 atttcagatt aagaaacaaa gaatgataca aggtgaaata gaaaaaacaa taaagagttt
     1561 tccacaagtg gaagacacta gagtacatat aacatttgga gagtcatcag tatttgagaa
     1621 ggaggctgtt ccagggagtg cagcagttta tttgatgcta aaaccaggga cgactttaga
     1681 aaaaaaccaa ataaagtctg ttatggcact tatatcagga agcgttacaa atataccaga
     1741 gaaaaatgtt caggttattg ataacaaaat gaatttatta tctgaaggta ttttggagga
     1801 tgaaaatgtt gatgaaaata atcaaccaat aaatagtggc attagtgtcg ataaaaataa
     1861 ggcatctgaa caagcattga ataaacaact agaaaagtct attttagaaa tgctagaacc
     1921 gatatttggt aagggaaagg tgaaagctac agtaaatgct gatttaagtt ttgatacagc
     1981 tgaaaaaact gagataaaaa ttgaccctga taaagttgca ataaaggaga caaggtcgaa
     2041 aaattcatct aaatctgctg caaataatgt tcaaggtgta gatgctaaca tgaataacca
     2101 aggaaataac aatggtacta atacagaaga tagtttagat gagagttttg agtatgaaac
     2161 aggtaagatt gaaactcaca ctatagttgc gcctggagaa cttaatagat tgacagcttc
     2221 tgttgcaata gatggaaaaa tagctaaagg tgttcaagct gatgtagagg atattgttaa
     2281 taatgctata ggtatggatg gagcgagggg agatactctt agcgttgttt caatggtatt
     2341 tgacccagaa ggtaagaaag aggctaaaca agagctggaa gagattaaaa aagaaggatt
     2401 taaaaagaac ataataaaag cagttattgg agtagtagca gtaatagcag ttggagctat
     2461 tggatactta atatataaga aaagaagtga acgagaagat atggattatg aagatgaaga
     2521 ttatatttct aaatctgatt ctgttgataa gaaggataat cctctattag gagatgatcc
     2581 agaactgaca ttagaggaag ctgttaaaat gtatgcagaa gaaaagccag accaagtaac
     2641 agagataata aaaacttggt taaatgagta agggggatag aaagtgtcca cagaaattac
     2701 aaatgttaat gcgtttgact taagtgatat aagtgaaagt gataagaacg agaaaataga
     2761 aggtgaaggt ttaaaaaaag ctgctgtatt attaatgaca ttagggccag atgtctctag
     2821 cgatataata aaaagtttgc ctgataaaca agttcaaaaa ataggtttgg aaattgcaaa
     2881 tatttcttca atagcttcaa aagaaagaag agaaatctta aaagagtttg tagaaataaa
     2941 tagggcaaaa gattatgtta tagaaggtgg gcttgaatat gcaagagagt tgttaagcaa
     3001 tgctttagga aatgctaaag caaacaaatt acttgaaggt atatcaataa atacaagtac
     3061 aaagcctttt aaacatatta taaaactaga tgtaaagaag atattagaaa tacttaggaa
     3121 tgaaagtgca caaactatag ccgttttact tgcacatatg gagccagaaa atggagcaga
     3181 agttttatca tacttagatt ttgatttaca aaatgaagta gctatgagaa taagctcaat
     3241 gggttcaata tctccagaag taataaaggt aattgaaagt tcattagaag ataaattaca
     3301 ttcaataagt ggtgatgatt ttaatgatta tggaggggtg tctaccttag ttcaaatatt
     3361 gattaattct gatagaaaaa cagaaaagaa tattttggga actattgaag aacaaaaccc
     3421 ggatttagca gctcaaatta aatctcatat atttgtcttt gaagatattg tcaagttaga
     3481 tgatataagc atacaaaaag tgttaaaaga agtgactatg aaagatttag tatatgcctt
     3541 aaaaggtgta gatgatgaga tttcagatgc tatatataga aatcaatctt ctagggcagc
     3601 agatgcactt aaagaagaaa tggaaatggt tggtgttata aaggttacac aagttgaggc
     3661 ttctcaacaa aagatagcta atatcgtaag aaaacttgaa agagaaggtg ccataactat
     3721 tgtaaggaat tttggtggtg actttgttga ataataagat tattaaaagt aaaaaagcat
     3781 tatataaagg agtgctagat ttaaccataa tagataaagt tagagtggga gaatcaaatg
     3841 taaataaaga aaatgattgt agatttaggg atgaggtaat aaaagaagct atagaatctg
     3901 ctgagataaa aaagaatgag atattagaag aagcaaaaat aaatgcacaa aatatagaaa
     3961 agcaagcata tgaaaaaggg tatagtcaag gtcaaaaaaa tggatatgag gatggatata
     4021 aagagtcata tgatgaatat acccaaaaag ctaaagatga agcagatttt ataaaaaatc
     4081 aggcaaattt aatcttatta caagctaatg agaagatgac tgagtacata aaagaaaaaa
     4141 ataaagagat tgtaagactt gctattaata tggccagttc tgttttaaaa aagcatttcg
     4201 aagatgaaga atctatgagt gatttgttaa agcaaattat tcaagattat gaaggaaata
     4261 gttcatttat agtaagatgt aattctttct ataaagataa tatagagaaa gagtttgaat
     4321 tattcaaaga ggaaacatca ctaaaatcaa gtgtatttgt tattgcagat gatagtatag
     4381 ataaaggcaa tgctattatc caaaaggaaa atggaagaat aatagttggt attgattgtg
     4441 ctatggaaaa actaaaagaa gaattgcttg gtgaataaag tatgtataaa actgatatat
     4501 ctatagattt tgacaaaata aataagaaaa tagaaaattt agaactcact atatcagaag
     4561 gtagagtaaa gaagataata ggacttactg tagaagttga aggaataaaa gcttttgttg
     4621 gggagttatg cgttatatac aaccaagtta ataaaccagt gaattgtgaa gtagtaggtt
     4681 ttaaagataa agaagtcata ttaatggcgt tgggagaatt aacattgata gcacctggtt
     4741 gtaaagttat ttctaagggg atacctttaa gtgttatgtg tagtgataat ttactaggta
     4801 aagtacttga tggtcttgga aatcctatag ataactcaga tgctgtttta ggagatagat
     4861 acaacctgaa caatgaacct cctgacccaa tgaagagaaa aaagatacga aatataatgg
     4921 aaacaggtgt aagagcaata gatgcattta ctacttgtgg tgaaggacag agaatcggca
     4981 tatttgcagg aagtggagta ggtaagagta cgactctagg tatgattgct aggaatgcaa
     5041 aagcagatgt aaatgtaatt gctcttattg gagaaagagg aagagaagta ctagatttta
     5101 ttgataaaga tttaggtgaa gagggaatga aaaaatctgt tgttgtgtgt gcaacatcag
     5161 ataaagcccc tctagttagg ttaaaaggtg ctcttactgc tactgcaata gcagaatatt
     5221 ttagagacca aggcaaaaaa gtaatactta tgatggattc agtaactaga tttgctatgg
     5281 cacaaagaga agttggtgta gcaataggag agccaccagc tcaaaaagga tatacaccat
     5341 ctgtatttgc aatgttgcca aaacttatgg agagaacagg gacatcagat aaaggttcta
     5401 taactgcatt ttatacagta ttagttgatg gagatgactt taatgagcca atagcagata
     5461 caacaagagg gatacttgat ggtcatatag ttttatctag agacttggca aataagaatc
     5521 actatccttc tatagatgta ttaaacagtt taagtaggct tatgaatgaa attgcttcaa
     5581 aagaagacat aaaaatagcg tcttttgcaa gagacatgct tgctgagtat agagaagcag
     5641 aagatttgat aaatataggt gcatatgctt caggtacaaa taaaaaaata gatgaagcaa
     5701 tctattatca tgagcatatt attaattttt taaaacaagg gataaatgaa aagagttctt
     5761 ttaatgaaac tataagtagt ttgagaagag tttttgaata aacaattaaa aaaatatttg
     5821 aataggttgt gatggaattg gataaaaact ttaagtttag attacagaaa gttttagact
     5881 taaaagtgaa agatgaagaa gagataaaaa tggaatttgc taagattcaa caaaaaaaaa
     5941 tagatataga gactaattta gaaaacttag aaagtaatta tagcaaatat tctataagta
     6001 aaaataacga tagtattcaa aatcaaaaaa taactattaa ctatttacta gctttaaaca
     6061 attctataat ggatttatca gaagagttgg ataagtcaac aaatgaactt gaaaaagcta
     6121 gaaagcagct tataagcaaa cagatagaga gaaaatcatt agaaaaatta aaagaaaaaa
     6181 agtatggaca gtattataaa gaagaaaatt taaaagaaca aaacactaat gatgagtttg
     6241 caagtatgag ttatttaagg aatagacaag ttctataaga atagtaggaa gtgaggatat
     6301 tattgtatga agatacaagc agattcttat aatattatta aagatattgg ggatagaaaa
     6361 agttcatcta agaacaaaaa tataaaaaat aataaatttg aagataatct atataaggca
     6421 acagaccata aaaaggttaa agatagaagg gaagtaagta agcaaaatat tagctcagat
     6481 aaaccggaaa atagtgataa tgagtgtcat ttagatgaag ataaaagtaa tcacttagaa
     6541 gatgaaaata catatgaaaa agattgtagt aagaataatg aagctttgca gcaattactg
     6601 aatcttttaa aggataatta taaaaaagat aaagatataa acactatatt ggataatata
     6661 gaaaaactaa gtatatcaga tgaattaaaa caagaactta agcttaataa aaatatatta
     6721 aacaagattg caaatcaaaa ttcagagcta aataaagcta atataaataa ctctaatgat
     6781 atagaaaatt tagacatagt taaattaaga gaacttttgg aagatagtgc taataaagat
     6841 attgaagtaa ttagtaaaac tacagaaaat gatactaaaa atatagattt gtatagtttt
     6901 gatagcaata gaatggataa tcttaactca aataaacaga aagatgatag ctctgatatt
     6961 ttggaaaaac tagcaggggt aaatggaaat aagagtggga attttggaca agtaataaat
     7021 aaaaatgttg atatgaacaa acttaaaaat gataatgtca atttaaaaca gatagaatca
     7081 aatgtaatgg atgactctat aaaagctatt aagcatatga aaacaaatga tatacaagaa
     7141 ttgacaatta aattaagacc aaaagaatta ggagatatga atatacaatt gttaaaagat
     7201 ggtgaaagta tgagagctgt tgtgactgtt ttcaataaag atgtctttga ctctataaat
     7261 aaaaacatat cagatttaaa gcaacatctt gaacttacta atgtaaatat aaaagatgta
     7321 tcagtgcaaa tgcacagcga taatacaaat acatctgata cctttgataa agcatttgaa
     7381 caacagaata gacaaaataa ccaagaaaac atgagtaaga agaatacaaa tgataagcat
     7441 aataatgtag tcatagaaga tgacattaaa gaaaatatta ttgatgatga tagagtagat
     7501 ttactagctt agtaaggggg aagtattgca tgtacggaat agcaacggct ttggcaggaa
     7561 ctcagggaaa ctataggtca aataacttaa gccaacttga aagaaatatt aatgatattg
     7621 ccaataaaca agttagaagc aaaggaaatc agacagtaac agacaatggg actccaatta
     7681 taggacaagg tgatgatgct gataaagact tgtttatgaa gatacttgtg gcacagatgg
     7741 gtaatcaaga cccaatgaat ccgcaagacc caacagaata tgtgtcacaa ttagcacagt
     7801 ttgcaacttt agaaaagatg tcagctatga atgagaagct agatgtactt ttagccttaa
     7861 gtaattctac tctaataaac tctgctttga gtatggcaac atcattaatt ggtaaagaag
     7921 tagaagtatc tggggaagag aaagaagatg aaaatattgt aggagtagta aagtccacat
     7981 atataaaaga tggggaagta cacttagaat tagaagtaga tggaagtgac aaaactgtag
     8041 gtgttaaata tgaaaaatta cttaaaatag gagaggtaga tgaaaattca ggagaagaaa
     8101 atgactcttc agaacacgaa tctccagaag aagcataata ttaaatgaga aaagaggtaa
     8161 attcatgata aaagcaatgt attcaggtgt aagtggaatg aaagcaaatc aaacaaaatt
     8221 agatgtaata ggtaacaatg tagccaacgc tggaactact tcttttaaga aaagttcagc
     8281 tagaataaca gattcatttt atcaaactgt actatatgca agtgctccaa cagctgcatt
     8341 aggaggaaca aacttaggac aagtaggtgt aggtagtaag atatcaagta taaataaaga
     8401 tatggtacaa ggaaatgtac aaccaactaa tagaccatct gatttaatga tagatggaga
     8461 tggatatctt ccagtagtaa gacaaggaac agttatgtat acgagagatg gttcttttaa
     8521 tttagataca ggatttaaag cagctgatgg tgctttgaag aatattaaag gtggaagact
     8581 tgtaaatggt gatggatata tgttacaagg tatgatttat gatggggaat ataaagctga
     8641 tactggagaa tttgttaaaa agggtgatgc taaaggaaaa gagcctattg taataccact
     8701 tcaaagtata agtcctaagg atggaacagt tcaaaatgta ctagagtata atatatcaaa
     8761 ggatggaaca gtagaatttt tattgagtga tggtcaaaga actcaatttg tctatgatat
     8821 acctgatggt gctaaggtag gagatacacc tgctggaata gataaattaa aaggtacaat
     8881 acaaaaagtg caaacatatg cattccaaaa tccagcagga ctagatgcag aaggaggaaa
     8941 cttgtttaaa ccatcagcaa actcaggaga cccacaaata gcaggagcta caggaacaat
     9001 aatacaaggg gcaatagaag cttccaatgt agatatagca gaagaattta cagaaatgat
     9061 aatagcaagt agatctttcc aagcaaacag taaaataata tcgacatcag acgagatact
     9121 tcaagaaata ataaatctta agagatagta ggtacatatt atgataagag taacggattt
     9181 aaacggaaga aaatacatat taaattcaga ccttatagtg aggattgatt ctgtaccaga
     9241 aagtaggatt cttcttacaa caggagaaaa aaaccttgta aaagagtcgg tagatgagat
     9301 agtagataaa gtaataaagt ataaaagaaa aataaatgta ggttatatta ggagcgaaaa
     9361 ataatgaaaa aaacagattc actgacattt attggactaa tagtatctac agtattagtt
     9421 ttagttggtg ccgcaaaagg aagtagttca gggttaaaga atttttttga tgtttcatca
     9481 atattaatca cagtgcttgg ttcatttgga gctctaatga ttacatttac tatagatgat
     9541 ataaaactta taaaaaatgc attacaatac tcatttaaga caatgagtgt atcaaagtta
     9601 gatttactag aacaatttaa aacactttct aaaaaagcta gaaaagaagg tcttttatca
     9661 atagaaagtg atgtaatggg aatagaagat ccatttatga agaaagggtt agagctgtgt
     9721 attgatggat tggaaatcaa tgagataagg tctatcttag aactagagat agattctgtt
     9781 gaagatacaa ataacagata ctctaaacta tttaaaactt ggggaacctt tgcacctgct
     9841 tttgggatgt tgggaactct aataggttta atacaaatgc tatctgacct tacatctcca
     9901 gatttaatag catctggtat gggaaaggca ttaattacaa cgttttatgg ttctttactt
     9961 gctaatatcg ctttgaaccc aattgcatat aatatagatg agaagactga aaaagaaatt
    10021 tatgtaaagg aaatgatgct tgaaggtata ataagcatac aatctgggga gagcagtata
    10081 gtagttgagg aacgtttagc cacatacctt tcaaataatg agaagttaga aattatgaaa
    10141 tccaataaaa atacagaaag agcaatgagc aatggcgcgt aaaaaaaata agaaaaagga
    10201 tgagataaat ccagatgcat ggctggctac ttatgcagat acgataacac tgattcttac
    10261 atttttcgta ttattgtatg caacatcagt tgtagatatg gaaaaattta aaaacatagc
    10321 agatgcgtta aaaggtcagt tttctgggac aagtatattt agtacaggtt caagtacaag
    10381 tgagaagtct ccaatagaga gtgttttagt ggataaaaat gataagtcaa atttagaaca
    10441 ggatttaaaa gataaagtta ataattctaa cttacaaaat agtgtaacag tcaaagatga
    10501 tagtagaggg attttactag aactagatga ttcaatttta tttgactctg ggatttctga
    10561 attaaaagca gatagtaaag ccactcttaa taaagtatat gacatgataa agatgatgaa
    10621 aaataagata gttatagaag gccatactga taatgtacct gtaaaatcaa gtacacatga
    10681 atccaattgg gatttatctt ctagtagagc agtaagtgtt gtaagatact ttgtagaaga
    10741 aaagggcatg gaccctagac tattttcggc aacaggatgt ggagagtatc aacctttggt
    10801 ttcaaatgaa acagcaaagg gaagggctga gaatagaaga gttaatatac ttataactat
    10861 tgactaggag gaagaggttt gttcaaaaat aaaaagatta ttataattat tttgatactg
    10921 attattttct cagcgggagc aggttttttt atattaggag aaggtggaaa taaacaagtt
    10981 gacaagattg caggtttgtt tattccaaca ggtaaagatg aagtaaagac cgaaaatctt
    11041 gacttagaag agatggtatt aaagctagct gatgaaggtg taagatattt aaaagtatca
    11101 ataactgtat cttatgattc ttcatataaa gatatagaaa aaaatacgcc tttaattagg
    11161 gataatatta taaattgttt tatggcaaaa agggcagatg attttactgc tgataattta
    11221 aagaacataa aagaagaaat taaaaataca ttaaatatac aactaggtga aaatgtaatt
    11281 caaaatatat atttcacaaa tatagtagtg caataaaagg atggtaagac atgatacttt
    11341 atttactaaa aatattaata tgtatcccaa taattttaat attgatagtc ttatctttaa
    11401 aaattagcca aggaacttta ttaaaaaaat ataatgataa atatgtaaaa atattagata
    11461 ttgtaaatat aagtaaaaac aatagcataa taattttaaa aataggtgaa gaaggatgca
    11521 ttatggcatc ttcttcctct agtatgaata aaataaaaga tttgaccaaa gaagaaatat
    11581 taaaaataga aaacgacatt aaggaaagaa attttaaaat tcaagatttt aaaatggaaa
    11641 gaattaaaaa gaaatatgat ttcagtagat atattggaaa atttacaaaa aaggaagata
    11701 agtaaatgga actattatca aaattacctt tggctgatgt accatataca agttcaatgc
    11761 aattgttttt atttctaact gcattaatgt ttttaccatt tgtaatgttc atgatgacaa
    11821 gctttgtcag aatagttata agtttatcat ttttgaaatc agcgttagga gcacagcaag
    11881 caattccaag tcaaattttg gtaggacttg caatagtatt gacaatattt ataatgagac
    11941 cagtattaaa tgagataaac gaaaaggcat tacaaccata tatgaaagaa gaagttacta
    12001 tggaagaagc tatgaaggaa gcagaaggac ctattaaaga gtttttatta acacaaacca
    12061 gacagacaga tttagattta tttgtagaac aggctggttt aaaagaaaag aaattaactc
    12121 gtgaaaatat accactatct gttgtagttc cagcatttgc tataagcgaa ctaaaaactg
    12181 cttttcaaat aggtttttta atatatatac catttttgat aatagacctt gttgtggcaa
    12241 gtgttttgat gtctatgggt atgtttatgt tgcctccagt catgatatca ttaccattta
    12301 agttattgtt atttgtaatg gtggatggat ggaacttgat agtaaaaaca ttgatattgg
    12361 gatttggata ggagaaaaat agtatgagtg aatttatgat aatgagtgtt cttaaaaatg
    12421 gcatgtttac aggagctatg attgcagctc cagtactcat tgtttctctt gtagttgggc
    12481 ttttaataag tgtgtttcaa gctacaactc aaatccagga gcaaactttg acttttgtac
    12541 caaaactaat agctattctt ttagtagtag ctattggtgg aagctggatg ttacatactc
    12601 ttattagctt tacttctgag atattcaata tgatatctct tataactaaa taagtaggat
    12661 acatatgatt tttgtattta ttagaatagt agcattcttt ggaacactaa gaatactatt
    12721 tccagctggt acacctgctt tatttaagtc actctttgca atcattatat caatattgat
    12781 ttcaagtact atgcaaattg aatatgcaac aaatatagac aacattgtat tgtttacctt
    12841 atatggtgta aatgagacca taactgggat tatgcttgga tatataacca acctatgttt
    12901 ttatagtatc agaatggcgg gttctatgat ggaccaacag atgggattat caatgattaa
    12961 tatgtttgac ccaaattcaa tgactcagac aactttaatt gataatctta tgaactggac
    13021 agcacttatg atatttttta gcatggatgg tcatcatgtt ttaattagag gtataaggta
    13081 tagttttgag ttaattccaa taggaaaacc atttgtagat aataacatag attatataat
    13141 aaacatattt gtgcagtgct ttttaactgg attcaaaata gcaataccta ttgtactttg
    13201 tctgcttatg gcagatttta ttttagggct tatatcaaga agtgtacctc aattaaatgt
    13261 aatgatagtt ggtatgccat taaaaatatt ggttggtatt gcattattta tcatatcaat
    13321 acctttaatt gccaatcaaa taagtcattt attaagtcaa ataccaaaga tgtatgaggg
    13381 aacttttgca ctagctccta tgttttttat gggttcaaca gataaaacag aagaagctac
    13441 tccaaagaaa aagggagaac aaagaaagaa aggtaatata gcaaagagta gagaattacc
    13501 cgttgcaatg actctacttg cattcacctt attagtacct acattatttt catatgtagt
    13561 agatacactt aaatcttcgc ttaattattt tttgagtcta gatttttata tgaacataaa
    13621 ttattcaaac ctagagaaat tagttatagc aggattaatg gattttttta agatattttt
    13681 accaatagct attccctttt tagttttagg cataatagca aacctatttc aggtgggaat
    13741 actgtttact ggtgaaactt taaaaccaaa tttatcaaaa ttaaatccag ttagtggatt
    13801 caaaaacatg ttttctatga gaagtttgtc aaccttaata aaggatatag cgattatatc
    13861 tattttggct tatataggat atacattctt ccaagataat tatttagata tattaaagct
    13921 aggtaacata tacctaccaa ctttaatgta cacagttaaa gatttagtat attcaatatt
    13981 gagtaagatt tgtgtagcta tgatagctat agcagttgca gattatgttt atcaaagata
    14041 cagtcataaa aagcaactga gaatgacaaa acaagaagtt aaagatgaat ataaaaactc
    14101 agaaggagac ccagaagtaa aagctaagat aaaacaaaaa caaagacaaa tttcgtctca
    14161 aaggacaatg caagcagtac caagtgctac tgtaatagta accaatccaa cccacttatc
    14221 tatagcagtg agatatgaaa aagggaaaga ccaagctcca gtagtggtgg caaaaggtgc
    14281 agattattta gcttttaaaa taagggaaat tgcaaaggga aatgacatcc ctataataga
    14341 aaacaaacct attgctaggt tgttatataa gcaagtagaa atagaccaag aaattccaga
    14401 ggacatgtat caagcttttg cagagatatt agtggcagta tataaaatca aaaatagata
    14461 caaagtcccc aaaaggtagg ataagtaatg aataagttta atttaaagga aaatatggat
    14521 gtaatagtgg catttggtgt tgtagggatt gttcttatga tgatagtgcc attacctaca
    14581 tttatattag atattttact ggcaattaac ataagtttat ctgtgctaat tttactaatg
    14641 acattattta caacaaatgt acttgattta tctatatttc caacagtgtt acttgtgaca
    14701 acactattta gattgggatt aaatctttca tcaactagat tgattttaac acagggatat
    14761 gcaggtgaag ttatagaggc atttggaagt tttgttgtag gtggaaatta cgtagtagga
    14821 ataattatat tcttaattat attaattgtt caatttgttg ttataaccaa tggttctgga
    14881 agagtatctg aagtaacagc tagatttacg ttagatgcca tgccaggtaa gcagatgagt
    14941 atagatgcag atttaaatgc aggagttata gatgacaaaa ctgctagaaa aagaagaaaa
    15001 gagcttcaac aagaagcaga tttttatggt tctatggatg gagcaaataa gtttgtaaag
    15061 ggagatgcta tagcaggtct tatagtaacg gcaataaaca taataggtgg aattgtaata
    15121 ggagctgtaa tgctgaatat gactcttatg ggtgcagcac agacatatgt aagacttact
    15181 ataggggatg gtcttgtaag tcagatacct gctctattaa tatctacatc agcaggtata
    15241 atcgtgacaa gagcttctac tgatgaaaac tttggtgact tagtaggtaa acagttaacg
    15301 gcaataccaa aagcagtaat gatgactggt tgtgttctaa tcgtacttgg tatgatgcct
    15361 ggattaccta aaccagcatt tttttcacta ggtataggag ctatagcagc aggttacttt
    15421 ttaggaagag aaaagaaaga tactttagaa gacttggagt ttgaaaaacc tgatatggta
    15481 aacccagata aaaatgaagt agaagatgta acaaatttaa taaatgtaga atcaatagaa
    15541 gtagaaattg gatatggttt aatatcctta gctgatgaat cagcaggagg agatttactt
    15601 cagagaatag catcaataag aagacaatgt gcaatagata tgggtatagt cgtacaaccc
    15661 ataagaataa gagataactt acagttaaat ccaaaccaat acaatataaa aataaaagga
    15721 aatgtagttg gtgggtatga gataatgcct aatatggttt tatgtatgga tcctatgaat
    15781 caaggattta gtatatttgg aataaagaca attgaaccta cttttggaat agaggcactt
    15841 tggatagaaa gtgacaaggt agaagatgca gagttaaagg gttatacagt tgtagattca
    15901 tccacaatac ttataactca cttactagat ataataaaat caaatgcaca cgaattactg
    15961 ggaagacaag aagttaagac tattatagat gcagcaagag aaaattatag tgctgtagta
    16021 gatgaattga taccagattt gatgacactt ggtgaaattc aaaaagtact taaaaatctg
    16081 ttaagagaaa aagtaaatat aaaggataga gttacaatac ttgaaacgct tgcagaccag
    16141 tctagaaata caaaagatat agagcttctt actgaatatg taagaatagc cttggctaga
    16201 agtatttgta ataatttagt tgatgatgat aagacaattg tagtggctac attgtctcca
    16261 gaaactgaag agttgatatc taataattta cagaggtctg taaatggaac ttatccagca
    16321 gttgacccag aaaatacaaa taaaatattt gaaagtatac aagaagtaat gagcaatgta
    16381 tatttcaatc ataatatacc agtaatagta gtatcaccaa agataagagc tccatttaga
    16441 aaattagttg aaattgtata tcctaatttg actgtattat cattaaatga aatacctaac
    16501 gatattaaaa tcaaagcaga aggtgtggtg agcatatatg atgacgaaaa agtatacagc
    16561 taacacaatt caggatgcta tgaatctagc caaaatggaa ttgggtgaca atattacatt
    16621 aatagataaa aaagaagtaa gaaaatctgg aatacaaggt atcttttcaa agaaagatat
    16681 tgaactaact attggatggg aaaagagaga aaacgtagaa caaaaagatt taaaacgaga
    16741 gatagaacaa ttaaagttaa ttattaacaa tatggggttt gataataaga atgataatga
    16801 tatagataaa atatgtaaaa atctactaag tttagaatta aatgaagaaa ttgtagaatc
    16861 tataagaatt gatttgcaag aaatgaagtt caatggaatc gatacaagta aaaatttagt
    16921 agaaatttta aagaaaaaga ttaaaataga aaatcaagta ataaatggta aaattgctct
    16981 agtcggacca ccaggagtag gtaaaacgac tacaatagca aagttagccg caaaattagt
    17041 ttttgaagaa aataaaaaag taggagtaat aactatagat acatacagga ttggtgctgt
    17101 agaacagttg aagatatata ctgatataat gaatattccc tttaaagggg taataagtcc
    17161 tgatgaaatg gaattggcac ttgacgagat gaaagattgt gatgttgtat taatagatac
    17221 aacaggtaga ggctataaaa actctatgca aatactagaa atcaaaaatc ttatagataa
    17281 agctgaaact gataatatac atttagtttt gaattgtaca acaagagaaa gtgatacaaa
    17341 agcaattata gattcatata gaaatgtgaa ttttaaaagc ttaataatta caaagctaga
    17401 tgaaacaata acatatggct caatatttaa cataatgaat tatgcacaaa aaccaatatc
    17461 atatattaca acaggacaaa atgttcctga tgatattata aaacctaatg aagataagat
    17521 tataaggtta ctattaggag ttgaaagtat atgatagacc aagctcaaat tttgagaaaa
    17581 atggcaatgg aaaaaagagg acttgatgag tttatagtag agaatgagaa tgtacctaaa
    17641 ataattacaa tagcttctgg taaaggcggt gttggaaaga gtaatctcgc tacaaatttg
    17701 tctatatgct tgaccaaact taataaaaaa gttcttatat tagatgcaga cataggaatg
    17761 tctaatatag atataataat gggggtaaat gtaaaaggga ctataattga tgtaattaat
    17821 ggcgaaaaaa atatagaaga tataatttca cagactaagt atggtgtaaa tataatatct
    17881 ggaggttctg cccttaatca tatagaggac tttacagaag ctcaaagaaa taagtttata
    17941 catagcatag aacagattca cgatgttgat tttataataa ttgatacagg agctggtatg
    18001 agcaaaagcc tattgtcatt tatatactgt agtactgaat ttttcttaat aacaactcca
    18061 gaaccgacat cattgactga cgcatatagt ttattaaaag ctataagtaa ttttggcata
    18121 aagagaagtg caaatataat aatcaatagg gtaattgatt tagaagaagc aaaatctaca
    18181 tacaaaagaa taaaaatggt tgtggacaaa tttctaaacc ttaatctaga attgtatgga
    18241 tatataatag atgacaaaaa agtaagttta tgtgtaaaaa aacagatacc attcatttta
    18301 gaatatccta caagtattgc atcaaaatgt attatagcca tagcaaagag aatggtaagt
    18361 cagtcaagag aagatattgt tgataataaa agttttctaa gaaagatgtt tagtatattt
    18421 aaaagctaag gaggcgtagt taatgaatag agaagaatta ataaaagaga atatgcctct
    18481 tgtaaagagt atagcaagaa aattttttat accagggaaa ggttttgaat atcaagactt
    18541 agtaaatagt ggagtcattg gattgattga tgcaataaat aaatttgatg ctgaaaaagg
    18601 ggcaaagttt tctagttact cttatataaa aataaaatct gctatattag atgaaattag
    18661 aaatcaaagt ccaatttcta aacataatct aactaaagta aataagtata atagagtggt
    18721 agaaaagttg caatctaaat tattaagaga gccaacttca tatgaaattg caaaagaatt
    18781 aaaggtttca gaaaaagaac ttcatgatat cgaaagtaat atagatatgt taaatattgt
    18841 atcattaaac tatgtaatct ttgaagatac aaatgaaact gtacaagatg taataagtga
    18901 tagagaagag gaagctccag aaaatataat agaagaagaa gaaaagttag agattctatc
    18961 caaagcaatt agtaatttaa atgaaagaga aaaattaata ctttcactgt actattatga
    19021 agatttaaat ctaaaggaga tagggaaagt gctaggtgtt tcagaatcaa gagtttcaca
    19081 actccacaga aaatcaataa gaaacttaag aaacaagata aaagaactta aatattctat
    19141 atagatggtg attgataaga tgatacaaat tatattaata gtagtgtcta ttttaataat
    19201 agtaactata gttataaatt tacataagga atcaaaaaat aaagataaca gatactttga
    19261 taaaatattt gagcaagaat atgaagcaaa tgatagatta ataattgcag aaaaaagaag
    19321 attcttttta gacaaagtac ttgcagaaaa aagaagtaat agtcatataa aagtttatga
    19381 aaattataac ctaataaagg ctaatgaaga aagaaaggaa aacatattta tagaatcaaa
    19441 aaaggaagta agacaagaaa atgagttatc tcttaaagtg aaacatctta taagttcagg
    19501 ttatgatgat gtggaaatat gtaagatgct agatattgga aagggggaac tgttattaat
    19561 aaggagttgt tacaaaatat aaggatatta ttatgtgata aaaaagtatt cttaggaata
    19621 ggtattggta tattaatatc aactttatgt ataatgcttt ttagtaataa tgatatgagt
    19681 aaagcagaga tagaaaaaaa ggccagagcg ttaggcatga aatatacaag tgagatgaaa
    19741 gttttagaat agatgatact gtttagacat ttacaaaaaa ggaggtcata atgtgataag
    19801 aggattatat acagcagttt ctgctatgat aactaatcaa caaaagcaaa atgttgttgt
    19861 caataaccta gctaatatgg atacaaatgg atataaaagt aaacaacttt tgactaaaag
    19921 ttttgatgaa ttaaagttgg agggttacaa taactacgca aatggaacta aacaaaagca
    19981 gattataggc gatataagtc caggtatttc tatggatgaa actatcacaa attttaatca
    20041 aggacctata aaaactactg ataataaaat ggatgtagct attcaaggta agggattttt
    20101 tctagttagt gatgcagctg gaaatcaatt ttacactaga aatgggaact tcagaacaga
    20161 caatcaaggt gaccttataa caagtgaagg gtattatgta cttgggacga atactgctac
    20221 tggtgctgta ggtcatataa atgtaggaaa tcaaaaattt gaagtggcaa aagataatac
    20281 aatatcacta gacggaaatg ctatgtataa atttaatatt gtagatttta ataactacaa
    20341 taacttaaaa aaagaaggag ataacttata ctctggagga ggagctatga aagtaaataa
    20401 tgcacttaca atacaaagtg cgatagagtc ctctaatgta gatatggtat ctgaaattaa
    20461 taatatgatg acaatatcaa gagaatatga agcaaatcaa aagataattc aggctatgga
    20521 ttctaaatta gcaaaaatag caagtgagat tggttcagta agataggtaa taggaggtga
    20581 atttttatgt acacaatgtt ttatactagt aaaacagctt tatcagcaaa tcaaagtaaa
    20641 ctagatataa tatctaacaa tatagcaaat tctgattcaa caggatataa aaaaataaat
    20701 atggaatatt ctgatttagt ggatgaagta ctaaatagac catcatatcc tacaaatggc
    20761 aatgatatat cgactggaac aggagctaag gcaacagctc ccatgagaaa ttatgaacaa
    20821 ggtgcattgg ctcctacaga tagtaagagt aatttggcaa tagatggaga aggattcttt
    20881 agagtgataa gaaaagatgg tacatatgca tatacaagaa atggtggatt taatgtagat
    20941 gctttaggta agattgtaga tgataatgga aatatattag atgtccaatt tgatgcagga
    21001 tataactata ataatacaaa tatagatagt acaaacctga cagtttcaag aaatggagag
    21061 ctattcgtag ataataaaaa aataggaaaa atcaacttat atcaacctat aggaactcaa
    21121 aattttatat ctgaaggaga tagtttattc gtcgcaactg atgcagcaca gattaaacaa
    21181 gttgagaaag tcgatatagt tcaaggctat agagagaggt caaatgtttc tttacaagaa
    21241 gaatttgttg acttaatagc cactcaaaga gcatttcaaa tgaactcaaa gggaataaag
    21301 acagcagatg aaatgtggca aatagcgaat aatttaagag ctaaataatt atgtaaggtg
    21361 aggaatattc atgaatgata tgaaagagta cgattttggc aaacctcaga gttattcaag
    21421 agaaaattta acttgtttaa attttttatt agctgaattt tgtaaaaaat ataaaaacta
    21481 tataatttat gaacttaagt gtaattctag tatggttgtt gatagtatag accaagtaaa
    21541 ttatcagact tttttagata gagtaacttc ttcgtgcgta gtagtacaaa atgcaatgga
    21601 acctgttatg aaaaactttt cttttagaat agatagaagt gtagctgata tgtggattga
    21661 tataacttct ggaggaactg gagttgtaaa ggataatgat agagagctta cagaacttga
    21721 taaaaaagtg cttttacacc ttatggatga tttagtaaga aatatgcact tatttgaggg
    21781 ttttgaaaat atacaagtat tggatacaca tacacatatt aatttgccac aattatgttc
    21841 tccaactgca ccagtatgcg ttgtagattt aaaagtgcta aatgataatg agtgtattgg
    21901 aagtgtttct ctttgttttc catacaatgg tttagaggct ctgttagaaa gtatatctgt
    21961 tatagaattt tttgataatg atgtaggaga tgattcagag gaatttacca aaaaaatcta
    22021 taatagtgta tctaatatag aattatcagt tattgcagag ataggaaaag tatcaattaa
    22081 tgttgaggat ttacttaaac tagaagttgg agatgtaata gtaacaaata aaaaaataaa
    22141 tgattatata gatatatttg tagaaaattc aaaatcatac acagcaacac caggatttat
    22201 atcaagtaaa aaaggtgtaa aaataaatga tgctgttgga aaagaggtgt agttatggac
    22261 aatagtaatc ttatttcaga tgaagaagca aagatgttat taaatgataa agttgaaagt
    22321 gaagttgatg gagatgatga gttagcctta gatgtctctg aagttaatcg aaataatata
    22381 caaaggatac ttgaccttaa gttagaatta tctgtagtta taggaagaac taagatgact
    22441 ctaagagata ttttaaattt acataaaggt tctcttattg aactggatac tttagcagac
    22501 caagatgtgg aaatactaat agataataag gttttggctt atggaaaagt agtggtggta
    22561 gatttaaatt ttggtgtaaa gataacaagt atagtaagtg aagaagacat ggtaaaatct
    22621 cttgtttaga gataacatca attaatactt aaggcatgag gtggtactta ttttaaactt
    22681 aaatgatata aaaaaagata tactaaaact caataaaaaa gactcatgtt ctctatataa
    22741 tgaatctatt aataatataa ataataattg tatatcaact ggattaaaat ttttaaaaca
    22801 agcaagagat ttaaacccag atgatgttga tatattaaat ctcacaggtc ttgtaaactt
    22861 actaaaatgt aattttgatg atgctgtaga aagtttctat aagagttcac tttgtgaaaa
    22921 aactgctctg tgtgaaaagt atataaacat gcttacatct gaggagtttt taattttctt
    22981 tgaaaagtac aatcaactta taaggttaat aaataaagga atgtataaag aagctataca
    23041 agggtttaaa cttataactg accaatactg tgatttaata gaaccttatg agttgcttgc
    23101 cttactgtat gacaaggaag aagaatatat aaaatttgat gaatgtttag aagtattgaa
    23161 gattattgat aaggaaaatt atttattaaa tcaagaaaat aacacattag atatgtataa
    23221 tagtgctaat atacaaacta aaagtaatat aaaagtagat gattataaga atgagttttt
    23281 acataaaagt agtagtaatc ataaaattaa tgattataat aatgtaacta aagaaaagag
    23341 ttcaagcaaa aaccagaaaa gttcagattc taataagaaa aaaagtatta aaaaaaataa
    23401 atacctatat atagccataa tattaggaat attattagta ggacaaagta tatatagttc
    23461 ttataagatg aataatttaa ctgataaaat atctaaaaat aatgaaacca aaaatgaaga
    23521 gtcaatagat tctaacttga ctaagaaaga aaataatata gaagaaaatg aagatatgag
    23581 taaggcttct aatataaata agagtaataa aaacattaat aaagaggatg atgtaaaatc
    23641 taaaaaaaat actgtaaaaa atgaagatga taaagattct gacttattta cagaggatga
    23701 attgatgtct aaggcgaata ctttaaaatc agaaaagaaa actaaatctt ctatacaact
    23761 atataagaaa gttgcagata taggtgaaaa taaagggaat acatctgaag caacttatca
    23821 agttgctatt ctcagtgaaa agttaaaaga ctataaaact gctgaagaat attataaaat
    23881 gtatgtagaa aattactcag aaaaagatgc ttattttgat gaatcttatt ataatttagg
    23941 tatgatgtac tataacaatg gtgatttaaa aaattctaaa ttgacattaa agaagttggt
    24001 taataaggta ccaaatagta tgtataataa ttcaaaagta aaagaaattt taaaagaaga
    24061 atagttaaat tagataagaa aaataaatta ttttatttta aaataatatg attataatat
    24121 attgacatac cattttaaaa attttaaaat attaattata aaatgaggag ggataaaaaa
    24181 tggaatttga aaaagggagt atttcaattc atacagaaaa tatttttcct ataattaaaa
    24241 aatggttata ctctgataaa gacatattta taagagagct tataagtaat ggatgtgatg
    24301 cagtaagtaa acataaaaga cttgtatcac taggagaaat atcagaaaat aagtcatcag
    24361 attataaaat tacagtatct gtaaataaag gggaaggtac acttaaattt attgacaatg
    24421 gaattggtat gactgaagaa gagataaaaa aatacataaa tcaagttgct ttttcaggtg
    24481 ctgaagattt ctttaataaa tataaggata agatggaaga gtcaaatgat ataataggtc
    24541 attttggatt aggattttat tctgcattta tggtgtctaa aaaggtacaa atagataccc
    24601 tttcatatac agaaggtgca actcctgtaa gatggatatc tgaaggtggt acagaatacg
    24661 aaatatctga atcagatact agaaatgata gaggaactac tataacacta tttattgatg
    24721 atgatagtaa agaattttta gatgaattta ctgtaagagg aataataaat aaatactgtt
    24781 ctttcttacc agtagagata tatttagaag atgttgaaag attagaaaga gaagctaagg
    24841 aagtagaaga aaaagctaaa aaacaaaagg aagatggaaa agaagaggtt gtagatgcaa
    24901 aaataattga gcctttaaac gacactaatc ctctatggtt aaaatctcca aaagactgta
    24961 ctgatgagga gtataaagag ttttatagaa aggtattcaa tgtatttgat gaacctttat
    25021 tctggataca tttaaatgta gattatcctt tcaacttaaa gggtatactt tacttcccta
    25081 aattaaaaaa tgagtttgaa ctgactgaag gaaaagtaaa attatacaac aatcaagtgt
    25141 ttgtggctga caatataaaa gaagttatac cagaattttt acttttatta aaaggtgtta
    25201 tagactgccc agacttacca ttaaatgtat caagaagttt cttacaaaat gacagagatg
    25261 taagcaaaat ttctaagcat ataattaaaa aagtagctga taagttaaaa tctctttgta
    25321 aaaatgaaag agaagaatac aataagtttt gggatgatat acaaatattt attaaatatg
    25381 gttgcttaaa agatgaaagt ttctatgaga aggtaaaaga atgtatatta ttcaaaacta
    25441 ttgatgatga gtatataaca ttacaagatt atttagaaaa atgtaaggac aaacatgaaa
    25501 ataaggtatt ttatgtaagt gataaggaac agcaatctca atacattaaa ctatttaaag
    25561 aatacgactt aagtgctgtt gttttaaact catcaataga tactcatttt atttcattta
    25621 tggaatataa agagaatgga gttaagttta atagaataga tgcagacctt tctgatgtat
    25681 taaaagataa aaatgaaaat aaagatagtg aagaaaacaa agaagagata gctaagatag
    25741 aaggtttgtt taaagaagct gttggagaaa gagtgaagaa ttattctgta gaaggattga
    25801 aaaatgaaga cactccagct atggtattag tatcagaaca atctattaga atggcagaaa
    25861 tgcagtcaag atttgctgga atggatttag gaatgaattt tgaggaagaa aaaactcttg
    25921 taataaatga gaacagtcca ataatcaaaa aattggtttc tcttaaagat gatgaggaaa
    25981 agaaagataa gattacgctt atttgtaacc agatagcaga tttagcttta ctttctaata
    26041 aagaattaaa gccagatgag ttagattcat ttgtacaaag aagtaataag cttatgagtc
    26101 ttttgataga attataagat tgaatttgaa tacattgaag caaatttata aaaagtattc
    26161 aatatcagtg atgagaaaga agtgtctcaa aatgaacttt tcagttcatg aggcgctttt
    26221 tttatgtgaa attaaattta ttttaatcat ttcaacaatg aaaaatatat ttatctctat
    26281 tttgagacag accgttcttt atttttttat ctttggttaa tttttaaata tttaagtagg
    26341 ttctaataaa aaactctatt tagttaaata tagttaactt gatatataat aagataatac
    26401 atataattaa gtaaaagatt gttttttagt ttatgtttaa atacataatt acactttgtt
    26461 aaaaacataa aattattact aaagtagaaa taggaggttt tagcatgaat tttaattata
    26521 atttgccagt aaatatctta tttgggagag gcagaattaa tgatgtggga aaagaagtat
    26581 ctaaatatgg caaaaaagta ttgatagtaa caggtaaaaa tagtacaaag aaaactggat
    26641 tacttgataa aacaatagat ttactaaaag actctaaaat agaatataaa gtttttgata
    26701 gagtagaaca aaatcctctt ataactacta tatattcagg agtagaaatt ataaaatcaa
    26761 ctggatgtga ttgtgtttta ggtcttggtg gtggaagcat tatggatgct gccaagagta
    26821 tagctttttc ttataaaaac ccaggagatt taaatgatta tatatttgga attagacaag
    26881 gtgaagaagc tttacctata atcttagttc caacaacatc aggtacaggt agtgaaggaa
    26941 attgttttgc agtacttaca aattcagaaa ctaaagacaa aaaatctata aagaagaata
    27001 gtatgtatgc aaaagcatca ataattgacc cagaacttat ggttacaatg ccaaaacata
    27061 taattgcatc agttggattt gatgcacttg cccataatat ggaagcatat ctttctaatg
    27121 gaagaaaccc tcttgcagat gtacaagcta tttatgggat tgaacttata tcagaaaacc
    27181 taataaaggt atataatgat gttaatgatt tagaagcatg ggaaaaaata acacttgcaa
    27241 gtactattgg aggaatgacg attggtacag cgggtacagc cttgccacat ggaatggagc
    27301 atcctgtaag tggtcttaga gatgtaatgc atggaaaagg acttgcagct ttgactccta
    27361 ctattataga aagttcatgg gatagtgata ttgaaagatt tggtaatatt tcaaaggtat
    27421 taggaggaac ttgtgcagaa gattgttcag atgcaattag aaatttcctt aaaaaaatag
    27481 atttagatat aaagctaagt gatttaggta ttgaaaaatc agatatagat tggttaactg
    27541 ataattgtat gaaaatatca gttgcaaata ttaagagaca tccaaagtat tttaataagg
    27601 aacaaataaa ggaaatgtac cataagtctt tataatttga ctttacatat ttagttttat
    27661 ataaaaatta taaattaata ataaaaaatt ataagtaatt aatagtaaaa aaattgtgta
    27721 tagaagttat atatataata aatttgtctt aagcttttat tttactttct aataaataaa
    27781 ggagtttaaa aaagggaaga ttaattaagt aatattttat aaaattcttc gatttaaaaa
    27841 ctttaagtag aggtgaaata aatgtttaat cctaaaagaa taatattcga aaaaggaact
    27901 ttagacactg atgtgggtaa aaaaatatac aataaattta gagataataa agatgtagag
    27961 ataattaata tatcatcaaa taggattaaa gaacatattc caggtgaaaa tctatatgaa
    28021 caatatagaa gtgggaagca gactatggta gttgggatta gaaaaagtct gaagtttcaa
    28081 acatgtaaac cttctgctaa ttatcaacta ccacttgtca gtggatgtat gggaagatgt
    28141 gagtattgtt atttgaacac acaattaggt gataaaccat ttataagggt gtttgtaaat
    28201 gtagatgaaa tacttgaaca gacaaaaaaa tatattgaag atagaaagcc acaggtaacc
    28261 atatttgaag gggcagctac atcagaccca gttccagtag agccatatac taattctttg
    28321 aagaaaacaa tagagttttt tggaagagag gaaaaaggaa gatttagatt tgttactaaa
    28381 tacagtgatg tggatagctt attggatgct gaacataata atcatacaga aatacgattt
    28441 agtatcaata ctcctagaat tataaatgaa catgagcatt atacagcttc tgcaaataaa
    28501 agaatagagt cagctgtaaa acttgctagg gctggttatc agattggttt cataatagca
    28561 cctgtgtttt tatatgaagg ttggaaagaa gagtataaaa atctgattat aagtataaaa
    28621 gaagctttac caaaggattt tgataaaaaa attatatttg aagttatatc tcatagatat
    28681 acaactaaag caaaaaatag aatactagag atttatccag atacactatt gccaatggaa
    28741 aatgaagata gaaagtttaa atacggtcaa tttggatatg gtaagtacgt gtatgataaa
    28801 gaacaattag atgatatgaa agagttcttt cttaaggaaa taaatggagt atttaaaaat
    28861 agtttaataa aatatataat atagcaaatc ttacctaaag atttgctata ttttattttt
    28921 atatatttta tgtttataat aaagcaatga gatttagcac tatcatataa gaaaattaaa
    28981 aagggcacta tctatcaaga acattttttc tagttttgat actataaagg ataagagtaa
    29041 caaaaatatc aggaggagtt atagtatgca tgcatgggag tctattcaaa ttacattgga
    29101 tttaatagaa gcaaatttat cagaagaaat atcaattaat gaattagcaa ataaagcaaa
    29161 tttatcacca ttttactatc aaagactatt taaaagattg gtaaataaga ctgtaatgga
    29221 gtatataaag cttcgtcgtc ttgcaagagc ttctgaatac ttagcagaac ataagaatcg
    29281 tatacttgat gtagctttaa attttggatt tgctagtcat gagacattta cacgttcctt
    29341 taaaaaagca tatggattaa ctccagaaaa atatagagca aatccagtaa aactcaatca
    29401 ctttattaag ccagaattaa ttttaaatta tgctatggtt gatgaaggtg ttccactgat
    29461 tgcagatgat atagtgattg aagtcaatcg taagacattg agtaatccaa ggacatttgt
    29521 tggaatagaa atagaagtac ctatttgcca gttggtgggc ggtgaaacaa ctggaattgc
    29581 aatagtagag gaattatgga tgaaacttgg gagtcaaaga cataatatac caaatcaaat
    29641 tccaggtgga aatgaatttg ctgctcttta tatgggaaat gcaaaagaag gaaattgtat
    29701 gtatatggca ggtgtagagg tagagtcagg tacatcagta gaaggatata gtacttttga
    29761 gttgccagct aaagaatatt tagtatgtgg atttgaggca gaaaacttta atgagttagt
    29821 taattcagct gtttttaaag cagataaatt tatggaaaga tggatgaaga aacataattt
    29881 aacaactact gattttgcaa ttgagatgta ttaccccact acacctgaag cagcatatct
    29941 ggaacattgg attgttccgg ttcctattga acaatagaaa ggatgatgaa tatgaattgg
    30001 caagatgcgt tttttcaaga tactaaacct acatttgagc aaattaatga atttattaat
    30061 aatccattat gggacaagtt aaataaaact ttggtttcta cttataatgt agaacctaag
    30121 cttgaataca gtaaatgttc aatgcaaaga ggttggaatg taaaatataa aaaaagaggt
    30181 aaatcactat gtactttata tccacaagaa ggttatttta aagctttggt tattgtaagt
    30241 gaaagcaata gagtagaggt tgatttattt attaatactt gttgtgatta tatcaaaaaa
    30301 atatataatg aggtaaactt ttttaatgga agtaaatggc taatgattca agtagatagt
    30361 ttattggtat taaacgatat gcttgaacta attaaattta gagcttaaca tatagaacag
    30421 gatgaatata taagtcatcc tgtttttata ttcaatcaga taaattaata tatagtctat
    30481 aatatgaata atttagtaaa tttaaattta ctttatcttt ctacattctt tgcaactaag
    30541 tccacatgtg tttttttctt gcatattagt agcaccccaa ttagcaaatt gttgtaaaat
    30601 aggcacaata cttttacctt tacttgttaa tgtatattca acttttggag gaatttcatt
    30661 atattgttta cgatgaacaa taccagtaga ctctaaatct tttaatgatt gagctagcat
    30721 agtatttgta atgccatcca attttctttt tatgctacta tatctaattg gattttcaac
    30781 tgctaacata catataatag gtaatttcca cttaccaccg acaatgtcta atgcataacg
    30841 gattggacag gttaattctt caacgttttt agttatattt ttttcagtat ttatactcat
    30901 tttaattact ccttagttat agtagtatct tttttatact ttatcagaaa aaactgcata
    30961 cttgtttttt ctgtatttta tattaaaatt atatcaaagg ataatcctta atacaagtat
    31021 ttaaaagggg tgtaagaatt atgaaagcat tagaattttt gaacaaggca ggagtttatt
    31081 atttagcaac agttgatgag aacaatcaag cacatgtgcg tcctttagga tttgttatgg
    31141 aatacaatgg taaacttaca ttttgcacat ctaatcaaaa ggatatgttt aagcaactta
    31201 tttttaatcc aaaggttgaa ctttgttgta tagaccaaaa ccttaatact ctacgtattt
    31261 taggtgaagc agtatttgtt acatcaaaag aaacacaagc taaggcactt gaaataatgc
    31321 caagtttagg tcagatgtac tctgtaggag atggtaagtt tgaaatattc tctattgata
    31381 aggcaaaagt tagttgttgt tcaatgagtg gtaaaaagat tgatgtagag ctttaattat
    31441 aattgaatcg acatccatag tgaaaattaa gaaaacgtta ttactgaaat attgatagat
    31501 ttaatttaaa tgcaataaaa agatttttaa ataatgaata tgtaaaaatt tttagttatt
    31561 agatgtgtat ttcaataatg atatactatt ttgaataatt acatactaga aataagataa
    31621 ttaaaattta ctttataatg ggatagattt cttttaaaaa tattttaact ataattgatt
    31681 tttatttaat ctgaaaaaaa tattatgact ataaaaaatt gctacttatt atttggatat
    31741 ttttatatat aaataataag tagcatgact ttatacatta ataatgatag aatataaatt
    31801 aatagataag atatgatttt aaaaggagtg atataagatg agtaaatata gttctttatg
    31861 ggaatatgtt aagaaaaaca atagtcaatc gtttaaatta acttttgaag aaataaaaga
    31921 tattgctggg atagagatag accattcgtt tttgaaatat aaaaaggaat taaatgaata
    31981 tggatatcaa gtaggaaaaa tctctttaaa agagaagact gttattttcg ataaaattgg
    32041 ttaagacata aataattaca tataataaaa taatttgtat tgatgattat tacaaataaa
    32101 aaagggcgta gcactatttt ttagtgtcac agcccctttt ttgtttataa ttatgtacat
    32161 ttcacattat cacgatataa gcatttttct tatgagaaaa ttaattagaa ttatttttat
    32221 tcatatttaa attatttaaa ttgttttccc agttttttat ctccttttta acttcttcac
    32281 ttaaagtatc acttgaagat attttcttta atttatcatt caaagatttc ttttgttcct
    32341 ctgaaagatc tgtttttatt gtaggatcaa taatatctat tacatctttt acatcaaaat
    32401 caacaaattt gcacagttct tctagatgat caattagaaa atctagacct tcatatgacc
    32461 attctttata atcttttccg ttttttaaca gaaactcatt cacttggtaa ttctgatttg
    32521 ctaattcaaa gaatgaacct gaaggatcca ttatatcatt tatagagttt tcatagttaa
    32581 caatattaat ttgtcttatt aatttctctt tttctgttaa gttgctataa ttcttgttaa
    32641 caaaagctac taatccaaat tcaaagttta aaattgaatc tttacgtttt tttactgaat
    32701 cttctccaaa ttccctaaga ccttctaaat ttttatcaat ggctttatct ctaatctcta
    32761 ttaattgttc tatacttaaa ccttctaagt ttttaggtac tatttcttca ttattcttag
    32821 taacttcttt caatttattg ttagtatttt tattattgaa aataaatata gcagttaata
    32881 aacttaaaat tattactaaa ataattaaac ttacattttt tttacttaac atattaaacc
    32941 tcctttttta aataagtatt gtacttgtga aaaataaatt tgtttatgaa gataacattt
    33001 actactgttt gttctaaaga ttataataga atattttttt gatataatct atatttttct
    33061 tattaaattt tcttattaga tatt
//
LOCUS       DAEORM030000043        30747 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.043, whole genome shotgun sequence.
ACCESSION   DAEORM030000043 DAEORM030000000
VERSION     DAEORM030000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 30747)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30747)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 30747)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30747
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.043"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            213..2114
                     /locus_tag="KRH23_002609"
     CDS             213..2114
                     /locus_tag="KRH23_002609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HHS5225887.1"
                     /translation="MRERIILETLKNSSGYLNIDYFADKLGVSTRTIRNEIKKIETIK
                     ECNGFKLEYKSKLGYILNIKDQDKFEHYLRNLPSDLVENPEQRLESIIVELLVNEGYK
                     TIEQLSKKFLVSSSQIKNDLKKIDEKIKDTELKLERKAHYGIKIEGSIKEIQSILVDS
                     YFRGNRNITEYRNKFIDNLKLANIRSTIKNVLNEHDLEANLTELEEILAQIIILYIRV
                     SMRVAGNASDLKLYTEDLIIDKLLDKIFRDKKYNLNYDEKYYLKELIKLKTKDKKATI
                     KNIDKNKLQDIMFEFFREIDKKYNSNFLEDKEFFNLFYLHIACLIERIKKNHKIINPF
                     SVKISQQYPTVFNLSIQFSKIIENEYHIKISQDEIGFIATHIAVPFEKREEANFNKKY
                     KIAIICSSGGGSAFLINLRLKEIFPNAEIRNFSLLEEKAVIEFAPDLIFSITNLLFEI
                     NAPVILINEILDELDYLDIKESVRFADHIGNISSPKQYILGLFDKNHFRCIKDKAKYK
                     DILDSMSKCIVDEGACSPTYPKDVWERESYLSTIYTNGVAIPHPIEMTGNKNIISVAL
                     IQTDIIYENRVPKIIFMISLIKGNLELHKQISKYLSKIMANKDMVDMLNKSQSYEEFM
                     YKLKIYLGG"
     gene            2117..3160
                     /gene="ypdE"
                     /locus_tag="KRH23_002610"
     CDS             2117..3160
                     /gene="ypdE"
                     /locus_tag="KRH23_002610"
                     /EC_number="3.4.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HHS5225888.1"
                     /translation="MNIEFFKRLSEADGIASNEEEVRHVLLEELKAYSDKIICDGLGS
                     IIFSKIKDESAPNVMICAHMDEVGFMVRSIDKLGMIHLITIGGVKPLAQFVQKVRITT
                     KEGKKIPAVINATYNNGKAENIYADIGAYTEEDVYNLGINVGDMVTYTTSFEEFTLPD
                     RLVGKAFDDRIGCFVMGEVLKELRKENLNCNIHFAATSSEEVGIRGAKTSTQLINPDI
                     VFVIDVACAKNEFVRDYTNQKQIDKGVMLMHRDRTLVPSRKMIDYVMEIADKNNIPLQ
                     HDMFESGGTDGGEAHLVNEGKPCVVTCVPVRYGHCAFSIVSNKDLENIIRLYTQLILN
                     FDEEQYKHIRNFI"
     gene            3175..3480
                     /locus_tag="KRH23_002611"
     CDS             3175..3480
                     /locus_tag="KRH23_002611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HHS5225889.1"
                     /translation="MSTEVQIMELISTAGESKSKAFEALKKVKSKDFKGAKLLIEEAR
                     KIDIEAHRIQTELITQDLNEDVESPAMSLLMVHAQDHYMTSQLAKDLIEALIYCLDK"
     gene            3577..3912
                     /locus_tag="KRH23_002612"
     CDS             3577..3912
                     /locus_tag="KRH23_002612"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HHS5225890.1"
                     /translation="MKILLCCAGGFSTNMLMQNMKKVVKESAKLNEKDFEFTAIPADS
                     IESEVDDWDIVLIGPQIAHKIDFLKGILEPKNKPFAVIDKDVYGKMDGATVMKLALIT
                     YKKHQLAQG"
     gene            3944..5266
                     /locus_tag="KRH23_002613"
     CDS             3944..5266
                     /locus_tag="KRH23_002613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HHS5225891.1"
                     /translation="MFSKFEAFMNRVFMPLAHKVDNQRHLGSIKAGMVAMTPFTILGS
                     IFAILPALPNMLGENNPISKFILNNSAILDLPVSLSIGLIGLYACMCIAFNLGNYYKL
                     YIPGCVALSTFSFLFLVASFTPDGALEIGNLGAKGLFTGMIAGLGSVELYNFCNKKNI
                     TIKMPENVPDFVSRSFELIPTTIIVCGTFIVARFISLKVFGELPPQILTQFLSPLVGS
                     MDNPWSVLALNFAICTIFFFGIHSSVFSPITRPIMITFIAENIAAMQAGETIPHFFTA
                     GASSAFFGFTGCGISIGCVIACMLSKNASYKKIGRVSLFPALFGINEPILFGAPIILN
                     PIMFIPHVFGGAIIGTLPMFFMHWGWLAKPVFDPPYVGVFLEGFLTNGDWHSILANAL
                     QLVLAVLLYWPFFKIMERQQNNKKQKEETKNIFSKEEEDLLDDLGLDF"
     gene            5276..6346
                     /locus_tag="KRH23_002614"
     CDS             5276..6346
                     /locus_tag="KRH23_002614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M24 family metallopeptidase"
                     /protein_id="HHS5225892.1"
                     /translation="MNNTMERLVSLIYKRGVDALLIKAKNTKRYIGALSGSGVYVLVT
                     KDKNYQILDGRYIDEADKKTTGFIKRIVSQGSYIPTIIELLKELNIKKLAIENQAMSI
                     QEYLSLKNEGFEINLITNELWKLRAIKSKEEIEFIKKACEITDEVFDEVISEIKKDMT
                     ELEVSALIQYHALKKGASGMSFETIVVSGERGAMPHGRPTNKKLKVNEAITIDFGVVY
                     QGYQSDMTRTISIGKPPKIIKEIYDVVLEAQLSAIESIKEGTRASDVDKVARKIIDKH
                     GFGKYFNHGLGHGIGLGDGEVPTLNPNSEDILVEGMVMSCEPGIYIPNVGGVRIEDDI
                     VIIDGKGVPLNKTSKEFIILGE"
     gene            6351..7538
                     /locus_tag="KRH23_002615"
     CDS             6351..7538
                     /locus_tag="KRH23_002615"
                     /EC_number="4.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0047804 - cysteine-S-conjugate beta-lyase
                     activity [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MalY/PatB family protein"
                     /protein_id="HHS5225893.1"
                     /translation="MKYNFNKVLNRKEGNCRKWSNHVIKEKFGLNEDAIPMDLADIDF
                     ECAPAIKESILKRASVGDYSYTFIGDDFYDAIINWNKRRFDVYIEKDWIKLTFGTVST
                     LHYIVQAYTKEGEGVLINTPAYDPFAEAVVNNNRKLCCSSLKLDNNRYYLDLEDMENQ
                     MKYENIRLLIFCSPQNPSGRIWTKEELYQVSELCLKYNVILVSDEIHRDIIFKDYRFV
                     SLWNAHPEIYKNSIICVSPNKGFNLGGLKTSYVLIRDVKIRETLLERLKSNSITSPNV
                     FAIPAIVAAYNESEEWLDAMTSYVEENFEIVYDFFETNIPKAKVMKSDSSFLAWIDVR
                     EVFRNEEESKEFFRHANLTMVVGSYFVKDGDGFIRINVGCPRETLNEALNRIKKTYIS
                     MYC"
     gene            complement(7735..8607)
                     /locus_tag="KRH23_002616"
     CDS             complement(7735..8607)
                     /locus_tag="KRH23_002616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HHS5225894.1"
                     /translation="MNILQNENLIIESSSFGAELTKIFSKKYDKNILWDGNKKYWGRQ
                     SPILFPIVGKLFDNETIIEENLYSMTQHGFARDMDFEIVDKGDTFVTYKLTDNESTLK
                     KYPYSFELIINYTLNDNSIEVEWIVKNTDSKDIFFSIGGHPAFNLPFYKQNDFSKHYL
                     EFKSKNDVEKINLNGSFTDDIIPIGKLKNLQLNPEVFKNDALIYTNIDEVSICNNDGS
                     KYVTISMEDFPLVGIWTPYYSETNSTAPFLCIEPWYGLADSINSNKIYKDKKFINKLS
                     KGKVFTASYNINIH"
     gene            complement(9001..9192)
                     /locus_tag="KRH23_002617"
     CDS             complement(9001..9192)
                     /locus_tag="KRH23_002617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5225895.1"
                     /translation="MDDFSKLKSLYEDGYRCIYHDCVDNNYTIYLKNFYTEGSETIEL
                     SSESDFSQFKDYIDGLRMS"
     gene            9411..10457
                     /gene="cobT"
                     /locus_tag="KRH23_002618"
     CDS             9411..10457
                     /gene="cobT"
                     /locus_tag="KRH23_002618"
                     /EC_number="2.4.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008939 -
                     nicotinate-nucleotide-dimethylbenzimidazole
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide--dimethylbenzimidazole
                     phosphoribosyltransferase"
                     /protein_id="HHS5225896.1"
                     /translation="MSLLESISKNIYSLDNSSIEKTKQRLDRLIHPTGSLGKIEDICM
                     QLAGIFGNENFDTSKKVIIAFAGDHGVYEEGVAPDPQNITKLQFPNFSKGLCGVGVIS
                     KFVGADVVAVDVGINCDEKLDGVLDYKIRKGTSNMAKGPAMSKQEAIRCLEIGIEIAE
                     QCIEKDYKVIGIGEMGIANTTPSTAIISVISGCDPLEVTGIGAGLKKERLKHKAEVIR
                     KAIEINNPNPTDGVDILSKVGGFEIGSMAGVILGCSANRIPVVIDGFISYAAALIAYK
                     INPKTREYMIASHLSAESGTKRALDILKLDPLLNMDMRLGEGSGAALAFDIIEASNYT
                     YKNMATFDEIDMGR"
     gene            10489..11049
                     /gene="cobU"
                     /locus_tag="KRH23_002619"
     CDS             10489..11049
                     /gene="cobU"
                     /locus_tag="KRH23_002619"
                     /EC_number="2.7.1.156"
                     /EC_number="2.7.7.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0043752 - adenosylcobinamide kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional adenosylcobinamide
                     kinase/adenosylcobinamide-phosphate guanylyltransferase"
                     /protein_id="HHS5225897.1"
                     /translation="MSKIILVTGGARSGKSNFAEKLCFDRNNNTAYIATSIPFDDEMK
                     DRVKKHQENRPRNWNTYEIYEDIYSIIKEIYKEHETVILDCVTLLVNNLMFEHNLNIE
                     ESSQEEINKLEQYIKEQVVKLIEEIEKTNLYFVFVTNELGMGIVPGNKLSRIYADIVG
                     RINQYIASKSNEVYFVVSGIAMKIKE"
     gene            11059..11832
                     /gene="cobS"
                     /locus_tag="KRH23_002620"
     CDS             11059..11832
                     /gene="cobS"
                     /locus_tag="KRH23_002620"
                     /EC_number="2.7.8.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008818 - cobalamin 5'-phosphate synthase
                     activity [Evidence IEA];
                     GO_function: GO:0051073 - adenosylcobinamide-GDP
                     ribazoletransferase activity [Evidence IEA];
                     GO_process: GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobinamide-GDP ribazoletransferase"
                     /protein_id="HHS5225898.1"
                     /translation="MKRFILILQFLTRIPIKLNVGFDDEFYKSIVYFPLVGFVIGILS
                     YLIGWISMLLFEPFIASIIITLAGVLITGGLHIDGLGDTFDAIYSYRDKEKMLEIMKD
                     SRLGTNSLLAIMFVLLLKAGFVYDIISNNSLWVIIFMPMIARLGVMLLTYKTVTPREK
                     GMGNLFIGKLTTSMLITAIIYTLLIVALITKFIFLLPNIVLIKVLGSAIVVFVFIILF
                     KKHIYKKIDGVTGDILGCGIELSELVYLIYIYLLIFVFF"
     gene            11852..12466
                     /locus_tag="KRH23_002621"
     CDS             11852..12466
                     /locus_tag="KRH23_002621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HHS5225899.1"
                     /translation="MIRLILIRHALTNDNKKGKLSGHRNSCISEEGKLQINKITRYLS
                     NENIDKIYTTPSTRTKDTIEKISKLKLLEIEEKETLREISFGDFEGITFEEIKIKYPN
                     EFEKMIKEGNNYRYPNGESLIDSYKRVAKEIDNIILENDIDLDTKTILICSHAGTIRN
                     IITHLISGSYKYHWNFKIDNASITVLEIDGGFAVIDKMNFTDFI"
     regulatory      12533..12711
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
     gene            12827..14341
                     /locus_tag="KRH23_002622"
     CDS             12827..14341
                     /locus_tag="KRH23_002622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cobyric acid synthase"
                     /protein_id="HHS5225900.1"
                     /translation="MGKKIMLQGTASNVGKSVLVAGLCRIFKQDGYTVAPFKSQNMAL
                     NSFITKEGLEMGRAQVFQAEAAKIEPIADMNPVLLKPSGNNKSQVIVRGKVVGEMPSS
                     KYHDYKLELVGVLKETFNSLNSRYDIVVMEGAGSNAEINLKDRDISNMGMAEIADAPV
                     IIVGDIDRGGVFASLAGTMLLLNEDEKRRVKGVIINKFRGKKELLQDGVKMLEDIIKV
                     PVIGVVPYTDIKIEDEDSVTTRFKKKMNKSDIHIEIIRTPHMSNFTDFNIFETQEDVS
                     IRYVDYGESLGNPDILIIPGTKSTIDDLTYIRKSGLESQIKNLHSQGKLIFGICGGYQ
                     MLGKKLKDPYHVESEIEEVDGIGLLDTETTFEKEKTTTQVEATIVECISEYMNNLKGK
                     KVKGYEIHMGITKRGNDVRSLDLITKKLDKEVNYTEGSVNKEGNVIGTYLHGIFDEIS
                     FTRAILNNIRKKKGLGELESKVNSFNEFKDKEYDKLADFLREHLDIEKIYEIMK"
     gene            14380..15756
                     /locus_tag="KRH23_002623"
     CDS             14380..15756
                     /locus_tag="KRH23_002623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042242 - cobyrinic acid a,c-diamide
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cobyrinate a,c-diamide synthase"
                     /protein_id="HHS5225901.1"
                     /translation="MKKILIAGTNSGVGKTTISLGIMQALVKRNMKVQPYKVGPDYID
                     PSYHTFITGRHSRNLDSYMLDDEKIKYIVNKSSKDADISVIEGVMGLYDGFGIDLDNC
                     TSSHTSKVLKSPVILVINGKSMAASSAAMVLGYKELDKDVNIKGVIVNNVKTNSHYQI
                     IKSSIEKYCNVEVLGYFPPNNKFSLESRHLGLVPSVEMKSLREKFYTLADEIEHYIDI
                     DRIIEISESDEFESDFDFQTLIENNKIKEHVNNKSIAIAYDKAFNFYYRENIELLEEL
                     GLEINYFSPLEDASVPNADYIYIGGGFPEIFGKELEANESMRTSILEAHNNNIPIYAE
                     CGGLMYLGEKLLNQEEQEFNMVGIFSGISKMTSSLKRFGYCIGVAKENTLLSKKGESI
                     KGHEFHHSIFESDEKCVYSMRKERDGNIVEEWYGGYSKGNTLATYLHTHFYNNLNCIE
                     NFLKKGNK"
     gene            15757..16728
                     /gene="cbiB"
                     /locus_tag="KRH23_002624"
     CDS             15757..16728
                     /gene="cbiB"
                     /locus_tag="KRH23_002624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0048472 - threonine-phosphate
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobinamide-phosphate synthase CbiB"
                     /protein_id="HHS5225902.1"
                     /translation="MSILSIYIGYVTDLIVGDPYSFPHPVRFIGKLINFTQGIIRKVS
                     KNDRQLKFGGFILWFITVGITYLTTYAIVKLFSFNILLSIVVNSFIIYTTLATKCLKD
                     EALKIYNVLKTEDIEKSRIQLSYIVGRDTTNLSEPEIIRATVETVAENTVDGIIAPMF
                     YAFIGGAPLAMAYKAINTLDSTVGYKNKKYKDIGFASAKIDDIANYIPARISVILMTI
                     GSFFLNYNYRNCFKISIRDRKNHKSPNCAFSEGAVSGALGIQLGGTNVYFGEKVYKPT
                     IGDKLREIDKEDIIKTNKIMYASSFVSMLVFTLIYVLCRMILINLII"
     gene            16760..17830
                     /locus_tag="KRH23_002625"
     CDS             16760..17830
                     /locus_tag="KRH23_002625"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008483 - transaminase activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HHS5225903.1"
                     /translation="MKDLGHGANVDEMARLYGKNPKEIIDFSSNINPNVLPNLERYIL
                     KGLEECRNYPDINYTNLRENISKYIDINPDFIIPGNGATEVIYLLMKSIKKKLAIINP
                     TFSEYRRSAELNNLDIIDLELDLENNFKLNIDIIKENIKRFDSLFICNPNNPSGNVQD
                     LKELVHLLDKHNKVLIIDETFMEFVEDESKYSLVKYIESNKNIFIIKAVTKFFGMPGL
                     RLGYGLTSNTEIMNKIYEHKEPWTINSFADILSNFIFEDKEYIKNSKEYYIEERKYML
                     QELRNIRNIKVYDTDANFILIRIYKKTTKELKKDLFKQGNILVRDASNFIGLDDSFIR
                     VAIKSHEDNKILIENMKNLLGD"
     gene            17832..18719
                     /locus_tag="KRH23_002626"
     CDS             17832..18719
                     /locus_tag="KRH23_002626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin biosynthesis protein"
                     /protein_id="HHS5225904.1"
                     /translation="MKSYGICPASCGEFVQGIIDDEEYLCSYAIDMYSKVYIEEKLVD
                     INLGRYKSRLAIEKVFEKFNLPKKYTKNISLNINSKIPVGKGMASSTADIGATIKATL
                     SLIDKDLSSEEISKLAAEIEPTDSIFIDKNSIFNPLNGTVIKYLGNLTNAKVVILEPN
                     KVLDTMKIRLRQDYNKLKVENKEVIKKSFALLEEGLKKNNLSLVGEACTLSSLANENI
                     EKKEYLNEIIKISKKYGAYGVNIAHSGTVVGILIDKSMNDKKMIDALCESNINSVYNK
                     IYTQNIINGGIKGEIEWNT"
     gene            18707..19339
                     /locus_tag="KRH23_002627"
     CDS             18707..19339
                     /locus_tag="KRH23_002627"
                     /EC_number="5.4.99.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-8 methylmutase"
                     /protein_id="HHS5225905.1"
                     /translation="MEYIKNPMKIEEKSFELIQEIIDEIRPDYKFKNNIEEKIIKRAI
                     HTTADFDYLDILKISEEAVDSIIDALKNNASIYTDTNMALSGINKRKLESLGCKYKCL
                     VADDETVKLAKEKGITRSMAAVEIAAKEEGRKIFVLGNAPTALYKVMEMKSEGRLDLD
                     AVIGVPVGFVGAQESKDEVEKTDIPYIISKGRKGGSNLAAAIVNAILYTM"
     gene            19348..20574
                     /gene="cbiD"
                     /locus_tag="KRH23_002628"
     CDS             19348..20574
                     /gene="cbiD"
                     /locus_tag="KRH23_002628"
                     /EC_number="2.1.1.195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_process: GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-5B (C(1))-methyltransferase
                     CbiD"
                     /protein_id="HHS5225906.1"
                     /translation="MEEYVYIDGKKYRRGYTTGSCATGASKAAVYMLITKNRINTINI
                     DTPKGIPLLLKVDNINISDTFVECSIKKDGGDDIDATHTMDIYARAEIVAKNDKNKGY
                     LTLKDIDSLSTNSECKSELYKFIRVYGGTGIGVVTKKGLSVDVGKPAINPTPLKMINH
                     EIRKLIGDNFEPILGNDKVLKITIFAPQGETVAKKTFNPRLGIVGGISIIGTTGIVEP
                     MSDEGWKKSLSIELQMKKEQGLDKIILVPGNHGEQFIREKLNLDIKYVVRVSNFIGYM
                     IKEAQRIGYKKILMAGHIGKFIKVSAGIFNTHSKVADARSEILVANLALMGARYEFLN
                     KINQCVTTEEAVELINNSEYREVYNILSNKCRERVKQYLNEDSDDIDVEVIIFSMDKS
                     LLGKSDNTDDLVEVFI"
     gene            20571..21179
                     /locus_tag="KRH23_002629"
     CDS             20571..21179
                     /locus_tag="KRH23_002629"
                     /EC_number="2.1.1.289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-7 (C(5))-methyltransferase"
                     /protein_id="HHS5225907.1"
                     /translation="MINIIGLGPGNLDYITKKGENLISTSDVLIGGKRNLESIKNFEG
                     EKIVLDSNLREIIEYINNNKEKQISIIASGDPLIYGIGRYLSKNIDNKMLNVVSGISS
                     LQYIFSKIYVDMNDVYITSSHGKVPDFDYILSHKKVCMVTDSKIGPKQISREIIDRNL
                     NKIIVVGENLSYDNEKITIAKPEEIIRMDNFDMNVVVILDEE"
     gene            21169..21744
                     /locus_tag="KRH23_002630"
     CDS             21169..21744
                     /locus_tag="KRH23_002630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008276 - protein methyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="decarboxylating cobalt-precorrin-6B
                     (C(15))-methyltransferase"
                     /protein_id="HHS5225908.1"
                     /translation="MRNSEFITGKVPITKEEVRAISISKLNLVNAKNLIDIGAGTGSV
                     SVEAAYNYPNLKVISIEKNDDAIELIEKNKKKFNLKNIEVIKGYAPINLGLNVKVESI
                     FLGGTGNNLEEIIEWSKKNLVTGGRLVANFIIIDTFNQTLKLLKKHGFKEIDVCVLNV
                     SKLEKLGKGEYFKPLNPIYIISCEKGENDDE"
     gene            21737..22489
                     /locus_tag="KRH23_002631"
     CDS             21737..22489
                     /locus_tag="KRH23_002631"
                     /EC_number="2.1.1.271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-4 methyltransferase"
                     /protein_id="HHS5225909.1"
                     /translation="MNKVHFVGAGPGDKELITLKGYKLLSNADVVIYAGSLVNPELLE
                     YCKEDCQIHNSAHMDLQEIIDVMREGIENNKSVVRLQTGDFSIYGSIREQVEDLNKLN
                     IDYDCTPGVSSFLGAASSLGVEYTVPEISQSVIITRMEGRTPVPEKESIQSYAKHQTS
                     MVIFLSVQEIEKVVSKLLEGGYPKDTPIAVIYKATWADEKIVKGTLSDIAVKVKENNI
                     NKTALIMVGRFLGEEYNNSKLYDKDFKHEYRG"
     gene            22473..23594
                     /gene="cbiG"
                     /locus_tag="KRH23_002632"
     CDS             22473..23594
                     /gene="cbiG"
                     /locus_tag="KRH23_002632"
                     /EC_number="3.7.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin 5A hydrolase"
                     /protein_id="HHS5225910.1"
                     /translation="MNIEGNIAIICITENGKKLALKINSLVNNCVIYQVKNKKSNLVV
                     EETCVHTVQKKLSDFVGEIFSKFDYIVFIMATGIVVRSIAPYIISKFSDPAILVMDEK
                     GKNVISLLSGHIGGANSLTQYISSLIDANPVITTATDINQKASLDMIAKKLNAHIDNF
                     RESVKEVNSMLVNNKCVGLYVDEGYQVDTRGFKLIESKDELRDSFSNAYIEKLVVVSN
                     KINCIEDIENLNLDNKFEHCYSTQKIIKVIPRDIVIGIGCRRNTDSELMYNSLEEFLN
                     KQNIDIRAINTVGSIELKKDEKAIIELSKILKVPFKTFSVDEISKVDNLFDKSDFVKK
                     NVGVYSVAEPVAYLLSKGNLLVEKHKYKGITFSVGRIKI"
     gene            23591..24316
                     /gene="cobJ"
                     /locus_tag="KRH23_002633"
     CDS             23591..24316
                     /gene="cobJ"
                     /locus_tag="KRH23_002633"
                     /EC_number="2.1.1.131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030789 - precorrin-3B
                     C17-methyltransferase activity [Evidence IEA];
                     GO_process: GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="precorrin-3B C(17)-methyltransferase"
                     /protein_id="HHS5225911.1"
                     /translation="MIYVVGIGPGSKDTMTLEAIKAIEDSEAIVGYKTYIKLIEEFIQ
                     DKEIIQNGMRQEVDRCKQAVEEAKKGKKVAVVSSGDAGIYGMAGLILELISKEDEDIK
                     VKVIPGVTASIGAAAILGAPIMHDFCHISLSDLMTPWEVIEKRLRLAAEADFVICLYN
                     PRSKGRSEHLSKAFKIMGEFKGGDTPVGVVKDVGREKEEKFVCTFENMDFEKVDMTTM
                     VIIGNKSTYINGELMITPRGYTV"
     gene            24313..25065
                     /gene="cobK"
                     /locus_tag="KRH23_002634"
     CDS             24313..25065
                     /gene="cobK"
                     /locus_tag="KRH23_002634"
                     /EC_number="1.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016994 - precorrin-6A reductase activity
                     [Evidence IEA];
                     GO_process: GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="precorrin-6A reductase"
                     /protein_id="HHS5225912.1"
                     /translation="MILILGGTSDSLSICDKINELKNQPYILSVTTDYGRELAQQHAE
                     NVILGKLGKEDMLKFIKDNNIVKIIDATHPYAVEVSKTAITCAKLLNIDYIRFERKSL
                     IEEIDYDNKFIVDTIEEACEIANKIGTNIFIGTGSKNLNRFIEEISDKNLVVRVLPTS
                     EVILSCEKLGLSADNIVAMKGPFSQYINEETYKHYNIDLVITKESGIAGGFLEKVNAC
                     KTFNIPVIIIKRESINYENVFNDINKIKDILV"
     gene            25084..26562
                     /locus_tag="KRH23_002635"
     CDS             25084..26562
                     /locus_tag="KRH23_002635"
                     /EC_number="2.1.1.151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-factor II C(20)-methyltransferase"
                     /protein_id="HHS5225913.1"
                     /translation="MKKALLVVSFGTSYHETREKTIDICEDKIKNSLKSHDFFRAYTS
                     NMIINKIKKRDGIEIDNPIQALDKIYEQGYDEVIIQTLHIICGEEFNKLKEQVDGYSS
                     KFKKIVLGRPLLTHIEDYQEAVEAIKHQIPHMESNEAVVFMGHGTLHESHSAYPALEY
                     MLRDNGINAYVGTVEGYPEIEHVIRRLKEGNIKTVNLMPFMLVAGDHAINDMAGDEED
                     SWKTILEENGFNVRVHLKGLGENSYIQDKFVRHAVKCAENAKFYGIGAGPGDGSLLTI
                     KAVNTLKKLDILYTPESKKGGDSLALSIVSEYLPESVEIKSRHFPMSFDGNEKSLAWD
                     NVAQEIISDVNDGKNVGFVTLGDPMIYSTYVYIMKRILGEVEVETIPGISSFSNIASN
                     QNFPLVMDKEALVVIPCTMEDDKIEYALQNYNSIVLMKVYKNFKEIIKKLEKYDLIEH
                     AILVSNSSQESENVFTDLKEAHLEDKISYFSTILVNKDNKIK"
     gene            26592..27497
                     /gene="hemC"
                     /locus_tag="KRH23_002636"
     CDS             26592..27497
                     /gene="hemC"
                     /locus_tag="KRH23_002636"
                     /EC_number="2.5.1.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004418 - hydroxymethylbilane synthase
                     activity [Evidence IEA];
                     GO_process: GO:0033014 - tetrapyrrole biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylbilane synthase"
                     /protein_id="HHS5225914.1"
                     /translation="MNIVVGTRGSNLALIQTEWVINELKKKYPEISFEIKIIKTKGDL
                     IQNVSLDKIGDKGLFVKEIEQQLLDGKIDIAVHSMKDMPSYLADGLKFAHTPKREDPR
                     DVLILREGYKNLDDLPHGAVIGTGSKRRKFQLLKQRPDLNIVQVRGNVETRIRKIKDE
                     NMHGIVLAASGIIRANLQDKISSYLPVDVVIPAPAQGALAIEIRSNDSTIEGIVNSLK
                     DENTEIQILAERGFLDGVNGSCHIPMAAYCEIIQDKIHLTGLYGDSEGKKVVIKSIDG
                     DISSPRELGLKLAKLVLKEYENYEG"
     gene            27487..28986
                     /gene="cobA"
                     /locus_tag="KRH23_002637"
     CDS             27487..28986
                     /gene="cobA"
                     /locus_tag="KRH23_002637"
                     /EC_number="2.1.1.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004851 - uroporphyrin-III
                     C-methyltransferase activity [Evidence IEA];
                     GO_process: GO:0019354 - siroheme biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen-III C-methyltransferase"
                     /protein_id="HHS5225915.1"
                     /translation="MKGKVYLVGAGPGDYKLMTLKGLECIRKSDVIVYDRLANSSYLR
                     EAKPDCELIYVGKASSNHILPQEDINRIIAEKAKEGKIVTRLKGGDPYVFGRGGEEAE
                     TLVDEGIEFEVVPGITSAIGGLCYAGIPITHRDHASSFHVITGHLKGDDSGELNWNAL
                     ANNKGTLVFLMGISNLEKISENLMKEGKDKDTPVALISWATRYNQRVVTSTLENVYET
                     AIKEEVKPPTLIVVGSVVGLREKLNFFESKPLFGKSIAVTRSRNQNSVLVEKIMDLGG
                     NPIEIPTIKVEKIQNNINLENEIKNINKYNYLILTSKNAVEIFFEKIYEMNFDLRILS
                     NLKVCAIGSATSNELKKRGIIADIVPKKFVAESLYEELAPILNDDDNILIPRAENARD
                     YLVDKLKAICEVTEVHIYRTVIDEEKKGEILDILNSNDIDYITFTSSSTVNNLVEIIG
                     KENIKILEKIKTLSIGPITTETINSLGIKLYKESATSTIDSLVDLIIKN"
     gene            29003..29968
                     /gene="hemB"
                     /locus_tag="KRH23_002638"
     CDS             29003..29968
                     /gene="hemB"
                     /locus_tag="KRH23_002638"
                     /EC_number="4.2.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0004655 - porphobilinogen synthase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0033014 - tetrapyrrole biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="porphobilinogen synthase"
                     /protein_id="HHS5225916.1"
                     /translation="MLRRPRRLRASKAIRNLVRETKVNVEDLIYPLFVVEGENIKEEI
                     KSLPDVYHLSIDMLEDEIKEISELGIEHIMLFGVPDEKDECASQAFNDNGIVQKAIRK
                     VKEINSDINVITDVCMCQYTSHGHCGILTDTGYVDNDKSLEYLAKISVSHAKAGADMV
                     APSDMMDGRIQAIREALDENGLENVGIMAYSVKYASNYYGPFREAAHSAPSFGDRKTY
                     QMDPANSNEAIIETELDILEGADILMVKPALSYLDIIRRVKDNFDLPLAAYNVSGEYS
                     MLKFAVKEGLLNEDVILESITSIKRAGADIIITYFAKDIAKLLKK"
     gene            30121..30699
                     /locus_tag="KRH23_002639"
     CDS             30121..30699
                     /locus_tag="KRH23_002639"
                     /EC_number="1.3.1.76"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004325 - ferrochelatase activity
                     [Evidence IEA];
                     GO_function: GO:0043115 - precorrin-2 dehydrogenase
                     activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0019354 - siroheme biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="precorrin-2 dehydrogenase/sirohydrochlorin
                     ferrochelatase family protein"
                     /protein_id="HHS5225917.1"
                     /translation="MLYPINLKLDELDVVIIGGGEVAYRKCKNFLEFNKNVTIVSKQI
                     LNKFYDLKGNIKIIKDDYKEIYIKDASVIIAATNNRELNMEIGLYCRAKNKLVNVVDN
                     IEISNFTVPSYIKRGDLLISVSTGGKSPSLSSKIKKEIEERYTEDYEEYLNVLGDIRK
                     KVIKKYEDKSKRKDVLNMLVTLDLEELKKFDI"
BASE COUNT        12449 a         3058 c         5674 g         9566 t
ORIGIN      
        1 cagcttttat tggtaaagta ttacatatat aattaaaata tactaaaaat tgaactatat
       61 attttattat tataaaatat ttatattaaa ttgtggaatt aaaatatact aggatataaa
      121 attcttaaat aaaaagaaaa ggttgttttc ataaaaaata ttttttatac cactttaaaa
      181 aacacaataa taacactgag ggaggtgggg atatgagaga acgcattatt cttgaaacat
      241 taaaaaatag tagtggttat ctaaacatag attattttgc agataagttg ggggtatcta
      301 ctcgaactat cagaaatgaa ataaaaaaga tagaaactat aaaagaatgt aatggtttta
      361 aattagaata taagtctaaa ttaggatata ttctaaatat taaagaccaa gataaattcg
      421 agcattatct aagaaactta ccctcagatt tagttgaaaa tccagaacaa cggttggagt
      481 ctataatagt agagctttta gtaaatgaag gttataaaac tatagaacag ttaagtaaaa
      541 aatttctagt aagttcatcc caaataaaaa atgatttaaa aaagatagat gaaaagataa
      601 aggatacaga attaaaacta gagcgaaagg ctcattatgg aattaaaata gaaggttcta
      661 taaaagaaat tcaaagtata ttggtggata gttattttag agggaataga aatataacag
      721 agtacaggaa taagtttata gataatttaa aattagctaa tattagaagt acaataaaaa
      781 atgtacttaa tgaacatgat ttagaagcaa atttaacaga acttgaggaa atattagcac
      841 aaattattat attgtatata agagttagta tgagagtagc gggaaatgct agcgatttaa
      901 aattatatac agaagattta attatagata aattattaga taaaattttt agagataaaa
      961 aatataacct taattatgat gaaaagtatt atttaaagga gcttataaaa ctaaagacta
     1021 aagataagaa agccactata aagaatattg ataagaataa acttcaagat attatgttcg
     1081 aattttttag agagatagat aaaaaatata actctaattt tttagaagat aaagagttct
     1141 ttaacttatt ttacttacat attgcatgtt taatagaacg tataaagaag aaccacaaga
     1201 taataaatcc tttttcagtt aaaataagtc aacagtatcc aactgttttt aatttatcta
     1261 ttcaattttc aaaaatcata gaaaatgagt atcatataaa aataagtcaa gatgaaatag
     1321 ggtttatagc tactcacatt gctgttcctt ttgaaaagag agaagaagct aattttaata
     1381 aaaaatataa aatagcaata atatgctctt ctggtggagg tagtgcattt ttgataaatt
     1441 taagacttaa agaaattttt ccaaatgctg agataagaaa tttttcatta ctagaagaaa
     1501 aagctgtaat agaatttgca ccagatttga ttttttcaat aacaaatctt ttatttgaaa
     1561 taaatgctcc agttatactt ataaatgaaa ttttagacga attggattat ttagatatta
     1621 aagaaagtgt tagatttgca gaccatatag gaaatatatc aagcccaaaa caatatatat
     1681 taggtctatt tgataagaat cactttaggt gtataaaaga taaagctaag tataaggata
     1741 tccttgatag tatgtcaaaa tgtatagttg acgagggagc ttgttctcca acctatccca
     1801 aagatgtatg ggaaagagaa agctatttga gtactattta tacaaatggg gtggctatac
     1861 ctcatccaat cgagatgaca ggaaacaaaa atataatatc agtagctttg atacaaactg
     1921 atattattta tgaaaatagg gtgcctaaaa ttattttcat gatttcatta ataaagggaa
     1981 atttagaact tcataagcaa atatctaaat atttaagtaa gattatggca aataaggata
     2041 tggtagacat gctaaataag tcacaatctt atgaagagtt tatgtataag ttaaaaatct
     2101 atctgggagg ttagacatga atatagagtt ttttaagagg ttgtcagaag cagatggtat
     2161 agcatctaat gaagaagagg ttagacatgt tttattggaa gaactaaaag cttatagtga
     2221 taaaattatc tgtgatgggc tagggagtat catcttttct aaaataaaag atgagagtgc
     2281 accaaacgta atgatttgtg ctcatatgga tgaagttgga tttatggtga gaagtataga
     2341 caaacttggt atgattcact taataacaat aggaggagta aaacctcttg cacagtttgt
     2401 acaaaaagtt agaattacaa caaaagaagg gaaaaaaatc cccgctgtca taaatgctac
     2461 atataataat ggtaaggctg aaaatatata tgcagatatt ggagcatata cagaagaaga
     2521 tgtatataac ctagggatta atgttgggga tatggtaaca tatacaacaa gctttgagga
     2581 atttacttta ccagaccgat tagtgggaaa ggcttttgat gataggatag gatgttttgt
     2641 gatgggagaa gttttaaaag aacttaggaa agaaaatcta aattgtaata ttcactttgc
     2701 ggctacaagt agtgaagagg ttggaataag gggagcaaag acatcaacac agttaataaa
     2761 tccagatata gtatttgtaa tagatgtagc atgtgctaaa aatgagtttg tgagagacta
     2821 tacaaatcag aaacaaattg ataaaggtgt aatgctaatg catagagata ggactctagt
     2881 ccctagtaga aaaatgatag attatgtaat ggaaattgct gataaaaata atataccact
     2941 tcaacatgat atgtttgaat caggtgggac tgatggagga gaagcacatc tcgtaaatga
     3001 agggaaacct tgtgtagtaa cttgtgtacc agttagatat ggtcattgtg cattttcaat
     3061 agtaagtaat aaagatttgg agaacattat aagattgtat acacagttaa ttttaaattt
     3121 tgatgaagaa caatataaac atataagaaa ttttatctaa aggagaataa gaaaatgtca
     3181 acagaagtac aaataatgga acttatatca actgcaggag agagtaaatc gaaagctttt
     3241 gaggctttaa aaaaagtgaa gtcaaaagat tttaaaggag caaaattgtt aatagaggag
     3301 gctcgtaaaa tagatattga agctcacagg atacaaacag aattaataac tcaagattta
     3361 aatgaagatg ttgaaagtcc agcaatgagt cttttaatgg tacatgctca agaccactat
     3421 atgacttctc agctagcaaa agacttgata gaggctttga tatattgtct cgataagtaa
     3481 ttgtaatgta gaaatagatt atttatgtaa aaattctttt aaaagtttag atacttttaa
     3541 gagataataa aaatacaaac tttaggagga attattatga aaatattatt atgttgtgca
     3601 ggtggatttt ctactaatat gttaatgcaa aatatgaaaa aggtggtaaa agagagtgct
     3661 aaactcaatg aaaaagattt tgagtttaca gctataccag cagattcaat agaaagtgaa
     3721 gttgatgatt gggatatagt acttataggt cctcaaatag ctcacaaaat agacttctta
     3781 aaaggaatat tagagccaaa aaataagcct tttgcagtaa tagataaaga tgtatatgga
     3841 aaaatggatg gagctacagt tatgaagttg gcattaataa cttataagaa acatcaatta
     3901 gctcaaggat aataaaaata atgagggaaa agggagatta gatatgtttt caaaatttga
     3961 agcatttatg aatagagtat ttatgccttt agctcataag gttgacaatc aacgtcacct
     4021 tggttctata aaggctggta tggttgctat gacaccattc acaatattag gaagtatatt
     4081 tgcaatactt ccagcacttc caaatatgct tggagaaaat aatccaataa gcaaattcat
     4141 acttaacaat tcagcaatat tggatttacc agtaagtctt tccataggtt taataggatt
     4201 atatgcttgt atgtgtattg cttttaatct ggggaactac tataaattat atataccagg
     4261 ttgtgttgca ctatcaactt tttctttttt attcctagta gcctcattta caccagatgg
     4321 agctttagaa ataggaaatt taggagctaa agggctattt acaggtatga tagcagggct
     4381 tggttctgtg gagttatata atttttgtaa taagaagaat atcacaataa aaatgccaga
     4441 aaatgtacct gattttgtat ctaggtcttt tgaattaata cctactacta taatagtttg
     4501 tggaactttt atagttgctc gttttatttc attaaaagta tttggagaat tacctccaca
     4561 gatacttact caatttttat ctccattagt aggaagtatg gataacccat ggtcagttct
     4621 tgcacttaac tttgctatat gtactatatt cttttttggg atacattcat cagtatttag
     4681 tcctataact agacctataa tgattacatt tatagctgaa aacatagcag ctatgcaagc
     4741 tggagaaaca atacctcatt tctttacagc aggagcttca agtgcattct ttggatttac
     4801 aggatgtgga attagtatag gttgtgtaat tgcatgtatg ttatcaaaaa atgcttccta
     4861 taagaagatt ggacgtgtat cattattccc tgcattattt gggataaatg aaccaatatt
     4921 atttggagca ccgataatat taaatccaat aatgtttata ccacatgtat ttggtggagc
     4981 tataataggt acactaccaa tgttttttat gcactgggga tggttagcaa agccagtatt
     5041 tgaccctcca tatgtagggg tattcttaga aggattttta actaatggag attggcattc
     5101 tatattagca aatgcattgc aattagtatt agcagtttta ttatattggc cattctttaa
     5161 aataatggaa cgtcaacaaa ataataaaaa acaaaaagaa gaaactaaga atatattctc
     5221 taaagaagaa gaagacttat tggatgattt aggattggat ttctaatatt ttgttatgaa
     5281 taatacaatg gagagattag tatccttaat ctataaaaga ggtgttgacg ctcttttgat
     5341 taaagcaaaa aatactaaaa gatatatagg agctttatca ggtagtggtg tatatgtgct
     5401 tgttactaag gataaaaatt atcaaattct agatggcaga tatattgatg aagcagataa
     5461 aaaaacgact ggtttcataa aaaggattgt atctcaaggt tcttatatac caactataat
     5521 tgagttatta aaagaattaa atataaaaaa gttagcaata gaaaaccaag ctatgagtat
     5581 acaagagtat ctttcactaa aaaatgaagg ttttgaaatc aatttaataa caaatgaatt
     5641 atggaagcta agggctataa aatctaaaga agaaattgaa tttattaaaa aggcttgtga
     5701 gattacagat gaagtatttg atgaggttat ttctgaaatt aaaaaagata tgactgagct
     5761 agaagtatca gctctaattc agtatcatgc attaaaaaaa ggtgcaagtg gaatgtcttt
     5821 tgaaacaata gtggtatcag gagaaagagg tgcaatgcca catggaagac ctacaaacaa
     5881 aaaattgaaa gtgaatgaag ctataacaat agattttggt gttgtttatc aagggtatca
     5941 atcagacatg actcgtacaa tatctatagg taaacctcct aaaattatta aagagatata
     6001 tgatgtagta ttggaagcac aattatctgc aatagagtca ataaaggaag gaactagggc
     6061 aagtgatgtt gacaaagtgg ctagaaaaat tatagataaa catggatttg gcaaatattt
     6121 taatcatgga ctgggtcatg gtataggtct tggagatggt gaagtcccca ctttaaatcc
     6181 aaatagtgaa gatatattag tggaaggaat ggtaatgtct tgtgagccag gtatttatat
     6241 tccaaatgta gggggagtta gaatagaaga tgacattgtt ataatagatg gaaaaggtgt
     6301 tccactcaat aagacatcca aagagtttat aatattagga gagtaaaatt atgaaatata
     6361 attttaataa agtattaaat cgtaaagaag gaaattgtag aaaatggagc aaccatgtga
     6421 ttaaagaaaa attcggctta aatgaagatg caattcctat ggatttagct gatatcgatt
     6481 ttgagtgtgc tcctgctata aaagaatcta tcttaaaaag agcatcagta ggagattata
     6541 gttatacttt tataggagat gacttctatg atgcgattat aaattggaat aaaagaagat
     6601 ttgatgtata tatagaaaag gattggataa aattaacttt tggtactgtt tcaacccttc
     6661 attatatagt ccaagcatat actaaagaag gagagggtgt attgataaat acacctgctt
     6721 atgacccttt tgcagaggct gtagtaaata ataatagaaa gttgtgttgt agctcattaa
     6781 aattagataa caatagatat tatttagatt tagaggatat ggaaaatcaa atgaaatacg
     6841 agaatataag attgcttata ttctgtagtc cacaaaatcc atcaggtcgt atatggacaa
     6901 aagaagaact atatcaagtg tcagagttat gtttaaagta taatgtaatt ttggtaagtg
     6961 atgaaattca tagagatata atatttaaag attatagatt tgtatcttta tggaatgctc
     7021 atccagaaat ttataaaaat agtataatct gtgtatctcc taataaaggc ttcaacttag
     7081 gtggattaaa aacatcatat gtattaataa gagatgtaaa aattagggag actttattag
     7141 aaaggctaaa aagtaattca ataacttctc caaatgtatt tgcaatacca gcaatagttg
     7201 cagcatataa tgaaagcgaa gaatggctag atgctatgac tagttatgta gaggagaatt
     7261 ttgaaatagt ttatgatttc tttgaaacta atataccaaa agctaaagtg atgaagtcag
     7321 actcttcttt tttagcctgg atagatgtaa gagaagtatt tagaaatgaa gaagaatcta
     7381 aagaattttt tagacatgca aacttaacta tggtagttgg aagttatttt gtgaaagatg
     7441 gagatggatt tattcgtatt aatgtggggt gtcctagaga aacattaaat gaggctctaa
     7501 atagaatcaa aaaaacgtat ataagtatgt attgttaaat cataaaaaaa gtatctatgg
     7561 tttatataaa aacatattat ttagttatca aatattactg gaattttgta ttccagtaat
     7621 attttttgat taaggaatat tattgaggaa tattaaataa tattatttca tacccttata
     7681 ttaacttata taaaaatatt ttattatttt gggaacgggt tagctaacct ttatctagtg
     7741 tatatttata ttgtaagaag cagtaaaaac ttttccttta ctaagtttat taataaactt
     7801 cttatcttta taaattttgt tagaatttat actatcagca agaccatacc aaggttctat
     7861 acataaaaaa ggagcagtag aattagtttc actataataa ggagtccaaa taccaactag
     7921 agggaaatct tccatagata tagttacata tttactacca tcattattac atatagacac
     7981 ttcatctatg ttggtgtata tcaaagcatc attcttgaat acttctggat ttaactgtaa
     8041 gttttttaat tttccaatag gtattatatc atctgtaaaa gaaccattta aattgatttt
     8101 ttctacatca tttttacttt taaactcaag gtagtgttta gaaaaatcat tttgtttgta
     8161 aaaaggaagg ttgaatgcag gatgtccacc tatagaaaag aatatatctt tagaatcagt
     8221 attttttaca atccattcta cctcaatact attatcattt aatgtatagt ttatgattag
     8281 ctcaaaagaa tatggatact tctttaaagt agattcatta tctgttaatt tataagttac
     8341 aaaggtatct cctttatcta caatctcaaa gtccatatct ctagcaaacc catgttgagt
     8401 catgctatat aaattttctt ctattattgt ttcattatca aaaagtttac ctactatagg
     8461 gaacaatata ggtgattgtc taccccaata ttttttatta ccatcccaaa gaatgttttt
     8521 gtcgtatttt ttagaaaata ttttagttag ttcagcacca aaactgcttg attcgataat
     8581 taaattttca ttttgtaata tattcattta aaatctcctt tattatattt tatgagtata
     8641 ttatactata aagtataaag attattaaat tttatttgat attatatttg aaaggtagat
     8701 tttagtatat tttgaaaatt ttgttttgaa aatttgggat tatttaagaa attttgtatt
     8761 ataaatagaa ggaaatagat aaattgtata gaataaaata tattaagata agttaataat
     8821 gttaaatggg aagtgagttt atggaaaaac caaatacaaa agttgttaac tttcaagagt
     8881 ataaagacag aaaaaaccaa agagaagtaa atagagacga acttttaaag cttataaaaa
     8941 aaattgtgac ttcaaaatag ggagttgtta aactccctat tttaatgggt ttcataatga
     9001 ctaagacatt ctaagtccat ctatataatc tttgaattgt gagaaatctg attcactact
     9061 taactctata gtttctgagc cttccgtata aaaattctta agatagatag tataattatt
     9121 atcaacacaa tcatgataaa tacatctata tccatcttca tacaaacttt ttaacttaga
     9181 aaaatcatcc acaatatcat ctccttaaag ttcttttaaa tatattttta caaaaatcat
     9241 ctaattgtat gcaaattgat aatgtaaaat aaaggaaata cagataaaat gtagaataat
     9301 ttttatatgt atgtaaaaat aaaaataaaa agttgaaatt tttagaaaat aagagtattt
     9361 tttatctaaa aagataattt aaaaaataaa aaaatgttgg gaggataaaa atgagtttat
     9421 tagaaagtat atcaaaaaac atatattctc tagataattc ttctattgaa aaaacaaagc
     9481 agagattgga caggcttata catccaactg gaagcttagg aaagatagaa gatatttgca
     9541 tgcaattagc aggaatattt ggcaatgaaa attttgatac aagtaaaaag gttataattg
     9601 cttttgctgg agaccacggt gtatatgaag aaggagtagc acctgaccct caaaatataa
     9661 caaaattaca atttccaaat ttttcgaaag gtctatgtgg agttggagta ataagtaaat
     9721 ttgtaggggc agatgttgta gctgtagatg tgggaataaa ctgtgatgaa aaactggatg
     9781 gagtgttaga ttacaagata agaaaaggga catcaaatat ggcaaaaggt ccagctatga
     9841 gtaaacaaga agctattaga tgcttagaga taggtattga aatagcagag cagtgtatag
     9901 aaaaagatta taaggttatt ggtattgggg agatgggtat agcaaatact actccaagta
     9961 cagcaataat atctgtaatt tcagggtgtg acccgttaga agttactggt ataggtgcag
    10021 gtcttaagaa agaaagacta aagcataagg ctgaagtaat tagaaaggct attgaaatta
    10081 ataatccaaa tccaactgat ggagtagata ttttatctaa agtaggagga tttgaaatag
    10141 gctcaatggc aggtgttata ttaggttgta gtgctaatag gattccagta gtaattgatg
    10201 ggtttatttc ttatgcagca gcattaattg catataagat aaatccaaaa actagagaat
    10261 atatgatagc atctcattta tcagcagaat caggaactaa aagagcatta gacatattaa
    10321 aattagaccc tctattaaat atggatatga gattaggtga gggaagtgga gctgctttag
    10381 catttgatat aatagaagct tcaaactata cttataaaaa tatggcaact tttgatgaaa
    10441 ttgacatggg aagataaata taaaaattta atatgtagga gtgttttgat gagtaaaatt
    10501 attctagtaa caggaggagc taggtcaggg aagagtaact ttgcagaaaa actatgtttt
    10561 gacagaaata ataatacagc ttatatagca acctctattc catttgatga tgaaatgaaa
    10621 gatagagtaa aaaaacatca agagaataga cctagaaact ggaatactta tgaaatatat
    10681 gaagatatat attccataat taaggagata tataaagaac atgaaactgt tatactagat
    10741 tgtgtaacat tattagtaaa taatctaatg tttgaacaca atctaaatat agaagaatct
    10801 agtcaagaag aaataaacaa attagaacaa tacataaaag aacaagttgt caaacttatt
    10861 gaagaaatag aaaaaacaaa tctatacttt gtatttgtaa cgaatgagtt aggtatggga
    10921 attgttcctg ggaataaact tagtagaatt tatgctgata ttgtaggtcg tataaatcaa
    10981 tatatagctt cgaaaagtaa tgaagtttat tttgtagtta gtggcatagc tatgaagata
    11041 aaggagtagt atgcaattat gaaaagattt attttaatac tacagttttt gacaaggata
    11101 cctataaaat taaatgtagg atttgatgat gaattttata agtcaatagt atattttcca
    11161 cttgtaggtt ttgttatagg tatattatcc tatttaatag gatggatttc tatgctttta
    11221 tttgaaccat ttatagcttc tataataata actctagctg gtgtcttaat tactggagga
    11281 cttcatatag atggattagg agatacattt gatgcaatat atagttatag ggataaagaa
    11341 aagatgcttg aaataatgaa agattcaaga ttaggtacaa attcacttct agcaattatg
    11401 tttgtacttt tattaaaggc tggattcgtt tacgatataa taagtaataa ttcattgtgg
    11461 gttataattt ttatgccaat gattgcaagg ttaggagtaa tgttattgac atataaaact
    11521 gtgacaccaa gagaaaaagg aatgggaaat ttatttatag gaaaattaac tacaagtatg
    11581 ttaataactg ctataatata cacattattg atagttgctc ttattactaa atttatattt
    11641 ttattaccta atatagtgtt gattaaagta ttaggttcgg ctatagtagt ttttgtattt
    11701 ataatattat tcaaaaaaca tatttataaa aaaattgatg gagtaacagg agatatatta
    11761 ggctgtggaa tagaactttc agagcttgta tatttaattt acatatattt gttaattttt
    11821 gtgttttttt aaactaaaaa gtggtgataa tatgataaga ttaatattaa taagacatgc
    11881 actgacaaat gataataaaa aaggaaaatt atcaggccat agaaatagtt gtattagtga
    11941 agagggtaaa ctacaaataa ataaaattac tagatatctg agtaatgaaa atatagataa
    12001 gatttataca acaccatcta cacgtactaa agatacaata gaaaaaatat caaaattgaa
    12061 attattagaa atagaagaaa aagaaacttt aagagaaatt agttttggag actttgaagg
    12121 aataactttt gaagaaatta aaatcaaata tcccaatgag tttgaaaaaa tgataaaaga
    12181 aggcaacaat tatagatatc caaatggaga aagtttgata gattcttata aaagagtggc
    12241 aaaagaaatt gataatataa ttttagaaaa tgatattgat ttagatacaa agacaatact
    12301 tatatgttct catgcaggaa caataagaaa tataataaca catttgattt ctggtagtta
    12361 taagtatcac tggaacttta aaattgataa tgcatctatt acagttttag aaattgatgg
    12421 tggatttgct gtgatagata aaatgaattt tacagacttc atataattta atcaaaacca
    12481 aacattacaa tctgtgtttg taatatatct gtaaaattag caatgaaaat agaatattag
    12541 attaaaatta ggttcttaat tagatgttaa aagggaaaaa ggttagatgc ctttgcagcc
    12601 cccgctactg tgaaaccaac gaaactataa ataccactgt cagtttgatg ggaaggttat
    12661 agaagtagga tgaagttaag ccaggatacc tgcctaattt aatttaaaac aagaggtctt
    12721 cggggtgaaa gatttttaat taatatatat aaaagtccta tctttagaag tattagggct
    12781 ttttttaatt tgttttttag taaattttaa caaggaggga tggaaagtgg ggaaaaaaat
    12841 aatgctacaa ggaacagctt caaatgtagg taaaagtgtc ttagtagcag gtttgtgtag
    12901 aatatttaag caagatggtt atactgttgc tccttttaag tcacaaaata tggctttaaa
    12961 ttcttttata actaaagaag gattagaaat gggaagagca caagtatttc aagcagaggc
    13021 tgcgaaaata gagccaatag ctgatatgaa tccagtttta ttaaaacctt ctggaaataa
    13081 taaaagtcaa gttattgtaa gaggtaaagt tgtaggagaa atgccttctt ctaagtatca
    13141 tgattataaa ttggagttag taggtgtgtt gaaggaaaca tttaatagct taaattcaag
    13201 gtatgatatt gtagttatgg aaggggcagg aagtaatgca gagataaact taaaagatag
    13261 agatatctct aatatgggta tggcagaaat agctgatgca cctgtaataa tagtcggaga
    13321 tattgataga ggaggcgtat ttgcctcatt agcaggaaca atgcttttat taaatgaaga
    13381 tgagaaaaga agagtaaaag gtgtaataat caataaattc agaggaaaaa aagagctttt
    13441 acaagatggt gtaaagatgc tagaagacat cataaaagta cctgttatag gagtagtacc
    13501 ttatacagat ataaaaatag aagatgaaga cagtgtaact acgagattta agaaaaaaat
    13561 gaataaaagt gatatacaca tagaaataat tagaacccca catatgtcaa attttacaga
    13621 ttttaatata tttgagacac aagaagatgt aagtattaga tatgtagact atggagaatc
    13681 tttaggaaat ccagatatat taataatacc tggaactaaa agtactatag acgatttaac
    13741 atatataaga aaaagtggtc ttgaatcgca aatcaaaaat ttacatagtc aaggtaaatt
    13801 gatatttggg atatgtggtg gataccaaat gttaggtaaa aaattaaaag acccttatca
    13861 tgttgaaagt gaaattgaag aagttgatgg aataggtctt ttagatacag aaacaacgtt
    13921 tgagaaagaa aagactacaa cacaagtaga agctactatt gttgaatgta tcagtgaata
    13981 catgaataac cttaagggaa aaaaagtaaa aggttatgaa attcatatgg gaattacaaa
    14041 gcgaggtaat gatgtaagaa gtttagattt aataactaaa aaacttgata aagaagtgaa
    14101 ttatactgag ggaagtgtaa acaaagaggg gaatgtaatt gggacttatc ttcatggaat
    14161 atttgatgaa ataagcttta caagagcaat tttaaacaat ataagaaaga aaaaaggttt
    14221 aggagaatta gaaagcaaag taaactcttt taatgaattt aaggataaag agtatgataa
    14281 gttggctgat tttttaagag aacatttaga tatagagaaa atatatgaga ttatgaaata
    14341 atgatgacct ttatttataa tttaggtagg aggtgtatta tgaaaaaaat tttaattgcg
    14401 ggtactaata gtggagtagg taaaacaaca atatcattag gaataatgca agctttggtt
    14461 aagagaaata tgaaagtaca gccatataaa gtagggccag actatataga cccttcatat
    14521 cacactttta taactggaag acattctaga aatttagatt cttatatgtt agatgatgaa
    14581 aaaataaagt atatagtaaa taagtcctca aaagatgcag atatttcagt aatagaaggt
    14641 gttatgggct tatatgatgg ctttggaata gatttagata attgtacaag ttcacatact
    14701 tcaaaggtat taaagtcacc tgttatatta gttataaatg gtaaatctat ggcagcatct
    14761 agtgctgcta tggtacttgg atataaggaa ctagataaag atgtaaatat aaagggtgtt
    14821 atagtaaata atgtaaagac taatagccat tatcaaataa ttaagagttc tatagaaaaa
    14881 tattgtaatg ttgaagtatt ggggtatttt cctccaaata acaaattctc tttggaatct
    14941 cgacatctag gattagttcc tagtgtagaa atgaaatcac taagggaaaa attttatacc
    15001 ttagcagatg aaattgaaca ctatatagat attgacagaa taattgaaat atcagaaagc
    15061 gatgaatttg agagtgattt tgattttcaa actttgatag aaaataataa aataaaagaa
    15121 catgttaata ataaatcaat agctatagca tatgataaag cattcaattt ttattataga
    15181 gaaaatatag agcttttaga ggaacttggt ttagaaataa actattttag ccctcttgaa
    15241 gatgcatcag tgccaaatgc agattatatt tatattggag gaggttttcc agaaatattt
    15301 ggaaaagaat tagaagcaaa tgagtcaatg agaacttcca tattagaagc acataacaat
    15361 aatataccta tttatgcaga atgtggagga ctgatgtacc taggtgagaa actattgaat
    15421 caagaagaac aagaatttaa tatggttgga atatttagtg gaattagtaa gatgacatct
    15481 tctttaaaga gatttgggta ctgtattggt gtagccaagg aaaatactct tttatctaaa
    15541 aaaggggaat ctattaaagg gcatgagttt catcattcaa tatttgaaag tgatgaaaaa
    15601 tgtgtatatt caatgagaaa agaaagagat ggaaatatag tagaagagtg gtatggtggt
    15661 tatagtaaag gaaacacttt ggctacatat cttcatactc atttttataa taacttaaat
    15721 tgtatagaaa attttttgaa aaaaggaaat aagtaaatga gtattttatc tatttatata
    15781 ggatatgtga cagacttaat tgtaggagac ccatattctt ttcctcatcc agtgagattt
    15841 attggtaaac ttataaattt tactcaaggt ataataagaa aggtctctaa aaatgatagg
    15901 cagttaaaat ttgggggatt tatattatgg tttataaccg ttggaataac atatttaaca
    15961 acttatgcta tagtgaagtt atttagtttt aatatattat tgagtattgt agtgaatagt
    16021 tttataattt atacaacact agccacaaaa tgtttaaaag acgaagcatt aaaaatttat
    16081 aatgtattaa aaactgaaga tatagaaaaa tctaggattc agctatctta tatagtaggt
    16141 agggatacta ctaatttaag tgaacctgaa ataataagag caactgtaga aactgttgca
    16201 gaaaatactg tagatggtat aattgcgcct atgttttatg catttattgg aggagcacca
    16261 cttgctatgg cctataaagc tataaataca ttggactcaa cagttggata taaaaataaa
    16321 aagtataaag atattggttt tgcatctgct aagattgatg atatagccaa ttatatacca
    16381 gctagaatat ctgtcattct tatgacaatt ggaagtttct ttttaaatta taactatagg
    16441 aactgtttta aaatctctat tagagataga aagaatcata aaagtccaaa ttgtgctttt
    16501 tcagaaggtg cagtatctgg tgctctagga atacaactag gaggtaccaa cgtttatttt
    16561 ggggaaaaag tatataagcc aacaataggg gataagctta gggagataga taaagaagat
    16621 ataattaaaa ctaataaaat tatgtatgca tcttcatttg tatctatgtt ggtatttaca
    16681 ctaatatatg tgttatgtag gatgatttta attaacttaa ttatataaat tattgtttgt
    16741 taacttaagg gggacataga tgaaggattt agggcatggt gccaatgtag atgaaatggc
    16801 aagattatat gggaaaaacc caaaagaaat aattgatttt agttcaaaca taaatccaaa
    16861 tgtattacca aatttagaga gatacatttt aaaaggatta gaagagtgta ggaattatcc
    16921 agatataaat tatacaaact tgagagaaaa tatatcaaaa tatatagata taaatccaga
    16981 ctttataata cctgggaatg gtgcaacaga agtgatttat ttgcttatga agagtattaa
    17041 aaaaaaattg gctataataa atccgacttt ttcagagtat agaagaagtg ctgagttaaa
    17101 taatttagat attatagact tagagttaga tttagaaaat aactttaaac ttaatataga
    17161 tataataaaa gaaaatataa aaagatttga tagtttattt atatgtaatc ctaataatcc
    17221 tagtggtaat gttcaagatt taaaggaact tgttcattta ctagataaac ataataaggt
    17281 attaataatt gatgaaactt tcatggaatt tgttgaagat gaaagtaaat atagtttggt
    17341 taaatatata gaatcaaata aaaatatatt tataattaaa gctgtgacta agttttttgg
    17401 tatgcctggt ttaaggctag gatatggtct tacaagcaac actgaaatta tgaacaaaat
    17461 ttatgaacac aaagagccat ggactatcaa ttcttttgca gatatactat ccaattttat
    17521 ttttgaagat aaagagtata ttaaaaatag taaagaatat tacatagaag aaagaaaata
    17581 tatgttacaa gagttgagaa acataagaaa tataaaggtc tatgatacag atgctaattt
    17641 tatcttgata agaatatata aaaaaacaac caaagaattg aaaaaagatt tgtttaagca
    17701 aggaaacata ttagttagag atgcgtctaa ttttatagga ttagatgata gttttataag
    17761 agtggctata aaatctcatg aagataacaa aattcttata gaaaatatga aaaatttatt
    17821 gggtgattaa aatgaaatct tatggaatat gcccagcatc ttgtggagaa tttgtacaag
    17881 gtataattga tgatgaagaa tatttatgtt catatgcaat agatatgtat tctaaagtgt
    17941 atattgaaga aaaattagta gatataaatt tagggagata taagtcaagg ttagcaattg
    18001 aaaaggtatt tgaaaaattt aatttaccta aaaaatatac taaaaatatt tctttaaata
    18061 taaatagtaa aatacctgtt ggaaaaggaa tggcaagttc aactgctgat ataggagcta
    18121 ccataaaggc aacattatca ttgatagata aagatttaag tagtgaggag atttctaaat
    18181 tagcagcaga aatagaacca acagattcta tatttataga taaaaatagt atatttaatc
    18241 ctctaaatgg aactgttata aaatacctag gaaatctgac caatgcgaaa gttgtaatac
    18301 ttgaaccaaa caaagtacta gatactatga aaattagatt gaggcaagat tataataaat
    18361 taaaagtaga aaataaagaa gtaataaaaa aatcatttgc tcttttagaa gaaggattga
    18421 aaaaaaataa tttatctcta gttggagagg cttgtacttt gagtagttta gcaaatgaga
    18481 atatagaaaa aaaagagtat ttaaatgaaa taataaaaat atcaaaaaaa tatggagcat
    18541 atggagtaaa cattgctcac agtggaactg tagtaggtat tttaattgat aagtctatga
    18601 atgataaaaa gatgatagat gccttatgtg aatctaacat aaattctgtc tataataaaa
    18661 tttatacaca aaacataatt aatggaggaa ttaaggggga aatagaatgg aatacataaa
    18721 gaatcctatg aaaatagaag aaaaaagttt tgaattgata caagaaataa tagacgaaat
    18781 tagaccagat tataaattta agaataatat cgaagaaaaa ataataaaaa gagctataca
    18841 tactactgct gattttgatt acttagatat attaaaaata tcagaagaag cagttgatag
    18901 tataatagat gcattaaaaa ataatgcaag tatttatact gatacaaata tggctcttag
    18961 tggtataaat aaaagaaagt tagaatcatt aggatgtaag tataaatgtt tagtggcaga
    19021 tgatgaaact gtaaaattag ctaaagaaaa aggaattact cgttctatgg cagcagtaga
    19081 aattgcagct aaagaagaag gaagaaaaat attcgtttta ggtaatgctc caacagcttt
    19141 atataaagtt atggagatga aatcagaagg tagattagat ttagatgcag ttataggagt
    19201 tcctgtaggt tttgtaggag cacaagaatc aaaagatgaa gttgaaaaaa cagatatacc
    19261 atatataatt tctaaaggta gaaaaggtgg cagtaattta gcagcagcaa tagtaaatgc
    19321 tatattatat actatgtagg tatctatatg gaagaatatg tatatataga tggaaaaaaa
    19381 tatagaagag gatatactac aggttcatgt gcaacaggtg catctaaggc tgctgtatat
    19441 atgttgatta caaaaaatag aatcaatact ataaatatag atactcctaa ggggatacca
    19501 ttactactaa aagttgataa tataaatatt tctgatacat ttgtggaatg ttccataaaa
    19561 aaagatggtg gagatgatat agatgcaact cataccatgg atatttatgc aagagctgaa
    19621 attgtagcta aaaatgataa gaacaaaggg tatcttactc taaaggatat agatagttta
    19681 agcaccaata gtgagtgtaa aagtgagctc tataagttta ttagggttta tggcggaact
    19741 ggtattggtg tggttacgaa aaaaggtctt agcgtggatg ttggtaaacc tgctataaat
    19801 ccgactccac ttaaaatgat aaatcatgaa ataagaaagc ttataggaga taattttgaa
    19861 cctatacttg gaaatgataa agttttaaaa ataacaatct ttgctccaca aggagaaact
    19921 gtagcaaaaa aaacatttaa tccaagatta ggtatagttg gaggaatatc tataataggt
    19981 acaactggga ttgttgaacc tatgagtgat gagggttgga agaagtctct atctatagaa
    20041 cttcagatga aaaaagaaca aggcttagat aaaataatat tggttccagg aaatcatgga
    20101 gaacagttta taagagaaaa attaaactta gatattaagt atgtagttag ggtaagtaat
    20161 tttataggct atatgattaa agaagctcaa agaataggat ataagaaaat cttaatggca
    20221 ggtcatatag gtaaatttat aaaagtatct gctggtattt ttaatactca tagtaaggta
    20281 gcagatgcta gaagtgagat attagtggca aacttagctt taatgggagc tagatacgaa
    20341 tttttaaata aaataaatca atgcgtaact actgaagaag ctgtagagct aataaataat
    20401 agtgaatata gagaagtata taatatatta agtaataaat gtagggagag agtaaagcaa
    20461 tacttgaatg aagattcaga tgatattgat gtggaagtaa tcatattttc aatggataag
    20521 tctttattag gtaaatcgga taatacagat gatttagtgg aggtctttat atgataaaca
    20581 taataggtct aggacctggt aacttagact atataacaaa aaaaggtgaa aatttaattt
    20641 ccacttctga tgtattaatt ggtggtaaaa gaaatttaga gtctataaaa aattttgaag
    20701 gagaaaaaat agttctggat tctaatttaa gagaaattat agagtacata aataacaata
    20761 aagaaaagca aatatcaata atagcatctg gggacccatt aatatatggg ataggtagat
    20821 atctatctaa aaatattgat aataagatgt taaacgtggt ttctgggatt agttcattac
    20881 agtacatatt ttcaaaaata tatgtagata tgaatgatgt atatattaca agtagtcatg
    20941 gcaaagtacc agattttgat tacatattat cacataaaaa agtatgtatg gttacagatt
    21001 caaagatagg accaaaacaa ataagtagag aaataataga tagaaatcta aataaaatta
    21061 ttgttgtagg agaaaatctg tcatatgaca atgaaaaaat aacaatagca aaaccagaag
    21121 agataataag aatggacaat tttgatatga atgttgtggt gattttagat gaggaatagt
    21181 gaatttataa caggtaaagt tccaattact aaggaagagg ttagagcaat atcaataagt
    21241 aagttaaatt tagtaaatgc taaaaacctc atagacatag gggctggtac aggaagtgta
    21301 agtgttgaag ctgcatataa ttatcctaat ttaaaggtta tatctataga gaaaaatgat
    21361 gatgctatag agcttataga gaaaaataaa aaaaaattca acttaaaaaa tatagaagtg
    21421 ataaaaggat atgctccaat taatctaggg ttaaatgtta aagttgagtc tatttttctt
    21481 gggggaacag gaaataatct ggaagaaata atagaatggt ctaaaaaaaa tcttgttaca
    21541 ggaggaagac ttgtagctaa ttttataata atagatacat ttaatcaaac tttaaaactg
    21601 cttaaaaagc atggatttaa agaaatagat gtatgtgttt tgaatgtttc taaactggag
    21661 aaactaggaa aaggtgaata ttttaaacca ctaaatccta tatatataat atcttgtgaa
    21721 aaaggggaaa atgatgatga ataaagtaca ttttgtagga gcaggacctg gagataaaga
    21781 gctgataaca ttaaaaggat acaaattatt aagtaatgca gatgtagtga tatatgcagg
    21841 ttcacttgtt aatcctgaac ttttggaata ctgtaaagaa gattgccaaa tacataatag
    21901 tgcacatatg gatttacaag agataataga tgttatgaga gaaggtatag aaaataataa
    21961 atctgttgta agactgcaaa caggtgattt ttctatatat ggttcaatta gagaacaagt
    22021 ggaagattta aataaattga atatagatta tgactgtact ccaggagtaa gttctttttt
    22081 aggggcagca tcatctttag gggttgaata tacagttcca gaaatttctc aaagtgtaat
    22141 tataacaaga atggaaggca gaactccggt tccagagaaa gaatcaatac aatcatatgc
    22201 taagcatcag acatctatgg taatattttt atctgttcaa gaaattgaga aagttgtgtc
    22261 taaattactg gaaggtggat atccaaaaga tactcctata gcagttatat acaaagcaac
    22321 ttgggcagat gaaaaaatag ttaaaggaac tttaagtgat atagctgtaa aagttaaaga
    22381 aaacaacata aataagactg ctttaataat ggttgggaga tttttaggag aagagtataa
    22441 taattcaaag ttatatgata aggatttcaa acatgaatat agagggtaat attgctataa
    22501 tctgtattac agaaaatgga aaaaaattag ctttaaagat aaattctcta gtaaataact
    22561 gtgttatata tcaagtaaaa aataaaaaaa gtaatttagt tgttgaagaa acatgtgtgc
    22621 atacagttca aaagaagtta agtgattttg taggagaaat atttagcaaa tttgattaca
    22681 tagtatttat aatggctaca ggtatagttg tacgaagtat agcaccatac ataataagta
    22741 agtttagtga ccctgcaatt ttggtaatgg atgaaaaagg caaaaacgta ataagtttat
    22801 tgagtggtca tattggaggg gcaaacagct tgacacagta cataagtagt cttattgatg
    22861 ctaatccagt aataacaaca gctactgaca taaatcaaaa agcttcctta gatatgatag
    22921 caaaaaaact aaatgcacat attgataatt ttagagaaag tgtaaaagaa gtaaattcta
    22981 tgctagtgaa taataaatgt gttggattat atgttgatga aggatatcaa gttgatacta
    23041 ggggatttaa acttatagaa agtaaggatg agttaagaga tagtttttca aacgcatata
    23101 tagaaaaatt agttgtagta agcaataaaa taaattgtat tgaagatatt gagaatttaa
    23161 acctagataa taaatttgaa cattgctata gtacccaaaa aataataaag gtaattccaa
    23221 gagatatagt gataggaatt ggctgtagaa gaaacacaga tagtgaactg atgtataatt
    23281 cacttgaaga gtttcttaat aaacaaaata tagatattag agcaataaac acagttggaa
    23341 gtatagaact gaaaaaagac gaaaaagcaa taattgaatt atcaaaaata ttgaaggtgc
    23401 catttaaaac attttcagta gatgaaatat ctaaggttga taatcttttt gataaatctg
    23461 attttgttaa aaaaaatgtg ggtgtgtatt cagtagcaga acctgtagca tatcttttga
    23521 gcaaaggtaa tttgttagtt gaaaaacata aatataaagg aataactttt tcagtgggga
    23581 gaataaaaat atgatatacg ttgtaggaat tggaccagga agtaaagata caatgacttt
    23641 agaagcaata aaagcaatag aagattctga ggctattgtt ggatataaga cttatataaa
    23701 actaatagaa gaatttatac aagataaaga aataatccaa aatggtatga ggcaagaagt
    23761 tgatagatgt aaacaagcag tagaggaagc aaaaaaagga aaaaaagtag cagttgtaag
    23821 tagtggtgat gctggaatat atgggatggc aggtcttatt ttagaattaa tatctaaaga
    23881 agatgaagat ataaaagtaa aggtaattcc aggtgttact gcaagtattg gtgcagcagc
    23941 tatacttgga gctcctatta tgcatgattt ctgtcatata agtttgagtg atttaatgac
    24001 tccgtgggaa gtaattgaaa aaagattgag attggctgct gaagccgatt ttgtaatttg
    24061 tttgtataat ccaagaagta agggaagaag tgaacatcta agcaaagcat ttaaaataat
    24121 gggtgagttt aaaggtggag atacacctgt tggagtggta aaagatgtag gtagagaaaa
    24181 agaagaaaag tttgtatgta cttttgaaaa tatggacttt gaaaaagtcg atatgactac
    24241 aatggttata ataggaaata agtctaccta tattaatggt gaattgatga taactccaag
    24301 aggttataca gtatgatttt gattttagga ggaacttcag atagtttatc tatatgtgat
    24361 aagataaatg aactgaaaaa tcaaccatat atcctttcag ttactacaga ttatggaagg
    24421 gaacttgcac aacaacatgc agagaatgta attttaggta agcttggaaa agaagatatg
    24481 ctaaaattta taaaagataa taatatagta aaaataatag atgccactca tccttatgca
    24541 gttgaagtat ccaaaactgc tattacttgt gcaaaattat tgaatataga ttatataagg
    24601 tttgagagaa aatctttaat tgaagaaata gattatgata ataaatttat agtagataca
    24661 attgaagaag cctgtgaaat agcaaataaa atagggacaa atatattcat aggaacagga
    24721 agtaaaaatt tgaacagatt tatagaggaa ataagtgata aaaatttagt tgttagagtt
    24781 cttccaacga gtgaagtcat attaagttgt gaaaaattag gtttaagtgc agataatata
    24841 gtagctatga aaggtccatt tagccagtat ataaatgaag aaacatataa acattacaat
    24901 atagatttag tcataacaaa agaaagtgga atagctggtg ggttcttaga gaaggtaaat
    24961 gcatgtaaaa ctttcaatat accagtaata attataaaaa gagaatcgat taactacgaa
    25021 aatgtattta atgacataaa taaaattaaa gacatacttg tgtaattttt aggaggagaa
    25081 tatatgaaga aagccttatt agtagtgagt tttggtacaa gctatcatga aacgagagaa
    25141 aagacaatag atatatgtga agataaaata aaaaattcgt taaaaagcca tgattttttt
    25201 agagcttata catcaaatat gataataaat aaaataaaaa aaagggatgg aatagaaata
    25261 gataatccaa tacaggcttt agataaaata tatgaacaag gatatgatga agtaataatc
    25321 caaacacttc atattatatg tggcgaagaa tttaacaaat taaaagaaca agtagatgga
    25381 tattcttcta aattcaaaaa gattgtatta ggaagacctt tgcttacaca tattgaagat
    25441 tatcaggaag ctgtagaggc aattaagcat caaattcctc atatggaaag taatgaagca
    25501 gtagtattta tgggacatgg aacacttcat gaatcacatt cagcgtatcc agcattggaa
    25561 tacatgctta gggataatgg aataaatgct tatgttggta cagttgaagg gtatccagaa
    25621 atagaacatg taataagaag attaaaagaa ggaaatataa aaactgtaaa tttgatgcca
    25681 tttatgttag ttgcaggaga ccatgctata aatgatatgg caggagatga agaagattct
    25741 tggaaaacaa tattagaaga aaatggattt aacgtaagag ttcatttaaa aggactagga
    25801 gaaaattctt atatacaaga taaatttgtt cgtcatgctg taaaatgtgc agagaatgcg
    25861 aagttctatg gtataggagc agggccagga gatggttctt tacttacgat aaaagcggtt
    25921 aatactttaa agaaactgga tattctatac actccagaat caaaaaaggg tggagatagt
    25981 ctagctttat caatagttag tgaatattta cctgaatcag tggaaataaa gtctaggcat
    26041 ttcccaatga gttttgatgg gaatgaaaaa agtttagctt gggacaatgt ggcacaagaa
    26101 attatatcag atgttaatga tggtaaaaat gtaggatttg ttacattagg agaccctatg
    26161 atttatagta catatgtata tataatgaaa agaatattag gagaggtaga agtcgaaact
    26221 ataccaggaa tttcatcatt ttccaatata gcatctaatc agaattttcc attagtcatg
    26281 gataaagaag ctttagtggt aattccttgt actatggaag atgataagat agagtatgct
    26341 ttgcaaaatt ataattcaat agtattgatg aaagtatata aaaattttaa agaaataata
    26401 aaaaaattag aaaagtatga tttaatagaa catgctattt tagtaagtaa ttcttcccaa
    26461 gaaagcgaaa atgtgtttac agatttaaaa gaagcgcacc ttgaagataa gatatcttat
    26521 ttttctacta tactagtaaa taaagataat aaaataaaat aggtgaaagt aatatttaaa
    26581 ggagacttaa tatgaatata gtggttggaa ctaggggtag taatctagcg cttatacaaa
    26641 cagaatgggt aataaatgaa ttaaaaaaga agtatccaga aattagtttt gagattaaaa
    26701 tcataaagac aaaaggagat ttaattcaaa atgtttcact ggataaaata ggtgataaag
    26761 gattgtttgt caaagaaata gagcaacaat tattagatgg aaaaatagac atagcagtac
    26821 atagtatgaa agatatgcct tcttatttag cagatggact aaaatttgct catacgccta
    26881 agagagaaga cccaagagat gttctaatac ttagagaagg atataaaaat ttagatgatt
    26941 tacctcatgg agcagtaata ggaacaggaa gtaaaagaag gaagtttcaa ttattgaaac
    27001 aaagacctga tttaaatata gtacaagtta gaggtaatgt ggaaactagg atacgaaaaa
    27061 taaaagatga aaatatgcat ggtattgtgt tggcagcatc aggaataatt agagctaatt
    27121 tgcaagataa aataagttct tatttacctg ttgatgttgt tattccagca cctgcccaag
    27181 gagctttagc tatagaaatt agaagcaatg atagtacgat agagggaata gtaaattcac
    27241 tgaaggatga gaatacagaa atccaaatat tggctgaaag aggtttttta gatggtgtaa
    27301 atggaagttg tcatattcca atggcagctt attgtgaaat aatccaagat aaaatacatc
    27361 ttactggctt atatggagat tcagaaggaa aaaaagtagt aatcaagtct atagatggag
    27421 atatttcttc tcctagagag ttaggtttaa agttagctaa acttgtattg aaggagtatg
    27481 agaattatga agggtaaggt ttacttagta ggggcaggac caggtgatta taaactcatg
    27541 actttaaaag gtttagagtg tataagaaaa tcggatgtaa tagtatatga tagattagca
    27601 aatagtagtt atttaagaga agctaagcct gattgtgaac ttatatatgt aggcaaggca
    27661 tcaagtaatc atattttgcc acaagaagat ataaatagaa ttatagcaga aaaagctaaa
    27721 gaaggaaaaa ttgtaactcg tcttaaagga ggagaccctt atgtatttgg tagaggggga
    27781 gaagaagcag agactttagt agatgaaggt atagaatttg aagtagttcc aggtataact
    27841 tctgctatag gaggtttatg ttatgcgggt attcctataa cacatagaga ccatgcttcg
    27901 tcatttcatg taataacagg tcatttgaag ggtgatgata gtggagaatt aaactggaat
    27961 gctcttgcaa ataacaaagg tactcttgtg tttttgatgg gaatttcaaa cctagagaaa
    28021 ataagtgaaa acttaatgaa agaaggaaaa gataaggata cacctgttgc tcttataagt
    28081 tgggcaacta gatataatca aagagttgtt acatctacac ttgaaaatgt ttatgaaact
    28141 gctattaaag aagaagtaaa accgccaact cttatagtag ttgggagtgt tgtaggactt
    28201 agagaaaagt tgaacttctt tgaaagtaag cctttatttg gaaaaagtat tgctgtaact
    28261 aggtctagaa atcaaaatag tgtattggta gaaaaaataa tggatttagg tggaaatcct
    28321 atagaaatac ctactattaa ggtagaaaaa atacaaaata atattaactt agaaaatgaa
    28381 ataaaaaata taaataagta taattatcta atactaacta gtaaaaatgc cgtagaaatc
    28441 ttctttgaaa agatatatga aatgaatttt gatttaagga tattatctaa tttaaaggta
    28501 tgtgctatag gttctgccac atcaaatgag ttgaaaaaaa gaggaattat agcggatata
    28561 gtaccaaaaa aatttgtagc agagtcactg tatgaagagt tagcgcctat tttaaatgat
    28621 gacgataata tacttatacc tagagcagaa aatgctagag attatctggt tgacaaactt
    28681 aaggctattt gtgaagtaac agaagtacat atatatagaa cagtaataga tgaggagaaa
    28741 aaaggtgaga tattagatat tttaaattct aatgacatag attatataac atttactagt
    28801 tcctcaacag taaataatct tgttgaaatt ataggaaaag aaaatattaa aatattagaa
    28861 aaaataaaaa cactatctat aggtcctata actacagaga caataaatag tttgggaata
    28921 aaattgtaca aagaatctgc tacatctact atagattcgt tagtagattt aattataaaa
    28981 aattaatttt ggaggcttga atatgttaag aagaccaaga agactaagag caagtaaagc
    29041 aatcagaaat ttggtaagag aaactaaggt gaatgtagaa gacttaatat atccactgtt
    29101 tgtagtagag ggggaaaata taaaagaaga aattaaatct ttaccagatg tctatcattt
    29161 atcaatagat atgctagaag acgaaataaa agaaataagt gagttgggaa ttgaacatat
    29221 aatgttattt ggtgttccag atgaaaaaga tgagtgtgct tcacaagctt ttaatgataa
    29281 tggaatagtt caaaaggcaa ttagaaaggt aaaagaaata aattcagata taaatgtaat
    29341 aacagatgtc tgtatgtgcc aatatacaag tcatggacat tgtgggattt taactgatac
    29401 tggttatgtt gataatgata aatcattgga gtatttggct aaaatatctg taagccatgc
    29461 taaagcagga gctgatatgg ttgctccatc tgatatgatg gatggaagaa tacaagcaat
    29521 aagagaagct ttagatgaaa atggattaga aaatgttgga atcatggctt atagtgttaa
    29581 gtatgcttca aattattatg gaccttttag agaggcagct cattcagcac catcttttgg
    29641 agatagaaaa acatatcaaa tggacccagc aaatagcaat gaagctataa tagagactga
    29701 acttgatata ttggaaggtg cagatatact tatggttaaa cctgcattat catatttaga
    29761 tattataaga agagttaaag ataattttga cttacctcta gcagcttata atgtaagtgg
    29821 agaatactct atgcttaagt ttgctgtgaa ggaaggttta ttaaatgaag atgtaattct
    29881 tgaatcaatt acatctataa aaagagcagg agcagatata ataataactt attttgctaa
    29941 agacattgct aaactgttga aaaaataaat tctagtagta taaagaatat caaaaagtat
    30001 aggaattgta attaactatt atacagtagt tttgtttaga catttattga agaataatag
    30061 aaactaattt gcaatttcta tactttattt atgtaactaa ataaaatttg gaggtggaag
    30121 atgctatatc ctattaattt aaaattagat gagttagatg tagttataat tggtggtgga
    30181 gaagttgcat ataggaaatg taaaaatttt ttagagttta acaaaaatgt tactatagtt
    30241 tctaaacaaa ttttaaataa attttatgat ttaaaaggaa atataaaaat aataaaagat
    30301 gattataaag aaatatatat aaaagatgct tctgtaataa ttgctgccac aaataataga
    30361 gagttaaata tggaaatagg attatattgt agagcaaaaa ataagctagt gaatgtagtt
    30421 gataatatag aaatatcgaa ctttacggtt ccatcatata taaaaagagg agatttactt
    30481 ataagtgtgt ctactggggg caagagtcct tcattatcat caaagataaa aaaagaaatt
    30541 gaagagagat atactgaaga ttatgaggag tatttaaatg tattaggaga tataagaaaa
    30601 aaggttataa aaaaatacga agataaaagt aaaagaaaag atgtgcttaa tatgttggta
    30661 acacttgacc tagaagaact taagaagttt gatatataaa aaataaaata aaaaatgtta
    30721 aaaaggtgtt gacggattat ttttaag
//
LOCUS       DAEORM030000044        29406 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.044, whole genome shotgun sequence.
ACCESSION   DAEORM030000044 DAEORM030000000
VERSION     DAEORM030000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 29406)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29406)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 29406)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29406
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.044"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            174..3227
                     /locus_tag="KRH23_002640"
     CDS             174..3227
                     /locus_tag="KRH23_002640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SrtB-anchored collagen-binding adhesin"
                     /protein_id="HHS5225918.1"
                     /translation="MKNILKRVCTGFLALATVITTLPATTAHAAEKQYWTESDERVGI
                     VEQVMNDGSIKATFNEGYMKVEGETAYCIDINTAFQNGYKTRADASTRMSANQISDVA
                     LSIEYVKQYAEKHKELNYKQVYLLEQVVVWQRLSVHLGWQCDNVRAAYSEISKATQEE
                     VFAGAKAFVKENKGRYECGGYIYSGEGQELGQFWAKLNVGNAKLQKVSSNAGITDGNA
                     NYSLTGATYGVFADKECQKQLATLTTDENGNTDVVEVKAGTVYIKELSAPLGFQVDTT
                     VYSLNVEVGKTATLKVSDTPKVTDTLIELFKIDMETQKNNPQGTASLAGAEFRWNYYD
                     GFYTKDNLPSKPTRTWTTKTVEEKDKQGNVHYITKLADTYKVSGDAFYMQNGKAVLPL
                     GTLTVEEVKSPSGYLLEGAYMQANGSSEQIKGVYLTQIAEDGDLAVLTGANQFSVSDK
                     VIRGGVKIQKRDLETGDTKPQGSATLKDTAFDIISLNENEVLVEGKLHKKNEVVKTIH
                     TDISGVAMTSDNLLPYGKYKISEQKAPEGYLTDGAKEIEFEITENGKIVDLTDKDHSI
                     YNQIKRGDIEGVKIGAGTHKRLADVPFKITSKTTGESHIVVTDDNGQFSTSSDWASHK
                     HNTNKGQSSEDGVWFGTSEPDDSKGALPYDTYIIEELRCTSNQGFKLIPPFEIVVSRN
                     NHVVDLGTLTDEYEKEITIHTTATGKDGEKTILAGKEVTIVDTVKLDGLVKGTKYQLK
                     GWQMVKEENAELIIDGKRVENDYTFVADDEEMKVEIAYTFNASALGGKNLVTFEELYD
                     LSNPDEPVKVAEHKDIEDDGQTVLITERIIRIHTTAADLDGDKEIQADKEITIIDTVT
                     LEGLEVGTKYQLKGWQMVKEENAELLIDGKRVENDYTFIADKENMTVEIAFTFDASTL
                     GGKQLVTFEELYDLSNPDEPKKVAEHKDIEDDGQTVTIKEIPEEPEVPEKPEEPTTPE
                     KPSQPTDSPKTGDNTNVMAFVVLLLASAGMLSGTYLWKKYRKKED"
     gene            3231..4304
                     /locus_tag="KRH23_002641"
     CDS             3231..4304
                     /locus_tag="KRH23_002641"
                     /EC_number="2.1.1.37"
                     /inference="COORDINATES: protein motif:HMM:NF012372.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003886 - DNA
                     (cytosine-5-)-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HHS5225919.1"
                     /translation="MAITLGSLFDGIGVFPLAASNYGIVPLWASEIEKVPISITKKHF
                     PQMQHLGDITKLDGAKIPPVHIITFGSPCQNLSTIGAREGLAGAKSGLFHHAIRIIQE
                     MRCATDGKYPVIAVWENVRGAFSSNNRLDFRAVLESFADTEIPMPASRRWANAGMVRG
                     GKVDVCWRLLDAQYWGEPTLSQRRKRIFVVADFRGQRAAEILFKPHKLHAHIDPSRKS
                     WLSSGERNRISVNQARGKIPVLCPFEERRTRGSAKYQDTQGFVRSFGRPNDPFPTLLA
                     GGPGVFSFWYEGEEKEGFIRYLTPIESERLMGLPDDWTKYGNTGTINSDYARWRALGN
                     AIAVPCAEHIMAGIAEVLKESED"
     gene            4505..4828
                     /locus_tag="KRH23_002642"
     CDS             4505..4828
                     /locus_tag="KRH23_002642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014080830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HHS5225920.1"
                     /translation="MELKFVVPNMAQTFGNLEFAGENEVRQQRVNDRMTVVSRSYNLY
                     SDVQRADDIVVTLPAKAGEKNFQPEQKVKLINPRITADGYNINGRGFTNYILLADDML
                     PVESK"
     gene            4845..5213
                     /locus_tag="KRH23_002643"
     CDS             4845..5213
                     /locus_tag="KRH23_002643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009588269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HHS5225921.1"
                     /translation="MRLANGIIIDKEKTFGQLKFSALRREVHVQNEDGTISEEIKERT
                     YDLKCREQGRMIQVSVPANIPLRDFEYNAEVELINPVADTVANATYRGADIDWYIKCD
                     DLVLKNKGQTPNNPNAAPKK"
     gene            5231..6628
                     /locus_tag="KRH23_002644"
     CDS             5231..6628
                     /locus_tag="KRH23_002644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase HerA domain-containing protein"
                     /protein_id="HHS5225922.1"
                     /translation="MALFKYKGNRIRASDQHLVYRFCMGTLILLFLCIVVLLNLKQIV
                     HTDWGNFNLTEMEFPLSSYNFITLLIAAGVCALVAFLYYRFCYDSFKKMVHRQKLARM
                     ILENKWYEAEQAKQSGFFTDLPSSTKETITWFPKIYYQMKNGLLHIQCEISMGKYQEQ
                     LLNLEDKLESGLYCEMTDKVLHDGYIEYTLLYDMVANRISIEEVKAEHGGLKLMKNLI
                     WEYDALPHALIAGGTGGGKTYFLLTIIETLLQTNAVLFILDPKNADLADLGTAMPNVY
                     HTKEEMINCVNSFYDGMVSRSEEMKQHPNYKTGENYAYLGLAPHFLIFDEYVAFFEML
                     GAKESMNLLSQLKKIVMLGRQAGYFLIVACQRPDAKYFTDGIRDNFNFRVGLGRMSEL
                     GYGMLFGSDVKKKFFQKRIKGRGYCDVGTSVISEFYTPLVPKGHDFLKEIGRLASKRQ
                     VLFEEQGKDNDNVVE"
     gene            6896..8122
                     /gene="mobT"
                     /locus_tag="KRH23_002645"
     CDS             6896..8122
                     /gene="mobT"
                     /locus_tag="KRH23_002645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MobT family relaxase"
                     /protein_id="HHS5225923.1"
                     /translation="MNDKEWLEAFKEKRALYGVTQLRLAVMAGISREHLSRIESGKVS
                     LTLEMKEKLLTALEKFNPDEPLFLLFDYVRIRFPTMDIKHIIKDVLRLNIQYMLHEDW
                     AYFSYTEQYYIGDVFVYTSADEEKGVLLELKGKGCRQMESYLLAQERSWYDFLMDCLV
                     EGGIMKRLDLAINDRTGILDIPELIEKCKNDECVSVFRHFRFYASGEISHQRERNHKE
                     MGTTMYIGSMKSEVYFCIYEKNYEQYIKAGVPLEEAPVKNRFEIRLKNERAYYAVRDL
                     LTYYDAERTAFSIINRYVRFVDKEENKPVSEWKLNEKWAWFIGEGRPPLKLTTKPEPY
                     TLGRTLRWISRQVDPTLLMLEEIAKKTGVNYLKEIRQYTKLTEKHEQIIRQQTTTIEE
                     IVLSDEERNEKDVGIF"
     gene            8106..8249
                     /locus_tag="KRH23_002646"
     CDS             8106..8249
                     /locus_tag="KRH23_002646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HHS5225924.1"
                     /translation="MWVFFKDLLLVSVGMGIGVVLMCILQVGKDADNVMNELKENKES
                     EEQ"
     gene            8250..8471
                     /locus_tag="KRH23_002647"
     CDS             8250..8471
                     /locus_tag="KRH23_002647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002570387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5225925.1"
                     /translation="MNFGQNLYQWFLSNAQSLVLMAIVVIGIYLGFKREFSKLIGFLI
                     VALIAVGLVFNAGGVKDVLLELFNKIIGA"
     gene            8494..9306
                     /locus_tag="KRH23_002648"
     CDS             8494..9306
                     /locus_tag="KRH23_002648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896901.1"
                     /note="N-terminal region resembles flavodoxins. C-terminal
                     ferrodoxin region binds two 4Fe-4S clusters; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EFR1 family ferrodoxin"
                     /protein_id="HHS5225926.1"
                     /translation="MNGIIWICQNKTLGSEKMIGIYLSGTGNTKHCIEKLVGLIDNSA
                     KVFPLEMPNLIEEIKKSDTIILGYPTQYSNAPYMVRDFIKQNSSLWKDKKIFCVATMG
                     AFSGDGAGCTARLLKKYGASILGGLHIKMPDSVCDSKLLKKTLEENREIVKQADKKIE
                     LVAEKIKQGQYTKDGISFFSHLIGLFGQRLWFYNKTTGYTDKLKINQDCIGCNLCVSL
                     CPMKNISIQNGKAVAGNQCTMCYRCISHCPKKAITLLGNQVTEQCQYEKYCE"
     gene            9405..9626
                     /locus_tag="KRH23_002649"
     CDS             9405..9626
                     /locus_tag="KRH23_002649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5225927.1"
                     /translation="MSDIFKDMQMKTGCEYISDLPSHKRIVWKELKKQNLSQYDKKQL
                     EDFSNYVFGLSYDTLQAVIKQQKGREKRV"
     gene            9623..10108
                     /locus_tag="KRH23_002650"
     CDS             9623..10108
                     /locus_tag="KRH23_002650"
                     /inference="COORDINATES: protein motif:HMM:NF018926.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HHS5225928.1"
                     /translation="MKELRVCMESALPDEEVKKAWFTLPIDEEDVLEKLGVDVESDDY
                     RIIETDVPFKTDIKENTSVWRLNDLFYTFLTLPHFMQLDCELLLERLPSLDLLHAYHD
                     AIHFYEGAVSMIEVARRKMIEYNSVSEEAIHYMDLEKFAGYLEENGRFLKTEHGIYQL
                     P"
     gene            10125..10628
                     /locus_tag="KRH23_002651"
     CDS             10125..10628
                     /locus_tag="KRH23_002651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004843360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HHS5225929.1"
                     /translation="MTDDMQVYIANLGKYNEGYLVGAWFSFPIDEEDVKEKIGLNENY
                     EEYAIYDTDNFPMEIGEYVSIEELNRMYEMMEDLPEYVVECLDEFVGHYGSLEEVAEH
                     KDEVYFYPDCETMTDVAYYYIDELQTLGEIPSQLQDYIDYEAYGRMLDMVGTFISTSR
                     GMCEIPY"
     gene            10714..11103
                     /locus_tag="KRH23_002652"
     CDS             10714..11103
                     /locus_tag="KRH23_002652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006354961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HHS5225930.1"
                     /translation="MKKIKSYTGIWNVEKVLYAINDFNLPFPVTFTQITWFVITEFIV
                     IVFADIPPLSMIEGAFLKYFGIPVALTWFMSQKTFDGKKPYSFLKSQLCFYFRPKVTY
                     AGKAVKLRTEKFHETITAVRSVKYVPD"
     gene            11090..13540
                     /locus_tag="KRH23_002653"
     CDS             11090..13540
                     /locus_tag="KRH23_002653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HHS5225931.1"
                     /translation="MFPIKYMDNNLVWNKDNEVFAYYELIPYNYSFLSAEEKFIVHDN
                     FRQLIAQSREGKIHALQIATESSIKNIQEQSKKLVSGKLRDVAIQKIDEQTDALVSMI
                     GDTQVDYRFFLGFKLMVPDETLNLKNIKKSAWLTFQEFLHEVNHTLMNDFVSMPNDEI
                     NRYMKMEKLLENKISRRFKVRRLEVSDFGYLLEHLYGRDGIVYEEYDYPLPKKKLKKE
                     TLIKTYDLIRPTRCLIEENQRYLRLEHEDSETYVTYFTVNAIVGELDFPSSEIFYYQQ
                     QQFTFPVDTSMTVEIVENRKALSTVRNKKKELKDLDNHAFQSGSETSSNVVDALDSVD
                     ELETDLDQTKESMYKLSYVVRVCADDLDELKRRADEVKDFYDDLSVKLVRPAGDMLGL
                     HSEFLPASKRYINDYVQYVKSDFLAGLGFGATQQLGENTGIYIGYSVDTGRNVYLQPS
                     LASQGVKGTVTNALASAFIGSLGGGKSFCNNLLVYYSVLFGGQAVILDPKSERGNWKQ
                     TLPEIAHEINIVNLTSDKENAGLLDPFVIMKDVEDGATLAKEILTFLTGISTRDGEKF
                     PVLIRAIGKVKDSKQRGLLNVIKELRKEETVIANNIADHIESFVDYDFAQLLFSDGSV
                     ENAISLDNQLNIIQVADLVLPDKDTSFEEYTTIELLSVAMLIVISTFALDFIHSDRSI
                     FKIVDLDEAWAFLNVAQGETLSNKLVRAGRAMQSGVYFVTQSAYDVSKESLKNNIGLK
                     FAFRSTDINEIKQTLEFFGIDKEDENNQKRLRDLENGQCLLQDLYGRVGVVQIHPVFE
                     ELLHAFDTRPPVSRDEVV"
     gene            13540..15705
                     /locus_tag="KRH23_002654"
     CDS             13540..15705
                     /locus_tag="KRH23_002654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006354959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CD3337/EF1877 family mobilome membrane protein"
                     /protein_id="HHS5225932.1"
                     /translation="MNERWKVSKITKKNIKSIKRYMTKQKVLRFIKMTLLVIGITLIL
                     LSLLGTVAQAAGLVDDTVSAENLYSKYPLQNYTLDFYVDNSWGWLPWNWLDGIGKSVQ
                     YGLYCITNFIWTISLYLSNATGYVVQEAYKLDFINDMADSIGKSIQTLAGVTQNGFSS
                     TGFYVGFLLLIILIVGIYVAYTGLIKRETSKAFHAVINFVVVFLLSASFIAYAPDYIK
                     KVNEFSSDVSTAALDLGTKIMLPNSDSEGKDSVDLIRDSLFSIQVEQPWLLLQFGNSN
                     KEEIGAERVESLVSVSPDEEDGKTREEVVKTEIEDNDNTNLTIPQVINRLGMVFFLLF
                     FNLGITIFVFLLTGIMIFSQILFIIFAMFLPISFLLSMIPGYESMTKQAIVRVFNTIM
                     TRAGITLIVTVAFSISSMFYNISTDYPFFMIAFLQIVCFAGIYMKLGDLMNMFSLNAN
                     DSQGVARRIFHRPYMFMRHRARRMERRMTRAASLGVAAGTGAMAGSMAGKQQTQANEQ
                     RSRNNVSKGSFKDVPQKAGAMVGAVMDTKNKMKEKAGAVRENIKDMPLQASYAVHSVG
                     RQAKESVSDFKRGIVQEREHRQSGREEKRQQHRQNIADKRMALQKMQEQSGIHKKHER
                     PVAVFKENALENRSKVQEVKRPVTSEKSNAPVIKRQQKMNVEQIEKVRPLSSYEKNHQ
                     NDGANRHSIKSQSVQTVQKSQVHKDTNRKVVSKKGQKKK"
     gene            15702..16712
                     /locus_tag="KRH23_002655"
     CDS             15702..16712
                     /locus_tag="KRH23_002655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003455364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
                     /protein_id="HHS5225933.1"
                     /translation="MRLKQVLLLGSLFPFLLAVTLFFGVLVSADNDDSGGDYSSGVTG
                     MNLSAEVLKHQPMVEKYAKEYGISEYVNILLAIIQVESGGTAEDVMQSSESLGLPPNS
                     LDTESSIKQGCKYFASLLSSCKEQGITDINVAIQSYNFGGGYVGYVAGNGKKHTYNLA
                     ENFAKDKSGGKKVTYTNLIAVKKNGGWRYSYGNQFYVELVNQYLYVTQFDDETVQAIM
                     NEALKYNGWEYVFGGSSSTTSFDCSGLTQWCFGKAGISLPRTAQAQYDATQHIPIAQA
                     KPGDLVFFHSTYNAGSYVTHVGIFVSPTQMYHAGSSGIGYTDLTSSYWQQHLIGAGRV
                     KQ"
     gene            16730..17641
                     /locus_tag="KRH23_002656"
     CDS             16730..17641
                     /locus_tag="KRH23_002656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HHS5225934.1"
                     /translation="MKWKKKKQTENKQEMKEKKKPTLKVGTHKKSVIALWAVLIVSVS
                     FGVYKNFTAIDMHTVHEKETVQLRLNDTNGIENFVKNFCKAYYTWDNSKETLEKRTSS
                     INGYLTEELQVLNADTIRTDIPTSSTVSDVLIWNVEQSGNDEYEVLYEVVQSIKEGDQ
                     TRSVRSSYMVTVHVDTKGNMIIVQNPTLAPMMETSDYEPKTVENDSQVDADTVSDATA
                     FLETFFKLYPTATDKELAYYVEENVMEPVQREYQFAEVLNPVFTKDGDNIKVNVSVKY
                     LDNLTKAEQISQYELILHKDSNWKIVG"
     gene            17782..18408
                     /locus_tag="KRH23_002657"
     CDS             17782..18408
                     /locus_tag="KRH23_002657"
                     /inference="COORDINATES: protein motif:HMM:NF012655.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HHS5225935.1"
                     /translation="MNGYEKFLELPNEKQLRIINAGFEYFGKYGYKGANTEDIASRAE
                     ISKGLLFYYFKNKESYYLFLCEFCQNLMLKSFQETNFQEITDFFELIDFATKAKLKII
                     AEYPFITDFSVNLIADKSIKQGSKSEEYVNNAIYNSFDIYFKNIDFTPFKEEIDVKKI
                     YQMMLWLSEGYINEKKRMNMPVILEDFLVEFASWKALFKKMCYKEEYL"
     gene            18405..19292
                     /locus_tag="KRH23_002658"
     CDS             18405..19292
                     /locus_tag="KRH23_002658"
                     /inference="COORDINATES: protein motif:HMM:NF012235.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHS5225936.1"
                     /translation="MNVIEINNLTKDFGNNKGIFDLSFSLKQGEIVGFLGSNGAGKTT
                     TIRHLMGFIKANTGSAKIANMDCFHNAHLVQEKIGYLPGEIAFMDNMTGEEFIQFMAD
                     MKSITDLQYAKELIVYFDIDTKIKIKKMSKGMKQKIGLIIAFMQDPPILILDEPTTGL
                     DPLMQTKFVDLIKKEKAKGKTILMSSHIFEEIENTCERIVMIKDGRLVADENINTMRN
                     KMNKHYEISFSNMEDAIHFQELYSTNSYRKNNVVYLLSNQNINHLIRELGKFNIEDIN
                     ARHQTLEEVFMKYYGGSVK"
     gene            19289..20086
                     /locus_tag="KRH23_002659"
     CDS             19289..20086
                     /locus_tag="KRH23_002659"
                     /inference="COORDINATES: protein motif:HMM:NF024091.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HHS5225937.1"
                     /translation="MSIPLLKIELKSNSKIILLFLAIITLYAGIITAMYNPELGAGIN
                     ELAKSMPQFFAVFGMENPGTTLLDFLNNYLYGFILILIPFIYIILMCYKLVAKHIDKG
                     SMAYLLNTHYSRIQIILTQFIVLVIGLLVLVCYATGLIIFISNLMFKGEMEIIKFLLV
                     NLGLFILEVFLSTLCFMFACLFNELKFSIGLGAGLGMIFFLVQMLSQVSDDIEFLKYF
                     TPLTLFSPENIIKYDIESFMYLGVLLISAVVFFVITMKKFKKRDLSL"
     gene            20266..20952
                     /locus_tag="KRH23_002660"
     CDS             20266..20952
                     /locus_tag="KRH23_002660"
                     /EC_number="7.6.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014262100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHS5225938.1"
                     /translation="MAILETKDLKKIYGSGENEVHALDGVSISVEEGEFVAIVGTSGS
                     GKSTLLNMLGGLDRPTSGSVVVRGKELMQMKDEQLTIFRRRNVGFVFQNYNLLPILNV
                     YENIVYPIEIDGSKVDKEFVRQIIHNLGLERKLKNMPNNLSGGQQQRVAIARALATKP
                     AIILADEPTGNLDSKTSMDVILLMQSISREFNQTILMITHNEEIAQMADRIIRIEDGK
                     VVSGGVGYAR"
     gene            20942..23500
                     /locus_tag="KRH23_002661"
     CDS             20942..23500
                     /locus_tag="KRH23_002661"
                     /inference="COORDINATES: protein motif:HMM:NF014717.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHS5225939.1"
                     /translation="MHDNRNKEVIKRVEKGMMKANRTRNIFAVVAVALTTFMITTIFS
                     LGINYKENMELMEVRTSGTNANVSLTMPTNEQEKEIRDLDYVDTVGTQYMIGSVAGKN
                     EADRDLAIAMQYYDNTEWEKHYKEAISNINGKYPKKENEIMLSEDALSQLGIKEPKLD
                     MEIPLSYVSKDGEQKDTFTLSGWFHSYTGTGMAFLSESYCQEHGYTMQNSGVLSISLD
                     NPKDNFYDIQDDITLNENQTFQGSVSMSSSNGSVYAMIILLVFFIIGSGYLLIYNVLY
                     ISISRDTRFYGLIKTLGTTEKQIKTLVKRQALTFGCIGIPIGVILAGVLSFGIVPVIL
                     ENAFDSGKSIMDAEMFFHPSIFILSIIFSALTVWISCNAPAKVAGKISPIEALRYQNF
                     ASTKTKSRNSTNGGKLHVMAYHNVFRDKKRAFLVFMSLFMGITMILGVNGMIGSMKAE
                     NYVEKYMDYNFEYRDVQFEQYEQPNKEVPQFDEQFVEQIKQIDGVKNIDIQKTVWGGI
                     AFDEADLEEFMKIKYEDSRYKTEGQSYQEMVADLKKYANAGDYGCYITTLDDKAVEEY
                     NTEHPDTPIDIEKFQRGETAISGMDTEYNAPNTALVGKTLSLTADSPDGKATDFLIDG
                     SFYFGDYENNLSYSMGQRKDISIVPDIIYVSEAGMERLTSAPIISGIGIDIKDMNQLE
                     EIDSELQALNGTLTKTEWSYQSPVGIIEEFNQMNYSMNLLGNGAAVLLIVIGLINFIN
                     VMLTGVVARKNEFAVMESIGTSKKQIKKILTLEGGIYALVTTGLIMTLGNAFLLLVAD
                     AVPHIADYAKFEYPFALVICLIFAIFIICLSVPAIVYRAVSKETVIERLHDLGN"
     gene            23565..24230
                     /locus_tag="KRH23_002662"
     CDS             23565..24230
                     /locus_tag="KRH23_002662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HHS5225940.1"
                     /translation="MANIFLLEDDKILSKGISIALEKDGHHVTTAYGYVEALQKYTLK
                     KYDLFLLDINLPDGNGMNFCQKIRQTSQLPVLFLTANDTEEDMLNGYDVGCDDYISKP
                     FSIDVLRRKVSAILKRTITETAQIQYKDLEVDIGKCLVLLKGEEVHLSATEYKLLCYL
                     IQHKGTVVTKAMLLENLWDKDGNFIDDNTLRVNIKRLRQKLKDDNQEYIVTVFGIGYT
                     FGE"
     gene            24233..25258
                     /locus_tag="KRH23_002663"
     CDS             24233..25258
                     /locus_tag="KRH23_002663"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: protein motif:HMM:NF014567.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HHS5225941.1"
                     /translation="MKHFKYIRKILIILEVMIAIALAIVLCFIPMDIFVKAGLLVGVA
                     IFFLIFYLLDHLHNRYLDDMLEELTFLIEELVGKQEVKVFSELEDTLLSRLQHQLLKL
                     RSILITQNQLLDREKKQIKALISDISHQIKTPVASANTFVQLLNDDTLSEEERKEYIA
                     ILQLSLEKLTFLVNSLVKMSRLESGIISLKPEKNSLNDIILQAVKSVYSKAKAKDITI
                     VFDCEQDYILYLDFNWTAEAITNVLDNAVKYTQNGGTVRLNMTEYASYLRLDIIDNGI
                     GIPEEEQAQIFNRFYRGKYSTGVDGVGIGLYLTRDIMTKQKGYIKVISNDTGTTFSLF
                     FRLYVEE"
     gene            25545..25964
                     /locus_tag="KRH23_002664"
     CDS             25545..25964
                     /locus_tag="KRH23_002664"
                     /inference="COORDINATES: protein motif:HMM:NF019886.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HHS5225942.1"
                     /translation="MKPTSFEDAIRLQFDTLMKKVIDKTIKNYERSLTRRNKREVLFC
                     ELPEIMVQSFPVFDEYDLDVADYDVYGMTAHVCDKELCNALDQLSEKRRNTILLFYFL
                     DMSDIEISELMNITRCTSYTRRMTALRQMKEILEKGK"
     gene            25969..26208
                     /locus_tag="KRH23_002665"
     CDS             25969..26208
                     /locus_tag="KRH23_002665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002592280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHS5225943.1"
                     /translation="MEKDVSKCPPYRLISSAANGDEKAIQKILDFYDNYISACCMRKL
                     YDEYGNVRMAVDLELKGLVCHAMIQKIKAFEVEIK"
     gene            26661..27512
                     /locus_tag="KRH23_002666"
     CDS             26661..27512
                     /locus_tag="KRH23_002666"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF012376.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HHS5225944.1"
                     /translation="MKILYVTDLHGDKEKYKKTLEIAIEKQIDVIVNGGDMLPKQCNR
                     HLEQPVFIKQFLREYFKELQKHNIKYLAMLGNDDLLAVDDLFDTVCNEFPNVYNIAGR
                     KVNINGFEFIGMNYILDHPFGCKDRVITEIDYVPQRQLSTFAGTSNEYDYDRIYNWLE
                     YSKTELPYMCDVLNQLPKPDNPQKTVYIMHMPPARLRLGQLLYQDLDIGSVDIYNFLK
                     ERQPLFSLHGHIHESPDTEKGKWCNQIGNTICIQTGQTELFASDMVYAEIDLQHQEFR
                     REVVKVK"
     gene            27567..27713
                     /locus_tag="KRH23_002667"
     CDS             27567..27713
                     /locus_tag="KRH23_002667"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5225945.1"
                     /translation="MEQKVKQDMLKIKDTTFYITSVFSGTVDLQSLIKRLIRSEIEQK
                     NGMN"
     gene            27760..>29406
                     /locus_tag="KRH23_002668"
     CDS             27760..>29406
                     /locus_tag="KRH23_002668"
                     /inference="COORDINATES: protein motif:HMM:NF012464.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HHS5225946.1"
                     /translation="MNSKKMFVCCWKGAEMLKQQTRLRVRLYARLSKDDGDADKESNS
                     IKNQLQMLRYNAKEKGFIVVGEYVDDGYSGTTFNRPDLNRMIKDAMEDTEPSGIMVKD
                     MSRFGRNNAMFMYYVEEIFPNNDILFIALNDDVDTRFDENEMMPFKSIMNEYYARDTS
                     KKIRSVKKTTALNGGFCGSFAPYGYRLDPQNKQKLLIDEETAPIVKRIFELSKQGNGI
                     HQIARILCEDGILIPRAYRAMKNGTLETSTGFKFPTDWVAKNVKMILENQVYLGHMVS
                     HKTQTKSFKNRKLVPVPKEDWIIVKNTHEPIIDEDTFELVQKFISVKKQPNKTRKPNM
                     FVGLVKCPDCGRNMALSGRADSSRWLRCRTYTRNTNLCTSHSISYNALQQIVMNDIQK
                     HIKNMEALGDQFLEEMKELSEKGGNEKIQHLKQSLEVAEKRIEEIDNVIMKLFEQNAL
                     GKISDERFEKMSISYENEQSELKLKRNDLKDKIESEEKKTQSTNQFLETIRKYENVTE
                     LNRAMLVELIDSIYVYQAEGTGQEKTQKVEINYRFLAGSQC"
BASE COUNT         9893 a         4628 c         6570 g         8315 t
ORIGIN      
        1 tattgtgaaa atgtggcata aacagcgaca aacttctttt tacaatctct tataaaattg
       61 aataacatat aatatattaa cggggaacgc tagaaatggt gttccttttc ttatttcaga
      121 cgttcaaaat tgagcgtcta tttttttacc caaaatgaaa ggagcattta agaatgaaga
      181 acatattaaa acgagtatgc acgggatttc tcgcgttggc aacagtaatc actaccctgc
      241 cggcgacaac ggctcatgca gcggaaaaac aatactggac agaatctgat gagcgtgtcg
      301 gtatcgtaga acaggtaatg aatgacggtt ctatcaaggc aacatttaac gagggctata
      361 tgaaagtcga gggcgaaact gcctattgta tcgacattaa cacagctttc caaaatggct
      421 ataagacacg agcagacgca agtacgcgta tgagtgccaa ccagatttct gatgtggctt
      481 tatctattga atatgtaaag cagtatgcag aaaaacacaa agaattaaat tacaaacaag
      541 tctatctatt agaacaggtt gttgtttggc aaagattgag tgtgcattta ggctggcaat
      601 gcgataacgt gcgtgcggca tatagtgaaa tttcaaaggc tacacaagag gaagtgtttg
      661 caggcgcaaa agcctttgta aaagaaaata aaggacgtta tgaatgtggc ggatatatct
      721 attccggcga gggtcaggaa cttggacagt tttgggcgaa gttaaatgtt ggaaatgcta
      781 aacttcaaaa ggtttccagt aatgccggca ttacagatgg caacgccaac tattctctta
      841 ccggtgcgac ttacggtgtc tttgctgata aagagtgcca aaaacaactt gccactctta
      901 cgactgatga aaatggaaat acagatgttg tagaggtaaa agcaggcaca gtctatatca
      961 aagaattgtc tgcgccactt gggtttcagg tggatacaac ggtgtattcc ttaaatgtgg
     1021 aagttggtaa gactgcaacc ttaaaagtta gcgatacacc aaaagtaacc gataccttaa
     1081 ttgaactttt taagattgat atggaaacac agaagaacaa tccacaggga acggcttctt
     1141 tagcgggtgc tgagttcaga tggaattatt atgacggttt ctatacaaaa gataatcttc
     1201 catcaaagcc aacacgcact tggacaacaa aaaccgttga agaaaaagat aagcaaggaa
     1261 atgttcatta catcacaaaa ttagcggaca catacaaagt ttccggcgac gcgttctata
     1321 tgcagaatgg aaaggcagtc cttcctcttg gaacattgac tgttgaggaa gtgaaaagtc
     1381 cgtcaggata tttattagag ggcgcctata tgcaggcaaa tggaagttct gaacagataa
     1441 aaggtgtcta tcttacacag attgcagagg acggcgacct tgcggtattg acaggtgcta
     1501 atcaattttc tgtatcggat aaagttattc gcggtggtgt gaaaattcaa aaacgagatt
     1561 tagaaacagg cgataccaaa ccacaaggaa gtgccacgtt aaaagatact gcttttgaca
     1621 tcatttcctt aaatgaaaat gaagtattgg ttgagggcaa attacacaag aaaaatgagg
     1681 ttgtaaaaac cattcatacg gatatttccg gtgttgcaat gacttcggac aatcttcttc
     1741 cttatggaaa atataagatt tctgaacaga aagcaccaga gggatatttg actgatggtg
     1801 caaaagaaat cgagtttgaa attacagaaa acggtaaaat cgtggattta acggataaag
     1861 accattctat ctacaatcaa atcaaacgcg gcgacattga gggtgtcaaa attggtgcag
     1921 gtacgcataa acgcttggct gatgttccgt tcaaaattac aagcaagacc acaggcgaaa
     1981 gccatattgt tgtaactgat gataacggac agttttctac ttcatcagac tgggcgagcc
     2041 ataagcacaa taccaacaaa ggacagtcaa gtgaagatgg tgtgtggttt ggaacttctg
     2101 aaccggacga cagcaaaggg gcacttccct acgatactta catcattgaa gaattacgat
     2161 gtacaagcaa tcaggggttc aaacttattc cgccatttga aatcgtggtt tcaagaaata
     2221 accatgtggt tgatctaggt acattaactg atgaatacga aaaggaaatt actattcata
     2281 caactgcaac cggtaaagat ggcgaaaaaa caatccttgc aggaaaagag gtaacaatcg
     2341 ttgatactgt gaaactggac ggacttgtga aaggtacaaa gtatcagtta aaaggctggc
     2401 agatggtaaa ggaagaaaat gcagaactta tcattgatgg aaaacgtgta gaaaatgact
     2461 atacctttgt cgctgatgat gaagaaatga aagtggaaat tgcctataca ttcaatgcgt
     2521 ctgctttagg tggcaagaac cttgttacct ttgaagaatt atatgattta agcaatccag
     2581 acgaaccggt caaagttgcc gagcataagg atattgaaga tgatggacag actgtactta
     2641 tcacagaacg cattatccgt attcatacaa cggctgctga tctggacgga gacaaggaaa
     2701 ttcaggcgga taaagaaata actattattg atacggttac tttagagggc ttggaagtcg
     2761 gtacaaaata tcagttaaag ggctggcaga tggtaaaaga agaaaatgca gaacttttga
     2821 ttgatggaaa gcgtgtagaa aatgactata cctttatcgc agataaggaa aacatgacag
     2881 tagaaattgc atttaccttt gacgcctcta ctcttggtgg aaaacagtta gtaacctttg
     2941 aggaactata tgacttgtca aatcctgatg aaccgaagaa agtggcggaa cacaaagata
     3001 ttgaggacga tggacagaca gtaaccatta aggaaattcc agaagaaccg gaagttcctg
     3061 aaaagccgga agaaccaaca acaccggaga aaccatctca accaacagac agtccaaaaa
     3121 ccggagataa cacaaatgtg atggcgtttg ttgtgctgtt gcttgcttct gccggtatgc
     3181 ttagcggtac atatctttgg aaaaagtatc gtaagaaaga ggactaaatc atggcaatta
     3241 cattagggag tttgtttgat gggattggtg tatttccttt ggcagcctcc aactatggca
     3301 ttgttccttt atgggcgagt gagattgaaa aagttcctat ttctatcaca aagaaacact
     3361 tccctcaaat gcagcatttg ggggatatta caaaacttga cggtgcgaag ataccacccg
     3421 tgcatatcat cacatttggt tcgccctgtc agaatttatc aacgatcgga gcgcgtgagg
     3481 ggcttgccgg tgcaaaatcc ggtctgtttc atcatgcaat ccgtatcata caggaaatga
     3541 ggtgtgctac tgatggcaaa tatccagtta tcgctgtttg ggaaaacgtt agaggagcgt
     3601 tttcttcaaa caaccggttg gactttagag ccgtgctgga gtcgttcgca gataccgaaa
     3661 ttccaatgcc tgcttctcga agatgggcaa acgccggaat ggttcgaggg ggtaaagttg
     3721 atgtgtgctg gcgactcttg gacgctcagt attggggaga acccaccctc tctcaaagaa
     3781 gaaaacgtat cttcgtcgtg gcggatttta gaggacagcg tgccgcagaa atattattta
     3841 aaccccacaa attgcacgca catattgacc ctagccgaaa gagctggctg tcctccggcg
     3901 aaagaaatcg aatatctgtt aatcaagcaa gggggaaaat accagtccta tgtccctttg
     3961 aggaaagaag aaccagagga agtgcaaaat atcaggacac gcaggggttc gtcagaagtt
     4021 ttggacggcc aaatgaccct tttcccacct tattagccgg tggtccgggt gtattctcct
     4081 tttggtatga gggcgaagaa aaagagggat ttatccgtta tctgacgccg attgaaagtg
     4141 aaaggctcat gggcttgccg gacgattgga caaagtatgg caatacagga actatcaaca
     4201 gcgactatgc aagatggcga gcgttaggaa atgcgattgc tgttccctgt gcagaacata
     4261 tcatggcagg gattgcagaa gtcttaaagg aaagtgagga ttgagaaaat gaaaagacga
     4321 tcaagagcac cgcctagatg ttgaatgatt tacacaagcc atttatgaaa ctgtttcttt
     4381 gtcgttagtt tttgaaaaaa agtgatgaga aaaaacagta cactaagggg tatggggaaa
     4441 tgtagtgtcc ccatgcttta tcaggaaaaa tagaaaacag agaaagaaaa gaggtaaaac
     4501 atatatggaa ttaaaatttg tagtgccaaa catggcacag acttttggaa acttggaatt
     4561 tgcaggcgaa aacgaagtcc gtcagcagag agtcaatgac agaatgacgg ttgtaagccg
     4621 cagttataac ctgtactctg atgtgcagcg tgccgatgat attgtggtta cacttccggc
     4681 aaaagctgga gaaaagaact ttcagccgga acagaaagtg aaactcatta acccacgcat
     4741 taccgcagat ggctataaca tcaatgggcg cggatttaca aactatatct tactggctga
     4801 tgatatgtta ccggtggaaa gcaaataaag gaggatttta gactatgaga ttagcaaacg
     4861 gaattataat tgataaagaa aaaacattcg gacagttgaa gttttctgcc ttgcgtcgtg
     4921 aggttcatgt gcaaaatgag gacggaacaa tcagcgaaga aatcaaggaa agaacctatg
     4981 atttgaaatg tcgtgaacag ggacgcatga tacaggtgtc tgtaccggca aatattccat
     5041 tgagggattt tgagtataat gcggaagtgg aacttatcaa tccggtggcg gatacggttg
     5101 caaatgcgac ctatcgaggt gcggatattg actggtacat caagtgcgac gaccttgtat
     5161 taaagaataa aggacagaca ccaaacaatc caaatgcagc gcctaaaaaa taggcagata
     5221 aggagtaggt atggctttat tcaaatataa aggaaatcgt atccgcgcaa gcgatcagca
     5281 tttggtctat cgcttttgta tgggcacttt gatactgctg ttcctatgta tcgtggtgtt
     5341 gctgaaccta aaacagattg ttcatacaga ttggggaaat tttaatctga cagagatgga
     5401 atttcccctt tcttcctaca acttcataac cttactgata gcggctggtg tttgtgcatt
     5461 ggtcgctttt ctctattatc ggttttgtta tgacagtttc aagaagatgg tccatcggca
     5521 aaagttggcg cgcatgatat tggagaataa atggtatgaa gcagaacagg caaaacaaag
     5581 cggatttttc acagacttgc catcttccac aaaagaaaca atcacttggt ttcctaaaat
     5641 ctattatcag atgaaaaatg ggttactgca tattcaatgt gaaatctcta tgggaaagta
     5701 tcaggagcag cttcttaatc tggaagataa actggaaagc gggctgtatt gtgaaatgac
     5761 agataaggtg ctgcatgacg gatatattga atataccctg ctttatgata tggtcgcaaa
     5821 ccgcatttcc attgaggaag tcaaggcgga gcatggcgga ctaaaactga tgaaaaatct
     5881 tatttgggag tatgacgcac ttccccacgc tcttattgcc ggtggtaccg gtggcggaaa
     5941 aacctatttt ctgcttacca tcattgaaac gctgctacag accaatgcgg tactttttat
     6001 cttagacccg aagaatgccg accttgcgga cctgggaaca gctatgccga atgtctatca
     6061 tacaaaggaa gaaatgataa attgcgtcaa ttccttttat gatggtatgg tttcacgcag
     6121 cgaagaaatg aaacagcacc cgaactataa aacaggcgaa aactatgcgt atttaggact
     6181 ggcgcctcac tttcttatct ttgatgaata tgtggcattt tttgaaatgc tgggcgctaa
     6241 ggaaagcatg aatttattaa gtcagttaaa gaagatcgtc atgcttggca gacaggcagg
     6301 ctattttctc attgtggcat gtcaaagacc ggacgcaaag tattttacag acgggatacg
     6361 tgataatttt aattttcgtg ttggtttggg gcgtatgagc gaacttggtt atggtatgct
     6421 tttcggttct gatgtgaaaa agaaattctt tcaaaagcgt atcaaagggc gtggctactg
     6481 tgatgtggga acgagtgtca ttagtgaatt ttatacacct ttagtaccaa aaggacacga
     6541 ttttctaaaa gagattggca ggcttgcaag taaaaggcag gttctgtttg aagaacaagg
     6601 aaaggacaat gacaatgtgg tggaataacg aaaacaatgc aagaagaacg tacagcaaca
     6661 aagccggtcg cggtcagcag cgcgtacaag accgcgtcag accggcgtgt tgtggtgcag
     6721 ggcttgccct gcgccaccgt cattgcccct cggtatctaa cagaggggca caaaaaaaca
     6781 ggaaacagtc caaaaaagtc gtaaaagact gataaacagt ggacttttgc ttgttttaag
     6841 gcaaagtgat aatgcctata aaatatcaca ttttataaga tgggagtgat gataactgaa
     6901 tgataaagag tggttagaag catttaagga aaagcgagcc ttatatggtg ttacacagtt
     6961 acggcttgcg gtcatggcag gtattagccg tgagcattta agccgtattg aaagtggcaa
     7021 ggtatcgctg accttagaaa tgaaagaaaa attattgaca gccttagaaa aattcaatcc
     7081 tgatgaaccg ctatttcttt tgtttgatta tgtgcgtatt cgatttccca caatggatat
     7141 aaagcatatc atcaaagatg ttttaagact gaatatacag tatatgttgc atgaggattg
     7201 ggcgtatttc agttacacgg aacaatacta tatcggcgat gtctttgttt atacttctgc
     7261 tgatgaagaa aaaggtgttc tgttggaact gaaaggcaaa ggctgtcggc agatggaaag
     7321 ttatctgctt gcacaggagc ggagttggta tgactttctg atggattgtt tggttgaggg
     7381 tggcattatg aaacgcttgg atttggcaat caatgacaga actggaatac ttgatatacc
     7441 ggaactgatt gaaaagtgta aaaatgatga atgtgtttcg gtatttcgtc atttccgctt
     7501 ctatgcttcc ggcgagattt cccatcagcg agaacgcaac cacaaagaaa tgggaacgac
     7561 catgtatatc ggctctatga aaagtgaagt gtacttctgt atttatgaaa agaactatga
     7621 gcagtacatc aaggcgggtg ttccgttaga agaagcacct gtgaaaaatc gtttcgagat
     7681 acgattaaaa aatgaacgtg cctattatgc ggtgcgagat ttgctgacct attatgacgc
     7741 agagagaacg gcattttcta tcatcaaccg ctatgtgcga tttgtagata aggaagaaaa
     7801 caagccagtc agcgagtgga aactgaatga aaaatgggct tggtttattg gcgaaggcag
     7861 accgcctttg aaattgacaa caaaaccgga gccgtacacg ttagggagaa cattacgctg
     7921 gatttcaaga caggttgacc cgacacttct tatgttggaa gaaatcgcaa agaaaacagg
     7981 tgtcaattac ttaaaagaaa tacgccagta cacaaaactg acagaaaagc atgagcagat
     8041 tatccgtcag cagacaacaa cgatagaaga aatcgtgtta agtgatgaag aaaggaatga
     8101 gaaagatgtg ggtatttttt aaggatttac tgctggtatc tgttggaatg ggtatcggcg
     8161 tagtcctgat gtgtatatta caagtcggca aggacgctga caatgtgatg aatgaattaa
     8221 aagaaaataa agaaagtgag gaacagtaaa tgaatttcgg gcaaaatttg tatcaatggt
     8281 ttttatcaaa tgcacagtct ttagtgctta tggcaatcgt agtaatcggt atctatttag
     8341 gatttaagag agaattttcc aaactgatcg gtttcttaat cgttgcttta atcgcggttg
     8401 gattggtatt caacgccggc ggtgtgaaag atgtgctttt ggaattgttt aataagatta
     8461 tcggggcata gaaagttatt gttgatgtaa tatgtgaatg gtataatatg gatatgtcaa
     8521 aataaaactt taggaagtga aaaaatgatt ggaatatatt taagtggtac gggaaataca
     8581 aaacattgca ttgagaaact ggtaggattg atagataatt ctgcaaaagt atttccgtta
     8641 gaaatgccta atcttattga ggaaataaag aaaagcgaca cgattatttt gggatacccg
     8701 acacaatatt caaatgcacc ttatatggta agagatttta taaaacaaaa tagttctttg
     8761 tggaaagata agaaaatatt ttgtgtagca acaatgggtg cttttagtgg agatggtgcc
     8821 gggtgtactg ccagactatt aaaaaagtat ggggcttcca ttttaggcgg acttcatata
     8881 aaaatgcccg actctgtatg tgatagtaaa ctacttaaaa agacacttga agaaaacaga
     8941 gaaatagtaa agcaggctga taaaaaaata gaacttgttg cagaaaaaat aaaacaaggg
     9001 caatatacca aagatggtat ttccttcttc tcccatctaa tagggctatt tgggcaaaga
     9061 ttgtggtttt acaataaaac aacaggatac acggataagt taaaaatcaa tcaagattgt
     9121 attggttgca atttatgtgt ttccttgtgc cctatgaaaa atatttctat tcaaaatgga
     9181 aaggctgttg ccggcaatca atgtacgatg tgttatcgtt gcattagcca ttgtcctaaa
     9241 aaagcaatca cgcttttagg aaatcaggta acagaacaat gtcagtatga aaaatactgt
     9301 gaataaaatt ctctagtaaa tttgatatat ttatatacgc aaagcagtta gtcttttaga
     9361 ttggctgctt tttctgtgcc taaatttcag attggagtga tgatatgagc gatattttta
     9421 aggatatgca aatgaaaaca ggttgcgagt acatttccga cctgccctct cacaagagaa
     9481 ttgtttggaa agaattgaaa aaacaaaatc tttcccagta tgacaaaaaa cagttagagg
     9541 atttttccaa ctatgtgttt gggttatcct atgacacttt acaggctgtt ataaagcagc
     9601 agaaaggacg tgaaaaacga gtatgaaaga attacgtgta tgtatggaaa gcgcgcttcc
     9661 tgatgaagaa gtgaaaaaag catggtttac cttgccgatt gatgaagaag atgtattaga
     9721 aaaattgggt gttgatgtgg aaagtgatga ttaccgcatt attgaaactg atgtaccatt
     9781 caagacagat ataaaagaaa atacaagcgt ttggcgtctg aatgatctgt tctatacctt
     9841 tcttacgctt cctcatttta tgcagttaga ttgtgagtta ttgttggaac gattgccgag
     9901 tttggacttg ctacacgcct atcacgacgc aatccatttt tatgagggtg ctgtcagcat
     9961 gatcgaggtg gcaaggcgaa aaatgataga atacaattcc gtttcggaag aagccataca
    10021 ttatatggat ttagaaaagt ttgccggata tttggaagaa aacggacgct ttctaaaaac
    10081 ggagcacggt atctatcagt tgccgtagga atgaggtggt atgtatgact gatgatatgc
    10141 aggtatatat cgcaaatctt ggaaaataca atgagggtta cttagtcggc gcttggttct
    10201 cttttcccat tgatgaggaa gatgtgaaag aaaagattgg tttgaatgag aactacgaag
    10261 aatatgcaat ctatgatacc gacaactttc ctatggaaat cggggaatat gtttcgattg
    10321 aagaactcaa ccgtatgtat gaaatgatgg aagatttgcc ggagtacgtt gtggaatgtc
    10381 tggacgagtt tgtcgggcat tacggctctt tggaagaagt ggcggaacat aaagacgagg
    10441 tttattttta cccggactgt gaaaccatga cggacgttgc ctactactac attgatgaat
    10501 tgcagacgct tggagaaatt ccctcacaat tacaagatta tattgactat gaggcctatg
    10561 ggcgcatgct ggatatggtt ggaacattta tttccacaag ccgaggtatg tgcgagatac
    10621 catattaaaa gaagaacgga tacggacagt ctgaaatacg gctgtccttt cctttataaa
    10681 aaacacaatg gaaaggagtt ttagtaaaaa gatatgaaga aaatcaaaag ttatacagga
    10741 atatggaacg tggaaaaagt gctgtatgct atcaatgatt ttaacctgcc gtttcctgtt
    10801 acctttacac agattacatg gtttgtgatt acggaattta tcgtgattgt atttgcggat
    10861 ataccaccgc tttccatgat cgagggtgct ttcctcaaat actttggtat tccggtggca
    10921 ctcacttggt ttatgagcca aaagactttt gatggcaaga aaccatacag ttttctaaaa
    10981 tcgcaactct gtttttattt tcgaccgaaa gtaacgtatg caggaaaagc cgtaaaactg
    11041 cgtacagaaa aattccatga aacgattacg gcagtaagga gtgtgaagta tgttcccgat
    11101 taaatatatg gataacaacc ttgtgtggaa caaggacaat gaggtattcg cctattatga
    11161 actgatacct tataactatt cttttctatc tgcggaagaa aaatttatcg tgcatgataa
    11221 tttccgccaa ctgattgcac aatcccgtga gggtaaaatc catgcacttc agattgcaac
    11281 ggaaagttcg attaagaata ttcaggagca gtcaaagaaa ttagtgagcg gaaaacttcg
    11341 tgatgtggca atccaaaaga ttgatgaaca gacagacgcg cttgtttcca tgattggcga
    11401 tacgcaagtt gattatcgct tctttcttgg atttaagtta atggtgcctg atgaaacgct
    11461 caatctcaaa aatatcaaga aatctgcatg gctgacgttt caagagtttc tccatgaagt
    11521 gaaccatacg ctgatgaatg attttgtatc catgccaaat gatgaaatca accgttatat
    11581 gaagatggaa aaattattgg aaaataaaat ttctaggcgt tttaaggtgc gacgtttgga
    11641 agtgagtgat tttggttatt tgctggaaca cttgtatggc agagatggga ttgtctatga
    11701 agaatatgat tatccattac caaagaagaa actgaaaaaa gaaacgttga taaaaacgta
    11761 tgacctgata cgaccgacaa gatgtctgat agaagaaaat cagcgatatt taaggctgga
    11821 acatgaggac agcgaaacct atgttactta ttttacggtc aatgcgattg ttggagaatt
    11881 ggattttcca tcaagtgaaa tcttctatta tcagcagcaa cagttcacat ttccggtgga
    11941 tacttccatg acggtggaaa tcgtggaaaa cagaaaggca ctctccactg ttcgcaataa
    12001 gaaaaaggaa ttgaaagatt tggataacca tgcctttcaa tccggcagcg aaacaagttc
    12061 taatgtggtg gacgctttag acagtgtgga cgaactggaa acagatttag accaaacaaa
    12121 agaaagcatg tataagttat cctatgtagt acgtgtctgt gctgatgatc tggacgagtt
    12181 aaaaaggcgc gctgatgaag tgaaagattt ttatgacgat ttgagtgtga aactggtacg
    12241 gcctgccgga gatatgctcg gacttcactc tgaattttta ccggcaagca agcgttatat
    12301 caatgattat gtgcaatatg tgaaaagtga tttcttggca gggcttggtt ttggcgccac
    12361 acagcagtta ggagaaaaca cagggattta tatcggctat tccgtagata cgggaagaaa
    12421 tgtgtatctc caaccctcac ttgccagtca aggcgtaaaa ggtacagtta ccaatgcgct
    12481 tgcttctgct tttatcggaa gtcttggcgg tggaaagtcc ttttgtaaca atctgcttgt
    12541 gtattactct gtgctgtttg gcggacaggc agtgatttta gacccaaaat ccgaaagagg
    12601 aaattggaaa cagacgttgc cggaaatcgc tcacgagata aacattgtca atctgacaag
    12661 cgataaagaa aatgcaggac ttcttgaccc ctttgtcatt atgaaagatg ttgaggacgg
    12721 agcgactttg gcaaaagaaa tcctgacttt tttaaccggt atttctaccc gtgacggaga
    12781 aaagtttccg gtgctgattc gtgccattgg taaagtcaaa gacagtaagc agagaggact
    12841 tttgaatgtg ataaaagaac tgagaaaaga agaaacggtt atcgcaaaca atatcgcaga
    12901 ccatatcgaa agttttgttg attatgattt tgcacaactg ttattctcgg acggttcggt
    12961 agaaaatgca atcagtttgg ataatcagtt gaatatcatt caggtggcag atttggtgct
    13021 accggataaa gatacttctt ttgaggaata cacgaccatt gaattgttgt cggtggcaat
    13081 gctgattgtc atttctacct ttgctttgga tttcattcac agcgaccgtt ctatttttaa
    13141 gattgtggat ttggacgaag catgggcgtt cctcaatgtc gcacagggag aaaccctttc
    13201 taacaagttg gtgcgtgccg gacgagccat gcaatcaggt gtttatttcg ttacccagtc
    13261 tgcttatgat gtatcaaaag aaagtctgaa aaacaatatt ggcttgaagt ttgcatttcg
    13321 cagtaccgac atcaacgaga taaaacagac cttagaattt ttcgggattg ataaagagga
    13381 cgagaacaat caaaaacgct tgcgtgatct ggaaaacgga caatgtttat tacaggattt
    13441 atatggccgt gtcggtgtgg tacagataca ccctgttttt gaagaattgc tccatgcctt
    13501 tgatacaaga cctccggttt caagagacga ggtggtgtga tgaatgaaag atggaaagtt
    13561 tcaaagataa caaaaaagaa tatcaaatct atcaaacgat atatgacaaa acaaaaagta
    13621 ttgcgtttta tcaaaatgac gcttcttgtg attggaataa cattgatact gctctcttta
    13681 cttggaacgg tggcacaggc ggcaggattg gttgatgata cggtcagcgc agaaaatctc
    13741 tactccaaat atccgttaca gaattatacc ctagattttt atgtggataa ttcatggggc
    13801 tggctgccgt ggaactggct tgatgggatt ggaaaaagtg tgcagtacgg actttactgt
    13861 attaccaatt tcatttggac aatcagtcta tatttaagca atgccaccgg ctatgtcgta
    13921 caagaagcct ataaactgga ttttatcaat gatatggcag acagtatcgg aaaaagcata
    13981 cagacccttg caggtgtcac gcagaatggg ttttcttcga caggatttta tgtgggattt
    14041 cttttactga ttatcttgat cgtgggaatt tatgttgctt ataccggact gataaaaaga
    14101 gaaacgagca aggcatttca tgctgtgatt aactttgtgg tggtgttttt attatcggcg
    14161 tcttttattg cctatgcacc ggactatatc aaaaaggtca atgagttttc cagtgatgtg
    14221 agcaccgcag cacttgatct aggcacaaaa atcatgcttc caaactcgga cagtgaggga
    14281 aaagacagtg tagatttgat acgtgacagt ctattctcta ttcaggtgga acagccgtgg
    14341 ctgctgttac agtttggaaa ttccaacaag gaagaaatcg gtgcggaacg tgtggagtcc
    14401 ttagtatctg taagtcctga tgaggaagat ggaaaaacaa gagaagaagt tgtgaaaacg
    14461 gaaattgaag ataacgacaa caccaacctt acgataccgc aggtcatcaa tcgtttaggt
    14521 atggtgtttt tccttttgtt cttcaatttg ggaattacga tatttgtgtt tttacttaca
    14581 ggtattatga ttttcagtca gatactcttc attatctttg ccatgtttct gcctatcagt
    14641 ttcctgcttt ccatgatacc ggggtatgaa agcatgacaa aacaggcaat cgtgcgggtg
    14701 tttaatacga ttatgacaag agcaggcatt acgcttatcg taacggtagc gttcagtatt
    14761 tccagtatgt tttataacat ttccacagac tatccgtttt ttatgattgc attcttgcag
    14821 attgtatgtt ttgcgggaat ttatatgaaa ttaggcgatc tgatgaatat gtttagtcta
    14881 aatgccaacg acagtcaggg agtggcgcgc cgtatcttcc atagaccata tatgtttatg
    14941 cgccatcggg caagaagaat ggaacgcaga atgacacggg cagcctcttt aggcgttgcg
    15001 gctggtacag gtgcgatggc aggaagtatg gcaggaaaac aacagacaca ggcaaatgaa
    15061 cagcgttccc gtaataatgt ttccaaaggc tctttcaaag atgttcccca aaaagccggc
    15121 gctatggtag gcgcagtgat ggatacgaaa aacaaaatga aagagaaagc cggtgctgtt
    15181 cgtgaaaata tcaaggatat gccgttgcaa gcgtcttatg cggttcattc cgtcggcaga
    15241 caggcgaagg aaagtgtttc tgattttaag cgcggtattg tgcaggaacg agaacacaga
    15301 caatccggtc gtgaggaaaa gcgtcagcag catagacaga acattgcgga taagcgcatg
    15361 gcattacaaa aaatgcagga acagtctgga atacataaga aacatgaaag accggtggcg
    15421 gttttcaaag aaaatgcgtt agaaaacagg tcaaaagtac aggaagtgaa acgaccggta
    15481 acgagcgaaa aatcaaatgc accggttata aaaagacaac agaaaatgaa tgtggaacag
    15541 attgaaaaag taagaccact ctcctcttat gagaagaacc atcaaaatga tggtgcaaat
    15601 agacacagta taaaatcaca atcggtacag acggtgcaaa aatcacaggt gcataaggac
    15661 acaaaccgta aggtcgtatc aaagaaagga cagaagaaaa aatgagatta aaacaggtgt
    15721 tactattggg aagtctgttc ccttttctac tggcagtaac gctgttcttc ggtgtacttg
    15781 tgagcgcgga taatgatgat agtggcggcg actattcttc cggtgttacc ggaatgaatt
    15841 tatccgcaga ggtgttgaaa catcagccta tggtggaaaa gtatgccaaa gaatacggta
    15901 tatccgagta cgtcaatatt ttattggcta tcatacaggt ggaaagcggc ggtacagcag
    15961 aagatgttat gcagagttca gaaagtcttg ggttaccgcc taattcctta gatacagaaa
    16021 gttcgatcaa gcaggggtgc aagtattttg cgtctctgct ttcttcctgt aaagaacaag
    16081 gaataaccga catcaatgtg gcgatacagt cttataactt cggcggtggt tatgtgggat
    16141 atgttgcagg caatgggaaa aagcatacat acaatctggc ggaaaacttt gcgaaagata
    16201 aatccggcgg aaagaaagta acttatacga acctgattgc cgtaaaaaag aatggtggct
    16261 ggagatatag ttatggcaat caattttatg tggaacttgt caatcagtat ctttatgtta
    16321 cgcagtttga tgatgaaacg gtgcaggcga ttatgaatga agccttgaaa tataacggct
    16381 gggaatatgt gtttggcggt tcttcctcaa ccacttcctt tgattgtagc ggactgacgc
    16441 aatggtgttt tggaaaggct ggtatctctt taccgagaac agcgcaggca caatatgacg
    16501 caacacaaca tatcccgatt gcacaggcga aaccgggcga tttggtgttc tttcacagta
    16561 cctacaatgc gggaagttat gtaactcatg tcggtatctt tgtttcgccg acacagatgt
    16621 atcatgcggg aagttccggg attggatata ccgatttgac aagtagttac tggcaacagc
    16681 atttgattgg cgccggacgt gtaaaacaat agaaagtgag gattttcaaa tgaaatggaa
    16741 gaaaaagaaa cagacagaaa ataaacaaga aatgaaagaa aaaaagaaac ctaccttaaa
    16801 agtgggtacg cataaaaaat ctgtgattgc cttatgggca gtgctgatcg tgagtgtcag
    16861 ttttggagta tataaaaatt ttactgccat tgatatgcac acagtccacg aaaaagaaac
    16921 ggtacaactt cgattgaatg ataccaacgg gatagaaaat tttgtcaaga atttctgtaa
    16981 agcctattac acatgggata acagcaagga aacgttggag aagcgaactt cttctatcaa
    17041 tgggtatctg acagaagaat tacaggtgtt aaatgcggat accatcagaa cagatatacc
    17101 aacatcttcg accgttagtg atgtgctgat ctggaatgtg gaacaatccg gcaatgatga
    17161 atatgaggta ttatatgagg ttgtgcaatc catcaaagag ggcgaccaaa caagaagtgt
    17221 gcgttcttcc tatatggtta cggttcatgt agatacaaag ggaaatatga ttatcgtaca
    17281 aaaccctacc ctagcgccta tgatggaaac atcagactat gaaccaaaga cggtagaaaa
    17341 tgacagtcag gtggacgcgg atacagttag cgacgctacc gcatttttag aaacattctt
    17401 taagttatat ccaactgcaa cggataaaga acttgcttat tatgtggaag aaaatgtgat
    17461 ggaaccagtg cagcgagaat atcagtttgc ggaagtttta aatcccgtat ttacaaaaga
    17521 cggcgataat atcaaagtga atgtatccgt gaaatacttg gataatttaa caaaggcgga
    17581 acagatttca cagtatgaat tgatacttca taaggatagc aactggaaga ttgtaggata
    17641 aatgatatta aagcgtgtat gtctgaaaag aggtacacgc ttttcaaaaa acttcaatta
    17701 ttatgataag agagccttga aaaaaatggt caatgactta aaataataat tgaccagaat
    17761 agtcaaagtg aggttgttgc aatgaatgga tatgagaaat ttttagaact tcctaatgaa
    17821 aaacaattaa gaattataaa tgctggattt gaatacttcg gtaaatatgg gtataaaggt
    17881 gcaaatacag aagatattgc gagcagagct gaaatttcta aaggattgtt attttactat
    17941 tttaaaaata aagaaagtta ttatttgttt ttatgtgaat tttgccaaaa tttaatgctg
    18001 aaaagttttc aagaaacgaa ctttcaagaa ataacagatt tttttgaact aattgatttt
    18061 gcaacaaaag caaaactaaa aataatagct gaatatcctt ttataacaga cttttcggtt
    18121 aatctcattg cagataaaag tataaaacaa ggaagtaaaa gtgaagaata tgtaaacaat
    18181 gctatatata attcctttga tatttatttt aagaatattg actttacgcc atttaaagaa
    18241 gaaatagatg taaaaaaaat atatcaaatg atgttatggt tgtccgaggg atacataaat
    18301 gaaaaaaaga gaatgaatat gcctgtaatt ttggaagatt ttttagttga atttgcgtca
    18361 tggaaagcac tgtttaaaaa gatgtgttat aaggaggaat atttatgaat gtaatagaaa
    18421 tcaacaatct aacaaaagat tttggaaata ataaaggaat atttgatttg tccttttctc
    18481 taaaacaagg agaaattgta ggctttttag gttctaatgg tgctggaaag acaacgacta
    18541 tcagacattt aatggggttt ataaaagcaa acacaggttc agcaaaaata gcaaatatgg
    18601 attgttttca caatgcacat ttagttcaag agaaaatcgg ttatcttccg ggggaaattg
    18661 catttatgga taatatgacg ggagaagaat ttattcaatt tatggcagat atgaaaagca
    18721 ttacagattt acaatatgca aaagaattga ttgtatattt tgatattgat acaaaaatca
    18781 aaatcaaaaa aatgtctaaa ggtatgaaac aaaaaatagg cttaatcatt gcatttatgc
    18841 aagatccgcc tatcttgatt ttagatgaac caacaacggg gctagaccct cttatgcaaa
    18901 cgaagtttgt tgatttgata aaaaaagaaa aggctaaagg gaaaacgata ttgatgtcat
    18961 cacatatctt tgaagaaatc gaaaatacgt gtgaaagaat tgtaatgata aaagatgggc
    19021 gtttggtggc agacgagaat ataaatacta tgaggaataa aatgaataag cattatgaaa
    19081 tttcattttc aaatatggaa gatgcaattc attttcaaga attatattct acaaatagtt
    19141 atcgaaaaaa caatgtggtg tatttattgt caaatcaaaa tatcaatcac ttaattcgtg
    19201 aattaggtaa attcaatatt gaagatataa atgcaagaca ccaaacatta gaagaagtat
    19261 ttatgaaata ttacggaggt agtgtaaaat gagtattcca ttactaaaaa tagagttgaa
    19321 atcaaacagt aaaattattt tgttattttt agcgattatt actctttatg ctggaattat
    19381 aacagccatg tacaacccgg aattaggtgc tggaataaat gaacttgcta agagtatgcc
    19441 acagtttttc gcagtttttg gaatggaaaa cccagggaca acactattag atttcttaaa
    19501 caattatttg tatggtttta tcttaatatt gatacctttt atatacataa tcttaatgtg
    19561 ttacaaatta gttgctaaac atattgataa aggttctatg gcatatttat taaatacgca
    19621 ttatagccgc attcaaatta tccttactca atttatagtt ttagtgattg gattacttgt
    19681 tttggtctgt tatgcaactg gtttgattat ttttattagt aatctaatgt ttaagggaga
    19741 aatggaaatt ataaaatttt tgctcgtaaa tttaggtttg ttcatacttg aagtattttt
    19801 atcaacactc tgttttatgt ttgcttgttt attcaatgaa cttaagtttt ccattggact
    19861 tggtgcagga ttgggaatga tttttttctt agtacaaatg ctatcacaag tgagtgatga
    19921 tatagaattt ttaaaatact ttaccccttt aacactattc agtccagaaa atataattaa
    19981 atatgatata gaaagtttta tgtatctagg cgtattgttg attagtgcag ttgtgttttt
    20041 tgtcataact atgaaaaaat ttaaaaaacg tgatttgtca ttgtaaatta aaagacaagt
    20101 tattagcatt gcatgactaa aaatgagtta taaaaaatgc taaaaatagg agtttgaagt
    20161 atccataata aaaaagtgaa atttatttcc aaactgtaag aagattgtaa gaagtggttg
    20221 ttataatgaa actgtaaaag aaatatatga caggaggttt ttattatggc tatacttgaa
    20281 acaaaggatt tgaaaaaaat atatggtagt ggagaaaatg aggttcacgc tttggacggc
    20341 gtgtcgattt cggtggaaga aggcgaattt gtcgctattg tcggtacatc gggaagtgga
    20401 aaatctacat tactcaatat gcttggcggg ttagaccgtc cgacgtctgg tagtgttgtt
    20461 gttcgaggaa aagaacttat gcaaatgaaa gacgaacaat taacgatttt cagacgtaga
    20521 aatgtcgggt ttgttttcca aaattacaac ctgcttccta ttttgaatgt gtatgaaaat
    20581 attgtttatc cgattgagat tgacggcagc aaggtagata aagaatttgt cagacagatt
    20641 attcacaatc ttggtttgga acgcaaacta aaaaatatgc caaacaatct ttctggcggg
    20701 caacaacagc gtgttgcgat tgcgagggct ctagcgacaa agccggcaat tatcttggcc
    20761 gatgaaccga ccggaaactt ggactcaaaa acaagtatgg acgttattct tcttatgcag
    20821 tctatcagta gagaatttaa tcagacaatc cttatgatta cacataatga agaaattgct
    20881 caaatggcag accgcattat ccgtatcgaa gatggaaaag tcgtatcggg aggtgtaggt
    20941 tatgcacgat aatcgaaata aagaggtcat aaaacgtgta gaaaaaggta tgatgaaagc
    21001 caaccgcacc cgtaacattt ttgcggttgt tgctgttgcc cttacaacgt ttatgattac
    21061 aacgattttc agtttgggaa ttaactacaa agaaaatatg gaactaatgg aagttcgtac
    21121 ttccggcacc aatgcaaatg tttcacttac catgccgaca aacgagcagg aaaaagaaat
    21181 ccgtgattta gattatgtgg atacggtcgg tacgcaatat atgattggct ctgttgcagg
    21241 aaaaaacgaa gcagaccgcg accttgcgat tgctatgcaa tattatgaca atacagaatg
    21301 ggaaaagcat tataaagaag caatcagcaa tatcaatgga aagtatccga aaaaagaaaa
    21361 tgagattatg ttgtctgagg acgcactttc tcaattaggc attaaagagc caaaacttga
    21421 tatggaaatt ccattgtctt atgtttcaaa agatggagaa cagaaagata cctttacatt
    21481 aagtggttgg ttccattctt atacgggaac aggtatggca tttctgtccg aaagttattg
    21541 tcaggaacat ggatatacaa tgcaaaatag tggtgttctt tccatatctt tagacaaccc
    21601 aaaagataat ttttatgaca tacaagacga tattacattg aatgaaaatc aaacctttca
    21661 aggctcagtt tctatgtcat catcaaatgg ctctgtctat gcaatgatta ttcttttggt
    21721 attctttatc ataggcagcg gttatctttt gatttataat gtactttata tttccatttc
    21781 aagagataca cgcttctatg gattgataaa gacattagga acaacagaaa agcaaatcaa
    21841 aacattagta aaacgacaag cgttaacctt tggctgtatc ggaataccga ttggtgttat
    21901 tttagcaggt gtgctttctt ttggaattgt tccggttatt ttggaaaatg cgtttgatag
    21961 tggaaagtct attatggacg cagaaatgtt tttccaccct agtatcttca tactgtccat
    22021 tattttctct gctttgaccg tttggatttc atgcaatgca ccagcaaaag ttgcaggaaa
    22081 gatttctccg atcgaagcgt taagatacca aaattttgct tctacaaaaa caaaaagcag
    22141 aaattctacc aatggcggaa aacttcatgt gatggcatac cataacgtat tccgagataa
    22201 aaaacgtgcg ttccttgtgt ttatgtcctt gtttatggga attaccatga ttttaggcgt
    22261 aaatggtatg ataggaagta tgaaagcaga aaattatgtt gaaaagtata tggattataa
    22321 ctttgaatac agagatgttc aatttgaaca atatgagcag cctaataaag aagtaccaca
    22381 gtttgatgaa cagtttgtag aacagattaa gcaaatcgac ggtgttaaaa atatagatat
    22441 tcaaaaaaca gtatggggcg gtattgcttt tgatgaagca gatttagagg aatttatgaa
    22501 aatcaaatat gaggacagca ggtataaaac tgaggggcaa tcgtatcaag aaatggttgc
    22561 agaccttaag aagtatgcca atgctggcga ttatggttgc tatattacaa cgctcgatga
    22621 taaagccgta gaagaataca ataccgaaca cccagataca ccgattgata tagaaaagtt
    22681 tcagcgtggg gaaacggcaa tttcaggaat ggatacggaa tataatgcac cgaataccgc
    22741 attggtagga aaaacattat ctttgactgc ggatagtcca gacggtaaag caacggattt
    22801 tttgattgat ggttcctttt attttggaga ttatgagaat aatctttcat atagtatggg
    22861 tcagcgcaaa gatatttcta ttgtaccgga tattatctat gtcagtgaag caggtatgga
    22921 acgtttgaca agcgcaccta ttatttcagg aattggtatt gacattaaag atatgaatca
    22981 attagaagaa attgacagtg agttacaggc attgaatggt acattgacaa agacagaatg
    23041 gagttatcaa agtccggttg gaataataga agaatttaat caaatgaact attctatgaa
    23101 tttattgggt aacggcgcag cagttctgtt gattgtaatt ggattgatta actttatcaa
    23161 tgttatgttg acaggtgtgg ttgcaagaaa gaatgaattt gcagtcatgg aaagtattgg
    23221 aacttctaaa aaacagatta agaagatatt gaccttagag ggcggtattt acgcacttgt
    23281 aacgacaggt cttattatga cacttggcaa tgcgttctta cttcttgttg cagacgcagt
    23341 tccgcacata gcagactatg caaaatttga atatccattt gctcttgtaa tttgcttgat
    23401 atttgctata tttatcatat gtctaagtgt tccggcgatc gtatatcgtg cggtttcaaa
    23461 agaaacagtc attgaacgct tacatgactt aggaaattag tgttacacac agggcagata
    23521 tttctaacct ctgccctgtt attttgatat gaggtggtgg ttatatggca aatatatttt
    23581 tattagagga cgataagatt ttgagtaaag ggatttccat tgcattggaa aaagacggac
    23641 accatgttac aacggcatac ggttatgtag aagcattgca aaaatataca ttgaaaaagt
    23701 atgatctgtt tttgcttgat attaacctgc ccgatggaaa tggtatgaac ttctgccaaa
    23761 aaatcagaca gacctcacaa ttaccggtgt tatttttaac cgcaaatgat acagaggaag
    23821 atatgctaaa cggctatgat gtaggctgtg atgattatat ctccaaacca ttttctattg
    23881 atgttctgcg aagaaaagta tcggcaatac tgaaaaggac gattaccgaa acagcacaga
    23941 tacagtataa agatttggaa gtggatatag gaaaatgtct tgtgttatta aagggagaag
    24001 aagtccatct cagcgcaacg gaatataaat tgctttgtta tctgatacag cacaaaggaa
    24061 cggttgttac aaaagcaatg ctgctggaga atttatggga taaggacggc aactttattg
    24121 atgataatac tttgcgtgtg aacatcaaac gattaagaca aaaactaaaa gacgataacc
    24181 aagaatatat cgtaacagta ttcggaattg gttatacgtt cggagaataa acatgaagca
    24241 ttttaagtat atcagaaaaa ttcttatcat tttagaagtg atgatagcca ttgcacttgc
    24301 catagtccta tgttttatcc cgatggatat tttcgtaaaa gcaggattgc tggtgggagt
    24361 tgctatcttc tttctcatat tttatttgtt agaccatttg cacaaccgct atcttgatga
    24421 tatgttggaa gaactgacct ttttgattga agaattggtc ggcaagcagg aagtaaaagt
    24481 tttttcggaa ttagaggata ccttgctttc acgattgcag caccaacttt tgaagttgcg
    24541 ttctatcctg ataacacaaa atcaattatt ggatcgtgaa aagaaacaga ttaaagcgtt
    24601 gatttcggat atatcccatc agattaagac accggttgct tcagcgaaca cgttcgtaca
    24661 attattaaat gatgatacat tatcggaaga agaacgcaaa gaatatattg ctatcttaca
    24721 actatcactt gaaaaattaa cattcctagt caatagcctt gtgaagatgt cccgtttgga
    24781 aagtggcatt atttcattga aaccggagaa aaacagtctg aatgatatta tcttgcaggc
    24841 agtcaaatcg gtgtattcca aagcaaaagc aaaggatatt acgatcgtgt ttgattgtga
    24901 acaggactat atattatatt tggattttaa ctggacggca gaagccatca cgaatgtatt
    24961 ggataacgca gtgaaatata cgcaaaacgg tggaacggtt cgtctgaata tgaccgagta
    25021 tgcgtcttat cttcgcttgg atattataga caatggaatt ggcataccgg aagaagaaca
    25081 ggcgcagatt ttcaatcggt tttacagagg gaaatattct accggtgttg atggtgtcgg
    25141 aatcggttta tatctgacgc gcgatattat gacgaaacaa aagggatata tcaaagttat
    25201 ttcaaatgac acgggaacta cattctcttt gttttttcga ttgtatgtgg aagaataaca
    25261 gataagcagt tttatgaagt gctttaaggg ggcttgcatt atggaaagct ttaagaacag
    25321 ttctttacaa tcaaactcca cctaacagca ccctattaaa aattgaatat atttcggctt
    25381 ttatggctcg tacaaactat atgttttgtg cgggcttttt tcatgcccga aaaacttttt
    25441 taactttttt tcaaaaaaat catacaaatc acactttgcc ggacagtgtt atgcggaaag
    25501 agggagatac caacttttgc acaatgcaga aagggggtgt gatgatgaaa ccgacttctt
    25561 ttgaggacgc tattcgttta cagttcgata cattgatgaa gaaagtcatt gacaagacaa
    25621 ttaagaatta tgaacgcagt ttaacacgta gaaataaacg tgaagttctg ttctgtgaac
    25681 taccggagat tatggttcag tcctttcctg tctttgatga atatgattta gatgttgctg
    25741 attatgatgt ttacggtatg acagcgcatg tatgtgataa agaattatgc aacgcattag
    25801 atcagctatc agaaaaaagg cgaaatacca tattgttgtt ctattttctt gatatgtcag
    25861 atattgaaat aagcgaattg atgaatatta cacgttgtac ttcgtacacg cgtagaatga
    25921 ctgctttaag gcaaatgaaa gagattttag aaaaggggaa atgatttcat ggaaaaagat
    25981 gtttcaaagt gtccgcccta tcgcctgatt tcatcagcag cgaacggcga cgaaaaagca
    26041 attcagaaaa tcttagattt ctatgataac tacatatccg cttgttgtat gcggaaactg
    26101 tatgacgaat atggaaatgt tcgtatggca gtagatttag agttaaaagg acttgtgtgt
    26161 catgccatga tacagaagat aaaagccttt gaagtagaaa tcaagtagcg attatcaaca
    26221 gggtgtgatt taccacttct ctctttcccg ccctgtccat tcgtttatca ctctatgaaa
    26281 gtctgttgga aacaatagat tttcataggc tgacaagccg actgttcttt gaaaactgaa
    26341 taaagccgac aggcacgttt gctgtgcagt gagccatcag attttatacg ccatgacctt
    26401 tttattaaaa gtgagcgaaa tctatattga tctgggaaca gcctttggaa aagttgttca
    26461 gccacgacct gtgcagcagg ataatgatac gcccgcatgg tgcggttctg cccataagaa
    26521 tgggaatagt tgaaatacta gcggagcttt ccaaagccgt ctgtctgctt agaaaataca
    26581 tcacgaaaga aacttctaat atgttataat gagagtacaa tttttatact tgaaatatga
    26641 tgatgtggga gttggaagtg atgaaaatat tatatgttac cgatttgcat ggagataaag
    26701 agaagtacaa aaagacgtta gagattgcta tcgaaaaaca aattgatgtg attgtcaatg
    26761 gtggagatat gttgccaaag cagtgtaaca gacacttgga acagccagtc tttattaaac
    26821 aatttttaag ggaatacttc aaagagttgc agaaacataa catcaagtat cttgctatgc
    26881 ttggaaatga tgatttactg gctgttgatg atttgtttga tacagtttgt aatgaatttc
    26941 caaatgttta caatatagca ggaagaaaag tgaatattaa cggatttgaa tttattggta
    27001 tgaactatat tttagaccac cctttcggtt gtaaggatag agtgattaca gaaattgatt
    27061 atgtgccaca aagacagtta agcacttttg caggaacttc taatgaatat gactatgaca
    27121 gaatttataa ctggttggaa tattccaaaa cagaattacc ttatatgtgt gatgttctca
    27181 atcaattacc aaagccagac aatccgcaga aaactgtgta tatcatgcac atgccaccgg
    27241 caaggttgcg attgggacag ttgctttatc aggacttgga tataggttct gtcgatattt
    27301 acaattttct taaggaaagg cagccattgt tttctctgca tggacatata cacgaaagtc
    27361 cagataccga aaagggaaaa tggtgcaatc agataggtaa tacaatctgt attcaaacag
    27421 gccaaacaga actatttgcc agtgatatgg tatatgcaga aattgatttg caacatcagg
    27481 aatttaggcg tgaagtagtc aaagtgaaat aaacaagagg aacaccagag atggtgtttt
    27541 ttcttggctc gaaatgaggt gcagtaatgg aacaaaaagt aaaacaggat atgttgaaga
    27601 taaaagatac aacattttac attacttctg ttttctctgg aacagtagat ttacagtctt
    27661 tgataaaaag attgatacga agtgagattg aacagaaaaa cggtatgaat taaaaacagc
    27721 agaacaaacg gctgatatat gacggaaagc gtgttataat tgaatagtaa aaagatgttt
    27781 gtttgctgtt ggaaaggagc agaaatgtta aaacagcaga caagattaag agttagatta
    27841 tatgcacgtt tatcaaaaga tgatggagac gctgataagg aaagcaacag tattaaaaat
    27901 cagttgcaga tgttacgcta taatgcaaaa gagaaaggat ttatcgttgt cggcgagtat
    27961 gtagatgatg gttattcagg aacgacattc aatagacctg acctgaaccg tatgataaaa
    28021 gacgctatgg aagatacgga accgagtgga attatggtaa aggatatgtc aagatttggt
    28081 cgtaacaatg ccatgttcat gtattatgta gaagaaatct tcccgaacaa tgatattttg
    28141 tttattgcat tgaatgatga tgttgataca agatttgatg aaaacgaaat gatgcctttt
    28201 aagtcaatta tgaatgagta ttatgctcgc gatacatcaa agaaaattcg tagtgtcaag
    28261 aaaacaacag ccttgaatgg cggcttctgt ggttcatttg ctccatacgg atacagatta
    28321 gacccgcaga ataagcagaa gttactgatt gatgaagaaa cagcgcctat cgtcaagcgt
    28381 atttttgaat tatcaaaaca aggaaatggt attcatcaga ttgctagaat attgtgcgaa
    28441 gatggaattt taattccgag agcatacagg gcaatgaaaa acggtacttt agaaacaagt
    28501 acaggtttta agtttcctac ggactgggta gcaaaaaatg tgaaaatgat tttagaaaat
    28561 caagtatatc ttggacacat ggtttcgcat aaaacacaaa caaaatcatt taagaacaga
    28621 aaattggtgc ctgttccaaa agaagattgg attattgtta agaatacaca tgaacctatt
    28681 attgatgaag atacctttga attggtacag aagttcatta gtgtaaagaa acagccaaat
    28741 aaaactagaa agccgaatat gtttgtagga cttgtgaagt gtccggattg tgggcgcaat
    28801 atggcattga gtggccgtgc tgacagtagt agatggctac gttgtagaac ttatacaaga
    28861 aatacaaact tgtgtacttc gcattctata tcgtataatg ctttacagca gatagtaatg
    28921 aatgatattc aaaagcatat aaaaaatatg gaagccttag gcgatcagtt tctcgaagaa
    28981 atgaaagaat tgagtgaaaa aggtggaaat gaaaaaattc agcatttaaa acaaagttta
    29041 gaagttgctg aaaaaaggat tgaagaaata gacaatgtca ttatgaaatt gtttgaacag
    29101 aacgctttag gtaagatttc tgatgaacgt tttgaaaaga tgtctatatc atacgagaat
    29161 gaacaaagcg aattgaagtt gaaaagaaat gacttaaagg ataaaatcga gtcagaagaa
    29221 aagaaaaccc aaagtaccaa ccagttttta gaaactattc gtaagtatga aaatgtaaca
    29281 gaattaaatc gtgctatgtt ggtggaactg atagacagca tttatgtgta tcaggcagag
    29341 ggaacaggac aagaaaagac tcaaaaggtg gaaatcaatt acagatttct agcaggttct
    29401 caatgt
//
LOCUS       DAEORM030000045        29331 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.045, whole genome shotgun sequence.
ACCESSION   DAEORM030000045 DAEORM030000000
VERSION     DAEORM030000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 29331)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29331)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 29331)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29331
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.045"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            207..1358
                     /locus_tag="KRH23_002669"
     CDS             207..1358
                     /locus_tag="KRH23_002669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase family protein"
                     /protein_id="HHS5225947.1"
                     /translation="MEIYLDNSATTKPYQEVIDKMVYALNTEYGNPSSVHRKGVEVEK
                     AIKEVRQDIAKSLGAKEKEIYFTSGGTECNNTIIRGITSLNKKRKNHIISTNIEHPSV
                     LNTLKDLEEDGFEVTYLEVGKDGKINIEDLKNAIKSTTCLVSMMHVNNEIGTIQPIGE
                     VGKYLKGLKEKIYFHVDAIQSYGKINFRPSKYNIDFMSVSAHKFHGPKGIGFMYIKEN
                     NRLKPMLTGGGQEIGIRSGTENVPGIYGLGEAVRILNKDLDAVISKVNNLKNILKNEI
                     IDNIEDIKINSPEDGVCHILNVSFRGTKGEVLLHYLEQKGIYVSTGSACSSKKKGSYV
                     LNAIGLTNEEINGTIRFSLSDMNTEEEMLEAVKVLKESICDLRSIMKRK"
     gene            1404..2579
                     /gene="thiI"
                     /locus_tag="KRH23_002670"
     CDS             1404..2579
                     /gene="thiI"
                     /locus_tag="KRH23_002670"
                     /EC_number="2.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140741 - tRNA-uracil-4 sulfurtransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uracil 4-sulfurtransferase ThiI"
                     /protein_id="HHS5225948.1"
                     /translation="MVYNILIVKYGEIGVKGKNRYIFENRLIRNIRNMLKPIGRFNVY
                     KEYGRIYVDLEDYDYEEVIEEVRKVFGIVGVCPGVRAKKDYDTLKEIALKMLEEKIEA
                     GYKTFKVESRRGDKSFGLTSQEMSMDIGGYLLSKVGDRINVDVRNPEVKIKCEYREFH
                     TMVYSDTIPGYGGLPLGTNGRAMSLLSGGIDSPVATWMVAKRGMEVEAVHFHSYPFTS
                     ERSQEKVKDLAKILAKYCGRVRLHKVNILEIQKAIGENCNEEEATILSRRFMMRIAQR
                     LSEKRHCDALITGESIGQVASQTIQGLTCTNAVVDLPVFRPLIAMDKSDIVDIAKKIG
                     TFETSIVPEEDCCSVFSPRKPVTKPRLEKIEKSETALDIEKLIQDAIDKIEVEDIEF"
     gene            2715..3518
                     /locus_tag="KRH23_002671"
     CDS             2715..3518
                     /locus_tag="KRH23_002671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HHS5225949.1"
                     /translation="MNKKGFTLIELLVVISIIGILVIVAVPALFRNIEKSKAVTCLSN
                     RENIKTQIVIAMAEESSKDKNEVIKEVLENKDGKYFETEPKCKSGGIYSATFDDGYDG
                     ITGIESIAKVYVTCTKHPDGVEMARDVHQSMKDLIASFAQDPSIIPGASKGNDDFRKY
                     LLDNKYKNGWPTIPDEFKAKYGLSKDTLYIQPYAYNPTKSDATVVVFANNKTGGNWYT
                     SLVYDYDEGRWYKGKNGISVAGRSWDFDTDSVKSVKTEIHSKEGWGPLN"
     gene            3761..4402
                     /locus_tag="KRH23_002672"
     CDS             3761..4402
                     /locus_tag="KRH23_002672"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase"
                     /protein_id="HHS5225950.1"
                     /translation="MNNNFQDNQTINLIQSRRSIRKFTTEQISDEQVNTLLHCAFAAP
                     SGCNKQPWHITVVQDQKLLKEISDDTLSRIHEVSNVEINKNFKLFYGAPTVLFISYDE
                     SSSWAPYDIGILTGNITTAAQALGLGSCIIGMVRGLFTPVEQGDIEGLVSVLDKEDVK
                     ESESIKMKFDTNKKYRELLDIPEGYSVPFGIAVGIPDGNLPNAREVVYKVSRV"
     gene            5815..7485
                     /gene="pdcB"
                     /locus_tag="KRH23_002673"
     CDS             5815..7485
                     /gene="pdcB"
                     /locus_tag="KRH23_002673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphodiesterase PdcB"
                     /protein_id="HHS5225951.1"
                     /translation="MREESNSLSLDHIEIFFELLSQSTEDYIFFWDINRNKFKISSAI
                     FDEFNLSKEIESDLVNCWSKIVYPDDVQIWKDDIQELLHGKKGEHNLEYRLINKYKEI
                     VWISCRGKVYVSDDPKTIFLVGRIKNIGEKNKFDSITGTWNREQFEHRMNYLIKEKIY
                     KNGAMFIMDIDNFKNINEKYGHSYGDKVLRAIATEVLEYLPKDVRLYRLDGDEFAFFY
                     PMCTKETIEKIYEKIQMYTNTQHEIESNKYYCTVTAGVAMYPEDGDNYLDLFKHADIA
                     LDIAKISGKNRIKFFSQELYENKLKVISMQQKLRECVENNFNDFELFFQPQVNAVTKE
                     VIGAEVLLRWHSSTYGEVSPVEFIPILEQSNLIIPVGKWIIKEAVKQCKEWHKINPDF
                     KISVNVSYIQLKEDFFRDFIVECLVEYQLRPEFLILELTENCWIPDINLLNDKFISLK
                     GIGVYIAIDDFGTGYSSLNYLKELSVNIIKIERSFVKNITYNSYEYTFLEYIIKLAHI
                     INLKVCVEGIESYEEYDIVKSLGVDIIQGFLFGRPVSASEFYKFQLSK"
     gene            complement(7607..8341)
                     /gene="pflA"
                     /locus_tag="KRH23_002674"
     CDS             complement(7607..8341)
                     /gene="pflA"
                     /locus_tag="KRH23_002674"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043365 -
                     [formate-C-acetyltransferase]-activating enzyme activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate-lyase-activating protein"
                     /protein_id="HHS5225952.1"
                     /translation="MIKGKIHSIETFGTVDGPGIRYILFFQGCPLRCKYCHNRDTWDI
                     KSGKEYTVDEIITDALKYTSFMKFSGGGITASGGESTLQPEFLSELFKKAKENNIHTC
                     LDTSGFVDIETIDLVLDNTDLVLLDLKHMVEEKSIDLTGVGMDKALKLARHLESRNIP
                     VWIRHVLVPGITDDIDNLEKLGQFVATLKNVERFELLPYHSMGIHKWESLGIDYELKD
                     VPDATKEDVQKASEIISKFGVKVYNS"
     gene            complement(8495..10726)
                     /gene="pflB"
                     /locus_tag="KRH23_002675"
     CDS             complement(8495..10726)
                     /gene="pflB"
                     /locus_tag="KRH23_002675"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008861 - formate C-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HHS5225953.1"
                     /translation="MNAWQGFKTGRWTKEINVREFIQLNYSPYEGNDSFLAGATENTK
                     KLWDEAMVLFKKERENGGTLDVDTKTVSGIAAYAPGYLDKELETIVGLQTDAPLKRAV
                     MPYGGIKMVENSCEAFGYELDPEIKDIFTKYRKTHNQGVFDVYTPEMRAARKSGIITG
                     LPDAYGRGRIIGDYRRVALYGVDALIEDKNEQKKSLEVSCMDEEVIRLREEITEQISA
                     LNELKKMAESYGFDISKPATNSKEAVQWLYFGYLGAVKDQNGAAMSLGRTSTFLDIYF
                     ERDLKAGIVTEEELQEYMDHFVMKLRMVKFLRTPDYNNLFSGDPTWVTECIGGMGIDG
                     RTLVTKNSFRMLNTLYTLGPSPEPNLTVLWSTKLPQGFKDFCSKVSIDTSSVQYENDD
                     LMRAYWGDDYGIACCVSAMRIGKQMQFFGARVNLAKTLLYAINGGVDEKSGVQVGPRF
                     EPITSEYLDYDEVMSKFEPFTDWLATLYVNTLNVIHYMHDKYSYEALEMALHDRDIFR
                     TMACGMAGLSVCADSLSAIKHAKVKTIRNEQGIAVDFEIEGDYPKYGNNDDRVDSIAV
                     ELVESFMNKIRKNKTYRNSYPTQSILTITSNVVYGKKTGNTPDGRRAGAPFAPGANPM
                     HGRDTNGALASLSSVAKLPYEHAQDGISNTFSIVPAALGKDMTERINNLSAMMDGYFA
                     QNAHHLNVNVFDRATLEDAMEHPEEYPQLTIRVSGYAVNFIKLTKEQQLDVINRTFHG
                     KMA"
     gene            11085..12080
                     /locus_tag="KRH23_002676"
     CDS             11085..12080
                     /locus_tag="KRH23_002676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0098662 - inorganic cation transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="calcium/sodium antiporter"
                     /protein_id="HHS5225954.1"
                     /translation="MFITVVLFLVGFLLITKGADIFINCTVEIGKKTNISEIILGATI
                     VSFATTLPEFTVSLLASIDGHTTMSLGNAVGSIICNTGLALGLVVFISPFNVDKKMFF
                     SKSLLLIVSVIVLILLSLDGVITRGDSLLLIIILIFYMVNNYRSVVGKSDTKNRNIKN
                     NTIKDISTKKGKNYRGFSVLEIVKILLLFATGLIMMIIGSQILIESGVIIASFLNIPQ
                     GIVSLTIIALGTSLPEIVSSITAIRKNHHEISVGNILGANILNIVSVIAVSAIPNNIP
                     ILSQNRQLDIPFMILLLLIVIIPTLKSNKLSRIQGILMLFTYFLYISILYFMYII"
     gene            12171..13784
                     /locus_tag="KRH23_002677"
     CDS             12171..13784
                     /locus_tag="KRH23_002677"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HHS5225955.1"
                     /translation="MNITKFEDLPISEGIKKAIAEMGFEEPSPIQAQSIPAILSGKDV
                     IGQAQTGTGKTAAFSIPILETIDPNNRSLQAVVLCPTRELAIQVSTEIRKLAKYSHGI
                     KTLPIYGGQPIDRQIKSLKSGVQVVIGTPGRTIDHINRKTLKMDNVKMIILDEADEML
                     DMGFREDIEMILSKIPEERQTTFFSATMPRGILELTKRYQKDPEHIKVVRKELTVSNT
                     KQYYIETRSSNKLEVLCRLVDVYDPKLSVVFCNTKRKADELVGDLQARGYFADALHGD
                     LKQTQRDIVMDKFRNGTIDILVATDVAARGIDVDDVECVFNYDLPQDEEYYVHRIGRT
                     GRAGREGMSFTFVFGKEMRKMKDIERYTKSKLIKHNIPTITDVEEKKVGTFFAQVKQT
                     IEEGHLTKQLQWLEGFCNDEDYAMVDIAAALVKLSLGEEMKEEIIEEKPRRERGDRKG
                     GTGAKDGMIRLFINIGRNQRVQAKDIVGAIAGEVGIPGKVVGTIDIYDKYTFVEIPKK
                     DAKTVIEKMKDIKIKGNKINIEKANKKKK"
     gene            14115..16427
                     /locus_tag="KRH23_002678"
     CDS             14115..16427
                     /locus_tag="KRH23_002678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HHS5225956.1"
                     /translation="MDIIKKLSHGCTLDCHDCCKFNVYTKGNNVVKIEGDKNHPYTKG
                     FICKKGMAHLDRLNHKDRIKTPMLKVDGVWKEISFDKAIEIMAEKLTYYKEKYTSKSV
                     MHYDQYGSGSVLKYIGDIFFNFYGGVSRHKGGPCWSAGMHAQKYDFGVAKSHAIEDML
                     NSKSIFVWGKNPAYTTIHTMQIIKKAKEKGIKIVVIDPIYTKTAQIADKYVQVNPGTD
                     GALAIAMAKIIVEDKLYDEEYINSYVIGFEEYKKYLSSLELSFLIDECGVKENDIREL
                     VDLYTNKYSSINVGYGLQKYKNGGNTIRAIDALGAITGQIGFSGGGVNYANKVYPSVI
                     NSDPYNSQSYGEDREFYVSNISKFIEESLKNTSNKVNYASDELDTTSNKVNYISDELD
                     TTSNKVNYILDELDTTSNKVNCVSDELDMTSNKVNYVSDELDMTSNKVNYVLDELDIT
                     SNKTDYISNELYNLSNKSIKDNIPIKMAVITKSNMLNQLPDLVELERVFSKIEFKVCF
                     DMFITDTATLCDMFIPCTNTLESEDIIYSSMTNPYITYNERAVNPAHKLMDEYYFFME
                     LAKKMGLNDYPFVEKRTYLEKVIEPLKRFDKNLDIEKLKNNYFTIHNPVAWEDKKFET
                     PSGKYELYSESIKNLGISPTPVYISNKYKEIEDKNISFRLLTNHHADTLFSQHFMDKK
                     SIAQAYINRRMAKKVGIEDKDIVILRSKKAKINVQINIDDGVGNYIVKMYVGWWKKHG
                     NPNSLTDTGISDFGGQVTYNESMVEIIRQN"
     gene            16515..16850
                     /gene="spoIIAA"
                     /locus_tag="KRH23_002679"
     CDS             16515..16850
                     /gene="spoIIAA"
                     /locus_tag="KRH23_002679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0045152 - antisigma factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0030435 - sporulation resulting in
                     formation of a cellular spore [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anti-sigma F factor antagonist"
                     /protein_id="HHS5225957.1"
                     /translation="MVNYSLEHKNLYIEFMCSELDHHVANEIREEIDNLLSVNQVKNV
                     VFNFENINFMDSSGIGVIIGRYKKISNEGGRVSVINISSRVKKIFDLSGLNKIIGIYD
                     TYEEALSSL"
     gene            16864..17292
                     /gene="spoIIAB"
                     /locus_tag="KRH23_002680"
     CDS             16864..17292
                     /gene="spoIIAB"
                     /locus_tag="KRH23_002680"
                     /EC_number="2.7.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004672 - protein kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016989 - sigma factor antagonist activity
                     [Evidence IEA];
                     GO_process: GO:0006468 - protein phosphorylation [Evidence
                     IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA];
                     GO_process: GO:0042174 - negative regulation of
                     sporulation resulting in formation of a cellular spore
                     [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anti-sigma F factor"
                     /protein_id="HHS5225958.1"
                     /translation="MNNIMEVKFSAISENESLARVIVASFAAKLDPTVDELVDIKTAV
                     SEAVTNAIIHGYEEDSSKFVFLRCEIEGNTIKIIVEDEGYGIENVEKAMEPLYTSKPE
                     LDRSGMGFTVMKSFMDDVEVSSVKDNGTRIEMTKKINVPK"
     gene            17315..18079
                     /gene="sigF"
                     /locus_tag="KRH23_002681"
     CDS             17315..18079
                     /gene="sigF"
                     /locus_tag="KRH23_002681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sporulation sigma factor SigF"
                     /protein_id="HHS5225959.1"
                     /translation="MEVTVAREEKKPLLSHEETLELIEKVQNGDEEAKEILISSNLGL
                     VRSVVSRFLNIGYDREDLFQLGSIGLIKSIYKFDPKFNVKFSTYAVPMILGEIKRYLR
                     DDGMIKVSRSLKQIAVKAKMESEALTKKLGREPSIEELAKAIDVEKEDLVMAMEANFN
                     VEYLQGVIHEEEGSPICLIDKISMKGESEEEKVVDNILLKDILGRLDKRERQIIVLRY
                     FEDMTQSEIGEMLNISQVQVSRIEKKVLSKLKEYIS"
     gene            18359..18796
                     /gene="spoVAC"
                     /locus_tag="KRH23_002682"
     CDS             18359..18796
                     /gene="spoVAC"
                     /locus_tag="KRH23_002682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein AC"
                     /protein_id="HHS5225960.1"
                     /translation="MDKNYKKYVDQISPKPTYLKNYTLAFIVGGIICMIGQAINDLYM
                     KVGGLDKLGASSATSITLIFIGAFLTGLGVYDLIGKRAGAGSIIPITGFANSIVSPAM
                     EYKREGYVLGVGANLFKIAGPVLVYGIGSSILCGIIYYIFKMF"
     gene            18963..19976
                     /gene="spoVAD"
                     /locus_tag="KRH23_002683"
     CDS             18963..19976
                     /gene="spoVAD"
                     /locus_tag="KRH23_002683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein AD"
                     /protein_id="HHS5225961.1"
                     /translation="MKNKRIGKRTVKLENKPTIISTGTIVGPKEGEGPLKDYFDMIMT
                     DDLYGEKTWELAESKMVETASQQAIQKAGKKLSDVNYMLGGDLINQIVPASFAARELA
                     IPFLGIYGACSTMAEGLCIGSMLIDGGFADLVLSGTSSHYCTAERQFRFPLELGNQKP
                     MTAQWTVTGAGSVLLAPNGDGPKVKYVTVGKVIDEGIDDGNNMGPAMAPAAIDTIYSY
                     FEDTNDDPNSFDIIATGDLGTLGKQIAEDFLKEKGVDISKVYTDCGIEMFNLKEQDVH
                     CGGSGCGCSATVFAGYIYDKLRKKEFNKVMLVSTGALLSPTSTLQKQTIPCVAHAVVI
                     VNE"
     gene            19990..20352
                     /gene="spoVAE"
                     /locus_tag="KRH23_002684"
     CDS             19990..20352
                     /gene="spoVAE"
                     /locus_tag="KRH23_002684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein AE"
                     /protein_id="HHS5225962.1"
                     /translation="MLMDYVRVFIVGGIICLIAQVMMDYFKMQTPYVMVTYVTTGVVL
                     TFLGLYEPLVKFAAAGATVPIIGFGYSLATGVIKSIQSDGFLGIFLGGTTATAGGIAA
                     AIFFGYIMSVVFTPKAKP"
     gene            20535..21551
                     /locus_tag="KRH23_002685"
     CDS             20535..21551
                     /locus_tag="KRH23_002685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HHS5225963.1"
                     /translation="MVTIKDIARNLGISYSTVSRCLNNNPNVSEKTKKKVVEEANRLG
                     FHFNVNARNLAKKETNRIGVIFSNNFNHQDTRKFFSDIMDSSINSIETNKYDFIIQPN
                     NNISGDSNVYKMVNGQMVDGLVIVSQSIKKEEYDFLKDNNFPHVFIYFKPSFIGEVDN
                     FFWDDNVYGGYIATKHLIDHGHKDIITVTSDDKSSKMHEDRTKGYLNAMEEANLKTEV
                     IKSKMDFESQVEFLEKYIDKIKKASAIFVQQDVPAISIIQELKTTYGINVPEDISIIG
                     YNNIELISYFRSHLSTIDDPREQVIKNGVDSLVNIINKKSTEHIPRKLYPRLIIRNSV
                     KRIK"
     gene            21926..22768
                     /locus_tag="KRH23_002686"
     CDS             21926..22768
                     /locus_tag="KRH23_002686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3100 domain-containing protein"
                     /protein_id="HHS5225964.1"
                     /translation="MKEKAGIRNAIIAAFIITILAELIGPISFKVMGINVTLLSILWA
                     IFIGMAVSPHLLGRVIPALKKFIGDNEINVSPYLLSLTLYPLGIMFGINAGPKVGILL
                     QAGPALLLQEFGHMGTMLIALPVGVALGLGRSALGGTFSLCRDTALGIIGDKYGLNSP
                     EGIGTLGTYISGSIFGTLLFSFLAPVGVLLGFHPYALAMASGMGSGSMMGAATASLMN
                     TVPQMSEQILAYSATSGLITAVTGIYIELFLSLPVANYYYSKVAPVIERFRGRKTRRT
                     SNKL"
     gene            22783..23247
                     /locus_tag="KRH23_002687"
     CDS             22783..23247
                     /locus_tag="KRH23_002687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5225965.1"
                     /translation="MEKTFKTIMEQIKIVLFIYIIICFGQMIALKTQAQDLLIGSVSG
                     FLLVIIAIIIKNFVKKPNLPGFAWATLVAFVLSLPISPVGDIIATNVGKINFMSTVTP
                     LLAFAGISVGNQLDILKTLSWKLVVISFIVMTSTYFGSAFISQTVLRLNGML"
     gene            23261..24406
                     /locus_tag="KRH23_002688"
     CDS             23261..24406
                     /locus_tag="KRH23_002688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HHS5225966.1"
                     /translation="MNELKAKIKEEIKLLSEEKKTSFEKVSDYLFSNPELAFEEYKSQ
                     KALCDLLEENEFNVTKGVGGLETSFEAVYSNGTNGKTVAFLAEYDALPGMGHACGHNI
                     IGTSSVGAGIILKEIMKKHNIEGTVKVFGTPAEERVGGKITMIKEGVFNNVDAALILH
                     PSDASMPDDISFAQVNLKFDFTGKASHAAAFPWEGKSALSGVIALFNSVNSMRLHLKD
                     YARVHGIITDGGSIHNIIPEKSTAIFNVRALSIEYLNEICEMLKNCAKGAAISTGTNV
                     EIVQLDEIYKEIKNDSELVNIVRQNFEVLGEDYVERDLSQGIGSTDTGNLTHEIPAIQ
                     AYIKLKENTATHTDEFAVAAGGEEGRVALIKAIKVLAMCGVDILYSK"
     gene            24450..25385
                     /locus_tag="KRH23_002689"
     CDS             24450..25385
                     /locus_tag="KRH23_002689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1177 domain-containing protein"
                     /protein_id="HHS5225967.1"
                     /translation="MILKQVIEVYDILDKANANGEEVKTYLQGYGEVDVTVKELSSSK
                     GSTDLVKLTIPGKNGKLKGGDAPTLGILGRLGGIGARPEVIGFVSDGDGALVAIAVAA
                     KLLDMQRKGDILDGDVVISTHICPDAPTKEHYPTPFMDSPIDMMTMNENEVDSSCDAI
                     LSIDTTKGNRVINTRGFAISPTVKEGYILKTSDNLLDIMQTVTGKSPFVFPLSIQDIT
                     PYGNNLYHLNSILQPAVATDAPIVGVAITTEMPVAGCATGATNFSDLDSAGRFAIEVA
                     KLFGRNKCDFYDKEEWEMLIKRYGKLNRFQTFGIQ"
     gene            complement(25659..28352)
                     /locus_tag="KRH23_002690"
     CDS             complement(25659..28352)
                     /locus_tag="KRH23_002690"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008955 - peptidoglycan
                     glycosyltransferase activity [Evidence IEA];
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase domain-containing protein"
                     /protein_id="HHS5225968.1"
                     /translation="MNNDNDKNGNKIRRKKVSSSGNTNKPINRTSANKTRSTKNKKKS
                     KKSDKFKKLRVFGIVFLVLLVVGTAGTAGLVFASLRDVTPVTEAVLDKQTNQTTTIKY
                     ANGKTLSTAPSVNKKTPVPLDKISPYLQHAVIAIEDERFYEHKGVDIKGLFRSVLKTL
                     TGTKQGGSTIPMQVSKMLLTTEQQTIPRKIKDIYYAHEMSKTVSKDKILETYLNNFFV
                     GRGLAGAEAGARGYFDKSAADLTLAESALLAGSTKNPSRFSAYKTSKLEGNETKEDLE
                     NKLLFFVNTTDDDLDDPTQVDFDMIEKIKSWELISNDTYRQLKAGTLVVRKAVSNPEA
                     KKRQEIVLKKMLELKYIKQSEYDEAIKAKIEIKLPQSSDKVSSSVEDLIESEVINALM
                     EQGHTNDEAQNLFYNGGLIVNTTIDPKMQDALEEEFDRNSNFPGHMVGPDGVSQPQAA
                     MVILDYKNGEIRALAGGRNISGRKTLNRATNPHQPGSSIKPLAIYTPAIDTLKITQAT
                     ALSDSRGGYKFEENNKWNPRTTTAGHGSMSLRKALAKSSNTIAVKTAEMLGDSYDECV
                     DIMMDYLKNFGITTLKNNHSGSSEASDRKFPSLTLGGMANGITPLQMAAAYGTLANQG
                     VYVEPSIFTTITTFDGQLLVKNAPEEHKVVDPEVAYVVTDMLESVITEGIGGVATLPK
                     GMPVAGKTGTTNSAYDAWFVGYTPYYVGATYIGDDAGRKDDSGNTIKRREVPHGSTST
                     AKLWEKIMEKIHANLTVTEFEVPKNVYFTKINLEDGGKQSSGSKAAFIEGTAPTKVSS
                     QPSSEDTKKPDNNQPEENNNNNNNTGDNGGGSTPPDNGGNNGGGSTTPPDNGGNNGGG
                     STTPPDNGGNNGGGSTTPPDNGGNNGGGSTTPPDGGGTPAT"
     gene            28566..29264
                     /gene="yunB"
                     /locus_tag="KRH23_002691"
     CDS             28566..29264
                     /gene="yunB"
                     /locus_tag="KRH23_002691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein YunB"
                     /protein_id="HHS5225969.1"
                     /translation="MNRIVDRKTKNEFRKIIAIFLVILFLSVFIGSFIYIDKTLRPTI
                     TVLAETKALELANRSINKAVAEMVEGKINYEDLMDIQLDNNGKITMIQANTIMMNEIA
                     SAIALEIQDELKKDKTASSYIPIGTALGSPILAKYGPKLEVSIEPIGTVSVNFKTEFE
                     SSGINQTRHRIYLEAQTQVKVVIPLITSTKQIKAQIPICETIIVGDVPESYVNIPEKN
                     LGNVLPNTGKNTNK"
BASE COUNT        11144 a         3487 c         5042 g         9658 t
ORIGIN      
        1 tttataatat atttttgtag ggtatagtat aagtatatta tattttacta taaaaatttg
       61 taataaagtg aaaaaactag cttttcatga aataatattt tataatttaa gattgtcttt
      121 ttaataaaga ttaacaaaaa aaatactata attagtggta taatagttag agttgaagat
      181 tttaaataaa ggtaggtgta attaagttgg aaatatactt agacaatagc gcaactacaa
      241 aaccttatca agaagttata gataaaatgg tttatgcact taatacggaa tatggaaatc
      301 cttcttctgt ccatagaaaa ggtgtagaag ttgaaaaagc tataaaagaa gtaagacaag
      361 atatagctaa atctctagga gcgaaagaaa aggagattta ttttacatca ggtggtacag
      421 agtgtaataa tactataata agaggtatta ctagtttaaa taaaaaaaga aaaaatcaca
      481 taatatctac taacatagaa catccttctg ttttaaatac attaaaagat ttagaagaag
      541 atggttttga agtaacttat ttagaggtcg gaaaagatgg gaaaataaat atagaggatt
      601 taaaaaatgc gataaagtca actacatgct tagtaagcat gatgcatgtt aacaatgaaa
      661 taggaactat acagccaata ggtgaagttg gaaagtattt gaagggttta aaagaaaaaa
      721 tttatttcca tgttgatgct attcagtcat atggaaaaat taactttaga ccatctaaat
      781 acaatataga ttttatgagt gtaagtgcac ataaatttca tggtccaaag ggaattggat
      841 ttatgtatat aaaagaaaat aatcgcctta agcctatgtt aacaggtggt ggtcaggaaa
      901 ttggaattag gtcgggaaca gaaaatgtac ctggaatata tggtcttgga gaagctgtta
      961 gaatactaaa caaagattta gatgctgtta tttcgaaagt aaataactta aaaaatatat
     1021 taaaaaatga aataattgat aatatagaag atataaaaat taattctcca gaagatggag
     1081 tatgtcatat attaaatgta tcatttagag ggacaaaagg agaagtttta cttcattact
     1141 tagagcaaaa aggtatttat gtatcaactg gctctgcatg ttcttctaaa aagaaaggta
     1201 gttacgtatt aaatgctata ggtcttacaa atgaagaaat aaatggaaca ataagattta
     1261 gtttatctga tatgaataca gaagaagaaa tgttagaagc tgtgaaagtt ttgaaagaat
     1321 caatttgtga cttaaggtca ataatgaaaa gaaaataaag aatactgtat agatagtgat
     1381 aataaattag tttaagaggt gaaatggtgt ataatatatt aatagtaaag tatggagaaa
     1441 ttggagtaaa aggaaagaat agatatatat ttgagaatag gcttataaga aatataagaa
     1501 atatgttaaa accaattgga agatttaatg tatataaaga gtatggaaga atatatgttg
     1561 atttagaaga ctatgattat gaagaagtaa ttgaagaagt tagaaaagta tttgggatag
     1621 tgggtgtgtg ccctggagta agagctaaaa aagattatga tacattaaaa gaaatagctt
     1681 taaaaatgtt agaagaaaaa atagaggctg gatataaaac ttttaaggta gagtcaagaa
     1741 gaggagataa gtctttcggg ttgacttctc aagaaatgag tatggatata ggtggatact
     1801 tattatcaaa ggtaggagat aggattaatg ttgatgtaag aaatccagaa gttaaaataa
     1861 agtgcgaata cagagaattt catactatgg tctatagtga tactatacct ggatatggtg
     1921 gattgccact tggaacgaat ggtagagcta tgtctctttt atcaggaggt atagatagtc
     1981 cagtagctac atggatggtt gcaaaaagag gtatggaagt agaggcagtt cactttcata
     2041 gttatccatt tacaagtgaa aggtcacagg aaaaagttaa ggatttagct aaaatactgg
     2101 caaaatactg tggtagagta agacttcata aagttaacat attagaaata caaaaagcaa
     2161 ttggtgagaa ttgtaatgaa gaagaagcta ctattctttc aagaagattt atgatgagga
     2221 tagcgcagag gctttctgaa aaaagacatt gtgatgcttt aattacaggt gaaagtattg
     2281 ggcaggttgc atctcaaact atacaagggc ttacttgtac taatgccgtt gtagacttac
     2341 cagtgtttag accacttata gcaatggata aatcagatat agttgatata gccaaaaaaa
     2401 tagggacttt tgaaacatct atagtgcctg aagaagattg ttgtagtgta ttttctccta
     2461 gaaagcccgt cactaaacct agattagaga aaatagaaaa atctgaaaca gcacttgaca
     2521 ttgaaaaatt aatacaggat gctattgaca aaatagaggt agaggatatt gagttttagc
     2581 atacgagtta tttaattatt gaattgaata ttgagtatat tagtagttct gttgaaagga
     2641 tttatgtaga caatttatta atatgtagta tttaaaaata agtactataa ttttatttaa
     2701 tgggaatgat tattatgaat aaaaagggtt ttacattaat tgaattgttg gtagttatat
     2761 ctataatagg aattttagtt atagtagctg ttccagcgtt atttagaaat atagaaaaaa
     2821 gtaaagcagt tacatgtctt tctaatagag aaaatataaa gactcaaatt gttattgcaa
     2881 tggctgagga atcaagtaaa gacaagaatg aagtcataaa agaggtatta gaaaacaaag
     2941 atggtaagta ctttgaaaca gaaccaaagt gtaagtcagg tggaatatat tcagcaacgt
     3001 ttgatgatgg ttatgatgga ataactggaa tagaaagcat tgcaaaagtg tatgttactt
     3061 gtacaaaaca tccagacggt gttgaaatgg ctagggatgt gcatcaaagt atgaaagatt
     3121 tgattgcatc atttgcacaa gacccttcta taataccagg agcttcaaag ggcaatgatg
     3181 attttagaaa atatttatta gacaataaat ataaaaatgg gtggcctaca attccagatg
     3241 aatttaaggc aaaatatgga ttaagtaagg atacactata tatacaacca tatgcatata
     3301 atcctactaa atctgatgct actgtagttg tatttgcaaa taataagact gggggtaatt
     3361 ggtatacttc cctagtttac gattatgatg aaggtagatg gtataaaggt aaaaatggta
     3421 tttctgttgc aggtaggtca tgggattttg acacagatag tgttaagtct gtaaaaacag
     3481 agattcattc taaagaggga tggggtcctt taaattaata tatcatgttt tattaatctg
     3541 gtattgatta aactatagaa aagagcagtt tctatagatg acgaatacca gattttcatt
     3601 tatatatata attgagacat attaaaagtg tttatatttt taagtcttca catacaagct
     3661 aaaaataatt ataataatat tgtaaagaaa tttaattata agattaattt tctgaagatt
     3721 tagtatttgt actaagaaat acataaaaag gggaatagat atgaataata attttcaaga
     3781 caaccaaaca ataaatttaa tacaaagtcg tagaagtata cgaaaattta cgacagaaca
     3841 aattagtgat gagcaagtaa acacattatt acactgtgca tttgcagcac cttcaggatg
     3901 taataaacag ccttggcaca taactgttgt gcaagaccag aaacttttaa aagagattag
     3961 tgatgatact ttatctagga ttcatgaagt gagtaatgtt gagataaata aaaactttaa
     4021 gttattttat ggtgctccaa ccgttttatt tatttcttat gatgaaagta gttcatgggc
     4081 tccatatgat ataggaatac ttacagggaa tataacaaca gctgcacaag cactagggct
     4141 tggaagttgt ataataggaa tggttagagg tttatttaca cctgttgaac aaggggatat
     4201 tgaaggtctt gtgagtgtat tggataaaga agatgtaaaa gaatcagagt caataaagat
     4261 gaagtttgat acaaataaaa aatacagaga actacttgat ataccagaag ggtattctgt
     4321 accatttggt attgctgtag gtattccaga tggaaattta ccaaatgcta gagaggtagt
     4381 ttacaaagtt tccagagttt aggataaagt attgcaagaa ccaatcagtt acttgaagaa
     4441 ttaaaccagt aatatacaaa taaattgatg gaagaggaag ctatttaaaa agtagtttag
     4501 attttttgtt gtaaaataat taaataaaga ataaggtgat aagtatttta tttattatct
     4561 tattcttttt tatttttgtt ttgtagaatg ataaaaataa ggattaagtg taataaaata
     4621 gaaaacaagt atgttaattt taagtatatg ctttaaaatt tatccaagtt aaaaatttaa
     4681 gatatctttt cagtataatg gaaaaaatgt caaaatattg aaatagggaa aaaatagtga
     4741 tataataaga aaaaatagag aaaaaaagta acccttagtt ataaaaaagt tactatttat
     4801 tgaaaattta gatatttttc taaaaactat ctatgttaat agttaaattt atgaacattt
     4861 tttgttttta tgttaggata tttcttagaa atgaaatact tcttaatttg atttgatatg
     4921 tatattttta tagctatttt attataaaaa aaaagaaccc ttttataaca aatggaaact
     4981 atggatgtaa taattaaaat aaaaaatatt attttatatt tataaacatt gacattctaa
     5041 ttttgtagtg taatcgtatt ttttattaat tcttacaaaa tcaatgaaaa taagtatatc
     5101 cattttaaag tacataaatt taaaaatcca gaaaaatata cttaaattat gtaagtaaaa
     5161 gaggggttga atcagttgaa aatgtaatat tagtaaatag tacatcaatc ctatataccc
     5221 tgtaagcaac tctattttca tgtactaaaa atgtacctat tttattaact gaaaagaata
     5281 aattaaatgt aagtacataa gaagatagaa aaaattaaaa acaaaaaata tttatataaa
     5341 taaatataaa aaatgatata atccctatta aaaaatttat agatgatgaa gaaatatcaa
     5401 aatcttatat tataggaaga gacacttctt tgccaaaatc tatagaaaag caataccaaa
     5461 tccaaagaga ataggcgaag aaaaaaataa aataaattca agagtaatag aaaagtttta
     5521 tagaataaag aactgataac tctttatata acgaaaaata gaattttaag agaaaatgat
     5581 ttaataaatg atttaacatg gtgttttagc aggtaaaaat aaatcaccag taatgattat
     5641 agaaaaatta ctttatgaat ctcaaaaaac ttagttaaga gtaagagatt tgataagata
     5701 actaaagttg gggaaatgtg tttgatgaga taaaaaatta gtaaaatagt ataatctaaa
     5761 taaggatatt ttgttgatta aactacacta atagtaatat tgtaggggga aaagatgaga
     5821 gaagaatcga actctttaag tttagaccat atagaaattt tctttgaact tttatctcaa
     5881 agtacagaag attatatatt tttttgggat ataaatagga ataaatttaa aatttcttca
     5941 gcaatttttg atgaatttaa cttaagtaaa gagatagaat ctgatttggt caattgttgg
     6001 agtaaaattg tttatccgga tgatgttcaa atatggaaag atgatataca agaattacta
     6061 catggaaaaa aaggtgagca caatttagaa tataggttga ttaataaata taaagaaata
     6121 gtatggattt cttgtagagg taaagtttat gtgtcggatg acccaaaaac tatatttcta
     6181 gtcgggagaa taaagaatat tggtgaaaaa aataaatttg attctatcac aggaacgtgg
     6241 aatagagaac aatttgaaca tagaatgaat tatcttataa aagagaaaat ttataaaaat
     6301 ggtgctatgt ttattatgga tattgataat tttaaaaata taaatgaaaa atatggacat
     6361 tcttatggtg acaaagtatt gcgtgcaatt gctactgaag tattagaata tcttccaaaa
     6421 gatgtaagat tgtataggtt agatggagat gaatttgcat ttttttaccc tatgtgtact
     6481 aaagaaacta tagagaaaat atatgaaaag atacagatgt atacaaatac tcagcatgaa
     6541 attgaatcaa ataagtacta ttgcacagtg actgcaggcg ttgctatgta tccagaagat
     6601 ggagataatt atttagattt atttaaacat gctgatattg cattggatat agcaaaaatt
     6661 agtggtaaaa atagaattaa gtttttttca caagagctct atgaaaataa actaaaggta
     6721 atttcaatgc aacaaaaact aagagagtgc gttgaaaata attttaatga ttttgagttg
     6781 ttttttcaac cccaggtaaa tgctgttaca aaagaggtaa taggggcaga ggtactttta
     6841 agatggcatt cgagtactta tggagaagta tctcctgttg aatttatacc aatactagaa
     6901 cagagtaatt taattatacc agttgggaag tggattataa aagaagctgt aaaacagtgt
     6961 aaagaatggc ataaaataaa tccagacttt aaaatatctg taaatgtatc gtatattcag
     7021 ttaaaggaag atttttttag agattttata gtagaatgtt tagtagagta tcaattaaga
     7081 cctgaatttt taattttgga attaacagag aattgttgga taccagatat aaatttacta
     7141 aatgataaat ttattagttt aaagggtata ggagtatata ttgcaataga tgactttggt
     7201 acaggatatt catctttaaa ttaccttaaa gaactgtctg ttaatataat aaaaattgaa
     7261 agaagttttg ttaagaatat tacatataat agttatgaat atacttttct tgaatatatt
     7321 attaaattag ctcatattat aaatttaaaa gtttgtgttg agggaataga gtcttatgaa
     7381 gagtatgata tagtaaaaag cttaggggta gatattattc agggtttttt atttggaaga
     7441 cctgtaagtg cctctgaatt ttataaattt cagctatcaa agtgatgtat ataaaatgag
     7501 atatatagta tataaaaata gggcaaagtg gaagttttga agtttattaa aaatttacac
     7561 tttaccctat tttgttatgt cttctataaa ggattaatat actacactaa ctattatata
     7621 ctttcactcc aaatttagag attatttcac tagctttttg gacatcttcc ttagtggcat
     7681 caggaacatc ttttagttca taatcgatac ctaaactttc ccatttgtgt attcccatag
     7741 aatggtatgg aagcaattca aatctttcta catttttcaa tgtagctaca aattgaccta
     7801 gtttttctaa attatctata tcatcagtaa tgccaggaac taaaacatgt cttatccata
     7861 caggaatatt tcttgattct aagtgtctag caagttttaa tgccttatcc ataccaacac
     7921 cagtcaaatc aatagatttt tcctcaacca tatgttttaa atcaagtaaa accaaatcag
     7981 tattatctaa aactaggtct atagtttcta tatctacaaa tccagatgta tccaagcaag
     8041 tgtgtatatt attttctttt gcttttttaa ataattcact taaaaattct ggttgaagag
     8101 tggattcacc accagaggca gttatacctc caccagaaaa cttcataaaa gaagtatact
     8161 taagagcatc cgttattatt tcatcaactg tgtattcttt tcctgattta atatcccatg
     8221 tatccctgtt atgacagtat ttgcatctaa gaggacaccc ctgaaaaaat aatatatatc
     8281 ttattcctgg tccatctaca gtaccaaacg tttctataga atgtatcttt cccttaatca
     8341 tagagttcac ctcacaatat attttaataa ccttatcaat agttataata tttctctaaa
     8401 aaaggccatc ttataccaga aataattcaa atataagata gccttttatt ttttacacag
     8461 tagtaatctt agttaaagta taaaaattta aagactaagc cattttaccg tggaatgttc
     8521 tgtttataac atctaattgt tgctctttag ttaattttat gaagttaact gcatatccag
     8581 atactcttat agttaattgt ggatattctt ctggatgttc catagcatct tctaaagtag
     8641 ctctatcaaa tacatttaca tttaagtgat gagcattttg agcgaagtat ccatccatca
     8701 ttgcagaaag attgtttatt ctttcagtca tatcttttcc taaagcagca ggtactatag
     8761 agaaagtatt agatatacca tcttgagcat gttcatatgg taatttagca actgaagata
     8821 atgaagctaa agcaccatta gtatctctac catgcattgg gttagcacca ggagcaaatg
     8881 gagcaccagc tcttctacca tctggtgtat taccagtttt cttaccataa acaacatttg
     8941 aagttattgt aagtatagat tgagtaggat aagaatttct ataagtttta ttctttctta
     9001 ttttattcat aaagctttca actaactcta cagctatact atcaactcta tcatcattat
     9061 ttccgtattt tggataatct ccttctattt caaaatcaac agctattcct tgttcatttc
     9121 taatagtttt aaccttagca tgttttatag cagataatga gtctgcacaa actgataatc
     9181 cagccatacc acaagccata gttctaaata tatctctatc atgtaatgcc atttctaatg
     9241 cttcataaga atatttatca tgcatataat gtattacatt taaagtattt acatataatg
     9301 ttgctaacca atcagtgaat ggttcaaatt tactcataac ttcatcataa tctaagtact
     9361 cagaagttat aggttcaaat cttggtccaa cttgaacacc agatttctca tctacaccac
     9421 catttatagc gtataataaa gttttagcta agttaactct agctccaaag aactgcattt
     9481 gtttaccaat tctcattgca gatacacaac aagctatacc atagtcatct ccccagtatg
     9541 ctctcattaa atcatcattt tcatactgta ctgaacttgt atctatagat actttagaac
     9601 agaaatcttt gaatccttga ggtaatttag ttgaccatag aactgttaag tttggttctg
     9661 gagaaggtcc taatgtatat agagtattta acattctaaa tgagttttta gtaactaatg
     9721 ttctaccatc tattcccata cctcctatac actcagttac ccaagttggg tctccagaga
     9781 ataggttatt gtaatcagga gttcttagga acttgaccat tcttaatttc ataacaaaat
     9841 ggtccatata ctcttgtaat tcttcttctg ttacgattcc agcttttaaa tctctttcaa
     9901 agtatatatc taagaaagta gatgttctac ctaaagacat tgcagcacca ttttggtctt
     9961 taacagcacc taaataacca aagtataacc attgtacagc ttcttttgag ttagttgctg
    10021 gttttgatat atcaaatcca taagattcag ccattttttt aagttcattt aaagctgata
    10081 tttgctcagt tatttcttct cttaatctga taacttcctc atccatgcaa gaaacttcta
    10141 atgatttctt ttgctcattt ttatcttcta ttaaagcatc aacaccgtat agagcaactc
    10201 ttctgtagtc accaattatt ctacctctac cataagcatc tggaagacct gttattatac
    10261 cagattttct agcagctctc atttctggag tataaacatc aaaaactcct tggttgtgtg
    10321 tttttctgta tttagtaaat atatctttta tttctgggtc taattcatat ccaaaagctt
    10381 cacatgaatt ttcaaccatc tttataccac catatggcat gacagctctt tttaaagggg
    10441 catccgtttg taacccaact attgtttcta attctttatc taaatatcct ggagcatatg
    10501 cagctattcc agaaacagtt tttgtatcaa catctaaagt accaccattt tctctttctt
    10561 ttttaaatag gaccattgct tcgtcccata attttttagt attttcagtg gcaccagcta
    10621 agaaagagtc atttccctca tatggagaat agtttaattg tataaactct ctaacattta
    10681 tttctttagt ccatcttcct gttttaaatc cttgccatgc attcattaag tatttcctcc
    10741 ttagatttaa atgataaata atactattaa aattaatttt tatatactta atttatttta
    10801 tatatttttt taaaaatata ttttctaata taataatagc atattattcg tatcctgtat
    10861 acataaaaaa taaaaaattg tcgctttaaa gtataaaaca gattatatgt taataatgtg
    10921 gtgaaattat acccatatat aaataaaata aaacaaataa atagctaatt aaggagaaaa
    10981 tattttttat tttttgttta ggataaataa attttattat ggaaaaaaga aaaagcatac
    11041 atcttcacaa actgaatatt tatttaatag ggggaggtga tagattgttt atcacagtgg
    11101 tattattttt agtaggtttc ctattaatta ctaaaggcgc agatatcttt ataaattgta
    11161 ctgtagagat aggtaaaaaa acgaatatat cagaaattat acttggagct actatagtta
    11221 gttttgcaac aacattacct gaatttacag tgtctctact tgcttctatt gatggtcata
    11281 ctactatgag tttaggaaat gcagttggtt ctataatatg taatacaggg ttagcattag
    11341 ggttggttgt ttttataagt ccatttaatg tagataaaaa aatgtttttt tctaagtctt
    11401 tactattaat agtatccgtt atagttttaa ttttattgag tttagatgga gttataacaa
    11461 gaggtgattc attattactt ataataatat taatctttta tatggttaat aattatagaa
    11521 gtgtcgttgg aaaatctgat actaaaaata gaaatattaa aaataacact attaaagaca
    11581 tatctactaa aaaagggaaa aattataggg gtttttccgt attagaaatt gtaaaaatac
    11641 tattactttt tgctacagga ttgataatga tgataatagg ttcacaaatc cttatagaga
    11701 gtggagtaat aatagctagt tttttaaata tacctcaggg tatagtaagt ttaactataa
    11761 tagcacttgg aacttctctt ccagagatag tttcgtcgat tactgctata agaaaaaatc
    11821 atcatgaaat atcagtagga aatattttgg gtgcaaacat attgaatata gtatcagtaa
    11881 tagctgtatc agcaatacca aataacatac caatactatc tcaaaataga caattggata
    11941 taccattcat gatattatta ttattaatag taataatacc aacacttaaa tctaataaac
    12001 ttagtagaat acaaggtata ttgatgttat tcacatattt tctgtacata tcaattttgt
    12061 atttcatgta tattatttaa ctatactgtt taaaatatta attgcagaat atcctaaaaa
    12121 agtatataat ggataggtta agattaattg ataacggaga ggaataatat atgaatataa
    12181 caaagtttga agatttacca ataagtgagg gaataaaaaa agctatagct gaaatggggt
    12241 ttgaagaacc atctcctata caagcacagt ctatacctgc gattttgtca ggtaaagacg
    12301 ttataggaca agctcaaact ggtacgggaa aaacagctgc ttttagtatc cctatactag
    12361 aaacaataga cccaaataat agaagtttac aagctgtagt gctttgtcca acaagagaac
    12421 tggcaataca agtatcaaca gaaataagaa agttagctaa gtattcgcac ggaataaaga
    12481 cattacctat atatggtggt cagccaatag atagacaaat aaaatctcta aagagtggtg
    12541 tgcaagttgt aataggtaca ccaggacgta caatagacca tatcaatcgt aaaacattaa
    12601 agatggataa tgtaaaaatg attatattag atgaagcaga tgaaatgcta gatatgggat
    12661 ttagagaaga tatagaaatg attttaagta agattccaga agaaagacaa acaactttct
    12721 tttcagctac tatgccaaga ggaattttgg aattaactaa gagatatcaa aaagacccag
    12781 agcatataaa agttgttaga aaagaactta cagtttcaaa tacaaagcaa tactatatag
    12841 aaactaggtc atcaaataaa ttagaagtat tatgtagatt agtagatgta tatgacccta
    12901 aactatctgt tgttttctgt aatactaaga gaaaagcaga tgaattggta ggagatttac
    12961 aagcaagagg atattttgca gatgcattac atggtgactt aaaacagact caaagagata
    13021 tagtaatgga taagtttaga aatggtacaa tagatatact tgttgctact gatgttgcag
    13081 ctagaggtat agatgttgat gatgttgaat gtgtattcaa ctatgactta ccacaagatg
    13141 aagagtatta cgttcataga attggtagaa ctggtcgtgc tggtagagaa ggtatgtcat
    13201 ttacttttgt atttggaaaa gaaatgagaa agatgaaaga tatagaaaga tatactaaat
    13261 ctaaactaat aaagcataat ataccaacaa taactgatgt tgaagagaaa aaagtaggta
    13321 ctttctttgc acaagttaaa caaactatag aagaaggtca cttaactaaa caattacaat
    13381 ggttagaagg tttctgtaat gatgaagatt atgcaatggt tgatatagct gctgcacttg
    13441 taaaactatc tctaggtgaa gaaatgaaag aagaaataat agaagaaaaa cctagaagag
    13501 agcgtggaga tagaaaaggt ggtactggag ctaaagatgg tatgattaga ttatttatca
    13561 atattggtag aaatcaaaga gtacaagcaa aagatatagt tggtgctata gctggagaag
    13621 ttggaatacc aggtaaagta gtaggtacta tagatatata tgataagtat acttttgttg
    13681 aaatacctaa aaaagatgca aaaacagtaa ttgaaaagat gaaagatatt aagataaaag
    13741 gtaataagat taatatagaa aaagcaaata agaagaaaaa ataacgtata gtatacaaaa
    13801 ctataattag aaaatatata aaataatata ttggatattt aaaaagcctg atgtgttttc
    13861 aaaacagata gtagataatc tgtaagagtt aacagcataa ggcttttctt gttttatata
    13921 aggaatctga ataacttact gttaaatctt tgaattactg cacctcattt atgttaagga
    13981 tggagtattc tacctatttt tgataaaata tatctatgtt ttatatactg tagttttgaa
    14041 tatataaagt ttaataaatt atagtatata tgttaatttt taataaggta agaaagtaga
    14101 aagaaggata ttttatggat ataataaaaa aattaagtca tgggtgtaca ttagattgtc
    14161 atgactgttg taaattcaat gtttatacta aaggaaataa tgtagtaaaa attgaaggag
    14221 ataaaaatca tccttataca aaaggtttta tatgcaaaaa agggatggcc catttagata
    14281 gattaaatca taaagataga ataaagactc ctatgcttaa agttgatgga gtatggaaag
    14341 agatttcttt tgataaagct atagaaataa tggcagaaaa gcttacatac tataaagaaa
    14401 agtatacatc aaagtctgtc atgcattatg accaatatgg aagtgggtct gtgctaaaat
    14461 acataggaga tatatttttt aatttttatg gaggtgttag cagacataag ggtggtccct
    14521 gttggagtgc agggatgcat gctcaaaaat atgattttgg agtagctaag agtcatgcta
    14581 tagaagatat gttaaatagt aaaagtatat ttgtgtgggg aaaaaatcca gcatatacta
    14641 caattcatac tatgcaaata attaaaaaag ctaaagaaaa agggataaag atagtagtga
    14701 ttgacccaat atatacaaaa acagctcaaa tagcagataa gtatgtacaa gtaaatcctg
    14761 gaacagatgg agctttagct atagctatgg caaaaattat agtagaagat aaattatatg
    14821 atgaagaata tataaactcg tatgttattg gttttgaaga atataaaaaa tatttatctt
    14881 cattggaatt aagtttttta attgatgaat gtggtgttaa agagaatgat ataagagagt
    14941 tagtggattt atatactaac aaatattcaa gtataaacgt tggatatggg cttcaaaaat
    15001 ataaaaatgg tggaaacaca ataagagcaa tagatgcttt aggtgctata actggtcaaa
    15061 taggatttag tggtggaggg gtaaactatg ctaataaagt ttatccgagt gttataaatt
    15121 ctgaccctta caatagccaa tcatatggtg aagataggga gttttatgta agtaatatca
    15181 gtaaatttat agaagaatct ttaaaaaata catcaaataa agtaaattat gcatcagatg
    15241 aacttgatac aacatcaaat aaagtaaatt acatatcaga tgaacttgat acaacatcaa
    15301 ataaagtaaa ttacatatta gatgaacttg atacaacatc aaataaagta aattgtgtat
    15361 cagatgaact tgatatgaca tcaaataaag taaattatgt atcagatgaa cttgatatga
    15421 catcaaataa agtaaattat gtattagatg aacttgatat aacatcaaat aaaacagatt
    15481 atatatcaaa tgaattgtat aatttatcta ataagtcaat caaagataat attcctataa
    15541 agatggctgt gataactaaa agtaatatgc tgaatcaact gccagattta gtagaattgg
    15601 agagggtgtt ttcaaaaatt gaatttaaag tatgttttga tatgtttata actgatacag
    15661 ctactttatg tgacatgttt ataccgtgta caaatacact agagagtgaa gatataattt
    15721 atagctcaat gaccaatcca tatataacct ataatgaaag agctgtaaat ccagcacata
    15781 aattgatgga tgaatattac ttctttatgg agctagctaa aaagatggga ttaaatgatt
    15841 atccttttgt agaaaagaga acttatttag aaaaagtgat tgaaccactt aagcgttttg
    15901 acaaaaatct ggatatagaa aaacttaaaa acaattactt tactatacat aaccctgttg
    15961 cttgggaaga taagaagttt gagactccat ctggaaaata cgagctttat tcagaaagta
    16021 taaaaaactt gggaataagt ccaacacctg tatatataag caataaatat aaagaaatag
    16081 aagataaaaa tatttctttt agattattaa ctaatcatca tgcagatact ttatttagtc
    16141 agcattttat ggacaaaaaa tctatagctc aagcatatat aaatcggaga atggctaaaa
    16201 aagtaggtat tgaggacaaa gatattgtga tattgaggtc aaaaaaagca aaaataaatg
    16261 tacaaataaa tatagatgat ggagtaggta attatatagt aaaaatgtat gttggttggt
    16321 ggaagaaaca tggaaatcct aatagtttaa cagacactgg tatatcagat tttgggggtc
    16381 aggtaacata taatgaaagt atggtagaaa taatacgaca aaactagtta aatttcattg
    16441 aaggaataaa aatataatta tagaattgat taaaagttac tatttttaca aaactattga
    16501 aggagggatt tttgatggta aattattcct tagaacataa gaatctatac atagaattta
    16561 tgtgctcaga actagaccac catgtagcca atgaaataag ggaagaaata gataacttat
    16621 taagtgtaaa tcaagtaaaa aatgttgtat ttaattttga aaatattaat tttatggatt
    16681 cttcaggtat aggcgtcatc ataggtagat ataaaaagat ttctaatgaa gggggacgag
    16741 tttcagtaat taatataagt tcacgagtta agaagatttt tgatttatct gggttaaata
    16801 aaattattgg catttatgat acgtatgaag aagctctaag ttctttgtag ggaggagtat
    16861 gtgatgaata atattatgga agttaaattt tcggcaatat ctgaaaatga aagtttagca
    16921 agagttatag tagcatcctt tgcagctaag ttagacccaa cagtagatga gttagtagat
    16981 ataaaaactg ctgtctctga ggctgttacg aatgctataa tacatggata tgaagaagac
    17041 agttctaagt ttgttttctt aagatgtgag atagaaggaa atactataaa gattatagtt
    17101 gaagatgaag ggtatggaat agaaaatgtg gagaaggcaa tggaaccact ttatacatca
    17161 aaaccagaac ttgatagatc aggaatggga ttcacagtaa tgaaaagctt tatggacgat
    17221 gtagaggtaa gttctgtaaa agataatggg actagaattg aaatgactaa aaaaataaat
    17281 gtgcctaaat aaagtccaaa agtgaggttt tattatggaa gtaactgttg ccagagaaga
    17341 aaaaaaacct cttcttagtc atgaagagac tctagaactt attgaaaaag ttcaaaatgg
    17401 agatgaagag gcaaaagaaa tattaatatc aagcaattta ggtctagtta ggagcgttgt
    17461 atctagattt ttaaatatag gatatgatag agaagattta tttcagttag gttctatagg
    17521 cttaataaaa tcaatatata aatttgaccc aaaatttaat gtaaaattct ctacttatgc
    17581 agtaccaatg attttaggtg aaataaagag atacttaaga gatgatggta tgataaaagt
    17641 atcaaggtcg ttaaagcaaa tagctgtaaa ggcaaagatg gaaagtgaag ctttaactaa
    17701 aaaattaggt agagaaccga gtatagaaga attagctaaa gcaatagatg tagaaaaaga
    17761 agatttagta atggctatgg aagctaattt caatgttgag tatttgcaag gagttattca
    17821 tgaagaggaa ggttctccaa tatgccttat tgataaaata agcatgaaag gagaaagtga
    17881 agaagaaaaa gtagtggata acatattgtt aaaagacata cttggaagac tggataagag
    17941 agagcgtcaa ataatagttc tcagatactt tgaagacatg actcaaagtg aaataggaga
    18001 gatgctcaat atatcacaag ttcaagtatc taggatagag aagaaagtat tgtctaagtt
    18061 aaaagaatat atatcgtgat aatacttatg atatgtagaa taacaaaata taataaatat
    18121 attactaaaa taaaatgtaa taacttttta tgttaagttt ttaaattatt aaaagatatt
    18181 aaaataataa aaagcattaa aaaagtaaaa atataaaaac aaggtgtctt tatggaaaaa
    18241 tagatttttt ctttattaga catctttttt attttttgac caaactttag atagtcaaaa
    18301 taaataatag gtttattttt ttaaaattaa caaataatac tttagagagg tgtttagtat
    18361 ggataaaaat tataaaaaat atgtagacca aataagccca aaacctacat atttaaaaaa
    18421 ctatacactt gcatttattg taggtggaat tatttgtatg atagggcaag caataaatga
    18481 tttgtatatg aaagttggag gtcttgataa actaggtgct agttctgcaa catcaataac
    18541 attaatattt ataggggcat ttttaactgg attaggagtt tacgacctaa taggaaaaag
    18601 agctggagct ggttctataa ttccaataac aggttttgct aactcaatag tatctccagc
    18661 aatggagtat aaaagagaag gctatgtatt aggtgtaggt gcaaacttat ttaaaattgc
    18721 aggaccagtt ttagtttatg gtataggttc ttctatttta tgtggaatta tttattatat
    18781 ttttaagatg ttttagatga tttttattta atttaaattt tattaattat gaagaaggta
    18841 taaaatctga aaatagctac taaagtaact aattgaaaaa taattgtgca gatttaatta
    18901 atatttttaa ttaatattaa aaatttgaat agtaaaatgc aaaattaaaa aggtgtgaaa
    18961 atatgaaaaa taaaagaatt ggaaaaagaa cagtcaagtt agaaaataaa ccaaccataa
    19021 tatcaactgg aactatagta ggtcctaagg aaggtgaagg accactaaag gactattttg
    19081 atatgattat gactgacgat ttatatggtg aaaagacttg ggaattagct gaaagtaaaa
    19141 tggtagagac tgcatctcaa caagctatcc aaaaggcagg taaaaaattg tcagatgtaa
    19201 attatatgct aggtggcgat ttaataaatc aaatagttcc agcatcattt gcagcaagag
    19261 aactggctat tccattttta ggtatatatg gagcttgttc tacaatggca gaaggtcttt
    19321 gtataggttc tatgcttata gatggtggtt ttgctgattt agtactgtca ggtacatcaa
    19381 gtcactattg tacagcagaa agacaattta gattcccact tgaacttgga aatcaaaagc
    19441 caatgacagc tcagtggaca gttacaggag cgggaagtgt attattagct cctaatggag
    19501 acggtccaaa agtaaagtat gttactgttg gtaaagtaat agatgagggt attgatgatg
    19561 gtaataatat gggaccagct atggctccag cagcaataga tactatctac tcttactttg
    19621 aagatactaa tgatgaccca aatagctttg atataattgc tactggagat ttaggtactc
    19681 ttggcaaaca gatagcagaa gactttctaa aagaaaaagg tgtagatata tcaaaagttt
    19741 acactgactg tggtatagag atgtttaacc ttaaagaaca agatgtccac tgtggtggaa
    19801 gtggatgtgg gtgttcagct acagtgtttg caggatatat atatgataag ttgagaaaaa
    19861 aagaatttaa caaagtaatg cttgtatcaa caggagcact actttcacca acaagtacac
    19921 tacaaaagca gacaatacca tgtgttgcac atgcagtagt aatagtaaat gagtaggaag
    19981 tgatataata tgttaatgga ctatgtaaga gtatttattg taggtggaat tatatgttta
    20041 atagcccaag taatgatgga ttatttcaaa atgcaaactc catatgttat ggtaacgtat
    20101 gtaacaactg gtgtagtttt aacttttcta ggactttatg agccattagt taagtttgca
    20161 gcagcaggtg caacagttcc tataatagga tttggatatt cacttgctac aggagtaata
    20221 aaatcaattc aaagtgatgg ttttttaggt atttttttag gaggtacaac tgctacagct
    20281 ggtggaatag cagcagctat attctttgga tatattatgt cagtagtatt tactccaaaa
    20341 gcaaaaccat aaatctttat taaaagaata ataagttttt gaaataataa ctttttataa
    20401 agcaggtgga tatcttttag attccaccta ttttttatat aaagaagcgt ttacataatt
    20461 gaagttgaca attatttaca acatagtgta gtattatatt atcaaaataa aatgaagtga
    20521 agtaggggat aaagatggta actattaaag atattgcaag gaatctaggt atcagttatt
    20581 caactgtttc taggtgctta aacaataatc ctaatgtatc tgaaaaaaca aaaaagaaag
    20641 tggtagaaga ggcaaataga ctagggttcc attttaatgt aaatgcaaga aatttagcaa
    20701 aaaaagaaac taacaggata ggggtaatct tttcaaataa ttttaatcat caagatacta
    20761 gaaagttttt tagtgatata atggatagtt ctataaattc tattgagact aataaatacg
    20821 attttataat acagcctaat aataacatta gtggtgatag taatgtatat aaaatggtaa
    20881 atggacaaat ggttgacgga ttagtaattg tgtctcaatc aataaaaaaa gaagagtatg
    20941 attttttaaa agacaataat tttccacatg tatttatata ttttaaacca tcttttatag
    21001 gagaagtaga caatttcttt tgggacgata acgtgtatgg aggttatata gctaccaagc
    21061 atttaattga ccatggtcat aaagatataa taacagtaac ttcagatgat aagagttcaa
    21121 aaatgcatga agatagaacc aagggatatt tgaatgctat ggaagaagca aatttaaaga
    21181 cagaagtcat taaatctaaa atggattttg aatctcaagt tgaattttta gaaaaataca
    21241 ttgataaaat aaaaaaagct tcagctatat ttgtacaaca agatgtacca gcgatttcta
    21301 taatacaaga gttaaaaact acttatggta taaatgtacc agaagatatt tccataatag
    21361 ggtataataa tattgaatta atatcatatt ttaggtcgca tttatcaaca atagatgacc
    21421 caagagagca agttataaaa aatggagtag atagtttagt aaatataata aataaaaaga
    21481 gtacagaaca cattccaaga aaattatatc caaggttaat aatacgaaat agcgttaaaa
    21541 gaataaagta gtaagctttt aagtatcaaa agtttattaa aaatattata gattatgtga
    21601 agttttttaa caaataatat aaataaaaat taaaaggagt aggtgtatat aagtacattg
    21661 tactccttta tttattgaga tagtttttat aatatgaatg aataatttta ttcaattatt
    21721 tgaaaatccg ttattttaac aatataaatt aataaattat ttgtatttta tatcatgaat
    21781 ctataatatt tttttgattc ataactaaaa gtatataaaa atgatgaata aatatatatt
    21841 atacattatc aatgataggt tatataataa aatcactaac aattatatta taagaaaatt
    21901 ataaaaatta caaggaggta tagaaatgaa agaaaaagca gggattagaa atgccataat
    21961 agcagccttt ataatcacaa tattggcaga attaattgga cctatttcat ttaaagttat
    22021 gggaattaat gtaactttac ttagtatact atgggctata ttcataggaa tggctgtttc
    22081 tcctcattta ttagggagag ttataccagc cctaaaaaag tttatagggg ataatgaaat
    22141 aaatgtatct ccatatttat tatctttgac actatatcca ttagggataa tgtttggaat
    22201 taatgcaggg cctaaagttg gtatattact tcaagcagga ccagcacttt tattacaaga
    22261 atttggtcat atgggtacaa tgttgatagc attacctgtt ggagtagcat taggtcttgg
    22321 aagaagtgca ttaggtggta ctttttcatt atgtcgtgac acagcactag gaattattgg
    22381 agataagtat ggattaaact caccagaagg tataggaaca ctaggaactt acataagtgg
    22441 tagtatattt ggaacattat tattttcatt tttagcacca gtgggtgtac ttttaggatt
    22501 tcatccatat gctttagcaa tggcatcagg aatgggtagt ggttcaatga tgggagctgc
    22561 aacagcatca ttaatgaata cggttccaca aatgtcagag cagattttag catattcagc
    22621 tactagtgga ttgattacag ctgttactgg aatatatata gaattattct tatctttacc
    22681 agtagccaac tactattata gcaaagtagc tccagttatt gaaagattta gaggaagaaa
    22741 aacaagaaga acaagtaata aattgtaaag gaggatatat atatggaaaa aacttttaag
    22801 actattatgg agcagataaa aatagtattg tttatatata ttattatttg ctttggacaa
    22861 atgatagcac ttaagactca ggctcaagat ttgttgattg gaagtgtatc tggatttttg
    22921 ttggtgataa ttgctattat aataaagaat tttgttaaaa aacctaattt accaggtttt
    22981 gcatgggcta cattagttgc attcgtttta tcgcttccaa tatctccagt gggggatatc
    23041 atagcaacaa atgtagggaa aatcaatttt atgtctacag taacaccatt attagctttt
    23101 gcaggaatct ctgtaggtaa ccaattagat atattaaaga ctttgagttg gaagttagta
    23161 gttatatcat ttatagttat gacatctact tactttggtt ctgcttttat atctcaaaca
    23221 gttttaagat taaatggaat gctttaagga ggtagtaaat atgaatgaat taaaagcaaa
    23281 aattaaagag gaaataaagt tattatctga agagaaaaag acatcatttg aaaaagtttc
    23341 tgactattta ttttcaaatc cagaattagc atttgaggag tataagtcac aaaaagcatt
    23401 atgtgatttg ttagaagaaa atgaatttaa tgtaactaaa ggtgtaggag gattagaaac
    23461 atcttttgaa gctgtgtatt caaatggaac taatgggaaa acagttgctt ttttagctga
    23521 atatgatgca cttccaggaa tgggacatgc atgtgggcac aatatcatag ggacaagttc
    23581 tgttggtgca ggtatcatat taaaagaaat catgaaaaaa cataatatag aagggactgt
    23641 aaaggttttt ggaacacctg cagaagaaag agtaggtgga aaaataacta tgattaaaga
    23701 aggtgtattt aataatgtag atgctgcatt aattttacat ccaagtgatg cttcaatgcc
    23761 tgatgatata tcatttgctc aagttaattt aaaatttgat tttactggta aggcatcaca
    23821 tgctgctgct tttccttggg aagggaaaag tgccttaagt ggagtaatag cactatttaa
    23881 cagtgtaaat agcatgagat tacatcttaa agattatgca agagtacatg gaattataac
    23941 tgatggaggt agcatacata atataattcc tgaaaaatct acagctatat ttaatgtaag
    24001 agctttaagt atagaatatt taaatgagat ttgtgaaatg cttaaaaatt gtgctaaagg
    24061 agctgcaatt tctactggaa ctaatgtaga aatagttcaa ttagatgaaa tatacaaaga
    24121 gattaagaat gattctgaat tagtgaatat agttagacaa aattttgaag ttttgggtga
    24181 agactatgtt gaaagagatt taagtcaagg tataggttca actgatacag gaaatttaac
    24241 tcatgagata cctgcaatac aagcatatat aaaattaaaa gaaaatactg caactcatac
    24301 agatgaattt gctgttgcag ctggtggtga agaaggcaga gtagcactta taaaagcaat
    24361 taaggtgcta gcaatgtgtg gagtagatat tttgtatagt aaataatata taattttaaa
    24421 atatattaag aaaggaaatc agattagaca tgatattaaa acaagtaata gaggtttatg
    24481 acattttaga taaagcaaat gctaatgggg aagaagtaaa aacttactta caaggttatg
    24541 gtgaagtaga tgtaactgta aaagaattgt cttcaagtaa aggctcaaca gatttagtaa
    24601 agcttacaat tcctgggaaa aatggaaaat taaaaggtgg agatgctcct actcttggta
    24661 ttttaggtag actaggaggg attggagcaa gaccagaagt tataggtttt gtttcagatg
    24721 gtgatggagc attggtagca attgcagtgg ctgctaaact tttggatatg caacgaaaag
    24781 gggatatatt agatggtgat gttgtaattt caacccatat ttgcccagat gctccaacta
    24841 aagaacacta tcctactcct tttatggatt ctccaattga tatgatgact atgaatgaaa
    24901 atgaagttga tagtagttgt gacgcaatac tttctataga tactactaaa ggaaatagag
    24961 taatcaatac tagaggattt gcaatatcgc caactgttaa agaaggctac atattaaaaa
    25021 ctagtgataa ccttttagat attatgcaga ctgtaacagg gaaatctcca tttgtattcc
    25081 ctttgtctat tcaagatata acaccatatg gaaataatct gtatcactta aatagtattt
    25141 tacaaccagc agtagctaca gatgcaccaa tagtaggagt agcaattaca acagagatgc
    25201 ctgttgctgg atgtgctaca ggtgcaacta attttagtga tttagattca gctgggagat
    25261 ttgcaattga agttgccaag ctatttggta gaaataagtg tgatttctat gataaagaag
    25321 agtgggaaat gcttattaag agatatggca aattaaatag atttcaaaca tttggtatac
    25381 agtaattaga aaaatattaa gtttatataa tttgtgatat aactatttaa gaatatataa
    25441 acaattagga ataaaagtaa gaataaagca cttagttaaa aactttaaaa ataaaatatt
    25501 tatttgttta tataaaaagg aggattctgg ttattgggat tctctttttt atgaatacaa
    25561 ataatatatt gtaattataa aaaaaggagc gtttcaaagt gattttttta atcaccttga
    25621 gacaactcct tatattttta tttaaattct attttttatt aagttgctgg agttccacca
    25681 ccatcaggag gagtagtaga gccaccacca ttatttccac cattatcagg aggagtagta
    25741 gagccaccac cattgtttcc gccattatca ggaggagtag tagagccacc accattattt
    25801 ccgccattat caggaggagt agtagagcca ccaccattgt ttccgccatt atcaggaggt
    25861 gtagaaccgc caccattatc acctgtgtta ttattgttat tattattttc ttctggttgg
    25921 ttattgtctg gtttttttgt atcttcagat gatggttgag aacttacttt agtaggagca
    25981 gtaccttcaa taaatgctgc tttagagcca gaagattgct ttcctccatc ctctaaatta
    26041 atttttgtaa aatatacatt tttaggaact tcaaattcag taaccgttaa attagcatgt
    26101 attttttcca taattttttc ccatagtttt gcagtactag tacttccatg tggtacttct
    26161 ctacgtttta tagtgttacc agaatcatct tttctaccag catcatctcc aatataagtt
    26221 gcaccaacat aataaggagt gtaaccgaca aaccaagcat catatgcact atttgtagta
    26281 cctgttttac ctgctacagg cattcccttt ggaagtgtag caacaccacc aataccttca
    26341 gtaattacgc tttctaacat atctgtaacg acataagcta cttcagggtc tacaacttta
    26401 tgttcttcag gagcattttt aactaataat tgaccatcaa aggtagttat agtagtaaaa
    26461 atagaaggtt ctacataaac accttgattt gccaatgtac cataagcagc agccatttga
    26521 agtggagtaa taccattcgc cataccacct agtgtcaatg atgggaattt tctatcactt
    26581 gcttcagatg aacctgagtg attattcttt aaagttgtta taccaaagtt ctttaagtaa
    26641 tccatcatta tatctacaca ttcatcataa gagtctccaa gcatttcagc agttttgaca
    26701 gctatcgtgt ttgaagattt agcaagtgct ttacgtaaac tcatagaacc atgaccagca
    26761 gtagtagttc ttggattcca tttattattt tcttcaaact tatatcctcc tctagaatca
    26821 cttagagcag ttgcttgtgt tatttttaga gtatcaatag ctggcgtata tattgctaaa
    26881 ggttttatag aagaacctgg ctgatgaggg ttagtagcac gatttaaagt ttttctacca
    26941 cttatatttc ttcctccagc tagtgctctt atttcaccat ttttataatc taagattacc
    27001 attgcagctt gcggttggct aactccatca ggaccaacca tatgtcctgg gaaattgcta
    27061 tttctatcaa attcttcttc taaagcatct tgcattttag ggtctatagt tgtgtttaca
    27121 attagaccac cattgtagaa taagttttga gcttcatcat ttgtatgtcc ttgttccatt
    27181 aaagcattta taacttcact ttcgataagg tcttctacag atgaagaaac tttatctgat
    27241 gattgaggca attttatttc tattttagct ttgattgctt catcatattc actttgtttt
    27301 atatatttca attctaacat tttctttaaa acaatttctt gtcttttttt agcttcagga
    27361 ttacttacag cctttctaac aactaatgta cctgctttta attgtctata agtatcatta
    27421 gatataagct cccaagattt tattttttca atcatatcaa agtccacttg agtagggtca
    27481 tctaaatcat catcagttgt gttaacaaaa aataataatt tattctctaa atcctcctta
    27541 gtttcatttc cctctaactt agaagtttta taggctgaaa atcttgatgg atttttagtt
    27601 gaaccagcaa gaagtgctga ctctgctaga gtaaggtcag ctgcagactt atcaaaataa
    27661 ccacgtgcac cagcctcagc acctgctaga cctctaccaa cgaagaagtt atttaaataa
    27721 gtttctagta ttttatcttt acttactgtt ttactcatct catgtgcata gtaaatatcc
    27781 tttattttac gaggtatagt ttgctgttca gttgttaaca gcattttgga tacctgcata
    27841 ggaatagtac taccaccttg cttagtacct gtaagtgtct ttaatactga cctaaataaa
    27901 cctttaatat cgacaccctt atgctcataa aaacgctcat cttctattgc aattacagca
    27961 tgttgaagat aaggggaaat cttatctaat ggaacgggtg tctttttatt tacacttgga
    28021 gctgtagata atgtttttcc attagcgtat ttaatagtag ttgtttggtt cgtctgttta
    28081 tctaaaacag cttctgtaac tggagttaca tctcttagtg acgcaaatac tagaccagca
    28141 gtacctgctg taccaacaac tagtaaaact aaaaatacta tcccaaatac tcttagtttt
    28201 ttaaatttat cgcttttttt agattttttc ttgttttttg ttgaacgagt cttgttagct
    28261 gaagttctat taattggttt atttgtatta ccagatgagc taactttttt tctcctgatt
    28321 ttatttccat ttttatcatt atcgttattc ataagatttt aacctcctta cttaatgcaa
    28381 tattataaca caaataggag tagttttgta attaatagaa aaaatgaatt tgctataata
    28441 ttctgtacat tgtatatgta taaacgtaat atattaaaaa gtctatattt ttattttatt
    28501 tatttttgac aaatattata aaaattatgc caaagctaca tataaataaa taggagggga
    28561 taattttgaa tagaatagta gatagaaaaa caaaaaatga atttagaaaa atcatagcta
    28621 tttttttagt aattcttttc ttgtctgtat ttataggcag ttttatatat atagataaaa
    28681 ctttaagacc gacaataaca gttttagcag agactaaagc tcttgaacta gcaaataggt
    28741 cgataaataa agctgttgct gagatggtag aaggaaaaat aaattatgaa gatttaatgg
    28801 atatacaact tgataataat ggtaaaataa ctatgataca agcaaacact ataatgatga
    28861 atgaaattgc atctgcaata gctttagaaa tacaagatga attaaaaaag gataagacag
    28921 caagttctta catacctata ggaacagcat taggaagtcc tatattagct aaatacggtc
    28981 ctaaacttga agtatctatt gaacctatag gaacagtatc agtaaacttt aaaacggaat
    29041 ttgagtcttc aggtataaat caaactagac atagaatata tttagaagct caaacacaag
    29101 ttaaagtagt aataccactt ataacttcaa caaaacaaat taaagctcaa atacctattt
    29161 gtgaaactat aatagtaggt gatgttccag aaagttatgt aaatattcca gaaaaaaatc
    29221 taggaaatgt tttacctaac actggaaaga ataccaacaa gtaatataaa gttgtatatt
    29281 tttaaataaa ttcaaaataa tagtttataa ataaaatttt tggaaataat a
//
LOCUS       DAEORM030000046        28373 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.046, whole genome shotgun sequence.
ACCESSION   DAEORM030000046 DAEORM030000000
VERSION     DAEORM030000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 28373)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28373)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 28373)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28373
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.046"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            <1..420
                     /locus_tag="KRH23_002692"
     CDS             <1..420
                     /locus_tag="KRH23_002692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferritin-like domain-containing protein"
                     /protein_id="HHS5225970.1"
                     /translation="DEHRIGVAQGVDAEIIEGLRANFTGECTEVGMYLAMSRQADREG
                     YPEVAEAYKRIAFEEAEHAAKFAELLGEVVVADTKENLRVRVDAEYGATDGKLKLAKR
                     AKELGLDAIHDTVHEMCKDEARHGKAFLGLLNRHFGK"
     gene            520..1668
                     /locus_tag="KRH23_002693"
     CDS             520..1668
                     /locus_tag="KRH23_002693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF362 domain-containing protein"
                     /protein_id="HHS5225971.1"
                     /translation="MKSVSVRSCKTYNYEEVKLSIEKNLEDIGGIDKFVKKGSKVLIK
                     PNLLMKKKPEEATTTHPMVVKVVCEKLLELNCDITIADSPGGPYNQNSLKSIYKASGI
                     EEVANELGIKLNYDVSDVKIHSEKAHVLKYMDIIKPIVDSDYIINLCKLKTHIMATFT
                     GGTKNLYGCIAGLKKAEIHYRFPTEELFCENVLLDICDYIKPTLTIMDGIVGMEGDGP
                     SAGTTREIGVLLASQNPYAIDVVACKIISLLPNKVATIRGAIKRGYIQEDFSDIEILG
                     EDIKDLIIKNYKIPNVSKDLRLFSVKLPKFLNEPISKLITPKPVVRFQDCIKCGKCKE
                     ACPASTIEIGTKGAIIDLSKCIRCYCCHELCPKKAIDVKRNFVFKYVK"
     gene            1721..2986
                     /locus_tag="KRH23_002694"
     CDS             1721..2986
                     /locus_tag="KRH23_002694"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004151 - dihydroorotase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HHS5225972.1"
                     /translation="MILIKNGRVIDPKSQRDENIDLIIKENKIYKIGKFDESDEYEKI
                     IDASGNVVAPGLVDVHVHFRDPGFTYKEDIESGAKSAARGGFTTVICMANTNPIVDNE
                     DTFNYVKEKSKNACINVLQAAAITKGFEGKELVDMEALKKAGVPGFTDDGLPLMDSNL
                     IMEAMIKAKELDVPLSFHEEDPSLVGNPGVNAGKVASELGLKGASSVAEDVMVARDCM
                     LALKTGAKVDIQHISSGVSVDMVRFAKYLGANVVAEASPHHFTLTEEDVLEFGTNAKM
                     NPPLRSKWDRDKIIEGLNDGTIEIIATDHAPHSKEEKDREFIKAPSGIIGLETSLALG
                     ITNLVHKNHLSMMQLIEKMSINPAKLYNLNIGFIEEGAVADIVIFNPEEEWTVESFVS
                     KADNSPFKGKSLYGKVNYTICNGEIVYNA"
     gene            complement(3272..4504)
                     /locus_tag="KRH23_002695"
     CDS             complement(3272..4504)
                     /locus_tag="KRH23_002695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHS5225973.1"
                     /translation="MSLLKNSLANLKGHKLRVFVALLWIIIGITSVILVSSIGNGFQK
                     EIKKSVNNVNPNKTTISFESADNTGLTDDMSIFLKPFNAKDLEELSFVEGVERIAPSR
                     DGFNLDSVYSSQASFDKKTTYVDVGPVKKDSKINLICGRDFSLDDEKRKVILLTLQST
                     SEIFENPEDALGHGININGTIFEIIGVLDDSQQNQAGGFFGGYQDMQFTTSLVPKKAF
                     DTLMSQNSYSNEIYQLDLVSSKGYNVNEVANNVIAKLYEMHPGINGSYTTPDPTEQTA
                     YLESINSNVNKYVSIITVVAMFVGGIGVMNIMYVSVMERQREIGIRRAIGAKPRSILF
                     QFLVEAVFITVCGGILGTIIGFAATNYVSKYIGFEAIPSLNSLFYAIVATILTGVVFG
                     LIPAFKASKLDPIKAIYK"
     gene            complement(4507..5181)
                     /locus_tag="KRH23_002696"
     CDS             complement(4507..5181)
                     /locus_tag="KRH23_002696"
                     /EC_number="7.6.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHS5225974.1"
                     /translation="MLIKLENIQKYYKVGKDELHVLKSLNLEIESGEFVMIMGKSGSG
                     KTTLLNILGFLDVFDEGRYIFDGTDVTNLSENERSVFRNINIGFVFQQFNLIETLNVY
                     QNVELPLIYNKALKKSNREEIVKDKLSSVGLLDKLKQKPLQLSGGQQQRVAIARCLAN
                     DPQIIFADEPTGALDSETSREIMELLTRLNKQGKTIIMVTHDQDLTKYATKVIRLKDG
                     VFTSEV"
     gene            complement(5189..6418)
                     /locus_tag="KRH23_002697"
     CDS             complement(5189..6418)
                     /locus_tag="KRH23_002697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_function: GO:0042802 - identical protein binding
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HHS5225975.1"
                     /translation="MSFLKKFKNKRFRNNSFKSNNFRNSSFGSSGFKSKNKGFKNNPF
                     KNKRFKIYAGIAVIILLILGVLAYVDSKNTELQANENFIETYTIPENEKIFINGMVVP
                     KQTKDFNISGDYELSDVNVTNGQKVNQGDLLFTAKNPTIIAEIDSLKSQLSQYKKQKI
                     SLSDIAENKDAIASINAQITALNSQIASLDKKAYDRVTAPFDGTVYLNDQTGNPDQPV
                     SFMTIQGLEFYMKGQASEQDLPKMKIDQMVNILVFSTDQKLTGRISFISDKPSTPNTE
                     MGAQQNTLSYYDINIAFDNQEGLVNGFHLQASLEVANSSFKIPASCVLKDNKHSYVFK
                     DLDGILKKQIVDVASQNDDFAVVRGGLEQGDIIIKHPTKEMKEGDPVQGDGVTAGSNN
                     GDTTPNKKVEEVTMDVN"
     gene            complement(6530..7534)
                     /locus_tag="KRH23_002698"
     CDS             complement(6530..7534)
                     /locus_tag="KRH23_002698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HHS5225976.1"
                     /translation="MSFKDFLKDKLGFLVYNFTFLIFTVSVIIFSPVDVFLTDTILYI
                     LVVNVVFLFLYLFISYIKKNKFLDKIKNDTFKINMNDIELARCKNEEKIYLNIIKNHQ
                     YQCNNIINNNIKKFEENKEILNMWVHDVKIPIAIIKLILEQNENLIDEKISDDIDSEI
                     FRIENSVEKILYLSRLEDFHKDFLIQEVNIEKIIRNIIKKYSKYFISKKIILDLNNLN
                     FKVLSDEKWLYFIFEQLLSNSLKYSSLGDNISIYCKRTKNYLQLRVEDTGCGIKKEDL
                     NRIFNKGFTGNNGRNNSKSTGLGLYLVKELCDKLGHKIDVDSEYNQYTKFTITFKCDL
                     "
     gene            complement(7558..8232)
                     /locus_tag="KRH23_002699"
     CDS             complement(7558..8232)
                     /locus_tag="KRH23_002699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HHS5225977.1"
                     /translation="MFKIMVVEDDVSLKNIIAKCLTKWGHDVHQIENLENIIEEFKNY
                     NPELVLLDINLPFYDGFHWCNEIRKISKVPIIFISSRNSNMDVIMGVNLGADDYIQKP
                     FSVDVLVAKVNALLRRTYNFVDNNSNQIIHNGVTLDLSTATINYEDNTIELTKNEIKI
                     LHELMKYKGQIVSRNKLMKKLWDNDWFVDDNTLTVNVNRIRSKLNEIGLEDFIETKRG
                     LGYIIS"
     gene            8520..9287
                     /locus_tag="KRH23_002700"
     CDS             8520..9287
                     /locus_tag="KRH23_002700"
                     /EC_number="7.6.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHS5225978.1"
                     /translation="MEEILSVENIKKEYGRKGSKHEALRGITFKVYKGEFVGIMGSSG
                     AGKSTLLNIISTMDLPSSGDIYINGKNTIKMKQNELADFRRDNLGFVFQDSNLLDTLT
                     IKENIMLPLSLKNERVSVIENRIKEISKELNIESILDKYPGEVSGGQKQRGAVCRAIA
                     TKPSLVLADEPTGALDSKSARDLLNCLLKLNKDSNKTILMVTHDAISASFCNRILFIK
                     DGIIFTEIVKGESNREFYNKIVNTVSLIGGVNKNDFI"
     gene            9274..11211
                     /locus_tag="KRH23_002701"
     CDS             9274..11211
                     /locus_tag="KRH23_002701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHS5225979.1"
                     /translation="MTLFRIAMQNVKNSFFNYLMYFISIVFSVFVFFSFKSIEYNEAL
                     SSLGEKTRMSINTSSIVIVVFVFLFIYYSNSFFFNRRRREVGTYSLLGMRKNQIGKIF
                     LYETFLMGIVAILIGIFLGLLFSKLMTMMLVKLMNEMIVVNMNLSIKALVQTLAVFLI
                     IFIVIGIRNTIVIRNKRIIELFNKYPEKYKFKKFIKLKCVLGVLLIAISYLMSISYFI
                     AENIMLSVFILVTIIPGTFLFFSSTMYMIIDAVKKRKSFYYKGQNLIAFSELGFKLKS
                     NSSVLAVIAILIATSVTMLGFTISLYYDIDRNISENYKYSYTINLGNSYVNNEIDKLL
                     YKYKKDNKIIFDKTIELIDKDINIEMYYKNGNSYIEDRTSVDIIRESDFKKLRQYQNN
                     NYEELTSKESVYYVSDSYKKIFFKDFEIEKINLHIKDANEYDINLFKVQKSILEPEIN
                     SQATFDLIVVKDDVFNQLKLHGNSRLIRLIDIKNEKKELDLTLKLKNIVSENMKFTYP
                     FNFTSSIESYNNLIKLSGLMLFIGIFLSVVFLLCTGSIILFKQLSNIYDDKERYIMLI
                     KLGANNKDIEKIISKQLKVIFLMPLVVGTVHNLFAMSIAQKFIPRSLLVPIIITLVIY
                     FIGYFIYYFLTLKYALNMIKE"
     gene            11436..13049
                     /gene="ggt"
                     /locus_tag="KRH23_002702"
     CDS             11436..13049
                     /gene="ggt"
                     /locus_tag="KRH23_002702"
                     /EC_number="2.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0036374 - glutathione hydrolase activity
                     [Evidence IEA];
                     GO_process: GO:0006750 - glutathione biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0006751 - glutathione catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyltransferase"
                     /protein_id="HHS5225980.1"
                     /translation="MKFNAYQHKYSSIRNVVYAKNGAVATSTPLASQAGLEILKKGGN
                     AVDAAVATAATLAVVEPTSNGIGGDAYALVWIEEEKRLYGLNSSGFAPENMELKNYNN
                     MKEMPKYGFGAVTVPGIPAAWSELNKKYGKLSLMECLSPAINYAREGYVVSPNVAKVW
                     KKSYELYEKELIGEEFKPWFDTFSKDGKAPEAGDIFICEEQASTLEEIADTQAESFYR
                     GRLADKIDEYSKKFNGAIRKSDLECFYPTWVEPISTEYKGYKIFEIPPNGHGITVLMA
                     LNILKELELEGNIENVEDIHKIIESLKLAFADSKTYVTDIEHMKVKIQELLSQEYAKK
                     RSLLIDNKEALYPTAGEPYCGGTVYLCTADKDGNMVSYIQSNYINFGSGIVIPRTGIA
                     LHSRGNNFNLDPKHHNVVKPFKKPYHTIIPGFLGKEDKAIGPFGVMGAFMQPQGHIQV
                     LTNMIDFGLNPQEALDAPRWQWIKGKEIEVEPEMPKHIIDSLIEKGHEIKVIHDTVDM
                     GRGQIIFKTEQESYICGTESRCDGHIAVY"
     gene            complement(13182..14033)
                     /locus_tag="KRH23_002703"
     CDS             complement(13182..14033)
                     /locus_tag="KRH23_002703"
                     /EC_number="2.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016783 - sulfurtransferase activity
                     [Evidence IEA];
                     GO_process: GO:0000098 - sulfur amino acid catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase"
                     /protein_id="HHS5225981.1"
                     /translation="MKNIISAKELISKLEKNDNLVVIDCRFDLINRTYGIDSYKKGHI
                     KGSFILDIDKDLSSPTKEHGGKNPLQDPLILKEKLEKMGVDNDTTIVTYDDGDLNGAC
                     RLFFQLKHLGLKNVYVLDGGITSFVKEGGELEEKVNIPSCTSKEIRPNINNDLVVPME
                     YVKSKLYKKDTVIIDCRANERYQGLVEPAYSKAGHIPSAKNYFCKDLIKSDFENGSLK
                     DIEFLKKFFKDLNNYDEVILSCGSGISACVNSLALRELDIPHKIYIGSFSDWISYDDN
                     EIKTGQE"
     gene            14659..15552
                     /locus_tag="KRH23_002704"
     CDS             14659..15552
                     /locus_tag="KRH23_002704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfide/dihydroorotate dehydrogenase-like
                     FAD/NAD-binding protein"
                     /protein_id="HHS5225982.1"
                     /translation="MSNKIVSKRQLTDSIYLMEIEAPRVAKSSQPGQFIIIKNDEKGE
                     RIPLTIADYDREKGTVTIVFQTVGASTKKLAMFEENDFVMDFVGPLGQASEFIHEDIE
                     ELRNKKILFVAGGVGSAPVYPQVKWFKEHGLDVDVIIGARTKELIILEDDMKKVAKNV
                     YVSTDDGTYGFNGRVTDLLKDLVDNQGKKYDQAIVIGPMIMMKFMCQLTKELNIPTIV
                     SLNTIMIDGTGMCGGCRVSVGNETKFACVDGPEFDGHLVDFDQAMRRQSMYKTQEGRA
                     MLKLEEGDSHHHSNCGCGGNK"
     gene            15552..16946
                     /gene="gltA"
                     /locus_tag="KRH23_002705"
     CDS             15552..16946
                     /gene="gltA"
                     /locus_tag="KRH23_002705"
                     /EC_number="1.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004355 - glutamate synthase (NADPH)
                     activity [Evidence IEA];
                     GO_process: GO:0006537 - glutamate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent glutamate synthase"
                     /protein_id="HHS5225983.1"
                     /translation="MDAKKVKVPVREQEPAVRATNFDEVCLGYNKEEAMAEANRCLAC
                     KKPKCVGGCPVGIDIPGFITKIKEDDIEGAAKVIAKSSSLPAVCGRVCPQESQCEGVC
                     ILGIKSDAVSIGKLERFVADWSKENDINLSDTEPKKNQKVAVIGSGPAGLACAGDLAK
                     KGYDVTIFEAMHEPGGVLTYGIPEFRLPKQAVVQPEIDNIRKLGVKIETNVIVGKTIT
                     VDELIEDEGFEAIFIGSGAGLPMFMNIPGENANGVFSANEFLTRVNLMKAYRDDYDTP
                     ISSGKKVAVVGGGNVAMDAARTALRLGSESYIVYRRSEKELPARAEEVHHAKEEGIIF
                     NTLTNPKEILVDENGYVKGMVCIRMELGEPDDSGRRRPIEIEGSEFVLDVDTVIMSLG
                     TSPNPLISSTTKSLDINKKRCLITDENGQTSKEGVFAGGDAVTGAATVISAMGAGKTA
                     ASSIDEYLKAKVNA"
     gene            17312..19531
                     /locus_tag="KRH23_002706"
     CDS             17312..19531
                     /locus_tag="KRH23_002706"
                     /EC_number="2.7.7.65"
                     /EC_number="3.1.4.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0052621 - diguanylate cyclase activity
                     [Evidence IEA];
                     GO_function: GO:0071111 - cyclic-guanylate-specific
                     phosphodiesterase activity [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="HHS5225984.1"
                     /translation="MKKREKVFDGLVFKHILILLILLVLIDLTSTIIYASNSMEITSR
                     NMIEASKRELENYLEVNISLLKALSQDDRFSNGETSLIEKEKLLSPYQKEYNLFMIGI
                     TDTKGNASSTYRENVNSIKDKPSFKKAIKTKQVVVSDIEVSNVTGDKVFIIYVPIVKN
                     NEMIGTIFASFYFQDVNNLISRSNFDDSIKFLMIDKDYTIISHPNKKYVNDKSKMLDL
                     EGNIIGTTKSEILKNINKKCQGDFLSWDNWRLYNVKYTNVKWTNWTLVSKCNIFKNFK
                     NLIVNFMIKLYFYIVIFMILWKLSNAKLIEQLKKLAYYDSLSGIKNKEKFRKDSMYIL
                     KNYYQDNFYLVQLDVNKFKYINEMFGYAEGNKILIHISQVLNNNTNKYEICARMDNDH
                     FILLIACNTEDELLNRLSKINKEICNLNTTNSSKYKIVMSSGIYKITKKDDIKKIDLL
                     IDRANIAAKSKKEKYEHSYSFFNEDTRNRLYKEKRLEDNMNKALEKGEFIVYYQPKYS
                     LDDVNEIEGAEALIRWNSPEFGFISPIDFVPLFEKNGFIVNIDMFVFEEVCKTLNKWI
                     NKGYTPVPISVNMSRVHLYRDNFIENITDLISKYNISPEFIELELTESVVFDNLNILI
                     DIMKKIKEIGFLISMDDFGSGYSSLNLLKDLSFDILKLDRGFLIETTDTKRGKIIISK
                     IVEMAKAIDIKVICEGVETYEQVEFLKEIGCDKVQGYLFAKPMVLDEFEKHLNFKFD"
     gene            19678..20424
                     /locus_tag="KRH23_002707"
     CDS             19678..20424
                     /locus_tag="KRH23_002707"
                     /EC_number="7.6.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014466367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHS5225985.1"
                     /translation="MNILSIRNISKTYCGNIPFKALDKVSLNIEKGEFVSVMGPSGSG
                     KSTLLNIISTVDRQSEGEVVLDGYDVSKLKGEKLAEFRRKQLGFVFQDFNLIDTLTVG
                     ENIMLPLTLEGASIKDMNIQTKSISKFLGIDKILDRKTYEISGGQAQRCAIARAIINK
                     PAILLADEPTGNLDSKSTDDVLKLFTRINKEQNVTTLMVTHEAYSASYSDRVIFIKDG
                     CIYTEIKKSESNNSFYSDILAVLSQIGGVR"
     gene            20424..22304
                     /locus_tag="KRH23_002708"
     CDS             20424..22304
                     /locus_tag="KRH23_002708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HHS5225986.1"
                     /translation="MDFRKFAYNNIVRNFRAYLAYFLSSVFSIMIFFVFAVSMFHPII
                     TKSGMQSGSTAFMALMTSELIILGFSLLFILYSLGNFLKYRLKDFGVLMIIGMSNRQL
                     KKLILIENLIIGFLAVMLGILLGLSISKLFLLYLSKLFYMNLTEFYFPVKAMLLTIVS
                     FMILFLITGPMSLKLLSKKSILELLVGTKKPKKEIKSSKLFGIIGVICLILGYAMILF
                     GNKLKINGGMYTTALLITLGIFLFFSQFTILILKYLKNKEKFYKNKVNMLLISNLIYK
                     LKDNTRLLFLITILLSATLVAFTTTSTLVSSQGEASKNNFPMVYSYFSEHNNEKEYEE
                     LQQIREAIKGYDYKELSFPVLKYNREVLLSVKNYNKLSKELGLDKISSKLEKYEGIII
                     PSSNSQEHINSLKQLKNYSIKNLNIEVKKSKNKIIFPTGLFSKVVVISDDLYNEVKGE
                     FSKINFHGFDYKNWQSSAKITENLKEKHFNLDREYNRSYFLTLPDMYLVELQQSKILQ
                     FMGVFIGVILFIAVFSFLYFRLYTDEIEDNVKYKKLSKIGLSFKNMNKIVSIEIGTLF
                     FIPYFIAIINSIISLLFLNQVLNNSFKLENLGILLLISSIYSLYFYLLKKIYTRKVWF
                     FD"
     gene            22423..23814
                     /locus_tag="KRH23_002709"
     CDS             22423..23814
                     /locus_tag="KRH23_002709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA];
                     GO_function: GO:0042910 - xenobiotic transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006855 - xenobiotic transmembrane
                     transport [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HHS5225987.1"
                     /translation="MENQQLLGTERISKLLLKYSIPAIIGMLVNSLYNVVDRIFIGNI
                     PGVGPLAITGLGVTMPIMTIILAFGMLIGIGTTTTISIKLGQGKVEEARKLIGNAMTL
                     SVITGIIIMILGILFANKILTLFGASENTLIYAKSYINIILLGTVVNLLSFSLNHSIR
                     ADGSPKISAGIMIVGCLTNIVLDWILIFGFNLGIQGAAIATVTSQALTAILTIGYYIS
                     GKSNLRFSKSNLKLDKKLIKAVFAIGMSPFAMQLAASLVQVISNIALKTHGGDLAIGA
                     MATISSIAMVFLMPIFGINQGAQPIIGFNYGAEKYDRVKKAYLGSLVVATIILCMGMV
                     VVMLFPEAIIGIFNKDPELMNISVNGLRIYLLMLPIVGLSVTGTNFIQSIGKAKMAML
                     LSLLRQVILLIPAVLILPTFLGLQGVWTAQPVSDFIATVITGIVVFRELKRYTPKTEK
                     LNENERLNEITTE"
     gene            23921..24961
                     /locus_tag="KRH23_002710"
     CDS             23921..24961
                     /locus_tag="KRH23_002710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HHS5225988.1"
                     /translation="MEFTKKSKLKNMYVNMNVARMLSKINEYKGRQLLYKKQPKEILE
                     NLEKKSLVDCSESTYIGNQRDSSNFNLEKLISNEVTPRSREELSIVEYRDVVKTINSA
                     YESIPISSQTILELHGYLYKFSSTRGGSYKSDNDFIEHNLKPSEFISIDSSGNKVEKA
                     VEEICEAYNTLIEEDEIDILILISAFVLDFILIHPFKEGNIKMARVLILLLLNKNGYE
                     VGRYISLGKIFDDSSYEYYSNLNYLKASIGSEKADMNAWIEYFLETILTAYEKLDDSL
                     NISDKKRQTKTSRIEKIINSTLGYFTKEDIRDLCPDIPEPTINRVFNNLRKQDKIEVV
                     ARGRSAKWKKKY"
     gene            25450..26103
                     /locus_tag="KRH23_002711"
     CDS             25450..26103
                     /locus_tag="KRH23_002711"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008753 - NADPH dehydrogenase (quinone)
                     activity [Evidence IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050136 - NADH:ubiquinone reductase
                     (non-electrogenic) activity [Evidence IEA];
                     GO_function: GO:0050446 - azobenzene reductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-dependent NADH-azoreductase"
                     /protein_id="HHS5225989.1"
                     /translation="MKKKLLYINVNSKPEDLSSSKTVARKFINKFMEKNKDFEVEEID
                     LYKEHIPRLEYQYFEKRNSIVSEENAKNLDDKDRKELTKIRNLCDQFVNASVYVIAAP
                     MWSLSFPAPLKEYIDCIIQDGKTISFEGNDKPQGILNDIDRSMVYIQSSGGHIPWVLK
                     PVMNKGLNYVESIMKFIGIKKFDELLVDGTGTSEEERQAAIEKAAEKIDGIIDGMKF"
     gene            26179..26388
                     /locus_tag="KRH23_002712"
     CDS             26179..26388
                     /locus_tag="KRH23_002712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5225990.1"
                     /translation="MREEKSNEKYDCYWCNQENNFCVEIKDNIVMIDDGTGTLKQAVF
                     IGYKQIQINLNCSHCQNLNRIKLNL"
     gene            complement(26528..27094)
                     /locus_tag="KRH23_002713"
     CDS             complement(26528..27094)
                     /locus_tag="KRH23_002713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HHS5225991.1"
                     /translation="MMNNELNTIILETLNNADITSNDIPSIDLYMDQIISLIDNKLSA
                     NKRFESDKILTKTMINNYSKEGLIKPVKGKKYTKEQILQMIIIYSMKNTLTIQEIKRI
                     LHGVYEKDNFSEKDLVSCYEKFMLIKENQRKNIPDFIESNFENISINPENKDDLLITL
                     LSLTSMADQLKNISEKLVDRYFPDITKK"
     gene            27255..27908
                     /gene="trhA"
                     /locus_tag="KRH23_002714"
     CDS             27255..27908
                     /gene="trhA"
                     /locus_tag="KRH23_002714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0019835 - cytolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PAQR family membrane homeostasis protein TrhA"
                     /protein_id="HHS5225992.1"
                     /translation="MYQFFLKGRDPISSLTHFIGACLSLLATIILVFQSVTLQETSLL
                     MIVSVSVFGLSLIALYSASSYYHFLKGTPEQELFFRKVDHAMIYVLIAGSYTPICLNF
                     MEKKEGIIFVTAIWIVAFIGIIIKIFWMDAPRWLSTSIYLLMGWAIVFDINAFNSIPK
                     DCLRLLIMEGVSYSIGAIIYIIKKPNISPEFGFHEIFHIFIMIGSLFHFLAVLLYVL"
     gene            complement(28066..28242)
                     /locus_tag="KRH23_002715"
     CDS             complement(28066..28242)
                     /locus_tag="KRH23_002715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5225993.1"
                     /translation="MYKYDDYVNLTNDLDLPVEIRNKCVRIVSVSENLEDIIIVHKFK
                     LYVVNEKYIKGIME"
BASE COUNT        10814 a         3192 c         4554 g         9813 t
ORIGIN      
        1 gatgaacata gaataggagt agctcaaggt gtagatgcag aaataatcga aggattaaga
       61 gccaacttta ctggtgagtg tacagaagta ggaatgtatt tagcaatgag tagacaagct
      121 gatagagaag gttatccaga agtagctgaa gcgtataaga gaatagcttt tgaagaggct
      181 gaacatgctg ctaaatttgc agaacttctt ggagaagttg tagttgcaga tacaaaagaa
      241 aacttaagag ttagagttga tgctgagtat ggtgcaactg atggaaaatt aaaattagct
      301 aagagagcta aagaattagg attagatgct atacatgata cagtacatga aatgtgtaaa
      361 gacgaagcta gacatggtaa agcattctta ggattattaa acagacattt tggaaaataa
      421 taattaaaac aattaaaaca tagattaaaa ggagaaactt tggtttctcc ttttttaaat
      481 tatacaaata aactgttgtg atagaaggat ggagataata tgaagtcggt atctgttagg
      541 agttgtaaaa cttacaatta tgaagaagta aagttatcta ttgaaaaaaa tttagaggat
      601 attggtggta tagataagtt tgttaaaaaa ggaagcaaag tacttataaa accaaattta
      661 ttgatgaaaa aaaagcctga agaagctaca actacacatc ctatggttgt aaaagttgta
      721 tgtgaaaaac ttttagagtt aaattgtgat attacaatag cagatagccc tggtggtcca
      781 tataatcaaa attctcttaa gagcatttat aaggcatctg gaattgaaga agtagcaaat
      841 gaactgggca ttaagttaaa ttatgatgtt tcagatgtta agatacatag tgaaaaagca
      901 catgttctaa aatatatgga tattattaaa ccaatagtag attcagatta tataataaat
      961 ctttgtaaat taaagactca tataatggca acttttactg gtggtacaaa aaacttatat
     1021 ggatgcatag ctggattgaa aaaagcagag atacattata gatttcctac agaagagttg
     1081 ttttgcgaaa atgtactttt agatatttgt gattatataa aaccaacatt gacaattatg
     1141 gatggtatag taggtatgga aggtgatgga ccttcagctg gtactactcg agaaatagga
     1201 gttttattag catcacaaaa tccatatgct atagatgttg ttgcatgtaa gattataagt
     1261 ttacttccaa ataaagttgc tacaattaga ggtgctatta agagaggata tatacaagaa
     1321 gatttttcag atattgaaat tttaggtgaa gatataaaag atttaattat aaaaaattac
     1381 aagattccaa atgtaagtaa agatttaaga ttgttttccg taaagctacc aaaattttta
     1441 aatgaaccta tttcaaagct tataacacca aagcctgtgg taagatttca agattgcata
     1501 aaatgtggaa aatgcaagga agcttgtcct gcatccacta tagagatagg gactaagggt
     1561 gctattatag acttaagtaa atgtataaga tgttactgtt gccatgaact ttgtcctaaa
     1621 aaggctattg atgtcaaacg taattttgta tttaagtatg taaaataatg tataatatta
     1681 tatgagtcta tataaattaa aaatataaag gagaaataat atgattttaa ttaaaaatgg
     1741 tagagtaata gaccctaaaa gtcaaagaga tgagaatatt gacttaatta taaaagaaaa
     1801 taaaatttat aaaataggca agtttgatga aagtgatgaa tatgaaaaaa taatagatgc
     1861 tagtggtaat gtagttgctc caggtttagt ggatgtacat gtacacttta gagaccctgg
     1921 gtttacatat aaagaagata tagaaagtgg agctaaatct gctgctagag gtggatttac
     1981 aactgttata tgtatggcaa atactaatcc tattgtagat aatgaagata cttttaatta
     2041 tgttaaagaa aagtcaaaaa atgcatgtat aaatgtttta caagcagcag ctataactaa
     2101 aggttttgaa ggtaaagagt tagttgatat ggaagctctt aaaaaagctg gtgtaccagg
     2161 gtttactgat gatggattac ctttaatgga tagcaatcta attatggagg caatgattaa
     2221 ggcaaaagag ttggatgtac cacttagttt tcatgaagaa gacccttctt tagttggaaa
     2281 tccaggtgta aatgcaggaa aggtagcttc agaacttgga ttaaaaggtg catcaagtgt
     2341 agcagaagat gttatggtag ccagagattg tatgttggca ctaaagactg gtgctaaagt
     2401 tgatatacaa catataagtt caggtgtatc tgttgatatg gttagatttg caaaatactt
     2461 aggtgcaaat gtagttgcag aagcttcacc acatcacttt acattgactg aggaagatgt
     2521 attggagttt ggaacaaatg caaaaatgaa tccacctcta agaagtaaat gggacagaga
     2581 taagattata gagggattaa atgatggtac tattgaaata atagcaacag accatgcacc
     2641 tcatagtaaa gaagaaaaag atagagagtt tataaaagct ccaagtggaa ttattgggct
     2701 tgaaacttct ttagctcttg gaataacaaa tttggtgcat aaaaatcatc ttagtatgat
     2761 gcagttaata gaaaaaatgt ctataaatcc tgcaaagttg tacaatttaa atattggatt
     2821 tatagaagaa ggggctgtag cagacattgt tatattcaat ccagaagaag aatggacagt
     2881 tgaaagcttt gtttctaaag ctgataattc accgtttaaa ggtaaatctt tatatggaaa
     2941 ggttaattat acaatatgta atggggagat tgtatataac gcctaattta agattatttt
     3001 tttaaggcgg agtgtacaat gattgaaagt aaaagattgt atattagcag aatgagattg
     3061 attaatcaaa attggaagta ttagtttgaa caattagaac ataacatctt ggtaatttag
     3121 atatagtaag gaagagaatc ctttttatga aagaacgcac tattatattt ggaaagatta
     3181 agttcctaat ctatcatata taatagtgcg ttatatattt aagtatgttt tatataaact
     3241 aatctaaaaa tcgaaaatct ttatacaatt tctacttata aattgccttt atagggtcta
     3301 gtttagaggc tttaaaggct ggaatcagac caaatacaac tccagtcaat atagtagcta
     3361 caattgcata aaataagcta tttaagctag gtatagcttc aaaacctata tatttagaaa
     3421 catagttagt agcagcaaat ccaattatag ttcctaaaat tccaccacat actgttataa
     3481 aaacagcttc aactaaaaat tgaaataata tagacctagg ttttgctcca atagcacgtc
     3541 ttataccaat ttctctttgt ctttccataa cagatacata cattatattc attacaccaa
     3601 taccaccaac aaacattgca actacagtta ttatagatac atatttgttt acattggaat
     3661 taatgctttc aagataagct gtctgttcag ttgggtctgg tgtagtataa gaaccattga
     3721 taccagggtg catctcatat aatttagcta taacattgtt tgcaacttca tttacattat
     3781 agcctttaga agaaactaag tctaactggt aaatttcatt tgaataagaa ttttgactca
     3841 ttaaagtgtc aaaagccttt ttaggtacta gagaagtagt aaattgcata tcttggtaac
     3901 ctccaaagaa tcctccagct tggttttgct gagaatcatc taatacccct attatttcaa
     3961 atatagttcc atttatgttg ataccatgac ctaaggcatc ttctggattt tcaaaaattt
     4021 cacttgtact ttgtaatgta agtaaaatta cttttctttt ttcatcatct aaagaaaaat
     4081 ctctaccaca aattaaattt attttagaat ctttttttac tggtccaaca tcaacatacg
     4141 tagttttttt atcaaaagat gcttgtgaag agtaaactga atcaaggtta aacccatctc
     4201 ttgaaggagc tattctttct actccttcaa caaatgataa ttcttctaaa tcttttgcat
     4261 taaagggttt taaaaaaata ctcatatcat cagtaagacc tgtgttatcg gctgattcaa
     4321 acgaaatagt agttttatta gggtttacat tgtttacaga tttcttaatt tctttttgaa
     4381 atccattacc tatagaacta acaagtatta ctgaagttat tcctattata atccagagta
     4441 aagctacaaa tacacgaagc ttgtgacctt ttaaattggc caaagaattt tttaataaac
     4501 tcatgattac acctccgaag taaacacacc atctttaagt cgtataacct tagttgcata
     4561 cttagttaaa tcttgatcat gtgtaaccat tattatagtc ttaccttgtt tgttgagcct
     4621 tgttaaaagc tccataattt ctctgctagt ttcactatct aatgccccag tcggttcatc
     4681 agcaaagatt atctgagggt catttgctag gcaacgtgca atggctacac gctgttgttg
     4741 accaccagat aattgaagtg gtttctgctt aagcttgtcc aaaagcccaa cagaacttaa
     4801 tttatcttta acaatttctt ctctattaga tttttttagt gctttattgt aaattagagg
     4861 caactctaca ttttgatata catttagagt ttctattaaa ttaaattgtt ggaaaacaaa
     4921 tccaatatta atatttctaa aaacagaacg ttcattttca ctcaaattag ttacatctgt
     4981 tccatcaaat atatatcttc cttcatcaaa tacatctaga aaacctaaga tattaagtaa
     5041 agtagtttta ccactaccag acttacccat tatcatgaca aattctccag attcaatttc
     5101 taaatttaag gattttaaaa catgtaattc atctttccct actttgtaat atttttgaat
     5161 attttctaat ttaattaaca tatgtaaatt aattcacatc catagtaact tcttctactt
     5221 ttttgtttgg agtagtatct ccattattag aaccagcagt tacgccatcg ccttgaactg
     5281 ggtctccttc tttcatttct ttagtagggt gttttattat tatatcgcct tgttcaagac
     5341 cgcctctaac tacagcaaaa tcatcatttt gacttgctac atctacaatt tgctttttca
     5401 atataccatc taaatcctta aatacatatg agtgtttgtt gtctttaagt acacaagatg
     5461 ctggtatttt aaagcttgaa ttagctactt caagtgatgc ttgaagatgg aatccattta
     5521 ctaatccttc ttgattatca aatgctatgt ttatatcata ataagatagt gtattctgct
     5581 gagctcccat ttcagtattt ggagtagatg gtttatcaga tataaaactt attctaccag
     5641 taagcttttg gtcagttgaa aaaactagta tattgaccat ttggtcaatc ttcattttag
     5701 gtaaatcttg ttcacttgct tgtcctttca tataaaactc tagaccttga atagtcataa
     5761 atgaaactgg ttggtctgga tttccagttt ggtcattcaa gtatactgtg ccatcaaaag
     5821 gagcagtaac tctgtcataa gcttttttat ccagagaagc tatctgagag tttaaagcag
     5881 ttatctgtgc atttatagaa gcaatagcat ctttattttc agcaatatca gaaagtgata
     5941 ttttttgttt tttgtattga ctaagttgtg attttaaact atctatttct gctattatag
     6001 ttggattttt agcagtaaaa agaaggtctc cttgatttac tttttgacca tttgtaacat
     6061 taacatcact taactcataa tctccagata tattgaagtc cttagtttgc ttaggaacaa
     6121 ccatcccatt tataaatatt ttttcatttt caggaatagt atatgtttcg ataaaatttt
     6181 cattagcttg taattcagtg tttttcgaat caacataagc aagaactcct agaattaaaa
     6241 gtatgattac tgctattcct gcatatattt tgaatctctt atttttaaag ggattgtttt
     6301 taaaaccttt atttttagac ttgaagccac tacttccaaa actgctattt ctaaagttgt
     6361 tacttttaaa actgttattt ctaaatcttt tatttttaaa tttttttaga aaagacatgt
     6421 cttcctcctt tttataaaaa ctacttaatt atatactggg atgtacatat agaattacta
     6481 taagaagttg aatataattt aatgaaaata aactatcaat aataagatac tataaatcac
     6541 atttgaatgt aatagtaaat tttgtatatt ggttgtactc tgaatctaca tcaattttat
     6601 gaccaagctt atcacaaagt tcttttacta aataaagccc aagacctgta gatttagaat
     6661 tgtttcttcc attattacct gtaaatccct tattgaatat tcgatttaaa tcttcctttt
     6721 ttataccaca accagtatct tccactctta attgtaaata atttttggtt cttttgcaat
     6781 agatagatat attatctcct aatgaggagt attttaggga attactcaat aattgctcga
     6841 atatgaagta tagccatttt tcatcagata aaaccttaaa attcaaatta tttaagtcta
     6901 aaataatttt ttttgaaata aaatattttg agtatttttt tataatattt ctaatgattt
     6961 tttcaatatt tacctcttga attaaaaaat ccttatgaaa atcttcgagt cttgataaat
     7021 ataaaatttt ttcaacggag ttttcaattc taaatatttc actatctatg tcatctgaaa
     7081 ttttttcatc aattaaattt tcattttgtt caagaatgag ttttattata gctataggta
     7141 tctttacatc gtgtacccac atatttaaaa tctctttgtt ttcttcaaat ttcttgatat
     7201 tattatttat tatgttgtta cattgatatt gatgattttt aataatgttc aagtatattt
     7261 tttcttcatt tttacatcta gctaattcta tatcattcat attaattttg aatgtatcat
     7321 tttttatctt atctaaaaat ttgttcttct tgatgtagct aataaataga tataaaaata
     7381 aaaacacaac atttacaact aatatatata aaatagtatc agtcagaaaa acatctacag
     7441 gagaaaatat aataactgat actgtaaaaa ttaagaaagt aaaattgtat actaaaaaac
     7501 ctagtttatc cttgagaaaa tctttaaagc tcataaattc acctacttag aattgtttta
     7561 actgattata taacccaatc ctctttttgt ttctataaaa tcttctaaac caatttcatt
     7621 taattttgag cgtattctat ttacattgac agttaatgta ttatcatcta caaaccaatc
     7681 attatcccat aattttttca tgagtttatt cctacttact atctgcccct tatatttcat
     7741 aagctcatgg agaattttga tttcattttt tgttagctca atagtattat cttcatagtt
     7801 tattgttgca gttgataaat ctaaagtaac accattgtga ataatctgat ttgagttatt
     7861 atcaacaaaa ttataagttc ttcttaaaag ggcattaact ttagctacta agacatctac
     7921 agaaaaaggt ttttgtatat aatcatctgc acctaaattt acacccatta ttacatccat
     7981 attagaattt cttgaagaaa taaaaattat aggaactttt gaaatttttc ttatttcatt
     8041 acaccaatga aaaccatcat aaaatggaag gtttatgtcc aataaaacta attctgggtt
     8101 atagtttttg aactcttcta ttatattttc aagattttct atttgatgaa catcatgtcc
     8161 ccatttagta agacactttg ctatgatatt tttcaatgag acgtcatctt caactaccat
     8221 tattttaaac attcttacct cctaattcaa aatagttata ttaacataac tatattctac
     8281 ttgataaatt aaaatatttc taccttatta cctaaaataa ttatattaat ataactatat
     8341 tttacttgat aaattatatt ttaaacataa ttgcaataaa tttgaagaaa tataattaat
     8401 acttacgaaa atgtaacctt aaattaatat aattaaatgt ttaaaagcca ttttaatata
     8461 tataatatat ttgtgagaat tgataaataa ctaattgtga tgaaaggtga ttattaacta
     8521 tggaagaaat attatctgtt gaaaatataa aaaaagagta tggaagaaaa ggttcaaaac
     8581 atgaagctct aagaggaata actttcaagg tttataaagg agaatttgtt ggtattatgg
     8641 ggtcttccgg tgctggtaaa tcaacacttt taaatattat ttctacaatg gatttacctt
     8701 catcaggaga tatttatata aatggaaaga atactattaa aatgaagcaa aatgaattgg
     8761 cagattttag acgtgataat ctaggctttg tatttcaaga ttctaatctt ttggatacac
     8821 ttacaataaa agaaaatata atgttgcctc tttctttaaa aaatgaaaga gtatcagtaa
     8881 tagaaaatag aataaaagag atttcaaaag aattaaatat agaatctata ttagataaat
     8941 accctggcga agtttctggt ggacaaaagc aaagaggagc tgtatgtaga gctatagcaa
     9001 caaaaccatc attagtactt gcagatgagc ctacaggagc attagattct aaatctgcta
     9061 gggatttgtt gaattgtcta ttaaaattaa acaaagacag caataaaaca atattgatgg
     9121 taactcatga tgctataagt gcgagttttt gcaatagaat actctttata aaggatggaa
     9181 taatattcac agaaattgta aagggagaaa gtaacagaga gttctataat aaaatagtaa
     9241 atacagtttc cttaattgga ggagttaata aaaatgactt tatttagaat tgcaatgcaa
     9301 aatgtaaaga atagtttttt taattattta atgtacttta tttcaattgt atttagtgta
     9361 tttgtatttt ttagttttaa atctatagag tataatgaag cgttgagttc acttggagag
     9421 aaaaccagga tgagtattaa tacaagttca attgtaatag tggtatttgt atttttattt
     9481 atatattatt caaactcatt ttttttcaat agacgtaggc gagaagtagg aacttatagt
     9541 ttacttggaa tgaggaaaaa tcagatagga aaaatatttt tatatgaaac ttttttgatg
     9601 ggtatagttg caatactaat aggtatattt ttaggactgt tattttcaaa gcttatgact
     9661 atgatgcttg taaaattaat gaatgaaatg atagtagtaa atatgaactt aagtataaag
     9721 gccttagttc agacactagc ggtattttta ataatattta tagttattgg aataagaaat
     9781 actatagtta tcagaaataa gagaattata gagttattta ataaatatcc agaaaagtat
     9841 aagtttaaaa aatttataaa gttaaaatgt gtacttggtg ttttattaat agctatttct
     9901 tatttaatgt caattagtta ttttattgct gaaaatatta tgctttcagt ttttatatta
     9961 gttacaataa tacctggaac ttttttattt ttttcatcaa cgatgtatat gattattgat
    10021 gctgttaaga agagaaaaag tttttattat aagggacaga atttaattgc attttctgaa
    10081 cttggattta aattaaagag caatagtagt gtattggctg taatagcaat attaatagct
    10141 acaagtgtaa ctatgctagg gtttaccata tcactttatt acgatataga taggaatata
    10201 agtgaaaatt ataaatacag ttataccata aatttaggaa attcttatgt aaataacgaa
    10261 attgacaaat tattatataa atataaaaaa gataataaga taatctttga taaaacaata
    10321 gaacttatag acaaagatat aaatattgaa atgtattata aaaatggaaa tagttatata
    10381 gaagatagaa cgtctgtaga tattattaga gaaagtgatt ttaaaaaatt aagacaatat
    10441 cagaataaca attatgaaga attaacttca aaggaatctg tgtactatgt ttctgattca
    10501 tacaaaaaaa tattttttaa agactttgag attgaaaaaa taaacttgca tattaaagat
    10561 gcaaatgagt atgatataaa tctgtttaaa gtacaaaaaa gcatcttgga gccagaaata
    10621 aattcacaag ctacgtttga tttaattgta gtaaaagatg acgtatttaa tcagttaaaa
    10681 ttacatggaa attctagatt aataagatta attgatataa aaaatgaaaa aaaagaactg
    10741 gatttgactt taaaattaaa aaatatagta agtgaaaata tgaaatttac ttatcctttt
    10801 aattttacat caagtattga aagttataat aacttgataa aattaagtgg tctaatgctg
    10861 tttataggca tatttttgtc tgtagtattt cttttatgta caggtagtat aatcttattt
    10921 aaacaattat caaatatata tgatgataag gaaagatata ttatgttaat aaaacttgga
    10981 gcaaataata aagatattga gaaaataata tcaaaacagt taaaagttat atttttaatg
    11041 ccattagttg taggtacagt tcataattta tttgctatgt ctatagcaca aaagtttata
    11101 ccaaggtcat tacttgtacc aattatcata actctagtca tttattttat aggatatttt
    11161 atatattatt ttttaacttt aaaatatgct ctaaacatga taaaagaata aattattttt
    11221 aagtcaaaag aattagatat atgttttgaa taaaataact tatttaagtg cagatagaaa
    11281 atactagaat tgagtttaag atatttattt aaagacaaaa ttaaagttag gaaaaagtct
    11341 atattttata tcattttgta tcagttacat tacttgatgt tatataataa atctaagcag
    11401 aatatcaaat aaaaaatgac gaggagctga aatttatgaa gtttaatgcc taccaacata
    11461 aatactcatc aataagaaat gtcgtgtatg ctaaaaatgg agcagttgca acatcaacac
    11521 cattagcatc tcaagctgga cttgaaatac taaaaaaggg tggaaatgct gttgatgcag
    11581 cagttgcaac agccgccaca ttagcagtag tagaacctac aagcaatggg attggaggag
    11641 acgcatatgc ccttgtttgg atagaggaag aaaaacgatt gtatggttta aattctagtg
    11701 gctttgctcc agaaaatatg gaattaaaaa attataataa tatgaaagaa atgccaaaat
    11761 atgggtttgg agcagtaact gtacctggaa taccagcagc ttggtcagaa ttaaataaaa
    11821 aatatggtaa acttagctta atggaatgct tatctccagc gataaactat gcaagagagg
    11881 gatacgtagt atctcctaat gtagctaagg tatggaaaaa atcatatgaa ctctatgaaa
    11941 aagaacttat tggagaagag ttcaaaccat ggtttgatac attttctaaa gatggtaaag
    12001 ctccagaggc tggagatata tttatatgtg aagaacaggc aagtacatta gaagagatag
    12061 cagatactca ggctgaaagc ttttatagag gaagacttgc tgataaaata gatgaatatt
    12121 ctaaaaaatt taatggggct ataagaaaga gtgacttaga gtgtttttat ccaacatggg
    12181 tagaacctat aagtacagaa tataagggat ataaaatatt tgaaatccca ccaaatggtc
    12241 atggaataac agttttaatg gcacttaaca tattaaaaga attggaatta gaaggaaata
    12301 tagaaaatgt agaagacata cataaaatta tagagagttt aaaattagct tttgcagatt
    12361 ctaaaacata tgtaactgat atagagcata tgaaggtaaa gattcaggaa ttactaagcc
    12421 aagagtatgc caaaaaaaga agtttattaa ttgacaataa agaggctttg tatccaactg
    12481 caggagagcc atattgtggt ggtacagtat acctttgtac tgcagataag gatggaaata
    12541 tggtttcata tatacagagc aattacataa attttggttc aggaattgtg ataccaagaa
    12601 ctgggattgc tttacatagt agaggaaata attttaattt agaccctaaa caccacaatg
    12661 tagtaaaacc atttaaaaaa ccttatcata ctataatacc tggattttta ggtaaagaag
    12721 ataaagcaat aggtccattt ggtgtaatgg gagcttttat gcaaccacaa ggacatattc
    12781 aagtgttaac aaatatgatt gattttggat taaatccaca agaggcgcta gatgctccaa
    12841 gatggcagtg gataaaagga aaagaaatag aagttgaacc agagatgcca aagcatataa
    12901 tagattcatt aattgaaaag ggtcatgaaa taaaagtaat tcatgatact gttgacatgg
    12961 gacgaggtca aataatattt aaaacagaac aggaaagtta tatttgtggg acggaatcaa
    13021 gatgtgatgg tcatattgca gtttattaat attatcaact aaaatatata taataaattt
    13081 aaagagtata tgaaataata agtaaaggcg aaagtctaca atgactgacg cctttacaaa
    13141 acttaagcta tcatatgctg attttatata gattatgagc cttattcttg accagttttg
    13201 atttcattgt catcataact aatccagtca ctaaagctac caatataaat cttgtgaggt
    13261 atatccagtt ctctaagagc aagactgtta acacaagcag atatccctga accacaagat
    13321 aaaattactt catcataatt atttaaatct ttaaagaatt tttttaaaaa ttctatatct
    13381 ttaagtgagc cattttcaaa gtcacttttt attaaatcct tacaaaaata attttttgca
    13441 cttggtatat gaccagcttt tgagtaagca ggttcaacta aaccctggta tctctcatta
    13501 gcacgacaat ctattattac agtatctttt ttgtataatt tagacttaac atattccatt
    13561 ggaacaacta aatcattgtt tatatttggt ctaatttcct tacttgtaca acttggtata
    13621 ttcactttct cttccaattc tccaccttcc tttacgaaag atgttattcc cccatctagt
    13681 acatagacat ttttaagccc caaatgtttt aattggaaaa ataatctgca agctccattt
    13741 aaatctccat catcataagt tacaatcgta gtgtcattat caacacccat tttttctaat
    13801 ttttctttta gtattaaagg gtcttgtaaa ggatttttac caccatgttc ttttgtagga
    13861 gatgataaat ccttgtctat atctaagata aaactgcctt tgatgtgtcc ttttttataa
    13921 gaatcaatac cataagttct attgataaga tcaaatctgc aatctattac aactagatta
    13981 tcattttttt ctagttttga tataagttct tttgctgaaa taatgttttt caaagaatgt
    14041 acctcctgtg tttatattat ctttatttta atttatatta attattaact ttataaacta
    14101 atattattat aatttattac ataagtaaat aaatctttag aaattgtaaa aattttatat
    14161 aaaaattcaa ataattaatg aatattgaaa attttagata tataataaaa taagagtata
    14221 ttttatacaa tatgaaagct ggtattgcaa tagattaaag ccttatacac gtttagtttt
    14281 taaagaaatt agtgttatta tgaaaaccta agttaattta ttaaataaat aattgaataa
    14341 aaaaatttta ttatgtattt ataaaatttt tgttacaaat ttggcataat atagtatact
    14401 ttaagtgtgt attaggttaa atctataaca aattagacgt atgatataga cttagtgttt
    14461 attggcattt acaagaaatt tgttaatatc aactatttgt agtttgggca gttataatta
    14521 ctataggggg gatgtccaat acaaaacaat caaccaagaa ctaatattat attataaaga
    14581 gttatagttt tgtgtgttta tgtttttaat taaatttaaa gtgggaaaaa tatatttgtt
    14641 agaatggaga atagcgagat gagtaataaa atagttagta agagacaatt aacagatagt
    14701 atttatttaa tggaaataga ggcacctaga gttgcaaaat cttctcaacc aggtcaattt
    14761 ataataatta aaaatgatga aaaaggagag aggattcctc ttacaatagc tgactatgat
    14821 agagaaaaag gaacagtaac tattgtattc caaacagttg gtgcttcaac taaaaagtta
    14881 gcaatgtttg aagaaaacga ttttgtaatg gattttgtag ggccattagg acaagcaagt
    14941 gaatttatac atgaagatat agaagaatta agaaataaaa agatattatt tgtagctggt
    15001 ggagttggtt ctgctccagt ttatccacaa gttaaatggt ttaaagagca tggattagat
    15061 gtagatgtaa taattggtgc aagaactaaa gaattaatta tattagaaga tgatatgaaa
    15121 aaagtagcta aaaatgtata tgtatcaaca gatgatggta catatggatt taatggaaga
    15181 gttacagacc tattaaaaga tttagttgat aatcaaggta aaaaatacga ccaagcaata
    15241 gtaattggac caatgataat gatgaaattt atgtgccaat taactaaaga actaaatata
    15301 cctactatag taagtttaaa tacaataatg atagatggaa caggtatgtg tggtggttgt
    15361 agagttagtg ttggaaatga aactaagttt gcatgtgtag atggtcctga atttgatggt
    15421 catttagttg attttgatca agcaatgaga agacagtcta tgtacaagac tcaagaggga
    15481 agagctatgc taaaacttga agaaggcgat agtcatcatc atagtaattg tggatgtgga
    15541 ggtaacaaat aatggatgct aaaaaagtaa aagtaccagt tagagaacaa gaacctgctg
    15601 tgagagcaac aaattttgat gaagtatgct tagggtataa taaagaagaa gctatggcag
    15661 aagctaatag atgtttagct tgtaaaaaac caaaatgtgt gggtggatgt ccagtaggaa
    15721 tcgacatacc agggtttata acaaaaatta aagaagatga tatagaaggt gctgctaaag
    15781 taatagctaa gagcagttca ttaccagctg tttgtggtag agtatgccca caagaaagtc
    15841 aatgtgaagg tgtatgtata cttggaataa aatcagatgc tgtatcaata ggtaaattag
    15901 aaagatttgt agcagattgg tcaaaagaaa atgacataaa tttatctgat acagagccta
    15961 agaaaaatca aaaagtagca gtaataggaa gtggtccagc aggtctagct tgtgctggtg
    16021 atttagctaa aaaaggctat gatgtaacaa tctttgaagc aatgcatgag ccaggtggag
    16081 ttttaactta cggaatacct gagtttagac ttccaaaaca agctgttgtt caacctgaaa
    16141 tagacaatat aagaaaatta ggtgtaaaaa tagaaactaa tgtaattgtt ggtaaaacaa
    16201 ttacagtaga tgaacttata gaagatgaag gatttgaagc tatattcata ggttcaggag
    16261 ctggtcttcc aatgtttatg aatataccag gggaaaatgc aaatggagta ttttctgcaa
    16321 atgagttttt aactagagta aacttaatga aggcttatag agatgattat gatacaccta
    16381 ttagttctgg taaaaaagtt gctgtagtag gtggtggaaa tgttgctatg gacgctgcta
    16441 gaactgcatt aagattaggt tcagaatcat atatagttta tagaagaagt gaaaaagagc
    16501 ttccagcaag agctgaagaa gttcatcatg caaaagaaga aggcattata tttaatacat
    16561 taacaaatcc taaggaaatt ttagtagatg aaaatggata tgttaaaggt atggtttgta
    16621 taagaatgga attaggagag ccagatgatt ctggaagaag aagacctata gaaatagaag
    16681 gttctgaatt tgtacttgat gtagacacag ttataatgtc acttggaaca agcccaaatc
    16741 cactaatatc ttctacaaca aagagtcttg atataaataa gaagagatgc ttaataacag
    16801 atgaaaatgg tcagacttct aaagagggtg tatttgcagg tggagatgct gttactggag
    16861 cagcaacagt aatatctgca atgggtgctg gtaaaacagc agcatcatca atagatgaat
    16921 atttaaaagc aaaagttaat gcttaatttg taaattaaag agagggtgtc tcaaaatgaa
    16981 ctttttagtt catgaggcac tctttttgta caaaatcaaa tatgttttaa tcatttcaac
    17041 aatgaaaatt tcattcctgt agaaagtcta acttttaggt cttagtacaa tctctatttt
    17101 gatgtagcca cttttttaga tggtttaata atttatcagt tattattgta atatttgata
    17161 ctaagtaaca taactttgtc taactatgat aaaatagtta tacaataaag gtcttgtaag
    17221 gagtgaataa tgtgtggcta ataaaatcag atttgtcaaa tctaacatta aataatagaa
    17281 aaataaattg tgtaattaat ggtattttaa tatgaaaaaa agagaaaaag tatttgatgg
    17341 gctagttttt aagcatatat taatcttatt aatactatta gttttgattg atttaacaag
    17401 taccatcata tatgcaagta actctatgga aattacttct agaaatatga ttgaggcatc
    17461 aaaaagagaa cttgaaaact atttagaagt aaacatatct ttattaaaag ctcttagtca
    17521 agatgataga ttttctaatg gtgaaacatc actaattgaa aaggaaaaat tattaagtcc
    17581 atatcaaaag gaatataatc tttttatgat tggtataaca gatacaaaag gaaatgcttc
    17641 aagtacatat agggaaaatg ttaactcaat aaaagataag cctagtttta agaaagcaat
    17701 taaaacaaag caagtagtag tttcagatat tgaagtcagt aatgtaacag gtgacaaagt
    17761 atttatcata tatgtaccaa ttgtaaaaaa taatgagatg attgggacca tttttgcttc
    17821 tttttatttt caagatgtaa ataatttaat aagtagaagc aattttgatg attctattaa
    17881 atttctaatg atagataaag attatactat tatttctcat ccaaacaaaa aatatgtaaa
    17941 tgataaaagt aagatgcttg atttagaagg gaatattata ggaaccacta aaagtgaaat
    18001 cttaaaaaat ataaataaaa aatgtcaagg tgatttttta tcttgggata attggagatt
    18061 atataatgta aaatatacga acgtaaagtg gactaattgg actttagtat caaaatgtaa
    18121 tatatttaag aactttaaaa atctaatagt taattttatg ataaagttgt atttttatat
    18181 agtaatattt atgatattgt ggaaattaag taatgctaaa ttaatagaac aacttaaaaa
    18241 attggcttat tatgattctt taagtggaat aaaaaataaa gaaaagttta gaaaagattc
    18301 tatgtatatt ttaaagaatt attatcaaga taatttttac ttagtacaat tggatgtcaa
    18361 taaatttaaa tatataaatg agatgtttgg atatgctgaa gggaataaga tattaattca
    18421 tatatcacag gttttaaata ataatacaaa taaatatgaa atttgtgcta ggatggataa
    18481 tgaccatttt atattgttga ttgcttgtaa cactgaagat gaacttttaa atagattatc
    18541 taaaataaat aaagaaattt gtaacttaaa tactactaac tcatctaagt ataaaattgt
    18601 tatgtcaagt ggaatatata agattactaa aaaggatgat attaaaaaga ttgacttgtt
    18661 aattgataga gcaaatattg cagcaaaaag taaaaaggaa aaatatgaac attcatattc
    18721 attttttaat gaagatacaa gaaatcgatt gtacaaggaa aaacgattgg aagataatat
    18781 gaataaagct ttagaaaaag gtgaatttat agtatattat caacctaagt atagtttaga
    18841 tgatgtaaat gaaattgaag gagcagaagc cttgataaga tggaatagtc cagaatttgg
    18901 gtttatttca cctatagatt ttgtaccttt atttgaaaag aatggtttta ttgtaaatat
    18961 tgatatgttc gtgtttgaag aagtatgcaa aacattaaat aagtggataa ataaagggta
    19021 tactcctgta ccaatctctg taaatatgtc tagagttcat ttatataggg ataattttat
    19081 agaaaatata actgatttga taagtaaata caatatatct cctgagttta ttgaacttga
    19141 actaacagaa agtgttgtgt ttgataattt aaatatattg attgatataa tgaaaaagat
    19201 taaagagata ggattcctta tatcaatgga tgattttggt tcgggatatt catctttaaa
    19261 tctgttaaaa gacctttctt ttgatatttt aaaattagat agaggatttt taatcgaaac
    19321 aacagataca aaacgtggaa aaattattat ttctaagatt gtggaaatgg caaaagcgat
    19381 tgatattaaa gtaatctgtg agggcgtaga aacttatgaa caagtagagt tcttgaaaga
    19441 gataggttgt gataaggttc aaggatactt atttgctaaa cctatggtat tagatgaatt
    19501 tgaaaaacac ttaaacttta aatttgatta atcattaata attattagac tataagatac
    19561 cctaacaact tacttacaaa tatgtaagtt aattgttagg gtatttttat ggttaaagta
    19621 gtatattcac gatattatgg tattgtagta aaaataaaaa attatggaga atataaaatg
    19681 aacatattga gtattagaaa tatatcaaaa acatattgtg gaaatattcc atttaaagca
    19741 ttagataagg ttagtctaaa tatagaaaag ggagaatttg tgtctgttat gggaccatct
    19801 ggaagtggta aatctactct tttaaatata atatctacag ttgatagaca gagtgaaggt
    19861 gaggttgtat tagatggata tgatgtaagt aaattgaaag gagaaaaact tgctgaattt
    19921 agaaggaaac aacttggttt tgtatttcag gattttaatt tgattgacac tttaactgtt
    19981 ggcgaaaata ttatgttgcc acttacacta gagggggcaa gtatcaaaga tatgaatata
    20041 caaactaaaa gtatatctaa atttttagga atagataaaa ttttagatag aaaaacctat
    20101 gaaatttcag gaggtcaagc tcaaaggtgt gctattgcta gagctattat aaataaacct
    20161 gccatacttc ttgcagatga gccaactgga aatcttgatt caaaatctac tgatgatgtt
    20221 ttgaaattat ttactaggat aaacaaagaa caaaatgtaa caacacttat ggtaactcat
    20281 gaagcatata gtgcaagtta ttcagataga gtaattttta taaaagatgg ttgtatatat
    20341 acagaaataa aaaaatctga aagcaataat tctttctatt ctgatatact agctgttttg
    20401 tctcaaatag gaggtgtaag atagtggatt ttagaaagtt tgcttataat aatatagtta
    20461 gaaatttcag ggcatattta gcatattttt taagttctgt tttttctata atgatatttt
    20521 ttgtttttgc agtgtctatg ttccatccaa ttataacaaa atctggaatg cagagtggtt
    20581 ctactgcatt tatggctctt atgacttcag aattaataat attaggtttt agtctacttt
    20641 ttatattgta ctctttagga aatttcttga aatatagatt gaaagatttt ggagtattga
    20701 tgataattgg aatgagtaac agacaactga aaaaattgat attaattgaa aatttgataa
    20761 tagggttttt agcagtgatg ttaggaatat tacttggttt atcaatttca aaattgtttt
    20821 tattgtattt aagcaaactg ttttatatga atttaactga attttatttt ccagtaaaag
    20881 caatgctatt gactattgta tcatttatga ttttattttt gataacagga ccaatgagct
    20941 taaaattatt gagtaaaaag agcattttag agcttttagt aggtacaaaa aagcctaaaa
    21001 aagagataaa atcttcaaag ctatttggaa taattggtgt aatatgtctt atattaggat
    21061 atgctatgat actatttggc aataagttaa aaataaatgg aggtatgtat acaacagcac
    21121 tattaattac tttgggaata tttttatttt tttctcaatt tactattttg atattaaagt
    21181 atttaaaaaa taaagaaaaa ttttataaga acaaagtaaa tatgttactt ataagtaatt
    21241 tgatatataa attaaaggat aatacacgat tgttattttt aataacaata cttttatcgg
    21301 ctactttagt agcatttaca acaacttcaa cacttgtaag ttctcaagga gaagcttcta
    21361 aaaataattt cccaatggtt tactcatatt tttcagagca taataatgaa aaagaatatg
    21421 aagaactaca acaaattaga gaagcaatca aaggatatga ttataaggag ttaagttttc
    21481 ctgtacttaa atataatagg gaagtcttac taagtgtaaa gaattataac aaattatcaa
    21541 aggaattggg attagataaa attagttcaa agttagaaaa atatgaaggg attataattc
    21601 ctagtagcaa ttcacaagaa catataaatt ctttaaaaca attaaaaaat tatagtataa
    21661 aaaatttaaa tatagaagta aaaaaatcaa aaaataaaat aatttttcct acaggactgt
    21721 ttagtaaagt tgtagttata agtgatgact tatacaatga agtaaaaggt gaattttcaa
    21781 aaattaattt tcatggattt gattataaaa actggcaaag cagtgcaaag ataactgaaa
    21841 atttaaaaga aaaacatttt aatttggata gagaatataa caggtcatat tttttaacat
    21901 taccagatat gtatttagta gagttacaac aaagtaaaat tcttcaattt atgggtgttt
    21961 ttataggagt gatattattt atagcagttt ttagtttttt atacttcaga ttatatacag
    22021 acgagataga agataatgta aagtacaaaa aactatcaaa aataggtcta tcttttaaaa
    22081 atatgaataa gattgttagt atagagatag gtacattgtt ttttataccg tattttatag
    22141 caattataaa tagcataatt tctttactgt ttttaaatca agtattaaat aatagtttta
    22201 agttagaaaa tttgggtata ttactactga tatcatctat atattcactt tatttttact
    22261 tattaaaaaa aatttatact agaaaagttt ggttttttga ttaaagtggt atataataga
    22321 tatataaatt aatatttaaa aagtagttaa tattagggga gggcatttgc acctcccttg
    22381 taatatgtgg aaaattgaat attagaagaa ggaggagact tgatggaaaa tcaacaatta
    22441 ttaggaacag aacgaattag taaattacta ctaaaatatt ctataccagc tataataggt
    22501 atgttggtaa atagtttata taatgtagta gatagaattt ttattggaaa tataccaggg
    22561 gttggaccac ttgcaataac aggtcttggt gtaacaatgc caataatgac aataatactt
    22621 gcatttggga tgttgatagg tataggaact actactacca tatcaataaa acttgggcaa
    22681 ggtaaagtag aagaggcaag aaaacttata ggaaatgcaa tgacgttatc tgtaataaca
    22741 ggaattatca taatgatact tggaatatta tttgcaaata aaatacttac attgtttgga
    22801 gcaagtgaaa atactttaat atatgcaaaa tcatatatca atattatatt attaggtaca
    22861 gtagtaaatc ttctttcctt ttctttaaac cactcaataa gagctgatgg tagtcctaaa
    22921 atttcagcag gaataatgat agtaggatgt ttaactaata tagttttaga ctggatatta
    22981 atatttggat tcaatttggg aatacaagga gctgcaattg ctacagtaac ttctcaggct
    23041 cttacagcta ttttaactat agggtattat ataagtggaa aatcaaactt acgattcagt
    23101 aaatctaatc taaaattaga taaaaagcta ataaaagcag tgtttgcaat aggtatgtcg
    23161 ccatttgcta tgcaacttgc agcaagttta gttcaagtaa tatcaaatat tgcacttaaa
    23221 actcatggtg gagatttagc tataggagct atggctacta tttcttctat tgcaatggta
    23281 tttttgatgc ctatctttgg aataaatcaa ggagcgcaac ctattatagg tttcaattat
    23341 ggagctgaaa aatatgatag ggttaaaaaa gcatatttag gttcattagt agtagctact
    23401 ataattttat gtatgggtat ggtagtagtt atgcttttcc cagaagctat tataggtata
    23461 tttaataaag accctgaact tatgaatata tctgttaatg gattaagaat atacttactt
    23521 atgttgccaa ttgtaggctt atcagttaca ggaacaaact ttatacaatc tataggaaaa
    23581 gcaaaaatgg ctatgttatt gagcctttta agacaagtaa ttttattgat accagcagta
    23641 ttaattcttc ctacattctt aggtttacag ggtgtatgga cagctcaacc agtgtctgat
    23701 tttatagcta cagtaattac aggtatagtt gtatttagag aattaaaaag atatactcct
    23761 aaaactgaaa aattaaatga aaatgaaaga ctaaacgaga taactactga gtaaaaatat
    23821 aaattcagat aattgagcaa gaaattgcaa aaaatacgat tatatgataa aataaaaccg
    23881 ctgtcaagga taagagaaat tctaattatg gagtgatttt atggaattta caaagaaaag
    23941 caaattaaaa aatatgtatg taaacatgaa tgtagctaga atgttgtcta agataaatga
    24001 gtataagggt agacaactgc tttacaaaaa acaaccaaaa gaaattttag aaaacttaga
    24061 aaaaaaatct ttagtagatt gttctgaatc tacatacatt ggaaatcaaa gagatagtag
    24121 taattttaat ctagaaaagt tgataagtaa tgaagttaca cctagaagta gagaggaatt
    24181 gagtattgtt gaatacagag atgtggtaaa aactattaac agtgcttatg agagtattcc
    24241 catcagttca caaacgattc ttgagcttca tggatactta tataaatttt catctactag
    24301 aggaggaagt tataagtcag ataatgattt tattgaacac aatttaaaac ctagcgaatt
    24361 tataagtatt gattcaagtg gcaataaagt tgaaaaagct gtagaagaaa tatgtgaagc
    24421 ttataataca ttgatagagg aagatgaaat tgatatatta atattaattt ctgcatttgt
    24481 gttagatttc atattgatac atccattcaa agaaggtaat ataaaaatgg cgagagtact
    24541 tatcctattg ttactaaata aaaatgggta tgaagttgga agatatataa gtttaggaaa
    24601 gatatttgat gatagttcat atgaatatta tagtaattta aattatttga aagcctcaat
    24661 aggtagtgaa aaagcagata tgaatgcatg gattgagtat tttttagaga cgatattaac
    24721 tgcatatgag aagctggatg atagtttaaa tatatctgat aagaaaagac aaacaaaaac
    24781 tagtagaata gagaaaataa taaattctac ccttggatat tttacaaaag aagatataag
    24841 agatttatgt cctgacattc cagaacctac tataaataga gtttttaata atctaagaaa
    24901 acaagataag atagaagttg ttgcaagagg aagaagtgca aaatggaaga aaaaatatta
    24961 aaaaatgttt agataactaa aatggtatag tgttttacac tataccattt ttaatgtcat
    25021 tagtatgagt aataatttaa caacttaagc aatatcaatt ttatttattg attatttttg
    25081 aactgaaaaa tggcgttata tggtatacct cagtggtaat taattttgga tgagaagata
    25141 taatattaca gaatatatta ggagtatatg tagaaaaaat ataataaaag tgtgaggctt
    25201 agtaattaac aaattatgtg gcttcacact tttttataaa ataaagatac ttagcagaat
    25261 aatattttag ttgatatgtt tataagatgg tacttgtttg ggtaaaagta taaatagtaa
    25321 aaaagtagaa gtaatgtgta taaaaacgta agttacattc tgtaataata gttattttat
    25381 aattcaacaa aagaatagaa tgggtatatt tgtgaaataa taatataaaa taatcttagg
    25441 agtgagctta tgaagaaaaa attattatat ataaatgtaa attcaaaacc tgaagactta
    25501 tcttcaagta aaactgtagc aagaaaattt ataaataaat ttatggaaaa aaataaagat
    25561 tttgaggttg aagagataga cctttataaa gaacatatac caagacttga gtatcagtac
    25621 tttgaaaaaa gaaatagcat agttagtgaa gaaaatgcta aaaatttaga cgataaggat
    25681 agaaaagaac ttacaaagat tagaaatctt tgtgaccaat ttgtgaatgc aagtgtttat
    25741 gtaatagcag cacctatgtg gagtttatct tttccagcac cacttaaaga gtatatagat
    25801 tgtataattc aagatggaaa aactatatct tttgaaggca atgataaacc acaaggaatt
    25861 ttaaatgata ttgatagaag tatggtatat atacaatctt ctggtggaca cataccatgg
    25921 gtgttgaagc cagttatgaa taaagggtta aattatgtgg aaagtattat gaaatttata
    25981 ggaattaaaa aatttgatga attgttagta gatggaactg gaactagtga agaagaaaga
    26041 caagctgcta tagaaaaagc agctgaaaaa atagatggta taatagatgg gatgaaattt
    26101 taattataat attttattaa aaatataaag gaaaaacctc ttttaatgta gaaacttata
    26161 ttgaaggagg cgagaatcat gcgagaagaa aaaagtaatg aaaagtatga ttgttattgg
    26221 tgtaatcaag agaataattt ctgtgtagaa ataaaagata atatagtcat gatagatgat
    26281 ggcactggta cgttaaaaca agccgttttc atagggtata aacaaatcca aattaattta
    26341 aattgttcac attgtcaaaa cttaaataga ataaaattaa atttgtagaa ttttaaaatg
    26401 gaaattattg aaggaattaa aaatagaaag tgttaatatt tagactgaaa attatatttt
    26461 atacaataaa agtttattta aataacattg tattttaata tttattttca gtcttacttt
    26521 attaaaatta ttttttggtt atgtctggaa aatatctgtc tactaatttt tctgaaatat
    26581 tttttaattg gtcagccatt gaagtcagac ttaataaggt tatcaataaa tcatctttat
    26641 tttctggatt tatactaata ttttcaaaat tagactctat aaagtccggt atattctttc
    26701 tttgattttc ttttattaac atgaattttt cgtaacatga aactaaatct ttttcactga
    26761 aattatcctt ttcatacaca ccatgtaaga ttcttttaat ttcttgtatt gtaagtgtat
    26821 ttttcataga ataaataatt atcatctgta aaatttgttc tttagtatac ttttttccct
    26881 taactggttt gattaatccc tctttgctgt aattatttat catggtttta gtaagaattt
    26941 tatcactttc aaatctttta ttagcagaaa gcttattgtc aattagagaa ataatttgat
    27001 ccatatataa gtcaatagat ggaatatcgt ttgaagttat atctgcatta tttagtgttt
    27061 ctagtattat agtattaagt tcattattca tcatatgtta cctccataat atatataata
    27121 cactaaatta gaaagtaaaa caatattaag gcttgtaaaa aaaacataaa gtggtataat
    27181 taaatatata atatagtaat ggaaactata tttgtgaatc tgatttttaa aatacataat
    27241 tgtaggagga cgaaatgtat caattttttt taaagggtag agacccaata agcagtttaa
    27301 ctcattttat aggtgcttgt ttatctcttt tagcaactat aattttagtt tttcaatctg
    27361 ttacattaca ggaaacttct ctcttgatga tagtatctgt atcagtattt ggactttcac
    27421 taattgcttt atatagtgca agttcgtatt atcatttttt aaaggggaca ccagaacaag
    27481 aattgttttt tagaaaagta gaccatgcaa tgatttacgt attgattgct ggctcttata
    27541 caccaatatg tctgaatttt atggaaaaaa aagaaggcat aatatttgtt acagcaatat
    27601 ggatagttgc atttattggc ataataataa aaatattttg gatggatgca cctagatggt
    27661 tatctaccag tatatattta cttatggggt gggcaattgt ttttgatata aatgcattca
    27721 attcaattcc taaggattgc cttagactat taattatgga aggtgtatct tactctatag
    27781 gtgcgattat ttatataatt aaaaagccta atataagtcc tgagtttgga tttcatgaaa
    27841 tatttcatat ttttattatg ataggttctt tatttcactt tttagcagtt ttattgtatg
    27901 ttttatagtt ttaaaagatt tgattaattg atactaaaat tctacaatga ataaaatgga
    27961 actgccttat atagattata tcttagacaa taagacagtt ccttattata aatattaaat
    28021 tctacttata ataaaatttt gataaaaata gtccattcaa aatgcctatt ccataattcc
    28081 tttaatgtac ttttcattta cgacatatag tttgaattta tgtactataa ttatatcctc
    28141 taaattctct gaaacactaa caattctgac acatttgttt ctaatttcta caggtaaatc
    28201 taaatcattt gttaaattca catagtcatc atatttatac ataaaatcat ccctttacat
    28261 taagatatac ttattatact atattttaat aagttttttt aaattattac aatttttccc
    28321 gaaatttcat tttttataca taaaatttcc aaattaggta aagattaaat ttt
//
LOCUS       DAEORM030000047        28161 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.047, whole genome shotgun sequence.
ACCESSION   DAEORM030000047 DAEORM030000000
VERSION     DAEORM030000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 28161)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28161)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 28161)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28161
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.047"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            complement(86..601)
                     /locus_tag="KRH23_002716"
     CDS             complement(86..601)
                     /locus_tag="KRH23_002716"
                     /EC_number="3.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016790 - thiolester hydrolase activity
                     [Evidence IEA];
                     GO_function: GO:0016836 - hydro-lyase activity [Evidence
                     IEA];
                     GO_function: GO:0047617 - fatty acyl-CoA hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HHS5225994.1"
                     /translation="MDFLAKYKVLKKQNSSKSCLVCGTQNELGLKADFYELENGELVS
                     ICNTKDWHQSYPGRVHGGMSAAILDETIGRAVSINDDQIWGVTVSLELKYKKPVPTDA
                     TIKVVGRITKENRKLFEGTGEIILPNGDIAVTATGKYMKMPIGQIAEGDFSNEEWFFE
                     ESKEKVEYIEL"
     gene            complement(964..2034)
                     /gene="leuB"
                     /locus_tag="KRH23_002717"
     CDS             complement(964..2034)
                     /gene="leuB"
                     /locus_tag="KRH23_002717"
                     /EC_number="1.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003862 - 3-isopropylmalate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0009098 - L-leucine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="HHS5225995.1"
                     /translation="MNCNIAVIKGDGVGPEIIDEGIKVLNKICCKFNHRFDCEYVLAG
                     GCAIDETGEPLPNKTVETCRKNEAVLLGAVGGPKWDKCKGDKRPESGLLKLRESLGLF
                     ANLRPATMYESIKEASPLRTDIVEKGIDFVVVRELTGGIYFGERGRKIIDGIENAYDV
                     EIYNENEIRRIGKRAFEIARNRNKKLISVDKANVLESSRLWRSIMEDLAKEFEDVELS
                     HMYVDNAAMQVVKDPSQFDVIVTNNIFGDIISDEASMITGSIGMLPSASLREDSFGMY
                     EPIHGSAPDIAGKDIVNPIATILSVSMMLRHSFNLEEEAKCIEDAVQSVLNKGYRTID
                     IYNGVGNVVGTRAMGELIVNEI"
     gene            complement(2041..2532)
                     /gene="leuD"
                     /locus_tag="KRH23_002718"
     CDS             complement(2041..2532)
                     /gene="leuD"
                     /locus_tag="KRH23_002718"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009316 - 3-isopropylmalate dehydratase
                     complex [Evidence IEA];
                     GO_function: GO:0003861 - 3-isopropylmalate dehydratase
                     activity [Evidence IEA];
                     GO_function: GO:0016836 - hydro-lyase activity [Evidence
                     IEA];
                     GO_process: GO:0009098 - L-leucine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HHS5225996.1"
                     /translation="MIANGSVFKFGDNIDTDVIIPARYLNIADYKELATHCMEDIDDK
                     FISKVKKGDIIVATKNFGCGSSREHAPIVIKESGVSCVIASTFARIFFRNSINIGLPI
                     LECEEAANNIDEGDNIEVDFSTGVIKNITKGKEYKAEPFPEFMQNIILNEGLINSIKA
                     NRG"
     gene            complement(2547..3824)
                     /gene="leuC"
                     /locus_tag="KRH23_002719"
     CDS             complement(2547..3824)
                     /gene="leuC"
                     /locus_tag="KRH23_002719"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009316 - 3-isopropylmalate dehydratase
                     complex [Evidence IEA];
                     GO_function: GO:0003861 - 3-isopropylmalate dehydratase
                     activity [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0009098 - L-leucine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase large subunit"
                     /protein_id="HHS5225997.1"
                     /translation="MGMTMTQKILAKHAKLNEVKKGQLIEADLDVVLGNDITSPVAIR
                     EFEKLGIEDVYDKTKVVMVLDHFTPNKDIKSAEQCKFTRSFAKSKGVVNFFDVGDMGI
                     EHVLLPEKGIVTAGDVIIGADSHTCTYGALGAFSTGVGSTDMGAGMATGKCWFKVPGA
                     IKFVLKNKPNKWISGKDIILHIIGEIGVDGALYKSMEFCGDGVEYLSMDDRFTICNMA
                     IEAGAKNGIFPVDDKTMEYINSHKCSTMTKDVNIYEADEDAVYDEVYEIDLAELKETV
                     AFPHLPENTRTVDEIDKDIKIDQVVIGSCTNGRISDLEVVAEIMKGKKVADGVRVMIF
                     PGTQKVYLEAIEKGYITTFIEAGAAVSTPTCGPCLGGHMGILAAGEKSISTTNRNFVG
                     RMGHVDSEVYLASPAVAAASAITGKISKPSEII"
     gene            complement(3781..5523)
                     /gene="leuA"
                     /locus_tag="KRH23_002720"
     CDS             complement(3781..5523)
                     /gene="leuA"
                     /locus_tag="KRH23_002720"
                     /EC_number="2.3.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003852 - 2-isopropylmalate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009098 - L-leucine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HHS5225998.1"
                     /translation="MKCGKYKKYDKMQIVNRKWPDNEIFKAPIWCSVDLRDGNQSLPT
                     PMSVNEKVRMFKMLIDTGFKEIEVGFPSASNTEYTFLRKLIDENMIPDDVTIQVLTQS
                     RAHLIEKTFESIRGCKKAIIHLYNSTSVLQRDVVFNMSKQEIIDIAVEGAKLFNEEVK
                     KYPETEFTFEYSPESFTGTEMDYALEICEAVIDVWKPTPQKKVIINLPSTVEMATPNV
                     YADQIEWFCKNISCRDSIILSLHTHNDRGTCTAASELGLLAGADRLEGTLFGNGERTG
                     NMDIVNVGLNLYTQGIDPELDFSNIDKIIGIYEDCTKLMVHDRHPYAGNLVHCAFSGS
                     HQDAIRKGMIAMKNRDNDYWEVPYLPIDPHDIGREYKEIIRINSQSGKGGAVYIMETD
                     YGFMIPKNMHSDFGNVVKMESDRIGEELSSEAIFNLFKKEYIEVESPYKVKKYKIKSM
                     DELNYENDDSNDTNMIEMTARISYMGNEQRIVGIGNGPVDSFNNALKQCGMKDYKFRY
                     YWEHALEEGSHSRGVAYVGIEHNNEVYFGVSISENINTAAINALMNAINKSYIEEEIK
                     NGDDYDAENISQTC"
     misc_binding    complement(5647..5893)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(6041..6487)
                     /locus_tag="KRH23_002721"
     CDS             complement(6041..6487)
                     /locus_tag="KRH23_002721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5225999.1"
                     /translation="MSKNKFIYMNYYDNGYFKKGMTIYMVLALIILATIFIYSTTILY
                     ILCIITAVFLFKQGRDFSNKYEGKVYITLDNHSILINNQCIFSIKSKQSQKFNYKIIE
                     KIEVVKNILNIYTDESNYKIRLRALSSEDEKKLLNIIDEKMKKFKA"
     gene            complement(6508..7227)
                     /locus_tag="KRH23_002722"
     CDS             complement(6508..7227)
                     /locus_tag="KRH23_002722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase"
                     /protein_id="HHS5226000.1"
                     /translation="MKKSIMDVHCHTLISGHAHSTFKENVEEASKKNIKYLGISDHGP
                     NMPGGPHPFYFYNLHLLPREVQGVKILRGIEGNIMDYNGNLDVQEDMLQHLDYIIASL
                     HRPCIASGTKEENTNAILKVMDKPKVKIIGHPDDSRYPLDYEPIVKKAKDKNILLEIN
                     NSSLSSNSHRTGTWENVSHMLTLCKTYGARVILGTDSHICYSIGEFENAEKVLEAVDF
                     PDELVINYHEDEIIEFFDINF"
     gene            complement(7345..8619)
                     /locus_tag="KRH23_002723"
     CDS             complement(7345..8619)
                     /locus_tag="KRH23_002723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HHS5226001.1"
                     /translation="MFIMENDLTMQELLDQQEQVFSKVKVGELTTGKITAVRNDEVQL
                     GLDYGFDGIIPISELNIEKNQYIEDIYHIGDEITAVITKVSQKDGTITLSKLQLDKRN
                     DFAELQKAYDEHRIITVNVEKNIDKGVFANYNTYTFFIPISQLDTKFITDTSKFVGLN
                     LEVYIKELDVRKNRLVASHRDVLQERINKEREERRAQIKAEKEAERARIKQEREEEKA
                     RIKAAKEDLFNSLEVGQKRDGKVTKIMPYGAFVDIGGIEGLAHINNLAWTRVESVEDV
                     VSEGQEVEVYVLDVNKETKKIALALKDINNDPWDLIAKEVQIDDVVNAKVLRIIEKGA
                     FVQIKEGVDAYLPISELSDTRVAKVTNVVNIGDEVKVKILDFKPKTKRMLVSIKEATR
                     EPEEDITEYLEVEESLGSIGELFKDKFKDLEV"
     gene            complement(8819..10186)
                     /locus_tag="KRH23_002724"
     CDS             complement(8819..10186)
                     /locus_tag="KRH23_002724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA];
                     GO_function: GO:0042910 - xenobiotic transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006855 - xenobiotic transmembrane
                     transport [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HHS5226002.1"
                     /translation="MENSNTNLGSESVGKLLFKLATPAIIAQIVNVLYNIVDRIFIGR
                     MENGEVAMAGVGVAFPIIIIITACSYLIGMGGGPLAAIKMGEQNNDEAEKIMSNSFSV
                     LVILAILLTIGFKIGKEPLLWMFGASESTIGYSMDYLNIYLIGTVFVQISMGMNTFIN
                     TQGFATTGMMTVAIGALINIILDPIFIFGFNMGVKGAALATIIAQGVSAIWVLMFLFG
                     KKSILKIKKKYMIPKASIILPVLGLGISPFIMQSTESLVLIALNSKLQMYGGDLAVGS
                     MAIMSSIMQILMLPNMGVTQGAQPIISYNYGSGQLDRVKKTFKLCLLSCFTYSTILWL
                     LLMIFPAFFVSIFNKNPQLLSMTSWSIKIYFAGAFMFGIQIACQQTFLALGKATISLV
                     LALLRKIVLLIPLIFILPTFFNEKLFAVILAEPVADITAATITAISFFIFYKCFLSKP
                     KAIKE"
     gene            complement(10436..10873)
                     /locus_tag="KRH23_002725"
     CDS             complement(10436..10873)
                     /locus_tag="KRH23_002725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="COG2426 family protein"
                     /protein_id="HHS5226003.1"
                     /translation="MGYLHILILSMVPVTELRGAIPIGIAMGLNPIWVYVFSVIGSTL
                     VSIPLILTFRHVLQFLRGKKLFKGIADVIDRKINSRMKKLKSVSIIGIILFVGIPLPT
                     TGTWTASAIASILKMRIKDAFMGVFLGNLLSGVIVSALSLHII"
     gene            complement(10905..11534)
                     /locus_tag="KRH23_002726"
     CDS             complement(10905..11534)
                     /locus_tag="KRH23_002726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family hydrolase"
                     /protein_id="HHS5226004.1"
                     /translation="MKKSVLLLDVDYTVINTDSMIDFFIYSLKNKTFKTIIKLPYIIF
                     ILFMYLIRMIPLKKAKEAIFYPIVDFSEEDLKKFFDDCIMKKINESMKKVIYKNKEED
                     NVIIMITASPYAYMKYFKYYGLADEVIGTEFFYENSRYKNQFIGENCKGIEKVKRIKA
                     VLGKLGIEIDYENSYAYSDSKSDLPMLSLTKNAFLVSKKDGEVIEQINS"
     gene            complement(11568..12455)
                     /locus_tag="KRH23_002727"
     CDS             complement(11568..12455)
                     /locus_tag="KRH23_002727"
                     /EC_number="2.4.2.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="decaprenyl-phosphate phosphoribosyltransferase"
                     /protein_id="HHS5226005.1"
                     /translation="MKQTNTSIRLLTKISDYIKLMRIKQYIKNFFVFSAIIFSNNILN
                     INLFLNTFIAFVCFCLMSSSVYALNDAIDMDKDKKHPKKCNRPVASGRISKKSANILF
                     VVLALISVCLSTVVSFNLSIILSLYLINNILYSLKLKNIILLDVFSISLGFILRVYAG
                     CVAISVSLSNWIILCTFFLSLYLALGKRKKEIETLRDDAVEHRKILEDYDIENLNQMM
                     IVILSSTIVCYALYSTSNPEKPHMIFTTIFVVYGVLRYNYIINTTNENNPTDIVLKDN
                     ALKINVILWIITCLIILIF"
     gene            complement(12484..13704)
                     /locus_tag="KRH23_002728"
     CDS             complement(12484..13704)
                     /locus_tag="KRH23_002728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6080 domain-containing protein"
                     /protein_id="HHS5226006.1"
                     /translation="MSKILKYKNEMFLFILVVITYLIITKIFFSKTTIFYDLNNTYDV
                     LLDTDTGVLFNLNVFAISQDNSKHILFSAIISIFAYPIYLFCTSIANPGTTDFNSAYG
                     FGLICLQIITSAMSITLVFNHIKKIKMQRLTLILLTMIMIFSFPQLFMTLNVERFIYS
                     QFSLIFFIVIANKMKGKNSYLVELAAIPLFGITISNIYLYFFNMIFEFKLKIGKMLKH
                     LITFILMAYICVVSTKSYESFMNLGNVIQYDTKFISGEPILEKIAMIIERLLYSVFYF
                     PGASIKKGLFLQNGEVATIPVILTLLALCFCVLSVIENSEKRVPKLCMGIIIFNLTLH
                     GIVGYNLVNSSIMAINFSFAVIILLAYFTKALRKNEKNMYNIFLSLLLVTIVISNVNG
                     FIEILNIGIKSYPV"
     gene            complement(14106..15248)
                     /locus_tag="KRH23_002729"
     CDS             complement(14106..15248)
                     /locus_tag="KRH23_002729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HHS5226007.1"
                     /translation="MRYVEYGKTGKMVSVVGYGGLRFDLEKSNQENADLVKYAYEKGI
                     NYFDTAPGYCDDRSEDIFGLAFRQMIKEGKTDFYVSTKEKPKACDTSEKAIEAVKKSI
                     ERLGVSKINFYHVWNIRKMEHYELAMRPGGQYEGLLKCKEEGLIDHIVFSSHQPGDEV
                     IDILSENKFEGVTMGINILNFPYRLKGAKYAVDNGYGVVAMNPLSGGTIPKYNKELSF
                     LSKDGESTIESALRFNIGISQISISLIGFNKKQDIDDACKIADENRIYSDEDIHDIET
                     RLNKNMNEICTGCGYCKVCPKGINTPAYMLFYNEKQMFKKSDEEMTKLVYGLGHWNYT
                     MNSKAKAKECISCGKCEVECTQHLPIIDRLKEIKKWEEDGANSVKV"
     gene            complement(15389..16255)
                     /locus_tag="KRH23_002730"
     CDS             complement(15389..16255)
                     /locus_tag="KRH23_002730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HHS5226008.1"
                     /translation="MDNYKKVKQVLWIILFANFAVALLKIIIGNQIKSYSMTADGFHS
                     LSDGASNIVGLIGIFFASKPKDKNHPYGHKKFEIITSLFISGMLFVIAIKIILSAVLR
                     IANPVVPAITIESLIALIITLFINIFVCMYEYRIGTKLNSYVLISDSLHTRSDIFVSL
                     GVLVTLVGVKLGFPVIIESIVPIIISAFIIYSAYGIFRPSIGILVDRVAVDEDYIKEI
                     VFEFNEVRDVHNIRSRGSKSSIYIDMHVMVDPFISVEQSHDLTHKIEKQIQEEINENA
                     QVIVHIEPFYSF"
     gene            complement(16589..18136)
                     /locus_tag="KRH23_002731"
     CDS             complement(16589..18136)
                     /locus_tag="KRH23_002731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine ABC transporter
                     substrate-binding protein"
                     /protein_id="HHS5226009.1"
                     /translation="MANFFNFILLQKDKIIELLIQHMSLTVTSILIAIIVGVPLGIII
                     SRISSLRKFVLGFVNLVQAVPSMALLGLLVPILGIGSKPAIFMVVVYSLLPIVKNTYI
                     GITSIDPVVLESAKGIGLTRNQTLFKIQFPLALPIIMGGVRISAVTAVGLMTLAAFIG
                     AGGLGYLVFSGVQTVNNNMILAGAIPSCIIALLVDYLFSKIEVAVTPKGLNPKAPKKN
                     YIALKVISVVVVVSMLFVVFSSSFSSKKDTITIGSKDYTEQLILGNVYAELVEKNTNL
                     KVKKNLNLGGSSVAFNAIKSGELDMYVDYTGTLLVNVMKHAPIKDADEAYNVVKDTME
                     KENQLTLLDPLGFNNTYTLAMMPETAEKYGINTISDLTKYGKEFTFSPTLEFENREDG
                     LVGLSRDYGLKFKDVKAMNGSLRYTALDNNESQVIDAFLTDGLIKKFNLKILEDDKNF
                     FVPYYAAPLVREDTLKKYPELEKVMNMLSGKINEETMRELNYQVDELGKSPEEVAHSF
                     LVKEGLV"
     gene            complement(18129..19265)
                     /locus_tag="KRH23_002732"
     CDS             complement(18129..19265)
                     /locus_tag="KRH23_002732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHS5226010.1"
                     /translation="MIEIRNVTKKIGNNVILDDISLAVETGTLVVLIGSSGCGKTTTL
                     KLINKLIKPTSGEIYINGKPISQENEIELRRKIGYVIQNTGLFPHLTIKENIELIPRL
                     KKEKSVEEIEKRTLQLLEMVGLDSDEFLNKYPSELSGGQQQRIGVARAIATDAEIILM
                     DEPFSALDPITRTSLQEQLFSLQDELKKTIIFVTHDMDEALKIADKICIMKDGRIAQY
                     DTPENILRKPANDFVKDFIGEDRVWDNPEYIKARDIMIKNPIAVNSTRTVTQGIEIMR
                     TSKVDSLLIIDRAKTLKGIVTVKDMKDIDDKSILLADIMSSEPLHVNEGDNLVEILNV
                     MNRNSVGYIPVISDENKLVGLITRSSLLSVLSEQFLEMEVSVLG"
     gene            complement(19528..20625)
                     /gene="dinB"
                     /locus_tag="KRH23_002733"
     CDS             complement(19528..20625)
                     /gene="dinB"
                     /locus_tag="KRH23_002733"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HHS5226011.1"
                     /translation="MKHYRKIIHIDMDAFYASIEQRDNKKLKGRPVIVGGNPQSRGVV
                     ATCSYEARKFGIHSAMPSAVAYNRCPYAVFVRPRFDVYKSVSEQIRDIFYRYTDLVEP
                     LSLDEAYLDVTKNKKNIDSSIEIAKQIKKDIFREVGLTSSAGVSYNKFLAKIASDLRK
                     PNGLTVITEENAQDFLDKLPVNKFFGVGKVTSNTLKNLGIKTGYDLRCLNLFELENIF
                     KKRGYELYKFARGIDDRPVEPNRVRKSVGAETTLSHNLDIDEEETRNILDELCEEVCH
                     RLKNSEKFGKTLTLKIKYEDFTKITRSLSLEHYIDEYNDIRSGVDNLLRNVEVNGKQI
                     RLLGVTISNLSDKKETYKDITLFEYMDSIQM"
     gene            complement(21015..22520)
                     /locus_tag="KRH23_002734"
     CDS             complement(21015..22520)
                     /locus_tag="KRH23_002734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HHS5226012.1"
                     /translation="MKVGFDHKKYLEEQSKYILERVNNFDKLYLEFGGKLMGDLHAKR
                     VLPGFDENAKIKVLQHMKEKVEVVICVYAGDIERNKIRGDFGITYDMEVLRLIDDLRG
                     YELDVNSVVITRFEGQPATTVFINKLERRGIKVYKHYPTKGYPSDVETIVSDEGYGAN
                     EYIETTKPIVVVTAPGPNSGKLGTCLSQLYHENKRGNVVGYSKFETFPVWNVPVKHPL
                     NIAYEAATVDLKDVNMIDSFHLETYGEMSVNYNRDLELFPVLKKIIEKITGKESIFQS
                     PTDMGVNRVGFGIIDDEVIRKASIEEIIRRYFKTACEYKKGQVDKGAYDRMKMIMEEL
                     NLKPEDRNVVLPARNYSNKLKESADKNDTCPVVALELEDGTILTGKGSDLMNGTAAVV
                     LNAIKHLANISDDMHLISPVILEPIINLKTKTLASRNVSLSCQEVLTALSICAVTNPT
                     AQFAMEKLALLKGCQAHSTTILNRDDEQTFRKLGIDVTCDPEYPSQNLYYS"
     gene            complement(22781..23131)
                     /locus_tag="KRH23_002735"
     CDS             complement(22781..23131)
                     /locus_tag="KRH23_002735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6483 family protein"
                     /protein_id="HHS5226013.1"
                     /translation="MAIVDKIFNEIKLMVARLLLGKKYSEYEEKDLVYNTEEEVILIT
                     LKRLVFQGNVNEAEEILFDKAKSVNSENMQYIAIEFYTMLMEKTDEELEAMNFSKQEV
                     YQGIEDIRKVLNLE"
     gene            complement(23354..23545)
                     /locus_tag="KRH23_002736"
     CDS             complement(23354..23545)
                     /locus_tag="KRH23_002736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226014.1"
                     /translation="MLDRFFGEGGFGGCAWWIIILFFLFLAFQDCWAEMDLCAWIPFL
                     ILLLILCECGDVFDGGCGC"
     gene            complement(23663..24589)
                     /gene="blaAHM"
                     /locus_tag="KRH23_002737"
     CDS             complement(23663..24589)
                     /gene="blaAHM"
                     /locus_tag="KRH23_002737"
                     /EC_number="3.5.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AHM family subclass B3-like
                     metallo-beta-lactamase"
                     /protein_id="HHS5226015.1"
                     /translation="MRKIVLKDILFLVTTLSIIVILLLVTNITTNSKIKSTSESYLKS
                     DKNSVRQNGIQRSTKSSTKNTAFKTTILSTGKSDCILVEIGNKVIMIDTGEDKNGKQI
                     VDRLKEKGINTLDYLILTHLDKDHIGGVDSVLSSIKVKNIIQANYKKDSKQYDEYIDS
                     LKKADIEPVLLKDNMNIVINSAEINIHPASKSKYESSNDYSIITNISYGAHKFLFAGD
                     AEEERLSEFINGNTLKYDFVKMPHHGRYDKLTETFLESISPQYAVITCSEKKEPEEGV
                     LKILERLNIKTFLTSNGEVVINSDGKTLSVNQ"
     gene            complement(24723..26219)
                     /locus_tag="KRH23_002738"
     CDS             complement(24723..26219)
                     /locus_tag="KRH23_002738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HHS5226016.1"
                     /translation="MFEFETQLKRLKHEVLTAVARLSIEENLTKENIEKIPYEIIKGE
                     KARYRCCVYKEREVVLERAQLALSLTPNSKYGDINPDSVSLDTDEQIIYIVEAACDRC
                     PINEFTVTELCRGCLAHRCKEACKFGAISYINGRAYINHDLCKACGMCKSSCQYDAIS
                     EIVRPCKSVCPTGALDFNRNTMKAMIHEDNCINCGACMSACPFGAISDKSLIAPVAKK
                     LAKKENMYAIVAPAITGQIDSNITYGQLKNAIKSLGFVDMIEASCGADAVTVHESNEL
                     IERIKSGDNYMTNSCCPGFFKYIEKMFPDEKDRISSTVSPMVATGRLVKKIDSDAKVV
                     FIGPCTAKKSEATEKSLKDSVDYVLTFEELMALFEAFNIDLSKCSNEDINDGSIFGRG
                     FGASGGLAKSVQNYIAEKGLSFDFEPIKVSGPRQIKKTMTMAKLGRLEGNFIEGMMCE
                     EGCINGAGKFLSGVKAKNTFDRKNGQSTKKSVLSNDKIKEFEDVNLER"
     gene            complement(26499..27989)
                     /locus_tag="KRH23_002739"
     CDS             complement(26499..27989)
                     /locus_tag="KRH23_002739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HHS5226017.1"
                     /translation="MFQFETQIHKLRHDVLTAIARLGKEDNLTREAMDNIQYEIIKGE
                     KPTYRCCVYKERAIISERVNVSMGLQPGQDKIDLDTMDIEEDEQIIYILEAACDSCPI
                     NEFTVTDICRGCLAHRCKEACKFGAITHVGGMAYINHELCKACGMCKKACQYDAISEV
                     VRPCKSVCPTNALGFDRENMKAMIHEDKCLNCGACMSACPFGAISDKSLIAPVARKLV
                     QKEKMYAVVAPAITGQVEANVTYGQIKNAIKSLGFVDVLEAACGADAVTVHESLEFAE
                     RMEKGEAFMTNSCCPGFVGYIEKTYPNHVGKISSTVSPMIASGRFIKSHEPDAKVVFI
                     GPCTAKKSEAAKKELKGAVDYVLTFEEIMALFEAFDIDLAKCSNEDIDDASIFGRGFG
                     AAGGLTKAIENYLAEKGIGVNFEPVKISGSREIKKTMTMANLGKLEGNFIEGMMCEGG
                     CINGSGKFLSGAKVKATFDRKNSQSTKKSVLANTKIKDFSNINLEK"
BASE COUNT         9174 a         5153 c         2898 g        10936 t
ORIGIN      
        1 tttatcttgt atttttattg tatttttaaa ttttattttt tctaaatata aaatttatgt
       61 tttaaaatgt aaaattttta tttaatcaaa gttcaatata ttccactttt tctttcgatt
      121 cttcaaaaaa ccattcttca ttagaaaaat caccttctgc aatttgtcca ataggcattt
      181 tcatatactt tccagttgct gtcactgcta tatctccatt tggtagaatt atttctcctg
      241 taccttcaaa taattttctg ttttctttag ttattcttcc aacaactttt atagtagcat
      301 ctgttggtac tggtttctta tatttcaact ctaaagatac tgttactccc catatttggt
      361 catcatttat acttacagct cttccaatag tctcatccaa tattgcagca gacatacctc
      421 catgaactct cccaggataa ctttgatgcc aatcctttgt attacaaatt gatacaagct
      481 ctccattttc aagttcataa aaatctgctt taagtcctag ctcattttgt gttccacaaa
      541 ctaaacaaga tttactacta ttttgcttct tcaaaacttt atactttgcc aaaaaatcca
      601 tctcctaacc gacattagta gtcgcttaat attaaataat tctaaaatat attatataat
      661 attaataaaa tccctgcaaa cttctaataa taaaaatagg ctacttcaat atgataagtt
      721 taatttaaag tattattttc caaaaaataa ctttatcaaa atagaaactc aaagtagata
      781 taagcctctt tttcgttatt aaaatagtaa aaatatattt tacttaatat aaaaaagagt
      841 gtctcattaa ctaataaagt ttattttgag acacccctca taaaacaaat tatactacaa
      901 tagattttta ctaattctac aagttatata tttaaattat attattcaaa ttaaactata
      961 attctaaatt tcatttacta ttaattcgcc cattgctctt gttcctacaa catttcccac
     1021 accattatag atatcaatag ttctataacc tttattgagt acactttgta cagcatcttc
     1081 aatacactta gcttcttctt ctaagttaaa actatgtctt aacatcatgc ttacagatag
     1141 aatagtcgca attggattta caatatcttt tccagctata tcaggtgcac ttccatgtat
     1201 tggttcatac ataccaaaac tatcttctct aagtgatgct gatggtaaca tacctataga
     1261 acccgtaatc atagatgctt catcagatat tatatctcca aatatattat tagtcactat
     1321 tacatcaaat tggctagggt cttttacaac ttgcatagca gcattatcaa catacatatg
     1381 tgacagttct acatcttcaa actctttagc taagtcttcc attatacttc tccaaagtct
     1441 tgaactctca agcacatttg ccttatctac acttataagt tttttatttc tatttctggc
     1501 tatttcaaaa gctctcttac caattcttct tatttcattt tcgttatata tttctacatc
     1561 ataagcattt tcgataccat caatgatttt tcttccacgt tctccaaaat aaatgccccc
     1621 tgttaattcc cttacaacaa caaaatcaat gcctttctca actatatccg ttctaagtgg
     1681 tgaagcttct tttatacttt catacattgt agctggtctt aaatttgcaa ataaacccaa
     1741 tgactctctt aattttaaaa gaccagactc tggtctttta tctcccttac atttatccca
     1801 ctttggtcct ccaacagcac caagcaatac agcttcgttt tttcgacaag tttcaacagt
     1861 tttattaggt agaggttctc cagtttcatc aatcgcgcat cctccagcta atacatattc
     1921 acaatcgaat ctatgattaa atttacaaca aattttattt agaaccttta taccttcatc
     1981 tataatttcc ggtccaacac catcaccttt tatgactgct atattacaat tcatacttca
     2041 ctacccccta tttgctttta ttgagttaat taagccttca tttaatataa tattttgcat
     2101 aaactcagga aatggttctg ctttatattc ttttcctttt gttatatttt ttatcacacc
     2161 tgtagaaaaa tctacttcta tattatcccc ttcatctatg ttattggcag cttcttcaca
     2221 ttcaagtata ggaagcccta tatttataga gtttctaaaa aatattctag caaaagtaga
     2281 agcaatcaca caggatactc cactttcttt tattacaatt ggtgcatgtt ctcttgatga
     2341 accacaacca aagtttttag ttgcaactat aatatctcct ttttttacct tagaaataaa
     2401 tttatcatca atatcctcca tacaatgcgt tgctagttct ttataatcag ctatatttaa
     2461 atatctagct ggtattatta catctgtatc tatattgtca ccgaatttaa aaacacttcc
     2521 attggcaatc ataaatttta cctcccttaa attatttctg atggttttga tatttttcca
     2581 gttatagctg atgctgctgc tacagctggg cttgcaagat acacctctga atcaacatgc
     2641 cccattcttc ctacgaaatt cctatttgtt gttgaaatgg atttttctcc tgctgcaagt
     2701 atacccatat gtccccctag acatggacca caagttggtg tagaaactgc tgctcctgcc
     2761 tctataaaag tggtaatata ccctttttct atagcttcaa gatatacttt ttgagttcca
     2821 ggaaatatca taactctaac tccatctgct acttttttgc ctttcattat ctcagctact
     2881 acttcaaggt ctgatattct tccatttgta caagagccta ttacaacttg gtctatcttt
     2941 atatccttat ctatctcatc tactgttcta gtattttcag gaagatgagg aaaggctact
     3001 gtttctttta gttcggctaa atctatttcg tatacttcat catagactgc atcttcatct
     3061 gcttcatata tatttacatc ttttgtcata gttgaacact tatgtgaatt tatatattcc
     3121 atagtcttat cgtctactgg aaaaattcca ttttttgctc ctgcttctat tgccatatta
     3181 caaatagtaa atctatcatc catagataag tattctactc catctccaca aaattccatt
     3241 gacttgtaaa gtgctccatc aacacctatc tcccctatta tatgaagtat tatatcttta
     3301 ccacttatcc atttatttgg tttatttttc aaaacaaatt ttattgctcc aggaacctta
     3361 aaccaacatt ttcctgtagc catacctgct cccatatcag ttgaacctac accagtagaa
     3421 aatgctccta atgctccata tgtgcaagta tgagagtcag cacctataat tacatctcca
     3481 gcagttacta tacctttttc aggaagaaga acatgctcta ttcccatatc tcctacatca
     3541 aaaaaattta caactccttt tgattttgcg aaacttcttg taaatttaca ttgttctgca
     3601 ctctttatat ctttattagg tgtaaagtgg tctaaaacca tcactacttt agtcttatca
     3661 taaacatctt caattcctaa tttttcaaat tctctaatgg ctactggtga tgttatatca
     3721 ttacctaaaa ctacatctaa atctgcttcg attaattgcc ctttcttaac ttcatttaat
     3781 ttagcatgtt tggctaatat tttctgcgtc atagtcatcc ccatttttta tttcctcctc
     3841 aatataactt ttatttattg cattcataag tgcattaata gctgctgtat ttatgttttc
     3901 cgatatactt acaccaaaat agacttcatt attgtgctct attcctacat aagctacccc
     3961 tcttgaatgt gacccttcct ctaatgcatg ttcccagtaa tatctaaatt tataatcttt
     4021 catgccacat tgctttagtg cattattaaa tgaatctaca ggtccatttc ctataccaac
     4081 aatcctttgt tcatttccca tataacttat tcttgcagtc atctcaatca tgttagtatc
     4141 attagaatca tcattttcat agtttaattc atccattgat tttattttat acttcttaac
     4201 tttataaggg ctctcaactt caatatattc tttcttaaac aaattaaata ttgcttcact
     4261 actaagttct tccccaattc tatcagattc cattttgact acatttccaa aatcagaatg
     4321 catattctta ggtatcataa atccataatc tgtttccatt atataaacag ctcctccttt
     4381 tccagattgg ctatttatcc ttataatttc tttgtattct cttccaatat catgagggtc
     4441 tattggtaaa tatggaactt cccagtaatc attatctctg tttttcattg ctatcatgcc
     4501 ttttctaata gcatcttgat gtgaacctga aaaagcacaa tgtacaagat tacctgcata
     4561 tggatgtcta tcatgtacca taagttttgt acagtcttca tatataccta ttatcttatc
     4621 tatattgcta aaatctagct ctgggtctat tccttgtgta taaagattaa gtcccacatt
     4681 tactatatcc atattcccag ttctttcacc atttccaaat agtgttcctt caagtctatc
     4741 ggcaccagcc aataatccaa gttcacttgc agccgtacaa gttcctctat cattgtgagt
     4801 atgcaaactt agtataatag aatccctaca acttatattt ttacaaaacc attctatttg
     4861 gtctgcatat acgtttggtg ttgccatttc aactgttgat ggaagattta ttattacttt
     4921 tttttgagga gttggtttcc aaacatctat cactgcctca catatttcaa gtgcataatc
     4981 catctctgtt cctgtaaaac tctctggtga atattcaaaa gtaaattctg tttctggata
     5041 tttttttact tcttcattaa ataattttgc tccttcaact gctatatcta ttatttcttg
     5101 tttactcata ttaaaaacca catctctttg aagaacagat gtagagttat ataaatgtat
     5161 aattgctttt ttacatcccc ttattgattc aaatgttttt tctataagat gagccctaga
     5221 ttgtgtaagt acttgtatag ttacatcatc tggaatcata ttctcatcta ttaattttct
     5281 taaaaatgta tactctgtat ttgatgctga tggaaatcct acctctattt ctttaaatcc
     5341 tgtatcaata agcattttga acattctgac tttttcattt acactcatag gtgttggcag
     5401 tgactgattt ccgtctctta aatcgacact acaccaaatt ggagccttaa atatttcatt
     5461 atctggccat ttacgattta ctatttgcat tttatcatat tttttatact ttccacactt
     5521 catgttattt cccccttttt ctgttttttg tattcagtat acctcatatc gacgcaatcc
     5581 tgcacaattc ataaggataa atgtcaattt tatcattaga ataaaaaaaa cctcatctct
     5641 aataaaatta gagacgaggt tttgctcgcg gtaccactct atttagcttt ctaaaaagct
     5701 cccttagtaa tagccaatac aataattata atgactatat ttcctataac gtggaattac
     5761 tccgattatt ctaagattta aatcttagaa aacagctcct agacaagttc agaactatca
     5821 actactaaat cacaccatcc tttagctctc tgaaagtttc attgttctta ctacttctat
     5881 tcatcacttt tttaatcatt taaattttct aaatattttg atttaatagt tattatatac
     5941 acattaaaat gtattgtcaa cacaaaaaat aattatctca attttttatt tttgataagc
     6001 aattctataa aacatgctaa ctattgaaaa cagtatgata ttatgcctta aactttttca
     6061 tcttttcatc tatgatattc aataattttt tttcatcttc cgaactcaat gcccttaatc
     6121 taattttata attagattcg tcagtgtata tatttaatat attttttact acttctattt
     6181 tttctattat cttataatta aacttttgac tttgtttaga ttttatactg aatatacatt
     6241 gattatttat taatattgaa tgattatcga gagtaatata tacttttccc tcatatttat
     6301 ttgaaaaatc acgaccttgt ttaaatagaa aaactgctgt tattatacat aaaatatata
     6361 atattgtcgt tgaatatata aaaattgtag ctaaaattat aagtgctaaa accatatata
     6421 tagtcattcc ttttttaaaa taaccattgt cataataatt catatagata aacttatttt
     6481 tactcaaatt ttttcactcc caagattcta aaaatttata tcaaaaaatt ctataatttc
     6541 atcttcatga taatttatga ctaattcatc tggaaaatct actgcttcta aaactttttc
     6601 tgcattttca aattctccta tagaataaca tatatgagag tcagtaccaa gaattactct
     6661 tgcaccatag gttttacaca atgtcaacat atgacttaca ttttcccaag tacccgttct
     6721 atgagagttt gaacttaatg atgaattatt tatttctaaa aggatatttt tatctttagc
     6781 tttttttact ataggttcat aatctaaagg atacctactg tcatctggat gtccaattat
     6841 ttttacctta ggtttatcca taacttttaa aatagcattt gtattttctt cttttgtacc
     6901 agaagctata caaggtctat gcaaacttgc gattatataa tccaaatgtt gcaacatatc
     6961 ttcttgaaca tctaaattac cattataatc cattatattt ccttctattc ccctaagaat
     7021 ctttacgcct tgcacttcac gtggaagcaa atgcaaatta taaaaataga atggatgtgg
     7081 tcctcctggc atattaggtc catggtctga tattcctaag tattttatat tcttcttact
     7141 cgcctcttcg acattttcct tgaaagtact atgtgcatgt ccacttatta gagtgtgaca
     7201 atgtacatcc ataatagact ttttcattaa atttcctcct aatattttac ataaattcgt
     7261 gaaaatagct aaagggctat ttcaaaacta aagctgtcat aatagacagt gtaacgtttt
     7321 aaaacagccc cattttcaat tattttacac ttctaaatct ttaaatttat ctttaaataa
     7381 ttctccaata cttcctaaag attcctctac ttctaggtat tctgttatat cctcttctgg
     7441 ctctctagtt gcttctttta ttgaaaccaa cattctttta gtctttggtt taaaatcaag
     7501 aatcttaact ttaacctcat ctccaatatt aacaacatta gtaactttag ccactctagt
     7561 atcactcaat tcagatattg gtaaatacgc atctacacct tctttaattt gaacaaaagc
     7621 ccctttttct attattctaa gaactttagc attgacaaca tcatcaattt gtacttcttt
     7681 tgctattaaa tcccaagggt cattatttat gtcttttaat gccaaggcaa tttttttagt
     7741 ctctttattt acatccaaca cataaacttc tacttcttgt ccctctgaaa caacatcttc
     7801 aacactttca actcttgtcc aagctaaatt atttatatgt gctaatcctt caatcccacc
     7861 aatatccaca aatgcaccat aaggcattat ctttgtcacc ttaccatctc ttttttgtcc
     7921 aacttcaaga gaattaaata agtcttcttt agctgctttg atacgagcct tttcttcttc
     7981 tctttcttgc ttaattcttg ctctttcagc ttctttttct gccttaattt gagctcttct
     8041 ttcttctctc tctttattta tacgctcttg taatacatct ctatgagatg ctacaagtct
     8101 attttttcta acatccaatt cttttatata aacttctaag ttaagaccaa caaatttaga
     8161 tgtatctgta ataaattttg tatcaagttg agaaattggt ataaaaaatg tatatgtatt
     8221 gtaattagca aatacacctt tatctatatt cttttcaaca tttacagtta ttattctatg
     8281 ttcatcataa gccttttgta actcggcaaa atcatttctt ttgtcaagtt gtaatttaga
     8341 taaagttatt gtaccatctt tttgagatac ttttgttatt acagcagtta tttcatcacc
     8401 tatgtggtat atatcttcta tatattgatt tttttctatg ttcaattcac ttataggtat
     8461 tattccatca aacccatagt ctaatcctaa ttgtacttca tcatttctca ctgcagttat
     8521 ttttccagtt gtcaattctc caactttcac tttgctgaat acttgttctt gctggtcaag
     8581 taattcttgc attgttaaat cattttccat tataaacatc ctttcctctt attgattatc
     8641 atatctgtaa atattatacc attaatattg caaatactta catttttctt actataattt
     8701 ttaaaataaa ttcaacttca tatatttata cattatagaa aatatcttat taaattaaaa
     8761 tacaaattct aatttttatc taataaaata ttttcataaa aaatttatat tgtatatctt
     8821 attcttttat tgctttaggt tttgatagaa aacatttata aaatataaag aaagaaattg
     8881 ctgttatagt agcagctgtt atatctgcaa ctggctctgc taaaattact gcaaaaagtt
     8941 tttcattaaa gaatgttgga agtataaata ttaaaggtat taaaagtaca atctttctaa
     9001 gtagagctaa aaccaaagat attgttgctt ttccaagtgc taaaaatgtc tgttgacaag
     9061 ctatttgaat cccaaacata aaagcaccag caaaatatat ttttatactc caactagtca
     9121 tactaagtaa ctgcggattc ttattaaata tactaacaaa aaatgcagga aatatcatta
     9181 ataaaagcca taaaatagta gaatatgtaa aacatgacaa caaacacaac ttaaatgtct
     9241 tttttactct atcaagttga cctgaaccat aattataact tattattggt tgtgctcctt
     9301 gtgtaacccc catattagga agcataagaa tttgcattat actgctcatt atagccattg
     9361 aacctactgc taaatctcct ccatacattt gtaatttact atttaaggct ataagtacta
     9421 aactttctgt agattgcatt ataaatggag agattcccaa accaagcact ggtaagatga
     9481 tacttgcttt tggtatcata tacttctttt ttattttaag tatacttttc tttccaaaga
     9541 gaaacataag tacccaaata gcagaaacgc cttgtgcaat tatagtagct aatgcagctc
     9601 cttttacacc catattaaag ccaaatataa aaatcgggtc aagtattatg tttattaaag
     9661 cacctatagc aactgtcatc attccagttg tagcaaaccc ttgggtattt ataaaagtat
     9721 tcatacccat tgaaatctga acaaacactg tacctattaa ataaatattt aaatagtcca
     9781 ttgaatatcc aattgtagat tcacttgctc caaacatcca aagtaaaggc tcttttccaa
     9841 tcttaaaacc tatagtcaaa agtattgcta aaatcaccag tacagaaaaa ctgttactca
     9901 ttattttctc tgcctcatca ttgttttgct cacccatttt tatagcagct aatggacctc
     9961 ctcccatacc gattaaataa ctacatgcag ttattataat tattattgga aatgccactc
    10021 caacaccagc catagcaact tctccatttt ccattctacc aataaaaatc ctatcgacta
    10081 tgttgtataa aacatttaca atttgtgcga taatagcagg tgtagcaagt ttaaataata
    10141 atttacccac actttcacta cctaagttag tgtttgaatt ttccatttta aaacctcctc
    10201 aatccaataa ttaaaatgta tcactaaaat tttattctat ataaaaattt cattttatta
    10261 gcagacaaat ttagagtact ttccctacaa gtaatactat actatatttc ttttgccata
    10321 gtaaacattt tagaactaac tgaagttaaa tactttatct cattttttat ttattattaa
    10381 aaatttttca catatactca taaaaaaact atccaagtat attacttaga tagttttata
    10441 ttatatgtaa agaaagagct gaaactataa cccctgataa caaattgcca agaaatactc
    10501 ccataaaagc atcttttatt ctcattttta atatggaagc tatagcagat gcagtccatg
    10561 ttcctgtagt tggcagtggt atacctacaa atagtattat accaattatc gaaacacttt
    10621 ttaatttctt cattcttgag tttatttttc tatcaattac atcagcaatc cctttaaata
    10681 gtttcttccc tcttaaaaat tgtaatacat gtctgaatgt caatatcaag ggaatcgata
    10741 ccaatgtaga acctattaca ctaaatacat aaacccatat aggatttaag cccattgcaa
    10801 tacctatagg aatggctccc ctcaattctg ttacaggaac catagataaa attaatatgt
    10861 gtaaatatcc caaactattc cctcctattc taagtgacat taagttatga atttatttgc
    10921 tctataacct caccatcctt tttactaact aaaaatgcat ttttagtcaa tgaaagcatt
    10981 ggtaaatcac tcttagagtc tgaatatgca tatgaatttt cataatcaat ctctatccca
    11041 agtttaccta atacagcctt tattcttttt actttttcaa ttcccttaca gttttctcca
    11101 atgaattgat ttttatatct tgaattttca taaaaaaact ccgtgcctat aacctcgtct
    11161 gcaagaccat aatacttaaa atatttcata tatgcatatg gagatgcagt tatcataatt
    11221 ataacattat cttcttcttt atttttgtaa ataacctttt tcatagattc gttaattttt
    11281 ttcattatgc aatcatcaaa aaactttttt aaatcttctt cactaaaatc tactattgga
    11341 taaaagattg cctcttttgc cttcttcaag ggtatcattc taattaaata cataaataga
    11401 ataaaaataa tgtatggcaa ctttataata gttttaaagg ttttattttt taaagagtaa
    11461 ataaaaaaat ctatcatgct atcagtattt ataacagtat aatctacatc aagtaataat
    11521 acactttttt tcataagtat ttccccatcc tatcactaaa aatatcacta aaaaatcaat
    11581 attattaaac atgtaattat ccataagatt acgtttattt ttaaagcatt atcttttagg
    11641 acaatatcag taggattatt ttcatttgta gtgttaatta tataattata tctaagtaca
    11701 ccataaacta caaatattgt tgtaaatatc atatgtggct tttctggatt acttgtagaa
    11761 tacaatgcat aacatacaat tgtagaactt aatataacta tcatcatttg atttagattt
    11821 tctatgtcat aatcttccaa tatttttcta tgttcaactg catcatctct tagagtttct
    11881 atttcttttt tacgttttcc aagagctaag tacagagata agaaaaatgt acataaaatt
    11941 atccaatttg ataaactaac acttatggct acacatcctg cataaaccct aagtataaaa
    12001 ccaagagata ttgaaaacac atctaatagt attatattct ttagtttaag agaatataat
    12061 atattgttta tcaaatagag actgagaatt atagaaagat taaaactaac aactgttgat
    12121 aaacagactg aaattaaagc taatactaca aatagtatat tagcactttt tttgcttatt
    12181 cttccacttg ccactggtct attacatttt ttaggatgtt ttttatcttt atccatgtct
    12241 atagcatcat tcagtgcata tactgatgat gacattagac aaaaacacac aaacgcaata
    12301 aacgtattta aaaataaatt tatatttagt atgttgtttg aaaaaattat agctgaaaat
    12361 acaaagaaat tctttatata ttgctttatt ctcattaact ttatataatc tgaaatttta
    12421 gtaagaagcc ttatacttgt attggtctgt ttcataaact tactaccctt tcaatattat
    12481 tttttaaaca ggatatgatt ttatccctat gtttaaaatt tctataaatc cattgacatt
    12541 actgattact atagtaacca ataacagcga tagaaatata ttatacatat tcttttcatt
    12601 ttttctaagc gctttcgtaa agtaagccaa taaaattata actgcaaaac taaaatttat
    12661 agccataata cttgaattga ctagattata tcctactata ccatgtaaag ttagattgaa
    12721 tataattatt cccatacata gcttaggaac tcttttttct gaattttcaa taactgataa
    12781 aacacaaaaa cataaagcta ataatgtaag aattactggt attgtagcaa cttctccatt
    12841 ttgcaaaaat aacccttttt taatacttgc tccaggaaaa taaaaaaccg aatacaataa
    12901 tctctctata atcattgcaa tcttttccaa aattggttct ccacttataa atttcgtatc
    12961 atactgtatt acatttccaa ggttcataaa actctcataa gacttcgttg aaactacaca
    13021 aatatatgcc attaggataa atgtaattaa atgttttaac atttttccta tttttaattt
    13081 aaactcaaat atcatattaa aaaaatacaa atatatatta ctaatagtta ttccaaatag
    13141 aggaatagct gctaattcta ccaaataaga attttttcct ttcatcttat ttgcaataac
    13201 tatgaaaaat attaatgaaa attggctata tataaatctc tctacattta aagtcataaa
    13261 taactgtgga aaagaaaata tcattatcat agtaagtaaa attaaagtta atctctgcat
    13321 ttttatcttt ttaatatgat taaagactaa agttattgac atagcactag ttattatttg
    13381 tagacaaatt agtccaaacc cataggcact attaaaatct gttgtcccag gatttgctat
    13441 tgaagtacaa aataggtata ttggatatgc aaaaattgat ataattgctg aaaacaatat
    13501 gtgcttacta ttgtcttgac ttatagcaaa tacatttaaa ttgaataaaa ctcctgtatc
    13561 tgtatctaac aatacatcat aagtattgtt taaatcataa aatatagtag tcttagaaaa
    13621 aaatatctta gttattatta agtaagttat tacaactaat ataaacaaaa acatctcgtt
    13681 tttatatttt aatattttac tcatcaatat atcaccatcc attcattata taggatttgc
    13741 tgacacctac aatttattcc ttatatttaa tagccatctt cataatgttc ttacttgttt
    13801 tattgtaatt gaataactct ttatttacaa ccacaatatt tactttattg atgttataat
    13861 cagtcaagta ttgtttatat aacatagatt agtgttgtat aaaatgagaa tttgtaagca
    13921 atattaatgt aaaatatttg aaaaacttta tataaaaata tacaatgtta cttatggaat
    13981 taaactataa caaattaaag cataatttaa ggagacaaaa ttataatctg tctccttaaa
    14041 tattaaaact atattttaaa acattactaa atactataca aatttcaaat atagtataaa
    14101 attaattaga ctttaacact attagctcca tcttcttccc attttttaat ttcttttaat
    14161 ctatctatta taggtaaatg ctgagtacat tcaacttcac attttccaca agatatacat
    14221 tctttagctt ttgccttact attcattgtg taattccaat gtcctaagcc ataaactaac
    14281 tttgtcattt cttcatcact ctttttaaac atctgctttt cattataaaa aagcatatag
    14341 gctggggtat taataccttt tggacatact ttacaataac cacaacctgt acatatttcg
    14401 ttcatattct tatttaatct agtctcaata tcatgtatat cctcatctga ataaattcta
    14461 ttttcgtctg caattttaca tgcatcatct atatcttgtt ttttattaaa ccctatcaaa
    14521 gatatactta tttgtgaaat tcctatgttg aatcttaaag ctgattctat agtactttcg
    14581 ccatcttttg atagaaaaga aagttcttta ttatactttg gaatagttcc accacttaat
    14641 ggattcattg ccacaacacc atatccatta tcaacagcat atttggcacc ttttagccta
    14701 tatggaaagt ttaatatatt tattcccata gttacacctt caaacttatt ttcacttaga
    14761 atatctataa cctcatctcc tggttgatga gatgaaaata ctatatggtc tatcaatcct
    14821 tcttctttac atttcaataa tccttcatat tgacctccag gtctcattgc tagttcgtaa
    14881 tgttccatct ttctaatatt ccaaacatga taaaaattta ttttagatac gcctaatcgt
    14941 tctattgatt tttttacagc ctctatagct ttttctgatg tatcacatgc ttttggcttt
    15001 tctttagttg atacataaaa atcggtctta ccttccttta tcatttgtct aaaggctagt
    15061 ccaaatatat cttcacttct gtcatcacaa taccctggtg ctgtatcaaa gtaattaata
    15121 cctttttcat acgcatattt gactaaatca gcattttctt gattactttt ttctaaatca
    15181 aaccttaatc ctccatagcc aactactgaa accattttcc ctgtctttcc atattcaacg
    15241 tatctcattg taaattcctc cttagatata ttaagactta atttctttat agaaaatatt
    15301 ataccataaa taatttttat aaattattta tggtataata ttttttttat aaattatatt
    15361 tttttataac ttgtatttta taactaagtt aaaaactata aaaaggttca atatggacta
    15421 ttacttgagc attttcatta atttcttctt gtatttgttt ctcaatttta tgtgttaaat
    15481 catgagattg ctctacgctt ataaatgggt ctaccattac atgcatgtca atataaatag
    15541 aacttttgct acctctactt ctgatattgt gaacatccct tacctcatta aattcaaaca
    15601 caatttcttt tatataatcc tcatctacag ccactctatc gaccaaaatt ccaatagatg
    15661 gcctaaatat tccataagcc gaataaatta tgaatgcaga aataataata ggaactatag
    15721 attctattat tactggaaat cctaacttaa caccaactaa agtaaccaat acacctagag
    15781 acacaaatat atcacttctt gtatgcaatg aatccgaaat caaaacataa ctatttagtt
    15841 tagtcccaat tctatattca tacatgcata caaaaatatt tataaaaagt gtaataatta
    15901 aagcaattaa actttctata gttatagcag gtacaactgg attagctatt cttaacactg
    15961 cactaagaat tatcttaatt gctataacaa acaacatacc acttataaat aaactggtta
    16021 taatttcaaa ctttttatgt ccataaggat gatttttatc ttttggttta gatgcaaaga
    16081 aaatacctat aagccccact atattagatg ctccatctga caaagaatga aatccgtctg
    16141 ctgtcatact atagcttttt atttgattac caataatgat ttttaataat gctactgcaa
    16201 aattagcaaa taaaattatc cacaatactt gcttcacttt cttatagtta tccataacaa
    16261 attccccctc ccttcgattc aataaagaaa gctatctatc aatatcaatc aaccagacaa
    16321 taaaatcgta tataagcaca tttactatat ttatattcaa aattggttgt acttgttcat
    16381 tctatttgaa acttaattat aaataaaaat cgtaggtatg gttttggtat acataaaaat
    16441 aagagactgt ctcaaaataa agataatctt cttttttatt gttgaaatga taaaatatat
    16501 ttgatttaat ataaaaaaga gtgcctcatg aactaaaaag ttcattttga gacactccct
    16561 taaatttttg atataaacta ttaatttttt atactaagcc ttctttaact aagaatgaat
    16621 gagcaacttc ttctggtgat ttaccaagtt catccacttg atagttaagt tctctcatag
    16681 tttcttcatt tatttttcct gaaagcatat tcataacttt ttctaactca ggatatttct
    16741 tcaaagtatc ttctcttact aatggtgctg cataatatgg tacaaagaaa tttttatcgt
    16801 cctctaatat cttaagatta aactttttaa taagaccatc agttaaaaat gcatctataa
    16861 cctgagattc attattatct aaagctgtat atcttaaact tccattcatt gcttttacat
    16921 ctttgaattt taaaccataa tctctagaaa gccctacaag accatcttct ctattttcaa
    16981 actccaaagt tggtgagaat gtaaattctt taccatattt agtcaaatca gaaatagtat
    17041 ttattccata cttttcagca gtttcaggca tcatagctaa tgtgtaagta ttattaaatc
    17101 caagagggtc aagtaaagtt aactgatttt ctttttccat agtatctttt acaacattat
    17161 atgcttcatc agcatcttta atcggagcat gtttcattac atttaccaaa agtgtacctg
    17221 tatagtcaac atacatgtct aactcaccag atttaattgc attaaacgca acagatgaac
    17281 cacctagatt taaattcttc ttaactttaa gattcgtatt tttttctact aattcagcat
    17341 aaacattacc aagtataagt tgttctgtat aatctttaga accaatagtt attgtatctt
    17401 ttttacttga aaaactagaa ctaaaaacaa cgaacaacat tgaaacaaca accactacag
    17461 atattacttt aagtgctata taattcttct taggtgcttt tggatttaat ccttttggag
    17521 taactgcaac ttcaatttta ctaaataaat aatcaactaa cagtgcaatt atacatgatg
    17581 ggattgcccc tgctaaaatc atattattat ttacagtttg aacccctgaa aatactaaat
    17641 atcccaaacc accagcacct ataaatgctg caagagtcat caaaccaaca gctgtaactg
    17701 cagatattct aactccaccc attattatag gaagtgctaa agggaattgt attttaaata
    17761 atgtctgatt tcttgtaaga ccaatacctt tagctgattc taatactact gggtcaatac
    17821 ttgttatacc tatatacgta ttttttacaa ttggtagtaa tgaataaacc actaccataa
    17881 atatggctgg tttacttcct ataccaagta taggtacaag aagacccaaa agtgccatag
    17941 acggaactgc ttggactaag tttacaaatc caagtacaaa ctttctaaga gatgagattc
    18001 ttgaaataat tattccaaga ggaacaccaa ctattatagc tattaaaata gatgtaacag
    18061 ttagactcat atgttgtatt aaaagctcta taatcttatc tttttgtaat agtataaagt
    18121 taaaaaaatt agccaagaac gctcacctcc atttctaaga attgttcact taaaacagaa
    18181 agtaaactac ttctagtaat aagccctacc agtttatttt catcagaaat aaccggaata
    18241 tatccaaccg aattacgatt cattacattt agtatttcta ctaaattatc accttcattt
    18301 acatgcaaag gctcacttga cataatatca gcaagtaata ttgacttatc atcaatatct
    18361 ttcatatctt ttacagtaac aatacctttt aatgtttttg ctctatctat aattagtaag
    18421 ctatcaacct tactcgttct cataatttct attccttgag ttacagttct agtagaatta
    18481 acagcaatag gattttttat cataatatct cttgctttta tatattctgg attatcccaa
    18541 actctatctt ctccgataaa atcttttaca aagtcatttg caggctttct aagtatattt
    18601 tcgggagtat catattgtgc tattcttcca tccttcataa tacaaatttt atcagctatc
    18661 tttaaagcct catccatatc atgcgttaca aatattatag tttttttcaa ttcatcttga
    18721 agagaaaata attgttcttg taaagatgtt ctcgttattg ggtctaaagc actaaaaggc
    18781 tcatccatca atattatttc agcatcagta gcaatggctc ttgcaacacc gattctttgt
    18841 tgctgtccac cactaagttc tgaaggatac ttattcaaaa attcatcact atcaagtcct
    18901 accatctcaa gtagttgcaa cgttcttttt tcaatttctt caacggattt ttcctttttt
    18961 aggcgtggaa ttagctctat attttctttt attgtaagat gagggaatag gcctgtgttc
    19021 tgtataacat atcctatttt tcttctaagc tctatttcat tttcctgaga aattggtttg
    19081 ccattaatat atatctcacc agatgtaggt tttattaatt tgtttataag cttcaaagta
    19141 gtagtctttc cacaaccact tgaaccaatc aaaactacca atgtacctgt ttctacagct
    19201 agagaaatat catctaatat aacattattt cctatttttt ttgttacatt tcttatctct
    19261 atcataattt atcatcccct ttttcgaaca agcaaccttc tccaatatta taagttgttt
    19321 ttataattat atcatactat tttatttatg taaacaaagt acgattttta ggtcactatt
    19381 tgtctgaata ttgctacaaa tataaagtat ttatatatag tatataatat ataatgtcaa
    19441 aaaacaaaaa atataaaaat attcataaaa taacactagc ctcaattata tagtattaaa
    19501 gctagtgtta tttcatttaa acaaaactca catttggata ctatccatgt attcaaataa
    19561 tgtaatatct ttataagttt cttttttatc acttaagttt gatattgtaa ctcccaatag
    19621 cctaatttgt tttccattaa cctcaacatt tctcaacaag ttatctacac cacttcttat
    19681 atcattatat tcgtcaatat agtgttctaa actaaggctt ctagttatct ttgtaaagtc
    19741 ctcatattta atttttaatg ttaatgtttt tccaaacttc tcagagtttt ttaatctatg
    19801 acatacttct tcacaaagtt catcaagaat gttgcgtgtt tcttcttcat caatatccaa
    19861 attatgactt aatgtagtct cagccccaac agattttcta accctatttg gttccactgg
    19921 tctatcatct attcctctag caaatttata taattcataa cctctttttt tgaatatatt
    19981 ttcaagttca aataaattta aacaccttaa atcatatcca gtttttatac ctaaattttt
    20041 aagagtattt gaagtaactt ttccaacacc aaaaaattta ttcacaggta atttatctaa
    20101 aaagtcctgg gcattttctt cggttattac agttaaccca tttggctttc ttaagtctga
    20161 tgcaatctta gcaagaaact tattgtatga cacaccagct gaagaagtaa gaccaacttc
    20221 tctaaatata tcttttttta tttgctttgc tatctcaatt gatgaatcaa tatttttttt
    20281 attttttgtt acatctaagt aagcttcatc taaagataat ggttcaacta aatccgtgta
    20341 tctataaaat atatctctta tttgctctga cacactctta taaacatcaa atcgaggtct
    20401 tacaaaaact gcatatggac acctattgta agctacagct gatggcatag ctgaatggat
    20461 accaaatttt ctagcttcat aagaacatgt tgcaaccaca cctcggcttt gtggatttcc
    20521 accgacaata acaggtcttc cttttaattt tttattatct ctttgttcta tagatgcata
    20581 aaaagcgtcc atatctatat gaattatttt tctataatgt ttcattatta tcacctttta
    20641 aagtataaat agattaattt tatttatatt actttttaat tataccaaac ttatgtttct
    20701 ttttggtatt ttttcattat tttctttata tattcatatt ttccataaat aaaaccatct
    20761 ataatccatt aacttcaata taatttataa aaaatcctta aaaacacttg caaaaactat
    20821 ataaaagctt tacaataggt attccaagga actaaattta aaattcctta tggataacag
    20881 tatatatatt taatttatgg gatgttttaa aaacaaaaga ctgtcttata caagacagcc
    20941 tactgatttt attataattg taatggactg ctcaaactat tactttaaaa cagcccatat
    21001 ttttttatat aattttaact atagtaaaga ttttgtgaag gatattctgg gtcacaagtt
    21061 acatctatac caagctttct aaatgtttgt tcatcatctc tatttaatat agtagtagaa
    21121 tgagcttgac acccttttaa taatgctaac ttttccatag caaattgtgc agttggatta
    21181 gttacagcac aaatactaag tgcagttaac acctcttggc aactaagtga aacatttcta
    21241 ctagctaaag tctttgtttt taagtttatg ataggttcta atattacagg tgatattaag
    21301 tgcatatcat cagatatatt ggctaaatgt ttaatggcat ttaatactac tgctgcagtt
    21361 ccattcatta aatcagaacc cttaccagtt aatattgtac catcttctaa ttctaatgca
    21421 actacaggac aagtatcatt cttgtcggca ctttctttca atttattact gtagtttcta
    21481 gcaggtaata caacatttct atcttctggc tttaagttaa gctcttccat aatcattttc
    21541 attctatcat aagcaccttt atcaacttgt ccctttttat actcacaggc agttttaaag
    21601 tatcttctta ttatttcttc tatagaagct tttcttatta cttcatcatc tattattcca
    21661 aagccaactc tattaacacc catatcagtt ggagattgga aaattgattc ttttccagtt
    21721 atcttttcta ttattttttt aagcactgga aataattcca aatctctatt gtagtttact
    21781 gacatttcac catacgtttc aaggtggaat gaatctatca tattcacatc ttttaaatca
    21841 actgtagctg cttcataagc tatattcaaa ggatgtttta caggtacatt ccaaactggg
    21901 aatgtctcaa acttagaata tccaactaca ttacctcttt tattttcatg atacaactga
    21961 cttagacaag taccaagttt tccactatta ggtcctggtg ctgtgactac tactattggc
    22021 tttgtagttt ctatatattc atttgctcca tatccctcat cactaactat agtctcaaca
    22081 tctgacggat atccctttgt tggataatgc ttataaactt taattcctct acgttctaat
    22141 ttatttataa atacagttgt agcaggttgt ccttcaaatc tagtaattac tacactattt
    22201 acatctagtt cataacctct taaatcatct attaatctta aaacttccat atcataagtg
    22261 ataccaaagt ctcctcttat tttgtttctt tctatatctc ctgcatagac acaaattaca
    22321 acttcaactt tttctttcat atgttgtaat acttttatct ttgcattttc atcaaatcct
    22381 ggaagtactc tttttgcatg aaggtctccc atcaattttc ctccaaactc taaataaagt
    22441 ttgtcaaaat tatttactct ttctaagata tatttagact gctcttctaa atattttttg
    22501 tggtcaaatc ctactttcat cttaacacct cactaaatta aatttcttgt tgataacagt
    22561 atatttatat atattttttt agtaaaacat cttataaaaa aatgttaata ctttttcact
    22621 caaagtaata ttatacaatt aagattaatt tttttcaaga tagttttatg gtaaataaga
    22681 tatacctata taactaataa aataagaata ttatattttt atatataagt ataatattct
    22741 caccttagca ttaatttatt tcaatatttt catatatctt ttattctaaa ttcaatactt
    22801 ttctaatatc ttctatacct tgataaactt cttgtttaga aaaattcata gcttctaatt
    22861 cttcatcagt cttttccata agcatagtat aaaattctat tgctatatac tgcatatttt
    22921 cactatttac actcttagct ttatcaaata aaatttcttc tgcttcgttt acatttccct
    22981 gaaaaactaa tctttttaaa gttataagta taacttcttc ttctgtatta tacactaaat
    23041 ctttttcttc atattcactg tatttttttc ccaataaaag tcttgcaacc ataagtttta
    23101 tctcattgaa aatcttatcc actatagcca tttttacatc tcctataaat aaattttatt
    23161 ttctttttaa ttatatcaga ctttatcgta aaaattatta tatgtaaatg aaataattca
    23221 aaaataaatt ttaacaataa aaaaaagaag gtagcggggg atttccgact accttcaaac
    23281 actagattgt gattggtttg gtattttatt tatacccacc ataagcttta ttaaatcatc
    23341 taaattgatt tttttagcat ccacatcctc catcaaaaac gtcaccacat tcacaaagta
    23401 ttaataataa tattaagaaa ggtatccatg cacataagtc catttcagcc caacaatctt
    23461 ggaatgctaa gaataagaag aataatatta ttatccacca agcacatcca ccaaatccgc
    23521 cttcaccaaa aaatctatcc aacataatat gttacctcct agtcattttg tatgtggagt
    23581 ttcagctcct aaaatatact atgtttaagg ggtaatattt gctaatgatt tttttaaatt
    23641 tttttagata tttttaaaaa aattattgat tcacactcaa tgtcttacca tcactattga
    23701 taactacctc tccattagaa gtcaaaaatg tttttatatt caatctttcc aatattttta
    23761 aaacaccttc ctctggttct tttttctctg aacatgtaat aacagcatat tggggtgaaa
    23821 tagactctaa aaatgtttca gttaatttgt catatcttcc atgatgaggc attttaacaa
    23881 aatcatattt taaagtattt ccatttataa actctgacaa tctttcttcc tctgcatctc
    23941 ctgcaaataa aaacttatgt gctccatagc ttatattagt gattattgaa taatcatttg
    24001 aactctcgta cttgcttttt gaagccggat gtatgtttat ttctgcacta ttgattacaa
    24061 tattcatatt atcttttagt agcactggtt ctatatcagc ttttttaagt gagtcaatat
    24121 attcatcata ttgcttacta tctttcttat aatttgcttg tataatattc tttactttaa
    24181 tactagataa cacactatct actccaccta tatggtcctt atctaaatga gttaaaatca
    24241 aatagtcaag tgtatttatt cctttttctt ttaacctatc cactatttgt tttccatttt
    24301 tatcttctcc cgtatcaatc attatgactt tgttacctat ctcaaccaat atgcaatcag
    24361 actttccagt gcttagtata gtagtcttaa atgcagtatt ttttgtgcta ctctttgtgc
    24421 tcctctggat accattttgc ctcacactat ttttgtcact ttttaaataa gattcacttg
    24481 ttgattttat cttactatta gtagttatat ttgttacaag caataatatt actattatag
    24541 ataatgtagt aactaaaaac aggatatctt ttaatactat tttcctcatc caaaagctcc
    24601 tataaatttt atttattaca tatttatagt atagcaacct taactctgta aaatacacat
    24661 ataaaaaggg caaattttag gcatatttgt ggcataataa aaaaatgact gtaccaaaac
    24721 aattatcttt ctaaatttac atcttcaaat tctttaatct tatcattaga taaaacactc
    24781 tttttagtag attgtccatt ttttctatca aaagtatttt tagcttttac acctgataaa
    24841 aacttacctg ctccattaat acaaccttct tcacacatca ttccttctat aaaattacct
    24901 tctaatcttc ccaatttagc cattgtcatt gtctttttaa tttgtcttgg accagatact
    24961 tttataggtt caaaatcaaa actaagcccc ttttcagcaa tatagttctg tactgatttg
    25021 gcaagtccac cagatgctcc aaatcccctt ccaaaaatcg aaccatcatt tatatcttca
    25081 tttgaacatt ttgataaatc tatattaaat gcttcaaata atgccattag ttcttcaaaa
    25141 gtaagtacat aatctactga atcttttaaa cttttctctg ttgcctcact ctttttagct
    25201 gtacatggcc ctataaatac aactttagca tcagaatcta ttttttttac taatcttcct
    25261 gttgctacca taggagacac tgtagatgat attctatctt tttcatctgg gaacatcttc
    25321 tctatatact taaaaaatcc cggacaacat gaatttgtca tgtaattatc tcctgatttt
    25381 attctttcaa taagttcatt gctttcatga actgtaactg catctgctcc acaagaagct
    25441 tctatcatat ctacaaatcc cagtgatttt atagcatttt ttaactgacc atatgtaata
    25501 ttactatcta tttgacctgt tatagctgga gctactattg catacatatt ttctttcttt
    25561 gcaagttttt ttgcaacagg tgctatcaaa ctcttatcag atattgctcc aaaaggacat
    25621 gctgacatac atgctccaca atttatacaa ttatcttcat gtatcattgc tttcatagtg
    25681 tttctattaa aatccaaagc tcctgttgga caaacgcttt tacaaggtct tacaatttct
    25741 gatatagcat catattgaca tgaacttttg cacattccac aagccttaca taaatcatga
    25801 tttatatatg ctctcccatt tatataagaa attgccccaa atttacatgc ttccttacat
    25861 ctatgagcca aacaccctct acaaagctct gtaactgtaa attcatttat tggacatcta
    25921 tcacatgctg cttcaactat atatataatt tgctcatctg tgtccaaact aactgaatct
    25981 ggatttatat ctccatattt actatttgga gttaaactta atgcaagttg cgccctttca
    26041 agaactactt ctctctcttt ataaacacaa catctatatc tcgccttttc tcctttaatt
    26101 atttcatatg gaattttttc tatattttct tttgttaaat tttcttcaat agatagtctt
    26161 gctactgctg ttaaaacttc atgttttaac ctttttagtt gcgtttcaaa ttcaaacata
    26221 agtaatcctc cctataaatc acaccttttt gctatatttc tactattatg tatattgtat
    26281 tttttattta tttctataaa ttattataac ataggcatat actttgttaa gttatataca
    26341 aaatattata tatgtaattt ttattttaag tgtatataat ttttatttta gtcgttcaat
    26401 aattaaatat ataaataaaa atagagttgt ccaaaagtta aacctcaact tagaacaact
    26461 ctattaacaa tatgtatttt tgttgctttg tattatcttt atttttctaa atttatatta
    26521 ctaaaatctt ttatctttgt atttgctaag acacttttct tagttgattg agaatttttt
    26581 ctatcaaaag tggctttaac ctttgcacct gataagaatt taccagaacc atttatacaa
    26641 ccaccttcac acatcattcc ttctataaaa ttaccttcta gctttcctaa attagccata
    26701 gtcatagttt tcttgatttc tcttgaacca gaaatcttta caggttcaaa attaacacca
    26761 ataccttttt cagcaagata attttctata gcttttgtaa gaccaccagc agctccaaaa
    26821 cctcttccaa aaattgatgc atcatctata tcttcatttg aacacttagc caagtctata
    26881 tcaaatgcct caaataatgc cattatttct tcaaaagtaa gtacataatc aacagctcct
    26941 tttaattctt tcttagctgc ctcactcttt ttggctgtac atggtcctat gaatacaact
    27001 ttagcatctg gttcatgact ttttataaat ctaccactag ctatcatagg agacactgta
    27061 gaagatattt ttcctacatg atttgggtat gttttttcta tataaccaac aaatcctgga
    27121 caacaagaat ttgtcataaa agcttctccc ttttccattc tttcagcaaa ttctaagctt
    27181 tcatgaactg taactgcatc tgctccacaa gctgcttcta atacatcaac aaatcctagt
    27241 gattttatag cattttttat ttgaccatat gtaacatttg cttcaacttg acctgttata
    27301 gctggagcta ccaccgcata cattttctct ttttgaacta actttctagc tacaggagct
    27361 atcaaactct tatcagatat tgctccaaat ggacatgctg acatacatgc tccacagttt
    27421 aaacatttat cctcatgtat catagctttc atattttctc tatcaaatcc taaggcatta
    27481 gttggacaaa cactcttaca tggtctaaca acctctgaga tggcatcata ttgacaagct
    27541 tttttacaca ttccacaagc cttacataat tcatgattta tataggccat tcctccgaca
    27601 tgtgttatag ctccaaattt acaagcttct ttacatctat gtgctagaca tcctctacaa
    27661 atatctgtta ctgtaaattc atttattgga caactgtcac atgcagcttc caaaatatat
    27721 ataatttgtt catcttcttc tatatccatt gtatctaaat ctatcttatc ttgacctggt
    27781 tgtaacccca tacttacatt tactctttca gatattatag ctctttcttt ataaacacag
    27841 catctgtatg taggtttctc accctttatt atttcatact gaatattatc cattgcttct
    27901 ctggtaaggt tatcttcttt tccaagtcta gctattgcag ttaaaacatc atgtcttaat
    27961 ttgtgtattt gtgtttcaaa ttgaaacatt ttaataccac ccccgtaaat gattttatac
    28021 gataccatta taacacaata tgtcctttta ttaatatata cataaaatat tatatgttta
    28081 aattttattt tatcgaatat atatagtgtt tttttgtttt attatataat attattgata
    28141 tttctgaaat ttcactattt t
//
LOCUS       DAEORM030000048        27462 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.048, whole genome shotgun sequence.
ACCESSION   DAEORM030000048 DAEORM030000000
VERSION     DAEORM030000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 27462)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27462)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 27462)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27462
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.048"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            complement(150..344)
                     /locus_tag="KRH23_002740"
     CDS             complement(150..344)
                     /locus_tag="KRH23_002740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226018.1"
                     /translation="MFQVINFLCLFCVGFLVLDVMIYFCKDAMDIFEGTTNVNKVKSI
                     NVWADRVRANSYSYENKIAK"
     gene            complement(653..2182)
                     /gene="lysS"
                     /locus_tag="KRH23_002741"
     CDS             complement(653..2182)
                     /gene="lysS"
                     /locus_tag="KRH23_002741"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004824 - lysine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006430 - lysyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HHS5226019.1"
                     /translation="MKNNQQSNEEAQIQEDLSEVLQVRRDKLKKLQESGRDPFKESRY
                     DRTHYSMDIKDNFDSLEGKTTKIAGRIMSKRIQGKAGFIDIQDQEGRIQSYVRLDAIG
                     EEEYSVFSTYDIGDIVGIEGEIFKTKKGEISVKAKSVVLLCKSLQVLPEKYHGLKDQE
                     LRYRQRYVDLIVNPEVKNAFLIRTKALKALRAYLDDRGFLEVETPILNTIAGGANARP
                     FITNHNTLHIPMYLRIANELYLKRLIVGGFDKVYEMGRMFRNEGMDLKHNPEYTAIEL
                     YQAYADYTDMMEITENVIAHMAEVATGSMIVNYQGTEINFTPPWKRMSMEDCVKEYSG
                     VDFSTINTDEEALEVAREKGIEIKPGMRRGEVINAFFEEFGEDKLIQPTFITHHPVEV
                     SPLSKRNVEDPRRTDRFEAFANKWELANAFSELNDPIDQKGRFIDQLRKRELGDDEAF
                     EMDEDFLKALEVGLPPTGGLGIGIDRVIMLLTNSPSIRDVLLFPTMKPIDNNPNKEEE
                     N"
     gene            complement(2197..2676)
                     /gene="greA"
                     /locus_tag="KRH23_002742"
     CDS             complement(2197..2676)
                     /gene="greA"
                     /locus_tag="KRH23_002742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0070063 - RNA polymerase binding [Evidence
                     IEA];
                     GO_process: GO:0032784 - regulation of DNA-templated
                     transcription elongation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HHS5226020.1"
                     /translation="MEENKEFLLTQEGYDKLEEELENLKVVKRKEVAERIKVAISFGD
                     LSENAEYDEAKKEQAQVEERILKLENMVRKAVIIDESKIDLNVVTIGSIVKVKDLEFD
                     EEVEYTIVGSTEADPYDGKISNESPVGKALLGRAAKEVVEVQVPDGVAKFEILEIRR"
     gene            complement(2785..3753)
                     /gene="dusB"
                     /locus_tag="KRH23_002743"
     CDS             complement(2785..3753)
                     /gene="dusB"
                     /locus_tag="KRH23_002743"
                     /EC_number="1.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0017150 - tRNA dihydrouridine synthase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HHS5226021.1"
                     /translation="MKIGNLELKNKVFLSPMAGVTDLPFRLICKEQGCGLLYTEMING
                     KALCYDDENTKKMLKIEEEEHPVAVQIFGSEPEFMGRAAEIMNDYSNEILDINMGCPA
                     PKVVKNGDGSALMKNPKLAEEVLRAVVKNSKKPVTLKIRKGWDDNSVNAVEIAKIAED
                     CGISALAIHGRTREQFYTGKADWDIIAEIKKNLSIPVIGNGDVFTIEDSINMLDKTGC
                     DAIMIGRGAQGNPWIFKRINHYMNTGEILPEPTLNEKISTAIKHLKLAVEEHGEYVAV
                     REMRKHIAWYLKGLRNSAKLRDEINKIEDYQEVVSKLEYYMEDSLT"
     gene            complement(3890..4660)
                     /locus_tag="KRH23_002744"
     CDS             complement(3890..4660)
                     /locus_tag="KRH23_002744"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004594 - pantothenate kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type III pantothenate kinase"
                     /protein_id="HHS5226022.1"
                     /translation="MLLVFDVGNTNMVLGIYKGDKLVNYWRIKTDREKTSDEYGILIS
                     NLFDYDNVNISDIDDVIISSVVPNVMHSLENFCIKYCKKQPLIVGPGIKTGLNIKYDN
                     PKQVGADRIVNAVAGIEKYGAPSILVDFGTATTFCAISEKGEYLGGTIAPGIKISSEA
                     LFQSASKLPRVELAKPGMTICKSTVSAMQSGIIYGYVGLVDKIISMMKKELNCDDVKV
                     IATGGLAKLIASETKSIDYVDGFLTLEGLRIIYEKNQE"
     gene            complement(4679..5269)
                     /locus_tag="KRH23_002745"
     CDS             complement(4679..5269)
                     /locus_tag="KRH23_002745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HHS5226023.1"
                     /translation="MMNTSASVRKVNVRKMTIIGVLSAISIMLSMTPLGFIPVGPTKA
                     TIMHIPVIIGAIMEGPIVGAAIGFIFGISSLLNAITNPTVTSFVFINPLVSILPRVMI
                     GVLAYYVYQLIIKATNKVYISGLITGAIGSLLNTAGVLGMIYVLYADKYLHAMGKSGS
                     AGKVIMALAAANGVPEAIVGALVVAAVATVLKKSKK"
     gene            complement(5453..6421)
                     /locus_tag="KRH23_002746"
     CDS             complement(5453..6421)
                     /locus_tag="KRH23_002746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P1 family peptidase"
                     /protein_id="HHS5226024.1"
                     /translation="MYNNILDIEGLKVGQVEDRNGLTGCTVVICEEGATCGVDVRGSA
                     PGTRETDLLDPVNMVQKVHAVVLAGGSAYGLESTCGVSRYLEEKGIGFDVGVGKVPIV
                     VGAVLFDLGVGSFKCRPDLKMGYRACEVANTDILNQGNYGAGCGATVGKIRGQEYAMK
                     GGIGSYSIKLDNGLVVSALIAVNALGDVYENGKVIAGALNDKKTETIDTYKLMKQGES
                     KGGFSVDNTTIGIIATNAKLTKAGCKKISQMGHDGYAKSIFPIHTPHDGDTIFTISTG
                     EIEADITLVGSLAVEVVEKSIINAVKKADSVENIMAYKDIVKKREI"
     gene            complement(6414..7391)
                     /locus_tag="KRH23_002747"
     CDS             complement(6414..7391)
                     /locus_tag="KRH23_002747"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004077 - biotin--[biotin carboxyl-carrier
                     protein] ligase activity [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HHS5226025.1"
                     /translation="MRDKIIEIILNNKSEFISGEELSKQLGVSRAAIWKHMKALKEEG
                     YNIESVNKKGYRLAENPTDLLSPQNIYYKLDTEFIGKNIEHLDTIDSTNEHAKRIAIN
                     SVDGTVILSEHQDMGKGRLGRRWDSKPHEGIWMSIILKPDMEPFKAPFITLIAGASVT
                     KALNNLGANTLIKWPNDVILNGKKICGILTELSAEIERTNYVVLGIGINVKIMDFEQE
                     IADKATSLYKEGYMLSRVDIVRNVLTEFEKLYLDYTVNNSKEKTLKICRDYSAIIDKN
                     IYVLKGDNRELVKCLDINEEGNLLVQRSDGSIKEIISGEVSIRGEKGYV"
     gene            complement(7706..9676)
                     /gene="ftsH"
                     /locus_tag="KRH23_002748"
     CDS             complement(7706..9676)
                     /gene="ftsH"
                     /locus_tag="KRH23_002748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HHS5226026.1"
                     /translation="MNKLLKGAGFYLLVFIIIVGIVQFSGKPTEKIKDLKFSEVYREL
                     TDENISRLYFVNQTSVEGTIKDTNTKFKSYVPTEVMGNKLADEVLDQAKAGKLTFGGE
                     AKPSTPWFVEMLPTLLLIFFMVIIWFVFMNQSQGGGGKVMSFGKSKAKVHKDDEKTRV
                     TFKDVAGLDEEKEDLQEVVDFLKNPKKYIELGARIPKGMLMVGPPGTGKTYLSRAVAG
                     EAGVPFFSISGSDFVEMFVGVGASRVRDLFEQAKKSAPAIIFIDEIDAVGRKRGAGLG
                     GGHDEREQTLNQLLVEMDGFGVNQGIIIMAATNRPDILDPALLRPGRFDRQVVVGTPD
                     VKGREAIFKVHSRNKPLSDDVKMDVLARRTPGFTPADIENLMNEAAILTARKREKKIK
                     METIEEAITKVIAGVAKKSKVISEKERRLTAYHEGGHAVCAHVLEEVSPVHQVTIVPR
                     GRAGGFTMQLPVEDKFYATKNEMKENIVVLLGGRVAEELVLKDVSTGASNDLERVTAT
                     ARSMVTKYGMSSKLGPMSFDSDDEVFLGNSFSSKRNYSEEVAFEIDQETKRIVDGAYD
                     KTRSILQENMDRLEYVAQALLIYETLDAEQFVKAFNKELPLNEIENEVTEENSSKEVE
                     EQLTIKLEKDEEERNNVIDINKNLEDKSDKDK"
     gene            complement(9710..11098)
                     /gene="tilS"
                     /locus_tag="KRH23_002749"
     CDS             complement(9710..11098)
                     /gene="tilS"
                     /locus_tag="KRH23_002749"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016879 - ligase activity, forming
                     carbon-nitrogen bonds [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HHS5226027.1"
                     /translation="MIFDKVLSTINKHNLIQKGDKIVLGLSGGPDSVCLLHVLNRLKK
                     DFNIEIYAAHLNHQIRGIEAQKDALYVSKLCEDMGIIFFVKSINVPKYCENEGLSLEE
                     GARKLRYEMFYEIKDKIKANKIAIGHNLNDQAETVMMRIMRGTGLKGLKGIDYIRDNC
                     IIRPILDVERNEIEEYCEAYNLNPRIDKTNLENIYTRNKIRLDLLPYMKDNFNSNVIE
                     SIVRMSNSLKSDNDYIEKEAEAKFREVSNIKEKGFVEINLDDFVCLHDAIKVRVLRNS
                     IKHILGDTNFVDQRHIEDIMSLEDNSKVNKMLTLPRNIFVYRKKDSIILTNEEIVNEE
                     IEFYYNVPSNGFIKIKELKQIIETQVMSIDRYKSMKLDNSSKGFDFNKVKGGIVIRSR
                     RQGDKIKLAMGSKKVKDLFIDLKIPREERCKIPIITDSEGIICVGDYKISENYKIDEN
                     TKEVLKINFNKL"
     gene            complement(11281..11709)
                     /locus_tag="KRH23_002750"
     CDS             complement(11281..11709)
                     /locus_tag="KRH23_002750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HHS5226028.1"
                     /translation="MEEKSLSVKISINTRQYDEKGNMDTIEMTAFGKIFYKNDGIYVI
                     YKEKEENIEITNTIKILKNQVSIKKFGAINSTMLFKCGESSTTKYVTPQGTLLIDIDT
                     RELDINIQEGEHIKLKIDYNIKVQDLFLGRNKIDIYIGTK"
     gene            complement(11726..12532)
                     /gene="murI"
                     /locus_tag="KRH23_002751"
     CDS             complement(11726..12532)
                     /gene="murI"
                     /locus_tag="KRH23_002751"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008881 - glutamate racemase activity
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HHS5226029.1"
                     /translation="MNNKPIGVFDSGLGGLTVLKEIMKILPNEDIIYFGDTARIPYGS
                     RSKETIIKYTFQAINFLKTKGVKAIVIACNTATARSLKEAQEKYDIPIIGVIEAGART
                     AVSSTKNKIVGIIGTEGTISSKAYNLEISKIDESIEIVNKACPLFVPIVEEGWANTEV
                     AKLTAKIYLQELKEKNIDSLVLGCTHYPILKRTIGEEVGEHIKLVNPAKETAKDLKKI
                     LEVQNIINNTEIHGTYQYYVSDIPEKFSDIAREFLKKKIDKIQKVEIQKY"
     gene            complement(12734..13219)
                     /locus_tag="KRH23_002752"
     CDS             complement(12734..13219)
                     /locus_tag="KRH23_002752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0030435 - sporulation resulting in
                     formation of a cellular spore [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase"
                     /protein_id="HHS5226030.1"
                     /translation="MATLLALTFIFMPIKEVFAYEPTENIKKVNKQEKNIAKKEVINL
                     SDNDLMLLSKLVAGEARGESYEGQVAVAAVVINRVLDPRFPDTIEEVIYQKNAFSVVL
                     DGSIKMAPTDSARKAAQEALYGTDPTNKAVYFWNPEIATCKWINRLNPYMRIGNHVFA
                     K"
     gene            complement(13270..13929)
                     /gene="spoIIR"
                     /locus_tag="KRH23_002753"
     CDS             complement(13270..13929)
                     /gene="spoIIR"
                     /locus_tag="KRH23_002753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein R"
                     /protein_id="HHS5226031.1"
                     /translation="MRKIKIRLGLLILSLISVISIMTIVINGEVKKVDNISKDYKDKL
                     IRFHVIANSNTDEDQELKLKVRDEVIKYLQPKLQNSKSIKESEAIIKKEYSSLEEISK
                     NIILKNGYNYSVKVGIQYSNFPTKQYSNIVLPAGEYKALKIIIGKGEGKNWWCVMFPP
                     LCFVDESNGVIDKSTDDKLKEVLTDKEYKLIKQDTPKKTSRVKIKFKVLEVVKDLEKK
                     F"
     gene            complement(14074..14754)
                     /locus_tag="KRH23_002754"
     CDS             complement(14074..14754)
                     /locus_tag="KRH23_002754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HHS5226032.1"
                     /translation="MENLTKLNLDNYKPLRDVVFENLREAILEGKLKPGQRLMEVQLA
                     EQLGVSRTPVREAIRKLELEGLVVMLPRKGAYVANMSLKDIMDVLEVRASLEGLAAYL
                     AAERISDEDIKKLKDISEEFKKSTLESDVDALLKLDVEFHECIFKATNNKKLIQLINS
                     LWEQVYRFRVTYMSAYDTSHNIVEEHKYLLDAIIKGDSELSKKYATEHIEKAEQFMID
                     KAMISKDL"
     gene            complement(14738..15628)
                     /gene="ispE"
                     /locus_tag="KRH23_002755"
     CDS             complement(14738..15628)
                     /gene="ispE"
                     /locus_tag="KRH23_002755"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050515 - 4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase activity
                     [Evidence IEA];
                     GO_process: GO:0016114 - terpenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HHS5226033.1"
                     /translation="MDFIRLKSRAKINLSIDVLGKRQDGYHFVEMIMQTIDLYDIVKI
                     KELDEDEIKVKSTSLDIPLDEDNIVYKAAKILKNKFYIKKGVEIFIEKNIPVAAGMAG
                     GSSNAAAVLVGLNHLWELRLSEDELKEIGLNLGADVPFCISGRPALAQGIGEKLTNIK
                     GLPCDTNILICKPDLFVSTKEVYQGLDLNNIKKRPNNKYLIECLKSEDIKAVSESMVN
                     ILENVTIGKHKEISDIKQVMMKNNALGSMMSGSGPTVFGLFKNKEDALIGKKELLKKY
                     KQVYVVNSSQKGVEICGEFN"
     gene            complement(15746..17296)
                     /locus_tag="KRH23_002756"
     CDS             complement(15746..17296)
                     /locus_tag="KRH23_002756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3794 and LysM peptidoglycan-binding
                     domain-containing protein"
                     /protein_id="HHS5226034.1"
                     /translation="MELIKDVIKVDNRIDFGKFQTFIEAEAVVPDKKLDVYEIVKTEG
                     YISLKKIEMADGKILCRGSFNYNVIYIADDKNTISNVDGKVDINEVIEKDNVIQDMEY
                     MLFSEVEHMDCTIMNERKIKVGALMNIRGSLFEKQRLDIVKDVAQVEGIQKHRKEICF
                     QDIVGIEKAESSIRDTITINTEEIQSIISLNPCVKVKESRVTDNKVIIGGVLEINPLA
                     CTYEGELVELDRVGIEFTQFVEVPGVSDGMTEEVLLSMSDFNHIFKQNSESNTGLLEI
                     DCMACCKVKVTDEVTREVLQDAYSPQKIIKFDHKPIQLNKTLRRSEETFMVREGIRND
                     NDDIQIKDIVSVCPTMSIENSYIEGNKSIIQGIIKVEILFVPVEGLKLVYKISEEIPF
                     EHDIEMDNLTDTASVFNTACIDKVEVDLNRDQIDLIIKIKRFTEALDKKAENFIIKGE
                     DQGVYDLSKAPSIIVYICKEGDTFWNIAKKYNTTENEIAELNDIKLDEPIKPGKCLIL
                     EKKVVLVD"
     gene            complement(17390..17656)
                     /locus_tag="KRH23_002757"
     CDS             complement(17390..17656)
                     /locus_tag="KRH23_002757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HHS5226035.1"
                     /translation="MATVQTLDKIRVSLERHIGKKILLKANKGRKQIITKEGILEKVY
                     PSVFVIKLDDESNGYPRVSYSYSDLLTSNVKLQVFRDQDKLQIS"
     gene            complement(17804..18664)
                     /gene="yabG"
                     /locus_tag="KRH23_002758"
     CDS             complement(17804..18664)
                     /gene="yabG"
                     /locus_tag="KRH23_002758"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation peptidase YabG"
                     /protein_id="HHS5226036.1"
                     /translation="MKVGDIVARKSHNKDIVFKIVSFGVDENNEKIAILKGIAFRVIA
                     DAYIDDLELVKAPDIKDILIDKNVENLLYKSVRKAKERQKRMTRAVPKLQLNPNTYGM
                     PGKVLQIDGDKEYLKICLDVYAQLGIPAVGVAVSEQNQYKEVRALLEKYNPDILVITG
                     HDAMTIKRGDIEDMSNYRNSSNFVKTVKEARKWQPNLDNLVIFAGACQSNYEKIISAG
                     ANYASSPGRIMIHALDPVFIVEKIACSRIDVVVPIDEVIEQTITGVKGIGGSETRGKF
                     RWAMPKTILH"
     gene            complement(18748..19686)
                     /locus_tag="KRH23_002759"
     CDS             complement(18748..19686)
                     /locus_tag="KRH23_002759"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0070573 - metallodipeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HHS5226037.1"
                     /translation="MKFIDLHCDTIAKLMENVETSELKSNKYSVDIDRLKKGDSLAQT
                     FALFVDTEEVKHPFDYCMSMANKFHEEMKKNSDEIVLATNYEEIMKNQSEGKLTALLS
                     IEEGAVLEGKLENLKKFYDLGVRMMTISWNHVNELSFPHNKVEYREKGLTDFGREVVH
                     KMNELGMLVDVSHISDGGFYEIAKISSKPIIATHSNSRAMMNHSRNLTDDMIKVLANK
                     GGVTGINFFHLFLSDKSESKLEDMVRHIKHIVNVGGIDVVSLGSDFDGIDSKVEIEDI
                     SQMGKLYEPLKKEGFSEDDIEKIYYKNALRVIKEVL"
     gene            complement(19796..19957)
                     /locus_tag="KRH23_002760"
     CDS             complement(19796..19957)
                     /locus_tag="KRH23_002760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226038.1"
                     /translation="MFILRFADDDDNLSVKDFTSLTDLKKYISENNIDKTWHQIEEVK
                     KVIPNLKEE"
     gene            complement(19967..20464)
                     /locus_tag="KRH23_002761"
     CDS             complement(19967..20464)
                     /locus_tag="KRH23_002761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SEC-C metal-binding domain-containing protein"
                     /protein_id="HHS5226039.1"
                     /translation="MSLYTEWRNLSDNHESQEAEVKFWEEYLKVEAGIYNEILNNKMD
                     VVEGKVSELAEKFGTTNEFFMGFIDGISESLKEDIVLEEVEADKEVSIKIDWEKLYNN
                     MVTVEAHWLYNLQGWEDILPADQRKEIIKAYKKSKTIVKEAKIGRNDSCPCGSGKKYK
                     KCCGK"
     gene            complement(20579..21289)
                     /locus_tag="KRH23_002762"
     CDS             complement(20579..21289)
                     /locus_tag="KRH23_002762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0489 family protein"
                     /protein_id="HHS5226040.1"
                     /translation="MENYEYSGFYIEKPVGNNVFSYDKRENKSIYVPKLINGTLNDVR
                     LGNEVVFNEVDENKEIKAKGLENMVEYVLGNKKIYVFDNHNHAFYFWAKSLLKGEFTK
                     GCKLVHVDQHKDTREPENYDVDVNNLKDVFRYTNEVLNVGSFIKPALKYNIFSELIII
                     DSLYGFDLEVESEFVLDIDLDIFSSDMDYIPFELKFYKIKNLIKKAKVITIATSPYFI
                     NQEYAIKVLKELFNYDII"
     gene            complement(21465..21995)
                     /locus_tag="KRH23_002763"
     CDS             complement(21465..21995)
                     /locus_tag="KRH23_002763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226041.1"
                     /translation="MDIRALPIRITKEEAIEIAKSGKNSLFSKLILKNKYAHEVRLHY
                     IEFKIITLKIHKTKSIFKNRRYSNDINELKILVNGSTGSGSIVQDFPTYEVVKNVDCN
                     IVQYSDKDERRVKAKANKMAMRLTHRFMGGIPEIEIVKIESIFRPYWVVFFGKVELNR
                     RVSYLPIEADGFVIGM"
     gene            complement(22012..22242)
                     /locus_tag="KRH23_002764"
     CDS             complement(22012..22242)
                     /locus_tag="KRH23_002764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226042.1"
                     /translation="MSKLVSKVKKDLEIKWLGIDGFLVLLYFLITGFIFYGILTRNDI
                     IVGKIIPYGVMAVVIVIFFDYIYRVLKMTRKK"
     gene            complement(22257..23651)
                     /locus_tag="KRH23_002765"
     CDS             complement(22257..23651)
                     /locus_tag="KRH23_002765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter family protein"
                     /protein_id="HHS5226043.1"
                     /translation="MLTFWENGIIVIFAFILLGIGYYFSRNVKDMESYYLGNRSLPWS
                     LIVGTLVASWYGGVGTVGSVEYAAIYGISAWAVWSIAAHIGRMPLALWVGPRIHIRTN
                     ITVPDLLESFYGKHVAIIGAILMFIYCAQLGEITAMGTIGNVAWKIDKELIGLIMVGV
                     VVVLTVLGGLMGVAITDMVLFFCMVFGLTMVMPGQFEQIGGFQGLTEALKDAPQLMHP
                     TKGMSAMKALMLIVYSFGAYSDPTFYQRFSAADSPKVGRRALLTCFSLWICFDMVLTM
                     TGLIVRATYPEMAPAAGYITLVLDTLPQGIRVIFIIGILGSIISTLDSYYLAAGATLA
                     NDIYGRITKKELSQKQLVKFTRIGVCLAAVMGLSVAFRFENVYDACIFVGSIWMGSAF
                     VPIVGGLLGNGRRTSMGGILGMIVGGVTFGYFKIFPVQSFELEPLVIAIPFSFIAWMI
                     GNRIGENLNTQNNL"
     gene            complement(23777..25030)
                     /locus_tag="KRH23_002766"
     CDS             complement(23777..25030)
                     /locus_tag="KRH23_002766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015112 - nitrate transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HHS5226044.1"
                     /translation="MESKNNVKRFLIIFILAFGTTAMYSLPYMKSSFYDPMQQALALS
                     HTQIGNLLSLYGLVGMVSYFIGGWFADRFSVRKLITFSLIASGILGFYFSTFPSYSMI
                     LLIFVLWGFTTILTFFSASVKVVRMQGSESEQGRIFGFYEGLSGVSGTLISFIGLYFF
                     GKFAEITVGFKYVVWLYSAASIICGILLFFLVEEKKDSGASDEGLSIKSLLKVVTMPK
                     AWLIGLIIFSTYLVFSSLTYLSPYLSEVYVMPMTLVSALSIIRTYVIKMGASPVAGVI
                     TDKVGSSIRVMFVGFILMTVSTAAYLVIPKSTGFIWIAVINMIILSVILFGFRGIYFA
                     SVSESNISLETTGAVVGFASFIGFSPDAFYYTIAGNWLDKYGQTGYTYIFILSVVCAV
                     IGIFATYALNKINKRENKGLNNKIA"
     gene            complement(25081..26235)
                     /locus_tag="KRH23_002767"
     CDS             complement(25081..26235)
                     /locus_tag="KRH23_002767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016846 - carbon-sulfur lyase activity
                     [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0019346 - transsulfuration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trans-sulfuration enzyme family protein"
                     /protein_id="HHS5226045.1"
                     /translation="MSNNINQDLETKIIHWGHSADPTTGALATPICQTATFAAKTVEH
                     FEELCMTWGYVYTRECNPTLTELEAKLAMLENAESAISSTSGMGAITSTILALVKSGD
                     HIVSSDGIFSHTKLFMSELLSKFGVEVTFVDAVNPQNVKEAMRPNTKIVYIESPLNPS
                     LDLVDIKTIAEIAHENKSLAIVDSTFGTPIVQRPIDLGADLVIHSLTKFINGHGDTLG
                     GAVAGSKELIDLVRWPSLCCFTGASLPPMSAWMILRGMKTLDMRMKKHCENGLAVAEF
                     LEEEENVELVKYPALKSHPQYELCKTQMNGLGGGVVSFKLKDGINGLTRDQASRRLMN
                     SLELATIATSLGEEHTLVQMNGENLIRIAVGLESSNDIINDFKQAIKKLK"
     gene            complement(26795..27304)
                     /locus_tag="KRH23_002768"
     CDS             complement(26795..27304)
                     /locus_tag="KRH23_002768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HHS5226046.1"
                     /translation="MYQQQQEILNKYNDAKIIKETYTGTTTNRPKFEKIISSLKKGDL
                     LVATKLDRLARSTSEGIQLIEGLFAKEVSVHILNIGLLENTSMGKFFLTTLLAVAELE
                     RNMIIERTQLGKEFAKKKKDFKDGRPKKYSNQQIQYALGLLNSKPYREVVKMTGISKS
                     TLIRAKKSI"
BASE COUNT         8426 a         5279 c         2721 g        11036 t
ORIGIN      
        1 actatatcac cttaaaaata attcgtcaat actttttttg ttttttattt taaaaaaggt
       61 tataactttt ggttttttta ataaatataa ttaaaactaa tagatataac ccttgatatt
      121 acaaacaata catgcatata taattttacc tattttgcaa ttttattttc ataagaatat
      181 gaattagctc tcactctatc tgcccaaaca tttatactct taactttatt aacattagtt
      241 gtaccctcaa aaatatccat tgcatcctta caaaaatata tcataacatc aagaaccaaa
      301 aatccaacac aaaataaaca taaaaaatta attacttgaa acatcagaca ttcccccaat
      361 aattttttat atatagtatt ctcataaatt attcttttta ccttctcata aattattcta
      421 aatattttca taataaatta ctttcaatca tattttctaa atataaagtc tcaatcaaca
      481 aaaactaata tcaatttcta acgtttgttg gtaatttata aattaaatat ctaaaagaat
      541 ctttgaagca tataaaaagc attctacact gacattttaa ataaaattta gctatttatt
      601 gataatttaa tagctaaact ttatttaaaa cttagtagaa tgctaatatt tcttagtttt
      661 cttcttcttt atttggattg ttatcaatag gtttcatagt tgggaataat aatacatctc
      721 ttatagatgg agagttagtt aataacataa ttactctatc tatacctatt cctagtcctc
      781 ctgtaggagg tagacctacc tctaatgctt ttaagaaatc ttcatccatt tcaaaagctt
      841 catcatcacc taattctctt tttcttaatt ggtctataaa tcttcctttt tggtcaatag
      901 ggtcattaag ttcagaaaat gcattagcta actcccactt attagcaaat gcctcaaatc
      961 tatcagttct tcttgggtct tcaacatttc tcttagataa tggagatact tcaactggat
     1021 gatgagttat aaatgttggt tggattaatt tatcttctcc aaattcttca aagaaagcat
     1081 ttattacttc tcctcttctc attccaggtt ttatctctat acctttttct ctagcaactt
     1141 ctagtgcctc ttcatctgta tttatagtag aaaaatctac accagaatat tctttaacac
     1201 aatcttccat actcattctt ttccaaggtg gtgtaaagtt tatttctgtt ccttgatagt
     1261 taactatcat acttcctgta gcaacttcag ccatatgtgc aataacattt tctgttattt
     1321 ccatcatatc agtatagtct gcatatgctt gatataattc tattgcagta tattcaggat
     1381 tatgttttaa atccatacct tcatttctaa acattcttcc catttcataa actttatcaa
     1441 atccaccaac aataagtctt tttaaataca attcattcgc tattcttaaa tacattggta
     1501 tatgtaaagt attatgatta gttataaatg gtctagcatt tgccccacct gctatagtat
     1561 ttaatattgg agtctcaact tctaaaaatc ctctatcatc taagtatgct cttaatgctt
     1621 ttaatgcttt tgttctaatt aaaaaagcat tttttacttc tggatttact attaagtcaa
     1681 catatctttg tctatatctt agttcttggt cttttaatcc atgatatttt tctggtaaaa
     1741 cttgtaaaga tttacatagt aatactacag atttagcctt tacagatatt tcaccttttt
     1801 tagttttaaa gatttctcct tcaattccaa ctatatctcc aatatcatat gttgaaaata
     1861 cactatattc ttcctctcct atagcatcta gtcttacata agattggatt cttccctctt
     1921 ggtcttgaat atctataaag ccagctttcc cttgtattct cttgctcatt atacgtcctg
     1981 ctatttttgt agttttaccc tcaagagaat caaagttatc ttttatatcc atagaataat
     2041 gagttctatc atatctactt tctttaaaag gatctctacc tgactcttgt aattttttta
     2101 gtttatctct tcttacttga agtacttcac taaggtcttc ttgaatttgc gcttcttcat
     2161 tgctttgttg attatttttc atttttttcc tccaaattat cttcttattt ctaatatttc
     2221 aaacttagca actccatcag gaacttgcac ttccacaact tctttcgcag ctctacctaa
     2281 aagtgctttc cctacaggag attcgtttga tattttacca tcatatgggt ctgcttctgt
     2341 cgaaccaact atagtatatt caacctcttc atcaaattct aaatccttaa ctttaactat
     2401 tgatcctatt gtaacaacat taaggtctat tttgctttca tctatgataa cagcttttct
     2461 aaccatattt tctaatttta aaattctttc ttcaacttgt gcttgttcct ttttagcttc
     2521 atcatactca gcattttcag ataaatcacc aaaagatata gcaactttta ttctctctgc
     2581 aacttctttt ctctttacaa cctttaagtt ttctaattct tcttctaatt tatcatatcc
     2641 ctcttgtgtc aataaaaact ctttattttc ttccattata aatacaactc cttcacaaat
     2701 ttcttaggaa ttttcctaat tatattttaa aaattttata atcttttttt aatttatgcg
     2761 ctatattata agtcactatt atttttatgt caaggagtct tccatatagt actccaattt
     2821 cgacacaact tcttgatagt cttctatttt gttaatttca tcccttaatt ttgcagagtt
     2881 tctaagtcct tttaaatacc aagcgatgtg ttttctcatt tcccttacag ctacatactc
     2941 tccatgttct tctactgcaa gttttaaatg cttaatggca gtacttattt tttcgttaag
     3001 agttggctct ggcaaaatct cgcctgtatt catataatgg tttattcttt taaatatcca
     3061 agggttacct tgagcacccc tacctatcat tatagcatca caaccagttt tgtctaacat
     3121 atttattgaa tcttctattg taaatacatc accatttcct ataacaggta tactcaaatt
     3181 tttcttaatc tctgcaatta tatcccagtc tgctttgcct gtataaaact gttctctagt
     3241 tcttccatgt attgctaaag cgcttattcc acaatcctct gctatctttg ctatttcaac
     3301 agcatttaca ctattatcat cccagccttt tcgaatcttt aaagtcactg gcttttttga
     3361 gttcttcact actgccctca atacctcttc tgcaagctta ggatttttca taagtgctga
     3421 gccatctcca tttttaacta cttttggagc tggacacccc atatttatat cgagaatctc
     3481 atttgaataa tcattcatta tctctgctgc tcttcccata aactctggtt ctgaaccgaa
     3541 tatctgaact gctacaggat gttcttcctc ttctatctta agcatttttt tagtattttc
     3601 atcatcatag caaagtgcct taccatttat catttctgta tataaaagcc cacatccctg
     3661 ttctttacaa attaatctaa atggaaggtc tgttacacct gccataggtg atagaaaaac
     3721 tttatttttc aattctaaat ttcctatttt cattgttttt ctcctatttt tgcctttatt
     3781 ttgtgattta actttaaatt cttatttcct cattataata taccacatat agctagaaat
     3841 ctatcataaa aagggaattg gatatataac ccaattccct gtatattaat tattcttggt
     3901 ttttttcata tattattctc aatccttcta gtgttaaaaa accatctaca taatctatac
     3961 ttttcgtctc tgaagcaatc agtttagcta atccacctgt agctataacc ttaacatcat
     4021 cacaattcaa ttctttcttc atcatactta ttattttgtc aactaaacca acatatccat
     4081 aaattattcc agattgcatg gctgatacag tactcttaca aatagtcata cctggcttag
     4141 ctaattctac tctaggtaat ttagacgcac tttgaaataa cgcctcacta gatattttta
     4201 ttcctggtgc tattgttcca cccaaatatt cacctttttc agagatagca caaaatgtag
     4261 ttgctgttcc aaaatcaaca agtatacttg gtgctccata cttttctatc cctgctacag
     4321 cattaactat tctatctgcc ccaacttgtt ttggattatc atattttata tttagacctg
     4381 tttttatgcc tggacctact attaatggct gttttttaca gtactttata caaaagtttt
     4441 caagagaatg cataacattc ggaactacag atgatattat aacatcatca atatcactta
     4501 tattcacatt atcataatca aataggttac ttatcaggat tccatattca tcagacgttt
     4561 tttctctatc tgttttaatt ctccagtaat taactaattt gtcaccttta tatataccta
     4621 aaaccatatt agtatttcca acatcaaata ctagaagcat atgtcattaa ccttctttct
     4681 attttttgct tttcttaagt acagtggcaa cagcagctac tactaaagcc cctactattg
     4741 cttctggcac cccatttgct gcggcaagag ccattattac ttttcctgct gaaccacttt
     4801 tacccattgc atgaagatac ttgtcagcat ataagacata tatcattcct aaaactccag
     4861 ctgtatttaa cagagaacct attgcccctg taattaaacc tgatatgtat accttatttg
     4921 tagccttaat tattaactga tatacataat aagctaatac acctatcata actcttggta
     4981 atattgaaac taatggattt ataaaaacaa aagatgttac tgttgggttt gttatagcat
     5041 ttaagagact tgatatccca aatataaatc ctattgctgc cccaactatt ggtccttcca
     5101 taatagctcc aataataact ggtatgtgca ttatagttgc ttttgtaggt ccaactggaa
     5161 taaatcccaa tggagtcata gatagcataa tagaaatagc tgatagtact cctattatag
     5221 tcatctttct tacatttact tttcttactg atgcacttgt gttcatcata aaaaatacac
     5281 ctccgttcca gctcattaag atgccggact acttaatttt ttaatttttt tcgttttttt
     5341 cttataacta tgagtcaagc taccattgta ggatgcccgc tctaacaaga ataattttat
     5401 caagatgagt tgccattgtc aacaatttga caagaaaaat atgctaattt catcatattt
     5461 ctcgtttttt tactatatct ttatatgcca ttatattttc tacactatcc gcttttttta
     5521 ctgcatttat tatacttttt tccacaacct ctacagccaa tgaacctact aatgttatat
     5581 ctgcttctat ttctcctgtt gatattgtga atattgtatc tccatcatga ggtgtatgga
     5641 taggaaaaat agacttagca tatccatcat gtcccatttg agatatcttt ttacatccag
     5701 ctttggttaa cttagcattt gttgcaatta tcccaattgt agtattatct acactaaatc
     5761 cacctttact ttcaccttgt ttcattaatt tatatgtatc aattgtttct gtctttttat
     5821 catttaaagc accagctata accttaccat tttcataaac atctccaaga gcatttacag
     5881 caattaatgc agatacaact agaccattat ctaattttat agaatagcta cctattccgc
     5941 ctttcatagc atattcctga cctcttatct ttccaacagt ggctccacaa cctgctccat
     6001 aatttccttg atttaaaata tcagtatttg caacttcaca agctctataa cccatcttta
     6061 aatctggtct acatttaaag ctccctactc ctaaatcaaa taaaactgct cctacaacta
     6121 taggcacttt acctacacct acatcaaagc caattccttt ttcttctaag tatctactta
     6181 caccacaagt ggattcaaga ccatatgcag aacctccagc caaaactact gcatgaactt
     6241 tttgaaccat atttacaggg tctaataaat cggtttctct agtacctgga gcagagcccc
     6301 ttacatcaac accgcaagta gctccttctt cacatattac tactgtgcac ccagtaagac
     6361 catttctatc ctcaacctgc ccaaccttta agccttctat atccaaaata ttattataca
     6421 tatccttttt ctcctcttat agaaacttca cctgaaataa tttcttttat acttccatca
     6481 cttctttgaa ctaataaatt tccctcttca tttatgtcta aacatttcac tagttctcta
     6541 ttatctcctt ttaatacata tatattttta tctataattg cagaataatc tctacatatt
     6601 tttaaggttt tttctttgga attatttaca gtataatcta aatataattt ttcaaattca
     6661 gtcaatacat tcctaacaat atctactctg gataacatat atccttcttt atacaatgat
     6721 gtggctttgt cagctatttc ttgttcaaaa tccattattt taacatttat tccaattcca
     6781 agaacaacat aatttgttct ttcaatttca gcagataact ctgttaatat accacatatt
     6841 ttttttccat ttaaaataac atcatttggc cattttatta atgtatttgc tcctagattg
     6901 tttaaagctt tcgttacact tgctcctgct attaaagtta taaatggagc tttgaatggt
     6961 tccatatctg gttttaatat aatactcatc cagattcctt catgaggttt tgaatcccat
     7021 cttcttccca atcgtccttt ccccatatct tgatgttcac ttaaaatcac agtcccatct
     7081 acactattta tagctatcct tttagcatgt tcatttgttg aatctatagt gtcaagatgt
     7141 tcaatatttt ttccaataaa ctctgtatct aatttatagt aaatattctg tgggcttaat
     7201 aaatcagttg gattttccgc taatcgatac ccttttttat ttacagattc tatattatat
     7261 ccctcttctt ttaaggcttt catatgtttc catatagctg cacgtgacac ccctaattgt
     7321 tttgataatt cttctcctga aataaattca gatttattat ttaatataat ctctattatt
     7381 ttatctcgca tatttcacct ctaatatgac ataatttcat gacttatttt cttctaataa
     7441 ataattatac attattaata tacttttaat actattaatt ttaaatttcc tttttaatta
     7501 ttataatggt tgttttatat tttatattga tgctttatat gattttacat tttatttaaa
     7561 taattttaaa ataataaaaa aactgaaagt atcaattaaa ttaatacatg caaatataat
     7621 ttgcttatta atttaatatt atactttcag ttttagtatt taatccacat cagataataa
     7681 tcctaaaatg accaaggtct taaaactatt tatctttatc agatttatct tctaaatttt
     7741 tatttatatc aataacattg tttctttctt cttcatcttt ttctaatttt atagttaatt
     7801 gttcttcaac ttctttagaa gaattttcct ctgtaacttc attttcaatt tcattcagag
     7861 gtaactcttt attaaatgct tttacaaatt gttctgcatc taaagtttca tatataagta
     7921 aagcttgtgc tacatactct aatctatcca tattttcttg taatatactt cttgtcttat
     7981 catatgcacc atcaactata cgctttgttt cttggtctat ctcaaaagca acttcttcag
     8041 aataatttct cttacttgaa aaactattac ctaggaatac ttcatcatca ctgtcaaatg
     8101 acattggacc aagcttagaa ctcattccat actttgttac catacttctt gcagtagctg
     8161 taactctttc taagtcattt gaagcacctg tagatacatc cttaagtact agctcttctg
     8221 ctactctacc accaagtaaa actacaatat tttctttcat ttcatttttt gtagcataga
     8281 acttatcttc aacaggaagt tgcattgtaa accctccagc tcttcctctt ggaactattg
     8341 taacttgatg aacaggactt acttcttcaa gtacatgggc acaaactgca tgccctcctt
     8401 catggtatgc tgtaagtctt ctttctttct cacttattac tttcgatttt ttagccacac
     8461 ctgctataac ctttgttata gcttcttcta tagtttccat cttaattttc ttttctcttt
     8521 ttctagctgt taatattgca gcctcattca ttaagttctc tatatcagca ggagtaaatc
     8581 ctggtgttct tctagccaag acatccattt ttacatcatc acttaatggt ttatttcttg
     8641 agtgaacttt aaatatagcc tctctacctt ttacatctgg tgtaccaaca acaacttgtc
     8701 tgtcaaatct tcctggtcta agtaaagctg ggtcaagtat atctggtcta tttgtagctg
     8761 ccatgattat tataccttga tttaccccaa atccatccat ttcaactaga agttgattaa
     8821 gagtttgctc tctttcatca tgacctccac caagacctgc acctcttttt ctaccaactg
     8881 catcaatttc atctatgaat atgatagctg gagcactttt cttagcctgt tcaaataaat
     8941 ctcttactct tgaagcacca accccaacaa acatctcaac gaaatcagaa ccacttatac
     9001 tgaaaaaggg aactcctgct tctcctgcaa ctgctcttga tagatatgtt ttaccagttc
     9061 caggaggtcc taccataagc attccttttg gtattcttgc acccaattca atatatttct
     9121 taggattctt taagaaatct actacctcct gcaaatcttc tttttcctca tctagtccag
     9181 ctacatcttt aaatgtaact ctagtttttt catcatcttt atgaacctta gcttttgatt
     9241 tgccaaaact cataaccttt ccgcctccac cttgagactg attcataaac acgaaccaaa
     9301 taatcaccat gaagaatatt aacagtaatg taggcaacat ttcgacaaac caaggtgtag
     9361 atggcttagc ttcaccacca aaagttagtt tcccagcctt agcttggtct aacacctcat
     9421 ctgcaagttt atttcccatc acttctgttg gaacatatga cttaaacttt gtatttgtat
     9481 cttttatagt accttctaca gaagtttgat ttacaaagta taatcttgat atattctcat
     9541 ctgttaattc tctatatact tcagagaatt ttaaatcttt tattttttct gtaggcttac
     9601 ctgagaattg aactatacct actataatta taaaaacaag tagataaaaa cctgcccctt
     9661 ttagcaactt attcaatata gaagccctcc tttcatacat tgctttgccc tataatttgt
     9721 taaaattaat ttttaatact tcttttgtgt tttcatcaat tttataattt tcactgattt
     9781 tataatctcc aacacatatt attccttcac tatctgtgat tataggaatt ttacatcttt
     9841 cttctcttgg gatttttaaa tctatgaata aatctttcac ttttttactt cccatagcaa
     9901 gctttatctt atcaccttgc cttctgcttc ttattactat accccctttt accttattaa
     9961 aatcaaaccc tttagatgaa ttgtctaatt tcatactctt atacctatct atgctcatta
    10021 cttgggtctc aataatttgt tttaattctt ttattttaat aaacccatta ctaggtacat
    10081 tgtaataaaa ttcaatttcc tcattaacaa tttcctcatt cgttaatatt atactgtctt
    10141 tttttctata aacaaatata tttcttggaa gagttaacat tttatttact tttgaattat
    10201 cttctaaaga cattatatcc tctatatgtc tttggtcaac aaaattagta tctcctagta
    10261 tatgttttat ggaatttcta agaactctaa ctttgatagc atcatgtaag caaacaaaat
    10321 cgtctaaatt tatctctaca aagccttttt cttttatatt tgaaacttct ctaaatttag
    10381 cttctgcctc tttctcaata taatcgttat cactttttaa actattgctc atcctcacta
    10441 tagattctat tacatttgaa ttaaaattat ccttcatata tggtaaaagg tctaacctta
    10501 tcttatttct agtgtatata ttttctaaat ttgttttatc tatcctcgga tttaaattat
    10561 aagcttcaca atactcctct atctcatttc tttccacgtc taatatgggt ctaattatgc
    10621 aattatctct aatataatca attcccttta agccttttaa acctgttcct ctcatgatac
    10681 gcatcataac cgtttcggct tggtcattga gattatgacc tattgctatt ttattggctt
    10741 taatcttatc cttaatttca taaaacattt catatcttag cttccttgct ccttcttcta
    10801 atgataatcc ctcattttca caatattttg gtacattaat agactttaca aagaatataa
    10861 ttcccatatc ctcacaaagt ttagatacat ataatgcatc tttttgagct tctatccctc
    10921 ttatttgatg gtttaaatgt gctgcatata tttctatatt aaaatctttt tttaatctat
    10981 ttagtacatg caataaacaa actgaatcag gtcctccaga aagacctaaa actattttat
    11041 cgcctttttg tattaaatta tgtttattta tagtacttag taccttatca aatatcatat
    11101 ttatccctct tacacttagt tttattcact tttaagtata ctttctataa aaaaacgcta
    11161 aacccttgta tcaattttaa gaaattaaag tttaatataa atataataat accaaataaa
    11221 ttaaataaaa ggtagttttt tcactacctt tataaaattt ctggaaaata gccatagtta
    11281 ttatttagta cctatgtata tatctatttt attcctacct aaaaataaat cttgtacctt
    11341 tatattatag tctattttca attttatgtg ttccccttct tgtatattta tatctaattc
    11401 tcttgtatca atatcaatta ataaagtacc ttgtggggtc acatactttg tagtactact
    11461 ttctccacat ttaaacagca ttgttgagtt aatagcacca aactttttga tactaacttg
    11521 atttttaagt atctttatag tattagttat ttctatattt tcttcttttt ccttgtaaat
    11581 aacatatatt ccatcatttt tataaaaaat tttaccaaag gcagtcatct ctatggtgtc
    11641 catatttcct ttttcatcat attgtctagt atttatactt atttttacac tcaacgattt
    11701 ttcctccata gattcttcat ataaactagt atttttgtat ttctactttt tgaatcttat
    11761 caattttttt ctttaagaac tctcttgcta tatctgaaaa tttttcaggt atatctgata
    11821 cataatattg ataagttcca tgaatttctg tattgtttat aatattttgc acctctaaaa
    11881 tcttttttaa atcctttgca gtctctttag ctggattaac aagttttata tgctctccaa
    11941 cttcttcacc tattgttctc tttaaaatag gataatgagt acatcctaac actaaagaat
    12001 ctatattttt ttctttcaat tcttgtaaat atatctttgc tgtcaattta gccacttctg
    12061 tatttgccca tccttcttca acaataggta caaataaagg acatgcttta ttaacaattt
    12121 ctatactctc atctatttta gatatttcca agttgtatgc ttttgaactt atagttcctt
    12181 cagttcctat tattcctaca attttgtttt ttgtagaact tacagctgtt ctagctcctg
    12241 cttctataac tccaattatc ggtatatcat atttttcttg agcttctttt aagcttcttg
    12301 cagtagcagt gttacatgct ataactatag cttttacacc ttttgttttt aaaaagttta
    12361 tagcttgaaa agtatattta attatagttt ctttggatct tgaaccatat ggtattctgg
    12421 cagtatctcc aaagtatatt atatcctcat ttggtaatat cttcattatc tcttttagaa
    12481 ctgttaatcc acctaatccc gaatcaaaaa ctcctattgg tttattgttc atctttatac
    12541 aacacctact ttacattttt gtgtttaaca acaacttatt tatcgctaaa atttatattt
    12601 atattcataa ttaatatatt attacctaaa tgattattat agtttatttt acacaaaaaa
    12661 taaaggagct atcttaaatt agaaaataat ttctacaaaa agacaactcc tttcactact
    12721 taaaaattta aatttatttt gcaaacacat gatttcctat tctcatataa ggattcaatc
    12781 tatttatcca tttgcaagtg gctatttctg gattccaaaa atatactgct ttattagttg
    12841 ggtcagttcc ataaagagct tcctgagctg ctttacgtgc tgagtctgtt ggtgccatct
    12901 ttattgaacc atcaagcaca actgagaaag catttttttg atatatgact tcttctattg
    12961 tgtctggaaa tctagggtcc aatactctat ttattactac agctgctaca gcaacctgtc
    13021 cctcatagct ttctcctcta gcttctcctg caaccaactt agataataac atcaagtcat
    13081 tatcagataa atttattact tctttctttg ctatattttt ttcttgtttg tttactttct
    13141 taatattttc tgttggttca tatgcaaata cctctttaat aggcataaat ataaaagtca
    13201 aagctaatag tgtagccatc agtttactcc acctgtccat gattaaaacc actccttaca
    13261 ttcttatttt taaaattttt tctctaaatc cttgactact tcaagtactt taaacttaat
    13321 ttttactcta cttgtttttt ttggtgtatc ttgttttatt aacttatatt ctttatcagt
    13381 taaaacttcc ttcaacttat catctgtaga tttatctatc actccattag attcatcaac
    13441 aaaacatagt ggagggaaca taacacacca ccagtttttt ccttcacctt tcccaatgat
    13501 aatctttaat gctttatatt caccagctgg aagaactata ttagaatatt gtttagtagg
    13561 gaaattgcta tattgtatac ctacctttac actgtaatta tatccatttt taagaataat
    13621 atttttactt atttcttcca gactactata ttcctttttt ataatagctt cactttcttt
    13681 tatacttttt gaattttgaa gctttggctg taaatatttt attacttcat ctctaacttt
    13741 tagtttaagt tcttggtctt catctgtatt gctgtttgct ataacatgaa atcttattaa
    13801 tttatcttta taatcttttg atatattgtc tacttttttt acctcaccat ttattactat
    13861 tgtcattatt gatatgactg atataagact taatattaat agtcccaatc taatcttaat
    13921 ttttctcatt gaaaattccc cctcaagata aatttatatc atcaattatg tccaattaaa
    13981 tttaatttat tcataatatt ttttaatact aataaaaaaa gctatcttaa aatgattaca
    14041 atcattttaa aatagctttt taaaccttat attttataag tctttactaa tcatagcctt
    14101 atctatcata aactgctctg ctttttctat atgctctgta gcatacttct tggatagctc
    14161 actatcacct ttaattatag catcaagtaa atatttatgc tcttcaacaa tattatgtga
    14221 tgtatcataa gcagacatat aggtaactct aaatctatat acttgttccc acaatgagtt
    14281 tattaattgg attaattttt tattattagt tgctttaaat atacattcat gaaattctac
    14341 atcaagtttt aataacgcat ctacatcgga ttccaaagtg ctttttttaa attcttctga
    14401 tatatcttta agctttttaa tatcttcatc actaattctt tcagcggcaa gatatgctgc
    14461 taagccttct aggcttgctc ttacttctaa tacatccata atatccttta atgacatatt
    14521 tgccacatac gcaccttttc taggcaacat aacgactaaa ccttctaatt caagctttct
    14581 tattgcctct ctcactggag tcctacttac tcctaattgt tctgctagtt gcacttccat
    14641 tagcctttga ccaggcttta attttccttc taagattgct tctcttaaat tctcaaagac
    14701 tacatctctt aatggcttgt aattatccaa gttcagttta gttaaattct ccacaaattt
    14761 caaccccttt ttgactgcta ttaacaacat acacctgttt atattttttt aataattctt
    14821 tttttccaat tagagcatct tctttatttt taaatagtcc aaaaactgta ggaccacttc
    14881 cactcatcat agaacctaaa gcattatttt tcatcattac ttgttttata tcacttattt
    14941 ctttgtgttt acctatagta acattttcaa gaatatttac catgctttct gatacagctt
    15001 ttatatcttc agattttaaa cactctatca aatatttatt atttggtctt tttttaatat
    15061 tattcaaatc taatccttga taaacttctt tagtagaaac gaataagtct ggtttgcata
    15121 tcaatatatt tgtatcacat ggtaaacctt tgatgtttgt tagcttttct ccaatacctt
    15181 gagctaaggc aggtcttcct gatatacaaa aaggaacatc tgcgcccaaa ttaagtccta
    15241 tctcttttaa ttcatcttca gataatctaa gttcccatag gtgatttaaa cctactaata
    15301 ctgcggctgc attagaactt cctccagcca tccctgctgc tacaggaata tttttttcta
    15361 tgaatatttc tacacctttt tttatataaa atttattttt aagtattttg gcagctttat
    15421 aaacaatatt atcttcatct aaaggaatat ctaaactagt gctttttacc tttatttcat
    15481 cttcgtctaa ttcttttatc tttactatat cgtataaatc tatcgtttgc attatcattt
    15541 caacaaaatg ataaccgtct tgcctttttc ccaagacatc aatggataaa tttatttttg
    15601 ctctactctt tagtcttata aaatccattc tatcctcctt gtttaaagaa taatgcatca
    15661 ctaacaataa tattatacta caaaaaataa aataataggg tattataata ccctattata
    15721 cttaattact ttaaattttt taatattaat ctactaatac gacttttttt tctaaaataa
    15781 gacacttacc aggcttaatt ggttcatcaa gttttatatc attaagttct gcaatttcat
    15841 tttctgttgt attgtatttt tttgctatat tccagaaagt atctccttct ttgcatatat
    15901 atacgattat gctaggagct ttagataaat catatacacc ttggtcttct cccttgataa
    15961 taaaattttc tgctttctta tctaatgctt cagtaaatct cttaattttg ataatcaggt
    16021 ctatctggtc cctattcaaa tcaacttcga ctttatcaat acatgctgta ttaaacacag
    16081 atgctgtatc agttagatta tccatttcta tatcatgttc aaatggaatt tcctcactaa
    16141 ttttataaac caattttaaa ccttcaactg ggacaaataa aatttcaact tttatgattc
    16201 cttgtataat gcttttattt ccttcaatat aactattttc tatagacatg gttggacaaa
    16261 cgcttacaat atcttttatt tgtatatcat cattatcatt tcttatgcct tctctaacca
    16321 taaatgtttc ttcactacgt cttaaagtct tatttaattg aataggtttg tggtcaaatt
    16381 ttattatctt ttgaggcgaa tatgcatctt gtaatacttc tcttgtaact tcatctgtaa
    16441 cttttacctt acaacaagcc atacaatcta tttctaaaag acctgtgttg ctttcactat
    16501 tttgtttgaa aatatgatta aaatctgaca tagacaacaa tacttcttca gtcataccat
    16561 cactaactcc agggacttct acaaattgag taaactcaat acctactcta tccaactcta
    16621 caagttcacc ctcatatgta caagctaacg gatttatttc taatactcca ccaataataa
    16681 ctttattgtc agtcactcta ctttctttta ctttaacaca tggatttaaa cttattatag
    16741 attgaatttc ctctgtgttt attgttatag tatctcttat agaactttct gctttttcta
    16801 ttccaactat atcttgaaaa caaatttcct ttctgtgctt ttgtatgcct tccacttgcg
    16861 ccacatcttt tacaatgtct aacctttgct tttcaaacaa acttcccctt atattcataa
    16921 gagctcctac tttaatcttt ctctcattca ttatagtaca atccatatgc tctacttctg
    16981 aaaataacat gtattccata tcttgaataa cattgtcttt ttctattact tcgtttatat
    17041 ctacttttcc gtctacatta gaaatagtat ttttatcatc tgcaatatag attacattat
    17101 aattaaaact acctctgcaa agtatcttcc catctgccat ttcaattttt ttaagtgata
    17161 tgtatccttc tgtttttaca atttcatata catctaattt tttgtctggt acaactgcct
    17221 ccgcttcaat gaatgtttga aattttccaa agtctattct attgtcaact ttaattacat
    17281 ctttaattaa ttccatagtc tacctcctta agtattataa aaatatcaca ctatatttat
    17341 atttaaggag caaaaaaaaa attacaccta tttttaaata ggtataattt taacttattt
    17401 gtaatttatc ttgatctcta aaaacttgca actttacatt agatgttaat aaatctgagt
    17461 aactataaga tactctagga tatccattac tttcatcatc taactttata acaaacacgc
    17521 ttggataaac tttttctagt ataccctctt ttgtaataat ctgctttctt cctttattag
    17581 ctttcaacaa tattttcttt cctatatgtc tctctaagct tactcttatc ttatctagag
    17641 tttgaacagt agccacaata tcaccttctt taacgtttat atgtttacat aatatcacat
    17701 ataaacattt ttgtcaaatg tttaaactaa ttattttata tattttttgc aaaaatgtca
    17761 atactatttt tgaagatata cagtataatt atgttaattt ttgctaatgt aatattgttt
    17821 ttggcattgc ccatctaaat tttcctcttg tttcagaacc accaattccc ttaacacctg
    17881 taatagtctg ctctataacc tcatcaatag gaactactac atcaattctt gaacaagcaa
    17941 ttttctccac tataaaaaca gggtctaatg catgtatcat tattcttcca ggcgaacttg
    18001 catagtttgc tcctgcactt attatttttt cataatttga ttggcatgct cctgcgaata
    18061 tgacaagatt atccaaattt ggttgccatt tacgtgcttc ttttactgtt ttaacaaaat
    18121 ttgaagagtt tctatagtta ctcatatctt ctatatctcc tctttttatt gtcattgcat
    18181 catgacctgt tattactagt atatccggat tatatttttc tagtagtgct cttacttctt
    18241 tatactgatt ttgctctgaa acagctacac ctactgcagg tattccaagt tgagcatata
    18301 catccaagca aatttttaaa tattctttat ctccatctat ctgtagtact tttccaggca
    18361 ttccatatgt gttaggattt aattgaagtt ttggaactgc tctagtcatt cttttttgtc
    18421 tttctttagc ttttcttact gacttatata ataaattttc tacattttta tctattaata
    18481 tatcttttat atcaggtgct tttactaatt ctaggtcatc aatataagca tctgctatta
    18541 ctctaaatgc aattcccttt agtatagcta ttttctcatt attttcatct acaccaaaag
    18601 agactatttt aaatactata tctttgttat gtgactttct agctacaatg tctcctacct
    18661 tcatagttaa acctccaata aatttttatc ttagtttata ctatgttcga tataaaactt
    18721 tgtttcctaa tgtcaaaaaa acatttctta taatacttct tttatcactc ttaaagcatt
    18781 tttatagtat atcttttcta tatcatcttc actaaaccct tcttttttta gaggttcata
    18841 cagtttaccc atctgagata tatcttcaat ctcaactttt gaatctattc catcaaaatc
    18901 tgaccctaga gatacaacat ctattcctcc aacatttaca atatgtttta tgtgtctaac
    18961 catatcttca agtttacttt cacttttatc acttaaaaat aagtggaaga agtttatacc
    19021 tgtaactcca cctttatttg ctaatacttt aatcatatca tcagttaaat ttctagaatg
    19081 attcatcatt gctcttgaat tagaatgtgt agcaattatt ggtttagaag aaatctttgc
    19141 aatttcataa aatccaccat ctgaaatatg agaaacatca accaacattc ccaattcatt
    19201 catcttatgt accacttctc ttccaaaatc agtaagccct ttttctctat attctacttt
    19261 attatgagga aagctcaatt cattcacatg attccaactt attgtcatca ttctaacccc
    19321 taagtcgtaa aatttcttta aattttctaa tttaccttca agtactgcac cttcctcaat
    19381 agataaaaga gctgtaagtt taccttctga ttggtttttc ataatttctt catagttagt
    19441 agctaaaact atttcatcac tatttttttt catttcctca tgaaatttat ttgccatact
    19501 catgcaataa tcaaaaggat gttttacttc ttcagtatca acaaaaagag caaatgtttg
    19561 agctaatgaa tccccctttt tcaatctgtc tatatcaaca gaatatttat tagacttaag
    19621 ttcacttgtt tctacatttt ccattaattt tgctatagta tcacaatgta aatcaataaa
    19681 tttcatattt ataccccctg tatattttat atttatatct aaaaatagaa atagttgtcc
    19741 ttatagacaa ctattgacaa ctatttttta atattctttt taacattact taatcttatt
    19801 cttcttttaa gttaggtatt acttttttaa cttcttcaat ttgatgccat gttttatcta
    19861 tattattttc actaatatat ttttttaaat cagttaaaga tgtaaaatct ttaactgata
    19921 aattgtcatc atcatctgca aatcttaaaa taaacatgag actcccttac tttccacaac
    19981 atttcttata tttttttccg cttccacatg ggcatgaatc atttcttcct atttttgctt
    20041 ctttaactat tgttttagac ttcttataag cctttattat ttcttttctt tggtctgctg
    20101 gtagtatatc ttcccaacct tgtaaattat atagccaatg agcctcaaca gttaccatat
    20161 tgttatataa tttttcccaa tctattttta tagaaacttc tttatcagct tctacttctt
    20221 ctaaaactat atcttctttt aagctttcac ttattccatc tatgaatccc atgaaaaatt
    20281 cattagtagt tccaaatttt tcagccaatt cacttacttt accttcaaca acatccattt
    20341 tattatttaa tatttcattg tatattccag cttcaacttt caaatattct tcccagaatt
    20401 ttacttctgc ttcttgactt tcatgattat cacttaaatt tctccattca gtatataaac
    20461 tcatactttt tcctcctaag tatacctata tttttatagt ttttatagta taaaatcttt
    20521 tagttagatt ggaagtttct tctttttgat tataccatat tctatttaaa gttaactctt
    20581 atattatatc ataattaaac aattctttta atacttttat agcatactct tggtttataa
    20641 aataagggct tgtcgcaatt gttattactt tggctttttt aattaagttt tttatcttgt
    20701 aaaatttgag ttcaaatggt atatagtcca tatcacttga aaatatatcc aaatctatat
    20761 caagaacaaa ctctgattct acttctaaat caaatccata tagactatct attattatta
    20821 attctgaaaa tatgttatat tttaaagcag gttttataaa acttcccaca tttaaaactt
    20881 catttgtata tctaaataca tcttttagat tatttacatc tacatcatag ttctcaggtt
    20941 ctctagtatc cttatgttgg tctacatgca ctaacttgca tccttttgta aactcaccct
    21001 ttaacaaaga ttttgcccaa aaataaaatg catggttatg attgtcaaac acatatatct
    21061 ttttatttcc caggacatat tcgaccatat tctccaatcc ttttgctttt atttccttat
    21121 tttcatctac ttcattaaat actacctcat tgcctaacct tacatcattt aatgtaccat
    21181 ttattagttt tggaacgtat atgctcttat tttctctttt atcatatgaa aatacattat
    21241 ttcctactgg tttttctata taaaatccac tatattcata attttccata aaactttatt
    21301 tcctccattg ttatataaat atataagtta taattttaaa aattaaaatg cacttattgt
    21361 aaatcatatc atctattata gaaaacatct tatataacta aatataatat cttctctcaa
    21421 tatgtattat acaataagtg caaaatatat ttatataaaa tatactacat tcctataaca
    21481 aaaccatcag cttcaattgg aaggtaacta actcttctat tcaactccac ctttccaaaa
    21541 aatactaccc aatatggtct aaaaatactt tcaattttaa ctatttcaat ctctgggatt
    21601 cctcccataa acctatgagt taatctcata gccattttat ttgcctttgc ttttactctt
    21661 cgttcgtcct tatcactata ctgcacaata ttacaatcca cattttttac aacttcatat
    21721 gtaggaaaat cttgtactat actaccagaa cctgtagaac cattcactaa aatttttaat
    21781 tcatttatat cattagaata tctcctattc ttgaaaatgg atttcgtttt gtgaatttta
    21841 agtgtgataa ttttaaactc tatataatga agtctaactt catgagcata tttgttcttt
    21901 aatattagct tactaaataa agaatttttt ccacttttag ctatctctat agcttcttct
    21961 tttgtaattc ttataggtaa cgctcttata tccataaaat cattctcttt cttatttttt
    22021 tcttgtcatt tttaaaactc tatatatata atcaaaaaat attacaatta caactgccat
    22081 aactccatat ggaattattt ttccaactat aatatcattt ctagtcaata taccataaaa
    22141 tataaatcct gttattaaaa agtacaataa tactagaaaa ccgtctattc caagccattt
    22201 tatttctaaa tcttttttta ccttagacac taatttagac atagcagttt ctccttttat
    22261 agattatttt gtgtatttaa attttcacct attctattac caatcatcca tgcaataaat
    22321 gaaaaaggta tagctatcac aagaggctct aactcaaagc tctgaactgg aaatatttta
    22381 aaataaccaa aagtcactcc accaacaatc attcctaaaa taccacccat agatgttctt
    22441 cttccatttc caagaagccc acctactata ggtacaaatg ccgaacccat ccaaatactt
    22501 cctacaaata tacatgcatc atatacattt tcaaatctaa atgctacgct aagccccata
    22561 actgctgcta aacatacacc tattctagta aactttacta attgtttctg agataactct
    22621 ttttttgtaa ttcttccata tatatcattt gctaatgtag ccccagctgc tagataatag
    22681 ctatccaatg ttgatattat agaacctaaa attcctatta taaatattac tcttattcct
    22741 tgtggtaatg tatctaaaac taaagttata tatccagcag ctggagccat ttctggataa
    22801 gtagctctta ctataagtcc tgtcatagtt aacaccatgt caaaacatat ccatagtgaa
    22861 aaacaggtta ataaggctct tcttccaacc ttaggagaat ctgctgctga aaatctttga
    22921 taaaaagttg ggtctgaata agctccaaaa gaatatacaa ttaacatcaa tgctttcata
    22981 gctgacatac cctttgtagg gtgcataagc tgtggtgcat ctttgagtgc ttctgtaaga
    23041 ccttgaaacc ctcctatttg ttcaaattga cctggcataa ccatagttaa accaaatacc
    23101 atacaaaaaa acaataccat atctgtaatg gcaactccca taagcccacc aagtactgta
    23161 agtacaacga ctactcctac cattattaat cctattaatt ctttatctat tttccatgct
    23221 acgttaccta tagttcccat agcagttatt tctccaagtt gtgcacaata tataaacatc
    23281 aaaattgccc caattatagc aacatgcttg ccataaaaac tttccagtaa atcaggaact
    23341 gttatattgg ttcttatatg aatccttgga ccaacccaca atgctaaagg cattctccca
    23401 atatgtgcag ctattgacca aactgcccat gcagatattc catatatagc cgcatactct
    23461 acactaccta ctgtaccaac tcctccatac catgatgcaa ccaaagttcc tactattaag
    23521 gaccatggta aacttcgatt tcctaggtaa taactttcca tatcttttac atttctagaa
    23581 aaataataac ctattcctaa taatataaat gcaaatataa ctataatccc attttcccaa
    23641 aatgttaaca tatctaatct ccacattctt atattttaat ttttaacttt aatatctaaa
    23701 tatgaacaac tctacccatt tccataaaaa taggtagagt tatataataa ttataagtat
    23761 ttaagtaatc ttgttattaa gcaattttat tgtttaaacc tttattttct cttttattta
    23821 ttttatttaa agcataagta gcaaatatcc ctataactgc acatactaca gataaaataa
    23881 atatatatgt atatcctgtt tgtccatatt tatctaacca attacctgca atagtgtaat
    23941 aaaacgcatc tggagaaaat cctataaatg aagcaaatcc aactactgct cctgtagttt
    24001 ctaaagatat attagactct gaaacagatg caaagtatat acctctaaat ccaaataaaa
    24061 ttacacttag tattatcatg tttattacag ctatccatat aaatcctgta ctcttaggaa
    24121 taaccaagta agcagctgta cttactgtca ttaatataaa tcctacaaac attactctta
    24181 tagatgaacc aactttatct gttataacac cagcaactgg agatgctccc atttttataa
    24241 cataagttct tattattgat aaagcagaaa ctagagtcat tggcattaca taaacttctg
    24301 ataagtatgg acttaaataa gttaaacttg agaatactaa ataagttgaa aatattataa
    24361 gaccaattaa ccaagccttt ggcattgtaa ctacttttaa caatgactta atacttaatc
    24421 cttcatctga tgctccacta tcttttttct cttctactaa gaaaaataga agtataccac
    24481 atattataga tgctgcagaa tataaccata ctacatattt gaatcctact gttatttcag
    24541 caaatttacc aaagaaataa agacctataa aagaaattaa tgtacctgat acacctgata
    24601 acccttcata aaaaccaaat attcttcctt gctctgactc acttccttgc attctaacaa
    24661 ccttaacaga ggctgagaag aaggttaata ttgtcgtaaa tccccataat acaaatatta
    24721 aaagtatcat actatatgat gggaatgtag agaaataaaa tccaagtatt cctgaagcaa
    24781 ttaaagaaaa agttattaat tttctaactg agaatctatc tgcaaaccat cctcctataa
    24841 aataagatac cattcctact aatccatata aactcaataa gttccctatt tgtgtatgac
    24901 ttaatgctaa agcttgttgc attgggtcat aaaatgatga tttcatatat ggtaaactat
    24961 acatagctgt tgttccaaat gccaatatga atattatcaa aaatctttta acattatttt
    25021 tgctttccat tgattctctc tccttaaaat tttattgttt ataatctcat tcatgtaatt
    25081 ttattttaat ttttttattg cttgtttaaa gtcatttatt atatcatttg aagattctaa
    25141 tcctacagct attcttatta gattttcccc attcatttga actaatgtat gctcttcccc
    25201 taagcttgtt gctattgttg caagctctaa agaattcatt aatcttctac tagcttggtc
    25261 tcttgtcaat ccattgatac catccttaag tttaaatgaa actacacctc cacctaaacc
    25321 attcatttga gttttacaaa gctcatattg aggatgtgat tttaatgctg gatactttac
    25381 caattccaca ttctcttctt cctctaaaaa ttctgctact gctaatccat tttcacaatg
    25441 ctttttcatc ctcatatcta acgttttcat accccttaaa atcatccatg cactcattgg
    25501 tggtaaagat gctcctgtaa aacaacataa acttggccat ctaactaaat ctattaattc
    25561 ttttgaacct gctactgctc cccctaaagt atctccatgt ccatttataa acttagtaag
    25621 actatgtatt actaaatctg cacctaaatc tattggtctt tgtacaattg gtgtcccaaa
    25681 agtactatca actatagcta agcttttatt ttcatgagca atttctgcta ttgtttttat
    25741 atctactaag tctaatgatg gatttaaagg actttctata taaactattt tagtatttgg
    25801 tctcattgct tcttttacat tttgtggatt tactgcatct acaaatgtaa cttcaactcc
    25861 aaatttagat aacaactcag acatgaataa tttagtgtgt gaaaatattc catctgaact
    25921 aactatatgg tcaccacttt ttaccaatgc taatatagta gatgttattg cccccatccc
    25981 tgatgtacta gatatggcac tttctgcatt ttcaagcata gccaacttag cttctaactc
    26041 tgtaagagta ggattacact ctcttgtata cacatatccc catgtcatac acaactcttc
    26101 aaaatgctct actgtctttg cagcaaatgt tgctgtttga catattggtg tagccaatgc
    26161 acctgttgtt gggtctgcac tatgtcccca atgtattatt tttgtctcta aatcttgatt
    26221 aatattgtta ctcattttga tttcctccca ttttgactta tttatacaac gttttcccta
    26281 ccaaatttca tcaatttagc ttagtcttaa tacatttttt caagtatact tttttatttg
    26341 ttataatttc taaaaatatg acacttattt tgttttttta cagttctaat tataaactct
    26401 atagtaacta tagagtcaat atgtttttga tatttttttt acaatgttta aaatagtcag
    26461 tacaaaaata ggtatatctt agaataacta aagtcatcct aagatatacc tatttttata
    26521 tcacaatata aataattaca tataagcatt agttttttta tcataaatag atttttcaag
    26581 atttatcatc ttttcataaa tatattatag ttaaatattt taatattacc taacatctac
    26641 aataaaatat actcttaaaa taaaattata taattaaaaa tactctataa aagctaaaaa
    26701 gtttttctat tcgctacatc taaaaataat tagatagagg tataaatgta tttagtttat
    26761 ttatacctct agtcttttat aaattatatc tctactaaat tgatttttta gcacgaataa
    26821 gtgtgctctt ggagatacca gtcatcttca caacctctct atatggctta gaatttaata
    26881 accccaatgc atattgtatc tgttgattgc tgtatttctt tggcctacca tctttaaagt
    26941 cctttttctt tttagcaaat tcttttccta attgagtacg ttctattatc atatttctct
    27001 caagttctgc aactgcaagt aatgtagtca aaaagaattt acccattgaa gtattttcta
    27061 aaaggcctat atttaaaata tgaacactta cttctttagc aaataaacct tctattagtt
    27121 gtattccttc tgatgtactt ctagctagtc tatccagctt agttgcaaca agtaagtctc
    27181 ccttttttag agatgatata attttttcaa atttaggcct gtttgtagta gtgcctgtat
    27241 aagtttcctt tattatttta gcatcattat atttattcaa aatttcttgc tgttgctgat
    27301 acaaactgtt gttgtctgtt tgattttttg tacttacacg gcaatatcca tatataataa
    27361 tcatcacttc ctaacataaa gattttgtac agaagttacc cagaagcttg tttttactta
    27421 tctttatcca ttttactaaa acgatttttt ggtgtcaata ct
//
LOCUS       DAEORM030000049        27288 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.049, whole genome shotgun sequence.
ACCESSION   DAEORM030000049 DAEORM030000000
VERSION     DAEORM030000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 27288)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27288)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 27288)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27288
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.049"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            complement(136..315)
                     /locus_tag="KRH23_002769"
     CDS             complement(136..315)
                     /locus_tag="KRH23_002769"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226047.1"
                     /translation="MGNLKRQCDVSSGREKADIVLKNGTIINVFTEELITGDVAIVGD
                     TIVGIGDYKGNVEID"
     gene            complement(621..1775)
                     /locus_tag="KRH23_002770"
     CDS             complement(621..1775)
                     /locus_tag="KRH23_002770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative manganese transporter"
                     /protein_id="HHS5226048.1"
                     /translation="MEMLISASEEAFLHVGSMIGFFILLFGYINYKTSGNFTNIISKN
                     RKFQPLIGALIGAIPGCGGSLAIMPLYINGKLSFGAIIASLIASMGDAAFVLISSNIK
                     MYFFVTIVSTITGIITGQLVDYFKLEEKLGLKNRRKSDKYDISKNNPKENKEQHNHDE
                     IILDTLAKSHGNTNRLAFIITHGKGYKIYIGIIVIGFIFMSLAHSGLNLPIIEKLHSL
                     EEVIAVIGILFSIIYMWCFKKVFKNSNQKEEENKKISLREMLIHSVGEISFVITWIFI
                     AYLIYDLIILILGGDEYLVKLVLSTGVISVFIGAGLGLIPGCGIQIVLMSFYLKGTIP
                     LGAVIANSISQDGDALFPLLAMDKKSSLWAMIITTIPAILVGMIVYAFLG"
     gene            complement(2020..2859)
                     /locus_tag="KRH23_002771"
     CDS             complement(2020..2859)
                     /locus_tag="KRH23_002771"
                     /EC_number="1.17.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-3-methylbut-2-enyl diphosphate
                     reductase"
                     /protein_id="HHS5226049.1"
                     /translation="MNIKIAKNAGFCFGVKRAMKMAWDEVEKNDSGIYALGPLIHNKQ
                     AVAKYEEKGLKTVNEIDTIPNHENMIIRSHGVPENIYKEAKDKKLKIVDTTCPFVKKI
                     HTVVSEYHNKGYEIIVIGDMKHPEVIGINGWCENSAIIIKTLEQMENMEFDNSKKYCL
                     VAQTTINPELYISIVNKLSDKLEEIVFNDTICSATKTRQESAKELAKEVDCMIVIGGK
                     HSSNTQKLVKVCEDLVPTFAIETKDELDVNTLKKYKNLGITAGASTPNWIIEEVVTFL
                     ENL"
     gene            complement(2872..3468)
                     /locus_tag="KRH23_002772"
     CDS             complement(2872..3468)
                     /locus_tag="KRH23_002772"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lysophospholipid acyltransferase family protein"
                     /protein_id="HHS5226050.1"
                     /translation="MNFYRFVINIFKGFSKIFFKYEVIGAENIPDRGNIVIASNHKSN
                     LDPIFLAAAIENREIAAIAKKELFKVKPLGFILKKLHVMPINREKPDVSTIKTILRSV
                     RDGYVLGIFPEGTRIKGDSFGKAKAGLSVFTIKSKSKVVPVSIISKYKLFSKVIVYIG
                     EPISFEEHFKEKLSNDDHERISQEILEVIKQNYFKYSK"
     gene            complement(3519..4169)
                     /gene="cmk"
                     /locus_tag="KRH23_002773"
     CDS             complement(3519..4169)
                     /gene="cmk"
                     /locus_tag="KRH23_002773"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004127 - (d)CMP kinase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HHS5226051.1"
                     /translation="MGNLVIAVDGPAGAGKSTIAKIVAKKLNINYIDTGAMYRAVTYK
                     CLKSGIDVNNEKEVIQIAENSDIDFKDNNIYLDKEVINEEIRTIEVSNNVSNVAKIKE
                     VRQLMVEVQRKIGMKSSVILDGRDIGSYVFPDADYKFFLVATPEERGNRRYKELCNKG
                     YNTTLEEVIEDIIRRDEIDSNREFAPLVKSNDALEIDTTGKTIEEVVEEVVSKINL"
     gene            complement(4215..5468)
                     /locus_tag="KRH23_002774"
     CDS             complement(4215..5468)
                     /locus_tag="KRH23_002774"
                     /EC_number="1.14.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HHS5226052.1"
                     /translation="MSKVIVVGGGASGMMAALSASKNNNEVILVERNGELGRKLRATG
                     GGRCNFTNNREIEDFFDKVVSNKKFLYSSFYTFTNKDLISYFESRNLEYKIEEENDHK
                     VYTKNDKSIEVIEVLNKDLLNHNVKIMYNKKVIDIITEEIALKDDSNKDKSKYLIKGI
                     ILDNGDKILGDKVIISTGGVSYSKTGSDGSMYKILKKHGHTLNKLYPALVPLTIEEKW
                     IKDLQGISMKNVEISCKIKKRKISKSGDMLFAHFGITGPCVLIMSSYINKIIEKEKVE
                     LNIDFLPNLSTDEISSIIRAFPNKNVLNNLKQILPQNFLKEIFSLLSLVDKKASDLSK
                     ADEIRIIEYIKNMKLTCNGTTGINTGMVTSGGISVKEINSSTMESKLVKNLFFTGEVI
                     DIDAETGGYNLQIAFSTGYLAGISV"
     gene            complement(5492..6133)
                     /locus_tag="KRH23_002775"
     CDS             complement(5492..6133)
                     /locus_tag="KRH23_002775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HHS5226053.1"
                     /translation="MGNTFYIVRHGQTDWNILGKTQGHGNSDLTPQGIEQAKELSEDI
                     GKYSIDYIFSSDLGRAMQTAQILGDKLNIEVQKTEALREMGFGVWEGLLIKEIQKDYS
                     DIYATWRNEPHLVNIPEGETLKIIKERVDAFIKELNEKYDNKNIILVTHSITLRVMLL
                     SFLESGMENIYRIKQDNTALNIVEFKDYGPVIVKMNDTSHIKNHVKINNSALE"
     gene            complement(6335..6748)
                     /locus_tag="KRH23_002776"
     CDS             complement(6335..6748)
                     /locus_tag="KRH23_002776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1653 domain-containing protein"
                     /protein_id="HHS5226054.1"
                     /translation="MLELKNNLGISERKLKYPCIYKHFKGKYYATMGLSKAIDDIENI
                     CEIYGKENLIQNRNKYKLVIRHTEREEDIYVYRDLDGNFYHKKEEDTNDLVLYKTLYD
                     DTGIFARPLDMFLEKVDTDKYVNSIQEYRFEEVYK"
     gene            complement(6899..7240)
                     /locus_tag="KRH23_002777"
     CDS             complement(6899..7240)
                     /locus_tag="KRH23_002777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family DNA-binding domain-containing
                     protein"
                     /protein_id="HHS5226055.1"
                     /translation="MKEENFINVEYEDKRFSINSKEVLYIEKQEYEVKIYTESGNYEV
                     GENAPCIRKLLKEENFFKCSNSYIVNLDKCEFYLSNNCIFVNNNFIRILGSERKKKLK
                     KKLEKLYDYED"
     gene            complement(7534..8193)
                     /locus_tag="KRH23_002778"
     CDS             complement(7534..8193)
                     /locus_tag="KRH23_002778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HHS5226056.1"
                     /translation="MLDAFITIVSSIIEIWSCKKVFDYTSQSKTDLKKLNMYFFFSVF
                     LIISSLYINIGANSRILICIFVMFVFYKSNYKVNIYKCLVISFFYWLILIGINGLSML
                     LVATVSNLDNMNVLLSGSLYRYEAIFLGKLMLGILLYVYKASFKNFKISKKEIYICIP
                     MIANLLSFFVLYDYIINLVKISPERRTAFLVIVLLLILSNISIFVLIHIILKIKIRKI
                     R"
     gene            complement(8724..9101)
                     /locus_tag="KRH23_002779"
     CDS             complement(8724..9101)
                     /locus_tag="KRH23_002779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HHS5226057.1"
                     /translation="MTISKIPQAELKVMKFIWEKNDTVTSKETIEAMERKYGWKQTTT
                     LTLLSRLVKKHFLSAEKIDRYTHYTIVVGHKEYLSVETKDFLSNIHDNSLQSLISALH
                     DDEVVDKDMLDLFESHFKNLEEE"
     gene            complement(9288..10259)
                     /locus_tag="KRH23_002780"
     CDS             complement(9288..10259)
                     /locus_tag="KRH23_002780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HHS5226058.1"
                     /translation="MLLRASIGMGIVIFTMAFVQNVYQLLGLRILQGVFTGYATACTT
                     LIATQTDKNHSGWALGTLATASTTGSLIGPTVGGYIESILGLKSTFIITGGLLFVSFI
                     ISILFVVDNFKPKEIKESISIPKEQLNILPNKFLIASIFVTTFITQLALYSIEPIVTI
                     YISQLTNFASNVALIAGLTFSASGLANLLAAQKLGKMSDKIGPQKVLLISLLWAGIIF
                     IPQAFVKTAWQLMLLRFLLGLSVAGLNPSVNSLLKKIAPEEYVGKIFGYNASAQYIGC
                     SSGAFLGGQISAHLGIRTVFFSTSLLLFMNALWMYKFTGLFIKDKTK"
     gene            complement(10293..10490)
                     /locus_tag="KRH23_002781"
     CDS             complement(10293..10490)
                     /locus_tag="KRH23_002781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug transporter"
                     /protein_id="HHS5226059.1"
                     /translation="MELWKRNLFVCWIGMFFSSIGMSQIAPILPLYIKQLGVTDVSLI
                     QQYSGIIFGCTFVVAAFFSPI"
     gene            complement(10558..11769)
                     /locus_tag="KRH23_002782"
     CDS             complement(10558..11769)
                     /locus_tag="KRH23_002782"
                     /EC_number="4.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase family protein"
                     /protein_id="HHS5226060.1"
                     /translation="MYSNEDYKFIEENAPCYIYDETNIIEKCKELKNNILGFDFLYSI
                     KTNPYNKIVKSIAEQGFGADASSTNEVMISSECGVSKDDIYYSSPGKTEIDIETVLDK
                     CIIIADSITEIELINKISKKHNQKVKIGIRINPDFTMDDDSAKSSKFSIDIEDMSSVF
                     KMLSMCDYVSVVGIHIHIKSQVLDFEKLGHYYEKCFFIALNLNKSKYINIEFINFGSG
                     LGVAYDNLRENPLNLKELSKLTQKIAFTNSNTLKSRLLIESGRFIVCKSGNYYVKIVD
                     IKVSRGKKYLIVKNGLNGFMRPIISNLIENITCGVELEGQEPLYTSNHAFSLSVLNNL
                     KEEEYVNVVGNLCTSLDVIANNVKLKKANIGDLISISNAGSYSYSLSPLLFSSYEFPK
                     QYYKRKDGYIE"
     gene            12050..12652
                     /locus_tag="KRH23_002783"
     CDS             12050..12652
                     /locus_tag="KRH23_002783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HHS5226061.1"
                     /translation="MEVCILMGSPKKKGNTAAILKPFIEELENYNSNIEVIWLYDCKI
                     EPCIACKKCQDNLFDFGCYCKDDVQKIFKKILMCDLIVFATPIYSWYCTSPMKALLDR
                     LVYGMNKYYGNEKGPALWAGKPVALITTCGYRPEKGADIWENGMKRYCKHSQLKYIGM
                     LVERDLGKPNFMNKEKEEHSRQFAKQIYYILDSSIEVDNC"
     gene            complement(12908..13879)
                     /locus_tag="KRH23_002784"
     CDS             complement(12908..13879)
                     /locus_tag="KRH23_002784"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate kinase family protein"
                     /protein_id="HHS5226062.1"
                     /translation="MKKVISIGEALIDFIPNQNGGKLKNVSEFRRVAGGAPANVSAVV
                     AKLGGKSSFISKLGKDAFGDYIIDVLNEVNVNTDYVLRTSKANTGLAFVSLKEDGNRD
                     FSFYRNPSADMLLEADEVKKEWFNNCHILHFCSVDLIDSPMKLAHKKAIEYALESNSI
                     ISFDPNIRLPLWDSEQSCKKAISEFLPFAHIVKISDEELEFITGENDIEKSLHKLFVG
                     NVELVLYTKGKDGVDAYTKKVKGMCKGVKVNAIDTTGAGDSYIGSFLYTLLYKQITLN
                     DIKEMKQETLNEYLEFSNYYAARSTTIKGAISSYATKEEITEFIKNL"
     gene            complement(13905..15386)
                     /locus_tag="KRH23_002785"
     CDS             complement(13905..15386)
                     /locus_tag="KRH23_002785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HHS5226063.1"
                     /translation="MYKEPKYRTILESTKEELNKLRNISLNDKYKPLFHIHPQHGLLN
                     DPNGLAYYNGKYHVFYQWYPYDATHGMKHWAYVSSDDFVNWNREDVALIPIESYESHG
                     AYSGNAIEVDGKLHMYYTGNIKYSAEDRYAYQNLAIMNKDGKITKYENNPIVSEIPKG
                     YTGHVRDPKVFKIKDKYFMLLGAQTSDKKGVIIVYESKNSIDWNFKGELNVKNIDEDF
                     GYMWECPDYINIDEKDILIFSPQGVEPKGFDYQNIYNVVYAIGNMDLDNLTFEIDTMK
                     ELEKGFDFYAPQTFIKDSQIILFAWAGMGEVLYPTDKNKWAHCLTVPRKLNIKNNKLL
                     QMPVDELIKLRYDETSGQNTIKNNINIIENDENVYELNINIKNIDSNKFGLELFSSQD
                     EGVKLEFNKLGNIVTLDRSNFKKVFGVEYGTNRKEYINIDENTNIKVLADRSILEIFI
                     NEGEVVFTSRIFAKENSNQIRVYSDKIVEYEYTKFKLKQGIEL"
     gene            complement(15405..15482)
                     /locus_tag="KRH23_002786"
     CDS             complement(15405..15482)
                     /locus_tag="KRH23_002786"
                     /inference="COORDINATES: protein motif:HMM:NF012587.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIB"
                     /protein_id="HHS5226064.1"
                     /translation="MKGVAHCVTRLRIVLDSNNKANIKL"
     gene            complement(15723..16709)
                     /locus_tag="KRH23_002787"
     CDS             complement(15723..16709)
                     /locus_tag="KRH23_002787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HHS5226065.1"
                     /translation="MKKITINDIANLAGVSKSTVSRYLNNKDISDSTKEKIKTIIDEY
                     GYEPNAFAQSLRAKKTYFIGIITPCLDSFVKSKIMMAIDEELKELKYTSLIINTNRKI
                     RSEIDSISKLASLKVDGIILIGTEITKEHKNEIEKLDIPIVVVGQKVDGINSIVNDDY
                     GAGYKMGQYIANKGYKNIVYLGVDESDISVGLNRKKGVLNGLKDKGYDAKVFYTDFDQ
                     ETSIQRSGEMLESENPDIIICATDNIAIATMKEINKRGKSIPQDISVAGFGGYDVLSI
                     ISPKLTTIKFENKNAGKVAANTIVNLIQERKEPLLKEIKFELIEGESTINKN"
     gene            complement(17093..18847)
                     /locus_tag="KRH23_002788"
     CDS             complement(17093..18847)
                     /locus_tag="KRH23_002788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp23"
                     /protein_id="HHS5226066.1"
                     /translation="MYIMNKKFKKFSKNLSILILVLTMFLFNNLTANAQIKEDSIIGI
                     DRYETAGLIADRQTYDTVILVNGDKNLSDGLSSSGLAGAINAPILLTKKSEIPKATLN
                     RLDNKSLNVVKKVYIIGGYNTIENSVEKDIKRKGIQVERINGNNRIETSYNVAKKINE
                     VSSVKEVMLTNGFVGEADAMSIAPVVAKNKGAIILTDGKSVPFKTEGLNVYAIGGKSA
                     INEDLVNETKATRIGGNDRFETNKKVMEKFYNGATDFYITNGYQLVDALTLSPLAKEK
                     PIVLVADGSNKGILKGAKSITKVGGIDANIYKQCLDMIKYNNMDMTPNILKHLTSVEG
                     NEVSEILIESDNLGVVVEKTNTNKFEFDYVSVTNEKNCTFSVYKENSSNNIKNGKLVV
                     SAKKKIDKKDSDLQDMNGDNMINANKDRMVNVIKIGVPDKMYSNFKVDVESGSVELYN
                     IKGGATVDVNDGIANIVDNNVTNPFNINTNSGISGVTAETISSEIKFRANNGIVNVTA
                     TNINGNISLFGSDNKGTFDGIFKLNLKKEPSNLHLKLIGNGINKLPEGWSKDYILGNG
                     QPIIEVKNNGINNISIGE"
     gene            complement(19065..19955)
                     /locus_tag="KRH23_002789"
     CDS             complement(19065..19955)
                     /locus_tag="KRH23_002789"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HHS5226067.1"
                     /translation="MAKLTLEHIKGNTYYIPLPTIVGVYVDGKDAILIDSGNNKDTAR
                     QILRLLEEHNLSPKLIINTHSNADHIGGNAYLKNQTKCKIATTKIEGYFTENTILESA
                     FLYGGYPSKALKNKFLLAKESEVDYIIPSNGKIVDTELEAISLPGHYFETIGVRTPDN
                     VLFVADSLTPENIITKYHFFFLLDIDSQFKTLEKLRMLEADFFVPSHSVKTTDIKSLI
                     NINKEKMEEIIDNIKKVCYEPVMIDEVIEKMCDLYNVKLDANQYVLVGSTIRSYITYL
                     YENNMVEYIFDGGKMMIKAV"
     gene            20104..20964
                     /locus_tag="KRH23_002790"
     CDS             20104..20964
                     /locus_tag="KRH23_002790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HHS5226068.1"
                     /translation="MLLKKDRITFSEILILIVGCILMAISLNLFFNPHAIAAGGITGL
                     GVVLNSLFGVELWIVNLLLNVPLFIFAYKILSKKDCFKTVLGIIFLTIALKLTANMAT
                     LDITNDMYLAIISGSILMGVGQGLIFRINGSTGGTDLMALLLNKYFPTFSIPVLMGIV
                     DCVVVVLSGIVNRQVEIALYSTVALYILVKVSDLLIEGFNYSKSFTIISDLSKDISKK
                     IMEDLDRGATILKGEGAYTGENKNVLLVVVEKKEVVELKKLVKNVDPNAFIIITDIHE
                     ALGNGFKKIE"
     gene            21420..21986
                     /locus_tag="KRH23_002791"
     CDS             21420..21986
                     /locus_tag="KRH23_002791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006950 - response to stress [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HHS5226069.1"
                     /translation="MSVSLQKGQRVSLVKDNNPVKNLVVGLGWDMNKLGKKNYDLDAF
                     AIALTNQDKMNVRGDLVYFGNLKHPSKAIIHTGDNLTGKGEGDDEQIIVNLEDIPEYV
                     HKIVFGVSIYKAKKRDQDFGQMNNSFIRLIDSNSKQELFKYNLQEDFSGKVTVLAGEI
                     YRRNEEWKFNALGIGQNEELRELINTYK"
     gene            22026..22607
                     /locus_tag="KRH23_002792"
     CDS             22026..22607
                     /locus_tag="KRH23_002792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006950 - response to stress [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HHS5226070.1"
                     /translation="MGITLAKGQKVSLTKSNPGLKKVIVGLGWDINKYDGGFDFDLDA
                     SAFLTGTDGKVTNDGDFIFYNNLKHASGAVEYMGDNRTGVGDGDDEQINVDLSKIPQN
                     IAKISFSVTINEAITRRQNFGQVENSYIRIYNEETNEELIKYELGEDFSIETAIVVAE
                     LYRHNGEWKFNALGSGFEDGLAGLCKNFGVNIG"
     gene            complement(22664..23581)
                     /locus_tag="KRH23_002793"
     CDS             complement(22664..23581)
                     /locus_tag="KRH23_002793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR substrate-binding domain-containing
                     protein"
                     /protein_id="HHS5226071.1"
                     /translation="MTIRSLEIFVKVAECGKMSEVARNMYITQSSVSQAISEIEKEYG
                     VKLFDRISKKLYLTEAGKKLLGYGRHLLAVNEEMNDCMKHCAKNIRIRVGATVTVGTC
                     VISPIMLELYKVNPLIEPEVFVEDTRLIAKKLLNSELDIAIVEGKIKHPDIVTKSIIN
                     DNLVLICSHKHEFYKRDSIEVSELSNQPLIMRELGSGTRAQLEKQLKELKIPMNIRWS
                     CYNSEAILRAVVDNFGIAVISELLIEDYLKKHLLWACDIEGINLHRTFDIAYHRSKFF
                     TENISAFFDISVEYGKKQARKKSRSVNSL"
     gene            23711..25342
                     /locus_tag="KRH23_002794"
     CDS             23711..25342
                     /locus_tag="KRH23_002794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HHS5226072.1"
                     /translation="MKVLIIGGVAAGTKTAAKIKREMGDNCSVTILNKGDDISYAGCG
                     LPYYVGKIIEDKSSLIVNTPESFSKLTGAEVRCGVEVTSIDRNAKQVILKTLSTGEKE
                     NLSYDKLVIATGADPIKPPIPGIDLPGVFFMRTPNDAIKLRDSIENGIKRAVVIGGGF
                     IGLEIAENLSAMGIRVSVVDMAEHVMPGFDTDFAEYVENHMADKGIMIFTGDQVVGIE
                     GENKVEKLRTKNRAIKTDLVVMSVGIRPNTGFLKDTGLEFAPNNTIIADEYMLTNDKD
                     IYVVGDCAFVKNSLTNKPTWSPMGSSANHEGRICAQNISGKSKTYNGVLGTTVVKLPE
                     LNAGKTGLSKEIAEKEGYNVCSVTIATDDKAHYYPGASNFIIRMVAEKNTRKLLGVQV
                     MGPGAVDKIVDIAATAITLGADLYSLESMDLAYAPPFSTAIHPFVVAVNVLQNKLNGE
                     LDSVLLDEIEDFDSWTKLDVSKAPSIPSLRYIPVGEINGEIEGLAKDEKILLICAKGK
                     NSYMAQNRLRRFGYTNTKVLEGGILFYPNLKVMEE"
     gene            25345..26292
                     /locus_tag="KRH23_002795"
     CDS             25345..26292
                     /locus_tag="KRH23_002795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HHS5226073.1"
                     /translation="MSNVTAEQKKEVKGRGFLPSRDGEHFAARIITVNGVINASQAKK
                     IAEAAEKFGNGQLAFTTRLTVELPGVKFEDIEALSEFIASENLITGGTGSRVRPVVAC
                     KGTVCVHGLADTQALAAEIHEEFYKNWYDVKLPHKFKIGVGGCPNNCIKPDLNDLGIV
                     GQRVPDYDSELCVGCKKCAVVEVCPVKAAKLTDKGKLEIDSNLCNNCGKCIESCNFDS
                     IEEKESGYKVYIGGKWGKSVRPGTQIDRLFSKEELMTLIEKAILLFREQGNTGERFGI
                     TIDRIGADKFIEMLLSDEVLERKEEILEALLHLTGGAVC"
     gene            complement(26577..26840)
                     /locus_tag="KRH23_002796"
     CDS             complement(26577..26840)
                     /locus_tag="KRH23_002796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1883 domain-containing protein"
                     /protein_id="HHS5226074.1"
                     /translation="MEYSYSKMNLKKGDIVEVNLEKQANVILLDHINYVKFKNQKNYD
                     YYGGFAKKNPCRMKVPNTGTWYLVVNQDGNSGIVNFSINTIQN"
     gene            complement(26939..27184)
                     /locus_tag="KRH23_002797"
     CDS             complement(26939..27184)
                     /locus_tag="KRH23_002797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226075.1"
                     /translation="MFIDEELEGYILTCKISEDFKNIPEYSDEEFYVTVYKDESSDSG
                     YYALLENKEERVVWDGEVVANNIFNNLWIVVNKVKTG"
BASE COUNT         9203 a         4250 c         3100 g        10735 t
ORIGIN      
        1 ttagctttag gggtttccag caattcaagt agtattggat aggttctatc ctatctctac
       61 atataggttt ccctatatgc tgactatttt agctactaac tcatgactaa agtcacgagt
      121 gtgcgtagct attttttaat caatttctac attgcccttg taatcgccaa ttccaacaat
      181 agtgtctcct actattgcta catctcctgt tattaactct tctgtaaata catttatgat
      241 tgtcccattt tttagtacaa tgtcagcttt ttctcttcca cttgaaacat cacactgtct
      301 ttttaaatta cccattttta caactcctcc taagtttttt atatcaatat actgactgta
      361 ttacgtatta tagtttaatt tattaatata tattatatat gagttttgat agaaagtatc
      421 acttgaaatt tgttccataa ttcctttaat taaatagaga gaacatgagg aataatatta
      481 tctcccatgt tctcattaat atttaagcaa taatttaatt catattgaat tttttatttt
      541 tatatttaat cttcactatt cttataaata aatttatgtg ctttattatt tttttaatac
      601 ttctttattc ataattatat ttaacctaaa aatgcataaa ctatcatacc tacaagtatt
      661 gctggtatag tagtaataat catagcccat aaagaagatt ttttatccat tgctaaaagt
      721 gggaaaagtg catctccatc ttgagaaata gagttggcta tcactgcacc aagtggtata
      781 gttcccttca aataaaatga cataagcaca atttgtatcc cacaacctgg aataagtcca
      841 agacctgcac ctataaatac acttattaca cctgttgata atactaattt aactaagtat
      901 tcatctccac ctaaaattaa tattatcaaa tcgtaaataa gatatgcaat aaaaatccat
      961 gtaattacaa atgatatttc tccaacagaa tggataagca tttctcgcaa agaaatcttt
     1021 ttattttctt cctctttttg attagaattt ttaaatacct ttttaaaaca ccacatataa
     1081 attattgaaa ataatattcc aatcactgct attacctctt ccaatgaatg taacttctca
     1141 attataggaa gattaagtcc agagtgagca agtgacataa atataaaacc gattactata
     1201 attcctatat aaattttata tccctttcca tgtgttatta taaatgcaag tctatttgta
     1261 tttccatgag atttagctag agtgtctaaa attatttcat catgattatg ttgttcttta
     1321 ttttctttag ggttattttt acttatatca tatttatctg attttctacg gttttttaac
     1381 cctaattttt cttctagttt aaagtaatcc actaattgtc cagttattat tcctgtaatt
     1441 gtactaacta tagtgacaaa aaaatacatt ttaatatttg atgaaataag tacaaatgct
     1501 gcatctccca tactagctat taaacttgca attattgctc caaagcttaa ttttccattt
     1561 atatacaatg gcattattgc caaacttccg ccacaacctg gtatggctcc aattaaagca
     1621 cctattaagg gttggaattt tctgtttttt gatatgatat tagtaaaatt tccactagtt
     1681 ttataattaa tatatccaaa taacaaaata aaaaatccaa tcatagaacc tacatgtaaa
     1741 aacgcctctt cagaagcgga tatcaacatt tccattaatt tacctcctag actaattttg
     1801 caacaattat attatattct attttctatt gataatcaat atcaatattt cttttgaatt
     1861 tctaatatta aaaagtgcgc atcttatact cttagttttt catcttaaga tacacacttt
     1921 ttgatattag gttatctatt taccacatgt aatatgaaat caaaggtgga tattatgata
     1981 aattataaca atgtccacct atttttatta cctatcaaat tataaatttt caaggaatgt
     2041 tacaacttct tctattatcc aattaggtgt agatgcccct gctgtaatac ccaaattttt
     2101 atatttttta agcgtattta catccaattc atctttagtc tctattgcaa aagttggtac
     2161 taagtcttca caaaccttta ctaacttttg agtatttgaa ctgtgtttac ctcctataac
     2221 tatcatacaa tcaacttctt tagctaactc tttagctgat tcttgtcttg tttttgtagc
     2281 tgaacaaatt gtatcattaa atactatttc ttctaattta tctgatagtt tattaactat
     2341 acttatatac aactctggat ttattgtagt ctgtgcaaca agacaatatt ttttggagtt
     2401 atcaaattcc atattttcca tttgttctaa ggtctttatt attatagctg aattttcaca
     2461 ccatccattt atacctataa cttctggatg cttcatatct ccaataacta ttatttcata
     2521 gcctttatta tgatactcac ttactactgt atgtattttc tttacaaatg gacatgtagt
     2581 atccacaatt tttaattttt tatctttggc ttccttatat atattttcag gaactccatg
     2641 agaccttatt atcatatttt catgatttgg tattgtatca atttcattca cagtcttaag
     2701 acctttttct tcatattttg ctactgcttg cttgttatga ataagaggac ctaaagcata
     2761 tatgccagaa tcattttttt caacttcatc ccatgccatt ttcattgctc tttttactcc
     2821 aaaacaaaag ccagcatttt ttgctatttt tatgttcata actttacccc cttattttga
     2881 atatttaaag taattttgtt ttatcacttc taaaatctct tgtgatatcc tttcatggtc
     2941 atcattactc aatttttcct taaaatgttc ttcaaatgat attggttctc caatatatac
     3001 aattacttta ctaaaaagtt tatatttaga tattattgat actggaacaa ctttagattt
     3061 actttttatt gtaaatacag aaagacctgc cttagcctta ccaaaagaat ctccttttat
     3121 tctagtaccc tctggaaata ttcctaatac ataaccatct ctaactgacc ttaaaatagt
     3181 ttttattgta gatacatctg gtttttctct atttataggc ataacatgca atttttttaa
     3241 tataaatccc aatggtttta ctttaaacaa ttctttcttt gcaattgcag ctatttctct
     3301 attttctatg gcagcagcca agaatatagg gtcaagattc gatttatgat ttgatgctat
     3361 tactatattt cctctatctg gaatattctc tgcacctata acttcatatt taaaaaatat
     3421 tttagaaaaa cccttaaaaa tatttattac aaatctataa aaattcacgt ttatctccct
     3481 tcaacactac atttattttc attatgatgc ataaaaaact aaagatttat tttagataca
     3541 acttcttcta caacttcttc tatagttttt cctgtagtat ctatttctag tgcatcatta
     3601 gattttacca atggtgcaaa ttctctattt gaatcaattt catctcgtct tattatatcc
     3661 tcaattactt cttctaaagt agtattatat cctttattac aaagttcttt atagcgtcta
     3721 tttcctcttt cttctggagt agctactaaa aagaatttgt aatctgcatc tgggaaaaca
     3781 tatgaaccta tatctctacc atctagtatt actgaacttt tcattcctat ttttcgttga
     3841 acttcaacca tcaactgtct tacttctttt atttttgcta cattagaaac attattgctt
     3901 acttctattg ttcttatttc ttcatttata acttctttgt ccaaatatat attgttatct
     3961 ttaaaatcta tatccgaatt ttcagctatt tgaataactt ctttttcatt attgacatca
     4021 ataccacttt ttaaacactt ataagtaact gctctgtaca tagcacctgt atctatataa
     4081 tttatattta gcttttttgc tactatcttg gctattgtac tttttccagc tcctgctgga
     4141 ccatctacag ctataactaa attacccata tatacacctc tatttattca tatttaatta
     4201 ttaaaaaatt atatttatac acttataccc gcaagatatc cagttgaaaa tgctatttgt
     4261 aaattatatc caccagtttc tgcatctata tcaattactt cacctgtaaa aaataagttc
     4321 ttaactaatt tagattccat agtagaagaa ttaatttctt taactgaaat accaccagaa
     4381 gtaaccatac cagtgtttat acctgtagtc ccattacaag ttagcttcat attttttata
     4441 tactcaataa ttctaatttc atctgcctta gacaaatcac ttgccttttt atcaactaaa
     4501 gataatagag aaaaaatctc ttttaagaaa ttttgaggta gtatttgctt aagattattt
     4561 agaacatttt tatttggaaa tgctctgatt atactagaga tttcatcagt acttaaattt
     4621 ggtaagaaat ctatatttaa ttctaccttt tccttttcaa taatcttgtt aatataagaa
     4681 gacattataa gaacacaagg tcctgttatc ccaaaatggg caaatagcat gtctccagat
     4741 tttgatattt tccttttctt aatcttacaa gatatttcca cattcttcat ggatattcct
     4801 tgtaaatctt taatccattt ttcctctatt gtaagtggaa ctaaagcagg atatagtttg
     4861 tttaatgtat gtccatgctt tttaagaatc ttatacattg aaccatctga acccgtcttt
     4921 gaataactca ctcccccagt tgatataata accttgtctc ctagtatttt atctccatta
     4981 tctaaaataa tcccttttat tagatacttt gacttgtcct tattagaatc atcttttaga
     5041 gcaatttctt cagttataat atctataact ttcttattat acattatctt tacattgtga
     5101 ttgagtaaat ctttatttaa tacttctatt acttctatag atttatcatt tttagtgtat
     5161 actttgtggt cattttcttc ttcaatctta tattccaaat ttctactttc aaaatacgaa
     5221 ataaggtctt tatttgtaaa tgtataaaaa ctactataga gaaatttttt attactgaca
     5281 actttatcaa aaaaatcttc tatctctcta ttattggtaa aattgcatct accgccacca
     5341 gttgccctaa gttttcttcc taattctcca tttctctcaa ctaatattac ttcattattg
     5401 ttttttgaag ctgacaaagc tgccatcatt ccagaagctc ctccaccaac tactataact
     5461 ttactcataa atttctcctt ataattgatt cctactccag tgcagaatta tttatcttta
     5521 catgattttt tatatgactt gtatcattca tttttactat aacaggccca taatctttaa
     5581 attctactat atttaaagca gtattatctt gcttaattct atatatattt tccatacctg
     5641 attctaaaaa tgacaacaac ataaccctca atgtaattga atgtgtaaca agaattatat
     5701 ttttattatc gtatttttca tttagttcct ttataaaagc atctactctt tcctttataa
     5761 tcttaagagt ttcgccttct ggtatattta ctaagtgtgg ttcatttctc catgttgcat
     5821 atatatctga ataatctttt tgaatttctt ttattaaaag gccttcccaa actccgaatc
     5881 ccatttctct aagtgcctca gttttttgaa cttcaatatt gagcttatct cctaaaattt
     5941 gagctgtttg cattgctctc ccaaggtcgc tactaaaaat ataatcaatt gaatacttgc
     6001 caatatcttc agaaagttct tttgcctgtt ctataccttg aggcgtaagg tcagaattac
     6061 catgaccttg tgtttttccc aatatattcc aatccgtttg tccatgtctt actatataaa
     6121 aagtatttcc catatgtcct cctaatatat gcctattttt tattaaatat aaattatcac
     6181 ttctcaaaac ttaattatat catataatac tttactttgt ttctatttta taatctaatc
     6241 taacatatta tttacaataa atctcatttg tatttctgca aattattgta ctgttaaaga
     6301 atttttctaa atttataaac atatttctct tatattattt atatacttct tcaaatctgt
     6361 attcttgaat tgaattgaca tacttatctg tatctacttt ttctaaaaac atatccaaag
     6421 gtcttgcaaa tattcctgta tcatcatata aggtcttgta taaaactaaa tcattagtat
     6481 cttcttcttt tttatgataa aagtttccat ctaaatccct ataaacatag atatcttctt
     6541 ctctttcagt atgtctaata actaatttat atttatttcg gttttggatt aaattttctt
     6601 taccatatat ttcacatatg ttttctatat catcaatagc cttgctaaga cccattgtag
     6661 cataatattt ccctttgaaa tgtttataga tacaaggata ttttaacttt ctttcactga
     6721 tacctaagtt attctttaat tcaagcattt tattataatc tcccatatct cgtccctttc
     6781 ttttaaaaag tattttattc tgaaataagt tacttgtttt atattttatc ataatttaaa
     6841 atttattaat aatacaatca ataaataaag aggctgtata aaatacagcc tcccaatatt
     6901 aatcttcata atcatataat ttttctaatt tcttttttaa tttctttttt ctttctgaac
     6961 ctaaaattct tataaaatta ttattcacaa aaatacaatt attgctgaga taaaattcac
     7021 acttgtctag atttacaata taactattac tgcatttgaa aaaattttct tctttcaata
     7081 gttttcttat acaaggagca ttttctccaa cttcataatt accactttca gtataaatct
     7141 ttacttcata ctcttgcttt tctatgtaca aaacttcttt actattaatt gaaaaacgtt
     7201 tatcctcgta ttcaacatta ataaaatttt cctctttcat ttccatccct ccaagtactt
     7261 ttattaattt aattttagtg ttttttatca atataatcta tcggaaatat atgtaagact
     7321 gatttactta agatatttaa ataattatta ttaatattaa tgtataagtt tattttttaa
     7381 cattaatttt taaagttaaa aagacttttt ttaatcatat ccgtatatat aagtatatct
     7441 atctttaata aaataacttt tatagaaatt catgtaaaat tatacataaa aaagtaatta
     7501 ttaactttta atttaaatga atcgtgttaa aatttatctt attttcctaa ttttaatctt
     7561 aagtattata tgtattaata caaagattga aatgttagat aatattaata gtaaaactat
     7621 tactaaaaaa gcagttcttc tttcaggaga gatttttaca agattaataa tataatcata
     7681 aagtacaaaa aatgacaata aatttgctat cataggaata catatgtata tctctttttt
     7741 acttatttta aaatttttaa aagaagcctt ataaacataa agtaatatac ctaacattag
     7801 ctttcccaag aatattgctt catatctata taaactgcca ctaagtaaaa cattcatatt
     7861 atccaaattg cttactgttg ctactaataa catacttaat ccatttatac ctattaatat
     7921 taaccaataa aaaaatgaga ttaccagaca tttatatata ttaaccttat agttagactt
     7981 atagaaaacg aacattacaa atatacatat caatattcta ctattagctc ctatatttat
     8041 atataaagaa gaaataatga gaaaaacaga aaagaagaaa tacatattta gtttttttaa
     8101 gtcggtcttt gactgactag tataatcaaa aactttttta catgaccata tttctataat
     8161 agaagaaaca attgttataa atgcatctaa cataataata tcctcaaaaa tgattaaatt
     8221 atatttttta taaaatatat cataaaaaat acatactaat tatagcataa aaaacacact
     8281 taaatttaat ataattattt aatattttta acaactttct atagtacatt ttaaaatatt
     8341 tacagataag ttaccaataa taaagtttaa aaatataaaa atcatttctt acttttagtt
     8401 tacctataat aacaaaagac aggtttatat tgtaataatt aaaaatagta aaatatattt
     8461 tgatatggtt aaatagaaat aatactttag attaatgaat attgacaagt tataaaatta
     8521 ttttaaattt taaaaatcat ttcttattta aataagtggt atcatttaac ttgatactcc
     8581 ctattccaat tattttaggc attttactaa ttagagaacc tatttaatat tactttatga
     8641 atagtgagta gctgattaaa taataccatt tatggttttc agccatagat taattaaatt
     8701 cttagagttc tatcctgata taattactct tcttctaaat ttttaaaatg actttcaaat
     8761 aaatccaaca tatctttatc aacaacttca tcatcatgta gtgctgaaat taaactctgt
     8821 aaagaattgt cgtgtatatt gcttaaaaaa tcttttgtct caacacttaa atactcctta
     8881 tgtccaacaa ctattgtata atgagtgtat ctatctattt tttctgcact taaaaaatgt
     8941 tttttaacaa gtcttgataa aagtgtcaat gtagttgttt gtttccaacc atattttcgt
     9001 tccatagctt caatagtttc ttttgatgtt actgtatcat ttttttccca aataaacttc
     9061 ataactttta attctgcttg tggtattttt gaaattgtca taaccttacg cccctctcaa
     9121 acttttatta aattaatact atcgcaatat agtttttaag tcaaagattt tgtcgataat
     9181 aatattttcc aatttttacc atagggttat tttttatata attctatgat aaattacata
     9241 aaaaatattt attttacatc ataaaattag aaatgtaaat agtatgatta tttagtctta
     9301 tctttaataa acaatccagt aaatttatac atccaaagtg cattcataaa caacaataaa
     9361 cttgttgaaa aaaatactgt tctaatacct aaatgtgctg atatttgtcc ccctaaaaat
     9421 gctcctgatg aacagcctat atactgggca gatgcattat atccaaatat ttttcccaca
     9481 tattcttctg gtgcaatttt tttaagcaag ctgttaacag aaggattaag ccctgcaact
     9541 gacaacccta ataaaaatct caacaacatc agttgccatg cagtttttac aaaagcttgt
     9601 ggtataaata taatcccagc ccataaaagt gaaattaaca atactttttg aggacctatt
     9661 ttatccgaca tttttccaag tttttgagct gctaataaat ttgctaatcc tgatgcagaa
     9721 aatgtcaatc cagctattaa agctacattt gatgcaaaat ttgtaagttg tgatatatat
     9781 atggttacaa ttggttctat agagtataaa gctagttgag taatgaatgt ggttacaaaa
     9841 atagatgcaa ttaaaaattt atttggcaat atatttaatt gttctttagg tatagaaatt
     9901 gattctttta tttctttagg tttaaaatta tctactacaa ataaaataga gatgataaat
     9961 gatacaaaca acaatcctcc tgttataata aatgtacttt taagacctaa gattgattct
    10021 atatatcctc ctactgttgg accaattaat gagccagtag ttgatgcagt tgcaagagta
    10081 cccaaagccc atcctgaatg atttttatct gtctgtgttg caataagagt agtacatgca
    10141 gtagcataac ccgtaaaaac tccttgaagt attcttaatc ctaataactg ataaacattt
    10201 tgaacaaacg ccatggtaaa tataactatt cccatcccaa tacttgcacg taaaagcatt
    10261 gattttcttc catatttatc agcagctttc cctcaaattg gcgaaaagaa tgctgctact
    10321 acaaaggtac atccaaaaat tatacctgaa tactgttgta ttaaactaac atcagttacc
    10381 cccaactgtt taatatataa tggaagtata ggtgctattt ggctcatccc tatagaacta
    10441 aaaaacatac ctatccaaca tacaaataaa tttcttttcc acaattccat atagaattac
    10501 accccctgca ttttaaattt tttcaataat actaagttta ttaatttatg ctattgttta
    10561 ctcaatatat ccatcttttc ttttataata ttgtttagga aattcataac ttgaaaataa
    10621 tagcggtgat aaagaatagg agtaacttcc agcattacta attgaaatca aatctcctat
    10681 gtttgctttt ttcaatttaa cattatttgc aattacatct aatgatgtac agagattccc
    10741 aacaacattt acatactctt cttcttttaa attatttaat actgaaagag aaaaggcatg
    10801 atttgatgta tataatggct cttgaccttc taattctact ccacaagtaa tattttcaat
    10861 taaattagaa ataataggtc tcataaatcc attaagtcca ttttttacaa taagatattt
    10921 tttccctctt gatactttaa tatctacaat tttaacataa taattacctg atttacaaac
    10981 tatgaaacgt cctgattcaa taagaagtct tgattttagt gtgtttgaat tagtaaaagc
    11041 aatcttttga gttaattttg aaagctcttt aagattaagt ggattttctc taagattatc
    11101 ataagctact ccaagtccac taccaaaatt tataaattca atattaatat acttactttt
    11161 atttaaattt aaagctataa aaaaacattt ttcataataa tgtcctaact tttcaaaatc
    11221 caatacctga gatttaatat gtatatgaat cccaactaca gatacataat cacacatact
    11281 taacatctta aaaacactgc tcatatcttc tatatctata ctaaatttgc ttgatttagc
    11341 actatcatca tccatagtaa aatcaggatt tattcttatt cctattttaa ctttctgatt
    11401 atgcttttta gatatcttat ttataagttc tatttctgta atactatctg caataattat
    11461 gcatttatct aaaacagttt ctatatcaat ctctgttttg cctggtgatg aataataaat
    11521 atcatcttta gaaactccac attctgatga aatcataact tcattagttg aagaagcatc
    11581 tgctccaaaa ccttgctctg caatgctttt tacaattttg ttatatggat ttgtttttat
    11641 agaatataaa aaatcaaaac ctaaaatatt atttttcaat tccttacatt tttcaattat
    11701 attagtctca tcatatatat aacatggtgc attttcttct ataaatttat agtcttcatt
    11761 tgagtacata ttttttacct ccaagatttt aaatataatc ataaattaag caattataat
    11821 cctataagat aattttacaa taaattacca tagttaacta cacacatata tgtaaaaaca
    11881 tacctaaaat atttttaatt atagatacat tccaactttt attgctaaaa caatttgttt
    11941 caattttatt acaaatatac aaagtgtatt gttgttaacg tattctcata gtatcctaaa
    12001 actatattaa gcactaaaaa ctattttaaa atactgtgga ggtatcaata tggaagtatg
    12061 cattcttatg ggaagtccta agaaaaaagg taatactgct gctattttaa aaccttttat
    12121 tgaggaatta gaaaattata attcaaatat tgaagtaata tggttatatg attgtaaaat
    12181 agagccatgt attgcttgta aaaaatgtca ggataactta tttgattttg gatgttattg
    12241 taaagatgat gttcagaaaa ttttcaagaa aattcttatg tgtgatttaa ttgtttttgc
    12301 tactccaatt tattcttggt actgcacttc tccaatgaaa gcgctacttg acagattggt
    12361 gtatggaatg aataaatact atggtaatga gaaaggcccc gctctatggg caggaaaacc
    12421 agtagcactt attacaacat gtggatatag acctgaaaag ggtgctgata tttgggaaaa
    12481 tggtatgaag cgctactgta agcattcaca gttaaaatat ataggaatgc ttgttgaacg
    12541 tgatttaggt aaacctaatt ttatgaataa agaaaaagaa gaacattctc gtcaatttgc
    12601 aaaacaaatt tattatattt tagatagttc aattgaagta gataactgct aaagacataa
    12661 tactccaagt aaagtattga taatataaat aaatcttaca taatttgctt atttaaaata
    12721 agatatatat tcttctaaaa agtaacaata attaaaatat tttttatcat ttcaacaatg
    12781 ataaagaggc ttatctctat tttgagacag cctctttatt gctttttata tgttaattat
    12841 tttcatagta aacatcctta aaaactcttt acatgttact tccttcaaaa cctattactc
    12901 attcctacta taaatttttt ataaattcag ttatttcttc ctttgttgca tatgaactta
    12961 tcgcaccttt aatagttgta ctacgagctg cataataatt agaaaattct aaatactcat
    13021 ttaacgtttc ttgtttcatt tcttttatat cattcaatgt tatttgttta tacaataagg
    13081 tgtataaaaa tgaacctata taagaatctc ctgctccggt tgtatctatt gcatttactt
    13141 taaccccttt acacatacct tttacttttt tagtgtatgc atctactcca tcttttcctt
    13201 ttgtatataa tactagttca acattcccca caaagagttt atgtaatgat ttttctatat
    13261 cattttctcc tgttataaat tctaattctt catcagatat cttaacaata tgagcaaaag
    13321 gtaaaaattc tgatattgcc tttttacaag attgctcact atcccataaa ggtaatctta
    13381 tattagggtc aaagcttatt atactattac tttcaagtgc gtattctatt gcttttttat
    13441 gtgctaattt cattggacta tctattaaat ctactgaaca aaaatgtagg atatgacaat
    13501 tattaaacca ctctttttta acttcatcag cttctaaaag catatctgca cttggatttc
    13561 tataaaatga gaaatcacga ttaccatctt cttttaatga tacaaaagca agtcctgtat
    13621 ttgctttact tgttctcaat acataatcag tatttacatt tacttcattt aatacatcta
    13681 ttatataatc accaaatgca tcttttccta acttagatat aaaactcgat tttcctccaa
    13741 gctttgctac aacagcacta acatttgctg gagctcctcc tgctactctt ctaaattctg
    13801 atacattttt taatttacca ccattttgat taggtataaa gtctattaaa gcttctccta
    13861 tactaattac ttttttcatc ttttctaccc cttataatgt gtttttataa ttcaatacct
    13921 tgctttaatt taaatttagt atactcatac tctactattt tatcactata aacccttatt
    13981 tgattagaat tttctttagc aaatattcta ctagtaaata ctacttctcc ttcatttata
    14041 aaaatttcta aaatacttct atccgctagt actttgatat tagtattttc atcaatattt
    14101 atatattctt ttctatttgt tccatattca acaccgaaaa cttttttaaa gttgcttctg
    14161 tctaaagtta caatgtttcc taatttgtta aattctaatt ttacaccttc atcttgtgat
    14221 gaaaataatt ccagcccaaa tttattgctg tcaatatttt ttatattaat attaagctca
    14281 tatacatttt catcattttc tataatatta atattattct ttatagtatt ttgcccactt
    14341 gtttcatcat atcttaattt aattaattca tctactggca tttgcaatag cttattattt
    14401 tttatattta attttcttgg aacagttaga caatgtgccc atttgttttt atctgtaggg
    14461 tataaaactt ctcccattcc agcccatgca aatagtatta tttgtgagtc ctttataaat
    14521 gtttgtggag catagaaatc aaatcctttt tccagttctt tcattgtatc tatttcaaat
    14581 gttaaattat ctaaatccat attaccaata gcatatacta cattatatat attttgataa
    14641 tcaaatcctt taggttctac tccttgtggt gaaaatatta atatatcttt ttcatctata
    14701 ttaatataat ctggacattc ccacatgtaa ccaaaatctt catctatgtt ttttacattt
    14761 aattctcctt taaaattcca atctatagag tttttagatt catatactat tataactcct
    14821 tttttatcac ttgtttgtgc tccaagtaac ataaagtatt tatcctttat tttaaatact
    14881 tttgggtctc ttacatgtcc tgtatatcct tttggtatct cacttactat tggattattt
    14941 tcatatttag ttattttacc atccttgttc attatagcta agttttgata tgcatatcta
    15001 tcttctgcac tatattttat attccctgta taatacatat gcaattttcc atctacctct
    15061 atcgcattac ctgaatatgc tccatgagat tcataacttt cgattggtat taatgctaca
    15121 tcttctctat tccagtttac aaaatcatca gaacttacat aagcccaatg cttcattcca
    15181 tgagttgcat catatggata ccattgataa aatacatggt acttaccatt ataatatgct
    15241 aatccatttg ggtcattaag tagtccatgt tgtggatgta tatgaaatag tggtttatat
    15301 ttatcattta aagatatatt tcttaattta tttaattctt cttttgtcga ttctaatatg
    15361 gttctatatt taggctcttt gtacatattt ttattccttt tcttttataa ttttatattt
    15421 gctttattat tactatctaa aacaattctt aatcttgtta cacaatgtgc tacacctttt
    15481 atattttatt tatttcctat gtactctaat aattactttg atactttgtt acaatcagtt
    15541 atttttgcac tcattttgct attctatcgg tttaattaaa ccggtttcga aaccggttta
    15601 attaaagatt agcataaatt tatttcagat gcaatatttc tttcaaaaaa gttttcctaa
    15661 tttttagaat tatagttttt ttagtaaaaa aatacacatt actaatatat gtaatgtgta
    15721 tcttaatttt tatttattgt actttcacct tctattaatt caaatttaat ctcctttaat
    15781 agtggttctt ttctttcttg tattaagttt actatcgtat ttgctgctac tttacctgca
    15841 tttttatttt caaactttat tgttgtaagt ttagggctta taatagacaa tacatcatat
    15901 cccccaaatc cagctacaga tatatcttgt ggtatacttt tacctctctt attgatttct
    15961 ttcattgttg ctattgctat attatcagtt gcacatatta ttatatctgg attttcactt
    16021 tctagcattt ctccacttct ttgtatagac gtttcttggt caaagtcagt ataaaatact
    16081 tttgcatcat accctttatc ttttaaccca ttaagtactc ctttttttct gtttaaacca
    16141 actgatatat cactttcatc aacacctaaa tatacaatgt ttttgtaacc tttattagca
    16201 atatattgac ccattttata tcctgctcca taatcatcat tcactatgct attgatacca
    16261 tcaacttttt gtccaactac aactatcggt atatctaact tttcaatttc attcttatgt
    16321 tctttagtta tttcggtacc aattagtatt attccatcaa cttttagact agctaatttt
    16381 gatatactat ctatttctga ccttattttt ctattagtat taataattag tgatgtatat
    16441 tttaattctt tgagttcttc atctattgcc atcataattt tagattttac aaaagaatct
    16501 aaacacggtg ttataatacc aataaagtat gtttttttag ctctcaaact ttgagcaaat
    16561 gcattcggct catatccata ttcatctatt attgtcttta ttttctcttt agtagaatca
    16621 ctgatatctt tattatttag atatcttgat acagtacttt tagatactcc tgccaagtta
    16681 gcaatatcat ttattgttat ttttttcata ggttatcacc ttctacattt gatatatttt
    16741 attacattat attatatatt taaaataaaa tatagttatt tgtccagtca atacttttta
    16801 tatactactt gtactatcca ttccacatcc aaataattga gtctttaaca ttaaattaat
    16861 tgtaattttc attttttgtt gttatattta atttcaattt tatctactat gaattgataa
    16921 atactctaat ttatttataa tataaaaata aggctatgat ttttacaacc atagccttat
    16981 cgataaacac ttaattatca cttaaaaaat aattttttat ttaaagaata tatataaata
    17041 ttttaaaatt ctataatttt taaaactata taaactttat tttcatatgt ttttattctc
    17101 caattgatat attatttatg ccattatttt taacttcaat aattggttgt ccatttccta
    17161 aaatataatc tttagaccaa ccttctggca atttatttat cccatttcca attaacttca
    17221 agtgtaaatt tgatggttct tttttcagat ttaatttaaa tattccatca aaggtacctt
    17281 tattatcgct tccaaataaa cttatattgc catttatatt cgtagctgtt acatttacaa
    17341 ttccattgtt tgctctaaat tttatttcag atgatatagt ttcagctgtt acacctgaaa
    17401 tcccactatt agtatttata ttgaaaggat ttgttacatt gttatcaaca atgttagcaa
    17461 tcccgtcatt gacatcaaca gtagctcctc ctttaatatt ataaagttct actgaaccac
    17521 tttcaacatc tactttaaaa ttagaataca ttttatcggg aactccaatt tttatcacat
    17581 ttaccatcct atctttattt gcatttatca tattgtcgcc attcatatct tgcaaatcac
    17641 tatctttctt atctattttt ttcttagcac ttacaactag ctttccattt tttatattat
    17701 tagaagaatt ttctttatat acagaaaaag tacaattttt ttcattagtt acacttacat
    17761 aatcaaactc aaatttattg gtattcgtct tttcaacaac cacacctaaa ttatctgatt
    17821 ctataagtat ttcagaaact tcatttcctt caactgaagt taagtgtttt aaaatatttg
    17881 gagtcatatc catattatta tatttaatca tatctaaaca ctgtttatat atattggcat
    17941 caatacctcc aacttttgtt atacttttag ctccttttaa aataccttta ttacttccat
    18001 cagcaactaa aacgattggt ttttctttgg ctaaaggaga taatgttagt gcatctacta
    18061 attgatatcc atttgttata taaaaatctg tcgctccatt ataaaacttt tccattacct
    18121 ttttattggt ctcaaatcta tcatttcctc cgattctagt tgctttagtt tcatttacta
    18181 aatcctcatt tatcgcagat ttgccaccta tagcgtaaac atttaaacct tcagtcttaa
    18241 atggaactga tttcccatct gtaagtatta tagctccttt attttttgca actacaggtg
    18301 ctatactcat agcatcagcc tctcctacaa atccatttgt aagcattacc tcttttacac
    18361 tacttacttc atttattttt ttagctacat tataactagt ttcaattcta ttgttaccat
    18421 ttattctttc cacttgaata ccttttcttt ttatatcttt ttctactgaa ttttcaatag
    18481 tattataacc accaattata tatacttttt ttacaacatt taaactctta ttatctagtc
    18541 tatttaaagt agcttttggt atttcacttt ttttagtcaa aagtattggt gcgttaatag
    18601 ctccagctaa tccacttgat gaaagcccat cagataaatt tttatctcca ttaactaata
    18661 ttacagtatc ataagtttgt ctatccgcta taagtcctgc tgtttcatat ctatcaattc
    18721 ctattattga atcttcttta atctgtgcat ttgcagttaa attattaaaa agaaacatag
    18781 tcaaaactaa aattaatata cttaggtttt tactgaattt tttgaatttt ttattcataa
    18841 tatacactat tcctcctgta aattaaggtc tttaatttgc ttataaatta tccccttatt
    18901 tacaaataat aacataatat tatagtaacg tatatattac cttaaaatta tcagtaattt
    18961 tatataaatc atcttagctt atttatataa atttttttat attacttttc aaataacagt
    19021 catactaaaa caatttcatc atataatttg aaaattatta ctatttacac agcttttatc
    19081 atcatcttac caccatcaaa tatatattca accatattat tctcatataa ataagttata
    19141 taagaacgta ttgtacttcc aaccaacaca tattgattag catcaagctt gacattgtac
    19201 aaatcacaca ttttttcaat aacttcatca atcataactg gttcataaca aaccttttta
    19261 atattatcta ttatttcttc catcttctcc ttattaatat taatcaaact ttttatatct
    19321 gtagttttga cagagtgact tggaacaaag aaatcagcct ctaacattct caatttttct
    19381 agtgtcttaa actgtgaatc tatatccagt aggaagaaaa aatgatattt agtaattata
    19441 ttctctggtg taagactatc tgcaacaaac aaaacattat ctggagttct aacaccaatc
    19501 gtttcaaaat aatgacctgg aagagaaatc gcttcaagtt ctgtatctac aattttgcca
    19561 tttgaaggta taatataatc aacttcactt tcctttgcta ataaaaattt attcttcagt
    19621 gctttacttg gatagccacc atataaaaat gctgattcta atattgtatt ttctgtaaaa
    19681 tatccttcaa ttttagtcgt agcaatcttg cattttgttt gattcttcaa atatgcattt
    19741 cctcctatat ggtctgcatt tgaatgagtg tttattatta atttaggact taaattatgt
    19801 tcttctaata atcttaaaat ttgtctagct gtatccttat tatttccact gtcaattaaa
    19861 attgcatctt taccatctac gtatacacct actattgtag ggagtggaat ataatatgta
    19921 tttcctttta tatgttctag agttaattta gccattttat aacctccctt taaatttact
    19981 tttaattata gcattaattt tctgaaaatt ccaatcaaat tgtttttata atatattttt
    20041 atttctttta ttaaaaattg gaaaaactat ataatatata ttataatcta tatataagga
    20101 gtgatgttat tgaaaaaaga tagaataact ttttcagaaa ttttaatatt aattgtaggc
    20161 tgtatattaa tggccatttc tcttaactta ttttttaatc cacatgcaat cgctgctggt
    20221 ggtataacag gacttggagt tgttttaaat tcattattcg gtgtagaact ttggattgtc
    20281 aatttacttt taaatgttcc attattcata tttgcttaca aaatactttc aaaaaaagat
    20341 tgttttaaaa cggttttagg aataattttt cttaccatag cacttaagct tactgcaaat
    20401 atggctacat tagatataac aaatgatatg tatcttgcaa ttatatctgg ttctatttta
    20461 atgggagttg gtcaaggact tatttttaga ataaatggct ctacaggtgg aactgattta
    20521 atggcactcc tactaaataa atattttcct acatttagta tacctgtttt aatgggtatt
    20581 gtagactgcg ttgtagttgt tttatcaggt atagtaaata gacaggttga aattgcactt
    20641 tattcaactg tggctttata cattttagta aaagttagtg acttgcttat tgaaggattt
    20701 aattattcca aatcattcac tattatatct gacctttcaa aagatataag taaaaaaata
    20761 atggaagatt tagatagagg tgcaactatt ctaaaaggag aaggtgcata tactggagaa
    20821 aataaaaatg tacttttagt agtagttgaa aagaaagaag ttgtcgaatt aaaaaaatta
    20881 gtaaaaaatg tcgaccctaa tgcttttatt ataattacag acatacatga agctttaggt
    20941 aatggattta aaaaaataga ataactaaca aataaatagc aagtataatt aacatataca
    21001 aattcaattt tttatatgtt atattatact tgctatttat atattatact ttctatttat
    21061 atattataat tgttgttttt aagataaaaa ttaaatgtat caattattgt tttatacaag
    21121 tatttccaaa tccgttctca tttagatagt atgcttagaa attttagaat tattgagtct
    21181 aactttatta cttacttcac tttataacaa tcaaatacaa atttaaatat tataaaacta
    21241 caaaataatt taaagcatat aatgtcaata tgtttaaatt ataaaatatt catgtagtta
    21301 tataataaat aatttataaa tatagccaac ttagcctaaa tacgtatata atatagctaa
    21361 tatggttctt atacttgata ccatcaataa aactaaaaat ataaaaagga gaacttaaaa
    21421 tgagtgttag tttacaaaaa ggacaaagag ttagcttagt aaaagataat aatcctgtaa
    21481 aaaatctagt agtaggctta ggatgggata tgaataaatt gggtaaaaaa aattatgacc
    21541 tagatgcatt tgcaatagca ttgactaacc aagataaaat gaatgttaga ggtgacttgg
    21601 tttattttgg aaatcttaaa cacccttcta aagctattat acacactgga gataacttaa
    21661 ctggaaaagg tgaaggtgat gatgaacaaa taattgttaa tttagaagac atacctgaat
    21721 atgtacataa aatagttttt ggagtttcta tatacaaagc taaaaaaaga gaccaggatt
    21781 ttggtcaaat gaacaactct tttataagat taattgattc aaattccaag caagaactat
    21841 ttaaatataa tcttcaagaa gacttttctg gtaaagtaac agttttggca ggagaaattt
    21901 atcgtagaaa tgaagaatgg aaatttaatg ctttaggaat tggtcaaaat gaagagcttc
    21961 gtgaattaat taatacatat aagtaataat tacaataaaa aatttataat gaggagttgg
    22021 tttaaatggg tataacttta gcaaaaggac aaaaagtaag tttaacaaaa agtaaccctg
    22081 gtctaaaaaa agtaatagta ggactaggat gggatattaa taaatatgat ggtggctttg
    22141 atttcgattt agatgcctct gcatttttaa ctggaactga tggaaaagta acgaatgatg
    22201 gagactttat attctataat aatttaaaac acgcttctgg agctgttgaa tatatgggtg
    22261 ataatagaac aggtgttggt gatggtgatg atgaacaaat aaatgtagac ttatctaaaa
    22321 tacctcaaaa tattgctaaa atatcattta gtgttactat aaatgaagca attacaagaa
    22381 gacaaaattt cggacaagtt gaaaattcat atataagaat atataatgaa gaaactaatg
    22441 aggaacttat taaatatgaa ttgggtgaag attttagcat agaaacagca atagttgtgg
    22501 cagaactata tagacataat ggagagtgga aatttaatgc tttaggttct ggatttgagg
    22561 atggacttgc aggattgtgt aaaaattttg gcgttaatat aggctaatat gtctaaataa
    22621 aaataagagt atattgatat actcttattt ttatttagat atattataaa ctgtttacac
    22681 ttctactctt ctttctcgct tgttttttcc catattctac tgaaatatca aaaaatgctg
    22741 aaatattttc tgtaaaaaac ttgcttctat gatatgcaat atcaaatgtc ctatgtaaat
    22801 taataccttc aatatcacaa gcccacaaaa gatgcttttt taaataatcc tcaataagta
    22861 attcagatat aactgcaatg ccaaaattat ctacaactgc tcttaatata gcttcagagt
    22921 tataacatga ccatctaata ttcattggga tttttaattc ttttaattgc ttttctaatt
    22981 gtgctcttgt accacttcct aattcacgca taattaatgg ttgatttgaa agttctgaaa
    23041 cttctataga gtctctttta taaaactcat gcttgtgtga acatataagt acaagattat
    23101 cattaataat gctttttgta acaatatctg ggtgcttaat ttttccttct acaatcgcaa
    23161 tatctaattc actattaagt aatttttttg caatcagtct tgtatcttct acaaatactt
    23221 caggttctat aagaggattt accttgtata attctaacat tatcgggctt attacacatg
    23281 taccaacagt tactgttgcc ccaactctta tacggatatt ttttgcacaa tgcttcatac
    23341 aatcattcat ttcttcattt acagctaaaa gatgcctccc atatccaaga agttttttcc
    23401 ctgcctcagt taaatataat ttttttgaaa ttctatcaaa tagcttaaca ccatactctt
    23461 tttctatttc tgaaatagct tggctaactg atgactgggt aatatacata tttcttgcta
    23521 cttcactcat tttaccacat tcagcaacct taacaaagat ttcaagacta cgaattgtca
    23581 tattatcaca accttagcaa acattagtaa atgcttatga ttttattaat attttagtat
    23641 tttacaaata tattgtcaag aagtataatt ttattataga gttataaagt agattggagt
    23701 gtgatatatt gtgaaagtat taattatagg tggagttgct gctggaacaa aaactgctgc
    23761 aaaaataaaa cgtgaaatgg gtgataattg ctctgttaca atactaaata aaggtgatga
    23821 tatttcttat gcaggttgtg gtcttccata ttacgttggt aagataattg aagataaatc
    23881 atctttaatc gtaaatacac ctgaaagttt ttctaaacta acaggagcag aagttcgttg
    23941 tggagttgaa gttacgtcta ttgatagaaa tgcaaaacaa gtaattttga aaacgctttc
    24001 aacaggagaa aaagaaaatc taagctatga caaacttgta attgctacag gggcagaccc
    24061 aataaaacca ccaatacctg gaatagattt acctggagta ttctttatgc gtactccaaa
    24121 tgatgctata aaactaagag attctattga aaacggtatt aagagagctg ttgttattgg
    24181 tggaggtttc attggtcttg aaattgctga aaatctttct gcaatgggta tacgtgtaag
    24241 tgttgttgat atggctgaac atgttatgcc tggatttgat actgattttg ctgaatacgt
    24301 tgaaaatcat atggctgata aaggcataat gatttttaca ggtgaccaag ttgtaggtat
    24361 tgaaggtgaa aataaagttg aaaaacttcg tactaaaaat agagctatta aaacagattt
    24421 agtggttatg tcagttggaa tccgtcctaa cacaggtttt ctaaaagaca caggtttaga
    24481 atttgcccct aataatacaa ttattgcaga tgaatatatg cttacaaatg acaaagatat
    24541 atacgtagtt ggagactgtg cttttgtaaa aaattcttta acaaataaac ctacatggtc
    24601 acctatgggg tcatctgcaa atcatgaggg tagaatttgc gcacaaaata tatctggaaa
    24661 atctaaaact tacaatggtg ttcttggaac aacagtagta aaattacctg agctcaatgc
    24721 aggaaaaaca ggtctaagta aagaaatagc tgaaaaagaa ggttataatg tttgctctgt
    24781 aaccatagct actgatgata aagctcatta ttatccaggt gcatctaatt ttattataag
    24841 aatggttgct gaaaaaaata ctagaaaatt attaggtgtt caagttatgg gacctggagc
    24901 ggttgataaa atagtagata tcgctgctac tgcaataact ttaggcgctg acctttattc
    24961 attagaaagt atggaccttg catatgcacc acctttttca acagctattc acccttttgt
    25021 agtggcagta aatgttttac aaaataaact taatggagaa cttgatagtg ttttacttga
    25081 cgaaattgag gattttgaca gttggactaa acttgatgtt tcaaaagctc cttctattcc
    25141 tagtttacgt tatattcctg ttggtgaaat taatggagaa attgaaggcc ttgctaagga
    25201 tgaaaaaatt cttcttatat gtgctaaagg taaaaatagc tatatggcgc aaaatcgctt
    25261 aagacgcttt ggctatacaa atacgaaagt tcttgaaggt ggaatactat tttatccaaa
    25321 tcttaaggta atggaggagt aaatatgagt aatgttacag cagaacaaaa aaaggaagta
    25381 aaaggtagag gttttctacc aagcagggat ggagaacatt ttgcagcacg tataataact
    25441 gtaaatggtg taataaatgc atcacaagca aaaaaaattg cagaagctgc tgaaaaattc
    25501 ggaaacggtc agttagcatt tactactaga ctaacagtag aattacctgg tgtaaaattt
    25561 gaagatattg aagctctaag tgaatttatt gctagcgaaa atctaataac aggtggaact
    25621 ggatcaaggg ttcgtcctgt tgtggcttgt aaaggtactg tttgtgttca tggtctagct
    25681 gatacacagg cacttgctgc tgaaatacac gaagaatttt acaaaaattg gtatgatgta
    25741 aaactacctc ataagttcaa aattggtgtt ggtggatgcc ctaataactg tattaaacct
    25801 gacctaaacg atcttggaat tgttggtcaa cgtgtacctg actatgattc agagctttgt
    25861 gttggttgta aaaaatgtgc tgttgtagag gtctgtcctg ttaaagcagc taaattaaca
    25921 gataaaggta aacttgaaat agatagtaat ctatgtaata actgtggtaa gtgtatagaa
    25981 agttgtaatt ttgatagtat tgaagaaaaa gaatctggtt ataaagtcta tataggaggg
    26041 aaatggggaa aatcagttcg tcctggaaca cagattgata gattattttc aaaagaggaa
    26101 cttatgactt taattgaaaa agcaattctt ttatttagag aacagggtaa cacaggtgaa
    26161 cgttttggaa taactatcga tagaatcggt gctgataaat ttatagaaat gcttttatca
    26221 gatgaagttt tggaaagaaa agaagagata ctagaggctc ttttacacct tacaggtgga
    26281 gctgtatgct aacaataaat attttaattg tacagataac ctatggaaaa aattttagtt
    26341 aagaataatt aaaattctat atatgatata tgataaatga ggctatctca aaacacagat
    26401 acgcctcttt ttcattgttg aaatgataaa gtatatttga gttcatataa aaaagagtgt
    26461 ctcgtgaatt ataaaattca ttttgaggca cccacattat tttataataa ttgcttatta
    26521 attttatttt aactatataa aatgtacaaa aagtaagaat atccaatatt ctaaaattaa
    26581 ttttgaattg tattgattga aaagtttact attccactat ttccgtcttg atttactact
    26641 agataccatg ttccagtatt aggaactttc attctacatg gatttttctt tgcaaatcca
    26701 ccatagtaat cataattttt ttgattttta aatttcacat aatttatatg gtctaacaat
    26761 attacattgg cttgtttctc taaatttacc tctacaatat cccctttttt taagttcatc
    26821 ttactataac tatattccat tgaattactc ctccagtatc gaataatctt tgttatttac
    26881 tcatctcaaa tatgtaaaaa ttcatttaaa atattacaaa tactatataa ttagactatt
    26941 atccagtttt aaccttattt actacaatcc aaaggttatt aaaaatatta ttggcaacaa
    27001 cttctccatc ccatacaact ctttcttctt tattttctaa taaagcatag tacccagagt
    27061 cagaactttc atctttatag actgtaacat aaaactcttc atcactatat tcaggtatat
    27121 ttttaaagtc ttcagatatt ttacatgtta atatataacc ttctaattct tcatctataa
    27181 acaaagcaat tcctccaatc tctatatttt tactaattat accatattat gtcataaact
    27241 ttttatttta ttacaaattt ctattttttc tttactttat aaataaat
//
LOCUS       DAEORM030000050        27105 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.050, whole genome shotgun sequence.
ACCESSION   DAEORM030000050 DAEORM030000000
VERSION     DAEORM030000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 27105)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27105)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 27105)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27105
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.050"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            98..1042
                     /gene="mobV"
                     /locus_tag="KRH23_002798"
     CDS             98..1042
                     /gene="mobV"
                     /locus_tag="KRH23_002798"
                     /inference="COORDINATES: protein motif:HMM:NF013258.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MobV family relaxase"
                     /protein_id="HHS5226076.1"
                     /translation="MAQHAILRFEKHKGNPARPLEAHHERQKEQYASNPDIDTSRSKY
                     NFHIVKPEGRYYHFIQSRIEQAGCRTRKDSTRFVDTLVTASPEFFKGKSPKEIQAFFQ
                     RAADFLIGRVGRENIVSAVVHMDEKTPHLHLTFVPLTKDNRLCAKEIIGNRANLTKWQ
                     DDFHAYMVEKYPDLERGESASKTGRKHIPTRLFKQAVSLSKQARAIEAALDGINPLNA
                     GKKKEEALSMLKKWFPQMENFSGQLKKYKVTINDLLAENEKLEARAKASEKGKMKDTM
                     ERAKLKSELDNLQRLVDRIPPDILAELKRQQRHTVKER"
     gene            1114..1308
                     /locus_tag="KRH23_002799"
     CDS             1114..1308
                     /locus_tag="KRH23_002799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226077.1"
                     /translation="MAKSESDIFTPRTGQVIQAENGTQYFVCGNNRIKISEHFAAGGK
                     PLGDLIVDVVRHTAEKAAST"
     gene            1454..3031
                     /locus_tag="KRH23_002800"
     CDS             1454..3031
                     /locus_tag="KRH23_002800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003019515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4368 domain-containing protein"
                     /protein_id="HHS5226078.1"
                     /translation="MRLSRDDELQGESGSIQTQRMMLRQYAAEHGLNVIDEYIDDGWS
                     GTNFDRPDFQRMIDDIEDGKINCVVTKDLSRLGRNYILTGQYTEIYFPSKGVRYIAVN
                     DNVDTINGENELAPFLNILNEMHARQTSKKVKAAMRTRFANGAHYGAYAPLGYVKDPD
                     KKGHLLVDPETRWIIEKIFDLAVHGRGAASITRILVEEKVPTPGWLNFQRYGTFANIY
                     AGAPEEKAYAWTIAQVKSILKEETYIGHSVHNKQTNISFKNKKKVRKPKEEWYRVENT
                     HEAIISEDVFRQVQEQICNRRRRQKNGTTQIFSGLVKCADCGWSLAYGVNSQNKNPYA
                     HFHCSKYGQGLHQCSMHYIRYDVLYAYVLSRLQYWSVLAQQDGDKLLKRLLNASDKER
                     NTARKRQTAELKKAEKRKAEVDTLFAKMYEDWSAGRITEYNFNMLSEKYQGEQRELDA
                     KIERLHEAMEAAAQTAVDAEKWIGLMKQYVNPTELTAELLNTLIEKILIHEAVKSEDG
                     SREQEVEIFYRFIGKIE"
     gene            3168..4049
                     /locus_tag="KRH23_002801"
     CDS             3168..4049
                     /locus_tag="KRH23_002801"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHS5226079.1"
                     /translation="MKEDINKLYNKLCKDFTVKPFDEVMDEIREIIKKYYSCFPLIFR
                     MGLLIVNHYDIVDEKKRELLISEALEIFIRIQETCNDIDICRQAKSMEATCYILLNQP
                     IQVIDLLQNSNFPMINESILLAQGQMMNGQMDEARETFQLGAYQNLISLVQNLVGILQ
                     NADKLQMKEIERRILAISDIFELDTLSPAIMLSSYLTQAQINLIHGDNEGAIKSLRKY
                     VDLATRDIYPIIIHGDDFFNKLDRWISEIGTGITRDDTIVKAGIVAAIKNNPMFSVLS
                     ENKEYKFLIEKLSLLEE"
     gene            4054..4254
                     /locus_tag="KRH23_002802"
     CDS             4054..4254
                     /locus_tag="KRH23_002802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLD nuclease N-terminal domain-containing
                     protein"
                     /protein_id="HHS5226080.1"
                     /translation="MENLMEYLPLLVPVIILDLILIITALVHVLRHPNYKIGNKAIWI
                     IVVLFISLIGPILYFTIGRGEE"
     gene            4251..5171
                     /locus_tag="KRH23_002803"
     CDS             4251..5171
                     /locus_tag="KRH23_002803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HHS5226081.1"
                     /translation="MMNIVSINGLSKGFGNRKIIDNLNFTVPEGSVFGFVGKNGAGKT
                     TTMKMVLGLLKPDSGTIDVCGEKVTYGKTSSNRHVGYLPDVPEFYNYMRPLEYLSLCG
                     EITGLSKKEIQIRSEELLSLVGLRNEKRRIGGFSRGMKQRLGIAQALLSRPKLLICDE
                     PTSALDPVGRKEILDIMLKIKDSTTVIFSTHILSDVERICDHVAILNKGSIALSGTLS
                     EIKSMHGKDRLLLEFASNDEIQKFKSSDGIKSLLKDSEETNMEIVLHGKDIKAIQKTV
                     ISTLAEMNLCPVKMELIELSLENLFLEVVK"
     gene            5168..5926
                     /locus_tag="KRH23_002804"
     CDS             5168..5926
                     /locus_tag="KRH23_002804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHS5226082.1"
                     /translation="MREYIAFTKKEFKENLRNYKLFSLIILFLIFGISSPISAKFMPD
                     LIAHFAPTLKVTAAPTALDSWTQFFSNISGLGMSLTLIIFCNILSNEYSKGTLVIMLT
                     KGLSRSSIVLSKFSVTVIIMTIGFWLSFLFAYGYTMYFWPTANLNHIIFSAFNLWLIG
                     IMYISVLILGCVLFRPAFASVLLVLVATLLLSLISIPKQIAPYTPNFLMSKNIDLISG
                     KVAMPEFIIPIIITVLISVVCLLAVVILFNKKPV"
     gene            6174..7247
                     /locus_tag="KRH23_002805"
     CDS             6174..7247
                     /locus_tag="KRH23_002805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF362 domain-containing protein"
                     /protein_id="HHS5226083.1"
                     /translation="MEKSKVYFCDLYSNSQNKNVPNNVRRLFDEAGFKDLIEKNDQVA
                     IKLHFGEKGNTTYMSPVAVRQVVDKVKDCEGKPFLTDTNTLYTGSRTNSVDHLTTAIE
                     NGFAYAVVNAPVIIADGLYSRNYENVKIDKKHFESVKIGGEIYNSSAMIVMSHFKGHE
                     AAGFGGALKNLAMGCASAAGKQMQHSDVTPVVKEKKCVGCGKCVNSCPTKAISIVDKK
                     AVIDSDVCYGCGECPTVCPTRAVTIQWESDSDVFVEKMAEYAYGAVSNKKDKVGYITF
                     VMNVTPLCDCVPWSGRPIAHDIGILASTDPVAIEQACYDLICKEMGHDVFKHEHPHVN
                     GTRIIDYACEMGMGSKEYELIKL"
     gene            7317..7580
                     /locus_tag="KRH23_002806"
     CDS             7317..7580
                     /locus_tag="KRH23_002806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226084.1"
                     /translation="MKIYYEKENSKKANVNNIPSVFAFNFLRNFLTSKEYEETRKEYF
                     INNLTKSQVNQAMKDLKWLFREYEGLEVITMESLDGVKTRIVL"
     gene            7786..8763
                     /gene="bioB"
                     /locus_tag="KRH23_002807"
     CDS             7786..8763
                     /gene="bioB"
                     /locus_tag="KRH23_002807"
                     /EC_number="2.8.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004076 - biotin synthase activity
                     [Evidence IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0009102 - biotin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="biotin synthase BioB"
                     /protein_id="HHS5226085.1"
                     /translation="MEKYIIKLKNKVLREKEISYEEALNLISLDTNNKNDFDILLKSA
                     NEIREYFMGRKADLCTIMNAKSGKCSEDCKFCAQSSHYKTGVEEYSLLDYNEILNRAK
                     EMESKGVHRFSLVTSGKGMSGKEFNNILNIYEGLRENTNLKLCASLGIIDYEQAKMLK
                     SAGVTTYHHNVETCRDNFHNICTTHTYKDRIKTIKDAKKAGLDVCVGGIIGMNESEEQ
                     RLKMAFEIRELNVKSFPINILNPIKNTPMENYDVLEPMEILKTTAVFRFIIPNVYIRY
                     AGGRLSLKGYDKVGFNGGVNSAIVGDYLTTVGSGIENDKKMIIEQGFEL"
     gene            8982..10004
                     /locus_tag="KRH23_002808"
     CDS             8982..10004
                     /locus_tag="KRH23_002808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HHS5226086.1"
                     /translation="MNFLSITIKEIGELAGVSKTTVSKVINNKDENISQATREKILKI
                     MKEKNYVPNKLAQSLVTKKTNTIGLLIPDIRNPFFTDVSRGVEDKANEEGYNIILCNT
                     DEDAKKEYEGIRTLSERMIDGIIFAASSNTNWKEANYKDIKIPTVLIDKKISMNKETL
                     KGIVKINNFEGAYIATKHLLDIGNKKIIYLSGPLQNEIAVDRLEGYKKALIECNLSYN
                     PAYVFEGKYKIEWGQEFIKNLEKIDFDAIFCANDLIAIGVIRGLKERGLSIPNDVSVV
                     GFDDIQTSSLISPSLTTVKQPSYDIGYKASEILINCLRGDKKESFDELIFKPELVIRD
                     STKESE"
     gene            10046..10936
                     /gene="rbsK"
                     /locus_tag="KRH23_002809"
     CDS             10046..10936
                     /gene="rbsK"
                     /locus_tag="KRH23_002809"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004747 - ribokinase activity [Evidence
                     IEA];
                     GO_process: GO:0006014 - D-ribose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HHS5226087.1"
                     /translation="MGNIVVIGSVNMDMVCSVDKRPEKGETVLGNSFFTSPGGKGANQ
                     AISASKLGANVKMISCIGEDGLGEELIRNFRTNKVDYSLVSRNNHKSSGVAVITLCEN
                     DNSIVVVPGTNELVDIELIKKNEEEIKNADIVLLQLEIPLKTINYVVNFCFENRIKVL
                     LNPAPAVKLNEDIIEKVTYLTPNEHEYKIVFDTNEGIEEVLKKYPNKLVITEGKNGAR
                     FYDGEEIKHVSCISVDVQDTTGAGDTFNGALAVAITEGKNLYTAVEYAVVVSGLSVTK
                     LGAQSGMPYKEDVEKYLNNK"
     gene            10984..11946
                     /locus_tag="KRH23_002810"
     CDS             10984..11946
                     /locus_tag="KRH23_002810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HHS5226088.1"
                     /translation="MRVRKILSLGIAGILAIGMLTGCSMEGPSKSDNKGGSDKKDLTI
                     GVSTITLQHQFFIDIDEGIKEKAKELGVKVIVNDPDQDVAKQTSAIEDFIQQNVDGMI
                     VLGTDNSAIVPAVEGAFEKMPVVTVDAVLNTENITSYVGTVSYDAGKKLGEYTKKYID
                     EKLGGKSEIAIVTDLKSQIQMQRIDGFKDALKGSANVKILNSQPGYDREESLNTVENL
                     IQSNPDVDIIYATAENSVLGAKAALESAKNKDVKIVGFDLTEEASSGITDGTILAMIQ
                     QQPKEMGRLAVEAVVKAIKGEKVEKNIPVPALLYDKENIKDFKN"
     gene            12000..13511
                     /locus_tag="KRH23_002811"
     CDS             12000..13511
                     /locus_tag="KRH23_002811"
                     /EC_number="7.5.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HHS5226089.1"
                     /translation="MSNIILKLSNIAKEFPGVRALDNVNFELFHGEVHALLGENGAGK
                     STMIKILTGAHSKTSGKFIFEGKEIENISPDISKKIGINAIYQELTVFDELTVAQNIF
                     MGKEINGKVLTNDKKMNEEAKKIFDNMGIDINPNSLVKELSIAQKQMVEIARVLSSET
                     KVLIMDEPTSSISKKETEILFRLINDLKESGVSIIYISHRMEELFEICDRITIMRDGK
                     TISTLNTKDVSSEEELVNLMIDRKLDQFFPKRKVEIKEEIMRVENLTKNNVFNDISFN
                     IRKGEILGIGGLVGSKRSEIVEAIFGLRTYDSGKIYLNNEEVKFKTPSDAIENGLGLI
                     TEDRKGTGLFLQMSVKENTTMAGLKKISKFKSIIDRKKEKEILEKYIEALKIKTPHMN
                     QVIQSLSGGNQQKAIIARWLLLQPDILIMDEPTRGIDVNAKAEIYNLMGDLVESGVSI
                     IMISSEIPELISMSDRIMVMREGHISGFLEGEEMVENNVLKLAFGGKINEFNN"
     gene            13495..14493
                     /locus_tag="KRH23_002812"
     CDS             13495..14493
                     /locus_tag="KRH23_002812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHS5226090.1"
                     /translation="MSSITKHKEEKSSLLLTKLTSAFRDQGSAAVGLVIIFIIMSVAS
                     SNFLTLDNLINVGRQISINAILAVGMTFVIITGGIDLSVGAVIALVGTFWATTVVNYN
                     APIWVGMILALAIGTILGVIKGAIISTQKLPPFIVTLAMLTIISGASFVFTGGRPISV
                     NTDAFKMLGRGYIGPIPIPVIIMIIVVIAGHFLLKRTNFGRHVHAVGGNEEAARLCGV
                     KVNKVIVKVYALAGLLTALAGIILSSRLASGSPTVGDGAELDAIAAVVLGGTNMMGGS
                     GSIVGTCIGVGIIGILGNGLNLLSVSSYNQMIIKGLVMLFAIWINNIKLKKSAKSK"
     gene            14677..15939
                     /locus_tag="KRH23_002813"
     CDS             14677..15939
                     /locus_tag="KRH23_002813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HHS5226091.1"
                     /translation="MKKILLDTLNSKKQEYIDYLKELVSIKTEDVGHGILGGFEKEGQ
                     EYIEKLANYIGFSVDRQEMSEELIKKAKNIYKEGNLGHNYQDRYNLICKYSDDLPGKT
                     IVFNGHVDTMPPGDISKWKYNPYRATEDNGKLYGLGTADMKSGLIASILAVKLIKDSG
                     LNVPGNVKIMSVVDEEGGGNGTINAVMNGIGGDYCIICEPSEQNLIVAHMGFVFFEVE
                     VKGVSLHCGSKWEGVNAIEKAMLLLQDIKELEHNWLMIYKHPLLPSPTINLGVINGGT
                     AGSTVPDKCVFNLCVHFLPNIMSYEQVVNDVTNVIMTRANGDLWLKDNKPNINIYQSG
                     LGFEMDKDSDFVVNAHKILEETLGKKLEIKGSTAGNDARLMKNLAEIPTLILGPGSIE
                     QCHSIDEYVEIKEYLDSILMYASIILNL"
     gene            15959..16702
                     /locus_tag="KRH23_002814"
     CDS             15959..16702
                     /locus_tag="KRH23_002814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine amidotransferase"
                     /protein_id="HHS5226092.1"
                     /translation="MKKVLIVGESWVKNITHIKGFDTFVTTHYEEAVKWLKEAIESGG
                     YETVHMPAHVAADSFPYKLEELNEYDCIILSDIGSNTFLLSNSTFIDCNSNPDRLELI
                     KEYVNNGGALIMVGGYMSFTGIDAKARFGETAIKDVLPITMIDKDDRVEKPAGIIPEV
                     IESEHPVLKGIPTEWPKFLGYNKTVARDNCPVLATIGGDPFVAVGEFGKGKSAIFSSD
                     CAPHWGPKEFTDWKYYNKLWVNMLDWLTC"
     gene            16875..18260
                     /locus_tag="KRH23_002815"
     CDS             16875..18260
                     /locus_tag="KRH23_002815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HHS5226093.1"
                     /translation="MDNLNKKFLMEYIDEIQGELRDISDRIWKNPELQYKEYYASNLQ
                     KECLKKHGFSIEGLEGMDTAFVASYGEGRPVIAVLGEYDALDGLSQKVSTIKEPIVDG
                     GAGHGCGHNLLGTGSIGAVIAVKELIKLKKLKGTIKYYGCPAEEDLSGKVLMIKKGFF
                     DGIDCAFSWHPFDINTPIRIPTLANYSVKFRYNGISAHAAQAPYNGRSALDAVELMNI
                     GCNYLREHIFDNCRVHYVTTNGGKMPNIVPDFAEVWYYIRGVKMEHVRDVFGRIVDIA
                     KGAALMTGTIMEYDIISGVYDYIPNTILTDILSQNMKLVGVQNYNEDDYYFADKLAET
                     VSIDKRSSVSSVLSGNKDITKMNLHDEVTDDTFTHNNCISLSLDIGDVSYIIPTAQCS
                     CSVWPIGISAHTWQSCASAGSDMGFKAMLLASKSISCSINDVMLDESVINKAKKELKD
                     TVGSFKYIPII"
     gene            18479..19318
                     /locus_tag="KRH23_002816"
     CDS             18479..19318
                     /locus_tag="KRH23_002816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5685 family protein"
                     /protein_id="HHS5226094.1"
                     /translation="MFGYVKINKMDLTFREYDYYKAYYCGLCKYLKRNHGEISRFSLN
                     YDITFLIVLLTAVYNPESISTEEVCIVNPFKKKKVITNDITEYAASMNILLTYYKLED
                     NLMDDKRIKDKLAYYIYKNKLKLAYEKYPEKAEYIKQQLNELNKLEKDKNINIDEVSS
                     IFGNIMGEVFVYKKDENERNLRMIGFNIGKYIYLLDAYEDLDEDFKKGRYNPFIEYID
                     KNNELKEKVKKIIVTSLGFLARGIDNLNLNKNVGIIENIIYSGVYLRYINILESRGGK
                     NVQ"
     gene            19308..19751
                     /locus_tag="KRH23_002817"
     CDS             19308..19751
                     /locus_tag="KRH23_002817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226095.1"
                     /translation="MYSNTYNNENFMRARSFIENSEFKKAYDFLKTLTDKCAEWYYLT
                     GFSAMNIGYYEEGEDFLKRAKFMEPENSEYSDALRSYTQYRNDYSNRADNYNRRRRND
                     LDGCCCCCCDDCCCCLGDDCCENCAKLWCLDSCCECFGGDLITCC"
     gene            19762..20253
                     /locus_tag="KRH23_002818"
     CDS             19762..20253
                     /locus_tag="KRH23_002818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226096.1"
                     /translation="MSIKVAYGGVLLALNVILLTLTNIIPVNTLFIMGLASLLVSIVI
                     MEWGFKSGIAFYIGSIVLGFIVMASKSQWIVYSLTFGIYGIVKYLIEKDRSIYIEYFM
                     KLVFANIMILILYFLLRTIVYIPINIFIIGSFEIAFIVYDYVYSSFIGYYNNRLRKML
                     FKK"
     gene            complement(20455..21183)
                     /locus_tag="KRH23_002819"
     CDS             complement(20455..21183)
                     /locus_tag="KRH23_002819"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HHS5226097.1"
                     /translation="MKNIAAFFDIDGTLYRDSLMVEHFKKLIKYDIIDQKNWYKHARD
                     TFMDWDKRQGNYDDYLLEICDLYVDSLKGLDKTCINFTSDQVIKLKADRVYKYTRSRI
                     EWHLNQGHIVIFISGSPGFLVEKMAKKYNVTDFLGSDYVFENNIFTGTVIPMWDSISK
                     NNAINDFVVKYDLDLSNSYAYGDTNGDINMLKRVGNPIAINPTKELLSQISLDEEISK
                     NVEIIVERKDIIYSLSTDVNIVDI"
     gene            21308..22396
                     /locus_tag="KRH23_002820"
     CDS             21308..22396
                     /locus_tag="KRH23_002820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226098.1"
                     /translation="MNFNFAKATNSRLMGSLGLIINWIDDENNHFCQYFLLDAEGLGL
                     ADYVSLNNPTQEEAYMEEERLMGGFGSDRVELTKDESLFLVSYFGNKNLYYDKLLPGD
                     KCEYIDIIKNYKTDLTIEKLYNKICKRVDEEVEFINYMTMRFIAWDRESLKYFSGSDE
                     IANMHITNINGTLLKNVVSDKGQGRYISEALYEDNDGYYICKIAFCISKCYETGFRIN
                     SLLVTDKEPMYDFEVFDEISKSEFVSVYSVNSPEEFAGVFYRENPFLLKSNMNEGIFF
                     TRFNFNNDHVKENVYIINNDMKAIYYLMGNKFFIGTYNENDCNYINEISQSNYSDYIK
                     FEEKFFFEQNALYDFAESGSLDFDDFLE"
     gene            complement(22833..23681)
                     /locus_tag="KRH23_002821"
     CDS             complement(22833..23681)
                     /locus_tag="KRH23_002821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226099.1"
                     /translation="MSNKKKKDLDTSYMPYLDPANYADYITNEEIPQDELRNDPQISN
                     GYTKIPNNQNINNLYPNNVNHYPKSSNSPNNLPNTNNTSGNMNYNTSATNNMPNNMNN
                     NTGMPNNMSNNMNSNMGMPNNMSNNMNSNMGMPNNMPNNMNSNMGMPNNVPNNMNSNM
                     GMPNNMSNNMNSNMGMPNNMSGNMNNNMYGNTGMPNNMNSNMGYNMNNTMGIPNFSCN
                     QNMPPNVLMMIPGVICHNTMQGMPVVMPSTMPPNIYPTPYGSSNMSVQGIPQATNIEE
                     FDEEEM"
     gene            23880..24245
                     /locus_tag="KRH23_002822"
     CDS             23880..24245
                     /locus_tag="KRH23_002822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR/SmtB family transcription factor"
                     /protein_id="HHS5226100.1"
                     /translation="MREEINDCNCNIVHEEIVTEAKSTMPDEEMLYDLAELFKVFGDT
                     TRVKILYALFANEMCVCDIASLLNMTHSAISHQLRVLKQARLVKFRREGKTVYYSLDD
                     SHISQIFDCGLNHIRETYK"
     gene            24268..26655
                     /locus_tag="KRH23_002823"
     CDS             24268..26655
                     /locus_tag="KRH23_002823"
                     /EC_number="7.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015662 - P-type ion transporter activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0019829 - ATPase-coupled monoatomic cation
                     transmembrane transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0140358 - P-type transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HHS5226101.1"
                     /translation="MEANNSIKKEFILGGLNCAHCAEEINNKVSKLQEVKSSNLNFIN
                     KKLTVNIKESFNEDTTIEKIIDIIDSTEPGLDIQISSKENAASKTSIKKELILGGLNC
                     AHCAEEINNKVSKLKEVESSNLNFVNKKLTVNISNNFEEDDVINKIKEIINSTEPGLD
                     IQVGSTDKVKGRTTEKSGAVNDTNKKELIPLIIGALVYIFGIYQTATGYESQFSNIVF
                     IVAYVIVGGDVLLRAIRNISKGRVFDENFLMALATVGALAIGELSEAVGVMLFYKVGE
                     YLQGVAVGKSRKSITSLMQIRPDYANLKVNSEVKVVSPEEVNVGDIIVVKPGEKVPLD
                     GVVVDGVSMLDTSALTGESVLREVEKGDEILSGVINKNALLSIEVTKSFGESTVSKIL
                     DLVENSSIKKSKTENFISKFSRYYTPIVVIAALLIAFVPPLVISGEVFSDWLYRGLIF
                     LVVSCPCALVLSIPLSFFSGIGFASKNGILIKGSNYLEALRSVDTVVFDKTGTLTKGV
                     FNVTKLNPEGISEEELLEYAAIAEVNSNHPIAKSILSYYNKKIDLDTIDSYEEIAAYG
                     IRVKHNGNFILAGNEKLMKKENISYSSAKEVGTVVYIAVDKVYRGYIVISDEVKEDSK
                     NAIRSLKEIGVKEVVMLTGDNEKVAKNIAQELELDTVYSNLLPNEKVDRLEDLYEGRT
                     EKEKIAFVGDGINDAPVLARADVGIAMGGLGSDAAIEAADVVLMTDEPSKISKAIEIA
                     NKTNKIVWQNIIFALGVKIIVMILGAGGVATMWEAIFADVGVALIAVVNAMRAMR"
BASE COUNT        10305 a         3218 c         5176 g         8406 t
ORIGIN      
        1 tttatattct atccattcca atcctatccg agctattttc tgcgggattt tccctgtgga
       61 aaaccccgga taggaaagga atggggaaag gagcagaatg gcacaacacg caattttacg
      121 gtttgagaag cacaagggca acccggcaag gccgctggaa gcccatcacg aaagacagaa
      181 agaacagtat gccagcaatc ccgacattga cacaagccgg agcaaataca acttccatat
      241 cgtcaagccg gagggacgct attaccactt cattcagagc cggattgagc aggccgggtg
      301 ccgaacccgc aaggacagca cacggtttgt cgatacgctg gtaactgcca gcccggagtt
      361 tttcaagggg aaatccccaa aggagataca ggcgtttttc cagagggcgg cggacttcct
      421 cattggccgg gtaggacggg aaaatatcgt gtcggcggtg gtacacatgg acgagaaaac
      481 gccccacctg catttgacct ttgttccgct gacaaaggac aaccgcctgt gcgctaaaga
      541 gattatcggc aaccgggcaa acctgacgaa gtggcaggac gattttcacg cctatatggt
      601 ggagaaatat cccgacttgg agcgtgggga gagtgccagc aagacaggcc ggaagcatat
      661 ccccacccgg cttttcaaac aggcggtttc cctctccaaa caggccagag ccattgaagc
      721 cgcccttgac ggcattaacc cactgaacgc cggaaagaaa aaagaggaag ccctctccat
      781 gctgaaaaag tggttcccgc agatggagaa cttctccggg cagttgaaaa agtacaaggt
      841 cacaatcaat gacctgttgg cggagaatga gaagttggaa gcaagggcaa aggccagtga
      901 aaaaggcaag atgaaagata cgatggaacg ggcaaagctg aaaagcgaac tggacaattt
      961 acagcggctg gttgaccgta tcccgccgga tatactagcg gaactgaaac ggcagcagcg
     1021 gcacacggta aaggaaaggt gatagtataa gcagaaattt tcgccgcctc tgtgcggcat
     1081 tgtaccttga aaactgaata tggaggacac tggatggcaa aaagcgaaag cgatattttt
     1141 acaccccgga cagggcaggt catacaagca gagaacggca cgcagtattt tgtatgtggg
     1201 aacaaccgta taaaaatctc cgaacacttc gccgcaggcg ggaagcccct cggtgatctg
     1261 attgtagatg tggtgcggca taccgcagaa aaagccgctt caacctgata gcccatcatt
     1321 gataacacgc ccacgcttat gatataattg ccatagagca aaagtattgt aagcgtgggt
     1381 tgtttcttta gaaggaggat ttttaacggt gaaacaacct tacaatacta cgatttacaa
     1441 cacggcgctt tatatgagat tgagccggga cgatgaactg caaggagaaa gcgggagtat
     1501 tcagacacaa cgcatgatgc tccggcaata tgccgccgag catggcctga atgtcataga
     1561 tgaatatatc gacgatggat ggtctggaac gaactttgac aggccggatt ttcagagaat
     1621 gattgatgac attgaggacg ggaaaatcaa ctgcgttgtt acgaaggatt tatcccgctt
     1681 aggcagaaac tacattctga ccggccaata cacggaaatc tactttccca gcaaaggcgt
     1741 ccgctatatc gctgtcaatg acaatgtgga caccatcaac ggagagaatg agcttgcccc
     1801 attcctcaac attctgaatg aaatgcacgc ccgccagacc agcaaaaagg taaaagcggc
     1861 catgcggaca cggtttgcaa atggcgcaca ctatggagcc tatgccccgc tgggctatgt
     1921 caaagacccg gataagaaag gtcatctttt ggttgacccg gaaacaaggt ggattatcga
     1981 aaagattttt gaccttgccg ttcatggtcg gggagccgcc agcattacac ggattttggt
     2041 cgaagaaaaa gtacctactc ccggctggct gaatttccag agatacggca ctttcgcaaa
     2101 tatctatgcc ggagcgccgg aggaaaaagc ctatgcgtgg acgatagcgc aggtaaaaag
     2161 tattctgaaa gaggaaacct atatcggaca cagcgtccac aataagcaga ccaacatttc
     2221 attcaaaaac aagaagaaag tacgcaagcc aaaagaggaa tggtatcgtg tggagaacac
     2281 ccacgaagcg attatttccg aagatgtgtt ccgtcaagta caggagcaga tttgcaacag
     2341 gcgcagacgg cagaagaacg gcacaacgca gatattttcc gggctggtaa aatgtgcgga
     2401 ctgcggttgg tcgctggcct atggtgtgaa cagtcagaac aaaaatccct atgcccactt
     2461 ccattgtagc aagtacgggc aaggattgca ccagtgttcc atgcactata tccgttatga
     2521 tgtgctttac gcctatgtcc tttcccgtct gcaatactgg tctgtgctgg cacagcagga
     2581 cggggacaaa cttctgaaac ggctacttaa cgccagcgac aaggaacgca atactgcaag
     2641 gaagcggcag acagccgaac tgaaaaaggc ggaaaaacgc aaagcagaag tagacaccct
     2701 gtttgcaaaa atgtatgagg actggtctgc cggacgcatt acagaataca atttcaatat
     2761 gctgtccgaa aagtatcagg gcgaacagcg agaattggac gcaaaaattg aacggcttca
     2821 cgaagcgatg gaggccgccg cccagacagc ggttgacgct gaaaagtgga taggtctgat
     2881 gaaacagtat gtcaatccca cagaattgac ggctgaactt ctgaatacgc tgattgaaaa
     2941 aatccttatc catgaagcgg tcaaaagtga ggacggaagc cgggaacagg aggtagaaat
     3001 cttctaccgc tttatcggca aaatcgaatg acacatcttg agatacccaa caatatcttt
     3061 aactaaggga aactggacaa agctatcctg acataacctt tttaccgcaa ctcgcgacat
     3121 atttcaacat taccgttgat gagttaatat gttatgaacc tcaaatgatg aaggaagata
     3181 ttaataaact gtataataaa ctgtgcaaag actttacggt taaaccattt gatgaagtca
     3241 tggatgaaat aagagaaatc ataaaaaaat attattcatg ttttcctttg atttttcgga
     3301 tgggtctttt aatagttaat cactatgata ttgtagatga aaaaaagcgt gaactattaa
     3361 ttagtgaagc attagaaata tttattcgta tacaggaaac ttgtaatgac atagatattt
     3421 gccgtcaagc aaaaagtatg gaggcaactt gttatatatt gttaaatcaa cccatacaag
     3481 tgattgattt attgcaaaac agcaattttc ccatgataaa tgaatctata cttcttgcac
     3541 aagggcaaat gatgaatggt caaatggatg aagcaagaga aacatttcaa cttggtgcat
     3601 atcagaacct tatatcatta gtccaaaatc tagtgggtat tttgcaaaat gcagataaat
     3661 tacaaatgaa ggaaatagaa agacgtattc tagcaatttc agatatattt gagcttgata
     3721 cattatctcc tgctattatg ctttcttcat atttaacaca ggcacaaatt aatttaatac
     3781 atggtgataa tgaaggagct attaaatcat tacgaaaata tgtagattta gcaacacgtg
     3841 atatataccc aattataata catggggatg acttttttaa taaacttgac agatggattt
     3901 ctgaaattgg aacaggtatt acacgtgatg atacaatcgt aaaagcaggt attgttgctg
     3961 ctattaaaaa taatccaatg ttttctgtat taagtgaaaa caaagaatac aaatttctta
     4021 tagaaaaatt atctttattg gaggaataag attatggaaa atttgatgga atacttacca
     4081 cttttggttc ctgttattat tttagattta atacttataa ttactgcact tgttcatgtg
     4141 ttgagacatc caaattataa aattggaaat aaggcaatat ggattattgt agtactgttt
     4201 attagtttaa taggaccaat tttgtatttt acaataggaa gaggtgaaga atgatgaata
     4261 ttgtctcaat aaatggatta tcaaaaggtt ttggtaatcg aaagataata gataatttaa
     4321 attttactgt accagaaggg tcagtctttg ggtttgtagg taagaatggt gcaggtaaga
     4381 ctacaacaat gaaaatggta cttgggttac ttaaaccaga tagtggaact atagatgttt
     4441 gtggtgagaa agtgacctat gggaaaacaa gttctaatcg tcatgtaggt tatctgcctg
     4501 atgttccaga gttttacaat tatatgagac cacttgaata tctttctctt tgtggtgaaa
     4561 ttacgggact ttcaaaaaaa gaaatacaga taaggagtga agagttgtta tcacttgtgg
     4621 gtcttagaaa tgaaaagaga cgaataggtg ggttttctcg tggaatgaag caacgacttg
     4681 gtatagctca agctttgctt tcacgcccca aattacttat ttgtgatgaa ccaacaagtg
     4741 cacttgaccc tgttggtcga aaagaaatat tagatattat gcttaaaatc aaagactcaa
     4801 caactgtaat attttcaaca catatactat cagatgttga aagaatctgt gaccatgttg
     4861 ctatattaaa caaaggaagc attgccctta gtggtacact ttcagaaata aaaagtatgc
     4921 acggaaagga tagactttta ctggagtttg caagtaatga tgaaattcaa aagtttaagt
     4981 ctagtgatgg tattaaatcc ttactaaaag attcagaaga aactaatatg gaaattgttt
     5041 tgcatggtaa agatataaaa gcaatacaaa aaacagttat atctacactc gcagaaatga
     5101 atctttgtcc agtaaagatg gaactaatag aattatcact tgaaaattta tttttggagg
     5161 tagtaaagtg agagaataca tagcatttac aaaaaaagaa tttaaagaga atttaagaaa
     5221 ttataaatta tttagtttaa ttattttatt tctaatattt ggtataagta gtcctatttc
     5281 tgcaaaattt atgccagact tgattgctca ttttgcaccg actttaaaag ttactgctgc
     5341 accaactgct ttagattctt ggacacaatt ttttagcaat atctctggtc ttggtatgag
     5401 tttaactcta attatttttt gtaatatttt atcaaatgaa tattctaaag ggacacttgt
     5461 tattatgctg actaaaggtt tatcacgttc atctatagta ttgtctaaat tctctgttac
     5521 ggtgattatt atgacaattg gtttttggtt gagtttttta tttgcttatg gatatacaat
     5581 gtatttttgg ccaactgcaa atcttaatca tattatattt tcagcattta atttatggct
     5641 tataggaatt atgtatatta gtgtattaat tcttgggtgt gtactattta gaccagcatt
     5701 tgccagtgtt ttacttgtat tggtggcaac tcttttattg agtttaattt ctattcctaa
     5761 acagattgca ccttatactc ctaatttctt gatgtcaaaa aatatagact tgatttcagg
     5821 gaaagtggca atgccagaat ttattattcc aattattata acagttctta tttctgtagt
     5881 atgtttacta gcagttgtta ttttatttaa taaaaaacca gtttaataat acctttatca
     5941 caaggtaaag taatcttatg ttgttaaaaa ctacacctaa aaatcaaaaa gacttggact
     6001 taagtttcaa gtctttttga tttttaatat atagaattaa gtgtagaaaa taatacaaat
     6061 aatattattt gtatcaaata aatataagaa tatttaatta tgttaaaata tactaaaaat
     6121 tactttaaaa gtgataaaat tagtataagt aaatatttta aaggggtgta gatatggaaa
     6181 agtcaaaagt atatttttgt gatttatact caaattcgca aaataaaaac gtaccaaaca
     6241 atgtaagaag attatttgat gaagcaggat tcaaagattt aatagaaaaa aatgaccaag
     6301 tcgcaattaa acttcacttt ggagaaaagg gaaatactac atatatgagt cctgtggcag
     6361 ttagacaagt ggttgataag gttaaagact gcgaaggaaa gccattttta acagatacaa
     6421 atacactgta tacagggagt agaacaaatt ctgtagacca tcttacaact gctatagaaa
     6481 atggatttgc ttatgcagtt gtaaatgcac cagtaataat tgcagatgga ttatatagta
     6541 gaaattatga gaatgtaaaa atagacaaaa aacattttga aagtgtaaaa ataggtggag
     6601 aaatttataa ttcttctgca atgatagtaa tgagtcattt taaaggtcat gaagcagcag
     6661 gttttggagg agcattaaaa aacttagcta tgggatgtgc aagtgcagca ggaaaacaaa
     6721 tgcaacattc tgatgttact ccagtagtaa aggaaaagaa gtgtgtaggt tgtggaaagt
     6781 gtgttaattc ttgtcctaca aaagctataa gtatagtgga taaaaaagca gttatagatt
     6841 ctgatgtatg ttatggatgt ggagaatgtc caactgtctg tccaactaga gcagtaacta
     6901 tacaatggga aagtgactca gatgtgtttg tcgaaaagat ggcagaatac gcttatggag
     6961 cagtatcaaa taaaaaagac aaggtagggt atataacttt tgttatgaat gtaactccac
     7021 tttgtgattg tgtaccttgg tcaggtagac caattgccca tgatatagga atattagcat
     7081 caacagaccc tgtagctatt gaacaagcat gctatgattt gatttgtaag gaaatgggtc
     7141 atgatgtttt caaacatgaa catcctcatg taaatggaac tagaataata gactatgcat
     7201 gtgaaatggg tatgggaagt aaagaatatg aattaataaa attataagaa tagtagcact
     7261 taaatgcata taattattgt aagagaaatc taaaagtatc aaaggagtat gcatttatga
     7321 aaatttacta tgagaaggaa aacagcaaga aggctaatgt aaacaatatt ccaagtgtat
     7381 ttgcgtttaa ttttctaaga aactttttga ctagcaaaga gtatgaggaa actagaaaag
     7441 aatattttat aaataatcta acaaaaagtc aggttaatca agccatgaag gatttaaaat
     7501 ggctatttag agaatatgaa ggcttagaag ttattacaat ggaaagcttg gatggagtta
     7561 agacaaggat agttttataa accagtaaga attatattct aataaaaaat actgctttaa
     7621 taataatatg tataatctat atactaatat tattttgaag cagtattttt ttgtgtatag
     7681 taaacttgta tctaaaataa agttgaccaa taaatgttat atatgcaata ctatatataa
     7741 taagtaaact acataaaaat attaagttga caaataggag gatatatgga aaaatacata
     7801 ataaaattaa aaaataaagt attgagagaa aaagaaataa gttatgaaga agctcttaat
     7861 ttaataagcc ttgatacaaa taataaaaac gattttgata ttctattaaa atctgcaaat
     7921 gaaataagag aatattttat gggaagaaaa gcagatttat gtacgataat gaatgctaaa
     7981 tctggcaaat gtagtgaaga ctgtaaattt tgtgctcaat catctcatta taaaactggt
     8041 gtagaagaat attcattatt agattacaat gaaatcttaa atagagctaa agagatggag
     8101 agtaaaggag tgcatagatt ctcattggtt acaagtggta aaggtatgtc aggaaaggag
     8161 tttaataata ttttaaatat ctatgaagga ttgagggaaa atactaattt aaaattatgt
     8221 gcatctttag gtattataga ttatgagcaa gctaaaatgt tgaagtcagc aggtgtgact
     8281 acatatcacc acaatgttga gacgtgtaga gataattttc ataatatatg tacaacacac
     8341 acatataaag ataggataaa aactataaaa gatgctaaaa aagctgggct agatgtatgt
     8401 gtaggcggta taattggaat gaatgagagt gaagaacaga gactaaaaat ggcttttgaa
     8461 atacgagaat taaatgtaaa atcatttcca ataaacattt taaatcctat taagaataca
     8521 ccaatggaaa attatgatgt attagaacca atggaaatac taaaaacaac agcagtattt
     8581 aggtttataa ttcctaatgt gtacataagg tatgctggtg gaaggctatc attaaaggga
     8641 tatgacaaag ttggatttaa tgggggagta aattctgcaa ttgttggtga ttatttgaca
     8701 actgttggaa gtgggattga aaatgataaa aaaatgatta tagagcaagg atttgaactt
     8761 taataaatac tgcttaaatt aattaatata cttttagata attataaaag tatattaatt
     8821 ttttttgcag attaatttaa atattaaaat tgaattataa gttgcaatat tttgaaaaaa
     8881 gggaaaaata tcaaaattta tataaaatgg ttgcaaatgg aaaaaagatg tgatagtatc
     8941 taggtaaccg gttaagtaaa acggtttcct aaattttggg ggtgaacttc ttgagtataa
     9001 ctataaaaga aattggcgaa ttggctggtg tttctaaaac aactgtgtca aaagtcatta
     9061 ataataaaga tgaaaatata agtcaggcaa caagagaaaa aattttgaaa ataatgaagg
     9121 aaaaaaatta tgtaccaaat aaattagcac aaagtttagt aactaaaaaa actaatacta
     9181 tagggcttct tataccagat atacgaaatc cattctttac agatgtatca agaggtgtag
     9241 aagacaaagc taatgaagaa ggttacaata taattttatg taatacagat gaagatgcta
     9301 aaaaagaata tgaaggaata agaacactat cagagaggat gatagatgga attatatttg
     9361 cagcatcttc aaatacaaac tggaaagaag caaattataa agatataaaa ataccaactg
     9421 tcttgattga taagaagata agtatgaaca aagaaacctt aaaaggaatt gttaaaataa
     9481 ataactttga aggggcctat atagctacaa aacatttatt agatattgga aataagaaaa
     9541 taatatacct aagtggtcca cttcaaaatg aaatagcagt agatagatta gaaggatata
     9601 aaaaggctct aatcgagtgc aatttaagct acaatcctgc ttatgtattt gaaggaaaat
     9661 ataagattga atggggacaa gaatttataa aaaatttaga aaagatagat tttgatgcaa
     9721 tattttgtgc aaatgatttg attgcaatag gtgtcataag aggtcttaaa gaaagaggat
     9781 taagtatacc aaatgatgta agtgtcgtgg gatttgatga tattcaaaca tcaagtctaa
     9841 taagcccttc tcttaccaca gtaaaacagc cgtcttatga tataggatat aaagccagtg
     9901 aaatattgat aaattgttta agaggagata aaaaagaatc gtttgatgaa ttgattttca
     9961 aaccagaatt agtcataaga gattcaacaa aagaaagtga ataacagcac gagagacata
    10021 aatagatatg taaaggagta atgtaatggg aaacatagtt gtcataggaa gtgtaaacat
    10081 ggacatggta tgttctgtag ataaaagacc agaaaaagga gaaacagtat taggtaatag
    10141 tttttttaca tcacctggag gaaaaggggc taatcaagct atatcagctt ctaaactagg
    10201 agcaaatgta aaaatgatat catgcatagg ggaagatggc ttaggagagg agttaataag
    10261 aaattttaga accaataaag ttgattatag tttagtatcc agaaataatc acaaaagttc
    10321 tggtgttgct gttataacat tatgtgaaaa tgataatagt attgttgttg taccagggac
    10381 gaatgagcta gtagatatag aattaattaa aaagaatgaa gaagagataa agaatgcaga
    10441 tatagtattg ctacaattag agattccatt aaaaacaata aattatgtag tgaatttctg
    10501 ttttgaaaat aggattaagg ttttattaaa tccagcacca gcagtaaaac taaatgaaga
    10561 tataatagaa aaagtaactt acttaacacc aaatgaacat gaatataaga tagtttttga
    10621 cacaaatgaa gggatagaag aagtattaaa aaaatatcca aataaacttg taataacaga
    10681 aggaaaaaat ggagctagat tttatgatgg tgaggaaatc aagcatgtat cttgtataag
    10741 tgttgatgtt caagatacca caggagcagg agatacattt aatggagcat tggcagtggc
    10801 tataacagaa gggaaaaatt tatatacagc agtagaatat gcagtagtag tatcaggtct
    10861 ttctgtaact aaactaggtg cacaatctgg tatgccttat aaagaagatg ttgaaaaata
    10921 tttaaataat aaataaaaat ctaatttgtt caaatttaaa actattaaaa atggaggtta
    10981 attatgagag tgagaaaaat tttatcttta ggaattgctg gaatactagc aataggaatg
    11041 ttaacagggt gttcaatgga aggaccaagt aaatcagata ataaaggtgg ttcagacaag
    11101 aaagatttaa ctattggagt atctacaata actcttcaac atcaattttt tatagatatt
    11161 gatgagggaa taaaagaaaa agctaaagaa ttaggtgtga aagttatagt aaatgaccca
    11221 gaccaagatg tagctaagca aacatcagca atagaagatt ttatacaaca gaatgtagat
    11281 ggaatgatag tacttggaac tgataattcg gctatagtac cagcagtaga aggagcattt
    11341 gaaaaaatgc cagtagttac agtagatgct gtattaaata ctgaaaatat tacaagttat
    11401 gtaggaacag ttagttatga tgctggtaaa aaattagggg aatacactaa aaaatacata
    11461 gatgaaaagt taggtggaaa gtcagaaata gcaatagtga cagatttaaa atctcaaata
    11521 caaatgcaga gaatagatgg atttaaagat gcattaaaag gttcagcaaa tgttaagata
    11581 ttaaattcac aaccaggata tgacagagaa gaatctctta atacagtaga aaacttaatt
    11641 caatctaatc cagatgtaga tataatatat gcaacagctg aaaatagtgt actaggagct
    11701 aaagctgcac ttgaatctgc aaaaaataag gatgttaaga ttgtaggatt tgacttaact
    11761 gaagaagcat caagtggaat aacagatgga actattcttg ctatgattca acaacaacct
    11821 aaagagatgg gacgtttagc tgtagaagca gtagtaaaag ctataaaagg ggaaaaggta
    11881 gaaaagaata taccagtacc agctttactt tatgataagg aaaatataaa agactttaag
    11941 aattagtaaa ataaaatgag attatttgaa agaaatccta tttaaaaagg agtgtcatta
    12001 tgagtaatat aattctgaag ttaagtaata ttgctaaaga atttcctggt gtcagagcat
    12061 tagataatgt taattttgag ttatttcatg gcgaagttca tgcactactg ggtgaaaatg
    12121 gtgctggtaa atcaacaatg ataaagattt taactggagc acattcaaaa acttctggaa
    12181 aatttatttt tgaaggcaaa gaaatagaga atatatcccc agatatctct aaaaagatag
    12241 gtataaatgc catatatcaa gaactaacag tttttgacga attaacagta gcacaaaata
    12301 tttttatggg aaaagaaata aatggcaaag tcttaaccaa tgacaaaaaa atgaatgaag
    12361 aggctaaaaa gattttcgat aatatgggaa tagatataaa tccaaatagt ttagtcaaag
    12421 agcttagtat agctcaaaaa caaatggtag aaatagcaag agttttatca tcagaaacta
    12481 aagtattaat aatggatgaa cctacttctt caataagtaa aaaagagact gaaatacttt
    12541 ttagacttat aaatgattta aaagagagtg gagttagtat aatatatata tcccatagga
    12601 tggaagaact ctttgagatt tgtgacagaa taactataat gcgagatggg aaaacgattt
    12661 cgactttgaa taccaaagat gtatcgtctg aggaagaatt agttaattta atgatagata
    12721 gaaagctaga ccaatttttc ccaaaaagaa aagtagaaat aaaagaagaa attatgcgag
    12781 tggaaaatct aactaagaac aatgttttta atgatattag ctttaatata agaaaaggtg
    12841 aaatattggg aataggtgga ctagttggaa gtaagagaag tgaaatagta gaagctatat
    12901 ttggacttag aacatatgat tctgggaaaa tatatttaaa caatgaagaa gtaaagttta
    12961 aaactccatc agatgcaata gaaaatggac taggattaat aacagaagat agaaaaggta
    13021 ctggattgtt tttacaaatg agtgtcaaag aaaacacaac tatggctggg ttaaaaaaga
    13081 tatctaagtt taaatcaatt atagatagaa aaaaggaaaa agagatttta gaaaaataca
    13141 tagaagcttt aaagataaaa acaccacata tgaatcaagt tatacaaagt ttaagtggtg
    13201 gaaaccaaca aaaagctata atagcaagat ggcttttatt acaaccagat atattaatta
    13261 tggatgaacc aaccagaggt atagatgtaa atgctaaggc agagatatat aatctaatgg
    13321 gagatttagt ggagagtggt gtaagtataa taatgatatc ttctgaaata ccagaattaa
    13381 tatcaatgag tgacagaata atggttatga gagaaggtca tataagtgga tttttagaag
    13441 gtgaagaaat ggttgaaaat aatgtattaa aattggcttt cggaggtaaa attaatgagt
    13501 tcaataacta agcataaaga agaaaaatct tctctattat tgacaaaatt aacaagtgca
    13561 tttagagacc aagggagtgc agctgtagga cttgtaataa tttttataat aatgagtgta
    13621 gcttcatcta actttttaac tttagataat ttaattaatg ttggaagaca aatatcaata
    13681 aatgcaatac ttgcagtagg tatgacattt gtaataatta caggaggaat agatttaagt
    13741 gtaggagcag taattgcttt agtaggtaca ttttgggcta caacagtagt gaattataat
    13801 gcacctatat gggtaggtat gatacttgca ttagcaatag ggacaatttt aggagtcata
    13861 aaaggtgcaa ttatttcaac acaaaaacta cctccattca ttgtaacttt agccatgtta
    13921 acgataataa gtggggcaag ctttgtattt acaggaggaa gacctatatc agtaaataca
    13981 gatgcattta agatgctcgg tagaggatat attggaccaa taccaatacc agttataatt
    14041 atgattatag ttgtaatagc aggacatttt ctattaaaaa gaactaattt tggacgtcat
    14101 gtacatgcag taggtggaaa tgaagaggcc gctagattat gtggagtaaa agtaaataaa
    14161 gttatagtaa aagtatacgc actagctgga ctgctaacag cattagctgg gataatacta
    14221 tcatcacgtt tggcatcagg ttcaccaact gttggagatg gagcagaatt ggatgctata
    14281 gcagccgttg tgcttggtgg tactaatatg atgggtggtt ctggttctat agtaggtaca
    14341 tgtataggtg tcggaataat aggaatatta ggaaatggat taaacttatt aagtgtatct
    14401 tcatataatc aaatgattat aaaaggtttg gtaatgttat ttgctatatg gataaataat
    14461 ataaaattaa aaaaatcagc taaatctaaa tagtaattaa attttagctt ataaactata
    14521 aaaattatta agtttttgta tatattttta tactttaatt tgcatacatc tttatacatt
    14581 gaatgggaat atgctaagtg aaaaagttta ctatggctta aatagatgag attagacttg
    14641 aaattttaaa tgtaaaaata aatcttagga ggaaatatga aaaaaattct cttagataca
    14701 ttaaatagta aaaaacaaga atacatagat tatttaaaag aacttgtaag tataaagact
    14761 gaagatgttg gtcatggaat actaggtgga tttgaaaaag aaggacagga atatattgaa
    14821 aaacttgcaa attacatagg ttttagtgta gatagacaag aaatgagcga agaattaatt
    14881 aaaaaagcaa aaaatatata taaagaagga aatctaggtc acaattatca agatagatat
    14941 aatttaattt gtaagtatag tgatgattta cctggtaaga caattgtatt taatggtcat
    15001 gtagacacta tgccaccagg tgatataagt aagtggaaat ataatccata tcgtgctaca
    15061 gaagataatg gaaaacttta tggacttgga actgctgata tgaaatctgg acttatagca
    15121 tcaatattag ctgtaaagct tataaaagat agtggtctaa atgtacctgg taatgtaaaa
    15181 ataatgtcag tagtagatga agaaggtggc ggaaatggta ccataaatgc agttatgaat
    15241 ggtattggtg gagattattg cataatttgt gaaccatcag aacaaaactt aatagttgca
    15301 catatgggat ttgtattctt tgaagttgag gttaaaggtg tgtctcttca ctgtggtagt
    15361 aagtgggagg gtgtaaatgc aattgagaag gctatgttgt tgcttcaaga tataaaagag
    15421 ttggaacata actggcttat gatatataaa catccactat taccttcacc tacaataaat
    15481 ttaggtgtaa taaatggtgg aacagcaggt tctactgtgc cagataagtg tgtatttaat
    15541 ttatgtgtac acttcttgcc aaatataatg agttatgaac aagttgtaaa tgatgtaaca
    15601 aatgtcataa tgacaagggc taatggagat ttatggctta aagataataa accaaatata
    15661 aacatatatc aatcagggtt aggttttgag atggacaagg attctgattt tgtagtgaat
    15721 gcacataaaa tactagaaga aactctaggg aaaaaattag agataaaagg ttcaacagct
    15781 ggcaatgatg cgagattaat gaaaaattta gctgaaatac caacacttat attagggcca
    15841 ggttcaatag aacaatgtca ttcaattgat gaatatgttg aaattaagga gtatttagat
    15901 agtatactta tgtatgcaag tataatatta aacttataaa agtaggagga atatataaat
    15961 gaaaaaagta ttaatagtag gggaatcttg ggtaaaaaat ataactcata taaaaggatt
    16021 tgatacgttt gttacaactc attatgaaga agctgtaaag tggttgaaag aagcaataga
    16081 atctggagga tatgagacag ttcatatgcc tgcacatgta gcagcagata gttttccgta
    16141 taaattagaa gagttaaatg agtatgactg tataatatta tctgatatag gttctaatac
    16201 gttcttatta tctaatagta cttttataga ttgcaatagt aatccagata gacttgaact
    16261 aatcaaagag tatgtaaata atggtggggc gttaatcatg gtaggtggat atatgtcatt
    16321 tacaggaata gatgcaaaag ctagatttgg agaaactgct atcaaagatg tattaccaat
    16381 aaccatgata gataaagatg atagagttga aaaaccagca ggaataattc cagaagttat
    16441 tgaatctgaa catccagtat taaaaggtat accaacagaa tggccaaagt ttttaggata
    16501 taacaaaaca gtagctagag ataattgtcc tgttttagca actattggag gagacccatt
    16561 tgtagctgtt ggcgagtttg gaaaaggaaa atctgctatc tttagttctg actgtgcacc
    16621 tcactggggt ccaaaagaat ttactgattg gaaatactat aataaattat gggttaatat
    16681 gcttgattgg ttaacatgct aaaaatttta taaaacttga aaacctctta cttgataaaa
    16741 tgaaacttac aagtcaagag gttttattgt ataaaatggt tgtatggtag aacatatttt
    16801 taaatcagtt aaaattagtc attttggttg ataatcgata agttattaga aacagggagg
    16861 tttatataat taatatggat aatttaaata aaaagttttt gatggaatat atagatgaga
    16921 tacagggaga attaagagat atatcagata ggatatggaa aaatccagaa cttcagtata
    16981 aagaatacta tgcttcaaat ttacaaaaag aatgtttaaa aaaacatggt tttagtatag
    17041 agggattaga aggtatggat acagcatttg tggctagtta tggagaaggt agaccagtta
    17101 tagcagtttt gggagaatat gatgctttag atggtttgtc tcaaaaagta tccactatta
    17161 aagaacctat tgtagatggt ggtgcaggtc atggatgtgg acataactta ctgggtacag
    17221 gttcaatagg agctgtaatt gcagtaaagg aattaatcaa actaaaaaag ctgaaaggga
    17281 ctataaaata ctatggatgt ccagcagagg aagatttatc tggaaaagta ttgatgataa
    17341 aaaaaggttt ttttgatgga attgattgtg cttttagttg gcatccattt gatataaata
    17401 ctcctataag aatcccaaca cttgctaatt actctgtgaa atttagatat aatgggatta
    17461 gtgctcatgc agcacaagct ccttataacg gaagaagtgc acttgatgca gtagaactta
    17521 tgaatatagg ttgtaattat ttgagagaac atatatttga taattgtaga gtacactatg
    17581 taactactaa tggtggaaaa atgccaaata tagttcctga ttttgcagaa gtgtggtatt
    17641 acataagagg agttaaaatg gagcatgtaa gagatgtatt tggtaggatt gttgatatag
    17701 caaaaggagc agcattaatg actggtacta ttatggaata tgacattata agtggagtat
    17761 atgactatat tccaaataca atattaacag atattctatc acaaaatatg aaattagtag
    17821 gtgtacaaaa ctataatgaa gatgactact attttgcaga taaattagct gagacagtgt
    17881 ctatagataa aagaagtagt gtttctagtg tcttaagtgg aaataaggat attactaaga
    17941 tgaatttaca tgatgaggtt acagatgata catttactca taataactgt atatcattat
    18001 cattggatat tggagatgtt agctacataa ttcctacagc acagtgttct tgttcagttt
    18061 ggcctattgg tatttctgcc catacatggc aatcttgtgc cagtgcaggt tctgatatgg
    18121 gatttaaggc aatgttattg gcatctaaat ctatatcatg ttcaataaat gatgtaatgc
    18181 ttgatgaatc ggttataaat aaagcaaaaa aagaattgaa ggatactgta ggtagtttta
    18241 aatatatacc aattatttaa aacttaaatt gatataagca caactaactt gtatgagtta
    18301 atataagtat ataatttaat attattttta acccaacctt ctaattattt taaatttaag
    18361 atacaatgat tagaaggaat tttttaagtt tcttagaata ctgtaaatta tataatcttg
    18421 ataaaaagtg ttatactata tataatctaa ataaaaaata gtacaaaaag gagtatttat
    18481 gtttggatat gttaaaataa acaaaatgga tttaacattt agagaatatg attattacaa
    18541 agcttactat tgtggactat gtaaatactt aaaaagaaat catggagaaa tctctaggtt
    18601 ttctttgaat tatgatataa catttttaat tgttttatta acagcagtat ataacccaga
    18661 gtctataagt acagaggaag tgtgtatagt aaatccattt aaaaagaaaa aggtaattac
    18721 aaatgatatt acagaatatg cagcaagtat gaatattctt ttaacgtatt ataaattgga
    18781 agataattta atggatgata aacgcataaa agataaattg gcatattata tatataaaaa
    18841 caaattaaaa ttagcatatg aaaagtatcc tgaaaaagca gagtatataa aacaacaact
    18901 aaatgaatta aataagttag aaaaagataa aaatataaat atagatgaag tatctagtat
    18961 atttggaaat ataatgggtg aagtatttgt ctataaaaaa gatgaaaatg agagaaactt
    19021 aagaatgata ggttttaata taggtaagta tatatatcta ctagatgcct atgaagattt
    19081 agatgaagat tttaagaaag gaagatataa tccatttata gagtatattg ataaaaataa
    19141 tgagttaaaa gaaaaagtaa aaaaaataat agtaacatca ttaggatttt tagctagggg
    19201 aattgataat ctaaatctaa ataaaaatgt tggaataata gaaaatataa tttattctgg
    19261 tgtttattta agatatatta atatattaga aagtagaggt ggaaagaatg tacagtaata
    19321 cttataataa tgaaaatttt atgagagcaa gatcattcat agaaaatagt gaatttaaaa
    19381 aagcatatga ttttttaaaa actttgactg acaaatgtgc agagtggtat tatttaactg
    19441 gtttttctgc aatgaacata ggatattatg aagaaggtga agacttctta aaaagagcaa
    19501 aatttatgga gcctgaaaat agtgaatata gtgatgcact tagaagttat acacaatata
    19561 gaaatgatta tagcaatagg gctgacaatt ataatagaag aagacgtaat gatttagatg
    19621 gatgttgttg ctgttgctgt gatgattgct gttgttgtct aggtgacgat tgttgtgaaa
    19681 attgtgctaa gctttggtgt ttagattcat gttgtgaatg ttttggtgga gatttaataa
    19741 cttgttgtta ggatgataaa tatgagtata aaagttgctt atggaggagt tttattagca
    19801 ttaaatgtga tattgttgac tcttacaaat attattcctg taaatacatt gtttattatg
    19861 gggttagcat cacttttagt atcaattgta ataatggaat ggggctttaa gagtggaatt
    19921 gctttttata taggttctat agttttagga tttatagtga tggcaagtaa gtctcaatgg
    19981 attgtatatt cacttacctt tggaatatat ggtattgtaa aatatcttat agaaaaagat
    20041 aggtctatat atattgagta ttttatgaaa ttagtatttg caaatataat gatacttata
    20101 ttgtattttt tattaagaac aatagtttat attccaataa acatatttat tataggttca
    20161 tttgagatag cctttatagt atatgactat gtttacagtt cttttatagg ttattacaat
    20221 aatagattaa gaaagatgct atttaaaaaa taatagttga tttttatatt taattttaat
    20281 gaaattgtag tttagataag tgtaaatgat atatctgaat atacattaaa gcataaagct
    20341 aaatttaata tattcttagt gcaacatata aaagctttga tttttagtca aagcttttat
    20401 atgttagata taaatattag atataatata agtttttaaa atagatagta taaattaaat
    20461 atccactata tttacatctg tagatagaga ataaataata tcttttcttt ctactattat
    20521 ctcaacattt ttagaaattt cctcatcaag tgatatttga gataaaagtt cttttgttgg
    20581 atttattgct attggatttc caactctttt tagcatattt atatcaccat tagtatctcc
    20641 ataggcatac gagtttgata aatctaaatc atactttaca acaaaatcgt ttatagcatt
    20701 attcttactt atagaatccc acattggaat aactgtacct gtaaatatat tgttttcaaa
    20761 gacataatca cttcctagaa aatcggttac attatatttt ttggccattt tttcaacaag
    20821 aaatccaggg ctaccagata taaatataac tatgtgtcct tgatttagat gccactcaat
    20881 ccttgaacgt gtgtatttat aaactctatc tgcttttaat ttaattactt ggtcacttgt
    20941 aaagttgata caggttttat ctaatccttt tagtgaatca acataaaggt cacatatttc
    21001 taatagataa tcatcataat taccttgtct tttatcccaa tccataaaag tgtctctagc
    21061 atgtttatac caattttttt ggtcaattat atcgtattta attaattttt taaaatgttc
    21121 aaccataaga gagtctctat aaagagtacc atctatatca aaaaaagctg ctatattttt
    21181 cataagacca cctcaattaa tcatttcctt atattatatt ataaattgta tctaagttgt
    21241 taaaatatat gtataataat ttatatatta aaaaacaagt attttagagt ttaaaggatg
    21301 tgactatatg aattttaatt ttgcaaaggc tacaaattct agacttatgg gcagtttagg
    21361 tcttataata aattggatag atgatgaaaa caatcacttt tgtcaatatt ttttattaga
    21421 tgcagaggga ttaggattag cggattatgt gagtttaaat aacccaacac aagaagaagc
    21481 ttatatggaa gaagaaagat tgatgggagg atttggttca gatagagttg aattaacgaa
    21541 ggatgaatct ttatttttag tatcttattt tggtaataag aatctttatt atgataagct
    21601 attgccagga gataaatgtg agtatattga tattataaaa aactataaaa cagatttaac
    21661 tatagaaaaa ttatacaata aaatatgtaa aagagttgac gaggaagttg aatttataaa
    21721 ctatatgacc atgagattta tagcatggga tagagaaagt ttaaagtact tttctggaag
    21781 tgacgagatt gcaaatatgc acattactaa tataaatgga acattactta aaaacgtggt
    21841 aagtgataaa ggtcaaggca gatatataag tgaagcttta tatgaagata atgatggata
    21901 ttatatatgt aaaattgctt tttgcataag taagtgttat gaaactggtt ttagaattaa
    21961 ttctctatta gtgacagata aagaacctat gtatgatttt gaggtatttg atgagatttc
    22021 taaaagtgaa tttgtaagtg tttacagtgt aaattcacct gaagaatttg caggagtatt
    22081 ttatagagaa aatccatttc tgttaaaaag taatatgaat gaaggtatat tctttactag
    22141 atttaatttt aataatgacc atgtaaaaga aaatgtatat ataataaata atgatatgaa
    22201 agctatatat tacttaatgg gaaataagtt ttttattggt acttataacg aaaatgattg
    22261 caattatatc aatgaaataa gtcaatctaa ttatagcgac tatattaaat ttgaagagaa
    22321 atttttcttt gagcaaaatg cattatatga ttttgcagaa tcaggttcat tagattttga
    22381 tgattttttg gaataataaa tttagacatt atttaagcga gattaactga atttaatctc
    22441 gcttaaattt atttctataa tattggggga atattatgag gaatacattt attattgtgg
    22501 tcaattatta aaattttata cagtttatta taaaaaattt atacttttct ttatgttgtt
    22561 tgccaatatt agtttcaaat acgagtacca tactattctg aatcaccaac acaagagagc
    22621 atttttaaat gaaaaagtca gataaaatta aattttatct gactttttct atgtttatct
    22681 tattagatta tgttaatatc tgttgaccga ataagcgcat attcagtcaa ctttctatac
    22741 ctataataat attgggggaa tattatgagg aatacattta ttattatggt caattattaa
    22801 tgttttatac aacttactta aaaaaatata tattacattt cttcctcatc aaattcctca
    22861 atattagtag cttgtggtat accttgtaca gacatattac tagaaccata aggagtagga
    22921 tatatattag gaggcatagt actaggcata actacaggca taccttgcat tgtattatga
    22981 catataactc ctggtatcat cataagtaca ttaggaggca tattttgatt acatgagaag
    23041 ttaggaatac ccatagtatt gttcatatta taccccatat tactgttcat gttattaggc
    23101 atacctgtat taccatacat attgttattc atattgccag acatattgtt aggcataccc
    23161 atattactat tcatattatt agacatattg ttaggcatac ccatattact attcatgtta
    23221 ttaggaacat tgttaggcat gcccatgtta ctattcatat tattaggcat attgttaggc
    23281 atacccatat tactattcat gttattagac atattgttag gcatacccat attactattc
    23341 atattgttag acatattatt aggcataccc gtattattat tcatgttatt aggcatatta
    23401 tttgtagcag atgtattgta attcatattt ccggatgtat tatttgtgtt aggcaagttg
    23461 tttggagaat tactactttt aggataatga tttacattat taggatatag gttatttatg
    23521 ttctggttat taggtatttt tgtataacca ttagaaattt gagggtcatt tctcaattca
    23581 tcttggggaa tttcttcatt agtaatataa tctgcatagt tcgctgggtc taagtaaggc
    23641 atgtaactag tatctaaatc cttttttttc ttgttactca tattaaactt gcacctccta
    23701 gaaaactata aaaaagttta caaaaactta ttctaataat atatatatta aaaaagttta
    23761 taatatgtgc attctattta tattaaatta ataaaaatta ttgttgcaaa tttagaaatg
    23821 ataacatata atgaacatat gaacagttat tcatatatta aaataatgga ggattaaaaa
    23881 tgagagaaga gataaatgat tgtaattgta atatagtaca tgaagaaata gtaacagagg
    23941 ctaaatcaac tatgccagat gaagaaatgt tatatgattt agcagaatta tttaaagtat
    24001 ttggggatac tactagagta aagatattat atgcattatt tgcaaatgaa atgtgtgtat
    24061 gtgatatagc gagtttatta aatatgactc attctgcaat atctcatcaa cttagagtat
    24121 taaagcaggc tagattagta aagtttagaa gagaaggaaa aacagtgtat tactcattag
    24181 atgatagtca tataagtcag atatttgatt gtggattaaa tcatattaga gagacttata
    24241 aatgataaat gagaggagtg aatatatatg gaagcaaata attcaattaa aaaagaattt
    24301 atactaggag gattaaattg tgctcactgt gcagaggaga ttaataataa agtttctaaa
    24361 ctacaagaag ttaaatcttc caatttaaat tttataaata aaaaacttac agtaaatata
    24421 aaggaaagtt ttaatgagga tactactata gaaaagataa tagatataat agattcaaca
    24481 gagccaggtc ttgatataca aataagttct aaagaaaatg cagctagtaa aacatcaatt
    24541 aaaaaagagc ttatattagg aggattaaac tgtgctcatt gtgcagaaga gattaataac
    24601 aaagtttcta aattaaaaga agttgaatct tctaatttaa actttgtaaa taaaaaactt
    24661 acagtaaata taagtaataa ctttgaagag gatgatgtta taaataaaat aaaagaaata
    24721 ataaattcaa cagagccagg gcttgatata caagtagggt ctactgacaa agtaaaaggg
    24781 agaactactg aaaaatcagg agctgtaaat gatacaaata agaaagaatt aattccactt
    24841 ataattggag cacttgtata tatatttggt atatatcaaa cagctacagg ttatgaaagt
    24901 cagtttagca atatagtatt tatagttgcc tatgtaatag taggtggtga tgtgctttta
    24961 agagcaataa gaaatatatc aaaaggaaga gtatttgatg agaacttttt gatggctcta
    25021 gcaacagtag gagcattagc aataggggag ttatcagaag cagtaggggt tatgcttttc
    25081 tataaagtag gagagtattt acaaggtgtt gcagttggta aatccagaaa gtctataact
    25141 tcacttatgc aaataagacc agactatgca aatctaaaag ttaattctga agttaaggtg
    25201 gtgtcaccag aagaggtaaa tgtaggtgat ataatagtag taaaacctgg tgaaaaagta
    25261 ccattagatg gtgtagtagt agatggagtt tctatgttag atacttctgc actcacagga
    25321 gagtcagtgc tgagagaagt tgaaaaagga gatgaaatct tatcaggtgt tataaataaa
    25381 aatgctttat tgagtattga agttacaaag agttttggag aatcaacagt ttctaagatt
    25441 cttgaccttg ttgaaaattc tagcattaaa aaatcaaaga cagaaaactt tatatctaag
    25501 ttttcaagat attatactcc aatagtagta atagctgctt tattaatagc atttgtgcca
    25561 ccacttgtaa tctcaggtga ggtatttagt gattggttat atagaggatt gatattctta
    25621 gtcgtttctt gcccttgtgc attagtttta tcaataccac ttagtttctt tagtggaatt
    25681 gggtttgcat ctaaaaatgg tatccttatt aaaggaagta actatttaga agctttaaga
    25741 agtgtagata cagtagtatt tgataaaaca ggaacactta ctaaaggtgt gttcaatgta
    25801 actaagttaa atcctgaagg tatatcagaa gaagaattat tagaatatgc agccattgcg
    25861 gaggtaaatt caaatcatcc aatagcaaag tccatattaa gttactataa taaaaaaatt
    25921 gatttagata caatagacag ttatgaggaa atagcagctt atggaattag agtaaagcat
    25981 aatggcaatt ttatattagc aggtaatgag aaacttatga aaaaagaaaa tatatcttat
    26041 tcatcagcta aagaagtagg cacagtagtc tatattgctg ttgataaagt atatagaggt
    26101 tatatagtta tctctgatga agtaaaagaa gatagtaaaa atgccataag aagcttaaaa
    26161 gaaatagggg taaaagaagt tgtaatgtta acgggagata atgagaaagt agcaaaaaat
    26221 attgctcaag aattagaatt ggatacagtt tactcaaatt tacttcctaa tgaaaaggta
    26281 gatagattag aagatttata tgaaggaaga actgaaaaag agaaaatagc gtttgtaggt
    26341 gatggaataa atgatgctcc agtattagct cgtgctgatg ttggtatagc tatgggaggc
    26401 ttaggttcag atgctgctat tgaagctgca gatgtagtgc ttatgacaga tgagcctagc
    26461 aagatatcta aagcaattga aatagcaaac aagactaata agatagtgtg gcaaaacata
    26521 atatttgctc taggagtaaa aattatagtt atgatactag gtgctggagg agtagctact
    26581 atgtgggaag ctatatttgc tgatgtaggt gtggcactta tagcagtagt aaatgctatg
    26641 agagctatga gataagggat aaatgtaaat ccatactatt taaaaaactt ataattatat
    26701 attgaaatat gtaataatga aaggtatcaa taagtttctt ttaactttat tggtaccttt
    26761 ttattggagc actttgcata tataaattta tattcattat ccattatgtt tatttaatgt
    26821 atttatttag tgtagagctt ttatattgta attttaaaat ttagacatag aaggtttatt
    26881 aataagttta tattaagttt aaattagatt cataaaaatt ataatactta tgattgtata
    26941 tatattatat taatagttgt aatttttaca acaaaatgtg tgtgttaaaa tactctaaaa
    27001 caacagtata actgccattc aataaattat gtaatataag aaagtaaata tttttaaaaa
    27061 ataatttaaa aaagtattga cgaattattt ttaaggtgat atagt
//
LOCUS       DAEORM030000051        26778 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.051, whole genome shotgun sequence.
ACCESSION   DAEORM030000051 DAEORM030000000
VERSION     DAEORM030000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 26778)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26778)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 26778)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26778
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.051"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            complement(150..563)
                     /locus_tag="KRH23_002824"
     CDS             complement(150..563)
                     /locus_tag="KRH23_002824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009298860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich VLP domain-containing protein"
                     /protein_id="HHS5226102.1"
                     /translation="MKNNPYKDLPPLECRPDGSLYRMTPAQRKRASALIRRECCCCED
                     GNCIALDDGDTCTCPQTISFSVCCKWFRWAVLPLDGTLEAEIFRDKDLKRCAVCGGVF
                     VPKSNRAKYCPGCAARVHRRQKTESERKRRSAVDS"
     gene            944..1489
                     /locus_tag="KRH23_002825"
     CDS             944..1489
                     /locus_tag="KRH23_002825"
                     /inference="COORDINATES: protein motif:HMM:NF019544.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HHS5226103.1"
                     /translation="MDQGRIIVITGSPGTGKTTTASTVAKESDLEKSVHMHTDDFYHY
                     LSKGAIPPYLPESNEQNLIVIEAFLEAAKRYARGGYDVIVDGIVGPWFLEPWLNIVQE
                     HYEVHYIVLRASKEETMKRAIKRSKLDRETNIELVETMWEQFSNLGIYESNVIDTTTH
                     SVKDTVSAVKEKIVRGTALLL"
     gene            1527..2327
                     /locus_tag="KRH23_002826"
     CDS             1527..2327
                     /locus_tag="KRH23_002826"
                     /inference="COORDINATES: protein motif:HMM:NF024252.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHS5226104.1"
                     /translation="MELSIQERLKDLRVERGLTLEQLAEETHLSKSALGSYEGDKFKD
                     ISHYALIQLAKFYEVSVDYLLCRSETKNHPNADLADLRLSDDMIEFLKSRLVDNALLC
                     ELATHPDFPRLMADLEIYVNGIAAKQVQGANAIVDAVSATIMKQHNPGLTDPQLRQLI
                     AAHIDDDSFCRHVIQQDINKIALDLRKAHKDDFFSVPEDNPLEDFLQTAEEAASPNSD
                     PEQAAMAFICKRLKLNYGKLSEEEKKWLKRIAQKSDLLKNPNPQRGRK"
     gene            2338..2805
                     /locus_tag="KRH23_002827"
     CDS             2338..2805
                     /locus_tag="KRH23_002827"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002599264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HHS5226105.1"
                     /translation="MQKGKMRFIEVETKNRTADFINRLLTVWESSVRATHLFLSDSEI
                     KKIKEYVPQALAGIAHLMIAEDDRGCPGAFMGIKDGTLEMLFISPEERGKGLGKRLLQ
                     YGIKTYAVERVAVNEQNPQAKGFYEHMGFQVYKRTDLDEQGNPYPLLYMSLNI"
     gene            2971..4872
                     /locus_tag="KRH23_002828"
     CDS             2971..4872
                     /locus_tag="KRH23_002828"
                     /EC_number="5.6.2.-"
                     /inference="COORDINATES: protein motif:HMM:NF013311.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase"
                     /protein_id="HHS5226106.1"
                     /translation="MATDKKKQFKIVAELLKQANTIIVATDSDREGENIAWSIIHKAN
                     AFSKDKTYKRLWINSLEKDVIRSGFQNLQPGMNYYPFYQEAQTRQIADWLIGMNASPL
                     YTLNLQQKGVQGTFSLGRVQTPTLYLIFQRQEAIENFRKEPFFEVEASIKVNQGSFKG
                     VISPTQRFKTQEELLAFVSSEQAKIGNQEGIIADVQTKEKKTNSPSLFSLSSLQSKVN
                     QLYKATASQTLKAMQGLYEAKLLSYPRTDTPFITENEFAYLKANFGKYSGFLGLDLEM
                     VQTEPRKRYVDGSKVQEHHAIIPTKQVPTESALAKMDDLQRKIYALVVKTTVAMFLPD
                     YLYEETKIQTKVADLLFQSIGKTPKQEGWKILFKQQTKEEEEDVQTLPLVIIGEHAEV
                     DVKSAEKETQPPKAFTEGTLLTAMKTANKTVDDEEAIKILQEVEGIGTEATRASIIEA
                     LKQKEYIQVIKNKLVVTEKGKLLCQAVESQHLLTSAEMTAKWETYLKKIGKREGNQEN
                     FITNIKKFIVHLLEAVPNDIEKLNFSDYQEQKEKEAEKSIVGKCPKCGNNIVLKKSFY
                     GCSNYPECKFTLAEHFRKKKLTKTNVKELLEGKETLVKGIKTKDRKSYNAVVKIGEKG
                     YIDFISFSK"
     gene            4998..5231
                     /locus_tag="KRH23_002829"
     CDS             4998..5231
                     /locus_tag="KRH23_002829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000502600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226107.1"
                     /translation="MGNLGAQKEKRNDTPISAKKDIMGDKTVRVRADLHHIIKIETAK
                     NGGNVKEVMEIRLRSKLKSVLIVQYLKILYNRN"
     gene            5278..6015
                     /gene="erm(B)"
                     /locus_tag="KRH23_002830"
     CDS             5278..6015
                     /gene="erm(B)"
                     /locus_tag="KRH23_002830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011100845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HHS5226108.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGSIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            6020..6151
                     /locus_tag="KRH23_002831"
     CDS             6020..6151
                     /locus_tag="KRH23_002831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226109.1"
                     /translation="MSRFCKFGKLHVTKGNVDKLLGILLTASKELKRSLAPTGNLYR"
     gene            6161..6445
                     /locus_tag="KRH23_002832"
     CDS             6161..6445
                     /locus_tag="KRH23_002832"
                     /inference="COORDINATES: protein motif:HMM:NF024738.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="topoisomerase DNA-binding C4 zinc finger
                     domain-containing protein"
                     /protein_id="HHS5226110.1"
                     /translation="MPTKRSGPLVGKCPKCGNNIVLKKSFYGCSNYPECTFTLAEHFR
                     KKKLTKTNVKELLEGKETLVKGIKTKDRKSYNAVVKIGEKGYIDFISFSK"
     gene            6590..7444
                     /locus_tag="KRH23_002833"
     CDS             6590..7444
                     /locus_tag="KRH23_002833"
                     /inference="COORDINATES: protein motif:HMM:NF013793.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HHS5226111.1"
                     /translation="MEKEELKILEELRRILNSKNEAIVILNNYFKGGVGKSKLSTMFA
                     YLTDKFNLKVLMIDKDLQATLTKDLAKTFKVELPRVNFYEGLKNGNLASSIVHLTDNL
                     DLIPGTFDLMLLPKLTRSWTFENESRLLATLLAPLKSDYDLIIIDTVPTPSVYTNNAI
                     VASDYVMIPLQAEEESTNNIQNYISYLIDLQEQFNPGLDMIGFVPYLVDTDSTTIKSN
                     LEELYKQHKEDNLVFQNIIKRSNKVSTWSKNGITEHKGYDKKVLSMYENVFFEMLERI
                     IQLENEKE"
     gene            7542..7751
                     /locus_tag="KRH23_002834"
     CDS             7542..7751
                     /locus_tag="KRH23_002834"
                     /inference="COORDINATES: protein motif:HMM:NF019384.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226112.1"
                     /translation="MGNLGAQKAKRNDTPISAKKDIMGDKTVRVRADLHHIIKIETAK
                     NGGNVKEVMDKALEEYIRKYLPDKL"
     gene            7768..8040
                     /locus_tag="KRH23_002835"
     CDS             7768..8040
                     /locus_tag="KRH23_002835"
                     /inference="COORDINATES: protein motif:HMM:NF020567.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HHS5226113.1"
                     /translation="MAVTYEKTFEIEIINELSASVYNRVLNYVLNHELNKNDSQLLEV
                     NLLNQLKLAKRVNLFDYSLEELQAVHEYWRSMNRYSKQVLNKEKVA"
     gene            8042..8797
                     /locus_tag="KRH23_002836"
                     /pseudo
     CDS             8042..8797
                     /locus_tag="KRH23_002836"
                     /inference="COORDINATES: protein motif:HMM:NF018154.6"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
     gene            complement(9514..9648)
                     /locus_tag="KRH23_002837"
     CDS             complement(9514..9648)
                     /locus_tag="KRH23_002837"
                     /inference="COORDINATES: protein motif:HMM:NF013540.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HHS5226114.1"
                     /translation="MQIKIGKVIQCLRKERNLTQEQLAKFIGVSTPAVSKWESGVSHN
                     "
     gene            complement(10113..11048)
                     /locus_tag="KRH23_002838"
     CDS             complement(10113..11048)
                     /locus_tag="KRH23_002838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysophospholipase"
                     /protein_id="HHS5226115.1"
                     /translation="MKCTNFTFKGEEGLDIYTYKWEDENIKKPKAVIQIAHGMAETAQ
                     RYETFAKVLTKNGYIVYINDHRGHGKTAKIIENVGHLAEKEGFRCLVEDMYTLTNIIK
                     KENEDLPIYLFGHSMGSFASQRYIMDYSNNLSGLILCGSNGKQGIILNLAHLIINHEI
                     KKYGRRFKSNKINNLIFGGEIIRRNEKTKFDWLSRDKEQVEKYINDPFCGVVCSCGFF
                     YDLVQGLKEIEDKENLKKVPLDIPIYIISGDKDPIGKNGKGVLRLRDRYIKLGVKDVT
                     CKLYKDGRHELLNEINREEVFEDIICWLNNKIEIL"
     gene            11336..11902
                     /locus_tag="KRH23_002839"
     CDS             11336..11902
                     /locus_tag="KRH23_002839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HHS5226116.1"
                     /translation="MDYSNELKELFLMNQTYATLFTLTNKIQIEGDKYFGILTSRQYM
                     TILSILHLPEEETTLNNIARKMGTSKQNINRLVANLEKNGYVDVIPSPHDKRAINVKV
                     TDLGKKVMVTCSRTGINFMADVFHEFTKDELETLWSLLKKMYRFNGEEQDGFEEDANF
                     MEYEEIDKIKSEALEEFAKRRNRVNKND"
     gene            complement(12093..14129)
                     /locus_tag="KRH23_002840"
     CDS             complement(12093..14129)
                     /locus_tag="KRH23_002840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin domain-containing protein"
                     /protein_id="HHS5226117.1"
                     /translation="MDSNRKPNNLINEKSPYLLQHAYNPINWYSWNDEAFKKAKEEDK
                     PIFLSVGYSTCHWCHVMEKESFEDEEVAEIMNRNFVAIKVDKEERPDVDSVYMTVCQA
                     MTGSGGWPMTIIMTPDKKPFFAGTYFPKYSRYNRPGVIDLLENVSEKWNTSRDILIKS
                     GDEIIEALKDDFGVKNTEGDLSKEMLSSSVRVFKAIYDEKYGGFGNAPKFPSPQNLMF
                     LMKYYSIEKDKDVLKMVEKTLDGMYRGGLFDHIGFGFSRYSTDKKWLAPHFEKMLYDN
                     AMLTIAFLDAYKITKKELYKEIAIKTIDYVVREMKDKEGGFYSAQDADSEGEEGKFYT
                     FNPLEIIEVLGEEDGTFFNNYFDITSSGNFEGKSIPNLIKNKEYERHNEKIADLSKKV
                     FEYRKERTSLHKDDKILTSWNALMIVALTKAYSTLKNDIYLEYSNKCLNFINNNLVNE
                     SGRLLARYRDGSSDYLAYLDDYAFLIWAYIELYESTFNMKYLEKALNLNESCINLFWD
                     YEKSGFYIYGKDSENLIARPKDLYDGAIPSGNSVQLYNLIRLAKITGDNRLEEMSYKQ
                     LKLYVDNVKGSPTGYSFYMLSLMFELYSTKEIICIFKEDSDLIAFKELISENFIPNAT
                     FLAKKYNEENTIIGFLNNYILKDDKTSYYVCQSNSCSQPINDLQKLKDMILGVE"
     gene            complement(14303..14980)
                     /locus_tag="KRH23_002841"
     CDS             complement(14303..14980)
                     /locus_tag="KRH23_002841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HHS5226118.1"
                     /translation="MFKHDKALLKEVKVERPNPQYAVLMQEQLGGANGELKAAMQYLS
                     QSFRIKDPQIKDLFLDIAAEELSHMEMVAQTINLLNGHDVDYNSVNTGEIETHVLTGL
                     SPVLINSSGAPWTANYVTVTGDLVADLLSNIASEQRAKVVYEYLYRQIDDKYVKETID
                     FLLNREEAHNALFRDALNKVKDTGSNRDFGVTEDSKLYFDLSTPGPNHDTKIDINPPS
                     FEKPLKK"
     gene            15323..15451
                     /locus_tag="KRH23_002842"
     CDS             15323..15451
                     /locus_tag="KRH23_002842"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226119.1"
                     /translation="MSRIERRKKDRESKLAKVKTALSILPILINLIDKLIKLLKDL"
     gene            15697..15873
                     /locus_tag="KRH23_002843"
     CDS             15697..15873
                     /locus_tag="KRH23_002843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226120.1"
                     /translation="MEQKESKIVYSKGGSGTYSAKISLPLSQLEKMGFTREKRKAVVI
                     FKEDEIIIKKSDEE"
     gene            16034..16162
                     /locus_tag="KRH23_002844"
     CDS             16034..16162
                     /locus_tag="KRH23_002844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226121.1"
                     /translation="MGRLERRKNKRENKFNKIKNAFSFTLVLINLVLAILRLIKEL"
     gene            16391..16576
                     /locus_tag="KRH23_002845"
     CDS             16391..16576
                     /locus_tag="KRH23_002845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB/MazE/SpoVT family DNA-binding
                     domain-containing protein"
                     /protein_id="HHS5226122.1"
                     /translation="MILLEQRKLRIGFNKSGKGSFTPRLILPMSWIKEMNISPDERDV
                     LVTFEDGKIIIEKTENE"
     gene            complement(16618..18909)
                     /locus_tag="KRH23_002846"
     CDS             complement(16618..18909)
                     /locus_tag="KRH23_002846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HHS5226123.1"
                     /translation="MKNLSKKAVILSLSLVVVSPLVHKINAQDIEKNREVRYETRKAN
                     NLENMTMEEAFPDENFRKVICDKLSILDDGNPIGISQKAIIESTKGLTLGSKSIKNLS
                     GINYFIGLENFSCRGNNLTSLDLSSNINLKELYCNENQLTSLDLSNNRELTTLHCGEN
                     NLTDLVIENSKLDELNCRKNNLKSLDITKATNLTTLLCFENELTSLNLSKNQKLKILK
                     CDYNNLNDLDISTNLELQDLNCSFNQLENINLDNNKELVKLICHNNKLQNLNLKNHEK
                     LVKLYCNQEQLSTLNVENCINLEDLTCSRSNLKNLDISSNKNLKYLECVANKLTNLNI
                     ENNIELLELYCYDNEIKALDISKNIDLENLTCYKNKLDSLNTSKNKNLKYLYCSQNEL
                     TSLDVTKNTELVRLYCGENRLTSLDVSKNTKLKELDWSNQKKSTSTGGSSGSGGGSSS
                     TNEESSEPTSTPSKEKLTGVDRNETSVKISQKGWNKADNIVLINDSSISDALSATPFA
                     KSKDAPILLTKNNNLNKLTEKEINRLEAKNVYIVGGLKSVDEKVVSDLKKKGLNVIRI
                     SGNDRYETSIKLAKELDKNSNLSKVVVVNGEKGLADAVSMGAISAKEEMPILLTNQND
                     DMKDIKDLIANKNISKSYVIGGESLFNNKEVNNTLPSVTKIAGSDRTETNSKVISHFY
                     SKDTLNDLYVAKNGMNKQDDLVDALSVGVLAGKTESPVVLVGNGLDNSQKELIKNKKF
                     KNITQIGGNGNEKAFNEVENLVK"
     gene            complement(19066..19878)
                     /locus_tag="KRH23_002847"
     CDS             complement(19066..19878)
                     /locus_tag="KRH23_002847"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008745 - N-acetylmuramoyl-L-alanine
                     amidase activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HHS5226124.1"
                     /translation="MKICITVGHSILKSGACTSADGVVNEYQYNKSLAPVLADTFRKE
                     GHKADVIICPEKQFKTKAEEKTYKIPRVNSGGYDLLIELHLNASDGQGKGSEVLYYSN
                     KGLEYATRICNKLGTVFRNRRAKLDKGLYILNSSNPTAVLIESFFCDNKEDYEKAKKL
                     GHEGIAKLIVEGVLNKNINNEGVKQMYKHTIVYDGEVDKISATVVGWGYNDGKILICD
                     IKDYVPGQTQNLYVIGGAACEKIGSMTKEKFTMIKGNDRFDTLYKALDFINR"
     gene            complement(19957..20820)
                     /locus_tag="KRH23_002848"
     CDS             complement(19957..20820)
                     /locus_tag="KRH23_002848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Abi family protein"
                     /protein_id="HHS5226125.1"
                     /translation="MVEVKEEKTFDEQIDILKSRGLIINDKEDAKFVLSNVNYYRFTA
                     YLLSFKNDDGSYKEGTTFEEVYDIYRFNKEFRILLTDLLGSIEIAFRTYIAYTLAIKH
                     GACGYLERESFKDEKFYINFLTALEREKNNNSDKLFIIHHKEKYEGKLPIWVATEIMT
                     FGMLSKLYSNMLPEDTRYIKNNLCRVNTLLVKSWLQSLTQVRNQCAHYGRIYNNNFRI
                     ITIKNEYKKYNLDNKKIFSYILAMKHLTMDKLIWNSFFIKLQKLINDYNNSIDLKLIG
                     FPNNWIEILAK"
     gene            complement(21081..21338)
                     /locus_tag="KRH23_002849"
     CDS             complement(21081..21338)
                     /locus_tag="KRH23_002849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HHS5226126.1"
                     /translation="MDNLISFIPEQLLILVAALSIIGKGCKKYKQLDNKYIPVVLLIL
                     GIGFSIWMLGLNPVAVLQGVICWGVAIGINQTYKQLKDGEK"
     gene            complement(21358..21588)
                     /locus_tag="KRH23_002850"
     CDS             complement(21358..21588)
                     /locus_tag="KRH23_002850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin XhlA family protein"
                     /protein_id="HHS5226127.1"
                     /translation="MNEELFEADLKRHETRINKHGEEIDELKIANIESKAELKALCEN
                     LNSLTSMLKWLIGTMITTLIGFFIFAIQRGIF"
     gene            complement(21626..21808)
                     /locus_tag="KRH23_002851"
     CDS             complement(21626..21808)
                     /locus_tag="KRH23_002851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226128.1"
                     /translation="MNINNVVVRILAERILSGGLNPLKNREFQLDDVTNTEYRKAVED
                     YIIKQSGVVEGAEPTV"
     gene            complement(21808..22113)
                     /locus_tag="KRH23_002852"
     CDS             complement(21808..22113)
                     /locus_tag="KRH23_002852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226129.1"
                     /translation="MTEYIEVGRRIFFDEEGEIIFYEGQSKGNVPERKNIKKIEYIDL
                     EYDYVDYDKYKIIGIDIRTKQPILEEIPVYMSEEEKRIQELENQILIAENEKVGGIL"
     gene            complement(22137..22742)
                     /locus_tag="KRH23_002853"
     CDS             complement(22137..22742)
                     /locus_tag="KRH23_002853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226130.1"
                     /translation="MIEKLNENASLSDLITTFENVKDELQIGKNNIASTLGSPFVGTD
                     KLSVTKTKIQTLKNTLAISLSMKNISAQSTETLHSLISKVVGIENIFIAQGECTQVGE
                     KTFQLYQVDNNTPKTCSANAISFNLAFTPKFIIVYRNAYNIDLCSFVFYSSFRNIITA
                     VPQPSNFGEMYTPNTFDCVVGHTCILPVKDYKIPHFFYAIA"
     gene            complement(22936..23139)
                     /locus_tag="KRH23_002854"
     CDS             complement(22936..23139)
                     /locus_tag="KRH23_002854"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226131.1"
                     /translation="MKKQFYYDSLEEKEKIINESNNLYVIELSETLKGKYIILSDNPI
                     YEKLSYEELENELLTNELKGEIL"
     gene            complement(23150..23782)
                     /locus_tag="KRH23_002855"
     CDS             complement(23150..23782)
                     /locus_tag="KRH23_002855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226132.1"
                     /translation="MTEKLTDNASLRELMTTLQGVQTDFQNSKSNITTVLGSPFLNTD
                     KLDITKTKIETLKSVLVNNLIYKGVSASTQSSFTDLINAINFIVQSILIVKCKDTERV
                     EEVNNPYIIYNDKPNIKGCLRIKGTLMVYKNWATFASSRLEIIYGEKKEYIYLSCDAT
                     ASGRSMNFEKDIIVNNDTQLKIQVLLTDVGTGNSSTAKAYTSVSDVTLLR"
     gene            complement(23796..23987)
                     /locus_tag="KRH23_002856"
     CDS             complement(23796..23987)
                     /locus_tag="KRH23_002856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226133.1"
                     /translation="MTFKELVNKVRNLVLEAKNVTIEDTENLFESDNVEVALKELATE
                     VNGQRAKGITIANDLIDMI"
     gene            complement(24021..24191)
                     /locus_tag="KRH23_002857"
     CDS             complement(24021..24191)
                     /locus_tag="KRH23_002857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226134.1"
                     /translation="MYNLLKLMIEQKNYSTKEDLQHKIDVFYTVNRITEEQYLELTGL
                     LNKEETQVEPTV"
     gene            complement(24203..24550)
                     /locus_tag="KRH23_002858"
     CDS             complement(24203..24550)
                     /locus_tag="KRH23_002858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226135.1"
                     /translation="MNRNNRIIYDQTGNIWLQTGEATGDIQEWSKITELNFLDVEFGS
                     IDYSKQYIESINPVTKEPIIKDIEVILTDEQKRLQALEKELSMLKEENKNRDSEIVNT
                     AFEVENIKLNNNL"
     gene            complement(24571..26283)
                     /locus_tag="KRH23_002859"
     CDS             complement(24571..26283)
                     /locus_tag="KRH23_002859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine-rich protein"
                     /protein_id="HHS5226136.1"
                     /translation="MQTEWNFNYANYVQNVSLPPGRYKLECWGACGGAVDTSDWTDCA
                     KGGYSKGEIVFKKRTNLQICVGQSGYEKVSEGSSLTRSGFNGAGAAGKVTTGSFAYSK
                     YGGGATDIRLYHPSATWGNTESLLSRILVAGGGGGMKNNFASARSIGHGGGYVGVNGV
                     GRDRDFCGGGSQYQGGTSYDTEEYHGSLGKGGYGNIGIGGGGGWYGGAGSYSNECGGG
                     GSGYALNKDSYKAPGYIPTPEYYLENIVMTTGGNTTKADGYAKITLLQALPFLTVSSY
                     NSTQATFKADHTDPALLTKIEWFIDDVLKETITTNLTEEKTINYTLEDNALHTLKIVV
                     TDSNNATAEKVLSISKNIMPLPENVNLNDISTKLVEVNAGFKVGKTSIINTLALKNIE
                     ASLNNTLVELSEKIKTSFDSSDTSVQDLQNQVTQKNNTITQLETELSKRKRFITGTYT
                     FTKTDAENFNLSIYDKEGTSKTLTIPVNMGFSPSLIVLSGVTFSTTSKSYVYFDNVCN
                     SNFYNFGYNSDSTHSNPKAVGILNVSNVGYSSLVLTLYKLSMSEAVGIWAKEGATLTY
                     KIYI"
     gene            complement(26300..>26778)
                     /locus_tag="KRH23_002860"
     CDS             complement(26300..>26778)
                     /locus_tag="KRH23_002860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HHS5226137.1"
                     /translation="TELTSNIETAKTELNTKIDQLIAGGSNVAYTQRVAIDDWVEDAE
                     SGFKATVTHSLLTQRIVVNIIDATTKENIVPNFKIVDDNSIEIRSEVKVELNVYVING
                     NAETHFINATVDDNRVSEMTTYSSKKIEDRLVNIEEKVNGGLSNIATSVNELITYC"
BASE COUNT         8788 a         4651 c         3919 g         9420 t
ORIGIN      
        1 gccttttccg gctggtggat atagatggta tttgtcatag ttcgttttgt ggacggttag
       61 aagcccgttt tccggggcgg gcgatacttt ataccacctg ccccggtttg gggcttgcaa
      121 agcctgataa atcaaggctt ttttcgctcc taactgtcca cagcagacct ccttttccgt
      181 tcactttctg ttttctgccg cctgtgaact ctggcggcac agccggggca gtattttgcc
      241 cggttggatt tggggacgaa cacaccgccg cagaccgcac agcgtttcaa gtccttatcc
      301 cggaaaattt ccgcttccag cgtcccgtcc agcggcaaga ccgcccagcg gaaccactta
      361 cagcagaccg agaaagaaat cgtctgcggg caggtgcagg tgtccccatc gtcaagggca
      421 atgcagttgc cgtcctcaca gcaacagcac tcccggcgta tcagggcgct tgcccgtttc
      481 cgctgcgccg gggtcatgcg gtaaagggaa ccgtccggcc tgcattccag cggcggcaag
      541 tctttgtagg gattattttt catgcgttcc ctccgttttg ctttccgctg ccgttctccc
      601 cgaaaaggct tcctgcccca ttcctgcggc gtgttccggc gttggcacgc tcaccataac
      661 ttcgggacaa cttgtcccaa agtgacctct ggacaaagtg tccagaagtc ggctccttgc
      721 ggtgcttccc cagccggggg tattcctttt cggacggtca ttcggttttc aaggtgctgt
      781 ccatcgatga actaacctaa gtctacaccg aaatgaccgc ccgtcccgta tatccgaaag
      841 gtgggaaatc tgcctgaaaa tccccccatt tccacgctct cggaattgtg gtagaatgga
      901 agaaactgaa cagtaaattt gaagttgtgg aggtaacaca tagatggatc aaggtagaat
      961 tattgtaatc acaggttcgc cggggacggg gaaaactaca acggcatcta ctgttgcaaa
     1021 agaatcggat ttggaaaaat ctgtgcatat gcacacagat gacttttatc attatttgag
     1081 taaaggggca ataccaccat atttgccaga atcaaatgag caaaatttga ttgtcattga
     1141 agcattttta gaagccgcga agcgatatgc tcgtggtgga tatgatgtaa ttgtagatgg
     1201 tattgtagga ccgtggtttt tagagccgtg gctcaacatt gttcaagagc attatgaagt
     1261 acactatatc gttttaagag caagtaaaga agaaactatg aagagagcta tcaaacgctc
     1321 aaagttagac agagaaacaa atattgaatt agttgaaacg atgtgggaac aattttccaa
     1381 tttaggaatc tatgaatcaa atgttattga tacaactacg cactcagtca aagatactgt
     1441 atcagcagta aaagaaaaaa ttgtaagggg tactgcttta ctgctttagg caattccagt
     1501 ttgtcgagca gacaaggagg gagaacatgg aactatccat acaagaacgc ctgaaagacc
     1561 tgcgtgtgga gcgtggcctg acgctggagc agcttgcgga agaaacccat ctctccaagt
     1621 ctgcgttagg cagctatgag ggggacaagt tcaaggacat cagccactat gcccttatcc
     1681 agctggcaaa gttttacgaa gtgtccgttg attatctgct gtgccgttct gaaacaaaaa
     1741 atcacccaaa cgccgatctt gcagacctgc gtttgagtga tgatatgatt gaatttttga
     1801 aaagcaggct ggtggataat gccctcctgt gtgaactggc gacgcacccg gattttcccc
     1861 ggctcatggc tgaccttgaa atctatgtaa acggcatagc ggcaaagcag gtacaggggg
     1921 caaacgccat tgtggacgct gtgagcgcaa ctattatgaa gcagcacaat cccggtctga
     1981 ccgacccgca gttaaggcag ctgatcgccg cccacattga cgatgacagc ttttgccgcc
     2041 atgtgataca gcaggatata aacaagatag cccttgacct gcggaaagcc cacaaggacg
     2101 attttttcag tgtcccggag gacaatcctc tggaagattt cttgcagacc gccgaagaag
     2161 ccgccagccc aaacagcgac ccggaacagg ctgcgatggc ctttatctgc aagcggctca
     2221 aactgaacta tgggaagctg tcggaggagg aaaagaaatg gctgaaaagg attgcacaga
     2281 agtcggactt gctgaaaaat ccaaacccgc agcggggaag aaaatgagaa attagatatg
     2341 caaaaaggaa aaatgagatt cattgaagta gaaaccaaaa acaggacggc ggatttcata
     2401 aatcggctgc tgacggtatg ggaaagttct gtaagagcaa cacacctgtt tctgtcggac
     2461 agtgaaatca aaaagataaa agaatatgta ccgcaggcgc tcgctggaat tgcgcatttg
     2521 atgatcgcag aagatgatag gggctgcccc ggggctttta tggggatcaa ggacggcacc
     2581 ttggaaatgc tgttcatttc cccggaagaa agaggaaagg ggctcggaaa gcgcctgctc
     2641 caatatggga ttaaaaccta tgccgtagag cgggtggctg tgaatgagca aaacccacag
     2701 gccaagggct tttatgaaca catgggcttt caggtttata aaaggacaga ccttgacgaa
     2761 cagggcaatc cttatccgct tttatacatg agccttaaca tctaaatcgg attttacgaa
     2821 atctcatatc ccgcagagaa gcaaaaacag aaagtaccct gccttatact cattatcatc
     2881 attgcccttt tccttgactt gcttgtgtct ttgtgataca ctaacataca taaatcattg
     2941 ccgatttttc ctgatcgata cgattttgaa gtggcaacag ataaaaaaaa gcagtttaaa
     3001 attgttgctg aacttttaaa acaagcaaat acaatcattg tcgcaacaga tagcgacaga
     3061 gaaggcgaaa acattgcctg gtcgatcatt cataaagcaa atgccttttc taaagataaa
     3121 acgtataaaa gactatggat caatagttta gaaaaagatg tgatccgtag cggttttcaa
     3181 aatttgcaac caggaatgaa ttactatccc ttttatcaag aagcgcaaac acgccaaatt
     3241 gccgattggt tgatcggcat gaatgcaagc cctttgtata cgttaaattt acagcagaag
     3301 ggcgtacaag gtacattttc actaggacgt gttcaaacgc ccaccttata tcttattttt
     3361 cagcgccagg aagccataga aaactttaga aaagaacctt ttttcgaggt ggaagctagt
     3421 ataaaagtaa accaagggtc atttaagggc gttataagcc ccacacagcg ctttaaaacc
     3481 caagaggagc ttttagcttt tgtttcttct gaacaagcta aaataggcaa tcaagagggg
     3541 ataattgctg atgttcaaac caaagagaag aaaacgaata gtccgagttt gttttcttta
     3601 agtagtttgc aatcaaaagt taatcagctt tataaagcga cagcgagcca aactttaaaa
     3661 gctatgcaag gactgtatga agcaaaatta ttgagttatc caagaacaga tacaccattt
     3721 attacagaga acgaatttgc ttatttaaaa gcgaattttg gcaaatatag cggtttttta
     3781 ggacttgatc ttgaaatggt tcaaacagag cctagaaagc gttatgtgga cggtagtaag
     3841 gtacaggaac accacgccat tatcccaaca aaacaagtac ctaccgaatc tgcattagcg
     3901 aaaatggacg atttacaacg aaaaatatat gctttagtcg ttaaaacgac cgttgccatg
     3961 tttctacctg attatttgta tgaagaaact aagatacaaa ccaaagtagc cgacttactt
     4021 tttcaatcaa taggcaagac accaaagcaa gaaggttgga aaattctttt caaacaacaa
     4081 accaaagaag aagaagagga cgttcaaacg ttacccttgg ttatcattgg agaacatgcc
     4141 gaggttgacg ttaagagtgc cgaaaaagaa acacaaccac cgaaagcttt tacagagggt
     4201 acattattaa ctgctatgaa aacggcgaat aaaacggttg atgatgaaga agcaatcaag
     4261 attttacaag aagttgaggg gattggaaca gaagcgacaa gagcaagcat tattgaagcc
     4321 ttgaaacaaa aagaatatat ccaagtgatt aagaataagc ttgttgtaac tgaaaaagga
     4381 aaattattgt gccaggcagt tgaaagtcag caccttttaa cgagtgctga aatgacggct
     4441 aaatgggaaa cgtatttaaa aaaaatcggt aaaagagaag gcaatcaaga gaactttatt
     4501 acgaatatca aaaaattcat tgttcattta ctggaagctg tacctaacga tatagaaaaa
     4561 ctaaattttt ctgattacca ggaacagaaa gaaaaagaag cagaaaaaag tattgtagga
     4621 aaatgtccta agtgtggcaa caatattgta ttaaaaaaat cgttttatgg ttgttcaaat
     4681 tatcctgaat gtaagtttac tttagctgaa cattttagaa agaaaaaact caccaaaaca
     4741 aatgtaaaag aattactaga gggaaaagaa accctggtaa aaggaatcaa aacgaaagat
     4801 agaaagtcct acaatgccgt tgtaaaaatc ggagaaaagg gatatattga ttttatatct
     4861 ttctcaaaat aaacataaaa gccctttaaa gagggctttt atatattaat cacaaatcac
     4921 ttatcacaaa tcacaagtga tttgtgattg ttgatgataa aataagaata agaagaaata
     4981 gaaagaagtg agtgattgtg ggaaatttag gcgcacaaaa agaaaaacga aatgatacac
     5041 caatcagtgc aaaaaaagat ataatgggag ataagacggt tcgtgttcgt gctgacttgc
     5101 accatatcat aaaaatcgaa acagcaaaga atggcggaaa cgtaaaagaa gttatggaaa
     5161 taagacttag aagcaaactt aagagtgtgt tgatagtgca gtatcttaaa attttgtata
     5221 ataggaattg aagttaaatt agatgctaaa aatttgtaat taagaaggag tgattacatg
     5281 aacaaaaata taaaatattc tcaaaacttt ttaacgagtg aaaaagtact caaccaaata
     5341 ataaaacaat tgaatttaaa agaaaccgat accgtttacg aaattggaac aggtaaaggg
     5401 catttaacga cgaaactggc taaaataagt aaacaggtaa cgtctattga attagacagt
     5461 catctattca acttatcgtc agaaaaatta aaactgaata ctcgtgtcac tttaattcac
     5521 caagatattc tacagtttca attccctaac aaacagaggt ataaaattgt tgggagtatt
     5581 ccttaccatt taagcacaca aattattaaa aaagtggttt ttgaaagcca tgcgtctgac
     5641 atctatctga ttgttgaaga aggattctac aagcgtacct tggatattca ccgaacacta
     5701 gggttgctct tgcacactca agtctcgatt cagcaattgc ttaagctgcc agcggaatgc
     5761 tttcatccta aaccaaaagt aaacagtgtc ttaataaaac ttacccgcca taccacagat
     5821 gttccagata aatattggaa gctatatacg tactttgttt caaaatgggt caatcgagaa
     5881 tatcgtcaac tgtttactaa aaatcagttt catcaagcaa tgaaacacgc caaagtaaac
     5941 aatttaagta ccgttactta tgagcaagta ttgtctattt ttaatagtta tctattattt
     6001 aacgggagga aataattcta tgagtcgctt ttgtaaattt ggaaagttac acgttactaa
     6061 agggaatgta gataaattat taggtatact actgacagct tccaaggagc taaagaggtc
     6121 cctagcgcct acggggaatt tgtatcgata aggggtacaa attcccacta agcgctcggg
     6181 accccttgta ggaaaatgtc ctaagtgtgg caacaatatt gtattaaaaa aatcgtttta
     6241 tggttgttca aattatcctg aatgtacctt cactttagct gaacatttta gaaagaaaaa
     6301 actcaccaaa acaaatgtaa aagaattact agagggaaaa gaaaccctgg taaaaggaat
     6361 caaaacgaaa gatagaaagt cctacaatgc cgttgtaaaa atcggagaaa agggatatat
     6421 tgattttatc tctttttcaa aataagcata aaagcccttt aaagagggct tttatatatt
     6481 aatcacaaat cacttatcac aaatcacaag tgattaatca caaatcactt gtgatttgtg
     6541 attcctaatg atacaatatt actatacaaa aaaagaatgg ggcgtagtta tggagaagga
     6601 agaactcaaa atacttgaag aattaagacg tattttaaac agtaaaaatg aagcgattgt
     6661 tatcttaaac aattatttta aaggtggtgt tggaaagtca aaattatcga ctatgtttgc
     6721 ttacttgaca gacaaattta atttaaaagt tttaatgatc gataaggact tacaagcaac
     6781 attgacaaaa gacttagcaa aaacatttaa ggtagaattg ccacgtgtta atttttatga
     6841 aggactgaaa aatggaaact tggcttcttc tattgttcat ttgactgata atttagactt
     6901 gatccctggc acgtttgatt tgatgttact gccaaaatta actcgctcat ggacttttga
     6961 aaatgaaagt agattgcttg ctactctttt agcaccttta aaaagtgact atgatctcat
     7021 tattattgat actgtaccaa cgccaagcgt ttatacaaat aatgcaatcg tggcaagtga
     7081 ttacgtcatg atccctttac aagcagaaga agaaagtaca aacaacattc aaaactatat
     7141 ttcctatttg attgatttac aagaacagtt taaccctgga ctagatatga tcggttttgt
     7201 tccttattta gttgatacgg acagcacaac gataaaatca aacctggaag aactgtacaa
     7261 gcaacataaa gaagataact tggttttcca aaatattatc aagcgaagta ataaagtaag
     7321 tacctggtct aaaaacggca ttacagaaca caaaggctat gacaaaaaag ttttatctat
     7381 gtatgagaac gtattttttg aaatgcttga gcgaatcatt caattagaaa acgaaaaaga
     7441 atagaatcac aaatcacaag tgattaatca caaatcactt gtgatttgtg attgttgatg
     7501 ataaaataag agtaagaaga aatagaaaga agtgagtggt tgtgggaaat ttaggcgcac
     7561 aaaaagcaaa acgaaatgat acaccaatca gtgcaaaaaa agatattatg ggggataaga
     7621 cggttcgtgt tcgtgctgac ttgcaccata ttataaaaat cgaaacagca aagaatggcg
     7681 gaaacgtaaa agaagttatg gataaagcct tagaagaata tattcggaaa tatttacctg
     7741 acaaacttta aaaggagtga aaatgaaatg gcagttactt atgaaaaaac atttgaaata
     7801 gagatcatta acgaattatc ggcaagcgtt tataatcgag tattaaacta tgttttgaat
     7861 catgaattaa ataaaaatga ctctcaatta ttggaagtca atttattaaa ccaattaaag
     7921 cttgcaaaac gtgtaaatct ttttgattat tctttagaag aattacaagc cgttcatgag
     7981 tattggcggt caatgaatcg ctattcaaaa caagttttga ataaagagaa agtggcttaa
     8041 tatggcaaat atagtcaatt ttactgacaa acaatttgaa aatcgcttaa atgataattt
     8101 agaagaattg gttcaaggaa aaaaagcggt tgaatcgcca accgcttttt tacttggtgg
     8161 gcaaccaggg tcagggaaaa cgagtttgcg aagaagatga ttgagcaggc aggaacaaag
     8221 tgataaattc aaattgtgag ggaaaatata gatgaatcaa ggaagaatta ttgtgattac
     8281 aggctcaccg gggacaggaa aaacaacaac tgcgtcaatt gtcgcaaagg aatcagatat
     8341 ggataaatca gtgcatatgc acaccgatga cttttttcat tacttaagca aaggcgcaat
     8401 accaccacat ttgccagaat ccaacaagca aaatctggtt gtcattgaag cctttttaga
     8461 ggctgcaaag cgatatgctc gtggcggata tgatgtaatt gtagatggga ttgtcgggcc
     8521 atggtttttg gagccatgga aagctcttgc ccaagaagat tacgaggtac actatattgt
     8581 attaagagcg agtaaaaaag aaactatgaa gcgagctgtg gaacgctcaa aattagatag
     8641 aaaaacaaat attgaattag tggaaacaat gtgggagcaa ttttccggtt tgggagtata
     8701 tgaatcaaat gtcatagaca caactacatt cacaattaaa gatacggttt ccgcaataaa
     8761 agaaagagtt gcatgtggga cgtctttact atcttagaca ttcccatttg tcaggaagat
     8821 agcaaagcca gccgagccag tcaacggtca agatgaacgg cgcatttcat gcgccgccgt
     8881 tgacagtcac gcccgtcttt gctaaaaagt aatcaaggcg ggaaagccct aaaatggctt
     8941 cccgcccatt tcaattttta gaaaagaaac gctccaaaat cagaaagaga gcggccaagc
     9001 actttgaggg attggccgcc ttgtccaccc attcagcggg acagcgggcg gaggtcaagg
     9061 ccgggtgtaa acccgttcat ttcagccttg acggttgccc gctgtcctgc tacttttccg
     9121 ggagtgtggc cacaacttcg ggacactttg tccacaagtc ggagcgtagg acgagggacg
     9181 ggggctttca tatacctgcc gccgttctct gaaaacagcc cgatttttcg ctcattccca
     9241 ttcgcaaaaa ttcagcctgt tttcctgccg gagcaaacag ggcgcatgaa gcaccgcacc
     9301 ccgttttcca cgccagccac gccagcaggt ataacacact acactttgct tcgcaaagtc
     9361 gtgtgccaaa tgggggcttt gccccctttg gaaaccccca caagaaaagg cggtacgcta
     9421 cccctccacg gggcgcatac cgccttttct tgttatccag ccctccggct gtatcggttg
     9481 agcaaaagtc agcatgggat tggtgtggta tctttaatta tgtgaaactc cactctccca
     9541 cttagatact gctggtgttg acacacctat aaactttgct aattgttctt gagttaaatt
     9601 tcgttctttt ctaagacact gtatgacttt acctatttta atttgcatat atacctccct
     9661 agtacatctg ttgtaattta agtatataaa aaaaatattt actagtaaat cgagggaaag
     9721 ttaacaaaat gtttgtaatt taaccattgg ttatatttta atctaaaacc ctatctcatt
     9781 agcttgaaat ataaaatcta ttaattaagt ttaagtataa cctaattaat agattcacat
     9841 taaatagcat ttaaatattt agattttctc tttactacaa cttactatat ttaaactttc
     9901 aaggaatttt aaataaaata aattccatat acaatgataa taatactgag tgttaataat
     9961 ttatttataa taacacccac ctattcaata aatggcatta tagcaaaaaa tcacttctgg
    10021 gctctctctt ttctactttg catatacata atccactttt caaatattat atataaataa
    10081 atttaaagca aatatatcat tatatttttt tattacaata tttctatttt attatttaac
    10141 caacaaatta tatcctcaaa aacttcttct ctatttattt cattcaacaa ttcatgcctt
    10201 ccatctttgt aaagtttgca agttacatct tttactccta attttatata tctatccctt
    10261 agtcttaaga ctcctttacc attttttcct atggggtctt tatctccaga tattatgtaa
    10321 ataggtatat caagtggcac tttttttaag ttttctttat cctcaatttc ttttaaccct
    10381 tgaactaaat cataaaaaaa gccacaacta cacactactc cacaaaatgg gtcatttata
    10441 tatttttcaa cttgttcttt atctctactt aaccagtcaa acttagtctt ttcatttctt
    10501 cttattattt cgccgccaaa tatcaaatta tttattttat tacttttaaa acgtcttcca
    10561 tactttttaa tctcatgatt gattatcaga tgagcaagat ttagaatgat tccttgcttt
    10621 ccatttgaac cacatagtat aagtccagat aaattattac tgtaatccat tatatatctt
    10681 tgacttgcaa atgaacccat gctatgtcca aatagataaa ttggcaaatc ttcattttct
    10741 ttctttataa tatttgttaa agtatacatg tcctctacaa gacatctaaa tccttctttt
    10801 tcagctaaat gtccaacatt ttctattatc tttgcagttt ttccatgacc tctatggtca
    10861 ttgatatata ctatataacc atttttagta agtaccttgg caaaagtctc atacctttgt
    10921 gcagtttcag ccattccatg tgcaatttgg ataactgcct ttggtttttt tatattttca
    10981 tcttcccatt tatatgtata tatatctaaa ccttcctctc ctttgaaagt aaagtttgta
    11041 cacttcataa ttatccctcc agattgattt tattcagtat attaatttat atattatatt
    11101 acaagtattt tcaagtcaaa atctttctaa aaaatttaag aattattaat tcctcataga
    11161 agttatcatt ggtacataga agtttttaca taaaattata caataattta attaattaat
    11221 agttacataa aaaagtaata ctttaatata ttttgacacc atattgacat tagaattaat
    11281 tcatgatatt ctgttttcga caaaacaact tctaaaaata aaggagatat atttcatgga
    11341 ttattcaaat gaactaaaag agctcttttt aatgaatcaa acatatgcaa ctctttttac
    11401 ccttacaaac aaaatacaaa tagaaggaga taaatatttt ggtatactta cttcaagaca
    11461 gtatatgact attttatcaa ttcttcattt accagaggaa gaaacaacat taaataatat
    11521 tgcaagaaaa atgggtacaa gtaaacaaaa tataaataga ctagttgcta atcttgaaaa
    11581 aaatggatat gttgatgtaa ttccaagtcc tcatgataag agagcaatta atgttaaagt
    11641 tacagactta ggaaaaaagg ttatggtgac atgtagtagg actggaataa actttatggc
    11701 agatgtattt cacgaattta ccaaagatga attagagacc ttatggagtt tactaaaaaa
    11761 aatgtatcgt tttaatggtg aagaacaaga tggctttgaa gaagatgcta attttatgga
    11821 atatgaagaa atagataaaa ttaaatctga agcacttgaa gaatttgcaa aaagaagaaa
    11881 tagggtaaat aaaaacgatt aatactatcg catctataat accacttttt tatagtacaa
    11941 tattttatat aactataatg tcatttttat tttttaacaa aacaatcatt acatagatta
    12001 ggtgttctta ggaactcttt ttctgttttt tgtacaaaaa aaggagatga ttagactttt
    12061 attttaaagc atctcctttt tcactattat gattattcta ctcctaaaat catatctttt
    12121 aatttttgta aatcattaat tggttgacta caactattac tttgacacac gtaataacta
    12181 gtcttatcat ccttcaatat atagttattt aaaaaaccta taatagtgtt ttcttcattg
    12241 tatttctttg ctaaaaaagt tgcatttggt ataaaatttt cacttatcaa ttctttaaat
    12301 gcaattaaat cagaatcttc cttaaaaata catataattt ccttagtaga ataaagttca
    12361 aacatcaatg aaagcatata aaagctgtag ccagttggag aaccctttac attatccaca
    12421 tacagtttta attgtttata tgacatttct tcaagtctat tatctccagt aattttcgca
    12481 agtcttataa gattgtataa ttgaacagaa tttcctgatg gaatagctcc atcatacaaa
    12541 tcttttggtc ttgctattaa attttcacta tctttaccat atatataaaa tccacttttt
    12601 tcataatccc aaaaaaggtt gatacagctt tcattcaaat ttaaagcctt ttctaaatat
    12661 ttcatattaa atgttgactc ataaagctct atatacgccc agattaaaaa agcataatca
    12721 tctaaatatg ctaaatagtc ggaacttcca tctctatatc tagctaataa tctacctgac
    12781 tcatttacaa gattattatt tataaagtta agacacttat ttgaatactc taaatatatg
    12841 tcatttttta aagtactata tgcctttgtt aaagcaacta tcatcaatgc attccatgat
    12901 gtaagtatct tgtcatcttt atgcaaagat gttctttctt ttctatattc aaataccttt
    12961 ttactaaggt cagctatctt ttcattatgt ctctcatatt ctttattttt tatgagatta
    13021 ggaatacttt tgccttcaaa atttccacta ctagttatat caaaataatt attaaagaaa
    13081 gttccatctt cttcacccaa aacttcaatt atctcaagag gattaaatgt ataaaattta
    13141 ccttcttcac cttcactatc agcatcctgt gctgaataaa acccaccttc tttatccttc
    13201 atctctctaa ctacataatc tatagttttt atagcaattt ctttatacaa ctctttcttt
    13261 gttattttat acgcatctaa aaaagctata gtaagcatag cattatcata tagcattttt
    13321 tcaaaatgag gagccaacca ctttttatca gtagagtatc ttgaaaaccc aaatccaata
    13381 tgatcaaaca agcctcctct atacattcca tctaaagttt tttccaccat ttttaacaca
    13441 tctttgtctt tttctatact ataatatttc atcaaaaaca taagattctg aggacttgga
    13501 aatttaggag cattaccaaa accaccatac ttttcatcat aaatagcctt aaatactcta
    13561 actgatgaac tcaacatctc ttttgataaa tcaccctcag tattttttac accaaaatca
    13621 tccttaagag cttctattat ttcatctcca gattttatta atatatctct gcttgtattc
    13681 catttttcag atacattctc taataaatct ataactccag gtctattata ccttgaatat
    13741 tttgggaaat atgttcccgc aaaaaaaggt tttttatctg gtgtcattat tatggtcatt
    13801 ggccatccac cactacctgt catagcttgg caaactgtca tgtacacgct atctacatca
    13861 ggtctttcct ctttatctac ttttattgcc acaaagtttc tattcattat ttcagcaact
    13921 tcttcatctt caaaagattc tttttccata acatggcacc aatggcatgt tgaatatcct
    13981 acacttaaaa atattggctt atcctcttct tttgcttttt taaaagcctc atcattccaa
    14041 ctataccagt ttataggatt atatgcatgc tgtaaaagat atggagattt ttcatttatt
    14101 agattattag gttttctatt actgtccaaa ataccacctc atttgttatt ttattatatg
    14161 ttttgcaata aacaaataga tatacactta taataagtgt atacccattt ttaaccatac
    14221 atatttaatt tttcatataa ttaattctcc tagtaaataa tttttataac tactaaaaca
    14281 aaacaacata aaaaatatca aattattttt ttaaaggttt ttcaaaagaa ggaggattaa
    14341 tatctatctt agtatcgtga tttggtcctg gagtagacaa atcgaaatat aatttagaat
    14401 cttctgtaac tccaaaatct ctatttgaac ctgtatcttt aactttattt aaagcatctc
    14461 taaatagagc attatgtgct tcttctctat taagcaagaa atctattgtt tcttttacat
    14521 atttatcatc tatttgtcta tacaagtact cataaactac cttagctctt tgttcagaag
    14581 ctatatttga aagtaagtca gctactaaat cccctgtaac tgtaacgtaa ttagcagtcc
    14641 aaggagctcc tgatgagttt attaagactg gtgatagacc agttaataca tgtgtttcta
    14701 tttcgcctgt attaactgaa ttataatcaa catcatgtcc atttaataaa tttatagttt
    14761 gtgctaccat ttccatatgg ctaagctctt ctgctgctat atcaagaaat aaatctttta
    14821 tttgagggtc ttttattcta aaactttggg acaagtattg catagctgct tttaactctc
    14881 catttgcacc acccaactgt tcttgcatta aaacagcata ttgaggattt ggtctttcta
    14941 cttttacttc ttttaataat gctttatcgt gtttaaacat atgaatacct ccgtaaatta
    15001 ttattcaaaa ttattattta cttaagttgt aatattattc taggttattt gtttattgtt
    15061 gttatttttt acaagtgttg gtatttcaat gttttattaa ggtcagtttt gttgtttatg
    15121 ttttattatg tttaatttaa atttattcta ttatttattt tcggtggcaa aatggtggca
    15181 agtttggttt tgtcaccatt tatttttatt tgtaaaaaat atagtttgtc aatataactt
    15241 tattgaaaaa tatggaaata aatattgctt ttgccggttc ggcatattat aatataaata
    15301 tagaaagggg gtgaaaagga aaatgagtag aatagaaaga agaaaaaaag atagagaaag
    15361 caaactcgcc aaagttaaaa ctgctctctc tatcttaccc attttaataa atttaattga
    15421 taaactaatt aaattattaa aagatttata gttttgtaag ctaggaagaa tttaatcttc
    15481 ttcctagtga cttctttcta aatattataa cacattttct ataaaatatg agtgataaag
    15541 tttataaatt ctgtcttatt atagttgcta taactatagt aatagacata atacttttat
    15601 ttttacattt taatatcaac aatataatag gattaatagt aagcatttta ttgttaatat
    15661 ttgttacatt acaatataaa aaaggaggaa aatagtttgg agcaaaaaga atctaaaata
    15721 gtttacagta aaggtggttc aggtacttat tcggctaaaa tttctttacc tttaagccaa
    15781 cttgaaaaaa tgggatttac aagggaaaaa cgtaaggctg tagttatttt taaggaagat
    15841 gagattataa taaaaaaatc tgatgaggaa taactctaaa ataagtgggt gtataatgta
    15901 aacatccact tatttttatt atattttgta ttttatatta atatatttta taactttatt
    15961 gaaaaatatg gaatatttat tggctttcac gtcacgtgat gatataatat aaatatagaa
    16021 aggaggtaag aaagtgggga gattagaaag aagaaaaaat aaaagagaaa acaaatttaa
    16081 taaaattaaa aatgctttct ctttcacatt agttttaatt aatctagtac tcgcaatact
    16141 aagattgatt aaagaattat aagtttcaat cctaggagga aaataccttc cttctaggta
    16201 gcttctttct aatattataa cacattttct aatttaatat gaataataaa ttttatagaa
    16261 tttgtatgat tattcttggt atcactatag ttttaaatat tattaatata ataataagtt
    16321 ttacttttaa agctcttatt gctttggtat ttactttatt attgctggca tttattaata
    16381 gtagaaagga atgatattat tggagcaaag aaaacttaga attggattta ataaaagtgg
    16441 caaaggctct tttacaccca gattgatact tccaatgtca tggattaaag agatgaatat
    16501 ctctcctgat gaaagggatg ttcttgttac ttttgaggat ggaaaaataa ttattgaaaa
    16561 aactgaaaat gaataaaaaa aggaggtagt aactatttcc agttactacc tttcaatcta
    16621 tttaactaag ttttctactt cattaaatgc tttttcattt ccatttccac caatttgagt
    16681 tatattttta aactttttat tcttgattaa ctctttttgg ctattatcca atccatttcc
    16741 aactaatact actggagatt cagttttacc tgcaagcact cctactgata aggcatctac
    16801 taaatcgtct tgtttattca ttccattctt agctacatat aagtcattaa gtgtatcttt
    16861 gctatagaaa tgacttatta cttttgagtt agtttctgtt ctatcagaac ctgctatttt
    16921 agttacagat ggtaatgtat tattcacttc tttattatta aataaagatt ctccacctat
    16981 tacatatgat tttgatatgt ttttattagc tattaagtct tttatatctt tcatatcatc
    17041 attttgatta gtaagaagaa ttggcatttc ctcttttgct gatatagctc ccatacttac
    17101 tgcatcagct agtccctttt ctccatttac cactactact tttgacaggt tagaattttt
    17161 gtctaattct tttgcaagtt ttattgatgt ttcatatcta tcatttccag atattctaat
    17221 tacatttaat ccttttttct ttaaatcaga cactactttt tcatcaacag actttaatcc
    17281 gcccactatg tacacatttt ttgcttctaa tctatttatt tctttttctg ttaatttatt
    17341 taagttatta tttttagtaa gtaatattgg tgcatcttta gacttagcaa atggtgttgc
    17401 tgataaagca tccgatatgc tagagtcatt tattaacact atattatcag ctttattcca
    17461 tcctttttga cttattttca ctgatgtttc atttctgtct acacctgtta atttttcctt
    17521 agatggtgtt gaagtaggtt cagaggactc ttcatttgta gatgatgaac ctcctccact
    17581 ccctgacgaa cctcctgttg atgttgattt tttttgattt gaccaatcta attcttttaa
    17641 ttttgtgttt ttgcttacat ctaagctggt taatctattt tccccacaat atagccttac
    17701 aagttctgta ttttttgtta catccaagct agttaattca ttttgtgaac aatataagta
    17761 tttaagattt ttatttttac ttgtatttaa actatctaat ttatttttat aacaagttaa
    17821 attttctaag tcaatatttt tacttatatc taaagctttt atttcattgt cataacagta
    17881 taattctaaa agttctatat tattctctat attcaaattt gttaacttgt ttgctacaca
    17941 ctctagatat tttaaattct tattgctact tatatccaaa ttcttcagat tacttctact
    18001 acaagttaaa tcttccaaat taatacaatt ttccacattt aaagtactta attgttcttg
    18061 attacaatat agttttacaa gcttttcatg attttttaaa tttaaatttt gcaatttatt
    18121 gttgtgacaa attaacttaa caagttcttt attattatct aaatttatat tttctaattg
    18181 attaaaagaa cagtttaaat cctgtaattc taaatttgta gatatatcta aatcatttaa
    18241 attattataa tcacatttca aaatttttaa tttctgattc ttagataagt tcaaactagt
    18301 caattcattt tcaaaacata aaagagttgt caaattagtt gctttagtta tatctaaact
    18361 ctttaaatta ttttttctac agttcaattc gtctaattta gaattttcta taactaagtc
    18421 tgttagatta ttttctccac aatgcaacgt tgttaactct ctattattac ttaaatctag
    18481 acttgttaat tgattttcgt tacaatacaa ttcttttaaa tttatgttgc tacttaaatc
    18541 tagactcgtt aaattatttc ctctacaact aaaattttct aatccaataa aataattaat
    18601 tccagataaa ttttttattg atttgctccc taaggttaaa ccttttgtag attctataat
    18661 cgctttttgt gaaattccaa ttggatttcc atcatctaaa atacttagtt tatcacaaat
    18721 tacttttcta aaattttcat ctggaaaagc ttcttccatt gtcatatttt ctaagttatt
    18781 agctttcctt gtttcatatc taacttccct atttttctca atatcttgtg catttatctt
    18841 atgtaccaaa ggtgatacaa ctaccaatga aagtgataaa ataactgctt ttttgcttaa
    18901 atttttcatc cccacacctc attcaaataa tatttaccca cttgaattgt atcacataat
    18961 attaacctta gaaacaaact ttaatattat tatataataa attatttttt tattatgaat
    19021 gaggcattag aagataacaa ctacttttag ttgctacttt ttaatttatc tattaataaa
    19081 atctaatgcc ttataaagtg tatcaaatct atcattaccc tttatcatag taaatttttc
    19141 tttagtcata gaaccaatct tctcacatgc tgcaccacca atgacataaa gattttgcgt
    19201 ctgacctggc acgtaatctt ttatatcaca tatcagtatt ttcccatcat tataacccca
    19261 accaactaca gttgcagaga ttttgtcaac ttctccatca taaacaattg tatgtttgta
    19321 catctgttta actccctcat tatttatatt tttatttaat acaccttcta caattaactt
    19381 agcaatacct tcatgaccta gtttcttagc tttctcataa tcttctttat tatcacagaa
    19441 gaaactttca attaatactg ctgtaggatt tgaactattt aagatatata atcctttatc
    19501 taatttagct cttctatttc taaatactgt acctagctta ttacatattc tagttgcata
    19561 ttctaaacct ttattactat aatatagaac ttctgaacct tttccttgac catcacttgc
    19621 atttagatgt agttctataa gtaaatcata tcctccacta ttaactctag gtattttata
    19681 agtcttttct tctgctttag ttttaaactg cttttcaggg catattatta catctgcctt
    19741 atgaccctct tttctaaatg tatctgctaa tactggtgca agagatttat tgtattggta
    19801 ttcgttaact actccatcag cagaagtgca tgcaccactt tttaaaatac tgtgtcctac
    19861 tgtaatacat attttcatta tttattttcc tccttctttt caataaaaaa acacttacat
    19921 atagtaagtg tttataaact tcttaaagta actattttat ttagccaata tctctatcca
    19981 attattagga aaaccaataa gctttaagtc tatagaatta ttataatcat taattaactt
    20041 ttgaagtttt ataaaaaaac tattccaaat taatttatcc atagtcaaat gcttcatagc
    20101 aagtatataa gaaaatatct ttttattatc caagttatac tttttatatt cgttttttat
    20161 tgttataata cggaaattat tattatatat tctaccataa tgagcgcatt gatttctgac
    20221 ctgtgttaat gattgtaacc aagatttaac taataaagta ttcactctac acaaattatt
    20281 ttttatgtat ctagtatctt ctggcaacat gtttgaatat aattttgaca acataccaaa
    20341 agtcattatt tccgttgcaa cccaaatggg aagttttcct tcatattttt ctttatggtg
    20401 tataataaaa agcttatctg aattattatt tttttctctc tctaatgctg tcaaaaaatt
    20461 aatatagaat ttttcatctt tgaaactctc cctttctaga tatccacaag caccatgttt
    20521 aattgctaat gtatatgcaa tgtatgtcct aaatgctatt tctatgctcc ctaacaaatc
    20581 tgttaataat atcctaaatt ccttattaaa cctatatata tcataaactt cttcaaacgt
    20641 agttccttct ttatatgagc catcatcatt cttaaaactt agaagatatg ctgtaaacct
    20701 ataataattg acattactta atacaaattt agcatcttct ttatcattta ttattaatcc
    20761 tctacttttt aaaatatcta tttgttcatc aaatgttttt tcttctttta cttcaaccat
    20821 tgttttcacc ttttcataga tatactttta tataataaaa cccaccaatt aatattagtg
    20881 ggtaaattta tctgtcccgc ctatttgagc tataaaagaa gcttggcggg ttccttcaaa
    20941 aatcaatgtc ccgtatattt gagcatataa atgctttacg agttctgtac tattattata
    21001 tacttattag ctataaaagt atactctatt taatgaaatt ttttaaattt ttgtgagtaa
    21061 taatattttt gttaatttca ttacttttca ccatccttca actgtttgta agtttgattt
    21121 atacctattg caactcccca acaaattaca ccttgtaaga ctgcaacagg atttaatcct
    21181 agcatccata ttgagaaacc tattccaagt atcagtaaca ctactggaat gtatttatta
    21241 tctaattgtt tatatttttt acaaccttta cctataatag agagagcagc tactaaaatt
    21301 agtaactgct ctggtataaa acttattaaa ttatccatat cttaacctcc taattaatta
    21361 aaatattcct ctttgtattg caaatataaa gaaccctata agtgttgtaa tcattgtacc
    21421 aattagccat ttgagcatac ttgtaagtga gtttagattc tcacacaatg cttttaactc
    21481 tgctttagac tctatatttg ctatttttaa ttcgtctatt tcttctccat gcttatttat
    21541 tcttgtttca tgtcttttta aatctgcttc gaaaagttct tcattcatgt aagcctccta
    21601 attaattgaa ataaaaaaga atcctctata cagtaggttc tgctccttct actactccac
    21661 tctgtttaat tatataatcc tctactgctt ttctgtattc tgtgttagtt acatcatcca
    21721 gctgaaactc tctatttttt aaggggttta atcctccgct taatattctc tctgctaata
    21781 ttcttactac aacattattt atattcatta taaaattcct cctacttttt cattttctgc
    21841 aatcaatatt tgattttcta attcttgtat tctcttttct tcttcactca tatatactgg
    21901 tatttcttct aagattggtt gcttagttct tatatctatt cctattattt tgtacttatc
    21961 ataatcaaca taatcgtatt ctaaatctat atattctatt tttttaatat tttttcgctc
    22021 tggaacattt cctttcgatt gtccttcata gaatattatt tcgccttctt catcaaaaaa
    22081 tattcttctt cctacttcta tatattcagt catagtttcc tcctttaact tattttttaa
    22141 gcaattgcat agaaaaaatg tggtattttg taatctttca ctggtaaaat acaagtgtga
    22201 cctactacac aatcgaatgt gttcggcgtg tacatttcac caaaattact aggttgaggc
    22261 actgctgtta taatattacg aaaagatgag taaaaaacaa aactacacaa atctatattg
    22321 taagcatttc tatagacaat aataaatttt ggagtaaaag ctaagttaaa acttattgcg
    22381 tttgctgaac aagtttttgg cgtattatta tctacttgat agagttgaaa agttttttct
    22441 ccaacttgag tacattctcc ttgtgcaata aaaatatttt cgattccaac tactttacta
    22501 attagtgaat gaagtgtttc agttgattga gcagatatat ttttcataga caaactaatt
    22561 gctaatgtat ttttcaaggt ctgtattttt gttttagtta cacttagctt atcagttcca
    22621 acaaaaggac ttcctaatgt actagctata ttatttttac caatttgcaa ttcatctttc
    22681 acgttctcaa aagtggttat taagtcactt aaacttgcat tttcgtttaa tttttctatc
    22741 ataaaaaata tcacctttct atttttagta actatttgtt gagaaatggt tactttataa
    22801 aatagaaaag tgattgaatt taaacaattt ttacaagata tatatagtat agataaattt
    22861 attttaaata gaaaaagaag caaaataaac aagtataaga ctttttagta accatttctc
    22921 aacaaatagt tactgttata aaatttcgcc ttttaattcg tttgttaaca actcattttc
    22981 taattcttca taactaagtt tttcgtatat tggattatct gacaaaatta tatatttacc
    23041 ttttaatgtt tctgataact ctattacata taaattgtta ctttcattaa ttattttttc
    23101 tttttcctct aaagaatcgt aataaaattg ttttttcata cctaatctcc tatcttaaca
    23161 gtgtaacgtc agaaactgat gtgtaagctt ttgcagtaga actattcccc gttccaacat
    23221 ctgttaataa cacttgtatt tttaattgtg tatcattatt tacaattata tctttttcaa
    23281 aattcataga acgaccactg gcagtagcat cacatgaaag ataaatatat tctttttttt
    23341 caccatatat tatttctaat ctggaacttg caaaagtagc ccagttttta taaaccatca
    23401 aagttccttt aatccttaaa caacctttaa tattaggttt atcattataa ataatgtacg
    23461 gattatttac ttcttctact ctttctgtat ctttacattt aacaattaat attgattgta
    23521 ctataaaatt tatcgcatta attaaatcag taaatgaact ttgtgtactt gctgacactc
    23581 ctttatatat taaattattc actaatacac tttttaatgt ttctattttt gttttagtta
    23641 tatctaattt atctgtgttt aaaaatgggc tccctaacac agttgttata ttacttttgc
    23701 tattctgaaa atcagtttgt acaccttgta gtgttgtcat aagttctctt aaactagcat
    23761 tatcagttaa tttttccgtc atattttcac ctcgcttata tcatatctat taaatcattt
    23821 gctattgtaa ttccttttgc tctctgtcca tttacctctg ttgccaattc tttcaatgct
    23881 acctcaacat tatcactttc aaataagttt tctgtatctt ctatagttac attctttgct
    23941 tctaatacaa gatttctaac tttattaact aactccttaa aagtcattta atcacctctt
    24001 tcaataaaaa agaacctccc ttaaactgtt ggttctactt gtgtttcttc tttatttaat
    24061 aaacctgtta actctaaata ctgttcttct gtaattctgt ttactgtata gaatacatca
    24121 attttatgtt gcaaatcctc tttagtgcta tagttctttt gttctatcat aagttttaat
    24181 aagttataca tgttaattcc tcctataaat tgttatttaa ttttatattt tctacctcaa
    24241 aggctgtgtt tactatctca ctatctctat ttttattttc ttcttttaac atgcttaatt
    24301 ctttttctaa tgcttgtaat ctcttttgtt catctgttaa aatgacttct atgtctttga
    24361 tgattggttc ttttgtaact ggatttatag actctatata ttgtttacta tagtctatac
    24421 taccaaattc aacatccaaa aaatttaatt cagttatttt tgaccactct tgtatatctc
    24481 ctgttgcttc accagtttga agccatatat tgcctgtttg gtcgtaaatt attctattat
    24541 ttctgttcat attatcacct cattttttta ttaaatatat attttgtaag ttaatgtagc
    24601 tccctctttt gcccatattc caactgcttc tgacattgat aatttatata atgtaagcac
    24661 taatgaagaa tacccaacat tagatacatt aagaatacca acagctttcg ggttactatg
    24721 agtagaatca gaattatagc caaaattata aaaatttgaa ttacaaacat tatcaaaata
    24781 aacataagat ttacttgttg tactaaaagt tactccacta agtacaatta aactaggaga
    24841 gaagcccatg ttaactggta tagtaagagt ttttgaagtt ccttctttgt catatatact
    24901 taagttaaaa ttctctgcat ccgtttttgt gaatgtataa gttcctgtta taaatctttt
    24961 tcttttactt aactctgttt ctaattgagt tatagtattg tttttttgtg ttacttgatt
    25021 ttgtaaatct tgcacactag tgtctgaact atcaaaactt gtttttattt tctctgataa
    25081 ctccacaagt gtattattta aacttgcttc tatattttta agtgctaaag tgtttataat
    25141 acttgttttc ccaactttaa atcctgcatt aacctcaact aattttgttg atatatcatt
    25201 taaatttaca ttttcgggca gtggcattat attcttactt atacttaaca ctttttctgc
    25261 tgtagcatta ttactgtctg taacaactat tttaagtgtg tgtaatgcat tatcttctaa
    25321 tgtataatta attgttttct cttctgttaa atttgttgtt atagtttctt ttagtacatc
    25381 atctataaac cattctatct ttgtaagtaa tgcagggtct gtgtggtcgg ctttaaatgt
    25441 tgcctgtgta gaattataag aagatactgt taaaaatggc aatgcttgta gtaatgttat
    25501 tttagcataa ccatctgctt tagtagtatt acctccagta gtcatgacta tattttcaag
    25561 ataatattca ggtgttggta tatatccggg tgccttataa ctatctttat ttagtgcgta
    25621 accacttcca ccacctccac attcattaga ataagaacca gcaccaccgt accaaccccc
    25681 tccaccacct attcctatgt taccataacc tccttttcct aatgaaccat ggtattcttc
    25741 tgtgtcgtaa cttgttccac cttggtattg agaaccaccg ccacaaaaat ctctgtcacg
    25801 accaactcca ttaacaccta cataaccacc accatgacca atagaacgag cagaagcaaa
    25861 attatttttc atacctcctc caccgcctgc aacaagtatg cgtgaaagca aactttcggt
    25921 gttaccccaa gttgcactag gatgataaag tcttatatca gttgctccac caccgtattt
    25981 agaataagca aagctaccag tagtaacttt gccagcagcg cctgcaccgt taaaaccact
    26041 tctagtaagg cttgaacctt cagaaacttt ctcataaccg gattgaccga cacaaatttg
    26101 tagattagtt ctttttttaa atacaatctc accttttgaa taaccacctt ttgcacaatc
    26161 agtccaatcg cttgtatcga cagcaccacc acaagcaccc caacattcta atttatatcg
    26221 cccaggtggc aatgaaacat tttgtacata attagcataa ttaaaattcc attcagtctg
    26281 cattttctca ctctcctctc taacaataag ttatcaactc atttacactt gttgcaatat
    26341 tagataaacc accatttacc ttttcttcta tattaaccaa tctgtcctct attttcttag
    26401 atgaataagt agtcatttca gatactctgt tatcatctac agttgcattt ataaaatgag
    26461 tttctgcatt tccatttatc acatagacat ttaactcaac ttttacttca cttctaatct
    26521 caattgaatt atcatcaact attttaaaat ttggaactat attttctttt gtagtagcat
    26581 ctataatatt tacaactatt ctctgtgtta ataaactatg tgttacagtt gctttgaatc
    26641 cactttctgc atcctcaacc caatcatcaa ttgcgaccct ttgagtgtat gcaacatttg
    26701 agccacctgc gattaattgg tcgattttag tatttaactc tgttttagca gtttctatgt
    26761 tgcttgttaa ttctgttt
//
LOCUS       DAEORM030000052        25893 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.052, whole genome shotgun sequence.
ACCESSION   DAEORM030000052 DAEORM030000000
VERSION     DAEORM030000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 25893)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25893)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 25893)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25893
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.052"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            complement(709..1581)
                     /locus_tag="KRH23_002861"
     CDS             complement(709..1581)
                     /locus_tag="KRH23_002861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HHS5226138.1"
                     /translation="MEETNEMKDSKHLISNIQSQYTRLSKGQKLIAQYILNNYDKVAF
                     MTACKLGETVGVSESTVVRFANALGYSGYPKLQAALQELIKNKLTTVQRVEMAHDYSD
                     DFAILNKVLKSDIDNIRSTLEEIDERAFKEASNKLLRARKIYILGMRSSFVVAQYLGF
                     YLDIILDNVHIIRMDMGDAFEQIVRINEEDVIVAISFPRYSKKSYQIVNYAKEKGAHV
                     ISLTDSLFAPVASLADNTLLVKSNMASFVDSLVPALSISNALAISVGMKEKEDIKQHF
                     DDLEQIWKRYSVYE"
     gene            complement(1975..2553)
                     /locus_tag="KRH23_002862"
     CDS             complement(1975..2553)
                     /locus_tag="KRH23_002862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HHS5226139.1"
                     /translation="MAYAKYLTKITDINKFYLENIINEGDIVIDATMGNGYDTRYLAE
                     KVGEKGFVYAFDIQEEAIKSTRKKLEKEGYTDRVKLIFDGHEKMNQYIKEEVSCVLFN
                     LGYLPRAKHSIITKPDTTLKAIKLSLEMLKENGVISIAIYTGHDGGQEEKDCIYNLVN
                     NLNQDEFNVLESKFLNQVNNPPQLILIEKKKA"
     gene            complement(2611..3327)
                     /locus_tag="KRH23_002863"
     CDS             complement(2611..3327)
                     /locus_tag="KRH23_002863"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_function: GO:0140098 - catalytic activity, acting on
                     RNA [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HHS5226140.1"
                     /translation="MRINKYIASCGIASRRKAEEIILGGRIKVNGSVVKELSFNIDEE
                     KDIVEFDNKKVKPSENYIYIVLNKPEGYITTVKDQFNRPSVIDILKDVRERVYPIGRL
                     DYETSGLLILTNDGDLTYKLTHPKHEIDKTYVASVKGIISDDEIRQFETGLKIEDYTT
                     APAKIRVTKENKEKNYSVCEITIHEGRNRQVRKMCKAINHPVLNLRRISVGKIVLKDT
                     KVGEYRYLTEDEIKYLKSIK"
     gene            3563..4603
                     /locus_tag="KRH23_002864"
     CDS             3563..4603
                     /locus_tag="KRH23_002864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HHS5226141.1"
                     /translation="MFIGILFFKFINTPSDFISSIEGFLKFFSPFLLAILLALLLNPL
                     VMLFEVKFKAHRLLAIFLSYIFIGFILAFAIRLLIPSIANTLNRLINEMPMYTDYIDS
                     FIEKNMSNIDFLKTLIPHIQHSLDNLLKEASNFVGKIPKNFLIYTLSISSMLFNMTMG
                     FILSIYIIYDKEKIALEFKRFLYSSTARNKADNIIEFFRTTHDIFYDYLLGRILDSLI
                     IGIIAFLGFQFVIRIENALFLASIIFLGNIIPYFGPFIGAIPPIAMTILYSPQKTIWV
                     IAFLFILQQLDGNFIEPKVMGNQVGIGAIWVISAILVGQSLFGFIGVFLSVPIAAVVK
                     TYVDKYIDNRLQ"
     gene            complement(4758..5417)
                     /locus_tag="KRH23_002865"
     CDS             complement(4758..5417)
                     /locus_tag="KRH23_002865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HHS5226142.1"
                     /translation="MRGRVILLISILSIFLVGCSFNKKDEINLVEQGKTYLEKHNYKK
                     AMESLSSALEEDSTNENARAMYMQAMRMSNMTEFEELKNYEGAIKELKLIEKIKNGSS
                     VIKEEATKKKEELTKLEKEQNEAEEQRKKKAKDTAGEDRYRVESDARKSSYSGSSKNN
                     KSSSKNNDKKSDSNKSDNNNSSSQNQEKPNNSNPTPAPTPQDTTGGSDSGGNSQNSNN
                     Q"
     gene            complement(5634..6926)
                     /gene="lysA"
                     /locus_tag="KRH23_002866"
     CDS             complement(5634..6926)
                     /gene="lysA"
                     /locus_tag="KRH23_002866"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008836 - diaminopimelate decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HHS5226143.1"
                     /translation="MKLHGTMTVNNDELYIGGVSCLELSKKYQTPLYVFDEALVRQNC
                     REYIEYFKAREGKNKVAYAGKAFLPLYMCNLINEEQMCLDVVSGGELYTAYKSNFPME
                     KVFFHGNNKTKEEINMGLDLGVGKFVVDNFYELDLLEALCEDKGKTQEIYFRITPGIE
                     AHTHDYIKTGQIDSKFGFALVNGDLFRAIEKLSEYKNIKLVGLHAHIGSQIFDVEPYI
                     DTVDIMMNLVKEIKEKFNIQLTEIDLGGGVGVYYSEGDKPKTIKEFCETIITKAETSC
                     KELGIEVPTLVIEPGRSIVANAGSTLYTVGSIKDIKDVRVYVSVDGGMTDNVRPSLYQ
                     ASYECSIVNKINHEAMNHVTIAGKCCESGDILIGDINIMDIKSGDILITTSTGAYGYS
                     MSSNYNKIPRAAVVSVFDGNDKIICKRQSYEDLLALEI"
     gene            complement(6944..8137)
                     /locus_tag="KRH23_002867"
     CDS             complement(6944..8137)
                     /locus_tag="KRH23_002867"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004072 - aspartate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HHS5226144.1"
                     /translation="MSIIVQKYGGSSVADTEKIKSIAENIIERRKENPQMVIVVSAMG
                     KSTDEYITLAKELSNEPSKRELDALMSTGEMISASLLSIALNALGCKAISYNAYQLNI
                     KTSGLHGKSQIDDINVNRIKNSLDEGNVVIVTGFQGINEDGDVTTLGRGGSDTSAVAL
                     AVKLNGKCEIYTDVDGIYFTDPRKYSKASKLDEIEYEEMLELASLGAQVMHSRSIELA
                     QKYGVEIYVGRTCGTEKGTYIRGGKDMKLEDKVITGLATSDDDSSITIKDFKAENISS
                     LFEDIATIGISVDMISQTAPILDKISVSFTVPKEELGECKKIVSKYTDEEHVVIDNNI
                     TKFSLVGLGMKNTSGVAAKVFKIFNENGIMIKLITTSEIRITCAINSDDKQVAIEKIA
                     EVFNI"
     regulatory      complement(8219..8387)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00168"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Lysine riboswitch is most abundant in Firmicutes
                     and Gammaproteobacteria where they are found upstream of a
                     number of genes involved in lysine biosynthesis, transport
                     and catabolism; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="lysine"
                     /db_xref="RFAM:RF00168"
     gene            complement(8498..9115)
                     /locus_tag="KRH23_002868"
     CDS             complement(8498..9115)
                     /locus_tag="KRH23_002868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226145.1"
                     /translation="MTNMEKEILLLISRVRCVTESQFRKIYGDQKRYNKKNFKKTLRK
                     MCSEYTLKKYPCDVDYYNYKDLSYVYYLNGSKLFKGDDLIKALVGSELVVRINTAGCD
                     VKRFYRNVSVDDVKYDLFIEYTDQFGNIKQVLVDVDLNNEIDISKYENLSKKIDKSTI
                     PFFKVPNVLVVTPDNLSELNDLERYDNEYSINFIDLGLNKLFNCI"
     gene            complement(9285..10985)
                     /locus_tag="KRH23_002869"
     CDS             complement(9285..10985)
                     /locus_tag="KRH23_002869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226146.1"
                     /translation="MKRYLKTYGVALIIVIIYAFIKLPVLRLDFTSLFSVGIIFFVVA
                     GILDMMLDRNERASKMAKYNFSIAIALLVYIVVVPFITSTPVLHAKSYRELLGKVTES
                     KFTDDISPVSVNDIRLVDEDMAMKLGDKKLGEVPAIGSVSKLGKFHIQNVDGELYWVA
                     PLVHRDIIKWITSLSGTSGYVKVSASNPQDVQLVQEIDGKPIKIVYQPEAYLHQDLQR
                     HLYIHGIVNVGMTDFTLEINDEGRPYWVVSLYEHKIGYGGANATGIATVDAETGKINV
                     YDVKNTPKWVDRIQPQNFITDQIKDWGVYVNGFLNSVISEKGVLVPTEGTSLVYGNDN
                     RSYWYTGITSSGGDESTIGFMLVDSRTKEAKLYKQPGATETAAMKSAEGNVQEKNYEA
                     TFPVMYNILGQPTYVSSLKDKAGLVKRVAFVSVEDYNVLGIGEDKNEALRNYKDALES
                     KGNDLKLDNDLKDEVIEGTVTRISPDVRSGNTNYYVTLDSNKDIIFRATSKVSSELPL
                     TQVGDKVKISYSKEESGVIEMSEFDNLNIANFEDKKEKEKTGTDENTGSQDSENQGNV
                     "
     gene            complement(11382..11945)
                     /locus_tag="KRH23_002870"
     CDS             complement(11382..11945)
                     /locus_tag="KRH23_002870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226147.1"
                     /translation="MNKVYIVTTYTGTILSYLIRNISKKLYTHVSISLNENLKPMYSF
                     GRLNPRNPFIGGFVEENINQGLYAIRKNTVCRVYSLEVDNLQYENLYKNIKLISDYRE
                     DYYYDTMALIYLLMNIQRQSEYKYVCSNFVADMLEKSEIDILNKQAFEVTPNDFYNLS
                     GLTLEYEGLLSEYNSRQHSYVSKIANI"
     gene            complement(12104..12817)
                     /locus_tag="KRH23_002871"
     CDS             complement(12104..12817)
                     /locus_tag="KRH23_002871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2140 domain-containing protein"
                     /protein_id="HHS5226148.1"
                     /translation="MGKVAKILLSLIVIVLVLAGIVVYILTPKERYDVSSQNNKIIDE
                     EYLSKGSYINSMEVVKNPLRMVGKISVSEEEFKNLIYTLMQKHGINELENNFVEMKNG
                     KIKVAGPYKVFGLVNSQYELELRPTLKDGNLVVSLENVKIGKFKLSDKMLEKILSNYN
                     KKVPFEVNGNKITLEKSYLYPVTLKNISIKKGNVDLDMEVEIDLKSQINGALGYLKDS
                     GKVQDILNHLINLKKTSVG"
     gene            13109..14773
                     /locus_tag="KRH23_002872"
     CDS             13109..14773
                     /locus_tag="KRH23_002872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004819 - glutamine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006425 - glutaminyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--tRNA ligase/YqeY domain fusion
                     protein"
                     /protein_id="HHS5226149.1"
                     /translation="MSNETNSSNFIKNIIINDLETGKHDSIITRFPPEPNGYLHIGHA
                     KSICLNFGLAKEFNGKANLRFDDTNPLKEDVEYVESIKEDVKWLGFDWNELNFASNYF
                     DEMYKRALILIKKGKAYVCDLTQEEMREYRGTLTEPGKESPHRNRTIEENLDLFERMK
                     NGEFKDGEKTLRAKIDMSSPNINLRDPIIYRISHSTHHNTGDKWCIYPMYAFAHPIED
                     AIEGITHSICTLEFEDQRPLYDWFVKECEMENIPRQIEFARLNINNTVMSKRKLKQLV
                     DEGIVDGWDDPRVPTISGIRRKGYTAEALRNFCSEIGVSKVNSTVDSQMLDYFLRENL
                     QPKAPLTMGVLRPLKLIITNYPEDKIEMLEIENNAKDESQGKRLVPFSRELYIEQDDF
                     MEEPVKKYFRFFPGNEVRLKGAYFVKCTDVIKDENGNVVEIHGTYDPETKSGSGFTGR
                     KVKSTIHWVDAKSAIPCEFRLFEPLILDDIPENEGKHFLEQINPNSLEILQGFVEPTQ
                     IKDAKPFDKFQFVRNGFFSIDNKYTTDEKFVFNRIVPLKSSFKPGK"
     gene            complement(14880..15779)
                     /locus_tag="KRH23_002873"
     CDS             complement(14880..15779)
                     /locus_tag="KRH23_002873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0001727 - lipid kinase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YegS/Rv2252/BmrU family lipid kinase"
                     /protein_id="HHS5226150.1"
                     /translation="MKKVKLIYNPNSGEKKILSNLDTIIELYQEKNYLLIPYRLTIKE
                     PVKNAFKEVDSSYEHILIAGGDGTVDLVVNAMKELDIKIPIGILPTGTANDFSNALQI
                     SFDIKEAINEIINSKPKKIDIGKVNNKYFINVASAGMFTDVSQRINTDLKNSFGRISY
                     YIKGIEEALYMRKFKIKVSSEEMYYDGDMYLMLIFNGKTAGNINLAYKAEIDDGYLDV
                     IIFKGMPIPKSIPVLISVLRGDYLDQYNGNEILYFKTKKVHIECEDSLITDIDGEKGP
                     DFPLNIECIKDGIEVMGICSEKS"
     gene            complement(15806..16444)
                     /locus_tag="KRH23_002874"
     CDS             complement(15806..16444)
                     /locus_tag="KRH23_002874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate utilization protein"
                     /protein_id="HHS5226151.1"
                     /translation="MDQNLNWLNEKRIEKTIKSLENNNMKGYLVSNKEELLKKIEEIV
                     KAGSLVGCGGSMTLFETGVIDFIREKYNFLDRYAKDIKPEEMKEIYRKSFSADAYFTS
                     TNAITEDGELYNLDGNGNRVAAMIYGPDKVIVIAGVNKIVKDVDEAIKRTKTIAAPAN
                     CKRLSTNTGCKTTGICIDCSSPGRICCSYTLIKRQLTPERIHVIFLNEDFGY"
     gene            complement(16781..17779)
                     /locus_tag="KRH23_002875"
     CDS             complement(16781..17779)
                     /locus_tag="KRH23_002875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4003 domain-containing protein"
                     /protein_id="HHS5226152.1"
                     /translation="MEQSFINGKVNLLIENYKALNEVKGSWQMGLIQHSCALAFTLKN
                     KRISPRLVEERIELIKKNTGLFSNFRGYNMFYMATLLSFESNPESSFKMILDIYKELK
                     SEKFWGDTYLPLTASIVYENREKMDYLTCISKMKIIYDYMRKKHPFLTSSDDYCNIAL
                     IAIHSKNLDEDLEYIEKCYEFLNENGFYKGNDLQALSQILLFSDDRTMLKCKKTIELK
                     KAFKENDCKMNYYGYPIIGAISLLDYREDEIIEEIKNVSNKLKEEKGFGNWSLGKSNR
                     VMISSAIVASIYADLIRNENNIGSITNNIFLNIVVAIQIACVMAATSAAIASSSSN"
     gene            complement(17877..18452)
                     /locus_tag="KRH23_002876"
     CDS             complement(17877..18452)
                     /locus_tag="KRH23_002876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226153.1"
                     /translation="MKLKEALITCVVCSVCLTPLLVNGETKIDADHCKESIVNIDTIV
                     KSGKSFNSKYNQGMEDYKNSDEYKLKVQKEKLQNQLGIKIKKLVPITFEVSYYTSLNQ
                     ENGYGAITATGDDLEDGFVANNHLSFGTKIIVDGKLKTVMDRGSSKYFSNSNAIDVFV
                     PKWSNESESEYYDRVNNMGRHYKKGYIIVEE"
     gene            18768..19031
                     /locus_tag="KRH23_002877"
     CDS             18768..19031
                     /locus_tag="KRH23_002877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226154.1"
                     /translation="MIKNTKQITVEVNEILLQEMSKITNDENNILTDLINESIVNYIL
                     ENKKHNIENKDLEEVIKFYKKENTEKPKSAARAIAEAKTHTLY"
     gene            complement(19468..19845)
                     /locus_tag="KRH23_002878"
     CDS             complement(19468..19845)
                     /locus_tag="KRH23_002878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HHS5226155.1"
                     /translation="MTITKIPPAELKVMKFIWSSDFTVASKDVIEAMEKLYNWKQTTT
                     LTLLSRLVNKQFLSARKIDRHTHYTVLIGEEEYLHFETKTFLDNMHGSSIESFMKSLF
                     KKGVNEEELNSVEKWVKDIKKDE"
     gene            20186..21298
                     /locus_tag="KRH23_002879"
     CDS             20186..21298
                     /locus_tag="KRH23_002879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009009 - site-specific recombinase
                     activity [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HHS5226156.1"
                     /translation="MNAFIRKRNKNYVVYLEFEDEKTGKRKQKNMGTFDKKREASKRL
                     NEVKESLYNDGFLVPSEITVSEFLLDFLNKYSENISLATYNNYVSICKNYINPSIGKY
                     KIQDLHPVHIQNYIDKLSYKLNPQSIKIHINILKLAIKRAYRLKLIKENVMDSIEAPR
                     YKKFKNEIYDREQMIKLLDLAKNTEMELPINLAIGLGLRISEVLGLTWDNIDFEENTI
                     TVNKITSRINGSVILKEPKTESSVRKISSPKELMSLLKEYKIKQNKNLLKSSIRNNNN
                     LLFFNKKCEPIAEDVMSKKFKRFLEKNELPHIRFHDLRHSHVTLLINSKVPIKVISER
                     VGHSNISTTLSVYSHVLKEMDKEASDKISESLFNAN"
     gene            complement(21506..21982)
                     /locus_tag="KRH23_002880"
     CDS             complement(21506..21982)
                     /locus_tag="KRH23_002880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226157.1"
                     /translation="MVKKRLVAVVLSLAMISVGNFSYAHSGGHNSSGGHHNKNKSELT
                     RYYCGGHSAHQHNKGFCPYASTKENSGVTISSVHNEKNHKNYFAEKGYNKGYEDGCKG
                     LYNLSVTEAKSDNLYEKEILKSSYEKGYLIGYNEYKAKKVDDVMKKMLDIPMLASI"
     gene            complement(22181..23806)
                     /locus_tag="KRH23_002881"
     CDS             complement(22181..23806)
                     /locus_tag="KRH23_002881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HHS5226158.1"
                     /translation="MLQVTGVGLRFGDKELFKDVNLKFTKGNCYGIIGANGAGKSTFL
                     KILSGEIEPNTGSISITDKERMSVLKQDHFEYEEETVLNVVIRGHERLWNIMKEKDAL
                     YMKEDFNEEDGIKAAELEGEFAELDGWDAETNAEKILMGLGITKDMHYKQMKELVGGE
                     KVKVLLAQSLFGKPEILLMDEPTNHLDFKSINWLNNFIMDLEESIVIIVSHDRHFLNQ
                     ICTNIVDVDFGKIQMYVGNYDFWYESSQLALQLAKDQNKKTEEKIAQLKEFIARFSSN
                     ASKAKQATSRKKQLEKLEVEDIQPSRRRYPYVGFTPAREIGNEVLEVHNLTKTIDGVK
                     VLDNVSFRLDRDDKVVFMGDEIATTALFNIVMGELEPDSGEYKWGVTTSQDYLPKNHN
                     KFFDGVEYSLVDWLRQFSEEKSESFIRGFLGRMLFSGEEALKEAQVISGGEKVRCMLS
                     KLMLSNANVLVLDDPTNHLDLESITSVNKGLEKFPGVLLFTSHDHEFISTIANRIIEI
                     TPNGIMDRKMDFDEYLESKEIQDQLAKMYGKDK"
     gene            complement(24144..25163)
                     /locus_tag="KRH23_002882"
     CDS             complement(24144..25163)
                     /locus_tag="KRH23_002882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-binding protein"
                     /protein_id="HHS5226159.1"
                     /translation="MKLIKTIDAVGQVLCHDITQIIPGEFKGRKFKKGHIVKEEDIPV
                     LLSLGKDNLYVWEKSEGMVHENEGALFLKELTAGENLDFSEIKEGKIDFIAACDGLLK
                     IDVDALFDLNCVGEIMMATLHNNFIVNKGLKVAGTRVIPLVIDEKKLEDAKKVVGNRK
                     IVNVVPFKPKKVGIVTTGNEVFYSRIVDKFGPVIEEKVKGFGCEVIGQTICPDDKEII
                     KSAIKEFISQGAELICCTGGMSVDPDDVTPTAIKETGADLVTYGSPILPGAMFLLAYY
                     GEVPIMGIPGCAMYHKTTVFDIVLSRVLIDEKLDKYDIARYGHGGLCMNCDVCTYPAC
                     NFAKI"
     gene            complement(25160..25729)
                     /gene="mocA"
                     /locus_tag="KRH23_002883"
     CDS             complement(25160..25729)
                     /gene="mocA"
                     /locus_tag="KRH23_002883"
                     /EC_number="2.7.7.76"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0070567 - cytidylyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0032324 - molybdopterin cofactor
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum cofactor cytidylyltransferase"
                     /protein_id="HHS5226160.1"
                     /translation="MINAVIMASGFARRMGANKLLLNYKGCSIIEHVFREVSKIDFHQ
                     VVVVSQYEEVLLLCNKYGFEYIDNKNANIGQSESIKLGVLNSSKCDGYMFFVGDQPFI
                     DNLYIDKIINTFKLDRDFIVIPRYKDMCGNPVIFPYSKKEELLALKEDEKGKTILKNS
                     SKIKYVEVPKEMLFDIDTKMDYERIGGKL"
BASE COUNT         8627 a         4232 c         2672 g        10362 t
ORIGIN      
        1 tattaaatac taataaaaat ttcctatttt ggggaaaggg agcttaaaac aattttatat
       61 tataaattta tgtttttttt aaaatgcctc tattggtatg tttaagtatt gatttatata
      121 atttatatag ttataatata agatatattg tattattttg gtaaatacat tattacaaaa
      181 gctttatatt ctatgtctta atatttataa aaactttatt ttatttttat aaagtattat
      241 atttctaaaa aagtttccct ttccccaaaa atggctactt aaaaaatcaa gatttcatac
      301 ctaactacta attctatgat ttttaaattt ttcaacttct ttgtcaaagt taaaataaaa
      361 tactaaaaga cacatattat agtgaacaaa aaagatagaa atacatattt taatagaatt
      421 ttaataagat attatatact taaatacaaa taaaattaat tttataattg ttaattaagg
      481 aaatgatatt gtttagagaa ataaaaaaag cactctccat gaatggaaat gctttcttta
      541 ataaattagt tgacgtagta aagatgtatt cagaatacat ctttatgttt tgagtctcga
      601 aatatttatt tgtattattt aaacgaaaat ttatttttta agtgataatc gagtatttac
      661 taataaggct atgattctca atttcatagc cttattaata tacaaacttt actcatacac
      721 agaatatctt ttccaaattt gctctaaatc atcaaaatgc tgtttaatat cttctttttc
      781 cttcatccca acagatatag caagggcatt tgaaatacta agagctggaa ctagagaatc
      841 tacaaatgaa gccatattac tcttaactag aagagtgtta tctgcaagtg atgctactgg
      901 cgcaaataag ctatctgtta atgatattac atgggctcct ttttccttag cataattgac
      961 aatttgataa gatttcttag aataacgagg gaaactaata gcaactatta catcttcttc
     1021 atttattctt acaatctgct caaaagcatc tcccatatcc attctaatta tatgaacatt
     1081 gtcaagtatt atatctaagt aaaaacctaa atattgagct actacaaaag aactcctcat
     1141 tccaagtata tatatttttc tcgctcttaa aagtttatta gaagcttctt taaacgctct
     1201 ctcgtcaatt tcttctagtg tagaccttat attatctata tcacttttta aaactttgtt
     1261 tagtattgca aaatcatcgg aataatcatg tgccatttca actctttgta ctgtagttag
     1321 tttatttttt atgagttctt gaagtgcagc ttgtaattta ggatatccac tataacctaa
     1381 tgcatttgca aatcttacaa ctgtagactc acttactcct acagtttcac ccaatttaca
     1441 tgcagtcata aatgcaactt tatcataatt atttaaaatg tattgtgcta taagtttttg
     1501 acccttactc aatctcgtat attgagattg tatatttgat atcaaatgtt tactgtcctt
     1561 catttcattt gtttcttcca tttttttctc cttttagtta tataaactat tttgttttat
     1621 taacactgtc tttttctcta aaaattttat tttttatctc aatttcatct tagtttttat
     1681 catagcttct taaactcata aaattctaac ttttctgtac cttatacttc acatagtatt
     1741 ttcgattaaa tttattatac catctttcct tgcatttttt aatatttatc caatatttct
     1801 tttaaatttt tcaattttta ctcatttaaa agttatctat cttattttgc atatttagat
     1861 gtatattttg ttttgagaat aagctgttgt atacttatta tttaaagtat ttttaatagg
     1921 tcacactata tatattaact cttaatacaa tcttgtcaag ttttttagta tttattatgc
     1981 ttttttcttt tcaattaaaa tcaattgtgg tgggttattg acttgattta aaaacttaga
     2041 ttctaaaaca ttaaattcat cttgatttaa attattgaca aggttatata tgcaatcttt
     2101 ttcttcttga cctccatcat gccctgtata tatggcaatg cttattactc cattttcttt
     2161 taacatttct aaacttaact ttatagcctt taaagttgta tctggtttgg ttataattga
     2221 atgtttcgct cttggaagat aacccaaatt aaataaaaca catgaaactt cttcttttat
     2281 atattgattc attttttcat gcccatcaaa tatcaatttt actctatctg tatatccttc
     2341 tttctctagt ttctttcttg tagactttat tgcttcttct tgtatatcaa aagcatatac
     2401 aaagcccttt tctccaacct tctcagctag ataccttgta tcatacccat ttcccatagt
     2461 agcatcaatt actatgtcac cttcatttat aatattttct aaataaaatt tatttatatc
     2521 tgtaatttta gttaaatact ttgcatatgc cataatacta tttctcccta ctattaactt
     2581 tatttcattt tttctcaatt tatttttatc ttattttatt gattttaaat attttatttc
     2641 atcttctgtt aggtatctat attctccaac tttggtgtct tttaatacta tttttcccac
     2701 agaaatcctt cttaaattta aaactggatg atttatagct ttgcacattt ttcttacttg
     2761 tctatttcta ccctcatgta tagttatttc acacactgaa taattttttt ctttattttc
     2821 tttagttacc cttattttag caggtgccgt tgtgtaatct tctattttta gtcctgtttc
     2881 gaattgtctt atctcatcat cacttataat tcccttcaca cttgccacat acgttttatc
     2941 aatttcatgt tttggatggg taagcttata tgttaaatcg ccatcattag taagtattaa
     3001 taatccacta gtttcataat ctaatctccc tattggatat actctttccc ttacatcttt
     3061 aagtatgtct attacactgg gtctattgaa ttggtctttt actgtagtta tatatccctc
     3121 tggtttattt aatactatat atatataatt ttcacttggt tttacttttt tattatcaaa
     3181 ttctactatg tctttttctt catcaatatt aaaagataac tcttttacta cacttccatt
     3241 tacctttatt cttcctccaa gaattatttc ttctgctttt cttcttgatg ctattccaca
     3301 agaagctata tacttattaa ttctcatact taatccttcc ttatcttaaa ttatgtgtgt
     3361 ttaatatttt tatcaatgtt aattttgcta cattattata ctatactaga ccttaattaa
     3421 aaacaagcaa aaaaattatt taattttcct aaataattgt aatttctttt cacatactat
     3481 taatatgtaa tagctgacta aacactattt taaggaagtg attattattt caaaggaaaa
     3541 tataaaatat tatttaatag tcgtgtttat tggaatttta ttttttaaat ttattaatac
     3601 tccatcagac tttatatcta gtattgaagg attcttaaag ttttttagcc catttttatt
     3661 agctatttta cttgctttac ttttaaatcc acttgtgatg ctttttgagg taaaattcaa
     3721 agcacataga cttttagcca tttttttatc ttatatattt ataggtttta ttttagcctt
     3781 tgccattagg ttattaattc catcaatagc taatacatta aatagattga taaatgaaat
     3841 gcctatgtat actgattata tagatagttt tatagaaaaa aatatgtcaa acatagattt
     3901 tctaaaaact ttaattcctc atatacaaca tagtttagat aatttattaa aagaagcaag
     3961 taattttgtt ggtaaaattc ctaaaaactt cttaatctat acacttagta tatcttctat
     4021 gctatttaat atgacaatgg gatttatact atctatatac attatatatg acaaagaaaa
     4081 aattgcattg gaatttaaga gatttctata ttcttctact gctagaaaca aggcagataa
     4141 cattatagaa ttttttagga ctactcatga tattttctat gattatttac ttggtagaat
     4201 attagactct cttattattg gtataattgc atttttagga tttcaatttg ttatcagaat
     4261 agaaaatgct ttatttttag cttcaataat attcttaggt aatataattc cctattttgg
     4321 tccttttatt ggtgcaatcc ctccaatagc catgactata ttatatagtc cacaaaaaac
     4381 tatatgggtc attgcatttc tatttatatt gcaacaatta gatggaaatt ttatagaacc
     4441 aaaagttatg ggtaatcaag ttggtatagg agctatatgg gtaatatctg ctattttggt
     4501 gggacaatct ctatttggtt tcataggagt ttttctttca gtaccaatag ctgctgttgt
     4561 aaaaacttat gttgataaat atatagataa tcgtttacaa tagcttttct ctactgtgac
     4621 tttaattttt agtttaaaat ttaactgtta tttattaaat tatttctcaa aaaatatctc
     4681 ttagtaagaa aaaattgcta agagatattt tttataatat ataatttttt cattaaattt
     4741 atgcatatat tttatactta ttgattattt gagttttgag aatttccacc actatctgaa
     4801 ccaccagtag tatcttgtgg agttggtgct ggcgttggat tactattatt tggcttttct
     4861 tgattttgag aagaactgtt attattgtca gacttattac tatctgattt tttatcatta
     4921 tttttagaac tagatttatt atttttacta cttccactat aagaagattt ccttgcatct
     4981 gattcaactc tatacctatc ttctccagcc gtatcttttg cctttttctt tctttgttcc
     5041 tctgcttcgt tttgttcttt ttctaattta gttaactctt ctttcttttt agttgcctct
     5101 tctttaataa cagaggaacc atttttgatt ttctctataa gtttaagttc cttgattgca
     5161 ccctcataat tttttaattc ttcaaactcc gtcatatttg acattctcat agcttgcata
     5221 tacatagctc ttgcattctc attagtacta tcttcttcca gtgcagagga taatgattcc
     5281 atagcttttt tatagttatg tttttctaaa tatgtttttc cttgctctac taaatttatt
     5341 tcatcttttt tattaaatga acatcctaca agaaatatag ataatatcga tattaataaa
     5401 attactcttc ctctcattaa atccctcctt gtcatatact ttaaatttta tcataattat
     5461 aaagttttta aaatatttta tatttattac aagaaatttg ttagtaaaac aaaaaataag
     5521 cagatatgct acgaacgata caataaacca aaaattaatt tagagataca tatcctagca
     5581 aatctgctca taataaactt taatatttaa tttttattat atacttctct attttatatc
     5641 tctaaagcta ataagtcctc atagctttgt ctcttacaaa ttatcttatc atttccatca
     5701 aatactgata ctactgctgc tcttggtatt ttattataat ttgaagacat tgaatatcca
     5761 tatgcaccag ttgatgttgt tataagtata tctccacttt taatatccat tatgtttata
     5821 tctccaatta atatatctcc actctcacaa cattttccag ctattgttac atgattcata
     5881 gcctcatgat taattttatt cacaatacta cactcataac tagcttgata caacgaaggt
     5941 cttacattat ctgtcatacc tccatctaca cttacataaa ccctaacatc ttttatatct
     6001 tttatagaac ctactgtata caatgtactt cctgcatttg caactattga ccttcctggt
     6061 tctattacca atgtaggtac ttctattcca agctctttac atgaagtttc tgctttagtg
     6121 attatggttt cacaaaactc ttttatagtt ttaggtttat ctccttcgct ataataaacg
     6181 ccaactcctc cacctaggtc aatttctgtt agttgtatgt tgaatttttc ttttatttct
     6241 tttaccaagt tcatcattat atccactgta tctatatatg gttctacatc aaatatttgt
     6301 gaacctatat gagcgtgaag acccacaagt ttaatatttt tatattcact taatttttct
     6361 attgctctaa ataaatctcc atttactaaa gcaaatccaa atttagaatc tatctgtcca
     6421 gtttttatat aatcatgtgt atgagcttct ataccaggag ttattctaaa gtatatctct
     6481 tgagttttac ctttatcttc acataatgct tcaagcaaat ctaattcata aaaattatcc
     6541 accacaaatt tacctacacc taaatctaat cccatgttta tttcttcttt agtcttattg
     6601 tttccatgaa agaaaacttt ttccatagga aaatttgatt tataagctgt atataactcg
     6661 cctcctgaaa ctacatctaa acacatttgt tcttcattta taagattaca catgtaaaga
     6721 ggtaaaaaag ctttccctgc ataagcaacc ttattttttc cctctctagc cttaaaatat
     6781 tctatatatt ctctacaatt ttgtctaact aaagcttcat caaatacata aagtggagtt
     6841 tgatattttt tactaagttc taaacaactc actcctccaa tatataattc atcattattt
     6901 acagtcatag ttccatgaag tttcataata gcctccccaa attttatata ttaaatactt
     6961 ctgctatttt ttctatagct acttgcttat catcagaatt tatagcacaa gttatacgaa
     7021 tctctgatgt agttataagt tttatcatta taccattttc attgaatatc ttaaatactt
     7081 tagcagcaac tccagaagta tttttcatac caagacctac taaagaaaat ttagtgatat
     7141 tattatcaat cactacatgt tcttcatctg tatatttaga tactatcttt ttacattctc
     7201 ccaactcttc ttttggaact gtaaatgata cacttatctt atctaaaata ggtgcagttt
     7261 ggcttatcat atctacactt atacctatag ttgctatatc ttcaaataag ctagatatat
     7321 tttcagcttt aaaatctttt attgttatag aactgtcatc atcactagta gctaatcctg
     7381 ttattacttt atcctctaat ttcatgtctt ttccccctct tatatatgtt cctttttctg
     7441 taccacatgt acgtccgaca tagatttcaa caccatattt ttgtgcaagc tctatacttc
     7501 ttgaatgcat tacttgtgct cctaaactcg ctaactcaag catttcttca tattcaatct
     7561 catcaagttt actagccttt gaatattttc ttgggtctgt aaaataaatt ccatcaacat
     7621 ctgtatatat ctcacatttt ccatttaatt taaccgcaag agctacagca gatgtatctg
     7681 aaccacctct tccaagagtg gttacatcac catcttcgtt gattccctga aatccagtta
     7741 ctatcacgac atttccttca tctaaactat ttttaattct gtttacgttt atatcatcaa
     7801 tttgagactt tccatgaaga ccactcgttt ttatatttaa ctgataagca ttataactta
     7861 tagctttaca tccaagtgca tttaatgcta ttgataataa agatgctgaa atcatttcac
     7921 cagtagacat taaagcatct aattccctct tactaggttc attactcaat tcctttgcta
     7981 aagttatata ttcatcagtg gattttccca tggcagacac aactattacc atttgtggat
     8041 tttcttttct tcgttctatt atattttctg ctattgattt tattttttca gtatctgcta
     8101 ctgaacttcc accatatttt tgaacaatta tactcatgct ttctccccct caagctaaat
     8161 tttgataaat aaaaacgccc aaaggtatac tttggacgtg taaatttcat agaccaagta
     8221 accttgtagc tcaccacttt aaaagtgaca gccttatgca tattctgcat aagtccagaa
     8281 aatttgtccg tcaacaaaat ttcttcggct atataccctt tcatcaatta tcaacgctta
     8341 ccagctccta ttgaatacta ttgaatacag ctacctctac cctaggctca ttatttttaa
     8401 ttaatttatt aatatagttt tatcatattc tatataatat tgcaacaatt tttttacaaa
     8461 atgtggcaaa tcgatagttt tcttttctaa agttagctta tatacaatta aatagtttat
     8521 ttaatcctaa atctataaaa tttatgctat actcattatc atatctctct aaatcattta
     8581 attcggatag attatctggt gtaactacca aaacgtttgg tactttaaaa aatggaattg
     8641 tagatttatc tattttttta gaaagatttt catatttaga aatgtctatt tcattattta
     8701 agtcaacatc aactaaaact tgctttatat taccaaattg gtctgtatat tcaataaata
     8761 aatcgtattt cacatcatct acactaacat ttcggtaaaa tctttttaca tcacaacctg
     8821 cagtattgat tctaacaact aattctgatc ctactagagc ctttattaaa tcatctccct
     8881 taaaaagttt actaccgttt aaatagtata cataagagag gtctttataa ttataataat
     8941 ccacatcaca aggatatttt tttagtgtat attcactaca catttttctc aaagtttttt
     9001 taaaattttt tttattgtat cttttttggt ctccataaat ttttctaaat tgagactctg
     9061 taacacatct aaccctgcta attaaaagta atatctcttt ttccatattc gtcatagtac
     9121 attctccttg aagtattatt tgcaaagttg tactaatatt atattaattt tatgacatta
     9181 aatttacaaa gaattaaaat aaaatagcta atttttatag aattaaattc tataaaaatt
     9241 agctattact atgctaaata ctgttatcaa tctttttatt taaattatac attaccttga
     9301 ttttcagaat cttgggaacc tgtattttca tcagttcctg ttttttcttt ttctttttta
     9361 tcttcaaagt ttgcaatatt taggttatca aattctgaca tttctatcac accagattct
     9421 tcttttgaat acgatatttt gactttatca ccaacctgag ttaatggcaa ttcgctagat
     9481 acttttgaag tagccctaaa tattatatct ttatttgaat ctaaagttac ataataatta
     9541 gtgttaccac ttcgtacatc tgggcttatt cttgtcactg tgccttctat tacctcatct
     9601 tttaaatcat tatcaagttt taaatcatta cccttagatt ctaatgcatc tttatagttt
     9661 cttaatgctt cattcttatc ttcacctatt ccaagtacat tataatcttc aacagataca
     9721 aatgcaactc tcttaacaag accagcctta tcttttaatg atgatacata tgttggctga
     9781 cccaatatat tatacattac agggaatgta gcttcataat ttttttcttg aacattacct
     9841 tcagccgatt tcattgcagc cgtttcagta gctcctggtt gtttatataa tttagcctct
     9901 tttgttctag aatcgactaa cataaatcca attgtagatt catctccacc tgaagatgtt
     9961 atacctgtat accaataaga cctattatca tttccataaa ctaatgatgt accttctgtt
    10021 ggtactaaaa ctcccttttc tgatataaca gaatttaaaa atccattaac ataaacaccc
    10081 cagtctttaa tctggtctgt tataaagttt tgtggttgta ttctatctac ccatttaggt
    10141 gtgttcttaa catcataaac atttattttt ccagtttctg catcaacagt ggctattcct
    10201 gtggcatttg ctcctccata gccaatttta tgttcatata aacttacaac ccaataaggt
    10261 cttccttcat catttatttc aagagtgaaa tctgtcatac caacatttac aataccatgt
    10321 atgtataaat gtctttgtaa atcctgatgt aagtaggctt ctggttggta aactatcttt
    10381 attggctttc catctatttc ttgaactaat tggacgtctt gaggattact agctgatact
    10441 tttacataac cacttgtacc acttagagat gttatccatt taattatgtc tctgtgaaca
    10501 agaggcgcta cccagtacaa ctctccatct acattttgta tatgaaattt tcctaatttg
    10561 gatacactcc ctattgcagg aacttctcca agctttttgt cacctaattt cattgccata
    10621 tcttcatcta caagacgaat gtcatttaca ctgacagggc taatgtcatc agtaaattta
    10681 ctttcagtta cttttcccaa tagttctcta tatgattttg catgaagtac aggtgtagaa
    10741 gttataaagg gaactactac aatatacaca agcaaagcta ttgctattga aaaattatat
    10801 ttagccattt tagatgctct ttcatttcta tctaacatca tatctagtat tcctgctaca
    10861 acaaagaaaa ttattcctac tgaaaataaa gatgtaaaat ctaatcttag tacaggtaat
    10921 ttaataaatg cataaattat tacaattatt aatgcaactc catatgtttt aagatatcgt
    10981 ttcatttaat actcctctct aaaaaatgtt attattacta ttatatccat atatttacaa
    11041 aaaataaata tttatcatat ttattatata ttaagatatc tttatatatt tatagttctg
    11101 cttattcaac tatatttaac attatacgtg tatgtataaa tactttttat acactgtttg
    11161 tactatccat cccgcaccta aaggagtggg atttttgcac tattctgtat tatatatatc
    11221 caaaaatatt ataaaaatac aaatattagc agaaatttaa aaactgaaga aagtattcta
    11281 actaagattt acaaattctt aatcctatcg aagttaaact actatcttca gcctaattat
    11341 ctagcaatat ttttttatat gaaaaactct aaatcaagtt tttaaatgtt tgcgattttt
    11401 gatacataag aatgttgtct agaattatat tctgataata aaccttcata ctctaaggtt
    11461 aagccagata aattataaaa atcatttggc gttacttcaa atgcttgttt atttaaaatg
    11521 tctatctcac ttttttctaa catgtcagca acaaaatttg aacatacata tttatattca
    11581 gattgtctct gaatattcat tagtaaatat attaatgcca ttgtatcgta atagtaatct
    11641 tctctataat cactaattaa ttttatattt ttatatagat tttcatattg taaattatct
    11701 acttctaacg aatataccct acacacagtg ttttttctta tagcatataa tccttgattt
    11761 atattttctt caacaaatcc tccaataaat ggattccttg gatttagcct tccaaaagaa
    11821 tacattggtt ttagattttc atttaatgat attgacacat gtgtatacag ctttttactt
    11881 atattcctta ttaagtaaga taatatagtt cctgtatatg ttgttacaat atagacttta
    11941 ttcatcattt ccccccaatc tagtaactaa ataatattat acacttacaa tttaatatca
    12001 taagatattc taacataata aatgtggttt tacaaatttt gattttaagg tactttaata
    12061 ttatataata taataaaaat ataaatataa gttttctata tttttaacca acagatgttt
    12121 tcttcaaatt aatcagatga tttagtatat cttgaacctt tccagagtcc tttaaatatc
    12181 ctaatgcccc atttatttgt gattttaaat ctatttctac ttccatatcc aaatcaacat
    12241 ttcctttttt tatagatata tttttaagtg ttactgggta aagataactt ttttccaaag
    12301 taatcttatt tccattaacc tcaaatggaa cttttttatt gtagttactt aatatttttt
    12361 ctagcatttt atcacttagt ttaaattttc caattttcac attctcaaga cttacaacta
    12421 agtttccatc ctttaaagta ggtctcaatt caagttcata ttgactattt accaaaccaa
    12481 ataccttata tggtcctgct acctttattt taccattttt catttcaaca aaattatttt
    12541 caagttcatt aattccatgc ttctgcatca atgtatatat taaattttta aactcttcct
    12601 ctgaaacaga tatttttcca accattctaa gtggattttt tactacctcc atagaattta
    12661 tatatgagcc ttttgataaa tattcttcat ctatgatttt attattttgt gaactaacat
    12721 catatctttc ttttggtgtc aagatatata caacaattcc tgcaagtact aaaacaataa
    12781 caattaaact taacaaaatc tttgcaacct ttcccataat cgtctccttt acaaatctgt
    12841 catcagattt aaaataaatt tagataacta acttcacata atattcttaa caatatacat
    12901 actataatac agtcttttaa aaattaattc aaccaatcta atgttttgta aataaactgt
    12961 aaaaacatgt ttttagtata aaagttaata ttttgcataa tactcttaat tacaccttta
    13021 tttttttcta atcttggatt aaaattaata ttatgcaata cagtgtagtg ttctgtatta
    13081 taatcaaatt aaataggagg tatagaatat gtcaaatgaa acgaactcat ctaactttat
    13141 aaagaatatt attataaacg acttagaaac aggaaaacat gacagtatca taactcgttt
    13201 tccacctgag ccaaacggat atttacatat tggtcatgca aaaagtatat gtcttaattt
    13261 tggattagct aaggagttta atggaaaagc taatttaaga tttgatgata caaacccatt
    13321 aaaagaggat gttgaatatg tagagtccat aaaagaagat gtaaagtggt taggatttga
    13381 ttggaacgag ttaaattttg catctaacta ctttgatgaa atgtataaga gagctttaat
    13441 actaataaaa aagggtaaag cttatgtatg tgatttgaca caagaggaaa tgagagaata
    13501 tcgtggtact ctaactgaac caggaaaaga aagtcctcat agaaacagaa ctattgaaga
    13561 aaaccttgat ttatttgaaa gaatgaaaaa tggtgaattt aaagatggtg aaaaaacatt
    13621 aagagccaaa atagatatgt cttctccaaa tataaacctt agagacccaa ttatatatag
    13681 aatatctcat tcaacacacc ataatacagg agataaatgg tgcatatatc ctatgtatgc
    13741 ttttgctcat ccaattgaag atgcaattga aggaataact cactctatat gtactttaga
    13801 gtttgaagac caaagacctc tttatgattg gtttgttaaa gaatgtgaga tggaaaatat
    13861 acctagacaa atagaatttg ctagacttaa tataaataat actgtcatga gtaaaaggaa
    13921 attaaaacaa cttgtagatg agggtattgt tgatggttgg gatgaccctc gtgttcctac
    13981 aatatccgga atcagacgta agggatatac tgcagaagca ttgcgcaatt tctgtagtga
    14041 aataggggta tcaaaagtta actctacggt agatagtcaa atgcttgatt atttcctaag
    14101 agaaaactta caaccaaagg ctcctcttac tatgggagtt ttaagacctt taaaacttat
    14161 tataactaat tacccagaag ataagattga gatgcttgaa atagagaata atgctaaaga
    14221 tgaatctcaa ggaaagagat tagttccttt ctctagagaa ttgtatatag aacaagatga
    14281 ttttatggaa gaacctgtta agaaatattt tagatttttc ccaggaaatg aagtccgttt
    14341 aaaaggtgct tattttgtaa aatgtactga tgtaattaag gatgaaaatg gaaatgtagt
    14401 tgaaatacat ggtacttatg accctgaaac taagagtggc tctggcttta caggacgtaa
    14461 ggtaaaatct acaatacatt gggttgatgc taaatcagct ataccatgtg aatttagatt
    14521 atttgaacca ttaattcttg atgatatacc tgaaaatgaa ggtaaacatt tcttagaaca
    14581 aataaatcct aattcattgg aaatattaca aggttttgtt gaacctacac agataaaaga
    14641 tgctaaacct tttgataaat tccagtttgt tagaaatgga ttctttagta tagataataa
    14701 atatacaact gatgaaaaat ttgtatttaa tagaatagtt cctctaaaaa gttcttttaa
    14761 accaggtaaa taatcttaca atcaaaaaat gaagacttaa aatataaatt acttctacta
    14821 taaataaact tagttagaag taatttttta tttgagtctt catcatttac tttaaatgat
    14881 taactttttt cactacagat tcccatgact tctattccat cttttatgca ttctatgtta
    14941 agaggaaaat ctggtccttt ttctccgtca atatctgtta taagtgaatc ttcacattct
    15001 atatgcacct ttttagtttt aaagtatagt atttcatttc cattatattg atctaaataa
    15061 tcacctctaa gcacacttat caaaactggt attgattttg gtattggcat tcctttaaaa
    15121 ataattacat ccaaatatcc atcatctatt tcagccttat atgctagatt tatatttcct
    15181 gctgttttgc cattaaaaat caacataaga tacatatctc catcataata catttcctca
    15241 gaagatactt ttatcttaaa tttcctcata tacaatgctt cttctattcc ctttatataa
    15301 taagaaattc ttccaaatga attttttaag tctgtgttta tcctttgtga tacatccgta
    15361 aacataccag cacttgcaac atttataaag tacttattat tgactttccc tatgtctatt
    15421 ttctttggtt ttgaatttat gatttcattt atagcttctt ttatatcaaa tgaaatttga
    15481 agagcatttg aaaaatcatt tgcagttcct gtaggcaaaa ttccaattgg aatttttatg
    15541 tctaattctt tcattgcatt tactactaaa tctacagtac catcaccacc agctatcaat
    15601 atgtgttcat aagaactatc aacttcctta aatgcattct ttacaggttc tttaatagtt
    15661 aatctatagg gtatcaataa ataatttttt tcttgatata attctatgat agtgtctaaa
    15721 tttgataata tctttttttc acctgaatta ggattgtata taagttttac ttttttcatt
    15781 atttctcctt actcatttta ttcttttagt atccaaaatc ttcatttaaa aaaatcacat
    15841 gtattctttc tggtgttaat tgtcttttta taagtgtata actacagcat attcttcctg
    15901 gacttgaaca gtctatacat ataccagtag tcttacatcc agtatttgta cttaatcttt
    15961 tacaattggc tggagcagct attgtttttg ttctttttat agcttcatct acatctttaa
    16021 ctattttatt tactcctgct ataactatta ctttatcagg tccatatatc atagcagcaa
    16081 ctctattccc attcccatct aaattgtaaa gttctccatc ctctgttatt gcattagtac
    16141 ttgtaaaata agcatctgca gaaaatgact ttctatatat ttctttcatt tcttctggtt
    16201 tgatatcttt tgcatatcta tcaagaaaat tatatttttc tcttataaaa tcaatcactc
    16261 ctgtttcaaa taaggtcata gaacctccac atcctactag agaacctgct ttaactattt
    16321 cttcaatttt tttaagaagc tcttctttgt tacttactaa ataccctttc atattattgt
    16381 tttccaaaga ttttattgtt ttttctattc ttttttcatt aagccaattt aaattttgat
    16441 ccattttaac ttccccctta tttttaatat gtacttaatt atttataaac tttattttct
    16501 ttataagttt attttagtac atctaaaaaa aaatacaata taaaacttaa atagttttac
    16561 ataatttttt ccaaaataac ttactcaatc aaaaaaggaa agtagatgta ctattctact
    16621 ttccctatat tgtatgtagt atttattgcc taaaatctat atattaatta tatgtttcat
    16681 attatataat atcacagtta attaaaatgt aatactatct tctttttaaa catataaatt
    16741 gtattattaa atttaatata tccaacttca ataaatctta ttaatttgat gaagaagatg
    16801 ctatagctgc acttgttgct gccattacac atgcaatttg aatagcaaca acaatattta
    16861 aaaatatatt attagttata gagcctatat tattctcatt tcgtatcaaa tctgcataaa
    16921 ttgaagctac aatagcagaa ctaatcatta ctctattact ttttcctaaa gaccaatttc
    16981 caaagccttt ttcttcttta agtttatttg aaacattttt tatctcttct attatttcat
    17041 cttctctata atctaataat gaaattgctc ctattattgg atatccataa taattcattt
    17101 tacaatcatt ttctttaaat gcttttttaa gttcaatagt ctttttacat ttaagcatag
    17161 ttctatcatc actaaataaa agaatttggg ataatgcttg taaatcattt cctttataaa
    17221 aaccattttc atttagaaat tcataacatt tttctatgta ttctaaatct tcatctaaat
    17281 tttttgaatg aattgcaata agtgctatat tacaatagtc atcactagaa gttagaaatg
    17341 gatgtttttt cctcatgtaa tcatatatta ttttcatttt tgatatacat gtaagataat
    17401 ccattttctc tctattttca taaactattg atgctgtaag tggtaaatat gtatcgcccc
    17461 aaaacttttc acttttaagt tctttgtata tatctaaaat catcttaaaa ctactttctg
    17521 gatttgattc aaacgaaagt agtgttgcca tataaaacat attatatcct ctaaaattag
    17581 agaataatcc agtatttttt ttaataagct ctattcgttc ttccactaat ctaggactta
    17641 ttctcttgtt cttaagggta aatgcaagtg cacaactatg ttgtatcaat cccatttgcc
    17701 aagaaccttt aacttcattt aatgctttgt aattttctat taataagttt acttttccat
    17761 ttataaacga ttgttccata ttgccctcct agtaatatat ctcattgtac taatagtttt
    17821 atatttatta tatatatatt aaatactaca atcaatacat attacttcaa agaacatcat
    17881 tcttcaacaa taatgtagcc ttttttgtaa tgtcttccca tattattgac tctatcatag
    17941 tactctgatt cactttcatt actccatttg ggcacaaata catctattgc attagaatta
    18001 ctaaaatact tactagaccc cctatccata acagttttta attttccatc tacaataatc
    18061 ttagttccaa aacttaagtg attgtttgct acaaaaccat cttctaaatc atctcctgta
    18121 gcagttatcg ctccatatcc attttcttga ttaagacttg tgtaataact aacttcaaaa
    18181 gttataggta ctaacttctt tattttaata cctaactgat tttgtagttt ctccttttgt
    18241 actttcaact tatactcatc actattttta taatcttcca taccttgatt atacttggaa
    18301 ttaaagcttt tacctgactt tactatagta tctatattta ctatagattc tttacaatga
    18361 tctgcatcta tttttgtttc tccatttacc aataatggag ttaaacatac actacataca
    18421 acacatgtaa tcaatgcttc tttaagcttc ataaattccc cccttattat tttgatatat
    18481 tagcatattt aatattatat gtctacattt agatttaaat accacaccca tttgctttaa
    18541 gaagttgtct tatatttaat tcaccttaaa cacttataaa tcctctatct tagaatcata
    18601 tagaataaag cttttatctt taaatatttt ttattaatct tttaaaatct aaaactactt
    18661 tatctaattt tctctttttt agaatttaag aattaaaatt ctataatttt aaaacatatt
    18721 gaatttattt ttttgagatg atataatttt cttaagaggt ggttgatatg ataaaaaata
    18781 caaaacaaat tacagtagaa gttaatgaaa ttttattaca agaaatgtct aagataacta
    18841 atgacgaaaa taatattttg acagatttga taaatgaatc aattgtaaat tatattcttg
    18901 aaaacaaaaa acataatatt gaaaataaag atttagaaga agtgattaaa ttttacaaaa
    18961 aagaaaatac tgaaaaacct aaaagtgcag caagagctat agctgaagca aaaactcata
    19021 ctctgtatta atcaaataaa aaagttccta aaaactagga acttttttat attaataatt
    19081 attaatatat ctcaatattt atctcaaatc tatcaatata agcatgttta atacaatcta
    19141 ttgtatactt atcttaccct agaaataatc aaaacaaaaa taaaattatg ccctttatat
    19201 ctaaaacaat taatttacat gattaatata caaaaattct gacttttaaa ttcgtataca
    19261 atatcaaact aaaataatat taatgacaaa cccaatataa attaaattca aacaggtttg
    19321 attttacatc aaacttattg tattaatatt aaataacaag acaaaaatat ttataaaaat
    19381 cacaaatttt acataaaact ttatatttga ttcatttaac taattattgt aaaaactatt
    19441 tattttatga taattaacta caccaaatta ttcatctttt ttaatatcct taacccattt
    19501 ttcaacagag ttcaattctt cttcatttac cccctttttg aacaaggatt tcataaaact
    19561 ctcaatagaa cttccatgca tattatctaa aaaagttttt gtttcaaaat gtaaatactc
    19621 ttcttctcca ataagaactg tataatgtgt atgtctatca atttttcttg cacttaagaa
    19681 ttgcttattt actaatcttg ataaaagtgt tagtgttgta gtttgcttcc aattatatag
    19741 tttttccata gcttcaatga catcttttga tgctactgta aaatctgaac tccaaataaa
    19801 tttcatgact tttaattctg ctggtggtat cttagtaata gtcatatgat tttacactcc
    19861 tctcaaactt ctacataatt aaatactata ttaatagact tttcgagtca aaggttttat
    19921 ttaaaatatc tcatccaaat ttattaatac aaaaaattta tatttttatt caaaattaaa
    19981 cacacaatct attaatataa agataaatat ctattctata agtataacag attatcaaat
    20041 taaaattcta atatttgaca taatatatac attttttaaa taaatatata caatgtatta
    20101 aaatgtatgc aactctattt caaaattatt ttgtgatata tatatgttat aataaatgta
    20161 taaaattttg attggtgggt tatatatgaa tgcatttatt agaaaaagaa ataaaaacta
    20221 tgttgtttac ctggaatttg aagatgaaaa gacaggtaaa agaaaacaaa aaaatatggg
    20281 tacttttgat aaaaaaaggg aagcaagtaa aagactaaat gaggtaaaag aaagcttata
    20341 taatgatggt tttttagtac caagcgaaat tacagtgtca gaatttctat tagattttct
    20401 aaataaatat agtgaaaata tatctttagc tacatataat aattatgtta gtatttgtaa
    20461 gaattacatt aatccatcta ttggaaaata taaaatacaa gacttacatc cggttcacat
    20521 acaaaactac atagataaac tatcttataa actaaatcct caatcaatta agattcatat
    20581 aaatatattg aaacttgcaa taaaaagagc ttatagactc aaattaataa aagaaaatgt
    20641 tatggatagt atagaggctc caagatataa aaaatttaaa aatgagattt atgatagaga
    20701 acaaatgata aaattattag atttagcaaa aaatacagaa atggaattac ctattaattt
    20761 ggctattgga ttaggtctta gaatttcaga agttttaggt ctaacttggg ataatattga
    20821 ttttgaagaa aatacaataa cagtaaataa gataacttcc cgaattaatg gttctgttat
    20881 tctcaaagag ccaaagacag aaagctctgt tagaaaaata tcttctccca aagaattaat
    20941 gtctttatta aaagaatata aaataaaaca gaataaaaat ttattaaaat cttccattag
    21001 aaataataat aatttgttgt ttttcaataa gaaatgtgaa cctattgctg aagatgttat
    21061 gagtaaaaaa tttaaaagat ttttagaaaa gaatgaatta cctcatatta gattccatga
    21121 tttaagacac tcacatgtta ctttacttat aaattctaaa gtacctataa aggttatatc
    21181 cgagagagta ggacactcaa atataagtac tactctaagc gtttattctc atgtacttaa
    21241 agaaatggat aaagaggctt ctgacaaaat ttctgaaagt ttatttaatg ctaattaata
    21301 ttaatttatc ttagctttaa attagcttag cttattgaga tagattcatt aatattaaat
    21361 gtatctatct caaattaata actacttaaa taatctgttt tattttaatt tatcacctca
    21421 gttattatac ttttttacga aaaattatac tttacaataa aaaagatatt cccttataga
    21481 aaatatcttt ttaaatacta tattattata tacttgctaa cattggaata tctaacatct
    21541 tcttcattac atcatctact ttttttgctt tatattcatt gtatccaatt aaatatcctt
    21601 tttcatatga actttttaaa atctcttttt catataaatt atcagatttg gcttctgtga
    21661 cacttaaatt ataaagccct ttacacccat cttcataacc tttattatac cctttttctg
    21721 caaaatagtt tttatgattt ttttcattat gtactgaaga tattgttact ccagaatttt
    21781 cttttgtact agcataagga caaaaacctt tattgtgttg atgtgctgaa tgtcctccac
    21841 aataataacg tgttaactct gatttatttt tattatgatg acctcctgat gaattatgcc
    21901 ctcctgagtg agcatatgaa aaattcccta cactaatcat agctaaactc aatactacag
    21961 ctactaacct tttcttaacc ataatctatt ccccccaaaa tgttatatat ttttattata
    22021 tcatctacta tattatattt aaattcttaa tatacaaaat attactctat tctgctaata
    22081 aacatgttta aacaacataa aaaacctcct aatatttgat taaaaattta cacactcatg
    22141 catagcatgt ctcaaatatt aaaaggtttt atactaataa ttatttatct tttccataca
    22201 ttttagctaa ttggtcttgt atctctttac tttctaaata ctcatcaaag tccatttttc
    22261 tatccattat tccatttgga gttatctcta taattctatt tgctatagta gatataaatt
    22321 catggtcatg agaagtaaat aaaagcactc ctgggaactt ttcaagtcct ttatttacag
    22381 aagttatact ttctaggtct aagtggttag tagggtcatc taatacaagt acatttgcat
    22441 ttgaaagcat tagcttacta agcatacatc taaccttttc tcctccagat ataacttgag
    22501 cttcttttaa tgcttcttca cctgagaata acattctacc taaaaatcct cttataaaac
    22561 tttcactttt ttcttcagag aactgtctaa gccagtcaac caaagaatat tctactccgt
    22621 caaaaaactt attatgattt tttggaagat aatcttgaga agtagttact ccccatttat
    22681 actctccact gtctggttca agttctccca taactatgtt gaaaagtgca gtagtagcta
    22741 tttcatctcc cataaatact actttatcat ctctatccaa tctaaatgac acattatcaa
    22801 gaaccttaac cccatctata gttttagtta aattgtgtac ttctaaaact tcattcccaa
    22861 tttctcttgc aggtgtaaat cctacatatg gatatcttct tcttgatggt tgtatatctt
    22921 caacttctaa tttctctaac tgtttctttc ttgatgttgc ttgtttagcc tttgaagcat
    22981 tagaactaaa tctagctata aattccttta attgagctat cttttcttca gtctttttat
    23041 tttggtcctt agccaattgt aaagccaatt gacttgactc ataccagaaa tcatagtttc
    23101 caacgtacat ttgtatttta ccaaaatcta cgtcaactat attagtacat atttgattta
    23161 ggaaatgtct atcatgtgat actattataa ctatagattc ttctaaatcc attataaaat
    23221 tatttaacca gtttattgat ttaaaatcta agtggtttgt aggttcgtcc attaatagta
    23281 tttcaggctt accaaaaagt gattgtgcta acaatacctt aaccttttcc ccaccaacta
    23341 gttccttcat ttgtttgtaa tgcatatctt tcgttatgcc aagacccata agtattttct
    23401 cagcattagt ttctgcatcc catccgtcaa gctctgcaaa ctcaccttca agttcggcag
    23461 cttttatccc atcttcttca ttaaagtctt ccttcatata caatgcatct ttttctttca
    23521 ttatgttcca aagtctctca tgacctctta taacaacatt taaaacagtt tcttcttcat
    23581 attcaaagtg gtcctgtttt aaaactgaca ttctttcttt atcagttata gatatactac
    23641 ctgtattagg ctctatttct cctgataata tttttaaaaa agtagatttt cccgcaccat
    23701 tagctcctat tattccatag caattacctt tagtgaattt taagttaaca tctttaaata
    23761 gttccttatc accaaatcta agtccaacac ctgtaacttg taacattaat atattttcct
    23821 ttctttttgc tcataattta ttttatcata aaactttgat aacattttta ttatatatta
    23881 tcacgtaaat agtatatttt ttatactaaa tttgtgaaat atttattaaa ataatactaa
    23941 aaattgtaaa tttataaaaa ttaacaatct cttatattat acttataaag aaatcaaatt
    24001 gcaactttat tcattctttt acacattgaa aataagttat tataatttct aaataaatat
    24061 gcttttttta aaacatcatt ctagctgttt tgtttcatat ttaaaaagag tacttaattt
    24121 gtaaatactc ttttttaata actttatatt ttagcaaaat tacatgcagg ataagtacat
    24181 acatcacagt tcatacaaag gccaccatga ccatatctag ctatatcata cttatcaagc
    24241 ttttcatcaa ttaaaaccct agataaaact atatcaaata ctgtagtttt gtgatacatt
    24301 gcgcatcctg gtatacccat aattggaact tctccataat aagcaagtaa aaacatagct
    24361 cctggtaata ttggtgaacc atatgtcact aaatcagctc cagtttcttt tatagctgtt
    24421 ggtgtaacat catctgggtc tacactcatc ccaccagtac aacagataag ttctgctcct
    24481 tgacttataa attcttttat tgcactcttt ataatctctt tatcatctgg gcatatagtc
    24541 tgtcctataa cttcacaacc aaagcctttt actttttctt ctattactgg tccaaattta
    24601 tcaacaattc tgctataaaa cacttcattt cctgtagtaa caattcctac tttcttaggt
    24661 ttaaaaggta ctacatttac tatttttcta ttaccaacta ctttttttgc atcttctaat
    24721 tttttctcat ctataactaa aggtatcact cttgttccag ctacttttaa acctttattt
    24781 actataaaat tattatgaag agtagccatc attatttctc caacacaatt caaatcaaaa
    24841 agtgcatcaa catctatctt taatagacca tcacatgctg ctataaaatc tattttccct
    24901 tcttttattt cactaaaatc taaattttct ccagcagtta gttcttttaa aaacaatgcg
    24961 ccttcatttt catgaaccat tccttctgac ttttcccata catacaaatt atctttacca
    25021 agagataata acactggaat atcttcttct tttactatgt ggcccttttt aaattttctt
    25081 cctttaaatt ctccaggtat tatttgagtt atgtcgtgac ataaaacttg tccaacagca
    25141 tctatagttt ttattagctt cataatttac ccccaattct ctcataatcc atttttgtat
    25201 cgatatcaaa taacatttct ttaggaactt ctacatactt tatttttgat gaatttttta
    25261 aaatggtctt acctttttca tcttctttaa gtgccaacaa ttcttctttc ttactatatg
    25321 ggaatatgac tggatttcca cacatatctt tgtatcttgg aattactata aaatctctat
    25381 ctaatttaaa agtatttata attttatcta tatataagtt atcaataaat ggctggtctc
    25441 ctacaaagaa catataacca tcacattttg agctatttaa aactcctaat tttatagatt
    25501 cactttgacc tatatttgca tttttattat ctatatattc aaaaccatat ttattacaca
    25561 ataacaaaac ctcttcatat tgacttacta ctacaacttg atgaaaatca atcttgctaa
    25621 cttctctaaa tacatgttct attatagaac agcctttata atttaataaa agtttatttg
    25681 ctcccattct tctggcaaag cctgatgcca ttatcactgc atttatcata tatatcatcc
    25741 ttggtattta taatatattg atagttctat gatttttata atatctctat tgatattatc
    25801 tatatatata atatcatata aactatttta atacttcaat atcttacaca aaatttttgt
    25861 tttaagcttc cataaaatat ctctatttca ctt
//
LOCUS       DAEORM030000053        25646 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.053, whole genome shotgun sequence.
ACCESSION   DAEORM030000053 DAEORM030000000
VERSION     DAEORM030000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 25646)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25646)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 25646)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25646
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.053"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            complement(<1..1016)
                     /locus_tag="KRH23_002884"
     CDS             complement(<1..1016)
                     /locus_tag="KRH23_002884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004527 - exonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease domain-containing protein"
                     /protein_id="HHS5226161.1"
                     /translation="MKRVYIDFEMNMPNSKSKRAVFNSDIIAIGAVMYDEKTKNIDKF
                     KSLIRPVSNEELYPHIQELTHISSEELKSAPSYEEVMRKFKKWLGIFSDIKGIYTFGN
                     LDLTCFNNTDMRSAKKNNHPRFVNNIRDLFVDIKEKYINCGMRCMNYISLKNLLEFVN
                     LEFSGDAHDPLNDAYNLFILDEAITNNVDIQNLLIIRDIIRPPFNDINSNLDNCFNKF
                     KESLYKKEGNYNIVDFSVEIIKTVRMYLLTIIDVNIQNLEIMKDISKKMDTIDKLKDI
                     EEGYFYLLEDVYFDMKDVLEDLMLYRMNEDEYKYEIKNIIKMFDEDLDNEKIYINKCN
                     NLNVV"
     gene            complement(1064..1924)
                     /locus_tag="KRH23_002885"
     CDS             complement(1064..1924)
                     /locus_tag="KRH23_002885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiocytidine(32) synthetase TtcA"
                     /protein_id="HHS5226162.1"
                     /translation="MSELSGKGCEIIVPFEERLPVRDIEKSIIKKYRKNLWSKFMKAI
                     RDYKLVEEGDKIAVAISGGKDSILMAKMFQELKKHGQVNFDVEFIAMDPGYHANIRQL
                     LIDNCEYLNIPIHLFDSRIFEIADEIAKDYPCYMCARMRRGALYSKAEELGCNKLALG
                     HHYDDVIETTMLNLLCAGNFKTMLPKLNSTNFEGIKIIRPLYYIREEHIIRFIQNSGI
                     WPLNCACMVAAKKTGNKRYEIKDLIKSLESNFKNVEKSIFKAAENVNLDSVLGWQKDG
                     EKHSFLENFE"
     gene            2193..2402
                     /locus_tag="KRH23_002886"
     CDS             2193..2402
                     /locus_tag="KRH23_002886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat associated protein CotJA"
                     /protein_id="HHS5226163.1"
                     /translation="MENKTRDIKKNCGPSLARPYINNQIFTEMYCLSDALKFGTIFPE
                     LNLLESEMYNKELYAKPKKYRGGRR"
     gene            2402..2668
                     /locus_tag="KRH23_002887"
     CDS             2402..2668
                     /locus_tag="KRH23_002887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat protein CotJB"
                     /protein_id="HHS5226164.1"
                     /translation="MKDSSRAELMRKVQETSFACVDMNLYLDNHPDDKNAINTYNSLC
                     NQFAQARYAYENKYGPLTNFGYAPSRCPWQWADQPWPWDREFNY"
     gene            2697..3269
                     /locus_tag="KRH23_002888"
     CDS             2697..3269
                     /locus_tag="KRH23_002888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HHS5226165.1"
                     /translation="MWIYQKTIQHPVNIKTCDPRMAKFLITQFGGPNGELAASLRYLS
                     QRYTMPTGNMRALLTDIGTEELAHVELICTMVYQLTSDASPEELKAAGLGSNYAQNGY
                     GIYPTDSNGVPFDVRPIAVMSNPVTDLHEDMAAEQKALATYYQLINLTDDVDVIDVLK
                     FLGQREIIHYQRFGEALMDAYELEESQKMF"
     gene            complement(3504..4694)
                     /locus_tag="KRH23_002889"
     CDS             complement(3504..4694)
                     /locus_tag="KRH23_002889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HHS5226166.1"
                     /translation="MNFNQKRIAASIMATAIIMPTMGNLAYANESEVESVSIESRTIT
                     GNAVNFRKGPGTNHESMGKLYKGDKVEYVGKEGSWVKVKYNGNTGYVHGNYVAINSLG
                     SSNESSDTSVKSTKVVTAKGLNFRTGPSTSSSKISTLGYGTEVGYISESNGWSKISSN
                     GRVGYVSSKYLGTSVNDSTNENAENSSNDLVKGTKVVTAKSLNVRTGPGTSHSKIATL
                     SYGTEVGSISESGGWTKVSYGNQTGYVSSQYLAEKGSVDTSIPSYSTNSPSQGADSVI
                     SFAKTLLGKPYVWGAEGPNSFDCSGFTQYVMKKSVGVSIPRVSRDQSKYGTYVNRGDL
                     RSGDLVFFDTQGSNNGSVSHVGIYIGNGDMIHASSGSSKKVTISNINSSYYSSRYVNA
                     RRVL"
     gene            complement(4954..5385)
                     /gene="dut"
                     /locus_tag="KRH23_002890"
     CDS             complement(4954..5385)
                     /gene="dut"
                     /locus_tag="KRH23_002890"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004170 - dUTP diphosphatase activity
                     [Evidence IEA];
                     GO_process: GO:0006226 - dUMP biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0046081 - dUTP catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HHS5226167.1"
                     /translation="MYNLKVKKLNDDAIIPNFAHKGDAGMDLYSIEEVVIPPGETKLI
                     KTGICIELPTMTEAQVRPRSGLALKHSVTVLNTPGTIDEGYRGELKIILINHGKNDFK
                     VEKHMKIAQMIVKPIYDINIEEVKELSDSERGKGGFGSTGF"
     gene            5498..7726
                     /locus_tag="KRH23_002891"
     CDS             5498..7726
                     /locus_tag="KRH23_002891"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type IA DNA topoisomerase"
                     /protein_id="HHS5226168.1"
                     /translation="MKLVLAEKPSVAKTIASFLGAKTRQDGYFEGNDYIITYAVGHLV
                     SLYDMKDYDKDKYSGSWKMNNFPFVPEDKFKFKIDSSKTKQFNTVKKLLNRKDVEYVI
                     NATDNDREGELIAFLIFLLAKNKKPVKRILVNEWTPEDITRGIKNLKDEDEMRNLQAA
                     GYTRLITDWLIGINFTSVATLKYGNGKLLNIGRVILPTVKLVYDRDMEILNFVPKTYY
                     EIEGHFKAEAGEYKGKYVKGKESKFDTLEDANKIIASITSETGKILDKKVTMSKEYAP
                     KLFSLTSLQGYITSKYSNFTSDKVLNVCQSLYEGNGKGGYITYPRTDSIFLEESLASK
                     ASQTLDKLKVGLEYENKIKFSKTKRVFDSSKVDSHSAIIPTYIIPKSLSKDEQLVYDA
                     IKDRFVANFMPPAEYENTEIKTEVDNCTFLTKGKVLKSKGYLEVYNKEEKNDLLPLVN
                     KDDVVDVLEIKPLTKQTTPPKPYTEDTLLKAMKNCGKNVPEEDTTVLSGYSIGTSATR
                     ADVLKKISQVGYVKKKGKSYSITDLGKNLVEIFPVKDLFDVDYTGKLEKSLSDIQKGK
                     YTRKEYLTNIISFIYQNVNIIKQDASKNINTEAYTFDSKTKKFTKTKEKKQKKDVTNT
                     EKEVAISKDSNNKKEVKNGDENQSLGKCPICQGDVLEFDKGFACKNHKECKFVIWKND
                     KYLSLYKKKVNKTMVKNILKKGETKVKSLTAKNGNKFDATLKYDKNPDTGYFNWKIEF
                     DN"
     gene            complement(7837..8322)
                     /locus_tag="KRH23_002892"
     CDS             complement(7837..8322)
                     /locus_tag="KRH23_002892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HHS5226169.1"
                     /translation="MDNNNILKIADSFLDFLFVLENNIFKESDLLKKFQNNSDIMKAY
                     FEECPMAPSHAKVILYLMTSNSSSISQIASNLGILKSNMTPIIDRLVEHGLVNKFPDP
                     KDRRILRVELTDKAFKLFDAVKAILKESLVKKLSNLSEEELTLLDEHTLKLSEIVKKL
                     G"
     gene            8574..9797
                     /locus_tag="KRH23_002893"
     CDS             8574..9797
                     /locus_tag="KRH23_002893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_function: GO:0042802 - identical protein binding
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HHS5226170.1"
                     /translation="MKRYLIVFLMCSSLFLVGCGKTEESEPEKPIAVSVQKAVGGEIE
                     NTNSFSGTTKVKDETAVTAQTVGTVQEVYVKLGQNVRKGDELLSISSPELENSVKQSK
                     ASLDLAKASYSSATGGSLEAQVNQAKTALDNAKIQYEESQRNYDNNKILYEQEVISLD
                     QFKKIEFSLEQTKQQLDSAQRAYDTATSKSIPQAKALAKKQLDQAQVSYNLAMSNLDK
                     LTLTSPVDGTITAKNFDSKEMITQSQPAFIISNPNILEVDLNVAESDIGKFKKDGNVD
                     VIIEDQRILGKIDYVPSVVDPQTSLYPVKVLVNNTNNKFKAGMSAQVNLSVEKENGAV
                     TVPKKAIFEENGKKYVYIATKDNIAKKHLVQTGIVTEDKIEIKSGVSDKDTVIIGGIS
                     LISDGTKIFPVEKEK"
     gene            9801..12935
                     /locus_tag="KRH23_002894"
     CDS             9801..12935
                     /locus_tag="KRH23_002894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0042908 - xenobiotic transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter permease subunit"
                     /protein_id="HHS5226171.1"
                     /translation="MNLTQTSVKRPLTIIMVFLVLIVFGGIGYKKMSINLMPDIEIPV
                     VMVMTTWTGAGPQDVDEQVSQKVDESLSAVSNVKSTISSSQESVSMVVAQFEFGTNLD
                     EIMNDVRSKVDALQTILPDDAAKPTVLKLDMNAQAIGQLVISGGNENSSQALRKYAED
                     VIQPKIESIDGVTSADLKGGKKAQVNVIADPAVLSNYGVSLSTIKGVLSSSNKTFPYG
                     SITQGEDKIVLRAIDKLESLDDIKQIQIPVKGGNTVRLDNLCSVDYGYADKDSIYRYN
                     GKDSLVIDISKQQDANTVKVMQSAYKYVDELNKENPQFKIKIANDTSSYISESINSVM
                     SNLLISAVIAFIVIFAFLKSVRASLVVAVAIPISIIGAIAILYFTGESLNLITASSLV
                     ISVGMVVDNATVVIENIFKYRKSGRLSLDDCAIEGTRTVTNAILASTLTTIAIFLPIM
                     FTEGIAKITFGALGKTLIASLAFSFIGAITLVPSVFAKLSRGKNSQKMQEKDSPIFDK
                     VSEAYKKLLSVCLRHQRLVVISSLLIFVASLFGMGFIGMDFMPAADKGELSISIELPK
                     GLSLESNDYYVSMTEKKVSDIPEIKTLITTLTSDSNNSKASIAIELESQKNRKRTTDE
                     IEKEIIDRVATVPDCKINVSQNSSVMGGAGGADFTLEMKGPDLDVLKILGKEAEKEFS
                     SIKGFRNVETSLTDTTQEAQFTIDKHKAQEYGVNTAEIAGMLRTAINGDSVTTATIDD
                     YKVDVNLKFKADTIDSLEDIKQLKVNSATGKEVPLGAFSDIKMADGLQSISRTDGDFS
                     VNITATLDNLDAGTATKLALEKTNKMVIPKDYSIGVGGETEMMNESMASLGFSMVIAI
                     ALVYMVMVAQFESFSKPFIIMFCVPFAFVGVVLSLLVSGQSLSTVGMLGIILLIGIVV
                     NNGIVLIDYIEQLRKTNRNNDLIGLVSIGCAARLRPVLMTTATTILGMLPTALSLGEG
                     GETMQPLAIVIMGGLTVSTLITLVLIPTIYLIFDKWENKFSDKMPKIFGKITDKIGSI
                     KRKIIKKPKLKAKV"
     gene            12957..14267
                     /locus_tag="KRH23_002895"
     CDS             12957..14267
                     /locus_tag="KRH23_002895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TolC family protein"
                     /protein_id="HHS5226172.1"
                     /translation="MNKKMSKIVAIGCGVGIITANLIPVYADNNTSSINKVDNSILSD
                     SNKRTSEKEILTAREAVSAALKNSEKLKMKSEEIKMLKEKLEVQDEFDSFTGSDNSFP
                     YDQIGLLKNQSEQAKGFMEDQIANDITNKFNDLVSRENELDKIKNNLEIKTKEIKDMK
                     LKKDLGLVTSLETESAELELQTLQNTQKAKLQELKNNQDYFKLLTNIDLNNYQLDKEY
                     RFESFRVGGSVDSYMEGKVNEYLKYDQLILERTEESFNDKDENKADLPDRPNLTRPVA
                     PTKPEQGNLTDDEYKVLMDKYEKDYDRYKKEVEAYNLERQTYAAGLTTYANYLQQKFN
                     TENGLVTLEDSKKALKKGLIDSYAQLLALEDTIQITKKQLDLSEKQLKNTKLRYDLGL
                     ITLTDYKKQVVSNEDAKNSYDTLIVNYNSLKNGIEKPWILNTGK"
     gene            complement(14556..14801)
                     /locus_tag="KRH23_002896"
     CDS             complement(14556..14801)
                     /locus_tag="KRH23_002896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HHS5226173.1"
                     /translation="MTKCPKCGKEVSSRPGSICPRCGFKVADESLKIRCPEPSCRALV
                     SRKLDYCPKCGCKLRGYNISEFVNMVRCKIDETFDKK"
     gene            complement(15015..17642)
                     /gene="ppdK"
                     /locus_tag="KRH23_002897"
     CDS             complement(15015..17642)
                     /gene="ppdK"
                     /locus_tag="KRH23_002897"
                     /EC_number="2.7.9.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050242 - pyruvate, phosphate dikinase
                     activity [Evidence IEA];
                     GO_process: GO:0006090 - pyruvate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate, phosphate dikinase"
                     /protein_id="HHS5226174.1"
                     /translation="METKYVYSFGEGSKDMKSLLGGKGANLAEMTKIGLPVPPGFTIT
                     TEACNDYYVNNESIRAEIIKEIEEHLATLEKDLNKTLGCNKNPLLVSVRSGAVFSMPG
                     MMDTILNLGLNDNSVVGLAEATQNERFAYDSYRRFIQMFSDVAMEVPKYKFENVLDRV
                     KEAKGYTVDTELTTDDLKEIVKEFKAIYKKEIKNDFPQDPKEQLMLAIEAVFRSWNNP
                     RAIVYRKLNDIAHNLGTAVNIQSMVFGNMGETSGTGVAFTRNPATGENKLFGEFLMNA
                     QGEDVVAGIRTPQNISTLADVMPAVFDEFVKITHILEGHYKDMQDIEFTIENERLYIL
                     QTRNGKRTAAAAINVAVDLVEAGIIDEKEAIMRIEPNQLDQLLHPKFEDKALKEAKVI
                     AKGLPASPGAASGKVYFNADDVVKANEKGEKVVLVRLETSPEDIEGMVKAEGILTARG
                     GMTSHAAVVARGMGKCCVAGCGEIKVDEFNKEIRALDDVVIKEGEYISIDGSTGNVYL
                     GDVKKTEVSLTGNFEKLMNWVDKHKCMMVRTNADNPRDARAAIEFGAEGIGLCRTEHM
                     FFDEARLPAVREMILSNTVEQREKALEKILPMQREDFVELFKVMDGKPVNIRLLDPPL
                     HEFLPHDDETIEELSKSMGIKVSDIKKRIVDLDEFNPMLGHRGCRLAITYPEICVMQS
                     KAIIQGAIEAIKAGVKVSPEIMVPLVGEVNELKIIRKMIVETVDAIIKEEGIEVPYTV
                     GTMIEIPRACLTADEIAQEADFFSFGTNDLTQMAFGYSRDDAGKFLGQYVDEEILEKD
                     PFQVLDQNGVGKLVKMGAKLGREVKPELKLGICGEHGGEPSSVEFCYSVGLNYVSCSP
                     FRVPIARLAAAQASIKNPR"
     gene            complement(17703..18545)
                     /locus_tag="KRH23_002898"
     CDS             complement(17703..18545)
                     /locus_tag="KRH23_002898"
                     /EC_number="2.7.11.33"
                     /EC_number="2.7.4.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004674 - protein serine/threonine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016776 - phosphotransferase activity,
                     phosphate group as acceptor [Evidence IEA];
                     GO_process: GO:0006468 - protein phosphorylation [Evidence
                     IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate, water dikinase regulatory protein"
                     /protein_id="HHS5226175.1"
                     /translation="MLVKNLIIYAVSDSVGETAQQVAKACMSQFYVNETYEIKRFPYM
                     INKGVLLETLENAKAENALIVYTLVDEELCSIVERYCEREGLSCIDLMTDILREISKR
                     TGRKPKREAGIIRKLDESYFKRVEAIEFAVKYDDGKDPRGVLQADIILVGISRTSKTP
                     LSMYLANKNIKVANVPLVPEIPIPKEVFEIDTKKIIGLTNSPEKLNEIRTQRLKALGL
                     SSKANYANLERILQELDYSEEIMKRIGCPVINVSNKAIEETAGIILDIMKENGLKIYK
                     EIEI"
     gene            complement(18552..19190)
                     /locus_tag="KRH23_002899"
     CDS             complement(18552..19190)
                     /locus_tag="KRH23_002899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HHS5226176.1"
                     /translation="MIIIQLNERQLKIIDIVKENEPITSESIASSLNVTRATLRSDLA
                     ILTMTGILDARPKVGYFYSGVSEINLIGKSVKEKTVEDIMSMPVLAKKDESIYDVIVT
                     MFLSDVGSIVIIDENEELCGVVSRKDLLKATIGGSDINKMPIGMIMTRTPNVVTLTKG
                     ASVLLASRKIIEHEVDSIPIVEYKGEDKNHMRVVGRISKTNITKLFLEIVDN"
     gene            complement(19626..20918)
                     /locus_tag="KRH23_002900"
     CDS             complement(19626..20918)
                     /locus_tag="KRH23_002900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HHS5226177.1"
                     /translation="MLDLNRKLAKLEEEGKKIKVALIGAGHMGNGMVSQMANMKGIEA
                     SIVVDIDLELAHKAFTDAGIDEEIIDNVTNEKDAEIKLQEGKVLTCNDFLVACKTKSI
                     DVVIDATGGIAIGAEIALNSILNKKHIVMLNAETDCVVGPILKKLADDAGVIFTGSAG
                     DEPGAVMELFDFADAMGFEVRVIGKGKNNKLDLDCNPDTVREEAERKGASPHMIASFK
                     EGTKTMVEMALMCNATGFVPDVRGGHGIEATVNEVPKKYALKSEGGVLDNYGVVDFVN
                     GIAPGVFVVVAHKLKAVNDELKYLSMGDGPNYILYRPYHLCSLETPLSAAMAVLDHKA
                     TIVPKAGLVAEVMTIAKKDLKKGEFMDGYGAYTCYGTIEKYDVAKAMNAVPIGLISKK
                     TKVVKDIKKGEVITYDMVEIEKDTTLYHLRQLQEKIFG"
     gene            complement(20955..21311)
                     /locus_tag="KRH23_002901"
     CDS             complement(20955..21311)
                     /locus_tag="KRH23_002901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HHS5226178.1"
                     /translation="MKYEVKISGIGSLVKELMDESNCLIIYDETINDDDLKDISVIHS
                     IATLKSDVEIGDTLTIGNRDYCIVSVGDIAQKTLREIGHCTIKFDGKCEVNLPGEIHV
                     EIGNPDITIGDLITIS"
     gene            complement(21346..21705)
                     /locus_tag="KRH23_002902"
     CDS             complement(21346..21705)
                     /locus_tag="KRH23_002902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator GutM"
                     /protein_id="HHS5226179.1"
                     /translation="MKLLVILFVAYILNTIFIMKQNKLYFKTLNRAKKKGDIVSTGKK
                     KSYFSKGSIAVISSDSDGFIKFGEILKGRTVMAKFKEIEEIEGLDIYSAEQKFKDEES
                     IVQAIKFIKEKINVSFN"
     gene            complement(21774..23747)
                     /locus_tag="KRH23_002903"
     CDS             complement(21774..23747)
                     /locus_tag="KRH23_002903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HHS5226180.1"
                     /translation="MSVTEKIPSIDRKIFKILIMCSKKEFVSINSIANELNVTTRSVR
                     TYIKQLNKDLGNDIAVIKYIKGQGYKLEIKDEQILNKIIDMNRKNVFSLNSKEDRVEF
                     ILNYLIELDGFITLDSLADEMCVGRTTLVNDFQYVEKVLASYNLNLIKKQNTGMKLNG
                     NELDIRLFILNQLYKNSRKDFSNSKYFKGIKKEEIINLEEKLLTLFKKNNFYVTDEML
                     REVINYIVVLVYRVKEEKKVKDYDVKFDLLKSYDEYFIAREIKHIISGMFECTLNDEE
                     IIYLTIPLVSGNAPASECALNSSRISKNIDELMENIFNQIYVDMGIFINEDELRVGLG
                     YHLSFTLNRLLFNIKLKNVLLEEIKQNYILPFKLAQIAGKVIEKKYNLEVSEDEIGYI
                     AIHFSGYLERNSSRFYSIKKIAIICSTGLGTAKLLKIRVEKLIGNNPKIDTLSSFNLR
                     NINLDEYDIVFTTIDLDTSNINTIVLKINTIFDENKLREQLKTVLCLREGNIDTTNST
                     NLLINNLLDEDKFMILNEKTILASLEKMMDHLMDLGCIDDKFRKNIVNREEKSPTVFD
                     KGLLFPHSVNEKSDKFLMAVGILEEPIEYANRSIKIILMTMFPCENKIDSDLLVKIYE
                     EVLKIGQDVKLTNKISKCRTFLEFKKVLLKNLI"
     gene            complement(23969..24982)
                     /gene="srlE"
                     /locus_tag="KRH23_002904"
     CDS             complement(23969..24982)
                     /gene="srlE"
                     /locus_tag="KRH23_002904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015795 - sorbitol transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HHS5226181.1"
                     /translation="MEENKILKIEKGTSGWGGPLYIKKEGNRNKILSMTAGGIHEVTL
                     KIKELLGCEIVDGFKTGVSDEEVAVVIIDCGGTARCGVYPKKKIPTINVNPVGKTGPL
                     AKFITEEYYVSDVNPNCISVVDGEDMPQKSQENKSENKSSIRKPDNYDEVKSKAQGEY
                     AKKNIILSIGQGAGQVVSKFYDAGRDTIQMVMNNVIPFMAFVSMLMGIILASGLGDWI
                     ARVISPLAGNIGGLLIISVICTLPFLSPILGPGAVIAQVVGTLVGTQIGLGAIPAYLA
                     LPALFAINGQAGCDFVPVGLSLGEAEPETVEYGVPALFYSRLITGPIAVIIAYGVAVF
                     ALR"
     gene            complement(24995..25540)
                     /gene="srlA"
                     /locus_tag="KRH23_002905"
     CDS             complement(24995..25540)
                     /gene="srlA"
                     /locus_tag="KRH23_002905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015795 - sorbitol transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HHS5226182.1"
                     /translation="MENVITGLSKGAEWFIGLFQKGGEQFIGLVSGTLPTLIVLMVAI
                     NSLIKIIGEERVNNWASKLGKNSFTRYILLPLVSVFFLGNPMCYTFGRFLKEEHKAGF
                     YDAAVSFVHPITGLFPHANAGELFVWLGISAGLTTLGKETTTLALWYFIVGLIVIFIR
                     GIVTEKMYAFLTRKNRATNKA"
BASE COUNT         8776 a         4263 c         3267 g         9340 t
ORIGIN      
        1 acaacattta agttattaca tttatttata tatatttttt cattatctaa gtcttcatca
       61 aacattttta ttatattttt tatctcatac ttgtactcat cttcattcat tctataaagc
      121 attaaatctt ctagtacatc tttcatatcg aagtacacat cttctaataa ataaaaatag
      181 ccttcctcta tatctttcaa tttatctata gtatccattt ttttacttat gtctttcata
      241 atttctaaat tttgtatatt tacatctatg attgttaata agtacattct cacagttttt
      301 attatttcaa cagaaaaatc tacaatatta taatttcctt cttttttata taatgactcc
      361 ttaaatttgt taaaacaatt atctaaatta gaatttatat cgttaaatgg tggtcttatt
      421 atgtcacgta ttattaaaag attttgtatg tctacattat ttgtgattgc ctcatccaaa
      481 ataaataaat tatatgcatc atttaatggg tcatgggcat ctccactaaa ctctaagtta
      541 acaaattcta gtaaattttt caatgatata tagttcatac atctcatacc acaatttata
      601 tatttttctt ttatatctac aaataaatct ctaatgttat ttacaaacct tggatggtta
      661 ttttttttag cacttctcat atctgtgtta ttgaaacatg tcaaatccaa attaccaaaa
      721 gtatatattc ctttaatatc agaaaatatg ccaagccatt ttttaaactt tctcatgacc
      781 tcttcataac ttggtgcact cttcaattct tcagaagata tatgtgttaa ttcttgtata
      841 tgaggataca actcctcatt acttactggt cttattaaag atttaaattt atcaatattt
      901 tttgtttttt catcatacat aactgctccg attgcaatta tatcagaatt aaatactgct
      961 ctttttgatt tagaatttgg catattcatt tcaaaatcta tatatactct tttcaatata
     1021 aacacccttt ccaattgttt atagtgattc tttttaacta tttttattca aaattttcta
     1081 agaaagaatg tttctcccca tctttttgcc aaccaagtac tgaatcaaga tttacatttt
     1141 ctgctgcctt aaatatagat ttttctacat ttttaaaatt tgattctaag ctctttatta
     1201 agtcttttat ctcatatctt ttattacctg tttttttagc agcaaccata catgcacaat
     1261 ttaatggcca tataccacta ttttgaataa atcttataat atgttcttct cttatataat
     1321 aaagtggtct tataattttt ataccttcaa aattagtaga attaagttta ggaagcattg
     1381 ttttaaaatt tccagcacac aataagttaa gcattgttgt ctctattaca tcatcataat
     1441 gatgacctaa tgcaagtttg ttgcacccta attcttctgc ctttgaatat aatgctcctc
     1501 tcctcattct tgcacacata tagcatggat aatcttttgc tatttcatct gctatctcaa
     1561 atatccttga atcaaataaa tgtattggta tatttagata ctcacaatta tctataagta
     1621 attgtcttat atttgcatga tatccagggt ccatagcaat aaattcaaca tcaaaattaa
     1681 cttgtccatg tttttttaac tcttgaaaca ttttagccat aagaatactg tcttttccac
     1741 cagaaatcgc tacagctatc ttatcacctt cttcaaccaa tttataatct cttattgcct
     1801 tcataaactt agaccataaa tttttcctat atttttttat tatacttttt tctatatctc
     1861 ttactggaag tctttcctca aaaggaacta taatttcaca gccttttcct gatagttcac
     1921 tcatctaatc acctcgtata tttatgttaa taatatttta caaaaaagtc taccttcatc
     1981 cacaaaatac tataattttt actttaattt tactaaataa tttatagttt acaataacac
     2041 ataaacttat aataacataa ataacctctt tcttttatta tcttttttat ttttctcatt
     2101 taatatttta ttattagtaa cgatttttaa atgattgaat attatacact agatagagtt
     2161 acctatctat ttacaacaag gaggttttca tcttggaaaa taagactaga gatatcaaaa
     2221 aaaattgtgg tccatctttg gctagaccat acattaataa tcaaattttc acagaaatgt
     2281 actgcctttc tgatgcatta aaatttggaa ctatatttcc agaactaaac ttactagagt
     2341 ctgaaatgta caacaaagaa ttatatgcta agccaaaaaa atatagagga ggtagaagat
     2401 aatgaaagac tcatctagag ctgaacttat gagaaaagtt caggaaacat cttttgcatg
     2461 tgttgatatg aacttatatt tagacaatca ccctgatgat aaaaatgcta tcaacactta
     2521 taattcatta tgtaatcaat ttgcgcaagc tagatatgct tacgaaaata aatacggtcc
     2581 tttaactaac tttgggtatg ctccaagtag atgcccttgg caatgggctg accaaccttg
     2641 gccttgggac agagaattta attattagac atcaagtatt ggaggattga aaattcatgt
     2701 ggatatatca gaaaactata caacacccag ttaatataaa aacttgtgac cctagaatgg
     2761 ctaaatttct tataactcaa tttggtgggc caaatggaga acttgctgca tctttaagat
     2821 atttaagcca aagatataca atgcctactg gtaatatgcg tgcactttta acagatattg
     2881 gtacagaaga actagctcac gttgagctta tatgtactat ggtttatcag ttaacttctg
     2941 atgcaagccc agaagagtta aaagctgcag gtcttggttc aaactatgct caaaatggat
     3001 atggaattta tccaacagat tcaaatggtg ttccatttga tgtaagacct atagcagtta
     3061 tgtcaaatcc cgtaaccgat ttacatgagg atatggcagc tgaacaaaaa gcacttgcaa
     3121 cttattatca acttataaac ctaacagatg acgttgatgt tatagatgta ttaaaattct
     3181 tgggtcaaag agaaataatt cactatcaaa gatttggtga agctttaatg gatgcttacg
     3241 agttagaaga atctcaaaaa atgttctaaa atttttattt gtataactat tattatttga
     3301 taatttataa tttactgttg tgttaaaatt tataaaaaat ataaatataa tttattttct
     3361 ataaacagag aaaataaata aaaagcaggt atcaataaaa tagtaacatg tattatacta
     3421 tacattacta tcaatattgt acctgctttc atattataag caataaagaa aaatctattt
     3481 attaggtttt ataataaaaa caattataaa actcttcttg catttacata tctacttgaa
     3541 tagtagctac tatttatatt agatattgtt actttttttg atgaacctga agatgcatgt
     3601 atcatatctc catttcctat gtatattcca acatgactta cagaaccatt atttgaacct
     3661 tgtgtatcaa agaatactaa atctccactt ctaaggtctc ctctatttac atatgttcca
     3721 tacttacttt ggtctctaga tactcttggt atactaactc ctacagattt tttcataacg
     3781 tactgtgtga atccagaaca gtcaaaacta tttggacctt ctgctcccca tacatatggt
     3841 tttccaagta gtgtctttgc aaaacttatt acactatcag ctccttgact tggagaatta
     3901 gtcgaataag atggaattga agtatcaaca gaaccttttt cagcaaggta ttgacttgac
     3961 acatatccag tttgattgcc ataacttact tttgtccatc ctccactttc agaaatactt
     4021 ccaacctcag taccataact taatgtagct attttagaat gacttgtacc tggtcctgtt
     4081 ctaacgttca atgactttgc tgttacaacc tttgtaccct ttacaaggtc atttgaactg
     4141 ttttcagcat tttcatttgt agagtcattt acactagttc ctaaatattt acttgaaaca
     4201 taacctactc taccattaga acttattttt gaccatccat ttgactcaga tatgtatccg
     4261 acttcagtcc catatcctag tgttgatatt ttagaactac ttgtacttgg tcctgttcta
     4321 aaatttaatc cttttgctgt tacaactttt gtcgacttaa ctgaagtatc actactttca
     4381 ttgctacttc caaggctatt tattgctaca taatttccat gcacataacc tgtgtttcca
     4441 ttatatttaa cttttaccca agaaccttct tttcctacgt actcaacttt atcacctttg
     4501 taaagtttcc ccattgattc atggtttgta cctggtcctt ttctaaaatt taccgcattc
     4561 cctgttattg ttctgctttc tatactcaca ctctctactt cagactcatt agcatatgct
     4621 aaattcccca tagtaggcat tattatcgca gttgccatta tactggctgc tattctcttt
     4681 tgattaaaat tcataacttt ccactcatct cctcttttct actatcttta tttcacttca
     4741 aaatataaaa gaaataattg acactattaa aatatcaatt atttctttta tattaatatt
     4801 attacaaatt tgtaactatt tgtctatagt aatatttgct taccataaat taccatgtat
     4861 aaattttaat ctttaatagc ctgtaattta gtaatatagc catcttttag cttttttaaa
     4921 aatggctata ttttttaact tttttgtaac tttttaaaat ccagttgagc caaacccacc
     4981 ttttcctctt tcggagtcac ttaattcttt tacttcttct atgttaatat catagatagg
     5041 ttttactatc atttgagcaa ttttcatatg cttttcaacc ttaaaatcat ttttaccatg
     5101 atttattaat ataattttaa gctctcctct gtatccttcg tcaatagttc ctggtgtatt
     5161 taatacagta acagaatgct ttaaggcaag cccacttcta ggtcttacct gcgcttctgt
     5221 catagtagga agctctatac atatcccagt tttgataagt ttagtctctc caggaggtat
     5281 tacaacctct tctatagaat acaaatccat accagcatca cctttgtgag caaaattagg
     5341 tattatagca tcatcattta atttttttac ttttaaattg tacatcttat atctcctttc
     5401 aactttctat aaatattata acttaaattt cgacctcttg aagtttttta tttttttgtg
     5461 gtaatataat tattagtgtt ttaaaggagg attttttatg aaacttgtac ttgctgagaa
     5521 accatctgtg gcaaaaacta tagcatcatt tttaggtgca aagaccagac aagatggtta
     5581 ctttgaagga aatgattata taattactta tgcagttgga cacttagtat cattatatga
     5641 tatgaaggat tatgataaag ataaatactc tggctcttgg aaaatgaaca atttcccatt
     5701 tgttcctgag gataagttta aatttaagat tgatagttct aaaactaaac aattcaacac
     5761 tgtaaaaaag cttttgaata gaaaagatgt agaatatgta ataaatgcca ctgataatga
     5821 ccgagaagga gaacttatag catttttaat atttttactg gcaaaaaata aaaaaccagt
     5881 aaaaagaatc ttggtaaatg aatggacacc agaagatatt acaagaggta taaaaaacct
     5941 aaaagatgaa gatgaaatga gaaatcttca agctgctgga tatactaggc ttattactga
     6001 ctggttgatt ggaataaatt tcacttctgt tgctacattg aaatacggaa atgggaaact
     6061 attaaacata ggtagggtaa ttcttccaac agttaaatta gtctatgata gagatatgga
     6121 aatactaaac tttgttccta aaacttatta tgaaatagaa gggcatttta aagctgaagc
     6181 tggtgaatat aaaggtaaat atgttaaggg taaagaaagt aaatttgata cacttgaaga
     6241 tgcaaataaa attatagctt caattacatc tgaaactggt aaaatactag ataaaaaagt
     6301 tactatgtca aaggaatatg caccaaaact ttttagtttg acatcacttc aaggatatat
     6361 aacttctaag tattccaatt ttacatctga taaggtttta aatgtctgtc aatctctcta
     6421 tgagggtaat ggtaagggtg gatacataac ttaccctaga actgattcca ttttcttaga
     6481 agaaagtttg gcttcaaaag cttctcaaac tttagataaa ttaaaggttg gtcttgaata
     6541 tgaaaataaa attaaatttt ctaaaactaa aagagttttt gattcttcta aagtagactc
     6601 ccatagtgct ataattccaa cttatataat tccaaaaagt ttatctaagg atgaacaatt
     6661 agtttatgat gccataaaag atagatttgt agcaaatttt atgcctcctg ctgaatatga
     6721 gaatacagaa attaagactg aagtagataa ttgtactttc ttaacaaaag gtaaggtgct
     6781 taaatcaaaa ggataccttg aggtatataa taaggaagaa aaaaacgatt tacttccact
     6841 tgtaaataaa gatgatgttg tagatgtgtt agaaataaaa ccattaacta agcaaactac
     6901 tccacctaaa ccatatactg aggacaccct tttaaaggct atgaaaaatt gtggtaaaaa
     6961 tgtgcctgaa gaagatacaa cagtgctatc tggatattcg attggaacat cagccacacg
     7021 tgctgatgtg ttaaagaaga taagtcaagt aggctatgta aagaaaaaag ggaaatctta
     7081 ttctataaca gaccttggga aaaatttagt tgaaattttt cctgttaaag acttatttga
     7141 tgtagattat actggaaaac ttgaaaaaag tttaagcgat attcaaaaag gaaagtatac
     7201 aagaaaagaa tatcttacta atatcattag ttttatatat caaaatgtca atattataaa
     7261 acaagatgct tcaaaaaata taaacacaga agcatatact ttcgattcaa aaactaaaaa
     7321 atttactaaa acaaaagaaa aaaaacagaa aaaagatgta actaatactg aaaaagaagt
     7381 tgctatatca aaggattcta ataacaaaaa agaagttaaa aatggtgatg aaaatcaatc
     7441 tcttggcaaa tgccccattt gtcaaggtga tgtactagaa tttgacaaag gctttgcttg
     7501 taaaaatcat aaagaatgta aatttgttat ttggaaaaat gataagtatt taagtcttta
     7561 taaaaagaaa gttaacaaaa caatggtcaa aaatatttta aaaaaaggtg aaactaaagt
     7621 aaaatcttta actgctaaaa acggtaataa atttgatgct acattaaaat atgataaaaa
     7681 tccagatacc ggctatttca attggaaaat agagtttgac aactaaatat tcataagaaa
     7741 agaaatagca gtagtataat aatctatatt atattactgc tatttctttt cttatgaagt
     7801 tttaactttt ttaatagtga cttttacaat cacactctaa cctaatttct ttactatttc
     7861 tgataacttt aatgtatgtt catctaataa agttagttcc tcttcagaaa gattagataa
     7921 tttttttact agagattctt tgagaatagc ttttactgca tcaaataatt taaatgcttt
     7981 atctgttaat tcaaccctaa gaatccttct atcttttggg tcaggaaatt tattgactaa
     8041 accatgttcc actaatctgt caataatcgg agtcatattt gattttaaaa ttcctaaatt
     8101 agaagctatt tgagaaattg atgatgaatt tgatgtcata agataaagaa ttaccttagc
     8161 atgtgatgga gccattggac attcttcaaa ataagctttc attatatcag agttattttg
     8221 aaactttttt aacaaatcgc tttctttaaa tatattattt tcaagcacaa ataaaaaatc
     8281 taaaaaagag tccgctattt taagtatatt gttgttatcc atatttgtaa catcccttca
     8341 atagataata taataaaaca ttgttgttta atatagtata aattataaac tattaataaa
     8401 tttaaaacaa gaaaaagtta ttgactcata ataattataa atttataatc aaattagaga
     8461 attataaatt gccaataaag ggaagttttt taattagtct aaaactaaac ttaaattata
     8521 agacacttta aattctacaa caagctagtg tgcaatatat aataggagga gatatgaaaa
     8581 gatatttaat agttttctta atgtgtagtt cactgttttt agttggatgt ggaaaaacag
     8641 aagaatctga acctgagaaa ccaatagcag tttctgttca aaaagcagtg ggtggagaaa
     8701 ttgaaaacac aaattctttc tcaggaacta caaaggttaa agatgaaaca gctgttactg
     8761 cacagactgt tggcacagtt caagaagtgt atgtaaaact tgggcaaaat gtaagaaaag
     8821 gagatgaatt attgagtata agcagtccag agctagaaaa tagtgtaaaa caaagtaaag
     8881 cctcactaga tttagcaaaa gcaagttatt caagtgccac tggtggttca ttagaggcac
     8941 aagtaaatca ggcaaaaaca gctcttgaca atgcaaagat tcaatatgag gagtctcaaa
     9001 gaaattatga caataataag attctttatg aacaggaagt cattagttta gaccaattta
     9061 aaaaaataga gttttcttta gagcaaacaa agcaacagtt agattctgct caaagagcat
     9121 acgatacagc aacttcaaaa agtatacctc aagctaaagc acttgctaaa aaacagcttg
     9181 accaagctca agtatcatat aatttagcaa tgagtaattt agacaaatta acattaacat
     9241 ctccagtaga tggtacaata acagctaaaa actttgattc aaaggaaatg ataacacaat
     9301 cacaaccagc ttttattatt tctaatccta atatactaga agttgattta aatgtagcag
     9361 aatcagatat aggtaaattt aagaaagatg gaaatgtaga tgttataatt gaagaccaaa
     9421 ggattttagg aaaaatagat tatgtacctt cagtagttga ccctcagaca tctttatatc
     9481 ctgttaaagt acttgtaaat aatacaaaca acaaatttaa ggcaggtatg tctgctcaag
     9541 taaacttaag tgttgaaaaa gaaaatggtg ctgttacagt acctaaaaaa gcaatatttg
     9601 aagaaaatgg taaaaaatat gtatacatag caacaaaaga caatatagca aagaaacact
     9661 tggttcaaac tggaattgta acagaggata aaatagaaat taaaagtggt gtaagtgata
     9721 aagatacagt gattatcgga gggataagtc ttatttctga cggaactaag atatttcctg
     9781 tagaaaagga gaagtagact atgaatttaa cacagacttc cgttaaacgt cctctcacaa
     9841 tcataatggt ctttttagta ttaatagttt ttggtggtat tggatataaa aaaatgtcaa
     9901 taaatctaat gcctgatata gaaataccag ttgtaatggt catgactact tggacaggtg
     9961 ctggtcctca agacgttgat gaacaagtta gtcaaaaagt tgatgaaagt ttatctgccg
    10021 tttcaaatgt aaaatctact atatcaagtt cacaagaaag tgtttctatg gtagtagctc
    10081 aatttgaatt tggaactaat ttagatgaaa taatgaatga tgttaggtct aaagtagatg
    10141 cattacagac catcctccca gatgatgcag ctaaaccaac agttttaaag ctggatatga
    10201 atgcacaggc tataggtcaa cttgtcatat ctggaggaaa tgaaaatagt tcacaagcct
    10261 taagaaaata cgctgaagat gtaattcaac ctaaaataga atccatagat ggtgttactt
    10321 cagcagacct taaaggtgga aaaaaagcac aggttaatgt aatagctgac ccagctgttc
    10381 tttcaaatta tggagttagt ttatccacta taaaaggtgt cttatcctct agtaataaaa
    10441 cattccctta tggttcaatt actcaaggtg aggataaaat agttttaaga gcaattgata
    10501 aattagaatc cctagatgat ataaaacaga ttcaaattcc tgtaaaagga ggaaatacag
    10561 ttagattaga taatctttgt agtgtagatt atggatatgc agacaaagat agtatttata
    10621 gatacaatgg aaaagacagt ttggtaatag atatttctaa acaacaagat gccaacactg
    10681 taaaagttat gcagagtgca tacaaatacg tagatgaatt gaataaggaa aatcctcaat
    10741 ttaaaattaa aattgctaat gatacaagtt catacataag tgaatcaata aacagtgtaa
    10801 tgagcaactt gcttataagt gctgttatcg catttattgt aatatttgct ttcctaaaaa
    10861 gtgtaagagc ttcactagtt gttgcagttg caataccaat ttctataata ggtgctatag
    10921 caattctcta ctttactggt gaaagtttaa atcttattac tgcaagttca ttggtaattt
    10981 cagttggtat ggttgttgat aatgctacag ttgtaattga aaatatattt aaatatagga
    11041 aaagtggcag attgagtctt gatgattgtg ctattgaggg aacaagaact gtaacaaatg
    11101 caatacttgc atcaacattg accacgatag caatattctt acctatcatg tttacagaag
    11161 gtatagctaa aataactttt ggggcattag gtaaaacact aatagcttca ctagcattct
    11221 cctttatagg tgcaattaca ctcgttccta gtgtatttgc aaaattaagc agaggaaaaa
    11281 atagtcaaaa gatgcaagaa aaagatagtc ctatatttga taaggtaagt gaagcatata
    11341 aaaaattatt aagtgtatgt ttgagacatc aacgcttagt tgtaatatca agtttactta
    11401 tttttgtagc ttccttattt ggaatgggat ttataggtat ggactttatg cctgcagcag
    11461 acaagggtga attatctatt tctatagaac ttccaaaagg tcttagccta gaatccaatg
    11521 attactatgt atctatgact gagaaaaaag tctcagatat tccagaaatt aaaactttaa
    11581 taacaacttt gacatcagat tcaaataata gtaaagcaag tatagcaatt gaattagaat
    11641 ctcaaaaaaa tagaaaaaga actactgatg aaatagaaaa agagataatt gatagagtgg
    11701 ctactgtacc agattgtaaa ataaatgtaa gtcaaaacag tagtgttatg ggtggagctg
    11761 gaggagcaga cttcacatta gaaatgaaag gtcctgattt agatgtatta aaaatactgg
    11821 gaaaagaagc tgaaaaagaa tttagctcta taaaaggatt tagaaatgtt gaaacttctc
    11881 ttacagatac aacacaagaa gctcaattta ctatagataa acataaggct caagaatatg
    11941 gtgtaaatac tgctgaaatt gcaggcatgt tacgtacagc aataaatggt gactccgtaa
    12001 ccactgctac tattgatgat tacaaagtgg atgtaaacct aaaatttaaa gcagatacta
    12061 ttgatagctt agaagatata aagcaactaa aagtaaactc tgcaactgga aaagaagttc
    12121 ctcttggtgc tttttcagat ataaaaatgg cagatggtct acaatctata tctaggactg
    12181 atggagattt ttctgtaaat ataactgcta cacttgacaa tttagatgct ggtactgcta
    12241 caaaactagc actagaaaaa acgaataaaa tggtaattcc taaagattac tctataggtg
    12301 ttggtggtga aacagaaatg atgaatgaat ctatggcaag tcttggattt tcaatggtca
    12361 tagctatagc attagtttat atggtaatgg tagctcagtt tgaatcattt agtaaaccat
    12421 ttataatcat gttctgtgtt ccatttgcat tcgttggagt tgtgctttcg cttctagtta
    12481 gtggtcaaag tttaagcact gtcggtatgc taggtataat cttacttatc ggtattgttg
    12541 ttaataatgg tatagttctt attgactaca tagagcaact tagaaaaaca aatcgtaaca
    12601 atgatttaat tggtttggtt tcaattggtt gtgcagcaag attaagacca gtcttaatga
    12661 ctacagcaac aacaatttta ggtatgttgc caacagcact atctcttggt gaaggtggag
    12721 aaactatgca accactagcc atagttataa tgggtggtct aactgtatct acacttataa
    12781 ctttggtgct tatacctact atatacttaa tatttgataa atgggaaaat aagttttcag
    12841 acaaaatgcc taaaatattt ggtaagataa cagataaaat aggaagtata aaacgtaaaa
    12901 taataaagaa accaaaattg aaagctaaag tttaaataga atggagggtg attgtattga
    12961 ataaaaaaat gagcaaaata gttgcaattg gctgtggtgt tggtataata actgccaatt
    13021 taatcccagt ttacgcagat aataatactt cttctataaa caaagttgat aattctattt
    13081 taagtgactc aaataaaaga acatctgaaa aggaaatttt gactgctaga gaagctgtta
    13141 gtgctgcact taaaaatagt gaaaaattaa aaatgaaatc agaagaaata aaaatgttaa
    13201 aagaaaagtt agaagtacaa gatgagtttg atagttttac tggaagtgac aactcgtttc
    13261 catacgacca aattggactt cttaaaaatc aaagtgaaca ggctaaaggc tttatggagg
    13321 accaaatagc aaatgatatt actaataaat ttaacgattt agtttcaaga gaaaatgagc
    13381 tagataaaat aaaaaacaat cttgaaataa aaactaaaga aattaaagat atgaaattaa
    13441 aaaaagattt agggttagta acatctttag aaactgaatc agctgaactt gaacttcaaa
    13501 cactacaaaa tactcaaaaa gctaaacttc aagaactaaa aaacaatcaa gactatttta
    13561 agttattgac taatatagat ttaaataatt atcaattgga taaagaatat agatttgaat
    13621 cttttagagt aggtggctca gttgattcat atatggaagg taaggttaat gaatatttaa
    13681 aatacgacca attgatttta gaacgtacag aagaaagctt taatgataaa gatgagaaca
    13741 aagcagattt accagataga cctaacctta caagaccagt tgctcctaca aaaccagagc
    13801 aaggtaacct aactgatgat gaatacaagg ttcttatgga taagtatgaa aaagattatg
    13861 atagatataa aaaagaagtt gaagcataca atcttgaaag acagacttat gctgctggcc
    13921 ttactactta tgcaaattat cttcaacaaa aatttaatac tgaaaatggt ctagtaacat
    13981 tagaagacag taaaaaagct cttaaaaaag ggttaattga tagctatgct caattacttg
    14041 ctttagaaga tacaattcag attactaaaa aacaacttga tttatcagaa aaacaattaa
    14101 aaaatactaa attaagatat gatttaggat taattactct aactgattat aaaaaacaag
    14161 tggtaagtaa tgaagatgct aaaaatagct atgacactct tattgtgaat tataactcac
    14221 taaaaaatgg tatagaaaaa ccttggatac ttaatactgg aaaataattc tggtaaatag
    14281 aaagattact ttaacatacg tttgattaaa aaatagttat gcacactcgt ggctttagtc
    14341 atggaagatt cagaaggcaa ataatagaaa tagattagta aaaatatatt tacttataaa
    14401 actgtatact tttatagagg ctatctcaaa atagagataa gcctcttttt tattgtttaa
    14461 attataaaaa tatatttgat tccatacaaa aagagtgcct tatgaactaa aaagtttatt
    14521 ttgagacacc ctcaaaagct taactctaaa tttaattatt ttttatcaaa tgtctcatct
    14581 attttacatc tcaccatgtt aacaaattca gaaatattat atcctctaag tttgcatcca
    14641 catttaggac aataatccag tttcctagat accaaagccc tacaactagg ttctggacat
    14701 cttattttta gactctcatc tgctacttta aatccacatc gtgggcatat actacctgga
    14761 cgtgatgata cttcctttcc acatttagga cactttgtca actttatccc ctccagtaaa
    14821 ctcaatttaa ttgatagttg aaatttctct ctacaataat atatgcaata taattaaata
    14881 tgtttcactt acaactatat aagttaaatt tttataataa aaatccccta tattcaattt
    14941 ataaatactt aatttgatac attgaacaat aggggatttt atttttattt agttacatat
    15001 tttgcagtct attattatct aggatttttt atagatgctt gagctgctgc aagtctagca
    15061 attggcactc taaatggtga acaagataca tagttaagtc ctacactata acagaactct
    15121 actgaagatg gttctcctcc atgctctcca catattccta gttttaattc tggtttaact
    15181 tctctaccta atttagctcc catcttaact aacttaccaa caccattttg gtctagtact
    15241 tggaatgggt ctttttctaa tatttcttca tctacatatt gacctaagaa tttaccagca
    15301 tcatctcttg aatatccaaa tgccatttga gttaagtcat tagtaccaaa actgaagaag
    15361 tctgcttctt gtgctatttc atcagcagtt aaacaagctc taggtatttc tatcatagta
    15421 cctacagtat aaggaacttc tataccttct tcttttatta tagcgtcaac agtttctact
    15481 atcatttttc ttattatttt taactcattt acttctccaa ctaatggaac cattatctct
    15541 ggagaaactt taacacctgc tttgattgct tctatagcac cttgtattat agctttagat
    15601 tgcattacac atatttcagg ataagttatt gcaagtctac aacctctgtg tccaagcatt
    15661 gggttaaact catctaaatc aactattctc ttcttaatat cacttacttt tattcccata
    15721 gattttgaaa gttcttctat agtctcatca tcatgaggca aaaattcatg tagtggtgga
    15781 tctagtaatc ttatattaac tggttttcca tccataactt taaataactc tacaaaatct
    15841 tctctttgca ttggtaatat tttttcaaga gctttttctc tttgttctac tgtattagat
    15901 aatatcattt ctctaactgc tggcaatcta gcttcatcaa agaacatatg ctcagttcta
    15961 catagaccta taccttctgc accaaactct atagctgcac gagcatctct aggattatct
    16021 gcattagttc taaccatcat acatttgtgt ttgtctaccc agttcattaa tttttcaaag
    16081 tttccagtta aagatacttc tgttttctta acatctccta ggtacacatt tcctgtagaa
    16141 ccatctatag aaatgtattc accttctttt ataactacat catcaagtgc tcttatttct
    16201 ttattaaact catcaacttt tatttctcca catccagcaa cacaacattt acccatacct
    16261 ctagcaacaa ctgctgcatg tgatgtcatt ccacctctag ctgtaaggat tccttctgct
    16321 ttaaccattc cttctatatc ttctggagat gtctctagtc taactaaaac tactttttct
    16381 cctttttcat ttgcttttac tacatcatca gcattgaaat aaactttacc acttgctgca
    16441 cctggtgatg ctggtaaacc ttttgctata accttggctt cttttaatgc cttatcttca
    16501 aattttggat gtaataattg gtctaattga ttaggctcaa ttctcatgat agcttctttt
    16561 tcatcaatta ttccagcttc aactaaatca accgctacat ttattgctgc tgctgctgtt
    16621 ctcttaccat ttctagtttg tagtatatat aatctttcat tttctatagt aaactctata
    16681 tcttgcatat ctttataatg accttcaagt atatgagtaa tttttacaaa ttcatcgaat
    16741 acagctggca ttacatctgc aagagttgat atattttgag gagttcttat acctgcaaca
    16801 acgtcttcac cttgtgcatt cattaaaaat tcaccaaata atttattttc tcctgtagct
    16861 ggatttctag taaatgcaac acctgtacca ctagtttctc ccatattacc aaataccatt
    16921 gattgaatat ttactgctgt tcctaagtta tgagctatat cattcaattt acggtatacg
    16981 attgcacgag gattattcca tgatctaaat acagcctcta ttgcaagcat taattgctct
    17041 tttgggtctt gtgggaaatc attttttatt tcttttttat aaattgcttt aaattctttt
    17101 actatttctt ttaaatcatc agttgtaagt tctgtatcaa ctgtgtatcc ctttgcttct
    17161 tttactctgt ctaatacgtt ttcaaattta tattttggaa cttccatagc aacatcagaa
    17221 aacatttgta tgaatcttct gtaactatca tatgcaaatc tttcattttg tgtagcctct
    17281 gctaagccaa caacactatt gtcattaaga cctaggttaa gaattgtatc catcattcct
    17341 ggcatagaga atactgcacc agaacgaact gatactaata atggattctt attgcatcct
    17401 aatgttttat ttaaatcttt ttctaaagta gctaaatgct cttctatttc ttttattatc
    17461 tctgctctta tactttcatt gttaacataa taatcattac atgcttctgt tgttatagtg
    17521 aatccaggag ggacaggtaa gcctatctta gtcatttctg ctaaattggc acctttacct
    17581 cctagtaaag atttcatgtc tttgcttcct tcaccaaaac tataaacata cttagtttcc
    17641 attgttaaat cccccattaa tctttttatt ttaatttata tcatttttat taatagacat
    17701 tattaaattt ctatttcttt gtatatcttt agaccatttt ctttcattat gtctaaaatt
    17761 atacctgctg tttcttctat tgccttattt gaaacgttta ttactgggca tccaattctt
    17821 ttcattatct cttctgaata atctaactcc tgaagtattc tttctaaatt agcgtagttt
    17881 gctttactgg acaatcctaa agcttttaat ctttgggttc ttatctcatt cagcttttca
    17941 ggtgaattag taagacctat tattttttta gtatctatct caaacacttc tttaggaatt
    18001 ggtatttctg gaactaatgg aacattagct acttttatat ttttattagc taaatacata
    18061 ctcaaaggag ttttagatgt tcttgatatt cccactaaaa ttatgtctgc ttgaagaaca
    18121 cctctagggt cttttccatc atcatatttc actgcaaatt ctatagcttc aactctctta
    18181 aagtaagatt catctaattt tctaattata ccagcttctc ttttaggttt tcttcctgtt
    18241 ctcttgctta tttctcttag tatatctgtc attaaatcta tacaactaag accttctctt
    18301 tcgcaatatc tttcaacaat actgcataat tcttcatcaa ctaatgtata tacaattaaa
    18361 gcgttttcag cttttgcatt ctccaaagtt tcaagtagta ctcctttatt aatcatgtat
    18421 ggaaatcttt ttatttcata agtttcattc acataaaact gagacataca tgcctttgca
    18481 acttgttgtg cagtctcccc tactgaatct gatactgcat atataattag gtttttcacc
    18541 agcatacctc cttaattgtc aactatttct aagaatagct tagttatgtt ggtttttgat
    18601 attctcccaa caactctcat atgatttttg tcttctccct tatattcaac aatcggaatc
    18661 gaatctactt catgttctat tatttttctt gaagctaata aaacacttgc tcctttagtt
    18721 aaagtgacta catttggagt tcttgtcatt atcataccta ttggcatttt atttatatca
    18781 gaacctccta tagttgcttt tagcaagtct tttctggaaa caactccaca taactcttca
    18841 ttctcatcta taataactat actccctaca tcagataaaa acatagtgac tattacatca
    18901 tatatacttt catccttctt agctagtaca ggcatgctca ttatatcctc tactgttttt
    18961 tcttttacac ttttaccaat taaatttatt tcactaactc ctgaataaaa atatccaact
    19021 tttggtcttg cgtctaatat tcctgtcatt gttaatatag ctaaatcaga tctaagtgta
    19081 gcacgagtca cattcaagct ggaggcaata ctttcactcg ttattggttc attttcctta
    19141 actatatcta taatttttag ttgtctttca ttaagctgaa taataatcac cttctttcat
    19201 tgtgctatac tttttatctt ttcgcatctt atatagtata ttatataact atatatacca
    19261 ttctgtaaac agatttttta ttgaatacga tatatttttt actaagttct ctcgcttaaa
    19321 gatatttatt atatattaat gggggatatt tctttaatta atagaactat attagtatta
    19381 cagttaatat tataatacat aattggtcat tttaattcat tttatattaa aatttttaat
    19441 aatattattt caatgtgaat ataaaattgc agaactaatt caaaataatt tttacgacta
    19501 caaataacct ataatatact tttaaagaaa gtatcctaac aagaatatat aaaaatttaa
    19561 aagggttgat ttaaaaataa ccatcaaccc tttttactaa tatctattta tattaccatc
    19621 aaatcttacc caaatatttt ttcttgcaat tgtcttaaat gatataaagt agtatctttt
    19681 tctatctcta ccatatcgta agttataact tcaccttttt taatatcttt tacaacttta
    19741 gtctttttac ttatcaaacc aataggtaca gcattcatag cctttgctac atcgtatttt
    19801 tctatagtac catagcatgt atatgctcca tagccatcca taaactcacc ttttttcaaa
    19861 tctttcttag ctatagtcat aacttctgct actagtccag ctttaggtac tattgtagcc
    19921 ttatggtcta aaactgccat agctgctgat aaaggagtct ctaaactaca taaatgatat
    19981 ggtctatata atatgtaatt aggtccatca cccatactta aatattttaa ttcatcatta
    20041 actgctttta atttatgggc tactactacg aaaactccag gtgctatacc atttacaaaa
    20101 tcaactacac cgtaattatc taatactcca ccttcgcttt ttaatgcata tttcttaggt
    20161 acttcattaa ctgtagcttc aataccatga ccacctctta catcaggtac aaatccagtt
    20221 gcattacaca ttaaagccat ttctaccatt gttttagttc cttctttaaa agaagctatc
    20281 atatgaggtg aagctccttt tctttctgct tcttctctaa ctgtatcagg attacaatct
    20341 aaatctaatt tattattttt acctttacct atcactctaa cttcaaaccc cattgcatct
    20401 gcaaaatcaa ataattccat tactgcacct ggctcatctc ctgcagaacc tgtaaatatt
    20461 actccagcat catctgctaa ttttttaagt attggtccaa caacacaatc agtttcagca
    20521 tttaacataa ctatatgttt tttatttaaa atagagttta atgctatctc tgcaccaatt
    20581 gcaatacccc cagttgcatc tataactaca tctattgact tagttttaca agccacaaga
    20641 aaatcattac atgtcaatac ttttccttct tgtaatttta tttctgcatc cttttcattt
    20701 gttacattat ctataatttc ttcatctatt cctgcatcag taaaagcttt atgagccaac
    20761 tccaaatcta tatctacaac aatagaagct tcaatacctt tcatatttgc catttggctt
    20821 accattccat ttcccatatg cccagctcct ataagagcta cttttatttt tttaccttcc
    20881 tcttccaatt ttgcaagttt tctgtttaaa tctaacatac caattcctcc tgttataata
    20941 attttatttt caaattaaga aatagttatt aaatctccaa tagttatatc tggatttcct
    21001 atttccacat gtatttctcc tggtaaattt acttcacatt ttccatcaaa tttgattgta
    21061 caatgcccaa tttctctaag agtcttctga gcaatatcac caactgaaac tatacaataa
    21121 tctctattcc ctatagtaag tgtatctcct atttcaacat cactttttaa cgttgctatt
    21181 gaatgaatta cagatatatc ctttaagtcg tcatcattaa tggtttcatc atatataata
    21241 agacaattgc tttcatccat taactcttta actaaactgc ctatcccact tatcttaact
    21301 tcatatttca tgacattcct cctgataatt tatatttata ttgagttaat taaaagaaac
    21361 atttattttt tcttttataa attttatagc ttgtacaata ctctcttcat ctttaaattt
    21421 ttgctctgca ctatatatat ctaatccttc tatttcttca atctctttaa atttagccat
    21481 tactgtacgc ccttttaaaa tttctccaaa ctttataaac ccatctgaat ctgaagatat
    21541 aacggctata cttcctttag aaaaatagct tttctttttg cctgtagaca ctatatcacc
    21601 ctttttttta gctctattta aagttttaaa atacaattta ttctgcttca ttataaatat
    21661 agtatttaaa atataagcaa caaataaaat cactaataat ttcatattta tacaccttcc
    21721 aaaaatcaca ttatttttaa atctgtataa caactataaa tgctgtacaa tagttatata
    21781 aggtttttaa gtaacacctt tttaaattct aaaaaagttc tacatttact tatcttattc
    21841 gttaatttta catcttggcc tatctttaaa acttcttcat aaatttttac taataagtct
    21901 gagtctatct tattctcaca tggaaacatt gtcataagaa ttatttttat acttctattt
    21961 gcatattcta ttggttcttc taaaattcca actgccatta aaaacttatc tgatttttca
    22021 tttacagaat gaggaaataa taaaccttta tcaaatactg tgggagattt ttcttctcta
    22081 ttgactatat tttttctaaa cttatcatca atgcatccca aatccataag atggtccatc
    22141 attttttcta atgaagcaag tatagtcttt tcatttaata tcataaattt atcttcatct
    22201 aacaaattat ttattagtaa atttgtagaa ttagtagtgt caatattccc ttctcttagg
    22261 cacaatactg tttttaattg ttctcttagt ttgttttcat caaatattgt atttattttt
    22321 aatactattg tatttatatt tgatgtgtct aaatcaatag ttgtaaaaac tatatcgtat
    22381 tcatctaagt taatatttct caaattaaaa cttgaaagag tatcaatttt aggattattt
    22441 cctatcagtt tttctactct tattttcaat agttttgctg ttcctagacc tgtactacat
    22501 ataattgcta ttttttttat tgaatagaat ctactgctat ttctttctaa atatccactg
    22561 aaatggattg ctatatatcc aatctcatct tctgaaactt ctaagttata ctttttctct
    22621 attacttttc ctgctatttg tgctaattta aatggaagta tataattttg cttaatctct
    22681 tctaacaaaa cattttttaa ctttatatta aataatagcc tgtttaaagt aaaactaaga
    22741 tgatatccta gacctactct taattcatcc tcatttataa aaatgcccat atcgacatat
    22801 atttgattaa atatattttc catcaactca tcaatgtttt tactaattct actactattt
    22861 aaagcacatt ctgatgctgg tgcatttcca ctaactaacg gtatagttaa ataaataatt
    22921 tcttcatcat ttaaagtaca ttcaaacatt cctgatatta tatgttttat ttccctagca
    22981 ataaagtatt catcatatga tttaagtaaa tcaaacttta catcataatc ttttactttc
    23041 ttttcttctt ttactctata gactaaaact actatgtagt taataacttc tcttaacatt
    23101 tcatctgtaa cataaaaatt atttttttta aataaagtca atagtttttc ttctaaattt
    23161 atgatttctt cttttttgat tcctttaaaa tactttgaat tactgaaatc tttccttgag
    23221 tttttataca actgatttaa tataaacagt ctaatatcaa gttcatttcc atttaatttc
    23281 atacctgtat tctgtttttt aatcaagttt aaattatatg aagccaaaac tttttctaca
    23341 tactggaaat catttactaa agtagttctt cctacacaca tctcatcagc taaactatca
    23401 agtgtaataa atccatctag ttctatcaag taatttagta taaactctac tctatcttct
    23461 tttgaattta atgaaaatac attttttcta ttcatatcaa taatcttatt gagtatctgc
    23521 tcatctttta tttctagttt atagccttga ccctttatat atttgattac tgctatatca
    23581 ttacctaaat ctttattcaa ttgttttata tacgtcctta cacttctagt tgtgacattc
    23641 aattcatttg ctattgagtt aatactcaca aactcttttt tactacacat aatcaatatc
    23701 ttaaatatct tgcggtcaat agaaggaatt ttctcagtta cactcatttt gtatctcctc
    23761 cttgatttca ttctagtaca aatttgaaac caaattaata cataaaattt cactttaata
    23821 aaggaaaatt tagtattaat ctaactcgat aattacagct aattaatagt ataaaagcta
    23881 gtctttcatt aacaaaaaat cttgactagc ttaaatttat atttacaatt ttattaatta
    23941 attccaagcc ttatattgac attaaatatt atctcaatgc aaatactgca actccatatg
    24001 caataataac agctattgga ccagttatta aacgagagta aaataaagct ggaacaccat
    24061 actctacagt ttctggttct gcttctccca aacttaatcc tactggtaca aaatcacatc
    24121 cagcttgacc atttattgca aataaagctg gaagtgctaa atatgctggt attgcaccaa
    24181 gaccaatttg tgtacctaca agagtcccta ctacttgagc tataactgca ccaggtccta
    24241 gtattggtga taagaatgga agtgtgcaaa ttactgatat aatcaataat ccaccaatat
    24301 tacctgcaag tggagatata actcttgcaa tccagtctcc cagtccagat gctaaaataa
    24361 ttcccataag catacttaca aatgccataa atggtattac gttattcatt accatttgga
    24421 tagtatctcg acctgcatca taaaattttg atactacttg ccctgcccct tgaccaatag
    24481 aaagtattat gttcttttta gcatattcac cttgtgcttt tgacttaacc tcatcataat
    24541 tatcaggctt tctaatagaa ctcttatttt cgcttttatt ttcttgagat ttttgtggca
    24601 tatcttcccc atctacaaca cttatacagt taggattaac atctgataca taatattctt
    24661 ctgttataaa ttttgctaaa ggacctgttt ttccaactgg atttacattt attgtaggta
    24721 tttttttctt tggataaact ccacatctag cagttccacc acaatcaata ataactactg
    24781 ctacttcttc atcagaaact ccagttttaa atccatctac aatttcacaa cccagtagtt
    24841 cttttatttt taatgttact tcatggatac cgccagcagt cattgatagt atcttatttc
    24901 tattcccttc tttttttata tacaaaggac ctccccagcc tgaagttccc ttttctattt
    24961 ttaatatttt attctcctcc attttatcta cctcctaagc cttatttgtt gctctatttt
    25021 ttcttgttag aaaagcatac attttttctg ttactatacc tcttataaaa attacaatta
    25081 gaccaactat aaaataccac aatgctagtg tagtagtttc tttacctaaa gtagtcaaac
    25141 ctgcagatat tcccaaccat acaaaaagtt ctcctgcatt tgcatgtgga aaaagacctg
    25201 taattggatg tacaaatgaa actgctgcat cataaaatcc tgctttgtgc tcttctttta
    25261 aaaatctacc aaatgtatag cacataggat ttcccaagaa aaatactgat actaatggaa
    25321 gtagaatata tcttgtaaaa gagttctttc ctagcttaga agcccaatta ttaactcttt
    25381 cctcaccaat tatcttaatc aaagagttaa tagctaccat taatacaatt agcgttggaa
    25441 gagtacctga aacaagacct ataaattgtt ctcccccttt ctgaaacaaa ccgataaacc
    25501 actctgcacc tttacttaga cctgtaataa cgttttccat aaaattataa cctccctata
    25561 atatctttaa atttttaatt ttactgctta ccataaattt tacaaattac atcttttttc
    25621 tgtactatat gctaatattg taaatg
//
LOCUS       DAEORM030000054        25263 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.054, whole genome shotgun sequence.
ACCESSION   DAEORM030000054 DAEORM030000000
VERSION     DAEORM030000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 25263)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25263)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 25263)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25263
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.054"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            complement(<1..308)
                     /locus_tag="KRH23_002906"
     CDS             complement(<1..308)
                     /locus_tag="KRH23_002906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ORF6N domain-containing protein"
                     /protein_id="HHS5226183.1"
                     /translation="MNNLQVIERNNERVLTTQQLADVYETDARNISNNFNNNKDRFIE
                     GKHYFLLQGDDLKNFKGIHTEYENLKFTSKMYLWTERGANRHCKILDTDKAWEQFDNL
                     "
     gene            complement(301..537)
                     /locus_tag="KRH23_002907"
     CDS             complement(301..537)
                     /locus_tag="KRH23_002907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HHS5226184.1"
                     /translation="MNKLKDFRIQKGLSRNQLGAELGLTSRYIAFLENGERVPSLNTA
                     VKIAAYFNTSIEYIFLKNNCTKSTFKEKGAEKYE"
     gene            682..1047
                     /locus_tag="KRH23_002908"
     CDS             682..1047
                     /locus_tag="KRH23_002908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHS5226185.1"
                     /translation="MIGYRIKELRKEKDITQKELATFLGLTPKMISFYEKEERFPPHD
                     IILKLSDFFNVSTDYLLGKVNVKNIDNLSELELIENLNFSDDIKEALKLISELSPSSQ
                     EKMFKIAKVFLEEELNEKK"
     gene            complement(1062..1202)
                     /locus_tag="KRH23_002909"
     CDS             complement(1062..1202)
                     /locus_tag="KRH23_002909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226186.1"
                     /translation="MEKSKKLLIDTGDTLNKLRENNSEKLEKYIELLKEYYKQENKKE
                     RE"
     gene            1698..3146
                     /locus_tag="KRH23_002910"
     CDS             1698..3146
                     /locus_tag="KRH23_002910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SAP domain-containing protein"
                     /protein_id="HHS5226187.1"
                     /translation="MSILNLFRKNKNKNNVDCNEKSNESKQSYNDSTTLSLECNSNSP
                     HNIEVKNEINKVLNVSCNDTTNLYELEKQAREKSDALYDIHTNSINKFNPQNNILETD
                     TKPLTSIEKSFLKYIIGENIYEPYIATYWTYEYNINYSYLISKFFNMDYLKISNYIED
                     LTKLTVSELKEILKSNNIKSTGKKAELIERIEKEISCKDLSNFFNSSNKYYALTDKGK
                     ELLKDVRKSVTKNTDLEDQCLELIYIDKYEEAYDLICKYESSKNIQRGININWENHKI
                     TPMKIESYKAIKELDINLKDTLLDNIIKSSYILCDMLGNNSKTSILVKRLAGEKIDNI
                     EINNAINSINDVIYNHSTITYNANDSINNKNLHYMDIVKNNKSIPFEVNNKNYNFKIN
                     ENEIYFFNILKIKMYENELKNNFVFDRMSDGAFNVFDTSDNFIGKVKLQGRKKWIMYM
                     KNEFGSEHIYGELIHLIDGIDAWIKYSKEYLK"
     gene            3417..5081
                     /locus_tag="KRH23_002911"
     CDS             3417..5081
                     /locus_tag="KRH23_002911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4041 domain-containing protein"
                     /protein_id="HHS5226188.1"
                     /translation="MNNENEQLKSDLLINDEKIKNLNFKIPWYYSLWTISILILSTFS
                     TYSISFIVAIIFLFKRNKIMKKHKDSISILLSDVEKINNKYILLNDEIKMKEKHFEDL
                     CESNENKLKELSNLLDKKKVEIDKFDSENQDKFKLIEELKIEKERLDNLIKDKNILKD
                     NINTLNSHLEELKNEREELRDINTTLKNKKEELKRLSEELIQTEDEVLLQSFGLYNPK
                     YDFENSDEYMEKLKEIREMQKLLIRNKTGVKYSDSWTVDGSVQKGRTMTNQNIKTALK
                     LFNSECDIAMSKVSFKNIDSIEKRIRKAFTDTNKLNTSNKVSIKENYLNLKIDELYLY
                     YEYLQMKEEEKEEQRALREQMKEEALVQKEIENQKRKLKKEELQFKNELLRLKSTIPE
                     DENDKLEWEQKINSIEEKLALLSKDLDDVLNREQNTRAGHVYIISNIGSFGENIYKIG
                     VTRRLDPTERINELSSASVPFKYDIHATIFSEDAPKLESALHKAFDNKRVNKVNNRKE
                     FFKVTLDEIRTEVEKNFDKTVEYTKLAEAQEYRQTLKIQELNNKLA"
     gene            5595..6713
                     /locus_tag="KRH23_002912"
     CDS             5595..6713
                     /locus_tag="KRH23_002912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HHS5226189.1"
                     /translation="MNIKSAFIRKRGEKFHVYVEYIEETTGKIKQKSYGSYEKKKDAE
                     KHLIEIKSTINNNKFITPNKITLVERCYKYIIANEKNWSPYTTVNRKSWVNNYIEPFF
                     KDIKLIDINPSLLQFFINKSFNNSTSSSAKVRYNFLSSVLKEAYRLKEISENPCDFVK
                     LPAQNVTYEIEIYNREETLLLIEKLKDSLIEIPILLMLLLGLRIGEVAGLRWSDVDLD
                     NSIININQILIYANSKITFKEPKTAKSKRTLSVPKELIEKLKIEKLKQNKMKLQGTLE
                     NENNLVCLNTNLKPWIPTALSKTFHNFIKRNNLRNIRVHDLRHTNASLLLLGGTNMKV
                     VSERLGHTDIKITMNRYSHVLEEMDKEASDNLSKLLFK"
     gene            complement(6864..7544)
                     /locus_tag="KRH23_002913"
     CDS             complement(6864..7544)
                     /locus_tag="KRH23_002913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HHS5226190.1"
                     /translation="MQTKILIIDGDKDNCQKLKGFLEEKGISIDLAYNCEEAIGKIFS
                     NKYDLIFLEIILSDGDGWTLCKKIRNVTTCPIVYMTYINEDQSILNALNSGGDDYLIK
                     PLNLEILYAKVKAILRRMNSYVNNNENNTKLEEYNRTSGVIKLEDKIIKLTPTENKLL
                     NFFIENPEKTLTTKEIYEHVWMNEYLEDNYSVVVAVNGLRKKIEKDYKNPQKIITIRG
                     AGYYFNKE"
     gene            complement(7594..9609)
                     /locus_tag="KRH23_002914"
     CDS             complement(7594..9609)
                     /locus_tag="KRH23_002914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HHS5226191.1"
                     /translation="MKKYNILKGTLIVLIVSLLAITGLNVLYKYDNKYTYKSIRASNG
                     ILTIDNDTFTKGKLVFLIDDWEFYNHKIFKPNDFTEQDIKPEYVFIGQYPDFSMRKGN
                     QSPYGNATYRMRIKNEGKDKLLSLELPEIFSASEVWINGEMVSKLGDVGTEKYRPKIK
                     NSVVSFIAKKNTEIIINVSNFSHYYSGLYYPPALGETKDISNMMFYRLLFYSIICFTT
                     FAIAIFSLSVWFLSNKSKIYLYFGCMCVFFAIHVSYPFVHLLGLPLVSFTYAVEDLSY
                     FMVVLCIICINGSISKIEENKVYRFLILPLGITMSIISIVIPIILLPYDMYFVNIYGK
                     LIDIYKYIVFIYILMSSLVSIYKKTCSEHISSYILVSVNTVFGISILFDAVTSNRFEP
                     IFTGWQTEYCGFVIVILFSVMMINRNRIIIKENEKLTRNLEHEVEVRTNELTTLLNER
                     KRFLADVAHDLKAPVSAIQAFIDLIKVGNIHVDEETRTYLYAINQKSNEVQNRVRSLQ
                     EFTSQDKSIGISEKICLNNFIKEIYENNLPDTQACGVNFETYVLEKKIYAKINKEMLT
                     RAFENLIYNALTFTPFDGKIILSMDKEDGFAIIKISDNGKGIPPENIPKVFDRFFTER
                     DNNEPKGQGLGLYIVKSIIREHGGEIFVDSELGKGTVFTIKLSLCFL"
     gene            complement(9681..10358)
                     /locus_tag="KRH23_002915"
     CDS             complement(9681..10358)
                     /locus_tag="KRH23_002915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HHS5226192.1"
                     /translation="MYNLLVVDDDVDILNINQIYFSNIGFNVYTSETAKDAMDIVESI
                     VLDCIILDISLPDIDGYKMCNDIKEKVNIPIIFLSNYEHEEEKVRGFLAGGDDYITKP
                     YSLKELELRIYARMRQYKNITSVPNVLKFSALVINVNSRKVTFDGESIDLTTMEFEIL
                     LFLAENKEQVFSKIEIYNQVWKMPDIGDQHTVQVHIAQMRKKINSLSREHQYIQTVWG
                     KGYKFVP"
     regulatory      complement(10938..11021)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF01786"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cyclic di-GMP riboswitch class II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01786"
     gene            complement(11254..12096)
                     /locus_tag="KRH23_002916"
     CDS             complement(11254..12096)
                     /locus_tag="KRH23_002916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein"
                     /protein_id="HHS5226193.1"
                     /translation="MFKKKIGVLLASTMLVGALAVGCSSNSGGSGDSGDSSKVSVSGS
                     TSIGPLMETIGEKFQEKNQGVSVEVQQIGSSGGIKNAIEGTSEIGMSSRDLKDEEKSA
                     GLKETKIAIDGIALITNTANSVKNLTMDQVKGIYTGKITNWKEVGGNDAPIVIVSREE
                     GSGTRDGFQEIVGFDSEELTKDAQISDGSGNIKTTVEGNENAIGYISFGYVDEKVNSL
                     KINDVEATDANVIANKYPISRPFILVNKEDGLSEKGKALIDYILSDEGQALVSEKGFI
                     KVNQ"
     gene            complement(12348..14132)
                     /gene="pepF"
                     /locus_tag="KRH23_002917"
     CDS             complement(12348..14132)
                     /gene="pepF"
                     /locus_tag="KRH23_002917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HHS5226194.1"
                     /translation="MGTDRSTIEEKYKWKIDKMYSSKEEIEKDISKVKNLIQEVKEYK
                     GKLSESKENLYKVLNISENASRIVQNLYVYTHMKQHEDTRINDNQGRATKTEMLSTDL
                     GVATSYIVPEILAIEENKLSEYLKDEKLSFYTKYIKDILRDKPHTLSEREEEILAATS
                     ELSTIPENVYDMLAYADMEFPEIEDEEGNKVKLSHSNYSLFIKSKNSRVRKDAFEGEF
                     STYEKYKNTFASTLYGGIKSEIFYAKTRKYNSAIEASLFSDDVSLDVYNNLISAIDKS
                     IPNLNKYVELKKKFLGLNEIHMYDLYVPLTDKFDMDIPYDKAQDIILEALKPLGEEYL
                     KVIKSAFDEGWIDVYDNEGKKGGAYSWGSYDSHPYILMSYKNDLNSLFTLVHELGHSV
                     HSHYSRTSQPFLYSDYKIFVAEVASTLNELLLINYLLENSKSKDETIYLLNYYLEQFR
                     TTVHRQTMFAEFEKIVHQRVESGEPLTADEFTNIYYKLNEKYYGKSAIVDKQIGIEWA
                     RIPHFYSNFYVYKYATGFSAASALSQQILSEGSTAVDRYINFLKSGGSEYPLEQLKSA
                     GVDMTKKESIEEALNVFAELVNKLEKEL"
     gene            complement(14198..14863)
                     /locus_tag="KRH23_002918"
     CDS             complement(14198..14863)
                     /locus_tag="KRH23_002918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HHS5226195.1"
                     /translation="MIDIGSKEIAIRLLLALIIGGIIGLEREKIRQFAGFRTHILIAI
                     GSCIVSITSIQLFFDYNLYTNADPARMPAQVLSGIGFLGAGAILKNKGGVKGLTTAAG
                     MWATACIGIAVGYGYYELAILGGLFVMIALFVLRIINTFLFSQEKNVLILKLSNLDSI
                     PFLYDKFEKNQLIVRNMEIECRNEEYWKVNFFVSYAKRIHLHDVMKEINMIEGVINVD
                     YLD"
     gene            complement(15014..15175)
                     /locus_tag="KRH23_002919"
     CDS             complement(15014..15175)
                     /locus_tag="KRH23_002919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartyl-phosphate phosphatase Spo0E family
                     protein"
                     /protein_id="HHS5226196.1"
                     /translation="MANNELEALKNEIEAVREEINTYIEYPEIFQEELVESSKKIDIL
                     INKYMYLSK"
     gene            complement(15253..15762)
                     /locus_tag="KRH23_002920"
     CDS             complement(15253..15762)
                     /locus_tag="KRH23_002920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gx transporter family protein"
                     /protein_id="HHS5226197.1"
                     /translation="MKTRKMTFLGLMIGYSLALYVLETYIPNPLIVIFPGAKLGLSNI
                     ITLISLMLLGVKDTVIIVTIRVILSSIFAGPLSYLLFSIGGAYLSLLFMYLASKIKDL
                     SLIGISIIGAIGHNIGQLIVASLIIENILAIGYLPFMLMASLVTGMFVGLVSRYTIPK
                     LKHFYSKFY"
     gene            15968..16186
                     /locus_tag="KRH23_002921"
     CDS             15968..16186
                     /locus_tag="KRH23_002921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046914 - transition metal ion binding
                     [Evidence IEA];
                     GO_process: GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FeoA family protein"
                     /protein_id="HHS5226198.1"
                     /translation="MTVYDLKIGEKGFINSIDGDIKLSKRLLALGCINSTEIEVKKVA
                     PLGDPIIIRFRGFDLAIRKSDAKNISLQ"
     gene            16204..18150
                     /gene="feoB"
                     /locus_tag="KRH23_002922"
     CDS             16204..18150
                     /gene="feoB"
                     /locus_tag="KRH23_002922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0015093 - ferrous iron transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HHS5226199.1"
                     /translation="MINVALLGNPNVGKTTVFNLLTGSNQYVGNWPGVTIEKKEGFLG
                     KEIKVVDLPGIYAMDTFSNEEKVSKSYLENEDVDVIVNVVDASNLSRNLYLTTQLMQF
                     NKPIVILLNMLDIAESKGVNIDAKKLSEELGVIVVPIIAKKKNGVDRIEEEIKGATQK
                     AFIYQKNFGSETETYKKLESILSRCTKTTYTQKKSISDKIDNIVLNPILAYPIFIGVL
                     FLLFKFTFDWVGGPLQEGFASLIEAYISAPVSDMLSNSSPWFKSLIVDGIIGGVGGTL
                     PFFPLIFTLFFGISLFEDSGYMSRTAFLMDKVMRKVGLSGKAFIPIVMGMGCSSPAIM
                     ATRTLESEKDRRVTALIAPLMTCGAKLPIYALFVAIFFPHNAALVTTSLYLVGIVMAI
                     VVALFLNKTAFKTEAEPFILELPEYRIPTIDALIKNTWNKSKGFLIRVVTVMFAMSVV
                     IWGLSSFNVFGYTEDINVSFLATLGHIISPIFKPLGFDDWRTSVAILSGLGAKEIVVN
                     SLNILYGNLTVVLPTIFNGVTAYTFLIFTALYTPCIAALATMKKEYGNKMMFTSFAYQ
                     FILAWIMAFIVKSIGGVLFMGNSIMEALIGGIIIVLALFILFNKFKSTKNGNVCSGCS
                     ICSGCPSANSCSSKEDSNKKNNAH"
     gene            complement(18310..19365)
                     /locus_tag="KRH23_002923"
     CDS             complement(18310..19365)
                     /locus_tag="KRH23_002923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HHS5226200.1"
                     /translation="MTIQDYMLETPVRMREIISNADSLFNEVKRTNLKKIIITGSGTS
                     YHSGVQVQPYLQNLLDIDVVKMYPFMITEDTFKFDNENTLVVGVSQGGSSYSTYNAMK
                     LAEDKGCKIASMAGCKNALIDEISDYILTVNCGEEKSGAKTKGYYCTKLNLMLLGLQI
                     AREKGIISSEKYNEEINKILDAINRFEAVYKLSKQWIERNKEKLVNSKEIRIIGHSDI
                     YGDTLEAALKLLETMRIPVTGYEFEEFIHGIYNAINSDSTIFILDTGKEPRVTKMIDV
                     LSGWTENVFAIGRDVTENDKNLKIDITDNPYYQTFNFIVPIQLICGEIPTLRGVDPSV
                     PKDTRFHMKLGSKKLNK"
     gene            complement(19413..20213)
                     /locus_tag="KRH23_002924"
     CDS             complement(19413..20213)
                     /locus_tag="KRH23_002924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HHS5226201.1"
                     /translation="MNKLTKKELRSMFWRSFALQGAFNYERMQNLGYCYSMLPAIKKL
                     YNKKENQAKAIERHLEIFNTTTVVVPAILGITAAMEEENANNPEFDESSISAVKTALM
                     GPLAGIGDSLFWGTFRIIAAGVGVSLAKEGNIFGPLLFLLLYNIPAFALRIFGLKYGY
                     QVGVNSLERIQREGLMEKIMSMATTVGLFVVGGMVATMLSITTPLKFNLNGAEVILQD
                     ILDKIIPNMLPLTFVFVIYYMLKRKVSVTKLTIGTIVTGIALHAIGLL"
     gene            complement(20206..20997)
                     /locus_tag="KRH23_002925"
     CDS             complement(20206..20997)
                     /locus_tag="KRH23_002925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HHS5226202.1"
                     /translation="MLVQATMLAIIAGVGILDGRIFGQSMLDRPIVTGMLVGLVLGDI
                     KSGIMIGAQLELIWMGIAGIGAATPPDVVTGGVLGTAFAILSGNGAEVALAVAVPVAV
                     LAQSLGVLVRIINSYFSQKAVFYAKQADFKKVTIMMWLPVILFFLSTSVPTFLAIMIG
                     ADKVTALINAIPKVILDGLGVAGTLLPAVGFALLMDMLLSKKMSVFFFIGFLLASYGG
                     LDITAIALFGVCVAFVLNFYINNKENNQNPQLAINTLTEGEIDFE"
     gene            complement(21037..21459)
                     /locus_tag="KRH23_002926"
     CDS             complement(21037..21459)
                     /locus_tag="KRH23_002926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HHS5226203.1"
                     /translation="MKKFLIATHGELSRELVDTSKLIIGSLTNIEYFCMTTDKSTDDA
                     EKEIRSILSNNKDSEEFVVLTDVFGGSVANICTNLLLQGFKFELLTGVNLPMLLSILL
                     LVEEDTKLIVKSGLEEAKNGIVYVNELLENQNKIKNVM"
     gene            complement(21475..21954)
                     /locus_tag="KRH23_002927"
     CDS             complement(21475..21954)
                     /locus_tag="KRH23_002927"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HHS5226204.1"
                     /translation="MVSLMRIDDRLIHGQVAYGWATSLGINVILVANDEAKNDQMKAM
                     SLNLAKPSNVTLYIRGVEESGEIVEKFASSKKSNVLVLVKNTKDALVVAKNSGGVLKE
                     INVGGLRYEEGKKKLTDLVAVDDDDINNFKQIGDLGIDIEFRMLPRDKKKQLSNLIK"
     gene            complement(22086..24842)
                     /locus_tag="KRH23_002928"
     CDS             complement(22086..24842)
                     /locus_tag="KRH23_002928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HHS5226205.1"
                     /translation="MRDEILSFVNECVLFNNFDELKKESGIITEDIVKKFNLSRTQSS
                     RLLNDLVKSDNLIKINSRPVIFLPKNKINDVVGPTKKSIYENLDELKNECKLLKQETV
                     FNSIIGYDNSLKEVIEQIKTAVLYPNGGLTIMLTGESGVGKTFLAKIIYKYSVSSNVL
                     EKNSPYNVLNCAQYYNNLELLSSLLFGHVKGAYTGANESRAGLIEQSDGGVLFLDEVH
                     RLNSEGQEKLFTFMDTGTFSRIGENGVIRKARVRLIFATTESLSEFLQTFLRRIPINI
                     YVPNIEERGTIEKRKIVEHFIYEESKVLGLPIEITQITLNAILKIKFKGNIGECKNVI
                     KYACGRAYAKNQRRNGNIFVTLQDLPRNLYIENVDVFQFQSGKSKSIIFSPKQFSIEM
                     SNGRNKRNIIYQSFIKCLDYFDRLEKNEITKEKFSKKSSNLMIRLMDNLVFSNNDENN
                     NVLMELIISIMQDIFRNLEVNNNIKYDGNNVLAFSSYLYLKDESYQLSDEYKALENKL
                     LIYLKKESYKEYSIISKISTLITNRLDMYLNNVDTIIMIIFIKSTIIRMKFNQVNATI
                     IAHGYATASSMANVCNRMLGKNIFTAIDMPIDATIADVSKQMSRYLEGDRIKNGLIVL
                     FDMGSLNLIYEDLKNKINSPMLFIDQISTISALEVGNLLMQGKNIEEIAEIMDEETKP
                     NIQLYYPQKNKEYAIISSCFTGIGTAIKIQHLLSESLIGIVDVKIIPYDYDSLVSMGD
                     KEPVFEMYDVMAIVGTANPNVNGVDFILLEDIISGKGEDDVFRIFSRVVENEKIKNIN
                     DSIVKNFSLIRVIDSLTILDSKKIIERIEEGINAIENIQKKKLSNDKKISLYVHLSCM
                     IERLVRQTEIEEYTDMDLLIKNHHSEVKLIKNAFSVLEKSYSVQIPISEIGYIYNIIY
                     GLPQ"
BASE COUNT         8879 a         3943 c         2873 g         9568 t
ORIGIN      
        1 tctaagttat caaactgctc ccaagctttg tcagtatcca atattttgca gtgtctattt
       61 gctcctcttt cagtccaaag atacattttt gaagtaaatt ttaggttttc atattctgta
      121 tgaatacctt taaaattttt taaatcatca ccttgcaata aaaaataatg tttaccttca
      181 ataaatctat ctttgttatt gttaaaattg ttgcttatat ttcttgcatc tgtttcatat
      241 acatctgcta gttgctgtgt agttaaaact ctttcgttat ttctttctat tacttgtaag
      301 ttattcatat ttttcagctc ctttttcttt aaatgtactt ttagtacagt tgtttttcaa
      361 aaaaatatac tctattgaag tattgaaata agctgctatt tttacagctg tatttagaga
      421 cggtactctt tcgccattct ctaagaaagc tatataccta cttgtaagac ctaattcagc
      481 tcctaactga tttctactta gtcctttttg tattctaaaa tcttttagtt tattcatttt
      541 ttcaccttct tttactttat cttatgtact aatagtacag tactattagt acattgtcaa
      601 tagctttttt aaaaaaaatg agctataatt gataattaag aactaatagt tcaatataaa
      661 ttaaaaaggt ggctaaataa catgattgga tatagaataa aggaattaag aaaagaaaaa
      721 gatattactc aaaaagaact tgcaactttt ttaggtctta ctcctaaaat gatttctttt
      781 tatgagaagg aagaaagatt tcctccacat gacataattt taaaattatc agattttttt
      841 aatgtatcta cagattattt gcttggaaag gtcaatgtaa aaaatataga caatcttagt
      901 gagttagagc taattgaaaa tctaaatttc tctgatgata taaaagaagc tttaaaacta
      961 attagcgaat taagtccttc tagtcaagaa aaaatgttca aaatagcaaa agtatttctt
     1021 gaagaagaac ttaatgagaa aaaataagaa agagaagaaa actattctct ttctttttta
     1081 ttttcttgtt tataatattc ttttaataat tctatgtact tttctaactt ctcactatta
     1141 ttttctctta atttgttcaa tgtatcccct gtgtcaatta gtagtttttt tgatttttcc
     1201 acacgccttc cccctactat cagaacttat gttcttattt ttagttaaaa ttcccaacaa
     1261 atttcaataa aatataacta tgtattttca tttctaaaaa tatttttaga ttattcaaaa
     1321 ttttcttgga taattatctt acttacataa taatactttt gttaaatata tgcaataaaa
     1381 aaaggggaat tgtaacaaaa aaatcgaatt ttgtagagtc ttggttattt tttccattcc
     1441 tgtgtattat taatcgtctt tttaattata attttttgta ttttcttgtt tatataatat
     1501 tttttattat ttaattttaa aatcttcgtt ttacttttta taccatataa atatagtatt
     1561 cttttcaaaa ctatttaatt ctatgttttt tcctaatata catagcattt atacagaaag
     1621 ttttatatac ttaaattgtt attgtcacaa agtagaatac actagaaatt aattaaatac
     1681 aaaaggagta attttttatg agcattttga atctatttag aaaaaataaa aacaaaaata
     1741 atgttgattg caatgaaaaa tcgaacgaat caaaacaaag ctataatgat agtactacac
     1801 tttcactaga atgtaattct aattcacctc ataacataga agtaaaaaat gaaattaata
     1861 aagtgctgaa tgtaagttgt aatgatacaa caaatttata tgaattagaa aaacaagcaa
     1921 gagaaaaatc agatgcttta tatgatatac atactaatag tattaataag tttaacccac
     1981 aaaacaatat attagaaaca gatactaaac cacttacatc aatagaaaaa tctttcctaa
     2041 aatacataat tggagaaaat atatacgagc cttatatagc aacctattgg acatatgaat
     2101 ataatattaa ctattcatat ttaatttcta agtttttcaa catggattat cttaagattt
     2161 caaattacat tgaagacctt actaagttaa cagtttcgga attgaaagaa atattaaaat
     2221 ctaataatat taaatcaact ggtaaaaagg ctgaattaat agaaaggata gaaaaagaaa
     2281 tctcatgcaa agatttatct aattttttta atagctccaa caaatattat gctttaacag
     2341 ataaaggaaa agaactgttg aaagatgtgc gtaaatctgt tactaaaaat actgacctag
     2401 aagaccagtg tttagaatta atttatattg ataaatatga ggaagcatat gacttaattt
     2461 gtaaatatga atcctctaaa aatatccaaa gaggaattaa tataaactgg gaaaatcata
     2521 aaattacacc tatgaaaatt gagtcttaca aagccataaa ggaattagat ataaatttaa
     2581 aagacacact tttagataac ataattaaat catcctatat actttgtgat atgttaggaa
     2641 ataactccaa aacttctata ttagtaaaac gtttggcagg agaaaaaatt gataatatcg
     2701 aaattaataa tgctataaat agtataaatg atgtaatata caatcactct actataacat
     2761 ataacgcaaa tgatagtatt aataataaaa atttacatta tatggatatt gttaaaaata
     2821 acaaatcaat accattcgaa gttaataata aaaattacaa cttcaaaatt aatgaaaatg
     2881 aaatctactt ttttaatata cttaaaatta aaatgtacga aaatgaatta aaaaataatt
     2941 ttgtctttga tagaatgtca gatggagcat ttaatgtatt tgatacttca gacaacttca
     3001 ttggtaaagt taaattgcaa ggtagaaaaa aatggataat gtacatgaaa aatgaatttg
     3061 gttcagaaca tatttatggc gaattaattc acttaatcga tggtattgat gcttggatta
     3121 aatattcaaa ggagtatcta aaataataaa agagctactt aaaatgatta aaactaattt
     3181 taagtggctt ttccttatgc tcaaaatact gataacatac ttttataaga atgttatatt
     3241 atttttctaa tttctgttaa cataccttta taatccaact aaattctttt aaataactac
     3301 cattttgttt tatttttacc tttttttgca aatatatgga aattgcacat aaaattttat
     3361 atacttaaat tattattatc ataaagtaga acaaaaaata aaaaaggagt tttgatatga
     3421 acaatgaaaa tgaacagtta aaaagtgatt tactcatcaa cgatgaaaaa atcaaaaatc
     3481 ttaatttcaa gataccctgg tattattctt tatggactat atccatacta attctttcta
     3541 cgttttcaac atactctata tcatttatag ttgcaataat attcttattt aaaagaaata
     3601 agataatgaa aaaacataaa gatagcatta gtatactatt atctgatgtc gaaaaaatca
     3661 ataataaata tattttatta aatgatgaaa ttaaaatgaa agaaaaacac tttgaagatt
     3721 tatgtgaatc aaatgaaaat aagttaaaag aattatccaa tctattagac aaaaagaaag
     3781 ttgaaattga taaatttgat tcagaaaacc aagataaatt taaacttatc gaagaactaa
     3841 aaatagaaaa agaaagactt gataatctta taaaagataa aaatatactt aaagataata
     3901 ttaatacttt aaattctcat ttagaagaat taaaaaatga aagggaagag cttagagata
     3961 taaacacaac tttaaaaaat aaaaaagaag agctaaaaag attatcagaa gaattaatac
     4021 agactgaaga tgaggttctg cttcaatcat ttggattata taatccaaaa tatgattttg
     4081 aaaactctga tgaatatatg gaaaaattaa aagaaataag agaaatgcaa aaactattaa
     4141 taagaaataa aacaggtgta aaatattctg attcttggac tgttgatgga agtgttcaaa
     4201 aaggtagaac tatgactaat caaaatatta aaacagctct taaactcttc aatagtgagt
     4261 gcgacattgc tatgtcaaaa gttagtttta aaaatattga ttctatagaa aaaagaatac
     4321 gaaaagcatt tactgataca aataaattaa atacttcaaa taaggtttct ataaaagaaa
     4381 actatcttaa tttgaaaata gatgagcttt atttatatta tgaatacctt caaatgaaag
     4441 aagaggaaaa agaagaacaa agagctttga gagaacaaat gaaagaagaa gctcttgttc
     4501 aaaaagaaat tgaaaatcag aaaagaaaac taaaaaaaga agaattacaa ttcaagaatg
     4561 aattacttag actaaaatca actatcccag aagatgaaaa tgataaatta gaatgggaac
     4621 aaaaaattaa ttctatagaa gaaaaactag ctttgctatc aaaagattta gatgatgtat
     4681 taaatagaga acaaaataca agagcaggac atgtatacat aatctccaat attggtagtt
     4741 ttggagaaaa tatatataaa ataggagtaa ctagaagatt agacccaact gagagaataa
     4801 atgaattaag tagtgcatca gttcctttta aatatgatat acatgcgact atatttagtg
     4861 aagatgcacc taaattagaa tcagctttac ataaagcttt tgataataag agagttaaca
     4921 aggtaaataa tagaaaggaa ttcttcaaag ttacgcttga tgaaataaga acagaagttg
     4981 agaaaaattt cgataagact gtggaatata caaaattggc agaagcacaa gaatatagac
     5041 aaacattaaa aatacaagaa ttaaataata aattagctta aatatattca aacaattata
     5101 ctttaataaa atattatttt tgaatatcta taccaatttg tgatataata atagcaagga
     5161 gataaaattt actttttaaa aggtgaattt ctctaattga ttagaattta aaagttattt
     5221 ctttaaatca cccttattgg cgtttgggtg attttttatt ttgtcatata tgaaagctga
     5281 tacaatacca gctactatac tcaataaaaa gttaattaac atataaattc acctccttcc
     5341 tatattggaa tttggcgttt atatgagaaa atcacccttc gcttttcaat tttattttcc
     5401 ttgctaaaaa tattataaca tataattctt acatatttta cctatatatt acttttttaa
     5461 agatttgtct atatatttct gtatacatct actctatcat cgaatagaat ttataactta
     5521 gatttgatat aataaaacca tagttattca atatatttta aacatgaata atacttataa
     5581 aggagtgtac atatatgaat atcaaatcag cttttataag aaaaagaggg gaaaaatttc
     5641 atgtatatgt ggagtacata gaagaaacaa ctggcaaaat aaagcaaaaa agttatggaa
     5701 gctatgaaaa gaaaaaggat gctgaaaaac atttaattga aataaagtct actataaaca
     5761 ataataagtt tataactcca aacaaaataa cacttgtaga gagatgttat aagtacataa
     5821 ttgcaaatga aaaaaattgg tctccttaca caactgtaaa tagaaaatct tgggttaata
     5881 attatataga accttttttt aaagatataa aacttataga tataaatcct agtttacttc
     5941 aattctttat aaataaaagt ttcaataatt ctacttcctc aagtgcaaaa gtcagatata
     6001 attttctatc ttctgtttta aaagaggctt ataggctaaa agaaatatct gaaaatcctt
     6061 gcgattttgt aaaattgcca gctcaaaatg ttacatatga aattgaaata tataatagag
     6121 aagaaacgct attgttaata gagaagttga aagatagttt gatagagata cccattctct
     6181 taatgttgct gttaggttta agaattggag aggtagctgg tcttagatgg tctgatgttg
     6241 atttagataa tagtataata aatattaacc aaattctcat atatgcaaat agtaaaataa
     6301 cttttaaaga accaaaaact gcaaaatcaa aaagaacgtt gtcagttcca aaagaattaa
     6361 ttgaaaaact aaaaatagaa aaattaaaac aaaacaaaat gaaattacaa ggtacacttg
     6421 aaaatgaaaa taatttagta tgtttaaata caaatttaaa accttggata ccaactgcat
     6481 taagtaaaac ttttcataac tttattaaaa gaaataattt aagaaatatt agagtacatg
     6541 atttaagaca tacaaacgca agtttgcttt tgctaggagg tacaaatatg aaagttgttt
     6601 cagaaagatt aggtcataca gatataaaaa taactatgaa taggtactct catgttttag
     6661 aggaaatgga caaagaagct tctgataatt taagtaaact tctatttaaa taataaaaac
     6721 tgactgtcag ttaaatgtca gttgaaccta aaaaaatagg ttttgtcagt taaatgtcag
     6781 tcagttagtt tataataatt tcttttaaat accgctaaaa ctgcacgttt taatacttat
     6841 ttatgtttgt ttatatatat ttattattcc ttattaaaat aatatcctgc tcctcttatt
     6901 gttataattt tctgaggatt tttataatct ttctctattt tctttcttaa tccattcact
     6961 gcaactacca cactatagtt atcctctaag tattcattca tccatacatg ttcatatatc
     7021 tctttagtag tcaaagtctt ttcaggattc tctataaaaa agtttaacaa cttattttct
     7081 gttggagtca attttattat tttatcttct aactttatta ctccactagt tctattatat
     7141 tcctctaatt ttgtattatt ttcattatta tttacatatg agttcattct tcttaaaata
     7201 gcttttactt ttgcgtataa tatttctaaa tttagaggct ttattaagta atcgtctcca
     7261 ccagaattta aagcatttaa aatgctttgg tcttcattta tataagtcat ataaacaatt
     7321 ggacaagtag ttacatttct aattttttta caaagagtcc atccatcacc atcacttaga
     7381 attatttcta aaaatattaa atcatattta ttgctaaata tttttccaat agcttcttca
     7441 caattatatg ctaaatctat acttattcct ttttcctcca gaaatccttt tagcttctgg
     7501 caattatcct tgtctccatc tattatcaat atcttagttt gcattataat cactcccaaa
     7561 tatcattatt cttttatatt aaataagcta ttattataaa aaacatagac ttaattttat
     7621 tgtaaaaaca gttccttttc ctagttctga atctacaaat atttctccac catgctctct
     7681 tataatggat ttgacaatat atagccctaa cccttgccct tttggctcat tattgtctct
     7741 ttctgtaaag aatctgtcaa atacctttgg tatattttct ggaggtatac cttttccatt
     7801 atcagaaatt ttaataattg caaatccatc ttctttatcc attgataaaa ttatctttcc
     7861 atcaaatgga gtaaaggtca aagcattata aattaaattc tcaaatgctc ttgtaagcat
     7921 ctctttattt atctttgcat atattttttt ctccaatacg taagtttcaa agtttacacc
     7981 acatgcttgt gtatctggca aattattttc atatatctct ttaataaaat tattcagaca
     8041 tattttttca ctaataccaa tgcttttatc ttgtgatgta aattcttgca aactacgtac
     8101 tctattttgt acttcatttg acttttgatt tatagcataa agataggttc ttgtctcttc
     8161 atctacatga atattaccaa cctttatcaa atctataaat gcttgtatag ccgaaacagg
     8221 tgcctttaaa tcatgtgcta catctgccaa gaatctttta cgttcattta acaatgttgt
     8281 aagttcatta gttctcactt caacttcatg ttcaagattc cttgtaagtt tttcattctc
     8341 ttttattatt attctattcc tgtttatcat cataacagaa aataaaataa caattacaaa
     8401 cccacaatat tctgtttgcc accctgtaaa tataggctca aatctattac tcgtaactgc
     8461 atcaaataat atgctaattc caaaaacagt gtttactgaa actaaaatat aagaacttat
     8521 atgctcagag catgtctttt tatatattga aaccagcgaa gacattaata tatatataaa
     8581 tacaatatat ttatatatgt ctattaactt cccatatatg ttgacaaagt acatatcata
     8641 tggaagaaga ataattggta tcactataga tatgatactc attgtaattc ctaatggtaa
     8701 aattaaaaat ctatacactt tattttcttc tattttggat atacttccat ttatacaaat
     8761 aatacataaa actaccataa aatatgacaa atcttcaacc gcatatgtaa agcttaccaa
     8821 aggcagtcct aacaaatgta caaagggata ggatacatga atggcaaaga aaacacacat
     8881 acatccaaaa tataagtaaa ttttactttt gtttgaaaga aaccatacgg acaatgaaaa
     8941 tatagctatt gcaaaagttg tgaagcaaat tatactataa aaaagtaatc gataaaacat
     9001 catattactt atgtcctttg tttctcctaa tgcaggcgga taatacaaac cactataata
     9061 atgtgaaaaa ttcgatacat tgattataat ttctgtattt ttctttgcaa taaaacttac
     9121 tactgaattt ttaattttgg gtctatattt ttctgttcct acatctccta atttagaaac
     9181 catttctcca tttatccata cttcacttgc ggaaaaaatc tcaggaagct ctaaacttag
     9241 tagcttatcc ttgccttcat tttttattct catacgataa gtagcattcc catatggtga
     9301 ctgattcccc tttctcatag aaaaatctgg atattgacct ataaaaacat attctggttt
     9361 tatatcttgc tctgtaaaat cattcggttt aaatatttta tgattataaa actcccagtc
     9421 atctatcaaa aagacaagtt tccctttagt gaaagtatca ttatctatag ttaaaattcc
     9481 attacttgct ctaatagact tatatgtata tttattatca tatttataca gaacatttaa
     9541 tcctgttatt gccaacagag agactatcaa tacaatgaga gttcctttta gtatattata
     9601 ctttttcatt gcatcaacca catctctttc atagtcgtat taaataaaac aagaactatt
     9661 tattaattac agtatctcac ttatggtaca aacttatatc cttttcccca tacggtttga
     9721 atgtattgat gctccctgct taaagaatta atttttttcc tcatctgtgc aatatgaacc
     9781 tgcactgtat gttgatctcc aatatcaggc attttccaaa cttggttata tatctctatc
     9841 tttgaaaata cttgttcttt gttctcagct agaaacaata atatttcaaa ttccatagta
     9901 gttaaatcta tactttctcc atcaaaagtt acttttcttg aatttacatt tattactaac
     9961 gctgaaaact ttaacacatt aggaactgat gtaatatttt tgtactgcct catacgagca
    10021 tatattctaa gttcaagttc ttttaaacta taaggttttg ttatataatc atccccccca
    10081 gctaaaaatc cccgaacttt ttcttcttca tgctcataat tagataaaaa tattataggt
    10141 atgttaacct tttcttttat atcattgcac attttatatc catctatatc tggcaatgaa
    10201 atatccaaaa ttatacagtc taaaactata ctctctacta tatccatagc atctttagca
    10261 gtctctgatg tatatacatt aaaacctata ttagaaaaat aaatttgatt tatgtttaaa
    10321 atatcaacat catcatctac aaccagtaaa ttatacatta caccactcca ttcaaaggta
    10381 ttttaattat aattccaagt tttatagtta ttacaaatta taatgtttta ttttcatata
    10441 taactggtat tattatttta taatatcttt acaaactaga ctataatact taagtatttt
    10501 tgaataattc ttgaatattg tattaaacat taagattcat tattaaatac taattaaagt
    10561 ctccgattgt tggagaatgg agcttaaagt cattttcacg tataaattta ttatttttct
    10621 agaaacttgt ctattggcta gtttgagtat tgatttatat gatttatatg gttataatat
    10681 aaaataaatt gtattatttt ggtaaatata ttgttacaaa aggtttatat tctgcatctc
    10741 aatgtttata aaaactttat tttcttatta taatactatt attctttaaa aaaaatttcc
    10801 cttttccaac aaatggctac tttaaaagcc aaaattttac ctatcaataa aaatcttaac
    10861 gactaatact cttattttca aattttgcaa catttttgtt aattttaaaa caaaaaaaga
    10921 ctatgcaata taaaaattat attcatagcc ggttgcacca ctaactccat atatctccag
    10981 atgcccaata ataagatata cttctcagtt tctaaaatat ttttattaaa aatcttttat
    11041 atattttcat aaatttcttt tttattctaa cattgtaata ttattttgtc aatatttcca
    11101 tattcttaga gataagatac taaaatacct attttatcta aagatattta tatttctaca
    11161 ttcaataata gacaataccc tgcaagttaa agcatcattt ttatgagctt atctcacagg
    11221 gtattatatg tttactttat attataactc ttgttattga ttaactttaa taaatccttt
    11281 ttctgaaaca agtgcttgtc cttcatcact taatatataa tctattaaag ctttaccttt
    11341 ttctgacaaa ccatcttctt tattaactaa tataaatggt cttgatattg gatatttatt
    11401 agctattaca tttgcatcag ttgcttcaac atcatttatt tttaaactat ttactttctc
    11461 atcaacatat ccaaatgata tatatcctat agcattttca tttccttcaa ctgtagtttt
    11521 tatatttcct gaaccatcac ttatttgtgc atctttagtt agttcttctg aatcaaaccc
    11581 tacaatttct tggaatccat ctctagttcc tgaaccttct tctcttgata ctattactat
    11641 tggtgcatca tttcctccta cttctttcca gttagtaatc tttcctgtat atataccttt
    11701 aacttggtcc attgtcagat tttttactga gtttgcagta ttagttatca atgctatacc
    11761 atctattgct attttagttt cctttaatcc agcacttttt tcttcatctt ttaaatctct
    11821 tgaactcatt cctatttcag atgttccttc tatagcattt tttatacctc cagaagaacc
    11881 aatctgttgt acttctacac taacaccttg atttttttct tgaaactttt ctccgatagt
    11941 ttccataaga ggacctattg aagttgaacc tgaaacagaa actttgcttg aatctcctga
    12001 atcacctgaa cctcctgagt tagaactaca tcctactgct aaagctccaa ctaacattgt
    12061 actagctaaa agaacgccta ttttcttttt aaacatttta cttacccccg cttatatttt
    12121 aattttttgt tgtcattttt ctatatttta ataatacaga ttctttgtta aatgaatatt
    12181 agagcagggt taagtaaatg taaatattgt taaatacatg taaaaactta attttatatg
    12241 atttattctt aattagatta actttttaaa gttactttag gcagatataa acataataca
    12301 actcatatta tcagaagtct tcattgaagc tatcaaccta tcacatccta taattctttt
    12361 tctagtttat taactaattc agcaaataca tttaaggctt cctctataga ttcttttttc
    12421 gtcatatcta caccagcaga ttttaattgt tctagtgggt attctgaccc tccacttttt
    12481 aagaagttta tatatctatc tactgcagta cttccttctg aaagtatctg ttgacttaaa
    12541 gcacttgcag cagaaaaccc tgtggcatac ttatatacat agaagtttga ataaaaatga
    12601 ggtattctcg cccattctat tcctatttgt ttatctacta ttgcagattt tccgtaatac
    12661 ttttcattta atttgtagta tatattagta aattcatcag cagtaagtgg ttctccactc
    12721 tctacccttt gatgtacaat tttttcaaat tcagcaaaca tagtttgtct atgaactgta
    12781 gttctaaatt gttctaaata ataatttaat aagtatatag tttcatcctt agacttagaa
    12841 ttttctaata aataatttat aagaagtaat tcatttaatg tagatgcaac ttctgcaacg
    12901 aatatcttat agtctgaata taaaaatggt tgacttgttc ttgaataatg actgtgaaca
    12961 gagtgcccta attcatgaac taaagtgaat agagaattaa ggtcattttt atagctcatt
    13021 aatatataag gatgtgaatc ataacttccc caagaataag ctcctccttt tttaccttca
    13081 ttatcatata catcaatcca cccttcatca aaagcacttt ttatgacctt caagtattct
    13141 tctcctaaag gtttaagtgc ctctaatatg atatcctgtg ctttatcata tggtatatcc
    13201 atgtcaaatt tatctgtcaa aggaacatac aaatcataca tgtgtatttc attcaatcct
    13261 aaaaatttct ttttaagctc aacatattta tttagattag gaatactttt atctatagct
    13321 gatataagat tattgtaaac atctaaactt acatcatctg aaaataaaga cgcttctatt
    13381 gctgaattat actttctagt ttttgcgtaa aatatctctg attttattcc accataaagc
    13441 gttgaggcaa atgtattttt atatttctca tatgttgaaa attcaccttc aaaagcgtct
    13501 tttctaactc tactattctt actttttata aataaagagt agtttgaatg agaaagctta
    13561 accttattcc cctcctcatc ttctatctca ggaaattcca tatctgcata tgctaacata
    13621 tcgtatacat tttctggaat tgtcgataat tctgatgtag ctgcaagtat ttcttcctct
    13681 cgttcactca aagtatgtgg tttatctctc aatatatcct ttatatattt tgtataaaag
    13741 gatagcttct catcttttaa gtattcactt aacttattct cttctatcgc cagtatttct
    13801 ggaactatat aagaagtagc cacacctaaa tcagtagata acatttctgt cttagtggct
    13861 cttccttgat tatcattaat tctagtatct tcatgttgtt tcatatgagt atatacatat
    13921 aaattttgaa caatcctaga tgcattttca gagatattta atactttata taagttctcc
    13981 ttactctcag aaagcttccc tttatattct tttacttctt ggataagatt ttttacttta
    14041 cttatgtctt tttcaatttc ctctttactg gagtacatct tatctatctt ccatttgtac
    14101 ttttcttcta ttgtacttct atcagttccc atatcataca cctctatttt aatttgtttt
    14161 atattttatt cactttacaa aatatattgt atatatttta gtccaaataa tctacattta
    14221 ttactccttc tatcatattt atttctttca taacatcgtg taagtgtatt ctcttagcat
    14281 aagatacaaa aaaattaacc ttccagtatt cttcattacg acattctatt tccatatttc
    14341 ttacaataag ttgatttttt tcaaatttat catataaaaa aggtatagag tccaaattgc
    14401 ttaattttaa tatcaataca ttcttttctt ggctaaataa aaacgtattg attatcctaa
    14461 gcacaaataa tgctatcatt acaaataatc cacctagaat tgccaattca taataaccat
    14521 atccaactgc tataccaata catgcagttg cccacatccc agcagctgta gtaagccctt
    14581 ttaccccacc tttatttttt aaaattgctc ctgcacctaa aaaaccaatt ccagataata
    14641 cttgagcagg cattcttgct gggtcagcat ttgtatacaa attataatca aagaataatt
    14701 gaatcgaagt tattgaaaca atacaagaac ctattgcaat tagtatatgt gtcctaaatc
    14761 ctgcaaactg tcttattttt tctctctcta agcctattat tcctcctatt attagtgcta
    14821 atagtaacct tattgctatc tccttacttc ctatatcaat cataatataa aaccctcctg
    14881 acttaattac aacttatgtc ctacagataa tttacacatc agaaatacta ttttatatct
    14941 taatattatt attaatatat gtaaaatata gccatctgtt aatttttgat acaaaaaaac
    15001 ccacaactgt gggctatttg cttaggtaca tgtatttatt tattaatata tctattttct
    15061 tacttgattc tactaactct tcttgaaata tttctggata ttctatgtat gtatttatct
    15121 cttccctaac tgcttcaatc tcatttttta acgcttctaa ttcattgttc gccataataa
    15181 tcaccactat tacaaatttg tatattttta tatacatttt atcaaacaat attatatttt
    15241 gtcaatatta tgtcaataaa acttactata aaaatgcttt aatttaggta ttgtatacct
    15301 ggatactaag cctacaaaca taccagttac taatgatgcc attaacataa atggtaagta
    15361 ccctatagca agtatatttt ctatgattaa acttgcaact attaattgac ctatattatg
    15421 ccctattgca cctataatgc ttatccctat tagtgataaa tcttttattt tactcgctaa
    15481 atacataaat aaaagactca gataagctcc tcctatacta aatagtagat atgataaagg
    15541 gcctgcaaat attgatgaca aaattaccct gatagtaaca attataacag tatctttgac
    15601 acctaacaac attaatgaaa ttaaagttat aatattgctc aaacccaatt ttgcccctgg
    15661 aaatataact ataagaggat ttggtatata tgtctctaat acatataaag ctaaactata
    15721 ccctatcata agacctaaaa atgtcatttt tctagttttc attaagttaa ctcctccaaa
    15781 ttttatctat catcttacat tataatacaa aatatataaa aacacctaat ttagactaaa
    15841 atatttttaa tctatttaga ataaatatta gttatttcaa tgtgcaatta cctctataaa
    15901 tcttgacttt ttgtatcata cttgttacaa ttttaatgat aatgaatttc attaggaggt
    15961 gttaataatg actgtttacg atttaaaaat aggagaaaaa ggatttatta atagtataga
    16021 tggagatatt aaattatcta aaagattgct tgcacttgga tgtataaata gtactgaaat
    16081 agaagttaaa aaggttgccc cacttggaga cccaattata attagattta gaggctttga
    16141 ccttgcgatt agaaaatctg atgctaaaaa tatttcttta caataataga ggaggagcta
    16201 cccgtgatta atgtagcatt attaggaaac ccaaatgtcg gtaaaactac tgtttttaat
    16261 ctacttacag gttcaaatca atatgtaggt aactggcctg gtgttactat agaaaaaaaa
    16321 gaaggatttc ttggaaaaga gataaaggtt gtcgatttac ctggtatata tgcaatggat
    16381 actttctcaa atgaagaaaa ggtttctaaa tcatatttag aaaatgaaga tgttgatgta
    16441 atagtaaatg tagttgatgc ttctaattta tcaagaaacc tttacttaac aactcaactt
    16501 atgcaattta acaagcctat agttatattg cttaatatgt tagacattgc agaatctaaa
    16561 ggagttaata tagatgccaa aaaattaagt gaagaacttg gagtaattgt tgttccaatt
    16621 atagcaaaaa agaaaaatgg tgttgatagg atagaagaag agattaaggg agctacgcaa
    16681 aaagctttta tatatcagaa aaactttgga agtgaaacag aaacatataa aaaattagaa
    16741 tccattttat cgagatgtac aaaaactaca tatacacaaa agaaatctat cagtgataag
    16801 atagacaata tagtcttgaa tcctatatta gcatatccga tatttattgg tgtattgttc
    16861 ctcttattta aatttacctt tgactgggtc ggaggaccac tacaagaggg atttgctagt
    16921 cttatagagg cttatatttc tgcacctgtt agtgatatgt tatctaactc tagcccatgg
    16981 tttaaatcac ttatagttga tggaataatt ggaggtgttg gtggtacttt accattcttc
    17041 cctttaatat ttacattatt ctttggtata tcgttgtttg aagatagtgg atacatgtca
    17101 agaacagcat ttttaatgga taaagttatg agaaaggttg gtctatctgg taaagctttt
    17161 atacctatag ttatgggtat gggatgttct tctccagcta taatggcaac tagaacattg
    17221 gaaagcgaaa aagatagaag agttacagct cttattgcac cacttatgac ttgtggagca
    17281 aagctaccta tatatgcact atttgtagct atattctttc cacataatgc tgctttagta
    17341 actacgtcac tgtatttggt gggtatagtt atggcaattg tagttgcatt attcttaaat
    17401 aaaacagcct ttaaaacaga ggctgaacca tttatattag aattaccaga gtatagaatc
    17461 cctactatag atgcacttat taaaaatact tggaataaat caaaaggttt cttgataaga
    17521 gttgttactg tcatgtttgc aatgtcagtc gtaatttggg gactttcttc attcaatgtt
    17581 tttggatata cagaagatat aaatgtaagc ttcttggcta ctctaggtca tattatatct
    17641 cctatattca aacctcttgg ttttgatgat tggagaactt cagttgctat tttaagtggt
    17701 cttggagcaa aagaaatcgt agtaaactct ttaaatatac tatatggtaa tctaactgtt
    17761 gtcttaccaa caatatttaa tggagttact gcatatacat tcttgatatt tactgcttta
    17821 tatactccat gtatagctgc acttgcaact atgaaaaaag aatatggcaa taaaatgatg
    17881 tttacatcat ttgcatatca atttatacta gcatggataa tggcttttat agttaaaagt
    17941 ataggtggag tactatttat gggtaattca ataatggaag ctttgatagg tggaataatt
    18001 atagtccttg cactctttat tctgtttaat aaattcaagt ctacaaaaaa cggaaatgtc
    18061 tgtagtggat gttctatttg ttctggatgt ccaagtgcta attcttgctc aagtaaggaa
    18121 gacagcaata aaaaaaataa tgcacactaa tatataaata ttttagttta aaataagata
    18181 aaagtgggtg tctcaaaatt aactttttag ttcatgaggc actctttttt atagaaaatc
    18241 aaatatattt tcatcatttc aacagtaaaa aagaggctta tctctatttt gagacaacct
    18301 ctttttttgt tacttattca gtttcttgct acctaacttc atgtggaacc tagtatcttt
    18361 tggaacactt gggtctacac ctcttaatgt aggtatttcc ccacatatta gttgtatagg
    18421 tactataaaa ttaaatgttt gatagtaagg attatctgtg atatcaatct ttaaattttt
    18481 atcattttct gtaacatctc tacctatagc aaatacattt tccgtccaac cagaaagtac
    18541 atcaatcatc ttagttactc taggttcttt tcctgtatct agtataaata tagtagaatc
    18601 actatttata gcattatata taccatgtat aaactcttca aactcatacc cagttacagg
    18661 tattctcatt gtttccaata attttaatgc tgcttctaat gtatctccat atatatcaga
    18721 gtgacctatt attcttattt ctttagaatt aactaacttt tctttgtttc tttcaatcca
    18781 ttgtttagag agcttataca ctgcttcaaa tctattaatt gcatctaata tcttatttat
    18841 ttcctcattg tacttttcac tagatattat acctttttct ctagctattt gaagacctaa
    18901 taacattaag tttaactttg tacaataata tccctttgtt ttagctccag atttttcctc
    18961 accacaattt actgttaata tataatcaga aatctcatct attaaagcat tcttacaacc
    19021 tgccatagat gctattttac agcccttatc ttcagctaac ttcatagcgt tgtatgtaga
    19081 ataactactc ccaccttgag atacacctac tactagggta ttttcattat caaacttgaa
    19141 tgtatcttca gttatcataa atggatacat tttcacaaca tctatatcta ataaattttg
    19201 taaatatggt tgcacttgca ctcctgagtg atagctagta cctgaacctg ttattataat
    19261 cttttttaga tttgttctct taacttcatt aaataagcta tctgcattag atataatttc
    19321 tctcattcta actggtgttt ctaacatata atcttgtatt gtcattttat acaccttcct
    19381 tatctatata ttcaataaat tataattaat ttctataaca aacctatagc atgtaaagcg
    19441 attcctgtta ctatagtgcc tatagttaat tttgttacac ttacctttct ttttaacatg
    19501 tagtatatta caaatacaaa ggttaaaggt aacatattag gtattatttt atctagtata
    19561 tcttgtaaaa ttacttctgc accatttaag ttgaatttca gaggagtagt tatactcaac
    19621 atagttgcaa ccattcctcc tacaacgaat aaaccaacag ttgtagccat agacattatt
    19681 ttctccataa gtccctctct ttgtattctt tcaagagaat ttacccctac ttgataacca
    19741 tacttaagtc caaatattct aagggcaaat gctggtatat tgtataatag taagaataat
    19801 agtggtccaa agatattacc ttcttttgca agtgatactc ctactcctgc tgctataatc
    19861 ctaaatgttc cccagaataa tgaatcacca attcctgcaa gaggtcccat aagagctgtt
    19921 ttaacagcac taattgaact ttcatcaaat tctggattat tagcattctc ttcttccata
    19981 gctgctgtta tacctaatat agcaggaact accactgtcg ttgtattaaa aatctccaaa
    20041 tgcctttcta ttgcttttgc ttgattttct ttcttattgt atagcttctt tattgcaggt
    20101 aacattgaat aacagtaacc taagttttgc attctttcgt aattaaatgc accttgaaga
    20161 gcaaatgaac gccaaaacat acttcttaat tctttttttg ttaatttatt caaagtcaat
    20221 ctctccttcc gttaaagtat tgattgctaa ttgaggattt tgattatttt ctttgttatt
    20281 gatataaaag tttagtacaa atgctacaca tactccaaat aaagctatag cagttatatc
    20341 taatccacca taagatgcta acaaaaaccc tataaagaaa aatacagaca tcttttttga
    20401 aagtaacata tccataagca atgcaaaacc tactgctggc aacaatgttc ctgcaacacc
    20461 cagtccgtct aatataactt taggtattgc atttatcaat gctgtaactt tatcagcacc
    20521 aatcataatt gctaaaaagg ttggaactga tgtacttaaa aagaataata ttactggcaa
    20581 ccacatcatt atggtaactt tcttaaaatc agcttgttta gcatagaaaa ctgccttttg
    20641 agaaaagtac gaatttatta ttctaactaa tactccaaga gattgtgcta agactgctac
    20701 tggtactgct actgctaaag caacttctgc accattacct gataatatag caaaagctgt
    20761 acctaatacg cctcctgtta ctacatctgg aggagtagct gcacctattc ctgcaattcc
    20821 catccaaatt aattcaagct gtgcaccaat cataattcct gattttatgt ctcctaaaac
    20881 taatcctact aacatacctg taactattgg cctatcaagc atagattgac caaatatacg
    20941 cccatctagt ataccaactc ctgctataat agctaacata gtagcttgta ctaacatatt
    21001 gaacctccat tttaacttag tttaatttac attaaattac attacatttt tgattttgtt
    21061 ttgattttct aataactcat ttacataaac aattccattt tttgcttcct ctaatcctga
    21121 tttaactatt agttttgtat cctcctcaac taataaaagt atagataaaa gcattggtaa
    21181 atttactcct gtcaataatt caaatttgaa cccttgtaaa agtaagtttg tacatatgtt
    21241 tgccacactt ccaccaaaaa catctgttaa gacaacaaat tcttcactat ctttattatt
    21301 tgataatata cttctaattt ctttctcagc atcatctgtt gatttatctg ttgtcataca
    21361 aaaatactca atattagtta atgaaccaat tattaattta cttgtgtcaa caagctctct
    21421 ggacaattct ccatgtgttg caattagaaa ttttttcatt ctctttctcc taaattattt
    21481 tattaaattt gatagttgtt tctttttgtc tctaggtaac attctaaatt ctatatcaat
    21541 ccctaaatca cctatttgtt taaagttatt tatatcatca tcatcaacag caactaaatc
    21601 tgtaagtttc ttcttccctt cttcatatct taatcctcct acatttattt cttttaatac
    21661 tcctcctgaa tttttagcta caactaaagc atctttggta ttttttacta acactaatac
    21721 attgcttttc tttgaagaag caaatttttc tactatttct ccagattcct ctacccccct
    21781 tatatataaa gttacattgc taggtttcgc taagttcagt gacatagctt tcatttggtc
    21841 attttttgct tcatcatttg caactagtat tacatttata cctagtgatg ttgcccatcc
    21901 atatgcaacc tgaccatgta tcaatctgtc atcaattctc atcaaagata ccattttccc
    21961 caaatcctcc atcatatatt aaaattttta ttgtttatac tctcatttat ctataaaagc
    22021 aaaaagtatg ccaaatactg gcatactttt ttaaatttca ttcacttatt ttgtaatctt
    22081 gtattttact gtggtagacc atagataata ttataaatat atcctatctc tgaaattggt
    22141 atttgcacac tataactctt ttctagcaca ctaaatgcat tttttattag ttttacttca
    22201 ctatgatggt ttttgattaa caaatccata tcagtatact cttcaatttc agtttgtcta
    22261 actaatcttt caatcataca acttaagtga acatataaag aaatcttttt atcatttgaa
    22321 agttttttct tttgaatatt ttctatagca ttaattcctt cttctattct ctctattatc
    22381 ttttttgaat ctaaaatagt tagactatct attactctaa ttaatgaaaa attctttaca
    22441 atagaatcat ttatgttctt tattttttca ttttctacta ctctgctaaa tattctaaaa
    22501 acatcatctt ctccttttcc tgatattata tcctctaata atataaaatc taccccattc
    22561 acatttggat tggcagttcc tactatagcc atcacatcat acatttcaaa aactggttct
    22621 ttatctccca tagagacaag actatcataa tcataaggta ttattttgac atcaactatt
    22681 ccaattaaac tttcggaaag tagatgttgg atttttatag cagtacctat ccctgtaaaa
    22741 caagatgata ttatagcata ttctttattt ttttgaggat aatacaattg tatattaggt
    22801 ttagtttctt catccataat ttctgcaatc tcttcaatgt ttttaccttg cattaataaa
    22861 tttcctactt ctagtgcaga aatagtggat atttggtcta taaataacat tgggctattt
    22921 atcttattct ttaaatcttc atatataaga ttaagagagc ccatatcaaa taacacaatt
    22981 aaaccattct ttatcctatc tccttctagg tatctagaca tttgttttga tacatcagca
    23041 atagtagcat ctataggcat atcaatagct gtaaatatat ttttacccaa catccgatta
    23101 catacattcg ccatactact ggcagtagca tatccatgtg ctataatagt cgcattaact
    23161 tgattaaatt tcattcttat aattgttgat ttaataaata taatcattat gattgtatct
    23221 acattattaa gatacatatc caatctattc gttattaatg ttgatatttt acttattata
    23281 gagtattctt tgtaactctc tttttttaaa tatattagta atttattttc taaagcttta
    23341 tactcatcag acaattgata agattcgtcc ttcaaataaa gataagacga aaatgccaat
    23401 acattattcc catcgtattt tatattgtta ttaacttcta aatttctaaa tatatcctgc
    23461 attatcgata ttataagctc cataagtacg ttattatttt catcattatt tgaaaagact
    23521 aaattgtcca ttagtctaat cattagatta gaactctttt tactaaattt ttcctttgtt
    23581 atttcatttt tttctagtct atcaaagtaa tctaaacatt ttatgaaact ttgatagatt
    23641 atatttcttt tatttcttcc atttgacatt tcaatactaa attgtttagg agaaaagata
    23701 atgcttttgc ttttaccact ttggaattga aatacatcta cattttctat ataaagattt
    23761 ctaggaaggt cttgaagagt aacaaaaata tttccatttc ttctttgatt ttttgcataa
    23821 gctcgtccac atgcatattt tattacattt ttacattcac ctatattccc cttgaatttt
    23881 atctttaaaa tcgcatttaa tgtaatttga gttatctcta taggcaaacc aagtacctta
    23941 ctttcttcat aaataaaatg ttctacaatc ttcctttttt caatagtccc tctttcttct
    24001 atattgggaa cataaatatt tatgggtatt cttcttaaaa aagtttgtaa aaattcagat
    24061 agactttctg ttgtagcaaa tattaatctt accctagctt ttctaattac tccattctct
    24121 ccaatcctag aaaacgtacc tgtatccata aatgtaaata acttttcctg accttcacta
    24181 tttaatctat gtacttcatc taaaaataaa acaccaccat ctgattgttc tattagacct
    24241 gctctagatt catttgctcc agtatatgct ccttttacat gcccaaataa tagactagac
    24301 aataactcca aattattata atactgcgca cagtttaaca cattgtatgg agaatttttt
    24361 tctaatacat tactgcttac actatatttg tatattatct tggctaaaaa agtttttcct
    24421 actccacttt cacctgtcag cattattgta agtccgccat ttggataaag tacagcggtt
    24481 tttatttgtt cgattacttc ttttaagcta ttatcatatc ctatgatact attaaacaca
    24541 gtctcttgct ttaataattt acactcattt ttaagttcat ctaaattttc ataaatactt
    24601 ttttttgtag gtcctactac atcatttatt ttatttttag gtaaaaaaat aacaggtcta
    24661 ctgtttatct ttataagatt atcagatttt actaaatcat ttaataatct acttgattga
    24721 gttctactta aattaaactt ttttactata tcttctgtta ttatgccact ttctttttta
    24781 agttcatcaa agttgttaaa taatacacat tcatttacaa aacttaaaat ttcatccctc
    24841 atgttcaacc tccaatacaa atatcaataa tactataata ttagtatatc atttatatat
    24901 ttatgaaaaa gataattata ttcctatctt gattctcttt tgtaagattg taaaatcaaa
    24961 ctttttataa gtataaaatc tagatttttt aacataatct caaggttctt atctttccat
    25021 atatctgaca tagaatttat ataagaatat atttattgta tttattataa taaaaagtaa
    25081 aacattatag gtattttaaa acttattagc gaagaaaata tttgtaactt ttattacctt
    25141 atgaatatta tttcaaattt aaaaaggcta taaataaatt tatttttaaa taaatctact
    25201 tataacctca caataatact tataaatttt attttttcac aatgatatat ctcaaatata
    25261 gtt
//
LOCUS       DAEORM030000055        25076 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.055, whole genome shotgun sequence.
ACCESSION   DAEORM030000055 DAEORM030000000
VERSION     DAEORM030000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 25076)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25076)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 25076)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25076
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.055"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            complement(120..728)
                     /locus_tag="KRH23_002929"
     CDS             complement(120..728)
                     /locus_tag="KRH23_002929"
                     /EC_number="3.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003905 - alkylbase DNA N-glycosylase
                     activity [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="HHS5226206.1"
                     /translation="MEKDFFRKNGIDLAKSILGKYLIRKYENKVIVTKIIETEAYMGV
                     NDKGAHVYGNKKTDRTKPLYLDGGHIYVYLIYGMYNCLNLSANIENVPECVLIRGVEP
                     ITSLDEISMNRYNKAYTELSKYQVKNITNGPGKLCKALKIDRSLNSKSIMGEELYISD
                     FYYDDKGKKVFSKDELDIKTSKRINIDYAEEAKDFLWRFYIE"
     gene            complement(837..3575)
                     /locus_tag="KRH23_002930"
     CDS             complement(837..3575)
                     /locus_tag="KRH23_002930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HHS5226207.1"
                     /translation="MESKGTLSKNKVYILANGLFLVIALLNINLYTVSINMYRIILLW
                     IFGYSIVYISSFKTDEFINILKVGCLVLVFVSILGVVNLKIQKFQIVLLNLSIINMST
                     FIYLTISKVKKLRISPILIFYSAFVILDYFIRNIFSDINWNMIIILINICISMFNLLY
                     LLNKLDSNIEHYKLIKDLTYFVFFTTIICFVAISKINIVDSDRLIGVIYLLLCNHTYY
                     VYVYSLNNRVVYPYYELDSINKKLSKKSEQLGKINLAIEKDMIIQRTLKNYIDQRKEL
                     LRQALDTIPNVWIVTDYDFNISYTNNKFKDEFSKDMNNYYKILTFIKEDEKVAEKLKK
                     FDNDISIIDKLVELNDKIYLLSLSNNKDESNYLISLNDITNEIKIDEEIRNINKDYEN
                     IILNIPSPILVRSAEGGIKKNKVISINKKYEKSFKCVSSDLVDMTLEQYFETFNIDFF
                     DNREFKRLNLTQEKKAEIVSYNDTANCIVNFVMSDSEGEEHVEEVRVGDYWSDNKLFK
                     LLTFRDITKEINILRTVNEQKIIYEKLLDVIPEAIFLEDLSTSRVLYTNRAFRELFGI
                     SSDVLGVTTQKYRNILVKKYINNLNIGEREKSIHIVNENNHIKEVKMISRTLYFGQKR
                     SRVRIIKDLSVQRESERLKKALIKQRQYDQMKMEFYANISHELKTPLNNIYSSVQLIE
                     NLYKKGKIIDFQDILKEHIKITKQNMFRLLRLIDNIINISQVKSDIYKIKAVNFDIID
                     ITERIVTSISSYAKSKGIDLIFDTDEETVMVGLDPESIERIILNILSNAIKFTLEGGE
                     ILVGIYKKDETVEIIIKDTGVGIDKEKLNDIFNRFKQIENSGISNEFGSGIGLCLTKS
                     LIEIQNGKIYIDSKVGEGTNVKVIFPIKEVVEEVYDNSNYNDNIEKFEIEFFDIYK"
     gene            complement(3723..4514)
                     /locus_tag="KRH23_002931"
     CDS             complement(3723..4514)
                     /locus_tag="KRH23_002931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HHS5226208.1"
                     /translation="MKLKKLLSVALVSAIAISAVGCSNKEDKKILVGASSNPHAKILE
                     VAKPLLKEKGYDLEVKIFDDYVLPNTALDEGSLDANFFQHIPFLEETVKEKGYKLTYT
                     SKVHIEPMGFYSEKVKSLDELKDGAVIAVPNDATNGARALKLLAKNKLIEVKDGELIT
                     KKDITKNPKNIVIKEMNAEQLPTVLKDVDGAVINSNYALTANLNPTKDAIVIESSDSP
                     YVNIIACRENNKDSDKIKALSEAMNSKEVKKFIQDEYKGSIVPAF"
     gene            complement(4550..5206)
                     /locus_tag="KRH23_002932"
     CDS             complement(4550..5206)
                     /locus_tag="KRH23_002932"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter permease"
                     /protein_id="HHS5226209.1"
                     /translation="MNSLIDFLTTLFPNALLQTLYMVIVPTIVATILGFILAIILVVT
                     KPDGLKPNSTINSALGFIVNIFRSFPFMILIVAMIPITRLIVGTSIGETAAIVPITIG
                     AAPFIARIIESSLNEVDKGLIEAAKSFGATKRQIVFKVMIKEAMPSIVSGITLSIISI
                     LGYTAMAGAVGAGGLGNIALIYGYQRFDTAVMVYTVIALIILVQIIQGVGNLAYKKLK
                     "
     gene            complement(5199..6164)
                     /locus_tag="KRH23_002933"
     CDS             complement(5199..6164)
                     /locus_tag="KRH23_002933"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HHS5226210.1"
                     /translation="MISIKNVNKYYGKIQVLKDVSIEIESGEIFGIIGHSGAGKSTLL
                     RCINGLEEYQEGSVLVSDKEVKSLNEKQMRDLRKELGMIFQHFSLLERKTVFDNVALP
                     LECFGYSKAEIKKRVLELLEVVGISEKKNDKPRNLSGGQKQRVAIARALALNPQVLLC
                     DEATSALDPNTTKSILSLLEDINKKLGITIIVVTHQMEVIKQICGRVAIMENGEVLEV
                     GDTEEIFLRNTKGLRKLIGEESIILPKGTNIKILFPKDISNEAIITTMARELNIDVSI
                     IFGKLEQFKDDILGSLIINISDKSGEQVKQYLTSKGIRWEEMINE"
     regulatory      complement(6270..6376)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            complement(6666..7610)
                     /locus_tag="KRH23_002934"
     CDS             complement(6666..7610)
                     /locus_tag="KRH23_002934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HHS5226211.1"
                     /translation="MSRAERLIELMITINAKRSFTAGELAEEFSVSKRTILRDLQVLE
                     SIGFPLYSKVGAAGGYHVLKERILPPIAFSESEVKSIFFAYQSLEYYNDLPFEQETIS
                     VLKKFLNCIPNDIQYNIENIRRKFVFWTPDRHCSTPLLKELFNIVMNEFTIKIEYSSK
                     QKNSVRTIVPIGLYAMNGLWYCPAYCIKSESIKEFRVDRIVKILSIENLSSKKYKVLS
                     SIHDYLKNMEVGTDYHIKINLTDEGVKRCETEFLLARGLKILSKGGYIDMYIPKSTLN
                     WVAEYFLTFGKNATIIEPIELKHLIKSKVLELYNHHCI"
     gene            7793..8188
                     /locus_tag="KRH23_002935"
     CDS             7793..8188
                     /locus_tag="KRH23_002935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6194 family protein"
                     /protein_id="HHS5226212.1"
                     /translation="MNSWGERAIYYNPNGILKRGVYVLTIKEKDSNHDKGSLVSRPNV
                     YRVNIGLKKETFIEMFGYIPKRPGVGQIVDMDFDFTKLDTIMPHPIYSWMGWICILSP
                     TEKTFENFKTLIGESYNFAKQKFKKRKNK"
     gene            complement(8358..8957)
                     /locus_tag="KRH23_002936"
     CDS             complement(8358..8957)
                     /locus_tag="KRH23_002936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226213.1"
                     /translation="MKLKRTLFVGLALVLAIGITACTKNNEKPSENTGKNPNESVNNN
                     EGYMNYYSTSYNDYIAGLNRYSIYDTPESINNQFKDKEYPGNEKYLSDVKAAYKDSRD
                     KIQSFVTSLKKDGKTEDTELKKMNDDLIAEGERLVKDIDKRIEKLDKVSDEDMKKGQN
                     DFIKLVHGTEDVGNDIGSGFRKMIKDMNDRLGITGNNKK"
     gene            9203..9799
                     /locus_tag="KRH23_002937"
     CDS             9203..9799
                     /locus_tag="KRH23_002937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3793 family protein"
                     /protein_id="HHS5226214.1"
                     /translation="MSCCNSQFCCKNKIESSYIKWLLEVLGPVFLGSKPAEIINISFT
                     DVNREEKINDIYKYLYKCKKIDFIVIDKEKKGLKILFVNKKALSEKLKCKKTVNFLKF
                     LGYKQNTNVNAYLEHLVDKLKSDVFPDEIGIFLGYPLKDVIGFMGYSNYEVSMIKYWK
                     VYGDTKQSEDTYSKFLLHRKKMRKLLDYISVDKIVSCF"
     gene            complement(9897..10856)
                     /locus_tag="KRH23_002938"
     CDS             complement(9897..10856)
                     /locus_tag="KRH23_002938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NrtA/SsuA/CpmA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HHS5226215.1"
                     /translation="MTSLIMVLVGTVGCSTTNDKKDEPAKKEASLPKEINLTYVKSPL
                     NVPSILEKKDDLFGKEFKKDNIKVNFHELTTGPEQTQALAAGELDFLHALGGTSAIIA
                     ASNGVGLKITNIYSRSPKGYMLITNNDNIKSIKDLKGKKIVGPKGTILHQLLIAALAK
                     EGYTIDDVEYVNMDIPSAASALESKSADVAMLAGPVALKTINSGAKMIVNGEGLVSGI
                     IVTAVSDDFAEKYPELVKRFMKVHEETLKYMNENKDEVMDVVSKEVGLSLDETKEMYS
                     WYDFSSKITDKDIKELEDTQEFLMSNGMQQKKINIKDMLYNQN"
     gene            complement(10890..11621)
                     /locus_tag="KRH23_002939"
     CDS             complement(10890..11621)
                     /locus_tag="KRH23_002939"
                     /EC_number="7.6.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHS5226216.1"
                     /translation="MVRSGFLLENIYKKYLVDNKEHLVLDNISLNISSEEITVILGES
                     GCGKTTLLRILAGLEKATSGNIYFFNNDKKCTPKVGMVFQESRLMPWLNVSENILLHT
                     EKDNRNKVDLDKYLKMMKLEKFKNSYPNELSGGMAHRVSIARALSFNPDILLMDEPFA
                     ALDYFTRRKMQKEVVNIHKNTKKGVVFVTHNIEEAMEIAKKIIVFSKNKRIKQFSVED
                     EYNRDLTKNYYINLKKEILRELGEF"
     gene            complement(11614..12384)
                     /locus_tag="KRH23_002940"
     CDS             complement(11614..12384)
                     /locus_tag="KRH23_002940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHS5226217.1"
                     /translation="MFEKIHKRLKGYYIFLIILILWKIVCVLGIWSSYILPPPEIVLD
                     TFIKMIYDGSIFLNVYASVRRILIGFLISSLMAIPLGVLFGVNKKMYEYFKPLFEFMR
                     STPPLALVPMLILWFGIGEESKIIIIILASFFPIFLNTLKGIKNCDNKLIEVGKSFNL
                     SKKRIFYKIIIPNSMLDIVVGLSLGLGYSFRAIIGAELIAASSGLGYLISDGKDMSRT
                     DVVLVGIFVIGFLGILSDYLFSKIITKFSKGKQVDLNG"
     gene            complement(12469..13179)
                     /locus_tag="KRH23_002941"
     CDS             complement(12469..13179)
                     /locus_tag="KRH23_002941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AIM24 family protein"
                     /protein_id="HHS5226218.1"
                     /translation="MFKFDVTNELMCIARGSGKFFAKKGAMVAFKGNFNFEKLLLGPS
                     NGGGLGRALLGHVQRSLTGEQMPIMVVEGEGEIYLAQNAYHVDVISIDPGDSIYVESE
                     NLLAFSEQLNYSVKLIGSGVISQKGLFTTHLVNKTGQNQDVAIITDGNPLILEGPCCV
                     DPDALVAWTGREPYPKVSKLSWKTFIGQTSGESYHMEFVEPGQIVIIQPSERLSGLKT
                     DSTPSDRMSSGGLRLGID"
     gene            complement(13359..13511)
                     /locus_tag="KRH23_002942"
     CDS             complement(13359..13511)
                     /locus_tag="KRH23_002942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="HHS5226219.1"
                     /translation="MATFIIAAIVVVLMALAVMYMVKNSKKNGSSCGCGCSGCSSSKS
                     CHSAKR"
     gene            complement(13537..15693)
                     /gene="feoB"
                     /locus_tag="KRH23_002943"
     CDS             complement(13537..15693)
                     /gene="feoB"
                     /locus_tag="KRH23_002943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0015093 - ferrous iron transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HHS5226220.1"
                     /translation="MSIKIGLIGNPNCGKTTMFNGLTGSSQYVGNWPGVTVEKKGGKL
                     KGNKDVEIVDLPGIYSLSPYTLEEVVTRNFMLDDKPDAVINIVDASNIERNLYLTTQV
                     LELGIPTVIALNMMDIVNKNGDKINIKELSEVIGCPVVEVTAVKGQGIMEAAEKAVEL
                     ASSNNKLNFKLPFVDESKDAIEKIEKIIEEKTPYIDVETRWLAIKLFERDENVIQKLD
                     ISKTILNSIEEITRNCEDELDDDSESIITANRYEFISSIISSIIKKNRKGKETVSDKI
                     DKIVTNRILALPIFALIMWGVYYIAVSSLGTIATDWTNDVLFGEIIQGNVSNFLASLN
                     VAEWLQGLVVDGLIGGVGAVLGFVPQIMLLFLLLSILEDCGYMSRVAFIMDRIFRKFG
                     LSGKSFIPMLISSGCGVPGVMSTRTIENDRDRKMTIMLTTFIPCGAKIPIIALFAGAL
                     FGGASWVAPSMYFLGIAMIIICGIILKKTSLFAGEPSPFVMELPQYHIPSAKGVLIHM
                     WDRGKAFIIKAGTIIFVACGVIWFLQSFNWSLQMVDAGDSILASLGNIVAPIFAPLGF
                     GNWQSSVATVTGLVAKENVVGTFGVLFGISDATEQDPTLLASVASMFTVASAFAFMAF
                     NMLCAPCFAAIGAIKREMGSWKWTWITLGFQTLTAYIIALLINQVGSLVLGTGGSIAG
                     AIISIFIAVAVVFVVLTYSNKNMKKEKMGKLSYMKN"
     gene            complement(15793..16014)
                     /locus_tag="KRH23_002944"
     CDS             complement(15793..16014)
                     /locus_tag="KRH23_002944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046914 - transition metal ion binding
                     [Evidence IEA];
                     GO_process: GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FeoA family protein"
                     /protein_id="HHS5226221.1"
                     /translation="MNRLKDIKCGETVKVKKLEGEGATRRRIMDMGITRGVNIFIRKV
                     APLGDPIEVTVRDYELSIRKSDAEKIIVE"
     gene            complement(16027..16239)
                     /locus_tag="KRH23_002945"
     CDS             complement(16027..16239)
                     /locus_tag="KRH23_002945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046914 - transition metal ion binding
                     [Evidence IEA];
                     GO_process: GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FeoA family protein"
                     /protein_id="HHS5226222.1"
                     /translation="MMPLILSNTGEEVVIKKISGSDKTRTFLNSIGFVVGTNVKIVSK
                     IDGNLIIDVKDTRVALDKKMASRIII"
     gene            complement(16560..19457)
                     /locus_tag="KRH23_002946"
     CDS             complement(16560..19457)
                     /locus_tag="KRH23_002946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HHS5226223.1"
                     /translation="MKAFKKHFLILSLIFLLIISCFNNILCFADESENSKKIRVGYCD
                     DYGIISSSKEHSYTGYGYDYLREISKYTRWEYEFVKGSWEECLDRLEKGEIDLLGPLQ
                     KNDERNKLFNFPKLSSGYEYSALYTKDSNNNMFYEDISSFKGMRVAVLRGNFHNTAFE
                     KYREENNFSVEYIYCNSIDELIESVNEKKADAFVCGSIINAKGMKIVSKFSVEPFYFA
                     TAKDKPNLVKELDYALKELKINDMYYELELYKKYFKREVNNSIAFTRQEMNFIKANPK
                     LTMVYDSEWSPVEYYDKESNSFKGISSDLMSIISKKCGIKFEYIKTKNYNESLDYIKS
                     GKATMLCGSINENDKAKRFNMKLTNPYINIPMIMVGKLDTNLNNDLNIALTSSYKSID
                     SYIEKSFENAKTTSYKSVESCLNAINEGKANLMILSSYQFDELLREGKSENLSVISVL
                     DTSYGMRIGVSNKTDPILVSILNKSIDKITEEELSDCIYSNTIDKPYKVPFGVIFKEY
                     SIQIISFVCILFLIAIKYIIYNKKKKEDYLRKIAYTDPLTGADSIDKFKINSNKLFAK
                     NNPEEYALFYIDVDKFKYINDMFGYDMGNDTLIHISNTIASELKEDEIFARVSADHFV
                     LLIKYKTDDDIKTRLNNIYNKVQILSNPKINYYKLILDCGIYKISKSDNDINTIMDRA
                     NTARKTIKGGHKNSFAFYDKEMHKKILKEKEIENSMVDALNNGEFIVYFQPKYSLSDY
                     QIIGAEALVRWDNPQKGLIPPIEFIPVFERNGFIVNIDFYVFEEVCKKIREWMDEGQK
                     VVPISVNLSRMHFVNSNFIEKFKLIVDKYKIPTRLIELELTETAVLDNIEGLLDTMNN
                     LKEKGFVISMDDFGTGYSSLNLLKELPVDILKLDRAFFTEKDESNNEKIVISNVIKMA
                     KELKMKVISEGVETISQVEFLKQIGCDMVQGYLFSKPMPVKEFEKIAFKKE"
     gene            complement(19784..20392)
                     /locus_tag="KRH23_002947"
     CDS             complement(19784..20392)
                     /locus_tag="KRH23_002947"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dienelactone hydrolase family protein"
                     /protein_id="HHS5226224.1"
                     /translation="MVDNLIKYIHKSDVAIVVLHEIYGINSFIEDVCQKYYKYGYDVF
                     CPELLGEKRVFPYSKVQEAYDFFINNVGFDIYKKVEKLINDLKSEYKYVFVAGYSVGA
                     TIAWRCSEDSFCDGIICCYGSRIRDYMDVIPKCPTLLVFAKHDSFDVDSISYQLSRKQ
                     NIQIEILDANHGFIDRYSNNYSDIQTKVFTIKEKSFLSKYLA"
     gene            complement(20652..21197)
                     /locus_tag="KRH23_002948"
     CDS             complement(20652..21197)
                     /locus_tag="KRH23_002948"
                     /EC_number="1.11.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH peroxidase"
                     /protein_id="HHS5226225.1"
                     /translation="MKKFVCTVCGYIHEGDAAPAQCPVCKVGADKFEEMKGEKNWADE
                     HRIGVAQGVDEEIIEGLRANFVGECTEVGMYLAMSRQADREGYPEVGEAYKRIALEEA
                     EHAAKFAELLGEVVVADTKENLRVRVDAEYGATDGKLKLAKKAKELGLDAIHDTVHEM
                     CKDEARHGKAFLGLLNRYFGK"
     gene            complement(21315..23138)
                     /locus_tag="KRH23_002949"
     CDS             complement(21315..23138)
                     /locus_tag="KRH23_002949"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHS5226226.1"
                     /translation="MNLSTGNQKVSRLKKKEKPKDFKKTFKRIFMYFKKDKKITRFIF
                     LLVIIDSIISTVIPYTIGKVVDIIDIDTYSKSIFLKGIIILLSFYIIEFSVKLSKGIC
                     TARLSQSIVREMRSNLFLKFKNLPITFFDKSSTGDIMSRVTNDVDNISTGISNSLVQL
                     ITGILNILMTFIMMFVLSPILTFCSIILIPIVMFVSNFIAKRTRVFFKQQQVELGKLN
                     AHIEEMISNINVVKSFNYERKSVNDFKEVNDRLLNISLKSQIYTSLLMPIMNVISNIG
                     FATICIIGGVLASKDIITIGVIASFLSYVRQFTRPLNELANLFNTLLSAIVGCERVFE
                     IIDEQEEQEVHNVFKSEINDNKDGNLNSHFVKGEIELKDVSFSYDSKKKILDNINLKI
                     KAGTSNAIIGETGSGKTTIINLITNFYHIDEGSIFLDGKDIYSINRNHLRTCFGVVPQ
                     EGYIFNDTVMENIRYGNLEATDEEVIYASKIANAHKFIVKMREGYSTVLSDRGEDLSE
                     GQKQLISIARAVLKNAPILILDEATSNIDIATEAKIQEAINNLTYGKTSIIIAHRLST
                     ISNCDNIIVLENGRIVESGNHKELIKLKGHYYRNILLTQGK"
     gene            complement(23151..24926)
                     /locus_tag="KRH23_002950"
     CDS             complement(23151..24926)
                     /locus_tag="KRH23_002950"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHS5226227.1"
                     /translation="MRYFKKYIKKYIVLFLTAVFFLTLEAFCDLAQPTIMAKIIDIGV
                     SNKNLDYILSTGAIMIGITFLGAIFAIIRSVISARVSQHFSYDLRQDVFEKINTYSLK
                     QIDKFGRASLITRVTNDINQMQQFVNGMMRVFIKSPIMCIGSLIIAIKLNLKMSIIIL
                     IAVLIIFIIILLNMKIGYRLFKNVQESTDKVNSKLRQFLSGIKVVKLFCRYDYENQSF
                     EELNDELFKNSRKATTMMSFFRPTITIIINVSIIIILLIGRHLIYSGEIKIGIIVAYV
                     NYMTRILTSLIMISHVFNVFVRAKASYERISEVLVDENEEVIEREESLDVGEKDLKFV
                     NCDIIFENVDFSYNKNTDEKILKNVSFKIEEGQNIGVIGQTGSGKTSLVNLIQKLYII
                     DKGDIKIGGRSIYSISEESLRERIGVVFQNSSVFGKSILENVVMGNRDICKEDVVKSC
                     EIANANQFITKLENTYDEVLFQRGKNLSGGQRQRITIARAIAKKPQILILDDCFSAMD
                     INTETIIRKNIKEYISNLREKESKKCTVITISQKISSIIDCDKILVLDEGEVVGFATH
                     EDLLVSSPIYKKIFALQNLVSEDVN"
BASE COUNT         8272 a         4338 c         2445 g        10021 t
ORIGIN      
        1 attaaatatg tttgtaattc tataaagtta tttttatcaa actaaaaatt ctataaaaaa
       61 ataagataca tacctatgaa atatcttcct atagatacat atcttaccta tataaaaact
      121 tattctatat aaaaacgcca taaaaaatct tttgcttctt ctgcataatc tatatttata
      181 cgtttactag tttttatatc taactcatct ttactaaata ctttttttcc tttatcatca
      241 taataaaaat cacttatata taattcttca cccattatac tcttactatt tagacttcta
      301 tctattttta aagctttgca aagttttcct ggtccgttag taatattttt tacttgatat
      361 ttactcaact cagtgtaagc tttgttgtat ctattcatag atatctcatc taaagaagtt
      421 ataggctcta cccctcttat taatacacac tctggcacat tttctatatt tgcagataaa
      481 tttaagcaat tatacatacc ataaattaaa taaacatata tatgtccacc atctaaatat
      541 aatggcttag ttctatctgt ctttttattg ccatatacat gtgctccttt atcatttaca
      601 cccatgtatg cttctgtctc tatgattttg gtaacaatta ctttattttc atatttcctt
      661 attagatatt tacctaatat tgatttggct aaatcaattc cattttttct aaaaaaatcc
      721 ttttccaaaa tttcacctca taaaatttat ttaaaacgca tcaaatacaa ctaaagtaat
      781 aaataaaatt aactcttatt aatgtgatat atataaacaa taaatttaga catttattat
      841 ttatatatat caaaaaattc tatctcaaac ttttcaatat tatcattgta atttgaatta
      901 tcatatactt cttcaacaac ctctttaatt gggaatataa cttttacatt agttccttct
      961 cctaccttac tatctatgta aatcttccca ttttgaattt caatcaatga ttttgtaagg
     1021 cataaaccta taccacttcc aaattcattt gatataccac tgttttcaat ttgtttaaat
     1081 cgattaaata tatcatttaa tttttctttg tctatgccca ctccagtatc ttttataatt
     1141 atctctactg tttcgtcttt tttatatata cctacaagga tttctcctcc ttctaaagta
     1201 aattttatag catttgataa tatatttagt attattcttt ctatcgattc tgggtcaagc
     1261 cctaccataa cagtttcttc atctgtatca aaaattaaat ctattccttt agacttagca
     1321 taactactaa tagatgtaac tattctttct gttatgtcaa taatatcaaa attaactgct
     1381 ttaatcttat atatgtctga cttaacttga gaaatattta ttatattatc tattaatctc
     1441 aataatctaa acatattttg tttagttatt tttatatgtt cttttagtat atcctgaaaa
     1501 tcaattattt ttcctttttt ataaaggttt tcaataagtt gaactgaact atatatatta
     1561 tttaaaggtg tcttaagttc atgagatata ttagcataaa actccatctt catttggtca
     1621 tactgtcttt gttttattaa tgctttttta agtctttcag actctctttg cacacttaaa
     1681 tctttaataa ttctcactct acttcttttc tgtccaaagt ataatgttct tgatatcatt
     1741 tttacttctt taatgtgatt attttcattt actatatgga tactcttctc tctttctcct
     1801 atatttaaat tgtttatgta tttttttact aatatatttc tatatttctg tgttgtaact
     1861 cctaatacat cactagaaat tccgaacaac tctctaaagg ctctatttgt atatagtact
     1921 cttgatgtac ttaaatcctc aagaaaaata gcctctggta taacatccag taatttttca
     1981 tatattattt tttgttcatt tactgttcta agaatattta tctctttagt tatatctcta
     2041 aatgtaagca atttaaagag tttattatct gaccaatagt ctccaactct aacttcttca
     2101 acatgttctt caccttctga gtcagacatc acaaaattaa ctatacagtt tgctgtgtca
     2161 ttgtaactta ctatttcagc tttcttttct tgtgttagat ttaatctttt aaattcccta
     2221 ttgtcaaaga aatctatgtt aaaagtttca aaatattgtt ctaatgtcat atcgactaaa
     2281 tcacttgaaa cacatttaaa actcttttca tattttttat ttatacttat taccttattc
     2341 ttctttatgc caccttcagc acttcttaca agtataggag atggaatatt tagtataatg
     2401 ttttcatagt ctttatttat atttcttatt tcttcatcta ttttgatttc atttgtaata
     2461 tcatttaaac ttattaagta attgctttcg tctttattat tacttaaact taacaaataa
     2521 attttatcat ttaactctac cagtttatca attatactta tatcgttatc aaatttcttc
     2581 aatttttcag caactttttc atcttccttt ataaaagtta atattttata ataattattc
     2641 atatcctttg aaaattcatc tttaaattta ttatttgtgt aacttatatt aaaatcatag
     2701 tctgttacta tccatacatt tggtattgta tccagagctt gtctaagtaa ttcttttctc
     2761 tggtctatgt agttttttaa tgttctttgt ataatcatat ccttttctat tgctaaattt
     2821 atctttccta attgctctga ctttttactt aattttttat tgattgaatc aagttcataa
     2881 tatggataca ctactctatt attaagactg tatacatata cataataagt atggttacat
     2941 aatagtaaat atattactcc tattaatcta tctgaatcta ctatattaat cttagaaatt
     3001 gctacaaaac atataatagt tgtaaaaaaa acaaaatatg ttaaatcttt tattaactta
     3061 tagtgctcaa tgttactatc aagtttattc aacaaatata gtaaattaaa catagatata
     3121 caaatattaa ttaatataat aatcatattc cagttaatat cactaaaaat atttcttata
     3181 aagtaatcta atatcacaaa agcactataa aaaattagta ttgggcttat tcttagtttt
     3241 tttactttag aaatggttaa gtatataaaa gtagacatat taattatgct taagttaagc
     3301 aatacaattt ggaatttttg aatttttaaa tttactactc ctaaaatact tacaaaaact
     3361 aatacaagac accctacttt caatatattt ataaattcat ctgttttaaa gctacttata
     3421 taaactatag aatatccaaa tatccaaagt aaaattattc tatacatatt tatagaaact
     3481 gtatacaaat ttatatttaa aagtgcaata accaaaaata acccattagc tagtatatag
     3541 accttattct tacttaaagt tcctttagat tccatattcc ccaccacttc ttcattttta
     3601 tatagtttta cctataaata tgttaccaca attcttccaa aaaatttgtc actttctagt
     3661 tataaaaaaa aatgagtaaa tatttttaat tttactcatt ttgtagattt tgtatattca
     3721 gtttaaaaag ctggaactat acttccttta tattcatctt gtataaattt tttaacttct
     3781 ttactattca tagcctctga taaagcctta atcttatcac tatctttatt attttctcta
     3841 caagctatta tatttacata tggagaatca cttgattcta ttactattgc atccttagta
     3901 ggatttaagt tagctgttaa agcataatta gaatttatta ctgctccgtc aacatctttt
     3961 aatactgttg gtaattgctc tgcattcatt tcttttatta ctatattttt aggattttta
     4021 gttatatctt ttttagttat aagctctcca tcttttactt ctatcaattt attttttgct
     4081 aataatttaa gtgctctagc tccattagtt gcatcatttg gcacagctat aacagctcca
     4141 tcttttaatt catctaatga cttaactttt tctgaataga atcccattgg ctctatatga
     4201 actttagatg tataagtaag tttatatcct ttctccttca cagtttcctc taaaaatgga
     4261 atatgttgaa agaagttagc atccaaagac ccttcatcta aagctgtatt tggaagtaca
     4321 taatcatcaa atatttttac ttctaaatca tatccttttt cttttaacaa aggttttgca
     4381 acttccaata tctttgcatg tggatttgat gaagctccta ctagtatttt tttatcctct
     4441 ttgtttgaac aacctactgc tgatattgct attgctgaca ccaatgctac tgataataat
     4501 ttctttaatt tcatttttac tccccctctt taaaatgttt ataattaatt tattttagtt
     4561 tcttataagc cagatttcct actccctgga ttatctgaac taatattata agtgctatta
     4621 cagtatatac cattactgct gtatcaaatc tttgatatcc ataaataagt gctatattac
     4681 ctaatcctcc agctcctact gcacctgcca tagctgtata accaagtata gatattattg
     4741 ataatgtaat tccagatact attgaaggca tagcttcctt tatcataact ttaaatacta
     4801 tttgtctttt tgtagctcca aaagattttg ctgcttctat caatccttta tcaacttcat
     4861 ttaatgagct ttctataatt ctagcgataa acggtgctgc cccaatagtt attggcacta
     4921 ttgcagcagt ttcccctata cttgttccaa cgattaatct agttattgga atcattgcaa
     4981 ctataagtat cataaatggg aaacttctaa atatatttac tataaatcct aatgcactat
     5041 ttattgtgct atttggtttt aatccatctg gttttgtaac tactaatatg attgctaata
     5101 taaatcctaa tattgttgcc actatagttg gtactataac catatacaaa gtttgtaaca
     5161 atgcatttgg aaatagtgtt gttaaaaagt caattaaact attcatttat catttcctcc
     5221 catcttatgc ccttactagt tagatattgt tttacttgct ctccactttt atctgaaatg
     5281 tttataataa gtgaacctaa aatatcatct ttaaattgtt ctaatttccc aaatattata
     5341 gacacatcta tatttagttc tcttgccata gtcgtaataa tagcttcatt agaaatatct
     5401 ttagggaata gtatctttat atttgttcct tttggcaata ttatactttc ttcacctatt
     5461 aattttctaa gtcctttagt atttcttaag aatatttctt ctgtatctcc tacctctaat
     5521 acttctccat tttccattat tgctactctt ccacaaatct gctttataac ttccatttga
     5581 tgagttacaa ctattattgt tattcccaat tttttattta tatcttcaag caatgaaaga
     5641 attgactttg tagtatttgg gtctaatgct gaagtcgctt catcacaaag aagtacttgt
     5701 ggatttagtg ctaaagctct agcaattgca accctttgtt tttgtccgcc acttagattt
     5761 ctgggtttat catttttctt ttcagatatt ccaactactt ctaataactc taaaactctt
     5821 tttttaattt ctgcctttga gtatccaaaa cattctaatg gcaatgctac attatcaaat
     5881 acagtttttc tttcaagcaa tgaaaagtgt tgaaaaatca ttcctaactc ttttcttaaa
     5941 tctctcattt gcttttcatt caatgacttt acttctttat cagaaacaag tacactgcct
     6001 tcttggtatt cttctaatcc gtttatacat ctcagtagtg ttgatttccc tgcaccacta
     6061 tgacctatta ttccaaaaat ttctccagat tctatttcaa tacttacatc tttaagcact
     6121 tgaatctttc cataatactt attaacattt tttatgctaa tcataaaatt tcctcccata
     6181 tattctgctc agtttttatg tttatcctct cttatgtatt acaacaaaat aaaagcccga
     6241 gtataaactc aggcttagaa agctatttat actcatctat caactatatt agttgcagga
     6301 tttagcacca atgtatataa aatatactgg ttgccgggtt tcaaagggcc agtccctcca
     6361 ccactcttga taagacgtta tttaatttaa ttctattatc atttgttgct atgttatata
     6421 tgatatattc attaatagta tttgtcaata aatttattta aattttttat tttttattat
     6481 cgttaattaa ctatttttaa ttagttttct agctcctaac actttatatt ttaatgtcta
     6541 tataactata gaacatcatt ataagaaata aattaaataa catcaatcta tctaaatcat
     6601 ctgtaaagta aattaagaaa attaacattt tatccaaact ctatcctact attaaataaa
     6661 ataatttaaa tacaatgatg attatatagc tctagtactt tagactttat caaatgttta
     6721 agttctatag gttctattat tgtagcattt ttcccaaaag ttaaaaaata ttcagccacc
     6781 cagttaagtg tagattttgg tatatacata tctatgtatc cacctttaga caagattttc
     6841 aaccctcttg ccaacaaaaa ttctgtttca caacgtttta ctccctcatc tgtcaaatta
     6901 attttaatat gataatctgt acctacttcc atattcttaa gataatcatg tatagaagat
     6961 aaaaccttat atttcttact tgataagttt tctatactca aaatcttcac aattctgtct
     7021 acacgaaatt ccttaataga ttctgatttt atacagtaag ctggacaata ccaaagtcca
     7081 ttcatggcat acaaaccaat aggaacaatg gtacgtacac tatttttttg ctttgatgaa
     7141 tattcaattt taattgtaaa ttcattcatt actatattaa acaattcttt caataatggt
     7201 gttgaacagt gcctatctgg tgtccaaaaa acaaatttac gccttatatt ctcaatatta
     7261 tattgaatat catttggtat acaatttaaa aattttttta aaacagaaat agtttcttgc
     7321 tcaaatggca aatcattata atattctagt gactgatatg caaagaatat agattttacc
     7381 tcactttctg aaaatgcaat cggtggaagt atacgctctt taagtacatg atatccacca
     7441 gccgctccaa cttttgaata taatggaaat ccaatactct ccagcacctg taagtctctt
     7501 agtatagtac gttttgatac agaaaattct tctgctaatt ctcctgctgt aaaacttctt
     7561 tttgcattta ttgttatcat cagttcaatt aaacgctcag ctcttgacat atttatactc
     7621 ctaatttaaa tatagtgaca ataattgtca ctattatatg ataagatatt cttacattta
     7681 aagcaataat aatagtaaag aaagaaggga ctgatacttt atagaaaata atactattaa
     7741 ggctgatgat attatcaatt attgtctatc aaacttagat gatgttttat taatgaatag
     7801 ttggggggaa cgagcaattt actacaatcc taatggtatt ttaaagcgag gagtatatgt
     7861 tcttaccatt aaagaaaaag acagtaatca tgataaaggt tcgttggtta gtcgtccaaa
     7921 tgtataccgt gtgaatatag gattaaaaaa agaaactttt attgaaatgt ttggatatat
     7981 tccaaagcgt ccaggtgtag gtcaaatagt tgatatggat tttgatttta caaaattgga
     8041 cacaatcatg ccacatccta tctactcatg gatgggatgg atatgcatcc taagccctac
     8101 tgaaaagaca tttgagaact ttaaaacttt aataggagaa tcttacaatt ttgcaaaaca
     8161 aaaatttaaa aagagaaaaa acaagtaaaa acatatgaaa ataatcccta aataaattat
     8221 aataaaaata ttaaggttac aagataaaaa ttaatatctt aataacatgc aaaaaagcga
     8281 agccaaaaaa tgtattattt ataaggcttc gctatatctc aaataattta tttcaaattt
     8341 caaaactatt tattctatta tttcttatta tttcctgtta ttcctaatct atcattcata
     8401 tcttttatca tttttctaaa accactacct atatcatttc caacatcttc agttccatga
     8461 actaatttta taaagtcatt ttgacctttt ttcatatctt catcagatac cttatctaat
     8521 ttttctattc tcttatctat gtcttttact aatctttccc cttcagcgat taggtcatca
     8581 ttcattttct ttaactctgt atcttctgtt ttaccatctt ttttaagaga tgttacaaat
     8641 gattgtattt tatctctact atctttatat gcagccttta catcacttag atatttttca
     8701 tttcctggat attctttatc tttaaactga ttatttatac tttctggagt atcataaata
     8761 gaatatctat ttagacctgc tatataatca ttatagcttg ttgaataata attcatatat
     8821 ccttcattat tatttacaga ttcattagga ttttttcctg tattttcact tggtttttca
     8881 ttatttttag tacatgcagt tatacctata gctaatacta gtgctaatcc tacaaataaa
     8941 gttcttttta atttcatttt tattaccctc ctagatgttt tatactataa aaaattttaa
     9001 taattttctt tcttaattta gtatttctat atttttatat tttatttact aaaattaaac
     9061 aagttataat ttattttttt ggaaatcata atgaataaat aattaaataa aaaaattata
     9121 attttattat tgatattgat tatcattcat agtataatct aattacttga tattaatttt
     9181 catttgaagg aggttatctt ttatgtcttg ttgtaattca caattttgtt gtaaaaataa
     9241 aattgaatca tcatatataa aatggctttt agaagtttta ggtccagtct ttttaggctc
     9301 taaacctgct gaaataataa atatttcgtt tactgatgta aatagagagg aaaaaattaa
     9361 tgatatttat aaatatctat ataaatgtaa gaaaatagat tttatagtta ttgataaaga
     9421 aaaaaaggga ttaaaaatct tatttgtaaa taaaaaagca ttatcagaaa aattaaaatg
     9481 taaaaaaaca gtaaactttt taaagttttt aggatacaaa caaaatacga atgttaatgc
     9541 ttatttagag catttagtag ataaacttaa gagtgatgtt tttcctgatg aaataggtat
     9601 ttttttagga tatcctctta aagatgtgat tggatttatg ggatatagta attatgaagt
     9661 ttctatgatt aaatattgga aagtttatgg tgacacaaaa caatccgagg acacatattc
     9721 gaagttttta cttcaccgta agaaaatgag aaaattacta gactacataa gtgtagataa
     9781 aatagtaagc tgtttttaat tatgtttttg tataataata aaaatacacc ctcttttacc
     9841 atacagtttc cataataaat aagggtgtat tttccacttt aatattttaa agtattctaa
     9901 ttttgattgt acaacatatc tttaatattt attttctttt gttgcattcc attagacatc
     9961 aaaaattcct gtgtatcttc taattctttt atatccttgt ccgttatttt agaactaaag
    10021 tcataccaag aatacatttc ttttgtttca tctaaagata aaccaacttc tttagataca
    10081 acatccatca cttcatcctt gttttcattc atatatttta aagtttcttc atgaaccttc
    10141 ataaatcttt ttactaattc aggatatttt tcagcaaagt catcacttac agcagtaact
    10201 attattccac ttactaatcc ttctccattt acaatcattt tggcacctga atttatcgtt
    10261 ttcaatgcca ctggacctgc aagcattgct acatcagcac ttttactttc taatgcagaa
    10321 gcagcactag gaatatccat atttacatat tcaacatcat ctatagtata gccttcttta
    10381 gcaagtgcag caatcaacag ttgatgaagt atagtccctt ttggacctac aattttttta
    10441 ccttttaagt cttttataga tttaatatta tcattattag ttataagcat atatcctttt
    10501 ggtgaacggc tataaatatt cgtaatttta agaccaacac catttgatgc agctattatt
    10561 gcagacgttc ctcctaatgc atgtaaaaag tctagctcac ctgctgctaa tgcttgagtt
    10621 tgctctggtc ctgttgtcaa ttcatggaag ttgactttta tattgtcctt tttaaattcc
    10681 tttccaaata aatcatcctt tttttctaat atactaggaa cattaagtgg tgattttaca
    10741 taagttaaat ttatttcctt aggtaaacta gcctcttttt ttgcaggttc atctttctta
    10801 tcatttgttg ttgaacatcc tacagtccca accaacacca ttattaaaga tgtcattact
    10861 gctaaaatct ttttgtttct tttaatcaat taaaactccc ccaattccct taatatttct
    10921 tttttcaagt ttatataata gtttttagtt aaatctctat tatattcatc ttcgacacta
    10981 aattgtttaa tccttttatt tttactaaaa acaattattt tctttgctat ttccatagct
    11041 tcttcaatat tgtgagttac aaatactaca ccttttttag tatttttatg gatatttaca
    11101 acttcttttt gcatttttct tcttgtgaag taatctagtg ctgcaaatgg ttcgtccatc
    11161 agcaaaatat cgggattgaa ggaaagtgct cttgctatac ttactctgtg agccattcct
    11221 cctgataatt catttggata tgagttttta aacttttcaa gcttcatcat ttttaaatac
    11281 ttgtctaaat caactttatt tctattatct ttttcagtat gtaaaagtat attttcactt
    11341 acattcagcc atggcataag tctactttct tgaaatacca ttcctacttt tggagtacac
    11401 tttttatcat tattaaaaaa atatatgttt ccactagtag ccttttcaag ccctgctaaa
    11461 attctaagta gcgttgtttt cccacatcca ctttcaccta atataacagt tatctcttca
    11521 ctagatatat ttaaagatat attatcaaga actaaatgct ctttattatc aactaaatat
    11581 ttcttatata tattctctag caaaaatcca cttctaacca tttaaatcaa cctgcttccc
    11641 tttgctaaat tttgttatta tctttgaaaa tagataatct gaaagtatac ctaaaaatcc
    11701 aataacaaaa attcctacca atacaacatc agttctagac atatcttttc catcagaaat
    11761 caaatatcct agtcctgaag aagctgcaat aagctctgct ccaattatag ccctaaaact
    11821 atacccaagc cctaaactaa gtccaacaac aatatccagc atagaattag ggattattat
    11881 tttataaaaa attctctttt tagataaatt aaaagattta cctacttcta ttaatttatt
    11941 gtcacaattt tttatacctt tcaatgtatt taaaaatatt ggaaaaaagg atgccaaaat
    12001 aataattata attttagatt cttcacctat accaaaccat aaaataagca ttggcaccaa
    12061 agctagtgga ggtgtacttc gcataaattc aaatagtggt ttgaaatact catacatttt
    12121 tttatttact ccaaataaaa ctccaagtgg tatagccatc aatgaactta ttaaaaaacc
    12181 tattaatatc cttcttacac tggcataaac atttaagaaa atagaaccgt catatatcat
    12241 ttttataaaa gtatctaaga ctatttcagg aggaggcaga atatagctac tccatatacc
    12301 caaaacacat actatcttcc ataaaattaa aattattaaa aaaatataat atcctttaag
    12361 ccttttatga attttctcaa acatataaaa ctccttttaa catatctatc cctgctaccc
    12421 tttttatttt ttaatatctt aaataataat taagctatat cataagattt aatctatgcc
    12481 aagtcttaat ccacctgaac tcattctatc agaaggtgta gaatctgttt ttaagccaga
    12541 caatctttca gatggttgta taatgactat ttgtccaggt tcaacaaatt ccatatgata
    12601 agattctcct gaagtctgac caataaaagt cttccatgat agttttgata ctttaggata
    12661 tggttctctt ccagtccaag ctactaatgc atctgggtca acacaacaag gtccttcaag
    12721 aattagagga ttaccatctg ttattatagc aacatcttga ttttgacctg ttttatttac
    12781 taaatgtgta gtaaaaagac ctttttgaga tattacccct gaaccaatca attttacact
    12841 gtaatttaat tgttcagaaa atgccaataa gttttcactc tcaacataaa tggaatcacc
    12901 tgggtcaatt gatattacat ctacatggta agcattttga gctaggtaaa tttcaccttc
    12961 accttcaacc accattattg gcatttgttc tcctgtcaat gacctctgaa catgacctaa
    13021 taatgctctt cccaatccac cgccattact tggacctaac agcaattttt caaaattaaa
    13081 atttccttta aaggctacca tagcaccttt ttttgcaaaa aatttaccac ttccccttgc
    13141 tatacacata agctcgtttg taacatcaaa tttaaacata atattcactt atattgctta
    13201 atttagcaat aatccctcct aatcatatat ttatatataa ttatacagta aaattacagc
    13261 atagtctaac ctacttcaaa tatgaaattt gttatttata taaaaaataa gaacctgata
    13321 ataaagcaat ttaacttttt atcaggctct tatcctattt atctcttagc gctatgacaa
    13381 ctcttactac ttgagcatcc agaacaacca catccacaac tgctaccatt cttttttgaa
    13441 tttttaacca tatacattac agctagtgcc attaatacta ctacaatagc tgctataata
    13501 aatgtagcca tattcatcac tccttattta tatgaattaa tttttcatat aacttaattt
    13561 acccattttt tcttttttca tatttttatt tgaataagtt aaaactacaa agactactgc
    13621 tactgctata aatatagata ttattgcccc agcaatactt cctccagtac ctaaaactaa
    13681 acttccaact tgatttataa gaagagcaat tatatacgct gttaaagttt ggaatcctaa
    13741 tgtaatccat gtccatttcc atgaacccat ttctcttttt atggctccaa tagctgcaaa
    13801 acaaggtgca caaagcatat taaatgccat aaatgcaaac gcactagcta ctgtaaacat
    13861 acttgcaact gaagcaagaa gtgttgggtc ttgctctgtt gcatctgata taccaaataa
    13921 aactccaaat gttccaacta cattttcctt agctactaga cctgtaactg ttgctactga
    13981 tgattgccaa tttccaaatc caagaggagc aaatattggt gcaactatat ttcctaagct
    14041 agctaatata ctatctccag catctaccat ttgtaatgac caattaaatg attgtaagaa
    14101 ccagattact ccacaagcaa caaatataat tgttcctgct ttgattataa atgcttttcc
    14161 tctatcccac atatgtatta aaacaccttt tgcacttgga atatgatatt gaggtaattc
    14221 cataacaaat ggagatggtt ctcctgcaaa taaactagtt ttctttaata taattccaca
    14281 aatgattatc attgcaatac ctaagaaata cattgatgga gctacccatg aagcacctcc
    14341 aaataatgcc cctgcaaata atgctattat tggaatctta gctccacatg gaatgaatgt
    14401 agttaacata atagtcattt ttctatctct atcattctct atagtacgag ttgacataac
    14461 tcctggaact ccacaacctg aacttataag cattggtata aatgattttc ctgaaagacc
    14521 aaacttacgg aaaattctat ccattataaa agctacacgt gacatgtacc cacaatcttc
    14581 taatattgat aataataaga ataaaagcat gatttgtggt acaaatccta gtactgctcc
    14641 aactccacca attagaccat caactacaag tccttgtaac cactctgcta catttaaaga
    14701 agctagaaaa ttacttacat tgccttgaat aatttctcca aacagtacat catttgtcca
    14761 atcagttgct atagtaccca atgaacttac tgctatatag taaactcccc acattataag
    14821 tgcaaaaata ggtaatgcta gtatacgatt tgttacaatc ttatctatct tatctgatac
    14881 agtttcctta ccttttcgat tcttctttat tatacttgaa attattgaac taataaattc
    14941 ataacgattg gctgttatta tactttcact atcatcatcc aattcatctt cacaatttct
    15001 agttatttct tcaatactat tcaatattgt tttagaaata tcaagttttt gtataacatt
    15061 ttcatctctc tcaaatagct ttatagctaa ccagcgtgtt tctacatcta tatatggagt
    15121 cttttcttct attatttttt caattttttc tattgcatcc ttactttcat caacaaaggg
    15181 taatttgaaa tttaatttat tgttactact tgcaagttca actgcctttt cagcagcctc
    15241 cataattcct tgacctttaa ctgctgttac ttctaccact gggcaaccta taacttcaga
    15301 tagttcttta atatttatct tatcaccatt cttatttaca atatccatca tattaagagc
    15361 tataacggtc ggtataccta gctctaaaac ttgagttgta agatataaat ttctctctat
    15421 atttgatgca tctacaatat ttattactgc atccggctta tcatctagca taaaattacg
    15481 tgtaactact tcttctaatg tatatggaga taaagaataa atacctggta aatctactat
    15541 ttccacatct ttatttcctt ttaattttcc accttttttt tcaactgtta ctcctggcca
    15601 gttaccaaca tattgtgatg agcctgtaag cccattgaac attgttgtct taccacagtt
    15661 aggatttcct atgagaccta tttttattga catttccatt ccctccatta ttatttaaat
    15721 acatcactgt ttgtgataca gaaaatcatt ctcattatat aattacatta acccttctct
    15781 aattaatctt tattattcca caataatttt ttctgcatct gacttacgaa ttgatagttc
    15841 ataatctctg actgttacct caattgggtc accaagagga gctacttttc ttataaagat
    15901 attaacacct cttgtaatcc ccatatccat tatacgtctt cgtgtagctc cttctccttc
    15961 taactttttg acttttacag tctctccaca cttaatatcc ttcagtctgt tcatgtcatt
    16021 acctccctat attattattc tacttgccat ttttttatct aatgcaactc tagtatcttt
    16081 tacgtctatt attaagttac catctatctt agaaactatt ttaacatttg tacccactac
    16141 aaaacctata ctatttaaaa aagtcctcgt cttatcactt cccgaaattt tctttataac
    16201 tacttcttca cctgtatttg ataatatcaa tggcatcata taatatccct cctcttaaag
    16261 taatttaaat ctacaagcaa tcgttatctt atatataaat tacaatacct taaatcttaa
    16321 tctattaaaa taatatccta ttttttcctt ctttttacaa ttcctaattt tgatttaagt
    16381 ctatcacaat agtatatttt ttgcaagtga ttattgtatt cttttgattt tttttctcat
    16441 ttgatttatt ttattaataa aatcgtaaaa attaatacaa aaataaagat gctctaaaat
    16501 agtatactca actaatatta aagcaccttt attatatatg tcattattta cacattgctt
    16561 tattcttttt taaaagcgat tttttcaaac tcttttacag gcattggctt agaaaacaaa
    16621 tatccttgta ccatatcaca cccaatctgc tttagaaatt ctacttgcga aatagtctct
    16681 acaccttctg atattacttt cattttcagt tcctttgcca ttttaatgac attagatata
    16741 acaatttttt cattattact ctcatctttt tctgtaaaaa atgctctatc tagttttaat
    16801 atgtcaacag gcaattcttt taaaagatta agagaggaat atcccgtacc aaaatcgtcc
    16861 atagagatta caaatccctt ttctttcaaa ttgttcattg tatcaagtaa tccttctata
    16921 ttatctaata ctgctgtttc tgttagctct aattctataa gtcttgtcgg aattttgtat
    16981 ttatctacaa ttaatttaaa cttctctata aaattactat ttacaaaatg cattcgagac
    17041 aagtttacag atataggtac tactttttgt ccttcatcca tccattctct aatcttttta
    17101 cacacttcct caaatacata gaaatcaata tttacaataa aaccattcct ctcaaataca
    17161 ggaataaatt ctattggtgg tattagacct ttttgtggat tatcccaacg aacaagagcc
    17221 tctgccccta taatttgata atctgaaaga ctatatttag gttgaaaata aacaataaat
    17281 tctccattat taagagcatc taccattgaa ttttcaattt ctttctcttt taatattttt
    17341 ttgtgcattt ccttatcgta aaaagcaaat gaatttttat gaccaccttt tatagttttt
    17401 cttgcagtat tagctctatc cataatagta tttatgtcat tatcactttt acttatttta
    17461 tatataccac aatctaaaat caatttataa tagtttattt taggattact aagtatttga
    17521 accttattgt aaatattgtt taaccttgtt ttaatatcat catctgtctt atacttaata
    17581 agaagaacaa aatggtcagc agaaactctt gcaaaaattt catcttcctt taattcactt
    17641 gcaatagtat ttgatatatg tatcaaagta tcatttccca tatcatatcc aaacatatca
    17701 tttatatatt taaatttgtc aacatctata taaaacaacg catattcttc tggattattt
    17761 ttagcaaaca gtttgttaga atttatttta aatttatcta tactatctgc tcctgtcaat
    17821 gggtctgtat atgctatctt ccttagataa tcctctttct tctttttatt ataaattata
    17881 tatttaatag caattaagaa taaaatacat acaaaagaaa taatttgtat tgaatattct
    17941 ttaaaaataa caccaaatgg tactttataa ggtttgtcaa tagtattaga atatatacaa
    18001 tcacttaatt cttcttcagt aattttgtct attgatttat ttaaaataga cactaatata
    18061 gggtcagttt tatttgatac ccctatacgc atcccatagc ttgtatctaa aacagatata
    18121 acagataaat tctcactctt tccttctctt aaaagttcat caaactgata agaactaagt
    18181 atcattaagt ttgctttacc ttcatttata gcgtttagac aactttctac actcttataa
    18241 gatgttgtct tagcattttc aaaactcttt tctatataag aatcaataga cttataacta
    18301 ctagttaaag caatatttaa atcattattg agattggtat ccaattttcc taccataatc
    18361 attggaatat ttatgtatgg atttgtcaat ttcatattaa atcgttttgc cttatcattt
    18421 tcattgattg agccacatag catagttgcc ttaccacttt ttatgtaatc aagactctca
    18481 ttataatttt ttgttttaat atattcaaat tttataccac atttttttga tataattgac
    18541 attaaatcgg aacttatacc tttaaatgaa ttgctttctt tatcataata ctctacagga
    18601 gaccactctg aatcatatac catagtaagt tttgggtttg ctttaataaa attcatttct
    18661 tgccgagtaa atgctatgga attattgacc tctcttttga aatatttttt atataattcc
    18721 aattcataat acatatcatt tatttttaat tcttttaaag cataatctaa ttcttttacc
    18781 aaattaggtt tatcttttgc agtagcaaaa taaaaaggtt ctactgaaaa tttgctaact
    18841 attttcattc ctttagcatt tataatactt ccacaaacaa atgcatctgc ctttttttca
    18901 ttgacggact caattaattc atcaatagaa ttacagtata tatattcaac tgaaaaatta
    18961 ttttcttctc tatacttctc aaatgcagta ttatgaaagt ttcctctaag tacagctact
    19021 ctcattccct taaaggaact tatatcttca taaaacatat tattgttact atcctttgta
    19081 tatagtgcac tatattcata tcctgaactt agtttaggaa aattaaatag tttatttctt
    19141 tcatcattct tctgtaaagg tccgagtaag tctatttcac ccttttctag tctgtctaaa
    19201 cattcttccc aagacccttt tacaaattca tattcccatc ttgtatattt tgagatttct
    19261 cttagataat cataaccata tcctgtataa gaatgctctt ttgatgagga tattattccg
    19321 tagtcatcac aatatccaac tcttattttt tttgaatttt cagactcatc agcaaagcat
    19381 agtatattgt taaaacatga tataataagt aaaaatatca aagaaagtat caagaagtgc
    19441 tttttaaatg ctttcatatt taaaaacctc caatttgcca acttacttta acttatttgg
    19501 ttttctagtt gtaactactt ttattgtaat ggtaaatata tcaaattgca atattctcat
    19561 ataatattct tattcaacta taatgaattt attattatct atttaaatac actatctaat
    19621 attagtttct tataagtcat aaaagcacaa ctaacactat aattctagtg attaatttta
    19681 tttcaaaaaa tataataaca ctactaatat tttaaatatc aatagtgtca taaaaacttt
    19741 tcagattaat taaatctttc tatatatttt ataataatct aaatcatgct aaatatttag
    19801 acagaaaact tttttcttta atagtaaata cttttgtttg aatatcagaa taattatttg
    19861 aatatctatc tataaaacca tgatttgcat ctaaaatctc aatttggata ttttgtttcc
    19921 tagaaagttg gtaagaaata gaatcaacat caaatgaatc gtgctttgca aatactaata
    19981 aggtaggaca ttttggaatt acatccatgt aatctcgaat ccgagagcca taacaacaaa
    20041 ttatgccatc acaaaaagaa tcttcactgc atctccatgc aatagttgct cccacgctat
    20101 acccagcaac aaatacatat ttatactctg attttaaatc atttataagc ttttcaactt
    20161 ttttataaat atcaaaacca acattattta taaaaaaatc atatgcctct tggacttttg
    20221 aatatggaaa aactcttttt tctcccagaa gttcaggaca aaatacatca tatccatatt
    20281 tataatactt ttgacaaaca tcttctataa agctattaat cccatagatt tcatgcaaaa
    20341 caacaatagc tacatcactt ttatgtatat actttatcag attatccacc acctttacaa
    20401 aacagcaaat tttttatact tagtttaata tattcttctt tacatgtcaa tttacttttc
    20461 taaaatcaaa tttatttttg gattaatcat ttatttttaa aagttgtgca ttattactat
    20521 taaattattc tctattatta aaaatataat cgttagaaat aaaaaataaa gtacaaataa
    20581 ttaaaaaata tctcactcat aactttaaaa attataagtg agatactcct aaaatctact
    20641 ttatattaaa tttattttcc aaaatatcta tttaataatc ctaagaatgc tttaccatgt
    20701 ctagcttcat ctttacacat ttcatgtact gtatcatgta tagcatctaa tcctaattct
    20761 tttgctttct tagctaattt taattttcca tcagttgcac catactcagc atcaactcta
    20821 actcttaagt tttcttttgt atctgcaact acaacttctc caagaagttc tgcaaattta
    20881 gcagcatgtt cagcttcttc aagagctatt ctcttataag cttctcctac ttctggataa
    20941 ccttctctat cagcttgtct actcattgct aaatacattc ctacttctgt acactcacca
    21001 acaaagttag ctcttaatcc ttcgattatt tcttcatcta caccttgagc tactcctatt
    21061 ctgtgctcat cagcccaatt tttttcgcct ttcatttctt caaatttatc agctccaact
    21121 ttacatactg gacattgtgc tggtgcagca tctccttcat gtatatatcc acatactgta
    21181 caaacaaatt tcttcataat tactttcctc ctaaatttta tatatcaaat taaatttttt
    21241 atttattaag ttagtctata tatacccgca ccatatacct ttaaacaatt tttttaaaag
    21301 ttttttctaa atacctattt tccctgtgtc aataatatgt ttctataata atgtcccttt
    21361 aattttatca attctttatg atttcctgat tccacaattc taccattttc taaaactatt
    21421 atattatcac aatttgatat ggtacttaat ctatgagcta taattatact tgtctttcca
    21481 taagttaaat tatttattgc ttcttgaatt ttagcttctg ttgctatatc tatgttactt
    21541 gtagcctcat ccaaaataag tattggagca ttttttaata ctgctctagc aatacttatt
    21601 aattgttttt gaccttcact taaatcttca cccctatccg ataatacagt actatatcct
    21661 tcacgcattt taactataaa tttatgtgca tttgctattt tactagcata tataacttct
    21721 tcatcagtag cctccagatt tccatacctt atattttcca taactgtatc attgaatata
    21781 taaccttctt gtggaactac tccaaaacaa gttctcaaat ggtttctgtt aatagagtat
    21841 atatccttac catctaaaaa tatacttcct tcatctatat gataaaaatt tgtaattaga
    21901 tttataatcg ttgtttttcc acttcctgtc tctcctatga tggcatttga tgtgccagct
    21961 ttgattttta ggtttatatt atctaaaatt ttcttttttg aatcataaga aaaacttaca
    22021 tctttaagct caatttctcc ctttacaaaa tgagagttta aattaccatc tttattatcg
    22081 ttaatctcac ttttaaacac gttatgcact tcttgctctt cttgttcatc tataatttca
    22141 aaaactcttt cacatccaac tatggctgaa agtaatgtat taaataaatt tgccaattca
    22201 tttaaaggtc ttgtgaattg tcttacataa cttaaaaaac tagctataac ccctatggtt
    22261 ataatatctt tagatgcaag aacgcctcct ataatacata tggttgcaaa tcctatatta
    22321 ctaatcacat tcataatagg cattaaaaga gaagtgtaaa tttgtgattt aagggaaata
    22381 tttagaagtc tatcattgac ttctttaaaa tcatttacag attttctttc ataattaaaa
    22441 gattttacta catttatgtt tgatatcatt tcttcaatat gtgcatttag ttttcccaac
    22501 tcaacttgtt gttgcttaaa aaaaactcta gttctctttg caataaaatt actcacaaac
    22561 attactatcg gtattaatat tatactgcaa aaggttaaaa ttggacttaa tacaaacatc
    22621 ataataaaag tcatcaatat gtttaagatt cctgtaatta actgtactaa tgaatttgat
    22681 attcctgtac tgatattatc aacatcattt gtcactctgc tcataatatc tccagtagaa
    22741 cttttatcaa aaaaggttat tggtagattt ttaaatttta aaaataaatt acttctcatt
    22801 tctctgacta tactttgaga taatctagct gtacatatcc ccttagacag tttaactgaa
    22861 aactcaatta tataaaatga aagtaaaata attattcctt ttaagaaaat ggattttgaa
    22921 taagtatcga tatctattat gtcaactact tttccaatag tatatggtat tacagttgat
    22981 ataattgaat caattattac tagcaaaaaa ataaatctag taatcttctt atctttttta
    23041 aagtacataa aaattctttt aaacgttttt ttaaaatctt taggcttttc ttttttcttt
    23101 aatctactga ccttttgatt tccagtactt aaattcaata tacttcctcc ttaatttaca
    23161 tcttcactta ctaaattctg caacgcaaaa atttttttat aaattggaga actaaccagt
    23221 aaatcttcat gtgtagcaaa tccaaccacc tcaccctcat ccaagactaa aatcttatca
    23281 cagtcaatta tagaactaat cttttgtgaa atagttatta cagtacattt cttactttcc
    23341 ttttctctta aattacttat atactctttt atattctttc ttataattgt ctctgtatta
    23401 atatccattg cactaaaaca atcatcaaga attaatattt gtggtttttt ggctatagct
    23461 ctagctatag taattctttg tctctgtcct cctgataaat ttttacccct ttggaataaa
    23521 acttcatcat aagtattttc gagttttgtt ataaattgat ttgcatttgc tatttcacat
    23581 gattttacaa catcctcttt gcatatatct ctatttccca taactacatt ctccaatata
    23641 ctttttccaa acacactact attttgaaat actacaccta ttctttccct taaactttct
    23701 tcagaaatac tgtatatact acgtcctcca atcttaatat cacctttatc aattatatat
    23761 aatttttgaa ttaaatttac taaagaagtc tttcctgaac cagtttgacc aatcacacca
    23821 atattttgac cttcttctat tttaaaggat acgtttttta atattttttc atctgtattt
    23881 ttgttatacg aaaaatctac attttcaaaa attatatcac aatttacaaa ctttaaatct
    23941 ttttctccaa catctaaact ttcttctctc tcaattactt cttcattctc atcaaccaaa
    24001 acctcactta ttctctcata agatgctttt gctctaacaa aaacattaaa aacatgtgaa
    24061 atcattataa gagatgttaa tattctagtc atatagttta cataagcaac tataatccca
    24121 attttaattt ctcctgaata aattaaatgc cttccaatca gtaatattat tattatggaa
    24181 acattaatga ttattgtaat tgtcggtcta aaaaatgaca tcatagttgt agcttttcta
    24241 ctatttttaa aaagttcatc atttaactct tcaaagcttt ggttctcata atcgtatcta
    24301 caaaatagtt taactacttt tattccactt aaaaactgtc ttaattttga atttacttta
    24361 tctgtacttt cttgtacatt tttaaataat ctatacccta tcttcatatt aagcaatatt
    24421 ataataaata taattaaaac tgcaattaga ataattattg acatctttaa atttaatttt
    24481 atagctataa ttaaacttcc tatacacatt attggtgact ttataaaaac tctcatcatt
    24541 ccattaacga attgttgcat ttgattgata tcattagtaa ctcttgttat taatgaagct
    24601 ctaccaaatt tatctatttg ttttaatgag tatgtattta tcttttcaaa tacatcctgt
    24661 cttaaatcat aagaaaaatg ctgagaaact cttgccgaga ttacacttct tattattgca
    24721 aatattgcac ctaaaaaagt tatacctatc attatagctc ctgttgatag tatgtagtct
    24781 aagttcttat ttgaaacccc tatatctatt atttttgcca ttatagttgg ttgagctaaa
    24841 tcacaaaaag cttccaatgt taaaaaaaat actgctgtta gaaataatac tatatatttt
    24901 tttatgtatt ttttaaaata cctcattcaa tcatcccttc atagaatttt ctcattacca
    24961 aaagtatatc ataatggcta atttaattga ttatatcaat tataaatatt tgatttatta
    25021 ttaattttta taccatatat tttataaatt atttgttttt atttcctata tttata
//
LOCUS       DAEORM030000056        24160 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.056, whole genome shotgun sequence.
ACCESSION   DAEORM030000056 DAEORM030000000
VERSION     DAEORM030000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 24160)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24160)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 24160)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24160
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.056"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            13..2190
                     /locus_tag="KRH23_002951"
     CDS             13..2190
                     /locus_tag="KRH23_002951"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0043546 - molybdopterin cofactor binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-containing oxidoreductase family
                     protein"
                     /protein_id="HHS5226228.1"
                     /translation="MYNKYNNLYLLLGKENVNMDSYRQLKAKIPCKETGIEIKRTLCD
                     ICSPGVHCGIDAYVKDGKVIKIEGTKEHPMNKGLLCTKGLCNREYIYREDRIKTPLKR
                     IGKRGEGKFKPISWDEAYREIAEKLNRVKSEYGAKHVAFFTGYGKWYRPFLQRFASSF
                     GSPNYGTESSSCSTSAQMAGNVATGRNFTMQDMENAKTYLGWGFNPYYSKFLNSVNLI
                     KLKEKGLKFIIVDPRITPTTQKLADLHLRIKPGTDGALALGMANLFIQKDLIDREYIE
                     KHVHGFNEYKEYVKLFDLDTVSRITGVSKDNIVKAVEMLSQGPFCINESAAPIVHHQN
                     GFQNYRAMMSLSAITGNYDRIGGNIPKQDYFAGKIGGFQTLEKEFVKEVLPKNINERI
                     GGERFPLWNEMVTQFQAMDLPRQIEEKTPYEIRALFCHGINARMFPNSGRLFKALNSV
                     DFFVNIDLFMTDTSKYADILLPACTSFEREECKSYPGGYITYTKKVIDKLYDSKSDVE
                     ILSDLANAMNIDDDLLKAGYEASIRHMFKNTCVDVDKLKESDLPLKCKDFKPYIVGSY
                     TREGYDTSTSRFELKSTIIEKYKDFGLDALPTYRGFNDNIDDEYTHLLTSGARISNAL
                     HSRLHDIKLSRILKNEASCDISSLDAKELGVISGDYIKITTKIGSLDVKVNVTDRVLY
                     KNIHMYHGYREADINSIICDNFDPYSGFPAYRSCKCKIEKMNR"
     gene            2204..2626
                     /locus_tag="KRH23_002952"
     CDS             2204..2626
                     /locus_tag="KRH23_002952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HHS5226229.1"
                     /translation="MKSLFKFNKELCTACGACLLACIDQNDNNIDNGELFRHVFTIEE
                     GENIEYFSLACIHCNEPKCLGVCPKNCFKREEGFIVLDNQNCIGCKLCEKACEYGALI
                     YGNDGKANKCNGCIERYKCGMDSPCVMVCPTGALKFNK"
     gene            2800..3375
                     /locus_tag="KRH23_002953"
     CDS             2800..3375
                     /locus_tag="KRH23_002953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HHS5226230.1"
                     /translation="MVKVLAFMGSPRKKGNVDTILDEIIKGVNDNNVEVKKYYLNDMN
                     IKGCQGCLYCRKVPTCAFKDDMIDIYEDIKSAEYIIIGSPVYICQVSAQTKLLLDRLY
                     PLTEIDKSKHIPRFGQKKLIMVYTQAAPISFLFKKYFKYTAKHLKGMGLNHYKTIVVT
                     KAFERNSTKKNFKVLKKAYKLGMKIAIDING"
     gene            complement(3500..4216)
                     /locus_tag="KRH23_002954"
     CDS             complement(3500..4216)
                     /locus_tag="KRH23_002954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HHS5226231.1"
                     /translation="MQQGSDYLKKFLEKHIDLLKKIPLFEGIKSDELEEMLECLGVVD
                     KTYPKDSIIFSVGSEVTSIGIMLKGSAHIIKEDIEGNRNIVAELLPGDLFGEVFACTR
                     LHKSNVTVTTTSSCEVLFIKFKSVTGICSSACVFHNRLVENMLQLIAEKNILLHNKIE
                     LLSRKTTREKLLMYFSKQIEQTGSHQFTIPFSRNEMADFLCVDRSSMSRELGKMRDEG
                     LLSFNKNKFEIFYFQNKLDI"
     gene            4381..5106
                     /locus_tag="KRH23_002955"
     CDS             4381..5106
                     /locus_tag="KRH23_002955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HHS5226232.1"
                     /translation="MMRKIIKIDEEKCNGCGLCVEACHEEAIGMVNGKAKLLRDDYCD
                     GLGDCLPTCPTNAISFEYREAAEYDEAAVKANMEAKKAQKKTLACGCPGSQSKSINRE
                     VSNSTSISNDIVEIKGSQLSQWPVQIKLVPTNASYLKNASLLIAADCTAYAYGNFHNK
                     FMKNKVTLIGCPKLDEVDYAEKLTEILKENDIKNIVVTRMEVPCCGGIVNAVKTALQN
                     SGKMIPWQIVTISVDGKIVDGEI"
     gene            5166..6758
                     /gene="hcp"
                     /locus_tag="KRH23_002956"
                     /gene_synonym="priS"
     CDS             5166..6758
                     /gene="hcp"
                     /locus_tag="KRH23_002956"
                     /gene_synonym="priS"
                     /EC_number="1.7.99.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016661 - oxidoreductase activity, acting
                     on other nitrogenous compounds as donors [Evidence IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxylamine reductase"
                     /protein_id="HHS5226233.1"
                     /translation="MEKMFCFQCEQTAGGKGCTINGVCGKKGGTANLQDELTGVLIGL
                     SRATIGNKNRPTSETDKIMIEGLFTTITNVSFDDEAIKRQIEKTEVEKSKLVPRCSDC
                     STTCNRNDNYDMKDLWNDNEDIRSLKSLILFGLRGMAAYAYHAMVLGYTDKDVNEFFY
                     EGLIAVGGDLSIDELLGLVMKTGEINLKCMELLDRANTETYGTPEPTQVSMKIEKGPF
                     IVVTGHDLYDLHKLLEQTKDKGINIYTHGELLPAHAYPKLKEYKHLKGNFGTAWQNQQ
                     KEFDNIPAPILFTTNCLMPVKDSYRDRVFTTEVVAYPGMVHIDEDKDFSSVIEKALEL
                     GGYREDVHMTGINGGDTLTTGFARGTVSSVQDKVVDAVKSGAIRHFLLVGGCDGAKPG
                     RNYYTEFVKQAPKDTVILTLACGKYRFNDLDLGDIGGLPRLMDMGQCNDAYSAIKVAV
                     SLANAFECGVNDLPLSMVLSWYEQKAVCILLTLLHLGIKNIYIGPSLPAFLSKNVLDI
                     LVDKFALTPISTPEEDMKKILG"
     gene            7129..8034
                     /locus_tag="KRH23_002957"
     CDS             7129..8034
                     /locus_tag="KRH23_002957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006629 - lipid metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HHS5226234.1"
                     /translation="MKNSNFNILAFDGGGLKGALSISILERIVKEYPNLLNNINMFGG
                     TSTGSLIALGLAYGVSPKEIKELYSIENSKYIFNKSYAEILRPKYENKNLKEVLLSIF
                     PEELELKDLNKLVMIPSFYIGNEENAWKPVFYNNMPNSFTKTSKVVDVAMASSAAPVF
                     FPTYNRHVDGGIIATDPSLACIIHAIDSGFKLKNTRLFSIGTGYVYNSIKADTTEWGA
                     IDWIINKEPDLPIISITLEGNSQMSQLFSQKLLGDNYYRLNPKMEKDVAMDDCDALEY
                     LMSLGENCDIKDAFGWIKKKSFYRN"
     gene            8158..9111
                     /gene="msrA"
                     /locus_tag="KRH23_002958"
     CDS             8158..9111
                     /gene="msrA"
                     /locus_tag="KRH23_002958"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008113 - peptide-methionine (S)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_function: GO:0033744 -
                     L-methionine:thioredoxin-disulfide S-oxidoreductase
                     activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HHS5226235.1"
                     /translation="MIKLATFAGGCFWCMVKPFDKYDGVIKVVSGYTGGHVENPTYQE
                     VCSGTTGHLEAIQITYDDDIISYDELLNIFWKQINPTDDGGQFGDRGTQYKTAIFYHD
                     EEQKNIALESREHLENSKIFDSKIVTDIIPATKFYEAEENHQDYYKKRPLNYNMYYKG
                     SGRYNFVKSHWDGNNINREELKKTLTPIQFEVTQNDMTEVPFENEYYDNNKEGIYVDI
                     VSGEVLFSSKDKFDSGCGWPSFSKPVIDKSIIERSDFSQGMYRVEVRSAKGNSHLGHV
                     FDDGPKELGGLRYCINSASLKFIPRENMEALGYGEYLKLFE"
     gene            9264..10394
                     /locus_tag="KRH23_002959"
     CDS             9264..10394
                     /locus_tag="KRH23_002959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HHS5226236.1"
                     /translation="MNLKDFNGKRLKSARIFRAKTIEQLSKETKINKKDLKAFEENKY
                     VPNIENTLKLSNILNFPKEYFYKNENINIVVEDSHFNPQSKLPRVEEISYREKIIIIH
                     KIYSFMENYIKFPKENLPNRKVMSDININDIESLAYKTREFWDLNSTPIVNMVSLLES
                     KGIIISGMNVDRKGATIFTQKQRISKESKYLISLGNDKKSASIRNYTLACELGYIISS
                     ELRIPSKQFSEDEYACAFLLPKESFLKDLTHPEDLDYYVELKKKWIVPISAMIFRAYN
                     LEKINYKKYNYLMNEMDKKGWLIEEPLDKMKGSSPTYLKRAVELLIENKIMSVNSIVS
                     SLEEFGINLYPEDLELLMGLKKGLLSQEVNKKSKVIKFDGKK"
     gene            complement(10511..11479)
                     /locus_tag="KRH23_002960"
     CDS             complement(10511..11479)
                     /locus_tag="KRH23_002960"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004459 - L-lactate dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HHS5226237.1"
                     /translation="MAIKPRKISIVGSGHVGSHCGFSLITQGVCDELFMIDIDESKSK
                     AQALDLADAVSYLPHKVHIEKGTFSDCKDSDIVVISVADSSEGPLRRQNTTRLDLLRP
                     TIGMIKSIVKPIVDSGFDGIFVVISNPVDVVTNYIWEKSGFPKNKVIGTGTALDSTRL
                     RRILSEETGIAQQSIQAYSMGEHGDSQMVPWSHVSIGGKPILDMIKDNPSTYSNLDLP
                     SIVEKNKKTGISIINGKDCTEFGIGTALVEIVKAILHNEKKVLPVSTLLEGQYNERNV
                     FAGVPCVIGKDGIEEIIEINMTEYEQNEFNKSCSVLREYIALSKTL"
     gene            11814..12002
                     /locus_tag="KRH23_002961"
     CDS             11814..12002
                     /locus_tag="KRH23_002961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226238.1"
                     /translation="MNYHTKEELVEALRVVSSSIINCGKGQKKFSVETSHHTRFKNII
                     EVMYISKSLIMDEISKRD"
     gene            12262..13461
                     /locus_tag="KRH23_002962"
     CDS             12262..13461
                     /locus_tag="KRH23_002962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DHHA1 domain-containing protein"
                     /protein_id="HHS5226239.1"
                     /translation="MEKLYYTNQYIRDFTAEIIEIKEVENKYHVLLDKTAFFPGGGGQ
                     FGDLGKIENDDVINVYEDGKKIYHVLDKKPIKIHKVKCSIDWDRREDGMHQHFGQHVL
                     SGCFFKTFNANTTGFHLGNEYSTVDIEGNLEEDKIREIELFANEIIRQNIQVETLLPT
                     KKELKKIWLRRDLPNTDEEIRVIKIGDLDTNACCGVHPKSTGELRMIKIKKWEKHKSS
                     TRIEFLAGKRAVDEVLKRDIYLTKICRYLSCSEEDAINGIVNLNSKVEEALIKKRRLE
                     EVVSTYQVKEMIEKANKVGNISVIKKIYDDEDLKYVNKIANKIAEYENSIALLAVKFN
                     DKINLVFACSKNLKDINMGVLLKDAISLIDGKGGGSKVLAQGGGKNNGNLEATLDYAF
                     MKIEKTL"
     gene            13513..14016
                     /locus_tag="KRH23_002963"
     CDS             13513..14016
                     /locus_tag="KRH23_002963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase family protein"
                     /protein_id="HHS5226240.1"
                     /translation="MEQQKDYIELYENEELIEIREARMDDLDTIAKFNYNLAKETEGK
                     ELDMDVLTKGVKALLLDERKGKYHVYTVFDKVVAQIMYTYEWSDWRNGNFLWIQSVYV
                     DKEYRRKGIFNYLFNYIKNICDKDENIVGMRLYVEKENINAKATYESLNMYECDYNMY
                     EYEVVHS"
     gene            14123..14440
                     /locus_tag="KRH23_002964"
     CDS             14123..14440
                     /locus_tag="KRH23_002964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226241.1"
                     /translation="MGVLKGMFYVFLFLDLVSIFCFFFNKGKIASNKIVFNAIGVLTF
                     VLCFMLFSYYPNNNLIGKFIASLFFIFGVAGVMLKEKNFLYARLLLTVVIVFSTLRLF
                     VIQ"
     gene            14598..15557
                     /locus_tag="KRH23_002965"
     CDS             14598..15557
                     /locus_tag="KRH23_002965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA];
                     GO_process: GO:0046677 - response to antibiotic [Evidence
                     IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HHS5226242.1"
                     /translation="MIESKKSEKLLLSIIYIIFLVYILMIIRIILFRDVPIYAIFKGT
                     FRNVNLIPFYTIYQFIVDSNLDFMKATVNIIENIGIFIPMGIFLPIVCKNLNKKTIII
                     VIILVSLAFELTQYIFALGSSDIDDVILNSLGGIIGINIYINMNKLFPNDINRFKAII
                     GTSLVLGVIGLGVISKNYHNLLTFKFRPDRKISKILIEENREIIKDINKDTVDIVGTF
                     ESFKKGIITIKAGSNNKVKRPENLIDSDGNIRIYLNENTKLVSYIITKESKMDIVKYE
                     EFDVKNLDLLRRYDTINVWIDKENQPKDKHGIMASKLLIGLYE"
     gene            15672..16457
                     /locus_tag="KRH23_002966"
     CDS             15672..16457
                     /locus_tag="KRH23_002966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative ABC transporter permease"
                     /protein_id="HHS5226243.1"
                     /translation="MEIIKYILYFFIYSFLGWTVESIGCSIASKRTINRGFLNGPICP
                     VYGFGAVIVISLLGRFNNVVIVFLLGMILTTILEYFTGFILETLFHAKWWDYSDRKFN
                     IKGRVCLKNAIYFGVMSVLIIRFIHPFIKYFVSIIPYRILISMAIITTLWTILDLIVT
                     IITLKKLDIKLNLLDDIITDLNDINVKLDEFDRGEIQALFKTINNDELEVREKINKIN
                     SKLDRIESNIILQKRVIKAFPHIKHKKQQEQLEHFKKIINEKR"
     gene            16749..18068
                     /locus_tag="KRH23_002967"
     CDS             16749..18068
                     /locus_tag="KRH23_002967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008483 - transaminase activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class III-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HHS5226244.1"
                     /translation="MSEITSQMISTEEKKYVAKTQKIPYYPVAFKSGDGAMLYDYEGN
                     EYVDFLASAGSANVGHGNKEISQAVKEQMDDITQYTLAYFHSDPPVKLAEKLVEIAPG
                     DNDKKVLYSATGSACIDAAIKLARGYTGRTKIISMCESYHGSTYGAISISALSTNMRR
                     KMGPLLPEVYHFHYPDKNRTAKECLDEIEYAFAHYLPAEEVAAIFIEPIAGDAGIIVP
                     PVEWVQGLSKICKENGILLVSDEIQQGMGRTGKWFGIENFGVEADLIVLGKSVGGGLP
                     LGAVVGRTEIMQSLDAPAHLFTLAGNTTVCVAALKSIEIIEKENLLQKSIEMGDYIKA
                     GFEKLKEKYDIIGEIRGIGLSIGVDIVKGKGSNEKHPDATAKICYRCIQTGLIMIFLG
                     QSTLRVQPPLVITKEQVDKAMNIIDSAIDDYLNGRIGDEVYEVTQGW"
     gene            complement(18143..18571)
                     /locus_tag="KRH23_002968"
     CDS             complement(18143..18571)
                     /locus_tag="KRH23_002968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226245.1"
                     /translation="MKDNNNTNKTIQFGEKKASLENNIQKNKNIKLDNTHKVIPYPKN
                     RKKDDKKKGNKKKNTNTSKVNKNNYGHSFFNNKYKYKRKPYVIALYTVILILLAILII
                     TKLTDSTNKGNYSRNTVSDTHKNDIRNIVFNESNNFLICG"
     gene            complement(18662..20038)
                     /gene="hydG"
                     /locus_tag="KRH23_002969"
     CDS             complement(18662..20038)
                     /gene="hydG"
                     /locus_tag="KRH23_002969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="[FeFe] hydrogenase H-cluster radical SAM
                     maturase HydG"
                     /protein_id="HHS5226246.1"
                     /translation="MFINHELINSLLEDAKNSTSDDIEKVLDKADRREKLSYKDIATL
                     LEVEDKKQLDRLFSIAGQIKNEIYGNRVVLFAPLYVSNYCVNECVYCGFSKCNKFKRK
                     KLTMEEIKEEVKILEKMGHKRLALEAGEDPKNCDINYILDCLDAIYSTYNENGNIRRV
                     NVNIAATSVDEYKLLKEKGIGTYILFQETYHKPTFIKMHGQSIKNDYYYHLTAFDRAM
                     EAGVDDVGAGVLFGLSDPKFEVLGLMMHNEHLEEKFGVGFHTISFPRLKKAEGMSLED
                     FPHLVSDDMFKKIVAITRLAVPFTGIIMSTRETAEMRNELLKYGVSQISAGSLTGVGG
                     YKAYEDGDNTEQFEVGDHRSPVEVLKELITDGYIPSYCTACYRKGRTGDRFMSLAKSR
                     QIHNVCTPNALTTLNEFLIDYGDEELKIMGKKLIAEEIGKIEREDIRNIVSNNMTALE
                     RGERDLYL"
     gene            complement(20039..21124)
                     /gene="hydE"
                     /locus_tag="KRH23_002970"
     CDS             complement(20039..21124)
                     /gene="hydE"
                     /locus_tag="KRH23_002970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="[FeFe] hydrogenase H-cluster radical SAM
                     maturase HydE"
                     /protein_id="HHS5226247.1"
                     /translation="MTKNKIKYFIDKLYSINSLSFDELLYLIENIDNEEYNFEQNLRN
                     YLYKQASDMRNKHYGNRVYLRGLIELTNYCKNNCYYCGIQSSNKNIIRYRLSLDEILE
                     CCDIGYKIGYRTFVLQGGEDAYFTDDKICEIVSSIKNKYEDCAITLSLGEKSYDSYKK
                     YFLCGADRYLLRHETATDSHYKKLHPPNIELRTRKECLKNLKEIGYQVGAGFMVESPF
                     QNNEDLVRDLLYLKELNPHMVGIGPFIPHHDTIFKDYKHGDLEKTLLMLSITRLLLPK
                     VLLPATTALASINPSGRNAGLLAGCNVIMPNLSPQEFRKQYSLYDNKAFTGQEACEYH
                     QSLEENIKSLGLEVDYSRGDNIEWRRL"
     gene            complement(21160..22368)
                     /gene="hydF"
                     /locus_tag="KRH23_002971"
     CDS             complement(21160..22368)
                     /gene="hydF"
                     /locus_tag="KRH23_002971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="[FeFe] hydrogenase H-cluster maturation GTPase
                     HydF"
                     /protein_id="HHS5226248.1"
                     /translation="MSLNSTPQSVRVHIGLFGKRNAGKSSIINAITNQSAAIVSDIAG
                     TTTDPVFRPMEILPIGPCVLIDTAGLDDVGELGELRIGKSLDVLEKTDIALLVVDCQI
                     GISQEDLSLIEKFNDKNIPHILILNKIDTIKNQSEILNLTKNKVKCPVVSVSSTDKIG
                     IENLKNEIIKVLPKDSTEFKLVSDLIEPNDLVVLVVPIDKAAPKGRLILPQQQVIRDI
                     LDNGAISIVTKEDSLKETLSNLGKKPKLVITDSQVFPQVDKDTPKDIPLTSFSILFAR
                     QKGDLKELINGAYALENLKDGDKILMAEGCTHHRQTDDIGTVKIPNMIRKKTGKNITF
                     EFSSGVSFTEDINKYALVVHCGACMMNRAGMLSRIEKAKSFNVPIVNYGVLIAYVKGI
                     LERSLELFNY"
     gene            complement(22383..22634)
                     /locus_tag="KRH23_002972"
     CDS             complement(22383..22634)
                     /locus_tag="KRH23_002972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_process: GO:0065007 - biological regulation [Evidence
                     IEA];
                     GO_process: GO:0065009 - regulation of molecular function
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TM1266 family iron-only hydrogenase system
                     putative regulator"
                     /protein_id="HHS5226249.1"
                     /translation="MKKVAVISAILEEPKECQFKFNEVVSGFKGIIKGRMGIPCEEEG
                     VSIVCIAVVGEMDTINSLTGKLGNIPHVSVKTSISKKEV"
     gene            complement(23015..24055)
                     /locus_tag="KRH23_002973"
     CDS             complement(23015..24055)
                     /locus_tag="KRH23_002973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HHS5226250.1"
                     /translation="MNLNLTNTINLMKKYLDIPSPAGYTENAVLEIKKDFENLGLDTI
                     LTKKGALIATLPGEDDSNQITISAHMDTLGAIVKEISSDGTLKYHKVGGGCWAAIEGE
                     NCTVITRKGKKIRGSVVFKYASTHIYGQTKAATERNEETMIIRLDEKVFTKQDVLDLG
                     ISVGDFVCLDHRFEATESGFIKSRYIDNKSAVAMVLEICRYFKENNLTPKHTTNFYIS
                     NYEEIGHGVSKCLPEKTKEFVAIDIAPTGPSQTSSEHGVTIVAKDNLSLYDFNLRNKL
                     VDVAEDNNLDYAVDVFTFYGSDASEAIRWGEDVQIACVGPGTNNSHHYERTHIEAIEN
                     TLKLLINYMLKE"
BASE COUNT         9153 a         2856 c         3906 g         8245 t
ORIGIN      
        1 tgaataaaaa gaatgtataa taagtataat aatttgtatt tattattggg aaaggaaaat
       61 gttaatatgg atagttatag acaacttaaa gctaaaatac catgtaagga aacaggtata
      121 gaaataaaga ggactttatg tgatatttgt tctccaggag tacattgtgg aattgatgca
      181 tatgttaaag atggtaaagt aataaaaata gaaggtacaa aagaacatcc aatgaataaa
      241 gggttgttat gtaccaaagg tctttgcaat agagaatata tctatagaga agatagaata
      301 aaaacacctc taaaaagaat tggaaaaaga ggtgaaggaa aatttaaacc aatatcatgg
      361 gatgaagctt atagagaaat agcagaaaaa ttaaatagag taaaatctga gtatggagca
      421 aagcatgtag ctttttttac gggttatgga aagtggtata gacctttttt acaaaggttt
      481 gcatcttcat ttggttcacc taattatggt acagaatcta gttcatgttc aacatcagca
      541 cagatggctg gaaatgttgc tactggaaga aactttacaa tgcaagatat ggagaatgca
      601 aaaacttatt tagggtgggg atttaatcca tactactcta aatttttaaa tagtgtgaat
      661 ctaataaaat taaaagaaaa aggtctaaaa tttataattg tagaccctag aataacaccg
      721 acaactcaaa aactagcaga tttacattta agaattaaac ctggaactga tggagcttta
      781 gctcttggaa tggcgaatct atttatacaa aaggatttaa tagatagaga atacatagaa
      841 aagcatgtac atggatttaa tgaatataaa gaatatgtaa aattatttga tttagatact
      901 gtaagtagaa ttacaggagt ttctaaagat aatatagtaa aagctgttga gatgttgtca
      961 caaggtccat tttgtataaa tgaaagtgca gctccaatag ttcaccatca aaatggattt
     1021 caaaattata gagcaatgat gtctttatcc gctataacag gtaattatga tagaataggt
     1081 ggaaacatac caaaacaaga ttactttgct ggtaagatag gtggattcca aacactagaa
     1141 aaagagtttg taaaagaagt tctacctaaa aatataaatg aaagaattgg tggagaaaga
     1201 tttcctctat ggaatgaaat ggtgactcaa tttcaagcta tggatttacc taggcaaata
     1261 gaagaaaaga caccatatga aataagagct ttgttttgtc atgggataaa tgctagaatg
     1321 tttcctaatt cagggagact ttttaaagcg ttgaatagtg tagatttttt tgtgaatata
     1381 gatttattta tgacagatac atcaaaatat gcagatatac ttttacctgc atgtacatca
     1441 tttgagagag aagaatgtaa gagttatcca ggagggtata ttacatatac caaaaaagtt
     1501 attgataaat tatacgattc aaaatcagat gtagaaatac tttcagattt agcaaatgct
     1561 atgaatatag atgatgattt attaaaagca ggttatgaag caagtataag acatatgttt
     1621 aaaaatacat gtgtagatgt agataaactt aaagaaagtg atttaccatt aaaatgtaaa
     1681 gattttaagc catatatagt aggttcatat acaagagaag ggtatgatac tagcacttct
     1741 aggtttgaat taaaatctac aattattgaa aaatataaag attttgggct ggacgcacta
     1801 ccaacatata gaggatttaa tgataatata gatgatgaat atactcattt attgacatca
     1861 ggagcaagaa tttcaaatgc actacattca agacttcatg acatcaaact ttcaagaata
     1921 ttaaaaaatg aagctagttg tgatatttct agcttagatg caaaagaatt gggtgttatc
     1981 agtggagatt atataaaaat aactactaag ataggaagtt tggatgtaaa agtcaatgtt
     2041 actgatagag tcttatataa gaatatacat atgtatcatg gatatagaga agctgatata
     2101 aatagtatta tttgtgataa ttttgaccct tatagtggat tccctgcgta tagaagttgt
     2161 aagtgtaaga ttgaaaaaat gaatagataa atggagagat ataatgaaaa gtttatttaa
     2221 atttaataaa gaattatgta cagcatgtgg agcatgtttg cttgcatgta tagaccaaaa
     2281 tgataataat atagacaatg gtgaactttt tagacatgta tttacaatag aggaaggtga
     2341 aaatatagaa tatttttcat tagcatgtat acattgtaat gagccaaaat gtttaggtgt
     2401 atgtcctaaa aattgtttta aaagagaaga aggattcatt gtattagaca atcaaaactg
     2461 tatagggtgt aaactttgtg aaaaagcttg tgaatatgga gccttaattt atggaaatga
     2521 tggtaaggca aataagtgta atggttgtat tgagagatat aagtgtggta tggattcacc
     2581 ttgtgtaatg gtatgcccta caggagcatt aaaatttaat aaataattgt attaaattgc
     2641 tatactactt ttaaataatt gtgttaagaa ttattttttg ctatactttt gtaatataaa
     2701 atgtaaataa aacaaataca aagtatataa aatatatttt tagaataaag tgtgctttag
     2761 attaaattta gaaaaataaa ttagacagga gaacttaata tggtaaaagt attagccttt
     2821 atgggcagtc caagaaaaaa agggaatgta gacacaatac ttgatgagat aataaaaggt
     2881 gtaaatgata ataatgttga agttaaaaaa tattatctaa atgatatgaa tattaaagga
     2941 tgtcaaggct gtctatactg tagaaaagtt cctacttgtg catttaaaga cgatatgatt
     3001 gacatatatg aagatataaa aagtgctgaa tatataataa ttggttcgcc agtatatata
     3061 tgtcaggtat cagctcaaac aaagctactt ttagatagat tgtatccttt aacagagata
     3121 gataagtcta aacatatacc taggtttggt caaaaaaagt taatcatggt ctatactcaa
     3181 gcagctccta tttcgttttt atttaaaaaa tattttaagt atactgcaaa acatttaaag
     3241 ggcatgggat taaatcacta caaaactata gttgtaacca aagcatttga aagaaattcc
     3301 actaaaaaaa attttaaggt attgaaaaaa gcctataaac ttggaatgaa aatagccatt
     3361 gatatcaatg gatagataaa agtttaattt atagtatagc taaaggagca ttaattatta
     3421 atactccttt tttgtataaa ggtttctaga aaataactaa taaaaaacaa tattatttga
     3481 atacagatat tatacaagcc tagatatcta acttgttttg aaaataaaag atttcaaatt
     3541 tatttttgtt aaaagataac aagccttcat ctcgcatctt gccaagctct cttgacatag
     3601 aacttctgtc aacacataaa aaatcagcca tttcatttct tgaaaaggga attgtaaact
     3661 ggtggctacc tgtttgttct atctgttttg aaaaatacat aagcaatttc tcgcgagttg
     3721 ttttacgaga aagtaattct attttattgt gaagtaaaat gtttttttca gctattaatt
     3781 gtagcatatt ttcaacaagc ctattatgaa atacacatgc agatgaacaa ataccagtta
     3841 cacttttaaa ctttataaat aaaacttcgc aagaagatgt tgtagttact gtaacattac
     3901 ttttatgtag tctagtacat gcgaatacct ctccaaataa atctccaggc aagagttcag
     3961 ctacaatatt cctattccct tcgatatctt cctttattat atgagcactt cctttaagca
     4021 taattccaat agaagtaact tcacttccaa cagagaatat tatactatct tttgggtaag
     4081 ttttatctac aacacctaaa cattccaaca tttcttcaag ttcatcactt ttaattcctt
     4141 caaatagagg aattttttta agtaggtcta tatgcttttc taaaaatttt ttcaaataat
     4201 cacttccttg ttgcatatgc aaccgataat ttgttttcat tgtactatac taagtttata
     4261 aaagcaaggg gatataaaaa tcctactaca agaaatttga aataaagaaa tataggtatt
     4321 aaaaataaat atataagaaa tcaatacttt aaattaaaaa aattttatga ggtgatataa
     4381 atgatgagaa aaataattaa aattgatgag gaaaagtgta atggttgtgg actatgtgtt
     4441 gaagcttgtc atgaagaagc tataggaatg gtaaatggaa aagcaaaact tttaagagat
     4501 gactattgtg atgggctggg agattgtctg ccaacttgtc caacaaatgc gatttcattt
     4561 gagtatagag aagcagcaga atatgatgaa gctgcagtaa aagcaaatat ggaagcaaag
     4621 aaagcacaaa agaaaacttt agcatgtgga tgtccaggtt ctcagtctaa gtcaataaat
     4681 agagaggttt caaatagtac gtctataagc aatgatatag tagagataaa aggttctcaa
     4741 cttagtcaat ggccagtaca aataaaatta gtaccaacta atgcatcata tttaaagaat
     4801 gcaagtcttt taatagcagc agactgtaca gcgtatgcat atggaaattt tcataataaa
     4861 tttatgaaaa ataaggttac attaatcgga tgccctaaac ttgatgaagt tgactatgct
     4921 gaaaaactta cagagatttt aaaagaaaat gatattaaaa atatagtagt aacacgtatg
     4981 gaagttcctt gctgtggtgg tatagtaaat gctgttaaga cagctctaca aaatagtgga
     5041 aaaatgatac catggcaaat agttactata tctgtagatg gaaaaattgt agatggagaa
     5101 atttaattaa gtgaattata gaaaaatata ataaatttta ataaataaaa agggaggaat
     5161 aaaaaatgga aaaaatgttt tgttttcaat gtgaacaaac agcaggaggt aaaggttgta
     5221 ctataaatgg tgtatgtggt aaaaaggggg gtacagctaa cttacaagac gaacttacag
     5281 gagtgttgat tggtctttca agagcaacta ttggaaataa gaatagacca acaagtgaaa
     5341 cagataaaat tatgatagag gggctattca ctactataac gaatgtaagt tttgatgatg
     5401 aagctataaa aagacaaatt gaaaaaactg aggtagaaaa aagtaagctt gtacctagat
     5461 gttcagattg ttcaacaact tgtaatagaa atgataacta tgatatgaag gatttatgga
     5521 atgataatga ggacatacgt tcattaaaat cattaatctt atttggatta agaggtatgg
     5581 ctgcctatgc atatcatgca atggtacttg gttatacaga caaagacgta aatgaatttt
     5641 tctatgaagg attaatagca gttggaggag acttgtctat tgacgaactt ttaggtctag
     5701 ttatgaaaac tggagaaata aacttaaaat gtatggaatt gcttgataga gcaaatactg
     5761 aaacttatgg aacaccagaa cctacacagg tatctatgaa aatcgagaaa gggccattta
     5821 ttgtagttac aggacatgac ctttatgatt tacacaaatt attagaacaa acgaaagata
     5881 agggtataaa tatatatact catggtgagt tattaccagc acatgcatat ccaaaactaa
     5941 aagaatataa acatctaaaa ggtaattttg gtacagcatg gcaaaaccag caaaaagaat
     6001 ttgataatat tcctgctcca atattattta caacaaactg tttaatgcct gttaaagata
     6061 gttatagaga tagagtattt actacagaag tagttgctta tccaggtatg gttcatattg
     6121 atgaagataa agatttttct agtgtaatag aaaaagctct tgaacttgga ggatatagag
     6181 aagatgttca tatgactggt attaatggag gagatacatt aactactggt tttgcaagag
     6241 gtacagtttc atctgtacaa gataaagtag tagatgctgt aaagagtgga gctataagac
     6301 actttttatt ggttggaggt tgtgatggtg caaaacctgg aagaaattat tacactgaat
     6361 ttgtaaaaca agctcctaaa gacactgtta tattgacact tgcatgtgga aaatatagat
     6421 ttaatgattt agaccttggg gatataggtg gcttacctcg tttaatggat atgggacaat
     6481 gtaatgatgc ttatagtgca attaaagtgg cagtttcatt ggcaaatgct tttgaatgtg
     6541 gagtaaatga tttgcctctt agcatggtac tgtcatggta tgagcagaaa gctgtttgta
     6601 tacttcttac actacttcat ttaggtatca aaaatatcta tataggacct tctttaccag
     6661 cattcttatc taagaatgta ttagatatat tggttgataa atttgcattg acacctatat
     6721 ctactcctga agaagatatg aagaagattt taggataaat aaatatatct atacttaaag
     6781 atatttatag ttaaaatatt tttaagtatg ccacaattaa gataaggggt taaacttaaa
     6841 atttgattaa aaaatcaatt ttgagatgac cctttattta ttttttgtaa taattgaaaa
     6901 ataaacctgc tttcagtata ttcttttaag aatttttgta ttaaatttat aatacttaga
     6961 tatataatat cttatatatt ttattttaag tattaaaggt ttgaatgtaa cttaaatatt
     7021 aaaagaggaa cattgtaata tgtaacttgc ataaaatata tatactatag tgaaattatt
     7081 ttgattaaaa tttaaaatat aaggtgtttt atgtgggggt atatgtatat gaaaaattct
     7141 aattttaata tattggcatt tgatggtggt ggattaaaag gggcattgag tatatccata
     7201 cttgagagga tagtaaaaga gtatccaaat ctattaaaca atataaatat gtttggaggt
     7261 acatctacag ggagtctaat tgcactaggg cttgcgtatg gtgtaagccc taaagagata
     7321 aaagaacttt actcaattga aaattcaaag tatattttta ataaaagtta tgcagaaata
     7381 ctcagaccaa agtatgaaaa caaaaactta aaagaagttt tattaagtat atttccagag
     7441 gaactagaat taaaagattt aaataaatta gtaatgatac caagttttta tataggaaat
     7501 gaggaaaatg catggaaacc agtgttttat aacaatatgc caaattcttt tacaaagacc
     7561 agcaaagttg tagatgtagc aatggcaagt agtgctgctc cggtattttt tccaacatat
     7621 aatcgtcatg ttgatggagg aataatagca actgacccga gtttagcgtg tataatccat
     7681 gccattgaca gtggatttaa acttaagaat acaagacttt tttcaatagg gactggatat
     7741 gtatataaca gtataaaggc agatactact gaatggggag ctattgactg gataattaat
     7801 aaagaacccg atttaccaat tatatctatt accttagaag gaaattctca aatgagtcag
     7861 ttattttctc aaaaacttct tggagataat tactatagat taaatcctaa gatggaaaaa
     7921 gatgtagcta tggatgattg tgatgcatta gaatatctaa tgtctttagg agaaaattgt
     7981 gatataaaag atgcttttgg atggataaag aaaaagagct tttatagaaa ttagattcaa
     8041 tttgcaattg tatttttaca catgatttca ttgagtaggt aaaaataata aaatgcagat
     8101 tattaagtta cttcttaggg aataaataaa gtataattta tttaaggagt gatgaaaatg
     8161 ataaaacttg ctacttttgc aggtggatgt ttttggtgta tggtaaaacc ttttgataag
     8221 tatgatggag ttattaaagt agtttctgga tatacaggtg gtcatgttga aaaccctaca
     8281 tatcaagagg tatgctcagg aactactggt catttagaag caattcaaat aacatatgat
     8341 gatgatataa taagttatga tgaacttcta aatatcttct ggaaacagat taatcctaca
     8401 gatgatggtg gacaatttgg tgatagggga actcaatata agactgctat attttatcat
     8461 gatgaagaac aaaaaaatat agctttagag tcaagagaac atctggaaaa tagtaaaata
     8521 tttgatagta aaatagtgac tgatataatt ccagcaacta aattctacga agcagaagaa
     8581 aatcatcagg attattataa gaaaagacca ttaaactaca atatgtatta taaagggtct
     8641 ggaagatata attttgtaaa aagccattgg gatggaaaca atataaatag ggaagagtta
     8701 aaaaagactt taactcctat acaatttgaa gtcactcaaa atgatatgac agaagtacct
     8761 tttgaaaatg aatattatga caataacaaa gagggaattt atgttgatat tgtaagtgga
     8821 gaagtgttat tttcttcaaa agataaattt gattctggat gtgggtggcc aagtttttca
     8881 aagccagtta tagataaatc tatcattgag agaagtgatt tctcacaagg tatgtacaga
     8941 gttgaagtaa gaagtgctaa aggaaattct catttaggcc atgtatttga tgatggtcca
     9001 aaagaacttg gaggtttaag atattgtata aattctgctt ctcttaaatt tataccaaga
     9061 gaaaatatgg aagctttagg atatggagaa tatttaaaac tttttgagta attaggaata
     9121 tttattataa acttatctaa aaggtgaaaa tataaaaaaa tattttcacc ttttgttttt
     9181 ttgtcaatag tatgataaat tattaattgt aatcttattt ataccaatag attaagaatt
     9241 taattttgaa agagagaaaa caaatgaatt taaaagactt taatggaaag agattaaaat
     9301 cagctagaat ttttagagca aagacgatag aacagttgtc taaagaaact aaaataaata
     9361 aaaaagattt aaaagctttt gaggaaaata agtatgtacc aaatatagaa aatacattaa
     9421 aattatctaa tatattaaat tttccaaaag agtattttta taaaaatgaa aatataaata
     9481 tcgttgtaga ggatagccac tttaaccctc aatctaaact acctagagta gaagagattt
     9541 cttatagaga aaaaataatt ataatacata aaatatattc atttatggag aattatatta
     9601 agtttccaaa agaaaacttg ccaaatagaa aagtaatgtc agatattaat ataaatgata
     9661 tagaatctct tgcatataag actagagagt tttgggattt aaatagtact ccaatagtaa
     9721 atatggtaag tttgttagag tctaaaggga ttataatatc aggtatgaat gtagatagaa
     9781 aaggggcaac tatctttact caaaaacaga gaattagtaa agaatctaaa tatctaatat
     9841 ctctgggtaa tgacaaaaag tcagcatcaa ttagaaatta tactttggca tgtgagcttg
     9901 gatatataat atcaagtgaa ttaagaatac caagtaagca attttcagaa gatgagtatg
     9961 cctgtgcatt tttattgcca aaagagagtt ttttaaaaga tttgactcat ccagaagatt
    10021 tagattatta tgtagaacta aagaaaaaat ggattgtacc tatatctgct atgattttta
    10081 gagcatataa tctagaaaag ataaattaca aaaaatacaa ttatcttatg aatgaaatgg
    10141 ataaaaaagg ctggttgata gaagaaccac tagacaaaat gaaaggttca agcccaacgt
    10201 atttaaaaag agcagttgaa ttattgatag aaaataaaat aatgagtgta aatagtatag
    10261 tatcaagttt agaggaattt ggaataaatc tttatccaga agacttagaa ttattgatgg
    10321 gattgaaaaa aggattgtta tctcaagagg taaataaaaa aagtaaagtt ataaaatttg
    10381 atggtaaaaa ataggtttat attttagtat taaaattaaa agcaggtaca aatgatttaa
    10441 acattaactt agttaaaagt cttttcaata agtcatttac ctgcttttag tgtaagaaag
    10501 aatattgaat ctaaagtgtt tttgaaagtg caatatattc ccttaaaaca gaacaagatt
    10561 tattaaattc gttttgctca tattcagtca tattgatttc aataatttct tcaataccat
    10621 cttttcctat aacacatgga acacctgcaa atacatttct ttcgttatat tgaccttcta
    10681 gtaatgtaga aactggaaga acttttttct cattgtgtag tatagctttt acaatttcta
    10741 ctaaagcagt acctatacca aattctgtac aatctttacc atttattata cttatccctg
    10801 tttttttatt tttttcaact attgatggta agtctaaatt gctataagta cttgggttgt
    10861 cttttatcat gtctaagatt ggtttaccac caattgaaac atgagaccaa ggaaccattt
    10921 gagaatctcc atgttcaccc atagaataag cttgaattga ttgttgagcg attccagttt
    10981 cttcagataa aatccttcta agtcttgttg aatctaaagc tgttccagtt ccaatgactt
    11041 tgtttttagg aaagccagat ttttcccaaa tataatttgt aactacatca acaggattag
    11101 atatgactac aaatatacca tcaaagccag aatcaactat gggttttact atagatttta
    11161 tcattccaat agttggtctt agtaagtcta atctagttgt gttttgtcta cgtaaaggcc
    11221 cttctgaaga gtctgcaaca cttatcacta ctatgtcaga atctttacag tcagaaaaag
    11281 ttcctttttc tatatgtact ttatgtggca gatatgaaac tgcatcagct aaatctaaag
    11341 cttgagcttt tgatttagat tcatctatat caatcataaa gagttcatca caaactcctt
    11401 gagttattaa actaaatcca caatgagaac caacatgccc tgaacctaca atagatattt
    11461 ttcttggctt tattgccatt ttaaatcact ccccctaaaa taacgataca ttgaaaatta
    11521 tagatgttat taaaagctgt ttttggatat tttaatattc tattatttca gaaaatttat
    11581 ttaatatgat tttatactaa aatttttaaa aaagcaatgt taatatactc tctattagtg
    11641 aatattaaag tattatatgt atattaataa ttattaaaat atttaatgtc actgatagtt
    11701 agaatattta agtgctaaaa gatgtgtata aataataatg atgtcagttt ataatgatat
    11761 taaattgaga tatgctgttt ctctaaatta aaaaataaag gagtaaatgt gttatgaatt
    11821 atcatacaaa agaagaattg gtggaagcac tgagagtagt atcttcaagt attattaatt
    11881 gtggaaaagg acagaagaaa ttttctgtgg agacatctca tcatacacgt tttaagaata
    11941 ttatagaagt aatgtatatt tcaaaatcat taataatgga tgaaattagt aaaagagatt
    12001 gaagcttatt ttgcaattta acatgtttta atatacattt tattatataa gaaaataagt
    12061 aaacatacat gttataaaat attgaaataa tatacaatta taaatttgtt aacattaata
    12121 tctatatgtt aaaatatagt agaagatgtt agtaaataat aggatgagtt ctattttaat
    12181 acaattaaat taagcttagt ttgaaatttg tatctaaaaa gtaaagtaat ctagaattaa
    12241 gaaaatggag atagaattat aatggaaaaa ttatattata caaatcagta tataagagat
    12301 tttacagcag aaataattga aataaaagaa gtagaaaata agtatcatgt tttattagat
    12361 aagacagctt tttttcctgg tggaggaggt cagtttggag acctgggaaa aatagagaat
    12421 gatgatgtaa taaatgtgta tgaagatgga aaaaaaatat accatgtatt agataaaaaa
    12481 cctataaaga tacataaggt aaagtgtagt attgattggg atagaagaga agatggaatg
    12541 catcaacatt ttggacaaca tgtattgtct ggatgttttt ttaaaacttt taatgcaaat
    12601 acgacaggtt ttcatttggg aaatgagtat agtacagtag atatagaagg taatttagaa
    12661 gaggataaaa ttagagagat agagttgttt gccaatgaaa ttattcgtca aaatatacaa
    12721 gtagagacat tacttccaac gaaaaaagaa ctaaaaaaga tttggttaag acgtgatttg
    12781 ccaaatactg atgaagagat aagagtaata aaaataggtg atttagatac gaatgcatgt
    12841 tgtggagtgc atccaaaatc aactggtgaa ttgagaatga taaaaataaa gaaatgggaa
    12901 aaacataagt caagtacaag aatagagttt ctagcaggta aaagggcagt ggatgaagta
    12961 ttgaagaggg atatatattt gactaaaata tgtagatatt taagctgtag tgaggaagat
    13021 gctataaatg gtattgtaaa tctaaatagt aaagtggaag aggctttaat taaaaaaaga
    13081 aggcttgaag aagtagtatc tacatatcag gtcaaagaaa tgattgaaaa agcaaataag
    13141 gttggcaata tttcggtcat taaaaaaatt tatgatgatg aagatttgaa atatgtaaat
    13201 aagatagcaa ataaaattgc agaatatgaa aatagtattg cattattagc tgttaaattt
    13261 aatgataaaa taaatttagt ttttgcatgt tctaaaaatt taaaagatat taatatggga
    13321 gttttattaa aggatgcaat aagtcttata gatggcaagg gtggtggaag taaagtatta
    13381 gctcaaggag gaggtaagaa taatggaaat ttagaggcta cacttgatta tgcatttatg
    13441 aagatagaaa aaactctata aatatattat ataaaaaacc ttagtagata aaatagatat
    13501 ggaggaataa gtatggagca acaaaaggac tacatagagt tatatgaaaa tgaagaacta
    13561 atagagataa gagaagcacg tatggatgat ttggatacaa tagcaaaatt taattataat
    13621 ttggctaaag aaactgaagg aaaagaactt gatatggatg ttttaactaa aggtgtaaaa
    13681 gcattgttat tagatgagag aaaaggaaaa tatcatgtat atacagtatt tgataaagtt
    13741 gttgcacaga ttatgtatac atatgagtgg agtgattgga gaaatggaaa tttcctttgg
    13801 attcagagtg tatatgtaga taaggaatat agaagaaaag gtatctttaa ttatttattt
    13861 aattatataa aaaatatatg tgataaagat gaaaatatag ttggaatgag attatatgta
    13921 gaaaaagaaa acataaatgc aaaagcaaca tatgagtctt taaatatgta tgagtgtgat
    13981 tataatatgt atgaatacga agtagtacat tcgtaatata aatttgtaat actgttatac
    14041 ttatgttata aagtattgat tatattgacg attatatgaa ataaactgga tattataatt
    14101 agaattttta gggggtataa aaatgggcgt tttaaaagga atgttttatg tatttttatt
    14161 tttagattta gtgtcaatat tctgtttctt tttcaataaa ggaaaaatag catctaataa
    14221 aattgtgttt aatgcaatag gagtacttac atttgtactt tgttttatgc tttttagtta
    14281 ttatcccaat aataatctta ttggaaaatt tattgcttct ctatttttta tatttggagt
    14341 tgcaggagtt atgttgaaag aaaaaaattt tttatatgct agacttcttt taactgtagt
    14401 tatagttttt tctacattaa gattgttcgt tattcaataa aatgtatttg tatgaaaatt
    14461 tattaaagtc tacacattta agtgtaggct tttttgattt tttgtttgaa aattaaggaa
    14521 attttaagga aattttaaaa tcgtcttaaa tatttattga tatacttaaa atattaatag
    14581 cgaaaggaga cttatcagtg atagaaagta aaaagtcaga aaaattgtta ctgtcaatta
    14641 tatacataat atttttggta tatattttaa tgattataag aataatttta tttagagatg
    14701 taccaattta cgctattttc aagggaacgt ttaggaatgt aaatttaatt ccattttata
    14761 caatatatca atttatagta gatagtaatc ttgactttat gaaagctact gtaaatatta
    14821 tagaaaatat aggtatattt attcctatgg gaattttttt acctatagta tgtaaaaatc
    14881 taaataaaaa aactataatt atagtaatta tacttgttag cctagcattt gaattaacac
    14941 aatatatttt tgctcttgga agtagtgata tagatgatgt tattttaaat tcattaggtg
    15001 gcataattgg aattaatatt tacataaaca tgaataaatt atttcccaat gatattaaca
    15061 gatttaaggc tataataggt actagtttag ttttaggagt tataggatta ggagttattt
    15121 ctaaaaatta tcataactta ctaactttta aatttagacc tgatagaaaa atatcaaaaa
    15181 tattaattga agaaaatagg gaaataatta aagatataaa taaagataca gtagatatag
    15241 ttgggacatt tgagagcttt aaaaaaggaa taataactat taaagcaggt tctaataaca
    15301 aagtaaagag accagagaat ttaattgatt ctgatggaaa tataagaatt tatttaaatg
    15361 aaaatacaaa attagtatct tatataatta ccaaagaatc aaaaatggat atagttaaat
    15421 atgaggaatt tgatgtgaag aatttagatt tattaaggag atatgatact attaatgttt
    15481 ggattgataa agaaaatcag ccaaaggata aacatggtat tatggctagt aaattattaa
    15541 ttggattgta tgaataaaat attaaacaag aataaaagaa taacaaatat aaaaaacgaa
    15601 aaaactattt ctataattat ttttacgttg tgcataaaat aagaacatta gtgaaggagt
    15661 agagataaat tatggagata ataaaatata tcttgtactt ttttatatat tcatttttag
    15721 gatggacagt agaaagtata ggatgttcta tagcaagcaa aagaacaatc aacagaggtt
    15781 ttttaaatgg tccaatatgc cctgtttatg gttttggagc ggtaattgtg atatcactat
    15841 tgggaagatt taataatgta gtaatagtat ttctattagg aatgatttta actacgatac
    15901 tagaatattt tacaggattt attttagaaa ctttatttca tgctaaatgg tgggattatt
    15961 ctgacagaaa attcaatata aagggtagag tatgtttaaa aaatgcaata tactttggtg
    16021 taatgtctgt tttaataata agatttatac atccatttat aaaatatttt gtaagtataa
    16081 ttccatatag aatattaatt tcaatggcta taattacaac actttggact atacttgatt
    16141 tgattgttac tattataaca cttaaaaaat tagatataaa gttaaactta ctagacgata
    16201 taattacaga ccttaatgat ataaatgtga aattggatga atttgataga ggagaaatac
    16261 aagctttatt taaaacaata aataacgacg aattagaagt tagagaaaaa ataaacaaaa
    16321 taaatagtaa gttggaccgt atagagtcta atattatttt acaaaaaaga gttataaaag
    16381 cttttccaca tataaaacat aaaaaacaac aagagcaact agaacatttt aaaaaaatta
    16441 ttaatgagaa aaggtaatta tacaatttaa tgaagacgaa tagaataatg gtatttataa
    16501 gatgattttc agaggactct ataaaaatag aatagagtcc tttatttttt gaaaaataat
    16561 gtttatttga taaaaataaa atatattgtt tctgaataac aaatattttg aaaattataa
    16621 aaacatatat tgacaatttg tgtcaaaaat actaacatta agtatataaa gaattttata
    16681 tgagaatatc tttataaatc gcaataattt taaaacataa atttatttaa agaggggatg
    16741 atttgccaat gagcgagata actagtcaaa tgataagtac agaagaaaaa aaatatgttg
    16801 ctaaaactca aaagatacct tattatccag tagcatttaa atcaggtgat ggtgcaatgc
    16861 tatatgatta tgaaggtaat gaatatgtag attttttagc aagtgcaggc tctgcaaatg
    16921 taggtcatgg taataaggaa atctcacaag cagttaaaga acaaatggat gatataacac
    16981 aatatacact tgcatatttc catagtgatc ctcctgtaaa attagctgag aagcttgtgg
    17041 aaatagcccc tggagataat gataaaaaag tactatacag tgcaactggt tctgcttgta
    17101 tagatgctgc tataaaatta gcaagagggt atactggaag aacaaagata atatctatgt
    17161 gtgaatctta tcatggaagt acttatggag ctatatctat atctgcttta agtacaaata
    17221 tgagaagaaa aatgggtcca ttgttaccag aagtttatca cttccattat cctgataaaa
    17281 atagaacagc taaagaatgt ttagatgaga tagaatatgc ttttgcacac tatctaccag
    17341 cagaagaggt agctgcaata tttatagagc caattgcagg agatgcagga ataatagtgc
    17401 ctccagtaga gtgggtacaa ggtttaagta aaatatgtaa agaaaatgga atattacttg
    17461 taagtgatga aatacaacaa ggtatgggaa gaacaggtaa gtggtttggt atagaaaatt
    17521 ttggtgttga agcagacctt atagttcttg gaaaatctgt tggaggtgga ttacctctag
    17581 gagcagttgt tggaagaaca gaaataatgc aaagtcttga tgcaccagca catttattta
    17641 ctttagctgg aaacacaaca gtatgtgtgg ctgctttaaa atctatagag ataattgaaa
    17701 aagaaaactt acttcaaaag agtatagaaa tgggagatta tattaaagca ggatttgaaa
    17761 aactaaaaga aaaatacgat ataattggag aaataagagg cataggatta tctataggag
    17821 ttgatatagt taaaggaaaa ggttctaatg aaaaacatcc agatgctaca gctaagatat
    17881 gttatagatg tatacaaact ggattaataa tgatattctt aggacaatct actttaagag
    17941 tgcaaccacc tctagtaata actaaggagc aagtagataa agcaatgaac atcatagatt
    18001 ctgcaataga tgattattta aatggtagaa ttggtgatga agtatatgaa gtaactcaag
    18061 gttggtaaaa taaatattaa atgaaaatag gagttatctc aattttagaa aattatttct
    18121 gaaatgagat aactctttta agttacccac aaataagaaa attgtttgat tcattaaaga
    18181 ctatatttcg gatgtcgttt ttgtgagtat cagagacagt attacgagaa taattacctt
    18241 tattcgtact atctgttaat ttagttataa ttaagatagc taaaagaata agaattactg
    18301 tgtataaagc aataacatat ggttttcttt tatatttgta tttgttattg aaaaaagaat
    18361 ggccataatt atttttattt actttagatg tatttgtatt ctttttcttg ttacctttct
    18421 ttttatcatc cttttttcta tttttagggt aaggaatgac tttgtgtgta ttatcaagtt
    18481 tgatattttt atttttttga atattgtttt ccaggctagc ctttttttct ccaaattgaa
    18541 tagttttatt ggtattgttg ttatctttca atgttaatct ccctccctta aactttccct
    18601 ttagataata ttactactaa cctatggaat atacaataaa taatatataa gtaataaaat
    18661 tttataggta taaatctctt tctccacgct ctaaggcagt catattgtta gatactatgt
    18721 ttcttatatc ttctctttct atcttaccta tttcttctgc gataagtttt ttacccataa
    18781 ttttaagttc ttcatctcca taatcgatta aaaattcatt taatgtagta agagcatttg
    18841 gtgtacatac attatggatt tgtcgacttt tagctaagct catgaatcta tcgccagttc
    18901 tacctttacg ataacaagct gtacaataac taggtatata tccatcagta atcagttctt
    18961 taagcacctc aacagggctt ctatggtctc caacttcaaa ttgttctgta ttgtcaccat
    19021 cttcatatgc tttatatcct ccaacacctg ttagagaacc tgcactaatt tgtgatacac
    19081 catattttag taactcattt ctcatttcag cagtttctct agtggacatt atgattccag
    19141 taaaaggaac agctaatcta gttatagcta ctattttttt gaacatatcg tcagaaacta
    19201 agtgaggaaa atcttctaag ctcatacctt cagctttttt caatctaggg aaagatatag
    19261 tatggaaacc tacaccaaat ttttcctcta agtgttcgtt gtgcatcata agtcctagaa
    19321 cttcaaattt agggtcagat aaaccaaata aaactcctgc accaacatca tcaacaccag
    19381 cttccatagc tctatcaaaa gctgttaaat ggtaataata gtcatttttt atagattgac
    19441 catgcatttt tataaatgtt ggtttgtgat aagtttcttg gaataatata taagttccta
    19501 ttcctttttc ttttagtaat ttatactcat ctacacttgt agctgctatg ttaacgttta
    19561 cccttcttat atttccgttt tcattatatg ttgaataaat tgcatctaag caatctaaga
    19621 tgtaatttat atcacaattt ttagggtctt caccagcttc tagagcaagt cttttatgac
    19681 ccattttttc taatatttta acctcttcct ttatctcttc catggtaagt ttttttcttt
    19741 taaatttgtt gcatttacta aaaccgcaat aaacacattc atttacacag tagtttgata
    19801 cataaagagg ggcaaataaa accactctat taccatatat ttcatttttt atttgcccag
    19861 ctatactaaa taatctatct agttgttttt tatcttctac ttcaagaagt gtagctatat
    19921 ctttataact aagtttttcc cttctatcag ccttatcaag taccttttca atatcatcag
    19981 aagttgaatt ttttgcatct tctaataaag aattaataag ttcatggttt atgaacattt
    20041 acaaacgcct ccattcaata ttatcaccgc gagaatagtc aacttcaagt cctaatgact
    20101 tgatgttttc ttctaaactt tggtgatatt cacaagcttc ttgaccagta aaggctttgt
    20161 tatcgtaaag agaatattgt tttctaaatt cttgaggaga aaggtttggc ataattacat
    20221 tgcaaccagc taaaagacct gcatttctac cactagggtt tatagatgcc aaggctgttg
    20281 tagcgggtaa taaaactttt ggaagtagaa gtcttgtaat tgaaagcata agtaatgtct
    20341 tctctaaatc tccatgttta taatccttaa aaattgtatc atggtgtgga ataaaaggtc
    20401 ctattccaac catatgagga tttaactctt ttaggtataa taaatcacga acaaggtctt
    20461 cgttgttctg aaatggtgat tcaaccataa atccagcacc tacctgataa ccaatttctt
    20521 taaggttttt taggcattct tttctagttc taagctcaat gtttggcgga tgtaattttt
    20581 tataatgact gtctgtagca gtttcatgtc ttaaaagata tctatctgca ccacataaaa
    20641 agtatttttt atacgaatca taactctttt ctcctagtga tagagttatg gcacaatcct
    20701 catatttatt ttttatactt gaaacaattt cacatatttt atcatcagta aaatatgcat
    20761 cttcaccacc ttgcaaaacg aatgttctgt atcctatttt ataacctata tcacaacatt
    20821 caagtatttc atcaagtgaa agcctgtatc ttatgatatt tttattagaa gattgtattc
    20881 cacaatagta gcaattattt ttacaatagt ttgtaagctc tataagtcct ctcaagtaga
    20941 ctctatttcc ataatgttta tttctcatgt cgctagcttg tttataaaga tagtttctta
    21001 aattttgttc gaagttatat tcctcattgt cgatattttc tattaaatat agtagttcat
    21061 caaaacttaa tgaattaatg ctgtaaagtt tatctataaa gtatttaatc ttatttttag
    21121 tcatattcaa atatgtaatt attaagtata gttaaatttt taataattga aaagttcaag
    21181 tgatctttcc aaaatacctt ttacatatgc tattaagaca ccatagttta caataggtac
    21241 attgaaagat tttgcctttt ctattctaga taacattcca gctctattca tcatacaagc
    21301 tccacagtga actacaaggg catatttatt tatatcttca gtgaaggata ctccagaact
    21361 aaattcaaaa gtaatgtttt tgccagtttt ctttctaatc atattaggaa tttttactgt
    21421 tccaatatca tcagtttgtc tatgatgggt acatccttcg gccatcaaga ttttatcacc
    21481 atcttttaaa ttttctaaag cataagctcc attaatcaat tctttaaggt ctcccttttg
    21541 tctagcaaac aatatagaaa aagatgtaag aggaatatct tttggtgtat ctttatctac
    21601 ttgtggaaat acttgagagt cagtaataac aagttttggt tttttgccta aattagatag
    21661 agtttctttt aaactatctt cttttgtaac tatagaaatt gcaccattat ccaaaatatc
    21721 tcttataact tgctgttgag gaagtataag tctacctttt ggagctgctt tatctattgg
    21781 aacaactaaa acaactaaat catttggttc aattaaatct gataccaatt tgaactcagt
    21841 gctatcctta ggcaaaactt ttattatttc attttttaaa ttttcaattc caattttatc
    21901 tgttgatgag acagaaacaa ctggacattt aactttattt ttagttaagt ttaaaatttc
    21961 tgattgattc ttaatagtat caattttgtt gagaattaga atatgaggga tattcttatc
    22021 attaaatttt tcaattagtg acaaatcttc ttgtgatata ccaatttggc aatccactac
    22081 tagtaaagct atatctgtct tttctaaaac atctagtgat ttacctattc taagttcacc
    22141 aagttcacca acatcatcaa gaccagcagt atctataaga acacaaggtc ctataggaag
    22201 gatttccatt ggtctaaata ctgggtctgt agtagttcca gcaatatctg agactattgc
    22261 agcactttga tttgttatag catttattat gctagattta cctgcatttc ttttaccaaa
    22321 gagacctata tgtactctta ccgattgtgg agtagaattt agactcattt gtactcacca
    22381 ccttaaactt ctttttttga tatactagtt tttacagata catgaggtat gttgcccaat
    22441 ttaccagtca aactattaat agtatccatt tcgccaacaa ctgctataca tacgattgag
    22501 acaccttctt cttcgcaagg aatgcccatt cttcctttaa taataccttt aaaacctgat
    22561 acaacctcat tgaatttaaa ttgacattct tttggctctt ccaaaatagc acttataact
    22621 gcaacctttt tcataaatat cctcctaact cagaaaatat gtcttaaaca aatccaaaat
    22681 caaaaaactt ttctttgtaa agaaaagttt ctacaaaaga aaagttatta attacacaag
    22741 tataatgtgc tatattaaac tatttcctta cagattagat aactcttttc tggtagggtt
    22801 agcttgtaaa aatttaattt aacaacaagt aactgaagaa aatttttata caatttatat
    22861 aaattataat aaaaattaac taaagaaaat tgaagttact tatataatag tagtaaattg
    22921 aaattaagtc tatagaaaaa ccaatttttg tataaaaata aaaattaaag ttaattattt
    22981 gttaagaatt gactttggta aaatatataa ttaattattc tttaagcata taatttataa
    23041 gtaattttag tgtattttca atagcttcta tatgtgttct ttcataatgg tgactattgt
    23101 ttgttccagg accaacacat gctatttgaa catcttctcc ccaacgaata gcttctgaag
    23161 catctgaacc atagaaagta aatacatcga cagcgtagtc taaattattg tcttctgcaa
    23221 catcaacaag cttgtttctt aaattaaaat catataatga taaattatct tttgcaacta
    23281 tagttacacc atgttcacta gatgtttgac ttggtccagt aggtgctata tctattgcta
    23341 caaattcttt tgttttttca ggtaaacatt tagaaacacc atgtccaatt tcttcataat
    23401 tacttatata aaagttagta gtatgcttag gtgttaaatt gttttcttta aaatatctac
    23461 atatttcaag aaccattgct acagctgatt tattatctat atatctagat tttataaaac
    23521 cagattctgt agcctcaaat ctatggtcta ggcatacaaa atccccaaca cttattccta
    23581 aatctaatac atcttgcttt gtaaatactt tttcatcaag tctaataatc attgtttctt
    23641 catttctttc agtggcagct tttgtttgac catatatatg agtagaagca tacttaaata
    23701 caacacttcc tctgattttt ttaccttttc tagttataac agtacagttt tctccctcta
    23761 tagctgccca acatccacca ccaactttat ggtatttaag agtaccatca gatgatattt
    23821 cttttactat agctccaagt gtatccatat gtgcagatat tgttatttga tttgaatcat
    23881 cttcaccagg aagagtagct ataagtgcac ctttttttgt aagaatagtg tcaagaccta
    23941 aattttcaaa atcttttttg atttctaaaa ctgcattttc agtatatcca gctgggcttg
    24001 gaatgtccaa atattttttc attaaattta tagtattagt taaatttaaa ttcatattgt
    24061 ttcctcctaa ataaatatat ttatacaaat tataacataa atacaaatgt tctgaaaact
    24121 aaaattaaaa gaatagaatc taaacatatt taaaaaaaaa
//
LOCUS       DAEORM030000057        22819 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.057, whole genome shotgun sequence.
ACCESSION   DAEORM030000057 DAEORM030000000
VERSION     DAEORM030000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 22819)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22819)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 22819)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22819
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.057"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            complement(82..2301)
                     /locus_tag="KRH23_002974"
     CDS             complement(82..2301)
                     /locus_tag="KRH23_002974"
                     /EC_number="2.7.7.65"
                     /EC_number="3.1.4.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0052621 - diguanylate cyclase activity
                     [Evidence IEA];
                     GO_function: GO:0071111 - cyclic-guanylate-specific
                     phosphodiesterase activity [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="HHS5226251.1"
                     /translation="MTGRNKSFTLITILFLTSLFLTMGYIYIEDTKHLLMSEAKIHIK
                     EVAVQGSQLAQRQIEKDLDVLNIFSNYYASNPDIPNEEKMKNLLDEMENQKFYTMAIV
                     DINGNAENTKGDKFSVKDREFFKNSIKGKKYVSSPYVDEVNKSIKKIAISVPLLNNDK
                     VVGVLYCTYNINTLMKLINISFYENNSISYVVKNDGTIILHPQGDSLSKNIYKLLEQD
                     NDIHEVNRLKKELQENKTGATVLNMLEERRYLGYATMDNGNSENNYIKDWNLIFSIPE
                     TVVFSNSKQIINRAVYAVLSIVLIFVAIIFYIIYIKKSNEKEILSLAYEDKVTYIGNQ
                     NKFYRECSKYLLDKPSLNYIIVYFDINNFKMINDTFGYEFGDNLLITIAKALKEELTE
                     GEVYARLSSDYFAIFCDYKNGRNKIIRKLDNIRSNIESNLSIVFEISLCVGIYFVEEG
                     EVDIQKAVNKANMARSVAKGKNINYAIYNEDVRNKLSEESMILDDIKIALVKNQFEVY
                     YQPKFSLVTGEMIGSEALIRWNHPEHGFISPAVFIPIAEKSKLILKIGRFVFERVCND
                     LSEWKKQGKKIVPVSVNLSRVELYQPDIVKFINKTIQMYNLSSDFIEIEITETVAINE
                     LNILKNVLNELRKHGFSISMDDFGTGYSSISCLRDMPIDILKLDKSFLGGIEHDERSR
                     NIAKSIVSLAKSLDLVVIIEGVESKEQAELMKQFGCDLVQGFYFARPMPAKNFLDLL"
     gene            complement(2578..5232)
                     /gene="adhE"
                     /locus_tag="KRH23_002975"
                     /gene_synonym="adhC"
     CDS             complement(2578..5232)
                     /gene="adhE"
                     /locus_tag="KRH23_002975"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004022 - alcohol dehydrogenase (NAD+)
                     activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006066 - alcohol metabolic process
                     [Evidence IEA];
                     GO_process: GO:0015976 - carbon utilization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HHS5226252.1"
                     /translation="MAHKEQIIIENKKENEVMSVGLDTVNNVESLVKKLAKIREAQKI
                     FATYSQEQVDKIFLAASLAANKQRVPLAIMAQKETGMGIAEDKVIKNHYASEYIYNAY
                     KETKTCGVIEKDEAFGMTKIAEPIGVIAAVVPTTNPTSTAIFKALLALKTRNGIIFSP
                     HPRAKNSTIEAAKVVLEAAVLAGAPEGIIGWIDEPSLELTTTVMKEVDLTLATGGPGM
                     VKSAYSSGKPAIGVGAGNTPAIIDDSADIKTAVNSILVSKTFDNGMICASEQSVIVLE
                     NIYNEVKKEFKERGAYLLDKDETEKIRNIILVNGGLNSKIVGQTACTIAKLAGFEVPV
                     DTKVLIGEVESVDIEEAFAHEKLSPVLAMYKASDFDDAVRKAEKLVEDGGFGHTSSLY
                     IDDVNQREKLDKFTSAMKTCRILINTPSSQGGIGDLYNFKLAPSLTLGCGSWGGNSVS
                     ENVGVKHLLNIKTVAERRENMLWFRAPEKVYFKKGCLGVALKELKDVMNKKRAFIVTD
                     TFLYNNGYTKAVTDLLDEMNIKHTTFFEVEPDPTLECAKIGAKAMREFNPDVIISIGG
                     GSAMDAGKIMWTLYEHPDVDFQDLAMRFMDIRKRVYTFPKMGEKANFVAIPTSAGTGS
                     EVTPFAVITDQDTGVKYPLADYELMPNMAIVDSDMMMNMPKSLTSASGIDALTHALEA
                     YVSMLATDYTNGLALQAIKSIFEYLPRAYDNGAKDPEAREKMANASTMAGMAFANAFL
                     GVCHSMAHKLGAFHHVPHGVANALLITEVMKFNSSDAPKKMGAFSQYKYPEALKRYAE
                     IASFLGLKGNSDEEKFQSLLVAIEDLKLKVGIPKSIKEFGVEESKFMDSIDEMVIQAF
                     DDQCTGANPRYPLMNEIKDMYLNSYYGR"
     gene            5736..5936
                     /locus_tag="KRH23_002976"
     CDS             5736..5936
                     /locus_tag="KRH23_002976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226253.1"
                     /translation="MKKLKTISVFSLIISVILTIGGIGIVTYYVDNLFIRGLSVFVLI
                     MSSSFVSTTVRLIFEESKRYKF"
     gene            complement(6143..6733)
                     /locus_tag="KRH23_002977"
     CDS             complement(6143..6733)
                     /locus_tag="KRH23_002977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dipicolinate synthase subunit B"
                     /protein_id="HHS5226254.1"
                     /translation="MRLEGLTIGVGFTGSFCTYDKIFIELENLVKEGANVHTIFSDVS
                     QNIDCRFGNSEEFMKKAYELTGNKPIVTIEEAEPFGPKGIADIIIIAPCTGNTAAKLA
                     NGITDSPVLMAAKGHLRNDKPLVISISTNDALSFNFKNIGILLNSKNIYFVPFGQDNC
                     KAKPNSMIAHTELIIPTIELALENKQLQPVIKSPHQ"
     gene            complement(6736..7611)
                     /gene="dpsA"
                     /locus_tag="KRH23_002978"
     CDS             complement(6736..7611)
                     /gene="dpsA"
                     /locus_tag="KRH23_002978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipicolinate synthase subunit DpsA"
                     /protein_id="HHS5226255.1"
                     /translation="MSNQYDITVIGGDLRQVYMVKKLINKGYSVVTYGISNEIINGIV
                     GKSTSLAEALSKSSIILCPIPFTKNQVNIENTDDCLDATIDNLLINLSPNQILFGGNI
                     PTKVCKFCEQHSIQIYDFMKMNDVAILNAVATAEGAIAEAIKRSIINIHQSNCLVLGY
                     GRCAQILAKKLYALDANVCVGARNNDARSTANAFGYSSISLSQLDEKLLQFDYIFNTI
                     PECILTKERLEKVSQEVTIIDIASSPGGVDYSVVKEAGINATLCLGLPGKYSPKTSGE
                     ILVNAIENIINERRD"
     gene            complement(7687..9078)
                     /locus_tag="KRH23_002979"
     CDS             complement(7687..9078)
                     /locus_tag="KRH23_002979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HHS5226256.1"
                     /translation="MNYYELLRIKKERHKNKNFLIIDGEKYTYENILSYSEELGKQIS
                     LGENIPILIYSKNIMFQLISFFAINYSKNIPIICHYNLSKKVLDDILLKNNISIIISD
                     ESMDVIDLYDDNNNEVAKKVNFSIFNPKFNIYMYQYKNLINYLDKSICMGALSSGSTS
                     VPKVLYRTYESWAGFFPIQNGIFNISGESILFVNGTLSFTGNLNSIMSVLYEGGSIVI
                     SSGLNCKSWIRTIKQYNVTNIYLIPTKLQLLVKHLKEPVLKVVSIFTGSQLLFEDTAR
                     NLKKYMPKSEIILYYGASELNYITYLCYDELIEKPLSVGRPFPGIDIYIREGKIFVNT
                     EYAVYNATKPYSVNDIGYYDNDGYLIFEGRSDDIVNIGGFKVSSTKIENEVKKIPQIE
                     DAIVLPYSDTIRGNQIVLFVITIDKITKKDLLIKMKDNLMKNEIPKKIIFLNSFPYTS
                     SEKIDRLALLKML"
     gene            complement(9082..10218)
                     /locus_tag="KRH23_002980"
     CDS             complement(9082..10218)
                     /locus_tag="KRH23_002980"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiolase family protein"
                     /protein_id="HHS5226257.1"
                     /translation="MKEVFILGGLRSHIGLKNGIFQFVQPELLGASVLKDLIKKYEID
                     KIDEIICGNAVGTGGNIARLMTLTAGVSNEVPAFTVDMQCASAMMSIDIAFSKVKSGQ
                     CDLIIAGGFESSSLQPMRTYHKNDKRYDTNNPNYTVAQFSPDDNSQNSMLEGAERVAE
                     LYQIEKADLDFWVKESHKRAKEAREEKILEDIISPINNSTYDEGIRDKMSQRLLDRMP
                     SILGKETITNAANSCLINDGASFIIICSKKYLEHVKKKPKAKIINTCTIGTDATLSPT
                     SAIQAMDKLLEIESLNYLDVSAVEFNEAFAVIDVLFQRKYPELIDRYNIFGGALAYGH
                     PYGASGAIITLHLLKALEKTKGRYGICSIAAAGGLGSALLLERV"
     gene            complement(10250..10795)
                     /locus_tag="KRH23_002981"
     CDS             complement(10250..10795)
                     /locus_tag="KRH23_002981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HHS5226258.1"
                     /translation="MKNTKVNIQDLTKMSICVALLCISSYIYIPLPFTPAGVTAQTIM
                     INLIALILTPRQAFSTVGVYIMIGLIGIPVFGGGTSGIGKLLSPTGGFYFGFLFAALI
                     ISLLKGRNNDIKRYILITIFVGMPIIYFMGTVFMCYFNQMTVEAALFAAVVPFLIGDT
                     IKSVIASFLGTKLNNVLRRNL"
     gene            11119..11898
                     /locus_tag="KRH23_002982"
     CDS             11119..11898
                     /locus_tag="KRH23_002982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226259.1"
                     /translation="MKVNENNINNIDEELDELSRKVYLESPDFWISISDKIIDKVFDE
                     MLLFFAVKYNYFNIVCFAIENNYLDLNMPSKNKKYTNIMEHLLDTSTQNEDKKIYNYL
                     LSLNKGYRLDERPILDELNCNISSDTFEKKDIYLPKYLCPSCNSNIFDTGYKVSNDIT
                     YKFSSKEAEPIEMCSEVSSIRCCNCDELLEDITLDKLYNLCKIQNCNNCGSNLTKVGI
                     IAKKKMNFDENTEKFKDVSTSYCCGNCDSEINLSQREHFKI"
     gene            complement(12353..12781)
                     /locus_tag="KRH23_002983"
     CDS             complement(12353..12781)
                     /locus_tag="KRH23_002983"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HHS5226260.1"
                     /translation="MIKKLNNKDINKIMEIWEKSTIKAHDFISKEYWQNNYNTVKNEY
                     IPISDTFVYDDGDEIKGFISIIDKSFIGALFIKPKYQNLGIGGKLLDYATKKYKSLSL
                     AVYKDNKKAVVFYNKKGFNIVKEQVNEDSGFKEYIMEYSK"
     gene            complement(12977..13210)
                     /locus_tag="KRH23_002984"
     CDS             complement(12977..13210)
                     /locus_tag="KRH23_002984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HHS5226261.1"
                     /translation="MMILIQSRGKMKCKELSEELEVSERQIKSYKMYLEQAGIFINST
                     PGIYGGYEIDKCSSISLIKLLDSEVPIFISTKW"
     gene            complement(13489..15405)
                     /locus_tag="KRH23_002985"
     CDS             complement(13489..15405)
                     /locus_tag="KRH23_002985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HHS5226262.1"
                     /translation="MNIKQFAINNISRNIKAYLGYLASIVISSSLLFSFIMFTSHPDL
                     DVSQFPDYLKEGLKMSKIIAYLFLFFFVFYSVSVFLKSRYKEFGILYITGISKRQVMK
                     LIFIENMIINIVSSVIGIIIGLIFAKIFLVIMSTFLELSPLKFYIPFNAILSTLIYFM
                     ILAVLTSIFTSFIVKENQVLKLLKGTKTPKPEPKTSLMLAILSICLFIIAYYNAITST
                     DQYTTYLRLVPVTSLTIVATYLFFSQFSVFFMKKLKLNKRFYRKNTNMLWISNLIYKV
                     KDNARIFFLITITSAVAFTAIGTVYSFWKDVERQINLIYPNTIYYSTMTLHNDPKKPD
                     SKEKDKERMMFIENNLKKENVDYTRTNGEFKTVFPKKSDFNVRIMKESKYLEITETIG
                     VKPISFEDNECISLLSSSLPGNNNVKENIIVGNRGLKVAKQVEECVMPAYYKNMYVVK
                     DNFYDSIESKFIVDRFTAFEVEDSSKTIEICREFENKFNNESGMQPYLFFSKELMIGT
                     GKLMYSTFIFLAIFIGLIFFVTTSSFLYNKFYMDCQVDKKKYEQLNKLGMTYNEIKKA
                     STIEIGIVFLFPYVVAVIHSIFALTALKNSFDIEVASSAVLVMGSLFLVQIVYFLIVR
                     NNYLKEIRLNLVNF"
     gene            complement(15405..16151)
                     /locus_tag="KRH23_002986"
     CDS             complement(15405..16151)
                     /locus_tag="KRH23_002986"
                     /EC_number="7.6.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHS5226263.1"
                     /translation="MKILTVNNLSKVYGKKIIFNALNDINFSIEDGEFVGIMGPSGSG
                     KTTLLNMISTIDKPTTGTMELKGKNPLLLRGEELALFRRRELGFVFQDFNLLDTLTIG
                     ENIVLPLTLDKVSVKEQDERLNEVSTILGIKDLLGKRTFEVSGGQAQRTAIARALINN
                     PSILLADEPTGNLDSKSSKVVMELFQKINKENKVTTMMVTHDPLAASYCSRILFIKDG
                     SIYNEIYKGSSREQFYQEIMDVLTLLGGDN"
     gene            complement(16255..17106)
                     /locus_tag="KRH23_002987"
     CDS             complement(16255..17106)
                     /locus_tag="KRH23_002987"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0050380 - undecaprenyl-diphosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0016311 - dephosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HHS5226264.1"
                     /translation="MSLDVIFILKSVIIAIVEGLTEFIPVSSTGHMILVGNLIDFKGQ
                     FAEMFEVVIQLGAILAVVVLYWKKIKDSVIEFFKFIFTGGKEGKIGFRFGMNVIIGCI
                     PFAIIGVLFYDNIKSLFNLQSVIIGFIVGGILLLVVETLFRKKNPSTDNIDKITPIQA
                     LKVGTLQVLSAWPGMSRSASTIMGGWIAGLNSPTAAEFSFFLAVPAMVASSGKDLFEF
                     DYSIMTPTLWIALVVGFIVAFIVSIIVMEKFVNFLKKKSMRVFAVYRIIMGVVLAVLA
                     FTNIISV"
     gene            complement(17354..18127)
                     /locus_tag="KRH23_002988"
     CDS             complement(17354..18127)
                     /locus_tag="KRH23_002988"
                     /inference="COORDINATES: protein motif:HMM:NF014567.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HHS5226265.1"
                     /translation="MYLGSSFLGRNISVILKQQHKLYQSMIQEHKKIHSEHLTFINQW
                     IHQMKTPISVISLQLQDYEGEEVTENIRKEIDRLNKGLDMAMHFARADNFQKDFIVEK
                     AKLNEIVSSIVNEEKRLFIKSGMIPKIQVDKFTYVYTDVKWMKFIIGQLITNGVKYSK
                     DYSNYLTIKSEENNKYVILSIIDEGIGIVSKDLKRVFDPFFTGENGRKFGESTGMGLY
                     LVKKVCDDLGHKVSIKSEVGKGTEVSIYFNKDVNSLIKV"
     gene            complement(18368..19060)
                     /locus_tag="KRH23_002989"
     CDS             complement(18368..19060)
                     /locus_tag="KRH23_002989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HHS5226266.1"
                     /translation="MSYKVYIVEDDISISTLLKDYIEKYGFEVIVEENFDDIMITFES
                     FKPHLVLLDVNLPKFDGFYWCRCIRQQSNLPIIFISARDGNVDQIRALESGADDYITK
                     PFYYDVVMAKIKSHIRRVYGEYSPKIDERIVELDGLKFYPERLELELNGENLIITKKE
                     GILIECLIKRYPKVVSRDYLLEKIWDDIEFVEENTLNVNVSRIRKRFEELGIDNAVQT
                     VRGLGYKLNKNW"
     gene            complement(19374..20333)
                     /locus_tag="KRH23_002990"
     CDS             complement(19374..20333)
                     /locus_tag="KRH23_002990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HHS5226267.1"
                     /translation="MKLKKLLIGITILTLATASLAGCAKKNNGEKLSEINLTYVKSPL
                     NVPSIIQKQDDLFGKEFKKDNIKVNFHEITTGPEQTQALAAGEIDFLHALGGTSALIA
                     ASNGVELKILNTYSRSPKGFMILTNNNSIKSAADLVGKKVAGPKGTILHQVFISALDK
                     EGLSMDDVEFVNMGIPEASAALSDGSVDAALIAGPAALKAMKSGSKLVANGEGLVDGI
                     IVTAVSTDFAEKHPEIVERFMKVEKETLEYVNNNFDEAMEKVAKEVDLSLEETKELYA
                     WYDFSLDITDKDISSLEDTQDFLIKNKLQEKKVNIKELIYNAK"
     gene            complement(20366..21244)
                     /locus_tag="KRH23_002991"
     CDS             complement(20366..21244)
                     /locus_tag="KRH23_002991"
                     /EC_number="7.6.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHS5226268.1"
                     /translation="MNNLVCDSGYIIRNLYKSYKVDNEEHVVLSDISLNIDRNHITVI
                     LGESGCGKTTLLRAIASLEGINSGEIRFINDNKEYRPNVGFVFQESRLMPWLNVSENI
                     AFHNQRKNTILNKVLRKFKHNKRISSKIINDNFRSLETNDNLNKSNKYNRKSNIDVEK
                     YLKMMNLQKFKNSYPNELSGGMAQRVSIARALSFNPDMLLMDEPFSALDYFTRIDMQN
                     EVIRIHKSTNKGVIFVTHDIDEALKIGKKIVVFTDERKIKEFNIEDGYNRDLTSDYYI
                     KLKKDILMTMKSNKGI"
     gene            complement(21237..22019)
                     /locus_tag="KRH23_002992"
     CDS             complement(21237..22019)
                     /locus_tag="KRH23_002992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHS5226269.1"
                     /translation="MVNKFNNKFLRLVKSVLIFFIILLLWKITNYLGIWSDYILPSPE
                     KVYSTFLNMISDGSIFINVYASMKRVLIGFAISTAIGVPLGIFFGIYSGVYEYFKSLI
                     NFLRNTPPLALIPMLILWFGIGEESKIIIIVLASFFPIFTSTLKGIKNCDSKLIEVGR
                     VFEFSKLQIIFKIIIPNAILDIAVGLKLALGYSFRAIIGAELVAASSGLGYLISDGKE
                     MSRTDVVIVGIIVIGLLGIITDYIFSIIVKKVSKGKMVEAYE"
     gene            complement(22020..22649)
                     /locus_tag="KRH23_002993"
     CDS             complement(22020..22649)
                     /locus_tag="KRH23_002993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226270.1"
                     /translation="MNKYLLINPVAERMYGEKFHLIKANLIKKGYIIAECEPQLEYVK
                     KQYKEYTKKTENTMLDCRCPESISLLKRNNLINDFEVPMIEPILVRTCRVLYDKYIKS
                     KDDMLVVTCPCTQLRDFASETFKDKGNAMFYTWKEFAEQEGVKSLGKIDESPIPLGYF
                     KDTFEKVLEVSSEDEILSEIQKIRNGFEDKYDIVEMFYCKDGCNNGDGL"
BASE COUNT         7746 a         3820 c         2359 g         8894 t
ORIGIN      
        1 aaaaaaacac taattattta gcagtgattt attaaaatca agcattcata atagtgcttt
       61 atataaaaat caaattttgt tttaaagtaa atctaaaaaa ttcttagctg gcattggtcg
      121 tgcaaaataa aatccttgaa ctaaatcaca tccaaattgt ttcattaact cagcttgttc
      181 tttactctca acaccttcta taattacaac taaatctagt gattttgcta gagacactat
      241 tgattttgct atattgcgac ttctctcatc atgttcaatg ccaccaagaa aagacttatc
      301 tagtttcaat atatcaattg gcatatctct taaacaacta atagaagaat atcctgtgcc
      361 aaagtcatcc atagaaatag aaaatccatg cttcctcaat tcatttaaaa cattctttaa
      421 aatatttaac tcattaatag ccacagtttc tgttatctct atttcaatga aatctgaact
      481 tagattatac atttgtattg ttttattgat aaattttaca atatctggtt gatacaactc
      541 gactctagat aaatttactg aaactggaac tatcttttta ccttgctttt tccattcaga
      601 taaatcattg caaacccttt caaatacaaa tctcccaatt tttaaaatca acttactttt
      661 ctctgctatt ggaataaata ctgcgggact tataaaacca tgttctggat gattccatct
      721 tattagtgct tcactcccta tcatttctcc agttacaagt gaaaacttag gttgataata
      781 cacttcaaat tgatttttta ccaatgctat ttttatatca tctaaaatca ttgattcttc
      841 actaagctta ttcctaacat cttcattata aatagcataa tttatatttt tacctttagc
      901 aacagaccta gccatatttg ctttatttac agccttttga atatctactt caccttcttc
      961 aacaaaataa atacccacac acagggagat ttcaaagact atactcaaat tactttcaat
     1021 attacttcgt atattatcaa gttttcttat aattttattt cttccatttt tataatcaca
     1081 gaaaattgca aaataatcac ttgaaagtcg tgcatatacc tcaccttctg ttaattcttc
     1141 ttttaaagct tttgctattg taattaataa attgtcacca aattcatatc caaaagtatc
     1201 attaatcatc ttaaagttat taatatcaaa atatactata atataattta aagatggttt
     1261 atctaaaaga tacttactac actctctata aaatttattt tgatttccta tatatgtaac
     1321 tttatcttca taagccaaac ttaatatttc tttttcatta gattttttta tataaattat
     1381 ataaaaaata attgcaacaa atattaatac aatagataac actgcatata cagctctgtt
     1441 gattatttgt tttgaattac taaatacaac agtttctgga attgaaaaaa ttaaattcca
     1501 gtcttttata taattatttt cactattccc attatccata gtggcatatc ctaaatatct
     1561 tctttcttcc aacatattta atacagttgc acctgtttta ttttcttgca attctttttt
     1621 taatctattt acttcatgaa tatcattatc ctgttctaac aatttataaa tattttttga
     1681 taggctatcc ccttgtggat gaaggataat tgtaccatca ttttttacaa cataagatat
     1741 actattattt tcataaaaag atatattaat aagtttcatc agagtattga tattgtaagt
     1801 acaatataaa actccaacta ctttatcatt atttaataat ggtactgaaa tagcaatctt
     1861 ctttatagac ttatttactt catcaacata tggacttgaa acatacttct tacctttaat
     1921 tgagtttttg aaaaattctc tatctttcac tgaaaactta tcacctttgg tattttcagc
     1981 attaccattt atatcaacta ttgccatagt gtaaaatttt tgattttcca tttcatctaa
     2041 aagatttttc attttttcct cattaggtat atctggattt gaagcataat agttagaaaa
     2101 aatatttaaa acatctaaat ctttttcaat ttgtctttgt gctagttgag agccttgtac
     2161 tgcaacttct tttatatgta tttttgcctc tgacataaga agatgtttcg tatcttctat
     2221 atagatatac cccattgtca aaaataatga tgttaaaaaa agaattgtaa ttaatgtaaa
     2281 acttttattt ctccctgtca ttcgactcct cccctaatta gtcaatactt catatagata
     2341 atatatcctt tttataccaa ttcatcattt atattgtata taactattct taaatgttac
     2401 acataaaatc aacataataa ccataaaaac attcttttat tattataata acactattta
     2461 attgaatttt aaattaaaga ataaaaacta tccattttct caaacaaaaa aaactcttat
     2521 acaataaaac tttgttttat gtataagagt ttttatttta tctattttat agcaaactta
     2581 tcttccataa tatgaattta aatacatatc ttttatttca ttcataagtg gatatcttgg
     2641 atttgctcct gtacattggt catcaaatgc ttgaattacc atttcatcta ttgaatccat
     2701 aaacttagat tcttcaactc caaactcttt tatagattta ggaataccaa ctttaagttt
     2761 taaatcttca atagctacca ataaactctg gaatttctct tcatcagagt ttccttttaa
     2821 tcctaaaaat gaagctattt cagcatatct ctttaatgct tctggatatt tatattgaga
     2881 gaatgctccc attttctttg gtgcatctga agaattaaat ttcataactt ctgttatcaa
     2941 aagagcattt gcaacaccat gtggtacatg gtggaaagca cctaatttat gagccataga
     3001 gtgacaaaca cccaaaaatg catttgcaaa agccatacct gccattgtag aagcatttgc
     3061 cattttttct ctagcttctg ggtcttttgc accattatca tatgcacgtg gaagatattc
     3121 aaatatactc ttaatagctt gtaaagctaa tccatttgta taatcggttg caagcataga
     3181 tacatatgct tctaatgcat gagttaaagc atctatacca gaagcagatg ttaagctttt
     3241 tggcatattc atcatcatat cagaatcaac tatagccata tttggcatca gttcataatc
     3301 tgctaatgga tattttactc ctgtatcttg gtcagttata acagcaaatg gtgttacttc
     3361 tgaaccagta cctgctgatg ttggtatagc tacaaaatta gctttttcac ccattttagg
     3421 gaatgtatat accctttttc ttatatccat aaatctcata gctaggtctt ggaaatctac
     3481 atctggatgc tcatacaatg tccacattat ctttcctgca tccattgcac ttcctccacc
     3541 tatagatatt attacatctg gattaaattc tctcatagct ttagcaccta tcttagcaca
     3601 ttccaaagtt gggtctggtt ctacttcaaa gaatgtagtg tgcttaatat tcatttcatc
     3661 taataaatca gtaactgctt tagtatatcc attattgtaa aggaatgtat ctgttacaat
     3721 aaaagctctc ttcttattca ttacatcttt aagttctttt aatgctactc ctaaacaacc
     3781 ttttttgaaa taaacttttt ctggtgctct aaaccaaagc atattttctc tcctctcagc
     3841 tactgtttta atattaagta aatgcttaac tcctacattt tcagatactg aatttccacc
     3901 ccaagaccca catcctaaag taagagaagg agctagttta aaattatata agtcccctat
     3961 accaccttga gaagaaggag tattaattaa aattctacaa gttttcatgg ctgaagtaaa
     4021 cttatcaagt ttttctcttt gatttacatc atcaatatat aatgaagatg tatgcccaaa
     4081 tccaccatct tctactaatt tttctgcttt tctaactgca tcatcaaaat cacttgcctt
     4141 gtacattgca agtactggtg aaagtttctc atgagcaaaa gcttcttcta tgtcaactga
     4201 ttctacttca cctattaaaa ccttagtatc tactgggact tcaaagcctg caagttttgc
     4261 tatagtacaa gctgtttgcc caactatttt agaatttaat cctccattta ctaaaattat
     4321 atttcttatt ttttctgttt catctttatc taataaataa gcaccacgct ctttaaattc
     4381 ttttttgact tcattgtata tattttctaa tactataacc gattgttcag aagcacatat
     4441 cataccattg tcaaaagtct tagatacaag aattgagttt acagcagttt ttatatctgc
     4501 actatcatca attattgctg gagtattacc tgcaccaact ccaatagctg gttttccaga
     4561 tgaatatgct gatttaacca ttccaggacc tcctgtagca agggtcaaat ccacttcttt
     4621 cataacagtt gtagttaatt ctaaagatgg ctcatctatc catcctatta taccttcagg
     4681 agctccagct aaaacagcag cctcaagaac aacttttgca gcctctatag tagaattttt
     4741 tgctcttgga tgtggagaga aaattattcc atttctagtt tttaaagcta aaagtgcttt
     4801 aaagatagca gtagaagttg gattagttgt aggtacaact gctgcaataa cacctattgg
     4861 ttcagcaatt ttagtcatac caaatgcttc gtctttctct ataacaccac aagttttagt
     4921 ttctttatat gcattatata tatactctga ggcataatga ttctttataa ccttatcttc
     4981 agcaattccc ataccagttt ctttttgtgc cattatagct agaggaactc tttgcttatt
     5041 agctgccaaa gatgctgcta aaaaaatttt atctacctgc tcttgactat atgtagcaaa
     5101 tattttttga gcttctctga tttttgctag ttttttaact aagctttcaa cgttatttac
     5161 agtatctaaa ccaactgaca taacttcatt ttctttttta ttttctatta ttatttgttc
     5221 tttatgagcc attttaacaa cctcctgaga tagtttttta tttattatgt taatttatta
     5281 acattatagc atttactttt cctattttca agttattttt ttaacatttt attttttatc
     5341 taatataaca tcatttctac taataatatc tagctttaca aatacttaat ttaactagat
     5401 atcactttat tttttacgca aatcactaat gaaatcatct aaaaacttaa ggataacgtt
     5461 atttttttaa cgtttatatt tttgtatttt ttgcaaataa aactttataa aaagaatttt
     5521 taatatgata ctctatcaag tttaaaaata aaaatccttg aaaatgaaaa ttaaaactta
     5581 attaacaagt taaagtaaat atagttaaat gtacaaacat ttacaacata tagtataatt
     5641 aaaaaaatat atattcatga tttttatata atatgaaata aaatatattt aatattatat
     5701 agataaattt gaagtttata agaaggagga taagcatgaa aaaattaaaa acaattagcg
     5761 ttttttcttt gattataagt gtaattttaa cgattggagg tattggaata gtaacttatt
     5821 atgtagataa tttgtttatt agaggactat cggtatttgt tttaattatg tcctcttctt
     5881 ttgtatcaac aacagttaga ttgatattcg aagagtcaaa acgatataaa ttctaattta
     5941 aaaattggat taagtaaata attttaatat accaaaaatt acggagatta gctcaaaata
     6001 gactttttag tccatgaggc atttttttgt atgaaattaa atatattttc atcatttcaa
     6061 caagaaaaag aggcttctct ctattttgag acaacctctt tgctagtatt ttatctaata
     6121 cataatatta taagaaccaa ttctattgat gtggactttt tataacaggc tgtagctgtt
     6181 tgttctctag agcaagttct atagttggaa ttattagctc agtatgtgca atcatagaat
     6241 taggctttgc tttgcaatta tcttgaccaa aaggtacaaa atatatattt ttagaattaa
     6301 ggagaatgcc aatatttttg aaattaaagc ttagagcatc attcgttgat attgatatta
     6361 ctagtggttt atcattacga agatgacctt ttgctgccat taatactggt gaatctgtaa
     6421 taccatttgc taattttgca gcagtatttc cagtacaagg agctattatt ataatatcag
     6481 caattccttt aggtccaaat ggctctgcct cttcaatcgt aactataggt ttatttcctg
     6541 taagttcata tgcttttttc ataaactctt cagaatttcc aaatctacaa tcgatatttt
     6601 gtgatacatc tgaaaatata gtgtgtacat tagctccttc tttaaccaaa ttctctaact
     6661 ctataaatat tttatcataa gtacaaaacg aaccagtaaa tcctactcca attgtaagtc
     6721 cttcaagtct catttctaat cccttctttc atttataata ttttctatag cgttaacaag
     6781 aatttcacca gatgtctttg gtgaatattt accaggaagc ccaaggcaaa gagtcgcatt
     6841 aatccctgct tctttaacaa cagaataatc tactcctcca ggagaagaag ctatatctat
     6901 aatagttact tcttgtgata ctttttctaa cctttctttc gttaaaatac actctggtat
     6961 ggtgttaaaa atataatcaa attgtaaaag tttttcatca agttgactta aagaaatact
     7021 ggaatatcca aatgcattag ccgtacttct tgcatcatta tttcttgcgc caacacatac
     7081 atttgcatcc aaagcgtata atttttttgc aagtatttgt gcacatcttc cataacctaa
     7141 tactaaacag ttactttgat gtatattgat tatacttctt ttaatagctt ctgctatagc
     7201 cccttcagct gtagcaactg catttaaaat agcaacatca ttcattttca taaaatcata
     7261 aatctgaata gagtgttgct cacaaaattt acaaacttta gttggtatgt tacctccaaa
     7321 taatatttga ttaggagata aattaattag caagttatca atagtagcat caagacaatc
     7381 atccgtattt tcaatattaa cttgattctt tgtaaatgga attggacata aaataatgga
     7441 acttttggat agtgcttcag ctagtgaagt tgattttcca acgattccat ttataatttc
     7501 atttgatata ccataagtga ctacagaata ccctttatta attagttttt ttaccatgta
     7561 cacttgtcgc aggtctcccc caataacagt tatatcgtat tgatttgaca tattgtaagc
     7621 ctcctttact atatacaata tgtttttatc aatacattgg ttcactaaaa ttactaaata
     7681 ttatacttat aacattttta ataatgctaa tctatctatc ttttcagaag aggtatatgg
     7741 aaatgaattt aaaaagataa ttttctttgg gatttcattt ttcattagat tatctttcat
     7801 tttaatcaac aaatctttct tcgtaatttt gtctatagtt attacaaata atacaatttg
     7861 atttcctctt atagtgtctg aatacggcaa tacaattgca tcttcaattt gaggaatttt
     7921 tttaacttca ttttcaatct tagtagaact aactttaaat cctccaatat ttacaatgtc
     7981 atcacttctt ccttcaaata ttaagtatcc atcattatca taatatccaa tatcattgac
     8041 agaataaggt ttggttgcat tatatactgc atattctgta ttcacaaaaa tttttccttc
     8101 tctaatatat atatctattc ctggaaatgg tctgcctaca cttagaggtt tttcaattag
     8161 ttcatcatag cataaatatg taatataatt taattcactt gccccatagt ataaaataat
     8221 ttcagacttt ggcatatatt tttttagatt tcttgcagta tcttcaaata ataattgaga
     8281 ccctgtaaaa atacttacaa ctttgagtac tggttctttt aagtgtttaa ccaaaagttg
     8341 aagttttgta ggtataaggt atatgttagt tacattatat tgttttattg tccttatcca
     8401 tgatttacaa ttaagacctg aacttattac aatactacct ccttcatata atactgacat
     8461 tatagaattt agattccctg taaaactaag tgttccatta acaaacaaga ttgattcccc
     8521 agagatatta aaaataccat tttgtatagg aaaaaatcca gcccaactct catatgttct
     8581 atataatacc tttggaacac ttgtagaacc tgaagataaa gctcccatac aaatactttt
     8641 atctaaataa tttataaggt tcttatattg atacatatat atattaaatt taggattaaa
     8701 aatagaaaaa ttaacttttt ttgctacttc attattgtta tcatcatata aatcaataac
     8761 gtccatagat tcatcagata taatgattga aatattattt tttaataaaa tatcatctaa
     8821 tactttttta gaaagattat aatgacaaat aataggaata ttttttgaat aattaatagc
     8881 aaaaaaacta atcaactgaa acattatatt tttagaatat attaaaattg ggatattttc
     8941 acctaaagaa atttgttttc ctagttcctc actataactc aatatatttt cataagtata
     9001 tttttctcca tctataatta aaaaattttt atttttatgc ctctcttttt ttattcttaa
     9061 aagttcataa tagttcataa tctacaccct ttcaagcagt aaagctgaac ctagaccacc
     9121 agctgcagct atagagcaaa ttccatatct acccttagtc ttttctaatg cttttaaaag
     9181 atgtaatgta ataattgcac ctgaagcacc atatggatgt ccatacgcta aagctccacc
     9241 aaatatatta tatctatcta ttaactctgg atactttctt tgaaacaaca catctataac
     9301 tgcaaatgct tcattaaatt caacagcaga tacatctaaa taattaagac tttctatctc
     9361 taaaagttta tccattgctt gtatcgctga tgttggactt aaggttgcat ctgttcctat
     9421 tgtgcatgta ttaataattt ttgctttagg cttctttttt acatgttcta aatacttctt
     9481 agaacatatt ataataaatg aagctccatc attaataaga catgaatttg ctgcatttgt
     9541 aatagtttct tttcctaaaa ttgatggcat cctatctaat aacctttgac tcatcttatc
     9601 acgtatacct tcatcatagg tactattatt tataggagat ataatatcct caagtatttt
     9661 ttcttctctt gcttcttttg ctcttttatg actttccttt acccaaaaat ccaagtctgc
     9721 tttctcaatt tgatatagct ctgctactct ttccgcccct tcgagcatac tattttggct
     9781 attatcatca ggagaaaatt gagcaactgt ataatttgga ttatttgtat catatcgctt
     9841 atcattctta tgatatgtgc gcattggttg tagagaacta ctttcaaaac cacctgcaat
     9901 aattaaatca cactgaccag atttaacctt tgaaaaagct atgtctatac tcatcatagc
     9961 agaagcacac tgcatatcca cagtaaaagc aggtacttca tttgacactc ctgctgttaa
    10021 agtcattaat ctagctatat tccctcctgt cccaactgca tttccacata taatctcatc
    10081 aattttgtca atttcatact ttttaattaa atcttttaaa acacttgctc ctagtaattc
    10141 aggttgaaca aattgaaaaa ttccattttt tagacctata tgacttctca atcctcctaa
    10201 tataaaaact tccttcatac attacaccct tccttatatt atagatttat catagatttc
    10261 ttctgagtac attgttcagt ttagtgccta aaaaagatgc aataactgac tttattgtat
    10321 ctccaattaa aaatggtact actgctgcaa aaagtgctgc ttctactgtc atttgattaa
    10381 aatagcacat aaatactgtt cccataaaat atataatagg cattccaaca aaaattgtta
    10441 ttagtatata tctcttaata tcattgtttc gtccttttaa taaactaata attagtgctg
    10501 caaacaaaaa cccaaaataa aaaccacctg ttgggcttaa caactttcca ataccagatg
    10561 tacctccacc aaatactgga atcccaatta aacctatcat tatatataca ccaactgtac
    10621 taaatgcttg tcttggtgtt aaaattaaag ctattaaatt tatcattatt gtttgtgctg
    10681 ttactcctgc tggagtaaat ggcaatggta tatatatgta agatgatata cacaataatg
    10741 ctacacatat tgacatttta gttaaatctt gaatatttac tttagtattt ttcattttta
    10801 taattccctt catatgtctt atttcattta gtttatatgt acatatacaa agcttctatt
    10861 aaagctttgt tttagtataa aataaagacg tttttttgtc aactattata attatttagg
    10921 tttacattta atttataagt aaactttata ctgttacttt atattttaat agtcatttat
    10981 aaaactttgc ttaaaaacag ctctatttag actatacttg taaattataa tatgatatat
    11041 ttttatataa gattttattt tatataaaaa atagtaacaa atagtttata cacaagatat
    11101 ttaaaaggaa gtgatgatat gaaagttaat gaaaataata taaataatat agatgaagag
    11161 ttagatgaac ttagtaggaa agtttactta gagtccccag atttttggat aagtatttct
    11221 gacaaaataa tagataaagt atttgatgaa atgttattat tttttgcagt taaatataac
    11281 tatttcaata tagtatgctt tgctattgaa aacaattatc tggatttaaa catgccttca
    11341 aaaaacaaaa aatacactaa tataatggag catttgttag atacatcaac gcagaatgaa
    11401 gataaaaaaa tttataatta tcttctaagc ttaaataaag gttatagact agatgaaaga
    11461 ccaattttag atgaattaaa ctgtaatatt agtagtgata cttttgaaaa aaaagatata
    11521 tatcttccaa agtacttatg tccaagttgt aattctaata tatttgatac aggttataaa
    11581 gtatcaaatg acataacata taaattttct tctaaagaag ctgaacctat tgaaatgtgt
    11641 agtgaagttt cttctatcag atgttgtaat tgtgatgaat tattagaaga tattacactt
    11701 gataaactat ataacttatg caaaattcaa aactgtaata attgtggttc taatttaact
    11761 aaggtaggaa ttattgcaaa gaaaaaaatg aactttgatg agaatactga aaaatttaaa
    11821 gatgtctcaa catcttactg ttgtggaaat tgtgactctg aaataaactt atctcaaaga
    11881 gaacatttta agatttaaat atttataggc taaagtaata agattacatt attagatact
    11941 gtataagttt tttaaatctg taaaaataaa tacacttata agaattaaaa ttgctatgaa
    12001 actagttctt gatgaactaa tttcatggca attttctata atctaataat tattaaattt
    12061 taacaaacct ttattagcat tccataatta tttaaaattc tttcaaatac cctatagttt
    12121 ataggtgaaa gtatctttaa tattatatca aacttattat ctttaaatag taaatttgtt
    12181 aaatctgaaa tacaccatac aattttattt tcctcttttg tagctatatc aattctgatt
    12241 aacttacatc tataataaat atctttatct tcatatagtc tattttaaaa attactctta
    12301 aaaaatcaaa tggcaaataa attaattatc cttttaatag aatgtaatca tattatttac
    12361 tatattccat tatgtactct ttaaatcctg aatcttcatt tacttgttct tttactatat
    12421 taaaaccttt tttattataa aacacaactg cttttttatt atctttatat actgctaagc
    12481 ttagactttt atatttttta gttgcataat ctaaaagttt acctccgata cctagatttt
    12541 ggtatttggg ctttataaat aaagctccta taaagctttt atctattatg cttataaatc
    12601 cttttatttc atctccatca tcatatacaa atgtatctga tataggtata tattcgtttt
    12661 taacagtatt atagttattt tgccagtatt ctttacttat aaagtcatgt gctttgattg
    12721 tacttttttc ccatatttcc atgattttat ttatgtcttt attatttaat ttctttatca
    12781 taaattttgt ttcacctcat ttttgtattg attttataat gtttgtaggt aagtgtattt
    12841 tatttagata tgatttagtt aatataaggt ggatgtttta gtatatgcta ttgttgattc
    12901 tacaatttta tatactgctt tattaatata aaataagttt ctaaatactc gttgatattg
    12961 ctaatattct acttatctac cacttagttg atataaaaat tggaacttca ctatctaata
    13021 atttaattaa tgatatgcta ctacatttat ctatttcata accaccataa atcccaggtg
    13081 ttgaatttat aaatatacca gcttgctcta aatacatctt gtaacttttt atttgccttt
    13141 cacttacttc caactcttct gataattctt tgcatttcat tttgcctctg ctttgaatta
    13201 atatcatcat tctaagtgta ttagctaatt tactaatgag taaccccccc taataacatt
    13261 aattgatatt tttattattt atttctacac atatgtacat ataacctctt tatattttat
    13321 ataagtagaa tttttttata attttgacat ttaccatatt atattttata tttgtacaaa
    13381 attttaatag ttaatacaat aaaaaatatt actgaaaaaa taaacatcta taattccagt
    13441 aatattaatt aattttaaac cctttttatt atcatttaat aatagtaact aaaaattgac
    13501 taaatttaac cttatctctt ttaaataatt atttcttaca attaaaaaat aaactatttg
    13561 aaccaagaac aagcttccca ttaccaaaac agctgatgat gctacttcta tatcaaaaga
    13621 atttttcagt gcagtaagtg caaatattga atgtataaca gccactacat aaggaaacaa
    13681 aaatactatt ccaatctcaa ttgttgaagc ttttttaatc tcattatatg tcatacccaa
    13741 tttatttaac tgttcatact ttttcttatc aacttggcaa tccatataaa atttattata
    13801 taaaaaacta cttgtagtaa caaagaaaat taaacctata aatattgcta aaaatataaa
    13861 tgtagaatac attaatttcc cagttcctat cattaattct ttagagaaaa acaaatatgg
    13921 ttgcatccct gactcattat taaatttatt ttcaaattct ctgcatatct ctatagtttt
    13981 acttgaatcc tctacttcaa atgcagtaaa tctatccact ataaattttg attctatact
    14041 atcataaaaa ttatccttta ccacatacat atttttgtaa tatgctggca taacacattc
    14101 ttccacttgt tttgccacct ttaaacctct attccctaca ataatatttt ctttgacgtt
    14161 attatttcct ggtaaacttg atgataataa tgatatacat tcattatctt caaaacttat
    14221 aggcttaacc cctatagttt ctgtaatttc taagtactta gattctttca taattctgac
    14281 attaaaatca cttttcttgg gaaatacagt tttaaattca ccattagtcc ttgtatagtc
    14341 tacattctct ttttttagat tattttctat aaacatcatt ctttccttgt ctttttcttt
    14401 gctatcaggc tttttagggt cattatgcaa tgtcattgtt gaataatata ttgtgttagg
    14461 atatattaaa ttaatttgac gctctacatc tttccaaaag gaataaactg tacctatagc
    14521 agtaaatgcc actgcagaag ttatagttat caagaaaaat attctagcat tatcctttac
    14581 cttataaatc aagttcgaaa tccaaagcat atttgtattt tttctataaa atctcttgtt
    14641 tagttttagc ttcttcataa aaaatacact aaattgagaa aagaacaagt aagttgctac
    14701 tatagtaagg gatgtaactg gaactaagcg cagatatgtt gtatattggt cggttgaggt
    14761 aatagcatta taatacgcta ttataaacaa acaaatactt aatatagcaa gcattagtga
    14821 tgttttaggc tctggttttg gagtttttgt acctttaagt aacttcaaca cctgattttc
    14881 tttaactata aaagaagtaa atattgatgt taatacagct aaaatcataa aatagattaa
    14941 agtagacaat atcgcattaa atggtatata gaattttaat ggtgataatt ctaaaaaagt
    15001 agacataatc actaaaaata tctttgcaaa gattaagcct attattattc caattacaga
    15061 agatactata tttattatca tattttctat aaagattaat ttcattactt ggcgctttga
    15121 tatacctgta atataaagta ttccaaattc tttatatcta cttttaagaa acacactaac
    15181 tgaataaaac acaaagaaga ataagaatag atatgcaatt atcttactca tcttgagacc
    15241 ttcttttaaa taatcaggaa attgagatac atctaaatct ggatgacttg taaacataat
    15301 aaaagaaaat agcagtgaag atgatataac aatacttgct aagtatccta aatacgcttt
    15361 aatatttctt gaaatattgt taatagcaaa ctgttttata ttcattagtt atcgcctccc
    15421 aataatgtaa gtacatccat tatctcttga taaaactgct ctctactact acccttatat
    15481 atttcattat atatagatcc atcttttatg aataagattc tactacagta gctcgctgct
    15541 aatgggtcat gagttaccat catagtagta actttatttt ctttatttat cttttgaaat
    15601 agctccatta caacctttga tgactttgaa tctaaattac ctgttggttc atctgctaaa
    15661 agtattgatg gattgttaat caatgctcta gcaatagcag tcctctgagc ttgaccacct
    15721 gatacttcaa aagttctttt tcctaataaa tcttttatac ctaatattgt agatacttca
    15781 ttcaatctct catcttgctc ttttacactg accttatcta atgtcaatgg caatactata
    15841 ttttctccta tagtcaatgt atccaataaa ttaaaatcct gaaatacaaa acctaactct
    15901 cttcttctaa ataatgcaag ttcctcacct cttaacaata aaggattctt gccctttaat
    15961 tccatagttc ctgtagttgg cttgtcaata gtagaaatca tatttaaaag agtagttttt
    16021 ccactaccag atggacccat aattcctaca aattctccat cttctatact aaaatttatg
    16081 tcatttaatg cgttgaaaat tattttttta ccatatactt tacttaaatt atttacagtt
    16141 aaaattttca ttatttaact atccttccta atttaatttt tgaaataaca tatatataat
    16201 tgttaattat aatttatctt agtttaattt ttatagataa taaatctatt ttttctatac
    16261 actaattatg ttagtaaaag ctaatactgc aagtactaca cccatgatta ttctgtatac
    16321 agcaaacact ctcattgatt ttttctttaa aaaattcacg aatttttcca taactattat
    16381 tgatacaata aaagctacta taaacccaac taccaaagca atccacaatg ttggtgtcat
    16441 tattgaataa tcaaattcaa ataaatcttt tcctgaagaa gccaccatag ctggtactgc
    16501 taaaaagaaa gaaaactcag ctgctgtagg agaattaagt cctgctatcc atccacccat
    16561 aatagtagat gcactccttg acatacctgg ccatgcagac aaaacttgta atgtcccaac
    16621 ctttaaagct tgtattggag taattttatc tatattatct gtagaaggat tcttttttct
    16681 aaacaaagtt tctactacta ataataaaat cccacccact ataaatccta taattacaga
    16741 ttgtaaatta aacaatgatt ttatattatc gtaaaataga actcctataa tcgcaaatgg
    16801 tatacaacct ataattacat tcattccaaa tctaaaacca atctttcctt cttttccacc
    16861 agtaaatata aatttaaaaa attctataac gctatctttt atctttttcc aataaagtac
    16921 tactactgct aatatagccc caagttgtat tacaacctca aacatttcag caaattgccc
    16981 cttaaaatct attaaattac caaccaaaat catatgacct gtagatgaaa ctggaataaa
    17041 ttctgtaagc ccctctacta tagctattat gactgatttc aatataaaaa taacatctaa
    17101 actcatcaat aaacatcctt ccttttttac aaaatttctt tttttatgtt atttctctta
    17161 tgttatttct tatattaatt gtaatttaga ttagaaaatt taactatctg caaacattac
    17221 acaaacctta catctatgta aggtttgcaa ataaactctc ttaaattttg attatttaac
    17281 tatgaatatt tcatttaata aattgtataa taaaaaagta caattaacta aaaaccctat
    17341 tgtaacagat aatttacacc tttattaaac tatttacatc tttattaaag tagattgaaa
    17401 cttctgtacc ttttcctact tctgatttta tacttacttt atgacctaaa tcatcacata
    17461 ccttttttac tagataaaga cccatacctg tagattctcc aaacttacga ccattttctc
    17521 ctgtaaaaaa tgggtcaaat acccttttta aatctttaga aacaattcca attccttcat
    17581 ctattatact taaaattaca tatttattat tttcttcaga ttttatagtt aggtagttac
    17641 tataatcttt agaatatttc actccatttg taattaattg acctattata aatttcatcc
    17701 attttacatc tgtataaaca taagtaaatt tgtctacttg aatcttagga atcattccac
    17761 tttttataaa taaccttttt tcttcattta caatactaga tacaatttca tttaatttgg
    17821 ctttttcaac tataaagtct ttctgaaaat tatctgccct tgcaaaatgc atagccatat
    17881 ctaacccttt atttaatcta tctatttctt ttcttatatt ttcagttact tcttctccct
    17941 cataatcttg aagctgaagg cttataactg atattggtgt tttcatctga tgaatccatt
    18001 ggttgatgaa agttaaatgt tcactatgta tctttttatg ctcttgtatc attgattgat
    18061 acaatttatg ttgttgtttt aaaataactg atatatttct ccccaagaat gagcttccta
    18121 aatacaaaaa tgactcctcc aaagaatgta ctcctttttc aaacagatta tatacttctc
    18181 tatttttata atacttatat attaaaaaac ataacaatat aaaagaacta aataaaagaa
    18241 tatataaact ctctccaaaa ctaataaact tcataagatt acagtaaata attgtcataa
    18301 ctatgcctat ataatatata aaaatataac ctttataatc ttttaaaaat aacttcatac
    18361 tttctcctta ccaattctta tttaatttat atcctaaccc tcggacagtc tgaacagcat
    18421 tatctatacc taattcctca aatcttttcc ttatcctgct aacatttaca tttaaagtat
    18481 tttcctctac aaactcaata tcatcccata tcttttctaa aagataatct ctacttacta
    18541 cttttgggta tctcttgata agacattcaa tcagtatacc ttctttttta gttataatta
    18601 gattctcacc atttaattct agttctaacc tttctggata aaactttaat ccatctagct
    18661 ccactattct ttcgtctatt ttaggtgaat attcaccata tacccttctt atatgactct
    18721 ttatttttgc cattactaca tcatagtaaa aaggttttgt tatataatca tctgctccac
    18781 tttctaaagc tctaatttgg tctacattac catctctagc tgatataaaa attataggta
    18841 aattcgactg ttgcctaata catctacacc agtagaaacc atcaaattta ggtaaattta
    18901 catctaatag aactaagtgt ggcttaaaac tttcaaatgt aatcattata tcatcaaagt
    18961 tctcttcaac aatcacttca aatccatatt tctcaatata atctttaagt aatgtactta
    19021 ttgatatatc atcttccaca atatatactt tataactcat ataattcctc ctaatatacc
    19081 tatttactca tcatataaca gtccaatttt aatatattat aatcttttta caatatataa
    19141 atttaatcat attactaact tcacaattac tgacttcata agtataacca tattattata
    19201 catcttaata aaactctata aaaaagtatc tttttatgat taattaatca ttattatcaa
    19261 ctaatcattc taaaataaat tgaaattact aattcaaaat agaaaaagtt accttaataa
    19321 ggtaacttaa acttttatta tatttcttac ttagtattat tttatcatag tttctactta
    19381 gcattataga ttaattcttt tatgttcact tttttctctt gtaacttatt ttttattaag
    19441 aagtcttgtg tatcttcaag cgaagatatg tctttatctg ttatatctaa actaaaatca
    19501 taccaagcat ataattcttt agtttcttca agacttaaat caacttcttt agctactttt
    19561 tccatagctt catcaaaatt attatttaca tattctaaag tttccttttc aaccttcata
    19621 aatctttcaa ctatttctgg atgtttctct gcaaagtctg tgctaacagc agttactatt
    19681 ataccatcta ctaaaccttc accatttgct acaagtttac tacctgactt catagcttta
    19741 agagctgctg gaccagcaat caatgcagca tctacgctgc catcagaaag agctgctgat
    19801 gcctctggaa tacccatatt aacaaattcc acatcatcca tacttaatcc ttctttatca
    19861 agtgctgaaa taaatacctg atgtaatata gtcccttttg ggcctgccac cttcttacct
    19921 actaaatctg ctgctgattt tattgaatta ttattagtca aaatcataaa tccttttggt
    19981 gacctgctat aagtgtttaa tatctttaac tctactccat tagatgcagc tattaaagct
    20041 gatgtaccac ctagtgcatg taagaagtct atttctccag cagctaaagc ttgtgtttgc
    20101 tctggacctg tagtaatttc gtggaagtta acttttatat tatccttttt aaattccttt
    20161 ccaaataaat catcctgttt ctgaattata gaaggaacat ttaatggtga ctttacataa
    20221 gttaaattta tttctgaaag tttttctcca ttattttttt tagcacatcc agctaaagat
    20281 gctgttgcaa gtgttaatat cgttatacct atcaatagct tttttaattt catttacttt
    20341 actccttaaa atattattaa tttctttaaa tgcctttatt tgatttcatt gtcattaaaa
    20401 tatctttttt taatttaata tagtaatctg aagttaaatc tctattataa ccatcttcta
    20461 tattaaattc ttttattttt ctttcgtctg tgaaaacaac tattttcttg cctatcttta
    20521 acgcttcatc aatatcatga gttacaaata tcacgccttt attagttgac ttatgtattc
    20581 ttataacttc attttgcata tcaatccttg taaaataatc taatgccgaa aaaggctcgt
    20641 ccataagcaa catatctgga ttgaaagaaa gagctctagc tatgcttact ctctgtgcca
    20701 tacctcctga caattcattt ggataagagt ttttaaattt ctgcaagttc atcatcttaa
    20761 gatatttttc tacatcaata ttacttttcc tattatattt atttgatttg ttcaaattat
    20821 catttgtttc taagcttcta aaattatcat ttataatttt actgctaatt cttttattgt
    20881 gtttaaattt tctaagtacc ttgtttaaaa tagtattttt tctttgatta tgaaaagcta
    20941 tattttcact tacgtttaac caaggcatta atctgctctc ctgaaaaaca aaaccaacat
    21001 taggtctata ctctttatta tcattaataa acctaatttc accactattt ataccttcaa
    21061 gtgatgcaat tgctctaagc aaggtagtct ttccacaacc actttcacct aaaattactg
    21121 ttatatggtt tctatctatg tttaaagaga tatcactaag aactacatgt tcttcattgt
    21181 caactttata acttttatat aaatttctaa ttatatatcc agagtcacat actaaattat
    21241 tcatatgctt ccaccatctt tcccttactt accttcttca caataatcga aaatatgtaa
    21301 tctgtaatta ttcctaaaag tccaattacg attataccta caataacaac atctgttcta
    21361 gacatttctt ttccatcaga tatcaagtat ccaagaccag atgaagctgc tacaagttct
    21421 gccccaataa ttgctctaaa gctatatcca agagctaact ttaacccaac agcaatatca
    21481 agaatggcat ttggtattat tattttaaat attatctgaa gctttgaaaa ctcaaatact
    21541 ctacccactt caatcagttt tgagtcacaa tttttaatcc ctttcaatgt gcttgtaaag
    21601 attgggaaaa aggatgctaa aactataatt ataatttttg attcctctcc tataccaaac
    21661 cataatataa gcattggtat taaagcaagg ggaggtgtat tccttaaaaa atttattaga
    21721 gatttaaagt attcgtatac tccactataa attccaaaga atatccctaa aggcacacct
    21781 atagcagtac ttattgcaaa acctatcaaa actcttttca tacttgcata tacattaata
    21841 aatattgaac catcacttat catatttaaa aatgtactat ataccttttc aggtgatggt
    21901 aatatataat cactccaaat accaagataa tttgtaattt tccataataa aagaattata
    21961 aaaaatatca gaacactctt tactagcctt aaaaacttat tattaaattt attgaccatt
    22021 tacaaaccat ctccattatt acaaccatct ttacaataaa acatttctac tatgtcatac
    22081 ttatcttcaa agccatttct tattttttgt atttcactta atatttcgtc ttcacttgat
    22141 acttcaagaa ctttttcaaa agtatctttg aaatatccta atggaattgg tgattcatct
    22201 atttttccaa gtgattttac accttcttgt tcagcaaact ctttccatgt ataaaacata
    22261 gcattaccct tatccttaaa cgtttcactt gcaaagtctc ttaattgtgt acatgggcag
    22321 gttactacca acatatcatc tttacttttt atatatttat cgtataaaac cctacaagtc
    22381 cttactaata ttggttctat cataggtact tcaaaatcat ttatcaaatt atttcttttt
    22441 aaaagactta tactttctgg acatctacaa tccaacattg tattttcagt cttttttgta
    22501 tactctttgt actgcttttt tacatattct aactgtggtt cacattctgc tattatgtac
    22561 ccctttttta tcaaatttgc tttaataagg tgaaactttt ctccatacat tctttctgcc
    22621 actggattta ttagaagata tttattcata acgcctccta ttatttaata ttgaatatta
    22681 ttatcaatta atagtttaaa tgagcactta aattttgtca atatattaat tttttcttaa
    22741 taaaacaatt tttatctaca ttttttaata ttttaaatga aatattaaat agtatatgta
    22801 atttatttta attaataat
//
LOCUS       DAEORM030000058        22333 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.058, whole genome shotgun sequence.
ACCESSION   DAEORM030000058 DAEORM030000000
VERSION     DAEORM030000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 22333)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22333)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 22333)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22333
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.058"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            <1..897
                     /locus_tag="KRH23_002994"
     CDS             <1..897
                     /locus_tag="KRH23_002994"
                     /inference="COORDINATES: protein motif:HMM:NF013909.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HHS5226271.1"
                     /translation="VVIQYYYKGVVIIKAIELYKKLDLEFNIKNINDDWSFMNFENDF
                     ITPEFRKKYIGLVLDNAQNINKVYTTTFPDKEIIKQVIDKDEKDILIFSHHAMGYIAS
                     DEGFPFHDIPLSYMEEMKNRRISFYVLHSPLDNYSDYSTSVSFAKAMGLEIVKPFCKY
                     DDKIEVGVICKTSLKSIEEIKELIKKSVGHDVKLYDYGDSVLKDGLVAIAAGGGSYPF
                     VAREVAELGINLYITGFTKPLKHFEPVLEFHQIAKDNLINVIGATHYSTEKFACMGMV
                     DYFKNLGLESEFLQGKYYLEDL"
     gene            1772..2479
                     /locus_tag="KRH23_002995"
     CDS             1772..2479
                     /locus_tag="KRH23_002995"
                     /EC_number="2.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase"
                     /protein_id="HHS5226272.1"
                     /translation="MIFTKSNKYDKDFLMKNMMGPNCIKILEELTSKIKLEKGMRILD
                     LGCGKGISSIFLAKEFDATVFATDLWIEPTENYKRFKEFKLDDKIFPIQAEAHELPYA
                     EGFFDAVISIDSYHYFGNKEGFLDNHISPLVKEGGILAMAMPGLKEDFVDCIPDELIP
                     FWQDNMNFHSITWWNKLWSESESVIVEKCEALNCHDEAWKDWINCDNSYAINDKKMME
                     VENGKYFNTISLIARTK"
     gene            3091..3591
                     /locus_tag="KRH23_002996"
     CDS             3091..3591
                     /locus_tag="KRH23_002996"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HHS5226273.1"
                     /translation="MIEGIKFIKAEEKYIYSYWQTFDKIAKERKYLAMDEAFPFEETV
                     EFIKNTINKNLPQLFIIDLESDNCIGWCDVLPKTEKVGYLGMGILKEYREKGIGSSLL
                     KQIIDLSKEYGYEKIELDVFKSNSRAIHVYKSLGFVEVNTISSGFTWNDRPVKEEVIQ
                     MELTLI"
     gene            complement(3841..4620)
                     /locus_tag="KRH23_002997"
     CDS             complement(3841..4620)
                     /locus_tag="KRH23_002997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226274.1"
                     /translation="MNKNILNNSFPEVPESFHNSLSKTLNSLPEREENYKMINNKTHK
                     LPFRKGLVATLAITLILSTTALAVGHIYSLVGKSSTKATYTSIPTTEQVKKDFNFTPN
                     IVSEFSNGYKFKGAYTVNKKAFDKENNVLGKSKTLSFEYKNGNDEISLDTANNVLGKS
                     SDNLKVVDTYKDINISYEAFAQKFVPEGYKMTEQDKIDEKSGKYTFSVGPNNESDKVE
                     VNKFKFLTWKQDEVYYSFTVQDSNLSMNDLVKMAHEVIDAK"
     gene            complement(4617..5096)
                     /locus_tag="KRH23_002998"
     CDS             complement(4617..5096)
                     /locus_tag="KRH23_002998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HHS5226275.1"
                     /translation="MDKTTFTNNILESEQTLYRVSKSILGNDQDCEDAVNNAILKAYE
                     KLDSLKEEQYFKTWLIRIVINECNSLRRKRLKSLSFEDVFKNKKIDEKDDYSDLYTAI
                     QSLPKKIKIPIVLYYIEGYSVDEVKEILDIPQGTVKSRLSRGRRLLKTKLENTEVII"
     gene            5598..5885
                     /locus_tag="KRH23_002999"
     CDS             5598..5885
                     /locus_tag="KRH23_002999"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226276.1"
                     /translation="MKKKNSFDERFYQIATETGLSANTVYKVFNKIINSGKTEFTSKE
                     LATICGVSIRTMDRIILRLCDSGYCEVVSEQLMSKYGRPSRILRFKPFLLF"
     gene            6082..7089
                     /locus_tag="KRH23_003000"
     CDS             6082..7089
                     /locus_tag="KRH23_003000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HHS5226277.1"
                     /translation="MGKYQDSKKVVRNYFEALENATGDEVENVLKQHMKSDYNWKGVY
                     PFREQEGTENVADVFWKPLKKSLSNMQRRQDIFIAGTNEIDNSEWVMSMGHFMGLFDN
                     DWLGIKHTRKMISLRYAEFNCVQDGKIAKTGLFVDIIGFMIQAGVNPLPPQTGSYFVY
                     PGPIDHNGLLFEDADEVEGVKTLALVNKMVDDLSELNESGAMGCPPEILEKSWAKDMI
                     WYGPGGIGASYTIPRYQEQHQLPFRNNLKGKTFNGHVCRFAEGNFACFFGWPNLTNVP
                     CGGFLGLPGGEVKADMQVVDVYYRKGDKLQENWVLIDIPYWLKQQGLDILERTKSIFN
                     A"
     gene            7127..8539
                     /locus_tag="KRH23_003001"
     CDS             7127..8539
                     /locus_tag="KRH23_003001"
                     /EC_number="5.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0030638 - polyketide metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ester cyclase"
                     /protein_id="HHS5226278.1"
                     /translation="MASTNKNNATSKEEEKEVSTSGLESCTVKENKAKMNQTNFSNIN
                     ENQTNENKTNTYKRNIDKGNIDKTNTNKSDINKVNIDTVDTDKLNTNTLTEKNKKVIF
                     KGEDNMSSTKIYYGDSLEVTPVGVMDYNDFSKQTKREQEIPGFDSKYRDFVDYIMKIT
                     HNIWEEKGIGVIYDTYHNNVTMHCGSSNLVGIKDVISNTLQTLHAFPDRRLIGQNVIW
                     SNFGADGFLSSHRVLSTATNLGDSNFGPATGRKINFRTVIDCATTNNRIHEEWLVRDN
                     LWIVTQLGLNPQEVAKSMAKASESKVLSLQSTYGICESMDGQFMPTKYQAKDDSVGEM
                     MLEMTSRIYNYKYINEVKKYYHDNAVVHFICDKDLNGYDEIQGMIVSLLASIPNGSYE
                     VERVTCNQREKNEGYDVSVRWRLRGINEGIGFFGQPSGKHIEVMGINHYHILQGKVKE
                     EWITFDGMDVLKQMYMGVEE"
     gene            8683..9948
                     /locus_tag="KRH23_003002"
     CDS             8683..9948
                     /locus_tag="KRH23_003002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HHS5226279.1"
                     /translation="MKTTVEIENDIILGKDYSNLKRGIAFFSIALIYFFYCYNFMVGT
                     FIKPTMIYALADGGFGFSLKQTEEIFAVMSFGTIPGTFIFGVISTKIGKKRTLISVAL
                     LIGLTTFIPMLSPTNIMLWKIARLCTGVVLGGVFGTAMPLVADMFPSKYRGKLAAILT
                     ALFSLAMIFGGKVYGVLGDANWQILMYTAIIPPIVGAILAIFFVPDDLEYTKELVKKG
                     KETGEKISYISMYKGKYLWIGLGTILLSGANFTAYSAFSNNATTYLVTGIGMSAAVAG
                     SIYSLQGIGQLVGYLFWGSIADKFGRKIPFIGMALAAVFVFIYTKLGGDNTTTFYMIS
                     VLLGVAVGYSGAWGAYYTELFPSKYRSLSSGMSFNGGRIISTFAIPAIAGTASGTLGM
                     MTIFYISIAVFVAGAIVWLFLPETLNNKK"
     gene            9990..11588
                     /locus_tag="KRH23_003003"
     CDS             9990..11588
                     /locus_tag="KRH23_003003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter"
                     /protein_id="HHS5226280.1"
                     /translation="MISSIDVCIIIGYLLLMLVIGYYSGKDNKNQEDYFLAGRSMPWI
                     PIALSVAATMISANGFIGGPGWAYVDGMYPVMVNITVPLAIFFALSITTPVIYKLKIT
                     SIYEYMGLRLGNYSRGLTIIQFFINSLIQASSMVYIPVLIIQMITGWSLYALVPIVVL
                     VSIIYTLLGGIKAVIWTDSIQMIVVISAVFIVIIVALKGMNLSFFDTLQIAQQSGKLN
                     TFDFSRDISVTNTFWATLIGGTVMWIRYFCFDQSQVQRVLTSKSLKCAKNSFVVSAFV
                     MNLVYYFMLLVGVILFVFYGGRTFETSNEIMITFILNELPVGAIGIIIAGVFAAAMSS
                     IDSILNSMTTVFTKDIYEFYFKKDNKESSLKVTMIITVVIGVVMTGFIIMGFGGSIKS
                     ILDLVGNYISYFAGPATGAFVLAMFTYKANDKGVSIGFIVGLVLGFFISNKYNVSWLW
                     NPAIGATITLIFGYIFSVILKKNHNADDIKKYTAFGMRNHLISQGMDKVDGVSIVPFS
                     LGKQELIVLAFFIIQYIILFLIQF"
     gene            11623..12645
                     /locus_tag="KRH23_003004"
     CDS             11623..12645
                     /locus_tag="KRH23_003004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HHS5226281.1"
                     /translation="MNQKKVHYNKSATSKDVARLAGVSQSSVSRAFGSANGKGVKPEV
                     RERIFRVANEIGYVPNLVARGMISGKTNVIGLIVGDSLGPFYNRIINLFVEKIQEIGK
                     QCLVFKVPRQQSIDSIISKVIQFQVEAVIITASAMNKVMAETCEENNIPVILFNRFIP
                     GIKISTVYVDPIEGGGMAAEYLLKKGHKNIGYIQFTRETSEEMEKKIGFYSKLRQSGI
                     HNLKEESANYDYDSGYEAGKRMLALSNPPTAIFCTSDLIAIGVMDAARFEYKLRVPED
                     LSVIGYDDIQMASWKSYNLTTIRQPLDLLIEKTINILKSLLNEENPESVVEMLKPELI
                     ERGSTL"
     gene            complement(13046..14449)
                     /locus_tag="KRH23_003005"
     CDS             complement(13046..14449)
                     /locus_tag="KRH23_003005"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004176 - ATP-dependent peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0030163 - protein catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent metallopeptidase FtsH/Yme1/Tma
                     family protein"
                     /protein_id="HHS5226282.1"
                     /translation="MKMLNNFFKKINNPAPVFAQTKMERDNQTDDSLSTKPKTTFRDV
                     AGLDEVKEELFEIVDFMKSPQKYQKMGAKIPKGVLFYGPPGTGKTLLASAVAGETNSS
                     FFNVTGSEFVEKYVGVGAKRVRTLFEKARKEAPSIIFIDEIDAVGAKRHLESNNEKDQ
                     TLNQLLVEMDGFNKDSNVLIIGATNRLDLLDEALLRPGRFDRHIHIGAPNYHTRFEIL
                     KVHTDDKPIDKSVNLELLAKKTHGFNGAHLSNIANEAAIFAVRDDSECITSEHFDKAL
                     ERVIAGLESKNSALVEKEKKIVAYHEAGHALVSDIVGICPIQKISIVPRGQALGYVLQ
                     LPDEDRYIYTKDELIGKIKILLAGKASEELIFNHKSTGAKDDLKKVTEIANQMVCEYG
                     MSNLGFMTIDGNDKTFLCDKVQKEANRIVEICYKETLEMLKDNLEDLHSVSKFLFEKE
                     TMTHEELKDLIGKEAVN"
     gene            15428..15919
                     /gene="infC"
                     /locus_tag="KRH23_003006"
     CDS             15428..15919
                     /gene="infC"
                     /locus_tag="KRH23_003006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009528606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HHS5226283.1"
                     /translation="MNEQIKDKEIRVLSPTGEQLGVMPTKEAQAMANSKNLDLVQISP
                     NANPPVCKIMDYGKFRYEQARKEKEAKKKQKTIVVKEVRLRPGIEQNDLNTKANNAIK
                     FLKKGDKVKVELRFRGRELGHKDIGKEVMLKFLDIIKEFGEPTKAPAFEGNNMVVIID
                     PKK"
     gene            15947..16141
                     /gene="rpmI"
                     /locus_tag="KRH23_003007"
     CDS             15947..16141
                     /gene="rpmI"
                     /locus_tag="KRH23_003007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HHS5226284.1"
                     /translation="MPKMKTHRGAAKRLKKTGTGKLKRAKAFKKHILTKKSAKTKMNL
                     RKSTLVSDGDAKRIAQLLPY"
     gene            16197..16553
                     /gene="rplT"
                     /locus_tag="KRH23_003008"
     CDS             16197..16553
                     /gene="rplT"
                     /locus_tag="KRH23_003008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HHS5226285.1"
                     /translation="MARVKKAMNARKKHKKILKLAKGFRGSRSKLYRPANTFVMKALK
                     NAYIGRKLKKRDFRKLWIQRINAAARMNGISYSRLMNGLKLSGIEVNRKMLSEMAIQD
                     PEGFAKLAEVAKAKLA"
     gene            16863..17408
                     /locus_tag="KRH23_003009"
     CDS             16863..17408
                     /locus_tag="KRH23_003009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226286.1"
                     /translation="MNEKLMDCFVNPIKCKLLLEVFSNNRTTAKQLGEKFQDISKATL
                     YRYLNKMLKDDIIKVVEENKIRGTVEKVYAMKLDIADDVNKIIDENSGEEYAQLFTQY
                     MMGFLREFYEYAERKEKDILKDGSGFSVCPVYASIDEIVEVSKKIASILEPLRNNSHE
                     EGRRMHSIGVIITPPKEDEGK"
     gene            17395..17559
                     /locus_tag="KRH23_003010"
     CDS             17395..17559
                     /locus_tag="KRH23_003010"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226287.1"
                     /translation="MKGNKSDLHGVEPIYTGNRFMIYICIQSKVSLLGLYFIVSFHLF
                     NDLEWYNEVF"
     gene            17848..19773
                     /locus_tag="KRH23_003011"
     CDS             17848..19773
                     /locus_tag="KRH23_003011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HHS5226288.1"
                     /translation="MKIKFVIMPLVIFLMVLFVGCQSTKDTEVKAKDTEIKILGTGDL
                     HSILTDSMVSYVNEEREKNKNLLMVDAGDFYGTQSREMWEWSSGKKLINIKRNGRAEY
                     DDIIKSSKDEVPIVKDMAKLKYDAVVLGDNEFVSNDKQSLDKLVSDFKNNNMPLVSAN
                     IYEQSGENYVQPYVMKNIKTDEGNVKVGILGLTIKEVGETLGLEDFEKDKKARELGEQ
                     ADYKGKLYANDLVEDAKKWIKVMEKESPDIIVAVVHSGEEPKTDRNPGNRIKELATTV
                     DGIDAIVAGHTHEKIDEHKYENKSGDEVIVTQPGWHGDRVSEINFKLNKENGKWDIKE
                     KSSKLKIIDKEVSIVATADLHSHFSDKLTVDLVNERSNPIEPVVVDAGDFLDPQTDEM
                     TQWYKEWKSIRDNNSDKTISRCPMVMDMNQGMYDAVVLGNHEFVSEKDEFWSDERLLD
                     AVIEDFEQVAISVLSANIYRQSGKNYVKPYIIKDVETSEGNVKVGILGLTIKEVGKGL
                     KNVNLQEQFQYKDKLYANDLVEDAKKWVKVMKKKKPDIIVAVVHSGEEPKHPKHPGNR
                     IKELATTVDGIDAIVASHTHEKIDEHEYKNKSGEKVIVTQPGEHGKYYSKITFKVNKE
                     KGSWTINDKFSKTIEVE"
     gene            20174..22078
                     /locus_tag="KRH23_003012"
     CDS             20174..22078
                     /locus_tag="KRH23_003012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HHS5226289.1"
                     /translation="MKIKFIIVASIIFLIVLLVGCQSTKDTEINVLATSDLHSIIPDN
                     LISYVEEERKYDENLLMVDAGDFFDMQSGEMNKWFTGQKLVRFKDGIPEYKKIAEPRE
                     GEVPLAKKMAKLKYDAVTFGNHEFVSNDKQSLDKLVSDFKNNNIPLVSANVYEQSGEN
                     YVKPYVMKNINTDKGTVKVGILGLTIKEVGERSRFKSFEQDKKARELGEQPQYKGKLY
                     ANDLVEDANKWVKVMEKKEKPDIIVAIVHSGEEPKNPKNPGNRIKELATTVEGIDAIV
                     AGHTHEKIEQHTYKNNSGEEVIVTQPGAHGNSISKINFKLDKKNDKWFIKDKYSELKV
                     FGKEVNIITTSGLNPKFSDEMAVNLFNERDRDVQPIFIDTGDFLNTNTKEMTNWAKEW
                     QYNENKGIYKKINELPIVYLGYDAVVLGSHEFKEDKETFEEKKSTLDYIIENFEEMKI
                     PVLSANIYDESGENYVKPYIIHNVETREGNIKVGVLGLTTTDKDEEDLSSSSLSKDSK
                     TSKIPEETGKLYTNNLVKDASEWVKVMQKESPDVIVAVVHSDNNSTLKNPSSEVKKLA
                     MSVDGIDAIVVGHTKNKVEEHIYKNKSGDEVIVTQSGEDCYSKISLELRKENGKWNII
                     NKYSKAIKMK"
BASE COUNT         8516 a         2420 c         3889 g         7508 t
ORIGIN      
        1 gtagtaattc aatattatta taaaggagtg gttattatta aggcaattga actttataaa
       61 aaattagatt tagaatttaa tattaaaaat attaatgatg attggagttt tatgaatttt
      121 gaaaatgatt ttattactcc agaatttaga aaaaaataca taggattagt attagataat
      181 gctcaaaata ttaataaagt atacacaact acttttcctg ataaagaaat aattaagcaa
      241 gttatagata aagatgaaaa agatatttta attttttcac atcatgcaat gggatacata
      301 gcatcagatg aaggttttcc atttcacgac ataccactat cttatatgga agagatgaaa
      361 aatcgtagaa tttcttttta tgtattacat tctccactag acaactatag tgactattca
      421 acttctgtta gttttgcaaa agctatgggt ttagaaatag tcaaaccatt ttgtaaatat
      481 gacgataaaa ttgaggtagg agttatatgt aaaacatcac taaaatcaat agaagagatt
      541 aaggaattaa ttaaaaaatc tgttggtcat gatgtgaaat tgtatgatta tggagattct
      601 gtattaaaag atggtttagt tgctattgca gcagggggag gaagttatcc atttgtagca
      661 agagaagttg ctgaacttgg tataaatcta tatattactg ggtttactaa gcctttaaaa
      721 cattttgaac cagtattaga gttccatcaa atagcaaaag ataatttaat taatgttata
      781 ggtgctactc attattctac agaaaaattt gcgtgtatgg gcatggtcga ttattttaaa
      841 aatctaggtt tagaatcaga atttttgcaa ggaaaatatt acttagagga tttataggac
      901 atattaaaca ataaaaataa acagttagta aaaatttatt ttactaactg tttatttttt
      961 tacctattta tctagtgttt tgaaaaaatc tatctttatt ttttaaacta agaaaataga
     1021 cttttaattg ctgattagaa gatttagttt tgatgtcttt taaattattt ttcgatattt
     1081 tttagtttat tttttgatgt attttagatt attatttacg attgattaga atttataaat
     1141 atttatttta gattattata aatatttatt ttaaaaaaat agaattatta tatttatgat
     1201 aataaatggt ataataaaag gtaaagtgtc aaatatgcac taaattaaat aagttaatta
     1261 gtatataggt taaagtggaa gtaattaaaa cttattaagt attagaaaat gacttcttat
     1321 tagagtaagt atctaaaatg atataaaaat tatgattact cattaaagtg actattatag
     1381 agtggataag attactcatt aaagcgatta ctgtggaata gataaaatta ctcactaaaa
     1441 taactatcat agagtggata agattactca ttaaagcgat tactgtggaa tagataaaat
     1501 tactcactaa aataattatc atagagtaga taagatactc attaaggtga ttattgtaga
     1561 gtagataaaa ttacccatca aagttaacta tcacagtaga taagattatt cattaaagtt
     1621 actatcacag agtggataaa attacacatt aaaattgtct gttagagaat gaataaaaaa
     1681 gagattgctc aatataagaa gcatataaaa aataaaaaat caaacgtata aaatttaata
     1741 aataataact gatagggaaa ggaaagatag aatgatattt acaaaaagta ataaatacga
     1801 taaggacttt ctcatgaaaa atatgatggg acctaattgt ataaaaatat tggaagaatt
     1861 aacaagtaag ataaaactag aaaagggaat gcgtatttta gacttaggtt gtggtaaggg
     1921 tatatcttcg atatttttag caaaggaatt tgatgctact gtatttgcaa cagatttatg
     1981 gatagaacca actgaaaact ataaaagatt taaagagttt aaattggatg ataaaatatt
     2041 tccaatacag gcagaggcac atgaactacc ttatgcagaa ggtttctttg atgcggtgat
     2101 aagtatcgat tcatatcact attttggaaa caaagaagga tttttagaca atcatatatc
     2161 acctcttgta aaagaggggg gaatacttgc tatggcaatg cctggattaa aagaagattt
     2221 cgtggattgt ataccagatg aactcattcc attttggcaa gataatatga acttccattc
     2281 aattacatgg tggaataaac tttggtctga atcggagtct gtgattgtag agaaatgtga
     2341 agctttaaat tgtcatgatg aagcttggaa ggattggata aattgtgata attcatatgc
     2401 tataaatgac aaaaaaatga tggaagtaga gaatggaaag tattttaata caatttcttt
     2461 gatagcgaga actaaataat tgtgatgaat ttataaaagt ataagataag tagaaatata
     2521 agttgaatga gagtataaga agcatagaaa tataagttga attaaagtag aaggtaaata
     2581 aaaatgtaag ttaaataaag agtttataca aaaatgattt tttagattat ttatacccaa
     2641 tcgagttgct taggtcagtt gggtattttt atttttttaa agttaaattg caaatactat
     2701 tatgtgatat atattttaat actaaatgtt tgttttataa gaaataaact aatagaaaaa
     2761 atagttttaa caatgaaagc aaaaaaggta ttgatgaaga ttaaaaattt tatagtacca
     2821 ttttatatat ttttttatat attttattat actttaaatc aaatttcaaa atgattaagt
     2881 atatataccc aaaagattaa agaactatat ttattatact attaaaaatt attttaatag
     2941 agatacaaga gatagatata ttggttttaa ttttatagaa atatacaaag atattttaag
     3001 ctaatatata gtaatttata tagcattata aactagaatc atataaaata agttaactac
     3061 aatcaaaaat taaaaagggg aaatgttaag ttgatagaag gcataaaatt tataaaggca
     3121 gaagaaaagt atatttattc gtattggcaa acttttgata aaatagcaaa agagaggaaa
     3181 tatctagcta tggatgaagc ctttcctttt gaagaaacag ttgaatttat aaaaaatact
     3241 ataaataaaa acttaccaca actgtttata attgatttag aatcagataa ctgtattggt
     3301 tggtgtgacg ttttacctaa aactgaaaaa gttggttatt taggcatggg tattcttaaa
     3361 gagtataggg aaaaaggtat cggaagtagt cttttaaaac aaattattga tttatcaaaa
     3421 gaatatgggt atgaaaaaat tgagcttgat gtatttaaaa gtaatagtag agctattcat
     3481 gtttataaat ctttagggtt tgtagaggta aatacaatat ctagtggttt tacatggaat
     3541 gatagacctg taaaagaaga agtaattcaa atggagctta cacttatata aaataaagtt
     3601 aaagtcttta aaattccata tacacttgta taaaataaag ttaaagccct taaaattcca
     3661 tataaaagaa atatttttaa gggcttttta ataatggttc ttttgaaggt agctaaatat
     3721 ctaaaatttt atatattaaa tttaaagaaa atataaagat ggaagataca accatgttta
     3781 ctaataaaaa aattaaagtc ataaataata aactcataaa cgacttatta ttacttatgt
     3841 ttattttgca tctattactt catgagccat tttaactaag tcattcatag ataaatttga
     3901 gtcttgaact gtaaaagaat agtaaacttc atcttgtttc catgtcaaaa acttaaattt
     3961 attaacttca actttgtctg attcattatt tggccctaca ctaaatgtgt atttgcctga
     4021 tttttcatca attttatcct gttctgtcat tttataacct tctggtacaa acttttgtgc
     4081 gaatgcttca taagaaatat taatatcttt gtaagtatct acaactttta gattgtcaga
     4141 actcttccca agtacattat ttgctgtgtc aagagatatt tcatcattgc catttttata
     4201 ttcaaaacta agtgtttttg attttcctaa aacattattt tctttgtcaa atgctttttt
     4261 atttacagta tatgctcctt taaatttata tccattacta aattcagaaa ctatattagg
     4321 ggtaaagtta aagtcttttt ttacttgttc tgtagttggg atagatgtat aggtagcctt
     4381 agtacttgat tttccaacca aactatatat atgtcctact gcaagggctg ttgtgctcaa
     4441 tatcaaagta atggctaaag ttgcaactaa gccttttcta aatggtaatt tgtgtgtttt
     4501 attattaatc attttataat tttcctctct ttctggtaaa ctatttagtg ttttgcttaa
     4561 actattatga aaactttctg gaacttctgg aaacgaatta tttaatatat ttttattcat
     4621 atgattacct ccgtgttttc taatttagtt tttaataatc ttcttcctct tgataatcta
     4681 ctttttacag ttccttgagg tatatctaat atttccttaa cttcatctac tgaataacct
     4741 tcaatatagt aaaggactat tggaatttta atttttttag gtagactttg aatagcagta
     4801 tacaaatcgc tatagtcatc tttttcatca atttttttgt ttttgaagac atcttcaaat
     4861 gatagagatt ttaatcgttt gcgtcttaat gaattacatt catttatgac tattctaatc
     4921 agccatgttt taaagtattg ttcttcctta agagaatcca acttttcata tgcttttaaa
     4981 atagcattgt tgacggcatc ttcacagtct tggtcgtttc ctagaataga cttagatact
     5041 cgatacaaag tctgttctga ttcaagtata ttgtttgtaa atgtagtttt atccaactaa
     5101 gttccttccc ttctatgcaa atcgtagcgc tacttttttg cctttcactt attagataaa
     5161 attttactat agatggttca ctttttttat gattatttga taaatttaag tttgaaagtt
     5221 ttgcctattc tatacaaata ttctataata tattttttct agtattttcc cctcatatat
     5281 aaagccatgt agatatatta aactttagaa gccatttata tatttagttt tatagtaagt
     5341 ctttatattg agtaattaga aaatagtaag tatttaatgt tgagtagtta gaataacaat
     5401 gcttttggat tatttacttc atgtacagat ttaaaataag ttctttaaat agcaactttt
     5461 tgaaaaaacg caaaaatatt ttatgttgtc tgattatatt tatagatgtg aaacaatatt
     5521 gtatagagta aaagtatata gaagatgatt acatagagtt tatacttgaa ttttacaaat
     5581 ataattatca aaatactgtg aaaaagaaaa atagctttga tgaacgtttt tatcaaattg
     5641 ctacagagac agggctaagt gctaatactg tatataaagt attcaataaa ataataaata
     5701 gtggaaaaac tgaatttaca tcaaaggaat tagctactat atgtggtgta agtattagaa
     5761 ctatggacag gattatactt agattgtgtg attctggtta ttgtgaggta gtgagtgaac
     5821 agcttatgag caagtatggt agacccagta gaatattacg ttttaaacct tttctgttgt
     5881 tttaaataga tataagtcaa aaattaaatt tttatgataa cattttcttt acaatttttt
     5941 agatatatgt taatatttag aaaaatgcat atgtattcat aaaataaact taaaacagct
     6001 aaaaaatcat taaaaaggaa atcgtatgca taaaatgaga aagttaattt ataacttaaa
     6061 taaatctggg aggagataat tatgggaaaa tatcaggatt caaaaaaagt tgtaagaaat
     6121 tattttgaag cattagaaaa tgctactggg gatgaggttg aaaatgtctt aaagcaacat
     6181 atgaaatcag attataactg gaaaggtgtg tatccatttc gtgaacaaga aggcactgaa
     6241 aatgtagcag atgtattttg gaagccttta aaaaaatcat tgagtaatat gcaaagacga
     6301 caagatattt tcattgcagg aacaaatgag attgacaata gtgaatgggt aatgagtatg
     6361 gggcatttta tgggactttt tgataacgat tggcttggca ttaaacatac tcgcaaaatg
     6421 attagtttaa gatatgcaga atttaactgt gttcaagatg gtaaaattgc taaaactgga
     6481 ttatttgtag atataattgg gtttatgatt caagcaggag ttaatccatt gccaccacaa
     6541 acaggttcat attttgtata tccagggcca attgaccata atggattact ttttgaagat
     6601 gcagatgaag ttgaaggagt aaaaacttta gcattagtaa ataaaatggt agatgattta
     6661 tctgaattaa atgaaagtgg tgctatggga tgcccaccag aaatacttga aaaatcttgg
     6721 gctaaagata tgatttggta tggtccaggt ggaattggtg cttcttatac tatacctaga
     6781 tatcaagagc aacaccagct accatttaga aataatttaa aaggaaagac ttttaatggg
     6841 catgtatgta gatttgcaga aggtaatttt gcttgtttct ttggatggcc taatctgact
     6901 aatgtaccat gtggaggttt tttaggatta ccaggtggag aggttaaagc agatatgcaa
     6961 gttgttgatg tttattatcg taagggcgat aaacttcaag aaaactgggt gttaattgat
     7021 attccttatt ggttgaaaca acaagggctt gatattcttg agagaactaa aagtattttt
     7081 aatgcttagt tatgcatacg tattctaaaa caaaggggga tataaagtgg catctaccaa
     7141 caaaaataat gcaacaagta aagaggaaga aaaagaagtt tctacaagtg ggcttgaatc
     7201 atgtacggtt aaagaaaaca aagctaaaat gaatcaaact aattttagta atataaatga
     7261 aaatcaaaca aatgagaata aaacgaacac atataaaaga aatatagata aagggaatat
     7321 agataaaaca aacacaaata aatctgacat aaataaagtt aacatagata cagtggatac
     7381 agataaatta aatacaaata ctcttactga aaaaaataaa aaagttatat ttaaggggga
     7441 agataatatg tcatctacaa aaatttacta tggagattca ttagaagtaa cgcctgttgg
     7501 agtaatggat tacaatgatt tttcaaaaca gacaaaaagg gaacaggaaa tacctggatt
     7561 tgattctaag tatagagatt ttgtagatta tattatgaag attacacata atatctggga
     7621 agaaaaaggt ataggtgtta tttatgatac atatcacaat aatgttacaa tgcattgtgg
     7681 ctcttcaaat ttagttggta ttaaagatgt tatttccaat actcttcaaa cattacatgc
     7741 gtttcctgat agaagattaa ttggtcaaaa tgtaatatgg tctaactttg gtgctgatgg
     7801 ttttttatct tctcaccgtg ttttgtctac agcaactaac ttaggtgata gtaattttgg
     7861 accagcaaca ggtagaaaaa taaactttag aactgtaatt gattgtgcca caactaacaa
     7921 tagaatccat gaagaatggt tggttagaga taatttatgg attgttactc aattaggatt
     7981 aaaccctcag gaagtagcaa agagtatggc aaaggcaagt gaatctaaag tgcttagttt
     8041 acaatcaact tatggtatct gtgaatctat ggatggtcaa tttatgccaa ctaagtatca
     8101 agcaaaagat gattctgttg gcgaaatgat gcttgaaatg acaagccgta tttataatta
     8161 taaatatata aatgaagtta aaaaatacta tcatgataat gcagtagtac attttatatg
     8221 tgataaagat ttaaatggtt atgatgagat tcaaggaatg attgtaagtt tacttgcatc
     8281 aattccaaat ggaagttatg aagtggaaag agtaacttgt aatcaaagag aaaaaaatga
     8341 aggttatgat gtatctgtaa gatggagatt acgtggaata aatgaaggta taggattttt
     8401 tggacagcct tctggaaagc atatagaagt aatgggaatc aatcattatc atatactaca
     8461 aggtaaagta aaggaggagt ggataacttt tgatggtatg gatgtattaa aacaaatgta
     8521 tatgggagta gaagaataaa gctgtttaga gtataaatag ttttgaaata tatataggga
     8581 agtattgctt tataaaattt aagtggggaa tgtatatgaa aaatagatgt ttaaactttt
     8641 agcaaaatta tgactaaatt taaaaggggg aattataaaa atatgaaaac aacggttgaa
     8701 atagaaaatg atatcatatt aggaaaagac tattcaaacc taaaaagagg aattgcattt
     8761 ttttcaattg ctttaatata ctttttttat tgctacaatt ttatggtggg tacttttatt
     8821 aaaccaacaa tgatttatgc tttagcagat gggggatttg gtttttcatt aaaacaaaca
     8881 gaagaaatat ttgcagttat gtcttttggt acaattccag gtacatttat ttttggggtg
     8941 atttctacaa aaattgggaa gaagaggact ttaattagcg ttgctttact gattggattg
     9001 acaacattta taccaatgtt atctcctaca aatattatgt tatggaaaat agcacgtttg
     9061 tgtacaggag tagtgttggg aggcgtattt ggaacagcta tgcctttagt tgcagatatg
     9121 tttccaagta aatatcgtgg taagttagct gctatattaa ctgctttatt ttcattagca
     9181 atgatttttg gtgggaaagt atatggcgtt ttaggtgatg caaattggca aatattgatg
     9241 tatactgcga ttataccacc tatagttgga gctatcttag caattttttt tgtgccagat
     9301 gatttggagt atacaaagga attagttaaa aagggaaaag aaactggtga aaagattagc
     9361 tatataagta tgtataaggg aaaatactta tggattggat tgggaacgat tcttttatca
     9421 ggtgcaaatt tcacagcata ttcagcattt tcaaataatg caactacata cctagtgaca
     9481 ggaataggaa tgtcagcagc agtggctggg tctatatata gtttacaagg aattggtcaa
     9541 ttagtaggat atttattctg gggttcaatt gcagataaat ttggaagaaa aatacctttt
     9601 ataggtatgg cattagcagc agtatttgtt tttatatata caaaattagg tggagataat
     9661 acaacaacat tctatatgat atcagtatta ctaggtgttg ctgttggata ttctggagca
     9721 tggggagcat actacacaga gttgttccca agtaaatatc gttcgttgtc atctggtatg
     9781 tcatttaatg gaggaaggat tatatctacg tttgcaatac ctgctatagc tggtacagct
     9841 tctggtactt taggtatgat gactatcttt tacatatcaa tcgcagtctt tgtagcaggt
     9901 gctattgtat ggttattctt accggagacg ttaaataata aaaaataaaa tactaggaat
     9961 ttattttgtt acttagaaag gggtggctta tgatttcatc aattgatgta tgtattataa
    10021 taggatattt gctattaatg ttagttattg gttattattc aggaaaagat aataaaaatc
    10081 aagaagatta tttcttggca ggtaggtcaa tgccatggat tccaattgct ttatcagttg
    10141 cagctactat gattagtgca aatggcttta taggtggtcc tggatgggca tatgtagatg
    10201 gaatgtatcc agtaatggtt aatattacag tacctttagc aatatttttt gcactgagca
    10261 ttaccacccc agttatctat aaattaaaaa taacctctat atatgaatat atgggacttc
    10321 gtttaggaaa ttattcaaga ggcttaacta ttattcaatt ttttattaat tcattgattc
    10381 aagctagttc tatggtatat attccagtac ttattattca aatgattact ggctggtcac
    10441 tttatgcttt agtcccaata gttgtacttg tatcaattat atacactcta ttaggtggga
    10501 ttaaggcagt tatatggact gatagtattc aaatgatagt agtaataagt gctgtattta
    10561 tagtaattat tgtagcctta aaaggaatga atctaagttt ctttgataca ttacaaattg
    10621 cacaacagag tggaaaatta aatacatttg atttcagtag ggatatttca gtgacaaata
    10681 ctttttgggc tactttaatt ggtggaactg taatgtggat aagatacttc tgttttgacc
    10741 aatctcaagt acaaagagtt ttaacatcta aatctttaaa atgtgcaaaa aattcttttg
    10801 tagttagtgc atttgttatg aatttagttt actactttat gctattggta ggagtaattt
    10861 tatttgtttt ttatggggga aggacatttg aaacttcaaa tgaaataatg attactttta
    10921 ttttaaatga acttccagta ggagccattg gaattattat tgcaggtgtg tttgcagcag
    10981 caatgtctag tatcgactct atattaaaca gtatgacaac tgtttttacg aaggatattt
    11041 atgagtttta tttcaaaaaa gataacaaag aatcatcatt aaaagttaca atgattataa
    11101 ctgtagttat aggagttgtt atgacaggtt ttattattat gggatttgga ggaagcatca
    11161 aatcaattct tgaccttgtt ggtaactata tctcatactt tgctggacca gctacaggtg
    11221 catttgtact agcaatgttt acatataaag ctaatgataa aggagtatct attggtttta
    11281 ttgtagggtt agttttagga ttttttattt ctaataaata taatgtgagt tggttgtgga
    11341 atccagcaat aggtgctaca ataacattga tatttggata tatttttagt gtcattttaa
    11401 agaaaaatca taatgcagat gatattaaaa aatacactgc atttggtatg agaaatcacc
    11461 ttatttctca aggaatggat aaagtagatg gagtatctat agtgccattt tctttaggta
    11521 aacaagaact aattgtatta gcttttttta ttatccaata tattatattg tttttgatac
    11581 aattttaaga agaaatacta gatatttaag gagaaatact aaatgaatca aaagaaagtt
    11641 cattataata aatcggctac ctcaaaagat gttgcaagat tggcaggagt atctcaatca
    11701 tctgtttcaa gagcatttgg tagtgcaaat ggaaagggcg taaaacctga agtaagagaa
    11761 agaatttttc gtgtagcaaa tgaaatagga tatgttccta atttggtagc acggggaatg
    11821 attagtggaa aaactaatgt tataggattg atagttggtg atagtctagg tccattttac
    11881 aatagaatta tcaatttatt tgtagaaaaa attcaagaga taggtaaaca gtgtctcgtt
    11941 tttaaagttc ctagacaaca aagtatagat agtataattt caaaagtaat tcagtttcaa
    12001 gtagaagctg tgattattac agcttcggcc atgaataagg tgatggctga gacttgtgaa
    12061 gaaaacaata ttcctgtgat tctttttaat cgttttatac ctggtataaa aataagtaca
    12121 gtctatgtag acccaattga aggtggggga atggctgctg aatatctgct taagaaaggt
    12181 cataagaata taggatatat tcaatttacg agagaaacaa gtgaagaaat ggaaaagaaa
    12241 attggatttt attctaagtt aagacaaagt gggattcata atcttaaaga agaatctgca
    12301 aactatgatt atgattctgg atatgaagca ggtaagagaa tgttagcatt atcaaatcct
    12361 ccaacagcaa ttttttgcac aagtgacttg atagctattg gtgtaatgga tgctgcaagg
    12421 tttgagtaca agttgagggt gccagaggat ttatcagtga taggatatga tgatattcaa
    12481 atggcttcat ggaagagtta taatttaacg acgattagac agccactaga tttgttgatt
    12541 gaaaaaacaa ttaacatact taagtcctta ttaaatgaag aaaatccaga gtcagtcgtt
    12601 gaaatgttaa aacctgaatt gattgaaaga ggttctacac tttaagtggt agatatttaa
    12661 ttaagtgata gatacctaat taagttgtag atatctgata agaaattttt aagttttcaa
    12721 tcgttctaaa ttgtgagtat aaaaatctac taaatttagt tatgtaaaat ataaattata
    12781 agtgtagaaa ctaggttact agcttttata ccacttcaaa cattactgga agtagttaag
    12841 tttacagcag tttagtttta tgtagatata atattttgta aatagacaaa attaaaatat
    12901 gtaattaaaa tatgtaagtg tctcaaaatg aaatttttaa tttatgaggc acttttttgt
    12961 ataaaatcaa atatattttt ataactttaa caataaaaag aggcttatct ctattttgag
    13021 acagcctcaa atttttaaaa ctatattagt ttacagcttc ttttcctatc aaatctttta
    13081 actcttcatg agtcatagtt tctttttcaa ataagaattt agaaacagaa tgtaaatctt
    13141 caagattatc ctttaacatc tctaaagtct ctttataaca aatttcaact atacgatttg
    13201 cttccttttg aaccttatca cataagaaag tcttatcatt tccatcaata gtcataaatc
    13261 ctaagttact cataccatat tcacaaacca tttggttagc tatttcagtg actttcttta
    13321 agtcgtcctt tgcaccagta gatttatgat taaatattaa ttcttctgaa gcctttccag
    13381 caagtaatat ttttattttt ccaatcaact catccttagt ataaatatat ctatcttcat
    13441 caggtaattg aagaacataa cctaatgctt gtcctctagg aactatagat attttttgta
    13501 taggacaaat tccaactata tcacttacaa gagcatgtcc agcttcatga tatgctacta
    13561 tttttttctc tttttcaacc aatgcagagt ttttagattc tagccctgca ataactcttt
    13621 caagtgcctt gtcaaaatgt tctgatgtaa tacactcact gtcatctcta actgcaaata
    13681 tagctgcttc atttgctata tttgaaagat gagccccatt gaaaccatga gtttttttag
    13741 ctaaaagttc tagatttaca gatttgtcta taggtttgtc atctgtatgt acctttagaa
    13801 tttcaaatct agtgtgatag tttggtgcac ctatatgaat gtgtctgtca aatcttcctg
    13861 gtctaagtaa agcttcatct aataagtcaa gtctattggt agcacctatt attaatacat
    13921 tggaatcttt attaaatcca tccatttcaa ctaaaagttg gtttagtgtt tggtcttttt
    13981 cgttgttact ttcaagatgt ctctttgctc ctacagcatc tatttcgtct ataaatatta
    14041 tacttggagc ttcttttcta gctttttcaa atagagttct aactcttttt gctcccacac
    14101 ctacatattt ttcaacgaac tctgaaccgg taacattgaa aaatgatgag tttgtttcac
    14161 cagctacagc agatgcaagt agggttttac ctgttcctgg aggaccgtaa aataatactc
    14221 ctttaggtat ttttgcaccc attttttgat atttttgtgg tgacttcata aaatcgacta
    14281 tttcaaatag ttcttctttt acttcgtcta atccagcaac gtctctaaat gtagtctttg
    14341 gttttgtaga aagtgaatca tctgtttgat tatctctttc catttttgtc tgtgcaaaga
    14401 caggagctgg attgttgatt ttcttaaaaa agttgtttag cattttcata ttcacacctc
    14461 aggtaattaa ttattgttaa tcaattttat attttccata tttactattt tttattattt
    14521 atttttcatg gaaaaaatat acatgttatc taaataaaaa taaatttgta agatgtatga
    14581 aaaaatgaat ttatgtatat agagatttct acttatgtat tgaataaagt attacaaatt
    14641 ataaattatg tattgattat atattgagta aagtattata aagcatgtat tgattaagta
    14701 tttattaagt attgaataaa atattacaaa tttagttgaa atgaaaatga taaaaaatgt
    14761 tgtactatat tttacaaatc atataaatag agaaattgtt gtagcacaaa gtagtaggta
    14821 gtatattaga atataatata ggatttgttg tgtagtatag tagcatatta gaatataata
    14881 taggatttgt tatgtagtat agtagcatat tagaatataa tgtaggattt gttatgtagt
    14941 atagtagcat attagaatat aatgtaggat tgttatgtag tatagtagta tattagaata
    15001 caatatagaa tttgttgtgt agtatagtgt tatattagaa tataatatag gatttgttat
    15061 gtagaatata tagagtcatg tagaatataa atatataaaa ggattttgag tataaattta
    15121 aaaattaata gcaaaatgag tagtatagac atataattag tagtaggaag taattaaatt
    15181 tttcctaaac aaaaaaaata gttgcaaata atttgactaa gtgatatagt aaataaggta
    15241 agaataaaac aaagaagaag tccgcttctc accttacgcc ggaggttagt aaggtaaata
    15301 taagttaaag cttaatttta atttaagttt gtttaaattt ggtaacttat attgcggatg
    15361 attacgtcat ccgcttttta ttttataaaa attttggagg tgtcctacaa ttagcaaaga
    15421 attagcaatc aatgaacaaa taaaagataa ggaaataaga gtcctttcac caacaggtga
    15481 acaacttgga gtaatgccta ctaaagaagc tcaagcaatg gctaatagca aaaacttaga
    15541 tttggttcaa atctcgccga atgcaaatcc accagtatgt aagataatgg attatggaaa
    15601 gtttagatat gagcaagcga gaaaagagaa agaagctaag aaaaaacaaa aaactatagt
    15661 tgtaaaagaa gtaagactta gaccaggtat tgaacaaaat gatttaaata cgaaagctaa
    15721 taatgctata aagttcctta aaaaagggga taaagtcaaa gttgaactta gatttagagg
    15781 aagagaatta ggacataaag acataggtaa agaagttatg cttaagtttt tagatataat
    15841 aaaagagttt ggagaaccaa caaaagcccc tgcatttgag ggtaataata tggttgtaat
    15901 tatagatcca aaaaaataga tgattaactg agaggaggaa tttgtcatgc ctaaaatgaa
    15961 aactcataga ggtgcagcaa agagattaaa gaaaacagga actggaaagt taaagagagc
    16021 taaagctttt aaaaaacata tattaactaa aaaatctgca aaaactaaaa tgaacttaag
    16081 aaaatcaact ttagtaagtg atggagatgc taagagaata gcacaattat taccatacta
    16141 agatacagat tgtaaataat aactatagaa gagggatata aaaggaggtc ataacgatgg
    16201 caagagttaa aaaagctatg aacgctcgta aaaagcataa gaaaatatta aaacttgcaa
    16261 aaggattcag aggatctaga agcaaattat atagaccagc aaatacattc gtaatgaaag
    16321 cattaaaaaa tgcttatata ggaagaaagt taaagaagag agacttcaga aaactttgga
    16381 tacaaagaat aaatgcagct gctagaatga atggaatatc ttattcaaga ttaatgaatg
    16441 gattaaaatt atctggtatt gaagttaaca gaaaaatgtt atctgaaatg gctatacaag
    16501 acccagaagg atttgcaaaa ttagcagaag ttgctaaagc aaaattagct tagtattgaa
    16561 tcatgagatg taaagtcttt gagttatata aataattcaa ggactttttt attttttgaa
    16621 aaatacttat tagtgtcatg tacaaccaat tttataatga taaataaaat aagcaataca
    16681 atagaatttt atgagattta ttataagaat tgttacaatt atttatgata gctataaaaa
    16741 gtcatagtaa aaatgatatt tattcatgtt gatatatgta taaagctttc aatcaatctt
    16801 gaattaatat tatcaacatg ataatattat cttattaata atataaataa ggggaagata
    16861 atatgaatga gaaactaatg gattgttttg taaacccaat taaatgcaag ttattgcttg
    16921 aagttttttc aaataatcga actacagcta aacaattagg agaaaaattt caagatatat
    16981 caaaggcaac actttatcgt taccttaata aaatgttgaa agatgatatt ataaaagtgg
    17041 ttgaagaaaa taaaataagg ggaactgttg aaaaagtata tgctatgaag ttagatatag
    17101 ctgatgatgt gaacaaaatt atagatgaga actctggaga agaatatgct caactgttta
    17161 ctcaatatat gatgggattt ttaagagaat tttatgaata cgctgaaaga aaggaaaagg
    17221 atatcctaaa agatggttca ggattttctg tctgtccagt atatgctagt attgatgaga
    17281 tagttgaagt tagtaaaaaa attgctagta tactagaacc tctaagaaat aactcacatg
    17341 aagaaggcag aagaatgcat tctataggag tgataattac tccacctaaa gaggatgaag
    17401 ggaaataaat ctgatttaca tggggtagag ccaatttata cagggaatcg ttttatgatt
    17461 tacatatgta tccagagcaa agtatctctg cttggattgt acttcattgt atcatttcat
    17521 ttatttaatg acttggagtg gtacaatgaa gttttttaat ttttcatatt aatgcctaaa
    17581 gaaatgaact ttagaccaca tatgcaatta ggttgcatta tacaattaga ccagatatac
    17641 agaataaaaa tcagtatttt tatagcagat aaattgactg tcattcttct taaaaatcat
    17701 ctattagtta ttgttagcat attgaaagaa attatagtaa tctattgaat aaatgaatat
    17761 tgcccataat catataaact gctatagttt aaaataaagc aggacgttaa attttatagt
    17821 aatctaaaaa tttaagaggg ggattttatg aaaataaaat ttgttattat gccattggtg
    17881 atatttttaa tggtattatt tgtggggtgt caaagtacaa aagatacaga agttaaagca
    17941 aaagatacag aaattaaaat attaggtaca ggtgatttgc attcaatttt gacagactct
    18001 atggtttcat atgtaaatga ggaaagggaa aagaataaaa atctgcttat ggtagatgcg
    18061 ggagatttct atggtacaca aagtagagaa atgtgggaat ggtcttctgg aaaaaagtta
    18121 attaatatta aaagaaatgg tagagcagag tatgatgaca taattaagag tagtaaagat
    18181 gaagtaccta tagttaaaga tatggcaaag ttgaaatatg atgctgtagt tttgggagat
    18241 aatgaatttg tttcaaatga taagcaaagt cttgataaac tggtttctga ttttaaaaat
    18301 aataatatgc cattggtatc agcaaatata tatgaacaat ctggagaaaa ttatgtacaa
    18361 ccatatgtaa tgaaaaatat taagacagat gagggcaatg taaaagttgg aatactaggt
    18421 cttactataa aagaagtagg ggaaaccctt ggtcttgagg attttgaaaa ggataaaaaa
    18481 gctagagagc ttggagaaca agctgattac aaaggaaaat tatatgcaaa tgatttagta
    18541 gaagatgcaa agaaatggat aaaagttatg gaaaaagaaa gtccagacat aatagttgca
    18601 gttgtacact caggggaaga acctaaaaca gatagaaatc caggaaatag aataaaagag
    18661 ttagcaacta cagtggatgg aatagatgca attgtagctg gtcatactca tgaaaaaata
    18721 gatgaacaca aatatgaaaa taaatctgga gatgaagtaa ttgttacaca accaggttgg
    18781 catggagata gagtatcaga gattaatttc aaattaaata aagagaatgg aaagtgggac
    18841 ataaaggaaa agtctagtaa attaaaaata attgataaag aagtaagtat agttgctact
    18901 gcagatttac attcacattt ctctgataaa ttaacagttg accttgttaa tgaacgtagt
    18961 aacccaattg aacctgttgt agtagatgca ggcgacttct tagaccctca aacagatgaa
    19021 atgactcaat ggtataaaga gtggaaaagt ataagagata ataatagtga taaaacgatt
    19081 agtagatgcc caatggtcat ggatatgaat cagggaatgt atgatgcagt agtacttgga
    19141 aatcatgaat ttgtatccga aaaagatgaa ttttggtcag atgaacgcct tttagatgct
    19201 gttatagagg attttgaaca ggtggcaatt tctgtgttat cggcaaatat atataggcaa
    19261 tctggtaaaa attatgttaa accatatatt ataaaagatg tggagacgag tgaaggtaat
    19321 gtaaaagtag gaatattggg acttactata aaagaagtag gtaaaggtct taaaaatgta
    19381 aacttacaag agcaatttca atataaggat aaattgtatg caaatgattt agtggaagat
    19441 gcaaagaaat gggtaaaagt tatgaaaaag aaaaaaccag atataatagt tgcagttgta
    19501 cattcaggag aagaaccaaa acatccaaaa catccaggaa atagaataaa agaactagca
    19561 actacagtag atggtattga tgcaattgtt gctagtcata ctcatgaaaa aatagatgag
    19621 catgaatata aaaataagtc tggagaaaaa gttatagtga cacaaccagg tgagcatggt
    19681 aaatattatt ctaaaattac ctttaaagta aataaagaaa agggttcgtg gactattaat
    19741 gataaattca gtaaaacaat tgaggttgaa taactttata aaatttatag ataaagtaaa
    19801 ttatctgata ttggcatgat atataagata aagtttctaa tattagtata atgcataatg
    19861 tgaaatattt taataataag agaataaaca agacaaataa aaatatttta acatgtaaga
    19921 tatagtatga actattatac taatgcttac tttataattt gaacatgtta gaataagtct
    19981 tatttgaaaa ttttagtgta ctagagtaag tattatttta ccagtaaaaa atattgagaa
    20041 ctatatgtag atttgcttaa aaaggaattt acatatagtt cttttcgtat aataaatagt
    20101 acaatcttat atggtaaaga taaagtgtga tattaaattt tattatcatc caaaatctaa
    20161 ggaggagtct cttatgaaaa taaaatttat tatagtagca tcaataatat ttttaatagt
    20221 attacttgtg gggtgtcaaa gcactaaaga tacagaaatc aatgtactcg ccacaagtga
    20281 tttacattca attattccag ataatttaat ttcctatgta gaagaggaga gaaaatatga
    20341 tgagaatcta cttatggtag atgcaggaga tttttttgac atgcaaagtg gtgagatgaa
    20401 taagtggttt actggtcaaa aattagtaag atttaaagat gggataccag agtacaaaaa
    20461 aatagctgaa ccacgtgaag gagaagttcc attggctaaa aaaatggcaa agctgaagta
    20521 tgatgcagtt acatttggga atcatgaatt tgtatctaat gacaagcaga gccttgataa
    20581 attggtttct gattttaaaa ataacaatat accattagta tcagcaaacg tatatgaaca
    20641 atctggagaa aactacgtaa agccatatgt aatgaaaaat ataaatactg acaagggaac
    20701 tgtaaaggtt ggtatacttg gtctgactat aaaagaagta ggggaacgtt caaggtttaa
    20761 aagttttgaa caagataaaa aggctagaga acttggggaa caacctcaat acaaagggaa
    20821 attatatgca aatgatttag tagaagatgc aaataagtgg gtaaaggtta tggaaaaaaa
    20881 agaaaagcca gatataatag ttgccattgt acattcaggt gaagagccaa aaaatcctaa
    20941 aaatccagga aatagaataa aagaactagc aacaactgta gagggaatag atgctattgt
    21001 agcaggtcat acacatgaaa aaatagaaca gcatacatat aaaaataatt ctggtgaaga
    21061 agtaatagta acacagcctg gagctcatgg taatagtata tcaaagatta attttaagtt
    21121 ggataagaag aatgataagt ggtttataaa agacaaatat agtgaattaa aggtttttgg
    21181 aaaggaagta aatataatta caacttctgg tctgaatcca aaattttcag atgaaatggc
    21241 agttaatttg tttaatgaaa gagatagaga tgttcaacct atctttatag atactggaga
    21301 ttttttaaat actaatacaa aagaaatgac taattgggct aaagagtggc aatacaatga
    21361 aaataaaggc atctataaaa aaataaatga attgccaatt gtatatcttg gttatgatgc
    21421 tgtagtactt ggtagccatg aatttaaaga ggataaagag acttttgagg aaaaaaaatc
    21481 tacattggat tatattatag aaaactttga agaaatgaag ataccagtat tatcagctaa
    21541 tatatatgat gaatctggag aaaattatgt aaaaccttat ataattcata atgtagaaac
    21601 tagggaagga aatataaagg ttggagtatt aggtcttact actactgata aggatgaaga
    21661 agacttaagt agctcaagct taagcaaaga ctcaaagact tcgaaaattc ctgaagaaac
    21721 aggaaagtta tatactaata atctagtaaa agatgcaagc gaatgggtaa aagttatgca
    21781 aaaggaaagt cctgatgtga ttgttgcagt tgtacattca gataataata gtactctaaa
    21841 aaatccaagt agtgaagtca aaaaacttgc aatgtcagta gatggaatag atgctattgt
    21901 tgtaggtcat acgaaaaata aggtagaaga acatatttac aaaaataagt ctggggatga
    21961 ggttatagta acacaatctg gagaagattg ttattcaaaa ataagtcttg aactaagaaa
    22021 agaaaatggc aagtggaata tcataaacaa atatagtaaa gcaataaaaa tgaagtgaat
    22081 ttattgatat ataaaccatt attaacactg atttttataa tataataaat actgattcta
    22141 taatataatt aacactgatt tttataatat aataaatact gattctataa tataattaac
    22201 actacttttt ataatgtcat caacactgat tctataatat aattaatact acttttttaa
    22261 atataataaa tactgattcc ataatataat taacactact tttttaaata taatcaatac
    22321 tgattctaca ata
//
LOCUS       DAEORM030000059        21036 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.059, whole genome shotgun sequence.
ACCESSION   DAEORM030000059 DAEORM030000000
VERSION     DAEORM030000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 21036)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21036)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 21036)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21036
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.059"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            complement(68..757)
                     /locus_tag="KRH23_003013"
     CDS             complement(68..757)
                     /locus_tag="KRH23_003013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HHS5226290.1"
                     /translation="MSKLKDYNIDKVIIFNNLSTKTKNQLKEKVKLKRLQKKEILFYE
                     KDSLDSVYILLEGKVSIFKISENGERKVIFILNSGEVINDITLDASKNSTVGCEAFEN
                     SIVAYYSIEEFLEIMQNDFQLTKDIISYMERRIRRLYRQLKNSISIKVDKKLAAKLYR
                     LSREFGVCCGEWTLLNVNITVTYLADMLGCKRETVSRMIKVLQKEELIKIDNKGFYVK
                     ETELSRYFKSN"
     gene            complement(820..1668)
                     /locus_tag="KRH23_003014"
     CDS             complement(820..1668)
                     /locus_tag="KRH23_003014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HHS5226291.1"
                     /translation="MSILEQLESPTFKVTKSDKLLIAYIKENIDDVFYKPISQIAKES
                     NIGEATITRFVKKMNFNGLQDFKVTLAQEISTINKKNIINKNIQNDEPALDTAKKLLS
                     SNVTTLENTVEIINSKDVHDCARLIINAKKVYFIGIGYSGIIAQDSNYKFMRIGLNCV
                     SFDSSHTMIMMSSIMEEGDLIIAISHSGETEEIIKTVKLARANNAKIISITENKNSEL
                     KDISDVHLSYVSGETVLETGSISSKLAQFFIIDLVYTQVVKELSNEAIERKIKTTNAI
                     KLFKNE"
     gene            complement(1687..2574)
                     /locus_tag="KRH23_003015"
     CDS             complement(1687..2574)
                     /locus_tag="KRH23_003015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HHS5226292.1"
                     /translation="MKNYVCIDVGGTSIKYGFIREDGFIIDKSSLDTEAKEKGGEGIL
                     AKIKDIVKKYIEENEISGICISTAGMVDPVEGKILFALEELIPNYKDMQLKKEVEKEF
                     NIKCEVENDVNCAGLGEMWLGAGRGATSSICLTIGTGIGGCIIINNKLINGFSNSAGE
                     VGYMNVNGSSFQELASTSSLIKKVAKIKNLNENDLNGKIIFDLAKNNDEDCLKELDNM
                     IKSLAVGIANICYVINPEVVILGGGIMAQEKFLKPKIDKVLKEVLIERVYKNTNIEFA
                     KRQNDAGMLGALYNFLNKI"
     gene            complement(2632..3435)
                     /locus_tag="KRH23_003016"
     CDS             complement(2632..3435)
                     /locus_tag="KRH23_003016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sialate O-acetylesterase"
                     /protein_id="HHS5226293.1"
                     /translation="MENIDVFLLIGQSNARGLGNPKESIIPNENCFEYLSTDEIINMR
                     CELETSEGDGTIAPAFSNEWNKLTGNKVCFIHNAKDGSRIKNWNHDNNWFLNDTIEKF
                     NTGCTTLSKHYNIENKYVIWIQGESDAKYGSDVLYYKESLKKIAYRLKEECMIDKMFV
                     SLTGYWLGEDEYFIRTRRIAAAQESACSECDILCVGSKIAMQFHDRGLTIDDVHYTQE
                     GLNMLGEDLCKNIYKYHITKEKSVLSDTIDLSEARKYICELEKISKRFV"
     gene            complement(3595..4047)
                     /locus_tag="KRH23_003017"
     CDS             complement(3595..4047)
                     /locus_tag="KRH23_003017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HHS5226294.1"
                     /translation="MIFGNINHSKTYSTLHEDLLRCFEYAKDNSLIDYEKGTYTIDGD
                     DIFVNIVEYKTCEKEDRFWEAHKKYIDVHLMLDGCERIDINFIENLEQKIYEEKGDFL
                     PLDGKNNGYMELRKGDFLVCYPEDAHMTGIKVLEKENIKKAIFKVLVR"
     gene            complement(4177..5679)
                     /locus_tag="KRH23_003018"
     CDS             complement(4177..5679)
                     /locus_tag="KRH23_003018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter"
                     /protein_id="HHS5226295.1"
                     /translation="MVGFTWIDFAILVVYLLAVLFAGLLFSKKEMKGKEFFKGDGTIP
                     WWVTSVSIFATLLSPISFLSLAGNSYGGTWILWFAQLGMFIAIPLTIKFFLPLYSRLE
                     IDTAYEYLEMRYESKGLRVLGALMFIIYQIGRMSIIMYLPSIVLAGLTGIPVNVLIIV
                     MGVIAIIYSYTGGLKAVLWTDFIQGMVLIVGVTGTLFYLIASINGGFGTVMDTLTTGH
                     KFLASNEVMFDKNILSTSAFIIFVGAGLNTFSSYVSSQDIVQRFTTTTDIKQLNKMTY
                     GNGVLSMGLATVFYLIGTCLFIYYTQNPDLAQTVQQDQVFASYIAYELPVGITGILLA
                     AIYAASQSTLSTGLNSVATSWTLDIQTIITKDISMEKQTKIAQYISLGVGILSIAVAI
                     VLANGEIKSAYEWFNSFMGLVLGVLAGIFVLGAFCKKATKMGAYVGFIVSAILVVYLK
                     YRMPEVTSWAYSLITITTSVVVGTIVSAIEAKVKAKVSLPKAETTVYYEK"
     gene            complement(5712..6593)
                     /locus_tag="KRH23_003019"
     CDS             complement(5712..6593)
                     /locus_tag="KRH23_003019"
                     /EC_number="4.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008747 - N-acetylneuraminate lyase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate lyase"
                     /protein_id="HHS5226296.1"
                     /translation="MRTTDMKGIYSALLVSFDKEGNINEKGLRQIIRHNIDICKVDGL
                     YVGGSTGENFMLSTDEKKRIFEIAKDEVKEEIKLIAQVGSVNLKEAVELAKFTTDLGY
                     DAISAVTPFYYKFDFEEIKHYYNTIINSVDNRLIIYSIPFLTGVDMSLDQFGELFENE
                     KIIGVKFTAADFYLLERMRKTFPNKLIFAGFDEMMLPATVLGVDGAIGSTFNVNGVRA
                     RQIFELTKNEKISEALEVQHVTNDLITDILGNGLYQTIKLLLEEQGVEAGYCRQPMKE
                     ATDEMKSRAKEIYRKYF"
     gene            complement(6663..7334)
                     /locus_tag="KRH23_003020"
     CDS             complement(6663..7334)
                     /locus_tag="KRH23_003020"
                     /EC_number="5.1.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047465 - N-acylglucosamine-6-phosphate
                     2-epimerase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006051 - N-acetylmannosamine metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019262 - N-acetylneuraminate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HHS5226297.1"
                     /translation="MLDKVKGRLIVSCQALEDEPLHSPFIMGRMAKAAMEGGAVGIRA
                     QGVEDIIEIKKVTGLPVIGIIKRNYEDSDIYITPTKKEVDELLTTGCEMIALDATNRV
                     RPNNEDLKELIKYIKENGVLVMADISNYDEAIKAQEYGVDCVSTTLSGYTPYTKTLEG
                     PDFVLMERLVKDLEIPVIAEGKVNTPQDLKKVFELGVHSSVVGSAITRPQLITEKFVK
                     AIEIN"
     gene            complement(7605..8096)
                     /locus_tag="KRH23_003021"
     CDS             complement(7605..8096)
                     /locus_tag="KRH23_003021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HHS5226298.1"
                     /translation="MEGNTNNKVDDKFSKVKKKFGSGKFKVELYKEKSKLNREIDDIQ
                     EEKAKIFLEMGILTYQKIREDSINDNSFDKFCDELLELDKLIYEKNMEINEMEMAESN
                     VTCECGYVGNVNDKYCAECGKKFELENECDDFIICGYCESEIDTEAEFCPCCGRKIIM
                     DLE"
     gene            complement(8118..9482)
                     /locus_tag="KRH23_003022"
     CDS             complement(8118..9482)
                     /locus_tag="KRH23_003022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HHS5226299.1"
                     /translation="MGEKKINNMNYSHNNYSKKTGEPTRKIKNSHITLKSKEEKICSS
                     CNKENNTKDNYCKFCGNELYEIASLRPLETKLDLKSKIKELSYHANKRGVFLTTFTTI
                     FILFIIALIFKAIITIQFNDISYLVNPAHIILALNLGQISVSMSTMMGSGFINANIGL
                     LILLIIPILVLLISNLIFMRKRCRDSKTVLANSLGVGIFYGLVLAILSIFTNVKTSSH
                     SMLEYGYALEYSYEFFSVLLNGFVLGFICTYITTYKKSYEKENMYLSLFSNSIRTFIL
                     GYVLVLVILLVLTISDSSYLNELDMSSYSNGLNLFTILPQIASYMWAFANGISVTIIN
                     STVSMFTLSSSSLFGDTKLMFYAMGALSMLILLLNGYKLRFKYNTDSIRPIIVFSIYY
                     AFLMGILALFSTFILDSNINFFNTTNYGTTLIMQFKVLQAIVISFVYSFVISLIGYKL
                     NSAD"
     gene            9901..11076
                     /locus_tag="KRH23_003023"
     CDS             9901..11076
                     /locus_tag="KRH23_003023"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0052621 - diguanylate cyclase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HHS5226300.1"
                     /translation="MNLEKIKKFFGFPLDKKHKDNVEKELCNYLYHTGKIICIIIVIS
                     QIIMMISISAREGGPFVTPRRQWYFYMYVTLFCVSSVFMFVFSYLWNKKKDCCTFYIN
                     LWIIYVTFFCLWGCVITLLDQLGGNDLSVFSYIMLAAAAFSVLKFGESVIVFGGCFLF
                     LNLFLPGIQTIPGNEFSNIVNTFFITSLAIFVSTMLYRNRVFTYYDKLLISQQYEEIS
                     HINNLLNDKVMTDDLTKMNNRRYLEDILQKKLISHANQEPITGMMIDIDYFKQFNDNY
                     GHQKGDYCLQNIAKVILDFTSSENEHAIRYGGEEFFICIFNCNEAEAKLKSECLRKII
                     ECCNFERDDVPLKCVTVSIGVYTKKIEKTITLNEFISNCDKALYTAKEQGRNCVAFY"
     gene            complement(11249..12646)
                     /gene="asnS"
                     /locus_tag="KRH23_003024"
     CDS             complement(11249..12646)
                     /gene="asnS"
                     /locus_tag="KRH23_003024"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004816 - asparagine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006421 - asparaginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HHS5226301.1"
                     /translation="MQKEFITVKELYREKEQYIGKTVKVAGWIRTSRVSKNFGFIELN
                     DGSFFKNMQIVFDEKVENFKEVGKLAISSSILVEGELVSTEGAKQPVEIHAKSIVVEG
                     ESDSSYPLQKKRHTLEYLRTIAHLRPRSNTFSAVFRVRSIAAYAIHKFFQERNFVYAH
                     SPIITGSDCEGAGEMFRITTMDLNDIPKTEDGKIDYTQDFFGKEANLTVSGQLNAEIM
                     ALSFRNVYTFGPTFRAENSYTGRHASEFWMIEPEIVFADLEDNMELAEDMIKYVISYV
                     LENAPEEMEFFNSFIDKGLLERLNKIVNSEFIRITYTKAVELLIESGHEFEYPVEWGC
                     DLQTEHERYITEQIYNCPVFVTDYPKDIKAFYMRMNEDGKTVRAMDLLVPGVGEIVGG
                     SQREEREDVLLDRINEMGLREEDYWWYLELRKFGTATHSGFGLGFERIIMYMTGMSNI
                     RDVIPFPRTPKNAEF"
     misc_binding    complement(12723..12956)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(13125..13319)
                     /locus_tag="KRH23_003025"
     CDS             complement(13125..13319)
                     /locus_tag="KRH23_003025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDIF630_02480 family spore surface protein"
                     /protein_id="HHS5226302.1"
                     /translation="MESKKARALKGKDNKRLKSSLLVGNESTAAWADVEKLKPHSKVS
                     IPSIKGVEEAKDWVDNGSKL"
     gene            complement(13592..15265)
                     /gene="cspC"
                     /locus_tag="KRH23_003026"
     CDS             complement(13592..15265)
                     /gene="cspC"
                     /locus_tag="KRH23_003026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bile acid germinant receptor pseudoprotease
                     CspC"
                     /protein_id="HHS5226303.1"
                     /translation="MEKSYCIIYQGDIESALQENGINRYMVLNSQLAVIYVPLDFDET
                     ILNNIIQVAWWEESEPMSSLIEITNNVNNGETITTAAETDYIYENPYNDITGRGILLA
                     VIDSGIDYLHPDFINDDGTSKVLYLWDQEANTNPPPEGFIFGSEFTRSELNIAINRND
                     GSLSQDNIGTGTLVSGILVGNGRINSQYRGITTESDLIVVKLKSYTDTYYAGRINYSV
                     SDFLAAITYVTNIARTENKPLIINLTIGVKSSAVATTSILDTFNILSSAGVVVVSGAG
                     NQGNTDIHYSGRFSSVGEVQDVIIQDGDDYALDITLNTNGPDKVGAQIISPSGEVSHD
                     IRYSPDFYIYRGKFNLENTTYAMRFIYPYITSGKENLEIRLRDIKPGVWILRLTSELI
                     INGEYDIYLPNKNLIAPDTRFLDPDSVATITMYAASDDVITVGTFNNKTDSMWIGSSK
                     GPIRGRGIKPDIVASGVDIISTYKNGTYNTGTGTGVSSSIVTGVLALLMEYLEKQDNV
                     PRLSLFTQVLKTYLILGATKLEIYTYPNVSQGYGILNLKNTIQQIANTL"
     gene            complement(15275..18673)
                     /gene="cspBA"
                     /locus_tag="KRH23_003027"
     CDS             complement(15275..18673)
                     /gene="cspBA"
                     /locus_tag="KRH23_003027"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional germination protease/germinant
                     receptor pseudoprotease CspBA"
                     /protein_id="HHS5226304.1"
                     /translation="MIIINYELIVKYNGDILRLEEELGVSVEILNSSYAIITSSNEED
                     VNILLTYPEIEFIEKPFILQTQDVQSFSSTGITGFKNRTGLTGKGTIIGIIDSGIDYT
                     LPVFRDSDGRSKILYYWDQSIQGNPPEGFREGTLYTNEDINNAIDGSMYIPISTTSLH
                     GTHVAGICATIASDARIIVVRVGNIQTDIFSRSTEFMRAIKFILDRALELRMPVTLNI
                     SYGSNEGSHRGTSLFEQYIDDMCLFWKNNIVVAAGNNADKGGHKRIRLQNNITEEVEF
                     IVGEGERILNINIWPDFVDDFSVHLVNPSNNQTQAISLTSGEIRNTLGETRITGYFYP
                     IAPYSLTRRVTLQLSSNTQITPGLWKIVFEPIDIVTGNVNIYLPTSEGLNRNTRFLIP
                     TQELTVTVPGTASRVITVGSFNSRTDIVSIFSGEGDTQLGVFKPDLLAPGEDIVSFLP
                     GGTSGALTGTSMATPHVTGVCSLFMEWGIVNGNDLFLYSQKLRALLLKGARRLSNQSY
                     PNNSSGFGFLNLSDIDLYTLSNINQDLETEDIGYRSINKSFKDEENSYKFIDGYNMQI
                     HNDLENEIYISKNASRQSGILSGIDIVHTPEFEEELAGLGMSQRFFKISDSLGVLSIN
                     NTDYNSIQRVLQLPSIIRTVSTTKMTLLGEINRGTFGGVVATEEMGVNFFKNNPNINI
                     TGRGTLISIADTGIDYLHPDFIYPDGTSKIVYLWDQTKEGTPPDGFYIGTEYTREDIN
                     RAIAENDPSLSQDEVGQGTMLSGICAGLGNVNSEYAGIAEDSELIIIKLGKIDDFYNS
                     AMLFAASQYAYKKAFELGRPLVINMSLGTSSLAGLTNRSNSEKAFFTRGLCITAGAGN
                     EGNTQTHTSGIIPYVGGSVEVELELNEDEEELSLELWLNRPDKADVIIVSPTGEESKS
                     VGISNYNKVTGLFDLEGTEYSITYIYPTTFSGQQFTNVTLKNAKRGVWKIRLVGVYII
                     TGRYNLYLPNRELLKSGTRFREVDPFYTINYPAIQDDLITIGAYNTINGSLWQSSSRG
                     PTIEDRLKPDIVAPGVNIIAAYPGNTYATITGTAAASAHAAGAAAMYFQYTFVDGRYP
                     NQAYVQKIKTFMQAGARKDSNTVYPNTNSGYGLLDVRGMFDVLR"
     gene            complement(18841..20037)
                     /locus_tag="KRH23_003028"
     CDS             complement(18841..20037)
                     /locus_tag="KRH23_003028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009297 - pilus assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="vWA domain-containing protein"
                     /protein_id="HHS5226305.1"
                     /translation="MFIEFFYLLRSRGLNVSLNEWMTLIEALDKGLCYSNFSNFYYLC
                     RMILIKSESDFDKFDAVFLEYFKGIEHQEEIPEEIMNWLKKPDIDLEEFERLEQNPNI
                     NLDKLRAKLEERIKEQDSPHNGGNYWIGTGGTSELGHSGKGQTGIRIGGNSTYGRAVL
                     EVAGERKYRDFRDDEVLNMRQFQVALKRLRQFSTRIDAPKTELDLDKTIEETCNNAGY
                     LKLFFEKPRKNTVKLLLLMDSGGSMRGYSTLCNTLFQSVSKSNHFKDVKIYYFHNCIY
                     DRLFTTPECWLSKSINTEWILKNIDKNYKVIIVGDASMSPSELLHIGGNYRGPYNYTP
                     GIEWLKRFKRKYSKIVWMNPELRDGWDSINYWYQTQRMIKSEFNMFPLTVKGLEKALK
                     NLMVSR"
     gene            complement(20058..20879)
                     /locus_tag="KRH23_003029"
     CDS             complement(20058..20879)
                     /locus_tag="KRH23_003029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HHS5226306.1"
                     /translation="MIKKEISNFRGSSDYVVSPELMASVNVAIALEKPLLIKGEPGTG
                     KTMLAQAISNELKKDLVIWNIKSTTKAQEGLYVYDTVQRLYDSQFGGEGVDDISKYIK
                     YGKLGEAFSSNQQVILLIDEIDKADLEFPNDLLWELDKMEFYINETKETVRAKQRPIV
                     IITSNAEKELPDAFLRRCIFHYIEFPDRDMMEEIVKVHFDKVEEHLLEQVMTTFYWIR
                     SLKDIQKKPSTSELIDWIQALTLSGMPIEKIEKKVPFAGILLKNNEDIESMQRHL"
BASE COUNT         6787 a         3768 c         2222 g         8259 t
ORIGIN      
        1 taaatagatt ctcttaataa tatttttatt taattaaaat tctaataata ctcttactta
       61 atcataatta attactttta aaataccttg ataattcagt ttctttaaca taaaaacctt
      121 tattgtcaat tttaataagt tcttcttttt gcaatacctt tatcattctg gaaacagtct
      181 cccttttaca gccaagcata tcagctaaat atgtaactgt aatatttaca tttagtaaag
      241 tccattctcc acagcaaact ccaaattctc tacttaacct atataatttt gctgcaagtt
      301 ttttatctac ttttatagat atagaatttt tcaactgtct atataaacgt cttattcttc
      361 tttccatata agaaataata tcctttgtaa gttgaaaatc attttgcata atttctaaaa
      421 attcttcaat actataataa gctacaattg aattttcaaa tgcttcacag ccaacagtag
      481 agtttttaga agcgtcaagt gtaatatcat ttatgacttc cccactattt aatatgaaaa
      541 ttacttttct ctctccattt tcacttatct taaaaataga tacctttcct tctaaaagta
      601 tataaacact gtctaagcta tctttttcat aaaataaaat ttcttttttt tgtaatcttt
      661 ttagtttaac tttttcttta agttgattct tcgttttagt acttaaatta ttaaaaatta
      721 ttactttatc aatattataa tcttttaatt tagacatgta atatctctcc attcctaaat
      781 ttttaagaga gctctataaa acattacaaa tttcttattt tattcatttt taaacaattt
      841 tatagcattt gtagttttaa ttttcctttc aatagcttca ttagaaagtt cttttactac
      901 ctgtgtatat actaaatcaa taatgaaaaa ttgtgctaat ttagaagata ttgaaccggt
      961 ttccagtact gtttctcccg atacataaga taagtgtaca tctgaaatat cctttaattc
     1021 agaattttta ttttcagtaa ttgatataat tttagcatta ttggctcttg caagctttac
     1081 agtttttata atctcctctg tttcaccaga atgtgaaatt gcaattatta aatctccttc
     1141 ttccattatg gaagacatca ttatcattgt atgactactg tcaaaactca cacaattaag
     1201 acctattctc ataaatttat agtttgaatc ctgtgctatt ataccagaat atccaatacc
     1261 tatgaagtaa actttctttg catttattat aagccttgcg cagtcatgta catccttact
     1321 attgattatc tctactgtgt tctctaaagt ggttacattt gaacttaaaa gtttttttgc
     1381 tgtatccaaa gctggctcat cattttgtat atttttattt ataatatttt ttttattgat
     1441 agttgatatt tcttgtgcta aagtaacttt aaaatcctgt aatccattaa aattcatttt
     1501 ttttacaaac ctagttatag ttgcttcacc aatattgctc tctttagcta tttgtgatat
     1561 tggtttataa aatacatcat ctatattttc ttttatataa gctattaata atttatctga
     1621 ttttgtgact ttaaaagttg gtgattccaa ttgttctaaa atactcatta aaaacccttc
     1681 tattctttat attttattta aaaaattata taatgctcca agcattcctg catcattttg
     1741 tctctttgca aattctatat tagtgttttt gtaaactctc tctataagaa cctcctttaa
     1801 tactttgtct atttttggtt ttaggaactt ttcttgtgcc ataatcccac cacctaaaat
     1861 taccacttct ggatttatta cataacatat atttgcgatt ccaactgcta atgattttat
     1921 catattatcg agttctttta aacaatcttc atcattattc tttgctaaat caaaaattat
     1981 ttttccattt aagtcatttt cattcaaatt ttttattttt gctacttttt taattagact
     2041 gctagtagat gccaattctt gaaaagaact tccatttaca ttcatatatc ctacttcacc
     2101 agcactatta ctaaacccat ttatcagttt attatttatt ataatacatc caccaattcc
     2161 agtacctatt gttaaacata tagaagatgt tgcacctcta cctgctccaa gccacatttc
     2221 accaagtcca gcacaattaa catcattttc aacttcacat tttatattaa actctttttc
     2281 tacttctttt tttaattgca tgtccttata gtttggaatt aattcttcta atgcaaatag
     2341 tattttacct tcaactgggt caaccatacc tgcagttgat atacatatac cacttatttc
     2401 attttcctct atatattttt ttactatatc ttttattttg gctaatattc cttctccgcc
     2461 tttttccttt gcttcagtat caagacttga tttatcaatt ataaatccat cttctctaat
     2521 aaaaccatat tttattgaag tacctccaac atctatacaa acgtaatttt tcataacata
     2581 tctccataca aattattttt ataaattaac aactctattt aaaattttat attacacaaa
     2641 tcttttactt atcttttcca attcacagat atatttcctt gcttctgata agtctatagt
     2701 atcacttaat acactttttt ctttggttat atgatactta taaatatttt tacataagtc
     2761 ctctcctaac atattaagac cttcttgagt gtaatgaaca tcatcaatag ttaatcctct
     2821 gtcatgaaac tgcatagcaa ttttgcttcc tacacataat atatcacatt cactacaagc
     2881 cgactcctgt gctgctgcaa ttcgtcttgt tctaataaaa tattcatctt ctccaagcca
     2941 ataaccagtt aaacttacaa acattttatc aatcatacat tcttctttaa gcctatacgc
     3001 aatttttttt agactttctt tatagtacaa tacatcacta ccatattttg catcactttc
     3061 accttgaatc caaataacgt atttattttc tatattataa tgtttactta aggtagtaca
     3121 gcctgtatta aatttttcta tagtatcatt tagaaaccag ttattatcat gattccagtt
     3181 ttttattctt gaaccatctt ttgcattgtg aataaaacaa accttatttc cagtaagctt
     3241 attccattca tttgaaaatg caggtgctat agtaccatca ccttctgaag tctctagctc
     3301 acatctcata tttataattt catcagtact caaatattca aaacaatttt catttggaat
     3361 gatgctctct tttggatttc ccaatcctct agcattgctt tgtcctatta ataagaatac
     3421 atctatattt tccataagtt aactccttta caaaatttta agcttttaat tattttcaat
     3481 tttctcataa aaaactaagg ctgaaaatag taatctaact aaaatttacg aagtctcact
     3541 aatcgctgaa agttaaatca ctattttcag ccctagtggt tatataaatt atcattatct
     3601 aaccaaaacc ttaaaaatag cttttttgat attttctttt tctaaaactt ttattcctgt
     3661 catatgagca tcttccggat aacaaactaa aaaatcacct tttctaagtt ccatgtatcc
     3721 attattttta ccatcaagag gcaagaaatc gcccttttct tcatatattt tttgttctaa
     3781 attttctata aaatttatat ctattcgttc acatccatca agcatcaaat gaacatctat
     3841 atacttctta tgagcttccc agaatctatc ttctttttca caagttttat actctacaat
     3901 attcacaaaa atatcatcac catctattgt ataagtacct ttttcataat ctattaatga
     3961 attatcttta gcatattcaa aacatctaag taaatcttca tgcaatgttg aatatgtctt
     4021 actatgattt atatttccaa atatcataag cactatctcc ctatataatt ataaagtcta
     4081 tttttatact tttatataca aagtatatta tacaatctta tagagtaact aaattattta
     4141 tctaatcact ctataagaca atttatcatt taaatattat ttttcataat aaacagtagt
     4201 ctcagctttt ggtaaagata cttttgcttt aactttagct tctattgcac taactattgt
     4261 acctaccact acagaagtcg tgattgttat tagagaatat gcccaagaag ttacttctgg
     4321 catacggtat tttaaataaa caactaaaat tgctgatact atgaatccaa catatgctcc
     4381 cattttagtc gcttttttac aaaatgcacc aagtacaaat attcctgcta aaacacctag
     4441 tactagcccc ataaaactat taaaccattc atatgctgac tttatttctc catttgctaa
     4501 tactattgca acagctatag aaagtatacc tacacctaat gatatatatt gtgctatctt
     4561 agtttgcttt tccatactta tatcttttgt tatgatagtt tgtatatcta aagtccaact
     4621 tgtagcaact gaattaagcc ctgtcgataa agttgattga gaagctgcat atatcgctgc
     4681 aagtagtatt cctgttatac ccactggtaa ttcataagct atatatgatg caaatacttg
     4741 gtcttgttga actgtttgag ctaaatctgg gttttgagta tagtatataa ataaacaagt
     4801 tccaattaga taaaatactg ttgcaagtcc cattgataaa acaccatttc catatgtcat
     4861 tttattaagt tgctttatat cagttgttgt agtaaacctt tgaactatat cttgactcga
     4921 tacatatgat gaaaaagtat taagaccagc tccaacaaat attataaatg cacttgtaga
     4981 tagtatattt ttatcaaaca taacttcatt acttgctaag aacttgtgtc cagttgtaag
     5041 agtatccatt actgttccaa aaccaccatt tatacttgct attaaataga acaatgtccc
     5101 tgtaacacct actattaata ccattccttg tataaaatcg gtccacaaga cagcctttaa
     5161 tccacctgta tatgagtaaa ttattgctat tacacccata actattatca gtacatttac
     5221 aggtattcct gtaagaccag ccagaactat tgatggaaga tacattataa tagacatacg
     5281 tcctatttga tatattataa acatcaaagc gccaagtact ctaagacctt tgctttcgta
     5341 tctcatttct aagtattcat atgctgtatc tatttctaac ctactatata gaggtaagaa
     5401 aaattttatt gtcaaaggta ttgctataaa catacctaat tgtgcaaacc acaaaatcca
     5461 agtaccacca taagaatttc ctgctaatga taaaaatgat attggactta ataatgtggc
     5521 aaatattgat actgatgtaa cccaccacgg aatagttcca tcacctttga agaactcttt
     5581 tcccttcatt tccttttttg aaaataacaa tcctgcaaat aaaactgcca ataagtaaac
     5641 cactagtatt gcaaaatcta tccaagtaaa tcctaccatt tgactaatcc tcccatacta
     5701 aaagtatttt attaaaaata ctttctgtat atttcttttg ctcttgattt catttcatca
     5761 gttgcttctt tcataggttg tctacagtat ccagcctcaa caccttgttc ttcaagtagt
     5821 aatttaattg tttgatataa gccatttcct aatatatctg ttattaaatc attagtcaca
     5881 tgttgtactt caagtgcttc tgatattttt tcattcttag ttaattcgaa tatttgtcta
     5941 gctctgacac cgtttacatt gaatgtagaa ccaattgccc catctacacc taaaactgta
     6001 gctggtaaca tcatttcatc aaatcctgca aatattaatt tatttgggaa tgtttttctc
     6061 attctctcta ataagtagaa atctgctgct gtaaacttaa cacctattat tttttcattt
     6121 tcaaataatt ctccaaactg gtctaaactc atatcaacac cagttaaaaa tggtatagag
     6181 tatattatta atctattatc tacagaattt attattgtat tataatagtg ttttatttct
     6241 tcaaaatcaa atttatagta aaaaggtgta acagcactta ttgcatcata tcctaaatca
     6301 gttgtaaatt tagcaagttc tacagcttct tttaaattaa ctgaaccaac ttgagctatt
     6361 aattttattt cttctttcac ttcatcttta gctatttcaa atattctttt cttttcatca
     6421 gttgaaagca tgaagttttc ccctgtactt cctcctacat aaagaccatc tactttacaa
     6481 atatctatat tgtgtctaat tatttgtctt aacccttttt catttatatt tccttcctta
     6541 tcaaatgaaa ctaataatgc tgaataaatt cccttcatat ctgttgttct catatcttta
     6601 cctccaattt taattttcaa atatagttaa atataataat tttttaattt ataaattaat
     6661 ttttaattaa tttcaattgc tttaacaaat ttttctgtta ttaattgtgg tcttgttatt
     6721 gctgaaccta ctactgatga atgaacaccc aactcaaaga ccttttttaa atcttgagga
     6781 gtatttacct ttccttcagc tattacaggt atttctaaat ctttaactaa tctttccatt
     6841 aatacaaaat ctggaccttc taatgtttta gtatatggag tatatccaga tagtgtagtt
     6901 gaaacgcaat ctacaccgta ctcttgtgct ttgatagcct catcataatt tgaaatatct
     6961 gccattacta gaacaccgtt ttcttttata tactttataa gttcttttaa gtcttcatta
     7021 tttggtctaa ctctattggt agcatctaat gctatcattt cacaccctgt tgttaaaagt
     7081 tcatcaactt cttttttagt tggcgttata tatatatctg aatcttcata gtttctcttt
     7141 ataataccta taacaggaag tccagtaact ttttttattt caataatatc ttcaactcct
     7201 tgagctctaa ttccaacagc tccaccttcc atagcagcct tagccattct ccccattata
     7261 aaaggactat gaagaggttc atcttctaaa gcttggcatg atactattaa tcttcccttt
     7321 accttatcta gcatttttta aattacctcg tttctgaaat ttattttctt gatttatgta
     7381 ttaataataa catgaaaact ttttctttgc aatatttttt catttttttc ttgtatctat
     7441 atttttactg atttatttta tatattagct tgctttttac atttaaaaga aattttattt
     7501 catttttttg gtgtttattt tcattttata caactactgt tataagtcca tttaaataat
     7561 ttcaataaaa aaacccatgt atactataca taggtttccc aatattattc taaatccatt
     7621 ataatttttc ttccacagca tggacaaaat tcagcctctg tatctatctc actttcacaa
     7681 taaccacaaa ttataaaatc atcacattca ttttccaatt caaatttttt accacattca
     7741 gcacaatatt tatcatttac atttccaaca taaccacact cacaagttac attactttct
     7801 gccatttcca tttcattaat ttccatattt ttttcataaa ttaacttatc aagttctagt
     7861 aactcatcac agaatttatc aaaactatta tcattaatag aatcttctct aattttttga
     7921 tatgtcagta ttcccatttc caagaatatc tttgctttct cttcttgaat atcatcaatc
     7981 tctctattta attttgattt ttctttatat aattcaactt taaattttcc actaccaaac
     8041 tttttcttaa ccttagaaaa tttatcatct actttattat tagtatttcc ttccacagaa
     8101 attccctcca atcatattta atcagctgaa tttagcttat atcctattaa agatatcaca
     8161 aaactatata caaatgaaat cacaatagct tgtaagactt taaattgcat tattaaagtt
     8221 gttccataat tagttgtatt aaagaaatta atattactat ctagtataaa tgtactaaat
     8281 aaagccaata ttcccatcaa aaatgcataa tatatactaa atactattat aggtcttata
     8341 ctatctgtat tatacttaaa tcttagcttg tatccattta ataataatat taacatagac
     8401 aatgctccca ttgcataaaa cattaattta gtatctccaa ataaagatga agaacttaaa
     8461 gtaaacattg atactgttga gtttattatg gttactgaaa ttccatttgc aaaagcccac
     8521 atataactag ctatttgtgg gagtatagta aataaattta atccatttga ataactactc
     8581 atatctagtt catttaagta actactatca gatatagtta gtaccaatag tattactaat
     8641 actaaaacat aacctaatat gaatgttctt atagaatttg aaaaaagaga taaatacata
     8701 ttttcttttt cataactttt tttataagta gttatgtatg tacatataaa ccctaatacg
     8761 aatccattta aaagaacact aaaaaattca taactatatt ctaatgcata tccatattct
     8821 aacatactat gtgaactagt ttttacatta gtaaaaatag ataaaatagc taaaactaat
     8881 ccataaaaaa ttccaactcc tagagaattt gctaatacag tttttgaatc tctacatctt
     8941 tttctcataa aaattaggtt tgatattaat aataccaaaa tagggattat aagtaatatc
     9001 aacaaaccta tattggcatt tataaaccca gagcccatca tggtagacat agatacacta
     9061 atttgaccca agttgagagc taggattata tgtgctggat ttactaaata actaatatca
     9121 ttaaattgaa tagttataat agctttaaat atcaatgcaa taataaacaa tataaatatg
     9181 gttgtaaatg ttgttaaaaa tacacctctt ttatttgcat gatatgaaag ctcttttatt
     9241 ttagatttca agtctagttt tgtttcaagt ggtcttaatg atgctatttc ataaagttca
     9301 tttccacaaa atttacagta attatcctta gtattatttt ctttattgca actagaacaa
     9361 attttttctt ctttactttt aagagtgata tggctatttt ttatttttct agttggttca
     9421 cctgtctttt tggaataatt attatgtgaa taattcatat tatttatttt cttttcaccc
     9481 attttttccc tccaagtttt actattgtaa attatcaaat ataactatat catataaaac
     9541 ttaattatac cttaattgga tatatttatc tattttattt gtttattgct gttgtttttt
     9601 aacaggtctt gatatttaaa tagtttgtta atgcgaactt tattatttat attttattat
     9661 gcttaattta aatttattct attctttatt ttcagtagta aactatctgt aaatcttaat
     9721 tataataaag tattaatcaa taaagttact cgacattatc taataaattt tatctatcac
     9781 aattttagat tgttacacac aatatatttt gatataatta aatcataaac gaagtattcc
     9841 aaatatctaa tgatagaaag gaatacttat ttttatgctt tatttttaat ggaggcttat
     9901 atgaacttag aaaaaataaa aaaatttttt ggatttcctc tagacaaaaa acacaaagac
     9961 aatgttgaga aagaactctg caattatctt tatcatacgg gtaaaatcat ttgcataata
    10021 atagtaatat ctcaaataat tatgatgata tcaatctcag ctagagaagg aggccctttt
    10081 gtcacaccaa gacgccaatg gtatttttat atgtatgtaa cactattttg tgtatcttct
    10141 gtctttatgt ttgtattttc ttacctttgg aataaaaaaa aggattgctg tacgttttat
    10201 ataaatttat ggataattta tgtgactttt ttctgcctat ggggttgtgt aattactcta
    10261 cttgaccagt taggtggaaa tgacctaagt gtatttagtt atattatgtt agcagctgca
    10321 gctttctcag tattaaaatt tggagaatca gtaatagttt ttggaggatg ctttttgttt
    10381 cttaatttat tcttacctgg gattcaaact ataccaggca atgagtttag taatattgtc
    10441 aacacatttt ttataacatc ccttgccatt tttgtttcta caatgctata tagaaatcgt
    10501 gtatttactt actatgataa acttttaatt agtcaacaat atgaagaaat atctcatata
    10561 aataatttac ttaacgacaa agttatgaca gatgacctta ctaaaatgaa caaccgtagg
    10621 taccttgaag atattctaca aaaaaaatta atcagccatg caaatcaaga acctataact
    10681 ggaatgatga tagatataga ttattttaaa caatttaatg ataattatgg acatcaaaag
    10741 ggagactatt gtctacaaaa tattgccaaa gtaattttag attttacaag ttctgaaaat
    10801 gaacatgcta tacgatatgg tggtgaggaa ttttttatat gtatttttaa ctgtaatgag
    10861 gcagaggcta aacttaaatc agaatgttta cgaaaaatta tagagtgctg caattttgag
    10921 cgtgatgatg ttcctttaaa atgtgtaact gttagtattg gagtttatac aaagaaaatt
    10981 gaaaagacaa taacattaaa tgagtttata agtaattgtg ataaggctct atatactgca
    11041 aaagaacaag gacgtaattg tgttgcattt tattaaaaag ttacatacta ttacataaac
    11101 ctataagtat tatatcgcaa aataaaagta atcaaattat atatttatag tacaataaaa
    11161 ataacttgca tatctctaaa atagataaat atgcaagtca ttttagtgtt tatacttaaa
    11221 gttatatagg ttttattata tataattatt aaaattcagc atttttagga gttcttggga
    11281 aaggtataac gtctcttatg ttagacatac ctgtcatata cataattatt ctttcaaatc
    11341 caagaccaaa tccagagtga gtagcagtac caaactttct aagttctaaa taccaccaat
    11401 aatcttcttc tcttaatccc atttcattaa ttctatctaa caatacatct tctctttctt
    11461 ctctttgaga acctcctacg atttctccaa ctccaggaac tagtaaatcc attgctctaa
    11521 cagttttacc atcttcattc attctcatat agaaagcttt tatatctttt ggataatctg
    11581 taacaaacac tggacaatta tatatttgct ccgttatata tctttcatgc tctgtttgaa
    11641 ggtcacatcc ccactcaaca ggatactcaa attcatgccc agattcaatt aataattcca
    11701 ctgctttagt atacgttatt ctaataaact cagagtttac tatcttattt aatctttcta
    11761 acaatccttt atctataaaa ctattaaaaa attccatttc ttcaggagca ttttctaata
    11821 catagcttat aacatatttt atcatatctt ctgcaagttc catgttatct tcaaggtctg
    11881 caaaaactat ttctggctct atcatccaaa attctgaagc atgtcttcct gtataagagt
    11941 tttcagctct aaatgtaggt ccaaaagtat aaacgtttct aaaagaaagt gccattatct
    12001 cggcatttaa ttgaccacta actgttaaat tagcctcttt tccaaagaaa tcttgagtat
    12061 agtctatttt gccatcttca gtttttggaa tatcatttaa atccatagtt gttattctaa
    12121 acatctctcc tgcaccttca cagtcactac ctgttatgat tggagaatgt gcatatacaa
    12181 agtttctttc ttggaagaat ttgtgtattg cataggcagc tattgatctt actctaaata
    12241 cagctgaaaa agtattactt cttggtctta aatgtgctat cgttcttaaa tattcaagcg
    12301 tatgtctctt cttttgtagt ggatacgaac tatctgattc cccttctaca actatgcttt
    12361 ttgcatgtat ttcgactggt tgtttagccc cttctgtaga tactaactct ccctctacaa
    12421 gtatagatga gcttattgct aattttccta cctctttaaa attttctact ttctcatcaa
    12481 atactatctg catattttta aagaagcttc catcatttag ctctataaat ccaaaatttt
    12541 tagatactct agatgttctt atccatccag ctacttttac agtcttccct atgtactgtt
    12601 ctttttctct gtacaattct tttactgtta taaattcctt ttgcatttta aatcctccta
    12661 gtataattgt tattaatttc ttttaaatat aatttcaata aaaaaagccc ttcatcccta
    12721 tataaaggga cgaaagacta ttactctcgc ggtaccaccc tagttgtcat aatgacctct
    12781 tagttaagca atgcttaaag cctataacgg tgccttccgt ctaagtctac ttactaaata
    12841 agctttcgat tagaaactcc aagatgttct tcaatataaa cctcgtattg agctttcacc
    12901 atcctcaact cgctagaact acattttata tctactcttc tcttcacagt atttatcttt
    12961 tattatttct gctaattaac aaaattatac caatttataa atttttagtc aataaattta
    13021 tataattgat actgattgtt atttaaaata taataattct accttacata atgataataa
    13081 atacttatct tcattacttc tttattactt caatttccaa aattttataa tttacttcca
    13141 ttgtcaaccc agtcttttgc ttcttcgaca cccttaattg aaggtattga aactttacta
    13201 tgaggtttta atttttcaac atcagcccat gctgctgtcg actcatttcc aactaaaagt
    13261 gaacttttaa gtcttttatt atctttacct tttaatgctc ttgccttttt actttccaaa
    13321 actatcacct ctattattta ttttgtaata gttttagcaa ttttacaaat aaaattcata
    13381 agtctaaatt ataattattt ttaaattaac atcatatctt ttcaatactt aatttatacc
    13441 tatttatata caaaatattt actttgtgta ttcaaaatat aaaactgttt tttaattttc
    13501 atatttattt tttatgctat ttttctactc tatctaaagt atttgataca attaaactaa
    13561 taatcaatta taattttaca tagtttctta tctatagagt atttgctatc tgttgaatcg
    13621 tattttttaa atttaaaatc ccatatccct gcgatacatt tggatatgta tatatctcaa
    13681 gttttgtagc acccaatatt aaatatgttt ttaaaacttg tgtaaacaat gataatctcg
    13741 gtacattatc ctgtttttct aagtattcca tcaataaggc taaaacacct gtgactatag
    13801 aactgctcac tcctgttcct gttcctgtat tatatgttcc atttttatat gtggatatta
    13861 tatctacacc tgaagctact atatctggct taattcctct tcctctaatt ggtcctttcg
    13921 aagaaccaat ccacatacta tcagtcttat tgttaaatgt accaactgta attacatcat
    13981 cactagcagc atacatagtt atagtagcta ctgaatcagg gtctaaaaac cttgtgtctg
    14041 gagctatcaa atttttattt ggcaagtata tgtcatattc tccatttatt ataagttctg
    14101 aagtcaatct taaaatccat actccaggtt ttatatctct taatcttatc tccaaatttt
    14161 cttttccaga ggtaatatat ggataaataa atctcattgc ataagtagta ttttctaagt
    14221 taaattttcc tctatatata taaaagtctg gagaatacct tatatcatga ctaacttcac
    14281 ctgaaggaga tattatctgt gctcccactt tatctggacc attcgtattt agtgttatat
    14341 caagagcata gtcatctcca tcttgtatta ttacatcttg aacttctccc acactgctaa
    14401 atctgccaga ataatgaata tctgtattcc cttgatttcc tgcaccactc actactacca
    14461 caccagcact actcaatata ttaaaagtat ctagtattga agtagttgct acagcacttg
    14521 acttaactcc aatagtcaaa tttattatca gtggtttatt ttctgttctt gctatgttag
    14581 taacatacgt tatagctgct aaaaaatctg aaacactgta atttatcctt ccagcataat
    14641 aagtatctgt atatgatttt aatttaacta ctattaagtc tgattctgta gtaatacctc
    14701 tgtactgaga atttatcctt ccatttccaa ctaatatacc agaaactaaa gttccagtac
    14761 ctatattatc ttgactcaaa ctcccatcat ttctatttat ggctatattt aactcacttc
    14821 ttgtaaattc acttccaaaa ataaaacctt ctggaggtgg atttgtattt gcttcttggt
    14881 cccataaata taaaacttta ctagttccat catcatttat aaaatcagga tgcaaataat
    14941 ctatcccaga atctataact gctaataaaa ttcctctccc tgttatatca ttatatggat
    15001 tttcataaat ataatcagtt tcagctgctg ttgtaatggt ttctccatta tttacattat
    15061 tagttatttc aattagactg ctcattggtt cagattcttc ccaccaagca acttgtatta
    15121 tattatttaa aatagtttca tcaaaatcta aaggtacata tattactgca agctgactat
    15181 ttaaaaccat atacctattt attccatttt cttgtagggc agattctata tcaccttgat
    15241 aaattataca ataagatttt tccataaatc cctcctatct taaaacatca aacattcctc
    15301 taacatccaa gagcccatat ccagaatttg tatttggata tactgtgttt gaatcttttc
    15361 tagcaccagc ttgcataaaa gtttttattt tttgcacata tgcttggttt ggatatctac
    15421 catcaacaaa agtatattga aaatacattg cagcagcacc agctgcatgt gcacttgctg
    15481 ctgctgtacc agttatagtt gcatacgtgt tcccaggata agcagctatt atattaacac
    15541 ctggtgctac tatatctggt tttaacctgt cttcaatagt tggccctctt gatgaacttt
    15601 gccataaact accattaata gtattgtagg ctcctatggt tattaaatca tcttgaatcg
    15661 caggataatt tatagtgtaa aaagggtcta cctctctaaa tctagttcca ctttttaaaa
    15721 gttctctatt tggaaggtat aagttatatc ttcctgttat aatataaact cctactaatc
    15781 gaatcttcca tacacctctt tttgcattct ttaaagtaac attagtaaat tgctgtccag
    15841 aaaaagttgt tgggtatata tatgttatag aatattcagt cccttctaaa tcaaataaac
    15901 ctgttacttt attataattt gaaattccaa cacttttact ttcttcacca gtgggagata
    15961 ctattattac atcagcttta tctggtctat ttaaccaaag ttctaatgat aattcttcct
    16021 cgtcttcatt taactctaat tcaacttcaa cagaacctcc aacatatggt attattccag
    16081 atgtatgtgt ctgtgtatta ccctcatttc ctgctcctgc cgttatacat aaccctctag
    16141 taaagaacgc tttttcacta ttactcctat tggttaaacc tgctaggcta ctggtaccta
    16201 aagacatatt tataactaat ggtcttccaa gttcaaaagc ttttttatat gcatactgag
    16261 atgcagcaaa caacattgca ctattataaa aatcatctat cttgccgagt tttattatta
    16321 ttagctcaga atcttctgct atacctgcat attcactatt tacatttcca agccctgcac
    16381 atatcccact caacatagtt ccttgaccaa cttcatcctg agatagacta gggtcatttt
    16441 ctgcgatagc tcgatttata tcttctcgtg tatattctgt cccaatataa aaaccatcag
    16501 gaggagttcc ttcttttgtt tggtcccata aatatactat ttttgaagtg ccatctggat
    16561 aaataaaatc tgggtgtaga tagtctattc ctgtatctgc aattgatatt agagtccctc
    16621 ttcctgttat attaatatta ggattatttt taaagaaatt tacgcccatt tcttctgttg
    16681 caactacacc tccaaaagta cctcgattaa tttctccaag taatgtcatc tttgtagtcg
    16741 atacagttct tatgattgaa ggaagttgca aaactcgttg tatgctatta tagtctgtat
    16801 tatttataga tagtacacct aatgaatcac ttatcttaaa aaacctttga ctcataccta
    16861 acccagctag ttcttcttca aattcaggag tatggactat atctattcct gatagtattc
    16921 ctgattgtct acttgcattt ttacttatat aaatttcatt ctctaagtca ttatgtattt
    16981 gcatattata accatctata aacttataac tattttcctc atctttaaat gacttattaa
    17041 tacttctata tccaatatcc tctgtttcta aatcttgatt tatattagat agagtgtaca
    17101 aatctatatc tgataaattt aaaaaaccaa atcctgatga attatttgga taagattgat
    17161 tacttaatct ccttgctccc tttagaagta atgcccttaa tttctgtgaa tacaaaaata
    17221 aatcatttcc atttacaatt ccccattcca taaacaatga acaaacccct gtaacatgag
    17281 gtgtagccat gctagttcca gttaatgctc cacttgtacc tcctggtaaa aaagatacta
    17341 tatcttcacc tggagctaat aaatcaggtt taaaaacacc taattgtgta tctccttcac
    17401 cagaaaatat agatactata tctgttcttg aattaaaact acctactgtt ataactctac
    17461 ttgctgttcc aggaactgtt acagtaagct cttgagtagg aatcagaaat ctagtatttc
    17521 tatttagacc ttcagaagtt ggcaaatata tatttacatt accagttact atatctattg
    17581 gttcaaatac aattttccat aacccaggag ttatctgtgt atttgaactt aattgtagag
    17641 taactcttct tgtgagagaa tacggtgcta tagggtaaaa ataaccagtt attctagttt
    17701 cacccaaagt attccttatc tcacctgaag ttagagagat tgcttgtgtt tgattatttg
    17761 atgggtttac caaatgtaca ctaaaatcat caacaaaatc tggccatata tttatgttta
    17821 atatacgctc tccttcccca actataaact caacttcttc tgtaatatta ttttgaagcc
    17881 taatcctttt atgacctcct ttatctgcat tatttccagc tgctacaact atattgtttt
    17941 tccaaaataa acacatatca tctatatatt gttcaaataa agatgttcct ctatgtgaac
    18001 cttcattact tccataactt atatttaatg taacaggcat tcttaattct aatgccctat
    18061 ctaaaataaa tttaattgcc ctcataaact ctgtacttct cgaaaaaata tcggtctgta
    18121 tatttccaac tctaaccact attattctgg catcacttgc aatagttgca caaatacctg
    18181 caacatgtgt cccatgtaag ctagttgttg aaataggtat atacatactt ccatctattg
    18241 cattatttat gtcttcatta gtatataatg ttccttctct aaaaccttct ggtggatttc
    18301 cttgaataga ttggtcccaa taatataata tcttagacct tccatcacta tctctaaaca
    18361 caggtagagt ataatctatt cccgaatcaa ttataccaat tatagttcct tttccagtta
    18421 aaccagttct atttttaaat cctgttattc ctgtacttga aaaactttgc acatcctgag
    18481 tctgtaatat aaaaggcttt tctataaatt caatttctgg ataagttaaa agtatattta
    18541 catcttcttc attacttgat gttattattg catatgatga attaagtatc tctactgata
    18601 cacctaattc ttcttctaac ctcaatatat ctccattgta ttttacaatt aattcataat
    18661 ttattataat cacctcgact tctaaaatta ttattaatgt atatgttttg tgtgagtcta
    18721 aaatgtatta gactatataa ttttttaagt ttcagttata caatttataa tagatatatt
    18781 aaaaaaaata aataatgatg gtacaatttt gaataaatca taccatcatt tatatttact
    18841 ttatcttgaa accattaaat ttttcaatgc tttctcaaga ccttttacag tcaatggaaa
    18901 catattaaat tcacttttta tcattctttg agtttgatac caataattaa ttgaatccca
    18961 tccatctcta agttctggat tcatccatac aattttactg tactttctct taaacctttt
    19021 aagccactct ataccaggtg tgtaattata tggaccacga tagttaccac caatatgaag
    19081 caactcagaa ggcgacatag aagcatctcc aacaattata actttatagt ttttatctat
    19141 attttttaat atccattcag tattaataga tttacttaac caacattcag gtgttgtaaa
    19201 taatctatca taaatacagt tatggaaata atatatcttt acatctttaa aatgatttga
    19261 tttacttaca gactgaaata atgtattaca taaagtgcta taccctctca ttgaaccacc
    19321 tgaatccata agcaataaaa gcttcactgt attttttctt ggcttctcaa aaaataactt
    19381 taaatatcct gcattattac aagtctcttc aatagtctta tccaaatcaa gctctgtctt
    19441 tggagcatct attctagtag aaaattgacg aagtctcttt agtgcaactt gaaattgacg
    19501 catatttaaa acttcatcat ctctaaaatc tctgtatttt ctttctcctg caacttcaag
    19561 aacagctcta ccataagtag aatttccacc tatacgtata ccagtttgcc cttttcctga
    19621 atgtcctaac tctgaagtgc ctcctgtgcc tatccaataa ttaccaccat tatgaggaga
    19681 gtcttgttct tttattcgtt cctccaattt agctcttaat ttatcaagat ttatatttgg
    19741 attttgttct aatctttcaa actcttctaa atctatatct ggttttttaa gccaattcat
    19801 aatctcttct ggaatttctt cttggtgttc tataccttta aaatactcca aaaacactgc
    19861 atcaaactta tcaaaatcac tttcactttt tattaaaatc atcctgcaaa gatagtaaaa
    19921 atttgaaaag tttgaatagc acagtccttt atccaatgct tcaattaaag tcatccattc
    19981 atttaaagat acatttaatc ctcttgacct caataaataa aaaaattcaa taaacataat
    20041 tatccagctc ctattaacta taagtgtctt tgcatagatt caatatcctc attattctta
    20101 agcagtattc ctgcaaaagg aacttttttt tctatttttt caataggcat tccactcaaa
    20161 gttaatgctt gtatccagtc tattaactct gatgtactag gctttttttg tatgtccttt
    20221 aaacttctaa tccaataaaa agtagtcatt acttgttcca ataggtgttc ttctacttta
    20281 tcaaaatgta ctttaactat ttcttccatc atgtctctat caggaaattc tatataatga
    20341 aatatgcatc ttcttaaaaa agcatctgga agttcttttt ccgcatttga agttataata
    20401 actattggtc tttgtttagc tcttacagtt tcttttgtct catttatgta aaactccatt
    20461 ttatccaatt cccaaagcaa gtcatttgga aattctaaat ccgccttatc tatttcatct
    20521 attaaaagaa ttacttgttg atttgagcta aaggcctctc ctagtttacc atattttatg
    20581 tacttgctaa tatcatctac accttctcct ccaaattggc tatcataaag tctttgaaca
    20641 gtatcatata cataaagccc ttcttgtgct tttgtagttg attttatatt ccaaattact
    20701 aaatcttttt ttaattcatt tgaaattgct tgtgctagca tagttttacc tgttccaggt
    20761 tcgcccttaa tcaaaagtgg cttttcaaga gcaatagcaa cattaactga tgccatcaat
    20821 tctggtgata ctacataatc actacttcct ctaaagttag atatctcttt ttttatcata
    20881 aatcctactc cttttaaaca gtattttcta aatgtatata gactttatta ctatttttga
    20941 tataaaaata ataatataat acatttgtat agtattattc taaaattcta tatctaaata
    21001 aaatcacctc taaaatattt aatttttatc tttatt
//
LOCUS       DAEORM030000060        20803 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.060, whole genome shotgun sequence.
ACCESSION   DAEORM030000060 DAEORM030000000
VERSION     DAEORM030000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 20803)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20803)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 20803)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20803
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.060"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            370..681
                     /gene="rpsJ"
                     /locus_tag="KRH23_003030"
     CDS             370..681
                     /gene="rpsJ"
                     /locus_tag="KRH23_003030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HHS5226307.1"
                     /translation="MAKNEKIRIRLKSYDHKLLDFSAGKIVETAKKAGSQVSGPVPLP
                     TEKQVVTILRAVHKYKDSREQFEIRTHKRLIDIANPTPKTVDSLMRLDLPAGVDIEIK
                     L"
     gene            773..1402
                     /gene="rplC"
                     /locus_tag="KRH23_003031"
     CDS             773..1402
                     /gene="rplC"
                     /locus_tag="KRH23_003031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HHS5226308.1"
                     /translation="MKGILGKKVGMTQIFTDKGVVIPVTAVEAGPMVVTQIKTVDKDG
                     YNAIQIGFEDAKEKALNKPKKGHLAAANVLKKHLKEFRVDSVEGYTVGQEIKADVFEA
                     GAKIDVTGISKGKGFQGPIKRHGQSRGPETHGSRYHRRPGSMGACSYPGRVFKNKKLA
                     GHMGSVKVTVQNLEVVKVDADKNLILVKGAIPGAKGSVVTIKEAIKVSK"
     gene            1432..2055
                     /gene="rplD"
                     /locus_tag="KRH23_003032"
     CDS             1432..2055
                     /gene="rplD"
                     /locus_tag="KRH23_003032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HHS5226309.1"
                     /translation="MPKLNVLNVSGQNVGEIELSDSIFGVEVNGHVLYEVVKNQLANK
                     RQGTQSAKTRAEVRGGGRKPWKQKGTGRARQGSTRSVQWVGGGVAFAPKPRSYKYTLP
                     KKVRRLAMKSALSSKVQNSEVIVLDALNMDAPKTKEFAQILNNINAAKKALVVIADKN
                     DNVIKSARNIEGVQTALVNTMNVYDILKYDSFIITTDAVKKVEEVYA"
     gene            2055..2345
                     /gene="rplW"
                     /locus_tag="KRH23_003033"
     CDS             2055..2345
                     /gene="rplW"
                     /locus_tag="KRH23_003033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HHS5226310.1"
                     /translation="MTNPHDVIIRPVVTEHSMAEMGEKKYTFVVAKDANKTEIKKAVE
                     KVFGVSVDKVNTLNYDGKVKRMGRTQGRTSSFKKAVVKLTADSKEIEFFQGM"
     gene            2375..3205
                     /gene="rplB"
                     /locus_tag="KRH23_003034"
     CDS             2375..3205
                     /gene="rplB"
                     /locus_tag="KRH23_003034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HHS5226311.1"
                     /translation="MAIKKFRPTSPALRQMTVLVSDEITCNQPEKSLLVNLKKNAGRN
                     VHGRITVRHRGGGQKRKYRIIDFKRDKDGIPAKVATIEYDPNRTANIALLNYADGEKR
                     YILAPVGINVGDTILSGLGADIKPGNCLALKDMPVGTIIHNIELKPGKGAQLVRSAGV
                     SAQLMAKEGKNALLRLPSGEMRLVSINCKATIGQVGNIEHGNVVIGKAGRKRHMGIRP
                     TVRGSVMNPNDHPHGGGEGRSPIGRPSPVTPWGKPALGYKTRKKNKASNKLIVSRRTK
                     "
     gene            3240..3521
                     /gene="rpsS"
                     /locus_tag="KRH23_003035"
     CDS             3240..3521
                     /gene="rpsS"
                     /locus_tag="KRH23_003035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HHS5226312.1"
                     /translation="MSRSTKKGPFVHARLLKKIEAMNASGNKEVIKTWSRSSTVFPQM
                     VENTIAVHDGRKHVPVYITEDMVGHKLGEFVPTRTFKGHKDDEKSNKRK"
     gene            3553..3888
                     /gene="rplV"
                     /locus_tag="KRH23_003036"
     CDS             3553..3888
                     /gene="rplV"
                     /locus_tag="KRH23_003036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018590372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HHS5226313.1"
                     /translation="MEAKATAKYVRVSPRKAGQICDLVRGKNVDEALAILKFTPRGAA
                     SIIAKVVKSAKANAENNHEMDTEKLYIASIVANQGPTMKRFMPRAMGRATTIRKRTSH
                     IEVVVKEKK"
     gene            3911..4726
                     /gene="rpsC"
                     /locus_tag="KRH23_003037"
     CDS             3911..4726
                     /gene="rpsC"
                     /locus_tag="KRH23_003037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HHS5226314.1"
                     /translation="MGQKVNPHGLRVGVIKDWDSRWFATDKKEFGNLLLEDHNIRKFL
                     KKRLYSAGVAKIEIERSANKIKMDLHVAKPGVVIGRAGAGIEALKAELEKMTKKTIIV
                     NIVEVRSTDKNAQLVAENIALAIERRVAFRRAMKQAIQRAMKSGAKGIKVSASGRLGG
                     AEMARTEGYSEGNVPLQTLRADIDYGFAEADTTYGKIGIKVWICNGEVLPTRDGVNPR
                     EESRKSDRRDNKRDNRRNDRRGNDRRGNDNRGNYRGQRPQGGSRPQRTENKGN"
     gene            4762..5193
                     /gene="rplP"
                     /locus_tag="KRH23_003038"
     CDS             4762..5193
                     /gene="rplP"
                     /locus_tag="KRH23_003038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HHS5226315.1"
                     /translation="MLMPKRVKRRRVHRGSMAGQAHKGNKVTYGEFGLVALEASWITS
                     NQIEAARIAMTRYIKRGGKVWIKIFPHKPVTRKPAETRMGAGKGSPEYWVAVVKPGRV
                     MFELAGVSEDKAREAMRLAAHKLPIKCKFVKKEDLEVKGGE"
     gene            5195..5398
                     /gene="rpmC"
                     /locus_tag="KRH23_003039"
     CDS             5195..5398
                     /gene="rpmC"
                     /locus_tag="KRH23_003039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018590375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HHS5226316.1"
                     /translation="MKAKELRDLTSEELMNKLNDFKSELFSLRFQLATGQLENTARIK
                     FVKKDIAKVKTVLAERKLYETRA"
     gene            5422..5676
                     /gene="rpsQ"
                     /locus_tag="KRH23_003040"
     CDS             5422..5676
                     /gene="rpsQ"
                     /locus_tag="KRH23_003040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018590376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HHS5226317.1"
                     /translation="MERGRRKVRIGRVVSDKMDKTIVVAVEEFVRHPLYNKRVKRTKK
                     FKAHDEKNICNIGDRVKIMETRPLSKDKRFRLVEVVEKVK"
     gene            5702..6070
                     /gene="rplN"
                     /locus_tag="KRH23_003041"
     CDS             5702..6070
                     /gene="rplN"
                     /locus_tag="KRH23_003041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012158378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HHS5226318.1"
                     /translation="MIQQESRLRVADNSGAKELLCIRVLGGSKRRYGNIGDVIVATVK
                     SATPGGVVKKGKVVKAVIVRSKQGVRRNDGSYISFDENAAVIIKDDKTPVGTRIFGPV
                     ARELRDNEFMKIVSLAPEVL"
     gene            6094..6399
                     /gene="rplX"
                     /locus_tag="KRH23_003042"
     CDS             6094..6399
                     /gene="rplX"
                     /locus_tag="KRH23_003042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HHS5226319.1"
                     /translation="MRVKKGDTVVVIAGKDKGKKGSVLKVYPKTSKVLVEGVNVITKH
                     QKPSAMNQQGGIINKEAPIHISNVMPFDPETGKGVRVRYEVKDGNKVRVSAKSGKEL"
     gene            6429..6971
                     /gene="rplE"
                     /locus_tag="KRH23_003043"
     CDS             6429..6971
                     /gene="rplE"
                     /locus_tag="KRH23_003043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018590379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HHS5226320.1"
                     /translation="MASRLQEKYMKEVAPALMEKFGYKNVMEIPKLNKIVINMGIGDA
                     RENPKGLEKGVEELEMISGQKPVITKARKSVANFKLREGMPIGTKVTLRADKMFYFMD
                     KLVSVSLPRVRDFRGVNPNAFDGRGNYALGVKEQLIFPEIEYDKIDKVRGMDIIFVTT
                     AKTDEEARELLKLLGMPFSK"
     gene            6989..7174
                     /locus_tag="KRH23_003044"
     CDS             6989..7174
                     /locus_tag="KRH23_003044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HHS5226321.1"
                     /translation="MARKAMVVKQQRKQKYATREYTRCTICGRPHSVLKKFGICRICF
                     RELAYKGQIPGVRKASW"
     gene            7207..7605
                     /gene="rpsH"
                     /locus_tag="KRH23_003045"
     CDS             7207..7605
                     /gene="rpsH"
                     /locus_tag="KRH23_003045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012158382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HHS5226322.1"
                     /translation="MTMTDPIADMLTRIRNANVVKHETVDVPASNMKKELARILLEEG
                     FIRGYDVIEDGKQGIIRIQLKYGQEGERVITGLKKISKPGMRVYAANHEIPKVLNGLG
                     ISVISTSKGILTDKQARKENVGGEVICYVW"
     gene            7636..8178
                     /gene="rplF"
                     /locus_tag="KRH23_003046"
     CDS             7636..8178
                     /gene="rplF"
                     /locus_tag="KRH23_003046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HHS5226323.1"
                     /translation="MSRIGVKPIIIPAGVEVTIAEGNLVTVKGPKGTLTKQLSAELNI
                     KKEENTIMVERPTDNKKHRSLHGLTRTLLDNMVVGVNTGFEKKLELKGVGYRAQKQGK
                     KLVMNLGFSHPVEMEDPEGITVEAPNQTELIVKGIDKQLVGNYAAKIRAWRKPEPYKG
                     KGIKYVDEVIRRKEGKTGKK"
     gene            8214..8582
                     /gene="rplR"
                     /locus_tag="KRH23_003047"
     CDS             8214..8582
                     /gene="rplR"
                     /locus_tag="KRH23_003047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HHS5226324.1"
                     /translation="MLKKADKNANRLQRHKRVRRKISGTSQRPRLCVFRSANNIYAQI
                     IDDTKRVTLVAASSLEAEVKSAVNHTGNKEAAKKVGELVAKKAVEKGITEVVFDRGGY
                     LYHGRIQELAEGAREAGLKF"
     gene            8603..9112
                     /gene="rpsE"
                     /locus_tag="KRH23_003048"
     CDS             8603..9112
                     /gene="rpsE"
                     /locus_tag="KRH23_003048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HHS5226325.1"
                     /translation="MLRRKPIDAGQLDLQEKVVEVRRVTKVVKGGRNFRFAALVVVGD
                     ENGHVGIGAGKAMEVPDAIKKAVEDAKKNLIVVPIVGTTIPHEVRGHFGAGNILIMPA
                     VEGTGVIAGGPARAVLELAGLKDVRAKSLGSNNPRNMVNATIEGLNSLKTVEDIAKLR
                     GKKVEELLG"
     gene            9127..9312
                     /gene="rpmD"
                     /locus_tag="KRH23_003049"
     CDS             9127..9312
                     /gene="rpmD"
                     /locus_tag="KRH23_003049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HHS5226326.1"
                     /translation="MAKLQIKLVRSVIGTTPNQKKNVEALGLRKREQVVVKEDNAQTR
                     GMINKVSHLLEVTEIAE"
     gene            9345..9788
                     /gene="rplO"
                     /locus_tag="KRH23_003050"
     CDS             9345..9788
                     /gene="rplO"
                     /locus_tag="KRH23_003050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006440517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HHS5226327.1"
                     /translation="MKLHELKPAEGAVRAKRRLGRGTATGQGKTAGRGQKGQWSRSGG
                     GVRVGFEGGQMPLARRLPKRGFNNIFKKVYTEVNVEVLNRFENGTEITAELLKSTKTI
                     SKIGKDGIKILGEGNLEKALTVKAAKFTASAQEKIEKAGGKAELV"
     gene            9832..11100
                     /gene="secY"
                     /locus_tag="KRH23_003051"
     CDS             9832..11100
                     /gene="secY"
                     /locus_tag="KRH23_003051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HHS5226328.1"
                     /translation="MLSKLKQAWKIKAVRKKVMYTLMMIVIFRIGTTIPVPGIDTSII
                     QKMVGGNSLLSLYNMFTGGAFSNFSLFALGISPYITASIIIQLLTVGFESLAELQKSG
                     EEGKKKINKYTKYTALALAVVQALGITLGIVRSALISNSVFFITTVVITLVSASMLVM
                     WIGDKITEKGIGNGSSVIIFAGIISRIPTDVIKISQQVKSGEVAPWVIVILAVVILLT
                     VTGVTFIQEATRKIPVQYAKRVVGRKMYGGQSSHIPMKVNQSGVMPIIFASSLLAFPQ
                     TIAMFMGPNAQAFVQKYLSMATEQGFWTYRSIEILLIIFFSYFYTTVSFNTEDISKNM
                     KNNGGFIPGIRPGEPTMDYLNRILTRLTLAGATFLAIIAMVPALTTHYMKVNMSLAGT
                     SLLIVVGVALELKRQLESNLVMRSYQGFLK"
     gene            11117..11767
                     /locus_tag="KRH23_003052"
     CDS             11117..11767
                     /locus_tag="KRH23_003052"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016776 - phosphotransferase activity,
                     phosphate group as acceptor [Evidence IEA];
                     GO_function: GO:0019205 - nucleobase-containing compound
                     kinase activity [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HHS5226329.1"
                     /translation="MRIILLGPPGAGKGTQAAGIVEKYNIPHISTGDIFRKNIKEGTE
                     LGKKAKEYMDQGLLVPDELTVGLVTDRISQEDCKNGFMLDGFPRNVAQGEHLDIFLKN
                     AGISLDKVVNIEVDKSILVSRAVGRRICKSCGATYHVEFNPPKVEGVCDVCQGELYQR
                     ADDNEETVSKRIQVYLDETKPLVDYYSKQGIIADIKGDQAIDKVFEDIVAALGSGK"
     gene            11768..12514
                     /gene="map"
                     /locus_tag="KRH23_003053"
     CDS             11768..12514
                     /gene="map"
                     /locus_tag="KRH23_003053"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HHS5226330.1"
                     /translation="MIILKSKKEIELLREAGKIVADTHEVLRKAISPGISTLELDKIA
                     EENIRKYNAEPSFKGYGGFPGSICASINREVVHGIPGETILQEGDIVSLDIGAYYKGY
                     HGDSAKTHGVGMISEEDRKLIEVTRESFYEGIKFAKLGYRLSDISHAVQTHVEKHGFS
                     VVRDLVGHGVGANLHEDPQVPNYGLPGKGPRLREGMVIAIEPMVNAGRYHVKTLSDGW
                     TTVTIDGKKSAHYEHTIAITEHEPLILTKL"
     gene            12536..12805
                     /locus_tag="KRH23_003054"
     CDS             12536..12805
                     /locus_tag="KRH23_003054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KOW domain-containing protein"
                     /protein_id="HHS5226331.1"
                     /translation="MLSDNLSIGQVVKVSLGRDKGNLFFVVKIINNEYVLIADGKKRK
                     LDKPKLKKVKHLKKYNFINDEVRKRVVSGQEITDSFLRAELTKLN"
     gene            12843..13061
                     /gene="infA"
                     /locus_tag="KRH23_003055"
     CDS             12843..13061
                     /gene="infA"
                     /locus_tag="KRH23_003055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018590390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HHS5226332.1"
                     /translation="MAKKDVIELEGTVSEALPNAMFKVKLENGHEILCHISGKLRMNF
                     IRILEGDKVNVELSPYDLTRGRITWRKK"
     gene            13097..13210
                     /gene="rpmJ"
                     /locus_tag="KRH23_003056"
     CDS             13097..13210
                     /gene="rpmJ"
                     /locus_tag="KRH23_003056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HHS5226333.1"
                     /translation="MKVRPSVKPICEKCKVIKRKGKVMVICENPKHKQKQG"
     gene            13363..13734
                     /gene="rpsM"
                     /locus_tag="KRH23_003057"
     CDS             13363..13734
                     /gene="rpsM"
                     /locus_tag="KRH23_003057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012065416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HHS5226334.1"
                     /translation="MARIAGVDLPREKRAEIGLTYIYGIGKATANEILAKAEINPDTR
                     IKDLSEDQVNELRKVIDDDFLVEGDLRREIALNIKRLRDIKCYRGIRHAKGLPLRGQR
                     TKTNARTRKGPRKTVSRKKKK"
     gene            13770..14168
                     /gene="rpsK"
                     /locus_tag="KRH23_003058"
     CDS             13770..14168
                     /gene="rpsK"
                     /locus_tag="KRH23_003058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006440523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HHS5226335.1"
                     /translation="MAKPKKKVTRIRRRERKNIERGHAHIQSTFNNTIITLTDVHGNA
                     ISWASSGQLGFKGSRKSTPFASQMAAETAAKAAMEHGLKSVEVFVKGPGSGREAAIRA
                     LQATGLEVTMIKDVTPIPHNGCRPPKRRRV"
     gene            14200..14823
                     /gene="rpsD"
                     /locus_tag="KRH23_003059"
     CDS             14200..14823
                     /gene="rpsD"
                     /locus_tag="KRH23_003059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HHS5226336.1"
                     /translation="MARYTGASCRQCRREGMKLFLKGDRCYTDKCAIVKRNYAPGQHG
                     QGRKKVSNYGLQLREKQKVKRIYGVLETQFRNLYERAENMPGKAGENLLSLLERRLDN
                     VVYRMGLASSRKEARQLVTHGHFTLNGNKVDIPSLIVKVGDVIEVKEKSRSSAKFKNL
                     VEVNSRIAPKWLEANVEGMTAKVVGVPTREDIDLEIAEHLIIELYSK"
     gene            14901..15848
                     /locus_tag="KRH23_003060"
     CDS             14901..15848
                     /locus_tag="KRH23_003060"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed RNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HHS5226337.1"
                     /translation="MIEIEKPKVDIVELSEDYRYGKFVIEPLERGYGITIGNALRRIL
                     LSSLPGVAVNAIKIDGVLHEFSTIPGVKEDVTEIILTLKELSATIDGEGSRTLKIEAQ
                     GPCSITGADIICPPDVEILSKDLAIATLDDNAKLNMEIFVDKGRGYVSAEENKTENVP
                     IGVLPVDSIYTPVEKVSYHVENTRVGQKTDYDKLVLEVWTNGSINPQEGISLAAKVLV
                     EHLNLFIDLTEHVSSVEIMVEKEEDQKEKVLEMTIEELDLSVRSYNCLKRAGINTVEE
                     LANKSEDDMMKVRNLGKKSLEEVIQKLEELGLGLKPSEE"
     gene            15869..16210
                     /gene="rplQ"
                     /locus_tag="KRH23_003061"
     CDS             15869..16210
                     /gene="rplQ"
                     /locus_tag="KRH23_003061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HHS5226338.1"
                     /translation="MAKYRKLGRETAHRNLMLRNLVTCLLRSGRIETTVTRAKETRRM
                     AEKMITLAKRGDLHARRQVLAYVMDETVVNNLFTDLAPKYAERNGGYTRIIKIGPRKG
                     DAAEMAFIELV"
     gene            16330..17163
                     /locus_tag="KRH23_003062"
     CDS             16330..17163
                     /locus_tag="KRH23_003062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HHS5226339.1"
                     /translation="MDNIVKVNNISFEYITDEAKLKAIDNLSLDVKKGEFVAIIGHNG
                     SGKSTLSKNLNAILMPTEGNILIDDMDTKEEERLWDIRQTAGMVFQNPDNQIVATIVE
                     EDVAFGPENLGIEPKEIRRIVEESLKSVGMYDLRDRQPHLLSGGQKQRVAIAGIIAMR
                     PKCIIFDEATAMLDPSGRKEVMKTIKRLNKEENITVIHITHFMEEAVEADRVVVMEKG
                     KKILEGTPREVFSKIKMLKEIGLDVPCMTELSSLLIEEGINISSDILTVDEMVMELCQ
                     L"
     gene            17151..18017
                     /locus_tag="KRH23_003063"
     CDS             17151..18017
                     /locus_tag="KRH23_003063"
                     /EC_number="3.6.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HHS5226340.1"
                     /translation="MSIIVKNLTHIYNEGMPFASKALDDVSFEIKDRDFVGLIGHTGS
                     GKSTLIQHLNGLLKPSSGEIFINDFNITDKNLNLTEIRKRVGVVFQYPEYQLFEETID
                     KDIAFGPSNLGLEESEIHNRVKASMEAVGLDYEGFKDKSPFELSGGQKRRVAIAGVIA
                     MNPEVLILDEPTAGLDPGGRDEIFNLIKDLHEKKNMTIILSSHSMDDMAKLAKTLIVM
                     NHGSVEFMGTPREVFKSNASKLKDIGLDIPQVLELALKLREKGFDISEDILTLEEAKQ
                     EILKVVRGRGLC"
     gene            18011..18814
                     /locus_tag="KRH23_003064"
     CDS             18011..18814
                     /locus_tag="KRH23_003064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     component T family protein"
                     /protein_id="HHS5226341.1"
                     /translation="MLKDITIGQYYPTSSAIHKLDPRIKLVATIVFMVSIFVVNKFWP
                     YIVVLLCLLAMIKLANIPVKYIVKGVKPLKWIILFTFLINIFFLPGDEIWSFGFLAIT
                     KQGLRQAIFMAIRLIFLVVGTSLLTLTTSPIELTDGIERLLNPFKKIGLPVHELAMMM
                     TIALRFIPTLLDETDKIMKAQMSRGADFESKNLINRAKNLVPLLVPLFVSAFRRADEL
                     AMAMEARCYRGGHNRTKMRESVISRRDYMACVFQVVYLGAIIATRFIAI"
     gene            18846..19577
                     /gene="truA"
                     /locus_tag="KRH23_003065"
     CDS             18846..19577
                     /gene="truA"
                     /locus_tag="KRH23_003065"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HHS5226342.1"
                     /translation="MRNIKIKIQYNGKNYCGWQKQPDSLGIQGTIERAIYDITKEETS
                     LIGSGRTDSGVHAIGQIANFKINSGISIESIPMALNAKLPKDISVIEACEVNDDFHSR
                     YSAKGKTYKYLVYNSKFRNPILSEISYQVKYELDFDKMCSEAKSLLGTHDFKGFMSSG
                     SSVKDTVRTIYDIDISKKDDLITFEISGNGFLYNMVRIIVGTLVDMGRGRINEPFLDI
                     IQSKTRSRCGHTAPAQGLFLKKVHY"
     gene            19697..20128
                     /gene="rplM"
                     /locus_tag="KRH23_003066"
     CDS             19697..20128
                     /gene="rplM"
                     /locus_tag="KRH23_003066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HHS5226343.1"
                     /translation="MKSYIAKPADVQRKWYLVDAEGKTLGRLATEIATVLRGKHKPTF
                     TPHVDGGDFVVVVNAEKIVLSGKKLDQKYYRYHTGYVGGLKEISYRDMMDKKPEEVIS
                     HAVSGMLPKNKLRSRMMTRLRVFAGAEHTHAAQNPEVLNFK"
     gene            20157..20549
                     /gene="rpsI"
                     /locus_tag="KRH23_003067"
     CDS             20157..20549
                     /gene="rpsI"
                     /locus_tag="KRH23_003067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HHS5226344.1"
                     /translation="MANVQYYGTGRRKSSVARVRLVAGEGNILVNGRALENYFNYETL
                     IRDVKQPLVLTGNENKYDVIVKVEGGGFTGQAGAIRHGISRALLKADLDLRPALKKEG
                     FLTRDARMKERKKYGLKAARRAPQFSKR"
BASE COUNT         8308 a         2447 c         4328 g         5720 t
ORIGIN      
        1 ctttactaaa ctaatggatt taatataaaa aaaagagggg gtaactcctc tcttttttgt
       61 tttttgttga caagtagcgc taaagcatat atactaaact agtgccttga gacagattaa
      121 caatcaagtt taaggttatg atgttgtaat agaaaataaa attgaaaaaa acagaaaaaa
      181 aacttgaaaa aatgtaacag atgatataaa atataatagt gtgcttgaga gattaagaaa
      241 ataataatta aatcctagtg aaatacgaac tgatatcgat ttaaaagtta caacacaccc
      301 ggagcagtgt atcggtattg gttgtacgca acttgaaaat taaacacgtg ataaaggagg
      361 gaaaacaaaa tggctaagaa tgaaaaaata agaataagat taaaatcata tgatcacaaa
      421 ttattagatt tttcagcagg taaaatagtt gaaactgcta aaaaggctgg atcacaagtt
      481 tcaggacctg tgcctctacc aacagaaaaa caagttgtaa ctatattaag agctgtacat
      541 aagtacaaag actctagaga acaatttgaa ataagaactc ataaaagact aatcgacata
      601 gctaatccaa cacctaagac agttgactca ttaatgagat tagacttacc agcaggtgta
      661 gatatagaaa taaaattata agaaccccta agatattatc ctatagatga ttatcttaga
      721 atgattactc taaaagatgt aatccgctgt aagaattata ggaggtgcta atatgaaagg
      781 aatattaggc aaaaaagttg gtatgactca aatattcact gataaaggtg tagttatacc
      841 tgtaacagct gttgaagcag ggcctatggt cgttactcaa ataaaaacag ttgataaaga
      901 tggatacaat gctatacaaa taggttttga agatgctaaa gaaaaagctt taaacaaacc
      961 taaaaaagga catttagctg ctgctaatgt tttaaagaaa catttaaaag aatttagagt
     1021 agattctgta gaaggataca cagtaggaca agaaataaaa gctgatgtat ttgaagcagg
     1081 tgcaaaaata gatgttactg gaataagtaa aggtaaggga ttccaaggtc caataaaaag
     1141 acatggacaa agtagaggtc ctgaaactca cggttctaga taccacagaa gaccaggttc
     1201 aatgggagct tgttcttacc caggtagagt atttaaaaac aaaaaattag ctggacatat
     1261 gggaagcgta aaggtaacag ttcaaaactt agaggttgtt aaagtagatg ctgacaagaa
     1321 ccttatatta gttaaaggag ctataccagg agctaaaggt tcagtagtaa ctataaaaga
     1381 agctataaag gtttctaaat aatgactaac ctagagaaag gaggaataac aatgccaaaa
     1441 ttaaatgtac taaatgttag tggacaaaac gttggagaaa tagaattatc agattctata
     1501 tttggcgtag aagttaatgg acatgtttta tacgaagttg taaaaaatca attagcaaat
     1561 aagagacaag gaactcaatc tgctaaaact agagcagaag ttagaggtgg cggaagaaaa
     1621 ccttggaaac aaaaaggaac aggtagagca agacaaggtt ctacaagatc tgtacaatgg
     1681 gtaggtggag gagttgcttt tgcacctaaa ccaagaagct acaaatatac attacctaag
     1741 aaggtaagaa gattagctat gaagagtgct ttatcttcaa aagttcaaaa tagtgaagtt
     1801 atagtattag atgcattaaa catggatgct cctaagacta aagaatttgc tcaaatatta
     1861 aacaatataa atgctgctaa aaaagcttta gtagttatag ctgacaaaaa cgataacgta
     1921 ataaaatcag ctagaaatat agaaggtgtt caaactgcat tagttaatac tatgaatgta
     1981 tatgatatat taaaatacga ttcatttata ataactacag atgctgttaa aaaagtggag
     2041 gaggtgtacg cataatgact aatccacatg atgtaataat aagaccagtt gtaactgagc
     2101 acagtatggc tgaaatgggt gaaaaaaaat acacttttgt tgtggctaaa gatgcgaaca
     2161 aaactgaaat aaaaaaagca gtagaaaaag tattcggagt tagtgttgat aaagtaaata
     2221 ctttaaacta cgatggaaaa gttaaaagaa tgggtagaac tcaaggaaga acatcaagct
     2281 ttaagaaagc agtagttaaa ttaactgctg atagtaaaga aatagaattc ttccaaggaa
     2341 tgtagtatta taacaaacga aggagggaaa acagatggct ataaaaaagt ttagaccaac
     2401 ttctcctgcc ttaagacaaa tgacagtttt agtttctgat gaaataacat gtaatcaacc
     2461 agaaaaatct cttttagtta acttaaagaa aaatgctggt agaaacgtac atggtagaat
     2521 aactgttcgt catagaggtg gaggacaaaa aagaaaatat agaataatag attttaaaag
     2581 agataaagat ggtatacctg ctaaggttgc tactatagaa tatgatccaa acagaactgc
     2641 aaatatcgca ttattaaact atgctgatgg agaaaaaaga tatatattag ctccagttgg
     2701 aattaacgtt ggagatacta tattatcagg attaggtgct gatataaaac caggaaactg
     2761 tttagcatta aaagatatgc cagttggtac tatcattcat aatatagaat taaagccagg
     2821 aaaaggagct caattagtta gatctgctgg agtttctgca caattaatgg ctaaagaagg
     2881 aaaaaatgct ttattaagat taccatcagg tgagatgaga ttagtaagca taaactgtaa
     2941 agctactata ggtcaagttg gaaatataga gcatggtaac gtagttatcg gtaaagcagg
     3001 tagaaaaaga catatgggaa taagacctac tgtaagaggt tctgtaatga accctaatga
     3061 ccatccacac ggtggagggg aaggtagatc tccaataggt agaccatctc ctgttactcc
     3121 atggggtaaa ccagctcttg gatacaaaac tagaaagaaa aataaagctt caaataaact
     3181 aatagtatca agaagaacta agtagtaaat ttatttttgc tcggaaagga ggaatataaa
     3241 tgtcaagatc aactaaaaaa gggccttttg tccatgcaag acttttaaag aagatagaag
     3301 ctatgaatgc tagtggaaat aaagaagtta taaaaacttg gtcaagatct tcaactgtat
     3361 ttccacaaat ggtagaaaac actatagctg ttcatgatgg aagaaaacat gttccagtat
     3421 atataacaga agatatggtt ggacataaat taggtgagtt cgttcctact agaactttca
     3481 aaggacataa ggatgacgaa aaatctaata agagaaaata attaaattat gactaagaaa
     3541 ggaggaataa caatggaagc aaaagctact gctaaatacg tacgtgtatc accaagaaaa
     3601 gcaggccaaa tatgtgacct tgttagagga aagaatgttg atgaagcatt agcaatatta
     3661 aagtttactc caagaggagc agcttcaata atagctaagg ttgtaaaatc agctaaagct
     3721 aacgcagaaa acaatcacga aatggatact gaaaaattat atatagcatc aatagttgct
     3781 aatcaaggac caacaatgaa gagattcatg cctagagcta tgggtcgtgc aactacaata
     3841 agaaaaagaa cttctcatat agaggttgtt gttaaagaaa aaaaataatt aatagatagg
     3901 agggaaagta atgggtcaaa aggttaatcc acacggctta agggtcggtg ttataaaaga
     3961 ttgggactca agatggttcg ctactgataa aaaagagttc ggaaacttat tattagaaga
     4021 ccataatata cgtaaattct taaagaaaag attatactca gctggagttg ctaagataga
     4081 aatagaaaga tcagctaaca aaataaaaat ggacttacac gttgctaagc ctggtgtagt
     4141 tataggaaga gctggtgcag gaatcgaagc attaaaagct gaattagaaa aaatgacaaa
     4201 gaaaactata atagttaata tagtagaagt aagaagtaca gataaaaatg ctcaattagt
     4261 agctgagaat atagctttag ctatagagag aagggttgct ttcagaagag caatgaaaca
     4321 agctatacaa agagcaatga aatctggtgc taaagggata aaagtttctg cttcaggaag
     4381 attaggtgga gctgaaatgg ctagaactga aggttatagt gaaggaaatg tgccactaca
     4441 aactttaaga gcagatatag attatggttt cgctgaagct gatacaactt atggaaaaat
     4501 cggtataaaa gtttggatat gtaatggtga agttttacca actagagacg gtgtaaatcc
     4561 aagagaagaa agcagaaaga gcgatagaag agacaacaag agagataata gaagaaacga
     4621 tagaagagga aatgacagaa gaggaaatga taacagagga aactacagag gacaaagacc
     4681 tcaaggtgga tcaagacctc aaagaactga aaacaaagga aattaataat agttaggttc
     4741 aaggaaggag gaaaaatact catgttaatg ccaaaaagag taaagcgtcg tagagttcat
     4801 agaggaagca tggctgggca agctcataag ggtaataaag ttacttatgg tgagtttgga
     4861 ttagtagcat tagaagcttc ttggataact tctaatcaaa tagaagctgc cagaatcgcg
     4921 atgactagat atataaaaag agggggaaag gtttggataa aaatattccc tcataaacca
     4981 gtaacaagaa aaccagcaga gactcgtatg ggtgcaggga aaggttctcc agaatattgg
     5041 gtagctgtag ttaagccagg aagagttatg tttgaattag caggtgtttc tgaagataaa
     5101 gcaagagaag ctatgagact tgctgcacat aaattaccaa tcaaatgtaa atttgttaaa
     5161 aaagaagatt tagaagtaaa gggtggtgaa taggatgaaa gctaaagaat taagagattt
     5221 aacaagcgaa gagctaatga acaaattaaa cgacttcaaa agtgaattat ttagcttaag
     5281 attccaatta gctactggtc aattagaaaa tacagctaga ataaagtttg ttaagaagga
     5341 tatagcaaaa gttaaaactg ttcttgctga aagaaagtta tacgaaacta gagcttaatt
     5401 tggaaaggag gctttttaaa catggaaaga ggaagaagaa aagttagaat aggccgtgtt
     5461 gttagtgata agatggataa aacaatagta gtagctgttg aagaattcgt acgtcatcca
     5521 ctatataata aacgtgttaa gagaactaag aaattcaagg ctcatgatga aaagaatata
     5581 tgtaacatcg gagatagagt taaaataatg gaaactagac cattatctaa agataagaga
     5641 ttcagactag ttgaagttgt tgagaaagtt aagtagtttt tgaagaagga gggattacga
     5701 tatgatacaa caagaatcac gtctaagagt tgctgataac tcaggagcta aagaactttt
     5761 atgtatacgt gttctaggcg gaagtaaaag aagatatggt aacataggcg acgttatagt
     5821 tgctactgtt aaaagtgcaa cacctggtgg agttgtaaaa aaaggtaagg ttgttaaagc
     5881 tgttatagta agaagcaaac aaggcgtaag acgtaatgac ggaagctata tatcttttga
     5941 tgaaaatgct gctgttataa taaaggacga taaaactcca gtaggaactc gtatattcgg
     6001 gcctgttgct agagagttaa gagacaatga attcatgaaa atagtttctc ttgctccaga
     6061 agtactataa ttaaggaggt gcaataggac atgatgcgtg ttaaaaaagg tgacactgtt
     6121 gtagttatag caggtaaaga taaaggtaaa aaaggttcag ttttaaaggt atatcctaaa
     6181 actagcaaag tgttagttga aggtgtaaat gtaataacta aacatcaaaa accaagtgct
     6241 atgaaccaac aaggtggaat aataaataaa gaagccccaa tacacatatc taatgtaatg
     6301 ccatttgatc ctgaaacagg aaaaggcgtt agagtaagat atgaagtaaa agatgggaac
     6361 aaagtaagag tatcagcaaa gagcggaaaa gaattataat aaatattgct tgaaaggagg
     6421 gaccttaaat ggcttctaga ttacaagaaa aatacatgaa agaagttgct cctgctttaa
     6481 tggagaaatt tggatacaaa aacgtaatgg agatacctaa gttaaataaa atagttatta
     6541 acatgggtat aggtgacgct agagaaaatc caaaaggatt agaaaaaggc gttgaagaat
     6601 tagaaatgat atcaggacaa aagcctgtta taactaaagc tagaaaatct gttgctaact
     6661 tcaaattaag agaaggaatg ccaataggaa caaaagttac attaagagct gacaaaatgt
     6721 tctactttat ggacaaatta gtttcagttt ctttaccaag agttagagac tttagaggag
     6781 ttaaccctaa tgcttttgat ggtagaggaa attatgcttt aggagttaaa gaacaattaa
     6841 tattccctga aatagaatat gataaaatag ataaagtaag aggaatggat ataatatttg
     6901 ttactacagc aaaaactgac gaagaagctc gtgaattatt aaaattatta ggaatgccat
     6961 tttctaagta agcaaaggag ggattcccgt ggctagaaaa gcgatggttg ttaagcaaca
     7021 aagaaagcaa aagtacgcta ctagagaata cactagatgt actatatgcg gaagaccgca
     7081 ttcagttttg aaaaaatttg gtatatgccg tatatgcttt agagaattag cttataaagg
     7141 tcaaatacct ggtgttagaa aagcaagctg gtagaagctt gattagaatg gaaggagggc
     7201 aacaaaatga caatgacaga tccaattgca gatatgctta ctcgtataag aaatgctaat
     7261 gttgttaagc atgaaactgt agatgttcca gcttctaata tgaagaaaga attagctaga
     7321 atcttattag aagaaggttt cataagaggt tatgatgtta tagaagatgg aaaacaaggt
     7381 atcataagaa tacaattaaa gtacggacaa gaaggcgaaa gagttataac aggtcttaag
     7441 aaaatatcta agcctggaat gagagtttac gctgctaacc atgagatacc aaaagtatta
     7501 aacggattag gaatatcagt tatatctact tcaaaaggaa tattaactga caagcaagct
     7561 agaaaagaaa atgttggtgg agaagtaatc tgctacgttt ggtaattaat atgaacaatg
     7621 taaggaggtg cgaccatgtc aagaataggt gttaagccaa taataatacc agcaggtgtt
     7681 gaagttacta tagctgaagg aaatttagtt acagtaaaag gtccaaaagg aactttaact
     7741 aaacaattaa gtgctgagtt aaacataaaa aaagaagaaa atacaataat ggttgaaaga
     7801 ccaactgata ataaaaaaca tagatcttta cacggactaa ctagaacttt attagataat
     7861 atggttgtag gtgtaaatac tggtttcgaa aagaaattag aattaaaagg tgttggatat
     7921 agagctcaaa aacaaggaaa gaaattagtt atgaacttag gtttctctca tccagttgaa
     7981 atggaagatc cagaaggaat aactgttgaa gctccaaacc aaacagagtt aatagtaaaa
     8041 ggtatagaca agcaattagt agggaattat gctgctaaga taagagcttg gagaaagcca
     8101 gagccataca aaggtaaagg tataaaatac gttgatgaag taatcagacg taaagaagga
     8161 aaaactggta aaaaataata ccaaaactta aacgctagaa aggagtgagc taggtgttaa
     8221 aaaaggctga taaaaatgct aatagacttc aaagacataa gagagttcgt agaaaaataa
     8281 gcggtacttc tcaaagacca agattatgtg tatttagaag tgctaacaat atatatgctc
     8341 aaataataga tgacacaaaa agagtaactc tagttgctgc atcttcttta gaagcagaag
     8401 ttaagagtgc tgtcaatcat acaggaaaca aggaagcagc taagaaagtt ggagaattag
     8461 ttgctaaaaa agctgttgaa aaaggaatca ctgaagttgt atttgacaga ggtggatact
     8521 tatatcatgg aagaattcaa gaattagctg aaggtgctag agaagctggt cttaagttct
     8581 aatacgaagg agggaaaaat acatgctacg tcgtaagccg atagatgcag gacaacttga
     8641 cttacaagaa aaagttgttg aagtaagacg tgttactaag gttgtaaaag gtggtagaaa
     8701 tttcagattt gcagcattag tagttgttgg agatgaaaac ggacacgttg gtataggtgc
     8761 tgggaaagca atggaagtac cagacgctat aaaaaaagca gttgaagatg ctaagaaaaa
     8821 tctaatagta gtgccaatag ttgggactac aattcctcac gaagtacgcg gacactttgg
     8881 tgctggaaat atattaataa tgcctgctgt agaaggtaca ggagtaatag ctgggggacc
     8941 tgctagagcc gtacttgagc tagctggact aaaagacgtt agagctaaat ctttagggtc
     9001 taacaatcca agaaatatgg taaatgctac aatagaagga cttaattctc taaaaacagt
     9061 tgaagatata gctaaactta gaggtaaaaa agttgaagaa cttctagggt aaggaggtag
     9121 tgtaaaatgg ctaaattaca aataaagtta gttagaagtg ttataggaac tactcctaac
     9181 caaaaaaaga atgttgaagc gttaggatta agaaaaagag aacaagttgt tgtaaaagaa
     9241 gacaatgctc aaacaagagg tatgataaat aaagtaagtc acttattaga agtaactgaa
     9301 atagctgaat aatttttata aagtagtgca aggaggtgca atccatgaag ttacatgagt
     9361 taaaacctgc tgaaggtgca gtaagagcta agagaagatt aggtagaggt actgcaactg
     9421 gacaaggtaa aactgcagga cgtggacaaa aaggtcaatg gtctcgttct ggtggtggag
     9481 taagagtagg atttgaaggt ggacaaatgc cactagctag aagacttcct aagagaggtt
     9541 tcaataacat atttaagaaa gtttacacag aagttaatgt tgaagtttta aacagatttg
     9601 aaaatggaac agaaataact gcagaattat taaaatctac taaaactata agcaaaatag
     9661 gtaaagacgg aattaaaatc ttaggtgaag gtaatttaga gaaagcttta actgttaaag
     9721 ctgctaaatt tacagcttca gctcaagaaa aaatagaaaa agctggtgga aaagcagagt
     9781 tagtataata acctgctaat ctcctagcca gtacaggcgg ggtgaattag cgtgctgtca
     9841 aaattaaaac aagcttggaa gattaaagca gtaagaaaaa aagtaatgta tacacttatg
     9901 atgatcgtga tattcagaat aggtactact ataccagttc caggcataga cactagtatt
     9961 atacaaaaga tggtaggcgg caatagtcta ctttctctgt ataatatgtt tactggtgga
    10021 gcatttagta acttttcact atttgcttta ggtataagtc catatatcac tgcatcaatc
    10081 ataatacaac ttctaacagt aggttttgaa agtttagcag aacttcaaaa atctggtgaa
    10141 gaaggaaaga aaaaaatcaa taagtacact aaatatacag cactagctct agcagttgta
    10201 caagctttgg gaattacatt aggaattgta agaagtgctt taatatcaaa tagtgtgttt
    10261 tttatcacaa ctgttgtaat aacattagtt tcagcaagta tgttagtaat gtggattggg
    10321 gacaaaatta ctgaaaaagg aatcggtaat ggtagttcag taataatatt tgcaggtata
    10381 atatcaagaa tacctacaga tgttattaaa atatcgcaac aagttaaatc tggcgaagtt
    10441 gcaccttggg ttatagtgat tctagctgta gttatattac ttacagtaac aggagttaca
    10501 tttatacaag aagcaactag aaagatacct gtacaatatg ctaaaagagt tgttggaaga
    10561 aaaatgtatg gaggacaaag ttctcatata ccaatgaaag ttaaccagtc aggagttatg
    10621 cctataattt ttgctagttc acttttagct ttccctcaaa caatagctat gtttatgggt
    10681 ccaaatgctc aggcttttgt tcaaaaatac ttaagtatgg caacagaaca aggattttgg
    10741 acatatagat caattgagat tctacttata attttcttct catattttta tacaactgta
    10801 tcatttaata cagaagacat atctaaaaat atgaaaaata atggtggatt tataccaggt
    10861 ataagaccag gtgagcctac tatggattat ttaaatagaa ttttaactag attaacttta
    10921 gctggagcta ctttcttagc aataattgct atggtgccag ctcttacaac acattatatg
    10981 aaagtaaata tgagtctagc tgggacttca ttgctaatcg ttgttggagt tgctttggag
    11041 cttaagagac agttagagtc aaacttagtt atgagaagct atcaaggttt cttaaaataa
    11101 aatggagatg gataatatga gaataatatt acttggacct ccaggtgctg gtaaaggtac
    11161 tcaggcggca ggaatagtag aaaaatacaa tatacctcat atatcaacag gagatatatt
    11221 cagaaagaat ataaaagagg gaacagaact tggaaaaaaa gctaaagaat acatggacca
    11281 aggtttatta gtaccagatg agttaactgt aggtttagtt actgatagaa tatctcaaga
    11341 agattgtaaa aatggattta tgttagatgg atttccaaga aatgtagcac aaggagaaca
    11401 tttagatatc ttcttaaaaa atgctggtat atcactagat aaagttgtca atattgaagt
    11461 tgataagagt atattagtgt ctagagcagt tggtagaaga atatgtaagt cttgtggagc
    11521 tacttaccat gttgagttta atcctcctaa agtagaaggt gtatgtgatg tatgccaagg
    11581 agaattatat caaagagctg atgataatga agaaactgta tctaagagaa tacaagttta
    11641 tctagatgaa actaagcctt tagtagatta ttatagcaaa caaggtataa tagcagatat
    11701 aaaaggtgat caagcaatag ataaagtatt tgaagatatt gtcgcagcct taggaagtgg
    11761 aaaataaatg attatcttga aatcaaaaaa agaaatagaa cttttaagag aagcaggtaa
    11821 aatagttgct gacactcatg aagttttaag aaaagctatt tctccgggaa tatctacttt
    11881 agaattagat aaaatagctg aagagaatat aagaaaatac aatgcagaac cttcttttaa
    11941 aggatatgga ggttttccag gaagtatatg tgcttctatc aatagagagg tagtacatgg
    12001 tattccagga gaaactatat tacaagaagg tgacattgta agtttggata taggagccta
    12061 ttataaagga tatcatggtg attctgcgaa aactcacgga gtaggcatga tatctgaaga
    12121 agataggaaa ttgatagaag taactagaga aagcttctat gaaggaataa aatttgctaa
    12181 attaggatat agactttcag atatctcaca cgcagtacaa acacacgttg agaaacatgg
    12241 tttctcggta gttagagatt tagtgggtca tggagttgga gcaaatcttc atgaagaccc
    12301 acaagtacct aattatggac tcccaggaaa aggaccaaga cttagagaag gaatggttat
    12361 tgctatagag ccaatggtta atgcaggtcg ttatcatgta aagactctat cagatgggtg
    12421 gacgactgtt acaatagatg gaaaaaaatc agctcattat gagcatacga tagcaattac
    12481 tgaacatgaa cctttgatat tgacaaagtt gtaatttaaa aagtaggtga aaaaagtgct
    12541 atcagataat ttaagtatag gtcaagttgt taaagtttca ttaggacgag ataaaggaaa
    12601 tttattcttt gtagtcaaaa taattaataa tgaatatgta ttaatagctg atggaaaaaa
    12661 gagaaaactt gacaaaccta agttaaagaa agtgaagcac ttaaaaaaat ataattttat
    12721 taatgatgaa gttagaaaaa gagtagtatc tggacaagag attacagatt cttttttaag
    12781 agctgaactt actaagttaa attagataat ttaacttatt gaaatggagg gctggttagt
    12841 taatggccaa aaaagatgtt atagaattag aaggtacagt ttcagaagct ttacctaatg
    12901 ctatgttcaa agttaaacta gaaaatggac atgagatatt atgccacatt tctggaaagc
    12961 taagaatgaa cttcataaga attcttgaag gtgacaaggt gaatgttgaa ctttctccat
    13021 atgaccttac aagaggaaga attacttggc gtaagaagta gactatatta atatttagtc
    13081 taaggaggga ttaataatga aggttagacc atcagtaaaa ccaatatgtg aaaaatgtaa
    13141 agtaataaaa agaaaaggaa aagtaatggt tatctgtgaa aatccaaagc ataagcaaaa
    13201 gcaaggataa gaaattatta ctagcatttt gttaaatttt atagtataat actatattgt
    13261 gatgttaaca aaagaacgtt aaaatcgttg aacaatctgg cgtaggattg gcatatgatg
    13321 tgaagtttta aacactaaaa actatgtgta ggaggtgcga tcatggcaag aatagctggg
    13381 gtagatttac ctagagaaaa aagagcggag ataggcttaa cttatatata tggtataggt
    13441 aaagcaactg ctaacgaaat attagctaag gctgagataa atccagatac tagaataaaa
    13501 gatttatcag aagatcaagt taatgagtta agaaaagtta tagatgacga tttcttagtt
    13561 gaaggtgact taagaagaga aattgcttta aacataaaga gattaagaga tataaaatgt
    13621 tatagaggaa taagacacgc taaaggtctt ccattaagag gacaaagaac taagactaat
    13681 gctagaacta gaaaaggtcc tagaaaaaca gtatctcgta aaaagaaaaa ataaataaat
    13741 aataactaga tgaaggaggg aaaaggaaaa tggctaaacc aaaaaagaaa gttacacgta
    13801 ttagaagaag agaacgtaaa aatatagaac gtggtcatgc tcatatacaa tcaactttca
    13861 ataatacaat aataacttta actgacgttc acggaaatgc tatatcttgg gcaagttctg
    13921 gacaattagg attcaaagga tcaagaaaat caactccatt tgcatctcaa atggctgctg
    13981 aaacagctgc aaaagctgcg atggaacacg gactaaaaag tgttgaggta ttcgtaaagg
    14041 ggccaggttc aggaagagaa gctgcaataa gagctttaca agcaactgga ctagaagtaa
    14101 ctatgataaa agacgttact ccaatcccac ataacggatg cagaccacca aagagaagaa
    14161 gagtgtaatt aataagagta caataggagg tgtagataaa tggcaagata tacaggtgca
    14221 tcatgtagac aatgccgtag agagggaatg aaattattcc ttaaaggtga tagatgttat
    14281 acagacaaat gtgctatagt aaaaagaaac tatgctccag gtcaacatgg ccaaggaaga
    14341 aagaaagttt ctaactatgg attacaatta agagaaaaac aaaaagttaa aagaatatat
    14401 ggagttttag agactcaatt tagaaattta tatgaacgtg ctgaaaatat gcctggtaaa
    14461 gcaggtgaga acttattaag tttattagag agaagattag ataatgtagt ttacagaatg
    14521 ggactagcat cttctagaaa agaagctaga caattagtga ctcatggtca tttcacttta
    14581 aatggaaata aagtagatat accttcatta atagttaagg ttggagatgt tatagaagtt
    14641 aaagagaaat caagatcttc tgcaaaattc aaaaatttag tagaagttaa ctcaagaata
    14701 gctcctaagt ggttagaagc taatgtagaa ggaatgacag caaaagtagt tggtgttcca
    14761 acaagagaag atatagatct tgagatagca gagcacttaa tcatagaact ttactctaaa
    14821 taataagcac acttttaaaa attattttaa aattttgttt accctcagtg gattactgaa
    14881 ttttaaggag ggttttgtcc atgatagaaa tagaaaagcc aaaagtagat atagttgagc
    14941 ttagcgaaga ctatagatat ggtaagtttg ttatagagcc tctagaaaga ggatatggaa
    15001 taactatagg taacgcatta agaagaatat tattatcatc attaccaggt gtagcagtga
    15061 atgctataaa aatagatgga gttcttcatg aattttcaac aatacctggt gttaaagaag
    15121 atgttactga gataatatta actttaaaag agctttcagc aactatagat ggtgaaggaa
    15181 gtagaacact taaaatagaa gctcaaggac catgctctat cacaggtgca gatataatct
    15241 gtcctccaga tgttgaaata ttaagtaaag atttagcaat agctacatta gatgataatg
    15301 ctaaacttaa tatggagata tttgtagata aaggtagagg ttatgtttct gctgaagaaa
    15361 ataaaacaga gaatgttcca ataggtgttt tacctgtgga ttcaatatat actcctgttg
    15421 agaaggttag ttatcatgtg gaaaacacaa gagttggtca aaaaacagat tatgataaat
    15481 tagtactaga agtttggact aatggtagta taaatcctca agagggaata tcattagctg
    15541 caaaggtatt agttgagcat ttaaacttat ttatagactt aactgaacat gtaagtagtg
    15601 ttgaaatcat ggtagaaaaa gaagaagatc aaaaagaaaa agttcttgaa atgactatag
    15661 aagaattaga tttatcagtt agatcatata actgtttaaa gagagcggga attaatacag
    15721 ttgaagaatt agctaataaa tctgaggatg atatgatgaa ggttagaaac ctaggtaaga
    15781 agtcattaga agaggtaata caaaaactag aagaacttgg attgggatta aaaccaagtg
    15841 aagaatagcg agcaaaggag ggataagaat ggctaagtac cgtaaattag gacgtgaaac
    15901 agctcacaga aaccttatgt taagaaactt agtaacttgc ttactaagaa gtggaagaat
    15961 agaaactaca gtgactagag cgaaagaaac tcgtagaatg gctgaaaaga tgataactct
    16021 tgctaagaga ggagatcttc atgctagaag acaagtttta gcttatgtta tggatgaaac
    16081 agtagttaat aacttattca cagatttagc tccaaaatat gctgagagaa atggtggata
    16141 cactagaata ataaaaatag ggccaagaaa aggcgatgct gctgaaatgg cttttataga
    16201 attagtatag taaggaaagg attaggcttg atggcttaat ctttttttta tttttttgac
    16261 taaggtatga tataataatg tgtaaaatga tttttataag ttattgctta ctaaaaggag
    16321 tatgagttaa tggataatat agtaaaggta aataatattt cgtttgagta tattacagat
    16381 gaagcaaaac ttaaagcaat agataattta agcctagatg ttaaaaaagg agaatttgtt
    16441 gcgataatag gacataatgg ttctggtaag tctactttat ctaaaaactt aaatgctatt
    16501 cttatgccta ctgaaggaaa tattcttatt gatgatatgg atactaaaga agaagaaaga
    16561 ttatgggata taagacaaac tgcaggcatg gtatttcaaa atccagataa tcaaatagtt
    16621 gctactatag tagaagaaga tgttgcattt ggacctgaga acttaggtat agaaccaaaa
    16681 gaaataagac gaattgtaga ggagtcttta aaaagtgtag gtatgtatga tttaagagat
    16741 agacagcctc atttgttatc aggaggtcaa aagcaaagag ttgcaatagc aggaattatt
    16801 gctatgaggc ctaaatgtat aatatttgat gaagcaacag caatgttaga tccatctgga
    16861 agaaaagaag ttatgaaaac aataaaaaga cttaataagg aagaaaatat aactgttata
    16921 catataacgc actttatgga agaagcagta gaagctgata gagttgtagt tatggaaaaa
    16981 ggaaagaaaa tcttagaggg aactcctaga gaagtattca gtaaaataaa gatgttaaag
    17041 gaaatcggtt tagatgtacc ttgtatgaca gagttatcta gtttattaat agaagaaggt
    17101 ataaatatta gtagtgatat attaactgtg gatgagatgg tgatggaatt atgtcaatta
    17161 tagtaaagaa tttaacacat atatataatg aagggatgcc ttttgcaagt aaggcacttg
    17221 atgatgtttc ttttgagatt aaagatagag attttgttgg tcttataggt catacaggct
    17281 caggaaaatc tacattaata caacatttaa atggattact aaagccttcc tcaggagaaa
    17341 tatttataaa tgattttaat ataacagata aaaacttgaa tttaactgag attagaaaaa
    17401 gagtaggggt tgtatttcaa tatccagaat accaattgtt tgaagaaacg attgataaag
    17461 atatagcttt tggaccctct aatttaggct tagaggagtc tgagatacat aacagggtaa
    17521 aagcatcaat ggaagctgta ggacttgatt atgagggatt taaagacaaa tctccttttg
    17581 aattatctgg gggacaaaag cgtagagtag caattgctgg agttatagcc atgaacccag
    17641 aagttctcat attggatgaa ccaactgctg gtcttgaccc tggtggaaga gatgaaattt
    17701 ttaacttaat aaaagactta catgaaaaaa agaatatgac tataatacta tcatcacata
    17761 gtatggatga tatggcaaag ttagcaaaaa ctttaattgt tatgaatcat ggtagcgtag
    17821 aatttatggg aactcctaga gaagtattta aatcaaatgc tagtaaatta aaagatatag
    17881 gattagatat tccacaagtt ttagagcttg cattgaaatt gagagaaaaa ggctttgaca
    17941 tcagtgagga tatattgact ttagaagaag caaaacagga aatattaaaa gttgtgagag
    18001 gacgaggatt atgttaaaag atataactat agggcaatac tacccaacaa gttctgctat
    18061 tcataaatta gatccaagga taaagcttgt agcgacaatt gtatttatgg tatctatatt
    18121 tgtagtaaat aaattttggc cttatatagt agttttatta tgtttattag ctatgataaa
    18181 attggctaat ataccagtca aatatattgt taagggtgtt aaacctctta aatggattat
    18241 tttgtttaca tttcttataa atattttttt cttaccaggt gatgaaatat ggtcatttgg
    18301 atttttagct attacaaaac agggtctaag acaagcaatt tttatggcaa taagattaat
    18361 atttttagta gttggtacat cattgcttac tttaacaact tcaccaatag aattaactga
    18421 tggaatagag agattgttga atccatttaa gaaaattggt ttgccagttc atgaacttgc
    18481 aatgatgatg acaattgctt tacgttttat tcctacattg ttagatgaga cagacaaaat
    18541 aatgaaggct cagatgtcta gaggtgcaga ttttgaaagt aagaatctta taaatagagc
    18601 aaagaattta gtaccacttt tggtaccttt atttgtaagt gcatttagaa gagctgatga
    18661 attggctatg gccatggagg ccagatgtta cagaggtgga cataatagga ctaagatgag
    18721 agagtctgtt atatcaagaa gggattatat ggcatgtgta tttcaggttg tttatctggg
    18781 agcaattata gctactagat ttatagcaat ttaattaata agttatagat ataatgaggt
    18841 aaagtatgag aaatataaaa attaaaatcc aatacaatgg taagaattat tgtggatggc
    18901 aaaagcaacc tgattcttta gggatacaag gtacaattga aagggctata tatgatataa
    18961 caaaagaaga aaccagtctt atagggtctg gtagaactga ttcaggagtt catgctattg
    19021 gtcagattgc aaattttaaa attaattcag gtataagtat agaaagtata ccaatggcac
    19081 taaatgccaa gttgccaaaa gacatatcag ttatagaagc atgtgaagta aatgatgatt
    19141 ttcactccag atacagtgca aaaggtaaaa catataaata tttagtatat aatagcaagt
    19201 ttagaaatcc aatacttagt gagatatcat atcaagtaaa atatgaactt gattttgata
    19261 aaatgtgttc agaagcaaaa agtttattag gaacacatga ttttaaaggt tttatgagtt
    19321 ctggttcatc tgtaaaagat acagttagaa cgatatatga tattgatata agtaaaaaag
    19381 atgacttgat tacttttgag attagtggta atggtttttt atataacatg gtgaggatta
    19441 ttgttggaac acttgttgat atgggtcgtg gcagaattaa cgaaccattt ttagatataa
    19501 tacaatcaaa aactaggtca agatgtggac atacagctcc agcacaagga ttatttctca
    19561 aaaaagttca ttattaactt gacacaccag gctacatgta ttaaaatata tgagaatgtg
    19621 ttaataagtc cacttgcccc ggacttgaca taaacggtaa aaaaatttta tgaaaagtag
    19681 ttaaggaggg acagttatga aaagttatat agctaagcca gctgatgtac aaagaaaatg
    19741 gtacttagtt gatgctgaag gaaaaacatt aggtcgttta gcaacagaaa ttgcgacagt
    19801 attgagaggt aaacataaac caacatttac tcctcacgtt gatggtggag attttgttgt
    19861 tgtagtaaat gcagaaaaaa tagttttaag tggtaagaaa ttagatcaaa aatattacag
    19921 ataccatact ggttatgtag gtggattaaa agaaatatct tatagagata tgatggataa
    19981 gaaaccagaa gaagttatat cacatgctgt aagcggtatg ttacctaaaa ataaattaag
    20041 aagcagaatg atgactagat taagagtatt tgcaggtgct gagcacactc atgcagctca
    20101 aaatccagaa gttttaaact ttaaataaga ttaataggtg aaaggaggag tttataatgg
    20161 ctaacgttca atattatgga actggaagaa gaaaaagttc tgttgctaga gtaagactag
    20221 ttgcaggtga aggaaatata ttagtaaatg gaagagcatt agaaaattat tttaattatg
    20281 agacattaat aagagatgtt aaacaaccat tagttttaac tggtaatgaa aataaatatg
    20341 atgttatagt aaaagttgaa ggtggaggat tcactggaca agctggagct ataagacatg
    20401 gaatatctag agctttatta aaagctgatt tagatttaag acctgcttta aagaaagaag
    20461 gtttcttaac tagagatgca agaatgaagg aaagaaagaa atacggatta aaagcagcaa
    20521 gaagagctcc acaattctca aaaagataat tacttatttt tttggaaaag caaaatcctt
    20581 tatttactgt tattcagaaa gtattggtat tttaaaaatg ttgggttaag ttaattattg
    20641 atatataata aaataataag gtatcttatt aggatgtttt tcattaagaa gaacatcctt
    20701 tttattttga ctatttaata aaaaacatat gctaataaca tttaaatttt atttttataa
    20761 tattgtaatt taaaagttta tataaggtta tatattttaa gat
//
LOCUS       DAEORM030000061        20702 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.061, whole genome shotgun sequence.
ACCESSION   DAEORM030000061 DAEORM030000000
VERSION     DAEORM030000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 20702)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20702)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 20702)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20702
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.061"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            complement(220..954)
                     /locus_tag="KRH23_003068"
     CDS             complement(220..954)
                     /locus_tag="KRH23_003068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiocytidine biosynthesis TtcA family
                     protein"
                     /protein_id="HHS5226345.1"
                     /translation="MSIQKLLSKARKAIQDFDMIQENDKIAVGLSGGKDSLTLLHILK
                     SYQRFSPQNFELIAITLNTGGVDNSPLDKLCKEINVPFYEFQTDIKEIVFDIRQEKNP
                     CALCANLRRGALNDNAKKLGCNKVALGHHKDDAIETFLMSMFYEGRVNCFSPKTYLDR
                     QDLTVIRPMIYIEEYMTKKISKDSNYPIITNPCPANGHTRREYIKNLIANLNKEMPDF
                     KRNVFGALNNSEKLFIWDKEKIKNFK"
     gene            1079..1795
                     /locus_tag="KRH23_003069"
     CDS             1079..1795
                     /locus_tag="KRH23_003069"
                     /EC_number="3.4.17.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HHS5226346.1"
                     /translation="MKKFKLIGAIILVVFISVFISKDRLLKKDKDPIVAAQHDSEQDV
                     EANSQNKNHSNSISNILLVNKTNGISKNYTPENITKVNIPFVEEATEEEKQMAGEPAK
                     AVEDLVKQANSEGIQFLGSSAYRSYDTQLDTYTRRVKSQGREKADAYVAKPGYSEHQT
                     GLCIDLTNPERWFVGSTKEAKWLAENAHKFGFIIRYPEGKEDITGTAYEPWHIRYVGK
                     DAAEEIYSKGLTLEEYLQNK"
     gene            1929..2621
                     /locus_tag="KRH23_003070"
     CDS             1929..2621
                     /locus_tag="KRH23_003070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HHS5226347.1"
                     /translation="MNNTVLVVDDEKEIRDLIEIYLLNSGYNVIKAEDGKEALDILKK
                     ENIHLMILDIMMPKMDGIEVCRKVRESLNIPILMLSAKSEDMDKIQGIMTGADDYLTK
                     PFNPLELTVRVKSLIRRAYYFSGANNEDKDVIKVGVVIIDKEKHSVTVAGNEIILTSR
                     EFDILYLLANNKGRVYSTEEIFEKVWKEKYYQSNNTVMVHMSRIRDKIEKYTDGEKII
                     HTVWGVGYKIEK"
     gene            2611..3792
                     /locus_tag="KRH23_003071"
     CDS             2611..3792
                     /locus_tag="KRH23_003071"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HHS5226348.1"
                     /translation="MKNKSLLNHMFRPILDIIISCALTSMLILTSMYIIKSLYFNSGI
                     SVINQLVYQLRDLRSLIGESLFYPFLFTITSLAIYSMISYKRNKQIVDFIRKTNRKNQ
                     KLEIIKSAVNLMDEGNLEKSIDIEYDLDILKDKEKDDIDELAHKINNIVHQLRNITIE
                     ERQAQQTKTDLITNVSHDLRTPLTSIMGYLGVIEEGKYKDEVQMMYYVDIAYEKSKNL
                     NVLINDLFELTKMQNNTIKLNKIEINLVELLSQVVSQFEIYFKQEFMVSRINFNEEKL
                     IVKADPNKLVRAFENLITNAVKYGKDGHYVDIVTEKKEDMAVVKVINYGEPIPVLDLP
                     NIFDRFYRVEKSRNRNVGGSGLGLAITKNIVNLHDGEITVSSDKYQTVFEVQLPIIQS
                     A"
     gene            4074..4529
                     /locus_tag="KRH23_003072"
     CDS             4074..4529
                     /locus_tag="KRH23_003072"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HHS5226349.1"
                     /translation="MEKVESFKLDHTKVKAPFVRKCSVLDGVKGDKVTKFDLRFLQPN
                     VESFGTAAMHGLEHLLATYLRDTLDGVIDLSPMGCRTGFYLILWGDVDAKTVKIGLEE
                     ALKKVLESDKMPAATAIECGNYRDLSLFGAKEYAKDVLDKGFSLNIYGE"
     gene            4519..5244
                     /locus_tag="KRH23_003073"
     CDS             4519..5244
                     /locus_tag="KRH23_003073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008705 - methionine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="vitamin B12 dependent-methionine synthase
                     activation domain-containing protein"
                     /protein_id="HHS5226350.1"
                     /translation="MENNLIGREDISINQSEVLRYLQYRGQEIDKDLKYTIDECVAIT
                     KNKINPRYLSRIYPIKINKDNVVELEGTNLTLESKDVYELLKECNECVIMAATIGIDI
                     EKEIRRHSYSNLTKGLIIDSCGTTAIEEVCDIVQNNLEKVFLKQDKFITMRYSPGYGD
                     LPIEKNIDILNVLNAQKQIGLTITSNGIMIPRKSVVAIIGISNTRINKSKKEKSCENC
                     KNYRNCTYRKGANSCGNKTISEK"
     gene            5216..7597
                     /locus_tag="KRH23_003074"
     CDS             5216..7597
                     /locus_tag="KRH23_003074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homocysteine S-methyltransferase family protein"
                     /protein_id="HHS5226351.1"
                     /translation="MEIRQYLKNNILIFDGAMGTMLQQKGLKLGENPEVFGLQNPDKL
                     IEIHTAYLEAGSNVILTNTFGCNELKLDSKYTVEEVIDNAVLVARKAIENVDNTKPRY
                     VALDIGPIGEMLEPMGTLSFDKAYEIFKRQVLQGVKSGVDVIVIETMMDLYEAKVAVL
                     AAKENSDLPIFCTMTFDKGGRSFTGCMPECMVATIEGLGVDAIGVNCSLGPKQLLPIV
                     EKIASRATVPVMVQANAGLPNIVDGEAIYDVDAKEFFEGVKKFVEVGATIIGGCCGTN
                     PSFIKEISENINSVTKGCIEKIDKCVVCSPSKFVEVQSPTVVGERLNPTGRKSLQEAL
                     KNENVDYAINLGLEQVNAGAQILGVNVGLPEIDEKKLMPKLIREIQAVVDTPLQVDSS
                     NVEALEQGLRYYNGRTIVNSVNGKEESLESILPIVKKYGSCVVGLTLDEKGIPKKAEE
                     RFEIAKRIVNRAVSYGIKPKDIFIDCLSLTVSAQQEEAIETIKAITMVKTLGVKTILG
                     VSNISFGLPNRKALNASFLTLALGAGLDLAIINPNEYSMMEAINSFKILNNTDKGCIN
                     YINQYSNINNSKKSDSSTKIDKDLPLDILVERGLKDEAKNVTLNLLKEKDENYILDEI
                     LIPALDKVGKRYDSGDIFLPQLIQSAETVKVSLNTIKETLLSKSSNNVSKGKIIVATV
                     KGDIHDIGKNIVKIMLENYGYEVIDLGKDVPIEEVVEVAKKRNIKLVGLSALMTTTVQ
                     SMKDTIQALRDNEINAKVFVGGAVLTEEYAEEMGADYYSKDAKSAVEIAKLNF"
     gene            complement(7802..9031)
                     /locus_tag="KRH23_003075"
     CDS             complement(7802..9031)
                     /locus_tag="KRH23_003075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HHS5226352.1"
                     /translation="MNLNRNLEKYAELAIKVGVNIQPGQILLIKSPIECADFARNALK
                     EAYKCGAKNVYIEWSDEESTLIKYLYAPDEAFHEFPKWTAEQYVDIAKEGGAFLSVYA
                     QNPDLLKDVDPERVANFQKASGKALKEWRSYTLTDKCKWSIVSVPTKDWAKKVFPNLS
                     EDKAIEKLWDAIFKCSRVDGQDPIKAWEEHNENLKSKMDFLNKNNFKTLKYKSSKTDL
                     TLDLPKGHVWLSGASKDPNGISFNPNIPTEEIFGMPHKFKVNGTVYSTKPLVYGGNII
                     DNFFLTFKDGEIIDFSAEKGLDTLEKLIETDEGSHYLGEVALVPYNSPISNTDIIFYN
                     TLYDENASCHFAIGSAYKTCLEGGNNLKDEELDEHGVNDSLTHVDFMIGSADMDIIGE
                     TYDGKQIQIFKNGNWAF"
     gene            9632..10546
                     /locus_tag="KRH23_003076"
     CDS             9632..10546
                     /locus_tag="KRH23_003076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HHS5226353.1"
                     /translation="MELYEAIFYRKSVRNFSSKKIKKPLMEEIKRSCKNLEYLNEDLN
                     IKAHVVDRGHIIHFLMGKECKVKAPHYIVVTSDKGEDYLQNIGFATEGVVLRLTTLGI
                     ATCWLEGNLKREDILEFVDIGNKNFEEDEEDDLDYLAGIKTEEDDENKIENPYIIIAF
                     GYPAKNEELFRTRYARPDRKPVKDMINKINRNRKWKDILELTRRAPSVKNSQPWYFHK
                     DERGLHLFEKRPKKHCEDMNKVSLGVALRHFDIACIKNKIDVSYEKLPIRNKIGKSYF
                     ITVVEHVKPEEETQEENVTLEKEESQDE"
     gene            10570..11205
                     /locus_tag="KRH23_003077"
     CDS             10570..11205
                     /locus_tag="KRH23_003077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1847 domain-containing protein"
                     /protein_id="HHS5226354.1"
                     /translation="MYKCGKCNLRGCSNGNMDKLMKICPTREIELQQKAKQLYEEEEN
                     RKIAYNAGLVEAEGYCQYTRLKEIIEFAKKCGYKKIGIAFCIGLKREMQTVQKIFEHH
                     GFEVFSVICKNGAMPKSTIGLEASQTISKCSDEVMCNPIGQALFLNEAKVDLNVILGL
                     CVGHDTLAMKYMEAPITTLVVKDRVTGHNPVAAIYNAESYFEKKLFDKDEE"
     gene            11581..12297
                     /gene="pyrF"
                     /locus_tag="KRH23_003078"
     CDS             11581..12297
                     /gene="pyrF"
                     /locus_tag="KRH23_003078"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004590 - orotidine-5'-phosphate
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0044205 - 'de novo' UMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HHS5226355.1"
                     /translation="MINGKEKLIVAIDTDEFDKAKELIDRLEDSVDIFKVGLEQYVAT
                     KGKTIDYLKEKGKKIFLDLKFHDIPNTMKSAVRAAVRDNVWLMTIHVSDMEGMRQCAL
                     IAREEAERLNIEKPLVVGVTVLTSLSNQDLQDIGCNMTTEELAIKRAKLAKESGIDGV
                     VCSAQEVDKIVEACGTDFITVCPGIRPKSAEVGDQKRVVTPSDAIKKGAHYLVVGRPI
                     TKAENPRESAINIVREIENA"
     gene            12323..13366
                     /gene="carA"
                     /locus_tag="KRH23_003079"
     CDS             12323..13366
                     /gene="carA"
                     /locus_tag="KRH23_003079"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004088 - carbamoyl-phosphate synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0006541 - glutamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HHS5226356.1"
                     /translation="MKGKLILEDGTVFEGKAFGYLKEAIGEVVFNTSMAGYGELLTDA
                     TYYGQIVTMTYPLIGNYGINLEDVESNKVQVKGLIVREKSDNPNNFRCEMDIDTYLKQ
                     NKVIGLEGIDTRALTKIIRNNGTKRGIITLENVSLQDVQSKLEEHCNKDSVKNVTRKE
                     IENIKGTGAKVVVIDFGVKNSVLESLKACNCDITIVPAMTTVEEILNINPDLILLSNG
                     PGNPEDINDIVENIKKLIGKKPLTGIGLGHQILALALGGKTSKLVFGHRGGNHPVKCL
                     ETGKVFITSQNHGYNVSEMPENTEVTHINLNDNTIEGMRHKELPIYSVQYIPEYTTKE
                     DLDCIFNKFLALI"
     gene            13419..16625
                     /gene="carB"
                     /locus_tag="KRH23_003080"
     CDS             13419..16625
                     /gene="carB"
                     /locus_tag="KRH23_003080"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HHS5226357.1"
                     /translation="MPKLDSIKKTLVLGSGPIIIGQAAEFDYSGTQACQSLKEEGIEV
                     VLINSNPATIMTDKEVADKIYIEPLTIEFIEKIIEKERPDSLLAGMGGQTGLNLAVEL
                     YEKGILDKYGVKIIGTSVESIKKGEDRDIFREVMKEINQPVIVSDIVTDLQAGLDYAL
                     TIGYPVVVRPAYTLGGTGGGIADNEEELREILSHGLQLSPVGQVLIEKSIKGWKEIEY
                     EVIRDSKGNCIVVCNMENIDPVGVHTGDSIVVAPTQTLSNKECAMLKKASLDILNAVE
                     VQGGCNVQFALNPHSFEYAVIEINPRVSRSSALASKATGYPIAKVSSKIALGYTLDEI
                     ENAVTKKTYACFEPTIDYVVAKIPKWPFDKFKKANRKLGTKMMATGEIMSIGSNFEAA
                     ILKGIRSLETGKYSLVHTPSEERSIEELKKRVVVPDDERLFDLAEMIRRGYKVEMIEQ
                     ITGIDKWFINKFKWIVEQEEKLKVMKIEDLTKDYLLELKKKGFSDKGISDLMKISPEK
                     LYELRSLYNIKPAYKMVDTCAGEIDAISPYYYSTYEQYDEVVVSDKKKVIVLGSGPIR
                     IGQGIEFDYCSVHCVKSLRKMDIETIIINNNPETVSTDFDTSDKLYFEPLTEEEVLSI
                     IEKEKPEGVILQFGGQTAIKLAKFLHEKNIPILGTDFDDIDAAEDREKFDDLLERLDI
                     NRPKGKGVWSLNEGIEVANELGYPVLVRPSYVLGGQGMEITYNEEKLSQYLQDAFDRD
                     HKNPVLIDKYLTGREIEVDAICDKEDILIPGIMEHLERAGVHSGDSTTMYPSQNISDE
                     IKEKIVEYTKKIALDLNVLGMVNIQFIEFQNELYIIEVNPRASRTVPYISKVSGVPIV
                     DLATKCMLGAKLKDLGYGTGVYKEPKLVSVKVPVFSMSKLSKVEVSLGPEMKSTGEVL
                     GVGENLEEALYKGFLAAGRHMSDERGVVLATVNNHDKDEFIEIAKDMKELGYTFVATE
                     GTANSLRENGIEADIVNRVEESRPNILDAIRNKQVDIVINTPTKGNDSTRDGFKIRRT
                     AIEFSTEIMTSLDTLKALVEVKKKHLNKDELKVYNIAE"
     gene            16882..17931
                     /gene="carA"
                     /locus_tag="KRH23_003081"
     CDS             16882..17931
                     /gene="carA"
                     /locus_tag="KRH23_003081"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002845470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004088 - carbamoyl-phosphate synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0006541 - glutamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HHS5226358.1"
                     /translation="MKARLILEDGTVFIGKAFGYLEESVGEVVFNTSMIGYGEVLTDP
                     SYYGQIVTMTYPLVGNYGINLSSAESEKVQVKGFIVREKSDSPSNFRCEIDIDQYLKQ
                     NKVIGLEGIDTRALTKILRNNGTMKGIITLEDSKLEDVKHKLDKFSNTEAVRTVTRKE
                     VEHIKGNGPKVAVMDFGVKRNILRSFIARGCDITIFPATTSPEDVLSINPDLIFLSNG
                     PGDPEDLEDVIENIKALIGKKPIVGICLGHQLLALALGGKTAKLKFGHRGGNHPVKDL
                     EEGKVFITSQNHGYYVSEVPEQMKVTHINLNDNTVEGMRHEKLDVYSVQYHPEACPGP
                     KDNDYIFDKFLELVK"
     gene            18124..>20702
                     /gene="carB"
                     /locus_tag="KRH23_003082"
     CDS             18124..>20702
                     /gene="carB"
                     /locus_tag="KRH23_003082"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005951 - carbamoyl-phosphate synthase
                     complex [Evidence IEA];
                     GO_function: GO:0004088 - carbamoyl-phosphate synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0009220 - pyrimidine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase
                     (glutamine-hydrolyzing) large subunit"
                     /protein_id="HHS5226359.1"
                     /translation="MPKLDSIKKTLVLGSGPIIIGQAAEFDYSGTQACQALKEEGIEV
                     VLVNSNPATIMTDKEIADKIYIEPLTIEFIEKIIEKEKPDSLLAGMGGQTGLNLAVEL
                     HDAGILDKYNVKVIGTSIESIKKGEDRDLFREVMKEINQPVIVSDIVTNLEAGLEFAN
                     KIGYPVVVRPAYTLGGTGGGIADTEEELREILSHGLQLSPVGQVLLEKSIKGWKEIEY
                     EVMRDGNGNCITVCNMENVDPVGVHTGDSIVVAPSQTLSDEEYQLLRKASIDIINAIE
                     VQGGCNVQIALNPHSLEYAIIEINPRVSRSSALASKATGYPIAKVAAKIALGYTLDEI
                     ENAVTKKTYACFEPTLDYVVVKIPKWPFDKFRHANRKLGTKMMATGEIMSIGSNFEAA
                     ILKGIRSLETGKYSLVHAPSEGRTLEELKARVVVPDDERLFDLAEMIRRGYKVEMISE
                     ITGVDKWFINKFKWIVEQEEKLKVLKIEDLDKEYLHELKKKGFSDKGISDLMKISPEK
                     LYELRSLYNIQPVYKMVDTCGGEFEALSPYYYSTYEQYDEVVVSDKRKVVVLGSGPIR
                     IGQGIEFDYCSVHCVKSLRKMGIETIIVNNNPETVSTDFDTSDKLYFEPLTEEEVLNI
                     IEKEKPEGVILQFGGQTAIKLAKFLHEKNIPILGTDFRDIDAAEDREKFDDLLERLDI
                     NRPKGKGVWTINEGVEIAKELGYPVLVRPSYVLGGQGMEITYNEEKLIQYLDDAFDRD
                     HKNPVLIDKYLTGREIEVDAICDKEDILIPGIMEHLERAGVHSGDSTTMYPSQNISDE
                     IKEKIVEYTKKIALDLNVLGMVNIQFIEFQNELYIIEVNPRASRTVPYISKVSGVPIV
                     DLAT"
BASE COUNT         8402 a         2234 c         3805 g         6261 t
ORIGIN      
        1 gattaaacca gtagattgaa tgaattaata gattaaatta atatataaaa tatttaagtt
       61 ataattaatg tattagacaa aataaatact attaagaact attaaaatat agattaaaga
      121 taataacata taataaataa aaaagtaaga ttgtgtagat tatataaaga ttatttacaa
      181 ttaatacaat cttgcttttt tatttaaaaa ttttaattat tatttaaaat tttttatctt
      241 ctctttatcc catataaaca atttctcaga attatttaaa gcaccaaata catttctttt
      301 aaaatcaggc atctctttat ttaaattagc aataagattt tttatgtact ctctcctagt
      361 atgaccattt gcagggcagg gatttgtgat aataggatag ttagaatctt ttgaaatttt
      421 cttagtcata tactcttcta tgtaaatcat aggtcttata actgttaaat cctgtctgtc
      481 taggtatgtc tttggggaaa aacaatttac tctaccctca taaaacatag acattaaaaa
      541 tgtctcaatt gcatcatctt tatgatgacc aagagctact ttattacatc caagtttttt
      601 agcattatcg ttcaaagcac ctcttcttaa attagcacac aatgcacaag gattcttttc
      661 ttgtcttata tcaaatacaa tttcttttat gtcagtttga aattcataaa aaggaacatt
      721 tatttcttta cacaatttat ctagtggaga attatcaaca cctccagtat ttaatgttat
      781 ggctatcaat tcaaagtttt gtggagaaaa tctttgataa cttttaagta tatgaagtaa
      841 agttaaacta tcttttccac cagaaagtcc aaccgcaatt ttatcatttt cttgtatcat
      901 atcaaaatct tgtatagcct tacgagcttt acttagaagt ttttgtatag acattttatc
      961 accatccttt aaaaatatta aatttaagat ttatttaaga tttacttata aaatacttaa
     1021 gtcttatact ctaaaattaa cattatagca aacataacaa aaaggagaag atttaattat
     1081 gaaaaaattt aaattaatag gagccattat attagtagta tttataagtg tatttatatc
     1141 taaagataga ttacttaaga aagataaaga tccaatagta gctgctcaac atgattcaga
     1201 acaagatgtt gaggcaaatt ctcaaaataa aaatcactca aatagtatat caaatatatt
     1261 attggtaaac aagacaaatg gaattagcaa aaactatact cctgaaaata ttactaaggt
     1321 aaacatacct tttgttgaag aagcaacaga ggaagaaaaa caaatggcag gagaacctgc
     1381 aaaggcagtt gaagatttag ttaagcaagc taattcagaa ggaatacagt ttttagggtc
     1441 ttcagcatac agatcttatg atactcaact ggatacttat acaagaaggg taaaatctca
     1501 gggacgagaa aaggcagatg catatgtagc aaagcctggt tacagtgagc accaaactgg
     1561 actttgtatt gatttaacaa atccagaaag atggtttgtt ggaagtacaa aagaagctaa
     1621 atggttggca gaaaatgctc acaagtttgg atttataata agatatcctg aaggtaaaga
     1681 agatataaca ggtacagcat atgaaccatg gcatattaga tatgttggta aggatgctgc
     1741 cgaggaaatt tattcaaaag gattaacttt agaagaatat ttacaaaata aataatataa
     1801 atgtgtaaat aatttgtatt atattggaaa tttagaaatt aataaattta tagattacac
     1861 taactaaaat atagtataat tttatatgaa taaagctata tacaaagatt aagttaggat
     1921 gtgtaaaaat gaataataca gttcttgttg tggatgatga aaaggaaata agagacctta
     1981 tagagatata tcttttaaat agtggatata atgtaattaa agctgaagat ggaaaagagg
     2041 ctctagatat tttaaaaaag gaaaatattc atttaatgat attggatata atgatgccta
     2101 aaatggatgg gatagaagtt tgtagaaaag ttagagaaag tttgaatata ccaatactta
     2161 tgttaagtgc aaaatcagaa gacatggata aaatacaagg gataatgact ggtgcagatg
     2221 actatttgac aaaaccattt aacccacttg aacttactgt gagagtgaag tcgctgatta
     2281 gaagagcata ttattttagt ggtgctaata atgaagataa agatgtcata aaggttggag
     2341 tagtaattat agataaggaa aaacatagtg taacagtggc tggaaatgaa ataattttga
     2401 catcaagaga atttgatata ttatatttac tagcaaataa taaaggcaga gtatatagta
     2461 cagaagaaat atttgaaaag gtatggaaag agaaatatta ccaatctaat aatactgtaa
     2521 tggttcatat gagcagaata agagataaaa ttgaaaaata tacagatgga gaaaaaataa
     2581 ttcatactgt atggggagtt ggatataaaa ttgaaaaata aaagtttatt aaatcatatg
     2641 tttcgaccca tattagatat tataataagc tgtgctttaa cttcaatgct tattttaaca
     2701 agtatgtata taataaaatc attatatttc aatagtggga tatctgtaat taatcaactt
     2761 gtatatcagt taagagatct cagaagtctt ataggagaga gtttatttta tccattttta
     2821 tttacaatca catcattagc aatttattcc atgatatcgt acaagagaaa taagcaaatt
     2881 gtagatttta taagaaagac taatagaaaa aatcaaaaat tagaaatcat taaaagtgct
     2941 gtaaatttaa tggatgaagg taacttagaa aaaagtatag atattgagta tgatttagat
     3001 atattaaagg ataaagaaaa ggatgatatt gatgaactag cacataaaat caataatata
     3061 gtccatcaac ttagaaatat aactattgaa gagagacaag ctcagcagac aaaaacagat
     3121 ttaataacaa atgtgtcaca tgacttaagg acacctttga catccataat gggttattta
     3181 ggagtgatag aagaaggtaa gtataaagat gaagttcaga tgatgtatta tgttgatatt
     3241 gcatatgaaa aatcgaaaaa tttaaatgtt cttataaatg atttgtttga attgactaaa
     3301 atgcaaaata atacaataaa attaaacaaa atagaaataa atttagtaga gttattaagt
     3361 caagtagtat ctcaatttga aatttatttt aaacaagaat ttatggttag tagaattaat
     3421 tttaatgaag aaaaattaat tgtaaaagct gatccaaata aattggtaag agcatttgaa
     3481 aatcttataa ctaatgctgt gaaatatgga aaagatgggc attatgtaga tatagtcaca
     3541 gagaaaaagg aagatatggc ggttgtaaaa gtgataaatt atggggaacc aattccagtg
     3601 ttagatttac caaatatatt tgatagattt tatagagttg aaaaatcgag aaatagaaat
     3661 gttggaggtt ctggattggg tcttgcgatt acaaaaaata ttgtaaattt acatgatgga
     3721 gaaattactg tttcaagcga taaatatcaa actgtgtttg aagtacaact gccaataata
     3781 caatcagctt agttataaaa taaaagtacg attatgtgat ataaatatta taacaataaa
     3841 gtgtttacaa aaataaaaaa gtaatatata atttaagtca gtttaataag atacttatca
     3901 agagttaggg gagagagtta gctcagtgat cctataccaa ccttttatca ggtggtcctg
     3961 ctaacaacga tgagatgact tgaaataata tactcttctt atcaataata gataggaaga
     4021 gtttttttta gaattaatgt aacaaatttt aaagtataat ggaggattaa ataatggaaa
     4081 aagtagaaag ttttaagcta gaccatacaa aagtaaaagc tccttttgta agaaagtgta
     4141 gtgtacttga tggagtaaag ggagataaag taactaaatt tgacttgaga tttttacagc
     4201 caaatgtaga aagttttgga actgctgcta tgcacggttt agagcatctt ttagctactt
     4261 atttaagaga tacattagat ggtgtaatag acttatctcc aatgggatgt agaacaggat
     4321 tttatttaat actatgggga gatgtagatg ccaaaacagt taagattggt ttagaagaag
     4381 cattaaaaaa agttcttgaa tcagataaaa tgccagcagc tacagccata gaatgtggaa
     4441 actacagaga cttatcttta tttggggcaa aggaatatgc aaaagatgtt ttagataaag
     4501 gattttcttt aaatatatat ggagaataat ttaattggaa gagaagatat aagcataaat
     4561 caaagtgaag ttttaagata tttacaatac agaggtcaag agatagataa agaccttaaa
     4621 tatactattg atgaatgtgt agctataact aaaaataaaa taaatcctag atatttatct
     4681 aggatttatc ctattaaaat aaataaagat aatgttgtag aattagaggg aacaaattta
     4741 acattagaga gtaaagatgt atatgaactt ttaaaagaat gtaatgagtg tgtaattatg
     4801 gcagctacta tagggataga tatagaaaaa gaaataagac gacactctta ttcaaattta
     4861 acaaaaggac taataattga ttcatgtgga acaacagcaa tagaagaagt gtgtgacatt
     4921 gttcaaaata atttagaaaa ggttttttta aagcaagata aatttataac tatgcgatat
     4981 agcccaggat atggagattt accaatagaa aaaaatatag atatattaaa cgttttgaat
     5041 gctcaaaaac aaataggtct aacaattact tctaatggaa ttatgatacc gagaaagtca
     5101 gtagtggcta ttataggtat ttctaataca agaataaata aatctaagaa agaaaagtcg
     5161 tgtgaaaatt gtaaaaacta tagaaactgt acatatagaa aaggagcgaa ctcttgtgga
     5221 aataagacaa tatctgaaaa ataatatatt aatatttgat ggtgcaatgg gaacaatgct
     5281 tcaacaaaaa gggttaaagt taggtgaaaa tccagaagta tttggtcttc aaaatccaga
     5341 taaacttata gaaatacata cagcatactt agaggcaggt tcgaatgtaa ttcttacaaa
     5401 tacttttgga tgtaatgaac taaaattaga tagtaagtat actgtagaag aagtgattga
     5461 caatgctgtt ttggtggcta gaaaagctat agaaaatgta gataatacta aaccaagata
     5521 tgtagcttta gatattggtc ctataggaga aatgctagag cctatgggta ctttaagttt
     5581 tgataaagca tatgaaatat ttaaaagaca agtactacaa ggcgttaaat ctggagttga
     5641 tgtaatagta atagagacta tgatggattt atatgaagct aaagtagctg tattagcagc
     5701 aaaagaaaac tctgatttac ctattttctg tactatgaca tttgataaag gtggaagaag
     5761 ttttactgga tgtatgccag aatgtatggt ggctactata gaaggtctag gtgtagatgc
     5821 aataggagtt aattgttcat taggacctaa acaactttta ccaatagttg aaaaaatagc
     5881 atcaagagct acagtccctg ttatggttca agcaaatgca ggtcttccaa atatagttga
     5941 tggagaggct atatatgatg ttgatgcaaa agaatttttt gaaggggtta aaaagttcgt
     6001 tgaagttggt gctactataa taggtggatg ttgtggtacg aatccaagtt ttataaaaga
     6061 aatatctgag aatataaatt ctgttacaaa gggatgtatc gagaaaattg ataaatgtgt
     6121 agtatgttca ccatcaaaat ttgtggaagt acaatcgcct acagttgttg gagaaagatt
     6181 gaatcccaca ggtagaaaat ctctacaaga agcattaaaa aatgaaaatg ttgattatgc
     6241 tataaattta ggtttagaac aagtaaatgc tggagcacaa atacttggag taaatgttgg
     6301 tcttccagag attgatgaaa aaaaactaat gccaaaatta ataagagaga ttcaagcagt
     6361 agtagataca cctttacaag ttgattcttc caatgtagag gccttagagc aaggacttag
     6421 atattataat ggtagaacaa tagtaaactc tgtaaatggc aaagaggagt ctttagaaag
     6481 tatattacca atagttaaaa agtatggttc atgtgtggtt ggacttacac ttgatgaaaa
     6541 ggggatacct aaaaaggctg aagaaagatt tgaaatagca aaaaggatag ttaatagagc
     6601 agtttcttat gggataaaac caaaagatat atttatagac tgtttatcat taactgtttc
     6661 agcacaacaa gaagaagcaa tagaaactat aaaagctata acaatggtaa agacactagg
     6721 agtaaaaact atattaggtg tttcaaatat ttcatttggt cttccaaata ggaaagcgct
     6781 taatgcttct tttctaacat tagctttagg ggcagggctt gatttagcaa ttataaatcc
     6841 aaatgaatat agtatgatgg aagctatcaa ttcttttaaa atattaaata acacagataa
     6901 aggatgtata aactatataa atcaatatag taatataaat aattcaaaaa aatcagattc
     6961 atctacaaag attgataaag atttgccatt ggatatttta gttgaaagag gattaaaaga
     7021 tgaagcaaaa aatgtaacac tgaatctttt aaaagagaag gatgaaaatt atatattaga
     7081 tgagatttta attcctgctc ttgataaagt aggaaaaaga tatgatagtg gagatatatt
     7141 tttaccacaa ttgattcaat cagcagaaac ggtaaaagtt tcattaaata caataaagga
     7201 aactttatta agtaaaagta gcaataatgt atccaaagga aaaataatag ttgctacagt
     7261 aaaaggtgat atccatgata ttgggaaaaa tatagtaaaa ataatgctag aaaattatgg
     7321 atatgaggtt atagatttag gtaaagatgt ccctattgaa gaagtagtgg aagttgctaa
     7381 aaagagaaat ataaaattag taggattaag tgcacttatg actacgactg ttcaaagtat
     7441 gaaagataca attcaggcac tgagagataa tgagataaat gcaaaggtat ttgtaggagg
     7501 tgcagttttg acagaagaat acgctgaaga aatgggtgct gattattatt caaaggatgc
     7561 aaagtctgct gttgaaatag caaagttaaa tttttagcat ataaattaaa ataaaggttt
     7621 tactaaatag gatattttat atataatata aatataagtt ttagatactt atgtttaaaa
     7681 caataggaat taatctataa taatgagatt aattaatata aaaaatattt atcatcaaca
     7741 ttaaaaaggg ctgggaagtc tggtataact tccatcagcc ctttttagtt aaaatcatat
     7801 gttaaaaagc ccaattacca tttttaaaaa tctgtatttg ctttccatca taagtctcac
     7861 caataatatc catatcagca gaaccaatca taaaatctac atgtgttaaa ctgtcattta
     7921 caccatgttc atctaattct tcatctttta aattgtttcc accttccaga caagtcttat
     7981 aagcagaacc aattgcaaag tggcaagaag cattttcatc atatagagta ttataaaaaa
     8041 ttatatccgt attggatatt ggtgagttgt atggaacaag agcaacttct cctaaataat
     8101 gagagccttc atccgtttca ataagttttt ctagtgtatc taatcccttt tcagcagaga
     8161 aatctattat ttcaccatct ttaaatgtta agaagaaatt gtcaattatg tttccaccat
     8221 aaacaagagg ttttgtacta taaacagttc catttacttt aaacttatgt ggcattccaa
     8281 aaatctcttc agttggaata ttcggattaa aacttattcc attagggtct ttggatgctc
     8341 cacttagcca aacatgaccc tttggcaagt ctagagtcaa atcagttttt gaggatttat
     8401 attttaaagt tttaaagtta tttttattta gaaagtccat tttagattta agattttcat
     8461 tatgttcttc ccatgctttt atagggtcct gaccatctac tcttgaacat ttaaatatag
     8521 catcccacag tttttctatt gctttatctt ctgataaatt tggaaacact ttttttgccc
     8581 aatcttttgt tggcacagag actatactcc atttacattt atcagttaga gtgtaagaac
     8641 gccattcttt taaagctttt ccagatgcct tctgaaaatt tgcaactctt tcagggtcaa
     8701 catcttttaa taaatctgga ttttgggcat agactgataa aaatgcccca ccttcttttg
     8761 ctatatctac atattgttct gctgtccatt tggggaactc atgaaatgct tcatctggag
     8821 catataagta tttaataaga gtactttctt catcagacca ctctatataa acatttttag
     8881 caccacattt atatgcttct ttaagtgcat ttcttgcaaa atcagcacat tctattggtg
     8941 actttataag tagaatttga cctggctgta tgttaactcc aacttttatt gctaattcag
     9001 cgtatttttc taaatttcta tttaaattca tatttatcct cctatatttt taatattgaa
     9061 taacttataa agtattataa cattacttat gtttttaata ttgaacaact tataaaatat
     9121 tataacttta cttagatttt gggtcatatt caaaatattt atactttata gattgagaaa
     9181 taaaaaaaat attttaatta aaacaaatta tgaggataac aaacttattt aagcagtatg
     9241 ttttttgttg ataataatat taaagtagaa ataaaaatac ttttttagtg aaaagctata
     9301 caagaatacc gaaaaaaact tataatataa taatgagata gatatttata aatgaaaaaa
     9361 aatttttctg gcaaagctta attaaaaagg taatagctag tgttgttatt taaattagca
     9421 tagaaaatca aataaaaaaa ttatgctaat gtatagacat tgataaggta gaatttaagc
     9481 cttttgaatg ctatattaaa ctagagtaga tattcttatg aatttcaaaa tagggcagga
     9541 ggaaaaagga aataaaacta taaaaaatat aaagtattta tataaattta tagagtttat
     9601 acgtcagaag atttcagtta ggagggcata aatggagctt tatgaagcca ttttttatag
     9661 aaaatctgta agaaattttt ccagtaagaa gataaaaaag ccattgatgg aagaaataaa
     9721 aagaagttgt aaaaatttag aatacttaaa tgaagattta aatattaaag cacatgttgt
     9781 tgatagaggt catataatac attttttgat gggtaaggaa tgtaaagtaa aggcacctca
     9841 ttatatagta gttacatcag acaaaggtga ggactattta cagaatatag gatttgctac
     9901 agaaggtgta gttttgcgcc ttacaacatt gggaatagct acttgctggt tggaaggaaa
     9961 cttaaagaga gaagatatct tggaatttgt agatattggg aataagaatt ttgaagaaga
    10021 tgaggaagat gatttagatt atctagctgg aataaaaaca gaagaagatg atgaaaacaa
    10081 aatagaaaat ccttatataa taatagcatt tggatatcca gcaaaaaatg aagagttgtt
    10141 taggacgaga tatgctagac ctgatagaaa gccagtaaaa gatatgataa ataagataaa
    10201 taggaataga aagtggaaag atatcttaga attgacaaga agagctccat ctgtaaaaaa
    10261 ttctcaaccg tggtatttcc ataaggatga acgaggtctt catttatttg aaaagagacc
    10321 taagaaacac tgtgaagata tgaataaggt tagcttaggt gtagccttaa gacattttga
    10381 tatagcttgt ataaaaaata aaatagatgt ttcatatgaa aaacttccta taaggaataa
    10441 aataggaaaa tcatatttta taactgtagt cgagcatgtg aaaccagaag aagaaaccca
    10501 agaagaaaat gtaactctag aaaaagaaga atcgcaagat gaataaaatt ttggaagggg
    10561 atattggata tgtataagtg tggaaaatgt aatcttagag gctgttctaa tggaaatatg
    10621 gataaattaa tgaagatatg tccaactaga gaaattgaac tacaacaaaa agcaaagcaa
    10681 ctttatgaag aagaagagaa tagaaaaata gcttataatg ctggattagt tgaagcagag
    10741 gggtattgtc aatatactag actaaaagag attatagagt ttgctaaaaa gtgtggttat
    10801 aaaaagattg gcatagcatt ttgtattgga ctaaaaagag aaatgcaaac agtgcaaaaa
    10861 atatttgaac atcatgggtt tgaagtattt tctgttatat gtaaaaatgg ggcaatgcct
    10921 aagagtacaa ttggactaga agcatctcaa acaatatcaa agtgttcaga tgaggtaatg
    10981 tgcaatccaa taggacaagc tttattttta aatgaagcta aggttgacct taatgtaatt
    11041 cttggattat gtgttggtca cgatacttta gccatgaaat atatggaagc tcctataaca
    11101 actttagttg tcaaagatag agtaactggg cataatccag ttgctgcaat atataatgca
    11161 gaatcatatt ttgagaaaaa attgtttgat aaagatgaag aataattcaa agacttattg
    11221 acataaaaag caattagtgg tttaattata aaaaagataa aactttaaat tatcctatag
    11281 atacataaag ttatataaat aaagaaaaat attacagcta aattccttaa agtagtccag
    11341 agagactaaa gggttataga taatgttagt atataacctc tagtaaatct tctagaggtt
    11401 tttgatgagt ataaaataaa aatttaaata taataaagtc ttttaaacta gtccagagag
    11461 actgggaaag atatctcata gctaatgaat agagttatgt atagataaaa tccttatgcc
    11521 tcttttggtg tgaggatttt tttatgatta tttaggcttt attaaaaagg agatgtaaaa
    11581 atgataaatg gtaaagaaaa attgatagtt gcaattgata ctgacgaatt tgataaagct
    11641 aaagaactaa tagacagatt agaagatagt gtagacatat ttaaggtagg gctagagcaa
    11701 tacgttgcca caaaaggtaa aacaatagat tatcttaaag aaaaaggtaa aaaaatattt
    11761 ttagacctta aattccatga tataccaaat actatgaaaa gtgcagtgag agctgcagtg
    11821 agagataatg tttggttaat gacaatacat gtatcagata tggaaggaat gagacaatgt
    11881 gcactaattg ctagggaaga agcagaaaga ttaaatatag aaaagccatt agtagttgga
    11941 gtaacagttt taacttcatt aagcaaccaa gatttacagg acataggatg taatatgaca
    12001 acagaagagt tagctataaa gagagctaaa ctggcaaaag aatcaggaat agatggggtt
    12061 gtttgttcag cgcaagaagt agataaaata gtagaagcat gtggaactga ttttataaca
    12121 gtttgcccag gaataagacc taaatcagca gaggttggag accaaaaaag agttgtaact
    12181 ccatcagatg caataaaaaa aggtgctcat tatttagttg ttggaagacc tataacaaaa
    12241 gcagaaaatc caagagaatc agctattaat attgtaagag aaatagaaaa tgcttagata
    12301 aaatatttgg gaggtagctt acatgaaggg gaaattaatt ttagaagatg gaacagtatt
    12361 tgaaggaaaa gcatttggat atctaaagga agctattgga gaagttgtat ttaatacttc
    12421 aatggctggg tatggagaac tattgacaga tgcaacttat tatggacaaa tagttactat
    12481 gacttatcca cttataggaa actatggaat aaatttagaa gatgttgaat caaataaggt
    12541 gcaagtaaaa ggacttattg taagagaaaa aagtgataac ccaaataatt ttagatgtga
    12601 aatggatata gacacatatc taaagcaaaa taaggtaata ggacttgaag gaatagatac
    12661 aagagcatta actaaaatta ttagaaacaa tggaactaag agaggaatta taactttaga
    12721 aaatgtatca ttacaagatg ttcagtctaa attagaagag cattgtaaca aagattcagt
    12781 aaaaaatgtt acaagaaaag aaattgaaaa tataaaaggt actggagcta aagttgtagt
    12841 tatagacttt ggtgttaaaa atagtgtact agagtctctt aaggcttgta actgtgatat
    12901 aactatagta ccagcaatga ctacagtaga agaaatttta aatataaatc ctgacttaat
    12961 cttattatct aatggcccag gaaatccaga ggatataaat gatatagttg aaaatataaa
    13021 aaaattaata ggcaaaaagc cattgacagg aataggttta ggacatcaaa ttttagcatt
    13081 ggcattagga ggaaagactt caaagcttgt atttggacat agaggaggta atcacccagt
    13141 taaatgttta gaaactggaa aggtatttat aacttctcaa aatcatggat ataatgtttc
    13201 agaaatgcca gaaaatacag aagtaactca cataaattta aatgacaata ctatagaagg
    13261 aatgagacat aaggaattac caatatatag tgttcagtac attccagaat acacaacaaa
    13321 agaagattta gattgtatat ttaataaatt cttagcatta atatagattt agtattattt
    13381 acagatagta aaaaccattt agataaggag aaaaatttat gcctaaatta gatagtataa
    13441 agaaaacttt agtattaggg tcaggaccaa taataatagg tcaagctgca gagtttgact
    13501 attcaggaac acaagcttgc cagtctttga aagaggaagg aattgaagtt gtattaataa
    13561 atagtaatcc agccactata atgactgata aagaagtggc agataaaata tatatagaac
    13621 cattaacaat agaatttata gaaaaaataa tagaaaaaga aagaccagac agtttacttg
    13681 caggtatggg tggacaaaca gggctaaatc tagcagttga actttatgaa aaaggcatac
    13741 tagataaata tggagtaaag ataataggta cttcagtaga atctatcaaa aaaggtgaag
    13801 atagagatat atttagagaa gtaatgaaag aaataaatca gcctgtaata gttagtgata
    13861 tagttacaga tttacaagca ggtcttgatt atgcacttac aattggatat ccagtagttg
    13921 taagaccagc atacacacta ggtggaactg gtgggggtat agctgataat gaggaagaat
    13981 taagagaaat actttcacat ggtctacaat taagtcctgt tggacaagta ttaattgaaa
    14041 agagtataaa aggttggaaa gaaatagaat atgaggtaat aagagattca aagggaaatt
    14101 gtatagttgt atgtaatatg gaaaatatag acccagtcgg agttcataca ggagacagta
    14161 tagttgttgc tccaactcaa actttaagta acaaagaatg tgcaatgctt aaaaaagcat
    14221 ctttagatat attaaatgca gtagaagttc aaggtggttg taacgttcaa tttgcactta
    14281 atccacatag ttttgaatat gcagttatag agataaatcc aagagttagt aggtcatcag
    14341 ctttagcatc aaaagctaca ggatatccaa tagctaaagt ttcatcaaaa atagctttag
    14401 gttatacttt agatgagata gaaaatgcag taactaaaaa aacttatgct tgttttgaac
    14461 caactataga ttatgtggtg gcaaaaatac caaaatggcc ttttgataaa tttaaaaaag
    14521 caaatagaaa attaggaact aagatgatgg caactggtga aattatgagt ataggaagta
    14581 attttgaggc tgctattctt aaagggataa gatcacttga aacaggaaaa tattcattag
    14641 ttcacacacc atctgaggag agaagcattg aggaattaaa gaaaagagtt gtagtacctg
    14701 atgatgagag actatttgat ttagctgaaa tgataagaag aggctataaa gtagaaatga
    14761 tagaacaaat tacaggtata gataaatggt ttataaataa atttaaatgg atagtagagc
    14821 aagaagaaaa attaaaagtt atgaaaattg aagatttaac taaagactat cttcttgaat
    14881 taaagaaaaa gggattctct gataaaggta tatctgacct aatgaagata agtccagaaa
    14941 aattatatga attgagaagt ctatacaata tcaaaccagc atataaaatg gttgatactt
    15001 gtgcaggtga gatagatgct atatctcctt actattattc aacttatgag caatatgatg
    15061 aggtagttgt tagtgataag aaaaaggtga tagtattagg ttctggtcca ataagaatag
    15121 gtcaaggtat agaatttgac tattgttcag ttcactgtgt aaaatcttta agaaaaatgg
    15181 acatagaaac tataatcata aacaataacc ctgaaactgt aagtacagac tttgatacat
    15241 cagataagct gtattttgaa ccattaacag aagaagaagt tttaagtata atagaaaaag
    15301 aaaaaccaga aggtgtaata ctacagtttg gtggacaaac agctataaaa ttggctaaat
    15361 ttttacatga aaaaaatata cctatactgg gaactgattt tgatgatata gatgcagcag
    15421 aagatagaga aaaatttgat gatttactag agagactaga tataaataga ccaaaaggaa
    15481 agggtgtatg gtcacttaac gaaggtattg aagttgctaa tgagttaggt tatccagtat
    15541 tagttagacc atcttatgta cttggtggtc aaggtatgga aataacttat aacgaagaaa
    15601 aattatctca atacctacaa gatgcatttg atagagacca taaaaatcca gtacttatag
    15661 ataaatatct aactggtaga gaaatagaag tagatgctat atgtgataag gaagatatat
    15721 tgatacctgg tataatggaa catttagaaa gagctggagt tcactctgga gatagtacaa
    15781 caatgtatcc aagtcaaaat atatctgatg aaataaaaga aaagatagta gaatacacta
    15841 aaaaaatagc tttagacctt aatgtgcttg gtatggttaa tatacagttt atagaatttc
    15901 aaaatgaatt atatataatt gaagttaacc ctagagctag tagaacagtt ccgtatataa
    15961 gtaaagtaag tggagtacca atagttgact tggctactaa gtgtatgtta ggagctaaat
    16021 taaaggattt aggatatggt acaggagttt acaaagagcc aaaattagta tcagtaaaag
    16081 taccagtatt ctcaatgtct aaattatcta aagttgaagt aagtctagga cctgaaatga
    16141 agtctacagg agaagtccta ggtgtaggag aaaatttaga agaagcctta tataaagggt
    16201 tcttggcagc aggtagacat atgtctgatg aaagaggagt agtacttgct actgtaaata
    16261 atcatgataa agatgagttt atagagatag caaaagatat gaaagaatta ggatatactt
    16321 ttgttgctac agaaggaaca gctaatagct taagagaaaa tggaatagag gctgatatag
    16381 taaatagagt agaagaatct agaccaaaca tattagatgc tataagaaat aaacaagttg
    16441 atatagtaat aaatacacca actaaaggaa atgactctac aagagatgga tttaagataa
    16501 gaagaacagc tattgaattt tctactgaaa taatgacatc tttggataca ctaaaagctt
    16561 tagtagaagt taagaagaaa catttaaata aagatgagtt aaaagtttac aatatagctg
    16621 aatagaaatt aagttgattg tatagtttaa gaatttaatt attaaataaa aaaaagaggt
    16681 tatttttttt aggagttttt acttttgaga taacttcttt tttttaagaa atttgtagta
    16741 taatagaaaa agataaaaaa taaatgtaaa taagtataaa actagaatgt aaaagtgaaa
    16801 aatagatata gatatttaaa agcttatatt tagttaatgt tctttagttt gtctaaagag
    16861 aattatagga ggtactgtag tatgaaagca aggttaatat tagaagatgg aacagttttt
    16921 ataggaaagg catttggata tttagaagaa agtgtaggag aagtagtatt taatacttcg
    16981 atgataggat atggtgaagt tttaacagac ccttcttact atggtcaaat agttactatg
    17041 acttatcctc ttgtaggaaa ttatggtata aatttatcat cagcagagtc tgaaaaagtt
    17101 caagtaaagg gattcatagt aagggagaaa agtgattctc caagtaattt tagatgtgaa
    17161 attgatatag accaatattt aaagcaaaat aaagttatcg gacttgaagg aatagataca
    17221 agagctttga ctaagatact tagaaataat ggaaccatga aaggtataat tacattagaa
    17281 gacagtaaat tagaagatgt taaacataaa ttggataagt tttcaaatac agaagcagtt
    17341 agaactgtta caagaaaaga agtagagcat ataaagggaa atggtccaaa agtggctgtt
    17401 atggattttg gagtaaaaag aaatatatta agatcattta tagctcgtgg atgtgatata
    17461 acaatatttc cagctacaac atctccagaa gatgtattga gtataaaccc tgacttaata
    17521 ttcttgtcaa atggacctgg agacccagaa gacctagaag atgttataga aaatataaaa
    17581 gctcttattg gtaaaaaacc tatagttgga atatgcttag gacatcaact tttagcttta
    17641 gctcttggag gaaaaactgc taaacttaaa tttgggcata gaggtggaaa tcatccagtt
    17701 aaagatttag aagaaggaaa agtatttata acttctcaaa atcatggtta ttatgtttca
    17761 gaagttcctg aacaaatgaa agtgacacat ataaatttaa atgataatac tgttgaagga
    17821 atgagacatg agaaactaga tgtatacagt gttcaatacc atcctgaagc ttgcccagga
    17881 ccaaaagata atgactatat ttttgataaa tttttagaat tagtaaaata aataacatta
    17941 gaatagctaa ctaaaaaaca agaataactt aaatcaaaaa gtttggttta attaacatag
    18001 atgtattaaa tagatgtatt gatgagtaaa tttgaattta agataaaata aagtaattaa
    18061 agttgattgt atagatgatg aagataagaa ctgtgaaaat tgtttagata aggagaaaga
    18121 gttatgccta aattagatag tataaagaaa actttagtat tagggtcagg gccaataata
    18181 ataggtcaag ctgcagagtt tgactattca ggaacacagg cctgccaagc attaaaagaa
    18241 gagggaattg aagttgtatt agtaaatagt aacccagcta ctataatgac tgataaagaa
    18301 attgcagata aaatatatat agaaccatta acaatagaat ttatagaaaa aataatagaa
    18361 aaagaaaaac cagatagttt acttgcaggt atgggtggtc agacaggatt aaacttagct
    18421 gtagaattac atgatgctgg tatattagat aaatataatg taaaagttat aggaacatct
    18481 atagaatcta taaaaaaggg cgaagataga gatttattta gagaagtaat gaaagaaata
    18541 aatcaaccag taatagttag tgatatagtt acaaatttag aagcaggtct tgagtttgcc
    18601 aataagatag gatatccagt agttgtaaga ccagcatata cgctaggtgg aactggtgga
    18661 ggtatagctg atactgagga agaattaaga gaaatacttt cacatggact acagctaagt
    18721 cctgttggac aagttcttct tgaaaagagt ataaaaggtt ggaaagaaat agaatacgaa
    18781 gtaatgaggg atggaaatgg aaactgtata actgtatgta atatggaaaa tgtagaccca
    18841 gttggagttc atacgggaga cagtatagtt gttgctccaa gtcaaactct aagtgatgaa
    18901 gagtatcaac tacttagaaa ggcatcaata gacataataa atgcaataga ggttcaaggt
    18961 ggatgtaacg ttcaaatagc tttaaaccca catagtttag aatatgcgat aatagaaata
    19021 aatccaagag ttagtaggtc atcagcccta gcatcaaaag ctacaggata cccaatagca
    19081 aaagtagcag ctaagatagc tttaggttat actttggatg agatagaaaa tgcagtaact
    19141 aaaaaaactt atgcttgttt tgagccaaca ttagattatg tggtagtaaa aataccaaag
    19201 tggccatttg ataaatttag acatgccaat agaaaattag gaactaagat gatggcaact
    19261 ggtgaaatca tgagtatagg aagtaacttt gaggctgcta ttcttaaagg tataagatca
    19321 cttgaaacag gaaaatattc attggttcat gctccatcag aaggtagaac attagaagaa
    19381 ttaaaggcta gagtagtagt acctgatgat gagagactat ttgacttagc tgaaatgata
    19441 agaagaggct ataaagtaga aatgatatca gaaataactg gtgttgataa gtggtttata
    19501 aataaattta aatggatagt agaacaagaa gaaaagttaa aagttctaaa aatagaagac
    19561 ttagataaag aatatttaca tgaattaaag aaaaagggat tttctgataa aggtatatct
    19621 gacttaatga agataagccc agaaaaatta tatgaattga gaagtttata taatatacaa
    19681 ccagtttata aaatggttga tacatgtgga ggagaatttg aagctctatc accttattac
    19741 tattcaactt atgaacaata tgatgaggta gtagttagtg ataagagaaa agttgtagta
    19801 ttgggttctg gtccaataag aataggtcaa ggaatagaat ttgactattg ttcagttcac
    19861 tgtgtaaaat ctttaagaaa aatgggaata gaaactataa ttgtaaacaa taaccctgaa
    19921 actgtaagta cggattttga tacatctgat aagttgtatt ttgaaccatt aacagaagaa
    19981 gaagttttaa atataataga aaaagaaaaa ccagaaggtg taatactaca gtttggtgga
    20041 caaacagcta taaaattggc taagttttta catgaaaaaa atatacctat actgggaaca
    20101 gactttagag atatagatgc agcagaagat agagaaaaat ttgatgattt actagagaga
    20161 ctagatataa atagaccaaa aggaaaaggt gtatggacaa ttaatgaagg tgttgaaatt
    20221 gctaaggagt taggttatcc agtattagtt agaccatctt atgtacttgg tggtcaaggt
    20281 atggaaataa cttataacga agaaaaacta attcagtatt tggatgatgc atttgataga
    20341 gaccataaaa atccagtact tatagataaa tatctaactg gtagagaaat agaagtagat
    20401 gctatatgtg ataaagaaga tatattgata cctggtataa tggagcattt agaaagagct
    20461 ggagttcact ctggagatag tacaacaatg tatccaagtc aaaatatatc tgatgaaata
    20521 aaagaaaaaa tagtagaata cactaaaaaa atagctttag accttaatgt gcttggtatg
    20581 gttaatatac aatttataga atttcaaaat gaattatata taattgaggt taaccctaga
    20641 gctagtagaa cagttccata tataagtaaa gtaagtggag taccaatagt tgacttggct
    20701 ac
//
LOCUS       DAEORM030000062        20622 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.062, whole genome shotgun sequence.
ACCESSION   DAEORM030000062 DAEORM030000000
VERSION     DAEORM030000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 20622)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20622)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 20622)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20622
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.062"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            200..1132
                     /locus_tag="KRH23_003083"
     CDS             200..1132
                     /locus_tag="KRH23_003083"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006441199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Rossmann-like and DUF2520 domain-containing
                     protein"
                     /protein_id="HHS5226360.1"
                     /translation="MGFIGSGKVGTSLANYFLSKGYCVSGFYGRNQLSLLESTNLTKT
                     KIYSNLKDIIYENDILFITTSDDSIEIIDKKLSKFNLKHKYICHTSGSLKSSILFCSK
                     KAGALIYSIHPIFAFSNKNTNIKKMKDICFSIEGDNEQDDLVIQNFIDDLGNQFFIRD
                     KDTSSTYHLANVLVSNLVLSLLDIGVSYFIKLGLSEEESLKAISPLVKKNIENILDNG
                     FTKALTGPVSRGDITPIRKHLSVLDKKDEDIYKILSLNLLKIIALGNDNSLKGIKNIT
                     IENAIENLISKSEKYKEIYKLLGGKNDEKYHTDF"
     gene            1107..1934
                     /gene="panB"
                     /locus_tag="KRH23_003084"
     CDS             1107..1934
                     /gene="panB"
                     /locus_tag="KRH23_003084"
                     /EC_number="2.1.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003864 - 3-methyl-2-oxobutanoate
                     hydroxymethyltransferase activity [Evidence IEA];
                     GO_process: GO:0015940 - pantothenate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate
                     hydroxymethyltransferase"
                     /protein_id="HHS5226361.1"
                     /translation="MKNTIQTFKNAKYEGKKLSMLTAYDYSIAKIMDECDINGILIGD
                     SLGMVIKGEENTLSVTIDEIIYHTKAVKNGVKNALIVSDMPFLSYHVSIEDAVKNAGR
                     LIKEGGAHAVKLEGGSNVIKQIESIVNAQIPVMGHLGLTPQSVNSFGGFKVQGNTSET
                     ARQLIEDAKLIEKAGAFSIVLEGVPTKIAEMVTNSISIPTIGIGAGINCDGQILVYQD
                     MLGMFGDFVPKFVKQYANIGDIMKDSIKNYILEVNTGAFPQEKHSFSINESELEKLY"
     gene            1953..2801
                     /gene="panC"
                     /locus_tag="KRH23_003085"
     CDS             1953..2801
                     /gene="panC"
                     /locus_tag="KRH23_003085"
                     /EC_number="6.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004592 - pantoate-beta-alanine ligase
                     activity [Evidence IEA];
                     GO_process: GO:0015940 - pantothenate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pantoate--beta-alanine ligase"
                     /protein_id="HHS5226362.1"
                     /translation="MLVKEIKLLRNIIKDWRKHGYSIGLVTTMGFLHEGHQSLIKKAV
                     KENDKVVVSVFVNPTQFGPNEDFNSYPRDIDKDFKYCMDSGATVVFNPSPEEMYLKGN
                     CTTINVSGLTDFLCGAKRPVHFGGVCLVVSKFLNIVTPDKAYFGEKDAQQLAVIKRMV
                     KDLNIDTEIIGCPIIRENDGLAKSSRNTYLSEEERKSALILNKSLSLAKEELVKGNLN
                     PENIKELITAKINSEHLAKIDYVEIVDSETLQPVKQIEHSILVAIAVFIGKTRLIDNF
                     TFELNI"
     gene            3212..3394
                     /locus_tag="KRH23_003086"
     CDS             3212..3394
                     /locus_tag="KRH23_003086"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226363.1"
                     /translation="MFKDKIDECVHIMTAYIASLKEYYSFIETQIGDFIKKYGEDVVE
                     LCLHRVMILLCECGLA"
     gene            4226..5140
                     /locus_tag="KRH23_003087"
     CDS             4226..5140
                     /locus_tag="KRH23_003087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2935 domain-containing protein"
                     /protein_id="HHS5226364.1"
                     /translation="MIDNQKYVILSLELHLFFSRIMKEHALFLEAGFTNKNYNLAMEA
                     DHYKKQFEDLLSYTVSASNGIIRPDILYSEELVTTLTSVAEQKTEEFTGIEINKNITT
                     RELNLQSGVNPQVGQDLVNYVAQLNSDAIRLLDGLINFKERVLDGVLSCTIFTSNYPL
                     LLEHIIHEANLYRSYVVDLENKIDIESKNAKEIELFWDHIMMEHALFMRGLLDPSEGE
                     LINTSNDFAIKFNELIEKTNEMTDSNIKNITEETLNETVEFKDFKEAGASGIEQCKIK
                     SIILPLLADHVLREANHYIRILESYKNM"
     gene            5530..6177
                     /locus_tag="KRH23_003088"
     CDS             5530..6177
                     /locus_tag="KRH23_003088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate utilization protein"
                     /protein_id="HHS5226365.1"
                     /translation="MIRQTPLEKRYDKLGPHIVTALKKRYFDAYYCKTRNEALQQILD
                     LIPQNHVVSWGGSETLKEMGVQTAVREKGFKVIDRDLAKTPEERTEIMRQALLCDTFL
                     MSSNAISEDGQLFNIDGNGNRVAAMIFGPKNVIVVAGMNKIVKNIDDAIQRTRTIASP
                     AVVQRFQDVNTPCYINGSCIDCTSPESICAYMVTTRISRPAKKIKVILVGENLGL"
     gene            complement(6344..6913)
                     /locus_tag="KRH23_003089"
     CDS             complement(6344..6913)
                     /locus_tag="KRH23_003089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226366.1"
                     /translation="MKKFIICIIMFAISVLVLAGCTNDNKIKNEVDSMFNSIKTQDAD
                     TVDKYFPKSGLGNLIYEDKEGFKMYSKNMTWEISDIKNNKDKVTVDLKINNTDMVSIL
                     KKNPPKLGEMMPNPTMKDIDSAKKKEFNITLELVKSGDNYVCKVNQESAMKLLNVITG
                     GGIDYLADYNKEYYKQLDEEQKNYENKNS"
     gene            complement(6918..7817)
                     /locus_tag="KRH23_003090"
     CDS             complement(6918..7817)
                     /locus_tag="KRH23_003090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HHS5226367.1"
                     /translation="MKLLSKVNNNIRLITQVAFTALTNGYVNGFLEGTIYGGESKKLC
                     VPGLNCYSCPGALGACPIGSLQAVLSSREYKFSFYVVGFLMAFGAFFGRFVCGWLCPF
                     GLVQDLLHKVPFPVKIKKVYGDKYLKYLKYIVLIMFVIILPVAIVNVAGGGNPWFCKW
                     ICPSGTLLGGIPLILGNENLRESIGFLFSWKLSILLLILLMSIITYRPFCKYICPLGA
                     IYGFFNSISIYRFKIDKDKCTNCTACQTKCKLDIPIYKDVNSPDCIRCGECIKVCPQN
                     AITTTFSKDKKENNICAKKYRGI"
     gene            complement(7828..7977)
                     /locus_tag="KRH23_003091"
     CDS             complement(7828..7977)
                     /locus_tag="KRH23_003091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CD1871A family CXXC motif-containing protein"
                     /protein_id="HHS5226368.1"
                     /translation="MSNFIKDNKKGISIIAISIIFIALGTYRGETNTVLTKAIMICLE
                     CIGIG"
     gene            complement(7970..8554)
                     /locus_tag="KRH23_003092"
     CDS             complement(7970..8554)
                     /locus_tag="KRH23_003092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
                     /protein_id="HHS5226369.1"
                     /translation="MKRFFIVVLGCICVLGMISGCSKKESKPVEKNKNNSEWFSNLDT
                     EDVDGNKVTKEIFSNKELTLINVWTTWCGPCVGEMPELEALSKEYESNNSNVAIKGLV
                     VEVDKTDMRTGLSNEEKNLVKDIMKKSDATYQQLTVSEELKKTDFKRVMEFPTTYFVD
                     KKGNFVGEKVVGANSKEDWKKIIDERLKMVKANE"
     gene            8943..10268
                     /gene="cdeA"
                     /locus_tag="KRH23_003093"
     CDS             8943..10268
                     /gene="cdeA"
                     /locus_tag="KRH23_003093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MATE transporter CdeA"
                     /protein_id="HHS5226370.1"
                     /translation="MENLFTRKFTTFEFLKFVSPAIISMIFISLYTIIDGIFVSTLVG
                     SDALASINIVLPIINLVCGFGIMMATGGGAIVSIRMGENRQDEANSTFSFIVLFSLIV
                     GILFTVISYFFIKEISILLGATDKLLPYCITYGKVMILCTPFYILKFIFEYFARTDGN
                     SKFSLFLSVIGGVTNIILDYVFIKYFGMGLLGAAVATAIGIILTCVLGIIYFLSNKST
                     LKLRKPKTDFRLIRDTMINGSSEMVTELSTGITTFLFNVVALKLAGENGLAALTIVLY
                     AHFLMTSVYLGFAAGVSPLISYNFGAENSDKLKETFKHSLKFIFISSLLVFIIALVFA
                     PFIVRVFVNPDNTVFKLALQGLKIFAFAFLFVGINIFASGFFTAFHNGKISAIISFSR
                     AFVFIIIGIIILPPMLNMTGLWLTVPFAEVITIFISILFIKKYKGRYKY"
     gene            complement(10363..11157)
                     /locus_tag="KRH23_003094"
     CDS             complement(10363..11157)
                     /locus_tag="KRH23_003094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHS5226371.1"
                     /translation="MNELKPYIKFFNKNTKLYIIIFMIVGIVMNILPVFILKIFGEAS
                     KTNLSTIVNPILTYITILLFVYGVNIANKDFSGALSIRADRKSCIKAIVIDLIILSFV
                     ISILGIVLIFLSKLFIEIITGYSIELSVLLKRDMIWTSISALIDPSTSSMPLTYLNYF
                     VQICINEICIGFIGVLLGAFTYRVRKVTSITILIGLPILMVIYIVNFATKNMHKMLLY
                     LEKIIYSFQNPFILFGTKVGIIVICIIFIILLLRKAPIKEYANDLL"
     gene            complement(11158..12033)
                     /locus_tag="KRH23_003095"
     CDS             complement(11158..12033)
                     /locus_tag="KRH23_003095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HHS5226372.1"
                     /translation="MSSSIKIENLSHSFKKQNIFNNMSLNFEKNKIYGLLGKNGAGKT
                     TLLNIMVNQLIQNEGEIEILGKNPKEDIKVLEEVCIVREKEFYSPDFKVGQIFEFSSS
                     FYKSYDKGLEEELCKYFDLNTKKKYKQLSRGMKTILSNIIGICSNSAITIFDEPTIGL
                     DAVNRQEFYNVILDSYIKNPRTIIISTHLIDEIDDLLEHVIILNEGKIIIDEEIDVIK
                     QRAHYITGNKEELEKLECIKNIKPKKVFGNAVAYFYYGDFSENDEKILKNSNIDVGYI
                     GLQDMFVNMTKKEEL"
     gene            complement(12037..12405)
                     /locus_tag="KRH23_003096"
     CDS             complement(12037..12405)
                     /locus_tag="KRH23_003096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HHS5226373.1"
                     /translation="MKLVLNNEEPIFIQIARAIEDEILSNGIKEEEQVPSTTELSKLY
                     KINPATVLKGINILVDKNILYKKRGIGMFVSDGAKTIIKEARKENFKHNFVKNLLQEA
                     NKLEINREELVDIIINFKED"
     gene            complement(12588..13247)
                     /gene="deoC"
                     /locus_tag="KRH23_003097"
     CDS             complement(12588..13247)
                     /gene="deoC"
                     /locus_tag="KRH23_003097"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004139 - deoxyribose-phosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0009264 - deoxyribonucleotide catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HHS5226374.1"
                     /translation="MKHILKTVDHTILKATTTWEDIKILCDEAVDMSVASVCIPPSYV
                     KRASEYLKGKIKICTVIGFPLGYQTTATKVFEAKDAIENGADEVDMVVNISDIKNKDY
                     DNIGKEIKEIKKAIGDKVLKVIIETCYLDEDEKIKMCEIVTMSGSDFIKTSTGMGTGG
                     ATLEDIKLMKEHVGKNVKIKAAGGVKSISDAEKFIEAGAERLGTSSICKILKNEDTTD
                     Y"
     gene            complement(13283..14827)
                     /gene="murJ"
                     /locus_tag="KRH23_003098"
     CDS             complement(13283..14827)
                     /gene="murJ"
                     /locus_tag="KRH23_003098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0034204 - lipid translocation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="murein biosynthesis integral membrane protein
                     MurJ"
                     /protein_id="HHS5226375.1"
                     /translation="MSKVAKATFYLMIVTIISKILGMGRELVLSSIYGTGLYTESYLT
                     AMNIPNIIFAAIGTAIVTTFIPMYQDISSKQGEKQALKFLNNVLNIIVGICIVVAILG
                     VIFSKQLVSIFAIGFEGERFLLTVKFTKILIIGIIFIGITSVMSAFLQIKENFIVVGF
                     GSIPYNIVIIISIMLSTVFGPYILPIGAVVAMVVQLLFYMFFVKKTNYKYLHYLNFKD
                     DSLIKLLALLSPVFIGVAVNQVNSLVDTTLASTLVKGSIPALTYADRLNGFVTGTFTA
                     SIVSVMYPMLSKLSAENNQKKFTSSVKSSINMIIISMIPISVASIFFATPVVRIIFER
                     GAFDARATQMTATALIFYAVGMTAFGLRDILGKVFYSLQDTKTPMVNGIISVGVNIVL
                     DLVLIKPMAHGGLALATSSSSIACILLLFLNLKRKVGYFGQDKIIKATLKSVVASLIM
                     GVLSYFTYKFIFGILGVGTFNEFVSLAISVIVGGGIYTLLMTIFKVEEVDMILNIAKR
                     KLHLKK"
     gene            complement(15301..16185)
                     /locus_tag="KRH23_003099"
     CDS             complement(15301..16185)
                     /locus_tag="KRH23_003099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HHS5226376.1"
                     /translation="MDTKKENNYENYICVGSSNVSNAMKMYLKEIEEYKMLSAGEEVE
                     LAKEIINSSSVAKEKFINSNYRLVVSIAKRYKRDSIDMLDLIQAGNIGLIKAVEKYDY
                     KKGYKFSTYATWWIKQSITRYIDDCENTIRIPIHLHQRINFVKKKKQELLNVLLREPT
                     IDEIADACGLEVDKVLELLRRDKNVVSLDTPLKEDEDSSLVEFIPSDADFKDVVIHEV
                     EQHNLKEKIEELLTGLGEQEQQVLRMRFGIDDDDPKTLEQIGKVFGVTRERIRQIEAK
                     AIRKLRHPSKLKQLKHFY"
     gene            complement(16476..16952)
                     /locus_tag="KRH23_003100"
     CDS             complement(16476..16952)
                     /locus_tag="KRH23_003100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction enzyme HsdR N-terminal
                     domain-containing protein"
                     /protein_id="HHS5226377.1"
                     /translation="MSKELVKDRVIKYLIEDLLVPQDMIDTNVELAEFEEGAEGILDI
                     VVNVKDEEDYYAPVMIVQCLDEDVELEGEVLQKQIEFLEEVDNITMSGRLVLTNGDAM
                     MYADWRGEEYDTEAALPTYDIMVKEFHEMEQQVKDLEEHHHHDENCGCGCNHHHEN"
     gene            17219..18394
                     /locus_tag="KRH23_003101"
     CDS             17219..18394
                     /locus_tag="KRH23_003101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HHS5226378.1"
                     /translation="MKFKKQISSIVVSTMLVLGSMNLSYADGTNVVTLGANLSESQKQ
                     QMLNYFGVKKDQVLVLDVTNAEERQYLQGVATEGQLGKVTISCSYVEPTKKGNGINVK
                     TANLTWVTSSMIASTLTTAGLEDANVIAAAPYPVSGTGALTGIMKAFEDASGKKLDET
                     KKEIASEELVVTGDLGDDIGQEKATGVMNDIKTEIVKNGTKDTNQIANTINNVVNNYN
                     ITITPEQKEQIKGVMKKIADQNYDYNSMKNTLDNVSDNVNEQLKKLGESVKGSGILDT
                     IGGWFSGIGDWFSGLFSGGDKKDLGILNNTNDESLGSDAVINSTEGVQINPQNNTNSN
                     NDSDTNSSKNDTSSNNENNDSSQTNENNTTNNSENQSNNNDSVGFFEKIKNWLSGLF"
     gene            complement(18475..19278)
                     /gene="proC"
                     /locus_tag="KRH23_003102"
     CDS             complement(18475..19278)
                     /gene="proC"
                     /locus_tag="KRH23_003102"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004735 - pyrroline-5-carboxylate
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HHS5226379.1"
                     /translation="MKKIGFIGAGNMASAMIGGIVNSKLVEPNMVIASAYSQGTLDRI
                     DANFGINTTKDSKEVTRTSDIVIVAVKPDIYDDILEEIKDFIDDNKIIVTIAAGKSIK
                     DIESIIGEDKKIVRTMPNTPALVNEAMSSLSINKNINKEDLEAVTEVFNSFGNTEVVP
                     EYLIEAVIGASGSAPAYVFLFIEAIADAAVIAGMPRPQAYKFASQAVMGSAKMVLETG
                     KHPGELKDMVCSPGGTTIEAVKVLEEEGFRASVIKAICACIEKSKKMSE"
     gene            complement(19318..19908)
                     /locus_tag="KRH23_003103"
     CDS             complement(19318..19908)
                     /locus_tag="KRH23_003103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHS5226380.1"
                     /translation="MVLNKDIGAKIKQLRTQKQMTLKDMSEKTNLSIGFLSQLERGLT
                     SVATDSLGKIASVLDVELTYFFMKPKEHKRAVLRSYEKEVFDVENSTFIHYHLSSSLK
                     EKTMLPRLIEILPSKSSEEICCYVHEGEEFVYVLEGTLTVFLGDEQIEMYPGDTIHYN
                     SEKNNHNWVNYTNKVVKILVVSIPNPFEKSDAVKEA"
BASE COUNT         7313 a         3115 c         2421 g         7773 t
ORIGIN      
        1 actgatattt tattatataa attttataga attaattgtc aattttttat gaaaatggta
       61 agatatttat ggatggtatc ttgttataag aactatactt taaatgtttt taattatttt
      121 gtcttatgta actcatatcc tcaggaatga gattagaaat taagatgttg tatcacaaag
      181 tggaggtgat actattaaaa taggctttat tggttctgga aaagttggaa catctttggc
      241 aaattatttt ttatcaaaag gttattgtgt ttcaggcttt tatggaagga atcaattatc
      301 tttattagaa tcaacaaatt taacaaaaac aaagatttac agcaatttga aagatataat
      361 ttatgaaaac gatatattat ttattacaac atcagatgat tctattgaaa ttatagacaa
      421 aaaactttcc aaatttaatt taaaacataa atacatttgc cacacaagtg gctctttaaa
      481 atctagtata ttgttctgtt caaaaaaagc aggtgcatta atttattcta tccatcctat
      541 atttgcattt tccaataaaa ataccaacat aaaaaaaatg aaagacattt gtttttccat
      601 agaaggtgat aatgaacaag atgatttagt tattcaaaat ttcatagatg atttgggaaa
      661 ccaatttttt ataagagata aggatacttc atccacttat catttagcta atgttttagt
      721 ttcaaattta gtattatctt tactagatat aggagtaagt tactttatta aattaggttt
      781 atctgaagag gaatctttaa aagctatcag tcctttagta aaaaaaaata tagaaaatat
      841 acttgataat ggctttacta aagctcttac tggtcctgtt tctcgtggag atataacacc
      901 aataaggaaa catctatctg tattggataa aaaagatgag gatatttaca aaatactatc
      961 cttaaaccta ctaaaaataa ttgccttagg aaatgacaat tcattaaaag gtataaaaaa
     1021 tattactata gaaaatgcaa tcgaaaattt aataagtaaa tctgaaaaat acaaagaaat
     1081 ttacaaactt ttaggaggaa aaaacgatga aaaataccat acagactttt aagaatgcta
     1141 aatatgaagg aaaaaaacta tctatgctta ctgcttatga ctactcaatt gcaaaaataa
     1201 tggatgagtg tgatataaat ggtattttaa taggagattc attaggaatg gttataaaag
     1261 gtgaagaaaa cactctatct gttaccatag acgaaattat atatcataca aaagctgtaa
     1321 aaaatggtgt aaaaaatgcc ttaatcgtaa gtgatatgcc ttttctatct taccatgttt
     1381 ctatagaaga tgcagttaaa aacgctggta gacttataaa agaaggagga gctcatgctg
     1441 taaagttaga aggtggctca aacgttataa agcaaataga aagcattgta aatgctcaaa
     1501 tacctgtaat ggggcattta ggattaactc ctcaatcagt aaattcattt ggtgggttta
     1561 aggttcaagg aaataccagt gaaacagcaa gacaacttat tgaagatgct aaattaatag
     1621 aaaaagcagg tgcattctct attgtccttg aaggagtgcc tacgaaaata gctgagatgg
     1681 taactaattc tatttcaatt cctacaatag gtataggggc aggaattaac tgtgatggac
     1741 aaattttagt ttatcaagat atgttgggaa tgtttggaga ttttgttcct aagtttgtaa
     1801 agcagtatgc aaatatagga gatataatga aagattcaat taaaaattac atcctagaag
     1861 ttaatacagg tgcatttcca caagaaaaac acagcttttc aataaatgaa tctgagttag
     1921 aaaaattata ctaatattaa ggatggtaca aaatgcttgt aaaagaaatt aaattactaa
     1981 gaaatataat caaagattgg agaaaacatg gctattctat agggcttgtt acaacaatgg
     2041 gatttttaca tgaaggacac caaagtctta taaaaaaagc tgtaaaagaa aatgataaag
     2101 tagtagtgag tgtatttgta aatccaactc aatttggacc aaatgaagat tttaatagct
     2161 atccaagaga tatagataaa gattttaaat attgtatgga tagtggagca acagtagtct
     2221 ttaacccatc accagaagaa atgtatttaa aaggtaattg tactaccatt aatgtttctg
     2281 gacttacaga ttttctttgt ggagctaaaa gacctgttca ttttggaggt gtctgcctag
     2341 ttgtttcaaa gtttctaaat atagtaacac ctgataaagc ttattttgga gagaaggatg
     2401 cccaacaatt agctgtaatt aaaagaatgg tcaaggattt aaacatagat acagaaataa
     2461 taggctgtcc tataattcgt gaaaatgatg gattagcaaa aagttcgaga aatacatatc
     2521 tctctgagga agaacgaaaa tctgctctaa tattaaataa gagcttaagt ttagcaaaag
     2581 aagaattagt aaaaggcaat ctaaatccag agaatataaa agaattaata acagctaaaa
     2641 taaattctga acacttagca aaaatagact atgttgaaat tgtagatagt gagacattac
     2701 aacctgttaa gcaaatagaa cattctatac ttgtggcaat tgctgtgttt ataggaaaaa
     2761 ccagactaat tgataatttt acatttgagt taaatatata gtctataatt ttatataata
     2821 tatctaaaaa ataatagaat acctaaaaag taataaatta cctaaaaaat aataaattgc
     2881 ttagaaaata atagattaca ataactaaaa ttttaaaatt aaattcctta aaagtatgat
     2941 taattataat tatataagta tattcttatt acacttatat taatttatat taaatatcta
     3001 ctaactcaaa tattcataat taaactttaa actggataaa ttttctttta agaatgaaag
     3061 tttatccagt tttgcgatta taataaccag ttttacatat ccacttgtaa aatatatcta
     3121 agcaatatat catactatat agatttatga gtgaaataat atctgctatt tactgaatat
     3181 ttttattttt cgttttttag ggggattagt tgtgtttaaa gataagattg atgaatgtgt
     3241 tcatataatg actgcatata ttgctagttt aaaagaatac tattcattca tagaaactca
     3301 aattggtgat tttattaaaa aatatggaga agatgttgta gagttatgtc tccatagagt
     3361 gatgattcta ctatgcgaat gtggtttggc ataaaattaa atttattaaa atgggtaaga
     3421 agaatcctat ataatattct tcttacccat tttaatatat caatttcata gcttatcgtt
     3481 taaaatattt tacatccatt actagacaac tttacattct ctttttaatt ctagtatatt
     3541 taaatcattt tagttgctcc ttatttattc ttattacttg ttttatttta taaataaaat
     3601 aattcttttt aataatgttt tttgttgata ttcctatcac acatccaatt atttatcatt
     3661 gtcttgaaat tgtttgcata cttaatttaa tccaattgaa acaccccagc atagaatccc
     3721 ctgtaaaata gaagttggat taaatcctaa catctataca gaaaatacta ctccaagcac
     3781 aagcaatata atggaatata tttatcactt aattttttat actttttaaa tcccatacct
     3841 aaaacattaa gtgcagctat tagaattaat aattgttgtg gtataaaatt atgcttgctt
     3901 catatttatt cattttttgc tataaaagtt cttgttttac aaaaaacatt tgttttgtat
     3961 caaaataata cttataaatt acataattct cataaaaatt tctagtatta cttgtactct
     4021 taataaataa tagccaacaa gtatcttaaa tcattatatc tatatctaat aagaaacaca
     4081 gtaagataat tttttcgccc ataacttaat aaaaactgtt gatattagta gcaattgaat
     4141 ttagttaatt tatttataat atacataaat ttaaatatta cgaataaagt attataaata
     4201 ggatactttc taaagggagg aaattatgat agataatcaa aaatatgtta ttttatcact
     4261 agaattacat ttattttttt caagaattat gaaagagcat gctctttttt tagaagcagg
     4321 attcacaaat aaaaattata atcttgctat ggaagctgac cactataaaa agcaatttga
     4381 agatttatta tcatacactg ttagtgctag taatggtata attagacctg atatattata
     4441 ttcagaagag cttgtaacta ctctcacatc agttgcagaa caaaaaacag aagagtttac
     4501 agggatagaa ataaacaaaa acatcactac aagagaatta aatctacaaa gtggtgtaaa
     4561 cccacaagtt ggtcaagact tagtgaacta tgtagctcaa cttaactctg atgcaataag
     4621 attacttgat gggcttatta attttaaaga aagagtctta gatggtgtac tatcatgtac
     4681 tatatttaca tcaaactacc ctctactcct tgaacatata atacatgaag caaatttata
     4741 tcgttcttat gtagttgacc ttgaaaataa aatagatatt gagtcaaaaa acgctaaaga
     4801 aatagaatta ttctgggacc atattatgat ggaacatgct ctgtttatga gaggattact
     4861 agacccatca gaaggtgaac taataaatac ttcaaatgat tttgctataa aatttaatga
     4921 attaattgaa aaaacaaacg aaatgactga ttctaatatc aagaacatta cagaagaaac
     4981 tctaaatgaa actgttgagt ttaaagattt taaagaagca ggagcatcag gaatagaaca
     5041 gtgtaagata aaatctataa tattaccact tttagcagac catgttttaa gagaggcaaa
     5101 tcattatatt agaatattgg agagttataa aaacatgtaa ttaaaaatta cttttaaaat
     5161 aatctttgca tatttagata aaataaaggt acagttaact gtacctttat tttttataaa
     5221 cttataaaat ttaaacaagt tattcataaa ataaaataat aatcatctat aacccacaac
     5281 tttattttat attaaataaa aagtattagt gattatgttt tataagtatt tctttattca
     5341 gttatttatt aaaaactaat agtaaatctt atactaatcg catatttatg ttataactat
     5401 attgtaacta ttttcgtaat cttaggaaaa gattacttat aaaattaacc ttatacaata
     5461 atatatcgta taatcttaat tagcataata gttacaatat taaaatttaa atatgggagt
     5521 gattttagta tgataagaca aacaccatta gagaaacgat atgacaagct aggtcctcat
     5581 attgtaacag cactcaaaaa acgttatttt gatgcttatt actgtaaaac tagaaatgaa
     5641 gctttgcaac aaattttaga tttaattcct caaaatcatg tagtatcatg gggaggatct
     5701 gaaacactta aagaaatggg cgtacaaact gctgttagag agaaaggatt taaagttatt
     5761 gacagagatt tagcaaaaac tccagaagaa agaactgaaa ttatgcgtca agcacttcta
     5821 tgcgatactt ttttaatgag tagcaatgca attagtgaag atggacaact ctttaatatt
     5881 gatggaaatg gcaatcgtgt agctgcaatg atatttggtc caaaaaatgt tatagttgta
     5941 gctggtatga ataaaattgt aaaaaacatt gatgatgcaa tacaaagaac tagaacaatt
     6001 gcatctccag cagttgttca gcgttttcaa gatgtcaata caccatgcta tattaatgga
     6061 agttgtatag attgcacaag ccctgaaagc atttgtgcat acatggttac tacaagaatc
     6121 agtcgtccag caaaaaaaat aaaggtaata ttggtaggag aaaatcttgg tctataaaat
     6181 atacatacat gtaaatagct ctataaataa taaaatcata tgaaataact tatttctaaa
     6241 agtggtagaa taaaagcttc tacaagactt tcattctacc acttttatat tcttttaatt
     6301 tgtgtttcta tattattaat tgctccgatt ttcatatata ttactaacta tttttatttt
     6361 cataattttt ttgttcttca tcaagctgtt tataatattc tttattatag tcagctagat
     6421 aatctatacc acctcctgta atcacattta ataatttcat tgcagattct tgattaactt
     6481 tacaaacata attatcacca gatttaacaa gctctaatgt aatattaaat tcttttttct
     6541 ttgcagaatc aatatctttc atagttggat ttggcatcat ttctcctagt ttaggaggat
     6601 tcttttttaa aatagaaacc atatcagtat tgttaatttt taaatctaca gtcactttat
     6661 ccttattatt ctttatatct gaaatttccc aagtcatatt tttagaatac attttaaatc
     6721 cttctttatc ttcgtatata agattaccta accctgattt tgggaaatac ttatcaacag
     6781 tatctgcatc ttgtgttttt attgaattaa acatactatc cacttcattt tttatcttat
     6841 tatcattagt acaaccagct aacaccagta ctgatattgc aaacattata atacatataa
     6901 taaatttctt cattaaatta tatcccccta tacttttttg cacaaatatt attctctttt
     6961 ttatcttttg aaaaagttgt agtaattgca ttttgtggac aaacttttat acattcacca
     7021 cacctaatac agtctggact atttacatct ttatatattg gtatatcaag cttacatttt
     7081 gtttgacatg ctgtacaatt tgtacattta tctttatcaa ttttaaatct atatattgaa
     7141 atagaattaa aaaaaccata gattgctcct aaagggcata tatacttgca aaatggccta
     7201 taagtaatga ttgacatcaa taatatcaat agcaaaatac ttaacttcca gctaaataaa
     7261 aatcctattg attctcttaa attctcattt cctaaaataa gtggtattcc tcccaaaagt
     7321 gttcctgaag ggcaaatcca tttacaaaac caaggatttc caccccctgc tacatttaca
     7381 atagcaactg gcaaaataat tacaaacatt attaagacta tatactttag atattttaga
     7441 tatttatcac cataaacttt ttttatcttt actggaaagg gtactttatg tagtaaatct
     7501 tgtacaagtc caaagggaca aagccaacca caaacaaatc tgccaaaaaa agcaccaaat
     7561 gccattaaaa aaccaacaac ataaaatgag aatttatact ctctgcttga taaaactgct
     7621 tgtaatgaac ctattggaca tgctccaagt gcacctggac atgaataaca attcaatcca
     7681 ggtacacata attttttact ttctcctcca tatatagttc cttctaaaaa tccatttaca
     7741 tatccatttg ttaatgctgt aaatgcaact tgagtaataa gtcttatatt attatttact
     7801 ttagataata acttcattcc tcttctccta accaatacca atacactcaa gacaaatcat
     7861 aattgcttta gttaatactg tatttgtttc tccacgatat gtacctaatg caataaatat
     7921 aatactaatt gcaataatag aaatgccttt tttattatct ttaataaaat tactcattgg
     7981 cttttaccat ttttagtctt tcatctataa tttttttcca atcttcctta ctatttgcac
     8041 ctacaacctt ctcacccaca aagtttcctt tcttgtctac aaaataagtt gttggaaact
     8101 ccataactct tttaaaatca gtttttttaa gttcttcaga tacagtcaat tgttggtaag
     8161 ttgcatctga ctttttcata atgtctttaa ctaaattttt ctcttcattt gaaagaccag
     8221 ttctcatatc agttttatca acttctacaa ctaatccctt tatagctaca ttggaattat
     8281 tactctcata ttcttttgat aatgcttcaa gctctggcat ttcacccaca catggtccac
     8341 accaagtagt ccagacatta ataagagtaa gttctttatt tgaaaatatc tcttttgtta
     8401 ccttatttcc atcaacatcc tccgtatcta aattactaaa ccattcacta ttattcttgt
     8461 ttttttctac tggcttagat tcttttttgc tacatccaga aatcatacct aaaacacaaa
     8521 tacatcctaa aactactatg aaaaaccttt tcatatctca cactcctaga atttatatag
     8581 tatataaaat cgctgcttga aataaaaata acttatcttc tatattaaag taattatatt
     8641 taataaataa gagctaattt aaaaaaagat atacagttaa aatctatttc ttttcataca
     8701 aaatcttata tatatataat agcttgtaaa tcttaagatt atatacatat atttctaaag
     8761 attttcttaa gaaacagtta gattttacta atataagttt attaattagc attatactaa
     8821 tttatcttaa tatgattttt tgttgatttt aagctgttta tcgtataaat aaaatttttc
     8881 ttgactatat agttactata tagcttatta tatatagaga gtaataaaag gaggtaaaat
     8941 ttatggaaaa tttatttaca agaaaattca ctacttttga atttctaaaa tttgtttctc
     9001 ctgcaattat atccatgata tttatatctt tgtacacaat aatagatggc atctttgtat
     9061 cgacattagt tggttctgat gctcttgcta gtataaatat tgtactacct ataattaacc
     9121 ttgtttgtgg atttggaata atgatggcaa ctggtggagg tgctatcgtt tctatacgta
     9181 tgggtgaaaa tagacaggat gaagccaact ctacattttc ttttatagtt ttgttttcat
     9241 tgattgttgg gattttattc acagtaatct catatttctt tatcaaagaa atatctattt
     9301 tgcttggtgc aacagataag ttattaccat attgtataac ttatggtaaa gttatgattt
     9361 tatgtacacc attttatatt ttaaaattta tatttgagta ctttgcaaga actgatggaa
     9421 attctaaatt tagtttattt ctatcagtca ttggtggtgt aacaaatata atattggatt
     9481 atgtatttat taaatatttt ggaatgggtc ttttaggagc tgcagttgca actgctatag
     9541 gtattatttt aacttgtgtt ttaggtatta tttacttctt atctaataaa tctacactaa
     9601 aattaagaaa accaaaaacc gattttagac ttataagaga tactatgata aacggttctt
     9661 ctgaaatggt tacagaatta tctacaggaa ttacaacatt cttatttaat gtagtagctt
     9721 taaaattagc aggagaaaat ggacttgctg ctcttactat agtattgtat gctcattttt
     9781 taatgacatc agtctatcta ggattcgctg ctggagtgtc tccattaata agctataatt
     9841 ttggtgctga aaacagtgat aaattaaaag aaacatttaa acattctcta aaatttatat
     9901 ttatttcttc tcttttagtg tttattattg ctttagtatt tgcaccattt attgttaggg
     9961 tctttgtaaa tccagataac acagtattta aactagcctt acaaggatta aaaatatttg
    10021 catttgcttt tttgtttgtt ggtataaata tatttgcatc aggatttttt acagcatttc
    10081 acaatggaaa aatttcagct attatatctt ttagtcgtgc ctttgttttt ataatcatag
    10141 gaatcataat tcttcctcct atgttaaaca tgactggatt atggcttaca gttccatttg
    10201 ctgaggttat aaccatattt atatctattc tatttataaa aaaatataaa ggtagatata
    10261 agtattaaaa attaatactt aaaatcaaca tttattaaaa ctaataaacc tgctttaaaa
    10321 tacaaattta caaatttgat ttttaagcag gttttatttt agttataata agtcatttgc
    10381 atactcttta attggtgctt ttctaagtaa taaaattata aatattatgc aaataactat
    10441 aattcctacc tttgttccaa ataaaataaa aggattctga aatgaataaa taattttttc
    10501 taaatacaat agcattttat gcatattttt agttgcaaaa ttaactatat aaattaccat
    10561 taatatcggt aatcctatca atatagtaat actagtaact tttctaactc tatatgtaaa
    10621 agctccaagt aacactccta taaaacctat acatatttca tttatacata tttgtacaaa
    10681 ataatttaaa taagttagtg gcatacttga tgttgaagga tctatcagtg ctgatataga
    10741 tgtccaaatc atatctctct ttagtaaaac tgatagttct atactataac ctgttataat
    10801 ttctataaat aacttcgata aaaaaatcaa aactatacct aaaatagaaa tcacaaagct
    10861 taaaataatt aaatctatga caatagcttt tatacaactt tttctatctg ctcttatact
    10921 taaagctcct gaaaagtctt tatttgctat atttactcca tacacaaata gcagtatagt
    10981 tatatatgtt aaaataggat tcacaatcgt ggataaatta gttttagatg cttctccaaa
    11041 aatcttgagg ataaacactg gcaaaatatt cataacaatt cccacaatca taaatataat
    11101 tatatacaat ttagtatttt tattaaaaaa ttttatatat ggctttaatt cattcaatta
    11161 caattcctcc ttcttagtca tgttaacaaa catatcttgt agccctatgt atcctacatc
    11221 aatatttgaa tttttaagta ttttttcatc attttcacta aaatcaccat agtaaaaata
    11281 agcgactgca tttccaaata cctttttagg ttttatattt tttatacatt ctaatttttc
    11341 taactcttct ttatttccag taatataatg agctctttgt tttatgacat caatttcttc
    11401 atctataata atttttccct catttaatat tattacatgc tccagtaaat catctatttc
    11461 atcaatcaaa tgagttgata ttattattgt ccttggattt tttatataac tatctaaaat
    11521 tacgttataa aactcttgtc tatttactgc atccagacca attgttggct catcaaatat
    11581 ggtgatagct gaattagaac aaatacctat tatatttgaa agtatagttt tcatacctct
    11641 tgacagttgt ttatactttt ttttagtatt taaatcaaaa tatttgcata attcttcttc
    11701 taagccttta tcataacttt tataaaaact agaagaaaat tcaaatatct gacctacttt
    11761 aaaatctgga ctataaaatt ctttttccct gacaatacaa acttcttcca aaacttttat
    11821 atcttctttt gggttctttc ctaatatttc tatctcacct tcattttgaa ttaactgatt
    11881 taccattata tttaataatg ttgtttttcc agctccattc ttacctaata aaccatatat
    11941 cttatttttt tcaaagttta gagacatatt attaaaaata ttttgcttct taaaactgtg
    12001 agataaattt tctatcttaa tagaactact catatattaa tcctccttga aattaattat
    12061 aatatcaacc aattcttctc tatttatttc taatttgtta gcttcttgaa gtaggttttt
    12121 tacaaaatta tgtttaaaat tttcttttct agcttctttt ataatagttt ttgcaccatc
    12181 tgatacaaac atccctatcc ccctcttctt atataaaata tttttatcaa ccaatatatt
    12241 tatacctttt aatactgtag ctggattaat tttataaagc tttgaaagct ctgttgttga
    12301 tggaacctgt tcttcttctt ttattccatt tgatagtatc tcatcttcaa ttgctcgtgc
    12361 tatctgaata aatataggtt cttcattatt taatactaat ttcataggtt cctcctttct
    12421 ccatcagtta gttactcaac taattaacta tataacttat aatatcttga aaaatatttt
    12481 ttgtcaatac taaataaaaa acagagggaa aattccctct gttttttgtt ctttatattt
    12541 ataattaaat tttaattttt gtaatcctat cccataagtt aaaaacttta ataatctgtt
    12601 gtatcttcat tttttaatat tttacatatt gagctagttc ctaacctttc tgctcctgcc
    12661 tctataaatt tttctgcatc agaaattgat ttaactcccc ctgcagcttt tatttttaca
    12721 ttttttccaa catgctcttt cataagcttt atatcttcta aagtagctcc acctgttccc
    12781 attccagtag atgtttttat aaaatctgaa cctgacattg ttactatttc acacattttt
    12841 attttttcat cttcatctaa ataacatgtc tctataatga cttttaatac tttatctcct
    12901 atagcttttt ttatttcttt tatttctttt cctatattat cataatcttt attttttata
    12961 tctgaaatgt ttacaaccat atcaacttca tctgctccat tttcaatagc atcttttgct
    13021 tcaaatactt ttgtagcagt agtttgatat cccaaaggga accctatcac tgtacatatc
    13081 tttattttac cttttagata ttctgatgct cttttcacat atgatggtgg tatgcaaact
    13141 gatgctacac tcatatctac agcttcatca cataaaattt taatatcttc ccatgtagtt
    13201 gtagctttta aaatagtatg gtctactgtt tttaatatat gtttcataaa atcctcctaa
    13261 atttataatt aatataatta gattactttt ttaaatgcaa ttttctcttt gcaatattca
    13321 gtatcatatc aacctcttca actttaaaaa tagtcattag tagtgtataa attccacctc
    13381 caactataac tgaaatagct agtgatacaa actcattaaa tgttcctact cccaaaattc
    13441 caaatataaa tttatacgta aagtatgata aaacacccat aattaaagat gcaactaccg
    13501 atttcaaagt tgcttttatt attttatctt gtccaaaata tccaactttt ctctttaggt
    13561 tcaagaagag taacaatata catgcaattg atgatgaact agttgcaaga gcaagaccac
    13621 catgagccat tggttttatt aaaactaagt ctaatactat atttacccct acagatataa
    13681 tcccatttac cataggtgtt tttgtgtctt gtaatgaata aaaaaccttt cccaaaatat
    13741 ctcttaaacc aaatgcagtc ataccaactg cataaaaaat taaggcagtt gctgtcattt
    13801 gggttgccct cgcatcaaaa gcacctctct caaaaatgat tctaacaaca ggagttgcaa
    13861 aaaaaataga agcaactgaa ataggaatca tagaaattat tatcatattt atactagatt
    13921 taactgaact agtaaacttc ttttgattat tttctgcact taacttagat aacataggat
    13981 acataacaga tactattgaa gctgtaaatg tccctgtaac aaaaccattt aatctatctg
    14041 cataagtaag tgctggaatg cttcctttaa ctaatgttga ggctaaagtt gtatctacca
    14101 atgagttcac ttgattaaca gcaacaccta taaatactgg tgaaagtaat gctagtaatt
    14161 taataaggct atcatcttta aagtttaagt agtgtaagta tttgtagttc gtttttttaa
    14221 caaaaaacat gtaaaagagc agttgaacta ccatagcaac cacagcacca attggaagta
    14281 tgtatggtcc aaatacggta cttaacatta ttgaaataat tattactata ttatagggta
    14341 tacttccaaa tccaactaca ataaagttct ctttaatttg taaaaatgct gacataacac
    14401 tcgtaatacc tatgaatatt attcctatta tcaatatttt agtaaatttt acggtaagta
    14461 aaaacctctc tccttcaaat cctatagcaa atatacttac aagttgcttt gagaaaataa
    14521 ctcctaatat agctacaact atgcatatac caactattat atttaaaaca ttgtttaaaa
    14581 actttagtgc ttgcttttca ccttgtttac tacttatatc ttgatacatt ggaataaaag
    14641 tagtaactat agcagtacct attgctgcaa atataatatt tggtatattc atagctgtta
    14701 aataactctc tgtatataag cctgtaccat aaattgatga taatactaat tctctaccca
    14761 ttccaagaat cttagagatt atagtaacta tcatcaaata aaaagttgct ttagctacct
    14821 tgctcatttt atcactccac ttctaacata cctcttttta atcaagtaaa atttagctca
    14881 ttagatataa ttctatcaac taatttgcct tgcttagccc tatcaaaata taattaacac
    14941 ctatttctta atatatcaca aactacatta ttcttcatat ttttttattt ctccaataag
    15001 ttttacattt ttcctatata aattgtatag cttcaattat attcaaagaa atggagttgc
    15061 tacccgataa ctttaaaagt aaaaaacaga ttttattatc tttttaaact atattctaac
    15121 atattttgtc catattgaga aattttacta aactattatg tactttatta aataaataaa
    15181 ataacagcac acctataaaa tacaagtgtg ctgttcataa acagatttta taaaaaaata
    15241 attcctaagt agagattaac atgctttctc atactctcat atataatgtg tctaaaaata
    15301 ttaataaaaa tgctttaatt gttttaactt acttggatgt cttaattttc ttattgcttt
    15361 agcttctatc tgtcttattc gttctctggt aactccaaat acctttccaa tctgttctag
    15421 tgttttaggg tcatcatcat caattccaaa tctcattctt aaaacttgct gttcttgctc
    15481 tccaagacct gtaagtagtt cttctatctt ttcttttaaa ttatgctgtt caacttcgtg
    15541 tattacaaca tctttaaaat cagcatctga tggtataaat tcaactaaac tactatcctc
    15601 atcttctttt aatggagtat ccaaagatac aacattttta tctcttctta ataattccaa
    15661 cactttgtca acttctaagc cacatgcatc tgcaatctca tctatagttg gctctcttaa
    15721 taatacattt aaaagttctt gtttcttttt ctttacaaaa tttattctct gatgaagatg
    15781 tataggtatc ctaatagtat tttcgcaatc gtcgatatat cttgttatac tttgttttat
    15841 ccaccaagtt gcataagtgc taaatttgta tcctttttta taatcgtact tttctacagc
    15901 ttttataagt cctatatttc ctgcttgaat taaatccaac atatcaatac tatctctttt
    15961 atatctcttt gctatgctca ctaccaacct ataatttgaa tttataaatt tttcttttgc
    16021 tactgaagat gagttgatta tttccttagc cagctctacc tcttctcctg ctgacaacat
    16081 tttgtattcc tctatttcct ttaaatacat tttcatcgca tttgatacat ttgatgaacc
    16141 cacacaaata taattttcat aattattttc ttttttagta tccataatca aaccccttct
    16201 attcatagaa tttgctaaaa caaaaataaa taatttaaac ctacataatc tacaattaca
    16261 taatatccca ttctttaaat gaattgtttt gtatattatg tatacaaatt tataaaaact
    16321 atacctataa tattattcta cttctaacag caatatcctc cttatatata taatttattt
    16381 tattatatgt tgttatattc ttagtttttt gaatgatata tgtctaaaaa aagactgttt
    16441 actaaacagt ctttttttat atatatgctc aatatttaat tttcatgatg atgattacat
    16501 ccacatccac aattttcatc atggtgatga tgttcttcta aatcttttac ctgttgttcc
    16561 atttcatgaa actcttttac cattatatca taagttggaa gagctgcctc agtatcgtat
    16621 tcttcccctc tccaatcagc gtacatcata gcatctccat tagttaaaac caatctacct
    16681 gacatagtta tattatccac ttcttctaaa aattctattt gtttttgtaa aacttctcct
    16741 tctaactcca catcttcatc taaacattgc actatcatta caggtgcata ataatcttct
    16801 tcatctttaa catttacaac aatatctaaa attccttctg caccttcttc aaattctgcc
    16861 aactcaacat ttgtatcaat catatcttga ggtactaata aatcttctat taaatatttt
    16921 attactctat cttttactaa ttcttttgac atttattttt ctccttccga ttctataaca
    16981 ttatcataat catttctata ttatagtata ctacattaat tgttttttca atctcttaca
    17041 aaaattattt ttttattatc ttccttatat tccctttttt attacaaagt tgtaatcgca
    17101 ttgatttaaa aaatagttta tatttagtat aatagaaatg tagcacatat ttttattcaa
    17161 tatattaata aaaaaatata ttgaaaatgt aatgtatgtt aaatctagga ggaatattat
    17221 gaagtttaaa aaacaaatta gttctattgt tgtgtctact atgcttgtac ttgggagtat
    17281 gaacctttct tatgcagacg gtacaaatgt agttacactt ggagctaact tatcagagtc
    17341 tcaaaagcag caaatgctta attactttgg agtaaaaaaa gaccaagtct tagttttaga
    17401 tgtaacaaat gcagaagaaa gacagtattt acaaggtgtt gcaacagagg gtcaacttgg
    17461 aaaagttact atctcttgct catatgttga acctactaaa aaaggaaatg gaattaatgt
    17521 taaaacagca aacttaactt gggtaactag ttcaatgatt gcttcaaccc ttacaacagc
    17581 tggtcttgaa gatgcaaatg ttattgctgc tgctccatat cctgtaagtg gtactggagc
    17641 attgacagga atcatgaaag catttgagga tgcttcagga aagaaacttg atgaaactaa
    17701 gaaagaaatt gcttctgaag aattggtagt tacaggtgac ttaggagatg atatagggca
    17761 agaaaaagca acaggtgtaa tgaatgatat aaaaacagaa attgtaaaga atggtacaaa
    17821 agataccaat caaatagcaa atacaataaa taatgttgta aataattaca atattactat
    17881 tacaccagaa caaaaagaac aaattaaagg tgtaatgaaa aaaatagctg accaaaatta
    17941 cgattacaat agcatgaaaa atacactaga taatgtatca gataatgtaa atgaacaatt
    18001 aaagaaatta ggtgaaagtg ttaagggttc tggtatacta gatactattg gtggatggtt
    18061 tagtggaata ggagactggt tctctggttt attctcaggc ggagataaaa aagatttggg
    18121 aatcttaaat aacactaatg atgagtctct tggctctgat gctgtaataa attctacaga
    18181 aggtgttcaa ataaatccac aaaataatac taattctaac aatgatagtg atacaaatag
    18241 ctcaaaaaat gatacttcaa gtaataatga aaataacgat agttctcaaa caaatgaaaa
    18301 caacacaaca aataattcag aaaatcaatc aaataataat gactcagttg gtttctttga
    18361 aaaaataaaa aattggcttt caggcttatt ttagaaatta aacaaataaa aagaattgcc
    18421 taaaatggaa attttctata aaaggcaatt ctctttattt acaataaatt tttattactc
    18481 actcattttt ttagattttt ctatacatgc acatattgct tttatcacag aagctctaaa
    18541 accttcttct tcaagtactt taactgcttc tatagtagtt ccaccaggtg aacataccat
    18601 atcttttaat tcaccaggat gttttcctgt ctcaagtacc atttttgcag aacccataac
    18661 agcctgtgat gcaaacttat atgcttgtgg tcttggcatt cctgcaatta ctgctgcatc
    18721 tgctatagct tctataaata aaaatacata tgctggtgca gaaccacttg caccaattac
    18781 agcttctata agatactctg gtactacctc agtatttcca aaagaattaa atacttctgt
    18841 aactgcttct aagtcttctt tgtttatatt tttatttata gaaagagaag acatggcttc
    18901 atttacaaga gctggagtat ttggcatagt tctaactatt tttttgtctt ctcctataat
    18961 agactctata tcttttatag attttcctgc tgctattgta actataattt tattgtcatc
    19021 tataaagtct tttatctctt ccaaaatatc atcatatata tctggtttaa cagctacaat
    19081 tactatatca gaggttctag ttacttcctt cgagtctttt gtagtattta ttccaaaatt
    19141 tgcatctatt ctatcgagag ttccttgact atatgctgat gctataacca tattaggttc
    19201 aactaatttt gaatttacta ttccccctat catagcgctt gccatatttc ctgcacctat
    19261 gaatccaatt tttttcactt tagtacctcc ttattgacta atagtaatcg ttaaaattta
    19321 agcttcttta actgcatcag acttttcaaa tggatttggt atacttacta ccaaaatttt
    19381 cactacctta ttagtatagt tgacccaatt atgattgttc ttttcactat tatagtgtat
    19441 tgtgtctcct ggatacattt ctatttgttc atctcccaaa aacactgtaa gagtaccctc
    19501 taatacatac acaaattcct caccttcatg tacgtaacaa caaatttcct cactactctt
    19561 acttggaaga atttcaatta atcttggtag cattgttttt tcctttaaac tagatgataa
    19621 atgataatgt ataaatgttg agttttctac atcaaatact tctttttcat aacttcttaa
    19681 tacagctctt ttatgctctt ttggcttcat aaaaaagtaa gttaattcta catctagtac
    19741 acttgctatt tttcctaagg aatctgttgc cacacttgtt aatcctcttt caagttgtga
    19801 taaaaaacca attgacaagt ttgttttttc actcatatcc ttcagcgtca tttgcttttg
    19861 agttctgagt tgctttattt ttgctcctat gtccttattc aaaaccatca cccctaaata
    19921 attttaattt tttcataata taaatacaaa aatataaata taggtactga acctatcttt
    19981 atttcattta aaaaaatttt tataagtatt actataattt atcaatcttt ttttgtctac
    20041 atttttacga ttatttacga tttatttttc acatatgtat atttaatctt gccaactaaa
    20101 gatacatttt ttataagcat ttactcttta tataataaaa cttaagttgt tcatgtagtc
    20161 ttcttctggt ttaattatta aaatttcaaa ttatattatt atttctacac attattacat
    20221 cctttagtac aattataaca taattttaca atttaatgat atctattcaa tgtctttttt
    20281 tactctacaa catattttat tttagagttt aatactatat atatttttta tatacagcct
    20341 tgtcattttt tagattgtca agagttattg aagtatttta tgtagattta gattttattt
    20401 tctaatttct catttaacaa gaattgctta tgataaaaaa taatatcatc tcaataagat
    20461 tcttgtaaat atatctatat tctaaatata atttcttttt ttgtcaaaat ttcttcattc
    20521 tttaataatt aatttattac ttataaaata aactaattat ctatacaaat tttataattt
    20581 ttaataaaat acacaaaaaa attaattttt atagctcatt tc
//
LOCUS       DAEORM030000063        20390 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.063, whole genome shotgun sequence.
ACCESSION   DAEORM030000063 DAEORM030000000
VERSION     DAEORM030000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 20390)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20390)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 20390)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20390
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.063"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            complement(<1..591)
                     /locus_tag="KRH23_003104"
     CDS             complement(<1..591)
                     /locus_tag="KRH23_003104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HHS5226381.1"
                     /translation="MLNETRKKQLTEVCQDLIRNASYSGQEENVVKAIEENFALLGFD
                     SWSRDRYGNIVGCIKGNKPGKKILFDGHIDTVPVPDASKWSVPPFEARIVDGKIYGRG
                     TSDMKGQVSAMMAAVSYFAEDTNKDFEGELYVAGVVHEEIFEGVSAREISKAVQPDYV
                     VIGESSELNLKIGQRGRGEIVVETFGKPAHSANPEKG"
     gene            complement(921..2135)
                     /gene="dpaL"
                     /locus_tag="KRH23_003105"
     CDS             complement(921..2135)
                     /gene="dpaL"
                     /locus_tag="KRH23_003105"
                     /EC_number="4.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008838 - diaminopropionate ammonia-lyase
                     activity [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopropionate ammonia-lyase"
                     /protein_id="HHS5226382.1"
                     /translation="MREIKWKLNNLPKSEEKEKGIEFLKDEEIAKAKAFHESFPQYEK
                     TPLVKLDNLAKSLGVSGIYVKDESYRFGLNAFKVLGGSYSMGRYLAQRLNTDISELGY
                     DKLTSKEIKEKLGEITFFTATDGNHGRGVAWTANKLGQKSVVLMPKGSSEFRLNKIKG
                     EGADASITDLNYDDAVRLANDYAEADDHGVMVQDTAWDGYEEIPAWIMQGYGTMAKEA
                     IEQLKEYGVDRPTHVFVQAGVGSLAGAVQGYVASIYDECPITVVVEADEADCYYKSAE
                     AGDGKPRFVGGDMPTIMAGLACGEPNTIGFEVLKNYSSAFVSAPDWVSAKGMRILGNP
                     LRGDEKVISGESGAVTTGALVSILESEDLKDLREALKLDENSKVLLISTEGDTDPDKY
                     RDIVWNGECQSK"
     gene            complement(2969..3115)
                     /locus_tag="KRH23_003106"
     CDS             complement(2969..3115)
                     /locus_tag="KRH23_003106"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226383.1"
                     /translation="MHRQAKGFAQNHKVIPAYIGSVGMFNDTKTVFVSPIMKQYVLVS
                     ERII"
     gene            complement(3353..5158)
                     /locus_tag="KRH23_003107"
     CDS             complement(3353..5158)
                     /locus_tag="KRH23_003107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54-dependent Fis family transcriptional
                     regulator"
                     /protein_id="HHS5226384.1"
                     /translation="MLSKLKEFQQEMIKYTETVASVLDVDIEIVDDRLIRISGTGLYK
                     SKINESVVTEGFIYDNVIQTGQELVVLDICDNQLCIECSHYMKCLNKVIIAVPIKYNN
                     RTIGVIGAISTDKTKKVEISAKIDNYLKFVNHICDLISMKIEEHEASKNSSRKMDMMI
                     EIIENVEKGVIILDINSKISYINNIALKKLDIDKNIIENIVNIVSVESSSNGHELLEI
                     DIDNKIYNINAKIIPVYPYINQYDKIIIFDKTYINHKGHGKVNSGWGNSDIESIIGNS
                     EAMLKVKERTKKLAKSNSTVLITGESGTGKELIARAIHAEGSRWNKPFIAINCAAIPE
                     NLLESELFGYIKGAFSGASSGGKVGKFELANEGVIFLDEIGDLSMPLQAKLLRVLQER
                     KFARIGSNKLIDLDIRVIAATNKNLLKLVNEGKFRDDLYYRLNVIPINLPPLRERKDD
                     IEAIMMKFASKYSLELGIQLNKIEENVMNMLINYNWPGNIRELENAVEYMMNLVGDDG
                     IIYKDMLPLDILNYYNINGNIYKNKDVNIIFEDDIVGGIVENQERILSIKELELTYIN
                     KLLNKYGRDTKTKKKIAKDLGIGLATLYRKLEEEQ"
     gene            complement(5554..5931)
                     /locus_tag="KRH23_003108"
     CDS             complement(5554..5931)
                     /locus_tag="KRH23_003108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HHS5226385.1"
                     /translation="MSKVVIATEKAPGAIGPYSQAIQVGNIVSTSGQLPIDMKTGELV
                     SDPKEATKASLDNVKAILEQAGTSMDKIFKTTVFVKDLKDFNDINEVYATYFKENPPA
                     RSCVQVAQLPKDAVLEIEAMAVL"
     gene            6836..7321
                     /locus_tag="KRH23_003109"
     CDS             6836..7321
                     /locus_tag="KRH23_003109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226386.1"
                     /translation="MSKSELTAETTEEMLEVLSGKDYDIACHLHELGKSLDCKIEPKT
                     GARSYKIVYSTKKPKRSLFTIECNEKKWRVKANLFHLNTYKDAVEECSKTIKDSITKT
                     RTCKKCNSKCIGGSSFELDGKSYLTCIGSGHYFANMEEMDWKNLEKLITKENNIMQES
                     V"
     gene            complement(7521..8060)
                     /locus_tag="KRH23_003110"
     CDS             complement(7521..8060)
                     /locus_tag="KRH23_003110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HHS5226387.1"
                     /translation="MSKNVLIVSASPRKGGNSDLLCDQFIQGVLESKNQVEKIFLKDK
                     DINYCTGCGACYEKEANCSQTDDMGEILEKMIGADVIVLATPVYFYTMNAQMKTMIDR
                     TCSRYTEICDKDFYFIVTAADENVADMERTIEGFRGFTSCLNGSKEKGIVYGVGAWNV
                     GDIKGSKAMKQAYEMGKLA"
     gene            complement(8053..8466)
                     /locus_tag="KRH23_003111"
     CDS             complement(8053..8466)
                     /locus_tag="KRH23_003111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HHS5226388.1"
                     /translation="MTISEVSKKYELSADTLRYYERIGLIPPVNRNKSGIRSFTEEDC
                     EWVNFIKCMRGAGLSIETLIEYVAMFQQGSSTIKARKELLIEQRNQLAKRIEEMQKTL
                     ERLNFKIDRYEEGIIEKEKVLKSSRNKKMEAVSYE"
     gene            complement(8502..9623)
                     /locus_tag="KRH23_003112"
     CDS             complement(8502..9623)
                     /locus_tag="KRH23_003112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HHS5226389.1"
                     /translation="MEAKKLGFGLMRLPIKDENDVTTIDMEHLNKMVDTFLERGFTYF
                     DTAYVYHMGKSEIALRESLVKRHKRESFTIATKLPLMALKKKEEQETIFNEQLEKCGV
                     DYFDYYLLHNIGVSHYEVAKKFDSFKFIEEKKKEGKIKNIGFSFHDSAELLDKVLSEH
                     PEVDFVQLQINYLDWDNESIQSRKCYEVAEKHNKPVIVMEPVKGGTLAKIPEKAEKLL
                     NDYNPDMSISSWAIRFAASKDNVMMVLSGMSNMEQLLDNTGYMQNFKPFVQEEYNIID
                     EAVEIINESILVPCTACQYCVEGCPKNIAIPNYFALYNAEKQALNTGFSTQMVYYNNY
                     TKTYGKASDCIECKQCEESCPQHIKIIDALKNVAETFEK"
     gene            10222..11874
                     /locus_tag="KRH23_003113"
     CDS             10222..11874
                     /locus_tag="KRH23_003113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp21"
                     /protein_id="HHS5226390.1"
                     /translation="MNKKNLAILISGMMFFSSSSAIFADNTTKQERLIGKTRYETAVE
                     VSKLGWVQSKTAIIVNGNSIQSALCANPFAKLKNAPILLVNNNSIENSTKAELKRLGV
                     DNVYIVDSGNSISSKVENEIKSLNIKINKIVGNNIYEMSTNVLKEIDKIKKIENVAVV
                     NGLKGLSDAVSIASPAAIHNMPIILVSDENSNDSSINFLNNRSIKKSYIVGGNKILSD
                     NTVKKYPNRERISGSDRNNTNAKIIDKFYKDKKINNVFVAKDGINQENALVDSLSIGV
                     LAAKENSPIMISNGSLVNSQKEFIKNKDIDEITQVGGGYNQKAFEDILKLKNVNIRNK
                     TKKISLIQAKERLKQALPGSNILVCYYDEDDNEYDCKVIKDNILYEIEIDAYSGKIIE
                     IEKDDDLNDNNLGTQNISLDKAKSIALDAVPNGNLVYCKYDAEDNEYEAKVIKNKKTY
                     ELEISAFDGRIVDIDMDNDSDDDFDDNDKNNSNTNDNSSIISAEKAKSIMLDKVPGGK
                     IVKFKYDEDDKEYEGEIIKGKTEYEITINAITGKILEFEIDD"
     gene            complement(12067..12981)
                     /locus_tag="KRH23_003114"
     CDS             complement(12067..12981)
                     /locus_tag="KRH23_003114"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF012770.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HHS5226391.1"
                     /translation="MKRENGEKMNNQFIREDVDFYSNKTRCSSWVYLPNINKKCPVIV
                     MAHGLGGVREMRLDVYAERFAAAGYACFLFDYRNFGASDGNKRQLINVKEQLTDWNCA
                     IDFIKKDDRFDSNKILLFGSSFSGGHVITLSSKRKDILAAISQCPYTNTLATMGTLSP
                     LSTLKTVPLVIFDLLSCVTGYHPVLIKLGDKRGKIAIMAVSDYNGYLEQVPENSNFVN
                     KAPARTLLEFIKYSPSRYTKDITIPIYYAVCRKDTLAPSKATVKCAKLSKKATIKEYD
                     CGHFDIYLGNYFENAIADYIGFFDKNAK"
     gene            13125..13652
                     /locus_tag="KRH23_003115"
     CDS             13125..13652
                     /locus_tag="KRH23_003115"
                     /inference="COORDINATES: protein motif:HMM:NF025636.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HHS5226392.1"
                     /translation="MDKRKLANQKVKNSLLVALLELAQYTKWSNITVTALISKSGVAR
                     SSFYRNFSSIEDIVDYGIMQMNEKYNRENPSLDENFRDKNLMYFKFRFYKEHSDLLLT
                     FHHAQTSQTLLAVINDFVVDAYGDMPSSSISKYELYYYSGAFYNMVIHWLEDGAKESP
                     EDMAEEFIRIANARV"
     gene            14052..14801
                     /locus_tag="KRH23_003116"
     CDS             14052..14801
                     /locus_tag="KRH23_003116"
                     /EC_number="7.6.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHS5226393.1"
                     /translation="MNTILKVNNITKTYNKGQQPSLDKVSFNVSEGEFIGIMGASGSG
                     KTTLLNVLSTIDKPTSGDIFINNINLKSLNDTCAADFRKDNLGFIFQEYFLLDSLTIF
                     ENISVPLTLQKLNPDKIENMVKSLAERFGIASQLNKYPNELSGGQRQRASAVRAIVKH
                     PSILFADEPTGALDSNSATELLHSLQEANEELKTTILMVTHDAYAASFANRILIFKDG
                     HIIKELNKQQNNRHTFYELIIQEIAKLDTKR"
     gene            14814..16841
                     /locus_tag="KRH23_003117"
     CDS             14814..16841
                     /locus_tag="KRH23_003117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHS5226394.1"
                     /translation="MNIFYMAIKNLKKNFSFYSLYLLSVSFVITVFFAFTSFSVNKIM
                     LEKISTDGRVESMCNVISIFLMAFVIFYMAYSNRFFLRRRTKELGIYALLGYHKFTIL
                     SLLTFENILICSGAFIIGLVLGALAHKGIVFGITALLNLSIDNSQIPFFNINAINKTI
                     IFIALVVLVLAISNGKFLYKTSLVKLIRYEKSAEKKLKFRKIPAFIGFIMILSGYCLS
                     LDILRGAKSVWVSIGFYQMGLITMIIIVIGTVLFINSFLPYIMQKSKKNKRTFYTDMK
                     IIAIPNFIYRILSNSKTLIMLTLLSATTLTVSSVMALSLYYPIASVSRIAPSEIEFRV
                     EKNKQIEDVKQIVSQYTSNTDDIIFTQTNIYKVKSSSKDLPFEYEIGTSKNNLSNSNS
                     SKKVISRESGFECISFSDYYTLLKAQNRTKLLKQLTPLRDNECILMKYQPNNDGYSEN
                     GTIYPLLVNGKETPVAVRETSLNNAISFANSVGTLIVNDSIYEQIAQNKLPMTSILSI
                     NGKSIKNNENLYSNISDYLDGSPYLQGYSHRINDLLSINSSTFLLIGFLVVLFFIAVG
                     SILYFNNISAISDSTSDYKILQKMGYDNIQIKKIIKKQVLPFFNIPFLLGILDCIFAT
                     LVYKTALMQNLLGNSFSQYIPVIIAIFLTSVVYLIYYILTIKSCCKIVLKN"
     gene            complement(17071..17271)
                     /locus_tag="KRH23_003118"
     CDS             complement(17071..17271)
                     /locus_tag="KRH23_003118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226395.1"
                     /translation="MLNILKIIVPIGVVTNDKSKYQLSSASNPQNNEIMLFSRTLQEV
                     IYVMSMSNNVEIIKGIMLWIFI"
     gene            17312..18568
                     /locus_tag="KRH23_003119"
     CDS             17312..18568
                     /locus_tag="KRH23_003119"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HHS5226396.1"
                     /translation="MFQGSGYNFRKITDILLLITCIGAIVGAFISNRTYACMYGIQFV
                     VSIISFFYIIFYHLKRVVFVIKSEKKPISISVFITIIGFLTYYFFTLRISNHIGNFGI
                     YLTVLVFFMSIHGIALKENDSFPISTVFNIKQRAIFLFISILVISLVVLFANGNFSII
                     LIAINVLFMLIFLCNIILEFNLRDKKNKVVKNSKYTFALEKLQQEEQLKTEFSNFLHD
                     DILQNLLSIKNMMSKSYRPDVQDIIYETLNNLNTCIRKQMQDYHPVILKNLTVKENYQ
                     NLIESVSSSFPQKNICVSFKCSDTLFLVEPYDILIYRLIKELLTNVYKHSNGSHAWIA
                     LALEKNIIKLNINDNGVKNTSFKTPLDITKITFDTIKHKGIISIKEQVENLGGTISIS
                     DNIPHGVCVQITIPMKGDGSYKYFVS"
     gene            18576..19160
                     /locus_tag="KRH23_003120"
     CDS             18576..19160
                     /locus_tag="KRH23_003120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HHS5226397.1"
                     /translation="MLFAKSLSIALEEYKEIEQFYSTQDIHNLSEMIQDKKIDIVLMD
                     INLRGLSECDGLKVAYNLLETNSTIKIIILTGYDLPVYKHEAKKIGIYGFLNKNISPD
                     SLIDSLLKVYQGVTCFPSENTEVIIEDLTNMEKRILQLICSGKKRKIIADELYISERT
                     LSNHLQHIYDKLDVSSSVEAITKAIKMGYISPVY"
     gene            complement(19349..20275)
                     /locus_tag="KRH23_003121"
     CDS             complement(19349..20275)
                     /locus_tag="KRH23_003121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conserved phage C-terminal domain-containing
                     protein"
                     /protein_id="HHS5226398.1"
                     /translation="MSNSFYQLNSAVLYFNEKRDVNRIRFNHYVMRKENIQRLKGTLP
                     RGQFMMTVRKAASDLDVSISTISRLVNEFIDLGILRLISRGVKGNCCSVYSYVCSESS
                     NAEIVTKNGDIFKNIEKYIDATINNNQKTMKYKHRDELFKNSNTNLYSRINQESIDKD
                     YDLIIHTGYETENETKKKELLKNNLNKKNLNKNTFENSDEDLTEDSTYKNPESIHEII
                     IRKLNSESGKNFKADLSITKALIDKRLKEGYSLEDFYKVIEAKVRRWRYTDMEIYIEP
                     TILFGYEFESYLNEESSLSACNYGDMCYEDMY"
BASE COUNT         6993 a         3212 c         2483 g         7702 t
ORIGIN      
        1 acctttttct ggattagcag agtgagctgg tttaccaaaa gtttctacta ctatttctcc
       61 tctacctctt tgacctatct ttaggtttaa ttctgaagat tcacctatta caacataatc
      121 aggttgaaca gccttactta tctctctagc tgaaacacct tcaaatattt cttcatgaac
      181 aacacctgct acatacaatt caccttcaaa gtctttgtta gtatcttctg caaaatatga
      241 aacagcagcc atcatagcac ttacttgccc cttcatatca gaagttcctc taccatatat
      301 tttcccatct actattctcg cttcaaaagg aggaacactc catttacttg catctggaac
      361 tggaactgta tctatatgcc cgtcaaataa tattttttta cctggtttat ttccttttat
      421 acatcctact atatttccat atctatctct tgaccaacta tcaaaaccta gtaaagcaaa
      481 attttcttct atagctttta ctacgttttc ttcttgacct gaataactag catttcttat
      541 taagtcttgg catacttcag ttaattgttt ttttcttgtt tcatttaaca ttttgatatt
      601 cccccatata atttttaatt tgttgacgtt ttattttgat atttcacttt tttaatttat
      661 tagcatttca cttaatctat tgatttttta tttctttata ttttatttat taaattttta
      721 tttagacttt attttaattt tatttggttt ttattttgaa tttttcattt gctttacttt
      781 tttatttgct ttactttttc atttatttag atttttcatt tgttttagtt tttattttat
      841 ttaaagtttt cacttattta agtttttatt ttccttaaat ttttcattta tttgttaaga
      901 ttttcttttc cttaagtctt ttatttactt tggcattcac cattccaaac tatatctcta
      961 tatttatcag ggtcagtatc tccttctgta cttattaata atactttaga gttctcatct
     1021 agtttcaaag cttctcttaa gtcttttaaa tcttcacttt caaggattga aactaatgct
     1081 ccagttgtaa ctgctccaga ttctccagag attactttct catctcctct tagagggttt
     1141 cctaatattc tcataccttt agcagatacc cagtctggtg ctgaaacgaa tgctgatgaa
     1201 taatttttta acacttcaaa acctatagtg tttggttctc cacaagcaag ccctgccatt
     1261 atagttggca tatctcctcc aacaaatctt ggttttccat ctccagcttc tgctgattta
     1321 tagtaacaat cagcctcatc agcctctact actactgtta ttgggcattc atcatatatt
     1381 gaagcaacat acccttgaac tgcaccagca agtgaaccaa ctcctgcttg aacaaatacg
     1441 tgtgttggtc tatctactcc atattctttt aattgttcta tagcttcttt agccatagtt
     1501 ccatatcctt gcattatcca tgctggtatt tcttcatatc cgtcccatgc tgtatcttga
     1561 accattactc catggtcatc agcttctgca taatcattag ctaatcttac tgcatcatca
     1621 tagtttaagt ctgttatact agcatctgca ccttctcctt tgattttatt taatctaaat
     1681 tcagaagaac cttttggcat taatacaaca gatttttgac ctaatttatt agctgtccaa
     1741 gcaactcctc taccatgatt tccatctgtg gctgtaaaga aagttatttc tcctaatttt
     1801 tcttttattt cttttgaagt taatttatca taccctaact cagatatatc tgtatttaat
     1861 ctttgagcta agtatctacc catagagtaa gaaccaccta aaactttaaa tgcatttaaa
     1921 ccaaatctat aagattcgtc tttaacatat attccgctta cgcctagtga ttttgctaag
     1981 ttatctaatt taactaaagg agtcttttca tattgtggaa agctctcatg aaaagcttta
     2041 gcctttgcaa tctcttcatc ttttaaaaat tcaattcctt tttctttttc ctctgattta
     2101 ggtaagttat ttaatttcca ttttatttct ctcatttatt ttatattccc ctttcaaatt
     2161 tttcggtgtc attttaattt tttatctttg tgccttatag caaagcaatt accgtgccaa
     2221 tattatttat tctaaaaaca atttttttat gttggaatta catactttta taaaatttct
     2281 ttaaagttta taaattttga gtgtgaaaaa taagatttat aaaagaaaaa attctcatat
     2341 tgggaaattt ttatcaatac gagaattatc aattcgagaa atcgtttatt tatcttaatt
     2401 cttcctttat tatgctctta ttttttatat gtctattgtt ttgtcagata tattactact
     2461 tttattttct ataaatatat ggctataacc ttcttacgca taaactctat aaatttatat
     2521 actttatatt ctttattacc caaagcctcc aaaatggctt aaatcttttc atagcttctt
     2581 acagaagttt acatggtcgt ccccccaata agcaaaagtg caatatgtgt accattgtgc
     2641 cctacttgcg actattgagc tgtcgaaatt cgcaacttcg catttatctg atgaaatgca
     2701 ctatgcaaaa tattcataac atccacaaca gagttaaagt tacctattca tattcactgt
     2761 aaaaatttct tccacaggaa atgtaatttt aaccaatcct attgagacaa actcaccact
     2821 tatttttttg aactcacgca gtaatacatc acttgcccga aaaaaagcct cactttcatc
     2881 atctccagta agtgctattg tgcaatgggg tacccaacga ttggggtggt accattccca
     2941 accatttgaa tcaaaatctt gtagtacctc atataattct ctctgaaact aatacatact
     3001 gcttcattat aggtgataca aacaccgttt tagtatcatt aaacatgcct actgaaccaa
     3061 tgtaagcagg tattacctta tggttttgtg caaacccttt agcttgtcta tgcaacaagc
     3121 ctcatccaca tcattgaaac aagccaaagt aagatgaggt cttgttttcc attctaagta
     3181 cttcgtacta attttttcat cagcgatttt tttagataaa tcaaaaagtt gcttttccgt
     3241 ttttttatca taatatagct ctatcgcata ttgcataata acaccttcac cataaagtaa
     3301 aaatacctat ctataaaaac acacaaatac ctatcatttc aatattatat tactactgtt
     3361 cctcttccaa ttttctatat agtgtagcca aacctatgcc taagtctttt gctatcttct
     3421 tcttcgtctt tgtatctctt ccatacttat tcaacaactt gtttatgtaa gtcaactcta
     3481 attctttaat tgaaagtatc ctttcttgat tctctactat ccctccaact atatcatctt
     3541 caaatattat atttacatcc ttatttttat aaatatttcc attaatatta taatagttta
     3601 aaatatctaa tggaagcata tctttatata ttattccatc atctccaacc aaattcatca
     3661 tatattcaac tgcattttcc agttccctta tatttcccgg ccaattatag ttaatcaaca
     3721 tattcattac attttcttct attttattta actgaatacc taattctaaa gaatatttag
     3781 aagcaaactt catcattatt gcctcaatat catcctttct ttccctaaga ggtggcaaat
     3841 ttataggaat tacattcaat ctatagtata aatcatccct aaacttacct tcatttacta
     3901 atttcaataa gtttttattt gtagcagcaa tcactcttat atctaaatct ataagtttat
     3961 ttgacccaat tctcgcaaat tttctctctt gtaaaactct aagtaacttt gcttgtaaag
     4021 gcattgacaa atctcctatt tcatcaagaa atataacacc ttcatttgca agttcaaatt
     4081 tacctacttt acctccacta ctagctccac taaatgcacc ttttatatag ccaaatagct
     4141 cactttcaag gagattttct ggaatagcag cacagtttat cgcaataaat ggcttgttcc
     4201 atctgctacc ttcagcatgt atagccctag caattagctc tttacccgta ccactttccc
     4261 cagttataag tacagttgaa tttgactttg ctaatttctt agttctctct tttactttta
     4321 acattgcttc tgaatttcca attatagact ctatatcact atttccccaa ccactattca
     4381 cttttccatg tcctttatga ttgatatatg tcttgtcaaa tattattatt ttgtcgtatt
     4441 gatttatata tggatatacc ggaattattt tggcatttat attataaatt ttgttatcaa
     4501 tatcaatttc tagtaattca tgtccatttg aggaagattc aacagatact atatttacta
     4561 tattttctat tatattttta tctatatcta atttttttag agctatattg tttatataag
     4621 atattttgct atttatgtct agtattataa cgcctttttc aacattttca atgatttcta
     4681 tcatcatatc catttttcta ctgctatttt ttgacgcttc atgttcttct attttcatag
     4741 aaattaaatc gcatatatga ttgacaaatt ttaaataatt atctattttt gcacttattt
     4801 ctactttttt agttttatct gtactaatag caccaattac tcctatagtt cgattattat
     4861 actttattgg aactgctatt attactttat ttaggcattt catgtaatgg gaacattcta
     4921 tacaaagctg attatcacat atatccaata cgactaattc ctgacctgtc tgtataacat
     4981 tgtcataaat aaagccctca gtaacaacgc tttcatttat ctttgattta tacagacctg
     5041 taccactaat tcttattaat ctatcgtcaa ctatttcaat atctacatct aacacactag
     5101 ctactgtttc agtgtatttt atcatttctt gttgaaattc ttttaattta cttaacatag
     5161 tttcccccat tagaatttaa tttaccaaat tatcagttta gctatatttt aacatatagt
     5221 cactctttaa aatatatata aaacattact tatttatata tttgcgttaa aacagacaat
     5281 attaatttat aaaaagtttg ttttatatag taaccttaat tataatatgc agacaataaa
     5341 ataaatcaca atacaataat aaaaaaaagc tttcctcata taacaaatat atttttgaca
     5401 taaaaatata cattatatga gaaaagctca atagttaaat atttagatag atttttatat
     5461 agactttttt aatataaact tttttaattg tagacttttt ttattagttt ttaattttta
     5521 ttagttttgt tattggtttt attgttataa tacttataat actgccattg cttcaatttc
     5581 taaaactgca tcttttggta attgagcaac ttgtacgcat gaccttgctg gtggattttc
     5641 tttaaaatat gtagcatata cttcattaat atcattaaaa tcctttaaat cttttacgaa
     5701 tactgtagtc ttaaatattt tatccatact tgtaccagct tgttctaata ttgcttttac
     5761 attatctaaa gaagcttttg ttgcttcttt tgggtcagat actaactcgc cagtcttcat
     5821 atctattgga agttgacctg atgtagaaac tatgtttcca acttgaattg cttgagaata
     5881 tggtccaatt gctcctggag ctttctctgt agctattact acttttgaca tgacttcacc
     5941 tcctattatt aagttatatt tacaggaaaa taaaatttcc taaacaccaa tattaatacg
     6001 aacctttaga ttaaatttca aatctaaaac ttcaaataat caatacttag atgattatgt
     6061 ttatttgtgt cttgttaact tttattaaag caattaacgt gccaaacttt atttatatat
     6121 aaaattttgt gaagtcattc aaaatagtta cttctgaatt ttttcgtaaa aaaacgctct
     6181 aaaattactt ttttatgatg tcaatttttt tctcatatct agaaatttac caacatgaga
     6241 attcttgttt tgagaattta cagattaaag ttatttttta accttaaatt ctgaacctcc
     6301 catgactaaa gtcacagggt tcctgcttca tagaattttg cataatcaag ttattacata
     6361 tgaaagaact atagttgaca atcccactat tataaataat aaaaccttta tccatacctt
     6421 atttacccta gttatcatag agcctattga aaatataaca gctaaatata ataataacca
     6481 aaaaattatc aatatctacc actgttgctg aaaatccaaa aaactacctt ttgatagtat
     6541 tacttaacaa tctaattaat ctcataataa atttacaact tataaataaa ttgttatatt
     6601 ggccgtatct caacaacttt ctcctttcct agttttaaat cttttataga attgtaccac
     6661 gtctaagtaa attttcatac tattaagtct tatttctaat aaatcattag ctctcattct
     6721 atgcccaata atgtaagatt gcagtaattt tattgatttt catagtttta tttaatatac
     6781 ttatattaat tattttcata tgaaattatt atttatatag ggggattttt ttaatatgag
     6841 caaaagtgaa ttaacagcag aaacaacaga agaaatgtta gaagtactaa gtggtaaaga
     6901 ttatgatatt gcatgtcatt tacatgaact tggtaaatca ttagattgta aaattgaacc
     6961 aaaaacaggt gctcgttctt acaaaatagt atattcaact aagaaaccaa aacgtagctt
     7021 atttactatt gaatgtaatg aaaaaaaatg gagagttaaa gcaaatcttt ttcatctaaa
     7081 tacatataaa gatgctgtgg aggaatgctc taaaactatt aaagatagta taactaaaac
     7141 tcgtacttgt aagaaatgta attcaaagtg tattggaggt tcttcgtttg aattagatgg
     7201 aaagtcttac ctgacttgca taggaagtgg tcattatttt gcaaatatgg aagaaatgga
     7261 ttggaaaaac ctagaaaaat taattactaa agaaaataat attatgcagg aatctgtata
     7321 gttttttaag ggtaattatt aaaatatatg agtaacaaca gatacttaaa taggcataaa
     7381 aaaataaagg gtataataag gatatagaat aaaaataaat gatatagcac aaagaggctg
     7441 tctcaaaata cagataagcc tctttttatt gttgaaatga taagaatata ttcaatttta
     7501 tacaatttta tacaaacata ctacgccaac ttacccattt catatgcctg tttcattgcc
     7561 ttacttccct taatatcacc tacattccaa gcacctacac catatactat acctttttcc
     7621 ttagagccat ttagacatga tgtaaatcct ctaaatcctt ctattgttct ttccatatca
     7681 gccacatttt catctgctgc tgtaacgata aaatagaaat ctttatcaca aatttcagta
     7741 tatctagagc aagttctatc aatcatagtt ttcatttgcg cattcatagt ataaaaataa
     7801 actggagtcg ctaaaacaat cacatctgcc ccaatcattt tttcaagaat ttctcccatg
     7861 tcatctgtct gtgaacaatt tgcttctttt tcataacaag caccacatcc agtacaatag
     7921 ttaatatctt tatcttttaa aaatatcttc tccacttgat ttttagattc taatacccct
     7981 tgtataaact ggtcacacaa taaatcagaa tttccacctt ttctaggact agctgatact
     8041 attaatacat ttttactcat aagatactgc ctccattttc ttatttctac tgctctttaa
     8101 tactttttct ttctcaataa taccttcttc atatctatca atcttaaaat ttaatcgttc
     8161 caaagttttt tgcatttctt ctattctttt tgctagttgg tttctctgct ctattaaaag
     8221 ttcttttcta gctttgatag tactgctccc ttgttgaaac atagctacat actcaattaa
     8281 tgtctcaata gaaagacctg cacctctcat acactttatg aaattaaccc actcacaatc
     8341 ttcttctgta aaagacctaa ttccactttt atttctattt acaggtggta ttaaaccaat
     8401 tcgttcataa tatcgtaaag tatccgctga aagctcgtat tttttactaa cttctgaaat
     8461 cgtcatacat atcttctcct cttgatattg tatagattga attatttctc aaaggtttct
     8521 gctacattct ttaaagcatc tataatttta atgtgttgag gacagctttc ttcacattgt
     8581 ttacattcaa tacaatctga ggcctttcca taagttttag tataattatt atagtagacc
     8641 atctgtgttg aaaatccagt attaagagct tgtttttctg cattgtacaa cgcaaaatag
     8701 tttggaatag cgatattttt tggacagcct tctacacaat actgacaggc agtacaagga
     8761 actaaaattg attcgttgat aatctctact gcttcatcta taatattata ttcctcttgt
     8821 acgaatggtt tgaaattttg catatatcct gtattgtcta ataattgttc catatttgac
     8881 atcccactta agaccatcat aacattatct ttacttgctg caaaacgtat tgcccaagat
     8941 gaaattgaca tatctggatt gtagtcattc aataatttct ctgctttttc tggtatcttt
     9001 gcaagtgtac ctccttttac tggctccata acaattacag gcttattatg cttctctgcc
     9061 acctcgtagc attttctaga ttgtatgctt tcattatccc aatccaaata attaatctgt
     9121 aattgcacga agtctacttc tggatgctca ctcaagactt tatccaataa ttctgcacta
     9181 tcatgaaaag aaaaaccaat attctttatt tttccttctt ttttcttttc ttcaataaac
     9241 ttaaagctat caaatttttt agctacttca taatgtgaca cgcctatatt gtgtaaaaga
     9301 tagtagtcaa aatagtctac accacatttt tctaattgct cattaaaaat ggtttcttgc
     9361 tcttcttttt tctttaaagc cattaatgga agttttgtag ctatagtaaa actctctctt
     9421 ttgtgtcttt ttactagaga ttctctaagt gctatctcac tttttcccat gtgatacaca
     9481 taggctgtat caaaatatgt aaatcccctt tctaaaaaag tgtctaccat tttatttaaa
     9541 tgttccatat caatagttgt aacatcattt tcatctttta ttggtaaacg cattaatcca
     9601 aatcctaatt tttttgcctc cattgtttta cttccccctt taaaacttgt ttgttttttc
     9661 tctctacttt aactattctt acaagtatat aattcttgta taattatact ttactacttg
     9721 gagttaactt caagtcaata gattttttta tttttaagac aaatattata aaaatacagt
     9781 tctttaatat taatccattg catgtttctt tcaccctcca attctcaaac ttcacaaact
     9841 ccaacatgta aagaaatata tactttaaga aattcagtcc attaatatta ctacaaatac
     9901 tttttagata tgtttaaaaa gaaatttcac ctaaaatgtt tataaaagat ttagaaatag
     9961 gtcttgtgtc tattttaaaa tatataaaac agtggtaaag acttatttat aagataaaaa
    10021 atgaatagtg tatacccttt ttaaaaagtt ttttcctttt tatatttgtg atacaatgtt
    10081 aaatataaaa aggaaaattt tgtattaaag aaatcttatt tgttgatttt gtaacttcaa
    10141 actcagcatc aatttgattt taagattata ttttattaag tatgctaaat aacaaatttt
    10201 taaagattgt gaggtaaaaa tatgaataag aaaaatttag ctatattaat atcaggtatg
    10261 atgttttttt ctagttcttc agcaattttt gcagacaata ctacaaagca agaaagatta
    10321 ataggtaaaa caagatatga aacagcagta gaagtaagta aattgggatg ggttcaatca
    10381 aaaacagcca ttatagttaa tggtaattct attcaaagtg cgctttgtgc aaatccattt
    10441 gctaagctaa agaatgcacc tatactttta gtaaacaaca acagtattga aaattcaact
    10501 aaggctgagc ttaaaaggct tggtgtagat aatgtgtaca ttgtagatag tggaaatagc
    10561 atttcttcta aagtagaaaa tgaaataaaa tcacttaaca taaaaataaa taaaatagta
    10621 ggaaacaata tatatgaaat gtctacaaat gtacttaaag aaatagataa gataaaaaag
    10681 atagaaaatg ttgcagttgt aaatggacta aagggactat ctgatgcagt tagtatagct
    10741 tctccagcag caatacataa tatgcctata atattagtat cagatgaaaa cagcaatgat
    10801 agtagtataa atttcttaaa caataggtct ataaaaaaat cttacatagt tggaggaaat
    10861 aagattttat cagacaatac agtaaagaaa tatccaaaca gagaaagaat cagtggttca
    10921 gatagaaaca atactaatgc aaaaattatt gataaatttt ataaagataa aaaaataaat
    10981 aatgtatttg tagctaaaga tggtattaac caagaaaatg cattagtaga ttcattatca
    11041 ataggagtac tagctgctaa agaaaattct cctataatga tatctaatgg tagccttgta
    11101 aatagtcaaa aagaatttat taaaaataaa gatatagatg aaataacaca agtaggagga
    11161 ggatataatc aaaaagcatt tgaagatatt ttaaaactaa aaaatgtgaa cataagaaat
    11221 aaaactaaaa aaatatcttt aatacaggct aaagaaagat taaaacaagc tcttccagga
    11281 agcaatattt tagtttgtta ttatgatgaa gatgataatg aatatgactg caaagttata
    11341 aaggataata tcctatatga gatagaaatt gatgcctact ctggtaaaat aatagaaatt
    11401 gaaaaagatg atgacttaaa tgataataat ttaggtacac aaaatatatc attggataaa
    11461 gctaagtcta tagcattaga tgctgttcct aatggtaatt tagtctattg taaatatgat
    11521 gctgaagata acgaatacga ggctaaagta ataaaaaata agaaaacata tgaattagag
    11581 ataagtgcat ttgatggaag aattgtagat attgacatgg acaatgattc tgatgatgac
    11641 tttgatgata atgataagaa taactctaat actaatgaca acagttctat tattagtgct
    11701 gaaaaagcta aatcaataat gctagataaa gtgcctggtg ggaaaatagt aaaatttaag
    11761 tatgatgaag atgacaaaga atatgaaggt gaaataataa aaggaaaaac tgaatatgag
    11821 ataacaatta atgcaattac tggtaaaata ttagaatttg aaatagatga ttaataaaaa
    11881 tagtagaata ataaattact tctaataaca atttctatat aaaaaacact gtaaatccgc
    11941 atgataacta aatttatgcg gatttttgtg tttctgattt agttttttaa aataatttta
    12001 tttaacaccc atttagtccc tgtatgtaac aagaacttac aaaaaatata atgagttgta
    12061 taagaactat tttgcgtttt tatcaaaaaa accaatataa tctgctattg cattttcaaa
    12121 ataatttcct aaataaatat caaaatgtcc acagtcatat tctttaatgg ttgctttttt
    12181 tgaaagttta gcacacttta ctgttgcctt gctaggtgct aatgtatcct tcctacaaac
    12241 cgcataatat attggtattg taatatcttt ggtatatctg cttggtgaat attttataaa
    12301 ttctaagaga gttcttgcag gtgctttgtt tacaaaattt gaattttcag gaacttgttc
    12361 taaatatcca ttgtagtctg aaacagccat tatggctatt ttcccacgct tatcccccaa
    12421 tttaatcaat actggatgat atcctgtaac acaagataaa aggtcaaata ttactaaagg
    12481 tactgttttt aaggtagata atggtgagag tgttcccatt gtagccaaag tgtttgtata
    12541 tggacactgc gatatggctg caagaatatc cttacgcttt gatgatagtg taataacatg
    12601 tcctccacta aacgaacttc caaacaataa tattttatta ctatcaaatc tatcatcttt
    12661 ttttataaaa tcaatggcac aattccaatc tgtaagctgc tcttttacat ttataagttg
    12721 tcttttattt ccatcacttg caccaaagtt acgataatca aataaaaaac aggcataccc
    12781 agcagcagca aatctttctg catatacatc caatcgcatt tcgcgtactc cccccaagcc
    12841 atgtgccatt acaatgactg gacatttttt atttatattt ggcaaatata cccatgaact
    12901 gcatctcgtt ttatttgagt aaaagtcaac atcttcacgt ataaattgat tattcatttt
    12961 ttctccattc tctcgcttca cacgagcaaa tatattttat taaattaaaa ttgacatcta
    13021 cattctttat atgatatggt acattatgta tctgataaaa attgtatcat atctaacaat
    13081 taagtcaatc acataacctg aaacaaaaca aggagaaatg tctcatggat aaaagaaaat
    13141 tagcaaatca aaaagtaaaa aatagtttgt tagtagcact tttagaatta gcacaataca
    13201 caaaatggtc taacattaca gtcacagcac taatttcaaa atctggtgtt gcaaggtcat
    13261 cattttaccg taatttttca tcaattgaag atattgttga ttatggtatc atgcaaatga
    13321 atgaaaagta taaccgagaa aatccatcac ttgatgaaaa ttttagagat aaaaatctga
    13381 tgtatttcaa atttcgattt tataaagaac attcagacct tttattaact tttcatcatg
    13441 cacaaacatc ccaaacattg cttgcagtga ttaatgactt tgttgtagat gcttatggtg
    13501 atatgccttc aagctctatt tcaaaatatg aattatacta ctactctggt gcgttttata
    13561 acatggttat tcattggtta gaagatggcg ctaaggaaag tccagaggat atggcagagg
    13621 agtttattcg tatagcaaat gcacgtgttt agatatcata tatatttgga ttgatttcta
    13681 aatacatata tgtaaattat aataatagtt gcttttgtat caatgatgtg tgtatccata
    13741 attaaagtct accatcaaag atacttcaaa ttttttccac tagtctttgt tttttcttta
    13801 taaagactta tgaaaacact ataatatgat tttagtatat taaatcaata aaatatattt
    13861 tattaattat attaaagcca taaatactga attttcccgt atttatggct tttcttttat
    13921 tttttaatta gtatcctcca tcatattgta atacaaataa tttacacaaa attattgcgt
    13981 gatttactca tgaagaaaca ataaggttaa tatataattt gactatatta agacgaaagg
    14041 agacatatac aatgaataca atattaaaag taaataacat aactaaaact tataataaag
    14101 ggcaacagcc gagtttagat aaggtatcct ttaatgtatc agaaggtgaa tttataggta
    14161 taatgggagc ttctggctct gggaaaacaa ctctacttaa cgtattatct acaattgata
    14221 aaccaacaag tggagatatt ttcataaata atataaattt gaaatcgctt aatgacactt
    14281 gtgctgctga ttttcgtaag gataatttag gctttatctt tcaagagtat tttttactag
    14341 atagtcttac aattttcgag aatatttcag tacctcttac acttcagaaa ctcaatccag
    14401 ataaaataga aaacatggta aagagtctag ctgaacgatt tggcatagct tctcaattaa
    14461 ataaataccc aaatgaatta tctggtgggc aaagacagag agcttcagca gttagagcaa
    14521 tagtaaaaca tcctagtatt ctctttgcag atgaaccaac aggagctttg gattctaatt
    14581 cagctactga actactccac tcactacagg aagcaaatga ggagttgaaa acaacaattt
    14641 taatggtaac acatgatgcc tatgcagcaa gttttgcaaa tagaattttg atttttaaag
    14701 atggtcatat cattaaagaa ttaaataaac aacagaataa tagacataca ttttatgagt
    14761 tgattattca agaaattgca aaattggata ctaaaagata ggaggataat ttaatgaaca
    14821 ttttttatat ggcaataaag aatcttaaaa aaaacttttc attctattct ctatatctac
    14881 tttcagtctc ttttgttatt actgtatttt tcgcatttac ttcattttct gttaataaga
    14941 taatgctaga aaaaatttca actgatggta gagttgaatc tatgtgtaat gttatttcga
    15001 tatttttgat ggcatttgtc atcttctata tggcatactc aaatcgattc ttcttgagac
    15061 gtcgtacaaa agaattaggt atatatgctt tacttggata tcataagttt acaatattat
    15121 cactacttac ctttgaaaat atattaattt gtagtggagc ttttattatt ggattggtat
    15181 taggagcatt ggcacataag ggtattgtct ttggaattac agcactactt aatttatcaa
    15241 ttgataattc acagatacca ttttttaata taaatgcaat aaataaaaca attatcttta
    15301 tagcattagt tgttttagtc ttagctatat caaatggtaa atttctttat aagacttcac
    15361 ttgtaaaatt gataagatat gaaaaaagtg cagaaaaaaa attaaagttc agaaaaattc
    15421 cagcctttat agggtttatt atgattttaa gtgggtattg tttatcacta gatattcttc
    15481 gtggagctaa atcagtatgg gtaagtattg gattttatca aatgggcttg ataactatga
    15541 ttatcattgt aattggtaca gttctcttta tcaattcctt tcttccatat attatgcaaa
    15601 agagtaaaaa aaataaacgt actttctaca cagatatgaa gataatagct attccaaact
    15661 ttatctatcg tatactttca aactctaaaa ctctaattat gcttacatta ctctctgcta
    15721 ctactttgac agtttcaagt gttatggcac tgtccttata ctaccctatt gcatctgttt
    15781 cgcgtattgc accttcagag atagaattta gagtagaaaa aaataaacaa atagaagatg
    15841 taaaacaaat tgtcagtcaa tatacgtcta atacagatga tattattttt acacagacaa
    15901 atatttataa ggtaaaatct tcatcaaaag accttccatt tgaatatgaa attggtacat
    15961 ctaagaataa tttatctaat agtaattctt ctaaaaaagt tatttcaaga gaatcaggat
    16021 ttgaatgtat atctttttct gattattata ctttattaaa ggcacaaaat cgaacaaagc
    16081 tactaaaaca acttacccct ttaagggata atgaatgtat tttaatgaaa tatcaaccaa
    16141 ataatgatgg atatagtgaa aatggaacga tttatccatt acttgttaat ggtaaagaaa
    16201 cacctgtagc tgtaagggaa acatcattaa acaatgctat ttcttttgcc aatagcgttg
    16261 gaacacttat cgttaatgat agtatatatg agcaaatagc acaaaataaa ttaccaatga
    16321 caagcatttt aagtattaat ggtaaatcaa ttaaaaataa tgaaaattta tatagtaata
    16381 tttcagatta tttagatgga agcccttatt tacaaggata ttctcacagg ataaatgatt
    16441 tattatcaat taatagttct acatttctgt taatcggatt tcttgtggta ttattcttta
    16501 ttgctgttgg aagtatttta tactttaaca atatatcagc aatttcagat tcaacatctg
    16561 attataagat tttacagaaa atgggttatg ataatataca aattaaaaaa attattaaaa
    16621 aacaagtatt gccatttttt aatattccgt ttttacttgg tatattggac tgtatatttg
    16681 ctaccttggt ttataagact gctttgatgc agaatttact tggaaattca ttttcacaat
    16741 acatacctgt gattattgca attttcttaa cttctgtagt gtatttgata tattatatac
    16801 ttactattaa atcctgttgt aaaattgtat taaaaaatta atatttacca aatcgtcaag
    16861 cttagaggtg tgacgatttg gtatacttca tttataagta tttgatataa tttaaaatta
    16921 tagattctta ggtttgattt agtcataaaa tcaatataat taactcataa ggaggtgtat
    16981 aagattgaca aattttaatt taaaaatact atttttagga aactacattc tatcacttct
    17041 cttcatggga atatctacaa gcactgaaac ttatatgaat atccaaagca ttattccctt
    17101 aataatttca acattattac tcatagacat cacatatata acctcttgta atgtccgaga
    17161 aaataacatt atttcattgt tttgtggatt actagcacta gacagttggt atttactctt
    17221 atcatttgta accacaccaa taggcactat tatttttaaa atattaagca cagttatagt
    17281 ttatgtctct attaaattta tatttttatt tttgtttcaa ggtagtggat acaatttccg
    17341 taagataaca gacattttat tgcttatcac ctgcattggt gcaattgtag gagcatttat
    17401 ttctaacaga acgtatgctt gtatgtacgg aatacagttt gttgttagta taataagctt
    17461 tttctatatt attttttatc atttgaaaag ggttgttttt gtcataaaaa gcgaaaaaaa
    17521 gcctatatcg atttcagtat ttataacaat tataggattc cttacttatt atttttttac
    17581 actaagaata tcaaatcata ttggtaattt tggaatctat ctaactgtat tggtattttt
    17641 tatgagtatt catggtattg cacttaaaga aaatgatagt tttcctattt caacagtttt
    17701 taacataaaa caaagggcta tatttctttt tataagtatt ttagtaatta gcttggtcgt
    17761 actatttgcc aatgggaatt tttctataat attaatagct ataaatgttt tatttatgct
    17821 tattttcctc tgtaacatta ttttggagtt taaccttaga gataaaaaaa ataaagtagt
    17881 taaaaatagc aagtatactt ttgcattaga aaaattacaa caagaagaac aactaaaaac
    17941 agagttttct aattttttac atgatgacat attacagaac ctgctttcaa taaaaaacat
    18001 gatgagtaag tcatatcgcc cagatgttca agatattata tatgaaacac ttaacaatct
    18061 aaatacatgt ataaggaagc aaatgcaaga ctatcatcct gttattttaa aaaatttaac
    18121 agtaaaagaa aattatcaga atttaattga aagtgtttct tcatcctttc cacaaaaaaa
    18181 catttgtgtt tcatttaagt gttctgatac tttattctta gttgaaccat atgatatatt
    18241 gatatatcga ctgattaaag aattattgac aaatgtgtat aaacattcaa atggtagcca
    18301 tgcatggata gctttagcac tagaaaaaaa tataataaaa ttaaatatta atgataatgg
    18361 tgtgaaaaat acatctttta aaacaccttt agatataact aaaattactt ttgatacaat
    18421 aaaacacaaa gggattatat caattaaaga acaagtggaa aatctaggag gaacgataag
    18481 tatttctgat aatatacctc atggagtttg tgtacagatt acaatcccta tgaaaggaga
    18541 tggttcttat aaatattttg ttagttgatg accatatgct ttttgctaaa agcttgtcaa
    18601 ttgcactaga agaatacaaa gaaatcgaac agttttattc cacacaggac atccataatc
    18661 tttcagaaat gattcaagat aaaaaaatag acattgtctt aatggatata aaccttagag
    18721 gcttaagtga atgtgatggc ttaaaagtag cttataattt attagagact aattcaacta
    18781 ttaaaataat aatcttgact ggatacgacc tcccagttta taaacatgag gctaaaaaaa
    18841 taggtatcta tggattccta aataagaata ttagccctga tagtttaatt gattcattat
    18901 taaaagtcta tcaaggggta acttgttttc catctgaaaa tactgaagta attattgaag
    18961 atttaactaa tatggagaaa agaattttac agcttatctg tagtggtaaa aaaagaaaaa
    19021 taattgctga tgaattgtat ataagtgaaa gaacattatc aaatcattta caacacatat
    19081 atgacaagct agatgtttca tcatcagttg aggctattac aaaagctatt aaaatgggtt
    19141 atatttctcc agtatattaa aaaaagtgag tgtctcaaaa taaatcttct aactcataaa
    19201 gcactctcct ttgtattaaa tcaaatatat tttcatcatt taaacaatta agaagaggct
    19261 tctctctatt ttgagacaac tccattttaa tacactattt atattcatat ataaacatat
    19321 tttaaacaac taaaaagcaa ctaatatctc aatacatatc ttcataacac atatcaccat
    19381 aattacaagc agataaagaa ctctcctcat ttaaatacga ctcaaattca tacccaaaca
    19441 gaattgttgg ttctatatat atttccatat ctgtatatct ccatcttctt acctttgcct
    19501 ctataacctt gtaaaaatct tctaaactat acccttcttt taatctttta tctataagtg
    19561 ccttagttat actcaaatca gctttaaaat tttttcctga ttcactattt aattttctta
    19621 taataatttc atgtatgctt tctggatttt tataagtaga atcttcagtc aaatcttcat
    19681 ccgaattttc aaaggtattt ttatttaaat tctttttatt taaattattt tttaataatt
    19741 cttttttctt tgtctcattt tctgtttcat acccagtatg aattatcaaa tcataatctt
    19801 tgtctatact ctcttgattt atacggctgt ataggttggt attactgttc ttaaacaact
    19861 catctctatg tttatatttc attgtttttt ggttattgtt aatagttgca tcaatgtatt
    19921 tctctatatt tttgaaaata tcaccattct ttgttacaat ttctgcatta ctactttcag
    19981 aacaaacata actatataca gaacaacaat ttccctttac tcccctactt attaatctca
    20041 atatacctaa atctataaat tcatttacaa gtctacttat tgtagatata gatacatcaa
    20101 ggtcagatgc agctttcctt actgtcatca taaattgtcc tcttggcaga gttcctttta
    20161 atctttgtat attttctttt ctcattacat agtgattaaa ccttattcta tttacatctc
    20221 ttttttcatt aaaatataat actgctgaat ttaattgata aaaactatta ctcatattcc
    20281 cactcctcca atttaaatag ataatttgtt gtaaagtttt tagatttttt aataacttat
    20341 taaatgatta tttttattaa aaagtattct ttgatatttt cattttaaag
//
LOCUS       DAEORM030000064        19842 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.064, whole genome shotgun sequence.
ACCESSION   DAEORM030000064 DAEORM030000000
VERSION     DAEORM030000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 19842)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19842)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 19842)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19842
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.064"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            complement(<1..272)
                     /locus_tag="KRH23_003122"
     CDS             complement(<1..272)
                     /locus_tag="KRH23_003122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004061 - arylformamidase activity
                     [Evidence IEA];
                     GO_process: GO:0019441 - L-tryptophan catabolic process to
                     kynurenine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cyclase family protein"
                     /protein_id="HHS5226399.1"
                     /translation="MKVFDLTHVTHNDMPVYAEPNRPDIKKVAIIEENGYQETLISVF
                     SHNGTHMDSPRHMYTKGETLDKLDIENFVGKAYVLELEKGNENIEL"
     gene            complement(362..1441)
                     /locus_tag="KRH23_003123"
     CDS             complement(362..1441)
                     /locus_tag="KRH23_003123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIR2 family protein"
                     /protein_id="HHS5226400.1"
                     /translation="MKIAIFLGAGASAAENLPIQNELFSEYFKKLNPTNYNTKMNREL
                     YIFFKQMFNIDIVKDNIDNANFPTFEEVLGLLDLAEQRKEAFRNFGLENLNNRSDSIR
                     FLRQYLILLMAEAIHNTPRTDNKYHKLLVENLLENDLLLDTTFISANYDIHIDNTVTG
                     LRDKNDLPIMLDYGVEFTNFKEELNWRKPKEPLIKLYKIHGSLNWLYCPICNSVTLTP
                     HEGGVMKLIENSSETKCLECGELTEPIIVPPTYFKNMSNIFLSNVWNETEKTLRDTDL
                     LIFCGYSFPEADMHIKYMLKRVQTNRKKPPLKIMVFNNHSQKQRITLKKEEGRYKRFL
                     GEDVIFTDNSFQDFSVNPLRFIKNI"
     gene            complement(1574..2920)
                     /gene="pepV"
                     /locus_tag="KRH23_003124"
     CDS             complement(1574..2920)
                     /gene="pepV"
                     /locus_tag="KRH23_003124"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0016805 - dipeptidase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HHS5226401.1"
                     /translation="MKEQIKEKVNSLQDEMISSIQESVKIPSVISEATENCPFGENVD
                     KALRGILDLCKSLGFKTVYKDGYYGYAEIGQGEKMIGILGHVDVVPEGDLESWNYPPF
                     EAVLEDGKLYGRGTQDDKGPTISAIYAVKALMDLNVDFNKRIRFIFGADEENLWRCIN
                     KYKENNEEIPNYGFTPDSRFPITNAEKGLLQVHLTCDSKSDIELSVGKALNAVPGKAI
                     YIGKYSDKLKKELDKLNFEYTVEGNKICIIGKSVHSAASDTGINAVARLCIALNNIGI
                     DSNIIKFLAEVIGEDANGNNIIPNCKDDVSGKLTVNIGRVTIDNEKEFAGIDVRIPVT
                     YKKDDFVKELKKMTDKYNLNYEEYDFLDSIYVPEDTLLVKTLRKVYEEETGLDGTPLS
                     SGGATYARALDNCVAFGAIFPGKPETEHQANEYLIVEDIIKATQIYALSIYELLKI"
     gene            complement(2989..4269)
                     /locus_tag="KRH23_003125"
     CDS             complement(2989..4269)
                     /locus_tag="KRH23_003125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HHS5226402.1"
                     /translation="MLNETKELLKDYYGIDDDTFKLSQEIMEEIKDKFEEIKEIREYN
                     QYKVLKAMQESKLSDMHFNWTTGYGYNDIGREKIEEIYSKVFNTEDALVRPIIVNGTH
                     ALTLCIQGIVRPGDEILSVTGRPYDTLEGVIGIREEKGSLKEYGVTYDDVDFLEDGNL
                     DLEGIKNKINDRTKLVMIQRSKGYSWRKSLSISDIKEAIEVIKSVKPEAIVMVDNCYG
                     EFLDTKEPTDVGADVMAGSLIKNPGGGLALTGGYIAGRKDLIELISYRMTSPGIGKEC
                     GLTFGTTRNVLQGFFLAPYIVSQAVMGAIFCSRAFEKLGYDVLPKYDDLRSDIIQCIR
                     LNNADEVISFCEGIQEAAPVDSYVKPVPWDMPGYESEVIMAAGAFIQGSSIELSADAP
                     IRPPYNVYFQGGLTFDHSKMGTLKAIEFIKKLKK"
     gene            complement(4396..4656)
                     /gene="hfq"
                     /locus_tag="KRH23_003126"
     CDS             complement(4396..4656)
                     /gene="hfq"
                     /locus_tag="KRH23_003126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA chaperone Hfq"
                     /protein_id="HHS5226403.1"
                     /translation="MKNTVLNLQDLFLNNARKERIPVTIYLVNGVQVKGLVKGFDSYI
                     ILIEGDNRQQNMIYKHAVSTIQPGKYINLTNQNQNNNNNNNR"
     gene            complement(4770..5705)
                     /gene="miaA"
                     /locus_tag="KRH23_003127"
     CDS             complement(4770..5705)
                     /gene="miaA"
                     /locus_tag="KRH23_003127"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0052381 - tRNA dimethylallyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HHS5226404.1"
                     /translation="MKKIPLIILTGPTAVGKTDLSIKLAKDMNAEIISADSMQIYEYM
                     DIGSAKVTEEEMQGVKHYLIDEVKPDYPFSVSEFQQRAKKYIHEINEKEKCVLVTGGT
                     GLYLNSLIYNMDFAQSDANNELREELQKQLAEKGIDYMHNKLKELDEESANRIHKNNT
                     KRVIRALEVCLSGKKMNDFSSDLKFNEEYQPIIIVLNRDREHLYQRINMRVDIMLKNG
                     LVEEVKKLLSMGFKKDMISMQGIGYKEILKYLDGEYTYEEAIEIIKRDSRRYAKRQIT
                     WFKRYKTAKWFDLDQYENIDELKNEIILYIKDSIK"
     gene            complement(5743..7710)
                     /gene="mutL"
                     /locus_tag="KRH23_003128"
     CDS             complement(5743..7710)
                     /gene="mutL"
                     /locus_tag="KRH23_003128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HHS5226405.1"
                     /translation="MKNIINILDDLTINKIAAGEVVERPSSVVKELIENSIDAGANKI
                     SIDIIDGGKSLIKITDNGIGIPSSEVEKSFLRHATSKIKKIDDLYDLYSLGFRGEALA
                     SISAVSKLEMTTKTKDEIIGTKIYVEGGKIISKEPIGSTNGTTIIIKDIFFNTPARQK
                     FLKSTHAETINISDLINKLAIGNPNIQFKYTNNNKQMLNTPGDGKLVNTIRSIYGKEI
                     TENIIDVEFKCNHFKMNGYIGNNNIYRSNKNLQHIYINKRFVKSKIIIDAITESYKSI
                     IPIGKHAVCFLNIEVDPSCIDVNIHPNKLEIKFEKEQEVYIELRDFLKVKLIHSNLIG
                     KYATYSDKKTQPRIAINSREKSTDYKLRNNDLLESTPKNSNITKGKDEVIEVVTLSSE
                     KPINEFQSVSEVLNASVEDDVKNINYLSEDSANDNIQEEFQVDGIKNEGNYYLGDSIK
                     DSEEEYLCSSKRKFSLYGYSVIGVVFNTYIILSKDDSMYLLDQHAAHERILYERYMEK
                     FYRQDINMQILLDPVVIEVSNVDMLQIENNLELFMKFGFELEIFGNNHIMVRCVPTIF
                     GVPETEKFILQIIDNIEEITSNYDLKGERFASMACRSAIKANDKIYDIEIKSLLEQLE
                     KCENPFTCPHGRPIMVEISKTEIEKMFKRIM"
     gene            complement(7721..10564)
                     /gene="mutS"
                     /locus_tag="KRH23_003129"
     CDS             complement(7721..10564)
                     /gene="mutS"
                     /locus_tag="KRH23_003129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HHS5226406.1"
                     /translation="MQIDMNKLTPMMKQYLEVKNRYKDCILFFRLGDFYEMFFEDALV
                     ASKALEIALTGKACGLEERAPMCGVPFHSANSYISKLVENGYKVAIGEQMEDPSTAKG
                     IVRREVIRVITPGTVLDGNLLENKKNNYLLSLYKDGTNIGLTYVDISTGETNATCLNE
                     DKVIEEIAKIHPTEIIINDLDFIEKLRDIATVSNIYINESFSDNYLDINILKEYFPDV
                     YLQKLKFDDKGLIKSSLSILLNYIYNTQKQITSNINNINIYNSSEYMVLDMFTRTNLE
                     LTQTIRGNKKKGSLLHVLDKTSTAMGGRLLRKYVEEPLINKSKIENRLDVIEEIKDDF
                     ILREDLNDILKNIYDIERICGKIAFERVTPKELIHLKNSIEKLPNLKDTINLSNAKIL
                     KEYVSEMDKLDDIYNLIDEAILEEPTITIKDGNIIKSDFSDELKELREISKNGAFLVK
                     EIENREREKTGVKSLKIGFNKVFGYYIEITKANFKQAKLDETYIRKQTLSNAERYITP
                     ELKEIEEKILHAEEKIKSLEYEIFVEIRDTIYKNIDRIQKVAKTIANIDVFVSLATVA
                     HINNYVKPAINENNKLDIRNGRHPVVENIVGEENFVPNDTYLNRGENIINIITGPNMS
                     GKSTYMRQTAIIALMAHIGSFVPAESADIPILDRIFTRVGASDDLSQGQSTFMVEMNE
                     VSLILKNATERSLVILDEIGRGTSTYDGISLAWSIVEYIQKNIRCKTLFATHYHELTD
                     LEEEFKEVKNYSIAVKEDGEGIIFLRKIIPQGADKSYGIYVAKLAKLPDEVIERAKYI
                     LKDLEKNHVYNSVAINGDKENNNIINSNLDEELVKVNQSNFKNKYESLKIEHELIVKD
                     YKHIKKDYDKLNSKFKALNDEVALMKQNDDKEKINQEDSVKEVALTQISFDSVNRDIL
                     SEEILNLDILNMTPLDAINSLYNLQRKAKEIKS"
     gene            complement(10727..11461)
                     /locus_tag="KRH23_003130"
     CDS             complement(10727..11461)
                     /locus_tag="KRH23_003130"
                     /EC_number="7.6.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHS5226407.1"
                     /translation="MLTQMNFYHNKKVKVSIENVSKTYKDIEVLKDISIDVYEGEFVS
                     ILGPSGCGKSTIFNIITKLTDYDSGKVNINGKYSYMYQKDLLLPYKTIIDNVSLPLIL
                     KKEKKSKARSMVKPYFEVFGLSGYEDKYPSELSGGMRQRANFLRTFINSNDIMLLDEP
                     FGALDSLTKTSMQKWLLDVKKKVNSTILLITHDIDEAIMLSNRIYVISKKPSIVKKEF
                     VIDSRKLNEDNLENIIKLKKEIISLL"
     gene            complement(11430..12443)
                     /locus_tag="KRH23_003131"
     CDS             complement(11430..12443)
                     /locus_tag="KRH23_003131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HHS5226408.1"
                     /translation="MNFKKLGILGLVSVFTLTTITGCSSNNNKDKNNDKDTSSKKVTM
                     VLDWTPNTNHTGLFVALDKGYYKEEGLDVEIVQPPESGAETLVATGKADFGISYQEQV
                     TYAKTSEDPLPIKAVATVIQHNTSGFASPKEKNITTAKDFEGKTYGGWGSPSEEAVFK
                     AVMKKNGADFNKLKIVNTGQDDFFAAMKTVDFAWIFEGWDAVKADLIGYDLNFIPVKD
                     LDERLDYYTPLIISNETVLKDNPELAKKFLKATTKGYEYAIKNPEESAKILVKHAPEV
                     DEKLALKSQEYLASKYKDDAPRWGEMKDSVWNNYTSFLKEYKLIDKDMKASDAYTNEF
                     LPQ"
     gene            complement(12465..13235)
                     /locus_tag="KRH23_003132"
     CDS             complement(12465..13235)
                     /locus_tag="KRH23_003132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHS5226409.1"
                     /translation="MKNLEIIDKVKDSIYPIATFLFILILWQSMVGVLEVPQYILPTP
                     VDIINVFFKDYQNLSMHAVVTIGEAILGFIVAIIISLVIGILMDFVSIIKKCLYPIML
                     VTQMIPTIIIAPLFMIWFGFGTMPKVLMVMLTCFFPILISFVDGIENIDKDYLNLFKT
                     MDSNKVNTFIHLKFPMAMDKFFSGLKISATYAVMAATVAEWLGGTKGLGVYMLRSKSA
                     YALDKVFASTILVVIFSLMFVGIVQAVKKVVIRHRLID"
     gene            complement(13210..13500)
                     /locus_tag="KRH23_003133"
     CDS             complement(13210..13500)
                     /locus_tag="KRH23_003133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MTH1187 family thiamine-binding protein"
                     /protein_id="HHS5226410.1"
                     /translation="MVIADIAVMPLRPYKGEEEMYKVVDACIAEIEKSGLKCEIGAMS
                     TTVEGDFDEVFELLKKVHKIPFNLGCERVITVARVDEKAGGLTIDEKLRNHR"
     regulatory      complement(13631..13730)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     regulatory      14350..14439
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            14492..14668
                     /locus_tag="KRH23_003134"
     CDS             14492..14668
                     /locus_tag="KRH23_003134"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226411.1"
                     /translation="MFMDKMDRCTHILTAYICSSRDYCNFIDTQLNDFILEYGENVVE
                     SCLHQVMVLVSRYN"
     gene            complement(14783..15139)
                     /locus_tag="KRH23_003135"
     CDS             complement(14783..15139)
                     /locus_tag="KRH23_003135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HHS5226412.1"
                     /translation="MDIDNNFEEFPNIEERQKDFNCSIGFTMTVIGSKWRAIILWHIL
                     KQKPIRYSQLKKEVVHISHKILSQELKYLEREGLIKRISYPTIPQKVEYLSTKRGKSL
                     ESILLELCNWGKQYMR"
     gene            15469..16308
                     /locus_tag="KRH23_003136"
     CDS             15469..16308
                     /locus_tag="KRH23_003136"
                     /inference="COORDINATES: protein motif:HMM:TIGR00654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family isomerase"
                     /protein_id="HHS5226413.1"
                     /translation="MTNADGLSESQMQKIARELNNSETAFIFNNLAKNHQENYDVHIR
                     FFTPTNEVPICGHATIAAHYVRAVENQFNNKTVFQKTGAGILPVDIIKKDNDYEIIMT
                     QGKIEVSPPLQQTYQKRLLNAFGILKEDIRTDCLIAISSTGHSKVMIGIKELSTLNSL
                     SPNLYELSKISQEIKCNRHYIFTLHNKETLQVHGRMFAPAIGISEDPVTGNANGPLGA
                     YLVHYKVIPTPNTEFIFEAVQGETIKRKGKMLVKVIILDNKPVEVKIIGKAVIAFSTN
                     IEI"
     gene            16539..17150
                     /locus_tag="KRH23_003137"
     CDS             16539..17150
                     /locus_tag="KRH23_003137"
                     /EC_number="3.6.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016817 - hydrolase activity, acting on
                     acid anhydrides [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0009132 - nucleoside diphosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HHS5226414.1"
                     /translation="MINDIKNKFKNYKPYINGYKNMKRASVLIPIVEINNTHYILFEV
                     RSKNLKHQPSEISFPGGKIESGETPYEAVIRETCEELGTFSDNIEVISSLDLLITPVK
                     FIIHPYLGYIKNINNLNINKDEVDHTFLVPIKYLLENPPNTYSNTVKVFPDENLPYGS
                     IPNQKDYKFESGSYPILFYKYKDYVIWGMTAKILENFLNFLSE"
     gene            17448..17786
                     /locus_tag="KRH23_003138"
     CDS             17448..17786
                     /locus_tag="KRH23_003138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3784 domain-containing protein"
                     /protein_id="HHS5226415.1"
                     /translation="MFAVGFVVIIALAFFILSVLLFNGKASMLLAGYNSMSKKEKARY
                     DKKKLCRSSSIVTFIVSIMLFIMAFLGYRIESGQMDEKKMVPFSIIFIIVILSSVFFN
                     ILYSNKKCKK"
     gene            complement(18189..19625)
                     /gene="miaB"
                     /locus_tag="KRH23_003139"
     CDS             complement(18189..19625)
                     /gene="miaB"
                     /locus_tag="KRH23_003139"
                     /EC_number="2.8.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016782 - transferase activity,
                     transferring sulphur-containing groups [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (N6-isopentenyl
                     adenosine(37)-C2)-methylthiotransferase MiaB"
                     /protein_id="HHS5226416.1"
                     /translation="MSKRKQVTIPIEKIQEQDKYIEQIHRQNEEYFNRTGKRKLVFTQ
                     TFGCQMNEHDSEKLCSMLEEMGYQMSMMVEESDLIIYNTCAVRENAELKVYGNLGQLK
                     HLKGKNPDMKIAVCGCMMQQPHVVEELRKKYKHVDLIFGTHNLYKFPQLLTESINSDK
                     MLVDVWDVDGEVIEGLRSNRKFELKAFVNIMYGCNNFCTYCIVPYTRGRERSRTPEDI
                     INEIKELVANGTKEITLLGQNVDSYGKTLENPVSFSELLRKVNDIEGIERVRFMTSHP
                     KDISDEVIYAIRDCDKVCEFLHLPIQCGSSSLLKKMNRHYTKEYYLEIIEKAKKEVPG
                     IAFSTDLMIGFPGETEEDLLDTLDVVEKVRYDSAFTFIYSKRQGTPAAKMENQIPEDI
                     KHDRFNRVLEAVNRISAEINDGYKDRIVEVLVEGRSKNNENKFAGRTRQNKLVNFEGG
                     NDDLIGKLVMVKITEPRTFSLNGILVNN"
BASE COUNT         6463 a         3235 c         2142 g         8002 t
ORIGIN      
        1 tctaattcta tattctcatt tcccttttca agttctaata cataagcttt cccaacaaaa
       61 ttttctatat ccaacttatc tagggtctca cctttagtat acatatgtct tggtgaatcc
      121 atatgagttc cattgtgaga aaatacacta attaatgttt cttgataacc attttcttca
      181 ataatagcta ctttcttgat atctggtcta ttaggctctg catatacagg catgtcatta
      241 tgtgtcacat gagttaaatc aaaaaccttc atctttatat accccctatg tttttatttt
      301 ctattatata cctaaattca ttttatttct atcagatttt attccattat ataccatact
      361 actatatatt ttttataaac ctcaagggat ttaccgaaaa atcttggaaa gaattatcag
      421 taaatataac atcttcaccc aaaaaacgtt tataccttcc ttcttctttc tttaaagtaa
      481 ttctctgttt ttgtgaatga ttattaaaaa ccattatctt aagaggaggt ttttttctat
      541 tagtctgcac tctttttaac atgtatttta tgtgcatatc agcttcagga aatgaatatc
      601 cacaaaatat taaaaggtca gtatctctta aagttttttc tgtttcattc caaacattac
      661 ttaaaaatat gtttgacata ttcttaaaat atgttggtgg cactataata ggttctgtta
      721 actcaccaca ctctaaacat tttgtctctg aactattttc aataagcttc atgacaccac
      781 cttcatgtgg tgtaagagtt acactattac aaatggggca ataaagccaa ttcaatgacc
      841 catgtatctt atataatttg attaatggtt cttttggttt tctccaattt aactcctctt
      901 taaaatttgt aaactccaca ccataatcaa gcataattgg caaatcattc ttatctctta
      961 atccagtaac tgtattgtct atatgtatat cataatttgc actaataaaa gtagtatcaa
     1021 gaagcaaatc attttccaaa agattttcaa ctaaaagttt atgatattta ttatctgttc
     1081 taggtgtatt atgaattgct tcagccatta gcagtattaa atattgtctt aaaaaacgta
     1141 tactatcact tctgttattt agattttcta gtccaaaatt tctaaatgct tcttttcttt
     1201 gttctgctaa gtctaaaaga cctaaaactt cttcaaaggt aggaaaattt gcattatcta
     1261 tattatcttt tactatatca atattgaaca tctgtttaaa gaaaatatac aattctctat
     1321 tcattttggt attataattt gtgggattta gttttttaaa atattcgcta aaaagttcat
     1381 tttgaatagg tagattctct gctgctgaag ctcctgctcc taaaaatatt gctattttca
     1441 tatagttcct cctaatataa atattactcc tatttttata tccattaaat atccatatca
     1501 tttattttat gatacaacaa taaagctgtc ttttactaga aaaaatccta ttacaagaca
     1561 gccttatatt atattaaatc tttaataatt cgtaaataga aagagcatat atttgagtag
     1621 cttttataat atcctctact attaagtatt cattagcttg gtgttctgtt tctggttttc
     1681 ctggaaaaat agctccaaat gcaacacaat tatctaaagc tcttgcgtat gttgctcctc
     1741 cagatgaaag tggtgttcca tcaagaccag tttcttcttc atatactttt ctaagtgtct
     1801 taacaagaag agtatcttct ggaacataga ttgaatccaa gaaatcatat tcttcataat
     1861 ttaaattgta tttatctgtc attttcttta actcttttac aaaatcatcc tttttgtatg
     1921 ttactggaat ccttacatct attcctgcaa attctttttc gttatcaata gttactctac
     1981 ctatatttac tgttagttta cctgatacat catccttgca attaggaatt atattgtttc
     2041 cattagcatc ttcaccaata acttctgcta aaaacttaat tatattagaa tctataccta
     2101 tattattaag agctatacaa agtctagcca ctgcatttat accagtatca cttgctgctg
     2161 aatggacact ttttccaatt atacagattt tattaccttc aacagtatat tcaaaattta
     2221 atttatcaag ttcttttttt aatttatcag agtattttcc aatatagatt gctttacctg
     2281 gaactgcatt taaagccttt ccaactgaca actctatatc acttttgcta tcacaagtca
     2341 aatgaacttg taaaagacct ttctctgcat ttgttattgg gaatctagaa tctggagtaa
     2401 atccatagtt tggtatttct tcattatttt ctttatattt atttatacat ctccaaagat
     2461 tttcttcatc agccccaaaa atgaatctta tcctcttatt aaagtctaca tttaaatcca
     2521 taagagcttt cactgcataa attgctgata ttgtaggtcc tttatcatct tgtgttcctc
     2581 ttccatacaa tttaccatct tctaaaacag cttcaaatgg agggtaattc cagctttcta
     2641 aatcaccttc tggaaccaca tcaacgtgac caagtatacc tatcattttt tcaccttgtc
     2701 ctatttctgc atatccataa tatccatctt tgtatactgt cttaaatcct aaagatttac
     2761 ataagtctaa tatacctctt aaagctttat ctacattttc accaaatggg caattttcag
     2821 ttgcttcaga tataacacta ggtattttta cactttcttg tattgaagaa atcatttcat
     2881 cttgtagaga atttactttt tctttaattt gctctttcat attatcaccc ttcaattttc
     2941 atcataatat actaataaat attttgacct tttaaaaaaa aaatatgctt attttttcag
     3001 tttttttata aattcaatcg cttttaaagt ccccattttt gaatggtcaa atgtaagtcc
     3061 accttgaaaa taaacattat aaggaggtct tattggagca tctgcactta attctataga
     3121 agaaccttgt ataaatgctc ctgctgccat tatgacttca ctttcgtatc caggcatgtc
     3181 ccaaggaaca ggttttacat aagaatcgac tggtgcagct tcttgtatac cttcacaaaa
     3241 acttattact tcatcagcat tattaagtct aatacattga ataatatcac ttcttaagtc
     3301 atcatatttt ggtaatacat catatcctaa tttttcaaaa gctcttgagc aaaagatagc
     3361 tcccattaca gcctgagata ctatataagg cgccaagaaa aaaccctgaa gtacatttct
     3421 agttgttcca aaagtaagac cacattcttt tcctattcca ggagaagtca ttctataaga
     3481 tataagctca atcaaatctt ttctaccagc tatatatcca cctgtcaatg caagcccacc
     3541 accaggattt tttattaaag agccagccat aacatctgct ccaacatcag taggctcttt
     3601 ggtatctaaa aactcaccat aacaattatc aaccattact atagcttctg gtttaacaga
     3661 ctttattact tctatagctt cttttatatc actaattgaa agtgattttc tccaagaata
     3721 tccttttgac ctttgtatca taacgagttt agttctatca tttattttgt ttttaattcc
     3781 ttctaaatct aagtttccat cctctaaaaa atctacatca tcatatgtaa caccatactc
     3841 tttcaatgaa cctttttctt ctcttatgcc tataactccc tctaaagtat catatggtct
     3901 accagtaaca gataaaattt catctcctgg tctaactata ccttgtatac ataaagtaag
     3961 tgcatgtgta ccatttacaa ttattggtct tacaagagca tcttctgtat taaatacttt
     4021 agaataaatt tcctctattt tttcacgacc aatatcatta tatccatatc ctgtagtcca
     4081 gttaaagtgc atatcactta gtttagattc ttgcatagct tttaaaactt tatattgatt
     4141 atattctctt atttctttta tttcttcaaa cttatctttt atttcttcca ttatttcttg
     4201 cgatagttta aaagtatcat catctattcc atagtagtct tttaataatt cttttgtctc
     4261 attaagcatt ttatcacctg tctctttatt attttattta aacatgtaaa ggagactatt
     4321 ttactaaaac aaataaatta tagtttataa gttagtataa gtctcctctc aatcatctta
     4381 aattaaatta attatctatc tgttgttatt attattgttg ttttggtttt gatttgttag
     4441 attaatatac tttccaggtt gtatagttga tacagcatgt ttataaatca tgttttgttg
     4501 tctattatcc ccttctatta atattatata actatcaaac ccctttacaa gccctttaac
     4561 ttgcactcca ttaactaaat atatagtaac aggtatcctt tctttccttg cattatttaa
     4621 aaacaaatct tgtaaattta aaactgtatt tttcattaga tttgtaccct cccaagatta
     4681 aattgaactt ctaaaatatt cctaccttat attctatata agttatgaca aattttcaat
     4741 attaagttgt atacttaaaa atttatatat tattttatag aatctttaat atataagatt
     4801 atttcatttt ttaattcgtc tatattttca tattggtcta aatcaaacca ttttgctgtt
     4861 ttatatcttt taaaccatgt tatctgacgt tttgcatacc ttctagaatc tcttttaatt
     4921 atttcaatag cttcttcgta tgtatattct ccatccagat actttaatat ctctttataa
     4981 cctatacctt gcattgatat catatctttt ttaaatccca tacttaaaag tttttttacc
     5041 tcttcaacca atccattttt aagcataata tcaactctca tatttattct ttgatacaaa
     5101 tgttctctat ctctatttag aactattatt attggttgat attcttcatt aaattttaaa
     5161 tcacttgaaa aatcattcat tttcttacca cttagacaaa cttcaagagc tcttatgacc
     5221 cttttagtat tgtttttatg gattctatta gcagattctt catcaagttc ttttaactta
     5281 ttatgcatgt aatctattcc cttttcagca agctgttttt gaagttcttc tcttaattca
     5341 ttattggcat cagattgtgc aaaatccata ttatatatta aagagtttaa ataaagtcct
     5401 gtgcctccag ttactaaaac acatttttcc ttttcattta tttcatgtat atattttttt
     5461 gctctttgtt gaaactctga aactgaaaat ggatagtcag gcttaacttc atctataagg
     5521 taatgcttca ctccttgcat ctcttcctct gtaacttttg cacttccaat atccatatat
     5581 tcatatattt gcatagaatc agctgaaatt atctctgcat tcatatcttt tgctaatttt
     5641 attgacaaat ctgtttttcc aacagcagtt ggacctgtaa gtattataag tggtattttt
     5701 ttcataacat tcctttccat atattttaaa tatccaaata ttttacataa ttcttttaaa
     5761 cattttttct atttctgtct tagatatttc gaccattata ggtcttccat gaggacatgt
     5821 aaatggattc tcacactttt ctagctgttc caataaactt tttatttcaa tatcgtatat
     5881 tttatcattt gcttttatag cagacctaca tgccatagat gcaaatctct ctccttttaa
     5941 atcataatta cttgtaattt cttctatatt atcaattatt tgaagtataa atttctcagt
     6001 ttcaggtact ccaaatatag taggaacaca tcttaccatt atatgattat tgccaaaaat
     6061 ttctagctca aaaccaaatt tcataaataa ctccaagtta ttttcaattt gaagcatatc
     6121 tacatttgat acttcaataa ccactgggtc taaaagtatt tgcatattta tatcttgtct
     6181 atagaacttc tccatatatc tttcatatag tattctttca tgtgcagcat gttggtccaa
     6241 caaatacata gaatcgtctt tgctcaaaat tatataagta ttaaatacaa ctccaattac
     6301 agaatatcca tataaagaaa acttgcgttt tgaactacac aagtattctt cttcactgtc
     6361 cttaatacta tctcctaagt aataatttcc ttcattttta attccatcaa cttgaaactc
     6421 ttcttgtata ttatcatttg cactatcttc acttagataa ttaatgtttt ttacatcatc
     6481 ttctacactt gcatttagga cttcacttac tgattgaaat tcatttattg gtttttcact
     6541 tgataaagta acaacttcaa tgacttcatc cttaccttta gtaatattac tatttttagg
     6601 agtagattct aataaatcat tatttcttaa tttataatct gtactttttt ctctactgtt
     6661 aatagcgatt ctaggttgtg tttttttatc actataagta gcatattttc caataagatt
     6721 tgagtgtatt aatttaacct ttaaaaaatc tctaagttct atatacactt cttgttcttt
     6781 ttcaaattta atttcaagtt tattggggtg tatatttaca tctatacatg atgggtctac
     6841 ttctatattt aagaagcaca ctgcatgttt acctattgga attatagact tataactttc
     6901 tgttattgca tctatgatta ttttactttt tacaaatctt ttatttatat agatatgttg
     6961 taagttttta tttgaacggt atatattgtt attacctata tatccattca ttttaaagtg
     7021 attgcactta aactctacat ctattatatt ttccgttatt tcttttccat atatacttct
     7081 aatagtgttt acaagttttc catcccctgg agtatttagc atctgtttat tgttatttgt
     7141 atatttaaat tgaatgtttg gattacctat tgcaagttta tttatcaaat cacttatatt
     7201 tatagtttct gcatgagtag attttaaaaa tttctgtctt gctggtgtat taaagaaaat
     7261 atcttttata atgatggtag ttccattagt agaacctatt ggttctttcg atattatttt
     7321 tccaccttca acatatattt tagttcctat tatttcatct ttagttttag tcgtcatttc
     7381 taattttgat acagctgaaa tagatgccaa tgcttctcct ctaaaaccaa gagagtataa
     7441 atcatacaaa tcatcaattt ttttaatttt actagtagca tgtctcaaaa atgatttttc
     7501 aacttcactt gaaggtattc ctattccatt atctgtaatc ttaattagac tttttcctcc
     7561 atcaattata tctatggaaa ttttatttgc acctgcatca atggagtttt caataagttc
     7621 ttttactaca gaagaaggtc tttctacaac ttcacctgct gctatcttat ttatagtcaa
     7681 atcatctagg atgttaatta tatttttcat ttttacacct ctaagatttt atttcttttg
     7741 cttttctttg aagattataa agagagttta tagcatctaa tggagtcata tttaaaatat
     7801 ccagatttaa aatttcttct gatagtatat ctctatttac actatcaaaa gagatttgag
     7861 ttaaggctac ttcttttaca gaatcttctt gattaatttt ctctttatca tcattttgct
     7921 tcattaaagc aacttcatca tttaatgctt taaatttaga atttaattta tcataatcct
     7981 tttttatatg tttgtagtct tttactataa gttcatgttc tatttttaga gattcatatt
     8041 tattcttaaa attactttga tttaccttaa ctaattcttc gtccaaatta ctattaatta
     8101 tattattgtt ttctttatct ccatttattg caacactgtt gtaaacatga tttttttcca
     8161 agtctttaag tatatatttt gctctttcta tgacttcgtc tggtaattta gctaatttag
     8221 caacatatat tccataactc ttgtctgctc cctgaggaat tatttttctt aaaaatatta
     8281 ttccttcccc atcttctttg actgctattg aataattttt aacctcttta aactcttctt
     8341 ctaaatcagt aagttcatga taatgtgttg caaataatgt cttacatcta atattttttt
     8401 gaatatattc cactattgac catgctaaac ttataccatc ataggtacta gttccacgac
     8461 ctatttcatc taatataact aaacttctct ctgttgcatt ttttaatata agggatactt
     8521 cgttcatctc taccataaaa gtagattgac cttgagataa atcgtcacta gctccaactc
     8581 ttgtaaatat tctatctaat attggaatat cagcagactc tgctggtaca aatgagccta
     8641 tatgtgccat aagagctatt atagcagttt gtctcatata tgttgattta cctgacatat
     8701 taggaccagt tattatatta ataatgtttt ctccacgatt taaataagta tcatttggaa
     8761 cgaaattttc ctctcctact atattttcga caacaggatg tctaccattt cttatatcaa
     8821 gtttattatt ttcatttatt gctggtttta catagttatt tatatgtgca actgttgcaa
     8881 gggacacaaa aacatctata ttagctatag tcttagccac tttttgtatt ctatctatgt
     8941 ttttatatat tgtatctctt atctctacaa atatctcgta ttctaaagat ttaatctttt
     9001 cctctgcatg tagtatcttt tcttctattt cctttaattc tggagttata tatctttctg
     9061 cattactaag tgtttgcttt cttatatatg tctcatctag ctttgcctgt ttaaagttgg
     9121 cttttgttat ttctatataa tatccaaaaa ctttattaaa gcctattttt aatgatttaa
     9181 ctcctgtttt ttctctttcc ctgttttcta tttcctttac aagaaaggct ccattcttag
     9241 aaatctctct tagttcctta agttcatcac taaaatctga tttaattatg tttccatctt
     9301 ttatggttat cgtaggttct tctagaatag cttcatctat taaattgtat atatcatcta
     9361 atttatccat ttctgaaaca tactctttta ggatttttgc atttgataaa tttatagtat
     9421 cttttaaatt aggtaacttt tctatcgaat tttttaagtg aattaactct tttggtgtta
     9481 ctctctcaaa tgctatcttt ccacatattc tttctatatc gtatatattt ttaagtatat
     9541 catttaggtc ttctcttaat ataaagtcat cttttatttc ttctattaca tctaatctat
     9601 tttcaatttt agatttattt atcaaaggtt cttctacata ttttcttaaa agtctacctc
     9661 ccattgctgt agaagtttta tcaagtacgt gtaataatga accttttttc ttattccctc
     9721 ttatagtttg agtaagttct aaattagttc tagtaaacat atctagaacc atatattctg
     9781 atgaattgta tatatttata ttattaatgt tagatgttat ttgtttttga gtattgtata
     9841 tataattcag aagaattgat aagcttgact ttattagacc tttatcatca aactttagtt
     9901 tttgtagata aacatctgga aaatattctt ttaatatatt tatatccaaa tagttatcac
     9961 taaaactttc atttatgtat atattactta cagtagctat atctctaagc ttttctataa
    10021 agtctaaatc atttataatt atttcagttg gatggatttt tgcaatttct tcaattacct
    10081 tatcttcatt taaacatgtt gcattagttt ctcctgtact tatatcaaca taagttagac
    10141 ctatattagt accatcctta tacaaagata ataaataatt attcttttta ttttcaagta
    10201 aatttccatc taaaactgta ccaggagtga tgactcttat aacctctctt ctaacaattc
    10261 cttttgctgt agatgggtct tccatttgtt cacctattgc tactttatat ccattttcaa
    10321 ctaattttga tatatatgaa ttggctgagt ggaaaggaac accacacata ggagcacgtt
    10381 cttctaaacc acaagctttt cctgtcaatg ctatttcaag agcttttgaa gctactaatg
    10441 catcttcaaa aaacatttca taaaaatctc caagtctaaa aaacagtata cagtctttat
    10501 atctattttt tacttcaaga tactgtttca tcataggagt taatttattc atatctattt
    10561 gcattatcaa acctccttct tttctaatta aatattatat catagtagat gattattatt
    10621 aacacaatat ataaaatttt gacatataac taaaaacaat ccaaaatgta tactcacatt
    10681 ttggattgct aagtttaatg cttattaaat aaaaatatat atttttttac aataaagata
    10741 ttatttcttt tttaagttta atgatatttt caaggttatc ttcatttaac tttctactat
    10801 ctataacaaa ttctttcttt actattgatg gtttttttga aataacataa attctgtttg
    10861 atagcattat agcttcgtca atatcatgag ttataagaag tattgttgaa tttacttttt
    10921 tcttaacatc taaaagccat ttttgcatgg atgttttagt taatgaatca agtgccccaa
    10981 aaggctcatc taaaagcatt atgtcattag aatttataaa agttctcaag aagttagctc
    11041 tctgtctcat tcctccagaa agttctgaag gatatttatc ttcatatccg cttaatccaa
    11101 acacctcaaa ataaggtttt accattgacc tagctttact ctttttttct ttttttaaaa
    11161 ttagtggtag tgacacatta tctattatag ttttatatgg caagagtaaa tctttttgat
    11221 acatataact atacttacca tttatattca ctttgccact atcataatct gtaagtttag
    11281 ttataatatt aaaaatagta ctttttccac atccacttgg ccctaatata gaaacaaact
    11341 caccttcata aacatcaata cttatatctt ttaaaacttc aatatcttta taagtttttg
    11401 atacattttc tatagatact tttacttttt tattgtggta aaaattcatt tgtgtaagca
    11461 tcacttgcct tcatatcctt atctattaat ttatattctt ttaagaatga tgtatagttg
    11521 ttccatacac tatctttcat ttctccccat cgtggtgcat catctttgta cttgcttgct
    11581 aaatattctt gactctttaa agctagtttt tcatctactt caggtgcatg ttttactaaa
    11641 atttttgctg attcttctgg attttttatt gcatattcat aaccttttgt tgtagctttt
    11701 aagaattttt tagcaagctc tggattatct ttaagcacag tttcattaga aattataagt
    11761 ggtgtataat aatccaatct ctcatctaaa tcttttactg gtataaagtt taagtcatat
    11821 ccaattaaat cagctttaac tgcatcccaa ccttcaaata tccatgcaaa atctacagtt
    11881 ttcatagctg caaagaaatc atcttgacca gtattaacta tctttaactt attaaaatca
    11941 gctccatttt tcttcataac tgctttaaaa acagcttctt ctgatggaga gccccaacca
    12001 ccataagttt ttccttcaaa atctttagct gttgttatat tcttttcttt tggtgatgca
    12061 aacccagaag tattatgttg tataacagtt gctacagctt ttattggaag tggatcttca
    12121 ctagtctttg cataagtaac ttgttcttga tagcttatac caaagtcagc ttttcctgtt
    12181 gctactaaag tttctgctcc actttcaggt ggttgtacta tttcaacatc caaaccttct
    12241 tctttatagt aacccttatc aagtgctaca aataatccag tatgatttgt atttggtgtc
    12301 caatcaagca ccatagttac ttttttagaa gaagtatctt tatcattgtt tttatcttta
    12361 ttgttatttg aagaacatcc agttattgtt gtcaatgtaa aaacacttac taaacctaat
    12421 attcctaact ttttaaaatt cataattgcc tccctcaaat acctttaatc tattaatcta
    12481 tgtcttataa caactttttt tacagcctgt acaattccta caaacattaa actaaatata
    12541 actactaata tagtagatgc aaatacttta tcaagtgcat atgcactttt tgacctaagc
    12601 atataaacac caagtccttt cgttccacct agccattctg caacagttgc tgccattaca
    12661 gcatacgttg cagatatttt aagtccagaa aaaaatttat ccattgccat aggaaattta
    12721 aggtgaatga atgtattaac tttatttgag tccatagtct taaataaatt taaataatct
    12781 ttatcaatat tctcaatgcc atctacaaaa cttattaata taggaaaaaa acaagtaagc
    12841 attaccatca atacttttgg cattgttcca aatccaaacc atatcataaa gagtggtgct
    12901 ataattattg taggtatcat ctgtgtaacc aacataatag gataaagaca tttttttatt
    12961 attgatacaa aatccatcaa tattccaatt accaatgata ttataattgc gactataaaa
    13021 ccaagtattg cttctcctat agtaaccaca gcatgcatgg ataaattttg ataatcttta
    13081 aaaaacacat taattatatc tactggtgtg ggtagtatat actgaggaac ttctaaaact
    13141 cctaccatag attgccaaag aataagtata aacaaaaatg ttgctattgg atatatacta
    13201 tctttgactt tatctatgat ttctaagttt ttcatctata gtcagacctc cagctttttc
    13261 atctactcta gctaccgtta tgactctttc acatccaaga ttaaaaggga ttttatgtac
    13321 cttttttaat aattcaaaaa cttcatcaaa atcaccttca acagtagtgc tcattgctcc
    13381 tatttcacat ttaagaccac ttttttcaat ttcagcaata caagcatcta ctactttata
    13441 catctcttct tcacctttgt aaggtcttag tggcattact gctatgtctg cgattaccat
    13501 ttaaatcact cctttaaaaa taattaatac ctactaggta tattttgttt tttattaaaa
    13561 aattttatta ctaaaaagat attatattta aataaaagaa aagtcttatc caaaatagga
    13621 taagacttat ttttatctta actggtctcc ctacactggc attatccaaa caggttcaaa
    13681 gggtcgagat aaaatctcct ctcagcacat tagctccccg aaatatatta tatcttttct
    13741 acttgattat actacactta tcatatttta acaaattttt tatttatatt agatatttta
    13801 tccgttcaaa aatatctaat ataaattgta cattattaca ccaaataaat tatcttaaaa
    13861 tggtaattta tcaacatctt ccaaaactag attaactgaa ttttctagtt tttattttgc
    13921 tatttcaagc atatttggat gtatatcaat tccatacaaa tattgtgcta aatttctgtt
    13981 ttcactaatc taatttgcaa tcgttacaga ttacagatta gaaatagctt ttagactcta
    14041 cttatcttta tctacaaaaa atctttcaat aaattcagta ataatattca gtaatctaaa
    14101 aataaacctc tatctagatt tttaagatac aagcctttta ataagtacct tttgtgataa
    14161 tataaaaatt actcgtcatt atcatcaaaa tcctcagcaa ccaacatttt agataagaat
    14221 caaactctat aatataatta ttttatccaa tttatttttg agaaataaaa tattttttta
    14281 atttttaaat tttttaatat gcaccttgaa aaaagaaacg ttttcctata ttatggtaat
    14341 agtagaataa aactaaatag gcaaaactag agaaatttag tgacgcaaag ctatagggac
    14401 taagacttat gaaatgagtt atgtcagcca gttgccaaag agatattttc tttttgtttt
    14461 tatgaatgtt ttttaggggg atatatgata tatgtttatg gataaaatgg atagatgtac
    14521 acatatacta actgcatata tatgcagttc acgcgattac tgcaatttta tagatacaca
    14581 attaaatgat tttatactag aatatggaga gaatgtggta gaatcttgtt tgcatcaagt
    14641 gatggtattg gtaagcagat ataattaaag aaattttatt ttctagaaaa ccctttttag
    14701 ttttatctac gttttataat tcattaaaga actaattaaa ataagcttca ttatatattt
    14761 ttcataaagt aaacagttga gtttatctca tatactgttt accccaatta cataattcta
    14821 ataatataga ttctaatgat ttaccacgtt tagtagacaa atattcaact ttttgaggaa
    14881 tagtcggata agaaattctc ttaataagtc cttctctttc aagatacttt aattcttgtg
    14941 acagtatctt atgacttata tgaacaactt ctttttttaa ttgactgtaa cgtattggct
    15001 tttgttttaa aatatgccat aaaataattg ccctccattt acttcctatt acagtcatgg
    15061 taaaaccaat tgaacaatta aaatcttttt gtctttcttc aatatttgga aattcttcaa
    15121 aattattatc tatatccatc tcaatcctct ctttcaaaat agtaagtatc taactaaaaa
    15181 gtgcattctt gtttagcgta ctaattcgta atataatctt aattgtagca tagagcctta
    15241 cataatacta cttttttaga tgtatatgtt taaattttaa tatagacata tgttatttta
    15301 ttaattttat ttaaacagat aataataaat aataatttat ctcaagtttt ctatgtagat
    15361 aaactaatct aatgtttaga aaggattata taatatgaat aaaaaatttc gtctttatca
    15421 agttgactca ttacaaaaga aaaatttaca ggtaatccag ctggtgtaat tacaaatgct
    15481 gatggcttat ctgaatcaca aatgcaaaaa atagcaagag aattaaataa ttcagaaact
    15541 gcttttattt tcaataactt ggctaaaaat catcaagaaa attatgatgt acatatcaga
    15601 ttttttacac caactaatga ggttcctata tgtggtcatg ctactattgc tgcccattat
    15661 gttagagcag tagaaaacca attcaacaac aaaacagtat ttcaaaaaac tggtgctgga
    15721 atattaccag ttgatattat aaaaaaagat aatgattatg aaataattat gacacaagga
    15781 aaaattgaag tatctccacc attacaacaa acctatcaaa aaagattact taatgcattt
    15841 ggtattttaa aggaagatat tcgtacagat tgtcttattg ccatatcatc tacaggacat
    15901 tcaaaagtta tgattggaat aaaggaatta tcaacattaa atagtttatc tccaaattta
    15961 tatgaattat cgaaaataag tcaagaaata aaatgtaata ggcattatat ttttacatta
    16021 cataataaag aaactctaca agttcatgga agaatgtttg ctcctgcaat tggtatttca
    16081 gaagaccctg ttacaggaaa tgctaatgga cccttaggtg cgtaccttgt acattataaa
    16141 gtaataccta cacccaacac agagtttata tttgaagcag ttcaaggaga aacaataaaa
    16201 cgcaaaggca agatgttagt aaaagtaatt attttagata ataaaccagt tgaagtaaaa
    16261 ataattggaa aagctgtaat tgcattctca acaaacatag aaatctaatt atagattcct
    16321 tctaagtaaa tttttgaact ttttaatact aatttaataa caaactaatt tatatacaat
    16381 caaattaatt tttttattat ttgttaatat atatttatca ttatattata taataatata
    16441 gatagttact atatcttata attagataaa tcataattat atattattgt taaaactcaa
    16501 ttatataatt tttaataata ttattttagg aggtaaaaat gataaacgat attaaaaata
    16561 aattcaaaaa ttacaaacca tatataaatg gatacaagaa tatgaagaga gcatctgttt
    16621 taattccaat agtagaaata aataacacac actatatatt atttgaagtt cgctcaaaaa
    16681 atttgaagca tcaacctagc gaaatttctt ttccaggtgg taaaatagaa tcaggtgaga
    16741 ctccatatga agctgttatt agagaaactt gtgaggaact tggaactttt agtgacaata
    16801 tagaagtaat atcaagtctt gacctcctta taacaccagt aaagtttatc atacatccat
    16861 acttaggata tataaaaaat attaataatt taaatataaa caaggatgaa gttgaccata
    16921 cttttttggt tcctataaaa tatcttttag agaatcctcc aaatacttat agtaatactg
    16981 taaaagtttt tccagatgaa aatctaccat atggttcaat tccaaaccaa aaagattata
    17041 aatttgaaag tggaagttat cctattctgt tttataaata taaagattat gtaatttggg
    17101 gaatgacagc aaaaatacta gaaaactttt taaatttttt atcagaataa cactcataat
    17161 aaatcatcaa aacttttaca taagaaattt ataaaagttt ctaaatttaa caattctaaa
    17221 atatcaataa ctatattttg tagcactttt ttattttatt attgtttgaa tatttgatgg
    17281 ttttcaatgc aatttcaaca taaatactat gtattagtgt atactgttga tgaattaaag
    17341 tatgataatc tatttaataa agtatgaagt aaatgatttt aatgtgtctt tatggtaaaa
    17401 ttactaataa gtaataaaat taattaaaat atatggaggt gcttataatg tttgctgtag
    17461 gatttgttgt tataattgca cttgcctttt tcattttaag tgtactatta tttaatggaa
    17521 aagccagtat gctactagca ggttataact ctatgagtaa gaaagaaaaa gcacgatacg
    17581 ataaaaaaaa attatgtaga agttctagca ttgttacttt tattgtctct ataatgctat
    17641 ttattatggc gtttttggga tatagaatag agagtggtca aatggacgaa aaaaaaatgg
    17701 ttcccttttc tataatattt ataatagtca tactttccag tgtatttttt aatatcctct
    17761 actctaacaa aaaatgtaaa aaataaatag ttgtaagttg agcagttaat tataaaatat
    17821 tgactgcttt ttcatattga ctactcttat taaatatttt aatatttaat aatctatgta
    17881 aaaataatga atatagtaca aacttctaat aatgatttta cctttgtggt tacagtccac
    17941 tatatataat ttaatatgat aacagggaat tactaatgac aactaagcaa acttttataa
    18001 aatataataa aacaaaaata gatgtacaat gaaattatat cttatatcaa atttattttt
    18061 attaatagca aaaacttaca ttagcataac atatgacaaa ttcgcttaaa ataaaaattt
    18121 ttaatataat ttgttctata gtacatctat tttgattagt ttacataatt ttattatttt
    18181 gtacaatatt aattatttac taatatccca tttaatgaaa aagttctagg ttcagtaatt
    18241 ttgaccataa ctaatttacc aattaaatca tcatttccac cttcgaaatt tacgagttta
    18301 ttttgtctag ttctaccagc aaacttattt tcattatttt tacttcttcc ttcaactaga
    18361 acttcaacta ttctatcttt atatccatca tttatttctg cagaaatcct atttacagct
    18421 tctaacaccc tattaaatct atcatgcttt atatcttctg gtatttgatt ttccatttta
    18481 gcagcaggag ttccctgtct tttagaataa ataaatgtaa aagctgaatc atatctaact
    18541 ttttcaacca catctaaagt gtccaataaa tcttcttctg tttctcctgg gaaaccaatc
    18601 attaagtctg tagaaaaagc aatacctgga acttcctttt tagctttttc tattatttct
    18661 aaataatatt cctttgtata atgtctattc atttttttca aaaggctact gcttccacat
    18721 tgtattggta gatgtaaaaa ctcacatacc ttatcacaat ctctaattgc gtatattact
    18781 tcatcagata tatcttttgg atgagatgtc ataaatcgaa ccctttcaat tccttctata
    18841 tcattcactt ttcttaaaag ttctgagaat gaaactggat tttcaagtgt cttaccataa
    18901 gaatctacat tttgtccaag taaagtgatt tctttcgttc catttgcaac aagctctttt
    18961 atctcgttaa ttatatcttc aggagttcta cttctttctc ttcctcttgt gtatgggact
    19021 atacaatatg tgcagaaatt attgcatcca tacattatat ttacaaatgc ttttaattca
    19081 aattttctat tacttctaag accttctatt acttctccat ccacatccca tacatccact
    19141 aacattttgt cagaatttat tgattctgta agtaattgcg gaaatttata tagattatgt
    19201 gttccaaata taaggtctac atgtttatat ttttttctta attcctctac aacatgtggt
    19261 tgttgcatca tacatccaca tacagctatt ttcatatctg gattttttcc ttttagatgt
    19321 tttaattgtc ctaagttacc atatactttt agctctgcat tttctctaac tgcacaggtg
    19381 ttatatatta ttaaatcact ttcttcaacc atcattgaca tttggtatcc catctcttct
    19441 aacattgaac ataatttttc tgaatcatgt tcattcattt gacacccgaa ggtttgagta
    19501 aacacgagtt ttctctttcc agttctgttg aagtattctt cattttgtct gtgtatttgt
    19561 tctatatatt tatcttgttc ttgtattttc tctataggta ttgttacttg ttttcttttg
    19621 ctcacgtcta ttcctcctag ttaatttctt atattacaca taaccttaat tatatcaaat
    19681 aagaaaaatc ttttaaagat attattattt ttctagttgt gttttaatag taaatctaat
    19741 gatttatata tactatattt ctaaaatata aaatcatata attattataa taataaaaag
    19801 atgttttaaa ttaaaactta aaacatcttt ccttaaataa aa
//
LOCUS       DAEORM030000065        19787 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.065, whole genome shotgun sequence.
ACCESSION   DAEORM030000065 DAEORM030000000
VERSION     DAEORM030000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 19787)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19787)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 19787)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19787
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.065"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            277..1284
                     /gene="asrA"
                     /locus_tag="KRH23_003140"
     CDS             277..1284
                     /gene="asrA"
                     /locus_tag="KRH23_003140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0016002 - sulfite reductase activity
                     [Evidence IEA];
                     GO_process: GO:0006790 - sulfur compound metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic sulfite reductase subunit AsrA"
                     /protein_id="HHS5226417.1"
                     /translation="MKLKLDSSKFNEGLNYLKKDYKIFAPVLIPFKGTFSDTDVIRYK
                     EVNAFEEMEFAKKANFSPKEVVLPINQVLFYFTEKKFKESDLDNKKILIFLRACDING
                     IKRLDEIYLNNGEEKDYFYKNIRDKVKFALVGCKESFRNCFCVSMDSNKTDNYSIGLN
                     IEGDTLYLDIKDSEFEVFNGEATEFNVDYVTDNLISVDVPENIDSNEMIGNSIWDEYD
                     TRCIGCGRCNFVCPTCSCFTMQDIFYKENENVGERRRVWASCQVDGYTDIAGGNSFRK
                     KQGERMRFKTMHKIHDFKKRFGYHMCVGCGRCDDACPQYISFSKCIEKINDLVISKEE
                     V"
     gene            1285..2076
                     /gene="asrB"
                     /locus_tag="KRH23_003141"
     CDS             1285..2076
                     /gene="asrB"
                     /locus_tag="KRH23_003141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0016002 - sulfite reductase activity
                     [Evidence IEA];
                     GO_process: GO:0006790 - sulfur compound metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic sulfite reductase subunit AsrB"
                     /protein_id="HHS5226418.1"
                     /translation="MNPYIPVSAKILDIVKHTDKEWTFRVNCNTKSVLPGKFYEISIP
                     KYGESPISVSGYGEDYIDFTIRNVGKVTSELFNYKEGDSFFIRGPYGNGFDVSLYEGR
                     EIVVVAGGSALAPVRGIVEYFYNNKEKCEKFKLIVGFKSPKDILFADDLKRWSKKLDI
                     LVTVDGAEEGYSGNVGLVTKYIPELDMKDINNTSIVVVGPPMMMKFTVEEFLKRDLDE
                     KNIWVSYERKMCCGIGKCGHCKMDDTYICLDGPVFDYSYAKNLID"
     gene            2089..3060
                     /gene="asrC"
                     /locus_tag="KRH23_003142"
     CDS             2089..3060
                     /gene="asrC"
                     /locus_tag="KRH23_003142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016002 - sulfite reductase activity
                     [Evidence IEA];
                     GO_process: GO:0006790 - sulfur compound metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite reductase subunit C"
                     /protein_id="HHS5226419.1"
                     /translation="MIRDLNTKKVMKNAYRITKTKYETSLRVRVPGGLIDPESLAVVS
                     KIASEYGNGQVHITTRQGFEILGINMEDMEEINKIIQPVIEKMNINQSEKNAGYPAAG
                     TRNIAACIGNKVCPKAQYNTTEFAKRIEKAIFPNDLHFKVALTGCPNDCIKARMNDFG
                     IIGMALPIYEKDRCVNCGACVKKCSKISVGALKTENNKVVRDKDKCIGCGECVLNCPT
                     NAWTRDEKKYYRLAIMGRTGKKNPRLAEDFLLWVDEDSIIKIILNTYRYVEKYIDKDA
                     PGGKEHIGYIIDRTGFMEFKKWALEGVELPEITKMYENIYWSGIKYL"
     gene            3117..3893
                     /locus_tag="KRH23_003143"
     CDS             3117..3893
                     /locus_tag="KRH23_003143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HHS5226420.1"
                     /translation="MHKETLDKLTNAAINKINLLNTSKVKYLVSSAFAGLYVGIGILL
                     IFTIGGLLTDAGSPMTKIVMGLSFAIALSLVIMTGTELFTGNNMVMSAGMLNKGVSIK
                     DTSKIWAYSWVGNLIGALVLGIIFVGTGLVDKGPVAEFFANTAASKASMPFTALFFRG
                     ILCNILVCVSVLCSFRTNSDTAKIIMIFLCLFAFITSGFEHSVANMTIYSVSLFSPAI
                     STVTIGGAIYNLVAVTLGNIVGGALFMGLGTYILGKEKLN"
     gene            4164..6182
                     /locus_tag="KRH23_003144"
     CDS             4164..6182
                     /locus_tag="KRH23_003144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HHS5226421.1"
                     /translation="MTKKLVISKTKLFIFIIAFISIFIYLFGSKNTLIGVGIVTAMLT
                     LLERDLTISPIKNLLKYLAINIILGILSFFAVQNMYLGVLLNFIALFIIGYVFSYDLK
                     RAVYVPFGLMYIFMVSIPVGKSEFPMRLSALAIGAVIIMIAQFVMNRNRMKNVGDKEL
                     ISICDELLEKISLLKNTINDDSSIIKSSMRKIDSCNYRINSISKNLKMVIFDNRKDDF
                     YISIRGIDIMNILFSLERISLILERYKKDSKEFEDEDIKNILEESSINSKSDVLGVAT
                     KEINYIKMCLENKDTITDKEILGFRDYVIAQDTKNINLKEIYSVLENLYEFLVDYKKV
                     KSRDEKKAERKSKIPHEFKRLSIYKKNFNLNSIRFSYAVKIALATAVAGFIMDYFHLR
                     DGRWIMLTVFSLTQPYAENCIQRSRKRIEGTFIGAVIFIVLFSIIKDSTLRSLIVLLA
                     GYINSYVVDYRKLMVCVTVSALGSAVVMGDPNVLTISRISYVALGAIIALIVNKFILP
                     YDAKTGYQHVIEMYKGIVKNIIDEVNKSIENVADVYYIKNLLLIPSLIEDRLMLINAI
                     YKDKHQEDFLENQKLLISNMYNLYINVNKNKIKDEDVEKILRDTNYISNYNVDKYDEG
                     RSVILESIVNTKSLGDKIICLNLLQTLNGVKEMYRISNITKVSIKEAA"
     gene            6397..7254
                     /locus_tag="KRH23_003145"
     CDS             6397..7254
                     /locus_tag="KRH23_003145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HHS5226422.1"
                     /translation="MSKDVKVKRNKKYDTFSITMELERPLLYDEVENKDDKNNNRKFN
                     IKNKIFKGIGILFVLILLGFFIWINKTYEPQKLAKEALVSNSKVEVTVNENISFTPKG
                     RKVSKGLILYPGAKVEIESYAPLARKIAESGYEVVIVKMPLNLAILGTNKAQKVMDSY
                     NNIEHWVIGGHSLGGVAASNFARDNKLIEGVVFLASYPMGDELKELGKKVISIWGSKD
                     GVVNFKSLVESKQKLPDDTTYVEIEGGNHAQFGDYGKQKGDNDAIISQEKQLNITANS
                     IIKFLKNIS"
     gene            7351..8220
                     /locus_tag="KRH23_003146"
     CDS             7351..8220
                     /locus_tag="KRH23_003146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HHS5226423.1"
                     /translation="MEYDMPLYRPPSEAYSLIIQVTLGCSHNKCTFCSMYKSKKFKIK
                     PLEVIKNEIDIFRRYYKHVERIFLADGDALIIPMEKLRDIIIYIKEVFPECERITMYG
                     SPKSIEKKSDDELKELRKLGVKMIYLGLESGSNEVLEDIKKGFSSEQLIKVGRKVKKS
                     GIKLSATVIAGLGGTKKTHQHAVDTGKMLGAISPDYVGVLSLMVEPNTELYDLLKAGE
                     FTILEDKAVLQEIKEMIKNIDANEKIVFRSNHASNYANLKGVLPDDKQRLIDEIDYYL
                     SNQKLKREEYRRL"
     gene            complement(8591..9223)
                     /locus_tag="KRH23_003147"
     CDS             complement(8591..9223)
                     /locus_tag="KRH23_003147"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0046677 - response to antibiotic [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CatB-related O-acetyltransferase"
                     /protein_id="HHS5226424.1"
                     /translation="MTIPSSNKVYPRSNDYQTVYLKNVITRENIEVGDYTIYNDFYND
                     PRDFEKNNVLYHYPINNDKLIIGKFCSIACNAKFLMTSGNHSMKSKSTYTFPIFYEEW
                     KLDINHITDAWDNKGNIIIGNDVWIGYDSIIMSGVNIGDGAIIGTRAVVTNDVPPYSI
                     VGGVPAKIIKKRFNNDTISKLLEIKWWDWPYKKIQSNIKHIQSGNIDKLV"
     gene            complement(9298..9648)
                     /locus_tag="KRH23_003148"
                     /pseudo
     CDS             complement(9298..9648)
                     /locus_tag="KRH23_003148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009271880.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="integrase DNA-binding domain-containing protein"
     gene            complement(9726..9929)
                     /locus_tag="KRH23_003149"
     CDS             complement(9726..9929)
                     /locus_tag="KRH23_003149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HHS5226425.1"
                     /translation="MNNTDVPIWEKYTLTIEEASKYFRIGEKKLRKLADENLDSGWVI
                     MNSNRIQIKRKQFEKIVDTLDFI"
     gene            complement(10304..10534)
                     /locus_tag="KRH23_003150"
     CDS             complement(10304..10534)
                     /locus_tag="KRH23_003150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHS5226426.1"
                     /translation="MKPTKEVLPFTIILLAVHGDVNAINVILKHFEHYIIRLSQKTLF
                     DEYGNPYIHVEEETKRMLGTKLITAILRFNLS"
     gene            complement(10536..10889)
                     /locus_tag="KRH23_003151"
     CDS             complement(10536..10889)
                     /locus_tag="KRH23_003151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HHS5226427.1"
                     /translation="MRNYARDIYDENKRRNDYLVSLESLSLAELSKLSILDDYDSNYI
                     CMVSYDYNIRIEDVLMAQAIGKLTKRKQDIILLSFFLNMTNADIATLMDLAENTIHYH
                     KTNALKELKELMQEH"
     gene            complement(11302..11751)
                     /locus_tag="KRH23_003152"
     CDS             complement(11302..11751)
                     /locus_tag="KRH23_003152"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HHS5226428.1"
                     /translation="MELIEWNYAYITELVEFANDKEIANNLRDNFPHPYREQNARDFI
                     SFCLATPDVKQLSYAIFYQERAIGSISLTFEEDTSINKNAELGYWLARNYWGKGIATN
                     AVKEICKIAFEKYNLNKIHANVYSYNRGSSKVLEKCGFKIEEYCHNS"
     gene            complement(11765..12691)
                     /locus_tag="KRH23_003153"
     CDS             complement(11765..12691)
                     /locus_tag="KRH23_003153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226429.1"
                     /translation="MSDILSRITNKIGDKNIVDKLSALSKSDLNSLLLEVFDRQANTL
                     TATDILKSYQLNRFTIPSGIDPEEIHALESKLLRKAFNMDIKTIMLSPSAPLGSCSVF
                     GSVDQYNVVSALRGTETLADPSNMLAIIIADKLKRKEENNTIPIHMATTARVIRAQNF
                     VGKGLYSHFGLYCMVSSGIDTGSYTCEKMLLEKHLNYYKDILSEIENVRFSIILRKRN
                     GYKDNDGFFDRMVETIKLIFPNIELSIHNDDVDNNYYKGINFKISVKQGNETVEIADG
                     GFVDWTYQMLGNKKERCLISGIGLERFLVTVS"
     gene            12919..13146
                     /locus_tag="KRH23_003154"
     CDS             12919..13146
                     /locus_tag="KRH23_003154"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226430.1"
                     /translation="MIVACNALTQLSYSWLATVFSNASIYWGASNSIFITPRGNLPKR
                     SCINGASTDCLKKDKKSIVSNSSLRPILVQA"
     gene            complement(13370..13990)
                     /locus_tag="KRH23_003155"
     CDS             complement(13370..13990)
                     /locus_tag="KRH23_003155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HHS5226431.1"
                     /translation="MHLIDFMNEDIKKKLVKKTYKKKETILFAEQENEYVILMIDGIA
                     EAFILNVKGNISTIHLYRSGSFFGEMEQFNDGKKPVEIVAFTDCNVYKLHRDDFLNWL
                     RGDFEATKFLIREISSKLVVNAELIEELSSLSVKERLLRCISLHYYRSELNLLTKKQL
                     ASEVNAPIRSINRAINECVQEHLIAYENKRFSVINQREVLKNLPTT"
     gene            complement(14089..14223)
                     /locus_tag="KRH23_003156"
     CDS             complement(14089..14223)
                     /locus_tag="KRH23_003156"
                     /inference="COORDINATES: protein motif:HMM:NF024056.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226432.1"
                     /translation="MKNYLTENLQQLNTEMVRSYIPTSSIVNSFPSLNLLCRKMTTGK
                     "
     gene            complement(14242..15356)
                     /locus_tag="KRH23_003157"
                     /pseudo
     CDS             complement(14242..15356)
                     /locus_tag="KRH23_003157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898619.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
     gene            15418..16263
                     /locus_tag="KRH23_003158"
                     /pseudo
     CDS             15418..16263
                     /locus_tag="KRH23_003158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009271880.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0009009 - site-specific recombinase
                     activity [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
     gene            16274..16423
                     /locus_tag="KRH23_003159"
     CDS             16274..16423
                     /locus_tag="KRH23_003159"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226433.1"
                     /translation="MTRVYYLFTTFDGILIRLNANLCKVSSKKKMSILLVDTGYIDIY
                     QLMKR"
     gene            16935..17702
                     /gene="aroD"
                     /locus_tag="KRH23_003160"
     CDS             16935..17702
                     /gene="aroD"
                     /locus_tag="KRH23_003160"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003855 - 3-dehydroquinate dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HHS5226434.1"
                     /translation="MKRKVQVKNITIGEGRPKICVPIIGKNKKDIIKEAKELKDACLD
                     IIEWRVDFFENVENIKEVKEVLYELRSYIHDIPLLFTFRSVVEGGEKLISRDYYTTLN
                     KEISNTGLVDLIDVELFMGDEVIDEVVNFAHKKEVKVIISNHDFNKTPKKEEIVSRLC
                     RMQELGADLPKIAVMPQNEKDVLVLLEATNEMFKIYADRPIITMSMSGMGVISRLCGE
                     IFGSALTFGAAKSVSAPGQISFKELNSVLNLLHKSIN"
     gene            complement(18030..18707)
                     /locus_tag="KRH23_003161"
     CDS             complement(18030..18707)
                     /locus_tag="KRH23_003161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226435.1"
                     /translation="MIVIEGSDKFKIAKEYIDVEYTLFSKVTFRYEKLKFKDNAELEK
                     IKMFKYKNGYIPNKLNLSFGYGFSSYKKQIIRETVDTLRLTEIFSSENIEDIKFIKDG
                     TKKLEISIEKVVKFKRRKKRNYVCCYCPDMYRDIKLDKESINKIYNRKIKIEREVNIF
                     EDEDVIINKKVLKFPKSWTKNMQKYWLSENKYPIHSTVIDDDRYKCCNVQYTKNRVII
                     LYYIYNH"
     gene            complement(18857..19174)
                     /locus_tag="KRH23_003162"
     CDS             complement(18857..19174)
                     /locus_tag="KRH23_003162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHS5226436.1"
                     /translation="MNYIGKRLKEERKKANLTSKEFANMVGVSPWYITQIESGKKNPS
                     LKTFIKFVNILNISADVLIKDITSTGKTYLENDINEELKDLNSRELNLISQIIDIIKK
                     NKI"
     gene            complement(19196..19534)
                     /locus_tag="KRH23_003163"
     CDS             complement(19196..19534)
                     /locus_tag="KRH23_003163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHS5226437.1"
                     /translation="MANIGKIIGDRIKVYRTKLGYSQEFLAEKAGLHPTYIGQIERAE
                     TNTSINIIMKIATALDIPLELLFANIITTEGVDNSVPLECYEMINKLTEKEQIAMLEL
                     IKCIIKYKEI"
BASE COUNT         7220 a         2535 c         3143 g         6889 t
ORIGIN      
        1 tgaattgtat aaaaaaacaa ataagattct tttttattca aaaaattgag tagatagtag
       61 ttttattgta cttaatgatt gtatttaagt gattagattt gaaatcgaat aatgtagata
      121 ataaaaaaat attaacagaa cttaataaac tccattaata ttttttttat tatttttgaa
      181 actgtgataa ttatcacgga agcatagaaa ataaagtgtt aagatttaaa caagatagca
      241 agtaagtaaa actaaaatat aagaaaggtg ataaaaatga aactaaaatt agattcatct
      301 aagttcaatg aaggtctgaa ttatctaaaa aaagactaca agatatttgc accagtttta
      361 atcccattta aaggtacttt ttcagatact gatgttataa gatacaagga ggtaaacgct
      421 tttgaagaaa tggaatttgc taagaaagca aacttttcac caaaagaagt tgtacttccc
      481 ataaatcaag tattgtttta ttttactgaa aaaaagttta aggaaagcga tttagacaac
      541 aagaaaattt taattttctt aagagcttgt gacataaatg gtataaaaag acttgatgaa
      601 atatatctaa ataatggtga agaaaaagat tatttttata aaaatatcag agataaagta
      661 aagtttgcac ttgtagggtg taaggaaagt tttagaaact gtttttgtgt gagcatggat
      721 tctaacaaaa ctgataatta ttcaattgga ttaaatatag aaggagatac actgtactta
      781 gatataaagg atagtgaatt tgaagtattt aatggagaag caactgaatt taatgttgat
      841 tatgtaactg ataatttaat atctgtagat gtgccagaga atattgattc aaatgaaatg
      901 ataggaaatt caatatggga tgaatatgat acaagatgta taggatgtgg tagatgtaat
      961 tttgtatgtc caacatgttc atgttttaca atgcaggata ttttctataa ggaaaacgaa
     1021 aatgtaggtg agagaagaag ggtttgggct tcttgtcaag tagatggata tacagatata
     1081 gcaggtggaa attcttttag aaaaaaacaa ggtgaaagaa tgagatttaa aactatgcat
     1141 aaaatacatg attttaaaaa aagattcgga tatcatatgt gtgttggttg tggaagatgt
     1201 gatgatgcct gtccgcaata catatcattt tcaaagtgta tagaaaaaat aaatgattta
     1261 gtaattagta aggaggaagt ataaatgaac ccatatatac cagtaagtgc aaaaatacta
     1321 gatatagtta aacatactga taaagaatgg acttttagag taaactgcaa tacaaaaagt
     1381 gtattgcctg gaaagtttta tgagatatct atacctaaat acggtgaaag tccaatatca
     1441 gtatcaggat atggagagga ttatattgac tttacaataa gaaatgtagg aaaagtaact
     1501 agcgagttgt ttaattataa agaaggagat tcttttttta taagaggtcc ttatggaaat
     1561 ggatttgatg tatcccttta tgaaggaaga gaaattgtag tagttgcagg aggaagtgca
     1621 ttagcccctg taagaggaat agttgaatat ttttataata ataaagaaaa atgcgaaaag
     1681 tttaaattaa tagtaggatt taaatcacca aaagatattt tatttgcaga tgatttaaag
     1741 agatggagta aaaaacttga tattttagtt actgtagatg gagcagagga aggatatagt
     1801 ggtaatgtag gattagtaac aaaatacata ccagaattgg atatgaaaga tataaacaat
     1861 acttctatag ttgtagttgg acctccaatg atgatgaaat ttacagtaga agaattttta
     1921 aaaagagatt tagatgaaaa gaacatttgg gtttcttatg aaagaaaaat gtgttgtgga
     1981 ataggtaaat gtggacattg taaaatggat gatacttaca tatgtttaga tggaccagta
     2041 tttgattatt catatgctaa aaatcttatt gattaggggg tgaagtttgt gataagagat
     2101 ttaaatacca aaaaagtaat gaaaaatgct tatagaatta caaaaacaaa atatgagact
     2161 tctttaagag ttagagtacc tggaggtctt attgaccctg agagtttagc tgtagtttct
     2221 aaaattgcaa gtgagtacgg caatggacag gtgcacataa ctacaagaca ggggtttgaa
     2281 atattaggaa taaatatgga agatatggaa gaaataaata aaattataca acctgttatt
     2341 gaaaaaatga atataaatca aagtgagaaa aacgcaggtt atccagcagc aggtacaaga
     2401 aatatagcag cttgtatagg aaataaagtc tgtccaaagg ctcaatataa tacaactgaa
     2461 tttgctaaaa gaatagaaaa agctatattt ccaaatgatt tacattttaa agtggcttta
     2521 actggttgtc caaatgattg tataaaagct agaatgaatg actttggaat tattggtatg
     2581 gctttaccaa tatatgaaaa ggatagatgt gtaaattgtg gagcatgtgt aaaaaaatgt
     2641 tctaagatat ctgttggagc attaaaaaca gaaaataata aggtggtaag agataaagat
     2701 aagtgtatag gctgtggaga gtgtgtacta aattgcccaa caaatgcatg gactagagat
     2761 gagaaaaaat actatagatt agctataatg ggtagaacag gaaagaaaaa ccctagacta
     2821 gcagaagatt ttcttttatg ggtagatgag gacagcataa taaagataat acttaatact
     2881 tatagatatg tagaaaagta tatagataaa gatgcaccag gaggaaaaga acatatagga
     2941 tatataattg atagaacagg atttatggaa tttaaaaaat gggcacttga aggtgtagag
     3001 cttccagaaa taactaaaat gtacgaaaac atatactgga gtggaattaa atatctataa
     3061 attgagtaaa acatatattt gaataaatta aaatttaata gaaggaagag ggaattatgc
     3121 ataaagaaac tttggataaa ttaactaatg cagctataaa taagataaat ttattaaaca
     3181 caagtaaagt aaaatatttg gtatcttctg cgtttgcagg actttatgta ggtataggta
     3241 tacttttgat atttactata ggaggacttt tgactgatgc aggttcacct atgactaaga
     3301 tagtaatggg gttatcattt gcaatagcac taagtttggt tataatgacg ggaacagagt
     3361 tatttactgg aaacaatatg gttatgtctg ctggtatgtt aaataaaggt gtaagtataa
     3421 aagatacttc taaaatatgg gcatacagtt gggtaggtaa tttaatcgga gctttggttt
     3481 taggcattat atttgtagga actggtctag tagacaaagg acctgtagct gaattttttg
     3541 caaatacagc agctagtaaa gcatccatgc catttacagc tcttttcttt agaggaattt
     3601 tatgtaatat tctagtatgt gtatcagtgt tgtgttcatt tagaactaat agtgatactg
     3661 caaaaataat tatgatattc ttatgtttat ttgcttttat aacatcaggt tttgagcata
     3721 gtgtagcaaa tatgacaatt tatagtgttt cattattttc accagcaata agtacagtta
     3781 ctattggagg agctatttat aatttagtag ctgtaacact tggaaatatt gttggaggag
     3841 ctttatttat gggtcttgga acttatatat tgggtaaaga aaagcttaat taaatttatt
     3901 gtataaatta taactctctt aataaataca tttttagtat tgttgagaga gttattttta
     3961 tatttttgaa aaaatatttg aaagaaaaaa tatatgggag catacgaaaa tatataaact
     4021 atatataaaa aaaatacgtt taaatatgaa ttatatagct ctaaacataa aaaaagttaa
     4081 agtcctgccg taaaagagtg cattttgaat aagataacaa atatgataaa attggtcttg
     4141 ttgaaatttt taggggggat atgatgacaa agaaactagt aatatcaaaa acaaagttgt
     4201 ttatttttat aatagcattt atttctatat ttatatattt atttggaagt aaaaatacac
     4261 ttataggtgt aggtatagta acagctatgc taacactcct ggaaagagat ttaactattt
     4321 ctccaattaa aaatttactg aagtatttag caataaatat aatcttagga atactatcat
     4381 tttttgcagt acaaaatatg tatttaggag ttttattaaa ttttatagca ttatttataa
     4441 tagggtatgt atttagttat gacttaaaaa gagcagtata tgtacctttt ggtctaatgt
     4501 atatatttat ggtaagtata cctgtaggaa aaagtgaatt tcctatgaga ttgtcggctt
     4561 tagctattgg agcagttata ataatgattg ctcaatttgt tatgaataga aataggatga
     4621 aaaatgtcgg agataaagaa ctgatatcta tatgtgatga attattagaa aaaattagtc
     4681 ttttaaaaaa tactattaat gatgatagtt ctataattaa atctagtatg agaaaaatag
     4741 atagctgtaa ttatagaata aattctatat ctaaaaattt gaaaatggtt atttttgata
     4801 atagaaaaga tgacttttat atcagtatta gaggtataga cataatgaat attttatttt
     4861 cattagaaag aataagttta atcctggaaa gatacaaaaa ggatagtaaa gaatttgaag
     4921 atgaagatat aaaaaatatt ttagaagaaa gtagcataaa tagtaaatca gatgttttag
     4981 gtgtagcaac gaaagaaata aactatatta agatgtgttt agaaaataaa gataccataa
     5041 ctgataaaga gatattagga tttagagatt atgttattgc tcaggatact aaaaatataa
     5101 atttaaaaga aatttatagt gttttagaaa atttatatga gtttttagta gattataaaa
     5161 aagtaaaatc aagagacgaa aagaaagctg aaagaaaatc aaagatacct catgaattta
     5221 aacgactatc aatatataag aaaaacttta atttaaattc tataagattt tcttatgcag
     5281 taaagattgc tttagctaca gctgtagcag gttttattat ggattatttc catttaagag
     5341 atggaagatg gataatgtta actgtctttt cattgacaca accttacgca gaaaattgta
     5401 tacaaaggtc tagaaaaaga atagaaggta catttatagg agctgtaata tttattgtat
     5461 tattttcaat aataaaagat agtacattaa ggtcgttaat agttctttta gcagggtata
     5521 taaactctta tgtagttgat tatagaaaat taatggtatg tgtaactgtt tcagctcttg
     5581 gttcagcagt agttatggga gacccaaatg ttttaaccat aagcaggatt tcatatgtag
     5641 cattaggagc aattattgca ttaatagtaa ataagtttat attaccatat gatgctaaaa
     5701 caggctatca acatgttata gaaatgtata aaggaatagt taaaaatata attgatgaag
     5761 tcaataagtc tatagaaaat gtagctgatg tttactatat aaaaaattta ttattgatac
     5821 catcacttat tgaagataga cttatgttga taaatgctat atataaagat aaacatcaag
     5881 aggatttttt agaaaatcag aaattactaa taagtaatat gtataatcta tatataaatg
     5941 ttaataaaaa taaaataaaa gatgaagatg ttgaaaaaat attgagagat actaattata
     6001 tttcaaatta caatgtagat aagtatgatg aaggaagaag tgtaatttta gagagtattg
     6061 taaatactaa aagtctaggt gacaagataa tatgtctaaa cttactgcaa actctaaatg
     6121 gtgtcaaaga aatgtataga ataagtaata taactaaagt ttcaataaaa gaagcagctt
     6181 agatattaaa ttatagaata gccatatatt taaaataaag tatatggcta tttgttttat
     6241 aaaatactaa aagaaaataa tatataaaaa acaaaaaaca tatatttatg aattttatat
     6301 gaaaatagtt aaaatattga tttttttcat tggttgaaaa aacaatttac ttaggataaa
     6361 ctataatagt attcaaatat tatgggggtt agatttatga gtaaagatgt aaaggtaaag
     6421 cgtaataaga aatatgatac atttagtata actatggaac ttgagagacc tttactttat
     6481 gatgaggttg agaacaaaga tgataaaaat aataatagaa aatttaacat aaagaataag
     6541 atatttaagg gaataggtat actatttgta ttgattttgc ttggcttttt catatggata
     6601 aataaaacat atgaacctca aaagctggca aaagaagctc tagtcagcaa tagtaaagtt
     6661 gaagtaactg taaatgaaaa catttcattt acaccaaaag gaagaaaagt ttctaaaggt
     6721 ttaattttgt atccaggagc taaagtagaa atagaatctt atgctccact tgcaagaaaa
     6781 atagcagaaa gtggatatga ggttgtaatc gtaaagatgc cacttaatct agctatactt
     6841 ggaactaata aggcacagaa agttatggat tcttacaaca acatagaaca ttgggtaata
     6901 ggaggtcatt cattaggagg agttgcagca tcaaattttg cacgtgataa taaattaatt
     6961 gaaggcgttg tatttttagc ttcttatcca atgggtgatg agttgaaaga attaggaaaa
     7021 aaagttatat ctatatgggg gagcaaagat ggagtagtca attttaaaag tcttgtagaa
     7081 tcaaaacaaa aacttcctga tgatacaact tatgttgaga ttgaaggagg aaatcatgca
     7141 caatttggag attatggaaa acaaaaggga gataatgatg ctattataag tcaagaaaaa
     7201 caacttaata ttactgccaa tagtatcatt aaatttttaa agaatatatc ttaaactaaa
     7261 atttaaaaaa tataatttta taagttatta tttaaagtaa atattaataa tataatagaa
     7321 tgaatatttt attacaaggg ggattttaat atggaatacg atatgccact ttacagacca
     7381 ccaagtgagg cttatagtct tataatacaa gtcacactag gatgttctca taacaaatgt
     7441 acgttttgta gtatgtacaa atctaaaaaa tttaaaataa agccactaga agtaataaaa
     7501 aatgaaattg atatatttag aagatattat aagcatgtag aaagaatatt cttagcagat
     7561 ggagatgcat tgataatacc aatggagaaa ttaagagata ttattatata tataaaagaa
     7621 gtttttccag agtgtgaaag aattactatg tacggctctc ctaaatctat agagaaaaaa
     7681 tctgatgatg aacttaaaga attaagaaaa cttggtgtta aaatgattta tctagggctt
     7741 gaaagtggaa gcaatgaagt attagaagat attaagaaag gttttagtag tgaacaatta
     7801 ataaaagttg gtagaaaagt taaaaaaagt gggattaaat tatcagccac tgtaatagca
     7861 ggtcttggag gaactaaaaa aacacatcag catgcagttg atacaggaaa aatgttagga
     7921 gcaatttcac cagattatgt gggtgtactt agtttaatgg tagaacctaa tactgaactt
     7981 tacgatttac ttaaggcagg agagtttaca atactagagg ataaggctgt gttacaagaa
     8041 attaaagaga tgataaagaa tatagatgct aatgaaaaaa ttgtatttag aagtaatcat
     8101 gcatcaaatt atgctaattt aaaaggtgta ttacctgatg ataaacaacg tctaattgat
     8161 gaaattgatt actatctaag taatcaaaag ctaaaaagag aagaatatag aagactatag
     8221 tttttgatat atcaatctat attgataggt aaatactaag attatttaga tacaaaaaat
     8281 catgctacat taatagttgc ttactattga tgtagcatga tttttttatt aaaaaacaaa
     8341 atggtatatt catatataat atatcaataa taatgaaaat gtgaactagt ttaatagaat
     8401 tttacctatt ataataaaaa caggaattta aacaataaaa agtaaagtaa ctttttatta
     8461 agtaacttta ctttttattt tatttaatgt tgtattaaat ttatatatat taaaataata
     8521 tacaaatttt gaaaaagctc ttataaaatg attattaaag taaagtttaa tataaataaa
     8581 ttataaaata ttaaactaat ttatcaatat ttcctgattg aatatgctta atgtttgatt
     8641 gaattttttt atatggccaa tcccaccatt taatttctaa taattttgaa attgtatcat
     8701 tattaaatct cttttttata atttttgcag gtactcctcc aacaatagaa tacggtggaa
     8761 cgtcattagt aactactgct cttgttccaa taattgcacc atcaccaata tttacacctg
     8821 acataattat agaatcataa cctatccaca catcatttcc aattataatg ttacccttat
     8881 tgtcccaagc gtccgttata tggttgatat cgagtttcca ttcttcataa aagatgggaa
     8941 aagtatatgt ggattttgat ttcattgagt gatttccact agtcattaga aattttgcat
     9001 tacatgctat tgagcaaaac ttaccaatta ttaatttatc attgtttata gggtaatgat
     9061 acaatacatt gtttttctca aaatctcttg ggtcattata aaagtcatta tatattgtgt
     9121 aatctccaac ttctatattt tcccttgtta ttacattttt aagatataca gtttgataat
     9181 cattacttct tggatatacc ttatttgaac ttggaatagt catatttaaa tctctccttt
     9241 aatatatatt atgtttttga ctattccact actacaatac atctcttcac agaatcactc
     9301 cttgttaaga atcttcataa gataatggcg tcctttttta gtgttaagtc ggatattctt
     9361 tcttagtcca ttctttttag cgtataactg acaaactgtc attttcttac caatagtgtc
     9421 aatgctatca tcaaggtcat tttgtattgc tttttcctta tcccttaatg atatatcatc
     9481 acgttttccc tttgggggtt tatcagtagg tacaagtttc caagagtaaa caaattgtgg
     9541 tttaccaaat gaatatacat acttatatgc gtatcttcca tcttttctct ggctctctcc
     9601 agttcttaaa attctatctt tattatctcg tcttttttca gttgacatga taagaagctc
     9661 ctctcaataa ccgaattgag cttgatacgt catatgaata ttataacata taaggctcaa
     9721 tttcattaga taaagtcaag tgtatcaacg attttctcaa attgttttct ctttatttga
     9781 atgcgattgc tattcataat gacccagcca gaatcaaggt tttcatcagc aagtttacgt
     9841 aattttttct ctccaatacg aaagtatttt gacgcttctt caatcgtcaa ggtatatttt
     9901 tcccaaatag gtacatcagt attgttcata gaatgtatca ttcctttcta tgttcgtagt
     9961 tcagaagtag atagatggct ttggtaagct ccactggtat ttcaaccaat cccattctta
    10021 tgggcccgtg tcatacaggt gtatcattat actgtggtac aggttacggc aaaacaaccg
    10081 ttccaaaggt cattatatag tcgctctctt gattaaggtc atggcgtata gtatttgttg
    10141 gctatctgta tcacaaacgt atctatctac tttattcagt tgtcaaagaa cagtcggcat
    10201 tgatttgcct ataaaaaatc acaatagctt gtgggctttt atagacaaat aattagtgat
    10261 tctccatgta ccaaatagct tgatacatgg agagagggcg agattaagac aaattaaatc
    10321 tcaaaatagc agtgattagt tttgttccta gcattcgctt tgtttcttct tctacatgaa
    10381 tatagggatt tccgtattca tcaaataaag ttttctgtga aagacgaatg atatagtgtt
    10441 caaaatgttt aagtattacg tttattgcat ttacatcgcc atgtacagca agtaaaataa
    10501 ttgtaaaagg taatacttct ttagtaggtt tcatttcaat gttcctgcat gagttctttc
    10561 aactctttta gtgcatttgt tttgtgataa tgtatggtat tttctgctaa atccatcaat
    10621 gttgctatgt cagcatttgt catgttgaga aagaatgaaa gtagaattat atcttgtttt
    10681 ctttttgtaa gttttccgat tgcttgcgcc attaatacat cttcaattcg tatgttgtag
    10741 tcgtaagaaa ccatacagat gtagttagaa tcataatcat ctaaaatact caatttactt
    10801 aattctgcaa gtgacaaaga ttcgagagat accaaataat catttctgcg tttattttcg
    10861 tcataaatat ctctagcata gttacgcaaa actgttttac agaaactgtc gaattgatgt
    10921 tcaattgtct tttcatcaac cataagattt caccctcttt ccatcgcaag gagttaaata
    10981 accttgctta ctcctatcac ggtgggaggg cgttaaatct tcgataaatt tcaaaaaaag
    11041 agaaaaaaat acacactctg cctatagggc aaaaatgtgt attctttaaa acgtatttaa
    11101 tttatattgg ttgtaagcca ccaccatatt gatgtatgga aatatgcatt ggctagcttt
    11161 tcataaaaat acaaagatgc ataagaaatt aatagagggg aaaaacttat tctgttatta
    11221 aaaagtaggt taattctaat aaatgctatt gcggtcgaat taaactatat acatggcaat
    11281 caatcatgtt tctattcttt attatgaatt gtgacagtat tcttcaatct taaaaccaca
    11341 tttttccaat actttacttg accctctatt gtaggaatat acattagcat gaattttgtt
    11401 aaggttgtat ttttcaaagg caattttgca tatttctttt actgcatttg ttgctatccc
    11461 tttgccccaa tagttcctag caagccagta acctaattca gcatttttat taatagaggt
    11521 atcttcttca aatgttaggc tgatacttcc aatagccctt tcttgataaa aaatagcata
    11581 gctaagttgt ttaacatctg gagttgccaa acaaaaacta ataaaatctc tagcgttttg
    11641 ctccctataa gggtggggga agttgtcacg aagattgttt gcaatttctt tatcattcgc
    11701 aaactcaact aactcggtaa tataagcata attccactct ataagttcca tttttcttct
    11761 ccttttatga aacagttaca agaaatcttt ctaagccaat accacttatc aaacagcgtt
    11821 cttttttatt tccaagcatt tgataagtcc agtcaacaaa tccaccgtca gctatttcaa
    11881 cggtttcatt tccttgtttg accgatattt tgaaattgat acctttataa taattattat
    11941 caacatcatc attatgaatt gataactcta tattaggaaa aataagtttg atagtttcaa
    12001 ccattctgtc gaaaaatccg tcattatctt tgtatccgtt tcttttgcgt agaataatag
    12061 agaaacgaac attttctatt tcacttaata tatctttata atagtttaag tgcttttcta
    12121 acaacatttt ttcacaagtg taagaccctg tatctatacc agatgaaacc atacaatata
    12181 agccaaaatg tgaatataaa cctttaccta caaaattttg tgctcttatt accctagcag
    12241 tagtagccat gtggataggt atggtattat tttcttcttt tctttttaat ttatcagcaa
    12301 taattattgc caacatattt gaggggtctg caagtgtttc tgtccctcgt agagcactta
    12361 ctacgttata ttgatctacg gagccaaaaa cgctacagct acctaatgga gcagagggag
    12421 aaagcataat cgtcttgata tccatattga atgcttttct caataatttt gattccaaag
    12481 cgtgaatttc ttctggatct ataccgctag ggatagtaaa tctatttagt tggtatgact
    12541 ttagaatatc agttgcagtt aaagtatttg cttgtctatc aaacacttct aatagaagtg
    12601 agttcaaatc tgattttgat agagctgata acttatcaac tatattctta tccccaattt
    12661 tatttgtaat tctacttaaa atatcactca tagttatcct ccatactgtt actttcaaaa
    12721 taattataga atggttacaa caactaatct aggtcatttg accaaaaatg aaaaaacact
    12781 gaatatttac tattcaatat ttttttactt tgggtttatt tgattaaatc ttgaaaatac
    12841 tgtaatgcaa ctctttcagc ttcaaccttt cggacaatag gactttgtga taattcctct
    12901 cttaactcaa gatacaggtt gatagtagcc tgcaatgcat taacacagct ttcatattca
    12961 tggttagcaa ccgtcttttc taatgcttca atatattggg gtgcgtccaa ttcaattttt
    13021 ataactccac gaggtaattt acctaagaga agctgtatta atggggcaag tactgattgt
    13081 cttaaaaaag ataaaaaatc aattgtttca aatagttctc tacgtccaat cttagtgcaa
    13141 gcgtaatgaa cccaaatcca aaatctatct tcaatccact gtaagtctgg agttgggaag
    13201 tatgcttctt ttttagtata acacctctca ctttctttta ttagctatca atccaacata
    13261 attatgcata ggagtattat ataatgaaga aataaaaaaa aataggtcac ttgacccgaa
    13321 ataaaaaagt attgaataat tattatccaa tacttttttg aaattatact tatgttgtag
    13381 gaagattctt taatacctct cgctgattaa ttacactaaa tcttttgttt tcataagcaa
    13441 ttagatgttc ttgtacacat tcatttatag cacgattaat gcttctaatt ggagcgttta
    13501 cttcgctagc aagctgtttt ttggtaagca gatttaattc acttctataa tagtgtaagg
    13561 atatacacct cagaagtcgt tctttaacac ttaaagatga taattcttca attaattcag
    13621 catttacaac taatttacta gatatttctc gaatcagaaa ttttgtagct tcaaaatcgc
    13681 cccttaacca gtttaaaaaa tcatctctat gaagtttata tacattacaa tctgtgaaag
    13741 cgacaatttc aacgggtttt ttcccatcat taaattgttc catttctcca aaaaaactac
    13801 cacttctata aagatgaata gttgagatgt ttcctttcac atttaagatg aatgcttctg
    13861 caataccatc aatcataaga attacatatt cattttcttg ctcagcaaaa agaatagtct
    13921 ctttcttttt atacgttttt ttaacaagct tctttttaat atcttcattc ataaaatcaa
    13981 ttaaatgcat attcatccct ccttaccaaa tctttgatta aattatatca tctttcaatt
    14041 agttaggtaa gataataaaa atatatttac atagaaacta ttccattatt attttccagt
    14101 tgtcattttt ctgcaaagta agttcaaact gggaaagctg ttgacaatag aactagtagg
    14161 aatatacgag cgaaccattt cagtattcaa ctgttgtagg ttttcagtca gataattctt
    14221 caaacgttca attcgtttgt cctgtgaatc ttgcgatgct ctaaccagtt tcatagatag
    14281 cgttttacct tgtgccacct gcaaaaaaga ccatgcttcg tcaaggtcaa ctatcttgaa
    14341 gatagagcgg tcagtatgaa taaagtctaa tacaaaggta ctaataacaa tcaacatagc
    14401 aacactaaga agttctattg ttgtatattc ttcaaaacta gtgtcggcat ctggcaatac
    14461 gaggtcagca acttgaataa tgttcagctg tttctccaag ctgatagact gcttcacatt
    14521 tccatcacta aacagtagat gtgcaaaatc atagtctaca aaactttcga tatggtcggc
    14581 tatgctgtta ctgatagaag tatcttcttt tcgtaattca tcaataacaa gtaataaccc
    14641 ccgctgttca ctttgggtta cattgcggat tgcttttcta agcactggga acttatcact
    14701 gtcacgactg gagataccag caagaatgtt aggatatcaa tcgctaaact ttcagaatca
    14761 tttttacggc tcaaaatgac gtaagggtca agcaatcctt tgttttcatc attactggtt
    14821 aaattgacaa tgtttatctc atgggctatt tctggtagcg tttctttcca tttgccgcgt
    14881 tctgctttag ggtcaactat gaccgcctgt ccgccgaata gtaccgcata gtaaacaagc
    14941 atattgttac tgaataattt accaccaccc aatgaaccga taaacgcaga cgctaacgca
    15001 ttggtaatag aaccctttac cccttgacta gcaagggcag gttttagata gacattcttt
    15061 ccagtgtcca gattgtagct aagatagata tcctcatgtt cgccaagggt ttgtgtcgct
    15121 ccaaaaccaa gtccagccaa aaaatccgaa gtgacatatt gaatataatc attgatgtaa
    15181 cgtttgctga caggaataaa ttcgccatgc aatcccaaca tatccccaaa gggacgcacg
    15241 agcttgattg ataagtcgtc gtaaaagtct ttgacttcat cacaacgcct ttttagctcg
    15301 tcaagatcct ttgtagatac acggacaaca tagctaagtt tatacataga ttctttacag
    15361 ttaaaagtct gtttttaaaa aaatgtataa attataaatc aaaatataga tactatcaat
    15421 gacccactag gtgcaaaaag cattgatatg gttaaattat cagacgctaa aagctgggct
    15481 atccgaatga gtgaagatgg gtgtgcttat aaatccattg acaattataa gcgctcactg
    15541 aaagcgtcgt ttttcatggc aattcaagat gactgtatta gaaagaatcc atttaatttt
    15601 cagttaagtg atgttttgga agatacaaca gaaccaaaaa tcgctctaac accagaacag
    15661 gaaatgggct tattatcctt tatggagagc gataagactt attgtaaata ttatgatgat
    15721 gttgttatcc tattagaaac aggactacgc atttctgaat tatgcggttt gactttagaa
    15781 ttagatatga aaaataaagc cattatggta gaccatcaat tgttgagtga tactaagatt
    15841 ggctattatg tagaagttcc aaagaccaca cagggtaagc gagaaattcc aatgactgaa
    15901 agagcttatc aatcatttga acgtatcgtt gaacggcgta agaacgctaa agcagaacca
    15961 atcattgttg atggttacca gaacttccta tttcttaaac aagatggatt accaaaacaa
    16021 gcaactcatt atcaaagcat gttaagagcg ttagtcaaga agtataacaa gacccatgag
    16081 gacaagctac caaagattac gccacatacc tttaggcata cactctgtac aaatatggct
    16141 aacaaaggaa tgagtactaa tatattgcaa tatattatgg ggcataaaaa cattactatg
    16201 acgcttggct attatgcaca tggttcattt agttctgcga gagctgaaat ggaacggtta
    16261 taagcctagt agtatgacta gagtttacta cttatttact acttttgatg gcattcttat
    16321 acggttaaat gccaacttat gcaaagtatc ttccaaaaag aaaatgtcga tactccttgt
    16381 agatacagga tatatcgaca tttaccaact tatgaaaaga taatcaaatt taatataagt
    16441 ttttcaaata aaaagatact aaattctttt tcgagaatct atataacatt acttaagctt
    16501 ggttggggta taaacaattg agtagctact tttgtatggt gttcaacttt agtcaaaact
    16561 cttaaataat gcaaatgatt tagattcatt aatattcaat ctcttcataa gtagtgaaat
    16621 tcgagttatt tctgcataat tatactatga tttatagatt aattctatta gcatccagaa
    16681 taatattgtt tatatgaata aaatttaaag aatattatga aaattatagg atgttaaaat
    16741 aaatttaggt aaaaaagaag tgtttgtata ttatagagta ccttttctaa aatatgtggg
    16801 attgttttaa gaattagaat aaaaattatt tttaaattag tatttttata atgtatagta
    16861 tttttaatgt ataattaaat tgtgcagaaa atagaattta aagtcctata aaatttctga
    16921 ttatggagga gaatatgaaa agaaaagttc aagtaaaaaa tattactatt ggagaaggta
    16981 gacctaaaat ttgtgtacca attattggga aaaataaaaa agatattata aaagaggcta
    17041 aagagttaaa agatgcatgt ttggatatta tagagtggcg agttgatttt tttgagaatg
    17101 tagaaaatat taaagaagtt aaggaagttc tctatgaatt aagaagttat atacatgata
    17161 tccctttatt attcacattt agaagtgtag tagaaggggg agaaaaatta atatcaagag
    17221 attattatac tactttgaat aaagaaattt ctaatacagg tttagtagat ttaatagatg
    17281 tagagttatt tatgggagat gaggtcatag atgaagtagt taattttgct cataaaaaag
    17341 aagtgaaagt aattatatct aatcatgatt ttaataaaac tccaaaaaaa gaagagattg
    17401 tatctcgttt atgtagaatg caggaattgg gcgcagattt acctaaaata gctgttatgc
    17461 cgcaaaatga aaaagatgtg ttagtgctac ttgaagctac aaatgaaatg tttaaaattt
    17521 atgcagatag accaataata acaatgtcaa tgtcaggaat gggtgttata agtagattgt
    17581 gtggtgaaat atttggttct gcattgactt ttggagctgc aaaaagtgtt tcagcaccag
    17641 ggcaaatatc atttaaagag ttaaattcag tacttaatct attacataag agtattaatt
    17701 aaattaatta tatagaaata ttagacggta tttttgaaga tataaattaa atataaaaaa
    17761 cttttcagat agtaaaattt aaattgggca attatatctg aaaagcaact atttagtgtg
    17821 tattttgaaa gtgatataga aaatcttata aatcaactat ggcatattta aaatatgcca
    17881 ttaaaaccta ctagacatta gattatagat ggtatactag catttctatt atttatagat
    17941 agtaagtttt tataataact gttttatcta aagtagaaga tatatttgta ttatgtatat
    18001 ttgtcattat ttttttgtaa ttatgtatat taatggttat atatgtaata taatattatc
    18061 actctatttt ttgtatattg tacattacaa catttatatc tatcatcatc aattacagta
    18121 gaatgtatgg gatacttatt ttcacttaac caatattttt gcatattctt tgtccaagac
    18181 tttggaaact tcaatacttt tttgtttatt ataacatcct catcttcaaa aatattaact
    18241 tctctttcta tttttatttt tctgttgtat atcttattga tagattcttt gtcgagtttt
    18301 atgtctctat acatatcagg gcaatagcaa caaacataat ttcttttttt tcgacgttta
    18361 aatttcacaa ctttctctat gctaatttct aatttttttg taccatcttt tataaattta
    18421 atatcttcta tgttctcgct tgaaaaaatt tctgtcaatc ttaaagtatc tacagtttct
    18481 ctaattattt gctttttata agaagagaat ccatatccaa aagaaaggtt taatttatta
    18541 gggatgtagc catttttata tttaaacatc ttaatttttt ccaattcagc attatcttta
    18601 aatttcaact tttcatacct aaaagttact ttgctaaaaa gagtatattc tacatcaata
    18661 tattcttttg caatcttaaa tttatcgcta ccttcaatca caatcatagc ctatctccaa
    18721 tcgttttata ttaaaataag gccatagaac atggtctaat agtactcatt agcactataa
    18781 gacaatgtta acacaaaaag acaaaaaaag gttatttatt tcaaataacc ttttttttta
    18841 tataaaatat aaagaattat attttattct tttttatgat gtctataatc tgtgatatca
    18901 gatttagttc tcttgaattt aagtctttta actcttcatt tatatcattt tctaaatatg
    18961 tttttccagt ggaagtaata tcttttataa gaacatctgc agaaatattt aatatattta
    19021 caaattttat gaatgtttta agacttggat tctttttacc actttcgatt tgagttatat
    19081 accaaggcga tactccaacc atatttgcaa attcttttga agttaaattt gcttttttcc
    19141 gttcttcttt aagtctttta cctatataat tcattattgt tactatttcc ctcacttata
    19201 tttctttgta tttaatgatg cactttatta actctagcat tgcaatttgt tctttttcag
    19261 ttaatttatt aatcatttca taacattcta aaggtacaga gttatcaacg ccttctgttg
    19321 taataatatt tgcaaataac aattcaagtg gtatgtctaa agcagtagca attttcatta
    19381 taatattgat agatgtattt gtctcagctc tttcaatctg accaatatat gttggatgta
    19441 aacctgcctt ttctgctaga aactcttgac tatatcccaa ttttgttcta tagactttta
    19501 ttctatctcc tattattttt cctatatttg ccaattatta tccctccact ttagattata
    19561 ttcatagttt aagttgtttt atatagacta tttatacttt tttagtctaa atatagacta
    19621 tatatgtttt tatactgaaa taagtgctat ttatttttgt atagtctgta tctacaataa
    19681 acaaatatgg ataaatcata tttttaatta gagaaatatt ttcataattt catagccata
    19741 ctacaataat aaaacgaatt aataatatgt taattatagc atttttt
//
LOCUS       DAEORM030000066        19483 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.066, whole genome shotgun sequence.
ACCESSION   DAEORM030000066 DAEORM030000000
VERSION     DAEORM030000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 19483)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19483)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 19483)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19483
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.066"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            872..2452
                     /locus_tag="KRH23_003164"
     CDS             872..2452
                     /locus_tag="KRH23_003164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional ADP-dependent NAD(P)H-hydrate
                     dehydratase/NAD(P)H-hydrate epimerase"
                     /protein_id="HHS5226438.1"
                     /translation="MLIGTSKLSRNVDTACVEEVGIPMIVLMENAVISAMKNMDIDMY
                     NSYTVVCGVGNNGGDGLGIARHLNTYGKEVNVFLVGNLEKLSECSKINYNVLLNMGIN
                     IININKNDLSEKNYGDENEVDKIIKVEKQNIIKNKNLTIFKDRVSKSDVVVDAIFGTG
                     LKRDITGIFKEVIDIVNDNSKNTYSIDIPSGIDSDNGNVLGTCIRANKTISFEFYKRG
                     FLNYDTSTLIGDVVVEKIGVPDFITRKYHDEEFITDKTFVKNNIRRRDKHGFKSDFGK
                     VSIVAGSKGFYGASFIATESAVKSGSGLVTLISSEDVQEKVSIRLTEAMTLNFEEERL
                     NKLLNSSDAIGFGPGMGDNSQTFDKLLKIVENSNCPIVLDADGLNVMKDRCYKFLEWK
                     NRFVITPHLGEMARLTGDSIGYIREHRVDVAKEFAQKYNLVVLLKGYQTVITDGKKTY
                     INPTGNSCMATGGMGDCLLGMITSFIGQGMDILEATVSGAYIHGYIGDKLSKAMYTVN
                     ATDLISNISLTMKELLDI"
     gene            2626..3072
                     /locus_tag="KRH23_003165"
     CDS             2626..3072
                     /locus_tag="KRH23_003165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NfeD family protein"
                     /protein_id="HHS5226439.1"
                     /translation="MKLIWLIVAVLFGIAEMLTPSLTLIWFSVGAVILIFLSSFIESI
                     FLQILIFAVISIAMLVVATKKIVKKDKGYKSNTNLQAMMSKKGIVTEEISPNNTGLVV
                     VEHETWTAISIDGEKIEKGSTVEVLKIEGVKLVVKKVDATVNVTNQ"
     gene            3093..4136
                     /locus_tag="KRH23_003166"
     CDS             3093..4136
                     /locus_tag="KRH23_003166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HHS5226440.1"
                     /translation="MGTKIVLSIVLIVVVVAISLTCIRVIKQSKVGIIMRLGKFQKVA
                     ETGVHFLIPFLDKMAYVIDLREIVIDFPPQPVITKDNVTMQIDTVVYYKVTDPVRYVF
                     EIANPIAAIENLTATTLRNIIGELDLDETLTSRDIINVKMRTILDEATDKWGIKVNRV
                     ELKNIMPPQDIQVAMEKQMRAERERREAILQAEGNKSAAILQAEGEKQSAILTAEAKK
                     ESMVRVAEGEKESAILVAEGEAEAIRQTAIAKAQGEAEMIKRTQMATAEGLKLVFSAM
                     KEADIDNNILALKSMEALEKMAEGKSTKLVLPSEAVNFLGTFKGIKEVMSDDNKEVLD
                     IKEVLNDNESLKK"
     gene            4907..6067
                     /locus_tag="KRH23_003167"
     CDS             4907..6067
                     /locus_tag="KRH23_003167"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008878 - glucose-1-phosphate
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0005978 - glycogen biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HHS5226441.1"
                     /translation="MKKEMLAMILAGGQGSRLGVFTKRIAKPAVSFGGKYRIIDFVLS
                     NCSNSGIDTVGVLTQYRPLILNSHIGMGSHWDLDRINGGVYVLQPFMNEKEGNWYNGT
                     AHAIYQNMDFVDTYNPEYVLILSGDHIYKMDYSKMLKFHKEKGSKATIAVIEVPWDEA
                     SRFGIMNTNEDSSIYEFEEKPSEPKSNLASMGVYIFDWKMLRNYFKEAEKNPEINYDD
                     FGKNLIPKMLEDNVGMYAYPFKGYWRDVGTIQSLWDANMDIIKSPETLDLADPKWKIY
                     TNTMAMPPQYIGKNANVHRSMIADGCRILGEVGNSVLSHGVVVGKGSKVIDSVIMPNV
                     VIGENVTIEKAMIGECATINDNVQIKNVNNEINVVSEYENIEPRCVLIEGGL"
     gene            6069..7199
                     /gene="glgD"
                     /locus_tag="KRH23_003168"
     CDS             6069..7199
                     /gene="glgD"
                     /locus_tag="KRH23_003168"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008878 - glucose-1-phosphate
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0005978 - glycogen biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HHS5226442.1"
                     /translation="MRNECLGIINLNKKGDPAINKLNYGRPIASTPIAGRYRIIDFAL
                     SNMINSGITKVGIFAKEKYRSLTDHIGSGKDWDLSRKKGGLSIFSPENTKYRNTYSHR
                     EGDIYTILANLDYIEKSEEEYILIAPSYMLCNLNYSQALEYHKKSHNDITIIYKNVNN
                     ANKDFAGNLTLNLDSNNRVINVGNNLGKFPRANICMETYIMKREDFVECIYNIVNKGN
                     YCYLEEFIIEEAENMKIGAYEYTGYLKCVNSVESYFEMSKDLLNLEVADELLYSERKI
                     FTKEKNESPTIYTDSAKVENSFIASGCLIEGTVKDSIIFRKVNVEKGTVIENSIVMQN
                     CVIKSNAKLYNAILDKNTSVSNGKELRGDEKYPLVVEKNTNI"
     gene            7228..8670
                     /gene="glgA"
                     /locus_tag="KRH23_003169"
     CDS             7228..8670
                     /gene="glgA"
                     /locus_tag="KRH23_003169"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004373 - alpha-1,4-glucan
                     glucosyltransferase (UDP-glucose donor) activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HHS5226443.1"
                     /translation="MKVFYVTAECWPFAKTGGLGDVSYALPKELKKEGVDVRVIMPKY
                     STIPSYLKDQLKEIAVFSVRVGWRNQYCGLLEMELDGVKFYFIDNEFYFRREDERKSI
                     YGYGDDAERYTFFTDAVLEAISRIDFYPDVIHINDWHTGMLPLILKERYATLEGYKNI
                     KTMYTIHNLQYQGVFDKHVLYDILDLPQKYFDNGDIEYYGSINFMKAGINFADKIITV
                     SPTYANEIQTSFYGEQLDGLLRKESGKLKGILNGIDYDLNDPAKDKDIFVHYDVDSID
                     KKVENKLRLQDILGLKKDSSIPLIGIVSRLVSQKGFDLIAYMMPELMREDLQIVVLGT
                     GEHQYQSMFNYYDSNFSDKVSARITFNASLAQQIYAASDMFLMPSLFEPCGIGQMLAM
                     RYGSLPIVRETGGLRDTVTPYNKFTGEGNGFSFKNYNAHEMFFCLKNAIKVFKDKEKW
                     IKLVENAMKTDNSWKKSAKEYIETYRDICD"
     gene            8684..11104
                     /locus_tag="KRH23_003170"
     CDS             8684..11104
                     /locus_tag="KRH23_003170"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan phosphorylase"
                     /protein_id="HHS5226444.1"
                     /translation="MVTISKKKFKQKFEVKMYSLYAQSIKEATDEQLLNVLCSLLKDE
                     IAKKWVATKLDKKKEVYYFSLEFLIGRQLKSNLLNLNIEEEVREGLSELGINLDDLIE
                     AEVDPALGNGGLGRLAACFLDSMASLNISGQGYGIRYKYGLFEQKFVNGYQVEVPDNW
                     LTEGRYAWETVRPNEATMVKFGGEVELIKEGSHLKVIHKNYLPVMAMPYDIPIIGYQN
                     QCINTLRLFKSEIPKRDFGELTSNALNYSGSYEEALKHKYYTEEISQVLYPDDSNYAG
                     KLLRLKQEYFFVSAGIQDIIRKYKKNKLNINNLFDKVAIHINDTHPTLCIPELMRILL
                     DEENLSWDEAWEITKKTVSYTNHTIMSEAMEKWPVSMMKELLPRIYMIIEEINRRYVE
                     ELNNKGYDQDRIKRMSIIDCDNINMANLCIVTSHSVNGVAKLHTHILETEVLKDFYQD
                     EPNKFNNKTNGIAHRRWLISSNPQLSNLITDLIGDSWKKDTLQLKNIEKFKNDSSVLQ
                     RLDDIKYNNKANLAKFIKDKYDLNVDPSSIFDVQVKRLHAYKRQLLNIFNVLHMYHEL
                     LDNPNLNLDPRTFIFGAKAAPGYYLAKCIIKFINSVASTINNDVRVKDKLKVVFLENY
                     GVSLAEIIIPAANVSEQISTTTKEASGTSNMKFMMNGAITLATLDGANVEICEQVGKE
                     NMFLFGLSAEQVLNYNKYGGYSSLDLYHSNMDIKRVVDDLINGFIPNLGEEGRSIYNS
                     LTTYNDEYFVLRDFENYGQAQADINRLYRDKEKWNKMSLVNIANSGFFSSDRTISEYA
                     KDIWFKRV"
     gene            11109..12974
                     /locus_tag="KRH23_003171"
     CDS             11109..12974
                     /locus_tag="KRH23_003171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 13 protein"
                     /protein_id="HHS5226445.1"
                     /translation="MQSVIEYNSWDKNFKAPFGALKFDEELTICVKVNEGYNIKSISL
                     EINREEEMRTITLNEELDNDKLGKCFCGKIEKFDGTGVYFYYFKVDVEMDGQIKTLFY
                     GKNRDNGYSCEYNYSDINKYQITVYKDFKVPTWYKEGILYHIFVDRFNNGNRSGKVDN
                     PKKNSFIYGNWEDTPMYIKDSQGDVIRWDFHGGNLRGIINKLGYLKKLGVSILYLSPI
                     FEASSNHKYDTGDYKKIDPMFGDEDTFKELIDKAKEKGISIVLDGVFSHTGADSKYFN
                     MYGNYNSLGAYQSKESPYYSWYMFEEFPQKYKSWWDVKTLPNINELEHSYMDYIIYDN
                     DSVINKWVNMGIKGWRLDVADELPTKFIRELKKELKTADDDSILIGEVWEDASNKISY
                     GQRRSYLLGEELDSVMGYPFRNNMFSFLKGEINSYELCNRYMQIKENYPKESFRSNLN
                     LIGTHDVTRAKTELNDDVDLVKLAVAIQMTFEGVPYIYYGDEAGLCGGVDPDNRRTYP
                     WKNEDEDMLNFYRDVIKIRNKNKLLSSGNTEFIYTNNDSVFSFIRVNENNDRILILVN
                     RSENVESISLCIESSFIEEIPIKYSLKNANSTIQIENNELKVDLDSKSFRIFRVN"
     gene            13219..13872
                     /locus_tag="KRH23_003172"
     CDS             13219..13872
                     /locus_tag="KRH23_003172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HHS5226446.1"
                     /translation="MKVDPLTTQVYDYISKKIQNGEYEANQRITESEICKSIGVSRTP
                     AREALTRLAGENLLEKIPNKGFVVKEFQEKEKLDTYSVIGVLDALAGSSALQNLTESD
                     LVKMEELTEMMAVSIKYKNYNSYLKLSNEFHDIYITKSDNQVLVNLLNSLRYNFMSKS
                     YTSDNEDELYKMLTYSNNQHIEVVKSMRENDLENVERILREHWKTIPMEEMKKEKLL"
     gene            13968..14567
                     /locus_tag="KRH23_003173"
     CDS             13968..14567
                     /locus_tag="KRH23_003173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HHS5226447.1"
                     /translation="MYPNKEIAIEELEVAGKMNPGPWIKHSYNVANVAKLIAEQCENL
                     NSEKAFVCGLLHDIGRRTGISSVRHIIDGYDYVISKGWDEVARVCLTHSFPVKDIEAD
                     IGNKDISKEQYDFINHYLNNLEYNDYDKLIILCDALADANGFCILEKRFVDTTRRYGI
                     YPFSVERWNKTYEYKEYFEKIINKSIYTLLPNIEKSIYY"
     gene            15157..16632
                     /locus_tag="KRH23_003174"
     CDS             15157..16632
                     /locus_tag="KRH23_003174"
                     /EC_number="4.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HHS5226448.1"
                     /translation="MDSEFANAVELSYECAPLLESLKEYSEKDIACFDVPGHVKNRGV
                     AILNKYLGESLMKMDINSSPTMDNVSAPNGIIKNAQDLLAQAYMADEAFFITNGTTQA
                     IHAMILSVIKPGEKVLLPRNIHKSVINALILCGGIPIFIQPEFDEKLGISLNITLEKV
                     RTEIEKDCNIKALFFLNPTYYGVCADLESIIELCHKNNVLVLVDEAHGAHFPFHLDLP
                     PSAISLGADMVAVSIHKTGGALTQSSALLLNRDNVSFEKVLQSINMLQSTSASYLLMA
                     SIDGARVNLVENGEKQLSKALNLSRYAKSKLNKIDGIKVLSIEILKQKGVKFIDETKL
                     CINVKELNLTGFEVYDLLYKNFSIQVELGDSYNILALVSIGTNKSDIDRLVKALSIIA
                     KIYRKESTLNEFNMVQINPIIKLNPREAFYAPKESVEINSCIDRICGESIMAYPPGIP
                     IIAPGELITEEIMEYIIFLKNSNAYLTDVQDKNLDRILVIK"
     gene            16719..17132
                     /gene="speD"
                     /locus_tag="KRH23_003175"
     CDS             16719..17132
                     /gene="speD"
                     /locus_tag="KRH23_003175"
                     /EC_number="4.1.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004014 - adenosylmethionine decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0008295 - spermidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylmethionine decarboxylase"
                     /protein_id="HHS5226449.1"
                     /translation="MKFETLGRHILVEYYNCDENVLKDPRLIENFMNDSALNAKATIV
                     DSVFHHFNPWGVSGAVIIAESHLTIHTWPEYGYAAADFFTCGDIDPWKSFELLEQLLK
                     SERSESTEIPRGLTTKIKKYSKKDLGKITHKPEAV"
     gene            17162..18013
                     /gene="speE"
                     /locus_tag="KRH23_003176"
     CDS             17162..18013
                     /gene="speE"
                     /locus_tag="KRH23_003176"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HHS5226450.1"
                     /translation="MELWYTEEWTENVRFSIKVNKHLFEGKSQFQRIDVFDSDEFGKF
                     LTIDGLMMVTYKDEFIYHEMITHVPMATNLNIKKVLVIGGGDGGTVRELSRYPQIEKI
                     DMVEIDKMVVDVSKEYMDICSCKLDDKRVSLYFEDGVNFVKCAHDKSYDLIIVDSTDP
                     IGPGEGLFSTDFYKDCYRILTDDGILVNQSESPYFDFNAKEMKRANKKLKQIFPISEV
                     YQAHIPTYPSGHWLFGFASKKLNPVKNQDRNGWEKLSLKTKYYNSDIHLGSFMLPQYV
                     KEMLDEE"
     gene            18003..18881
                     /gene="speB"
                     /locus_tag="KRH23_003177"
     CDS             18003..18881
                     /gene="speB"
                     /locus_tag="KRH23_003177"
                     /EC_number="3.5.3.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008783 - agmatinase activity [Evidence
                     IEA];
                     GO_process: GO:0008295 - spermidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="agmatinase"
                     /protein_id="HHS5226451.1"
                     /translation="MKNNFYHMNTFMSMDKNYEESNLIVFGVGFDGTTSNRPGARFAS
                     SSMRKEFYGLETYSPFLDLDLEDYNICDYGDLEISVGSTEQVLKEIYQETYKIVRDSK
                     VPFMIGGEHLVTLPAFKAVHEKYNDIYVIHFDAHTDLREEYNNSKNSHATVIKRIWDI
                     VGDNKIFQFGIRSGTKEEFKFATEEKHTYMEIGGIDTFENIVNMLNGKNIYLTIDLDV
                     LDAAVFPGTGTPEPGGVNYREFQEIFKIIKNSNINIVGCDIVELSPDYDTTGVSTVIA
                     CKILRELCLIISDKIK"
     gene            complement(19061..19261)
                     /locus_tag="KRH23_003178"
     CDS             complement(19061..19261)
                     /locus_tag="KRH23_003178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003230776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HHS5226452.1"
                     /translation="MKNGIVKWFNNEKGFGFISVEGEDDVFVHFSAIQNDGYKTLEEG
                     EKVSFDITQGNRGPQAENVNRI"
BASE COUNT         7870 a         1942 c         3427 g         6244 t
ORIGIN      
        1 aagttatata aacccccagt gccataatcg ataaaattaa actttgcgtc attacagata
       61 taatacctga cataaataaa acaccccttt gaaaatattt taaatggttt tttaaatttg
      121 gttttaaaaa atgattttga tataaaaaaa ccacacagta tatataactg tatggcaaaa
      181 attcgaataa gccacacagt ataatccatg tggctctata ttatgatgat aaaataaaaa
      241 ctttaacaac aattactata gccaacatag atacaatcct taaaaatcat aatcctaagg
      301 ggcttgtatc tatgttatga caatttgtct taacttaggt acaaacccta actaaattgg
      361 ctactaaaaa atcgtacttg tttgtttaat aaagtcttca tatttacctc tccttttaat
      421 ttaataattt tgaaaatttt gttttctgtt ttgtatagta attagtttaa tacagtaaaa
      481 aataaaagtc aactataaat tttgaaaaat tatcaaatta tcagaaaatt gagtttaaat
      541 aaaaaaattt ttacatgtag aatatagtta tattcttaat tattgttttt ttataaaaat
      601 gaaaaatata aataagtcat aaaagattat aaaaataaag agatatttag ataattagtg
      661 taaataggtt ttaaatcaac ataataactt aaattatatg gtataataaa ttaaataatt
      721 gttttaattc aaaatttttt gttattttaa attatttcaa aactcttagt tttagtgatt
      781 ttatttatga tatttatggg attaaaaaga tttcaataga tatttttggt aagtatttaa
      841 gaagtcttta actttatagg agtgataatt tatgctaata ggtacatcta aattaagcag
      901 aaatgttgat actgcatgtg tagaagaagt agggattcca atgattgtat tgatggaaaa
      961 tgcggttata tctgcaatga aaaatatgga tatagacatg tataatagtt atacagttgt
     1021 atgtggtgtt ggaaataatg gaggagatgg tcttggaata gcaagacatc taaatacata
     1081 tggaaaagaa gtaaacgtat ttttagtagg taatcttgaa aaactaagtg aatgctctaa
     1141 aataaattac aatgtacttt taaatatggg aattaatatt ataaatatta ataaaaatga
     1201 tttaagtgaa aaaaattatg gagatgaaaa tgaagtagat aaaattatta aagttgagaa
     1261 acaaaatatt ataaaaaata aaaatttaac aatttttaaa gatagagtat ctaaaagtga
     1321 tgttgtagta gatgctatat ttgggactgg attaaaacgt gatataactg gtatttttaa
     1381 agaagttatt gacatagtaa acgataatag taaaaataca tattctatag atattccttc
     1441 aggtatagat agcgataatg gaaatgtatt aggaacttgt attagagcaa acaaaacgat
     1501 tagctttgag ttttataaaa gaggttttct aaactatgac actagcacac ttataggtga
     1561 tgtagttgta gaaaagatag gtgttccaga ttttattaca agaaaatacc atgatgaaga
     1621 gttcataact gataagactt ttgtaaaaaa taatattaga agaagagata agcatggttt
     1681 taaaagtgat tttggaaaag tatctatagt tgcaggttca aaaggatttt atggtgcaag
     1741 tttcatagca actgaatctg ctgttaagag tgggagtgga cttgtaacat taattagtag
     1801 tgaagatgtg caagaaaagg tatctattag acttacagaa gcaatgactt taaattttga
     1861 agaagaaaga ttaaataaat tacttaattc tagtgatgca attggttttg gtccaggtat
     1921 gggagataat agtcaaacat ttgataaatt acttaagata gtagaaaatt ctaattgccc
     1981 aatagtatta gatgcagatg gattgaacgt tatgaaggac agatgttata agtttttaga
     2041 atggaaaaat agatttgtaa ttacacctca tttgggagaa atggccaggt tgacaggaga
     2101 ttcaattggg tatataagag aacatagagt agatgttgca aaagaatttg ctcaaaaata
     2161 taatctggtg gtgcttttaa aaggttatca aactgtcata acagatggta aaaaaacata
     2221 tataaatcct acaggaaata gctgtatggc aactggtgga atgggtgatt gtttgcttgg
     2281 aatgattact tcatttatag gtcaaggtat ggatatattg gaagctacag ttagtggagc
     2341 atatatacat ggctatatag gagataaatt gagcaaagca atgtatacgg taaatgctac
     2401 ggatttaata agtaacattt cattaacaat gaaagagttg ttggatatat aattggtgat
     2461 atttgatact actttgtaac aattttaaca aagtatgttg atataatact attaattaat
     2521 taatttattt tattgttttg taatttaaat ttatattcaa aaacattgta taaacatata
     2581 atttatatag ggttttataa ttcatatgaa aagagggtag atagtatgaa gttaatatgg
     2641 ttgatagtag cagtcttatt tggaatagca gaaatgttaa caccaagctt aacattgata
     2701 tggtttagtg taggagctgt aatacttata tttttaagta gctttataga gagtattttc
     2761 ttacaaattt taatatttgc agtaatttct atagcaatgt tagtcgtagc tactaaaaaa
     2821 atagtaaaaa aagataaagg ctataaatct aacactaatt tacaagcaat gatgtctaaa
     2881 aaaggtattg ttacagaaga gatttctcca aataacacag gtctagttgt agttgaacat
     2941 gaaacatgga cggctatttc tatagatggt gaaaagatag aaaaaggttc tacagtagaa
     3001 gtattaaaaa ttgaaggggt aaaattagtt gttaaaaaag tagacgccac agttaatgtg
     3061 acaaaccaat agaataaagg aggatttata gtatgggtac taaaattgtt ttaagtattg
     3121 tattaatagt agtagtcgta gcaataagtt taacttgtat aagagttata aaacaatcta
     3181 aagtaggtat aataatgaga cttggtaagt ttcaaaaagt ggctgaaaca ggtgtacatt
     3241 tcttaatacc atttttagat aaaatggcat atgtaattga ccttagagaa attgtaatag
     3301 attttccacc tcaaccagtt ataactaaag ataatgtaac tatgcagatt gatacagttg
     3361 tatattataa agttacagac ccagttagat atgtgtttga gatagctaat ccaatagctg
     3421 ctattgaaaa tttaacagct acaacactaa gaaatataat tggtgaactt gatttagatg
     3481 aaacattaac atcaagagat ataataaatg taaaaatgag aactatcctt gatgaagcaa
     3541 cagataaatg gggtataaaa gtaaatagag tagagttaaa aaatataatg cctcctcagg
     3601 atattcaagt tgcaatggaa aaacaaatga gagcagaaag agaaagaaga gaggcaatac
     3661 ttcaagcaga aggtaataag tcagctgcaa tacttcaagc agaaggtgaa aaacaatctg
     3721 caatattaac agcagaagcc aaaaaagaat ctatggtacg tgtagcagaa ggtgaaaaag
     3781 aatctgctat attagtggca gaaggtgaag ctgaagctat aagacagaca gctattgcta
     3841 aggcacaagg tgaagctgaa atgataaaaa gaactcaaat ggcaacagca gaaggtttaa
     3901 aattagtttt ttcagcaatg aaagaggctg atatagacaa taatattcta gcattaaaat
     3961 ctatggaagc tcttgaaaaa atggctgaag gtaagtcaac aaaactggtt ttaccttcag
     4021 aagcagttaa tttcctagga acattcaaag gaataaagga agttatgagt gatgataaca
     4081 aagaagtact tgatataaaa gaagttttaa atgataatga atcattaaaa aaataaaaga
     4141 gttttgttat cataggaagg atatggaaat taaaggtcga attaattaaa tatagcacaa
     4201 aaatgcacgt tgaaaagaag aggacttata aatttttaag tcttcttctt tgtttttatt
     4261 agaaagatga aattataaaa ataaattaac agaatcttta tacaatttat cctttactaa
     4321 tgtaaaaagt gttatataat ataatataaa acatatagca aataagcatg gttttagtta
     4381 gtctatttat attattaata tatatttata aaaatataaa cattaatact aagaaaacta
     4441 ataaataatt taaaagttta tatccttttg tttaaattat agacaaagaa gtatcaatta
     4501 aaaaataaag ttgattaata attacttgat tttctttgga taattattta acaaatatta
     4561 gattatattt tgctattacg aatttaacaa attaaaaaat aagcatgttt atatgacaca
     4621 agggatttat aaaaaatgtt tttatattta taaaataaaa tttgtattat tttttaaccg
     4681 ataattgaat attaataaat actatagtgc ttatggaaaa taatgtatac gtcggtaagt
     4741 ccattatggg gtatacatta tatcaattgt atagttgata ttattttatt tttattaagg
     4801 tattatttaa gcaacattta tacacgacat ttattgactg ataaagttta taaaagtaaa
     4861 aatgcaatta taaatattaa ttactagatg aggggagtgt cattaaatga aaaaagagat
     4921 gttagctatg attttggcag gagggcaagg ttcaagatta ggtgttttta caaaaagaat
     4981 tgccaaacca gctgtatcat ttggaggtaa gtatagaatt atagattttg tgttaagcaa
     5041 ttgttcaaac tctggtattg atactgtagg tgttttaact caatatagac cgttgatatt
     5101 aaattcacat ataggcatgg gaagtcattg ggatttggac agaataaatg gtggtgtcta
     5161 tgttttacaa ccatttatga atgaaaaaga aggaaattgg tataatggta cagcacatgc
     5221 gatatatcaa aatatggact ttgtagatac ctataatcca gaatatgtat tgatattatc
     5281 tggtgaccat atatacaaga tggattatag caaaatgtta aaatttcata aggaaaaagg
     5341 ctctaaagct acaatagcag tgattgaagt tccttgggat gaagcttcaa gatttgggat
     5401 aatgaataca aatgaagatt caagtatcta tgaatttgaa gaaaaaccaa gtgaacctaa
     5461 gagcaatttg gcatctatgg gagtatacat atttgattgg aaaatgttga gaaattattt
     5521 taaggaagca gaaaaaaatc cagaaataaa ttatgatgat tttggaaaaa atttaatacc
     5581 taaaatgtta gaagataatg ttggaatgta tgcttatcca tttaaaggat actggagaga
     5641 tgtaggaact atacaaagtc tatgggatgc taatatggat ataataaaat ctccagaaac
     5701 acttgattta gcagacccta agtggaagat atatacaaat actatggcaa tgcctccaca
     5761 atatataggt aaaaatgcaa atgttcatag atcaatgata gctgatggtt gtagaatttt
     5821 aggtgaagta ggtaactctg tattatcaca tggagttgtt gttggtaaag gaagtaaagt
     5881 aattgattca gtaataatgc caaatgttgt aataggtgaa aatgtaacta tagaaaaagc
     5941 tatgataggt gagtgtgcaa ctataaatga taatgttcag ataaagaatg taaataatga
     6001 aataaatgta gtttctgagt atgaaaatat cgaacctaga tgcgtattaa tagaaggagg
     6061 tctttaagat gagaaatgaa tgtttaggga taataaattt aaacaaaaaa ggagacccag
     6121 caataaacaa acttaactat ggaagaccaa tagcatctac accaatagct ggaagatata
     6181 gaataataga ctttgcttta tctaatatga taaattcagg aatcactaaa gttggaatat
     6241 tcgcaaaaga aaaatacaga tcattaacag accatatagg tagtggtaaa gattgggatt
     6301 taagtagaaa aaaaggtggc ctatcaattt ttagtccaga aaacactaag tatagaaata
     6361 cttactcaca tagagaaggt gatatatata ctatcttagc taatctagat tatatagaaa
     6421 agagtgaaga agaatatatt ttaatagctc caagctatat gctatgcaat ttaaattatt
     6481 ctcaagcatt ggaataccat aaaaaatctc ataatgatat aactataata tataaaaatg
     6541 taaataatgc aaataaagat tttgctggta acttaactct aaatttagat agtaacaata
     6601 gggtaataaa tgtaggaaat aatttaggta agttccctag agcaaacata tgtatggaga
     6661 catatattat gaagcgtgaa gattttgttg aatgtatata taacattgta aataaaggca
     6721 attattgtta tttagaagaa tttattattg aagaagcaga aaacatgaaa ataggagcct
     6781 atgaatatac aggatatcta aaatgtgtaa attctgttga atcatatttt gaaatgagca
     6841 aagatttatt aaatttagaa gttgcagatg aattattata ttctgaaaga aagatattta
     6901 caaaagaaaa gaatgaatca cctacaattt atacagatag tgctaaagta gaaaatagct
     6961 ttatagcatc tggttgttta atagaaggta ctgtaaaaga tagtatcata tttagaaagg
     7021 taaatgttga aaaaggaaca gttatagaga actcaatagt aatgcaaaat tgtgtaataa
     7081 agtcaaatgc aaaactatat aatgcaatat tagataaaaa tacgagtgta tcaaatggga
     7141 aagaattaag aggagatgaa aaatatcctc ttgtagtgga aaagaataca aatatataaa
     7201 taaatttttt agaaggggga gtgactaatg aaggtttttt atgtaacagc agagtgttgg
     7261 ccctttgcaa aaactggagg attaggagat gtttcttatg cattgcctaa agaattaaaa
     7321 aaagaaggtg tagatgtaag ggtaataatg cccaaatatt caactatacc aagttattta
     7381 aaagatcaac taaaagaaat agctgtgttt agtgtacgtg ttggatggag aaatcaatac
     7441 tgtggtcttt tagaaatgga attagatggt gtaaaatttt actttataga taatgaattt
     7501 tattttagaa gagaagatga aagaaagagt atctatggat atggagatga tgcagaaaga
     7561 tatactttct ttacagatgc agttttagaa gctataagta gaattgattt ttatccagat
     7621 gtaatacata taaatgattg gcatacaggg atgttaccat taattctaaa agaaagatat
     7681 gcaacccttg aggggtataa aaatataaaa actatgtata ctatacataa tctccaatat
     7741 caaggtgtat ttgataagca tgttttatat gatatattgg atttaccaca aaaatacttt
     7801 gataatggag atatagagta ttatggctca ataaatttta tgaaagctgg tataaatttt
     7861 gcagataaaa ttataactgt tagccctact tatgcaaatg aaatacaaac atctttttat
     7921 ggcgaacaat tagatggatt acttagaaaa gagtcaggaa aattaaaagg tatattaaat
     7981 ggtatagatt atgatttaaa tgaccctgca aaagataaag atatatttgt tcattatgat
     8041 gtagactcaa ttgacaaaaa agtagaaaat aaattgagat tacaagatat attgggacta
     8101 aaaaaagatt catctattcc gttgataggt atagtttcga gattagtttc tcaaaaagga
     8161 tttgatttaa tagcatacat gatgccagaa cttatgagag aagatttaca gattgtcgtt
     8221 ttaggaactg gagaacatca atatcaatca atgttcaact attacgattc taatttttca
     8281 gataaagtat cagctagaat tacttttaat gcatcattgg ctcaacagat atatgctgca
     8341 agtgatatgt tcttaatgcc atcattattt gagccttgtg gtataggtca aatgttagct
     8401 atgagatatg gttctttacc aatagttaga gagactggag ggcttagaga tacagtaaca
     8461 ccttataata aatttactgg agaaggcaat ggatttagtt ttaaaaatta caatgctcat
     8521 gagatgtttt tctgtttgaa aaatgcaatc aaagtattta aggacaaaga aaaatggatt
     8581 aaattagttg aaaatgcaat gaaaacagat aatagttgga aaaaatcagc taaggagtat
     8641 atagaaacat atagagacat atgtgattaa aggagtggtt tttttggtaa caataagcaa
     8701 aaagaaattc aagcaaaaat ttgaagtaaa aatgtatagc ttatatgcac aatctatcaa
     8761 ggaagctact gatgaacaat tgttaaatgt attatgtagt ctattgaaag atgagatagc
     8821 aaaaaaatgg gttgctacaa agttagataa gaaaaaagaa gtttattatt ttagtttaga
     8881 atttttaata gggagacagt taaaatctaa tttattaaat ttaaatattg aagaagaagt
     8941 tagagaaggt ttatctgaat taggaatcaa cttggatgat ttaattgaag ctgaagtaga
     9001 cccagcctta ggaaatggtg gacttggtag attagcagct tgctttttag attctatggc
     9061 atctttgaac ataagtggtc aaggatatgg aataaggtat aaatatggtc tgtttgaaca
     9121 aaaatttgta aatggttatc aggtagaagt gcctgataac tggcttacag aaggacgata
     9181 tgcatgggaa actgtaagac caaatgaagc aacaatggtg aagtttggtg gtgaggtaga
     9241 attaatcaag gaaggtagtc atttaaaagt aattcataaa aactaccttc ctgtaatggc
     9301 aatgccttat gatataccaa taatcggata ccaaaaccaa tgtataaata ctttaagatt
     9361 gtttaagagt gaaataccaa agagagattt tggtgaactt acctcaaatg ctctaaatta
     9421 ttctggtagc tatgaagagg ctttaaaaca taagtattat actgaggaaa tatcacaggt
     9481 attatatcct gatgattcaa actatgcagg taagttgttg aggttgaaac aagaatactt
     9541 ttttgtaagt gcagggatac aagatataat aagaaaatat aaaaagaaca aattaaatat
     9601 taataattta ttcgataagg tagcaattca tataaatgat acacatccta ccttatgcat
     9661 accagaactt atgagaattt tgcttgatga agaaaattta tcttgggatg aagcatggga
     9721 aataactaaa aaaacagtgt cctatactaa tcatactata atgtcagaag caatggaaaa
     9781 atggcctgta agtatgatga aagaactatt accaagaatt tatatgataa tagaagaaat
     9841 aaatagaaga tatgtagagg aattaaataa taaaggatat gaccaagata gaataaaaag
     9901 aatgagtata atagactgtg acaatatcaa tatggcaaac ttatgtattg tcacaagtca
     9961 tagtgtaaat ggagttgcta agcttcatac tcatattctt gaaacagagg tattaaaaga
    10021 tttctatcaa gatgaaccaa ataaatttaa taataagact aatggaattg cacataggcg
    10081 atggcttata agttcaaatc ctcaacttag caatttaatt acagatttaa ttggtgattc
    10141 atggaagaaa gatacattac aattaaaaaa tattgaaaaa tttaaaaatg attcctctgt
    10201 tttacaaaga cttgatgata taaaatacaa taataaagca aatctagcaa agtttataaa
    10261 agataaatac gatttaaatg tagacccaag ttcgatattt gatgttcaag ttaagagatt
    10321 gcatgcgtat aaaagacagt tactgaatat atttaatgta cttcatatgt atcatgaatt
    10381 acttgataat cctaatttga atcttgaccc aagaactttt atatttggcg caaaagcagc
    10441 accaggatat tatttggcta aatgtataat taaatttata aattctgttg caagtactat
    10501 aaataatgat gttagagtaa aggacaagtt aaaagtagta tttttagaga attatggagt
    10561 atcattagca gaaataataa taccagcagc aaatgttagt gagcaaattt caactacaac
    10621 taaggaagca tctggaacaa gtaatatgaa gtttatgatg aatggtgcta taactttggc
    10681 tacacttgac ggtgcaaatg tagagatatg tgaacaggtt ggtaaagaaa atatgttttt
    10741 atttggactt agtgcagaac aagtactaaa ttataataaa tatggtggat attcttcact
    10801 tgacctatat cattctaata tggatataaa aagggtagta gatgatttaa taaatggatt
    10861 tattcctaat cttggcgaag aaggaagaag tatttataat tcactcacta cttacaatga
    10921 tgagtatttt gtattgagag attttgaaaa ttatggtcaa gctcaagcag atataaacag
    10981 gttatataga gataaagaaa aatggaataa aatgtcttta gttaatatag ctaactctgg
    11041 atttttttct tctgatagaa caatttctga gtatgcaaaa gacatttggt ttaaaagggt
    11101 gtgattaaat gcaaagtgta atagaatata actcttggga taaaaatttt aaggctccgt
    11161 ttggagcttt aaaatttgat gaggaattga ccatttgtgt taaagtaaat gagggataca
    11221 atatcaagtc tatttcccta gaaataaata gagaagaaga aatgagaaca ataactttaa
    11281 atgaagaatt agataatgat aaacttggaa agtgcttttg tggtaagatt gaaaagtttg
    11341 atggtacagg tgtttatttt tattacttta aagttgatgt tgaaatggat ggtcagataa
    11401 agactttatt ttatggaaaa aacagagata atggatattc ttgtgaatat aattatagtg
    11461 atattaataa atatcaaatc actgtttata aagattttaa agtaccaaca tggtacaaag
    11521 aaggaatact ttatcatata tttgtagata gattcaataa tggaaatcgt agtggtaagg
    11581 ttgataatcc taaaaaaaat agtttcatat atggaaattg ggaagataca cctatgtaca
    11641 taaaggatag tcaaggggat gttataagat gggatttcca tggtggaaat ttaagaggga
    11701 taatcaataa acttggatat ttaaaaaaat taggtgtaag tatactatat ctaagcccta
    11761 tatttgaagc ctctagtaat cataagtatg atacaggtga ctataaaaaa attgacccaa
    11821 tgtttgggga tgaagataca tttaaagaac ttattgataa agcaaaagaa aaaggtatat
    11881 caatagtatt agatggagtt tttagtcata ctggagcaga tagtaaatat tttaatatgt
    11941 atggaaacta taatagttta ggggcatatc aatctaaaga atctccatat tattcatggt
    12001 atatgtttga agaatttcct caaaaatata aaagttggtg ggatgttaag acattgccga
    12061 atataaatga attagaacat agctatatgg attatataat atatgacaat gatagcgtta
    12121 taaataaatg ggtaaatatg ggtattaagg gctggagact agatgttgca gacgaattac
    12181 caactaagtt tataagagag ttaaaaaagg aattaaaaac ggcagatgat gactcaattc
    12241 ttataggtga agtatgggaa gatgcatcaa ataagattag ctatggtcag agaagaagtt
    12301 atttattagg tgaagaatta gattctgtta tgggttatcc ttttagaaat aacatgtttt
    12361 ctttcttaaa aggagaaatt aattcatatg aactttgtaa tagatatatg cagattaaag
    12421 aaaattatcc aaaagaatca tttaggtcta atttaaattt aattggaaca catgatgtta
    12481 caagagctaa aacggaatta aatgatgatg tagatttagt gaagcttgct gtagctatac
    12541 agatgacatt tgaaggagta ccatatatat attatggaga tgaagcaggt ctttgtggag
    12601 gtgttgaccc agataataga agaacttatc catggaaaaa tgaagacgaa gatatgctta
    12661 atttttatag agatgttata aaaattagaa ataagaataa acttttaagt tctggaaata
    12721 cagaatttat atatactaat aatgattctg tattttcttt tattagagtt aatgaaaata
    12781 atgatagaat attaatttta gtaaatagaa gtgaaaatgt ggaaagtata tcattatgta
    12841 tagagagtag ttttattgag gaaataccta taaagtatag tcttaaaaat gcaaatagta
    12901 ctatacaaat tgaaaataat gagttgaaag tagatttaga ctctaaatca tttagaattt
    12961 ttagagtaaa ttaaatatct ttttttagaa aaataaatag aaaataaggt gaatgtggaa
    13021 agagttttgt tttatcaaaa ctttttctac tttttttgta taaattatca taagaatttt
    13081 agtatttcaa aatattacaa agaagtataa aaaatatcat aattgtgata ttatataaat
    13141 tagtaagata aaactgaact ctctaccaaa gttgtaggga gatttaactt ttataatctt
    13201 aatatggagg aacgtcttat gaaggtagat ccacttacaa ctcaagtata tgactatata
    13261 tcaaagaaaa tccaaaatgg agaatatgaa gctaatcaga gaattactga atctgagatt
    13321 tgtaaatcta tcggagttag tagaacacca gcgagagaag cattaactag gttagcaggt
    13381 gaaaatttac tagaaaaaat acctaataag ggatttgtag taaaagaatt tcaggaaaag
    13441 gagaaattag acacctattc cgtaattgga gtattggatg cgttagccgg ttcttcagca
    13501 ttacaaaatt taactgaatc agacctagta aaaatggaag aattaacaga aatgatggcg
    13561 gtctctataa agtataaaaa ttacaatagc tatttaaaat taagtaatga atttcacgat
    13621 atatacataa ctaaatcaga taatcaggtg ttagtaaatc tattgaactc tttaagatat
    13681 aattttatgt caaagtcata tactagtgat aatgaagatg agttatataa aatgttgaca
    13741 tacagcaata atcaacatat tgaagtagta aaatctatga gggagaatga tttagaaaat
    13801 gttgaaagaa ttttgagaga acattggaaa acgataccta tggaagagat gaaaaaagag
    13861 aagcttttat aaagtttctc tttatttttt ataccatttt atcactattt ttttgaatta
    13921 ttaagtagaa aataataatt aatttaaact tgaggaggaa aactaatatg tatccaaata
    13981 aagaaattgc aatagaagag ttagaagtgg ctggcaaaat gaatcccggt ccatggataa
    14041 aacattctta caatgttgct aatgtagcta aattgattgc agagcaatgt gaaaatttga
    14101 atagtgaaaa ggcctttgta tgtggattat tacatgacat tggaagaaga actggtattt
    14161 cttctgtaag gcatattatt gatggatatg attatgttat ttctaaggga tgggatgaag
    14221 tggcgagggt atgtttgaca cattcttttc ctgttaagga tatagaagct gatattggaa
    14281 ataaagatat tagtaaagaa cagtatgatt ttatcaatca ctatttaaac aaccttgaat
    14341 ataacgatta tgataagttg attattcttt gtgatgcatt agcagatgca aatgggtttt
    14401 gtattttaga aaaaagattt gttgatacaa cacgaagata tggaatatat ccattttcag
    14461 ttgaacgatg gaataagact tatgagtata aagaatattt cgagaaaata atcaacaagt
    14521 ctatatatac attgttaccc aatattgaaa aatctatata ttattaaatc ctaagttaat
    14581 aatttaatat ccagtatcac cagcagttgg tcattatgat tgactgcttt tattatgctt
    14641 atattaaaaa aatacactat ggtttgtgta tatcaaagtt atatggaatg aaaagagaat
    14701 ttattttatc aattaaaaaa tttaataaat tttatattaa aattaaaata caaaaatagg
    14761 aaaattattt agtccaacta aaccaagaat tttgatatgt gaaataagaa taatataaaa
    14821 gtttagtaat aaaatactta taaattaaaa atagtaaact caaaagctta ctaaaactca
    14881 aaaaagtaaa aaaaccaaaa taataaaaaa taagaaagtt tataaatact aagttttaaa
    14941 aaaattaata taaacaacaa aaaattaaaa agtttataaa tattgatata gctaatgtat
    15001 atgtttttga gtaacttcaa aaaaacactt gtaaaaatgc tgagatgtta atataataaa
    15061 tatcatgagt ttaataaaag taaaaataaa aaatagaaat aataaataat aaatattaaa
    15121 aatatttgaa tatagagagg agatgaattt gaaatcatgg atagcgagtt tgcaaatgca
    15181 gttgaattaa gctatgagtg tgctccatta ttagagtcgt taaaggaata ctcagagaaa
    15241 gatatagctt gttttgatgt gcctggacat gtaaaaaata gaggtgtagc tatattaaat
    15301 aaatatctag gtgaaagtct catgaaaatg gatataaatt catcaccaac tatggataat
    15361 gtatctgcgc caaatgggat tataaaaaat gcacaagatt tgctagcaca agcatatatg
    15421 gctgatgagg cattctttat aacgaatggc acaactcaag caatacatgc aatgattttg
    15481 agtgttataa aaccaggtga aaaagtatta cttccaagaa atatacataa atcagtaata
    15541 aatgcgttaa tactttgtgg aggaatacca atatttatac aaccagaatt tgatgaaaaa
    15601 ctaggtataa gtttaaatat tactcttgaa aaagttagaa cagagataga aaaagattgt
    15661 aatataaaag cattattttt ccttaatcca acttactatg gagtttgtgc agaccttgag
    15721 agtattatag aactatgcca taaaaataat gttttagtgt tagttgatga agctcatggt
    15781 gcacattttc catttcattt agatttacct ccttctgcaa taagtttggg agctgacatg
    15841 gtagctgtaa gtatacataa aactggagga gcattgacac aatcttcagc actcttattg
    15901 aatagagata atgtaagttt tgaaaaggtt cttcaatcaa tcaatatgct acaatcaaca
    15961 tcagcgtctt atttgcttat ggcaagtata gatggtgcta gagttaatct agttgagaat
    16021 ggtgaaaagc aattgtcaaa agcattaaat ctatctaggt atgcaaaatc taaattaaac
    16081 aaaattgatg gaataaaagt tttatctata gaaatattga aacaaaaagg tgttaaattt
    16141 atagatgaaa caaaattgtg tataaatgta aaagaattaa atttgactgg atttgaagta
    16201 tacgatttat tatataaaaa tttttcaatt caagtagaat tgggagattc atataatata
    16261 ctggcacttg tgtccattgg aacaaataaa tcagatatag atagattagt aaaagcactt
    16321 tctataattg caaagattta tagaaaagaa tcaacattaa atgaatttaa tatggttcaa
    16381 ataaatccaa ttattaaact taatccaaga gaagcttttt atgcaccaaa ggaaagtgta
    16441 gaaatcaatt catgtataga tagaatttgt ggagaatcaa taatggcata tccaccaggt
    16501 ataccgatta ttgctccagg agaattgata acagaagaaa ttatggagta tattattttc
    16561 ttaaaaaata gcaatgcgta tcttacagat gtacaagata aaaacttaga tagaatacta
    16621 gtaataaaat aaattacttt attttgcaag ggcaagtgtt tgttaagtag agtttatcaa
    16681 atagaactta ttaaaagtat aaaggagttg gggttgaaat gaaatttgaa acactaggaa
    16741 gacatatact agtagaatac tataattgtg atgaaaacgt acttaaagac ccacgtctta
    16801 tagaaaattt tatgaatgat tcagcattaa atgcaaaagc gacaattgtg gattctgtat
    16861 tccaccattt taatccttgg ggggtttcag gagctgttat aattgctgaa tctcatttga
    16921 caatacatac atggcctgaa tatggttatg cagcagcgga tttttttact tgtggtgata
    16981 tagacccatg gaaaagtttt gaattattag agcaactttt aaagtctgaa agaagcgagt
    17041 ctacagaaat tccaagaggc ttaactacaa aaattaaaaa atattcaaaa aaagatttag
    17101 gtaagattac tcataaacca gaagcagtat aaaacataca agagaaagtg aggattatta
    17161 tatggaactt tggtatacag aagaatggac agaaaatgta agattttcta taaaagtaaa
    17221 taaacatcta tttgaaggaa agtctcaatt tcaaaggata gatgtgtttg atagtgatga
    17281 atttggaaaa tttctaacaa tagatggatt aatgatggta acatataaag atgaatttat
    17341 atatcatgag atgataactc atgttcctat ggctacaaat ttaaacataa agaaagtatt
    17401 agtcataggt ggaggtgatg gaggtacagt aagagaatta agccgttatc ctcaaataga
    17461 aaagattgac atggttgaaa tagataaaat ggttgtagat gtatctaaag agtatatgga
    17521 tatatgctca tgtaaattag atgataaaag agtgagttta tattttgaag atggtgttaa
    17581 ttttgttaag tgtgcacatg ataaatcata tgacctgata atagtagatt caactgaccc
    17641 aataggacca ggtgaagggc ttttctcaac tgatttttat aaggattgtt atagaatact
    17701 gactgatgat ggaattttag taaatcaaag tgaaagcccg tattttgact ttaatgctaa
    17761 agagatgaaa agagctaata aaaagttaaa acagatattt ccaatatcag aagtttatca
    17821 agcacatata ccaacatatc catctggtca ctggttgttt ggatttgctt caaaaaaact
    17881 taatccagta aaaaatcaag atagaaatgg atgggagaaa ttaagtttaa aaactaaata
    17941 ttataatagt gatatacatt taggttcgtt tatgttacct caatacgtga aggagatgct
    18001 agatgaagaa taatttctat catatgaaca cttttatgag tatggacaaa aattatgaag
    18061 aatctaatct tatagtattt ggtgttggat ttgatggaac tacttctaac agacctgggg
    18121 ctagatttgc aagtagctct atgagaaaag aattttacgg tcttgagaca tatagtcctt
    18181 ttttagattt ggatttagag gattataata tatgtgatta tggagattta gaaattagtg
    18241 ttggaagtac agaacaagtc ttaaaagaaa tctatcaaga gacatataag attgttagag
    18301 attcaaaggt accctttatg attggaggag agcatttagt tacattacca gcctttaaag
    18361 cagtacatga aaagtacaat gatatatatg taattcattt tgatgcccat actgacttga
    18421 gggaagaata taataatagt aaaaattctc atgcaacagt aattaaaaga atatgggata
    18481 ttgtaggtga taataaaata tttcaatttg gtataaggtc tgggacaaaa gaagaattta
    18541 aatttgctac agaagaaaaa cacacataca tggaaatagg aggaatagat acgtttgaaa
    18601 atatagttaa tatgctaaat ggaaagaata tttatctaac tatagattta gatgtattgg
    18661 atgcagctgt gtttccagga acaggtacac cagaacctgg tggtgtaaat tatagagagt
    18721 ttcaagagat ttttaagatt ataaaaaact ctaatataaa tatagttggt tgtgacattg
    18781 tagagttaag ccctgattac gatacaacag gtgtatcgac agttatagct tgtaaaatct
    18841 taagagagtt atgcttaata atatctgata aaattaaata gagtatttta tataaatagt
    18901 atatattata atataagaag ttattttaaa aaagttagtt taagtttgac gcttttctaa
    18961 agtaacttct tatttttgta attaaaaata aatataataa acaacaaaaa agagccctcg
    19021 atagctcctt ttctaaaata tatatattta aattaaataa ttatattcta tttacgtttt
    19081 cagcttgagg tcctctatta ccttgagtta tatcaaagct aaccttttcg ccttcttcta
    19141 aagttttgta tccatcattt tgtatagctg agaaatgtac gaaaacatca tcttctccct
    19201 ctacagatat gaacccaaat cctttttcat tgttaaacca ttttactatt ccgtttttca
    19261 ttataagaaa acctccgcat tattaaaaaa tacaaactaa aaaaataagt ctgttctatt
    19321 aatataacat aaattttaaa taaaagcaaa taaaattttt aaaaaaatta attactttta
    19381 gaatttaata aaaattgtta aattatacag tgagaagtat tgtaaaattt gacgaaaatg
    19441 taaatgtaga taataaattt aatatcaaaa aatgtaacaa aaa
//
LOCUS       DAEORM030000067        18784 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.067, whole genome shotgun sequence.
ACCESSION   DAEORM030000067 DAEORM030000000
VERSION     DAEORM030000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18784)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18784)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 18784)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18784
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.067"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            complement(<1..601)
                     /gene="yqeC"
                     /locus_tag="KRH23_003179"
     CDS             complement(<1..601)
                     /gene="yqeC"
                     /locus_tag="KRH23_003179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="selenium cofactor biosynthesis protein YqeC"
                     /protein_id="HHS5226453.1"
                     /translation="MELSNIIEKNEIITVVGAGGKTSFINYFANFYRDKLKVLLTTTT
                     KIYVPNDYDNIIITIDGTVIPSICHGITVCGSYINNENKLVSIDSSILDEIVDQFDLV
                     LIEGDGSKRKKLKGWNAKEPVVYHKTTKTIGILDITSFGMNINEENIHRVEIFKKIAN
                     LDTSSINSSSTVSIENLKNIVLNPNGLFKNYSGKRVLFIN"
     gene            complement(784..2061)
                     /locus_tag="KRH23_003180"
     CDS             complement(784..2061)
                     /locus_tag="KRH23_003180"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0032196 - transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-guided endonuclease InsQ/TnpB family
                     protein"
                     /protein_id="HHS5226454.1"
                     /translation="MSNRIKNIHYGTQRQQLKNLTKKEYQALREMCFLAKNLYNVGTY
                     NVRQHYFNQGEHLNYEANYHVCKENENYKLLNSNIAQQILKEVDSSFRSFFGLIKLAK
                     EGKYDFRGIKSPKYLDKEGFFSIIIGQIRIKEDGILNVPMSPAFKKLYGKVSIKVPQN
                     ILEKKIKEIRIIPKHKARFFEIQYCYEIPKSEEVSNQKNALAIDLGLENLCTCVTNLG
                     DSFIIDGKRLKSVNQWANKQNDKIEALKLKKNITAITRKQFKVWNKRNNQVKDYVNKT
                     CFYIIDYCVKNNIGNLIVGYNAKLEKSDNMERKIYRNFIRIPFGEIKGKLEYLCKIKN
                     INFIRQEESYTSKSDFFADDFLPDINVDNIKKYDFKGERITRGQYKSSVGIIINADVN
                     ASLNILKKSQVVNLSNLQNNPQILKQPQRVRIS"
     gene            complement(2200..4506)
                     /locus_tag="KRH23_003181"
     CDS             complement(2200..4506)
                     /locus_tag="KRH23_003181"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043546 - molybdopterin cofactor binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine dehydrogenase family protein
                     molybdopterin-binding subunit"
                     /protein_id="HHS5226455.1"
                     /translation="MINKGIRKIDSTAIVTGKPLYTEDLIMHKDVLTLKLLRSPHAHA
                     KIKNIDTSKAEKIPGVVGIYTYKDVPQVRYCVPGQTEPEASPYDRVLLEDTVRFIGDE
                     VALVAAEDEKTALKALKMIKVDYEVLKPVFDAREAEGNEVVIHPEKDIVEPYPFGLDA
                     KNNIVSKEFFEFGDVEAKLKESDFVVESSYKTQSQSHCMMETHRSYSYKDINDRIVVV
                     SSLQSPHNVKRILRKVLGIPSSKIRVIKPRIGGGFGGKNIAATDIFTAFVTMKTGRPA
                     KFVFTRSETFVGSNSRHEMFFDVKVGADKEGNLKAIELKSLNNTGAYGGNGVSVSSES
                     GHNTLPIYNDIDAVRFNARTVYTNRLPAGALRGYGATQGIFAIDSAIDELAHKIGMDP
                     LEFRIKNIIDRYTNGKAAEDEILSCELRQCIEKGKKLINWDDKYPCKDIGNNKVRAVG
                     MAVANHGSGIPRVDMATVTIRMDEDGTYKLLSGLADLGQGADTIQAQIAAEALNTTVD
                     RISIYTGDSDLCPYDTGAFASCTTTVTGNATIKTANKLKDILLSVAESKLGFKKEDLE
                     LGKDRVFVKNDNSKFVLLEELGRESVGGIGFASDDVPVVLEATESFGMLKKIKPFIAG
                     FAEIELDKNTGEYKVINFACVPDCGTVINPTLARIQVEGGVMMGIGFAMYEDPVFDKD
                     GRLLTDSFLQYKVPTKKEVGNILVDFAENFDPGGPYGAKSLGEIVIHTPAPAIANAIF
                     NATGVRLRELPMTFEKVYMGMKNNNKQL"
     gene            complement(4499..5293)
                     /locus_tag="KRH23_003182"
     CDS             complement(4499..5293)
                     /locus_tag="KRH23_003182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD binding domain-containing protein"
                     /protein_id="HHS5226456.1"
                     /translation="MVTIKEYSVPQSLEEAYKILISKKNNVILGGCGFIKLSNKNIGT
                     AIDLKDINLNYIKEDEKNILIGADTSLRSLEIDKTIKNYCSGILSSAVSNIVGVQFRQ
                     GARIGASVFSKYGFSDLIPALLVVGAKVRLYNKGILELSEFLDSELSRDILVEVILPK
                     KDAIAVFDSIRKCTGDFSVLNSAMLKENDTYKIAIGARPQKARLALEASNILNKEKDI
                     DKASIVASKELTYGSNMRASKEYRKDMASALVKRMYNAIEEGMYND"
     gene            complement(5400..6758)
                     /locus_tag="KRH23_003183"
     CDS             complement(5400..6758)
                     /locus_tag="KRH23_003183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015851 - nucleobase transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-xanthine permease family protein"
                     /protein_id="HHS5226457.1"
                     /translation="MKAKSTSKFELDGIPPLKEAIPLGLQHLMAMVIGSCLPAILIAN
                     AAGLNHKMSTLLIQAALVFAGLSTLLQLYPIPLFKGFKLGGGIPVIMGATAMFIGAGV
                     SVASKYGLPVLFGSQIIAGIVIIIIGFGLKKIRFIFTPAVSGTIVACMGLGLFPIAIK
                     NLAGGMGNETFGNPINFIVGISVSLMILGLNKYGKGLFKDASILVSIIFGYILSLILG
                     IVNFSSIQEFTLVALPKPLAFGLDIRLEVVVMFSIIYLVEIADIMGACTLSAVGGLNR
                     QVTDEELSSAVLGNGVLSTIGALFSATPMGMFGQNSAIVSNTKVVSKFVLAIGGIGLF
                     LAGISPLLANLIRTIPPCVVGGATLVIFSTLTTSGLRLVSMDGFNQENSMILGLSMAS
                     GIGFMVAPQVLEKFPKFIETLLADSSVVSGAMVAIIIQALYMVKFPGNKSDKVEDKNK
                     SL"
     gene            complement(8105..8980)
                     /locus_tag="KRH23_003184"
     CDS             complement(8105..8980)
                     /locus_tag="KRH23_003184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226458.1"
                     /translation="MQVQEKILELLYTINEDVVSIKNDMSEVKQEINVLKEDMSEVKQ
                     EMIVMKEDMSEVRQEINIMKEDISEVRQEMTVMKEDMSEVKQEINVLKEDMSEVKQEI
                     NVLKEDMSEVRQEINIMKEDMSEVRQEMTVMKEDTSEVKQEINVMKKDMSEVRQEITV
                     MKEDVSEVKSEVNFMQNKINNINEDMNGIKDEVSIVNEKLYGIEIKIDSLECEDKSMK
                     EIQIEQNNILGSLLHNSEINKATHDNIEHNIAYIKGDTNSIKEDIAEIRRDLNLVELA
                     TSKNWSDIVKLKSVK"
     gene            complement(9216..10301)
                     /locus_tag="KRH23_003185"
     CDS             complement(9216..10301)
                     /locus_tag="KRH23_003185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HHS5226459.1"
                     /translation="MYNFLGKELKSPLIIGSGPLTYSAAGCKILSDAGAGAVVTKTIR
                     KERAINPAPHMVRNTANALLNNEKWTDFEPEQWIDFEIPQMKRDGTVCIASIGHTIEE
                     SSELVEKVANAGADFIELVSYDYRDLIPMLKDAKERVNIPVIVKLPPMIDEIGDFAKK
                     LEEAGADAITACDSVGPAFRIDIETGQPLLGGNGIGYLSGETIKPITLQRIYEIKKQV
                     NIPIIGLGGCVSGDDALEMIMAGADFVGICSVVILKGAQVISKIHDDLKSNLNRLGYN
                     TIENACGIVHNHMGDVNERLSFEFTYDEEKCTKCKMCERVCAYQARKLNDKMELNEEE
                     CRYCGLCISVCKPKALGRKISCSELNV"
     gene            complement(10337..11650)
                     /locus_tag="KRH23_003186"
     CDS             complement(10337..11650)
                     /locus_tag="KRH23_003186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HHS5226460.1"
                     /translation="MIAIKSKYLISSADEIYTNSAVVVENDIIKDILPNEEVEIKYKN
                     IEEIIDKSDAIIMPGFVNGHMHQYGVLSRGIPANVHFTDFEGFLNDYWWPFIENRIGL
                     KEVKATTKASAIELIESGVVAFCDTLEAPNTEEGTLIEQGKILEEIGMKAILSLESCE
                     RISFENGLRCLDENSNLIKWSRENSKLINGIMCTHTSFTCSDRFIKKAKEDAKKLNAP
                     MQFHLCESIYEPNYAEKHFGKKAVDYYNDLDILDETVLASQCVKVNDEEIDILKEKGV
                     KVVHMPLSNCEVGGGFSPVPKMIKKGIKVALGTDGYINDFFEVMRGAFLMHKSVEEDA
                     SVMPANLVFRMATEHGAYVLGLQNSGKIAVGNKADIIVMEDEFKTPVTLDNIFDQIVV
                     QGKKEFISNVYIDGRHILKEKQLVDLDKKAIVKEMKEVACEFWKF"
     gene            complement(11651..13942)
                     /locus_tag="KRH23_003187"
     CDS             complement(11651..13942)
                     /locus_tag="KRH23_003187"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043546 - molybdopterin cofactor binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine dehydrogenase family protein
                     molybdopterin-binding subunit"
                     /protein_id="HHS5226461.1"
                     /translation="MVNKEVRKIDSEAIVTGKPIYTEDLIFHKDVLTIKLLRSPHAFA
                     KIKNIDIKNALKVKGVVNIFTYKDVPNYRYSMVGESYPEASPHDQLILEDVVRYVGDE
                     VAIIAAEDERAAIKAMKLIKVEYEVMTPILDARESEGNKILIHEEDDLFCPFDFGLDA
                     TKNIVSREKMGKGDVEKEFKESDVIVEHSYMTQSQAHCMMETHRAYTYIDTNGRLVVT
                     SANQSAYHMRRQVSKALGIPLSKVRVIKPRIGGGFGGKNIAVTEIYASFVTWMTKRPA
                     KLIYTREETFAMTNTRHQMFFDIKIGADKEGNIKAIDMKALNNTGAYGDNGPSVCSES
                     GHNVLPTYNNVPAIKFDGRTVYTNLVPGGALRGYGATQGTFALDCAIDELAHKLNMDP
                     TEIKLKNIIKKQTEGGIMNFPIRSCALDECIIRGKKLIGWDEKYPVRDIGNNKVRAVG
                     MSVGTHGSGIANIDMAIVNMRMDEDGTYKLFSGSSDLGTGSDTILAQIAAKALNTSID
                     RISVYTGDTDMCPYDTGAYASCTTYVTGNATIKSAESLKQKILKVAQKKLDLPIDDLI
                     LYEDRVCYSEDVEKFVLLSELGKESVGGGNQEVLYSSESYGIQESAKPFLAGFAEIEL
                     DKTTGEFKVINYACSTDCGTVMNPALARIQVEGGVTQGIGLAMYEDPRHGSDGKLQTS
                     NLLQYKVPTKKDIGNIIVDFVDNYEPTGPYGAKSLGEIVIHTPAPAIANAIYNATGVR
                     IRELPITSEKVYMAMKKLNQGGK"
     gene            complement(13932..14726)
                     /locus_tag="KRH23_003188"
     CDS             complement(13932..14726)
                     /locus_tag="KRH23_003188"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1990204 - oxidoreductase complex
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD binding domain-containing protein"
                     /protein_id="HHS5226462.1"
                     /translation="MITIKEYVVPKSLDEAYELLISRKNNIILGGCGFLKLGSKNIGS
                     AIDLKDLALDYINETDDSILIGADTSLRTLELNKVIKNYCNGVISNAVSNIVGVQFRS
                     GARVGASVFAKYGFSDLIPSLLVVDAKVKLYKKGVMNLADFLESELEKDILIEVILPK
                     KDAIGVFDSIRKCTGDFAVLNGAMLKEGSIYKIAIGARPRRAKIAYKASEILSLENDI
                     EKAGEVSSEELSFGSNIRGSKEYRKDMAKALVVRMYNSIGGECDGK"
     gene            complement(14765..15211)
                     /locus_tag="KRH23_003189"
     CDS             complement(14765..15211)
                     /locus_tag="KRH23_003189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="(2Fe-2S)-binding protein"
                     /protein_id="HHS5226463.1"
                     /translation="MIIKCTINNKEKELSIRPDDFLADTLRENGYVSVKKGCDTGSCG
                     LCTVMVNDKAVLSCNYLTARVDGQHITTLEGVLDEAKKFGDFLADEGADQCGFCAPGF
                     IMMVLAMKRELQNPTEEEVIDYVNGNLCRCTGYKGQLRAIHKYLNT"
     gene            complement(15283..16689)
                     /locus_tag="KRH23_003190"
     CDS             complement(15283..16689)
                     /locus_tag="KRH23_003190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HHS5226464.1"
                     /translation="MMDILIKNAIIVTVNKEREVIFDGALVVKDNKIADIGNSKEIES
                     KYTDVKKIIDAKGKVLFPGFINTHNHLFQTLLKGLGDDMVLKDWLETMTFPAANYLEP
                     KDTYDAAMLGCIEGLRSGITTMVDYMYPHSKPGLCDGIIDAYKELGIRGILGRGCMNT
                     GAQFGVHPGIMQDVETVEKDVRRLFEKHHNTENGRIKIGVAPAAIWSNSQEMLEMLWR
                     VVKEYDDALFTVHISETPFDREAAKELHGQYDIDVLEKLGILGPNVLMVHCVYLTEKD
                     MELTKKYDMKVSHNTASNMYLSSGVAPVPEMLKKGITVSLGVDGAASNNSQDMLELMK
                     LTALQHKVNKCDPLAMSAEKVLELATIDGARAIGMEDEIGSLEIGKKADLLIFNPMLS
                     PKAIPMHNPVSTLVYSSSMKNIESVIVDGNIIMEGSKILTANEEKALKDAQDTAERLC
                     VRGTIKNRMEGHKWNSLY"
     gene            complement(16707..18077)
                     /gene="hydA"
                     /locus_tag="KRH23_003191"
     CDS             complement(16707..18077)
                     /gene="hydA"
                     /locus_tag="KRH23_003191"
                     /EC_number="3.5.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004157 - dihydropyrimidinase activity
                     [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropyrimidinase"
                     /protein_id="HHS5226465.1"
                     /translation="MGTILRGGTIITSDKTYISDLRIEDEKIVEIGNNLEINGDKVID
                     ATGKIVIPGGIDTHTHFDMNAGSITTADNFETGTRAAIAGGTTTILDFAEANEGENLL
                     QGVEAYHKKASGNCYCDYGFHMTITCLNKDTFNHMEKLISDGIVSFKMYMAYDGMKVD
                     DGTIYRVLKKARDLGCIVGFHCENGDLLDVLIEENIQNGNLETKYHPLTRPNIVEKES
                     VSRLADITKLSNSKSYVVHLSCRESLETVKMAREKNIDMIVETCPQYLLLEDNLYNKD
                     KFEGAKYVMSPPLRKKEDINYLWEGLSSGDIQTVGTDHCSFNFKGQKDLGIDDFSKIP
                     NGAPGVEHRLALLYTYGVLENRISVNKFVEVTSTNAAKIFGMYPKKGEIAVGSDADIV
                     ILNINKEETISYKTQKQNVDYTPYEGFKVKCKVEDVFLRGNHVVQSCNVKEHPTGQYI
                     KRKITK"
     gene            complement(18210..>18784)
                     /locus_tag="KRH23_003192"
     CDS             complement(18210..>18784)
                     /locus_tag="KRH23_003192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HHS5226466.1"
                     /translation="NVIQKIQQLVPPTHPVLGDGILVLTDIKSSPYPGASVVPDYCKA
                     TFDRRLLVGETREGVLAPIQALLDEMMKEDPELNAKVSYAVEKADCYTGNTIESERFF
                     PGWLYDEEDEFVQAAYKGLKEAGIDSEITQYSFCTNGSHYAGEAGIKTIGFGPSKENL
                     AHTIDEYIEQEQLFIGTEGYYGILKSVYGK"
BASE COUNT         5651 a         3646 c         2009 g         7478 t
ORIGIN      
        1 tattaataaa taatactctt tttccagaat aatttttaaa taatccattt ggatttaata
       61 ctatattttt taagttttca atacttactg tagaactact attaatacta cttgtatcta
      121 aatttgctat ttttttaaat atttctactc tatgtatatt ctcttcatta atattcattc
      181 caaatgatgt tatatctaat atccctatgg tttttgtagt tttatgatat actactggtt
      241 ctttagcatt ccaaccttta agtttttttc tctttgagcc atctccctct attaaaacta
      301 aatcaaattg gtctacaatt tcatccaaaa tagaggaatc aatacttact aatttatttt
      361 cattatttat ataactacca catactgtta ttccatgaca aatagatgga ataacagttc
      421 catctattgt aataattata ttgtcataat cgtttggtac atatatttta gttgttgttg
      481 taagaagaac tttcaattta tctctataaa aatttgcaaa atagtttata aacgaagttt
      541 ttcctcctgc tccaactaca gttattattt cattcttttc tattatattt gatagttcca
      601 cactttcacc tcttataacc agttttctaa tctcttaatt attatagtta gatcttttta
      661 gtaaaagtga tttttgaaat tccataaact cgaaagtaaa tagattctgt tgtaaacaac
      721 aaggcggatc caattcgccg ctaagctgta agcttacgct atcagtttat cttttaaata
      781 taattaagat attcttactc tctgtggttg ctttaatatt tgaggattat tctgtaaatt
      841 agataaatta actacttgtg atttttttag tatattaaga ctcgcattta catctgcatt
      901 tataatgatt ccaacactgg atttgtactg tccacgcgtt attctttccc ctttaaagtc
      961 atatttttta atattgtcca cgttgatatc aggtagaaaa tcatcagcaa aaaaatctga
     1021 tttactagta tagctttctt cttgcctaat aaaattgata ttttttattt tacacagata
     1081 ttctaatttt ccttttatct ctccaaatgg gattcttata aaatttctat atatttttct
     1141 ctccatatta tcactttttt ctaacttagc attatatcct acaattaaat ttccaatatt
     1201 attttttaca caataatcaa ttatataaaa acaggtttta tttacatagt ctttaacttg
     1261 attatttctc ttattccaaa ctttaaattg ttttcttgtt attgcagtta tattcttttt
     1321 taattttaag gcttctattt tatcattctg tttgtttgcc cactgattaa cagattttag
     1381 cctttttcca tctatgataa aactatcacc taaattggta acacatgtac ataaattttc
     1441 taaacccaag tctatagcta gtgcattttt ttgatttgaa acttcctctg attttggtat
     1501 ttcataacaa tactgaattt caaagaacct agctttatgt ttaggtatta ttcttatttc
     1561 tttaattttt ttctctagta tattttgtgg aacttttata cttactttcc catatagttt
     1621 tttaaatgct ggagacatag gtacatttaa aatcccatct tctttgattc ttatttgacc
     1681 tattattatg ctaaaaaacc cttctttatc taaatattta ggtgatttta tccctctaaa
     1741 gtcatatttt ccttctttgg ctaatttaat taacccaaaa aatgacctaa acgaactgtc
     1801 tacttctttt aatatttgtt gcgctatatt actattgaga agcttatagt tctcattttc
     1861 tttgcataca tgataattag cttcatagtt aagatgttct ccttgattga aataatgctg
     1921 tcttacatta tatgtaccaa cattatataa gttcttagct aagaagcaca tctctcgtag
     1981 agcttgatat tcttttttag ttaagttttt taattgttgt ctctgagttc catagtgtat
     2041 attttttatt ctgtttgaca tgaactcacc tcctttagaa tatactctac tagacattat
     2101 atacggtatt tttacaaaac accatatata atgtccattt aattacttta ttttacaaaa
     2161 taatttaaat ttacttgctt ttatacacat tattatttat tataattgtt tattattatt
     2221 tttcataccc atataaactt tttcaaaagt cataggaagc tctcttaaac gaactcctgt
     2281 agcattaaat attgcatttg ctatagctgg tgctggtgta tgtataacta tttctcctaa
     2341 tgatttagca ccataaggac ctcctgggtc gaaattctca gcaaaatcta ccaatatatt
     2401 tccaacttct ttttttgtag gaactttata ctgtaggaaa ctatctgtta ataatctccc
     2461 atctttatca aatacagggt cttcatacat tgcaaaccct atacccatca tcacaccacc
     2521 ttctacttgt attctagcta aagttggatt tataactgtt ccacaatcag gtacacatgc
     2581 aaaatttatg actttatatt cgcctgtatt tttatctaat tctatctctg caaatcctgc
     2641 tataaatggt tttatttttt tcaacatgcc aaaagattct gttgcttcca aaactactgg
     2701 tacatcatca ctagcaaatc ctattcctcc aacagattct ctacccaatt cctctaatag
     2761 aacaaacttg ctattatcat ttttaacaaa aaccctgtct tttcccaact ctaaatcttc
     2821 ttttttaaat cctagctttg actctgcaac tgaaagtaat atatctttta atttatttgc
     2881 tgtctttatt gttgcatttc ctgtaaccgt tgttgtacaa gaagcaaatg ctcctgtatc
     2941 atagggacat aagtctgaat cacctgtata aatagaaatt ctatctacag tagtatttaa
     3001 agcttccgca gcaatttgag cttgaattgt atcagcccct tgacctaagt cagcaagacc
     3061 agataatagt ttatatgtgc catcttcatc cattcttata gtgactgttg ccatatctac
     3121 acgtggtata ccagaaccat gatttgctac tgccatacct actgctctta ctttgttgtt
     3181 tcctatatct ttacatggat atttatcatc ccaattaatt aatttcttgc ccttttctat
     3241 acattgtctc aactcacaac ttaatatttc gtcttcagct gcttttccat tggtatacct
     3301 atctattata tttttaattc taaattcaag tgggtccatt ccaatcttat gtgccaattc
     3361 atcaatagca ctatctattg caaatattcc ctgtgtagca ccataccctc taagtgctcc
     3421 tgctggtaac ctattagtat atactgttct agcattaaat ctaacagcat caatatcatt
     3481 atatattggt aaggtattgt gtccagattc ggaagaaaca gagacaccat tcccaccata
     3541 agcacctgta ttgtttaatg actttagctc tattgctttt aaatttcctt ctttatctgc
     3601 accaacttta acatcaaaaa acatttcatg tctactatta gaacctacaa aagtttcact
     3661 tcttgtaaat acaaattttg ctggtctacc agttttcata gtaacaaatg cagtaaatat
     3721 atctgttgct gctatattct ttcctccaaa tccaccacct attctaggtt taattactct
     3781 tatttttgaa gatggtatac ccagtacttt tctaagtatt ctctttacat tgtgtggtga
     3841 ttgtaatgat gaaactacaa caattctatc atttatatct ttatatgaat atgacctatg
     3901 agtttccatc atgcaatgcg attgactttg ggttttgtat gaagattcaa ccacaaaatc
     3961 actttcttta agcttagctt caacatctcc aaattcaaaa aattcttttg atactatatt
     4021 attttttgca tccaatccaa aagggtatgg ctctactatg tctttttctg gatgtataac
     4081 aacttcattt ccttctgctt ctcttgcatc aaacacaggc tttaaaacct cataatctac
     4141 ctttatcatt tttaaggctt taagtgctgt tttctcatct tcagcagcca ctaaagctac
     4201 ttcatctcca ataaatctaa ctgtatcttc aagtaaaact ctatcataag gtgatgcttc
     4261 tggttctgtt tgacctggca cacaatatct gacctgtggt acatctttat acgtataaat
     4321 acccacaacc cctggaattt tttcggcttt tgatgtatct atattcttta tcttagcatg
     4381 agcatgtgga cttctaagta gttttaatgt caaaacatct ttatgcataa tgaggtcttc
     4441 agtatataga ggttttcctg tgacaattgc tgtactatct atctttctta tccccttatt
     4501 aatcattata cattccctcc tcaatagcat tatacatcct tttaactaat gcacttgcca
     4561 tatcctttct gtactcttta ctagctctca tattacttcc ataagtaagt tccttactag
     4621 caacaataga tgccttatct atatcttttt ctttatttaa tatattactc gcttcaagtg
     4681 ctaatctagc tttttgaggt cttgccccaa ttgctatttt gtaagtatca ttttctttta
     4741 gcattgctga atttaataca gaaaaatctc ctgtgcattt tcttattgag tcaaaaacag
     4801 ctattgcatc tttttttggt agtattactt cgaccaatat atccctactt aattcactat
     4861 ccaaaaactc acttaactct agtattcctt tattgtataa tctcaccttc gctccaacaa
     4921 ccaaaagcgc tggtattaag tcagaaaagc catactttga aaatacactt gcaccaattc
     4981 tagccccttg tctaaattga acaccaacta tattagaaac agcgcttgaa agtattccac
     5041 tacagtaatt ttttatagtt ttatcaattt ctaaacttct aagtgaagta tctgcaccta
     5101 tcaaaatatt tttttcatcc tcttttatat aatttagatt tatatctttt aaatctatcg
     5161 ctgttcctat atttttatta cttaatttta taaatccaca tccacctaaa ataacattat
     5221 tttttttaga aattaaaatt ttatatgctt cttctaaact ctgtggaact gaatattcct
     5281 ttatagtaac catcttatcc ccccatcatt aacttattaa aacacaaaag tttttaataa
     5341 atcttttatt tatatttata attgtagtat atttaattca catatattaa acctttacat
     5401 tataaacttt tatttttatc ctcaacctta tcacttttat ttccaggaaa ttttaccata
     5461 tataaagctt gaattattat ggctaccatt gctcctgaaa ctacacttga atctgcaagt
     5521 aatgtctcta taaattttgg aaatttttca agaacttgag gagctaccat gaatccaata
     5581 ccagaagcca tagaaagacc taatatcatg ctattttctt gattaaatcc atccatacta
     5641 acaagtctta aaccagatgt tgtaagagtt gaaaatataa cgagtgttgc tcctccaacc
     5701 acacagggag gaattgttct tattaaatta gctaataaag gcgatattcc tgccaaaaat
     5761 aatccaattc ctccaatagc tagtacaaat ttacttacaa cctttgtatt ggaaacgatt
     5821 gcagaatttt gtccaaacat ccccattgga gttgcagaaa ataatgcacc tattgtagag
     5881 agtactccat ttcctaaaac agcagaagaa agttcttcat ctgttacttg tctattaagc
     5941 cctcctaccg cagaaagtgt acaagcaccc attatatcag ctatctcaac taaatatatt
     6001 attgaaaaca ttacaacaac ttcaagtctt atatctagcc caaaagcaag tggttttgga
     6061 agtgcaacca aagtaaactc ctgaattgaa gaaaaattta ctatacccaa aattaatgat
     6121 aaaatgtatc caaaaattat gctaactaat attgatgcat ctttaaataa tccttttcca
     6181 tacttattta atcctaatat cataagagat acagatattc caactataaa attaattgga
     6241 ttcccaaaag tctcattgcc cataccccca gctaagtttt ttatagctat tggaaaaagt
     6301 ccaagaccca tacatgcaac tattgttcct gatacagctg gagtaaatat aaatcgtatt
     6361 tttttaagac caaaaccaat tataattatt actataccag ctattatttg agagccaaat
     6421 aatactggta gtccatactt acttgcaaca gataccccag ctcctataaa catagctgta
     6481 gctcccatta taactggtat tcctcctcct aatttaaaac ctttaaacaa aggtattgga
     6541 tataattgta ataaagttga taatcctgca aaaactaatg cggcttgaat caataatgtt
     6601 gacatcttat gattaagtcc agctgcattt gcaatcaata tcgctggtaa acaactacct
     6661 attaccattg ccattaagtg ttgtaaccct aaaggtattg cttcctttag tggtggtatt
     6721 ccgtctaatt caaattttga tgtacttttt gctttcataa taaaaactcc cgttacataa
     6781 aacttattga attatataaa tacttaaaaa tctaatatat taaattaatg atgttcataa
     6841 atatcaacta tactccaaca tatatttaag tttttagtct taaaaaacag atgcaataaa
     6901 tttaattatt aacaaataaa cgtattcttt aattttgtat acattatata ccatgcttta
     6961 caaatataag agtattatag ctatgaattt ttaatttttt atagtaaatt taattcaatt
     7021 taaatctttc aatcttaatc attataagtt ataagttttc ataagtattt acatgtttca
     7081 agttttaaac atttacctat aaacgctact ttatagatgt cacttcaaat ccagtgacct
     7141 catactttca tatgagcgta gactatttct tcatcttcag cattacctgc taagagcaac
     7201 ccgtttccac tatcaatcgc ttatagtgta ctctctctcg agatagtcgt ttgaccttcc
     7261 tatttctagg cttggcgacc aaatgtccat ttttaagtac ttaggctctc accatatacc
     7321 atcctcacta ttgtttctgg ttttcaccac attcataaaa gtttctttct atcttttatt
     7381 gtagttgcaa ggctttagga tttactggtt ttaaagttgt gtcctacata gatttctcta
     7441 tgtacggggc caaaagtaca atttatttaa catactttgc tttaccccct gtaaataata
     7501 ttatttactc tttcactgtt tttgttatta aattaattaa atatcaatta atctaagcat
     7561 aaaataatta tttaatttaa actcaaaata tttatgaata ttttataata taattctcat
     7621 aagacagaaa aacttaataa gctatgtatc tcagttgtac caatgtactc tcctttacta
     7681 tatttgtatc tgcaacataa aatatacaag tttctatcta tttatagata tatatatcta
     7741 taagcaaaat agtaatatta tttttatagt aaaaatttta ttcatattac tatttataat
     7801 ttttatagag caattttagt gccaatattt gcatacattt gtatagtata aaatttttat
     7861 gttctcattg ataaaatttt acttatttca agcgttctat tagattttat catctaaatt
     7921 ttaggtttta tttttataaa ttaattgtat ttacataaaa aaaaagacct aaaaacaaat
     7981 ttttaacggt cttttctcat ttttttattt tcatttctaa aatttataat aaatagtaag
     8041 aacactataa attcttttat ataaaattct tagtttgtgg atgataaatt agtgaattaa
     8101 aatactactt tactgatttt agtttgacaa tatcactcca atttttacta gtggctaact
     8161 ctactaaatt taagtctctt cttatttcag ctatatcctc ttttatagaa ttagtgtcac
     8221 cttttatata tgctatgtta tgttctatat tatcatgagt agctttattt atttcagaat
     8281 tatgtaataa acttcctaaa atattattct gttctatctg tatctctttc attgatttat
     8341 cttcacattc tagactatca atcttaattt caattccata taatttttca tttactatgg
     8401 atacctcgtc cttaattcca ttcatatctt cattaatgtt atttatttta ttttgcataa
     8461 agtttacttc tgatttaact tcggaaacat cttctttcat tacagttatt tcttgtctta
     8521 cttctgacat gtcttttttc attacattta tctcttgttt tacctctgat gtatcttctt
     8581 tcattacagt catttcttgt cttacttcag acatatcttc tttcattata tttatctctt
     8641 gtcttacttc ggacatatct tcttttaata catttatctc ctgttttact tccgacatat
     8701 cttcttttaa tacatttatc tcctgtttta cttccgacat atcttctttc attacagtca
     8761 tttcttgtct tacttcggat atatcctctt tcattatatt tatctcttgt cttacctctg
     8821 acatatcttc tttcattaca atcatttctt gttttacttc cgacatatct tcttttaaca
     8881 catttatttc ttgttttact tccgacatat cattttttat gctaactaca tcttcattta
     8941 tagtatataa taactctaaa atcttctctt gcacttgcat caccatccct attaattatt
     9001 ataacatttt acacaaatgc tatacaatgt taacatatat atcagaatta ttaaaatttt
     9061 aattaaacaa aattgattca ctttattact tcaaaactaa ttaatatcta aaataactac
     9121 aaataaacaa aaataaggtc aacaacaaaa aaggcttatc tctttgagat agcctttctt
     9181 atttttattt aaaactttgt tttttataaa ataatctata cattcagctc tgaacatgaa
     9241 atttttcttc caagtgcttt tggtttacaa actgatatac aaagtccaca atatctacac
     9301 tcttcttcat tcaattccat cttatcattc aattttctcg cttgatatgc acaaactctc
     9361 tcgcacatct tacatttagt acatttttct tcatcataag taaactcaaa gctaagtctt
     9421 tcattaacat ctcccatatg attatgtact ataccacaag cattttctat agtattatat
     9481 cctaatctat taagattaga ttttaaatca tcatgtattt tagatattac ttgtgcgcct
     9541 tttaaaatta ctactgaaca tataccaaca aagtcagcac ctgccataat catttctaag
     9601 gcatcatctc cacttacaca tccacctaag ccaattattg gtatattaac ttgttttttt
     9661 atttcatata ttctctgtaa agttattggc ttgatagttt ctccacttaa atatcctatt
     9721 ccatttccac ctaataaagg ttgccctgtt tctatgtcta ttctaaatgc tggtcctaca
     9781 gagtcacaag cagttattgc atctgctcct gcttcttcta attttttagc aaaatcgcct
     9841 atctcatcta tcataggagg aagtttaact attacaggta tatttactct ttcctttgca
     9901 tctttaagca ttggtatcaa atctctatag tcataagata ctaattcaat aaagtcagct
     9961 cctgcatttg caactttctc tactaattcg ctactttctt caattgtatg acctattgaa
    10021 gctatacaga cagtcccatc tcttttcatt tgtggtattt caaaatctat ccattgctct
    10081 ggctcaaaat ctgtccattt ttcattattt aaaagagcat tagctgtatt tctaaccata
    10141 tgtggtgctg gatttatagc tctttctttt cttatagtct tagtcacaac tgcccctgct
    10201 cctgcatcac ttaatatctt gcatccagct gcactatatg ttaatggtcc tgaacctatt
    10261 ataagtggtg attttaattc tttacctaaa aaattataca ttatctgctt ccccttttca
    10321 tatatattta cattcgttaa aatttccaaa attcacaagc aacttctttc atttctttaa
    10381 caatagcttt tttatctaaa tcaactaact gtttttcttt taaaatatgt ctaccatcta
    10441 tgtatacatt tgatataaat tcttttttac cctgaactac tatctggtca aatatattat
    10501 caagagtcac aggagtttta aattcatctt ccataactat tatatcagcc ttattaccaa
    10561 ctgctatttt accagaattt tgaagtccta atacataagc accatgctct gttgccattc
    10621 taaatactaa atttgctggc attactgatg catcttcttc aactgattta tgcattaaaa
    10681 atgcacctct cataacttca aaaaaatcat ttatatatcc gtcagtaccc agtgccactt
    10741 ttatgccttt tttaatcatt tttggtactg gagaaaaacc tccacctact tcacagttgc
    10801 taagaggcat atgaaccact tttacacctt tttcttttaa tatatctatt tcttcatcat
    10861 ttacttttac acactgagat gctaatacag tttcatccaa tatatctaaa tcattatagt
    10921 agtcaactgc ttttttgcca aaatgttttt cagcatagtt tggctcatat atactctcac
    10981 ataaatgaaa ttgcattggt gcatttaatt tttttgcatc ttctttagct ttcttaataa
    11041 atctatcaga acatgtgaag cttgtatgtg tacacattat tccatttatt aatttactat
    11101 tttctctgct ccactttatt aaattagaat tttcatctaa acatctaagt ccattttcaa
    11161 agcttattct ttcacaactt tctaaggata aaatcgcttt catgcctatt tcttctagta
    11221 tttttccttg ctcaattaaa gttccttctt ctgtatttgg agcttctagg gtatcacaaa
    11281 aagctaccac accagattct ataagttcta ttgctgatgc tttagttgtt gccttcactt
    11341 ctttcaatcc aattctattt tctataaatg gccaccaata gtcatttaag aaaccttcaa
    11401 agtcggtaaa atgtacattt gccggtattc ccctagaaag aactccatat tgatgcatat
    11461 gaccattgac aaatcctggc attattatag catctgattt atctattatt tcttcaatat
    11521 ttttatattt tatttcaact tcttcatttg gcaatatatc ttttataatg tcattttcta
    11581 ctacaacagc agaatttgta tatatttcat cagcagaaga tattaagtat ttacttttaa
    11641 tagcaatcat ttatttacct ccctgattta attttttcat ggccatataa actttctcag
    11701 aagttatagg aagttctctt atacgaactc ctgtggcatt gtatattgca tttgctattg
    11761 ctggtgcagg tgtatgaata actatctctc ctaaagattt agctccatat ggacctgttg
    11821 gctcataatt atctacaaaa tcaacaatta tgtttcctat atcttttttt gttggaactt
    11881 tgtattgtaa tagattagaa gtttgaagct ttccatcaga accatgtcta gggtcttcat
    11941 acattgcaag ccctatacct tgagttacac caccttcaac ttgtattcta gcaagtgcag
    12001 gattcataac tgtaccacaa tctgtagaac aagcataatt tattacttta aactcccctg
    12061 ttgttttatc taactctatt tcagcaaagc ctgctaagaa tggtttagca ctctcttgta
    12121 taccataaga ttcagatgaa tataaaactt cttgatttcc accaccaaca gattcttttc
    12181 ctaattcact taacaaaaca aacttctcta catcttcact ataacaaact ctgtcttcat
    12241 atagtattaa atcatctatt ggtaaatcga gtttcttctg tgctactttt aatatctttt
    12301 gttttaaact ttcagcagat tttattgtag catttccagt tacataagta gtacaagaag
    12361 cgtatgcacc agtatcatat ggacacatat ctgtatctcc tgtataaacg gaaattctat
    12421 caatagatgt attcaatgct tttgcagcta tttgtgcaag tattgtgtca gaaccagttc
    12481 ctaagtctga agacccagaa aacaacttat aagttccatc ttcatccatc ctcatattta
    12541 ctattgccat gtctatgttg gctataccag aaccatgagt tcccacagac attccaacag
    12601 ccctcacctt attgtttcca atatccctaa cagggtactt ttcatcccat ccaataagtt
    12661 ttttacctct aattatacat tcatcaagtg cacaacttct tattggaaaa ttcattattc
    12721 cgccttcagt ttgttttttt ataatattct ttaactttat ttctgttggg tccatattaa
    12781 gtttatgcgc taattcatca attgcacaat caagtgcaaa tgtaccttgt gttgctccat
    12841 atcctcttaa tgctcctcct ggaactaaat tagtatatac agttctccca tcaaatttta
    12901 ttgcaggtac attattatat gttggaagta cattatgacc tgattcagag caaactgaag
    12961 gtccattatc accataagcg cctgtattgt tcaatgcttt catatctata gcttttatgt
    13021 ttccttcttt atctgcccca atttttatat caaaaaacat ctgatgtcta gtattagtca
    13081 ttgcaaaagt ttcttctcta gtataaatta gttttgctgg tctttttgtc atccaagtta
    13141 caaatgatgc atatatctct gttacagcta tgttttttcc accaaaacct ccacctattc
    13201 ttggttttat tactctcact tttgaaagag gtattcccag tgctttagaa acctgtcttc
    13261 tcatatgata agctgattgg tttgcagaag ttactactaa tctgccattc gtatctatat
    13321 acgtataagc tctatgagtt tccatcatac aatgggcttg tgattgagtc atataagaat
    13381 gttctactat tacatcactt tctttaaact ctttttctac atccccttta cccatttttt
    13441 ctctcgatac aatatttttt gtagcatcca atccaaaatc aaatggacaa aacaaatcat
    13501 cttcttcatg gattaaaatt ttatttcctt ccgattctct tgcatccaat ataggagtca
    13561 ttacttcata ttcaactttt ataagtttca tagctttaat agcagccctt tcatcttcag
    13621 cggctattat agcaacttca tctcctacat atctaactac gtcttcaagt attaattggt
    13681 catgaggtga tgcttctgga tatgactctc caaccattga atatctataa tttggaacat
    13741 ctttgtaagt gaatatgttt actacacctt ttacctttaa tgcatttttt atatctatgt
    13801 tttttatctt cgcaaaagca tgtggacttc taagaagctt aattgttaaa acatctttgt
    13861 gaaaaattaa atcttctgta tatattggtt ttccagtaac aatggcttca ctatctattt
    13921 ttcttacctc tttatttacc atcacactca cctccaatac tattatacat tctcactact
    13981 aaggcttttg ccatatcttt tctgtattct ttacttcctc ttatattact tccaaatgaa
    14041 agttcttcac ttgatacttc accagctttt tctatatcat tttctaaact taatatttca
    14101 cttgctttat aggcaatttt tgctcttctt ggtctagcgc ctattgcaat tttataaata
    14161 cttccttctt ttaacattgc tccatttaat actgcaaaat cacctgtaca ttttcttata
    14221 gaatcaaata cacctatagc atctttttta ggtaatataa cttctattaa tatatctttt
    14281 tcaagctcac tttctaaaaa atcagctaag ttcataaccc cttttttata taacttaacc
    14341 tttgcatcta ccactagtaa tgaaggtatt aaatctgaaa atccatactt agcaaatacg
    14401 ctagctccta ctctagctcc acttctaaat tgaactccta ctatattaga aacagcgttt
    14461 gaaattaccc cattacagta atttttaata accttattta attctaaagt tcttaaactt
    14521 gtgtctgctc caattaatat gctatcatca gtttcattta tataatctaa agctaagtct
    14581 tttaaatcta ttgctgagcc aatattttta ctacctagtt ttaaaaatcc acatcctcca
    14641 agtattatgt tgttttttct tgatattagc agttcataag cttcatctaa actttttgga
    14701 actacatatt cctttatagt tatcatactc tctccccata tcaacttaat tttcacttaa
    14761 aagtctaagt gtttaaatat ttatgtattg ctcttaattg acctttatat cctgtacatc
    14821 tacaaaggtt accatttaca taatctataa cttcttcttc tgttggattt tgaagctctc
    14881 ttttcattgc caaaaccatc attataaatc caggagcaca aaatccacac tggtcagccc
    14941 cttcgtctgc aagaaaatct ccaaacttct ttgcttcatc caagacaccc tcaagtgttg
    15001 taatatgctg accgtctact ctagcagtaa gataattaca tgaaagcacg gccttgtcat
    15061 ttaccatcac tgtacataac ccacatgagc ctgtatcaca ccctttttta acacttacat
    15121 atccattttc tcttaatgta tctgctaaaa aatcatctgg tcttatactt aattcttttt
    15181 ctttattatt tatggtacat ttgataatca aataaatcac ctcaaaactc atatttttaa
    15241 gctaaagttt tactatactt ttttatgaat aaattacatt tattaataaa ggctattcca
    15301 tttatgacct tccattctat tttttatagt tcctcttaca caaagtcttt cagctgtatc
    15361 ttgagcatct tttaatgctt tctcttcatt agctgtcaat atttttgaac cttccattat
    15421 tatatttcca tctactataa cactctctat atttttcata ctagaagaat atactaatgt
    15481 agataccgga ttatgcatag gtatcgcttt tggtgaaagc attggattaa atattagtaa
    15541 gtctgctttt ttacctatct ccaatgaacc tatctcatct tccattccaa tagctcttgc
    15601 tccatctata gttgccaact caagaacttt ttctgctgac attgctaatg ggtcacactt
    15661 attaacttta tgttgaagtg ctgttaattt cataagttca agcatatctt gagagttatt
    15721 actagcggct ccatctactc ctaaactaac tgttattcct tttttaagca tttctggcac
    15781 tggtgcaaca cctgaagata agtacatatt acttgctgta ttatgagaca ctttcatatc
    15841 atatttttta gtaagttcca tatctttttc agttagatac acacaatgta ccataagcac
    15901 atttggtcca agtattccta atttttctaa aacatctatg tcatattgcc catgcaattc
    15961 ttttgctgct tctctatcaa aaggagtctc tgatatatgt actgtaaata aagcatcatc
    16021 atattctttt actactctcc atagcatttc aagcatttct tgagaatttg accatattgc
    16081 tgcaggagct actcctattt tgattcttcc attttctgta ttatggtgtt tttcaaacaa
    16141 tcttcttaca tctttttcaa ccgtttctac atcttgcatt attccaggat gaactccaaa
    16201 ttgagctcct gtattcatac atcctcttcc aagtattcct cttattccta attctttata
    16261 agcatctatt attccatcac aaagacctgg cttactatga ggatacatgt agtcaaccat
    16321 tgttgttata ccacttctaa gtccttcaat acatccaagc attgcagcat cataagtatc
    16381 ttttggttct aaatagttag ctgctggaaa tgtcatagtt tctaaccagt ctttaagtac
    16441 catatcatct cccaatcctt ttaataaagt ttggaataaa tgattatgtg tatttataaa
    16501 acctgggaat aaaactttac ctttagcatc tataattttt ttaacatcag tatatttact
    16561 ttctatctct ttagaatttc caatatcagc aatcttgtta tcttttacta ctaatgcccc
    16621 atcaaaaata acttctctct ctttattcac agttactatt atggcattct taataagtat
    16681 atccatcatt cttatttccc cccgcattat ttagtaattt ttcttttaat atattgacct
    16741 gttggatgtt ctttaacatt acaactttgt actacatgat ttcctctcaa aaatacatct
    16801 tcaactttac atttaacctt aaatccttca tatggagtat aatctacatt ttgtttttga
    16861 gttttataac taattgtttc ttctttattg atatttaaaa tgactatatc tgcatcactt
    16921 cctacagcta tctcaccttt tttaggatac attccaaata tttttgcagc attcgtagaa
    16981 gtaacttcca caaacttatt tacacttatt ctattttcta agaccccata tgtatataaa
    17041 agtgctaacc tatgttcaac accaggtgct ccatttggta tcttactaaa atcatcaatt
    17101 cccaagtctt tttgcccctt aaaattaaat gaacagtggt ctgtgccaac tgtttgaata
    17161 tctccactag acaatccttc ccaaaggtaa tttatgtctt ctttttttct taaaggagga
    17221 gacattacat acttagcacc ctcaaattta tccttattat ataaattgtc ttctaataat
    17281 agatactgtg ggcatgtttc tactatcata tctatgtttt tttctctagc catttttaca
    17341 gtttcaagtg actccctaca acttaagtgg actacatagg attttgaatt agataattta
    17401 gttatatcag caagtcttga aacagactct ttctcaacta tgttaggtct tgtaagtgga
    17461 tgatattttg tctctaaatt accattttgt atattttctt ctatcaatac atctagtaaa
    17521 tccccatttt cacaatgaaa tccaactata caacctaaat cccttgcttt ctttaaaacc
    17581 ctgtatattg ttccatcatc tactttcatg ccatcatatg ccatatacat cttaaaagat
    17641 actatcccat ctgaaataag tttttccata tgattaaatg tatctttatt taaacatgta
    17701 attgtcatat gaaaaccata atcacaataa caatttccac ttgctttttt atgatatgct
    17761 tctacacctt gcagtaggtt ttccccctca ttggcttctg caaaatctag tattgtagta
    17821 gttcctccag ctatagctgc tcttgttcct gtttcaaaat tatctgcagt tgtaatagaa
    17881 cctgcattca tatcaaaatg agtatgtgtg tctattccac caggaattac aattttacct
    17941 gtagcatcaa taaccttatc accatttatt tctaagttat ttcctatttc aactatcttt
    18001 tcatcttcta tccttaaatc acttatataa gtcttatcag aggtaattat agttccacct
    18061 cttagtattg ttcccatata tacctcctaa cttttaagct ttaaagtatt ttctaagtat
    18121 tgtaaaactt tatttaaaat tgtattttct aaaggtgcta tattcagcac ctctagacta
    18181 tatttaaata atttattgtg aactaaatat tattttccgt atacagattt taatattcca
    18241 tagtaacctt ctgttcctat aaataactgt tcttgctcta tatactcatc tattgtgtga
    18301 gcaagatttt ccttagaagg accaaatcct atagttttta ttccagcttc acctgcatag
    18361 tgacttccat tcgtacagaa tgagtattga gttatttctg aatctattcc agcttctttt
    18421 aatcccttat atgctgcttg aacaaattca tcttcttcgt catataacca acctgggaag
    18481 aatctttcac tttctatagt atttcctgta tagcaatcag ctttttcaac cgcataagaa
    18541 acttttgcat ttaattctgg gtcttctttc atcatttcat ctaataaagc ttgtattgga
    18601 gctaatacgc cttctcttgt ttctccaact aataatcttc tatcaaaagt agctttgcaa
    18661 taatctggca ctactgatgc tcctggatat ggagaagatt ttatatctgt taaaactaat
    18721 attccatcac ctaaaactgg atgagttgga ggtactaatt gttgtatctt ttggattaca
    18781 ttag
//
LOCUS       DAEORM030000068        18639 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.069, whole genome shotgun sequence.
ACCESSION   DAEORM030000068 DAEORM030000000
VERSION     DAEORM030000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18639)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18639)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 18639)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18639
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.069"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            210..1538
                     /locus_tag="KRH23_003193"
     CDS             210..1538
                     /locus_tag="KRH23_003193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015171 - amino acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HHS5226467.1"
                     /translation="MGSNELKKTLGVSAALSTVVGSVIGAGVFFKPQAVYTLTGGAPG
                     LGILAWLIAGIITITAGLTAAEVSVAIPKTGGMMVYIKEIYGEKLGFLTGWMQIVLFY
                     PGMMAALGVIFGEQASALIGSPSLLLPIAIGIIIIVAGLNMLGSKTGGVIQTVSTICK
                     LIPLILIMVVGFIKGGGNNPILTPMVGEGLSLGSVLGQVLIAILFAFDGWMNVGTLAG
                     EMKNPGKDLPKAIIGGLSVVMAVYFIINLAYLWVLPANELANYASPASAVAEVIFGSM
                     GGKIISVGILISVFGALNGFLLTGSRVAYTLATDKTLPKYGIFSKLNSAQVPANAIAL
                     VSVIASIYALSGQFNLLTDLAVFATWIFYVLTFIGVMKLRKTHPNIPREYKVPLYPIV
                     PIIAIASGIFVVVNQLCFAGMKTTMISIGGLVITAIGLPVYAYMTRGVKR"
     gene            2291..3124
                     /locus_tag="KRH23_003194"
     CDS             2291..3124
                     /locus_tag="KRH23_003194"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HHS5226468.1"
                     /translation="MRNKKKKINRKKLYLLLSAIVVCLAFIVVGVRVSSLNMKENEIS
                     RNAKLSSSTITDIVSNTSIEVSKGPSKSSGKIAYITIDDGPSKFTDQMIKTLNKYNVK
                     ATFFMIDGNMKEYPQQVKNIIKNGNTAGFHSVSHDIHKLYVTSTSAKEEFDTNDQTFY
                     KITGKHSKVIRIPYGSKPYTPQASYQALVDAGYKIWDWDLDTEDWRSNSSQIVQNVKN
                     HIKNRKGEDKDQLVVLMHEKKQSAEALDSVLKFLSDEGYEFAPVDQNQIPKNYWLRNL
                     E"
     gene            3193..4149
                     /locus_tag="KRH23_003195"
     CDS             3193..4149
                     /locus_tag="KRH23_003195"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HHS5226469.1"
                     /translation="MNKKLYIGMVGILSLMMVGCNKSLAKVNDVEITKEQYKKTKAVL
                     SATNNYINGQSLDELEKTLDKKGRNKLENVIISFMVDNELLYQEAKDKGLTPSKSEVD
                     SKYQELEDKMNLNTSYKEKMDKAGVDKDYLKQEISRDLAIDKNKKAFEDRINISDNDM
                     EAYYTSHKKDFNVEEVSASQILISTLDKNKKEVSKDKKEALKKKADNILTKIKNGESF
                     ESLAKKYSDDKATGKNGGQLGYFTKDDKNAEFTKEVFKLKKNEVSNVFETSYGYHIVK
                     VTDKRERQKSFNECQSLIRESILNEKYIEHIKKLNEDAKIDR"
     gene            4201..4683
                     /locus_tag="KRH23_003196"
     CDS             4201..4683
                     /locus_tag="KRH23_003196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HHS5226470.1"
                     /translation="MFKSLKRTKVEKYIIDNKDSFYRIAYSYTKNEEDALDVVQEAMY
                     KALYSVENIKEVNYIKTWFYKILVRTSIDFIRKNRKYNNMTDIDLIDETGEYDKYTDL
                     DLRRALEELPIEYKSIIILRFFEDLKIEEVAIILDENVNTVKTRLYTALKKLKLKIEE
                     "
     gene            4695..5564
                     /locus_tag="KRH23_003197"
     CDS             4695..5564
                     /locus_tag="KRH23_003197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HHS5226471.1"
                     /translation="MTSKERLNKLKDEYHKIPIPKKLDTIINHEKIENIYREKNKKVN
                     RLRFKVAIAFACIFTVLVNISPVFADNFSKIPVIGAIVEVITIKNYSLKSENYEAEID
                     IPKIRGLKDKNLEQRLNSSFMEDGKRLYHQFQERMEKIQSSKNKGYKSLSLSYSVKNN
                     SKKFLSIEMTKNEIEASSYVSKVHYTIDKKRQIVLTLPMLFKDDKYIKVISDNIKEQM
                     REQMKKDSTKSYFIDQKKDLPVEDFKTINKYQDFYFNKNEDLVICFDEYEVAPGYMGA
                     VEFVIPYKVIKDL"
     gene            5607..6362
                     /locus_tag="KRH23_003198"
     CDS             5607..6362
                     /locus_tag="KRH23_003198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HHS5226472.1"
                     /translation="MTTYKKLKKSIFKIAIFSICLLVSLVDTNPIFAGSSFNETSNSD
                     TIKVLNAKSINFKQDNYEVNVSIPKIKGLKDKTLENKLNNELLQDGKKIYSEFQNKMK
                     KENNKGHRYLNVIHNVKNNSKDFLSIEMTKEEIEASSSITKKHYTVDKNRGILLNLPI
                     FFKDSRYIKAISDNIKEQMRNQIKKDDTKSYFIDQDKDSPVKDFESINKYQDFYFNKN
                     GNLVISFDEYEVAPGYMGAVEFVIPNKVIKRLR"
     gene            6404..7225
                     /locus_tag="KRH23_003199"
     CDS             6404..7225
                     /locus_tag="KRH23_003199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="XdhC family protein"
                     /protein_id="HHS5226473.1"
                     /translation="MNIYEQAIRLIENNEDFAFATITSHSGSTPRETGAMMIVKNDST
                     IFGSVGGGSVEAECIKHAINVIKNRESMLYKFTLNKSDVAKLGMICGGTGEIQIDFID
                     SKLKSNIEKFNKRLKENTSKAYIFGAGHISRDVAVILSLLEFRTVVIDDREEFANHER
                     FPESEVVVLDSFENIPDFPTDENSYIIILTRGHLYDSSALEWALKREAGYIGMIGSRT
                     KIGLTYEKLMKKGFKKEELSKVHAPIGIKLNAQTPAEIAVCIAAELINCRANKEK"
     gene            7230..7991
                     /locus_tag="KRH23_003200"
     CDS             7230..7991
                     /locus_tag="KRH23_003200"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0008237 - metallopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M48 family metallopeptidase"
                     /protein_id="HHS5226474.1"
                     /translation="MNTGSKDIDTLKVNFRGIEIKAVLVYKNRKNISIKIDPFGKITV
                     MSPPKISKKIIKDIIIEKGDWILKKSEKCKGREEVYKQRMFITGEKFLYLGEEYHLVI
                     KELLRDSVKKSNCRITINEYQIVVQTNDTSTDFIKKSLKSWYKMESERIVLERIDFLK
                     LNCEIMKKLVPASVKVKEQNKRWGSCTAQKNIYINSKISMARLDVIDYVIIHEFSHLV
                     HMNHSKKFYDLVKSIMPDYKDKENWLKINGYKIII"
     misc_binding    8152..8409
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            8522..8761
                     /locus_tag="KRH23_003201"
     CDS             8522..8761
                     /locus_tag="KRH23_003201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HHS5226475.1"
                     /translation="MENTVYAKLNQGIDSFLRVAMTLRRREVDIQSISMTVDNMNNSG
                     IKLIVNEEKTSLDSVLNHMKKLHDIREITVERMRH"
     gene            9014..10060
                     /gene="ilvC"
                     /locus_tag="KRH23_003202"
     CDS             9014..10060
                     /gene="ilvC"
                     /locus_tag="KRH23_003202"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HHS5226476.1"
                     /translation="MSNKNKYHKNKKKYWEEMKMARMYYEKDVDLEVLKNKKVAVLGY
                     GSQGHAHAQNLRDNGVHVMIGLYDGSKSAQKAKEDGFEVKSVAEATKESDLTMMLMPD
                     EKQKKVYEESVKDNLKEGQTLAFAHGFNIHYNQVQPPEFVDVVMVAPKGPGHLVRNVF
                     TKGSGVPALFAVYQDYTKKATETVLAYAKGIGATRAGVLETTFKEETETDLFGEQSVL
                     CGGISELIKLGYKTLVDAGYQKEVAYFECLHEMKLIVDLIYEGGFERMRYSISDTAEY
                     GDYVSGKRVITDAAKQGMQNVLEDIQNGKFAKAWIKENEEGRENFLKTREEEYNTEIA
                     EVGRNLRSMMSFLK"
     gene            10113..11801
                     /gene="ilvB"
                     /locus_tag="KRH23_003203"
     CDS             10113..11801
                     /gene="ilvB"
                     /locus_tag="KRH23_003203"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0003984 - acetolactate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0009082 - branched-chain amino acid
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="biosynthetic-type acetolactate synthase large
                     subunit"
                     /protein_id="HHS5226477.1"
                     /translation="MNGAKVILECLKKEGIDTIFGYPGGAVIPLYDALYDYSDDFKHI
                     RTSHEQGLVHAADGYARSTNTVGVCFTTSGPGATNAITGIATAFMDSSPMVVISGQVP
                     TSLLGKDSFQEIDITGATLSMTKHNYLVRNTKELVPTIKEAFRVANSGRKGPVLVDVP
                     KDLFLAEMDFSGEDYDLCQIDDYMDYKSDFDLDDETNIKLLNEAIDIIKESKKPVIYA
                     GGGVKSSDSEEILEKFATKIDTPVLNTLMGLGNIDRKNELSLGMVGMHGSRESNLALS
                     NSDLVIAIGARFSDRVISKSSEFAKNAKIIHIDIDPSEISKNIESNVSLVGDVKLVLS
                     LLIERVESKNNSNWKEEIKRFRKSEGVQTYEFHPQNILKKINEKYETLKKPTVVVTDV
                     GQHQMWAAKYWNFKGNKSFITSAGLGTMGFGLGAAIGTKVGNVDKNVVLVTGDGSFRM
                     NCNELATVANYNVPMLILLLNNRTLGMVRQWQKLFSNQRYSQTDINENVDYVKLVNAY
                     NIDGYKVSSMEELGKALDIIDFNKPVFLQCDIDKDYDVYPIVAPNDALENLICN"
     gene            complement(12159..13289)
                     /locus_tag="KRH23_003204"
     CDS             complement(12159..13289)
                     /locus_tag="KRH23_003204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HHS5226478.1"
                     /translation="MKGGVRKRSNKWYYYFDLGIVEGKRKKVERVGGNTKKEAEKALR
                     EALNEYENSGIVFEESNISLSDYLDFWYKEYVLLNCKYNTQESYRINIEKHIKPKLGA
                     YKVKALTPAILQNFINKKYKEDYSQNTLQVLKAILHRSLKSAVHPYKHIRENPMQYVS
                     IPKTKSKTETNKVKTITLEEFNQILNIFPQDSFQRIVLLIGFHTGMRRGEIIALKWDN
                     IDLDNKTITVKHTLIKKPNGMFELGQPKTESSCRTIFTGDTLIKALKEHKLYQKKMKL
                     KYGEFYFDSDWVCTKENGQQVNTHTLDTIVRQIRVALNNDFHFHSLRHAHATLLLENG
                     ANIKDIQNRLGHSQLSTTMDTYSHVTDKMKNETVDIFEKITN"
     gene            complement(13529..14035)
                     /locus_tag="KRH23_003205"
     CDS             complement(13529..14035)
                     /locus_tag="KRH23_003205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HHS5226479.1"
                     /translation="MNKLDALLDLANNEEIEIYYTDKIADDIKGLYINRQGLKIISLL
                     NSLKQNNAKLIEILAEELGHHFTSVGNYVSSKNSYKNKILIDKTENKALKWACEFLIT
                     EEEIIHVINSHATSVYEIAEELQVSINFLLKRLEFLSKKKSMLDLGNNRFLVLTNLPN
                     FYIYEDIF"
     gene            complement(14298..15887)
                     /locus_tag="KRH23_003206"
     CDS             complement(14298..15887)
                     /locus_tag="KRH23_003206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIR2 family protein"
                     /protein_id="HHS5226480.1"
                     /translation="MKSIISDVINRFNATPFLFVGSGLTRRYYNLPNWEDLLKVFAEK
                     ISNDDFIYTSYKNKAKSENPKMGINPRIAELIENDFNKKWFSDSSIRSLDSKYLDIVK
                     SGVSPFKAEIAMYIKNNSKIVDKYQDEVEKLSNISKKSLSGFITTNYDCFLETIVDNY
                     TTYIGQENLVFSSIQGIAEIYKIHGCVSSPNSIVINEADYIDFDSKSAYLAAKLMTIF
                     VEFPIIFIGYSVTDVNIKKILNAIVNCLSNENAKKLEERFIFIEYEKNFNDIEISSHT
                     IAFDNKMITMTKIKLEDFNLLYEALSEKKSKLPVRILRMFKQEFYDFTITNKPTAKIR
                     VGSVDDTRIKDEDLVLAVGKASDFGLKGLKGLSFDEWYRDIVMNDLEFSSDELLEYAY
                     PSLIKQYNKLPLNKHLFNSTLEFPDYRTIALESDFENIISNSIKKNRNNTYIKNRSVY
                     GIWNDEHQSFEKATRLIAFLEEKEIDTEQLENLLKKIFEENPNILESAKTSEKTNLRR
                     LIRIYDYMKYSNMQKSLGYSE"
     gene            complement(15911..16474)
                     /locus_tag="KRH23_003207"
     CDS             complement(15911..16474)
                     /locus_tag="KRH23_003207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHS5226481.1"
                     /translation="MSILSDRLKFLRKEKGVMQKEIANYLNITTSAYGFYEQGKRTPT
                     PEMLSSLAEYFGTTVDYLIGRYDNKASNISSKTSCNNTLFQKRLKELRAEKNMTQEDV
                     ANKLNLTKSAYGYYEQGKTVPDAYMLSSLAEIFNVTTDYLLGRSIVKNDIDTVAAHRV
                     NPHKDLPEEAQEQLNDYIEFLINKYKK"
     gene            16627..16848
                     /locus_tag="KRH23_003208"
     CDS             16627..16848
                     /locus_tag="KRH23_003208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HHS5226482.1"
                     /translation="MNNLKELRTERNLKQKDVALKVGITTSYYGMIESGTRVPSLAIA
                     IKLSKCFGVSIEKIFLNTNTTRCCLKERS"
     gene            16851..17666
                     /locus_tag="KRH23_003209"
     CDS             16851..17666
                     /locus_tag="KRH23_003209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor KilAC domain-containing
                     protein"
                     /protein_id="HHS5226483.1"
                     /translation="MKDLKIVKVNNKLTTDSRDIALMVEKEHKILLRDIRNYINQMEE
                     ANKNMSTDLYPSDYFIENTYLDDYKREKPCYAITKIGCDFIANKMTGIKGTAFTGIYT
                     KKFEEMEQVLKNEQPKLPTTYKEALQHLIEQVEVNEKLQLEGKMKDQVIKELKPKADY
                     TDMILKNKGLVTITQIAKDYGMSGKEMNKILHERGIQYKQSGQWLLYKQHQGKGYTHS
                     ETIDITRSDGMTDVKMTTKWTQKGRLFLYDLLKVNNILPDIEKEYSYQTSMLC"
     gene            17715..17843
                     /locus_tag="KRH23_003210"
     CDS             17715..17843
                     /locus_tag="KRH23_003210"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226484.1"
                     /translation="MSNRKKYTLSITKELYNKCKEKANQRGMSVNDYILSVISKSI"
     gene            complement(17845..18024)
                     /locus_tag="KRH23_003211"
     CDS             complement(17845..18024)
                     /locus_tag="KRH23_003211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Arc family DNA-binding protein"
                     /protein_id="HHS5226485.1"
                     /translation="MSTSLPKYTLRINRVLLEKIKYIAESEGRSANKEIEQIIKKHIE
                     DYEQRKGEIKINIEE"
     gene            18160..18339
                     /locus_tag="KRH23_003212"
     CDS             18160..18339
                     /locus_tag="KRH23_003212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226486.1"
                     /translation="MNSNKKRITVRMPEKLNEEITKKSKYLGLTKNSFILDILWKEFE
                     LLEYRSYKKEVDKHE"
     gene            18332..>18639
                     /locus_tag="KRH23_003213"
     CDS             18332..>18639
                     /locus_tag="KRH23_003213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ORF6N domain-containing protein"
                     /protein_id="HHS5226487.1"
                     /translation="MNNLQVIERNNERVLTTQQLADVYETDSRNISNNFNNNKDKFIE
                     GKHYFLLQGDDLKNFKGIHTEYENLKFASKMYLWTERGANRHCKILDTDKAWEQFDNL
                     "
BASE COUNT         7316 a         2029 c         3051 g         6243 t
ORIGIN      
        1 acatttactt agaagtatta ttatatttgg atttttggtt tttataattt ttttatattt
       61 aaacataact aaaaataaaa gattactaaa gctaagtaga gtttatttta ttttaataaa
      121 taataaagct atttttctat atattggcat aatatatgct tatttaacta tgaaattaaa
      181 attaaatagg attaatgagg aggaaaaaaa tgggaagtaa tgaactgaaa aagactcttg
      241 gcgtatcagc agcattatca actgttgttg gttccgttat aggagcgggc gtatttttta
      301 aaccacaagc agtctataca ttaactggag gagctccagg tcttggtata ttggcatggt
      361 taatagctgg aatcataact ataacagctg gtcttacagc tgcagaggta tcagttgcga
      421 taccaaaaac tggtggaatg atggtatata taaaagaaat ttatggagaa aaattaggtt
      481 ttttaactgg atggatgcaa attgtattat tttatccagg gatgatggca gcattaggtg
      541 ttatatttgg agaacaagca tcagcgctaa ttggtagtcc atcactttta cttccaatag
      601 caattggaat tataataata gttgcagggc ttaatatgtt aggttcaaaa actggaggag
      661 tcatacaaac tgtttctaca atttgtaagt taataccact tattttaata atggttgttg
      721 gatttattaa aggtggtgga aataatccaa tacttacacc tatggttggt gaaggattaa
      781 gcctgggtag tgtactaggt caagttttaa ttgctatatt atttgctttt gatggatgga
      841 tgaatgttgg tactttagct ggagaaatga agaatcctgg aaaagacctt ccaaaagcta
      901 taataggtgg attgtcagtt gttatggctg tttattttat aataaattta gcgtatcttt
      961 gggtattacc agctaatgaa ttagcaaatt atgcttctcc tgcatcagca gttgctgaag
     1021 ttatatttgg ttcaatgggt ggaaaaataa tatctgtagg tatattaatt tcagtgtttg
     1081 gagcattaaa tggattttta ctaactggtt caagggtggc atatacttta gctacagata
     1141 agactttacc aaagtatggt atattttcta aattaaattc tgctcaagtt ccagcaaatg
     1201 caatagcatt agtatctgtt attgcatcta tatatgcttt gtcaggtcaa tttaatttat
     1261 taactgactt agctgtattt gctacttgga tattctatgt attaactttt ataggggtta
     1321 tgaaacttag aaagactcat ccaaatatac caagagagta taaagttcca ttatatccta
     1381 ttgttcctat aatagctata gcaagtggta tatttgttgt agttaatcaa ttgtgttttg
     1441 caggtatgaa aactactatg atatctatag gaggtcttgt aataacagct ataggcttac
     1501 cagtgtatgc ttatatgact agaggagtaa aaagataaac caagtagttt acaaatgctt
     1561 cataattaaa ataaaagaga ctgtctcaaa tagagataag tctctttttt attgttaaaa
     1621 tggtaaagat atgtttaatt ttacaaaaaa agagcgttcc atgaactaaa aagtttattt
     1681 taaggtattc attttatttt tagttttttg attataaaat taaacatcta aaaaattatt
     1741 tattttaaaa tactttattt taaagtgttt tttatcaaac taagtggtat ctgtacaaca
     1801 aatattatac atagctttta tgaaaattaa atctttctgt tatatataat agaatattgt
     1861 attatataga aaatattacc tgattaatat agtgatttat aaatgagatt agaaaatttt
     1921 atttgataac aaaaattaga taatatgaat atataatgta tgtattaaaa atgtggcaaa
     1981 tagttgtttt gctatttatt atttgtttaa tatttctaat ttataaaaaa aaaattataa
     2041 attttaaaaa ttataaatga cattttaact agaattaatt gtaaaaaaca ctatataata
     2101 ctcaattttc aacattctat acaattatac agaaattata cagcataata atcaccgaaa
     2161 taacaaattt taaaaattaa gcaaaacttt ttgtcgaagt tcaacgtcta tatatatgta
     2221 gtgtaaattt ttgggataaa atactacaaa aatataaatg taaaaatata gtaatattgg
     2281 aggtcgaacg atgagaaata aaaagaaaaa aataaataga aagaagttgt atttgctttt
     2341 aagtgctatt gtagtgtgtc tggcttttat agtagttggt gttcgcgtca gctctttaaa
     2401 tatgaaggaa aatgaaatta gtagaaatgc aaaactgtca agttctacta ttacagatat
     2461 agtatctaat acatcaatag aagttagtaa agggccaagt aaaagttctg gaaaaatagc
     2521 atacataact atagatgatg gtccatctaa atttactgac cagatgataa aaactttaaa
     2581 taaatacaat gttaaagcaa ctttttttat gatagatggg aatatgaagg aatatccaca
     2641 gcaagttaaa aatataatta aaaatgggaa cacagcaggt tttcatagtg tatcacatga
     2701 tattcacaag ctttatgtta ctagtacatc agcaaaagag gaatttgata caaatgatca
     2761 aactttttat aagataactg gtaaacattc aaaagtaata agaatacctt atggaagcaa
     2821 accatataca ccacaagcct cttatcaggc tttagttgat gctggatata aaatttggga
     2881 ctgggactta gatacagaag actggagatc taattcttct caaattgtac aaaatgtaaa
     2941 aaatcatatt aagaatagaa aaggtgaaga taaagaccaa cttgtagttt taatgcatga
     3001 gaaaaaacag agtgcagaag ctttagattc agttttaaaa ttcttatcag atgaaggtta
     3061 tgaatttgcg ccagtagatc aaaaccaaat accaaaaaat tattggttac gtaatttaga
     3121 gtagttaaaa tataagaata ttgattgata tttttagaaa ttgagaataa aaatgagtga
     3181 ggtgtaggta tattgaataa aaaactttat ataggaatgg tcggaatatt gtctttgatg
     3241 atggttggtt gtaataaaag tttagcaaaa gtaaatgatg tggaaatcac aaaagaacag
     3301 tacaaaaaaa caaaagcagt tttatctgct actaataatt atataaatgg gcagtcttta
     3361 gatgaattag aaaaaacttt ggataaaaaa ggtagaaata aattagaaaa tgttataata
     3421 tcgtttatgg tggataatga acttttatat caagaggcta aggataaagg actaactcca
     3481 agtaaaagtg aagtagactc aaaatatcaa gaactagaag ataagatgaa tttgaataca
     3541 agctataagg aaaaaatgga caaagcaggt gttgataaag attatttaaa acaagaaata
     3601 tctagagatt tagcaataga taaaaataaa aaggcctttg aagatagaat aaacataagt
     3661 gataatgata tggaagccta ctatacaagt cataaaaaag attttaatgt agaagaagta
     3721 agtgcttctc agatacttat atcgacttta gataaaaata aaaaagaagt aagcaaagat
     3781 aaaaaagaag ctttgaagaa gaaggcagat aatatattga ctaaaatcaa aaatggagaa
     3841 agttttgaaa gtttggctaa aaaatattcg gatgataaag caactggaaa aaatggagga
     3901 cagctaggat attttacaaa ggatgataaa aatgctgagt ttacaaagga agtgttcaaa
     3961 ttaaagaaaa atgaagtttc aaatgtgttt gaaactagtt atggatatca tatagtcaaa
     4021 gttactgata aaagagaaag acaaaaaagt tttaatgagt gtcagagttt aataagagaa
     4081 tctattttaa atgaaaagta tattgagcat ataaaaaaac tgaatgaaga tgctaaaata
     4141 gacagataga atttctaaca gctcaatcct agcctgtaat cggagggaga ttttacagga
     4201 atgtttaaga gtttaaagag aacgaaagtt gagaaataca ttatcgataa taaagactct
     4261 ttttatagaa tagcatatag ttatacgaag aatgaagaag atgccttaga tgtggttcaa
     4321 gaagccatgt ataaggcact atactcagtg gaaaatatta aagaagtaaa ttatataaag
     4381 acatggtttt ataaaatttt agttagaacg agtatagatt ttattagaaa aaaccgtaaa
     4441 tataataata tgacagatat tgaccttata gatgagactg gagagtatga taaatatact
     4501 gatttggatt taagaagagc tttggaagaa ttacctattg aatacaaatc tattataata
     4561 ttaagatttt ttgaagattt aaagattgaa gaagtagcaa taatattgga tgaaaatgtg
     4621 aatactgtta aaactaggtt atatactgct ttaaaaaaac taaaattaaa aattgaagag
     4681 tagggataaa aagaatgaca agcaaagaaa ggttaaataa gttaaaagat gagtatcata
     4741 aaattccaat acccaagaaa ttagatacta taataaatca tgaaaaaata gaaaacatat
     4801 atcgagagaa aaataaaaaa gtaaatagat taagatttaa agttgcaata gcctttgcat
     4861 gtatatttac agtattagta aatataagtc ctgtatttgc agacaatttt tctaagatac
     4921 ctgtaattgg agcaatagta gaagtaataa ctataaaaaa ttatagttta aaaagtgaaa
     4981 attatgaagc tgagattgat attcctaaaa tacgaggttt aaaagataaa aacttagaac
     5041 aaagattaaa cagtagtttt atggaagatg gaaaaaggct ttatcatcaa ttccaagaga
     5101 gaatggagaa gatacaatca tcaaagaata aaggatataa atctttaagt ttgagttata
     5161 gtgtaaaaaa taattctaaa aaatttctat caatagagat gacaaaaaat gagatagagg
     5221 cttcatcata tgtgagtaag gtacattata ctattgataa aaaaagacaa atagttttga
     5281 ctttgccaat gctttttaaa gatgataagt atataaaagt tataagtgat aatataaaag
     5341 aacaaatgag agaacaaatg aaaaaggata gtacaaaatc ctattttata gatcaaaaaa
     5401 aagacttgcc tgttgaagat tttaaaacaa ttaataagta tcaggatttt tattttaata
     5461 aaaatgaaga ccttgtaatt tgttttgatg aatatgaagt agcacctggt tatatgggtg
     5521 cagttgagtt tgtaatacca tataaagtaa taaaagattt gtaaattgaa tagtagttta
     5581 tatataaatc ttttaaggag gacaatatga ctacatataa aaaacttaaa aaatctatat
     5641 ttaaaattgc tatattttca atatgcttat tagtttcatt agtagataca aaccctatat
     5701 ttgcaggtag ttcatttaat gaaacttcaa atagtgatac gataaaggtg ttaaatgcta
     5761 agagtatcaa ctttaaacaa gacaattatg aagtgaatgt gagtattcct aaaataaaag
     5821 gtttaaaaga taaaacttta gagaataaat taaacaatga gcttttgcaa gatgggaaaa
     5881 aaatttacag tgaatttcaa aataaaatga aaaaggaaaa taataagggt catagatacc
     5941 taaatgtaat ccataatgtc aaaaataatt ctaaggactt tttatcaata gaaatgacaa
     6001 aagaagagat agaagcttcc tcatctataa ctaagaagca ttacactgtt gataaaaata
     6061 gaggaatact attaaattta ccaatatttt ttaaagatag tagatatatt aaagctataa
     6121 gtgataatat aaaagagcag atgagaaatc aaattaagaa agatgataca aaatcttatt
     6181 ttatagacca agataaagac tccccagtga aagattttga atctataaat aagtatcaag
     6241 atttttattt taataaaaat ggaaatcttg tgattagttt tgatgaatat gaagtagcac
     6301 ctggttatat gggagcagta gaatttgtga taccaaataa agtaataaaa agactaagat
     6361 agatatatag aagattttta gatagactgg taaggagaat tatatgaata tatatgaaca
     6421 agcaataaga ttaatagaaa ataatgagga tttcgcattt gctacaataa cgtctcattc
     6481 aggttcaaca ccacgtgaaa ctggagcaat gatgattgtg aaaaatgatt ctactatatt
     6541 tggctcagta ggaggaggta gtgtagaagc agaatgtata aaacatgcaa ttaatgttat
     6601 aaaaaacaga gaatcaatgt tgtataaatt tactctaaac aaatctgatg tggcaaaact
     6661 aggaatgata tgtggaggta ctggagaaat acaaatagat tttatagata gtaaattaaa
     6721 aagtaatata gaaaaattta ataagagact aaaggaaaat acaagtaaag catatatatt
     6781 tggtgcaggt catatttcaa gagatgttgc tgtgatacta tctcttttag aatttagaac
     6841 agtagtaata gatgatagag aagaatttgc taatcatgaa aggtttccag aatcagaagt
     6901 agtagtttta gattcttttg aaaacatacc agattttcca actgacgaaa atagttatat
     6961 aattatttta acaagaggtc atctatatga ttcaagtgct ttagaatggg ctcttaaaag
     7021 agaggctggt tatataggta tgattggaag tagaacaaaa attggattga cttacgaaaa
     7081 actcatgaaa aaaggtttta agaaggaaga attatcaaaa gtacatgcac caataggcat
     7141 aaaattgaat gctcaaacac cagctgaaat agctgtatgt atagctgctg aacttataaa
     7201 ttgtagagct aataaggaaa aataaactaa tgaacacagg gagtaaagat attgatactt
     7261 taaaggttaa ttttagaggg attgaaataa aagcagtttt agtatataaa aatagaaaaa
     7321 atatttctat aaaaatagat ccatttggca aaataactgt aatgagtcct cctaaaatat
     7381 ccaaaaaaat aataaaagat ataattattg aaaaaggaga ctggatactt aaaaagtcag
     7441 aaaaatgtaa aggaagagag gaagtatata aacaaagaat gtttataact ggcgaaaaat
     7501 ttctttattt aggtgaagag taccatctag ttataaaaga actgttgaga gattctgtca
     7561 aaaaaagtaa ctgtagaata actattaacg aatatcaaat agttgttcag acaaatgata
     7621 caagtacaga ttttattaaa aaatctttaa aatcttggta taagatggaa agtgaaagaa
     7681 tagtattaga gagaatagat tttcttaaat taaattgtga aataatgaag aaattagttc
     7741 cagcaagtgt taaggtaaaa gaacaaaata agagatgggg aagttgtaca gctcaaaaaa
     7801 atatttatat aaactcaaaa atatctatgg caagattaga tgtaattgat tatgtaataa
     7861 tacatgagtt tagccattta gtacatatga atcactctaa aaaattctat gatttagtaa
     7921 aatccattat gcccgattat aaagataaag aaaattggct aaaaataaat ggatataaaa
     7981 taataatctg aaaacgatta ttccaaaata taggcgtaaa gtataaaaga agtattattg
     8041 tgaaaaaaat aaataatctg aaaattttaa aaaaagtcat tgacattgta aatgataggg
     8101 aatataatct atattaacaa caaaacagaa ttaaaatata aaattaaaaa attaaaagca
     8161 atgacagaga caacaatact aatagtgtta tccacagaga accaatgttg ctgagaattg
     8221 gtgttaacag tagtataatg atcactctgg agcttttgta ctgaatattt ttagtaagta
     8281 caaacgtatg tcaacgttac atgactaagg ttaaggtaat taattacccg acctgaaaaa
     8341 agaggggtag atgtattttt tatatctaca aataaggtgg taccgcggaa tataactttc
     8401 gtccttataa gtaatattta tattgcttat aaagatgaaa gtttttttat tttaagcgat
     8461 ataaataaat ttaatccata taaaattaat aaaaaaataa taaaaataag gagggatttt
     8521 tatggaaaat actgtatatg ctaaattaaa ccaaggaata gattcttttt taagagtggc
     8581 tatgactcta agaagaagag aggttgatat acaatcaata agtatgactg tagataatat
     8641 gaataattca ggtataaaat taatagtaaa tgaagaaaag acatctttag attctgtctt
     8701 aaaccatatg aaaaaactac atgatataag agagataact gttgaaagaa tgagacatta
     8761 attaaatata ttttataaaa ctaaagataa atatgcttat tttaaaataa aaaactaaag
     8821 ataaatatta aataagaaaa atcttagatt aaaatataag tgtcattgaa tttattagtt
     8881 tatcacagtt aataaattta ttagtttgtt gtagctaata aaaactgaaa attctaaaat
     8941 tataattgta agattatata aatttagaat ttaaatctgt tgaataatat taaaacaatg
     9001 ataatgagta tgaatttcta ataaaaataa atatcataaa aataagaaaa agtattggga
     9061 ggaaatgaaa atggcaagaa tgtattatga aaaagatgtg gatttagagg ttttaaaaaa
     9121 taaaaaggtt gcagttttag gttatggaag tcaaggacat gcacatgcac aaaatcttag
     9181 agataacggt gtacatgtaa tgataggtct ttatgacgga agtaaatcag cacaaaaagc
     9241 aaaagaagat ggatttgaag ttaagagtgt agcagaagct acaaaagaaa gtgatttgac
     9301 aatgatgtta atgcctgatg aaaaacaaaa gaaagtttat gaagagagtg taaaggataa
     9361 cttaaaagaa ggtcagacat tagcttttgc tcatggattc aatatacatt ataatcaagt
     9421 acaaccacca gaatttgttg atgttgtaat ggtagctcct aaaggacctg gtcacttagt
     9481 tagaaatgta tttacaaagg gaagtggagt tcctgcacta tttgcagtat atcaagacta
     9541 cactaaaaaa gctacagaga cagttttagc atatgcaaaa gggataggag caacaagagc
     9601 aggtgtttta gaaactactt ttaaagaaga aacagaaaca gatttatttg gagaacaatc
     9661 agtactttgt ggtggaataa gtgaacttat aaaattggga tataaaacgc ttgtagatgc
     9721 aggttatcaa aaagaagtag catattttga atgtttacat gaaatgaaac taatagtcga
     9781 ccttatatat gaaggtggat ttgaaagaat gagatatagt ataagtgaca cagcagaata
     9841 tggagattat gtatctggta aaagggtaat aactgatgct gcaaaacaag gtatgcaaaa
     9901 tgttttagag gatatacaaa atggaaaatt tgcaaaagcg tggattaaag aaaatgaaga
     9961 aggacgtgaa aacttcctaa aaactagaga agaagaatat aatacagaaa ttgccgaagt
    10021 tggtagaaat ctaagaagta tgatgtcatt cttaaaataa atatatatta aatggattag
    10081 tttgagggaa agagtggtgt atagtagtgc gtatgaatgg agcaaaggta attttagaat
    10141 gtttaaagaa agagggaatt gacacaatat ttggatatcc tggtggagcc gtgatacctc
    10201 tttatgatgc tctatacgat tattcagatg attttaaaca tataaggaca tcccatgaac
    10261 aaggtttagt tcatgctgca gatgggtacg caagaagtac taatacagta ggagtttgtt
    10321 ttacaacatc tggtccagga gcaacaaatg ccataactgg aatagcaaca gcttttatgg
    10381 attcttcacc tatggttgta atttcagggc aggtgccaac tagtttatta ggaaaagatt
    10441 cttttcaaga aattgacata actggagcaa cattatctat gacaaaacat aattatttag
    10501 ttagaaacac taaagaatta gttcctacaa taaaagaagc ttttagagtt gcaaattcag
    10561 gtagaaaagg acctgtactt gtagatgttc caaaagattt atttttagca gaaatggatt
    10621 ttagtggtga ggactatgat ttatgtcaaa tagatgatta tatggattat aagagtgatt
    10681 ttgatctaga tgatgaaact aatattaagc ttttaaatga agcaatagat atcataaaag
    10741 aatctaaaaa gcctgtaata tatgcaggtg gaggtgttaa atcttcagac agtgaggaaa
    10801 ttcttgaaaa atttgcaact aagatagata cacctgtact aaatacactt atggggcttg
    10861 gaaatataga tagaaagaat gaactatctc ttggaatggt tggaatgcat ggaagtagag
    10921 aaagtaattt agcactttct aattcagatt tagtgatagc gataggtgcg agatttagtg
    10981 atagagtgat aagtaaaagt tctgaatttg ctaaaaatgc aaaaataata cacatagaca
    11041 tagacccatc tgaaataagt aaaaatatag aatctaatgt atctttggtt ggagatgtaa
    11101 agctagtcct tagtttatta attgaaaggg ttgaaagtaa gaataatagc aattggaaag
    11161 aagagataaa gagatttaga aagagtgagg gtgtacaaac atatgaattt catccacaaa
    11221 atatacttaa aaaaataaat gaaaaatatg aaacattaaa gaaacccact gtggtagtaa
    11281 ctgatgtcgg tcaacatcaa atgtgggctg ctaagtactg gaattttaaa ggtaataaaa
    11341 gttttataac atcagcaggg ttaggaacta tgggatttgg tttaggtgca gctattggaa
    11401 ctaaagttgg taatgtagat aaaaatgtag ttttagtcac tggtgatgga agttttagaa
    11461 tgaactgtaa tgaactagct acagttgcaa attataatgt acctatgctt attttactac
    11521 tcaataatag aacattagga atggtaaggc aatggcaaaa gttattttcc aatcaaagat
    11581 actctcaaac tgacattaat gaaaatgtgg attatgttaa actcgtaaat gcatataata
    11641 ttgatggata taaggtatcc agtatggaag aattaggaaa ggcgctagat ataatagatt
    11701 ttaataaacc tgtatttttg caatgtgata tagataagga ttatgatgtt tatcctattg
    11761 tagcacctaa tgatgcattg gaaaatttga tatgtaacta aaacttatac tgaatattga
    11821 taaaattttt tattaaattt ttattggtat tcaggttttg tttagagata gattggcatt
    11881 ttttattttt gcaaataaat caatgactat ataattgaga acttattaaa ttttaattat
    11941 acaatttgga atagtattac aacttaagta aatattaagt tttatttgtt agatttatta
    12001 ttaatacctt atattagtta tggttgttat atactctaaa gccttgaaat tacaagtata
    12061 tagatgatta tataaatttg ataattttag cttttaaaat agataaatta gattttgcca
    12121 cccatttgcc accgtattat atttttgggt ggcaaactct aatttgtaat tttttcaaat
    12181 atatctacag tttcattttt cattttatca gttacatgtg aataggtatc cattgtagtt
    12241 gatagttggc tatggcccaa acggttttgt atgtctttaa tgttagcacc attttctaat
    12301 aatagagtag catgtgcatg tcttaaagaa tgaaaatgga agtcattgtt taaagctact
    12361 cgaatttgtc ttactatagt gtctaaagtg tgagtattca cttgttgacc attttctttg
    12421 gtacataccc agtcactatc aaagtaaaat tctccatatt ttaatttcat tttcttttga
    12481 tataatttat gttcttttaa tgcctttatt aaagtgtcac ctgtaaatat agttctgcaa
    12541 gagctttctg tttttggttg ccctaattca aacattccat ttggtttttt aatcaaagta
    12601 tgctttactg tgatagtttt attatcaagg tctatattat cccattttag tgcaataatt
    12661 tcacctcttc gcataccagt atgaaatcca attagtaaaa ctatacgttg aaatgaatct
    12721 tgaggaaata tatttagtat ttgattaaat tcttctaatg taatagtttt aactttatta
    12781 gtttctgttt tagatttagt ttttggtatg cttacatatt gcatagggtt ttctcgtatg
    12841 tgtttgtaag gatggactgc tgattttaat gacctatgta atatggcttt taatacttgt
    12901 aatgtatttt gagagtaatc ctctttgtac tttttgttta tgaagttttg tagtattgca
    12961 ggagttaaag cttttacttt gtaagctcct agctttggtt ttatgtgttt ttctatgttt
    13021 attcggtagc tttcttgagt gttgtattta cagttaagta agacatattc tttgtaccaa
    13081 aagtctaagt agtctgataa actgatgttg ctttcttcaa atactatgcc agagttttca
    13141 tattcattta gtgcttctct taaggctttt tcggcttctt ttttagtatt gcctccaact
    13201 ctttctactt tttttctttt tccttctact atgcctaggt caaagtagta ataccatttg
    13261 ttacttcttt ttcttactcc acctttcata atagtatccc tcccttttag aatgtatgtt
    13321 tgtttggtgt ttatataaaa gagcagatta actgctcttt atatactttt gttatgtaca
    13381 atattatctt aattttgttt atctggtttt cacttaatca ttttcttaat attcttacaa
    13441 ttttttagct tttatgtgta gtttattata ataatattga aatatatatt tattaagtaa
    13501 aaaatctata aaagtagaat aaatgagttt aaaaaatatc ctcatatatg tagaaatttg
    13561 gcaaattagt taatactaaa aatctattat ttcctaagtc caacatgctt ttcttttttg
    13621 atagaaattc taatcttttt agtaagaagt tgatgctaac ttgtaattct tcagctattt
    13681 cgtatacact tgtagcgtgt gaattaataa catgtattat ttcttcttct gttataagaa
    13741 attcacatgc ccattttaat gctttgtttt cagttttgtc tatcaagatt ttatttttgt
    13801 aactgttttt tgaagataca tagttcccaa cactggtaaa atgatgtcct aattcttctg
    13861 ctaagatttc tattagttta gcattgtttt gttttaatga attaagtaat gatataatct
    13921 ttagtccttg tctgtttata tacaatcctt ttatgtcatc tgctattttg tcagtgtagt
    13981 aaatttctat ctcttcatta tttgctaagt ctaaaagtgc gtctagtttg ttcattgaaa
    14041 tccccctata aaaagaatgt atttttgatt tttgttatat ataaagagca ggtgtgaacc
    14101 gctctaaata ttcatttttt atccaaaaaa gattggataa ttttagctgt agacaaaata
    14161 tggattatag tatatgatta taatataatt acatataata tatgtaagca cttacaaatg
    14221 tgtgttagta tagttagcac taaatttgta tttgtgctta aagcgattaa aggagttttg
    14281 gagcggtggg tagagtttta ctcactataa ccaagactct tttgcatatt agagtatttc
    14341 atgtagtcat atattctaat aagccttctt aaatttgttt tttcgcttgt ttttgcagac
    14401 tctaaaatat taggattttc ctcaaatatt ttcttaagta gattttctaa ctgttcagtg
    14461 tcaatttctt tttcttctaa aaaagcaata agtcttgtag ctttttcaaa tgattgatgt
    14521 tcatcattcc aaataccata aacacttcta ttttttatgt aagtattatt tctatttttt
    14581 ttaatactat tgctaataat attttcaaag tcactttcta gtgcaattgt cctataatct
    14641 ggaaattcaa gtgtgctatt aaaaagatgt ttatttaatg gtaatttatt atattgctta
    14701 attaaagatg gataagcata ttcaagtaat tcatctgatg aaaattctaa gtcattcatg
    14761 actatatcac gataccattc atcaaaactt aatcctttta atcctttaag accaaaatca
    14821 cttgccttgc caactgctaa aactaaatct tcatctttta ttcttgtatc atcaacacta
    14881 ccaacccgaa ttttagcagt aggtttgtta gtaattgtga aatcgtaaaa ttcttgtttg
    14941 aacattctta atattctaac tggtaatttt gatttttttt cagataatgc ctcatagagt
    15001 aaattaaaat cctccagttt aattttagtc atagtaatca ttttattatc aaaagcaatt
    15061 gtatgacttg atatttctat atcattaaag tttttttcat actcaatgaa tatgaaacgt
    15121 tcctcgagtt ttttagcatt ttcattagat agacaattaa ctatagcatt aagtattttt
    15181 tttatattta catctgtaac agagtaacca ataaatatga taggaaactc aacaaatata
    15241 gtcattagct tagctgccaa gtaggcactt ttgctgtcaa agtctatata atcagcttca
    15301 tttattacaa tactatttgg agaagaaaca catccatgaa ttttataaat ttctgcaata
    15361 ccttgtatag atgaaaaaac taaattttct tgacctatat atgttgtata attatcaacg
    15421 atagtttcca aaaaacaatc ataatttgtt gtaataaatc ctgataaact ttttttagag
    15481 atattactaa gtttttcaac ttcatcttga tatttatcta ctattttaga attattttta
    15541 atatacatag caatttctgc cttaaatgga gaaactcctg atttaacaat atctaaatac
    15601 ttagagtcta agcttcgtat agaagaatct gaaaaccatt ttttattaaa atcattttca
    15661 ataagttctg caattctagg atttataccc atttttgggt tctctgattt tgctttattt
    15721 ttataacttg tatatataaa gtcatcatta ctaatttttt ctgcaaagac ttttagtaaa
    15781 tcctcccaat ttggaagatt atagtatctt ctagttaaac cagaaccaac aaataaaaat
    15841 ggtgtagcat taaatcggtt tatgacatct gatattatag atttcatata atttatcacc
    15901 tacttttaat ttatttttta tacttattta ttaaaaattc aatataatca ttgagttgtt
    15961 cttgagcttc ctctggtaaa tctttgtgag gattaactct atgtgcagct acagtgtcta
    16021 tatcattttt tacaatagac ctacctaata aataatcagt agtcacatta aatatttcag
    16081 caaggctaga taacatataa gcatcaggaa ctgtctttcc ttgttcataa taaccataag
    16141 cgcttttggt taagtttaat ttatttgcaa catcttcttg agtcatattt ttttcagctc
    16201 taagttcttt tagtcttttt tgaaataatg tattattaca agaagttttg ctagaaatat
    16261 tgcttgcttt attatcatac ctacctatta aataatcaac agtagtgcca aaatattcag
    16321 ctaaactaga taacatttct ggggtaggtg ttcttttacc ttgttcataa aatccatatg
    16381 cactagtagt tatgttaaga tagttggcaa tttctttttg cattacacct ttttctttcc
    16441 taagaaattt caatctatct gataaaatgc tcatataatc actcctctta ataaagttgc
    16501 ctttattaaa taatacaaca aatagttgta aaatgaaata aaaaaataaa aaaactattt
    16561 acaaacaaca tatagttgtg tattatataa gtataaacaa caaaatgttg gtaaggagga
    16621 tatagcttga acaatctaaa ggaacttagg acagaaagga atttaaagca aaaagatgtt
    16681 gcattaaaag taggtataac tactagttat tatggaatga ttgaaagtgg aacaagagta
    16741 ccaagtttag caatagcaat aaaattatct aaatgttttg gagtatcaat agaaaaaatt
    16801 tttttaaata caaatacaac aagatgttgt ttaaaagaga ggagttaaat atgaaagatt
    16861 taaaaatagt aaaagttaat aataaactaa caactgacag tagagatata gctctaatgg
    16921 ttgaaaaaga acacaagatt ttactaaggg atataagaaa ttatataaac caaatggaag
    16981 aagccaataa aaacatgagt acagatttgt acccatctga ttattttatt gaaaatactt
    17041 atttagatga ttataaaaga gagaagccat gctatgcaat aacaaagata ggttgtgact
    17101 tcatagcaaa taaaatgaca ggcataaaag gtacggcatt tacaggaata tatacaaaaa
    17161 aatttgaaga aatggagcaa gtattaaaaa atgaacaacc taaactacca actacatata
    17221 aagaagcatt acaacatctt atagagcaag tagaagtaaa tgagaaatta caactagaag
    17281 gaaaaatgaa agaccaagta ataaaagaac taaaaccaaa ggcagattat acagatatga
    17341 tacttaaaaa caaaggactt gtcacaataa ctcaaatagc aaaagactat ggaatgagtg
    17401 gaaaagaaat gaataaaata cttcatgaaa gagggattca atataaacaa agtggacaat
    17461 ggcttttata taaacaacac caagggaagg gatacactca ttcagaaaca atagacataa
    17521 ctagaagtga tggaatgact gatgtaaaaa tgacaactaa gtggactcaa aagggaagat
    17581 tgtttttata tgacttatta aaagtaaata acatattacc agatatagaa aaagagtata
    17641 gttatcaaac ttcaatgtta tgttagtact ttgaaaaata aatacagaat attcaaaaag
    17701 aggtgattta aaggttgagt aatagaaaga agtatacctt gagtattacg aaagaattat
    17761 acaataaatg taaagaaaaa gctaatcaaa gaggtatgtc agtgaatgat tacatactat
    17821 cagtgattag caagagtata taaattattc ttcaatatta attttaattt ctccttttct
    17881 ttgctcataa tcttcaatat gtttttttat tatttgttca atttccttat tagcagaacg
    17941 accttcgctt tcagctatat atttaatttt ttcaagcaga actctgttta ttcttaaagt
    18001 gtatttaggt agtgaagttg acataataat acctcctttt taaagtctaa atgatgtcat
    18061 aattatatca taaaaataat ttatagaaaa tctataaaat atattgacgg cataaagacg
    18121 gcgtgatatt attaaaacaa gaaaggggtt gacggcaaaa tgaactcaaa taaaaagaga
    18181 ataactgtta ggatgccaga aaaattaaat gaagaaataa cgaaaaaatc aaaatactta
    18241 gggttaacta agaactcatt tatattagat atactatgga aggaatttga gttattagaa
    18301 tatagaagtt ataaaaagga ggtagataaa catgaataac ttacaagtaa tagaaagaaa
    18361 taatgagaga gttctaacta cacaacaatt agcagatgta tatgaaactg actcaagaaa
    18421 tataagtaac aatttcaaca ataacaaaga taagtttatt gaaggtaaac attatttttt
    18481 attgcaaggt gatgatttaa agaattttaa aggcattcat acagaatatg aaaacctaaa
    18541 atttgcttca aaaatgtatc tttggactga aagaggagca aatagacact gcaaaatatt
    18601 agatacagat aaggcttggg aacagtttga taatttaga
//
LOCUS       DAEORM030000069        17200 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.070, whole genome shotgun sequence.
ACCESSION   DAEORM030000069 DAEORM030000000
VERSION     DAEORM030000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 17200)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17200)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 17200)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17200
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.070"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            298..2310
                     /locus_tag="KRH23_003214"
     CDS             298..2310
                     /locus_tag="KRH23_003214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54 interaction domain-containing protein"
                     /protein_id="HHS5226488.1"
                     /translation="MKKSVALVNDSRKDLIDFLENNLKLVFGDSININRYFINEINDN
                     DLINDDVILVMSVERLDKIINNILDKKKVIVVRRTFREDKIYNLLSLPQGTNVLIVND
                     SDETTLETISLFYKIGVTNIRPIPYMNDNNYKNIKIAITPGVPEKVPSFISDIFDLGH
                     RYIDISTFIEIINLLQIDSKEIQSNLVKYSEEIISLDTGIKDKYKELFLKIEELDTIL
                     NLSKDGILFTSKDGEINTYNSKVKDILDINEDIYGKYIEDIFVDSLKVLLSEKEILDK
                     VVVFNKKYINVNKKNIYNRDEKMGTYYSLQEITYIKKLEQNLTKKLREKGQIAKYTFK
                     DIKTNSPKMFECIDLAKKVSKSDLSILIRGESGTGKELIAQSIHNNSNRKNQPFIAVN
                     CAAVPENLLESQLFGYDKGTFTGGLKDGKQGLFELANNGTIFLDEIGDMPLELQTKLL
                     RVLQEKQIMPVGSHNVINIDVRIISATNKNLEQMIDNSQFREDLYYRLNTIPINIPPL
                     RERKEDILIIMEDLINKKLVITPEAKKLIQNYMWKGNIRELQNVTSYLNIMCEDIVLE
                     KDLPPNLRSSDNKNTSLKLKYSKNDILNILEILILNKESDVGIGRGLILKSLLDKNLQ
                     ITEGKIKKIFEYLKKEELIICSSGRYGSKITQKGEDFYNKLKYKGL"
     gene            2678..3898
                     /locus_tag="KRH23_003215"
     CDS             2678..3898
                     /locus_tag="KRH23_003215"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M20 metallopeptidase family protein"
                     /protein_id="HHS5226489.1"
                     /translation="MQQALKLKYQTKELGKDFVIESCNSIKPWLINIRRELHKIPELA
                     LEENLTKQKVISYLKEIGIDYMEFTKHNGIMAYILKESADKTICIRADMDALPIEEEN
                     NIPYKSIHSGKMHACGHDAHTTMLLGACKVLHSIKDKLNVNVKFLFQPAEEGFGGAKF
                     LVEDGCLENPKADYIFGLHVMPHIETGLIETKYDTLNASVDTIKISIKGKRAHGAYPE
                     NGIDAIVTASQIVTSLQTIISRNLEPNNAAVLTIGKIYGGDAHNVICEDVKLEGTLRT
                     LNSKTRNFMIDKIAKIVGDTASAFGCVGTLHISDENYPAVINEKELVDTVISSTKELL
                     GEEKFILRPNPSLGGEDFSFYTEHCKGAFFHLGCKNEKKGLISPLHTSSFNIDEDCLP
                     IGVMMHVMNTLYFN"
     gene            3935..5284
                     /locus_tag="KRH23_003216"
     CDS             3935..5284
                     /locus_tag="KRH23_003216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015171 - amino acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HHS5226490.1"
                     /translation="MEKAKKLGLFSMILLGINSIIGSGIFLLPGKVYNLAGQNSMFIY
                     IFATLLVLSILLCFAEVGSMFDKNGGAYLYSKKAFGDFIGFEVGTMSWVIRIISWSTL
                     AVGFATALGSFWPESATEYKGYIAAILVTLLSINSLFGIKSTKIMNNVITIAKLVPLI
                     VFIIVGIFFIKFVNIVPSGNVVNSSMGPAIILVFYAFTGFESFIVASGEMENPKKNLP
                     IALITTIFICAIIYILIQIVCMGILGDRLFENSIPIADASSVFLGNYGKVFISVATLI
                     SIFGINIGSSIVTPKCGSSLAEEGSLPAFIGKTNKYGAPYVAIIISLICCIPLVLTGS
                     FEQLAVMSVIARFAQYIPTCLSVIVLRKRTDVKASFKIPFGPVIPMVAILGSLWLLQQ
                     AWAEDISKPITQNRVLIGLGAMLLIAPLYIFMKKNKEIEHKNKSEDSKLYISREKIQ"
     gene            5398..5961
                     /locus_tag="KRH23_003217"
     CDS             5398..5961
                     /locus_tag="KRH23_003217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226491.1"
                     /translation="MGLTKDILVPFKAKTYPLFRDEKYLFYIYLDKSGRIAATTDIDS
                     YLETDHTYNVGDVVNGVVYGFQTNNSAMICVDNKYAGVILHNEYFTELKAGDVLENLH
                     VIKIYDDGKLGFSPRGNRKDELDTLENKILSYLEGSDGYMRFNDKSDPKDISILFNSS
                     KKNFKRALGVLMKKDLIYQDEDGTYLK"
     gene            complement(6051..8384)
                     /locus_tag="KRH23_003218"
     CDS             complement(6051..8384)
                     /locus_tag="KRH23_003218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHS5226492.1"
                     /translation="MRSYLELVPQYAKVHKKKNRTTILCIVIAVCLVTAIFGLADMAI
                     QCQKVQFIKDDGNWHIVLKNLNEEAISEISSRVDIAHYGRGQVIDNGEFKSKEILIQG
                     LDEDLAKQLGLEIIKGRYPVVENETLIDVDAVKSFNLKVGDFIKIKLADGRNKNYKIV
                     GEYSSLSSLRASDKHGLMLSILGTQAIKKSETYDYYYITFKDKVNIRKATSDIKNTFN
                     LSDKQIGKNEKLLSIIGQGDSDYSKPLYLTAGGLFILVLIASIIMIYNSFNMGVIERI
                     KFFGLLRCLGASKLQVKKFVVLESLILSVKAIPLGLLLGCIVTIISSIFLKYVNTELF
                     GSMPILKVSFIGIVFGIIVGFLTVILSAIVPAKKASGVSPLSAIRGNLMFKEILTSGK
                     ASKIANAGSSKIDVSMGINHAFSRKKSFILMTSSFAISIVLFLGFSVFIDFMYQALKP
                     IKPEAAHISIVDADFKSVLTKDDINEISNIKGIKKVYSRMMTDVEATYNNKEATSQLI
                     SYEKNQFDWAKKYLVKGEINEDKLESENIGLVEEGHGFNIGDKIYIKNGNSKKEIEVA
                     GILSSISFDVKDKYIGNIITSENTFTSITDIKDYIIIDTQVDEDAPEDLIQNIRNVLD
                     DNLEVRDKRQGNLEAKNSFYTMAVFVYGFVFIIAIISMFNIINSMNISVTSRINYYGI
                     MRAIGMSNKQLRKMVIVESSTYAVSGCLLGSVLGLILHRYIFVSLVTLKFHIDWQIPF
                     DLLFIIVVTMIIITLLAVRKPIKKICELDIIEVVNAQ"
     gene            complement(8381..9064)
                     /locus_tag="KRH23_003219"
     CDS             complement(8381..9064)
                     /locus_tag="KRH23_003219"
                     /EC_number="7.6.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHS5226493.1"
                     /translation="MDILVVNNLCKTYGNGYTKVEALKDVSFTVSKGEFVTVVGESGS
                     GKSTLLNLLGGLDTPTSGKIFVDGKEICSMKEEKQTIFRRRNIGFIFQSYNLIPELTV
                     EQNIIFPLLLDYKKPDTIYLDEVLTILGLKDRKSHLPNQLSGGQQQRVAIGRALITKP
                     SIILADEPTGNLDSKNSSDVISLLKVTAEKYNQTIIMITHNTNIASTADRILQVSDGM
                     LKDLGVNRE"
     gene            complement(9135..10376)
                     /locus_tag="KRH23_003220"
     CDS             complement(9135..10376)
                     /locus_tag="KRH23_003220"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HHS5226494.1"
                     /translation="MKVFSNKDIKIFFLVIISVLLMFIVVGQIVVINITNDYKSALLE
                     HDYNIAGYLNSMGVDKSKIPAVFTTNEDKYTLKGKEILNTARYDFGTDDSFMPSVKLF
                     QGKYIKTMFLYLFVFFTMIIFILYVYFFRQQNKIEEASYKIDSFMNGNINVRLNTYEE
                     GSLSKLFGSIDAMSTSLNTHILKEKQNKEFLKNTISDISHQLKTPLTALMMYNQILQE
                     ESHNSEIVENFVQKSQNELERIESLIQNLLKITKIDSKTIILNKASVNVKKLITKILY
                     SFETRAEKEGKSISIRGLENTNLFCDYEWISEALSNLIKNALDNTKENDKIMIEWVET
                     PITTIISVSDTGNGIHIEDIHHIFKRFYRSKFSKSNQGLGLGLPLVKSIIEQHNGTIT
                     VESNFLQGSTFTLSFLKLTNM"
     gene            complement(10387..11073)
                     /locus_tag="KRH23_003221"
     CDS             complement(10387..11073)
                     /locus_tag="KRH23_003221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HHS5226495.1"
                     /translation="MSSILLVEDDLSLIYGLEYSIQKNGFSVDVARTVEEALQIYKEK
                     NYDLLLLDVSLPDGDGFDICKRVREASNVPIIFLTASDEEVNVVMGLDMGGDDYITKP
                     FKLNELISRIKALLRRYNFTSENVTELKSNNITVKLLENRVFKNEIELELTTAEYKLL
                     CLLMKNKNIVLTRKNILDKLWDGNGSFVDDNTLSVYVRRLRNKIEDNPENPKILLTVR
                     RMGYKWNVIK"
     gene            complement(11311..11520)
                     /locus_tag="KRH23_003222"
     CDS             complement(11311..11520)
                     /locus_tag="KRH23_003222"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226496.1"
                     /translation="MSNFSQYIIFAILLASMGFVIQKIVYMHFSEIELSGNYSTTVRN
                     ISDISLDNDNEMFNRGNIENSILKK"
     gene            complement(11981..14488)
                     /locus_tag="KRH23_003223"
     CDS             complement(11981..14488)
                     /locus_tag="KRH23_003223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HHS5226497.1"
                     /translation="MKLNYIVKKYIMGNKKNTLLIIVSIVISTALFLIMNIISEDATN
                     LMINQAKNEFTLKHAQYINPKDEEIKYIENNTSIDKVGKSMLLGISDIGKGQTLQILS
                     QDKVAEELNDIYTLEKGKLPVAENEIAIDSWYIKQKKIKNPIGKRITLDYRRQGIDQE
                     DLYTGEKEFKITGILNSNPILKAQGTSIGLISNDCAIKNIPTKNKYDQIMFTFKKEKN
                     IQRQSQKLIKNGNLNENNIYFNNELLIAISDSMNLKIPYIIVNIVLALATILLIYNIF
                     YILVSNRIKDFGIFRALGFNPNDIFKIMILEVSIYSIISISIGLILGGIIASLSREYV
                     IGVIYNVNYINSIKNQNYINTYIISILLSLGTIIISVSKPLMLSVKTDPMICIRRNNE
                     KVDIKQNSFINKFMIKLFKDYGNIASKNIQRNKKRTNLSIASMVIIFFLMATIYTKST
                     SNFLSDGVLKYWIQGDYLLHNIDISTIRSNNKGYDKNVLQEIKAIDGVTKVNSYRHKW
                     FNIKIDDKSINKNSDYWKKNKDNIEARSEVKDGIKVYNNSFEFLGIEDTDILEDFLIN
                     GKENIDKFSKQPYLYITKKSSDSLNIKKGDRIKVYFDIIDSKTNNFTKTISQEFIVCG
                     IITTLPVTSQVGAEFGGVISTNQFNKFTGISSYERFDIWTSKLANDKYVESELNKITE
                     KTNKGILIPYKAETAEYEKIDNQKTLIMVLVTGIIVILSLFNCCNTIVTSINSRSREF
                     ALFRGIGISKHEINKIVKLESYIYIIVSFCISIIPILIVRSIIIKPFESINLINWKFI
                     GAIILIVFILVSIIMITTLKTLNKIQNENFMEEIKTL"
     gene            complement(14497..15159)
                     /locus_tag="KRH23_003224"
     CDS             complement(14497..15159)
                     /locus_tag="KRH23_003224"
                     /EC_number="7.6.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHS5226498.1"
                     /translation="MSILEIKNLNKIYGKSETEVKALSQINLKINSGEFVVIVGKSGS
                     GKSTLLHIMAGLETPTNGDVIIDNINISSLDEKKRSALRKEKLGLIFQSYNLIPVLTV
                     EENIKLPTINIKNKDEAYINELMELLGIKDRRMYLPNQLSGGQQQRVAIARALVNKPS
                     IVFADEPTGNLDTKTESDVLSLLKESQKKYNQTIIMITHNIDITKYADRVIEIEDGFI
                     RE"
     gene            complement(16290..16757)
                     /locus_tag="KRH23_003225"
     CDS             complement(16290..16757)
                     /locus_tag="KRH23_003225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HHS5226499.1"
                     /translation="MKFLNVLIVVEDIEKSKKFYYDILGLKVICDFGENVVLEGNISL
                     QEKKLWLEFINKSDSEVKFNGNDAELYFEEDNFDTFVERLSTMKDIDYVHLAIEHRWG
                     QRAIRFYDLDGHIIEVGETMSSVCRRFLDSGLSIDEVAKRMDVTVEYIESVLE"
BASE COUNT         6161 a         2453 c         1961 g         6625 t
ORIGIN      
        1 attctatatt tacaaaatta tattatcaat agaatttatt aaaataaatt tttttgggtg
       61 tatattataa tttaatcgaa tagaaatgaa aaatatacat acagtttaag ttttaagcaa
      121 caattagggg gatttggtga caagattttt aattataaga aagaaagtgt cttaatgcaa
      181 cttttataaa gtcattatag acactttctt ttttatttga taaatttaaa ttatcaaaat
      241 tatattgctt tatacaacta ttttgttgga aactatttat tatataagga gaaataaatg
      301 aaaaaatcag tagctctggt aaatgatagt agaaaagatt taatagactt tttagaaaat
      361 aatttgaaat tagtttttgg agattctata aatattaata gatacttcat aaatgaaata
      421 aatgataatg atcttataaa tgatgatgtg atattagtaa tgtcagtaga aagattagac
      481 aaaattataa ataatatact agataagaaa aaagtgattg tggtaagaag aacttttagg
      541 gaagataaaa tttataatct actatcttta ccacagggta caaacgttct aatcgtaaat
      601 gattctgatg aaactactct agaaactata agtttatttt ataaaattgg agtgactaat
      661 attagaccaa ttccatatat gaatgataat aactataaaa atataaaaat agctataact
      721 ccaggagttc cagaaaaagt acctagcttt atctcagata tatttgattt aggtcacaga
      781 tatatagata tttctacatt tatagaaata ataaatttat tacaaattga ttcaaaggaa
      841 atacaatcta atctagttaa atactcagaa gaaataataa gtttagatac tggtataaaa
      901 gataaatata aggaattatt tttaaaaata gaagaattag atacaatatt gaatttatca
      961 aaagatggta tattatttac ttcaaaagat ggtgaaataa atacatataa tagtaaagta
     1021 aaagatattt tagacataaa tgaggatata tatggaaaat acattgagga tatatttgta
     1081 gatagtttaa aagttttatt gagtgagaaa gagatactag ataaagttgt cgtattcaat
     1141 aagaaatata taaatgtaaa taaaaaaaac atatacaata gagatgaaaa aatgggcaca
     1201 tattatagtt tacaagaaat aacatacata aaaaaattag aacaaaatct cactaaaaaa
     1261 ttaagagaaa aaggacaaat agcaaaatat acatttaagg atataaaaac aaatagtcct
     1321 aaaatgtttg aatgtataga tttagctaag aaagtttcta aatctgattt aagcatactt
     1381 atcagaggtg aaagtggaac tggtaaagaa ctcatagctc agtctataca taacaactca
     1441 aatagaaaaa atcaaccctt tatagcagta aattgtgcag ccgttcctga aaatttatta
     1501 gaaagccagc tattcggata tgacaaggga acttttactg gaggtctaaa agatggaaaa
     1561 caaggattat ttgaacttgc taataatgga acaatattct tagatgaaat aggcgatatg
     1621 cctttagaat tacaaacaaa actacttaga gttcttcaag agaagcagat aatgcctgtt
     1681 gggtctcaca atgtaattaa tatagatgtt agaatcatat ctgctacaaa taagaattta
     1741 gaacaaatga ttgataatag ccaatttaga gaggatttgt attatcgatt aaatacaatt
     1801 ccaataaata tacctcctct aagagaaaga aaagaagaca tattaattat tatggaagat
     1861 ttaattaata agaaattagt aatcacacca gaagcaaaaa aacttataca aaactatatg
     1921 tggaaaggta atataagaga actccaaaat gttacatcct atttaaacat tatgtgtgaa
     1981 gatattgtat tagagaaaga tttacctcca aacttaaggt cttcagataa caaaaataca
     2041 tcattaaaac taaaatatag taagaatgat atattgaata tattggagat actaatttta
     2101 aataaggaat cagatgttgg tattggtagg ggattaattt taaaatcact actcgataag
     2161 aaccttcaaa ttacagaagg aaaaattaaa aaaatatttg aatatctaaa aaaagaagaa
     2221 cttataattt gtagttcagg aagatatgga agtaaaataa ctcaaaaagg agaagatttt
     2281 tacaataaat taaaatataa aggtctataa aattataatt tatcaaacaa agaaatctat
     2341 tcaggattaa agtactcctt caataggttt ttttattttt caagtaccct aaaattataa
     2401 tttattttgt acataaataa taggaattaa taggaatagg ataatttttt tatttcctat
     2461 ttttttatat aaactagcat ataaaatata ttttcttcaa aataatattt tttactgaaa
     2521 attgaaacta tgcaatcatt ttttatacta tacatataga taaatgatta tatttattca
     2581 atattcttat aaaaaacaaa gttctccatc gaaaattatg gcataataat tgcttattat
     2641 attaataaaa caataaaaag caattggagg aataaaaatg caacaggctt tgaaattaaa
     2701 atatcaaacc aaagaattag gaaaagattt tgtaatagaa agttgtaatt ctataaaacc
     2761 atggcttata aacataagaa gagaattaca taaaattcca gaattagctc ttgaagaaaa
     2821 tcttactaaa cagaaggtaa tttcttattt aaaagaaatc ggaattgatt atatggaatt
     2881 tacaaaacac aatggaatta tggcatatat tttaaaagaa agtgcagata aaacgatttg
     2941 tataagagca gatatggatg ctcttcctat tgaagaagaa aacaacatac cttataaatc
     3001 aatacactct ggaaaaatgc atgcttgtgg tcacgatgca catacaacca tgctacttgg
     3061 agcatgtaaa gttttacatt caataaaaga taaacttaat gtaaatgtaa aattcttatt
     3121 tcaaccagca gaagaaggtt ttggaggagc aaaattttta gttgaggatg ggtgtttaga
     3181 aaaccccaag gccgattata tattcggact tcatgttatg ccacatatag aaacaggcct
     3241 tatcgaaaca aaatatgata cattaaatgc tagtgtagac actataaaaa taagtatcaa
     3301 aggtaaaaga gctcatggtg catatcctga aaatggtatt gatgcaatag ttacagcttc
     3361 acaaattgtt acatcattac aaactataat aagtagaaac ttagaaccaa ataatgctgc
     3421 tgttttgact ataggtaaaa tatatggtgg tgatgcacac aatgtaatat gtgaagatgt
     3481 aaaattagaa ggcactttaa gaaccttaaa tagcaaaaca agaaacttta tgattgataa
     3541 aatagctaaa attgttggag atactgcatc tgcatttggt tgtgttggga ctttacatat
     3601 aagtgatgaa aactatcctg ctgttataaa tgaaaaagaa ttagtagata cagttatatc
     3661 aagtactaaa gaattacttg gagaggaaaa atttatattg agaccaaacc cgtctttagg
     3721 tggtgaagac ttttcttttt atacagaaca ttgtaaagga gcattcttcc atttaggatg
     3781 taaaaatgag aaaaagggct taatttcacc tcttcatacc tctagcttta atatagatga
     3841 agattgttta ccaataggtg ttatgatgca tgtaatgaat actttgtatt ttaattagta
     3901 cagtaattaa taaaagaata ggagataaat taatatggaa aaagctaaga aattaggtct
     3961 atttagtatg atattattag ggattaatag cataataggt tcaggtatat tcttactacc
     4021 aggtaaagtt tataatctag caggtcaaaa cagtatgttt atatacattt ttgctacact
     4081 cttagttcta tcaatacttt tatgttttgc agaagttgga agcatgtttg ataagaatgg
     4141 aggagcatat ctatactcca aaaaagcttt tggagatttt ataggatttg aagttggtac
     4201 aatgtcttgg gttattagaa ttatatcatg gtctactcta gcagtaggat ttgcaacagc
     4261 tttaggttca ttttggccag aatctgccac tgaatacaaa ggttatatag ctgcaatact
     4321 cgtaacactg ctttcaataa atagcttatt tggaattaaa agcacaaaga taatgaataa
     4381 tgtaataact atagctaaat tagtaccatt aatagttttt ataatagttg gaatattctt
     4441 tataaagttt gtaaatattg ttccttcagg aaatgtagtt aactctagta tgggtccagc
     4501 cattatatta gtattttacg catttaccgg ctttgaatca tttattgtgg caagtggaga
     4561 aatggaaaat cctaaaaaaa atcttccaat cgcattaata accacaatat ttatatgtgc
     4621 aataatttat atattaattc aaattgtctg tatgggtata cttggagata gactatttga
     4681 aaacagtatt ccaattgcag atgcttcaag tgtattttta ggaaattatg gtaaagtttt
     4741 catatctgta gcaacattaa tatctatatt tggtataaat ataggttcat caatagtaac
     4801 tcctaaatgt ggttcttctc tagcagaaga aggttctctt cctgcattta taggaaaaac
     4861 aaataaatat ggtgctccat atgtagcaat aataatatct ttaatttgtt gtataccact
     4921 tgtgctaact ggaagttttg aacaacttgc agtaatgagt gtaattgcga gatttgctca
     4981 gtacatacca acttgtttat cagtaatagt tttaagaaaa agaacagatg ttaaggcctc
     5041 ttttaagatt ccctttggtc ctgttatacc aatggtagct attttaggta gcttatggtt
     5101 gttacaacaa gcttgggcag aagatatttc aaaacctata actcaaaata gagttttaat
     5161 aggattaggg gcaatgttgt taatagctcc tctatatata tttatgaaaa aaaataaaga
     5221 aatcgagcat aaaaataaat cagaagattc taaattatat atttcgagag aaaaaattca
     5281 ataatatttt acaaactatt taaaaattat ttttctaata ctatagaaat aattagaaat
     5341 ggagatgttg catatctaaa agtagttgat aacacggata ttggtacttt tatagatatg
     5401 ggacttacaa aagacatact agttcctttt aaagctaaga cttatccatt gtttagagat
     5461 gaaaaatatt tattctatat atacttggat aaaagcggaa gaatagctgc tactacagac
     5521 atagattcat atttagaaac agaccatact tacaatgtag gagatgttgt aaatggagtt
     5581 gtatatggat tccaaaccaa caactctgct atgatatgtg ttgacaataa atatgctggt
     5641 gtaatccttc ataatgaata ctttacagaa ttaaaagctg gggatgttct tgaaaattta
     5701 catgttataa aaatatacga tgatggtaaa ttaggatttt ctcctagagg aaacagaaaa
     5761 gatgaacttg ataccttaga aaataagatt ttaagctatt tagaaggttc agatggatat
     5821 atgagattca atgataaatc tgatcctaaa gatatttcta tcttatttaa ttcaagtaag
     5881 aaaaatttta aacgtgctct tggagtactt atgaagaaag acttaattta tcaagatgaa
     5941 gatggaactt atctaaagta aattatataa cacaaaaatc gaagtaaatt atgaaagata
     6001 ttttctattt catatttact tcgatttttt atttaaatta ctacttatat ttattgtgca
     6061 tttactacct ctattatgtc taattcacaa atctttttaa ttggttttct tactgcaagc
     6121 aaagttatta ttatcatagt tactacaatg ataaacagta aatcaaaagg tatttgccag
     6181 tctatatgga attttaatgt tactaaggat acaaatatat atctatgtaa tattaatcca
     6241 agtacactcc ccaataaaca gccacttaca gcatatgtac ttgattctac tattaccatt
     6301 tttcttaatt gcttattgga catgcctatt gcacgcataa taccatagta atttattcta
     6361 cttgtaacgc ttatattcat actgtttatg atattaaaca tacttataat cgcaattata
     6421 aatacaaacc catatacaaa aactgccata gtgtaaaatg aatttttagc ctctaagtta
     6481 ccttgtctct tatctcgaac ctctaaatta tcatctagaa catttcttat attttggatt
     6541 aaatcttcag gagcatcttc atcaacttga gtatcaatta ttatatagtc ttttatatct
     6601 gttatactag taaaagtatt ttcagatgtt ataatatttc caatatattt gtctttaaca
     6661 tcaaatgaaa ttgaagaaag tatacctgct acctctatct ctttcttaga atttccattt
     6721 ttaatatata tcttatctcc aatattaaac ccatgacctt cttctaccaa tccgatattt
     6781 tctgactcta atttatcttc attgatttcc ccttttacta gatacttttt ggcccagtca
     6841 aattgatttt tttcataaga aattagctga gatgttgcct ccttattatt gtatgtagcc
     6901 tctacatccg tcatcattct actatatact ttttttattc ctttgatatt acttatttca
     6961 ttaatatcgt ctttagtaag aacagactta aagtcagcgt caacaataga tatatgagca
     7021 gcttctggtt ttataggttt aagtgcctga tacataaagt ctataaatac actaaaacct
     7081 aaaaacaata caatactaat agcaaatgaa gaagtcataa gtataaaaga tttttttctt
     7141 gaaaaggcat gatttattcc catagaaaca tcaattttag aacttcctgc gttagcaatt
     7201 ttacttgctt ttccactagt taaaatttct ttgaacatta gattaccacg tatagcactt
     7261 agtggagaca ccccagaagc tttttttgct ggaacaatag ctgataatat tactgttaaa
     7321 aatcctacta ttattccaaa cacaatacca ataaagctaa cctttaaaat tggcatcgaa
     7381 ccaaataact ctgtattcac atatttgaga aatatagagg atataatggt tacaatacat
     7441 cctaataaca atcctagtgg aatagccttt acacttagaa ttaaactttc taaaacaaca
     7501 aattttttga cttggagttt tgatgctccc aagcaacgta atagtccaaa aaactttatt
     7561 ctctctatta cacccatatt aaagctatta tatatcatga taatacttgc tattaacaca
     7621 agtataaaaa gtcctcctgc tgttaagtaa agtggtttag aataatcaga gtcaccttga
     7681 cctataatag aaagtaattt ttcattttta ccgatttgtt tatcacttaa attgaaggta
     7741 ttcttaatat cagaagtagc ttttctaata ttaaccttgt ctttaaatgt aatataataa
     7801 taatcatatg tttctgattt tttgatagct tgtgtaccta atattgaaag cattaatcca
     7861 tgcttatctg aggctcttaa gcttgataat gatgaatatt cacctactat cttataattt
     7921 ttatttctac catctgctaa ttttattttg ataaaatctc ctacttttag attaaagctt
     7981 ttaactgcat ccacatctat taaagtctca ttctccacaa caggataacg accttttatt
     8041 atttctagac ctaattgttt tgctaaatct tcatctaaac cttgtatcaa aatctccttt
     8101 gatttaaact ctccattatc aatgacttgt cctctaccat agtgagctat atctactcta
     8161 ctacttattt ctgatatagc ttcttcatta agatttttaa gtactatgtg ccaatttcca
     8221 tcatctttta taaattgtac tttttgacat tgtatagcca tgtctgctag tccaaaaata
     8281 gcagtaacta aacatactgc aatgacaata cataaaattg tagttctatt ttttttctta
     8341 tgtacctttg catattgtgg tactagttct aaatagcttc tcattctcta ttcaccccta
     8401 ggtctttaag cattccatca gaaacctgta gtatcctatc tgctgtagaa gctatatttg
     8461 tattatgagt tatcataata atagtttggt tatatttttc tgctgtcact tttaaaagtg
     8521 aaattacatc actgctattt ttactgtcaa gatttcctgt tggctcatct gccaatataa
     8581 ttgatggctt tgtaatcaat gctcttccaa ttgcaaccct ttgttgctga ccaccagata
     8641 attgatttgg aagatgactt tttctatctt taagacctaa aattgtcaat acttcatcta
     8701 gataaatagt gtctggtttt ttgtaatcta gtagtaaagg aaatattata ttttgttcca
     8761 cagttaattc gggtataaga ttatatgatt gaaagataaa acctatatta cgacgtcgaa
     8821 aaatagtctg tttttcttct ttcattgaac atatttcttt accatcaaca aatatttttc
     8881 ctgaggttgg agtatcaaga cctcctaaaa gatttaataa tgtactctta cctgagccag
     8941 attctccaac tacagtaaca aactctccct ttgaaactgt aaatgataca tcttttaatg
     9001 cctctacttt tgtatatcca tttccatatg ttttacataa attattaacc acaagaatat
     9061 ccatttgctc tatctccttt ctgatgatta atataagaat aattcataca ccttactgta
     9121 agatgtatcc tatcttacat attagtaagc tttaaaaaac ttagagtaaa tgtacttcct
     9181 tgtaaaaaat tactttctac agttatggtt ccattgtgct gttctatgat agatttaact
     9241 agtggcaacc ctaatccaag gccttgatta ctttttgaaa acttactcct ataaaatctt
     9301 ttaaatatat gatgtatatc ttcaatatga attccatttc cggtatcact cactgaaata
     9361 atagttgtta taggtgtttc aacccattct atcattattt tatcgttctc ttttgtatta
     9421 tctaatgcat tttttataag gttgcttaaa gcttctgata tccattcata atcgcaaaac
     9481 aagtttgtat tttctagacc tcttatagag atactctttc cttctttttc tgctctagtt
     9541 tcaaaactat ataaaatttt agtaatcaac ttttttacgt taacactagc tttgttaaga
     9601 attattgtct ttgaatctat ctttgtaatc tttaacaagt tttgtatcaa tgattctata
     9661 cgctctaatt cattttgact cttctgcaca aaattctcaa caatttcact attatgactc
     9721 tcttcctgca atatttgatt atacatcatc aatgctgtaa gtggagtttt tagttgatgt
     9781 gatatatctg aaattgtatt tttaagaaat tctttattct gcttttcttt caatatatgt
     9841 gtgtttagag atgttgacat agcatctatt gaaccaaata actttgataa actaccttct
     9901 tcataagtat ttaaccgtac atttatattt ccattcataa atgaatcaat tttataacta
     9961 gcttcttcta tcttgttctg ttgcctaaaa aaatacacat acaatataaa aataatcata
    10021 gtaaagaaca caaataaata caaaaacata gtttttatat atttaccttg aaacaatttc
    10081 acacttggca taaaactatc atctgtacca aagtcatatc tagctgtatt taagatttct
    10141 tttcctttta aagtatattt atcttcatta gtagtaaata ctgctggtat ttttgattta
    10201 tcaacaccca tactatttaa gtatccagct atattataat catgttctaa cagtgcactt
    10261 ttataatcat tagttatatt tataactact atttgaccta ctactataaa catcaataaa
    10321 acggatataa tcaccaaaaa aaatattttt atgtctttat tagaaaatac cttcatatta
    10381 acaccctcac tttataacat tccatttgta acccattctt ctaactgtta atagaatttt
    10441 tggattttca ggattatctt caatcttatt tcttaacctt cttacatata ctgacagagt
    10501 attatcatct acaaaactac catttccatc ccataactta tccaatatat tttttcttgt
    10561 aagtacaata tttttatttt tcataagtaa gcataataat ttatattctg ctgtagtaag
    10621 ctcaagctca atttcatttt taaaaacacg attttcaagt aatttaacag taatattatt
    10681 tgattttagt tcagttacat tttcacttgt aaaattataa cgtctaagta aagcttttat
    10741 tcttgaaatt aactcattta atttaaaagg ttttgttatg taatcatctc cacccatatc
    10801 aagtcccatc actacattta cttcttcatc agaagcagtt aaaaatatga ttggtacatt
    10861 agaagcttct cttacccttt tacaaatatc aaaaccatca ccatcaggta aggatacatc
    10921 caaaagcagt aaatcataat ttttttcttt ataaatttgc aatgcttctt ctactgttct
    10981 tgctacatca acactaaatc cattcttttg tatagaatat tctaatccat atatcaaact
    11041 taaatcatct tcaaccaaca atatactact catctcaatc acttccattt ttttattttt
    11101 tactttatat atattatata cctaacttat tatattttta ctcttttaaa aatacaatac
    11161 cttgaaatca atgatttaaa tattttaaaa ttatttttat atgattttat atagttaatt
    11221 taatactttg aaatcttaat aataaaaaaa gcttaaaata cactaagtat tctaagcttt
    11281 attcaatcac attttatata tttatattat ttattttttt aaaatactat tttcaatatt
    11341 gcctctatta aacatttcat tatcattatc taaagagata tcacttatat ttctaacagt
    11401 tgttgaatag ttaccactaa gttctatctc actgaaatgc atatacacta tcttttgtat
    11461 tacaaatccc attgatgcaa gtaaaatagc aaatattata tactgactaa agttactcat
    11521 ataataattt ataatggtat attcatttcc tgtgactgtt aaatgttttg tagatagcat
    11581 atatatattc agtacaattt ataaatacat atataccata aatagccaac actacagata
    11641 aacaatacat tgtgattgaa atctttgata tttttttaaa cttactatct ttacaacact
    11701 taatatttgt tatttatcat aaacaaggtt attgtattat caataatttt taggttacac
    11761 ttattattag tcttgtgtta aaacgacagt agacttaaga gtagagtttt attaagccaa
    11821 tatttatatt tgctatacat tgtaccccta ttacaccata catataactt ggataactta
    11881 ttttattttt atttctaaat tatttaaaat caatatctac accattatcg ataattgcaa
    11941 ttaatttcat ataaaacctc tttaatttat aggctgttca ctataaagtc tttatttctt
    12001 ccataaaatt ttcattttga attttattca atgtttttag tgtagttatc atgattatag
    12061 atactaaaat aaatactatt aggataatag cccctataaa tttccaattt attaaattga
    12121 tactttcaaa aggttttatt attatacttc ttacaattaa aataggtatt atagatatac
    12181 aaaagcttac tataatatat atataacttt ccaatttaac aattttattt atttcatgtt
    12241 ttgatattcc tattcctcta aatagtgcaa attccctact tctgctatta atactagtaa
    12301 ctatagtatt gcaacagtta aataaagata atataactat aattccagtt actaatacca
    12361 taattagtgt tttttgatta tcaatttttt catattcagc tgtttcagct ttgtatggaa
    12421 ttaaaattcc tttatttgtt ttttctgtta ttttgtttaa ctcactttca acatatttat
    12481 cattggctag tttactcgtc catatgtcaa atctttcata agatgatatt cctgtaaact
    12541 tattaaattg atttgttgat attactccgc caaattcagc tcccacttgt gaggttactg
    12601 gtaatgtagt tataattcca catactataa attcttgaga tattgttttg gtaaaattat
    12661 ttgtttttga atctataata tcaaagtata cttttattct atctcctttt tttatattaa
    12721 gcgaatcact ggatttcttt gttatataca gatatggttg tttactaaat ttatctatat
    12781 tttcctttcc atttatcaag aaatcctcta gtatatctgt atcttctatt cctaaaaatt
    12841 caaaagaatt attatatacc ttaattccat cttttacttc tgatctagct tcaatattat
    12901 ctttattttt tttccaataa tcagagttct tatttatact tttatcatca atttttatat
    12961 taaaccactt atgcctatat gagtttactt ttgttacacc atcaattgcc tttatctctt
    13021 gtagtacatt tttatcataa cctttattat ttgaacgtat agtacttata tcaatattat
    13081 gtaataaata atctccttgt atccaatatt ttaatacacc atcacttaaa aagttactag
    13141 tagactttgt gtatattgtt gccattaaga aaaatataat taccattgat gctatagata
    13201 aatttgtacg tttcttattt ctttgtatat tttttgatgc tatgttacca tagtctttga
    13261 aaagttttat cataaattta tttataaagg aattttgttt tatatccact ttttcattat
    13321 ttcttcttat acaaatcatt ggatcagttt taactgataa cataagaggt tttgaaactg
    13381 atattattat agttcctaaa cttaataata tagaaattat gtatgtgttt atatagttct
    13441 ggttttttat agaatttata tagttgacat tgtatattac tcctataaca tactcccttg
    13501 ataaactagc tattatccca cctaaaatta gacctataga aatacttata atagagtata
    13561 tagatacttc taaaatcatt attttaaaaa tatcatttgg attaaaccct aaagccctaa
    13621 atatcccaaa atcctttatt ctatttgata ctaatatata aaaaatatta taaattaata
    13681 atatagttgc tagtgctagt actatattaa ctattatata aggtattttt aaattcatac
    13741 tatcagatat agctattaat aattcattat taaaataaat gttattctca ttcaaatttc
    13801 catttttaat aagtttttgt gattgtctct gtatattttt ttccttttta aaagtaaaca
    13861 taatttgatc atatttattt ttagtaggaa tattcttgat agcacaatcg ttacttataa
    13921 ggccaattga tgttccttga gcttttaaaa taggattact atttaagata ccagttattt
    13981 taaattcttt ttccccagta tataaatctt cttgatctat cccttgtctt ctataatcta
    14041 atgttatcct ttttcctata gggtttttta tctttttttg tttaatatac catgaatcta
    14101 tagcgatttc attttcagct actggtaatt tacctttttc tagtgtgtaa atatcattta
    14161 gttcttcagc aactttatcc tgagatagaa tttgtagtgt ttgaccttta ccaatatcac
    14221 taattcctaa aagcattgat tttccaactt tatctatact tgtgttattt tctatatatt
    14281 ttatttcttc gtcttttgga ttgatatatt gtgcatgttt taatgtaaat tcatttttag
    14341 cttgatttat cattaagttt gtcgcatctt cacttattat attcataatt aaaaacaacg
    14401 ctgttgaaat tacaatactt acaattatta ataatgtatt tttcttattt cccattatat
    14461 atttttttac aatataatta agtttcataa atctacctac tctcttataa atccatcttc
    14521 tatttctata actctatcag catattttgt tatatctata ttatgtgtta tcattattat
    14581 tgtctgatta tatttttttt gagattcttt taataaactt aatacatctg actctgtctt
    14641 tgtatctaaa tttccagtag gttcatcagc aaatacaatt gatggtttat ttacaagagc
    14701 ccttgctatt gctactcttt gttgttgccc acctgataat tgatttggca aatacattct
    14761 tctatctttt attcctagta actccatcaa ttcattaata taagcttcat ctttattttt
    14821 tatatttata gttggtagtt ttatattttc ttcaacagtt aaaactggaa tcaaattata
    14881 tgattgaaat attaatccca acttttcttt acgtaatgca gatcttttct tttcatcaag
    14941 agatgatata tttatattat caataatcac atcaccattt gttggagttt caagtcctgc
    15001 cattatgtgt agtaaagtac ttttcccact tccactttta cctactatca caacaaattc
    15061 tccactattt atttttagat ttatttgact taacgctttc acctctgttt ccgatttacc
    15121 atatatttta tttaggtttt ttatctctaa aatactcata atttactcct tgtcttacat
    15181 gttatttaca cttataaatt cgatttttgc tatggatttt gcaatctcta tctatactta
    15241 ttgatatgta gcaacagaaa ctatttttat aattttcaaa aaattcttcc gcctattcac
    15301 tccatatagt gcctttagtt atcataccat atcttataat tgaattttat ttcttatatc
    15361 tcttttacca acctttttat ttaggaaaag ttcttcacca tgaaattgta cagtatatac
    15421 ctatttcttt gattatataa ttaagctttt tatttagtaa cctactttct acatcctaac
    15481 ttatatttcc tgtttcctca ttttcatatt tataacaata gttacaatct aaattactac
    15541 ttttagttac ccagacttta ctttacatgc tttgcctcta aactgctgat gttaatatct
    15601 tcttaatttt ttcacaccta tcttcaaata taaaatcttt atctaaaaga ttattgtatt
    15661 cagctagaca taaccaacaa aatgatttca ttaaatattc tttacattca ttattacata
    15721 actttaagtt gaaaaactca ttatatccaa aattcgttga tacccatatt attaatataa
    15781 cttacaatgt ctttttgaat atctaaaaaa atacttttat aacttatttt atatatcata
    15841 cactatatta ttgctttcat aatctataaa ggtttcatat gatacaaact tctaagatgg
    15901 gatttttggt ctttaataac gattataata atatttattt atatttctga tttaaacatt
    15961 attttacttg aaatgtttat taaataaatg aattaaaact aaactttcat tatattttta
    16021 atttattcaa ttaaatttta gcatagttat ataaaatagt atatataatt atacaagata
    16081 atagtaaata taactatctt ttatatattt tttctaaatt taaactttag tataaatata
    16141 taagaaatat cataatattt ttaaaaactc aaataaagct aaacaagtat tatattcttt
    16201 attttagaaa aataaaaact gtaagcaaat ttgttttcac acaagtttac ttacagcctt
    16261 cacctcaatt ttactttaat ataatccatc tattctaaaa ctgattcaat atattcgaca
    16321 gttacatcca ttcttttagc tacctcatct attgaaagac cactatctaa aaaacgtcta
    16381 cacacagatg acatagtttc tccaacctca ataatatgcc catctaaatc ataaaatcta
    16441 attgctcttt gaccccacct atgctctata gctagatgaa cataatctat atctttcatt
    16501 gtactcaatc tttcaacaaa agtatcaaaa ttatcttcct caaaatataa ctcagcatca
    16561 tttccattga acttaacttc actgtcactc ttattaataa attctaacca aagctttttt
    16621 tcttgtaatg atatattacc ttctaataca acattttctc caaaatcaca gattaccttt
    16681 aaccccaaaa tatcataata aaactttttt gatttctcaa tatcttcaac tactattaaa
    16741 acatttaaaa acttcatatt acctccttaa tatacacata ctttatttat aatatataat
    16801 tagaattaaa ctataaaggt ttcaataagg tctagtataa agaaaaaaat tataagtctt
    16861 attgaaatag ttaagttaat tttatcatat aatataaatt ttaatcttgt aaaaaacaga
    16921 catgttcata cttttaggtt taaatctata tgtattctta ttaattttgc taaaactgtt
    16981 atttttgtag actattttag attactgaaa tatctatgtt tttttaattt caagggaata
    17041 ttaatataca ctaataatat taatatcacc tttaaatatt acaagtatat gcattttata
    17101 tgattaaaga gattattcaa atattctaat taataaaaat atagttttta gttcttctaa
    17161 tttagttttt ataatctttc taattattga tattttatta
//
LOCUS       DAEORM030000070        17095 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.072, whole genome shotgun sequence.
ACCESSION   DAEORM030000070 DAEORM030000000
VERSION     DAEORM030000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 17095)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17095)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 17095)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17095
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.072"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            complement(186..710)
                     /locus_tag="KRH23_003226"
     CDS             complement(186..710)
                     /locus_tag="KRH23_003226"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HHS5226500.1"
                     /translation="MENKNPIVTIEMENGKEIKIELYPNIAPNTVKNFVSLVNEGYYN
                     GIIFHRVIPGFMIQGGCPNGTGMGGPGHSIKGEFSGNGFTNNLKHERGVISMARTMAP
                     NSAGSQFFIMHKNSPHLDGQYAGFGRVIEGMDTVDEIASVRTDSADKPQTPQIMKSVT
                     VETFGIDYSDVEKN"
     gene            complement(775..1527)
                     /locus_tag="KRH23_003227"
     CDS             complement(775..1527)
                     /locus_tag="KRH23_003227"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052689 - carboxylic ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HHS5226501.1"
                     /translation="MKLGLCLEGGGAKGAYQAGVVKALYDGGINKFYSISGTSIGAIN
                     GYYLYTGNVDNLEKMWTNIKDIQNGNVKIVNNTVDNSPAIDNLRELDDSNIEEMNFYV
                     NYVEVDNKVVSEKIVDVSKMPRNEAIISISYSGLLPSNPNATLGFKEQFVKDVQEGIY
                     DGFKLDGGLIRSALIEPLIGDNVDKIILISTKYNYELPEDIKKVYDEDKIIVVRPNTQ
                     FAPKDTLNFDDEFCKTIYQEGYEIGKNILDRL"
     gene            complement(1558..2856)
                     /locus_tag="KRH23_003228"
     CDS             complement(1558..2856)
                     /locus_tag="KRH23_003228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004177 - aminopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M18 family aminopeptidase"
                     /protein_id="HHS5226502.1"
                     /translation="MDSINFAKNLIDFIYDSPSSFHAVESTKEILDKNGFEELVLNQR
                     WNLRVGGKYYVTKNLSAIVAFVVNSEGIERDGFRIIGSHSDSPTFSIKPNAEIEAEKS
                     YLKLNTECYGGAILSTWLDRPLGIAGRVVLKGDSILKPNERLIDFKKPICIIPNLAIH
                     LNRSINDGHSYNKQKDMLPLVGMLNDTLEKDNFLIKQIASNLDVNMEDIIDFDLFLYE
                     FEKGSLIGANDEFISIGRQDNLAMVHASLNALVNTKGQHGVNVMAVFDNEEVGSSTKQ
                     GADSNMLLNILERICISMGKDREGFFESIYSSFMISSDLAHAIHPNIPEKHDPTNKPI
                     MGKGPVIKINASQAYTSDGYSIAIYKNICREANVEYQEFVNRSDERGGSTIGPISSTH
                     IDIPSVDVGSPILAMHSIRELGNVEDHYSIYKTFSKFFEI"
     gene            complement(2873..5137)
                     /locus_tag="KRH23_003229"
     CDS             complement(2873..5137)
                     /locus_tag="KRH23_003229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3553 domain-containing protein"
                     /protein_id="HHS5226503.1"
                     /translation="MNLDTLNPAQREAVEKTEGPVLILAGAGSGKTKVLTTRIAYLIE
                     DKGVQAPNILAITFTNKAANEMRERVEQNIGPETKDMWISTFHSCCVRILRKDINKIG
                     YNRSFVIYDSADQVTLVKDCLKELNLSDKVFEPKAVISAISGAKDKLYTPKQFKDINM
                     ADNRMVKIADIYALYQDRLKRNSALDFDDLILKTVELFKANDEVLAYYRSRFRYIMVD
                     EYQDTSKAQYELIKLLAREHQNICVVGDDDQSIYGWRGADIRNILEFEKDYDNVHVVK
                     LEQNYRSTQVILDAANKVISNNIERKRKKLWSEKKEGELIKIQLTGSEIEEADFIADS
                     IAQIARKENRPYKDFAVLYRANAQARPVEDALNRSQIPYNIYGGTKFYERKEIKDLLA
                     YLRVIQNPQDDISIKRIINVPRRGIGLRTIEKIEDRANLKQESIYSVLIDIETNSDIS
                     TKARASISGFVDIIGTLRTIKEVYPVSKLIEKVLDTTGYMDELVEIRNKNEKDLTGKG
                     EEAQDRIDNLREFISIALEFESSNDDTYENKDLETFLTSIALTSESNDEEDNDRVSLM
                     TIHTSKGLEFPVVFLTGMEEGLFPISRAIKSMSDSQIEEERRLCYVGITRAKEELYMS
                     LTEKRTLYGKTNVAIASRFMEELPEECIERLYKVKKELSYSKASYNMLDKYTKKYMST
                     ISKSKVADKVNATIKDSNKETNPDDIKLGSKVHHPKFGVGTVVSIIGTDVTIAFDQQG
                     IKKINKEYTTLNIL"
     gene            complement(5392..6210)
                     /locus_tag="KRH23_003230"
     CDS             complement(5392..6210)
                     /locus_tag="KRH23_003230"
                     /EC_number="3.6.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HHS5226504.1"
                     /translation="MFKINNLTYQYEKNTNALLNINMDFSKGNVIGIIGSNGSGKSTL
                     FMNLMGILKPTSGEILFKEEKLKYDKRSLYNLRKNVGIVFQDPEKQIFYSKVYDDIAF
                     AMRNIGMDEKTIKERINKALVAVNGIDFIDRPVHFLSYGQKKRVAIASVIAMENEIVL
                     LDEPTAGLDPVSTRSIVDIIKGLNKNNIKIVISSHDMNLMYEICDYIYVLDKGILIDE
                     GKAENVFINENNIIQAGLESPWLVKVHRNMNLPLFKKEEDLYKYWKERELNTNK"
     gene            complement(6203..6901)
                     /gene="cbiQ"
                     /locus_tag="KRH23_003231"
     CDS             complement(6203..6901)
                     /gene="cbiQ"
                     /locus_tag="KRH23_003231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0032778 - P-type cobalt transporter
                     activity [Evidence IEA];
                     GO_process: GO:0006824 - cobalt ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ECF transporter T component CbiQ"
                     /protein_id="HHS5226505.1"
                     /translation="MLIIDKYAYTNRLSKVNPNKKVAIGVIFLIASMVIQNIFILSGI
                     MILMSILVVCVAGIDLKNYLKLLRIPMYFLFLSIGITLVNISFNKADLLYSFEFFSFN
                     VGISKASIDMSIHVLFRAMSCLTCVYFCILTTPFNQLIFFFKKLHLPDTFVELSMLIY
                     RFIFIFLEEFSEIYKSQELRFGYINLKTSYKSLGILGSMLYKRLMTRYDDMCISLDIK
                     LYDGKFHIVGDNDV"
     gene            complement(6904..7188)
                     /locus_tag="KRH23_003232"
     CDS             complement(6904..7188)
                     /locus_tag="KRH23_003232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015087 - cobalt ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006824 - cobalt ion transport [Evidence
                     IEA];
                     GO_process: GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     substrate-binding protein"
                     /protein_id="HHS5226506.1"
                     /translation="MSAKTKTKTNILLLLLVVALIIFPLLVNSGAEYGGADGQAESEI
                     TKINPNYKPWFSSPYEPPSGEIESLLFSAQAALGAGVIGYILGLQKGKRS"
     gene            complement(7178..7930)
                     /locus_tag="KRH23_003233"
     CDS             complement(7178..7930)
                     /locus_tag="KRH23_003233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_process: GO:0000041 - transition metal ion transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter permease"
                     /protein_id="HHS5226507.1"
                     /translation="MKQNIKLGVIAALMLIILTPVTSNAMHIMEGYLPVKWSIAWGVI
                     FIPFFLFGLKSIGKIVKQDPKKKVLLALCGAFVFVLSALKIPSVTGSCSHPTGVGLGA
                     IMFGPSVMFVLGTIVLIFQALLLAHGGITTLGANAFSMAIIGPIVSFLIFKALKKKDG
                     NNAMPVFLAAAIGDLATYTITSIQLALAFPDPSGGVMASAIKFLGIFFMTQIPIAIAE
                     GILTVIVYNLITENGEKSILENNDKGVKANEC"
     regulatory      complement(8113..8304)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
     gene            complement(8436..10208)
                     /locus_tag="KRH23_003234"
     CDS             complement(8436..10208)
                     /locus_tag="KRH23_003234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitric oxide reductase activation-like protein"
                     /protein_id="HHS5226508.1"
                     /translation="MKWIYDDYEFENRANNLSWTIAGDYNESIDISEKDYSSKEIGLY
                     FAIIAGARRKYVDWDIVKKYLTNRIRKGYNKDIILGLIQVILNTIVEEKVIKDRPGIE
                     DIRRNAYKDIVSRFTKIHNDNIMDKIKYTFVLYSMDKHPALDSMTRRIVNDIRNIDTN
                     QDIMEILKALDVIYLTYFEYILNGEENSLIDENNVESVEVNFDTFADFMYEELYSDEE
                     ENIIESDIDSISSSMLVEGVGDFDDSKCNNSADRVIYVDEDTANKIYSKIEHYYGKTY
                     LSKGEIKKIETQNCRNVHEGCRIHFTDGVLRSECNNVFQLKYVTRQKENNLGKFREHA
                     RMYRQQIKRLKESLSRILIEENAKSRVYSDCGTILANRAWRVGRSNNNKIFYKDIENE
                     KGKYVIDILLDASGSQSRNQGNVAIQAYIIANALTEVGIPNRVMGFSSFLDYTILKRF
                     KDYDDSIKNSENIFEYFCAGNNRDGLAIKSICSGLINRDEENKILIVLSDGRPNDVKI
                     GKSSERTLRGEKAYRGIVGLRDTANEVRKARKQNILVLGVFTGKESELEAERLIYGND
                     FIYSRDITRFSDVVSMYLKKIIRN"
     gene            complement(10222..11151)
                     /locus_tag="KRH23_003235"
     CDS             complement(10222..11151)
                     /locus_tag="KRH23_003235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HHS5226509.1"
                     /translation="MDIIDNLRVQGVDEKLIEDVLYFRNYYGLEKDLEYRVTKSKTYF
                     YGKDILSMCIAAILEEENILLSGPKATGKNLLADNLGEIFNRPQWNTSFHINTDSSTL
                     IGTDTFIDNEVKLRRGSVYECAINGGFGVFDEINMAKNDAIVVVHSALDYRRIIDVPG
                     YERVNLHPATRFIGTMNYEYAGTKELNEALVSRFMVIDIPPIEEDKLMMILKNEFSDA
                     DEEKLIHFAGIFLDLQLKSQNGEISSKAIDLRGLMASLKTIRRGLKPTLAINMGLTGK
                     TFDVYEKEMVGDVIKTRIPNKWESIDVFPISHI"
     gene            11380..11568
                     /locus_tag="KRH23_003236"
     CDS             11380..11568
                     /locus_tag="KRH23_003236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHS5226510.1"
                     /translation="MEYMSCPEVAKKWGISERRVQKLCEESRIPGVSKLGYMWLIPKN
                     AEKPVDGRTKRRKEVQYE"
     gene            11561..12262
                     /locus_tag="KRH23_003237"
     CDS             11561..12262
                     /locus_tag="KRH23_003237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HHS5226511.1"
                     /translation="MNSVLIIDDDKELCALMKKCVEQENLSAITAHCGAEGLHLVDKN
                     RHTLSLVILDIMMPDIDGFQVLKKIRETSNIPVIMLTAKNDEDDKVSGLRLGADDYLT
                     KPFSINELMARVNSLIRRYTMLNPAFITDTDCIIINGMIIDKTNRIVSVNNIPVQLTS
                     KEFDLLAFLASNKGRVFTKKQIYTQVWEEEYAFDDSNIMSFISKLRKKIEPDPNHPFY
                     ILTVRGVGYRFNKEA"
     gene            12264..13187
                     /locus_tag="KRH23_003238"
     CDS             12264..13187
                     /locus_tag="KRH23_003238"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HHS5226512.1"
                     /translation="MNTSVYLLLILALSLIIIAYLVSVLLRVRIQLTLIKDALEDIKN
                     GNLNRRILTDENDITKQICYDINEIAINSQFQLIQQKQSEQAYKQLMTSLSHDVKTPL
                     ASLVGYLEAVESKIVVGEEKDEYIHVASNKAHYLKNFVENLFEWVKLDSKEQVFHFDI
                     FDLNELSRNIISDWIPVLESSHFEYEFDIPEIEYFLRIDANAYTRIINNLLQNIITHS
                     SGNKMTLRIFENKEQAQIIITDNGKGISSDNLPHIFERLYQCDHSRASKGNGLGLAIA
                     KELINAHKGNITANSTPGMGTEFTILLPKAL"
     gene            13344..14267
                     /locus_tag="KRH23_003239"
     CDS             13344..14267
                     /locus_tag="KRH23_003239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019639192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHS5226513.1"
                     /translation="MNDFVIETKQLTKIYGNQTVVDKVNLHVKKGRIYGLLGRNGAGK
                     TTIMKMILGLTSITYGEVDVFGENIKGREKQVYPRIGAIIETPGFYPNLTGTENLEIF
                     AKLRGTAAPNSVKRALEIVGLPYKNKKLFSKYSLGMKQRLGIANAILHDPELLVLDEP
                     TNGLDPIGIAEMRKFIRDLSVEHGKTILISSHILSEISLLADDIGIIDHGVLLEESSM
                     SELEKKNSKYILLQVSDIPKTSLILERQFNTKDYSVQDDYTLHLYNTNLDMGEINKAL
                     VMQNVIVISSQLCNDTLEDYFKKITGGEGIA"
     gene            14260..14997
                     /locus_tag="KRH23_003240"
     CDS             14260..14997
                     /locus_tag="KRH23_003240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHS5226514.1"
                     /translation="MLKLIQTEFLKLRRRKLIWLMLLSALIMPFFALLYFNYFGKTGV
                     EPTKFYKWSAFGYTLWIILPVVLGIFCTMLIHEENQYDMLKQLWIVPISKMGYFFSKF
                     FVVLIYSICFMLITAVASVLFSVLSGYVVFSWASILYLLKKCLEIGVITAFVMLPILA
                     IATSQKGYILPICITLVYAFSGFVIMTINMYLHPLSSMGVIIMRNKDIPGLIFSQEIN
                     VPLAFLCICIWSIVSVLFANIALGRRK"
     gene            15008..15781
                     /locus_tag="KRH23_003241"
     CDS             15008..15781
                     /locus_tag="KRH23_003241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHS5226515.1"
                     /translation="MWKLLWAECQKIRRSKIVWITVFASIMIAVIVFAGGQDVYNDPD
                     LHYGLKSVYDGSRYIDNAGWYMDAVQPWSTFFVLPAVIALLGSYIICREEEEDTIKSL
                     RLIPINETKLTIAKMIITFIFSILLYLLLFTITFLTESVLHFSDLSTKLVLSCMKEYF
                     LDGIGVFFAISPIIALVSRMKKGYWLALVFTEVYSIAGLFAGMSNVLQTFFPIAAIFN
                     ISGYYITTGEKIMGSIISLLLCACLSAFILKGLKHNEKN"
     gene            complement(16322..16930)
                     /locus_tag="KRH23_003242"
     CDS             complement(16322..16930)
                     /locus_tag="KRH23_003242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="HHS5226516.1"
                     /translation="MSVINSFILQYGLISVFVLIMIEYACFPLPSEVVLPLCGAIAAR
                     NHFGFLTILILSIIAGILGSIFCYTVGNWGGKSIINKIIEICPKAKKGIFASQDYFNK
                     YSSISVCVCRLIPLCRTYISFIAGIAGQNIITFVISSIVGITIWNTSLISIGYIFSES
                     WVRIMSHYNDYKFLVLIIPISIIFIGFVIKSFIHKKHHKIRL"
BASE COUNT         5505 a         2964 c         2155 g         6471 t
ORIGIN      
        1 atttttttaa taaaacttta ttttttagtt aaaatcatac aatatataga tttccacaat
       61 acaaataaat taaaaagtga aatgtatttg tctaaaaaca taataacatt tcactttatc
      121 ctcattttta agtaatatat atttttaatt tttatttata actaaatcta gtttttatat
      181 aaattttagt ttttttctac atctgagtaa tctattccaa aagtttctac agtaacagat
      241 ttcataattt gtggagtttg tggcttgtca gctgaatctg ttctaactga tgctatttca
      301 tcaactgtat ccataccttc tatcactcta ccaaagcctg catactgacc atctaagtgc
      361 ggtgagtttt tatgcattat gaaaaattga gaaccagctg aattaggtgc catagttcta
      421 gccattgata tgactcctct ttcatgtttt aaattgttag taaatccatt accactaaat
      481 tcacctttta ttgagtgacc tggaccaccc attcctgtac catttgggca tcctccttgt
      541 atcataaatc ctggtattac tctatgaaat attattccat tgtaatatcc ttcatttact
      601 aatgatacaa agtttttaac tgtatttgga gctatatttg gatataactc aattttgatt
      661 tcttttccat tttccatttc tatagttact ataggatttt tattttccat aatttattac
      721 cttccttttc attagttaaa ttacataatt acatttatta tattatactc taaattaaag
      781 tctatcaagt atattttttc ctatttcata tccttcttga taaatagttt tacaaaactc
      841 atcatcaaag ttaagcgtgt ctttaggagc aaattgagta ttaggtctaa ctactattat
      901 tttatcttca tcatatactt ttttaatatc ttctggcaac tcataattat attttgtgga
      961 tattaaaata attttatcca cattatcccc aattaatggt tcaattaatg cactcctaat
     1021 taaacctcca tctaatttga aaccatcata aattccttct tgcacatctt tcacaaattg
     1081 ttctttaaat ccaagagttg cgtttggatt tgatggtaac aacccactgt atgaaatgct
     1141 gataatggct tcattacgag gcatttttga tacgtcaaca atcttttctg atactacttt
     1201 attatcaact tcaacataat taacataaaa gttcatttct tctatattac tatcatctag
     1261 ttcccttagg ttgtctatag caggagaatt atccacagta ttatttacta tttttacatt
     1321 tccattctgg atatctttta tatttgtcca cattttctcc aagttatcaa cattccctgt
     1381 gtacaaataa tatccattta ttgctcctat tgatgtccct gaaatcgaat aaaatttatt
     1441 tattcctcca tcatacaagg ctttaactac tcctgcttga taagcccctt ttgctcctcc
     1501 accttctaaa cataatccta atttcatagt ctcatctcca aattgtttat cttatattta
     1561 tatttcaaaa aacttactaa atgttttata tatactatag tggtcctcaa cgtttcctaa
     1621 ttctcttata gagtgcattg ctaaaattgg acttcccaca tctacagatg gtatatctat
     1681 atgagtagaa gatattggac ctatggtact tcctcctctt tcatctgacc tattaacaaa
     1741 ttcttgatac tcaacattag cttctctaca tatattttta taaatagcta tagaatatcc
     1801 atcactagta tatgcctgac tagcatttat ctttataacc ggaccttttc ccattattgg
     1861 tttattagtt gggtcatgct tttctggaat gtttggatga atagcatgag ctaaatctga
     1921 tgatatcata aaagatgaat aaatagactc aaagaatccc tctctatcct tacccattga
     1981 tatacaaatt ctctccaata tatttaacaa catgtttgaa tctgcacctt gtttagtaga
     2041 gctaccaact tcttcattgt caaatacagc cattacattt acaccatgtt gacctttagt
     2101 attaacaaga gcattcaaac tagcatgtac cattgcaaga ttatcttgtc tcccaataga
     2161 tataaattca tcattagccc ctattaaact tcctttttca aattcatata aaaataaatc
     2221 aaaatctata atatcttcca tatttacatc taagttagat gctatttgct ttataagaaa
     2281 attatctttt tctaatgtat catttaacat cccaactaaa ggtaacatat ctttttgctt
     2341 attatatgaa tgaccatcat ttatacttct atttaaatgt attgctagat ttggtattat
     2401 acaaattggc tttttaaagt ctataagcct ttcatttggt tttaatatac tatcaccttt
     2461 taaaactact ctaccagcta tcccaagagg tctatccaac catgtactta atattgctcc
     2521 tccatagcat tctgtattta acttcaaata agatttttca gcttctattt ctgcatttgg
     2581 tttaatacta aatgtaggag aatctgaatg agagcctatt attctaaatc catctctttc
     2641 tataccttct gaatttacta caaaagctac tatagctgat aaattcttag taacataata
     2701 ctttccacca actcttagat tccatctttg attcaaaact aattcttcaa atccattttt
     2761 atctaagatt tccttagtac tctcgactgc atgaaaagac gacggactat catatatgaa
     2821 gtctattaag tttttagcaa agtttatact atccattcct catttacctc cattataaaa
     2881 tatttagtgt tgtatattct ttatttattt ttttaattcc ctgttggtca aaagctatag
     2941 taacatctgt accaattata gaaaccactg tcccaacccc aaatttagga tgatgtacct
     3001 tagaaccaag ttttatatca tctggattag tttctttatt agaatctttt attgtagcat
     3061 taactttatc tgcaacttta gatttgctta tagtactcat atacttttta gtatatttat
     3121 ctaacatatt ataacttgct ttagaatagc ttagttcttt ttttactttg tacaatcttt
     3181 ctatacattc ttctggcagt tcttccataa atcttgaagc tattgcaaca tttgttttac
     3241 catataatgt tctcttctct gtcaatgaca tatatagctc ttctttagct ctagttatac
     3301 caacataaca aagtcttctc tcttcttcta tttgtgaatc actcatagat tttatagctc
     3361 ttgatatagg aaataaccct tcttccatac ctgttaaaaa cacaacaggg aattctaaac
     3421 ctttggatgt atgaattgtc ataagcgaaa ccctatcatt gtcttcttca tcatttgatt
     3481 cagatgtaag tgctatactt gttaggaatg tctctaagtc tttattttca taagtatcat
     3541 cattactact ttcaaactcc aaagctatag aaataaattc tctcaaatta tcaattctgt
     3601 cttgagcttc ttcacctttg cctgttaaat ctttttcatt tttatttctt atctctacaa
     3661 gctcgtccat atatcctgta gtatccaaga ctttttctat aagtttgcta acaggataaa
     3721 cttcttttat agttctaaga gtccctataa tatcaacaaa tccacttata cttgcccttg
     3781 ccttagtaga tatatctgaa tttgtttcta tatcaattaa tactgagtat atactttcct
     3841 gttttaagtt agctctatct tcaatttttt ctatagttct aagccctata cctcttctag
     3901 gaacatttat aatccttttt atagatatat catcttgtgg attttgaata actcttaaat
     3961 acgccaacaa atcctttatt tcttttctct catagaattt tgtaccacca tatatattgt
     4021 atggaatttg acttctattt aaagcgtcct ctacaggtct tgcctgtgca tttgctctat
     4081 aaagtactgc aaaatcctta taaggtctat tttcttttct agctatttgt gcaattgaat
     4141 cagcaatgaa atcagcctct tctatttcgc taccagttaa ttgtatcttt ataagttctc
     4201 cttctttttt ttcactccaa agcttttttc tttttctttc tatattatta gatatgactt
     4261 tattagctgc atctaatatc acttgtgtag acctataatt ttgttctaac tttacaacat
     4321 gtacattgtc ataatctttc tcaaattcaa gtatgtttct tatatctgca cctctccatc
     4381 cataaatact ttggtcatca tctccaacaa cacaaatatt ttgatgttct cttgctaata
     4441 attttatcaa ttcatattga gctttacttg tatcttggta ctcatctacc attatgtatc
     4501 taaatctact tctgtaatat gctaacactt catcattagc cttgaaaagt tctacagttt
     4561 taagtattaa atcatcaaag tcaagtgcac tatttctttt taaacggtct tgatatagcg
     4621 cataaatatc tgcaatctta accattctat tatctgccat attgatatct ttaaactgct
     4681 ttggagtata aagtttgtct tttgctcctg aaattgcact tataactgct tttggttcaa
     4741 acactttatc acttaaattt aattctttta gacagtcttt aaccaatgta acttggtctg
     4801 ctgaatcata aattacaaaa cttctattgt aaccaatctt atttatatct tttcttagta
     4861 tacgaacaca gcaagaatgg aatgtactta tccacatatc cttagtttca ggacctatat
     4921 tttgttcaac tctctctctc atttcatttg cagctttgtt tgtaaatgtt atagccaata
     4981 tatttggtgc ttgtacacct ttatcttcta taagatatgc tattcttgtt gttaatacct
     5041 tagttttacc tgaaccagca ccagccagta taagtactgg accttcagtc ttttctactg
     5101 cttctctttg agcaggattt aatgtatcta aattcatatt tctcctcctg ttaacagcca
     5161 taaatatatt ttaatctaaa atatgaatta cttcaaatta taattatgta ttatattaat
     5221 agattatttc caatatatta caattaaata acatttttcc atataattta tttcattgtt
     5281 taataaaaaa aataacctta tgatttgggg aatcataagg cacctttaag gggtctaggt
     5341 taagggttat tatatataaa tctatttttt aaaaataggt ttagggctta attatttatt
     5401 tgtattaagt tctctttcct tccaatactt atacaaatct tcttctttct taaataaggg
     5461 taaattcata tttctatgta cttttactaa ccatggggat tctagaccag cttgtataat
     5521 attattttca tttataaaca cattttctgc ctttccttca tcaatcaaaa tccccttatc
     5581 caatacatat atgtaatcac atatttcata cattaaattc atatcatgac tggatattac
     5641 tatttttata ttatttttat ttaatccctt tattatatct acaatagacc tagtacttac
     5701 tgggtctaaa ccagctgtag gttcatcaag taatacaatt tcattttcca ttgctataac
     5761 tgatgctatt gccactcttt ttttctgtcc atagctaaga aaatgtactg gcctgtctat
     5821 aaaatctatt ccattaacag ctactagagc tttgtttatt ctctctttaa ttgttttttc
     5881 atccatacca atgtttctca ttgcaaaggc tatatcatca tatacttttg aataaaaaat
     5941 ttgtttttct gggtcttgga acacaatacc tacatttttt ctaaggttgt ataaacttct
     6001 cttatcatat tttaactttt cttctttaaa aagaatttct ccagatgtag gctttaatat
     6061 acccattaaa ttcataaata atgttgattt tcctgaacca tttgaaccta ttatacctat
     6121 aacatttccc tttgaaaaat ccatattaat gtttaatagt gcattggtat ttttttcata
     6181 ttgatacgtt aaattattta ttttaaacat cattatcccc tactatgtga aatttaccat
     6241 catacaattt tatgtctaat gatatacaca tatcatcata ccttgtcata agtcttttgt
     6301 acagcatact tccaagaata cctaaggatt tatatgaagt ttttaaattt atatatccaa
     6361 atcttagctc ttgtgacttg tatatttctg aaaattcttc taaaaatatg aatataaacc
     6421 tatatattaa cattgataac tcgacaaaag tgtcaggtaa atgaagtttt ttaaaaaaga
     6481 atattaattg attaaaaggt gttgtaagta tacaaaaata cacacaagtc aaacaagaca
     6541 tcgctctaaa taacacatga atagacatgt caatagacgc ctttgatatt cctacattaa
     6601 aactaaaaaa ttcaaaacta tataataaat ctgctttatt aaaagatata tttacaagag
     6661 ttattcctat actaagaaat aaaaagtaca ttggtattct aagtaatttt aaataatttt
     6721 ttaaatctat tccagccaca caaacaacca aaatactcat taaaatcata attccactta
     6781 aaataaatat attttgtatt accatagaag caatcagaaa aattactcct atggctactt
     6841 ttttgtttgg atttacttta ctcaatctat ttgtatatgc atatttatca attataagca
     6901 tgattaactt ctctttcctt tttgaagacc taatatgtat cctattacac cagcccctaa
     6961 agctgcttgt gcagagaata ataaactttc tatttctcca cttggtggct catatggact
     7021 gctaaaccat ggtttgtaat ttggatttat cttagtaatt tcactttcag cttgaccatc
     7081 tgctcctcca tattcagcac ctgagttgac aagtaatggg aatataataa gagctactac
     7141 taataaaagt aataatatgt tagtttttgt ttttgtttta gcactcatta gctttaactc
     7201 ctttatcatt attttctagt atgctttttt ctccattttc tgtaattaaa ttatatacaa
     7261 ttacagtaag tataccttct gctattgcta ttggtatttg agtcataaag aaaattccta
     7321 aaaacttaat tgctgaagcc atcactccac ctgatgggtc tgggaaagcc aatgctaatt
     7381 gtattgaggt tattgtatat gtagccaaat ctcctattgc tgctgcaaga aatactggca
     7441 ttgcattatt tccgtctttt ttctttaaag ccttaaatat taggaatgat acgattggcc
     7501 ctattatcgc cattgaaaaa gcattagctc ctaaagtagt tattcctcca tgtgctaaca
     7561 acaatgcttg gaatattaaa actatagttc caagaacaaa cattacgctt ggtccaaaca
     7621 ttattgctcc aagacctaca ccagtaggat gtgaacaact tcctgttact gaaggtattt
     7681 ttagtgctga taatacaaac acaaatgctc cacataaagc taataatact ttctttttag
     7741 ggtcttgctt tactatttta cctattgatt ttaatccgaa taagaaaaat ggtataaata
     7801 taactcccca tgctatagac cattttactg gtaagtaacc ttccattata tgcattgcat
     7861 ttgatgtaac tggagttaaa atgattaaca taagtgcagc tataacccct aatttaatat
     7921 tctgtttcat cttagtatcc ctctctccct ttctaataat taaaacataa taatacatgt
     7981 ctgatttatt taatcaaata aaaaagccta actcgatggt taggcttcta attttccaca
     8041 atctaaatac aaacacataa aacaaacata tctgtataat tattataaga aactttctcc
     8101 atccccgaag aaattacttt aatattttag gcaggtctcc tgacttagct tcatcctact
     8161 cctcttcctt cccatgagat ataaaaaata tcatcatagt ggctaacaaa agtttcgtct
     8221 gcatcacagt agcgggggct gtaaaggaat ttaacctttt tccctattaa tcttgcttaa
     8281 agaacctata atattatata tttaattttt aaattattct taaatcattt tctatataaa
     8341 tcattgtata ctttttctgt gaaaatttct acatttttta taaattttat tcatttttat
     8401 atttttatgt atataaattc ttttttgtaa gtttattaat ttctaattat cttctttaaa
     8461 tacattgaaa ctacatcaga aaatctagtt atatctcttg aatatataaa atcatttcca
     8521 tatattaatc tttcagcttc aagttctgat tcttttcctg taaatactcc taatactaat
     8581 atattttgct ttctagcttt tctcacttca ttggctgtat ctctcaaacc aactataccc
     8641 ctataagcct tttctcctct taatgttctc tcactacttt ttcctatctt tacatcattt
     8701 ggtcttccat cgctgagaac tatcaggatt ttattttctt catctctatt tattagacca
     8761 ctacatatag attttattgc caaaccatct ctattattac cagcacaaaa atattcaaat
     8821 atattttcac tattttttat actatcatca taatctttaa atctttttaa tattgtatag
     8881 tctaaaaagc tagaaaatcc catcactcta tttggtatgc caacttctgt tagagcattt
     8941 gcaattatgt aagcttgaat tgccacattt ccctgatttc tactttgaga gccacttgca
     9001 tccaataata tatcaataac gtatttccct ttttcatttt ctatatcttt ataaaatatt
     9061 ttattattat tacttctacc aactctccaa gctctatttg ctaatatagt accacaatca
     9121 gaatatactc tacttttagc attttcttct attaaaattc ttgatagact ttcttttaat
     9181 ctctttattt gctgtctata cattctagca tgttctctaa attttcctaa attattttct
     9241 ttttgtcttg ttacatattt tagttgaaat acattattac actcacttct aagaactcca
     9301 tctgtaaagt gtattctaca accttcatga acatttctac aattttgtgt ctcaattttt
     9361 ttaatttcac ctttactcaa ataagttttt ccataataat gttctatttt tgaatatatc
     9421 ttatttgcag tgtcttcatc aacatatata actcggtctg ctgaattgtt acatttagaa
     9481 tcatcaaaat cccctacacc ttctacaagc atggatgaag atattgaatc tatatcactt
     9541 tcaataatat tttcttcttc atcactataa agttcttcat acatgaaatc agcaaatgta
     9601 tcaaaattta cttctacact ttctacatta ttttcatcaa taagactatt ttcttctcca
     9661 tttaatatgt attcaaaata agttaaatat ataacatcta atgcttttaa aatctccata
     9721 atatcttgat tggtatctat atttcttata tcattaacta ttcttctagt catactatct
     9781 aatgctgggt gcttgtccat actataaagt acaaatgtgt atttaatttt atccataata
     9841 ttatcattgt gtattttggt aaaacgtgaa acaatatctt tataagcatt tcttcttatg
     9901 tcttctatcc ccggcctatc tttaatgacc ttttcttcaa ctattgtatt taatataact
     9961 tgaattagac ccagtataat atctttgttg tatccttttc ttattctatt tgtaagatat
    10021 tttttaacta tatcccaatc tacatacttt cttctagcac ctgcaattat tgcaaaatat
    10081 agacctattt cttttgaaga gtaatctttt tctgatatat ctatactttc attgtaatca
    10141 ccagctattg tccatgataa gttattagct ctattttcaa attcataatc atcatatatc
    10201 catttcataa tctcacctat attaaatatg acttattgga aacacatcta tactctccca
    10261 tttattaggt attctagttt taattacatc tccaaccatt tctttctcat atacatcaaa
    10321 agtctttcct gtaagtccca tattaattgc aagagttggt tttaatcctc ttcttatagt
    10381 cttaagagat gccataagac cacgtaaatc aatagcttta ctagatatct ctccattttg
    10441 agacttcaat tgtaaatcta aaaatattcc tgcaaagtgt attaattttt cttcatcagc
    10501 atctgaaaat tcatttttta aaatcatcat taacttatct tcttctatag gaggaatatc
    10561 tattaccata aatctagata ccagtgcttc attaagttct tttgttcctg catattcata
    10621 attcatagtc ccaataaatc ttgttgctgg atgtagattg actctctcat acccaggtac
    10681 atcaattatt cttctatagt ctaaagctga atgtaccaca actatagcat cattttttgc
    10741 catattaatt tcatcaaata ccccaaaacc tccattaata gcacactcat aaactgagcc
    10801 tcttctaagt ttaacttcat tgtctataaa tgtatctgta cctataagtg ttgaactgtc
    10861 tgtatttata tgaaatgatg tattccactg aggtctatta aatatttccc ctagattatc
    10921 agcaagtaag ttttttcccg ttgcctttgg tcccgataat aatatatttt cttcttctaa
    10981 aatagctgct atacacatag acaagatatc tttaccataa aaataagttt tagactttgt
    11041 tactctgtat tctaaatctt tttctaaacc ataataattt ctaaaataca gtacatcttc
    11101 aataagtttt tcatctaccc cttgcaccct tagattatct attatatcca tatttttacc
    11161 ccttttatat aaatagtatt tgtttcattt cttatcacca ttttagcata aaaggatata
    11221 agctaaaatt gattttttaa tctcccccat tttaagtaaa accatgcacc attttatcac
    11281 tacaaaatta agagtactac ttactgatat ttcttgattt tgttcgtcta tacgtatata
    11341 atatatgctg ataaattatg aggaaaggat gattgaaata tggaatatat gtcttgccca
    11401 gaagtagcaa aaaaatgggg tatttctgaa agaagagtac aaaaactatg tgaagaaagt
    11461 cgcataccag gagtttcaaa actcgggtat atgtggctga taccaaagaa cgcagaaaag
    11521 cctgttgatg gtagaacaaa aagaagaaag gaagtacaat atgaatagcg ttttgattat
    11581 agatgatgac aaagaacttt gtgctcttat gaaaaaatgt gttgagcaag aaaatttatc
    11641 tgctattact gcacattgtg gtgcagaagg tctacatttg gtcgataaaa atagacacac
    11701 actctctctt gtaattttgg acataatgat gccagatata gacggttttc aagttctgaa
    11761 aaaaattaga gaaacaagta atattccagt aattatgctt actgctaaaa atgacgagga
    11821 tgataaagtt tccggactac gtttaggtgc tgacgattac ctaacaaaac cgttcagcat
    11881 aaacgaactt atggctcgtg tcaattctct tattcgtcgg tatactatgt taaaccctgc
    11941 ttttataaca gacacagatt gcataataat aaatggcatg attattgaca agacaaaccg
    12001 aattgtttct gtcaataata ttcctgttca acttacaagc aaagaatttg atttacttgc
    12061 ttttctggct tctaataagg gacgggtgtt taccaaaaaa cagatttata cacaagtatg
    12121 ggaagaagaa tatgcttttg acgatagtaa catcatgtct ttcatcagta aattgagaaa
    12181 aaagattgaa ccagacccca accatccatt ttatattttg acagttcgtg gtgtcggtta
    12241 tcgttttaat aaggaggctt aacatgaata caagtgtcta tctgcttttg atattggctc
    12301 ttagcctgat tattatagcg taccttgttt ctgtcctgct acgtgtccga atacaactta
    12361 cacttataaa agatgcttta gaggatataa aaaatggaaa ccttaatcga cgtattttaa
    12421 cagatgaaaa cgacattaca aaacaaattt gctatgatat taacgaaata gcaatcaata
    12481 gccaatttca acttattcag caaaaacaat cagaacaagc ctacaaacag ctaatgacaa
    12541 gtctctccca tgatgtaaaa actccacttg cttctttggt cggttatttg gaagcagtag
    12601 aaagtaaaat tgttgtagga gaggaaaaag acgagtatat ccatgttgcg tctaataagg
    12661 ctcattactt aaagaatttt gtagaaaatc tatttgaatg ggtaaaattg gattctaagg
    12721 aacaagtttt tcattttgat atttttgact tgaatgaatt atcccgtaat attatatctg
    12781 attggatacc tgttttagaa agcagtcatt ttgaatatga atttgatata ccagaaatag
    12841 agtacttctt acgtatagac gcaaatgcat atacccgtat cattaataac ctattacaaa
    12901 atattattac ccatagtagt ggcaacaaaa tgacattgag aatttttgaa aacaaagagc
    12961 aagctcaaat tataataaca gataatggga aaggtatatc ttcagacaat ctcccacata
    13021 tttttgaaag gttgtaccaa tgcgaccatt cacgagcttc aaagggaaat ggtttaggct
    13081 tggcgattgc aaaggaactt attaacgctc ataagggaaa tattaccgcc aacagcactc
    13141 ccggtatggg aacagaattt acaatattgc ttcctaaagc cctgtaaaag tacgaggctt
    13201 tcttactcta aaacaagata aaagcaagat tatggcaagg ttttggcaag gttcatgttt
    13261 tataattcta attgtagttg attttgacgt tgtatcaact atcttttgta gaaacaaatt
    13321 tattaaaagt gaggaaatta tatatgaatg attttgtgat tgaaacaaag caacttacaa
    13381 aaatttatgg gaatcaaaca gtagttgaca aagtcaatct ccatgtaaaa aaaggccgaa
    13441 tatatggtct gttaggacgc aacggggctg ggaaaaccac aattatgaaa atgattttag
    13501 gattgacttc aatcacgtat ggcgaggtag atgtatttgg agagaatatt aagggacgtg
    13561 aaaaacaagt atatccccgt atcggcgcaa ttatcgaaac gccaggattt tatcctaatc
    13621 tgacaggaac ggagaacttg gagatttttg caaaactgcg tggtacagcc gcccctaatt
    13681 ctgtaaaaag agcattggag attgtaggct taccttataa aaataaaaag ctgtttagta
    13741 aatattcact tggcatgaaa cagcgacttg gtattgccaa cgctatcctg catgacccag
    13801 aactgttagt tttagatgag ccaaccaatg gtcttgaccc tattggtatt gcggagatga
    13861 gaaagtttat tagggacttg agcgttgagc atggaaagac aattcttatt tccagtcata
    13921 ttctttcaga aatctcattg ttggctgatg atattggaat tatcgaccac ggtgttcttt
    13981 tggaagaaag tagtatgagt gaactagaaa agaaaaacag taaatatatc ctgctacaag
    14041 tttcagatat tccgaagaca tcacttattt tagagcgtca atttaacacg aaggattatt
    14101 ccgttcaaga tgactacacg ttacaccttt ataacactaa tctggatatg ggtgaaatca
    14161 ataaagcact tgtaatgcag aatgtaattg ttattagttc tcaactttgt aatgatactt
    14221 tagaggacta ctttaaaaaa atcacaggag gagagggcat tgcttaaact tattcaaaca
    14281 gaatttctta aactgcgtcg taggaaactt atttggctga tgttgttgtc tgctctcatt
    14341 atgccgtttt tcgcactact atacttcaat tattttggta aaacaggtgt tgagccaaca
    14401 aagttttata aatggtctgc atttggttat acactttgga ttattttgcc cgttgttttg
    14461 ggtatatttt gcaccatgct tatacacgaa gaaaaccagt atgatatgct caaacagctt
    14521 tggattgtac ctattagtaa aatgggatac ttttttagta aatttttcgt tgttttgatt
    14581 tactctattt gttttatgct gattacagcc gttgcttctg tgttatttag tgtactttct
    14641 ggatatgtcg tatttagctg ggcaagcatt ttatatttgt tgaaaaaatg tttagaaatt
    14701 ggtgtaatca ctgcttttgt aatgttgccg attttggcaa tcgctacatc tcaaaaagga
    14761 tacattctcc caatttgtat cacattggta tatgcctttt ccggttttgt tataatgaca
    14821 ataaatatgt atttacaccc attatccagt atgggagtta ttatcatgag aaataaagac
    14881 attccaggtc ttatattttc acaggaaatt aatgtcccat tagcatttct ttgtatttgt
    14941 atttggagta ttgtatcagt attgtttgca aacattgcac taggaagaag aaagtgaggt
    15001 gtagataatg tggaaattac tttgggctga atgtcaaaaa attcgtcgtt caaaaattgt
    15061 ttggattaca gtttttgcat ccattatgat agcagtcata gtttttgcag gagggcagga
    15121 tgtatataat gacccagatt tacattatgg cttaaagagc gtttatgacg gttcacggta
    15181 tatagacaat gcaggttggt atatggacgc agtacaacct tggtcaactt tttttgttct
    15241 tcctgctgtc attgccctat taggaagcta tattatttgt cgtgaagaag aggaggacac
    15301 tattaaatcc ctgcgtctta ttcccataaa tgaaacaaaa ttaaccatag caaaaatgat
    15361 tattactttt atattcagta tacttcttta tttgttactc tttactataa catttttgac
    15421 tgaatccgtt ttacattttt ctgatttatc gacaaaactg gttttaagtt gcatgaaaga
    15481 gtattttctt gatggcatag gtgtattctt tgcaatttct cccattattg ccttggtatc
    15541 gcgcatgaaa aaaggatatt ggcttgcatt agtattcaca gaagtttatt ctattgctgg
    15601 actatttgcg ggtatgtcaa atgtcttaca aacctttttt cctattgcgg caatatttaa
    15661 tatttctgga tactatataa ctactggaga aaaaattatg gggagtatca taagtttatt
    15721 actttgtgcc tgcctttctg catttatact taaagggcta aaacacaatg aaaaaaattg
    15781 aaataggtat atcaaaatga aaaagataaa aaaactgatt attctaattg tattcttgtt
    15841 tctttttggc atgttacact gttatactga atggaaattc aacaataacc cacctaaagg
    15901 ggtaatagaa agaataaatg agtggactga taagattgga ctggattagt aacttatgtt
    15961 aattatagtg aatgtaatat tagcaagtta ttgtttcgta ttttaatact ataactttaa
    16021 atatttggtt ttaatcttcc aaacgaatat aaaaaaactg tcacagaggc aacatatttt
    16081 tgaatattta taaagtggta gttttgattt tcaaagctgc cgccttttct tctatataag
    16141 caaacttatc ctcaacaaag tgtaaaacat ggtacatttt aagaaaaaag taccacagac
    16201 acaagcaata aaagaaacgc cgagaaccta caaaaacgta gtgcttatgc agatttacga
    16261 cgccttctat tttctcaacc gtcttaatga ccttgtacaa aagaaatttt tctaatattt
    16321 tttataatct tatcttgtga tgttttttat gtataaatga cttaataaca aatccaataa
    16381 aaattatgga tattggtata attagaacga ggaatttata atcattataa tgtgacatta
    16441 ttcttaccca actctcagaa aaaatatatc ctatactgat taatgaagta ttccatatgg
    16501 ttattcccac gatagatgat attacaaaag ttataatatt ttgacctgct atacctgcta
    16561 taaaagatat gtatgttcta cataaaggga ttaatctaca tacacaaaca gaaatagaag
    16621 agtatttatt aaaataatct tgagatgcaa atattccttt ctttgccttt ggacatatct
    16681 ctattatttt atttatgata gatttacctc cccaatttcc cactgtataa caaaatatcg
    16741 aaccaagtat acctgcaatt atacttaaaa ttaaaattgt cagaaatcca aaatgatttc
    16801 ttgcagcaat tgctccacat aaaggtaaaa caacttcgct aggtaatgga aaacaagcat
    16861 actcaatcat aattaataca aatacagaga ttaatccata ttgtaaaata aaactattga
    16921 ttacagacac ttacttatct atctcctttc ttatttaaag gttttaaggg tacatgttct
    16981 aaggattctc accctatatt taaagaatca atctctttaa actattatat gtatttacac
    17041 aaagcattta taacatactt taaaaatagt accttaaaat aagaaactta ataaa
//
LOCUS       DAEORM030000071        16370 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.073, whole genome shotgun sequence.
ACCESSION   DAEORM030000071 DAEORM030000000
VERSION     DAEORM030000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 16370)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16370)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 16370)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16370
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.073"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            29..2647
                     /locus_tag="KRH23_003243"
     CDS             29..2647
                     /locus_tag="KRH23_003243"
                     /inference="COORDINATES: protein motif:HMM:NF038316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DrmE family protein"
                     /protein_id="HHS5226517.1"
                     /translation="MLTTNIHYILDNDICEIYFNKQRLTNSKYYQDNINVLNYIINEK
                     NNNLIINYNDKYIYAIYLLNIAINSYLNNTLNPNNHILTKLDKGMPLLYKGQIVIFKN
                     INNTHITLGHKNKTDTTLIPIDSAYMLITYNGHLEVNSMGKTPASKTFQTKNVLSSLG
                     FSDLKNMTGVINDSTLIILPCKDDISDLVSNIKIKDINNTYKFTELFPCSYISSTGAE
                     TDYPGNHAKQIPLLKFTTNISSAFEIIKSDKSIKNVFIIGDYPIYKHINDFERILNRK
                     RIESVNIVTSNSNISNILDLPNIDNLNIYSWSKDVLLTYSQDFENTSTFQKLWLDKLI
                     NKNICTTSVDSNISDLIHQARKSLYYISKYDFDISIKNSLMMCSYSLLKILENTPFNL
                     DFLEETIKLLNLNIATPSAKLENIKYLISSTSPDLELSALFDDVIVKFERIINELSDN
                     NTKFNTLNKLVSSYKYKTFTPNTPVILLQKQYEAIILKNLLKSRNINLQVISAEKFKD
                     SKTIKNLIMFGFYDLKYLDILNSDLIINITLYLYNSELSKYNYYMNQINSARNKIEKN
                     NKIYNLLDIKPFKPTYETNKLEAYSTDSPISDDDSMDEYISNYKFDINLNEIILSLSI
                     NQGIYNSKKEHVTSFMISDNNEYIFCTKKAIAYSIDWDKKSVRKKKLSEAKVNDWFLF
                     VDDYLNEEGELVINVIQKLLELNLLPSHYLDDYKLTNSWKSELKNYISYSKYNYNDVS
                     NSLAVLGEKINPITIKNWVTNKRLIGPIYLKTFEKIFKVIDSKLDHTEVYDATKSIRS
                     LHTKIKKSIDTFVSDNFFSSKSDIIKDEVSAVVLSMLGNTNDYVTPVQIREIHSCDKY
                     LSPHLVNKVLDLYSVY"
     gene            2665..6192
                     /locus_tag="KRH23_003244"
     CDS             2665..6192
                     /locus_tag="KRH23_003244"
                     /inference="COORDINATES: protein motif:HMM:NF012493.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-related protein"
                     /protein_id="HHS5226518.1"
                     /translation="MNCSELRDKTLDLVRKELLGPGSEDLCENIKYEIITDSPIERYS
                     TGILYPLNNNIDVSNTSEYDGEDNVFTSDDTQNELDRAISMSNETLPSSMGMTFFLKK
                     DAEVINFRVNYATYRNALYTDCHVKYTGDDFYSSNTINEYVELRGSFLYLKQKLTSEK
                     VYNLLKKHDLLDNAEAKFVLYKLANQCPDDENKTGGYVRVPHENLIVSIDMDKNYIKK
                     PISKDLDIVLSKRIYSNDFVSITCMLVNSQSGPKKYNNTIFQPELMVLAEDNNDLEFI
                     DIFTAGSVNTFKKLDSEEISLDLLYRNKKTFATGHGVAIDQDIQNDALIKLCTEFIPH
                     FEVPKLDFNVDELSDVSRELLSMKNLSDISDLSKDKKIYFLYKFVDAYDIWIDDLEED
                     SKDLSDVFKDVAYEHIKNCRDTKSRMLEGINLIKSNDEVYRAFSLMNRAILMQRCHSI
                     HITDRLPGSNNLDYIDYSNDNSAWRPFQLAYILTCLSSIENPDSKHRDLVDLLWIPTG
                     GGKTEAYLGLSAFTIFLRRIRNKENGNGTAIIMRYTLRLLAAQQFIRASILICACEII
                     RKENKSELGKKEISIGLWIGSDQTPNFNDEAEEMLNNLTGNNIKFRSSINSEYELDNL
                     KSKYNKFQLLKCPWCGTKLVKEWDKTSKKAVGDWGYRIKSRPKKFYLCCPEEDCSFED
                     MLPIQVVDEEIYNNPPTLLFGTVDKFAMITWTTEVASLFALDDDNSNLSPELIIQDEL
                     HLISGPLGTMVGLYETALDAMCSYKGIKPKIIASTATIRKAQNQVKNLYNRNVAQFPP
                     PGLTSSNSFFVKEMPLSKKRGRLYVGVIPSGKTQVTVEVRLMSALLQRLKMMENVELN
                     LLDKYWTLVSYFNSIRELGKCSTLLNDDIKDNMERLCKRVSAHPYQSLRNLNEQRELT
                     SRLTSTKINTTLDELSNTLTSNNLTVDTLLASNMISVGVDVDRLNLMVVVGQPKLTSE
                     YIQASSRVGRSNEGLIFTLYNPTKTRDRSHYEQFFSYHQSFYKFVEPTSITPFSEPAR
                     ERGMHAVLISMIRHILGLQANDLASRFSKNMDGVEDLKNFIIDRSIDIFRENNQNADD
                     NIVNEFKSEISSELDIIMDLWHDKAQISDKDNLLHYYKRPSKFDNKIYNNLLIPYDKD
                     VITNEKQTLNSMRNVDKQCTVEIIELEEN"
     gene            6194..8107
                     /gene="drmB"
                     /locus_tag="KRH23_003245"
     CDS             6194..8107
                     /gene="drmB"
                     /locus_tag="KRH23_003245"
                     /inference="COORDINATES: protein motif:HMM:NF038324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DrmB family protein"
                     /protein_id="HHS5226519.1"
                     /translation="MSIKLDDKTHNLRINQATSVFGPGAMLDFIDQTLMTAHPNYWTN
                     TIKIQDDRLQATLRVNELRTPPTIDDRSSVPFVRFPRWYFCPKCRKFMPIEDWEKLYK
                     NAHKDKPMKIPICLTCSTKKSTKQLVPTGIITICEHGHIDDFPWVKWVHFRNKSGRKE
                     ICENPQILMKTGKSNLGLEGIELECSCGAKANMKGAFMRLKSSKSNDYGVPNEYKEMF
                     KCSGNSPWYNKKVNKCTKYSFASQRGASNVYYPKIESSIIIPPYSDTLNSKVLSSKGY
                     DTFKKFLDRAIEKNKLECFMDEDFEDFASDIAKETGFDTDKISIVLKDLLPFEDSSPS
                     TTTRNQYREEEYEALIGNIDAKSKKTNDFTIEEQNLSDYDIPNFSKIVLVKRLREVRA
                     LTGFSRVNPPDNNIFGEEDIDDSCNDTKVISLRSRDCKKSFYPASEVRGEGIFIEINN
                     DMVKSWISSNPKIQDNASILNSRYNKDINVNDKAYRKITPKFLLLHTLAHLIIRELSF
                     VCGYATSSLRERIYCNNSENEKVMSGILVYTASGDSEGTLGGLVRQGMHDSLPSILNS
                     ALNRALWCSNDPICIDSTGQGRNSLNLGACHSCTLLPETSCEEYNLLLDRSMLIGDMD
                     NRDIGFFKNLILI"
     gene            complement(8802..9545)
                     /locus_tag="KRH23_003246"
     CDS             complement(8802..9545)
                     /locus_tag="KRH23_003246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226520.1"
                     /translation="MSNKGWIKLYRELLDKSIWKDIKPERKVILITILLMASHKENHV
                     FIDNKRIKIKSGQFISSYSKIAERCGKGVSYQMVRSCLLVFKNAGFLTYETTNKYIVI
                     TIENWELYQENIENQQPNQQTINNQSTTIKNIKNENNIIYSEIISKFNSTCIELSKVK
                     KLTDTRKRRINSRIKEYDKETVLEVINIVSKTSFLNGNNNTGWKANFDWIMNSSNFTK
                     ILEGNYNSKEIVINKETGIYNPDDSQLKW"
     gene            complement(9567..9881)
                     /locus_tag="KRH23_003247"
     CDS             complement(9567..9881)
                     /locus_tag="KRH23_003247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226521.1"
                     /translation="MKENNNLEVLKTLQATLNIIVKNEEEAQEKKQGYKIIENAKRNK
                     AELITCKEASKLYPIGESKFRQLCHSKNKGFPCIWINNRVYIIKNKLDDWFIENANGI
                     KL"
     gene            complement(9885..10085)
                     /locus_tag="KRH23_003248"
     CDS             complement(9885..10085)
                     /locus_tag="KRH23_003248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HHS5226522.1"
                     /translation="MGINLKIFRIKKGLKQQELADRVGISRYYLSNLETGKANNPSND
                     LMIKLSRALDTTVEELFFSKED"
     gene            10223..10996
                     /locus_tag="KRH23_003249"
     CDS             10223..10996
                     /locus_tag="KRH23_003249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHS5226523.1"
                     /translation="MIILQIGKNLKNIRKQKELTQIQLAEISGISRNALINYENDKRI
                     PSIDTLSKLAKALKIEKTIFYFDIENEVMTNEDVLYFLQSLFPEEYYSFDEFLNAISN
                     LMEDDDIRITSSLLLGAWSDKDQYYKLGEKLELNENQVYNWILSDCISNTELDFSLHP
                     DDIKEIIKNDVLTKQSIDELLDIGLSEENIETIYDYFSDPTDTGSNIRLKKLISQKEN
                     ITIKNNDYFKLLQENNELKEKNEKLENTLKEIKKLLTKI"
     gene            11053..11250
                     /locus_tag="KRH23_003250"
     CDS             11053..11250
                     /locus_tag="KRH23_003250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226524.1"
                     /translation="MNKSYMLKYTYKSPTNLFHGDKKYTLTYTKRVMSNLVYDMDNLE
                     NNSFTCLEVQSLFDDIFKVKL"
     gene            11250..11738
                     /locus_tag="KRH23_003251"
     CDS             11250..11738
                     /locus_tag="KRH23_003251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHS5226525.1"
                     /translation="MNNTIGEKIKQYRKSINMSRDELANKIGCSVHAIAKYEQNQRMP
                     SLDMIRKIATALSIAINKLIVEENDLDTLTNNNINLKVFNKEFDLVIHILENYDYDIK
                     TDYKTKFEITDNVDTIKPINLNFSDFKNFSKNLNWVINGLVENFIQENSNGLIENEDE
                     EY"
     gene            11827..12579
                     /locus_tag="KRH23_003252"
     CDS             11827..12579
                     /locus_tag="KRH23_003252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HHS5226526.1"
                     /translation="MNKSYIPKYTYKFPTNLPHGDKKYTLTYIRRMISEFVYDMGKLE
                     NNPFTFPEVQTLLDGITVGGHKLSDQNQILNIKSSWDYVIKLSNKENLSLNKDTICSI
                     HKIVAKDEALIVGDFRNGNIGIAGTTQYECIEATLLNDLFVNDINIINKITNPLEKAI
                     IINLWLSYCQFFYDGNKRTARLTSNLILISNDIGVLSIPAKHKQEYNTLMLNFYETLE
                     ADEVIKFLLEKCITFFDGYKYKSYKELFKNGN"
     gene            12569..13735
                     /locus_tag="KRH23_003253"
     CDS             12569..13735
                     /locus_tag="KRH23_003253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009009 - site-specific recombinase
                     activity [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HHS5226527.1"
                     /translation="MATKRANGEGSIGKYKDGWRSRIMIGYNEDGKPIRKEFYGKTQK
                     EVKDKLDAYKKQYYLSSDISDDKITLEHWFYNWLFEYRIKDLKPKSFERYESIYRNYI
                     KDTDLGNVKLKDLRVSHIQKYYNRLLDSNKSIPTIRQINTKLKTCLSEAEKQGLIQRN
                     YCTMVNIPVEKKENKLEILTLEQQKSFIKAIDGHKLEVLFLLALGTGLRLGELLGLKW
                     FDIDFKKSNLTVKRTLQRTYFIDKTGNRELKVLEQGPKTSNSYRTVPIPKDVLNKLKE
                     HKVNQNTDILKAGELYINNNYVFCNELGIPIDDKRPLRNLRSILNSLNIEPIKFHGLR
                     KTYATRLFENDFPPKTVQVLMGHYDISITLNIYTQVMEDKKVEAVEKLDKIFSL"
     gene            complement(13851..14081)
                     /locus_tag="KRH23_003254"
     CDS             complement(13851..14081)
                     /locus_tag="KRH23_003254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226528.1"
                     /translation="MEANKTLLQILYKKIILEFSKQTGKSLEESMDYLYTSETYKLIS
                     EGVSDMHCKGHIYLAQELMLENGLMYHKGYPR"
     gene            complement(14087..14566)
                     /locus_tag="KRH23_003255"
     CDS             complement(14087..14566)
                     /locus_tag="KRH23_003255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3990 domain-containing protein"
                     /protein_id="HHS5226529.1"
                     /translation="MIVYHGSYCVVKTPSITFSRDSLDFGKGFYVTSIKIQAINWTER
                     FKKRGKKAYLNSYSLDIDKLKENCKVKIFNSYNLEWLDFIIECRNMSDIYMKYDIIIG
                     GIADDKIYNTIELYQDNLIEKDEALKRLKYYKPNEQICITNQNVIDKYLKFRCEEEV"
     gene            complement(14566..14781)
                     /locus_tag="KRH23_003256"
     CDS             complement(14566..14781)
                     /locus_tag="KRH23_003256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3791 domain-containing protein"
                     /protein_id="HHS5226530.1"
                     /translation="MDERKLEFSIFCIEALAEKLNIDSEGVYKLLKHDTDILDNYIIP
                     CYEALHSQSKGYIVEDLMQVLKEKGVI"
     gene            complement(15129..15478)
                     /gene="ssrA"
                     /locus_tag="KRH23_003257"
     tmRNA           complement(15129..15478)
                     /gene="ssrA"
                     /locus_tag="KRH23_003257"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(15636..16091)
                     /gene="smpB"
                     /locus_tag="KRH23_003258"
     CDS             complement(15636..16091)
                     /gene="smpB"
                     /locus_tag="KRH23_003258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HHS5226531.1"
                     /translation="MAGKKILATNKRARHEYFIEETYECGIELKGTEVKSIRQGKVNL
                     SDGFASVDNSEVFLKQVHISPYEQGNIFNVDSLRVRKLLLHKHEIRKLIGATTIKGYS
                     LIPLSLYLKNGKVKVEIALAKGKKLYDKRQDMAKKDAQRRIEREMTGKY"
BASE COUNT         6160 a         2168 c         2217 g         5825 t
ORIGIN      
        1 acaatagtaa ctactaaagg agatttaaat gttaactaca aatatccatt atattcttga
       61 taatgatata tgtgaaattt attttaataa acaaaggcta acaaattcta agtattatca
      121 agataatatt aatgtattaa attatattat aaatgaaaaa aataataact taattatcaa
      181 ttataatgac aaatacatat atgctattta tttgttgaat atagctataa actcatactt
      241 aaataataca ttaaacccaa ataatcacat tcttacaaaa ctcgataaag gtatgcccct
      301 gctctacaag ggtcaaatag ttatatttaa aaatataaat aatacacaca taactttagg
      361 acataaaaat aaaacggata caacacttat acctattgac tcggcttata tgcttataac
      421 ctataatggt catttagaag tcaattctat gggcaaaact ccagcatcta agacttttca
      481 aacaaagaat gttctatcat ctttaggttt ttcagactta aaaaatatga ctggagtaat
      541 aaatgattct acactgatta tattgccttg taaagatgat atatctgact tagttagtaa
      601 tattaaaata aaagatatta ataatactta taagtttact gaactatttc catgttcata
      661 tatttcatca actggtgccg aaactgatta tcctggaaat cacgctaagc aaataccttt
      721 acttaaattt acaactaata tttctagtgc atttgaaatt attaaatctg ataagtctat
      781 aaaaaatgta tttataatag gtgattatcc aatttataag catataaatg attttgaaag
      841 aattttaaat agaaaaagga tagaaagtgt aaatattgta acctcaaatt caaatataag
      901 caatatatta gatttaccaa atatagataa tctaaatata tactcttggt ctaaagatgt
      961 tctgttaacc tatagccaag attttgaaaa tacctctact tttcagaaat tatggctaga
     1021 taaacttata aataaaaata tatgtactac ttctgttgat tctaatatct ctgacttgat
     1081 acatcaggct agaaaatcac tttattacat atctaagtat gattttgata tttccataaa
     1141 aaactcactt atgatgtgta gttactctct tcttaaaatc ttagaaaata caccttttaa
     1201 cctagatttt ttagaagaaa ctataaaact tttaaattta aatatagcaa ctccttcagc
     1261 gaagctagaa aatataaaat atttaatttc aagtactagc ccagatttag aattaagtgc
     1321 attatttgat gatgttatag tcaaatttga aagaattata aatgaattat ctgataataa
     1381 taccaaattc aatacactaa ataaattagt atcttcatat aaatacaaaa catttacacc
     1441 aaatacacct gttatattgc tacaaaaaca atatgaagct attatactta aaaatttatt
     1501 aaaatctaga aatataaatt tacaagttat ttctgctgaa aaatttaaag attcaaaaac
     1561 aataaaaaat cttattatgt ttggattcta tgatttgaaa tatttagata ttttaaatag
     1621 tgatttgatt ataaatatta cactgtattt atataatagt gaattatcca aatataatta
     1681 ctatatgaat caaataaatt ctgcaagaaa taaaattgaa aaaaataata aaatatataa
     1741 cttacttgat ataaaacctt ttaaaccaac ttatgaaacc aataaattag aagcttattc
     1801 taccgatagt cctatttctg atgatgattc tatggatgaa tatatatcta attataaatt
     1861 tgatataaat ttaaatgaaa ttatattatc tctatctata aatcaaggga tttacaactc
     1921 taaaaaagaa catgttacat cattcatgat ttctgataat aatgagtata tattctgtac
     1981 aaaaaaggca atagcctatt caatagattg ggataaaaaa agtgttagga aaaagaaact
     2041 ttcagaggct aaagttaatg actggttttt atttgttgat gattacttaa atgaagaggg
     2101 tgaattagtt attaatgtta tacaaaagct attagaactt aatttattgc catctcatta
     2161 tcttgatgat tataaattaa ctaattcatg gaaatcagaa cttaaaaact atatatctta
     2221 tagtaaatat aattataatg atgtatcaaa cagtttagct gttttaggtg aaaagattaa
     2281 tcctataaca atcaaaaact gggtaacaaa taaaagatta ataggtccta tatatttaaa
     2341 aactttcgaa aagatattta aagttataga ttctaaatta gatcataccg aggtatatga
     2401 tgctactaaa agtatacgct ctttgcacac taaaataaaa aaatctatag atacatttgt
     2461 atctgataat ttctttagca gtaaatcaga tataattaaa gatgaagtgt ctgcagttgt
     2521 tttaagtatg cttgggaata caaatgatta tgttacacct gtacaaatac gagaaataca
     2581 cagttgtgat aagtatctgt caccccacct tgttaacaaa gttttagact tatatagtgt
     2641 ttattaaata aataggaggt aaatatgaat tgtagtgaac taagagataa aaccctagat
     2701 cttgtaagaa aagaacttct tggacctggt tcggaagatc tttgtgaaaa tataaaatat
     2761 gaaataataa cagatagtcc aatagagcgt tattcaacag gtattttata tccacttaat
     2821 aacaatattg atgtaagtaa tacatctgaa tatgatggtg aagataatgt atttacatca
     2881 gatgatacac aaaatgaact agatagagct ataagtatgt ctaatgaaac tttaccttct
     2941 tctatgggta tgactttttt cctaaaaaaa gatgcagaag taataaattt cagggtaaat
     3001 tatgctactt atagaaatgc tttatataca gactgtcatg ttaaatatac tggtgacgac
     3061 ttctattcta gcaatacaat taatgaatat gtagaactta ggggatcatt cctatatctt
     3121 aagcaaaaac taacatctga gaaggtttat aatttactaa aaaagcatga tttacttgat
     3181 aatgctgaag ctaaatttgt tttatacaag ttagctaacc aatgccctga tgatgagaat
     3241 aagactggtg gttatgttcg tgttccacat gaaaacttaa tagtatcaat agatatggat
     3301 aaaaactata ttaaaaaacc tatatctaaa gatttagata tagttttatc taaaagaatt
     3361 tattcaaatg actttgttag tattacttgt atgctggtta atagtcaatc tgggcctaag
     3421 aaatataata atactatttt ccagcctgaa ctaatggtat tagctgaaga taacaatgat
     3481 ttagagttta tagatatttt tacagctgga tcagtaaata cttttaaaaa gttagattct
     3541 gaggaaatat ctttagactt actttaccga aataaaaaaa cttttgctac tggtcatggt
     3601 gtagctatag atcaagatat tcaaaatgat gctttaataa aactttgtac tgagtttatt
     3661 cctcattttg aagtacctaa attggacttt aatgtagatg aattaagtga tgtttctaga
     3721 gaattactgt ctatgaaaaa tttatcagat atctctgatc ttagtaaaga taagaaaata
     3781 tattttcttt ataagtttgt tgatgcttat gatatttgga tagatgatct agaagaagat
     3841 tcaaaagatc ttagtgatgt ttttaaagat gtagcatatg agcatataaa aaactgcaga
     3901 gatactaagt ctagaatgct agaaggtata aatttaatta agtctaatga tgaagtatac
     3961 agagcatttt ctctaatgaa tagagctata cttatgcaaa gatgtcattc tatacatatt
     4021 acggatagac tccctggatc taataacctt gactatatag attactcaaa tgataattct
     4081 gcttggagac cattccagct tgcttatata cttacatgtt tatcttcgat agaaaatcct
     4141 gactctaaac atagagattt agttgacctt ctttggatcc ctactggtgg aggtaaaacg
     4201 gaggcctact taggtctatc tgcttttact atcttcttaa gaagaataag aaacaaagaa
     4261 aatggtaacg gtacagctat cataatgaga tatacactaa ggctattggc tgcacaacaa
     4321 ttcataagag caagtatatt aatttgtgcc tgtgaaatta ttagaaaaga aaataagtct
     4381 gaacttggga aaaaagagat ttctattggt ttgtggattg ggagtgatca aactccaaac
     4441 tttaatgatg aggcagaaga aatgcttaat aacttaacag gtaataacat taagtttaga
     4501 tctagtataa atagtgaata tgagttagat aatttaaaat caaaatataa taaattccaa
     4561 ttactaaaat gtccttggtg tggaacaaaa cttgttaaag aatgggataa aacttctaaa
     4621 aaagctgttg gtgattgggg ctatagaatt aaatctagac ctaagaaatt ctacttatgc
     4681 tgtcctgaag aagattgttc atttgaagat atgttaccta tacaagttgt agatgaggag
     4741 atttataata accctccaac acttttattt ggtacagttg ataaatttgc aatgataact
     4801 tggactacag aagtagctag tctttttgct ttagatgatg ataatagcaa cttatctcct
     4861 gagttaataa ttcaagatga gcttcatctt atttctggac ctttaggtac tatggtaggt
     4921 ttatatgaaa ctgcacttga tgctatgtgt agctataagg gtataaaacc taagattata
     4981 gcttctactg ctactataag aaaagcacaa aatcaagtta aaaatctata taatcgtaat
     5041 gtagctcagt ttccacctcc aggattaaca tctagtaact ctttctttgt taaagagatg
     5101 cctttaagta aaaaacgtgg ccgactatat gtaggtgtta ttccatctgg aaaaactcaa
     5161 gttactgtag aggttagact tatgtcagca ttactccaaa gacttaaaat gatggagaat
     5221 gtagagttga atttattgga taaatattgg acactagtat cttattttaa tagtatcaga
     5281 gaattaggta agtgtagcac acttttaaat gacgatataa aagacaacat ggaaagatta
     5341 tgtaaaagag tctcagccca cccttatcaa tcattaagga acctaaatga acaaagagag
     5401 cttactagta gacttacttc tactaagata aatacaactt tagatgaact atctaatact
     5461 cttacttcta ataatttaac tgtcgatact ctattagcta gtaatatgat ttcagttggt
     5521 gttgatgttg atagattaaa tttaatggta gtagttggtc agcctaagtt aacatctgaa
     5581 tacatacaag ctagcagtag agttggtaga agtaatgaag gacttatatt tacattatat
     5641 aatcctacaa aaacaagaga tagatctcat tatgaacagt tctttagtta tcatcaatca
     5701 ttctataaat ttgttgaacc tactagtatt acacctttct ctgaaccagc tagagaaaga
     5761 ggcatgcatg cagtattaat aagtatgatt agacatattt taggacttca agctaatgat
     5821 cttgcaagtc gattttcaaa aaatatggat ggtgtagaag atttaaaaaa cttcataata
     5881 gatagatcta tcgatatatt tagagaaaat aatcaaaatg ctgatgataa tatagtaaat
     5941 gaatttaaat ctgagatttc atctgaatta gatattataa tggatttatg gcatgataaa
     6001 gctcaaatat ctgataaaga taatttattg cattattata agcgccctag taaatttgat
     6061 aataaaatat ataataatct tttaattcct tatgataagg atgttattac aaatgaaaaa
     6121 caaacattaa attctatgag aaatgttgat aaacaatgta ctgttgaaat tatagaattg
     6181 gaggaaaatt aatatgtcta taaaattaga tgataaaact cataatttaa gaataaatca
     6241 agctacaagt gtttttggac caggagctat gctagatttt attgatcaaa cattaatgac
     6301 tgctcatcca aattattgga ctaatacaat taaaatacaa gatgataggc ttcaggctac
     6361 attgagggtt aatgaactaa gaacacctcc aactatagat gatagatctt ctgttccttt
     6421 tgttaggttt cctagatggt acttttgtcc aaaatgtaga aaatttatgc ctatagaaga
     6481 ttgggagaaa ctttataaaa atgctcataa agataaacct atgaaaatac ctatttgcct
     6541 tacttgtagc acaaaaaagt ctactaaaca attagtacct actggtataa ttactatttg
     6601 tgaacatggt catattgatg attttccatg ggtaaaatgg gttcatttta gaaataaatc
     6661 tggaagaaaa gaaatttgtg aaaatcctca aatattaatg aagactggaa aaagtaacct
     6721 aggattagaa ggtatagaac ttgaatgtag ctgtggagct aaagctaata tgaagggcgc
     6781 atttatgcgt ttaaaatctt ctaaatctaa tgattatggt gtacctaatg aatataagga
     6841 aatgtttaaa tgctctggta attcgccttg gtataataaa aaagtaaata aatgcactaa
     6901 atattcattt gcttctcaaa gaggtgcctc taatgtatat tatcctaaga tagaaagttc
     6961 aattattata ccaccatact ctgatactct taattctaaa gtgctatcta gtaaaggtta
     7021 tgatacattt aagaaattct tagatcgtgc tattgaaaag aataagttag aatgctttat
     7081 ggatgaggat tttgaggact ttgccagtga tattgctaaa gaaacaggtt ttgatactga
     7141 taaaatatcc atagttttga aagatttatt gccttttgaa gattcttcac catcaacaac
     7201 aactagaaat caatatagag aagaagaata tgaggcttta attggaaata tagatgctaa
     7261 atctaaaaaa actaatgact ttacaataga agaacaaaat ctatctgatt atgatattcc
     7321 aaacttcagt aaaatagtgt tagtaaaaag acttagagaa gtaagggcat taactgggtt
     7381 tagtagagtc aatccacctg ataataatat atttggtgaa gaagatatag atgatagctg
     7441 taatgatact aaggttataa gtttaagatc tagagattgt aaaaaatctt tttatcctgc
     7501 atctgaggtt agaggtgaag gtattttcat agagataaat aatgatatgg taaaaagctg
     7561 gatttcatct aatcctaaaa tacaggataa tgcatctatt ttaaattcta gatataataa
     7621 agatattaat gttaatgaca aagcttatag aaaaattaca cctaaattct tattactaca
     7681 tactttagct catttaatta taagagaact tagttttgtt tgtggatatg ctacctcttc
     7741 acttagggaa cgtatatatt gtaataattc cgaaaatgaa aaagttatgt ctggaatttt
     7801 agtttacact gcaagtggtg actctgaagg tactttagga ggattagtta ggcaaggtat
     7861 gcatgattca ttaccatcta tattaaatag tgctcttaat cgtgctcttt ggtgttctaa
     7921 tgacccaata tgtattgata gtactggtca aggtagaaat tctttaaatc taggagcatg
     7981 ccattcatgt actttattgc ctgaaactag ctgtgaggag tataatttat tacttgatag
     8041 aagcatgtta attggtgata tggataatag agatattggg ttctttaaaa atctaatttt
     8101 aatttagtaa taactaattt tttatttata taactaaagg ttaaaagtta attttatgac
     8161 ttctatcctt tagttttttg tatttaaatt attatttttt gcaaatcatt cttactagaa
     8221 attacttatt ataactaatt cccaataatt atataatttt gtgctcatac tgaaattttt
     8281 aaataaacta ttaatttata ttatatatga tttttcaaaa taaaaaacat attaactatt
     8341 aaatcaatat gttttcgtgg attccaatgg tggagaccga ggagaattta taagtggtta
     8401 tttgattgtt ttgttggttt ttataagtat atgtatatgg ctatttggtc atgatgttga
     8461 agcaattttt ctggttattt tttattgtct atttttgtag ttggggtata attttctact
     8521 ttccaaaatt attgatactt caataatata aattaaattc ttagttaagt tttttaatga
     8581 ataggtaaat attatttgta ctcataacaa tatagtttac gcataatttt atatatattt
     8641 tctggtatat ctgcaactaa cttagtgtaa tttaaacgat attagagata cttaaaaaac
     8701 aaatatatga aagatttata actaacttag tgtaatttaa ttgattgctc tgcttctgta
     8761 tttttaatta agttgtttga attatttata atataacctc cttaccactt taattgtgag
     8821 tcatctggat tatatattcc tgtctcttta tttatgacaa tttccttgct attataattt
     8881 ccctctagta tcttagtaaa attacttgaa ttcattatcc aatcaaaatt tgctttccat
     8941 cctgtattat tatttccatt cagaaaactt gttttactaa ctatatttat aacctctaat
     9001 acagtttctt tatcatattc ttttattctt gaatttattc tcctctttct tgtatctgtt
     9061 agtttcttga cctttgaaag ttcaatacaa gttgagttaa atttgcttat gatttcacta
     9121 tatataatat tattttcatt ctttatattc ttgattgttg ttgattgatt gttaatagtc
     9181 tgttgattag gttgttgatt ttctatgttc tcttgataaa gctcccagtt ttcaatagtt
     9241 atgactatat acttgtttgt tgtttcgtat gttagaaaac cagcattttt aaaaaccaac
     9301 aaacaacttc taaccatttg ataactaact cctttaccac atctttcagc tattttgcta
     9361 tatgaagaaa taaattgtcc agattttatt tttatccttt tattatctat aaaaacatgg
     9421 ttttctttat gactagccat aagtaatata gttattaata ttacttttct ttctggttta
     9481 atgtctttcc aaattgattt atccaacaac tccctataaa gctttatcca ccctttattg
     9541 ctcaattaca aacacctact ttaagactat aacttgatac catttgcatt ttcaataaac
     9601 caatcatcta atttattttt tattatgtat actcgattat ttatccatat acaagggaat
     9661 cctttgtttt tagaatgaca taactgccta aattttgatt ctcctatagg ataaagctta
     9721 gatgcttctt tacatgttat aagctcagct ttatttcttt tcgcattttc aataatttta
     9781 tatccttgct ttttttcttg tgcttcttct tcattcttta caataatgtt taaagtggct
     9841 tgtaatgtct ttaaaacctc taaattatta ttctctttca tattttaatc ctccttacta
     9901 aaaaataatt cttctactgt tgtatctaaa gctctagata gtttaatcat caaatcattg
     9961 cttggattat tagccttacc tgtttccaag tttgataaat aatatcttga tataccaact
    10021 ctatctgcca gttcttgttg ctttagacct tttttaatcc taaatatttt taaattgatt
    10081 cccatacttt ttcctccttt tttctagttt acattcgtaa actttacatt ttaattataa
    10141 tgtcgatata tgtgtactgt aaataaaaat atattatttt tctgttctca tttgtgtact
    10201 tttgggctat actttatacg aggtgataat attgcaaatt ggaaaaaact taaaaaatat
    10261 aagaaaacaa aaagaactaa cacagattca acttgctgaa attagtggca tctcaagaaa
    10321 tgctctaata aattatgaaa atgataaaag aatacctagt atagatacct tatcaaaact
    10381 cgctaaagct ctgaaaattg aaaagactat cttttatttt gatattgaaa atgaagtaat
    10441 gactaatgaa gatgttttat actttttaca gtctttattc ccagaagaat actattcttt
    10501 tgatgaattt ttaaatgcta tttcaaatct tatggaagat gatgatatta gaattacctc
    10561 aagtttattg ctaggtgctt ggtctgataa agaccaatat tataaacttg gtgaaaaatt
    10621 agaactaaat gaaaatcaag tttataattg gatactttca gattgtatat ctaatactga
    10681 attagatttt tcattacatc ctgatgacat aaaagaaatt attaaaaatg atgttcttac
    10741 aaaacaatca attgatgaat tattagatat tggtctatca gaagaaaata tagaaacaat
    10801 ctatgattat tttagtgacc caacagatac tgggagtaat attcgactaa aaaaattaat
    10861 atctcaaaaa gaaaatatta ctattaaaaa taatgattac tttaaattat tacaagaaaa
    10921 taatgaacta aaggaaaaaa atgaaaagct tgaaaataca cttaaagaaa taaaaaaact
    10981 actaactaaa atataaaata atatcaatac tatctaaagc aatgataaaa aactatgaat
    11041 ggagttacaa ttatgaataa atcatatatg ctaaaataca catataaatc ccctactaat
    11101 ttatttcatg gagataaaaa atatactcta acatacacta agagagttat gagtaattta
    11161 gtatatgata tggataatct agaaaataac tcctttacat gtttagaagt acaatcattg
    11221 tttgatgata tatttaaggt gaaattatga tgaataatac aatcggagaa aagattaaac
    11281 aatatagaaa atcgataaat atgtcaaggg atgagctagc caacaagatt ggttgttcag
    11341 ttcatgctat agctaaatat gagcaaaatc aaagaatgcc tagtctagat atgataagaa
    11401 aaatagctac tgctttatca attgctataa ataaactcat tgttgaagaa aatgatttag
    11461 atactttaac aaataataat attaatttaa aagtatttaa taaagagttt gatttagtaa
    11521 ttcacatatt agaaaattat gattatgata taaaaacaga ctataaaaca aagtttgaaa
    11581 ttacagataa tgtagataca ataaaaccaa ttaacctaaa cttctctgat ttcaaaaact
    11641 tctctaaaaa tctaaattgg gtgataaatg gtcttgttga aaattttata caagaaaatt
    11701 ctaatggtct tattgaaaat gaagatgagg aatattagta ctatgcattt tcacaatata
    11761 aatttaattg ttaattttga catagtcata attagataag aattaaataa ggaaggagct
    11821 acaatcatga ataaatcata tataccaaaa tacacatata aattccctac taatctacct
    11881 catggagata aaaaatatac tttaacatac attagaagaa tgataagtga atttgtatat
    11941 gatatgggta aactagaaaa taaccccttt acattcccag aagtacaaac attacttgat
    12001 ggtataacag taggtggaca taaattaagt gatcaaaatc aaatactaaa tataaaatca
    12061 tcatgggatt atgtaataaa attaagtaac aaagaaaact tatctttaaa taaagataca
    12121 atttgctcta tacataaaat agttgcaaaa gatgaagctc taatcgttgg agatttcaga
    12181 aatggtaata taggtatagc tggtactact caatatgaat gcatagaagc cactctatta
    12241 aatgatttat ttgtaaatga cataaatatc ataaataaaa taactaaccc attagaaaag
    12301 gctataataa taaatttatg gttgtcctat tgccaattct tctatgatgg caacaaaaga
    12361 actgctagac ttacctcaaa cctaatactt ataagtaatg atataggagt tctatcaata
    12421 ccagctaaac ataaacaaga atacaacaca ttaatgctaa acttctatga aacactagaa
    12481 gctgatgaag ttataaaatt cttattagag aaatgtatta cattctttga tggatataaa
    12541 tataaatcat ataaggagct gtttaaaaat ggcaactaaa agagctaatg gggaaggctc
    12601 tatcggaaaa tataaagatg gttggcgttc ccgtataatg attggttaca atgaagatgg
    12661 gaaaccaata agaaaagaat tttatggtaa gactcaaaaa gaagttaaag ataaattaga
    12721 tgcttataaa aaacaatatt atttaagctc tgatatttca gatgataaaa taactttaga
    12781 gcattggttt tacaattggt tatttgaata tagaataaaa gatttaaaac ctaagtcatt
    12841 tgagagatat gaaagcatct atcgaaatta tattaaagat actgatttag gcaatgtgaa
    12901 attaaaagac ttaagagtat ctcacataca aaaatattac aatagattgc ttgattccaa
    12961 taaaagtata cctactataa ggcaaataaa cactaaattg aaaacctgct tatcagaagc
    13021 tgaaaaacaa ggtcttatac aacgtaatta ttgtactatg gtaaatatac cagttgagaa
    13081 aaaggaaaat aagcttgaaa tattgactct tgaacaacaa aagagtttta taaaagctat
    13141 agatgggcat aaattagagg tattattttt acttgctctt ggtactggac ttagattagg
    13201 agaattatta ggacttaaat ggtttgatat tgattttaaa aagtctaatt taacagttaa
    13261 aagaactctt caaagaacat attttataga taaaactgga aatagagagc ttaaagtatt
    13321 agagcaaggg ccaaagacat caaattctta cagaactgta cctattccaa aagatgtttt
    13381 aaataaattg aaagagcata aagtaaatca aaatacagat atattaaagg ctggagaatt
    13441 atatataaat aataattatg tattttgcaa tgaattaggc atccctatag atgataaaag
    13501 acctttaagg aatttaaggt ctatattaaa tagcttaaat atagagccta taaagtttca
    13561 tggtcttaga aaaacttatg caactagact ttttgagaat gatttccctc ctaaaactgt
    13621 acaagtttta atgggtcatt atgatatatc aataacttta aatatatata ctcaagttat
    13681 ggaagataag aaagttgaag ctgtagaaaa gttggataaa atattttcat tgtaaaaatc
    13741 aaatacatat aaatattgtg atttcatata gttaattaca aaatcaaaat aaggatacaa
    13801 attaatttta tattatattg tatccttatt tcgtatctag ttttaattat ttatcttgga
    13861 tagcccttat ggtacattaa tccattttct aacattaatt cttgagccaa gtatatatga
    13921 cccttacagt gcatatctga tacaccctca cttataagtt tatatgtttc agaagtatat
    13981 aaataatcca tactttcttc caagctctta cctgtttgtt tggaaaattc taatatgatt
    14041 tttttatata gtatttgtaa taatgtttta tttgcttcca taatcactat acctcctctt
    14101 cacatctaaa ctttaaatat ttatctatta cattttgatt ggttatacat atttgttcat
    14161 ttggtttata gtattttaat ctttttaaag cttcatcttt ttcaataaga ttatcttgat
    14221 acagttctat tgtattgtaa atcttatcat cagcaatacc acctattata atgtcatatt
    14281 tcatatatat atcactcata tttctacatt ctattataaa atcaagccat tctaaattat
    14341 aactattgaa gatttttacc ttgcagtttt cttttaattt atcaatatct aaagaataac
    14401 tatttaaata tgctttttta cctctttttt taaaacgctc tgtccagtta attgcttgta
    14461 tctttatact ggttacatag aatccttttc caaaatctaa agaatctctt gaaaaggtaa
    14521 tactaggagt ctttaccaca caatatgaac catgatatac aatcattata tcacaccctt
    14581 ttctttaagt acttgcatta aatcttccac tatgtaacct ttactttgag aatgtagtgc
    14641 ttcatagcaa ggtattatat agttatctaa aatatcagta tcatgtttaa gaagtttata
    14701 aactccttct gaatctatat tcaatttttc tgctaaagct tcaatgcaaa aaatagaaaa
    14761 ttctagtttt ctttcatcca ttacaaacct caactcctat caagcttata taatatatat
    14821 ttttactaat taacaactta aactgtctta catttataaa aatattatat cataaagtag
    14881 atattaaaat tctatgttac ctattatcat aataaacaaa taaaataata aacaaataaa
    14941 ataataaaca aataaaataa taaacaaata aaaacttttt atacagccta aatgcacccc
    15001 aatatacccc ccaaaaaacc tctttttctg tggttggggt acggttggtg gattttttca
    15061 ccaaaataaa aaatactaat caataaagac tagtattttc aagtatttca tcattctttt
    15121 ttcaaaattg gtggagacga ggggagtcga acccctgtcc gcaaatcttt tccttgctgc
    15181 atctacatgc ttagccaact tcactaatat ctcacctcac atagcgccaa gtggcaggct
    15241 ctatgcttag ccagtcccaa ttaatctact tcaggtcgag acacccctaa agtagttccc
    15301 tgcataatga cgtccagtct tagtcggcag gaggactaag agggacgagc agcaactagg
    15361 ctgctatcgc gaaattatcg tctgcgttta ttttaaagtt ccccagtttt tacgtgaccc
    15421 agagtaacac gacatgcagc ctcaagttcc aaacccacgt cgaaaccttt acgccccctt
    15481 gagtagttta tagtccagta gacttttctc aaactttatc accattttta ttaaattttt
    15541 aatgtatata taatataata cttttaagaa taaaaatcaa tgttatgttc tagataataa
    15601 agaattttat tctaaaaaat acagttttat ctagtttaat acttacctgt catttctctt
    15661 tctatacgtc tttgtgcatc tttcttagcc atatcttgac gtttatcata tagtttttta
    15721 ccttttgcta aggcaatctc tactttaact ttaccgtttt ttagatacaa actaagtggt
    15781 ataagtgaat acccctttat agtagttgct ccaataagct ttcttatttc atgcttatga
    15841 agtaatagtt ttctaactct taaagaatca acattgaata tatttccttg ctcatatgga
    15901 cttatatgaa cttgttttaa aaatacttcg ctattatcta cagatgcaaa tccatcactt
    15961 aggttaactt tgccttgtct tattgatttt acttctgttc cttttaattc aattccacat
    16021 tcataagttt cttctataaa atattcatgt cttgctcttt tgtttgttgc taatattttt
    16081 ttaccagcca tataaatctc accttctttg ctagaaattt cttccataaa tattagaaat
    16141 ttactaaata tttaatgttg ccaaattatt tgactaactt gtatgataac atatttaggc
    16201 attttagtca atatttcact gatatattaa gttagttagg ctatatataa ttaagtaata
    16261 taaatgtatg aaaatagcta aaaaactact tcgaatatac ttaatactaa actaactcta
    16321 accagtaata ctaatttata aatttcaaaa caaaaatatt acatattata
//
LOCUS       DAEORM030000072        16282 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.074, whole genome shotgun sequence.
ACCESSION   DAEORM030000072 DAEORM030000000
VERSION     DAEORM030000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 16282)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16282)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 16282)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16282
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.074"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            <1..537
                     /locus_tag="KRH23_003259"
     CDS             <1..537
                     /locus_tag="KRH23_003259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsid protein"
                     /protein_id="HHS5226532.1"
                     /translation="CISKIYADWTALGNTADTTVLTTANVLEVFDKLMEKMTEARVPE
                     NGRILYVTPVVNTLIKNAKEIQRTVNIKDGGTSLNRQTTDIDTVKIIKVPSNLMKTAY
                     DFTTGWKVGVGAKQIFMSLVHPSAIITPVSYQFSKLDEPTAVTEGKYFYFEESFEDVF
                     ILNKKADAIQFVVEGAGV"
     gene            537..770
                     /locus_tag="KRH23_003260"
     CDS             537..770
                     /locus_tag="KRH23_003260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226533.1"
                     /translation="MAQVRKLNRILTIEECKIDDFLEMGYDLIDETGKAVKYGKSLNV
                     KDLIAENNILRSKVESLEEENKQLKEKNKLTKK"
     gene            780..1181
                     /locus_tag="KRH23_003261"
     CDS             780..1181
                     /locus_tag="KRH23_003261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226534.1"
                     /translation="MENNLIDEIEKRLESFGYILKDGDKWLIDFIREKIENIIKLDCN
                     IKTMPIELKEIEVDMIVGEFLFTKKNMGQLDIESINFEAVEKSISEGDTKVDFAIGSG
                     SQTPEQRFDSLVAYLTTYGKNKILTFRCLRW"
     gene            1175..1537
                     /locus_tag="KRH23_003262"
     CDS             1175..1537
                     /locus_tag="KRH23_003262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226535.1"
                     /translation="MVSKTRKVIEMLYRDKCTIVEYQPIKDPVTKRTNNKEVVVLENQ
                     PCKLSYKNITSTEQGEVAKLTQTIKLFISPNISVKAGSKLIITNQNNITKEYIRSGEP
                     AIYPKHQEIILELLEDKA"
     gene            1537..1962
                     /locus_tag="KRH23_003263"
     CDS             1537..1962
                     /locus_tag="KRH23_003263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HHS5226536.1"
                     /translation="MARWGSVDFREFKRVCKKMEELTKIDLDKFCKDAARELAARLLG
                     KVIRRTPVDTGFLRQGWNGVAYARSLPVYKQGNNYIIEVVNPTTYASYVEYGHRTKDG
                     KGWVKGQHFLTISEMELQSQVDKIIEKKLLILLKGVFDA"
     gene            1955..2392
                     /locus_tag="KRH23_003264"
     CDS             1955..2392
                     /locus_tag="KRH23_003264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail terminator family protein"
                     /protein_id="HHS5226537.1"
                     /translation="MLNNIIDGISIKLDKTFGESYTIYSEDVEQGINEPCFFIVPLNP
                     SKVSYPSGRTLKKNSFDVHYFPKSNDKSFEINEIAEMLLEELEYIEIDGDLVRGTNMN
                     FEIIDNVLHFFVDYNYFTIKSNDTDKMDTVELFGGLKRGDNFE"
     gene            2376..2561
                     /locus_tag="KRH23_003265"
     CDS             2376..2561
                     /locus_tag="KRH23_003265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226538.1"
                     /translation="MIILSKTLSKEDNYKFTKEQIVNSKKYVNRKDLLNAILKENDLY
                     SFSEVEDRINKFMKGVS"
     gene            2562..3872
                     /locus_tag="KRH23_003266"
     CDS             2562..3872
                     /locus_tag="KRH23_003266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail sheath family protein"
                     /protein_id="HHS5226539.1"
                     /translation="MALGGGTFVTQNKVLPGAYINFVSATRATSSLSDRGIVAIPLEL
                     DWGIDEDVFQVTSDDFEKYSVKYFGYDYTHEKLKGLRDLFKNIRLGYFYKLNKGVKAS
                     CTIATAKYSGIRGNDLKVTVTTNIDDNAKFDVVTLLDNKKVDTQIAKVITDLQDNDYI
                     TWKKDATLEASAGLVFTGGTNGEAVTGAEYQAFLDKIESYSFNALGCLATTTEIKSLF
                     VEFTKRMRDKVGAKFQTVLYKKSDADYEGVVSVENKIKDIGLVESSLIYWAAGAIAGC
                     DINKSNTNKKYDGEFDVDVNYTQIQLEEALKTGKFIFHKVGDEVHVLEDINTFVSFTD
                     DKNDDFSSNQSVRVLDQIANDIATLFNEKYLGKVPNDKAGRISFWNDVVKHHKELENI
                     RAIEDFKTDDVSVKLGNDKKTVIVSDAVKVINAMSKLYMTVSVS"
     gene            3889..4359
                     /locus_tag="KRH23_003267"
     CDS             3889..4359
                     /locus_tag="KRH23_003267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tube protein"
                     /protein_id="HHS5226540.1"
                     /translation="MAQTINAKDTVSAKKAECFITIEGKRYNFMQAIDLEAKMEKNKS
                     EVPILGRTTKGNKTTGSTNTGSATFHYNTSIFRELLYRYKETGEDIYFDIQVTNEDPT
                     SAVGRQTVVLKDCNMDSGIITKFDADGEYLDEDMDFTFEDWELVEKFNLLAGME"
     gene            4431..4871
                     /locus_tag="KRH23_003268"
     CDS             4431..4871
                     /locus_tag="KRH23_003268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail assembly chaperone"
                     /protein_id="HHS5226541.1"
                     /translation="MSNLSAFLSQNAIKVDNVKYVASNRFLDKEGKPVEWELKVLSSE
                     EDEALRRKCTKRVKVIGNNGKHTGQYTSEIDYNSYVAELCVASTVFPDLKDAELQNSY
                     GVMGEAQLLKTMLTAGEYVNYTVKVNEVNGFDTSFEDKVEEAKN"
     gene            5212..5373
                     /locus_tag="KRH23_003269"
     CDS             5212..5373
                     /locus_tag="KRH23_003269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA];
                     GO_function: GO:0090729 - toxin activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin"
                     /protein_id="HHS5226542.1"
                     /translation="MNNFLLNVIAGVIASLIFCLICKVFLKVKSHSTRGKSKSGWEFD
                     FKIKFHKFK"
     repeat_region   6109..6664
                     /inference="COORDINATES: alignment:CRISPRCasFinder:4.3.2"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=6109..6137
                     /rpt_unit_seq="gttttagattaactatatggaatgtaaat"
     repeat_region   7266..8083
                     /inference="COORDINATES: alignment:CRISPRCasFinder:4.3.2"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=7266..7294
                     /rpt_unit_seq="gttttagattaactatatggaatgtaaat"
     gene            8310..8498
                     /locus_tag="KRH23_003270"
     CDS             8310..8498
                     /locus_tag="KRH23_003270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226543.1"
                     /translation="MKIITDSSRADYFKQRRQNKKTFSVLLDREKVEKIEEHLKKQNK
                     TKTIWLEEKINEELEKEE"
     gene            8617..9486
                     /locus_tag="KRH23_003271"
     CDS             8617..9486
                     /locus_tag="KRH23_003271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BRO family protein"
                     /protein_id="HHS5226544.1"
                     /translation="MENLIVKEFNGSQIYTFMWKEKSCWIANQIVGLFDYADVSKTIQ
                     DCIKAEDFEIEQEYDVLKGNEFNDFVTTLNVVANNIISNKARSITIFYEDGLYGFLQY
                     TDKPIGVQFRKWLRREVLPSIRQTGAYITNNANPEKLREKASEIEKLQLAYNSTSMLK
                     ELLDGAGFDNKSKLLTAKTLYKKAGIDLPIEINEEEHYFDTKQIASKLKIYSKSNKPA
                     QMAVCEIIKKIDLEDSEVKGVWETNGSWTGTVNKYTKSVIDKVRNWIEENNRPAKIQG
                     EKKNFHVVYKEAM"
     gene            9486..9635
                     /locus_tag="KRH23_003272"
     CDS             9486..9635
                     /locus_tag="KRH23_003272"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226545.1"
                     /translation="MGDNLLNNVCNDEKEYLISYLKTLRQKDEHDFYVFKQIVDKYCK
                     QAKYK"
     gene            9765..10541
                     /locus_tag="KRH23_003273"
     CDS             9765..10541
                     /locus_tag="KRH23_003273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SHOCT domain-containing protein"
                     /protein_id="HHS5226546.1"
                     /translation="MGLFRKSKEPCCICGKEKTDQKIKDGAVCIECLMDYMEYKDKQF
                     TFKDGLPTKSEIQIVLDSKKQNDFLVEKFNVTKEINSFIKFDETNKLIYIETKRKNGK
                     IKKNVYSFENITGFELLEDGETITKGGLGSAIAGGVLFGGTGAIVGSIVGKKKTKKII
                     ENLQIKLTLKTISEPVAYINLINVKTKTNSIGYERAYAEAQEILSILAIILKDIEKKR
                     EEINNNNSNADEILKYKNLLDLGAITEEEFNTKKKELLNL"
     gene            10604..12955
                     /locus_tag="KRH23_003274"
     CDS             10604..12955
                     /locus_tag="KRH23_003274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HHS5226547.1"
                     /translation="MATIQTSIRIFDGMTPAFRHMTNAMNIVLSSFEQLQRTSSNAID
                     ANSIRTAREELARAEAGFDRLEQQIREADGQQRRLNEDINKGASSTDRLVGSAKKLAA
                     TYLGIRTLGGLGNLSDQMTSTNARLSMINDGQQSDGGLNKMIFQSAERSRASYLDTAK
                     IVSRVGMNAGKAFSSTKEIVGFAEQLNKKFVIAGASTEEMNSALLQLTQGLGSGVLRG
                     EELNAVFESAPNIIQSIADYLDVDIGKIRSMASEGMLTADIVKNSLLSAAEQTNAEFE
                     KMPYTLGQIFTSVKNNAVMIFGAIQKKIEDTVSSKGFRTFITDVKDSLYVLGAVGFNV
                     FSGFINLLSSPAFQNFFNVMIVGSSLVVQGLGWIITQALNVANVFAQNWSIIAPVIWG
                     IIAVIAIYKITIISLLAIQTLHTTLTLAQSFATALLNGELMAETRFLLLNKLETLGLS
                     QANALLCVSILKVVAVMALVIAAIFVGVAIFNHFAGTSISATGVVVGAFYFLGTCIYD
                     VFAGAWNIVMAFAEFFVNSFNIVIYNVQMLFYKFQNFVINAMGDVGGSFDNCATALAN
                     AFVSAVNIAIKGINGVIKALNLIPGINIKTIGSLDKVDSFVKQYKDYQKTLKEPVKPQ
                     DWKAPYMDIKNPFDSYKKGYEVGQNLENKLKDTFDISKIAEDAKKKLGLDDLWDKKYG
                     LGDGLGSAGLNSPLSDAAKGAKDTAGNTAKMAKTMDKSQEDLKYLRDIAEQEVINRFT
                     GVNIKIDMNNTNNISKDADVDGIVNVLTEKLNDAMVVSAEGIV"
     gene            12972..13664
                     /locus_tag="KRH23_003275"
     CDS             12972..13664
                     /locus_tag="KRH23_003275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HHS5226548.1"
                     /translation="MAYDFYLDGVQLPIPPPKLEIKVTNKNKTVDLINTGEVNILKKE
                     GLSEISFEAEFTHNKLPFCRGQFRDVQFFLSKLELLKTDCKPFQFIVSRELGNKVLFN
                     TNMKVSLEEYNIVEDAENGSDVKVIIKLKQYRDYSTKKLVLAPPKNETGRPNVKIEPK
                     RVDSVNAPSGKKTYTVKAGDSLWSICQKQLGNGSLYKKVYELNKTMMDKANKGKKVPK
                     YTIYKGQVLKLG"
     gene            13657..15549
                     /locus_tag="KRH23_003276"
     CDS             13657..15549
                     /locus_tag="KRH23_003276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdQ/YqbQ family protein"
                     /protein_id="HHS5226549.1"
                     /translation="MADELVLANDRDVRLVIAHWEDFYEPVVLDGITWEIERRGTPSK
                     LEFTIVMDDILQFCEGNSVRLYYKGIGIFYGYIFQKKRDKENHIKIVAYDQLRYFKNK
                     DTYVYSNKTASELVKMLAKDFNLKYNVIEDTKYKLSRVEENKTLFDMILTALDDTLRE
                     KKEMYTLYDDFGRITLKNVASMKLDTVMNNDVIEDFDYNSSIDSDTYTKIKLVRDNEE
                     SGKRDVYIAQDSTHMRSWGILQMFETVDKNMSEAEIKQKCDILLKLYNKKTKSLSLKN
                     VLGDIRVRAGCLVPVFLDLGDIDLQNYMLVEKVKHTFENNSHFMDLTLVDGDEFASYS
                     SSSYSSGNTNNKDEKKNGPAQSITKKNTGKKVPAIFTAYYPGNNAMEGGKTDCNGKPL
                     DVKSRTVAGPMNREGVKKTWYTDDFLKKHPVFEYGDKVKIILPGTAYDNKVYTVKDNG
                     GRIYVETNGTYHIDILLANASECKKFGRKNGYIIIGGDEEQTYKVEGNNQSNTNNNSK
                     EDKLISIAKSKLGCNYVYGAEGPNTFDCSGFTQWCYKQIGIKIPRTVATQSKAGSAVD
                     LKDRSKWKAGDLLCRVGGGSSNHVVMYIGNNQIIHSPQTGDVVKIESVNSYRKGKAYT
                     HVRRFI"
     gene            15563..15823
                     /locus_tag="KRH23_003277"
     CDS             15563..15823
                     /locus_tag="KRH23_003277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2577 domain-containing protein"
                     /protein_id="HHS5226550.1"
                     /translation="MSQDLLQIIKKAAMDAVETSNPMRVVFGTIESISPLRVKIEQKL
                     SIGEIFLIQTDTFKRYTDKKIGDKLVLIRMQGGQQYLILDRM"
     gene            15828..16247
                     /locus_tag="KRH23_003278"
     CDS             15828..16247
                     /locus_tag="KRH23_003278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2634 domain-containing protein"
                     /protein_id="HHS5226551.1"
                     /translation="MLPSDNLDYDIEDVSIINFDVRQEPSKTFKLNIEKNRVDGICDD
                     VEALKQTIFLILNTERYQHLIYSWNYGVELNDLIGEPISYVIPELERRITEALIQDDR
                     IENIDNFEFQNIKGKVQCRFSVHTKYGNIKAEKVVSV"
BASE COUNT         6488 a         1729 c         3122 g         4943 t
ORIGIN      
        1 tgtatatcta aaatatatgc tgattggacc gcattaggta acacagcaga tacaactgtt
       61 cttacaacag caaacgtatt agaagtattt gataagttaa tggaaaaaat gacagaagct
      121 agagtacctg aaaatggaag aatattgtat gttactccag tagtaaatac acttatcaaa
      181 aatgcaaaag agatacaaag aacagtaaac ataaaagatg gtggaacttc tttaaataga
      241 caaaccacag atattgacac agttaaaata attaaagtac catctaatct aatgaaaact
      301 gcatatgatt ttacaactgg atggaaagta ggagtaggag ctaaacaaat ctttatgtcc
      361 ttagttcacc caagtgcaat aattacacct gtttcttatc agttctctaa gttagacgaa
      421 ccaacagcag ttacagaggg aaaatacttc tactttgaag aaagttttga ggatgtattt
      481 atattaaata aaaaagctga tgcaatacaa tttgttgttg aaggagctgg agtataatgg
      541 cacaagtaag gaaattaaat agaatattaa ctatagaaga gtgtaaaata gatgatttct
      601 tagagatggg atatgatttg atagatgaaa ctggtaaggc agtaaagtat ggcaagtcat
      661 taaatgtaaa agatttaata gctgaaaata atattttaag gtcaaaagtt gagtctttag
      721 aagaagaaaa taagcagctt aaagagaaaa ataagcttac taaaaagtag gtgaaaatta
      781 tggaaaataa tctgattgat gaaatagaaa aaagacttga aagttttgga tatatattaa
      841 aagatggaga taagtggtta atagatttta taagagaaaa aatagaaaat attattaaac
      901 tagattgtaa tataaaaact atgccaattg aattgaaaga aattgaagtt gatatgatag
      961 ttggagagtt cttatttacc aagaaaaata tggggcaatt agatatagaa agcattaact
     1021 ttgaagctgt agaaaagtct atatcagaag gtgatacaaa ggtagatttt gctataggaa
     1081 gtggctctca aacaccagaa caacgctttg atagcttagt agcttatctt actacttatg
     1141 gtaagaataa gatattaacc tttaggtgct taagatggta agtaaaacta gaaaagtaat
     1201 agaaatgtta tatagagata aatgtactat agttgagtat cagccaatta aagaccctgt
     1261 aacaaaacga actaacaata aagaagtagt cgtattagaa aatcaacctt gtaagttatc
     1321 atataagaat attacttcaa cagaacaagg ggaagttgct aaacttacac aaactattaa
     1381 actctttata tctccaaata taagcgttaa agcaggttca aaacttatta taactaatca
     1441 aaataatatt acaaaagaat atataagaag tggagaacct gccatatatc caaaacatca
     1501 agaaatcatc ttagaattac tagaggataa agcgtaatgg ctagatgggg cagtgttgat
     1561 tttagagagt ttaaaagagt ttgtaaaaag atggaggagc ttacaaagat tgatttagat
     1621 aagttttgca aggatgcagc aagagaatta gcagcacgat tacttgggaa agtaattaga
     1681 agaacaccag ttgatacagg attcttacga caaggatgga atggagtggc ttatgctagg
     1741 tcgcttcctg tgtataaaca aggaaataat tatattatag aggttgttaa tccgaccaca
     1801 tatgcaagtt atgttgaata tggccataga actaaagatg gaaaaggttg ggttaaagga
     1861 caacatttct taacaatttc agagatggaa ctacaaagcc aagttgataa gattatagag
     1921 aaaaaactat taatattgct taaaggagta tttgatgctt aataatataa ttgatggaat
     1981 atctattaaa ttagataaaa catttggaga gagttataca atttatagtg aagatgtgga
     2041 gcaaggtata aatgaacctt gtttttttat tgttccttta aatccaagca aagtatccta
     2101 tccaagtggc aggacattaa aaaagaactc ttttgatgta cattattttc ctaaaagtaa
     2161 tgataaatca tttgaaataa atgagatagc tgagatgtta ctggaggaat tagagtatat
     2221 agaaattgat ggagacttag tcagaggtac aaatatgaac tttgaaatta tagataatgt
     2281 tcttcatttc tttgttgatt ataactactt tactataaaa agtaatgaca cagataagat
     2341 ggatacagta gagttattcg gtggtttgaa gagaggtgat aattttgagt aaaacattaa
     2401 gcaaagaaga taactacaag tttactaagg agcagatagt taactctaag aagtatgtaa
     2461 atagaaaaga tttattaaat gcaattttaa aagaaaatga tttatattcc ttctcagagg
     2521 tagaggatag aataaataaa tttatgaaag gagtgagtta gatggcttta ggtggaggaa
     2581 catttgtaac acaaaataag gtcctacctg gtgcatatat aaattttgta agtgctacaa
     2641 gggcaaccag ttcattatcg gatagaggta ttgttgcaat acctttagag ttagattggg
     2701 gcatagatga agacgtattt caagtaacca gtgatgattt tgagaagtat tcagtgaagt
     2761 attttggata tgattatact catgagaagc tgaaaggttt gagagattta ttcaaaaata
     2821 taaggttggg atatttttat aaattaaata aaggcgttaa agccagttgt actatagcca
     2881 cagcaaaata tagtggtatc agaggaaatg acttaaaagt aacagttaca acaaatatag
     2941 atgataatgc taagtttgat gttgtaacac ttttagataa taagaaggta gatactcaaa
     3001 tagcaaaggt tattacagac ttacaagaca atgactatat cacttggaag aaggatgcaa
     3061 cactagaagc aagtgcagga cttgtattta ctggtggaac taatggcgaa gctgtgacag
     3121 gagcagagta ccaagctttc ttggataaaa tagaaagcta tagctttaat gctttaggat
     3181 gtttggctac aacaacagaa attaaaagtt tatttgtaga atttacaaag agaatgagag
     3241 ataaggtagg agctaagttt caaacagtac tatataagaa aagtgatgca gattatgaag
     3301 gtgtagtgtc tgtagaaaat aagattaaag atattggatt agtagaatct agtttaattt
     3361 attgggcggc tggagctata gcaggatgcg atataaataa atctaatact aataaaaagt
     3421 atgatggtga gtttgatgtt gatgttaatt atacacaaat acaacttgaa gaagctttaa
     3481 aaactggtaa atttatattc cacaaggtgg gagatgaagt tcatgtgtta gaggatataa
     3541 atacttttgt atcatttaca gatgataaaa atgacgattt ttcaagtaac caaagtgtta
     3601 gagtacttga ccaaattgct aatgatattg caactttatt taatgaaaag tatttaggta
     3661 aagttccgaa tgataaggca ggaagaataa gtttctggaa tgatgttgtt aaacaccata
     3721 aagaattaga gaatataagg gcaatagaag attttaaaac tgatgatgtt agtgtaaagc
     3781 ttggaaatga taagaaaact gtcatagtat ctgatgctgt taaggttata aatgctatga
     3841 gtaagcttta tatgacagtt tcagttagtt agagagggga gtgataatat ggctcaaaca
     3901 ataaatgcta aagatacagt tagtgcaaag aaagctgaat gttttataac tatagaaggc
     3961 aaaagatata attttatgca agctatagat ttagaggcta aaatggaaaa aaataaaagt
     4021 gaagttccaa ttctaggaag aacaacaaag ggaaataaaa caactgggag tacaaatact
     4081 ggaagtgcaa catttcatta taatacttct atttttagag aattacttta cagatataaa
     4141 gaaactggtg aggatattta ttttgacata caagttacaa atgaagaccc tacatctgct
     4201 gtaggaagac agacagtagt acttaaagat tgtaatatgg acagtggaat aattactaaa
     4261 tttgatgctg atggtgagta tttagatgaa gatatggatt tcacttttga ggattgggaa
     4321 ttagtagaaa aatttaattt attggcagga atggagtaaa atacacattt ataaattata
     4381 tatgtgtatt ttttatatga aaaattaaaa taaaaggaga ttagaataat atgagtaatt
     4441 taagtgcttt tttaagtcaa aatgcaataa aggttgataa tgtaaaatat gtagcgagta
     4501 acagattttt agataaagaa gggaaaccag ttgaatggga attaaaagtt ttatcatctg
     4561 aagaagacga agcactaaga agaaagtgta ctaaaagagt aaaagtgatt ggtaacaatg
     4621 gtaagcatac tggacaatat acaagtgaaa ttgactacaa tagttatgta gctgaattat
     4681 gtgtagcatc tacagtattt ccagatttaa aggatgccga actccaaaat agttatggag
     4741 taatgggaga agctcagtta ttaaagacaa tgcttacagc aggtgagtat gtcaattata
     4801 cagtaaaagt gaatgaagtc aatggatttg atacatcttt tgaggataaa gtagaagaag
     4861 caaaaaacta atcagaggtg gcgattttga tgctagcatc actcattatt gtattcaaaa
     4921 attaaagtgg aagccaagtg aatatatgaa tttagaagtt aatgagagag cgttagcagc
     4981 cgcctcaata cttataaaga tagaggatga agaggaagca atgaaagaag ctgaaagaga
     5041 gagaaagagg ggacgaagaa gatagcaaaa taaaaaaata aatatagaat aggtaaaata
     5101 tgtaataatt atatgttata atatttttag caagaagatg taatctacaa tttatagagt
     5161 ggagttcata ctgggataaa acctacttcc taatgaaagg aggtgggaag tatgaataac
     5221 tttttactta atgtaatagc tggcgttatt gctagtttaa tattttgctt aatttgtaaa
     5281 gtatttctaa aagtaaaaag ccactcaact cgtggcaaga gtaaaagtgg ctgggaattt
     5341 gattttaaaa tcaagttcca taagttcaaa tagattcatt taattatgaa cttcactcta
     5401 ccgcaaaata gattgtagtt cttcttgctt ttattatacc acaaattaga aaaaatattg
     5461 tttatataaa ataaaaaata aaaattttta ttaaaaaatt gaaaacttga ttataaagca
     5521 attaatttat aaaatatata taaataagta ggtatttatt tacttgaatt tcattgttta
     5581 tataaaaaaa atggaaaaat atgtaataat tatatgttat aataattgta gcaaggataa
     5641 taatcgaaag tgcgaagggt gattattttc atattaaacg ccaaattcca aataaggaag
     5701 gaggtgaaat tatatgatag gttttttatt aagcatacta gctggtgtta tatcagctta
     5761 tatttatgac aaaataaaaa atcacccaga cgccaataag ggtgatttaa aaaaataata
     5821 ttttcactta acaactgaaa ataatcactc tttgtaggag taaattattt ccttgctttt
     5881 attataccac aaattggtac agatattcaa aaataatatt tttatgatat aataaaaatg
     5941 tagagatttt gcagtgagcg atatttgtta caaaatatgg cttaacactt gaaatctaag
     6001 atgttgaggg tgtgtgataa atgttatcaa ttgcactact catggttcac tgcaaatttg
     6061 agagagatgc gtatgtgtag gtattggaaa tgccaagttt attttggggt tttagattaa
     6121 ctatatggaa tgtaaattgt tttcttctct ctgttacttc atcttttgta tctagtttta
     6181 gattaactat atggaatgta aataacatag taatatatga ccagacaggt agaataatcg
     6241 ttttagatta actatatgga atgtaaatac aacagcacca tacaaaaacc catttctaaa
     6301 aaacgtttta gattaactat atggaatgta aatatttctg tctttactgc tgtaacgtat
     6361 tggtatgggt tttagattaa ctatatggaa tgtaaatgac tttgaagaaa ataatttagt
     6421 tatatcttgg gaaggtttta gattaactat atggaatgta aattaacctt tttattgttg
     6481 ttgttattct tattgttatt cgttttagat taactatatg gaatgtaaat tttatcattg
     6541 tgtaatgctc tttagtaata gaacctagtt ttagattaac tatatggaat gtaaatttta
     6601 ctgcatttat accatctaca ccttttattt tattgtttta gattaactat atggacttaa
     6661 aattaaaaat actgaaaaac acttactttt atggtaggtg cttttttata ttaaaatctg
     6721 tgtacttaat tgaaatattt ggtaaaatat gtaagaattg tatgatataa taattgtagc
     6781 aaggaaaata ataattgaaa agtgctaaga gtggttattt ccatatttga ataccaaatt
     6841 ccataacgga aggaggtgta acagtatggt gataaatttt ttattgagta tactggctgg
     6901 tgttatatca gccttcatgt atgagaaaat aaaaaaccac tcaaaggcca ataagagtgg
     6961 tttaaaaaag taattcttta aatcaatttt gatggaaata gctactcttg tataaagtaa
     7021 attatttcct tgcttttatt ataccacaaa ttggtacaga tattcaaaaa taatattttt
     7081 acgatataat aaaaatgtag agattttgca gtgttcgatt tttgtaataa aatatggctt
     7141 aacaattgga atacaaggca ttgagggtgt gtgataaatg ttatcaattg cactactcat
     7201 ggttcactgc aaatttgaga gaggtgtgta tgtgtaggta ttggaaatgc taagtttatt
     7261 ttggggtttt agattaacta tatggaatgt aaattgtgat tcctcagctc tctcctttaa
     7321 gctacacaac tgttttagat taactatatg gaatgtaaat taataattat ggagagttag
     7381 gattaggtga tactacgttt tagattaact atatggaatg taaatttaaa agttactaca
     7441 ccagttttag tagttccagc tagttttaga ttaactatat ggaatgtaaa taagatacaa
     7501 gaagaatttt cagtagagga taaattagtt ttagattaac tatatggaat gtaaagccag
     7561 aagaagccgc atctgcaata aagaagtatg gagttttaga ttaactatat ggaatgtaaa
     7621 gattgaaaaa acgtccaaat agcaatataa tttaattagt tttagattaa ctatatggaa
     7681 tgtaaagatt tatgtctgat ttgtgtccaa aaataaccga tttgtgtttt agattaacta
     7741 tgtggtatgt aaagacacct ccaaacactg caatttctcc tgttttcaat agttttagat
     7801 taactatgtg gtatgtaaag cctataggaa gcttaactat atgttcataa aaaacagttt
     7861 tagattaact atgtggtatg taaataatat aacaaagtgg atgttctcta aaaataaaga
     7921 gggttttaga ttaactatat ggaatgtaaa tatttttgat gatttaaaca ttgataaaag
     7981 tatgaaacgt tttagattaa ctatatggaa tgtaaatgat aacaaagctt gcaaagtaga
     8041 tatttgtgtt tttcgtttta gattaactat atggaatgta aattgctgtg atttcactaa
     8101 taaaacaatt aataattgtg ttatagatta actatgtgga gaaaaactaa ataaacaaag
     8161 aaagcactta caaatatgta ggtgcttttg ttttgctcaa attggtcggt tgagtgaaat
     8221 aattagaaaa aattagtaaa aactagtaaa aactcttgaa aagtgtcgcg atacaatgta
     8281 taattatatt atcgcgatac agaaaagagg tgaaaattat tactgatagc agtagagcag
     8341 attacttcaa gcagagacga cagaataaga aaacttttag tgttctacta gatagagaga
     8401 aagtagaaaa aattgaagaa catttaaaaa agcagaacaa gactaaaact atttggcttg
     8461 aagaaaagat taatgaagag ttagaaaaag aggaataaaa aataagagac gttctccccg
     8521 accaaagatt gaacatccct tattgacgta tattatatac actaactata gtatacgtca
     8581 ttccttaaaa aaattcaatt aaggagtgta atagttatgg aaaatttaat agtaaaagag
     8641 tttaatggaa gtcaaattta tacttttatg tggaaagaaa aatcttgttg gatagctaat
     8701 caaatagttg gattattcga ttatgctgat gtatctaaaa caatacagga ttgcataaaa
     8761 gcagaagact ttgagattga acaagagtat gatgtattga aaggaaatga atttaatgat
     8821 tttgtaacta ctttaaatgt agtcgcaaat aatataatta gtaataaagc tagaagtata
     8881 actatttttt atgaagatgg tttgtatgga tttttacaat acacagataa accaattggt
     8941 gtacagttta gaaaatggct tagacgagaa gttttaccaa gcataagaca aactggtgca
     9001 tacataacta acaatgctaa tcccgaaaaa ctaagagaaa aagcaagtga gattgagaaa
     9061 ttacagttgg cttataacag tacatctatg ctaaaagagt tattagatgg tgcaggcttt
     9121 gacaataaat ccaaactatt aacagctaaa acattatata agaaagcagg aattgattta
     9181 ccaatagaga taaacgaaga agaacattat tttgatacaa agcaaatagc atctaaactg
     9241 aaaatatatt ctaagagtaa taaaccagct cagatggctg tttgtgagat tattaaaaag
     9301 attgatttag aagatagtga agttaaggga gtttgggaaa ctaatggaag ttggactggc
     9361 actgtaaata aatatacaaa gagtgtaata gataaggtca gaaattggat agaggaaaat
     9421 aatagacctg ctaagataca aggtgagaag aagaatttcc atgttgtata taaggaggca
     9481 atgtaatggg agataattta ctaaataatg tatgtaatga tgaaaaagaa tatcttattt
     9541 cttacctaaa aactctaaga caaaaagatg aacatgattt ttatgttttc aaacaaatag
     9601 tagataaata ttgtaaacaa gcaaagtata aataagaaat taattatata aattaaaaac
     9661 acttacttag gtaggtgttt ttttattgaa aggaagtgat tataatgtaa aaattttact
     9721 aatatagtat aataatctta taaaattatg tagggggtaa tattatgggg ttatttagaa
     9781 aatcaaaaga accatgctgt atatgtggaa aagaaaagac agaccaaaaa ataaaggatg
     9841 gtgctgtttg tatagaatgt ctaatggatt atatggagta taaagacaaa caatttactt
     9901 ttaaagatgg attacctaca aaatctgaaa ttcaaatcgt tctagattct aagaaacaga
     9961 atgatttttt agttgaaaaa tttaatgtaa ctaaggaaat taacagtttt ataaagtttg
    10021 atgaaactaa taaactcata tatatagaga ctaaaagaaa aaatgggaaa ataaagaaaa
    10081 atgtttatag ttttgaaaat ataacaggct ttgaattgtt agaagacgga gagactataa
    10141 caaaaggcgg tcttgggagt gctatagcag gaggcgtttt atttggtggt acaggagcta
    10201 ttgttggtag cattgtaggt aagaaaaaga caaaaaagat aatcgaaaat ttacaaataa
    10261 agcttacatt aaaaactatt tcagagcctg tggcatatat aaatttaatt aatgtaaaaa
    10321 caaagacaaa ttctattgga tatgaaagag cgtatgcaga agcgcaagag attttatcta
    10381 ttttagctat aattttaaaa gatatagaaa agaaaagaga agaaattaat aataataact
    10441 ctaatgcaga tgaaatatta aaatataaga atttattaga cttaggagca ataacagaag
    10501 aagaatttaa tactaagaaa aaagaattat taaatttata ataactagac acttacaaaa
    10561 gtaagtgttt ttttatggaa atttatgaaa ggagagtgat aaaatggcaa caatacaaac
    10621 atctattcga attttcgatg gaatgacacc tgcttttaga cacatgacta atgctatgaa
    10681 tattgtatta agttcattcg agcaattaca aagaacatct agcaatgcta tagatgctaa
    10741 tagtattaga acagctagag aagaactagc acgtgcagaa gctgggtttg atagattaga
    10801 acaacaaata agagaagctg atgggcaaca gcgaagactt aatgaggata taaataaggg
    10861 tgcaagttct acagatagat tagttggaag tgcaaagaag ttagcagcaa cttatttagg
    10921 tataagaaca ttaggaggtc taggaaattt aagcgaccag atgacaagta ctaatgcgag
    10981 actgagtatg attaacgatg ggcaacaatc ggatggcgga cttaacaaaa tgatatttca
    11041 atcagctgaa aggtcaagag catcttattt agatactgca aaaatagttt cgcgtgtagg
    11101 tatgaatgca ggtaaagcat ttagcagtac aaaagaaatt gtaggttttg cagagcaatt
    11161 aaacaaaaaa ttcgtaatag caggtgcaag tactgaggaa atgaattcgg cattgttaca
    11221 actaacacaa ggattaggaa gtggtgtgct tagaggtgag gaactaaatg ctgtatttga
    11281 gtcagcacct aacattatcc aatcgattgc cgattattta gacgtggata taggaaaaat
    11341 aaggagcatg gcaagtgaag gaatgttaac agcagacatt gtaaaaaact cattactttc
    11401 agcagcagag cagaccaacg cagaatttga gaagatgcct tatacattag gtcaaatctt
    11461 tactagtgta aaaaataatg cagttatgat atttggagct atacagaaga aaattgagga
    11521 tacagtttca agcaagggat ttagaacttt cataactgat gttaaagact cattatacgt
    11581 acttggagca gttggtttta atgtatttag tggatttatt aatttactga gtagtccagc
    11641 ttttcagaat ttttttaatg tgatgattgt tggaagtagt ttagttgtac aagggctagg
    11701 ttggataata acacaagcac ttaatgtagc taatgtattt gcacagaatt ggtcaatcat
    11761 tgctcctgtg atttggggaa tcattgcagt aatagctatt tataaaataa ctattatttc
    11821 tctcttggca atacaaacac tgcatacaac attaacccta gcacaaagct ttgcaacagc
    11881 tttattgaat ggtgaattaa tggcagaaac tagatttttg ttacttaata aattagaaac
    11941 gctaggttta agtcaagcaa atgctttatt gtgtgtaagt attttaaaag ttgttgctgt
    12001 aatggctcta gtaatagcag caatatttgt aggagtagca atattcaatc attttgcagg
    12061 aacaagcatt tctgcaactg gagtagttgt aggagctttt tattttctag gaacttgtat
    12121 atatgatgtc tttgcaggtg catggaatat tgtaatggca tttgcagagt tctttgttaa
    12181 ttcgtttaat attgttatct ataatgtaca gatgttattt tataaattcc aaaactttgt
    12241 aataaatgcc atgggagatg taggaggaag ttttgacaat tgtgctacag ctttagcaaa
    12301 tgcttttgta agtgcagtaa acatagcaat aaaaggtata aatggagtta taaaagcgtt
    12361 aaacttaatt ccaggtataa atataaaaac tataggaagc ttagataaag tagattcttt
    12421 tgtaaaacaa tataaagatt accaaaagac tctaaaagaa cctgtaaagc cacaagactg
    12481 gaaagcacca tatatggaca ttaaaaaccc atttgactct tacaaaaaag gatatgaagt
    12541 gggtcaaaat ttagaaaaca aattaaaaga cacttttgat attagtaaaa tagcagaaga
    12601 tgcaaagaaa aaattaggtc ttgatgattt atgggacaaa aaatatggac ttggtgacgg
    12661 actcggttcg gcagggctta attctccgct cagcgatgca gcaaaaggag caaaagacac
    12721 ggcaggaaac actgcaaaga tggctaaaac aatggataaa agtcaagaag accttaaata
    12781 tcttagagac atagcagaac aggaggtaat aaaccgattt acaggggtaa atataaaaat
    12841 tgatatgaac aatacaaata acataagcaa agatgcagat gtggatggta tagtcaatgt
    12901 tctaactgaa aaattaaatg atgctatggt tgtatcagct gagggaatag tttagaaagg
    12961 agagtgagaa aatggcttat gacttttatt tagatggagt acaattacca atacctccgc
    13021 caaagttaga gattaaagtt acaaataaaa acaagacagt agacctaata aacactggag
    13081 aagtaaatat attaaaaaaa gaaggattat ctgaaataag ttttgaagca gaatttacac
    13141 ataataaatt acctttttgt agaggtcaat ttagagatgt tcaattcttt ttaagtaaac
    13201 tagagttact aaaaactgat tgtaagccat ttcaatttat tgtatctcgt gagttaggta
    13261 acaaggtctt atttaacact aatatgaaag tgtcattaga agaatataac atagtagaag
    13321 atgcagaaaa tggctcagat gttaaagtaa taataaagtt aaaacaatat agagattact
    13381 caactaaaaa gttagttctt gcccctccta aaaatgagac tggtagacct aatgtaaaga
    13441 tagagccaaa acgagttgat tcagtcaatg ccccaagtgg taaaaaaaca tacacagtca
    13501 aggcaggaga ttctctttgg tcaatctgcc agaagcaact tggtaatggt tcattatata
    13561 agaaggtata tgagttaaat aaaacaatga tggataaagc taacaagggt aaaaaagtac
    13621 ctaaatacac aatttacaaa gggcaggtgt taaaacttgg ctgatgaatt agttctggca
    13681 aatgataggg atgtaaggct agttattgca cattgggaag atttctacga accagttgtc
    13741 cttgatggga taacgtggga gattgaaaga cgaggtacac caagtaagct tgaatttaca
    13801 atagttatgg atgatatatt acaattttgt gaaggtaact ctgtaaggct gtattataaa
    13861 ggaataggca tattttatgg atatatattt caaaagaaaa gagataaaga aaatcacatt
    13921 aaaattgttg cttacgacca gctaagatat tttaagaata aagatactta tgtgtatagc
    13981 aataaaacag caagtgaact tgtaaaaatg ttggctaaag attttaattt aaaatacaat
    14041 gtcatagaag atactaagta taaactatct agagtcgaag aaaataaaac actctttgac
    14101 atgatactaa cagcactaga tgatactcta agagagaaaa aagaaatgta taccttgtat
    14161 gatgattttg gaagaataac attaaagaat gttgcatcaa tgaaactgga tactgtcatg
    14221 aacaatgatg tcatagagga ctttgattat aattcaagta tagatagtga tacttataca
    14281 aaaatcaaac ttgtaagaga caacgaggag tcaggaaaaa gagatgtgta tattgctcaa
    14341 gactctacac atatgaggag ttggggaata cttcaaatgt ttgagacagt tgataaaaac
    14401 atgagtgaag cagagataaa acaaaagtgt gatatacttc taaaactata taataagaaa
    14461 actaagtcat taagtttaaa aaatgtactt ggtgatatta gagtgagagc aggttgttta
    14521 gtacctgttt ttttagattt aggagatatt gatttacaaa attatatgtt agttgagaaa
    14581 gtaaagcaca catttgaaaa taattcgcac tttatggatt tgactcttgt tgatggagat
    14641 gaatttgctt cttattcttc aagctcatat agtagtggaa atactaataa taaagatgaa
    14701 aagaaaaatg gtcctgcaca aagtattacg aaaaaaaata caggtaaaaa agttcctgct
    14761 atatttactg catattatcc agggaacaat gcaatggaag gcggaaaaac agattgcaat
    14821 ggaaagccac ttgatgtaaa atcaagaact gttgctggtc caatgaatcg agaaggagtt
    14881 aagaaaactt ggtatactga tgattttcta aagaaacatc cagtttttga atatggagat
    14941 aaagtaaaaa ttatacttcc tggtactgcc tatgacaaca aagtatatac agttaaagat
    15001 aatggaggaa gaatatatgt tgaaacaaac ggaacatatc atatagatat actattagct
    15061 aatgctagtg aatgtaaaaa atttggtaga aagaatggct atataattat aggtggagat
    15121 gaagaacaaa catataaagt tgaaggtaat aaccaaagta atacaaataa caattctaaa
    15181 gaagataaat taattagtat agcaaaaagt aaactgggtt gtaattatgt gtatggagca
    15241 gaaggtccta atacttttga ttgttctgga ttcactcaat ggtgttataa acaaataggt
    15301 ataaaaattc ctaggactgt tgcaacgcaa agtaaggcag gtagtgcagt agatttaaaa
    15361 gatagaagca agtggaaagc aggagactta ttatgtagag ttggtggagg aagtagtaat
    15421 catgttgtaa tgtatattgg aaacaatcaa ataattcatt cgccacaaac tggtgatgta
    15481 gtaaaaatag agtctgttaa ttcttataga aaaggaaaag catacacaca tgtgagaaga
    15541 tttatataag tgaggtggca atatgagcca agatttatta cagataataa aaaaagctgc
    15601 aatggatgca gtagaaacaa gcaacccaat gagggttgta tttggaacaa tagaaagtat
    15661 tagtcctcta agagttaaga tagaacaaaa actatctatt ggtgaaattt ttctaataca
    15721 aacagataca tttaaaagat atacagataa aaaaatagga gataaattag tcttaattcg
    15781 tatgcaagga ggacagcaat atttgatttt agataggatg tgataaggtg ttaccaagcg
    15841 ataatttaga ttatgacatt gaagatgtat cgataattaa ttttgatgtt agacaagaac
    15901 caagtaagac gtttaaattg aatatagaga aaaatagagt agatggtatt tgtgatgatg
    15961 tagaagcatt aaaacaaacc atctttttaa ttttaaacac agagagatac caacatctaa
    16021 tatatagttg gaattatgga gtcgagttga acgaccttat tggagaacct atttcatatg
    16081 taatacccga acttgaaaga aggataacag aagcactaat tcaagatgat aggattgaaa
    16141 atatagataa ttttgagttt caaaatataa agggtaaagt acaatgtaga ttttcagttc
    16201 atacaaaata tggaaatata aaagcagaga aggtggtgag tgtataattg tttgagttaa
    16261 tgacatttga aaatataatt aa
//
LOCUS       DAEORM030000073        15978 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.076, whole genome shotgun sequence.
ACCESSION   DAEORM030000073 DAEORM030000000
VERSION     DAEORM030000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15978)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15978)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 15978)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15978
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.076"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            248..397
                     /gene="rpmG"
                     /locus_tag="KRH23_003279"
     CDS             248..397
                     /gene="rpmG"
                     /locus_tag="KRH23_003279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014262850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HHS5226552.1"
                     /translation="MRVKVTLACTECKQRNYNTTKNKKNNPDRIELQKYCRFCKKHTT
                     HKETK"
     gene            423..644
                     /gene="secE"
                     /locus_tag="KRH23_003280"
     CDS             423..644
                     /gene="secE"
                     /locus_tag="KRH23_003280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HHS5226553.1"
                     /translation="MAAQKNDGAKTKKRFSLFGYLKETKQELKRVTWPTKKELFKNTS
                     IVLTVVISCTILVWGIDTILSGALALLLK"
     gene            664..1206
                     /gene="nusG"
                     /locus_tag="KRH23_003281"
     CDS             664..1206
                     /gene="nusG"
                     /locus_tag="KRH23_003281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0032784 - regulation of DNA-templated
                     transcription elongation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HHS5226554.1"
                     /translation="MSELQEASWYVVHTYSGHENKVKATIEKAVKTRGMEDCIRQVVV
                     PTEEVVETTKTGKEKTRQRKVYPSYVLVKMIITDESWYVVRNTKGVTGFVGPGSKPVP
                     LSEDEVKAMGIDTTDPKVVNSDIDFEIGDTVKVSQGPFSGQIGNIEEIDLENREVKVC
                     INAFGKRTLFVIELEGIEKI"
     gene            1245..1670
                     /gene="rplK"
                     /locus_tag="KRH23_003282"
     CDS             1245..1670
                     /gene="rplK"
                     /locus_tag="KRH23_003282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012158357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HHS5226555.1"
                     /translation="MAKKVIGQIKLQIPAGKATPAPPVGPALGQHGVNIMGFTKEFNA
                     KTADQAGMIIPVVITVYQDRSFSFITKTPPAAVLIKKALNLKSGSGEPNKKKVAKMTS
                     AQVREIAELKMPDLNAASVEAAMSMIAGTARSMGVVIED"
     gene            1741..2439
                     /gene="rplA"
                     /locus_tag="KRH23_003283"
     CDS             1741..2439
                     /gene="rplA"
                     /locus_tag="KRH23_003283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HHS5226556.1"
                     /translation="MAKKGKRYAGALQKVDRTKFYDASEALTLVSDIAGAKFDETVEA
                     HIKLGVDSRHADQQVRGAVVLPHGTGKTKRVLVFAKGEKAKEAEQAGADFVGAEELVQ
                     KIQGENWFDFDIVVATPDMMGVVGRLGRVLGPKGLMPNPKSGTVTFDVAKAIDEIKAG
                     KVEYRLDKTNIIHVPVGKVSFGGEKLTENFTALMDAIIKAKPAAAKGQYLRSITVASS
                     MGPGVKINPARTAE"
     misc_feature    2491..2619
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            2662..3168
                     /gene="rplJ"
                     /locus_tag="KRH23_003284"
     CDS             2662..3168
                     /gene="rplJ"
                     /locus_tag="KRH23_003284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HHS5226557.1"
                     /translation="MRKAIEIKSEVVSEIVEKLQKSSAAVVVDYKGLTVEEVTELRKQ
                     MREAGVDYKVYKNTLVRRAAKEVGIEQFNDELLVGTNAIAFGYDDPVAPARILKGFMD
                     SHPKMKLKMGIVEGAFYDESKIVEMANIPSREVLIAKLLGSLKAPVSNFAYLIDAIAK
                     KAEGQEEA"
     gene            3226..3591
                     /gene="rplL"
                     /locus_tag="KRH23_003285"
     CDS             3226..3591
                     /gene="rplL"
                     /locus_tag="KRH23_003285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002842856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HHS5226558.1"
                     /translation="MTIEQILEAIENMKVLELNELVKAAEEKFGVSASAPVMVAGAAA
                     GGPAAEEKTEFDVVLTDVGSSKVGVIKAVREITGLGLKEAKEVVDNAPKTVKEGASKE
                     EADQIKEKLEAAGAKVEVK"
     gene            3983..4771
                     /gene="hdhA"
                     /locus_tag="KRH23_003286"
     CDS             3983..4771
                     /gene="hdhA"
                     /locus_tag="KRH23_003286"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_process: GO:0016042 - lipid catabolic process [Evidence
                     IEA];
                     GO_process: GO:0030573 - bile acid catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="7alpha-hydroxysteroid dehydrogenase"
                     /protein_id="HHS5226559.1"
                     /translation="MEKLQGKIAVVTAATKGIGLASAEILAKNGATVYLAARSEELAN
                     EVINKISAEGGCAKFVYFNAREEETFTSMIEEVVKKEGKIDILVNNFGSTNPSLDKDL
                     VTGDTDNFFDTVNTNLKSVYLPCKAAIPHMIKNGKGSIVNISSIGSVLPDLSRIAYCV
                     SKAAINSLTQNIATQYAKDNVRCNAVLPGLIATKAALDNMSPEFIKEFLKHVPLNRIG
                     EPDDIAKAVLFYASDDSSFITGDLLEVAGGFGLPTPQFADNILG"
     gene            5242..8958
                     /gene="rpoB"
                     /locus_tag="KRH23_003287"
     CDS             5242..8958
                     /gene="rpoB"
                     /locus_tag="KRH23_003287"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed RNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HHS5226560.1"
                     /translation="MPHPVTIGKRTRMSFSKIKEIADVPNLIEIQVDSYEWFLKEGLK
                     EVFDDISPIEDYTGNLILEFVDYSLDDKPKYDIEECKERDATYCAPLKVKVRLINKET
                     GEIKEQEVFMGDFPLMTERGTFVINGAERVIVSQLVRSPGVYYAEERDKTGKRLISST
                     VIPNRGAWLEYETDSNDVISVRVDRTRKQPVTVLLRALGIGTDAEIIDLLGEDERLSA
                     TLEKDNTKTVEEGLVEIYKKLRPGEPPTVESASSLLNALFFDPKRYDLAKVGRYKFNK
                     KLALCYRIMNKISAEDIINPETGEVFVKAGEKISYDLAKAIQNAGINVVNLLMDDDKK
                     VRVIGNNFVDIKSHIDFDIDDLNIKEKVHYPTLKEILDGYSDEEEIKEAIKSRIKELI
                     PKHILLDDIIASISYEFNIFYNIGNIDDIDHLGNRRIRSVGELLQNQVRIGLSRMERV
                     IKERMTVQDMEAITPQALVNIRPVSAAIKEFFGSSQLSQFMDQTNPLSELTHKRRLSA
                     LGPGGLSRERAGFEVRDVHHSHYGRMCPIETPEGPNIGLINSLGTYAKINEFGFIESP
                     YRKFDKETSTVTDEIHYLTADEEDLFVRAQANEPLTEDGKFVNHRVVCRTVNGAVEMV
                     PESRVDYMDISPKQVVSVATAMIPFLENDDANRALMGANMQRQAVPLVRREAPIIGTG
                     IEYRAAKDSGAVVVARNSGIAERVTADEIIIKREDGNRDRYNLLKFKRSNSGTCINQT
                     PIINKGDQIIKGDVIADGPATDLGEVALGRNCLIAFMTWEGYNYEDAILINERLVKED
                     RLSTIHIEEYECEARDTKLGPEEITRDIPNVGDSAIKNLDDRGIIRIGAEVDSGDILV
                     GKVTPKGETELTAEERLLRAIFGEKAREVRDTSLKVPHGESGIIVDVKVFTRENGDDL
                     SPGVNELVRCYIAKKRKIKVGDKMAGRHGNKGVISRVLPEEDMPFMENGTPLDIILNP
                     QGIPSRMNIGQVLEVHLGLAAKTLGWYVATSVFDGANEYDIMDALEEAGYPRDGKLTL
                     YDGRTGESFDNRITVGYMYYLKLHHLVDEKLHARSTGPYSLVTQQPLGGKAQFGGQRF
                     GEMEVWALEAYGAAHILQEILTVKSDDVVGRVRTYEAIVKGENIPEPGIPESFKVLIK
                     ELQSLCLDVKVLTDEDQEIEVRESVDEDDTIGEFELDVVNHMGEVEESNIIEEIEDDF
                     AENAEDEDIENLEEFTEDDLFEEEIDFDSDDFDM"
     gene            9000..12485
                     /gene="rpoC"
                     /locus_tag="KRH23_003288"
     CDS             9000..12485
                     /gene="rpoC"
                     /locus_tag="KRH23_003288"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed RNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HHS5226561.1"
                     /translation="MFELNNFESIKIALASPEKIRQWSRGEVKKPETINYRTLKPEKD
                     GLFCERIFGPQKDWECHCGKYRRVRYKGVVCDRCGVEVTKSKVRRERMGHIELAAPMS
                     HIWYFKGIPSRMGLLLDMSPRSLEKILYFASYVVVDPGETGLNEKQLLTEKEYRTALE
                     KYGYTFTVGMGAEAVKTLLQNIDLEQQSKDLRAELKDSTGQKKVRTIRRLEVVEAFKK
                     SGNKPEWMILDAIPVIPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLKRLLELGA
                     PDIIVRNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSDMLKGKQGRFRQNLLGK
                     RVDYSGRSVIVVGPELKFYQCGLPKKMALELFKPFVMDKLVKEGYAHNIKSAKSIVEK
                     VKPEVWDVLEDVIKSHPVLLNRAPTLHRLGIQAFEPILVEGKAIKLHPLVCTAYNADF
                     DGDQMAVHVPLSVEAQAEARFLMLSVNNILAPKDGSPITTPSQDMVLGCYYLTIEAQD
                     GAKGTGMVFKDFNELLLAYYNKSVHLHALVKLKVTLEDGRSSLVESTVGRFIFNENIP
                     QDLGFVDRKENPFALEVDFLADKKSLGKIIDKCFRKHGNTETAELLDYIKALGFKYST
                     LGGITVAVDDMSVPEEKKVFIAEAEAKVDKYEKAYRRGLISDEERYEKVIETWTETTD
                     KVTDALMGGLDRLNNIYIMAHSGARGSKNQIRQLAGMRGLMANASGKTVEIPVKSNFR
                     EGLSVLEYFTSSHGARKGLADTAIRTAESGYLTRRLVDVSQDVIVREIDCGTEDTTEI
                     YAIKEGNEVIEEIYDRIVGRYTIDPILNPETGEVIVEADSMIQEDEAETIVALGIEKI
                     RIRTVLNCKTNHGVCSKCYGRNLATGKEVNIGEAVGIIAAQSIGEPGTQLTMRTFHTG
                     GVAGADITQGLPRVEELFEARKPKGLAVITEVSGRVEIDETGKRKEVNVIPEEGETQT
                     YVIPYGSRLKVKQGQMLEAGDPLTQGFINPHDIVRVNGVKGVQEYIVKEVQRVYRLQG
                     VDVNDKHIEVIVRQMLSKVKVEDPGDTDLLPGGYEDVLTFNECNKDAIDKGLRPAVAK
                     RVLLGITKASLATDSFLSAASFQETTRVLTEAAIKGKEDHLIGLKENVILGKLIPAGT
                     GMKKYRNIAVEKIED"
     gene            12774..13196
                     /gene="rpsL"
                     /locus_tag="KRH23_003289"
     CDS             12774..13196
                     /gene="rpsL"
                     /locus_tag="KRH23_003289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012158364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HHS5226562.1"
                     /translation="MPTINQLVRKSRKALEKKSTAPALQKGYNSLNKKVTDASAPQKR
                     GVCTSVKTVTPKKPNSALRKVARVRLTNGIEVSAYIPGEGHNLQEHSVVLIRGGRVKD
                     LPGVRYHILRGTLDTAGVDKRRQSRSKYGAKRPKEAKK"
     gene            13319..13789
                     /gene="rpsG"
                     /locus_tag="KRH23_003290"
     CDS             13319..13789
                     /gene="rpsG"
                     /locus_tag="KRH23_003290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007788527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HHS5226563.1"
                     /translation="MPRKGNIPKREVLPDPMYGSKVVTKLINNLMVDGKKGKSQRIVY
                     DAFAIVAEKTGEEALEVFNKAMDNIMPVLEVKARRVGGANYQVPIEVRPERRQTLGLR
                     WLVKYTRARGEKGMVEKLAKEIMDAANNTGASVKKKEDTHKMAEANKAFAHYRW"
     gene            13838..15904
                     /gene="fusA"
                     /locus_tag="KRH23_003291"
     CDS             13838..15904
                     /gene="fusA"
                     /locus_tag="KRH23_003291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HHS5226564.1"
                     /translation="MARKFPLERTRNIGIMAHIDAGKTTTTERILFYTGQTHKIGETH
                     EGASQMDWMEQEKERGITITSAATTASWKDHRINIIDTPGHVDFTVEVERSLRVLDGS
                     VAVFCAKGGVEPQSENVWRQAETYGVPRIAFVNKMDILGADFYNVVSMMKSRLNSNAV
                     PMQLPIGKEDSFIGIIDLLKMDAVIYKDDLGVEMEETDIPEDMKELAAEWREKLVESV
                     AETDEELMMKYLEGEELTIDELKVAIRKATIACEMNPVFCGTAYRNKGVQLVIDAVLD
                     YLPAPTDIPAIKGILADGEEAERHSSDEEPFSALAFKIMTDPFVGKLAFFRVYSGTLE
                     SGSYVLNATKNKRERIGRILQMHANTREEITKVYAGDIAAAVGLKDTTTGDTLCDPAN
                     PIILESMEFPEPVISVAIEPSSKAAQEKMGIALQKLAEEDPTFTVKTDQETGQTIISG
                     MGELHLEIIVDRLLREFKVEAKVGAPQVAYRETITQPVDVEYKYSKQSGGRGQYGHVK
                     IRVAPQEPGEGYKFTNKTVGGSVPKEYVGPVDMGIQGAMQSGIVAGYPVVDVAVELYD
                     GSYHEVDSSEMAFKMAGSMAFKDAMKKGNAVLLEPYFKVEVVTPEDYMGDVMGDLNSR
                     RGLIQGMEARSGAQVINAFVPLSEMFGYSTDLRSSTQGRATYTMIFDHYEQVPASVAK
                     KIAEGK"
BASE COUNT         6259 a         1987 c         3246 g         4486 t
ORIGIN      
        1 ctttactaaa ctgatggatt aaaaggaata acaaaaagag gggttatgct cctctttttt
       61 taacatagaa atacaaaaac attgacacag cataggattt tgtgataact tatacaaggt
      121 aatgattata ggaagttaat aatatcttga atactgtaga tttttaataa atacatattt
      181 taaagatatt atattcacat atattaacaa tatatattat tgtattacaa agttggaggt
      241 gtatcagatg agagttaaag taactttagc atgtacagag tgtaagcaaa gaaactacaa
      301 cactactaag aataagaaaa acaatccaga cagaatagaa ttacaaaaat attgtagatt
      361 ctgtaaaaag catacaactc ataaagaaac aaaatagttt tttataagga tgtgagtatg
      421 gaatggctgc ccaaaaaaat gacggtgcaa aaactaaaaa aaggtttagt ttgtttggat
      481 acttaaaaga aactaaacaa gaattaaaaa gagttacatg gccgacaaaa aaggaactgt
      541 ttaaaaacac aagtatagtt ttaactgtag ttatttcatg cactatatta gtatggggta
      601 tagacactat attatctggt gcactagcgt tattactaaa atagacgaaa agaggtaagt
      661 taaatgtcag aattacaaga agcaagttgg tatgtagttc atacctattc gggacatgaa
      721 aataaagtta aagctacaat tgagaaagca gttaaaacaa gaggtatgga agactgcata
      781 agacaagtag ttgttccaac agaagaagta gtggaaacta ctaaaactgg aaaagaaaaa
      841 actagacaac gtaaagttta tccaagttat gttttggtta aaatgataat aactgatgaa
      901 tcttggtatg tagtaagaaa tactaaggga gttacaggtt tcgttggacc tggttcaaaa
      961 ccagtgccat taagtgaaga cgaagtcaaa gctatgggga tagacacaac agatcctaaa
     1021 gtagtaaata gcgatattga ttttgaaata ggagatacag taaaagtatc tcaaggacca
     1081 tttagtggac aaataggtaa catagaagaa attgacttag aaaatagaga agtcaaagta
     1141 tgcataaatg catttggtaa aaggactcta tttgtaatag agcttgaagg tatagaaaaa
     1201 atctaatact atattataga aaaatctgag gaggtgcgct caaaatggct aaaaaagtta
     1261 taggtcaaat aaaattacaa atacctgcag gaaaggctac tccagcgcca ccagttggac
     1321 cagcattagg acaacatggt gttaatataa tgggattcac aaaagaattt aatgctaaaa
     1381 ctgcagatca agctggaatg ataataccag ttgttataac tgtatatcaa gatagatcat
     1441 tcagttttat aacaaaaact ccaccagctg cagttttaat taaaaaagca ttaaacttaa
     1501 aatcaggttc tggagaacca aacaagaaaa aagttgctaa aatgacttca gctcaagtaa
     1561 gagaaatagc tgaattaaag atgcctgact taaatgctgc atcagtagaa gctgctatga
     1621 gtatgatagc tggtactgct agaagcatgg gtgttgtaat cgaagactaa ttaaaagata
     1681 cacttttttt tataaagtgg gaggctagaa gccgaaatta accacgagga ggaaaataaa
     1741 atggctaaaa aaggtaaaag atatgcaggt gcattacaaa aagtagatag aactaaattt
     1801 tatgatgcat cagaagcatt aacattagtt tcagatatag ctggagctaa atttgatgag
     1861 acagtagaag cacacattaa attaggtgtt gactcaagac atgctgacca acaagtaaga
     1921 ggtgcagttg tattacctca tggaactggt aaaacaaaaa gagttttagt ttttgctaaa
     1981 ggtgaaaaag ctaaagaagc tgaacaagct ggtgctgact ttgtaggagc tgaagaatta
     2041 gttcaaaaaa tacaaggtga aaactggttt gactttgata tagtagttgc tactccagat
     2101 atgatgggtg tagtaggtag attaggtaga gtattaggac ctaaaggttt aatgccaaac
     2161 cctaaatcag gaacagttac atttgatgta gctaaagcta tagatgaaat aaaagctggt
     2221 aaagttgaat acagattaga caaaactaac ataatacacg ttccagtagg aaaagtatca
     2281 tttggtggag aaaaattaac tgaaaacttt actgcattaa tggatgctat aataaaagct
     2341 aaaccagctg ctgctaaagg acaatattta agaagtataa cagtagcttc ttcaatggga
     2401 cctggagtta aaataaaccc agcaagaaca gctgaataat aaaactgttg acacaggttg
     2461 acaaaaatgt tattatatca cttgtcaatg taaaaaagaa tagatttgcc gtagatagtg
     2521 ggtgcgaaag cttaatatcc cgccgaggtt ttagataaat tgagattact aaagcttttg
     2581 atgtctactt ttggcaacaa aagcttttta taatgttgcg gtaaatacta agcctatttg
     2641 gtgaaggagg tgcacatcta tatgagaaaa gctatagaaa ttaaatcaga agttgtttct
     2701 gagatagttg aaaagttaca aaaatcttct gctgctgttg ttgtagatta caaaggatta
     2761 acagttgaag aagtaactga gttaagaaaa caaatgagag aagctggtgt agattacaaa
     2821 gtatacaaaa atactttagt tagaagagca gctaaagaag ttggtataga gcaatttaat
     2881 gatgaattat tagttggaac taatgccata gcatttggat atgatgatcc agttgctcca
     2941 gctagaatat taaaaggatt catggattct catccaaaaa tgaaattaaa gatgggtatt
     3001 gtggaaggtg cattctatga tgaatctaag attgttgaaa tggctaacat accatcaaga
     3061 gaagttctta tcgctaaatt acttggtagc ttaaaagctc cagtatcaaa cttcgcatac
     3121 ttaatagatg caatagcgaa aaaggcagaa ggtcaagaag aagcttaatt gcttaactaa
     3181 aaaattataa atattaattt gaaataaaat tcggaggtgc taaaaatgac aatagaacaa
     3241 atattagaag ctatagaaaa tatgaaagtt ttagaattaa atgaattagt taaagctgct
     3301 gaagaaaaat tcggtgtatc agcttcagct ccagtaatgg tagctggtgc agctgctggt
     3361 ggaccagctg ctgaagaaaa aactgagttt gatgtagtat taactgacgt tggttcttca
     3421 aaagttggag ttataaaagc agttagagaa ataacaggat taggattaaa agaagctaaa
     3481 gaagtagttg acaatgctcc taagacagtt aaagaaggag cttctaaaga agaagctgat
     3541 caaataaaag agaaattaga agctgctgga gctaaagtag aagttaagta gtttctttaa
     3601 aaagataccc attgggtatc tttttttatt tataaaaaac tataaagaaa gtatttggaa
     3661 ttataaagaa agtattttta taaaataaaa aaaatttata taatagtact aaattaaggg
     3721 tatcatatat gatgtaatgg tattttaatt taacattatt atcaaattaa aatataaaca
     3781 attgttgtaa tgtctatata taaagtatat aattaaacta aaatgtaaaa ttttacattt
     3841 tagtttaaaa aaatacacga gtgttttgta aataaaatgt aataaataat taattaacaa
     3901 atataaattt taaaataagt tagatattta gaaaaatcga aatttgtagg atttaaagga
     3961 catattcaag gaggagttaa taatggaaaa attacaagga aaaattgcag tagttactgc
     4021 agcaacaaaa ggtattggat tagcatcagc agagatatta gcaaaaaatg gagcaactgt
     4081 gtacttagca gctcgttcag aagaattagc taatgaagtt ataaataaaa taagtgcaga
     4141 aggtggttgt gctaagtttg tttactttaa tgctcgtgaa gaagagacct ttacctcaat
     4201 gatagaagag gtagttaaaa aagaaggtaa gatagatata cttgtaaaca attttggttc
     4261 aacaaaccct tctcttgaca aagaccttgt aactggggat acagataatt tctttgacac
     4321 agtaaatact aatttaaaaa gtgtgtattt accatgtaaa gcagcaattc ctcatatgat
     4381 aaagaatgga aaaggaagta tagtaaatat atcaagtata ggttcagtat tacctgattt
     4441 atctagaata gcttactgtg tatcaaaagc agcaatcaac tcattaactc aaaacatagc
     4501 tacacaatat gctaaagaca atgttagatg taatgctgta cttccagggc ttattgcaac
     4561 taaagcagca ttagacaata tgtctccaga gttcataaaa gaatttttaa agcatgttcc
     4621 tttaaatcgt ataggggaac cagatgatat agcaaaagct gttctattct atgctagtga
     4681 tgactcatca tttataacag gggatttact tgaagttgca ggaggatttg gtttacctac
     4741 tccacaattt gcagataata tattaggata attaaattac taatatgcaa tgaaagctta
     4801 tgcattagtt atagtagaaa tgatattttt ataaaggcca tagatataat ttatattgga
     4861 aaggtttgag gttcaaaatt ccaagttaaa tttatttatg gtctttattt tgtatatttt
     4921 aataaattgt atatatttgt ataaatgtaa ttatttacaa tcattttaat atggaattat
     4981 aattaaatag gggggatggt acttgtataa aattttttat agaaagttag acctataaat
     5041 gaaaaatatg gattttatat tggaaaattg tacataatac ataatatatg cttaaaataa
     5101 tttacaaaaa atcaaaaata atgcatagtt tacatataag ataaaaaata tattgaaaaa
     5161 tacttgacat tatgctaaaa ttattagatg cgttagaatg aactattgtt ttatttttaa
     5221 ttattgagag gtgaaaagtg aatgccacat cctgtcacga taggtaaaag aactagaatg
     5281 agcttttcta aaattaagga aatagctgat gtgccaaatc ttatagaaat tcaagtagat
     5341 tcctatgagt ggtttttaaa agaaggttta aaagaagtgt ttgatgatat ttcaccaata
     5401 gaagattata ctggtaatct tatattggaa tttgtcgact attctctaga tgataaacca
     5461 aagtacgata tagaagagtg taaagagaga gatgctacat attgtgcacc tctaaaggtt
     5521 aaggtaagac ttataaataa agaaacaggt gagataaaag aacaagaagt gtttatgggt
     5581 gacttccctt taatgacaga aagaggaact ttcgttataa atggagcaga aagagttata
     5641 gtaagtcaat tagttagatc tcctggtgtt tactatgcgg aagaaagaga taaaacaggt
     5701 aagagattga tttcatctac tgtaattcct aatagaggag catggttaga atatgaaaca
     5761 gattctaatg atgtaatatc tgtaagagtt gatagaacaa gaaaacaacc agttacagtt
     5821 ttacttagag ctttaggaat aggaacagat gcagagataa ttgacctttt aggagaagat
     5881 gagagattat ctgctacatt agaaaaagat aatactaaga cagtagaaga aggtcttgta
     5941 gagatataca aaaaattaag accaggtgaa cctcctactg tagaaagtgc atcatcttta
     6001 ttaaatgctt tattctttga cccaaaaaga tatgacctag caaaagttgg tagatataaa
     6061 ttcaataaga aacttgcttt atgttataga ataatgaata aaatttcagc agaagacata
     6121 ataaatccag aaactggaga agtatttgta aaagctggag aaaaaataag ctatgatttg
     6181 gctaaagcca tacaaaatgc aggtataaat gtagtaaatc tactaatgga tgatgataaa
     6241 aaagttagag ttataggaaa taattttgtg gatattaagt ctcacattga ttttgacata
     6301 gatgatttaa acataaaaga aaaagtacat tatccaactt taaaagaaat tttagatgga
     6361 tatagtgatg aagaagaaat aaaagaggct ataaaatcaa gaattaaaga acttatacca
     6421 aaacatatat tattagatga tataatagct tcaataagtt atgagttcaa tatattctat
     6481 aatataggaa atattgatga tatagatcac ctaggaaaca gaagaataag atctgtaggt
     6541 gaattgttac aaaatcaagt tagaattggt ctttcaagaa tggaaagagt tataaaagaa
     6601 agaatgacgg ttcaagatat ggaagctata acgcctcaag cgttagttaa cataagacca
     6661 gtttcagctg caataaaaga attttttggt agttctcagt tatctcagtt catggatcaa
     6721 acaaatcctc tatctgagtt aacgcataag agaagattat cagcccttgg gcctggaggt
     6781 ctttcaagag aaagagctgg attcgaagtg cgtgacgttc accattcaca ctatggtaga
     6841 atgtgtccaa tagagactcc agagggacca aatatcggtc ttataaactc tctaggaact
     6901 tatgcaaaaa taaatgaatt tggatttata gaatcaccat atagaaaatt tgataaagaa
     6961 acatcaacag ttactgatga aatacattat ttaactgctg acgaagaaga tttattcgta
     7021 agagctcagg caaatgagcc attaacagaa gatggtaaat tcgtaaacca tagagttgtt
     7081 tgtagaactg taaatggtgc tgttgaaatg gttcctgaaa gtagagtaga ttacatggat
     7141 atatctccta agcaggttgt atctgttgcc actgctatga tacctttctt agaaaatgat
     7201 gatgccaacc gtgcccttat gggagcgaac atgcagcgtc aggcagtgcc tctagttaga
     7261 agagaagcac caattatagg aactggtata gaatacagag cagcaaaaga ctctggagca
     7321 gttgttgttg ctagaaattc tggtatagca gaaagagtaa cagcagatga aataattata
     7381 aaaagagaag atggaaacag agatagatat aatctactta agtttaaacg ttcaaactca
     7441 ggtacttgta taaatcaaac acctataata aataagggtg accagataat aaaaggtgat
     7501 gttatagcag atggtccagc aactgattta ggagaagttg cacttggaag aaactgtctt
     7561 atagcattca tgacttggga aggttataac tacgaggatg ctatattaat aaatgaaaga
     7621 ttagttaaag aagatagatt atcaacaatt catatagaag aatatgaatg tgaagctaga
     7681 gatacaaaac tagggccaga ggaaataact agagatatac ctaatgttgg agatagtgca
     7741 attaagaact tagatgacag aggtataata agaataggtg cagaagtaga ctcaggtgat
     7801 atattagttg gtaaagtaac tccaaaagga gaaactgaac ttactgctga ggaaagatta
     7861 cttcgtgcaa tatttggaga aaaggctaga gaagttagag atacttcact taaagtgcct
     7921 catggtgaat ctggtataat agttgatgta aaagtattta ctagagaaaa tggagatgat
     7981 ttatctccag gagtaaatga attagtaaga tgctatatag ctaaaaagag aaaaataaaa
     8041 gttggagata aaatggctgg tcgtcatggt aataaagggg ttatctcaag agtattacct
     8101 gaagaagata tgccattcat ggaaaatgga acaccactag acataatact taacccacaa
     8161 ggtataccat cacgtatgaa cattggtcag gttttagaag ttcatttagg acttgctgct
     8221 aagacattag gatggtatgt agcaacatca gtattcgatg gtgctaatga gtatgacata
     8281 atggatgctc ttgaagaagc tgggtatcct agagatggta aattaacttt atatgatggt
     8341 agaacaggtg agtcttttga caacagaata actgttggat atatgtacta cttgaaacta
     8401 catcacttag tagatgaaaa actacatgca agaagtactg gaccatactc attagttact
     8461 caacagccac taggtggtaa agcacaattt ggtggacaaa gatttggaga gatggaggtt
     8521 tgggctctgg aagcatatgg agctgctcac atacttcaag aaatacttac tgttaagtct
     8581 gatgacgttg taggtcgtgt tagaacatat gaagctatag ttaaaggtga aaatatacct
     8641 gaaccaggaa tcccagaatc atttaaggtt cttataaaag aacttcaaag tttatgctta
     8701 gatgtaaaag tattgacaga tgaagaccaa gaaatagaag taagagaatc tgtggatgaa
     8761 gatgatacaa taggtgaatt tgagctagat gttgtaaatc atatgggaga agttgaagaa
     8821 agtaatataa tagaagaaat tgaagatgat tttgcagaaa atgcagaaga tgaggatata
     8881 gagaatttag aagaattcac tgaagatgat ttatttgaag aagaaataga ttttgatagt
     8941 gatgactttg atatgtaaat ttaattaatg taaatctcaa atagaaggga gagaactcct
     9001 tgtttgaatt aaacaatttc gagtcgataa aaatagcatt ggcttctcca gaaaaaataa
     9061 gacaatggtc taggggagaa gttaaaaagc cagaaactat aaattaccgt actttaaaac
     9121 cagaaaaaga tggtcttttc tgtgaaagaa tatttggacc acaaaaagac tgggagtgcc
     9181 actgtggtaa atatagaaga gttagatata aaggtgtagt ttgtgataga tgtggagtag
     9241 aagtaactaa atcaaaagta agaagagaga gaatgggaca tatagagcta gctgctccta
     9301 tgtctcacat ctggtacttc aaaggtatac caagtagaat gggactttta cttgatatgt
     9361 caccaagatc gttagaaaaa atattatact ttgcctcata tgtagtagtt gatccaggag
     9421 agactggatt aaacgaaaaa caattgctta cagaaaaaga atacagaact gctcttgaaa
     9481 agtatggata tacttttact gtaggaatgg gtgctgaagc tgtaaagaca ttactacaaa
     9541 atatagattt agagcaacaa agtaaagacc taagagcgga gttaaaagat agtacagggc
     9601 aaaagaaagt tagaacaata agaagattag aagttgtaga ggcatttaaa aagtctggaa
     9661 ataaaccaga atggatgatt ttagatgcaa taccagtaat accaccagat ttaagaccaa
     9721 tggtacaact tgatggtgga agatttgcga cttcagacct aaatgattta tatagaagag
     9781 ttataaatag aaacaataga cttaaaagat tattagagct tggagctcca gatataattg
     9841 taagaaatga aaaaagaatg cttcaagaag ctgttgatgc attgatagat aatggtagaa
     9901 gaggtagacc tgtaacagga cctggaaata gaccacttaa atctttatca gatatgttaa
     9961 aaggtaaaca aggtcgtttc cgtcaaaact tacttggtaa gcgtgttgac tactcaggac
    10021 gttctgttat agttgttgga ccagaactta aattttatca atgtggactt ccaaagaaga
    10081 tggcattaga attattcaag ccatttgtta tggataaatt agttaaagaa ggttatgcac
    10141 ataatataaa aagtgcgaaa tctatagtag aaaaagttaa gccagaagtt tgggatgttt
    10201 tagaagatgt tataaaaagt catccagttc ttcttaaccg tgcaccgact ctacatagat
    10261 taggtataca agcatttgaa ccaatcttag ttgaaggtaa ggctataaaa ctacatcctc
    10321 ttgtatgtac agcttataat gcagactttg atggtgacca aatggcagtt catgtacctt
    10381 tatcagtaga agcacaagca gaagcaagat tcttaatgct ttctgtaaat aatatacttg
    10441 ctcctaaaga tggttcacct ataactactc catctcagga tatggtttta ggttgctatt
    10501 atctaacaat agaagcccaa gatggagcta aaggaacagg tatggtattt aaagacttta
    10561 atgaactatt acttgcttat tacaataaat cagttcatct acatgcatta gtgaaactta
    10621 aggtaacact tgaagatgga agaagttcat tggttgaaag tactgttggt agatttatat
    10681 ttaatgaaaa tatacctcaa gacttaggtt ttgtagatag aaaagaaaat ccatttgcac
    10741 ttgaagttga tttcttagca gataaaaaat ctcttggtaa aataatagat aaatgcttta
    10801 gaaaacacgg aaatacagaa acagctgaat tactagatta tataaaagct ctaggattta
    10861 aatattctac attaggtggc ataacagttg ctgttgatga tatgagtgtc ccagaagaaa
    10921 agaaagtatt tatagctgag gcagaagcta aagttgataa gtatgaaaaa gcatacagaa
    10981 gaggtctaat ctctgatgaa gaaagatatg aaaaagttat agagacatgg acagaaacaa
    11041 ctgataaagt tactgatgct cttatgggtg gactagatag attaaataat atatatataa
    11101 tggcacattc aggagccaga ggttctaaaa accaaattag acagctggca ggtatgcgtg
    11161 gtcttatggc aaatgcatct ggtaaaacag ttgagatacc agttaaatct aatttccgtg
    11221 aaggtttatc agtactagaa tactttacat cttcacatgg tgccagaaaa ggtcttgccg
    11281 atacagctat acgtacagct gaatctggat atttaacaag aagacttgtt gatgtaagtc
    11341 aagatgttat tgtaagggaa atagattgtg gaacagaaga tactacagag atttatgcta
    11401 taaaagaagg aaatgaagtt atagaagaga tatatgatag aattgtagga agatatacta
    11461 tagaccctat attaaatcct gaaactggag aagttatagt tgaggctgat tcaatgatac
    11521 aagaagatga agcagaaact atagtagctt taggaattga aaaaattagg ataagaacag
    11581 ttcttaactg taaaactaat catggagttt gttctaagtg ttatggtaga aacttggcaa
    11641 caggaaaaga agttaatata ggtgaagcag ttggtataat agcagctcaa tctatcggtg
    11701 agccgggtac tcagcttaca atgcgtacat tccatactgg aggagttgca ggagctgata
    11761 taactcaagg tctaccaagg gttgaagaat tatttgaagc tagaaaacca aaaggattag
    11821 ctgtaataac tgaagtatct ggtagagttg aaattgatga aacaggaaag agaaaagaag
    11881 taaatgtaat accagaagaa ggcgagactc aaacatatgt aattccatat ggttctagat
    11941 taaaagttaa gcaaggtcaa atgctagagg ctggagaccc tctaacacaa ggatttataa
    12001 atcctcatga tatagtaaga gtaaatggtg ttaagggagt tcaagaatat atagttaaag
    12061 aagttcaaag agtgtataga cttcaagggg ttgatgttaa tgataagcat atagaagtta
    12121 tagtaagaca aatgctatct aaagtaaaag ttgaagaccc aggagataca gatttattgc
    12181 caggtggata tgaagatgta ttaacattca atgaatgtaa taaagatgct atagataaag
    12241 gtctaagacc agcagttgct aaaagagttt tacttggtat aactaaagca tctcttgcaa
    12301 ctgattcatt cttatcagca gcttctttcc aagaaacaac aagagtatta acagaggcag
    12361 caataaaagg taaagaagac cacttaatag gacttaaaga aaatgttata ttaggtaagt
    12421 taataccagc aggaacagga atgaagaaat atagaaatat agctgttgaa aaaattgaag
    12481 attaatagca tatagagtaa agaaatcttg acaaccatta tttgtggtgt taaaatagta
    12541 aagtgtgttg tttaaaagta cactaagggc ttgaacaagt tcttagtgac ttttagatgg
    12601 caataaatga gaactaaaaa gcatcaagct agaaaagtgc taatatcaca tatttatgtg
    12661 ttatagacat taaattgtaa gtaacgaatg ttacaatcag tcagtatgaa tattcatatt
    12721 gatgtagttg gcggtcactg ataagatcga aaatttggaa ggaggtgcag atgatgccaa
    12781 caattaacca attagttcgt aaaagtagaa aagcgctaga gaagaaatct actgctccag
    12841 cattacaaaa aggttacaac tctttaaata agaaagtaac tgacgctagt gccccacaaa
    12901 aaagaggggt ttgtacttca gtaaaaacag ttactcctaa gaagcctaac tcagctttaa
    12961 gaaaagttgc cagagttaga ttaactaatg gtatagaagt ttctgcttat ataccaggag
    13021 aaggacataa cttacaagag catagtgttg ttcttataag aggaggaaga gtaaaagacc
    13081 ttccaggggt tagataccat atactaagag gtactctaga tacagcaggt gttgataaga
    13141 gaagacaatc aagatctaaa tacggtgcga agagacctaa agaagctaaa aaataaaaca
    13201 attaatgatt gattatagtt cggtgcttta aatatatata tatttacggc atcacggcat
    13261 taaatgattt atgtcgagta cctatgattt aagttaaata attaaggagg gaagcgaaat
    13321 gccaagaaaa ggtaatattc caaaaagaga agttttacca gatcctatgt atgggagtaa
    13381 ggtagttact aaattaataa ataatctaat ggtagacgga aaaaaaggaa agtctcaaag
    13441 aatagtttat gatgctttcg caattgttgc tgaaaagaca ggagaagaag ctttagaagt
    13501 atttaataaa gcaatggata atataatgcc tgttttagaa gtaaaagcaa gaagagttgg
    13561 tggggcaaac taccaagtgc caatcgaagt tagacctgaa agaagacaaa cattaggttt
    13621 aagatggcta gtaaaatata ctagagctcg tggagaaaaa ggaatggttg aaaagctagc
    13681 taaagagata atggacgcag ctaacaacac tggagcttca gttaagaaaa aagaagatac
    13741 tcataaaatg gcagaagcta ataaagcatt tgctcattac agatggtagg atatatagat
    13801 atcttataaa attgaggata tcataaggag gataaccatg gctagaaagt ttcctttgga
    13861 aagaactagg aatataggaa tcatggctca tatagatgca ggaaaaacta ctactacaga
    13921 aagaatcctg ttttatactg ggcaaactca taaaatagga gaaactcatg aaggagcttc
    13981 tcaaatggac tggatggagc aagaaaagga aagaggtata acaataactt ctgccgctac
    14041 tactgcttca tggaaagacc atagaataaa cataatagat actcctggac acgtggactt
    14101 cacagttgag gttgaaagat ctctaagagt tcttgacggt tcagttgctg tattctgtgc
    14161 aaaaggtggg gttgagcctc aatcagaaaa tgtatggaga caagctgaaa cttatggagt
    14221 acctagaata gcttttgtaa ataaaatgga tatattaggt gcagatttct acaatgttgt
    14281 aagcatgatg aaatctagat taaattctaa tgcagttcct atgcaattac caataggtaa
    14341 agaagattca tttataggta taatagactt attaaaaatg gatgctgtta tatacaaaga
    14401 cgacctaggg gttgaaatgg aagaaacaga tataccagaa gatatgaaag aattagctgc
    14461 tgagtggaga gaaaaattag ttgaatcagt agctgaaact gatgaagaat taatgatgaa
    14521 ataccttgaa ggtgaagaac ttactataga tgaattaaaa gttgctataa gaaaagctac
    14581 tatagcttgt gaaatgaacc cagttttctg tggtacagct tatagaaaca aaggtgttca
    14641 gttagtaata gatgcagttt tagattactt accagcacca actgatatac cagctataaa
    14701 aggtatatta gcagatggag aagaagctga aagacattct tctgatgaag agccattctc
    14761 tgcattagca ttcaaaataa tgactgaccc attcgttgga aaactagcgt tcttcagagt
    14821 ttattctgga acattagaat caggttctta tgttttaaat gcaactaaga ataagagaga
    14881 aagaattggt cgtatattac aaatgcatgc taatacaaga gaagaaataa ctaaagtgta
    14941 tgctggagat atagcagcag cagtaggatt aaaagatact actactggag acacattatg
    15001 tgaccctgct aatccaataa tacttgaatc tatggaattc cctgagccag ttatatctgt
    15061 tgctatagaa ccaagttcta aagcagctca agaaaaaatg ggtatagctc ttcaaaaatt
    15121 agctgaagaa gacccaactt tcacagttaa gactgaccaa gaaacaggac aaactataat
    15181 atctggtatg ggtgaattac acttagagat aatagtagat agattattaa gagaatttaa
    15241 agtagaagct aaagttggtg caccacaagt tgcatataga gagactataa ctcaaccagt
    15301 tgatgttgaa tacaagtact ctaagcaatc aggtggtaga ggacaatacg gtcacgttaa
    15361 gattagagtt gctcctcaag agccaggtga aggatacaaa ttcacaaaca aaactgttgg
    15421 tggatcagta ccaaaagaat atgttggtcc agttgacatg ggtatacaag gagctatgca
    15481 atctggtata gttgctggat atccagttgt agacgttgct gttgagttat atgatggttc
    15541 ttaccatgag gttgactctt ctgagatggc gtttaagatg gctggttcaa tggcattcaa
    15601 agatgctatg aagaaaggta atgcagttct tttagagcct tacttcaaag tagaagttgt
    15661 tactccagaa gattacatgg gagatgttat gggtgactta aactcaagaa gaggattaat
    15721 ccaaggtatg gaagctagaa gtggtgcaca agttataaat gcattcgttc cactttcaga
    15781 aatgtttgga tactcaacag acctaagatc ttcaactcaa ggtcgtgcaa cttacacaat
    15841 gatattcgat cactatgagc aagttccagc ttcagttgct aagaaaatag ctgaaggaaa
    15901 ataatttaaa aataattaat aatataaata taaaaaataa tcagctagat gagagatatc
    15961 tctcatctag cacaagat
//
LOCUS       DAEORM030000074        15754 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.077, whole genome shotgun sequence.
ACCESSION   DAEORM030000074 DAEORM030000000
VERSION     DAEORM030000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15754)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15754)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 15754)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15754
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.077"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            82..780
                     /locus_tag="KRH23_003292"
     CDS             82..780
                     /locus_tag="KRH23_003292"
                     /EC_number="5.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047661 - amino-acid racemase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate/glutamate racemase family protein"
                     /protein_id="HHS5226565.1"
                     /translation="MNEKLIGILAGMGPRSTAPFVDLIIDECQSQYGAKYDDEFPKMM
                     IYSLPTPFYIDRPINHELMKETIIDGLQKLESIGVNFIAMPCNSAHIYFKELKESINI
                     PILNIVEETVKKLSTISQKVTLFSTSSTFESTIYQNGIIHNGHEFIFKDEWQIKLNNL
                     IQNIKMDKENPHNIDIWNKLIEDVKNESIENIVIACTDLNVVLEKSYPSINIVDSSKC
                     LAESVVNKYLKLVK"
     gene            complement(1025..1642)
                     /locus_tag="KRH23_003293"
     CDS             complement(1025..1642)
                     /locus_tag="KRH23_003293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4878 domain-containing protein"
                     /protein_id="HHS5226566.1"
                     /translation="MKKIILALTTFLLAISLTACSSAKPEDTIDSFFNSAKKFDFEGM
                     NKVMENNDEKYKDILKELDTKDPNAQYVLDYLKQNASKITYTIKDSEVKGDKATIKVE
                     CKFIDSTPLLQEIVAEAFTKMIGMSFSGQDLTDEKTTEMLVSIMKEKQKSVKETYVTK
                     NVEFECSKKDNKWIISSVNDAVADVLLSNLVTAGQEFSNSMNTLE"
     gene            complement(1769..2791)
                     /gene="argF"
                     /locus_tag="KRH23_003294"
     CDS             complement(1769..2791)
                     /gene="argF"
                     /locus_tag="KRH23_003294"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004585 - ornithine carbamoyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0042450 - L-arginine biosynthetic process
                     via ornithine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HHS5226567.1"
                     /translation="MNNISLKGKSFLTLKDFTKEEIRYLLTLSSYLKTKKKVGIKGDL
                     LQGKNIALLFEKTSTRTRCSFEVAAHDEGAHVTYLGPNDCHMGKKESVSDTAKVLGRF
                     YDGIEFRGFKQETVESLAKYSGVPVWNGLTDEYHPTQILADFLTVIENVDKDLNKVKF
                     VYVGDARNNMGNSLMIGCAKMGIHFVALAPKELWPNEELVKEMKEIAKKSKGDIMLTE
                     NIDDVKGADVIYTDVWVSMGEEEQYEARINQLKDYQVNMDMIKKTKNENVIFLHCLPA
                     FHDLETKVAQEIYEKFGLSELEVTNEVFNSKYSKVFEEAENRMHTIKAVMVSTMTDVN
                     MNNNLV"
     gene            complement(2900..4087)
                     /locus_tag="KRH23_003295"
     CDS             complement(2900..4087)
                     /locus_tag="KRH23_003295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008483 - transaminase activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate aminotransferase family protein"
                     /protein_id="HHS5226568.1"
                     /translation="MNNDNTISKWNEYFIDTYNQPNFVIDYGEGSCFFDTNGNKYIDF
                     TSGYGVSSLGYSNSNLKNALKEQVDKLLHTSNLYFNEPVLYSGEKIINSSGMAKVYFC
                     NSGTEANETAFKIARKYSSDKYGNGRGTIISLKDSFHGRTMMSLMATGMDKYHKYFYP
                     LPEGFKYIERNNIEDLKNNLDSTVCAIILEAIQGEGGVNVLEKDYVLEIVKICQEKDI
                     VVIFDEVQCGIGRTGKLFGYEYFDVKPDIVTVAKGLGAGIPVGGVLVNKKLSKVLGKG
                     DQGTTFGGNLLAMVAASVVLDEISKDGFYNEVLEKGNYIRKYIESFNNKVVLKTKGIG
                     LMIGIETNIESSIIEEKARKKGLLILTAGKNVLRFLPPLTISYKEIDEALEILKDILL
                     ESN"
     gene            complement(4117..4977)
                     /gene="argB"
                     /locus_tag="KRH23_003296"
     CDS             complement(4117..4977)
                     /gene="argB"
                     /locus_tag="KRH23_003296"
                     /EC_number="2.7.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003991 - acetylglutamate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006592 - ornithine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetylglutamate kinase"
                     /protein_id="HHS5226569.1"
                     /translation="MINIEKANTLIEALPYIEKHQGKTIVVKYGGSAMKKDGLKESVM
                     EDLVLMSYVGINIVLVHGGGAEINKMLAKVDIESKFVNGLRYTDEETMEIVKMVLAGK
                     VNKDLVNKIHTKGGKAVGLCGIDNNMILCDPYKNYELGFVGEIKKVNVELIESCLKSG
                     YISVIATIGVGDDGETYNINGDTAASAIAKELNADKLILLTDVPGLLREPDEEKSLIT
                     EVILEDVDKLFEEGIITGGMIPKIEGCVDALNNGVNRVHILDGRVPHSIITELFTDSG
                     IGTLIRKENE"
     gene            complement(4992..6209)
                     /gene="argJ"
                     /locus_tag="KRH23_003297"
     CDS             complement(4992..6209)
                     /gene="argJ"
                     /locus_tag="KRH23_003297"
                     /EC_number="2.3.1.1"
                     /EC_number="2.3.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004358 - glutamate N-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006526 - L-arginine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate
                     N-acetyltransferase/amino-acid acetyltransferase ArgJ"
                     /protein_id="HHS5226570.1"
                     /translation="MEIIKGGVTVSEGFFASGIHCGLRKNKEKRDLALVYSDVLCDAA
                     AVVTQNKVKGNPVYVTQEHIKNGKAQAIIVNSANANTFNGKEGLINAYKMAKFTSDKL
                     NIKESDVLVASTGVIGKPLNIDLIEENMDELVNNLSKQGHIGAREAIMTTDIIKKEIA
                     VAIMYGDKKITIGGMAKGSGMIHPNMATTLGFITTDANIDGVLLKEALKIAVDKSFNR
                     VSVDGDTSTNDMVMILANGKAKNDRINKKDEHYQVFLSALTYVCIELAKLVAKDGEGC
                     TKLIECYINGALSEEHAVKLAKTVISSSLVKTAVFGADANWGRILCALGYAGEEIDME
                     KVDIIFESMKGYIEVCKNGNGLDFNEEKAKKILEDDEISILVDLNMGNARGNAWGCDL
                     SYDYVRINGSYRN"
     gene            complement(6250..7284)
                     /gene="argC"
                     /locus_tag="KRH23_003298"
     CDS             complement(6250..7284)
                     /gene="argC"
                     /locus_tag="KRH23_003298"
                     /EC_number="1.2.1.38"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003942 -
                     N-acetyl-gamma-glutamyl-phosphate reductase activity
                     [Evidence IEA];
                     GO_function: GO:0070401 - NADP+ binding [Evidence IEA];
                     GO_process: GO:0006526 - L-arginine biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0006592 - ornithine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyl-gamma-glutamyl-phosphate reductase"
                     /protein_id="HHS5226571.1"
                     /translation="MNKIKVGIIGATGYVGAELIRLLMNHDKVEVTAIGSNSYVGKDI
                     VDIYPSIGYKNNMICIENEKVIDMCDVVFTALPHGVSEKFVIKAIKSKKKVIDLGADF
                     RIKDEEVYSKWYGVSFIDKILHKKAVYGLSEIYKEDIKDADIIANPGCYPTSISLPLM
                     PLLSSKLIKNNNIIIDSKSGLTGAGRELSISSHFTEVNENITAYKIGKHRHTPEIEQN
                     LSESCKEKVSVVFTPNLIPVNRGILSTIYCTKEDNISINDIHRKLTDYYEFKEFIEIL
                     PLDKVASLKNVRFSNKCVISLHENGDTLIICSAIDNMIKGAAGQAIQNMNIIFGIEEN
                     TGLKNIAPSF"
     misc_binding    complement(7538..7751)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(7969..8736)
                     /locus_tag="KRH23_003299"
     CDS             complement(7969..8736)
                     /locus_tag="KRH23_003299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YoaP domain-containing protein"
                     /protein_id="HHS5226572.1"
                     /translation="MQIIDININNIDNEHICCSISEKKGENCVFSKKAWMKNNFDKGL
                     VFKRFDVRGKAFIEYIPAENAWCPITADNYIFINCFWISGKFKGQGYSNLLLQECVDD
                     AKSKGKYGLVVLSSSKKMPFLSDAKYLKYKGFCLADTSEPNYELLYFPFTDNAPIPYF
                     KNCVKKRKLNENGIVLYYSNQCPHTEKYAPILKKIANSRGIDVNLIKFETAKEAQNAP
                     APFTTYSLFFNGEFVTNEILSEKKIEKFLDTNIKKFN"
     gene            9035..9508
                     /locus_tag="KRH23_003300"
     CDS             9035..9508
                     /locus_tag="KRH23_003300"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HHS5226573.1"
                     /translation="MFKEYLIRELKEDDIKNALDLIWNVFEEFESPDYCDEGITTFHQ
                     FIEYNSIIEKIKEKTLFFWGCFDSKKLIGVLAIRNLNHICMLFVDKNYHKHGVAKKLM
                     TTGIQYCICNKFNLTEITVNSSPYAVEVYHELGFKDTAVEQIVDGIRFTPMKLLI"
     gene            complement(9877..10434)
                     /locus_tag="KRH23_003301"
     CDS             complement(9877..10434)
                     /locus_tag="KRH23_003301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HHS5226574.1"
                     /translation="MRVSREIVIQATSDIVNKDGLNKVSLKVIAEKLGIRTPSLYNHI
                     ESLDDLLLEVAHKGMREMNSQMIKAAIGNFGDTAIKCISIAYFNFIISNPGVYETIQW
                     ATWHGNNETLEIFDEYKSLLEKLILSCNLNTKNTGEVLNLIMSVLHGYSTLQLGKSLL
                     SKEEAIKGLVDSIDTVLLGIHKKYD"
     gene            10692..11390
                     /locus_tag="KRH23_003302"
     CDS             10692..11390
                     /locus_tag="KRH23_003302"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HHS5226575.1"
                     /translation="MEKKYFEIHGVPSILWGNPSSKLYIYIHGQCGNKEEAEAFANIA
                     VPHECQVLSVDLPEHGERKREKNSFNPWHVVPELVSIMEYAKCHWNQISLYANSIGAW
                     FSMLSFEKENLRECIFVSPILDMQQLISNMMLWANVSEEQLKHELIIPTSFGHTLSWE
                     YLQYVKQHPITQWNVPTKILYGKHDELTEIGVVEKFVEKFNCNLTVVENGKHWFNTPQ
                     ELNSLYEWLNTLVK"
     gene            complement(11971..12069)
                     /locus_tag="KRH23_003303"
     CDS             complement(11971..12069)
                     /locus_tag="KRH23_003303"
                     /inference="COORDINATES: protein motif:HMM:NF022636.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226576.1"
                     /translation="MFILKRLCKLVSINKSFSEEIPKNLKNTYMCI"
     gene            12413..12880
                     /locus_tag="KRH23_003304"
     CDS             12413..12880
                     /locus_tag="KRH23_003304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HHS5226577.1"
                     /translation="MITKFFSNILSVFLYFLLSLLGVAGIIFLCMIPMFLYDFSSDKV
                     IALIARILYFSDYFIVILFLIFIINSTKYSPFVLENVKRFKVMGFCLLINTIIECING
                     YNLNTNNIRIFGTDSGGISPLMIISFIFALMCFVIAETFDKAIKIKEDNDLTI"
     gene            12891..13106
                     /locus_tag="KRH23_003305"
     CDS             12891..13106
                     /locus_tag="KRH23_003305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHS5226578.1"
                     /translation="MAIVVNLDVMMAKRKISLKELAEKIDITNANLSILKTGKAKAIR
                     FTTLNEICKALDCQPGDILEYVEDEND"
     gene            13547..13720
                     /locus_tag="KRH23_003306"
     CDS             13547..13720
                     /locus_tag="KRH23_003306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinate dehydrogenase"
                     /protein_id="HHS5226579.1"
                     /translation="MKRKLSTYFKGYILGLCIAFLLFTFILKKLIIENIIGIIIGTGI
                     AFLLIYLFNKKRK"
     gene            complement(13877..14161)
                     /locus_tag="KRH23_003307"
     CDS             complement(13877..14161)
                     /locus_tag="KRH23_003307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226580.1"
                     /translation="MLVYNKSFYPNDIFPRLDFSKIKKQLKLIDNDLSDFGSICIIEK
                     EHYTISVNSIGEINVYYDLEYENKVYRIVYEIEKLFKSQVGRFSISTYRN"
     gene            complement(14609..15289)
                     /locus_tag="KRH23_003308"
     CDS             complement(14609..15289)
                     /locus_tag="KRH23_003308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HHS5226581.1"
                     /translation="MQIDVLIIDGDKNSSQELKNFLEGKGINVYLAYNCKDAIIKIFS
                     KKFDLIFLEIILVDGDGWDFCKKIRNITTCPIIHITYINENQSILNALNSGGDDYLIK
                     PLNLEILYAKVKAILRRRDLFLNNNKNNIKLEDYNRASGVIKLENKMIKLTPTENRLL
                     NYFIENAEKTLTIKEIYEHVWMNEYLDDNYSVVVAVSGLRKKIEKDYKNPQKIITIRE
                     VGYYFNKI"
BASE COUNT         5408 a         2466 c         1523 g         6357 t
ORIGIN      
        1 ctattataaa atataatttt atgcttttat agatttttat tttatacata aatatattta
       61 tatataaagg agataatttt tatgaatgaa aaattaattg gtattttggc tggaatgggt
      121 ccaaggtcaa cagccccttt tgttgattta attattgatg agtgtcaatc tcaatatgga
      181 gcaaaatatg atgatgaatt tccaaagatg atgatatatt cattacctac cccattttat
      241 attgaccgtc caataaatca tgaacttatg aaagaaacta taattgatgg attacaaaag
      301 cttgaatcaa ttggtgtaaa ttttattgca atgccatgca attcagcaca tatatacttt
      361 aaagaattaa aagagtctat taatatacca atattaaata ttgtagaaga aacagttaaa
      421 aaattatcta ctatctcaca aaaagtaact cttttttcga ctagttcaac ttttgagtct
      481 acaatttacc agaatggtat aatacataat ggacatgaat ttatatttaa agatgaatgg
      541 caaataaaat taaacaatct tattcaaaat ataaaaatgg ataaagaaaa tccacacaat
      601 attgatattt ggaataaact tatcgaagat gttaaaaatg aatctataga aaatatagta
      661 attgcttgta ctgatttaaa tgtagtttta gaaaaatcat atccttcaat aaatattgtt
      721 gattcatcaa aatgcttggc tgaatcagtt gtcaataaat atctaaaatt agttaaataa
      781 atttttcata cactatatta taaaaaatat atgttataag tttattttaa aatatatgtt
      841 ataagtttat tttaaatagt atagacttat aacatatatc atagtttctt gacaatatag
      901 aaattaacca tgtatttcat tatattaaca aaaaggatac caaaaatggt atccttcata
      961 aatatttata tgtttattta taaaaataat catatattta ttactttact acacctaaac
     1021 aatattattc aagtgtattc atagagttag aaaattcttg tcctgctgta acaagattag
     1081 ataacaatac atcagctact gcatcattta ctgaacttat tatccattta ttatcctttt
     1141 tagaacattc aaactctaca ttttttgtaa cataagtctc tttaacgctt ttttgttttt
     1201 ctttcataat tgatactaac atttcagttg ttttctcatc agttaagtct tgtcctgaaa
     1261 aactcatacc aatcatcttt gtaaatgcct cagctactat ttcttgaagt aatggtgttg
     1321 aatctataaa tttacattct actttgattg tagccttatc acctttaacc tcgctgtctt
     1381 ttattgtata tgtgatttta gatgcattct gttttagata atctaaaaca tattgggcat
     1441 ttgggtcttt tgtatctaat tcctttaata tatccttata tttttcgtca ttattttcca
     1501 ttaccttatt catgccttca aagtcaaact ttttcgcact gttaaaaaaa ctatcaattg
     1561 tatcttctgg ttttgcactt gaacatgctg ttaaagatat tgctaataaa aaagttgtta
     1621 aagctaatat gatttttttc atatctcaaa tcctccctct taatttgttg atacataagt
     1681 tattttaaca tataatgaga gtttttgaat aatatattta aaatatttta taaattttca
     1741 ttaaagtaaa gtctatatta aaacatatct atactaaatt attgttcata tttacatcag
     1801 tcatagtaga aaccataaca gcttttattg tatgcattct attttcagct tcttcaaata
     1861 cctttgaata ttttgaatta aatacctcgt ttgtaacctc taattctgat aatccgaact
     1921 tttcataaat ctcctgagca accttagttt ctaaatcatg aaatgctgga agacagtgta
     1981 aaaatataac attttcattt ttagttttct ttatcatatc catatttact tgataatctt
     2041 taagttgatt tattcttgct tcatattgct cctcttctcc catagaaacc catacatctg
     2101 tatatataac atctgcacct ttaacatcat caatattttc agtcaacatt atatctcctt
     2161 tggatttctt ggctatttcc ttcatttcct taaccaattc ttcatttggc caaagttcct
     2221 taggtgctag tgctacgaaa tgtattccca ttttagcaca tcctatcatc agtgagtttc
     2281 ccatattatt tctagcatca ccaacatata caaatttaac tttattcaaa tctttatcta
     2341 cattttcaat tactgttaaa aaatctgcca gtatttgtgt tggatgatat tcatctgtaa
     2401 gtccattcca aacaggtaca ccagaatatt ttgctagact ttcaactgtt tcttgtttaa
     2461 agcctctaaa ttctattcca tcatagaatc ttcctagaac ttttgctgta tctgatacag
     2521 actctttttt acccatatga caatcatttg gacctagata agttacatgt gctccttcat
     2581 catgagctgc tacttcaaat gaacatctag ttcttgttga tgttttctca aataataaag
     2641 ctatattttt tccttgtagc aaatcgcctt ttataccaac ttttttctta gtttttaaat
     2701 aacttgataa agttaataaa tatctaatct cttcttttgt aaaatccttt aatgtcaaaa
     2761 aactcttacc ttttaaactt atattattca tattaattcg ccccttctta taaacttttt
     2821 aaattcaatt aaacttgtta gcactttact tttttattta cttctaattt ttatctttaa
     2881 tcaactattt tttgaatatt tagttacttt ctaataatat atcttttagg atttcaagag
     2941 cctcatctat ttccttataa ctgattgtta atggtggtaa aaatctcaat acattttttc
     3001 cagcagtcaa aataagcaat cctttttttc tagctttctc ttctataata ctagattcaa
     3061 tattagtttc aattcctatc attagaccaa taccttttgt ctttaataca actttgttat
     3121 taaaactttc aatatatttt cttatataat ttcctttttc taatacttca ttataaaaac
     3181 catctttaga tatctcatct aatacaactg aagctgccac catagctaat aaattacctc
     3241 caaaagttgt accttggtct ccttttccta gtacttttga aagtttttta tttaccaata
     3301 ctcctcctac tggtattcct gctcccaacc cttttgctac ggtaactata tctggtttta
     3361 catcaaaata ttcatagcca aaaagtttac cagttcttcc tataccgcat tggacttcat
     3421 caaaaatcac tacaatatcc ttttcttgac atatttttac tatttccaaa acataatctt
     3481 tttcaagaac attaactcca ccttcgcctt gaatcgcttc aagaattatt gcacaaactg
     3541 tggaatcaag attatttttt aaatcttcaa tattatttct ttctatatat ttaaaacctt
     3601 cgggaagagg ataaaaatac ttatggtatt tgtccatacc agttgccatt aaagacatca
     3661 ttgttctacc atgaaaagag tcttttaaac ttatgatagt tcctctacca ttaccatatt
     3721 tgtcactact atactttctt gctattttga atgctgtttc atttgcttct gttccagaat
     3781 tacaaaaata tactttagcc attccacttg aattaattat tttctctcct gaatacaaca
     3841 ctggctcatt aaaatataaa tttgaagtat gtaataattt atctacttgc tcttttagag
     3901 cattctttaa attactatta ctatacccaa gagaagatac tccatatcca cttgtaaaat
     3961 ctatgtattt attgccatta gtatcaaaaa aacaacttcc ttcaccataa tctatgacaa
     4021 aattgggttg gttatatgta tctataaaat attcattcca ttttgaaatt gtattgtcgt
     4081 tattcattct tattctcccc tcttaaactt ataattttat tcattttctt ttcttattaa
     4141 tgtacctatt ccactatcag taaatagctc tgttattata gaatgtggaa ctcttccatc
     4201 caaaatatgt accctattta ctccgttatt taaggcatct acgcatccct ctattttagg
     4261 tatcatacct ccagtaatta taccttcttc aaataattta tcaacatcct ctaatataac
     4321 ttctgttatt aatgattttt cttcatctgg ctctcttaac aaaccaggga catctgtaag
     4381 aagtatcaat ttatctgcat ttaactcttt agctatagca gaagctgctg tgtcaccatt
     4441 tatattataa gtctctccat catctccaac acctatagtt gcaattactg aaatataacc
     4501 tgactttaga caagattcta taagctcaac atttactttt ttgatttctc ctacaaatcc
     4561 aagttcataa tttttatatg ggtcacataa aatcatatta ttatctattc cacaaagccc
     4621 tactgctttt ccaccttttg tatgtatttt atttactagg tctttattaa cctttccagc
     4681 aagtaccatt tttacaattt ccatggtctc ttcatctgta tatctaagac catttacaaa
     4741 tttactttct atatccactt ttgctagcat cttattaatt tctgcccctc caccatgtac
     4801 taaaactata ttgattccaa cataactcat taacacaagg tcttccataa cagattcttt
     4861 tagaccatct tttttcattg cacttccacc atacttaact acaatagtct ttccctgatg
     4921 tttttctata tatggtaaag cttctataag tgtatttgct ttttctatat taatcattaa
     4981 agtatatcct cctaatttct ataacttcca tttattctta cataatcata gcttaaatca
     5041 catccccatg catttcctct ggcattgccc atatttaaat ctactaatat acttatttcg
     5101 tcatcttcaa ggattttttt tgctttttcc tcattaaaat ctaatccatt tccattttta
     5161 catacttcaa tatatccttt catactctca aaaataatat caactttttc catatctatt
     5221 tcttcacctg cataacctaa agcacacagt attctacccc aatttgcgtc agctccaaat
     5281 acagctgtct ttactaatga agaagatata actgtttttg ctaattttac tgcatgttct
     5341 tcacttaatg ctccatttat atagcattca attagttttg tacatccttc tccatctttt
     5401 gcaacaagtt tagcaagttc tatacagaca tatgtaagtg cactcaaaaa tacttgataa
     5461 tgttcatctt ttttgtttat tctatcattt tttgcttttc catttgctag aatcattacc
     5521 atatcattag tacttgtatc tccatctaca ctaactctat taaaactttt gtcaacagca
     5581 atttttaaag cttcttttag caaaactcca tcaatatttg catctgtagt tataaatcct
     5641 aacgttgttg ccatattagg atgtatcatg ccagaacctt ttgccatacc tccaatagtt
     5701 atttttttat ctccatacat tattgctact gctatttctt tttttataat atcagttgtc
     5761 ataatagctt ctcttgctcc aatatgacct tgtttactta gattattcac taattcatcc
     5821 atattttctt ctattaaatc tatatttaat ggctttccta taacacctgt agatgcaacc
     5881 aaaacatcac tttctttaat atttaattta tcactggtga atttagccat tttataagca
     5941 tttataagtc cttcttttcc attaaaggta ttagcattag cactatttac tatgatagct
     6001 tgtgcctttc catttttaat gtgttcctgt gtaacataaa caggattgcc ctttacttta
     6061 ttttgagtta ctactgctgc tgcatcacat aaaacatctg aataaaccaa agctaaatct
     6121 cttttttctt tattttttct caagccacag tgaatccctg aagcaaaaaa tccttctgaa
     6181 actgtaactc caccctttat aatctccata tttatcctcc taattatatg agtttagtat
     6241 tttttatttc taaaatgatg gtgcaatatt ttttaaacct gtattttctt caataccaaa
     6301 tattatattc atgttttgta tagcttgacc tgctgctccc ttaatcatat tatctatagc
     6361 tgaacagatt atcaatgtat ctccattttc atgtaatgat attacacatt tatttgagaa
     6421 tctaacattc tttaaagaag ctaccttatc taatggaaga atttctataa attctttaaa
     6481 ttcataataa tcagttaatt tcctatgtat atcatttata gaaatattat cttcttttgt
     6541 acaatatata gttgataaga ttcccctatt tactgggatt aagtttggtg taaaaactac
     6601 acttactttt tctttgcagg attcacttaa attttgttct atttctggag tatgtctgtg
     6661 cttccctatt ttatatgcag tgatattttc attaacctcc gtaaagtgac tactaatcga
     6721 taattctcta ccagcacctg taagacctga tttagaatca attattatat tattattttt
     6781 tatcaattta gaacttagta atggcatcaa tggtaaagaa atactagttg gataacatcc
     6841 aggatttgca attatatctg catcttttat atcttctttg tatatttcac ttaatccata
     6901 tacagctttt ttatgtaaga ttttatctat aaaagatact ccataccatt tactatatac
     6961 ttcttcatct tttattctaa agtcagcacc taaatctata actttctttt tcgatttaat
     7021 tgcttttatt acaaactttt cactaactcc atgtggaagg gctgtaaaca caacatcaca
     7081 catatctata actttttcat tttctataca tatcatgtta tttttatatc ctatacttgg
     7141 atatatatca actatatctt ttccaacata cgaatttgaa cctatcgctg tcacttcgac
     7201 tttatcatga ttcattaata atctaatcaa ctctgccccg acatatccag ttgcaccaat
     7261 aataccaact tttattttat tcattttgtt ccctccattt ttatattcaa ataatcttaa
     7321 aatcctatct ttccacttta ctatatgata atcatttgat aatacgtaga ttaaaatact
     7381 ctaattaaaa caaaaaaccc cttagcatta taaatactaa gaggcgattt tccgcggtac
     7441 cactcttatt ggtaaaatta caataatcat taaaactcaa attaaaaagt atctacaaaa
     7501 tgtacattta aaattaaaaa agcctcttgg tcaaagacca agagacgaat atacacccgc
     7561 gttaccactc taattgataa gataatctta cccactctaa tctcttaagg cgagattcac
     7621 caattaccat actattactt ctggtaatct cctccaaagc tctattcaca ataaaattcg
     7681 ttactaggct tccaccattc ccagctctct atcaactagc tttatgctac tctctttttc
     7741 acaggatttc aatttatttt cttattgttt tatatgatag tttatttttt taactttgtc
     7801 aatataattt ttaaattttt agaaatattt tctatatggt taatttccag cattttgtat
     7861 ctaaattgcg atataatttt tatatttcat tcgtcaattt aaaaaacatc caaaatatat
     7921 taaattataa aataatatat tttcaaaata caatatttac atcttttttt agttaaattt
     7981 tttaatgttg gtatctaaaa atttctcaat ctttttctca gaaagtatct cgttggttac
     8041 aaattcacca ttaaaaaaaa gactgtatgt agtaaatggt gcaggagcat tttgtgcttc
     8101 ttttgctgtt tcgaatttta taagatttac atcaatacct ctagaatttg caattttttt
     8161 caaaatagga gcatattttt ccgtatgtgg acactgatta ctgtaatata aaactatacc
     8221 gttctcattt aattttcttt tttttacaca attcttaaaa tatggaatag gagcattatc
     8281 agtaaaagga aaatataata gctcataatt tggttctgat gtatctgcta aacaaaagcc
     8341 cttatatttt agatatttag catcagataa aaaaggcatt tttttactag acgaaagcac
     8401 aactaatcca tatttacctt ttgattttgc atcatcaaca cactcttgta gcaatagatt
     8461 agaatatcct tgacccttaa attttccaga tatccaaaaa cagttaataa atatataatt
     8521 gtccgcagta ataggacacc atgcattttc tgctggaata tattctataa aagctttacc
     8581 tcttacatca aatcgtttaa agactaggcc tttatcaaaa ttatttttca tccaagcttt
     8641 tttagaaaaa acacaatttt ctcctttttt ttcagaaatt gaacaacata tatgttcatt
     8701 gtcaatatta tttatattta tatcaataat ctgcatactt atctcctttt ctaattgcat
     8761 aataattttt aaatatattc tatatatttt tatcttaata ttttgaatac aacaacatca
     8821 tgtcatatat atttttattt tacataatat tattttaaga ttatctgaat tatttaattg
     8881 tatatataat taaatacatt ctatggtcta actacactat aatataaatt atatattatc
     8941 ataatattct aaatttataa aacaaattgt attgaattga atttatttaa gatatataat
     9001 tataattaaa ataataataa aggtgttgtt tataatgttc aaagaatact taataagaga
     9061 attaaaagaa gatgatatta aaaatgcatt agacttaatc tggaacgtat ttgaagaatt
     9121 tgaatctcca gattattgtg atgaaggaat tacgacattt catcaattta tagaatataa
     9181 ctctattatt gaaaaaatca aagaaaaaac tctcttcttt tggggttgtt ttgactctaa
     9241 aaaacttatt ggagtcttag ctattagaaa tttaaatcat atatgtatgt tatttgtaga
     9301 taaaaactat cataaacatg gtgttgcaaa aaaattaatg actacaggca tacaatactg
     9361 tatttgtaat aaatttaatt taactgaaat aactgtaaat tcatcacctt atgctgttga
     9421 agtttatcat gaattaggat ttaaagatac tgctgttgag caaattgttg acggtatacg
     9481 ttttacacct atgaaattgt taatataata aattaaataa aaagcaaagt ctcttaaata
     9541 ttttatagtt actttgcttt taaaccaaga tttaaaataa tactatcttt tttgtttttt
     9601 aataatatac tttaaaatcc ttactaatat gaactataat ttattttttg atatcctttt
     9661 tgattaacat ataaattaat tcaattatta aacataaact atgttgtttc tctttatatc
     9721 tcttctttgt aaacaatatt gggcatttga aaataaatat tcttaaaata tactgttctc
     9781 ctgttgattt ccctttggta caaatgataa aattttattt tacatgctcc gtaatgaagt
     9841 gttcaataaa taagttaaaa taatttattt acctccttaa tcatattttt tatgaatacc
     9901 taataacaca gtatcaatag aatcgactaa accttttata gcttcttctt tactcaaaag
     9961 tgatttccca agttgcaaag tcgaataacc atgaagtaca ctcattatta agtttaatac
    10021 ttcacctgta ttctttgtat ttagattaca agaaagaata agtttttcta ataaggattt
    10081 atattcatca aagatttcta atgtttcatt atttccatgc caagtagccc actgaattgt
    10141 ttcataaaca ccaggattag aaattataaa attaaagtat gctatactta tacactttat
    10201 agctgtatct ccaaaatttc caatagccgc ctttatcatt tgactattca tctctctcat
    10261 tcctttatga gctacttcaa gtaataaatc atctagactt tctatatgat tgtacaaaga
    10321 tggtgtacgt attcctagct tttctgcaat aacttttaaa gaaactttgt taagcccatc
    10381 tttattaact atatctgatg tagcttgtat aactatttct ctactaacac gcatgatttt
    10441 ccctctttca tttaaaatta attactttat tagtttagct aatctaatta gtttcgtcaa
    10501 ttattgtaat ttataaaatt ctttatacta ttataaaatc ttgacagttt aattataatt
    10561 taatataata ctaatcgaat tagttttaat actaatataa ttagtattat attaaattct
    10621 atattacaac attattttat agtttgatta attcaacaat cactaatata tcaaactgaa
    10681 aggagatttt tatggaaaaa aaatatttcg aaattcatgg agttccttca atcctttggg
    10741 gaaatccttc aagtaaatta tatatttaca tacatggaca atgtggcaat aaagaggagg
    10801 ctgaagcttt tgctaatatt gcagttccac atgagtgtca agttttaagt gttgatttgc
    10861 ctgaacatgg agaacgtaaa agagaaaaaa attcatttaa cccatggcat gttgttccag
    10921 aattagtatc tattatggaa tatgcaaagt gccactggaa tcaaatttcg ttatatgcaa
    10981 atagcattgg agcatggttt agtatgttaa gctttgaaaa agagaactta agagagtgta
    11041 tttttgtatc tccaattcta gatatgcaac agctcatttc aaatatgatg ctttgggcaa
    11101 atgtatcaga agaacagctt aaacatgaac taattatccc aacttcattt gggcatactc
    11161 tttcatggga atatctacaa tatgtaaaac aacatcctat cactcaatgg aatgtaccaa
    11221 caaaaatatt atatggtaaa catgatgaac ttactgaaat cggtgttgta gagaaatttg
    11281 tagaaaagtt taattgcaac cttactgttg tagaaaatgg caaacattgg tttaacacac
    11341 cacaagaatt aaattcatta tatgaatggt taaatacttt agttaaataa aaaataatta
    11401 tattattaat atgattaaat tatttataaa tgttatttaa ttaattttat tttagcatta
    11461 ttaaaataac tacataaaga ataaattagt tattattaaa aaaattaaaa gtatatagag
    11521 tattaataat tttttaataa ttagttatta tagaaaaaag agggatataa tattgtctcc
    11581 ctctctttct tctgtaatat tatataattt ttatttatca ctctcaataa attatagtta
    11641 tctacaaaat tcaatcttta atacactatt aatatattgt gatattaata ttacagtatt
    11701 aaataaaatc taataaaatt aactataaaa tatctattat ataaatatcc actcttatgt
    11761 ttgaaatcca tcatatagtt ttatccttct tatcttttat atcaataact ttttttaata
    11821 aaattgacaa aactaaagta aaaaacctta ttgataatga cacaaatgat actataagtt
    11881 ctgatattat agtaattgca tataaataga catcataaca ataatataat attgtcacta
    11941 taaaattaaa tgtaaaaatc tcaaatctaa ctaaatacac atataggtat tttttaagtt
    12001 tttaggtatt tcttctgaaa atgatttatt gattgatacc aatttacata atctttttaa
    12061 tataaacaat gatacaatat atgggacagc acatatgtat atagctactt atattacata
    12121 ttacagttgg catattcgta tttgtaatgc ttataccaat tttaaaatac accatcagta
    12181 ctaatggtat taaaataatc tataataaag ttaaaattat tccaattagt acaatattat
    12241 ttaacatttt acaactcata ttctttttta tataaattta ccaccttata cattcttatt
    12301 tttagtgtat attataatgg ttttatatat tatatcaata atttattatt gaaattcaat
    12361 aaattatata ttataatcaa taatatactt tatataaagg agatgatatt ttatgattac
    12421 aaaatttttt agtaatatat tatcagtatt tctatatttt ctattatcac ttttaggagt
    12481 tgctggtata atattcttat gtatgatacc tatgttttta tatgatttta gttctgacaa
    12541 agtaattgct ttaattgcaa gaatactata tttttctgac tactttatag tcatcttatt
    12601 cttgatattt ataattaata gtactaaata ttccccattc gtacttgaaa atgtaaaaag
    12661 gtttaaagta atgggatttt gtttattgat aaacactata attgaatgta tcaatggtta
    12721 taatttaaat actaataata taagaatttt tggaactgat agtggcggta tctcaccact
    12781 tatgattatc tcttttatat ttgcactaat gtgctttgta attgcagaaa catttgataa
    12841 agctataaaa ataaaagaag ataatgattt aacgatatag aggtgatgtt atggcaatag
    12901 tagttaacct agatgtaatg atggcaaaaa ggaaaatatc acttaaagaa ttggcagaaa
    12961 aaatagatat tacaaatgca aatttatcaa ttttaaaaac tggaaaagca aaagctatta
    13021 gatttaccac tctaaacgaa atttgcaaag ctttagactg tcagccaggt gatatacttg
    13081 aatatgtaga agatgaaaat gattaaaaaa gagtgtttag aaacactctt ttttattata
    13141 ctatatgatt tttattcttt tactatatta ttgacattaa tattaacttt gtttaaagtc
    13201 ataacaaaat atgttctaag aaagaaactg ttcctttatc tatttgttat ccattaccta
    13261 taagaactgt atcacactaa atcatacttt taaattgata attttaccac agattcctat
    13321 atacattctt ttctacctaa tatttattta aactgttagc aaaacatgga actttttcat
    13381 ttacttatac ctccatttat attattgcat agtttatagc tacgtgttat aaattacatt
    13441 attgatgatt ttatctaaca tttgtaatct tttagatact ctttgaagtt acaacactgt
    13501 tatactctaa ttaagtaaac taaatctgat acaagttggt gattatatga aaagaaaact
    13561 ttcaacctat tttaaaggat atattttagg tttatgtata gcatttttat tatttacttt
    13621 tatattaaaa aaattaatta tagaaaatat cattggaata ataattggaa ctggaattgc
    13681 attcttactg atttacctat ttaataaaaa aagaaaataa tattctataa aaaggtcttt
    13741 tagtgaattt acaaaaaatt aataagaata atatatactt agtatttaaa aagggtaaca
    13801 actctctcta gctgttacct catatattta tctatatctt tagtattaag ttttttaatt
    13861 tctacttttt taattatcaa tttctgtatg tagatatact aaaccttcca acttgagatt
    13921 taaataactt ttcaatctca taaactattc tatacacctt attttcgtac tctaaatcat
    13981 aatacacatt tatttcacct atactgttta cacttatcgt ataatgttct ttttctatta
    14041 tacatatgct tccaaaatct gacaggtcat tatctatcaa ttttaactgt ttttttattt
    14101 ttgaaaaatc taatcttgga aatatgtcat taggataaaa acttttatta tatacaagca
    14161 tttcatccac cccttatcat tctatttaca ccattttata ccctaattaa taatgtacta
    14221 atcaattttt ccatattttt caaattactt tatataaaac aaaatacaaa tttatttttt
    14281 aatgctttaa attgtaattt ttaaatgtat attagtaaaa tataagtata ttttcatcca
    14341 caacaataaa aaaataatag ctatataaaa atagctacta tctttttatt aattaatatt
    14401 catttgtttt attattacta cttatattat agttttatat attttactga tgtctataat
    14461 atttcagaca ttttttatat ttattctact gctataattc aattaagtaa attaaatcta
    14521 attttacaaa tatatcgtta gaacaaaaac tcttgtaata tactaacata tttatctatg
    14581 ccctatcatt cattctgttt ataaagcttt atatcttgtt aaagtaatac cctacttctc
    14641 ttatcgttat aattttttga ggatttttat aatctttctc tattttcttt cttaatccac
    14701 tcacagcaac cactacacta taattatcat ctaaatactc attcatccat acatgttcat
    14761 atatctcctt aatagttaga gtcttttcag cattctctat aaagtaattt aataatctat
    14821 tttctgttgg agttaacttt atcattttat tttctaactt tattactcca ctagctctat
    14881 tataatcttc tagttttata ttatttttat tattatttaa aaataaatct cttcttctta
    14941 aaatagcttt cactttcgca tataatattt ctaaatttaa aggctttatt aaataatcat
    15001 ctcctccaga atttaaagca tttaaaatac tttgattttc atttatataa gttatatgaa
    15061 taattgggca agtagttata tttctaattt ttttacaaaa atcccaacca tcaccatcaa
    15121 ctaaaattat ctctaaaaat attaagtcaa atttcttgct aaatattttt ataatagcat
    15181 ctttacaatt atatgctaaa tagacattta tcccctttcc ttctaaaaaa tttttcagct
    15241 cttgagaact attcttatct ccatcaatta tcaatacatc aatttgcatt acaatctctc
    15301 ctaaatatca ttatttttct ataaagaatt ggaaaaatat ttttagtaca ttttctaata
    15361 gcatttttta cccttataag aaattttaaa tactataaat ccattttctt tattatttat
    15421 atatatttat tatctaaact gcacacttca aaattcacat agcatccttg tatctctagt
    15481 aagttatttt aagatataca ctttatttgg tatttcattt gattttttat ttactgtata
    15541 aagataagca tatacaatta tataattcaa agctatattt tttattctca taattatatc
    15601 tttaacaatt taatatagat ataaattaaa atttctatta taaaaataaa tttgataata
    15661 tccacattat tgtctacgag cattaggtta tacattaggc actatatata aaattatttt
    15721 aaccaaagta taaaatttcg attattacac aata
//
LOCUS       DAEORM030000075        15726 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.078, whole genome shotgun sequence.
ACCESSION   DAEORM030000075 DAEORM030000000
VERSION     DAEORM030000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15726)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15726)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 15726)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15726
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.078"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            220..420
                     /locus_tag="KRH23_003309"
     CDS             220..420
                     /locus_tag="KRH23_003309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011723062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HHS5226582.1"
                     /translation="MNNGIVKWFNNEKGFGFISMEGRDDVFAHFSAIQTSGFKSLEEG
                     QQVSFDIVKGARGPQAENITIL"
     gene            1235..1417
                     /locus_tag="KRH23_003310"
     CDS             1235..1417
                     /locus_tag="KRH23_003310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
                     /protein_id="HHS5226583.1"
                     /translation="MFKFYNNATLMFLSGTNIKTISERLGHADIKITMNSYSQFLEEM
                     NREAFENLSKILFIVF"
     gene            1488..2333
                     /locus_tag="KRH23_003311"
     CDS             1488..2333
                     /locus_tag="KRH23_003311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HHS5226584.1"
                     /translation="MNIIKSITLLLTLLIVILMTGCSPRESASEVAKKYIDKMNSGDY
                     ETAYSLLSKDSKKKISIENLEEFQNILVSTKRIISYKIGKEKIIKKYKHDGKEYKNVV
                     KLEETFNIKNLLYKKDDSLKVNRYFVVENNKYKLLLYESFKKEFGINSMDLAQLKLND
                     FGLKYFKEVDLILKKAIAINPTDSKLYYAQACNYMNFDGFPGYSDTTYNALDSINKSL
                     KYLDKNDSDYKKNASNIYNLKGVILMFHKRFDEAQQYLNKALYFNKDNEDPKYNLNTI
                     KKHLN"
     gene            complement(2556..2720)
                     /locus_tag="KRH23_003312"
     CDS             complement(2556..2720)
                     /locus_tag="KRH23_003312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226585.1"
                     /translation="MFGKPKESVRFLDFNDVAEKFGEKKAVAIFDAIAGKKSKEHIIK
                     DIEKLVKNEV"
     gene            complement(3261..3593)
                     /locus_tag="KRH23_003313"
     CDS             complement(3261..3593)
                     /locus_tag="KRH23_003313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051920 - peroxiredoxin activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HHS5226586.1"
                     /translation="MNIREMKEYRGFYNKKLSETDEFFRVFGSLDDKTYSEGAISKKN
                     KELMGLAISILSRCDECICYHIEGCINSGASKDEIIEAIKIGVIGGGSITYPNARFAI
                     KILEEFNI"
     gene            complement(3837..4478)
                     /locus_tag="KRH23_003314"
     CDS             complement(3837..4478)
                     /locus_tag="KRH23_003314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HHS5226587.1"
                     /translation="MKKAINKQFILSTLICFIPFIVSIYFYNRLPNEVAIHFDNYGNP
                     DNYAPKVIAAFGVPLLMLCIHLYTWFRLENEPKKANFSNVIQNLSKWGVAILSVIIQI
                     MMVLYSTGVSLESNFYTGLILGIIVILFGNYLPKCKRNYSVGIILPWTLNDEDNWNKT
                     HHLAGWIWLIGGILLIINAFINIPFYNIFVIFVIVILPFIYSYLMYKISGKNN"
     gene            complement(4459..4758)
                     /locus_tag="KRH23_003315"
     CDS             complement(4459..4758)
                     /locus_tag="KRH23_003315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="autorepressor SdpR family transcription factor"
                     /protein_id="HHS5226588.1"
                     /translation="MVLGFPETFKALSDPIRREILVMLRENKMSAGEISEKFNMTNAT
                     ISYHLSQLKKAGLIFETKYKNFIFYEINISVFEEVMLWFSQFMEKGEKDNEKSDK"
     gene            5131..5202
                     /locus_tag="KRH23_003316"
                     /pseudo
     CDS             5131..5202
                     /locus_tag="KRH23_003316"
                     /inference="COORDINATES: protein motif:HMM:NF024729.6"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(5373..5507)
                     /locus_tag="KRH23_003317"
     CDS             complement(5373..5507)
                     /locus_tag="KRH23_003317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226589.1"
                     /translation="MNISRRAMKIIELAQKIANKRGVTVQDAWNDAMKEYKEKYEYVA
                     "
     gene            complement(5718..6470)
                     /locus_tag="KRH23_003318"
     CDS             complement(5718..6470)
                     /locus_tag="KRH23_003318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HHS5226590.1"
                     /translation="MFSVIFLCIGGFLAAFVDSIAGGGGLISMPVLMAIGVPVHLAIG
                     TNKFAASAGCISSAYRYSKSGKINNDLLKKLVPFTIIGSVLGVRCVLSISEEILNVLV
                     VVMILIVAIYTFISKNLGQEDNFEAVNKKNLRLGMLMALIMGFYDGFFGPGTGTFLTF
                     GFIKIYGYDFLHASANTKILNLTSNITSLLLFMINGQVDYKIAIVFALVMIMGAYVGA
                     KVAIKKGSKMIKPIFLVMALFMVVKLVYQTLV"
     gene            complement(6529..8184)
                     /locus_tag="KRH23_003319"
     CDS             complement(6529..8184)
                     /locus_tag="KRH23_003319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PocR ligand-binding domain-containing protein"
                     /protein_id="HHS5226591.1"
                     /translation="MVDFIESNNEVQKFDWGEVMWIHEPSKTQFNRLSAGIVRFFPGN
                     CQEKHFHLSEEQLLYVIQGEGIQIIDGKKVNIKETSIVYCPPYSEHEIINTGKIDLVI
                     LITYVPHKFSSLRQIPIVFSENNIQELVNVNIIENLANQISNILKLRISVYDLKYKEI
                     FETKKENKFCDICKNIKPCTKKLVKSINNDNFEKVYHCEYGISSLEIPIVLEENIVGY
                     IECGNFIVYKSIYIDKNLSELSSSSGIDIKYINKIYNEFPLNPKSRLYVLKENLLMMS
                     EFIQEIAKRNFFENQLSIKDEEILKSRKENIRLEEALKKANSRLLEEEYIINPIDMFN
                     NSSKEYPFELELYIEKEIKNMNLEGVYNLIDTNKLRYNDVRDTIQEMIFVLSRTVLRD
                     LEDLKLISYLRNKYNKKISLVNSDEDLWNVLFEFSKECIDKNRAFWRKDKGNLIENIN
                     EYIKKYYKENINLNSISDVFFISPNYLSSIFNERNKVSITEYINLLRIEESKKYLLDR
                     SMSISDICKKVGFNNSSYFSQIFKKFNSITPNEYRKNMLDNKY"
     gene            complement(8413..8781)
                     /locus_tag="KRH23_003320"
     CDS             complement(8413..8781)
                     /locus_tag="KRH23_003320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HHS5226592.1"
                     /translation="MKYSITDVSKITKISSSAIRFYEEKGLLLPINRKPSGVRYFSEE
                     DVERLIFIKELKNTGLSIKDIHECFHFCDMGDGTIDKRIQLFQQHKQNIKNKIHELES
                     CMDKIDEKIYYLKEKKMCKK"
     gene            8930..9724
                     /locus_tag="KRH23_003321"
     CDS             8930..9724
                     /locus_tag="KRH23_003321"
                     /EC_number="4.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016830 - carbon-carbon lyase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HpcH/HpaI aldolase family protein"
                     /protein_id="HHS5226593.1"
                     /translation="MEKYATMIKEKLNEGKVLCGVAVSLSDSVVSELIGISGYDFIWI
                     EGEHGALDRKDIQQHMIAAHAGGAASLVRLVNSDPDLVKPIMDMGTDIICFPFINTVQ
                     DAQKAVAACTYPPNGIRGYNPQRASYYGNMNYFDYVKNANNETLKMMLIEQKAGYDNL
                     EEIVKVEGIDIIALGPGDLSLDMGFSGYMNRIEIKDMISHAAEICKKYKMPFIIFPTI
                     EKKSIEEWVNIGANMLCFAQDTTFITYVINQLLSFYNEIVPIQKQH"
     gene            complement(9877..10305)
                     /locus_tag="KRH23_003322"
     CDS             complement(9877..10305)
                     /locus_tag="KRH23_003322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HHS5226594.1"
                     /translation="MSKIYIVYWSGTGNTEKMANFVAEGVKLKGKTPEVLDVSLLKPS
                     DLKEEDKFALGCPSMGAEQLEEGYMEPFVSELESMVSGKQIGLFGSYGWGNCEWMRDW
                     EERMQNAGATIIGGEGITAMEDPNEEAKDECIELGKTLAE"
     gene            complement(10781..11719)
                     /locus_tag="KRH23_003323"
     CDS             complement(10781..11719)
                     /locus_tag="KRH23_003323"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family peptidase"
                     /protein_id="HHS5226595.1"
                     /translation="MNKRMKLIPYEINENLRGAKNKFPYGIKQMNARGMWDEGYTGKN
                     IVVGIIDTGCDISHPLLKGKIIGGANFSDDSNGNKNIYEDFNGHGTHVAGIIAASNYN
                     NEVMGVAPDCKLLIAKALNKDGTGTYQSIINAINFAVNNKVDIISMSLGGNKDDKNLK
                     NAVMQAVKNNISVVCAAGNNGDGDSSTSEYSYPASYAEVIEVGAINENYLVEKFSNSN
                     TTIDLVAPGRNIISTYMDNKLAIMSGTSMSAPYVSGSLALIKEWAREEFERDLDEAEL
                     YAQLIKCTRALGIPRTEQGNGYLYLNLYKYKNNGKR"
     gene            complement(12233..13045)
                     /locus_tag="KRH23_003324"
     CDS             complement(12233..13045)
                     /locus_tag="KRH23_003324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HHS5226596.1"
                     /translation="MFYNAKSCQMMIGSNTVNYIEFGSGKKTLIILPGLGDGLFPLHG
                     KIQAIAFAFRYKQFAKDYKVYVFGRKNQITEKYSTRDMAKDQADIMKKLGIMKAEVMG
                     VSQGGMIAQYLAIDYPELVEKLVLAVTSSKQNDTIQNVICSWIDMAKKQNYNGLMIDT
                     AKKSYSERYLKKYQLFIPFLGKVGKPKDFKRFIIQATSCIEHNAFSELNKITCPTLII
                     GGANDKIVGNNASFHLAEKIKKSEIFIYEGLGHATYEEAQDFNERVLEFLNK"
     gene            complement(13068..13700)
                     /locus_tag="KRH23_003325"
     CDS             complement(13068..13700)
                     /locus_tag="KRH23_003325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HHS5226597.1"
                     /translation="MNREEKSKNSKEKIIQSAFSLFSSKGYDSTSTQDIINLSGLSRG
                     AMYHHFKTKEDILRSVTKELYSQMNNFLEHLVADDTLTANEKIIELVVHSANDYTRRK
                     MVHCSWLEKIPFSLIEEVRNLNNVVAPNIAKIIKQGVENKEFSCEYPEELAEMLVFSI
                     DILLDPVLFKREYSEVCNRLDFLLFMLKKMDIPLIDEYGIQKFKDLFRQL"
     gene            complement(14044..15699)
                     /gene="ilvD"
                     /locus_tag="KRH23_003326"
     CDS             complement(14044..15699)
                     /gene="ilvD"
                     /locus_tag="KRH23_003326"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004160 - dihydroxy-acid dehydratase
                     activity [Evidence IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0009082 - branched-chain amino acid
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HHS5226598.1"
                     /translation="MRSDIKKGIEGAPKRALMYGMGLTKEEIERPLIGIVNAQNEVIP
                     GHLHLDEIAEAAKNGVRMSGGLPLEFPAIGVCDGIAMGHVGMNYSLASRELIADSIEA
                     MAMAHGFDALVLIPNCDKIVPGMLMAAARLNIPSIVVSGGPMLPGKKNGKVYDFNSAM
                     EGVGACKDGTVSEEELEALAMNSCPGCGSCSGLFTANSMNCLTEALGMGIPYNGTAAS
                     HSGERKRIAKYAGMYVMELLKNDIKPRDILTIDAFKNAIAVDMAMAGSTNTVLHLPAI
                     AYESGIELNLDFFDEISEKTPCLTKLSPSGKHHIEDLHMAGGIPAIMNELSKINGINL
                     DCKTVTGKTIGENIRNCEIENEEVIHTLKNPYSNQGGLAILKGNLALNGAVVKKSAVA
                     EEMLVHEGPARVFNSEEEAVNAIFGKKINKGDVIVIRYEGPKGGPGMKEMLSPTSAVA
                     GMGLDKHVALLTDGRFSGATRGASIGHISPEAMEGGLIGLVEEGDIISINIPDKKLEL
                     KVDEVEIENRKLKFKPLEPKIKHGYLSRYAKLVTSANTGAVLK"
BASE COUNT         5494 a         2532 c         1641 g         6059 t
ORIGIN      
        1 attgatttct agagaaccct ttttagtttt atctacattt atattaatat atagcaatgt
       61 aaaacactta aatatatttt taatattaag aataactaaa atgttaacta aaaaatataa
      121 ttaagtagac atttctatta atctatgata caatagtatt tgtggtaata cacaattaaa
      181 tcaagtatat cttgatatag gttaatagga gtatttttaa tgaataatgg aatagtgaaa
      241 tggtttaata atgaaaaagg attcggtttt atatcaatgg aaggtagaga tgatgtgttt
      301 gctcatttct ctgctataca aacttcagga tttaaatcat tagaagaagg tcaacaagta
      361 agctttgata tagttaaagg tgctagaggt cctcaagcag aaaatataac tatattataa
      421 tatatagatt tttcgggaaa gactctttta gagtcttttt ttattgttaa tatatgtaag
      481 ataatcattg gtgaagtaaa taaggtatat tgagtaatgt tcttgatagt ttatatgcta
      541 atgaatttca aaaaaataag cactcctata aaaagagtgc tcttaatgta aatataaacc
      601 ttcattggtc cagcctaata ccccgtattc tccaagttct aactcttttt tatatacatt
      661 atcactttca gccatatcta acacaatcat ttcttcttta gaatcaattt gtaaaatatg
      721 aggactgtgt gttgtgacaa ttatttgtgt ttttaggaga attgttttta atgtaataaa
      781 aattttacat accacatagt tgatataaaa cttccgccaa caacaccagc tattgcaatt
      841 cctatagatt ttacatacca catagttgat ataaaacgca gagtaaagaa actgaaatag
      901 tgacttttta tatttttaca taccacatag ttgatataaa actatattac gagaaaaatt
      961 taaaaacgac taaaatctat tttacatacc acatagttga tataaaaccc caaaataaac
     1021 ttagcatctc caatgtttac acatatacaa tgctcttaaa attgcagtga acgcgcaata
     1081 gtgcaattga taatacttat catatattct caatacctta tatttcaact gctaaacctc
     1141 aatttatcac aaatatcgct cactgcaaaa tttctatatt tttattatat catagcatat
     1201 aattaatatt ttcaattaat ttttacattt aattatgttt aaattctata ataatgcaac
     1261 tttaatgttt ctttctggaa ctaatataaa aactatttca gaaagattag gtcatgcaga
     1321 tataaaaata actatgaata gctactctca gtttttagaa gagatgaaca gagaagcatt
     1381 tgaaaatttg agcaaaatac tatttattgt attttaaaga agatgactta ttcaatattt
     1441 gatgctagaa tataattaat aaaaatttaa ttataggtga ttgtattatg aatattatta
     1501 aaagcataac tttactctta acattattaa ttgtgatatt aatgacaggc tgttccccaa
     1561 gagaaagtgc tagtgaagtt gcaaaaaaat atattgataa gatgaactct ggtgactatg
     1621 aaacagcata tagtttatta agtaaagata gtaaaaaaaa aattagtata gaaaatcttg
     1681 aagaatttca aaatatttta gttagtacaa aaagaataat tagttataaa ataggtaaag
     1741 aaaaaatcat aaaaaaatat aaacatgatg gaaaagaata taaaaatgtt gttaaattag
     1801 aagaaacttt taatataaaa aaccttcttt ataaaaaaga tgattctcta aaagtaaata
     1861 gatattttgt agttgaaaat aacaaataca agctattatt gtatgaaagt ttcaaaaaag
     1921 aatttggtat taatagtatg gaccttgctc aacttaagct taatgatttt ggactaaaat
     1981 actttaaaga agttgacctt atactaaaaa aagctattgc tattaatcct actgattcaa
     2041 agctttatta tgcccaagca tgtaattata tgaattttga tggatttcct ggttattcag
     2101 atacaacata taatgcttta gattcaatta ataaatcttt aaagtattta gataaaaatg
     2161 attctgacta caaaaaaaat gcaagtaata tatataactt aaaaggagtt attcttatgt
     2221 ttcacaaaag atttgatgaa gcacaacaat atttaaataa agccttatac tttaacaaag
     2281 ataatgaaga cccaaaatat aatctaaata caataaaaaa acatctaaac tagatattta
     2341 atttttgaat ttataaaata ttttttatgt ataattcagc actgaatcat aatctctact
     2401 aaactaatta caagtttaaa ttataaagac ttatttctat ataaatatta ctctataaca
     2461 ataagtttct tatttaaatt ttaaaatatt atctaaaaat cataaaaaag aaggtataaa
     2521 gagctaccct caagctcaat ataccttata aatatctaaa cttcattttt tactaatttt
     2581 tctatatctt tgataatatg ttctttagat ttttttccag ctatggcatc aaaaattgca
     2641 acagcctttt tctctccaaa cttttctgct acatcattaa agtctaaaaa tctaacactt
     2701 tcttttggtt taccaaacat ataacacctc tcatacattt ttatatattt attataactt
     2761 ctatagactt atttttcacc aataaacgtt agacaaatta gtccctttat ttttttaaac
     2821 tagctttacc ttcaaaattc ttaacaaaaa cagtttattc tactctataa ataaaaatag
     2881 acaatttaat ttgtaggaaa ctgataatag aatacagtaa ataaaacttt gtttaatcta
     2941 tctgaaaaag ttatctatta aaactgctat gaatttataa agaatattct agttcataaa
     3001 aatacaaata tgtaaatata atcaccttaa tattaattta tttaaaataa aaaatgtata
     3061 aaagatttaa taatgaaaat atactattct caatacaatc tatgatgcaa ataatttaaa
     3121 actactatat tatttaaaaa tttatattta tatatgcaat tctaaaaact taataagaag
     3181 tgaacttaga aaataaagct tcatttcaaa gacttaaata gactattatt attagtctaa
     3241 ataaactacg tctatcaaaa ttatatatta aattcttcta aaatttttat tgcaaatctt
     3301 gcgtttggat atgtaataga cccgccacca attacaccta tttttatagc ttctataatt
     3361 tcatctttac ttgctccaga attaatacaa ccctcaatat gataacaaat acactcatca
     3421 catcggctta aaattgaaat agctagtccc attaattcct tatttttttt gcttatagcc
     3481 ccttctgaat aagtcttatc atcaagactt ccaaatactc taaaaaactc atctgtttcg
     3541 cttaattttt tattgtaaaa tcccctatat tctttcattt ctctaatatt catcttctac
     3601 ctcctatgtt tttcttataa gaatatcaca ccgtacttat attttcaata ttaaatacaa
     3661 attttcattt tatgttcatt agcctaattt atattatttt ttgaaatctc aataagttat
     3721 catataagta agattttttc agaactaaaa tagaaatctt agtaatttct ttattatcta
     3781 tctcagttct gaaatatatt attcttatcc aaacattatt atagtgatta attatattag
     3841 ttatttttac ctgaaatttt atacatcaaa taagaatata taaatggtag tattacaatt
     3901 acaaagatta caaagatatt ataaaaagga atattaataa atgcattaat aattaataat
     3961 attccaccaa taagccaaat ccatccagct aaatggtgtg tcttattcca attatcttca
     4021 tcattaagag tccatggtaa aattattcct actgagtaat ttcgtttaca tttaggaaga
     4081 tagtttccaa ataaaataac tattattcct aaaattaatc ctgtataaaa attagattcc
     4141 aaactaactc ctgttgaata taaaaccatc attatttgta taattactga aagtatagca
     4201 actccccatt ttgataaatt ttgtataaca tttgaaaaat tagctttctt aggctcattc
     4261 tcaagtctaa accatgtata caaatggata catagcatta acaatggtac accaaaagct
     4321 gctataacct ttggagcata attatctgga tttccataat tatcaaaatg aattgcaact
     4381 tcatttggta atctattata aaaatatatt gatacaataa atggtataaa acatattaaa
     4441 gtagataaaa taaattgttt atttatcgct tttttcatta tctttttctc ccttctccat
     4501 aaattgtgaa aaccaaagca taacctcttc gaaaactgaa atatttattt cgtagaaaat
     4561 aaagttctta tactttgttt caaatatgag tcctgccttt tttagttgag atagatgata
     4621 agaaattgta gcattcgtca tattaaattt ttcactaatt tctcctgctg acattttatt
     4681 ctccctcaac ataaccaata tttctcttct tatagggtct gaaagagctt tgaatgtttc
     4741 tggaaacccc aacaccatca cctcgctatt tagaatttca tctaaataga atataacata
     4801 acatccattt tatttcaata actatttaga aatttttcta aatagttatt tctaaatatt
     4861 tattgaaaat tttcatatta agattctcaa tttacttaag tcgcttttat ttaatcttac
     4921 tttatctaat ttttttaact taacaaaagt gtattgcacc ataattgtta aagcaaaaac
     4981 ctaatgactg aggtacttat atataacaat acttttaatt ttaaattaaa agtagctaaa
     5041 cccaatttaa aaagtagtta agtcctattt aaatagaaaa gaatgaaacg agaaatatac
     5101 tgtataaaag tacataaaaa catctactaa ttagatacaa ctataacaga atatatttat
     5161 tattataata acaaaagaat aaaaaaaatt aatttagcat aaccttgtta aatatagatt
     5221 tgaatatgaa tttaaagtta tgtaaaatta aaaatacagg aatgaaaatt ccattcctgt
     5281 ataaaatcta acttttgagt ctcagtacaa tcttattttg agacaatctt ttttgtttta
     5341 tattttctta tatttaaaat ataacgcata tcttatgcaa catattcata tttttcttta
     5401 tattctttca tcgcatcatt ccaagcgtct tgtactgtta cacctctttt attagcaatt
     5461 ttttgtgcca gttcaattat cttcatagct cttcttgata tgttcataaa cattcctcct
     5521 acaaattacc atatatttca tatatataaa tcaaggttat atttttatga tatataatcc
     5581 ttctattgta agattacagt ttatatgtgt attatatatg aactatatta gaagataatt
     5641 agaattttta taaagctata tgattagatt aaatataaaa gctttacaat tacttataaa
     5701 tttaaaaagt ctataagcta aactaatgtt tgatatacca attttacgac cataaataat
     5761 gccattacta aaaatattgg ttttatcatc tttgaacctt tctttatagc aactttagca
     5821 cctacataag ctcccattat catcactaat gcaaacacta tagcaatttt ataatctact
     5881 tgaccattta tcatgaataa taacaatgaa gttatattac ttgttaagtt taatattttt
     5941 gtatttgcag aagcatgtaa aaaatcatat ccatatattt ttataaatcc aaaagtcaaa
     6001 aaagttcctg tacctggacc aaaaaaacca tcataaaaac ccattataag agccataagc
     6061 atccctagtc ttaaattttt cttattaaca gcttcaaaat tatcttcttg acctaaattt
     6121 ttagaaataa aggtgtaaat agccactatt aaaatcataa ccacaaccaa aacatttaat
     6181 atctcttcac ttattgataa tacacatctc acacctagaa cactaccaat aatagtaaat
     6241 ggtactaatt tttttaaaag gtcgttatta atttttccag actttgaata tctataggca
     6301 ctacttatac atcctgctga tgctgcaaat ttatttgtac caatggcaag atgtactggc
     6361 actccaattg ccataagaac aggcatgctt ataagtcctc ctcctcctgc tatagaatct
     6421 acaaaagcag ctaaaaaccc ccctatacat aaaaaaataa ctgaaaacat aaaattcctc
     6481 catcattctc tttcaatttt tcttacaata tatattatat aatcttattt aatacttatt
     6541 atccagcata ttctttctat attcatttgg agttatacta ttaaacttct taaatatttg
     6601 tgaaaaataa ctactgttat taaaacctac tttcttacaa atatcactaa tactcatgct
     6661 tctatctaac agatattttt tagattcttc tatcctaaga agatttatat actcagttat
     6721 tgaaacttta tttctttcat taaaaataga actcaaataa tttggactta taaaaaaaac
     6781 atctgatata ctattcaaat ttatattttc tttataatat ttttttatat attcgtttat
     6841 attttcaatt agatttcctt tatcttttct ccaaaatgct ctattcttat caatacactc
     6901 tttggaaaat tcaaataata cattccataa atcttcatca ctgtttacaa gtgatatttt
     6961 tttattatat ttatttctta aataagatat aagttttaaa tcctctaaat ctctaagcac
     7021 tgttctagac aatacaaata tcatttcctg aatagtatct ctaacatcat tatatcttaa
     7081 tttgtttgta tctattagat tataaacacc ttctaaattc atatttttaa tttctttttc
     7141 aatataaagt tctaattcaa agggatattc ttttgaagaa ttattgaaca tatctatcgg
     7201 attaataata tactcttctt ctaataatct actatttgct tttttaagtg cctcttcaag
     7261 tcttatattt tcttttctac tcttcaatat ctcctcatct tttatactaa gttgattttc
     7321 aaagaaattc ctcttagcta tttcctgaat aaattcagac atcattaata aattttcttt
     7381 taatacatat aatctacttt taggatttaa tggaaattca ttgtaaattt tgtttatgta
     7441 ttttatatca ataccagaac tacttgataa ttcagataaa tttttatcta tataaataga
     7501 cttatatact ataaaattac cacattctat atatccaact atattttctt ctaatactat
     7561 aggtatctct aaactggaaa taccatactc acaatggtac actttttcaa agttatcatt
     7621 atttatgctt ttaacaagtt ttttagtaca cggttttata tttttacaaa tatcgcaaaa
     7681 tttattttct ttcttagtct caaatatttc tttatacttt aagtcatata cagatattct
     7741 aagcttcaat atattagata tttgatttgc aagattttca attatgttta cattaactaa
     7801 ctcctgtata ttgttttcag aaaatactat aggtatttgt ctcaaactcg aaaatttatg
     7861 aggaacataa gtaattaata ttactaaatc aattttacca gtgtttataa tttcatgttc
     7921 tgaatatggt gggcaataaa ctatagatgt ttcctttata ttgacctttt taccatcaat
     7981 tatttgtatt ccttctccct gaatcacata taaaagctgt tcttcactta aatgaaaatg
     8041 cttttcttgg cagtttcccg gaaaaaatct tacaattcca gcactaagtc tattgaattg
     8101 tgtttttgat ggttcgtgta tccacataac ctctccccaa tcaaattttt gtacttcatt
     8161 atttgactca ataaaatcta ccataaactc acctcgtagt ttttatctaa atattttttt
     8221 attcctttaa atatctcctt ataatataca ttatcataat tttctttttt attgtataga
     8281 taaatagtta tatagaacat tgtccaattc ttcctaaaaa tatggtgtaa aaaatctttc
     8341 ctcaaatgtt tccaattgaa tttactcttt atattagaaa aatcaaaaaa ttattttttt
     8401 attctataag gattattttt tacacatctt tttttctttt aagtaatata ttttctcatc
     8461 tattttatcc atacagcttt ctagttcatg tattttattt ttaatgtttt gcttatgttg
     8521 ttgaaataat tggattcttt tatctattgt accatctccc atatcacaaa aatgaaagca
     8581 ttcatggata tctttaatag ataaaccagt attttttaat tctttgataa atattagacg
     8641 ctctacatct tcttcagaga aatagcgaac accacttggt tttctattga taggaagtaa
     8701 taaacctttt tcttcataaa atcgaatagc agatgaagaa atttttgtta tttttgatac
     8761 atcagttata gaatatttca taatctctac ctccctaaat tttatatgaa taagaatatt
     8821 ataaaaatac cttatacagt agtcaacaaa aaagtattga cttcaagtta ggttgaagtt
     8881 gtactctttg aagtgtaaaa gaaaacttac aaaagaaagg atgatataaa tggaaaaata
     8941 tgcaactatg attaaagaaa agttaaatga aggaaaggtc ttatgtggag tagctgtttc
     9001 actgtctgat tcagttgtaa gtgagttaat cggtatatct ggatatgatt ttatttggat
     9061 tgaaggagaa catggtgctt tagaccgtaa agacattcag caacatatga tagctgcaca
     9121 tgctggtggc gctgcttctt tggtacgatt agtaaacagt gaccctgacc ttgttaagcc
     9181 cataatggat atgggaacag atattatttg tttcccattt attaatacag tacaagatgc
     9241 acaaaaagcc gtagcagctt gtacttatcc tccaaacggt ataagaggat ataatcctca
     9301 aagagcctct tattatggga atatgaatta ttttgactat gtcaaaaacg caaacaatga
     9361 aacattaaaa atgatgttaa ttgaacagaa agcaggttat gataatcttg aagaaatagt
     9421 aaaagtcgag ggtattgata ttatagcatt aggccctggt gacttatctt tagacatggg
     9481 tttttccgga tatatgaata gaattgaaat aaaagatatg atttctcatg ctgctgaaat
     9541 atgcaaaaaa tataagatgc cctttattat ttttcctaca atagaaaaga aaagtattga
     9601 agaatgggtt aatattggag caaatatgct ttgttttgca caagatacta cctttatcac
     9661 ttatgttatc aatcaattat tatcttttta taatgagatt gtaccaattc aaaaacaaca
     9721 ttaaattata aatctaattt tatattaaaa gagactaata ttttatctat ctctattaag
     9781 gatattttct tatgtatcat aatattagtc tctcttatta ttatatactg ctatcatcat
     9841 tagttgctat ttatactatt tttataatat acaaatttat tcagctaacg ttttgcctaa
     9901 ttctatacac tcatcttttg cttcttcatt tgggtcttcc attgctgtaa ttccttctcc
     9961 accaataatt gtagcaccag cattttgcat acgttcttcc cagtctctca tccattcaca
    10021 atttccccat ccatatgaac caaataatcc aatctgttta cctgatacca tagattctaa
    10081 ttctgaaaca aatggctcca tatacccctc ttctagttgc tctgctccca tagatgggca
    10141 acctaatgca aatttatctt cttcttttaa atcacttggt ttcagtaagc tcacatctaa
    10201 aacttctggt gtcttacctt ttaacttcac accttcagcc acaaaatttg ccattttttc
    10261 agtatttcct gttccactcc aataaacaat atatatttta ctcattttta cctcctgtag
    10321 tattttttaa ttaatcaata gttagttata gctaactaac atctaaaaaa caaaagattt
    10381 ctttatctga aatctcttta tttttctaaa tatagaatat catagttgat tttgaaattc
    10441 aatacttatt gataatattt atcatttata ttttatattc attttataat atcaaaacac
    10501 tgtatcgtat ttctaatctt tcatagaaaa atttctaact tatagtactt ttgcatctct
    10561 tataaatctt ttatatgtat aagtacatag aaaaacacac cttttccaga tgtgctatct
    10621 ataatatcgt atatttattt ttcaattcta actagctaat atgtttataa attttatcac
    10681 ttaatacctt tatacattga tgtaaaatct tacacctaag taatttttat tatttgtcta
    10741 gactctatat aatatagcta ttttatcatc aaatcaaaaa ttatcttttg ccattattct
    10801 tgtatttata aagatttaaa tataagtatc catttccttg ttccgttcta ggtattccaa
    10861 gcgctctcgt acattttatt aattgtgcat acagttcagc ttcatctaaa tctctttcaa
    10921 actcctctct tgcccattct ttaattagtg ctaatgagcc tgatacgtat ggtgcactca
    10981 tactagtacc actcataata gcaagtttat tatccatata agtcgatata atatttcttc
    11041 ctggagccac caaatctatt gtagtatttg aattactaaa cttttcaacc aaatagtttt
    11101 catttattgc acctacttct attacctcag cataactggc tggataacta tactcacttg
    11161 tactagaatc accatctcca ttattacctg ctgcacacac tacagaaata ttatttttta
    11221 ctgcttgcat gacagcattt tttaaattct tatcatcttt gtttccccca agagacatag
    11281 atataatatc aaccttgtta tttacagcaa agttaatagc attaattata ctttgatatg
    11341 ttccggtacc atctttattt aatgcttttg ctattaataa tttacaatct ggagctactc
    11401 ccataacttc attattatag ttagatgcag ctataatacc cgccacatga gttccatgac
    11461 cattaaaatc ctcatatata tttttatttc cattactgtc atcactaaaa tttgcaccac
    11521 caattatttt tccttttaaa agaggatgag atatatcaca acctgtatct attataccaa
    11581 ctacaatatt tttaccagta taaccttcat cccacattcc cctagcattc atttgtttta
    11641 ttccatatgg gaatttattt tttgcacctc ttagattttc atttatttca tacggaatta
    11701 gtttcattct tttattcatc atatatcctc ctaaaaattt tattgcttat aaaaatcatg
    11761 aattttattt tataataggt ttataaatca aattaaaacc tatatctact tatttatatt
    11821 tatgatatat tttttatttt taggagtcat attttattgt atataaaata atatttagat
    11881 aactatatta aaaaatacat gtttgcttat atacaaaact tactaaaatg tctttaatat
    11941 ttttgtatac aaacattata tttttattat aaaaagctca taaaaatttt gattatattt
    12001 tcataagtta acaaatgtgg gtataatatg aatttacaaa attcctctgt ttgtataagt
    12061 gctttactaa tacactaata tataatcaca ttgaagctat atttgtattt atagtagaca
    12121 atgtatcaaa aattggttat gaatagtaaa aataccagtt aagcatattt tcatgtttct
    12181 atttttaaca ttaaatttcc aatcttcata tgtatatttt taacaaaggt gtttacttat
    12241 ttaaaaactc taaaactctt tcattaaaat cctgtgcttc ttcatatgta gcgtgtccca
    12301 atccctcata gataaatatt tcgctttttt taattttttc tgctaaatga aaagaagcat
    12361 tatttccaac aattttatca ttagcacctc ctataattaa ggttggacat gttattttat
    12421 ttaattcgga aaaagcatta tgttctatgc aagaggtcgc ttgaataata aatcgtttaa
    12481 aatcctttgg tttacctact tttcctaaaa aaggaataaa taattggtat ttttttaaat
    12541 atctttcaga ataggatttc tttgctgtgt caatcattaa accattgtaa ttctgcttct
    12601 tcgccatatc aatccaacta caaataacat tttggatagt atcattttgc tttgaagaag
    12661 taactgccaa cacaagtttc tcaactaact caggataatc aattgccaga tattgagcta
    12721 tcattccacc ttgagaaaca cccattactt ctgctttcat aattccaagt tttttcatta
    12781 tatctgcttg gtctttagcc atatcccttg tggaatattt ttctgtaatt tgattttttc
    12841 taccaaacac ataaacctta taatcttttg caaattgctt atatctaaaa gcaaaagcaa
    12901 tcgcctgtat ttttccatgt aaaggaaata aaccatctcc taatcctggt aaaataatta
    12961 gtgtcttctt accactacca aattcaatat aattcactgt attacttcct atcatcattt
    13021 gacaactttt tgcattataa aacatagtct attcctcact tttcctatta taattgtcta
    13081 aataaatctt taaatttttg aataccatac tcatcaatta gaggaatatc catttttttt
    13141 aacatgaata ataaaaaatc caacctatta catacttcac tgtattcacg tttaaataat
    13201 acagggtcaa gtaaaatatc aatactaaaa acgagcattt cagctaattc ctctggatat
    13261 tcacaagaaa attctttatt ttcaacacct tgtttaatta tcttagcaat attgggtgca
    13321 actacattgt tgagattacg aacttcctct attaaagaga atgggatttt ttctaaccag
    13381 ctacaatgta ccatttttct acgtgtgtaa tcattcgcac tatgaacaac caattctatt
    13441 attttttcat ttgctgtaag ggtgtcatca gcaacaagat gctctaaaaa attattcatt
    13501 tgtgagtaaa gttcttttgt gacacttctc agtatatctt ctttagtttt aaagtgatga
    13561 tacattgcac ctctagatag accagataaa ttgataatat cttgtgtaga tgttgaatca
    13621 tatcctttag acgaaaatag tgaaaatgct gattggataa ttttttcttt actattttta
    13681 cttttttctt ctctattcat atttccctcc taaaaacaga ctgtctgttt gttttttatt
    13741 atacatttta atatttatta tgtcaagaat taactgactt tcaatttctt catagttcag
    13801 atggaacgaa aagcattcca catcaaactt ttaaaaagtt gtattacctc aacaaggtct
    13861 aaaagataca tctctatgct gtgctcgtat tccttataat agagatgtat tgttttcaaa
    13921 gataatcaag attttgctgt gtttttcata caaaataaaa aggatacctc attagtgcta
    13981 taacacctaa gatatccaat taatattttc ttaacttttt ctaatttaca taaatatagt
    14041 ctactatttt aaaactgctc ctgtatttgc tgatgttacc aatttagcat atctacttaa
    14101 gtatccatgc tttattttcg gttctaaagg tttaaatttt aattttctat tttctatttc
    14161 aacttcatct acttttaact ctaatttttt gtctggtatg tttatagaaa ttatatctcc
    14221 ttcttcaact aacccgatta aaccaccttc catagcttct ggagaaatat ggcctataga
    14281 tgctcctcta gttgcccctg aaaaacgacc atcagtaaga agtgctacat gcttatcaag
    14341 tcccattcct gcaactgctg atgtaggaga tagcatttct ttcattcctg gaccaccctt
    14401 tggaccttca tatcttataa ctataacatc acctttgttt atttttttac caaaaatagc
    14461 atttacagct tcttcttctg aattaaaaac tcttgctggt ccttcatgaa ctaacatttc
    14521 ttctgcaact gctgactttt ttacaacagc tccatttaga gcaagatttc ctttcaatat
    14581 tgcaagccca ccttggttac tatatggatt ctttaatgta tgtattactt cttcattttc
    14641 tatttcacaa tttcttatat tttcccctat agtcttgcct gttacggttt tgcaatctaa
    14701 atttattcca tttatctttg aaagttcgtt cattatagct ggtattcctc ctgccatatg
    14761 taaatcttca atatgatgtt ttccacttgg acttaatttt gttaaacaag gagttttttc
    14821 acttatttca tcaaaaaaat ctaagttaag ctctattcct gattcataag ctattgcagg
    14881 taagtgaagt actgtatttg tagagccagc cattgccata tccacagcta tagcattttt
    14941 aaaagcatct attgttaaaa tatctctagg ttttatgtcg ttcttaagta actccataac
    15001 atacatacct gcatattttg ctatcctttt tctttctcca gaatgtgacg cagcagtacc
    15061 attatatggt atacccatgc ctaaagcttc tgttaaacaa ttcatgctat ttgctgtgaa
    15121 aagaccagag catgaaccac atccaggaca agagttcatg gctaacgctt ctaattcttc
    15181 ttcacttact gttccatctt tacatgctcc aacaccctcc attgcagagt taaaatcata
    15241 tacttttcca ttttttttac ctggaagcat aggccctcca ctcacaacaa tacttggtat
    15301 attaagtctt gcagcagcca ttaacatacc tggcactatc ttgtcacaat taggtataag
    15361 taccaaagca tcaaaaccat gtgccatagc catagcttct attgaatctg ctattaattc
    15421 tcttgaagcc agggaataat tcattccgac atgccccata gctataccat cacatacccc
    15481 tatagcagga aattctaatg gcaaaccacc actcattctt actccatttt ttgcagcttc
    15541 tgctatttca tcaagatgca gatgaccagg aatcacctca ttttgtgcat ttactatacc
    15601 tattaatggt ctttcaattt cttctttagt aagacccatt ccatacatta acgctctctt
    15661 tggagctcct tctattcctt tttttatatc acttctcata atattacctc tttcttactt
    15721 ttttaa
//
LOCUS       DAEORM030000076        15656 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.079, whole genome shotgun sequence.
ACCESSION   DAEORM030000076 DAEORM030000000
VERSION     DAEORM030000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15656)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15656)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 15656)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15656
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.079"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            complement(207..518)
                     /locus_tag="KRH23_003327"
     CDS             complement(207..518)
                     /locus_tag="KRH23_003327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226599.1"
                     /translation="MKKIIKSFTFWFFLIALFEIYMHQIGQDSKSIVLIGLNPILSII
                     SRVDSFFVFMDSGMQIPCRTITGSISIYWYIASILSFLIYGIILDLIRIVISKIGNKT
                     K"
     gene            complement(574..1167)
                     /locus_tag="KRH23_003328"
     CDS             complement(574..1167)
                     /locus_tag="KRH23_003328"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HHS5226600.1"
                     /translation="MISDSISKRRSIRKYKNQSISHETIEKIIEAGINAPSSKNRQPW
                     RFVVITEKEKESMLKAMRKGIQNEINDNGLLPGSRQHIAGANYTVEIMKQAPVTIFIL
                     NILGKSPLEKLSPEERFYEMANMQSIGAAIQNMSLTAVELGLGSLWICDVYFAYRELC
                     EWLNTDSQLVAAISLGYPDEEPSRRPRLQLSDVTEWR"
     gene            2011..2661
                     /locus_tag="KRH23_003329"
     CDS             2011..2661
                     /locus_tag="KRH23_003329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YidC/Oxa1 family membrane protein insertase"
                     /protein_id="HHS5226601.1"
                     /translation="MDFISSILQGLLSILFNFTGDFGISIVLITLIVKLVLMPLSLKQ
                     RFSVKKQQELAEKMEYIKEKYKNDTKELEKQIQVSSVESMKSMLGCLIVLVQMPVVYA
                     LYHVCLDMTKEFTTIIIPWIANLGTFDNLFILPCIYTLIMLASNLVNYIPYLKINSQV
                     KFNKQMAVVTTITSLILTVRTPVAIGLYFITSAIYSLIEDICFRIYFNRKNRIVTK"
     gene            2875..3546
                     /locus_tag="KRH23_003330"
     CDS             2875..3546
                     /locus_tag="KRH23_003330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HHS5226602.1"
                     /translation="MAKILIVEDEKRMQSIIVEYMQKGGYTCITADDGVEALTILKSN
                     NIDLMILDIMMPYLDGFSVCRVSREMTNIPIIILTAKGEEEDKLKGYEYGADDYITKP
                     FSPKVLLAKVNALLRRYTTDIPKNSLSLGKIFIMVASRQVYVEDKLIDLTYKEFELLR
                     LFMENPNQVFSREKLLNCIWGYDFEGNTRTVDTHIKTLRKKLGSEGHHIVTLIRSGYK
                     FEVKE"
     gene            3543..4673
                     /locus_tag="KRH23_003331"
     CDS             3543..4673
                     /locus_tag="KRH23_003331"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HHS5226603.1"
                     /translation="MNSLRKIIEKLKNVDISNWIKQNFGLYSVRKKVFLLSKLSGALI
                     ILFYLVVEEFSINSKFEFWIWFIILVIFIMSIDFLLGKFISEPITSINKSAKSMSQLD
                     FSNPCTVNTNDEFGELSRSLNTMSTNLQQALSDLESANIQLEKDVNKERMLLEQRKEL
                     VDTISHEMKTPLGIIRAYTEGLMDEVDEEKKKNYMNVIIEETDRMNNMIVSLLDLSAL
                     EAGVSKLNPERFDFIEFVETVAGRLLIDIPDANFYFTYDLPEYEVFVVADKMRMEQVV
                     ENLVINAKKHVVYNGNLDLSITCENGLLLFEIYNDGRFIEQDEISKIWSKFYRSVQSQ
                     RTGGSGLGLAIVSQILTMQGLEYGVNNRDRGVEFYFMIPIDE"
     gene            4984..5106
                     /locus_tag="KRH23_003332"
     CDS             4984..5106
                     /locus_tag="KRH23_003332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226604.1"
                     /translation="MKWYTWLTIILIILLSIPLKIKFIKWWDRRQKNDKGGYDR"
     gene            5103..5948
                     /locus_tag="KRH23_003333"
     CDS             5103..5948
                     /locus_tag="KRH23_003333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHS5226605.1"
                     /translation="MIKVGELKFSYGKDKQILHGLNFEVKEGEIFGFLGPNGSGKSTT
                     QKILNGVLKGYNGHVSIFGKEVKAYTESLYQKIGVLFEFPYLYTNLSAIDNLEYFSSF
                     YPKNQRRDIYELLDLLEFKKEFINKPVSSYSKGMKQRISMARALVSNPKLLFLDEPTS
                     GLDPSGAVLFRKIIEEERKKGTTIFLTTHNMLDADLMCNNVAFIADGKIMVIDKPKNL
                     KMKNSNNKVEVEFVYNGNRDIEIVDIQELESGITFKYDEILSVHSKEPTLEEVFIKYT
                     GRMLV"
     gene            5948..6976
                     /locus_tag="KRH23_003334"
     CDS             5948..6976
                     /locus_tag="KRH23_003334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHS5226606.1"
                     /translation="MYSKFFTLVKKDFWMMIYGKFFVLTLGSLILYSCYINFGYVKFM
                     DEDSYHNNVYLYNPENISMSASPLINQVSSIGELKAKLDEDTSAVCIDMSSSKPKVIL
                     HESIKGVDNYRADYALSLLSSEKDHNSKISDNNAIIQINDKDTSEIKQRKDMTCEILF
                     FEIVAIGFLGIASLLFKEKQMGVMRITGILPVKRSLFILSKIFAFFICDLCFTVLLVV
                     FNIGFLEGIKILPQVLVQASILSIIMSLIGIGCSMLLRDFKQFSLIYLVVAVFITTPI
                     FLSANTSFEIDWIKYHPFYHVYSQLKNAFFMNFSKELVYFVVCSLTIIVLFLLVKYIF
                     NKELVREG"
     gene            6979..7992
                     /locus_tag="KRH23_003335"
     CDS             6979..7992
                     /locus_tag="KRH23_003335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHS5226607.1"
                     /translation="MIGLRYQLKSIKKDKMCIISFFLPVVMAILINFMGTIDISSLGE
                     IRFGIVKDTLPVQTEQWLKKYGMVSVYDTKMHLIREIKDIKTDTIGVVRDGKGIKTVL
                     YGNEINAIKNVGKTLPEMFRLKGDLKDVEVTILPKDSILKEFQNVFIAMILITAMFMG
                     CTFNAMNIISEKEDGISFINEVLPQSRSQYIIQKVFLGLLCGCLSSMITVFICLDISI
                     LDMIMMLLLVVFSAFISSLIGLFIGKLSEGLMVGIVYIKIVMILFIGTPLLIYLLGVN
                     TSGIGNLCYIMPSVATFNGIMEIINGNVIIIKDIVILAVHCVVWFMIYIILDKKRKLS
                     FSR"
     gene            complement(8509..9759)
                     /gene="cme"
                     /locus_tag="KRH23_003336"
     CDS             complement(8509..9759)
                     /gene="cme"
                     /locus_tag="KRH23_003336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter Cme"
                     /protein_id="HHS5226608.1"
                     /translation="MENKNTNSTWKKKVILFLASQYISLFGSSLVQMAMIWYVTLQTS
                     SGVWVTVLTVCSFIPQMIISFFAGVWADYYNRKVLIIVSDSTIAISTLVLILFMMSSN
                     GTTSELIAISVISVIRSLGSGVQTPAVNAMIPQLVPEEHLMRFNGINSSLQSIVQFIV
                     PIVAAAILGFGNKINQVLLIDVFTAIIAIVLLIFIKIPKHDIPKQTEKVSFFADMVSG
                     IKYCFSDKFIRKVLFTYGAFMLLCVPSGFLIGLLIERTFGKGYIYLSIIEMIGFLGMV
                     LGGLIIGVFGGFKNRNKTFFLAILSYAIFSIILGLVTQAWQFFIFMFFTNFSIPIIQA
                     SAMTMLQEHVAPQMLGRVLSLPIIIYTGFIPLGMMIFGPMADVISINNLIIIAGIILL
                     FFALAIPYSKQFYKQGISKSNESE"
     gene            complement(9845..10591)
                     /locus_tag="KRH23_003337"
     CDS             complement(9845..10591)
                     /locus_tag="KRH23_003337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HHS5226609.1"
                     /translation="MDTYTTSEVADLIGVHPNTVRLYEELNLIPKPKRNTNGYRIFND
                     FHIEQFRFARTALKIEVVQRGLRKDALEIVRTSANRDFDKAISLVNQYLQQLEIEKSN
                     AEEALTIVAQILNGNTPETNKLFLTRKETAEHLNVTIDTLRNWEMNGLLKVKRKQNGY
                     RVYTDEDIKRLKIISALRCANYSLSAILRMLNALSSNPNTNIKTVLDTPKDDDEIISV
                     CDKLITSLKEAEHNAKTMKSHLQIMKKQFS"
     gene            complement(10763..11785)
                     /locus_tag="KRH23_003338"
     CDS             complement(10763..11785)
                     /locus_tag="KRH23_003338"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="HHS5226610.1"
                     /translation="MNKNNCLDLIFEKVDPSSVGMSSEKLSQLEPLIISQYSNINGII
                     IARKGKVVFEKYYNGYNADNTFHVASVTKSIISALIGIAIDKGYIKDVDQKVVDFFPE
                     YTCSPSEICKKAVTIRHLLTMTAPYPFKNMTESLERLCKQKDWIKYTLNQLGQKGEIG
                     TFKYSSAGTHLLSAIITKTTGKSAREFANEYLFKPIGMKVIPDYDMKDFGFEDFFGKN
                     LKGWAKDRQGYSIGGWGLTLSARDMLRFGFLYLNDGIWNNKRIISKSWIEESVKMNSN
                     EYGYLWWLCKKDGVLWYSAMGTGGNAICCIPQYDLVIAIPSKIVFKPRDRWEFIEKYI
                     LTSIID"
     gene            complement(11785..14205)
                     /locus_tag="KRH23_003339"
     CDS             complement(11785..14205)
                     /locus_tag="KRH23_003339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HHS5226611.1"
                     /translation="MKEIKINGAKIHNLKNIDVSIPKDKLVVATGVSGSGKSSLMFDI
                     VFEEGRKQYLQSLGILAGIDSEDKFDNIQGLAPTIAVQQNIIRQSNPRSTVGTRTNIL
                     NMLTLLYSVEGQIMCTMCDTPVSDNLICNNCGYEEERLRPSYFSYNSSDGMCMKCSGH
                     GAYFEINIEKLVLDKHDTLKQVLDRAKITPGYLRVFSKKFNDYLDIQFLQLPEEIRNE
                     VLYGHYENGKKSSSLSKVFHNRYKRGEDLNGVYTMTACSDCNGFKIGEEARRVLLNGK
                     HIGELGKMTILEIDDFLKLLINQGNLNTFGTNLVNDILSKTQHLIESRLGHLSLYREM
                     STLSGGEMQRLFLNSHLDSEMDSLIYVLDEPTAGLHESEKIDILKSIKKLKDLGNTVI
                     VVEHDKNTIKMAEHIIDIGPKAGVEGGQLVYQGDLEGLLQSDKSLTGQYLSGKYPMPN
                     RTSNKNITHTDKIPCITIQNANTNNLKNVTVSLPLGAMVGISGKSGSGKSSLISDTLL
                     PLLRSQFNNHTINNQTNSSESEIGEEDDYAVVETIADRLIGTKHISGYSEISQSPIGK
                     NMNSTPASYIGIWDKIRTLFAGQPESLERGFTAGHFSFNSKGACPKCSGSGYEKVWLG
                     NNLSIDHICSECQGKRFNDESLSIKYKNKNIHDILNMSVSESVHFFKDIPNIVSHLNV
                     LEQIGMGYIKLGQPTPTLSGGESQRIKLAKEIGKKRNGNILYVLDEPTTGLSLYDTSK
                     LIQLLDELVENGNSVIVVEHDIDVLNVCDWIVELGPEGGDKGGYIIAEGSPKTLKENP
                     KSITGRYL"
     gene            complement(14291..15211)
                     /locus_tag="KRH23_003340"
     CDS             complement(14291..15211)
                     /locus_tag="KRH23_003340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HHS5226612.1"
                     /translation="MTNAKSKKEYLNRICKVQDYIEEHLHEPLSLDELSNIAGFSKFH
                     FHRIFKAIEKETLAQYVNRLKLENATAFLIHRTDMTVTDIAHYFGFTDSAVFSRAFKN
                     YYKISPIKYRNNYSKNCKEPYKISQYNRSISKPKCKNTREVKGEIEILELDNMNTIYT
                     RYTGSYGNLTSTFPKLLERLFTYASEQNLLGLENTQILAIYHDNPQFTQEHQLRTSIC
                     MTIPDNIVVKENDNLGNMIIPSGKYLVGHFDISKSEYSDAWDFMYNEWLSNGNYKLRA
                     SFPFEVYLNNPHNHPQNRHLVDIYLPIEPF"
BASE COUNT         5564 a         2017 c         2410 g         5665 t
ORIGIN      
        1 aataaactaa tttaagaaat atagaaaatt aatttaaaga aatacaatac attaattttt
       61 aagtaacatt aaattaatgt aagtaaaata atgttcatat gaagatttaa aggtgcattt
      121 tctgaagcta agtatatgtt gtagagtgtt atgtctctct atccagtgaa gtttaatagc
      181 tcaagaaaat gcactattta tgatgattat tttgttttat ttccaatttt ggaaataact
      241 attctaatta aatctaaaat tataccataa ataagaaaag aaagtataga tgctatgtac
      301 caataaatcg aaattgaccc tgtaattgtt ctacatggga tttgcatacc tgaatccata
      361 aaaacaaaaa aactatcaac tctggaaata atagacaaaa taggatttaa acctattaga
      421 acaatacttt ttgagtcttg accaatttga tgcatataaa tctcaaataa tgcaattaaa
      481 aaaaaccaaa atgtaaaaga tttaataatt tttttcatca aaatacctca cctaatataa
      541 attctgtttg cactatttgc ttactacaac tatttatctc cattcagtca catcacttag
      601 ttgtaatcta ggtcttcttg atggttcttc atcaggataa cccaaagata ttgctgccac
      661 taattgacta tctgtattta accattcaca taattcacga tatgcaaagt atacatcaca
      721 aatccaaaga ctacctagac ctaattccac agctgtaagc gacatattct gaattgcagc
      781 tccaattgat tgcatgtttg ccatttcata gaatcgttct tcaggggata gcttttctaa
      841 aggtgattta cctaatatat ttaaaataaa aattgttact ggagcttgtt tcatgatttc
      901 aactgtgtaa tttgcaccag cgatatgttg acgacttcct ggaagaagcc cattatcatt
      961 aatttcattt tgaatacctt ttctcatggc tttaagcata gattcttttt ccttttcagt
     1021 gatgacaaca aaacgccatg gttgcctgtt tttagatgaa ggtgcattta ttccagcttc
     1081 aattattttc tctatagttt catgtgaaat gctttgattt ttatattttc tgatacttcg
     1141 tctttttgat atagaatcac ttatcatttt aagtaacctc cgtttatttt ttggaaaaat
     1201 ctatttattt tctattttaa ttattttagc attaatcaga aaaaaagtca ttgattttag
     1261 tatacaatta ttaatgatta tattaagaat tgtatcaaaa agtatgtgat tatactaagg
     1321 gattatatta aacattatat ttaaaattgt atgaaaggtt gtatttaata ttatattgag
     1381 agatatatat attaggattt atatatatta agatttatta ttatattgag ccttatatta
     1441 aattaaggac tataatttga aaataagcta taaaaactta atattgtttt gttcaaagat
     1501 aaaaaaagaa tactttaggt gatttttatt aaaaattaag agtgataaga ttatatactt
     1561 tataaatgta aatatgacgg ataaaaatga taaatataat aatatatata tttacattag
     1621 gagttttcta tactataatt atttaaaact aaatataaat gctggaatta tttaggactt
     1681 gaaattgtct aaaaataaat ataagtgatg aagaggtgat gtgatgagat tagatatgga
     1741 tagtatgtta tatgtactaa tttatatgac attattggta tctatcattg gaagtatatt
     1801 ttatttttgt aaagacctct taaatcataa aattaagtat gttttaataa gagacatatt
     1861 tgtaaataga attacatatt ctgaagaacg actgcctaaa cagtatatag tttttcagaa
     1921 atatgatatt tggaggtatt gtagtttgtt ttaatttgaa atgaatctat tataaattct
     1981 aaagtttaaa aataaaaagg agagaataaa atggatttca tttcaagtat attgcaagga
     2041 ttattaagta tattatttaa ttttacaggt gattttggaa tttctattgt acttataact
     2101 ttaatagtta aattagtact tatgccacta tcattaaaac aaagattttc tgtaaaaaaa
     2161 cagcaagaat tagctgaaaa aatggaatat ataaaagaaa agtataagaa tgatactaaa
     2221 gaattggaaa agcaaataca agtaagttct gtagaaagta tgaagagtat gctgggatgt
     2281 cttatagttt tggttcaaat gccagtagta tatgctttat atcatgtatg tttagatatg
     2341 acaaaggaat ttacaacaat tataattcca tggattgcta atttaggtac atttgataat
     2401 ttgtttatat taccttgtat atatacatta attatgttag cttcaaattt agtgaattat
     2461 ataccatatt taaaaataaa ttctcaagta aagtttaaca aacaaatggc tgtggtgact
     2521 accataacaa gtcttatact aactgttaga actccagtag ccataggtct gtactttata
     2581 acaagtgcaa tttattcatt aattgaagat atttgtttta gaatatattt taatcgaaaa
     2641 aatagaatag tgacaaaata atataattat tattagaaat attttagcct gctaacatag
     2701 aaaaagttag taggctattt ttatctatga tatcaattcc attaagaata gtctaaaaaa
     2761 tactatcaaa atgctataaa aaatactatc aaaatactat aaaaaaatag ttgaaaaata
     2821 aataaattaa tataaactaa aataaagcct acaaaaaaga ggtgataaat agaaatggct
     2881 aaaatactaa ttgtagaaga tgaaaaaagg atgcaaagta ttattgtaga atatatgcaa
     2941 aagggaggat atacttgtat aactgctgat gatggagttg aggcacttac aatattaaag
     3001 agcaacaata tagatttaat gatattggat attatgatgc cgtatttaga tggattttca
     3061 gtgtgtagag tttcacgtga aatgactaat atacctatta ttatattgac agctaaaggt
     3121 gaagaggagg acaaattaaa gggttatgaa tatggcgcag atgattatat aacaaaacca
     3181 tttagcccca aagtactttt agcaaaagtt aatgccttgt tacgtagata cactactgat
     3241 attcccaaaa attcattgag tttaggaaag atttttatta tggtagcatc aaggcaagtg
     3301 tatgtagaag ataaattgat tgatttaaca tataaagaat ttgaattatt gcgtttattt
     3361 atggaaaacc ctaatcaagt tttttccaga gagaaacttt taaattgtat atggggatat
     3421 gattttgaag gaaacacaag aactgtagat acacatataa aaaccttacg caaaaagctt
     3481 ggtagtgaag gacaccatat agttacatta attcgttcag gatataagtt tgaggttaag
     3541 gaatgaatag tttaagaaag attatagaaa aactgaaaaa tgtagatatt tcaaattgga
     3601 ttaaacaaaa ttttggacta tattcagtta gaaaaaaagt gtttttactt tctaaattat
     3661 caggagcgtt aattatatta ttttatctgg ttgttgaaga attttcgata aactctaaat
     3721 ttgaattttg gatttggttt ataatactgg ttatatttat tatgagtatt gatttcttat
     3781 tgggaaaatt tatttcagaa ccaatcacat ctataaataa atctgcaaaa agtatgtccc
     3841 aacttgattt ttctaatcca tgtactgtaa atactaatga tgaatttgga gaactttcta
     3901 ggagcctgaa tacaatgtct acaaatctac aacaggcatt atcagaccta gaaagtgcaa
     3961 atattcaact tgaaaaggat gtaaataagg aaagaatgct attggaacaa agaaaggagt
     4021 tggtagatac aatttcacat gaaatgaaga ctccacttgg cattatacgt gcgtatacag
     4081 aggggcttat ggatgaagtt gatgaagaaa aaaagaaaaa ttatatgaat gttataatag
     4141 aagaaactga tagaatgaac aatatgattg tatcattatt agacttatct gcattggaag
     4201 caggagtttc taaacttaac ccagagcgtt ttgattttat agagtttgtt gaaactgtgg
     4261 caggtcgtct tttaattgat ataccagatg ccaattttta ttttacatat gatttgccag
     4321 agtatgaagt ttttgtagtg gcagataaaa tgagaatgga acaagtagta gagaatctag
     4381 ttattaatgc aaagaagcat gttgtatata atggtaattt agatttatcg attacatgtg
     4441 aaaatggctt gcttttattt gaaatttata atgatggtag gtttatagag caagatgaga
     4501 tttcaaagat ttggtctaag ttttatcgta gtgttcaatc tcagcgtaca ggaggttcag
     4561 gtctagggct tgcaattgtt tcacaaatac ttacaatgca agggttagaa tatggagtga
     4621 ataatcgtga tagaggagta gagttttatt ttatgattcc aattgatgaa taatttagta
     4681 ttaatttata aatcataagt atctgatgta aaatattttt atttgtatat gtaagcactt
     4741 aaagagaata aaataaaaaa acttaatgaa aaagtctaat aaaaagttta ataaaaagct
     4801 taatgaaaag cttaataaaa agtcttgttt tcctgatgaa aacaagattt tttattaagc
     4861 tttttattat ttcacttcga tttcacaaga gagacactct gatttcacca aatagaaata
     4921 aaataggtta aataaattaa aaaatagaag cgtaattaaa taaggttaca agggggagta
     4981 cttatgaaat ggtatacatg gttgactatt atattgataa tattgctttc tattccgctt
     5041 aaaattaaat ttataaaatg gtgggataga cgacaaaaaa atgataaagg aggttatgat
     5101 agatgataaa agtaggagag ttaaaatttt cttatggaaa agataaacag atattgcatg
     5161 gacttaattt tgaagtaaaa gaaggagaaa tctttggatt ccttggacct aatggttcag
     5221 gaaaatctac aacacagaaa atcttaaatg gtgttttaaa aggctacaat gggcacgtat
     5281 ccatttttgg gaaggaagtt aaagcatata cagagtctct atatcaaaag attggtgttt
     5341 tatttgaatt tccttattta tataccaatt taagtgcaat tgataattta gaatattttt
     5401 cgtcttttta tcctaaaaat caaaggagag acatatatga actcttagat ttgttagagt
     5461 ttaagaaaga gtttataaat aagcctgtat catcctactc aaaaggtatg aagcaacgta
     5521 ttagcatggc aagagcattg gtaagtaatc caaagttgtt atttttagat gagcctacta
     5581 gtggacttga cccatctgga gctgtactat ttcgtaagat tattgaagaa gaacgaaaaa
     5641 aaggaacaac tatctttttg actactcata atatgctaga tgcagattta atgtgtaaca
     5701 atgtggcttt tattgcagat ggaaagatta tggtaataga taaacccaaa aatttaaaaa
     5761 tgaaaaatag caataataaa gttgaagtgg aatttgtata taatggaaat cgagatattg
     5821 aaattgtaga tatacaagag ttagaatctg gaataacttt taaatatgat gaaatcttaa
     5881 gtgtacattc aaaagaacct acactagaag aagtttttat taaatacaca ggaaggatgt
     5941 tagtgtaatg tattctaaat tttttacctt agtaaaaaaa gatttttgga tgatgattta
     6001 tggtaaattt tttgtgctga cacttggctc tctcatactt tattcgtgtt atattaattt
     6061 tggttatgta aagtttatgg atgaagatag ttatcacaat aatgtatatc tatataatcc
     6121 agagaatata agcatgagtg catctccatt aattaatcaa gtttcttcta taggtgaatt
     6181 aaaagcaaaa cttgatgaag atacaagtgc agtttgtatt gatatgagtt ccagtaagcc
     6241 gaaagtaatt ttacatgaaa gtattaaagg agttgacaat tatagagctg actatgcatt
     6301 gtcattatta tcatcagaaa aagaccataa tagcaaaata tcagacaaca atgcaataat
     6361 tcaaattaat gataaggata catctgagat aaaacaaaga aaagacatga cttgtgagat
     6421 tttattcttt gaaattgtag ctattggatt tttagggatt gcctctttat tatttaaaga
     6481 aaagcagatg ggagtaatgc gtattactgg tattttacct gtaaaaagaa gtctttttat
     6541 attatcaaag atatttgctt tttttatatg tgacctatgt tttacagttc ttttagtagt
     6601 atttaatatt ggatttttag aaggaataaa aatacttcca caagtattag ttcaagctag
     6661 tattttatca attattatgt ctttgattgg aataggatgc tcaatgttat tgagagattt
     6721 taagcaattt tctcttatat atcttgtggt tgctgtattc ataactacac ctatatttct
     6781 atctgcaaat acatcttttg aaatagattg gattaaatac catcccttct atcatgttta
     6841 tagtcagctt aaaaatgcgt ttttcatgaa tttttcaaaa gaattagttt attttgtagt
     6901 gtgttctttg acaataatag ttttattttt acttgtaaaa tatattttta ataaagaatt
     6961 ggttagggag ggataatctt gataggatta cgttaccagt taaagagtat aaaaaaagat
     7021 aaaatgtgta taatttcctt ctttttacca gttgttatgg cgattttaat aaattttatg
     7081 ggaacaattg atatatcttc attaggagag atacgttttg gtatagtgaa ggatacactt
     7141 cctgtacaaa cagagcagtg gttgaagaag tatggtatgg taagtgtata tgacacaaaa
     7201 atgcatttaa tacgtgaaat taaggatatt aaaacggaca caattggagt tgttagagat
     7261 ggtaaaggaa taaaaactgt gctttatgga aatgagatta atgctataaa aaatgttgga
     7321 aagacattgc cagagatgtt tagactaaag ggtgatttaa aagatgttga ggttacaata
     7381 ttgcctaaag atagtatttt aaaagagttt caaaatgttt ttattgctat gattttaatt
     7441 actgctatgt ttatgggatg cacctttaat gcaatgaata ttatatctga aaaagaagat
     7501 ggaatatcat ttataaatga agttttgcca cagagtagaa gtcagtatat tatacaaaaa
     7561 gtatttttgg gtcttttatg tgggtgttta tcttcaatga taactgtatt tatatgtttg
     7621 gatatttcaa tattagatat gataatgatg ttgttactcg ttgtattttc agcatttatt
     7681 tcatcactta taggtttatt tattggaaag ttgtcagaag gtcttatggt aggaattgtt
     7741 tatattaaaa tagtaatgat tttatttata ggtactcctt tgttaatata tcttctaggg
     7801 gttaatacca gcggtatagg gaatttatgc tatataatgc catcagttgc tacatttaat
     7861 ggtattatgg agattattaa tggtaatgtc attattataa aagatattgt aattttggct
     7921 gtacattgtg tagtatggtt tatgatatat attattttag ataaaaaaag aaagttatct
     7981 tttagtagat aactcagtat aattataatt ggggaaattt aataggtgat ttaatatact
     8041 ttgtatagtg taatttatgt agtgcaattt gtatacttta atttatgtag tgtaatagtt
     8101 agttttattt tataattatt caatataatt tagtaagaag ttcagtacaa ttagagctac
     8161 ttagtggaaa acttaatagg tacttaaact atataaatac tttattttcc tccatttgta
     8221 ctataaattt aatttatgat ataaatggag gtattattat atgatttgat aaatttcatc
     8281 attataacct acaagtaaag gtattattat ataaaattaa taaagatagt atcaaaatat
     8341 tatttgctat aaagagaggg actcaaaata aagataaacc tatttttcaa tgttgaaatg
     8401 ataaaatata tttgatttca tataaaaaat tttcttcata aattaaaaag tccattttaa
     8461 gtcccctcat ttttaaccag ataaatcgag ttaaactatt taaatatatt actcggattc
     8521 atttgactta gatattcctt gcttgtaaaa ttgttttgaa taggggatag ccaaagcaaa
     8581 aaataaaagt ataatccctg ctatgattat taaattatta atagaaatta catctgccat
     8641 tggtccgaaa atcatcatac caagaggaat aaaaccagta tatataataa taggtaagct
     8701 aagaactcga cctagcattt gtggtgctac atgctcttgc aacatagtca tagctgatgc
     8761 ttgaatgatt ggaattgaaa aattcgtaaa aaacataaat ataaaaaatt gccaagcttg
     8821 tgttacaaga cctagaataa ttgaaaaaat agcataggat aatattgcta gaaaaaaggt
     8881 cttatttcta tttttaaaac caccaaaaac tcctataatc aatccaccta aaaccatacc
     8941 taaaaatcca atcatttcaa taatagacag gtatatataa cccttgccaa atgttcgttc
     9001 aataagaagt cctataagaa atcctgatgg aacacaaaga agcatgaatg ctccataagt
     9061 aaaaagcact tttctaatga acttatctga aaaacagtac tttatccctg ataccatatc
     9121 tgcaaaaaat gagacttttt cagtttgttt tggtatatca tgtttaggaa ttttgatgaa
     9181 tatcaataat acaatagcaa taattgcagt aaatacatca attaaaagaa cttgatttat
     9241 tttattacca aatccaagta ttgcagcagc tacaatagga actataaatt gtactataga
     9301 ttgtaggcta ctatttatac cattaaaacg cattaaatgt tcttctggta caagttgagg
     9361 aatcattgcg tttacagcag gtgtttgtac accacttcct agtgaacgta taacagatat
     9421 tactgatatg gctattaatt cacttgttgt gccatttgat gacatcataa atagaattag
     9481 aactaatgta gatatagcaa ttgttgaatc tgatacaatt atgagtacct ttcgattgta
     9541 gtagtctgcc catacaccag caaaaaaaga aattatcatt tgaggtataa aggagcatac
     9601 agttaaaact gttacccata cacctgatga tgtctgaagt gtgacatacc atatcattgc
     9661 catttgtaca agtgatgagc caaataagga aatatattga cttgctaaaa aaagaatgac
     9721 ttttttcttc catgtagaat tagtattttt gttttccatc ctattcctcc tttgatttgt
     9781 gtgttgaatt tttcttgctc ttaaggataa cacacaaatc aaagtctgga gttagagtgg
     9841 agggctagga aaattgtttt ttcataattt gaagatgaga tttcatggtt tttgcattat
     9901 gttcagcttc tttcaatgaa gttatcagtt tgtcacacac tgagataatt tcgtcatcat
     9961 cttttggagt gtcaaggaca gttttaatat tagtattagg attagaagat aaagcattta
    10021 acattcgtaa aatagctgaa agagaataat ttgcacaacg aagtgcgctt ataattttaa
    10081 gtcgttttat atcttcatca gtatatacac gataaccatt ttgttttctt tttactttta
    10141 acaaaccatt catttcccaa tttcttaaag tatctattgt aacatttaag tgttctgcag
    10201 tttcttttct agttaaaaag agtttatttg tttctggagt atttccattt aaaatctgtg
    10261 caacaatagt aagtgcttcc tcggcattag atttttctat ttctaattgt tgcaagtatt
    10321 gatttacaag actaatagcc ttatcaaagt ccctattcgc tgatgttctt acaatctcaa
    10381 gggcatcttt tcttaatccc ctttgtacca cttcaatttt caaggctgta cgagcaaatc
    10441 taaattgttc tatatgaaaa tcattaaaga tacgataacc attggtatta cgcttaggtt
    10501 taggtattaa gtttagttct tcatataaac gtactgtatt aggatgtaca ccaattaaat
    10561 ctgctacctc tgatgtcgtg taagtgtcca ttagtattca actcctttta gatatatagt
    10621 attagtcata ataacaccaa acaaaagtct ggtgttataa tggagggttt ggttatctaa
    10681 gagtaattag tttatgaaag agtaattagt ttatgaaaga gtaattagtt tatgaaagag
    10741 taattaattt atgaaagagt aattaatcta ttatagaagt aagtatatat ttttcaataa
    10801 actcccatct atcacgaggt ttaaacacta ttttagatgg tatggctatt actaagtcat
    10861 attgtggaat acaacaaata gcatttcctc cagttcccat tgctgaatac cacaaaacac
    10921 catctttttt acatagccac cacagataac cgtattcatt actattcatt ttaactgatt
    10981 cttcaatcca cgatttagat ataatacgtt tattattcca aataccatca tttaaataca
    11041 gaaaaccaaa tcgcaacata tctctagcac tcaatgtaag tccccagcca cctatagaat
    11101 aaccctgtct atcttttgcc caacccttaa gattttttcc aaagaaatct tcaaaaccaa
    11161 aatctttcat atcataatct ggtataactt tcataccaat aggtttaaat aagtattcat
    11221 tagcaaattc acgagcagat tttccagtag tttttgttat aatagctgaa agtaggtgcg
    11281 ttccagctga agaatatttg aaagtaccaa tttcgccttt ttgaccaagt tgattcaagg
    11341 tatattttat ccaatctttt tgtttgcaaa gtctttctaa agactcagtc atatttttaa
    11401 aagggtatgg tgcagtcatt gtaagtaggt gacgtatagt tactgctttt ttacatattt
    11461 cagaaggact acaagtatat tcagggaaaa aatcaacaac cttttggtca acatctttta
    11521 tatatccttt atctattgca atacctatta aggctgatat aatacttttt gtaactgatg
    11581 caacatgaaa agtattatca gcattatatc cattatagta cttttcaaag acaacttttc
    11641 cttttcttgc aataattatt ccatttatat tactatattg tgagattatt aaaggttcaa
    11701 gttgtgagag cttttctgaa ctcatgccaa cacttgaagg gtctactttt tcaaatatta
    11761 aatctaagca attgttttta ttcattaaag atacctccct gttatagatt ttggattttc
    11821 ttttagagtt tttggagaac cttctgcaat tatataacct cctttgtcac caccttctgg
    11881 accaagctca acaatccagt cacaaacatt taatacatct atatcatgtt caacaacaat
    11941 tacagaattt ccattttcaa ccaattcatc taataattga atcaacttag aagtatcgta
    12001 tagacttaga ccagtagttg gctcatccaa tacataaagg atattaccat ttcgtttttt
    12061 accaatttct tttgcaagtt tgattctttg agattcacca ccacttaaag ttggtgtagg
    12121 ttggcctaat tttatatacc ccatacctat ttgttctaat acatttaagt gtgaaacaat
    12181 gtttggaata tctttgaaga aatgtacaga ttcagaaaca ctcatattta aaatatcatg
    12241 tatattttta tttttatatt taatagataa agattcatca ttaaatcttt ttccctgaca
    12301 ttcactgcat atatggtcta tacttagatt atttcccaac cagacctttt catatccact
    12361 accactacat ttaggacaag cccctttgga gttaaatgag aaatgaccag ctgtaaatcc
    12421 tcgttctaac gattctggct gacctgcaaa tagtgtacgt atcttatccc atataccaat
    12481 ataagaagca ggagttgagt tcatattttt gccaatagga gattgagata tctctgaata
    12541 tccagaaata tgtttagtac caatcagtct atctgcaata gtttcaacaa ctgcataatc
    12601 gtcttcctca cctatttcac tctctgaaga atttgtttga ttattgatag tatggttatt
    12661 aaattggctt ctaagaagag gaagtagggt gtctgatata agtgaactct tgccactacc
    12721 tgattttcca gatattccaa ccatagcacc caaaggtaat gatacagtta catttttaag
    12781 attatttgta tttgcatttt gaatagttat acaaggtatt ttatcagtat gtgtaatgtt
    12841 tttattgctt gttctattag gcattggata ttttccagat agatactgtc cagtaagtga
    12901 tttgtcggat tgaagtagac cttctaaatc tccttgatat actaattgac caccttcaac
    12961 accagctttt ggaccaatat caataatatg ttctgccatt ttaattgtgt ttttatcatg
    13021 ctcaactact atgaccgtat tgcctaaatc tttaagtttc tttattgatt ttaagatgtc
    13081 tattttttct gattcatgca atccagctgt tggttcatca agcacataaa ttaatgagtc
    13141 catctctgaa tcgaggtgtg aatttaaaaa tagtctttgc atttccccac cactcaaagt
    13201 tgacatttct cggtataagg atagatgacc taatcgtgat tctattaaat gttgagtttt
    13261 ggataaaata tcatttacga gatttgtacc aaatgtgttt aaattacctt gatttattaa
    13321 gagtttaagg aaatcatcaa tttctaaaat cgtcattttt ccaagttctc caatatgttt
    13381 tccgtttaaa agtactctac gtgcttcttc accaatttta aaaccattgc aatctgaaca
    13441 ggcagtcata gtataaactc catttaaatc ttcgcccctt ttgtaacgat tgtgaaatac
    13501 ctttgataaa gaggaacttt ttttaccatt ttcataatga ccatagagta cttcatttct
    13561 tatttcttca ggtagttgta agaattgtat gtctaaataa tcgttgaatt ttttagaaaa
    13621 tactctcaaa tatcctggtg taatctttgc tctatctaag acttgtttta gggtgtcatg
    13681 cttatcaagg actaattttt caatattaat ctcaaaatat gcaccatgtc cagagcactt
    13741 catacacatt ccatctgaag agttgtatga gaaataactt ggtcttaatc gttcttcctc
    13801 atatccacaa ttattgcaaa ttagattatc gcttacagga gtatcacaca tagtacacat
    13861 tatttgacct tccactgaat acaatagtgt aagcatgttg agaatattgg ttcttgtgcc
    13921 tactgttgaa cgaggattgc tctggcgaat aatattttgt tgaacagcta tagtgggagc
    13981 taaaccttga atattatcaa acttatcttc actatcaata cctgcaagta tacctaaaga
    14041 ttgcagatat tgtttacgcc cttcctcaaa tacaatgtca aacataaggc tagacttacc
    14101 tgagccactg acacctgttg caacaacaag cttatctttg gggatagaaa catctatatt
    14161 tttaagattg tgtatctttg ctccattaat ttttatttct ttcattggtt cacctcattt
    14221 tatcaatttt atcaaaccgt aaaataggga tatattaatc cttaatacaa gaatagatta
    14281 ggtgaggtta ttaaaaaggt tctataggta aatatatatc gaccaagtgt ctattttgag
    14341 ggtgattgtg tgggttgtta agatatactt caaaagggaa ggaggcacgt agcttataat
    14401 taccatttga tagccattca ttatacataa aatcccacgc atcactatat tcagattttg
    14461 aaatatcaaa atgtcccaca agatattttc cagaaggtat tatcatattg ccaagattgt
    14521 cattctcttt gacaactatg ttatctggaa tagtcatgca aatactagtc cttaattgat
    14581 gctcctgtgt aaattgtgga ttatcatgat aaatggctaa tatttgtgta ttttcaagtc
    14641 caagtagatt ctgctcactt gcatatgtga ataaccgttc taaaagtttt gggaaagtac
    14701 tggttagatt accatatgaa ccagtatacc tagtgtaaat agtattcata ttatcaagtt
    14761 ctagaatttc aatttcacct ttaacctctc tagtattctt acatttaggt tttgatatgc
    14821 ttctattgta ctgagaaatt ttatatggtt ctttgcaatt cttgctataa ttgtttctat
    14881 attttatagg gcttatttta tagtaatttt taaatgctct cgagaaaact gctgaatcag
    14941 taaagccaaa gtagtgtgca atatcagtaa cagtcatgtc agttctatga ataagaaaag
    15001 cagttgcatt ttctagtttt agcctattta catattgtgc caaagtttct ttttctattg
    15061 ctttgaagat tctatgaaaa tgaaattttg aaaaacctgc tatattagaa agttcatcaa
    15121 gagaaagagg ttcatgtaaa tgttcttcta tatagtcttg cactttgcaa atacgattta
    15181 gatattcttt tttactttta gcatttgtca tatatagccc tccttattgt gtaaaatgtg
    15241 tatcaattaa tttatagcaa tatagtaata aaattttatg tttttgtaat ttatgataaa
    15301 taagatagcg tttaattttt tataattgat aaaagatatt tataattaat aaaagatata
    15361 agatgcctta tatttgtctt tgcatataag tatagtcttc gtaataatta gtataccata
    15421 gtgatttatt tttaattgtg tatttatata aatacacaac ttatgatatg gacgaattat
    15481 tatgcaaata agctgtaatt aaataaattg caatataaac cagttgaaac ataagttagg
    15541 gaaatattat caaagttatt atttaacata agagtataga tggaataaaa taagattaaa
    15601 aaattacata ctaaatttaa taaaattttt atattaaaaa taatattaag tttatt
//
LOCUS       DAEORM030000077        15606 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.080, whole genome shotgun sequence.
ACCESSION   DAEORM030000077 DAEORM030000000
VERSION     DAEORM030000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15606)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15606)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 15606)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15606
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.080"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            complement(60..1382)
                     /locus_tag="KRH23_003341"
     CDS             complement(60..1382)
                     /locus_tag="KRH23_003341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54-dependent transcriptional regulator"
                     /protein_id="HHS5226613.1"
                     /translation="MKILLVDDELEYGVVMKKILQKKGYLVDIALSGEEAINIIKKDK
                     NYDLVLSDVMMKNMDGVQLLDRIKSINRDIEVILVTGYGSIENAVDAMKRGALSYFIK
                     SNPIENLLEEVEKVKASKISVSVQKNNFEFTLESKNRDFNNIIKIAKKAACKDVNILI
                     LGESGVGKDILARYIHSISPRKNEIFVPVNCCSFSENLLESELFGHEKGSFTGAVDSR
                     KGRFELSNKGTLFLDEIGDIPLNVQVKLLRTLEDKSIERIGSNKSIKVDFRLICAMNK
                     EPKVEISNGNIREDFFYRISTITITIPPLRKRREDLTTLIEFFLNKYQIEHDKKIHSI
                     DKEVKDFLLNYNYPGNIRELKNIINRLVVLSEEGNLSKDNLNLISNNVYIDDEISIRP
                     LREIRKEFECEYIEKVLSLCGNNISNTAKKLEISRRQLTNKISEYNIK"
     gene            complement(1382..3376)
                     /locus_tag="KRH23_003342"
     CDS             complement(1382..3376)
                     /locus_tag="KRH23_003342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HHS5226614.1"
                     /translation="MNKKKIVIIGIIYSFLVVFSLTNMYVNMEYNLNVFEYIKKSLPF
                     TEEEKKWLEKHKNLIYSSDQSSPPLRYKGKEDGQYKGIIVDLINSLSIQIGRDFYFKP
                     NNWWKESFVNSIDDSIKFFDLIPSKERANKFIFTDPIYTLSANILKDKKSQDINSYMD
                     LKGKTVAIPEGDYSINFLKQKIQDINILLTPDIKTGVNHLMSGKVDAVVGDEPVLRYY
                     INNYGLSNKYSVLSNPIYTKKAVLAVPKQYEELVSILNKGIFKLQKNGVYKDLKKKWY
                     STYNEVDDILYERGIVPSIYLFIGIILISIYVFYSYTYLLKIEIKRKTEQVIENKKTL
                     EATFNSITDIIMLVDENNNIVESNKVLYDFMGEMSYKIADLISMIKGVIENTFSENTN
                     KTSEIEIHNKILKINTFPVEYKKNNTEYIVVLIKDITNDKIVEAKLLRENKMISIGQL
                     ASGVAHEIRNPLGIIRNNCYLLKDNVTMEEVNDCVKSIESNVDRASNIITNLLNFARI
                     SDDNLEHINIKNFIENIVKLQYKMLQLKNVEIKIDCEHNLICYINGESLKHVFINLIS
                     NSIDAIHQDGKIIIYCYEKNHCLFIDFKDNGEGIKEDVLKDIFNPFYTTKPIGEGTGL
                     GLYITYNEIKKNNGDISVESKLGVGTCFHIKIPLNKEVTI"
     gene            complement(3463..4710)
                     /locus_tag="KRH23_003343"
     CDS             complement(3463..4710)
                     /locus_tag="KRH23_003343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HHS5226615.1"
                     /translation="MQITTFGAIFGLLIAIILIIKKFQAVYSLMLGAFIGGLVGGANI
                     TQTVDFMANGAMNISPSILRALASGVLAGSLIKTGAVDKISEQIVKIFGEKRALFSIA
                     ISTMVLAGVGVNLDVSIITVAPIGLYIGRKLNYSKLSILLAMLGGGKAGNIISPNPNT
                     IAVADNFSVNLSSVMMANIIPAIIGVVITVILASILINKGNKVQSYEILEQREDLPSL
                     FKSLCGPIIAIFLLFLGNVSPIVIDPMIALPIGGIVTLIVTGNLNNSREYLAFGLSKM
                     QGVCILLLGTGTIAGIIQMSELQQSTIGALQFLNMPQFLLAPVSGILMSLATASSTAG
                     ATIASSTFHDAIINGGLSPISGASIVNAGSSVFEQLPHGSLFHTSAGSINMDIGERFK
                     LIPYEALIGIVMTIISTSIQLVL"
     gene            4938..5483
                     /locus_tag="KRH23_003344"
     CDS             4938..5483
                     /locus_tag="KRH23_003344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHS5226616.1"
                     /translation="MNDLNLGEKIAEVRKKQNLSIRDLAKLADVTPSLLSQIERGLAN
                     PSVNSLKSIASSLNVPLFTFFVSEVDKKNLIVRHDNRKKVILPGSKEVIYEILIPDSS
                     GNLEFAIMDLAPNTSSCVDRITHNGDEIAYVLEGEVKLFMDDDEFTLSKGDSVKVPLG
                     TKHKWQNDSNSESKVIFAVIL"
     gene            5497..6183
                     /locus_tag="KRH23_003345"
     CDS             5497..6183
                     /locus_tag="KRH23_003345"
                     /EC_number="3.1.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008253 - 5'-nucleotidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HHS5226617.1"
                     /translation="MKTYKFIFFDADDTLFDFKKSESHAFKKLLSEFDLEFNFENYIE
                     SYRNISDKLWLDLEKNIITLNELKLLRFELFANKISLDVDSETLSKMYLNFLGECTFL
                     IPGAIDILQYLKKKYTIVIITNGISAVQKKRLENSKIKEYIDGMVVSEELKISKPNPE
                     IFKYALKKFNCHDKSSALMIGDSLTSDVLGGINSGIDTCWLNSNNSINYTNHIPTYEI
                     NTLIELKKLL"
     gene            complement(6307..6927)
                     /locus_tag="KRH23_003346"
     CDS             complement(6307..6927)
                     /locus_tag="KRH23_003346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226618.1"
                     /translation="MNYNSNKNKYLLKDINLDDIFIDKNIVLKFLGYGNRKAPDTISK
                     IVEREIRNINDILDIKIYISEVDINKTPKECKKAFAVLYTIGDKIDFKMNDYMENCNM
                     MAGIALDKIGIVCLDYINEKIKMYLKGKYDSLKISHEIYPGDKDFEVERQKDIYNYVK
                     NKYNSIEIEINDYHQLSPIKSVAMLILMGDEENLESRCSKCPRKCF"
     gene            complement(6917..7939)
                     /locus_tag="KRH23_003347"
     CDS             complement(6917..7939)
                     /locus_tag="KRH23_003347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004853 - uroporphyrinogen decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen decarboxylase family protein"
                     /protein_id="HHS5226619.1"
                     /translation="MFSDMTLLQYINSEDRGFFLPDMGTNGLFLINKKAYEVYDSVDL
                     QLELAKTMDKYFESDFIYSFCDGITFCETLGLDTLRPDYDFPSVLTHTITDRDKLRKL
                     DVPDPYTSGRMPLNIESLSVISKSIKKPLYESIQGPFTLAGQLAGATQLLRCIITDKK
                     FVEELLEFTTELVRRYAVAANKAGAKYISIAEPTSVTLSKDRFDEFIVKNLNKIYNEL
                     DCWKGMHICGDTRELLDNMLSCNIDAVSLDQILDYEEIAPMIPRDIVLIGNLDPIKLL
                     GRSKPDKIRRETLKLLKKMRGYDNFLCDFGCNCLNTTPVENLQAAIKAGRISYKELDR
                     IDIDEL"
     gene            complement(7940..8578)
                     /locus_tag="KRH23_003348"
     CDS             complement(7940..8578)
                     /locus_tag="KRH23_003348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0031419 - cobalamin binding [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin B12-binding domain-containing protein"
                     /protein_id="HHS5226620.1"
                     /translation="MDILDDIAECILNMGVDNIENLVKIAIDKNIDVEDIYEYGLNKG
                     MIGALDKFENKEYYLSEVIVCTDALNKGINLLKGTGKVKKKSKGVILMSVVEGDTHEI
                     GKNIVKVMVEATGYKVIDLGVNRKSEDIIEEAIKNNVDIIGLSSMMTTTMENMKSVID
                     ELNMIEIDKRPKVIIGGGPVSMEFAEEIGADGYSSNAPKAVKLINKLIGGEV"
     gene            complement(8696..9847)
                     /locus_tag="KRH23_003349"
     CDS             complement(8696..9847)
                     /locus_tag="KRH23_003349"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004452985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HHS5226621.1"
                     /translation="MELRPRSAKLEEFDKVIELINYVFRISRNHKPTMMEEFPLLLSK
                     NNIENMIIISEDDKVVSDVNYLIQDVSIQGNRLKVAAIGGVCTHPDYEKRGYSSKILD
                     KVEEKMFYDGVDIVIISGTRSLYSRRNCSLVKSFYKYTIKPEDVKIAYEIVEFDETNF
                     EKDNDLDKMIELYNQNSTRFIRTRDEFQKLLHAATIAWGPIGYKKVFIKENNNIIGYL
                     IIRTIKKEDSTVGEVAEIGLNSVNVENILKYVANKFGLESLNYKVHVKNLKDQLKCNG
                     TKSLDYQQGTMKIINFTKLCDSLRSYFSQYADFELLKYMEFKQVENKYIIKYKEEELV
                     IENLDKLNKLFFEKNEEQYNEFKHLKNIYEFATKAFPVDFPWTANLNYQ"
     gene            10269..11081
                     /locus_tag="KRH23_003350"
     CDS             10269..11081
                     /locus_tag="KRH23_003350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0140663 - ATP-dependent FeS chaperone
                     activity [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Mrp/NBP35 family ATP-binding protein"
                     /protein_id="HHS5226622.1"
                     /translation="MADCNSCPSKGNCNSQSNCSIENNPNNKFGKIIGVMSGKGGVGK
                     STVTALLANKLNKMGYKVGILDSDITGPSIPRLMGVKNVKAYSDGSYIYPVENSNNIK
                     VMSINLMIDDENEPVVWRGPLLGGVVKQFYTDVLWEELDYLLIDMPPGTGDVALTVMQ
                     SIPISGIVMVSVPQDLVSMIVSKAVNMAKKMNINVLGVIENMSYIQCPDCSKKIKLFE
                     GESTEKFLDDLDLELLGELPMTKEIIDITHNGVTEISDDLDSILTNVVEKIK"
     gene            complement(11170..11361)
                     /locus_tag="KRH23_003351"
     CDS             complement(11170..11361)
                     /locus_tag="KRH23_003351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226623.1"
                     /translation="MERLMELIERKFLKDVELLELEDIENVIECKMTQPYNAHYNEYL
                     VKVKNGDEVEEYFVYLKHR"
     gene            11632..11871
                     /locus_tag="KRH23_003352"
     CDS             11632..11871
                     /locus_tag="KRH23_003352"
                     /inference="COORDINATES: protein motif:HMM:NF024242.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHS5226624.1"
                     /translation="MNYNLIKVIFSLFKKKSGYTFTNFLNKVRVEKSKKYILKKNLSI
                     LDVAVLIGFNSQNYYSIIFKKFNNFTPIEYKNIYN"
     gene            12180..13799
                     /locus_tag="KRH23_003353"
     CDS             12180..13799
                     /locus_tag="KRH23_003353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0005436 - sodium:phosphate symporter
                     activity [Evidence IEA];
                     GO_process: GO:0044341 - sodium-dependent phosphate
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HHS5226625.1"
                     /translation="MNIVISLIGGLGLFLYGMSLMGEGLQKSAGDKLKKIIELLTSNV
                     VMGVLVGTVVTGIIQSSSATTVMVVGFVNAGIMNLSQAIGVIMGANIGTTVTAQLVSF
                     NLEGIAPIALGIGILFYLFTSNQKTKHLSEILIGFGILFTGMEFMKDAVAPLAEYKAF
                     TDALLYFSKNPVLGILAGFAITGIVQSSSASMGMLIALASQGILPLSSALPILYGDNI
                     GTCVTSLLSSVGASRNARRAAVMHLSFNVIGTIIFMLVLNKPISAIVTHFDPTDTARQ
                     IANAHTLFNLTNVIILLPFSKYIVKLANRLIPIKETESEIVNNTKYLDERMFSTPSIA
                     LGNTVQEVVRMGHKATNSLEHSIAGFLNKSNEDINKAFESEKVVNKLQKDILNYLLKL
                     SKEPLRDDERFRTDLLFNTVNDIERVSDHAENIAELAMSVKEMNISFSDSAIREIYEI
                     YNKTITNFKDALIVLDVKDFELANKVLEVENEVNYLEKTFRNSHMIRLNNGSCTIDAG
                     VLYLDLLTNLERISDHSTNIVKQVLKLKQKI"
     gene            14173..14367
                     /locus_tag="KRH23_003354"
     CDS             14173..14367
                     /locus_tag="KRH23_003354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HHS5226626.1"
                     /translation="MINYMVEIIYSEKISEVENMLKIENIQYEFTSRDGFIFFGFYDM
                     TDAYRFETLCSDEKIRFKRI"
     gene            complement(14926..15249)
                     /locus_tag="KRH23_003355"
     CDS             complement(14926..15249)
                     /locus_tag="KRH23_003355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6054 family protein"
                     /protein_id="HHS5226627.1"
                     /translation="MATEIFTVKITPLEAQKMIKENLDADLVFSDSYNLGDDKFILIT
                     TFEKYYARNNSDAGLIVVYENTTGKTVIKATSTGSAIGILKIDWGAGGNLLKRVKNIL
                     TDYII"
     gene            complement(15294..15548)
                     /locus_tag="KRH23_003356"
     CDS             complement(15294..15548)
                     /locus_tag="KRH23_003356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226628.1"
                     /translation="MENKDFKLTICIFAFVIGVVVLFCCIGLGEFSAEHIIQQNGGIM
                     DTDQYNIYLDQSISQYRNFGSILALLGGIGILFDKYIRKY"
BASE COUNT         5367 a         2348 c         1700 g         6191 t
ORIGIN      
        1 tgtttatctt ttaatacagt ttgagaaatt tttttctcac ttaatgagaa gtttttttct
       61 cacttaatat tatactctga tattttattg gttaactgtc ttctactaat ctccaatttt
      121 ttagctgtat ttgaaatatt atttccacac aaagataaaa ctttttcaat atactcacat
      181 tcaaactctt ttcttatttc tcttaaaggt ctaatactta tttcatcatc tatgtataca
      241 ttatttgata ttaaatttaa attgtctttt gataaattgc cttcttcact taaaactaca
      301 agtctattta ttatattttt taattctctt atatttcctg gataattgta atttaataaa
      361 aaatccttta cttccttatc aatagagtgt atctttttat catgttcaat ttggtactta
      421 tttaagaaaa attctataag agtagttaag tcttctcttc tctttcttag tggtggtata
      481 gttattgtta ttgtacttat tctataaaaa aaatcttctc ttatatttcc atttgatatt
      541 tccacttttg gttctttatt catagcacaa attaacctaa agtcaacttt aatagattta
      601 ttacttccta tcctctctat agatttgtcc tcaagtgtcc tcaaaagttt tacctgaaca
      661 tttagaggta tatctcctat ttcatccaaa aatagagttc ctttattcga aagttcaaat
      721 ctaccttttc tactatctac tgctcctgta aaagaacctt tttcatgacc aaacagctca
      781 gactccaata gattttctga aaaagaacaa caatttacag gtacaaatat ctcattcttt
      841 cttggactta tgctatgtat atatctagct aatatatctt ttcctacacc agactccccc
      901 aagattaata tattaacatc tttacaagca gctttttttg ctatttttat gatattatta
      961 aaatctctat ttttagattc caaagtaaat tcaaaattat ttttttgtac agaaacagat
     1021 attttacttg cctttacctt ttcaacttct tctaataaat tttcaatggg attacttttt
     1081 ataaaataag ataaagctcc tcttttcata gcatcaactg cattttcaat acttccatat
     1141 cctgtaacta atataacctc tatatctcta ttaatagatt taattctatc taatagctgt
     1201 actccatcca tatttttcat cataacatca gataaaacca aatcataatt tttatctttt
     1261 ttaattatat ttatagcttc ttcaccactt agtgctatat ctacaagata gcccttcttt
     1321 tgtagaattt ttttcattac cactccatat tctagctcat catcaactaa tagtattttc
     1381 attatatagt cacctcttta tttaatggaa tttttatatg aaaacaagtt ccaaccccca
     1441 atttactttc aacacttata tctccattat tctttttaat ctcattataa gtaatatata
     1501 aacctaaacc agttccctca ccaattggtt ttgttgtata gaagggatta aatatgtcct
     1561 ttaggacatc ttcttttatt ccttcaccat tatctttaaa atctataaat aaacaatgat
     1621 ttttttcata acagtatata ataatttttc catcttgatg tattgcatct attgaattag
     1681 aaattaaatt tataaataca tgttttaacg attctccatt tatatagcat attaaattat
     1741 gttcacagtc aatttttatt tcaacattct ttaactgtaa cattttatat tgaagtttca
     1801 ctatattttc aataaaattt tttatattta tatgttctaa attatcatct gatattcttg
     1861 cgaaatttaa caagttggtt attatattac ttgccctatc tacattactt tctattgatt
     1921 taacacaatc atttacttct tccattgtaa cgttatcttt taagagatag caattatttc
     1981 ttattatacc caaaggattt cttatctcat gtgctacccc agaagctaat tgtcctatag
     2041 atatcatttt gttttctcta agtaatttcg cctctactat tttatcatta gttatatctt
     2101 taataagaac tactatatac tcagtattat tttttttata ctctacagga aaagtgttta
     2161 tctttaaaat tttattgtgt atttctattt cactagtttt attagtattt tcagagaagg
     2221 tattttcaat aacacctttt atcatgctaa tcaaatctgc tatcttataa ctcatttcac
     2281 ccataaagtc atatagtact ttgttcgatt ctactatatt gttattttca tctacaagca
     2341 ttattatatc tgtaatacta ttaaaagttg cctctaaagt ttttttattt tctattacct
     2401 gttctgtttt ccttttgatt tctatcttta acaaatatgt atagctataa aaaacataaa
     2461 ttgatattaa aattatacct ataaaaagat aaatactagg cacaattcct cgctcataca
     2521 atatatcatc aacttcatta tacgtagaat accatttttt ctttaaatct ttatacactc
     2581 catttttctg aagtttaaaa atgcctttat ttaaaatact aaccagctct tcatattgtt
     2641 taggtacagc aagaactgct tttttagtat atataggatt acttaaaaca ctgtatttat
     2701 ttgaaagtcc ataattattt atatagtatc gcaatactgg ttcatcacca acaactgcgt
     2761 ctacttttcc agacattaaa tggttgactc cagtctttat atctggagtc aacaaaatgt
     2821 ttatatcttg aattttttgc tttaaaaaat ttatagaata atcaccttct ggaattgcta
     2881 ctgttttccc ctttaaatcc atgtaactat ttatatcttg ggacttttta tctttcaata
     2941 tatttgcact caaagtatat attgggtcag taaatataaa tttatttgcc ctttcttttg
     3001 atggaatcaa gtcaaaaaac tttatactat catctattga atttacgaaa gattctttcc
     3061 accaattatt tggtttaaaa taaaaatctc taccaatttg aattgacaga gaatttatta
     3121 aatcaacaat aattccctta tactgtccat cttccttacc tttatatctc aaaggaggtg
     3181 aactttggtc agagctgtaa atcaaattct tgtgtttttc taaccacttt ttttcttctt
     3241 ctgtaaatgg aagtgacttc ttaatatatt caaatacatt tagattatac tccatattta
     3301 catacatatt tgtaagtgaa aatactacta aaaatgaata aataatccct ataataacaa
     3361 tctttttttt attcacttta aaactccaat cttctttttt actataataa attcaatatt
     3421 taataacaaa atcctacttt tttcattaaa tatttatatt tattataaaa ctaattgaat
     3481 agatgttgaa attatagtca ttactattcc tatcaatgct tcatatggaa ttaacttaaa
     3541 tctttcacct atatccatgt ttatactacc tgcactagta tgaaatagtg agccatgtgg
     3601 taattgctcg aatacactag acccagcatt tactattgat gcacctgaaa tcggtgatag
     3661 cccaccattt attatagcat catgaaaagt agatgatgct atagtagcac cagctgttga
     3721 tgatgctgtt gctaatgaca taagtatacc cgaaactggt gccaataaaa attgtggcat
     3781 atttaaaaat tgtaaagcac ctattgtact ctgttgtaat tcagacatct gtataattcc
     3841 tgcgatagtc cctgttccaa gtaataatat gcatacccct tgcatcttag ataatccaaa
     3901 agctaaatat tctcttgaat tgttcaagtt tcctgtgaca attagagtta cgattcctcc
     3961 tattggaagg gctatcatag ggtctataac tataggagat acatttccta aaaacaatag
     4021 aaatatagct ataattggac cacataatga tttaaataaa cttggtaaat cttctctttg
     4081 ctctaaaatt tcatatgatt gtactttgtt tcctttattt attaatatac ttgctaaaat
     4141 aactgtaata acaactccaa taattgctgg aattatattt gccatcataa cactagagag
     4201 attgacagaa aaattatctg ctactgctat agtatttgga tttggtgata ttatattacc
     4261 tgctttaccc cctcccaaca tagctaatag tattgacaat ttagaataat ttaattttct
     4321 acctatatat aatcctatag gtgctacagt tattatagat acatccaaat ttacacctac
     4381 tccagcaagt accatagttg aaatggcaat cgaaaataaa gccctctttt caccaaatat
     4441 ttttacaatc tgttctgata ttttatctac tgcccctgtt tttattaaac ttccagctaa
     4501 tacacctgat gccaaagctc taagaattga tggtgatata ttcatagctc catttgccat
     4561 aaaatctaca gtttgtgtta tatttgctcc tccaactaat cctccaataa atgctcctaa
     4621 cattaaacta tatacagctt gaaatttttt tataattaaa ataattgcta ttaataaacc
     4681 aaatatagct ccaaaagtcg ttatttgcat aatatcccct cctatcataa attaactatc
     4741 ttttgcttaa ttttatttaa atatatttta agtattctgt atccactttg tcaattatat
     4801 tttaatttat ttaattatat tgaacatagt tttttcaaaa cctaattcta tatgttataa
     4861 taatttcata ctacataatc attttacttg attattttaa gttaatattt tttaaattaa
     4921 aaagagagga tatttatatg aatgatttaa atttagggga aaaaatagct gaagttcgaa
     4981 aaaaacaaaa cttaagtatt cgagatttag caaaactagc tgatgttaca ccatcattat
     5041 tgagccaaat agaacgaggt cttgctaatc catctgtaaa ttcattaaaa tctatagcct
     5101 cttctctaaa cgttccttta tttacatttt ttgtatctga agtagataaa aaaaacttga
     5161 tagtaagaca tgataataga aaaaaagtta ttttacctgg aagcaaagaa gttatatatg
     5221 agattttaat tccagactct agtggtaatt tagaatttgc aattatggat ttagctccaa
     5281 acacttcttc ttgtgttgat aggattactc ataatggaga tgaaattgca tatgttttgg
     5341 agggagaagt taaacttttt atggatgatg atgaatttac tttgtccaaa ggagatagtg
     5401 taaaagttcc tttaggaaca aaacataaat ggcaaaatga ctcaaatagt gaaagtaaag
     5461 taatttttgc agtcatcttg taaaggagta aaaaccatga agacatataa atttatattt
     5521 tttgatgcag atgatacttt atttgatttt aagaaaagtg aatcacatgc ttttaaaaaa
     5581 cttctatctg agtttgattt agaatttaat tttgagaatt atatagagtc atatagaaat
     5641 ataagtgata agctttggct cgaccttgaa aaaaatatta taactttgaa tgaacttaaa
     5701 ttacttagat ttgaactttt tgcaaataaa atatctttgg atgttgattc tgaaactctt
     5761 agcaaaatgt acttaaattt tttaggtgaa tgtacatttt taattccagg tgcaatcgat
     5821 atattacaat atcttaaaaa aaagtatact attgttataa taacaaatgg aatttctgca
     5881 gttcaaaaga aaagacttga aaattcaaaa ataaaagaat atattgatgg aatggttgta
     5941 tctgaagagt tgaaaatatc aaaaccaaat cctgaaatat ttaaatacgc tctcaaaaag
     6001 tttaattgtc atgataaatc ttctgcctta atgattgggg atagcttaac ctctgatgtc
     6061 ttaggtggaa taaattcagg aatagatact tgttggttaa attccaataa cagtataaat
     6121 tatactaatc atataccaac ttatgaaata aatacactta ttgaattaaa gaaactacta
     6181 tagtttgtaa gtctgttcaa attaaataga atattacttt gcaataattt ttttagttta
     6241 tacataaaat gaccaaaaaa attattgcaa ttcatacaca aaacaaatct tagtcttgaa
     6301 aactagttaa aagcattttc taggacattt gctacatctt gattctaaat tttcttcatc
     6361 ccccattaaa ataagcattg caacactttt tatgggggat agttgatgat aatcattgat
     6421 ttctatttct atactattat atttattttt tacatagtta taaatatcct tttgtctctc
     6481 tacttcaaaa tctttatctc ctggatatat ttcatgcgat attttgagac tatcatactt
     6541 tccttttaaa tacattttta ttttctcatt aatataatct aaacatacta tacctatttt
     6601 atccaatgct atccctgcca tcatattgca attttccata tagtcattca tcttaaaatc
     6661 aattttatcc cctattgtat atagtacagc aaatgctttt ttacattctt taggtgtttt
     6721 attaatatca acttcactta tatatatctt gatatctaaa atatcattta tatttcttat
     6781 ttctctttca acgattttac taattgtatc tggagctttt ctatttccat accccaaaaa
     6841 ctttagcaca atattcttat ctataaaaat atcatctaaa tttatatcct ttaaaagata
     6901 tttattttta ttactattat aattcatcaa tatcaatcct atctaattct ttataactaa
     6961 ttcttcctgc ctttatagct gcttgtaaat tttctactgg agtggtattt aagcagttac
     7021 agccaaaatc acataaaaag ttatcatatc ctctcatctt ctttaacaat tttagtgtct
     7081 ctcttctaat cttatctggc ttagaacgtc caagaagttt tattgggtct aaattaccaa
     7141 tcaaaactat atctctagga atcattggag caatttcttc atagtctaaa atttggtcta
     7201 aacttactgc atctatatta caacttagca tattatctaa taattctctg gtgtctccac
     7261 atatatgcat acctttccaa caatcaagtt cattgtagat tttatttaaa ttttttacta
     7321 taaattcatc aaatctatct ttacttaggg ttactgatgt tggctctgct attgaaatat
     7381 attttgctcc tgctttattt gcagctacag catatcttct taccaattca gttgtaaatt
     7441 ccaataattc ttctacaaat tttttatcag ttattataca tcttaaaagt tgagtagctc
     7501 cagctaattg acctgcaagt gtaaatggac cttgtatcga ttcatatagt ggttttttaa
     7561 tactttttga tataactgat aagctctcta tattgagtgg catacgtcca ctcgtataag
     7621 ggtctggaac atctaatttt cttaatttat ctctgtcagt tatagtatgt gtcaatacac
     7681 ttggaaaatc ataatctggt cttaatgtat ctaaacccag agtttcacaa aatgtaatcc
     7741 catcacagaa tgagtatata aaatctgatt caaaatactt gtccatagtc tttgctaatt
     7801 ctaattgcaa atctacacta tcatatactt catatgcctt tttatttatt aagaacaatc
     7861 catttgtacc catatcaggc agaaaaaaac ctctatcttc actatttata tactgaagta
     7921 aagtcatatc tgaaaacatt taaacttcac ctcctataag tttatttatt aatttaactg
     7981 cttttggagc atttgaactg tatccatctg ctcctatttc ttctgcaaac tccatactta
     8041 caggtcctcc accaattatt acttttggtc ttttatctat ctcaatcata ttaagttcgt
     8101 ctataaccga tttcatattt tccattgtag ttgtcatcat tgaagataag cctattatat
     8161 ctacattgtt ttttatagct tcttctatta tatcttcact ttttctattt acacctaagt
     8221 caataacctt atatccagtg gcttctacca ttacttttac aatatttttt cctatctcat
     8281 gagtatctcc ttctactaca gacatcagaa ttactccctt tgattttttc tttacttttc
     8341 cagttccctt caaaagatta atacctttat ttaatgcatc tgtgcatact ataacttctg
     8401 aaagataata ttccttattc tcaaacttat ctaaagctcc tatcatacct ttgtttaaac
     8461 catattcata aatatcttcc acatcaatat ttttatctat agcaattttt actaaattct
     8521 ctatattatc tacacccata tttaatatac attctgctat atcatcaagt atgtccatat
     8581 aatactcatc ctttctaatt acttacaaaa ttgctttttc aatatccaat aatttctctt
     8641 atttaacaag gactaactct aggtatcaat caattttatt taatatcatc taaaactatt
     8701 gataatttaa atttgcagtc catggaaaat ctacaggaaa tgcctttgta gcaaattcat
     8761 atatattttt tagatgttta aattcattgt actgttcctc atttttttca aaaaacagtt
     8821 tattaagctt atccaaattt tctattacaa gttcttcttc tttgtattta ataatatatt
     8881 tattttcaac ttgtttaaat tccatgtatt ttagtaattc aaaatctgca tattgactaa
     8941 aataacttct taaactatca cacaacttag taaaatttat tattttcata gttccttgtt
     9001 gataatccaa agattttgtc ccattacatt tcaactggtc tttaagattt ttcacatgta
     9061 ctttataatt taaagattct aatccaaatt tatttgcaac atatttcaat atattttcaa
     9121 catttacaga gtttaaccct atttcagcaa cttctcctac agtagaatct tcttttttta
     9181 ttgttcttat tatcaaatat cctattatat tattattttc ctttataaat accttcttgt
     9241 aaccaattgg tccccaggca atagttgctg catgcaatag tttttgaaac tcatctctcg
     9301 ttcttataaa tctagtacta ttttgattat atagttcaat cattttatct aaatcattat
     9361 ctttttcaaa attagtttca tcaaattcaa ctatttcata tgctattttt acatcttcag
     9421 gttttattgt atatttataa aaactcttta ccaaactaca atttcttcta ctgtatagac
     9481 ttcttgttcc tgatataatt acaatatcta caccatcata aaacattttt tcttctactt
     9541 tatccaatat cttagatgaa tagcctctct tttcataatc tggatgagta catactccac
     9601 ctatagctgc aaccttcaat ctgtttcctt gaatagatac atcctgaatt agatagttta
     9661 catcagaaac cactttatca tcttctgata ttataatcat attttctata ttatttttac
     9721 ttagtaaaag aggaaattct tccatcatag ttggtttatg atttcttgat attctaaata
     9781 catagtttat taattctatt actttatcaa attcttctaa ttttgcactt cttggtctta
     9841 attccattca tattcctcca aatattattt aagatactta aaactctatt atctataata
     9901 aaacatttat tactacagtt ctaattatat cttttttctt tacaattttt aattgttttt
     9961 tttagcaaat ttttataaaa tataaaccta atttatagtt aaatttataa aataacccgt
    10021 tatgtataat atattaaaat attttctata tatttatatg actaagttct ataactaaat
    10081 tgaaataatc actttttcaa gaatgttata atttttttat tgtattcttt ttgctatagt
    10141 ctatgaataa atcaatagaa aatcttctaa gttgctttta aataatgact ttatggttca
    10201 attgtactaa aatagtatat gtaggttaca aataatctaa taaatattaa agtttggagg
    10261 taatagatat ggcagattgt aattcatgtc catcaaaggg aaattgtaat agtcaatcaa
    10321 attgttctat tgaaaataac cctaacaata aatttggaaa aataattggt gttatgagtg
    10381 ggaagggtgg agttggaaaa tcaactgtaa ctgctttact tgctaataag ctaaacaaaa
    10441 tgggatataa ggttggtata ttagactcag atataactgg accaagtatt cctagactta
    10501 tgggtgtaaa aaatgtaaaa gcttattctg atggctctta tatttaccct gtagaaaact
    10561 caaataacat aaaagtaatg tctataaacc ttatgataga tgatgaaaat gaacctgttg
    10621 tttggagagg acctttactt ggaggggttg taaagcaatt ttatactgat gtactttggg
    10681 aagaattaga ctatttatta atagatatgc ctcctggtac tggagatgtt gccttaacag
    10741 ttatgcaatc tatccctata agtggaatag ttatggtttc agtacctcaa gatttggtat
    10801 ctatgattgt atcaaaagct gttaatatgg ctaaaaaaat gaacataaat gtccttggag
    10861 ttattgaaaa tatgagttat atccaatgtc ctgattgttc taaaaaaatc aagttatttg
    10921 aaggagaatc tactgaaaag tttttagatg atttagactt agagctttta ggagaacttc
    10981 ctatgactaa agaaattata gatattactc ataatggagt tacagaaatt agtgatgatt
    11041 tagattcaat attgactaat gttgttgaaa aaattaaata aataaaaatt ttataatttt
    11101 atatttatca aaaaaagagg cttgtattta ttttataatc atacaaataa atataaacct
    11161 cttttatgtt tatctatgtt ttaaatacac aaaatattct tctacttcat ctccattttt
    11221 tacttttact aaatattcat tataatgagc attatatggc tgtgtcattt tgcattctat
    11281 tacattttct atgtcttcta attctaaaag ttctacatcc tttaaaaatt ttctttctat
    11341 gagttccatt aatctttcca taatatatcc tcacttcccc tataattaag ataaactata
    11401 tatcctctta atgcagagtt tatctgttta ttatattata tccaatatat tacagtttct
    11461 aacatcattc ataaattatt ttaacaaata gagattgatt ttttaataaa tatgccttga
    11521 taaaatgaaa catagaccaa ctcttagttt tatgtaaaga aaacttaaag aaaactataa
    11581 attatattca caaaaattac tcagaagata taacagtaag taatatatgt aatgaattac
    11641 aacttaataa aagttatttt ttctttgttt aagaaaaaaa gtggatatac ttttactaat
    11701 tttttaaata aagttagagt tgaaaaaagc aaaaagtata tattaaaaaa aaacttgtct
    11761 attttagacg ttgctgtact aattggattc aatagtcaaa attactatag tataattttt
    11821 aaaaagttta ataactttac accaattgaa tataaaaata tttataacta aaaaatatca
    11881 ttctaaaagg atgttatttt tttacatatt ttttacaatt atagttaatt ctttgttaaa
    11941 ttgattgtac ataaaatact aaaaatctaa gttcaagtat ttaaattgct atatatcata
    12001 aattttctaa aattaacaac aacttaaaaa tttaacattc tcttaacgta tacttaacaa
    12061 aacattaata tttttattga caaaatttgt tattctatat tatggaaaca ataaatttta
    12121 gttaataaag tttataattc agataaaaaa attattaatt tcttaaggga ggaaatatcg
    12181 tgaatatagt aattagcctt atcggtggac ttggactttt tctttacgga atgagtttaa
    12241 tgggagaagg tttacaaaaa tcagcaggag acaaattaaa aaaaattatt gaactcttaa
    12301 caagtaatgt tgttatgggt gtactggtgg gtacagtcgt tacaggtatt atacaaagtt
    12361 caagtgctac tactgttatg gttgtaggat ttgtaaatgc aggtataatg aatctaagtc
    12421 aagctattgg tgtaataatg ggggcaaata taggtactac agttactgct caattagttt
    12481 catttaatct tgaaggaatt gcaccaattg ctttaggtat aggtatttta ttctatttat
    12541 ttacatcaaa tcaaaaaaca aagcatttgt ctgagatact tataggtttc ggtatattat
    12601 ttacaggaat ggagtttatg aaagatgcag tagctccact tgctgaatac aaagcattca
    12661 ctgatgcact tttatatttt agtaaaaatc ctgtattagg tatattggca ggatttgcca
    12721 taactggtat tgttcaaagt tcaagtgcat ctatgggtat gttaatagca ctagcttctc
    12781 aaggaatact tcctctatca tctgctttac ctattcttta tggagataat ataggtactt
    12841 gtgttacttc acttttatca agtgttggtg caagtagaaa tgctcgacgt gcagctgtaa
    12901 tgcatttaag ttttaatgta attggtacaa taatatttat gcttgtttta aataaaccta
    12961 tatcagccat agttactcat tttgacccaa ctgatacagc tagacaaata gcaaatgcac
    13021 atactttatt taatcttaca aatgttataa tattattacc attttctaaa tacatagtta
    13081 aattagcaaa tagacttata cctattaaag aaactgaatc agaaatagta aataatacta
    13141 agtacttaga tgaaaggatg tttagcactc catctatagc acttggtaat actgtacaag
    13201 aagttgtaag aatgggtcat aaagctacaa actctttgga acattcaatt gcaggatttt
    13261 taaataagag caatgaagat attaataaag cttttgagtc agaaaaagtt gtcaataagt
    13321 tacagaaaga tatattgaac tatttgttaa aactttctaa agaacctctt agagatgatg
    13381 aacgctttag aacagatttg ctttttaata ctgtaaatga cattgaaaga gtctctgacc
    13441 atgcagaaaa tatagctgaa ttggccatga gtgttaagga aatgaacatt agtttttctg
    13501 atagtgcgat aagagaaata tacgaaatat acaataagac aattactaat tttaaggatg
    13561 ccttaatagt tttagatgtt aaagattttg agttagcaaa taaagtttta gaagttgaaa
    13621 atgaagtaaa ttatttagaa aaaactttta gaaattcaca tatgattaga ctaaataatg
    13681 gaagttgtac aattgatgct ggtgtacttt atcttgactt acttactaat ctagaaagaa
    13741 tttctgacca ctcaacaaat atagtaaaac aagtactaaa acttaaacaa aaaatatagt
    13801 gattattttt atatataatc ttaatcaatg agaagtaaga agctatagat aatgcttata
    13861 tcatttatgg cttcttattt tttatgtaat actcaaattt ttatagtatt ctcttattat
    13921 taaacaattt ctgcctagaa tattccatat atatatgact tctttcataa aacttgaact
    13981 gcccataact aaagtcacaa gtatatataa ctatttttta atcaattata accaatattt
    14041 gttttattta tcttcatttt aattcttcat tcaataatgt aataagatta ttttttattt
    14101 ggatactatt atatcatcta aatatgttat tatatatttg gatattttca tattaatagg
    14161 agggattcta caatgataaa ttatatggta gaaattatat atagcgaaaa aataagcgaa
    14221 gtagaaaaca tgttgaaaat tgaaaatata caatatgaat ttacttctcg tgatggcttt
    14281 atattttttg gtttttatga tatgacagac gcatatagat ttgagacttt atgttcagat
    14341 gaaaaaattc gatttaaaag aatataatag ataaaaaagt acatatttct aaactatttg
    14401 tttttcaaat ttaggttgtg ttttaatgta gtgttgatat tataaacaat tttaataata
    14461 aaaaagtagg gacattatat taatatgctc ctacttttta ctcatactta ttaatattat
    14521 ttatcaaaat taccctacaa actggaattt atcattcttt cataatttta aactatcata
    14581 tttaaaatat ataaaattct acatgatttt tgtataaaca taatatcaac cattatccaa
    14641 tttaaaaata ttttttagta atttccattt cattttctct taacatatta attaaacttt
    14701 tatatgtaaa tggtgtattt acatattatt taatatccaa caattatata aagaaatgtg
    14761 ctctttgcct tataaagaat tataaagcca attcgtttta ttatattatt tttctttata
    14821 ccttaaaaac tttaccttca aattcttatt tatctatata ttataaaaat gttcttaacc
    14881 tcttttacga gattttcttg acatattatc agttagataa aataattaaa taatataatc
    14941 agtaagtatg ttttttactc ttttaagtaa atttccacct gcaccccaat caatttttaa
    15001 aattccaatt gcactgcctg ttgaagtagc tttaataact gtttttcctg tggtattttc
    15061 ataaactact attaatcctg catcactatt atttcttgca taatacttct caaaagttgt
    15121 aattagtata aatttatcat ctcctaaatt ataagaatca ctaaaaacta aatctgcatc
    15181 aagattttct tttatcattt tttgtgcctc taagggtgta atttttacag taaatatttc
    15241 tgttgccatt ttttatctcc tcataagaat ttattttaga caaaacataa tctctagtat
    15301 tttctgatat atttatcaaa caatatccct attcctccta acagagctaa tatagaacca
    15361 aaatttctat attgagaaat agattggtct agataaatat tatattggtc agtatccatg
    15421 attccaccat tttgttgaat aatatgctct gcactaaatt cacctaaacc tatacaacag
    15481 aataatacta ctactccaat tacaaaagca aatatacata ttgttaattt aaaatcctta
    15541 ttttccatag ttatccctct cataagctaa atttatttga ttatttttac tagattttat
    15601 attact
//
LOCUS       DAEORM030000078        15500 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.081, whole genome shotgun sequence.
ACCESSION   DAEORM030000078 DAEORM030000000
VERSION     DAEORM030000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15500)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15500)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 15500)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15500
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.081"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            complement(138..425)
                     /locus_tag="KRH23_003357"
     CDS             complement(138..425)
                     /locus_tag="KRH23_003357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226629.1"
                     /translation="MRLNVTKQNTIEVENSRKEDVYFVIVDNVFFERQGDVFNSITNN
                     NLNNYDVKILPTDNVFLELKITSTKDLEPVFIVVEDRQYNHGSIMFKPVLV"
     gene            complement(445..720)
                     /locus_tag="KRH23_003358"
     CDS             complement(445..720)
                     /locus_tag="KRH23_003358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226630.1"
                     /translation="MSLFVGGWSKFRAVEEEDLKVFNEAVGMLEGVGYEPLIVSTQVV
                     AGTNFKFICNATSVTNPPQNYLAEIVVFKPLPCDEHNATITSINIIK"
     gene            complement(1354..1533)
                     /locus_tag="KRH23_003359"
     CDS             complement(1354..1533)
                     /locus_tag="KRH23_003359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6440 family protein"
                     /protein_id="HHS5226631.1"
                     /translation="MGKDRFEKVYSQGKINATEIWVDKETGVNYVFHYYGNAAGFTPL
                     LDREGKPVISPIVSK"
     gene            complement(1818..3284)
                     /locus_tag="KRH23_003360"
     CDS             complement(1818..3284)
                     /locus_tag="KRH23_003360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HHS5226632.1"
                     /translation="MKRKPQYLIIFEHIIQQIYTGKITIGDRLDSIKSMSEEYMVSKN
                     TIKTVIKMLSEKGFIETKAGSRPVLIQSTSKQSIESDLLYEKILQISEIYKIFSLIFP
                     SIAMYNIKRFTSKDFEELNEIIDCMEKNSSNYLVFKEQRLKYINKLISKTNNFLIHHF
                     CEIIQHDVIISQLAYNFDNLDNCCIDFFRNKYIEQVRKTYLYGLDGNLIEFKKLLTYM
                     YKVCRESILKMVENRAPQSIDTSSFNSVTLEKCYLYDLIVSDVICQIFEGNIKIGDCL
                     PSITSIINRYNVSLPTVRSAYNELNELGIAKTINGKGTYITLFSEYDDDYINTEEGAK
                     RLSLLLDAMEFVTITLEDVVLLLGNKMDLIAVDKIETHLRYLQNNCEECKVYPDFVLL
                     CKIVDYTQIYVLQETFLHLKQYMIFGIYLERFFHEEYNEILKTRFDVCFEILRYLKKG
                     DVERFAESFSNIFKESLQYLKKVISSLNVDMRVKLDIL"
     gene            4232..5143
                     /locus_tag="KRH23_003361"
     CDS             4232..5143
                     /locus_tag="KRH23_003361"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0052621 - diguanylate cyclase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HHS5226633.1"
                     /translation="MAVISFCILHLITVSTISLVKNTSPDIIFANMTYKLISILIASI
                     LDFILWYSMNKIKEHIYIITQNQIEFSLFLKFSWFTLGYILFDSIQITFAPPSSLTSY
                     FILGSNILLILQLIIFINHIYSIEKNIYLEKEHHRLKMIKQEQLLKVNLLKKKANIDE
                     LTSAYNRKFAFEKIQHYIDNNLLFSLIYIDLDKLKTINDTYGHLAGDNYIINFSSIVI
                     ENLGIDDIFARIGGDEFIVIMPKSNKNTTKEFIEKISKIMDNKISFSYGIVEVPSKSK
                     MTVEEIINIADIRMYTNKQNNHKRNNN"
     gene            5475..6374
                     /locus_tag="KRH23_003362"
     CDS             5475..6374
                     /locus_tag="KRH23_003362"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020397798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0052621 - diguanylate cyclase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HHS5226634.1"
                     /translation="MSIVLNMPAYLFDSNSITNIYRVFSILLSFIVTGLYFSYKNHKN
                     NKINFEAVLEDKKNLIFLLSLMFGMYLYLCLSLSIYYTVGNVLILKLYGIKSAIIVLV
                     GNYIAERYSFRITQIKGYDIKNQIEYVESVKTEYEINKLNDIVYTDLLTGFYNRPFVN
                     QKLSEWTSNHYKFTLCFTDLNSLKPVNDKFGHQFGDKYISTTAQIIKKLINVENSLLF
                     RYGGDEFLFLLQNTSCVEAEKIMININYELSKLSNTDEYPYALSISYGLVEWDGISDI
                     ETLISKADSLMYENKLKNKSTLN"
     gene            6577..6732
                     /locus_tag="KRH23_003363"
                     /pseudo
     CDS             6577..6732
                     /locus_tag="KRH23_003363"
                     /inference="COORDINATES: protein motif:HMM:NF012772.6"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
     gene            complement(6992..9559)
                     /locus_tag="KRH23_003364"
     CDS             complement(6992..9559)
                     /locus_tag="KRH23_003364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002602373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PEP/pyruvate-binding domain-containing protein"
                     /protein_id="HHS5226635.1"
                     /translation="MIYYVLPLEHKQATIEIVGGKGMSLSKLLTAGIPVPDGFHVTTA
                     SYQSFVETNHIQSRINKLLDGIDSNNTSQLEDVSKKIGELFHNGEMPQEVSDAIKTAY
                     AGLGNISVAVRSSATAEDLPDASFAGQQETYLNIQGEDKVIDAVKRCWASLWTARAIA
                     YRVKNNIKHEIVALAVVVQKLAFSDSSGIMFTLNPINGRRSEMIINAAWGLGEAVVSS
                     LVTPDTIVVDKDSERIISYEVANKEIMTVRTSEGTEETMVPERLRKKYALTRNQVMQL
                     IQLGKKIEKYYQMPMDVEWALEKDKLYIVQARPITVLPPEWVLPEQDVVYTKGSLAEH
                     LPNPVTPLFATLGLEIVNRASELLWIDMFGKSAKKLLPKNGAYTVINGYVYLSAKSKP
                     LLIAIKSLSPRSLRRTLMNSVARWETARKGYEDAIKQWEEKPLHTMNAYQIMEGIQTI
                     FYAACIYFTRIQLTLPAASISETLFTKLFQGAVRRAGITDTSVFLLGFDTIVLQSEKE
                     LWGISEWVKQNNSINLYLQNSSAIKIAEDFMSSVVPVGVSQEVWIEWKNRINKYFKEF
                     GRTAYEFDFAHSTPQETLTPTFESVKTFVEGKGESPFLRQTTFEKRRKHAEEEILQHI
                     GGLRKKLFFKLLHWAQETSPMRENAIYLMGMGHPLIRCMFQEISERFIRGGAISHLDD
                     IYWLTKSELEVLIEQLDKNKSLSDMNGIIPVRKAELKKYMGYVSPSKLPEKNKKTISQ
                     AQQKQKDGKIVLTGIGTSTGVVTAPACVLNSPADFESFQPGSVLVAVTTTPAWTPLFS
                     SASAIVTDIGGPLSHSSIVAREYGIPAVMATHIATRTIKSGQMITVDGLAGTVTFDE"
     gene            complement(9562..10167)
                     /locus_tag="KRH23_003365"
     CDS             complement(9562..10167)
                     /locus_tag="KRH23_003365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HHS5226636.1"
                     /translation="MPKGIVLTPEQQAERREKIVAVALSLMAENGFQKTSMREIAVLA
                     NMGKSSLYDFFKTKDEIVVYAVEKEIEKTIQQVHRIIDGEPSPQQCLRKIMLNHLRFP
                     EQYRTVLMWLNTESDYLEEEYRKRLKDARYAYQDIIKSVIDNGVTTGIFRKTDTALVT
                     RLLINSMLSISYTSRPSDSLEKMLDETMNIFLHGIMNDGGE"
     gene            complement(10541..12001)
                     /locus_tag="KRH23_003366"
     CDS             complement(10541..12001)
                     /locus_tag="KRH23_003366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HHS5226637.1"
                     /translation="MFNELKTKENVYKNLINGKWIESNSRKPIEIYSPIDNSLVGKVQ
                     SMTKHEVDEVIKNTKESIKVWAEMPVYKRANIFHKAADLLLENIDEIANILVLEIAKD
                     IKSARAEVERTADFLRYTADVGKNMEGEAISGDNFPGGTRNKMSYVSRVPLGTVLAIS
                     PFNYPVNLSMSKIAPALIGGNAVVLKPATQGAISALHVVEIMRKAGIPDGILNTITGR
                     GSEIGDYVVTHKGINFINFTGSTEVGQHISKISGMVPLLLELGGKDAAIVLEDADLDF
                     AAKNIVSGAYSYSGQRCTAVKRILVQESVADKLVGKIKPLVETLTIGNPMDEVVITPL
                     IDNKATDFVQGLVDDALHKGAKLITGNVRKNNLFYPTLLDNVNVDMKIAWEEPFGPVL
                     PIIRVKDINQAIEIANQSEYGLQSSVFTSDIDKAFYIADKLEVGTVQINNKTERGPDH
                     FPFLGVKASGMGTQGVKYSIEAMTRPKAVVVNVREL"
     gene            12340..12918
                     /locus_tag="KRH23_003367"
     CDS             12340..12918
                     /locus_tag="KRH23_003367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HHS5226638.1"
                     /translation="MAKSFTEIEKDNIRKRLISECEINWSKYGYKKTNIDELCSKSGI
                     AKGSFYTFFDSKEKLFFEVLNGIQNRLISSVDEILSNMPPKEGFAKALKMLYRLYDKN
                     PFLYSPTNTDYITLLNKIPKEMLSQLEYSNVQSFYSLIERHNLKLKIEKEKAFGVCNA
                     LLSSLLLKEDIGYDYIEVFDFMVDNLVEHILE"
     gene            12969..13202
                     /locus_tag="KRH23_003368"
     CDS             12969..13202
                     /locus_tag="KRH23_003368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226639.1"
                     /translation="MIELIQRLNDIIYKINDKLNIHTKLVDPSSELMPLYSILSIIVS
                     IFLIILGIKVRKKFLIIIAIISIIVNVLIILDR"
     gene            13211..14461
                     /locus_tag="KRH23_003369"
     CDS             13211..14461
                     /locus_tag="KRH23_003369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HHS5226640.1"
                     /translation="MVKSSNTFNKNFNLMILGQIISLFGASILKFALSLYILDITGKA
                     EIFATILAVSSIPIIVFSPIGGAIADIFNRRNLMVIFDFSSSLTVLILAVFLFNNNGS
                     ILLVGIIMTILSVISTMYQPTVQSSTPLLVDNEHLMNANGIVAGVASLTNIAGPVLGG
                     VLYGVIGINAIIVISCVSFFLSAIMEIFIQIPFIKQEQNSNIIKTIFTDIKDGIVHIC
                     KENRFILKILFLAIAINLFLSSMLIVGIPYIVKITMGASNFLYGLAEGAISFSSLVAA
                     VSIGIFSKHLKITNLHISFIICAVMFIPMAVSVYPFILNTGFPVPFLIFIVSSMLIFF
                     TTTLISIYVITVTQLKTPNELLGKVMSILFAGTAIAMPLGQVMYGKLFDLLSDRVYII
                     ILGVGFITLLIAFVSKITLRNENL"
     gene            14622..15191
                     /locus_tag="KRH23_003370"
     CDS             14622..15191
                     /locus_tag="KRH23_003370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HHS5226641.1"
                     /translation="MSYMPTLEQAWEILRKYNKEEFHIRHAQIVSGVMRYYAKEYDPE
                     RVEFWEIVGLLHDLDFEMYPDEHCVKQRELMTELDLDKSIIDSTISHGYGLTGSDVKP
                     EQFMEKVLFAVDELTGLIGAAAIMRPSKSVSDLELKSVKKKFKDKSFAAGCSRDVIRS
                     GAEMLGWELDKLIQTTIEAMRSLIPEMAI"
BASE COUNT         5378 a         2529 c         2027 g         5566 t
ORIGIN      
        1 agttcaacta tactggttta aataggttat ctttatttgc ttaaattagt tcaactatac
       61 tggtttaaat aggtttcctt tagtttaaat aattcaccta tacctacttg aatagttcac
      121 ttttatttgc ttaaattcta taccaatact ggcttaaaca ttatactacc atgattgtat
      181 tgtctatctt caactacaat aaaaacaggt tctaaatctt tagtagatgt tatttttaat
      241 tctaaaaaaa cattatcagt tggtaatatt tttacatcat aattatttaa attattatta
      301 gtgatactat taaatacatc accttgacgt tcaaaaaaaa cattatcaac tattacaaaa
      361 taaacatctt cttttctact attttcaacc tctatagtat tttgtttagt tacatttagt
      421 ctcatcttcc acctcctatt aatattactt aattatatta atacttgtaa ttgttgcatt
      481 atgttcatca caaggaagag gtttaaaaac aactatctct gctaaataat tctgtggagg
      541 atttgtaact gaagtagcat tgcaaataaa tttaaaattt gttcctgcta caacttgagt
      601 agaaacaata agtggttcat aaccaacccc ttctaacatt cctacagctt cattaaatac
      661 ttttaaatct tcttcttcga cagctctgaa ttttgaccat ccaccaacaa aaagactcat
      721 ataaaaacct cctttatata tatatttatt tatatatagt agtaccaatt ttctcaatat
      781 tcaatatttt ctgtgtaact ggtcaatgaa aatgcataac tggataaaaa tacttataaa
      841 ataacttaac tttacatata aatagcttac tttacatgta ataagattat tctacaatat
      901 gaaatacatc ttgttttgaa tatattctaa atacaataat ggatattttc aattattatc
      961 cttagaaaat atccattact taacttgttt tatttaaaat cacatagaga ctttattatt
     1021 ttttttattg catgaatagc tatttcaggt atcataaggt gatatacccc ctccttgaaa
     1081 ccacaaaaaa catgacaaac tttacgaatc ttggcttaaa aaactacagg tacattcctt
     1141 atttgtggat tggagtagcc ataacaagca aattttacaa tttttatgat gacaaaatca
     1201 ataaaatcgc ttagtatata acacgaaaca ctacttgttg ctattaagaa tagttagata
     1261 ggaagtatgc attataccaa taaaggaatc aataaagaaa gttaaaacat ccctacaaat
     1321 caaaaatctg ttacattttt ctatatttaa acgttattta cttacaattg gagaaataac
     1381 aggttttcct tctcggtcaa gtaaaggcgt aaatccggct gcatttccat aatagtggaa
     1441 tacatagttc acacctgttt ctttatccac ccaaatctcc gttgcattta tttttccttg
     1501 tgaatatact ttttcaaatc tatcttttcc cattttataa tcccccatat ttttgattgg
     1561 tctatacctt cttcacttaa gtcgaaaaaa tacataactt atttttttaa ttctaatatg
     1621 aacacgtaaa aatgtcaaac agcttattta atttcataac ttcatgttac tgttcgtaac
     1681 cttgtttgtt tacttacact acattacagc accattttac cctttacatg attgtattgc
     1741 acacagcaaa aatgcttact ttattggatt tttcaactaa aaaaaggttt ttttctccac
     1801 agaacattta ctatttttta taatatatct aattttactc tcatatcaac atttaatgaa
     1861 gatataacct ttttcaaata ttgtaaagac tccttaaaaa tattagaaaa agattctgca
     1921 aatctctcaa catctccttt ttttaaatac ctaagtatct caaaacatac atcaaaacgt
     1981 gttttcaaaa tttcattata ttcttcatga aaaaatctct ctaaatagat tccaaatatc
     2041 atatattgtt ttaaatgcaa aaatgtttcc tgtaatacat aaatttgtgt ataatctact
     2101 atcttacaaa gtaaaacaaa atctggataa accttacact cttcacaatt attttgtaag
     2161 taccttaaat gagtttctat tttatctaca gctatcaaat ccattttatt tcctagtaaa
     2221 agtactacat cctcaagagt aatcgtaaca aactccatag catccaaaag caaactcaac
     2281 cttttagctc cttcttctgt atttatataa tcatcatcat attcagaaaa aagtgttata
     2341 tatgttccct tgccattaat tgttttagca attcccaatt catttagctc attataggca
     2401 cttctaactg ttggaagaga tacattatat ctattaatta tcgaagtaat tgatggtaga
     2461 caatctccta ttttaatatt gccttcaaaa atttgacaaa ttacatctga aacaattaag
     2521 tcatataaat aacatttttc caatgttaca gaattaaaac tacttgtatc tatactttgt
     2581 ggagcacgat tttctaccat tttaagtatg gattctctac aaactttata catatatgtt
     2641 aatagttttt taaattcaat tagattcccg tccaatccat ataagtaagt ttttcttacc
     2701 tgctctatgt atttattacg aaaaaagtct atacaacaat tatccaagtt atcgaaatta
     2761 taggccaatt gtgaaataat gacatcatgc tgaataatct cacaaaaatg gtgaatcagg
     2821 aaattatttg ttttacttat tagtttattt atatatttta gcctttgttc tttaaagact
     2881 aaataattag aactattttt ttccatacaa tcgataatct cgtttaattc ttcaaagtct
     2941 ttagatgtaa atcttttaat attgtacata gcaatagaag gaaatattaa actaaaaatc
     3001 ttatatattt ctgatatttg taaaatcttc tcatataata agtcagattc tattgattgt
     3061 ttactcgtac tctggattaa aactggtcta gaaccagctt ttgtctctat aaagcccttt
     3121 tctgagagca tttttattac agtttttata gtattttttg ataccatata ttcttctgac
     3181 atgcttttta tagaatcaag cctatctcca atagtaattt taccagtata aatttgttga
     3241 attatatgct caaaaataat taaatattgt ggttttctct tcatattttt cctcttcgat
     3301 aaattagatt tattgttttt tgtaaggtat atttactttt atttaatagg gcaaaatagt
     3361 tgcttatttt ttcctcataa tctataatta atataaacca tttatatata tggtctaagt
     3421 tttataatac tgtaatgcag taaaatagca tgttgtagct atactacagc aaattaacat
     3481 accattgtag tatattaatt ggaataattt taagtacttc aaaattccag caaaacatat
     3541 atgtgttttt gatattatgt atattcgtta atagaatagc tatacttgtt ttacataata
     3601 aattatatga tacttgctat atgtaattac tatatttaat acacatagtt atcatatata
     3661 ctatatataa ttactatact tggacacata gttatcatac atgctatatg taattactat
     3721 acttatacac ataactatta tactttccat acataattac tatatttgga cacatagtta
     3781 tcatacatac tgtatattaa gatataatac tttttaaatt ttatataaca cagacacatg
     3841 caataaaaaa taaggtatcc ataataagct ctttgcatgt acctaaataa aaactgtaaa
     3901 atagaatata taaaatctaa tctattttaa gtaaatacaa tttcacttta aaagaggatg
     3961 tactatgaaa taccatatat ttttaatcat aactactata ttaataatcg aactatgtaa
     4021 catttacata tgcaaaatag catcttttgg aaacaaaaat ataactatac ataagaatta
     4081 caaatatatt tttttaataa aaccattaac cttcttgata ataatattca caaaattacc
     4141 attaccacta tattatatat tgttttacat agtaagtcat aaattgctct taagcagaaa
     4201 aagttctact aacaaccatt ttattcccaa tatggcagta ataagttttt gtattttaca
     4261 ccttattact gtaagtacaa tatcacttgt taaaaataca agtccagata taatatttgc
     4321 aaatatgacc tataagttaa ttagtatttt aatagcttct attttagatt ttatcttatg
     4381 gtactctatg aataaaataa aagagcatat ttatataata actcaaaatc aaatagagtt
     4441 cagtctattt ttaaaattta gctggttcac tttaggatat atattatttg atagtataca
     4501 aattacattt gctccaccaa gttctctaac ttcctacttt atattgggaa gtaacatatt
     4561 attaatctta caactaatta tattcatcaa tcatatatat tccattgaaa aaaatattta
     4621 tttagaaaaa gaacatcata gactaaaaat gataaaacaa gaacaattac taaaagtaaa
     4681 tttattaaag aaaaaagcta acattgatga attaacatca gcatataatc gaaaatttgc
     4741 ttttgaaaaa atacagcatt acattgataa caatttatta ttttcattga tatatatcga
     4801 tttggataaa ttaaagacga taaatgatac atatggacat ttagctgggg ataactatat
     4861 tattaacttc tcaagtatag ttattgaaaa cttaggaata gatgacatat ttgctagaat
     4921 aggaggagat gagtttatag ttattatgcc taaatctaat aaaaacacca caaaagaatt
     4981 tatagagaaa ataagtaaaa ttatggataa taagatatct tttagctatg gtattgtaga
     5041 agttcctagc aaaagcaaaa tgactgtaga agaaattatt aatattgctg atattagaat
     5101 gtacactaat aaacaaaata atcataaaag gaacaataac taaaatgaat atttacatga
     5161 gcttacttgt agtctcacta tgttttttat cttattatct ctatcattat aattttttta
     5221 aatatctaga cataatgatt aataactcta aaaataaata caaagtatac attgtatact
     5281 ctctttttaa ttatttaatt tttattattt gtacttattt aaggttacat ctagttataa
     5341 attggacaat ttttatgtta gttttattta tgcaaattaa agtaacttac aaactttcca
     5401 caataaaaaa ccttttttat tcgttaaact gctccatcat tggtttagca ataaatatat
     5461 tttttaggtc tttaatgtca atagtgttaa atatgccagc atatttattt gatagtaatt
     5521 ctattacaaa tatttacaga gtattttcta tattgcttag ttttatagtt acaggattat
     5581 atttcagtta taaaaatcat aaaaataata agattaactt tgaggcagtt ttagaggaca
     5641 aaaaaaactt aattttctta ttgagcctta tgtttggaat gtacttgtat ctatgtttga
     5701 gtttgtcaat atactatact gttggaaatg tattgatttt aaaattatat ggaatcaagt
     5761 ctgccataat agttttggta ggtaactata ttgcagaaag atatagcttt agaattactc
     5821 aaataaaagg ttatgatatt aaaaatcaaa tagaatatgt agaaagtgta aagacagagt
     5881 atgaaattaa taaattgaat gatattgtat atacagattt actgacaggc ttctacaata
     5941 gaccttttgt aaatcaaaaa ctatcagagt ggacatcaaa tcactacaaa tttaccttat
     6001 gttttactga tttaaatagc ttaaaacctg taaatgataa atttggacac caatttggtg
     6061 ataaatacat atccactact gctcaaataa taaaaaaact tataaatgta gaaaattcct
     6121 tactgtttag atatggtgga gatgaatttt tattcctttt acagaataca agttgtgtag
     6181 aagcagagaa aataatgatt aatataaatt atgaattatc aaaattaagt aatactgacg
     6241 agtatcctta tgctctttcc ataagctatg gattagttga gtgggatgga atatccgata
     6301 ttgaaacttt aatatcaaag gcagattctt tgatgtatga aaataagctt aaaaataaat
     6361 ctactttaaa ctagctagtt aagatattct acaaaatata tattataaga gagtactaag
     6421 aatgtcaaaa tatatagatt ttgcaaatat tgaatacatt ttactaatga atgcactgga
     6481 tgtaagtgtt agtaaacacc tattagatga acactttact gttgtttggg ctaatgaccg
     6541 ttattatgaa atgttcggct atacctagct aaaaagttaa aaatgaccac tgtagccgag
     6601 ggaatagaga ccagttttca aaaagatttc ttgcaagaaa taaactgtga tatgttacaa
     6661 ggatacgtgt tctctagacc tttaccaata aaagactttg aaaaacttat gtttcaaaac
     6721 tcctccaatt aacaatataa aattgcttat tataagtgat attattgtat caacaaataa
     6781 aggaattgtc tcaaaattga ttttttctaa tcaaattttt attttgagac attctcattt
     6841 ttttgcataa gaaaataccc accaagctac ggtttttctt accgctgttc ggtgggtatt
     6901 agtagtatta tgaaatctga aaactttaag tattactact tccgctaacg caatcacaaa
     6961 ggtcgaaagc ttcaaagcga aaataggctt tttactcatc aaacgtcacc gtacctgcca
     7021 acccgtccac cgttatcatt tgtccgctct taatagttcg tgtggcaatg tgtgtagcca
     7081 taacggctgg gatgccatat tcacgtgcga caatgcttga atggctaaga ggaccaccaa
     7141 tgtccgttac aatcgcactt gcagatgaaa ataatggtgt ccatgctgga gttgtggtaa
     7201 ctgcaaccaa aacacttcca ggttgaaagc tttcaaaatc tgctggacta ttcagtacac
     7261 aagctggagc cgtcacaaca ccagtactgg taccaatgcc cgtcaacaca attttcccat
     7321 ctttctgctt ctgttgtgct tgtgatatag tttttttgtt tttctctggc aacttggatg
     7381 gtgacacata acccatgtat tttttaagtt cagcttttcg aacaggtatt atcccattca
     7441 tatcagatag agacttgttt ttatccaact gctctataag tacctccaat tccgattttg
     7501 tgagccaata aatatcatct aaatgtgaaa tagctcctcc tcgtatgaat cgttctgaga
     7561 tttcctgaaa catacaacga atcagaggat gtcccattcc catcaaataa atagcatttt
     7621 cacgcatagg agaggtttcc tgtgcccaat ggagcaactt aaaaaatagt tttttacgca
     7681 atccacctat gtgttgtaaa atctcttctt ctgcatgttt tctacgcttt tcaaacgtgg
     7741 tctggcgtaa aaaaggactt tccccttttc cttccacaaa tgtttttacg gattcaaaag
     7801 ttggtgtaag tgtttcctgc ggtgtggaat gcgcaaaatc aaactcataa gcggtacgac
     7861 caaactcttt aaaatactta ttgattcgat ttttccattc tatccatact tcctgtgaaa
     7921 ctccaacagg cacaactgaa gacatgaaat cttctgctat ctttattgca gaactgtttt
     7981 gcagataaag gttgatgctg ttattttgct ttacccattc tgaaataccc cacaactcct
     8041 tttccgattg cagaacaatc gtatcaaacc caagcaggaa aacggaagta tccgttatac
     8101 cagcacgtcg aactgctcct tgaaataatt ttgtaaataa tgtttcactg atagaagcag
     8161 caggcaatgt aagctgaatc cttgtgaaat aaatacatgc ggcataaaat attgtctgaa
     8221 taccctccat aatttgatag gcgttcatag tatgcagggg cttttcttcc cattgtttaa
     8281 tagcatcctc atatcctttt cgtgccgttt cccagcgtgc aacgctgttc ataagtgtcc
     8341 tacgtaaaga gcgtggggaa agggatttga tagcaatcaa aagtggcttt gatttagcag
     8401 aaagataaac atatccatta ataaccgtat atgccccgtt ttttggtaat aattttttcg
     8461 cacttttacc aaacatatct atccataaaa gctctgatgc acggtttacg atttcaagac
     8521 caagcgtagc gaacaaaggt gtaacaggat ttggcaagtg ttctgccaaa cttccctttg
     8581 tgtatacaac atcctgttct ggcaataccc attctggtgg cagaacagta attggacgag
     8641 cctgaacaat gtacaattta tctttttcca gtgcccactc tacatccata ggcatttgat
     8701 aatacttctc aattttcttt ccaagctgta tcagttgcat tacctgatta cgagtaagag
     8761 catatttttt tctcaacctt tcaggaacca tggtttcttc tgttccttct gaagtacgaa
     8821 ccgtcataat ctctttattt gccacttcat acgatataat tcgttcggaa tccttatcca
     8881 ctacgattgt atcaggtgta actaagctag aaaccaccgc ttcaccaagc ccccatgcag
     8941 cgttaataat catttcgcta cgtctaccat tgattgggtt taacgtaaac ataataccag
     9001 atgaatcgga aaatgcaagc ttttgtacta caacagcaag tgcgacaatc tcgtgcttta
     9061 tattattctt cacacgataa gcaatagcac gagctgtcca taaggaagcc cagcatctct
     9121 ttacagcgtc aataacttta tcttcacctt gtatgttaag ataagtttcc tgctgacctg
     9181 caaaagaagc gtcaggtaaa tcttcagcag tcgcagacga acggacagcc accgatatgt
     9241 tccctaatcc ggcataagcc gttttaattg catccgacac ttcctgtggc atttctccat
     9301 tatggaaaag ctcccctatt ttcttagata catcttcaag ttggctggta ttattggaat
     9361 caataccatc tagcagttta ttaattcgag actgaatatg gttcgtctca acaaaactct
     9421 ggtatgaagc agttgtaaca tgaaaaccgt ctggcacagg gatgcctgct gtcaatagtt
     9481 ttgataaaga catccctttt ccaccaacaa tttcaatggt tgcttgttta tgttccagtg
     9541 gcaagacata ataaatcata atcattcacc tccatcattc ataattccgt gcagaaatat
     9601 attcattgtt tcatccaaca ttttttccaa actatccgat ggtcgtgacg tgtagctgat
     9661 tgataacata gagttaatta acaaacgtgt cacaagagcg gtatccgttt tgcgaaagat
     9721 gcctgtggtc acaccattat caattaccga ttttataata tcttgatatg cataacgagc
     9781 atctttaagt ctctttcgat actcttcttc taaataatca gattctgtat ttaaccacat
     9841 cagtacagtt ctatactgct ctggaaatct aagatgatta agcatgattt ttctaaggca
     9901 ctgttgtggt gaaggttcac catcaataat cctatgaact tgttggatag ttttttctat
     9961 ttctttctca actgcatata caacaatctc gtctttcgtt ttgaaaaaat cgtatagact
    10021 tgactttccc atgttggcta aaactgcaat ttctctcatt gatgtttttt ggaatccatt
    10081 ttcagccatg agactcaaag caacagcaac tattttttct cggcgttctg cttgttgttc
    10141 gggtgtaagc acaattcctt ttggcatagg gcgatacctc cttttagcga ccgctggtcg
    10201 tttctttttt atttatcata cagcgaccaa cggtcacttg tcaaggttaa tttttttcat
    10261 tgtatatggt actcgagata aaaatgttca ttttagaaat tgctctattt aagtagaaat
    10321 aggcttcatc attagaaaac aagactataa atttgagata tttatcatgt tcaaatttca
    10381 tcaatatcaa agtttaaaat attaataaaa aaagaattac taagaaataa catataaaga
    10441 ttcaaaaaag gagttgaact taaaattcaa ttacaaaaaa tcaaatttaa gacaactcct
    10501 ttattcttta tctctactat tctttatctc tatttattta ttacaactcc ctaacattta
    10561 ccactactgc cttaggtcta gtcatagcct caattgaata cttaacacct tgagttccca
    10621 taccagatgc ctttacacct aaaaatggga agtggtctgg acctctttca gtcttattat
    10681 ttatttgaac agtaccaact tcaagtttat cagctatata aaatgcctta tcaatatcac
    10741 ttgtaaatac tgatgattga agcccatact ctgattgatt agcaatttca attgcttgat
    10801 ttatatcttt aactcttata attggaagta ctggaccaaa tggttcttcc caagcaattt
    10861 tcatatcaac atttacatta tctaacaatg ttggatagaa taaattattt tttctaacat
    10921 tgcctgttat taactttgct cctttatgta atgcatcatc aactaaccct tgaacaaaat
    10981 cagttgcttt attatctata agaggagtga taactacttc atccattgga tttccaattg
    11041 tcaacgtctc taccaatggc tttatttttc cgaccaattt atccgccaca ctctcttgta
    11101 ctaaaattct ctttactgcc gtacatcttt gtcctgaata tgaatacgct ccagatacta
    11161 tattcttagc tgcaaaatct aagtctgcat cttctaatac tatagccgca tcttttccac
    11221 caagctccaa taataatggt accattccag atattttaga tatatgctga ccaacttcag
    11281 tactaccagt aaaattaata aaattaattc ctttatgcgt tacaacataa tctcctatct
    11341 cactacccct acctgtaata gtattaagta ttccatctgg tatcccagct tttctcataa
    11401 tttctaccac atgaagtgcg ctaatagccc cttgtgtagc aggttttaat acgactgcat
    11461 ttccaccaat aagtgctgga gcaatctttg acattgataa atttacagga taattaaaag
    11521 gagatatagc taaaacagta cctaatggaa cccttgaaac ataagacatc ttatttcttg
    11581 ttccaccagg gaaattatct ccactaatgg cttcaccctc catatttttt cccacatcag
    11641 ctgtgtatct taaaaaatct gctgttctct caacttctgc ccttgcagat tttatgtctt
    11701 tggctatttc aagtaccagt atattagcta tctcatctat attttctaac aataaatcag
    11761 cagccttatg aaatatattg gctctcttat atacaggcat ttcagcccat acttttatac
    11821 tctcttttgt gttttttata acctcatcta cctcatgttt tgtcatagat tgtactttcc
    11881 caacaagaga attatctatt ggtgagtaaa tttctattgg ctttctcgaa ttagattcta
    11941 tccattttcc atttattaaa tttttatata cattttcttt tgttttaagt tcattaaaca
    12001 tatttttatt cctctctctg atataacttt gtgtatttaa attatagcca tttattcgtt
    12061 atgtaaacat ttcttttttt cataaacgtt tacctataaa aaaaatttta agttaacgtt
    12121 tttctacatt cttctatttt aataacatac tcgctccaaa tctatatagg tcacacttta
    12181 atactaatat accaatatac taatatatca atataccaat ataaatatta taaacataaa
    12241 tcacttgaca aatttataag tagacaatat tatatatcta tgacttaaaa tatttttgaa
    12301 gtcatagata tcatatatag acagaaagga ttgataaaaa tggctaaaag ttttacagaa
    12361 atagaaaaag acaatataag aaaaagacta atttcagaat gtgaaatcaa ctggtctaaa
    12421 tatggataca aaaaaactaa tattgatgaa ctttgttcaa aatcaggaat tgcaaagggt
    12481 tcattctaca cattctttga ttcaaaagaa aagttatttt ttgaagtatt aaatggaatc
    12541 caaaacagac ttatatcatc agtagatgaa attttaagta acatgcctcc aaaagaaggc
    12601 tttgcaaaag ccttaaagat gttgtatcga ttatatgata aaaacccatt cttatattca
    12661 ccaactaata ctgattacat cactttattg aataagatac ctaaagagat gctttcacaa
    12721 cttgaataca gcaatgtaca aagtttttat agcttaattg aaagacataa tctcaagtta
    12781 aaaatagaga aagaaaaagc ctttggtgtt tgcaatgccc tactgtcaag cctattgcta
    12841 aaagaagata ttggatatga ctacattgaa gtatttgatt ttatggtaga caatcttgta
    12901 gaacacatac ttgagtaata atttaaaata aattttctaa acatttcttt ataactagga
    12961 ggagtaatat gattgaatta atacaaagac taaatgatat tatttacaaa ataaatgata
    13021 aactaaatat ccacacaaaa cttgtagacc ctagcagtga gctcatgcca ctttactcta
    13081 tattatctat aatcgtttct atatttctaa taatattagg tattaaagta agaaaaaaat
    13141 tccttataat aattgctatt atatcaatta ttgtaaatgt tttaataatc ttagataggt
    13201 aggtgcatat atggtaaaat cctcgaacac ttttaataaa aacttcaact tgatgatatt
    13261 aggtcaaata atctcattat ttggtgcatc aatacttaaa tttgctttat ctttatacat
    13321 acttgatata actggtaaag cagaaatatt tgctactata ctagcagtat cttcaatccc
    13381 aattatagta ttctccccta ttggtggagc tattgcggat atattcaaca gaagaaactt
    13441 aatggttatt tttgattttt caagtagtct tacagtacta atcttagcag tattcttatt
    13501 caacaataat ggttcaatat tacttgtagg aattattatg accatattat cagtcataag
    13561 cacaatgtat caaccaactg ttcagtcaag tacacccctt ttagttgata atgagcattt
    13621 aatgaatgca aatggtattg tagctggagt tgcatctctt acaaatattg caggacctgt
    13681 attaggaggt gtcttgtatg gtgtgattgg aattaatgca attatagtta taagttgtgt
    13741 aagtttcttt ctatctgcaa ttatggagat atttatacag attcctttta tcaaacaaga
    13801 gcaaaacagc aacattataa aaactatatt tactgatata aaggatggta ttgttcatat
    13861 atgtaaagaa aatagattta tactaaaaat acttttttta gctatagcaa taaacttatt
    13921 tttaagctct atgttaatag ttggtatccc ctatatagta aaaatcacta tgggagctag
    13981 taacttctta tatggtctag cagaaggagc aatttctttt agttcactgg tagctgctgt
    14041 tagtattggt attttctcaa aacatctaaa aatcactaat ttgcacattt cctttattat
    14101 atgtgcagtt atgttcatac caatggcggt ttcagtatat ccatttatat taaacacagg
    14161 atttccagtt ccatttttaa tctttatagt atcatctatg ctaatatttt ttacaacgac
    14221 tcttatctca atatatgtta taacagtcac acaattaaaa actccaaatg aactcttagg
    14281 aaaagtaatg tcaattcttt ttgcaggaac agcaattgca atgccccttg gtcaggttat
    14341 gtatggtaaa ctttttgatt tattatcaga tagagtgtac atcattatac taggagttgg
    14401 atttattaca ctgcttatag catttgtatc aaagataaca ttgaggaacg aaaatcttta
    14461 gatacaaaga atttagatat aaagatttaa ttttcactaa tttctgaatt taaatgcaaa
    14521 attgtgtatc agtatgttga cgttttagaa attgattgat ataatcaatg gaaaataaac
    14581 tttataaaaa ttcaaaatat tcagctagag gagtgataaa aatgagttac atgccaactt
    14641 tagaacaagc atgggaaata ttaagaaaat acaataagga agaatttcat ataagacatg
    14701 ctcaaattgt atctggagtt atgagatact atgcaaagga gtacgaccct gaaagagtag
    14761 aattttggga aatagttgga cttttacatg atttagattt tgaaatgtat cctgatgaac
    14821 attgtgttaa acaaagagaa ttaatgacag agcttgattt agataaatca ataatcgatt
    14881 ctacaataag tcatggatat ggattaactg gttcagatgt taaaccagag caatttatgg
    14941 agaaagtatt atttgctgtg gatgaactta ctggtttaat tggtgctgct gcaataatgc
    15001 gtccttcaaa gagcgtttct gatttagaat taaaatctgt taagaagaaa tttaaagata
    15061 aatcatttgc tgctggctgt tctcgagacg ttataagaag tggtgcagaa atgcttggat
    15121 gggaacttga taagcttatc caaacaacta tagaagctat gagaagcttg attccagaga
    15181 tggcaatata gctcctccat acatatacca tagaagttac atctttaaag agcatttctc
    15241 tttttgatgc aacttctttt tatattttgt agaataaaaa gtttaatatt ttaaactcac
    15301 tatataatct ataataaata ctataaataa tataatgtat aatagtcata aactttctaa
    15361 ccttaaaagt ttctaataat caataaacaa ttctaatata caaatgtcat tatatgattt
    15421 aattatatat cttcaattta tatattaaaa taaatatata tatattaaat tcttatacac
    15481 caaattttta cattaaactt
//
LOCUS       DAEORM030000079        15164 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.082, whole genome shotgun sequence.
ACCESSION   DAEORM030000079 DAEORM030000000
VERSION     DAEORM030000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15164)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15164)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 15164)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15164
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.082"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            complement(252..788)
                     /locus_tag="KRH23_003371"
     CDS             complement(252..788)
                     /locus_tag="KRH23_003371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0071453 - cellular response to oxygen
                     levels [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IbrB-like domain-containing protein"
                     /protein_id="HHS5226642.1"
                     /translation="MEYKSPVYGIIAVPIEKIESNDYNPNAVAPPEMQLLYKSIKEDG
                     YTMPIVCYYNEEKDKYIIVDGFHRYRVMLENEDIYDRENGLLPVSVIDKSLDERMAST
                     IRHNRARGSHNVDLMSKIITELCEIGKSDEWISKHLGMEVDEILRLKQITGLAYLFKD
                     KEFGNAWIPFGSDIEEEN"
     gene            complement(806..2119)
                     /locus_tag="KRH23_003372"
     CDS             complement(806..2119)
                     /locus_tag="KRH23_003372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoadenosine phosphosulfate reductase"
                     /protein_id="HHS5226643.1"
                     /translation="MDKRYLESDVFEAFQERLSYLFNEFDYIYVSFSGGKDSGLLLNL
                     VLDYKRKNNISSKIGVFHQDFEAQYSLTTEYVEKVFEDNIEDIEPYWVCLPMATRTAV
                     GNYEMYWYPWDDEKEELWVREMPVKEYIINQKNNPFTYYKYKMRQESLAKQFGRWIRD
                     IHEGAKVVCLLGTRAAESLQRYCSIVNKQHGYKGKCWITKEFKNVWTASPIYDWEIED
                     IWLAHYKFDYDYNKIYDLFYKAGVAPRKMRVASPFNDSAKESLNLYRILDPDVWVKLV
                     ARVQGVNFTSIYGKTKAMGYRSVKLPYGHTWKSFTYFLLDTLPENIRNSYIKKFSTSI
                     EFWQNTGGGLSEIVIHELLRKGYKIELNGVSNHTKDKKSRVIFLDDIPDDTDDIKFTK
                     DIPSWKRMCYCILKNDHMCRFMGFGPTKEQRIRTEYIKKKYEKIH"
     gene            2474..2914
                     /locus_tag="KRH23_003373"
     CDS             2474..2914
                     /locus_tag="KRH23_003373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3788 domain-containing protein"
                     /protein_id="HHS5226644.1"
                     /translation="MYERMLDKSNKPCLSQIIEYIGKDGYARLCKLETYLKTQYNLSR
                     ELRFPFGNNYGWGYKYSHKSFHLFYAFFEKGTFTVLIQIGDKQVPAVEKTLVALTPKA
                     KELWVTRYPCGNNGGWIKYRILEDADLLDIIQYIRAKKSPPKQN"
     gene            complement(3099..3287)
                     /locus_tag="KRH23_003374"
     CDS             complement(3099..3287)
                     /locus_tag="KRH23_003374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HHS5226645.1"
                     /translation="MNKNNNLVIICMFIGMILGMAIGCAIGISKGNVGITMCYGLIFG
                     MIIGICIGTIIKNSNKKE"
     gene            4292..4687
                     /locus_tag="KRH23_003375"
     CDS             4292..4687
                     /locus_tag="KRH23_003375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6110 family protein"
                     /protein_id="HHS5226646.1"
                     /translation="MNILKMKKTGIFLGGVLFGTVGVKILSSDCVKKTCTRATAGALK
                     VKDSVLETTTKIQENVEDILAEAKEINEQENLSTSKVNVVQDTLKCEQEVLKTETIKT
                     VEDTNSNSIKCEEIKDNVIEEKNSTCTTE"
     gene            4730..6829
                     /locus_tag="KRH23_003376"
     CDS             4730..6829
                     /locus_tag="KRH23_003376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042625 - ATPase-coupled ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HHS5226647.1"
                     /translation="MNFYIKHEIRGRIRFDLQLGKLNNKQSDTLLYYLTSINGITKAK
                     VYDRTGDAVIYYTGEREYIIREITKFSFNNSKIENLVPEHTSRELNNYYRDKLANKLL
                     VKSISKIFFPKSLRFFLIGLHSIKYFKKGLSSLLNKKIEVSVLDATAIGISIFRKDIN
                     TAGSVMFLLGIGELLEEWTRKKSIDDLAQSMSLNIEKVWLRKGDTEILIPISEIKEGD
                     LVSVTMGNMIPLDGVIVSGETMVNQASLTGESLAVNKKEGSYIYAGTVIEQGNIVMCV
                     KEKAGTTRFQKIVTMIEESEKLKSSVESKFEHLADTLVPYSFLGSILTYAITRNPIKS
                     LSILMVDFSCALKLSIPISVLSAMRECNNNNITVKGGKFLEGVACADTIVFDKTGTLT
                     KAQPTVSDIITFQNYNKEDMLRLAACLEEHFPHSIANAVVYEAEKQGLSHKEMHTEVE
                     YIIAHGISTKVDDKKVVIGSKHFVFEDEKCTIPDGEEDKYNNLSDEYSHLFMAISGKL
                     SAVICINDPLRKEAKYVISNLRECGIKKIVMMTGDSEKTAKSIASKVGVDEYYSEVLP
                     EDKANFVKSEKLKGRKVIMIGDGINDSPAISESDVGIAMSEGAEIAREISDITISADN
                     LNNLIVLKQISNKLMKRVDLSSKFIIGFNLGLILLGVGGFVRPSTSAFLHNASTVGIS
                     LNSMTNLLENTNTYNYH"
     gene            complement(7054..12264)
                     /locus_tag="KRH23_003377"
     CDS             complement(7054..12264)
                     /locus_tag="KRH23_003377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase"
                     /protein_id="HHS5226648.1"
                     /translation="MANKLYSEIVNLLEEGRDELRKYDLKEKSILLFLGASGVGKSTC
                     INYLKGCVMEEKTDEETGQIYITAKDSAVEIGNGVYSKTLCPEVVDIANRDFSLCDCP
                     GFFDNRGAEYMIAGAMLVRETISTSSKVKGMVVILDYQSLLDSRHTLLIETGKNLKDM
                     LGDYAKYKENFFFLINKIPKTLIGNVTEEKIRNILEKAKEDLDSQEKDYDGCKELVYL
                     LNVALSDGVSIKLCNPLDKQPEKLLNEMKNLPETFEKTDLGLMLTASCKIEIQKAVDV
                     TYKDLEKLLVPYIESVKKGMEDSISILSSINSLKDKKIQLDKMYTDLCSRTNNMKELM
                     EFVQELSYGDGVQKVNILEETRLLLELNSYCSETHIVGLSELLKSLLKNTLEDTLKDI
                     KYWIAEEEYREEEAKRLEDAEYRIEKIQSCTYIKSYEKENVLSIYIPIPKVNLSDLTK
                     IISGYQLNILSSIYMYGDCELKIDCNMEKEVFSGKNIVLLTEKLHIPEGTYSINVSGK
                     DAEKLVGESSIYDGMNGRNGNNAGTSGDILLSFKEIEKRGELKLYVDGGRGGNGQDGK
                     RGDTGITGEAGANAKIGSKKESKEFANVKGTKYYVVKAEKGKQGGTGGTGGNGGNAGL
                     GSKSGQVYLLGKAPLLKGAISKKDGNHGLAGKGGSGGAGGAGGFGGIRGIYEETIRYI
                     GTSTPIDDSDRNYYYFDRYVFNHASNENQVADDGEKLNALYEKHKDWTISKREDSGSA
                     GAEGKEGLSGDTLKEKELLKQEYSLSMDTFFYEFFERFGFSGSKGYRNLRLLCAVGIL
                     EADILELSHIYEIFHAVEKIEMQLNREILQKYYSFEKKNKAVLSLDDMNIKKEFYKEA
                     KEIYEYLINKLMQSDRIESFIGEKQNFSEWSMILFALEQKTAFYVQMIEESEIGGNRV
                     TDIRSLTDYLDKTLRELEQGKKDELKEGYFNTYKESILTQIESGNQQIEVLKNELENK
                     MLSVNAKMNLLIQEIIKIKEDEKEDIEKLKEKQAKLEEQMKTQLILSGIQSALSLLTA
                     FSGVGQACLGAFDSAKSLKENLSAKEEEYKWTNRMVDFSDFKLDSDGMRFVLGEQLSE
                     DRKNALDKMTYNLAGVDEERRTKFDQIKEIIVKSIDDDNYADKADDIQRAKEGLSESE
                     YKEIYTKIQKKEIGMLEANYNNKQQKDKLVALEKSKQAIERQQKTSKIKNALSIGSSA
                     CSLINTAISGVNNCLNVKSSFESKIEVVKEAIKDKENNIKKLDELNTQMVEFKDKTLK
                     ESVIPFVEKFDSTVKNQDIFENEISKLKMKEVLTELSTKFGSLKMENSEEISIIFKKV
                     QDMMETQIIITDKIDKKKDNLAMGELIYQMSDSGNQMNEYQKKLIHQIELNQVRYLCQ
                     VEAAAFQLWTFPFGSNIVNILNRCHVGITEDENEVINQAKEQNRQIREFLDQDAYQWQ
                     KTDNHILKVALTGSLDGKSRVGFENTYSLYDCNEEEVKKLLTGDEISFEVPLNKNFDA
                     IKYVTMYANIPNLRRNILEDSLKVKVHIHLYDSGYFSLYDDKKDVYYQYVFPQNYINI
                     THGLDVKYNDSDSINSIWSSVEDKGIEKFKNAGLNSGRSPYSMAKISLKAHFNRKLSY
                     DSLTNEQKKKLESYFDKPSKYAWSDSIDILKSLGYIDFKGILSKSWYEIKKDIDSDGE
                     IMKHFSILQVDLLERIIYEQTSILKENIPNLTIELVGCGIYVESEFNYLKQNDLKCYE
                     ERLVENTIIG"
     gene            complement(12279..14774)
                     /locus_tag="KRH23_003378"
     CDS             complement(12279..14774)
                     /locus_tag="KRH23_003378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HHS5226649.1"
                     /translation="MPENNNQLLEEITLLLNEGKVAINKAENQNLILILGGTGCGKST
                     AINYLAGCVMMEVEDEDTGISYIDCLDPVAEIGSGAVSQTLYPNIVNMRKPIEGMDAK
                     LCDTAGFSDNRGVAHDISAAVSLGEVFKNSASICAVIVLIPEADILDSRLTKVLDLFQ
                     QLNMCLHKENFKGSITFFISKSFLGRTEKQIYNVIKRKYEQLCENLDSNIEEKAWLFE
                     ELLKDNGKNIHLCKPLASDEREGLLKQVLELDEVKDKTSAFQYPISADARLVLDTLIK
                     EIQNNIVSSLEDYVKAYTEDFINIIGSITMIQEIAKYDEVVKVFKNWLESTTSLTIER
                     FINVLAKQSGLFLQDSCMKLQNKIKGNLDIIDALSKYTEHGTGEILLPSVHMEFIIEK
                     ASKKIMEQNFIIIRKNLEKVLVSYEVQKQVFTLPNREKLMEVANKKDYVYSVSDFNSI
                     LTNVTVTQNEELEDSITRLSAYGEEGNEIIREFIGKYILNPFIVKTININDKKGIEIR
                     ALIPNLVISSVLEYFKNRKVDDNVSTFMFFAKDTIYMDDNLGMDFASEKNIILASNNL
                     DVGSNVKINVSGKSGELVDNSMYGKNGEDGRDAGNIYLYIKEEIRNYRLTLIANGGNG
                     SKGIDGENGETGASGSNGADAGYTSYFHGQMFKGYFEKGTSGKKGEKGGAGGNAGRGG
                     NAGKKGNIYFISDSEEQKNRIINHCDITVKDGEAGPNGRPGLGGYGGSGGYHGYNTLS
                     FSPSGIDKTVYYTGYFTSWDYKLDSIIKYHIEFSGGSWNEGKTGPAREYAEYGDRGDN
                     GGFNAPNTKLSTAVSKVEENLIKEKYQGYCSEI"
BASE COUNT         4976 a         2705 c         1678 g         5805 t
ORIGIN      
        1 atgtgattat tttttattaa aaacgatata aatatacaat ttaatactat tttttaaata
       61 agcttatatt aaaatacatt tagtcatata attttattta ttttaatagt ataattataa
      121 aaataaaaaa agaataggat aattttccta ctcttttttc tgtacttaca tataatatta
      181 aaactcttta ttttttaata tatattttaa attttctttt ttaataaatc tttttctttt
      241 aataaatcta tttaattttc ttcttctata tcagagccaa agggaatcca tgcattacca
      301 aactctttat ctttaaataa ataagctaat ccagttattt gcttcaatct aagaatttca
      361 tcaacttcca tacccaggtg ctttgatatc cattcatcag attttccaat ttcacaaagt
      421 tcagttataa ttttactcat taaatccaca ttatgagaac ctcttgcacg attgtgtcga
      481 atagtacttg ccattctttc atcaagagat ttatcaatta ctgaaacagg aagaagtccg
      541 ttttctctat catatatatc ctcattttca agcattactc tatatctatg aaaaccatct
      601 acaataatat acttatcctt ttcctcatta taataacaga caattggcat tgtataccca
      661 tcttctttta tacttttata caacaactgc atttctggtg gggctactgc atttgggtta
      721 tagtcgttag attctatctt ttcgattggc actgcgataa ttccatatac aggactttta
      781 tattccatag catcttaact cctatctaat gaattttttc atatttcttc ttaatatatt
      841 ccgttctaat tctctgttct tttgtaggac caaatcccat aaatctacac atatggtcat
      901 tttttaaaat acaataacac attcttttcc aacttggtat atctttggta aatttaatat
      961 catccgtatc atcaggtata tcatccaaaa atatgactct actcttttta tcttttgtat
     1021 gatttgaaac tccatttaat tctattttat aaccttttct caataattca tgtataacta
     1081 tttctgacaa accaccacct gtattctgcc agaactcaat agatgttgaa aattttttaa
     1141 tatagctatt ccttatattt tcaggtaagg tatcaagcaa aaaatatgtg aaacttttcc
     1201 atgtgtgtcc atatggcaat ttaacactac gatatcccat agcttttgtt ttgccataaa
     1261 tagaagtaaa attaactcct tgtactctag caaccaattt cacccataca tctgggtcca
     1321 atattctgta taaatttaaa ctctcttttg ctgaatcatt aaaaggtgat gccactctca
     1381 tttttcttgg agctactcca gctttataga ataagtcata aattttatta tagtcatagt
     1441 caaatttata gtgtgctaac catatatctt ctatttccca atcatatata ggagatgccg
     1501 tccagacatt tttaaattcc ttagttatcc agcactttcc tttatatcca tgctgtttat
     1561 tcacaataga acaataacgt tgtagagatt ctgctgctcg tgttcctaat aagcaaacaa
     1621 cttttgcacc ttcatgtata tctctaatcc atctaccaaa ttgttttgcc aaactttctt
     1681 gtctcatttt atatttataa taagtaaaag gattattttt ttgatttatt atgtattctt
     1741 tgactggcat ttctcttacc cataactctt ctttctcatc atcccatgga taccaataca
     1801 tttcataatt tcctacagca gttcttgtag ccattggtaa acacacccaa tatggttcaa
     1861 tatcttcaat attatcttca aatacttttt caacatattc agtagtcaaa ctatattgag
     1921 cctcaaaatc ttgatgaaat actcctattt tggaacttat attattcttt ctcttataat
     1981 ccaaaactaa atttagcagt aaaccactat cttttcctcc gctaaaagat acatagatat
     2041 aatcaaattc attaaaaaga taagaaagtc tttcttgaaa agcttcaaat acatcggatt
     2101 ctaaatatct cttatccatt tgaattatcc cctttcaatt agaagtttat aaaaccttac
     2161 aatgcaatat tattatgctt ttttagcagt aatcagcata aattatacat tatttaaata
     2221 cacaaatcca actaaataca tataattata atgtaattat acttttgtat tataaactat
     2281 attttatcat tattttacat ttttttccaa tatatataat tatcatattt ttctattagc
     2341 taaaactaat taccttatat ttttacgtat tggtataata atacataaaa acttgaataa
     2401 tgcataaaaa cttgacatac tgttgtcata attactttac tataattaaa agtaaaaatg
     2461 gaggtaaatt ctaatgtatg aacgtatgct tgataaaagc aataaaccct gtttgtccca
     2521 aataatagaa tatataggta aagatggata tgcacgattg tgtaagttgg aaacttactt
     2581 gaaaactcaa tataatttat caagagaact tcgatttcct tttggaaaca attatggttg
     2641 gggttacaaa tatagccata aatcttttca tttattttat gctttttttg aaaaaggtac
     2701 atttactgtt ctgattcaga taggtgacaa gcaagttcca gcagtagaaa aaacgttggt
     2761 agctttgaca ccaaaagcta aagagctctg ggtcactcgt tatccttgtg gcaataatgg
     2821 aggttggatt aagtatcgta ttttagaaga tgcagactta cttgatatta ttcaatatat
     2881 aagagcaaaa aaatctccac ctaaacaaaa ttaactttta ttttttgtga tttaaatata
     2941 gtgtatataa attccattct ttccatataa aaaaaataat ataaaaaata tctattagta
     3001 taacttattt agtatgtctt attctacttt ttacagataa ttaaaaagtt ttatcataaa
     3061 taaatcataa ctagacatcc tagtaaatca aaattaattt attctttttt attagaattt
     3121 ttgataatag tccctataca tatgccaatt atcattccaa aaattagacc ataacacatt
     3181 gtgataccca catttccttt agaaatacct atagcacaac ctatagccat tccaagtatc
     3241 atgcctataa acatacatat aataactaaa ttgttgtttt tattcatagt ttttctccat
     3301 tcaatatatt ttaaattgcc tagctcgcct tcttagctta aaacaaagaa atataaatta
     3361 actttctttc attctaatat ctgcctgtat aaatgtcaaa caacacattt cttgtcataa
     3421 cctcctcttt ttgaagtaaa tacaatctcc cagacgcaat aatatcaatt tcctaaaacc
     3481 atttaagtaa cttttatatt tacataatat ttacaatcat aaactatatt gttattcatt
     3541 tatacatcat aaacactccc tcctaatcat tattatactt aaaataatgt tcatttataa
     3601 taatatatct aacgcacttt aattgaaaaa actaaaactt tgcctttcat tcccatatat
     3661 aaataagtat actttttgat gctctattac aaatcaacta aattaattga tataaattat
     3721 cattttctgt tgaaaatacc attcgcacat gctatactta attgcataaa tggtaataaa
     3781 tgtcatatga ttttacaaat ctattaataa caattattac ttttactgta ttttaaagtt
     3841 tttggactaa atatcaaaaa ctttctaaaa tacaaagtac aaaaaattta tataagttat
     3901 aaatttatat gaactagata agctcaaaca atatgttatg tataaactgt gtagtattcg
     3961 gttataaatt tatataaatt atataagcta gatatataaa ttgcatatat aagctatata
     4021 agaattattt caactatata aactacatat gtaaattaca tacataagct agatatataa
     4081 actagatata taaactgcat atataagcta tataagaatt atttcaacta tataaactac
     4141 atatgtaaaa ttcgtgtaaa tttactaata taaatcaaat aaaattacta aactctctaa
     4201 actaattttg taaaacatac tctattttta acatttgtta ccttatacat aagtacaaac
     4261 aaaatctaac taaatgaaag gataatgtaa aatgaatatt ttaaaaatga aaaaaacagg
     4321 gatattttta ggaggagtac tttttggtac tgtaggtgtt aagatacttt caagtgattg
     4381 tgttaaaaaa acttgcactc gtgcaacagc aggagcattg aaagttaaag attctgttct
     4441 tgaaacaact acgaaaattc aagaaaatgt agaagatatt ttagctgaag caaaagaaat
     4501 caacgagcaa gaaaacttat ctacatctaa ggtaaacgtt gtacaagata ctcttaaatg
     4561 cgaacaagaa gttcttaaaa ctgaaactat aaaaactgta gaagatacta attctaatag
     4621 cattaaatgt gaagaaatca aagataacgt aattgaagaa aaaaatagta cttgtacaac
     4681 agaataaatt taatgattat tatgattaat aatatcagga ggaagtaaat tgaattttta
     4741 tataaaacac gaaataagag gtcgtatacg ctttgactta caacttggca aattaaacaa
     4801 caagcagtcc gatactctct tatattattt aacttctata aatggtatta ccaaagcaaa
     4861 agtttacgat agaactggtg atgcagtcat ttattacact ggtgaaagag aatacataat
     4921 aagagaaatc actaaattca gttttaacaa tagcaaaata gaaaacctag ttcctgaaca
     4981 taccagcagg gaattaaaca attattatag agacaaatta gcaaataaac tgctagtcaa
     5041 aagtatctcc aaaatatttt ttccaaagtc cttaagattt tttttaattg gacttcattc
     5101 tataaaatat tttaaaaaag gtctctcttc cctgctaaat aaaaaaatag aagtttctgt
     5161 tttagatgcc actgctatag gtatttctat ttttagaaaa gatatcaata cggctggttc
     5221 agttatgttt cttcttggta tcggtgaact attagaagaa tggactagaa aaaaatctat
     5281 agacgacttg gctcaaagta tgtcactaaa cattgaaaaa gtatggttaa gaaaaggtga
     5341 cactgaaatc ttaattccaa tttcagagat aaaggaagga gatttagtaa gtgtaactat
     5401 gggaaatatg attccattgg atggagttat agtatcagga gaaacaatgg tcaatcaggc
     5461 atcacttaca ggtgaatccc ttgcagttaa caaaaaagaa ggctcttaca tatatgctgg
     5521 aactgtaata gagcaaggca atattgttat gtgcgtcaag gaaaaagctg gtactactag
     5581 attccagaaa atagtaacta tgattgagga atctgaaaaa ctaaaatctt ctgtagagag
     5641 taaatttgaa catctagcag atacattagt tccatacagc tttttaggaa gtatattaac
     5701 ctatgcaatt actagaaacc ctataaaatc actctctata ttaatggtag atttctcttg
     5761 tgcattaaaa ctctctatcc ctatttcagt actatcagcc atgagagaat gtaacaataa
     5821 caacattact gtaaaaggtg gaaaatttct tgaaggtgtt gcatgtgcag atactattgt
     5881 atttgataag acaggcacat taacaaaagc tcaaccaact gtttcagata taattacatt
     5941 ccaaaattat aataaggagg atatgttaag acttgcagct tgcttagaag aacacttccc
     6001 acactccata gcaaatgcag tagtttatga agctgaaaaa caagggctta gtcacaaaga
     6061 aatgcataca gaagtagaat atattattgc tcatggcatt tcaacaaaag ttgatgataa
     6121 aaaggttgta ataggtagca aacattttgt atttgaagat gagaagtgta ctatcccaga
     6181 cggtgaggag gataagtaca ataatctatc agatgagtat tcacacctat ttatggcaat
     6241 atcaggtaaa ttatcagcag ttatttgcat aaatgaccct ttacgaaaag aagcaaaata
     6301 tgtaatttca aatttaagag aatgcggaat aaaaaagatt gtgatgatga ctggagatag
     6361 cgaaaaaaca gctaaatcta tagcaagtaa agttggtgtt gatgaatatt attcagaagt
     6421 cttaccagaa gacaaagcca attttgttaa aagtgaaaaa ctcaaaggtc gcaaagtaat
     6481 tatgattggt gatggaatca atgattctcc tgctatttca gaatcagatg tcggaattgc
     6541 aatgagtgaa ggtgctgaaa tagcaagaga gatttcagat attaccatat cagcagataa
     6601 tttgaataat ttaatcgttt taaagcagat tagtaataag cttatgaaaa gagttgattt
     6661 aagttctaag tttattatcg gctttaattt aggtttgatt ttacttggtg taggtggatt
     6721 tgttagacca agtacatctg cctttttaca caacgcatct actgtcggaa taagtttaaa
     6781 cagtatgaca aatttattgg aaaacaccaa tacttataac taccattaat ctccattaca
     6841 taaaacatat gatataaaaa atttataatt catcttttta aaaaaatatg tcttaaaatt
     6901 agcttttttc taatcaaaat tatataaagc atactttaca aattttaaac tcaacttatt
     6961 tctatttttt acaaaaaagg agatgattca aattttcatt ttgaaacatc cccttttgta
     7021 aatttcttta aaatttatat attaattata ttttcaacca ataattgtat tttcaaccaa
     7081 tctttcttca tagcatttta aatcattttg ctttagataa ttaaattcag actctacata
     7141 aataccacag cctaccaatt caattgtcaa attaggtata ttttccttta gtatactagt
     7201 ctgctcataa ataattcttt ccaataaatc aacttgtaat atagaaaaat gcttcataat
     7261 ctccccatca ctatctatat ctttcttgat ttcataccaa ctctttgaca aaattccctt
     7321 aaaatcaata taccctagac tcttcaatat atctatacta tcgctccatg catacttact
     7381 aggtttatca aagtatgact ctagtttctt cttctgctca tttgtaagtg aatcataaga
     7441 aagcttccta ttaaaatgtg ccttcaaaga aatcttagcc atagaatatg gacttctacc
     7501 agagtttaat cctgcatttt tgaacttttc aattccttta tcttctactg aagaccatat
     7561 tgagtttatt gaatctgaat cattgtattt aacatcaaga ccatgtgtaa tatttatata
     7621 gttttgtgga aatacatatt gataatagac atctttttta tcatcatata gagagaagta
     7681 tccactatca tataaatgaa tatgtacctt tacttttaaa ctatcctcta aaatatttcg
     7741 tctaaggttc ggtatatttg catacatggt tacatatttt atggcatcaa agtttttatt
     7801 taatggaact tcaaaactaa tttcatctcc tgtcaaaagc tttttcactt cttcttcatt
     7861 acaatcatat agagaatatg tattttcaaa tcccacacgt gatttcccat ctaaactgcc
     7921 tgttaatgct accttcaaaa tatggttatc tgttttttgc cattggtaag catcttggtc
     7981 aagaaactct ctaatctgtc tattttgctc tttcgcctga tttataacct cgttttcatc
     8041 ttctgtaatc cctacatggc atctatttaa gatatttact atattgcttc caaatgggaa
     8101 tgtccatagt tgaaaagctg ctgcctcaac ctgacacaaa tatctaacct gatttaattc
     8161 aatttgatgg ataagttttt tctgatattc attcatctga ttaccactat ctgacatttg
     8221 ataaatcaat tctcccattg caagattatc ttttttctta tcaatcttat cagtaatgat
     8281 aatttgagtt tccatcatat cctgtacttt tttaaatatt atagaaatct cctctgaatt
     8341 ttccattttt aagcttccaa acttcgtgct taattcagtt aaaacttcct tcatctttaa
     8401 tttacttatc tcattttcaa aaatatcttg atttttaact gtactatcga atttttctac
     8461 aaatggtata acagattctt tcaaagtttt atctttaaat tccaccattt gagtattcaa
     8521 ttcatctaat ttcttaatat tattttcttt atctttaatt gcctctttaa ctacctctat
     8581 tttactctca aaactagatt ttacattaag acaattatta acaccactaa tcgcagtatt
     8641 tataagagaa caagcagaac ttccaatact caatgcattt ttaattttag atgtcttttg
     8701 ctgtctttca atagcttgtt tacttttctc tagtgcaact aacttatctt tttgctgttt
     8761 attattgtaa tttgcctcca acatacctat ttcttttttc tggatttttg tgtaaatttc
     8821 cttatactcg ctttcactta acccctcttt tgctctttga atatcgtcag ctttgtctgc
     8881 atagttatca tcatctatag acttaactat aatctcctta atttggtcaa atttagttct
     8941 tctttcttca tcaacacctg ccaaattata agtcatttta tctaaagcat tttttctatc
     9001 ttcacttagc tgttctccaa gtacaaatct cataccatca gaatccaatt taaaatctga
     9061 aaaatcaacc atcctgttag tccatttgta ttcctcttct ttagctgaaa gattttcctt
     9121 caaagatttt gcactgtcaa atgcccctag acaagcttga ccaacaccac taaatgcagt
     9181 cagtaaactc aatgcgcttt gtattccaga aagaattaac tgtgttttca tttgttcctc
     9241 aagttttgcc tgtttctctt ttagtttctc tatatcttct ttttcatctt cttttatctt
     9301 tatgatttct tgaatcaaca ggttcatttt tgcattaaca gaaagcattt tattctcaag
     9361 ttcatttttt aaaacctcga tttgttgatt tccagattca atttgtgtta ggatactttc
     9421 cttatatgta ttgaaatatc cttcttttaa ctcatctttc tttccttgtt ccaattctct
     9481 taaggtctta tccagataat ctgtcaaaga acgaatatct gtaacacgat ttcctccaat
     9541 ttcactttct tcaatcatct gcacataaaa tgctgtcttt tgttcaagtg caaataaaat
     9601 catactccat tcgctaaaat tctgcttttc tcctataaaa gattctattc tatcagactg
     9661 catcaattta tttataaggt attcatagat ttcctttgcc tctttataaa attctttctt
     9721 tatattcatg tcatccagag aaagtactgc tttatttttc ttctcaaaac tataatactt
     9781 ctgaagtatt tctctattta attgcatctc tattttctca actgcatgaa aaatttcata
     9841 aatatgtgaa agttctaaaa tatcagcttc taaaattcct actgcacaca ataatctaag
     9901 gtttctatac cccttacttc cagaaaagcc aaatctctca aagaactcat agaagaatgt
     9961 atccattgat aaagaatact cctgctttaa caattctttt tcttttaatg tatctccaga
    10021 gagaccttct tttccctctg ctccggctga acctgaatct tcacgtttgc taattgtcca
    10081 gtccttatgt ttttcataaa gagcatttaa tttctctcca tcatctgcta cttggttttc
    10141 atttgaagca tgattaaaca catatctatc aaaataatag taatttctat cactatcatc
    10201 tattggagtg gaagtaccta tatatcttat tgtttcttca tatatacctc taattccccc
    10261 aaaacctcct gcaccaccag ctcctccaga gcctcctttt cctgctagac catgattccc
    10321 atctttttta cttatagcac cttttaataa aggtgctttt ccaaggagat aaacctgtcc
    10381 agacttgctt ccaagacctg catttccacc attacctcct gtacctccag ttccaccttg
    10441 ttttcctttt tctgctttta ccacatagta ttttgtacct ttaacattag caaattcttt
    10501 tgactctttt ttagaaccta ttttagcatt tgccccagct tctccagtta tccctgtatc
    10561 tcctcttttt ccatcttgtc catttccacc acgtccacca tctacgtaaa gtttaagttc
    10621 tcctcttttt tctatttctt taaaagataa taaaatatca cctgaagtac ctgcattatt
    10681 tccatttctt ccattcattc cgtcgtaaat agaactttct ccaaccaatt tttctgcatc
    10741 cttaccagat acgttgattg aataagtccc ttctggtata tgtaattttt ctgtaagtag
    10801 tacaatattc ttacctgaga agacttcttt ctccatatta cagtcaattt tcaactcaca
    10861 atctccatac atatatatag atgacaaaat attaagttga taaccagata ttattttagt
    10921 caaatccgat aaattcactt taggtatagg aatatatata gaaagtacat tttctttctc
    10981 atatgatttt atatatgtac aactttgaat cttctctatc ctatactctg catcttcaag
    11041 ccttttggct tcttcttccc tatattcttc ttctgctatc caatatttga tatcttttaa
    11101 tgtatcttct aaagtatttt ttagcaatga ttttaacaac tcacttagac caacaatatg
    11161 agtctcacta cagtaactat ttaactctaa aagaaggcgt gtttcttcta atatattcac
    11221 tttctgtacg ccatcaccat atgaaagttc ttgtacaaac tccataagct ctttcatatt
    11281 attagtccta ctacataaat ctgtatacat cttatctaat tgaatctttt tatcttttag
    11341 actatttata gaagatagaa tggaaataga atcttccata ccttttttaa cactttctat
    11401 ataaggaact aaaagttttt ctaggtcttt ataggttaca tcaacagctt tttgtatttc
    11461 tattttacaa gaagcagtaa gcatcaatcc caaatctgtt ttttcaaatg tttcaggtag
    11521 atttttcatt tcattcaaca acttttctgg ctgtttatct agtggattac ataatttaat
    11581 agatacacca tctgataatg ctacatttaa taagtacact aattccttac aaccgtcgta
    11641 atctttctct tgactatcta ggtcttcttt tgctttttcc aatatatttc ttattttttc
    11701 ttctgttaca ttaccaatta gtgttttagg tattttattg ataagaaaga agaaattttc
    11761 tttatacttt gcataatcac caagcatatc tttcaaattt ttgcctgttt ctatcaataa
    11821 tgtatgtcta gagtccagta gggattgata gtctaaaata actaccatcc cttttacctt
    11881 tgaagatgtg gaaatagttt cccttacaag catagcacca gcaatcatat actctgctcc
    11941 acggttgtca aaaaaacctg ggcaatcaca taatgaaaaa tctctatttg caatatctac
    12001 aacttctgga cataaagtct tagaatatac accatttcca atttcgacag ctgaatcttt
    12061 tgcagttata tatatttgtc cagtctcttc atccgttttt tcttccatca cacagccttt
    12121 taaataattt atacaagtac tctttccaac gcctgaagca cctaggaata acaaaattga
    12181 cttttctttt aagtcatatt ttctaagctc gtctcttcct tcttccaaaa ggtttacgat
    12241 ttcactataa agtttatttg ccatacatcc atccctttct atatttcgga acaatagcct
    12301 tgatattttt ctttaataag attctcttct acctttgaaa cagctgttga taacttagta
    12361 tttggagcat taaatcctcc attgtctcct ctatctccat attcagcgta ttctcttgct
    12421 ggtcctgttt taccttcatt ccagcttcca ccactaaatt ctatatgata tttaattata
    12481 ctatctaact tataatccca acttgtaaaa tatcctgtat agtatacagt cttatctata
    12541 ccacttggag aaaatgaaag tgtattatat ccgtgatagc caccacttcc tccatatcca
    12601 cctaaacctg gtctaccatt tggacctgct tctccatctt tcactgttat atcacaatga
    12661 ttaattattc tatttttttg ttcctctgaa tctgaaatga agtaaatatt acctttctta
    12721 ccagcatttc cacctcttcc agcatttcca ccagctccac ctttttcacc ttttttgcca
    12781 cttgtacctt tttcaaaata ccctttaaac atctgtccgt ggaaataact tgtatatcct
    12841 gcatcagctc cattacttcc agaagctcct gtttcaccat tttccccatc tattccttta
    12901 gaaccatttc ctccatttgc aatcagtgtt agacgataat ttctaatttc ttctttaata
    12961 tataagtaaa tattacctgc atctctacca tcttcaccat ttttcccata catagaatta
    13021 tctacaagtt ctccgctctt tccacttaca ttaattttta cattactacc tacatcaaga
    13081 ttgttagaag caagaataat atttttctct gatgcaaagt ccattccaag gttatcatcc
    13141 atataaatag tatctttagc aaagaacata aatgtagaaa cattgtcatc tacttttcta
    13201 tttttgaaat attccaatac actgctaatt actaagtttg gaattaatgc tcttatttca
    13261 atacctttct tatcattaat attaattgtt tttactataa atggatttaa aatgtattta
    13321 ccaataaatt ctctaattat ctcattacct tcttctccat atgcacttaa tcttgttata
    13381 ctgtcttcta actcttcatt ttgtgtaact gtaacatttg tcaaaattga attaaaatca
    13441 cttacactat atacataatc ctttttattt gcaacttcca ttaatttttc tctatttggt
    13501 aatgtaaata cctgtttttg cacttcataa gaaactaaaa ctttttctaa attctttctt
    13561 attataatga agttttgttc cattatcttc ttacttgcct tttctataat aaattccata
    13621 tgtacagaag gtaataaaat ttccccagtt ccatgttctg tatatttact taaagcatca
    13681 attatatcta agtttccttt tatcttattt tgtaatttca tgcaactatc ttgtaagaat
    13741 aatccacttt gtttggctaa tacgttgata aatctctcta tagtaagact tgttgtactt
    13801 tccaaccagt ttttaaatac ttttacaacc tcatcatatt ttgctatttc ttgaatcatt
    13861 gttatacttc caataatatt gataaaatct tctgtatacg ccttaacata atcttctagg
    13921 ctagatacga tattgttttg aatttctttt atcaacgtat ctaaaactaa tcttgcatct
    13981 gcactaattg gatattggaa tgctgatgtc ttatctttaa cttcatctaa ttctagtact
    14041 tgctttaata agccttccct ctcatctgat gcaagtggct tacaaagatg aatatttttt
    14101 ccattatctt ttagcaattc ttcaaataac caagcttttt cctctatatt actgtctaaa
    14161 ttttcgcata attgttcata ttttcttttt ataacattat atatttgttt ttctgttctt
    14221 cctaagaaac tttttgaaat gaaaaaagtt atactaccct taaaattttc tttatgaaga
    14281 cacatattta actgttggaa caggtctagt acttttgtaa gtctagaatc taatatatct
    14341 gcttctggta tcaatacaat tactgcacat atagatgcag aatttttaaa tacttcacct
    14401 aatgaaactg ctgcgctaat atcatgggct actcccctat tgtcgctaaa acctgcagta
    14461 tcacataatt ttgcatccat tccttctatt ggttttctca tatttacaat gttcgggtat
    14521 aaagtttgag aaacagctcc tgaaccaatc tctgccacag ggtctaagca atcaatatat
    14581 gatataccag tatcttcatc ttcgacttcc atcattacac atcctgcaag atagttaatt
    14641 gcagtacttt tgccacatcc tgtcccacca agaattagaa ttaaattttg attttcagcc
    14701 ttatttattg ctacttttcc ttcatttaat aagagtgtta tttcttctaa aagttgattg
    14761 ttattttctg gcatttattt tcccccttgg ttatatattt tatttaaata aagtttaatc
    14821 ccttaagtag attacaaagt ttttagacta tatttaaatt tgttttttat tttttatttt
    14881 taataaattt gcattttcac taaatttgta ttttcactca ataattattc ttctttgttt
    14941 attaaaataa ctgtgttgta taatataatc tttaccaaca cagttattct atttaatgcg
    15001 cttattttat tgtattttat gtaatacagt tgttttttat attatatgtc cattattttc
    15061 ctatggttat tacatataga tttttaatta tatttgtacc attaatttaa acattcctat
    15121 actactgctt aagttttaca cctataccag cttgaatatt ttat
//
LOCUS       DAEORM030000080        14924 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.083, whole genome shotgun sequence.
ACCESSION   DAEORM030000080 DAEORM030000000
VERSION     DAEORM030000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 14924)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14924)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 14924)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14924
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.083"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            complement(567..1310)
                     /locus_tag="KRH23_003379"
     CDS             complement(567..1310)
                     /locus_tag="KRH23_003379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HHS5226650.1"
                     /translation="MNFLSDLHTHSIVSGHGYSTLLENINYCKENGIKILGTSEHGPK
                     MPGSPHRWYFHNIQNIPRIINNIIILRGCEANILDIKGNIDLEPFVIPRLDYLILSFH
                     EAVFSPNTLENNTKALINAINKHNNIEILGHLGNPNYPIDYELIIKLAIEKNILIEIN
                     NCSIKGVSRNGSSDNCKYIATLCKKYGAKIILTSDAHICFDIGNYEYSENILKEINFP
                     DELIMNYPKKLINHFHQKDKLLDVDYTNI"
     gene            1476..4043
                     /locus_tag="KRH23_003380"
     CDS             1476..4043
                     /locus_tag="KRH23_003380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54-dependent transcriptional regulator"
                     /protein_id="HHS5226651.1"
                     /translation="MTQKKLSRKEKVLICLKRLTEEHLNFNNGIRFGFDAEYIATEVG
                     INRSNASKELNQLIKESIIIKIKGKPVQYLYKESIESILGKKLNKGIFDNINSINEYS
                     ENDSIKDEYILESIKKENNIFNLVGCDGSLRSQIEQAKAAVIYPPKGLSTLIIGPTGV
                     GKSIFAEYMYKYSLTIKEDSDNAPFIIFNCADYSDNQQLLLAQLFGYVKGAFTGADKD
                     KYGIVHEANNGVLFLDEVHRLSAEGQEMLFLLMDKGIYRRLGEANKVHECRVMIIAAT
                     TEDPETAMLETFLRRIPVTIKIPSLEERGFQERMKLICYFFKEESVRIGVKLKVSKEV
                     IKAFILYKCKGNIGQLKSDIQLICARAFLDYMTYKRECVYVRLSLLPNNIRESLYGNN
                     RKEEFVQNFSFIGKDDIIFLPEEKDFESENLLIENKKYDLDFYGMIKETWNKLQQEGI
                     KESQIRSVIDGDIQKYSYNLMNTFIYNSSNQTAYNNIVNDSIATTVKYILQKHDKWSK
                     REGLDKLIKAIALHIQNLIERIKIGNIVKHPNKDEIMKERAYEYNIAKEILSNMSLMY
                     GVEFPEDEAIFLATFLYLSYVGLNEESIAILVIMHGESTASSMVNVANTLLDCNHAVA
                     INMGLEDRVQDILVQAVEIANKIDKGKGILILTDMGSILTFAKVIRDATGKEVKAIDM
                     VSTPIVIEATRKALTPEMTLEKLYFNIIESIKKHYGDMEVTYAEKDNGGRYFDRLLID
                     NISKTLTFLNGEKAYFILKEVINRISEHYSLVIQDELLVKFIFHCSCMIERVIIKESL
                     VYKSYEERISRNKELYLVIKESFKLVEETFDIIISDMEYANILDIFESQYDTDKFKS"
     gene            4273..4677
                     /locus_tag="KRH23_003381"
     CDS             4273..4677
                     /locus_tag="KRH23_003381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HHS5226652.1"
                     /translation="MIGIIVMTHGSFSEEIIKSCELIAGPAERTAAIKLNRNDNIEDL
                     NKNFVEKLNELDEGDGVLVLADLLGGSPSNVASLNLKKGGKFHALTGVNLPMLLEALI
                     NREGKSLEELAEACIEAGQTGINNINKVLSSM"
     gene            4701..5198
                     /locus_tag="KRH23_003382"
     CDS             4701..5198
                     /locus_tag="KRH23_003382"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HHS5226653.1"
                     /translation="MSLVKYCRCDDRLIHGQVIYKWVKHLGVKKIVVVDDETTNDVIA
                     KGLIKMAAPKNIDLSILTVSESRRYFYNNQADDNVFVLIKNLDTANRMIEEGINIKKL
                     IVGRIPTGIGKKKISQNVYINKKEFLLIDEFIKKNINVSIQMVPDEEKVELNQNINRY
                     KGEFI"
     gene            5201..5602
                     /locus_tag="KRH23_003383"
     CDS             5201..5602
                     /locus_tag="KRH23_003383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HHS5226654.1"
                     /translation="MNKYKVIILCHGTWGKVLVEEINKNFGLSNQYEVLSLSSEKDVS
                     VFMKEVEEVVDKEDVKIIISDLYGGSTSSVAIAVAIRRGIDAINGLSLQTILIVDEEL
                     SKEDKLHTLPERIVKKNNNLCVDLIKEFKKI"
     gene            5620..6108
                     /locus_tag="KRH23_003384"
     CDS             5620..6108
                     /locus_tag="KRH23_003384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HHS5226655.1"
                     /translation="MAKITLVRVDHRLIHGQVITKWVKIAQAQKIIIVDDFLGQDEFM
                     ADIYKMAAPSGVEVVILTAEDAGQAFQNNTLGDKNIFILFKNVDMANKAYKAGLKYEK
                     IQLGGIPNEAGKKMVFTAVSLGNEDVEQLNELNENGVEIVLQVIPEESSMTYENALKK
                     FK"
     gene            6135..6890
                     /locus_tag="KRH23_003385"
     CDS             6135..6890
                     /locus_tag="KRH23_003385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HHS5226656.1"
                     /translation="MESVLMLAIVTGLWYWFAAGLAGYTLFSTLKSPLFIGFSLGLLW
                     GDVTTGMIVGASIEMVYLGMVAAGGNIPSDKCLAALIAIPVALQTGVNAEVAVSIAVP
                     LGVIGVLVNNLRRTGNAVLVHKADKYAEEGNTKGIWRCATLYSLIFGFVLRFPIVFVC
                     NFFGADLVQSLLDVIPQWLMNGLTVMGGILPALGFATTIFTIGKNKFLPMFIIGFFMV
                     QYFEISITAAAIFGVCIALLITFMKEDKRVGEV"
     gene            6890..7753
                     /locus_tag="KRH23_003386"
     CDS             6890..7753
                     /locus_tag="KRH23_003386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HHS5226657.1"
                     /translation="MQEIKNKEVKNGQGPTEVNKTRVLTKKDVTKTYLRWWWTAELSN
                     SFERMQALAVCASFTPALEKLYKRKEDLVDALKRHLQFFNTQAIWGGLIHGTVLAMEE
                     EKATEGKIPGEVISGVKNGLMGPLAGIGDTLDFGTFQTIFLALGASFGAEGSVIGAFF
                     PIMFSILLFCEGYYLFHLGYSLGRDSIKKILSGGIVNKIIDGASILGMFMMGALSATT
                     VKLSTPLSFDIGGKAIVVQDTLNMIAPGLLPLGVVFFVYWGMKYKKWTITKLLVILVV
                     LALVGSFIGIF"
     gene            7800..8279
                     /locus_tag="KRH23_003387"
     CDS             7800..8279
                     /locus_tag="KRH23_003387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-2-amino-thiazoline-4-carboxylic acid
                     hydrolase"
                     /protein_id="HHS5226658.1"
                     /translation="MSEKMYTEKEYLEGIRGATGERAVWFYLLMKEAEKLGANPDDIC
                     KEAIYGFGKMRGQKYNVADTPGKMAEMLYNSKGQKVFEMELVENTDENGVLKFHHCPL
                     DAAWKEYGLTKEERKEICRLACYGDYGRVDCAQGVKLDFAQKCAHDDEVCELVFTKK"
     gene            8344..9651
                     /locus_tag="KRH23_003388"
     CDS             8344..9651
                     /locus_tag="KRH23_003388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HHS5226659.1"
                     /translation="MDISRSVDNSLNRTIEFLKELIKIDSQQGEPISQCPFGIGPKKS
                     LDKTLDYCASLGFSVKNIDNYIGYAEIGEGEELIGIPMHLDIVPPGEGWSVDPFSGAV
                     IDNIIYGRGVIDNKGAVSMLIHVLKNIEDMYPTINKRIRLIFGTNEETGMKCIKYYLD
                     KGEEIPSMGFTPDAMYPVVNGEKGRVHIRIEKEIKIDKSKPYIIVRGGTKENVVPSHC
                     TAKIINGIISELTTKGVAVHASNPEKGENAISKMVIKIVEDNMDFQHREDIELVSKYL
                     CSDYYGDALGINQYDEVFKNTTLNLGILKVNEEKIVCELDIRYGKNIVLNNIIDRFKK
                     VFCNGWKIEVIAHKDLHYVDESNLVLKKLLEAYEEVTDENGYTIAMGGGTYASWFKDM
                     VAFGPKFLAYKTGGHGVDERVPINHIRKNMEIYTLALIKLLEL"
     gene            9979..10101
                     /locus_tag="KRH23_003389"
     CDS             9979..10101
                     /locus_tag="KRH23_003389"
                     /inference="COORDINATES: protein motif:HMM:NF021468.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein Imm33 domain-containing
                     protein"
                     /protein_id="HHS5226660.1"
                     /translation="MLSNKITKECYKIGYMIREKSIDTYPDSGRGFMTWDENGE"
     gene            10611..10748
                     /locus_tag="KRH23_003390"
     CDS             10611..10748
                     /locus_tag="KRH23_003390"
                     /inference="COORDINATES: protein motif:HMM:NF013540.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHS5226661.1"
                     /translation="MNELNIAKTLILKRKEKGITQDELANYIGVSKASVSKWETGGSL
                     R"
     gene            10988..11413
                     /locus_tag="KRH23_003391"
     CDS             10988..11413
                     /locus_tag="KRH23_003391"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226662.1"
                     /translation="MKRQDLKRQENRAVLAWRGAASAGLVSSADRAYMKAPVPRPTLR
                     LVDKVSRSCGHTPGKVAGQRATVKAEMNGVTPGLDRRPPPRWMGGQGGQSLKVLGRAL
                     SDFEVFSFSKLNNQNKFFRLKKFYLLSSSMPYFFFCRIT"
     gene            complement(11362..12228)
                     /locus_tag="KRH23_003392"
     CDS             complement(11362..12228)
                     /locus_tag="KRH23_003392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001255868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 6-adenylyltransferase AadE"
                     /protein_id="HHS5226663.1"
                     /translation="MRSEKEVYDIVLNFAKTDKRIRMVTLEGSRTNTNIPPDDFQDFD
                     ITFFVTDMDSFTSDDKWLDIFGERLILQKPEDMELFPAVEKGFSYLMLFTDDVKIDLT
                     LLPLELIDEYFTWDKLVKLLLDKDNRIVKPPIPTDIDYHLQKPTQRMFDDCCNEFWNT
                     TTYVVKGLCRKEILFAIDHMNDIVRKELLRMISWLIGIKQGFHFSLGKNYKFMKQYVP
                     EELWERLMSTYNMDSYPHMWESFEQCMALFREVSSEVACQLDYQYPLYDEKISNYVIR
                     QKKKYGIEDDNK"
     gene            complement(12402..12803)
                     /locus_tag="KRH23_003393"
     CDS             complement(12402..12803)
                     /locus_tag="KRH23_003393"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226664.1"
                     /translation="MNTAISKGNEWTIAKELELGGYIVSGAYSTDNKSTLAIFEPTGN
                     GDYKFSTSTNRNSDEIIVGGVAINGEWYDLIWFNGAKTEYAEITYTINGQVQDTLRYN
                     TDDMDIISIKNPEKEYSIHVAYYDNDGNKYE"
     gene            complement(12954..13754)
                     /locus_tag="KRH23_003394"
     CDS             complement(12954..13754)
                     /locus_tag="KRH23_003394"
                     /inference="COORDINATES: protein motif:HMM:NF024252.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHS5226665.1"
                     /translation="MELSIQERLKDLRVERGLTLEQLAEQTHLSKSALGSYEGDKFKD
                     ISHYALIELAKFYEVTVDYLLGRSQTKNHPNADLADLRLSDDMIELLKSGRVDNSLLC
                     ELATHPDFPRLMADLEIYVNGVAGKQVQSANAIVDAVSATIMKQHNPGLTDPQLRQLI
                     AAHIDDDSFCRYVIQQDINKIALDLREAHKDDFFSVPEDNPLEDFLQTAEETTSPDSD
                     PEQAAMAFICKRLKLNYGKLSEEEKKWLKKIAQKSDLLKNPKPQRGRK"
     gene            complement(13789..14094)
                     /locus_tag="KRH23_003395"
     CDS             complement(13789..14094)
                     /locus_tag="KRH23_003395"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226666.1"
                     /translation="MKTVTICGSMKFETEMQRIAFLLETKHNMNVLQCVYNVDNLDIT
                     PMEQVSLENAHYRKIELSDAIYVVDIQGYIGNQVSKEIAFAKSKGKKVIFHSAYRGN"
     gene            14549..>14924
                     /locus_tag="KRH23_003396"
     CDS             14549..>14924
                     /locus_tag="KRH23_003396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009298860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich VLP domain-containing protein"
                     /protein_id="HHS5226667.1"
                     /translation="MRDNPYKDLPPLERKPDGSLYRMTPAQKKQAASLIRRECCCFED
                     GNCVVLDDGDTCTCPQTVSFSVCCKWFRWAVLPLYGTLEAEIFRDKDLKRCAVCGGVF
                     VPKSNRAKYCPGCAARVHRRQKT"
BASE COUNT         5280 a         2044 c         2898 g         4702 t
ORIGIN      
        1 tgtatgataa attaaattta aatatttaga gataagctat tatagaattt gcttagttta
       61 agttaaattt taaaatattc aaaaaggggc tagagtctgg aaatttttat ttaaagaata
      121 cacataaaaa tttctagact ctcatcattt aaaagaagta ttctaaattt attatttata
      181 attaaatatt atctgaaaaa atggtatttt tatacctttg tttgttatgc ataattttac
      241 ttagaacata agctttatat aaaataatta aaaatatacc taattaaaat aagtaaagaa
      301 agagctatca tagaacaaat ttaatttgct catgcgacag ctccttttta gatgatgctt
      361 ttttagattt atactataag gtatataaaa ctaagcttat taaaaatgtt ataatttcta
      421 ttgctatcat agaccatatc aatccatcaa gttcataaaa gtaattaagc tttattaaat
      481 agcttcttta ttataatttc tttatttcat ataatataaa tagtattaaa atttttatgg
      541 gagttaaagt aagcatgtat tattacttag atatttgtat aatcaacatc tagtaattta
      601 tctttttggt gaaaatgatt aataagtttt ttaggataat tcattattaa ttcatctgga
      661 aaattaattt cctttaagat attttcagaa tactcatagt tacctatgtc aaaacaaatg
      721 tgagcatctg aagttagtat gattttagca ccatattttt tgcaaagtgt agcaatatac
      781 ttacagttat ccgagctacc atttcttgac acgcctttaa tagaacaatt atttatttct
      841 attaagatat tcttttctat agctaattta atgattaatt catagtcgat tgggtagttt
      901 gggtttccaa ggtgtcctaa tatttcaata ttattatgct tatttattgc atttattaaa
      961 gctttagtat tattctctaa tgtatttgga gaaaaaacag cttcgtgaaa tgacaagata
     1021 agataatcta accgaggaat tacaaaaggc tctaggtcta tgtttccttt aatatctagt
     1081 atatttgctt cacagcctct taaaattata atgttattta tgattcttgg gatattttga
     1141 atgttgtgaa agtaccatct gtggggagaa ccaggcatct taggaccatg ttcagatgta
     1201 cctagtatct taattccatt ttctttacaa taattaatat tttctagtaa agtgctatag
     1261 ccatgaccac tgactataga gtgggtgtgt aaatctgata aaaaattcat ataaattcct
     1321 cctctataaa agatgagggt aacgtaattt atattataaa acgaatagga aagaaaatca
     1381 atagttacat aattagacaa aaatattaaa atattgtaga attaagctta ataataaatg
     1441 tttaacagta ttactgctta taggggaggt taactatgac acaaaagaag ctatcaagga
     1501 aagaaaaagt tttaatttgc ttgaaaaggt taacagaaga acacttgaac tttaataatg
     1561 gcattagatt tggatttgat gcagaatata tagctactga agtaggtata aatagaagta
     1621 atgctagtaa ggaattaaat caattaataa aagaaagtat tattataaag ataaagggta
     1681 agcctgttca gtacttatat aaagaaagta ttgagagtat tttaggaaag aaactaaata
     1741 aagggatatt tgataatatt aactctataa acgaatatag tgaaaatgat tctatcaaag
     1801 atgagtatat tttagagagt ataaaaaaag agaacaatat ttttaattta gtaggatgtg
     1861 atggaagttt aaggtcccaa atagaacagg ctaaagcagc agtaatatat ccacctaagg
     1921 ggttaagtac attaataata gggcctacag gagttggtaa atctatattt gcagaatata
     1981 tgtataagta tagtttaact ataaaagaag atagtgataa tgcaccattt atcatattta
     2041 actgtgctga ttattctgat aatcagcaat tattattagc gcagcttttt ggatatgtaa
     2101 aaggagcatt tactggagct gataaagata agtatggtat tgtacatgaa gctaataatg
     2161 gagtattgtt tttagatgaa gttcatagat tatctgcaga gggacaagaa atgctatttc
     2221 tgcttatgga taaagggata tatagaaggt taggagaggc taataaggta cacgagtgta
     2281 gagttatgat aattgcagcc actacagaag acccagaaac agcaatgttg gaaacgtttt
     2341 taagaagaat acctgtaact ataaagattc cgtctttaga ggaaagaggc tttcaagaga
     2401 gaatgaagct tatatgttat ttttttaaag aagagagtgt taggattggt gttaagttaa
     2461 aggtttcaaa agaagttatt aaggcattta ttttatataa gtgtaaggga aacataggcc
     2521 aattaaaaag cgatatacaa ttaatttgtg caagagcttt tttagattat atgacctata
     2581 aaagggaatg tgtatatgta aggctctctc ttctaccaaa taatattaga gaatcattat
     2641 atggaaataa tagaaaagag gagtttgtac aaaatttcag ttttattgga aaagatgata
     2701 ttattttttt accagaagaa aaggattttg aaagtgaaaa tttattaata gaaaataaaa
     2761 aatatgattt agatttttat ggaatgataa aagaaacttg gaataaactt caacaagaag
     2821 gtattaaaga gtcacaaatt agaagtgtta tagatggaga catacagaag tattcctata
     2881 atttaatgaa tacttttata tataatagta gtaatcaaac agcttataac aacattgtta
     2941 atgattcaat tgcaactact gtaaaatata ttttacaaaa gcatgataaa tggagcaaaa
     3001 gagaaggatt agataaatta ataaaagcta tagctttaca tattcagaat ttaattgaaa
     3061 gaataaagat tggaaatata gtaaagcatc ctaataaaga tgaaattatg aaggaaagag
     3121 catatgaata taacatagca aaagaaatat tatctaacat gtcattaatg tatggagtag
     3181 agtttccaga agatgaagca atttttttag caacatttct ttatttatcg tatgtgggat
     3241 taaatgagga gagtatagca atattagtca taatgcatgg tgaatctaca gcatctagca
     3301 tggtgaatgt agccaatact ttactggatt gtaaccatgc agtggcaatt aatatgggat
     3361 tagaagatag agttcaggat attttagtac aagctgtaga aatagccaat aaaattgata
     3421 aaggaaaggg aattttaatt ttaactgata tggggtctat tttaacattt gctaaagtta
     3481 ttcgtgatgc tacaggaaaa gaagtaaaag caatagatat ggtaagtaca cctattgtaa
     3541 tagaagcaac tagaaaggct ctaactccag aaatgacatt agagaaatta tattttaata
     3601 ttatagaatc tataaagaaa cattatggag atatggaagt tacatatgct gaaaaagata
     3661 atggtggtag atattttgat agactactaa ttgataatat tagtaaaact ttgacttttt
     3721 taaatgggga aaaggcttat tttatattaa aagaagtaat taatagaatt agtgaacact
     3781 attctttagt aattcaagat gaacttttag taaagtttat atttcattgt tcatgtatga
     3841 ttgaaagagt aataataaaa gagtctttag tttataaatc atatgaagaa agaattagta
     3901 gaaataaaga attatattta gttataaaag aaagttttaa gctagtagaa gagacattcg
     3961 atataattat ttcagatatg gaatatgcaa atatattaga tatatttgaa tcacaatatg
     4021 atacagataa attcaaaagt tgatacaaaa tttaaaaata gccaaaaggc tatctttttt
     4081 ttactttttt tgatacagat ttgatacagg ttgaaaaaat cttttgatac atatcgaaat
     4141 aataagtttt taaaaaaaat tgagtaaaaa gttttgatta aatcctgtaa aatagccatt
     4201 tgttattgat acacataagt tggcacggca attgcttata taaaaagtga caagaaaagt
     4261 gaggtgaaat tggtgatagg aataatagtt atgactcatg ggagttttag tgaagaaatt
     4321 ataaaaagct gtgaacttat tgcaggacca gcagaaagaa cagcagcaat taaactaaat
     4381 aggaatgata atattgaaga cttaaataaa aattttgtag aaaagttaaa tgaattagat
     4441 gaaggtgacg gagttttagt attagctgac ctattaggag gttcgccaag taatgttgca
     4501 agtttaaacc ttaaaaaagg tggcaagttt catgcactta ctggagtaaa tcttccaatg
     4561 ctacttgaag ctttaattaa tagagaggga aaaagtttag aagagttagc agaagcatgt
     4621 attgaagcag gacaaactgg tataaacaat attaataaag ttcttagctc aatgtaatag
     4681 aaaaaggagt ttgattaaaa atgtctttag taaaatattg cagatgtgat gatagattaa
     4741 tacatggtca agttatatat aaatgggtta agcatctagg tgtaaaaaag atagtagtag
     4801 tagatgatga aacaaccaat gatgttattg ctaaaggttt gataaaaatg gcagcaccaa
     4861 agaatattga tttatcgata ttaactgtaa gtgaatcaag gagatatttt tataataatc
     4921 aagctgatga taacgttttt gtattaatta aaaatttaga tactgcaaat agaatgatag
     4981 aagaagggat taatatcaaa aaacttattg ttggaagaat acctacagga ataggaaaaa
     5041 agaaaatatc tcaaaatgta tacattaata aaaaagagtt tcttttaata gatgaattta
     5101 ttaaaaagaa tattaatgta tcaattcaaa tggtacctga tgaagaaaaa gtagaattaa
     5161 accaaaatat taatcgctat aaaggagagt ttatttagca atgaataaat ataaggtaat
     5221 catactgtgc catggaactt ggggaaaagt cttagtagaa gaaataaata aaaactttgg
     5281 attgtcaaat caatatgaag ttttatcact aagttctgaa aaagatgttt ctgtatttat
     5341 gaaagaggtt gaagaagtag tagataaaga agatgtgaaa attataatat cagatttata
     5401 tggaggatct acatcaagtg tcgcaatagc tgttgctata agaagaggaa tagatgcaat
     5461 aaatggactt agcttacaga caattttaat cgtagatgaa gaattaagca aagaagataa
     5521 attacataca ttaccagaaa gaatcgtcaa aaaaaataat aacctttgtg tggatttaat
     5581 taaagaattt aaaaaaatat aaattatgag gtgaatataa tggcaaaaat aacattagta
     5641 agagtagacc acagattaat tcatgggcaa gttataacaa aatgggtaaa aatcgctcaa
     5701 gctcaaaaaa taataatagt tgatgacttc ttaggtcaag atgaatttat ggctgacata
     5761 tataaaatgg cagcaccatc aggagtagaa gtagttattt taacagcaga agatgcggga
     5821 caagcattcc aaaacaacac tttaggagat aaaaatatat ttattctatt taaaaatgtt
     5881 gatatggcaa ataaggctta taaagctgga cttaaatatg aaaagattca attaggaggt
     5941 attccaaatg aagcaggaaa gaagatggtg tttacagctg tttcattagg aaatgaggat
     6001 gtagaacaac ttaatgaact taatgaaaat ggggttgaaa tagtcctaca agttatacca
     6061 gaggaatcat ccatgacata tgaaaatgcg ttaaagaaat ttaaataaaa aatataaatt
     6121 aggaggaatt ataaatggaa tctgttttga tgttggcaat tgtaacagga ttatggtatt
     6181 ggtttgcagc aggtcttgca gggtataccc ttttctcaac actaaagtct cctttattta
     6241 taggttttag ccttggatta ctttggggtg atgtaacaac tggtatgatt gttggtgcaa
     6301 gtatagaaat ggtttatcta ggaatggtcg cagcaggggg aaatattcca tcagataaat
     6361 gtctagctgc tcttattgca ataccagtag cacttcaaac tggtgttaat gcagaagttg
     6421 cagtatctat tgcggtacct ttaggtgtta taggagtatt agttaataac ttaagaagaa
     6481 ctggtaatgc tgtattggtt cataaggcag ataaatatgc tgaagaaggt aatacaaaag
     6541 gcatctggag atgtgcaaca ctttattctt taatatttgg gtttgtctta aggtttccaa
     6601 tagtttttgt atgtaacttt tttggagcag atttagttca atcattatta gatgttatac
     6661 cacaatggtt aatgaatgga ttaacagtaa tgggcggtat attacctgca ttaggttttg
     6721 caacaacaat atttactata ggtaaaaata aattcttacc aatgtttatt ataggatttt
     6781 ttatggttca atattttgaa atatcaatta ctgcagctgc aatatttggt gtttgtatag
     6841 ctcttttaat tacctttatg aaagaagaca aaagggtagg tgaagtataa tgcaagaaat
     6901 aaaaaataaa gaagttaaaa atggacaagg tccaactgaa gttaataaga caagagtact
     6961 tacaaagaaa gatgtaacaa aaacatatct aagatggtgg tggacagcag aattatccaa
     7021 ctcttttgaa agaatgcaag cattagcagt ttgtgcaagt ttcactccgg ctttagaaaa
     7081 gttatataag agaaaagaag atttagtaga tgcgttaaag agacacttac aattttttaa
     7141 tactcaagct atatggggag gattaattca cggtacagtt ttagctatgg aagaagagaa
     7201 agctactgaa ggaaaaatcc caggagaagt tatttcaggt gttaagaatg gtcttatggg
     7261 acctttggct ggaattggag atactttaga ttttggtaca tttcaaacaa tattcttagc
     7321 tttaggtgct tcatttggag cagaaggaag tgttataggt gcatttttcc caataatgtt
     7381 tagtatatta ctattttgcg aaggttatta cttatttcat ttaggatatt ctttaggtag
     7441 agattcaatt aagaaaattc tatcaggtgg tattgtcaat aagataattg atggtgcttc
     7501 aattctagga atgtttatga tgggagcatt atctgcaact acagttaagc tttcaactcc
     7561 gctatcattt gatattggtg gtaaagcaat tgttgttcaa gatacattaa atatgattgc
     7621 tccaggttta ttaccacttg gtgttgtatt cttcgtatat tggggaatga aatacaagaa
     7681 gtggacaata actaagttat tagtaatttt ggttgtatta gcattggtag ggtcattcat
     7741 tggaatattc taattcacag tgattaaaat atagaattta attttaggag gagaaagaaa
     7801 tgtcagaaaa aatgtataca gaaaaggaat atttagaagg aattagagga gcaacaggag
     7861 aaagagcagt atggttctat cttcttatga aagaagctga aaaattagga gctaatccag
     7921 atgatatatg taaagaagca atatatggat ttggtaaaat gagaggtcaa aaatataacg
     7981 tagcagatac tccaggaaaa atggcagaaa tgttatataa cagtaaagga caaaaagtgt
     8041 ttgaaatgga attagtagaa aatacagatg agaatggcgt tttaaaattc catcactgtc
     8101 cattagatgc tgcttggaaa gaatatggat taactaaaga agaaagaaaa gaaatttgta
     8161 gattagcttg ttatggggat tatggaagag ttgactgtgc acaaggtgtt aaattagatt
     8221 ttgctcaaaa atgtgctcat gatgatgaag tttgtgaatt agtatttaca aaaaaataat
     8281 ttttaatgct aaaagcctgt tctttaagga caggctttaa aaagatagaa agtaggttga
     8341 tttatggata taagcagaag tgtagataat agtttaaata gaaccataga atttctaaaa
     8401 gaattgataa aaattgattc acaacaaggt gaacctattt cacaatgtcc ttttggtata
     8461 ggacctaaaa aatctttaga taaaacttta gattactgtg ctagtttagg ttttagtgtt
     8521 aaaaatattg ataattatat tggatatgca gaaattggag agggagagga attaataggg
     8581 attccaatgc atttagatat agttccacca ggagaggggt ggagtgtaga cccattttcg
     8641 ggagcagtaa ttgacaatat tatttatgga agaggtgtca tagataataa gggtgctgta
     8701 tctatgctta tacatgtatt gaaaaacata gaggatatgt atcctacaat taataaaaga
     8761 ataagattaa tttttggtac aaatgaggaa acaggtatga aatgtatcaa atattactta
     8821 gataaaggtg aagaaattcc aagtatggga tttactccag atgctatgta tccagtggtt
     8881 aatggagaaa aaggaagggt tcatataagg atagaaaaag aaattaaaat tgacaaaagt
     8941 aaaccttata taatagtaag gggaggaact aaagaaaatg ttgttccatc tcattgtact
     9001 gcaaaaatta ttaatggaat tatttcagag ttaactacta aaggagtagc tgtacatgca
     9061 agtaatcctg aaaagggaga aaatgctata tctaaaatgg taataaagat agttgaagat
     9121 aatatggatt ttcagcatag agaagatata gaattagttt caaaatatct ttgtagtgat
     9181 tattatggag atgcattggg gattaatcaa tatgatgagg tattcaaaaa cactacctta
     9241 aatttaggaa tattaaaagt aaatgaggaa aaaatcgtat gtgagttaga tataaggtat
     9301 ggtaaaaata tagttttaaa caatataata gatagattca aaaaggtttt ttgtaatggt
     9361 tggaaaatag aggttattgc tcataaagac ttacattatg tggatgagag taatttagta
     9421 cttaaaaaat tattagaagc ctatgaagaa gtaacagatg aaaatggata tacaattgct
     9481 atgggtggtg gcacatatgc aagttggttt aaagatatgg tggcgtttgg acctaagttc
     9541 ttagcgtata aaactggtgg tcatggagta gatgaaagag taccaataaa tcatatacga
     9601 aagaatatgg agatatatac tttggcttta ataaaactat tagaattgta aaagaagaag
     9661 agactttatg tgcaaattta cggatatctt aaaaagagag ataaaacgag ttcaacctta
     9721 tttaaatgtt caacaccatc aaatggggct gtctcaaaat agagataagc ctcttactta
     9781 ttgttgaaat gatgaaaata tattttactt tatacaaaaa agagtgcctt atgaagtaaa
     9841 aagttaattt tgagacaccc tcatttgatg atgttgaaga gaaaataagt atgaaattat
     9901 taaaaaagat gattttataa aagttaaggt tgaaaagaaa agttaattaa atggaattag
     9961 ataaatggag aaggctgtat actatctaat aaaataacaa aagagtgtta taaaattggt
    10021 tatatgatta gagaaaagtc tattgatact tatccagata gtggacgggg atttatgact
    10081 tgggatgaaa atggagaata ataaaaatta tagtttatac agtttaataa gatatatgta
    10141 caagcagtta atctaaatga ttgactgctt ttcttttata gatttttata taatagacaa
    10201 ataccaatac atgatagttg actgttataa ttagaggaat aaatacgaat aataacttta
    10261 taaaagaatt aaatggaaaa tcgaagagtt atattcagta ttttaaaaag aatatgaaat
    10321 gagaaatgaa aataaggtgt ttatattaaa agaggtttta tacaaaatat ttaaaaacgt
    10381 gataaataaa aactgtattt agatagatta actattagtt ttatataata tggattttat
    10441 ttacaaattt tacatatttt acaaaagaga ttaaagataa atttaaatat atattttata
    10501 tacttgttta tttgtttctc tgtggttgat tttttcgtca aaagtcaact tcaaatcgct
    10561 tgttagcttt acatgtttaa ggatataatt atacataagg agggattgac atgaatgaat
    10621 taaacatcgc aaaaacgctg attttaaagc gtaaagaaaa aggaattaca caagatgaac
    10681 ttgcaaatta tataggcgtt tctaaagctt ctgtatctaa atgggaaact gggggttcac
    10741 ttagataaag ataccacacc aatcccacgc tgacttttgc tcaaccaata cagccggagg
    10801 gctggataac aagaaaaggc ggtatgcgcc ccgtggaggg gtagcatatc gccttttctt
    10861 gtgggggttt ccaaaggggg caacgccccc atttggcaca cgactttgcg aagcaaagtg
    10921 tagtgtgtta tacgctctgt cggcgttgtc gtgaaaatgc cgttgccgcc ggggagggca
    10981 agggcatttg aagcggcaag atttgaagcg gcaagaaaac agggctgtgc ttgcgtggcg
    11041 tggagccgca agcgcaggtc tggtttcatc agcagacaga gcgtatatga aagcccccgt
    11101 ccctcgtcct acgctccgac ttgtggacaa agtgtcccga agttgtggcc acactcccgg
    11161 aaaagtagca ggacagcggg caaccgtcaa ggctgaaatg aacggggtta cacccggcct
    11221 tgaccgccgc ccgccgcccc gctggatggg tggacaaggc ggccaatccc tcaaagtgct
    11281 tggccgcgct ctttctgatt ttgaggtatt cagtttttca aaattgaata atcaaaataa
    11341 attttttcga ttgaaaaaat tttatttgtt atcatcttca atgccatatt ttttcttttg
    11401 ccgaatcaca taattactga ttttttcatc atatagtgga tactggtaat ccaactggca
    11461 tgccacttct gacgaaacct cccggaacaa tgccatacat tgttcaaagg attcccacat
    11521 atggggatag gaatccatat tataagtgga cataagtcgt tcccacaatt cctctgggac
    11581 atattgcttc ataaatttat agttttttcc caaactgaaa tgaaatccct gtttgatacc
    11641 aatcagccag gaaatcatgc gaagcaattc ttttcgtact atatcattca tatggtcaat
    11701 agcaaaaaga atttctttgc ggcataagcc ctttactaca tatgttgtag tattccaaaa
    11761 ttcattacag caatcgtcaa acattctttg agtaggcttc tgcaagtggt agtctatatc
    11821 cgttggtatt ggcggcttta cgatacggtt gtctttatcc aacagtaact ttaccagttt
    11881 atcccatgta aaatactcgt ctatcagttc cagcggcagc aaagttaaat ctatcttaac
    11941 atcatcagta aacagcatta aatatgaaaa tcccttttct acagctggaa ataattccat
    12001 atcttccggc ttttgcagaa tcaacctttc accaaatata tctagccatt tatcatcact
    12061 tgtgaagctg tccatatccg taacaaaaaa agtaatatca aaatcctgaa aatcatcagg
    12121 cggaatattt gtatttgttc tagatccttc caaagtaacc atgcgaatgc gtttgtctgt
    12181 ttttgcaaaa ttcaaaacaa tatcataaac ttccttttct gatctcattt ttatctcctc
    12241 caattattga aataggtgtg aagccatttt agggctttcc cgccttgatt accctttagc
    12301 aaagacgggc gggactgtca acggcggcgc atgaaatgcg ccgttcatct tgaccgttga
    12361 ctggctcggc tggctttgct attttctcga tgaaaaacaa tttattcgta tttatttcca
    12421 tcattgtcat agtaagccac atgaatggaa tactcttttt ctgggttttt aattgagata
    12481 atatccatat catctgtgtt gtatctcaat gtatcttgca cttgtccatt tattgtataa
    12541 gtgatttcag catactctgt tttagcacca ttaaaccaaa ttaaatcata ccattctccg
    12601 tttattgcaa cgccaccgac aataatctca tcactatttc ggtttgttga tgtactaaat
    12661 ttgtagtctc catttcctgt tggttcaaag atagcaagtg tagatttatt atctgtactg
    12721 tatgctccac tcacgatata accgccaagt tccagttctt ttgcgatagt ccattcattc
    12781 ccttttgaaa ttgcggtgtt caatatgctt tctctgctgg taatggtatc tcttttggga
    12841 gttaaactaa agaaatataa aaaagcggca gcaacgcaaa taacagtcgc tgaaattatc
    12901 agtaaccact ttttcataac caatacctcc atataatctg atttattatt ctcttacttg
    12961 cgtccccgct gcggctttgg atttttcagc aaatccgatt tctgtgcaat ctttttcaac
    13021 cacttctttt cttcctctga cagtttccca tagttcagct tgagccgctt acagataaat
    13081 gccatagccg cctgctccgg gtcgctgtcc gggctggtgg tttcctctgc ggtctgcaag
    13141 aaatcttcca gtgggttgtc ctccgggaca ctgaaaaaat cgtccttatg ggcttcccgc
    13201 aggtcgaggg ctatcttgtt tatatcctgc tgtatcacat agcggcaaaa gctgtcgtcg
    13261 tcaatatggg cggcgataag ctgccttaac tgcgggtcag tcaagccggg attgtgctgt
    13321 ttcataatcg ttgcactcac agcgtccaca atggcgtttg cactctgcac ctgctttccc
    13381 gctacgccgt tcacatagat ttcaaggtcg gccatgagcc ggggaaaatc cgggtgggtc
    13441 gccagttcac acaaaaggga attgtccacc cgcccgcttt tcaatagttc aatcatatcg
    13501 tcgctcaaac gcaggtctgc aagatcggcg tttgggtgat tttttgtttg ggagcggccc
    13561 agcagataat caacggtcac ttcataaaac tttgccaact caataagggc atagtggctg
    13621 atgtctttga acttgtcccc ctcataactg cccaaagcag acttggagag atgggtctgc
    13681 tccgcaagtt gttccaatgt cagcccacgc tccacacgca ggtcttttag ccgttcctgt
    13741 atggataact ccatgctctc cctccttgtt tgttcaataa acgggaaatt aatttcctct
    13801 gtatgccgaa tgaaaaatga ctttctttcc tttacttttt gcaaacgcaa tttcttttga
    13861 aacttgattt ccaatgtatc cttgaatatc cacaacataa attgcatcgg agagttcgat
    13921 ttttctataa tgcgcatttt caagagagac ctgttccata ggtgtaatat ccaaattatc
    13981 tacattatat acacattgta aaacattcat attatgtttt gtttctaaca gaaatgctat
    14041 cctttgcatt tctgtttcaa atttcatact tccacatatt gtaactgttt tcatcctgca
    14101 cctcgttcaa tttcgatttg tcgttccgtt gtttccattc taccacaatt ccgagagcgt
    14161 ggaaataggg agttttccgg acggatttcc tacctcttgg atatacggga cgggcggtca
    14221 tttaggtgta gacttagggt agttcatcga tggacagcac cttgaaaaca gaatgaccgt
    14281 ccgaaaaggg ataccccggc tggggaagca ccgcaaggag ccggacttcg ggacaattgt
    14341 cccgaagttg cggggagcgt gcctcgtcgc cgcaagctgc gtatcattcg cttccgccag
    14401 atggcgaaag ctcactcgct ccgctgcggc tcctctcccc acaaagtctg acgactttgc
    14461 gggggcccct gttgggaaca cgccgcagga atggggcagg aaaccttttc ggggagaacg
    14521 gcaacggaaa gcaaaatgga gggaacgcat gagagataac ccctataaag acttgccgcc
    14581 gctggaacgc aagccggacg gttcccttta ccgcatgaca ccggcgcaga agaaacaggc
    14641 ggccagcctg atacgccggg agtgctgttg ctttgaggac ggcaactgcg ttgttcttga
    14701 cgatggggac acctgcacct gcccgcagac ggtttctttc tcggtctgct gtaagtggtt
    14761 ccgctgggcg gttttgccgc tgtacgggac gctggaagcg gagattttcc gggataagga
    14821 cttgaaacgc tgtgcggtct gcggcggtgt gttcgtcccc aaatccaacc gggcaaaata
    14881 ctgccccggc tgtgccgcca gagttcacag gcggcagaaa acag
//
LOCUS       DAEORM030000081        13645 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.084, whole genome shotgun sequence.
ACCESSION   DAEORM030000081 DAEORM030000000
VERSION     DAEORM030000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 13645)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13645)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 13645)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13645
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.084"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            complement(225..1892)
                     /locus_tag="KRH23_003397"
     CDS             complement(225..1892)
                     /locus_tag="KRH23_003397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside kinase"
                     /protein_id="HHS5226668.1"
                     /translation="MKKINLKIEGKDKEYSLEENSPGIRLGDIAKEFCDEHKGYITLA
                     VVDNKLKELNCRVKKDCEINFLDTTNEDGERVYFRVMSFIFVMACREIFWDSRVTIEH
                     SLSDGLYCEVHIDRKLKEADVENIKNKMKEIVNNDYVIEKIEVTRNEAISIFENNEMY
                     EKAELLKYKEYDSAKVYKCRNYIDHFYGYMLPSTGYIKSFDIKLYNGGVIILGPSEED
                     KTLPMKFVPQPKLSSVYYEAEEWSRLMGIDKVVSLNKIIENNEYGDIIRTFEALHEKK
                     LSQIADMIKDGNKRVVLIAAPSSSGKTSFAHRLSIHLRVNNLNPISISLDDYFIDRKH
                     TPLDEYGNYDFESIYAIDLEKFNLDLKKLLAGEEIDDIRFNFKEGKREYTGKKIKIDS
                     NQPIILEGIHGLNPILTSSIPDEDKFKIYISALTQINLDDHNRIPTADLRMIRRIVRD
                     YNFRGYSADNTILQWASVRRGEKKNIFPYQEEADAIFNSACVYELAVLKRFAKPLLEE
                     IKEDNPAHIEATRLLKFLQYFVELDDTSDIPGISILREFIGGSKIVD"
     gene            complement(1966..2721)
                     /locus_tag="KRH23_003398"
     CDS             complement(1966..2721)
                     /locus_tag="KRH23_003398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase family
                     protein"
                     /protein_id="HHS5226669.1"
                     /translation="MAVGIASLLFNIEEALNICESIKQITHLEIGIDNISECSELCKY
                     KERISKLGLSIGIHLPMELNTCENIEYIRNSWINFIEKIEFELKGFDLRYFNLHLGYV
                     MTNRVRKNRDKYLGNSVDFLDKLNTNSYVCIENTYSKGGDFSNIGNISYDFEYIFKRI
                     KNSKICFCYDTGHCLIDEDAYVKNLKDKIRLIHLSDNDGINDTHVGIGRGILSEEGIK
                     EVLTLDAEYLVLEINYEDIEDTISKLNNIVGEG"
     gene            complement(2731..3267)
                     /gene="lepB"
                     /locus_tag="KRH23_003399"
     CDS             complement(2731..3267)
                     /gene="lepB"
                     /locus_tag="KRH23_003399"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HHS5226670.1"
                     /translation="MNETIKEEIVEWIKIIITALFFAFIITRFIKPTLVNGESMYPTL
                     KSHDYLVANRMTYKLSEPKCGDIMIFKTDLLQENGRKKELVKRVIGVPGDHLKIKDSK
                     VYINGKLLNEVSYIHDNYTEGDIDMVIPKGKVFAMGDNREVSLDSRYKEVGLVDEENI
                     KGKVILRVFPFTDIGIFE"
     gene            complement(3433..3969)
                     /gene="lepB"
                     /locus_tag="KRH23_003400"
     CDS             complement(3433..3969)
                     /gene="lepB"
                     /locus_tag="KRH23_003400"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HHS5226671.1"
                     /translation="MGEAVKKEVVEWIKVIVIALVLAFAITRFIVPTIVKGESMYPTL
                     VERDYLIVNRIAYKVGEPKYKDIIVFKTDLTEENGKKKDLVKRVIGVPGDHVKIQDSK
                     VYVNDKLLDETSYIHNNRTDGDIDIVVPEGKLFAMGDNREKSLDSRYDEVGLVDEHTI
                     LGKVLVRLYPFSKIGTID"
     gene            complement(4069..5379)
                     /locus_tag="KRH23_003401"
     CDS             complement(4069..5379)
                     /locus_tag="KRH23_003401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HHS5226672.1"
                     /translation="MTELPKEFLEDIEEILKDEYDDFIKSYEESKTTGLRINTLKIDK
                     KKLFDLELFDLNQIPWAEEGFYYDDKIDRPGRNPLHEAGAYYLQEPSAMSVIPKADIK
                     EGEKVLDMCAAPGGKSTYILSKLNDTGLLVSNEINASRIKALGENLERFGARNCIITN
                     TDSNSLRKTFNGYFDKVIIDAPCSGQGMFRKDEVAISDWSYAKVVECQSIQKEIIRDG
                     YKMLKKDGILIYSTCTFSREENEHVINEFISEYPHAELIEMERLWPHKIKGEGHFVAK
                     IKKLEEEECNVKELKIKNLDKEIKDYREFEKKFLKVDFYSNKKNKFYLRGENLYLLPE
                     IYPDTKKLKVLRYGLHLGVLKKNRFEPSHALSHYLKVEDVKNVENFSVQSESILKYLK
                     GDVVNSNDSRGWVLVSVEGIPLGWGKESSGVIKNHYPKGLRKVF"
     gene            complement(5458..6174)
                     /locus_tag="KRH23_003402"
     CDS             complement(5458..6174)
                     /locus_tag="KRH23_003402"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HHS5226673.1"
                     /translation="MKLDLFLLAIVPILIGMFWIRSKDRYCREPLIHLIKFFLIGAFL
                     SVIIILLENLLMKFNVFEGYSELIYVSFVVAGLVEEGVKALILIPALIKEKHFTEKLD
                     GIIYSVFLALGFATIENMVYIFSESRNLALQVGINRAVISIPAHVMFAITMGYYISKY
                     KFEGNKNKRREYLFMAVLIPILLHGVFDFILMIEYRWAIILLIVYVIILWKINLDKLE
                     KYMNHSKKVFFGNLRKKKKK"
     gene            6419..7690
                     /gene="sleC"
                     /locus_tag="KRH23_003403"
     CDS             6419..7690
                     /gene="sleC"
                     /locus_tag="KRH23_003403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore cortex-lytic germination protein SleC"
                     /protein_id="HHS5226674.1"
                     /translation="MQDGFLTVSIIDATNNRPIQNAVVNIYSMSNGSQSSSTLYQNLR
                     SNESGQVTGLVLPAPDVDYSLQPSDVRPYSQYIVEAIADGYETVVIEGTQLLATIEAR
                     QGVPMSPRTRSKRSFSRQSELIFDIGEHTLYGTYPPKIPESNLKPLPPPTGFVVLDNP
                     VVPEFIVVHDGLPEDSSAPNYWIPFKEYIKNIASSEIYSTWPEQTIYANVIAIISFTL
                     NRVFTEWYRNKGYNFTITSTTAYDHKFINNRNLFEPINVVVDAIFNTFIKRPPTSRQP
                     LLAQYCDGQKSQCPDQMTQWGSKDLGDQGYDYESILRYFYGDEIVFERAPIVSGVPVS
                     FPGTTLQVGSSGQYVRTIQNQLNAISNSYPAVPKVIEDGIYGTDTENAVKIFQGIFGL
                     PQSGVVDFKTWYEISRVYVATTRIASLNPLI"
     gene            complement(8198..8854)
                     /locus_tag="KRH23_003404"
     CDS             complement(8198..8854)
                     /locus_tag="KRH23_003404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226675.1"
                     /translation="MKKGDFIWSGVLICIIAVLAIPSSREVFMEATGAHPYIGGFLKF
                     AVLATMGDLLGARILYKDWKIPVGVFYRAIVWGIIGVVTTYGMSIYSSGVGQAQVDGM
                     LPFEGIAFANALFKSATMNILMSPTVFLFHKVMDCFIDKKYEVGKGIKVKLKDVVNIV
                     DWNAYLGFSVLKTIPFFWIPCHTIVFLFPAEYRVIASAFASIALGLILALANKSKVAV
                     "
     gene            complement(9966..10376)
                     /locus_tag="KRH23_003405"
     CDS             complement(9966..10376)
                     /locus_tag="KRH23_003405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226676.1"
                     /translation="MKIKKSLISAMMVSAMVLGGTGAVFANGNDSSNIALPKFESLIK
                     SGITDPTELEKYGVEHYTYEEYAKHIQELKEYAKDPNAVKDVSQKDLEETIKKMEQEL
                     EKIKTEGLKIMKPITIENEDGSQISIAYNYAAID"
     gene            complement(10592..11974)
                     /locus_tag="KRH23_003406"
     CDS             complement(10592..11974)
                     /locus_tag="KRH23_003406"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M56 family metallopeptidase"
                     /protein_id="HHS5226677.1"
                     /translation="MFIKLLEMSFTSGVLLLIVIFIRACLFKKLPKKVFVLLWLIVLF
                     KLLIPVSLNSGFSIYSIIESTFDVELGNTSTENYTLKKASDSTGKNNSDEFEIMSNIE
                     NIMMLEMLGILSFIVTIMFSILLCFRYFKIINLFKTSIHIKNHEFIKKWMCKNSRFRR
                     FIVCISEFTRTPLTSGILKPRIILPKQMNYANNQTLDFVLTHEMVHINSFDNLLKLFM
                     LVALVVHWFNPLVWVMFFLLNKDIEFSCDEKVMSILGEEYRADYATTLISLAEENNPF
                     SMTICSGFGKTKIEKRIVNIMKFKKSTYVTFLVSTVLVCGTGLVFATENKEINEVESF
                     GLTKNEQSDKIGFSISSKSTDLYSPKVESDILVSKAKSDGETHFSTAKVSVIEFREHE
                     ESSMSKVTNSENSEETYVNKSSNSKDVLYTDSGEVSIERSGYNDNRFVISRKGNLLAV
                     NKEQYRTWIE"
     gene            complement(11985..12344)
                     /locus_tag="KRH23_003407"
     CDS             complement(11985..12344)
                     /locus_tag="KRH23_003407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HHS5226678.1"
                     /translation="MEIKLFDSELKVMEVLWERGESKAGELVKILKEETGWNRNTTYT
                     VIKKLVSKGAIERIEPNFVCKALISKEEVQKQETETLINKMFGGSSEKFLSAFINKEN
                     LSSDEITKLKQIVEKLK"
     gene            complement(12549..13328)
                     /locus_tag="KRH23_003408"
     CDS             complement(12549..13328)
                     /locus_tag="KRH23_003408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HHS5226679.1"
                     /translation="MVSRQELKRVSKAQLSGNWGICAISMAVYIALIVLISIVGLPFE
                     PLTTIVVAVIAFCVSAGFTCMFLKITKDEKVKIGDIFVSGRIYLRSFGFYLFESIIVY
                     IYSFIITIIGAFLSFGVLLTSGAIEYLSSDNVGIGTIISTGITLVLIILVLMLPVYIL
                     LLYVSQATFLICEDKDNMGVFKSMGASLDMMKGNVLKLFVLNFSFIGWYILSIATLGI
                     GLLWLIPYVGVTNCNFYRQLVKENPDVEDILLDKEKSYTMY"
BASE COUNT         4665 a         2446 c         1341 g         5193 t
ORIGIN      
        1 aaaataatca cataaattaa caaaatatta aacaaaaaag taaaatttaa aataaaaagc
       61 ttgcttcata caaaagtata aaacaagcct ttttatatat caactcaaac tttaaaatct
      121 gtatcaattt aattctccac tttacactta atatacttaa cataaaccaa tcacactact
      181 tgctatgcca tttaatcttc ataaaacaat ctataataca cacattaatc aactatttta
      241 cttcctccaa taaattccct aagaattgaa atacctggta tgtcagaagt atcgtccaat
      301 tcaacaaaat actgcaaaaa ctttagtaat ctagtagctt caatatgtgc aggattatct
      361 tcctttatct cttccaacaa aggtttcgca aatcgtttta aaactgccaa ttcatataca
      421 caagcagagt taaatatagc atctgcctcc tcttggtacg ggaatatatt cttcttttct
      481 cctcttctaa ctgatgccca ttgtaaaata gtattatcag cactatatcc tctaaaatta
      541 tagtctctaa caattcttct tatcattctc aaatcagcag tagggattcg attatggtca
      601 tccaaattta tttgagtaag ggcacttatg tatatcttaa atttatcttc atctggtata
      661 gatgatgtta aaataggatt tagcccatgt ataccttcta atataattgg ctgatttgaa
      721 tctatcttta tctttttacc agtgtattct ctcttacctt ctttaaaatt gaatcttata
      781 tcatcaattt cttcaccagc taaaagtttc tttaagtcta agttaaactt ctctaaatct
      841 attgcataaa ttgattcaaa atcataattt ccatattcat ctaaaggagt atgttttcta
      901 tctataaaat aatcatctaa agaaattgaa ataggattta aattatttac tctaagatgt
      961 attgataatc tgtgagcaaa acttgttttt ccagatgaag atggagctgc tattaaaact
     1021 actctcttat tgccatcctt tatcatatct gctatttggg ataacttctt ttcatgcaat
     1081 gcttcaaatg tccttattat atctccatat tcattgtttt ctattatttt attaagagat
     1141 actaccttgt caattcccat aagtcttgac cattcttctg cttcataata tacacttgat
     1201 agcttaggtt gaggtacaaa tttcatagga agagtcttat cttcttcact aggtcctaaa
     1261 attataacgc ctccattata aagcttaata tcaaatgatt ttatataacc agttgatggc
     1321 aacatataac cataaaaatg gtctatatag tttctacact tatatacttt agcactatca
     1381 tactctttgt atttcaaaag ctctgccttt tcatacattt cattattttc aaagatagaa
     1441 atagcttcat ttcttgtaac ttcaattttt tctataacat aatcgttgtt tactatctct
     1501 ttcattttgt tttttatatt ttcaacatct gcttctttaa gctttctatc tatatgaact
     1561 tcacaatata gcccatctga tagtgaatgt tctattgtaa ctctgctatc ccaaaagatt
     1621 tctctacatg ccattacaaa tataaatgac atgactctaa agtaaactct ctctccatct
     1681 tcattagtag tatctaaaaa atttatctca caatccttct taactctaca atttagctct
     1741 tttagtttat tgtctacaac tgcaagtgtt atataaccct tatgctcatc acaaaattct
     1801 tttgctatat ctcccaatct gattccaggg gaattttctt ctaatgaata ttccttatct
     1861 tttccttcta tttttaagtt tatttttttc acttcaacat ctccttcctt ttgatgaata
     1921 taaattttaa ttaatgaggc atatcaacaa gataaagaga ggtatttaac cctctcctac
     1981 aatattattc aatttactta tagtatcttc aatgtcttcg taatttattt ctaatactaa
     2041 atattctgca tctaatgtta agacctcttt aatcccctct tcagataaaa ttcctcttcc
     2101 tataccaaca tgtgtatcat tgataccatc attatcactt aagtgtatca gtcttatttt
     2161 atcctttaag ttctttacat aagcatcctc atcaattaaa cagtgtccag tatcgtaaca
     2221 aaaacaaatc ttagaatttt taatcctctt aaatatatat tcaaaatcat aagatatatt
     2281 tccaatattt gaaaaatccc caccttttga ataagtattc tctatacata catatgaatt
     2341 tgtatttaat ttatctaaaa aatccacact atttcctaaa tatttgtctc tattctttct
     2401 aactctattt gtcataacat atcccaaatg aaggttaaaa taccttaaat caaatccttt
     2461 tagttcaaat tctatcttct caataaaatt tatccatgaa tttcgtatat actctatgtt
     2521 ttcgcaagta tttaattcca taggcaagtg tatccctata gataatccta acttagaaat
     2581 tctctcttta tatttacata actcactaca ttcagatata ttgtcaattc caatctctaa
     2641 atgagttatt tgctttatac tctcacaaat gtttaaagcc tcctcaatat taaacaataa
     2701 ggacgctata ccaactgcca tacaaatcac ctactcaaaa atacctatat ctgtaaaagg
     2761 aaatactctt aaaataactt ttcctttaat attttcttca tctactaatc ccacttcttt
     2821 atatctactg tctaaactaa cttctctatt gtctcccatc gcaaatactt ttcccttagg
     2881 aatcaccata tcaatatcgc cttcagtata attatcatgt atatatgaaa cttcatttaa
     2941 taacttacca tttatataaa ccttagaatc cttaattttt agatggtcac caggaacacc
     3001 tataaccctt tttacaagct cttttttcct tccattctct tgtaataaat cagtcttaaa
     3061 tatcattata tctccacatt ttggttctga taacttatat gtcatcctgt ttgctaccaa
     3121 ataatcatgt gatttaagtg ttgggtacat tgattctcca tttactaatg ttggttttat
     3181 aaaacgagtt ataataaatg caaaaaaaag tgcagtaata attattttta tccactctac
     3241 aatctcttct ttaatagttt cattcattca caaattctcc tttatagtta tattatcttt
     3301 attgataatg tctcttaaac actatctttt agataagtct actaaataag gtgttgtctt
     3361 ttttatatag acaactattg tgtatggtct ggtgatttca gctaatcagc gattgctcca
     3421 aattttatat gtttagtcaa tagttcctat cttagaaaat ggatacaatc tgactagaac
     3481 ctttcctaaa atggtatgct cgtcgaccaa tccaacctca tcgtatctac tatctaaact
     3541 tttttctcta ttatctccca ttgcaaataa ttttccttct ggaactacga tatcaatatc
     3601 tccatcagta cgattattat gtatatagga agtctcatct aacaacttat catttacata
     3661 taccttggag tcttgtattt ttacatggtc accaggaacc ccgataactc tttttactaa
     3721 atcttttttc tttccatttt cctctgttaa gtcggttttg aatactatta tatctttgta
     3781 ttttggctct cctaccttgt acgcaattct gttaactatc aaataatcac gttcaactaa
     3841 tgtaggatac attgattctc ctttgactat tgttggcact ataaaacgag ttattgcaaa
     3901 tgccaaaaca agagctatga caatcacttt tatccattct acaacttctt ttttaactgc
     3961 ttcacccact aaaatcgtct cctctgtgtt aaatattaag tcaatctaca gcaaaataat
     4021 ctaccataaa cctacaatat aaatattata cttctttttt ctaatagttt aaaatacttt
     4081 tctaagacct ttaggataat gattcttaat tacaccagaa gattcttttc cccaacctaa
     4141 aggtattcct tcaaccgaaa ccaaaaccca tcctctacta tcattagaat ttacaacatc
     4201 cccttttaaa tatttaagaa ttgattcact ctgtacactg aagttttcaa cattttttac
     4261 atcttcaact tttaagtaat gagatagtgc atgagaaggc tcaaatctat tcttctttaa
     4321 aacccctaaa tgcaaaccat atctcaatac ttttagtttt ttcgtatctg gatatatttc
     4381 aggaagtagg tacaaatttt ctcctcttaa ataaaattta ttttttttat tactataaaa
     4441 atcaaccttt aaaaatttct tttcaaactc cctataatcc tttatttctt tatctaaatt
     4501 ttttattttt aattctttga cattacattc ttcttcttct aattttttta ttttggcaac
     4561 aaaatgacct tctcccttta tcttatgagg ccataatctt tccatttcaa taagttctgc
     4621 atgtggatat tcactgataa actcatttat aacatgctca ttttcctccc ttgaaaaagt
     4681 acaagttgag taaattaaaa tgccatcctt ctttaacatt ttatatccat ctcttataat
     4741 ctctttttgg atggattgac attctactac ctttgcataa ctccaatctg atatggcaac
     4801 ctcatccttc ctaaacatac cttgcccaga acaaggtgca tctataataa ccttatcaaa
     4861 atacccatta aacgtctttc ttaagctatt agaatcggtg tttgttataa tacaatttct
     4921 cgctccaaat cgctctaaat tttcccctag agccttaatt ctactagcat taatttcatt
     4981 agaaaccaat aaacctgtat cgtttagctt agatagtata tatgtagatt ttccaccagg
     5041 agcagcacac atatcgagaa ctttttcacc ctctttaata tctgcctttg gtattacact
     5101 cattgcagaa ggctcttgca aatagtatgc tccagcctca tgcagtggat ttctaccagg
     5161 tctgtcaatt ttatcatcat aataaaaacc ttcttctgcc catggtattt gattcaaatc
     5221 aaacaactcc aaatcaaata attttttctt gtcaattttt aaagtattta ttctaagccc
     5281 agtagtctta ctttcctcat aactttttat aaaatcatca tattcatctt ttagtatttc
     5341 ttcaatatct tctaaaaatt cctttggtaa ttctgtcaaa tctataatcc cccttcaatc
     5401 tgctttactt gtgtgtcatt tattatactt taattattta tgtctttcct ttaaatttta
     5461 tttcttcttc tttttcctaa gattaccgaa aaacactttt ttagagtgat tcatatattt
     5521 ctcaagttta tcaagattta tcttccacaa aattattaca taaactataa gtaatataat
     5581 agcccatcta tattctatca tcaatatgaa atcaaaaact ccatgtaata aaattggaat
     5641 taacactgcc ataaacaaat actcacgtct tttattttta tttccctcaa atttatactt
     5701 agaaatatag tagcccatag taattgcaaa cattacatga gctggtatag agataactgc
     5761 cctattaata ccaacttgca gtgctagatt tctactttca gaaaaaatat aaaccatatt
     5821 ttcaattgtt gcaaatccta aagctaaaaa tacagagtaa ataataccat ctaacttttc
     5881 agtaaagtgt ttttctttaa ttagggcagg aatcagtatc agagctttta caccttcttc
     5941 tacaagtcct gcaactacaa atgatacata tattagttct gaataccctt caaatacatt
     6001 aaacttcatc agtaaatttt ctaaaagtat aattataaca cttagaaaag cacctattaa
     6061 aaaaaattta attagatgga ttaggggttc tctacaatat ctatctttag accttatcca
     6121 aaacatccct atcaatatag gaactattgc taataaaaat aaatctagct tcatagatta
     6181 ttttcctttc aaaatttttg atttatttat gatttatatc atctacttat ttttaactta
     6241 ttcgtgtttt aaatacatac taaaatatac attaaattat tttaaattat ttaaatacaa
     6301 atatactcaa atactcaaaa aaatttaaat ttatatctat attatttaac aaatttcaag
     6361 ctatattcat atcttgaaat ataagggaac taaattcatt taaagaaagg gtgatttgat
     6421 gcaagatggt ttcttaacag taagcataat tgatgctact aacaatagac ctattcaaaa
     6481 tgcagtagta aacatatatt caatgtctaa tggtagccaa agctcatcaa ctttatacca
     6541 aaacctaaga agtaatgaat ctggtcaagt gactggttta gtattaccag caccagatgt
     6601 agattactct ctacaaccat ctgatgttag accttatagc cagtatatag tggaagccat
     6661 agcagatgga tatgagacag ttgtcataga aggaacacag ttgttagcta caattgaagc
     6721 aagacaagga gttcccatgt ctcctagaac aagaagtaag cgttctttct caagacaaag
     6781 tgagttgatt tttgatatag gagaacatac tctatatggt acttatcctc ctaagattcc
     6841 agaaagtaac ttaaaaccat taccacctcc tactggtttc gttgtattag ataaccctgt
     6901 agtgcctgaa tttatagtag ttcatgatgg tttgccagaa gattcatcag ctccaaacta
     6961 ttggattcca tttaaagagt acattaaaaa catagcgtca tctgaaatat attcaacttg
     7021 gcctgaacag acaatctatg caaatgtaat agctataata tcatttactt taaatagagt
     7081 ctttactgaa tggtatagaa ataaaggata taactttaca ataacttcaa caacagcata
     7141 cgaccataag tttataaata atagaaactt atttgaacca attaacgtag ttgtagatgc
     7201 tatttttaat acttttataa aaagacctcc tacatcaaga cagccactat tagcacaata
     7261 ttgtgatgga caaaaatccc aatgtcctga ccaaatgact caatggggca gtaaagactt
     7321 aggtgaccaa ggatatgact atgagagtat actaagatat ttctatggag atgagatagt
     7381 atttgaaaga gcacctatag taagtggtgt accagtgtca ttccctggta ctacactaca
     7441 agttggttct tctgggcagt atgttagaac catacaaaat cagttaaatg ctatatctaa
     7501 ttcttatcca gctgtaccaa aagttataga agatggtatc tatggaacag atacagaaaa
     7561 cgctgttaag atattccaag gaatctttgg tttacctcaa agcggagtag tagattttaa
     7621 aacatggtat gaaatatcca gagtttatgt agctacaact agaatagctt ctttaaatcc
     7681 tttaatttaa agcttgattt agaacataaa ctcaaattat tgaataaaat tattaattta
     7741 aaataaaagt ggctgttatg aactaatata taccataagt attacttata agtattgtag
     7801 tcttaacagc cattttttag ttataacttg tttttttaga atcttaaaac tttaaatggg
     7861 ggattttaag cttcttaaaa acagtgctta gcaacttaga tttctttaaa atattatatt
     7921 tatttttaag tttaataaaa tgctattcta acgaaaaacc tactttttat ttaaaatctc
     7981 acttattatt taaaatgcta cttctcactt agagtattac tccttattat ttaaaacact
     8041 atctatcact tagagtatta cttcttatta tttaaaacac tatctatcac ttagaatatt
     8101 acttcttata taaattatta tttattataa atacaaataa tattaattta aaaagttatt
     8161 cctaatttaa ataatactat tatcttcatc agtgaatcta aactgcaact ttagacttat
     8221 tagctaaagc caatattaga cctaaagcta tagatgcaaa tgcagaagca attactctat
     8281 actcagcagg gaataagaat acaattgtat gacatggtat ccagaaaaat ggtatagttt
     8341 ttaaaacact aaaaccaagg taagcattcc agtccacaat atttaccaca tctttaagtt
     8401 ttaccttaat cccctttcca acctcatatt ttttatctat aaaacagtcc ataaccttat
     8461 ggaataaaaa tacagttggt gacattagta tattcatagt tgcactctta aatagagcat
     8521 ttgcaaaagc tattccctca aatggaagca taccatccac ttgtgcttga cctacacctg
     8581 atgagtagat tgacattcca tatgtggtaa ctacacctat tattccccaa actattgctc
     8641 tataaaatac tcctactggt attttccaat ccttatacaa aattctagca ccaagtaaat
     8701 ctcccattgt agctaataca gcaaacttta aaaaacctcc aatatatgga tgtgcacctg
     8761 ttgcttccat aaatacttct ctactacttg gtattgctaa gacagcaata atacaaataa
     8821 gaactccact ccatataaaa tcgccttttt tcatatttat aaatactatt taatatataa
     8881 atagttctcc tttctattaa agatttattt aatttacaat ctatctacaa ttatttatta
     8941 atcacttatt attagatatt cattttccat atttaaattt attctatccc tttatctatt
     9001 tattttctta ctactctatc caccattatc tatatattta ttttacgatt actctttcac
     9061 cctaaccctt taactatcta ttttttctta ctattcttat ccacatcatc catatattta
     9121 ttttacgatt actctttcac tctaaccctt taactatcta ttttttctga tattcttatc
     9181 caccatcatc catatattta ttttacgatt actctttcac cctaaccctt taactatcta
     9241 tttttttctg gtattcttat ctactattat ctgtatattt attttatgat tactctttta
     9301 acctaccccc tatactttat agtaatatgt ttttaacctt tttcattatt cccaatatgc
     9361 tttataacta caaatactct ccccccttaa aaataataat aaaattaatc aataaattta
     9421 taatcatatt attactctat gtattaagca attactatgc caataaactt tgattttttt
     9481 aaacaaatct taaaaatcct aaaatgctaa ttttctttaa cttttaatga atctaataga
     9541 taacatttaa ttttcgttat atttttcaga atatttctat tattattttt aagaaaaaaa
     9601 aataatgtta acatttctta acatacatta aaaaatgtta acattataaa ttgggtttaa
     9661 tacttttact ttgactcgat ttacttttat tctacttctt actttatttt taacttagac
     9721 tttatttttt tattacttat ttgagtctta tttattttat tctcactcca tatgttcaat
     9781 tacatttgtc taaattcttt gatactttta ttacataatt ttaacaagct taagtgttat
     9841 ttggatagtg cagttgataa ttatttaaat aatcatcaac tgcatgttta tatcattaca
     9901 gtagcttaat gtatttaatc atacttactt aggattttga aatatcttag agattatatt
     9961 taacattagt caattgctgc ataattgtaa gcaattgaaa tttgagaccc atcttcattt
    10021 tctatagtga taggcttcat aatttttaat ccttcagttt ttatcttttc taattcttgt
    10081 tccattttct taattgtttc ctcaaggtct ttttgactta catctttgac tgcattaggg
    10141 tctttagcat actcttttaa ttcttgaata tgtttagcat actcttcata agtataatgc
    10201 tcaacaccat acttttccaa ttcagtaggg tcagttattc ctgattttat tagagattca
    10261 aatttaggta aagcaatatt agatgaatca tttccatttg caaatactgc tccagttcct
    10321 cctagtacca ttgcagatac catcattgca cttataaggg atttttttat tttcataacc
    10381 aatcttcctt tcttagagat ttatttgggt agtgtagttt aaaatgacta ttgcaatagt
    10441 tatcaaccac atccttagac tatcacagta gtcatgttta tgtcaagcct ttttaaaaaa
    10501 cttttcaata aaaaatacta tctcaaaaca aaattaatta ttttgagata gtattttaat
    10561 tctaaatctt ttatattact aagatttatg gttactctat ccatgttcta tattgttctt
    10621 tattaactgc taacaaattc ccttttcttg atatgacaaa gcgattatca ttatagccac
    10681 ttcgctcaat tgaaacttct cctgaatcag tataaagtac atccttacta ttactagatt
    10741 tatttacata cgtttcttca ctattctctg aattagttac tttgctcata gatgattctt
    10801 catgctctct aaattcaatt acagatactt tcgccgtact aaaatgagtc tctccatcac
    10861 ttttagcttt actaacaaga atatcagatt ctactttggg agaatataaa tcagttgatt
    10921 tactacttat tgaaaatcca attttatcac tttgttcatt ttttgttaaa ccaaaagatt
    10981 caacctcatt aatctcttta ttttctgttg caaaaacaag acctgtccca caaactaata
    11041 cagttgaaac taaaaaagta acataagttg attttttaaa tttcataata ttaactattc
    11101 tcttttctat ttttgtcttt ccaaatccac tacatattgt cattgaaaat ggattattct
    11161 cctctgctag acttattagt gtggttgcat aatcagccct atattcttca ccaagtatac
    11221 tcataacctt ttcatcacaa ctaaattcta tgtctttatt tagtaaaaaa aacatcaccc
    11281 aaactaaggg attaaaccaa tggacaacaa gagctacaag cataaataac tttaacagat
    11341 tatcaaagct attaatatga accatttcat gagttaaaac aaagtctaaa gtttgattat
    11401 tagcataatt catttgcttt ggcaaaataa ttcgtggttt taaaatacca gatgtaagtg
    11461 gtgtcctagt aaattcagat atgcaaacaa taaatcttct aaaacggcta ttcttacaca
    11521 tccatttttt aatgaactca tgatttttta tatgaattga agttttaaaa agattaatta
    11581 ttttaaaata tctaaagcat aaaagtatgc taaacataat agtaactata aaagacaaaa
    11641 tgcccaacat ttccaacatc ataatatttt caatattaga cattatttca aattcgtcag
    11701 aattgttttt acctgtagag tcactagctt tcttaagagt ataattttct gttgatgtat
    11761 tacccaattc cacatcaaaa gtcgattcaa ttatactata aatactaaaa ccagaattta
    11821 aacttactgg tattagaagt ttaaataaaa caatcaacca caataataca aatacctttt
    11881 taggtaattt tttaaataaa catgctctta taaaaataac tattaaaagt aatactccag
    11941 aagtaaaact catttctaac aatttaatga acataaatct tacctcactt taatttttca
    12001 acaatttgtt taagttttgt aatctcatca cttgaaagat tttctttatt aataaaagct
    12061 gaaagaaatt tttctgaaga ccctccaaac attttattaa ttaaagtttc tgtttcctgt
    12121 ttttgtactt cctctttgct tattaaagct ttacaaacaa aattcggctc aattctctct
    12181 attgcacctt ttgacactaa tttttttata acggtatacg tagtgtttct attccatcct
    12241 gtttcttctt ttaaaatttt tactaactct ccagccttgc tttctcctct ctcccataga
    12301 acttccatta ctttaagttc tgaatcaaat aattttatct ccatataaaa tcgctcctca
    12361 aatatagtta tcacaatagt cattactata ataaaaaact atcatagtag tctatactat
    12421 gtcaatcatt tattttttaa taataaaaac tgtcttttta aaaaattctt ataaaagaca
    12481 gttttatcaa tgttatactt taatgtttaa ttaaagccat attttattta aatatataac
    12541 tatctatctt agtacatagt ataagatttt tctttatcta atagtatatc ctctacatct
    12601 gggttttctt ttactaattg tctataaaaa ttacaattag taacacctac atatggaatt
    12661 agccatagta gacctattcc aagagtagct attgaaagta tataccatcc tataaaacta
    12721 aagtttagta caaataattt aagtacattt cctttcatca tatctaaact agcacccatt
    12781 gatttaaata cacccatatt atccttgtct tcacaaatta agaaagtagc ttgagaaaca
    12841 tataatagca atatataaac cggtaacata agaacaagta ttataagaac tagagttatt
    12901 ccagtagaaa taatagtccc tattccaaca ttatcacttg ataaatattc aattgctcca
    12961 ctagtaagta aaactccaaa tgataaaaac gctcctataa ttgtgattat aaaagaataa
    13021 atataaacaa taattgattc aaataaataa aaaccaaaac ttcttaaata aattctccca
    13081 cttacaaaga tatctcctat cttgactttt tcatctttag taattttcaa gaacatacat
    13141 gtaaatcctg ctgaaacgca aaaagctatt acagccacta caatagtagt caatggttca
    13201 aaaggtaatc ctacaattga tattaatact atcaatgcaa tatatactgc catagaaatt
    13261 gcacatatcc cccagtttcc agataactga gctttagata ctcgttttaa ttcttgcctt
    13321 gataccataa aaacacccct ttcattttat aaaaaaactt ttaaaaatat aaataatctt
    13381 ttaacgtata atattaatat atcatatttt cgactatata agatacaatt attcaccatg
    13441 ttttatcaag atatgccata attgtattac tagttttata tagtcaacat taccaaatac
    13501 atcaaataaa tttgattaat tattcaacaa gtaataaaat aatttctatt aattatactt
    13561 tatttagtaa acaaattatt taataaaaaa attacttaat acagtaaatt aattggtaag
    13621 ataaattatt tattattagt aaagt
//
LOCUS       DAEORM030000082        13290 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.085, whole genome shotgun sequence.
ACCESSION   DAEORM030000082 DAEORM030000000
VERSION     DAEORM030000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 13290)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13290)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 13290)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13290
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.085"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            295..2112
                     /locus_tag="KRH23_003409"
     CDS             295..2112
                     /locus_tag="KRH23_003409"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0052621 - diguanylate cyclase activity
                     [Evidence IEA];
                     GO_function: GO:0071111 - cyclic-guanylate-specific
                     phosphodiesterase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="HHS5226680.1"
                     /translation="MLIFISFISIKLIHNVGDYGKLINYVGIVRGASQRLTKLEMNHQ
                     PNDELIEYIDEILQELITGHGDYGLVITDCNEYNEDLLLLEKKWEDLNIEIKKVRMKE
                     QDNQLLSISEEFFSLANDTVFKIENFSKEKSNYLMTLIIIISIIGILACIILILQYSK
                     KMVRLEKLNVDLKNIAYKDELTGVNTIEKFKLDANQNICIHKDKKFAVFYIDFENFKY
                     INDIFGYDYGDMILKRYANLMMNDIGKYEIFAREIADRFVALRCYVDKEDLVVRQRDV
                     DNELINITNEIKNKHSITVVSGICCIEDVNEKLSIDGLINRANFAQKTVKNKPGTNYA
                     FYNDSIRKKMIEENTIKSRIHEAIEKREFIVYLQPKVNLHSQKINCAEALVRWLTPDK
                     GIISPAIFIPVLEKNFFIALVDKYVFEEVCKWIRKRLDENKPFVQISVNVSRIQFYNT
                     KFVETYSNIQNKYRIPKNTIEIEFTESVAFENQKHLLEIIHDLHENGFTCSLDDFGKG
                     YSSLSVLKDLPFDVLKLDSMFFKASLDKDKEKIVIKNIVHMLKELNITTVAEGIECKE
                     QVEFLRDIGCDLVQGFVFYKPMPILEFEKILDKEFVYNS"
     gene            complement(2404..3003)
                     /locus_tag="KRH23_003410"
     CDS             complement(2404..3003)
                     /locus_tag="KRH23_003410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0046690 - response to tellurium ion
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HHS5226681.1"
                     /translation="MAIELKKGQKINLTKKENSDLGEILVNLNWNQKVQKKGFFGSLR
                     SSNIDLDLGCLFEMKNGVKGAVQALGNAFGSLDNPPFAQLDGDDRTGSNTQGENLRIN
                     GNKIKDIKRILIYAFIYEGVANWSEADGIVTIKQKQDSDLVVKLDEHKNGYNMCSIAL
                     IENVNDETFSVEKVVKYFKGHREMDTEFHWGLKWVAGRK"
     gene            complement(3106..3903)
                     /locus_tag="KRH23_003411"
     CDS             complement(3106..3903)
                     /locus_tag="KRH23_003411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HHS5226682.1"
                     /translation="MKFKKLLCLLLCLVLTLAVVGCSKAKDDKKIVVGATLVPGGELL
                     EELKPLIKEKGYTLEVKNFDDYILPNEALNNGEIDANLFQHEPYLKEAVKAKGYKIMA
                     GKKLYVCPAILYSYKIKSVDEFKKGDTIAISNNPSSCSKNLRYLESIGLLTLPKGDGL
                     VSPKDIIENPKGIQFKELDIAQIPSSLPDVTAAFIDTTYAVPAGLDAKKNGIYTAPIN
                     DEYANLLAFRTEDKDSEKIKVLQDVLTSDKARNLIEEKYKGIVIPTF"
     regulatory      complement(4016..4121)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            complement(4213..5199)
                     /locus_tag="KRH23_003412"
     CDS             complement(4213..5199)
                     /locus_tag="KRH23_003412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HHS5226683.1"
                     /translation="MLLIYNEKTNPYFNLAMEEYLLKNFDEDLFILWRNEPSIIVGKN
                     QNTLSEINLEYIKEYSIPVVRRQSGGGAVFHDLGNINFTFIACNNNNFSDFRRFTQPI
                     IDLLKTLDVNAEFSGRNDLLIDGKKFSGNAQYNYKNKVMHHGTLLFSSEINDLSKALK
                     VKPIKFEGKGIKSVKSRVTNISEHLHSKMDILEFKDAIMDYLSKTNIDNTNYCLSEHD
                     IKQIEKLTKSKYETWDWNFGNSPKYTLSNELKYSGGNVEFNLNVDKGIITSIKFFGDF
                     FGKCDVAFVENKLIGIRHEENALRNILDSIEINDYFLGADTDILVSGILGVK"
     regulatory      5363..5539
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00168"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Lysine riboswitch is most abundant in Firmicutes
                     and Gammaproteobacteria where they are found upstream of a
                     number of genes involved in lysine biosynthesis, transport
                     and catabolism; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="lysine"
                     /db_xref="RFAM:RF00168"
     gene            5683..7413
                     /locus_tag="KRH23_003413"
     CDS             5683..7413
                     /locus_tag="KRH23_003413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC family protein"
                     /protein_id="HHS5226684.1"
                     /translation="MRNKKINIIFLTTIMFIMSTVMVFAEEDIDTIALANAEKFGILT
                     LIPPLVAIILAFITKNVIISLLIGILSGSFIIKASGINVFATFIQAFLDLVDRALVSL
                     ADPWNAGIILQVLAIGGVINLVAKMGGAKAIAEALAKRAKSAKGTQLITWFLGLLVFF
                     DDYANSLIVGPMMRPVADKMKISREKLAFIIDATAAPVAGLAIISTWIGLEVGLIHDA
                     FESISIDVDAFGIFLNTIPFRFYNILILAFIVISALLLKEFGPMRKAEIKSRSRKISI
                     DLDEGVEELDDLAPKNGVKLSVWNAIIPIGTLIIVALASFYYSGYTSIMGGDDKALIQ
                     LFTNSPYSFEAIKEAFSASDASRALFQSALVASLVAIIMAVVKKIFTISEAIDVWIDG
                     MKSLVITGVILILAWSLSSVIKELGTAKFLIHLLSGSLPPFLLPSLIFGLGAIISFAT
                     GTAYGTMGILMPLAIPLAYSLNPDMSYVIVSTSAVLTGAIFGDHCSPISDTTILSSMG
                     AGCNHIDHVNTQMPYAIFTAVITIVFGYIPAGLGLPIYIVLPVAIAAIFVGIQIIGKK
                     VDEAEIELVE"
     gene            7523..7603
                     /locus_tag="KRH23_003414"
     tRNA            7523..7603
                     /locus_tag="KRH23_003414"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:7557..7559,aa:Leu,seq:tag)
     gene            7938..8453
                     /locus_tag="KRH23_003415"
     CDS             7938..8453
                     /locus_tag="KRH23_003415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HXXEE domain-containing protein"
                     /protein_id="HHS5226685.1"
                     /translation="MEKYIWLFPLLFIFHDMEEIIGFGIWLKKNKSMLDKKYPFISKV
                     YENYSTEGMAFAVFEEFILCIIFCILTVITENQYVYLLWLGSFIAYTLHLVIHIGQSI
                     IIRKYIPSLITSIICLPISIWCISKSIYIVDCEMSTTILYSIIGIIIVALNLKFAQSL
                     IGKFTKWMSNI"
     regulatory      8945..9049
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     regulatory      9053..9141
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            9259..11733
                     /gene="gcvPA"
                     /locus_tag="KRH23_003416"
     CDS             9259..11733
                     /gene="gcvPA"
                     /locus_tag="KRH23_003416"
                     /EC_number="1.4.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004375 - glycine dehydrogenase
                     (decarboxylating) activity [Evidence IEA];
                     GO_process: GO:0006546 - glycine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminomethyl-transferring glycine dehydrogenase
                     subunit GcvPA"
                     /protein_id="HHS5226686.1"
                     /translation="MNELKRVSLYNIHKELGAKLVEFAGWEMPLEYEGINKEHEKVRK
                     SAGIFDVSHMGEVQIKGAESEKFIQNLVTNDISALKINDIIYTPMCYENGGVVDDLLI
                     YKFGEEDYLLVINAGNIDKDVAWIIKQSEGYNVDIKNISSEVSQLAIQGPKAEEILQK
                     ITDIDLNSIKFYKSIPSTKVCGCPCLVSRTGYTGEDGFEIYCKNKYVEIIWNEVLKVG
                     GEDICPAGLGCRDTLRFEAALPLYGHEINEHISPIEGGLSIFVKTNKESFIGKSILSK
                     EKESGAKRKLVGFEMQGKGMPRNGYDIRIGDKTVGFVTTGCASPTTGKILGMGIIDSE
                     YAKVGNEIGIAIRKKVVPAVIVKKPFYKKQYKKDNIILNKENKFSYIPATSEDKSKML
                     KVVGLNSVDELFSDIPEEVKLKRDLNLEIGKSELEVSKIVKRLSEENLSLEDLTCFLG
                     AGAYDHYIPSIIKHITSRSEFYTAYTPYQAEISQGTLQVVFEFQSMIAEITGMEIANA
                     SMYDGATAAIEACIMAMNQTRKSKIVVSKTIHPETLSVLRTYLQYKDCEIVEIDFCNE
                     YGTTDIEKLKASVDKDTACVLIQTPNFFGIIEEMKEIEKITHENKAMLIMSVDPISLG
                     VLKTPGEIGADIVVGEAQSLGNPLNFGGPYVGFLASKSKYTRKMPGRIVGQSLDVEGK
                     IAYVLTLQTREQHVRREKATSNICSNQALNALVASIYMATMGKEGFKEVGMQSMKKAH
                     YTYNKLVQTGKYKPIFKGKFFKEFAVQGNLNIETINDKLLEENILGGYNLEYNYPELK
                     NSTLLCVTEKRSKEEIDKLVGIMEGL"
     gene            11733..13190
                     /gene="gcvPB"
                     /locus_tag="KRH23_003417"
     CDS             11733..13190
                     /gene="gcvPB"
                     /locus_tag="KRH23_003417"
                     /EC_number="1.4.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004375 - glycine dehydrogenase
                     (decarboxylating) activity [Evidence IEA];
                     GO_process: GO:0006546 - glycine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminomethyl-transferring glycine dehydrogenase
                     subunit GcvPB"
                     /protein_id="HHS5226687.1"
                     /translation="MKEYNSLLIDISKKGRKAYSLPKLDIDDIKIEDMIDQDMARQSE
                     LNLPEVGELELVRHYTLLSNKNFGVDTGFYPLGSCTMKYNPKINEDMAALPNFTGMHP
                     YQSSDTAQGSLSLMYDLSRRLAEITGMDEVTLQPSAGSHGEFTGLMIIKAYHENRGDH
                     KRTKVIIPDSAHGTNPASAAMANFDVIQIASDKNGAVDINALKEILNDEVAALMLTNP
                     STLGLFEKNIKEIATLVHEAGGLLYYDGANMNAIMGVTRPGDMGFDVVHLNLHKTFST
                     PHGGGGPGAGPVGVKKELVPFLPIPVIERKEDKYVLNYDREKSIGKIKNFYGNFGVLV
                     RAYTYILTMGRDGLKEASEMAVLNANYIKESIKDDYILPIDTLCKHEFVLGGLPRGEA
                     NIKTIDIAKRLLDYGYHPPTMYFPLIINEALMIEPTESESIETLDSFIEAMKSVAKEA
                     KEEPELLKTAPHNTLVKRVDDARAVKKPILTWSQR"
BASE COUNT         4989 a         1574 c         2197 g         4530 t
ORIGIN      
        1 tgatataatt ttaataagtg gtttgtaatt aaaaagttta taaattacat taagagtaat
       61 aatctataag aacttatata ttagaaaaaa ttttgtatat atagaggact ctaaagatga
      121 actatgtaaa ataaggttta tatattctaa ttgtatagaa aattttattg ggaacgcatg
      181 tatagtatta gaaaaaatag tttgaaggta ttcaataaac ataaaaaaca atatagggga
      241 taaaggtgtt ttatgaagag atttttgagg agaattatct tagttttatt tattttgttg
      301 atttttataa gttttatttc tattaaatta attcataatg ttggagatta tggaaaattg
      361 attaattatg ttgggattgt tcgtggagct agtcaacgtc taactaaact agagatgaat
      421 catcaaccaa atgatgaatt aatagaatat attgatgaaa tcttacagga gttgattaca
      481 gggcatggag attatggttt agtaatcact gattgtaatg aatacaatga ggacttactt
      541 ttattagaaa aaaagtggga agatttaaat attgaaatta aaaaggtaag aatgaaagaa
      601 caggataacc agttattaag tataagtgaa gagttttttt ctcttgcaaa tgatacagtg
      661 tttaaaatag aaaacttttc taaagaaaaa agtaattact taatgacttt aataataatt
      721 atatctatta taggtatatt agcatgtatc atattgattt tacaatatag taaaaaaatg
      781 gttagactgg aaaaattaaa tgtagattta aaaaatattg catataaaga tgaactaaca
      841 ggagtaaata ctatagaaaa atttaaattg gatgcaaatc aaaatatttg tatacataag
      901 gataagaaat ttgctgtatt ctatattgat tttgaaaact ttaaatacat taatgatata
      961 tttggatatg attatggtga catgatactg aaaagatatg ctaatcttat gatgaatgac
     1021 atagggaaat atgaaatatt tgcaagagaa attgcagata gatttgttgc gttaagatgc
     1081 tatgtagata aggaagattt agtggtaaga caacgagatg tagacaatga actaattaat
     1141 ataacaaatg aaattaaaaa taaacatagt attactgttg ttagtggaat ttgttgtatt
     1201 gaagatgtaa atgaaaaatt aagtatagat ggtttaataa atagagcaaa ttttgcacaa
     1261 aaaactgtta agaataaacc aggtactaat tatgcttttt ataatgacag tattcgtaaa
     1321 aaaatgattg aagaaaatac tatcaagagt agaatacatg aagctattga aaaaagagaa
     1381 tttatagttt atttacagcc taaagttaat ttacatagtc aaaaaataaa ttgtgcagaa
     1441 gctttagttc gttggcttac tccggataaa ggtattatat ctccagcaat atttattcca
     1501 gtacttgaga agaatttttt tattgcctta gtagataagt atgtttttga ggaggtttgt
     1561 aaatggatta gaaagaggtt agatgaaaat aaaccttttg ttcagatatc agttaatgtt
     1621 tcaagaatac aattttataa cactaaattt gtagaaactt attccaatat acaaaataaa
     1681 tacaggatac ctaaaaatac tatagaaatt gaatttacag agagtgttgc ttttgagaat
     1741 caaaaacatc ttttggaaat tatacatgat ttgcatgaaa atggatttac ttgttcttta
     1801 gatgattttg gaaaaggtta ttcatcttta agtgttttaa aagatttacc atttgatgtt
     1861 ttaaagcttg actctatgtt tttcaaggct agtttagata aagataaaga gaaaatagta
     1921 ataaaaaata ttgtacatat gttaaaagaa cttaatatca caactgttgc tgagggcatt
     1981 gaatgcaagg aacaagttga atttcttagg gatattgggt gtgatttagt tcagggattt
     2041 gtattttata aaccaatgcc aatattagaa tttgaaaaaa tattggataa agagtttgtt
     2101 tataatagct aaaatgtact ttataaaata tgaactaatt aagtaaaatt attttgtact
     2161 gaataaattt ttactttatt tacagaataa tgattattta cagaaaagcg cgaaaagtgt
     2221 attcctttaa gtgtgggatg gatagcacaa ataggggata aaaaatattg gccacataag
     2281 aatgcataat aatataaata tttgaaaggt cagcattata taaaaattaa aaagaaaata
     2341 aataattttt ctataaaaaa gagactatga gaaaatttac tcatagtctc ctaaataatg
     2401 tatttatttt cttcctgcaa cccattttaa tccccaatga aattcagtat ccatttctct
     2461 atgacctttg aagtatttaa ctactttttc aacactgaat gtctcatcat ttacattttc
     2521 tatcaatgct attgaacaca tattatagcc atttttatgt tcatcaagtt tgacaactaa
     2581 gtctgaatct tgtttttgtt tgattgttac aattccatca gcttcagacc agttagctac
     2641 accttcgtat ataaaagcat aaataagtat tctttttata tcttttattt tattaccatt
     2701 tattcttaaa ttttctcctt gtgtattact tcctgttctg tcatctccat ctaattgagc
     2761 aaaaggtgga ttgtctaaac taccaaaggc atttcctaat gcttgaacag caccttttac
     2821 accatttttc atctcaaata ggcaacccaa atctaaatct atattactgc ttcttaaaga
     2881 gccaaagaaa cccttttttt gtactttttg attccaattt aaattaacta agatttcacc
     2941 taaatcgcta ttttcctttt ttgtaaggtt tattttttgt ccctttttta attctatagc
     3001 catagtaatc ttcctccaca aacatagatt tatttaaatg gtagcactta ataagtcaat
     3061 attcaacaag attagaataa taatattaaa attatactaa atatactaaa aagtaggaat
     3121 cacaatacct ttgtattttt cttcaattaa gtttcttgct ttatctgatg taagaacatc
     3181 ttgtagaact ttaatctttt cactgtcttt atcttcagtt ctaaatgcta aaagatttgc
     3241 atactcgtca tttataggag ctgtataaat tccgtttttc ttggcatcaa gaccagcagg
     3301 tacagcataa gtagtatcta taaatgcagc agtcacatct ggaagagaag atggaatttg
     3361 agcaatatct aactctttga attgtattcc ctttggattt tctattatgt ccttaggact
     3421 aactaatcca tcccctttag gtaacgttaa aagtccaata ctttcaaggt atctaaggtt
     3481 cttagaacaa gaagatgggt tattgcttat tgcaattgta tctccttttt taaattcatc
     3541 aacagatttt atcttataag agtaaagtat tgctgggcat acatatagtt ttttaccagc
     3601 cattattttg taacctttag ccttaacagc ttcttttaga taaggttcat gttgaaatag
     3661 atttgcatca atttcaccat tatttaaagc ttcgtttgga agtatgtaat catcaaagtt
     3721 tttaacttct aaagtatatc ctttttcttt aatgagtggt tttaattctt ctaataactc
     3781 tcctcccgga actaaagtag caccaacaac aattttttta tcatctttag ctttagaaca
     3841 tccaaccaca gctaaagtta atactagaca taataacaaa cataataatt ttttgaattt
     3901 catataaatt ccctcctgaa tataattgat tagttaaaaa taaaatacca ttctttatca
     3961 cactgcaaaa taaaaataag cctgagttta aactcaggct ttaaaagcta atttagactc
     4021 atctttcagt ataatactgc aggatttagc accaatgtat ataaaaatat actggttgct
     4081 gggtttcata gggccagtcc cttcaccact ctggataaga agtatcaatt tttaattatg
     4141 ttataaatat tatcatgatt ttttacgtct gtaaacataa ttttataaat attttaaaat
     4201 ctttaatgta ttttatttaa cacctaaaat tccagaaact agaatatcag tatcagcacc
     4261 taagaaatag tcatttattt caatagaatc cagaatattt ctcaaagcat tttcttcatg
     4321 ccttatacca ataagtttat tttctacaaa tgcaacatca cattttccaa aaaaatctcc
     4381 aaaaaatttt atactagtta ttatgccttt atcaacattt aaattaaact caacatttcc
     4441 accagaatat tttaattcat ttgaaagagt atattttggt gaattaccaa aattccaatc
     4501 ccaagtttcg tattttgatt tagtaagctt ttctatttgt tttatatcat gctcactcaa
     4561 acaataatta gtattatcaa tatttgtttt agaaagataa tccattatag catctttaaa
     4621 ttctaatatg tccatttttg aatgtaaatg ttcacttata ttggttacac gagattttac
     4681 agattttatt ccttttcctt caaattttat aggtttaacc tttaatgctt ttgagaggtc
     4741 atttatttca gatgaaaata aaagagtccc atgatgcatt actttgtttt tgtagttgta
     4801 ttgagcattt ccagaaaatt tcttgccatc tataagaagg tcatttcttc cagaaaattc
     4861 ggcattgaca tctagtgttt taagtaaatc tattatgggc tgagtgaatc ttctgaaatc
     4921 actaaaatta ttattgttac aagctataaa tgtaaaattt atatttccca aatcatgaaa
     4981 tacagctcca ccaccagact gtctcctaac gacaggtata gaatattctt ttatatattc
     5041 taaatttatt tcagaaagtg tgttttggtt ttttccaaca attatagaag gttcattcct
     5101 ccataaaata aataagtctt catcaaaatt ttttagaaga tattcttcca ttgctaaatt
     5161 aaaataaggg tttgtttttt cattataaat taataacatt aaagtagttc ctccatagaa
     5221 ttgataaaat ttttattatg aatacaatta attttataat tcgacaataa tataaaaact
     5281 cctttaaatt agaaatttta aaaaccacct tgcaaagttt aaataaataa tatatactca
     5341 aaatatgttt aataaaagtg aatagaaggg tagaggcgca ataatctatc agtactaata
     5401 aggagttaag cacagagagt tattaggaaa ggagatattg ccgaagtttt ataatcgatg
     5461 ctttaagatt atattgctgg gggtacatag aaaatatgta caactgtcac aggtttattt
     5521 gtggtgagct atcatttaag gaattatatt atatttattt ttactattgt tgatatattg
     5581 taatgtttaa gccttgagtg tttaccactc aaggcttttt tagttttatt gtaacataat
     5641 accctgtaca gttcacaaaa ttaaaaggag agggagattt atatgaggaa caaaaaaatt
     5701 aatattattt ttctgacgac aatcatgttc ataatgtcaa cagtaatggt ttttgcagaa
     5761 gaagatatag acactattgc actagccaat gcagaaaaat ttgggatttt aactttaata
     5821 ccaccattag ttgctataat actcgcattt ataactaaaa acgtaataat ttctttactt
     5881 ataggtattc tttctggtag ttttataatt aaagctagtg gtattaatgt ttttgcgaca
     5941 tttatacagg catttttaga tttagtagat agagctttag tatctttagc agacccttgg
     6001 aatgcgggga taatactaca ggttttggca attggaggag taataaatct tgttgctaaa
     6061 atgggaggag ctaaagctat agctgaagca cttgctaaaa gagcaaagtc agcaaaaggg
     6121 acacagctta taacatggtt tttggggctt ttagtattct ttgatgatta tgccaattca
     6181 ctaatagtag gtcctatgat gagacctgtt gcagataaaa tgaaaatatc gagagaaaag
     6241 ctagcattta taatagatgc cacagcagca ccagttgctg gtttagctat aatatctaca
     6301 tggataggtc ttgaggttgg tttaatacat gatgcttttg aaagtataag tatagatgta
     6361 gatgcatttg gtatattttt aaatacaata ccatttagat tttacaatat attaatatta
     6421 gctttcattg taatatcagc attattatta aaagaatttg gtccaatgag aaaagctgag
     6481 ataaaatcta gaagtagaaa aattagtata gaccttgatg aaggcgtaga agagttggac
     6541 gatttagctc caaaaaatgg agtaaaattg agtgtatgga atgctataat cccaatagga
     6601 acattgataa tagttgcatt agcatcattt tattatagtg gatatacatc tataatggga
     6661 ggagacgata aggctctgat acaactattt acaaattctc catattcttt tgaagcaata
     6721 aaagaagcat ttagtgcatc tgatgcatct agagcattat tccagtctgc acttgttgca
     6781 agtttagttg ctattataat ggctgtagta aaaaagattt ttacaatatc agaagcaatt
     6841 gatgtttgga tagatggaat gaaaagttta gtaatcactg gtgtaatatt aatacttgca
     6901 tggtcattaa gttcagtaat aaaagagtta ggtacagcta aatttttaat acacctatta
     6961 tcaggttcac taccaccatt cttattacca agtttaatat ttggtttagg agcaataata
     7021 tcttttgcta ctggaacagc ttatggaaca atgggtatac ttatgccact tgcaattcca
     7081 ttagcatact cattaaatcc tgatatgtct tatgtaatag taagtactag tgcagtttta
     7141 acaggtgcaa tatttggaga ccattgttct ccaatttcag atacaacaat actttcttca
     7201 atgggagctg gctgtaatca tatagaccat gttaacactc aaatgccata tgctatattt
     7261 acagcagtaa tcactattgt atttgggtat ataccagctg gacttggatt gccaatatat
     7321 atagtattac cagtggcaat agctgctata tttgtaggta ttcaaataat tggtaagaaa
     7381 gttgatgaag cggaaataga acttgtagaa taaagatata aataagtttc accttttatt
     7441 atcactattt tgttagtttt tagataattt taaaaagtta ttgaaaataa tggcgaaata
     7501 tagtaaaata aaagagtgat aagcggatgt ggcggaattg gcagacgcac tagacttagg
     7561 atctagcgcc attggcgtgg gggttcgact cccttcatcc gcactttaca gtacttaatt
     7621 gtactgaaaa aaactggggt tgctggcttt cggagtgggc tatcccgttt ttattttttt
     7681 gtatatataa tagattggca ctttagtata aggtgctttt tttataggca aaaacagtac
     7741 atttatttct gttttattat cattcatcta ttagaatata ctttagttaa gaatgtgtta
     7801 ataagcagtg ttcacattct tgataaaatg tggaataata tgtattttta ctaagacgga
     7861 aatgaaataa ttaaaccatt aaataatatt ataagatgat gaataagtag ataaatcaaa
     7921 ttttgtagga ggatattatg gaaaaatata tatggttgtt tccattactt tttatttttc
     7981 atgatatgga agagataata ggttttggaa tatggcttaa aaaaaataaa tcaatgcttg
     8041 ataagaagta tccatttatc agtaaagttt atgaaaatta tagtactgaa ggcatggcat
     8101 ttgctgtgtt tgaagaattt attttatgca ttattttctg tatacttaca gttataacag
     8161 agaatcagta tgtatatcta ctatggttag gtagttttat agcatatact ttacatttgg
     8221 taattcatat agggcagtca atcataataa gaaaatatat accttcactt attaccagta
     8281 tcatatgctt accaataagc atttggtgta taagtaagag tatttatata gttgattgtg
     8341 aaatgagtac aacaattctg tacagtataa ttggcattat aattgtagca ttgaatttaa
     8401 agtttgcaca gtcgctgatt ggaaaattta caaagtggat gtcaaacata taaattttag
     8461 tttattgtac agttcaagga atcagaaatt ggaattttat agtattaata ttttatagta
     8521 ttaatataat gtataaaatt ttatagcaat gtatttcata agtataaagt gactagaatt
     8581 ttaagaaata tacaaattct ataaaaacta aataatttca agtatatttt aaaaatctta
     8641 tttttcacaa gtttaaaatt gtaaacgatt tcatcaagtc tatgaatata cttttaacat
     8701 gttatagtaa atctcaatat aaatttacat ttggttcttt gtgtgttatt ttaataataa
     8761 attaagtgaa aatgttattt tacattaata tataatatct ttgcataaga gtgaataata
     8821 taaaagagaa ataattgata ataaaaactt aacaaaaaaa ttaatacata aaaaaaaata
     8881 aatataatgt gttgacattt aattgaaata ttcatacaat aaaattgaaa ataaatattt
     8941 ccaaatgaga ttagcgagag agtcctttat acgaaaaggc gccgaagaag aaatttaaga
     9001 aatgccaatt tttagagaag ctttcaggca aaaatatcgc taattgatgg gactctggag
     9061 agacttaagt taagatacta taagtcaccg aagaagcaaa ataatattaa attattaaat
     9121 ctttcaggta tacaaacagg gatatatagg ctaggattat tttccatgct gatatatctt
     9181 ttttttatga aaaagtacag gaaataatat caaagttact taaatacagt aggtctaatt
     9241 ttctagggag ggttatatat gaatgaattg aaaagagtat ctttgtacaa tatacacaaa
     9301 gagcttggag caaaacttgt tgaatttgct ggttgggaaa tgcctttaga atatgagggt
     9361 ataaataaag agcatgagaa ggtaagaaaa agtgcaggta tatttgatgt atctcatatg
     9421 ggagaggtac agataaaggg agcagagtca gaaaaattta tacaaaacct agttacaaat
     9481 gatataagcg cattaaagat aaatgacatt atatatacac ctatgtgtta tgaaaatggt
     9541 ggagtagttg atgatttatt aatatataaa tttggtgaag aagattattt attagtaata
     9601 aatgcaggta atatagataa agatgtagca tggataataa aacaaagtga aggatacaat
     9661 gtagatataa aaaatatatc tagtgaagtg agtcaattag caattcaagg acctaaagca
     9721 gaagaaattc ttcaaaaaat cacagatata gacttaaact caataaaatt ttataagtca
     9781 attccatcaa caaaagtatg tggttgtcct tgtttagttt caagaacagg atatactggg
     9841 gaagatgggt ttgagatata ctgtaaaaat aaatatgtag aaataatttg gaatgaagtt
     9901 ctaaaggttg gaggagaaga tatatgtcca gctggtttag gttgtaggga tactttgaga
     9961 tttgaagcag ctctacctct atatggacat gaaataaatg aacacatatc tccaattgaa
    10021 ggtggtttat ctatctttgt gaaaacaaat aaagaatcat ttattggcaa atcaatttta
    10081 tcaaaagaaa aagaaagtgg agctaaaaga aagttagtag gatttgaaat gcaaggtaaa
    10141 ggaatgccta gaaatggata tgatataagg attggtgata aaacagttgg atttgtaaca
    10201 acaggatgtg catctccaac gacaggaaaa attttaggta tgggaattat agattctgaa
    10261 tatgcaaaag taggaaatga aataggtata gcaatcagaa aaaaagttgt tcctgctgtg
    10321 atagttaaga aaccttttta taaaaaacaa tataaaaaag ataatattat attaaacaaa
    10381 gaaaataaat tttcatatat acctgctaca agtgaagata aatcaaaaat gttaaaagta
    10441 gttggattaa attcggttga tgaattattt tcagatatac cagaagaagt aaaattaaaa
    10501 agagatttaa atttggaaat tggaaaatct gaattagagg taagcaaaat agtaaaaaga
    10561 ttgtcagaag aaaatttaag tttagaagac ttgacttgtt ttcttggtgc tggtgcatat
    10621 gaccattata taccatcaat tataaaacat ataacttcaa gatctgaatt ttatacagca
    10681 tatactccat atcaagctga aataagtcag ggaactttac aagtagtttt tgaatttcaa
    10741 tctatgattg cagaaattac aggtatggaa attgcaaatg catcaatgta tgatggagca
    10801 actgctgcaa tagaagcatg tataatggca atgaatcaga ctagaaaaag taaaatagta
    10861 gtgtcaaaaa ctattcatcc tgaaactttg tcagtattaa gaacttactt acaatataaa
    10921 gattgtgaga tagtagaaat tgacttttgt aatgaatatg ggactacaga tatagaaaaa
    10981 ttaaaagctt ctgtagacaa agatacagca tgtgttctta tacaaactcc taatttcttt
    11041 ggaattattg aagaaatgaa agaaatagaa aagataactc atgaaaataa ggctatgtta
    11101 attatgagtg tagacccaat atcattagga gttttaaaaa caccaggtga gataggtgca
    11161 gatattgttg ttggagaagc tcaatcactt ggaaaccctc ttaattttgg aggtccttat
    11221 gtaggatttt tagctagcaa atctaaatat actagaaaaa tgccaggaag aatagttggg
    11281 caaagtttag atgtagaagg taaaattgca tatgtattaa ctttacaaac tagagaacag
    11341 catgtaagaa gagaaaaagc aacttctaat atatgttcaa atcaagcttt aaatgctctt
    11401 gtagcttcaa tatatatggc tactatgggt aaagaaggat ttaaagaggt tggtatgcag
    11461 tctatgaaaa aagcacatta tacttacaat aagcttgtac aaactggaaa atataagcca
    11521 atatttaaag gtaagttttt caaagaattt gctgtacaag gaaatcttaa tatagaaact
    11581 ataaatgata aactcttaga agaaaatata ttaggtggtt ataatttaga atacaattat
    11641 ccagaattaa aaaattcaac tttgctttgt gtgactgaga aaagaagcaa agaggaaata
    11701 gataagttag ttggaataat ggagggatta taatgaaaga atacaatagt ttgttgatag
    11761 atatatctaa aaaaggtagg aaagcatact cacttccaaa gttagatata gatgatataa
    11821 aaatagaaga tatgattgac caagatatgg caagacaaag tgagttgaat ttgccagaag
    11881 ttggtgaatt agaattagtt agacattata cattattatc aaataaaaac tttggagttg
    11941 atacaggttt ttatcctttg ggttcttgta ctatgaaata taatcctaaa ataaatgaag
    12001 atatggcagc acttccaaac tttactggaa tgcatccata ccaatcttcg gatacagctc
    12061 aaggctctct ttctttgatg tatgatttat caagaagact tgcagaaatt acaggtatgg
    12121 atgaagttac actacaacct tcagcaggtt ctcatggtga gtttacaggg cttatgatta
    12181 taaaagcata tcatgaaaat agaggtgacc ataagagaac caaagtgata attccagatt
    12241 ctgcacatgg aacaaatcca gcaagtgcag ctatggcaaa ctttgatgtg attcaaatag
    12301 catctgataa aaatggagct gtagacataa atgcattaaa agagattttg aatgatgaag
    12361 tagcagctct tatgcttact aatccaagta ctcttggttt atttgaaaaa aatataaaag
    12421 aaatagctac tcttgtacat gaagcaggag gacttttgta ctatgatggt gcaaacatga
    12481 acgctattat gggggtaaca agacctggag atatggggtt tgatgtggtt catcttaatc
    12541 ttcataagac tttttcaact cctcatggag gtggaggtcc aggagctggt cctgttggag
    12601 ttaaaaaaga attagtacct tttttaccaa taccagtaat tgaaagaaaa gaagataagt
    12661 atgtactaaa ttatgataga gaaaaatcta ttgggaaaat taaaaatttc tatggtaatt
    12721 ttggagttct tgtaagagct tacacatata tactaactat gggaagggat ggacttaaag
    12781 aggctagtga aatggcagtt ttaaatgcta attatataaa ggaaagtata aaagatgatt
    12841 atattttgcc aatagatacc ttgtgtaagc atgagtttgt attaggtgga ttgccaagag
    12901 gagaggccaa tataaaaact atcgatattg caaaaagact actagattat ggataccatc
    12961 ctccaacaat gtactttcct cttattataa atgaggcact tatgatagaa cctacagaaa
    13021 gtgagagtat agagacatta gatagtttta tagaagctat gaaaagtgtt gctaaagagg
    13081 caaaggaaga accagaacta ttgaaaactg ctccacataa tactttggtc aaaagagtag
    13141 atgatgcaag ggcagtaaag aaacctatac taacatggtc acaaagataa atagttaaaa
    13201 agtagagatt taaagtataa agagaattaa atttgtaaga aaaagctatc taacttaata
    13261 tagtttagat agcttttttg tatattagta
//
LOCUS       DAEORM030000083        13123 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.086, whole genome shotgun sequence.
ACCESSION   DAEORM030000083 DAEORM030000000
VERSION     DAEORM030000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 13123)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13123)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 13123)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13123
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.086"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            <1..200
                     /locus_tag="KRH23_003418"
     CDS             <1..200
                     /locus_tag="KRH23_003418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ORF6N domain-containing protein"
                     /protein_id="HHS5226688.1"
                     /translation="FGVDLHRRLINKRRKMAEEGVSESKREKVNNLDVIQDDKKLIEG
                     YVAIVKDMALKYGISSDLSKN"
     gene            complement(283..477)
                     /locus_tag="KRH23_003419"
     CDS             complement(283..477)
                     /locus_tag="KRH23_003419"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226689.1"
                     /translation="MKFVYVKIFNNWIDITDIGSINGCNAIEYINENLDKMYSSNYVS
                     INYKDKNYCIHPSCIQIVTK"
     gene            complement(633..851)
                     /locus_tag="KRH23_003420"
     CDS             complement(633..851)
                     /locus_tag="KRH23_003420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHS5226690.1"
                     /translation="MTKFKDNIKLVRKQMNMTQKQFASLFGISERAYQYYEAGSREPN
                     LETLILISNKLNVSTDFLLGLSPNQNRN"
     gene            943..1158
                     /locus_tag="KRH23_003421"
     CDS             943..1158
                     /locus_tag="KRH23_003421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HHS5226691.1"
                     /translation="MLNKKERVKINNNLKLQREKIGLTQLEVAQKAKITERSYQYYEA
                     GERLPNIRTALKIAIILNTNCEKLFNE"
     gene            1200..1994
                     /locus_tag="KRH23_003422"
     CDS             1200..1994
                     /locus_tag="KRH23_003422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor KilAC domain-containing
                     protein"
                     /protein_id="HHS5226692.1"
                     /translation="MNNLQLNNKNTITTLEIADMLEIRHWEVLRKLEGTEKTKGIIDI
                     LNDNNFVVVDYFIKSTYLDSKNESRPCYNVTKLGCDFLANKFTGEKGIIFTARYVRRF
                     NEMERVLKEQQPKLPTTYKEALQQLLVEVEEKEQLQLENQEKDKVIQLQQPKVLFADA
                     VSASNNSILVGELAKLIKQNGVDIGQNRLFTWMRENGYLIKCKGEDYNIPTQKSMNLR
                     IMEVKKRVINNPDGSTKVTRTVKITGKGQVYFVNKFKSSKQLSMLS"
     gene            2051..2260
                     /locus_tag="KRH23_003423"
     CDS             2051..2260
                     /locus_tag="KRH23_003423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226693.1"
                     /translation="MENKKIEEIEKRITMLENQLQAQLFSQITAQSNSDFIDYMYQCI
                     VLYLHEMNKSEKRKISEITKERIRK"
     gene            complement(2270..2644)
                     /locus_tag="KRH23_003424"
     CDS             complement(2270..2644)
                     /locus_tag="KRH23_003424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6173 family protein"
                     /protein_id="HHS5226694.1"
                     /translation="MQFSNNISKELQESIRKTVSDTSNTEYFYYAEFQYKIILKSIEE
                     FEKELDDEHEIALKLTNFGKDVLMIVEEVGYHNPCLIHYYGIVNGVYSEILQHTSQIN
                     FMITSVKKTDPSKPARRIGFIL"
     gene            2720..2917
                     /locus_tag="KRH23_003425"
     CDS             2720..2917
                     /locus_tag="KRH23_003425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHS5226695.1"
                     /translation="MLIGDNIKQILRKRDIKPYKLAKELNIDVSGLYKLLKNKNSNPT
                     IDTLIKLADYLDITLDELVGR"
     gene            2948..3340
                     /locus_tag="KRH23_003426"
     CDS             2948..3340
                     /locus_tag="KRH23_003426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHS5226696.1"
                     /translation="MDISESITKQFSDSLKSLIEIEINKQETDRVKSQTVEQKVKVLE
                     PKDIVVLIKRGYPNYLITVEEARGILKLDTVFMRRLVSTGLIKSLARGDGRKISRYEV
                     DDFIERNQGKNLDELLKAVERGDEIVKP"
     gene            3327..3470
                     /locus_tag="KRH23_003427"
     CDS             3327..3470
                     /locus_tag="KRH23_003427"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226697.1"
                     /translation="MLSLNTNKNNIVTLKKDGKVIADIVFKDIKTGKKISVGVLNKKV
                     LVK"
     gene            3637..3879
                     /locus_tag="KRH23_003428"
     CDS             3637..3879
                     /locus_tag="KRH23_003428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226698.1"
                     /translation="MEAARLIAIGQIKQAEKEICKLQGTKNNSSLMWWEAVKFASQNI
                     LEGLEHDIELEASIEFREAMMYQEELEKDRPIDVQI"
     gene            3958..4239
                     /locus_tag="KRH23_003429"
     CDS             3958..4239
                     /locus_tag="KRH23_003429"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226699.1"
                     /translation="MKTKNEIIKDLEDRLFLLRFTTVDEVDWDVKFGQISALEFCIDK
                     HRKGCTLQQFKENLEEYKLQGNYGDYIDGFVSVLERNIREMEGEIDGSE"
     gene            4226..4864
                     /locus_tag="KRH23_003430"
     CDS             4226..4864
                     /locus_tag="KRH23_003430"
                     /inference="COORDINATES: protein motif:HMM:NF016302.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ERF family protein"
                     /protein_id="HHS5226700.1"
                     /translation="MEVNNIYIKLMDVRIKFNKLDIKKSGQNKFANFKYFELADFLPQ
                     ATELLQEAKLCPIVTFTNDYATLTLINGEKPTEEIIFTSPMRELQLKGSNELQALGGI
                     ETYQTRYLYIQLLNITENDTFDATSGKEDYKRNDLTNSSIKASENGQIKISQNQIKRL
                     FSIGNTIGKDSDRVKSEVYYKFNKEVKDLSKQEYDQICVGYEKLQREKGIIK"
     gene            4874..5770
                     /locus_tag="KRH23_003431"
     CDS             4874..5770
                     /locus_tag="KRH23_003431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006269 - DNA replication, synthesis of
                     primer [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HHS5226701.1"
                     /translation="MKDRDKATIEKGNILSDGYGLSPQLVARDSWLTTGARALYFYLS
                     SFAGASGTCYPSRDIMTHELGINKDTFSKYLNELKTSGYIKVYKNKTREGRMQNNIYE
                     VVFDRSYIESHISIRCKKENKKKPCPKKADMEPCPNLPDMVQPDMEKSDTISNSIINN
                     SFKSSMYIEQAVDNSLKEFKKLYEENIGVVYPVTAEWLLEVSNEVDIRVFKRAIEICA
                     ERMNMNLSYLKGILKKWKDANITTYEQLESYKLQHENKKSKKTNSVVSKNKFANFEQT
                     FTQYSNKELDEIIKKSQKAKFK"
     gene            5790..6209
                     /locus_tag="KRH23_003432"
     CDS             5790..6209
                     /locus_tag="KRH23_003432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HHS5226702.1"
                     /translation="MNQVVLVGRLTRDPELKYIPGTGTAVASFTIAVDRNYINKEGKR
                     DTDFIPIEVIGKSAEYCANYITKGKLVALEGNIRVDNYKTQSGEKRTFIKVSTKSVQS
                     LESKSKSSNSYKESVQDGTIGLDPQGFEIIDDDELAF"
     gene            6238..6600
                     /locus_tag="KRH23_003433"
     CDS             6238..6600
                     /locus_tag="KRH23_003433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226703.1"
                     /translation="MFKVERYFSGSVVDNLIEDDLTCRNYLALYCCLLGITKNGKKIY
                     PKPEKMLAEFGVKKDRKIKKELPVRIRNVNTGEVKQFESIDGAACFLRLKYQAVYQAI
                     KKKSKTRSGWKAEYIEEE"
     gene            6600..6734
                     /locus_tag="KRH23_003434"
     CDS             6600..6734
                     /locus_tag="KRH23_003434"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226704.1"
                     /translation="MEVSRTEYTIKRAKELYDNGEDIFIAIDKAREKYEEMIKSEYLS
                     "
     gene            6834..7685
                     /locus_tag="KRH23_003435"
     CDS             6834..7685
                     /locus_tag="KRH23_003435"
                     /inference="COORDINATES: protein motif:HMM:NF012372.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HHS5226705.1"
                     /translation="MNVLSLFDGISCGQVAFERARIKVENYFASEIKEIAIKVAMNNY
                     PKTIQLGDVRELNVSKIPKVDILIGGSPCQNLSKGRLIANKIQDGLTGDKSNLFWEYI
                     RILKQLNPEYFLLENVVMPKKDENMISQLLGVEPIKINSNLVSYQNRDRLYWTNILNV
                     QQPKDLKISFQDYKDTSFDYCKEFEIKKTPSREKMWGNGLNGNCKNVTYEDKINCVTL
                     KQDRFSNSGLVEFGSFCRYLTTRELELAQTLPVGYTKGLSIRQAQNVIGDGWTIDVIA
                     HILSNIN"
     gene            8002..8199
                     /locus_tag="KRH23_003436"
     CDS             8002..8199
                     /locus_tag="KRH23_003436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226706.1"
                     /translation="MNKFQKAVSQMVKQEEKENLLQGYENCIVGRSISSSIRRYVKGF
                     KKFGYSVHEVYEFIDDINKYE"
     gene            8227..8643
                     /locus_tag="KRH23_003437"
     CDS             8227..8643
                     /locus_tag="KRH23_003437"
                     /inference="COORDINATES: protein motif:HMM:NF018101.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1064 domain-containing protein"
                     /protein_id="HHS5226707.1"
                     /translation="MSKYNNKKIVIDGIKFDSKDESEYYLYLKEKKENGEIKDFGLQQ
                     KFELQPKFKKDGKSYRAITYTVDFAIYKWNGEVVYIDVKGYSTQQGELRKKLFDYKYQ
                     DKKLIWIAKSKKYGVDGWIEYSELKKKRKENKKKVA"
     gene            8662..9162
                     /locus_tag="KRH23_003438"
     CDS             8662..9162
                     /locus_tag="KRH23_003438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226708.1"
                     /translation="MASKVKKEFFMATKKHLENYKQLHINIESLKLQIKNLKEFHLGD
                     FMQGLSYDSIPISKTNSISNQVENELINLEEKIIEKQIELYEMEALKYTIDVSISNLK
                     PIHKQIIRYRYIEGLEWSLIVDKVYLEERQLRERANQAISSISIALFGKKALIEQEPL
                     FKMLDL"
     gene            9584..9790
                     /locus_tag="KRH23_003439"
     CDS             9584..9790
                     /locus_tag="KRH23_003439"
                     /inference="COORDINATES: protein motif:HMM:NF040423.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHS5226709.1"
                     /translation="MNRFEGIYSFAEATKLWDLKDSTLRKAVATGKLVENIDCKKFGR
                     DWVVTIEAMEREYGKLNNIMKDLD"
     gene            10279..11466
                     /locus_tag="KRH23_003440"
     CDS             10279..11466
                     /locus_tag="KRH23_003440"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226710.1"
                     /translation="MLNEKNLKNIKNILQMVQMKHLKDFENWGINKRKKETAINSLIN
                     IIQNDGEKLDYFKEWISIFTIDGHNNYYVFNYNDSDLELEDLKNIVEDIVSENLLEID
                     TSDLEETKVIYKKNDVINKRLIIRFISPALISCKNENENGNIESGLEKTFYFATLFLD
                     LSLKQIIVSIPHTVGIKSIDNIEAKARDFSEIAKYYVSKLEDLLTTYNIQIEKYNDWI
                     YDATYELAEEGSAHNNPEINKKYEENIDKIDEFAKKIAIASGITDKAIIENFKEGVGI
                     LYENILIDEFGVVEDENQYSTFVQNGDGVNSYCRVGSKTATLKSGKGHAIAKTSRNNE
                     DVKNLGVMKSFNGTLSRFLIEVLDKELYLIRTDTSKFIEERVIYDVIRKVGEYKYTFR
                     KSE"
     gene            11411..11797
                     /locus_tag="KRH23_003441"
     CDS             11411..11797
                     /locus_tag="KRH23_003441"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226711.1"
                     /translation="MMLYEKLENISILLGNQSKAKSIIEELEKLMKSDIITPRLLARK
                     TKVTLLEATRVLEFLVKENELEFFIVVECSNPDSIYENEIGHYKYFTSIKEFNAFSKG
                     QECPICGCGYKYNFEDTKIGFRRLEK"
     gene            11802..12572
                     /locus_tag="KRH23_003442"
     CDS             11802..12572
                     /locus_tag="KRH23_003442"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: protein motif:HMM:NF016362.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA];
                     GO_process: GO:0009307 - DNA restriction-modification
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HHS5226712.1"
                     /translation="MSLDTLKEYLSICDDNLIWEPFYDDSMLLDEFSNYIKEIELSKE
                     WNKSKNHEKGKILEQLVRFIMSRFTILSDISVNKSTTDNELDVFVKFNDNIPIPFLCN
                     IKSKIVCECKNWKSRKVDVGMVSKLAEICNKNNAGLGIFISLNGLTGKGWQYAEGKRR
                     KLYLSDKMPIISFTVDEITKLKYKRYNLLTMIKCKMQALIDEMEFAGGELRLLESELG
                     FIDCLNENIESLKMLGLITEVEYNNIKVRINHRYDIVN"
     gene            12630..>13123
                     /gene="terS"
                     /locus_tag="KRH23_003443"
     CDS             12630..>13123
                     /gene="terS"
                     /locus_tag="KRH23_003443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit"
                     /protein_id="HHS5226713.1"
                     /translation="MQDVKEKVKQDYLKGMKQKEISAKYDISLNTLKSWIKRYNWANE
                     KKKGAPKNKRGAPIGNKNATGPPGNKNAEKFGFFSKYLPEETQDLINEIKDKDKFDIL
                     WEQITIQYAAIIRAQKIMYVKDKEEMIKELKKHESTENGEKIEYEFQFAWDRQASFLN
                     AQSRA"
BASE COUNT         5602 a         1332 c         2378 g         3811 t
ORIGIN      
        1 gatttggagt tgacctacat agaagattga tcaataaaag aagaaaaatg gcagaagaag
       61 gtgtatctga atctaaaaga gagaaagtta acaatttaga tgtaatacaa gatgataaga
      121 aactcataga agggtatgtt gctattgtaa aagatatggc tttaaaatat ggaatatcaa
      181 gtgatttaag caaaaattaa gttaaatcac aacagcactt tgaaaactaa atataaaata
      241 aaaatatctc ccttaaaagt tttttaaaga gagataaaca ctttattttg taactatttg
      301 aatacatgat ggatgaatgc aatagttttt atctttgtaa tttatagaaa cataattact
      361 agagtacatt ttatcaaggt tttcattaat atattcaatt gcattacagc catttataga
      421 gccaatatca gttatatcaa tccagttatt aaatatctta acataaacaa acttcatgat
      481 aacaccaact ttcattagaa tttaagttaa ttataacatg gtgtactgag ataatgtgtt
      541 aagaaataga tacagaatat tcaaaagagg tgattagatg gaaatagagc aaacaacaat
      601 acgcctgcta aaaagcagac gaaagttgaa tattaatttc tattttggtt aggcgaaaga
      661 cctaacaaaa aatctgtaga tacattaagt ttgttagaaa ttaatattaa agtttctaga
      721 tttggttctc ttgaaccagc ttcataatac tgatatgcac gttctgagat accaaacaaa
      781 ctagcaaatt gcttttgagt catattcatt tgctttctta ctagcttaat attatctttg
      841 aatttagtca taactacacg ctccaataaa aaaataaata aatttcttga cacgaacaat
      901 attagcgtgt aatatataaa acatagcacg aacaatattg gcgtgttaaa taaaaaggag
      961 agggtgaaaa taaataataa tttaaaacta caacgtgaaa aaattggctt aacacaatta
     1021 gaggttgctc aaaaagccaa aataacagag agaagctatc aatattatga agctggcgaa
     1081 cgtctcccaa acattcgtac agctttaaag atagctataa ttttaaatac taattgtgaa
     1141 aaactcttta atgaataata gcataaaagg actcagatta caagaaagga gctttagata
     1201 tgaataattt gcaacttaac aataaaaata caataacaac attagaaatt gctgatatgt
     1261 tagaaatcag acactgggaa gtcttaagga aattagaagg aacagaaaaa acaaaaggaa
     1321 ttattgatat tcttaacgac aacaattttg ttgtggttga ttactttata aaatcaacat
     1381 atttggattc aaaaaatgaa agtagacctt gctataatgt aacaaaatta ggttgtgact
     1441 ttctagcaaa taaatttact ggagaaaaag gtattatttt tacagctaga tatgtaagaa
     1501 gatttaatga aatggaacga gtattaaaag aacaacaacc taaactacca actacatata
     1561 aagaagcatt gcaacagtta ttagtagaag ttgaagaaaa agaacaatta caattagaaa
     1621 atcaagaaaa agataaggta attcagttac agcaaccaaa agtactgttt gctgatgcag
     1681 tttcagcttc aaacaattct atattagttg gagaacttgc aaaacttata aaacaaaatg
     1741 gagtagatat aggacaaaac agattattta cctggatgcg agaaaatgga tatttaatta
     1801 agtgtaaagg tgaagattat aatattccaa cacagaaaag tatgaatcta agaataatgg
     1861 aagttaaaaa aagagtaatt aataatcctg atggaagtac taaagtaact agaacagtaa
     1921 aaataactgg aaaaggtcaa gtttattttg ttaataagtt taaaagtagt aaacaattat
     1981 caatgttaag ttaaatcata acagtacctt gaaaactaaa tacagaatat tttggaaagg
     2041 agagattgaa ttggaaaata agaaaataga agaaatagag aaaagaataa ccatgcttga
     2101 aaatcaattg caagcacagt tatttagtca gataacagct caatcaaata gtgattttat
     2161 agattatatg taccaatgta tagttttgta tttacatgag atgaataaaa gtgaaaaaag
     2221 aaaaattagt gaaattacta aagaaagaat cagaaaataa gaatgataat tacaatataa
     2281 aacctattct tctagcaggt tttgaagggt cagttttctt tactgaagtt atcataaagt
     2341 ttatctgtga tgtgtgttga agaatttcag aataaactcc atttactatg ccgtagtagt
     2401 gaattagaca agggttatga taacctactt cttcaacaat cattaataca tcttttccaa
     2461 agttagtcaa ttttagtgca atttcatgtt catcatcaag ttctttttca aattcctcta
     2521 tagatttaag aataatttta tattgaaatt cagcatagta aaaatactct gtgttagaag
     2581 tatcagagac tgtctttctt atactttctt gtaattcttt agatatattg tttgaaaact
     2641 gcataataca ccatcctttt gaaaattttg gaatttattc catgtttata ttataccatg
     2701 tagaactgag gtgaatacaa tgttaatagg cgacaatata aagcaaatac taagaaaaag
     2761 agatataaaa ccttataaat tagcaaagga attaaatata gatgtaagtg gtctatataa
     2821 attgttgaag aataaaaatt ctaatccaac tatagatact ctaataaaat tagctgatta
     2881 tttagatatt acattagacg aattagttgg aagataaata tttgaaaaga ggggagagaa
     2941 ttttaacatg gatatttctg aaagtataac aaagcaattt agtgatagtt taaaaagttt
     3001 aatagaaata gagataaata aacaagagac agatagagtt aagagtcaaa ctgttgaaca
     3061 aaaggtaaaa gtactggagc ctaaagatat agttgtttta ataaaaagag gttatccaaa
     3121 ttacttgata acagtagaag aagcaagggg aattttaaaa ttagatacag tttttatgcg
     3181 taggttagtg agcacaggtt tgataaaatc actggctaga ggtgatggta gaaaaatttc
     3241 aagatatgaa gttgatgatt ttattgaaag aaatcaaggt aaaaatttgg atgaactttt
     3301 aaaagcagta gagagggggg atgaaattgt taagccttaa tactaataag aataacatag
     3361 taactcttaa aaaagatgga aaagttatag cagacatagt atttaaagat attaaaactg
     3421 gtaagaaaat atcggttgga gtattaaata aaaaagtgct ggtcaaataa ccaacacaca
     3481 aaaaaataaa aaataaaata taacacaaac aaattatagc acaaaaagaa tggatttaga
     3541 ataggtaata taacattcta aaaggtttaa tgtgtaataa ttgtagcaat ttagaatgta
     3601 gcttatatag atagtaataa attgggaggg atttaaatgg aagcagctag actaatagca
     3661 ataggtcaaa ttaaacaagc agaaaaagaa atatgtaaat tacaaggtac aaaaaataat
     3721 agtagtttaa tgtggtggga agccgtaaaa tttgctagtc aaaatatatt agagggtctt
     3781 gaacatgaca ttgagttaga agcttctatt gagtttagag aagctatgat gtatcaagaa
     3841 gaacttgaaa aagatagacc aatagatgtc cagatataaa aaaagagcct tcgcacaggc
     3901 tctaagtgaa aataagttac aaaaattata ggtatattat aacataaggg ggaataaatg
     3961 aaaacaaaaa atgaaataat taaggattta gaagatagat tatttttatt aagatttaca
     4021 acagtagatg aagtagattg ggatgtaaaa tttggacaaa tatcagcatt agaattttgt
     4081 atagataaac atagaaaagg atgcactttg caacaattca aagaaaattt agaagaatac
     4141 aaattacaag ggaactatgg tgattatata gatggttttg tgtcagtttt agaaagaaat
     4201 attagagaaa tggagggaga aattgatgga agtgaataat atttacataa aattgatgga
     4261 tgtaagaatt aagtttaaca aattagatat aaaaaagagt ggtcaaaaca agtttgctaa
     4321 ctttaaatat tttgagttag cagacttctt acctcaagca acagagctgt tacaagaagc
     4381 taaattatgc cctatagtga cctttacaaa tgattatgca actctaacat tgattaatgg
     4441 agagaaacca acagaagaga taatatttac ttctccaatg agagaattac aattaaaagg
     4501 ctctaatgag ttacaagcat taggaggaat tgaaacatat cagacaaggt atttgtacat
     4561 tcagttatta aacattacag aaaatgatac ttttgatgct actagtggaa aagaagatta
     4621 taaaagaaat gacttaacaa actcctctat taaagcaagt gaaaatggtc aaataaaaat
     4681 aagtcaaaat caaataaaaa gactgttttc aataggaaat acaataggca aagattcaga
     4741 tagagtaaaa agtgaagtgt attataagtt taataaagaa gttaaagatt taagtaaaca
     4801 ggaatatgac cagatatgtg ttggatatga gaaattacaa agggaaaaag gaataattaa
     4861 gtaggtgaat ttcttgaagg acagagacaa agcaactata gagaaaggaa atatacttag
     4921 tgatgggtat ggtctttcac cacaattggt agctagagat tcatggctaa caacaggagc
     4981 aagagcttta tatttctatc tatccagttt tgcaggagca agtgggacat gttatccatc
     5041 tagggatatt atgactcatg aacttggtat aaataaagat acttttagta aatacctaaa
     5101 tgaactaaag acgagtggtt atataaaagt atataaaaat aaaactaggg aaggaaggat
     5161 gcaaaataat atatatgagg tagtatttga tagaagctat atagaaagtc atatatccat
     5221 tagatgtaag aaagaaaata aaaaaaaacc atgtccgaaa aaagcagaca tggaaccatg
     5281 tccgaattta ccggacatgg ttcaaccgga catggaaaag tcggacacta taagtaacag
     5341 tattataaat aacagtttta aaagcagtat gtatatagag caagctgtgg ataactcttt
     5401 aaaagaattt aagaagctat atgaagaaaa tataggagta gtatatccag tcacagctga
     5461 atggttatta gaagtatcta atgaagtaga tataagagta tttaaaagag ctatagagat
     5521 atgtgctgaa agaatgaata tgaatttatc atacttaaag ggaatcctta aaaagtggaa
     5581 ggatgcaaat ataactacat atgaacaatt agagtcatat aaattacaac atgaaaataa
     5641 aaagtcaaaa aaaactaata gtgtagtaag caaaaataag tttgctaatt ttgaacaaac
     5701 atttactcaa tacagtaaca aagaattaga tgaaattata aagaaaagcc aaaaggctaa
     5761 atttaaataa tattgatgga ggtattaaaa tgaatcaagt tgtattagtt ggaagattaa
     5821 ctagagaccc agaactcaaa tacataccag gaacaggtac agcagtagca tcatttacaa
     5881 tagctgtaga cagaaattat ataaataaag aaggaaaaag ggatactgat tttataccaa
     5941 tagaagtaat aggtaaatca gctgaatact gtgcaaatta cataacaaaa gggaaactag
     6001 tagcattaga agggaatata agagttgaca attataaaac tcaatcaggt gaaaaaagaa
     6061 catttataaa agtcagtaca aaatcagtac aatcattaga aagcaagagt aaatcgagta
     6121 attcatataa agagagtgta caagatggaa caataggact agaccctcaa ggatttgaaa
     6181 ttatagatga tgatgagtta gcattttaat ctgaaaatta aatatgaggt gaaataaatg
     6241 tttaaagtag aaaggtattt tagtggctca gtagtggaca accttattga agatgacctt
     6301 acatgtagaa actacttagc attatattgt tgtttgctgg gaattacaaa aaatggaaaa
     6361 aagatatatc ctaagccaga aaaaatgtta gctgagtttg gagtaaagaa ggacagaaaa
     6421 ataaaaaaag agttaccagt aagaattaga aatgttaata caggggaagt aaaacaattt
     6481 gagtctatag atggtgcagc ctgtttttta agattaaaat atcaagcagt ttatcaagct
     6541 attaaaaaga aaagtaaaac tagaagtggc tggaaagctg aatatattga ggaggaataa
     6601 tggaagtttc aaggacagaa tatacaatta aaagagcaaa agagttatat gacaatggag
     6661 aggatatatt tattgctata gataaggcta gagaaaaata tgaggagatg attaaaagtg
     6721 aatatcttag ctagtgtgat attagtaata ggaagtttta tagctggtag agtttatgag
     6781 tatagattga acctaaaagg gtgtgaaaat tgtgataata agaaggtgca aatatgaatg
     6841 tattaagtct attcgatgga attagttgtg gtcaagttgc ttttgagaga gctagaataa
     6901 aagtagaaaa ttattttgca agtgaaataa aagagattgc gattaaagta gcaatgaata
     6961 attacccaaa aacaatacaa cttggagatg taagagagct aaatgtaagt aaaatcccta
     7021 aagtagatat tcttattggc ggaagcccat gccaaaattt aagtaaagga agattaatag
     7081 ctaataaaat acaggatgga ttaactggag ataaaagtaa tttgttttgg gaatatataa
     7141 gaattctaaa acaattgaat ccagaatatt ttcttttaga aaacgtagtg atgcccaaaa
     7201 aagatgaaaa catgataagc caattgttag gagttgaacc aatcaagata aatagcaatt
     7261 tagttagtta tcaaaataga gacagattat attggacaaa tattttaaat gttcaacaac
     7321 ctaaagattt aaaaattagt tttcaagatt ataaagatac tagttttgat tattgcaaag
     7381 agtttgaaat taaaaaaact ccaagtagag aaaaaatgtg gggtaatggt ttaaatggaa
     7441 attgtaagaa tgtaacatat gaagacaaaa taaactgcgt aacattaaaa caagatagat
     7501 ttagtaattc aggtttagta gaatttgggt ctttctgcag atacttaaca actagagaat
     7561 tagagttagc gcagacgcta ccagttggat atacaaaagg tttgagtata agacaagcac
     7621 aaaatgtcat aggtgatggt tggacaatag atgtgatagc acatatttta tcaaatatta
     7681 actagttctt tatatataaa ttattattga agcggttagc tatcatgata cttgtagcag
     7741 taagttttat agctggtagg gtttatgagt atagattgaa tctgaaagag tgtgaaaatt
     7801 gtaataacaa ctatcctgaa aaatgagaaa gaagtggttt tatgaataaa agaataattt
     7861 gcaattggtg tggtaaatta ttttacatcc caaaacagtc taaaaaaatt tactgttgta
     7921 aaagatgtga gagaaaggct aagaaaagca atagagaaca gcaaaattaa ttttaaacaa
     7981 taaaactatg ggggaatagc aatgaataag tttcaaaaag cagtttctca aatggtgaaa
     8041 caagaggaaa aagaaaactt attgcaagga tatgagaatt gtatagtagg cagaagtata
     8101 tcaagctcca taagaagata tgtgaaaggg tttaaaaagt ttggatatag tgtacatgag
     8161 gtttatgaat ttatagatga tattaataag tatgagtaat ttttaagtga taaagggagt
     8221 atttgattga gtaaatacaa taataagaaa attgtaatag atggaattaa atttgatagt
     8281 aaagatgagt cagagtatta tttatattta aaagaaaaaa aggaaaatgg agaaataaaa
     8341 gactttggac ttcaacaaaa gtttgaacta caacctaaat ttaaaaaaga tggaaaaagc
     8401 tatagagcta ttacatatac agttgatttt gccatataca aatggaatgg tgaagtcgtt
     8461 tatatagatg tgaaagggta tagtacacag cagggtgaac ttagaaaaaa gctttttgac
     8521 tataaatatc aggacaaaaa attgatatgg attgctaaaa gcaaaaaata tggggtagat
     8581 ggttggatag aatatagtga acttaagaaa aagagaaaag aaaataagaa aaaggtagct
     8641 taaataaata ggagtgatgt tatggcaagt aaagttaaaa aggagttttt tatggcaact
     8701 aaaaaacacc ttgagaacta caaacaacta catattaata ttgaaagtct aaaacttcaa
     8761 ataaaaaatc tcaaagagtt ccatttaggt gattttatgc aaggtttaag ctatgacagc
     8821 attcccataa gtaagactaa ttcaataagt aatcaagttg aaaatgagtt aattaatctt
     8881 gaagaaaaga taatagaaaa gcagatagaa ttatatgaaa tggaagcact aaaatataca
     8941 atagatgtat ccataagtaa tttaaaacct atacataaac aaattataag gtataggtat
     9001 attgaaggct tagaatggag tttaatagtt gataaagtat acttagaaga aagacaatta
     9061 agagaaagag ctaatcaagc cattagttca atatcaatag ccttatttgg taaaaaagca
     9121 ttaatagagc aagaaccatt atttaagatg ttagatttat aggcagttaa taactgtcta
     9181 ttttttttgt gaaaaagata tatggaagtt attgacaata tcacgcatac gtgatattat
     9241 tgaagtatag aaaggaggcg aaaagaaagt ggctaagaaa ataaaagagt tcagaaaact
     9301 cataaaagaa ttaactgaac tcgtactcga agttggcaca ctattagcag tcatcaaaat
     9361 ggtaatagat agcctacatt agtaaaatgt taagagtgga agttgcacct tccctcttaa
     9421 ctaaattata aaacatagtc actaaaaata caatgaataa gtatagagag ttaacatttg
     9481 aattattgaa actactgtat gacactatta aattaattgg agcatcaata ttgttatatt
     9541 atgttattaa ctcaattttc tagcaatgat taggaggtat tttatgaatc gatttgaagg
     9601 tatttatagc tttgcagaag caacaaaatt atgggatttg aaagattcta cacttagaaa
     9661 agcagttgcg acaggcaaat tagttgaaaa tattgattgt aaaaagtttg gtcgtgattg
     9721 ggtagtaact attgaagcaa tggaaagaga atatggaaaa ttaaataata taatgaaaga
     9781 cctagattaa attctaggtc tttttattgc cgcttttctg ccgattttac aatttaaaat
     9841 gtgagataat agtattgtgg aaatgaatat ttctctctca aaactaaata tatgtgggct
     9901 aggttaaggg attcgcctag cttatatgaa caaactaggc agggcatgag gatgctgtaa
     9961 gttcaattct tactatgttc aaacttatta atacactata tgtagatatg ctggattaaa
    10021 acggaattta attcaaatgt ctaaaagagt ggggcttggt aacctcactc aatttgcaag
    10081 gactggtgtg taatcttagg ttcgattcct aaaacttgct cccttaaata taatatgtat
    10141 ccccaaaaaa aggcttagat taaattctaa gtcttttttt aataattaat gtagataata
    10201 atatttattg ctaaaatgat gtacaaatat gataatataa attacataaa gatatataaa
    10261 tagaggggga ttataaattt gttaaatgaa aagaatctaa agaacataaa gaatatatta
    10321 caaatggtac aaatgaaaca ccttaaagat tttgaaaatt ggggaattaa taaacgaaaa
    10381 aaagaaactg ctataaatag cttgataaac ataatacaaa atgatggaga aaaactagat
    10441 tattttaagg aatggatatc aatctttaca atagatggtc ataataatta ttatgttttt
    10501 aattacaatg attctgactt ggaattggaa gatttaaaaa acatagtaga agatatagta
    10561 agtgaaaatt tattggagat tgatactagt gatttagaag aaactaaggt catatataaa
    10621 aaaaatgatg tcataaacaa aagattgatt ataagattta tttctccagc tttaattagc
    10681 tgtaaaaatg aaaatgagaa tgggaatata gaatctggat tagaaaaaac tttttatttt
    10741 gcaactttat ttctagactt aagtttgaaa caaataatag tttctatacc acatactgta
    10801 ggtataaaaa gcatagataa tatagaggct aaagcaagag atttctcaga aatagcaaaa
    10861 tattatgtat caaaattaga agatttgtta actacttata atatacaaat agaaaaatac
    10921 aatgattgga tatatgatgc tacatatgag cttgctgagg aaggcagtgc tcataataat
    10981 cctgagataa acaaaaaata tgaagaaaat attgataaaa tagatgaatt cgcaaaaaag
    11041 atagctattg cttctggaat aactgataag gctataatag aaaatttcaa agagggagtg
    11101 ggaatactct atgagaatat tctaatagac gaatttggtg tggtagagga tgaaaatcaa
    11161 tacagtactt ttgtgcaaaa tggtgatgga gtaaattcat actgtagagt tgggtctaaa
    11221 acagcaaccc taaaatcagg aaagggacat gctatagcca agacatctag aaacaatgag
    11281 gatgtcaaga atttaggtgt catgaaatca ttcaatggaa ctttatccag atttttaatt
    11341 gaagtcttag ataaagaatt atatttaata agaacagaca cttctaaatt tatagaagag
    11401 agggtgattt atgatgttat acgaaaagtt ggagaatata agtatacttt taggaaatca
    11461 gagtaaagca aaatctataa tagaagaatt agagaaatta atgaagagtg atatcattac
    11521 accaagattg ctggccagga aaactaaagt tacactttta gaggctacaa gagttcttga
    11581 atttttagtt aaagaaaatg aattagaatt ttttattgtt gttgaatgtt ctaatccaga
    11641 tagcatatat gaaaatgaga taggtcacta taaatacttc acttcgataa aagaattcaa
    11701 tgctttttca aaaggacaag aatgcccaat atgtggatgt ggttataaat acaactttga
    11761 agatacaaaa ataggcttta gaagattgga gaagtgatac agtgagtcta gataccttaa
    11821 aagaatatct aagcatatgt gatgataatt taatttggga gcctttttat gatgacagta
    11881 tgctattaga cgaattctct aattatataa aagaaataga attatctaag gaatggaata
    11941 aatctaaaaa tcatgagaaa ggaaaaattt tagaacaatt agtaagattt ataatgtcta
    12001 gatttacaat attaagtgat atatctgtaa ataagtctac aacagataat gagctagatg
    12061 tttttgttaa gtttaatgac aacataccaa taccattctt atgtaatata aaatcaaaaa
    12121 tagtatgtga atgtaaaaac tggaaaagta gaaaagtgga tgtaggaatg gtatctaaac
    12181 tagcagaaat atgcaataaa aataatgcgg gattgggcat atttatttct ttaaatggat
    12241 tgacaggtaa gggttggcaa tatgctgaag gaaaaagaag aaaattatat ttatcagata
    12301 agatgccaat aatatcgttt acagtagatg aaataacgaa attaaagtat aaaaggtata
    12361 atcttctgac tatgataaaa tgtaaaatgc aagcattaat agatgagatg gaatttgctg
    12421 gaggagaatt aagattatta gaaagtgaac ttggatttat agactgttta aatgaaaata
    12481 tagaatcttt gaaaatgttg ggtttaataa ccgaagttga atataacaat attaaagtaa
    12541 gaatcaatca tagatatgat attgtaaact gagaactcca aacgagttct ttttttattc
    12601 ccaaaacgac aaacaaacga ggtggtggtg tgcaagatgt gaaagaaaaa gtaaaacaag
    12661 attacctaaa aggtatgaaa caaaaggaaa tatcagcaaa gtatgacatt agtttaaata
    12721 ctttaaagtc atggataaaa agatacaatt gggctaatga gaaaaagaag ggtgcaccta
    12781 aaaataaaag aggtgcaccc ataggtaata aaaatgccac tggtcctcct ggaaataaga
    12841 atgctgaaaa atttggtttc ttctcaaaat acttacctga agaaacccaa gacttaatta
    12901 atgagataaa ggataaagat aaatttgata ttctttggga acagataaca atacaatatg
    12961 cagcaataat aagagcacaa aagataatgt atgttaaaga caaggaagaa atgattaagg
    13021 aattaaagaa acatgaaagc acagaaaatg gtgagaagat agagtatgaa tttcaatttg
    13081 catgggatag gcaagcatct tttcttaatg cacagagtag agc
//
LOCUS       DAEORM030000084        12870 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.087, whole genome shotgun sequence.
ACCESSION   DAEORM030000084 DAEORM030000000
VERSION     DAEORM030000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12870)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12870)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 12870)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12870
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.087"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            73..702
                     /locus_tag="KRH23_003444"
     CDS             73..702
                     /locus_tag="KRH23_003444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HHS5226714.1"
                     /translation="MSIKERRKNEKEEMKKKIMDASIEIINQHGYENLSIRKIATKIE
                     YSPTTIYLYYKDKAEIISDMTNKLYNTVESNAIDIMNNCSSLPIDKQIIEIMTSFIKT
                     LSSEPEMAKAIMHSRMNIIFASENTNNTPSNNGIKMLDKFLSIGIEQGIFKKNIDKSS
                     WMLISALLGFVLCVVENKLYSLHNFSQLIENFLDILVGGLYNENSQQGY"
     gene            677..1081
                     /locus_tag="KRH23_003445"
     CDS             677..1081
                     /locus_tag="KRH23_003445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-binding protein"
                     /protein_id="HHS5226715.1"
                     /translation="MKIRNKATNKKKKYVKISIALFFVFICIIIVIVSNLKPENLVVK
                     DIDINNVKNGIYTGSADNNLVKATVSVEVNNGKIQNINILKHDHLLGKPAEKITTSII
                     KQQSLDVDAITSATYSSNTIRKAVENALRKGE"
     gene            1084..1557
                     /locus_tag="KRH23_003446"
     CDS             1084..1557
                     /locus_tag="KRH23_003446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin domain-containing protein"
                     /protein_id="HHS5226716.1"
                     /translation="MNTIIIYSSKYGCTKDCANILKNKLSDNVTIVDINNNNKIELSK
                     FDKIIIGSSIYVGSVSKKIQVLCNDNVELLNKKQVGIFLCCGFSEQADKYLKSNFPSS
                     LLESANAIGIFGSEARLEKMKFLDKLIMKAVSKGNYDSFRISQDNIDNFLINLNS"
     gene            2127..2792
                     /locus_tag="KRH23_003447"
     CDS             2127..2792
                     /locus_tag="KRH23_003447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HHS5226717.1"
                     /translation="MIKLIGILIVVIGFILKIDTLFTVLLAGVATGIVAGLDFNQIFT
                     ILGDSFVSNRGVSLFILTLPVIGVLERYGLKQRAVSLIEKLKRLTTGKVLTIYMIARQ
                     IAGALSIRMSGHPQFVRPLVNPMAQAAGLSNSDELKESDEEAIKALSAASENYGNFYG
                     QNLFAGSSGVLLIASTLTQFGYNVTGLNIVKASTIMAVIALVVATIQFTLYDKKLNKS
                     HKK"
     gene            2814..3746
                     /locus_tag="KRH23_003448"
     CDS             2814..3746
                     /locus_tag="KRH23_003448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HHS5226718.1"
                     /translation="MQNFINISLEIFYALMGFLMIVIAYKSFTTINNNKKYGTSLFWI
                     LISLPFIFGRLIPANIIGIILILSSLLTLSKQVVFAKYEEPDENFGKEQADKLKNKIF
                     IPSLILAFAAVVVAMSLSNFDNSSQFAIGVGSIIALISALIITKAKPATSVQDGSRLL
                     QQMGPASMLPQLLVALGALFTQAGVGEVISTMISGVVPADSRLFGVIAYVLGMVIFTM
                     IMGNAFAAFSVITAGIGIPFVLSQGGNPAIIGALALTAGYCGTLLTPMAANFNIVPAA
                     LLECKNDYIVIKYQAPVALVLIIAHILVMYFLGF"
     gene            3767..4408
                     /gene="pcp"
                     /locus_tag="KRH23_003449"
     CDS             3767..4408
                     /gene="pcp"
                     /locus_tag="KRH23_003449"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016920 - pyroglutamyl-peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HHS5226719.1"
                     /translation="MKILLTGFDPFGGEPINPAQEAVERVNNNINGAEIIKITIPTVM
                     TKSVEAIDKAIQEHNPDIVISVGQAGGRFDITPERVAINIDDFRIKDNEGNQVIDTII
                     KEDGEPAYFSKLPVKAMVKHMNENKIPASVSNTAGTFVCNHVMYGILYMIDKKYPNIR
                     GGFIHIPYTTSQVIDKKNTPFMSLEEIVKGLELAIEACIIYKEDVKEIGGEIS"
     gene            complement(4528..4860)
                     /locus_tag="KRH23_003450"
     CDS             complement(4528..4860)
                     /locus_tag="KRH23_003450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HHS5226720.1"
                     /translation="MSIDCISNTDLSETGFSYTLSLISGKYKMIILYCLVEFEVVRYN
                     ALKRYINTISYKTLSLSLKELEADNLIIRTEYPQIPPKVEYSLSERGKSLIPILDAMC
                     EWGERNRP"
     gene            5125..5745
                     /locus_tag="KRH23_003451"
     CDS             5125..5745
                     /locus_tag="KRH23_003451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HHS5226721.1"
                     /translation="MKVLLINGSPNQYGCTYTALNEITKVLSKHDIKTEILYLGKETI
                     PGCISCASCFETGKCIRNDKVNELIEDLDNIDGIIIGSPVYFSSATGQLTSFLDRLFF
                     IAGSRMATKLGASVVSCRRGGASATFDQLNKYFSISNMPIVSSQYWNQVHGFTPEDVM
                     KDEEGLQTMRTLGENMAWLLKCISAGKKAGIKEPQYEETIMTNFIK"
     gene            complement(6070..6894)
                     /locus_tag="KRH23_003452"
     CDS             complement(6070..6894)
                     /locus_tag="KRH23_003452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraX family protein"
                     /protein_id="HHS5226722.1"
                     /translation="MDFFKKGISGFTIKILALIFMTFDHIAAFMPQTMQIPIWFHWVG
                     RISAPLFIFMAVEGFYHTSNRKKYISRLYIWSVIMAIGNQIINNVFSHPEGAIIINNI
                     FSTLFLIAIYLQAIEFIKKFRKEKEIKYFIIGLLMIIIPIILGIFTVALLFKVTNRVI
                     ALFMILVPVPFLVEGGPIWIILGIIFYLCRGKKFSLSICYVLMCIFIFTTMSNGDYSL
                     KNSILQNYQWMMIASLPLMLLYNGEKGKSMKYLFYLYYPIHVYILYILGIYLINGF"
     gene            complement(6905..8308)
                     /locus_tag="KRH23_003453"
     CDS             complement(6905..8308)
                     /locus_tag="KRH23_003453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HHS5226723.1"
                     /translation="MKWKITRNFIFTIVFVAISVVIINIISILYVISTNSFFKVVDSG
                     NTPEEFARSFEKDLYEKDGEFKLSKIGAEKLEKSNSWIQVLNDLGEEVYGVNVPKDTP
                     KKYTPFQMVNNYKYIETKYVNFVLEKYLNKKHLNIIVGIPSRDISRIILTYSQNNIKK
                     TLNKVIIITLVIDSVVALGVGYLFSRKLTKPISSVLWSIETMANGNYSLYLKDRGIYE
                     EVFKNINMLADTLRVNEVERKENEELREEWLANITHDIKTPLASIQGYAEIINDKDYE
                     FEEDEIREYTEIIYNKSKYIKDLVDDLNLSTRLKDNTIVLDKKKINLVSLVRDIIIDI
                     LNDNRYKNRNIEFESNEDLIEVYVDSILFRRAITNLIFNSIVHNSEGTLISVEIVKKD
                     NIEIIIKDNGIGISKSDLKHIFKKYYRGTNTGEMHKGSGLGMAISKEIIEIHKGKIYV
                     SSEIGIGTKIIIEIKQN"
     gene            complement(8312..8869)
                     /locus_tag="KRH23_003454"
     CDS             complement(8312..8869)
                     /locus_tag="KRH23_003454"
                     /inference="COORDINATES: protein motif:HMM:NF012698.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HHS5226724.1"
                     /translation="MPDGEGYDICKEIRKTSNSPIIFLSAKTEELDKLLGLAIGGDDY
                     VTKPFSPKEVAFRVKAHLRRLSYFSDVQNESKNLNNNEEKIISFGPYILNESRAELIK
                     DGKSIGLSAKELKILSLFAHNQNQIISKEKLWDKVWGEDYVGFDNTIMVHIRKIREKL
                     EDNPSKPEYILTIKGLGYKLAVKED"
     gene            complement(8983..9729)
                     /locus_tag="KRH23_003455"
     CDS             complement(8983..9729)
                     /locus_tag="KRH23_003455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-methyltransferase"
                     /protein_id="HHS5226725.1"
                     /translation="MLDIQKYQLFNGECIELMETIKDKSVDLILCDLPYGMTNCKWDS
                     IINLEEMWKQYNRIIKNSGAIVLFSAQPFTTKLIYSNIKNYKYSWYWIKNIKTGFAFC
                     KYQPLRCVEDINVFYKKTPLYVPQGLKKLDKPIKKTRKDGERENIYHGGLTDKEYIQE
                     YTNYPNHVLHFNKEANCIHPTQKPIKLLEYLIKTYTRENEIVLDNCFGSGATGVACAN
                     TGRKFIGIELDDTYFKQGKNRIERAYKNNL"
     gene            complement(9789..10613)
                     /locus_tag="KRH23_003456"
     CDS             complement(9789..10613)
                     /locus_tag="KRH23_003456"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008745 - N-acetylmuramoyl-L-alanine
                     amidase activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HHS5226726.1"
                     /translation="MSYNILNIHGGHNPKGKVACGAVGLIDESLEDRKVKNEVISILK
                     ANNKIVYDCTVDNGTSKTDVLKKIVFKCNSHKVDLDISIHFNSGAKDEKGNGKTTGVE
                     VFIYNEKTREVATKICESISKLGFKNRGVKIDKDLYVLRNTKAPAILIECCFVDDRDD
                     VELYNYKSMSKAIVEAILNKKINNDGGKKMHKYTIVYEGEIDKISATIMSWNFKENEC
                     KVCDIKDYVPGQTENLYVVGGGACNKISSITKEHYSKLEGKDRFDTIKKVLSFIGK"
     gene            complement(10616..11113)
                     /locus_tag="KRH23_003457"
     CDS             complement(10616..11113)
                     /locus_tag="KRH23_003457"
                     /inference="COORDINATES: protein motif:HMM:NF016961.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HHS5226727.1"
                     /translation="MENYFTAIKLLVTTISAYVSAKLGILAPLILLLLIEMIADYVSA
                     LLAAKVEKLNNPNNPKLGWSSKKGALGIFKKLGYGLAVVVGMSIDYLIVVLTKELGIT
                     INVDTFFGLLTTIWLILNELLSITENLYRADVRLPNFLQSIVLILKKNVETKINLENT
                     EKRGE"
     gene            complement(11224..12393)
                     /locus_tag="KRH23_003458"
     CDS             complement(11224..12393)
                     /locus_tag="KRH23_003458"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="InlB B-repeat-containing protein"
                     /protein_id="HHS5226728.1"
                     /translation="MLNEEVVKNINKLNNEKDNINLELSKKANKEDLNILIQLLENSK
                     KYTINYNINLPEENSNESVTVPNDMIVLANTEVKLRLPSNTDLNEHKFKGWSLTKDGD
                     VIERCIATSDIALYAIWYKCINVTYELNLPNDFEGSIPTVPIDNNKYILGDKVTPLLL
                     NNYDESNKEYNYKFCGWSLTETGEIIENAAIENEHVQSNSLCLYAVWKKYRYVTYNAN
                     FPTEEYPLNRTGEVPIDTNRYVEGDIVTILQNSENNPLGGEEDKDKFCGWTSDIEKAQ
                     IPVVAQKAEESIIIGKEDVILHGMWGKYRVAYVSNFPAGTGVSGSIPANQYSYLTGAS
                     LIVASNTGNLSAGGYELIGWTTVRNDESTMLNFGDRIVFNKSNIILYGFWRNNGE"
     gene            complement(12421..>12870)
                     /locus_tag="KRH23_003459"
     CDS             complement(12421..>12870)
                     /locus_tag="KRH23_003459"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226729.1"
                     /translation="LAISKSRVNLQAFNKAIWDNRLDSKLETTLLNSSSFTRTFNYQS
                     DSWIKSNTGTNVGAYSQGDVITKPNKIFILKYTTNSDNGTITINADGFVQTGTDGNGS
                     GSPGTFPGIVSHYDSELTCYRRVYFGKVNVQISTTGDYYYGDIFTAK"
BASE COUNT         4529 a         1950 c         1532 g         4859 t
ORIGIN      
        1 gacagtatta aaattaaatt atacaataac agtgtaaatt aacttaacac cgttaagcaa
       61 agaggtgatt atatgagtat caaagaaaga cgtaaaaatg aaaaagaaga aatgaagaaa
      121 aagattatgg atgctagcat cgaaattata aaccaacatg gatatgaaaa tttatcaata
      181 agaaaaattg ctacaaaaat agaatattct ccaactacaa tttatcttta ctacaaagac
      241 aaagcagaga ttatcagcga tatgaccaat aaactttata acacagtaga aagtaatgct
      301 attgacatta tgaataattg ctcatcacta ccaatagata aacaaatcat agaaattatg
      361 actagcttta taaaaactct ttctagtgaa ccagagatgg caaaagctat catgcatagt
      421 agaatgaata ttatatttgc atctgaaaat acaaacaata cgcctagcaa taatggtata
      481 aaaatgcttg ataaattcct ttccattgga attgaacaag gaatattcaa aaaaaatata
      541 gataaaagct catggatgct tataagtgca ttgttaggat tcgttttatg tgttgttgaa
      601 aataaactat attctttaca taatttttct caacttatag aaaatttctt agatatttta
      661 gtgggaggac tttacaatga aaattcgcaa caaggctact aataaaaaga aaaaatatgt
      721 aaaaatatct attgctctat tctttgtatt tatatgcatt attattgtaa ttgtaagcaa
      781 cttaaagcca gaaaacttgg tagtaaaaga tatagatatt aataatgtta aaaatggcat
      841 ttatactgga agtgctgata ataacttggt aaaagctact gtgtctgttg aagttaataa
      901 tggtaaaatc caaaatatta atatcttaaa gcacgaccat cttttaggta aacctgctga
      961 aaaaattaca acaagtatta ttaaacaaca gtctttagat gtggatgcta taacttctgc
     1021 aacttatagc agtaatacta tacgaaaagc tgtagaaaat gctttaagaa agggagaata
     1081 attatgaata ctattattat atattcaagt aaatatggtt gtacaaaaga ctgtgcaaat
     1141 atactaaaaa ataaactatc agataatgtc actattgttg atattaataa taataataaa
     1201 attgagttat caaaatttga taaaattatt attggaagtt ctatatatgt tggttcagtt
     1261 tcaaaaaaaa tacaagtgct atgtaatgat aatgtagagt tattaaacaa aaaacaagtt
     1321 ggcattttcc tttgctgtgg cttttctgaa caagcagata aatatttaaa atcaaatttt
     1381 ccatcatcct tattagaaag tgcaaatgct attggaattt ttggtagtga agctcgatta
     1441 gaaaaaatga aatttttaga taaacttatt atgaaggctg tttcaaaagg taattatgac
     1501 agttttagaa tatcacagga taatatagat aattttttaa taaatcttaa tagctaaaat
     1561 aaaactaatt atttctatga taaattcttt tatttataag taatattgct caaaatagtc
     1621 tttaaacttt atcaaaattt tatttttctt agtgaaatct aatgaaacta gcacttaata
     1681 tatgctttat taatcataac aaatatgttt tattaatcat aacaaaaaga gagtgtctaa
     1741 tgaactaaaa aattcattag acactctctt tttgtatgaa atcaaatata tttttatcat
     1801 ttcaaaagtg aaaaatacac ttgtctctat gtttggcaca ttctcttttt ataatataat
     1861 atctaattta aaacctattt caaatattga catatactta aactatagac ttacaaaatc
     1921 aattcatatt agcttaaaat ataatctttg ttattcaaat tcctatacac aaccattatt
     1981 tactttgata ctttaaaaca tcttccctat tttttattaa attttataat aatagtccta
     2041 ttaacgcaaa tactataaaa agagtttaac tttatccatt aaataaattt aaattaaaac
     2101 atatagaaat ggaaggagaa caatttatga taaaactaat cggtatattg atagttgtaa
     2161 ttggatttat acttaaaatt gacacattat ttactgtatt attagcagga gtggcaacag
     2221 gaattgttgc aggattagat tttaatcaaa tttttacaat tttaggagat tcttttgtct
     2281 caaacagagg tgtatcatta ttcatattaa cattgccagt aatcggcgta ttagaaagat
     2341 atggtttaaa acaaagagct gtttctttaa tagaaaaatt aaaaagactt acaacaggaa
     2401 aagtacttac tatatacatg atagctagac aaatagctgg tgctctatca ataagaatga
     2461 gtggacatcc tcaatttgta agaccacttg ttaatcctat ggcacaagct gctggtttaa
     2521 gtaatagtga tgaactaaaa gaatcggatg aagaagccat aaaggcatta tctgctgcat
     2581 cagaaaacta tggaaatttt tatggtcaaa acttatttgc aggtagtagt ggagtattac
     2641 ttatagcatc tactctaact caatttggat acaatgtaac tggacttaat attgtaaagg
     2701 ctagtactat tatggcagta atagcacttg tagtggctac aatccagttt accttatatg
     2761 ataaaaaatt aaacaaaagt cataaaaaat agttttattt aggaggaata aaaatgcaaa
     2821 attttataaa catatcatta gaaatctttt acgcactaat gggattttta atgattgtta
     2881 tagcatataa gtcttttact accataaata acaataagaa atatggtaca tcattatttt
     2941 ggatacttat atcactgcca ttcatatttg gtagattgat tccagccaat ataataggaa
     3001 taatattaat attatctagt ttattaacac tttctaaaca agttgtattt gcaaagtatg
     3061 aagaaccaga tgaaaatttt ggaaaagaac aagcagacaa acttaaaaat aaaatattta
     3121 taccatcatt aatattagca tttgctgcag tagtagtagc tatgagcctt tctaattttg
     3181 ataattcttc tcaatttgca ataggtgtgg gttcaataat tgcattaata tcagccctta
     3241 taataactaa ggcaaaacct gctacatcag ttcaagatgg ctcaagatta cttcaacaaa
     3301 tgggacctgc tagtatgtta ccacaacttt tagttgcatt gggagcttta tttactcaag
     3361 ccggagtcgg tgaagttatt tcaaccatga tatctggtgt agtccctgct gatagcagat
     3421 tatttggtgt tatagcttat gtattaggta tggttatatt taccatgata atgggaaatg
     3481 catttgccgc attttcagtc ataacggcag gaattggtat tccttttgta ttgtctcaag
     3541 gtggaaatcc tgctataatt ggagcattag cattaacagc aggatattgt ggaactctac
     3601 ttactccaat ggctgctaat tttaatatag ttccagcagc cttgctagaa tgtaaaaatg
     3661 attatattgt tataaaatat caagctccag ttgctttggt attaattata gcccacatat
     3721 tagtaatgta ctttttagga ttttaatata attaggaggt aaaataatga aaattttgtt
     3781 aacaggattt gacccatttg gtggagaacc aataaaccca gctcaagaag cagttgaaag
     3841 ggtcaataat aatataaacg gtgcagaaat cataaagata actataccaa cagttatgac
     3901 aaaatctgtt gaagctatag ataaagctat tcaagagcac aatccagata tagtaatatc
     3961 agttggacaa gctggaggta gatttgacat tacacctgag agagttgcta taaatataga
     4021 tgattttaga ataaaagata atgagggtaa ccaagttata gatactatta taaaagaaga
     4081 tggtgaacct gcatattttt caaaattgcc tgtaaaagct atggttaaac atatgaatga
     4141 aaataaaatt ccagctagtg tttcaaacac tgcaggaaca tttgtttgca atcatgtgat
     4201 gtatggaatt ctttatatga tagacaagaa atatcctaat ataaggggtg gatttataca
     4261 catcccatat acaacttcac aagtaataga taaaaaaaat acaccattca tgtctttaga
     4321 agaaatagta aaaggcttag aattagctat agaagcttgt attatatata aagaagatgt
     4381 aaaagaaatt ggtggtgaaa tttcataata aattttttag tatttttata aattaaaaat
     4441 actaactatt aatttaaata tagactgtga gtagattatt caaacaattt tactcacagt
     4501 ctttttatgg tatctacaga tacaaaatta aggtctattc ctctctcccc actcacacat
     4561 tgcatctaaa attggaatca gagattttcc cctttctgat agactatatt ctaccttagg
     4621 aggtatttga ggatattcag tacgaataat caagttatct gcttctaatt cttttaatga
     4681 taaactcaaa gttttatagg agatagtatt tatataacgt tttaatgcat tatatcttac
     4741 aacttcaaat tctacaagac agtaaagaat tatcatctta tatttaccac taatcagtga
     4801 aagtgtataa ctaaatcctg tttcacttaa atctgtattt gatatacagt ctatactcat
     4861 atattacact ctccttttgg ttagtattga acaaaaatgt gcgtacttgt ttttagaata
     4921 atttataata aaattatagt gtaagaataa ttgaaagtca attttataat aggaggtgta
     4981 tttactaaaa aaaagttatt ttaaatagga ttctaagatt agacatttct atataaattg
     5041 ataatattca tgaaaatcct attttataaa aaataatgtc tcttagaaaa tctattaaat
     5101 aaaattcatt ggaggaaatt tataatgaaa gttttattga taaacggtag cccaaaccaa
     5161 tatggatgta cttatacagc actaaatgag attactaaag tattgagtaa acacgatatt
     5221 aaaacagaaa tactgtattt aggtaaagaa acaatcccag gatgtattag ttgcgcatcc
     5281 tgttttgaaa ctggaaaatg tattcgaaat gataaagtta atgaattgat tgaagatctg
     5341 gataatattg atggtattat tattggttct cctgtttact tttctagtgc aactggtcaa
     5401 ttaacttctt ttcttgaccg tttatttttc atagctggga gtcgcatggc tacaaaatta
     5461 ggtgcttcag ttgtgtcatg tagacgtggt ggtgcaagtg caacatttga ccaactaaat
     5521 aaatattttt caatcagcaa tatgcctatt gtatcatcac agtattggaa ccaggtacat
     5581 ggctttactc cagaggatgt tatgaaggat gaagaaggat tacagactat gcgaactcta
     5641 ggagaaaaca tggcatggct tcttaagtgt atatcagcag gtaaaaaagc tggaattaaa
     5701 gaaccacaat atgaagaaac aattatgact aattttataa aataaataaa aaatgtacta
     5761 atattaatta aaacaaaaca ctaatttata aataaaataa gcataaatgt aggataaaaa
     5821 gcactaaaac agaggtattg aattttatat caaacctctg ttttattatt acattaataa
     5881 ccaaaccatg tataacatca tatatttcta aataaattat aatattatat tctaatgtta
     5941 ttgaaattac aataactgaa tttctgctca taaatttaaa tattctacaa atctcatcta
     6001 aataacaatt ttaatagacc taaaacaatc ctcatattgt tcattttgta ttaaaaatat
     6061 cacttacaat caaaaaccat ttattaagta tattcctaag atatacaata tatatacatg
     6121 gattggatag tataaataaa ataaatactt catactcttc cctttttctc cattgtaaag
     6181 taacattaaa ggtagagaag caatcatcat ccattggtaa ttttgtaaaa tagaattttt
     6241 taaactataa tctccatttg acattgttgt aaatataaat atacacatta aaacataaca
     6301 aatactcaaa ctgaactttt tacctctaca caaataaaaa ataatcccaa gtataatcca
     6361 aattggtcca ccttctacta aaaatggtac tggtaccaaa atcataaata aagcaataac
     6421 tctgttagtg actttaaaaa gtaaagctac tgtaaatatt cctaaaatta taggaatgat
     6481 tatcatcaat aatcctataa taaaatattt aatttctttc tcttttctaa atttctttat
     6541 gaactctatt gcttgtaaat aaatcgctat taaaaataat gttgaaaaaa tgttatttat
     6601 aattatagct ccttctggat gtgaaaatac attattaatt atttgatttc ctatagccat
     6661 aataacagac caaatataca atctacttat atattttttt ctgttactag tgtgataaaa
     6721 tccttcaaca gccataaata taaacagtgg tgctgatatt ctgcctaccc aatgaaacca
     6781 aattggtatt tgcattgttt gtggcataaa tgctgctata tggtcaaatg tcataaatat
     6841 taatgctaaa atcttaatag taaacccact tatacctttt ttaaaaaaat ccatatcata
     6901 tctcctaatt ttgttttatc tctataataa tttttgttcc tattccaatt tcactactta
     6961 cataaatttt acctttatga atctctatta tttctttaga aatagccata ccaagacctg
     7021 aacctttatg catctcacct gtattagtac ctctataata ttttttaaaa atatgtttca
     7081 aatcactttt gcttattcca attccattat cttttattat aatttctata ttatcttttt
     7141 ttacaatttc tacacttatc aaagttcctt cgctattatg aactattgaa ttaaatataa
     7201 gattggttat agcccttctg aataagattg aatctacata tacttcaatt aaatcttcat
     7261 tactttcaaa ttcaatattc ctatttttat atctattatc atttaaaata tcaattatta
     7321 tatctctgac taaactgact aaatttattt ttttcttgtc cagaactata gtattatctt
     7381 ttaatcgagt agataaattt aaatcatcaa ctaaatcttt tatatactta gacttattat
     7441 atataatttc tgtatactct cgtatttcat cttcttcaaa ctcataatct ttgtcattaa
     7501 ttatctctgc atacccttgt atagatgcta gaggtgtctt tatatcatgt gttatatttg
     7561 ccagccattc ctctctcaac tcttcatttt cttttctctc aacttcattt actcttaaag
     7621 tatcagctaa catatttata tttttaaaaa cttcttcata tatacctctg tccttaagat
     7681 ataaactata atttccatta gccatagtct caatactcca tagtacgctt gaaattggtt
     7741 ttgtaagttt tctactaaat aaatatccta cgcctaaagc taccacgcta tcaattacta
     7801 gtgttataat gataacttta tttaaagttt ttttaatgtt attttgagaa taggttaaaa
     7861 ttattcttga tatatctcta ctaggtatac ctactattat gtttagatgt tttttgttta
     7921 aatatttttc tagtacaaaa ttaacatact ttgtttctat atacttgtaa ttattcacca
     7981 tttgaaaggg tgtatatttt ttgggagtat cctttggcac atttactcca taaacttcct
     8041 ctcctaaatc atttaaaacc tgtatccagg aatttgattt ttctaatttt tcagctccaa
     8101 tcttagatag tttaaattct ccatcttttt catataaatc tttttcaaaa gaacgtgcaa
     8161 attcttcagg agtatttcca gaatctacaa ctttaaaaaa actattagtt gaaatcacat
     8221 acaatataga tatgatattt ataattacta ctgatatagc tacaaacaca attgtaaata
     8281 taaaatttct agtaatcttc cacttcatat tctaatcttc ctttactgct aatttatatc
     8341 caagaccttt tattgtcaga atatattcag gctttgaagg attatcctct aatttttccc
     8401 taatttttct tatatgaacc attatagtat tgtcaaatcc aacataatct tctccccaca
     8461 ctttatccca tagtttttct ttacttataa tttgattttg attatgtgca aataaagata
     8521 ggatttttag ttcctttgca gacagtccta tagattttcc atcttttata agttctgccc
     8581 tactttcatt taatatatat gggccaaatg atataatttt ttcttcatta ttatttagat
     8641 ttttactttc gttttgaacg tcactaaaat aacttaatct tctcaaatgc gctttaactc
     8701 taaaagccac ttccttaggg ctaaaaggtt ttgtaacata atcatctcct ccaatcgcta
     8761 gtccaagtaa cttatctaat tcttcggttt tagctgataa aaatattatt ggagaattgg
     8821 aggtttttct tatttcttta caaatatcat aaccttcgcc atctggcaaa ggacttttta
     8881 tacaactata ttttgaactt tgttagttag ctttttctta agtataacaa aaataagtaa
     8941 aaaataaggt aacagatttt gagtgttacc ttattttttt atttataaat tattcttgta
     9001 tgctctttct attctatttt taccttgttt aaaataagta tcatctagtt ctatacctat
     9061 aaattttctt ccagtatttg cacatgcaac accagttgca ccacttccaa aacaattatc
     9121 taatacaatc tcattttctc tagtatatgt ttttattaaa tactctaata gcttgattgg
     9181 tttttgagtt ggatggatac aattagcttc tttattaaaa tgcaatacat gattaggata
     9241 atttgtgtat tcttgtatat attccttatc cgttaatcct ccatgatata tattttctcg
     9301 ttctccatct tttcttgttt ttttaattgg tttatctaat tttttcagac cttgaggaac
     9361 atacaaaggt gttttcttgt aaaatacatt tatatcttct acacatctta gaggttgata
     9421 tttacaaaat gcaaatcctg tttttatatt cttaatccaa taccagctgt atttataatt
     9481 ttttatattt gagtaaatta gcttagttgt aaatggttga gctgaaaata aaactatagc
     9541 tccagaattt tttattattc tattatattg tttccacatt tcttctaaat ttataatact
     9601 atcccatttg caattagtca ttccataagg aaggtcacat aggattaggt caaccgactt
     9661 atcttttatt gtctccatta actcaataca ttccccattg aaaagttgat atttttgtat
     9721 gtctaacata ttgtaaccct cctaattatg tactttataa atctggatat attatttgct
     9781 attatatttt acttacctat aaatgataat acttttttaa tagtatcaaa cctatctttt
     9841 ccctctagct tagaataatg ttctttagta atagagctta ttttattgca agctcctcca
     9901 cctacaacat ataaattttc tgtctgacct ggtacgtaat cttttatatc gcaaacttta
     9961 cattcatttt ctttgaagtt ccaactcata atcgttgctg atattttatc aatttcacct
    10021 tcatatacta tagtatattt atgcattttt ttacctccat cattatttat ttttttattt
    10081 aaaatagctt ctactattgc ttttgacatg ctcttgtaat tatataactc tacatcatct
    10141 ctatcgtcaa caaaacaaca ttcaattaat atagctggag cttttgtatt tcttaaaaca
    10201 tacaagtctt tatcaatttt aacacctcta tttttaaacc ctaatttaga tatactttca
    10261 catattttag ttgctacttc tctagttttt tcattatata taaaaacttc tactcctgta
    10321 gtttttccat ttcctttttc atctttagct ccagaattaa agtgtataga tatatctaaa
    10381 tcaaccttat gagaattaca tttaaatact atttttttca gaacatctgt tttggatgtt
    10441 ccattatcta cagtacaatc ataaactatt ttattgttag cttttaagat tgatataact
    10501 tcatttttta cttttctatc ttctaaactc tcatcaatca gcccaacagc tccacaagca
    10561 acttttcctt ttggattatg tccaccatga atatttaata tattataact catatttatt
    10621 cccctctctt ttctgtattt tctaaattaa tttttgtttc aacattcttt tttaaaataa
    10681 gtacaattga ttgtaaaaaa tttggaagcc taacatctgc tctatataaa ttttctgtta
    10741 tagatagtaa ttcatttaaa attaaccata ttgttgttaa tagtccaaaa aatgtatcta
    10801 catttattgt aatgcccaac tctttagtta atacaactat taaatagtct atagacatac
    10861 caactacaac agctagacca taacctagct ttttgaatat tcctaatgcc ccttttttac
    10921 tactccaccc cagttttgga ttattgggat tgttcaattt ttctacttta gctgctaata
    10981 atgcagacac ataatctgct atcatttcta ttaacaacag aaggattaat ggtgctaata
    11041 taccaagttt tgcagataca taagcactta tagttgttac taataattta attgctgtaa
    11101 aataattttc catatttctt atttcctcct aattttttaa taaaaaaaag aactttttat
    11161 tagttctttt gtatttattc tatttaattt aataaatttg ttaacttttt ttagatttag
    11221 agtttattct ccattatttc gccaaaatcc atataaaata atattacttt tattaaatac
    11281 tattctatct ccaaaattta gcatagttga ctcatcattt cttactgttg tccatcctat
    11341 aagttcatac cctcctgcac ttaaattccc agtattagat gctacaatta aacttgcacc
    11401 tgttaagtac gaatattggt tagctggtat actcccactt acacctgttc cagctggaaa
    11461 atttgaaaca tatgccactc tatattttcc ccacatacca tgcaagatta catcttcttt
    11521 acctattata atactttctt ctgctttttg tgctactaca ggaatttgag ctttttctat
    11581 atcagaagtc cacccacaaa atttgtcctt atcctcttct ccacctaacg gattattttc
    11641 actattttgt aatatagtga ctatatcacc ttcaacatat ctatttgtat ctataggtac
    11701 ttctcctgtt ctatttaaag ggtattcttc tgttggaaaa ttagcattat aagttacata
    11761 tctatatttt ttccaaactg catacaagca taaactattt gattgtacat gttcattttc
    11821 tatagcagca ttttcaatta tttctccagt ttcagtcaat gaccaaccac aaaacttgta
    11881 attatattct ttgttacttt catcataatt atttaatagc aaaggagtaa ctttatctcc
    11941 taaaatatat ttattattat caataggtac agttggaata ctaccttcaa aatcattagg
    12001 aagattcaat tcatatgtaa cattaataca cttataccaa attgcataca aggcaatatc
    12061 acttgtagct atacatcttt caattacatc tccatcttta gttaatgacc agcccttgaa
    12121 tttatgttca tttaaatctg tattacttgg caaccttagt tttacttctg tattagctaa
    12181 tactatcatg tcatttggca ctgtaacact ttcgtttgaa ttttcttctg gcaaattaat
    12241 attataattt attgtgtatt tcttactatt ttccaatagt tgtattaata tatttaaatc
    12301 ttccttattc gctttcttac taagctccaa gttaatatta tccttttcat tatttaattt
    12361 attaatattt tttactacct cttcatttaa caatttatca ccttctttct tatattaaat
    12421 ttatttagct gtaaatatat ctccatagta gtaatcacca gtagtactta tttgaacatt
    12481 cactttacca aaatatactc tacgataaca agttaactca gaatcataat gacttacaat
    12541 acctgggaat gttcctggtg aaccagaacc attaccatct gtaccagtct gaacgaatcc
    12601 atctgcatta atagtaattg ttccattatc actattagta gtatatttta atataaatat
    12661 tttatttggc tttgtaataa catctccttg agagtatgct cctacatttg taccagtatt
    12721 agattttatc caagaatccg attgataatt aaatgttcgt gtaaaactac tagaatttaa
    12781 taatgtagtt tccagttttg aatcaagtct attatcccaa atagctttat tgaaagcttg
    12841 taaattaacc ctgcttttag aaatagccaa
//
LOCUS       DAEORM030000085        12622 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.088, whole genome shotgun sequence.
ACCESSION   DAEORM030000085 DAEORM030000000
VERSION     DAEORM030000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12622)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12622)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 12622)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12622
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.088"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            214..1095
                     /locus_tag="KRH23_003460"
     CDS             214..1095
                     /locus_tag="KRH23_003460"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HHS5226730.1"
                     /translation="MVKKRKKKTVTLTILVVIVIGIFSMAWADMSRKKEMKETQERLK
                     AERLEKERIEKEKNEPIIGAKKEAVKEYGYDAKIVWDKLNKYDYSNNGEKIVFLTFDD
                     GPSTTNTPQVLDILKRHGVRGTFFIKGDSLERKGANEILKRTFDEGNAIAHHSYTHDY
                     KKLYPNRSLNLDTFVNELNKTDEAMKKVLGKNFSSNVVRCPGGYMSWKNMEPLGNYLK
                     EKNMASIDWNALNADAEGKKKNAQELFEHAKKSSEGKEMVVLLMHDTYGKQETVNALD
                     QIITYFKDNGYQFKILI"
     gene            complement(1156..2364)
                     /gene="tyrS"
                     /locus_tag="KRH23_003461"
     CDS             complement(1156..2364)
                     /gene="tyrS"
                     /locus_tag="KRH23_003461"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004831 - tyrosine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006437 - tyrosyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HHS5226731.1"
                     /translation="MKSIDEQMRIIMKGVDDLIDEKELREKLIKSEKEGKPMIVKLGL
                     DPSAPDIHLGHTVVLRKMKQLQDLGHQIVIIIGDFTGKIGDPTGKSKARKALTTEQVL
                     ANAKTYEEQIFKVLDKEKTIVRFNSEWLAKLNFEDVIKLAATITVARMLEREDFKKRY
                     EGQMPISVHEFFYPLMQAYDSIALEADIELGGTDQRFNLLMGRSLQREFGMESQIVIM
                     MPLIEGLDGKEKMSKSLGNYIGIDEEAGIMYQKSMEIPDELIIKYYNLVTDVHPDEVN
                     KIESQLKEGSVNPRDIKMNLAREIVTLYHGEESAKEAEERFKSVFQKGQIPEDIQTIQ
                     VKEDGFDLIEVLVSNEIVKSKSEVRRLASQGGVKVNGEKVEDLSTIVKESELVVQIGK
                     KKFVKIELVK"
     misc_binding    complement(2437..2689)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(2841..3809)
                     /locus_tag="KRH23_003462"
     CDS             complement(2841..3809)
                     /locus_tag="KRH23_003462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2232 domain-containing protein"
                     /protein_id="HHS5226732.1"
                     /translation="MNTTKKLTEAALLSSLFIVVTIIAVSTGFGYAIYLDFIVPVFFC
                     IICLKCDLKYTILSGITSLLIISLVLGNLGTAIWASQSVLLGIMCGYLINKPTMVMDD
                     LVYGSVFGVIVMVFIDIYASTLIGYSFMKEFQGYSKWIYFNGYINFIYYLMIALFPFG
                     MVFCIYLLSLILGNKLHILDSNSLKKFLIFKNFRNLNQFLCCSKKAFYICVSYLAIFE
                     VLKLLNAKVDSVYLKTIFISITYISVYFIIRDSCMSLQNFIIAKFRKLLYARILFLII
                     ILLLFFIFDVTVIGLIIINAFLNKKINIRLSQSNIVNKQINLLIEK"
     gene            3982..4422
                     /locus_tag="KRH23_003463"
     CDS             3982..4422
                     /locus_tag="KRH23_003463"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HHS5226733.1"
                     /translation="MFKIKHFNDLSLDEFYEIAKSRYEVFACEQKIFSLNDYDDIDKS
                     SYHIFLKENGLICAYARIIPKEYSSYNDVSIGRVLVLSSHRRKGLAKQMMDCAIDFIK
                     VNLHENNITLSAQTYIKNLYLSCGFKEISEVYDEAGIEHIKMRL"
     gene            4749..4976
                     /locus_tag="KRH23_003464"
     CDS             4749..4976
                     /locus_tag="KRH23_003464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046914 - transition metal ion binding
                     [Evidence IEA];
                     GO_process: GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FeoA family protein"
                     /protein_id="HHS5226734.1"
                     /translation="MKNLNDIQVKKTVKVEDILSSGNLRERMLALGLTRGAVIDVVRK
                     GPKNNLTVYKIRGSKIALRQEESSLILVSDI"
     gene            5002..7122
                     /gene="feoB"
                     /locus_tag="KRH23_003465"
     CDS             5002..7122
                     /gene="feoB"
                     /locus_tag="KRH23_003465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0015093 - ferrous iron transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HHS5226735.1"
                     /translation="MGLTHNSTKMSSLKDMFDIDNKEDQFVIALAGNPNTGKSTVFNH
                     LTGLRQHTGNWPGKTVATARGNFKYKNTEYALIDLPGTYSLFALSQEEIVARDFICFG
                     NPDAVIVVCDATCLERNLNLVFQVMELTDKVILCINLIDEARKKGITIDKKLLEDSLG
                     IPVILTAARNGSGMDELLDTLNDVSFDKYKLNNKPVRYNENIENVVKSIQPELDNIIP
                     SINSRWLGLRLIDGDESIFESMSNYIDKDSIDAINEVKKKIPDNINKQKIRDEFTKIN
                     YDYAKKLSDECCSNVAKKSTDREEKVDKILTSKIFGLPIMLLLLGTILWITIEGANYP
                     STLLSNLLLGFEPSISGILNSINCPSWLNDMLVLGLYRTLAWVISVMLPPMAIFFPLF
                     TLLEDFGYLPRVAFNLDHLFKKACAHGKQCLTMCMGFGCNAAGVIGCRIIDSPRERLI
                     AILTNNFVPCNGRFPTLIAISTIFFSSVITNSFVSSVATALCITLLIILGVIITLLVS
                     YTLSKTLLKGVPSTFTLELPPYRVPQIGRTLYTSIIDRTIFVLGRAVMVAIPAGVITW
                     IFANIYIGDLSILSHVANFLDPLAKLIGLDGFILLAFILGFPANEIVVPILLMAYLAT
                     GSMIELDSFSALGQVLREHGWTYLTALNVMLFSLLHWPCATTLLTIKKETGSLKWTAL
                     GFLMPTILAFVVCFLTTTVYNLFI"
     gene            complement(7255..8073)
                     /locus_tag="KRH23_003466"
     CDS             complement(7255..8073)
                     /locus_tag="KRH23_003466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HHS5226736.1"
                     /translation="MEKQYFTTGEFAKLCGISKQTLIFYDKIGIFSPEYKDKNNYRYY
                     SVYQYDTLDILQSLREIGMSLEEIKEYIQNRTPQLCVKMLKEEEKKIREKIKKLRKIS
                     SKMQNRINITVEGISKMNSEEIYISKKFEEYLVLSSDLSNMSNSDFMMELIDFTNYCK
                     SKNLYQGYELGVIVSNENIKNGDYLSISSFYLKIDKKIKDKKLYVKPEGMYACIKHIG
                     KYEDSYKSYEKLKKYIYENEYKIIGNSYEESILDFFCESNEDNYMTEISIQVSR"
     gene            8292..8441
                     /locus_tag="KRH23_003467"
     CDS             8292..8441
                     /locus_tag="KRH23_003467"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226737.1"
                     /translation="MKIVIGATIRYLIKHKVNYCNKKSLDKLELKYGNIDREKAVKLE
                     IFNRT"
     repeat_region   8721..9479
                     /inference="COORDINATES: alignment:CRISPRCasFinder:4.3.2"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=8721..8749
                     /rpt_unit_seq="atttacattccatatagttaatataaaac"
     gene            complement(10138..12231)
                     /gene="pdcA"
                     /locus_tag="KRH23_003468"
     CDS             complement(10138..12231)
                     /gene="pdcA"
                     /locus_tag="KRH23_003468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="c-di-GMP phosphodiesterase PdcA"
                     /protein_id="HHS5226738.1"
                     /translation="MNKHNFEVILNQLQINIYVTNIHTNEIIFMNKKMKEEYNILDPE
                     GKVCWQVLYPEKNSTCSFCKVLELLKNDKKGVLIKWYEKCNKLNRVFENYDSLITWQD
                     GTVVHMHQSIDIANSTSLNKPIKINEFHEISNNKEEKGVFNFSRDNFDYNSTLLYDAL
                     IRGTDEYIYICNMKTGVFRYSPSQVELFDLPGEIVENPLVYWKKIVHPEDWNRFYKSN
                     TEIGKNQMDYHTVEFRAKNRSGEYIWLRCRGQLMRDEFGEPSIFAGIMTQLGKQNKID
                     SLTQLLNYHEFMSVFEDKISNPMIEKLCIVLLNIDDFKNVNEMYDRDFGDNIIKTLAQ
                     SIQSILPDNAELYKLDGDEMGILVDNVEENEILTLYNQIQNMIIHLQLWRKYGLNITI
                     SAGCVIYPKHGDTVKELYKCASYSLQYAKEHGKNRLVFFSQEILKNKMYSLEMMRDLK
                     ASINDDFRGFSLRFQPQVDTESHKIIGVEVLLRWTNDKCKAISPLEFIPILEENDMIN
                     IVGAWVLRMALRTFRKWIDYYPFFKVSVNVSAVQILEDTFIEDIVKIIDDENFPYQNL
                     VLELTESHTVQNMSILQFKFKALQDLGIYIAMDDFGTGYSSLEVLKFSPIDIVKIDRV
                     FVKDILKSKFDATFIHFIVAICHDVGIKVCLEGVETQEEYDLVKQIKPDYIQGYLFGK
                     PQTATEIFDLLKLDN"
BASE COUNT         4475 a         1840 c         1510 g         4797 t
ORIGIN      
        1 aatttttata ttttttatat ttttttacct atactaaatt tttttataga tatttttaat
       61 atatatgata ctttaatatt atgcaaataa tgtcatataa gttacacttt agttatctta
      121 gttacaactt tgtcggttta ctttttctac tttcttcgat ataattataa tatatttttg
      181 atacaattcg acaaaagggg gaatgctgta attatggtaa aaaaaagaaa aaagaaaact
      241 gttacactta ctatacttgt tgtaatagtt attggtattt tttctatggc atgggcggac
      301 atgtctagaa aaaaagaaat gaaagaaact caagaaagac ttaaagctga aagattagaa
      361 aaagaaagaa ttgaaaaaga aaaaaatgaa cctattattg gtgcaaaaaa agaagctgta
      421 aaagaatatg gatatgacgc aaaaatagtt tgggacaaac ttaacaaata cgactattca
      481 aacaatggag aaaagatagt ctttcttaca tttgatgatg gaccatctac tactaatact
      541 ccacaagttc tagatatctt gaaaagacat ggtgttagag gaactttctt tattaagggt
      601 gattctcttg aaagaaaagg agctaatgaa attttaaaaa gaacatttga cgaaggaaat
      661 gcaatagccc atcactctta tactcatgac tataaaaaac tatatcctaa cagaagccta
      721 aatctcgata cattcgtaaa tgaacttaac aaaactgatg aagctatgaa aaaagtctta
      781 ggaaagaatt tttcctcaaa tgtagttaga tgcccaggcg ggtatatgtc atggaaaaat
      841 atggaacctc taggaaacta cttaaaagag aaaaacatgg catcaattga ttggaacgct
      901 ttaaatgctg atgcagaagg taaaaagaaa aatgcacaag aattatttga acatgcaaag
      961 aaatcttctg aaggcaaaga aatggttgtt cttttaatgc atgatactta tggaaaacaa
     1021 gaaacagtaa atgcattgga ccaaattata acatatttta aagacaatgg ttatcaattt
     1081 aaaattttaa tataataaaa aagcaagttt attgaatgta cattttatac tcaatagact
     1141 tgcttttact ttactctatt ttactagctc gatttttaca aattttttct ttcctatttg
     1201 aacaactaat tcactctctt ttacaatagt gcttaaatcc tctacttttt caccatttac
     1261 ctttactcca ccttgagaag ctaatcttct aacttcactc ttactcttaa caatctcatt
     1321 agaaactagt acttcgatta agtcaaatcc atcttcctta acttgaattg tttgtatatc
     1381 ttcaggtatt tgaccttttt ggaatacaga tttaaatctt tcttcagctt ctttagcaga
     1441 ttcttctcca tggtataatg ttactatttc tcttgctaag ttcatcttta tatctcttgg
     1501 atttactgaa ccctctttca actgagattc tattttatta acttcatcag gatgaacatc
     1561 tgtcactaaa ttgtagtatt taattataag ttcatcagga atttccatag atttttggta
     1621 cattattccc gcttcttcat ctattccaat atagttacct aaactcttac tcattttttc
     1681 tttaccatct aatccttcta ttaaaggcat cattattact atttgagact ccataccaaa
     1741 ttctctttgt aatgatcttc ccattagtaa attgaatctt tggtcagttc caccaagttc
     1801 tatatcagct tctaatgcta tagagtcata tgcttgcatt aatgggtaga agaactcatg
     1861 tactgatatt ggcatttgtc cttcatatct ctttttaaaa tcttctcttt ctaacattct
     1921 cgcaacagta atagttgctg ctaattttat tacatcttca aaatttaact tggctaacca
     1981 ctcgctatta aatcttacaa tagttttttc tttatctaaa actttgaaaa tttgttcttc
     2041 ataagttttt gcatttgcaa gaacttgctc tgttgttaaa gcttttctag ctttagattt
     2101 tccagttggg tctccaattt ttcctgtaaa atctccaatt attattacta tttgatgacc
     2161 taaatcttgt aattgtttca tctttctaag aactactgta tgccctaaat gtatatctgg
     2221 agcacttggg tctagaccca attttactat cataggcttt ccttcttttt ctgatttaat
     2281 aagcttttcc cttaactctt tctcatctat taaatcatct acacctttca taattattcg
     2341 catttgctcg tctatcgatt tcatttttca ttcctcctaa aatatttata taatctataa
     2401 tttttatttt tataataaaa aaagctttca tcctcttaaa aggacgaaag cattgcttac
     2461 gtgttaccac cttagttcat caatatctca cgatattaat ctcttagagt acaattacat
     2521 atactcgtgt actataacgt gtactaatcc gatatctctt aatggttgtt atctttcaga
     2581 gatagtgctc tgagatgtat tcaaactaaa tcaatttatt ccatttcacc aaactggaac
     2641 tctctgttaa ataaaatata gccctacttc ttctcttcat agcatttata tattcagatt
     2701 atttcatcaa ttacaagaaa tttttcttaa cttactcata atatattatt atttttatat
     2761 tttgtcaacc ttttttatta ttatatacat gtttttttac attatactac ttttttatat
     2821 tttttaccaa tacccaaaat ttatttttca atcaaaagat ttatttgttt attgactata
     2881 ttactctgac tcaatcttat atttattttc ttatttaaaa atgcgtttat aattattaaa
     2941 ccaataactg ttacatcaaa tataaaaaac agcaataaaa ttattatcaa aaataaaatt
     3001 ctagcatata ataattttct aaacttagct attataaagt tttgtagtga catacatgag
     3061 tctctaatga taaaatagac acttatatag gttattgata taaagattgt ttttaaataa
     3121 acagaatcaa ctttagcatt caacagtttt agaacttcaa aaatggctag ataagaaaca
     3181 catatgtaaa aagctttttt tgagcaacat aaaaattggt ttaaatttct aaagttctta
     3241 aatattaaaa atttttttaa agaattagaa tctaaaatat gcaatttatt ccctaaaatt
     3301 aaacttaata aatatatgca aaacaccata ccaaaaggaa acaatgctat cattaaataa
     3361 taaataaaat ttatataccc attaaaataa atccatttgc tatatccttg aaattctttc
     3421 ataaaactat aacctattaa tgttgaagca tatatatcaa tgaaaaccat tacaataacc
     3481 ccaaatactg aaccatatac taaatcatcc ataaccattg taggcttatt tattagatag
     3541 ccacacatta taccaagtaa tacactctga cttgcccaaa tagcagttcc tagatttcca
     3601 agtaccagag aaattattaa aagcgaagta attccagata aaatggtata ctttaaatca
     3661 catttcaagc agattataca aaaaaatact ggcactataa aatctaagta aatagcatat
     3721 ccaaatccag tactcacagc tataattgtt actactatga ataaagatga caataaagct
     3781 gcttcagtta attttttagt agtattcaaa acactgcctc cataaatcat aaattttcta
     3841 actaaagttt tgtttttaat atagtatatc actttttaaa aatattttta ataaatataa
     3901 attttaataa aggtatttat gttaaaaatg gtataatgta tcttaatatt cagtttttta
     3961 agatgctagg aggtaattac tatgtttaaa attaaacact ttaatgattt gagtttagat
     4021 gaattttatg aaatagcaaa atcaagatat gaggtatttg cttgtgaaca gaagatattt
     4081 tcattaaacg attatgatga tatagataaa agctcttatc acatattttt aaaagaaaat
     4141 ggattgattt gtgcttacgc tagaataatt cctaaagaat acagctctta taatgatgtt
     4201 tccattggta gagttttagt tctttctagt catagaagaa aaggattagc aaaacaaatg
     4261 atggattgtg ctatagattt tataaaagtt aacttacacg aaaataatat aaccttatca
     4321 gcacaaactt atataaagaa cctttactta tcttgtggtt ttaaagaaat ctcagaagta
     4381 tacgacgaag caggtattga acatattaaa atgagattat agtgttgaca agctaatatt
     4441 gttaatatat aatttaagta taaattaaat attgaattga tatttaggta tttgaaaata
     4501 ccttacatag agtcagaagg cttttgcttt ctgacttttt tattatcaaa attcaataat
     4561 tatatggatt caaagtgtta atttttattc tatattctac tttccccaaa agtaagaatt
     4621 atacccaact ttgtatgata ggcatcttgc ctatcttttt tttgtaaaag taacaaggta
     4681 ataatataat gcatagttta aaataagaag attagcccag gctaaatttc aagcatggag
     4741 gtgctactat gaaaaacctt aacgatattc aagtgaaaaa aactgtcaaa gttgaagata
     4801 tattatctag tggtaattta agagaaagaa tgttagcgct tggtcttact agaggagctg
     4861 ttatagatgt agttagaaaa ggtccaaaaa ataatttaac tgtctataaa atcagaggta
     4921 gcaagatagc tctacgacaa gaagaaagta gcttaatatt agtttctgac atttaaaaat
     4981 ttctagcagg aggatattaa tatggggttg acacataact caactaaaat gagttcttta
     5041 aaagacatgt ttgatataga caataaggaa gaccagtttg taattgcatt ggctggcaat
     5101 ccaaatacag gtaaaagtac tgtatttaat catcttacag ggcttagaca gcatactgga
     5161 aactggccag gaaaaactgt agctacagct cgtggtaatt ttaaatataa aaataccgaa
     5221 tatgcattaa tagatttacc aggaacatat tctttatttg ccttatcaca agaagaaatt
     5281 gtagctcgtg attttatatg ttttggtaat ccagatgcag taatagtagt atgtgatgct
     5341 acatgtcttg aaagaaattt aaatttagta tttcaagtga tggaacttac agataaagtt
     5401 attttgtgta ttaatttaat agatgaagct agaaaaaaag gcattactat tgataaaaaa
     5461 cttttagagg attctcttgg tattccagtt attttaactg ctgcaagaaa tggctctggt
     5521 atggatgaac tattggatac tttaaatgat gtatcttttg acaaatataa attaaataat
     5581 aaacctgtta gatacaatga aaatatagag aatgtggtaa aatcaattca accagaattg
     5641 gataatatta taccaagtat aaattctagg tggttgggac ttagacttat tgatggcgat
     5701 gaaagtatat ttgaatctat gagtaattat atagacaaag attctataga tgctattaat
     5761 gaagtaaaga aaaagattcc agacaatata aataaacaga aaataagaga tgagtttact
     5821 aaaatcaact atgattatgc taaaaaactg agtgatgagt gttgttctaa tgttgctaaa
     5881 aaatcaactg atagagaaga aaaagtagat aaaatattaa catctaaaat atttgggctt
     5941 ccaataatgc tcttattatt aggtactata ttgtggatta ctatagaagg agctaactat
     6001 ccatccactt tattatctaa tttattactc ggatttgagc caagtatttc gggtatatta
     6061 aatagtatta attgtccatc atggttaaat gatatgttgg ttttaggatt atacagaaca
     6121 ttagcatggg taatctctgt aatgctacct cctatggcaa tattttttcc attatttacc
     6181 ctacttgagg attttggata tttgccaaga gttgcattta acttagacca cctatttaaa
     6241 aaagcttgtg cacatggaaa acagtgtttg actatgtgta tgggatttgg atgtaatgca
     6301 gctggagtta ttggttgtag gataattgac tctccaaggg aaagacttat agctatactt
     6361 acaaacaact ttgttccttg taatggtcgt tttcctactt tgatagctat atctacaata
     6421 ttttttagct cagttataac caactctttc gtatcaagcg tagcaactgc actttgcata
     6481 actttactga taattctagg tgttataata acattgttgg tttcttatac tctttctaaa
     6541 acgctattaa aaggagttcc gtctacattt acattagaac ttcctcctta tagagttcct
     6601 caaataggaa gaactttata tacctctata atagatagaa caatatttgt tttaggaagg
     6661 gctgtaatgg tagccatacc tgctggtgtc ataacttgga tatttgcaaa tatatatata
     6721 ggagatttaa gtatattatc acatgttgca aactttttag accctttagc taaattaatt
     6781 ggtcttgatg gttttatatt acttgctttt attcttggat tcccagcaaa tgagatagtt
     6841 gtacctatac ttttaatggc ttacctagca actggttcta tgatagaatt agatagcttt
     6901 agtgctttag gtcaagttct tagagaacat ggatggactt atttgacagc tttaaatgtt
     6961 atgctgttca gtttactgca ttggccttgt gcaacaacac ttttaacaat aaaaaaagaa
     7021 actggtagtt taaaatggac tgccttagga ttcttaatgc ctactatact tgcttttgtt
     7081 gtttgttttt taacaactac agtttacaat ttatttatat aattagtatt aactgacagt
     7141 agacatatat tagagaaact atttaaaaat ttatatactt tattataaag catagagata
     7201 tattcaatga taagtaaaat tacttaacat ttgaatatat ctctatttta attcttatct
     7261 ggatacttgg attgaaattt cagtcatata attatcttca ttactttcac aaaaaaagtc
     7321 aagtatactc tcctcatacg aatttccaat aattttatat tcattttcat atatatattt
     7381 tttcaatttt tcgtaagatt tatatgaatc ctcatatttt ccaatatgtt ttatgcaagc
     7441 atacattcct tctggcttta catatagctt tttatccttt atttttttat ctatcttcaa
     7501 ataaaaactt gatatactta aatagtcccc attttttata ttttcattac ttactattac
     7561 tcccaactca tatccttgat acaaattttt cgatttacaa taattggtga aatctattaa
     7621 ttccatcata aaatcactat tactcatatt actcaaatcg cttgatagaa ctaaatattc
     7681 ttcaaacttt ttggatatat aaatttcttc actattcatt ttagaaattc cttcaactgt
     7741 tatatttatt ctattttgca tcttagaact tatctttctt agttttttta ttttttctct
     7801 tatctttttt tcttcttctt taagcatttt cacacaaagc tggggagttc tattttgtat
     7861 atactctttt atttcctcta aactcattcc tatttctctt aatgattgta atatatcaag
     7921 tgtatcatat tgataaactg agtaatatct ataattattt ttatctttat attcaggaga
     7981 aaaaatacct attttgtcat agaaaattaa tgtctgctta gatataccac acaatttagc
     8041 aaattcacct gttgtaaaat actgtttttc caagggttat acactccttt tctttttgtt
     8101 gtctatatag ttactatatt ctttattatt tactaaatca agtagttatt attttagaaa
     8161 atcaatatgg ttttgatttt aaagcttaaa tatcagttag atgtcagtta taaatatttt
     8221 acccattccc atcataaaaa agatatcccc tcttaacttt tggatggaat attatattta
     8281 tacttgttag agtgaaaatt gtaataggtg ctacaataag atatttaatt aaacataaag
     8341 ttaattattg taataaaaaa tctttagata aattagagtt aaagtatgga aatatagata
     8401 gagaaaaagc tgttaaacta gaaatattta atagaacttg aatatataga aatgagttta
     8461 ttaataagaa gattagatac tgcaataaca tcattagcat tagtatctat tataacaata
     8521 gcatcatatt atttaatcag aaaaaatgtg taattatgta agctatttat aataaaacac
     8581 tgataaaatt aataataaaa aggtaatagg atttctatac taccttttgg tttttataat
     8641 atagtgtaat tttattatat ttttgtatgc taatataact agataatcat aagataacac
     8701 attaaaagaa aattataaaa acttacattc tgtatagtta atataaaaca taagtaatat
     8761 aaatttatgt aaagcaacaa aagatggatt tacattccat atagttaata taaaactagc
     8821 tacattatct gtttcagcag tcgcaatgac atatacattt acattccata tagttaatat
     8881 aaaacacagg aggattaggg tctggagacg ggtctggact atttacattc catatagtta
     8941 atataaaacc ttagctgata tatcacttaa actagcgtct gtttgcaaat ttacattcca
     9001 tatagttaat ataaaacagt ttaggaggtt agtttctgtg atatattttt atagatttac
     9061 attccatata gttaatataa aactggtttt actgcttgga taatttctta tgtttttacc
     9121 atttacattc catatagtta atataaaact catgttatta gctttaataa attatgaaaa
     9181 atacatattt acattccata tagttaatat aaaacaatta gatgcttttg ttaaagaaca
     9241 tgcaacgtac gtatttacat tccatatagt taatataaaa cgctgttgac cctgctcctg
     9301 ttttgccctc gatagattaa tttacattcc atatagttaa tataaaactt gcagagtaaa
     9361 gagactgaaa tagtgacttt ttataattta cattccatat agttaatata aaacgtacga
     9421 gtatatagtt gctatggaac cacaaggtcg atttacattc catatagtta atataaaacc
     9481 ccaaaataaa cttagtattt tcaatactta cacgtataca actctcttaa atttgcagtg
     9541 aacgagcaat agtgcaattg ataacgctta tcattcactc tcaacgcctt atatttcaac
     9601 tgttacgcca aattttttca caaatatcgc tcactgcaaa attcctataa ttttattata
     9661 tcataaatat attacttttg aatattgata ccaatttata ccataataaa agcaaaaaaa
     9721 cgtaatctat ctacattaga tttaaattct ataacttaaa gttttttaca taatatttat
     9781 gcttgtttaa tcaatctaat atatcattct tgtatattgc ttttaatagt cttttttctt
     9841 aaataaatat ctatctgaac aagcatagtt taattaaaaa cttttgtatt cccttaaaac
     9901 tgtatctacc tcttattatt ttatttatga tatattattt ttaatctaaa aatagatatc
     9961 tatttttatt atggttatcc ctttttaaaa tactttaatc atatactatt cccaatttaa
    10021 catccattga aatgctattt tcttatattg caatttataa ttgatatatc ttcaatataa
    10081 taatttaatg tatttttgat tttaaagctt ttcagtgata ttattgataa attagaatta
    10141 attatctagc tttaaaaggt caaagatttc tgttgctgtc tgcggttttc caaataaata
    10201 tccttgtatg taatctggct ttatttgttt aactaaatca tactcttctt gtgtttctac
    10261 accttctaaa catactttta ttcctacgtc atgacaaatt gcaacaataa aatgtataaa
    10321 tgtagcatca aacttactct ttaatatatc tttaacaaat actctatcaa ttttcactat
    10381 atctattgga gaaaatttta aaacttctag agacgagtat cccgtaccaa aatcatccat
    10441 agcaatataa attcctaagt cttgtaaagc cttaaattta aactgtaaaa tactcatatt
    10501 ttgtactgta tgactttctg tcaattctaa aacaagattt tgataaggaa aattttcatc
    10561 atctataatt tttactatat cttcaataaa tgtgtcttct aatatttgaa cagctgaaac
    10621 gtttacactc actttaaaaa aaggatagta atcaatccat ttcctaaaag tacgtaatgc
    10681 cattcgaagc acccaagccc ctacaatatt tatcatatca ttttcttcta atattggaat
    10741 aaattccaaa ggagaaattg ctttgcattt gtcattagtc caccttaaaa gaacttctac
    10801 acctattatt ttatgacttt ctgtatctac ttgtggctgg aatcgaagac taaaccccct
    10861 aaaatcatca ttaattgatg cctttaaatc ccgcatcatt tctaatgaat acattttatt
    10921 ttttaatatt tcttgggaga aaaaaacaag cctgttttta ccatgctctt tcgcatattg
    10981 taaagagtaa ctagcacact tataaagttc ttttactgta tctccatgtt ttggatatat
    11041 tacacaacca gcagaaattg ttatatttaa tccatatttt ctccatagtt gaaggtgtat
    11101 aatcatattc tgtatttgat tatatagagt tagaatttca ttttcttcaa cattatcaac
    11161 aagaataccc atttcgtccc catcaagttt ataaagttca gcattatctg gtaaaataga
    11221 ttgtatagac tgtgctagtg tttttattat attatctcca aaatccctat catacatctc
    11281 attaacattt ttaaaatcgt caatatttaa taatactatg cataattttt caatcatagg
    11341 atttgaaatt ttatcttcaa atacactcat aaattcatga taattcagta actgtgtcaa
    11401 tgaatcaatc ttattttgtt tacctaattg cgtcattatt cctgcaaaaa tacttggttc
    11461 tccaaattca tcacgcatta gttgacctct acatcttaac catatatatt ctccactacg
    11521 atttttagcc ctaaattcca ctgtatgata atccatctgg tttttaccta tttcagtgtt
    11581 tgacttataa aaacgattcc agtcttctgg atgtacaatt tttttccagt aaacaagcgg
    11641 attttcaaca atttctcctg gtaagtcaaa taattcaact tgtgatggtg aatatcgaaa
    11701 tacgcctgtt ttcatattgc aaatgtatat atattcatct gtacctctaa tcaaagcatc
    11761 ataaagcaat gtagaattat aatcaaaatt gtctcttgaa aaattaaaaa ctcctttttc
    11821 ttctttatta tttgatattt catgaaattc attaatctta attggtttat ttaagcttgt
    11881 tgagtttgca atatctattg attgatgcat atgaacaact gtgccatctt gccatgtaat
    11941 taaactatca taattttcaa aaacacgatt taacttatta catttttcat accactttat
    12001 taatactcct tttttatcat tctttaataa ttctaaaact ttacaaaaac tacaagtaga
    12061 atttttttca ggatataata cttgccaaca aacttttcct tctggatcta aaatattata
    12121 ttcttctttc atttttttgt tcataaaaat aatttcatta gtatgaatat ttgtaacata
    12181 tatattaatc tgtagttgat ttaatataac ttcaaaatta tgtttgttca tatacttatc
    12241 tcctccatag ttactgctct ttataacaac attgttaaaa ttattctttt tagaagattt
    12301 acttataact tatacatata cactaaatac cttaatttaa ttagaaagtt tattacttca
    12361 tattttaaat tataattgat aaaaaaaaat acagcaatat agtattacca atttaaaaaa
    12421 aattaatatt acataataca tctctctctt atattaaatt ttaacgtggt actaatcttg
    12481 acaaattgtc cacaaaaata aattatatat tttattattg ttttaaattt ttataaaaaa
    12541 tcagtattat tgatactatt gaagttaaaa agcattaatt tctaaaaaca ttataatttt
    12601 tctaatagac ttaatcactt tt
//
LOCUS       DAEORM030000086        12611 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.089, whole genome shotgun sequence.
ACCESSION   DAEORM030000086 DAEORM030000000
VERSION     DAEORM030000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12611)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12611)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 12611)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12611
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.089"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            complement(661..1395)
                     /locus_tag="KRH23_003469"
     CDS             complement(661..1395)
                     /locus_tag="KRH23_003469"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HHS5226739.1"
                     /translation="MNLAKGLDVLKISSNVFSEDKVMYIPVIYTEDDATLIDTGLPGQ
                     GDLIIDALNKSNTSFDRLKNIIITHHDIDHIGNINYLREKSKNNIKVYAYKSEISYIT
                     GEETPFKLYMLEQMVDKIDDKMLSMLNVMGLGFKSSYTKVDVSLDNHEKLNLGEEIEV
                     IHTGGHTRGHICLYLKESKVLIAGDLLQVENGELKPVDVMHSNKQELKDAIKNISNYD
                     IETIVFSHGGLYQRNIIETLKNLIIE"
     gene            complement(2409..3047)
                     /locus_tag="KRH23_003470"
     CDS             complement(2409..3047)
                     /locus_tag="KRH23_003470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 transporter permease"
                     /protein_id="HHS5226740.1"
                     /translation="MLIHLVKKDILIVKKYVLLILFIAIGIPLFILWRLPPFAQILGF
                     VLSIIFSEFMLCQYLLLKESQYSKASVLLCSTPYPRRGLVQSKYVLFAMVFIYCTLVY
                     WIENLLIPQIGTFDLTYILIVLLISSIIYGVYMPIQYKLGYETTKFFFVVIIMASSFV
                     LPLTMAHSNFEIPFIYQYPSMIVNIVLFLLSLIILLASMFISIKIFSNKELV"
     gene            complement(3050..3922)
                     /locus_tag="KRH23_003471"
     CDS             complement(3050..3922)
                     /locus_tag="KRH23_003471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHS5226741.1"
                     /translation="MRRINMENILEVYNLNKTYTDFSLSNISFALPEDCITGFIGVNG
                     AGKTTTIRSILDVIKRDSGKIKIFGKDFDGNEKELKNRIGVVFDDSYFYEDLSMAEMK
                     SIIAPSYDNWCEEDYQQNMKRFNLNPKQKIDTLSKGMKMKFALALALSHKAEFLIMDE
                     PTSGLDPLIRSQILDILTEYMKKCGRGVFFSTHITSDLDKIADMIVMIDNGRIILERE
                     KDTLLDEHRKVKGDIQFLNDETKKLFLNLEITGYGFIGITSKINEVQKNMPDILIERP
                     TIEDIMLAYIERRE"
     gene            complement(3909..4283)
                     /locus_tag="KRH23_003472"
     CDS             complement(3909..4283)
                     /locus_tag="KRH23_003472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HHS5226742.1"
                     /translation="MKVLISNTSDKPLYQQIKEQIKEAIFTEELKEGDAMPSIRNFAN
                     DLKVSILTIRRVYEELENEGFLTRQVGIGTFISTGNLEILRDSKRRIVEQKMADMIKD
                     AKALGITQIELQEMMDILYEED"
     gene            complement(5447..6637)
                     /locus_tag="KRH23_003473"
     CDS             complement(5447..6637)
                     /locus_tag="KRH23_003473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HHS5226743.1"
                     /translation="MSDMLLWFSVVLVLFAIGDLIASKTKAKVSAVFVTLLLFLILFV
                     TKAIPADIIEKAGMTAAASWSVPMIMFSMGTMLNVKQFIDEWRTVLTAWLGIVAVIVC
                     VSLCIPLFGKSTVLTSIPVINGALPATTIMTQAALEKGLTLAAATATVVFAIQKFIGT
                     PIASRAALQEANRLLVEYHEAKSKGIDLANVDTDKKEAENTGTKVKQAFCEKYDKYYS
                     TNVCIFFIALFSYLGYELSEIIHVNYSIVCLVVGVIVTRIGIVPKDILEKGKIKGFIN
                     MVVFAAVIPSLAKVSLTDLISLFVPIVGMFAASIIGIFLMMKVLPGWKIIGSKPLAFG
                     VGFCQMLGFPTTYLISNEVCNAVGETEEERAYLMSKIMPKLVVGGMACMISIVVAGLM
                     VPML"
     gene            complement(6653..8608)
                     /locus_tag="KRH23_003474"
     CDS             complement(6653..8608)
                     /locus_tag="KRH23_003474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="HHS5226744.1"
                     /translation="MEKIKIENSDIFEYIFPHDISCSPDGKHIAYIISNINEEKDCYE
                     HDLYVMDIKTEKQIHMTQTKDVTSFSWISNTELLFTSKRNKPKAGTTDFYTISIEGGE
                     AKKAFSIPKACSVPVSLGNKLWLLTTKNPTDSKKSEPDRAVEGVDYWTFTDKPFIRDG
                     ENFSQRRRVTLELYQEGENITKAITPKFCEVAGVDVSSDKNRILYTGQIYEDCATPFS
                     GLWEYHIDSGETKELVPQGKYQISLAKYIGKDKVMLQASTLDRSITQNHDIFILDLST
                     SEINMIASPDGMYATLLDVDAVYGGGRSNKVIGDKFIGARICRTMTEFNEFDTKTGNI
                     RIITKVDAFTSFDIYDNTMYTVMLKDYELAEIYSIDMTTGTMKKMTAFSKPYLDTHKV
                     SLPEKLTFVAKNKEEVDGFVIPPIDAKEGEKYPAVLFIHGGPKWAYGYMFTHLKQCVT
                     SKGMYVIYCNPHGGDGYGEKFLEMVERWGYVDYEHLMEFVDTCIEKYPGIDADRLGVA
                     GGSYGGYMTNWIIGHTDRFKAAVSQRGISNLITASLIIDFGDRIMKQTCGDKTPWNHE
                     EVLWNHSPIKYVKNVKTPTLFLHSDRDYRCFMGDTFQMFTALKQLGVDTEMYLFHGDT
                     HGLSRNGRPSNRIARANAIVDWFERYL"
     gene            complement(8625..10670)
                     /locus_tag="KRH23_003475"
     CDS             complement(8625..10670)
                     /locus_tag="KRH23_003475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="HHS5226745.1"
                     /translation="MKKITKERIENTMKKLFTSETFLEYQFISDCQISPDGGYTAFIV
                     KKADIKENGYTSQVYILNNKTGELKQITSINSVGAYAWEDENTILFPALRNEKVKEAV
                     KNGKQCMSYYALSLNGGEAEELFRLPIKGGKLNPIGKGLYAVVDSYDNDRPIVEGLPE
                     EEQQKKINAYNKRYYEHFKEIPYAVNGEGYISRKRKRLYIYDSNINELKAITAPMFNV
                     VGMKISDGKILYIGQEFKDVKGLKNGVYVFDTNTNTNVCILEKDKYIIKGFELYQNQV
                     ILNLTDALSYGNGENGDFYTIDIDTKEMKLLSEHQHHCIGNTVTSDVKMGAGQTTKVD
                     GEYIYYTSTVDMDCIIERIHIPTGKQEKVTQTGSVDFIDVKDSNIVCVGCLGNGLPEV
                     YTVENGTLCKKTHLNDHILQEYKISVPEYIESKGSSKWEIQGYVYKPIDYEVGKKYPA
                     VLAIHGGPRLTYGPYFMHEMQVFASAGYFVFFCNPRGSEGRGNAFADIRKQFGDIDYI
                     DFMEFTDTVLEKYTDIDKTKLAVEGGSYGGFMTNWIIGHTNRFAVACAQRSIANWSGM
                     EGTTDIGYYFCKGQTGASHMEDHELQWKQSPLAYADKCVTPTLFLHGEKDYRCYMQEA
                     FQMFSALKIHGCPTKLCLFEGENHELSRSGRPKQRLQRLVEMLDWFSVYIKKDNIGQ"
     gene            complement(10993..11643)
                     /locus_tag="KRH23_003476"
     CDS             complement(10993..11643)
                     /locus_tag="KRH23_003476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HHS5226746.1"
                     /translation="MKVKSNLDEILYHKIIESLIRGEYSVGQKILLNDLCEKFEVSRT
                     PVVQAVKMLNKDGVLTIMTNGKVYVPEYEYDMVKQVCETRTLIETYALEKMMQEEEEV
                     FQQKLDVIKRYSDKCEEYYRQEKSVELALADLELHKAIVEGANNEILNDVYVGIQGRF
                     IVVNYLIRPLKNRNYEGTVQDHFEILKFIEDRDTKKAVDKLRNHIQGTIKRFCEDE"
     gene            complement(12420..>12611)
                     /locus_tag="KRH23_003477"
     CDS             complement(12420..>12611)
                     /locus_tag="KRH23_003477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HHS5226747.1"
                     /translation="RIGRFVMLKQMLENNLPIKIVSWDSEELYRNSLNSCSLGNYVPL
                     IEYLSSLEDFREVYKMLWK"
BASE COUNT         4281 a         2151 c         1427 g         4752 t
ORIGIN      
        1 cataatttaa acatttttct tcactttgca ttatgatata tggtttaaat aatcttcttt
       61 actttgtatt atgatacatg atttaaatat ttttactcac tttatattat aatacatgct
      121 ttaaataatc ttattcgctt tgtattataa cacatgcttt aaataatctt attcgctttg
      181 tattataaca cattatttaa atatttttac tcactctgca ttatggtaca ttatttaaat
      241 atttttcttc gctttgcatt atgatacatg ctttaaatat ttttactcac cttgtattat
      301 ggtacattat ctaaatattt ttctttactc tgtattatga tatataactt aaatatttta
      361 cctcactctg cattatgata tatgatttaa atatttttac tcactttgta tactaaagtt
      421 tatttaaagt attttctttc ctattatact atgctgttaa atatttttca actgaagtat
      481 tgtagaacct taaaattact ataaaaaact atatcctaaa atacttgtaa tactacgtat
      541 cacccttaac acttaagtat aattttaaag caaaattctt attacttata tttaattttg
      601 attctacatc tttagatata attttaagta atttaagaaa ttattgtaaa tcatatagta
      661 ctactcaata attaggtttt tcaatgtttc aattatgttt ctttgatata atccaccatg
      721 actaaaaact atcgtttcta tatcataatt acttatattt ttaatagcat cttttaactc
      781 ttgtttgttg ctgtgcatta catcaacagg cttaagttct ccattttcta cctgtaacaa
      841 atctccagca ataagtactt tagactcttt taaataaaga catatgtgac ctctagtgtg
      901 acctcctgta tgtataactt ctatttcctc acctagattc aatttttcat ggttatctaa
      961 tgacacatct actttagtat atgatgattt aaatccaagt cccataacat ttagcatact
     1021 aagcatctta tcatcaattt tatctaccat ttgttccaac atataaagtt taaaaggagt
     1081 ttcttctcct gttatatagc tgatttcact tttgtatgca tatactttga tattattctt
     1141 agatttttct cttagataat ttatgtttcc tatatggtct atatcatgat gagtaattat
     1201 tatatttttt aacctatcaa agctcgtgtt acttttatta agagcatcaa ttattaaatc
     1261 accttgaccc ggaagacctg tgtcaataag tgttgcatca tcttctgtgt agattacagg
     1321 aatatacata actttatctt cactgaatac atttgatgaa atttttaaaa catctaatcc
     1381 ctttgctaaa ttcataattt ttctccttat aattacttaa ttagaggtca atttaattaa
     1441 agaaattgag aaaatgtaga ttttcctcta gttatatttt attaattaaa aattattaat
     1501 acctagtata tcacttaagt tgaaggatta ctcgacttga tttttttgtt attttatggt
     1561 atagtaatta atatagaagt aagtaattgc aagctttgca attactttta tttttttcta
     1621 ataactattt tatttttgat aattcgtata ttcgtataaa attaaaagta aagtaatatg
     1681 gaaaatatga atatagaaaa actttaataa gaaaataaat tatgaataaa taaaagaaac
     1741 gcaatactgt atatagatga ttatttagaa aaataaaatc tcttttaata aaaataagct
     1801 tcaaaataaa cttttagttc ataaagctta ggagtaacta aattgagtgc aagtgtatct
     1861 actgttcaaa ataaatagtt cataaagcac tcttttttat attaaatcaa ttatattttc
     1921 gtcatttcag caatgaaaaa gaagcttatc tctattttga gacagcttct ttttattaac
     1981 ttcctacttt ttattagttt tctaaaattg aaaagcttta tttataggat tccttagatt
     2041 tatattttga cgatataatt ttttaaaaac accttaaaag atggtataca atacacacaa
     2101 tcatactcat aattgaaaaa taatcaatgg aaaataaaat tactgaatat tccctattaa
     2161 aaaatacaaa ttgattcaca agaaacatat aatctataat attatgatgt tactctccca
     2221 caccaagtaa ctttattttc aagtaacctt ttcataccat ctaactttac tcaataaaaa
     2281 tggcaatata aatatgtact ctatttttta cttttaaata tctgacaagc tttatatact
     2341 attggaagta agatacaaag taaaacagcc caatctggta aatgtggcat ataaaattcc
     2401 cccttacctt atacaagctc cttattacta aaaattttaa tagaaataaa cattgaagct
     2461 aacagtataa ttaaacttaa aaggaacaat acaatattca ctatcatgga tggatactga
     2521 tatataaatg gaatttcaaa attgctgtga gccatagtta atggtaatac aaatgatgaa
     2581 gccatgatta tcaccacgaa aaagaatttt gttgtttcat atcctaattt atattgaata
     2641 ggcatataaa ctccataaat aatagaactt attaataaaa caatcaaaat atatgttaag
     2701 tcaaaagttc ctatttgtgg aataagtaaa ttttcaatcc agtaaactaa tgtacaatag
     2761 ataaatacca ttgcaaataa aacatactta gattgaacta agccacgtct aggataagga
     2821 gttgaacaaa gtaatacaga tgcttttgaa tattgactct cctttaataa tagatactgg
     2881 cacagcataa attctgaaaa tataatggat agtacaaatc ccaatatttg tgcaaatgga
     2941 ggtaaacgcc acaatataaa taatgggatt cctattgcaa taaacaatat caacaataca
     3001 tattttttta caatcagaat atctttttta actaaatgaa tcaacataat tactctctcc
     3061 tttcaatata tgcaagcata atatcttcaa ttgtaggacg ctctattaaa atatctggca
     3121 tatttttttg cacttcatta atttttgagg taatccctat aaaaccatag ccggtaattt
     3181 ctaaatttaa aaataatttt ttggtttcat catttagaaa ttgaatatcc ccttttactt
     3241 ttctatgttc gtccaataga gtatcttttt cacgttctaa tataatacgt ccattgtcaa
     3301 tcataacaat catatctgct attttgtcta aatcagatgt tatatgagtg gaaaagaaaa
     3361 caccacgacc acatttcttc atatattctg ttagtatgtc aagtatctga ctacggatta
     3421 gtgggtctaa gccacttgta ggttcatcca taattaaaaa ctcagcttta tgcgataatg
     3481 ctaatgctaa agcaaatttc attttcattc cttttgaaag tgtatcaatc ttttgttttg
     3541 ggttaagatt aaaacgcttc atattttgtt gataatcttc ttcacaccaa ttatcatatg
     3601 aaggtgcaat aatacttttc atttctgcca ttgacaaatc ctcatagaaa tatgaatcat
     3661 caaagacaac tccaattcga ttttttaatt ccttctcatt tccatcgaaa tctttaccaa
     3721 agatttttat ttttccacta tcacgcttta tgacatccaa tattgaacgg attgttgttg
     3781 tttttcctgc tccattaaca cctataaatc cggttataca atcttctggt aatgcaaagc
     3841 ttatattaga taatgaaaaa tcggtataag tcttatttaa gttataaact tctaaaatat
     3901 tttccatatt aatcctcctc atatagaata tccatcattt cctgtaactc tatctgtgta
     3961 attcctagtg cttttgcatc cttaatcata tctgccattt tttgttcaac tatacgtctc
     4021 tttgagtctc ttagtatttc taaatttcca gttgaaataa atgttcctat tccaacttgg
     4081 cgtgtaagaa agccttcatt ttcaagttct tcatacactc gtctaatagt caaaatacta
     4141 acttttaaat cattagcaaa atttcttatg gatggcattg catccccttc tttcagttct
     4201 tcagtaaata ttgcttcttt aatttgctct ttaatttgtt ggtataatgg cttatctgat
     4261 gtgttagaaa tgagcacttt cattttttat cacccccttt ttatcacttt cagtgtgatg
     4321 ttatcatata cacactatac acttagagca cttttttgtc aatataaaag atgtaaaata
     4381 ttactatgac aaaataaata tgaatgaaat attagagatt gttgatagct ataaacactt
     4441 tttaaaacca cataagatag aatgtattaa atatttatta aaagtaagaa ttgaatatct
     4501 aaaaaaaaga ggaatcctgt atgaatgatt tgtttgatga taaattaagt tataaactat
     4561 ttataaaaaa cataaaggaa taaatccatt tctaattaca aacatactaa aaaatttaga
     4621 tagtaataaa tagatagtaa taaatagata gtaataaatg ggatgaattt ataagaattt
     4681 ggatagagga aagagttatt caagagtgta gactagaggt aaactctata ttaaaaaaat
     4741 ttaaatttgg atattatgat gcatggaata tttgcagaag taaccttgct ataagtatag
     4801 aagatttttt tgattataaa agataatact ctaaaatatg aggatttcaa cattcaatac
     4861 tgtgctttaa ataatatcac tccaaaatac catccacctt ttactataat tgaataccct
     4921 aattatttta aaaaagaaaa cattagaaac ggaaaacctt ggatatataa aataaaaaat
     4981 actaacttct aaaacacgaa tactctttga taaataaaac aaaaaataat tttaataatt
     5041 aaaattggct atctcaaact agagataagt ctctttctca cttttaaaac gttgaaaata
     5101 tattcgattt cgtacaaaaa agagtgcctt atgaactaaa aaagttcact ttgaggcact
     5161 ccattttttc tcctcttttt aattctttct aaagattttc caaaaatatt attaaatacc
     5221 ctatttacag ataaatcaag ttaaagtttt gttttagaaa ataaaaataa actgtaacta
     5281 ttagaatagc aaataaaaaa tctgtttctt gataaaatca agattataat gctaaaaaga
     5341 aaatattctt ataataaatt aactaatata aaattcgttt ataaattaat actacttttt
     5401 agcttctcct ataaattaac accacttttt taactttgaa acctatctac aacattggta
     5461 ccataagacc agctaccaca atagaaatca tacaagccat accaccaact accagcttag
     5521 gcataatctt agacatcaaa tatgctcttt cttcttccgt ttctccaaca gcattacaca
     5581 cttcatttga aattaaatat gtagttggga atcccaacat ctgacaaaac cctactccaa
     5641 aagcaagagg tttagaaccg ataattttcc aacctggtaa caccttcatc ataaggaata
     5701 taccaatgat agaagctgca aacataccta caattggtac aaaaagacta attaaatctg
     5761 tcaaagaaac ttttgctaaa gaaggaataa cagctgcaaa cacaaccatg ttgataaatc
     5821 ccttgatttt tcctttttcc aaaatgtctt ttggtacaat accaatacgt gttacaataa
     5881 caccaacaac aagacataca atagaataat ttacatgaat aatctctgaa agttcatacc
     5941 ctagataaga gaatagtgct ataaaaaata tacaaacatt tgtagaataa tatttatcgt
     6001 atttttcaca gaaagcttgt tttacttttg tgcctgtatt ctctgcttct ttcttatcag
     6061 tatcaacatt tgctaaatca atgccttttg attttgcttc atgatattct actaaaagac
     6121 ggtttgcctc ttgtaacgct gctcttgaag ctattggtgt accaataaac ttctgaattg
     6181 caaatacaac tgttgctgta gctgctgcaa gtgttagtcc tttttctagt gctgcttgtg
     6241 tcataatagt agtagcaggt aaagctccat ttataactgg tatgcttgtc aatactgttg
     6301 attttccaaa caaaggaata cataatgaga cacagactat aactgctaca attccaagcc
     6361 atgctgtcaa tactgttctc cattcgtcta taaattgttt aacattcaac attgttccca
     6421 tactaaacat aatcattgga acactccaac tagctgctgc ggtcatacct gctttttcaa
     6481 taatatcagc tggtattgct tttgtgacaa atagaatcaa aaataaaagt agtgtaacaa
     6541 atacagctga tacttttgct tttgttttgc ttgcaattaa atccccaata gcaaataaaa
     6601 ctaatacgac actaaaccat aataacatat cactcataga ataaccccct tattataaat
     6661 atctttcaaa ccaatctaca atagcatttg ctcgtgcaat tctattagat ggtcttccat
     6721 ttctagacaa tccatgtgta tctccgtgaa acaaatacat ttctgtatct acaccaagct
     6781 gttttaatgc tgtaaacatt tggaaagtat cccccataaa acatctataa tccctatcac
     6841 tatgtaagaa caatgttggt gtcttaacat ttttcacata tttaataggt gaatgattcc
     6901 aaagaacctc ctcatgattc caaggcgtct tatctccaca agtctgcttc ataattctat
     6961 ccccaaagtc aataattaaa gaagctgtaa tcaagttact aatacctctt tgagaaactg
     7021 ctgctttaaa acggtctgta tggccaatta tccagtttgt catataacca ccgtaacttc
     7081 cccctgcaac ccctaagcgg tctgcatcaa tcccaggata tttttcaata caagtatcta
     7141 caaattccat aagatgctca tagtcaacat acccccatct ttctaccatt tctaagaatt
     7201 tttcaccata accgtcacca ccatgagggt tacaataaat cacatacatt ccctttgatg
     7261 ttacacactg cttcaagtgt gtaaacatat agccatatgc ccatttaggc ccaccatgaa
     7321 tgaacaatac agcaggatat ttttcgcctt ctttagcatc tataggtggt ataacaaaac
     7381 catcaacttc ttctttattt tttgctacaa acgtcaattt ttcaggtaat gaaaccttat
     7441 gagtatctaa atatggttta gaaaaagcag tcattttttt cattgtacct gtagtcatat
     7501 caatgctata tatttctgcc aactcataat cttttaacat tactgtgtac atggtgttgt
     7561 cgtaaatatc aaaagatgta aaagcatcta cttttgtgat gatacgtata ttacctgtct
     7621 ttgtatcaaa ctcattaaat tctgtcatag ttctgcaaat tcttgcacca ataaatttat
     7681 ctcctataac tttattacta cgtccaccac catatactgc atctacatcc agtaatgtag
     7741 catacatacc atctggacta gcaatcatat ttatttcact agtactcaaa tcaagtataa
     7801 aaatatcatg attctgtgta atagaacggt ctaatgttga agcttgcaac attactttat
     7861 ctttgccaat atattttgcc aaacttattt ggtactttcc ttgtggtaca agttctttgg
     7921 tttcaccact gtctatatga tactcccaaa gtccagaaaa aggagttgca caatcttcat
     7981 aaatctgacc agtatataaa attctgtttt tatcagaaga aacgtctaca cctgctactt
     8041 cacaaaattt tggtgtaatg gcttttgtta tattttcacc ttcttgatat aattctaatg
     8101 ttacacgtct tctttgagaa aaattttctc catctcttat aaaaggttta tctgtaaatg
     8161 tccaataatc tacaccctct actgccctat ctggttctga ttttttagaa tccgttggat
     8221 tttttgttgt cagtaaccac aatttatttc caagtgatac aggtacgcta caagcttttg
     8281 gaatagaaaa tgcttttttt gcttctcctc cttctataga aatagtgtaa aaatctgttg
     8341 tacctgcttt tggcttattt cttttagatg taaaaagtag ttctgtatta gaaatccaac
     8401 taaatgatgt tacatctttt gtttgagtca tatgtatttg tttttctgtt ttgatgtcca
     8461 tcacatataa gtcatgttca tagcagtctt tttcctcgtt gatatttgat ataatataag
     8521 caatatgctt tccatcaggt gaacaagaaa tatcatgagg gaatatatat tcaaaaatat
     8581 ctgaattttc aatctttatt ttttccattt ttatattctc ctttctactg tcctatgtta
     8641 tcttttttta tgtacacaga aaaccaatct agcatttcaa ctaatctttg tagcctttgt
     8701 tttggtctac cagaacgaga cagttcatgg ttttctcctt caaatagaca aagttttgta
     8761 ggacacccat gaattttcaa tgctgaaaac atctggaatg cttcttgcat atagcatcta
     8821 tagtcttttt caccatgtaa aaataaagtc ggtgtaacac atttatcagc ataagcaaga
     8881 ggtgactgtt tccattgaag ttcgtggtct tccatatgag aagcacctgt ttgtcctttg
     8941 cagaaataat aaccaatgtc tgttgtaccc tccatgccac tccagtttgc aatagaacgc
     9001 tgagcacaag caacagcaaa acggtttgta tgaccaatta tccaattcgt cataaatcca
     9061 ccataacttc caccttcaac agccaatttt gttttatcaa tgtctgtata tttttcaagt
     9121 acagtatctg taaattccat aaaatctata taatcaatat ctccaaactg tttcctaata
     9181 tctgcaaaag cattaccacg accttcagac ccccttgggt tacagaagaa tacaaagtaa
     9241 cctgcacttg caaatacttg catctcatgc ataaagtatg gtccatatgt caatctcggt
     9301 cctccatgaa ttgccaatac agctggatat tttttcccca cctcataatc tattggttta
     9361 tatacatatc cttgtatttc ccacttagaa cttccttttg actctatgta ttctggcaca
     9421 gaaattttat attcctgtaa aatatggtca tttaaatgtg ttttcttgca caatgttcca
     9481 ttctctactg tataaacttc tggtaatcca tttcctaaac aacccacaca tacaatattg
     9541 ctatctttta catctataaa atcaactgaa cctgtctgtg ttactttttc ctgttttcct
     9601 gttggaatat gtattctttc aataatgcaa tccatatcta ctgtagaagt gtaataaata
     9661 tactctccat ctacctttgt tgtctgacca gcacccattt taacatcaga tgttactgta
     9721 tttccaatac aatgatgttg atgctctgaa agaagtttca tttctttcgt atcaatatca
     9781 atagtataaa aatctccatt ttctccattt ccataagata aagcatcagt taggtttagt
     9841 ataacttgat tttgatataa ttcaaaacct tttataatat acttatcttt ttctaatata
     9901 cagacatttg tgtttgtgtt tgtatcaaat acatagaccc catttttcaa accttttaca
     9961 tctttaaact cttgccctat atataagatt tttccatcac ttattttcat acctacaaca
    10021 ttaaacatag gtgctgtaat tgccttcaat tcatttatat tactgtcgta tatatatagg
    10081 cgttttcttt ttctgctaat atatccctcc ccattgacag cataaggaat ttctttgaaa
    10141 tgttcataat atcttttgtt ataagcattt atttttttct gttgttcttc ttctggcaat
    10201 ccctctacaa taggtcggtc attgtcataa gaatcaacaa ctgcatacaa accttttcct
    10261 ataggattca atttaccacc tttgataggg agtctaaaaa gttcttctgc ttctccacca
    10321 tttaaagata aagcatagta actcatgcat tgcttaccgt ttttgacagc ttcttttact
    10381 ttttcatttc gcaaagcagg gaacaagata gtattttcat cttcccaggc atatgctcca
    10441 acagagttta tagacgttat ttgttttaat tcgccagttt tattgtttaa tatataaact
    10501 tggcttgtgt aaccattctc tttgatatca gcttttttta caataaatgc tgtatatcct
    10561 ccatctggtg atatttggca atcacttata aattgatatt ccaaaaatgt ttcactcgta
    10621 aatagctttt tcatagtatt ttctatcctt tctttagtaa tttttttcaa actccctacc
    10681 acctctttca ttttttattc taaatttaaa ataaaaaatt ttaaatttaa aataaaaaat
    10741 tttataaagg ttattttttt aggaagcctt ctggcttcct tgtaatattt gtaatttaaa
    10801 gtatatttaa tccatgctta attcatactt aattcatact taatctatac ttagtccata
    10861 cttaatctat atttaattca tacttagact tatttacact atatttagat tatgtttaaa
    10921 ctataattag attatactta gactacattt agcaacttaa tagataagta tatatagtaa
    10981 cttcaaaact tattattcat cttcacagaa tcttttaata gttccttgaa tatgatttct
    11041 tagtttatct actgcttttt ttgtatctct gtcttcaatg aattttaata tttcaaaatg
    11101 gtcttgtact gttccttcat aattacgatt ttttaatggt cgaattaaat agttcactac
    11161 tataaatctt ccttgtatac caacatatac atcatttaaa atctcattat ttgccccttc
    11221 tacaatggct ttatgtaatt ccaaatctgc tagtgcaagt tctacagatt tttcttgacg
    11281 atagtactcc tcgcatttat cagagtatct ttttattaca tctagctttt gttgaaaaac
    11341 ctcttcctct tcttgcatca ttttttctaa agcatatgtt tcaatcagtg ttctcgtttc
    11401 acaaacttgt tttaccatat catattcata ctctggtacg tacactttac catttgtcat
    11461 aatagtaagc actccatctt tatttagcat ttttactgct tgtacaactg gtgttctgct
    11521 tacttcaaat ttttcacaaa ggtcatttag taatattttt tgacctacag agtattcacc
    11581 acgaataaga ctttcaataa tcttatgata taaaatttca tctaaatttg actttacttt
    11641 cactactctc accttatttc tattcttttg ccatattata ttgaattact ggactttaat
    11701 tacttttagt aatattttta aagtagaaat tcttatttga tagtactttt gtactacaat
    11761 ttaaattatt gtactgtaaa tcatgctctt atactataga ttaattcatt gtattgcaaa
    11821 tcaagttatt gtactataga ttaaatcgtt atacttcaaa tcatgctagt gtactataga
    11881 ttaaatcgtt gtacttcaaa ttaaactatt atactataga ttaattcatt gttctgcaaa
    11941 tcatgctagt gtactacaaa ttaaactata aatgtttact atctcttaat aatttgaata
    12001 atatgttaca aaaagtatag caccttttta tttttttcgc aataaataaa aaatttaaaa
    12061 ttttttattt tcttgtatta tcaatttgaa atacgaaaga ttaagactaa tagaattgat
    12121 ttagttaatt gaaaaaaata ggtacctttt atgaaaattc taatgataag catttttctg
    12181 atgtaatggt aaattataaa tgataaaatt aaaaatcact tttagtttta tgaactgtcc
    12241 ccatattaag aaacaactaa gatacataaa aatagttata aatagatagt taaactatat
    12301 ccactatttt atatagttaa aatagtggat atagtccaag ctaagaataa ctaagaaatc
    12361 agcgttaaat accatagaca aaaatatatt tatataaaaa ctttttttgc tacaaacaat
    12421 tatttccata acattttata tacttctcta aaatcttcta aacttgataa atattcaatt
    12481 aaagggacat aattacctaa actacaagaa tttaaggagt ttctatacaa ctcctcacta
    12541 tcccaagata caatttttat aggaagatta ttttctaaca tctgttttag cataacaaat
    12601 ctacctatgc g
//
LOCUS       DAEORM030000087        12430 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.090, whole genome shotgun sequence.
ACCESSION   DAEORM030000087 DAEORM030000000
VERSION     DAEORM030000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12430)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12430)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 12430)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12430
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.090"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            219..1148
                     /gene="glsA"
                     /locus_tag="KRH23_003478"
     CDS             219..1148
                     /gene="glsA"
                     /locus_tag="KRH23_003478"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004359 - glutaminase activity [Evidence
                     IEA];
                     GO_process: GO:0006541 - glutamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HHS5226748.1"
                     /translation="MNTLDETLLKEIISSNKKYTNYGQVASYIPELKNARRNDLGICI
                     IDSENNLYSAGNCSTKFTIQSISKPIVLAMALMDNDWEDVFSNVGMEPSGDPFNSIMK
                     LEINDTKKPCNPMINAGAIVTTSLINGSCLEEKEERMLSFFRKLAKNDNIGINYDVYK
                     SEKMTGDRNRAMAYLLKSDGFIRGNVEDVLDLYFKQCSIEIDSVDLARIGINLANYGV
                     DIENGEHLMSEMVSRIVKTFMMTCGMYDASGEFAIKVGIPAKSGVGGGIMASVPGRMG
                     IGVYGPALDKKGNSVAGVKVLEELSNKLKLNIF"
     gene            1246..1809
                     /locus_tag="KRH23_003479"
     CDS             1246..1809
                     /locus_tag="KRH23_003479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR/SmtB family transcription factor"
                     /protein_id="HHS5226749.1"
                     /translation="MKEVLVLRDLECIKAIAHPRRIDILKAFDKSPLSAKQLSQLLEE
                     PHAKINYHIKMLYKVGILELVEEKIKSGIVEKYYYPSAKNVVIGNRILNFSLDNGEEK
                     EELYISKFENMSEVFYKAAEEDVLENENIVDYHDISLTHDELVELSDTMKSKIDEILN
                     KRQHNVEGSKYDIAMVIVPTLEEECPS"
     gene            2297..3133
                     /locus_tag="KRH23_003480"
     CDS             2297..3133
                     /locus_tag="KRH23_003480"
                     /EC_number="3.1.21.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003906 - DNA-(apurinic or apyrimidinic
                     site) endonuclease activity [Evidence IEA];
                     GO_function: GO:0008081 - phosphoric diester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HHS5226750.1"
                     /translation="MIKLGTHLSIAKGFANAAETAVYIGANTFQFFSRNPRGGNAKEF
                     DEKDIIKFQEIRKENNFAPLLAHAPYTMNLGGTKDDVYEFATRVIDEDIRRMDSLGIE
                     YMCFHPGSHVGGGVDFGIDRIVKGLNNAIKGDENITILLETMSGKGTEIGFKFEQLKS
                     IIDKIEHKEKIGVCLDTCHIFSAGYDIVNDLDGVLEEFDKVIGIERLKTVHLNDSMMP
                     FGDKKDRHAPIGEGKIGLKALIDFMEHPSLKHLPFFLETPFDDEGHKKELKMIKEILS
                     SK"
     gene            3417..4412
                     /locus_tag="KRH23_003481"
     CDS             3417..4412
                     /locus_tag="KRH23_003481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HHS5226751.1"
                     /translation="MRNLGNTNMKIKRVGFGGIPIQRITQDDTNLVINELEKQGINFI
                     DSARGYTISEEAIGIAIEGKRDKFFLATKSMSRDYDSMKRDVEISLNNFKTDFIDLYQ
                     FHNVKEEEYDNLFKDKMAYSALLEAKEQGKIKHIGITSHNLNTIEKAIEDGKFDTIQF
                     PYNIVEGQADEVFKKAHEKGIGIIVMKPLAGGALDNATLAIKYILSKDYIDVVIPGME
                     SVEQVRQNVAVLENLVLDEKDNKEIEEIRNSLGKKFCRRCEYCMPCAVGINIPLSFLC
                     EGYYTRYGLKEWAKEKYEVMDVKPTECIDCGLCESRCPYELPIREMLKTVVEKLG"
     gene            complement(4669..5073)
                     /locus_tag="KRH23_003482"
     CDS             complement(4669..5073)
                     /locus_tag="KRH23_003482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HHS5226752.1"
                     /translation="MIKITIPGRPISKSNFKLHNINGQAWMPSKGKYSKYLAYENMIA
                     GFINQQYQGETVEENLITVLKLFFPNKRMGDLHNYPKSICDGIEKSGIIKNDKQLKPV
                     LLFDFIDKDNPRVEIELYPVSKYDISYNIFEK"
     gene            6153..7067
                     /gene="queG"
                     /locus_tag="KRH23_003483"
     CDS             6153..7067
                     /gene="queG"
                     /locus_tag="KRH23_003483"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0052693 - epoxyqueuosine reductase
                     activity [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA];
                     GO_process: GO:0008616 - queuosine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HHS5226753.1"
                     /translation="MDNKELKAFCNLIGLNCVGVAGVDKYDNLEKILKDRQQKGYLTG
                     MEEPIIENRINPRHIMKDANSIIVCAFPYHINRQEKNKNSNLSKYCHGKDYHIVVKDF
                     LQQICDYISKTVTDFKYKLFADNGPLVDRYLAYLSGIGYFGINNNIITDEYGSYVFIG
                     YIVNNYKFEEDKPLEKSCFKCGKCVKYCPGNAILGNYDMNPKKCLSYITQKKGDLSEK
                     EKVVLKNGKKVFGCDICQEVCPHNVEIPTTHILEFKENIIDYLDYDEIQNISNKEFKR
                     RYGDRAFSWRGRNIIKRNMKIILDKYDD"
     gene            7173..9410
                     /locus_tag="KRH23_003484"
     CDS             7173..9410
                     /locus_tag="KRH23_003484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HHS5226754.1"
                     /translation="MKYNNTSEINPLDYILGQERAVEAMELGLKINNPAYNIYIAGEP
                     GTGKSTYALKVLNEYASKKNTHKDWCYIYNFENPREPIIVELEKGFGRELKKDMEKLI
                     ESLLEDFKNAFESENFEIEKNKLLDEYEIEKDMLLKQIKKYGEEKGFKLKQSKMGIVF
                     IPLKEEEDESDESDEEFYKAKRELENMAIQVVYKIRNLEEIAEKAVLELEEEIAKLVV
                     EPHIKRLCEKYENYDKIQTYLENIKKDIIEYMYLFYLDEEELKDKYDKEHFIKYKINL
                     FVDNGSSKNKESAPVVVEINPSPANLFGKAEYDYANGNIKTDFTKLLSGAFHRANGGY
                     LVLYADQLLKYTMSWEILKKTLQTKKVILETQTAIKPENMPLDVKLVLIGSHYIYDIL
                     YRYDEDFEKYFKVFVDFDSEMDKNEDNEEGIARFIAYQCDKNNLRHFTKSAVEEVIKF
                     STRLSGDLEKLSTKFNKIMEVVIEGSAYAEFRNSEYTEQCDVKKAISEKRKRINRVET
                     HMDESIENGFTLIETEGRKVGVINGLSVLSTGEYSFGRASRITATTSPGSKGIVNIER
                     EVNMSGSIHNKGVLILGGYLSENFAQDLLLSLNAYVCFEQNYGGIDGDSASSAELYVL
                     LSSLSGVSIKQNIAVTGSINQKGDIQVVGGISEKIEGFYSICKTKGLNGEQGVIIPRK
                     NQRNLVLSDEVNDAVRDGKFKIYTVERVEEAIEILTDVKFEEIKKLVKEKLISFSKIQ
                     TVSKE"
     gene            9607..10659
                     /gene="nth"
                     /locus_tag="KRH23_003485"
     CDS             9607..10659
                     /gene="nth"
                     /locus_tag="KRH23_003485"
                     /EC_number="4.2.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140078 - class I DNA-(apurinic or
                     apyrimidinic site) endonuclease activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HHS5226755.1"
                     /translation="MKNVNLKEINEKDVIVEEDINLKGMDKKDVIEKEEVNKKSIDKK
                     DIIEKEEIDKKNVKKVEVQKGIDKMIGKKDEIIDEKDIENFMDIEEDKKSIKVSKKST
                     KKGETEKKTKKSSSNKATQKTSKETKSKSKIKNESANEKDVNKILDELEKLYPDAKCE
                     LNYGTAFELLIATILSAQCTDVRVNKVTSELFKKYNTARDFANLSIEEISKEIKSCGL
                     YKSKSQKIKDTSEQLCELYDGEVPDSLEKLIKLPGVGRKTAGVVLSNAFNHPAIAVDT
                     HVFRVSNRIGIVDEPNPQKTEFALMEAIPKERWSHSHHVLIFHGRRMCKARNPECASC
                     PIKEDCNYYKELNETK"
     gene            10853..11323
                     /gene="trmL"
                     /locus_tag="KRH23_003486"
     CDS             10853..11323
                     /gene="trmL"
                     /locus_tag="KRH23_003486"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008175 - tRNA methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HHS5226756.1"
                     /translation="MSLNIVLVEPEIPQNTGNIIRTCAATGSTLHLVKPLGFSLDDKH
                     LKRCGLDYWDIADIQYYDSFEELQEKYPNSKYFFSTTKAKQSHSDVKYEENCFIVFGK
                     ETKGLPEPLLKANMDTCIRVPMLDVEKARSLNLSNSVAIVVYEALRQIGYPNMR"
     gene            11359..12207
                     /locus_tag="KRH23_003487"
     CDS             11359..12207
                     /locus_tag="KRH23_003487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008289 - lipid binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HHS5226757.1"
                     /translation="MKNLKIICDSLSDVPKDLLDKYDIDIVSLTVILEEREYKDRIDI
                     SGDEFYKRLREENVYPKTSQATYAQFKEIFEKYTNEDREILYIAGSATATGTYQSAVM
                     AKNDVDGKIYTYDSNLLCMGTGLLVIKAGELASEGKSVAEILPVLDELKEKAFVIFSV
                     DTLEYLQKGGRISSTKAAIGSILNIKPILEIRDGLVSQISQVRGKKNVISKMMELIKS
                     NCGDDLSDQIVYIGYSDDFKEKEQLSKVMQDELRPKEIRFFQIGVCIGAHAGPGVTGI
                     ICLKNK"
BASE COUNT         5111 a         1132 c         2308 g         3879 t
ORIGIN      
        1 tagattgcta aattactgga ttattagatt actaaattgc taggttgtta aattattgaa
       61 ttattaaatt attaagctct ttaaactatt taaattgttt gaaaaatgaa ttgattcttg
      121 tagaaaataa ttttaaagta taattttttt taacattgtt ttattatagt ataaacttgt
      181 gctaaaatag aatatataac ataatataag aggtgcatat gaatacgtta gatgagacat
      241 tattaaaaga aattataagt tctaataaga agtatactaa ttatggacaa gtcgctagtt
      301 acataccaga attaaaaaac gctagaagaa atgatttagg aatttgtatc atagatagcg
      361 aaaataatct ttatagtgct ggaaactgta gcacaaagtt tactatacaa agtatttcaa
      421 aaccaattgt gcttgctatg gcacttatgg ataatgattg ggaagacgtt ttttcaaacg
      481 ttggaatgga gccaagtggg gacccattta attcaataat gaaacttgaa attaatgaca
      541 caaaaaaacc ctgtaatcca atgataaatg caggggctat agtaaccact tcccttataa
      601 atgggagttg tttagaagaa aaagaagaaa gaatgcttag tttctttaga aagttagcaa
      661 aaaatgataa tataggaata aactatgatg tctataagtc tgaaaaaatg actggagata
      721 gaaacagagc tatggcttac ttattgaaaa gtgatggatt tatcagaggg aatgtagaag
      781 atgttctaga cctttatttt aaacaatgct caattgagat agattctgta gatttagcga
      841 gaattggaat aaatcttgca aattatggag tagatataga aaatggtgag catttaatga
      901 gtgaaatggt ttctaggatt gtcaagacat ttatgatgac ttgtggaatg tatgatgctt
      961 ctggggaatt tgctattaaa gttggcattc ctgcaaaatc tggagttggg ggtggtataa
     1021 tggcttctgt gccgggacgc atggggattg gtgtttatgg acctgcgctt gacaaaaaag
     1081 gtaacagcgt cgcaggagtt aaagttttag aggagttgtc aaataaactc aaattaaata
     1141 ttttttaaaa tattaagaaa ggattttttt gacaacaaca tataatttaa tatataatta
     1201 aattgtaaag aaatatgaat taaataaatt ttttaggagg ggtcaatgaa agaggtattg
     1261 gtattacgag atttggagtg cataaaggct attgcgcatc cacgtagaat agatattcta
     1321 aaagcatttg acaaatcgcc attgtcagca aaacaattat ctcaattatt ggaagaacct
     1381 catgcaaaaa taaactacca tataaaaatg ttatacaaag ttggtatttt agaattagtt
     1441 gaggaaaaaa taaagtcggg gattgtggaa aagtactatt atccaagtgc aaaaaatgtg
     1501 gttataggga ataggatact taatttttct ttagacaatg gggaagaaaa agaagaattg
     1561 tacatatcaa aatttgaaaa tatgagtgaa gttttttata aggcagcaga ggaagatgtt
     1621 ttagaaaatg aaaatatagt tgattatcat gatatttctc ttactcatga tgaattagtt
     1681 gaacttagtg acactatgaa gtcaaagata gatgaaattt taaataaaag acaacacaat
     1741 gttgaaggtt ctaagtatga tatagctatg gttatagttc ctactcttga ggaggaatgt
     1801 cctagttaga gaattaatta tggattaatt aaagatataa tattagagat tgaacatcaa
     1861 aatttactta ataatcaaaa aatagttttt ggtatgggta aaacaatgat ttttaatctc
     1921 tatttttttg tttttttata cctattgtat ttgtaaataa tatgtatagt gtaagatgta
     1981 tacactatct aagaagtgct tagataatat acaaagtatg taagattata atatttgaaa
     2041 ttgattaaaa tgggtataat taaagtgtaa atattaaaat taaaaattaa tataaattaa
     2101 atcaatgcta gaaatatgtt aaaagaggaa tgagattagt tgggatagaa catcccttag
     2161 agcttacgaa tttttagtga aaaagtacta tcaaatagga atctccatct tcatatgttg
     2221 gctaaatgta gttaaggtgg agtagttcaa aattaaaatt gagtacaagt cgtagtacaa
     2281 ataaaaggag attaatatga ttaaattagg aacacatctt tcaatagcaa aaggatttgc
     2341 taatgcggct gagacagctg tatatattgg tgcaaataca tttcaatttt ttagtagaaa
     2401 tccaagagga ggaaatgcta aagaatttga tgaaaaagat ataattaaat ttcaagaaat
     2461 tagaaaagaa aataattttg caccactgct tgcacatgca ccatatacta tgaatctggg
     2521 tggtacaaag gatgatgtat acgaatttgc aacaagggtg atagatgagg atataagaag
     2581 gatggactca ttaggaattg aatacatgtg ttttcatcct ggaagtcatg taggtggtgg
     2641 tgtagatttt ggcatagata gaatagtaaa aggattgaac aatgccataa agggtgatga
     2701 aaatataact atacttcttg aaactatgtc gggaaaggga actgaaatag gttttaaatt
     2761 tgagcaatta aaaagtataa tagacaaaat tgagcataaa gaaaaaatag gtgtgtgtct
     2821 tgatacatgt catatttttt cagctggtta tgatatagtg aatgatttag atggggtttt
     2881 ggaagaattt gataaggtta taggcataga aagattgaaa actgtccatc taaatgatag
     2941 tatgatgcca tttggagaca aaaaagacag acatgctcct ataggggaag gaaagatagg
     3001 attaaaagca ttaattgatt ttatggaaca tcctagtcta aaacatttac catttttctt
     3061 ggaaactcct tttgatgatg aaggtcacaa gaaagagctt aaaatgataa aagaaatact
     3121 atctagtaaa taaaccttta ttaaaaatat gtgaaatact ccgccctcaa cataattagg
     3181 gtggagatac aatcatgaaa tgtgataatt taaattaatg gatagtaata acaaaaattg
     3241 tatacaaatt aactgggtat aaagtatgat tatattatga atagactgat ataaaatata
     3301 attatattat gaatagtatg taaatatatt gcaaagattc tcataatttg ttgtataatt
     3361 aaagatgaca tatttatatt atataaaaaa ttattaaaag ttaggtgggg aaagatatga
     3421 gaaatttagg caatactaac atgaaaataa agagagttgg ctttgggggc attccaatac
     3481 aaaggattac tcaagatgat actaacttag ttataaatga gttagaaaaa caaggaataa
     3541 actttattga tagtgcaaga gggtatacaa taagtgagga agcaatcgga attgccattg
     3601 aaggaaaaag agataaattt ttcttagcta ctaaaagtat gtccagagat tatgattcaa
     3661 tgaagagaga tgttgaaata agtttaaata attttaaaac tgattttata gatttatatc
     3721 aattccataa tgttaaagaa gaggagtatg ataatctttt taaagataaa atggcttata
     3781 gtgccctttt agaggcaaag gagcaaggta agataaaaca tattggtata actagtcaca
     3841 atttaaatac tatagaaaaa gctatagaag atggaaaatt tgacactata caattccctt
     3901 acaatatagt tgaaggacaa gcagatgaag tgtttaaaaa agctcatgaa aaaggaattg
     3961 ggataatagt aatgaaacct ttagctggag gtgctttaga caatgcaaca ctggctatta
     4021 aatatatact atctaaagat tacatagatg tagttatacc aggtatggag agtgttgaac
     4081 aggttagaca aaatgtcgct gtacttgaaa atcttgtgct agatgaaaaa gataataagg
     4141 aaattgaaga aataagaaat tctttaggta aaaaattctg tagaagatgc gaatattgta
     4201 tgccttgtgc tgtaggaata aatataccat tgagtttttt atgtgaaggt tattatacta
     4261 gatatggatt aaaagagtgg gctaaagaaa aatatgaggt tatggatgtt aaacctactg
     4321 agtgtattga ctgtgggctt tgcgagagta gatgtccata tgaacttcct ataagagaaa
     4381 tgcttaagac tgttgttgaa aagctaggat agattttatt tattgaaatc ggtgtattaa
     4441 atttactccg atttcttttt attagatgtg gtcttatata caaatattaa atttacatag
     4501 ttatagctat tatataaatt taatatttgt ttaatactta ttaaatattt acttaatgct
     4561 ttttaaaaac atttgtttga gtatagacat aacacaatta ttattgttgt attagtatag
     4621 tttcaaatac tggagtatca atataatgtc gaataacaca taaaatcttt atttttcaaa
     4681 aatattatag gatatatcgt atttagatac tggataaagt tcaatttcaa ccctagggtt
     4741 atctttatct ataaaatcaa ataaaagtac tggcttaagt tgtttatcat tttttattat
     4801 tccacttttt tcaataccat cacaaatact ttttggataa ttatgtaaat cccccattct
     4861 cttatttggg aagaataatt tcaagactgt tattagattt tcttcaacag tttccccttg
     4921 atactgttgg tttataaaac ctgcaatcat gttttcgtat gcaagatact tagaatattt
     4981 tccctttgaa ggcatccatg cttgaccatt tatgttatga agcttaaaat tagatttact
     5041 aataggtcta cctggaattg ttattttaat caaatttttc accatcctta tacagtattt
     5101 attataatct gtatatgatt taaaagcaaa ttgttattta aagtgttttt acagagcttt
     5161 tttgtaaaat tttccacttt agatgtagta atataagata agtattttgc ttacaaattt
     5221 taaaatttga tatatgatgg acacattcac attagactat tataagacct tcataatatt
     5281 aataagtata gtttagtaaa gagagtaaaa agaaatccat ataagtcaag taaagactta
     5341 ataaatggca atgtaaatgg gatattaatt ataagaaaaa atcaatcttt ttgcttaact
     5401 atagaaagaa tgtcaaaata taactaatga tatttgaagt tttagagttt atattaaaag
     5461 gtaagaaggt taagtgggta aaaaaggttg aatagattaa aaaggctaag tatctaaaag
     5521 agttagtagg taaaaaagtt aaataagtaa atgaaaaagg ctaagtatct aaaagaatta
     5581 gtaggtaaaa aagttaaata agtaaatgaa aaaggctaag tatataaagg agttagtaga
     5641 taaaaaaatt aaatagataa aaagattaag tatctaaaag cgttagtaga taaaaaaatt
     5701 aaataaataa aaaagactaa gtattcaaag gagttagtag gtaaaataat taaatagata
     5761 aaaagactaa ttatttaaag gagttaagta gataaaaaag ttaaataagt aaatgaaaaa
     5821 gacgaagtat ctaaaagagt tagtaaataa aaaagatgaa gtatctaaaa gagttagtag
     5881 gtaaaaaact aaataggtaa aaagatgaag tatctaaaag agttagtagg taaaaaatta
     5941 aatagataaa aagacgaagt acctaaaaga gttagtaggt aaaaaaatta aatagataaa
     6001 aagacgaagt atctaaaaga gttaagcagg taagaaaatt gaatagctaa aaagattaag
     6061 tatttaaaag agttagtagc tagaaaatgt taaaaagact aaaaaaatta aataaattta
     6121 aaaagtcaat tagattaaaa aggaataatt ttatggataa taaggaatta aaagcatttt
     6181 gtaatttaat aggattaaac tgtgtaggag tagcaggggt agataaatat gataatttag
     6241 aaaagatact taaggacaga caacaaaaag gttatttaac tggtatggaa gaaccaataa
     6301 ttgagaacag aattaaccca agacatataa tgaaggatgc taactctata atagtctgtg
     6361 catttccata tcatataaat agacaagaaa agaataaaaa ttcaaattta tcaaaatatt
     6421 gtcatggaaa ggattatcac attgtagtaa aggacttttt acaacaaatt tgtgattata
     6481 tttctaaaac agtaacagat tttaaataca agttatttgc tgataatgga ccattagttg
     6541 acaggtattt agcttattta tcaggaatag gatattttgg aataaataat aatatcataa
     6601 ctgatgaata tggttcttac gtatttatag ggtatatagt aaataattat aaatttgaag
     6661 aagataaacc actagaaaaa agttgtttta aatgtggaaa gtgtgtaaaa tattgtccgg
     6721 gaaatgctat attgggaaat tatgatatga accccaaaaa atgtttatca tatataactc
     6781 aaaaaaaagg agatttgtca gagaaagaaa aagttgtttt aaagaatggc aaaaaggtat
     6841 ttggatgcga tatttgtcaa gaagtatgtc cacataatgt tgaaatacca acaactcata
     6901 ttttggaatt taaagaaaat ataatagatt atttggatta tgatgagata caaaatattt
     6961 caaataaaga atttaaaagg agatatggag atagagcttt tagctggaga gggagaaata
     7021 taataaagag aaatatgaaa ataattttag ataagtatga tgactaataa taagagtctg
     7081 tttcatatac tttaatgtgt atttacttta acacttgttg tgtaaaagtc atattatatc
     7141 attaaagtta aatatgggga ggtgggggaa tattgaaata taataataca tctgaaataa
     7201 atccactaga ttatatattg ggtcaagaaa gagctgtaga agctatggaa ttagggttga
     7261 aaataaataa tccagcgtac aacatatata tagctggtga acctggaact ggtaaaagta
     7321 cttatgcctt aaaggtttta aatgagtatg catccaaaaa aaatacgcat aaagattggt
     7381 gttatatata taattttgaa aaccctagag agcctattat agttgaatta gaaaaggggt
     7441 ttggaagaga acttaagaaa gatatggaga aattaattga aagtctttta gaagatttta
     7501 aaaatgcgtt tgaaagtgaa aattttgaaa tagaaaaaaa taaacttctg gatgaatatg
     7561 aaatagaaaa agatatgctt ttgaagcaaa ttaagaaata tggagaagaa aaaggattta
     7621 aattaaaaca gagtaaaatg ggaatagttt ttatcccttt gaaagaagag gaagatgaaa
     7681 gtgatgagtc tgatgaagag ttttacaaag ctaaaagaga actagaaaat atggcgatac
     7741 aggtcgtata taaaattaga aacttagaag aaatagctga aaaagcagtg ttagagcttg
     7801 aagaagagat agctaaactt gtagtagaac ctcatatcaa gagattgtgt gaaaaatatg
     7861 aaaattatga taagattcaa acttatctgg aaaatataaa gaaagatata atagaatata
     7921 tgtatttatt ctatttagat gaagaggagt taaaagataa gtatgataaa gagcatttta
     7981 ttaaatataa aattaaccta tttgtagaca atggaagctc aaagaataaa gaatcagcac
     8041 ctgttgtagt agagataaac ccaagtccag caaatctatt tggaaaggca gagtatgatt
     8101 atgcaaatgg aaatataaag actgatttca caaaactatt atcaggagca tttcataggg
     8161 ctaatggtgg ttatttagta ctttatgcag accaattact aaaatataca atgtcttggg
     8221 aaattcttaa aaagactttg cagactaaaa aagtaatatt ggaaacacaa acagcaatta
     8281 aaccagaaaa tatgccattg gatgttaaat tagtactgat tggaagccat tatatatatg
     8341 atattttata tagatatgat gaagattttg aaaaatattt taaagtattt gtagactttg
     8401 atagtgaaat ggataaaaat gaagataatg aagaaggaat agcaagattt atagcatacc
     8461 aatgtgataa gaataattta aggcatttta ctaaatcagc agttgaagag gttattaaat
     8521 ttagcactag attatctggt gatttagaaa aactatcaac taagtttaat aaaataatgg
     8581 aagttgtaat agaaggaagt gcttatgcag agtttagaaa ttcggagtat acagagcagt
     8641 gtgatgttaa aaaagcaata agtgaaaaga gaaaaagaat caatagagtg gaaacacata
     8701 tggatgaatc aattgaaaat ggatttactc taatagaaac agagggaaga aaagtaggag
     8761 tgataaatgg tctgtcagtc ttaagtacag gagaatactc ttttggtaga gcttcaagaa
     8821 ttacagcgac cactagccca ggaagtaaag gcatagtaaa tatagaaaga gaagtaaata
     8881 tgagtggctc tatacataac aaaggagtac ttatattagg tggctatctt tctgagaatt
     8941 ttgcacagga tttactattg tcactaaatg catatgtttg ttttgaacaa aattatggtg
     9001 gaatagatgg agatagcgca tcttctgcag aattatatgt actattatca tctcttagtg
     9061 gagtatcaat taaacaaaat attgctgtta caggttctat aaatcaaaag ggtgatatac
     9121 aagtagttgg tggtataagt gaaaagatag aaggatttta ttctatatgt aaaactaaag
     9181 ggttaaatgg tgagcaagga gtcataattc ctagaaaaaa tcaaagaaat ctcgttttat
     9241 cagatgaagt taatgatgca gtgcgagatg gaaaatttaa gatatatact gttgaaagag
     9301 tagaagaggc tatagagata ttgacagatg ttaaatttga agaaataaag aaattggtaa
     9361 aagaaaaatt aatatctttc agcaagatac aaactgtgtc aaaagaataa gtttattata
     9421 gaatttaatg ggtatttatg tataataaaa agcaagaact ttaataggtt tttgcttttt
     9481 ttgtaaatat atataaatta aattcttatt ttgtatgttt tatatattga tgtttatttt
     9541 ttgttgatat gattaaacta tttataaata gcgttttata aattagtatt ttaaaggggg
     9601 ataattatga aaaatgtaaa tctaaaagag ataaatgaaa aagatgtaat tgtggaagaa
     9661 gatataaatc taaaaggaat ggataagaaa gatgtaattg agaaggaaga agtaaataaa
     9721 aaaagtatag ataagaaaga tataattgag aaagaagaga tagataaaaa aaatgtaaag
     9781 aaggtcgagg ttcaaaaagg aatagataaa atgattggta aaaaagatga gataattgat
     9841 gagaaagata tagagaattt tatggatatt gaagaagata aaaaaagtat caaagtaagt
     9901 aaaaaaagta ctaaaaaagg tgaaacggag aaaaaaacaa agaagagtag ttctaataag
     9961 gctacacaaa aaacaagtaa agaaactaaa agtaagtcta aaattaaaaa tgagtcagca
    10021 aatgaaaaag acgtaaataa gattttagac gagttagaaa aattgtatcc agatgctaaa
    10081 tgtgagttaa attatgggac agcctttgaa cttttaatag caactatttt atcagcacaa
    10141 tgtactgatg taagagtgaa taaagttact tcagagttgt ttaaaaagta caacacagct
    10201 agagactttg ctaatttgag cattgaagaa attagtaaag agataaagag ttgtggtctt
    10261 tacaaaagca agtctcaaaa aataaaggat acatctgaac agctatgtga attatatgat
    10321 ggtgaagtac ctgatagctt agaaaagctt ataaaattac ctggtgttgg aagaaaaaca
    10381 gcaggggttg tacttagtaa cgcttttaat catccagcaa tagctgtaga tactcatgta
    10441 tttagagtta gcaatagaat aggaatagtg gacgagccaa atcctcaaaa aacagaattt
    10501 gcacttatgg aagctatacc aaaagaaaga tggtcacact cacatcatgt attaattttt
    10561 catggaagaa gaatgtgtaa agctagaaat ccagaatgtg caagttgccc aataaaagaa
    10621 gattgtaatt attataaaga acttaatgaa acgaaataac ttttagaaag taagttgtac
    10681 aagagggatt ttctgatata ataatacttg tgaaaatgtt agataaaaaa ctattatata
    10741 catgaaataa aaattattat taacattatt ttatataata gtataatatt attgttattc
    10801 tgtttataaa ataaaatttg ataaataaaa gcgatactta gggaggatta aaatgtcatt
    10861 aaatatagta ttagtagaac cagaaatacc tcaaaataca ggaaatataa taagaacctg
    10921 tgcagcaaca ggttcaactt tacatttagt aaaaccactg ggtttttcat tggatgataa
    10981 acacctaaaa agatgtgggc ttgactattg ggatatagct gatatacaat attacgatag
    11041 ctttgaagaa ttacaagaaa agtatccaaa tagtaaatac tttttttcta caacaaaggc
    11101 taaacagtca cattcagatg tgaaatatga agaaaattgt tttatagtat ttgggaaaga
    11161 aacaaaggga ttaccagaac ctttgttgaa agcaaatatg gatacttgta ttagagtgcc
    11221 tatgttggat gttgaaaaag ctaggtcatt aaatttatca aattcagttg ctattgtagt
    11281 gtacgaggct ttaagacaaa taggataccc aaatatgagg tagtttcaac aagcctaaat
    11341 gagaaaggag catacttaat gaaaaatcta aagataatct gtgacagttt atcggacgtg
    11401 ccaaaagatt tgttagataa atatgatata gatatagttt cattaacagt tatactggag
    11461 gaaagagaat acaaggatag aattgatata tctggagatg aattttataa aaggcttaga
    11521 gaagaaaatg tatatccaaa aacttctcaa gctacttatg cccaatttaa ggaaattttt
    11581 gagaaatata caaatgagga tagagagata ctttatatag cagggtctgc cacagctaca
    11641 ggtacgtatc aaagtgctgt aatggcaaag aatgatgtag atggtaaaat atatacatat
    11701 gactctaact tgctttgtat gggaactggt ttacttgtaa taaaagcagg agaacttgca
    11761 agtgaaggaa agtctgttgc tgaaatattg cctgttttgg atgaattaaa agagaaggct
    11821 tttgttatat tttcagtaga tacattggaa tatttacaaa agggaggtag aatatcatct
    11881 actaaggcag caataggaag tatattaaat ataaaaccga ttcttgaaat aagagatgga
    11941 ttagtttcgc aaatatctca agtaagagga aagaagaatg taatttctaa gatgatggaa
    12001 ttgataaaat caaattgtgg tgatgattta tcagaccaaa ttgtgtatat aggatatagt
    12061 gatgatttta aggaaaagga acaattatct aaggttatgc aagatgaatt aagacctaaa
    12121 gaaattagat ttttccaaat tggtgtgtgt ataggtgcac atgctggtcc tggtgttact
    12181 ggtatcatat gcttaaaaaa taaataatat atttttggat gacattattt atttttttat
    12241 taaattagga tagaatatta attattgaga tgttaaattg gatttatttt ggatgaaatt
    12301 aagtgttgat atattagatt tagtttgtag ggaagtgtgt aaatagataa gaatctattg
    12361 cacacttttt tatagtaaga tttattaaaa aaatttcaaa atgtacttgt aaattgtaca
    12421 taaaaaaatt
//
LOCUS       DAEORM030000088        12337 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.091, whole genome shotgun sequence.
ACCESSION   DAEORM030000088 DAEORM030000000
VERSION     DAEORM030000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12337)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12337)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 12337)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12337
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.091"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            <1..222
                     /locus_tag="KRH23_003488"
     CDS             <1..222
                     /locus_tag="KRH23_003488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HHS5226758.1"
                     /translation="YKGLKEAGIDSEITQYSFCTNGSHYAGEAGIRTIGFGPSKENLA
                     HTIDEYIELDQLFKGAEGYYGILKSVYKK"
     gene            238..1821
                     /locus_tag="KRH23_003489"
     CDS             238..1821
                     /locus_tag="KRH23_003489"
                     /EC_number="3.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047420 - N-acyl-D-amino-acid deacylase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acyl-D-amino-acid deacylase family protein"
                     /protein_id="HHS5226759.1"
                     /translation="MRTLIKHGLIVDGNKTPAYEGDILIENEKILKISQDLNEEADKV
                     IDAKGRVICPGFIDTHSHSDLVILVNPYNEVKIRQGITTEVLGQDGISMAPLPQEHIS
                     SWRKNLAGLDGESDEIDWKYETTENYLKMMDYNGVGLNETYLVPHGNVRMEAMGLEDR
                     PATKEEIQKMCEITERELKAGAIGLSTGLIYIPCAYSLTEEIIEMCKVVAKYDGVFVV
                     HQRSEADTILTSMEEIIEIGKQSGVKVHFSHFKVCGKANWKYIPQVIELLEKAEKEGI
                     RVSFDQYPYAAGSTMLGVVLPPWAHSGGTDKLIERLSDENERAKMKKDIANGIEGWDN
                     FIEFAGIDQIFVTSVKTEKNKDTIGKNLLEIGKMRGKDPLDATFDLLKEEENAVGMVD
                     FYGLEEHIIGFMKRDEQNVCTDGLLAGKPHPRAYGSFPKILGRYVRELNVLTIEEAVY
                     KMTKKAATSFSIKDRGELKEGYFADIVIFDKDTVSGCDDFINSMQYPTGIDYVIINGN
                     CVVEEGKYNKIKAGKVLKN"
     gene            1849..3177
                     /gene="ssnA"
                     /locus_tag="KRH23_003490"
     CDS             1849..3177
                     /gene="ssnA"
                     /locus_tag="KRH23_003490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative aminohydrolase SsnA"
                     /protein_id="HHS5226760.1"
                     /translation="MILVGNGRLISQDSLNPYMEDGCVVINDNLIEDIGTTEEMKAKY
                     PVHEFIDAGKKIIMPGLINSHMHIYSSFARGMAVPGKPSENFLEILNNLWWRLDKQLT
                     LEDTKYSAYATYIECIKNGVTTVYDHHASPNAIEGSLFTISDVAKDLGIRTCLCYEVS
                     DRDGGNTIQQGINENVNFIKYAQKDDTDMIKGMFGLHAAFTLSDDTLNKCASEMAGLD
                     TGYHVHVAEGLADLQYNVDKYGKRVLERFNDFGVLKEKTIAVHCIYISAEEISLLNKT
                     NTFVVHNPESNMGNAVGCSPAIELLKRGVTVGLGTDGYTSDMFESLKVANIIHKHHLK
                     DPRVGFEESQTMLFDNNRKIAKAYYKNDLGVLKKGAYADVIVVDYIPHTPLTENTIGG
                     HTIFGMSGRSVDTTIINGKVLMKDRKLINIDEESILAKSRELSQNLWNRI"
     gene            3376..4728
                     /locus_tag="KRH23_003491"
     CDS             3376..4728
                     /locus_tag="KRH23_003491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015851 - nucleobase transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleobase:cation symporter-2 family protein"
                     /protein_id="HHS5226761.1"
                     /translation="MSRDKSPKIAPVDERLPVSKSWVFSLQHVLAMCAGAVAVPMMIG
                     SAARLDHASIVFLINACLFMAGIGTLIQSVGIGNIVGAKIPVIEGTSFAAVAGMTAIA
                     SSYSDSQVAIQTVFGSVIVAGLFCILLAPVFEKLIRFFPSVVTGTVVMVIGISLFPVG
                     IKWITDNKLEAVEPNSLALALAVLAITLLSFKFLKGIWNSTAILVGIVLGTLLSMAVG
                     MADFSAVNGVGWLNLNVPLKFGMPRFEPSAILSLCLIMLVLMTESVGNMIAIHEMVDK
                     EVTGKNIKRGLFGDGISTALSGIFNSFPITPFGQNTGIVGLTGIKSRFIAVYAGVILL
                     VLGFLPKFAAIIGAIPKPVLGGVGFAMFGMVMVGGVKTLSKVKFDGTKNGVIVAVSVG
                     LSMIPLTNPDFYHNFPTWVQTIFHSGITTGSLSAVLLNIFFNELGSKKEKNNKVEEAK
                     "
     gene            4920..6029
                     /locus_tag="KRH23_003492"
     CDS             4920..6029
                     /locus_tag="KRH23_003492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HHS5226762.1"
                     /translation="MANLKVNLYGMEFLNPIMTAAGPGAKDGALCQEAAKGGAGAICT
                     KTISVLPADVPRPCMAKTNSGFLNTELWSELPKEQWIEEEYKKVKETGLPVIVSMGYS
                     AEQIAEVAPLVKPYADAVELSTHYVGTDVAPIVNALKAAKAVLDVPVFMKMSPHTDIQ
                     TIAKAVEEAGADGLVMINSFGPCMAIDVNTGYPIMGSKAGYGWLSGAPIRPLAIRCIY
                     EASQVVNIPIIGVGGITCGKDVAEMMMAGASAVQVCTEAILKGPSIYGKIAKELNEFL
                     DENGYADVNEIKGLTHKKMAARGFRTHSVAPVVDDNKCIKCKQCVTSCVYEALEVTDK
                     LNIDADKCFGCGLCVTRCPKGALSICYNQVEAMNE"
     gene            6312..7703
                     /gene="hydA"
                     /locus_tag="KRH23_003493"
     CDS             6312..7703
                     /gene="hydA"
                     /locus_tag="KRH23_003493"
                     /EC_number="3.5.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004157 - dihydropyrimidinase activity
                     [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropyrimidinase"
                     /protein_id="HHS5226763.1"
                     /translation="MGIVLKGGKVVTSEKTYCADVRIEDEKIVDIGLDISKENDEIVD
                     VSDSYVIPGGIDTHTHFDLDTGVTKTADNFETGTKAAIVGGTTTILDFATQAKGCSLK
                     DGLEEWHEKAKDKSYSDYGFHMAITDWNDSVCNEMEDMVKEGVSSFKLYMAYKGSLQV
                     DDGVIFEALRKAEEIGGIIGFHCENGDIICELVDKAKSENNLSPKYHQLTRPAIMEAE
                     ATSRLMKIAEVANSKVYVVHLSCKESLEEVLKAKQRGVDVIVETCPQYLLLNDELYDL
                     DGFESAKYVMSPPLRNKENNEILWNAILDNQIDTIGTDHCSFNYKGQKELGINDFSKI
                     PNGSPGVEHRMSLLYTYGVCKNKISINKMVEVTSTNAAKLFGMYPNKGTIEIGSDADI
                     LVLNPNKKSKIEAKKQLQNVDYTPYEGYEVDCQIEHVYLRGKEVVRDGELICNTPSGR
                     YINRRLTKGAREW"
     gene            7697..10258
                     /gene="xdh"
                     /locus_tag="KRH23_003494"
     CDS             7697..10258
                     /gene="xdh"
                     /locus_tag="KRH23_003494"
                     /EC_number="1.17.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004854 - xanthine dehydrogenase activity
                     [Evidence IEA];
                     GO_function: GO:0043546 - molybdopterin cofactor binding
                     [Evidence IEA];
                     GO_process: GO:0046415 - urate metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="selenium-dependent xanthine dehydrogenase"
                     /protein_id="HHS5226764.1"
                     /translation="MVEFILNGEKVVAKEGKKLLDFLREDMNITSVKNGCSEGACGTC
                     MVIIDGKATKACVFKTDKLAGKNITTIEGLSERERDVFAYSFASQGAVQCGFCIPGMV
                     ISSKALIDVNNNPTEDDIKKALKGNICRCTGYVKIIKAVDLAAKIFRENIDVPKVNCK
                     GLVGENLPRVDAVGKALGYSEYVDDMRIEGMIYGSAVRAKYPRALVKKIDIEEAKAYP
                     GVVAVLTAKDIPGTIKVGHLKKDWDTLIPEGEITRYLGDGIVLVAAETREALEEAKKL
                     VKIDYEELTPLSTTADALREDAPKIHETGNILVKEHLVRGNAKEKIENSKYVVTKRYT
                     TPATEHAFLEPECAVAGPYEDDGVIIYSTDQGVFATQHECADMLGLPYEKVRVINKMV
                     GGGFGGKEDMSVQHHAALLAYHTKRFVKVQLTRKESIIVHPKRHATEMEFTTACDENG
                     YLTGMKATIISDTGAYASLGGPVLQRLCTHAAGPYNYQDIDITGTAVYTNNPPGGAFR
                     GFGVTQSCFATECNLNLLAEMVGISPWEIRYKNAIRPGQVLPNGQFADEGTAMAETLE
                     AVKEEYEKHPRAGIACAMKNSGVGVGIPDVGRCRLVIKDGKVHIRTSASCIGQGLGTV
                     MTQVVCETASLLPENIVHEVPDTHLTPDSGNTTASRQTVFTGEATKVASNKLKEALDS
                     GKTLLDLEGEEFYGEYESITDKMGCDKENPVSHVAYGYATQVVILDENGKLEKVVAAH
                     DVGRAINPISLEGQIEGGVVMGLGYALTEDYPVVNSVPTAKFGTLGLFKSTDIPEIQA
                     LIVEKNKDLLAYGAKGVGEICTVPTAPAVQNAYYVFDKEFRTELPLQNTPYSKKK"
     gene            10410..11756
                     /gene="rpoN"
                     /locus_tag="KRH23_003495"
     CDS             10410..11756
                     /gene="rpoN"
                     /locus_tag="KRH23_003495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HHS5226765.1"
                     /translation="MNFNNSLELTQSQKLIMTTQLKQSLSILNMSKLELEEEIKREAE
                     NNPLVEVEKSGEINWEEYIKDMDRSRRLDRTEISYNPDNEVNLENLVKYSSNLYEDLK
                     FQISLYKLTDKELEVCEYIIDSLDEDGYLRTEEKVIVDTLKIDEELFEKCLISVQQLE
                     PSGVGARSLSECLMIQMASLGIYNEILEEIVTKDLNLIANNKYKEISKKYNMSLQKCV
                     ELINIIKTLDPKPGRTCSVEKSVYIQPDVTVEKIDDEFIVYLNEKDSYQIRINSYYKD
                     ILKNSQSDESAKEFIKERLNSATGLMKNIESRKTTVLKIAEEIVKAQDEFLRKGTKYI
                     KPLKMKDIAEKLEFHESTISRGVNGKYMLTPFGVYEFRYFFSSAIETENNEMASSTSI
                     KKIIKETIKDENKKKPLSDDHISKLLKEKGINVARRTVAKYREELGIPSSSKRKEY"
BASE COUNT         4949 a         1422 c         2487 g         3479 t
ORIGIN      
        1 tataagggat taaaagaagc tggaatagat tcagaaataa ctcaatactc attctgtacg
       61 aatggaagtc actacgcagg tgaggctgga ataagaacta taggatttgg tccttctaag
      121 gaaaatcttg ctcatacaat agatgagtat atagaattag accaattatt caaaggtgca
      181 gaaggatatt atggtatatt aaaatcagtt tataaaaaat aattaggaga tggttttatg
      241 agaactttaa taaaacatgg gcttatagta gatggaaata aaacaccagc atatgaagga
      301 gatattttaa tagaaaacga gaaaatatta aaaatatcac aagatttaaa cgaagaagct
      361 gacaaagtta tagatgcaaa aggtagagtt atatgtccag gtttcataga tactcatagc
      421 cattcagacc tagttatttt agttaatcca tataatgagg taaagattag acagggaatt
      481 acaacagaag tgttgggcca agatggtata tctatggccc ctctacctca agagcatata
      541 tcttcttgga gaaaaaattt agcaggttta gatggtgaaa gtgatgaaat tgattggaaa
      601 tatgaaacaa cagagaatta tttaaaaatg atggattaca atggggtagg tttaaatgaa
      661 acttatttag tacctcatgg aaacgttaga atggaagcta tgggacttga agatagacct
      721 gctactaaag aagaaattca aaaaatgtgt gaaatcacag agagagaatt aaaagcagga
      781 gctataggat tgtctactgg acttatatat ataccttgtg catactcatt gactgaagaa
      841 attatagaga tgtgtaaggt agtagcaaaa tatgatggag tatttgtagt tcaccaaaga
      901 agtgaagcag atacaatttt aacttcaatg gaagaaatca tagaaattgg aaaacaatca
      961 ggagtaaaag ttcatttttc acattttaag gtttgtggta aagcaaactg gaagtatata
     1021 ccacaagtta tagagctttt agaaaaagca gaaaaggaag gaataagagt atcttttgac
     1081 caatatccat atgcagcagg aagtacaatg cttggagtag ttttacctcc ttgggcacat
     1141 tctggaggaa ctgataagtt aatagaaaga ttaagtgatg aaaacgaaag agcaaaaatg
     1201 aaaaaagata tagcaaatgg aatagaaggc tgggataatt ttatagaatt tgctggaata
     1261 gaccaaatat ttgtaacaag cgtaaaaaca gaaaagaata aagatacaat tggtaagaac
     1321 ttattagaaa ttggaaaaat gagaggaaaa gacccattag atgcaacgtt tgatttatta
     1381 aaagaagaag aaaatgcagt tgggatggta gatttctatg gattagaaga acatataata
     1441 ggattcatga aaagagacga gcaaaatgtg tgtacagatg gtcttttagc aggtaaacca
     1501 catccaagag cttatggttc tttccctaaa atactaggaa gatatgttag agagttgaat
     1561 gtgttaacaa tcgaagaagc tgtttataaa atgactaaaa aggcagctac aagctttagt
     1621 ataaaagata gaggcgaatt aaaagaagga tattttgcag atatagttat atttgacaag
     1681 gatacagtta gtggttgtga tgattttatc aactctatgc agtaccctac aggtatagat
     1741 tacgtaatta taaatggaaa ttgtgttgtt gaagaaggaa aatacaataa aattaaagca
     1801 ggaaaagtac ttaaaaatta aatcttagct ttaaggagga ataaatttat gattttagtg
     1861 gggaatggga ggctaataag ccaagattct ttaaatccct atatggaaga tggatgtgta
     1921 gtaataaatg ataatctaat tgaagatata ggtactacag aagaaatgaa agctaaatat
     1981 ccagtacatg aatttataga tgcaggcaag aaaataatca tgccaggtct aataaattca
     2041 catatgcata tatacagctc atttgctaga ggaatggcag ttccaggaaa accttctgag
     2101 aactttttag agatactaaa caatttatgg tggagacttg acaaacagct tacactggaa
     2161 gatacaaaat acagtgcata tgcaacgtat atagaatgta taaaaaatgg tgtaacaaca
     2221 gtttatgacc atcatgcaag tccaaatgca attgaaggca gtttgtttac aatatcagat
     2281 gttgcaaagg atttgggaat tagaacgtgt ctttgttatg aagtgtctga tagagatggt
     2341 ggaaatacaa tccaacaagg tatcaatgaa aacgtaaact ttataaaata cgctcaaaaa
     2401 gatgatacag acatgataaa aggaatgttt gggcttcatg ctgcatttac actatctgat
     2461 gatacattaa ataaatgtgc ttcagagatg gctggtcttg atacaggtta ccatgtacat
     2521 gttgctgaag gactagcaga cttacaatat aatgtagata aatatggaaa aagggtttta
     2581 gaaagattca atgattttgg agtactaaaa gaaaaaacaa tagcagttca ttgtatatat
     2641 ataagtgcag aagaaatcag tcttttaaat aaaacaaata catttgtagt tcataatcca
     2701 gaatctaata tgggaaatgc agttggatgt tctcctgcaa tagagttatt aaaaagggga
     2761 gttacagtag gattaggaac tgatggatat actagcgata tgtttgaatc attaaaagtt
     2821 gccaatataa ttcacaaaca tcacttaaaa gacccaagag ttggatttga agaatcacaa
     2881 acaatgttat ttgataacaa tagaaaaata gctaaagctt attataaaaa tgacctagga
     2941 gtacttaaaa aaggtgctta tgcagatgtt atagtagttg attatatacc acatactcca
     3001 ttgacagaaa atacaatagg gggacacact atttttggaa tgagtggaag aagcgtagat
     3061 acaactatta taaatggaaa agtacttatg aaagatagaa agttaataaa catagatgaa
     3121 gaaagtattc tagcaaaaag tagagaatta agtcaaaatc tatggaatag aatttaaata
     3181 attgattatg caaaattcta tgaagcagga accctgtgac tttagtcatg ggaggttcag
     3241 attaatatac aagtaagaaa caagaattta gatattaaaa acagagctta aacaaaaata
     3301 ggaatttaaa tgaagtatat aaataaaaaa tatacggaat agaatattaa attaaatata
     3361 gaagggagac ccaaaatgtc tcgagataaa agccctaaaa tagctccagt agatgaaagg
     3421 ttacctgtat ccaaatcttg ggtattttca ctacagcacg ttttagcaat gtgtgcagga
     3481 gcagtagcag ttcctatgat gataggaagt gctgcacgac tagatcatgc tagtattgtt
     3541 tttttaataa atgcttgctt gtttatggca ggtataggaa cactcataca aagtgttggt
     3601 ataggaaata ttgtaggtgc taaaatacca gtaatagaag gaactagttt tgccgctgtg
     3661 gcaggtatga cagcaatagc ctcatcatat agtgattcac aagttgcaat acagacagta
     3721 tttggctctg taatagtagc tggattgttt tgtatattac ttgctccagt atttgaaaaa
     3781 ttaataagat ttttccctag tgtagttact ggaacagttg ttatggtaat aggtatttca
     3841 ctatttccag ttgggataaa atggataact gacaacaaat tggaagcggt tgaaccaaac
     3901 tcattagcat tagctttagc agtattggca ataactttac tttcatttaa attcttaaaa
     3961 ggaatttgga atagcacagc tatattggta ggtatagtac ttggtacact actttccatg
     4021 gcagttggaa tggcagattt tagtgcagta aatggagttg gttggcttaa cttaaatgta
     4081 cctttaaaat ttggaatgcc tagatttgaa ccatctgcaa tactatcatt gtgtttgatt
     4141 atgttggtac ttatgacaga atcagttggt aatatgatag ctattcatga aatggtagac
     4201 aaagaagtaa caggtaaaaa tattaaaaga ggtctatttg gagatggaat atctacagca
     4261 ttatctggaa tattcaattc atttccaata actccatttg gtcaaaatac aggaatagta
     4321 ggtcttacag gtataaaatc aagatttata gcagtttacg caggggttat attgctagta
     4381 cttggattct taccaaaatt tgcagcaata ataggagcaa tacctaagcc tgttcttgga
     4441 ggcgtaggat ttgcaatgtt tggaatggta atggttggag gagtaaaaac tttaagcaaa
     4501 gtgaaatttg atggaactaa aaatggggtt atagtagcag ttagtgttgg tttgtctatg
     4561 ataccactaa caaatcctga tttctatcat aatttcccaa cttgggtaca aacaatattc
     4621 catagtggaa taacaacagg tagtttatca gcagtgcttt taaacatatt cttcaatgaa
     4681 ctaggttcta aaaaagaaaa aaataataaa gttgaagaag caaaataaaa ataaaacaag
     4741 taaaaatcta tattgactta aagtcattaa gtattaataa aaataattca gagatattaa
     4801 taattcaaca aaactatctt atattttaaa taatataaaa aagtaaataa ataacgaata
     4861 caaataaaag aatacaatct aaatattaaa aatatttaat ttaagggaga gataataata
     4921 tggctaattt aaaagttaat ttatatggaa tggaattttt aaacccaatt atgacagcgg
     4981 caggacctgg agcaaaagat ggtgctctct gtcaagaggc agcaaaaggt ggagcaggag
     5041 ctatatgtac aaaaactata tctgtattac cagctgatgt accaagacca tgtatggcaa
     5101 aaactaatag tggtttttta aacacagaat tatggtcaga gcttccaaaa gagcaatgga
     5161 tagaggaaga atacaaaaag gtaaaagaaa cagggcttcc agtaatagta agtatgggat
     5221 attcagcaga gcaaatagct gaggttgctc ctttagtaaa gccttatgca gatgcagttg
     5281 aattatctac tcattatgta ggtacagacg ttgcaccaat agtaaatgct ttaaaagctg
     5341 caaaagctgt tttagatgta ccagtattta tgaaaatgag tcctcatact gacattcaaa
     5401 ctattgcaaa agctgttgaa gaagcaggtg cagatggact tgtaatgata aactcatttg
     5461 gaccatgtat ggcaatagat gtaaatacag gataccctat aatgggaagt aaagctggat
     5521 acggatggtt atcaggtgca ccaataagac ctctagcaat aagatgtata tatgaagctt
     5581 ctcaagttgt aaatatacca ataatcggtg ttggtggaat cacttgtgga aaagacgtgg
     5641 ctgaaatgat gatggctgga gcaagtgctg ttcaagtatg tacagaagca atccttaaag
     5701 ggccttctat ctatggaaaa attgctaaag aattaaatga atttttagat gagaatggat
     5761 atgctgatgt taatgaaata aaaggattaa ctcataagaa aatggcagct agagggttta
     5821 gaactcattc agtagctcca gtagtggatg ataacaagtg tatcaaatgt aagcaatgtg
     5881 taacaagctg tgtatacgaa gctttagaag ttacagataa gttgaacata gatgcagaca
     5941 agtgttttgg atgtggatta tgtgtaacta gatgtccaaa aggagcttta agcatctgct
     6001 acaatcaagt agaagctatg aatgagtaat aattatatag aattttggta attaacttag
     6061 agtaataggt attaggataa taaaatatat cagataaaca aacacacatt atgcattaat
     6121 aatacagtct aaagttaata attttattat attgatttaa ctaaatatta gtttagctga
     6181 atattaattt aattaggtat tggtttaatc ttaatataga tttactacgt ataagtgaac
     6241 taactagatt actttaagtt aattttttca tataaaataa attgatacat tacaagtaag
     6301 gtggagtcta tatgggaatt gttttaaaag gtgggaaagt agtaacaagt gaaaaaactt
     6361 actgtgcaga tgtaagaata gaagatgaaa aaatagtcga tataggtctt gatatatcaa
     6421 aagaaaatga tgaaatagtt gatgttagtg attcttatgt tataccagga ggtatagata
     6481 cacacacaca ctttgactta gatacaggcg ttactaagac agcagataac tttgagacag
     6541 gaacaaaagc tgctatagta ggaggaacta ctactatatt ggattttgct acacaagcta
     6601 aaggatgttc tttgaaagac ggattagaag aatggcatga aaaagctaag gataaatcct
     6661 attcagatta tggctttcat atggctataa cagattggaa tgactcggtt tgtaatgaaa
     6721 tggaggatat ggtgaaagag ggagtatctt catttaaact gtatatggcg tataaaggaa
     6781 gccttcaagt tgatgatggt gtaatctttg aagcattgag aaaagcagaa gagataggag
     6841 ggattattgg tttccattgt gaaaatgggg acataatatg tgaacttgtg gataaagcaa
     6901 agtcagaaaa taatttatct ccaaaatatc atcaattaac tagaccagct ataatggagg
     6961 cagaagctac atcaagactt atgaagatag ctgaagttgc aaactctaaa gtatatgtag
     7021 ttcacttaag ctgtaaagaa tccttagagg aggttttaaa agctaagcaa agaggtgtgg
     7081 atgtaatagt tgaaacttgt cctcaatacc ttctattaaa tgatgaatta tatgatttag
     7141 atggatttga aagtgctaag tatgtaatgt caccaccttt aagaaataaa gaaaataatg
     7201 aaatattatg gaatgctatt ttagataatc aaatagacac tataggaaca gaccattgtt
     7261 cttttaatta taagggacag aaggaacttg ggataaacga tttcagcaag ataccaaatg
     7321 gttctccagg tgtagaacat aggatgagtc ttttatacac atatggagtc tgtaaaaata
     7381 aaatatctat caacaagatg gtagaagtaa catcaactaa tgcagcaaag ttgtttggaa
     7441 tgtatcctaa taaaggaact atagaaatag gcagtgatgc agatatatta gtcttaaatc
     7501 caaacaaaaa atccaaaata gaagcaaaaa aacaattaca aaatgtagat tatacacctt
     7561 atgaagggta tgaagtggat tgtcaaatag aacatgttta tttaagagga aaagaagtag
     7621 ttagagatgg agaattaatt tgtaatactc caagtgggag atatataaat aggcgtctaa
     7681 caaagggggc tagagaatgg tagaatttat attaaatgga gagaaagttg ttgcaaaaga
     7741 aggcaaaaaa cttttagact tccttagaga agatatgaat ataacttcag ttaaaaatgg
     7801 atgttcagaa ggtgcttgtg gaacatgtat ggttataata gatggtaaag ctactaaagc
     7861 atgtgtattt aaaactgata aattagctgg gaaaaacata acaactatag agggattatc
     7921 agagagagaa agagatgttt ttgcatattc ttttgctagt caaggagctg tacaatgtgg
     7981 attttgtatt ccaggtatgg taattagttc aaaagcactt atagacgtta ataataatcc
     8041 tactgaagat gatataaaga aagctttaaa aggcaatata tgtagatgta cagggtatgt
     8101 aaaaataatt aaagctgtcg atttagcggc aaagattttt agagaaaata tagatgtgcc
     8161 aaaagtaaac tgtaagggtt tagtaggtga aaatcttcct agagttgatg cagttggcaa
     8221 agcacttgga tattctgaat atgtagatga tatgagaatt gagggtatga tttatggttc
     8281 agcagttaga gctaagtatc ctagagcttt agttaaaaaa atagatatag aagaagcaaa
     8341 agcttatcca ggagttgttg cagttctaac agctaaagat attccaggaa ctataaaggt
     8401 aggacactta aagaaggatt gggatacttt aataccagaa ggtgaaataa ctagatactt
     8461 aggagatgga atagttttag tagcagcaga aactagagaa gcgttagaag aggccaaaaa
     8521 gctagttaag atagattatg aggaattaac accattaagt actacagcag atgcacttag
     8581 agaagatgct ccaaagatac atgagacagg gaatatactt gttaaggaac atttagtaag
     8641 aggaaacgct aaagaaaaga tagaaaattc aaaatatgtt gtaactaaaa gatatactac
     8701 acctgctaca gaacacgcat ttttagagcc tgaatgtgca gtagctggtc cttatgaaga
     8761 tgatggagta ataatctatt caacagacca aggggtgttt gccactcaac atgaatgtgc
     8821 agatatgtta gggttaccat atgagaaggt aagagttata aacaaaatgg taggaggagg
     8881 gtttggtgga aaagaagaca tgagtgttca acaccatgca gccttacttg cataccatac
     8941 aaagagattt gtaaaagtac agttaacaag aaaagaaagt attattgttc atccaaaacg
     9001 acatgccaca gaaatggaat ttacgacagc atgtgatgaa aatggatact taacgggtat
     9061 gaaggcaacg ataatatctg acacaggtgc atatgcctct cttggaggac cagtgctaca
     9121 aagactgtgt actcatgcag caggaccata caattatcaa gatattgata taacaggaac
     9181 agcagtatat actaataacc ctcctggagg agcatttaga ggatttggag ttacacagag
     9241 ttgttttgca actgaatgta atctaaattt acttgctgaa atggttggaa tatctccttg
     9301 ggagataaga tataaaaatg caataagacc tgggcaagtt ttaccaaatg gtcaatttgc
     9361 agatgaagga acagcaatgg cagagacact agaagctgta aaagaagagt atgaaaagca
     9421 tccacgtgca ggtatagctt gtgctatgaa aaatagtggg gttggagttg gtatacctga
     9481 tgttggaaga tgtagattgg tgataaaaga tggcaaagtt cacataagaa caagtgcttc
     9541 ttgtataggt caagggcttg gtactgttat gactcaagta gtttgtgaaa ctgctagcct
     9601 acttcctgaa aatatagtgc atgaagttcc agatactcat ttaacaccag actctggtaa
     9661 tactacggct tcaagacaga cagtatttac gggagaagct actaaggttg catcaaataa
     9721 gttaaaagaa gctttagact ctggcaaaac tttacttgat ttagagggag aagagtttta
     9781 tggagaatat gaaagtatta cagataaaat gggttgtgac aaagaaaatc cagtaagtca
     9841 tgttgcttat ggatatgcaa cacaagttgt aattctggat gaaaatggaa aactagaaaa
     9901 agtagtagca gcacatgatg ttggaagagc tataaatcca atcagtttag aaggtcaaat
     9961 agaaggtgga gtagttatgg gtcttggata tgctctaacc gaagattacc cagtagtcaa
    10021 ctctgttcct acagctaagt ttggtacatt aggtttattt aaatctacag atataccaga
    10081 aatacaagct ttaatagttg aaaagaacaa agatttattg gcttatgggg caaaaggtgt
    10141 aggagaaatt tgtacagttc ctactgcacc agcagtacaa aatgcctatt atgtatttga
    10201 taaagaattt agaactgagc taccactaca aaatactcca tatagtaaaa aaaagtaaca
    10261 aaaaaaagaa atattaaata aaaaaataga tgaaattgta aataaaaaaa acccttttgc
    10321 ataaggtata ttttaaatga tagaatatac atatacagga gggtttttct tttataaaat
    10381 aagtttaata aaattgagag gtgagcagaa tgaattttaa taatagtcta gaattaactc
    10441 agtctcagaa gctaataatg actacacaac ttaagcaatc attatcaata ttaaatatga
    10501 gtaagttaga gttagaagaa gagataaaaa gagaagcaga gaataaccca ttagttgaag
    10561 tcgagaaaag tggggagata aattgggaag agtatataaa agacatggat aggtcaagac
    10621 gtttagatag aacagagata agctataatc ctgataatga agttaatcta gaaaatttag
    10681 ttaaatattc gtcaaattta tatgaagatt taaaatttca gataagcctg tataaactta
    10741 cagacaaaga attggaagtc tgtgagtata taattgatag tttagatgag gatggatatt
    10801 taagaactga ggaaaaagta attgttgata ccttaaagat agatgaagaa ctttttgaaa
    10861 aatgtttaat tagtgttcag cagttggaac ctagtggagt aggggcaaga agtctttcag
    10921 aatgtctgat gatacaaatg gctagtttag gaatatataa tgaaatttta gaggaaatcg
    10981 ttacaaaaga cttaaattta attgcaaata ataaatacaa agagataagt aaaaagtaca
    11041 atatgtcatt acaaaaatgt gttgaactaa taaacataat taagacatta gaccccaaac
    11101 caggaagaac ttgttcagta gagaaaagtg tatacattca acctgatgta acagtagaaa
    11161 aaattgatga tgaatttatt gtatatttaa atgagaaaga ttcttatcaa ataagaatca
    11221 atagttatta taaagacata ttaaaaaatt cacagtctga tgaaagtgca aaagaattta
    11281 taaaagaaag actaaattca gcaacaggac ttatgaaaaa tatagagagt aggaaaacta
    11341 cagtacttaa gattgcagaa gagatagtaa aagctcaaga tgaatttttg agaaaaggga
    11401 caaaatatat aaaacctttg aaaatgaaag acatagcaga aaaattagaa tttcatgaat
    11461 ctactataag tagaggtgta aatggtaaat atatgctaac accttttggc gtatatgaat
    11521 ttaggtactt tttcagtagc gccattgaga ctgagaataa tgaaatggca tctagtacaa
    11581 gcataaaaaa aattataaag gaaacaataa aagacgaaaa taaaaagaaa cctttaagtg
    11641 atgaccatat atctaagtta ctaaaagaaa aaggaatcaa tgttgcaaga aggacagttg
    11701 ccaaatatcg tgaagaatta ggaatcccat cttcaagtaa gagaaaagaa tactaataag
    11761 taaaagacaa atatcagtat ggtaagggga aaaggctaat taagagatga atgtagattg
    11821 ggctaaaaat tttataaagt aaaataatag aatatggaaa agtattaaaa tgctataagg
    11881 tattaaaaaa ctggggaaca ttaaaacatt aagatagcaa agaacataaa aaactaaaga
    11941 agattaaaac attaaagaac attagagctt tgaggaatat tagaacttta aagaatatta
    12001 aaatttataa aatataaaaa tactaaaaag aattgaaaaa ctggggaaca ttaaaatatt
    12061 gtaaaatgct aaaaaactag aaaacataat taaataagtg cttataaaga atgattaaat
    12121 taaataagtg tttgtaaaga ataattagat attagaaaaa gaagaatacc tagataaata
    12181 aactattatt aaatttaata atcacaaaag gaaaacacgt agggtataaa taaaaatctt
    12241 aactagataa aagtaaactt agttgtagat aaaaataact agaaataaaa gtaactagaa
    12301 ataaaattat ttatagtaat aaatattaga atgaaaa
//
LOCUS       DAEORM030000089        12279 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.092, whole genome shotgun sequence.
ACCESSION   DAEORM030000089 DAEORM030000000
VERSION     DAEORM030000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12279)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12279)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 12279)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12279
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.092"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            <1..237
                     /locus_tag="KRH23_003496"
     CDS             <1..237
                     /locus_tag="KRH23_003496"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226766.1"
                     /translation="IMAQVRKLNRILTIEECKIDDFLEMGYDLIDETGKVVRYGKSLN
                     VKDLIAENNILRSKVESLEEENKQLKEKNKLTKK"
     gene            247..648
                     /locus_tag="KRH23_003497"
     CDS             247..648
                     /locus_tag="KRH23_003497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226767.1"
                     /translation="MGNNIIDDIEKRLESFGYILKDGDKWLIDFVREKIENIIKLDCN
                     IKTMPIELKEIEADMIVGEFLFTKKNMGQLDIESINFEAVEKSISEGDTKVDFAIGSG
                     SQTPEQRFDSLIAYLTAYGKNKILTFRCLRW"
     gene            642..989
                     /locus_tag="KRH23_003498"
     CDS             642..989
                     /locus_tag="KRH23_003498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226768.1"
                     /translation="MVSKTRKAIEMLYRYKCTIVEYQPIKDPVTKRTNNKEVIVLENQ
                     PCKLSYKNIVSATEGKLAKLEQTIKLFISPDIEIKAGSKLIINDKEYVRSGESAIYPN
                     HQEIILELFKDKA"
     gene            989..1414
                     /locus_tag="KRH23_003499"
     CDS             989..1414
                     /locus_tag="KRH23_003499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HHS5226769.1"
                     /translation="MARWGSVDFREFKRVCKKMEKLTKIDLDKFCKDAARELAARLLG
                     KVIRRTPVDTGFLRQGWNGVAYARSLPVYKQGNNYIIEVVNPTEYASYVNFGHRTKDG
                     KGWVKGQHFLTISEMELQSQVDKIIEKKLLILLKGVFDA"
     gene            1407..1844
                     /locus_tag="KRH23_003500"
     CDS             1407..1844
                     /locus_tag="KRH23_003500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail terminator family protein"
                     /protein_id="HHS5226770.1"
                     /translation="MLNNIIDGISVKLDKSFGEKYTIYSEDVEQGINEPCFFIVPLNP
                     SKTPYPSGRELKKNSFDVHYFPRSEAKNFEINEIAEMLLEELEYIEINGDLVRGTNMN
                     FEIIDNVLHFFVDYNYFTIKSNNADKMNTVELFGGLKRGDNFE"
     gene            1828..2013
                     /locus_tag="KRH23_003501"
     CDS             1828..2013
                     /locus_tag="KRH23_003501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226771.1"
                     /translation="MIILSKTLSKGTDYKFTKEQIVNSKKYVNRKDLLNAILKENELY
                     SFSEVEDRINKFMKGVS"
     gene            2014..3324
                     /locus_tag="KRH23_003502"
     CDS             2014..3324
                     /locus_tag="KRH23_003502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail sheath family protein"
                     /protein_id="HHS5226772.1"
                     /translation="MALGGGTFVTQNKVLPGSYINFVSATRATSSLSDRGIVAMPLEL
                     DWGIDEEVFQVTSDDFEKYSTKYFGYDYTHEKLKGLRDLFKNIRLGYFYKLNKGVKAS
                     CSIATARCSGIRGNDLKVIVTTNIDDNAKFDVVTLLDNKKVDTQIAKVITELQDNDYV
                     TWKKEATLEATAGLTFTNGTNGEAVTGTEYQAFLDKIESYSFNALGCLATTAEIKSLF
                     VEFTKRMRDKVGAKFQTVLYKKNDADYEGVVSVENKIKDTGLLESSLIYWTTGAIAGC
                     DINKSNTNKRYDGEFDVDVNYTQIHLEEALKTGKFIFHKVGDEVHVLEDINTFVSFTD
                     EKNDDFSSNQSVRVLDQIANDIATLFNTKYLGEVPNDKSGRISFWNDVVKHHEQLQNM
                     RAIEDFKADDVSVEPGSDKKTVVVSDAVKVISAMSKLYMTVSVS"
     gene            3346..3816
                     /locus_tag="KRH23_003503"
     CDS             3346..3816
                     /locus_tag="KRH23_003503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tube protein"
                     /protein_id="HHS5226773.1"
                     /translation="MAQQIKARDTISASKAECFVTIKGKRYNFMQAINLEAKMEKNKS
                     EIPILGSTTKGNKSTGSKYSGNATFYYNTSIFRELLYEYKETGEDIYFDIQITNEDPT
                     SSVGRQTIILEDCNMDSGIIAKFDADGEYLDEDMDFTFENWKLVEKFNIANGME"
     gene            3869..4126
                     /locus_tag="KRH23_003504"
     CDS             3869..4126
                     /locus_tag="KRH23_003504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226774.1"
                     /translation="MIKIKDKYEIKDSISFDYSNKRPLEERVSEMYKKAGKYLIDISD
                     KLATDTIDGSSLKPIIIKFEINEAGVATIEKQTKYLVMEVE"
     gene            4131..4571
                     /locus_tag="KRH23_003505"
     CDS             4131..4571
                     /locus_tag="KRH23_003505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail assembly chaperone"
                     /protein_id="HHS5226775.1"
                     /translation="MGDLNAFLSQNAIKVENRKYVASERFIGEDGKAIEWELKAIDSD
                     RDRQLRKDSTIRVPVLNKKGKATGQYTSETDFNTYTLKLCVETVVFPDLHDAELQNSY
                     GVMGAEELLTTMLTPGEYTDLSSEVGEVNGFDRTFEDKVEEAKN"
     gene            4892..5053
                     /locus_tag="KRH23_003506"
     CDS             4892..5053
                     /locus_tag="KRH23_003506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA];
                     GO_function: GO:0090729 - toxin activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin"
                     /protein_id="HHS5226776.1"
                     /translation="MDNFLLSILASLIASLIGYIVCRCIKNVKSHSTRGKSKSGWELG
                     FKIKFRKFK"
     gene            5202..5435
                     /locus_tag="KRH23_003507"
     CDS             5202..5435
                     /locus_tag="KRH23_003507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226777.1"
                     /translation="MNKDIELTEKDLYCIARHIQVYVFKKDDEVIKKEDNPCCRCKHK
                     FKYYENSVCIYHCSVFQKLSKITGLKMGFGVKL"
     gene            5495..6022
                     /locus_tag="KRH23_003508"
     CDS             5495..6022
                     /locus_tag="KRH23_003508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4352 domain-containing protein"
                     /protein_id="HHS5226778.1"
                     /translation="MREGKRRRGCLFWFIIIIIFSGVVGAIAGNSTNNGSTEKQKEDL
                     TKYIGEEGNIGDLKLTVNSISKASEIPVASGYLAYTPDSGKYGIINLTIKNQTKESQS
                     FMLNSFTLIGPDNSKYVPSLLIDVGNKYITMDTVNPNLDVTGNIAFEIPKDLLVSDCK
                     LKYSGSEQEFILKEK"
     gene            6164..6724
                     /locus_tag="KRH23_003509"
     CDS             6164..6724
                     /locus_tag="KRH23_003509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HHS5226779.1"
                     /translation="MFCSNCGAEITGIGKFCSSCGVAVETEIIEDNNIKSNDLIVDAN
                     GIEINMTEIYRKYRKEKVNAIKNVMEISGLNIKEAKKIVDFSFEELKINFIDDTMSNS
                     EKEKIIQNQNRKNNIEKAQQESVACCPKCGSTSLTAQKKGFGIGKAMVGASLTGGIGL
                     VAGNLGAKKVRVTCLNCGKQFWAGKK"
     gene            6802..9090
                     /locus_tag="KRH23_003510"
     CDS             6802..9090
                     /locus_tag="KRH23_003510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HHS5226780.1"
                     /translation="MATIQTSIRIFDGMTPAFRHMTTAMNIVLSSFEQLQRTSSNAVN
                     ANSIIRAREELARAEAGFDRLERQIRESDNQQRKLNEDINKGASSTDRLVGSAKKLAA
                     TYLGIRTLGGLGNLSDQMTSTNARLGMINDGQQSDAGLNKMIFQSAERSRASYLDTAQ
                     IVSRIGMNAGKAFSSTKEIVGFAEQLNKKFVIAGASTEEMNSALLQLTQGLSSGVLRG
                     EELNAVFESAPNIIQSIADYLDVDIGKIRGMASEGMLTADIVKNSLLAAAEQTNAEFE
                     KMPYTFSQIWTSIKNNAIMIFGVIQKKIEQSMSSKGFRTFIDNFINSLYVLGNVAYNI
                     FNEIISILGSPFFQAFVNAIIVGVSLIVQALGWIITQALNIANVFAQNWSIIAPIVLG
                     VAAAMLVYNNALLLSIANKVKDIALSAKSLVMSFAHIVAESYRAAALVATTIAQDGLN
                     AAMAACPITWILYGIIAIVVAFFVAIAIFNHFAGTSVSAIGVVAGAISVAASFIGNLF
                     IATGNLIIDIVALIYNTLAGFAEFFANFLDDPIGSVIRAVSGMANAVLGIIRSIASAF
                     DTVFGSNLADAVSGWQDKLQGWTDKVAGEAKIKVERMDPNKLHFDRFNYGKAWDAGYK
                     WGDKLETNIKDKFDISKMAEDAKKKLGLDDLWDKKYGLGDGFGSAGLNSPLNDAAKGA
                     KDTAGNTAKMAKTMDKSQEDLKYLRDIAEQETINRFTGVNIKIDMNNTNNISKDNDLD
                     GIVNVLTEKLNDAMAVSAEGIV"
     gene            9107..9808
                     /locus_tag="KRH23_003511"
     CDS             9107..9808
                     /locus_tag="KRH23_003511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HHS5226781.1"
                     /translation="MAYDFYLDGVQLPIAPPKLEVKVTNKNKTVDLINVGEVNILKKE
                     GLSEISFEAEFTHNKLPFYRGTFRDVQFFLSKLELLKTDCKPFQFIVSRELGNKVLFN
                     TNIKVSLEEYAISEDADNGSDTKVAIKLKQYRDYSTKKLVPATPEKTNYGRTPPPVMK
                     PKEFRPDSSNKPNGKTYTVKAGDSLWAICQKQLGNGSLYKKVYELNKTMMDKANKGKK
                     LSKYTIYKGQVLRLV"
     gene            9801..11771
                     /locus_tag="KRH23_003512"
     CDS             9801..11771
                     /locus_tag="KRH23_003512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdQ/YqbQ family protein"
                     /protein_id="HHS5226782.1"
                     /translation="MSDDLVLANDRDIRLVIAHWEDFYEPVVLDGITWEIERRGTPSK
                     LEFTIVMDDILEFCEGNSVRLYYKGVGIFYGYIFQKKRDKENHIKIVAYDQLRYFKNK
                     DTYVYSNKTASELVKMLAKDFKLKYNVIEDTKYKISRVEENKTLFDMVLTALDDTLRE
                     KKEMYVLYDDFGRITLKNVASMKLDTVMNNDVIEDFDYNSSIDSDTYTKIKLVRDNEE
                     TGKRDVYIAQDSTHMRSWGILQLFDTVDKNMSEAEIKQKCDILLKLYNKKTKSLSLKN
                     VLGDIRVRAGCLVPVFLSLGDIDLQNYMLVEKVKHTFENNSHFMDLTLVDGDEFASYS
                     SSSYSSGNTNNKNEKQNGPAQSTTSKEDTDMANKINKLLKGKLSNTGNIFVKYSNAYK
                     VNPALMAAISMHESARGTSNIANTKNNFFGMKKNGDYMSFSSVDEGIKRGISNLSRNY
                     IHIGRKTLESIRNKYSSSSDKEWVKCVGAFYKQITGSTYNSNSAGTGVGSNEEAEKNL
                     KDLTYQVQNNNSNTSTNNNNKVSKVIQEAKNQLGKPYKWGGNGPKSFDCSGLMVWAFK
                     RGAGINLKRVSADQSKDSRGKLLCNINDVKAGDLVFFAYNKGKGNVHHVGLYIGNDQY
                     IHAPQTGDVVKISSLSGRQKKKHDFARARRFF"
     gene            11785..12045
                     /locus_tag="KRH23_003513"
     CDS             11785..12045
                     /locus_tag="KRH23_003513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2577 domain-containing protein"
                     /protein_id="HHS5226783.1"
                     /translation="MSQELLQIIKKAAMDAVETSNPMQIAFGTIESVNPLIVKIEQKA
                     SFEEFFLIQTETFKRYTDKKIGDKLVLIRMQGGQQYLILDRM"
     gene            12050..>12279
                     /locus_tag="KRH23_003514"
     CDS             12050..>12279
                     /locus_tag="KRH23_003514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2634 domain-containing protein"
                     /protein_id="HHS5226784.1"
                     /translation="MLPTDNIDYDIEDVSIINFDVRQEPSKTFKLNIEKNRVDGICDD
                     VEALKQTIFLILNTERYEHLIYSRNYGVELND"
BASE COUNT         4885 a         1327 c         2441 g         3626 t
ORIGIN      
        1 ataatggcac aagtaaggaa attaaataga atattaacca tagaagagtg taaaatagat
       61 gatttcttag agatgggata tgatttgata gatgaaactg gtaaggtagt aaggtatggc
      121 aagtcattaa atgtaaaaga tttaatagct gaaaataata ttttaaggtc aaaagttgag
      181 tctttagaag aagaaaataa gcagcttaaa gagaaaaata aacttactaa aaagtaggtg
      241 aaaattatgg gaaataatat aattgatgat atagaaaaaa gacttgaaag ttttggatat
      301 atattaaaag atggggataa gtggttaata gattttgtaa gagaaaaaat agaaaatatt
      361 attaaactag attgtaatat aaaaactatg ccaattgaat tgaaagaaat tgaagctgat
      421 atgatagttg gagagttctt atttaccaag aaaaatatgg ggcaattaga tatagaaagc
      481 attaactttg aagctgtaga aaagtctata tcagaaggtg atacaaaggt agatttcgct
      541 ataggaagtg gctctcaaac accagaacaa cgctttgata gcttaatagc ttatcttact
      601 gcttatggta agaataagat attaaccttt aggtgcttaa gatggtaagt aaaactagaa
      661 aagcaataga aatgttatat agatataaat gtactatagt tgagtatcag ccaatcaaag
      721 accctgtaac aaaacgaact aacaataaag aagtgattgt attagaaaat caaccatgca
      781 agctttcata taaaaatata gtttctgcta cagaaggaaa attagctaag ctagagcaaa
      841 ctattaaact ctttatatct ccagatatag aaattaaagc aggttcaaaa cttattataa
      901 atgataaaga gtatgtaaga agtggagaat cagctatata tccaaatcat caagaaataa
      961 tacttgagtt atttaaggat aaagcataat ggctagatgg ggcagtgttg attttagaga
     1021 gtttaaaaga gtttgtaaaa agatggagaa gcttacaaag attgatttag ataagttttg
     1081 caaagatgca gcaagagaat tagcagcaag actcttagga aaagtaatta gaaggacacc
     1141 agttgataca ggattcttaa gacaaggatg gaatggagtg gcttatgcta ggtcgcttcc
     1201 tgtgtataaa caaggaaata attatattat agaggttgtt aatccgactg aatatgcaag
     1261 ttatgtaaat ttcgggcata gaactaaaga cggaaaaggt tgggttaaag gacaacattt
     1321 cttaacaatt tcagagatgg aactacaaag ccaagttgat aagattatag agaaaaagtt
     1381 attaatatta cttaaaggag tatttgatgc ttaataatat tatagatgga atatcagtaa
     1441 agttagataa atcatttgga gaaaaatata caatttatag tgaggatgta gagcaaggta
     1501 ttaatgaacc ttgttttttt attgttcctt taaatccaag caagacacca tatccaagcg
     1561 ggagagaatt aaagaaaaat tcttttgatg tacattattt ccctcgttca gaagctaaga
     1621 attttgaaat aaatgagata gctgagatgt tactggaaga attagagtat atagaaatca
     1681 atggagattt agttagaggc acaaatatga attttgaaat tatagacaat gttcttcact
     1741 tctttgttga ttataactac ttcactataa agagtaataa tgcagataaa atgaatacag
     1801 tagagttatt cggtggtttg aagagaggtg ataattttga gtaagacatt aagcaaagga
     1861 accgattaca agtttactaa ggagcagata gttaattcta agaagtatgt aaatagaaaa
     1921 gacttattaa atgcaatttt aaaagaaaat gagttatatt ccttctcaga agtagaggat
     1981 agaataaata aattcatgaa aggagtgagt tagatggctt taggtggagg aacatttgta
     2041 acacagaata aagtattacc aggtagctat ataaactttg taagtgccac aagggcaacc
     2101 agttcactta gcgatagagg tattgttgca atgcctttag aacttgattg gggaattgat
     2161 gaagaagtat ttcaagtgac tagtgatgat tttgagaagt attcaactaa gtattttgga
     2221 tatgattata cacatgagaa gttgaaaggt ttgagagatt tatttaaaaa tataaggcta
     2281 ggatatttct ataaattaaa taaaggtgtt aaagctagtt gtagtattgc tacagctaga
     2341 tgcagtggta taagaggtaa tgacttaaaa gttatagtaa caacaaatat agatgataat
     2401 gctaaatttg atgttgtaac acttttagat aataagaaag ttgatactca aatagctaaa
     2461 gttattacag aactgcaaga taatgattat gtcacttgga agaaggaagc aacattagag
     2521 gctacagcag gattaacttt tactaatgga actaatggtg aagctgtgac aggaacagag
     2581 tatcaagctt ttcttgataa gatagaaagt tactcattta atgcactagg atgtttggct
     2641 acaacagcag agattaaaag tttgtttgta gagtttacta agagaatgag agacaaagtt
     2701 ggggctaagt ttcaaactgt attatataaa aagaatgatg cagattatga aggtgtagta
     2761 tctgttgaaa ataagattaa agatactgga ttattagaat ctagcttaat ttactggact
     2821 actggagcta tagcaggatg cgatataaat aaatctaata ctaacaagcg atatgatggt
     2881 gaatttgatg tagatgttaa ttacactcaa atacatttag aagaagcttt aaaaactggt
     2941 aagtttatat ttcataaggt tggagatgaa gttcatgtat tagaggatat aaatactttt
     3001 gttagtttta cagatgaaaa gaatgacgac ttttcaagta atcaaagtgt tagagtactt
     3061 gaccagattg ctaatgatat agcgacttta tttaatacaa agtacttggg tgaagtacca
     3121 aatgataaat ctggtcgtat ctcgttttgg aatgatgtag ttaagcatca tgaacaactg
     3181 caaaatatga gagcaataga agatttcaaa gctgatgatg tttctgtaga acctggaagc
     3241 gacaagaaga ctgttgtagt aagtgatgct gtaaaagtta ttagtgctat gagtaagctt
     3301 tatatgactg tttcagttag ttaacaataa gaaaggagaa taataatggc acaacaaata
     3361 aaagcaagag atacaataag tgcatctaag gcagagtgtt ttgtaactat aaaaggtaaa
     3421 agatataatt ttatgcaagc tattaactta gaagctaaaa tggaaaagaa taagagtgag
     3481 atacctatat taggtagtac tacaaaagga aataaatcaa caggaagtaa atattcagga
     3541 aatgcaacat tttattataa tacctctata tttagagaat tgttgtatga gtataaagaa
     3601 actggtgagg atatttactt cgatatacaa attaccaatg aagacccaac aagttcagtg
     3661 ggtcgtcaaa ctataatact ggaagattgc aatatggact caggcataat tgctaaattt
     3721 gatgctgatg gggagtattt agatgaagat atggatttta cttttgagaa ttggaaatta
     3781 gttgagaaat ttaatatagc aaatggtatg gagtaaaata cacatttatg atttatgtat
     3841 gtgtattttt tatttataag aataggagat gattaaaatt aaggataaat atgagataaa
     3901 agattcaatt tcttttgatt atagcaataa aagacctttg gaagaacgtg tcagcgagat
     3961 gtataaaaag gcaggaaaat atcttataga tatttcagat aagttagcaa cagatacaat
     4021 tgatggttcg tcattaaagc caataatcat aaaatttgaa ataaatgaag ctggtgttgc
     4081 aacaatagaa aaacaaacaa aatatttggt gatggaggta gaataagaat atgggagatt
     4141 taaacgcttt tttaagtcaa aatgcaataa aagtagagaa tagaaagtat gtggcaagtg
     4201 aaaggtttat aggagaagat ggaaaagcaa tcgaatggga acttaaagca atagattcag
     4261 atagagatag acaattaaga aaagattcaa ctataagagt acctgtacta aataaaaaag
     4321 ggaaagcaac agggcaatac actagtgaaa cagattttaa tacttatact ttgaaactgt
     4381 gtgtagaaac tgtagtattt ccagatttac atgatgcaga acttcaaaat agctatggtg
     4441 taatgggagc agaggaacta ttaacaacaa tgttaactcc tggtgaatac acagaccttt
     4501 caagtgaggt aggagaagtg aatggttttg ataggacttt tgaagataaa gtagaagaag
     4561 caaaaaacta attgaaggag gcgattatga tgctagtgta gctcattatt gccttcataa
     4621 attcaaatgg aaaccacatg aatatacaga tttaccagac ttcgagaggg catttgttgc
     4681 tgcttctata gatattaaag tagaagaaga aataaaagaa gaaaaaaaga ttgctaaaga
     4741 agctagaaga agtagaagaa gataaaatat aggtaaaata tgtaagaatt atatgttata
     4801 ataattgtag caagaagatg taatctacaa tttatagagt ggagttcata ctgggataaa
     4861 acctacttcc taatgaaagg aggtgggaag tatggacaat tttttactta gtatattagc
     4921 tagcttgata gctagtttaa ttggatatat cgtttgtaga tgtatcaaaa acgtaaaaag
     4981 ccactctact cgtggcaaga gtaaaagtgg ctgggaactt ggttttaaaa taaagttccg
     5041 caaatttaaa taatttatat tttttaaaat tatgaacttc actctaccgc taaatagatt
     5101 gtagttcttc ttgcctttat tataccacaa attagaaaaa atatgcaaag tacttgtttt
     5161 aatagtaagt acttttttta tgtgaaaaag aaggtgattg aatgaataaa gatatagaac
     5221 ttacagaaaa agatttatat tgtattgcta gacatattca agtgtatgtg tttaaaaaag
     5281 atgatgaggt cataaaaaag gaagataatc catgttgcag atgcaagcat aaatttaagt
     5341 attatgagaa tagtgtatgt atctatcatt gttcagtatt tcagaagtta tctaaaatta
     5401 caggtcttaa aatgggtttt ggagtcaaac tataatgtaa aaattttgaa tatatagtat
     5461 aatattctta taaaatataa tttaggggga tattatgaga gaaggaaaga gaagaagagg
     5521 atgtctattt tggtttatca ttattattat attttctggg gttgttggag caatagcagg
     5581 gaacagtact aataatggaa gcactgaaaa acaaaaagaa gatttaacta aatatattgg
     5641 tgaagaaggt aatataggag atttaaaatt aactgttaat agtatttcaa aagctagtga
     5701 aataccagta gcttctggtt atttggcgta cactccagat agtggcaaat atggtattat
     5761 aaatttaaca ataaaaaatc aaactaagga aagccaatct tttatgctaa attcattcac
     5821 attaatagga ccagataatt caaaatatgt tccatcttta ttgattgatg taggaaataa
     5881 atatataact atggatactg taaatcctaa tttagatgta acaggtaata ttgcatttga
     5941 aattcctaag gatttactag tttctgattg taaactaaaa tatagtggtt cagagcaaga
     6001 atttatatta aaagaaaaat aatatataga tttaaaatca aaaatactaa aaacacttac
     6061 taatgtaggt gtttttttaa tgaaaggatg tgatgataat gtaaaatttt tactaatata
     6121 gtataatatt cttataaaat tattatactg ggggggaaat gttatgtttt gttcaaattg
     6181 tggtgcagaa atcacaggca taggcaagtt ttgttcaagt tgtggggttg ctgtagaaac
     6241 tgaaattatt gaagataata atattaaatc aaatgactta atcgttgatg ctaatggaat
     6301 agaaataaat atgactgaaa tttatagaaa atatagaaaa gaaaaagtaa acgcaataaa
     6361 aaatgtaatg gaaataagtg gtttgaatat aaaggaagca aaaaaaatag tggatttttc
     6421 ttttgaagaa ttaaaaatta attttattga tgatactatg agtaattcag aaaaggaaaa
     6481 aataatacaa aatcaaaata gaaaaaataa tattgaaaaa gctcaacaag aatcagttgc
     6541 ttgttgccct aagtgtggtt caacatcctt gacagctcaa aaaaaaggtt ttggtatagg
     6601 gaaagcaatg gtaggagcta gtctaactgg tggtataggt ttagtagctg gaaatttagg
     6661 agcaaagaaa gttagagtta catgcttgaa ttgtgggaag cagttttggg caggcaaaaa
     6721 atagatgtat taattataaa aacacttact aatttagtaa gtgtttttat tatctaaatt
     6781 aacagaaagg agagtgaaaa aatggctaca atacagacat caattcgcat atttgatgga
     6841 atgacacctg cgtttcggca tatgacaact gctatgaaca tagtactgag ttcatttgag
     6901 caattacaaa gaacttctag taatgcagta aatgctaata gcataataag agctagagaa
     6961 gaactagcaa gagcagaagc tggatttgat agattagaac gacaaataag agaatcagat
     7021 aatcaacagc gaaaacttaa tgaggatata aataagggtg caagttctac agatagatta
     7081 gttggaagtg caaagaagct agcagcaact tatttaggta taagaacatt aggaggtcta
     7141 ggaaatttaa gcgaccagat gacaagtact aatgcgagac ttggcatgat aaatgatggg
     7201 caacaatcag atgctggact taataaaatg atatttcaat cagctgaaag gtcaagagca
     7261 tcttacttag atactgcaca aatagtgagt cgtataggca tgaacgcagg aaaggcgttt
     7321 agcagtacaa aagaaattgt aggttttgca gagcaattaa acaaaaaatt tgtaatagca
     7381 ggcgcaagta ctgaggaaat gaactcggca ttgttacagc taacccaagg gttgagttct
     7441 ggcgtattaa gaggtgagga actgaatgct gtgtttgagt cagcacctaa catcatccaa
     7501 tcgattgcag attatttgga cgtggacata ggaaaaataa gaggaatggc atcagaggga
     7561 atgttaacag cagatattgt aaaaaactca ttacttgcag cagcagagca gaccaatgca
     7621 gagtttgaaa aaatgcctta cacattttct caaatttgga cttcaattaa aaataatgca
     7681 atcatgatat ttggtgttat acagaaaaaa attgaacagt ctatgtctag taagggattt
     7741 cgaaccttta tagataattt tataaactct ttgtatgtac ttggaaatgt tgcttataac
     7801 atttttaatg aaattataag tatattaggg agcccgtttt ttcaagcatt tgtaaatgcg
     7861 attattgtag gtgttagttt aatagtgcag gcactaggtt ggataataac acaggcatta
     7921 aatattgcta atgtgtttgc tcagaactgg agtattattg caccaatagt acttggagtt
     7981 gcggctgcta tgttagtgta taacaatgcg ttattactta gtattgcgaa taaagttaaa
     8041 gatattgcac tatctgccaa atctttagtc atgagctttg cacatatagt agcagagtct
     8101 tatagagcag cagctttagt agcaactaca atagcacaag acggattaaa tgcagcaatg
     8161 gcagcttgtc ctattacttg gattttatat ggaattatag ctatagttgt tgcatttttt
     8221 gtagctatag caatatttaa tcacttcgca ggcactagtg tatctgctat aggtgtagtt
     8281 gcaggtgcaa tatcagttgc agcctctttc ataggaaact tatttattgc aacaggaaat
     8341 ttaattatag atattgtagc tttaatatac aatactttag caggctttgc agagttcttt
     8401 gctaattttt tagacgaccc aattggctct gttataagag cagtatccgg aatggctaat
     8461 gctgtattag gcattataag aagtatcgca agtgcatttg ataccgtgtt tggttcaaac
     8521 ttggcagatg cagtaagtgg atggcaagat aaattgcaag gttggactga taaagtagca
     8581 ggagaagcta aaataaaagt cgaaagaatg gaccctaata aactgcattt tgacagattt
     8641 aattatggaa aagcatggga cgcaggatat aaatggggag ataagttaga aactaatata
     8701 aaagataaat ttgatattag caaaatggca gaagatgcaa agaaaaaatt aggattggat
     8761 gatttatggg ataaaaaata tggattagga gatggatttg gttcagcagg attaaactct
     8821 cctctcaatg atgcagcaaa aggagcaaaa gacactgcgg gaaatacagc aaagatggct
     8881 aaaacaatgg ataaaagcca agaagactta aaatacttaa gagacatagc agaacaggaa
     8941 acaatcaata gatttacagg agtaaacata aaaattgata tgaacaacac aaacaacata
     9001 agtaaagata atgacttaga tggaatagtt aatgttctaa ctgaaaagtt aaatgatgca
     9061 atggctgttt cagccgaagg aatagtttag gaaggagagt gagaaaatgg cttatgattt
     9121 ttacctagat ggagtacaac taccaatcgc accaccaaag cttgaagtca aagtgacaaa
     9181 taaaaacaag acagttgatt taataaatgt tggagaagta aatatattaa aaaaagaagg
     9241 attatctgaa ataagttttg aagcagaatt tacacataat aaactaccat tttatcgtgg
     9301 aacttttagg gatgttcaat tctttttaag taaactggaa ctactaaaaa ctgattgtaa
     9361 gccatttcaa tttattgtat cgagggaatt aggtaataaa gtactattta acactaatat
     9421 aaaagtatct cttgaagagt atgctatttc agaagatgca gataatggct cagatacaaa
     9481 agttgcaata aaattaaaac aatatagaga ttactcaact aaaaagttag ttcctgcaac
     9541 tcctgaaaag acaaactatg gtaggactcc ccctccagtc atgaaaccaa aagaatttag
     9601 accagattca tccaataagc caaatggtaa aacatataca gtaaaagcag gggattctct
     9661 ttgggcaatt tgtcaaaagc aattaggaaa tggttcgtta tacaagaaag tatatgagtt
     9721 aaataaaaca atgatggata aagctaacaa gggaaaaaaa ttaagtaaat acaccatcta
     9781 taaagggcag gtgttgaggc ttgtctgatg atttagttct ggcgaatgat agagatataa
     9841 ggctagttat tgcacattgg gaagatttct acgaacctgt agttttggat ggtatcacat
     9901 gggaaataga gagacgagga acaccatcta aacttgaatt tacaatagtc atggatgata
     9961 tattagagtt ttgtgaaggt aactctgtaa gactatatta caaaggtgta ggtatattct
    10021 atggatatat atttcagaaa aagagagata aagaaaatca tatcaagata gttgcttatg
    10081 accagctaag atattttaag aataaagata cttatgtata tagtaataaa acagcaagtg
    10141 aacttgtaaa gatgttggct aaggatttta aattaaaata caatgtcata gaagatacaa
    10201 aatataaaat atcgagagtt gaagaaaata aaacactctt tgatatggtc ttaactgcac
    10261 tagatgatac tctaagagag aaaaaggaaa tgtatgtttt atatgatgat tttggaagaa
    10321 taacattaaa gaatgttgct tctatgaaac ttgatacggt tatgaacaat gatgtaattg
    10381 aggactttga ctacaattct tctattgata gtgatactta cacaaagatt aaacttgtga
    10441 gagataatga agaaacagga aaaagagatg tgtatattgc tcaagactca acgcatatga
    10501 ggagttgggg aatactacaa ctatttgata cagttgataa aaatatgagt gaagcagaga
    10561 taaaacaaaa atgtgatata ctcctaaaac tatataataa gaaaactaag tcattaagtt
    10621 taaaaaatgt gttaggagat attagagtaa gagcaggttg tttagtacct gtttttttgt
    10681 cgttaggaga tattgattta caaaattata tgttagttga gaaagtaaaa catacatttg
    10741 aaaataacag tcattttatg gacctaactt tggttgatgg agacgaattt gcttcttatt
    10801 cttcatcaag ttatagtagt ggaaatacta ataataaaaa tgagaaacaa aatggtcctg
    10861 cacaaagtac tacaagtaaa gaagatactg atatggctaa taagattaat aaactactta
    10921 aaggtaaatt atcaaataca ggaaatatat ttgttaaata ttcaaatgct tataaagtta
    10981 atccagcact catggctgct atatctatgc acgaatcagc tagagggact tcaaatattg
    11041 caaatactaa aaataatttc tttggaatga aaaaaaatgg agattacatg agtttttcta
    11101 gtgtagacga aggaataaaa agaggtataa gtaatttatc aagaaactat atccatatag
    11161 gacgaaaaac tttagaaagc atcagaaata aatattcttc tagttcagac aaagaatggg
    11221 taaaatgtgt aggtgcattt tataagcaaa taacaggaag tacttataat tctaatagtg
    11281 caggcacagg agttggaagt aatgaagaag cagaaaagaa tttaaaagat ttaacttatc
    11341 aagttcaaaa caataattct aatacatcaa caaacaataa taataaagta agtaaagtta
    11401 ttcaagaagc aaaaaatcaa cttggcaagc cttacaaatg gggtggtaat ggtccaaaga
    11461 gttttgactg tagtggtctt atggtgtggg catttaaaag aggtgcagga ataaatctca
    11521 aaagagtttc agcagaccaa tcaaaagata gtagaggaaa actattatgt aacataaatg
    11581 atgtaaaagc tggtgattta gtattctttg catacaacaa aggaaaagga aatgtacatc
    11641 atgttggact atatatagga aatgaccaat atattcatgc tccacaaact ggtgacgtag
    11701 taaaaataag tagtttaagt ggtagacaaa agaaaaagca tgattttgca agagctagaa
    11761 gattctttta agtgaggtga taaagtgtca caagaattat tgcaaataat taagaaggct
    11821 gcaatggatg cagtagaaac aagcaatcca atgcaaattg catttggaac tatagaaagt
    11881 gttaatcctt tgatagttaa gatagaacaa aaagcatctt ttgaagaatt ttttctaata
    11941 caaacagaga cttttaaaag atatacagat aaaaaaatag gggataaatt agtcttaatt
    12001 aggatgcaag gaggacagca atatttgatt ttagatagga tgtgatgaaa tgttaccaac
    12061 agataacatt gactatgata tagaagatgt atcgataatt aattttgatg ttagacaaga
    12121 accaagtaag acgtttaaat tgaatataga gaaaaataga gtagatggta tttgtgatga
    12181 tgtagaagca ttaaaacaaa ccattttttt aattttaaat actgaaaggt atgagcacct
    12241 tatttattct agaaattatg gtgttgaatt aaatgattt
//
LOCUS       DAEORM030000090        11478 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.096, whole genome shotgun sequence.
ACCESSION   DAEORM030000090 DAEORM030000000
VERSION     DAEORM030000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11478)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11478)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 11478)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11478
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.096"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            complement(62..2173)
                     /locus_tag="KRH23_003515"
     CDS             complement(62..2173)
                     /locus_tag="KRH23_003515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HHS5226785.1"
                     /translation="MTINKLYSKLRAYNWKNYTTLFFCIILSVVLVTSYALIYFSPTI
                     QNILPTGGDSRKQATMIFSVAILGCTVFTTYASSLFLKFKSKEIGIFMALGTDKKKLK
                     KLLFSEILLISIVCCFLGLILSIPVSFGIWKIFQLVIIDTREMTYHFGTQGFIYGFIF
                     SIFVTLCIFILSVKFINRTNIIDILNDQRISEPIQDVKDWYGILGIIFIILGIFLGYL
                     VPSLTINKLNYKLPSIWSFTYLLSLIGIYMIMTYIVVHAKRGKHPEKYYKNIISTSMM
                     RFMGRQTVKNMCVISFLIAGALFAVFYVPNMVTGIYDTLKNNPIDYTFTYNQRDKQVS
                     KKDIEQLADKHNIKIQNYMEIPSIELIVDGVESIYHKDGTIEKVYMKKSSYDMFFNSK
                     DFSKLIGKPITIKNGEYLAVVNKGNENQDYKYTKFISSPVTEKEIPFRYAGKIIFNGS
                     FFQNRSMNAYVLNEEDYKSFTKDLSIKNYNNSILFNVDKDTYAFANDLKKEIIKRTSK
                     EMGMFSGYDEYVKKRYESTGRKYFMDEEYPSGEGHLKLDPNNNQLYLNWKYYPNFKIL
                     QSQDMIKNMAVFLMLFIYVAIICFTAVGIIAYTRGVTIAINHKQVFMDLNRLGANNDY
                     IKFCIRNQLKKVFSYPLIAGSFLIYLFNFMIMLNNDGRIVNSEVNALLINLGFIGICG
                     VYMYLIYLLTYKKFKKIIGIL"
     gene            complement(2163..2915)
                     /locus_tag="KRH23_003516"
     CDS             complement(2163..2915)
                     /locus_tag="KRH23_003516"
                     /EC_number="7.6.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHS5226786.1"
                     /translation="MLKVNQLCKSYKAGNKTYPVLKNISFEINKGEFVAIMGSSGSGK
                     TTLLNCISCFIPIDNGEIILGNNNIRNLKEKELSEVRNQQLGFVFQDFMLFDGLSVFE
                     NICVPQIIKGSQVLQMENRAINLCELFGIEHIRKKYPAEISGGEKQRTAVARALMNNP
                     DLILADEPTGNLDSKSCRTVIESFLKAKQELDATILMVTHDSFAASFCDRVIVLKDGI
                     IYKEVVKSNSRHKFLDELLEVLKEMGGAQDDN"
     gene            complement(3920..4096)
                     /locus_tag="KRH23_003517"
     CDS             complement(3920..4096)
                     /locus_tag="KRH23_003517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226787.1"
                     /translation="MFFTFIGVISAILLLCTIICGLWIKLNNRNNDSNSHFTFSILSI
                     AFSLLIVVAFLVRN"
     gene            complement(4200..4781)
                     /locus_tag="KRH23_003518"
     CDS             complement(4200..4781)
                     /locus_tag="KRH23_003518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HHS5226788.1"
                     /translation="MKSDSTKEQLINATIQLLSSHRDVSNITAREIVAKANVNLAMIN
                     YYFKSKEELINTSIKKFLKRHMDEYKATHNTKNLAPKQQLREILIAFFDFIGEHSQFI
                     KISVPYILIQEEIVYPFEILPLIKAHYENQNNKKTEAEYRTIAYQITSFIQLLFLRSN
                     AFFKYSGIDILNIEQRNGLIDFQLDLLLVDITK"
     gene            complement(4907..5731)
                     /locus_tag="KRH23_003519"
     CDS             complement(4907..5731)
                     /locus_tag="KRH23_003519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HHS5226789.1"
                     /translation="MFKIGEVSKLTQISIRMLRYYDELGILKPAEIDKYTGHRLYSVE
                     QISILQRIVLLRDSKFSVAEIANIVHNWNDEFVIKELNRKKNEIQKEIKQEQQRINKI
                     DKFIEAINCDKDEIHYNVVFKKIPSYKIISLREIIPDYQSEGILWEKLSKFIKEEHIE
                     VSRQSNNNIAFYHDEEVKDNGVDIEVGMVVKKIGKNKSGFIYRETEEIDMMACTMVYG
                     PYENIAGAYESFCYWLDKNSDYQISGINRQIGHKGEHNEINPENYLTEIQIPLIKV"
     gene            complement(5909..6802)
                     /locus_tag="KRH23_003520"
     CDS             complement(5909..6802)
                     /locus_tag="KRH23_003520"
                     /EC_number="3.4.26.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family glutamic-type intramembrane
                     protease"
                     /protein_id="HHS5226790.1"
                     /translation="MQLYNTPFNTNKHLIYFFTFTLVLNWIFSLTPALLGITNTILGE
                     IIFYLAYTSPAIVGLFFISTIYPQSAKQDFIYRYLSFKEIGIKWILLTILFFALTFIT
                     SLIIGNYFNVKTSDIDWIHIAVFRPSKIAYMLVASFILSILSQEAGWRGYAIDKLLVR
                     FGFIGSSIILGLVCGIWYLGSYFTPNQIPYNLAQYSLFDAFLFIPNIVLLNFIINFVY
                     INTSRSILSAGLVHMMYYFFNIQLLLHYPIKLCVIAQYVQIIFGLIFLVYMISSNKFK
                     QKVNSEIEQIKSDDFEFELDW"
     gene            complement(7059..7496)
                     /locus_tag="KRH23_003521"
     CDS             complement(7059..7496)
                     /locus_tag="KRH23_003521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family DNA-binding domain-containing
                     protein"
                     /protein_id="HHS5226791.1"
                     /translation="MKIHVEQGINCDDIEITIKCSALDNNIEKIISLLSIPLLDIKGK
                     KSGEIYKLNVCDILYFETVGNKTFAYYEDDVFEIDLKIYKLSKLLANTSFSRISKSMI
                     LNMDYIKSIKVISHNRMQATLKNNEKVIINRRYIKNIKEKLNI"
     gene            complement(7753..7902)
                     /locus_tag="KRH23_003522"
     CDS             complement(7753..7902)
                     /locus_tag="KRH23_003522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvrJ family protein"
                     /protein_id="HHS5226792.1"
                     /translation="MDDSLQLLITNVGFPIALSMYLLVRIEGKLNTLSNSIDTLSKNI
                     LIFKK"
     gene            complement(7915..8145)
                     /locus_tag="KRH23_003523"
     CDS             complement(7915..8145)
                     /locus_tag="KRH23_003523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2922 domain-containing protein"
                     /protein_id="HHS5226793.1"
                     /translation="MEIKKKLVMSFKNVKDKQVSFSIENPKDDLTEENIKSVMDLIVS
                     KNIFSVGGFDLASVVEAKVVETNTTPYDLVIE"
     gene            complement(8583..8804)
                     /locus_tag="KRH23_003524"
     CDS             complement(8583..8804)
                     /locus_tag="KRH23_003524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1659 domain-containing protein"
                     /protein_id="HHS5226794.1"
                     /translation="MEVVSTKNLSSIKLKLDAGFDDKGKAVVKSKSFANVKAEALNED
                     VYAVAEAIASLQENPIVDILKLDSTSLSK"
     gene            9384..9641
                     /locus_tag="KRH23_003525"
     CDS             9384..9641
                     /locus_tag="KRH23_003525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mor transcription activator family protein"
                     /protein_id="HHS5226795.1"
                     /translation="MKIKVEDIPVQFHAMVEIIGIDKFIEVAKLYGGTNTYIPTYKGL
                     FRYARNRDIVKQFNGVNHNELAIRYNMCVSNIKRILNENSV"
     gene            10110..11348
                     /locus_tag="KRH23_003526"
     CDS             10110..11348
                     /locus_tag="KRH23_003526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conserved phage C-terminal domain-containing
                     protein"
                     /protein_id="HHS5226796.1"
                     /translation="MNKGFYKLNSVVLNFDIKNDVNKIRFNHYIMRKENIQRLQGTLP
                     NGQFYMTVRRAATDLQLSISTISRLVKEFLDLGIIRLVSKGVKGNRSVYSYVSIEFNG
                     SLFDDSKYMELDCVCNDEFIDNSGIEFDCDSKDNSFNGDINVETVHCINEYFSDDDVE
                     HNYNNFHNKDTIKDKAISNISTIKKYIDESFDTNKSENSNLQQESINFNFNDTCNEID
                     KRTNNSIENNQNKRPMRLSDISVLSDKGMTNKKNYFNHNHGIQKGTKSVTKKKESLNK
                     FNKKNIQQSIINMLNKKSGKNFKIDSPISIKLINERLKEGYVLEDFYKVIEVKVAKWK
                     NTIMEMYIRPETLFSYKFESYVNENISMKSQSNVHPCKEGNSNDSSNYIHSDYTTYDG
                     SVRERKKYENVRYWNPICEI"
BASE COUNT         4273 a         1399 c         1530 g         4276 t
ORIGIN      
        1 acctttttta ttataaaaca ccaatgattt tattacttta aaaatctaac aaccttcctt
       61 attataaaat accaataatt tttttgaatt tcttgtaagt taatagatat ataaggtaca
      121 tataaacccc acaaatccct ataaaaccta agtttatcaa aagagcattg acctcactat
      181 tgacgattct accatcatta tttaacataa tcataaaatt aaacagataa attaaaaaac
      241 ttcctgcaat aagagggtat gaaaatactt tctttaattg atttctaata cagaacttta
      301 tataatcatt gtttgctcct aatcgattta aatccataaa gacctgcttg tgatttatag
      361 ctatagtaac accccttgta tatgcaatga ttcctactgc tgtaaaacat atgattgcca
      421 catatatgaa taacattaag aagactgcca tgttttttat catatcttgg ctttgtaaaa
      481 ttttaaagtt aggatagtat ttccaattaa gatacaactg attgttgttt gggtctagtt
      541 ttaaatgacc ttcaccactt ggatattctt catccataaa atattttctt ccagttgatt
      601 cataacgttt ttttacgtat tcatcataac cactgaacat gcccatttcc ttagatgttc
      661 tttttataat ttctttcttt aagtcattgg caaaagcata ggtatcttta tctacattaa
      721 atagtataga attattgtaa ttttttatgg ataaatcttt agtaaatgat ttataatcct
      781 cctcattaag gacataggcg ttcatacttc tattttgaaa aaaagaacca ttaaatatta
      841 tttttccagc atatctaaag gggatttctt tttctgtgac tgggcttgat ataaatttgg
      901 tatatttata atcttgattt tcatttcctt tatttacaac agcaagatat tcaccatttt
      961 ttatagttat tggtttgcca attagcttgg aaaaatcttt ggaattaaag aacatatcat
     1021 aggagctttt tttcatatat accttttcga tagttccatc tttatgatat attgattcta
     1081 caccatcaac aattaattct atagaaggaa tttccatata gttttgaatt tttatattgt
     1141 gtttatctgc taattgttca atatcttttt ttgatacctg tttatctctt tgattgtagg
     1201 taaaagtata atctataggg ttatttttaa gagtatcata gatacctgta accatattag
     1261 gaacatagaa tacagcaaat aatgctcctg caatcaaaaa tgaaataaca cacatgtttt
     1321 ttactgtttg tcttcccata aatctcatca tgctagttga tatgatgttt ttatagtatt
     1381 tctctggatg ttttcctctt ttagcatgta caactatgta tgtcataatc atatatattc
     1441 caataagaga gagtagataa gtaaagctcc atatagatgg tagtttataa tttaatttgt
     1501 ttatagttag tgaaggtacg agatatccta gaaaaatacc gagtataata aaaattatac
     1561 ctaatatacc ataccagtcc tttacatcct gtattggttc agatattctc tggtcattta
     1621 atatatcaat tatatttgta cgattaataa attttacaga aagtataaat atgcataatg
     1681 tcacaaatat actaaatata aatccatata tgaatccttg agttccaaaa tgatatgtca
     1741 tttctctggt atcaataatc actaattgaa atattttcca tataccaaaa gatacaggaa
     1801 tacttaatat aagacctaaa aaacagcata ctattgaaat taacaatatc tctgaaaata
     1861 gaagtttttt taatttcttc ttatctgttc ctagagccat gaaaatacca atttccttgc
     1921 ttttaaattt taaaaagagg gaagatgcgt atgtagtaaa gacagtgcat cctaatatag
     1981 caactgagaa tatcattgta gcctgttttc tgctatctcc accagttgga agtatgtttt
     2041 gtattgttgg gctaaaataa attagagcat atgaagttac taataccaca gaaagtatta
     2101 tacaaaagaa taaagttgta tagttcttcc aattataggc tcgaagttta ctgtataatt
     2161 tattaattgt catcttgagc gcctcccatt tcttttaaaa cttctagtaa ttcatctagg
     2221 aatttatgtc ttgaatttga ttttacaact tctttataaa ttattccatc tttaagcaca
     2281 ataactcggt cacagaagct tgctgcaaag ctatcgtgtg taaccatgag tatagtagca
     2341 tctaattctt gctttgcttt taaaaatgat tcaatgactg tacgacaaga cttactatca
     2401 aggttaccag ttggttcatc tgctaatatt aaatctgggt tgttcatgag tgctcttgct
     2461 actgctgtac gctgtttttc tccaccagat atttcggcag ggtatttttt tctgatatgt
     2521 tcaataccaa atagctcaca tagattaatt gcacggtttt ccatttgtaa gacttgacta
     2581 cctttgataa tttgtggaac acatatattt tcaaatacac taagaccatc aaatagcatg
     2641 aaatcttgga atacaaatcc tagttgttga tttctaactt ctgaaagttc cttttctttt
     2701 aaatttctta tattattatt tccaagaatt atttccccat tatcaattgg gataaaacat
     2761 gaaatacaat ttaaaagagt agtttttcca cttcctgatg aacccatgat tgcgacaaat
     2821 tctcctttgt tgatttcaaa agaaatattt tttaatacag gatatgtttt attgcctgct
     2881 ttatatgatt tacataattg gtttacttta agcatatata tcatcctcac tttcatttat
     2941 cttgtaagtc aatgatagca tttgaaaggg gaggagggat atgagctata ttgtaatagt
     3001 tggatgtttt tttgtaatgt ttgaaaatat attgtttgga tagtgtgaga ggttattatt
     3061 atagttaaat tgattatatt attggaggat ttagagggtt atttttaggt attaattgtt
     3121 gtgctaaagt aatatgatgt ggaacattga aggtgtagtt agaaaagaag tatatagtaa
     3181 aagtaaaaag gttatagaat aacgaatgtt gtattgaaaa aaatgatgta aataatgtat
     3241 agtagggtta aaaagaaaaa aagaattata gagcagtaag attatttaat ggaatgtatt
     3301 gtaaataatt tgaaaggatt taggggttat taacacaatg taattgagaa aatatattgg
     3361 agttttggaa ataaataggt tgttaaaaac aattgaaatg tataataaaa aggttaaaaa
     3421 gtattgttag tataggtatg atagataatt ttagaaagtg gaagtatttt agactatgct
     3481 gaaaagtgat tgatattatt ttgagatatt aaaatattac tatattatag taaagaagtt
     3541 aaaataataa aatgttgtaa taataaaggt ctgtagtata ataaagaact gtaataaata
     3601 agactttaca atataataga aatgttgcaa taacaaaaca ccataataaa taagagtttg
     3661 caatataata gaaacactgc aataaataag agattgtaat ataataaaag tctgtaatat
     3721 aacaaaatcc tataataaat aagattttac aatataataa aaatcctata ataaatagga
     3781 ctctgtaata taataaaatg ctgtaacaac aaaacactat aataaataag accctgtaat
     3841 ataataaaaa tactataata tagtaaaaat catgcaataa taaaaatcta taataataaa
     3901 ccccagcata acaaagacat taatttctta ctaaaaaggc cactacaatt aacagtgaaa
     3961 aagcaattga aagtattgaa aaagtaaagt gagaattaga gtcattatta cgattattaa
     4021 gttttatcca taaaccacat ataattgtac acaacaataa aattgctgat attactccta
     4081 taaatgtaaa aaacattaaa attcctcccc cttatttaat gcaagtattt ttagtcaatg
     4141 agaatatttt caaacgttac cataaaataa aaaaatgtac ataaaaaatt aatatagtat
     4201 tattttgtaa tatctaccaa taataaatct aattgaaaat ctattaaacc atttctctgt
     4261 tcaatattaa gaatatcaat accactatac ttgaaaaaag cattagaacg aagaaaaagc
     4321 aactgaataa atgaagttat ttgatacgca atagttctgt attcagcttc agtttttttg
     4381 ttattctgat tttcatagtg agccttaatt aaaggtagta tctcaaatgg ataaacaatt
     4441 tcttcctgta tcaatatata gggtacagaa atctttataa attgactatg ttcacctata
     4501 aaatcaaaaa atgcaattag tatttccctt aattgctgtt taggtgctaa atttttagta
     4561 ttatgtgtag ccttatattc atccatatga cgctttaaaa attttttaat agaagtatta
     4621 attaactcct ctttagattt aaaataataa ttaatcatag ctaaattgac gtttgcttta
     4681 gctacaattt ctctagctgt aatgtttgaa acatctctat gtgaagatag taactggatt
     4741 gtagcattaa ttaattgttc ctttgttgaa tctgatttca taatttttcc ccttaaaaat
     4801 ttccccataa aaaaattaaa catgtttaac acacgtttag atactatcat gaaaattttg
     4861 ggatgtcaat gggtgattag tacttaagta tttaagtact aatctattag acttttataa
     4921 gggggatttg aatttctgta agataatttt caggatttat ttcattatgt tcacctttat
     4981 gaccgatttg tctatttata cctgatattt gataatcact atttttatct aaccaataac
     5041 agaacgattc atatgcacca gctatatttt catatggacc ataaaccata gtacatgcca
     5101 tcatatcaat ttcttctgtc tcacgatata taaatccaga tttgttcttt ccaatcttct
     5161 ttacaaccat tccaacttca atatctacac cattatcttt gacttcttca tcatggtaaa
     5221 aagctatgtt attgttggat tgacgtgata cttctatatg ttcttctttg ataaatttag
     5281 atagcttttc ccagagtata ccttcagatt ggtagtctgg aattatctct ctaagtgata
     5341 tgattttata acttggaatc tttttaaaga caacattgta atgaatttca tctttatcac
     5401 agtttatagc ttctataaat ttatcaattt tatttattct ttgttgttcc tgctttattt
     5461 ccttttgtat ttcattcttt tttctattca attctttaat tacaaattca tcattccaat
     5521 tatgtacgat atttgctatt tctgcaacgc taaattttga atctctcaat aatacaattc
     5581 tttgtaatat tgaaatctgt tcaactgagt ataatctatg acctgtatat ttgtctattt
     5641 ctgcaggttt taaaatacca agttcatcat aataacgcaa catacgaata gaaatttgtg
     5701 ttagttttga aacctctcct attttaaaca tgaaaatatg acctcctttt cacttataat
     5761 cagtatatat tttgttttta tatacttcaa gcgtttgtgg aaatacaatt attttccaga
     5821 tgttgcaata aattatagag agtaaattat atttaagtag taatcgtatc aaatcataga
     5881 ttatcttaat ttataattca tattaaaatt accagtctaa ctcaaattca aaatcatccg
     5941 actttatctg ttcaatttca gaatttacct tctgtttaaa tttattagaa gaaatcatat
     6001 atacaagaaa tattaaacca aatattattt gtacatattg agctattaca cataatttaa
     6061 tagggtagtg tagaagtaat tgaatgttga aaaaatagta catcatatga actaacccag
     6121 ctgataaaat gcttctactt gtattgatat atacaaaatt aattataaag tttaaaagta
     6181 caatgtttgg tataaataaa aaagcatcaa atagggagta ttgtgccaaa ttatatggta
     6241 tttgattagg tgtaaaatac gaccctagat accagattcc acaaacaagc cctaaaataa
     6301 ttgaagaacc tataaatcca aatctaacta ataatttgtc aatggcatat cctctccatc
     6361 cagcttcttg actaagtata ctcaatataa aacttgctac tagcatataa gctattttag
     6421 aaggtctaaa cactgctata tgtatccaat ctatatcaga agtttttaca ttaaagtaat
     6481 ttccgattat taacgaagta ataaaagtta aagcaaaaaa taatattgtt aatagtatcc
     6541 attttattcc gatttcttta aagcttaggt atctataaat aaaatcttgt tttgcacttt
     6601 gtggatagat tgtagaaata aaaaatagac ctacaatagc tggtgatgta tatgcaagat
     6661 aaaaaatgat ttctccaagt attgtatttg taattccgag caacgcaggt gtaagactga
     6721 atatccagtt caatactaga gtaaatgtaa agaaatagat taagtgtttg tttgtattaa
     6781 agggggtgtt atatagttgc attttttcac tatccttccg ttttataatg aagttttaat
     6841 ttttattaat tgtttattta tttttatatg tattaagtta tcgcttgatg ttagttattg
     6901 cctataataa tatcctattt tttatatttt gattaattat ttttacacta aatataatta
     6961 attagtattt aatattgaat atattatatt attattaatt attaaatagg tcaataaatt
     7021 tgcaattagt gatattaata aattacttta gatttttatt aaatgtttag cttttcttta
     7081 atatttttta tataacgacg atttataata actttttcgt tgttttttaa agtagcttgc
     7141 atgcgattat gtgatattac ttttatactt tttatgtagt ccatatttaa aatcatggat
     7201 ttagatattc gtgagaaaga tgtattagct aataattttg ataatttata tatttttaaa
     7261 tcaatttcaa atacatcatc ttcataataa gcaaatgttt tatttccaac tgtctcaaag
     7321 tataaaatat cacagacatt gagtttataa atctctcctg attttttacc ttttatatca
     7381 agtaacggta tactcaataa tgaaattatt ttttcaatgt tattatctag agcagaacat
     7441 tttatggtta tttcaatatc atcacaatta ataccttgtt cgacatgtat tttcattaat
     7501 catcacctca ttttattact gtcattagaa tagcattata tcttattgag tccaactaga
     7561 tgcgttctaa atttcaaatt aagcatagtg aaattcaaaa ataaaacagt gaaattcaaa
     7621 tttgaggtgg taaaattcaa aaaaatacta tggatatttg gataaattat ccaaatatcc
     7681 tagtatttca catagaatat gtctaattat tttacaaata gacctatttt atgacttaca
     7741 tatattgtca aattacttct taaatatcaa aatatttttg gataatgtat caatactgtt
     7801 tgataaagta tttaatttac cctcaattct aaccaacaag tacatggata gagctatagg
     7861 aaaaccaaca ttggttatta acagttgtaa actatcatcc ataaaattag ccccctattc
     7921 tataactaag tcataaggag tggtatttgt ttccacaacc ttggcttcaa caacagaagc
     7981 taggtcaaat cctccaaccg aaaaaatatt tttagatact atcaaatcca tgacagattt
     8041 tatattttct tcagttaaat catcctttgg attttctata gaaaaagaaa cttgtttatc
     8101 ctttacattt ttaaagctca tgactaattt tttcttaatt tccatataat tacctccgat
     8161 ataataattt atattttaat tgtttgcttg ttaatattgg tatttcaatt gtcaatatta
     8221 gtgttttgct tgttagtatt aatatttcaa ttgtcaatat tagtgttttg cttgttagta
     8281 tcagtgtttc aattgtcaat attagtattt taattgttga ctctagttat tgctgatata
     8341 gaaatattta atttatttca attaattaga ttaaagtagg gtagcatcta aaatagctaa
     8401 catgtttaag ttgaaatacg tttaatatat taatttttca aagcgttaat atattaaagt
     8461 tataaccaaa attgaagtta taatctgcca aatctatagc gtattaagta cgttatataa
     8521 cttaatcttt tatataaaga gttaattttt taatttgtaa agcagagtac gtttaaaaga
     8581 tactatttag ataatgatgt actatctaat tttaaaatat ctacaatagg gttctcttga
     8641 agacttgcta ttgcttctgc aacagcataa acatcttcat ttaatgcctc tgcttttaca
     8701 tttgcaaatg atttactttt aacaactgcc ttacccttat catcaaaacc agcatccaat
     8761 tttagtttta tactagataa attttttgtt gaaacaactt ccataaaatt acctcctaaa
     8821 aatttaattt caaagatttg tcgactttct ttgttagcta taatactatc atctaagata
     8881 atatcggagt taaacagtaa tttctaaaga ttttttgtgt aaatttttat aggaaaaatt
     8941 ttactttttt gctgatgaaa aagtttacaa gttatttgtg aagatatgtt cttagtgttt
     9001 tgaaatagta tttgtatata ttcctgctta gttgagatag ttttgtatgg attttcatat
     9061 gtgtagagtt aaatgttagg tactaaagtt tatgttaaat taaatgttaa agcttatgtt
     9121 aaaaatttta ttaaatttaa tctgtaaata aaaaagttaa aagtccaata ttaacatttt
     9181 acttttaaac cattaaaatc tttattaaag ctaacaaagt tataagttat gagaaatttt
     9241 attaaagtta atacaaaaat taattttaaa gctaagaaat tttttattag attcaataaa
     9301 actaataaat atagtttagt caataatgta ttaaataaaa actttgttaa gtctataaaa
     9361 atatcttaaa ggaggtgtaa cttatgaaga taaaagtgga ggatatacca gttcaatttc
     9421 atgcaatggt agaaataatt ggaattgata agtttataga ggttgccaag ttgtatggag
     9481 gaacaaatac ttatatacct acgtataagg ggctttttag atatgctaga aatagggata
     9541 tagtaaaaca atttaatgga gtcaaccaca atgaattggc tattagatat aatatgtgtg
     9601 taagcaatat taagcgaata ctcaatgaaa atagtgttta aatataataa aatagtgttt
     9661 aaacataatg aaaatagcct tgttaaatgt aaaagtaaag acaaagaaga tgttttataa
     9721 agttttttta gacaaattaa ctaaatttac tacttattaa tttaaataca ttgtatattc
     9781 tataaaaaaa tttgttaaat actggagata tattgagaat acaaagaaaa tggtcgaaaa
     9841 tatttgttgg ctaaaaaata gataaaatga tacaattgct tgtataaagg ggaaaaataa
     9901 ataaataaac tatataaata aagaaatagc aattaatatg acataatata tttataaaat
     9961 taagaatata aatagatatt ttaagggatt agttgttaaa ttaggaaata ttaaaaaaaa
    10021 tatatattta tatttaaact attttgttat ttatataaaa atacttatct agttactagc
    10081 aattattagt agaaatgggg gaaatagaga tgaataaggg attttacaaa ttaaattcag
    10141 tggtattgaa ctttgatatt aagaatgatg ttaacaagat aagatttaat cattatataa
    10201 tgagaaaaga aaacatacaa agacttcaag gaactctgcc aaacggacaa ttttatatga
    10261 cagtgagaag agctgctaca gatttacaac tttctatttc tactataagt aggcttgtaa
    10321 aagagttttt ggatttaggg ataataagat tagtgtctaa gggtgtaaaa ggtaatcgtt
    10381 ctgtatatag ttacgtaagt atagagttta atggaagttt atttgatgat agtaaatata
    10441 tggaacttga ctgtgtatgt aatgatgaat ttattgataa tagtggcata gagtttgatt
    10501 gtgatagcaa agataattct tttaatggag atataaatgt agaaactgtg cattgcatta
    10561 atgagtattt ctctgatgat gatgtagagc ataattataa caatttccat aacaaagata
    10621 ctataaagga taaagccatt tctaatatta gcactatcaa aaaatatatt gatgaatctt
    10681 ttgatacaaa taaatcagaa aattctaact tacaacagga gtcaataaat ttcaacttta
    10741 atgatacatg caatgaaata gataaaagaa cgaataatag tatagaaaat aatcaaaata
    10801 aaaggcctat gagattgagt gacatcagtg ttttaagtga taaaggtatg acaaataaaa
    10861 agaattactt taatcataat catggtatac aaaaagggac taaatctgta acaaagaaaa
    10921 aagaatcctt aaataaattt aataaaaaaa atatacagca aagcattata aatatgctaa
    10981 ataaaaaatc aggtaagaat tttaaaatcg attctccaat aagcataaaa cttatcaatg
    11041 aaaggctaaa ggaaggctat gtcttagaag atttctacaa agttattgag gtaaaagtgg
    11101 ctaagtggaa aaataccata atggaaatgt atataagacc agaaactttg tttagctata
    11161 agtttgaatc ctatgtaaat gaaaacatat ctatgaaaag tcaaagtaat gttcacccat
    11221 gtaaagaagg caatagtaat gatagcagta attatataca ttctgattat acaacatatg
    11281 atggcagtgt gcgtgagaga aaaaaatatg agaatgtaag atactggaat cctatatgtg
    11341 aaatttaatt agtttaagaa tgtatttatg ataaataagg tattaataga gaatagtgag
    11401 ctatagcaaa tgatatatca atagttggta gtaagttata ttaagcaaga tattactatc
    11461 aggtagtgaa ttgtattg
//
LOCUS       DAEORM030000091        11143 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.097, whole genome shotgun sequence.
ACCESSION   DAEORM030000091 DAEORM030000000
VERSION     DAEORM030000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11143)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11143)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 11143)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11143
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.097"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            176..373
                     /locus_tag="KRH23_003527"
     CDS             176..373
                     /locus_tag="KRH23_003527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226797.1"
                     /translation="MVKSESDIIDTIHTGQVITDENGTQYFVCGKNRIKISEHFAAGG
                     RPIGDLIVDVVRHTAARAASS"
     gene            469..2091
                     /locus_tag="KRH23_003528"
     CDS             469..2091
                     /locus_tag="KRH23_003528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003019515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4368 domain-containing protein"
                     /protein_id="HHS5226798.1"
                     /translation="MKQPYNTTIYNTALYMRLSRDDESYGDSVSIETQRTILQQYARE
                     QGLHVVGEYVDDGWSGTNFERPSFQRMMDDVEAGKVNCIVTKDLSRFGREHVMMDYYL
                     EFLFPEKRVRYIAVAENEDTEKGLSDFVPFKNLFNEWFAKDTSRKVKTAFKAKFAAGQ
                     RISAYAPLGYKKHPEIKNKLIIDEETRWIVEKIFDLAIHGKGAASITRILIAEKVPTP
                     GFINFQRDGTFANIYAGAPEEKGYAWTIAQVKSIMKDETYIGHTIHYRETNISFKNKR
                     RIRKPQSEWVRVENTQEPIISEQVFRQVQEQIASRRRERKNGTTQIFAGLIKCADCGW
                     SLAYGENRQNSKPYGYYHCSKNGQGTRQCSMHYIRYDVLYAYVLSRLQYWSALVQHDE
                     EQLLKRLLNANDKGQAAARKKQAAELKKAEKRKAEVDTLFARMYEDWAAGRITEYNFN
                     MLSGKYQSEQAELEEKIEQLQSAIAAESQSAADAEKWIALMKECVNPTELTAELLNTL
                     IEKILVHEAVKNEDGSREQEVEIFYRFIGKID"
     gene            2150..3220
                     /locus_tag="KRH23_003529"
     CDS             2150..3220
                     /locus_tag="KRH23_003529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HHS5226799.1"
                     /translation="MPLLADFFNVSIDKLLNYKIDLSEEEVMKIYKELESGFARIEID
                     LSTEEPKEEFRQDLESVKKLSNMYIEKYPKSYLLKLRICSLYQMYSYKFGKSELNDRV
                     KETTNILEDIVRNTDDIQIKETALIILSNAYCMLEDYEKAELYLNMIHKSIGDTSVNL
                     AMIYLKQNRLEEAEILLQNKLFSNVFNISMDCKGIINVYKNQYKELKKKLENRNFNKN
                     AIEREMEYIKNKLLGYANLSLEIKKMLSEDKGAFFSMYMDYMELSLIFLFFNMKEEAK
                     KALYSLKEILEKYPIHENLDVSQMRFFDKVESKNLYTFNIYTNLLIVLNDDSYNELRE
                     EPIFKDVIEKILDMEKMLKNKE"
     gene            complement(3639..4043)
                     /locus_tag="KRH23_003530"
     CDS             complement(3639..4043)
                     /locus_tag="KRH23_003530"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: protein motif:HMM:NF012792.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HHS5226800.1"
                     /translation="MKNKEYQFNLIYDKNQFVGIILCWETDDFIYVEHFCIFPEMRNN
                     RYGQRALELLNKKGKTIILEIDLPIDEISIYRKAFYERVKYKTNNYEHIHPPYHEKFN
                     GHNLIVMSYPEKLSKMEYDKFNHYLRNNVMSF"
     gene            4515..5312
                     /locus_tag="KRH23_003531"
     CDS             4515..5312
                     /locus_tag="KRH23_003531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HHS5226801.1"
                     /translation="MEKREKRIIISSLLSVSILMGLVSIYSILNKEDIILTVKGQEQK
                     VSSFKKTVEELLDEQGVKYNFEDKINPSLDTELKDDMKIKVVKVTKSKKEEIEKIPFD
                     TKHVNDSNLLKGKSKVYQEGQEGEKKLVYNLTYHDGKLVKKVLSKEVISKEPTTKIIK
                     YGTKEKVLIASRGANIRGGKHMKVVATAYAGDTITSTGTTPRWGVIAVDPRVIPYGTK
                     VYIPKLGMTFVAEDCGGAIKGNRIDIFMNSEGKASNWGRKSIDIYLH"
     gene            5422..6012
                     /locus_tag="KRH23_003532"
     CDS             5422..6012
                     /locus_tag="KRH23_003532"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HHS5226802.1"
                     /translation="MKIVCLGDSLTYGFGVSRSNSWTNIVNKETRLEIVNKGINGDTT
                     SGMLARFNEDVVKNSPDIVFIMGGTNDFIAGAGNEIINSNIMAMVHQSYSKNIIPIIG
                     IPLKPDIPNVREDWSCFTDFNIVSQNLESYSYWIKKFCMTFNTNFVDFYSEYNKNMEL
                     EGHKKLYFDGLHPTKEGHRIMADIFINSINKYIEEL"
     gene            6078..7775
                     /locus_tag="KRH23_003533"
     CDS             6078..7775
                     /locus_tag="KRH23_003533"
                     /EC_number="5.4.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016868 - intramolecular
                     phosphotransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HHS5226803.1"
                     /translation="MDYTKTYEEWIKGSYFDEDTKLELENIKNNEKEIEDRFYKDLEF
                     GTAGLRGIIEAGTNRINKYTVRRATFGLANYILENTTKEETSRGVVIAHDNRHKSRQF
                     CIESANTLAACGIKAYIFDSLRTTPELSFAVRSLNAIAGIVITASHNPPEYNGYKVYW
                     EDGAQVMPEIANAITEKVNSIHDYSTIPTLTEANKNLVVLLEESQDTKFIEAVKSQII
                     RKDLVKNVGKSFKIVYTPLCGTGNVPIRRALKEVGFENIIVVPEEENPDPNFAGLDYP
                     NPEEKKALNRGILLAKEKGADLVIATDPDCDRVGVAVKTTTGEYALLTGNQIGGMLTH
                     YIIEGLKENNRLKENPTIIKTIVTSEFGADIAKANNVDVLNVLTGFKFIGEKIKLFEQ
                     NKNRSYVFGYEESYGYLVGTHARDKDGVVSSLLISEMVAFYYSKGMSLYDGLIELYKK
                     YGFFKEQTISLTLKGIEGVEKIKEIISYFRENQIDYINSIKVVDKKDYKNGIDNLPKS
                     DVLKYFLEDESWVAIRPSGTEPKLKFYIAVKGASDIEADKKIQGLKKYIDDMVEKLK"
     gene            7989..8828
                     /locus_tag="KRH23_003534"
     CDS             7989..8828
                     /locus_tag="KRH23_003534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HHS5226804.1"
                     /translation="MFGIDKKLIEYIIAKSNYSELSSKSAEVSFFLMLSIFPFLIFTI
                     SSIAYIPILHLNKYIALFRNMMPEGAFAVLSSIIVSAIDNRNLKFLAVSFVLTMWTFS
                     RAVKALIKGMNRAYKVKETRSFFKILSISFLFTIMLLVLIFLSMIFLVYGEKIGYFIF
                     NLVGLDEIFIKIWDILRYTVGIITIIVIFTLLYKYTPNKKLTIKESAPGAIFATFAWF
                     LVSFLYSYYTNYYANYEVIYGSIAEIIVLMTWMYFSSWSIVIGYEVNSRLYFRKIRHE
                     MLK"
     gene            9345..>11143
                     /locus_tag="KRH23_003535"
     CDS             9345..>11143
                     /locus_tag="KRH23_003535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HHS5226805.1"
                     /translation="MDTHNKYVNFIKNIPVPFLYCRIVKRQEDIEYRVEYISKGMGKV
                     LQLEEGICDKNILDVLPVFKSKKYFKELFSNEVDCIKRYIPTLKNWINIKKQIIGDSY
                     IILYFGKIVFDYRQIIDSFDKKEKVAYIKDEEGIYIDCSENLIPILNNNIKTTKDIFG
                     KNDIEVWGENTGKLFRDDYREGVSSKKRFLQNLFEYEETFFMVEKYFLYDEDELLGTI
                     GIVDNIIYSGYSNRNYNSKDLMKMIEHSIPENMFYKDVYGNYIGFNSGFLNLACMNKE
                     ELLGKNSYKISEEEALIDKIFESDKGVVENKKVVTFELNISMNDENKCIEITKRPFFD
                     SYGSVIGIIGTARDISRRKRLEEEMDKTRMEFFANLSHELRTPINLISSSLQVIEKKE
                     ADLIESNDTLKRNLGIIKQNGNRILRLVNNVIDFTKMQSGYLDFKPEESDIIAFIEEI
                     CMSVADFASQNNIQLTFDTEIEEFSMLFDSEKLERIILNLLSNGIKYNKKDGKINIFL
                     YVKDNVFNMKISDSGIGIPKEKIDKIFNRFEQIDNELSYRVKGSGIGLSLVKSLVELH
                     EGSISLKSQLGIGSEFIVSLPVRSKNNIEKYNH"
BASE COUNT         4299 a         1307 c         2088 g         3449 t
ORIGIN      
        1 acgatggaac gggcaaagct gaaaagcgaa ctggacaatt tacagcggct ggttgaccgt
       61 atcccgccgg aagtgctggc ggagctgaaa cggcagcagc gaacaagagg gaggtaaacg
      121 ctatgaacag aaattcaagc tgcatgatga aaaataatca tacggaggac actggatggt
      181 aaaaagcgaa agcgacatta ttgatacaat acacaccggg caggtcatta ctgacgagaa
      241 cggcacacag tattttgtat gtgggaaaaa ccgtatcaaa atctccgaac attttgccgc
      301 tggcggtcgt ccgattggcg atctgattgt ggatgtcgtc cggcacacgg cggcaagggc
      361 agcttcttcg tgacccatcg ttgatacacg cccacgctta tgatataatt gccatagagc
      421 aaaagtattg taagcgtggg ttgtttcttt agaaggagga tttttacggt gaaacaacct
      481 tacaatacta ccatttacaa cacggctctt tatatgcggt taagccgtga cgatgaaagc
      541 tatggtgaca gcgtaagcat tgaaacgcag cggacaatcc tgcaacagta cgcaagggag
      601 caggggcttc atgtggtcgg ggaatatgtg gacgatgggt ggagtgggac aaacttcgag
      661 cgtccgagtt tccagcgcat gatggacgat gtggaagccg gaaaagtaaa ctgcattgtc
      721 accaaagacc tgtcccgttt cgggcgggag catgtgatga tggactacta tctggaattt
      781 ctgttcccgg aaaaacgggt gcggtacatc gccgttgcgg agaatgagga cacagaaaag
      841 ggactgtccg attttgtgcc attcaaaaac ctgttcaacg aatggttcgc aaaggacacc
      901 agccgcaagg taaaaactgc tttcaaggca aagtttgccg ccggacagcg tatcagcgcc
      961 tatgctcccc tcgggtacaa gaagcacccg gaaatcaaga acaagctgat aatcgacgag
     1021 gaaacccgct ggatcgtgga gaagattttt gaccttgcta ttcacggcaa aggggcggcc
     1081 agcattacaa ggatattgat tgcggaaaaa gtaccgacgc cgggatttat caacttccag
     1141 cgtgacggga ctttcgccaa tatctatgct ggcgcaccag aggaaaaagg ctacgcatgg
     1201 acgatagcgc aggtcaaaag cattatgaaa gatgaaacct acatcggcca taccatccac
     1261 taccgggaga ccaatatttc ctttaagaac aagcggagga tacgcaagcc ccaaagcgaa
     1321 tgggtgcggg tggagaacac gcaggagccg attatcagcg aacaggtttt ccggcaggta
     1381 caggagcaga tcgcaagccg ccggagggag cgcaagaatg gcacgacaca gatttttgcg
     1441 gggctgataa agtgtgcgga ctgcggctgg tcgctggcct acggggagaa cagacagaac
     1501 agcaagccct atggctacta ccattgtagc aagaacgggc aaggcacacg ccaatgctcc
     1561 atgcactaca tccgctatga tgtgctttac gcctatgtcc tctcccgtct gcaatactgg
     1621 tcggcgctgg tacagcacga tgaagaacag cttttgaaac ggctgctgaa cgccaatgac
     1681 aaaggacagg ccgccgcaag aaaaaaacag gctgctgaac tgaaaaaagc ggagaagcgg
     1741 aaagccgagg tcgataccct gtttgcccgg atgtatgagg actgggcggc ggggcgtatc
     1801 acagaataca acttcaatat gctgtccggg aagtaccaaa gcgaacaggc ggaactggaa
     1861 gaaaagattg aacagcttca atctgctatt gccgctgaaa gccagagtgc cgcagacgca
     1921 gaaaaatgga ttgccttgat gaaagagtgc gtcaatccca cggaactcac cgctgaactc
     1981 ttgaacacgc tgattgaaaa aatccttgtc catgaggcgg tcaagaacga ggacggaagc
     2041 cgggaacagg aggtagaaat cttctaccgc ttcatcggca aaattgattg aatgacacca
     2101 atatctttaa gtatgtgata ccggaaattc ttacccagat atagaattat tgcctttatt
     2161 agcagacttt tttaatgtgt ctattgataa gcttttaaat tacaagattg atttaagtga
     2221 agaagaagta atgaaaattt ataaagaatt agaatcaggc tttgctagaa ttgaaattga
     2281 tttatcaaca gaagaaccaa aagaagaatt tagacaagac ttagaatctg taaaaaagct
     2341 ttccaatatg tatatagaga agtatcctaa aagctattta ttgaagctaa ggatatgttc
     2401 gctgtatcag atgtattcat ataaatttgg taagagtgaa cttaatgaca gagtaaaaga
     2461 aacaacgaat attcttgaag atatagtgag aaatacagat gatatccaaa taaaagaaac
     2521 agctcttatt atattatcaa acgcatattg tatgttggag gattatgaaa aggcagagtt
     2581 gtatttaaat atgatacata agtcaatagg ggatacaagt gttaatttag ctatgatata
     2641 tttaaagcaa aatagacttg aagaagcaga aatattgctt caaaataaat tgtttagtaa
     2701 tgtatttaat ataagcatgg attgtaaggg aataattaat gtatacaaaa atcaatacaa
     2761 ggaattaaag aaaaaattgg agaatagaaa ttttaataaa aatgcaattg agagagaaat
     2821 ggagtatata aaaaataagt tgctggggta tgcaaatctt tctttagaaa taaaaaaaat
     2881 gctcagtgaa gataaaggtg cattttttag tatgtatatg gattatatgg aattatctct
     2941 aattttttta ttttttaaca tgaaagaaga agcaaaaaaa gccttatata gtctaaaaga
     3001 aatattagaa aaatatccta tacatgaaaa tttggatgta agtcaaatga gattttttga
     3061 taaggtagag tctaaaaatt tatatacttt taatatatat acaaacttgt taattgtact
     3121 taatgatgat agttataatg agcttagaga agaaccaatt tttaaggatg taattgaaaa
     3181 gattttagat atggaaaaaa tgttgaaaaa taaagaataa gtaaaaattt aatataggac
     3241 ttaaagatta atcaaattaa aagaaagtgt ttcaaaataa aaatttgaat cacttttttg
     3301 ttgatcttaa acagttattt agaaaaatag aggtttcaaa atataaatct gaattatctg
     3361 tattattaca caaaaataga aacctaaatt tataaaaata gaataaagtt tgttatataa
     3421 aatgtaattt tgtctataaa atctcacctg ttttcttaac tttaagcgtg aaaaagagga
     3481 tgtatcatga attttttagt tcatgatgca tccttctttg tatgaaatcc aatatatctt
     3541 tattatttaa acaatggaaa agagtcttat ttctattttg agacatctct tttatttaat
     3601 tatgaagttt tatacagttc aataaatagg aattatattt agaaactcat gacattattt
     3661 cttagatagt gattaaattt atcatattcc attttagata acttttctgg gtaagacatt
     3721 acaatcaggt tatgcccatt aaatttttca tggtatggtg gatgaatgtg ttcataatta
     3781 tttgtcttat attttactct ttcatagaac gccttgcgat aaattgaaat ctcatcaatt
     3841 ggaaggtcaa tttctaaaat aatagttttc cctttcttat ttaaaagctc taacgctctt
     3901 tgtccatatc tattattgcg catttctgga aaaatgcaga aatgttctac atagataaag
     3961 tcatctgttt cccaacataa aattatgccg acaaactggt ttttatcata aattaaattg
     4021 aattgatatt ctttattttt caaaatttct tcttgcaaag aagatttttt tgttcatgaa
     4081 atgggaaact aattttatat aattccatag ccttgtaata taatttattt tcactggttc
     4141 ttaaccgttc aaatttcact ttactcctcc taatcactaa aattccaatt tatttatgag
     4201 ttcattttac catagtcagt atttgcatac aatgtgtttt aagttgagtg tcatttcttt
     4261 cttttattta tgtttatatc tcatagacta agagataatt acttaagaca taactaaaaa
     4321 ctattatatt aagctttgat aatctaaaaa cagtatattt atggactttt ctaggtctaa
     4381 aagtaatctt aataatttta gaagttacaa aaaagttaca taaatttgga aagctataat
     4441 atacatatat aatataaggt taaaactgta atgaataata ttaatttaaa atttgaacat
     4501 ggaaggagat tattatggag aaaagagaaa agaggataat aatatcatct ttattaagtg
     4561 tatcaatttt aatgggtttg gtaagtatat attctatatt aaataaagaa gacataattt
     4621 taactgttaa gggtcaagag caaaaagtat cttcctttaa gaaaacagtt gaggaacttt
     4681 tggatgaaca gggtgtaaag tataattttg aagataagat taatccaagt ttagatacag
     4741 aactaaaaga tgatatgaaa ataaaagttg ttaaggtaac taaaagtaaa aaagaagaga
     4801 ttgaaaaaat tccatttgat acaaagcatg taaatgatag taatttgtta aaaggaaaat
     4861 ctaaagttta tcaagaaggt caagaaggag aaaaaaaact agtctataat ttaacttacc
     4921 atgatggaaa gttagtcaaa aaagtcttat caaaagaagt aatatctaag gagccaacta
     4981 caaaaattat aaaatatgga actaaagaaa aagtactaat agcatcaaga ggagcaaata
     5041 taagaggagg caaacatatg aaagtggttg ccactgcata tgcaggagat acaataacat
     5101 ctactggtac aactccaaga tggggtgtta ttgcagttga cccacgtgta ataccatatg
     5161 gaacaaaagt atatatacct aaactgggta tgacttttgt agcagaagat tgtggaggtg
     5221 caattaaagg taatagaata gacattttta tgaacagtga aggaaaagct tcaaattggg
     5281 gaaggaaaag tatagatata tatctacatt aaattagtga atagaataac tttacttgaa
     5341 ggacaaaaaa gtataaaata tgaattaact aaactgttag attattctta aaacataaaa
     5401 atatatctaa ggagggataa gatgaaaata gtctgcttag gagacagttt aacgtatgga
     5461 tttggagtat cacgaagtaa ttcatggaca aacattgtaa ataaagagac tcgattagaa
     5521 atagtaaata agggtataaa tggtgataca acaagtggta tgttagctag gtttaatgaa
     5581 gatgttgtaa aaaactctcc tgatatagtt tttataatgg gtggcaccaa tgattttatt
     5641 gctggtgcgg gaaatgaaat tattaattct aatataatgg ctatggtgca tcagtcatat
     5701 tcaaaaaata ttatacctat aataggtata ccattaaaac cagatattcc aaatgttagg
     5761 gaagattgga gttgttttac tgattttaat atagtatctc aaaacttaga atcatatagt
     5821 tattggataa aaaaattttg tatgacattt aatactaatt tcgtagattt ttattcagaa
     5881 tataataaaa atatggaact agaaggacat aaaaaattat attttgatgg gttacatcca
     5941 accaaagagg gtcatagaat aatggcagac atttttatta attcaattaa taagtatata
     6001 gaagagttat agattacatt aaaatgcttg tttatgcgtc agttgcaata aatacataca
     6061 gtagagaggg gtttattatg gattatacta aaacttatga agagtggata aagggttcat
     6121 attttgatga agatacaaag ctagagttgg agaatataaa aaataatgaa aaagaaatag
     6181 aggatagatt ctataaggat ttagaatttg ggactgcggg tcttagagga ataattgaag
     6241 caggaacgaa tagaataaat aagtacacag ttagaagagc tacttttgga ttggcaaact
     6301 atatattaga aaacacaaca aaagaagaaa caagtagagg agtagtaata gctcatgata
     6361 atagacacaa gtctagacaa ttctgtatag aatctgcaaa tactttggca gcatgtggta
     6421 taaaagcata tatatttgat agtttgagaa ctactccaga attatctttt gctgttagaa
     6481 gcttaaatgc aatcgctggt atagtcataa cagcaagcca taatcctcca gaatataatg
     6541 gatataaggt atactgggaa gatggagcac aagttatgcc agagattgca aatgcaataa
     6601 cagagaaagt aaatagtata catgattata gtacaatacc aaccttaacg gaagctaata
     6661 aaaatttggt agttttgttg gaagaatcac aagatactaa atttatagaa gcagtaaaaa
     6721 gccaaattat aagaaaagat ttagttaaaa atgtaggtaa aagctttaag atagtttata
     6781 cacctctttg tggaacaggg aatgttccaa taagaagagc attgaaagaa gttggttttg
     6841 aaaatataat tgtagttcca gaagaagaaa atccagaccc aaattttgca gggcttgatt
     6901 atccaaatcc agaagagaaa aaagctttaa atagaggtat attactcgca aaagaaaaag
     6961 gagcagacct tgtaatagca actgacccag attgtgatag agtaggtgta gcagtaaaaa
     7021 ctactacagg tgagtatgct ttacttacag gaaatcaaat tggtggtatg ctgacacatt
     7081 atataataga aggattaaaa gaaaataata gattaaaaga aaatcctaca ataataaaaa
     7141 ccatagttac atcagaattt ggagcagata tagctaaagc aaataatgtt gatgtattaa
     7201 atgttcttac aggttttaaa tttattggtg aaaaaataaa attatttgaa caaaataaaa
     7261 atagaagtta tgtatttgga tatgaagaaa gttatggtta cttagttggg actcatgcta
     7321 gagataaaga tggtgtagtt tcttcattgt taatatctga aatggtagca ttttactatt
     7381 caaaaggtat gagtttatat gatggcttaa tagaacttta taaaaagtat ggatttttta
     7441 aagaacagac tatatctttg actttaaaag gtatagaagg tgtagaaaag ataaaagaaa
     7501 taatatctta ttttagagaa aatcaaattg attatataaa tagtattaaa gtagttgata
     7561 aaaaagatta taaaaatggt atagataatc ttcctaaatc tgatgtttta aaatactttt
     7621 tggaagatga atcttgggta gctataagac catctggaac agaaccaaaa cttaaatttt
     7681 acatagctgt aaaaggagct agtgatattg aagcagataa aaagattcaa ggtttgaaaa
     7741 agtatataga tgacatggtc gaaaaattaa aataaaatat tattatttta taagataatt
     7801 ttgtaataat atttatttag ctgaaaatta taatttactt tcattgagta gaatatggaa
     7861 atgttagtag aattgttatt ttcagctttt atttgtgtta tttttactta aataattata
     7921 ttatagaatg aatctgagta taattaatat tgtataatga aattaatttg atagaaaagg
     7981 ggatatttat gtttggtata gataagaaat tgattgaata tataattgca aaatccaatt
     8041 acagtgaatt aagttcaaag tcagcagaag tatctttctt cttaatgttg tccatatttc
     8101 cttttttaat atttacaata agttctatag cttatatacc gattcttcat ttaaataagt
     8161 atatagcttt gtttagaaat atgatgccag aaggtgcttt tgctgtgtta tcttcaatca
     8221 tagtttctgc aatagacaat agaaacctga aatttttagc agtcagtttt gtacttacta
     8281 tgtggacatt ttcaagagca gtaaaagctc ttattaaagg aatgaataga gcctataaag
     8341 ttaaagaaac taggtctttt tttaaaattt tatctatatc atttttattt acaataatgc
     8401 ttttggtcct tattttttta tctatgatat ttttagttta cggggaaaaa ataggttatt
     8461 ttatttttaa tcttgtagga ttggatgaga tatttataaa aatatgggat attctaagat
     8521 acactgtagg tataataaca ataatagtga tatttacact tttatataaa tacactccaa
     8581 ataaaaagtt aactattaaa gaatctgcgc caggtgctat ttttgctact tttgcttggt
     8641 ttttagtatc atttttatat tcttattata caaattacta tgctaactat gaagtaatct
     8701 atggaagtat agctgaaata attgtactta tgacctggat gtattttagt agttggtcta
     8761 tcgttattgg ctatgaggta aattcaagat tgtattttag aaagataaga catgaaatgt
     8821 taaagtaaag tatttaaaat aaaagagagt atttagtatt ataaatgtaa ttgaattaat
     8881 aaagaaatat tgacatttaa gttaaaaagt ctagaatttt tctgggcttt ttttattttt
     8941 agtataactt gacaaatttt atttaatggg atagttttaa tttataatca tctttaaaaa
     9001 gatgactatt gataagtaag agataaaatt ggtaagtatc aaaaaatata ctaaataaaa
     9061 attatagtcc taatgagtta atttctgtat tttcaaataa tgcagtattt agtcatgtgt
     9121 ttttatatgt gcctgtattt ctaattacca atatattaga ataagctact gtaattaggt
     9181 ttagaaaaaa gcgacataaa taattataaa caaataataa attacataaa attaaattta
     9241 ttcacaagta tatcttataa aatatgttat aattaataga aaattgtcat ataattaatt
     9301 aagtagtatt attataaata acattgaaag gtagtggtta gaatatggat acccataata
     9361 aatatgtaaa ttttataaaa aatatacctg tacctttttt atattgtaga attgtaaaga
     9421 gacaagaaga tatagaatat cgagtagaat atataagtaa gggtatgggc aaagtattac
     9481 aattagaaga aggtatttgt gataaaaata tattagatgt attgcctgta tttaagtcta
     9541 aaaaatattt caaagagttg ttctcaaatg aagtggattg tataaaaagg tacattccga
     9601 cacttaaaaa ctggataaat ataaaaaaac agataatagg ggattcatac ataattttgt
     9661 attttggtaa aattgtattt gattatagac agataatcga ttcctttgat aaaaaggaaa
     9721 aagtagctta tattaaagac gaagaaggca tatatataga ttgtagtgaa aatttaatac
     9781 caatattaaa taacaacatt aaaacaacaa aagatatctt tggtaaaaat gatatagaag
     9841 tatggggaga gaatacagga aaattattta gagatgatta tagagaagga gtatctagta
     9901 aaaaaagatt tttacaaaat ctttttgaat atgaagaaac attttttatg gttgaaaaat
     9961 attttttgta tgatgaagac gaacttttag gtactatagg gatagtagac aatataatat
    10021 atagtggtta cagtaataga aattataact caaaagattt aatgaagatg atagaacact
    10081 caattccaga gaatatgttt tataaagatg tgtatggaaa ttatattgga tttaattcag
    10141 gttttttgaa tttagcttgt atgaataaag aagaattatt agggaagaat agttataaaa
    10201 tatcagaaga agaagcttta atagataaga tatttgaaag tgataagggt gtagttgaaa
    10261 ataaaaaagt agttacattt gagttaaata taagtatgaa tgatgaaaac aagtgtattg
    10321 agattacaaa aaggccgttt tttgatagct atggaagtgt tattggaata attggaacag
    10381 caagggatat aagtagaaga aaaagattag aagaggaaat ggataaaact aggatggaat
    10441 tttttgcaaa tttatcccat gaacttagaa cgcctataaa tttaatatca tcttcattac
    10501 aagtgataga aaaaaaagaa gcagatttaa tagaatcaaa tgatacttta aaaagaaatc
    10561 taggtataat aaaacaaaat ggaaatagaa tattgaggtt agtaaataat gttatagact
    10621 ttacaaaaat gcaatcagga tatttagatt ttaaaccaga agaatctgat ataattgcat
    10681 ttatagagga gatatgtatg tctgtagctg attttgcaag ccaaaataat atacaactta
    10741 catttgatac agaaatagaa gaattttcaa tgttatttga ttcagaaaaa ttggaaagaa
    10801 taatattaaa tttactttct aatggaatta agtacaataa gaaagatgga aaaataaata
    10861 tatttttata tgtgaaagat aatgtattta atatgaaaat atctgatagt ggtataggta
    10921 taccaaaaga aaaaatagat aaaatattta ataggtttga acagattgac aatgaacttt
    10981 cttacagagt taaaggaagt ggtattggac tttcattagt gaaatctttg gttgagttgc
    11041 atgagggaag tatatcttta aaaagtcaac ttggtattgg aagtgaattt atagtttcat
    11101 tgcctgttag aagtaaaaat aatattgaaa aatataatca taa
//
LOCUS       DAEORM030000092        10640 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.098, whole genome shotgun sequence.
ACCESSION   DAEORM030000092 DAEORM030000000
VERSION     DAEORM030000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10640)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10640)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 10640)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10640
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.098"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            122..1282
                     /locus_tag="KRH23_003536"
     CDS             122..1282
                     /locus_tag="KRH23_003536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF819 domain-containing protein"
                     /protein_id="HHS5226806.1"
                     /translation="MIETGFVYCSFLVVFVGVIFFMVDKLKWKVFDVINPMLLIYLGS
                     AILGSFGLFAQNEDVGTYQNIITVNFLPLMLVFLLIQCDLRKILKMGPKMLLSFFCAT
                     FTFMLGFVIAFIIFKNSMGADSWKILGAASGSWIGGSSNMIAAANALGVAEEGLSYAI
                     LMGSIGYTVWMSVCLMSVKFGPKFNKWTKCDTSFIDEVTSKLEKENKDNTAPTFVELM
                     ILLSVGFGVASFAQIVSKILPTSGILNETMWVVLVASTVSILLGMTKISKLKGSTLVG
                     NVFMYLLLAATGSKANFFGLSEAPVYIMFGLVVVLVHAISFIGLAKLFKLDLFTCEVG
                     SIANIGGVTTAPMIAGVHNPVLIPVGVLMGLLGNIIGTYCALMVTQILHMLA"
     gene            1624..1785
                     /locus_tag="KRH23_003537"
     CDS             1624..1785
                     /locus_tag="KRH23_003537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226807.1"
                     /translation="MIIPSRRIQDITLTNLKNGEVTLIELDEIYKKMGFLFVVSEGKL
                     KKIKKENHH"
     gene            1978..2607
                     /locus_tag="KRH23_003538"
     CDS             1978..2607
                     /locus_tag="KRH23_003538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HHS5226808.1"
                     /translation="MKIVTYNIHKGMDSNNRLTLTKMGLYLKQLDCDVICLQEVLYPQ
                     FLALKAVLNMDGVFATNVKKVNMIYGICTFTTSKMLNSNHFFLTSKKEQRGALCITID
                     AYGRIINVINTHLGLDRQERAKQLDEIIDYRNRLVGIVILCGDFNEKNVFLSMFNDMA
                     ISLNKSYLPTFEKSNSRIDYIFVNKNTELKEYTVEKIYLSDHYPVIGYI"
     gene            2846..4105
                     /locus_tag="KRH23_003539"
     CDS             2846..4105
                     /locus_tag="KRH23_003539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanW family protein"
                     /protein_id="HHS5226809.1"
                     /translation="MGRRTTRVSRLGKEKKRSVLIVLAALVLIMGGFTYFFNSKFLYN
                     GKIAKNVYIEGVNVSDMTKAEALKAITDKYTPEDLNLTYDGKKYTISPKDIDLKYDTE
                     DVVKDAYESTKKGSYFQNLKKYIDIRVNKANMKIKAEYDEAKLSSKVSSIADSINVKM
                     KNASISVGSGGLSYTDSVVGREFDLAANKESIYNMIKNKEHKTLELKVNLQKPDITTE
                     QVKTVNSVIGQYSTTYSQAVEGRSYNVGLSARKTSDVLLMPGEEFSYNKLTGPSNKAN
                     GYKDAPVIVYGKLEQSAGGGVCQTSSTVYNAALLSGMEITQVTNHSSASTYVPKGRDA
                     TVSDGGLNLKFKNPYKHPVYIKNYAGGGSVSSVIYGNSGDKPNISIEVKQTGQNKYST
                     YRIFKDSNGKVIKKEHISNSSYKELKK"
     gene            4375..5358
                     /locus_tag="KRH23_003540"
     CDS             4375..5358
                     /locus_tag="KRH23_003540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004672 - protein kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="protein kinase domain-containing protein"
                     /protein_id="HHS5226810.1"
                     /translation="MTWLNFIGNRYEVVNSDDVLEINKIYKARDVFYRKNVLIKVIKH
                     NNYICEDFVSNLIDESTALDEINSPYILKIIDVGIHCTEETTLYYVVSEDFNGIGLDE
                     LILGNYLHLEAIVNIMIQVLKALEMIHRNHSYHGSLKSSSIIVDTEYNIKICDFGITK
                     ANNGVNTRSYGNRRYLCPHQLCINYTDKESDFFATGLILFESIFKKLPFGESNSEEKM
                     LQSIDKGLDWNSIKAINGNTELINVIKRLLGRNNKYTRANDIIIDLSKVMYEKAYIEV
                     EDEKEEEQKQDKVIQVKKEYKSKMRKKLHKKLVVAGLAIVMISMIIISSII"
     gene            5604..6671
                     /locus_tag="KRH23_003541"
     CDS             5604..6671
                     /locus_tag="KRH23_003541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008452 - RNA ligase activity [Evidence
                     IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA ligase RtcB family protein"
                     /protein_id="HHS5226811.1"
                     /translation="MSNIKIIASNKCWIEDIARKQLEDISKLNGILRVVGLPDLHAGK
                     IPVGLAVETKNIIYPHIIGNDIGCGMTLFKTGVLKKKFKKDKWIKSLSKIKDLSDIEI
                     KNTYKEECPILNLGTIGSGNHFVEIQCISEIYNKEQFEQLKFSSDDIMMLVHCGSRNY
                     GEDILKKFYDKDGLEVESEKAIDYIKKHDNALMWAERNREAISKKIMQSIGTSGYVET
                     IFSINHNFIEKREDKFIHRKGAVSSERGAVIIPGSRGSLSYIVMPTENTEISLYSLSH
                     GAGRKWSRSVCKSRLKSKYSKDTIKQTKFKSQIICNDVNLLFQEAPEAYKNIEQIIES
                     LIEYELIQVVATMKPLITYKG"
     gene            7205..9115
                     /locus_tag="KRH23_003542"
     CDS             7205..9115
                     /locus_tag="KRH23_003542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006259 - DNA metabolic process [Evidence
                     IEA];
                     GO_process: GO:0045910 - negative regulation of DNA
                     recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HHS5226812.1"
                     /translation="MNSNTFERLQLNEVKELIKIHCVSSLGKNLIDKLTPSGNIGVVR
                     RKLAENKEARKIIENSNHIPLEGLFNAGSTIDKIEKGMIIEPVELVNIEDFLRGCRKM
                     KAFMLEKEFYSPTLSSYALNITECKSIEDEINYCIKSNKVDSNASKELKKIRRNIEIT
                     EGKIKDRLNKFITSTVNKKYIQEFIISKRNDRYVIPIKSSYKNEVNGTILDTSSKGNT
                     VFIEPISVSNLSTELTMLKADETIEEYKILSYLTELIFEKISQIKLNIEILSEYDMVF
                     AKAKYSQKIKGITPKINNNGYIKIIKGKHPLLTGDAVPLDFEIGKNYRSLIITGPNAG
                     GKTVTLKTVGLLTLMVQCGFDISAKEGSEFSVFEKVFVDIGDNQSIENALSTFSSHIK
                     NIAEIMSLSNNSTLVLFDEIGSGTEPNEGAGLAISLLEEFYKMGCITIASTHYGEIKK
                     FATLHPEFENAGMMFDKETLEPLYKLTIGKSEDSNALFISKKMGIKNRVLDRAKEYVI
                     DRNYNLDLVKRSKLQSNIEDKNSSEVILNYTDYNVGDKVKLLDEDDFGIVYKPMDKFN
                     NVEVLFNDNFISVNIKRLQLSIKASELYPEGYDLDVLFTSFKERKLEKDIQRGSKKAL
                     KKIQKEIRENRK"
     gene            complement(9178..9801)
                     /gene="ytaF"
                     /locus_tag="KRH23_003543"
     CDS             complement(9178..9801)
                     /gene="ytaF"
                     /locus_tag="KRH23_003543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation membrane protein YtaF"
                     /protein_id="HHS5226813.1"
                     /translation="MIESILLVTSLCIDAFVTSFGYGVNKVKVPLYSNIIISVVCSAI
                     LAISLFAGTIVRDFLPQNITMLICFFILFLLGSARLIESFFKSYFKKKSIHSKNYNFN
                     MLDLKLNFNVSIEPDVLDTSKSKVLKSAEAFTLALALSLDGLAIGFGSGLVGVNYIQV
                     ILFSLISNIIAVLLGCLLGNMFVKNVNLNLSWLSGLILLVIGFMKIC"
     gene            9989..10633
                     /locus_tag="KRH23_003544"
     CDS             9989..10633
                     /locus_tag="KRH23_003544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHS5226814.1"
                     /translation="MEQHSKVGNFGDLLKVLLDEKELSMGELSKKSGIDKSTISRIAN
                     NKQKPNINHLEKMAIHLNINLEELLKASGYEFRNSNNQIFNADSDFSNFDDILGFANL
                     INDKNFNGNIEKELSKCKLYVQTDEGKKLLFDNFNKKIDSIEKQGQFTDRLRQMYADF
                     CTDGLTIKKYLLIGSMLLYFVISTDVIPDFVFPIGFMDDLVALNIVTKLLKNDK"
BASE COUNT         4357 a         1054 c         1744 g         3485 t
ORIGIN      
        1 atgtatttaa ttagcatgat atagataaaa gtatttattt taattgtcta ttatctgaaa
       61 aagtctttac ttagaaatca taaaaatcaa attaattagg aaaagaaagg gtgtgtataa
      121 tgtgattgag actggatttg tatattgtag tttcttggtt gtattcgtag gtgtaatttt
      181 ttttatggtt gataaattga aatggaaggt atttgatgtt attaatccaa tgcttttaat
      241 atacttaggt tcagctatac ttggatcatt tggtttattt gcacagaatg aagatgttgg
      301 aacgtatcaa aacataataa cagtgaactt ccttccatta atgttagtgt ttttgttaat
      361 tcaatgtgat ttaagaaaaa tattaaagat ggggcctaaa atgttattat catttttctg
      421 tgctacattt acatttatgc ttggatttgt tatagcattc ataattttta aaaattcaat
      481 gggtgcagat tcatggaaaa ttcttggggc agcatctggt tcatggatag gtggctcatc
      541 aaatatgatt gcagcagcta atgctctagg agttgcagaa gaaggactta gttatgcaat
      601 acttatgggt tctataggat atacagtatg gatgtctgtt tgtctaatgt ctgtgaaatt
      661 tggacctaaa tttaacaaat ggacaaagtg cgatacaagt tttatagatg aggttacatc
      721 aaaacttgaa aaagaaaata aagataatac agcacctacg tttgtagaac ttatgatttt
      781 actttctgtt gggtttggag ttgcgtcttt tgcacaaatt gtatccaaga tacttccaac
      841 ttcaggtata cttaatgaaa ctatgtgggt agtacttgtt gcatctacag tatcaatatt
      901 attgggtatg acaaaaatat caaagcttaa agggagtaca ctggtaggaa atgtgtttat
      961 gtatttactc cttgcagcta caggtagtaa agcaaatttc tttggattgt cagaagcacc
     1021 tgtttacata atgtttggat tggtagtagt ccttgtacat gctatttcat ttatagggct
     1081 tgctaaacta tttaaacttg atttatttac ttgtgaagta ggaagtatag ctaatatagg
     1141 aggagtaact acagctccaa tgattgctgg ggttcacaat cctgtattaa taccagtagg
     1201 tgtacttatg gggcttctag gaaatattat agggacttat tgtgctctta tggtaactca
     1261 aatattacat atgttagctt aataaaaata tggtataaaa ttaataattt aaataagaaa
     1321 agtcatttca atttaagtag aagcttttac tgaaatggct tttttgtttg acaagataat
     1381 ctatttcaag aagatgtttt gacatattta gtgtataata ttgtaaaatt tactaaaaac
     1441 gagatatatt taatttttat attgaatcga acgtctgtat gatgtataat aaatatacag
     1501 aacgaatgtt tgcagaacgg gtgttttttg aatttatttt aataatttat gaatatatat
     1561 cagaatgcat aaatatattt aaatataaag attaaaaaga atttaaagga gtgttgataa
     1621 cttatgataa ttccatcaag aagaatacaa gatataacat taacaaattt aaaaaatggt
     1681 gaagtaactt taattgaatt ggatgaaata tacaagaaga tgggattttt atttgttgtt
     1741 agtgaaggca aattgaaaaa gataaaaaag gagaatcatc attagaaatg aatgaaataa
     1801 taaatattat aatagtttat aaaacctaac ttatgtagaa tataaatact taagttaggt
     1861 ttttttgtga taaagtttat aagtactcaa ttttataaga taaataatgg tcttaagtga
     1921 aaagtaaata agtttaaatt ttagtaagta ttatattgca taagaggtga tattattatg
     1981 aaaatagtaa cctacaatat tcataaaggt atggattcaa ataatagatt aactctaact
     2041 aaaatggggt tatatttaaa acaattggat tgtgatgtaa tttgtttgca agaagtatta
     2101 tatcctcaat ttttagcttt aaaagctgtt ttaaatatgg atggtgtctt tgctacaaat
     2161 gtaaaaaaag taaatatgat atatggtatt tgtacattta caacatctaa aatgttaaac
     2221 agtaatcatt ttttcttaac tagcaaaaaa gaacaacggg gagctctttg tataactata
     2281 gatgcatatg gaagaattat aaatgtaata aatactcact tgggacttga taggcaggag
     2341 agagcaaaac agttagacga aataatagac tataggaaca gattagtggg gatagttatt
     2401 ttatgtggtg attttaatga gaaaaatgtc tttttaagta tgtttaatga tatggctatt
     2461 tcactaaaca agtcttactt accaacattt gaaaaatcaa actctagaat agattacatt
     2521 tttgttaata aaaatactga actaaaagaa tacacagtag aaaaaattta cctgtcagac
     2581 cattatcctg taataggtta catttaaatt tcaatataaa tgaaattagt tgttataaaa
     2641 taaacaattt tttgttaaga aatagtaaaa gaaatataat aaaaaatatc aaaaataaaa
     2701 ctaattataa gacataaatt tacaataaag ttacatttga ttaaattcct tgtttaacaa
     2761 aagctattca aatataatct aaggtagttt tgaaatggga actctattat gcaaatttaa
     2821 gctagtgtta aaatgaggtg aagttatggg cagaagaaca acaagagttt caagattagg
     2881 taaagaaaaa aaacgaagtg ttttaattgt attggcagct ttagttctaa taatgggtgg
     2941 atttacttat ttttttaaca gtaaatttct gtacaatggg aaaatcgcta aaaatgtata
     3001 tatagaagga gtaaatgtat ctgatatgac taaagcagag gcattaaaag ctataacaga
     3061 taagtatact ccagaagact taaatcttac ttatgatggg aaaaaatata caatatcacc
     3121 aaaagatatt gatttaaaat atgatacaga agatgttgta aaagatgctt atgaaagtac
     3181 aaaaaaaggg tcctattttc aaaacttaaa aaaatatatt gatataagag tgaataaggc
     3241 aaatatgaag ataaaagctg aatatgatga ggcaaaactt agttccaaag tgtcttctat
     3301 agcagatagt atcaatgtta agatgaaaaa tgcttctatt agtgttggaa gtggtggact
     3361 aagttataca gactctgttg taggtagaga atttgatttg gcagcaaata aagagtctat
     3421 atataatatg ataaaaaata aagagcataa aactttagaa cttaaagtaa atcttcaaaa
     3481 accagatata acaactgaac aagtaaaaac tgtaaattct gttataggtc aatattcaac
     3541 tacttattca caagctgtag agggtaggtc atataatgta ggattatcag caagaaaaac
     3601 tagtgatgta ttattaatgc caggtgaaga attttcatac aataaactta caggacctag
     3661 taataaagca aatggttaca aagatgcacc tgttatagtt tatggtaagc tagaacaatc
     3721 agcaggagga ggtgtttgtc aaacatcttc aacagtttat aatgcggctc ttctttcggg
     3781 tatggagata actcaagtta caaatcattc atctgcatct acttatgtgc ctaaagggag
     3841 agatgctact gtgagcgatg gaggattaaa cttaaagttt aaaaatccat ataagcatcc
     3901 tgtatatatt aaaaattatg caggtggagg aagtgtatca tcagtaatct atggtaattc
     3961 tggtgacaaa ccaaatatat ctatagaggt aaaacaaact ggtcagaata aatattctac
     4021 atatcgaata tttaaagatt caaatggaaa ggtcataaaa aaagaacata tatcaaatag
     4081 ttcttataaa gaattaaaaa aatagataat tttttagaga aatatttgta atataaaagg
     4141 gagtgtctca aaatgaactt tttagtttag agacactctt tttatgtgaa atcaaatata
     4201 ttttcatcat ttcaacaata caaaagaagc atatctctat tttgagacag ccttttttgt
     4261 aaaaattaac actattagtt cttgttttaa tattacaatc attaatatat agaaaatatt
     4321 cctatatatt ggtataattg taaatagatt tagttatata aaatgtatga ggaggtgaca
     4381 tggttgaatt ttataggcaa tagatatgag gtagtaaatt ctgacgacgt tttagaaatt
     4441 aacaaaatct ataaagctag agatgttttt tacaggaaaa atgtgttaat aaaagttata
     4501 aagcacaata attatatctg tgaagatttt gtttcaaatt taattgatga aagtactgct
     4561 ttagatgaga taaactctcc ttatatacta aaaataatag atgttgggat tcactgtaca
     4621 gaagaaacaa cattatatta tgttgtaagt gaagacttta atggtatcgg actagatgaa
     4681 ttaattctag gtaattatct tcatttagaa gcaattgtaa acataatgat acaagtttta
     4741 aaagctttag aaatgataca taggaatcat tcatatcatg gtagtttaaa atcgagtagt
     4801 ataatagtag atacagaata caatataaaa atttgtgatt ttggaattac aaaagcaaat
     4861 aatggggtta atacaagaag ctatggaaac aggagatatt tatgcccaca tcaactatgt
     4921 ataaattata ctgataaaga aagtgatttt tttgcaacag gtcttattct atttgaatct
     4981 atatttaaaa aattgccttt tggagaatca aattcagaag aaaaaatgct acaatctatt
     5041 gataagggat tagattggaa tagtataaaa gcaattaatg gaaatactga acttataaat
     5101 gttataaaaa ggcttcttgg aagaaataat aagtatacca gagccaatga tattattatt
     5161 gatttaagta aagtaatgta tgaaaaagca tatatagaag ttgaagatga gaaagaagaa
     5221 gagcagaaac aagacaaagt tatacaagtt aaaaaagaat ataaaagtaa aatgagaaaa
     5281 aaattacata aaaaacttgt tgttgccggt ctagctatag tcatgatttc aatgattatt
     5341 attagttcca taatataaaa attgtatatt aagtatttta aaatcaatgt ctataaagga
     5401 tatacataga aattttagtg tagtcttaaa ttatgaaagg aagtggttat tatgttaaca
     5461 aaaaataatg aggtattaaa cgtctaggag tattttaaca aatagccacc tgcttttaca
     5521 gtttagaata aaaaagctgt ggctaaaggt cacagctttt tgctactttt taaaggcagg
     5581 agaatattaa aaaggagcaa attatgagca atataaaaat aatagcaagt aataaatgtt
     5641 ggattgaaga tatagcaagg aaacaacttg aagatatttc aaagttaaat ggaattttaa
     5701 gagtagtagg attacctgac ttacatgcag gtaaaatacc tgtaggttta gcagttgaga
     5761 ctaaaaatat tatttatcca catataattg gaaatgatat aggatgcgga atgactttat
     5821 ttaaaactgg ggttctaaaa aagaaattta aaaaagacaa atggattaag tcacttagta
     5881 agattaaaga tttgtccgat atagaaataa aaaacacata taaagaagaa tgtccaattt
     5941 taaatttagg aactataggg agtggaaatc attttgtaga aattcaatgt ataagtgaaa
     6001 tttataataa agaacaattt gaacaattaa aattttcatc tgatgatatt atgatgttag
     6061 ttcactgtgg gtcaagaaat tatggagaag atattttaaa aaaattttat gataaagatg
     6121 gacttgaagt tgaaagtgag aaagctatag attatattaa aaaacacgat aatgctttaa
     6181 tgtgggcaga gcgtaatcgt gaagctatca gtaaaaaaat tatgcagtca ataggtacat
     6241 ctggatatgt tgaaacaata ttctctataa atcataattt tatagagaaa agggaagata
     6301 aatttataca tagaaaaggt gctgtttcaa gtgaaagagg agctgtgatt ataccaggtt
     6361 caagaggcag tctatcatat atagttatgc ctactgaaaa tacagagata tctttatatt
     6421 ctctatcaca tggagcaggt agaaaatggt ctcgttcagt ttgtaaatct cgccttaaaa
     6481 gtaagtatag taaagatact ataaaacaaa ctaaatttaa aagtcagatt atatgtaatg
     6541 atgtaaattt attatttcaa gaagctccag aggcatataa gaatatagag cagattattg
     6601 aaagtttgat agaatatgaa cttattcaag tagtggcaac tatgaagcca ttgattactt
     6661 ataaaggata atttttaaag ttaaaaaaga ttaaaattat attataaata gctaatttta
     6721 tagaacattt aaaagtgttt tattattagc tattttttta ttttgtagag acgataattt
     6781 atagagctaa attctttgat atataatgat tacaaagtta gactgtattg gaaaatgcac
     6841 atacatgaat tgatgacaat ataagtgatt cccaaatata aatgaaagta taagcttatt
     6901 ttcactataa aaattttcac tgtacaaaaa cattaatgac attattttta ttgacataaa
     6961 tatataattt atggaataat attagaagca ctgatataag tgtttaaata agaatagaaa
     7021 aggagaagtg ttttatgaaa aaaaatacta acattaatga gtccggagtt aaacttctta
     7081 ataaataagg agtttgatat ataataactc cttatttatt aagttgttcg caaaataact
     7141 attatcaaag taaatgatag ggtgatttaa aagacgataa cttataaata aaggagaaaa
     7201 aataatgaat agtaatacat ttgaaagatt acaactaaat gaagttaaag aattaataaa
     7261 aatacattgt gtaagttcac taggaaaaaa tttaatagat aaattaactc ctagtgggaa
     7321 tattggagta gtaagaagga aattagcaga aaataaagaa gctagaaaga taattgaaaa
     7381 tagtaatcac ataccacttg aaggattgtt taatgcaggt tctacaatag ataaaattga
     7441 aaaaggaatg ataatagaac ctgttgaact tgtaaatatt gaagattttt taagaggttg
     7501 taggaagatg aaagctttta tgttagaaaa agaattttat tcacctacat taagttctta
     7561 tgccttaaat ataacagaat gtaaaagtat agaagatgag ataaattact gtataaaatc
     7621 taataaagtt gattctaatg ctagtaaaga attaaaaaag ataagacgaa atatagaaat
     7681 tacagaagga aagataaaag atagattaaa taaatttata acatcaactg taaataaaaa
     7741 gtatatacaa gagtttataa taagtaaaag aaatgataga tatgtaatac caattaaatc
     7801 ttcttataaa aatgaagtta atggtactat attagataca tcatcaaaag gaaatactgt
     7861 atttattgaa cctattagtg tttcaaattt aagtacagag ttaactatgc taaaagctga
     7921 tgaaactatt gaagaataca aaatattatc ttatttaaca gaacttatat ttgagaagat
     7981 aagtcagata aaattaaata tagagatact ttcagaatac gatatggtat ttgcaaaagc
     8041 taagtatagt caaaaaataa aaggaattac tccaaaaata aataataatg gctatataaa
     8101 aataattaaa ggtaaacatc cacttctaac aggagatgca gtacctttag attttgaaat
     8161 aggcaaaaat tatagaagtc ttataataac aggtcctaat gcaggaggaa aaactgtaac
     8221 ccttaagact gttggtttac taactttaat ggttcaatgt ggatttgata tttctgcaaa
     8281 agaaggtagt gaatttagtg tatttgaaaa agtttttgta gatatagggg ataatcaaag
     8341 tattgaaaat gccttaagta ctttttcatc acatataaaa aatattgcag agattatgag
     8401 tttatcaaat aattctactc ttgttctgtt tgatgaaata ggaagtggaa ctgaacctaa
     8461 tgaaggagct ggtttagcaa tatcattatt agaagagttt tacaaaatgg gatgtataac
     8521 tatagcatca actcattatg gagagataaa aaagtttgct acattgcatc cagaatttga
     8581 aaatgctggt atgatgtttg ataaagaaac gttagaacca ttgtataagt taactattgg
     8641 aaaatctgaa gatagtaatg ctctttttat ttctaaaaaa atgggaataa aaaatagagt
     8701 tttagataga gctaaagaat atgtaattga tagaaactac aatttagatt tagttaaaag
     8761 aagtaagcta caatctaata ttgaagataa aaatagttct gaagtcattt taaactatac
     8821 agattataat gtaggggata aggtaaaatt actagatgaa gatgattttg gaattgtata
     8881 taagcctatg gacaagttta ataatgtaga agtattgttt aatgataatt ttatttcagt
     8941 aaatataaaa agattacaac ttagcataaa agcatcagaa ttgtatccag aagggtatga
     9001 tttagatgta ttatttacta gttttaaaga aagaaaatta gaaaaagata ttcaaagagg
     9061 ttcaaaaaaa gctcttaaaa agattcagaa agaaattaga gagaatagaa aataaatata
     9121 aaaagcacaa aagaaagcaa tctaaagaga aaagtttatc tttagattgc tttcttatta
     9181 acatatcttc ataaatccaa tgactaacaa gattaaacca cttaaccaag ataagtttaa
     9241 atttacgttt ttaacaaaca tatttcctag taaacaacca agtaatactg caattatatt
     9301 tgatattaaa gaaaatagaa taacttgtat ataattcaca cctacaaggc cactaccaaa
     9361 accgatagct aatccatcta agcttaaagc aagtgcaagt gtaaatgctt cagcagattt
     9421 aagcacttta gatttacttg tatctaagac atcaggttcg atacttacat taaaatttaa
     9481 tttaaggtct aacatattaa aattataatt ctttgagtgt atagattttt tcttaaaata
     9541 agatttaaaa aaactttcaa ttagtctagc acttcctaat aaaaataaaa taaagaaaca
     9601 tattaacatt gttatatttt gaggtaaaaa gtctctaact attgtacctg caaaaagcga
     9661 tattgctaaa atagctgaac aaactacgct tataattata tttgaatata agggaacttt
     9721 aactttattt acgccatatc caaagcttgt cacaaaggca tctatacaaa gagaagtaac
     9781 taataaaatt gattcaatca cagtagatta acatcctttc tcttaaattt tgtacttata
     9841 ttagttatag tattgtaaaa atggataaat tgttacagat aatccaataa attgttgata
     9901 aaatttcaac attatacaac acctaaataa caaaagaatc atatcatata ataatataaa
     9961 accaatcata ataaagcagg tgaaaataat ggaacaacat agtaaggttg ggaatttcgg
    10021 tgatttgttg aaagttttat tagatgaaaa agaattatca atgggagaac taagtaaaaa
    10081 aagtggaatt gataaatcta ctatatctcg tatagctaat aataaacaaa agccaaatat
    10141 aaatcattta gaaaagatgg caatacattt aaatattaac ctagaagaac tgttgaaagc
    10201 ttcaggatat gaatttagaa acagcaataa tcaaatattt aatgcagata gtgattttag
    10261 taactttgat gatattcttg gatttgcaaa tttaatcaat gataagaact ttaatggaaa
    10321 tattgaaaaa gagttaagta agtgtaagtt atatgtccaa acagatgaag gtaaaaaatt
    10381 actttttgat aattttaata aaaaaataga ttctattgaa aaacaaggtc aatttacaga
    10441 tagattaaga caaatgtatg ctgatttttg tacagatgga cttacaataa agaaatattt
    10501 attgattgga agtatgctac tttactttgt tatatcaaca gatgtgattc cagacttcgt
    10561 gttcccaata ggatttatgg atgatttagt agcattaaat atagttacaa aattacttaa
    10621 aaatgataag taagttttag
//
LOCUS       DAEORM030000093        10604 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.099, whole genome shotgun sequence.
ACCESSION   DAEORM030000093 DAEORM030000000
VERSION     DAEORM030000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10604)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10604)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 10604)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10604
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.099"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            274..1314
                     /locus_tag="KRH23_003545"
     CDS             274..1314
                     /locus_tag="KRH23_003545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54 interaction domain-containing protein"
                     /protein_id="HHS5226815.1"
                     /translation="MDKHSDSVMYGGMEVYNIWGTTTVDSIIGESDVMRALKNRICKI
                     GNSDSTVAITGESGTGKELIARAIHLAGNRGNKTFVAINCAAIPEPLLESELFGYTKG
                     AFSGADSKGKIGKFELANGGVVFLDEIGDMPIQLQSKLLRVLQEKKFTRIGSNELIDI
                     DVRIISATNRDLFELVKENKFREDLYYRLNVIPLEVPPLRERGDDIQILINNFIDKYS
                     RKMKKNVYHIEPDVEQMLLKYPWPGNIRELENTIELALNLLEEDGIIHKGIINRKILE
                     YFKLNNINIKLLEESDYEISMEQDILTLEEFERAYIKKVLKFYGNDTKSKKLAAKKLG
                     ISLATLYRKIDV"
     gene            1670..2992
                     /locus_tag="KRH23_003546"
     CDS             1670..2992
                     /locus_tag="KRH23_003546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015851 - nucleobase transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-xanthine permease family protein"
                     /protein_id="HHS5226816.1"
                     /translation="MFDIDGRPPILKCLPLSMQHILAMIVGTVTVPIVVGGAVGVSPT
                     QITLLVQYALIIAGISTLIQLYPIGNIGSRLPIIFGVGFTYVPTLVAVGGNYGLASIL
                     GAQLIGGVATVLIGIFIKKIRKFFPNIVAGTVVFTIGLSLYPIAINYMAGGVNSPTYA
                     SMQNWAVAAITLVVVIGLSQFAKGYAKLAAIFLGIIVGYCVSLVLGIINFDPIREATW
                     FAIPKPLEFGMEFDMPVIISVVIVSIINAVQAIGDLSATTMGGMDRNITDKELSSGVI
                     GSGICTMIGALFGGLPPSSYSQNVGMVAMNKVISRFVLGIAGIFMLLSGFVPKFGALM
                     TTIPYSVLGGATISIFSMITMTGIKLIITEELSSRNITIVGLAIALGMGITSVPAAQE
                     AFPSFVKLVFGESPIVIATLVAFVLNLIIPNKSLEDEAKERAVMEETN"
     gene            3289..4650
                     /locus_tag="KRH23_003547"
     CDS             3289..4650
                     /locus_tag="KRH23_003547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015851 - nucleobase transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-xanthine permease family protein"
                     /protein_id="HHS5226817.1"
                     /translation="MKTRNTSKYDVDGIPPLKESIPLALQHLLAMIVGNMVPAILIAN
                     VVGLNQGQATMLIQGSMLAAGLATFLQLYPIPLFKGFKLGSRLPVMMGMSYVFLGACL
                     SVAAKDGLAALFGAQIAAGVIVFFVGFGVKKIRHIFTPIVSGTIIACMGLGLFATAIK
                     NLAGGEGTQTFGSPINFTVGVIVAFVIIMINKYGKGLVKNSSILIGILVGYAISLVLG
                     LVDFSAVQGAAIVSLPTPAAFGLEFRPELIVMFTIIYIIGIADMMGACTIATVGAMDR
                     EVTDEELASVVLGNSITSIISSLFAALPTGVFSQNTVIVSMNKVTSRFVIALGALVLL
                     LAGISPALGAIMTTIPSCVVGGATLVVFSSIAMSGFSIMSMDGFTEENNLIAGVSIAT
                     SMGLTTAPQVLDQFPETIGTVLGGSSIVSGAIIAILLQTLFKLKSRKSAENVTSNLEE
                     NIG"
     gene            4723..6117
                     /locus_tag="KRH23_003548"
     CDS             4723..6117
                     /locus_tag="KRH23_003548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HHS5226818.1"
                     /translation="MIDILIKNAIIVTVNKDRDVIFDGAIAIKGDRILDIGNTVDIEP
                     KYLDAKKVIDANGKVIFPGFINTHNHLFQVLLKGLGDDMALHEWLNTMMFPSAKFLTE
                     QDTYDAAMLGCMEGLKSGITTMVDYMHTHNRPGLTDGIVKAYKDLGIRGVVGRGCIDL
                     GIHKELIEDVETVEKDLRRVFEKYHNSENGRIKICVAPSSMWAISEEMGKMLWNIVKE
                     YDSYFTVHISETEFARTATKDIHGEIDIKLLEKWGIVGPEVVAVHCVCITDEDMEMLK
                     KYDIKVSHNVASNMYLASGVAPVPEMLKKGINVSLGLDGAASNNAQDMVELMKLTALQ
                     HKVNNCDPLAISAEKVLEMATIEGARTLRMEDEIGSLEIGKKADLVIFNSMLSPKSIP
                     LHNPVSTLVYSASMHNVESVLVDGNVILENGKVTTIESEEQVLLNAQHAAEELCKRAN
                     VTNRMEGHKWNSLY"
     gene            6179..6649
                     /locus_tag="KRH23_003549"
     CDS             6179..6649
                     /locus_tag="KRH23_003549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="(2Fe-2S)-binding protein"
                     /protein_id="HHS5226819.1"
                     /translation="MEKIKLNINDYMYEIEVEKNETLLHVLREKLNLTGAKQGCNSGS
                     CGACKVLIDGVDMKSCKLLAKNCEGKVIYTIESFANGENLHPIQEAFIEVGAVQCGYC
                     TPGMIITTQALLNRNASPNEDEIREAFKENLCRCTGYVKIIEAVKLSAARLGGR"
     gene            6652..8868
                     /locus_tag="KRH23_003550"
     CDS             6652..8868
                     /locus_tag="KRH23_003550"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043546 - molybdopterin cofactor binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine dehydrogenase family protein
                     molybdopterin-binding subunit"
                     /protein_id="HHS5226820.1"
                     /translation="MEKVIGKSYPLKDAALKVTGQMKYVADMKPQNVLYAKMLLSPVA
                     HAKIKSIDTSEAEKVVGVRAIATYLNTSQRKYNGSLRFYEHNIPENEVIFSDTVRFVG
                     DRVAAVAAETPEIAEKAVKLIKVEYEELPAVFTIQDAIKEDAICIHGDSNIVSQNNIN
                     GGDVEKGFKECDYIFEDEYSTPAIHHSAIETHSVIAHYDYNDKLTVHTPCQNTFGFRI
                     ILSQIFGMSLNKVRVIRPAIGGSFGGKLELTIEPVAAALSKMTRRPVKMVLTRKESMI
                     STRTRHGSFVKLKTGVNKDGEVIAQDIKIYTNTGAYASSALNVIGALSHKVFKVYKIP
                     NIKFTGMPVYTNTPIAGAMRGYGSPQIFMAQQAQFAKIAKEIGMDLVDFQNKNAVEPD
                     DVDIIFRGSLGNPRVLDCIEQGKKMFKWDEKKKLPKEEGKYLRGIGMAIGAHGNGVFG
                     AHRDVVTLTLKLNEDGTLTLLTGAHDMGNGVVTMQTMMVAEVLGITPDKVDTFETDTD
                     ACTFNLGDYASRGVFVEGGGAKKTAEKLKNLILEEAEKLLETSKEDLYLDNGCVISKL
                     DENVKASLSDVAVYSQSKSLRELTVVEDYSSPAGRTSYGVHFAEVLVDKETKDIKVVD
                     FVAVHDVGRVINPLNLEGQLEGGIHMGLGYALSEELAFDEQGRPKATDFKTYKLFRTV
                     DMPKCQVAFVDGYEKAGPFGGKSIGECAVVPVAPAVANAVYNATDVEIHSLPIKLK"
     gene            8948..9619
                     /locus_tag="KRH23_003551"
     CDS             8948..9619
                     /locus_tag="KRH23_003551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HHS5226821.1"
                     /translation="MAKILGICGSPRKGATEYAVLEALKEAETIPGIETEYWSVRGKK
                     ISPCVHCDACIRKETMCIIKDDIQELEQKILEADGIIVGSPVYDMNITAQLTAVFNRL
                     RPMYLVHPGKLQNKVGAAITTGGTRYGGQELTKLPIINFFLMHEMLVSGGLGGCYIGG
                     TIWSKDGKAKGAQEDETGMDTVKRLGKGAAEAVMVSKFGLEKWNVVKEELDVKKDEKS
                     PLRDH"
     gene            9982..>10604
                     /locus_tag="KRH23_003552"
     CDS             9982..>10604
                     /locus_tag="KRH23_003552"
                     /EC_number="4.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008838 - diaminopropionate ammonia-lyase
                     activity [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopropionate ammonia-lyase"
                     /protein_id="HHS5226822.1"
                     /translation="MLKEIKWKVNNLPKGDKENCIKFLNEEEITKVRNFHKSFPQYKE
                     TPLANLEGLAKKLGVAGVYVKDESYRFGLNAFKVLGGSYSMGRYLAQRLDTDISELGY
                     DKLTSKEIKEKLGEITFFTATDGNHGRGVAWTANKLGQKSVVLMPKGSSEFRLNKIKG
                     EGADASITDLNYDDAVRLANDYAEADDHGVMVQDTAWDGYEEIPAWI"
BASE COUNT         4012 a         1210 c         2116 g         3266 t
ORIGIN      
        1 gagtagtata aaaaatttaa taagaactta aattaaaaat tttaaaaatt atttccatat
       61 aaaatatggc attgtaattg cttatttaat agaggatttt tgtaaaatga agaaagtata
      121 tctatcaaat taaaactaag tagatatact ttttattaag ttttgtttta aaataatatt
      181 attaaattat aactaagctt ttctgttatg atataattaa atagataatg tgaatgatta
      241 ttatatagaa tacttatttg gagttgatat tttatggaca aacacagtga ttcagtaatg
      301 tatggtggaa tggaagtata taatatttgg ggaacaacaa cagtagactc cataattgga
      361 gagtctgatg taatgcgtgc tcttaagaat agaatttgta aaattggaaa tagtgattct
      421 actgtagcta taactggaga aagtggcact ggaaaagaat taatagcaag agccattcat
      481 ctcgcaggaa acagagggaa taaaacattc gttgctataa actgtgctgc tataccagaa
      541 cctttactag aaagtgaact ttttggatat acaaaaggag cttttagtgg agcagattca
      601 aaaggtaaaa ttggtaagtt tgaattggcc aatggagggg ttgtattttt agatgagata
      661 ggagatatgc caattcaact acaatcaaag ttattgaggg tattacagga aaagaagttt
      721 acgagaatag gttcaaatga actaattgat atagatgtta gaatcatatc agctactaat
      781 agagatttat ttgagttggt taaggaaaat aaatttagag aagacttata ctatagattg
      841 aatgtaatac ctttagaagt gcctccactt agagaaagag gagacgatat acaaatatta
      901 ataaacaatt ttatagacaa atattcgaga aagatgaaga aaaacgtgta ccatatagag
      961 ccagatgtgg aacaaatgtt gcttaagtat ccttggccag gaaatattag agagttggaa
     1021 aatactatag aactggcatt aaaccttctt gaggaagatg gaataataca taaaggaata
     1081 ataaatagaa agatacttga atattttaag ttaaataata taaatataaa gttacttgag
     1141 gaaagtgact atgagataag tatggaacaa gacatactta cacttgaaga gtttgaaaga
     1201 gcctatataa agaaagtgtt aaagttttac ggaaatgata ctaagtctaa aaaactggct
     1261 gccaaaaaac ttggaatatc actagctaca ttgtacagaa aaatagatgt ataataatta
     1321 ggctttttat tctcaattct aaaatttgaa attataaaat tgataaaaaa cacttggaaa
     1381 actattttct aagtgttttt ttgtgtaata gcattttatt atccaaaaat aaaaaaaatt
     1441 taaaagaatt taaaaaaata aatgctttaa taaattatca aatactaaca aatataataa
     1501 aaattatata tgtaaaacaa ttatgttaaa aaattggcat tataattgct tcatattaag
     1561 ttgagatgac aaaataaaaa aagaaaggat gttgtgtgag ataataataa ctgtcattaa
     1621 aaaatagttg ggagtgataa ccttgagtaa atatcaaaag aatgtttcta tgtttgatat
     1681 tgatggaagg ccaccaattt taaagtgttt gccactatca atgcaacata tactagcaat
     1741 gatagttgga actgttacag tacctatagt cgtaggagga gctgtgggtg ttagccctac
     1801 acaaataaca cttttagtgc aatatgcatt aataatagct ggtatatcaa cacttataca
     1861 actatatcca ataggaaata ttggttcaag attgcctata atttttggag ttggttttac
     1921 ttatgtacca acacttgtag cagtcggagg aaattatgga ttagcaagca ttttgggtgc
     1981 acaattaata gggggagtgg ctacagtatt aatagggata ttcataaaaa agataagaaa
     2041 attttttccg aatatagttg caggaacagt ggtttttaca attggattat ctttgtatcc
     2101 tatagcaata aattatatgg caggtggtgt aaatagtcct acttatgcct ctatgcaaaa
     2161 ctgggcagta gcggctataa cattagtggt agttataggt cttagtcaat ttgcaaaagg
     2221 atatgcaaaa ttggcagcaa tatttttggg aattatagtt ggatattgtg tatctttagt
     2281 tctgggtata ataaattttg accctattag agaggcaact tggtttgcga tacctaaacc
     2341 gcttgaattt gggatggaat ttgatatgcc tgtaataatc tcagtagtaa ttgtaagtat
     2401 aatcaatgct gttcaagcaa ttggagattt atcagctact acaatgggag gcatggatag
     2461 gaatatcaca gataaggaat tatcaagtgg agtaatagga agtggaattt gtactatgat
     2521 aggagctttg tttggaggtt taccaccatc atcatatagc caaaacgtgg ggatggtagc
     2581 tatgaacaaa gtaataagta gatttgtgct tggaatagct ggtatattta tgttattgtc
     2641 ggggtttgtg cctaaatttg gtgcattaat gactactata ccatattctg ttttaggagg
     2701 agctacaata tctatattta gtatgataac aatgacaggt ataaagttaa ttattacaga
     2761 agagttgtca tcaagaaata ttaccattgt tggtttggca attgccttag gcatgggaat
     2821 aacatcagta ccagcagccc aagaggcatt tccttcattt gtaaagttag tatttggaga
     2881 atctccaata gtaattgcaa cattggttgc attcgtttta aatctaataa taccaaataa
     2941 aagtctagag gatgaggcta aagaaagagc tgttatggaa gagactaatt aagatataat
     3001 aatttaaaag aattgtttaa attatttagt atgagattgt tagattattt ttgatagcta
     3061 ttcattttaa taaaaaattt aacaaataaa tatataccag gcaattaatg ttcatttaag
     3121 ttgaaaatcg gggagggaat atttagaaat ttgttaattt tttataaaaa tagctcagtt
     3181 tagctgtgtt tatcggttga gcaataaatt catggtcata aaaatattta tagaaaataa
     3241 ttataaaaat atttagtcaa gatatttatg tatgggagga tttattttat gaaaacacgt
     3301 aatacttcaa aatatgatgt cgatgggata ccaccactaa aggaatcaat acctttggcc
     3361 ttacaacatc tgttagcaat gatagtagga aatatggtac ctgcgatatt aatagcaaac
     3421 gtggtaggac ttaaccaggg gcaagcaaca atgttgattc agggttctat gttagcagca
     3481 ggtttagcaa cgtttttaca gttatatcca atacctttat ttaaaggatt taagttaggt
     3541 tcaagattac ctgtaatgat gggaatgagt tatgtatttt taggagcttg tctttcagta
     3601 gcagctaaag atggtttagc agctctattt ggagcacaga ttgctgctgg ggtaatcgta
     3661 ttctttgtag gatttggagt taagaaaatt agacatatat tcactccaat agtttctgga
     3721 actataatag catgtatggg acttggacta ttcgcaacag ctataaagaa tttagctgga
     3781 ggagaaggca cacaaacatt tggaagccca ataaacttca cagtaggagt tatagttgct
     3841 tttgtaataa taatgataaa taaatacggt aaaggtttag taaaaaattc ttcaatatta
     3901 ataggaatat tagtaggtta tgctatatct ttagttttag gattggttga tttctcagcc
     3961 gttcaaggag cagctatagt atctttacca acaccagcag cttttggatt agaatttaga
     4021 ccagagttaa tagtaatgtt tactattatt tacataatag gtatagctga tatgatgggt
     4081 gcctgtacaa tagctacagt aggagcaatg gatagagagg taactgacga agaattagca
     4141 tcagttgttt taggaaattc tataacttct ataatttcat cactatttgc agctcttcca
     4201 actggagtat ttagccaaaa tacagtaatt gtatctatga acaaagttac aagtagattt
     4261 gtaatagcac taggggcact tgtattatta ctagcaggga tatctccagc attgggtgca
     4321 ataatgacaa ctataccatc ttgtgttgtt ggtggagcaa ctttagtagt tttctcatca
     4381 atagcaatgt ctggtttctc tattatgagt atggatggat tcactgaaga aaacaatctt
     4441 atagcaggtg tatctatagc aacaagtatg ggtcttacaa ctgctccaca agttttagac
     4501 caattcccag aaacaattgg aactgtcctt ggagggtcaa gtatagtttc tggagcaata
     4561 atagctatat tacttcaaac attatttaaa ttaaagtcac gtaaaagtgc tgaaaacgtt
     4621 acttcaaatc ttgaggaaaa tattggataa atgtattaga tataatatga gaaaaccata
     4681 tggtaaaatg ttgtaatgaa agtattcaaa gggggattta agatgattga tatactaata
     4741 aaaaatgcaa taattgttac agttaataaa gacagagatg ttatatttga tggagcaata
     4801 gctattaaag gtgacagaat cttggacata ggaaatacag ttgatattga gcctaagtat
     4861 cttgatgcta aaaaagttat agatgctaat ggaaaagtaa tattccctgg ctttataaat
     4921 actcataatc acctgttcca agtgttatta aaaggtttag gtgatgatat ggcacttcat
     4981 gagtggttaa atacaatgat gtttccatca gcaaaattct taacggaaca agatacttat
     5041 gatgctgcaa tgcttggatg tatggaaggt ttaaaaagtg gtataactac aatggttgat
     5101 tatatgcata ctcacaatag accaggactt acagatggaa tagtaaaggc atataaagat
     5161 ttaggtataa gaggggttgt aggtagaggt tgtatagatt taggtattca caaagagctt
     5221 atagaagatg tggaaacggt tgaaaaagat ttgagaaggg tattcgaaaa atatcataat
     5281 tcagaaaatg gaagaataaa aatctgtgta gctccttctt caatgtgggc tatatctgaa
     5341 gaaatgggta agatgctttg gaatatagtt aaagaatatg attcatattt tacagttcat
     5401 atatctgaaa cagaatttgc aagaacagca acaaaggata tacatggaga aatagatata
     5461 aaattacttg aaaaatgggg tatagtaggt ccagaagttg tagcagtaca ttgtgtatgt
     5521 ataactgatg aagacatgga aatgcttaaa aagtatgaca taaaagtttc tcataatgta
     5581 gcaagtaata tgtatcttgc ttctggtgtt gcacctgtgc cagaaatgtt aaaaaaaggt
     5641 ataaatgtga gtttaggtct tgacggtgca gcaagtaata acgcacaaga tatggtagaa
     5701 cttatgaaac taacagcttt acaacacaaa gtaaataatt gtgaccctct ggcaatttct
     5761 gcagagaaag ttcttgaaat ggctacaatt gagggagcaa gaactcttag aatggaagat
     5821 gaaataggtt ctttggagat tgggaaaaaa gctgacctag taatatttaa ctcaatgctt
     5881 tctccaaaat caatacctct tcacaatcct gtatcaactt tggtatactc agctagtatg
     5941 cacaatgtag agagtgtttt agttgatgga aatgtaatac ttgaaaatgg aaaagtaact
     6001 acaattgaaa gtgaagaaca agtgttgctt aatgcacaac atgcagcaga agaattatgt
     6061 aagagagcta atgtaactaa tagaatggaa ggacataagt ggaatagctt atactaatat
     6121 taaaataaga ttgtaataat attctattac aacattagtt tatctgtagg aggagaaaat
     6181 ggaaaaaata aaattaaata ttaatgatta catgtatgaa atagaagttg aaaagaatga
     6241 aactcttttg catgtacttc gtgaaaaatt aaatctaact ggagcgaaac aaggttgtaa
     6301 tagtggcagt tgtggagcat gtaaagtttt gatagatgga gttgacatga aatcttgtaa
     6361 acttcttgca aaaaactgcg aaggtaaagt tatatacact atagaaagtt ttgctaatgg
     6421 agaaaatctt catccaatac aagaagcttt tatagaagtt ggagctgtac aatgtggata
     6481 ttgtactcct ggtatgatta taacaacaca agctctttta aatagaaatg catctcctaa
     6541 tgaagatgaa attagagaag cttttaaaga aaatctctgt agatgcacag gatatgtaaa
     6601 gattatagaa gctgtaaaat tatctgcagc tagattaggg ggtagataat tatggaaaag
     6661 gtaataggaa aatcataccc tctaaaagat gcagctttaa aagttactgg tcaaatgaaa
     6721 tacgtggctg atatgaaacc acaaaatgta ctttacgcta agatgctttt aagtcctgta
     6781 gcacatgcaa aaataaaaag tatagataca agtgaagctg agaaagtagt aggtgttaga
     6841 gctatagcta cttatctcaa tacatcacaa agaaaataca atggttcatt aagattttat
     6901 gagcacaata tacctgaaaa tgaagttata ttttcagata cagttagatt tgttggtgac
     6961 cgtgttgcag cagtagctgc agagactcca gaaatagcag agaaagctgt aaaacttata
     7021 aaagttgaat atgaagaatt gccagctgta tttactatac aagatgcaat aaaagaagat
     7081 gctatctgca tacatggaga ttcaaatata gtttctcaaa acaacataaa tgggggagat
     7141 gtagaaaaag gcttcaagga atgtgactat atatttgaag atgaatactc tactccagca
     7201 atacatcata gtgcaataga gactcatagt gtaattgcac actatgatta taatgataaa
     7261 ttaactgtac atacaccttg ccaaaataca tttggattta gaataatact atctcaaatt
     7321 tttgggatgt cattaaataa agtaagagtt ataagacctg ctattggagg ctcatttggt
     7381 ggaaaattag aacttacaat tgaaccagta gcagccgcat tatcaaaaat gacaagaaga
     7441 ccagttaaaa tggttcttac aagaaaggaa tctatgatat cgacaagaac tcgtcatggg
     7501 tcttttgtaa aattaaaaac tggtgtaaat aaagatggtg aagtaatagc acaagatata
     7561 aaaatatata caaatacagg agcatatgca tcaagtgctt taaatgttat aggagcactt
     7621 agtcataaag tatttaaagt ttataaaata ccaaatataa agtttactgg gatgcctgta
     7681 tatacaaata caccaatagc aggagctatg agaggctatg ggtcacctca aatatttatg
     7741 gctcaacagg ctcaatttgc gaaaatagca aaggaaatag gtatggattt agtcgatttt
     7801 caaaataaaa atgcagtaga gccagatgat gtcgatataa tcttccgcgg ttctcttgga
     7861 aatcctagag tattggattg tatagagcaa ggtaagaaga tgtttaagtg ggatgaaaag
     7921 aaaaaacttc caaaagaaga aggaaaatat ttaagaggta taggtatggc aataggtgca
     7981 catggtaatg gagtttttgg tgcacataga gatgttgtta cattgactct taaattaaat
     8041 gaagatggta cgttgacact actaacagga gctcatgata tgggtaatgg tgttgtaact
     8101 atgcaaacaa tgatggtagc tgaagtttta ggaataacac ctgataaagt tgatacattt
     8161 gaaactgata cggatgcatg tacattcaac cttggtgact atgcaagtag aggggtattt
     8221 gtagaaggtg gaggagctaa aaagacagca gagaaattga aaaatcttat attagaagaa
     8281 gcagaaaaat tacttgaaac atcaaaagaa gatttatatc tagacaatgg atgtgtaatt
     8341 agtaaacttg atgaaaatgt aaaagcatca ctttctgatg tcgcagtata tagtcaaagt
     8401 aaatcattaa gagagttaac tgttgttgaa gattattctt caccagctgg acgtacttct
     8461 tatggtgtac attttgctga agttttagta gataaagaaa ctaaggatat aaaagtagtt
     8521 gattttgtag ctgtacatga tgttggtaga gttataaatc ctctaaattt agaaggacaa
     8581 ttagaaggtg ggattcatat gggtctagga tacgcattga gtgaagaatt ggcatttgat
     8641 gaacaaggta gacctaaagc tactgatttt aaaacatata aattatttag aactgtagat
     8701 atgccaaaat gtcaagttgc atttgtagat ggttatgaaa aagctgggcc ttttggtggt
     8761 aagagtattg gagaatgtgc cgttgtacca gttgcgccag ctgttgcaaa tgcagtatat
     8821 aatgcaactg atgtagagat acattcatta ccaataaaat taaaatagta gaaaaagcag
     8881 aaataacaat ttattgtatt tgtaaatgga taataaaaat agatttattt ggtgaggaga
     8941 tattattatg gcaaagatat taggtatttg tggaagtcca cgtaaaggag caacagaata
     9001 tgcagtgtta gaagctttga aagaagcaga aactatacct ggtatagaaa ctgagtattg
     9061 gtcagttaga gggaaaaaaa taagtccttg tgtacattgt gatgcatgta taagaaaaga
     9121 aactatgtgt attataaaag atgatatcca agaattagag caaaaaatat tggaggcaga
     9181 tggaattata gtaggttctc cagtttatga tatgaatata actgctcaac ttacagcagt
     9241 atttaataga cttcgtccaa tgtatttagt tcatccagga aaacttcaaa ataaggttgg
     9301 tgcagctata actactggtg gaactagata tggtggccaa gaattgacaa aacttcctat
     9361 aataaatttc ttcctaatgc atgaaatgtt agtgtctgga ggtttaggtg gatgctatat
     9421 aggtggtaca atatggagta aagatggaaa agcaaaaggt gcccaagagg atgagacagg
     9481 tatggacaca gtaaaaagac ttggaaaagg tgcagcagag gcagttatgg tttctaagtt
     9541 tggtcttgaa aaatggaatg tcgtaaaaga agaattagat gttaaaaaag atgaaaaatc
     9601 acctcttaga gaccactaaa gatttattat attattgaat atatacaaat agtgatgtaa
     9661 tagattattg catcactatt ttatgtttta atttagattt tataaatttt atattaaaaa
     9721 atatagaaac aaagtgtttt gagatttatt tttaaatttt aaaaatgaga attaaaaagt
     9781 gagaagatag aaaaggtttt ttagttatta aattctacat acattgtatg aactaaagat
     9841 agaaaagaaa aaataataaa agcattgcaa tttctatact aaagagtcat ggaaaaatat
     9901 ctagtatata tttagtattg gcatgttaat tgcttatata ttaaagtata aaaatttaac
     9961 aataatttgg aggtatttta gatgttaaaa gaaattaaat ggaaagtaaa taatttgcca
    10021 aagggcgata aggaaaattg tatcaaattt ttaaatgaag aagaaataac taaggttaga
    10081 aattttcaca aaagctttcc tcaatataaa gaaactccat tagcaaacct agaaggttta
    10141 gcaaaaaaat taggtgttgc aggagtatat gtaaaagatg aatcttatag atttggttta
    10201 aatgcattta aagtattagg tggttcttat tctatgggta gatacttagc tcaaagatta
    10261 gatacagata tatctgagtt agggtatgac aaattgactt cgaaagaaat aaaagaaaaa
    10321 ttaggagaaa taactttctt tacagctaca gatggaaatc acggtagagg agttgcttgg
    10381 acagctaata aattaggtca aaaatctgtt gtattaatgc caaaaggttc ttctgaattt
    10441 agattaaata aaattaaagg agaaggtgca gatgctagta taacagactt aaattatgat
    10501 gatgcagtaa gattagctaa tgattatgca gaagctgatg accatggagt aatggttcaa
    10561 gatacagcat gggacggata tgaagaaata ccagcatgga taat
//
LOCUS       DAEORM030000094        10364 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.100, whole genome shotgun sequence.
ACCESSION   DAEORM030000094 DAEORM030000000
VERSION     DAEORM030000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10364)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10364)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 10364)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10364
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.100"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            complement(358..1629)
                     /locus_tag="KRH23_003553"
     CDS             complement(358..1629)
                     /locus_tag="KRH23_003553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HHS5226823.1"
                     /translation="MLKVLKGNIIFTKTSETFTVFENSYIILEKGKVKGIFKEIPKEY
                     KNLKVVDYTDKLIIPGMNDLHAHASQFKNLGMAMDKELLPWLETYTFPEESNYKDIEY
                     ATKMYKKFVKELWKSGTTRIAVFATVHKESSMKLMDIFKEVGLGAYVGKVNMNMNCPD
                     TLLENTLDSIADTEEIINKYSDTDSIVKPIITPRFIPSCTSELLKGLGDLCLKYNIPI
                     QSHLSENYDEIEWVRSLEPESKFYGDAYNRYNLFGQTPTLMAHCVHCSQDEIDLMREN
                     NVMAVHCPASNFNVGSGAMPIRKLIDNNIRLALGSDISGGHTLSIFKAMVSAIQLSKL
                     YWVNSGKKYNFLSLSEAFYIATKSGGSFFGKVGSFEEDYDFDALIIDDSNLNHDNYSI
                     LERLERFIYVGDDRNIIHRYVCGKLIEEPNI"
     repeat_region   2276..4015
                     /inference="COORDINATES: alignment:CRISPRCasFinder:4.3.2"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=2276..2304
                     /rpt_unit_seq="gttttatattaactaagtggtatgtaaat"
     gene            4424..4711
                     /locus_tag="KRH23_003554"
     CDS             4424..4711
                     /locus_tag="KRH23_003554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226824.1"
                     /translation="MKKFLYALYSFIVIIANFRLKEKNYNFILLAIFFILLLIQNGVL
                     KTGYQNRATFYQDNYFNGEDKNDKIKFMTIKIFIFLSLPLCFNILFNYLTS"
     gene            complement(5250..5801)
                     /locus_tag="KRH23_003555"
     CDS             complement(5250..5801)
                     /locus_tag="KRH23_003555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHS5226825.1"
                     /translation="MSINTVIAKNLNRLRNERNLSLGQLAELSGVSKVMLSQIEKGDS
                     NPTVNTIWKIASGLNVPYTAILEQPQNETFIVSKTDIDVQVSENKDYRLYCYYPNTPT
                     RNFELFQMELEEGHSYTSVGHSEKSQEYIMIIEGQLKLEVNDSIYQLRENDSICFSAE
                     SIHTYHNQGEKTLKAVIINYYPV"
     gene            5992..6954
                     /locus_tag="KRH23_003556"
     CDS             5992..6954
                     /locus_tag="KRH23_003556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent cysteine synthase family protein"
                     /protein_id="HHS5226826.1"
                     /translation="MRVLNNVTEAIGNTHMLHLSKIADEFGVQGNIYAKMEYLNPGFS
                     KKDRVALQMITEAENAGLLVPGQAVVELTSGNTGTGLAIACACKGYKFIACMSKGNSM
                     ERARMMKALGAEVVLVDQMPNSVHGQVSGEDLALVEIEAQKIAKERNAFRADQFNLEA
                     CNHAHEKYTAEEMWEQLDGNIDVFVDFLGSGSTFAGCSKTLKKHNSSIKCYVVEPETA
                     AIYSGKEITEQGHKIQGGGYSMDLPLVDKKLIDGYIQVTDEEATDVARKLAKLEGVFA
                     GFSSGANVCAAIKLLKSSEKGKNIVLTLNDSGLKYLSTDLYEEL"
     gene            7249..9093
                     /locus_tag="KRH23_003557"
     CDS             7249..9093
                     /locus_tag="KRH23_003557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphoryl diester phosphodiesterase
                     membrane domain-containing protein"
                     /protein_id="HHS5226827.1"
                     /translation="MQKRILRNFIFTGKNILSKLVFIIKYNFSTLILFELFHKGLALF
                     FIWPSIRYIFDILIKSLHIVYLNMDNFIKVLTNPMSIVLIILSVIILAFYAFFEFTSV
                     IICLNKSIKYEKIGLFELFKISFENSIKLLYPKNILLFIFVILIIPLVNTVLISGFIG
                     KIQIPEYILDYIKSDIILNIIYMIFLLIIYISVIRWIFSIHEITLNTENFKRARKESV
                     NLIKGKIIRTIIYSLILSLVVAIIGYAIYHSGIIFIGIWTKYCTDMEFLKNVFINRCI
                     AFEEYFRLILSIFIFILDIGFISATYYQYKGVSISKNNIKKEKKSISKIVFNLVLILL
                     ISYIESVAFSSHINGMFNTSFSFYTTTIAHRAGAEMAPENTLAAIEEASHAKADYAEI
                     DVQETKDGELIVLHDSNFKRTTGVDKNVWDVNYNEVKTYDAGSFYYYGKGYYDEKFVG
                     EKIPTLKEMIKYSKGKVKLLIEIKLNGHEKGDVVKKVVQLIKENNFENQCIVASMDKA
                     ILQKVKKLDENLLTCYFMAIAYGDFSKLNYVDIYGIESTFVNKTVIEKIHKMNKKIFV
                     WTVNSDSLIEKMLDLNVDSIITDNPYLIESAIYWKKNGFISQVSDYLF"
     gene            9415..9999
                     /locus_tag="KRH23_003558"
     CDS             9415..9999
                     /locus_tag="KRH23_003558"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016407 - acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HHS5226828.1"
                     /translation="MTEREKMLAGELYDCGDIELLTQWHKAKDLVRDYNQTDSSDLEK
                     KEKILNELLGGKGKNLWITAPYYVDYGNNIYFGNNCEVNMNCTFLDDNKIIIGDNALI
                     APNVQIYTAFHPTNAGDRFGNAKEDGSFEFCKTQTAPVTIGDNVWIGGGAIIMPGVTI
                     GDNVVIGAGSIVTKDIPSNMIAYGNPCRIIRENK"
BASE COUNT         3922 a         1079 c         1536 g         3827 t
ORIGIN      
        1 taataaaaaa gatattacat taatatgaaa atataggaga ttagaagtgt ttgataatta
       61 cagtacatgt tagatatatc attgtaaatt aacataactt tgaatataat aatgttcaga
      121 aggcaatatt tttgaggtat gaatccaata atatagtctt atgattgtag atatcaaaaa
      181 atataagtta ctaggaatac gttttgtaga tttatatatg attaataact aaagctataa
      241 ataaacaaaa taaaaagagt atgtttcaac ctatagcttt tagatttaaa atatactctt
      301 ttattaatta tagttgtata aattaaccat aatatataat taaaattttt attataatta
      361 tatattaggt tcttcaatta gttttccaca tacatatcta tgaatgatat ttctatcatc
      421 accaacatag ataaatcttt caagtctttc aagtatagaa taattgtcat gatttaaatt
      481 tgaatcatca ataatcaatg catcaaaatc ataatcttct tcaaagctac caacttttcc
      541 aaagaaactt ccaccacttt tggttgcaat ataaaaagcc tcagataaag ataagaaatt
      601 atacttctta ccagaattaa cccaatataa tttagataat tgtattgcag ataccattgc
      661 tttaaatatt gacaatgtat gtccaccgct tatatctgat ccaagtgcta atctaatatt
      721 attatcgatt aattttctga taggcatagc accactacca acattaaagt tagaagctgg
      781 acagtgaact gccataacat tattttctct cattaaatct atttcatcct gagaacaatg
      841 aacacaatga gccattaaag taggagtttg accaaataaa ttatatctat tatatgcatc
      901 tccatagaat ttagattcag gttctagact tctaacccat tcaatctcat cataattttc
      961 agataagtgt gattgaatag gaatattata ttttaaacat aaatctccta aaccttttaa
     1021 aagttcactt gtacagcttg gtataaatct aggtgttatt attggtttta caatagaatc
     1081 tgtatcacta tacttattta taatttcttc tgtatcagca atagaatcca gagtgttttc
     1141 taataaagta tcagggcaat tcatattcat atttacttta ccaacgtatg ctccaagacc
     1201 aacttctttg aatatatcca taagtttcat agaggattct ttatgtactg ttgcaaacac
     1261 tgctattctt gtagttccag atttccaaag ttcttttaca aattttttat acatttttgt
     1321 tgcatattct atatctttat aatttgattc ttctggaaat gtataagttt caagccatgg
     1381 caaaagctct ttatccatag ccattccaag atttttaaat tgagaggcat gggcatggag
     1441 gtcattcata ccaggtatta taagcttatc agtgtaatct actactttta ggtttttgta
     1501 ttccttaggt atctctttaa atattccctt tactttacct ttttccagta taatataact
     1561 attttcaaat actgtgaaag tttctgaagt ttttgtaaaa attatatttc cttttaatac
     1621 ttttaacata taggtctcct tagttttaaa tttgttttaa tatatgtagg taaaattttg
     1681 ttttacaaat caaaatttta ccacatgtat tatatcaaat ctaaactata aatactatta
     1741 gataatagca aatattagtg aaatacagtt gtttactatt attatatata actgacattt
     1801 aagtgacatt taagaaaaat ataatgccta cttacataaa atggaatgtt atttaaagag
     1861 aactttgatt atattttcag aagctttttt atccatatcg tttaaaatat gagaatatct
     1921 atttatagtt atttttatat tagtatgtcc taatctttca gagatgattt ttatattagt
     1981 tctagctaga agaagaacta ttagaataga taatatagta agtatttaca aatatgtagg
     2041 tgttcttaaa ttgataaatt attccatttt aattttatag tttgaatttt atgatataat
     2101 aaaaatatat aaattttgca gtgagcgata tttttgataa agtagggttt aacagttgca
     2161 atgtaaggga ttgagggtgt gtgataaatg ttatcaattg cactactcat ggttcactgc
     2221 aaatttgaga gagttgtatg tgtgtaagta ctgaaaatac ttagtttatt ttggggtttt
     2281 atattaacta agtggtatgt aaatgctctt gtcgcagttg ctcctgaaat tattaatgtg
     2341 ttttatatta actaagtggt atgtaaataa aacaaaagga gtggtaaaaa tggctaagaa
     2401 aaaagtttta tattaactaa gtggtatgta aatctatgac gtaaatagtc tataccctta
     2461 tgtgatgaag gttttatatt aactaagtgg tatgtaaatt ggttgcgatt ggattattag
     2521 tagctggact tgtacatgtt ttatattaac taagtggtat gtaaattttt aaatatacca
     2581 agatttccta aaaaagtaga aaaagtttta tattaactaa gtggtatgta aatatcaatt
     2641 ctatttttat cagaaagcgt tgaacgagga gttttatatt aactaagtgg tatgtaaatt
     2701 ggatagatgc agaggctgac aaaactaaag tagtaagttt tatattaact aagtggtatg
     2761 taaatgagcc tgtcatacct gctatgaaaa catgctcgtc tgtgttttat attaactaag
     2821 tggtatgtaa ataaatttct tgctatttta cagtcattgt cattgtcgcg ttttatatta
     2881 actaagtggt atgtaaattt tttaattatt atgtcatcac ctagtgtaac cttatgtttt
     2941 atattaacta agtggtatgt aaatcacatt ggcgttgaag ctgttagcaa agcattaaaa
     3001 ggttttatat taactaagtg gtatgtaaat gtagcctatt gtttggcttc ctgacatttc
     3061 gtaagagttt tatattaact aagtggtatg taaattttta actatattaa ataagcgaat
     3121 aattaaaagg ggttttatat taactaagtg gtatgtaaat tttaaatggt gtgaatggtg
     3181 aaaggcacac aacacgtttt atattaacta agtggtatgt aaatcttcct gtaggtgcta
     3241 ccattaatac atttttaccc tgttttatat taactaagtg gtatgtaaat aggagataac
     3301 ttctattaaa gataactttg atgtgggttt tatattaact aagtggtatg taaatatgta
     3361 aagtttagca aattcaatag tatccatatt gtgttttata ttaactaagt ggtatgtaaa
     3421 ttggacacaa caaaaatttt tcaaaccttt taaaagagtt ttatattaac taagtggtat
     3481 gtaaataatt tctgtgctaa aaatttagtt acagaatata aagttttata ttaactaagt
     3541 ggtatgtaaa tcctgtagca ccttttatta tattttgaac gctaccacgt tttatattaa
     3601 ctaagtggta tgtaaatagt gaatgtgacc aattttgtga cgaattatca gaggttttat
     3661 attaactaag tggtatgtaa attagaaaat aacgtcagta gtattagcag gtaaatctaa
     3721 agttttatat taactaagtg gtatgtaaat cttgttaatg caaataaaca acatagcact
     3781 attaatagtt ttatattaac tatgcggtat gtaaataggg tttctgataa aatcttcaaa
     3841 catgtaaaat atgtgtttta tattaactat gaggtatgta aatcttatac ttagttagaa
     3901 ctatatatcg acacaaatat gctttatatt aactatatgg tatataaatt gcaattttta
     3961 ttcgttgtcc aatcgctttg aaatttgttt tatattaact atgtggtatg taaatttgca
     4021 acaagtatag gtaaaatacc ccaataattt atacagcatt ttatccttta aaatataatt
     4081 attttttatc atttgtagta aataattacc agataatatt gactttagtt ttaatgatta
     4141 aaatataaaa gtagaataat tataaaaagt attgaaaaat ttataaatat atataataaa
     4201 acttaatgac aagatattag atataaaaaa taattacctt ataaatagat tgaaatttat
     4261 gaatattcat actataattt aaatataagg agatgccctt tgaaaataaa aattaaaaaa
     4321 tatttaatgc tactacaata ggaactagaa ctacacttaa taaatataca gaaattagat
     4381 ttggctcaat ataaaataca aatatagaat ttaggtgttt tttatgaaaa aatttttata
     4441 tgctttatat agtttcattg ttattatagc taattttaga ttaaaagaaa aaaattataa
     4501 ctttatttta ttagcaatct tttttatact gctgttaatt caaaatggag ttttaaaaac
     4561 aggttatcaa aatagagcta cattttatca agataattat tttaatggag aggataaaaa
     4621 tgataagata aaatttatga ctataaagat ttttatattt ttgtcattac cattatgttt
     4681 taatatacta ttcaattatt taacctctta aattatattt agatatagga gtcttatgat
     4741 aaaagtaagc ttatgtgtta tttgtagtaa atataaagtg cgtatagtga taaaacaaaa
     4801 gtttcatata aatgaagaaa aaaatataaa ataatttatt taactactta aaaataaact
     4861 aaaggggata ataaaatagc ttttaggtta tggtaataaa ggtatttaaa aagagtgcat
     4921 aagcactcca attgtgagaa atacatacac aaatcattat tacaacaatg aaaaatgtac
     4981 atataagaga cgttttgtat ttgttttaag tgataatatt ttaatactaa ctaaataatt
     5041 atcacaatag taaaaaagaa aaaggagtat tttgtactcc atttgtcaaa aatataaaac
     5101 ttttatataa gcttattata acataattga taaaagtgta aagatatata atgaatttat
     5161 aaagaaaaat aaaataaaaa agataaatcc taatcaaagg atttatcttt ttgtatagaa
     5221 aataattatt ctattattaa atggcatggc taaactggat aataatttat tattactgct
     5281 ttcaatgttt tttctccttg attatggtat gtatgaattg attcagctga aaaacaaata
     5341 gagtcatttt ctctaagttg ataaatagag tcatttactt ctaattttaa ttgaccttct
     5401 ataatcataa tatattcctg tgatttttca gaatgaccaa cagatgtata actatgacct
     5461 tcttctaatt ccatttgaaa taattcgaag tttctagttg gtgtattggg ataataacaa
     5521 taaagacgat aatctttatt ttctgaaact tgtacatcta tatcagtttt tgatacaata
     5581 aaagtttcat tttgaggttg ttccagtatt gcagtatatg gaacatttag tccacttgca
     5641 attttccaaa ttgtgtttac tgttgggttt gagtctccct tttcaatttg cgaaagcatt
     5701 actttactta cgccagataa ttcagcaagt tgacctagac ttaagttacg ttcattacgt
     5761 aatctattta aatttttagc aataacagta ttaatactca tagtagctcc ttaaaatgta
     5821 aattattgac aaatataatt tacgaatgta taatttattt aacattattt ataatttaca
     5881 aatgtataat ataatgaacg ttaaatacac tgtacatccg taatataaat tatactgcat
     5941 aaagagttgt ttttcaacgg atgatagttg agagattaag ggggaattgt aatgcgtgta
     6001 cttaataatg ttacagaggc tataggaaat actcatatgt tacatttatc caaaatagca
     6061 gatgaatttg gagttcaagg taatatttat gcaaagatgg aatacttaaa tccgggattt
     6121 agtaaaaagg accgtgtagc attacaaatg attaccgaag cagaaaatgc aggtttatta
     6181 gttccaggtc aagcagttgt ggaattaaca agtggtaata ctggaacagg actagcaata
     6241 gcttgtgcat gtaaaggata taaatttata gcgtgtatgt caaaaggaaa ttctatggaa
     6301 agagcaagaa tgatgaaagc tttaggtgct gaagtagttc ttgtagacca aatgcctaat
     6361 tcagttcatg gacaggtatc tggtgaagat ttggcacttg tagaaattga ggctcaaaaa
     6421 atagcaaaag aaagaaatgc atttagagca gatcaattta atttagaagc ttgtaatcat
     6481 gcacatgaaa agtatacagc agaagaaatg tgggaacaat tggatggaaa tattgatgta
     6541 tttgtagatt ttcttggaag tggtagtact tttgcaggat gttcaaaaac acttaaaaaa
     6601 cataattctt ctatcaaatg ttatgttgtt gaacctgaaa cagcagcaat ttattcaggt
     6661 aaagaaataa ctgagcaagg gcataaaata caaggtggag gatattctat ggatttgcca
     6721 ttagtagaca agaaacttat tgatggttat attcaagtta cagacgagga ggcaactgat
     6781 gtagcaagaa aattagctaa attagaaggt gtatttgcag gattttcttc aggggcaaat
     6841 gtatgtgcag caattaagtt attaaagagc agtgaaaaag gaaaaaatat agttttaact
     6901 cttaatgata gtggtttaaa atatttaagt actgatttat atgaagaatt gtaataatag
     6961 cacaatagtt atgcaatgtt ttttaaatta agtatataga tttaaattat aaaaagtatc
     7021 tcaatgtaat ttttgaaagt tataaaggag atactttttt attttgtaaa tatggagtat
     7081 cctacttata agtattaagc tatatagata ttgatgatta gctatgcaat aaaaaagagt
     7141 atgtgttttt gcatttatac atcataactt ggaataatac atattaatgt tctaaatgta
     7201 tttaaaacat atgataaaat tagaacaaac agatacaagg agataaacat gcaaaagaga
     7261 attttaagaa attttatatt tacgggtaaa aatattttaa gtaaacttgt ttttataata
     7321 aaatataatt ttagtacatt aattttattt gaattatttc ataaaggatt agccttattt
     7381 tttatatggc catctattag atatatattt gatattttaa taaaaagttt acatatagtc
     7441 tacctaaata tggataattt tataaaagtt ttgaccaatc ccatgtcaat agttctgata
     7501 atactatcag ttataatact agctttttat gcattttttg aatttacctc tgtaattatt
     7561 tgtttaaata aatcgataaa atatgaaaaa atagggttat ttgaactctt taaaatatca
     7621 tttgagaact ctataaaatt gttatatcct aaaaatatac tattatttat atttgtgata
     7681 ttaataattc cattagtaaa tacagtttta atttcagggt ttataggaaa aatacaaata
     7741 ccagagtaca tattagatta tataaagtct gatataattt taaatataat ctatatgatt
     7801 tttcttttaa taatatatat ttcggttatt agatggattt ttagcattca tgagataact
     7861 ttaaatacag aaaattttaa aagagcaaga aaagaaagtg ttaatcttat aaagggaaag
     7921 attataagaa caattattta ttcattaata ttatctttag tagtagctat tattggatat
     7981 gcgatttatc atagtggaat tatatttata ggcatatgga ctaaatattg tactgatatg
     8041 gaatttttga agaatgtatt tataaataga tgtattgcat ttgaagaata ttttagattg
     8101 attttatcaa tattcatttt tatattggac attggattta tctcagcaac ttattatcaa
     8161 tataaaggag taagtatttc taaaaataat attaaaaaag agaaaaaatc tatatcaaaa
     8221 attgttttta atttagtatt aatattattg atttcttata tagagtcagt tgcattttct
     8281 tcacatataa atggtatgtt taatacgtca ttttcatttt atacaacaac aattgctcat
     8341 agagcaggag ctgaaatggc tccagagaat actttggcag caatagaaga agcttcacat
     8401 gctaaagctg attatgcaga aatagatgtt caagaaacta aagatggaga acttattgta
     8461 cttcatgatt caaactttaa gagaactaca ggagtagata aaaatgtttg ggatgtaaat
     8521 tacaatgaag taaagacata tgatgcggga agcttttatt attatggaaa aggttattat
     8581 gatgaaaagt ttgttgggga aaagatacca acactcaaag aaatgataaa atattctaaa
     8641 ggtaaggtga aattattaat agaaataaaa cttaatggac atgaaaaggg agacgtagta
     8701 aaaaaagttg ttcagttaat taaagaaaat aattttgaaa atcaatgtat agttgcatct
     8761 atggataaag ctatattaca aaaagtaaaa aaactggatg agaatttact gacatgctat
     8821 tttatggcaa ttgcatatgg tgatttttca aagttaaatt atgttgatat atatggaatt
     8881 gaatcaactt ttgttaataa aacagtaata gaaaagattc ataaaatgaa caaaaaaatc
     8941 ttcgtttgga ctgttaatag tgacagttta attgagaaaa tgcttgacct aaatgtagat
     9001 agtattatta cagataatcc ataccttata gagagtgcaa tttattggaa gaaaaatgga
     9061 tttattagtc aagtgtcaga ttatttattt taaatattct ataattgtat tatccagtaa
     9121 aagagatatt attaaaatca ataatatctc tttttaacat aaataaggtt gttaaattaa
     9181 ggttattctt ataaaaattg tgcttatcag ctataaacaa ggaataaaag tgaaaaaatt
     9241 gctctgagat tattacagtt aaaagagttt taagatgaca gagagataga ttgtcaactg
     9301 tatatttaat aaatcttgtt atttattaaa ttttatataa gtaaaatata taaattaata
     9361 aatcttatgc tagaatatat atgaaaaaca atataaattt ggaggattaa aaacatgaca
     9421 gagcgagaaa aaatgttggc aggagaactt tacgattgtg gtgatattga gttgttaact
     9481 caatggcata aagcaaaaga cctagtaaga gattataacc aaacagattc ctcggatttg
     9541 gaaaaaaaag aaaaaatatt aaatgagtta cttggtggta agggtaaaaa cttatggatt
     9601 actgcaccgt attatgtaga ttatggaaat aatatttatt ttggaaataa ttgtgaagtc
     9661 aatatgaatt gtacgttttt agatgataat aaaattatca ttggggataa tgcactaatc
     9721 gcaccaaacg tacaaatata tactgcattt catccaacta atgctggtga tagatttggt
     9781 aatgccaaag aagatggttc atttgaattt tgtaaaactc aaacagctcc agttactatt
     9841 ggagataatg tttggattgg cgggggtgct attatcatgc caggtgttac tattggagat
     9901 aatgtagtta taggtgcagg aagtattgtt acaaaagata ttccaagtaa tatgattgca
     9961 tacggaaatc catgccgtat tattcgagaa aataaataaa gttaaatttt cttgcaaaat
    10021 ctcaaaaaac acctttctta ctttatacat agggtatttt ctaatacttt cacatccata
    10081 ttcatttgtt aaatttttat ggaatgtagt ttttatcatt tctatcttac attttcacta
    10141 tttttttata aaagtcattc ctttatagat ttatttataa tagtatatat tctatttgat
    10201 gtttgaataa gcacttattt ttaagtaaaa tactaacttt tagattagta ttttgctata
    10261 gtatgatgat taagtaagaa taaaatacta taatacataa agcttaacaa atataatttt
    10321 tattttactt agatattttc ttttgattag caatcaaaag tagt
//
LOCUS       DAEORM030000095        10158 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.101, whole genome shotgun sequence.
ACCESSION   DAEORM030000095 DAEORM030000000
VERSION     DAEORM030000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10158)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10158)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 10158)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10158
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.101"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            complement(131..769)
                     /locus_tag="KRH23_003559"
     CDS             complement(131..769)
                     /locus_tag="KRH23_003559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 transporter permease"
                     /protein_id="HHS5226829.1"
                     /translation="MKGLILKDLLNLKGNIKFILLFIIMFGFMSSLGDGNVNNFIGVI
                     IVLCTTMIVSTFSYDDLNKWDSYVLTMPINRNDIVLSKYLTMLIFSFIGVLVSLIVSV
                     TIGYFKNTLILNETLLINALILSISVCFGSLILPLIYKFGTERARLLMILCFLVPTLA
                     LLVFKSILENISSPISIEIILNTLVYSLPFVAILLFVISYFISSKIYSKKEV"
     gene            complement(769..1632)
                     /locus_tag="KRH23_003560"
     CDS             complement(769..1632)
                     /locus_tag="KRH23_003560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHS5226830.1"
                     /translation="MISMDAITIKNLNKTYKDFSLQDISFSVPKGSVMGFVGENGAGK
                     TTTLKAILNLISYDSGNIEIFGLDSKKNEKEIKEQIGVVFEGSNFHENLNTDHVSKIM
                     SKIYKNWNDTLFKDYLKKLRVPDNKLIKEFSKGNKMKLSIAVALSHKPKLLILDEATS
                     SLDPIVREEILDIFLDFIQDEEHSIILSSHITSDLDKIADYITFIHKGKIVFSENKDE
                     LIDTMGVLKCKPSDFDNLSREDYSYYRKSQFGYEVLLKDKHRFISRHPNCIVDNTSIE
                     EIMLFYVRGDK"
     gene            complement(1629..2003)
                     /locus_tag="KRH23_003561"
     CDS             complement(1629..2003)
                     /locus_tag="KRH23_003561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HHS5226831.1"
                     /translation="MNIVISNSSGKPIYEQITTQIKSMIISGELPEGSALPSMRLLAK
                     ELRISVITTKRAYSDLERDGFIETVTGKGSFVSSKNMDFVKEEQFRLIEEYLQKAVDT
                     AKSSDITYDELKDILFLLYKGE"
     gene            2370..2774
                     /locus_tag="KRH23_003562"
     CDS             2370..2774
                     /locus_tag="KRH23_003562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006276 - plasmid maintenance [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication/maintenance protein RepL"
                     /protein_id="HHS5226832.1"
                     /translation="MDKTLKKDLNQEYTESKSLVMNKSKYMNVCFKNYIKVVEGMYTK
                     RDLIPLKLINSMDKNNKIRKTLYELSCEFEYPKTSLSSLFTELKKMDFLQRVKNGEYM
                     INPHIAYKGSRADKESLLAEYNQIKRPNKVSK"
     gene            2791..3387
                     /locus_tag="KRH23_003563"
     CDS             2791..3387
                     /locus_tag="KRH23_003563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226833.1"
                     /translation="MSLKLDRNVLQWFDYVFENEKTSLRHYNFNCTLKEISSTSLNKV
                     AFILEKNNSKYWKLYFEIPAEVTLKLKQNIHPLFREYIYEQISLYNNNQIYNFVNSNI
                     LKVFNNIAIYQYNILENLYTIDFKKSFIDKCQYLLIGEKRLIDEDLYLIAKSKEVFDF
                     FNSDGTFNLTLSFDIQKNENLLDSLLELRKSIIINERI"
     gene            3424..6018
                     /gene="clpB"
                     /locus_tag="KRH23_003564"
     CDS             3424..6018
                     /gene="clpB"
                     /locus_tag="KRH23_003564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_process: GO:0009408 - response to heat [Evidence IEA];
                     GO_process: GO:0042026 - protein refolding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HHS5226834.1"
                     /translation="MDVEKMTLRVQKSLNEAYNEAVKNHNQQVDVIHLFSALINQEDG
                     LIPNIIEKMNISIDSLRNTVNFEIDKLPKVYGEGADSQGVSATRKINEVLIKAESISK
                     EFKDSYISVEHVMLAMMETESKSAVGKILKQYNINKNDFLNILSQVRGSQRVETQDPE
                     GTYDALARYGTNLVDLAKKNKLDPVIGRDEEIRRIIRILSRRTKNNPVLIGEPGVGKT
                     AIVEGLAERIVRGDVPEGLKDKIVFSLDMGALIAGAKYRGEFEERLKAVLKEVQSSDG
                     KIILFIDEIHTIVGAGKTEGSMDAGNLIKPMLARGELNCIGATTFDEYRKYIEKDKAL
                     ERRFQPVIAEEPTVEDTISILRGLKERFEIHHGVRIHDNAIVAAAKLSHRYIQDRFLP
                     DKAIDLIDEAGAMIRSEIDSLPTELDVVRRKLFTLETEREALLKENDDKSKSRLDDIQ
                     KEIAELKSKNDEMTAKYEKEKSQILDIKNLKAQLDEAKGKAEKYEREYDFNKAAEVKY
                     GEIPKLEEQIKQYEENMNDGSENSLLKEEVTEEEISSIVSKWTGIPVTKLVEGEREKL
                     LKLEDELHKRVIGQDEAVTAVSNAVIRARAGLKDERKPIGSFIFLGPTGVGKTELAKT
                     LARNLFDSEDNIIRIDMSEYMEKHAVSRLVGPPPGYVGYEEGGQLTEAVRRAPYSVIL
                     FDEIEKAHEDVFNMFLQILDDGRLTDNKGKTVDFKNTLIIMTSNIGSNYLLEAGGNIT
                     ETTNNLVMNEMKHRFKPEFLNRVDDIIMFKPLDQENIKKIIDIFMKDLKNRLKEKDIT
                     IEVTNSAKDVMVREGYDPVYGARPLKRYIGNTLETVIAKKLIAGDVYNGCTIVIDGKD
                     ENIEVLVK"
     gene            complement(6215..7642)
                     /locus_tag="KRH23_003565"
     CDS             complement(6215..7642)
                     /locus_tag="KRH23_003565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HHS5226835.1"
                     /translation="MTNSFKKDDNRKKITVLFVVIAMTFMATLDSSIINVALPVLASK
                     LNVSLASIEWVIASYSIIICSTLLFFGRLGDIIGKSRVFQVGTILFTSASLLCGLSNS
                     LTLLIVCRFIQGIGASAYMANNHGIITELFPKESRGKALGILVTAVAIGNMVGPSLGG
                     FILSIFDWNVIFFINIPIGLIVIFLNTKFLPNSKKSSENMDKTGAILQFLGTTLFFSA
                     LISAQQTGLLNPYILIALLLSIIFIILFLILEKKHPQPLLDLEIFRNFKFSLNLICAL
                     TSFICIASSSILVPFYLQSTMKLPPIQAGLFMILSPLILAIFSPIFGNISDKIKSEKI
                     ILIGLLVMSFGFFLMSRLKESSALILFVIYISIISIGQAIFQPANNALIMSSCSRSKL
                     GVVGSINSLVRNLGQVIGITISTTLLYNFMSIKAGYRVNDYVINNDKIFVFGMRNVYI
                     IVTLVCLIGAILIGFYLFKYNKNEQ"
     gene            7784..8680
                     /locus_tag="KRH23_003566"
     CDS             7784..8680
                     /locus_tag="KRH23_003566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HHS5226836.1"
                     /translation="MKDKNTYFNRKGQENFIDIFLKDDIKKGANFKRHWHEHLQIYYF
                     IDGIAYLECGLDNFKVVPGNIVIANSNELHYLESLSDNLKFYSIRIEPTFLFSNQVDL
                     LQTKYLAPLALNHIVFNNLIQNDSLILKCITTILDEYHNKEVGYELSIKANIYQLIVL
                     LLRSHIDKIYSEDEFIKRKYSLEKFECIFDLIEEKYMDKITLKELASHVNLSAHHFCR
                     TFKQITGKTTIDFINGIRLDKAIYYLKETDLNMTEIAMRCGFDSINYFSRLFKRNYNI
                     SPTKYRNEHREVSNVILKEDMK"
     gene            9345..9485
                     /locus_tag="KRH23_003567"
     CDS             9345..9485
                     /locus_tag="KRH23_003567"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226837.1"
                     /translation="MEKSNTTVTKKEKIEDIGMKLEHLLSEDITFYELLLEILYKEKE
                     EN"
     gene            complement(9482..9853)
                     /locus_tag="KRH23_003568"
     CDS             complement(9482..9853)
                     /locus_tag="KRH23_003568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHS5226838.1"
                     /translation="MESLGDRIANLRKELDINQKELATKVGITEASLSRYENNLREPK
                     SEIIVRLAKALETSTDYLLGVNDNTKISKEDKLIIENLSVSEKTKKLLEKIYSLEKED
                     REAIEKMIDNAYLKRFLKEEN"
BASE COUNT         4097 a         1150 c         1457 g         3454 t
ORIGIN      
        1 cttattaaat ataagtaata aaataataaa tacctagtag agattaatag ttgaaaaata
       61 aaatactacc aaaataaact cgatagtatt ttatttaaat acttaaatac agaaacatat
      121 atagtatatt ttatacttct tttttactat agatttttga tgatataaaa tatgaaatca
      181 caaatagtaa aatagcaaca aatggaagag aatatactag tgtattaagt ataatttcta
      241 tagaaatagg tgaactaata ttttctaaaa tacttttaaa aactaataaa gctagtgttg
      301 gaactaaaaa gcataaaatc attaataaac gagctctttc tgtaccaaat ttataaataa
      361 gtggtagaat aaggctacca aaacatactg aaattgataa gattagtgca ttaataagta
      421 gtgtttcatt taatataagt gtatttttaa aataaccaat agttacacta acaataagtg
      481 aaacaagaac acctataaag ctaaatatta acatagttaa atatttactt aatacaatat
      541 cattgcgatt aataggcatt gtaagtacat aactatccca tttattcaaa tcatcatatg
      601 aaaatgttga aacaatcatt gtagtacata aaactataat aacacctata aagttattaa
      661 catttccatc tcctaaagaa gacataaagc caaacataat gatgaataaa agtataaact
      721 ttatatttcc tttcaaatta agtaaatctt ttaaaattag acctttcatt atttatcacc
      781 tctcacataa aataacataa tttcttctat agacgtatta tcaacaatac agtttggatg
      841 tcttgagata aatctatgtt tatctttaag aagtacttca tatccaaatt ggcttttacg
      901 ataatatgaa taatcctctc ttgaaaggtt atcaaaatca ctaggtttac attttaaaac
      961 tcccatagta tcaattaatt catccttatt ttcactaaat acaatttttc ctttatgtat
     1021 aaatgtaata tagtctgcta tcttatctaa atcacttgta atatgtgaag ataagataat
     1081 agagtgttct tcatcttgta taaaatctaa aaatatatct agtatttctt cacgaacgat
     1141 agggtcaagt gaactagttg cctcatctag tattaataat tttggtttat gagataaggc
     1201 tacagcaata ctaagtttca tcttattccc ctttgaaaac tccttaatta atttattgtc
     1261 tggtactctc aattttttta agtagtcttt aaataaggtg tcattccaat ttttatagat
     1321 tttactcatg atttttgaaa catggtcagt gtttaaattt tcatgaaagt tgcttccctc
     1381 aaatacaacc ccaatttgct ctttaatttc tttttcattt tttttactat caagaccaaa
     1441 gatttctata tttccactat cataagatat taaatttaaa attgctttta atgtagttgt
     1501 ttttcctgca ccattttcac ctacaaatcc cattacactc ccttttggta ctgaaaaaga
     1561 tatatcttgt aggctaaaat ctttataagt tttatttaaa ttttttatag ttattgcatc
     1621 catacttatc attctccttt atataataaa aataaaatat cttttaattc gtcatatgta
     1681 atatcactac tttttgctgt atcaactgct ttttgtaggt attcttcaat taaacgaaat
     1741 tgttcttctt tgacaaaatc catgttttta ctagatacaa aactgccttt accagtaact
     1801 gtctcaataa atccgtctcg ttctaaatcg ctatatgctc gttttgtagt aattacactt
     1861 attctaagtt cttttgccaa tagtctcata cttggaagag ctgagccttc tggtaactct
     1921 ccacttataa tcatactttt aatttgtgta gtaatctgtt catatattgg cttcccactc
     1981 gaattactaa taactatatt caataagaca cctccttaaa ttgtatatat agtatatata
     2041 cattatataa atatatatat aatatgtcaa ctgattttag aaaaaactaa ttgccaatat
     2101 tatacattta ataaatgtaa tgtattttat gaaagtctgc catattaaat agatataaat
     2161 ttttttaaaa aatttataaa tattgttcaa aaatcctgcc aataaattgg aaatactaaa
     2221 ttaaaaaaat aataaagttt agcttatagc taaataaaag tttacttata agctgaactt
     2281 tttgcgtttt cagttttgac atacatattt ttttgtaata tatttatatt atcaattaga
     2341 gataaggaga gtgagaagag atatttaatt tggataagac attaaaaaag gatttaaatc
     2401 aggaatatac agagagcaaa agtttagtta tgaataaaag taagtatatg aatgtttgtt
     2461 ttaagaatta tattaaagta gtagaaggaa tgtatactaa gagggattta attccattaa
     2521 aattaataaa ctctatggat aaaaataata agattagaaa aacattatat gaattatctt
     2581 gtgaatttga atatccaaaa acttctttat cttcattgtt tacggagctg aaaaaaatgg
     2641 attttttaca aagagtgaaa aatggtgagt atatgataaa tccacatata gcatataaag
     2701 gtagtagagc tgataaagaa agtttattag cagaatataa tcagataaaa agacctaata
     2761 aggttagtaa ataaggaaga aggtttttat atgagtttaa aacttgatag aaatgttcta
     2821 cagtggtttg actatgtatt tgagaatgaa aaaactagtt tgagacacta taattttaat
     2881 tgtacactaa aggagattag ttctaccagt ttgaacaaag tagcttttat tttagaaaaa
     2941 aataactcta agtactggaa gctttatttt gaaataccag ctgaagttac tttaaaactt
     3001 aagcaaaaca ttcatccttt atttagggaa tatatatacg aacaaatatc actgtataac
     3061 aataatcaaa tttacaattt tgtaaattca aacatattaa aagtgtttaa taatattgct
     3121 atttatcaat ataatatttt agaaaatcta tacactattg attttaaaaa gagttttata
     3181 gataaatgtc agtatttatt aataggtgaa aaaagactta tagatgaaga cttgtattta
     3241 atagcaaaat caaaagaagt attcgatttt tttaattcag atggaacatt taatttaaca
     3301 ttgagtttcg atatacaaaa aaacgagaat ttacttgata gtcttttaga gcttagaaaa
     3361 tcaataatta taaatgagag aatttaattt atttggatat aatattaaaa tggagggatt
     3421 tatatggacg tagaaaaaat gactttaaga gttcaaaaaa gtttaaatga ggcttataac
     3481 gaagcagtaa aaaatcataa ccaacaagta gatgtaattc atcttttctc agcacttatt
     3541 aatcaagagg atggattgat accaaatata atcgaaaaaa tgaatatatc aattgattct
     3601 ttgagaaata ctgtaaactt tgaaattgat aagcttccaa aggtatatgg agaaggtgct
     3661 gactcacaag gagtatcagc tactagaaaa ataaatgagg tgcttataaa ggcagagagt
     3721 atttctaaag aatttaaaga ttcatatata agtgtagagc atgttatgct tgcaatgatg
     3781 gaaacagaat caaaatcagc tgttggtaaa atattaaaac aatataatat aaataagaat
     3841 gactttttaa atattttatc acaagtgaga ggtagtcaaa gagtagaaac acaagaccca
     3901 gaaggcacat atgatgcact tgctagatat ggaacaaact tagtagattt agccaagaaa
     3961 aataaattag accctgtaat tgggagagat gaagaaataa gaaggattat aagaatttta
     4021 tcaagaagaa caaaaaataa tcctgtattg attggtgagc caggtgtagg taaaactgca
     4081 attgtagaag ggttagcaga gagaatagta agaggagacg tcccagaagg tttaaaagat
     4141 aagattgtat tctcacttga tatgggagct ttaattgctg gtgcaaaata tagaggtgaa
     4201 tttgaagaaa gattaaaggc agttttaaaa gaagttcaaa gttctgatgg aaaaattata
     4261 ctgtttatag atgagattca tactattgtt ggagctggta aaacagaagg ttcaatggat
     4321 gcaggtaatc ttattaaacc tatgcttgca agaggtgaat tgaactgtat tggtgcaact
     4381 acttttgatg aatatagaaa gtatatagaa aaagataagg ctcttgaaag acgttttcag
     4441 cctgtaattg cagaagaacc tactgttgaa gatacaatat ctatacttag aggtttaaaa
     4501 gaaagatttg agatacatca tggagtaaga atacatgata atgctattgt agcagcagca
     4561 aaactttctc acagatatat acaagataga tttttaccag ataaagcaat tgatttaatt
     4621 gatgaagctg gagctatgat tcgtagtgaa atagattcat tgccaacaga attagatgtt
     4681 gttagaagaa agttatttac attagaaact gaaagagaag cattacttaa agaaaatgat
     4741 gataaaagta aatcaagatt ggatgatatt caaaaagaaa tagcagagtt aaaatctaaa
     4801 aatgatgaaa tgacagcaaa atatgaaaaa gaaaagagtc aaatattaga tattaaaaac
     4861 ttaaaggctc aattagacga agctaaaggt aaagctgaaa agtatgaaag agaatatgat
     4921 ttcaacaaag cagcagaggt taaatatggt gaaataccta agttagaaga acaaataaag
     4981 cagtacgaag aaaatatgaa tgatggttct gaaaattctc ttttaaaaga agaagttact
     5041 gaagaagaaa tatctagcat tgtatcaaag tggacaggta taccagtaac taaactagtt
     5101 gaaggagaaa gagaaaaatt acttaaacta gaagatgaac ttcataaaag agttattgga
     5161 caagatgaag cagttacagc agtttcaaat gcagtaatac gtgcaagagc aggattaaaa
     5221 gatgaaagaa aaccaattgg ttcatttatt ttcttaggcc ctacaggtgt tggtaaaact
     5281 gaacttgcaa aaactcttgc tagaaattta ttcgatagtg aagataatat aataagaata
     5341 gatatgtctg aatacatgga aaaacatgct gtatcaagac tagttggacc tcctccaggg
     5401 tatgtgggat atgaagaggg tggtcaactt acagaagcag ttagacgtgc tccttattct
     5461 gtaatactat ttgatgagat agaaaaagca catgaggatg tatttaacat gttcttacag
     5521 atattagatg atggtagact tactgataat aaaggtaaga cagtagactt taaaaatact
     5581 cttataataa tgacttctaa tataggaagt aattatctat tagaagcagg aggaaatata
     5641 acagagacta ctaacaattt agtaatgaat gaaatgaagc atagatttaa acctgaattt
     5701 ttaaacagag tagatgatat tataatgttt aagcctttag accaagaaaa tatcaagaaa
     5761 attatagata tatttatgaa agatttaaaa aatagattaa aagaaaaaga tattactatt
     5821 gaagttacaa attcagcaaa agatgttatg gtgagagaag gatatgaccc tgtatatgga
     5881 gcaagacctc ttaagagata tataggaaat acattagaaa ctgtaattgc aaagaaactt
     5941 attgctggag atgtgtataa tggatgtact atagttatag atggaaaaga tgaaaatatt
     6001 gaagttttag ttaaataata aaagaatcag ttgagcataa tatactaaat attttgctca
     6061 gctgattttt atttataaac tataggaaaa gaaatatttt atcaaattaa taaaacattt
     6121 ttaagtcaat atgtccaaat taaatttaac tcaaaggaag tattttagta agtttcttat
     6181 aatataatca taatttgaat ataattataa aaaactattg ttcattttta ttatatttaa
     6241 ataaataaaa gccaattaat attgcaccta ttaagcaaac aagtgtaaca ataatataaa
     6301 catttctcat tccaaataca aatattttat cattattaat cacataatca ttgaccctat
     6361 atccagcttt aatactcata aaattatata aaagtgttgt agaaatagta atacctataa
     6421 cttgtcctaa atttcttaca agggaattta tgcttcctac aactcctagc ttacttctag
     6481 aacagcttga cattatcaaa gcattgttag caggttgaaa tatagcttgt cctattgata
     6541 ttatcgatat ataaattaca aataaaataa gggcagaact ttctttcaat cttgacatta
     6601 gaaagaatcc aaaactcata acgagaagac caattaaaat aattttttct gacttaattt
     6661 tatctgatat attcccaaat ataggtgaaa aaatggctaa aatcaaaggt gatagtatca
     6721 taaataaacc tgcttgaata gggggaagtt tcatagtact ttgtaaataa aatggaacta
     6781 aaatacttga tgatgcaata caaatgaatg atgtaagagc acaaattaaa ttcaatgaaa
     6841 atttaaaatt tctaaaaatt tcaaggtcaa gaagtggttg aggatgtttt ttttctaata
     6901 tcaaaaataa tataataaaa ataattgata ataatagtgc aattaatata tatggattta
     6961 gtaatcctgt ttgttgagca ctaattagag cactaaaaaa taatgttgtt cctaaaaatt
     7021 gaagtatagc accagtttta tccatatttt ctgaagattt tttactatta ggaagaaatt
     7081 ttgtatttaa aaagattaca ataagaccga ttggaatatt tataaaaaat ataacattcc
     7141 aatcaaatat tgacaaaata aatcctccca aagatggtcc aaccatattt ccaatagcaa
     7201 ctgcagtaac tagaatccct agggcttttc ctctgctttc ttttggaaat aattctgtga
     7261 taattccatg attgtttgcc atgtaggcag aagcgcctat tccttgaata aagcggcaaa
     7321 ctataagtaa agttaaagaa ttacttaatc cacatagtaa tgaagctgat gtaaagagaa
     7381 tagtacctac ttgaaatact cttgatttac caataatatc tccaagtctt ccaaaaaata
     7441 atagtgttga acaaataata attgagtaac ttgctattac ccattcaata gatgctagag
     7501 atacatttag tttgcttgca agaactggga gagcaacatt tataatacta gaatctaatg
     7561 ttgccataaa agtcatggca atgactacaa ataaaactgt gatttttttt ctattatcat
     7621 cttttttaaa agagtttgtc atttttatta cctccttatt ataatgactg gcattatgtt
     7681 aatgtttaca atgatagtta cattttatat aatagcgata tgaaataatg aatacaataa
     7741 ctatattgct tataattagc actattttga tgagggggga ataatgaagg ataaaaatac
     7801 atattttaac aggaaaggtc aagaaaactt tatagatatt tttttaaagg atgacattaa
     7861 aaaaggagca aactttaaaa gacattggca tgagcatcta caaatatatt attttattga
     7921 tggtatagca tatcttgaat gtggattgga taattttaag gtagtgcctg gaaatattgt
     7981 aatagcaaac agtaatgaat tacattattt agaaagctta tcagataatt taaaattcta
     8041 tagtattcgt attgaaccca cattcctttt tagtaatcaa gtcgatttgt tacaaactaa
     8101 gtacttagca ccattggctt taaatcatat tgtatttaat aatttaattc aaaatgattc
     8161 tctgatttta aaatgtatta caactatact tgatgaatat cacaataaag aagttggata
     8221 tgagttatct ataaaagcta atatctatca attaatagta ctcttattaa gaagtcatat
     8281 tgataaaata tattctgaag atgaatttat aaaaagaaag tattctttgg aaaaatttga
     8341 atgtatcttt gatttgatag aagaaaaata tatggataaa attacattaa aagaacttgc
     8401 tagtcatgtg aacttgagtg cacatcactt ttgtagaaca tttaagcaaa taacaggtaa
     8461 gactacaatc gattttataa atggaatcag gcttgataaa gctatatatt atttaaagga
     8521 aacagattta aatatgacag aaattgctat gagatgtggc tttgatagca taaattattt
     8581 tagtcgctta tttaaaagga attataatat atctccaact aagtatagaa atgaacatag
     8641 agaagttagt aatgttattt taaaagaaga tatgaaataa ttcataaata tactttatag
     8701 aaaatatata tttttaaatc tttgagtttt tcttaataaa tattaataaa gtatagtaca
     8761 taaatgagta agactacttg tatagttaaa tgtgaaaatg agtatgaaag aatgcagtgt
     8821 ctatgaaaag tatattttaa tatgaaacta aaactggaaa aataagaata gcagaaaaaa
     8881 tgattatatt ataaatcaat ttttttgaga catctggctt agattctgaa agatatttaa
     8941 tcaaagaaat aaaactatta aataagcaag taaacagcta aaatagtatg atttttatag
     9001 aaaatttaaa tccatcctaa agaattaaaa gaaagtcaaa taaatataaa aaaattatat
     9061 atttataaaa aattttataa taaaaatcat cctgaaaaat atataaaaat agaaaaaaca
     9121 tacaagattc tacaataata gatttttttg ttattattac gagtttttta ttgcaactgt
     9181 agaataaaag tattattata taattaagat aattatctag ggaaattttg gataatcaaa
     9241 atatatttta taaaatcaaa atacaattac ataaacttta ttaaaaattt gttgggaatt
     9301 tctgactaac attaagaacg taagtttgtt gggggatggt atatgtggaa aagtcaaaca
     9361 ctactgttac aaaaaaagaa aaaattgaag atataggaat gaaattagaa catttattga
     9421 gtgaagatat tactttttat gaattattac ttgagatttt gtataaagaa aaagaagaga
     9481 attaattctc ttctttaagg aatcttttta aataggcatt atcaatcatt ttttctatag
     9541 cttctctatc ttctttttca agagaatata ttttttctaa gagctttttt gttttttcac
     9601 ttactgataa gttctctatg attaatttat cttctttgct tatttttgta ttatcattta
     9661 cgcctaataa ataatctgtt gatgtttcta atgcttttgc taatctaact attatttcac
     9721 ttttaggttc tcttaaatta ttttcataac gtgacaagct agcctcagtt ataccgactt
     9781 tagtagcaag ttctttttga tttatatcta attcttttcg tagatttgct attctatctc
     9841 ctaaactttc catatgtaca tcactcctta ccgaaattat aagttatttt gataaaaagt
     9901 aaaataaaat taccaaaaat ataaaaaaaa aaggttaaaa taataaaata tattgaaaat
     9961 taccatttgt atatgtataa tatgaattat acaaatggta atttgatgag aggtggtatg
    10021 ttgaaataag aaactgaatt aattaataaa tacatagaaa gttttgaaaa cctttaattg
    10081 aaatataaac aatatgtaca aaattttttg caagtaaaat taccaaatgt ataaaataaa
    10141 tcagtagcat agataatt
//
LOCUS       DAEORM030000096         9723 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.102, whole genome shotgun sequence.
ACCESSION   DAEORM030000096 DAEORM030000000
VERSION     DAEORM030000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9723)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9723)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 9723)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9723
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.102"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            66..1133
                     /locus_tag="KRH23_003569"
     CDS             66..1133
                     /locus_tag="KRH23_003569"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0045227 - capsule polysaccharide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HHS5226839.1"
                     /translation="MKNKLVYICIMSLLLFVVGCSNNPNKESTIKKDSKNNQSQVKEE
                     KREPVKKDITISFAGDVTMGNYKGSSYYGSFDHEFKRQGEDYNYFLKNVKPVFEKDDL
                     TVVNLEGPLTTASNAKEKKFAFKGKPGYVNILKSGSVEAVSIANNHSEDYFEEGMKDT
                     QFILDENKINYFGLGKDAVVDVKGIKVGLLGYNGLSTEYNEKNLKQMEDDIKSLKKKS
                     DVVVVYFHWGIELDYYPDKKQKDFAHYAIDKGADLVMGSHPHVIQGIEKYKNKYIAYS
                     LGNFCFGGNKNPSDTDSYIYQQTFTFSDNKLTSIKEPNIIPTSITSSSSRNNYQPKVL
                     DGSEKDRVLNKLEKISKDLNK"
     gene            1303..3204
                     /gene="cooS"
                     /locus_tag="KRH23_003570"
     CDS             1303..3204
                     /gene="cooS"
                     /locus_tag="KRH23_003570"
                     /EC_number="1.2.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016151 - nickel cation binding [Evidence
                     IEA];
                     GO_function: GO:0043885 - anaerobic carbon-monoxide
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0006091 - generation of precursor
                     metabolites and energy [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic carbon-monoxide dehydrogenase
                     catalytic subunit"
                     /protein_id="HHS5226840.1"
                     /translation="MACNTCKMCESADKKLESFVASKDVETAFHRTEDQKVKCGFGLQ
                     GVCCRLCSNGPCRVTPKSPRGICGADADTIVARNFLRAVASGAACYLHVVENTAKNLK
                     NVGITKGVVKGEKTLNQLAEMFGIESDEKYDKCIKVADKVINDLYKSRDDKMELVEKI
                     AYAPRVKKWKELGIMPGGAKSEVFDAIVKSSTNLNSDPVDMLVNCLNLGISTGLYGLT
                     LTNLLNDVMLGEPVIRMAPVGFNVIDPDYINIMITGHQHSTFANFQDRLKDEDVIKLA
                     QSVGAKGFKLVGCTCVGQDLQLRGEHYQEVFAGHAGNNFTSEAVLSTGAIDIVLSEFN
                     CTIPGLEPIADKYKVKMVCLDDVAKKANAEYIGLDRSKLDELSNTLIEKALESYKERR
                     GSIEIDIPKDHGFEQSLTGVSEKNLKAFLGDSWKPLINLIAEGKIKGVAAVVGCSNMT
                     AGGHDVNTVELTKELIKKDIIVLSAGCSTGGLENVGLMSPGAEELAGENLKEVCKTLG
                     IPPVLNFGPCLAIGRLEIVATELAAELGIDLPQLPLVLSAPQWLEEQALADGAFGLAL
                     GLPLHLALPPFITGGKLVTEVLTEKLKDLTGGHVIVNPDPKSSANQLEEIIIDRRKNL
                     GLKDVECNA"
     gene            3197..3670
                     /locus_tag="KRH23_003571"
     CDS             3197..3670
                     /locus_tag="KRH23_003571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HHS5226841.1"
                     /translation="MHRIFINKDLCTGCKSCVLACMLKHNKDYDMYTLDLENIDNDSR
                     GHIELDSKHNNPVPILCRHCDEPECVLACMSGAMHKDSESGIVSYDEEKCGSCYMCVM
                     SCPYGLLKPDDRSKQNILKCDLCKDEEYPRCVANCPSGAIELQKEENDELCSVRG"
     gene            3645..4871
                     /locus_tag="KRH23_003572"
     CDS             3645..4871
                     /locus_tag="KRH23_003572"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HHS5226842.1"
                     /translation="MNYVVLGASAAGINAVKTLRELDKDSNIVVISKDENVYSRCMLH
                     HVISEHRTLKQINFVDEDFMEQNNVKWIAGKTVKGIDINKKVVQTEDITVNYDKLLIA
                     TGASSAIPPIKNLRDGNFVYSVRNIDDIYKIKEKAQNSKNVVIIGAGLVGIDALVGLF
                     KYEQLNISVAFMEKYILDRQLDEYTASVYENKFKEKGVKFYPSASIQEIVLDNSKNVT
                     GVAFSNGEVLDADMVIVATGVKPNADFLDGTGIEYDRGITIDDMCQTTQKDIYAAGDV
                     VGKNAIWPLAVKQGIVAAYNMVGKDKKIEDEFAFKNSMNFMDIPTISIGMNTPVDDSY
                     KVLTRHGINDYKKFVFKDNVIYGAVIQGDISYVGVLTYLIKNKVEIYDLENRIFDVCY
                     ADFFNIKENGEFCYSV"
     gene            complement(5010..6197)
                     /locus_tag="KRH23_003573"
     CDS             complement(5010..6197)
                     /locus_tag="KRH23_003573"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HHS5226843.1"
                     /translation="MNITKNFLKDYLEKFGETPFLVRLKDEEEFLIGEGSPQFKVIVN
                     NDISKSELLKSTSLALGEAYINRDIEVEGDLFLTLNLLLKQIDKFNIDNSAVKHLLHS
                     SNSMRHQKKEIHAHYDIGNDFYSLWLDKTLSYSCAYFRNDNDTLYDAQVNKVHHILTK
                     LNLEEGMSLLDIGCGWGFLLIEAAKKYKIHGVGITLSEEQFKEFNARIKEENLQDYLE
                     VRLMDYRELKKSDLMFDRVVSVGMLEHVGRENYELFIKNVNAVLKDGGLFLLHYISGL
                     QESYGDPWIKKYIFPGGVIPSLREMIHICSDYKYHTIDVESLRLHYVKTLLYWQKNFS
                     ENLPKIKEMFDDKFIRMWDLYLCSCAAAFNTGIIDIHQILFTKGIKNDLPLTREYMYN
                     CSK"
     gene            6470..7294
                     /locus_tag="KRH23_003574"
     CDS             6470..7294
                     /locus_tag="KRH23_003574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HHS5226844.1"
                     /translation="MEVYALVGSSGTGKSFKALEFAYENDIEYIIDDGILIYKNKVLA
                     GISAKQANTTIEAVKRAIFYNLEHRQEVREAIKKENIRKILIIGTSKKMVNQIVERLS
                     IGRVYKFINIQDISTKYEIEIAKQARKEGNHVIPVPAVEIKSMASGLSINSLKRLFRK
                     GNNRNMVVLEKTIIRPTFSYIGKFYISADVIKQIIEYEVYNFGSIDRINKINIENCNN
                     FMNIFVSININDLETIKKIEDIQQTIKKSIEKMTLVNVQKIDINIHKIKKINFLQC"
     gene            7423..8688
                     /gene="gluD"
                     /locus_tag="KRH23_003575"
     CDS             7423..8688
                     /gene="gluD"
                     /locus_tag="KRH23_003575"
                     /EC_number="1.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-specific glutamate dehydrogenase"
                     /protein_id="HHS5226845.1"
                     /translation="MSGKDVNVFEMAQSQVKNACDKLGMEPAVYELLKEPMRVIEVSI
                     PVKMDDGSIKTFKGFRSQHNDAVGPTKGGIRFHQNVSRDEVKALSIWMTFKCSVTGIP
                     YGGGKGGIIVDPSTLSQGELERLSRGYIDGIYKLIGEKVDVPAPDVNTNGQIMSWMVD
                     EYNKLTGQSSIGVITGKPVEFGGSLGRTAATGFGVAVTAREAAAKLGIDMKKAKIAVQ
                     GIGNVGSYTVLNCEKLGGTVVAMAEWCKSEGSYAIYNENGLDGQAMLDYMKEHGNLLN
                     FPGAKRISLEEFWASDVDIVIPAALENSITKEVAESIKAKLVCEAANGPTTPEADEVF
                     AERGIVLTPDILTNAGGVTVSYFEWVQNLYGYYWSEEEVEQKEEIAMVKAFESIWKIK
                     EEYNVTMREAAYMHSIKKVAEAMKLRGWY"
     gene            8901..9491
                     /locus_tag="KRH23_003576"
     CDS             8901..9491
                     /locus_tag="KRH23_003576"
                     /inference="COORDINATES: protein motif:HMM:NF017390.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M56 family metallopeptidase"
                     /protein_id="HHS5226846.1"
                     /translation="MHFKSKDFHLKYLVLFLKIVYWFNPFIYIMEKYMDLDCELYCDE
                     RVLKNCTVQQKQEYVLTIVNSMKRSTNFSNKFVAGLNNQSNIRKRVMNMFSEKHKNGI
                     LMALSISLFSSITFFKFDSTSIIEENDFLERSRYTFEGRQEDMFVTIDFTYADAPIKL
                     RKEHEENCRVNGIVPKDSDSIEIIPRFYKDCMDLKK"
BASE COUNT         3783 a         1061 c         1760 g         3119 t
ORIGIN      
        1 aaaaatgtta tactctaaaa aagtatattt tatttaaaaa tttattaata caaaggagat
       61 ttactatgaa aaataaatta gtttacatat gtattatgag tctattgcta tttgtagtag
      121 gatgttctaa taatccaaat aaggaaagta ccattaaaaa agactctaag aataaccaaa
      181 gccaagttaa agaagaaaaa agagaacctg tgaaaaaaga tataactata agtttcgctg
      241 gtgatgtaac tatggggaac tataaaggtt catcatatta tggcagtttt gaccatgaat
      301 ttaaaagaca aggagaagat tacaattatt ttcttaaaaa tgtaaaacct gtatttgaaa
      361 aagatgactt aacagtggtt aatttagaag gtccacttac tacagcgtca aatgcaaaag
      421 aaaaaaaatt tgcatttaaa ggaaagcctg gatatgtaaa tattttaaaa tctggaagtg
      481 tagaggcagt aagtattgca aataatcatt cagaagatta ttttgaagaa ggaatgaaag
      541 atacacagtt tatattggac gagaataaaa taaattattt tggattaggg aaagatgctg
      601 ttgtagatgt caaaggaatt aaagtgggtc tattagggta taatggatta tcaactgaat
      661 ataatgaaaa aaatttaaaa caaatggaag atgatattaa gtccttaaaa aagaaatcgg
      721 atgttgttgt agtgtacttt cattggggga tagaattaga ttattatcca gataaaaaac
      781 aaaaagattt tgctcattat gctatagaca agggagcaga tttagttatg gggtctcacc
      841 cacatgtgat tcaaggaata gaaaagtata aaaataagta tatagcttat agtctaggga
      901 atttttgctt tggaggaaat aagaatcctt ctgatacaga tagttatata tatcaacaaa
      961 cctttacttt ttcagataat aaattaactt caattaaaga gccaaatata ataccaacct
     1021 caataacatc tagtagctcc agaaataatt atcaaccaaa agtattggat ggaagtgaga
     1081 aggatagagt tttaaataaa cttgaaaaaa taagcaaaga tttaaataaa taaaatgtaa
     1141 aaaaaaataa atatatatat ttattttaat aatttatatt ttgtttaggg tatggtaaat
     1201 cgtggtatta aataagtaga ttttaatagt taaattatag tcaattataa taaagctatt
     1261 taatctactt ttttaatata aaaatataag ggggaatttg taatggcttg taacacttgt
     1321 aaaatgtgcg aaagtgcaga caagaaatta gaaagttttg tagcttcaaa ggatgttgaa
     1381 acagcatttc atagaacaga agatcagaaa gttaagtgtg gttttggact tcagggggtt
     1441 tgttgtagac tctgttcaaa tggaccatgt agagtaactc ctaaatcacc aagaggtata
     1501 tgtggagcag atgcagacac tatagtagca agaaactttt taagagcagt agcatcagga
     1561 gcagcttgtt atttacatgt ggtagaaaat acagctaaga atttaaaaaa tgttggaata
     1621 actaaaggtg ttgttaaagg agaaaaaaca ttaaatcaat tagcagagat gtttggaata
     1681 gaaagtgatg aaaagtatga taaatgtata aaggttgcag acaaagttat caacgatttg
     1741 tataaatcaa gagatgataa aatggaatta gtagaaaaaa tagcttatgc acctagagtg
     1801 aaaaagtgga aagagttagg tataatgcct ggtggtgcaa agtcagaagt ttttgatgca
     1861 atagtaaaat catcaacaaa tttaaatagt gacccagtag acatgctagt taattgtttg
     1921 aacttaggta tatcaacagg attatatggt cttacactaa ctaatctttt aaatgatgtt
     1981 atgttgggag aaccagttat aagaatggct cctgtaggat ttaatgtaat agacccagac
     2041 tacataaata taatgataac aggccatcaa cattcaacat ttgcaaattt ccaagataga
     2101 ttaaaagatg aagatgttat aaaattagct caatctgttg gtgcaaaagg ctttaagcta
     2161 gtaggatgta catgtgttgg tcaagattta caattaagag gagaacatta tcaagaagta
     2221 tttgctggac atgcaggtaa caattttaca agtgaggctg ttttatcaac tggagcaata
     2281 gatatagttc tttcagaatt taactgtact ataccagggc ttgaaccaat agcagataaa
     2341 tataaagtaa aaatggtttg tttagatgat gttgctaaaa aagcgaatgc agaatacata
     2401 ggtttagaca gaagtaaatt agatgaactt agtaacactt taatagaaaa agcattggag
     2461 tcttataagg agagaagagg aagtattgaa atagatatac caaaagacca tggatttgaa
     2521 caatctttaa ctggtgtaag tgaaaagaac ctgaaagcgt ttttaggaga ttcatggaaa
     2581 cctcttatta atttaattgc agaaggaaaa attaaaggtg ttgcagctgt tgtaggatgt
     2641 tcaaatatga cagcaggagg acatgatgta aatactgttg aacttactaa agaattgatt
     2701 aaaaaagata taatagtact atctgcagga tgttctactg gaggattaga aaatgttggt
     2761 cttatgtcac ctggagcaga agaattagca ggagaaaact taaaagaagt atgtaagact
     2821 ttaggaatac caccagtatt aaactttgga ccatgtctag ctataggaag actagaaata
     2881 gtagcaacag aattagcagc tgaacttgga attgacctac cacaattacc attagtgctt
     2941 tcagctccac aatggttgga agaacaagca ttagctgatg gagcgtttgg tcttgccctt
     3001 ggcttacctc ttcatttagc tttacctcca tttataacag gaggaaaatt ggtgacagaa
     3061 gtattaacag aaaaattaaa agacttaaca ggaggacatg ttatagtgaa tccagaccct
     3121 aaatcttcag ctaatcaatt agaagaaata ataatagata gaagaaaaaa tttagggtta
     3181 aaggatgtgg aatgcaatgc atagaatttt tataaataaa gatttatgta caggatgtaa
     3241 gagctgtgta ctagcatgta tgctaaaaca caataaagat tatgacatgt acactcttga
     3301 tttagaaaat atagataatg atagtagagg gcatatagaa ttagatagta aacataataa
     3361 tccagttcca attctttgta gacactgtga tgaacctgaa tgtgtattag catgtatgag
     3421 tggtgcaatg cataaagata gtgaaagtgg aatcgtttca tatgatgaag agaaatgtgg
     3481 ttcatgttat atgtgtgtaa tgtcttgtcc atatggatta ttaaagccag atgatagaag
     3541 caagcagaac atacttaaat gtgatttatg taaagatgag gagtatccta gatgtgtagc
     3601 taattgccca agtggagcaa ttgaattaca gaaggaggaa aatgatgaat tatgtagtgt
     3661 taggggctag tgcagctggt ataaatgcag taaaaacatt aagagaatta gataaagatt
     3721 caaatatagt agtaatttct aaagatgaaa acgtatattc aagatgtatg ttgcatcatg
     3781 ttatatctga acacagaact ttaaaacaaa taaattttgt tgatgaagat tttatggagc
     3841 aaaataatgt aaaatggatt gcaggtaaga ctgttaaagg tatagacata aataaaaagg
     3901 tagttcagac agaagacatt actgtaaatt atgataaact tttaatagct acaggtgcat
     3961 cttctgctat tcctcctata aaaaatttaa gagatggaaa ttttgtatat tctgtgagaa
     4021 acatagatga tatttataaa ataaaagaaa aagcacaaaa ttctaaaaat gtagttataa
     4081 taggtgctgg tttagttggt atagatgcat tagtgggatt atttaaatat gagcagttaa
     4141 atatttctgt agcttttatg gaaaagtaca ttttagatag acaattggat gaatatacag
     4201 catcagtgta tgaaaataag ttcaaagaaa aaggtgtaaa attttaccca agtgcatcaa
     4261 tacaagaaat tgtattggat aacagtaaaa atgttacagg tgttgcattt tcaaatggtg
     4321 aagttttaga tgcagacatg gtaattgtag ctacaggggt taaaccaaat gctgactttt
     4381 tagatggaac aggaatagaa tatgatagag gtataacaat agatgatatg tgccaaacaa
     4441 cacaaaaaga catatatgca gcaggagatg ttgtaggtaa aaatgctatt tggcctctgg
     4501 cagtaaagca aggaattgta gctgcctata atatggttgg aaaagataag aagatagaag
     4561 atgaatttgc ttttaaaaat agtatgaatt tcatggatat accaactatt tctataggaa
     4621 tgaatacacc tgtagatgat agctataaag tattaaccag acatggaatt aatgattata
     4681 aaaagtttgt ttttaaagat aatgtaatct atggagcagt tatacaagga gatatttcat
     4741 atgtaggtgt attaacttat ttaataaaaa ataaagttga aatatatgat ttagaaaata
     4801 ggatatttga tgtatgttat gcagactttt ttaatataaa agaaaatgga gaattttgtt
     4861 atagtgtata gtatatacgt gaagtaaggt ttataaatac agtaaatcaa taaatagagt
     4921 tattctaaaa taagaaaaat gacaaatctt atttagaaat agctctattt tttgcaatta
     4981 aatttaaatt atattcaatt tgtaaaatat tattttgaac aattatacat atactctcta
     5041 gttagaggta aatcattttt tataccttta gtgaaaagta tttgatgtat atctataata
     5101 ccagtgttga aagcagcagc gcaagaacaa aggtataaat cccacattct tataaactta
     5161 tcatcaaaca tttctttaat ctttggaaga ttctcagaga aatttttttg ccagtatagt
     5221 aaggttttta cataatgtaa tcttaaactt tctacgtcta tagtatgata tttgtaatca
     5281 ctacaaatat gtatcatttc tcttaggcta ggaataactc ctcctgggaa aatatatttt
     5341 tttatccaag ggtctccata agattcctgc aatccactta tatagtgaag taaaaacaat
     5401 ccaccatctt ttaaaacagc atttacgttt ttaatgaaaa gttcatagtt ttctctacca
     5461 acatgttcaa gcatcccaac gcttacaact ctatcaaaca taaggtctga tttttttaat
     5521 tctctatagt ccataagtct tacctcaaga tagtcttgaa ggttctcttc tttaattctt
     5581 gcgttaaatt ccttaaattg ctcttcgcta agtgtaattc caacgccgtg aattttatat
     5641 ttttttgcag cttctattag taaaaatccc caaccacaac caatatcgag aaggctcata
     5701 ccttcctcta aatttagttt agttaatatg tggtgaactt tattgacttg agcatcataa
     5761 agagtatcat tatcatttct aaagtatgca caagaataac taagtgtctt atctaaccat
     5821 aagctataaa aatcgttgcc aatgtcatag tgggcatgta tttctttctt ttgatgtctc
     5881 attgaatttg atgagtgcaa tagatgtttt acagctgaat tatcaatatt gaatttgtct
     5941 atttgtttta aaagtagatt taaagttaag aataaatctc cctcaacttc aatgtctcta
     6001 tttatgtagg cttctccaag tgctaaagat gtacttttta atagttcaga cttgctaata
     6061 tcattattta ctataacttt gaactgaggg gagccctctc caattagaaa ttcttcctca
     6121 tctttaagcc taactagaaa tggtgtttca ccaaatttct ctaaatagtc ttttaaaaaa
     6181 ttttttgtaa tattcatatt accagctcct tctaatgtaa atccagtaag tttccctgct
     6241 taaaatatat tatagtcctt tttttaaaaa agtaaaattt tttcaataaa ttttttattt
     6301 aaaggaaatt tattttttat aaagaaattt catgttgtag tatatttttt gcttataaat
     6361 tttggtactg gatataatat taaactgtta atgatataat aaatttaatc tataaagtaa
     6421 ataaaatttt gtaataaata gttaaagcta ttttataagg agatctatga tggaagtata
     6481 tgctttggtt gggtcaagtg gcacagggaa gagctttaag gctttagagt tcgcatatga
     6541 aaatgatata gaatatataa ttgatgatgg gattttaata tacaaaaaca aggttttagc
     6601 tgggatatcg gcaaaacaag caaatactac tatagaagca gttaaaaggg ctatttttta
     6661 taatctggag catagacaag aagttagaga agcaattaaa aaagaaaata taagaaaaat
     6721 tcttattatt gggacatcaa aaaaaatggt taatcaaatt gtagagagat tgtcaattgg
     6781 aagggtctat aagtttataa atatacaaga tataagtact aaatatgaaa tagaaatagc
     6841 aaaacaagct agaaaagaag gaaatcatgt aattcctgtt ccagcagttg agataaaaag
     6901 tatggcaagt ggtcttagta taaattcttt gaagagactt tttagaaaag gaaataatag
     6961 gaatatggta gttttagaaa aaacaattat aagaccaact tttagttata taggaaagtt
     7021 ttatattagt gctgatgtaa ttaaacagat tattgaatat gaagtataca actttggaag
     7081 cattgataga ataaataaaa tcaatataga gaattgcaat aattttatga atatttttgt
     7141 aagtataaat atcaatgatt tagaaactat aaaaaaaatt gaagacatac aacagacaat
     7201 aaaaaagtct attgagaaaa tgactttagt taatgtacaa aaaatagata ttaacattca
     7261 taaaattaaa aaaataaact tcctccaatg ttaaaaaata aactgagaaa atgatatact
     7321 aatttgcaat aaagtgtgct ataattaaac tgtaaattta ggaaatggtt ttttctaaat
     7381 ggagtataca taattataac gtatttataa gggggctttc aaatgtcagg aaaagatgta
     7441 aatgtcttcg agatggcgca atctcaagta aaaaatgcat gtgataaatt aggtatggaa
     7501 ccagcagttt atgaattatt aaaagaacct atgagagtta tagaggtttc aattccagta
     7561 aaaatggatg atggttctat aaaaactttt aaaggattta gatcacaaca taatgatgca
     7621 gtagggccaa caaaaggtgg aataagattc catcaaaatg tttcaagaga cgaagtaaaa
     7681 gctttatcta tatggatgac tttcaagtgt tctgtaacag gtataccata tggtggaggt
     7741 aaaggtggaa taatagtaga tccatcaact ttatctcaag gtgaattaga aagattaagt
     7801 agaggataca tagatggaat atataaatta ataggtgaga aagttgacgt tcctgcacca
     7861 gacgtaaata ctaatggtca aataatgtct tggatggttg atgagtacaa taaattaact
     7921 ggacaaagtt ctataggtgt tataactgga aagccagttg aatttggtgg ttctttagga
     7981 agaacagctg ctactggatt tggtgttgct gttactgcaa gagaagctgc tgctaaatta
     8041 ggaatagata tgaaaaaagc taaaatagct gttcaaggta taggaaacgt tggttcttat
     8101 acagttctta actgtgaaaa acttggtggt actgttgtag ctatggctga atggtgtaaa
     8161 tcagaaggtt cttatgctat atacaatgaa aatggtttag atggtcaagc tatgttagat
     8221 tatatgaaag aacatggtaa cttattaaac ttcccaggag ctaagagaat atctttagaa
     8281 gagttctggg cttcagatgt tgatatagta ataccagctg cattagaaaa ctctataact
     8341 aaagaagttg ctgaatctat aaaagctaaa ttagtttgtg aggctgctaa tggaccaact
     8401 actccagagg ctgatgaagt atttgctgaa agaggaatag ttcttactcc agatatatta
     8461 actaatgctg gtggagttac agtttcttac ttcgagtggg tacaaaactt atatggatac
     8521 tactggtcag aagaagaagt agagcaaaaa gaagaaatag ctatggttaa agcatttgaa
     8581 tctatttgga aaatcaaaga agagtacaat gttacaatga gagaagctgc ttacatgcat
     8641 tcaattaaga aagttgctga agctatgaaa ttaagaggat ggtactaaga tttactctta
     8701 ataaataata ggatataatt atttaagata taaaggggct gtacatagta cagcccttaa
     8761 attatgtggc ttacaatgaa gtaagctatt tttgttttaa cttataaata acttgataaa
     8821 ttatgtaatt tagaatgtat tttttaccac cacatgatta caaattagag gagttagatt
     8881 gaatttttag acatgaactt atgcatttta aaagcaaaga ctttcattta aagtatctag
     8941 tattattttt aaaaatagta tattggttta atccatttat atatataatg gaaaaatata
     9001 tggatttgga ttgtgaactt tattgtgatg agagagtttt aaaaaattgt actgtacaac
     9061 aaaagcaaga atatgttcta actattgtaa attcaatgaa aagaagtaca aatttttcaa
     9121 ataaatttgt agctggatta aataaccaat ctaatattag aaaaagagta atgaacatgt
     9181 tcagtgaaaa acataaaaat ggtatcttaa tggctttgag tataagcttg ttttcttcta
     9241 ttacattttt taaattcgat tcaactagta ttattgaaga gaatgatttc ttagagaggt
     9301 caagatatac gtttgaagga aggcaagaag atatgtttgt aacaatagat tttacatatg
     9361 cagatgcacc tataaaactt agaaaagagc atgaagaaaa ctgtagagtc aatggaatag
     9421 taccaaaaga ttcagattca atagaaatta ttcctagatt ttataaagat tgtatggatt
     9481 taaaaaaata agttagactt aatattgatg ttgatattat gaatttttta tatttaagca
     9541 attgaaaatt ttattataga ttcaatttta tatgtgttta agtatgaaat ttatagatag
     9601 ttgaaataat taaatatgat tgatgcatag gaatcattac taagctataa ttaattataa
     9661 gggagtttaa ataaattatg agttacacaa ttataaaatg ataaaaaata gttatctgtt
     9721 aca
//
LOCUS       DAEORM030000097         9620 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.103, whole genome shotgun sequence.
ACCESSION   DAEORM030000097 DAEORM030000000
VERSION     DAEORM030000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9620)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9620)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 9620)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9620
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.103"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            708..1229
                     /locus_tag="KRH23_003577"
     CDS             708..1229
                     /locus_tag="KRH23_003577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HHS5226847.1"
                     /translation="MDFKIRELINDITQDIIQTYKIQIPIVNINQVVDALGGKVIEDS
                     SLSGYSDGFIRKVDDSFEIVVSPYQPDTRKNFTIAHELGHLFLHMGYGIDDELWNSQD
                     GNQYFRSGNTNKEYQSNEFAAALLMPKHEYKRIMDENTVGNKVDTSKIAEYFNVSSYA
                     ASNRGKWLGYLQW"
     gene            1205..2791
                     /locus_tag="KRH23_003578"
     CDS             1205..2791
                     /locus_tag="KRH23_003578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226848.1"
                     /translation="MVRIFTMVDDKEYKTQNVNNVHNSAKNENAFNLKKYKEKLQENI
                     NTDIYEKEKEPNHPEVILFFSFDIANSSLYKNINYSGWAKVLSHIIRKLQYRVYENLK
                     AQLWRVLGDEVIFIIVLKNYDEIYKYIDIIFDILTSTAKDIKSGNIFSTLEGFSESEK
                     YLMKLQNIISLKGAAWIAIVSRNPNFNALENNEQYENISAMYDLSNNYKIFEFLGNDI
                     DAGFRISKQTCPERLVLSFELAYILSRKTDILSKLHIITYKKLKGIWKDKLYPIIWYH
                     NKGKNNDIEFDDSFSFDEIEENELVREYFFNKKGESKLLIDSFMFNSVDKALDKILID
                     RNLSDKIEKIGDVISKTNPSYDKNTIDKDYIKVDLMELHCVAVCYNKSTSKILIAKRS
                     DNRNNNASKWEFGCAKASLETSIINTIKDEYEKDFNINIEPITDCTRKDDCQPIPLAI
                     YQVKKSDGLHKGIITLAEIINDYDISKFEPTSKHNELAWIGEDELEDFNENTVPDFKE
                     TLKLAFKKLNENQLQESTNM"
     gene            complement(2855..3373)
                     /locus_tag="KRH23_003579"
     CDS             complement(2855..3373)
                     /locus_tag="KRH23_003579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Pycsar system effector family protein"
                     /protein_id="HHS5226849.1"
                     /translation="MDKKIDIAKFIVNRIDYYIEKSDNKASFLLLLNSAIIGFLFSGK
                     EKIMNHLSISNIRCLEMLFYIVILCIFVISIYFSIMVLKPRNSKIENEYKSIFYYKEI
                     ASLNNEQYKEAFENAFKDEENLINDALVQIKELSLICDKKMYNVKKSVEAFILGGIIL
                     FIYILVVVFNAI"
     gene            complement(3539..3886)
                     /locus_tag="KRH23_003580"
     CDS             complement(3539..3886)
                     /locus_tag="KRH23_003580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226850.1"
                     /translation="MDALVYERFVRAAFSIKLNNLINRSEDLGGLAEADIFRAANNLH
                     ELNEIKIGTGYAIAIFNNEILESCNVSDNDSNRMIELFDRSLIATSREEILDIIREYE
                     TYRGRYLTFNWKR"
     gene            complement(3982..4794)
                     /locus_tag="KRH23_003581"
     CDS             complement(3982..4794)
                     /locus_tag="KRH23_003581"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008745 - N-acetylmuramoyl-L-alanine
                     amidase activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HHS5226851.1"
                     /translation="MKICITVGHSILKSGACTSADGVVNEYQYNKSLAPVLADTFRKE
                     GHKVDVIICPEKQFKTKNEEKSYKIPRVNSGGYDLLIELHLNASNGQGKGSEVLYYSN
                     KGLEYATRICDKLGTVFKNRGAKLDKRLYILNSSKPTAVLIESFFCDNKEDYDKAKKL
                     GHEGIAKLIVEGVLNKNINNEGVKQMYKHTIVYDGEVDKILANVLSWGYSPSKVLVCD
                     IKDYVPGQTENLYVVGGGACEKISSITKEKFIMIKGNDRFDTLYKALDFINR"
     gene            complement(4794..5225)
                     /locus_tag="KRH23_003582"
     CDS             complement(4794..5225)
                     /locus_tag="KRH23_003582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HHS5226852.1"
                     /translation="MNVTIVFLATNIFIKLVILAIAFDTLLGCLRAIKTHQFNSSFGI
                     NGGIRKVAMIACIFFLAVVDILTKFNFLFMLPQDWVDFLRLNHLGISEFFSILFILYE
                     SVSILKNMYLCGLPVPKRLKEKIGSLLDTMTDELNVKGGSK"
     gene            complement(5287..5424)
                     /locus_tag="KRH23_003583"
     CDS             complement(5287..5424)
                     /locus_tag="KRH23_003583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HHS5226853.1"
                     /translation="MNWYKIITDFYNNGNWTKEQVKTAVTKNKITASEYKEIVREDYI
                     A"
     gene            complement(5426..5725)
                     /locus_tag="KRH23_003584"
     CDS             complement(5426..5725)
                     /locus_tag="KRH23_003584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226854.1"
                     /translation="MIYLGNLLDTEEQNIKYVGMIHYEPNLLSEENLKQGILVEELPT
                     PKYTENKETKLFINIDTKEVFYRYTDIKSSIEDKVNSTEQTIADLTFQLMSNGVI"
     gene            complement(5722..6957)
                     /locus_tag="KRH23_003585"
     CDS             complement(5722..6957)
                     /locus_tag="KRH23_003585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226855.1"
                     /translation="MTFKELVNKVRNLVLEAKNVTIEDTENNFTSDNVEGALKEVFQN
                     GVNAKSNVVTALNSKGADVTTSDTWEEIKNKIDIKEGRLDLRETILANSYSSYLVTNG
                     AIKYIEKYSGSLKALEYEEPYFYAIKGTHLIKINAIDESVIFDITLANANFSCICVTQ
                     EYLFISDNTKLYKINKLTGNEAQSIEGSYYKLCTYGEFIYGIYGDETSSILHKIRISD
                     MYIMLTKDMSSDRIYDFERGKFVCNNNGIYATTEHSNSSGLTECYLTKINFDFSVAKS
                     FRIGGYLYEKNIKFLNDFVFVSDSSRSIEVESGKKSGLAKYDANLNLITYGGSDRYEN
                     FEIYNGYIYTFNSLSSSPFIKINLNTLKEVNSYRTLINTNPQKGMFIINNIIFFIGGG
                     IHRNILSKKVYSDEKGEEL"
     gene            complement(6990..7172)
                     /locus_tag="KRH23_003586"
     CDS             complement(6990..7172)
                     /locus_tag="KRH23_003586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226856.1"
                     /translation="MNINNVVVRILAERILNGGLNPLKNREFELDDVTNAEYRKAVED
                     YIIRESGVVEEAEPTI"
     gene            complement(7172..7465)
                     /locus_tag="KRH23_003587"
     CDS             complement(7172..7465)
                     /locus_tag="KRH23_003587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226857.1"
                     /translation="MNRANRIIYDQTGKILLQTGEATGDILQHDTITELHCIDVEYGS
                     IDYTRNRIIGINIETKEPILEEIPVFISEEEKRIQELENQILLNENKKVGGIL"
     gene            complement(7479..9161)
                     /locus_tag="KRH23_003588"
     CDS             complement(7479..9161)
                     /locus_tag="KRH23_003588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine rich domain-containing protein"
                     /protein_id="HHS5226858.1"
                     /translation="MAKVYDFNYIHGEQEVVLPPGKYLLECWGAAGGGGIRIVDFNLR
                     SKGGYSKGELTLRKETTLYVYAGSKGSNYDSTFNGGGKAMMHESPSGGGILYCNGGGA
                     TDIRLIGGSWDNEQSLLSRIIVAGGGGRNNFETKGGDGGGDAGGDGSKADSKGTQTNG
                     GKGEAGLDGSFGKGGSAVSASSGENYGGGGGGWYGGGSGYNAGGGSGYVLTENSYKPA
                     GYIPTKEYWLENTSMTVGGGIAEENGKAKITLLQGLPFLVISSYTPEQAVFTAGHTEE
                     NKLSKIEWFIDDVLKETFTTDLYLEKTINYTLEDNALHTLKIVVTDINNMTYEQVVTI
                     SKSIMPLPADANLQDISTKLTEIGEGFKNGKTSIINTLALKNIEASLNNTLVELSEKI
                     KASFDSGDASAQDLMNQLTQANNTISQLNSKYKYASGTIDVVKNSSLMANLYGESFGR
                     QPGTWLKIDNLGFIPNIFVAECQYVTSNNYFFKHIVIATCNINWFWEKKDFSARIVFT
                     KEKNSNQDFSGSGIIYSNNERDVYINNKGINVPASSPNVSSYLHSWHAIKFI"
     gene            complement(9175..>9620)
                     /locus_tag="KRH23_003589"
     CDS             complement(9175..>9620)
                     /locus_tag="KRH23_003589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HHS5226859.1"
                     /translation="NEKQNIKIDQLIAGGSNVASTQIITIDDWVEDAENGFKATVTHS
                     LLTQRIVVNIIDATTKENVVTNFKIIDDNSIEIRSEVKAELNVYVINGNAETHFINAT
                     VDDNRVSEMTTYSSKKIEDRLINLEEKVNGGLSSITTNVNNMLPI"
BASE COUNT         3311 a         1576 c         1046 g         3687 t
ORIGIN      
        1 aaatgaaaaa gcactctcca taatgaagaa tgctctatat aataatgttt gacttagtaa
       61 agatgtgttg gggttacata tttacttttt tattatatca tataactttg tgtatgaaaa
      121 agaatttaaa tcaattttaa ggtgtgttga gtaatgttct tgatagttta tatgttgatg
      181 aatttcaaaa aaataagcac tcttataaaa agagtacttt tggtatatat tcaagcattt
      241 atctaataca attatagcat gtattatgtt ttagtatgat aattttcgtt cgttttatta
      301 ttacaacttc tactatagtt ttcatacttt aacatcaact aaatgaattt aattaagatt
      361 actagttaat cgttttttgg ttctttcata ttctgaaatc taaaatttta ttatttgttt
      421 attgttatta tttaacacat gttggtattt caacgattta tcttattgtt aatattctta
      481 ttgcttccaa agtatatcta attattttta agataattta ctaattttta ttttttcaaa
      541 catacattcg acaaaaaaca gtttttatat ggtataatta tattgtataa tacaaaaggt
      601 taatgaaaat aattaatatt aaatgtacca aaaaaaatag tttttgatat aatgaatatt
      661 ataataaata attatttaaa taaaatatta tataaggatg tgattttatg gatttcaaaa
      721 tcagagagct aattaatgat ataacccaag atattatcca aacatacaaa atccaaattc
      781 caatagtaaa tataaatcaa gttgttgatg ctttaggagg caaggtaata gaagatagtt
      841 ctttaagtgg atactctgat ggatttatta gaaaagttga tgattcattt gaaatagtgg
      901 tatctcctta tcaaccagat accagaaaga attttaccat tgctcatgaa cttggacatt
      961 tatttttaca catgggttat ggcattgatg atgaactatg gaatagtcaa gatggaaatc
     1021 agtattttag aagtggcaat accaataagg agtatcaatc caatgaattt gcagcagcct
     1081 tgttgatgcc taaacatgaa tataaaagaa ttatggatga aaacacagta ggtaataagg
     1141 tcgacacttc aaaaattgca gaatacttta atgtttcctc ttatgcagca tctaatagag
     1201 ggaaatggtt aggatattta caatggtaga tgataaagaa tataaaactc aaaatgtaaa
     1261 taatgttcat aattcagcta aaaacgaaaa cgcttttaat cttaaaaagt ataaggaaaa
     1321 acttcaagaa aatattaata ctgatattta tgaaaaagaa aaagaaccta atcatccaga
     1381 agtgattttg ttcttttctt ttgatatagc taattcatca ttatataaaa atataaatta
     1441 tagcggatgg gctaaggtat tatcacatat aattcgtaag ttacaatata gagtttatga
     1501 aaaccttaaa gcacaacttt ggagagttct tggtgatgag gtaattttca ttatcgtact
     1561 aaaaaattat gatgaaattt ataaatacat agatataatc tttgatattt taacaagcac
     1621 tgctaaagat ataaaaagtg gtaatatatt ctctacacta gaaggatttt ctgaatctga
     1681 aaaatactta atgaaacttc aaaatattat ttcattaaaa ggagcggcct ggattgctat
     1741 agtatcaaga aatcctaatt ttaatgcttt agaaaataat gaacaatatg aaaatatttc
     1801 tgctatgtac gatttatcca ataattataa aatatttgag ttcttaggaa atgatattga
     1861 tgctggtttc agaatatcaa agcaaacatg cccagaaaga cttgttctta gttttgaact
     1921 agcttatata ttatcaagaa aaactgatat tttatctaaa ttacatataa ttacatataa
     1981 aaaattaaag ggtatctgga aagataaact ataccctatc atttggtatc ataataaagg
     2041 aaaaaataat gatatagaat ttgatgatag tttttctttt gatgaaatag aagaaaatga
     2101 attggttcga gaatattttt ttaataaaaa aggagaaagt aaattactaa ttgattcttt
     2161 tatgtttaat tctgtagaca aggctttgga taaaatactt atagacagaa accttagtga
     2221 taagattgaa aaaataggtg acgtaatttc taaaacaaac cccagttatg ataaaaatac
     2281 aatagataaa gactatataa aagtagattt aatggaatta cactgtgttg cggtttgtta
     2341 taataaatca acttcaaaaa tattaattgc gaaaagaagt gataatagaa ataataatgc
     2401 gagtaaatgg gaatttggtt gtgctaaggc aagtctagaa acttcaatta taaatactat
     2461 taaagatgaa tatgaaaaag attttaatat aaacattgaa cctattactg attgcacaag
     2521 aaaagatgat tgccaaccta tacctctagc aatttatcaa gttaaaaaaa gtgatggttt
     2581 acacaaaggc attataactc tcgcagaaat aataaatgat tatgatattt ctaaatttga
     2641 acccacatca aaacataatg aacttgcatg gataggagag gatgaacttg aagattttaa
     2701 tgaaaacaca gtacctgatt ttaaagaaac tttaaaacta gcatttaaaa aattaaatga
     2761 aaatcaatta caagaatcta caaatatgta aatagtattc ttctatgatt tgattctatc
     2821 ttcatagagg aatactaacc aaataaaaca ttttctaaat agcattaaaa actactacaa
     2881 gtatatatat aaacaatata ataccaccta aaataaaagc ttctactgac ttttttacat
     2941 tatacatttt cttatcacag attaaagata attcttttat ttgaacaagt gcatcattaa
     3001 tcaagttttc ttcgtcttta aatgcatttt caaatgcttc tttgtactgt tcattattta
     3061 aagatgctat ctctttataa taaaaaatag atttatattc attttctatt ttagaattcc
     3121 ttggctttaa aaccataatc gaaaaataaa ttgaaataac aaatatacat aatataacaa
     3181 tgtaaaatag catctctaaa catctgatat tacttatact taagtgattc attatttttt
     3241 ccttccctga aaataaaaaa cctataattg cgctatttaa taatagtaaa aaactagctt
     3301 tattatctga tttttcaata tagtaatcaa ttctatttac tataaacttc gctatgtcta
     3361 tttttttatc catgatttta ctacctcatt tcattaaatt ttatattgat tcaaaatttt
     3421 attttctact tattatcatt gaataaatta ttatttggaa ataatcttat tgaaataata
     3481 aaaatatgtg aaagaaagta ataactaact ataattacta cttcctaact taaacattct
     3541 atctcttcca attaaaagta agatatcgtc ctctataagt ttcatattct cttataatat
     3601 ccaatatttc ctccctagaa gttgcaatta aacttctatc aaatagttca atcattctat
     3661 tgctatcatt atcagaaaca ttacaagact ctaatatctc attattaaat attgcaatag
     3721 catacccagt acctattttt atctcattta attcatgtaa attatttgct gctctaaaga
     3781 tatcagcttc agccaatcca cctaaatctt cgcttctatt aatcaagtta ttaagtttaa
     3841 tactaaaagc tgctcttaca aatctctcat aaaccaatgc atccatacat aaatcctcca
     3901 ttatcacaat aatatattta cattatatta caataataga gttatcacaa caaacaacca
     3961 cttctagttg ataactttta tctatctatt aataaaatcc aatgctttat aaagtgtatc
     4021 aaatctatca ttacctttta tcataataaa tttttcttta gtaatagaac ttatcttttc
     4081 acatgcgcca cctcctacaa catataaatt ttccgtctga cctggtacgt aatcttttat
     4141 atcacaaact aaaactttgc ttggactata gccccaacta agcacattcg caagtatctt
     4201 atcaacttct ccatcataaa caattgtatg tttgtacatc tgtttaactc cctcattatt
     4261 tatattttta tttaatacac cttctacaat taacttagca ataccttcat gacctagttt
     4321 cttagcttta tcataatctt ctttattatc acagaagaaa ctttcaatta atactgctgt
     4381 aggctttgaa ctatttaaga tatataatct tttatctaat ttagcacctc tatttttaaa
     4441 tactgtacct agtttatcac atattctagt tgcatactct aagcctttat tactataata
     4501 taggacttct gaacctttac cttgaccgtt acttgcattt aaatgtaact ctataagtaa
     4561 atcatatcct ccactattaa ctctaggtat tttataagac ttttcttcat tcttagtttt
     4621 aaactgcttt tctgggcata ttattacatc taccttatgc ccttcttttc taaatgtatc
     4681 tgctaatact ggtgcaagag atttgttgta ttgatactcg ttaactactc catcagcaga
     4741 agtacatgct ccacttttta aaatactgtg tcctactgtt atacatattt tcattattta
     4801 ctacctcctt taacatttaa ttcatctgtc atagtatcta ataaactacc tattttctct
     4861 tttaatcgtt taggaactgg taatccacat aagtacatat tttttaatat acttacactt
     4921 tcatatagaa taaataaaat agagaaaaat tcagatattc caagatgatt taatcgcaaa
     4981 aaatcaaccc aatcttgtgg caacataaat aaaaagttaa actttgtaag aatgtcaact
     5041 actgctagaa aaaatataca tgctatcatt gctacttttc ttattcctcc atttattcca
     5101 aaagagctat taaactgatg tgtttttatt gctcttaagc aacctaacag tgtatcaaat
     5161 gctattgcta atattactaa ttttataaat atatttgttg ctaaaaaaac tattgttacg
     5221 ttcatatttc ctccttattc tgcattaaaa taagacttag aaattatcta agtctattta
     5281 aaagaactac gctatatagt cctctcttac aatttcttta tattcacttg ctgttatctt
     5341 attctttgta accgctgttt taacttgctc tttagtccaa ttaccattat tatagaaatc
     5401 tgttattatc ttataccaat tcatactata tcaccccatt actcattaat tgaaatgtta
     5461 aatctgctat tgtttgttct gtagaattta ctttatcttc tatgctactt ttaatatctg
     5521 tatatctata gaaaacctct ttagtatcta tatttataaa taactttgtt tctttatttt
     5581 ctgtgtattt tggtgttggt aattcctcga ccaaaattcc ttgttttaag ttttcctccg
     5641 ataacaaatt tggttcatag tgtatcatac caacatattt tatattttgt tcctctgtgt
     5701 ctagtaaatt tcctaaataa atcataattc ctctcctttt tcatctgaat aaaccttttt
     5761 tgataatata tttctgtgaa tgccaccacc aataaaaaaa attatattgt ttattataaa
     5821 catacctttt tgaggatttg tgttaatgag cgttcggtag ctattaactt ctttaagagt
     5881 atttaaattt atttttataa atgggctact agaaagtgaa ttaaatgtat atatatatcc
     5941 attatatatt tcaaaatttt catatctatc tgacccacca taagtaatca aatttagatt
     6001 tgcatcatat tttgctaatc cacttttttt accactctca acttctatgc ttctgctact
     6061 atcagataca aaaacaaaat catttaaaaa cttaatgttt ttttcatata aatatcctcc
     6121 aattctaaaa cttttcgcaa cactaaaatc aaaatttatt ttagttaggt aacattctgt
     6181 aagaccactt gaatttgagt gttctgttgt agcataaata ccattattat tacatacaaa
     6241 tttgcctctt tcaaagtcat aaattctatc agaggacata tctttagtta gcattatata
     6301 catatccgat attcttattt tgtgaagtat tgaagaagtc tcatctccat atattccata
     6361 aataaattcc ccataagtac atagcttata ataagaacct tctattgact gtgcttcatt
     6421 tcctgttaac ttatttattt tatataattt agtattgtca gatataaata aatactcttg
     6481 agtaacacag atacatgaga agttagcatt ggctaaagta atatcaaaaa ttacagattc
     6541 atcaattgca ttaattttaa ttaaatgtgt acctttaatt gcataaaaat agggttcttc
     6601 atattctaat gcttttaaac tcccactata tttttcaata tattttatag caccatttgt
     6661 aaccaaatat gaagaataac tatttgcaag tattgtttct cttaaatcta atctcccctc
     6721 ttttatatca attttattct ttatttcttc ccatgtatcg cttgtagtaa catctgcacc
     6781 tttggagttt aatgctgtta ctacattact tttagcatta actccatttt gaaaaacctc
     6841 tttcaatgct ccttctacat tatcacttgt aaagttattt tctgtatctt ctatagttac
     6901 attctttgct tctaatacaa gatttctaac tttattaact aactctttaa aagtcattta
     6961 gtcaccttct ttcaataaaa aagaaccctc tatatagttg gttctgcttc ttcgactact
     7021 ccactttctc taattatata atcctctact gcttttctgt attctgcatt agttacatca
     7081 tccagttcaa attctcgatt ttttaaaggg tttaagcctc cgtttaatat tctctctgct
     7141 aatattctta ccacaacatt atttatattc attataaaat tcctcctact ttcttatttt
     7201 catttaataa aatttgattt tctaactctt gtattctttt ttcttcctcc gagataaata
     7261 ctggtatttc ttctaaaatt ggttcttttg tttctatatt tatacctata attctatttc
     7321 ttgtatagtc tatacttcca tactcaacat caatacaatg taattcagtt attgtatcat
     7381 gttgcaatat atctcctgtt gcttctcctg tttggagaag tattttgcct gtttggtcgt
     7441 aaattattct atttgctcta ttcattttat cacctctttt atataaattt tatagcatgc
     7501 caagaatgta ggtaactaga aacattagga ctacttgcag gaacattaat gcctttatta
     7561 tttatatata catcacgctc attatttgaa taaataattc cacttccact aaaatcttga
     7621 ttagaatttt tttctttagt aaatacaatt ctagccgaaa aatctttttt ttcccaaaac
     7681 caatttatat tacaagtagc aataacaata tgtttaaaaa aataattatt agaagtaaca
     7741 tattgacatt cagcaacaaa aatattagga ataaaaccta aattatcaat cttaagccaa
     7801 gtaccaggtt gtctaccaaa ggactctcca tataaattag ccattaaaga actattttta
     7861 acaacatcaa tagtaccact ggcatattta tacttagaat ttaactgtga tatagtatta
     7921 ttagcttgtg ttaactgatt catcaaatcc tgcgcactag cgtctccact atcaaaactt
     7981 gctttaattt tttctgataa ttccactaat gtattattta aacttgcttc tatattttta
     8041 agtgctaaag tatttataat acttgttttc ccatttttaa atccttctcc aatttctgtt
     8101 aacttagttg atatatcttg taaattagcg tcagctggta gtggcattat actcttactt
     8161 atagtaacaa cttgctcata agtcatgtta ttaatatctg taacaactat tttaagtgta
     8221 tgaagtgcat tatcttcaag tgtatagtta atagtttttt ctaagtataa atctgtagta
     8281 aaagtttctt ttaatacatc atctataaac cattcaattt tagatagttt attttcttct
     8341 gtatgtcctg ctgtaaaaac agcctgttct ggtgtataag aactaataac aagaaaaggt
     8401 aatccttgca ataatgttat tttagctttt ccattttctt ctgcaatgcc tccgccaaca
     8461 gtcatagaag tattttctag ccaatattct ttggttggta tatatccagc tggtttataa
     8521 ctattttctg ttaaaacata gccacttcca ccacctgcat tataaccgct cccacctcca
     8581 taccatccgc cacctccacc gccataattt tctcctgaac tagctgatac agcacttccg
     8641 ccttttccaa aagagccatc taatcctgct tcgcctttac caccattagt ttgagttcct
     8701 ttgctatctg ctttagaacc atcacctcca gcatctccac caccatctcc accttttgtt
     8761 tcaaaattat ttctaccacc tccacctgct acaattattc tagataaaag actttgttca
     8821 ttatcccaag aaccaccaat aagtcttata tctgttgctc cgccaccatt acaatacagt
     8881 attcctccac cagaagggct ttcatgcatc attgcttttc ctccaccatt aaatgtagag
     8941 tcataatttg aacctttcga accagcgtaa acatacaatg ttgtttcttt tcttaaagtt
     9001 aattctcctt tcgaatatcc tccttttgaa cgtaagttaa agtcaactat tctaatgcct
     9061 ccaccaccag ctgctcccca acattcaagt aaatactttc ctggtggcaa aacaacttct
     9121 tgttctccat gtatataatt aaagtcataa accttagcca tcttcttctc ctttctatat
     9181 aggtaacata ttattcacat ttgttgtaat actagataaa ccaccattta ccttttcttc
     9241 taaattaatc agcctatctt cgattttctt agatgaataa gtagtcattt cagatactct
     9301 gttatcatcc acagttgcat taataaaatg agtttctgca tttccattta tcacatagac
     9361 atttaactca gcttttactt cacttctaat ttctatagaa ttatcatcta taattttaaa
     9421 gtttgtaact acattttctt ttgtagtagc atctataata tttacaacta ttctctgtgt
     9481 taacaaacta tgtgttacag ttgctttgaa tccattttct gcatcctcaa cccaatcatc
     9541 aattgttatt atttgagtag atgccacatt tgaaccacct gcgattaatt ggtcaatttt
     9601 aatattttgt ttctcatttt
//
LOCUS       DAEORM030000098         9390 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.104, whole genome shotgun sequence.
ACCESSION   DAEORM030000098 DAEORM030000000
VERSION     DAEORM030000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9390)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9390)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 9390)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9390
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.104"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            complement(168..911)
                     /locus_tag="KRH23_003590"
     CDS             complement(168..911)
                     /locus_tag="KRH23_003590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HHS5226860.1"
                     /translation="MENYQSTNTCTYNILYVQFNEDFERSKYFSYDVKYPVIYNIRNQ
                     STYVNPVILNNINNAVRMTVNNFKNGLQEEEREYNNAASQNSLPKQSYWVSTSYAVTF
                     NKNYVLSMILNLMGFANNYGPKYNTLNNYNIDLTTGKELLLNDIFRDGVDYINIITDY
                     IKSQINENREMYYSNVELVIPEDQAFYITDNGIIIYFGVDEIAPESFGIPKFELKFSD
                     FGNFINLRFYCISPDIYVQSRGRAKHFMG"
     gene            1079..1951
                     /locus_tag="KRH23_003591"
     CDS             1079..1951
                     /locus_tag="KRH23_003591"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HHS5226861.1"
                     /translation="MLLLADKWKDYELIDMGNGEKLERWGSYVLRRPDPQVVWPMESE
                     WALWKNPHGHYHRSNKGGGQWEHKKRYPEQWTINYKNLKFHIKPTGFKHTGLFPEQAA
                     NWDWMIEKIKKANRPIKVLNLFAYTGGATVACASAGAEVCHVDAAKGMVNWAKENIEL
                     SGLKNQTVRFIVDDVVKFVEREIRRGKKYDAIIMDPPSYGRGPKGEVWQIEEKLYSFV
                     DLCMGVLSDNPLFFLINSYTTGFSPIVLENVLSTTIGKKTNTGDIYGGELGIPASRDG
                     KILPCGIFGRWEKK"
     gene            1951..2616
                     /locus_tag="KRH23_003592"
     CDS             1951..2616
                     /locus_tag="KRH23_003592"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HHS5226862.1"
                     /translation="MIKVIYEDNHLLVVEKPVNILSQGDNTNDKDMVNLLKDYIKKKY
                     NKPGNVYIGLIHRLDRPVGGVMVFAKTSKAASRLSEQVRSKTFKKTYLAVVHGKIKSN
                     SDILKDFLYKNKKTNMVTVVKKSHKDAKEAELNYNVLDFKENLSLVQVNLKTGRSHQI
                     RVQFASRKHPLYGDQRYGKEINKIGQQISLWSNKIEICHPTTKEKMEFTCHPPDKYPW
                     NIF"
     gene            2637..3494
                     /locus_tag="KRH23_003593"
     CDS             2637..3494
                     /locus_tag="KRH23_003593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HHS5226863.1"
                     /translation="MSKKFSIGEMSKLHKISIQTLRYYDQIDLFKPVHVDQESNYRYY
                     SIDQFSQLDIIKYLKYLGMPLKEIKSKLDENNEEILKLLTNKINIVDEKIKELELIKK
                     VLSTKKETMEKGMKVDEVGKIVRKHIPRRSILSIEYEEGLSSEETMELSRRQIANILE
                     DNISVFYGGVSGLVSIDKFLKEDKVIYDNSFVTVERDLFDIKSQKHITEISSGDFICM
                     TYKGPYKENYTAFKKLVDYVEYKRIPIENYIYEIPIIDPLSTNNEEELLTEIQIQVKK
                     REIDLRCLV"
     gene            complement(3650..5359)
                     /locus_tag="KRH23_003594"
     CDS             complement(3650..5359)
                     /locus_tag="KRH23_003594"
                     /inference="COORDINATES: protein motif:HMM:NF014717.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHS5226864.1"
                     /translation="MLGSIFLIYNSFNMSLNERTHQFGILSSVGATAKQLRNSVLFEG
                     ICIGAIGIPIGVAIGIVSIGLVISVIAKNFANILYVNVPLKLTLSIPAIIVAAVVSMV
                     TILISAYIPARKAANTPVMECIRQTNEVKIESKSVKTSKLTQRVYGLEGVLAMKNFKR
                     NKKRYRSIVLSLVLSIVLFISTSALVADLKQMSNQRSEVTDQDIIFSTQGMKDNEMLK
                     LYDKLKTANGVYEGLYQKLMTYSCVTKVSELTDDYLNYEGSHSMSEMLELPVDMQFLD
                     DRTYLNIIKSLGLPAEEYTGQNAKLIAVSMVTKDNNIIDIFNSSSMNVSLTPETNGKL
                     EIPERQNVNISFVKVVPPDSPPGIRSSDVKKASFRVLAPYSAKDKFEIPGVSTGIESL
                     SFQSKNPTQSVAEMEQIIESEGVTNEYNLYNMYGMMDENRNYIFIANVFAYTFIIMIS
                     LISIANVFNTISTNIKLRRRELAMLRSVGMSEHDFQKMMNFECAFYGMRALFFGLPIA
                     VISSWLIHKVMVTDDIDFVIPWFSIGISIFSVLFIVFITMLYTINKIKKENIIDALRD
                     DMA"
     gene            5364..5489
                     /locus_tag="KRH23_003595"
     CDS             5364..5489
                     /locus_tag="KRH23_003595"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226865.1"
                     /translation="MASTMPPTEYKNILNKLLSETPMKRNTLSLKMEAWSLVLLV"
     gene            complement(5648..6196)
                     /locus_tag="KRH23_003596"
                     /pseudo
     CDS             complement(5648..6196)
                     /locus_tag="KRH23_003596"
                     /inference="COORDINATES: protein motif:HMM:NF024116.6"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
     gene            complement(6196..6882)
                     /locus_tag="KRH23_003597"
     CDS             complement(6196..6882)
                     /locus_tag="KRH23_003597"
                     /EC_number="7.6.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHS5226866.1"
                     /translation="MAFLKIEDLCKVYGKNENKVTALDHVSLTIEKGEFTAIIGSSGS
                     GKSTLLHSIAGVDVPTSGKIYLEGQDVYGQSNEKLAIFRRRQVGLIYQFHNLIPTLNV
                     VENITLPILMDKRKVNQERLNDLLELLGLKERKTHLPNQLSGGQQQRVAIGRALMNAP
                     AVMLADEPTGSLDSKNGQEIIQLLKESHSKYHQTLIIVTHDENIALQADRIICISDGK
                     VVRDERKVNR"
     gene            complement(6965..7954)
                     /locus_tag="KRH23_003598"
     CDS             complement(6965..7954)
                     /locus_tag="KRH23_003598"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HHS5226867.1"
                     /translation="MFRNREFRKFAILFLLITILTVALGFAISIMTGILSIVSATTFG
                     IAFFVFTKNRYKSIAQISEQINLVLHNANHLYIAESDEGELSILQSEITKMTLRIREQ
                     NYALKKEKEHLADSLADIAHQLRTPLTSVTLILSLLENTSDEDERKELIRETEELLIR
                     MDWLITSLLKLSRLDAGIVVFQKEQIDVNNLISSALHQLLIPMELHNITLHIDIPKGV
                     RILGDLNWLSEAIQNIFKNCMESVGDNGKIDIICEDNFLFTQLTIHDNGAGFKKEDLP
                     CLFNRFYRGKNSSTAGYGIGLALCKTIIMRQGGTITAQNHPQGGAIFVIRFPK"
     gene            complement(7941..8627)
                     /locus_tag="KRH23_003599"
     CDS             complement(7941..8627)
                     /locus_tag="KRH23_003599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HHS5226868.1"
                     /translation="MKRIFLVEDDKAIAKNLILLLNSEGFIVTHVSTRSEALVEIAKN
                     KFDLALIDISLPDGNGFTICTEIKEKQDIPVIFLTASGDESSVVTGLNMGADDYITKP
                     FRPRELIARIRTALRKSGRFGSTFEICGLYVDTTTGVVKKNGNEVFLSALEYRLLLVF
                     ISNPKSIITRVRLLDELWDAAGEFVNDNTLTVYIKRLREKIEDDPSSPQIILTVRGTG
                     YRLGGSYVSK"
     gene            complement(8624..8746)
                     /locus_tag="KRH23_003600"
     CDS             complement(8624..8746)
                     /locus_tag="KRH23_003600"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226869.1"
                     /translation="MDYIRTKETTENCVMISKIVVYYCSAGIYKTNKIKEDESK"
     gene            complement(9127..>9390)
                     /locus_tag="KRH23_003601"
     CDS             complement(9127..>9390)
                     /locus_tag="KRH23_003601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226870.1"
                     /translation="GIEADIVNRIEEPRPNILDAIRNKQVDIVINTPTKGNDSTRDGF
                     KMRRTAIEFSTEIMTSLDTLKALVEVKKKHLNKDKLKVYNIAE"
BASE COUNT         3328 a         1579 c         1386 g         3097 t
ORIGIN      
        1 acttttaata caaaacaatc attctatttt aacatttatc aatatgtcta aatttatata
       61 attaacacat acgaatagta ttgtttaaat cacattattt aagatagata aatcttaacc
      121 ctactccagc ataaatacta aaatagggct tagaattatc tatattttta tcccataaaa
      181 tgcttagctc ttcctcttga ttgaacatat atatctgggg aaatacaata gaagcgtaaa
      241 tttataaaat ttccaaagtc agaaaacttc agttcaaact taggtatacc aaaactttca
      301 ggtgctattt cgtcaacgcc aaaatagatg ataattccat tatctgtaat ataaaatgct
      361 tggtcttcag gtataactaa ctcaacatta gaataataca tttctctatt ttcatttatt
      421 tgagatttaa tgtaatcagt aattatatta atataatcaa ctccatctct aaaaatgtca
      481 ttaagtaaaa gttcttttcc agttgtcaaa tctatattgt aattattcaa tgtattgtat
      541 ttaggcccat agttattagc aaaccccata aggtttaata tcatactcag tacataattt
      601 ttattaaaag taactgcgta actggtagat acccaatagc tttgttttgg aagtgaattt
      661 tgagaagctg cgttattata ttctcgttct tcttcctgta agccattttt aaaattattt
      721 acagtcattc ttacagcatt gtttatgtta tttaaaataa ctgggtttac atacgtggat
      781 tgatttctaa tattgtatat aacaggatac tttacatcat atgaaaaata cttacttctt
      841 tcaaaatctt cattaaattg tacatataat atattatatg tacaggtatt tgtagattga
      901 taattttcca ttaaaatcct ccccctttta taaaaaaatc agatacaata taatatgctt
      961 aaaacagtaa taatgttaat ggtaaatgta aagaatagaa agtatctaaa acagcaaaaa
     1021 atgactaatt ttgtggtata atacatagga ttgagagtta ttttatagga ggaaaaatat
     1081 gttattatta gcagataaat ggaaagatta tgaacttata gatatgggaa atggagaaaa
     1141 attagaacgt tggggaagtt atgtacttag aagaccagac ccacaggttg tatggccaat
     1201 ggaatctgaa tgggctttat ggaaaaaccc tcatggacat tatcacagaa gcaataaagg
     1261 tggaggtcaa tgggaacaca aaaaaagata tccagaacaa tggactataa attataaaaa
     1321 cttaaagttt cacattaaac caactggctt taaacatact ggattattcc cagagcaagc
     1381 agctaactgg gattggatga tagagaaaat aaagaaagct aacagaccta taaaagtgtt
     1441 gaatcttttt gcatatacag gtggagctac tgtagcatgt gcatctgctg gtgcagaagt
     1501 atgtcatgtt gatgctgcaa aaggtatggt taattgggca aaagaaaata tagaattatc
     1561 aggtcttaaa aatcaaacag taagatttat agtggatgat gttgtaaagt ttgttgaaag
     1621 agaaataaga agaggtaaaa aatatgatgc aataataatg gaccctcctt cttatggaag
     1681 aggtcctaaa ggagaagtat ggcaaataga agaaaagtta tacagctttg tagatttatg
     1741 tatgggagtt ttatcagata accctttatt tttcttaatt aattcttata caacaggatt
     1801 ttctccaata gttcttgaaa atgtattgtc tacaacaata ggtaaaaaga caaatacagg
     1861 agatatatac ggtggggaat taggaatacc agcttccaga gatggtaaga tacttccttg
     1921 tggtatattt ggaagatggg agaaaaaata atgataaaag tcatatatga agataaccat
     1981 ttattagttg tagaaaaacc agttaacata ttgtctcaag gagataatac taatgataaa
     2041 gatatggtaa atcttttaaa agactatatt aaaaaaaagt ataacaaacc tggaaatgta
     2101 tatattggtt taatacatag attggataga ccagtaggtg gagttatggt gtttgcaaaa
     2161 acatcaaaag cagcatctag attgtctgag caggtaagaa gtaagacttt caaaaaaact
     2221 tatctagctg ttgttcatgg caagataaaa tctaactcag atatactaaa agatttttta
     2281 tataaaaata aaaaaactaa tatggtaact gtagtgaaaa aaagccataa agatgccaaa
     2341 gaagctgaac ttaactataa tgtattagat tttaaagaaa atctaagttt agttcaagtt
     2401 aatttaaaga ctggtcgttc tcatcaaata agagttcaat ttgcaagcag aaaacatcca
     2461 ttatacggag accaaagata tggcaaagaa ataaataaga ttggacaaca aatatctctt
     2521 tggtccaata agatagaaat ttgccatcct actacaaaag aaaaaatgga atttacatgt
     2581 catccacctg acaaatatcc atggaatata ttttaaatct caaatgaggt gattatatga
     2641 gtaaaaaatt ttcaatagga gaaatgtcta aacttcataa aataagcata cagacactaa
     2701 ggtactatga ccaaatagat ttatttaaac ctgttcatgt tgaccaagaa agcaattaca
     2761 gatattactc aattgaccaa ttttcacaat tagatattat aaaatattta aaatatttag
     2821 gtatgccttt aaaagaaatt aagtcaaagc ttgatgaaaa taatgaagaa attctaaaat
     2881 tactaacaaa taaaattaat atagtggatg aaaaaattaa agaattagag cttataaaga
     2941 aggtactaag cacaaagaaa gaaactatgg aaaaaggtat gaaagtagat gaagttggta
     3001 aaatagtgag aaaacatatt ccacgaagaa gtatcttatc tatagagtat gaagaaggat
     3061 taagtagtga agaaactatg gaactttcca gaagacaaat agcaaatata ttagaagata
     3121 atatatctgt gttctatggt ggagtaagtg gacttgtatc tatagataaa tttttaaaag
     3181 aagataaagt tatttatgac aatagttttg ttactgttga aagagactta tttgatataa
     3241 aatcacaaaa acatataaca gaaatttcat ctggtgattt tatttgtatg acatataaag
     3301 ggccttacaa agaaaattat accgctttta agaaactggt tgattatgtt gaatataaaa
     3361 gaatacctat tgaaaattat atatatgaaa tacctataat agaccctctg tctacaaaca
     3421 acgaagagga acttctaaca gaaattcaaa tacaagttaa aaagagagaa attgacttaa
     3481 gatgtctagt gtagtaatct agtttactta cacatcttaa tatagttgtc tattatcaac
     3541 atatgatttt tctagatagt gattcctaac agtgagattt tcaaaaaata ggaggaaata
     3601 tggctaatgc taattccctc ctatttttaa ttaatccata tcattttaat taagccatgt
     3661 catcacgaag tgcatcaata atattttctt tttttatctt attaatagta tacaacattg
     3721 taataaatac tataaataaa acactaaata tactaattcc aatactaaac catggaatca
     3781 caaaatcaat atcatctgta accattactt tatgaattag ccatgaagaa attactgcta
     3841 taggaagtcc aaagaacaat gctctcatgc cataaaaggc acactcaaaa ttcatcatct
     3901 tttggaaatc atgctcagac attcctacag agcgaagcat ggcaagttct ctacgacgta
     3961 acttaatatt agttgaaatt gtattaaaca cattggcaat cgaaatcaga gaaatcataa
     4021 ttatgaaagt ataagcaaaa acattggcaa taaaaatgta attacggttc tcatccatca
     4081 ttccatacat attgtacaga ttgtactcat tcgtaactcc ctcactctca ataatttgct
     4141 ccatttctgc aactgactga gtaggatttt tcgattgaaa gcttaaactt tcaattcctg
     4201 tagaaacacc aggaatctca aacttatctt tggctgaata aggagccaat actctgaagc
     4261 ttgctttctt cacatctgaa cttctgattc ctggaggaga atcaggtggc actactttga
     4321 caaatgaaat attcacattt tgtctctcag gtatctccaa cttgccatta gtttcaggag
     4381 tgaggctaac attcatagaa gaactgttga aaatatcaat aatattatta tcctttgtta
     4441 ccatagaaac agcaatcagt tttgcatttt gtccagtata ttcttctgct ggtaatccaa
     4501 gacttttaat aatattcaga taagttctat catcaagaaa ttgcatatct actggtaatt
     4561 caagcatttc actcatagaa tgtgaaccct catagttcaa ataatcgtct gtaagctcac
     4621 ttactttggt aacacatgaa taggtcataa gtttctgata caaaccttcg taaacaccat
     4681 ttgcagtttt tagcttatcg taaagcttca acatttcgtt gtctttcata ccttgtgtag
     4741 aaaaaataat atcctggtca gtaacctctg acctctgatt tgacatctgt tttaggtctg
     4801 ctactaaagc acttgtagat ataaatagaa ctatgcttaa aacaagcgac aatacaatac
     4861 ttcgataacg tttcttgttt cttttaaagt ttttcatagc aagaactccc tcaagaccat
     4921 aaactcgctg tgttagtttt gatgtcttca cagatttaga ttcaattttt acctcatttg
     4981 tctgacgaat acactccatc actggtgtgt tggcagcctt tcttgctggt atgtaagcag
     5041 aaattaagat tgtaaccata cttaccactg ctgcaacgat gattgcaggg atagacaatg
     5101 ttaatttcaa cggaacgttt acatagagaa tatttgcaaa gtttttagct atgacagaaa
     5161 tcacaagtcc aatactgact ataccgattg caacaccaat tggtatacca atcgcaccaa
     5221 tgcaaattcc ttcaaatagc accgaatttc gtaactgttt tgctgtagct ccaacagatg
     5281 aaagtattcc aaattgatgt gttcgctcgt tcaatgacat gttaaatgaa ttatatatta
     5341 gaaaaattga gcctagcatg attatggcaa gcacaatgcc accaaccgag tacaaaaaca
     5401 tattgaacaa attgttatca gaaacaccta tgaagcgcaa cacattgtca ttgaaaatgg
     5461 aagcatggtc tttagtgcta cttgtgtaag agcgaatctg atgtggattt ttcaatgtga
     5521 caaaaaggct aagactgtca gtcttgactt gtttatcttc tttggttatc aaggtatatc
     5581 ctggtgcaga agattcttca aatacgggct ttctacagat acccacaact gtataagttt
     5641 tcttatcctg tggcacaaaa acttcactcc cagcagtgta tgggtcactc tgaccaagct
     5701 tttcattttc actcattcgt ttccctacat ccaaagaaat agtatcacct actgcaaatt
     5761 tgacaccacc atctgtcgca actttacttg aaacaagaat ctctctacta ttttcaggta
     5821 atcttccaga aattaaagtt ataggcaaag tatcaaaagc ttctttgcta aatccagcaa
     5881 taaaaagata tggtttatct ggatttctgt taccttcaag tgttgcatag ccaatatttt
     5941 caaatgttgc agtatttgca acttcatcat tgactctttg ttcctgtaca aaagaagaat
     6001 ccacatccaa aaactggaca tgccaatcac catattttat aatagctcca tttgtcatat
     6061 agttcatcaa agaaactcca aaggtagtaa ctgctgtaat catagcagct gacagaacaa
     6121 ctcctataat tgttacaaga gttcgagtgc gattcttttt caatccttgc agagcaactt
     6181 tgttaaaaat gttcattaac gattcacctt cctctcatca cgcactactt ttccatctga
     6241 aatacagata attctatctg cctgtaaagc aatattttca tcatgtgtga caataatgag
     6301 agtttggtga tatttactat ggctctcttt cagtaactgg ataatctctt gtccattttt
     6361 actgtctaag ctacctgtag gctcatcagc aagcataact gctggtgcat tcatcaatgc
     6421 acgaccaatg gcaacacgtt gctgttggcc accagaaagt tgatttggta aatgtgtttt
     6481 tcgttctttt aaaccaagta attctaacaa gtcatttaac cgttcttgat tgaccttacg
     6541 cttatccata agtataggca atgtgatatt ttccactaca tttaatgtgg gtatcagatt
     6601 gtgaaactga taaatcaatc caacttgtcg cctacgaaaa atagcaagtt tttcattact
     6661 ttggccatat acatcttgcc cctccagata tatctttcca cttgttggta cgtctactcc
     6721 tgcaatggaa tgtagtagtg tagatttacc agaaccagaa gaaccaatga ttgcagtaaa
     6781 ctcccctttt tcaatagtaa gtgagacatg gtcaagtgca gtaaccttat tttcattctt
     6841 accataaacc ttacataaat cttcaatctt taaaaacgcc attatataag tctcctttca
     6901 tattttataa atatatcata gaactttcaa cttacattta agtgacattt aaatgagaga
     6961 ttcgtcactt tggaaaacga ataacaaata ttgcaccacc ttgtgggtga ttttgtgcag
     7021 taattgttcc tccttgtctc ataataatcg tcttacaaag tgccaatcct attccataac
     7081 cagctgtgct tgaatttttc ccacgataaa atctgttaaa tagacatggt aagtcttctt
     7141 ttttaaagcc tgctccgttg tcatgaatag taagttgagt aaacaaaaag ttgtcctcac
     7201 aaatgatatc aatttttcca ttatcaccca cactctccat gcagttttta aatatatttt
     7261 gaattgcttc tgaaagccaa tttaaatcac ccaaaatcct tactcctttt ggtatatcaa
     7321 tatgtaaagt gatattgtgc agttccatgg gaatcaaaag ttgatgaagt gcagaactaa
     7381 tcaaattatt cacatcaatt tgttcttttt gaaagactac aatacctgca tctaaacgtg
     7441 ataattttaa aagggaagta atcagccagt ccattcgtat aagtaattcc tctgtttctc
     7501 gtatcaactc ttttctctca tcttcatcag aagtattctc taacagtgac aaaataagag
     7561 ttactgatgt aagaggagtg cgaagctggt gggctatgtc agctagtgag tcagcaaggt
     7621 gttctttttc ttttttcagt gcgtaatttt gctctctaat acgtaacgtc attttagtta
     7681 tttcactttg tagaatagaa agctcaccct catctgattc agcaatatac agatggttag
     7741 cattatgaag cacaagatta atttgttctg aaatctgtgc aatacttttg tatcgatttt
     7801 tagtaaacac aaaaaatgct attccaaagg tagtggcaga aacaatagaa agtattccag
     7861 tcataatact gattgcaaat cccagggcta cagtgagaat agtaattaat aagaataaaa
     7921 tagcaaattt tcgaaactct ctatttcgaa acataacttc cccccaatct ataccctgtc
     7981 ccacgaacag tcaaaattat ttgtggactt gaagggtcat cttctatctt ctctcgcaag
     8041 cgtttgatgt acacagtcaa tgtgttgtca ttaacaaact cacctgccgc atcccacaat
     8101 tcatcaagta atcttaccct cgtaataata cttttaggat tgctaataaa caccaataac
     8161 aaacggtatt ctaaagctga aagaaaaacc tcattgccat tctttttcac aacaccggtt
     8221 gttgtatcta cataaagccc acaaatttca aaagttgacc caaaacgccc actttttcgt
     8281 agtgctgttc taattcgcgc aatcagttca cgtggacgaa aaggtttagt aatataatca
     8341 tctgcaccca tattcagtcc agtaacaaca cttgattcat caccggaagc tgtcaaaaag
     8401 ataacaggaa tgtcttgctt ttctttgatt tctgtgcaaa tcgtaaaccc atttccatca
     8461 ggtaaagaaa tatcaataag tgccaaatca aatttattct tagcaatctc tacaagtgct
     8521 tcacttcttg tggatacatg ggttactata aatccttctg aattaagcaa aagaataaga
     8581 tttttggcaa ttgctttatc atcctcaact aaaaatatcc gtttcattta ctttcatcct
     8641 cctttatttt attagtttta tatattccag cagagcaata gtacactact attttactta
     8701 tcattacaca attttcagta gtttcttttg ttcttatata atccatgcat aatacctcca
     8761 ttgatttatt atatttctta taacataaat acacaagata agacaaaaaa cataatgtaa
     8821 gtgcaagttt tttaactcac taacttataa acatacactc ctactaacac tactttcttg
     8881 atgacacatc ttacaagctt atattcatac atcaatgaaa aattaaattt atccatttat
     8941 taaaataaaa ggcaatagct tctatagcta atgcccttta tcttaaaatg atttaaatac
     9001 tatacaattt ttataaatgg ctataaataa actcgtatag aatataaaat ttatctacag
     9061 tcttttgtta tacaaaattt ataacctctt atagaacaaa tttaccactt tgcaaactta
     9121 tcacttttac tcagctatat tataaacttt taatttatct ttgtttaaat gtttcttctt
     9181 aacttctact aaagctttta gcgtatccaa agatgtcatt atttcagtag aaaattcaat
     9241 ggctgttctt ctcatcttaa atccatctct tgtagagtca tttcctttag ttggtgtatt
     9301 tattactata tcaacttgtt tatttcttat agcatctaat atgtttggtc taggctcttc
     9361 aattctattt actatatcag cctctattcc
//
LOCUS       DAEORM030000099         8920 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.105, whole genome shotgun sequence.
ACCESSION   DAEORM030000099 DAEORM030000000
VERSION     DAEORM030000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8920)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8920)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 8920)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8920
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.105"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            125..634
                     /locus_tag="KRH23_003602"
     CDS             125..634
                     /locus_tag="KRH23_003602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HHS5226871.1"
                     /translation="MNSNERRSKLIDILKESKHPVKGGTLAELLNVSRQVIVQDIALI
                     RARGFEIIATPQGYIIYNQPYFTKQIKCKNHKDSKEIYDELKIIVDLGGIIKDVIVNH
                     PTYGQITAELNIYSKMDIDNFMKKVETNEFKQLSVLTECSHIHTIEAIKEETIKAIVK
                     ELKDNGILS"
     gene            646..1527
                     /locus_tag="KRH23_003603"
     CDS             646..1527
                     /locus_tag="KRH23_003603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008381 - mechanosensitive monoatomic ion
                     channel activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HHS5226872.1"
                     /translation="MNFLSLAKTASTNSNITKRTLENMLDNFSDNIPNIIYAIIVFVI
                     GIYISKIVRRMVSKFLIKYGMSKGVNNFIVYGIYISMLSIISLISLGIIGIQTTSVVA
                     VLGAAGFSIGLAFKEILSNLGSGMIILFFKPFNIGDYIQGSGVEGTVSDIQIFSTVLK
                     TPDNKTIIIPNFQLTSNNIINYTHQNKRRIDFSYNISYDSDIDVVKSILNEIFTNEKR
                     ILNDPKPIIGLNSIGNNTMQIVARPWVKTDDYWDVYFDVMEKVKNKFDENDIKVPFVP
                     SSLLFNNTGNLNTMDKR"
     misc_binding    1655..1860
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            1986..3257
                     /gene="serS"
                     /locus_tag="KRH23_003604"
     CDS             1986..3257
                     /gene="serS"
                     /locus_tag="KRH23_003604"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006441208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004828 - serine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006434 - seryl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HHS5226873.1"
                     /translation="MLDIKRIRENLDDIKKAMERRGEREFDLDAVVELDNKRREILQE
                     VEVMKNELNVNSKKIPQLIKEGKDVTEEKARLKELSDKIKGIDEKVKEVEAKMEYTLM
                     RIPNVPHPEVPQGETDEDNVQIRTWGEPTKFDFEHKAHWDIGTGLGILDFERAGKITG
                     SRFTLYRGLGARLERSLMNFFLNTHTAKHGYTEVLPPFMANRNSFIGTGQLPKFEEDM
                     FKIEGLEYFLIPTAEVPVTNIHANEILDVAELPIKYCAYTPCFRSEAGSAGRDTRGLV
                     RQHQFNKVELVKFVKPEDSYNELESLTHDAETMLQMLGLPYRVVKICTGDLGFTAAFK
                     YDLEVWMPSYNRYVEISSCSNFEDFQARRAGIRFKRDKKSKAEYVHTLNGSGLAIGRC
                     LAAILENYQQADGSVVVPEELRPYMGVDVIK"
     gene            3578..4033
                     /locus_tag="KRH23_003605"
     CDS             3578..4033
                     /locus_tag="KRH23_003605"
                     /EC_number="3.5.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0019239 - deaminase activity [Evidence
                     IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HHS5226874.1"
                     /translation="MESSFYMKEALKEAYKAYNKKETPIGAIIVKDNQIIARAHNLTE
                     TLKDSTAHAEILAIKQASEKLGGWRLTDCDLYVTMEPCIMCSGAIVNSRIKKLIIGTR
                     HVKNSYIEKQHEFKLDYFNNNNVKVAFDVLQEECSIILQEFFKALRKRD"
     gene            4034..4125
                     /locus_tag="KRH23_003606"
     tRNA            4034..4125
                     /locus_tag="KRH23_003606"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4068..4070,aa:Ser,seq:gga)
     gene            4163..4427
                     /gene="ffs"
                     /locus_tag="KRH23_003607"
     ncRNA           4163..4427
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="KRH23_003607"
                     /product="signal recognition particle sRNA large type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF01854"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF01854"
     gene            4504..6141
                     /gene="dnaX"
                     /locus_tag="KRH23_003608"
     CDS             4504..6141
                     /gene="dnaX"
                     /locus_tag="KRH23_003608"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HHS5226875.1"
                     /translation="MHKALYRAYRPQKFEDVIGQDHIIKTLKNQIYSDNIGHAYLFCG
                     TRGTGKTSTAKIFSRAVNCLNKINEEPCNECEICESVLKDNTMDVVEIDAASNNSVDD
                     IRELRESVKYSPANAKYKVYIIDEVHMLSQGAFNALLKTLEEPPSYVIFILATTEPHK
                     IPATILSRCQRYDFKRVTVKDMTLRMKKICEDEGIDIDDKALNLIARNSQGALRDALS
                     ILDQCMSFGESKIDYKDVVELMGSVNIEQLFELSQCIVEQDTKKSLEILNEFVLWGKD
                     IRNLINDLIDHFRNLMVCKVSSELDEIISLPEETIEQLKIQSKNIDINDLIRILNILS
                     ITQDDIKSSSNPRVLVEITIMKIAQPMFDESKEALIKRVENLEKMIELGNFKSEKIGN
                     NKEKEYEVDREIDVKQENVVYEDVKNEDVILIESSWKNILKQIKKDKKMPIYALLSEV
                     KSFNVYSNMLYVIFDDKFDFAKTRLSSQDTINYLEKTIRDVLNRSFNVKIVLTSEVKD
                     INLEVKEKKDIGEEILKNIVSEEILEIKDSIDENESK"
     gene            6200..6550
                     /locus_tag="KRH23_003609"
     CDS             6200..6550
                     /locus_tag="KRH23_003609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HHS5226876.1"
                     /translation="MAKKGFGGGMMPGGGNMNNLLKQAQKMQENMQKAQQELESKEVE
                     ASVGGGAVTVKVNGKKEVIDITIKPEVVDPDDIEMLQDLVLSAVNQALRNIDDIQASQ
                     MSKVTGGMNIPGLF"
     gene            6563..7162
                     /gene="recR"
                     /locus_tag="KRH23_003610"
     CDS             6563..7162
                     /gene="recR"
                     /locus_tag="KRH23_003610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombination mediator RecR"
                     /protein_id="HHS5226877.1"
                     /translation="MQVYTGPITRLIEEFSKLPGVGRKTAQRLAFHIINMNTNDVEAL
                     SKAIIDAKREIRYCSICCNITDTDPCSMCSNKSRDSSVICVVEDPRDVAAMERTREFK
                     GQYHVLNGVISPMDGIGPDMLKIKELIQRLGNQEVKEIIMATNPTIEGEATAMYIARL
                     VKPMGIKVTRIAHGLPVGGDLEYADEVTISKALEGRREI"
     gene            7303..7524
                     /locus_tag="KRH23_003611"
     CDS             7303..7524
                     /locus_tag="KRH23_003611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226878.1"
                     /translation="MKPIMNLEEHNAMKEKRVKKMKSKDKPKYDDFEDISFSNKKKTK
                     KNVRNKNAEFRNNYKNYQYDYEEDFYEPI"
     gene            complement(7595..8800)
                     /locus_tag="KRH23_003612"
     CDS             complement(7595..8800)
                     /locus_tag="KRH23_003612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016758 - hexosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009247 - glycolipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MGDG synthase family glycosyltransferase"
                     /protein_id="HHS5226879.1"
                     /translation="MSKKVLIMSASTGGGHNRAALAIKEELTSKTLDGEPIECEIIDS
                     LKLVNNTMDKIISRGYEKSAIYTPKAYGSVYRLSETNLLSKNEFKDNLLITFMAKKFK
                     KLIRSEKPDLIIGTHPFPMIALSTLKKNFNLHNNESNAYTEHFYKHYTNTINVPPLIS
                     VLTDYTTHSTWIQNEIDYYIVGHEYVKELLVFDGVEPSKIRTFGIPVEKSFLSHRDKD
                     IVLSELNLSPDKLTVLLMGGSFGAGNIKETLDELLDTDRDFQILVITGKNESLKEKIE
                     KKLMSRYHDKNVCVLGYTDKMNDILASIDVLVSKPGGLTTTEALLKDVPMIVPYYIPG
                     QEEENLDFLSNCGAALRTTKKYNLSILLKVLIDDPSRLEMLKRNIKSIRKSNSAQNIA
                     NLILNIISG"
BASE COUNT         3530 a          962 c         1572 g         2856 t
ORIGIN      
        1 tcttttttta tttattataa aagttaagat taaatagaat ataaagtcaa tattgattta
       61 taataagata aaatataaaa ttatatagta taggtaaagt ttttatttgg aaagaaggtg
      121 taatatgaat tctaatgaaa gaagaagtaa attaatagat attttaaaag aatctaagca
      181 tcctgtaaaa ggtggaacac tagctgaact attaaatgta agtaggcaag taatagttca
      241 agatatagcc cttataagag ctagaggatt tgaaataata gctacacctc aaggatatat
      301 aatatataat caaccgtatt ttacaaaaca aataaagtgt aaaaatcata aggattctaa
      361 agaaatttat gatgaattaa agataattgt ggatttaggt ggtattataa aagatgtcat
      421 cgtaaatcat ccaacatatg gtcagataac tgcagaactt aatatttatt ctaaaatgga
      481 tatagacaac tttatgaaga aagttgagac aaatgaattt aaacaattat cggttctgac
      541 agaatgtagc catattcata caattgaggc aataaaagaa gaaactataa aagctatagt
      601 aaaagagtta aaggacaacg gaatattatc ataaggagga gttgaatgaa ttttttatca
      661 ttggctaaga ctgcctcaac aaatagcaat ataactaaga gaactttaga aaatatgctc
      721 gataatttta gtgataatat accaaatatt atatatgcaa taattgtatt tgtgataggt
      781 atttatatat ctaaaatagt aagaaggatg gtttcaaagt ttctaatcaa atatggaatg
      841 agtaaaggtg taaataattt cattgtatat ggaatatata tatctatgtt atctattata
      901 tcattgataa gcttaggtat tatagggata caaactacat cagttgtagc tgtgttagga
      961 gctgctggat ttagtatagg tttagctttt aaagaaatat tatcaaattt aggctctggt
     1021 atgattattt tattttttaa gccatttaat ataggtgatt atattcaagg ttcaggtgta
     1081 gaaggtacag tttctgacat acaaatattt agcactgttc ttaagacgcc agataataaa
     1141 actataatta tacctaattt tcaactgaca agtaataata taattaatta cacacatcaa
     1201 aacaaaagaa gaatagattt ttcatataat atttcatatg atagtgatat agatgtagtt
     1261 aagtctatat taaatgaaat ttttacaaac gaaaaaagaa tattaaatga tccaaagcct
     1321 ataataggtt taaactctat aggaaataac accatgcaaa tagttgctag accttgggta
     1381 aaaactgatg attactggga tgtatatttt gatgtaatgg aaaaggtaaa aaataaattt
     1441 gatgagaatg atataaaagt tccatttgtt ccttcttcat tattatttaa taatacaggt
     1501 aatctaaata caatggataa aagataaggt cttaattaaa tagaaaaaat gaatttaata
     1561 taaaaaatta aagaaaattc taaaaaaatt tgaataatag tattgaaaga tgttaatata
     1621 tataatataa tgattatcaa ataaaacaat tagttaaaaa gctgtgaagg aaaatagtaa
     1681 aaaacagatt gtattcagag aatgagtgga tggtgaaaac tcattacaat ggtttttgaa
     1741 tctactctag agcttctagt taaagctaga cgtttaccta cgttataggt ctgagaggat
     1801 tatacatttt agtatagtca attagggtgg caacgcggat aaaagatttt cgtccctttt
     1861 atagggtaaa cggaggtctt tttttatttt taaaatttgt ttaaactaag agtttacaag
     1921 tataatgttt gtaaattaag ttggaattat aacttatatt atcaaaatta ttaggaggaa
     1981 ttaatatgtt agatattaaa agaataagag aaaatctaga tgatatcaaa aaagctatgg
     2041 aaagaagagg tgaaagagaa tttgaccttg atgctgtggt ggaattagat aataaaagaa
     2101 gagaaatact tcaagaagtt gaagttatga aaaatgagtt aaatgtaaat tctaaaaaaa
     2161 tacctcaatt aataaaagaa ggaaaagatg taacagaaga aaaggcaaga ttgaaagagt
     2221 tatcagataa gataaaaggt attgatgaga aagtaaaaga agtagaagca aaaatggaat
     2281 atacattaat gagaatacca aatgttcctc atccagaggt accacaaggt gaaacagatg
     2341 aagacaatgt tcaaataaga acttggggag aacctactaa atttgatttt gagcataaag
     2401 cgcattggga tataggtaca ggtctaggta ttttagattt tgaaagagca gggaaaataa
     2461 ctgggtcaag gtttacttta tataggggat taggagctag attagaaaga tctttaatga
     2521 atttcttttt aaatactcat acagctaagc atggctatac ggaagtctta cctccattta
     2581 tggccaatag aaatagtttt atagggactg gtcaacttcc taaatttgaa gaagatatgt
     2641 ttaaaataga aggattagag tatttcttaa taccaacagc tgaagttcct gttactaata
     2701 tacatgctaa tgaaatatta gatgttgcag agcttccaat taaatactgt gcatatactc
     2761 cttgttttag atctgaagca ggttcagcag gaagagatac aagaggttta gttagacaac
     2821 atcaatttaa taaagttgaa ttagttaaat ttgttaaacc agaagattct tataatgaat
     2881 tagaatcatt aactcatgat gctgaaacta tgttacaaat gttaggtctt ccatatagag
     2941 ttgtaaaaat atgtacagga gatttgggat ttacagctgc atttaaatat gatttagaag
     3001 tttggatgcc aagctacaat agatatgtag aaatatcttc ttgttcaaat tttgaagatt
     3061 tccaagcaag aagagcagga ataagattta aaagggataa aaaatcaaaa gcagaatatg
     3121 ttcatacatt aaatggttct ggattagcga taggaagatg tttggctgct atattagaaa
     3181 attatcagca ggcagatggt tctgtagtag ttccagaaga attaagacct tatatgggtg
     3241 ttgatgttat aaaataaatt tatattaatt gtatatgtag agtatgcttt gatgaagaga
     3301 atatattatg agtaaacaat aaataaaaaa actatgaaat tattataaat attaatttca
     3361 tagttttttt atgttaattt acacagcaga attttcatca taaaacacta aatattttta
     3421 taaaacactc ttgtatgaat atctaaaaat tattttagaa ctaattaaaa aaaaatatag
     3481 ctatatatag taataattaa ataaacaaaa taaaattaag ttgaattata aaatgaatta
     3541 tgataagata agtttgttat aagttttggg aggaattatg gaaagttcat tttatatgaa
     3601 agaagcatta aaagaagcat ataaagcata taataaaaaa gaaacaccaa taggtgctat
     3661 tatagttaaa gataatcaaa taatagctag agctcataac cttacagaaa cgttaaaaga
     3721 ctctacggca catgcagaaa ttttagcgat aaaacaagca tcagaaaaat taggtggttg
     3781 gaggttgact gattgtgatt tatatgttac aatggaacct tgcataatgt gtagtggtgc
     3841 aatagttaat tctagaataa aaaagcttat aatagggaca agacatgtaa aaaattcata
     3901 tatagaaaaa cagcatgagt ttaaattaga ttattttaat aataataatg taaaagtagc
     3961 ttttgatgtt ttgcaagaag aatgctcgat catattgcaa gaatttttta aggcattgag
     4021 aaaaagagat taaggagaga tggtcgagtg gtcgaaggcg ctcgcctgga aagcgagtat
     4081 atgggtaaaa ctgtatcgtg ggttcaaatc ccactctctc cgccagaaac aatgaaagta
     4141 attaaatatg gttgtaattt tgctgtacta gatggggagg tagcggtgcc ctgtaacctg
     4201 caatccgcta tagcaggatt gaattccatc taaaggctta ttttctgtag ggccgcccta
     4261 aataagtggt gttgatgctt aggtcctgcg caatgaaagc tcatgaaccc cgtcagatcc
     4321 ggaaggaagc agcggtaagt gatcactttt gtgtgccgtg ggggtgccta agttgagcta
     4381 actgttttgg taacgcctat ggaattaagt cgatagatgg tgtacagcat ttaatatata
     4441 aaagactaat cccttagata atgagggatt tttttattaa ttttgctaaa gagaggtaaa
     4501 aagatgcata aagcattata tagagcatat agaccacaaa aatttgaaga tgttattggt
     4561 caagatcata ttattaagac tttaaagaat caaatatata gtgataatat aggacatgct
     4621 tatttgtttt gtggaacaag aggtactggt aaaacatcta ctgcaaagat tttttcaaga
     4681 gcagtaaact gtttgaataa aataaatgaa gaaccgtgta atgagtgtga gatatgcgaa
     4741 tctgtattaa aagataatac aatggatgtt gtagaaatag atgcagcttc aaataatagt
     4801 gtagatgata taagagagct tagagaaagt gtgaaatatt ctccagccaa tgctaaatat
     4861 aaagtatata taatagatga agttcatatg ttgtctcaag gagcttttaa tgcattatta
     4921 aagaccttag aggaacctcc atcatatgta atttttatat tagcaactac agagcctcac
     4981 aaaatacctg caaccatttt atcaagatgc caaagatacg attttaaaag agttacagtt
     5041 aaagatatga cccttagaat gaaaaagatt tgtgaagatg aaggaattga tatagatgat
     5101 aaagctctta atttaatagc tagaaattct caaggagctc ttagagatgc acttagtata
     5161 ttagaccaat gtatgtcttt tggagaaagt aagatagatt ataaagatgt tgttgaatta
     5221 atgggaagcg taaatataga acaattattt gaattgtctc aatgtatagt agagcaggac
     5281 actaaaaagt ctcttgagat attaaatgaa tttgtcttat ggggcaaaga tataagaaat
     5341 cttataaatg acttaattga tcattttaga aatttaatgg tatgtaaggt ttcatcagaa
     5401 ttggatgaaa taatttcatt accagaagaa actatagaac aacttaaaat tcagtctaaa
     5461 aatatagata taaatgattt aataaggatt ttaaatatat tatcaataac tcaggatgat
     5521 ataaagtcat cttcaaatcc aagggtttta gtggaaataa ccataatgaa aattgctcaa
     5581 ccaatgtttg atgaaagtaa agaagctctt ataaaaagag ttgagaactt agaaaaaatg
     5641 attgaactgg ggaactttaa gtctgaaaaa attgggaata ataaagaaaa agagtatgag
     5701 gtcgatagag aaatagatgt aaaacaagaa aatgtagttt atgaagatgt aaaaaatgag
     5761 gacgttatac ttatagagtc atcttggaag aatatactta aacaaattaa aaaagataaa
     5821 aaaatgccaa tatacgcact cttaagtgaa gtaaaaagtt ttaatgtata ttctaatatg
     5881 ttgtatgtta tatttgatga taaatttgat tttgcaaaaa ctagactgag ctctcaagat
     5941 acaataaatt atttagaaaa aacaataaga gatgttttaa atagaagttt taatgtaaaa
     6001 atagtactga catcagaagt taaagatata aatcttgaag ttaaagagaa aaaggacatt
     6061 ggtgaggaaa tattaaagaa catagtgagt gaagagatat tagaaataaa agatagtatt
     6121 gatgaaaatg agagtaaata ataaaatact attatgatat aataataaaa tgaaaataag
     6181 tttaggagga atagtgttta tggctaaaaa aggttttgga ggcggaatga tgcctggtgg
     6241 tggaaatatg aacaacttgt taaagcaggc tcaaaaaatg caagaaaata tgcaaaaagc
     6301 tcaacaagag ttagaaagta aagaagtaga agcttcagtt ggtggaggag cagttactgt
     6361 aaaagttaat ggtaaaaaag aagttataga tataactatc aagccagaag tagttgatcc
     6421 agatgatata gaaatgctac aagatttagt tttaagtgca gtaaatcaag cattgagaaa
     6481 tattgatgat atacaagcaa gtcaaatgag taaggtaact ggaggtatga atatacctgg
     6541 gttattctag taggtggtat ttatgcaagt ttatacaggt cccataacga gacttataga
     6601 ggaattttca aagcttcctg gagtaggaag aaagactgct caaagattgg cttttcatat
     6661 tattaatatg aatactaatg atgtggaagc tttatctaaa gcgattatag atgcaaaaag
     6721 agaaataaga tattgctcaa tttgttgtaa tataacagat acagacccat gtagcatgtg
     6781 ttcaaataaa agtagagatt caagtgttat atgtgttgtg gaagatccaa gagatgtagc
     6841 agctatggag agaacgagag agtttaaagg acagtatcat gtattaaatg gagtaatttc
     6901 tccaatggat ggaattggac cagatatgtt aaaaataaag gaacttatcc aaagacttgg
     6961 caatcaggaa gtcaaagaaa taataatggc aacaaatcct actattgaag gtgaagctac
     7021 agccatgtat attgctaggt tagtaaaacc aatgggaatc aaagtcactc ggatagctca
     7081 tggtcttcct gttggaggcg atttagagta tgcagatgag gtcacaatat caaaagcact
     7141 agaaggcaga agagaaatat aaaaatcgag gttaatacct cgatttttgt agttttttga
     7201 gttaaattca aattaatttt gatttagatt tattgaataa atttcttctg tattgtataa
     7261 tttgttgtat aaatcattta aaaattttga taggggtgca acatgaaacc aattatgaac
     7321 ttagaagaac ataatgcaat gaaagaaaaa agagttaaaa aaatgaaatc aaaagataaa
     7381 cctaaatatg atgattttga ggatataagt ttttctaata agaaaaaaac taaaaaaaat
     7441 gtacgaaata aaaatgctga atttagaaat aattataaaa attatcagta tgattatgaa
     7501 gaagactttt atgaaccaat ttaatattaa ataattagaa aataaaaaat ccctaataga
     7561 taatatatat actataggga ttttatttat tttatcaacc agaaattata tttaaaatta
     7621 aattagctat attttgggct gaatttgact ttcttattga tttaatattt ctttttagca
     7681 tttctaatct gctagggtca tctattaaaa cttttagtaa tattgacaag ttatattttt
     7741 ttgtagttct aagtgctgca ccacaattag ataagaaatc aagattctct tcttcctgac
     7801 ctggtatata ataaggaact atcataggta catcttttaa aagagcctca gttgtagtaa
     7861 gtccaccagg tttgcttact aatacatcta tagaagctaa aatatcattc atcttatcag
     7921 tgtatccaag aacacataca tttttatcat gataacgaga cataagtttt ttttcgattt
     7981 tttcttttag gctttcattc ttaccagtaa ttacaagtat ttgaaagtct ctatcagtat
     8041 ccagtaattc atcaagtgtc tcttttatat ttccagcccc aaagctaccc cccataagta
     8101 aaacagttaa tttatcagga gataaattca actcagaaag aacaatatct ttatctctgt
     8161 gagagagaaa agatttttca acagggattc caaatgttct aattttactc ggttcaactc
     8221 catcaaacac caataattct tttacatatt catgaccaac aatatagtaa tcaatttcat
     8281 tttgtatcca tgtagaatga gtagtataat cggttaatac agaaataagc ggaggaacat
     8341 taatggtatt tgtataatgt ttataaaaat gctctgtgta agcatttgat tcattattat
     8401 gtaaattaaa gttttttttc aatgtactta gagcaatcat tggaaaagga tgcgttccta
     8461 tgatcaagtc tggtttttcg cttctaataa gttttttaaa ttttttagcc atgaatgtta
     8521 ttagtagatt atctttaaat tcattttttg acaaaagatt tgtttcagat aatctatata
     8581 cacttccata ggctttggga gtatatatag cagatttttc gtatcctctt gaaattattt
     8641 tatccattgt attattaact aatttcaaac tatctattat ttcacattca attggctctc
     8701 catcaagtgt tttggaagta agttcttctt taatagctag agcagcccta ttatgcccac
     8761 caccagtgga agcagacatt attaatactt ttttgctcat aataaaatcc tcctaaaatg
     8821 tagcatagta tttatattat attttgatat ataaaaactg tctttgtgaa taaggttatt
     8881 gataaattat ttttaatatt aatctaatac aagattgcaa
//
LOCUS       DAEORM030000100         8582 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.106, whole genome shotgun sequence.
ACCESSION   DAEORM030000100 DAEORM030000000
VERSION     DAEORM030000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8582)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8582)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 8582)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8582
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.106"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     misc_binding    119..330
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            493..1782
                     /locus_tag="KRH23_003613"
     CDS             493..1782
                     /locus_tag="KRH23_003613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytosine permease"
                     /protein_id="HHS5226880.1"
                     /translation="MEEEKINYALEQIPENQKRGWVAMFSVLVAIGVDLSSVILGAEL
                     AQSMPMKQAILSVIVGSFFSAILYTTCSLVGSSTSLSTSMITKYVFGEAGAKIFSLVI
                     GVSLLGWFGVQVGFFAQNAQIIIKDIFNLDVSMQILSLIGGLLMMSTAIYGYKAMEKL
                     SVYSVPFLLVLMMLTIFLAFRANGISVDDNMKSTMTFAGGVSLSMSIIIVGAIVSPDI
                     SRWAKSRRDCALSSFLGIQFGNAFMIIVSIVLVKCMGTSDIMRIFITLGIAIPGIIVL
                     TLAQWTTNTSNVYSASLSIALVLKKAPEKVLTIVLGIIATLLAVFGIYEGFIGFLNLL
                     GIVIAPVGGVYTAEYYIVKQELKGFDKGVLYKPIVKRSIVSWIIGILITYLSTYGFIT
                     LTTIAPLDGFIAGFVVQSIIGKVLCSTKNKQEIDKAV"
     gene            1836..2915
                     /locus_tag="KRH23_003614"
     CDS             1836..2915
                     /locus_tag="KRH23_003614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF917 domain-containing protein"
                     /protein_id="HHS5226881.1"
                     /translation="MRFLTEESVDKIAVGAAVLGTGGGGDPYVGKLVAKQAIKKYGPV
                     KVISLDELDDDALVVPVSGMGSPVITIEKLLSEVELTTPLEIMEKLLNRKVDVIIPIE
                     IGGINSLMPIAVAAKKGLPILDADSMGRAFPEAQMVTFYLEGYEASPAVMSDEKGNSA
                     ILYPVDGIWSERLARTLTVEMGGSSSISDYNLSGAQVKKAAIGNTLTIAETIGGFLLE
                     NKSDSKGAVENILKELCGYKLFEGKVIDIKRELKGGFTRGHAFFAGINEYDGEYSILF
                     QNENLIAKKGDTPLCITPDLIAVLDLETGFPITTERIKYGSRVMVVAFPCNEKWRTEK
                     GIETVGPGYFGYDVEYKTVEELQGK"
     gene            2936..4480
                     /locus_tag="KRH23_003615"
     CDS             2936..4480
                     /locus_tag="KRH23_003615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydantoinase/oxoprolinase N-terminal
                     domain-containing protein"
                     /protein_id="HHS5226882.1"
                     /translation="MYRVGIDVGGTNTDACILDGELKVIHSVKVATTKDVETGVYNAL
                     KKVIDESKIDHSLIKYAMLGTTHCTNAIVERKRLNNVAMIRIGKPATTAILPFIDWPE
                     DLREKIELDSILVSGGYEFDGRKINELCKDEVVEFCNRIKGKVESVAISGVFAPVNKQ
                     QEEEVAKWVREILGDIPISLSNEIGNIGILERENGAILNSALSQVGKAVSLGFEKALK
                     DLGIDAQIYFSQNDGTLMNLEYTMKYPIFTIGCGITNSIRGASFLSKVKNAIVLDVGG
                     TTSDLGVLYNGFPRESSIPVTIGGVHTNFRMPDVLTIGLAGGTCVKGEKDNIKIGPES
                     VGYRITEDAIIFGGDTLTLSDVVTKLDMAFEDRKSNVENLDKEYCNEVYKKVILKLED
                     AVDQMKTSQDDVELVLTGGGSIIVPEKLKGISNVIRPPHYTAANAIGAALGQISGDVE
                     KVYSLDKMSREDAIEDAKKEAVNKALKAGAKEDTIEVLNIEDVPLAYLPGNALLIKVK
                     VVGDLI"
     gene            complement(4643..5185)
                     /locus_tag="KRH23_003616"
     CDS             complement(4643..5185)
                     /locus_tag="KRH23_003616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
                     /protein_id="HHS5226883.1"
                     /translation="MKSYIALLRGINISGKNKIIMSELKASFVELGYSEVSTYLNSGN
                     VVFLSDVDDSKVISNTIRLMIKKQFELEIPVFIISQEELKDILNNAPNWWGDNNKEIY
                     DNLIFMFPDLSYDEFYDEVGNPKEEYEKVYHYKNAIFWSFSRKDYKKTNWWSKTASSN
                     VSDKITIRTANTVRKIVGMR"
     gene            complement(5333..5617)
                     /locus_tag="KRH23_003617"
     CDS             complement(5333..5617)
                     /locus_tag="KRH23_003617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HHS5226884.1"
                     /translation="MAKNTKQTTVHIDETLLKEVKRIGINENKSISQIINESIIDYIL
                     VYRENEDKEKNEHDKNLNETINEFKKEEEKRMQAKSAARAIAEAKKRVLY"
     gene            complement(5680..6444)
                     /locus_tag="KRH23_003618"
     CDS             complement(5680..6444)
                     /locus_tag="KRH23_003618"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lysophospholipid acyltransferase family protein"
                     /protein_id="HHS5226885.1"
                     /translation="MNNYLKFATYQLIGFTSSIPRLIKIKKNPDKFSLKEKFEFMQKQ
                     AKKSLDIVNIELNIIGKETLPKEPLLFVVNHSSMLDSFILTASVERPIGCVIADEPVW
                     RNIPIFKEWAKLLRCVYVNRKNNREGIKSIAQASQNILTGQSMAVFPEGDLTWIKEPN
                     SLVSEFRSGALKIAYKAKCPIVPLVIKNSKDTYEGYQPIGKINSVPVEVEFLEPIYDH
                     IENPRLKSSVLGENIKNKMINTIENFRKSNKTFKEF"
     gene            complement(6726..6992)
                     /locus_tag="KRH23_003619"
     CDS             complement(6726..6992)
                     /locus_tag="KRH23_003619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3795 domain-containing protein"
                     /protein_id="HHS5226886.1"
                     /translation="MIESRCGILCYECGYKEKVNCKGCTEIEKPFWGEQCLVKSCCED
                     KNLTHCGLCDTFPCEMLNQFAYDKEQGDDGKRISQCKKWAVLAL"
     gene            complement(7034..7843)
                     /locus_tag="KRH23_003620"
     CDS             complement(7034..7843)
                     /locus_tag="KRH23_003620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHS5226887.1"
                     /translation="MNKIINNILNTCKQYTYILPHKLLRQYIAHYTISIPDTSIKENL
                     TLIPDASGCMIFKFDKKGIESAFWGATTKTTIVKNDIENVLFRVFVEFRPGGVYYLTG
                     LSQRESTDLKISLEDFNTLFSLEVNSIFERTSTIKELVEQLDMLFLSYLLKSNIVDMT
                     IPILENARKQNSIMSVKNISQISCYSERHLNRIFNNSLGMSVKSYLRLLRINLVLQEI
                     QNNKIPFATLAQDIGYYDQSHFINDFKSICGVNPTTYIKNLSDFYNEKYKF"
     gene            8156..8437
                     /locus_tag="KRH23_003621"
     CDS             8156..8437
                     /locus_tag="KRH23_003621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226888.1"
                     /translation="MASKQIPRNNLEKFLRIRVLSHTGDKIHIKLPVNFAKRMIENNA
                     LDLFNGKDDVVDGKKVTEILVKAFDYDLTGEVVHLERKNGDIIKVSIVQ"
BASE COUNT         3061 a         1042 c         1381 g         3098 t
ORIGIN      
        1 gtaatagtat gaaaatttac atataaaact aaaaaatgca agtaattgac tttttaagtt
       61 gacaaaatat tgcatatata ttatgatata aatcataaat taactacaaa tcaatattat
      121 atattcgtag aagaagaaag tagcataaag gaattttaca gagagttaga tttggctgag
      181 aactaatatt ggaatttatg tgaaaaggac tttggagaat actattgtaa ttatgttaga
      241 atagtggttt aattcgcctt aagaaaatga gtgagtaaaa ttaattttta ctaataagag
      301 tggtaacacg gatttatatt cgtctcttgg atttttccaa gaggcgtttt ttattataaa
      361 cttatttcag aaaatttaaa actatatatt aaatgaaaat tataaaaata tgatagttaa
      421 taaatttata aattagaaaa ttgtaaaata tgctaaggtc agtagtttta cgatttaagt
      481 ggagggatga aaatggaaga agaaaaaatt aactatgctc tggaacagat tccagagaat
      541 caaaaacgtg gttgggtagc tatgttttca gttttagtag caataggtgt ggatttatca
      601 tctgttattt taggcgctga gttggcacag agtatgccaa tgaaacaagc aatattgtca
      661 gtaattgttg gttcattttt ttctgcaatt ttgtatacta catgctcttt ggttggctca
      721 tctacaagtt tatctacatc tatgataaca aagtatgtat ttggagaagc tggagcaaaa
      781 atattttctc tagttatagg ggtttctcta ttaggttggt ttggagttca agtaggtttc
      841 tttgctcaaa atgcacagat aataataaaa gatatattta atttagatgt cagtatgcag
      901 attttaagcc taataggtgg tctcttgatg atgagtactg caatttatgg atataaggca
      961 atggagaagt tgagtgtgta ttcagtacca tttttattag ttcttatgat gctaactata
     1021 ttcttagctt ttagagcaaa tggaatttca gttgatgata atatgaaatc tactatgaca
     1081 tttgcaggtg gagtttctct gtcaatgagt ataataatag ttggtgcaat tgtatctcct
     1141 gatataagtc gttgggctaa aagtagaaga gactgtgctc tttcaagctt tttgggaata
     1201 caatttggaa atgcttttat gataatagtt tcgatagtat tagtaaaatg tatgggaact
     1261 tcagatatta tgagaatttt tattacatta ggaattgcta taccaggtat aatagtactt
     1321 acattagcac aatggactac aaatacaagt aatgtatatt cagcatcatt aagcatagct
     1381 cttgtactta agaaggctcc tgagaaagta ttaactatag tccttggtat tatagcgaca
     1441 ttattggctg tatttggaat atatgaaggt tttataggat ttttaaattt acttggaatt
     1501 gtaattgcac ctgttggtgg tgtatataca gcagaatatt acatagtaaa gcaagaactt
     1561 aaaggctttg ataaaggagt attatataaa ccaatagtta aacgttcaat agtgtcttgg
     1621 ataattggta tattaataac ttacctttca acatatggat ttataactct tactactata
     1681 gcacctttag atggttttat agcagggttt gtagtacaat ctattattgg aaaagtgctt
     1741 tgttcaacaa aaaataagca agaaatagac aaagcagtat aaagaaattt gtttataaag
     1801 tataaaataa attagaaata tgaggagaaa gtaacatgag atttttaaca gaagaaagtg
     1861 tagataaaat agcagttggt gcagcagtgc ttggaactgg aggtggaggt gacccatatg
     1921 taggtaaatt ggttgcaaaa caagccatta aaaagtatgg tcctgtaaaa gtaataagtt
     1981 tagatgaact tgatgatgat gctttggtag ttccagtatc tggtatgggt tctcctgtaa
     2041 ttacaataga aaaattactt tcagaagtag agttaactac ccctttagaa ataatggaga
     2101 aattattaaa tagaaaagtg gatgttataa ttcctataga aataggaggg ataaactcac
     2161 ttatgcctat agcagttgct gctaaaaaag gacttcctat cttagatgca gattctatgg
     2221 gtagagcttt ccctgaagct caaatggtaa ctttttatct tgaaggatat gaggcatctc
     2281 ctgccgtaat gtctgatgaa aaaggtaatt ctgccatcct ttatcctgtg gatggaattt
     2341 ggtcagaaag attagctaga actttaactg tagaaatggg aggaagttct tctattagtg
     2401 actataattt aagtggagct caagttaaaa aagctgctat aggtaatact cttacaatag
     2461 ctgaaactat aggagggttt ttacttgaaa ataaatctga ttcaaaaggt gctgttgaga
     2521 atatactaaa agaattgtgt ggatacaagt tatttgaagg aaaagtaatt gatattaaga
     2581 gagagttgaa aggtggattt actagaggac atgccttttt tgctgggatt aatgagtatg
     2641 atggagagta ttctatatta ttccaaaatg agaatttaat tgccaaaaaa ggtgatacac
     2701 cactttgtat tacaccagat ttaatagcag tattagattt agaaactgga tttccaataa
     2761 ctacagagag aataaaatat ggctctcgtg ttatggtagt agcttttcct tgtaatgaaa
     2821 aatggagaac agaaaaagga attgagacag ttggacctgg atactttgga tatgatgtgg
     2881 aatataaaac agtagaagaa ttacaaggaa aataaaagtt taggaggaaa ttttgatgta
     2941 tcgtgtagga attgacgttg gaggaacaaa tacagatgct tgtatactgg atggggaatt
     3001 aaaagtaatt cattcagtta aggtggcaac tacaaaagat gttgaaactg gtgtttacaa
     3061 tgccttaaaa aaagttatag atgaaagtaa gattgaccat tcattaataa aatatgctat
     3121 gcttggtaca actcattgta caaatgctat tgtagaaaga aaaagactta ataatgtggc
     3181 tatgataaga ataggaaagc cggccactac tgccattctt ccatttatag attggccaga
     3241 agacttaaga gaaaaaatag aattagattc aatattggta tctggtggat atgagtttga
     3301 tggcagaaaa ataaatgaac tttgtaaaga tgaagttgta gagttttgca atagaataaa
     3361 aggcaaagtg gaaagtgttg caataagtgg agtatttgct ccagtaaata aacaacaaga
     3421 agaagaagtt gcaaaatggg ttagagaaat tttaggggat attcctatat ctttatcaaa
     3481 tgaaataggt aatataggta tattagaaag agaaaatgga gctattttaa attctgcatt
     3541 gtctcaagta ggtaaagctg tatctttagg atttgaaaaa gcacttaaag acttaggtat
     3601 agatgctcaa atatatttca gtcaaaatga tggaacatta atgaatttag agtatacaat
     3661 gaaataccca atttttacaa ttggatgtgg aataacaaat tctataagag gagcttcctt
     3721 cttatcaaaa gtaaaaaatg caatagtatt agatgttggt ggaactacaa gcgacttggg
     3781 tgtactatat aatggattcc ctagagaatc atctattcca gttacaattg gaggagtaca
     3841 tacaaacttt agaatgccag atgttttaac tattggtctt gctggtggta catgtgtaaa
     3901 aggcgaaaaa gataatataa agataggtcc tgaaagtgtg ggatatagaa taactgaaga
     3961 tgcaataata tttggtggag acactctaac tttatcagat gttgttacaa aattagatat
     4021 ggcgtttgaa gatagaaaaa gcaatgttga aaacttagat aaagagtatt gtaatgaggt
     4081 atataagaag gttattttaa aattagaaga tgctgtagac caaatgaaga ctagtcaaga
     4141 tgatgttgaa ttggttttaa ctggtggagg aagtataatt gttcctgaaa aactaaaagg
     4201 cataagcaat gttataagac ctcctcatta tactgctgca aatgctattg gtgcagcttt
     4261 aggacaaata agtggagatg tagaaaaagt atacagttta gataaaatgt cgagagaaga
     4321 tgccatagaa gatgcaaaaa aagaggctgt aaataaagct ctaaaagctg gtgctaaaga
     4381 agatactata gaagtattaa atatagaaga tgttccactt gcataccttc ctggtaatgc
     4441 acttcttata aaagtaaaag ttgttggtga tttaatttaa agaataaata taagtatttc
     4501 cagaattata taaatatttc tggactcatt tttaaactta ttttatcaat aaaaacagca
     4561 taacttttga ctatattctt ataagtttcc gaacagccga tatataccta ttttttgagg
     4621 tttatcggct gtttgttatc ttttatcgca ttccaactat ttttcttacc gtatttgctg
     4681 tacgaattgt aatcttatca cttacatttg aactggcagt ctttgaccac caatttgtct
     4741 ttttataatc tttacgacta aaagaccaaa agatagcatt tttataatga tatacttttt
     4801 catactcttc tttaggattt ccaacctcat cataaaactc gtcataagat aagtcaggaa
     4861 acataaaaat aagattatca tatatttctt tgttgttatc tccccaccaa ttaggagcat
     4921 tatttagtat atcttttaac tcttcttgtg aaataataaa aactggtatt tccaattcaa
     4981 actgtttttt tatcattaat cttattgtat ttgagataac cttgctgtca tctacatcac
     5041 ttaaaaagac aacattacca ctattaaggt atgtagaaac ttctgaataa ccaagttcta
     5101 caaagcttgc ttttaattca gacataatta tcttgttctt accacttata ttgatacctc
     5161 ttaataatgc gatataactt ttcatataat aatttcacct ctaaacattc acatttttct
     5221 atgtagtaca aacttgaatt tgcatctttt ataattcttt caaaacttct tcatatgtaa
     5281 tttttttaat ataaaaaaat cggtgcttaa tttgtaccga tttttgtttt tcctagtaaa
     5341 gaactcgttt ttttgcttct gctatagctc tagcagcact ttttgcttgc attctttttt
     5401 cttcttcttt tttaaattca tttattgttt catttagatt cttatcatgt tcattttttt
     5461 ctttatcttc gttttctctg tatactaata tataatctat tattgattcg tttattattt
     5521 gagatatact tttattttca ttaattccta ttctcttaac ttccttaagt agagtctcat
     5581 caatatgaac cgttgtttgc tttgtatttt ttgccacctt aatcacctct taaaaaaaat
     5641 tctaacatta aaattttttt tagtcaataa attttaatat taaaattctt taaatgtttt
     5701 atttgatttt ctaaaatttt ctattgtatt tatcatctta ttttttatat tttcacctag
     5761 tacagaagac tttagtctag gattttcgat atggtcataa attggttcta aaaattcgac
     5821 ttcgacagga acagagttaa ttttaccaat aggttggtat ccttcataag tatcttttga
     5881 attttttatt actagtggaa caatagggca ttttgcttta tatgctatct ttaaagctcc
     5941 acttctaaac tccgaaacca atgaatttgg ttctttaatc catgttaaat ctccttctgg
     6001 aaacactgcc atactttgac ctgtaagtat attttgagag gcttgggcta tactctttat
     6061 accctcacga ttgttttttc tgtttacata tacacatctt agtaattttg cccattcttt
     6121 aaatataggt atatttctcc aaactggttc atctgcaatt acacatccaa ttggtctttc
     6181 tacacttgct gttagtatga agctgtcaag catactagaa tgatttacaa caaatagaag
     6241 tggttctttt ggtagtgttt ccttaccaat tatattaagc tctatgttca ctatatctaa
     6301 agatttttta gcttgttttt gcataaattc aaatttttcc tttaagctaa atttatcagg
     6361 attcttttta attttaataa gcctaggtat agaagatgta aaacctataa gttgatatgt
     6421 agcaaatttt aagtaattat tcataaaatt atctccttaa aataaaatta tttattactg
     6481 taaagatttt aacataaaat aaaatttaag tctattttaa ttcaattttg taacatatat
     6541 tttaaataga cagagattga gattttatat ttccaatttt agtaatcaga ttttatcaat
     6601 aaattactat tctattaatt taattaaata acctttaaat ttaattataa aaactgttgc
     6661 agaaatttct acaacagttt aaaaaattta ccttacaaaa acttatttta taacaagaga
     6721 gtatattata aggctagtac agcccatttt ttgcactgag aaattctttt gccatcatca
     6781 ccttgttctt tgtcatatgc aaattgatta agcatttcac atggaaatgt atcacataga
     6841 ccacaatgtg taaggttttt atcttcacaa caagatttta caagacattg ttcaccccaa
     6901 aatggtttct caatctctgt acaaccttta caattgactt tttccttgta tccacattca
     6961 taacataaaa ttccacatct tgattctatc attttaagtc actccttaaa tataaatttt
     7021 atatgattgt atatcaaaat ttatactttt cattgtaaaa atcggacaaa ttttttatat
     7081 aggttgttgg attaacacca caaatagatt taaaatcatt tataaaatga gattggtcgt
     7141 aataaccaat atcttgtgct aaagttgcaa agggtatttt attattttgt atttcttgta
     7201 atacaaggtt tatacgaagt aatctaaggt atgatttaac actcatacca agagaattat
     7261 taaaaattct atttaaatgt cgttcactat aacaactaat ttgtgaaatg tttttaacag
     7321 acataataga gttttgtttt ctagcatttt caagaattgg tatagtcata tctactatat
     7381 ttgatttcaa taagtatgat aagaataaca tatctaattg ttctactaat tcctttatag
     7441 tacttgttct ttcaaaaatg gaattaacct ctaagctaaa taatgtgtta aaatcttcaa
     7501 gtgaaatttt taaatctgta gattctcttt gagaaagacc tgtcaaataa tatactccac
     7561 ctgggcgaaa ctcaacgaat actctaaaaa gtacattttc tatatcattt tttacaatag
     7621 tagtttttgt tgtggctccc cagaatgcgc tttctatacc ttttttgtca aatttaaata
     7681 tcatacatcc actagcatca ggtattaatg taagattttc tttaatactt gtatctggaa
     7741 tagatattgt atagtgtgct atatactgtc ttaacaattt atgtggcaaa atatatgtat
     7801 actgtttgca ggtatttaaa atgttattga ttattttatt cataagtata tcctcctgat
     7861 atataaaaaa taagtatact aatttatttt ttatataata aaccagtttt gttttaattg
     7921 aaatattcta ataagatatt ttgttaaatt tagatacaat aattgtaaag taaaatctca
     7981 aaatatacaa ttattataaa tcatagatat ttattaaata aatatattaa agaagaagga
     8041 atataaaaca agattagaaa ataatagtgt tactttcata ataaatacat ataaagatat
     8101 ttttaagaat aaaatttatt attaaataaa aaataaagga gagtgattta atagcatggc
     8161 atcaaaacaa ataccaagaa acaatttaga aaagttttta agaataagag tcttatcaca
     8221 tacaggcgat aaaatacata taaagttacc tgtaaatttt gcaaagagaa tgattgagaa
     8281 taatgctttg gatttattta atggaaaaga tgatgtagta gatggtaaaa aagttactga
     8341 aatattagtt aaggcatttg actatgattt aactggagaa gtagttcact tggagagaaa
     8401 aaatggagac attattaaag tttcaattgt acaatagaat tattttatat gaattttatt
     8461 tttgaatagt tataaataat tagaaatttg taaaaaagta taatatatta ttagtaatgg
     8521 tacagaatac acatttataa tttatagatg tgtatttttt gtttaaaaaa tttaaatata
     8581 ta
//
LOCUS       DAEORM030000101         8439 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.107, whole genome shotgun sequence.
ACCESSION   DAEORM030000101 DAEORM030000000
VERSION     DAEORM030000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8439)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8439)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 8439)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8439
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.107"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            complement(465..1313)
                     /locus_tag="KRH23_003622"
     CDS             complement(465..1313)
                     /locus_tag="KRH23_003622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SHOCT domain-containing protein"
                     /protein_id="HHS5226889.1"
                     /translation="MWILVPIITIVLLIIAVSSMQYILVMIAFLLIIYSFIEKKIVMG
                     LVSVLFFTYSIYLCATCEDKSLIADNKVETVKAQRETVEREKEMERRRIQEEVDKERY
                     IEKHGMEISENDLKVKLEALVPQEYKGKKYELKVGKFKRYSMYFDLTVQNEKFSNSEE
                     CKKFVKEIANDLKKIKISKAYFKFHSKDDGGIYNSVYIDYFRNIQNNVDNVENLEFNE
                     FELKTEEEEKREQEKIEQEKNSYNNYIQNRVVDPLDRIKKLKELLDSGAITQEEYNKK
                     KKELLE"
     gene            complement(1581..1733)
                     /locus_tag="KRH23_003623"
     CDS             complement(1581..1733)
                     /locus_tag="KRH23_003623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA];
                     GO_function: GO:0090729 - toxin activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin"
                     /protein_id="HHS5226890.1"
                     /translation="MDNFLFNVLASVTASYIVYLISKLIKKVKSHSTAKSDLKIDINF
                     KYHRKK"
     gene            complement(2007..2330)
                     /locus_tag="KRH23_003624"
     CDS             complement(2007..2330)
                     /locus_tag="KRH23_003624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6054 family protein"
                     /protein_id="HHS5226891.1"
                     /translation="MARDVFSVKMTPLEAQKMVEKNLEADLISVDIYNLENNKSIIVT
                     IFEKYYARSNSDAGLVVICENTTGKTLVKITSTGSAIGLFQIDWGTGNNLIKRVKKIL
                     IDYII"
     gene            complement(2366..2635)
                     /locus_tag="KRH23_003625"
     CDS             complement(2366..2635)
                     /locus_tag="KRH23_003625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226892.1"
                     /translation="MRGVFIENKDIKLTICIFAFVIGIIVLFCCIGLGQFNMDCIIKQ
                     NGGSIATEQYNIYLEQSISQYRNFGSILALLGGIGILFDKSVRKY"
     gene            complement(2916..3425)
                     /locus_tag="KRH23_003626"
                     /pseudo
     CDS             complement(2916..3425)
                     /locus_tag="KRH23_003626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888399.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-guided endonuclease TnpB family protein"
     gene            complement(3715..4090)
                     /locus_tag="KRH23_003627"
                     /pseudo
     CDS             complement(3715..4090)
                     /locus_tag="KRH23_003627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430377.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
     gene            complement(4195..4572)
                     /locus_tag="KRH23_003628"
     CDS             complement(4195..4572)
                     /locus_tag="KRH23_003628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HHS5226893.1"
                     /translation="MKEEILIEKLLRAELIVMEYLWKKDTLMPKKEIVKEIKQIYGWH
                     KSTIKILLKRLVDKRYLDRYIINFQSYYKIIIDNKEYYTFKKKVLKSSKSIKIMHSLT
                     TIHKNVSKEKLDLLDEYYRNLKE"
     gene            5377..5871
                     /locus_tag="KRH23_003629"
     CDS             5377..5871
                     /locus_tag="KRH23_003629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0015627 - type II protein secretion
                     system complex [Evidence IEA];
                     GO_process: GO:0015628 - protein secretion by the type II
                     secretion system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HHS5226894.1"
                     /translation="MKNKKGFTLVELLVVIAIIGILAIVALPALFKNIEKAKIAKLEA
                     DISAIKSASLSYYADESKYTDGGMISWVKKDGKIIINGGFKDDPLADKIENLGMPYNG
                     SYLLMSSPGHEKYLELSILPEGEISKSGLDKLKSDYGSSIDIMNEQNKIDIVIKFLND
                     KSNT"
     gene            6230..6430
                     /locus_tag="KRH23_003630"
                     /pseudo
     CDS             6230..6430
                     /locus_tag="KRH23_003630"
                     /inference="COORDINATES: protein motif:HMM:TIGR04223.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(6907..7095)
                     /locus_tag="KRH23_003631"
     CDS             complement(6907..7095)
                     /locus_tag="KRH23_003631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226895.1"
                     /translation="MTKYDFNFKLKIAKFYLNREGRDILIVKQYGVYNHSQVERWVNI
                     LGESELKIKNFSILYGSS"
     gene            7257..7607
                     /locus_tag="KRH23_003632"
     CDS             7257..7607
                     /locus_tag="KRH23_003632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3796 domain-containing protein"
                     /protein_id="HHS5226896.1"
                     /translation="MIQKKFFMGFCGFLGFLSLRYFSSGNVADLTYIGFFAFFSNFII
                     AKINGDKADERYVQDEKAAMAFTGQLAIIELFILWCITIVSRNIELMCVLLSITYAIT
                     LNVYAIKLYILEEK"
     gene            7609..7809
                     /locus_tag="KRH23_003633"
     CDS             7609..7809
                     /locus_tag="KRH23_003633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HHS5226897.1"
                     /translation="MPKFICNLKKYRQLKELTQEQLAEKVGVRRETIMRLEAGKYNPS
                     LKLAIDISKIVDTPIDELFIFD"
     regulatory      7989..8078
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            8132..8308
                     /locus_tag="KRH23_003634"
     CDS             8132..8308
                     /locus_tag="KRH23_003634"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226898.1"
                     /translation="MFRDKMDKCTHMLTAYIGSSYDYCDFIDTQLDDFILEYGEKVVE
                     SCLHQVMVLVSKYN"
BASE COUNT         2897 a         1167 c          894 g         3481 t
ORIGIN      
        1 acgataaaag atgattgatt acaagctttg ttcagaattt acattccata tagttaatct
       61 aaaacattat tcaaaatagg taattcccat ctgggagcaa catttacatt ccatatagtt
      121 aatctaaaac tcgcaaatca gaaaattctt cagacattcg ataataaaaa tttacattcc
      181 atatagttaa tctaaaaccc caaaataaac ttagcatttc caatacctac atatatacaa
      241 tactcttaaa attgcagtga gcgggcaata gtgcaattga taacacttat cacgcaccct
      301 caacatctta gatttcaagt attaagccct actttgtaac aaatatcgca cactgcaaaa
      361 cttctatatt tttattatat cataaaatct aaactataaa attaaaatgg aatactttgt
      421 aaatttaaaa gcacctacat acttgtaagt gcttactata ttatctattc taataattct
      481 tttttctttt tattatattc ttcctgtgta attgctcctg aatctagcaa ctcttttagt
      541 ttctttattc tatctagtgg gtcaaccact ctgttttgaa tgtagttatt ataactgttt
      601 ttttcttgtt ctattttctc ttgttctcgc ttctcttctt cttcggtttt aagttcaaat
      661 tcattgaatt ctaaattttc aacattatct acattatttt gtatgtttct aaaataatca
      721 atataaacag aattatatat accaccgtca tcttttgaat gaaacttaaa gtacgccttg
      781 cttattttaa tttttttaag atcattagca atttctttta caaatttttt acattcttca
      841 gaattactaa atttttcatt ttgtacagtt aaatcaaaat acatactata tcttttaaat
      901 tttcctactt ttaattcata tttcttcccc ttatattctt gaggtactaa agcctctagc
      961 ttaactttta aatcattttc tgatatttcc attccatgtt tttcaatata tctttctttg
     1021 tctacttctt cttgtattct tcttctttcc atttcttttt ctctttctac agtttctctt
     1081 tgtgccttaa cagtctcaac tttattatct gctatcaagg atttatcttc acaagttgca
     1141 caaagataaa ttgaataagt gaaaaaaaga actgacacaa gacccataac tattttcttt
     1201 tctataaaag aatatataat caacaaaaaa gctatcataa ctaaaatata ttgcatagaa
     1261 gaaacagcta ttataagtaa tactattgtt attattggta ctaatatcca cattgtaaaa
     1321 ttccccacaa attactcatc tcactcaata ttatagcata atttggcaaa acaaaagcac
     1381 ctaccattta agtaagtact ttcttattta caattaaatt tattcatcta gttagattca
     1441 tcatcattgt gtataaaaaa attcatcttt ttattgacta taaaaaatat tatatgcaat
     1501 attttttcta atttgtggta taataaaagc aagaagaact acaatctatt tgcggtagag
     1561 tgaagttcta taactgaaag ttatttttta cgatgatatt taaaatttat atcaatcttt
     1621 aagtcactct ttgcagtaga gtggcttttt acttttttga ttaacttgct aatcaaataa
     1681 actatgtaac tagctgttac actagctaac acattaaata aaaaattatc catgtatatt
     1741 cacctccctt cttatcgttg ggagaataat tttttaatac atgaactcca ctctataaat
     1801 tgtagattac atcttcttgc tacaattatt ataatatata attcttatat atttttccta
     1861 tatcttactt tttattttat tttctatttt ttcaataaaa agcacctaca tatttgtaag
     1921 tattttctat gtttatttag ttttattgat tacttaatag gttagtacaa attccatatc
     1981 aacctaagaa tatctacata aaataattaa ataatataat caataagtat ttttttcact
     2041 cttttaatca aattattacc tgttccccaa tcaatctgaa atagtccaat tgcactacca
     2101 gttgaggtaa ttttaacaag tgtttttcct gtagtatttt cacaaatcac taccaaacct
     2161 gcatcactat tgcttcttgc ataatatttt tcaaagattg taactattat agacttatta
     2221 ttttctaggt tataaatatc aacagaaatt aaatctgctt ccaaattttt ttctaccatt
     2281 ttctgtgctt ctagtggtgt catctttaca ctaaatacat ctcttgccat atcattcatc
     2341 acatcctaaa taaaaatata cttttttagt attttctgac acttttatca aacagtattc
     2401 ctattcctcc tagtaaagcc agtatagaac caaaatttct atattgtgaa atagattgtt
     2461 ctaaatatat gttgtattgt tcggtagcta ttgacccacc attttgtttt ataatacaat
     2521 ccatattaaa ttgacctaga cctatacagc aaaataacac tattattcca attacaaaag
     2581 caaatataca tattgtaagt ttaatatctt tattttctat aaatacaccc ctcataattt
     2641 agatttattt gttgtttttt acttggtgat atattatcta cattatacta tacaacatat
     2701 atatccatct atttccaaaa ttgtaacatt ttcatatatt agcaatgtga ctattttaac
     2761 tttaaattct accttcttct acctctcttt ttctctcttt cagcttcttt cattgcttct
     2821 tcttcatctt caattttaat aagtattgag tcggctgcta atgctctctc attaacttct
     2881 aaattcatat attcactagg tttccacttt agcttttgaa tgcaatttag tcttaatcct
     2941 tcttttaata tatttatact tgcatttata tctctatcgt gagtttcatt acaactagga
     3001 taaatccatt ctcttatatt taagtccttc acttcctcgt ttttataccc acatttattg
     3061 catatttgtg aacttgcaaa gaatttaccc acctttacaa tttgtctacc atgccaatta
     3121 gccttgtatt ctaattgacg aataaactct gaccatgaca catcagaaat tgagcgagat
     3181 agtttacgat tcctaatcat attctttact tgtaaatctt ctatgcaaat aatatcgttc
     3241 tcttttatta atttagtaga tagtttttgt agaaaatcat ttctttgatt agctatatgt
     3301 tcttgaagtc ttgcaacttt taatctcgct ttatttctat ttaaactacc gattgttttt
     3361 ctcgataatt ctctttgtaa tttagcaagt ttgtttaatg acttcttaag atttgagata
     3421 aattgaggtt tatttgaata aattgatttg aattatgtta ttttcagatt acttttattt
     3481 aagtattttg attggattca gctgaattaa tgtatattaa ttcttattga acagttttta
     3541 tttttataca tactatctac tatatcctat acatattcta ctaaaattta tataaatatt
     3601 agacaaacct attttatttt cttaacatgt tcagaataat aaacaaaatg aaggtagaaa
     3661 aagttataat ttcatacctt ctttttattt attatgtatc aatttgtcat tttcttattt
     3721 caaattctta aaatattctt ctaataaatt taaaatatca ccatctactt catcatcctt
     3781 actacatagt gctgacatta aacttaatat tgaattttta tgtgtattct ttaaaaattc
     3841 ttttgtttaa aatctctgat attatttttc ttttactaat acattatagt gtgtacactt
     3901 atctattttc tccgtttcta aaaactctct tctttagtaa tctttttaat actgtaaata
     3961 tagttgtatg tttccattca tatttttgtt ccatagactt ggtgatttct cttgatatta
     4021 ataccttttc tgattcccaa atatatctca taacttttaa ttccgcttct ggtaatttac
     4081 taattttcat agtatacatc cctttaccaa tttatgtata tgtcaaattc tatatcaata
     4141 aagttttaca aacaaaggaa ttaaggtaaa taattacatt cgatttttac tatatcattc
     4201 ttttaagttt ctataatact catctaatag gtctaacttc tctttactta catttttatg
     4261 tatagtggta agtgaatgca ttatttttat gcttttacta gattttagta cctttttctt
     4321 aaaagtataa tattctttat tatctattat tattttataa taagattgaa aatttataat
     4381 atatctatcc aaataccttt tatcaactag cctttttagt agtattttta ttgtactttt
     4441 atgccatcca taaatctgtt ttatttcttt tacaatttct tttttaggca ttagagtgtc
     4501 ttttttccat aaatactcca ttactattaa ttctgctctt aataattttt ctattaatat
     4561 ttcttctttc aatttatgtc acttccttaa ttcttctaac ttaaattaat aataggagct
     4621 ttttaagaca aaaactagag gtaagtttta ccaaatattt tacgtattta gtctgttttt
     4681 ttaaacgtaa aataatattc atatatataa atttgtttaa tttgcaaaca atgctaccaa
     4741 acaataaata gctctattgt attattttag ttgtagaata gcactaaatc gctagaatca
     4801 aagaaattta gtagcacaaa gctatatagg ctaatgctta taaaataaat tataagttat
     4861 gttaacaagt tactaaaagc atattttatt tttgttttta tgaaagtttt ttaggtatgt
     4921 aataatatat atcttttaaa atatgtattc atgtatacat attttgactt attatactga
     4981 tagttcatat aattatttta attttataga tacacagtta gatgatttta tactagagca
     5041 taaaaaaaat gtagtataat cttgtttata tcaagttacg gtattggtaa gtaagtataa
     5101 ttaaatagac attattttct gagtcctctt tttattttca tctgctttta aataatatta
     5161 ttgacattga tatgactgta gttttcttta ttttaatcca tttcttatat cttttctaac
     5221 aagaaatgtc attttaaatc atttccacaa attgtaaaat aatagtgtat ttgtcataga
     5281 aagtgatttt tttgtctata tatggtaaaa tatagaaagt agaaatcaac aaaataaaaa
     5341 tttatatatt attaatttta tatggagggg aaataaatga aaaataaaaa aggatttact
     5401 ctagtggaat tattagtagt aattgctata ataggaatat tggcaatagt agcacttcca
     5461 gcattattta aaaatataga aaaagcaaag atagctaaac ttgaagctga tataagtgca
     5521 ataaaaagtg cgtctcttag ctactatgca gatgaatcaa aatatactga tggaggaatg
     5581 atatcatggg taaagaaaga tggaaaaata ataataaatg gtggctttaa agatgaccca
     5641 ttagcagata aaatagaaaa tttaggtatg ccttataatg gttcatatct attaatgtca
     5701 tctcctggtc atgaaaaata tctagaatta agtatacttc cagaaggaga aataagcaaa
     5761 agtggtctag ataaattaaa aagtgattat ggaagttcaa tagacataat gaacgagcaa
     5821 aacaaaatag atattgtaat aaaattttta aatgataaat cgaatactta aatacaataa
     5881 attttattta ataattgctg atgaaataaa caatcttgtt tggagaaatg aaaaaagcac
     5941 tcctcaagaa tagaatgctt agttataatt acagaagtgt attggcatac acttctattt
     6001 tttattatat cacataattt aaaaatacct attcaagttg tttttaaatt atgttgagta
     6061 atattcttga tagtttatac attaatgaat ttcaaaaaaa taagtactct ttataataaa
     6121 aagtacttta atgtatgtta atgtcctatc taataaaatt gtaacatgcc ttatgcttta
     6181 gtatgataat tttcattttc tttattgttg caacttatac tatagttttg ctaatttatc
     6241 tgcaaacaca acttctttat tgcatgtgta tcaaccaaaa acatcagaat acttacttaa
     6301 tacatatgca aaatcgtatc tttcatctat agtattctta tttgactata taacaaaaaa
     6361 tgaatcgaga tatgcctttt ttataattaa ttttccattt ttatcattag atatatttta
     6421 taaattctag catatcattt gttattttct gatatgctat tgatgtttta aatcttctat
     6481 ttgttttatt attttttact tttccaatta tacatttata ggagttatat ttatgtgatt
     6541 tatgaaaaaa tactatgcat ttaagttcta attttttgat aatacatcta acttactttt
     6601 gattaataat gataccactg ttttttaatg tggcttccct aaggcacaca tcttttttaa
     6661 aaactcaagc tcatctttta aaaatttatt ttcatattct aattcttgtt ctcttgttaa
     6721 tttatttttt ctttagtgtt tttgttttta ttcattatgg tcttcctttc attttggaaa
     6781 aggcatcaac accactatgt aaaaattttt attttcatgt tgctataact gtgctattgt
     6841 ttattccaaa atacttagcg atttattgta cactatattt agttatcatc atatagttta
     6901 taacatctaa cttgaaccat atagtataga aaaatttttt atttttagtt cactctctcc
     6961 taatatatta acccatcttt caacttgaga atggttataa actccatatt gttttactat
     7021 taaaatatct cttccttctc tattcaaata aaatttagct atttttaatt tgaaattaaa
     7081 atcatattta gtcatacata aacatctcaa gcgttagatt tttgctctaa caattatggt
     7141 gcagtataaa tattgtataa tactgatttt atattgacaa aagaatataa aagagatata
     7201 tttgtatcat aaagatataa atatatctct tttaaaatta ctaaggagga taaaaaatga
     7261 ttcagaaaaa attttttatg ggtttttgtg gtttccttgg atttttaagt cttagatatt
     7321 tttcatctgg caatgttgct gaccttacat atattggatt ttttgctttt ttctcaaact
     7381 ttattatagc aaaaataaat ggtgataaag cagatgaaag gtatgtacaa gatgaaaaag
     7441 cagctatggc atttacagga cagcttgcta ttatagaatt attcatttta tggtgtatta
     7501 ctatagtgtc taggaatata gaattaatgt gtgttttact atcaattaca tatgcaatca
     7561 ctttaaatgt ttatgctata aaactttata ttttagagga aaaataatat gcccaaattc
     7621 atttgtaacc taaaaaaata tagacaatta aaagaattaa ctcaagaaca attagcagaa
     7681 aaagtaggag ttagaagaga aaccattatg cgtttagaag caggaaagta taatccttct
     7741 ttgaaattag caatagatat atcaaaaata gtagatacac ctattgatga attgtttatt
     7801 tttgattagt ttttgcatta ttaaaaatgt gttttaaata caaacttaaa ttcaattttt
     7861 aagtcactcc tgacagaggg gctttttatt ttttcaaata atttaacatt catatataaa
     7921 tttattaatt tttcagctag atatgttgaa taataactaa ttctattgta ttattaatct
     7981 gtagaataaa actaaatcgg caaaactaga gaaatttagt gacgcaaagc tatagggact
     8041 aacgcttata aaataagtta tgtcagccag ttgccaaaaa gatattttct ttttgttttt
     8101 catgaaagtt ttttaggggg ataaatacat tatgtttaga gataaaatgg ataaatgtac
     8161 acatatgtta actgcttata ttggtagttc atatgattat tgtgatttta tagatacaca
     8221 gttagatgat tttatattag agtacggaga aaaagttgtg gaatcttgct tgcatcaagt
     8281 gatggtattg gtaagtaagt ataattagac agattttttt ctagaaaacc ctttttagtt
     8341 ttatctacat ttacattaat atattggtaa tataaaatgt ttaaatttat tttcatatta
     8401 agaataaata aaaatgttaa ctaaaaatta taattaaat
//
LOCUS       DAEORM030000102         8429 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.108, whole genome shotgun sequence.
ACCESSION   DAEORM030000102 DAEORM030000000
VERSION     DAEORM030000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8429)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8429)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 8429)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8429
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.108"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            231..1310
                     /locus_tag="KRH23_003635"
     CDS             231..1310
                     /locus_tag="KRH23_003635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HHS5226899.1"
                     /translation="MPELLKNMYNRESLYEVAVAIQSVYNSFKVDEFIKSTMDETWNN
                     LELKARCRKISMSLGMYLPEDYKEALSILEKSVTGFYFAFFFPDFVEVYGQDDVNWDL
                     SISALERNTEYWSSEFAVRAFIIKDEERMMAQMRKWSKHKSEHVRRLASEGCRPQLPW
                     GQAISKFKKDPTPVLPILEQLKTDTSTYVQKSVANNLNDISKTHPDLVISIAKDWYGK
                     NKSTNWIVKHGCRTLLKKGNRDVLALFGYDDTTSINIQDFTLETTSISIGENLTFSFN
                     ILAKKATKTRLEYGIDYVKSNGKRNRKIFKISEVSLKENEKKSYMKKHSFADVSVRKH
                     YPGIHSITIIINGVEKGKLDFELGV"
     gene            1634..2002
                     /locus_tag="KRH23_003636"
     CDS             1634..2002
                     /locus_tag="KRH23_003636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HHS5226900.1"
                     /translation="MDVYSFWNDTLAQDAVKIRKYFHEDAYINWHDTNEHFTLEEFII
                     ANCEYPDKWNGKVERVLEFGNLVITVTHVYAINKPLSFHVVSFISLKDDKIISIDEYW
                     GEDDDVPQWRLDKHIGKPIK"
     gene            2119..2916
                     /locus_tag="KRH23_003637"
     CDS             2119..2916
                     /locus_tag="KRH23_003637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HHS5226901.1"
                     /translation="MEEKYILSDRGKVYYWIKESNSVFAKNLIFLPGLTANHHLFDFQ
                     IQYFSKNHNVLVWDAPAHGKSRPYLDFSYSNLVEELKVILDRQNMKKVVLIGQSAGGF
                     VAQSFIVKYPNMVEGLMMIGTCPYGTDYYSKSDIFWLKQTEWMLKLFPDKLLRNIISK
                     MCGATSEGRRSMLKMLEGYEKKELCHLMYLGFAGFIPEIQDLNIHCPVCLVVGDKDKT
                     GKVRKYNEQWHNKTGYPLHIIKNDSHNVNVDKPNELNQIMDIFIKQL"
     gene            3308..4198
                     /locus_tag="KRH23_003638"
     CDS             3308..4198
                     /locus_tag="KRH23_003638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HHS5226902.1"
                     /translation="MIESIPAKQILQKVKFDNTRWFGIDYNMNLYRGCSHGCIYCDSR
                     STIYNIENFDKVRYKENVIEILSKELRSKRKKGVVGIGAMSDTYNPFEKQLCITKQAL
                     DLISENHFGVSIDTKSSLVVRDIPILKKIKKNNSAIVKLTITTANDELSKKIEPYVNP
                     SSVRFDAVKELNDSGIFCGILLTPMLPFLTDTKDEIRAIVEKAHKANAKFIYCMYGVT
                     MRSDQREFFYEHLRDISPKLVLKYQKTYGLNYVCTVQNKDCCEKLLREECARYGILTD
                     MKEIIKAYKRSESYTQIKFF"
     gene            4462..4905
                     /locus_tag="KRH23_003639"
     CDS             4462..4905
                     /locus_tag="KRH23_003639"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HHS5226903.1"
                     /translation="MVEIKTIEINKKGQIDLLMLADPCEEMIDKYLNKGTMYALYDNK
                     ELTCIAVVNEISKEICELKNIATYEHFQNMGYASKMIYHLLDVYSKKYSSMVVGTSES
                     GVPFYEKFGFVYSHKIKNFFVDNYPEPIFEGELQCVDMLYLSYNF"
     gene            5073..5243
                     /locus_tag="KRH23_003640"
     CDS             5073..5243
                     /locus_tag="KRH23_003640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226904.1"
                     /translation="MDSNNNTIKSTVKKGISFGSCLAMIISYTAWKSIPWAIFHGLMS
                     WIYVLYYWVKYA"
     gene            5617..6726
                     /locus_tag="KRH23_003641"
     CDS             5617..6726
                     /locus_tag="KRH23_003641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="HHS5226905.1"
                     /translation="MKEKLEEKSKIIKTSKEYKRTVIEEKDREWTKKLNDILSRGDFS
                     NEKLDKIKDLIPKEILTSENVGEVVTEDGYAKPEYDEVFKSLFTLNNDYDLLANFIND
                     ILKDAPYANRNIKPFTHIKRIIKAETDPTINYIGEKRPRLDILAEDEESNHINIEMQR
                     ALEDDYLERAEYYLSRVHGRKLEEGKEYKEIGKTIGIHILNHVKYNHIEDYVNCLRLT
                     MDGHPDIYSSKTALYFIELPKIRKSSCIANRVLIWGKLIDNPSHIDIRILSKTDYVIK
                     RALDRLKELGSNEEYLLNLKRGAYIMNKSRNFKEEIFQEGVEKGIAKGIAKGKREEKF
                     NIIIKLKNKGYNLSEICDIIDDLNKSEVEKIYNQN"
     gene            6907..7395
                     /locus_tag="KRH23_003642"
     CDS             6907..7395
                     /locus_tag="KRH23_003642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3841 domain-containing protein"
                     /protein_id="HHS5226906.1"
                     /translation="MKFYTIQTLEFWNNNKNNKYLSNDYSFILEDFDIPYKWMYSQMT
                     NRIYEFDDSMIWVWTKRPDLRCSGYLEKGKKGVLLEIEISEDNVLLSEFDLWHLPLMD
                     ITVELYEDEQIEKKVSWERIFDLELCSKLNEVNIEDLTLQGVTSKVPLSNVKLIKEFV
                     AK"
     gene            7480..7887
                     /locus_tag="KRH23_003643"
     CDS             7480..7887
                     /locus_tag="KRH23_003643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226907.1"
                     /translation="MSKQQTGIKSTLISEILGISYCIGATLVNKYFFKGSSIEYLPII
                     IWVLAMGAQWVYNKKYDDLIDEASKCILSRVNDIVIKVLFFSVAIVSIFLVTLDINVS
                     NLNIGMSLLVILFIQSLLKLILFIYFDRKGIYN"
     gene            7888..8106
                     /locus_tag="KRH23_003644"
     CDS             7888..8106
                     /locus_tag="KRH23_003644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HHS5226908.1"
                     /translation="MSVLLKTKIKSYREKNLMTQGELAKSVGVRRETIVHLENGRYNP
                     SLKLAMDIAKVFDTTVEELFEFIEENNI"
BASE COUNT         3315 a          845 c         1500 g         2769 t
ORIGIN      
        1 cagtaaagta taaaattcta ttactataat aaaagataga actagaagtc tttatgaaag
       61 tgggaaaagt atttatataa ataaatttat atggtttata gtttaatagt aggaaatatc
      121 gtatgagtaa gaatattgta ttttacataa agatttagca atatgacaca ctgttgtcgt
      181 gttctgtagg atatgattaa taaatcagat atgaaaggag agtgagtaat atgccagaat
      241 tactaaaaaa tatgtataat cgtgagtcac tttatgaagt tgcagtagct atccaatcag
      301 tttacaactc atttaaggta gacgagttca taaaatctac aatggatgag acatggaata
      361 acttagaatt aaaagccaga tgtcgaaaga taagtatgag tttaggaatg tatttaccag
      421 aagactataa ggaagctctt tccattcttg aaaaatcagt tacaggtttt tattttgctt
      481 ttttctttcc agattttgtt gaagtttatg ggcaggacga cgtaaattgg gatttatcta
      541 taagtgcatt agaaagaaat actgagtatt ggtcttcaga atttgctgta agagcattta
      601 ttatcaagga tgaagagcgt atgatggcac agatgcgtaa atggtctaag cataagagcg
      661 aacatgtacg aagacttgca agtgaaggtt gtcgtcccca gttgccttgg ggacaagcaa
      721 tatccaaatt taaaaaagac cctacacctg tactgcctat attggagcaa cttaaaacag
      781 atacatcaac gtatgtacaa aagagtgttg ctaataatct aaatgatatc tcaaaaacac
      841 atccagattt agtcataagc attgcaaagg attggtacgg taaaaataaa tccactaact
      901 ggattgtaaa gcatggttgc agaactctgc taaaaaaagg aaatcgtgat gtattagctc
      961 tttttggata tgatgatact acttcaataa atattcagga ttttacttta gaaacaacgt
     1021 ctatttctat tggagagaat ttaacttttt catttaatat tttagcaaaa aaagcgacaa
     1081 aaacaaggct cgagtacgga attgattatg tgaaatctaa tggaaaaagg aataggaaga
     1141 tatttaaaat atcggaggtt tcattaaaag aaaatgagaa aaagtcatat atgaaaaaac
     1201 attcatttgc agatgtaagt gtaaggaaac attatccagg tatccactcg attactatta
     1261 ttattaatgg ggtagaaaaa ggcaaacttg attttgaatt aggtgtataa ttttactaac
     1321 agcataacct atatcagata ctttgctaag cctatatcat atattctaat aaatctatat
     1381 taggtagttt actacttgtt tactaaattt aaatacaaag aaatacaggt gctaatccct
     1441 gcccattaaa ggaatatgag cataacacaa aagtagaact tatcaattct gttacgggta
     1501 tagtagtaaa tccatagaat cacaattaga agatgaagtg taaaaaataa gttagtgttg
     1561 attttagttg ctagtgatat tgaatagtta tacaatagcc atataaatta gaatttgtag
     1621 aggagaaatg taaatggatg tatatagttt ttggaatgac actttggcac aagatgctgt
     1681 taagataaga aaatattttc atgaagatgc ttatattaat tggcatgata caaatgagca
     1741 ttttacttta gaagaattta ttattgcaaa ttgtgagtat cctgataaat ggaatggtaa
     1801 agtagaaagg gtgctagaat ttggaaattt agtaattaca gtgacacatg tttatgcaat
     1861 aaataaacca ctatcatttc atgtcgtttc atttatcagc cttaaagatg ataagattat
     1921 ttctattgat gaatattggg gagaggatga tgatgtgcca cagtggagat tagataaaca
     1981 tattggaaag ccaataaaat agtttttgtt ctgttttata actgaaattt tgataacatt
     2041 tgatattttg atttgtcatt ggtcaacata gtcgttagtg taataattta aaaaagtaga
     2101 atttggagag tgaacactat ggaagaaaaa tacatcttat ctgaccgagg gaaagtatat
     2161 tattggataa aagaaagtaa tagtgtgttt gcaaagaact taattttttt gccaggacta
     2221 acagcaaatc atcatctttt tgatttccag atacagtact tttcaaaaaa tcataatgta
     2281 ttagtatggg acgctcctgc tcatggaaaa tcaagacctt acttagattt ctcatattct
     2341 aacttggtag aagaattgaa agtaatttta gatagacaaa atatgaaaaa ggttgtactt
     2401 atagggcaat cggcaggggg atttgtggca cagtccttta ttgtaaaata tccaaatatg
     2461 gtagaaggat taatgatgat tggaacttgt ccatatggaa ctgactatta tagtaagtca
     2521 gatattttct ggttaaaaca gactgaatgg atgttaaagt tattcccaga taaattgttg
     2581 cgaaacataa tatctaagat gtgtggagct acgtctgaag gcagaaggag tatgctgaaa
     2641 atgttagaag gctacgaaaa aaaagaactg tgtcatctca tgtatctggg atttgctggg
     2701 ttcataccag aaattcaaga cttaaatata cattgtccag tttgtttggt ggttggagat
     2761 aaagacaaga cgggtaaagt gagaaaatat aatgagcagt ggcacaataa gactgggtat
     2821 ccattgcaca ttataaaaaa tgattcacat aatgtaaatg tcgataaacc taatgaacta
     2881 aatcagatta tggatatatt tattaagcaa ttataatata taaaaattac atacccatta
     2941 ggtaaattat gtagtatatg tgtttacaga tggttataga aataaatatg taataaacta
     3001 cttaacactt aaaaagtgga tttgtccaga gtataataca aagcatgata tataaatttt
     3061 taagcgaaat acatcaaaag aaggattaga attagtggag ataaaacagc tattagagat
     3121 tataaataaa tagttttaaa ggtactacga atatagagga aggtaaatca tacgttattc
     3181 aaggattata aatgagtagt ttaaaagtac tatcggatag gagtctccat atttaaacct
     3241 tagtaaaggt agttaaagtg gtagtttaaa aactaaaaaa ttatataaag gaattaggta
     3301 taagaaaatg attgagagta taccagcaaa acaaatttta caaaaagtga aatttgacaa
     3361 tacaagatgg tttggaattg actataatat gaatctctat cgtggctgtt ctcatggatg
     3421 tatatattgt gatagccgta gcacaatata caacatagag aattttgaca aagttagata
     3481 taaagaaaat gtgatagaaa ttttaagtaa agaattgcgt tcaaaaagaa aaaaaggggt
     3541 agtaggcatt ggagctatgt ctgacacata taatcctttt gaaaagcaac tttgtattac
     3601 aaagcaggca ctagatttga tttcagaaaa tcattttgga gtgtctattg ataccaaaag
     3661 tagtttggtg gttagagata taccgatttt gaagaaaatt aaaaaaaata actctgctat
     3721 tgtaaagttg actataacca ctgcaaatga tgaattatca aagaaaatag aaccttatgt
     3781 aaatccaagt tctgtacgat ttgacgcagt gaaagaactt aatgattctg gaattttttg
     3841 tggtatatta ttaactccta tgcttccatt tttgactgat actaaagatg aaatacgagc
     3901 aattgtagaa aaagcacaca aggctaatgc aaaatttatt tattgtatgt atggtgtaac
     3961 aatgcgtagt gatcagcgag agttttttta tgagcattta agagatatat caccaaaatt
     4021 ggtacttaaa tatcagaaaa catatggttt aaactatgta tgtactgtac aaaataaaga
     4081 ttgttgtgag aagttgttaa gagaagaatg tgcacgttat ggtattttga cggatatgaa
     4141 agagattata aaagcgtaca agaggtcgga gtcatatact caaataaaat ttttttaaga
     4201 taggctttgg ataagatata atagtggtga ttgatgtgtt gatattatag ttgattgtta
     4261 gagaggatat tatagatgaa tattagtatt gatattctag gtaattgcta gagctgatat
     4321 tataatttat tattagtatt aatattctag ggaattatca ctatatttta aaaaagtaaa
     4381 aatatatatc aaaatgaact aaataagtac tgtaagaagt ttgctaaatt aaggtttgaa
     4441 taaagtgagg gtggagaact tatggtagaa ataaaaacta tagaaataaa taaaaaaggt
     4501 caaattgacc ttttgatgtt agccgatcca tgtgaagaaa tgattgataa atatctcaat
     4561 aaaggaacta tgtacgcatt gtatgataat aaagaactta cttgtatagc agttgtaaat
     4621 gaaatttcca aagaaatatg tgaattaaaa aacattgcta catatgagca ttttcaaaat
     4681 atgggttatg cctcaaagat gatttatcat cttttagatg tttatagtaa aaaatattca
     4741 tcaatggttg ttggtacatc tgaaagcgga gttccttttt atgagaagtt tggatttgtt
     4801 tattcacata aaattaaaaa cttttttgta gataattatc cagaaccaat ctttgaagga
     4861 gaattacaat gtgttgacat gttgtatcta tcatataact tttagatagg ataatatttt
     4921 taggtagata taattaattc atataattat cggaattata atttataaat tatgtataat
     4981 aagagtataa tttatttaga agctgttata ttgtattata ttcaaataag atatataata
     5041 acttgtttat tttgaatttt ggaggattaa ttatggattc aaataataat actataaaat
     5101 caactgttaa aaagggtatt tcttttggtt cttgtttagc aatgattatt tcttatactg
     5161 catggaaatc tattccatgg gctatttttc atggcttaat gagttggata tatgtacttt
     5221 attattgggt aaagtatgca tagattaaat taataaataa gtatgtaata ttgtaaagtt
     5281 taagaaacaa aatgtaaggg agtgtctcga attgaacttt ttagtttata aggcactctt
     5341 ttttgtatta aataaaatat attttcatta cttaaacaat gaaaaagatg agtatctcta
     5401 ttttaataca tacccttata ttcattcatt tatcaacaat agttttaaaa agaaagctat
     5461 ctaaaatcta ttgtaatcta agtgcttctc tttaaagtct taactttagt aatgatatat
     5521 aagtttataa ggttcttatt tcaataatgc aaattttact tagaagttca gactttggca
     5581 tgaagaaatg ggtaataata aaaaagaggt gttgatatga aagaaaaatt agaagaaaaa
     5641 tctaagatta ttaaaacatc aaaagagtat aagagaactg taattgaaga aaaggacaga
     5701 gaatggacca aaaaattaaa tgacatactt agtagaggtg atttttctaa tgaaaaatta
     5761 gataaaatca aggatttaat tccaaaagaa atattgacta gtgaaaatgt tggagaagtt
     5821 gtaactgaag atgggtatgc taagcctgag tatgatgagg tatttaaatc attgtttact
     5881 ttaaataatg attacgattt acttgcaaat tttataaatg atattctcaa agatgctcca
     5941 tatgccaata ggaatatcaa accgttcact catataaaaa gaataattaa ggctgaaacc
     6001 gacccaacaa ttaattacat tggtgagaaa agacctagac ttgatatttt ggctgaagat
     6061 gaagaaagta atcatataaa tattgagatg caaagagctc ttgaagatga ttatttggaa
     6121 agagctgaat attatcttag tcgtgtacat ggtagaaagt tagaagaagg taaagagtat
     6181 aaagaaattg gaaaaactat tggaatacat atactaaatc atgtaaaata taatcatata
     6241 gaagattatg taaattgcct gagattaaca atggatgggc atccagatat ttattctagt
     6301 aaaactgcat tatattttat agaacttcca aaaattcgta aatccagttg tatagcaaac
     6361 agagttctaa tatggggtaa acttattgat aatccttctc atatcgatat tagaatacta
     6421 tctaaaacgg attatgttat taaaagagca cttgatagat taaaagaatt aggcagtaat
     6481 gaggagtatt tattaaattt aaagagaggt gcgtatatta tgaataaaag tagaaatttt
     6541 aaagaagaaa tttttcaaga aggtgttgaa aaaggtattg caaaaggcat tgcaaaaggg
     6601 aaaagagaag agaaatttaa tatcatcata aaattaaaaa ataaaggata taatttgagt
     6661 gaaatatgtg atattataga tgatttgaat aaatcagagg tggaaaaaat ctataatcaa
     6721 aactaatact ataattgaga tggtactagg taaatacaaa gcttcctctt ttaaatttaa
     6781 attaatataa aaccttgtta tttaactata agtagataca aagagatata taagctaagg
     6841 agatgattca aaataaaagt ttgaaccatc tccttcttat agaaaaacaa agggggtgat
     6901 ttatatatga aattttatac tatacagact ttagaatttt ggaataacaa taaaaacaat
     6961 aaatatctat caaatgatta ttcttttata ttagaagact ttgatattcc atacaaatgg
     7021 atgtatagtc aaatgacaaa tagaatatat gaatttgatg atagtatgat atgggtttgg
     7081 acgaagagac ctgatttaag atgtagtggt tatttagaaa aaggaaaaaa aggcgtttta
     7141 cttgaaatag aaataagtga agacaatgtg ttattatcag aatttgattt atggcattta
     7201 cctttaatgg atattactgt agaactttat gaagatgaac aaattgaaaa gaaggtaagt
     7261 tgggaaagaa tatttgactt agaactgtgt tcaaaattaa atgaagttaa tatagaagat
     7321 ttgacattgc aaggagtgac atctaaagtg cctctatcta atgtaaaatt aataaaagaa
     7381 tttgttgcaa aataatattt ttattgaaat ttattcaaaa aagttatata tttataacaa
     7441 gaggtgttat aaatacataa ctttttaagg ggattttata tgtctaaaca acaaactggt
     7501 attaaatcaa cacttatttc agaaatattg ggaatttctt attgtattgg agctacatta
     7561 gtaaataagt atttttttaa aggaagtagt attgaatatc ttcctataat tatttgggta
     7621 ttagctatgg gagctcagtg ggtctataat aaaaagtatg atgatttaat tgatgaggca
     7681 tcaaagtgta tactatcaag agttaatgat attgtaataa aagtattgtt tttttctgta
     7741 gctatagtat ctatatttct tgtaactttg gacataaatg tgtcaaattt aaatatagga
     7801 atgtctttat tagtcatttt gtttattcaa tccttgttga agttaattct atttatatat
     7861 tttgacagaa aggggatata caattaggtg tcagtattac taaagacaaa aattaaatcc
     7921 tatagagaaa agaaccttat gacacaaggt gaacttgcaa agtcagtagg agtaagacgt
     7981 gaaactattg tacatttaga aaatggtcgc tacaatcctt ctttaaaact ggcaatggat
     8041 attgctaagg tatttgatac aactgtagaa gagttgtttg aatttattga agaaaataat
     8101 atttaaattt catgtattac ttatgcatta gagaatgaat taattatagg taaaaaacca
     8161 agcttataga ttagagaata aatgacttat agatgaaaaa ccaagctcat agattaaaga
     8221 atgaatgatt tatagatgaa aaagaaagct tatagattag agaataaatg acttatagat
     8281 aaagaagcaa gcttatagat tagagaatga attaattata ggtaaaaacc aagcttatag
     8341 attagagaat gaattaatta taggtaaaaa ccaagcttat agattaaaaa atgaatgatt
     8401 tatagatgaa gaactaaact tatagatta
//
LOCUS       DAEORM030000103         8415 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.109, whole genome shotgun sequence.
ACCESSION   DAEORM030000103 DAEORM030000000
VERSION     DAEORM030000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8415)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8415)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 8415)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8415
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.109"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            37..792
                     /locus_tag="KRH23_003645"
     CDS             37..792
                     /locus_tag="KRH23_003645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHS5226909.1"
                     /translation="MLQIKNLSKSFPNPYGEPNTIFENLSIDIEDGEFVSIIGSNGTG
                     KSTLLNIISGLIKESSGQVLLNKHNLSNLAEHRRTQIVSRVFQDPSLGTCPSMTVREN
                     LSLALNKGKLLNLRKCLRYKRDFLENLLEGVSLDLKKYLDVQVKFLSGGQRQSLSLIM
                     SCLTNPSVLLLDEHTAALDPKTSNEVIELTNKIVREKNITTLMVTHNLKHALHYGDRL
                     IMLHKGEVVLDVKGKEKEQLTVEEILEKFEYAV"
     gene            923..1945
                     /locus_tag="KRH23_003646"
     CDS             923..1945
                     /locus_tag="KRH23_003646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CD0873 family tyrosine ABC transporter
                     substrate-binding lipoprotein"
                     /protein_id="HHS5226910.1"
                     /translation="MINKKRLASLILAGALSISMLTGCSQGGDSGNSKQESNSKGKEV
                     KKIGITQLVEHPALDATRTGFVKALEKNGFKDGENIDIDFQNAQNDMPTTQSIASKFA
                     SDKKDLIFAISTPSAQAAFNATKDIPILITAVSDPVAAGLVKTLEKPGTNVSGTSDFV
                     SVDKGLELLKIFAPKAKTIGVMYNTSEVNSKVQVDALKEYASKNGFKVVEKGITTSNE
                     VNQGISSLVGKIDVLYVPTDNLVASSMPIVSKIATENKIPVIAAESGPVEKGALACQG
                     INYEKLGYKTGEMAVKILNGESVSDMPVATSDDTDIIVNEDILKALGMEKPSNENISY
                     VKTKQE"
     gene            complement(2109..2666)
                     /locus_tag="KRH23_003647"
     CDS             complement(2109..2666)
                     /locus_tag="KRH23_003647"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016407 - acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HHS5226911.1"
                     /translation="MTEKEKMLSGKGYYANDELLVKEREYCKKLTRLFNNTLEDEYEK
                     REDILRQLFGSVGKQINVEQNIRCDYGYNIHVGENFFANYDCIFLDVCKIEIGDNVML
                     APNVQIYTAYHPIDAQLRNSGIEYGSPIKIGDNVWIGGGVIITPGITIGDNVVIGAGS
                     VVTKDIPPNTVAVGNPCRVIKKIEE"
     gene            complement(2672..3748)
                     /locus_tag="KRH23_003648"
     CDS             complement(2672..3748)
                     /locus_tag="KRH23_003648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015419 - ABC-type sulfate transporter
                     activity [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate/molybdate ABC transporter ATP-binding
                     protein"
                     /protein_id="HHS5226912.1"
                     /translation="MSLYVDIEKDLSSFKLKVEIKQEKGTLGFLGESGSGKSMTLKCI
                     AGLEKPTRGKIVLNDRVLFDSEKKINLSTQDRKVGFLFQNYALFPHMTVSQNIELGLL
                     KLSKSEKKEIVARYLDILKLNGFEGRYPWQLSGGQQQRVALARALATSPDILLLDEPF
                     SALDHHLRSNMEKELMNMLKDYKGDILFVTHDIEEAYRVCDDIIVYNKGEGLPKRPKK
                     ELFESPKYLIEAKITGCKNISKLNRLDKNTIYATDWGCELTLNREIGDNIEYVGIREH
                     HIKVLDSNEDLNEKLCFELINIVENPFTYTIYVRKTDLSNECVPIQIELEKSKMRFKK
                     GDRIYLDFPQEYLFCFRYNYNKKE"
     gene            complement(3749..4432)
                     /gene="modB"
                     /locus_tag="KRH23_003649"
     CDS             complement(3749..4432)
                     /gene="modB"
                     /locus_tag="KRH23_003649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015412 - ABC-type molybdate transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015689 - molybdate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter permease subunit"
                     /protein_id="HHS5226913.1"
                     /translation="MGTDWSPLWISLKTSILSTIITFVIGIFVSYIMANYRGKWKGLI
                     DGLFTLPLILPPTVVGFFLLLLCGKNGFIGKFLLNFDRTLIFSWTATVISAVVVSFPM
                     MYRTSRSAFEQIDNNMLSAARTLGLNEWKVFFKIAVPLAWPGIIGGLVLSFARALGEF
                     GATLMIAGNIPGKTQTMPIAIFFAVEGGDMNKAMMWVMIIVAISIAMILLLNYWSEFQ
                     QKIIGKRCG"
     gene            complement(4581..5393)
                     /gene="modA"
                     /locus_tag="KRH23_003650"
     CDS             complement(4581..5393)
                     /gene="modA"
                     /locus_tag="KRH23_003650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030288 - outer membrane-bounded
                     periplasmic space [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015412 - ABC-type molybdate transporter
                     activity [Evidence IEA];
                     GO_function: GO:0030973 - molybdate ion binding [Evidence
                     IEA];
                     GO_process: GO:0015689 - molybdate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter substrate-binding
                     protein"
                     /protein_id="HHS5226914.1"
                     /translation="MKKILGILGLVACLTLGTVGCNSNEDKKDDGKQEKTTKSSDSVE
                     LNISAAASLKEAMAKIEEEYKKVDSNVKLTVNYGASGSLQQQIEQGAPCDLFISAGQK
                     QMKALDEEKLLVSDTMKDLVKNDLVLISSADSSVSGMKDLTTDKVKKIAVGEAESVPA
                     GKYADEVLTNLNLKDKLKDKLVFAKDVKEVLAWVQSGNADVGFVYFSDTVNNDKIKVV
                     EKTDEKTHSPITYPVSVIKASKNVDAAKKFEEFLLSESGQKIFEEFGYKKVE"
     gene            5586..6515
                     /locus_tag="KRH23_003651"
     CDS             5586..6515
                     /locus_tag="KRH23_003651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HHS5226915.1"
                     /translation="MDSLSSLTPVEVAELLKITKNTVYELIKRGELPSYKVGKKIRVD
                     TKDVEEYINSQKTGKVKDTHFNNKNIDINNNFKIIISGQDVILDILARSVEKKLDGIS
                     TFRSYIGSYNALYELYNGRVSIASSHLWDFETDEYNSTFVKKLLPGIPCVLINLAYRM
                     QGFYVAKGNPKEITTWDDLTKPSITIVNREKGSGTRVLLDGKLRLLNFNGKHIKGYDN
                     EELSHLGVASTVSRGIADVGLGNEKAALQVNNIDFIPLHKERYDLVIKKEDLQNPVYQ
                     TIINIINSPEFKAELQGLGGYDLTDTGKTIAKV"
     gene            complement(6676..7125)
                     /locus_tag="KRH23_003652"
     CDS             complement(6676..7125)
                     /locus_tag="KRH23_003652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226916.1"
                     /translation="MKNKNNKDKNMLNIKVLRVLGVLLILFDYTGDTLNFYNFFAKPL
                     VSGNLYKTTGTDCIVFLLFIVECVYLVGRYILKVKINWSEIIENEKGNFINNLLVEKI
                     QEESNIVYNLLNSYVLPHIYKKARGLMFKTYHMLIYIKEKYYYVNIY"
     gene            complement(7328..8200)
                     /locus_tag="KRH23_003653"
     CDS             complement(7328..8200)
                     /locus_tag="KRH23_003653"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HHS5226917.1"
                     /translation="MYNSSVGLEQLIKNEDIVKIFSERKDRPLEKLKNYKTSELMIQS
                     SNNYKLESLFITSNIKTRDTMILVHGIGSSYYEMLKVAYRYLDKGYNVLVYNQRNTGN
                     SGGDNYTFGLYERYDLDSLVKFVKNKFPEGRLGVHGFSMGAGTAAMHSEINSKDDKVD
                     FYILDSPYSEMKDAIRMGVLEKRIPDILINYVVTCGDLYNKFKSGFWYSDVKPYESVE
                     KSNVPILFIHGTKDTVCNYQNSKKMYDLVKHDKKDLWLIEGIGHVDGFEHDNTVYFNK
                     IFKFIDSNVLSDKS"
BASE COUNT         2922 a         1383 c         1012 g         3098 t
ORIGIN      
        1 gtaccaaaaa taaatcagaa aaaagaggtg ttgtagatgt tacaaattaa aaatctttca
       61 aagagtttcc ctaatccata tggtgaacct aatactatct ttgaaaattt atcaatcgat
      121 atagaagatg gtgaatttgt aagtatcata ggtagtaatg gaactggtaa atctacttta
      181 ttaaatataa tatccgggct tataaaagaa tcttctggtc aagtattatt aaataaacat
      241 aacttgtcta atttagctga acacagaaga actcaaatag taagtagagt ttttcaagac
      301 ccaagtcttg gaacttgccc ttctatgact gttagagaaa acttgtcttt agctcttaac
      361 aaaggaaaac tattaaatct aagaaaatgt cttcgttaca aaagagattt cttagaaaat
      421 ttattggaag gtgtatctct tgatttaaaa aaataccttg atgttcaagt aaaattttta
      481 tcaggaggtc aaagacaatc attatcacta attatgtcgt gcttaacaaa tccatcagtt
      541 ttattacttg atgaacatac agcagcactt gacccaaaaa catcaaatga agtaattgaa
      601 ttgactaata agattgtaag ggaaaaaaat ataactacac ttatggttac tcacaactta
      661 aaacacgctc ttcattatgg tgatagattg ataatgcttc ataagggtga agttgtatta
      721 gatgtaaaag gtaaagaaaa agaacaatta acagttgaag aaatcttaga aaaatttgaa
      781 tatgcagttt aaaataatat atctattgta ttaaactcgg ctttaaaata aagttaaaat
      841 tacaataatt atggttgctt tgtaataatt catatgaata tatgaacata tataacaata
      901 aatttttgag ggggatataa aaatgattaa taaaaaaaga ttggcaagtt tgattttagc
      961 tggtgctctt agtatatcta tgcttacagg gtgttcacaa ggaggagact ctggtaattc
     1021 aaaacaagaa agtaattcta aaggtaaaga agttaaaaaa attggtataa ctcaactggt
     1081 tgaacatcca gcattagatg ccactaggac aggttttgta aaagcattag aaaagaacgg
     1141 atttaaagat ggagaaaata ttgatataga cttccaaaat gctcaaaatg acatgcctac
     1201 tacacaaagt attgcgagta aatttgcatc tgataagaag gacttaatat ttgctatatc
     1261 tactccatca gctcaggcag catttaatgc tactaaagat atacctatac ttattactgc
     1321 tgtgagtgac cctgttgctg ctggattagt taaaactctt gaaaagccag gcacaaatgt
     1381 atctggaaca tcagattttg tttctgtaga caaaggttta gaacttctta aaatatttgc
     1441 tcctaaggca aaaactatag gagttatgta caatactagt gaagtaaatt ccaaagttca
     1501 agttgatgct ttaaaagaat atgcatctaa aaatggattt aaagttgttg aaaaaggtat
     1561 aactacttca aatgaagtta accaaggtat ttctagttta gttggcaaaa tagacgtatt
     1621 atatgtccct acagataact tagtggcttc ttctatgcct atagtctcta aaatagctac
     1681 tgagaataaa atacctgtta tagcagctga atctggtcca gttgaaaaag gtgctcttgc
     1741 ttgtcaaggt atcaactacg aaaaactagg ttacaaaaca ggtgaaatgg cagttaaaat
     1801 tttaaatggc gaatcagtat ctgatatgcc tgtggctaca tcagatgata cagatatcat
     1861 tgttaatgaa gatatattaa aagctttagg tatggaaaaa ccttctaatg aaaatatttc
     1921 ttatgtaaag actaaacaag aatagaaaga tattttctat atacgattaa tatgcctgtt
     1981 tctataaatt aatttataga aacaggcata tatttttatt ttaatgtatt atctatttaa
     2041 agattatatg taaatgctct taatttgttt gtataaattt tacttgtata aactttatac
     2101 aatcatattt attcttctat tttctttatt actctacatg gatttccaac agctacagta
     2161 tttggtggta tatcttttgt gactacactt cctgcaccta ttactacatt atcacctata
     2221 gtaattcctg gtgttatgat tactccccca cctatccata cattatcacc tatttttata
     2281 ggagaaccat actctatgcc tgaatttcta agttgtgcat caattggatg ataggctgta
     2341 tagatttgaa cgtttggagc taacattaca ttgtcaccta tttcaatttt acatacatct
     2401 aaaaaaatac aatcataatt tgcaaagaaa ttttcgccta catgtatgtt atatccataa
     2461 tcacacctaa tattttgttc tacatttatt tgcttgccaa ctgaaccaaa tagttgtctt
     2521 aaaatatctt ctcttttttc atattcatcc tctaaagtat tattaaacaa tctagttaat
     2581 tttttacaat actctctttc ttttactaac aattcatcat ttgcatagta tcctttccca
     2641 gacaacattt tttctttttc agtcatatag tttactcctt tttgttataa ttgtatctaa
     2701 agcaaaataa atattcctgt ggaaaatcta aatatattct gtcacctttc ttaaatctca
     2761 ttttactttt ttccaattct atttgaatag gtacacattc gttagataaa tcagtttttc
     2821 taacatatat agtatatgta aaaggatttt ctacaatgtt aatcaattcg aaacataact
     2881 tttcatttaa atcttcatta gaatccaaga ccttaatatg atgctccctg attcccacat
     2941 attctatatt atcacctatt tctctattta atgtcaactc gcatccccag tctgtagcat
     3001 aaatagtatt tttatccagt ctatttaatt tggatatatt tttacaccct gttatcttag
     3061 cttctataag gtactttgga gattcaaaga gctctttttt aggtctcttt ggaagacctt
     3121 ctcctttgtt gtacactata atatcatcac aaactcggta agcttcttca atatcatgag
     3181 taacaaatag tatatctccc ttgtaatctt ttaacatatt cataagttct ttttccatat
     3241 tgcttcttaa atgatggtcc aatgctgaga aaggttcatc taaaagtaat atatctggag
     3301 atgttgccaa tgctctagct agtgctaccc tttgttgttg accaccagat aattgccaag
     3361 ggtatctccc ctcaaaccca tttaatttaa gtatatctaa gtaccttgct actatttcct
     3421 ttttttcact cttacttagt tttaaaagcc caagttctat attttgactt acagtcatat
     3481 gtggaaacaa agcatagttt tgaaataaaa atcctacctt tctatcttgt gttgataaat
     3541 ttatcttctt ttcagaatca aatagaactc tatcatttaa tacaatttta cctcttgttg
     3601 gtttctcaag ccctgctata cattttaatg tcatactttt tccagaacca gattctccca
     3661 aaaaccccag agtacctttt tcttgtttaa tttctacctt tagtttaaaa gaggataaat
     3721 ctttttcaat atccacgtat aagctcaact atccacacct ctttcctata attttctgct
     3781 gaaattccga ccaataattt agtaataaaa tcattgctat agatattgct acaataatca
     3841 taacccacat catagcttta ttcatatctc cgccttcaac agcaaaaaat atagctattg
     3901 gcatagtttg agtttttcca ggtatatttc cagctatcat aagtgtagca ccaaattctc
     3961 caagagctct ggcaaacgac agcaccaatc caccaattat tccaggccat gctaatggaa
     4021 ctgcaatctt aaaaaatact ttccattcat taagacctaa tgttctagca gctgacaaca
     4081 tattattatc aatctgttca aaagctgacc ttgaagttct atacatcata ggaaaagaca
     4141 ccactactgc tgaaattaca gttgctgtcc aactaaatat taaagtccta tcgaaattta
     4201 ataaaaactt tcctataaat ccattcttcc cacatagtaa taataaaaag aaacctacaa
     4261 ctgttggtgg caaaattagt ggaagtgtaa atagtccatc tataagaccc ttccacttac
     4321 ctctatagtt agccataata tatgacacaa atattcctat tacaaaagtt attattgttg
     4381 acaaaataga tgtcttaagt gatatccata agggtgacca atctgttccc atctttccct
     4441 ccttaatttt aaatggaaat agtgaaacta ataactctat taatttcact atttccattt
     4501 tattataata cacaattatt ttcaattttc atttatttat atataattta tacttaatta
     4561 cacataattt atttctaagt ttattctact tttttatatc caaattcttc aaaaatcttt
     4621 tgtcctgact cacttaataa aaattcttca aatttcttag cagcatctac gtttttacta
     4681 gctttaatta ctgaaactgg atatgtaata ggcgaatgag ttttttcgtc tgttttttca
     4741 actactttta tcttatcatt attgacagta tcactgaagt aaacgaatcc aacatcagca
     4801 tttcctgatt gcacccatgc taaaacttct tttacatctt ttgcaaatac tagcttatct
     4861 tttaacttat cttttaaatt taaattagtt aacacctcat ctgcatactt accagctgga
     4921 acactttcag cttcaccaac agcaattttc ttcactttat ctgtagtcaa atctttcata
     4981 cctgatacac tactgtcagc agaagaaata agaactaaat cattttttac taaatctttc
     5041 atagtatcag aaactaataa cttctcttca tccaaagctt tcatttgttt ttgacctgct
     5101 gaaataaata aatcacaagg tgctccttgt tctatttgtt gttgtaatga gcctgatgct
     5161 ccatagttaa ctgtaagttt tacatttgaa tcaacttttt tatattcttc ttcaatcttt
     5221 gccattgctt cttttaaact tgcagcagcc gatatattta actctactga atcactactt
     5281 ttagttgttt tttcttgttt tccatcatct tttttgtctt cattactatt gcacccaact
     5341 gtccccaaag ttaaacatgc aactaatcct aatattccca atattttttt cataacaatc
     5401 tccctttttg taaatttgat acacatttta acatgtttta ttatgtttta tcatgttttg
     5461 ttatatatag tttaattata tatacatgat aataaatttt caagtaattt atttacacta
     5521 cttttaaata ttttgctaca ttttcctttt tttaatgtta aaataacctt atatggaggt
     5581 ggattatgga ctcattatca tctttgacac ctgtcgaggt agctgaatta ttaaagataa
     5641 caaaaaatac tgtatatgaa ttaatcaaaa gaggtgaact tccttcttat aaagtaggga
     5701 aaaaaataag agttgatact aaagatgttg aagaatatat caacagccaa aaaactggta
     5761 aagtaaagga tacacatttc aacaataaaa atatagatat aaataataat ttcaaaatta
     5821 ttatttctgg tcaagatgta atattagaca ttttagctag gtctgttgaa aaaaaattgg
     5881 atggaataag tacatttcgc tcttatatag gtagttataa tgctttgtat gagttatata
     5941 atggcagagt ttctatagca tcatcccatc tatgggattt cgaaacggat gaatataata
     6001 gcacttttgt taaaaagcta ttgccaggaa taccatgtgt acttataaat ctagcttata
     6061 gaatgcaagg tttctatgtt gctaaaggaa atcctaaaga gataacaacc tgggatgatt
     6121 taacaaaacc aagtataacc attgtaaata gggaaaaagg ttctggaact agggttttac
     6181 tagatggtaa acttagactt ctaaacttta atggtaaaca tataaaaggt tatgataatg
     6241 aagaattatc acatcttgga gttgcaagta ctgtttctcg tggaatagca gatgttggtt
     6301 tgggaaatga aaaagctgct ttacaagtaa ataatatcga ctttattcct cttcacaaag
     6361 agcgctatga tttagttatt aaaaaagaag acttacaaaa tccagtttac caaactataa
     6421 ttaacataat aaactctcct gagtttaaag ctgaacttca aggtcttggc ggatatgatt
     6481 taactgatac tggaaaaact atagcaaaag tttaagatta aaatcgcaat ctattttata
     6541 agacttataa tttttcacaa aatttataac ttaaacacga aataaattgc gattttagtg
     6601 tctcaaaaaa tttatgtctt tcattttatc atccaataca aaatataata taattaattg
     6661 tgcaatcata ttatattaat atatatttac ataatagtat ttttctttaa tgtagattaa
     6721 catatgatat gttttaaaca tcaatcccct tgctttctta tatatatgtg gcaacacata
     6781 tgagtttaat aaattatata caatgttgct ttcttcttgt attttttcaa ccaacaagtt
     6841 atttataaaa ttacctttct cattttcaat aatctcactc caatttatct taacttttaa
     6901 tatatatctt cccactaggt atacacactc tacaataaat aataaaaata caatgcagtc
     6961 agtacctgtt gtcttatata aattacccga tactaatggc tttgcgaaga aattataaaa
     7021 attcaaagta tcacccgtat aatcaaaaag tattaatagc actcctagaa ctctcaatac
     7081 tttaatattc aacatgtttt tatctttatt atttttgttt ttcatatata ctacctctct
     7141 tttctttaga tttgattgta atctaatact aactctttta tttgaggtat aaatgaattt
     7201 aattggtagt tattttcatt tttactagaa attaattcac attactaaac aaaacatata
     7261 tttaaacata aaaatagcct atctatcttt taataaatac aaaaataaat aagctactaa
     7321 tattcaatta acttttatca cttaaaacat tactatctat aaatttaaat attttattga
     7381 agtatactgt attatcatgt tcaaatccat caacatgacc aataccttct ataagccata
     7441 ggtctttttt atcatgttta actaaatcat acattttctt gctattttga taattacaaa
     7501 cagtatcttt tgttccatgt ataaacagta tgggtacatt agatttctca accgactcat
     7561 atggttttac atcactgtac caaaatccag atttaaactt attatataaa tctccacaag
     7621 tcaccacata attgattaat atatctggta ttcgtttttc tagtactccc attctaattg
     7681 catctttcat ttcagaataa ggagaatcca gtatataaaa atcgacctta tcatcttttg
     7741 aatttatctc tgaatgcata gcagctgtcc ctgcccccat ggaaaatcca tgcactccta
     7801 atcttccttc aggaaattta ttttttacaa atttaactag actatctaaa tcataccttt
     7861 cataaagacc aaatgtgtaa ttatctccac cactattacc agtatttctt tgattataaa
     7921 ctaatacatt ataaccttta tctaaatatc tatatgctac ctttaacatt tcatagtaac
     7981 tacttccaat tccatgaaca agtatcatag tatctcttgt ctttatattt gaagttataa
     8041 aaagactttc aagcttgtaa ttattagaac tttgtatcat taattcagat gtcttgtagt
     8101 tttttaattt ctccagcggt ctatcttttc tctctgaaaa tatttttact atatcttcgt
     8161 tttttattaa ctgctctaaa ccaaccgaac tattatacac taatttgcca aatatataag
     8221 atacaattaa taggattaat agaaacacaa ttgatataat tataaattta tttcttaaac
     8281 taatacaatt tttaaaacta tttttcatat ttatttacca tacaattttc ctatattata
     8341 ttttctaagt aatagcataa ttgattatac tattcttata atttctatta tacctactta
     8401 tttattaaaa ataca
//
LOCUS       DAEORM030000104         7821 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.110, whole genome shotgun sequence.
ACCESSION   DAEORM030000104 DAEORM030000000
VERSION     DAEORM030000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7821)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7821)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 7821)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7821
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.110"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            74..1132
                     /locus_tag="KRH23_003654"
     CDS             74..1132
                     /locus_tag="KRH23_003654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium channel family protein"
                     /protein_id="HHS5226918.1"
                     /translation="MNCKWISKIDERKKCHREADSSGYCIFHKENKSDEEIQLMMDTL
                     HKEEISEFNGFVFENEFNAEEILTYNYKILDFSESIFKQKANFKKYIFKKNIIFNYTE
                     FRDKVLFNGCVFLENCDFNRTIFSKHYINDRIFEKVKFKGPDLVVNKVENFPRMDGII
                     FSMCTKFVLKNVEYGKSEYEHGKINYRIARNQATKIGEYEMIGFYYYKERIYSSKIMK
                     CSNYPTFSDYLVEKFFDQIARYTTGYGEKPWNILLVIIAIISVFALLYLFVGIESSNS
                     TLVALDINNIGDYSLSEIFKMYMDLWYFSMATFSTVGYGDMVATSLIGKALAGIEVFF
                     GVTIGAIWASVIIKRMIR"
     gene            1236..2420
                     /locus_tag="KRH23_003655"
     CDS             1236..2420
                     /locus_tag="KRH23_003655"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase family
                     protein"
                     /protein_id="HHS5226919.1"
                     /translation="MKNALKKIISLAMILVFIIPNYSYADDKSVDKYSKTSILIDQET
                     GRVLYSKEPDMKVPLASLSKMMTFLLAIEAIENKEVKETDKVKIDKSIASVKGSSYKL
                     KDGEEVPLIELMRGLMIVSGNDAAIAIAKHICKTKEAFVDRMNKKAKEIGMSNTHFLN
                     PNGLPIYDLSNPKKPAKENISTAKDIAILGKYMFDHYEKQVTAITDMETYTNSDRSFE
                     KSNTNALLRIIPEVDGIKTGYTGNAGYCLSFSMVVNKNDKNEKKRRVIGVVLGTNHKN
                     KRTSASLALLKYGKENFNMKKVIDKDSFIGKKYIKGMKELEVTLKAKDELYTILKDDE
                     SIKSEVKIKNIEYPVKKGDTMGIIKYYTNSGDLLGSVDIVSNNSIDNVSLKTKLKMKF
                     AN"
     gene            2627..3340
                     /gene="rpsB"
                     /locus_tag="KRH23_003656"
     CDS             2627..3340
                     /gene="rpsB"
                     /locus_tag="KRH23_003656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HHS5226920.1"
                     /translation="MSVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIYIIDLQ
                     KTVKKVEEAYKFTKEVAETGKPILFVGTKKQAQDAIKDEAERCGMYFVNERWLGGMLT
                     NHKTIKTRINKLRELEKMEEEGVFNVLPKKEVIKLRAEKEKLEKYLGGIKDMPELPGA
                     MFVVDPRKENIAIQEAHRLGIPVVGIVDTNCDPEQLDFAIPGNDDAIRAVKLITGAMA
                     TAVIEGRQGAEEEVAEDQE"
     gene            3419..4330
                     /gene="tsf"
                     /locus_tag="KRH23_003657"
     CDS             3419..4330
                     /gene="tsf"
                     /locus_tag="KRH23_003657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation elongation factor Ts"
                     /protein_id="HHS5226921.1"
                     /translation="MANITAQMVKELRESTGAGMMDCKKALQEAEGNMEKAVDLLREK
                     GLSKAAKKAGRVAAEGLVAIEMNDDNTVASMVEVNSETDFVAKNEDFKVFVKDAACMA
                     LATDKEDIASLLGETHKEGITLQEVLNNRVAKIGEKLDFRRFAKVVTNGQVAGYIHGG
                     GKIGVLVEMETEARDAKVLELGKDVAMQVAAMNPKYVSRDEVDAEYIAHETEVLTQQA
                     LNEGKPANIVEKMVKGRLEKELKEVCLLEQTFVKNPDITVKQLVADVAKAVGSDIKVV
                     KVVRFEVGEGIQKREENFAEEVAKQLK"
     gene            4415..5119
                     /gene="pyrH"
                     /locus_tag="KRH23_003658"
     CDS             4415..5119
                     /gene="pyrH"
                     /locus_tag="KRH23_003658"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0033862 - UMP kinase activity [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HHS5226922.1"
                     /translation="MDKPMYKRVLLKLSGEALAGERGFGINNDVVNDIAIAIKKIQEI
                     GVEVAVVVGGGNFWRGRTSEGMDRTTADYIGMLATVMNAMALQDALENIDVATRVQTA
                     IDMRQIAEPYIRRRAVRHLEKERVVIFGAGTGNPYFTTDTTAALRAAEMEAEVILLAK
                     NVDAVYDKDPKVHADAKKFTELSYMEVIQKELKVMDSTATSLCMDNKIPIKVFELTTE
                     NIIRAVKGENIGTTVK"
     gene            5145..5702
                     /gene="frr"
                     /locus_tag="KRH23_003659"
     CDS             5145..5702
                     /gene="frr"
                     /locus_tag="KRH23_003659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008135 - translation factor activity, RNA
                     binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HHS5226923.1"
                     /translation="MKLEIHKQLEEKMNGTIDALKFEFGTIRAGRANAQMLDKIRVDY
                     YGTPTPINQIGAISVPEPRILMISPWDKSAMHEIEKAIANSDLGLNPSNDGEVIRLSV
                     PALTEERRKELAKKASKAAEEFKVRIRNERRDANEKIKKMEKGGELTEDELKKAQDEV
                     QKMTDKFIKEIDTLLSKKEKDIMEV"
     gene            5705..5908
                     /locus_tag="KRH23_003660"
     CDS             5705..5908
                     /locus_tag="KRH23_003660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226924.1"
                     /translation="MKKYYNLLGLHVDEVKQYFDEQNINYTVKSIEGKKDKEKLVVPR
                     VIKISEIGDSVELIITYFSDSLV"
     gene            5937..6671
                     /locus_tag="KRH23_003661"
     CDS             5937..6671
                     /locus_tag="KRH23_003661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HHS5226925.1"
                     /translation="MNNNIIYDIDLNNIPTHIAIIMDGNGRWAKARFLPRTAGHKAGV
                     ETIRDIVKECSKLGVKHLTLYAFSTENWKRPKLEVDTLMNLLSTYLRNEIAELHQNNV
                     KVTAIGDISALPKTCIRELNSAKELTKNNTGVNLNLALNYGSRADIKNALIDIVKNCE
                     SGKIDINNIDEDIIKNYLSTKSIPDPDLVIRTSGEQRLSNFLLWEVAYSEFYFTDIHW
                     PDFKKEELQKAIYVYQRRDRRFGGLK"
     gene            6684..7463
                     /locus_tag="KRH23_003662"
     CDS             6684..7463
                     /locus_tag="KRH23_003662"
                     /EC_number="2.7.7.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004605 - phosphatidate
                     cytidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0016024 - CDP-diacylglycerol biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HHS5226926.1"
                     /translation="MLTRIIASLALVPLFLFVVYGGIPLYIAETAIVYIALHEFYKAF
                     KIKDVHPIFIIGYLFSIYLAVKNIFNLPLEYTYAVIFILFLASIIYMLMGKNNVIDVS
                     ITFLGVFYIGVFLDFIIITINGFEKGSIYVWLIFVISFMTDIFAYFSGYLLGKHKLIP
                     KVSPKKTIEGAIGGIIGSTLCCILFGYLFGIDLLQLAIIGSIGSVIAQLGDLFASSIK
                     RYVGIKDYGKIIPGHGGILDRFDSVILVAPFVYSAIKFFIR"
BASE COUNT         3225 a          791 c         1463 g         2342 t
ORIGIN      
        1 gtatataaaa taaaataata tccaaactaa tacaaaatag taataattgt tttgtactgg
       61 aggatatata tttatgaatt gtaaatggat atctaaaata gatgagagaa aaaaatgtca
      121 tagagaagca gattcttctg gatattgtat ctttcataaa gaaaataagt ctgatgaaga
      181 gatacagttg atgatggata ctcttcataa agaagagata agtgaattta atggatttgt
      241 ttttgaaaat gaatttaatg cggaagaaat attaacttac aattataaaa tactggattt
      301 ttctgaatcc atatttaaac aaaaagcaaa ttttaaaaaa tatattttta aaaagaatat
      361 tatttttaac tatacagaat ttagagataa agttttattt aatggttgtg tattcttaga
      421 aaactgtgat tttaatagaa ccatatttag taaacactat ataaatgacc gtatatttga
      481 aaaagtgaaa tttaaaggac ctgatttggt agttaataaa gtagaaaatt ttccacgaat
      541 ggatggaata atttttagca tgtgtacaaa atttgtgtta aagaatgttg aatatggaaa
      601 aagtgagtat gagcatggca agataaatta tagaatagct agaaatcaag caacaaaaat
      661 tggagaatat gagatgatag gattttacta ttataaggaa agaatttata gtagtaaaat
      721 aatgaaatgt tctaattatc ctactttcag tgattattta gttgaaaaat tttttgacca
      781 aatagcacgt tacacaacag gttatggaga aaagccatgg aatatattat tagttattat
      841 agcaataata agtgtttttg ctttattata cttatttgta ggcatagaaa gttcaaatag
      901 cacacttgta gctttagata taaataatat aggtgattac tcactaagtg agattttcaa
      961 aatgtatatg gatttatggt attttagcat ggctacattt agtacagtag gatatggaga
     1021 tatggttgct acaagtttga ttgggaaagc attggcaggt atagaagtat tttttggagt
     1081 tacaatagga gcaatttggg catctgtgat tattaaaaga atgataaggt aatatttgtg
     1141 taaatatgga taggtattaa ttactagata taaattggac taaataggga aaatttaaat
     1201 ataaatatac ttaataatcc aagaaggtga aaaatttgaa aaatgcacta aaaaaaatta
     1261 tatcattagc catgattcta gtttttataa taccaaatta ttcatatgca gatgataaat
     1321 ctgtagacaa gtattcaaaa acatctatac ttatagacca agaaacaggt agagttttat
     1381 atagtaaaga acctgatatg aaggtaccat tagctagttt aagtaagatg atgacttttt
     1441 tacttgcaat agaagctatt gaaaataaag aagtaaaaga aactgataaa gtaaaaatag
     1501 acaaatctat tgcatcagta aaagggtcaa gttataaact taaagatggt gaagaagtgc
     1561 cacttataga gcttatgaga ggtcttatga ttgtatcagg aaatgatgcg gcaattgcta
     1621 tagcaaaaca tatttgtaaa acgaaagaag catttgtaga tagaatgaat aaaaaagcaa
     1681 aagaaatagg aatgagtaat acacattttc taaatccaaa tggtcttcca atatacgatt
     1741 taagcaaccc caaaaaacca gcaaaagaaa atatctctac tgcaaaagat atagctattc
     1801 ttggaaaata catgtttgac cattatgaaa aacaagtaac agctataact gatatggaga
     1861 catatacaaa ttcagataga agttttgaaa aaagcaatac aaatgcatta ttaagaatta
     1921 taccagaagt agatggtata aaaactggat atactggcaa tgctggatat tgcttatcat
     1981 tttctatggt tgtaaataaa aatgataaaa atgagaaaaa acgtagagta ataggggttg
     2041 tattaggtac taaccataaa aataaaagaa cctctgcttc attagctcta ctgaaatatg
     2101 gaaaagaaaa tttcaatatg aaaaaagtaa ttgataaaga tagctttatt ggtaagaaat
     2161 atataaaagg aatgaaagag ttagaggtta cattaaaagc aaaagatgaa ctttatacaa
     2221 tattaaaaga tgatgaaagt ataaaatcag aagttaagat taaaaatata gagtaccctg
     2281 ttaaaaaagg tgatactatg ggtattataa aatattatac taattcaggt gacttacttg
     2341 gaagtgtaga tatagtaagt aataatagta tagataacgt atcattaaaa acaaaattaa
     2401 aaatgaaatt tgcaaattaa attcaaaaaa tggtataaaa tacacaaaaa aatataaaaa
     2461 tagaaaatat ggaaaaaata ttgttatttc ttcacctctg tgatatacta ctagaggtga
     2521 aaaaataaaa taaatcacac acagcattgg gatccttaaa aggtgcctat tacatggttt
     2581 tttagggaga agatcaagct ggaggtataa aaccaggagg taagatatgt cagtaatatc
     2641 aatgaaacaa ttattagaag caggtgttca ctttggtcac caaacaagaa gatggaaccc
     2701 taaaatggct aagtatatat tcacagagag aaatggaata tatataatcg acttacaaaa
     2761 aacagttaaa aaagttgaag aagcttacaa gttcactaaa gaagtagctg aaacaggaaa
     2821 gccaatctta ttcgtaggaa ctaaaaaaca agctcaagat gcgataaaag atgaagctga
     2881 aagatgtgga atgtactttg ttaatgaaag atggttaggt ggaatgttaa caaaccacaa
     2941 aactataaaa acaagaataa ataaattaag agaattagaa aaaatggaag aagaaggcgt
     3001 atttaatgtt cttcctaaaa aagaagttat aaaattaaga gctgaaaaag aaaaactaga
     3061 aaaatactta ggtggaataa aagacatgcc tgaattacca ggtgcaatgt tcgtagttga
     3121 cccaagaaaa gaaaacatag ctattcaaga agctcataga ttaggtatac cagtagttgg
     3181 tatagttgat actaactgtg acccagaaca attagacttt gctataccag gaaatgatga
     3241 cgctataaga gccgtaaaat taataactgg tgctatggca acagctgtaa ttgaaggtag
     3301 acaaggtgct gaggaagaag tagctgaaga ccaagaataa taatttgaca attaaatggt
     3361 aagggtcgcc cttaccattt ataatatgga atagaataag taggaggaaa cttaaaaaat
     3421 ggctaatata actgctcaaa tggtaaaaga gttaagagaa agtacaggcg caggaatgat
     3481 ggactgcaag aaagctttac aagaagctga aggaaacatg gaaaaagcag tagatttatt
     3541 aagagaaaaa ggattatcaa aagctgctaa aaaagctggt agagttgctg ctgaaggtct
     3601 agttgcaata gaaatgaatg atgataatac agttgcttct atggtagaag ttaactcaga
     3661 gacagatttc gttgctaaaa acgaagactt caaagtgttc gttaaagatg ctgcttgtat
     3721 ggcattagct actgataaag aagatatagc ttctttatta ggtgaaactc ataaagaggg
     3781 aataacttta caagaagttt taaataatag agttgcaaaa ataggtgaga aattagactt
     3841 tagaagattt gctaaagttg taactaatgg acaagttgct ggatacattc acggtggtgg
     3901 aaaaataggt gttcttgttg aaatggaaac agaagctaga gatgctaaag ttttagaatt
     3961 aggtaaagat gtagctatgc aagttgctgc tatgaatcct aagtatgttt caagagatga
     4021 agtagatgct gaatacatag cacatgaaac agaagtatta actcaacaag ctttaaatga
     4081 aggaaaacca gctaatatag ttgaaaaaat ggttaaagga agattagaaa aagaattaaa
     4141 agaggtttgt ttattagagc aaactttcgt taaaaatcca gatataactg ttaaacaatt
     4201 agttgctgat gttgctaagg cagtaggttc tgatataaaa gttgttaaag ttgtgagatt
     4261 cgaagttggt gaaggtatac aaaagagaga agaaaacttt gcagaagaag ttgctaagca
     4321 acttaagtaa taaccaaaga gagaacacgc aggtgttctc ttttttaaaa aatagaaaaa
     4381 attggatatg aaggattgaa ataggaggtt tctgatggat aaaccaatgt acaaaagggt
     4441 attgttaaaa ttaagtggag aagcattagc aggagaaaga ggttttggta taaataatga
     4501 tgtagttaat gatattgcta ttgctataaa aaaaatacaa gaaataggtg ttgaagtagc
     4561 tgtagtagta ggtggaggaa acttctggag aggcagaacc agtgaaggaa tggacagaac
     4621 tactgctgac tatataggaa tgttagctac agttatgaat gcaatggcgc tacaggatgc
     4681 actagaaaat atagatgttg ctacaagagt tcaaactgct atagacatga gacaaattgc
     4741 agaaccatat ataagaagaa gagcagttag acacttagaa aaggaaagag ttgttatatt
     4801 tggtgcagga acaggaaacc cttactttac aacagataca actgctgctt tacgtgctgc
     4861 tgagatggaa gcagaagtta tattgttagc taaaaatgtt gatgcagtat atgacaagga
     4921 tccaaaagta catgcagatg ctaagaaatt tacagaatta agttacatgg aagttataca
     4981 gaaagaatta aaagtaatgg attctacagc tacatcttta tgtatggata ataaaattcc
     5041 aataaaggta tttgagctta caacagagaa tataataaga gcagtaaaag gcgaaaatat
     5101 aggaactact gtaaaataat gaagaatgaa ggaggagtaa aattatgaaa ctggaaatac
     5161 ataagcaatt agaagagaaa atgaatggga caattgatgc tttaaagttt gaatttggaa
     5221 ctataagagc aggaagagct aatgcacaaa tgctagacaa aataagagtt gattattatg
     5281 gaactccaac tccaataaat caaataggtg ctatatctgt accagaacca agaatattaa
     5341 tgatatctcc ttgggataaa tctgctatgc atgaaataga aaaagcaata gctaactcag
     5401 acttaggatt aaatccatca aatgatggtg aggttataag actttctgta cctgctttaa
     5461 cagaagaaag aagaaaagaa ttagctaaaa aagctagtaa agctgcagaa gaatttaaag
     5521 ttagaataag aaatgaaaga agagacgcca atgagaagat taaaaagatg gaaaaaggcg
     5581 gagaattaac tgaagatgaa ttaaaaaaag cacaagatga agttcaaaaa atgactgata
     5641 aatttataaa agaaatagat acattattat ctaaaaaaga aaaggatata atggaggtat
     5701 aatattgaaa aaatattata accttttagg tcttcatgta gatgaggtaa aacaatattt
     5761 tgatgagcaa aatataaatt ataccgtaaa atctattgaa ggtaaaaagg ataaagaaaa
     5821 acttgtagtt cctagagtta taaaaatatc tgagataggt gatagtgtag aactgataat
     5881 cacatacttt tctgactcct tagtttaagg agtcagaaca atattggagg caaaatatga
     5941 ataacaacat tatatatgat atagacttaa ataacatacc tactcatatt gctattataa
     6001 tggatggaaa tggaagatgg gcaaaagcta gatttcttcc aagaactgca ggacataagg
     6061 ctggagtaga aactataaga gatatagtaa aagaatgctc aaaattaggt gttaagcact
     6121 taacattata tgcattttca acagaaaact ggaaaagacc gaaacttgaa gttgacacac
     6181 ttatgaactt attatctaca tacttaagaa atgaaatagc tgaacttcac caaaacaatg
     6241 taaaagtaac tgctatagga gatataagtg ctttaccaaa aacttgtata agagaattaa
     6301 actcagctaa ggaactgaca aaaaacaata caggagttaa cttaaattta gcattaaact
     6361 acggaagtag agcagatata aaaaatgctc ttatagatat agtaaaaaat tgtgaaagtg
     6421 gtaaaataga tataaacaat attgatgaag atattataaa aaactattta agcacaaagt
     6481 ctataccaga tccagacttg gtaataagaa caagtggtga acaaagattg agtaactttt
     6541 tactttggga agttgcttat tctgagtttt actttactga tatacattgg cctgatttta
     6601 aaaaagaaga actacagaag gctatatacg tatatcaaag aagggataga agatttggag
     6661 gacttaagta aggagattat tttatgctta caagaattat tgcttcacta gctctggttc
     6721 cattatttct atttgttgta tatggaggta ttcctctata tatagctgag acagcaatag
     6781 tttatattgc attgcatgag ttttataagg catttaaaat aaaagatgta catccaatat
     6841 tcattatagg atatttattt tctatttatt tagctgtaaa aaatattttt aatttaccat
     6901 tagaatatac ttatgcagta atttttattt tatttttagc aagtataatt tatatgttga
     6961 tgggcaaaaa caatgttata gatgtttcga ttacgttttt aggagttttt tatataggag
     7021 tatttttaga ttttataatt ataactataa atggatttga aaaaggtagt atatatgtat
     7081 ggcttatatt tgtgatatct tttatgacag atatatttgc atattttagt ggttatttac
     7141 ttggaaaaca taagctaatt cctaaagtta gtcctaaaaa gactatagaa ggagctattg
     7201 gaggaataat aggaagtaca ctttgttgta ttttatttgg atatttattt ggcattgatt
     7261 tgcttcaatt agcgataata ggaagtatag gaagtgtaat agctcaatta ggagatttat
     7321 ttgcatcttc tataaagaga tatgtaggga taaaggatta tggaaagata atacctggtc
     7381 atgggggtat attagataga tttgatagtg ttatattagt tgcacctttt gtatatagtg
     7441 cgattaaatt ttttattaga taaagattgg ttggatttaa aagagcaatc tataattgct
     7501 agtaatgaaa atagctatgt aacttttaaa tgcagagata ttctgcagtt attagttaca
     7561 tggctatttt cattgttcaa aaatttagaa gaccttgggg aattgtataa gaataggtat
     7621 tactttataa tagtatacta tatttgtagt gagtatattt tttatactat aactatcatt
     7681 aaaaaatatt tttttgttta ataatttcga tatttttagc tttattatat atttataata
     7741 tatatgtata aatgtaacta atttattatc catttataaa ttttattttt aaatataatt
     7801 aataagaaat aagtaaatta t
//
LOCUS       DAEORM030000105         7719 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.111, whole genome shotgun sequence.
ACCESSION   DAEORM030000105 DAEORM030000000
VERSION     DAEORM030000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7719)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7719)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 7719)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7719
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.111"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            complement(216..1034)
                     /locus_tag="KRH23_003663"
     CDS             complement(216..1034)
                     /locus_tag="KRH23_003663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HHS5226927.1"
                     /translation="MFKIGDFSKLSKISIRMLRHYDEIGLLTPSHTNKTNGYRYYSAD
                     QLSTTNRIHALKDMGFGLYSIKEILTEYNDKESLIKYLNIHHSQVKEQLEDTQKKLLK
                     IETTIKRIGGNDIMKNYDVTIKNFAPKYMMTLRRVIPTYQDEGMLWHQAFLETKDQNV
                     QIEPPKYSKAVFYDTGYKEDYVDVEVQVAVSGKYKDTEHVKFKTVPSVTAATAIVNGN
                     FNQVADACEAIGNWISDNNYEVDGPMFNIYHVSPGNDSNPDNWVTEVCFPVKKK"
     gene            1202..1783
                     /locus_tag="KRH23_003664"
     CDS             1202..1783
                     /locus_tag="KRH23_003664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HHS5226928.1"
                     /translation="MKSNDKDARERIIEVTLNLLNEVDDIEEITVRKIAERANVGVGL
                     INYHFKTKDNLLSTAIGDVMSNIIAELYDDSVYTLRPIEDLKNLLKKLCDTGLHYEKV
                     LPFVLNQCITNGDMQAELDIVPMLRKIFGNKKDEMSLRIIALQIILPIQISALSTESF
                     QLYSGINIKNKYERDKFIDILIENIIGEDVDVR"
     gene            1780..1974
                     /locus_tag="KRH23_003665"
     CDS             1780..1974
                     /locus_tag="KRH23_003665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226929.1"
                     /translation="MKIITIGSSLITVLLFLSTMVCGFWIKNNKVTDASSIKFHMNSA
                     IFTGIFLLISTIFLIIYIKK"
     gene            complement(2138..3880)
                     /locus_tag="KRH23_003666"
     CDS             complement(2138..3880)
                     /locus_tag="KRH23_003666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M3"
                     /protein_id="HHS5226930.1"
                     /translation="MVKSKKKIFVFLILIAVFIIFASYIRNYTNDTKKDSVRGTIPFE
                     KMEYKRPNIQSICENINKCNDKLLTAKTAKEQLNLFNEVDKIYQDFYSTLTIAKIRNN
                     IDSSDEFYSKEYKYLMSKSVDVDMSYKDFQDRFVTSKFSKELEKELGKDTFNYLKNIG
                     KLNSKEVEGLLKKEQDLVVKYEDLLAKSTVSIDGIEVDFEEALSRPNLSPEEYVKIYS
                     DYLKKYNPIFGNIFLELIQTRTEIASKQGFKNYIDYAYMNLNKDYSQEEAKKFRQDVK
                     DYIVPLYREISSKPSDSSIYIKVYKNRSFRKFDKVLEDISPKLKESFDYMKKYDLYDY
                     SSGKNKSPGGYTTYINKYKAPFLFNTWDNSFLGVTSFAHEFGHFYNYYNSINLNNKMQ
                     PSIDVCEVHSTSLEILFYKYFDDFFGKQSEAIKKEHLSIVLNTIIDACLYDEFQEIIY
                     KNPYMNLNDINKLFFDLEEEYGVSNNILREKNAPFWILVSHNFQVPFYYLSYGLASDV
                     SLQIWQLSQEDYRKAVDVYMDFLNQNTDAGFKDVVEKVNLQLPFQDGNLEEISSTLYD
                     YFGIDNPLELKNAS"
     gene            4309..5685
                     /locus_tag="KRH23_003667"
     CDS             4309..5685
                     /locus_tag="KRH23_003667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0015079 - potassium ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HHS5226931.1"
                     /translation="MKTIVRRLILYADGMRPTQIMVSGFAAIIVIGALLLTLPIASQS
                     GESIGLLNALFTATSAVCVTGLVMVDTATYWSLFGQIVIITLIQIGGLGFMTVATMFS
                     LMARKKIQLRERLLIQESLNQADLSGLVRLTRFVLIITITIEGIGALVLSTVFIPQFG
                     LSKGIWYSVFHAISAFCNAGFDLMGSVSGPFTSLNSYVNNFTVSMTVCALIVLGGLGF
                     PVVLDIVRKRRFSKLNVHSKVVLFSTATLIFVGALFIFLIEFNQKATMADLPLKGKVL
                     SAIFQSVTARTAGFNTLDLATLRESSVFVMIILMFIGASPASTGGGIKTTTLAVLIIT
                     VRSFLSGKSDIEAFERRLAPSTIKKSLGIFVISISAVIFGTLIISITQPNFTLVQSAF
                     EVTSALATVGSSLAGTPNLNALGKIIIIIFMFMGRVGSLTLFMAILSGGRRKSQPIRY
                     AEGKIMVG"
     gene            5996..6667
                     /locus_tag="KRH23_003668"
     CDS             5996..6667
                     /locus_tag="KRH23_003668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA];
                     GO_process: GO:0034220 - monoatomic ion transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="potassium channel family protein"
                     /protein_id="HHS5226932.1"
                     /translation="MKQYIVIGCGRFGSSVASTMHLLGHQVMAIDKNEDSVQSISDKV
                     THSLIVDVTDEQALRSLGLGNFDVAVVAIGSDIRASIMATLIAKEMGVELIICKAKDE
                     LQAKVLYKIGADRVVFPERDMGVRVAHNLVSDNILDHIELDPEYSIVEIVTPNSWVGK
                     TLIELELRARYEITVLAIKTGKNINVTPSPDEELTAGSILVIIGQNTSITAITSGNKG
                     IIRRR"
     gene            6856..7653
                     /locus_tag="KRH23_003669"
     CDS             6856..7653
                     /locus_tag="KRH23_003669"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrmH family RNA methyltransferase"
                     /protein_id="HHS5226933.1"
                     /translation="MITNINSKDNEKLKYTRALLKSKNRNKESKFIIEGYRIVMLALE
                     CMANLDYVFINEEFENKKEHVKLLEDLDKKNTKIYKTTNKNFKELVDTENTQGIIGVV
                     SFKKKKLSESINKKDKFVLILDRIQDPGNMGTIIRTADSAGVDAIIALKGCVDIYNPK
                     VIRSTMGSIFDMNIIDASQDETVDMLKSLDFNIVSSYLNTENFYDKIDYGSKVALVIG
                     NEANGINEELVSKSDILVKIPIYGKAESLNAAISSAILMYEIKKYLI"
BASE COUNT         2841 a          944 c         1204 g         2730 t
ORIGIN      
        1 aatcaaattc taggtattta aacataacat cacaagtgat ttatctgaca aattaagata
       61 atatcctaat taaattgtag gtatttaaac ataacatcac aagtgattta tctgaaaaag
      121 taagataata tactaattaa attgtaggta tttatacata acactaaaag taatttgtct
      181 aacaaattaa aatattatcc aatttaatat aaaaattact tctttttaac tgggaagcat
      241 acctctgtta cccaattatc aggattacta tcgttgccag gacttacatg ataaatatta
      301 aacataggac catccacctc atagttatta tctgatatcc aattaccaat agcctcacaa
      361 gcgtctgcaa cttgattgaa atttccatta acaattgcag ttgcagcagt cacacttgga
      421 acagtcttaa atttaacatg ttcagtatct ttatactttc cagatacagc aacttgtact
      481 tcaacatcta cataatcttc tttatatcca gtatcataaa aaactgcttt agaatacttt
      541 gggggttcaa tttgaacatt ctggtctttt gtctctaaaa atgcttgatg ccataacatt
      601 ccttcgtctt gataagttgg tataaccctt ctaagtgtca tcatatattt tggtgcaaaa
      661 ttctttatag ttacatcata atttttcata atatcatttc ctccaattct tttaatagtg
      721 gtttctattt ttaatagttt tttctgtgta tcttctaatt gttcttttac ttgagaatga
      781 tggatattta gatattttat gagactttct ttatcgttat attctgtcaa aatttctttt
      841 atagaataca agccaaagcc catatctttt agtgcatgga ttctgtttgt agtagaaagt
      901 tggtctgcac tatagtatct atatccatta gttttattcg tatgagaagg agttaaaagt
      961 cctatttcat cataatgacg taacatacga atactaattt tacttagctt tgaaaaatcg
     1021 cctatcttaa acatgttttt gtctccttta taaaggtact tttagcttaa tattaatata
     1081 aaccatatca taatgttaga gtcaactaaa attataatta aattatattg acatatgatg
     1141 aaaaaaatat tatactgaac atgttcagaa ccgaaaatgt taattgtttt ggaggtctat
     1201 tatgaaaagt aatgataaag atgctagaga acgtataatt gaagttacat tgaatctttt
     1261 aaatgaagta gatgatattg aggaaattac agttagaaaa attgctgagc gtgcaaatgt
     1321 tggagttggt ttaataaatt atcattttaa aacaaaggat aatttgttga gtactgccat
     1381 aggagatgtg atgtcaaata taatagcaga gctatatgac gatagtgtat atactctaag
     1441 acctattgaa gatttgaaaa atttattaaa aaaattgtgt gatactggat tacattatga
     1501 aaaagtgctt ccttttgtat tgaatcaatg tataaccaat ggagatatgc aagcagaact
     1561 tgatattgtc cctatgcttc gtaaaatttt tggaaataaa aaagatgaaa tgagtctaag
     1621 aattattgcc ctgcaaatta ttttaccaat acagatttct gctttatcta cagaatcatt
     1681 tcagttatac agtggtataa atataaagaa taaatatgag cgagataaat tcattgatat
     1741 tttaatagaa aatattattg gagaggatgt tgatgtaaga tgaaaattat aactattggt
     1801 tcaagtctta tcactgtttt actttttctt tcaactatgg tttgtgggtt ctggattaag
     1861 aataataagg taacagatgc aagttctatt aagttccata tgaatagtgc tatttttaca
     1921 gggatatttt tattgatttc cacaatcttt ttaattatat atataaaaaa ataataatat
     1981 tattaataaa taaagtatca gaaattataa agacaagagt cttaaaaatt tctgatactt
     2041 taccatataa ttttattaaa cattaattgt gtgtgaaaaa atatcactta tttcaatcta
     2101 atactaaatc ttaagaatga gtataaagta ttagaaatta agaagcattt tttagttcaa
     2161 gtggattatc tataccaaaa taatcatata aagtagagct tatttcctct aaatttccat
     2221 cttggaaagg taattgtaaa tttacctttt ctaccacatc tttaaatcca gcatcagtat
     2281 tttgatttaa aaaatccata tatacatcaa cagcttttct gtaatcttct tgtgataatt
     2341 gccatatctg aagtgataca tcagatgcaa gaccataact caagtaataa aaaggaactt
     2401 ggaagttatg agatacaagt atccaaaaag gagcattttt ttctctaagt atattattgg
     2461 aaactccata ttcttcctct aaatcaaaaa acaatttatt gatatcattt agattcatat
     2521 atggattctt gtatataatt tcttgaaatt catcataaag acaagcatca ataatagtat
     2581 ttaaaacaat cgataagtgt tcttttttta tagcttcaga ttgtttacca aaaaaatcat
     2641 caaaatattt ataaaataga atttctaaag atgttgaatg aacttcacat acatctatac
     2701 ttggttgcat cttattattt aagttaatac tgttgtagta attataaaaa tgaccaaact
     2761 catgagcaaa actagtaaca cctaaaaaag aattgtccca tgtattaaac aagaaaggtg
     2821 ctttatattt atttatataa gtagtatatc ctccaggtga tttgtttttt ccagaagaat
     2881 aatcgtacaa gtcatatttt ttcatatagt cgaagctctc ttttagtttt ggagatatat
     2941 cttcaagtac tttatcaaac ttcctaaatg agcgattttt atatacttta atataaatag
     3001 aagaatcaga tggtttagat gaaatctctc tatataatgg aactatgtaa tcttttacat
     3061 cttgtctaaa ttttttagct tcttcttgag aatagtcttt gtttaggttc atataggcat
     3121 aatctatata attcttaaat ccttgcttac ttgctatttc agttcttgtc tgtataagtt
     3181 ctaagaatat gttaccaaat ataggattgt atttttttaa gtaatctgaa taaattttca
     3241 catattcttc agggctaaga tttggtcttg acaaggcttc ttcaaagtct acctctatac
     3301 catctattga tactgtagat ttagctaata aatcttcata ttttacaact aggtcttgct
     3361 cttttttaag caaaccttca acttctttag aattaagttt tccaatgttc tttagataat
     3421 taaatgtatc ctttccaagt tctttttcta attctttaga gaatttagaa gttacaaatc
     3481 tatcttgaaa gtctttgtat gacatgtcaa catctactga tttactcata agatacttat
     3541 attccttaga gtaaaattcg tctgatgaat ctatgttatt tctaattttt gctatagtaa
     3601 gtgtactgta aaaatcctga taaattttat caacttcatt aaataaattt aattgttcct
     3661 tagctgtttt agctgttaaa agtttgtcgt tacacttgtt aatgttttcg caaattgact
     3721 gtatattagg acgcttatat tccatttttt caaaaggaat agttcctcta acagaatctt
     3781 tttttgtatc attagtataa tttcttatgt atgatgcaaa tataataaaa actgcaatta
     3841 aaattagaaa aacaaatatt ttcttcttgg atttaaccat aaaaatcctc caatcatgga
     3901 tatagttatt aattatttta ctatattaaa tataaaaaat gcatgttaag aaaatttaac
     3961 ataaagatat agataagatt ataaataata taaaaaattt aacttcaaaa aagtatatga
     4021 aatttatact ggtaaaatga taaataaatt ttaagtacaa aatagtaaaa gctatgatag
     4081 ttttagacct attatatgta aaaaatatag atgtttttgg tgcaatttaa attaaaagat
     4141 atatataaaa atttaaaata ttccaaacag aaattataaa aattactatc attgtcttta
     4201 tacaatattt atactataat agaataataa tttagaggaa agctctaaaa ataaacaaat
     4261 taagggtctt aacagtagtg attttatgtt aaggaggtat aaagaaagtt gaaaacaata
     4321 gttagaagac ttattctcta cgcagatgga atgcgtccta ctcaaataat ggtatctggg
     4381 tttgctgcga ttattgtaat cggagcattg ttgttaacac tcccgatagc gtcgcagagt
     4441 ggagagagta taggcttatt aaatgctcta tttacggcta cttcagcggt ttgtgttact
     4501 ggtctagtta tggtagatac agcaacttat tggagtttat ttggacagat agttataata
     4561 acattgatac aaattggtgg tcttggattt atgaccgtag ccacaatgtt ttcacttatg
     4621 gcacgaaaaa aaatacaact aagagaaaga ttattaatac aagagtcatt aaatcaagct
     4681 gatttatcgg gacttgtaag acttacaaga tttgtattaa taataaccat aacaatagag
     4741 ggaataggtg cactggtttt atcaactgtc tttattccac aatttggttt gtctaaaggg
     4801 atatggtata gtgtatttca cgcaatatca gcgttttgta atgccggatt tgacttgatg
     4861 ggcagtgtaa gtggcccatt tacatcgtta aattcttatg taaacaactt tacagtatca
     4921 atgactgttt gcgcacttat agtgcttgga gggctaggat tccctgttgt acttgatatt
     4981 gtaagaaaaa gaagattttc aaaattaaat gtgcattcta aggttgtatt gttttcaact
     5041 gctacactta tttttgtggg tgcattattt atttttctta tagaatttaa tcaaaaagct
     5101 actatggcgg acttgccttt aaagggaaaa gtactatcag caatatttca atcagtaaca
     5161 gcaagaactg ctggttttaa tacgcttgat ttagctactt tacgagaaag tagtgtattt
     5221 gtaatgataa ttttgatgtt tattggagca tcacctgcat caactggtgg gggtataaaa
     5281 acaacaacac tagctgtttt aatcattaca gttagaagtt ttctatcagg aaaatcagat
     5341 atagaagctt ttgaaagaag attagctcca tcaactataa aaaaatctct tggtatattt
     5401 gtaatcagta tatcagcagt tatttttgga acattgatta tttcaataac tcagcctaat
     5461 tttacattag ttcaatcagc ttttgaggtt acatcagcac ttgctacagt tggttcaagt
     5521 ttagctggaa ctccaaactt aaatgcttta ggtaagatta taataataat ctttatgttt
     5581 atgggtagag ttggttctct tactttattt atggctatac tttctggtgg tagaagaaag
     5641 agtcaaccaa tcagatatgc agaaggtaaa attatggttg gttaagttac caaggagtaa
     5701 tataaattta taatggattt agagtagcac tgtaaatctg ttgataaaat aaatgagcct
     5761 agatgtaatt atatgaagaa ataaaatcga ctaacgaaca aaattaatta atgaaataaa
     5821 aaaacaggga aataaaatac aaataaaaag gtaaatcaaa attaaattaa tctgtgtata
     5881 taaaattata tattgtgtat aagttttgta tgtgtaaagt atataagttt tgtatgtgta
     5941 aacaattaat ttaagagata ttatataaat tgtgtattag ggaggaagtt tcgagatgaa
     6001 gcaatatata gtcattgggt gtgggagatt tggaagttca gttgcgtcta ctatgcatct
     6061 tttaggacat caagtaatgg caatagacaa aaatgaagat tcagttcaaa gtatatctga
     6121 caaggtaacc cattcactta tagtggatgt tactgatgag caagcgttaa ggtcattagg
     6181 tttaggtaac tttgatgtag cagtagttgc aataggttct gatataaggg catctataat
     6241 ggcgactctt atagccaaag aaatgggtgt agagttgata atatgtaagg caaaggatga
     6301 attacaagct aaagttcttt ataaaattgg tgcagataga gttgtatttc cagaaagaga
     6361 tatgggagta agagttgcac acaatttagt ttcggataat atattagacc atattgaact
     6421 tgacccagag tattcaattg ttgaaatcgt aactccaaat agttgggttg gcaagacact
     6481 tatagagctt gaattaagag ctagatatga gataactgta cttgctataa aaacaggtaa
     6541 aaatataaat gttacacctt ctccagatga ggaacttaca gccggaagta tcctagttat
     6601 aatcggtcaa aatactagta taacagcgat aacatctgga aataagggga taattagaag
     6661 aagataattt actatttaat atatatttaa ttgcaatgaa agtagatagt atcatataat
     6721 tatgaatagt tatatgatac tattttttta atcgaaggta gtatttattt gtaagattag
     6781 ataaagagaa gttaaattaa aagtaaggag gctgtgctaa tataaaaatt tataagttat
     6841 tagcatttag ataaaatgat tacaaatata aacagtaagg ataatgaaaa gttaaagtat
     6901 acaagagcac tattaaaatc aaagaatagg aataaagagt caaagttcat aatagaggga
     6961 tacagaatag taatgcttgc acttgaatgt atggcaaacc ttgattatgt atttatcaat
     7021 gaagaatttg aaaataagaa agaacatgta aaactattag aagatttgga taaaaaaaac
     7081 acaaagatat acaagactac taataaaaac tttaaagaat tagtggatac agaaaatact
     7141 caaggaataa taggtgtagt ttcatttaag aaaaaaaaat taagtgaaag tataaataaa
     7201 aaagataaat ttgtattgat tttagacaga atacaagacc caggaaatat ggggactata
     7261 ataaggactg ctgattctgc tggagtagat gccataatag cactaaaggg atgtgtcgat
     7321 atatacaacc caaaagtaat taggtctact atgggttcta tttttgatat gaatataatt
     7381 gatgcttcac aagatgaaac tgtggacatg cttaaatcat tggattttaa tatagtttca
     7441 agttacttaa atacagaaaa tttttatgac aaaatagatt atggctcaaa agtagcattg
     7501 gtgataggaa acgaagcaaa tggaataaat gaagaacttg tatcaaagtc tgatattttg
     7561 gttaagatac ctatatatgg taaagccgag tcgttaaatg ctgcgataag ctctgctata
     7621 ctgatgtatg aaataaaaaa atacttaatt taatgtattg taataaatat aatgtcatgt
     7681 tataatcttg aattaaatag tagagtatca aaaatagtc
//
LOCUS       DAEORM030000106         6724 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.112, whole genome shotgun sequence.
ACCESSION   DAEORM030000106 DAEORM030000000
VERSION     DAEORM030000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6724)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6724)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 6724)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6724
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.112"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            428..1702
                     /locus_tag="KRH23_003670"
     CDS             428..1702
                     /locus_tag="KRH23_003670"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0031071 - cysteine desulfurase activity
                     [Evidence IEA];
                     GO_process: GO:0006534 - cysteine metabolic process
                     [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HHS5226934.1"
                     /translation="MQFMDVSKYIEGANLKVKTKNGETVKRIYFNNSATPLVLKNVMD
                     NLNCEIPWLTYINAPGIISEKNTLKYENVRSTILKLIDGDEEKDSVIYVKNATEGINF
                     LAKFFKDENPDKFVITTAMEHMANYLPFKVNFPTKVVGITEKGELDLCQLENILKNYA
                     GNVSLVTVTGASNVTGITTPIYEIARIAHKYGAKILVDIVQVIQHKPFSMMPHECDEH
                     IDFVVFSAHKCYSPLNGGALVGPKKFFEKFNPVLYGSGSTKFVNDNKILYANVPQRFE
                     AGYPEYFGTLAMGKALNTLNKIGLNRISKYERELFLYAKEEMSKIPNIIIYGDKSNNV
                     IIPNISFNISNMYYKDVAKYLVDNFGIETGAGVVGADIYVQKLLGINPKEAYVRFMRE
                     NPVGLVRISLGMYNTFDEVDSFIHAIKTLAFK"
     gene            complement(1909..2226)
                     /gene="trxA"
                     /locus_tag="KRH23_003671"
     CDS             complement(1909..2226)
                     /gene="trxA"
                     /locus_tag="KRH23_003671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015035 - protein-disulfide reductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HHS5226935.1"
                     /translation="MVKIINNNEFINEVENKDGLVVVDFFATWCGPCKMLSPIYEALG
                     NEMVEKANFLKVDIDQSIELAQKFEVSTVPTMLIFKDGKPVDRLIGFMPKENLKNKIE
                     SYM"
     gene            2493..3245
                     /locus_tag="KRH23_003672"
     CDS             2493..3245
                     /locus_tag="KRH23_003672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0140110 - transcription regulator activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrmB family transcriptional regulator"
                     /protein_id="HHS5226936.1"
                     /translation="MDNIINELQNIGFTKYESQIYISLLKESPLTGYEISKLSGVPQS
                     KVYENITKLLNNNIIINVGTDPIKYIPINPNELLKNKKKEFDNSMDNLKNSLQILNKS
                     KSVEYVLNIKGDKNILKKAIEMIKNAKQEIIISCPYEEILELKKELLIAYKKNINIEI
                     LLLENKSLKGLDNIHIHGGNKTTLENKMLYKGIILIVDNDEILTGNLSEGSEAISIWT
                     KNSNILYIGVQYIKHEIYISEQIKGGYKNEQN"
     gene            3232..4113
                     /locus_tag="KRH23_003673"
     CDS             3232..4113
                     /locus_tag="KRH23_003673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HHS5226937.1"
                     /translation="MNKIKIKQVDAFTTIPFGGNPAGVVTDASNISDEIKQNVAKEMN
                     LSETAFVSESNVADFKVQFFTPGLEVDLCGHATIGTFHALLEEGRLNTNKSIFYQETK
                     AGVLSVELKEINNENIFMMEQNTPEFENLDNCRKELAQMIDVHEDRLLEYPIIKVNTG
                     LWWLVFGLKSLDDLKNISPDLNKIKKFSGDNNIIGITPFCIETIDKKCDYHLRSIAPY
                     VGVTEDPVCGTGNACVSSYIVHHNILDKTSFIGEQGNFINRPGKVYVNITRENNDITS
                     VKIGGNAYTVLSGEIMY"
     gene            complement(4339..5694)
                     /locus_tag="KRH23_003674"
     CDS             complement(4339..5694)
                     /locus_tag="KRH23_003674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_function: GO:1904680 - peptide transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015833 - peptide transport [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HHS5226938.1"
                     /translation="MSSTVKKKGKFPMGFYICSTTFSFERAAYYASKYLIYIFLTTAI
                     VHGGLGIDKGQAAIMQANLVAFTYLAPIIGGYISDRWIGARYTIPIGMLIMGVGYYLG
                     SIATTVSMVNAMIILVSIGTAFFKGNVSAVNGQLFDSQEELDTAFSVQYSFVNIGSFI
                     GTIAVGILYLKTFAKNGVLGFSQCFFIAAVLCVIGAIWFIYGWRFLGNAGKRPFKEGV
                     VAEKIEEKDKSPLTSMDKKRIWAIILISFFSVIFWVFWYLTYLAVYDYGAAFVNMNVG
                     GFDVPLAWFDSLNSLVCIVLGPVLGALWFKLASRPQGDMSLFKKTGLGLIFLGLAFLM
                     LVGAEFSRGVGAPETAKASILWIIMFGILLSLGEMLFSPLGNSFVSKYAPKKLLGVLM
                     GVWTFATFIAGKGYGYIYAFTLKFDMIKVYTIIPVILFVAAILLFLSDKTLSRLVEDD
                     K"
BASE COUNT         2593 a          957 c          836 g         2338 t
ORIGIN      
        1 tatacttgta catcttttat aacatataaa atcttttttt ctaattatat acaatatatt
       61 ttccattatg ttctaatcaa tttctttact atttttacaa ctttattagt catattcata
      121 attatttcta attagtgttt aacattttat gtaaaattta taaaaaaatg tatataaatt
      181 aaaataagtg actatactaa aaatatgata cggataaaca ataagttcaa cctatctccc
      241 ccaaaatcaa gtgagctaca gtttccccca actgtagctc attttcgtgt aatttaataa
      301 acatctcaac aagaattaat taacaaaacc ccttataaaa acataacata tattaaacaa
      361 gctcttgatt aaaacttgag cttttttaat aaaaaacaga atagtttatt agataagggg
      421 tttttttatg caattcatgg atgtatctaa atacattgaa ggtgcaaatc ttaaagttaa
      481 aactaaaaat ggtgaaactg ttaaaagaat atattttaac aactctgcca ctccattagt
      541 tttaaaaaac gtaatggata acttaaactg tgagattcct tggcttactt atattaatgc
      601 tccaggaata atctcagaaa aaaatacttt aaaatatgaa aatgtacgct ctactatcct
      661 caaacttatt gatggagacg aagaaaagga ttctgttatt tatgtcaaaa atgctacaga
      721 aggaataaac ttcttagcaa aattttttaa agatgaaaat ccagataaat ttgttattac
      781 cacagcaatg gagcatatgg ctaattacct gccttttaaa gttaattttc ctacaaaagt
      841 tgttggaatt acagaaaaag gagaacttga tttatgtcaa ttagagaata tacttaaaaa
      901 ttatgctggt aatgtatctc tcgttacagt tacaggagct agtaatgtca caggtataac
      961 cactcctata tatgaaatag caagaatagc tcataagtat ggtgcaaaga tattggtgga
     1021 tattgtgcaa gtaattcagc ataaaccttt ttcaatgatg ccacatgaat gtgatgagca
     1081 tatagatttt gttgttttta gtgctcataa atgttattct ccactaaatg gaggagctct
     1141 ggtaggacct aaaaaattct ttgaaaaatt taatcctgta ctatatggct caggttctac
     1201 caaatttgta aatgataaca aaatactata tgcaaacgta ccccaacgtt ttgaagcagg
     1261 atacccagag tattttggaa ctcttgcaat gggaaaagca ctgaacactt taaataaaat
     1321 tggtctaaac agaatttcaa aatacgaaag agaattattt ttatatgcta aagaagaaat
     1381 gagtaaaata cctaatataa taatatatgg agataaatca aataatgtaa ttatcccaaa
     1441 tatatctttt aatataagta atatgtatta caaagatgta gcaaaatatt tagttgataa
     1501 ctttggaata gaaactggag ctggagtagt aggtgcagat atttatgtac aaaaattatt
     1561 aggtataaat ccaaaagagg catacgtcag atttatgagg gaaaatcctg taggtcttgt
     1621 taggataagc ttaggaatgt acaatacttt tgatgaggtg gatagcttta tacatgctat
     1681 taaaactttg gcttttaaat aagctttttc tattcttttt tatcaataaa tagagagtag
     1741 ttttgttttc acaaaaaagc aaattatatc aacagtcaat ttcattagca attagacact
     1801 catttgtaac tatacaaact attttacact atacaaacaa aaaactcatt acaatgagtt
     1861 tttttgttta tatatgagat ttattttaat tacttcaatt tactttaatt acatatatga
     1921 ttcaattttg ttttttaaat tctccttagg cataaaacct attaatctat ctacaggttt
     1981 tccatcctta aatattagca tagttggtac tgtagatact tcaaatttct gagctaattc
     2041 tatactttgg tctatgtcca ccttcaagaa gtttgctttt tcaaccatct catttcctaa
     2101 agcttcatat attggtgata gcatcttaca aggtccacac caagtcgcaa agaaatctac
     2161 aactactaaa ccatctttat tttctacttc atttataaat tcattattat ttattatttt
     2221 taccataata tacatctcct ttattatctt cttgatatta atatactacg ccctatataa
     2281 cagttcaatt aggcactttt ttgtaaccgc ctatttttaa taggtttaat attatgataa
     2341 atagatttat aagattaaat atttataaga ctaaatattt ctaatatatt ttattttttt
     2401 cttaatatag ttgacatttt ttcccttaaa ttataaaatc aaattaataa ctacataggt
     2461 agttactaat cttttatcaa aggagtttct atatggataa tataattaat gaattacaaa
     2521 atataggatt tactaaatac gaatctcaaa tatacatatc attattaaag gaaagccctt
     2581 taacaggata tgaaataagt aaattatcag gtgtaccaca atcaaaagtc tatgaaaata
     2641 taacaaagct attaaacaat aatataatta tcaatgttgg aactgaccct attaagtaca
     2701 taccaataaa ccctaatgaa ttattaaaaa ataagaaaaa agaatttgac aattctatgg
     2761 ataatctaaa gaatagctta cagatattaa ataaaagtaa aagtgtagaa tacgtattaa
     2821 acataaaagg agataaaaat atattaaaaa aagcaataga aatgataaaa aatgcaaaac
     2881 aagaaattat aatttcttgc ccttatgaag aaattcttga attaaaaaaa gaactcctaa
     2941 ttgcttacaa aaaaaatatt aatattgaaa tactactttt agaaaacaaa agtctgaaag
     3001 gtcttgataa tattcatatt catggaggta ataaaactac acttgaaaat aaaatgcttt
     3061 acaaaggaat tattttgatt gtagataatg atgaaatatt gacaggaaac ttatcagaag
     3121 gcagtgaggc catttcaatt tggacaaaaa actctaacat tttatatatt ggagttcaat
     3181 acataaaaca tgaaatttat atttcagaac aaataaaagg aggttataaa aatgaacaaa
     3241 attaagatta aacaagttga tgcttttaca actatacctt ttggtggaaa tcctgctggt
     3301 gtcgttactg atgcctctaa catttctgat gaaattaagc agaatgtggc taaagaaatg
     3361 aatttatcag aaactgcatt tgtttcagag tcaaatgttg cagattttaa ggtacaattt
     3421 ttcacaccag gtttagaagt tgatttatgt ggtcatgcaa caataggtac tttccatgca
     3481 cttttggaag aaggaaggct taatactaat aagagtatat tttatcaaga aacaaaagct
     3541 ggtgtattat ctgtagagct taaggaaata aataatgaaa atatatttat gatggaacag
     3601 aatacacctg aatttgaaaa tttagataat tgcagaaaag aacttgcaca aatgatagat
     3661 gtgcatgaag atagacttct tgaatatcct attataaagg taaatactgg actttggtgg
     3721 cttgtatttg gtctaaaatc tttagatgat ttaaaaaata tctctccaga tttaaataaa
     3781 atcaaaaaat ttagtggtga taataatata attggtataa ctccattttg tatagaaact
     3841 atagataaaa agtgtgacta ccatttaaga tctatagcac catatgttgg agttacagaa
     3901 gaccctgtat gtggaactgg gaacgcttgc gtatcatctt atatagtaca tcacaatatt
     3961 ttagataaaa ctagttttat tggtgagcaa ggtaacttta taaacagacc tggaaaggta
     4021 tatgtaaata taactagaga aaacaatgac ataacttctg taaaaattgg aggaaatgct
     4081 tatactgttt taagtggtga aattatgtat taatcccata cctaataaaa acaaataaaa
     4141 atactagcta actaaagcta gtatttttat ttgttatttt tatttaataa tcatactcta
     4201 acaaatacta taattatata tatcataata ttgtatttag aagtaaaatt ttatttttat
     4261 tattaattag ttataaatca atctaataca acataattac agtagattaa cctataaaac
     4321 ataataattg cttactaatt atttatcatc ctcaacaagt ctacttaatg tcttatcaga
     4381 taagaataat aatatcgctg caacaaatag tattactgga attatagtat atactttaat
     4441 catatcaaat ttaagagtaa atgcatatat atatccgtat cctttaccag ctataaaagt
     4501 agcaaatgtc catactccca taagaacacc tagaagcttc ttaggtgcat acttacttac
     4561 aaaagagtta ccaagtggtg agaataacat ttcaccaaga cttaaaagaa taccaaacat
     4621 gattatccat agtatactag ctttagcagt ttcaggagct ccaacccctc ttgaaaattc
     4681 tgcaccaaca agcattaaga atgcaagacc taagaatatt aatccaagac ctgtcttttt
     4741 aaataaactc atatctcctt gtggtctact agcaagttta aaccataatg ctccaagaac
     4801 tggtcctaat actatacata caagtgaatt taatgagtca aaccaagcaa gaggaacatc
     4861 aaatcctcca acattcatgt ttacaaatgc tgcaccataa tcataaactg caagataagt
     4921 tagataccag aatacccaga aaattacaga gaagaatgat ataagtataa tagcccaaat
     4981 tctcttctta tccatgcttg taagaggaga cttatctttt tcttcaattt tttcagcaac
     5041 tacaccttct ttaaaaggtc tctttcctgc attcccaagg aatctccatc catatatgaa
     5101 ccatattgca cctattacac aaagtacagc tgctataaag aaacattgag aaaatccaag
     5161 tacaccattt tttgcaaatg ttttaaggta aagaatacca actgctatag taccaataaa
     5221 agaacctata ttaacaaaag aatactgtac tgaaaatgct gtatcaagtt cttcttgact
     5281 atcaaaaagc tgtccattta ccgcagatac gttaccttta aagaatgcag taccaattga
     5341 aactaagatt atcattgcat ttaccataga aactgtagtt gcaatagaac caagatagta
     5401 tcctactccc atgataagca tacctatagg tatagtatat ctagctccta tccatctatc
     5461 tgatatatat cccccaatta taggtgcaag gtatgtgaat gcaacaaggt tggcttgcat
     5521 tatagcagct tgtcctttat ctattccaag accaccatga actatagctg ttgtaaggaa
     5581 tatatatatt aagtactttg aagcataata tgctgctctt tcaaatgaga aagttgttga
     5641 gcagatataa aatcccatag gaaatttacc cttctttttt actgttgagc tcataatttt
     5701 aaatcctttc ttaattgtat ttttattttt tacgttttgt ccaaattctt tcttttatga
     5761 aagatataat attattattt tgtaaaacaa tttgtaatta ttattaagat aattgcgcat
     5821 ttatttgtag agtacatatt ctcatggaat aaaattaata cacttcttaa tcataaattt
     5881 aaattatata aattcactat tttcagatat agttataaat taatatattc tcatctaata
     5941 ccatgaaaaa accttcgcca tatgcaattc ttatttttta cgtgatagta ttttacaaac
     6001 taaaatcccc cttttgtagc aacttatgta attacatttt agtgcttttt taaaggagtc
     6061 tcgaataaag caacatatat ttgttcaaat aatgttttta tttatttttt aaatttatat
     6121 attacttcac tcaaccaatt ctcaacttaa ataaataaac tactatctat tcacagatta
     6181 gacatatttc ttacacatta gtttataata aacactgtga atctaaacat aaaaactgtt
     6241 attttaaagt aattacccat atattcgctt tgatactatt tattgaggtt atactcttta
     6301 tgtataatat attatttata aaatacctca aaatatatta ttcataaaat acctcaaact
     6361 gaaaactttt tcacgaatat ttatttttca cctccccttt tttatttcac catgtaaatc
     6421 gtaccataaa tatgcactta tatgcaagaa aaaaatctat taatcgacag taaataatta
     6481 gaaaaattca aattatattt atcaagtata ttatataaaa tatttcctat gaaaatataa
     6541 attaaattaa tgttcagaat tgtttttaga tatgaaatct tgattttttt attactttac
     6601 ttatttgctc aaatatattt ttgtatgcag tatataataa tcaaattata cacttcttat
     6661 aactgcattg atttgaaaat aatattaata attaatagaa taaaaaattt aaattaaatt
     6721 taaa
//
LOCUS       DAEORM030000107         6506 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.113, whole genome shotgun sequence.
ACCESSION   DAEORM030000107 DAEORM030000000
VERSION     DAEORM030000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6506)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6506)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 6506)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6506
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.113"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     misc_binding    394..632
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            696..2615
                     /gene="thrS"
                     /locus_tag="KRH23_003675"
     CDS             696..2615
                     /gene="thrS"
                     /locus_tag="KRH23_003675"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004829 - threonine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006435 - threonyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HHS5226939.1"
                     /translation="MIKVALKDGSIKEFENAISVMDVAKSISEGLARNVVAASVNGEV
                     VGLDHIIDTDCDLNLFKFEDKEGKEVFRHTSAHILAQAIKRLYPEAKLAIGPSIENGF
                     YYDIDLDHRLVPEDLEKIEAEMKKIAKEDLKIERFELPRNEALELMKEQGEDYKVELI
                     SDLPESEIISFYKQGDFTDLCRGPHLPSTKKVKAVKLQSVAGAYWRGDENNKMLQRIY
                     GTSFEKNKDLEEYLHLLEEAKKRDHRKLGKELGLFMIPEEGPGFPMFLPKGMELKNEL
                     LKFWREIHRKAGYIEIESPIILNRKLWETSGHWYHYKENMYTVKIDDEDYAIKPMNCP
                     GGLIYYNSQLHSYRDFPMRVAELGRVHRHELSGALQGLMRVRAFTQDDSHIFMLPEQI
                     KDEIKGVANLIDGIYKTFGFEYNLELSTRPENSMGSDEEWEAAENGLREALEELGLPY
                     TINEGDGAFYGPKIDFHLKDCLGRTWQCGTIQLDMQLPRQFDNTYIGQDGEKHRPVMI
                     HRVAFGSIERFIGILIEHYAGKFPVWLSPTQVKILPISDKFMDYANEVKKELFDKGIR
                     VELDDRAEKIGFKIREAQLEKVPYMLIVGEKEVADNNVSVRSRDKGEIGSIKLDEFIA
                     SISKEIESRESIIQD"
     gene            3382..4398
                     /locus_tag="KRH23_003676"
     CDS             3382..4398
                     /locus_tag="KRH23_003676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="HHS5226940.1"
                     /translation="MIEKVEEKSKIIKTSKEYKRTIIEEKDKEWTKKLNDILSRSSFS
                     NDELDKIKALIPKEILTNENVGEVVTEDGYAKPEYDEVFKSLFTLNNEYDLLVNFIND
                     ILKDAPYANRNIKPFTQIKRIIRVETDPTINYIGEKRPRLDILAEDEENNHINIEMQR
                     AFENDYLERAEYYLSRVHSRKLEEGKEYKEIGKTIGIHILNHVKYNHIEDYVNCLRLT
                     MDGHPDIYSSKTALYFIELPKIHKSDYIVNRIMLWGKLISNPSNLDVRVIAKNDSIIK
                     KALDRLKELGSNEEYLLNLKRGAYIMNKSRNFKEEIERETAIRVAKEKDYKIIIMLKK
                     MVLN"
     gene            5141..6481
                     /locus_tag="KRH23_003677"
     CDS             5141..6481
                     /locus_tag="KRH23_003677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HHS5226941.1"
                     /translation="MIKSSLFWNIFIAISFMIEWFLCKKMLDYTSEKRISNKKINFCV
                     VGIIVFADIIYFFDVPPNIIVIISMIITIAFYKISYDVGFIKSVLISLIYWMLLIATD
                     ALSISLTVWLNSINDMSSMGTGDIYRIESIILGKILLIVSLLLYRALKIKLNIEINKR
                     TLFYIVIPIVANIASFFVIFEYIFNPGSGSLIHNFQFVMISVVLLISSITLVLIAKKL
                     QQYNTLVVENNMIKNTLKYENEYYEDIEKKYLKTRLLSHDMKNHILCINAMIKKGIDV
                     TSYLNNLQVEIQSNDLLFNTGNFILDAILSEKKEVCDKNDIELKIGINFSCCEAVELV
                     DICHIFSNILDNAIEACNKIDSGNRVICVKGDVMQNFYLIRVENTKINKIITKNGDIL
                     TDKKGSLHGLGIKSVKNSVNKYGGNVVIEYDDKKFVVKIAIPLRNVKKAVNHVI"
BASE COUNT         2562 a          604 c         1120 g         2220 t
ORIGIN      
        1 aatagcattt agatattaat tgtatttatt tatttgattg tgttacttat taatagtatt
       61 taagtattta ctgtactact tattaaccat attaagtatt gattgtattt aagtatacaa
      121 aacctaaaaa gagtacaaaa attagaagtt agttttaata aaaattagtt ttagtattta
      181 tctagtcata tctatcatgc atgtggatac gttttaaaaa ttttaaattt atgaaaatat
      241 tataatatca ctataaatca agagattaat ttaatataaa aatataagaa tattggttta
      301 cagctgattg agatgaaaaa taatgggtaa ttaatatatt acattaatgt tgattgatgt
      361 ataactatct gttataatga aaatatatta aaaatcatag tgttgaagag gaagagtaga
      421 gtagaaacca ttctcagaga atttgggtct atggctgaga gcccatgtaa taggtctatt
      481 tgaaaactac cttggagctg agcttattag cagtatttgt atttgtacta tacgtgaaag
      541 tgctcgggtg acgaccttat agtcatcaag agggttgtat atacttgtat acgccaactt
      601 gggtggaacc gcgaattaat atcgtcccaa acatatttgg ggcgattttt tattacaaaa
      661 aatctaaaaa ttatttcaat aaggaggaaa aaacaatgat taaagttgct ttaaaagatg
      721 gctcaataaa agaatttgaa aatgctattt ctgttatgga tgtagctaaa tccattagtg
      781 aaggattagc tagaaatgtg gtagcagcgt ctgtgaacgg agaggttgta ggtctggacc
      841 acattataga tactgattgt gacttgaatt tatttaagtt tgaagataaa gaaggtaagg
      901 aagtttttag acatacatca gcgcatatat tagctcaagc tataaaaaga ctttacccag
      961 aagcaaagct tgctatagga ccaagtatag aaaatggatt ctactatgat atagatttag
     1021 accatagatt agttccagag gacctagaga aaatagaagc tgaaatgaaa aaaatagcta
     1081 aagaagattt aaaaatagaa agatttgaac ttcctagaaa tgaagcttta gagcttatga
     1141 aagaacaagg agaagactat aaggtagaac ttatatctga tttacctgaa agtgaaataa
     1201 tatctttcta caagcaaggt gattttactg atttatgtag aggaccacat ttaccatcta
     1261 ctaaaaaggt aaaagctgtt aaattacaaa gtgtagcagg tgcatattgg cgtggtgacg
     1321 aaaataataa gatgcttcaa aggatatatg gaacttcttt tgagaaaaac aaagacttag
     1381 aagagtactt acatttacta gaagaagcta aaaagagaga ccacagaaaa ttaggtaaag
     1441 aattaggatt atttatgata cctgaagaag gtccaggatt ccctatgttt ttaccaaaag
     1501 gtatggaact taaaaatgaa ttattaaaat tctggagaga aatacacaga aaagctggat
     1561 atattgagat agaatctcca atcatattaa atagaaaatt atgggagact tcaggacact
     1621 ggtatcatta caaagaaaat atgtatacag ttaaaataga tgatgaggat tatgctataa
     1681 aacctatgaa ctgtcctggt ggattaattt attataactc tcaactacat tcatatagag
     1741 atttcccaat gagagttgca gagcttggta gagttcatag acatgagtta tctggtgcat
     1801 tacaaggatt aatgagagtt agagcattta ctcaagacga ttcacatata ttcatgttac
     1861 cagagcaaat taaggacgaa ataaaaggag tagctaactt aatagatggt atatacaaaa
     1921 cttttggatt tgaatataat ttagaattat ctacaagacc agagaactct atgggaagcg
     1981 acgaagagtg ggaagcagca gaaaatggat taagagaagc tttagaagag ttaggtctac
     2041 catatactat taatgagggt gatggagcat tctatggtcc taagatagac ttccatctaa
     2101 aagattgttt aggaagaact tggcaatgtg gtactatcca attagatatg caacttccaa
     2161 gacaatttga taatacttat attggtcaag atggtgaaaa gcatagacca gttatgattc
     2221 atagggttgc ttttggtagt atagaaagat ttataggtat attaatagag cattatgctg
     2281 gtaaattccc agtttggtta tctccaactc aagttaagat acttcctata tctgataaat
     2341 ttatggatta tgcaaatgaa gttaagaaag agttatttga taagggtata agagttgaat
     2401 tagatgatag agctgaaaaa attggattta agataagaga agctcagctt gaaaaagtgc
     2461 catacatgct aatagtaggt gaaaaagaag tagctgataa taatgtttct gttagatcaa
     2521 gagataaagg tgaaataggt agtattaaat tagatgaatt tatagctagt atttcaaaag
     2581 aaattgaatc aagagaaagt attattcaag actaatatat attatattag tagctaagat
     2641 attgttatat aagataagtt taatcaatat gttgatatgt tgatgcatag tgattaaatt
     2701 tatgaaaaga tgagtataat tagaggtaca gttaatcata tttttatgat taatgtacct
     2761 ctagtttttt gtatggtaga tttattaata aatatatcat agaagtgttt tgaacatgga
     2821 aatatttatg tgcattcttt aaataaaagt ttatttttga gtgataatta agtgcttgtt
     2881 ggtaaggtta tggttgtaaa aatcataact ttattttcat atttgttcca ttttcataaa
     2941 aattattatc cctttaagaa aatttcttaa tcctcttgaa atatttcctt tttagtctaa
     3001 agttaaattt ctttcttcaa aatgaatatt taaatgaact aaaatttaag tacattttct
     3061 aatcttatga gtctattttt catagataat tgccctataa tagaagaatc tatgttggtg
     3121 ctatgtggtg acaataacag cattgtcagt gattaattaa tgctttataa atgattaatt
     3181 agtgttttat gttatttttg gacttatcct ctatacatag attaatttat ttaactttag
     3241 atagagagag aatgtcaagt acatacacag acattagagt ttaagaaagt gtttatggag
     3301 caagaacttt taaaagaggt agtgacttag tttaatttca agaaatgata aatagaaaag
     3361 aggaaaaaga gaggtgttga aatgatagaa aaagtagaag aaaaatctaa gattattaaa
     3421 acatcaaaag aatataagcg aactataatt gaagaaaaag ataaagaatg gaccaaaaaa
     3481 ttaaatgata tacttagtag aagtagtttt tctaatgatg aattagataa aatcaaggca
     3541 ttaattccaa aagagatttt gactaatgaa aatgttggag aagttgtgac tgaagatgga
     3601 tatgctaagc ctgagtatga tgaggtattt aaatcattgt tcactttaaa taatgaatat
     3661 gatttacttg taaattttat aaatgatatc ctaaaagatg ctccatatgc taacaggaat
     3721 atcaaaccgt tcactcaaat aaagagaata attagagttg aaactgaccc aacaattaat
     3781 tacattggag agaaaagacc tagacttgat attttggctg aagatgaaga aaataatcat
     3841 ataaatattg agatgcaaag agcttttgag aacgattatt tggaaagagc tgaatattat
     3901 cttagtcgtg tacatagtag aaagttagaa gaaggtaaag agtataaaga aattggaaaa
     3961 actattggaa tacatatact aaatcatgta aaatataatc acatagaaga ttatgtaaat
     4021 tgcctgagat taacaatgga cgggcatcca gatatttatt ctagtaaaac tgcattatat
     4081 tttatagagc ttccaaaaat tcataaatct gactatatag taaatagaat tatgctatgg
     4141 ggaaaactta ttagtaatcc ttctaactta gatgtaagag ttatagctaa gaatgattct
     4201 attattaaaa aagcacttga tagattaaaa gaattaggta gcaatgaaga atatttatta
     4261 aatctgaaaa gaggtgctta tatcatgaat aaaagtagaa attttaaaga agagattgaa
     4321 agagagacag caattagagt tgcaaaagaa aaagattata aaataattat aatgttgaaa
     4381 aaaatggttt taaattagat gacatattaa ataaatttaa tgattttgac ttaagtgaag
     4441 atgagataaa agaagtatat gaaaataatt gatgataaat aaaaagtgaa cttatataag
     4501 tttgctgaat cggagtctgg aaatatttat gtgtattttt taatgaatga aaatttattt
     4561 taaaaacaat aatttagaag tacagttaat tatattttta tgatactgta cttctagttt
     4621 tttctattgt agatttatta tttactaata aatctacaat agaaatgctt ttgttgtaag
     4681 aatcatttta tctaatgatt gttttttata atagttaaat ttccatttgt agtgtttaaa
     4741 tataaatcta taacagcatt tctataaatg ttataaatca ctataatgat tcaactcaaa
     4801 gttactgctt aaagaagcag agattttatc aaggtatatc atggaaaaaa tattttattg
     4861 taatatttat aagattttat tatggaaata atgtaaaaac tttataaata atatatttta
     4921 tacctagtta tagataaatt tatatagtta ttattaaaaa aagcaataaa aagtttaatt
     4981 caatttagca aatttagtga tataattaaa aaagaaaaga aatatggact tatttggaat
     5041 aattttgaca atctatttac tacacgtgta gagtcgtata taattaaatt atacataaaa
     5101 tataaaaaaa taatttagta atacgttagg agaaagtatt atgataaagt caagcttatt
     5161 ttggaatatt ttcattgcga tatcctttat gatagaatgg tttctttgta agaaaatgct
     5221 agattataca agtgagaaaa ggatttctaa caaaaaaata aacttttgtg tggtaggtat
     5281 tattgttttt gctgacataa tatatttttt tgatgtacct ccaaatataa tagtaattat
     5341 atctatgata attactattg cattttataa aatctcatat gatgtggggt ttataaagtc
     5401 tgtattaata tccttaattt attggatgtt actaatcgcc acagatgctt tgagtatatc
     5461 tttaacagtt tggcttaatt ctataaatga catgagtagt atggggacgg gagatatata
     5521 cagaattgag tctataatat tgggaaagat acttttgatt gtgtctttgc ttttatatag
     5581 agccttaaag ataaaactta atatagaaat aaataaaagg acattatttt atatagttat
     5641 tcctatagtc gctaatatag catctttttt tgtaattttt gaatacatat ttaatccagg
     5701 gtctggtagc ttaatacata atttccaatt cgttatgatt tctgttgtat tgcttatatc
     5761 aagtatcact ttagttttaa ttgctaaaaa attacagcaa tataatactt tagttgtaga
     5821 aaacaatatg attaaaaata ctttgaagta tgaaaatgag tattatgaag atatagaaaa
     5881 gaaatattta aaaactagat tactaagtca tgatatgaaa aatcacatat tgtgtataaa
     5941 tgctatgatt aaaaaaggta ttgatgttac ttcttattta aataatttgc aggtagaaat
     6001 tcagagtaat gacttgttat ttaatactgg taattttata ttagatgcta tattaagtga
     6061 aaagaaagag gtttgtgata agaatgatat agaactaaaa ataggaataa attttagttg
     6121 ttgtgaagct gttgaattag tggatatatg tcatatattt tcaaatattt tagacaatgc
     6181 aattgaggca tgtaataaaa ttgatagtgg aaatagagtt atttgtgtta aaggtgatgt
     6241 tatgcaaaat ttttatttaa taagagttga aaatactaag ataaataaga ttattactaa
     6301 aaatggagat attttgacag acaaaaaagg ttctcttcat ggacttggaa taaaaagtgt
     6361 aaaaaactct gtaaataagt atggtggtaa tgttgtaatt gaatatgatg ataaaaaatt
     6421 tgtagttaaa attgctattc cacttagaaa tgtgaagaaa gcagttaatc atgtgattta
     6481 aatgtatata aatttgatgt gtagaa
//
LOCUS       DAEORM030000108         6473 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.114, whole genome shotgun sequence.
ACCESSION   DAEORM030000108 DAEORM030000000
VERSION     DAEORM030000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6473)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6473)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 6473)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6473
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.114"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            352..1296
                     /locus_tag="KRH23_003678"
     CDS             352..1296
                     /locus_tag="KRH23_003678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP phosphoribosyltransferase regulatory
                     subunit"
                     /protein_id="HHS5226942.1"
                     /translation="MKFLRIEDEVIYSKKRYKLKREIDKLFLDEEYFQIEPQLFEEYD
                     EFTTINNKIPEESMVKVVNGKVMVLRADITTSIIKSLVPRWEDGLKLKLFYNSSIYKN
                     KNTVGIKEIRQIGCEYLGEASVEADREVVKLALKILEKYNNNFILEVGSSKYIHGLLE
                     ELNLNKNCENQIKNLLYTKNTHELKVYIEELKIKREVKELLSNILSLQGNLYNVIEKS
                     NKFYCNNKMKQALEELKQVNNLIEECNFLDKARFDLSMITMLDYYEGIMFRGYYPNSY
                     KEILSGGRYDSLTKEYGKKIPAIGFTLSVDELMKYVYK"
     gene            1318..1944
                     /gene="hisG"
                     /locus_tag="KRH23_003679"
     CDS             1318..1944
                     /gene="hisG"
                     /locus_tag="KRH23_003679"
                     /EC_number="2.4.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003879 - ATP phosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP phosphoribosyltransferase"
                     /protein_id="HHS5226943.1"
                     /translation="MDYLTIALAKGRIEGESFKKFKKMGLGDSIDTDTRKLIFKDEEN
                     KIIYIHVKPSDVVTYVEKGVADLGIAGKDTILENETDVYEIYDLGFGKCKFAVAGLKG
                     DSIYREDEYLKVATKYPNIAKKYFKEKGQKIEIIKLNGSVELAPIVGLSDVIVDIVET
                     GNTLKANGLEILEDICNISARIISNRASYRFKYEQIQNIIRLFEELDN"
     gene            1978..3027
                     /gene="hisC"
                     /locus_tag="KRH23_003680"
     CDS             1978..3027
                     /gene="hisC"
                     /locus_tag="KRH23_003680"
                     /EC_number="2.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004400 - histidinol-phosphate
                     transaminase activity [Evidence IEA];
                     GO_process: GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphate transaminase"
                     /protein_id="HHS5226944.1"
                     /translation="MREKESIRELKGYEPNHVNCKVKLDANEGSKRLFKYLIKEISDS
                     DIDLNLYPEDSYSDLKESIIDYINISGVNKKNLLVGNGSSEIIDLIIHTFVDKDEVIL
                     SFSPSFSMYSIYSQINGSKFIGVESDENLVINIDNVIEKVKENNPKIVIVCNPNNPTG
                     TILKREEIIKLLDSTNSLVVLDEAYMDFGEESMLSDVFKYDNLIVLRTLSKAFGLAGI
                     RTGYMLSNSSLINSVEKVRPPYNLNSLSDFIATRALRNKDVVKAYIKEVKEEREVLYE
                     EMIGMGIKAYKSQANFILFYSEIENLSQKLIDRGVLIRKFGGKLENYYRVTIGDKEEN
                     SMFVGAIRDILKKEK"
     gene            3030..3608
                     /gene="hisB"
                     /locus_tag="KRH23_003681"
     CDS             3030..3608
                     /gene="hisB"
                     /locus_tag="KRH23_003681"
                     /EC_number="4.2.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004424 - imidazoleglycerol-phosphate
                     dehydratase activity [Evidence IEA];
                     GO_process: GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="imidazoleglycerol-phosphate dehydratase HisB"
                     /protein_id="HHS5226945.1"
                     /translation="MRIWKVERNTLETQILVELNIDGSGKAEIDTGIGFLDHMLTLMS
                     FHGKFDLKVICKGDTYVDDHHSVEDIGIAIGEAFKNALGDKKGIRRYSNIYIPMDESL
                     SMVAIDISNRPYLVFNAKFDTQMIGSMSTQCFKEFFRAFVNESRVTLHINLLYGENDH
                     HKIESIFKAFARALKEGSEIVSNEIASSKGVL"
     gene            3610..4215
                     /gene="hisH"
                     /locus_tag="KRH23_003682"
     CDS             3610..4215
                     /gene="hisH"
                     /locus_tag="KRH23_003682"
                     /EC_number="4.3.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000107 - imidazoleglycerol-phosphate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="imidazole glycerol phosphate synthase subunit
                     HisH"
                     /protein_id="HHS5226946.1"
                     /translation="MNIIVDYGLGNIDSVSRGFRKAGIETKISSDIDEIKQADSLILP
                     GVGAFRDSISALDKLGLIPIIKEHVSKGKFMIGICLGMQLLYEKSYEYGEYEGLGLIK
                     GSIDKLDISLKVPHMGWNNLKFNKANDDILKYINEDDYVYFVHSYYANSSNEELIAFS
                     EYEKKIPAIVRKGNVYGIQFHPEKSGEVGLNILRAYGEMIK"
     gene            4212..4934
                     /gene="hisA"
                     /locus_tag="KRH23_003683"
     CDS             4212..4934
                     /gene="hisA"
                     /locus_tag="KRH23_003683"
                     /EC_number="5.3.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003949 -
                     1-(5-phosphoribosyl)-5-[(5-
                     phosphoribosylamino)methylideneamino]imidazole-4-
                     carboxamide isomerase activity [Evidence IEA];
                     GO_process: GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-(5-phosphoribosyl)-5-[(5-
                     phosphoribosylamino)methylideneamino]imidazole-4-
                     carboxamide isomerase"
                     /protein_id="HHS5226947.1"
                     /translation="MIIFPAIDIKDNKCVRLTQGEFDKVNVYYDNPLEVAYKWKNEGA
                     EYIHIVDLNGARSEFGVNTKIIEDIANNIDIPIQVGGGVRDKEKVKSLINAGVTRVIL
                     GSIAIENLNLVEELVNEYKEKIVVSIDAKDGKVAVRGWEVVSNVDSLTLCKQLEKIGV
                     QTIVYTDISKDGMLQGPNFDIYERIAKETSLNVIASGGVTSIEDVKRLKAMNLYGAII
                     GKALYDKKIDFKEAQQLCLLGE"
     gene            4916..5674
                     /gene="hisF"
                     /locus_tag="KRH23_003684"
     CDS             4916..5674
                     /gene="hisF"
                     /locus_tag="KRH23_003684"
                     /EC_number="4.3.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000107 - imidazoleglycerol-phosphate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="imidazole glycerol phosphate synthase subunit
                     HisF"
                     /protein_id="HHS5226948.1"
                     /translation="MLTRRIIPCLDVRNGRVVKGKKFKDIVDVDSPEVLGKFYSDCGA
                     DELVFYDITASNEERKTSLEFVTKVAENINIPFCVGGGVNKLEDFTDILRKGADKVSI
                     NSSAVKNPELIREASLKFGAQCVVLSIDAKKNEEGSWSVYVKGGREKTNLDAIEWAVK
                     GVELGAGEIVVNSMDEDGMKNGYDIELLSKITSLVNVPVIASGGAGKKEDFYEAVNKS
                     NVDGILAASVFHFGEIKINDLKKYLKDMGVEVRL"
     gene            5702..6370
                     /gene="hisIE"
                     /locus_tag="KRH23_003685"
     CDS             5702..6370
                     /gene="hisIE"
                     /locus_tag="KRH23_003685"
                     /EC_number="3.5.4.19"
                     /EC_number="3.6.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004635 - phosphoribosyl-AMP
                     cyclohydrolase activity [Evidence IEA];
                     GO_function: GO:0004636 - phosphoribosyl-ATP diphosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional phosphoribosyl-AMP
                     cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE"
                     /protein_id="HHS5226949.1"
                     /translation="MDNKCNNVYSDEVEKFIRSIKFDDKGLVPVVVQEVVSKDVLMLA
                     YMNKDAIKKTLKDKVACYFSRSRQELWVKGETSGNTQKVVKMSYDCDVDTILLFVEQT
                     GVACHTGNYSCFYRDLFDDSSKMELEVQTNILKELYDLINERKNNPVEGSYTNYLFEK
                     GIDKILKKVGEESSEVIIASKNTDKSELIYEISDLVYHTLVLMIEKGVEIDEIKKELL
                     KRRK"
BASE COUNT         2651 a          543 c         1260 g         2019 t
ORIGIN      
        1 tttaaataac tattgccaat ttttgaaaaa tatattatta ttaatagtaa caaaaaactg
       61 taaatttaga atattaataa aaattatttg ggaggaaatt atcatggtga gattaaatat
      121 agtaaaatta aatacaaaat taaatcatca ccatcatcat agattaaagg gattgtaata
      181 tgaaattaat tcatagacac aagccctgtt tttagtgtaa ttggtcttgt atctatgatg
      241 ggaagtaatt ttaagagaaa attatagcca tataggtata aagcctatgt ggctttttta
      301 ttgttttaaa tttgcaaata taagagtaaa tttaatgaag agggtgagaa tgtgaaattt
      361 ttgaggattg aagatgaggt tatttattct aaaaaaagat ataaattaaa aagggaaata
      421 gataaacttt ttttggatga agaatatttt caaatagaac cacaattatt tgaagaatat
      481 gatgaattta caactataaa taataaaatt ccagaagaat ctatggtaaa ggttgtaaat
      541 ggaaaagtaa tggtacttag agctgatata actacaagta taataaaaag ccttgtacca
      601 agatgggaag atggtttaaa gcttaagctt ttttataatt catcaatata taaaaataaa
      661 aatacagttg gaataaaaga gataagacaa ataggttgtg agtatctagg agaagcctct
      721 gtagaagcag atagagaagt agtgaaatta gctcttaaga tacttgaaaa atacaataat
      781 aattttattc tagaggttgg gagtagcaag tatattcatg gtttgttaga agaattaaat
      841 ttaaataaga attgtgaaaa tcaaattaaa aatttactat atacaaagaa cactcatgaa
      901 ctaaaagtat atattgaaga attaaaaatt aagcgtgaag taaaagagtt attatcaaat
      961 attttaagtt tacaagggaa tttatataat gttattgaaa aatcaaacaa gttctattgt
     1021 aataataaga tgaagcaagc tcttgaagaa ttaaagcaag taaataactt gattgaggaa
     1081 tgtaattttt tagataaggc tagatttgat ttatcaatga ttactatgct tgactattat
     1141 gaaggaatta tgtttagagg atactaccca aactcatata aagaaattct tagtggtgga
     1201 agatatgatt ctttaactaa agagtatgga aaaaaaattc cagccattgg atttacacta
     1261 agtgttgatg agttaatgaa gtatgtatat aagtaaagtt tagaaggagg gattgttttg
     1321 gattatttga ctatagcact agcaaaagga cgaattgaag gggaatcatt taaaaaattt
     1381 aaaaaaatgg gtctaggaga tagtatagac acagatacga gaaaactaat ttttaaagat
     1441 gaagaaaata aaattatata tatacatgta aagccatcag atgtagttac atatgttgaa
     1501 aaaggagtcg ctgacctcgg tatagcaggt aaagatacta ttttagagaa tgagacagat
     1561 gtatatgaaa tatatgattt aggttttgga aaatgtaaat ttgctgtagc aggattaaag
     1621 ggagatagca tatatagaga agatgaatat ttaaaagtgg caacaaagta tcccaatata
     1681 gcaaaaaagt attttaaaga gaaaggtcaa aaaattgaaa taataaaatt aaatggttct
     1741 gtagaactag ctccaatagt agggttgtca gatgtaattg tagatatagt tgagactggc
     1801 aatacactta aagcaaatgg tcttgaaata ttagaagaca tatgtaatat aagtgctaga
     1861 attatatcaa atagagctag ctatagattt aaatatgaac aaattcagaa tataattcgt
     1921 ttatttgaag aacttgataa ttaaaatata attgagcttt ataaggaggg atttaagttg
     1981 agagaaaaag aaagcataag agagttaaag ggatatgaac caaatcatgt aaactgtaaa
     2041 gtaaaacttg atgcaaatga aggaagtaag aggttgttta aataccttat taaagaaatt
     2101 tcagatagtg atatagattt aaatttatat cctgaagatt cttatagtga tttgaaagaa
     2161 tctataatag attacataaa tatttctgga gtaaataaga aaaatcttct agtaggaaac
     2221 ggttcaagtg aaataattga tttaataata catacttttg tagataaaga cgaagtaata
     2281 ttgagtttct ctccaagttt tagtatgtat tctatatata gtcagataaa tgggtctaaa
     2341 tttataggtg ttgaaagtga tgaaaattta gttataaata tagataatgt gattgaaaaa
     2401 gtaaaggaga ataatcctaa aatagtaatt gtatgtaatc ctaataatcc aactggaaca
     2461 atattaaaga gggaagagat aataaagctt ttagattcaa ctaatagtct agtggtttta
     2521 gatgaagcat atatggattt tggagaagaa agcatgttaa gtgatgtttt taagtatgat
     2581 aatctaatag ttcttagaac tttatcaaag gcatttggat tggctggaat aagaacagga
     2641 tatatgttat ctaatagtag tttaataaat tctgttgaga aagtaagacc tccatataat
     2701 ttaaattcat tatcagactt tattgctaca agagcactta gaaataaaga tgtggtaaaa
     2761 gcttatataa aggaagtaaa agaggaaaga gaagttttat atgaagaaat gattggtatg
     2821 ggaattaaag catacaaatc acaagcaaat tttatattat tttattctga aatcgaaaat
     2881 ttatcacaaa aacttattga tagaggtgtt ttaataagaa aatttggtgg aaagttagaa
     2941 aattattaca gagttacaat tggtgataaa gaagaaaatt ctatgtttgt tggagctata
     3001 agagatattt tgaaaaagga gaaataggta tgagaatttg gaaggtagaa agaaatactc
     3061 ttgaaacaca gattttagta gaattaaata ttgatggttc tggtaaagct gaaatagata
     3121 ctggaatagg atttttagac catatgctta ccttaatgtc atttcatggc aagttcgatt
     3181 taaaagtgat ttgtaagggt gatacatatg tagatgacca ccatagtgta gaagatatag
     3241 gtatagctat aggtgaagca tttaaaaatg ctctaggtga caaaaaagga atacgaagat
     3301 attctaatat ctatatacct atggatgaat ctctatcaat ggtagcaata gatataagca
     3361 atagacctta tcttgtattt aatgctaaat ttgataccca aatgattggt agtatgagta
     3421 ctcaatgctt taaagaattt tttagagctt ttgtaaatga atcgagagta acattacata
     3481 tcaatctctt atatggggaa aatgaccatc ataagataga aagtattttt aaagcatttg
     3541 caagagcttt aaaagagggt agtgaaatag tttctaatga gatagcatct tcaaaggggg
     3601 ttttgtagaa tgaatataat agtagactat ggtcttggaa atatagattc tgtgtctagg
     3661 ggttttagaa aagctggaat agaaactaaa atttctagtg atatagatga aataaaacag
     3721 gcagattcac ttatacttcc aggtgttgga gcttttagag attctataag tgccttagat
     3781 aaactaggat tgataccaat aataaaggag catgtttcta agggtaaatt tatgataggt
     3841 atatgtctag gaatgcaatt actttatgaa aaaagttatg agtatggaga atatgaagga
     3901 ttaggactta taaaaggaag tattgataaa ctggatataa gtttaaaagt gccacatatg
     3961 ggatggaata atctaaaatt taataaggca aatgatgata tacttaaata tataaatgaa
     4021 gatgattatg tatacttcgt tcactcatat tatgcaaatt catcaaatga agaactaatt
     4081 gcattttcag aatatgaaaa gaaaatccct gctattgtta gaaaaggcaa tgtatatggt
     4141 atacaatttc atcctgaaaa aagtggagaa gtagggttaa atatattaag agcatatggg
     4201 gagatgataa aatgataata tttccagcaa tagatataaa agataataag tgtgtaagac
     4261 tcacacaagg agaatttgac aaagtaaatg tatattatga taatccatta gaagtagcat
     4321 ataaatggaa aaatgaagga gcagaatata tacatatagt agatttaaat ggtgctagaa
     4381 gtgaatttgg tgtaaataca aaaataattg aggacatagc aaacaatata gatataccta
     4441 ttcaagttgg cggtggagtt agggataagg aaaaagtcaa aagtttaata aatgctggtg
     4501 ttactagagt aatattaggt agtatagcga ttgaaaattt gaatttagtt gaagaattgg
     4561 tcaatgaata taaagagaaa attgtagttt ctatagatgc taaagatgga aaagtagcag
     4621 ttaggggatg ggaagttgta agcaatgtag actcattaac attatgtaaa caacttgaaa
     4681 agataggtgt acaaactatt gtttatacag atatatcaaa agatgggatg ttgcaaggtc
     4741 caaattttga catatatgaa agaatagcaa aggaaacatc actaaatgtt attgcttctg
     4801 gaggtgtaac ttctatagaa gacgtaaaaa gactaaaagc tatgaactta tatggtgcaa
     4861 taataggtaa agcgctttat gataaaaaga tagactttaa ggaggcacaa caattatgct
     4921 tactaggaga ataatacctt gtctagatgt gagaaatgga agagtcgtaa agggaaaaaa
     4981 atttaaagat atagtagatg ttgatagtcc agaagtactt ggaaaatttt atagtgattg
     5041 tggtgcagat gaacttgtat tctatgatat aactgcatca aatgaagaga gaaagacatc
     5101 tttagaattt gtgacaaaag ttgcagaaaa tataaatata ccattttgtg ttggtggagg
     5161 agtaaataaa ttagaagatt tcactgatat tttaagaaaa ggtgctgata aagtttctat
     5221 aaattcatca gcagtcaaaa atcctgaatt aataagggaa gcttcattaa aatttggagc
     5281 acaatgtgtt gttttatcga tagatgcaaa gaaaaatgaa gagggttcat ggagcgtata
     5341 cgtaaaaggt ggaagagaaa aaactaatct ggatgcaatt gaatgggctg ttaaaggtgt
     5401 agaacttgga gcaggagaaa tcgttgtaaa tagtatggat gaagatggaa tgaaaaatgg
     5461 atatgatata gaattattat caaagataac ttctttagta aatgtacctg ttatagcatc
     5521 tggaggcgct ggaaaaaagg aagattttta tgaggcggtt aataaatcca atgtagatgg
     5581 aattttagca gcatctgttt ttcattttgg cgagataaaa ataaacgatt taaagaaata
     5641 tttaaaagac atgggtgtag aagtaagatt ataagttaaa tactaaaagg agattagaaa
     5701 tatggataat aagtgtaaca atgtatacag tgatgaagta gagaaattta taagaagtat
     5761 aaagtttgat gataaagggt tagtccctgt tgttgttcaa gaggtagtta gcaaagatgt
     5821 actgatgtta gcatatatga ataaagatgc tataaagaaa accttaaaag ataaagtagc
     5881 ttgctatttt agtagaagta gacaagaact ttgggttaaa ggtgagacat ctggtaatac
     5941 tcaaaaagta gttaagatgt cttatgattg tgatgtagat actatactac tttttgttga
     6001 acaaactggt gtagcttgtc atacaggcaa ttattcttgt ttttacagag acttgtttga
     6061 tgatagttca aaaatggagc ttgaagtaca aacaaatata ttgaaagaat tatatgattt
     6121 aatcaatgaa agaaaaaata atccagttga aggttcttat actaattatc tttttgaaaa
     6181 aggaatagat aagattctta aaaaagtagg tgaagagagt agtgaggtaa ttatagcatc
     6241 aaaaaatacc gataaaagtg aacttattta cgaaattagc gatttagtat atcatacatt
     6301 ggttttaatg atagaaaaag gtgttgaaat tgatgaaata aaaaaagaat tacttaaaag
     6361 aagaaaatag aataagatag attaatgggt aataagaaaa tataccactt ttaataaaaa
     6421 gtggtatatt ttttatttta tattttaatt tatagaataa tatttaaatt act
//
LOCUS       DAEORM030000109         6219 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.115, whole genome shotgun sequence.
ACCESSION   DAEORM030000109 DAEORM030000000
VERSION     DAEORM030000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6219)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6219)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 6219)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6219
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.115"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            170..1192
                     /locus_tag="KRH23_003686"
     CDS             170..1192
                     /locus_tag="KRH23_003686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HHS5226950.1"
                     /translation="MKNLLEIQKKLIPQAIELMERRYSILRQISLSEPIGRRTLSNVL
                     EISERIIRSETEFLKEQGLIDVAVSGMTITKEGSDLLDKLKDIMSDIMGLSKLQDRVR
                     EKLGIKRVILVPGSCDENGSLLKDVTRYGCEYFLGILKDGDIVSITGGSTMLEFSNVI
                     KTDKRYPNSTIVPARGSMGTDVEMQSNNIVASISKKLHSNCKLLHIPDELDESAMKTL
                     SQVPEIKTTLEYIKRTDILVFSIGRADVMAKRRKLPEDKVDEILSKNAVGEAFGYYFN
                     KDGEIVYKLNTVGIDLETVKQVKETIAIFAGTEKVEALLAISNMHKNMVLVTDEESAY
                     KILSLL"
     gene            1252..2259
                     /gene="gap"
                     /locus_tag="KRH23_003687"
     CDS             1252..2259
                     /gene="gap"
                     /locus_tag="KRH23_003687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HHS5226951.1"
                     /translation="MVKVAINGFGRIGRLALRKMMEQQDKFEVVAINDLTDAKMLAHL
                     FKYDTAQGRFNGEIEVKEGAFVVNGKEIKVTAERNPADLPWAELGVDIVLECTGFFTS
                     KDKAEAHIQAGAKKVVISAPATGDLKTIVFNTNSDILDGSETVISGASCTTNCLAPMA
                     KVLNDKYGIEKGLMTTIHAYTNDQNTLDGPHPKGDLRRARAAAGNIVPNTTGAAKAIG
                     LVIPSLKGKLDGAAQRVPVVTGSITELVCTLGKNVTVEEINAAMKEASNESFGYTEEM
                     LVSSDIIGISYGSLFDATQTKVMEVDGKQLVKVVSWYDNEMSYTSQLIRTLGYFAQLA
                     K"
     gene            2481..3683
                     /locus_tag="KRH23_003688"
     CDS             2481..3683
                     /locus_tag="KRH23_003688"
                     /EC_number="2.7.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004618 - phosphoglycerate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HHS5226952.1"
                     /translation="MSMLNKKTIEDIDVCGKKVLVRCDFNVPLQDGVITDENRLNGAL
                     PTIQYLISKGAKVILCSHLGKPKGEAKPELSLAPVAKRLSEMLGKEVVFAADDNVVGE
                     NAKKATEKMENGDVVLLENTRYRKEETKNEENFSKELASLAEIFVNDAFGTAHRAHCS
                     TVGAGEFLQERVCGYLIQKELKFLGEAVANPVRPFTAILGGAKVSDKLAVINELLEKV
                     DNLIIGGGMAYTFLKAQGYEVGTSLLEIDKVEYAKEMMEKAKNKGVNLLLPVDVVMAD
                     HFAPDATPIVTEDANVKEDYMGLDMGPKTIANFVKTIKESKTVVWNGPMGVFEFENFA
                     NGTLSVARAMAELTDATTVIGGGDSAAAVNQLGFGDKMTHVSTGGGASLEFLEGKELP
                     GIAALDNK"
     gene            3709..4452
                     /gene="tpiA"
                     /locus_tag="KRH23_003689"
     CDS             3709..4452
                     /gene="tpiA"
                     /locus_tag="KRH23_003689"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004807 - triose-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HHS5226953.1"
                     /translation="MRKPIIAGNWKMHKTIKEALEFVNEVKDKVNSDKVEAVICAPFT
                     LLKDLKEATKGTNIKIGAQNMHFEEKGAFTGEVSPLMLKEIDMDYVVIGHSERRQYFN
                     ETDETVNKKVLKALEVGIDPILCVGETLEQREAGKTKDVCKVQVEKALENVLKDDLAK
                     VVVAYEPIWAIGTGKTATAEDANDVISYIREVIKGLYGELANEVRIQYGGSVKPSNVA
                     EIMGQSDIDGALVGGASLASNDYLDLVNF"
     gene            4464..5993
                     /gene="gpmI"
                     /locus_tag="KRH23_003690"
     CDS             4464..5993
                     /gene="gpmI"
                     /locus_tag="KRH23_003690"
                     /EC_number="5.4.2.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004619 - phosphoglycerate mutase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-independent
                     phosphoglycerate mutase"
                     /protein_id="HHS5226954.1"
                     /translation="MKKPVALIIMDGFGYNKDVKGNAIAESKTPNLDRTKKEYPNTLI
                     NASGLDVGLPDGQMGNSEVGHTNIGAGRIVYQDLTRITKSIKDGDFFTNKVLCEAMDN
                     AKENSLHVMGLLSDGGVHSHIDHLKAIIKMAKDKGVQKVYVHAFTDGRDTDPQSALEY
                     AKEVQASMDEIGVGEFATVSGRYYAMDRDKRWERVELAYNAMVRGIGEKANSIEEAIQ
                     NSYDDGKNDEFIMPTVIMKDDKPVGSIKENDSIIFFNFRPDRARQITRALVCEEFDEF
                     KREDIKNFFVCLTEYDITIENVHIAFGPQSLANTLGEYLAKNGKTQLRAAETEKYAHV
                     TFFFNGGVEEPNKGEERLLIPSPKVATYDLKPEMSAYELTDKALDKLGEDKFDFIVLN
                     FANPDMVGHTGSIEAAIKAVETVDTCVGKLIDKIVELGGSAIITADHGNAEYMLDPET
                     GKTVTAHSINPVPFIVVGQEYESAKLLDGGRLSDIAPTILDMMKLEKPEEMTGHSLIS
                     K"
BASE COUNT         2484 a          725 c         1249 g         1761 t
ORIGIN      
        1 gtgatttgaa aatggtggag aaatatttta taaaataaaa aaataaaaaa gtttttgaaa
       61 aactattgaa atctatacgc aaatcctata aaataaaaat atcttgtggg acttaaataa
      121 acactaggga caaaaaaagt cccgaaagga aagcaataag gagtatgtta tgaagaactt
      181 attagaaatt caaaagaaat tgattccaca ggcaattgaa cttatggaaa gaagatactc
      241 tattttaaga caaatatctt taagtgaacc aataggtagg agaacattat caaatgtatt
      301 agagattagt gaaagaataa tcaggtcaga aactgagttt ttaaaagaac aaggacttat
      361 agacgtagct gtatctggga tgactatcac taaagaaggt tctgatttgt tagataaact
      421 taaggacatc atgagtgaca tcatgggatt gtctaagtta caagatagag tcagagaaaa
      481 gcttggaata aaaagggtaa tattagttcc tggaagctgt gatgaaaatg gaagtttact
      541 aaaagatgta actagatatg gatgcgaata tttcttaggc attttaaaag atggagatat
      601 cgtttcaata acaggaggaa gcactatgtt ggagttttca aacgttatta aaactgataa
      661 gagatatcca aactctacaa tagttccagc tagaggaagt atgggaactg atgtagagat
      721 gcaatctaac aatatagttg cttcaataag taagaaatta cattctaatt gcaaactttt
      781 acatatacca gatgagttgg atgaaagtgc aatgaaaact cttagccaag tgccagagat
      841 taagacaact ttggagtata ttaaaagaac agacatttta gtttttagta taggtagagc
      901 agatgtcatg gcaaagagaa gaaaacttcc agaagacaag gttgatgaga tattatctaa
      961 aaatgcagtt ggagaagcat ttggatatta tttcaacaaa gatggagaaa tagtttacaa
     1021 actgaacact gttggaattg atttagaaac agttaaacaa gtaaaagaaa ctattgcaat
     1081 ctttgcaggg actgaaaaag tagaagcctt attagctata tcaaatatgc ataaaaacat
     1141 ggttcttgta acagatgaag aaagtgctta taagatattg tcattattat aaaagtcaag
     1201 acctagcaca gagctagaaa acatacattt actttatagg aggtagcgaa aatggttaaa
     1261 gtagctataa atggatttgg aagaatagga agattagcat taagaaaaat gatggagcaa
     1321 caagataagt tcgaagttgt tgcaataaac gacttaacag acgctaaaat gttagctcat
     1381 ttatttaaat atgatacagc tcaaggaaga tttaacggag aaatagaagt taaagaaggt
     1441 gcttttgtag taaacggaaa agaaataaaa gtaacagcag aaagaaatcc tgctgaccta
     1501 ccatgggctg aattaggagt agatatagta ttagaatgta caggattctt tacatctaaa
     1561 gataaagctg aagctcatat acaagcaggg gctaagaaag ttgttatatc tgcaccagct
     1621 actggagatt taaaaacaat agtattcaac acaaacagtg acatattaga tggttctgaa
     1681 acagttatat caggagcttc ttgtactact aactgtttag ctccaatggc taaagtatta
     1741 aatgataaat acggtataga aaaaggatta atgactacta tacatgcata cactaatgac
     1801 caaaatactt tagatggtcc tcatccaaaa ggtgatttaa gaagagctag agctgctgct
     1861 ggaaacatag ttccaaacac tacaggagct gcaaaagcaa taggcttagt aataccttca
     1921 ttaaaaggaa aattagatgg ggcagcacaa agagtaccag ttgtaactgg ttcaataact
     1981 gaattagttt gtacattagg aaaaaatgtt acagttgaag aaataaatgc agctatgaaa
     2041 gaagcttcaa acgaatcttt cggatatact gaagaaatgt tagtatcttc tgacataatc
     2101 ggaataagct acggttcatt atttgacgct actcaaacaa aagttatgga agtagatgga
     2161 aaacaattag ttaaagttgt ttcttggtat gataatgaaa tgtcttatac ttctcaatta
     2221 ataagaactt taggatactt tgcacaatta gcaaaatagt cagttttgag aaaatagaaa
     2281 agtagattga caaagtccga gtttgtagtt taatactacg gactcaggac tttttttaag
     2341 aaaaaatata taaaatacac ctaaataatg ttacatacta tatataaaaa tatgataata
     2401 tgatatattt aatagggtaa aagtatgtac tatattatac ttggcaataa aaaattactt
     2461 tattaaaagg agagatattt atgtcaatgc ttaacaaaaa aactatagaa gatattgatg
     2521 tgtgcggaaa aaaagtatta gtaagatgtg actttaatgt gccattacaa gatggtgtaa
     2581 ttactgatga aaatagattg aacggagctt taccaactat tcaatattta atttctaaag
     2641 gggcaaaagt tatattatgc tctcacttag gaaagccaaa aggagaagct aaaccagaat
     2701 tatctttagc accagtagca aagagattat ctgagatgtt aggaaaagaa gttgtatttg
     2761 cagcagacga taatgttgta ggagaaaatg caaagaaagc aactgaaaaa atggaaaacg
     2821 gagatgtagt attattagaa aatactagat atagaaaaga agaaactaaa aacgaagaga
     2881 atttctctaa agaactagca tcacttgctg aaatatttgt aaatgatgca tttggaactg
     2941 ctcatagagc acattgctca acagttggtg caggcgagtt tttacaagag agagtttgtg
     3001 gatacttaat tcaaaaagaa ttaaaattct taggagaagc tgttgcaaac cctgtaagac
     3061 catttacagc tatacttgga ggagctaaag tttctgataa attagctgtt ataaacgaat
     3121 tattagaaaa agttgataat ctaataatag gtggaggaat ggcttataca ttcttaaaag
     3181 ctcagggtta tgaagtagga acttctttac ttgaaataga taaagttgaa tatgctaaag
     3241 aaatgatgga aaaagctaag aataagggtg ttaacttatt attaccagta gacgttgtta
     3301 tggcagacca ctttgcacca gatgctactc caatagtaac agaagatgct aatgtaaaag
     3361 aagattacat gggactagat atgggaccta agactatagc aaactttgta aaaactataa
     3421 aagaatcaaa aactgtagta tggaatgggc caatgggagt atttgaattt gaaaactttg
     3481 caaatggtac attatcagta gctagagcta tggcagagtt gactgatgca actactgtaa
     3541 ttggcggtgg agatagtgca gcagcagtta atcaattagg atttggtgac aagatgactc
     3601 acgtatcaac aggtggagga gcatcactag aatttttaga aggtaaagaa ttaccaggta
     3661 ttgcagcatt agataataaa taaactaata tatagaggag attgtaaaat gagaaaacct
     3721 ataattgcag gaaactggaa aatgcataaa acaataaaag aagctttaga atttgtaaat
     3781 gaagttaaag ataaagtaaa ttctgataaa gtagaagctg ttatatgtgc accatttact
     3841 ttattaaagg atttaaaaga agctactaag ggtacaaata taaagatagg tgctcaaaat
     3901 atgcactttg aagaaaaagg agcatttaca ggagaagttt cacctcttat gttaaaagaa
     3961 atagatatgg actatgttgt aataggacat tcagaaagaa gacaatactt caatgaaact
     4021 gatgaaactg taaacaagaa agttttaaaa gcattagaag taggaataga cccaatatta
     4081 tgtgttggag aaactttaga acaaagagaa gctggaaaaa ctaaagatgt ttgtaaagtt
     4141 caagttgaaa aagctttaga aaatgttctt aaagatgatt tagcaaaagt agttgttgca
     4201 tatgagccaa tctgggctat tggaactggt aaaactgcaa ctgctgaaga tgctaatgac
     4261 gttatatctt atataagaga agttataaaa ggattatatg gagaattagc taatgaagtt
     4321 agaatacaat acggtggaag tgttaaacct tcaaatgtag ccgaaataat gggtcaaagt
     4381 gatatagatg gagctttagt aggtggagct agtttagcta gtaatgatta cctagacctt
     4441 gttaatttct aaggagtgaa atgatgaaaa aaccagttgc tttaattatt atggacgggt
     4501 ttggatacaa taaggatgtt aagggaaatg caattgctga gtccaaaact cctaatttag
     4561 atagaacaaa aaaagagtat ccaaacacat tgataaatgc tagtggtctt gatgttggtc
     4621 tacctgatgg tcaaatggga aattcagaag ttggacacac taacataggt gcaggtagaa
     4681 tagtatatca agatttaact agaataacaa aatctataaa agatggtgac ttttttacta
     4741 ataaagtttt atgtgaagca atggataatg caaaagaaaa ttctcttcat gtaatgggac
     4801 ttttgtctga tggaggagta cattcacata tagaccatct taaggctata atcaaaatgg
     4861 caaaagataa aggcgtacaa aaggtgtatg ttcacgcatt tactgatggt agagatactg
     4921 accctcaaag tgcattagaa tatgccaaag aagtacaagc tagtatggat gaaattggag
     4981 taggtgaatt tgctacagtt tctggtagat actacgctat ggatagagat aagagatggg
     5041 aaagagtaga acttgcatac aatgccatgg ttagaggtat tggtgaaaaa gcaaattcta
     5101 ttgaggaagc tattcaaaac tcttatgatg atggaaaaaa tgatgagttt ataatgccaa
     5161 cagttattat gaaagatgat aaaccagttg gaagtataaa ggaaaatgat tcaattatat
     5221 tctttaactt tagaccagat agagctagac aaataactag agctttagtt tgtgaagagt
     5281 ttgatgaatt taaaagagaa gatattaaaa acttctttgt atgcttaaca gagtacgata
     5341 taactataga gaatgtgcat atagcatttg gacctcaatc tttagccaac actctaggtg
     5401 agtatctagc taaaaatgga aaaactcaac ttagagctgc tgaaactgaa aagtatgcac
     5461 atgtaacttt cttcttcaat ggtggagtag aagagccaaa taaaggtgaa gaaagactat
     5521 tgataccttc tccaaaggtt gcaacttatg atttaaaacc agaaatgtca gcatatgaat
     5581 tgacagataa agctttagat aaattaggag aagataagtt tgactttata gtattaaact
     5641 ttgcaaatcc tgatatggta ggtcatacag gaagtataga agcggctata aaggctgttg
     5701 aaacggtaga cacttgtgta ggaaaattga tagataaaat agtagagtta ggtggaagtg
     5761 caataataac tgctgaccac ggaaatgctg aatatatgtt agacccagaa acaggaaaaa
     5821 ctgtaacggc tcactctatt aatccagtac catttattgt agttggtcaa gaatatgaaa
     5881 gtgcaaaatt attggatgga ggaagattat ctgatatagc acctactatt ttagatatga
     5941 tgaagttaga aaagccagaa gaaatgactg gtcattcact tatttcaaaa tagtcgattt
     6001 tgataagtag agaataatat ataaactaca atataaattt aaaaataatg cagtttaggt
     6061 ttattttgta aagtttagac tttatgacat aagatttaaa ttttgtaagt tctggatatt
     6121 gtaaggtgta gatgaagata tattttataa aatttacaag atagacaatt tataaaataa
     6181 aaaattacaa tatagataat aatgtaaata atgatataa
//
LOCUS       DAEORM030000110         6163 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.116, whole genome shotgun sequence.
ACCESSION   DAEORM030000110 DAEORM030000000
VERSION     DAEORM030000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6163)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6163)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 6163)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6163
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.116"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            121..771
                     /locus_tag="KRH23_003691"
     CDS             121..771
                     /locus_tag="KRH23_003691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HHS5226955.1"
                     /translation="MKAEKTSIYPIIKNNLNKISIVEYKKGQRFVASDKDLQEVFFII
                     EGVALVECTTRGGNKFLVDIVPENEFIGKISYIYEHNLKCDIFAKTNIKLFRFEKNVF
                     EEFYLKPDFIALFHRKCTRRIYELYKTRMVRELFSCTEVIAYCISNKQENNVCNIKAI
                     RNFSEIYSISRKSRYHSLLKLTEKEIVKKMGNTYEILNYDELHKLAFEVKEFLEDE"
     gene            complement(911..2287)
                     /locus_tag="KRH23_003692"
     CDS             complement(911..2287)
                     /locus_tag="KRH23_003692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042910 - xenobiotic transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006855 - xenobiotic transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HHS5226956.1"
                     /translation="MQELFSLKDENKRFYKILLSLCIPIIIQNLISTSVNVIDTIMIS
                     SLGETSVASVGVANQFFFLFNMSLSGITGGAGVFISQFYGKKDVSNIRKVTGLTCVLA
                     IVLSFVFVIPALLTPKPIIHIFSYDSEVVKLCIDYFSIAVFSYPLIAVSTVFSTGSRG
                     VRNPKLGMICSAFALVTNVILNYGFIFGNFGLPALGVKGAALATVIARICELILMITY
                     VYLYKKDYILKFGLKNLKAIDKIFIKSFSSKSFPIFVNDSVWAIGTVLYSVAYARAGT
                     SAIAASQIATSTGNFFIMTAVCIASGASIMLGNELGADHIKRAIEYAKKFSILVFSAG
                     LILGIILILNIPLLLKMFSVSDSLASDITKIFFIMGILMALKSFNTLVIIGILRSGGD
                     TKYALFLELGCMWLASIPLTFIAAFKGAPIFVLVLLTYSEEVVKFIFGVPRALSKKWA
                     INIVKEID"
     gene            complement(2303..4216)
                     /locus_tag="KRH23_003693"
     CDS             complement(2303..4216)
                     /locus_tag="KRH23_003693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HHS5226957.1"
                     /translation="MIVLSCNNLNKSFGIDSILENISFTVNEGDKIGIIGVNGTGKTT
                     LFKIISGIYGYDSGDIYTSKDCEIGYLEQNTNFYSDNTILEEVLEVFKNLIEMESYLR
                     ELEVRISEESTKPNSPIIEKIMDEYSHKLELFSDLNGYGYKSEAKGVLKGLGFSDNDM
                     DKPISILSGGEKTRVLLGKLLLKKPTLLLLDEPTNHLDSEAIEWLEVFLKQYKGTVML
                     ISHDRYFLDQSVNRIFEVHNKKLKVYNGNYSKFVELSKIEKELELKKFEDQQKEIKKQ
                     EESIERLKAYGREKHLKRARSKEKALDKVDVLDKPEAYRKKARIQFTPSVQSGNDVLQ
                     IRDVSMGYGERILFKDLDLDIYRGEKVALIGANGVGKSTLFKIITNELQPLSGNIKFG
                     TNVHVSYFHQEQKTLNLDNTIIDEIWENNTHLTQTTLRNMLGAFLFVDEEVFKKISTL
                     SGGERARVAILKLILSNANLLLLDEPTNHLDIDSKEVLEEALTNYDGTIFTISHDRYF
                     LNTVVDKILVLDENGITEYLGNYDYYIDKKRQIQEMSIIEEKEEKTRTQIKDEKRKER
                     EQREIEKKNRIKRQNIEKEIEKLEIEIEKLDILLCQEEVYSNPDKAKEVSQEKINLEN
                     NLASLYDEWEEFM"
     gene            4352..4984
                     /locus_tag="KRH23_003694"
     CDS             4352..4984
                     /locus_tag="KRH23_003694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA];
                     GO_process: GO:0051775 - response to redox state [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HHS5226958.1"
                     /translation="MLGNKNISMAVIRRLPKYHRYLGDLLDRDIQRISSKELSDIIGF
                     TASQIRQDLNNFGGFGQQGYGYNVEALHTEIGKILGLDRPYNAVLVGAGNLGQAIANY
                     AGFRKAGFEIKALFDANPRMIGLKIREFEVLDSDTLEDFIKNNNIDIAVLCIPKNGAQ
                     EVINRVVKAGIKGVWNFAPLDLEVPKGVIVENVNLTESLFTLSYLMKEGK"
     gene            5123..5662
                     /locus_tag="KRH23_003695"
     CDS             5123..5662
                     /locus_tag="KRH23_003695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FmdE family protein"
                     /protein_id="HHS5226959.1"
                     /translation="MVFVEELWKKAIEFHGHECPGLAIGFKAALAAREYLGCKQSGDE
                     EIVCISENDACGIDGIQVVLSCTMGKGNLLLRMTGKSVYHFFNRENGKSIRIYVKSKP
                     FQMDREGYKKYLLESDFEEIFEITDTKLRLPEKARIFKSLKCEVCGEFASEQYIRIEE
                     GKKVCLDCFNKYERFYEEY"
     gene            complement(5838..6008)
                     /locus_tag="KRH23_003696"
     CDS             complement(5838..6008)
                     /locus_tag="KRH23_003696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF362 domain-containing protein"
                     /protein_id="HHS5226960.1"
                     /translation="MAYKITDACISCGACEAECPVSCISAGDDAYVIDAGSCIDCGSC
                     AGACPVDAPQPE"
BASE COUNT         2275 a          860 c          864 g         2164 t
ORIGIN      
        1 gagtagaatg aatttgtcaa gtttaattta gttgtaattt tatcttttat taaaaataat
       61 ataaattaaa acatataaat aaaatatttt atacaatata ttgtaaagga ggtaactttg
      121 atgaaagcag aaaaaacaag tatatatcca attattaaaa ataatttaaa caaaatatca
      181 attgttgaat ataaaaaggg tcaaagattt gtagcatcag ataaagactt acaagaagtg
      241 ttctttataa tagagggagt tgcattagtg gagtgtacta ctagaggagg aaataaattt
      301 cttgttgaca ttgtacctga aaatgaattt ataggcaaaa tcagttacat atatgaacat
      361 aatttgaaat gtgatatatt tgcaaagacc aatataaaat tatttcgatt tgaaaaaaat
      421 gtatttgaag agttttatct caaaccagat tttattgcac tatttcacag aaaatgtaca
      481 agaagaatat atgaattata taaaaccaga atggtaagag aactattttc ttgcacagaa
      541 gttattgcct attgtatatc aaataaacaa gaaaataatg tctgcaatat aaaagctatt
      601 cgtaatttca gtgaaatcta ttcaattagt agaaaaagta gataccattc tctgctaaag
      661 ttaactgaaa aggagatagt aaaaaaaatg ggtaatacat atgaaatttt aaactatgat
      721 gaattacata aattggcatt tgaagtaaaa gagtttttgg aagatgagta aaaattgtta
      781 cttaatcaaa ataaagtata ataatttctg taaaaaatag aaatagtctc actgaaaatc
      841 aaaaatactt tagttatttt caatgagact gtttagaaat attgtatact tataatgtat
      901 agtataatta ttaatcaatt tcctttacta tattaatagc ccatttttta gataatgctc
      961 taggaacacc aaatataaac ttaaccactt cttcactata agtgagcaaa acgagtacaa
     1021 atataggtgc acctttaaat gcagctataa aagttagagg aatagaagct aaccacatac
     1081 atcctaattc taaaaataga gcatatttag tatctcctcc acttcttaaa ataccaatta
     1141 taaccaatgt attaaaagat ttaagagcca ttagtattcc cattataaag aatatcttag
     1201 ttatatcaga agctaagcta tcagaaacac taaacatttt taataataat ggtatattta
     1261 aaattaaaat aattccaagt attaaaccag ctgaaaatac aagtatagaa aactttttag
     1321 catattcaat ggctctttta atatggtcag ctccaagttc atttccaagc ataatagatg
     1381 caccagatgc aatacataca gctgtcatta tgaagaaatt acctgtactg gttgctatct
     1441 ggctagctgc tatagcagaa gtaccagctc ttgcatatgc aacagaatac aggacagttc
     1501 caattgccca tacagagtca tttacaaata taggaaagct ttttgatgaa aaagatttta
     1561 taaaaatttt atcaatagct tttagatttt ttagaccaaa ctttaatata tagtcttttt
     1621 tataaaggta aacataagta atcattaaaa ttaattcaca tattctagca ataacagtag
     1681 ctagagcagc accttttaca cccaatgcag gaagaccgaa gttaccaaat ataaatccat
     1741 aatttaaaat aacatttgtt acaagtgcaa atgcactaca aatcatacct aacttaggat
     1801 ttctaacacc tcttgaacca gtactaaata cagtacttac agcaattaat ggataactaa
     1861 atactgcaat actaaagtaa tctatacaaa gttttaccac ctcagaatca tacgaaaata
     1921 tgtgtataat tggctttggt gttagtaaag caggaataac aaatacaaaa cttaaaacaa
     1981 ttgccaatac acaagtaaga cctgtgactt ttcttatatt actcacatcc ttctttccat
     2041 aaaactgtga aataaaaact ccagcacctc ctgtgatacc agataaggac atattaaaaa
     2101 gaaagaaaaa ttggtttgca actccaactg aagctacaga tgtttcccct aaactgctta
     2161 tcataattgt atctattaca tttacagaag tagaaattaa gttctgtatg ataataggta
     2221 tacataaaga tagaagtatt ttataaaatc ttttattttc gtcttttaaa gaaaatagtt
     2281 cttgcaaata atcctctcct ttttacataa attcttccca ctcatcatat agagaggcaa
     2341 ggttattttc taaattaatt ttttcttggc taacttcttt agctttatct ggattagagt
     2401 atacttcttc ttgacataaa agtatatcta atttttcaat ttcaatctct aacttttcaa
     2461 tttctttttc tatattttgt ctttttattc tatttttctt ttctatttct ctttgttctc
     2521 tctcttttct tttttcatct tttatttgag ttctagtttt ttcttctttt tcttctataa
     2581 tactcatctc ttggatttgc ctttttttat ctatataata atcataattt cccagatatt
     2641 cagtaattcc attttcatct aaaactaaaa ttttatcaac aacagtattt agaaagtatc
     2701 tatcatgtga tattgtaaat atagtcccat cataattagt taatgcctct tcaaggactt
     2761 ccttagaatc aatatctagg tgattagtag gctcatctaa taacaataag tttgcatttg
     2821 atagtataag tttaagtatg gcaactctag ctctttctcc accactcaat gtagaaatct
     2881 tcttaaaaac ttcttcatct acaaataaaa atgcccctaa catatttctc aaagtagttt
     2941 gagtaagatg agtattattt tcccaaatct catcaattat tgtgttatct aaattaagag
     3001 ttttttgttc ctgatggaag taggaaacat gtacattagt tccaaattta atattgccac
     3061 taagaggttg tagttcatta gttattattt taaataatgt agatttgcca acaccatttg
     3121 cacctataag tgcaactttt tcccctctat atatatctaa atccaagtct ttaaaaagta
     3181 ttctttctcc ataacccata gatacatctc taatttgaag aacatcatta ccactctgga
     3241 cagaaggcgt aaattgtata cgagcttttt tcctataagc ttctggttta tctaaaacgt
     3301 ctaccttgtc taatgctttt tctttacttc ttgcacgctt taggtgtttt tctctaccat
     3361 aagcttttag tctttcaatt gattcttctt gcttttttat ttctttttgt tggtcttcaa
     3421 atttcttaag ctctagttct ttttctattt tagataactc aacaaattta gagtagttac
     3481 cattatatac tttaagtttt ttgttgtgaa cttcaaaaat tctatttacg gattggtcta
     3541 agaaatatct atcatgagat attaacatga cagtcccttt atattgtttt aaaaatactt
     3601 ctaaccattc tattgcttca gagtctaagt ggttagtagg ttcatcaagt aacaatagag
     3661 ttggtttctt aagaagtaat tttcctaaaa gaactctagt tttttcacca ccagaaagta
     3721 tgcttattgg cttatccata tcattgtcac taaatcctaa tccctttaga actcctttgg
     3781 cttcagattt atatccatat ccatttaaat ctgaaaataa ttctagttta tgtgaatatt
     3841 catccatgat tttttctata attggagagt ttggttttgt actttcttca gatattctaa
     3901 cctccaattc tcttaaatag gattccattt ctatcaaatt tttaaaaact tctagtactt
     3961 cttccaaaat agtattatcc gaataaaaat tggtattttg ttctaaatat ccgatttcac
     4021 aatctttaga agtgtaaata tctccactat catatccata aattcctgaa attattttaa
     4081 ataaagtagt ttttccagta ccattaacac cgattatacc aattttatcg ccttcattta
     4141 ctgtaaaact aatattttct aatatagaat ctataccaaa acttttattt aagttattac
     4201 atgacaaaac aatcataaat ttctacctcc ttgaactatc taaaattata atgttttgat
     4261 ataatataat caaggttata tgtattagtt ttgaaaaaga aatattttat tgtgaatcaa
     4321 acaaaaaaga ggacactttt aggaggtgaa gatgttggga aataaaaata tatcaatggc
     4381 agttataaga aggctcccaa aatatcatag atatcttgga gacttattag atagggatat
     4441 acaaagaata tcttctaaag aattgagtga tataataggg tttaccgctt ctcaaataag
     4501 acaagattta aacaactttg gtggatttgg acaacaagga tatggttata atgtagaagc
     4561 tcttcatact gagataggta aaattcttgg gttggatcga ccatacaacg cagttcttgt
     4621 aggagcaggt aacttaggac aagctatagc caattatgca ggatttagaa aagctggatt
     4681 cgagataaaa gctttatttg atgcaaatcc tagaatgata ggtttaaaga taagagagtt
     4741 tgaagtatta gattcagata ctttagaaga ctttataaaa aacaataata tagatattgc
     4801 tgtattatgt atacctaaaa atggagcaca agaagttatt aatagagttg taaaagctgg
     4861 aatcaaaggt gtatggaatt ttgcaccttt agatttagaa gttccgaaag gtgttatagt
     4921 tgaaaatgta aacttaacag aaagtttatt taccttatcg tatttaatga aagaaggaaa
     4981 gtagacaact taaacatatt aataatgagc agttgtgaag agtattgaga aagtcagaag
     5041 atttaatatt aaatcctctg gctttttgaa atattaggat aaaaatttaa ataatgtatg
     5101 gaaataaaca atattaagga gagtggtttt tgtggaggaa ttatggaaaa aggcaattga
     5161 atttcatggt catgaatgtc caggattagc tataggattt aaagcagcac ttgcagcaag
     5221 agaatattta ggatgtaaac agtcaggaga tgaggaaatt gtatgtattt ctgaaaatga
     5281 tgcttgtgga atagatggta tacaagtcgt gctaagttgc acaatgggta aaggaaattt
     5341 actacttagg atgactggga aatcagtata tcatttcttt aatagggaaa atggaaaatc
     5401 tataagaata tatgtaaagt caaagccatt tcaaatggat agagaaggat acaaaaagta
     5461 cttattagaa agtgattttg aagaaatatt tgagattaca gatactaagt taagacttcc
     5521 tgaaaaagca agaatattta aatctcttaa atgtgaagtg tgtggtgaat ttgcatctga
     5581 gcaatatata aggattgaag aaggaaagaa agtatgtctt gattgcttta ataaatatga
     5641 aagattttat gaggagtatt aaaattataa attagattaa agttaaaagt attagatatg
     5701 tgctaacagt attttaagat gaattaggta gcaacataat aaagtatata aataatatta
     5761 attgaatcat acataattaa aaagaggctg attagtattt ataaaataaa atcagtctct
     5821 ttatgaataa cgaattatta ttctggttga ggtgcatcta caggacaagc tcctgcacaa
     5881 gaaccacagt ctatacaaga accagcatct ataacatatg cgtcgtctcc agctgatata
     5941 cagctaacag ggcattcagc ctcacaagca ccacagctta tacaagcgtc agtaatttta
     6001 tatgccattt tgaaatcctc ccttttatat gtattgtaat tcaataacat tataacaaat
     6061 attattgaat ataacaatta aattaattct acaacaaaaa ctttattatg atattcttgt
     6121 tttaaagttt tacaataaag tttaatctgc ttatattttt att
//
LOCUS       DAEORM030000111         6043 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.117, whole genome shotgun sequence.
ACCESSION   DAEORM030000111 DAEORM030000000
VERSION     DAEORM030000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6043)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6043)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 6043)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6043
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.117"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            complement(1163..2569)
                     /locus_tag="KRH23_003697"
     CDS             complement(1163..2569)
                     /locus_tag="KRH23_003697"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HHS5226961.1"
                     /translation="MDSVKYILRRFIGSSILISLLFIVLNIAGFLLFSYMLFVSKYSD
                     NLDTSDSREIKSNLIMIEDNLVLKDGKFILDDSSKEILHKNKVWAMLIDNNGDRIWGF
                     DLPKEIPSHYTLTDVAKFSRFFLKDYPVYVWEHPNGILVTGYPKDKYTKFNLTYTVKE
                     IEQFPMLIIGMFLVNAIVTFLIALFIGLKMVKSIKPIITGIKLMSKGEPVLLQEKGIL
                     SDISKSINTVSKELQMKDEKLRKKEEARSNWIAGISHDIRTPLSMIIGYAGELEESSS
                     LSNREQEQVSIICNQGIKIRELVNDLNLVSKLEYNMQALNCDKIRVSAFLRELISEFI
                     NNNLDNDFYVELDILNEDIIIDADKKLLKRAISNLIQNSITHNQQGCNIRVTSKSDLD
                     FCYIIVEDDGKGMSQERINSLLKSQNGLSEAYAKGQNHGLGILIVSGIINAHRGKLDI
                     TSIDSQGLKTILKLPLIK"
     gene            complement(2614..3321)
                     /locus_tag="KRH23_003698"
     CDS             complement(2614..3321)
                     /locus_tag="KRH23_003698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HHS5226962.1"
                     /translation="MESIKDKKILVVDDHKELLKMIDEILRKEGFSRVFLASSYEEAV
                     RVFRNVKPDCAILDVVLPDGDGFSIMRKIRETSKIPVIFLSARGEDEDRLIGLGLGAD
                     DYIVKPFLPKELTLRLVGILNRVYVPIEEEELPVFKLGDSVVVNLNSACVEKEGQEIS
                     LTAKEHSLLLKLYENKGRIVTNDSLCQAIWGDDMYGYENTLMVHVRRVREKIEKTPST
                     PKHLITVRGLGYKLMIN"
     gene            3492..4406
                     /locus_tag="KRH23_003699"
     CDS             3492..4406
                     /locus_tag="KRH23_003699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHS5226963.1"
                     /translation="MEMIIRTQRLSKEYNKIFRVKDIDLRVSQGAVYGFLGPNGAGKS
                     TTLKMLLGLAKPTQGNINILGKELNEKNRISILKDIGSLIESPSYYGHLTGLENMTIM
                     QRLLDLPKKNVNEALKIVRLENQKNKKVSQYSLGMKQRLGIAMAIMKFPKLLILDEPT
                     NGLDPAGIEEIRELIKSLPEKYGMTVLISSHLLSEIDQIATSIGIINHGELVFQDSIK
                     ELHNRGQSQIAIKTKNVVSAQKLLNTKGYMSLIQDGYLTIENLKDSDVAKINGMLVHS
                     NIDVFRIEEHKKSLEDIFLELTGKAVTL"
     gene            4406..5167
                     /locus_tag="KRH23_003700"
     CDS             4406..5167
                     /locus_tag="KRH23_003700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHS5226964.1"
                     /translation="MKYLGLEFYKLKRKKIILMTFLFVAVEIMWCIVNSNRAITRNPD
                     MLGGFEYSYMLMSFASLNGLFFPILISIITSRISDIEHKGDTWKLLKSSVTSLNSIYL
                     SKFLCSAILVSIPVLMQVLSIVLFGHFRGVIESISVSLLLKYTLGTILVSIAIIALHL
                     WIATVIPNQMIAITFGMIGSFIGLTSGLFYQGIRRLFIWSYYLELSPLSYAYDNVLGS
                     SVYRIDMNFSITILVFLIGMLIYYIGRNHLLKKEV"
     gene            5179..5916
                     /locus_tag="KRH23_003701"
     CDS             5179..5916
                     /locus_tag="KRH23_003701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHS5226965.1"
                     /translation="MLRKSVLGEILKLKNSFIWYVLLALPLISVLIGSGNFYLNQGIL
                     KKEWYSLWTQVSLFYGEFFFPILIAIFCAYICRLEHMNHNWNNVMTLPVNLKNIFLSK
                     LTVVSILTAITQVFFVIFYIVAGNMFGFSGSVPKELTGWIAKGWIISISIASIQLYMS
                     IKIRSFATPIGISLCLSLFGMGLIVAKPAVGIFFPYSMLGSAMGVIKQSALNVNDTIV
                     TICVAFITTIVFSEIANRNFRKNDVIS"
BASE COUNT         2078 a          957 c          715 g         2293 t
ORIGIN      
        1 cacttactaa actttttatt tactataact tattactgaa cttctcactt actaaatttc
       61 ttacttacta taaattataa ctaaacttct cacttactaa atttcttact tactataaat
      121 tattactaaa tttcctactt tctaaatttc ctactttcta aatttcttac ttgctataaa
      181 ttattactaa acttcctact ccctaaattt cttacttgct acaaattatt actaaacttc
      241 ctacttccta aatttcttac ttactactac ttataactaa acttcccact tcctaaattt
      301 cttacttact accacttata actaaacttc ccacttccta aatttcttac ttactaccac
      361 ttataactaa acttcctact ttctaaattt cttgcttact accacttata actaaacttt
      421 ttacttctta aatttcttac ttcttaagaa taatgttaat tttaatttta agattatagt
      481 ttttgccttg tttaattgaa acattctata taattatatc cttctatttt agagtttttt
      541 tatttatata ttacaaagtt taaatttttt cattaattat attataaatt ttccatatat
      601 ttcaacataa atacacatat atatatgtta tctctaaaaa tactacacaa aaactctact
      661 ttagtagaac tcaatggcgc aaaatacttc aatttaaaac atttatcgta ctttaaataa
      721 ataactataa taaaatatac ttacaatagt tacatagaag ctattataac tacacagaac
      781 aacgtataat taaaactttt ttaggatgtc attatatttt ttcttaaaat taaaaaacac
      841 tataccataa ttctatttta gtagaatttt tttgtcaata ataaaattaa atattaacta
      901 aaaaataaaa aaaatggaat tatctaaaga atttaataac cttacaataa ttccaaaata
      961 ttatttctat gaaaattttg ataccatgag taactcagcc ataagcgcat aaagcacaag
     1021 ttactcttta ctttaataaa acttgacaag aaaagaattt attcttattc tactctaata
     1081 gagttaattt gtcaataaag aataaaatta ttttcaaaat attttcattc ttcattctta
     1141 tctgttatta ttttataaaa tatcacttaa ttagaggtaa ttttagtatt gtttttagtc
     1201 cctgactatc aatgctcgta atatctaatt tacctctatg tgcattaata atgccagata
     1261 ctatcaaaat acctagacca tgattttgac ctttggcata tgcctcactt agtccatttt
     1321 ggctctttaa taaactatta attctttctt gactcatacc ttttccatca tcttcaacaa
     1381 ttatatagca aaaatctaaa tcagacttag aggtaaccct tatattacat ccttgttggt
     1441 tatgagttat actattttgt attaaattac taatagccct ttttaataat tttttatctg
     1501 catctataat aatatcttca tttagtatat caagttcaac gtaaaagtca ttatccaaat
     1561 tattatttat aaactcagaa ataagctctc tcaaaaacgc agaaactcta atcttatcac
     1621 aattcaatgc ttgcatatta tattcaagtt tagacactaa atttaggtca tttactaatt
     1681 ctctgatttt aatcccttga ttgcatataa tagacacttg ctcttgttct ctatttgaaa
     1741 ggctactgct ttcttcaagt tctccagcat atccaattat cattgaaagt ggagttctta
     1801 tatcatgaga tattcctgca atccagttag acctagcttc ctctttcttc ctaagttttt
     1861 catctttcat ttgcaattct ttagatacag tattaataga ttttgaaata tcacttagta
     1921 ttcctttttc ttgtaaaagt actggttctc cttttgacat aagctttatg ccagtaataa
     1981 ttggttttat agatttcacc atttttaaac ctatgaatag agctattaaa aaagtaacta
     2041 ttgcattaac caaaaacata cctattatta acataggaaa ttgttctatt tccttaaccg
     2101 tataagtaag gttaaactta gtgtacttgt cttttggata acctgttact aatattccat
     2161 ttggatgttc ccatacatac acaggatagt cctttaaaaa gaaccttgaa aactttgcta
     2221 catctgtcaa agtataatga cttggaattt cttttggtaa atcaaatccc catattctat
     2281 ctccattgtt atcaattaac attgcccaaa ctttattttt atgtagtatt tccttactag
     2341 aatcatctaa aataaacttt ccatctttta aaaccaaatt atcttcaatc ataatcaagt
     2401 ttgattttat ttctctgcta tcacttgtat ctaaattatc agagtattta gatacaaata
     2461 acatatatga aaacagaaga aaacctgcta tatttaatac aataaaaagt aatgaaatca
     2521 agatacttga acctataaat cgcctcaata tgtactttac actatccaaa attaaatcac
     2581 tcctcttgat ttcttttatt ctaatatcta aaattaatta atcatcaact tatatccaag
     2641 acctcttact gtaataagat gtttaggtgt agatggagtt ttttctatct tctctctaac
     2701 ccttctaaca tgaaccataa gggtattttc atatccatac atatcatctc cccaaatggc
     2761 ttgacatagt gaatcattag taacaattct ccctttattt tcatacaact ttaaaagcaa
     2821 cgaatgctct ttagctgtta aagaaatctc ttgcccttct ttctcaacac atgcactatt
     2881 taaattcaca acaacagaat ctcccagttt aaatactggc aactcctctt cttctatagg
     2941 cacatataca cgatttaata tacccacaag ccttaaagta agttcctttg gtaaaaatgg
     3001 ctttactata taatcgtcag cccctaagcc caaaccaatc aatctatctt catcttcacc
     3061 tcttgcagag agaaaaatca ctggtatttt agatgtctct ctaatttttc tcataataga
     3121 aaaaccatct ccatctggca atacaacatc taaaattgca caatctggct ttacatttct
     3181 aaatacccta acagcttcct cataacttga tgctaaaaat actctactaa atccctcttt
     3241 tctcaggatt tcatctatca tttttaataa ttccttgtgg tcatcaacca caagtatttt
     3301 tttatctttt attgactcca taatcatcac cctcctttag tataccatat acccattttc
     3361 acaactttgc ctaaatagac ttttaaggtt attgtaaggt aaatttcagc taactgaaat
     3421 gtaaccaagt tattatactg atataagtta aaagaatcaa taagcacaga ttaaaaaagg
     3481 ggatgaaaca tatggaaatg ataattagaa cacaaagact ttcaaaggaa tacaataaaa
     3541 tatttagagt aaaggatata gacctaagag tttcacaagg agctgtatat ggttttttgg
     3601 gtcctaatgg agctggaaaa tctaccactc ttaaaatgct tcttggactt gctaaaccca
     3661 cacaaggaaa tattaatatt ttaggtaaag agttaaatga aaaaaataga atatcaattt
     3721 taaaagatat aggttctttg atagaatctc catcatacta tggtcatctt acagggcttg
     3781 aaaacatgac cataatgcaa agactcttag atttacctaa aaaaaatgta aatgaagcat
     3841 taaaaattgt aaggttagaa aatcaaaaaa ataaaaaagt tagtcaatat tctttaggta
     3901 tgaagcaacg tcttggcatt gctatggcaa taatgaagtt tcccaaatta ttaatacttg
     3961 atgaacctac aaatggactc gacccagcag ggattgagga aattagagaa ttaataaaat
     4021 ctctaccaga aaaatacggg atgactgttc taatctctag ccatctttta agtgaaattg
     4081 accaaattgc cacatcaata ggaataataa atcatggcga actggttttt caagatagca
     4141 taaaagaact tcataataga ggtcaaagtc agattgctat caaaactaag aatgttgtat
     4201 ctgcacaaaa actattaaat actaaaggat atatgtcact tatacaagat gggtacttga
     4261 ctattgaaaa tttaaaagac tcagatgtag ctaaaataaa cggtatgctt gtccattcaa
     4321 atatagatgt atttagaata gaagaacata aaaaaagctt ggaagatata ttcttagaac
     4381 ttactggtaa ggcggtgact ttataatgaa ataccttggt ctagaatttt ataaacttaa
     4441 aagaaagaag attattctga tgaccttttt atttgtagct gttgaaataa tgtggtgtat
     4501 cgtaaattca aatagggcta ttacacgtaa tccagatatg ttaggtggat ttgaatattc
     4561 ctatatgctt atgagttttg caagtttaaa tggtctattc tttcctatct taatatcaat
     4621 aattacatca cgtataagcg atatagaaca taaaggagat acatggaagc ttttaaaatc
     4681 ttctgtgaca tctttaaata gtatttattt atctaaattt ttatgttctg ctattttggt
     4741 atctatacct gtattgatgc aagtgttatc tattgtgttg tttggacatt ttagaggggt
     4801 tattgagtca atttctgtat ctttactttt aaaatataca ttaggaacaa ttcttgtaag
     4861 tattgctatc attgcgctac acctatggat tgcaactgta attccaaatc aaatgattgc
     4921 aattacattt ggcatgattg gtagttttat aggtttgaca tcaggtttgt tttatcaagg
     4981 tattcgtaga ttgtttatat ggtcttatta cctagagtta tcacctttaa gttatgccta
     5041 tgataatgtt ttaggttcat ctgtctatag aattgatatg aatttttcta ttacgatttt
     5101 agttttctta attggaatgc taatttatta tattggaaga aatcatttat taaaaaaaga
     5161 agtataggag ggatttaaat gttaaggaag tcagttttgg gagaaattct aaagttaaaa
     5221 aattctttta tatggtatgt attattagct ttgccactta taagtgtgtt gattggttct
     5281 ggtaattttt atctaaatca aggcatactc aaaaaagaat ggtacagctt atggactcaa
     5341 gttagtcttt tttatgggga atttttcttt cctatcttaa tcgcaatctt ttgtgcatat
     5401 atttgtaggc ttgaacatat gaatcataat tggaataatg taatgacact gccagttaat
     5461 ttaaaaaata tctttttatc taaacttaca gtagtttcaa tacttacagc tattacacaa
     5521 gttttctttg ttatctttta tatagttgca ggaaatatgt ttggtttttc tggtagtgta
     5581 cctaaagaat tgactggttg gattgctaaa ggttggatta tttctatttc aatagcttct
     5641 atacaattat acatgtctat aaagattaga agttttgcaa ctcctattgg tattagtctt
     5701 tgcctttctc tatttggtat gggattaata gtagcaaaac ctgctgttgg tatatttttc
     5761 ccttattcta tgttaggtag tgctatgggg gttataaagc aatctgcttt aaatgttaat
     5821 gacactatag ttacaatatg tgttgcattt attactacta tagtattttc tgaaattgcc
     5881 aatagaaatt ttagaaagaa tgatgttatt tcttaatggt aaatgctaga tatttttggg
     5941 tttgaaattt atattctttt tagttgaaat ctatatccat tttatttaaa aatatatatc
     6001 ttttatttga attttatatg ttttatctac tcgctatata ata
//
LOCUS       DAEORM030000112         5836 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.118, whole genome shotgun sequence.
ACCESSION   DAEORM030000112 DAEORM030000000
VERSION     DAEORM030000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5836)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5836)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 5836)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5836
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.118"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            complement(239..2071)
                     /locus_tag="KRH23_003702"
     CDS             complement(239..2071)
                     /locus_tag="KRH23_003702"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHS5226966.1"
                     /translation="MSRMGRGPMGKSMGAGQKANDFKGTMRKLIAYLSKFKISIILVI
                     VFAIGSASFSIVGPKILGKATTKIFEGLVSKVSGGNVGIDFNAIGKILTFLLFLYLIS
                     ALFSFIQGFIMSGISQKVSYNLRKEISAKLDRLPMKYFDTKTHGEILSRITNDIDTLN
                     QSLNQSMTQLITSVTTMIGVLIMMLSISGIMTLVAVLILPISMFVISRIIKKSQKYFR
                     YQQEYLGNVNGQVEETYSGQTIVKAFNREDEVIEEFDKLNDSLYNSAWKSQFLSGIMQ
                     PLMMFIGNLGYVMVSILGGWLAIKKTIEVGDIQSFIQYVRNFTQPMTQIAQVANLLQS
                     TAAASERVFEFLEEEEEVQIVENAVSIDGLEGKIDFENVNFGYNPNKTIINDFSVNVK
                     PGQKVAIVGPTGAGKTTIVKLLMRFYDVNSGSILIDGHNIKDFNRSELREMFGMVLQD
                     TWLFSGSIMENIRYGKLNATDEEVIEAAKSAHVHRFIKTLPDGYKMKLNEEASNVSQG
                     QKQLLTIARAILADPKILILDEATSSVDTRTEVLIQKAMDNLMEGRTSFVIAHRLSTI
                     RDADMILVMNEGDIVEQGNHEELLKKGGFYANLYNSQFEEDEAM"
     gene            complement(2064..4310)
                     /locus_tag="KRH23_003703"
     CDS             complement(2064..4310)
                     /locus_tag="KRH23_003703"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHS5226967.1"
                     /translation="MFKLIKYLKKSALSIVIIVCLLVIQAVCDLSLPEYTSNIVNVGI
                     QQGGVENSVPSVIRESELNKITLFMDKSSKDKVLDNYTLLNKKDYVKYKDKYPGLKDE
                     SLYELNTKDKDTIDDLNVIFGKAILIVSGLEGDSKEVKAMKAQLMSKLPPQATQSGDV
                     DIFKLLSAMPKEQLDTLTKEMSKGFESMPESMITQSSVSYVRSEYEKIGIDTEKTQNN
                     YILFTGAKMLGIAMISMVATITVGFLAARVAASVGRNLRSGVFRKVMSFSNTEMNEFS
                     TASLITRSTNDIQQIQMLMVMLLRIVFYAPIMAIGGVIKVLNTNTSMAWIIAVAVVAI
                     LSLIVVLFSVVMPKFKLVQKLVDKLNLVSREIITGIPVIRAFSTEKHEEERFDKANKN
                     LTKTNLFVNRVMTCMMPAMMLIMNLITVLIVWRGAYSVDSGAMQVGDMMAFIQYTMQI
                     IMSFLMISMVSIMLPRASVSATRIDEVLVSDISIKDPEKSEAQEFKEDKKGLVEFKNV
                     SFMYPDAEEPILTNISFTAKPGETTAFIGSTGSGKSTLINLIPRFFDVTEGEILLGGV
                     NIKNVSQHDLREKIGYVPQKGVLFSGTIESNLKYGRKDATDEEMRTAAEIAQATEFID
                     SKPEAFKTEISQGGTNVSGGQKQRLSIARAIAKNPEVYIFDDSFSALDLKTDAALRKA
                     LKSKTAESTVLIVAQRISTILNAEQIIVLNEGEIVGIGTHKELLKNCEVYEQIALSQL
                     SKEELANE"
     gene            complement(4378..4839)
                     /locus_tag="KRH23_003704"
     CDS             complement(4378..4839)
                     /locus_tag="KRH23_003704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HHS5226968.1"
                     /translation="MNSNSEEKLNDVFLQLMRIYFIRTHFYFDKLGLYHGQPQILFSL
                     KMKDGQSQKELADKRKVKASTTTVMIKRMEKAGLVERKQDEKDQRVSRIFLTDKGLEI
                     CNKVEEFNKELEREFFLGFSEEEKIVLRRLLMQVRDNLKAGCHKHEDEKYF"
     gene            complement(5144..5710)
                     /locus_tag="KRH23_003705"
     CDS             complement(5144..5710)
                     /locus_tag="KRH23_003705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004089 - carbonate dehydratase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-class carbonic anhydrase"
                     /protein_id="HHS5226969.1"
                     /translation="MRKLEEILEYNKSFVENKEYEQYVTSKHPNKKIVVLSCMDTRLT
                     ELLPKAMNLKNGDVKLIKNAGATIMHPFGSIMRSVLVAIYEFDVDEVMVVGHHGCGMC
                     NVDTDKLLGKILDRGISNDVILTLRSAGIDTKQWLHGFDSAEESVKDSIDLIKGHPLI
                     PDGIIVHGLIISPETGKLDVVVNGYEDK"
BASE COUNT         1864 a         1082 c          629 g         2261 t
ORIGIN      
        1 gataatcacc tccaacattt tccttactac atattataat aaaataaaca ctttgtaaag
       61 acataaaatt atgtggctat ctcaaaatat agagaatcct ctttttcatt gttaaaatga
      121 taaaaataca ttttatttca tacacaaaag agtgccttat gaattaaaaa gttcatttta
      181 aggcaccctc atttatttta tcttattaat tacatgtcta tgctaagata gttttttgtt
      241 acattgcttc atcttcttca aattgagaat tgtaaagatt ggcatagaat ccgcctttct
      301 ttagaagttc ctcatgattt ccttgttcaa ctatatctcc ttcattcatt acaagaatca
      361 tatcagcatc acgtatagtt gataatctgt gggctataac aaaacttgtt ctaccttcca
      421 taagattatc catagctttt tgaatcaata cttctgttct agtatcgaca gaacttgtag
      481 cttcatctaa tattaaaatt ttaggatcag ctaaaatagc acgagctata gtcaataatt
      541 gtttttgacc ttgagaaaca ttacttgctt cttcatttaa tttcatctta tatccatctg
      601 gtaatgtctt aataaatcta tgaacatgtg cagatttagc agcctctata acttcttcat
      661 ctgtagcatt caacttacca tatcttatat tttccataat tgaaccacta aataaccatg
      721 tatcttgaag aaccatacca aacatttctc taagctcact acgattaaaa tctttaatat
      781 tatgaccatc aatcagtatt gaaccgctat taacatcata aaatctcatt aacagtttaa
      841 ctattgtagt tttacctgct cctgtaggtc caacaatagc aactttttga ccaggtttaa
      901 catttactga gaaatcattt attatagtct tgtttgggtt atatccaaag ttgacatttt
      961 caaaatcaat tttaccttct aaaccatcta ttgaaactgc attttcaaca atttggactt
     1021 cttcttcctc ttctaaaaac tcaaatactc tttcagaagc tgctgctgtt gattgtaata
     1081 aattggcaac ctgtgcaatc tgagtcattg gctgtgtaaa gtttcttaca tattgtataa
     1141 atgactgtat gtcaccaacc tcaattgttt tcttaattgc aagccaacct cctaagattg
     1201 ataccattac atatcccaag tttccaataa acatcataag tggttgcatt atacctgata
     1261 aaaattgaga tttccacgct gaattataca ggctatcatt taatttatca aactcttcaa
     1321 ttacttcatc ctcacgatta aatgctttta ctattgtttg accactgtaa gtttcttcaa
     1381 cttgaccatt tacatttcct aaatattctt gttgatatct aaagtatttt tgtgatttct
     1441 ttattattct tgaaattaca aacattgata ttggtaatat taaaactgcc actaatgtca
     1501 taattccact tatagataac atcattatca aaacacctat catagttgtt actgatgtta
     1561 taagctgtgt catactttga tttaaacttt gatttaaagt atctatatca ttcgtaattc
     1621 tcgataatat ttcaccatgc gtcttagtat caaaatactt cattggcaat ctatccaatt
     1681 ttgctgaaat ctcttttctt aaattatagg atactttttg agaaattcca ctcattataa
     1741 atccttgtat aaaagagaac agtgcactta tcaaataaag gaaaagtaaa aaggttaaga
     1801 tttttccaat tgcattaaaa tctataccta cgtttcctcc agaaacttta ctcactagcc
     1861 cttcaaatat ctttgtagtt gcctttccta aaatttttgg acctactata gaaaacgacg
     1921 cactaccaat agcaaataca attactagaa ttattgatat tttaaattta gataaatatg
     1981 caattagttt tcgcatagtc cctttaaagt catttgcttt ttgtcctgct cccatagatt
     2041 ttcccatagg acctcttccc attctactca ttagctagct cctcctttga aagttgtgat
     2101 aaagctattt gctcataaac ttcgcaattt tttagaagct ctttatgtgt tcctattcca
     2161 actatttcgc cctcatttaa aacaattatc tgttctgcat ttaagatagt actaattctt
     2221 tgtgcaacta ttagaactgt actttcagca gtttttgatt ttaaagcctt acgaagagct
     2281 gcatcagttt ttaagtcaag tgctgaaaaa ctatcatcaa atatataaac ttctggattt
     2341 tttgctattg ctcttgcaat agaaagtctt tgtttttgac ctccagatac atttgttcca
     2401 ccttgagaaa tttcagtttt aaaagcttcc ggtttagaat ctataaattc tgtagcttga
     2461 gctatttcag ctgctgttct catttcttca tctgttgcgt cttttctacc atattttaag
     2521 ttggattcta tagtaccaga aaacaatact cccttttgag gtacatatcc aattttttcc
     2581 cttaaatcat gttgagaaac attttttata ttaactccac caagtaatat ttctccttca
     2641 gtaacatcaa agaaacgagg aattaaattt ataagagttg acttaccact accagtactt
     2701 cctataaagg cagttgtttc tcctggcttt gctgtaaaag atatatttgt taatataggt
     2761 tcttctgcat ctggatacat gaacgaaaca tttttaaatt caacaagacc ctttttatct
     2821 tccttaaact cttgtgcctc tgatttttct gggtctttta tgcttatatc tgacactaat
     2881 acttcatcta tacgtgtagc tgaaacggat gctcttggaa gcataataga taccattgat
     2941 atcattaaga atgacattat tatttgcatt gtatattgta taaatgccat catatctcca
     3001 acttgcattg ctccagaatc aacactgtat gcacctctcc aaactataag aactgtgata
     3061 aggttcatta taagcatcat agcaggcatc atacatgtca taactctatt tacaaaaaga
     3121 tttgttttag ttaaattttt atttgcttta tcaaatcttt cttcttcatg tttttcagta
     3181 ctaaaagctc tgataactgg aataccagta attatttcac ggcttactaa gtttaactta
     3241 tcaacaagct tttgaaccag tttaaactta ggcataacca ctgagaataa cactacaatt
     3301 aatgataaga tagcaactac tgctactgct ataatccagg ccattgaagt atttgtgttt
     3361 aaaaccttta tcactccacc tatagccatt ataggtgcat agaatactat tctaagcaac
     3421 ataaccatca acatttgtat ctgttgaata tcatttgtac tacgagtaat taatgaagct
     3481 gtagaaaatt cattcatttc agtatttgaa aatgacataa cttttctaaa tactccactt
     3541 cttaaatttc tacctacact tgcggctact cttgctgcta aaaatcctac tgttattgta
     3601 gctaccatac taatcattgc tataccaagc attttagcac cagtaaataa tatataatta
     3661 ttttgagttt tttctgtatc aatacctatt ttctcatatt ctgaccttac atatgaaaca
     3721 gagctttgtg ttatcatact ctctggcata ctttcaaagc ctttgctcat ctctttagtc
     3781 aatgtatcta actgttcctt tggcattgct gataacaatt taaatatatc aacatctcca
     3841 ctttgagtag cttgtggtgg aagtttactc attaactgag ctttcatagc ttttacctct
     3901 ttactatcgc cctcaagccc tgatactatt aaaatagctt taccaaaaat aacatttaaa
     3961 tcatctatag tgtctttgtc tttagtattt aactcataaa gagattcatc ttttagacct
     4021 gggtacttat ctttatactt aacataatcc tttttattca gcaaagtata attatctagt
     4081 actttatcct tactactttt atccataaat aaagtaattt tatttaattc actctctcta
     4141 atcacagatg gaacagagtt ttctactcca ccttgttgta tacctacatt tactatattg
     4201 gatgtgtatt ctggtaaaga aaggtcacat accgcttgaa ttaccaatag acagactatt
     4261 attactattg ataatgccga tttctttaaa tatttaatta atttaaacat acatttcttc
     4321 ccttctgtaa tattaattag tctaataaca ttaaattgaa aaacattatt ttaaacttta
     4381 aaaatatttt tcatcttcat gcttatgaca tcctgctttt aaattatctc gtacttgcat
     4441 tagaagtctt ctaagtacta ttttttcttc ttcactaaat cctaaaaaaa actctctttc
     4501 caattccttg ttaaattctt caactttatt acatatttct aaacctttgt ctgtcaaaaa
     4561 aatcctagat actctttggt ccttttcatc ttgttttctt tccacaagtc cagctttttc
     4621 catcctcttt atcataactg tagttgtgga tgcttttact ttccttttat ctgctaattc
     4681 tttttgactt tgcccatctt tcatctttaa agaaaaaagt atttggggtt gaccatgata
     4741 taagcctaat ttatcaaaat aaaaatgagt tcttataaaa tatattcgca ttaattgcaa
     4801 gaaaacatca tttaattttt cttcagaatt gctattcata cttgccctcc ttatttttta
     4861 tattacttag tcagctaagt attattttac tatactgcat gcattttttc aatatattta
     4921 taaaaaattc atataaattt catttattaa atatttttat atcatatagt tataatttta
     4981 ataaataata gtaagatttt taattagtca gctacttata ttttttattg taaagcttaa
     5041 aataaacctt ttcatatatt ttcaaataaa aaagttgtcc caaaataaat tttgaaacaa
     5101 catcttattc aacagtatct tgattatata acattatgat actctactta tcttcatatc
     5161 catttacaac aacatctaac ttcccagttt caggtgatat aattagacca tgtacaataa
     5221 taccatctgg aattaaagga tgccctttta ttaaatcaat actatctttt acagattctt
     5281 ctgcagaatc aaatccatgt aaccattgtt ttgtatcaat tccagcacta cgaagtgtaa
     5341 gtattacatc attagatatt cctctatcta aaattttacc aagtaactta tccgtatcaa
     5401 cattacacat accacatcca tgatgcccta caaccataac ctcatctaca tcaaattcgt
     5461 aaattgcaac taaaacactt ctcataatac ttccaaaagg atgcattata gtagctcctg
     5521 cattttttat tagtttcaca tctccatttt tcaaattcat agccttaggc aaaagctcag
     5581 ttaatcttgt atccatacaa gataagacta ctattttttt atttggatgt tttgatgtca
     5641 catattgttc atattctttg ttctctacaa atgatttatt atattctaat atctcttcaa
     5701 gttttctcat atgtaatatc accctcttta aaaatttttt tattattata tcactattaa
     5761 agtacaatat atacacatat aatttaattt atatttatta aattatttta taagattatt
     5821 actctactat aaatct
//
LOCUS       DAEORM030000113         5817 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.119, whole genome shotgun sequence.
ACCESSION   DAEORM030000113 DAEORM030000000
VERSION     DAEORM030000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5817)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5817)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 5817)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5817
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.119"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            complement(72..506)
                     /locus_tag="KRH23_003706"
     CDS             complement(72..506)
                     /locus_tag="KRH23_003706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226970.1"
                     /translation="MKVGNINGQAPITNGLDSCQSEVQGLEQKKKALQDEIEKVRSDK
                     SIDGETAKLKIEALKKEIEEIENKIQELKGNKAQKTNKEENNVSEVNNNLLERKKESS
                     NNENVKQLYDVFERSSEDEQWDNTYRVLQDDKNLKVKFNRPI"
     gene            complement(596..1954)
                     /locus_tag="KRH23_003707"
     CDS             complement(596..1954)
                     /locus_tag="KRH23_003707"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HHS5226971.1"
                     /translation="MINLFSSDLFLKYNFFFSFIVYRILMVIVQYYFLISFTNVNSKF
                     WCFILYSIISIFLIIINTYFNLCNLFSSQILLFLMTFLFVKYIIKQSTVLSIVSTLLV
                     YLIEQLAYGFTAPLNYLIFTSDINTDIYKFDINMGLSSLITIIIAGFIYWYSSKKFNI
                     KVMNFDKYLAILMIPLLLIILFMQSFEYSSNINIDTSLGIVKLLLNTSITEEIQAFLF
                     SIIGTICVFFSLFTFKKLIQALEDEKERAIMNQQIHAQRNYIEEAKSRLSQTISFRHD
                     FNNHLAIVNGLLKKDQILKAQDYLNKLEKVTSDLSFSCNTQNIVIDALFNNKLSIAKQ
                     LGIEVDCEVIIPQSTNMNDFDLCIVFANAIDNAIKACRVVDKQNRYLKLSTKLEGGFF
                     MIEIKNSYNPINNYTSGSGIGLLNIKEIAKKYQGAISIDKTSDYFQINVLLVISLHCA
                     SI"
     gene            complement(1956..2687)
                     /locus_tag="KRH23_003708"
     CDS             complement(1956..2687)
                     /locus_tag="KRH23_003708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytR/AlgR family response regulator
                     transcription factor"
                     /protein_id="HHS5226972.1"
                     /translation="MIRKKVYILISIAICDDESYMLNHLKENIELYMKQKNLLYNIEL
                     FNKVEDLLCNHEKFNIVFLDIQMEEINGMQAARKLRSYGNECFIIFVTVLNEFVFDAF
                     EVDAINYLIKPLSNEKLYKTLDKIVTKLEDNESNYITIQKGYSYWKLKLADILYCEVI
                     KRKIYVHLKKDTVDYYETIENLERSLPTNFFRCHRSYIINLQYVYGYENGNAVMESGD
                     RIPVSRLRQQIFSKVMLEFMKNRRI"
     gene            complement(2964..4271)
                     /gene="grdF"
                     /locus_tag="KRH23_003709"
     CDS             complement(2964..4271)
                     /gene="grdF"
                     /locus_tag="KRH23_003709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_082007859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:complement(3222..3224),aa:Sec)
                     /transl_table=11
                     /product="sarcosine reductase complex component B subunit
                     beta"
                     /protein_id="HHS5226973.1"
                     /translation="MSKIRVVHYINNFFAGIGGEEKADIPPEKRAGVVGPGIAFQSQF
                     NDDAEIISTVICGDTYFGENIESATQELLKMIKEESPDLFIAGPAFNAGRYGVACGTI
                     CKAVEEELNIPVITGMYKENPGVDMFKLDLHIVSTGNSAASLRKVVPIMTKLGLKLVR
                     GEEIGPPEEEGYIMRGIRKNFFHELRGSERAIDMLVKKMKGESFETEYPMPEFDRVTP
                     MKPVKDLSKIKLALVTSGGIVPIDNPDKIESSSATKYGIYDLTDMDSMSNKEFTTIHG
                     GYDRAYVLENPNLVVPLDVVRELEKEGVIGELVDYFITTTGTGTSVGNSKRFGEEFSK
                     KLLEDDVDAVILTSTUGTCTRCGATMVKEIERAGIAVVHICTVVPISLTIGANRIVPA
                     VGIPYPLGNPMLGEEESKKIRKNIVLKALNALTEDIEEQTVFE"
     gene            complement(4357..5643)
                     /gene="grdG"
                     /locus_tag="KRH23_003710"
     CDS             complement(4357..5643)
                     /gene="grdG"
                     /locus_tag="KRH23_003710"
                     /EC_number="1.21.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sarcosine reductase complex component B subunit
                     alpha"
                     /protein_id="HHS5226974.1"
                     /translation="MKLELGNIFIKNVEFGEKTEVKDGVLYISSEEIEKIVLEDERIV
                     SVNVELARPGESIRIAPVKDVIEPRVKIGDESKIFPGTINKVKTVGSGRTHVLLGACV
                     VTCGNIVGFQEGVIDMSGPTAKYTPFSKTNNICIVIKTKDGIDTHDYEEAARIAGLKI
                     GAYVGEAGREVEPDEVIVYETKPLLKQVKEYPDLPTVAYVHMLQSQGLLHDTYYYGVD
                     AKQIVPTFMYPTEIMDGAIISGNCVAPCDKVTTFHHLNNPVIHDLYKRHGKDLNFIGV
                     ILTNENVFLVDKERSSDMVAKLIEFLGVDGVLVTEEGYGNPDTDLMMNCKKCSEVGAN
                     VVLITDEFPGKDGKSQSIADATKEADAVVSCGQGNLVVHFPAMEKIIGTLDYVEMMIG
                     GYKGCLNEDGSMDAELQIIIASTIANGYNHLTARYY"
BASE COUNT         1889 a         1040 c          595 g         2293 t
ORIGIN      
        1 actgtaaata aatatgtgta ttcttctaaa aagtgatgat aattaaaata ttaactattt
       61 ttataaataa actatatagg tctattaaat tttactttta agtttttatc atcttggaga
      121 acacgataag tattatccca ttgttcgtct tcactgcttc tttcaaaaac atcatataat
      181 tgttttacat tttcattatt agaagattct ttttttctct ctaatagatt attatttact
      241 tctgaaacgt tattttcttc tttatttgtt ttttgtgctt tatttccttt taactcttga
      301 attttatttt caatctcttc tatttctttt tttaaagctt ctatttttaa tttggccgtt
      361 tcaccatcaa tacttttatc acttcttact ttctctattt catcctgtaa tgcttttttc
      421 ttttgttcta agccttgtac ctcactttga caactatcta aaccatttgt aattggtgct
      481 tgaccattta tatttccaac tttcatttta gtaacctcct catttctata tatcaaactt
      541 tctctattca aatacatgat atagcttaca aatactattt tcaatgaaat tgttctcaaa
      601 tactagcgca atgtaatgaa ataactagca atacatttat ttgaaaataa tctgatgtct
      661 tatctatact tatagcccct tgatattttt tagcaatttc ttttatattt aaaagaccta
      721 tacctgaacc acttgtataa ttatttattg gattatagct attttttatt tctatcataa
      781 aaaatccacc ctctaactta gtggaaagct ttaaatacct attttgttta tctacaactc
      841 tacaagcttt aattgcattg tcaatagcat tagcaaacac tatacatagg tcaaaatcgt
      901 tcatgttagt gctttggggt ataattactt cacaatctac ctctatgcct aattgttttg
      961 ctatacttaa tttattgttg aaaagagcat caataacaat attctgtgta ttacaagaaa
     1021 atgataggtc acttgttact ttttcaagct tatttaaata atcttgtgct tttaaaattt
     1081 ggtctttttt caacaatcca ttgacaatag ctaaatgatt attaaaatca tgtctaaagg
     1141 atatagtttg tgataatcgt gatttagctt cttcaatata gtttctttga gcatgaatct
     1201 gttgattcat aattgccctc tccttctcat cttcgagagc ttgaattagt ttcttaaagg
     1261 taaatagaga aaaaaataca catatagttc caattataga aaaaagaaaa gcttgaattt
     1321 cttcagttat agaagtattt aatagcagct ttacaatccc aagacttgta tctatattta
     1381 tatttgaact atattcaaat gattgcataa ataatattat aagcaacaat ggaatcatca
     1441 aaattgctag atatttatca aagttcataa ctttaatatt aaacttttta gaactatacc
     1501 aatatataaa tccagctatt ataatagtaa ttaaagaaga tagtcccata tttatatcaa
     1561 atttataaat atctgtattt atatcactag taaatatcaa gtaatttaat ggagctgtaa
     1621 atccatatgc taattgttca attaaatata ctaataaagt tgatactata gataaaacag
     1681 tagattgttt tattatgtac tttacaaata aaaaagtcat aagaaaaagc agaatctgtg
     1741 aagaaaataa attacataaa ttaaaatatg tatttataat gattaaaaaa attgaaatta
     1801 tcgaatataa aataaaacac caaaattttg aattaacatt tgtaaaactg attagaaaat
     1861 agtattgcac tattaccatt aaaattctat atacaataaa agaaaagaaa aaattgtact
     1921 ttaaaaataa atcggaagaa aataaattaa tcatcttata tcctcctatt tttcatgaac
     1981 tcaagcataa cttttgaaaa tatttgttga cgtagtctag aaacaggtat tctatctcca
     2041 ctttccataa ctgcattacc attttcatat ccatatacat attgtaaatt gattatataa
     2101 ctacgatgac acctaaaaaa atttgttggt aaacttctct ctaaattttc aatagtctca
     2161 taataatcta cagtatcttt ctttaaatga acataaatct ttctttttat aacttcacaa
     2221 tataaaatat cagcaagttt taatttccaa tatgaataac ctttttgtat tgtgatataa
     2281 ttactttcat tatcctcaag ttttgtaact attttatcca aagttttata tagtttctca
     2341 ttagatagag gttttatcaa ataatttata gcatctactt caaaagcatc aaatacaaat
     2401 tcatttaaaa ctgtaacgaa aattataaag cactcattac catatgacct taattttcta
     2461 gctgcctgca ttccgttaat ctcttccatc tgtatatcta aaaatacaat attaaacttt
     2521 tcatgattgc atagtaaatc ttctacttta ttaaaaagct ctatattata taataaattc
     2581 ttctgcttca tgtataattc tatattttcc tttaaatgat ttagcatata ggattcatca
     2641 tcacaaatgg caattgaaat caatatatac accttctttc ttatcattat tctaattatt
     2701 atataaagtt aattttttct gttcaattaa tatgatctaa tatgttgaat atttgttcca
     2761 aaatgtaata atctcgcttt tcatagtata tctaatttga atttgtgtat caatattata
     2821 ataaactaat ttatcacttt tataaattta atttaaaaaa atgcaaattt cgaatttacc
     2881 taataaaaaa agatatcgta aaataatttt aaaaaattat tttttgatat ctttttttat
     2941 ttcagtgttg tgttgtattt ttattattca aatactgttt gttcttctat atcttctgtt
     3001 agtgcattta aagcttttaa aactatattc tttctaattt ttttactttc ctcttctcct
     3061 aacataggat ttccaagtgg atatggtatc cctactgctg gaacaattct attagctcct
     3121 attgtaagtg atattggtac tactgtacat atatgaacaa ctgctatacc agctctctca
     3181 atctctttta ccatcgttgc tccacaacga gtacaagtac ctcatgtaga agttaaaatt
     3241 acagcatcta catcatcttc taacaatttc ttagaaaact cttctccaaa tctcttagaa
     3301 ttgccaacac tcgttcctgt tcctgtagta gttataaaat aatctactaa ttctccaatt
     3361 acaccttctt tttcaagctc tctaactaca tctagtggta caactaaatt tggattttca
     3421 aggacatatg ctctgtcata ccccccatgt atagttgtaa attctttatt tgacatagaa
     3481 tccatatctg ttaaatcgta aattccatat ttagtagcac ttgaagattc aattttgtct
     3541 ggattatcaa ttggaactat ccctccagaa gttactaggg caagttttat cttagataaa
     3601 tctttaacag gtttcatagg tgtaactcta tcaaattcag gcattggata ctcagtttca
     3661 aagctttccc ctttcatctt tttaaccaac atatcaattg ctctttcaga ccctctaagt
     3721 tcatggaaga aattttttct tattcctctc attatatatc cttcctcttc aggaggtcct
     3781 atttcctcac ctctaaccaa tttaagacct agttttgtca ttattggaac tacctttcta
     3841 agacttgctg ctgaatttcc tgtagacact atatgcaaat ctaatttaaa catatctaca
     3901 cctggatttt ctttatacat gcctgtaatt acaggaatat ttaactcttc ttcaactgcc
     3961 ttacaaatag tcccacaagc tactccatat ctacctgcat taaatgctgg gcctgcaata
     4021 aataaatcag ggctttcttc ttttatcatt tttaaaagtt cttgagttgc actctcaata
     4081 ttttcaccaa aatacgtatc tccgcaaatt acagttgaga ttatctctgc atcatcatta
     4141 aattgactct gaaatgctat tccaggtcct actacaccag cccttttttc tggcggaata
     4201 tctgcttttt cctctccacc tataccagca aagaaattgt ttatataatg aaccactctg
     4261 attttactca tctcttaatc ctccaaatca ctttatagtt attacatcaa ttagaccaat
     4321 gattacatca acagaacttt atattcaaat acttatttaa taatatcttg ctgtcaaatg
     4381 attatagcca tttgctatag ttgatgctat tataatttgt agctctgcat ccatgcttcc
     4441 gtcttcattt aagcatcctt tatacccacc tatcatcatt tcaacataat ctaaagttcc
     4501 tataattttt tccattgctg ggaaatgaac cactagattt ccttgaccac aagaaacaac
     4561 tgcatctgct tccttagtag cgtctgctat agattgactc ttgccatctt ttccaggaaa
     4621 ttcgtccgtt atcaaaacta catttgctcc aacttcacta cattttttac aattcatcat
     4681 taggtcagta tctggattcc cataaccttc ttctgtcact aggactccat caacgcctaa
     4741 aaattctatt aatttagcta ccatatcaga gcttctctct ttatcgacca agaatacgtt
     4801 ctcattagtc aaaataactc ctataaagtt taaatctttt ccatgtcttt tatataagtc
     4861 atgtataact ggattattta aatgatggaa tgttgtaacc ttatcacatg gtgctacaca
     4921 gtttccagat attatagctc catccattat ttcagttgga tacataaatg taggcactat
     4981 ctgtttagca tccaccccat agtaataagt gtcatgtaaa agtccttgtg attgtaacat
     5041 gtgaacatat gctactgttg gcaggtctgg atattctttt acttgtttta ataatggctt
     5101 tgtctcatat acaatgactt catctggctc aacttctctt cctgcctcac ctacatatgc
     5161 acctattttt aatcctgcaa ttctagctgc ttcttcataa tcatgagtat ctataccatc
     5221 ctttgttttt ataacaatac atatattatt tgtttttgaa aaaggtgtat atttagcagt
     5281 aggaccactc atatcaatta cgccttcttg aaatccaact atatttccac aagttacaac
     5341 acaagctcct aaaagtacat gggttcttcc acttcctacc gtcttcactt tatttatagt
     5401 tccaggaaat attttgcttt catctccaat tttaactcta ggctctatta catctttaac
     5461 tggagctatt cttattgatt cgccaggtct tgcaagttca acatttacac ttacaatcct
     5521 ttcatcttct aatactatct tttctatttc ttcgctacta atatatagta ctccatcttt
     5581 tacttctgtc ttttctccaa attcaacatt ttttataaat atattcccta gctctagctt
     5641 catatgaaaa tcccccttaa tatatttaat cgcaattaaa agtatttatt acgtttatta
     5701 atatataaag cattttctat gccaattatt taaaatatat attctatgta ttaatgtcat
     5761 agaaattttc atttttaatt tacaccaata ttgaatttac caataattat tgtaaat
//
LOCUS       DAEORM030000114         5701 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.120, whole genome shotgun sequence.
ACCESSION   DAEORM030000114 DAEORM030000000
VERSION     DAEORM030000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5701)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5701)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 5701)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5701
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.120"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     regulatory      472..548
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF01734"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Fluoride riboswitches increase expression of
                     downstream genes that help mitigate the toxic effects of
                     very high levels of fluoride; They are found in a wide
                     variety of bacteria and archaea; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="fluoride"
                     /db_xref="RFAM:RF01734"
     gene            897..2069
                     /locus_tag="KRH23_003711"
     CDS             897..2069
                     /locus_tag="KRH23_003711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005247 - voltage-gated chloride channel
                     activity [Evidence IEA];
                     GO_process: GO:0006821 - chloride transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HHS5226975.1"
                     /translation="MLGLIGIPVGAIIGLIDTIFGTVLLKVTDIRETYPMYLIPFLAV
                     VGVVIAYCYFKFGGKSSKGMNLIFEVGHGEEEIIPLRLVPFIISGTWLTHLFGGSAGR
                     EGVAVQIGATFSHWVGKRLPIKNASSIFLVTGMAAGFAGLFETPIAAILFAMEVLVAG
                     SLEYQSLFPAFTASFTASSVSKALGLEKFSFALSSKVVFDLSIFWKLIVLGIIFGMVG
                     GAFAWCLKLSKRKIGNRLKNPMIRIAIIGVCLSVLFLLFYKGRYSGLGTNLIQNSFYG
                     GEIYSFDWLLKFILTILTLSAGFQGGEVTPLFSIGASLGVLLAGFFNLPIELVAALGY
                     ASVFGSATNTFFAPVFIGAEVFGYSYLPYFFVVCAISYIFNMDKSIYSLQKISTKQ"
     gene            2132..3325
                     /locus_tag="KRH23_003712"
     CDS             2132..3325
                     /locus_tag="KRH23_003712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HHS5226976.1"
                     /translation="MLTSLALIFLLGMASGGIFKRIKLPNLLGMLLTGIILGPYVLNL
                     IDNSILDISSDLRKIALIIILTRAGLSLDINDLKKVGRPAVLMCFIPATFEIIGMIVL
                     APKLLGVSILEAAVMGAVVGAVSPAIIVPKMLKLMEEGYGTEKSIPQMLLAGTSIDDI
                     FVIVMFTVFTGLAQGNSISAISFLQIPVSIILGVIVGAVIGICLAVFFKKVHMRDSAK
                     GVLLLSISFLMISLETALEGIVPFSGLLAVMSIGIFLQIKYRVVARRLSIKYSKLWVG
                     AEILLFVLVGATVDISYAFKAGIGAVILIFGVLLFRMVGVFFCLIKTNLTIKERLFCM
                     IGYIPKATVQAAIGGVPLAMGMASGQLILTLAVLAILITAPLGAFGIDVTYKKLLTSV
                     KGESK"
     gene            3526..3906
                     /locus_tag="KRH23_003713"
     CDS             3526..3906
                     /locus_tag="KRH23_003713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HHS5226977.1"
                     /translation="MCLKKLSKLELVIMKFIWNLDIKTNSYEIIDYMKEEHNLPEKVA
                     LKTLSKLSKKRFLYVQETGKCMYYTVAIKEKAYLEFISRNVQNLLKNNFIRNLLVSFH
                     EEELTEEKIKSLENWVVNWEEAYV"
     gene            4218..4463
                     /gene="cdd1"
                     /locus_tag="KRH23_003714"
     CDS             4218..4463
                     /gene="cdd1"
                     /locus_tag="KRH23_003714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein Cdd1"
                     /protein_id="HHS5226978.1"
                     /translation="MGELQKIPGVGKATEKSLIMLGYTTIKSLKDANPAQMYEKECLM
                     RGQHIDRCQLYVYRCAVYFASTENPEPEKLKWWYWKD"
     gene            complement(4681..4950)
                     /locus_tag="KRH23_003715"
     CDS             complement(4681..4950)
                     /locus_tag="KRH23_003715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3795 domain-containing protein"
                     /protein_id="HHS5226979.1"
                     /translation="MFESRCGVCCDSCTKKEQVNCTGCPTMEKPFWGGECKVKTCCES
                     KELNHCGECDTFPCDMLLNKGKDQGFDPMVNIEQCRKWLEETVSN"
BASE COUNT         2107 a          633 c          937 g         2024 t
ORIGIN      
        1 gtgaagaaaa atgtttaaat tatgtattat aatataagca gagtgaagaa aaaatttaaa
       61 tcatgcatca taatataagc agagtgaaga aaaatattta aataatatat cataatgtag
      121 agtgagtaaa aatatttaaa taatatatca taatgtagag tgagtaaaaa tatttaaatc
      181 atgtatcata atgtagagtg aagaaaaata tttaaatcat gtatcataat gtagagtgaa
      241 gaaaaatatt taaataatat atcataatgt ggagtgagga aaaatattta agttatgtat
      301 cataatacaa agtaaagaaa atcatttaaa ttatatatca taaaaataat atgaagtatt
      361 gaacactcat aatattagag actttaatat tttaattgat aggttatatt atttataaca
      421 ttaaaaatac aatttacata aaatagacat atgaaaaata aaaaattata taataattat
      481 gggaatgagg ttctcccttg gatgataata tcctaaactg ccaatgagct gatgacttct
      541 atgatatcat agatgccacc agcttttttt gttgtttaaa tcgataaaat ggaggtgaat
      601 tacttactaa atttttattt tttaaatttg aagaaatatt taattaatag aaaaaatagt
      661 agattatatg ttaattattt tattaagaat gggttaagag tgtacctata tcctatcaat
      721 ttaaaaaaca attatgatag tcattacatt gactacagtt gatgcaataa aactttcaaa
      781 aaatcttatg atgcaaatgg aaaggaatta aaatgataga aaaatttaaa actttaatat
      841 ggattaaaat gataataaga attaaaagcg tttataaaac atatggtgga ctatttttgt
      901 taggactcat aggtatacca gttggtgcaa ttataggtct tatagacacc atatttggaa
      961 cggttcttct aaaagttaca gatattcgag aaacatatcc aatgtatctg ataccatttt
     1021 tagcagtagt aggagttgtt attgcttatt gctattttaa atttggagga aaaagtagta
     1081 aaggaatgaa cctaatattt gaggtagggc atggagaaga agaaattatt cctttaagat
     1141 tggttccatt tataatatca ggtacatggt taacccattt atttggtggt agtgcaggac
     1201 gagaaggagt tgctgttcag attggtgcaa ctttttcaca ttgggtaggt aaaaggttgc
     1261 ctataaaaaa tgcttctagt atttttctag taactggtat ggcagctggt tttgcaggat
     1321 tatttgagac accaatagca gcaatactat ttgctatgga ggttttggta gctggttcac
     1381 tggagtatca atcgcttttt cctgcgttta ctgcttcttt tacagcaagt tcagtatcaa
     1441 aagctttagg gttagagaaa ttttcttttg cactttcttc taaagttgta tttgacttgt
     1501 caatattttg gaagcttatt gttttaggaa ttatttttgg aatggttggt ggagcatttg
     1561 catggtgttt gaaattgtca aaaagaaaaa taggtaatag attaaaaaat cctatgataa
     1621 ggattgctat tattggagta tgtcttagtg tattattcct tttattttat aaaggaagat
     1681 attcaggttt agggacaaat ttaattcaaa atagtttcta tggtggagaa atttattcat
     1741 ttgactggct gttaaagttt atacttacaa tactgacttt gtcagcaggt tttcaaggag
     1801 gagaggttac acctttgttt tccattggag ctagtcttgg tgtattgtta gcaggatttt
     1861 ttaatttgcc aattgaatta gttgcagcgc ttggctatgc tagtgtcttt ggtagtgcta
     1921 caaatacttt ttttgcacct gtatttatag gggcagaagt ttttgggtac agctatttac
     1981 cttatttctt tgtagtatgc gctatttcat atatatttaa tatggataaa tctatttatt
     2041 cactacaaaa aatttcaaca aaacaataaa taaaacaaca taatgtatga ttagaagaga
     2101 aagaatatta gagaaaggat agggtaggaa tatgttgaca agtttagctt tgattttttt
     2161 attaggaatg gcctcgggag gtatttttaa gaggataaag ttacctaact tattgggaat
     2221 gttacttaca ggaattatat taggtccata tgttttaaat ttgattgata attcaatact
     2281 agatatttct tctgacctta gaaagattgc attgattatt atattaacaa gggctggatt
     2341 atctttagat ataaacgatt tgaagaaagt gggaagacct gctgtactta tgtgctttat
     2401 tccagctact tttgaaatta tcggaatgat agttttagca ccaaagttac taggcgtttc
     2461 tatattggaa gcagcagtca tgggtgcagt agtaggagca gtttctcctg caattattgt
     2521 acctaaaatg cttaaattaa tggaagaagg ttatggtaca gaaaaaagta ttccacagat
     2581 gcttttagca ggaacttcta tagacgatat tttcgtaatt gtgatgttta cagtattcac
     2641 aggattggca caaggaaata gtatatcagc tattagtttt ttacaaattc cagtatcaat
     2701 tatattaggt gtaatagttg gagcagtgat tggaatctgt ttagcagtat tttttaagaa
     2761 ggttcatatg agagattctg ctaaaggggt gttgctttta agtatctcat ttttaatgat
     2821 aagtttagag actgctttag agggtattgt gccattttct ggattattag cagttatgag
     2881 tattgggatt ttccttcaga taaaatatcg tgtagttgca agaagattgt ccataaagta
     2941 ttcaaaacta tgggttggcg ctgaaattct cttgtttgtt ttggtagggg caacagtaga
     3001 tataagttat gcatttaaag caggaattgg agctgtaatt ttaatatttg gagttctttt
     3061 attccgtatg gtaggagtat tcttctgcct tattaagaca aatttgacaa taaaggaaag
     3121 gttgttctgt atgattggct atattccaaa ggctacagta caggcagcaa taggaggtgt
     3181 accacttgca atggggatgg catctggaca acttattttg acgttagcag ttctagctat
     3241 acttataact gcacctcttg gagcttttgg aattgatgta acttataaaa aattattaac
     3301 ttctgtaaaa ggcgagagta agtaaaaata aagattattt taagtggtaa gttatatttt
     3361 ggaaaaggat tatactattg aatacaatat aaaaaaatca tttgggagat taagaaggta
     3421 gaagttaaga acagatttta aggtatgtta tgattattag aattgatttt gtgaaattat
     3481 tattgtaata tttaattata tagataaaga agcggagtga taactatgtg tttaaaaaaa
     3541 ttatcaaaat tagagttagt tattatgaaa tttatttgga atttagatat aaaaaccaat
     3601 tcatatgaga ttattgatta tatgaaagaa gaacataatt taccagaaaa agtagcttta
     3661 aaaactttat caaaactatc aaagaaaaga ttcttatatg ttcaagaaac aggcaagtgt
     3721 atgtattata cagttgcaat aaaagaaaag gcatatttag agtttatatc aagaaatgtg
     3781 caaaatcttt tgaagaataa ttttataagg aatttattag tatcatttca cgaagaggag
     3841 ctaacagagg aaaagataaa gtcgttagaa aactgggtag taaattggga agaagcttat
     3901 gtataatatg atttgttgtc taaaaagagt tttgtaatag tttatctaca attataaaac
     3961 tctttttaaa tgtgtagatt taatttaaaa taatttgcta ttagcagaat aaaaaataaa
     4021 tatattattt tatttgtata aaactgtatt atgatgtaat taagtgactc agtactttag
     4081 aggtagtaaa atatacatat atgaaaaagc ataaataaat tgatatgata taataaaaaa
     4141 ttaaatatta actataataa aaaaatatct gggactaagt ataatacaaa aagaatatac
     4201 cagaaagaag gtgaagtatg ggagaactac aaaaaattcc aggggtaggg aaagcaacag
     4261 aaaaatcttt aatcatgtta ggatatacaa ctattaaatc acttaaagat gcaaacccag
     4321 cacaaatgta tgaaaaggaa tgtttaatgc gtggacagca catagacaga tgtcagttat
     4381 atgtatacag atgtgcagta tattttgcat caactgaaaa tccagaacca gaaaaattaa
     4441 agtggtggta ttggaaagat taaaaaatca aaaaagttag acataaaaaa gagttgaata
     4501 tccgttttaa ataataaaaa ctaatactca actctttttt agtcgtaaat tttatgtaaa
     4561 tctatttgta tggctaaata tacccatcaa taaatgtata aatataccaa tcaacaaatg
     4621 actaaacata ctacctaaca aaggattaaa taaattactt aacaaagcat tttaaaacaa
     4681 ttaattagaa actgtttctt caagccattt tctacattgc tcaatattta ccatagggtc
     4741 aaaaccttgg tcttttccct tatttaaaag catatcacaa gggaaagtat cacattcacc
     4801 acaatgatta agttccttac tttcacagca agttttaacc ttacattctc caccccaaaa
     4861 tggtttttcc atagttgggc aaccagtgca atttacttgt tctttttttg tacaactgtc
     4921 acaacagaca ccacatcttg attcaaacat gttcaaacat cctttccatt atttaaaaat
     4981 attataaaat gattttagat gaatacaaaa gtgcaaatag ttgattttag gtcatctaaa
     5041 tgttaaacct aaaattatta gtactggtaa atttataaaa actattccaa aaatcttttt
     5101 gaatatttca aaacacaata aattacttca aatccctttg aatatatttt acagcattat
     5161 agattgcttt aaatctcttt gagtattcta caagactata gattagttta aatccctttg
     5221 aatatatttt acaacattat agattgtttt aaatctcttt gaatattcta caagactata
     5281 gattagttta aatccctttg aatatatttt acagcattat agattgcttt aaatctcttt
     5341 gaatattcta caagactata gattagttta aatccctttg aatatttcaa aacaccatag
     5401 attactttaa attcctttga atattctata acactataaa ttacttttaa cttttatata
     5461 accataaagt ttttatctgg cactttaaat ggagttttat atcaaatttg ccttccatcg
     5521 aataaccaaa cttaatttaa ttacacattt caagagtcaa atattcattc aatatatttg
     5581 ataattctat gttatagcta taattaaata tagattatta aagttaaata tttatttaat
     5641 atattgaatg attttttacc tatatttaat taagcttcat tatataatat aaaaattgtt
     5701 t
//
LOCUS       DAEORM030000115         5628 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.121, whole genome shotgun sequence.
ACCESSION   DAEORM030000115 DAEORM030000000
VERSION     DAEORM030000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5628)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5628)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 5628)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5628
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.121"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            240..1067
                     /locus_tag="KRH23_003716"
     CDS             240..1067
                     /locus_tag="KRH23_003716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AIM24 family protein"
                     /protein_id="HHS5226980.1"
                     /translation="MDLSKKVKILENASDGKSEFEILEFEKLEGASSPLMAMGLYFAR
                     EAGLKARQIKIKLNNSSIKTEAGALYYYKGNISSETKIGGVGGLFKKGISGALTNESM
                     MKPVYKGTGEVYLEPSFRHYLFMSLDNDSIIVDKGLFYCCSDTIEVKAFTQKNFSSAL
                     LGGEGFFQIELSGTGVIVLECVVPQSEIVEYELKNGEELKVDGNFAIARTSGVNFSVT
                     KSDKSLIGSALNGEGFLNTFTGNGTVWLAPTQVMYEKLSFGAMPTNDNMNNKVSKQK"
     gene            2090..2554
                     /locus_tag="KRH23_003717"
     CDS             2090..2554
                     /locus_tag="KRH23_003717"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HHS5226981.1"
                     /translation="MNLNKVKFTEEHAIEVTNWKYEGKYSIYNLPPWEEIKKKNFSLA
                     KEDKRKNFISFINDNKELIGFINLLDEGSSVFFGIGMKPNYCGMGIGKEIISLGLQEC
                     RNKYSTKPIVLNVRTWNMRALKCYESQGFKIVETKVQKTHLGDGEFFVMRYQ"
     gene            complement(2821..3465)
                     /locus_tag="KRH23_003718"
     CDS             complement(2821..3465)
                     /locus_tag="KRH23_003718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHS5226982.1"
                     /translation="MFGQSFQNCLVLIKENFKLSTLTNLICSIILLCMIPLIQGVANL
                     DRISTAICLENYVAIIGIVMLVPVFSLEQSKEIDEIVSSKALSQVIVQLIRILMSIIG
                     IVVLIIGFVNVLIYLGCNFPVVEYIIGSFASAMFIGSLGMFFSNLFNNTIIGYMISIG
                     YLILNMMTKGKYVGKFFIMSMSQGSFDEKYWLILGSVVLIIASLLIKPVKRKIR"
     gene            complement(3395..4684)
                     /locus_tag="KRH23_003719"
     CDS             complement(3395..4684)
                     /locus_tag="KRH23_003719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHS5226983.1"
                     /translation="MNLFIKECKNILKSMVYYIFIVVLVFFYISQLGSSVSNDVSKNI
                     PNDGNPLVAPQKVENIEEYYSVHNQYPYGQKESMKTEKVIPNATINLIREYQKNTYTT
                     YPTGVVKYIKLDQNKTKTIEKYIEEITGKSISEINSLWKTDESIKIDYSKVSLERFEE
                     IMQRVDDILGGGSAYAFDKLQRFGVVPVTYDEAMKNYNYTIQKDKVSNGYARIFCDYI
                     GIVLSIFPVFVAVFMSLKDKRSRMREIIYSKQVSSCKIVLSRYFALVFMMILPVLILG
                     MKDLLPLIFFAKDKGISIDNLAFIKYTLWWILPTLMIVTAVGMSITILTDTPVAIIVQ
                     LIWWLYSINSTGLKGDYSTMGLMIRHNSVLNGDIIIQNFNQIMINRIVISLGALVLVL
                     LAIFLYEQKRRGNLDVWAKFSKLFSSNKRKLQIKHFN"
     gene            complement(4681..5553)
                     /locus_tag="KRH23_003720"
     CDS             complement(4681..5553)
                     /locus_tag="KRH23_003720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHS5226984.1"
                     /translation="MEMKIAVSNLSKRFGKKQALDNINLEIDSGMFGLLGRNGAGKTT
                     FMRILATLLSKTEGSIHMCGVPIENTKEIRNMVGYLPQDFSMYPNMTVYKAMDYLAVL
                     SDIPLRKRRKIIAKLLSKVNLTNYQNVKVKSLSGGMNRRLGIAQALIHNPRVLIVDEP
                     TAGLDPEERIRFRNLLCEIANDRIVILSTHIVGDIEATCENVAILNSGKVIYNGSTEA
                     LAKLAEGKVYSIEVDKKDIENIKSRFIVIGMLTHGGKAILRIISDDKPFETAVNCNPT
                     IEDGYMLIMGGDNI"
BASE COUNT         2038 a          780 c          700 g         2110 t
ORIGIN      
        1 ataattttaa catgcccata aaatataata cccacaaatg ataaataata ctcaaaatgt
       61 ctattgaaat aactatacat ccttaaataa cttaacttaa atctaaacat ttcaaaaact
      121 tcttaaaaat atgtaaaaat ttgatgataa agtagcgatt ttttcaaaaa aaatgtaata
      181 tagagttata tcttataata ttttagagat aaattttatc atagtgggga gaaatttata
      241 tggatttaag caaaaaagta aaaattttag aaaatgcatc agatggcaaa agcgaatttg
      301 agatattaga atttgaaaaa cttgagggag cttctagccc attaatggca atgggattat
      361 attttgctag agaagctggt ttgaaagcta gacaaattaa gataaaatta aataattcat
      421 caataaaaac agaagctggt gcattatact attataaagg aaatatatct tctgaaacta
      481 agattggtgg tgttggaggt ctttttaaaa aaggaatatc aggagcactt actaatgaat
      541 caatgatgaa acctgtatac aaaggtactg gagaagttta tttggaacct tcttttagac
      601 attatttatt tatgagtctt gataatgatt ctataattgt tgataaggga ttattctatt
      661 gttgctctga tacaatagaa gtaaaagcat ttacacaaaa gaacttctca tctgctttac
      721 ttggtggtga aggcttcttc caaatagaat taagtggtac tggtgtaatc gttctggaat
      781 gtgttgtacc tcaaagtgaa attgtagagt atgaattgaa aaatggtgaa gaattaaagg
      841 tagatggtaa ctttgcaata gcaagaacat ctggtgttaa tttttctgtt acaaaatcag
      901 ataaatcttt aattggttct gctttaaatg gtgaaggttt cttaaataca tttactggta
      961 atggtacagt ttggctagct ccaactcaag taatgtatga aaaactaagt tttggagcaa
     1021 tgcctactaa tgataatatg aataataaag tttctaagca aaaatagttg ttttataaat
     1081 atttattaaa tcattattga ttttataaag tcactataaa ttttattaga ttattattat
     1141 aaaatcagag tgtggaaatg tttatgtgta ttctttaaat aaaaatttcc acattctgta
     1201 aggttattat acttgatata taaaattcaa tttaggaaca tagtctaaca tttataaaca
     1261 tattaaggta atgatttctc ttagtaatta ttctcatatc ttattctttg attatattta
     1321 tcttattcct agcccttatg tcatattata tttcttatct tattatttat aattagcatt
     1381 aacttatcta aaatcttgta tttttttaat agtaaagttt acatctatat taaaaagttt
     1441 acatctatat taatttcata aaacaatcaa ggtagtcaag agattcaact ttacttgatt
     1501 ttaaaaattt aagtgaattt gttcttatac acaccttttt aaaattatat ctgtagaaaa
     1561 tatcatttag agccataatt aaattaactt attaaatttt agaaaattta ttaaaaaata
     1621 taagttaaat taatattttt aaagattctt ttttgtaact actagaatac taatttagta
     1681 gttattgtat ctctaaagtt taagcatgga tagatataca tttgataatt tgcctataat
     1741 ttacctacta cttggagtat tggagcaaat acaatatatt aataataagt tcctaaagcc
     1801 aataaattaa ctaatacaca taaagatatt gatgttgatt atacaactat aagaaacgga
     1861 tttaacagaa tttaatcaag ctaagaaatt atatatatcg tgatgttttt gaattagaag
     1921 gtaattcaaa attagtttat agtcttctat gaatccaata aaaagtacag ggtacaagaa
     1981 ttgttagtaa aatttttaaa gattttatgg ataaatataa atagttttac ttattttcta
     2041 aaactttaaa ataccattaa ttaccttaaa tattttcata ggaggacata tgaatttaaa
     2101 taaagttaaa tttactgaag aacatgctat tgaagttact aattggaaat atgaaggtaa
     2161 atattcaata tacaatctac ccccatggga ggaaattaaa aagaagaatt tttcactagc
     2221 aaaagaagat aaaagaaaaa attttataag ttttataaat gacaataaag aattgatagg
     2281 ttttataaac ttattagatg aaggaagctc tgtattcttt ggtattggta tgaaaccgaa
     2341 ttattgtgga atgggaattg gtaaagaaat aattagccta ggattacaag aatgtagaaa
     2401 taaatatagt actaaaccaa ttgtattaaa tgtaagaacc tggaacatga gagctttaaa
     2461 atgttatgag tctcaaggat ttaaaatagt tgagactaag gtacagaaaa cgcatttagg
     2521 agatggagaa ttttttgtta tgaggtatca atagtttata acaatagtct tattgttaat
     2581 acaacaatta aaataaaaaa atacatatgt gtaggtcata gcaataagtg tctttgaaat
     2641 ataaatttga gagcttttga taaaatttgg tatacatata tattttatac tacggatata
     2701 taaatctatc tacatacata aagagattgt aagtaggttt gtgtatataa aaatagattt
     2761 atatttcata aatgtacctt ttatttgtat tacctttatt ttatctaagc tctcatttta
     2821 ttatctaatc ttccttttta ctggttttat taagagagat gcaattatca acacaacact
     2881 tccaagtatc agccaatatt tctcatcaaa actaccttga ctcatagaca ttataaaaaa
     2941 ttttccaaca tacttgcctt tagtcatcat atttaaaatt aaatatccta tagatatcat
     3001 ataacctatg attgtattat taaataaatt tgagaaaaac attcctaaac ttcctataaa
     3061 catagctgat gcgaaacttc caataatata ctcaactact ggaaaattac atccaagata
     3121 tattaaaaca tttacaaaac ctatgattaa taccactata cctataattg acatcagtat
     3181 cctaattaat tgtacaataa cttgagataa tgcttttgaa gatactatct catcaatttc
     3241 ttttgattgc tctagcgaaa atacgggtac caacattact atccctatta ttgcaacata
     3301 attttctaaa catatagctg ttgaaattct gtctaaatta gctactcctt gtattagagg
     3361 aatcatacat agcaatataa ttgaacatat taaattagtt aaagtgctta atttgaagtt
     3421 ttcttttatt agaactaaac agttttgaaa actttgccca aacatcaaga ttcccccttc
     3481 ttttttgctc atataagaat atagctaaca aaacaagcac caatgctccc aagcttatca
     3541 caattctatt aatcataatt tgattgaagt tttgtataat aatatcccca tttaatacac
     3601 tattatgtct tatcattagt cccattgttg aataatcacc tttgagtcct gtagaattta
     3661 tactgtaaag ccaccaaatt aattgcacaa taattgctac tggtgtatct gttaatatag
     3721 taatactcat tcctacagct gtaactatca taagagttgg tagtatccac cataatgtat
     3781 attttataaa tgctaagtta tcaatagata tacctttatc tttagcaaag aaaatcaaag
     3841 gaagtaaatc tttcatacct aaaattaata caggcaatat catcataaag acaagtgcaa
     3901 aatatcttga taaaactatt ttgcatgaag atacttgttt tgaataaata atctctctca
     3961 ttcttgaacg cttatcttta agtgacataa aaactgccac aaatactgga aatatactta
     4021 aaactatacc tatataatcg caaaaaattc ttgcataccc attactaact ttatcttttt
     4081 gtattgtata gttgtaattc ttcatagctt catcataggt aactggaact actccaaatc
     4141 tttgtaactt gtcaaaagca tatgcagacc ctcctcctaa aatgtcgtct actctttgca
     4201 ttatttcttc aaatctttca agagatactt tagaataatc tatttttata ctttcatcag
     4261 ttttccaaag tgaatttatt tcgctaatac ttttaccagt tatttcttct atatattttt
     4321 ctatggtctt cgttttattt tggtctaatt ttatatactt aactacacct gttggatacg
     4381 ttgtatatgt gtttttttga tattctctaa ttaggtttat agttgcattt ggaatgacct
     4441 tttctgtttt catagattct ttttgaccat atggatattg attgtgtaca gagtaatatt
     4501 cctcaatatt ctctactttt tgtggagcaa ctaatggatt tccatcatta ggaatatttt
     4561 tacttacatc atttgaaact gaacttccaa gttgagaaat atagaaaaaa actaaaacta
     4621 caataaaaat ataatatacc atactcttta atatattttt acattctttt ataaatagat
     4681 tcatatatta tctcctccca ttataagcat atagccatct tcaatagttg gattacaatt
     4741 tactgctgtc tcaaaaggtt tatcatctga tataatccta agtatagcct ttccaccatg
     4801 agtcaacatt cctataacta taaatctact ttttatattt tcaatatctt ttttatctac
     4861 ttcaatacta tatactttcc cttcagctag ttttgctaat gcttctgttg agccattgta
     4921 tatgactttt ccactattca atatagctac gttttcacat gtagcttcta tatctccaac
     4981 aatatgtgta gataaaataa cgattctatc atttgcaatt tcgcatagta aatttctaaa
     5041 tcttatacgt tcttctgggt caagacctgc tgtcggctca tctactatta aaactctggg
     5101 attatgaatt aatgcttgtg ctatcccaag ccttctattc atacctccag ataaagattt
     5161 tactttcaca ttttgataat tagtaaggtt tactttgctt aataactttg ctataatttt
     5221 tcttcttttt cttagtggta tatccgataa aactgctaaa taatccattg ctttatatac
     5281 tgtcatgtta ggatacattg aaaaatcttg tggcaaataa ccaaccatat ttctaatttc
     5341 cttagtattc tcaataggaa ctccacacat atgtattgaa ccttctgttt ttgataataa
     5401 agtggctaaa attctcataa atgtggtttt tcctgctcca tttcttccta aaagaccaaa
     5461 cataccactg tcgatttcaa gatttatatt atcaagtgct tgttttttcc caaatctttt
     5521 gctaagattg gatactgcta ttttcatttc catatataaa tacaccccca gaaacaattt
     5581 tatagaattt tatttttata aatttttact gtattttcat aataaatt
//
LOCUS       DAEORM030000116         5626 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.122, whole genome shotgun sequence.
ACCESSION   DAEORM030000116 DAEORM030000000
VERSION     DAEORM030000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5626)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5626)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 5626)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5626
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.122"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            45..164
                     /locus_tag="KRH23_003721"
                     /pseudo
     CDS             45..164
                     /locus_tag="KRH23_003721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888399.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
     gene            291..1193
                     /locus_tag="KRH23_003722"
     CDS             291..1193
                     /locus_tag="KRH23_003722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005247 - voltage-gated chloride channel
                     activity [Evidence IEA];
                     GO_process: GO:0006821 - chloride transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HHS5226985.1"
                     /translation="MLPQDYYGLIVILGVILGVMGAFYNWFTLYVQSLYKKIPKIGTF
                     GKLLIPFIMAGILGLVMPDVLGSGHNLVEELTSHEYIFGMVVLIFVIRFIFSAVSFGS
                     GAPGGIFFPLLVLGAFIGGIFGMVGVKVFGMNPDYVNNFVLLAMAGYFTAIVRAPLTG
                     IILIFEMTGSVSQMLSLSVISIVAYIVATLMKSKPIYESLLERLLEKNGEPVHKDRGE
                     KILDQFSVMFGSPVANKAIQDVQWPENCLLVAIQRGGEEIIPRGKTILRPSDVIVTMT
                     DERDSGAVYDKMENLCKEHTAHIF"
     gene            1805..2818
                     /locus_tag="KRH23_003723"
     CDS             1805..2818
                     /locus_tag="KRH23_003723"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M56 family metallopeptidase"
                     /protein_id="HHS5226986.1"
                     /translation="MVSSFLNDIFRTILVSCIFIVILLVFRITLFKIFSKKFNYYIWL
                     IVIIKLSLPFMNYTFIFNESKYNGNINKISLGNFNSISIVYSTVLVSVWIAITIFYLV
                     YTLLKYIKLKNMINDLSYDVEDDKIKNLYENLLKELKINKKIRLKYSYEVESPVFFNS
                     CVILPPCDYTLKELNWIFRHELMHFKSKDLYIKYLVIFLKCVYWFNPFVYIMEKFIDL
                     DCEFYCDERVLKNCTIEEKQDYALTIISAMRKGSNSSNKFVAGLHKESDIKKRVFSMF
                     NEKYRNGILIAVILCLLSSITYFKIDLITTKSIFYPLSKQTPIENRTNSKPTYQVNVY
                     IDN"
     gene            3170..3739
                     /locus_tag="KRH23_003724"
     CDS             3170..3739
                     /locus_tag="KRH23_003724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GrpB family protein"
                     /protein_id="HHS5226987.1"
                     /translation="MRKKLEDMTLEELWNLFPIFLTTHKECWKNWFKEEQYRLTGILP
                     MQKIVRISHIGSTSVSTIYAKPIVDILIEIIPDYNMKDIKDLIESNGYICMSESSSRL
                     SLNKGYTVDGFEERVFHLHIRYVGDNDELFFRDYLIDHPDVAKEYEKFKLDLWKKYEH
                     NRDAYTDSKLDFVREFTEKAKVLYSNRYN"
     gene            complement(4075..4962)
                     /locus_tag="KRH23_003725"
     CDS             complement(4075..4962)
                     /locus_tag="KRH23_003725"
                     /inference="COORDINATES: protein motif:HMM:NF025854.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HHS5226988.1"
                     /translation="MVNIKQYLSNKIWIFIDMVCISSFLSILIAIILPPTNLIPMGSN
                     KNIILGNLPYGTYLIILSAILANIGVILLLQPLIENVKMKIEKQANHLKEKYYNLLEN
                     QQIQIRKMRHDMNNHFQMIESYLEIEDIAGAKKYFNQLKIGIGTLSGKQFCKNQALNS
                     ILNLRHTSLEENGVDVHFNIDIDNHLGIEPIDLCTIFSNSLDNAIEASLKIPDLSNRK
                     VVLKARCEKEYFSYLLTNNKVNPINRKQELFISDKKDSNSHGYGIENIREIVNKYNGK
                     LDISYTESEFSLFLYIRLF"
BASE COUNT         2094 a          560 c          922 g         2050 t
ORIGIN      
        1 atataaaacc ttctaaataa ttgttttaaa taattacatt tgttaacatt attataagag
       61 aatggatttg tcctagttgt aatgaaactc acgatagaga tataaatgca agtataaata
      121 tattaaaaga aggattaaga ctaataacaa ttcaaaataa ataacttatg taagaaccgt
      181 aggaactacg gggatagcct gtggagaatt agtaagacat atgttagtat gcaaaattct
      241 atgaagcagg aaccctgtga ctttagtcat gggaggttca gattggaaat gtgttgccac
      301 aagattatta tggattaata gtgattttag gtgttattct tggagttatg ggggcatttt
      361 acaactggtt tactctatat gtgcagtctt tatacaagaa gattcctaaa attggtacct
      421 ttggaaaact gttgattcca tttataatgg ctggtattct tgggcttgtt atgcctgatg
      481 ttctggggag tggacacaat ttagttgaag aacttacaag tcatgaatat atttttggaa
      541 tggttgtttt gatttttgtt atacgtttta tattttcggc tgttagtttt gggtcaggtg
      601 caccaggggg aatatttttt ccattgcttg ttttaggagc atttataggt ggaatatttg
      661 gtatggtagg tgttaaagtt tttggaatga atcccgatta tgtaaataac tttgtgcttt
      721 tggctatggc aggatatttt acagctattg tgcgtgcccc tttgactggt atcatattaa
      781 tttttgaaat gacaggttct gttagtcaaa tgctttcact atcagtaatt tcaattgtgg
      841 catatattgt ggctacactt atgaagtcta aacctattta tgaaagtctt cttgagaggt
      901 tacttgaaaa aaatggagaa cctgtacata aagatagggg cgaaaagata ctagaccagt
      961 tctctgttat gtttggctct cctgttgcga acaaggcaat tcaggatgta cagtggcctg
     1021 aaaattgtct tttggtagca attcaaagag gtggagaaga aattattcct agaggtaaga
     1081 caattcttag accaagtgat gtaattgtga ctatgacaga tgagagagat agtggtgctg
     1141 tgtatgataa gatggaaaat ttgtgtaaag aacatacggc acatattttt tagggagaat
     1201 gatgaatgtt taataatgat agaatattta atgaagattt gattaaaaaa ttggtaattt
     1261 gaaagagagt taaggaatta atataagaaa atgaaaatgt gatatcttag atgtaaaaga
     1321 gtttgaagaa aataattgta tatatttgtt aatgagatta tatggactaa tggtatattt
     1381 atactgtgct aaaagttgta ctattgtatg aggaatggga ataaagggtt tgaaaaaata
     1441 ggtagaagat ttttcagata ttcttattgg gatattttaa ttaatatatt ttaattgcga
     1501 tattttggga agaatagaat ttatttataa atgaaaataa ttaaaagggg ttaaggttgt
     1561 attagcccct tttgcttata gagtttggaa atggtatctt gatagcagtt gtttcatgct
     1621 tattatattt tattacatat tttaaaattg accttattac tcctaaatca ttgttctatc
     1681 aacttttaaa acactttcaa gacaatcgcc tattgaaaac aaagttaatt aaaaacctac
     1741 atatcagttt agtattcgtg tagatgatta tataaatata aaagtataag aaaggtgagt
     1801 atctgtggtt agttcatttt taaatgatat ctttagaaca attttagtaa gttgtatttt
     1861 tatagttatt ttattagtct ttagaataac tttatttaag attttcagta aaaaatttaa
     1921 ttactatata tggcttattg tgattattaa gctatcatta ccatttatga attatacttt
     1981 tatatttaat gagtcaaaat ataatggtaa tattaataag ataagtttag gcaattttaa
     2041 tagtatttct attgtatata gtactgtttt agtctctgtt tggattgcta ttacgatatt
     2101 ttatttagtt tatactttat tgaaatatat taagcttaaa aatatgataa atgatttgtc
     2161 ttatgatgtt gaggatgata agataaaaaa tctttatgaa aatttattaa aagagcttaa
     2221 gataaataaa aaaatacggc ttaaatattc atatgaagtt gaaagtccag tattttttaa
     2281 ttcgtgtgtc attttaccac catgtgatta tacattaaaa gagttaaact ggatatttag
     2341 gcatgagttg atgcatttta agagtaaaga cctttatatt aagtatttgg tgatattttt
     2401 aaaatgtgtt tattggttta atccttttgt gtatataatg gagaagttta tagatttgga
     2461 ttgtgaattt tattgtgatg aaagagtttt gaagaattgt acgatagaag agaagcagga
     2521 ttatgcattg acaataatta gtgcaatgag aaaaggttca aatagttcaa ataaatttgt
     2581 ggctggatta cataaggagt cagatattaa aaaaagagtg tttagtatgt ttaatgaaaa
     2641 gtacagaaat ggtattttga tagcagttat tttatgttta ttatcttcta ttacatattt
     2701 taaaattgat ttaattacta ctaaatcaat attttatcca ctttcaaaac aaacacctat
     2761 tgaaaacaga actaattcaa aacctacata tcaggttaat gtttatatag ataattaaaa
     2821 aatacaaagt ttaacaagag attaatataa ataattttaa taagtatctt tcacatatgt
     2881 taaatttact ttaattatat taaagccaat gaattattct ttagaagctc caatgccagt
     2941 aaatacaggt aaagaaaaaa ttactacaat tgtagattaa aaatgttcta atatttaaag
     3001 aaatgcaaaa gtgtaagaag ggtaaaaatc tgttataata cattaaaaac taaatttaga
     3061 aaaatttaca taattagaaa aatgatttga taaaaaataa agttaaatat taactaagta
     3121 aatttgaaaa agaaaaaata taaagtacaa atttaaaagg aggtaactaa tgagaaagaa
     3181 gttggaagat atgactttag aggagttatg gaacttgttt cctatatttt tgactactca
     3241 caaagaatgt tggaaaaatt ggtttaaaga agaacaatat agactaactg gaatattgcc
     3301 aatgcaaaaa attgttagaa taagtcatat tggaagtact tctgtgagta cgatttatgc
     3361 caagcccatt gttgacatac tgattgagat aattcctgat tataatatga aagatattaa
     3421 agatttgatt gagtcgaatg gatatatttg tatgtctgag agcagtagta ggctttcact
     3481 taataaaggg tatacagtag atgggtttga agaacgagtt tttcatttgc atataaggta
     3541 tgtaggtgat aatgatgagt tgttttttag agattactta attgaccacc cagatgttgc
     3601 aaaggagtat gaaaaattta agttggacct ttggaagaag tatgagcata atcgtgatgc
     3661 ttatacagat agtaaactag attttgttag ggagtttact gaaaaggcaa aggtgttgta
     3721 ttctaataga tataattaga aataggtaca attagatatt tatcttatat attgtattat
     3781 attttttaag aaagtaatta atagaaaaag ggcttgtttc aaaatggaga gataaatccc
     3841 tttttcattg ttgaaaggat aaaaatatat ttgatttcat gtaaaaaaga gtgcctcatc
     3901 aactaaaaag tttattttga gacacacaca tttttactaa ggtaaataaa atatcacatt
     3961 tgattaaatt ttaagttaat gaatatatgt gtaaatattt aattataagt tattataatt
     4021 ttacatagta tcaaacaatc taatttgtat tatataagat aatctaattt tagactaaaa
     4081 taatctaata taaagaaata aagaaaattc actctcagta taagagatat ccaattttcc
     4141 attgtactta ttaacaattt ctctaatatt ctcaatacca tatccgtgag aattactatc
     4201 ttttttatct gaaataaata gttcttgttt tctattgata ggatttactt tgttgtttgt
     4261 caataaatag ctaaaatact ccttctcaca acgtgccttt aataccactt ttctatttga
     4321 caaatcagga attttcaaag atgcttctat agcgttatct aaagaatttg aaaaaatagt
     4381 acataaatct ataggttcta tacccaagtg attgtctata tctatattaa agtgcacatc
     4441 aacaccattt tcttctaaac ttgtatgacg aagatttaaa attgagttaa gagcttggtt
     4501 tttgcaaaat tgtttgccac taagagtacc tatacctatt tttaactgat taaaatactt
     4561 tttagctcca gcaatatctt caatttctaa atacgattca atcatttgaa agtgattatt
     4621 catatcatgt ctcattttgc gtatttgaat ttgttgattt tctagtaagt tatagtattt
     4681 ttcttttaga tgatttgctt gtttttctat cttcatcttt acattttcaa tcaatggctg
     4741 taaaagaagt atcacaccga tatttgccag aattgctgac aagatgatta gataagtgcc
     4801 ataaggtaag ttgcctaaga taatattctt attactaccc atagggatta aattagtagg
     4861 tggcagaata atagcaatca atattgataa aaatgaagat atacatacca tatcaataaa
     4921 aatccatatt ttatttgata agtattgttt tatattgacc aatctattct ttaggaaaat
     4981 atgtattaaa aaccaaaata ataatttaat tagagcagaa attatctgga ctattgaaag
     5041 tattaaaata tactcttttg agtgtataag ttcctcatat atagggttgt ttataaagag
     5101 aaaattaagc ccaattataa taggataaag tatcatgaca actgatatta taggaattaa
     5161 tttgctttta ctacatatta taagtagtat aaaatatccg aatagtgtaa acaaaatatt
     5221 tacggggtcg gaaagccata ttatcatttg actaataata gagtagccca aaatcaatat
     5281 gattttgaaa atccaatgat tcctaaagtc tataaaatag gaagtcaact tataaagaaa
     5341 aaaggctatg aaaatattga ttaatattag aataaaattt atgcttgtag agattaaaga
     5401 ataagtgccc atttaatata cctttctatt aattaagatt ctggaaacta agttttaaaa
     5461 aattaaatct taaaaattaa aattctggaa attagatttc aaagaattga ttttgaaaaa
     5521 taaaattcta gaaattaagc ttcaaaaaat tgagttttaa aagattgaaa ttttaaaaat
     5581 taagtttcaa aaaattaaat ttgaaaaaaa ctctaaaaac taagct
//
LOCUS       DAEORM030000117         5347 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.123, whole genome shotgun sequence.
ACCESSION   DAEORM030000117 DAEORM030000000
VERSION     DAEORM030000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5347)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5347)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 5347)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5347
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.123"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            complement(204..1388)
                     /locus_tag="KRH23_003726"
     CDS             complement(204..1388)
                     /locus_tag="KRH23_003726"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008483 - transaminase activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HHS5226989.1"
                     /translation="MLSKRLNFITPSYTIGISSKVKEIESNGVKVINLSIGEPDFNVP
                     NNAKSYGIDSLNKDYTKYDLVPGLKILREEICKKLIEENNCNYSIDEIVVSSGAKNSI
                     TNTLLALTDEGDEVLLPKPYWVSYPEMIKLVNAVPVFIDTKKENGFKLTKEELEKSIT
                     DKTKILVINNPSNPTGSVYTKDELIEIVDVCIQNKIYILADEIYEKICYTGEFTSIAS
                     LSEEAKDITITINGFSKSAAMTGLRLGYTASNKTIAKAMSSIQGHLISHPSLTAQYIA
                     YGALKDCSIDIDNMVKTYKSRRDLIKSKLDSIDNVGYVNPNGAFYIFIDLSKVSEKFE
                     YKDSFSIEFCNQFLEEYNVAVVPGIAFGMDKYIRISYACSENTFLSGLDKLKEFVYKI
                     MA"
     gene            1761..4112
                     /locus_tag="KRH23_003727"
     CDS             1761..4112
                     /locus_tag="KRH23_003727"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008998 - ribonucleoside-triphosphate
                     reductase (thioredoxin) activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside triphosphate reductase"
                     /protein_id="HHS5226990.1"
                     /translation="MVEFVKKRDGRVIPFNEDRITRAIFLAATNVAEREGIVPDYKLS
                     EQLTQEVIKFLNHKYSESVPSVEDIQDSVVKVLIETGHAKTSEEYIIYRTERSRIRNS
                     KTRLMKAIEEITFEDAEDADIKRENANINGNTAMGTMLQYGSTVSKEFCKTHILKPEH
                     SFAHDNGDIHIHDMDFLNMGTLTCCQIDVKKLFNGGFSTGHGFLREPQDIISYGALAA
                     IAIQSNQNDQHGGQSIPFFDYGLAEGVYKTFKKFYIGNLAKALKLFKGIENNDVIKNI
                     VYNTEKETNQKVGLKRDELYLNLEKEKLIQTFDIDDELVNKMQNFAFEESYRETDKKT
                     YQSMEAFIHNLNTMHSRAGAQVPFSSVNFGTDTSEEGRMVTKNLLLSQERGLGNGETP
                     IFPILIFKVKEGINLNPEDPNYDLFKLSCRVSAKRLFPNFSFLDAPFNAKYYKKGEPD
                     TEATYMGCRTRVLSNVCGSETVSGRGNISFTTVNLPRLGIKHGIINNEKANLDGFFEE
                     LDEKINLIIEQLLERLEVQGNKKMKNFPFLMGQGVWKGSDDLGPEDTLKEVIKQGTLT
                     IGFIGLAECLIALIGKHHGESKEAQELGLKIVSHMRHKMDEATDKYKLNFSLMGTPAE
                     GLSGRFTKIDKKVYGEIKGITDKEYYTNSFHVPVYYNISAYDKIEIEAPYHELTNAGH
                     ITYVELDGDPSDNLEAFETVIKAMKDLGIGYGSINHPVDRDPICGFSGVITSNICPVC
                     GRNEDESDIKFERIRRITGYLVGTVDRFNNAKKAEVRDRVKHR"
     gene            4134..4673
                     /gene="nrdG"
                     /locus_tag="KRH23_003728"
     CDS             4134..4673
                     /gene="nrdG"
                     /locus_tag="KRH23_003728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043365 -
                     [formate-C-acetyltransferase]-activating enzyme activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HHS5226991.1"
                     /translation="MKIRMSSTISYDSIVDGPGLRMVIWTQGCIHNCKECHNPQTHDL
                     CGGFYMDTEEIINKVKSLKLQKGITLSGGEPFLQPEPLEEIAKEAKINGLDVWSYTGF
                     TFEQLLDKKNRAYFKNLNLLKQIDILVDGKFIAEKKDISLKFRGSSNQRIIDVQKSLK
                     YKQVFLVEQYMKDDLSIAE"
BASE COUNT         2092 a          594 c          851 g         1810 t
ORIGIN      
        1 ttataataaa tttagaattt aacttatata gtttaatttg ataatttgat gaaaaaaata
       61 aaagacttac tgatttttaa atctataggt cttttatttt ttatctaaca tttaaattaa
      121 gttgttgaat atatcttata ttacttacca tatatattaa ttaccattaa tacattatat
      181 ctaattacta ttcatctaaa ttattatgcc attattttat atacaaattc ttttaattta
      241 tctaatccag ataagaaagt attttcactg caagcatagg atatacgaat atatttatcc
      301 ataccaaatg ctatgccagg aacaactgca acattatatt cttctaaaaa ttgattacaa
      361 aattctatag aaaaactatc tttatattca aatttctcag atactttaga aagatctata
      421 aatatataga atgcgccatt tggattcaca tatcctacat tatcaataga gtctagtttt
      481 gatttaatta aatctcttct tgatttatat gttttaacca tattgtctat gtcaattgag
      541 caatctttca aggctccata ggctatgtat tgtgctgtta gacttgggtg agatataaga
      601 tgtccttgta tagaactcat tgctttagca atcgttttat tagatgcagt atatcctaat
      661 cttaatccag tcattgcagc tgacttagaa aaaccattta tagttattgt tatatcttta
      721 gcttcttcgc ttaatgatgc aattgatgta aattcaccag tgtagcatat tttttcatat
      781 atttcatctg ctaaaatata tattttattt tgtatgcata catctactat ttctattaat
      841 tcatcttttg tataaacact accagtagga tttgaaggat tgtttattac aagaattttt
      901 gttttatctg ttatagattt ttcaagttct tcttttgtta acttaaatcc attttctttt
      961 ttagtatcaa taaaaactgg aacagcatta actaacttaa tcatttcagg ataactaacc
     1021 caataaggct ttggtaataa gacttcatct ccttcgtctg ttaaagctag taaagtattt
     1081 gttattgagt tttttgctcc acttgataca actatttcgt ctattgaata gttacagtta
     1141 ttttcttcaa taagtttttt acagatttcc tctctaagta tttttaatcc tggaactaaa
     1201 tcatatttag tgtaatcttt atttaaagaa tcaataccat aagattttgc gttattaggt
     1261 acattaaaat cgggttctcc tatactaaga tttattactt taactccatt actttctatt
     1321 tctttaactt tagaactaat acctattgtg taggatggtg ttataaagtt tagtcttttt
     1381 gataacataa aatgcctcct tttaaattat tatttatatt atacgacaaa tttaaagaat
     1441 ttacataagg aaatttgtag atatatacat taatatatat aatagcctac actttttgcc
     1501 taaaattagt gtaaaaaaaa gagaaaaaaa ttttaacttt caaagttgtt agaaacgcta
     1561 ctgttcaaaa tatccacata gtatttgcaa tgatttgcgc aagtttgact attatgtaca
     1621 aatttggtaa tcttaatata gcaattatta agataatccc tttaacttag ttgaagggga
     1681 tttttttaga cttaacatac tacatatagt ggtatgggga ttaataaaat acaatatata
     1741 gtaacaggag gtttttttaa ttggttgaat tcgtaaaaaa aagagatgga agagtaattc
     1801 catttaatga agatagaata acaagagcta tatttttagc agcaacgaat gttgcagaaa
     1861 gagaaggaat agtacctgat tataaattat ctgagcaatt aactcaagaa gtaataaagt
     1921 ttttaaatca taaatactca gaatcagttc caagtgttga agatatacaa gattctgtag
     1981 ttaaggttct tatagaaact ggccatgcaa aaactagtga agaatatata atatacagaa
     2041 ctgaaagaag tagaataaga aattcaaaaa caagattgat gaaggcaata gaggaaatta
     2101 cctttgaaga tgcagaagat gctgatataa aaagagaaaa tgcaaatatt aatggtaata
     2161 cagcaatggg aactatgtta caatatggaa gcactgtatc taaagaattt tgtaaaacac
     2221 atatattaaa accagagcat tcttttgctc atgataatgg agatatacac atacatgata
     2281 tggatttttt aaatatggga acattaactt gttgtcaaat agatgttaaa aaactattca
     2341 atggtggatt ttcaacagga catggctttt taagagagcc acaagatata ataagttatg
     2401 gtgcattagc tgcaattgct atacaaagca atcaaaacga tcaacatgga ggtcaaagta
     2461 taccattttt cgattatgga ttggctgaag gtgtatataa gacatttaag aaattctaca
     2521 taggaaattt agctaaagca ttgaagttat ttaaaggaat tgaaaataat gatgtgataa
     2581 agaacatagt atataataca gagaaagaaa caaatcaaaa agttggtctt aagagagatg
     2641 aattgtatct aaacttagaa aaagagaaat taatacagac ttttgatata gatgatgaac
     2701 ttgtaaataa gatgcaaaac tttgcatttg aagaatcgta tagagaaact gataaaaaaa
     2761 catatcaatc tatggaagca tttatacaca atctaaacac aatgcactct agagcaggtg
     2821 cacaggtacc attttcaagt gtaaacttcg gaacagatac ttctgaagaa ggaagaatgg
     2881 taactaagaa tcttctatta tctcaagaaa gaggtttagg taatggagag acaccaattt
     2941 ttccaatttt aatatttaag gtcaaagaag gcataaattt aaatcctgaa gaccctaatt
     3001 atgatttatt taaattatca tgcagagtat cagctaaaag actattccct aattttagtt
     3061 ttttagatgc gccttttaat gcaaaatatt ataaaaaagg tgaaccagat acagaggcta
     3121 catatatggg ttgtagaaca agagtactta gtaatgtgtg tggttcagaa acagttagtg
     3181 gtagaggaaa catatctttt actacagtaa atttaccaag attgggtata aaacatggta
     3241 ttataaataa tgaaaaggct aatttagatg gtttctttga agaattagat gagaagataa
     3301 acttaattat agaacaatta ttggagcgcc ttgaggtaca aggaaataaa aagatgaaga
     3361 attttccatt cttaatgggg caaggtgtat ggaaaggttc tgatgattta ggaccagaag
     3421 atacactaaa agaagtaata aaacaaggaa cattgacaat tggatttata ggtttagcag
     3481 agtgccttat tgctcttata ggtaaacatc atggagaaag taaagaagct caagaattag
     3541 gattaaaaat agtgtcacat atgagacata aaatggatga agcaacggac aaatataaat
     3601 taaatttctc cttaatgggt actccagcag aaggtctttc aggtaggttt actaaaatag
     3661 ataaaaaagt ttatggagaa attaaaggta tcacagataa agaatattat actaattcat
     3721 tccatgtacc agtttattac aatataagtg catatgataa aattgagata gaagctccat
     3781 accatgaatt gactaatgca ggtcatataa catatgtaga gttagatgga gatccatctg
     3841 ataatttaga agcttttgaa actgttataa aagctatgaa agatttgggt ataggatatg
     3901 gaagtataaa tcatcctgta gatagagacc caatatgcgg tttttcaggt gtaataacaa
     3961 gtaatatatg ccctgtatgt ggaagaaatg aagatgaaag tgatatcaaa ttcgaaagaa
     4021 taagaagaat aacaggatat ttagttggta cagttgatag atttaataat gctaaaaaag
     4081 cagaagtaag agatagagta aaacatagat agttttattt gggggaataa gttatgaaaa
     4141 taagaatgtc atctactata agttatgaca gcatagttga tggaccagga ttaagaatgg
     4201 taatatggac tcaaggatgt attcataatt gtaaagagtg ccataatcct cagacacatg
     4261 atttatgtgg aggattttat atggatacag aagaaattat aaataaagtc aaatcattga
     4321 aattacaaaa aggcattacg ctatcaggag gagaaccatt tttacaacca gaaccattag
     4381 aagaaatagc aaaagaagct aaaataaatg ggttagatgt atggtcatat actggattta
     4441 cgtttgaaca actgttagat aaaaaaaata gagcgtattt taaaaattta aatttactaa
     4501 agcaaattga tattttagtg gatggaaaat ttatagctga aaaaaaagat ataagcttaa
     4561 agtttagagg gtcatcaaat caaaggataa ttgatgttca aaaaagtttg aaatataaac
     4621 aagtgttttt ggttgagcaa tatatgaagg atgatttatc tatagcagaa taaaatataa
     4681 ataaacagga ttaaatatat gcatatattt aatcctgttt attttcatat aatatttcaa
     4741 gcttgtataa tgtaacaatt aaaccaaaag actcattgta tatttgaaat taagtttttt
     4801 atagtttata ggtgttttat gtggattacg aatgatatag tattgataca ttatttaata
     4861 gattcttatg ccaagaaaca attaatttat agaaattttt aattgttaca atataaatat
     4921 ctagataagt tataagatac tgataaataa tttataaagt ttattaatct aatattgtgt
     4981 gtgaatatta agtggtcaag tagtctaaaa atgaaaaaga tttaaaaaag tgttttaact
     5041 aaacacataa gtgttaaatt catgtataag tataggttag atacataaga aataattatg
     5101 taatatctat ctttgtaaaa aaatattaaa ttttgtaatt tgtggataaa tatgtttata
     5161 atgtggataa tatttaatgt aataagttaa agcaatatga atcaactgtt tataatgtgg
     5221 ataatattat aaatgtatga ataattgcag tatttaaaaa caaaaaaagt taaaaaagtt
     5281 gttgactcta aaagaaaaag ttggtatagt aatacttgtc ctcaagaaaa gggcaaacaa
     5341 ataaagc
//
LOCUS       DAEORM030000118         5303 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.124, whole genome shotgun sequence.
ACCESSION   DAEORM030000118 DAEORM030000000
VERSION     DAEORM030000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5303)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5303)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 5303)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5303
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.124"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            <1..518
                     /locus_tag="KRH23_003729"
     CDS             <1..518
                     /locus_tag="KRH23_003729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HHS5226992.1"
                     /translation="KNLEQLNNPTHSTNRIYDAVGIARCIRSQAGGGGAKTGLYFIDL
                     NKNSKVTINARCLKAKYNAGVTNRNCDNSGVLVNAVLTPDRVNKRQNGRRIKESGETM
                     FTLTAQDKHGILKNGDIRRLTPKECFRLQGFPDKYYERAASVCSDSQLYKQAGNAVTA
                     NVVYEIAKRMG"
     gene            598..807
                     /locus_tag="KRH23_003730"
     CDS             598..807
                     /locus_tag="KRH23_003730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226993.1"
                     /translation="MYEYILRWQIGLSLENRKIHYTYGSKEALRKKAKALAKDENIVL
                     ITIDKVDEVIKNTISEKIIERFENL"
     gene            819..1823
                     /locus_tag="KRH23_003731"
     CDS             819..1823
                     /locus_tag="KRH23_003731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HHS5226994.1"
                     /translation="MIIHKFIIHVLDKNSDTPILNDFEGRVNQDMVLFFQKKISKVSR
                     DNDIRTAVFNNYSNNLIKKCCEQIIYDESSFLNNSKEIAAYLFDVMKLNATLESCDLA
                     ICLYSQKDEKKVAILKLDYNNSYTHSIEFKDDKFNIQMSKNEINIQETKTVKIAALVG
                     LSGMNDKYHLRVLDKDAEKEEANSKFVTEFLNATKIKDDKYKTKKFKNTAENWITNAL
                     SNDIKQAEDVRSILNYTLREKHEIDINDFVDKTIKDDKLKDSFKEHMEEKGLVEGFSI
                     DKKWVDKKLKKRNIKTDNGFEIKGNLTDFEDPMKYTVRQNQNGSIDIVIKNVTFYEEK
                     "
     gene            1905..2234
                     /locus_tag="KRH23_003732"
     CDS             1905..2234
                     /locus_tag="KRH23_003732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226995.1"
                     /translation="MKIFLLTILLIIICILANYVKNRIYKKSINNLKYKYSVGEKIIY
                     HQINCYYNRMVGCEILEKCYSTKFRKRNTPLYKVKAYVGDNDTTWVIPEWRIECLATT
                     YGEFPKY"
     gene            2271..2642
                     /locus_tag="KRH23_003733"
     CDS             2271..2642
                     /locus_tag="KRH23_003733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226996.1"
                     /translation="MFNIYKVKIKTKRTLEQVRNQSVDFEYSEKGLKNTLKYYNLIDD
                     LKVIVVKFGDEYCLANYNEEDRKIIMEAHYLLEQDEYTGCYINEYERFKKDWENGNCD
                     GEACMVFSDDEIEIIEKLREG"
     gene            2645..2827
                     /locus_tag="KRH23_003734"
     CDS             2645..2827
                     /locus_tag="KRH23_003734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5226997.1"
                     /translation="MNKRIKMKKRLIHKKCDERCVNYDFVISNNLITCNVCIGCKYKE
                     NMDKVCEENYKKLRSK"
     gene            2907..3248
                     /locus_tag="KRH23_003735"
     CDS             2907..3248
                     /locus_tag="KRH23_003735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003747 - translation release factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor family protein"
                     /protein_id="HHS5226998.1"
                     /translation="MANIYCENYNCKNYFEDMCMLERIEINNFKECESYLEGKNELYE
                     LENGYTIHPKDLKMVKSKDYSVEVTHIPTGITVKCRSTNSILKNKNKCLEVLEEELTK
                     INSHLELEDLR"
     gene            3374..3781
                     /locus_tag="KRH23_003736"
     CDS             3374..3781
                     /locus_tag="KRH23_003736"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0000400 - four-way junction DNA binding
                     [Evidence IEA];
                     GO_function: GO:0008821 - crossover junction DNA
                     endonuclease activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HHS5226999.1"
                     /translation="MKVFLVIDGEPVGKERPRMNTYAKRTYTPNKTKNYEDLIKWLYQ
                     SKVKYYFEGYIKMTLRCYYSIAKSNSKKVKEQKRNNVLRPSKKPDIDNVIKVVADSLN
                     EIAYKDDTQIVEVVASKYYSDNPRVEVILEDVI"
     gene            3883..4731
                     /locus_tag="KRH23_003737"
     CDS             3883..4731
                     /locus_tag="KRH23_003737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ORF6C domain-containing protein"
                     /protein_id="HHS5227000.1"
                     /translation="MNENINKEITVLGTLEIEGMKFHNIEGGFGEHKKAMLVKDIAEI
                     HNRESRQINELINKNRKRFKDGKDILDLLGVGLDDTKIKELGFTQQSINSYRGLKNKG
                     LLSGIYILSERGYAKLLKILEDDIAWELYEKLVDGYFSMRKELNNPLLSASKELQAIF
                     MLDKKQEVLETKIENVNEKLENFMDDAPLFNIECESIVKEVKKVATKSLGGHGSKAYK
                     NKSLRGKVYNDIYHQIKREFGVDSYKAIKRCQLNKVLEIVNNYKLPIVFEEEIRLLNS
                     QLSIVS"
     gene            4834..>5303
                     /locus_tag="KRH23_003738"
     CDS             4834..>5303
                     /locus_tag="KRH23_003738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5227001.1"
                     /translation="MDNNINKKELFKKVEGRLHHYKFLSAEIKNLELDIESRENEIFG
                     CKAVGYDEKVSPTYAFNSTVENEIIKKERDITRLKKLKKDKEIEKKKIENALTCLDIR
                     EEHFFKLFYNSRMKNSMVYISLEMNSDRKTCRCVRERLVYKVMDMLYPRIKENEL"
BASE COUNT         2279 a          465 c         1013 g         1546 t
ORIGIN      
        1 gaaaaaatct tgagcaacta aataatccaa ctcatagtac aaatagaatt tatgatgcag
       61 ttggaattgc tagatgtatt agaagtcagg caggaggtgg aggtgctaaa acaggtctat
      121 actttataga cttaaataaa aactctaaag taacaataaa tgctagatgc cttaaagcaa
      181 aatataatgc aggtgtgaca aatagaaatt gtgataatag tggagtttta gttaatgcag
      241 ttttaacgcc cgatagggta aataaaagac aaaatggtcg tagaattaaa gaaagcggag
      301 aaacaatgtt cacactaaca gctcaagata aacatggaat tttgaaaaat ggagatataa
      361 gaaggttaac accaaaggaa tgctttaggt tgcaaggatt tccggataaa tattacgaaa
      421 gagcagcaag tgtatgctca gatagtcaac tgtacaagca agcaggaaat gctgttactg
      481 caaatgttgt atatgaaata gcaaaaagaa tgggctaaaa gttgcaaaat gtcttttagt
      541 atgaatattt ttgaagtgtt ttgtaactct caaaaatgaa aataaggggt gggataaatg
      601 tatgaatata tattaagatg gcaaatagga ttatcgttag aaaatagaaa aatacattat
      661 acatatggaa gtaaagaagc tttaagaaag aaagcaaagg cattggctaa agatgaaaat
      721 atagtactaa taactataga taaggtagat gaagttataa aaaatactat aagcgagaag
      781 attatagaac gttttgaaaa tttataaggg gtggaattat gataatacac aaatttataa
      841 tacatgtttt agataagaat agtgatacac caatattgaa tgattttgaa ggtagggtta
      901 atcaagatat ggtcctattt tttcaaaaga aaataagcaa agtatcaaga gataatgaca
      961 tcagaacagc agtatttaat aactatagta acaatctaat taagaagtgt tgtgaacaaa
     1021 ttatttatga tgaaagttca tttttaaata actctaaaga gattgcagct tatttatttg
     1081 atgttatgaa attgaatgct acattagaat cttgcgactt agcaatttgt ttatactctc
     1141 aaaaagatga aaagaaagtt gctatattaa agcttgatta caataattcg tatactcatt
     1201 caattgagtt taaagatgat aaatttaata tacagatgtc taaaaatgaa attaatatac
     1261 aagagactaa gacggttaaa attgctgctt tggttggatt gagtggaatg aatgacaaat
     1321 atcatcttag ggttttagac aaggatgcag agaaggaaga agctaattct aagtttgtta
     1381 cagagttctt aaatgccact aagataaaag atgataagta taagactaag aagttcaaaa
     1441 atacagctga gaattggata actaatgctc ttagtaatga tataaaacaa gcagaggatg
     1501 taagaagtat attaaattat actttgagag aaaagcatga aattgatata aatgattttg
     1561 ttgataaaac aattaaagat gataagttaa aagatagttt taaagaacat atggaagaaa
     1621 aaggtcttgt tgaaggattt agtatagata aaaaatgggt tgataaaaag cttaaaaaga
     1681 gaaatataaa aactgacaat ggctttgaaa taaaaggtaa cttaactgat tttgaggacc
     1741 caatgaaata tacagtaaga caaaatcaaa atgggtctat agatatagtt attaagaatg
     1801 taacatttta tgaggaaaag taggtactca tgtgactatt ggctagagaa ggagaagtaa
     1861 ataataagag gatgtaaatt taaactagtt aggaggaata acttatgaag atttttttat
     1921 tgactatact gctaataatt atttgtatat tagcaaatta tgtgaaaaat cgcatatata
     1981 aaaaatctat aaataatcta aaatataaat attctgtagg ggaaaagatt atatatcatc
     2041 aaataaactg ttactataac agaatggttg gttgtgaaat tttagaaaaa tgttatagta
     2101 cgaaatttag aaaaagaaat accccgcttt ataaagtaaa agcatatgta ggtgataacg
     2161 atacaacatg ggttatacca gagtggagaa ttgaatgtct tgctacgact tatggagaat
     2221 ttcctaaata ttaaataata aaaattggct ggagaaggag attgtaaatt atgtttaaca
     2281 tctataaagt gaaaataaag actaaaagaa cattggagca ggtaagaaat caaagcgtag
     2341 actttgagta ttcagaaaaa ggattaaaaa atactctgaa atactataac ttgattgatg
     2401 atttaaaagt aatagtagtt aaatttggag atgaatattg tctagctaat tacaatgaag
     2461 aagatagaaa aataataatg gaagcacatt atcttttaga gcaggatgaa tatactggat
     2521 gttatataaa tgaatatgaa cgatttaaaa aagattggga aaatggtaat tgtgatgggg
     2581 aagcctgtat ggtattttca gatgatgaaa ttgagataat tgagaagcta agggagggtt
     2641 aaatatgaat aaaagaatta aaatgaaaaa aagattaatt cataaaaagt gtgatgaaag
     2701 atgtgtcaac tatgactttg taattagcaa taaccttata acttgtaatg tgtgtatagg
     2761 atgcaaatac aaagaaaata tggataaagt atgtgaagag aactataaga aattaagaag
     2821 taaatagaat aaaatagtca aggtaagttt gtgaatgaaa ctagaatgtt atagacttac
     2881 tttgacttat aaaaggagtg tgttaaatgg ctaatatata ttgtgaaaat tataattgta
     2941 aaaactactt tgaagatatg tgtatgcttg aaagaattga aattaataac ttcaaagaat
     3001 gcgaaagcta tcttgaaggt aaaaatgagc tatatgaatt agaaaatgga tatactatac
     3061 atcctaaaga tttgaaaatg gtgaaaagta aagattattc tgttgaagtt actcatattc
     3121 caactggtat tacagtaaaa tgccgttcta caaatagtat tttaaaaaat aaaaataagt
     3181 gtttggaagt tctagaagaa gaactaacaa aaataaactc tcacttagag ctagaagatt
     3241 tacgctaaat aggaagtgag cttatgaaac gaagaagatg cagttggtgt ggtaagttat
     3301 tttatcttga agaaaaatct aaggatgttt attgttgtaa agaatgtagg aagaaggcta
     3361 agaaggtgaa aaaatgaaag tttttcttgt aatagatgga gagccagttg gcaaggaaag
     3421 accaagaatg aatacttacg ctaaaaggac ctatacacct aataagacta agaattatga
     3481 ggacctaata aaatggctat atcaatctaa agttaaatat tactttgaag gttatataaa
     3541 aatgacttta agatgttatt attctatagc taaaagtaac agtaaaaagg ttaaggagca
     3601 gaaaagaaat aatgtgttaa gacctagtaa aaagcctgac attgataatg tcattaaagt
     3661 agtagctgat tcactcaatg agatagctta taaggatgat acacagattg ttgaggttgt
     3721 agctagtaaa tattatagcg ataatcccag ggttgaggtt atattagaag atgttatcta
     3781 accaacggaa aaatccgttc gttaaattat gcccttagtt tttcataaaa atgtgaaaaa
     3841 gctaaataaa gaatatatca aacgacaaag gagagataaa ttatgaatga aaatataaat
     3901 aaagaaataa cagtacttgg aactttagaa atcgagggaa tgaaatttca taacattgag
     3961 ggtggatttg gagaacataa gaaagcaatg ctagtaaaag atatagccga gatacataat
     4021 agagaatcta gacagattaa tgagcttata aataagaata gaaaaagatt taaagatgga
     4081 aaagatatat tagatttgtt aggtgtcggt ttggacgata ccaaaataaa agaattagga
     4141 tttactcaac aatcaattaa ttcttataga gggttaaaaa acaaagggtt attatctggg
     4201 atttatatat tatctgaaag aggttatgca aaattattaa aaatattaga agatgatata
     4261 gcttgggaat tatatgagaa gttagttgat ggatatttct ctatgagaaa agaactaaat
     4321 aatcctcttt taagtgcatc aaaggagtta caggctatat ttatgctaga taagaaacaa
     4381 gaagtcttag aaactaaaat agagaatgtt aatgagaaat tagagaactt tatggatgat
     4441 gcaccactat tcaatattga atgtgaaagt attgtaaaag aagttaagaa ggtagcaaca
     4501 aaatcactag gaggtcatgg aagtaaggct tataaaaata aatctttaag aggtaaagta
     4561 tacaatgata tataccatca gattaaacga gagtttggag tagatagtta taaggctata
     4621 aagcgttgtc aattaaataa agtattagag attgtaaaca attataagtt acctatagtg
     4681 tttgaagaag aaataagact tttaaatagt caattatcaa tagtaagtta aatttattca
     4741 aaaaaaagga aaaggagtgc tttcacactc cacttgtcaa aaatataaaa cttttatcca
     4801 agattattat aacataaaca ggagtgtgga agtatggata ataatatcaa taaaaaagaa
     4861 ctatttaaaa aagtagaagg tagattacat cattataaat ttttaagtgc agaaattaag
     4921 aatcttgaat tagatataga aagtagagaa aatgagatat ttgggtgtaa ggctgttgga
     4981 tatgatgaaa aagtaagtcc aacatatgct tttaattcaa ctgttgagaa tgagattata
     5041 aaaaaagaaa gagatattac tagattgaaa aaactgaaaa aagataaaga aatagaaaag
     5101 aagaaaatag aaaatgcact tacatgctta gatataagag aagaacattt ttttaaactg
     5161 ttttataata gtagaatgaa aaatagtatg gtttatatat ccttagagat gaactcagat
     5221 aggaaaacat gtagatgtgt aagggaaaga ttagtgtata aagttatgga tatgctttat
     5281 ccaagaatta aggaaaatga act
//
LOCUS       DAEORM030000119         5255 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.125, whole genome shotgun sequence.
ACCESSION   DAEORM030000119 DAEORM030000000
VERSION     DAEORM030000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5255)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5255)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 5255)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5255
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.125"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            60..1064
                     /locus_tag="KRH23_003739"
     CDS             60..1064
                     /locus_tag="KRH23_003739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HHS5227002.1"
                     /translation="MRFKRILILMLTVAMIAGMLVGCANNPSNNPSSSKDNKSDISDK
                     SNSKKSVSMILDIEGTNNEAMNNSALLALNNAQKKLNIDTNKVESDDSSTFSNSIDIL
                     CNDNYDLIIAVGARFAKPLEMVAKKYPKQQFAIIDYEYDKQPSNITSISYEDNKSGYL
                     AGLIAGKMTESDKVGFIGGVKSSSRDKFESGFREGVKFSNSSIKDISVEYADVFKDSK
                     SVESIAKKMMDNGVDIIFSTTEDDSKAVIDAVRAKNKKVIATNKDQHELAPENVISSI
                     VKDFENPTYNLIQSFVKGNYKGGKVIENTVKSGSTGLAQNSSQNIPPDVLEYVNKNNK
                     "
     gene            1190..2302
                     /locus_tag="KRH23_003740"
     CDS             1190..2302
                     /locus_tag="KRH23_003740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HHS5227003.1"
                     /translation="MKIKRILMACFVVVFTIFILAICNFDFGFDKVNKNNSNIDSAKS
                     KQSESKSLPTSAEKDKSNSKSKNKEDDTEDDSYVRKTIGVLLDTENLNNESYNNNVLS
                     ALKRADEDFDVRIKLEKPKTSKSFKESIEKLHKYEPDLIIAVGARFAEPIKEAATKYP
                     KQQFAIVDYTYKVQPANVISVSFQDNVTGYLAGLIAGKMTDTGKVGFIGGVEGSSRDK
                     YESGFRKGLKTSNKDAELLVKYSNIFENPESARTIAKEMRDSDRDVVFSATEDDSKRA
                     IQVARENGGKVIAINKDQYDMAPDNVISSIIKDVEQPVYELIKNVAKDGFKGSKVMEF
                     KIKDGELGLTSKSSRNIPPDVLEYIKKEYNKVKDTY"
     gene            2792..3553
                     /locus_tag="KRH23_003741"
     CDS             2792..3553
                     /locus_tag="KRH23_003741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6873 family GME fold protein"
                     /protein_id="HHS5227004.1"
                     /translation="MEFTREPFILDDDLCLALVDKRISYLMENELKLRNIEIIKTIEC
                     KELYESIKYHPDICICNLGKGDIIVAPNVYNQYKELLSRYKFNIIKGEANLLNRYPYD
                     IPYNIAIVGDYAIHNFKYTDKAILDYIENNKLKKINIEQGYSKCSICIVDRTSIITSD
                     KGIWKSMKNTEIECLLIEKGHINLFEMNYGFIGGCTGLISKDKLAFCGDVKKHPDYER
                     IKSFVESKNKEIVTLSCENLLDIGSIVPLMTRKER"
     gene            3556..4374
                     /locus_tag="KRH23_003742"
     CDS             3556..4374
                     /locus_tag="KRH23_003742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative sporulation protein YtxC"
                     /protein_id="HHS5227005.1"
                     /translation="MVEKDNISSMKFLRNNNVNDRLIYTNDIVEVVIDSAKQEVLNKK
                     ILNGTKAEQRALNIDEISTEITSMIISIMKEKLLKEYILKCYGRTYPEDKNNIYIYSL
                     NIFAKKEIFMRETVFTRVRNYIEENDFINVEGFIRFRMREFMKYISAIGDIAVEEYLI
                     KKDQDEFIRVLKYFIDTQEEKIDLLKVHIMEDNTFVLYDKNGNKIDSIDDEEIINMVI
                     RENLNYEDFLISTLLTLCPKKIEILDLLNNNCSKEIIDTVEAIFENKVSIIMEN"
     gene            4554..5156
                     /locus_tag="KRH23_003743"
     CDS             4554..5156
                     /locus_tag="KRH23_003743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF445 domain-containing protein"
                     /protein_id="HHS5227006.1"
                     /translation="MDNLIRILILAVIGGFIGYVTNVVAIRLIFRPIEPIKIPILNIE
                     IVGLIPKRRAEIAANVGEIIQEEFLSMDEILANIITDEDKEEVVRYIKARVKIIIHEK
                     VSFIPSGIKNMIQDYLGEIIESEVKQSIDELSKNIINKANERIDIQKMVEDKINELDL
                     YELEEIIIRIAKKELKHIEFLGLVLGFLIGIAQGLITMFI"
BASE COUNT         2193 a          486 c          941 g         1635 t
ORIGIN      
        1 taggatgtaa aaataaatag gatataaaaa tatcgtaaat gtatgaggag tgaaatttaa
       61 tgcgtttcaa aagaatattg atattgatgt taactgtagc aatgatagct ggaatgttgg
      121 ttgggtgtgc taataaccca agcaataatc ctagctctag caaagataat aaaagtgata
      181 taagcgataa aagtaattca aaaaaatctg tatcaatgat actagatatt gaaggaacaa
      241 ataatgaagc tatgaataat tcagctttat tagcattaaa caatgctcaa aagaaactta
      301 atatagatac aaacaaagtg gaatcagatg attcctcaac tttttctaat agtatagata
      361 ttttatgtaa tgacaattac gatttaatta tagctgtagg agctagattt gcaaaaccat
      421 tggagatggt agccaagaaa tatccaaagc aacaatttgc aattatagac tatgagtatg
      481 acaagcaacc ttctaatata acttcaattt cttatgaaga taataaatct ggatacctag
      541 ctggattaat tgctggaaaa atgactgaaa gcgataaggt tggctttata ggaggagtaa
      601 agagctctag tagggataaa tttgaatcag gttttagaga gggtgttaaa ttttctaata
      661 gtagtataaa ggatatttca gttgagtatg cagatgtttt taaagatagc aaatcagtag
      721 aatctatagc taaaaaaatg atggataatg gagtggatat tattttttct actactgaag
      781 atgattcaaa agctgtaata gatgcagtaa gggcaaaaaa taaaaaagtt atagcaacga
      841 ataaagacca acatgagtta gctccagaaa atgttataag ttctattgta aaagattttg
      901 agaatcctac ttataatctg atacaaagtt ttgtaaaagg aaattataaa ggcggaaagg
      961 ttatagaaaa cacagttaag tctggaagta ctgggcttgc ccaaaatagt tctcaaaata
     1021 ttcctccaga tgtgttagaa tatgttaata agaacaataa ataatctact ataatatcca
     1081 agaatactta tgactttagt tatgaggtga attggatgtt ataatagaca tatatagaaa
     1141 gacatatgca gaggtaggtc agacctatct aaatcaggga gtgaattttg tgaaaataaa
     1201 aaggatattg atggcttgct ttgtagtagt ttttacaatt tttatattag ctatatgtaa
     1261 ttttgatttt gggtttgata aagtaaataa gaataattct aatatagata gtgctaaatc
     1321 gaaacagagt gagtctaaaa gtttgccaac ttcagcagaa aaggataaat caaatagtaa
     1381 aagtaagaat aaagaagatg acacagaaga tgattcatat gtaagaaaaa ctattggagt
     1441 attgttagat accgaaaact taaataacga atcatataat aacaatgtac tatcagcctt
     1501 aaaaagggct gatgaagatt ttgatgttag gataaaactt gaaaaaccaa agacttctaa
     1561 aagttttaaa gagagtatag aaaaactgca taagtatgaa ccagatttga taatagcagt
     1621 tggagccaga tttgcagagc caattaaaga agctgctact aaatatccca aacagcaatt
     1681 tgcaatagtt gactatactt ataaagttca gccagctaat gtaatttctg tatcatttca
     1741 agataatgtt actggatatt tagcaggact tattgcaggt aaaatgactg atactgggaa
     1801 agtcggtttt ataggaggag ttgagggctc tagtagagat aagtatgaat ctggatttag
     1861 aaaggggctt aaaacttcaa ataaagatgc tgagttacta gttaagtatt caaatatatt
     1921 tgaaaaccct gaatcagcta gaactattgc aaaggaaatg agagattctg atagagatgt
     1981 tgtattttca gctacagaag atgatagtaa aagagctatt caggtagcaa gagaaaatgg
     2041 tggtaaagtt atagctatta ataaagacca atacgatatg gctccagata atgtaataag
     2101 ttcaattata aaagatgtag aacaacctgt atatgaactg ataaagaacg ttgcaaaaga
     2161 tggttttaag ggaagtaaag taatggaatt taaaataaaa gatggggaac ttggcttgac
     2221 ttcaaagagc agtagaaata taccaccaga tgttttggaa tacataaaaa aagagtataa
     2281 taaagtgaaa gatacatatt aattattgat gtagaagatt ataaaaatat attgattaag
     2341 tttagattag caataaaaag atatatttat taaatttgtg ctaactgtac aaaatatatt
     2401 gattaagttt agattagtga taaaaagata tatttattaa atttgtgtta acagtatgga
     2461 atatactgct taagtttaga ttggtgataa aaggatatat ttattaaatt tagtctaact
     2521 gtacaaaata tattgattga gtttagatta gcaataaaaa gatatattta ttaaatttgt
     2581 gctaactgta cggaatatac tgcttaagtt tagattagtg ataaaaagat atatttatta
     2641 aatttgaacc aactgtacaa agctatacta attaagctta gattaactat gtaaaattat
     2701 aacaataagt gtgtgggcag aaaaattctg ctacacactt tatttatatt cacataaaaa
     2761 atttatcaaa aaaaagaaaa aggagtaaaa aatggaattt acaagagaac catttatact
     2821 agatgacgat ttgtgtctag ctttggtgga caaaagaatt agttatctaa tggaaaatga
     2881 attaaaatta agaaatatag agataataaa aacaatagaa tgtaaagaat tatatgaaag
     2941 cataaaatat cacccggata tatgtatttg taatttagga aaaggagata taattgttgc
     3001 gccgaatgta tataatcaat acaaagagtt attaagtaga tataaattta atataattaa
     3061 gggagaagct aatttattaa atagataccc ttatgatata ccttacaata ttgcgatagt
     3121 tggtgactat gctatacaca attttaagta tactgacaaa gcaatattag attatattga
     3181 aaataataaa cttaaaaaga taaatataga gcagggctat tctaaatgct caatctgtat
     3241 agtagataga acgtctataa taacatcaga taaaggtatt tggaaaagta tgaagaatac
     3301 agaaatagag tgtttattga tagaaaaagg tcacataaat ttatttgaga tgaattatgg
     3361 atttataggt ggatgtacag ggttgatttc taaggataaa ctagcttttt gtggagatgt
     3421 taaaaaacat cctgactatg aacgtataaa aagttttgta gaaagtaaaa acaaggagat
     3481 agttacactt agctgtgaaa atttactaga tataggttct atagttcctc tcatgacaag
     3541 aaaggagcga taactttggt tgagaaggat aatatttctt ccatgaaatt tttgaggaat
     3601 aataatgtaa acgatagatt aatatatacg aatgacattg tagaagtagt gatagattct
     3661 gcaaagcaag aagtgttaaa taaaaaaata cttaatggta ctaaagctga acaaagagct
     3721 ttaaatattg atgagatatc aacggaaata actagtatga taataagtat aatgaaagag
     3781 aaacttttga aagaatacat tctaaaatgc tatgggcgta catatcctga agataaaaat
     3841 aatatataca tatattcact gaacatattt gctaaaaaag agatttttat gagagaaaca
     3901 gtatttacta gggtgagaaa ttatatagaa gaaaatgatt ttataaatgt agaaggtttt
     3961 attagattta gaatgagaga atttatgaaa tatatttctg ctataggtga tattgcagtt
     4021 gaggagtatt taataaagaa agaccaagat gaatttataa gagttttaaa atactttata
     4081 gatactcaag aagaaaagat tgatttgctt aaagttcata taatggaaga taatacattt
     4141 gttttatacg ataaaaatgg aaataagata gacagtatag atgatgaaga aattataaat
     4201 atggtaataa gagaaaattt aaattatgag gactttttaa taagtacctt attaactcta
     4261 tgtcccaaaa aaatagaaat attggatttg ttaaataata attgctcaaa ggaaattata
     4321 gatactgtag aagcaatttt tgaaaataaa gttagtataa ttatggaaaa ctagaatcta
     4381 agcatataaa agctatccat ataaaattaa aaaaattctt tttaaatcga cacaaaagac
     4441 ttataattgt atataaagct atagtataac tagagttatt aagtataaag aatatctact
     4501 tgattaatgc aatatagctg gcaaatatac aattgataag gagtaatttt ataatggata
     4561 atttaattag gatactgata ttagctgtta ttggtggatt tataggttat gttacgaatg
     4621 tagttgctat aagactgata tttagaccaa tagagcctat taaaatacct attttaaata
     4681 tagaaatagt aggtcttata ccaaagagaa gagcagaaat agcagcaaat gtaggagaaa
     4741 taattcaaga agaatttctt tctatggacg aaatacttgc aaatatcatt actgacgaag
     4801 ataaggaaga agttgtaaga tacataaaag caagggtaaa aattataata catgagaaag
     4861 tttcatttat cccgagtggt ataaaaaata tgatacaaga ttatctagga gagataattg
     4921 agtctgaagt taagcaaagt atagatgaat tgagtaaaaa tataataaat aaagcaaatg
     4981 aacgtataga tatacaaaaa atggtcgaag ataagattaa tgaactagat ttatatgaat
     5041 tggaagagat aataataaga atagctaaga aagaattaaa acatatagag tttttggggc
     5101 ttgtcttagg gtttttaata ggtatagctc aagggttaat tactatgttt atttaaatat
     5161 atgagaagta gcatttattt aagtactaat tatatttacc tatttgagtg aattacttat
     5221 taataacatt tagatattaa ttgtatttac ctatt
//
LOCUS       DAEORM030000120         4893 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.126, whole genome shotgun sequence.
ACCESSION   DAEORM030000120 DAEORM030000000
VERSION     DAEORM030000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4893)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4893)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 4893)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4893
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.126"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            complement(269..2404)
                     /gene="rnr"
                     /locus_tag="KRH23_003744"
     CDS             complement(269..2404)
                     /gene="rnr"
                     /locus_tag="KRH23_003744"
                     /EC_number="3.1.13.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HHS5227007.1"
                     /translation="MIPGLKESLLGLINESAYNPLKKEELAEIFDIHSSEMPMFYNFL
                     NELEEDGYICFTKKGKIVSPNQMGYFVGKFVSHKKGFGFVESDVEYTQDLFISSDNIN
                     GAMHNDRVMAEIVVPATEEKRAEGRIVKVIKREITRIVGTFQSSKTFGFVTPDNKKFT
                     KDIYIPKKHFSGAVDNDKVVCEITVWPQEDRKPEGKIIEILGQKGERGVEIDSIIREH
                     GLPEEFPKKVLQEAEAVAVEIPQEEIKRRRDLRDLNIFTIDGDDAKDLDDAISIEVLP
                     NGNFKLGVHIADVTHYVREKNKLDKEALKRATSVYLVDKVIPMLPKTLSNGVCSLNPF
                     EDKLTLSIFMEIDHKGNVVKHEICESVINSKARMTYTEVSDILEKDDEKLKKTFEHVV
                     EDFKNAEILARILMSRREKRGAIDFNFPEAKIILNGKGEVVDIKPYERRISNKIIEEF
                     MLISNETIAEHFYWMGIPFVYRIHETPSLEKMEELSKFISTFGYIIKGDKEEVHPKAL
                     QGIIEKIKGKKEEGAISTIMLRSLKQAKYSPECSGHFGLAAKFYCHFTSPIRRYPDLQ
                     IHRIIKESLNNKISGKRQEQLTTIVDYASVQSSEKERKAELAERDVHDFYKALYMKDK
                     VGQEFEGVVSSVTSFGIFVELDNTIEGLIRLANMNDDYYIYDESSYSVLGERTKKSYK
                     IGDLVKIKVESVNVDFKEIDFEIVEKIEE"
     gene            2999..3613
                     /locus_tag="KRH23_003745"
     CDS             2999..3613
                     /locus_tag="KRH23_003745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HEAT repeat domain-containing protein"
                     /protein_id="HHS5227008.1"
                     /translation="MEEVIAKIITIENGFKEIENIAKKIVKNNDSKKCYYLSIYLYRS
                     EYYQVRELAVFILGFISVTISEALLFLKDNVSKDENWRVQEILAKSFDYYCSEVGYEK
                     ALPVIKEWLNSDSPNIKRAVTEGLRIWTSRDYFKSNPDVAISLLSSLKEDDSEYLRKS
                     VGNALRDISKKYPDLVKKELDSWDISNKKVEFVYKLASKCILAK"
     gene            3631..3993
                     /locus_tag="KRH23_003746"
     CDS             3631..3993
                     /locus_tag="KRH23_003746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HHS5227009.1"
                     /translation="MKLRDEYTCPLELTHDMIKGKWKSIILWRLRIGPTSLSKLEKEI
                     NGINQKMLLEQLKELIEFGLVDKKTYEGYPLKVEYSLTPIRGKQILDALAIMQDIGIS
                     FMLDNGMQDILKEKGVLK"
     gene            4099..4596
                     /locus_tag="KRH23_003747"
     CDS             4099..4596
                     /locus_tag="KRH23_003747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbhB/YbcL family Raf kinase inhibitor-like
                     protein"
                     /protein_id="HHS5227010.1"
                     /translation="MKVTSTGIVNGVIEDKYGKRGTQFNEGGMPTYSLPLKFEDAPKN
                     TVSFAVFLEDKDSVPVCGFAWIHWLAVNITKDELNENESVTATDFVQGTTSWHGKLGG
                     LDRLEASVYGGMAPPDRPHVYEIHVFALDTILDLEKGFYMNEFFKAIEGHVLDTFTLK
                     GSYSN"
BASE COUNT         1612 a          741 c          604 g         1936 t
ORIGIN      
        1 ttatttttca gttggctttt tctattaaat gtttcttaat tacttatctt tcagttagct
       61 ctttctatta aacatttctc aattacttat ttttcaatta gctactttca ttaaatattt
      121 cttaattatt tatctttcag ttaactattt ccattagata tttctcaatt acctattttt
      181 atcatttatt ttatagagta ttgtgcacta tatatttata catatcataa atactacaac
      241 ttgttatctc ttattttagc tgttttatct actcctctat tttttcaact atctcaaagt
      301 caatttcttt aaaatctaca ttaacacttt caacctttat cttaacaagg tctcctatct
      361 tatatgactt cttagttctt tctcctaaaa cactataaga actctcatca taaatatagt
      421 aatcatcatt catatttgca agtcttatca acccttctat agtattatct aactcaacaa
      481 atattccaaa tgaagttacg ctagatacaa caccctcaaa ttcttgacca actttatcct
      541 tcatataaag agccttatag aaatcatgta catctctttc agctaactct gcctttcttt
      601 ctttctcgga tgattgaaca gatgcataat ccactatagt agtaagctgt tcttgtcttt
      661 ttccacttat tttattattt aaagattctt ttattattct atgaatttga aggtcaggat
      721 atcttcttat tggtgaagta aagtgacagt agaatttagc tgctaatcca aaatgtccac
      781 tacattctgg tgagtactta gcttgtttta aagaacgaag cattatagta ctgatagctc
      841 cttcttcttt tttgcccttt attttctcta ttataccttg taatgctttt ggatgtactt
      901 cctctttatc accttttatt atatatccaa atgtagatat aaacttactc aattcttcca
      961 ttttttccaa agatggtgtc tcatgtattc tatacacaaa cggtattccc atccagtaaa
     1021 aatgttcggc aattgtctca ttacttataa gcataaattc ttctattatc ttattagata
     1081 ttcttctttc atatggcttt atatctacaa cttcgccttt tccatttaga attatctttg
     1141 cctctgggaa attgaagtct atagctcctc ttttttccct tcttgacata agaatcctag
     1201 ctaaaatttc agcattctta aaatcttcaa caacatgttc aaaagtcttt ttaagttttt
     1261 catcatcctt ttctaatata tcagatactt ctgtataagt cattctagct tttgaattta
     1321 ttacagattc acatatttca tgtttaacca catttccttt atggtctatt tccataaata
     1381 tagaaagagt taacttatct tcaaatggat ttaagctaca tactccattt gaaagagttt
     1441 ttggcaacat tggaattact ttatctacta aataaactga tgtagctctt tttaaggctt
     1501 ccttgtcaag tttatttttc tctcttacat aatgtgtaac atcagctatg tgaactccta
     1561 gtttgaagtt tccattaggt aatacttcta ttgatatggc atcatctaag tcttttgcgt
     1621 catctccatc tatagtaaat atgtttaaat ctcttaaatc tcttcttctt tttatctctt
     1681 cttgaggaat ctcaacagct acagcttctg cttcttgcaa tactttcttt ggaaattctt
     1741 ctggaagacc atgttctctt attatagaat ctatttctac gcctctttca cctttttgac
     1801 ctagtatctc tataattttg ccttctggtt ttctatcctc ttgtggccat actgtaattt
     1861 cacatactac cttatcatta tctactgctc cactaaaatg ttttttaggt atatatatat
     1921 ctttagtaaa tttcttgttg tctggtgtta caaatccaaa agttttactt gattggaagg
     1981 tacctactat tctagttatt tctctcttta ttacttttac tattcttcct tctgctctct
     2041 tttcttcagt tgcaggtact actatttctg ccataactct atcattatgc atagcaccat
     2101 ttatattgtc acttgagata aataaatcct gtgtatattc aacatcagat tctacaaatc
     2161 caaaaccctt tttgtgtgat acaaattttc caacaaagta tcccatttga ttgggagata
     2221 ctatttttcc ttttttagta aagcagatat aaccatcttc ttctaattca tttaaaaaat
     2281 tataaaacat tggcatttct gatgaatgta tatcaaatat ttctgctaat tcttcttttt
     2341 ttagaggatt atatgcactt tcatttatta atcctagcaa actttcttta agtcctggta
     2401 tcatttttcc ctcctgtttt acttttcatt atattattat ttatattgtc ttttatattt
     2461 cttcagacaa aacatttttt acttatcaca taattttcta tatttcctta ttattattac
     2521 aagttaaaat tacttattta tatttttgat ttaatgtagc tttgtcatac taacttcaaa
     2581 caaattatga tgttttataa attatttgta aatatcatta taattactta agttattctt
     2641 tatcataatt gcttaaatta ctctttatca cctaattata caccatcaaa taggattggt
     2701 aaaatattca tctcatataa gtattactat ataataattt attctattag tatactcaaa
     2761 tcatgtaaaa tttatataac tcaattaatt ttttaaatac aactttataa tataaaactt
     2821 ataataaaag taaatttata tgttaaatga ggttgatttt ttattatttt ttatttatgc
     2881 tagtactaaa gacttgcaaa cgttttttga caagtcttta ttttgtctaa attaaacaaa
     2941 cttttttaca aataaataca taaaatttaa actaatctat ttattggagg agataaaatt
     3001 ggaagaagta attgcaaaaa ttattactat agaaaatgga ttcaaagaaa ttgaaaacat
     3061 tgctaaaaaa attgtaaaaa ataatgactc aaaaaagtgt tattatctat caatctactt
     3121 atataggtca gaatattatc aagtaagaga attggctgtg tttatacttg gttttatatc
     3181 agtaactatt tctgaagctt tgttattttt aaaagataat gtgagtaaag atgaaaactg
     3241 gagagtacaa gaaatactag ctaaatcatt tgattattat tgcagtgaag taggatatga
     3301 aaaggcactt cctgttataa aagaatggct taattctgat agtccaaaca taaaaagggc
     3361 tgtgacagaa ggtcttcgaa tttggactag tagagactat tttaaatcta atcctgacgt
     3421 tgctatatca ctactttcta gtttaaaaga agatgatagc gaatacttga gaaagtctgt
     3481 aggtaatgct cttagagaca taagtaaaaa atatccagat ttagtaaaaa aagaattaga
     3541 ttcatgggat atatcaaata aaaaagttga gtttgtatat aagcttgctt caaaatgtat
     3601 cttggcaaag taaaatggag gtgaacttat ttgaaacttc gtgatgagta tacttgccca
     3661 ttagaactaa cacatgatat gataaaaggc aaatggaaat ctattatatt atggagatta
     3721 cgcataggac caacttcctt atcaaaactt gaaaaggaaa tcaatggtat taatcaaaag
     3781 atgttacttg aacaacttaa agaattaatt gaatttggtc ttgtagataa aaagacatat
     3841 gaaggttacc cacttaaagt tgaatactca cttacaccta ttcgagggaa acaaatattg
     3901 gatgctttgg ctataatgca agatatagga attagcttta tgttggataa tggtatgcaa
     3961 gatattctta aggaaaaagg tgttttaaaa taaatagata cccacaaaaa agtaagtaat
     4021 ttaccattat tttcaactgg tatataatta aattatagat atattctatt aatttattat
     4081 aataggaggt aaattattat gaaagtaact agtacaggta tagtaaatgg tgttatagaa
     4141 gataaatacg gtaaaagagg aactcagttc aatgaaggtg gtatgcctac atattcacta
     4201 cctctaaagt ttgaagatgc tccaaagaat acagtatcct ttgctgtatt tttagaagat
     4261 aaagactctg ttcctgtatg tgggtttgca tggatacatt ggttagctgt aaatataaca
     4321 aaagatgagt taaatgaaaa tgaaagtgta acagctactg attttgtaca agggactact
     4381 agttggcatg gcaaactagg aggtcttgac agattagagg ccagtgtata tggtggaatg
     4441 gctcctccag acagacctca tgtctatgaa atacatgtat ttgcacttga tactatcctt
     4501 gaccttgaaa aaggattcta tatgaatgaa tttttcaaag ctattgaagg gcatgtttta
     4561 gatacattta cactaaaagg aagttattct aattaattag gttgactata gctaatcatt
     4621 aattaaatgc tacatttaat tgatgattag cttaattgtt attagaatat tttctgcact
     4681 ttatcttaat atatatttta gttgactggt attttaattt atattagatt attatcaatt
     4741 tatataaatt gattttagct taaaacttac ttatctattt cagtttctat tagaattatt
     4801 attagactca ttaaaataaa agcactaata taactaataa tatatgttaa attcattaac
     4861 tctacataaa gttttataat ctaaatgaaa tac
//
LOCUS       DAEORM030000121         4766 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.127, whole genome shotgun sequence.
ACCESSION   DAEORM030000121 DAEORM030000000
VERSION     DAEORM030000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4766)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4766)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 4766)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4766
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.127"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            34..432
                     /locus_tag="KRH23_003748"
     CDS             34..432
                     /locus_tag="KRH23_003748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HHS5227011.1"
                     /translation="MIKKIEHVVITNNNIENYINFYKKFGFSSKEMSKKYKLNARNVK
                     INLNIKGYKFLPYVKNLQASRDNLCFKINTNIDEPKKYLEQNEIQIERGIVECTGVFG
                     NMKSIYLKKTNGNLIELSNHRITESKPWKI"
     gene            420..1358
                     /locus_tag="KRH23_003749"
     CDS             420..1358
                     /locus_tag="KRH23_003749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HHS5227012.1"
                     /translation="MENLILSINVVLPLFLTMSLGYVLKKLGLFDTHTLNKMNNVCFK
                     SFLPLLLFFNIYNTDLDGSLNFKLMAVAVIIIFSIFLILVFIIPKIEKDNKTRGTLIQ
                     GVFRSNFVIFGIPVTISLFGDKSIGVTSLLIAVIVPMFNVLSVVILEIFRGGKVNIKH
                     MIKSVLTNPLIIASFIGLTMLILNINIPTFLHKTIGDISKIATPLSLIILGGSFSFSA
                     IKGHIKPIILGVCGKLILVPAIFLPISIFLGFRNVELASLMIMLSAPTAVSSFTMAQQ
                     MDSDSELAGQIVVFTSGFSIITVFLIIFILKQNNLI"
     gene            complement(1725..1949)
                     /gene="secG"
                     /locus_tag="KRH23_003750"
     CDS             complement(1725..1949)
                     /gene="secG"
                     /locus_tag="KRH23_003750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015136 - sialic acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015739 - sialic acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HHS5227013.1"
                     /translation="MSNILMGVQVVLGILLVISIMPQDSKNALPSEFGGEGSQAYFKP
                     KGKQAFLARVTKITAVLFFINALALLIVKK"
     gene            complement(2061..2570)
                     /locus_tag="KRH23_003751"
     CDS             complement(2061..2570)
                     /locus_tag="KRH23_003751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase family protein"
                     /protein_id="HHS5227014.1"
                     /translation="MNLEIIRATGENATEMGFIHSYSWKKAYKGIIPDNIIDEFTSEK
                     RAEIFHNVIPKAEEEYYLFKVDGIPAGFASLNKSHEENAPKYIGEIYSIYFHPDFWGT
                     PVTKKGLQFCIDRLRNLGYSYITIWVLKDNTRAIKFYKKNGFTCDDFEKEIYIGKKLL
                     EIRYSKKIQ"
     gene            2656..3081
                     /locus_tag="KRH23_003752"
     CDS             2656..3081
                     /locus_tag="KRH23_003752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HHS5227015.1"
                     /translation="MNAIKELSNLWHIVGMQMKTEMCSGKYPTIYGISLVELSILEIV
                     EQHPNSMMKEISSTLELPKSTLTSAVKRLELKKLIKRNPCIKDKRAYNLDLTELGLKA
                     QQEHREIEATVFKNILHQLDKDEIETFIHIFSKAVNKIR"
     gene            complement(3181..4473)
                     /gene="eno"
                     /locus_tag="KRH23_003753"
     CDS             complement(3181..4473)
                     /gene="eno"
                     /locus_tag="KRH23_003753"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000015 - phosphopyruvate hydratase
                     complex [Evidence IEA];
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004634 - phosphopyruvate hydratase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HHS5227016.1"
                     /translation="MSVIELVYAREVLDSRGNPTVEVEVVLEDGAMGRAIVPSGASTG
                     AFEAVELRDGDKGRYLGKGVETAVANVNEIIAPEIEGMDAFDQPAIDAIMIELDGTPN
                     KGKLGANAILGVSMAVARAAADEIGLPLFQYLGGVNAKQLPVPMMNILNGGEHADNNV
                     DVQEFMILPVGACCFKEGLRMGAEVFHSLKKVLGEKGLACGVGDEGGFAPNLGSNREA
                     LELIVEAITKAGYKPGEDVMLGLDVAATEMYNKETKKYVLAGEGKELTAAEMVALYED
                     WSNNFPIITIEDGLDEEDWDGWKLLTEKLGNKLQLVGDDLFVTNTERLEKGIENGVAN
                     SILVKVNQIGTITETLDAIEMAKRAGYTAVISHRSGETEDSTIADLAVAVNAGQIKTG
                     APSRTDRVAKYNQLLRIEEMVGEQARYCGLKSFYNLKK"
BASE COUNT         1634 a          766 c          576 g         1790 t
ORIGIN      
        1 taactaattt atataaaatc ttaaggagtt gccatgataa aaaaaataga acatgtggtc
       61 attactaata ataatataga aaattatatc aatttttata aaaaatttgg tttttcatct
      121 aaagaaatga gcaaaaagta taaacttaat gctagaaatg ttaagataaa tcttaacata
      181 aaaggttata aatttttacc ttatgttaaa aatttacaag caagtagaga taacttatgt
      241 tttaaaataa acacaaatat tgatgagcca aaaaaatact tagaacaaaa tgagattcaa
      301 attgagcgag gaattgtaga atgtacaggt gtctttggta atatgaaatc tatttatttg
      361 aaaaaaacta atggaaattt aattgaatta tcaaatcata gaatcacgga gagtaaacct
      421 tggaaaattt aatcctatca ataaatgttg ttcttccttt gtttctcaca atgtcacttg
      481 gatatgttct aaaaaaatta ggtctatttg atactcatac tttaaataaa atgaataatg
      541 tctgcttcaa gtctttcttg ccattattat tattttttaa tatatacaat acagatttag
      601 atggttctct taattttaag cttatggctg tagctgttat aattattttt tcaatcttct
      661 taatcttagt ctttattatt cctaaaattg aaaaagataa taagacaagg ggtacattaa
      721 tacaaggtgt atttcgtagc aatttcgtta tatttggtat tcctgtgaca atttcactat
      781 ttggcgataa gagtattgga gtcacatctt tattaattgc agttattgta cctatgttta
      841 atgtattatc tgttgtaatt cttgaaattt ttagaggtgg caaagtaaat ataaaacata
      901 tgattaaaag cgtcttaaca aatccactca taatcgcctc ttttatagga ttgacaatgc
      961 taattttaaa tattaatata cctacatttt tacacaaaac tattggtgat atttctaaaa
     1021 tagctactcc tttatcactt ataattctag gcggctcttt tagtttttct gctataaagg
     1081 ggcatataaa acccattata ttgggcgtat gtggaaaact tatacttgta cctgctatat
     1141 ttttaccaat tagcattttt cttggattta gaaatgtaga attagcttca cttatgataa
     1201 tgttatctgc tccaactgca gtttcttcat ttacaatggc acaacagatg gattctgaca
     1261 gtgaattagc tggacaaatt gtagtattta cttctggatt ttctataatt acagtatttt
     1321 taataatatt tattttaaag cagaataatc ttatttaatg atatttgata acacaaattg
     1381 gtattatgag aaacatatat aaaattgatt taattgcgta aaaacatatt attatactat
     1441 ttttactata taatataact ttgtgtatat tatctcatta aacatggtga aagtagtgtt
     1501 gctatatatt ttttagtttg aaaaaaatat ataaatacaa ataataaacg ccaacaaata
     1561 gtcaatctat aaaataaaaa ctggactaat catataaaat cattagtcca gcttttattt
     1621 tacgtacttt ttatgttgat gtacttttat taaaaactaa atttaatttt taagtgtcta
     1681 gcaaatgcac taattaaata atggccagtt attcaacaat atcactactt cttaactata
     1741 agtaatgcca atgcatttat aaaaaataat actgctgtta tctttgtaac tctagcaaga
     1801 aatgcttgtt ttccttttgg tttaaagtaa gcttggcttc cttctccacc aaactctgaa
     1861 ggtaaagcat tctttgaatc ttgaggcatt atgctaatta ctagtaaaat ccctagtact
     1921 acttgcacac ccattaaaat gttgctcatt cttgcccctc ctatctgttt attacttaaa
     1981 tttcattact ctttagtgta tcacaataat atagccattt caagactatt atgctataaa
     2041 tcacatataa aaatatataa ttactgtatc ttttttgagt aacgtatttc taataatttt
     2101 ttcccaatat atatctcttt ctcaaaatca tcacaagtaa aaccattttt tttgtaaaat
     2161 tttatagctc tagtattatc ttttaagacc catattgtta tatacgaata tcctaaattt
     2221 cttagtctat caatacaaaa ttgtaatcct ttttttgtaa caggagttcc ccaaaaatct
     2281 ggatggaaat atatagagta tatttctcca atatattttg gagcattttc ttcatgactt
     2341 ttatttaatg aagcaaaacc agcaggtata ccatccactt taaaaagata gtattcctct
     2401 tcagcttttg gaataacatt gtgaaaaatt tctgctcttt tttcagaagt gaactcatct
     2461 attatattat ctggaataat tcctttatac gcttttttcc atgaataaga atggataaaa
     2521 cccatttctg tagcattttc acctgtagct cgtataatct ctaaattcat aaaaaccacc
     2581 atcctattga caaattaata cgactatcgt attatattag tactataatc gtatcataat
     2641 tggaggtaaa tgtcaatgaa tgctataaaa gaactaagca acctatggca catcgttggt
     2701 atgcaaatga aaacagaaat gtgtagtggt aagtatccta ctatttatgg tatttcttta
     2761 gtagaattaa gtattttaga aatagttgaa caacacccaa atagtatgat gaaagaaatt
     2821 agttcaactt tagaattacc aaaaagcaca ttaacaagtg ctgtaaaacg tcttgaatta
     2881 aaaaaactta taaagagaaa tccttgcatt aaagataaaa gggcgtataa tttagattta
     2941 actgaattag gtttaaaagc tcagcaagaa catagagaaa tagaagcaac tgtatttaaa
     3001 aatatcctac atcaattaga taaagatgag atagaaacat ttattcatat tttttctaaa
     3061 gctgtgaata aaattaggta ataaaatata aaaaggataa gtgaattgaa aaatcaacta
     3121 acacttatcc ttatataaga caaacttaaa cgttttatac tatctcttta atcttaataa
     3181 ctattttttt aagttgtaga aagattttaa tccacagtat ctagcttgct ctccaaccat
     3241 ttcttctatt cttaataatt ggttgtactt agcaactcta tcagttcttg atggagcacc
     3301 agtttttatt tgaccagcat ttactgcaac agctaaatct gctatagtag aatcttcagt
     3361 ttctcctgat ctgtgagata taacagcagt atatcccgct ctcttagcca tttctatagc
     3421 atctaaagtt tcagttattg tacctatttg attaacttta actaatatag agttagctac
     3481 tccattttca attccttttt ctaatctctc tgtgttagta acaaataagt cgtcaccaac
     3541 taattgtaat ttattaccta atttttcagt taataatttc catccatccc aatcttcttc
     3601 gtctaaacca tcttctatag ttattattgg gaagttgttt gaccaatctt catataaagc
     3661 aaccatttca gcagcagtta actcttttcc ttctcctgct aaaacgtatt ttttagtttc
     3721 tttgttgtac atttctgtag cagcaacgtc aagacctaac ataacgtctt cacctggctt
     3781 atatccagct tttgttatag cttcaactat taattctaaa gcttctctgt ttgaacctaa
     3841 gtttggagca aatccacctt cgtcacctac accacaagct aatccttttt ctcctaaaac
     3901 tttctttaat gaatggaata cttctgctcc cattcttaaa ccttctttga aacaacaagc
     3961 tcctactggt aatatcataa attcttgaac atcaacgttg ttatcagcat gctctccacc
     4021 gtttaatatg ttcatcattg gaacaggtaa ttgtttagca tttactccac ctaagtattg
     4081 gaataatggt aaacctattt catcagcagc tgctctagct actgccattg aaacacctaa
     4141 tatagcatta gctcctaatt tacctttgtt tggagttcca tctaattcta tcatgattgc
     4201 atctatagct ggttggtcaa atgcatccat tccttctatt tcaggtgcta ttatttcatt
     4261 tacgttagca acagctgttt ctacaccttt tcctaagtat cttcccttat ctccatctct
     4321 taattcaaca gcttcaaaag ctcctgtaga tgctcctgat ggaactattg ctcttcccat
     4381 tgctccatct tctaatacta cttcaacttc tacagttgga tttcctcttg agtctaatac
     4441 ttctctagca tatactaatt caataactga catttgtata tctcccttcg attttctatt
     4501 agttaaattt tcatttactg taaacatccg tctactattt taatctactt tctatattat
     4561 agtacataaa gttgcttttg aaaattaggt acaaatttat ttgatgggta aatttgtaaa
     4621 agttcctatt tttattttat tttttataat attttaattt atataatata aaaaaacttg
     4681 tctaaaatcc aaaaccaatc ttaaatacac aaatattata actagattta aaacattaaa
     4741 cataaaatgt acaactaatg attcta
//
LOCUS       DAEORM030000122         4641 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.128, whole genome shotgun sequence.
ACCESSION   DAEORM030000122 DAEORM030000000
VERSION     DAEORM030000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4641)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4641)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 4641)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4641
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.128"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            complement(122..925)
                     /gene="proC"
                     /locus_tag="KRH23_003754"
     CDS             complement(122..925)
                     /gene="proC"
                     /locus_tag="KRH23_003754"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004735 - pyrroline-5-carboxylate
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HHS5227017.1"
                     /translation="MKTLGFIGSGNMGSAMIGGIVQSGLVKAEDITVSDLSQVALDKV
                     KEEFGVNTTTDSKVAVTNSDVVIVALKPNICEKALTPLKELIDANKIIVSIAAGKTIE
                     SLESFIGSDKKIVRVMPNTPALVGEGMSALCKNSNVTDEELNMIKALFESFGEAEIVS
                     EYLMDTVTGISGSSPAYVFMFIEAMADAAVLAGMPRQQAYKFASQAVMGSAKMVLETG
                     KHPGELKDMVCSPAGTTIEAVKVLEEEGFRAAVIKSIVACIDKSKDMSK"
     gene            complement(1250..3619)
                     /gene="hypD"
                     /locus_tag="KRH23_003755"
     CDS             complement(1250..3619)
                     /gene="hypD"
                     /locus_tag="KRH23_003755"
                     /EC_number="4.2.1.172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0019471 - 4-hydroxyproline metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trans-4-hydroxy-L-proline dehydratase"
                     /protein_id="HHS5227018.1"
                     /translation="MARGTFERTKKLREESINAEPHISIERAVLMTEAYKKYEGSVEI
                     PVLRALSFKHYIENRTLSINDGELIVGEKGDSPNGAPTYPEICCHTMEDLEVMHNRDI
                     INFSVSEEARKIHKEEIIPFWKKRQTRDKIINAMTPEWLAAYEAGMFTEFMEQRAPGH
                     TVCGDTIYKKGFLDLKKDIEARLKELDFLNDLDAYNKKADLEAMAIACDAMVILGKRY
                     AEKARQMAEEETDEAKKKDLLLIAETCDVVPAHKPETYHQAIQMYWFVHIGVTTELNI
                     WDAFTPGRLDQHLNPFYERDVENGILDRDRAQELLECLWVKFNNQPAPPKVGITLKES
                     STYTDFANINTGGINPDGQDGVNEVSYIILDVMDEMKLIQPSSNVQISKKTPQKFLKR
                     ACEISRKGWGQPAFYNTEAIVQELMEAGKTIEDARLGGTSGCVETGCFGKEAYVLTGY
                     MNIPKILELTLNNGYDPISKKQIGIETGDPRNFQSYEELFEAFKKQLHYMIDIKIEGN
                     AVIENICAKHMPCPLMSTIVDDCIEKGKDYQRGGARYNTRYIQGVGIGTITDSLTAIK
                     YNVFDKKKFDMDTLLKALDANFEGYEAILNLVSNKTPKYGNDDDYADEIMQEIFNAYY
                     NEVTGRPTVCGGEYRVDMLPTTCHIYFGEIMGASPNGRLCAKPVSEGISPEKGGDTNG
                     PTAVIKSCAKMDHIKTGGTLLNQRFAPSVVQGEKGLDNMANLVRAYFNMDGHHIQFNV
                     FDKNVLLEAQKNPQDYKDLIVRVAGYSDHFNNLSRTLQDEIIGRTEQTF"
     gene            complement(3624..4532)
                     /locus_tag="KRH23_003756"
     CDS             complement(3624..4532)
                     /locus_tag="KRH23_003756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0019471 - 4-hydroxyproline metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trans-4-hydroxy-L-proline dehydratase activase"
                     /protein_id="HHS5227019.1"
                     /translation="MNPLVINLQKCSIHDGPGIRSTVFFKGCPLECVWCHNPESQTYT
                     KQVLYNEERCSKCEACINICPHKAIYKGETKICLDQDKCEFCETCLDYCVNNAREIVG
                     QEYSVRDLVKEIEKDRIFYEESGGGVTLSGGEVMAQDMDFICGVINMCKSKGIHVAID
                     TCGYAKSENYERVAKCADLFLYDIKLIDEDKHIKFTGKSNDLILKNVKILSELGANIN
                     IRIPLIVGVNVDDENLEVKKMIEFLKPLNIQAVSLLPYHNIGKHKYDKIYKKYEGEEL
                     QRPSEEKLEEIKRLFEASNFNTKIGG"
BASE COUNT         1366 a          905 c          506 g         1864 t
ORIGIN      
        1 taaattcatt tttatagtaa attactctta ttttacttat accaaataca tttatgtata
       61 gatataaata agcactaaaa aaacaattca agaaaccata tagtaaactt aattacatct
      121 gttatttact catatcttta gacttatcta tacaagcaac aatagatttt ataactgctg
      181 ctctaaagcc ttcttcttct aataccttaa cagcttctat agtagttccc gctggagaac
      241 aaaccatatc ttttaattca cctggatgtt ttccagtttc aagaaccatc ttagctgacc
      301 ccattactgc ttgagatgca aatttataag cttgttgtct tggcattcca gctaatactg
      361 ctgcatctgc catagcttct ataaacataa atacatatgc aggagaagaa ccactaatac
      421 ctgtaactgt atccattaaa tattctgata ctatttctgc ctcaccaaaa gattcaaaca
      481 gagccttaat catatttaac tcttcatctg ttacattact atttttacaa agagctgaca
      541 ttccttcgcc aacaagggct ggagtattag gcattactct tactattttt ttatctgaac
      601 ctataaaact ttccagactt tctatagttt tacctgctgc tatagatact attattttat
      661 ttgcatctat taattcttta agtggagtta aagccttttc gcatatatta ggtttaagtg
      721 ctactattac cacatcagaa tttgtaacag ctacctttga atcagttgta gtatttactc
      781 caaattcttc ttttacttta tctaaggcaa cttggcttaa atctgataca gttatatctt
      841 ctgcctttac taatcctgac tgtactatgc cacctatcat tgcacttccc atattccctg
      901 aaccaataaa tcctaaagtt ttcatatcaa atctcctttt ttctattagt tttattttaa
      961 agtagctaaa ttgactttat tttaactgct taaaattatc ttatttttat aaaatataac
     1021 cttattataa ctataataaa ttattctttt gtatgtatta cttactaata tgtgtatgat
     1081 ttactaaata taaatttaac gattttttca ttaaacttaa cgagctaact tcctatttag
     1141 aaagttagct cataattaat ctaaaatttt aaaaatggaa tcaaaccatt tatactttat
     1201 tatatcagtt acgattttat atagtaagaa gttttattta caagcaaacc tagaatgttt
     1261 gctcagttct tcctattatc tcatcttgta gtgttctact taaattattg aaatggtcac
     1321 tatatcctgc aactctaact attaagtctt tataatcctg aggattcttt tgagcctcta
     1381 acagtacatt tttatcaaat acattaaatt gtatatgatg accatccata ttaaagtatg
     1441 ctcttactag attagccata ttatctaacc ctttttctcc ttgaactact gatggtgcaa
     1501 atctttgatt taataatgtt ccaccagttt ttatgtggtc catcttagca caagatttta
     1561 taactgctgt aggtccatta gtatctccac ctttttcagg tgaaattccc tctgaaactg
     1621 gttttgcaca aagtctacca tttggacttg ctcccataat ttctccaaag tatatatgac
     1681 aagttgttgg taacatatct actctgtatt ctccaccaca aacagttggt ctaccagtta
     1741 cctcattgta atatgcattg aatatctctt gcattatttc atcagcataa tcatcatcat
     1801 ttccatattt aggagtctta tttgaaacta aattaagtat agcttcatat ccttcaaaat
     1861 tagcatcaag tgctttaagc aatgtatcca tatcgaattt tttcttatca aatacattat
     1921 attttattgc tgttaaacta tctgttatag ttcctatacc aacaccttgt atatatctag
     1981 tgttgtatct tgctccacct ctttggtaat ccttgccttt ttctatacaa tcatcaacta
     2041 ttgtagacat aagtggacaa ggcatgtgtt ttgcacatat attttctatc acagcatttc
     2101 cttctatttt tatgtcaatc atataatgta attgcttttt aaatgcttca aatagttcct
     2161 cataagattg gaaatttcta gggtctccag tttcaatacc tatttgtttt ttactaattg
     2221 ggtcatatcc attatttaat gttaattcaa gtatttttgg aatgttcata tatccagtta
     2281 gaacatatgc ttctttacca aaacatccag tttcaacaca accactagtt ccaccaagtc
     2341 ttgcatcttc tatagttttt ccagcttcca taagctcttg aactattgct tcagtattat
     2401 aaaatgctgg ttgaccccat ccttttcttg atatttcaca agctctcttt aagaattttt
     2461 gaggagtctt tttacttatt tgaacatttg aactaggttg tatcaatttc atttcatcca
     2521 taacatcaag tattatataa ctaacttcat taacaccatc ttgaccatct ggatttattc
     2581 caccagtgtt tatatttgca aaatctgtat atgtgctact ttcttttaat gttataccaa
     2641 cttttggtgg tgctggctga ttgttaaatt taacccataa acattcaagt aattcttgtg
     2701 ctctatctct atctagtatt ccattttcta catctctttc atagaaagga tttagatgtt
     2761 ggtcaagtct tcctggagta aaagcatccc atatattaag ttcagtggta acccctatat
     2821 gaacaaacca atacatttgt atagcttgat gataagtttc tggtttgtga gctggtacaa
     2881 catcacaagt ttcagcaatt agtaataaat cttttttctt agcttcatct gtttcttctt
     2941 ctgccatttg tcttgctttc tcagcatatc ttttacctaa tataaccatt gcatcacaag
     3001 ctattgccat agcttctaaa tctgcttttt tattatatgc atctaaatca ttaagaaaat
     3061 ctagctcttt taatcttgct tctatgtctt tctttaaatc taaaaatcct tttttatata
     3121 ttgtatctcc acaaactgta tgtcctgggg ctctttgttc cataaactct gtaaacatac
     3181 ctgcttcata tgctgctaac cactcaggtg tcattgcatt tattatctta tctcttgttt
     3241 gtctcttttt ccaaaaagga attatttctt ctttatgtat ttttctagct tcttctgata
     3301 cgctaaaatt tattatatct ctattgtgca ttacttctaa atcttccatt gtatgacaac
     3361 aaatttctgg atatgttggt gctccattag gagaatcacc tttttcacct actattaatt
     3421 ctccatcatt tatactaaga gttctattct caatataatg cttaaatgat aaagcacgaa
     3481 gtacaggaat ctctacactt ccctcatatt ttttataagc ttctgtcata agtactgctc
     3541 tttcaataga tatgtgtggt tctgcattaa tactttcttc tcttaatttt ttagttctct
     3601 caaaagttcc tcttgccatt ttattaccct ccaatcttag tattgaaatt acttgcttca
     3661 aacagtcttt ttatttcctc taatttttct tctgatggtc tttgtagttc ttctccttca
     3721 tactttttat aaattttatc atacttgtgt ttaccaatat tatgatatgg aagaagactt
     3781 actgcttgta tattcaaagg ctttaaaaac tctatcattt ttttaacctc taaattttca
     3841 tcatctacat ttactcctac aattaatggt attcttatat ttatgttagc ccctaattca
     3901 cttaaaatct taacattttt cagtattaag tcatttgatt ttcctgtaaa ttttatatgc
     3961 ttatcttcat caataagctt aatatcatat aaaaacaaat ctgcacattt agcaactctt
     4021 tcataatttt ctgactttgc atagccacat gtatcaattg ctacatggat tccctttgat
     4081 ttgcacatgt ttattactcc acaaatgaag tccatatctt gagccattac ttctccacct
     4141 gatagagtta ctccaccacc tgattcttca tagaaaattc tatccttctc tatctcttta
     4201 accaaatctc ttacagaata ctcttgacca acaatctctc ttgcattgtt tacacaatag
     4261 tctaagcaag tttcacaaaa ctcacactta tcttggtcta agcatatttt tgtttcacct
     4321 ttgtaaattg ccttatgagg gcatatattt atacatgctt cacattttga acatctttct
     4381 tcattataca aaacttgttt tgtatatgtt tgactctctg gattatgaca ccaaacacat
     4441 tcaagtggac accctttaaa aaatactgta cttcttatcc ctggtccatc atgtatgcta
     4501 catttttgta agtttataac taatggattc atgatttttc acccctaaat aatatccatt
     4561 ccattttttc atttttatgc aattcacctt catacaatat acctatgaaa agcatttcta
     4621 caattacata atactatatt t
//
LOCUS       DAEORM030000123         4585 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.129, whole genome shotgun sequence.
ACCESSION   DAEORM030000123 DAEORM030000000
VERSION     DAEORM030000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4585)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4585)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 4585)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4585
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.129"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     regulatory      complement(166..263)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            504..686
                     /locus_tag="KRH23_003757"
     CDS             504..686
                     /locus_tag="KRH23_003757"
                     /inference="COORDINATES: protein motif:HMM:NF015898.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HHS5227020.1"
                     /translation="MLNKKLPDTELKIMKCIWNTGYKTVISKDVADEIEKTYGWKHTT
                     TIILLARLTKKGFLIS"
     regulatory      1242..1335
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            1418..1903
                     /locus_tag="KRH23_003758"
     CDS             1418..1903
                     /locus_tag="KRH23_003758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0070064 - proline-rich region binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HHS5227021.1"
                     /translation="MISELMLKNFRKSSINFKTKIKLNLREKPDINSLKLKSIPEGKI
                     VKLKCVDGIWAEVESNYDKGWLLYKYLERLSNAKNNSNDTIKNRKKNYIGNIRTNGLS
                     LELRNDRTLESKVITTIPDGFKVEVCYSVGKWARVNINKNEKRYSGYVYNQYIEEHLS
                     L"
     gene            2259..2657
                     /locus_tag="KRH23_003759"
     CDS             2259..2657
                     /locus_tag="KRH23_003759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5227022.1"
                     /translation="MNKKKKLIGIAISFLLIISIINPLQVEAEAIIESSVYISSIKEN
                     YTYDNTKFKTIKSKSRHKSRKYNKSKVKLKKRSIRTKKYGYQTINKYKRQNARRHNIL
                     TKLILSIIVIFLVIVLVVLIFIKRKKKKFY"
     misc_binding    3093..3356
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            3507..4058
                     /locus_tag="KRH23_003760"
     CDS             3507..4058
                     /locus_tag="KRH23_003760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan transporter"
                     /protein_id="HHS5227023.1"
                     /translation="MKTNTKKLTLNAILLAMGLLIHQITPAIGLPMKPDVPLAMLFVI
                     LVLNRDDYKTCLIAGIVTGIFTALTSSFPGGQIPNVIDKTLTANIVFLLMNISYNMPF
                     IKKLAKKTQDTVVVAIIMPIGTLVSGTIFLLAAQAIVGLPGASFTALFLAVVLPAVLI
                     NLVAGIFLFKIVSLSIRRVSYQA"
BASE COUNT         1983 a          418 c          631 g         1553 t
ORIGIN      
        1 ctctaatata aaatcatcta attgtgtatc taaaaaatta caataatcat acgaactgct
       61 aatataagca gtcaatacat gtgtacattt atccatttta tttccaaaca tataaattat
      121 tatcccccta aaaaactttc ataaaaacaa aaagaacact atctctttgg caactggctg
      181 acataactca taagatattt atataagtct tagtccctat agctttgcgt cactaaattt
      241 ctctagtttt gccgatttag ttttattcta caactaaaat aatataatag aattagttat
      301 tattcaacag gattgtttga aagttaaata aatttataga tatgaacatt attttacact
      361 taaaaacaga ctaaacacgt agagtacttg gtaaaaatta aatatagttt ttgttctaaa
      421 aagctcctat tataatttaa gctagataaa tttgaagaag tgacataaga agaagtgaca
      481 taaattgaaa gaaggaatat attatgctaa ataaaaaatt accagataca gaattaaaaa
      541 ttatgaaatg catatggaat actggttata aaactgtaat atcaaaagat gttgcagatg
      601 aaatagaaaa aacatatggt tggaagcata caactacaat tatactttta gctagattaa
      661 ccaaaaaagg ttttttaata tcatagagaa tagggaggca tgtacactat acagtattaa
      721 taaaagagag agaatatctc aaaatagagg gaaaaagagt ttttagaggt ttacataaca
      781 atcctttatc agaattaatt tcaaaattac atgatggaga agaaataact gaagaaaaaa
      841 taatagaaat aggaagttgg ataaaaagct ggaaatataa agattaataa ataaaaggta
      901 gctaataata taagtgctac ctttttatgt ggataatatt ggtgataagt tgtggaaaac
      961 ttatataaaa attgtggata aagtgttttg ctgacatttt actgacaaaa gttaaaaaaa
     1021 taaatgttat atatattgta aaatgttgaa aaatagccat atatataaaa tataagtaac
     1081 actatagata aattactgtc ttttatattg actataaaga acagtaattg aataaatata
     1141 aagatatttt ttgattatta ttaattaaaa atttaattta tatttaaata atataaaatt
     1201 tgaggtaata ttatttttta attgttcaaa ttatgttatt attcagatat aggcaatatt
     1261 agataaatct aatgacgcaa aactataggg actaaaatct ttatgtaata aaggtcatgt
     1321 cagccagttg ccaaaaagat aataattctt tttgttaaaa gtatttttag agttatatat
     1381 tttaataact taatatttgg caagaggagg gcttaagatg atatctgaat taatgttaaa
     1441 aaattttcgc aaatctagca tcaattttaa gactaaaatt aaattgaatt taagagaaaa
     1501 accagacata aatagtttga aattaaaaag tataccagaa ggtaaaattg ttaagttaaa
     1561 gtgtgtagat ggaatatggg cagaagttga gagtaattat gacaaaggtt ggttacttta
     1621 taaatattta gaaagattaa gtaatgctaa aaacaatagt aatgatacaa taaaaaatag
     1681 aaaaaagaat tacataggaa atataagaac aaatggatta agtttagaac ttagaaatga
     1741 tagaacatta gaatctaaag ttataactac aatccctgat ggttttaaag ttgaagtatg
     1801 ttatagcgtt ggaaaatggg caagagttaa tatcaataaa aatgaaaaac gatattctgg
     1861 atatgtatat aatcaataca tagaagagca tttaagttta taatacgata ctagcaagct
     1921 ttaaatatat taataaatca caaaaaagaa tcccattaat gggattcttt tttgtagaaa
     1981 cattataaca gaactaaaga gaataaatta actaatttat ttttattata aagtaattat
     2041 aaatggtaaa tttaattgaa agtagattta acttatactt tatacaccaa gtatcataaa
     2101 ttaatactac tttgaaaaat cttaaaaaaa gtaaaagtta tgataataaa aataatatta
     2161 aagataataa gatatataag aaacttgaaa aaatttgtaa tttttagtta tatatatatt
     2221 ataatgaact agttaaaaat ttttatgagg gggaaaatat gaataagaag aaaaaattga
     2281 ttgggatagc tatatctttt ctacttataa tcagcattat aaatccatta caagtagaag
     2341 cagaagctat tattgagtct agtgtataca tttcttcaat aaaagagaat tatacatatg
     2401 ataatactaa atttaaaact attaaatcta aaagtagaca taaaagtagg aaatataata
     2461 aaagtaaagt aaagttgaaa aaacgaagta taagaactaa aaagtatgga tatcaaacta
     2521 taaataaata taaaagacaa aacgcaagaa gacataatat cctaacaaaa ttaatattgt
     2581 ccataatagt catatttttg gttatagttt tagtagtgct aatatttatt aaaagaaaga
     2641 agaaaaaatt ttactaaaaa taattaaaag aatatcattt ttttaatcat tggtatctat
     2701 ttaataatat gatgtaatta aaatggagta atattctgtt tcaaaggagg catataaata
     2761 caggaatgag tattaaatga tggttaatta agtaaattta ttgataaatg tacttaatta
     2821 actttgaaga atttaattct tcatgaatca aaatataaaa ttacatcaac agttattcac
     2881 aaaattaata taagaagaat tagagccaaa gagcagacta ttagaccatt aaagtaatta
     2941 ttcatagaat tttgtatatg aaaagaaatg tatagtataa tttacttttt ttataaaaaa
     3001 tagattacaa aatatatttt ttataaaaaa gtattgacat tttttagaaa aaagaatatc
     3061 attattttaa caacaaaatt caatacaata aattaaatcc tatgacaagg aagagtagtt
     3121 aaatttaggt tcagtataga gagctgagga tggtggaatc ttagcaagaa aaaatttgat
     3181 gaatggccct tagaggaata aattgaaatc atagttttga gagtagactt tatcgtcagt
     3241 cgcacgttat agcgaataag gtatgtaagt acctgataat gagatgtatg aaaattgaat
     3301 tttatattaa tttttatata atttaggtgg caacgcggat aatctccgtc ctattagttt
     3361 aggacggagt tttttatttt actgaaaatt taaaagatag aaggtggtga gaaagatgtt
     3421 atgaatttca aaagctaaag atgatgatat agtaggttgg caaaaaaata aattgaaaat
     3481 taaaaaaata ggaggaagta caaaaaatga aaacaaatac aaaaaaatta actttaaatg
     3541 caatactttt agcgatggga ttattaatac atcaaatcac accagctata ggattaccaa
     3601 tgaagccaga tgtaccacta gcaatgttat ttgtaatatt ggttttaaat agagatgatt
     3661 ataaaacttg tttgatagcg ggtatagtaa caggaatatt tacagcactt acatcaagtt
     3721 ttccaggagg tcaaattcct aatgtaatag ataaaactct tacagcaaat atagtatttt
     3781 tattaatgaa tattagttat aatatgcctt ttataaaaaa attagctaag aaaacacaag
     3841 atactgtagt agttgcaata ataatgccaa taggaactct tgtaagtgga actatctttt
     3901 tattagcagc tcaagctata gttggtcttc caggggcttc atttacagct ttattcttag
     3961 cagtagtatt accagctgtt ttaataaatc tagttgcagg aatattttta ttcaagattg
     4021 ttagtctatc aataagaaga gttagttatc aagcttaaac acgaaataat attttacttt
     4081 ataaagcatt ataataacta aataacataa gaataaagta gattataact attttattct
     4141 tatgttgttt aaagatttgg tattatatat ttatttttaa taaaatattt atatagtacc
     4201 aattacactt aatttaacag ataaattatc atacctatat aatattctta tatgtatctc
     4261 atttgtagtt attaaatata agatatattt aattgacttt tcaagataaa tttttatatt
     4321 aatctcctct gatttctcat tttttgaata cactaaaatt tccaattaaa tcaattatat
     4381 atttataaag ttttaaaaat atagtaatgt atatattttt tgtgaaaaac ttgcttaaat
     4441 ttagccaaaa aaaatagata attcatagta taaaataaag tttagtaaaa aattttaata
     4501 gaactataaa agtctgtttt agtaaaagat ttaaaattct aatattaagt gaaattttgg
     4561 gtgaattaaa taagcaaaac tataa
//
LOCUS       DAEORM030000124         4499 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.130, whole genome shotgun sequence.
ACCESSION   DAEORM030000124 DAEORM030000000
VERSION     DAEORM030000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4499)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4499)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 4499)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4499
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.130"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            276..581
                     /locus_tag="KRH23_003761"
     CDS             276..581
                     /locus_tag="KRH23_003761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5227024.1"
                     /translation="MPSMIMEVVGVLFIAIGLILTFIEIKGNFPSFYGFGQNSIGKNA
                     VGIIAAGIALIFFRNGIDSIDSIATYGVFLAIELVVIVAYFLIRKKFTKEDKHLRTN"
     gene            989..1678
                     /locus_tag="KRH23_003762"
     CDS             989..1678
                     /locus_tag="KRH23_003762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HHS5227025.1"
                     /translation="MDILLVEDDKNIREMVYDFLISENYSVKTAIDGNTAIEIFKNYS
                     FDIILLDLMLPKSSGFEVLKYIRSVSVVPVIITTAKDSDTDKMLGLNLGADDYITKPF
                     SIVELLARIKANIRRATVYSSSRNSQDMVIQYKDLIINISKYVVSKNGIDLNLTHTEF
                     EIVKLLATNQGRAFSKEQLYNTIWKEPYYGNENVLNTHINRLRNKLSDGIEKNNYIKT
                     LWGIGYKMEEE"
     gene            1678..2595
                     /locus_tag="KRH23_003763"
     CDS             1678..2595
                     /locus_tag="KRH23_003763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HHS5227026.1"
                     /translation="MELFLVVISIVLFALYLKERNKSKKMESDYKYINSRLRDITNDD
                     EINYILVPSDISIVKETAVDINKLLEKFYSRQINYNRSEKAILQIFTNISHDLRTPIT
                     VLKGYIEMLYLQSQKEELSSSMRATVEKMQTNSNELVNSINNLFNMAKIQSGDMILNL
                     QKSNLTQLCHEIILEFYDLLDKENFNVEVNIEDRPIYANVDTEALQRILKNLIDNAIK
                     YGSDGRFLGISLYEKEKHVFIDIEDKGSGISETEKEHIFTRAYTADRKKGNGLGLAIS
                     QGLVNSMGGSIYVNSRPNVKTVFTVKLKS"
     gene            2668..3594
                     /locus_tag="KRH23_003764"
     CDS             2668..3594
                     /locus_tag="KRH23_003764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHS5227027.1"
                     /translation="MNYIIETHQLKKIYKDKAVVNAVNIHVKKGEIYGFVGPNGAGKS
                     TVMKMLLNLVKPNSGEIVMFGKKVAETDFEILKKIGTIIENPYFYENLTAKQNLDLHC
                     EYMGYYNKEHISEVLECVGLSKQSNKKVSKYSLGMKQRLAIARAILTKPELLILDEPI
                     NALDPEGIREMRELFRKLNTDYGITIFISSHILSEVEQIADTIGIIQDGKLIKEISMS
                     DIHKYQTDYVEVDVDNVELAGYLLEKEFGIKDFKITSESCIEIYDLRKDVKEISKIFI
                     QNQIGINSIGRKQSSLEDYFFQTTGTGGIETL"
     gene            3591..4271
                     /locus_tag="KRH23_003765"
     CDS             3591..4271
                     /locus_tag="KRH23_003765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHS5227028.1"
                     /translation="MIHLMKLELKKVGLKRYFLFSILGIFLCMFFVFTGLNDKSTSIY
                     DYDVTFSTISLVFCFYYIILFAVLNVAYIINEYTNKTILILFSYPLDRKKLILSKLLL
                     ITTLMISSMIIGYICCFTFVVVLDKYFNLVIGDFHISILSYWIPGAIKSIIVFCSLGI
                     WTFVVGMIRKSIPVTLVSSIIFINLRQFILAGTNTTQDSLISVFIIVGITVIGIYYIL
                     NHKVTEID"
     gene            4372..>4499
                     /locus_tag="KRH23_003766"
     CDS             4372..>4499
                     /locus_tag="KRH23_003766"
                     /inference="COORDINATES: protein motif:HMM:NF014691.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HHS5227029.1"
                     /translation="MAQPFEVEPKLDELIEWYYSQSEVSIKVIAEFHYRFELIHPF"
BASE COUNT         1739 a          474 c          720 g         1566 t
ORIGIN      
        1 agaagtccat gcttataagc cagaaaatga atactttaat agattaaaaa atacatattt
       61 gtgaattata gaatgaataa ctccataaac tagaaaattt ataataatat ctatatgaaa
      121 attagaatta ttttatcaca aaaaaattaa gttaaataaa tatgaaatta cttccaaata
      181 tacttccaaa aacatgtaat cgcatatata atataattat aaaaataata aatattttta
      241 tagtagtagt taattattaa taaggagggg tcaaaatgcc tagcatgatt atggaagttg
      301 taggagtact atttatagct attggattaa tcttgacatt cattgaaata aaaggaaatt
      361 tcccttcttt ttatggtttt ggtcaaaatt ctatagggaa aaatgctgta ggtattatag
      421 cagcaggaat tgctttaatt ttctttagaa atggcataga tagcatagat tctatagcta
      481 cttatggtgt atttttagca atagaacttg ttgtaatagt tgcatatttc ttaataagaa
      541 aaaaatttac taaagaagat aaacatttaa gaactaatta actaaattat ctactataaa
      601 attggaaaat taaaaacaaa taaaagtttg tttttaatta tttaaaatcc aaatttgatt
      661 atttttaaag aaactgtgtt ctgtataaaa ctagaatgtg gtttcttttt tatgtataaa
      721 atatttttta gcaaaagtta aaaggtgttt tataatataa aatagttaat tgtagatgtt
      781 aataaaagaa aattatgtat atttcagata aagataagag agtatactat attttaattc
      841 ttttttcaat aaagcttatt gaaaagaact ttaacttaga agagtatcac caaattgcag
      901 atacaatatc ataagcagtt atttattgac aacccttttt aataaatata tcatttgaag
      961 tatactgacg aaaaggagtt gaataataat ggacatctta ttggttgaag atgataagaa
     1021 tattcgagaa atggtatacg attttctgat tagtgagaat tactctgtta aaactgccat
     1081 tgatggaaat acagctattg aaatatttaa aaattattca tttgatatta ttttactgga
     1141 cttgatgtta ccaaagtcta gtggttttga agtattaaaa tatatacgaa gtgtgagtgt
     1201 tgttcctgtt attattacta ctgcgaaaga tagtgacaca gataaaatgc tagggcttaa
     1261 tcttggtgca gatgattata ttacaaagcc tttttcaatc gtagaattgc ttgcaagaat
     1321 taaagctaat attagacgtg caacagtgta cagcagttca agaaactctc aagatatggt
     1381 tattcagtat aaagatttga ttataaacat atcaaaatat gtagtttcaa agaatggaat
     1441 tgacttaaac ttaacacata cagaatttga aattgttaaa ttactagcga ctaatcaagg
     1501 acgtgctttt tcaaaggaac aattatacaa cactatttgg aaagaacctt attatggaaa
     1561 tgaaaatgtg ctaaatactc atattaacag gttaagaaat aaattgtctg atggtataga
     1621 aaaaaataat tatattaaaa ctctttgggg aattggctac aaaatggagg aagaataatg
     1681 gagttatttt tagttgtaat ttctattgta ctatttgctc tctacttaaa agaacgaaat
     1741 aagtcaaaga aaatggaaag tgattataag tatatcaatt caagacttcg tgacataaca
     1801 aatgatgatg aaattaatta tattttagta ccatctgata tttcgattgt aaaagaaaca
     1861 gcagtagata taaataaact tcttgaaaag ttttacagca ggcaaattaa ttataataga
     1921 agtgaaaaag cgatattgca aatatttaca aacatatcac acgatttacg aactcccatc
     1981 acagtattaa agggttatat tgaaatgcta tatcttcaaa gtcaaaaaga agaattatct
     2041 tcttcaatga gagcaactgt ggaaaaaatg caaacaaatt caaatgagct tgttaattca
     2101 ataaataacc tgtttaatat ggcaaaaatc caatctggag atatgatatt aaatcttcaa
     2161 aaatccaatc taacacaatt atgtcatgag attattttag agttttatga tttactagat
     2221 aaagaaaact ttaatgttga agttaatatt gaagatagac ctatatatgc aaatgttgac
     2281 acagaagcat tacaacgtat actcaaaaat ttaattgata atgctataaa atatggttca
     2341 gatggtagat ttttagggat ttcactatat gaaaaggaaa aacatgtttt tatagatatt
     2401 gaggataaag gttcaggtat ttctgaaact gaaaaagagc atattttcac aagagcttat
     2461 actgctgaca gaaaaaaagg caatggttta ggtttggcta tttctcaagg gcttgtaaac
     2521 tctatgggag gttcaattta tgtaaatagt agacctaatg taaaaacagt ttttacggta
     2581 aaattgaaaa gttagaaaaa agttagattt aaaagagaga aaagacaatt ttattttgta
     2641 tactgttttt agaaaggagg gagtatgatg aactatatca tagagaccca tcaattaaag
     2701 aaaatatata aagataaagc tgttgttaat gctgttaata ttcatgtgaa aaagggagaa
     2761 atttatggat ttgttggacc aaacggggca ggtaaaagta cagtaatgaa aatgttgcta
     2821 aatcttgtta agccaaattc tggagaaata gttatgttcg gtaagaaagt ggcagaaact
     2881 gattttgaaa tattaaaaaa gattggtact attattgaaa atccttattt ctatgagaat
     2941 ttgactgcta aacagaatct tgatttacac tgtgaatata tgggttatta taacaaagaa
     3001 catatatcag aggtattgga atgtgtcgga ttgtcaaagc aatcaaacaa gaaagtttca
     3061 aaatattctt tagggatgaa acaacgtctt gcaatagcta gagcaattct tactaaacca
     3121 gaattattga ttcttgatga acctataaat gcactcgacc cagaggggat aagagaaatg
     3181 cgagaattat tccgtaagtt aaatacagat tatggaataa ctatatttat ttctagtcat
     3241 attctttcag aggtagaaca aattgcggac actattggaa ttattcaaga tggtaaactt
     3301 attaaagaaa tttctatgtc agatatacac aaatatcaaa cagattatgt tgaagtagat
     3361 gtagataatg tggaacttgc tggatacttg ttagaaaaag aatttggaat aaaagacttt
     3421 aaaattactt cggaaagttg tattgaaata tatgatttac gaaaagatgt aaaagaaata
     3481 tccaaaatat ttattcaaaa tcaaattggt ataaatagca ttggacgtaa acaaagttct
     3541 ttagaagatt acttcttcca aactacaggt acaggaggta tagaaacact atgatacatt
     3601 taatgaaact agaattaaaa aaagttgggc taaaaagata ttttttattt tcaatactgg
     3661 ggattttctt atgtatgttt tttgtcttta ctggattgaa tgataaatct acttcaatat
     3721 atgattatga tgttacattt agtacaatca gtttagtttt ctgtttttac tatattatat
     3781 tatttgctgt gttgaatgtg gcatatataa taaatgaata tacaaataaa acaatcttga
     3841 ttttattctc ttatccactt gaccgtaaaa aacttatttt atcaaagtta cttttgatta
     3901 cgactcttat gatatcatca atgataattg gatatatctg ttgttttaca ttcgttgttg
     3961 tgttggataa gtactttaat ttagttattg gagattttca tatttcaatt ttatcttatt
     4021 ggataccagg agcaattaaa agtattattg tattttgctc attaggtata tggacattcg
     4081 ttgttggaat gataagaaaa tcaatacctg ttacccttgt cagttcaatt atttttatca
     4141 atttaagaca atttatttta gctggtacaa atacaactca agacagtttg atttctgttt
     4201 ttattatagt tggtataact gtgattggta tatattatat actaaatcat aaagttactg
     4261 aaattgacta gatactgtgg ctaggaaggt agttattaat tgtatcttct tgggataata
     4321 atgatttgct attatatcag ctattattaa tattattaga gttttaataa tattgcacaa
     4381 ccatttgaag ttgagccaaa gcttgatgaa ttaattgaat ggtactatag tcagagtgaa
     4441 gtatctatta aagttatagc tgaatttcat tatagatttg aattgataca tccatttca
//
LOCUS       DAEORM030000125         4485 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.131, whole genome shotgun sequence.
ACCESSION   DAEORM030000125 DAEORM030000000
VERSION     DAEORM030000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4485)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4485)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 4485)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4485
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.131"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     misc_binding    78..312
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            362..1381
                     /gene="pheS"
                     /locus_tag="KRH23_003767"
     CDS             362..1381
                     /gene="pheS"
                     /locus_tag="KRH23_003767"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006432 - phenylalanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HHS5227030.1"
                     /translation="MQEKLLALREAALAEIKEAQSIESVESLRVKYLGKKGEITAILK
                     EMGKLSAEERPVVGKVANEVRENIELSINSKKEEINAIEKERKLKEEVIDVTQPGKVL
                     KVGKKHPITQIIDEVTDIFIGMGFSIAEGPEVETVENNFDALNAPKDHPSRDMSDTFY
                     INDGVLLRTQTSPVQVRTMRSQELPIKVIAPGRCFRSDSPDATHSPMFHQIEGLVVGK
                     DVTMAEFKGTMDIFVEKLFGSDIKTKFRPHNFPFTEPSAEVDVTCFKCGGKGCPMCKY
                     EGWIEILGSGMVHPNVLRNCGIDPEVYSGFAFGVGVERLAMLKYEIDDIRLLFENDMR
                     FLNQF"
     gene            1398..3791
                     /gene="pheT"
                     /locus_tag="KRH23_003768"
     CDS             1398..3791
                     /gene="pheT"
                     /locus_tag="KRH23_003768"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006432 - phenylalanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HHS5227031.1"
                     /translation="MLVSLKWLRDYVDIDMDVKEFADKMTMTGTKVETIDYYGEEIEN
                     ILVGKILEIKQHPNADKLVVTKVDIGDKVVQIVTGATNISEGDYIPVAVNGSKLPGGV
                     EIKQTDFRGELSDGMMCSAAELGIDEHYIEEYKRGGIYILDHEDSYELGKDIKDVLGL
                     KDALIDFELTSNRPDCKCMMGIAREAAATIGTKVKYPEIEVKESDEEIDFKVEIDNPD
                     LCRRYVARMVTDVKIEPSPYWMQRRLTEAGVRPISNIVDITNFVMLELGQPLHAFDIN
                     QVETGRIVVRNAKDGEKLVTLDDVERTLDKDMLVITNGEKSLGLAGVMGGANSEITSN
                     TKTVLFESANFKPENIRMTAKKVGIRSEASSRNEKDLDPNLAEIAANRAAQLVEMLGA
                     GKVLKGVVDVYPNKPEPKKLVVNPQRINHLLGVDVPMEQFVGILESLEFKCNLVANDK
                     LEIDVPSFRTDMEQEADVWEEIARIYGFENIPSVQLEGNTTAGIKTSKQKFMDALKDN
                     STAVGLNEILTYSFVSPKGVDKIRVPEGNAKRNFVKLLNPLGEETSVMRTTLIPNMLD
                     VLSTNVSHKIEEVSAFECGHIFIPQDSELPKEENRMCVGMYGKDVDFFALKGTIETIL
                     VNVGFKGYEIEPQDNNTTFHPGRCAKIVYNNKYVGTLGELHPDVIENYNLGQRVYVAE
                     IDIDFVFDNSDRTKNYVPLPKYPSTSRDIALIVKDDVFVKQIEDIIKENGQGLVESYK
                     LFDVYKGSQIEAGYKSIAYSITYRSKDKTLTDEDVAKVHDKILSELSEKLNANLRSN"
     gene            3815..4405
                     /gene="zapA"
                     /locus_tag="KRH23_003769"
     CDS             3815..4405
                     /gene="zapA"
                     /locus_tag="KRH23_003769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HHS5227032.1"
                     /translation="MNKVMVKIHGAEYPMVGDKSEKFMISIADFVDKEMDKITRQNPK
                     LSLSVAAILTALNISDLLFECSDENEKLIKANEELSKKVGASNEELQLEIKSLKLTIA
                     EKEAENREAETKMKELIEIIENKKQEIFELSNTTEGSRAELDAYKNKIEELSTQLEEA
                     NERATIAENLASEFQNKAYDLQLKCTGLNNDAKNVE"
BASE COUNT         1770 a          522 c          919 g         1274 t
ORIGIN      
        1 tgtattggat atatattaaa aatagtcaca taatttgaat ggaaatgata taatactaaa
       61 ataaacaata taatattgta aatgcaatga aagaggaaag tattttgatt aaacttagta
      121 aagagataaa cacctaggct gggagtgttt tctaagaggt catgagaagt tccctctgga
      181 gtaacagagc tgaaatttta cagtaggctt tgacgtcaaa aacgcgttaa gtttgttaga
      241 ggtggtttga tgatttttaa attgttaaac tactagggtg gtaccgcgaa actatagcct
      301 ttcgtcccta gacagggatt gaggggcttt ttttatacaa aaaaacgaaa gggtgatatg
      361 tgtgcaagaa aaattacttg ctttacgtga agcagctttg gctgaaataa aagaagcaca
      421 aagcatagaa agtgtagaaa gtttaagagt taagtactta ggaaaaaaag gtgagataac
      481 tgccatactt aaagaaatgg gtaaattatc tgctgaagaa agaccagtag ttggtaaggt
      541 tgccaatgag gtaagagaaa acattgaact tagcataaat tctaaaaaag aagaaataaa
      601 tgctattgaa aaagaaagaa aattaaaaga ggaagtgata gatgttactc aaccaggaaa
      661 agttttaaag gttgggaaga agcatccaat aactcaaatt atagatgaag taacagatat
      721 atttatcgga atgggattct ctatagcaga agggccagaa gttgagactg ttgaaaacaa
      781 ctttgacgca ttaaacgctc ctaaagacca tccatcaaga gatatgagcg atacattcta
      841 tatcaatgat ggggtattac ttagaactca aacatctcca gttcaagtaa gaactatgag
      901 aagtcaagag ttaccaataa aagtaattgc accaggtaga tgttttaggt cagactcgcc
      961 agatgctaca cactcaccaa tgttccatca gatagaaggg cttgttgttg gaaaagatgt
     1021 tactatggca gaatttaaag gaactatgga tatcttcgtt gaaaaattgt ttggttctga
     1081 tatcaaaact aagtttagac ctcacaactt cccatttaca gaaccaagtg cagaggttga
     1141 tgttacttgt ttcaaatgtg gtggtaaagg ttgcccaatg tgtaaatatg aaggttggat
     1201 agaaatatta ggttcaggta tggttcatcc aaatgtgctt agaaattgtg gaatagaccc
     1261 agaagtttac agtggatttg catttggagt tggggttgaa agacttgcaa tgcttaaata
     1321 cgaaatagat gatattagat tattattcga aaatgatatg agattcttaa atcaatttta
     1381 attaggaggg tatgtagatg ttagtatctt taaaatggct tagagactat gttgatatag
     1441 acatggatgt aaaagagttc gctgataaaa tgacaatgac aggaactaaa gttgaaacaa
     1501 tagattatta tggtgaagaa atagaaaata tattggttgg aaagatttta gaaataaaac
     1561 aacatccaaa tgctgataag ttggttgtaa ccaaagtaga tattggagat aaagttgttc
     1621 aaatagttac aggagctaca aatatatcag aaggagatta tattccagta gctgtaaatg
     1681 gttctaagtt acctggagga gttgaaatca aacagactga tttcagaggt gaattatcag
     1741 atggtatgat gtgttcagca gctgaactag gtatagatga acattacatt gaggagtata
     1801 aaagaggtgg tatatatatt ttagaccacg aagattctta tgaattagga aaagatataa
     1861 aagatgtttt aggattaaaa gatgctttaa tagattttga attaacttca aacagacctg
     1921 attgtaaatg catgatgggt atagctagag aagcagctgc aactatagga acaaaagtaa
     1981 aatatcctga aatcgaagta aaagaaagtg acgaagagat agatttcaaa gttgagatag
     2041 ataatccaga tttatgtaga agatatgttg ctagaatggt tacagatgta aaaatagaac
     2101 cttctccata ttggatgcaa agaagactta cagaagcagg agtaagacct ataagtaaca
     2161 tagtcgatat aacaaacttc gtaatgttag agcttggtca accacttcat gcttttgata
     2221 taaatcaagt agagactgga agaatagtag taagaaatgc taaagatgga gagaaacttg
     2281 taacattaga tgatgttgag agaacattag acaaagatat gctagttata acaaatggag
     2341 aaaaatcact tggtttagct ggtgtaatgg gtggtgctaa ctcagaaata acttctaata
     2401 cgaagactgt actttttgaa agtgccaatt tcaaaccaga aaacataaga atgacagcta
     2461 aaaaagttgg tattaggtca gaagcatctt caagaaatga aaaagactta gaccctaatc
     2521 ttgcagagat agcagcaaat agagctgcac aacttgttga aatgttagga gcaggaaaag
     2581 ttttaaaagg tgttgtagat gtatatccaa ataaaccaga acctaaaaaa ttggtagtaa
     2641 atcctcaaag aattaaccac ctattaggtg tagatgtacc aatggagcag tttgtaggaa
     2701 ttttagaatc attagagttt aaatgtaatt tggtagctaa tgataaatta gaaatagatg
     2761 taccaagctt tagaacagat atggaacaag aagctgatgt atgggaagaa atagctagaa
     2821 tttatggatt tgagaatata ccttctgtac aattagaagg aaatacgaca gcaggaatta
     2881 aaacttcaaa acaaaaattc atggatgctt taaaagataa ttcaactgct gtaggattaa
     2941 atgaaatatt aacatattca tttgtaagcc ctaagggagt agataagata agagtaccag
     3001 aaggtaatgc aaagagaaat tttgttaaat tacttaaccc attaggagaa gaaacttctg
     3061 taatgagaac tactttaata ccaaatatgt tagatgtttt atcaactaat gtatctcata
     3121 aaatagaaga agtatctgca tttgagtgtg gacatatatt catcccacaa gattcagaat
     3181 tacctaagga agaaaataga atgtgtgtag gtatgtatgg taaagatgtt gacttctttg
     3241 cactaaaagg aactatagaa actatacttg taaatgtcgg atttaaaggt tatgaaattg
     3301 aacctcaaga taataatact accttccacc ctggtagatg tgctaaaata gtgtataata
     3361 ataaatatgt aggtacatta ggtgaattgc atccagatgt tatagaaaac tacaatctag
     3421 gtcaaagagt ttatgtcgct gaaatagata ttgactttgt atttgataat tctgatagaa
     3481 caaagaatta tgtgccatta ccaaaatatc catctacatc aagagatata gctcttattg
     3541 ttaaagatga tgtatttgta aaacaaatag aagatataat aaaggaaaat ggtcaaggat
     3601 tagtagaaag ctacaagtta tttgatgttt acaaaggttc tcaaatagaa gctggataca
     3661 agtcaattgc atattcaata acttatagaa gtaaagataa aactctaaca gatgaagatg
     3721 tagctaaggt gcatgataag atattaagtg aattaagcga aaaattaaat gctaacttaa
     3781 gatcaaatta acaactaatg tcggggaggt taggatgaac aaagtaatgg ttaaaatcca
     3841 tggcgctgaa tatccaatgg ttggagacaa atcagagaag tttatgatta gtattgctga
     3901 ttttgtagac aaagaaatgg ataaaataac acgtcaaaac ccgaaattga gcttatcagt
     3961 tgctgcgata ttaactgcat taaatatatc agacctttta tttgaatgtt cagatgagaa
     4021 tgagaagttg attaaagcta atgaagaatt gagtaagaag gttggagcat ctaatgaaga
     4081 gcttcaatta gaaatcaagt ctttaaagct tacgatagca gaaaaagaag cagaaaatcg
     4141 tgaagctgaa actaagatga aagagttaat tgagattata gaaaataaaa agcaagaaat
     4201 attcgaactt agtaatacga cagaaggttc tagagcagag ttagatgctt ataaaaacaa
     4261 gattgaggag ttaagtactc aacttgaaga agcaaatgaa agagctacta tagctgaaaa
     4321 cttagcttct gagtttcaaa acaaagctta tgatttacag ttaaaatgta cagggttaaa
     4381 taatgatgca aaaaatgtgg aataaactaa aagatttgct gtctcttgtt ttttgagaca
     4441 gcttctttta atgtataaat ataaatgcta tataaatata gataa
//
LOCUS       DAEORM030000126         4411 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.132, whole genome shotgun sequence.
ACCESSION   DAEORM030000126 DAEORM030000000
VERSION     DAEORM030000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4411)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4411)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 4411)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4411
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.132"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            38..706
                     /locus_tag="KRH23_003770"
     CDS             38..706
                     /locus_tag="KRH23_003770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MORN repeat-containing protein"
                     /protein_id="HHS5227033.1"
                     /translation="MENITSYFTTILCVFICLSSVFIFTQLARVFINKKKINQKIKSR
                     NGFRYDRDFIEARREEIHIKDNNNNKNKSNNKKLKEEKVFKYDNGDLYKGEFVDGKKN
                     GFGIYIFSSKEKYEGLWKDDKMHGIGKYTYRDGSIYTGEFKYGLKNGLGKLTYPNNDI
                     YKGYFLDNKKNGKGVLYKNDGNKQAGIWEDDEQCKSLDFKDLNNNKINNVYQNRLNNN
                     KLKV"
     gene            865..1371
                     /locus_tag="KRH23_003771"
     CDS             865..1371
                     /locus_tag="KRH23_003771"
                     /EC_number="3.1.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HHS5227034.1"
                     /translation="MKEYVVVDLETTGLDPYKGCEIIEIGITEIKNEQIVKNYSRLIK
                     PKGIISSFITELTHISNEMVENEEPLELVLPRFRKYIGDRTIIAHNAKFDLKFLNYYL
                     RMLDLEPINNYICTVELLKKCKSYKGKNKKLETACAYYNIENINAHRADSDTLATAKL
                     FLKIKDEY"
     gene            1499..2515
                     /locus_tag="KRH23_003772"
     CDS             1499..2515
                     /locus_tag="KRH23_003772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase domain-containing protein"
                     /protein_id="HHS5227035.1"
                     /translation="MGYYNDNDNNKIRRKKISNNKDSNKKSKHSYTSANKKNKSPNTS
                     SSKRMSEKVDSQNLIKRDRDSFTRDNVRPLNTDYNQRERRRVEYKQREKKLKSKKRKK
                     QKRIRIVRALLSIMLVALIIFSVAGAIFTVSAIKGSPEVTKKLIRSKYISSEVVSIKQ
                     MPNDLKHAIVSIEDERFYKHKGVDVISLVRSVLNNVFTDTTQGASTIDMQVSKNLLTS
                     NDKTMKRKIRDMYNAKQMNKIMTKDEILEAYLNNMYLGKNAYGAAKGAEVYFGKKVSE
                     LNLAECAMLAGMTNNPARYIDHGEAKKRQVIVLYKMHQLGYITDKEYRMAKADDTPFK
                     SEID"
     regulatory      2710..2804
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00442"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="guanidine-I (ykkC/yxkD leader) riboswitch;
                     Guanidine-I riboswitches control genes whose products are
                     involved in modification or pumping out guanidine as a
                     toxic compound from bacteria; This is class of guanidine
                     riboswitches is based on the ykkC/yxkD leader; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="guanidine"
                     /db_xref="RFAM:RF00442"
     gene            2868..3572
                     /locus_tag="KRH23_003773"
     CDS             2868..3572
                     /locus_tag="KRH23_003773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="B3/B4 domain-containing protein"
                     /protein_id="HHS5227036.1"
                     /translation="MKKFVIEDAFWNLFPSAKIGVVICNDIDNSIKDEDYKTIILKGE
                     EEALKYLEDSEFSNNQVIKVWREAFKKFKTKKGARSSIEALLKRVHNGNNIGTINPLV
                     DIYNFISLKYALPCGGEDIDKFIGDIRLTRAIGNEEFIPLGTDENSFPYEGEIIYKDD
                     GGAICRCWNWREAVRTMLTEDTNNAFLCIELVDESRFKEFENALNELAKIVQEKLGGN
                     CKISILDIDNKEISVD"
     gene            3867..4346
                     /locus_tag="KRH23_003774"
     CDS             3867..4346
                     /locus_tag="KRH23_003774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HHS5227037.1"
                     /translation="MSNKLIKNLLSGILQILFFLLGLVIVVGGFKSFMYLCFSGEATL
                     QGTIYGILMFILGVSYFIIIKSLIEVLGSSEHSLFVKENVKRFRIIGYLLLLNSLIEF
                     ISTFGTTGKGMRFLDLGFGFYFTVPVFVYFITSLMSFVIADGFVKAIKIKEDNDLTI"
BASE COUNT         1847 a          376 c          753 g         1435 t
ORIGIN      
        1 aggtatttta aataaatttt ttaaagggtg attttttatg gaaaatataa ctagttattt
       61 tacaacaata ctatgtgtat ttatatgctt atcatctgta tttatattta ctcaactagc
      121 tagagtattt attaataaga agaagattaa tcaaaaaatt aaatcaagaa acggatttag
      181 gtatgataga gattttattg aagccagaag agaagaaata catataaagg ataacaataa
      241 taataaaaat aagagtaaca ataagaaatt aaaggaagaa aaagtattta aatacgataa
      301 tggtgattta tataaaggtg agtttgttga tggaaagaaa aatggatttg gaatatatat
      361 tttttcaagt aaggaaaagt atgaaggatt atggaaagat gacaagatgc atggaatagg
      421 aaaatatact tatagagatg gttcaatata tacaggtgaa tttaaatacg gattaaaaaa
      481 tggtttggga aaattaacat atcccaataa tgacatttat aagggatatt ttttagataa
      541 taagaaaaat ggtaagggtg tattatataa aaatgatgga aataaacaag caggaatatg
      601 ggaagatgat gaacaatgta aaagtttaga ttttaaagat ttaaataata ataaaataaa
      661 taatgtttat caaaatagat taaataacaa taaattaaaa gtttaattat tctaataaaa
      721 aaatctttat ttatgatgga atataggata tatctatgtt gtaatttgta aaatcttcct
      781 atatcatata aaattaagta ttgattagtc tattacataa atatagaata taaatatatc
      841 catttaataa taaggagaag agatatgaaa gagtatgtag ttgtggattt agaaactaca
      901 ggattagatc catataaagg ttgtgaaata atagaaatag gaataacaga aataaaaaat
      961 gaacaaattg taaaaaacta ttcaaggttg ataaaaccta aggggataat ttcttcattt
     1021 ataacagaat tgacacatat aagtaatgaa atggtagaaa atgaagaacc actagaatta
     1081 gttttaccta gatttagaaa atacataggt gatagaacta taattgcaca caatgcgaaa
     1141 tttgatttaa aatttttaaa ttactatctt agaatgttag atttagaacc aataaacaat
     1201 tatatatgta cagtagagtt attaaaaaaa tgtaaaagtt ataaaggaaa aaacaagaaa
     1261 cttgaaacag cttgtgctta ttacaacata gagaatataa atgctcatag agctgacagt
     1321 gatacattag caactgcaaa actatttttg aaaataaaag atgaatatta attataaata
     1381 tagagaaaat tagtgaaaat atcctttata aaattgaccc ttaagcttac aattttgttc
     1441 tttgatttat tttgtagaac aatgtataat gtaccttata tgaagaaggg agactaaaat
     1501 gggttattac aatgataatg ataataataa aataagacgt aaaaaaatta gtaacaacaa
     1561 agatagtaat aaaaaatcta aacattctta tacttcggca aataaaaaaa ataaaagtcc
     1621 taatacaagt tccagtaaaa gaatgagtga aaaagtagat tcacagaatc ttataaaaag
     1681 agatagagat agttttacaa gagataatgt aagaccttta aatacagatt acaatcaaag
     1741 agaaagaaga agagtcgagt ataaacaaag agagaaaaaa ttaaaaagta aaaaaagaaa
     1801 aaaacaaaaa aggattagaa tagttagggc attattatct attatgttag ttgcactaat
     1861 tatattttca gtggcaggtg caatatttac agtttcagct ataaaagggt caccagaagt
     1921 tactaaaaag ttaattaggt ctaaatatat aagtagtgag gttgtaagta taaaacaaat
     1981 gccaaatgat ttaaaacatg caatagtttc catagaagat gagagatttt ataagcataa
     2041 aggagtagat gttatttctc tagttaggtc agtattaaac aatgtgttta cagatacaac
     2101 acaaggtgca agtactatag atatgcaagt ttcaaaaaac ctgcttacta gcaatgataa
     2161 aactatgaaa cggaaaataa gggatatgta taatgctaag cagatgaata agattatgac
     2221 taaggatgaa attcttgaag catatttaaa taatatgtat ctaggtaaaa atgcatatgg
     2281 agctgcaaag ggagctgaag tctacttcgg taaaaaagtt agtgaattaa atttagctga
     2341 gtgtgctatg ttagctggta tgacaaataa tcctgcaagg tatattgacc atggagaggc
     2401 taagaagaga caagtgattg tactgtataa gatgcatcag cttggttata taactgataa
     2461 ggagtataga atggcaaaag ctgatgacac tccatttaaa tcagaaattg attaaaatta
     2521 taagaatata gtatttcaat agtttaaaca aacgaaaatg taataaaaaa ggtgatttgc
     2581 cacccatttg ccaccataat tataatttaa tagcaaattg ttttaatgta caaatccgat
     2641 aatataatat tgttttaaat actacattat gctaaaattt aattgtattt tgtaaattaa
     2701 aaaacttata acttagtttt ctagggttcc gcattttata atggtcaggt ccaagaggaa
     2761 acgcacaatt gttgtgtaca cggaaggata aaagcctggg agatatttaa taatatttct
     2821 ataggctttt ttatttttac atattttaaa tttgaggagg ttttctaatg aaaaaatttg
     2881 ttattgagga tgcattttgg aatctatttc ctagtgcaaa aattggagtt gttatttgta
     2941 atgatataga taactctata aaagatgaag actataagac aataattttg aagggagaag
     3001 aagaagcatt aaaatacttg gaggactcag aatttagcaa caaccaagtg attaaagtat
     3061 ggagagaagc atttaaaaaa tttaaaacga aaaaaggagc aaggtcttct attgaagcat
     3121 tattaaaaag agttcataat ggaaataata taggaactat taacccttta gtggatatct
     3181 acaattttat ctcattaaaa tatgcattac cttgtggagg ggaggatata gataaattta
     3241 taggagatat taggctaact agagcaattg gtaatgagga gtttatccca ctagggacag
     3301 atgaaaattc atttccatat gaaggagaaa taatttataa agatgatggt ggagcaattt
     3361 gtagatgttg gaattggcgt gaagcagtga gaacaatgct tactgaagat actaacaatg
     3421 cctttttatg cattgaatta gtagatgaaa gtagatttaa agaatttgaa aatgctttaa
     3481 atgaattagc taaaatagtt caagaaaaat tgggtgggaa ttgtaaaatt tcaattttag
     3541 atattgataa taaagagata tcagtggatt aatatggagg tgctgttgta atggactatt
     3601 ctagttataa agatacttat atttaggata agaaggtcta ttttagatat aacgattatc
     3661 aaaggatata atatagaaaa taaaaatgta gaatataaaa agcttttaaa ataagaaaaa
     3721 aatgtatttt aaaggctttt attatactct tttttatttg cataattaac aataaaatta
     3781 tattgttaat tataatattt ttattgaaaa acgatataat ataatgtatt atactatata
     3841 taaaatattt taaaggagtt ggcatgatgt ctaataaact tataaaaaat ttactaagtg
     3901 gtatattaca aattttattt tttcttttag gattagtaat tgttgtggga ggatttaaaa
     3961 gttttatgta cctctgtttt agtggagaag caactctaca aggcactatt tatggaatat
     4021 taatgtttat tttaggtgta tcatatttta tcattataaa atcattgata gaagtattag
     4081 gtagttctga acatagccta tttgtaaaag agaatgtaaa aagatttagg attattggat
     4141 atcttttgct tttaaactct ctaattgagt ttatttcaac ttttggtact actggaaaag
     4201 gaatgagatt tctagattta ggatttggat tttattttac tgttccagta tttgtatatt
     4261 ttataacttc tcttatgagt tttgtaattg cagatggatt tgtaaaggca ataaagataa
     4321 aagaggataa tgatttaact atttaggtgt gacactttaa tatataggag ataaataacc
     4381 cgaaaagagt gattaactag taatttaaaa t
//
LOCUS       DAEORM030000127         4302 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.133, whole genome shotgun sequence.
ACCESSION   DAEORM030000127 DAEORM030000000
VERSION     DAEORM030000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4302)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4302)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 4302)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4302
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.133"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            359..2458
                     /gene="nrdE"
                     /locus_tag="KRH23_003775"
     CDS             359..2458
                     /gene="nrdE"
                     /locus_tag="KRH23_003775"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HHS5227038.1"
                     /translation="MNWIELNNQVIIKNEQGKYQLEKDKEALSSYIEEFIQPKLRKFN
                     NLEERLKYLIDEGYYSKEVINQYSIDVIKNIYDMIDKHKFEFQSYMSANKFYQNYALK
                     SNDGKEILETYNDKVLIVALTLGNGNKDLALNLADKIVKQEFQPATPTFLNAGRKRAG
                     EMVSCFLLSVEDSTEGISYAISSSNHLSKIGGGVALNLSKLRASGESIKDIEGAAGGV
                     VGVAKMLEQSFSYFNQMGARQGSGAVYLTVFHPDFELLMDTKKINADEKIRLATLSLG
                     AIIPDKFMELAEKNEVAYAFYPHTVYKKYGVSLDEIEMDEWYDKLVNDSDIRKKEINP
                     RQMLTKIAQMQQESGYPYVVYIDTANREHTLKDVGIIKMSNLCCEIFQYQTPSEIEGY
                     GGKNEWGQDISCNLGSLNIANVMDNKTIESTVETAIRALSFVADSTDIKPVPTVSNSN
                     SKSHSIGLGAMNLHGYLVRENILYTSDDAIDFSNVFFAMVRYYSIKASMKIAIERNQT
                     FEGFDKSEYVKGRNSKVLSKYYEQSYLPKSEKVRALFEGIYIPTKEDWTKLLDEVKEK
                     GIYNAYLMAVAPTQSISYVQNATSSIMPITEPVEVRTYGDSTTIYPMPFLTNDNMLYY
                     QSAYRMDMRKVIDLVATVQNHVDQGISTTLFVTDEKTTRDIARHYIYAYKKGLKSLYY
                     TRTKMTRDTHECLVCSV"
     gene            2471..3442
                     /gene="nrdF"
                     /locus_tag="KRH23_003776"
     CDS             2471..3442
                     /gene="nrdF"
                     /locus_tag="KRH23_003776"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA];
                     GO_function: GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA];
                     GO_process: GO:0009263 - deoxyribonucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HHS5227039.1"
                     /translation="MTFNLHKIHNAVNWNREEDGFTQAFWEQNVKQFWLPEEISVSKD
                     IKVWNELSNKEKELYKKVLGGLTLLDTKQGNNGIPSMMSLTENLQRKAVLSFMGTMEE
                     IHAKSYSSIFMTLLSNLEIDELFEWIETEPTLQRKADLVLAQYENTTNQEGLYLSMVT
                     SVFLESFLFYSGFFYPLYLSGQGKMVASGEIISLILRDESLHGKYIGLLAQEIYDSFD
                     KMDKEMLEEKMYSILYSLMENEIEYTNVIYRESGLEKEVVNFLKYNANRALENLGFEK
                     LYTVDAINPIVLNGLSTETKTHDFFSTKGNGYQKGVYEELEDEDFII"
     gene            3518..4144
                     /locus_tag="KRH23_003777"
     CDS             3518..4144
                     /locus_tag="KRH23_003777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HHS5227040.1"
                     /translation="MKYEWRKRDKELYLPKKNPVIVEIPEQKFIMLKGSGDPNSKEFT
                     EAIGVLYSLAYAIKTMPKKGIVPEGYFDYTVFPLEGIWDKGEKSKGLDVLIKEDLIYT
                     IMIRQPDFVTQDLLDKATDIVKKKKPHNLLEKVRFGSINEGLCVQMLHIGSYDNEPES
                     FDIMNEFCKKNKLIRKSYTHREIYISDARKVSPESLKTVLRFEVEREV"
BASE COUNT         1722 a          461 c          788 g         1331 t
ORIGIN      
        1 ttttttcaat atatcagaat atattttcaa gctatttaga gataatttaa atttttaaac
       61 aggacataat aagcttgtat tgttttatat ttgagttgat aaaaatttct ttaaataaaa
      121 ataatgtcaa ttataaagta ataaaagttt agatataaaa aaatttgtgt atatactata
      181 tgtagtatat aatagataaa gcactgacta tatgtagtgc ttttgttttt gaaaaatact
      241 tattgcattt ctataattat agattaattt tgggatttca actgataagt accaaaagaa
      301 ataataagca aattaagtga aattatggca caagattatg ttaaaaggac ggtaaataat
      361 gaattggata gagcttaaca atcaagtgat aattaaaaat gaacaaggca agtaccaatt
      421 ggaaaaggat aaggaagcct taagtagtta catagaagaa tttatacagc caaagttgag
      481 aaaatttaat aacctagaag aaagattgaa gtatttaata gatgaaggtt attattcaaa
      541 agaagtaata aatcagtata gcatagatgt tattaaaaat atatatgata tgattgataa
      601 acataagttt gaatttcaat catatatgag tgcaaataag ttttatcaaa attatgcatt
      661 aaagagcaat gatggaaagg aaatattaga aacatataat gataaagtgt taattgtagc
      721 tttgacacta ggaaatggca ataaagattt agctttaaac ttggcagata aaatagtaaa
      781 acaagaattt caaccagcta cacctacttt tttaaatgct ggaagaaaaa gggctggaga
      841 aatggtatca tgttttttac tatctgtaga agatagtaca gaaggtatat cgtatgctat
      901 atcttcatca aatcacttat caaagattgg tggaggagtt gcactaaatt tatctaaact
      961 tagagcatct ggcgaatcta tcaaagatat agaaggtgca gctggaggtg ttgttggagt
     1021 agctaaaatg ttagaacaat catttagtta ctttaatcaa atgggagcta gacaaggttc
     1081 tggtgcggtg taccttactg tattccatcc tgattttgaa ttgttgatgg atactaaaaa
     1141 gataaatgca gatgaaaaaa taaggcttgc tacattatca ttaggagcta taataccaga
     1201 taaatttatg gagttggcag aaaaaaatga agtagcatat gcattttatc ctcatactgt
     1261 gtataagaaa tatggagttt ctcttgatga gatagaaatg gatgagtggt atgataaatt
     1321 ggttaatgat agtgatataa gaaaaaaaga aataaatcct aggcagatgt tgacaaaaat
     1381 agcacagatg caacaagaaa gtggatatcc atatgtagtg tacatagata cagctaatag
     1441 agaacataca ttaaaagatg ttggaattat taaaatgtct aacttatgtt gtgagatatt
     1501 tcaatatcaa acaccttcag aaatagaggg gtatggagga aaaaatgaat ggggacaaga
     1561 tataagttgt aacctaggtt ctttaaacat agccaatgta atggataata aaactataga
     1621 aagtacagtt gaaacagcaa taagagcact gtcatttgta gcagatagca cagatataaa
     1681 accagtgcca acggtaagca atagtaacag caagtctcat tctataggat taggagctat
     1741 gaatttacat ggatacttag taagagaaaa tattttatat acttcagatg atgctataga
     1801 tttttctaat gtattttttg caatggttag atactattca attaaagctt ctatgaaaat
     1861 agccatagaa agaaatcaaa cttttgaagg atttgataaa tcagaatatg ttaagggaag
     1921 aaatagcaag gttttatcaa aatactatga acaatcttat ctacctaagt cagaaaaggt
     1981 aagagcatta tttgaaggga tttatatacc aacaaaagaa gactggacaa aattattgga
     2041 tgaagtaaaa gaaaaaggga tatataatgc atatttaatg gcagtagcac caactcaaag
     2101 cattagttat gttcaaaatg ctacatcaag tataatgcca attactgagc cagtagaagt
     2161 aagaacatat ggagactcta ctacaatata tccaatgcca tttttaacaa atgataatat
     2221 gttgtattat caatcagcat acaggatgga tatgagaaag gtcatagatt tagtggcaac
     2281 agttcaaaac catgttgacc aaggtatatc aacaacactg tttgttacag atgaaaagac
     2341 aactagagat atagctagac attacatata tgcctataaa aaaggtttga aaagtttata
     2401 ttacacaaga acaaagatga caagagatac tcatgagtgt ctagtgtgtt cagtataggg
     2461 agagaaatat atgacattta atttacataa aatacataat gcagttaact ggaatagaga
     2521 agaagatgga tttacacaag ctttttggga acaaaatgta aaacaatttt ggcttcctga
     2581 agaaatatct gtttctaaag acataaaggt atggaatgaa ctaagtaata aagaaaagga
     2641 attatataaa aaagtattgg gtggtttaac attactggat acaaaacagg ggaataatgg
     2701 aataccatct atgatgagtt taacagaaaa cctacaaaga aaagctgtct tgtcttttat
     2761 ggggactatg gaagaaatac atgcaaaaag ttattcttct atatttatga ctctactttc
     2821 taatttagaa atagatgaat tatttgaatg gatagaaaca gaaccaacat tacaaagaaa
     2881 ggctgattta gttttagctc aatacgaaaa tactacaaat caagagggat tatacctatc
     2941 aatggttaca agtgtatttt tagagagttt cttgttttat tcaggattct tttatccatt
     3001 gtatctatct ggtcaaggaa agatggtagc tagtggagaa ataatatcgc ttattcttag
     3061 agatgagtct ttacatggta agtatatagg attgctagca caagaaatat acgattcatt
     3121 tgataaaatg gataaggaga tgttagaaga gaagatgtat tctatacttt atagccttat
     3181 ggagaatgag atagagtata caaatgttat atacagagaa agtgggcttg aaaaagaggt
     3241 tgtgaacttt ttaaaataca atgcgaatag agctttagaa aatctagggt ttgagaagct
     3301 atatactgta gatgctataa atccaattgt attaaatggt cttagcactg aaaccaaaac
     3361 acatgatttt ttttcaacta agggtaatgg ataccaaaaa ggagtgtatg aggaattaga
     3421 ggatgaagat tttataatat aatttataat tatgacacac tgttgtcact tttagcgtga
     3481 taatatcaat gtataaaata tatatggagg tatttttatg aaatatgaat ggagaaaaag
     3541 agataaagag ttatatttac ctaaaaagaa tcctgtaata gttgaaatac cagaacagaa
     3601 atttatcatg ttaaaaggga gtggagaccc aaattctaaa gaatttactg aagcaatagg
     3661 agtactttat tctttggcat atgcaataaa aaccatgcct aaaaaaggaa ttgtaccaga
     3721 agggtatttt gactatacgg tttttccttt agaaggtata tgggataagg gagaaaaaag
     3781 taaaggctta gatgtactta ttaaagaaga tttaatttac actataatga tacgtcagcc
     3841 agattttgtt acacaagacc tgttggataa agctactgat atagtaaaga agaaaaaacc
     3901 tcataatctt cttgaaaaag ttagatttgg gtctattaat gaagggctat gtgttcaaat
     3961 gcttcatata ggttcatatg ataatgaacc agaaagcttt gacattatga acgaattttg
     4021 caaaaaaaat aaacttataa gaaaatctta cacacatcgt gaaatttata taagtgatgc
     4081 tagaaaagta tcgcctgaat cattgaagac ggttttacgt tttgaagtag aaagggaagt
     4141 ataaatattt tgaataattt ataagagtta taaaaagtga agtctgttga gacttcattt
     4201 tttgatgcaa ttttaaaatt aaatttgatg tttcataata ttttaaaaac tttctacttt
     4261 tattagtgtg aataactgtt gctattaaat aataatacta at
//
LOCUS       DAEORM030000128         4058 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.134, whole genome shotgun sequence.
ACCESSION   DAEORM030000128 DAEORM030000000
VERSION     DAEORM030000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4058)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4058)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 4058)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4058
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.134"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            complement(289..1539)
                     /locus_tag="KRH23_003778"
     CDS             complement(289..1539)
                     /locus_tag="KRH23_003778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1015 domain-containing protein"
                     /protein_id="HHS5227041.1"
                     /translation="MATIKPFKAIRPNKYIVDKVAALPYDVMNSKEARRIAEGNPYSF
                     LHIDKSEIDLDENIDLYDEKVYLKARENLDEFRKQEILVKDDKECIYIYKQIMDGRAQ
                     VGIVACISVDESLNGTIKKHEYTRPEKEIDRTKHIKYCDANTGTILVTYKHQRVIDDI
                     INDFMDNNEPLYDFITDDKIEHTVWKIDNDDIIDNLVDKFEKLDYLYIADGHHRTASA
                     ENVAKEMRAKNPNYTGKEEFNYFIAMIAPDENLMVLDYNRVIKDLNGLSEEEFINKIK
                     ENFELEEIEGKEKYKPDKKGTFGMYLGDKWYKMKANKNLLEIEDPVDSLDISILQDYV
                     IDAILGIDNPRVDKRIDFIGGIRGLEELEKRVNEDMKVAFAMYPTSIEDLIRVADANK
                     IMPAKSTWFEPKVRCGLFLHEINE"
     gene            complement(1571..2512)
                     /locus_tag="KRH23_003779"
     CDS             complement(1571..2512)
                     /locus_tag="KRH23_003779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-2-hydroxyacid dehydrogenase"
                     /protein_id="HHS5227042.1"
                     /translation="MYNILVTDGIEKEAARKLRELDFNVIEQFYEKDVLGDKLKDVDV
                     LVVRSATKVTKDVIDKALEGKKLKLIVRGGVGLDNIDVKYAQANGIKVMNTPNASSIS
                     VAELTIGQLFVLARFINTANVTMRDGKWEKKKYKGTEINGKTLGLIGFGRIAKEVAKR
                     AELLGMNVIYTDIMGEAQGFNNYKFCDMEEVLENADFLSLHIPFDKNKGAVITEKEIN
                     KMKKGAYLINCARGGLVDEKDLLKALDEGKLSAAAIDVYEQEPTLNLDLVNHPRVSPT
                     PHIGASTVEAQERIGDEIVNVIQDFFLDFNNLIGVAL"
     gene            complement(2752..3828)
                     /locus_tag="KRH23_003780"
     CDS             complement(2752..3828)
                     /locus_tag="KRH23_003780"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal-phosphate-dependent aminotransferase
                     family protein"
                     /protein_id="HHS5227043.1"
                     /translation="MSKKLFIPGPIDVKEEVLQKMATPMIGHRGKDASMLQKSISEKM
                     QKLFYTNNTILLSTSSGTGLMEGSIRSCTSKKAAVFSCGSFGDRWYKMAVANNVPADI
                     FKVELGEATTPEMVDKVLSTGEYDLITVTHNETSTGIRNPIEEIGEVVKKYEDVIYCV
                     DTVSSAGGIKVEVDKIGIDICITSVQKALGLPPGMSICTFSQKAIDRAKQVPFRGVYL
                     DLLAMYEYLIKKNYQYPSTPSLSHMFALDFQLDNILDEGLDNRFNRHEDMANLVRNWA
                     KKHFQIFTNENHLSNTLTVIENTQGISVSNLNSKLQERGFQIANGYGDLKEKTFRISH
                     MGDYTVEDVQELLDNIDDILGFNK"
BASE COUNT         1232 a          732 c          422 g         1672 t
ORIGIN      
        1 aaaatcactt tttttattaa cttttttata attataataa aaatatataa cagtactatt
       61 ataaatacac atttaaaacc ttataaatat acaaatacaa ttatatgaat tttcatcctc
      121 aattatagca tagaatatga ctatctatat cctaaaatta tccatttcta aaaaaaaggt
      181 aactattatt aagaatatca acttatagaa tttatattcc acatacgatt ttcaatcaaa
      241 aaaacaaggg ctaaaaagtg aattgtgcac tttttagccc tttattaatt attcatttat
      301 ttcatgtaag aatagaccac atcttacttt aggttcaaac catgttgact tagctggcat
      361 tatcttattt gcatctgcta ctcttattaa atcttcaata ctagtaggat acattgcaaa
      421 tgctactttc atatcttcat taactctttt ttctaattct tcaagacctc taattccacc
      481 gataaaatca attcttttat ctactctagg attatcaatt cctaaaatag catcaataac
      541 atagtcttgt aatatagaaa tgtctaatga gtcaacaggg tcttctattt ctaataaatt
      601 tttatttgct ttcattttat accacttatc acctaggtac attccgaaag ttcctttttt
      661 gtcaggttta tatttttctt ttccttctat ttcttctagt tcaaaatttt cttttatttt
      721 atttataaat tcttcctcgc ttaaaccatt taagtctttg ataaccctat tataatccaa
      781 aaccattaaa ttctcatctg gtgcaatcat tgctatgaag taattaaatt cttcttttcc
      841 agtataattt ggatttttag ctctcatttc tttggctaca ttttctgctg aagctgtcct
      901 atgatgacca tctgcaatgt atagataatc taatttttca aatttatcta ctaggttatc
      961 tattatatca tcattatcaa tcttccatac tgtatgctct atcttgtcat ctgttatgaa
     1021 atcatataaa ggttcattat tatccataaa atcattgatt atatcatcta tcaccctttg
     1081 atgtttgtaa gttacaagta tagttcccgt attagcatca cagtatttta tgtgtttagt
     1141 tctatcaatt tccttttctg gtcgagtgta ctcatgtttt tttattgttc cattcaagct
     1201 ttcatcaact gatatacatg ctactatacc aacttgagct ctaccatcca tgatttgttt
     1261 atatatatat atacactctt tgtcatcttt tactagaatt tcttgttttc gaaactcatc
     1321 taaattttct cgcgctttta aataaacttt ttcatcatat aaatctatat tttcatctaa
     1381 atcaatttct gatttatcta tatgcaaaaa tgaatatgga ttcccttctg caattcttct
     1441 agcttcttta ctattcataa catcgtaagg aagtgctgct actttatcta ctatatattt
     1501 atttggtcta atcgccttaa atggtttaat cgttgccatt actaatttcc tcctaattat
     1561 acaaaatatt ttataatgct acccctatta gattgttgaa gtcaagaaag aaatcttgaa
     1621 tcacatttac tatttcgtct cctattcttt cttgagcttc tactgtagat gccccaatat
     1681 gaggtgtagg agaaactctt ggatgattta ctaagtctaa atttaatgta ggttcttgtt
     1741 cataaacatc tatagcagct gctgataatt taccttcatc taatgctttt agtaaatctt
     1801 tttcatcaac taaaccgcct cttgcacagt ttattaaata agcccctttc ttcatcttat
     1861 ttatttcttt ttcagttatt actgccccct tattcttatc aaatggtatg tgtaaagata
     1921 agaaatctgc attttctaaa acttcttcca tatcacagaa tttataattg ttaaagcctt
     1981 gcgcctcacc cattatgtca gtatatataa cattcatacc taataattct gctctctttg
     2041 caacttcttt tgcaattctt ccaaaaccta taagtccaag tgtctttcca ttaatttctg
     2101 tacctttata ctttttcttc tcccattttc catctctcat agttacattt gcagtattta
     2161 tgaatcttgc aagaacaaat aattgaccta ttgtaagctc tgcaacagat atactgcttg
     2221 catttggagt attcataact tttatgccat tagcttgagc atatttaaca tctatattat
     2281 ccagacctac tccacctctt actatcaact tcaacttttt accctctaat gctttatcta
     2341 ttacatcttt agtaacttta gtagctgaac gtactacaag tacatcaaca tctttaagtt
     2401 tatctcctaa aacatctttt tcataaaact gctctatcac attaaaatct aactctctca
     2461 attttctcgc tgcttctttc tctattccat cagtaactaa tatattatac ataacaaact
     2521 cctccaattt ttattcactt aatttttcca atttttattt tttaaagtat tttcatcaat
     2581 aaaaaacttt acttaattca actttctgtt tatataattt tcaaaatatt tttttattaa
     2641 agtcatatca aatttttcta ttgtttgtta aaaatttaat atgtaatttt tataaaatat
     2701 tatttattat atattctaaa tttatcttaa aacatacata tttttacaat attatttatt
     2761 aaaacctaat atatcatcaa tattatctaa taattcttgt acatcttcga cagtatagtc
     2821 acccatatgt gaaattctaa aagttttttc ttttaaatct ccatagccat ttgctatttg
     2881 gaatcctcgt tcttgtaatt ttgaatttaa atttgataca ctaatacctt gagtattttc
     2941 tataacagta agtgtattgg ataagtgatt ttcattggta aaaatttgga agtgtttttt
     3001 agcccagttt ctaactaagt ttgccatgtc ttcatgtctg ttgaatctgt tatctaggcc
     3061 ttcatctaat atattatcta attggaaatc taaagcgaac atgtgagaaa gagatggtgt
     3121 tgaagggtat tggtagtttt tcttgattaa gtattcatac attgctaaca aatcaagata
     3181 tactcctcta aaaggtactt gcttagctct atcgattgct ttttgagaaa atgtgcaaat
     3241 agacattcct ggtggtaatc ccagtgcttt ttgtactgat gttatacaaa tatctattcc
     3301 aatcttatca acctcgactt ttattccacc ggctgaactt acagtatcta cacagtagat
     3361 tacatcttca tactttttaa caacttctcc aatttcttct attggatttc ttattccagt
     3421 tgaagtttca ttgtgagtta cagttattaa atcgtattct ccggtagaaa gtaccttatc
     3481 aaccatttct ggcgttgttg cctctcctaa ttcaacttta aatatatccg ctgggacatt
     3541 attagccact gccattttgt accatctatc accaaaggat ccacaggaaa atactgctgc
     3601 ctttttggat gtacaggaac gaatggagcc ttccattaaa ccagttccgg atgacgtgga
     3661 taaaagtatc gtgttgtttg tatagaatag tttttgcatc ttttcactta tactcttttg
     3721 gagcatagat gcatcttttc ctctatgtcc tatcattggt gtagccatct tttgcaagac
     3781 ttcttcttta acatcaatag gaccaggaat aaataatttc ttactcatta taattccccc
     3841 ctttttagtt tgtaatatgg atagcgtttt tactgtcctt atttttaata actataatat
     3901 caagctgaat taactatgtc aacataaaat ttatttttta tatataattt attttatata
     3961 ttttatgaaa acattcattt tctacctttt cataagtctg aattttctga attattctct
     4021 caaaaaaaat atacttttta tctatataaa ttaatttt
//
LOCUS       DAEORM030000129         4006 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.135, whole genome shotgun sequence.
ACCESSION   DAEORM030000129 DAEORM030000000
VERSION     DAEORM030000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4006)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4006)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 4006)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4006
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.135"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            complement(188..1480)
                     /gene="brnQ"
                     /locus_tag="KRH23_003781"
     CDS             complement(188..1480)
                     /gene="brnQ"
                     /locus_tag="KRH23_003781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015658 - branched-chain amino acid
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015803 - branched-chain amino acid
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HHS5227044.1"
                     /translation="MGEKQINFKDVIVIGFALFAMFFGAGNLIFPPYLGVLSGSSWLV
                     AFIGFLFADGGLALLAVIAATKFNGDTSKMFSRAGKGLSIALGCAMVICIGPLLAIPR
                     TAATTYEMGILPTIGSGISPVIFSIVFFALVLVLTIRPSKVVDIVGSILTPALLIALA
                     VLIVKGIVSPLGEIRDSSLIQNVFAEGITQGYQTMDALAASVFASIIIMSVIAKGYTG
                     EKEKMKATISAGVIAVIGMALVYGGLCYLGATVSQQYGQDVQQTALIVAITAALLGTT
                     GKILLAIIVALACLTTAIGLSSAAGQYFSTLTDGKLKYEHIVIVVCVFSAIISNFGVS
                     TIIQFSSPILSMVYPATITLVILALFSNKIKNDNVFKCAAYMALLVSVLTVATSFGIK
                     IPLVNSLPFASLGFNWIVPVVIAGIIGNFIPSKSSKTA"
     gene            complement(2599..3891)
                     /gene="brnQ"
                     /locus_tag="KRH23_003782"
     CDS             complement(2599..3891)
                     /gene="brnQ"
                     /locus_tag="KRH23_003782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015658 - branched-chain amino acid
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015803 - branched-chain amino acid
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HHS5227045.1"
                     /translation="MGKTKDVIVFGFALFAMFFGAGNLIFPPYLGIITGPEWLIAFLG
                     FTFADAGLALLAVMATAKFDGNVVEMFKRCGMKLGILIGCADILCIGPFLAIPRTGAT
                     TYEMGIMPLFGTSIPVLLFCILFFALSYVLTIRPSKVVDIVGQFLTPALLIALAFIII
                     KGIISPLGDIVDKPMIPNVFAEGIGQGYQTMDAFAAIALASVLIVSLNDKGYSTISDK
                     LKMIGKAGVLACGGLALVYGGLCFLGATVSTMYGTDAVQSQVIVNITEGLLGNVGKAI
                     LAVVVSLACLTTSIGLTSATGQYFSRLTKGKLSYEKIVLAVSVFSAVVASFGVGTIIK
                     IASPILSIVYPPSIVLIILAFFNEKIKNDNVYKGAVYMSLLVSILTVISSYGVAVPVV
                     NSLPLNSLGFNWVVPVIIAGIIGNFIPSKSQSNTLGTN"
BASE COUNT         1388 a          677 c          444 g         1497 t
ORIGIN      
        1 ataaatgaat cttttttatt ttattatctt tataaatcat actactccaa aaataaattt
       61 ttaaatttat caaataggat taataatgtt cttttatcta caataattta ataattcttt
      121 taaatataaa aaggaattgc ctatataatt taaaggcaat tccataatta tcaattagtt
      181 tttattatta tgcagtttta ctgcttttag atggaataaa gtttcctatt attcctgcta
      241 ttacaactgg aactatccag ttaaatccta atgaagcaaa tggtaagcta ttaactagag
      301 gaatttttat accaaaactt gttgcaactg ttaatacact tactaataat gccatgtatg
      361 cagcacattt gaacacgttg tcatttttaa ttttattact aaataatgct agtataacta
      421 gagttatagt tgctggatat accatactta gtataggaga agagaattgt attattgtac
      481 ttactccaaa gtttgatatg attgcactaa atacacaaac tactataact atatgctcat
      541 actttaattt tccatctgta agtgttgaga aatattgacc agctgctgaa gaaagaccta
      601 tagctgttgt taaacatgct aatgcaacta taatagccaa taaaatttta cctgtagttc
      661 caagtaaagc tgctgttatt gcaactatta aagctgtttg ttgaacatct tgtccatatt
      721 gttgagacac agttgctcca agataacata atccaccata aactaatgcc attcctatta
      781 ctgcaattac acctgcactt attgtggctt tcatcttttc tttctcacct gtataacctt
      841 tagctattac tgacatgatt ataattgatg caaatacact agctgccaat gcatccattg
      901 tttgataacc ttgagttata ccttctgcaa atacattttg tattaaagaa ctgtctctta
      961 tttctcctaa tggagatacg atacctttaa ctattaatac tgccaaagct ataagtaaag
     1021 ctggagttaa tattgaccca actatatcta caacttttga tggtcttatt gttaaaacca
     1081 atactagagc aaagaatact atagagaata ttactgggct tattccagaa cctattgtag
     1141 gtaatatacc catttcataa gttgttgctg ctgttctagg tattgctaaa agtggcccta
     1201 tacagattac cattgcacat cctaatgcaa tacttaatcc tttgcctgct cttgagaaca
     1261 tcttcgatgt gtctccattg aacttagttg ctgctataac tgctaataat gccaaaccac
     1321 catctgcaaa aaggaatcct atgaaagcta ctagccaact acttccagat aaaactccta
     1381 gatatggagg gaagattaag ttccctgcac caaaaaacat tgcaaatagt gcaaatccaa
     1441 ttacaattac atctttaaaa ttgatttgtt tctcacccat ttaaagcacc cccatttgaa
     1501 ttttactacc ttttactaaa aaataagtcc aatctcttaa ttaaatgaaa accttttgac
     1561 gagattttat ttaattatac atttttgact taaatttgtc aattatgttt cataatttat
     1621 aaaatcttca caatatttaa tacaactttc ttaattaaac aaaatcaacc tgtatacttt
     1681 aaacatagtt ggttttttgt tttttctcta atttttcttg ataaaattaa ctattccgaa
     1741 taattaaaat attaagactt tttagattat tcgatttatt attaagttgt attgctttat
     1801 atactgtata tatcactctc cttttttaca ttcatataat ctttttaatt caatttaaat
     1861 tttaaatatt ttgtgtttat tatataatct gaaaaaaaag cagtcaatag catttttaat
     1921 ttttttaatt ttcaaaatta tgattcttaa aaaatcgttt tccttttatc ataacaccta
     1981 tttacgttaa ttcttgtagt attttgtatt tattttgcta aattgacagt taactttatt
     2041 cattttttat tctacttacg tagatttacc tcttgttttt tactcttaaa accatttttt
     2101 ctgaaaattc cttattatga tttatcaact tatttttctt cataacaatt actctctaac
     2161 ttccaactta cttaaacttt gcagttgcta gtattcacgt ttacatactt atatgtcata
     2221 attaactaaa aattcttaat atatctctca atgaaaacaa tttactcatt tatttaatac
     2281 atttatataa tcatatgtct taaattttgt tttattattt tattattgtc acaattttat
     2341 ttatattata tttttgtaaa aatcatttaa tatgtatact taaatttata aaattactct
     2401 aaaattcttt tttaatctct attattgtta aaaaataaac catatatttt tttgatattt
     2461 tcttatactt tttccatatt aaatacaaat aattaaatat agaatctaaa aataaaagga
     2521 gttatttgta caaataactc cttttacttt tagttaactc atttatttac aattgattat
     2581 attttaatta aacaaaactt agtttgttcc aagtgtatta gattgactct ttgatggtat
     2641 aaaattacca attattccag ctattataac tggcaccacc cagttaaatc ctaatgaatt
     2701 aagaggtaaa gaatttacta ctggaacagc tactccataa ctagatataa ctgttagtat
     2761 acttacaagc aatgacatat atactgctcc tttgtataca ttatcattct taattttttc
     2821 attgaagaaa gctaaaatta ttaaaacaat tgatggtgga taaactatac ttagtatagg
     2881 agatgctatc tttattatag ttccaacacc aaaagatgct actactgcac tgaatacaga
     2941 tacagctaat actatttttt cataactcaa tttacctttt gtaagtctag agaaatattg
     3001 acctgtggca gatgtaagac ctatagatgt agttaaacat gctaatgata ctactactgc
     3061 taaaatcgct ttcccaacat ttccaagcaa tccttcagtt atatttacta ttacttgtga
     3121 ttgtactgca tctgttccat acattgttga tacagttgcc ccaaggaaac ataatcctcc
     3181 ataaactaga gctaatcctc cacaagcaag aacacccgcc ttaccaatca ttttcaactt
     3241 gtcactaata gtagaatatc ctttatcatt taaagatact attagcactg atgcaagtgc
     3301 tattgctgca aaagcatcca ttgtctgata tccttgacct ataccttctg caaatacatt
     3361 aggtatcata ggtttatcta ctatatctcc aagaggtgat ataatccctt ttataattat
     3421 aaatgctaaa gctattaaaa gagctggagt taaaaactgt ccaactatat ctacgacctt
     3481 agaaggtctt attgttagta catatgaaag cgcaaaaaaa agtatacaga ataataacac
     3541 tggaattgaa gttccaaata aaggcattat acccatttca taagttgttg cacctgttct
     3601 tggtatagct aagaatgggc ctatacataa aatatctgca caacctataa gaatccctaa
     3661 cttcatacca catcttttaa acatttcaac tacgtttcca tcgaatttag ctgtagccat
     3721 tactgctaga agtgccaatc cagcatcagc aaacgtaaat cctaagaagg caattaacca
     3781 ttctggacct gtaattattc ccaagtaagg tggaaatatt aagttacctg ctccaaagaa
     3841 cattgcaaat aacgcaaatc caaatactat aacatccttg gtcttaccca ttataaaatc
     3901 ccccttttta accttattaa attaataaaa tgtctcgatt gtttacgctt gcataagtaa
     3961 gttgaattaa acaataagaa cttattatta aattaataaa attaaa
//
LOCUS       DAEORM030000130         3562 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.136, whole genome shotgun sequence.
ACCESSION   DAEORM030000130 DAEORM030000000
VERSION     DAEORM030000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3562)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3562)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 3562)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3562
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.136"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            complement(<1..821)
                     /locus_tag="KRH23_003783"
     CDS             complement(<1..821)
                     /locus_tag="KRH23_003783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHS5227046.1"
                     /translation="MSGIISVMTQSLILSIMALGVYITYKILDFPDMSADGSYTMGAS
                     IVAFSLTNGISPVVATLMAILCGCTAGLVTGILHIKFKISNLLSGILVMGMLYSINLR
                     IMGKSNIPLFSFKHLFNGEISPIVLALAFVFICKVLLDLFLKTGLGYTLKGVGDNSQM
                     IKSLGINIGSIKILGLMISNGLIALSGSLMAQFLGFSDVNMGIGTLVLGIASIIIGIT
                     LFKKFTFIKDTTAIIVGSFIYQFTIYFAMSLGMLSTDLKLITAIVIIAFLATGNL"
     gene            complement(1627..2664)
                     /locus_tag="KRH23_003784"
     CDS             complement(1627..2664)
                     /locus_tag="KRH23_003784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HHS5227047.1"
                     /translation="MIKSKKILSLIIAGVLGVSMLTGCSQNDGSNASNENKETDSKKQ
                     KNIGISQLVEHPSLDKAKKGFIKALEDKGYKDGDNIKIDFQNAQNDMPTTQSIASKFV
                     SDKKDLIYAISTPSAQAAYNATKDIPIIMTAVTDPVEAGLVKSLEKPGGNVSGTSDYL
                     SIDKTLELVKTLTPKAKKIGVIYNTSEVNSKIQVDSLHDYAKKNNYEVVEKGISSSSE
                     VNQAISSLVGKIDVLYVPTDNLIVSSMPIVSKVANENKIPIIASEEGSVSSGALACCG
                     IDYEKLGYKAGELAIEVLEGKSVGDIPVTTLDETEIIINEDTLKALDMQKLSADNIKY
                     IKSDENAKSAK"
     gene            complement(2761..3516)
                     /locus_tag="KRH23_003785"
     CDS             complement(2761..3516)
                     /locus_tag="KRH23_003785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHS5227048.1"
                     /translation="MLQIKNLSKSFPNPYGEPNTIFENLSIDIEDGEFVSIIGSNGTG
                     KSTLLNIISGLIKESSGQITLDSTTITNLAEYKRTQIVSRVFQDPSLGTCPSMTVREN
                     LSLALNKGKLLNLKKCLRHKTNDLEHLLEGISLDLKKYLDIKVQYLSGGQRQSLSLIM
                     SSLASPKVLLLDEHTAALDPKTSNEVIELTDKIVREKNITTLMVTHNLKHALQYGDRL
                     IMLHKGEVVLDVKDKEKEDLTVEEILEKFEYAV"
BASE COUNT         1222 a          549 c          467 g         1324 t
ORIGIN      
        1 tttaagttac cagtagctag gaaagctatt ataactatgg cagttattag ttttaagtca
       61 gttgataaca ttcctaaact cattgcaaag tatatagtga attggtatat aaaagagcca
      121 acaattattg cagtagtatc tttgataaaa gtaaatttct taaatagtgt aataccaatt
      181 atgatagagg caattccaag aactaaagtt cctataccca tatttacatc tgagaatccc
      241 aagaactgag ccataagact accagataaa gctataagtc catttgaaat cataagtcct
      301 agtattttta tagaacctat atttatacct agggatttaa tcatttgaga attatcacca
      361 acacctttta aagtgtatcc aagacctgtt tttaggaata aatctaaaag gactttacag
      421 atgaatacaa aagctaaggc taaaactata ggagatattt ccccattgaa taagtgttta
      481 aagctaaata gaggaatatt tgattttccc attattctta aattgataga gtatagcatt
      541 cccataacta aaataccaga aagtaagtta gatatcttaa acttaatgtg aagaatccct
      601 gtaacaagac cagcagtaca accacataag atagccatta aagttgctac tacaggagaa
      661 ataccattag taagagaaaa tgctacaata gaagcaccca ttgtgtagct accatcagca
      721 gacatatctg gaaaatctaa gattttgtaa gttatataaa cccccagtgc cataatcgat
      781 aaaattaaac tttgcgtcat tacagatata atacctgaca taaataaaac actcctttga
      841 aaatattttt ataattttaa ttatttgcta attttgtgta taaaaaaacc acatagtgta
      901 caaaactatg tggtaaaaac acgaataagc cacatagttt aatctatgtg gctcttatat
      961 agttaaatga aaactttata aacaatatag ccaacataga tacaatccca aaattttagt
     1021 agtcttaagg ggtctgtatc tatgttaaaa cgtaggtaca aaccctaaaa atagtggcta
     1081 taataataat attttctatt gtttaataaa gtattcataa ttatctctcc cttttaatat
     1141 tttaattagt cagaaaatta tatgtattct cgacttgtta taaattataa attatacaat
     1201 aataaaagtc aactgctaaa tttaattaaa atactaaata atgtatactc agaatacttt
     1261 taaattaatg tattgtttgc aaaaaacgtt atcctaagtt ataagtgaat gtggaaattt
     1321 tatcaaaata tttactaaat atggaataac tagacatgca tatcaatcaa atatcataaa
     1381 aaaaagctgt ctggagaata ttaaaattct tttggacagc tcaagtagtg attagaaagt
     1441 tatataactt tcataatcag tcgtcaatat agacaacttt tatggaaaat gaataacttt
     1501 atatgcaata ttcaaattgc tacaataagc acaattttca aagggttagg gtggataaga
     1561 gtacttatta tataaagttt tcatattacc tacttcatat tacctatttt ttgaaattaa
     1621 taagttttat tttgcagatt ttgcattttc atctgacttt atatacttta tattatctgc
     1681 tgataacttt tgcatgtcaa gtgcttttag tgtatcttcg ttaattatta tttcagtttc
     1741 atctaatgta gtaactggta tatcgccaac agattttcct tctaatactt caatagcaag
     1801 ttctccagcc ttataaccta gtttttcata atctattcca caacaagcta aagcaccaga
     1861 agatacagaa ccttcttcag aggctattat aggaatcttg ttttcattag caactttaga
     1921 aactattggc atagaagaaa ctattaaatt gtcagtaggg acatataaaa catctatttt
     1981 gccaactaaa ctagaaatag cttggttaac ttcacttgaa gagctgattc ctttttcaac
     2041 tacttcataa ttatttttct tagcataatc atgtagagaa tcaacttgga tttttgaatt
     2101 aacttcacta gtattgtata taacccctat tttctttgct tttggagtca atgttttaac
     2161 caattctaat gttttatcaa ttgaaagata atcagatgta ccagaaacat ttccacctgg
     2221 tttttcaaga gatttaacaa gtccagcttc tacagggtct gtaacagcag tcattattat
     2281 tggaatatct ttagtagcat tataagctgc ttgtgcagat ggagtagata tagcatatat
     2341 caaatctttt ttgtcggata caaacttact agcaatactt tgtgtagtag gcatatcatt
     2401 ttgtgcattt tggaaatcta tttttatatt atctccatct ttatagcctt tatcttcgag
     2461 tgctttgatg aatcctttct ttgctttatc cagagacgga tgttccacta attgactaat
     2521 acctatattt ttttgttttt tgctatctgt ttctttattt tcatttgaag cattggagcc
     2581 atcattttga gaacatccag taagcattga tacaccaagt actcctgcta taattaaact
     2641 taatattttt ttacttttta tcattttatt ttcctccctt aaaatttatt gattatattt
     2701 gctcatatat tcatatgata cattataaat atttctgatt aaaactaaga ttttaatttc
     2761 ttatactgca tattcaaatt tttctaagat ttcttcaact gttaaatctt ctttttcttt
     2821 atcttttaca tctaatacaa cttcaccctt atgaagcatt atcaacctat ctccatattg
     2881 aagagcgtgt ttcaagttgt gagtaaccat aagtgtagtt atattttttt ctcttacgat
     2941 tttatctgtt aactctatta cttcatttga tgtttttggg tcaagtgctg ctgtatgttc
     3001 gtctagtaat aagaccttag gacttgctaa gctagacata attagtgata gtgattgtct
     3061 ttgacctcct gaaagatatt gtactttaat atctaaatat ttttttaaat ccaaagaaat
     3121 tccttcaagt aagtgttcca agtcattcgt tttatgacga agacattttt ttaagttcaa
     3181 taatttccct ttattaagtg ctagagataa attttctcta accgtcatag aaggacaagt
     3241 tccaaggctt gggtcttgaa aaactctact tactatttga gttcttttat actcagctaa
     3301 atttgttata gtagtactat ctaaagtaat ttgaccagaa gattctttta taagcccaga
     3361 tattatattt aataaagtag atttaccagt tccattacta cctatgatac ttacaaattc
     3421 accatcttct atatcgattg ataaattttc aaagatagta ttaggttcac catatggatt
     3481 agggaaactc tttgaaagat ttttaatttg taacatctac aacacctctt ttttctgatt
     3541 tatttttggt actagctttg ca
//
LOCUS       DAEORM030000131         3426 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.137, whole genome shotgun sequence.
ACCESSION   DAEORM030000131 DAEORM030000000
VERSION     DAEORM030000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3426)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3426)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 3426)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3426
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.137"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            <1..513
                     /locus_tag="KRH23_003786"
     CDS             <1..513
                     /locus_tag="KRH23_003786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HHS5227049.1"
                     /translation="RTSRALSYLYLIDKGYDTFKEFSISYMISKNRTKYYKAILDVEN
                     KGNNLTVFIEFMLKSIIQSINEMRNMHDRKSLESILKEELFENDITLSATEEHILKYI
                     CNKDNYSMTLENYIKKNKSRYLKAGIKEIELVDQLMEVFNNLEGIEILSKEKNIYKVN
                     DKYLKMLDID"
     gene            539..727
                     /locus_tag="KRH23_003787"
     CDS             539..727
                     /locus_tag="KRH23_003787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5227050.1"
                     /translation="MNNKKKAFLISGAINVISLIIVFSLFHYNIIENSTQNMIITVIL
                     IFIFEMIKIKIIEKYYKL"
     gene            1511..>3426
                     /locus_tag="KRH23_003788"
     CDS             1511..>3426
                     /locus_tag="KRH23_003788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein CwpV"
                     /protein_id="HHS5227051.1"
                     /translation="MKIPKKIAAMLTVTMIAGSSTAGIASAQTVATNLTGQERYETAV
                     KISQDGWKNADEVVIVNDSSIADALSATPFAKAKNAPILLTSKDKLNDKTKAEIQRLK
                     AKKVYLIGGTSVLSTNIEKEIKDLKISFERISGAERYQTSLELAKKLDAISDVKKIAV
                     VNGEKGLADAVSVGAPAAQNNMPVILADSKNGTAVADKFIKDAGITQSYVVGGESSIS
                     EAVKNKLPNSTRLGGTDRNDTNAKVIKEFYKKTDLKNAYVTKDGMNKQDQLIDALAVG
                     VLGAKNQSPVVLVGKNLSASQKSLVNSKSFDKITKVGGNGNETAFNEMKSLQEVKTVE
                     AKTISELKSAIDKATANDVINFKPTSEVKEAFTIQTDKAVTVNLNGTYTKTVTINMPN
                     GDVNNYAKVDDVVIDDVKDGTFVNYGKITNLKVNDKNGAKIENNSKGEIGSLTVASGA
                     SQVKVTNGGKITTVTNNSKGTTIDNKGTISSVKGDNSPTISGNSPSSNSSGGSSSSGG
                     SSGGSSGGSSSSKVGQIKFSATDKQIKMASGDKTVDPSDNTYILKLTNGTVKDGDVKA
                     NVKVAGLPSGLDYTAVGNRSANTITITVSGTASQSIQNDLNNVSVLVKAGAVSGTGAT
                     DSIANTTFEIKKYVA"
BASE COUNT         1474 a          364 c          573 g         1015 t
ORIGIN      
        1 agaacatcaa gagccttatc atatctatat ttgattgata aaggatatga tactttcaag
       61 gagttttcaa tatcatatat gatatctaaa aacagaacta agtattataa ggctatactt
      121 gatgtagaaa acaaaggaaa taatttaact gtatttatag agtttatgct caagtctata
      181 atacaatcta ttaatgagat gcgtaatatg catgatagaa aatctttaga aagtatatta
      241 aaagaggaat tgtttgaaaa tgacataact ctatcagcaa cagaagaaca tatattaaaa
      301 tatatttgca ataaagataa ctattctatg acattagaaa attatataaa aaagaataaa
      361 agtagatact taaaggctgg aataaaggaa attgaattag ttgaccagtt gatggaagtg
      421 tttaataatc ttgaagggat agagattttg tctaaagaaa aaaatatata taaagttaat
      481 gataagtact taaaaatgct tgatatagac taatttagat aatctggaga gggaatatat
      541 gaataataag aaaaaggcat ttttgatttc tggggctata aacgtaattt cattaattat
      601 tgttttttca ttgtttcatt ataatattat agaaaatagt acacaaaata tgataataac
      661 tgtaatctta atttttattt ttgaaatgat aaaaataaaa atcatagaga aatactataa
      721 actataaaca agaaatatct tttctaagag catattgtac aatatgctct taatttagtt
      781 atatagattt aatataaata atgtattttt tgtagatgat ttatgtaaga tttatgacca
      841 atttgtgtat gatttgtgtt ctttaatcat gacaatatta tattgtaaaa aataaattta
      901 ataaaaaatg acttggaatt tatattctag gtctttttta tataaaaatt taataagttt
      961 caaatgttgg taactttgac agtagaaaac gtctattgag ataacgagga ttctaattga
     1021 gggggagata tattagcact taaagtagta tatgcaacag atataatctt tacaaaagta
     1081 atttgaatta aaatgtaaat ataaagaata attaaaaaaa tatcgtaatt atttgttttt
     1141 catatggata aaattggtta tttaatatat aattacaagt ataaataata aaatttattt
     1201 gtaaaaagag tagcactttt aattctaaag gctacttttt ttatacaaaa ccctattttt
     1261 tataacaatt cattaacata aaaatcaaac ttaccttaaa atataaattt acaaattttt
     1321 caatcaataa gaaaatttct ttattcctta cataatgact gcaatgtaac aaaataatta
     1381 taaattaatt atgaaatcat tatagttaga aacctcttta aaattagata ttaagtatcc
     1441 tttagaatta gaacgggaac aaagttaaaa aattaagtaa tatcaaatgg acaaggggga
     1501 agaaaataaa atgaaaatac caaagaagat tgctgcaatg cttacagtta caatgatagc
     1561 tggaagttca acagcaggca tagctagtgc acaaactgtg gcaacaaatt taacagggca
     1621 agaaagatat gaaactgctg ttaaaataag tcaagatgga tggaaaaatg ctgatgaggt
     1681 agtaatagta aacgactcat ctatagcaga tgctctatct gcaacaccat ttgcaaaagc
     1741 aaaaaatgct ccaatacttt taacaagtaa agataaatta aatgataaga cgaaagcaga
     1801 aatacaaaga ttaaaagcta aaaaagtata cttaataggt ggaacttctg tattaagtac
     1861 aaatatagaa aaagaaataa aagatttaaa aatatctttt gagagaatct ctggagctga
     1921 gagatatcaa acatccttag aattagcaaa gaaattagat gctataagtg atgttaagaa
     1981 aatagctgta gttaatggtg aaaaaggact tgcagatgct gtaagtgtag gagcaccagc
     2041 tgcacaaaac aatatgccag taatacttgc tgattctaaa aatggaacag cagtagcaga
     2101 taaatttata aaggatgctg gaataactca atcttatgta gtaggtggag agagttcaat
     2161 ttctgaagct gttaaaaata aactaccaaa tagtacaaga ctaggtggaa cagatagaaa
     2221 tgatacaaat gcaaaagtaa taaaagaatt ttataaaaag acagatttaa aaaatgctta
     2281 tgtaactaaa gatggtatga ataaacaaga ccaacttata gatgcactag cagtaggtgt
     2341 attaggtgct aaaaatcaat caccagtagt tttagttgga aagaacttat cagcttcaca
     2401 aaaatctcta gttaactcta agagttttga taagataact aaagttggtg ggaatggtaa
     2461 tgagacagca tttaatgaaa tgaagtcatt acaagaagta aaaacagttg aagctaaaac
     2521 aatttctgaa ttaaaatcag ctatagataa agctactgct aatgatgtta taaactttaa
     2581 gccaactagt gaggttaaag aagcatttac aatacaaact gataaagcag taacagtaaa
     2641 cttaaatggt acatatacaa agactgtaac tatcaatatg cctaatggag atgtaaataa
     2701 ctatgcaaaa gtggatgatg tagttataga tgatgtaaaa gatggaactt ttgttaacta
     2761 tggaaaaata actaacttaa aggttaatga taaaaatgga gccaagatag aaaataattc
     2821 taaaggagag attggtagtt taacagtagc atctggagca agtcaagtaa aagtgactaa
     2881 tggtggtaag ataactacag ttacaaataa ttctaaaggg actactatag ataataaagg
     2941 tacaataagt agtgttaagg gagataattc tccaacaata agtggaaata gtccaagttc
     3001 taactcttca ggaggaagtt catcaagtgg aggttcttca ggaggaagta gtggaggaag
     3061 ttcttcatca aaggtaggtc aaataaaatt tagtgcaaca gataaacaaa taaaaatggc
     3121 atcaggagat aagacagtag atccatcaga taacacatat atactaaaat taacaaatgg
     3181 gacagtaaaa gatggagatg taaaagctaa tgttaaagta gcaggattac catcaggact
     3241 agattataca gcagtaggaa atagatcagc aaatacaata acaattacag tatcaggaac
     3301 agcaagccaa tcaatacaaa atgatttaaa taatgtaagt gtgctagtta aagcaggagc
     3361 agtatctgga acaggagcta cagattcaat tgcaaataca acatttgaaa ttaaaaaata
     3421 tgtggc
//
LOCUS       DAEORM030000132         3420 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.138, whole genome shotgun sequence.
ACCESSION   DAEORM030000132 DAEORM030000000
VERSION     DAEORM030000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3420)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3420)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 3420)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3420
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.138"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            241..1866
                     /locus_tag="KRH23_003789"
     CDS             241..1866
                     /locus_tag="KRH23_003789"
                     /EC_number="2.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003886 - DNA
                     (cytosine-5-)-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HHS5227052.1"
                     /translation="MYNVIDLFAGAGGLSLGFEMTKKFNMVAFVEKNDNAAKTYLENH
                     PSVKRYCDIKRLDFQDILNSVDKIDVVIGGPPCQGFSNANRQKRKIINGNNELVKLYV
                     DAIDKLKPNVFVMENVKTISSNKHSFYLTKKDKNHIINNLKLNIYNKDSVLYDRTEYI
                     NELFNIISIEDIESYIISNIDLKNLKIIIKKKKDICDYLNKISNYKKVKSTIEKLETR
                     GKMPKWYLELINKVKNILENMLYNRNLSDEQIFYLNLFLDIQNLFLGIYELKSESVIF
                     ENTLDDNKIIAKMDTYIIIDYINASFEYLGYVLNGSALNSIDYGVPQNRERFVLIGAK
                     KDFLKNKKIETPKPIVGENYVTVRDAIGDLAEYEASKGSMDYCFEKNSNNIEKDFYRK
                     IILDSNKIYNHVCTDTRNIALKRFEYINQGNNFHSLPDELKGTYADPERTQNTIYKRL
                     VYDKPSDTVVNVRKSMWIHPIKNRAVSAREAARLQSFPDSYKFLGTKDSVYQQIGNAV
                     PPLLGRVVAEKILNLFNDEPNEYLRDVFEALDG"
     gene            complement(2865..>3420)
                     /locus_tag="KRH23_003790"
     CDS             complement(2865..>3420)
                     /locus_tag="KRH23_003790"
                     /inference="COORDINATES: protein motif:HMM:NF016119.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="sortase domain-containing protein"
                     /protein_id="HHS5227053.1"
                     /translation="LKKLVKILINIICIITLTFSSLSIYIKLSEYKKADEVYTELREN
                     TSNNSKHQELYDKNNDYRFWLKINNVNIDYPVVQGYNNDFYKNYLPLGSIFMDYRNNF
                     ENDKSLIIYGHYMKNKTMFGQLENYTDEVFFKENNLVEINYKVQTYTYEIFSVYTADL
                     INRDYLSIHFNSNYEFKDYLNYIT"
BASE COUNT         1358 a          365 c          462 g         1235 t
ORIGIN      
        1 aaaataatat atggtatata atataaaaaa agattgataa ataaataaaa aatatattat
       61 gttatttatt tgaatagatt atccagaaga cataaataag aaaaataatg tgtaagtaaa
      121 aatattagaa tttattaaaa gctattacaa gtataagaaa tttgaaatga ttattcaaaa
      181 attgacatgt gaaaaaaaat atgatatgct gcaataaaag ttaatgtgag gtatgtcaga
      241 atgtataatg ttatagatct ttttgcaggt gcaggtggtt tgagcttagg atttgaaatg
      301 actaaaaaat ttaatatggt ggcttttgta gaaaaaaatg ataacgcagc aaaaacatac
      361 cttgaaaatc atccgagtgt taagcgttat tgtgatatta aaagattaga ttttcaagat
      421 atattaaaca gtgtcgataa gatagatgtt gttataggag gaccgccatg tcaaggtttt
      481 tctaatgcta atagacaaaa aagaaaaatt ataaatggaa ataatgaatt agttaagcta
      541 tatgttgatg ctattgataa attaaagcca aatgtatttg taatggaaaa tgtcaaaact
      601 atatcttcaa ataagcattc attttatttg actaaaaaag ataaaaatca tataataaat
      661 aatttaaaat taaatattta taacaaagat agtgttttat atgatagaac tgagtatata
      721 aatgaattat ttaatattat tagtatagaa gatattgaat catatattat atcaaatata
      781 gacttaaaaa atttgaaaat aattattaag aaaaaaaagg atatatgtga ttatttaaat
      841 aaaatatcta attataagaa agtaaaatct accatagaaa aattggaaac aaggggaaaa
      901 atgccaaaat ggtatttaga attaataaat aaagtaaaaa atatattaga aaatatgtta
      961 tataatagaa atttatcaga tgaacaaata ttttatttga acttattctt ggatattcaa
     1021 aatttatttt taggaatata tgagttaaaa tctgaatctg taattttcga aaatacactt
     1081 gatgataata aaattatagc taaaatggat acttacatta taatagatta tataaatgca
     1141 tcctttgagt atctaggata tgtattaaat ggaagtgcac taaattcaat tgattatgga
     1201 gtacctcaaa atagagaaag atttgtattg ataggagcaa aaaaagactt cttaaaaaat
     1261 aaaaagatag aaactcctaa gcctatagtt ggagaaaatt atgttacagt aagagatgca
     1321 ataggcgatt tagctgaata tgaggcttct aaaggtagta tggattattg ttttgaaaaa
     1381 aatagtaata atattgaaaa agatttttat agaaagataa tattggatag caataaaata
     1441 tacaatcatg tatgtacaga tacaagaaat atcgcactaa aaagatttga atatataaat
     1501 caaggaaata attttcattc tttgccagat gagttaaaag gaacttatgc tgatccagaa
     1561 agaactcaaa atactattta taaaagacta gtatatgata agccatcaga tactgttgta
     1621 aatgtaagaa aatctatgtg gatacatcct attaaaaaca gagctgttag cgcaagagag
     1681 gcggctagat tgcagtcatt ccctgatagt tataagtttt taggtacaaa agattctgta
     1741 tatcaacaga taggaaatgc agtaccacct ttattaggtc gagtagtagc agaaaagata
     1801 ttaaatttat ttaatgatga accaaatgag tatcttagag atgtgtttga agcactagat
     1861 ggatagttca aataaaatag tgggtattat tcttgtgatt cttatccaac attaatccac
     1921 gaaataagga ctgtcgaatg agtaatttta aattgctgtg cgacagttct ttttttactt
     1981 gcttttcatt aatttatatt tatgcaaaat ttgagcttga aaacggtcat aagaaataaa
     2041 ggtataaaaa taccatttta aaatagaata atttacaaag tgtaagatta aaaaatattt
     2101 ttgagaggat gaatatacat actacattta ttaatgatta tcttatttgt gaaacttata
     2161 aatactatgt ctaacactac aggtataaac tatgaaagaa cattttgatt gcctctgatt
     2221 agaattcttt taaagttcat actatgtttt atttggatga aagctcctta tgcctgaata
     2281 cttctattca ttctaagttc acatccttgt gtaccagtga ttctttctaa attatcttaa
     2341 tgccaaaatc ttgttcgcat ttcaaaataa agttaggtag ctacttcaac attttagtta
     2401 tatttcttca atagtttgtc tccaaacaaa ggtacatcta ttagcaacag atttaatttt
     2461 atttatatca ataaataata tatactttga aacttcatta atatcaccaa gataatttat
     2521 aagttaaact attatatact atcttcacca actacatcct ccatagtttt acactttctt
     2581 aattcagctt ggtaatctaa atctgtaata attatttctc tttgattttt catttctttg
     2641 cctacaaaag tttaatatga atattattct atacttacca attttacgtt caaaaaagac
     2701 tataggtaag tctgcattta cacaaaccta cttatcagtc tcttttttga aattaattta
     2761 gtatgaacta tagtacgagc atctttaaat tcatagttac aagtatacaa agttataatt
     2821 ttatctgaaa tatctacctt tatatcagat ttgtgtactg atttttaggt tatataattc
     2881 aaataatctt taaactcata attactatta aagtgtatac ttaaataatc tctgttaatt
     2941 aagtcagcag tatatactga aaaaatttca taagtataag tttgtacttt ataatttatt
     3001 tctactaagt tattttcttt gaaaaatact tcatcagtat agttttctag ctgaccaaac
     3061 atagttttat ttttcatata atgaccatag attattaaac tcttatcatt ttcaaaatta
     3121 tttctataat ccatgaaaat actacctaaa ggaagataat ttttataaaa atcattgtta
     3181 tatccttgta ctacaggata gtctatattt acgttgttta ttttaagcca gaatctataa
     3241 tcattatttt tatcataaag ttcttgatgt ttgctattat tgctagtgtt ttctctgagt
     3301 tccgtatata cttcatcagc ttttttatat tcagataatt ttatgtaaat cgaaaggcta
     3361 gagaaagtta gcgtaataat gcaaataata tttattaata tttttactag ttttttcaat
//
LOCUS       DAEORM030000133         3079 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.139, whole genome shotgun sequence.
ACCESSION   DAEORM030000133 DAEORM030000000
VERSION     DAEORM030000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3079)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3079)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 3079)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3079
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.139"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            complement(145..666)
                     /locus_tag="KRH23_003791"
     CDS             complement(145..666)
                     /locus_tag="KRH23_003791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HHS5227054.1"
                     /translation="MATIDLIVLGIVKQQPKSAYDIQKAVEYRNISRWVKISTPSIYK
                     KVIQLEQKGYIESKTVKNGKMPEKAVYSLTELGETHFLDLMFDTSSKPINILLDFNAV
                     IVNLNSLTPEKQKLCLNNIEENVQELKKTIEENISIKTEVPETAKAVLEQQLVLAQAL
                     ETWINSLKDNMGN"
     gene            794..1969
                     /locus_tag="KRH23_003792"
     CDS             794..1969
                     /locus_tag="KRH23_003792"
                     /inference="COORDINATES: protein motif:HMM:TIGR00797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA];
                     GO_function: GO:0042910 - xenobiotic transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006855 - xenobiotic transmembrane
                     transport [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HHS5227055.1"
                     /translation="MKESNKKIELLGSAPISKALLSMGLPTMIGMMITALYNLVDAYF
                     VGGLGTSQMGAISVAFPLGQLVVGLGLLFGNGAASYIARLLGHGDNEKAGKVVSTSIY
                     SSIIVGTLVIIVIMIFLNPILKLLGATKSIMPYAISYASIYVVSSIFNIFNVTMTNIV
                     TSEGAAKTTMCAMLLGALLNMILDPIFIYTFGLGVRGASIATAISQIASTLVYVGYIL
                     SKKSIFSFRINECCFSKEIFSEILKIGIPTLIFQLLTSLAITLTNMEATKYGDSVIAG
                     MGAVTRITSLGSLVVFGFIKGFQPIAGYNFGSKNYDRLHIAIKTSILWTTVFCVVLGL
                     ILILFPKSIISQFTSGDILLIENGSKALRANGFSFMLFGFYTVYSTLFLALGKAKEG"
     gene            1979..2158
                     /locus_tag="KRH23_003793"
     CDS             1979..2158
                     /locus_tag="KRH23_003793"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5227056.1"
                     /translation="MCRQGVCFIPIILIIPVFYGLNGILYAQPIADLMAAIIAGFMSI
                     RLHKELNLLKINGMH"
     gene            2347..3024
                     /locus_tag="KRH23_003794"
     CDS             2347..3024
                     /locus_tag="KRH23_003794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HHS5227057.1"
                     /translation="MISQNEIDILTHSLPFWDKLTDLQKELLISSANTSHYKKGNPVH
                     CGDSDCIGILIIKSGTVRTYILSDEGREVTLFRLDDGDVCILSASCILKTITFDVYVD
                     AETDCDIIQISSSVFAKLSTENIHAELFSYKLATERFSDVMWAMQQILFMSFDKRLAS
                     FLIDEIAKNGSSTINMTHEQIAKYMGSAREVVSRMLKYFAREGIVSLSRGGIKVLDKD
                     KLRSLTL"
BASE COUNT          957 a          441 c          499 g         1182 t
ORIGIN      
        1 aaaagtttaa cattctccct caattaaatg agctttattt taaatatact tttcagttta
       61 tatcatttgt tttatttttt ctaatatctc attattaaat atgctggttt ttgtttaatg
      121 attattaagt tagcttctct aattctaatt tcccatatta tcttttaaag aatttatcca
      181 ggtttccaat gcttgtgcta gcaccaactg ttgctccaac actgcttttg ctgtctctgg
      241 tacttctgtc tttatactta tattttcctc aatagttttc tttaactctt gaacattctc
      301 ttcaatatta ttgagacata atttctgttt ttctggtgta aggctattta aatttactat
      361 aacagcatta aaatctaaaa gaatatttat tggtttgcta gatgtatcaa acattaaatc
      421 tagaaaatgt gtctcaccta attcagttaa tgaataaact gctttttctg gcatttttcc
      481 attcttcaca gttttacttt caatatatcc cttttgttct aattgaatta cttttttata
      541 aattgatggt gtacttattt taacccaacg tgatatattc ctgtattcca ctgccttttg
      601 aatatcataa gcactcttgg gttgttgctt tactattccc aatacaatta aatctattgt
      661 agccataaaa atcatctcct ttagttttct tactattgac aaatactata aattatagta
      721 ctattttcca tgcttactat aatttatagt attataattt agacttaatg tcaatagaag
      781 aggagtgtta agtatgaaag aaagtaacaa aaaaattgaa ttattagggt ctgccccaat
      841 ctcaaaagca ttgttatcta tgggattacc taccatgata ggtatgatga taactgcatt
      901 atacaatttg gttgatgcat actttgtggg tggacttgga acaagtcaaa tgggagctat
      961 atccgttgca tttccattag gtcagcttgt tgtgggatta ggattattgt ttggaaatgg
     1021 agctgcttca tatattgcca gacttttagg ccatggtgat aatgaaaaag caggaaaagt
     1081 ggtaagtaca tctatttaca gtagtattat agtgggtaca ttagttatta ttgtgattat
     1141 gatttttctc aatccaattt taaaattgtt aggagctaca aaaagtatta tgccttacgc
     1201 aatatcttat gctagcattt atgtcgtgtc atctattttt aatatattca atgtcactat
     1261 gactaatatt gtcacaagtg aaggagctgc taaaacaact atgtgtgcta tgttattagg
     1321 tgctttgctt aatatgattt tagacccgat attcatttat acttttggtc tgggggtaag
     1381 gggtgcttct attgcaacag ctatctcaca gattgcttca acacttgttt atgtaggata
     1441 tattttaagc aagaaaagta tatttagttt tagaattaac gaatgctgtt tttcaaaaga
     1501 aattttttca gaaatcctaa aaattggcat acctacctta atatttcaat tattgactag
     1561 tcttgccatt acattaacta atatggaggc tacaaagtat ggtgattctg tgatagctgg
     1621 aatgggtgct gtaacacgaa taacgtcttt aggtagtctt gttgtatttg gttttataaa
     1681 aggtttccaa ccaattgctg gttataattt tggttcaaag aactacgata gattacatat
     1741 agcaataaaa acttccatat tatggactac agtattttgt gtagtgcttg gtcttatatt
     1801 gatactcttc ccaaaatcta taatttcaca atttacaagt ggtgacattt tattaataga
     1861 aaatggtagt aaagctctta gggcaaatgg gttttcattt atgctatttg gattctatac
     1921 agtgtattct acattattcc tcgcactagg aaaagcaaag gaaggttgat ttttaggtat
     1981 gtgtagacaa ggtgtctgtt ttatccctat aattttgatt attcctgtat tctatgggtt
     2041 aaatggtatc ttatatgcac aaccaatagc tgatttgatg gctgctataa ttgctggttt
     2101 tatgtctata aggttacata aggaacttaa tcttttaaaa ataaacggta tgcattagtt
     2161 atacaaacct actatcatca aaacatatta ctttctcatt aatagcaaga atatatatta
     2221 tcatattttt tctacataaa tcatactatt actatctgac taaataatcc tcttaacaaa
     2281 ctacttgtca atttatctat tcacttgtat catgggatta taacaattta agaaaggaga
     2341 tattgtatga tttcacaaaa tgaaattgat atacttacac atagcttgcc tttttgggat
     2401 aaacttactg acttacaaaa agaattatta atttcttcag caaatacctc gcattacaaa
     2461 aaagggaatc cagtacattg tggtgatagt gactgtattg gtattttgat tataaagtct
     2521 ggaacagtgc gtacatacat actttcagat gaaggtcgag aggttacact gttccgactt
     2581 gatgatggag atgtatgtat tttatcagct tcctgtattc taaaaacaat aacttttgat
     2641 gtctatgtag atgctgaaac ggactgcgat attatacaga ttagttcctc tgtttttgca
     2701 aaattatcta cagaaaatat tcatgcagag ttattttcat ataaattagc taccgaacgt
     2761 ttttctgatg ttatgtgggc tatgcaacaa attcttttta tgagttttga taagcgtttg
     2821 gcatcttttt taattgatga gatagctaaa aatggcagta gcactataaa tatgactcat
     2881 gaacaaattg ctaagtatat gggtagtgcc agagaagttg tatcgagaat gttgaaatat
     2941 tttgctagag aaggtattgt gtctttatct cgtggtggta taaaagtatt ggataaggat
     3001 aaacttcgtt ctttgacact gtaaaagtgt gtctcaaaat gaacttttta gttcatgagg
     3061 cactcttttt tgtgtaaaa
//
LOCUS       DAEORM030000134         3028 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.140, whole genome shotgun sequence.
ACCESSION   DAEORM030000134 DAEORM030000000
VERSION     DAEORM030000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3028)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3028)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 3028)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3028
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.140"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            250..2607
                     /locus_tag="KRH23_003795"
     CDS             250..2607
                     /locus_tag="KRH23_003795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HHS5227058.1"
                     /translation="MDKVNLERYSCDINVGLNKNQLQSRIDDNLINAFDNGKTKTYKQ
                     IFKDNIFTLFNLINIVLVCLLVSVGSFKNTLFIFIAVINTIIGVIQEIRAKRLLDNLS
                     VIVSNKVSVIREKEKKEIDVQELVLDDIMILKTGNQICADSKVLNGKLEVNESLVTGE
                     SDIIIKNKGDFLYSGSFVVSGEAFVRVENIGKDNYANKIANDAKISKKHNSQLRNSLN
                     AILKIVGIIIIPLGIILFAKQHFGNGDSIATSVVGTVAAVNGMIPEGLTLLTSIALAV
                     GTIKLASHKTLVQELYCVETLARVDTLCLDKTGTITEGKMQVDDIVMLEEVDINEIMG
                     NICNSLKDDNATLNAIRDKYNVLDTYKAKNLIPFSSERKYSGVTFENKGTYLLGAFEF
                     IFKEKNKKLRIEVERYSKKGNRVIVLAHSDSYMEDNNIPEDIKPLAFILILDKIRDEA
                     KETLEFFYNEGVDIKIISGDNPITVSEVARKAGLKTASNFIDATTLKNDSDIYKAVDK
                     YSVFGRVSPQQKKQMILALKKQNHTVAMTGDGVNDVLALKEADCSIAMASGSDVTKNV
                     SNLVLLDSNFASMPKVVMEGRKVINNIQRASSLFLVKTIFSFFLSLLTLFFFSRQYPF
                     VPIQLSLIGAVTVGIPSFFLALEANKSRISGNFLLNILKNALPGALCVTVNVIIVYNI
                     VEYLGYSSSVFSTMCAILTGVCGLLILRQQCLPFNKERLFLIVSMTIAFVIGILFLGG
                     LFSFVALSRELILITMALAILMPIMIKVMLFVLDEILETIVPDLN"
     gene            complement(2693..3010)
                     /locus_tag="KRH23_003796"
     CDS             complement(2693..3010)
                     /locus_tag="KRH23_003796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine/purine nucleoside phosphorylase"
                     /protein_id="HHS5227059.1"
                     /translation="MSEFKNVTAVKKANVYFDGKVSSRVIILPNGERKTLGLMLPGEY
                     TFSTREEEIMEMLAGSMDVKLPGSNEFVTYKEGQKFNVPSDSSFDLKVNEVVDYCCSY
                     IAD"
BASE COUNT         1145 a          336 c          485 g         1062 t
ORIGIN      
        1 tagatattaa taagaattgt tgaatttatc ttgccttaac tttatttact cttttatatt
       61 aagaaaaact taactaaaat atagcgaaat tcataaaaat ttaggaaatc ttaagaatta
      121 taatatttaa atctttagat ttatatttta ttatataaac tatagaataa taaaataaaa
      181 aaattgagaa ttttataata tatttgtaga tttgagtata aaaaagtgct aagttgaaag
      241 gagtaaaata tggataaggt taatttagaa aggtatagtt gtgatataaa tgttggttta
      301 aataaaaatc aacttcaaag tagaatagat gataatttaa ttaatgcatt tgataatgga
      361 aaaaccaaaa catataaaca aatttttaaa gacaatatat ttacactttt taatctcata
      421 aatattgttt tagtctgttt attagtttca gttggttctt ttaaaaatac cttatttata
      481 tttattgctg taattaatac tattatagga gtaatacaag agataagagc taaaagatta
      541 ttggacaatc tatctgttat agtttcaaat aaggtatctg tcataagaga aaaagagaaa
      601 aaagagattg atgtacaaga attagtatta gatgatatta tgattttaaa aacaggtaat
      661 caaatttgtg cagattcaaa agttttaaat ggaaaattag aggtaaatga gtctttggtt
      721 acaggtgaat ctgatattat tataaaaaat aaaggcgatt ttttatattc tggaagtttt
      781 gtagtttctg gagaagcttt tgtaagagtt gaaaatatag gaaaagataa ctatgcaaat
      841 aagatagcta atgatgcaaa gatttctaaa aaacataatt ctcaacttag aaattcatta
      901 aatgcaatat taaaaattgt aggtataata ataattcctt taggaattat attgtttgca
      961 aaacaacatt ttggaaatgg agattctata gctacatctg tagtaggtac agtggcagct
     1021 gtaaatggta tgataccaga gggattaaca ttacttacga gcattgctct agctgtagga
     1081 actataaaac ttgctagtca taaaacttta gtgcaagaac tgtactgtgt agagactctt
     1141 gctagagttg atacactatg tcttgataag acaggtacaa ttacagaagg taaaatgcaa
     1201 gttgatgata tagtaatgtt ggaagaagtg gatattaatg aaataatggg gaatatatgt
     1261 aattctctca aagatgataa tgcaacacta aatgcaataa gagataagta taatgtttta
     1321 gatacgtata aagctaagaa tttaatacca ttttcttcag aaagaaaata cagtggggtt
     1381 acctttgaaa ataaaggtac atatttatta ggtgcatttg aatttatatt taaggaaaaa
     1441 aataaaaaac ttaggataga agttgaaaga tattctaaaa aaggaaacag agtaatagtt
     1501 ttagctcata gtgattctta tatggaagat aataatattc ctgaagatat aaagccacta
     1561 gcttttatat tgatattgga taaaattaga gatgaagcta aggaaacttt agaatttttt
     1621 tacaatgaag gtgtagatat aaaaattata tctggtgaca atcctataac agtaagtgag
     1681 gtagctagaa aagcaggtct taaaacagct agtaatttta ttgatgcaac aacacttaaa
     1741 aatgatagtg atatatacaa agcagttgat aaatacagtg tttttggaag ggtaagccca
     1801 caacagaaaa aacaaatgat tttagcatta aaaaaacaaa atcatacagt agctatgact
     1861 ggagatggtg taaatgatgt gctagcactt aaagaagcgg attgtagcat tgccatggca
     1921 tctggaagtg atgttactaa gaatgtgtct aatttagtct tattagattc aaactttgca
     1981 tcaatgccaa aagttgttat ggagggaaga aaagtaatta ataacattca aagagcatct
     2041 tctttgtttt tagtaaagac aattttttca ttcttcttgt cgttattaac attattcttc
     2101 ttcagtagac agtatccatt tgttcctata caattatcac tcattggggc tgtaacagtg
     2161 ggtataccat cattcttctt agctcttgaa gcaaacaaaa gtagaatttc aggaaatttt
     2221 ttactcaata tattaaaaaa tgctttacca ggagcactat gtgtgacagt aaatgtaatt
     2281 attgtttaca atatagttga atatttaggt tatagttcaa gtgtattttc cacaatgtgt
     2341 gctatattaa ctggtgtatg tggtctttta atattaagac aacaatgttt gccatttaat
     2401 aaagaaagat tatttttaat agtaagtatg actattgcat ttgttattgg gattctattt
     2461 ttaggtggat tattctcatt tgtagcattg agtagagaat taattctcat aactatggca
     2521 ttagcaatat taatgccaat tatgataaaa gttatgttat ttgtcttaga tgagatatta
     2581 gagacaattg ttccagattt aaattaattt taaaatgata taaataagag cagttttagt
     2641 tgaactgctc tttttagatg tgtttaattt tatgtaagaa tatgtatttt tattaatcag
     2701 ctatatatga gcaacagtag tcaacaactt cattaacctt taagtcaaaa cttgaatcac
     2761 taggaacatt aaatttttgc ccttctttat aagttacaaa ttcattgctt ccaggcagtt
     2821 ttacatccat acttccagca agcatctcca ttatttcttc ttctctagta gaaaaagtgt
     2881 attctcctgg caacattaat cctaaagttt ttctttctcc attaggcagt attattactc
     2941 tgctacttac cttaccatca aaataaacgt ttgccttctt tactgcagta acattcttaa
     3001 attcactcat tagataaaac ctccaaaa
//
LOCUS       DAEORM030000135         2904 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.141, whole genome shotgun sequence.
ACCESSION   DAEORM030000135 DAEORM030000000
VERSION     DAEORM030000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2904)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2904)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 2904)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2904
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.141"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            142..372
                     /locus_tag="KRH23_003797"
     CDS             142..372
                     /locus_tag="KRH23_003797"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5227060.1"
                     /translation="MQKYKIKFEEKVTLEHEVIVEIPEEISINDICHCIEQKCQRIYD
                     IADYIREFNGRQIDFTEDTCGGTEMLVESFRK"
     gene            627..812
                     /locus_tag="KRH23_003798"
     CDS             627..812
                     /locus_tag="KRH23_003798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5227061.1"
                     /translation="MVITEFKVTWQTTREWEKGNVYSSIFTNLEEARAFKKDEENIKE
                     NYNVKLLSRAIVEIEID"
     gene            826..1065
                     /locus_tag="KRH23_003799"
     CDS             826..1065
                     /locus_tag="KRH23_003799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015981545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5227062.1"
                     /translation="MNTLIYKYIVNEHRDEADELDRDYGEFKIFNGGKCFGGCGRNFY
                     TLAKFKKMIVTCPHCGKKYQIKLFKNGKVNMRVIE"
     gene            1194..1601
                     /locus_tag="KRH23_003800"
     CDS             1194..1601
                     /locus_tag="KRH23_003800"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0000400 - four-way junction DNA binding
                     [Evidence IEA];
                     GO_function: GO:0008821 - crossover junction DNA
                     endonuclease activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HHS5227063.1"
                     /translation="MKVFLVIDGEPVGKERPRMNSITKRIYTPNKTRDYEELIKWLYQ
                     SKVKYRFTGYIKMTLRCYYSIAKSNSKKVKEQKRNNVLRPSKKPDIDNVVKIIADSLN
                     EIAYKDDTQIVEVVASKYYSDKPRVEVILEDII"
     gene            1616..2341
                     /locus_tag="KRH23_003801"
     CDS             1616..2341
                     /locus_tag="KRH23_003801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antA/AntB antirepressor family protein"
                     /protein_id="HHS5227064.1"
                     /translation="MNEIMTNENLRVVADDLVTVYETDTGEKIVFARELHNNLEVKRQ
                     FIDWIEDRIKQYGFKENEDYSVFHKNMKNSTGGRPSKEYVLKLDVAKELAMVQNNNKG
                     REIRRYFIRLEKLLNRTLSNSQLSQINTIVNESLLKMEVKHNIQIEQLKKECSEYYRP
                     TSKTKYDISSYIKERLGISKVNEEFELVKKRTLLVLGADKWEDIPKDVLLNSLNLIDE
                     SIRIIKSERKTNQISFFEKDNFC"
     gene            2435..>2904
                     /locus_tag="KRH23_003802"
     CDS             2435..>2904
                     /locus_tag="KRH23_003802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5227065.1"
                     /translation="MDNNINKKELFKKVEGRLHHYKFLSAEIKNLELDIESRENEIFG
                     CKAVGYDEKVSPTYAFNSSVENEIIKKERDITRLKKLKKDKEIEKKKIENALTCLDIR
                     EEHFFKLFYNSRMKNSMVYISLEMNSDRKTCRCVRERLVYKIMDMLYPRIKENEL"
BASE COUNT         1251 a          241 c          574 g          838 t
ORIGIN      
        1 caagcgggaa atgctgttac tgcaaatgtt atatatgaaa tagcaaaaag aatgggctaa
       61 aagttgcaaa atgtctttta gtataaatta ttgttgaagt gttttgtaac tctcaaaaac
      121 taaaataaag ggggaattaa attgcaaaaa tataaaatta aatttgagga aaaagtgact
      181 ttagaacatg aagttatagt tgaaatacca gaagaaataa gtataaatga catttgccat
      241 tgtatagaac aaaagtgtca aagaatatat gatatagcag attatataag agaatttaat
      301 gggagacaaa tagattttac agaagatact tgtggaggga ctgaaatgtt agttgaatca
      361 tttagaaaat gaaagtagtg agcatatgac taataaagat atgtgcaagt caaagaatct
      421 tgatgaaaga gaagtgtata agagttttgg gaaagagatt tgtaaatgat aaaggagatt
      481 gtgaaagtaa agattgtgat gcaacatatg aaaattggtt ggagaaggat gctgaaagat
      541 aattataaaa ataaagtcaa ggtaagcttg tgaatgaaac tagaagtcta tagacttact
      601 ttgacttata aaaaggagtg gtcaatatgg ttattacaga atttaaggtg acttggcaga
      661 caactagaga atgggaaaaa gggaacgtgt acagctctat atttactaat ttagaagaag
      721 caagagcttt taaaaaagat gaggaaaata taaaagaaaa ttataatgtg aagcttttaa
      781 gtagagctat agtcgaaatc gaaatagatt aggtaggtgt ttttaatgaa tactctgata
      841 tataaatata tagttaatga acatagagat gaagcagatg agttagatag agactatgga
      901 gaatttaaaa tatttaatgg aggtaaatgt tttggtggat gtggtaggaa tttctataca
      961 ttagctaagt ttaaaaaaat gatagttact tgtccccatt gtggaaaaaa atatcaaata
     1021 aaacttttta aaaatggaaa agtgaatatg agagtaattg agtaaatcaa gggaagtgat
     1081 tatatgaaaa gaagaagatg cagttggtgt ggcaaactat tttatcttga tgaaaaatct
     1141 aaggagattt attgttgtaa ggaatgtagg aagaaggcta agaaggtgaa aaaatgaaag
     1201 tttttcttgt aatagatgga gagccagttg gcaaagaaag acctagaatg aactctataa
     1261 ctaaaaggat ctatacacct aataaaacta gagattatga ggagttaata aaatggctgt
     1321 atcaatctaa agtgaagtat cgttttactg gttatataaa aatgacttta agatgttatt
     1381 actctatagc taaaagtaac agtaaaaagg ttaaggagca gaaaagaaat aatgtgttaa
     1441 gacctagtaa aaaacccgat attgacaatg ttgttaagat tatagctgat tcactcaatg
     1501 agatagctta taaagatgat acacagattg ttgaggttgt agctagtaaa tactatagtg
     1561 ataagccaag ggttgaggtt atattagaag atattattta aggaggacta taaatatgaa
     1621 tgagattatg acaaatgaaa atttaagagt tgtagcagat gatttagtta cagtttatga
     1681 aactgataca ggagagaaaa tagtttttgc aagagaacta cataataatt tagaagttaa
     1741 gagacagttt atagactgga ttgaagatag aattaaacaa tatgggttta aggaaaatga
     1801 ggattattca gtttttcaca aaaatatgaa aaactcaact ggtgggagac cttcaaaaga
     1861 atatgtattg aagcttgatg tagcaaaaga acttgctatg gtacaaaaca ataataaagg
     1921 aagagaaata agaagatatt ttataagatt agaaaagtta ctaaatagaa ccttatcaaa
     1981 ttcacagctt agtcaaatta atactattgt gaatgaatca ttacttaaga tggaagttaa
     2041 acataatatc caaatagagc aacttaaaaa agagtgttca gaatattata gaccaacctc
     2101 taaaactaaa tatgatatat cttcttatat aaaagaaaga ctaggtatat caaaagttaa
     2161 tgaagaattt gaattagtta agaaaagaac tctattggta ttaggtgctg acaaatggga
     2221 ggatatcccg aaagatgtat tacttaattc attaaactta atagatgaat caatcagaat
     2281 tataaaatct gagagaaaaa caaatcaaat tagtttcttt gaaaaagata atttctgtta
     2341 ataaaaagaa aaaaggagtg ctttcacact ccacttgtca aaaatataaa gcttttatcc
     2401 aagattatta taacataaac aggagtgtgg aagtatggat aataatatca ataaaaaaga
     2461 actatttaaa aaagtagaag gtagactaca tcattataaa tttttaagtg cagaaattaa
     2521 aaatcttgaa ttagatatag aaagtagaga aaatgagata tttgggtgta aggctgttgg
     2581 atatgatgaa aaagtaagtc caacatatgc ttttaattca agtgtggaga atgagattat
     2641 aaaaaaagaa agagatatta ctagattgaa aaaactgaaa aaagataagg aaattgaaaa
     2701 gaagaaaata gaaaatgcac ttacatgctt agatataaga gaagaacatt tttttaaact
     2761 gttttacaat agcagaatga aaaatagtat ggtttatata tccttagaga tgaactcaga
     2821 tagaaaaaca tgtagatgtg tgagggaaag attagtgtat aaaattatgg atatgcttta
     2881 tccaagaatt aaggaaaatg aact
//
LOCUS       DAEORM030000136         2870 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.142, whole genome shotgun sequence.
ACCESSION   DAEORM030000136 DAEORM030000000
VERSION     DAEORM030000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2870)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2870)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 2870)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2870
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.142"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            786..1466
                     /locus_tag="KRH23_003803"
     CDS             786..1466
                     /locus_tag="KRH23_003803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HHS5227066.1"
                     /translation="MLIDTPEDIAVACNRQKISEVKHISISHHDPDHVKGIRIVEKIG
                     CDFITGENNPIGFYALPEVIEDINRTNLDCLKYYGNVINCISINETSHVKINNFDIDL
                     INNNPDRNITFYVIKENEKKVIYACCNPKPFTHSDMYFDADILIISLVSDDGILNDGT
                     KLKDTPFKDEIFTLDEIVEIKNYYRIKKIIVTHIDEMWGKSYGYYSELEKKLDNIYFA
                     YDGMEIIV"
     gene            complement(1776..2555)
                     /locus_tag="KRH23_003804"
     CDS             complement(1776..2555)
                     /locus_tag="KRH23_003804"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0070401 - NADP+ binding [Evidence IEA];
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HHS5227067.1"
                     /translation="MSYKKIAIITGANSGFGKEFLKLLINEEEITEIWAVARNKARLN
                     QLVDEFGSKVKIFSKDLSKIEEVKEIGTFLSKENVCIKYLINNAGFAKFCSYNDLSID
                     ESINMIDLNISAVVALGLICIPYMQKGSHIMNISSQASFQPLPYQNIYSSTKAFIRNY
                     TRALNVELKSKGINAIAVCPGWMSTNLFKRGIVVAEKGTKNFPGIVSPDIVAKKALKD
                     AKKNKDISVYGINTKSSHLLAKLLPQKMMMKVWLMQQHIKE"
BASE COUNT         1055 a          387 c          346 g         1082 t
ORIGIN      
        1 tgtcagataa atcacttgtg atgttatgtt tgaatgacta gaatttgatt aggatattat
       61 cttaatttgt cagataaatt acttatgatg ttatatttaa atgactagaa tttgattagg
      121 atattatctt aatttgtcag ataaatcaat tataagatta tatactatcc ttatactcta
      181 gttaaatata ttttaatcac taatataaat tagttttttt aacaaaacaa taaaagagta
      241 aagtacaaat aattcctttg tgctctactc tttttaactt tctttagaca atgatataat
      301 gataaatata aaaaattata tattccattc tatagaaata tgctcaccaa taacatgtat
      361 gttgttaatc aatatattat atcaaattat atcaaaatta cataaacctt ataggacaat
      421 catatcttat tacaagaaaa atgtcttatc catattgaat aagtcattca gttcatatac
      481 aaagtcaatt tcattgagaa acatttaata tatgtttata aaaatttcat actattcttt
      541 catatttgca tgtgatataa tttattaact cataattttg ttaatcagtt gtgcttgtat
      601 attatttata taatctaata ttttaagaag gtggtgtaat aactttgaaa ttaaaaattg
      661 ttggtagtgg cggtatgtca attattccaa gttcattttg caaatgcaaa atatgtgaag
      721 aagccagaca aaaaggcgga agatatgaac gattagggcc aagtttatat attgatgata
      781 taaaaatgct gatagacaca cctgaagaca ttgcagtagc ttgtaacaga caaaaaatat
      841 cggaagtaaa acatatttca atttctcacc atgacccaga ccatgttaag ggtattagaa
      901 ttgtcgaaaa aataggatgt gactttatca caggagaaaa taatccaatt ggcttttatg
      961 cgcttcctga agtaattgaa gatataaacc gaacgaatct cgattgtctt aaatattatg
     1021 gtaatgttat aaattgcatt tctattaatg aaacttcgca tgtaaagata aataattttg
     1081 atattgattt gattaacaat aacccagaca ggaatataac cttctatgtt atcaaagaga
     1141 atgaaaaaaa agtcatatat gcctgctgta atcccaagcc atttactcat agtgatatgt
     1201 actttgatgc tgatatttta ataataagtc tagtttctga tgatggtata ttaaatgatg
     1261 gtacaaaact taaagacaca ccatttaaag atgaaatatt tactttagat gagattgttg
     1321 aaattaaaaa ctattataga attaaaaaga ttattgttac acatattgac gaaatgtggg
     1381 gaaaatcata tggttattac agtgaattag aaaagaaact tgataacatt tattttgcat
     1441 atgatggtat ggaaattata gtctaaatca ttaagtaata agcataatgc aaaataagaa
     1501 aacttcaatt taacagtata gttaaactat gtaatatcaa catatcgcag tttttacaaa
     1561 atatcatagt atttatcttt ataaaatttc aagttctaca tattttaata cttcaatatc
     1621 taaataaagt aaaatcaaaa atatatttta tatacattat agacggctta tcggcactag
     1681 ataagccgtt ttgtcacaat tattatttgc tcaacaaaac ttctcataat atataacaga
     1741 ttgaatctcc aactgatact taattaccaa aactcttatt ccttaatatg ttgttgcatt
     1801 aaccaaacct tcatcatcat tttttgtggc aatagttttg ctaataaatg actggatttt
     1861 gtatttatac catacacaga aatatcctta tttttctttg catccttcaa tgcttttttg
     1921 gcaacaatgt ctggagacac tatacctggg aaattttttg tccctttttc agctacaact
     1981 atacctctct taaatagatt tgtactcatc caacctggac atacagcaat tgcatttatc
     2041 cctttactct taagttcaac atttaatgct cttgtataat ttcttataaa cgctttagtt
     2101 gaactataaa tattttgata tggcaatggc tggaatgatg cttgtgaaga aatattcatg
     2161 atatggcttc ccttttgcat atatggaata catataagtc ccaatgctac aacagcacta
     2221 atatttaaat caatcatatt aatagattca tctatactta aatcattgta tgaacagaat
     2281 tttgcaaaac cagcattgtt tataaggtat tttatacata cattttcttt acttaaaaat
     2341 gtaccaattt cttttacttc ttctattttt gataaatctt ttgaaaaaat ttttacctta
     2401 cttccaaatt catctactaa ttgatttaat ctcgccttgt ttcttgcaac tgcccatatt
     2461 tctgttattt cttcttcatt tattaataac tttagaaact ctttaccaaa accactatta
     2521 gcacccgtta taattgcaat cttcttataa ctcataatta ttctccttta ccataagttt
     2581 atacgctcaa actgtaaact tattttttac aaataaaaca ccctctattc agatgttata
     2641 ttcatatcat ttgagatatt atacttatat cattttcaat aattgttata tagcataaaa
     2701 aatagtgtta atattataga atcggtattg attatattta aaaagtagtg ttaattatat
     2761 tatagaatcg gtattgatta tatttaaaaa gtagtgttaa ttatattata gaatcagtat
     2821 tgattatatt ataaaaagta gtgttaaata gaatcgatat tgattatatt
//
LOCUS       DAEORM030000137         2776 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.143, whole genome shotgun sequence.
ACCESSION   DAEORM030000137 DAEORM030000000
VERSION     DAEORM030000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2776)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2776)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 2776)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2776
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.143"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            <1..312
                     /locus_tag="KRH23_003805"
     CDS             <1..312
                     /locus_tag="KRH23_003805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HHS5227068.1"
                     /translation="KFKKAIRELLWFVCEYLKISGNKSYDYKTVQITFNHSMIINEAE
                     KIDMAAKSTGIVSDETIVSNHPWVEDVNDELERLKKQEDTQKEYDDLIPNNQDGVIDE
                     T"
     gene            302..1795
                     /locus_tag="KRH23_003806"
     CDS             302..1795
                     /locus_tag="KRH23_003806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HHS5227069.1"
                     /translation="MKHKDYWRKRFEQLEEAQNNKSVKYYLELEKQYKLAINSIEKDI
                     LAWYNRFAKNEGISLLEAKKLLNTRELEEFKWSVEEYIKYGKENAINQKWMKELENAS
                     ARVHITRLEALKLQIQQQVEVLYGNELDGIDKLMRDIYTSGYYHTAFNVQQGVNVGWS
                     LMSLDTNRINKIISKPWATDGLNFSERIWGKYRPTLVNELHTKLTQSIIRGENPKNLV
                     NDFAKRFNVSKSQAKNLIMTESAFFASASRKDCFSDLDVEKYEIIATLDLRTSNICRE
                     LDGKIFDMKDYQVGITAPPFHCRCRTTTAPWFEDEEGYRAARGEDGKTYYVPSSMKYN
                     EWYEKYVKNNSKQTGAKYTKGDIEWNIRREEEAELYYDNIRNRKDDISKISKNTNWSE
                     KSIGQIKNHIFYNTHIMRDGTRRMLDSDYSMSVAWQRLINGTYEDIDILLLKHEYLES
                     IFEKKYNISNLEAHRMTEKKHDWYKELIKQKGEFEEDDCLNELIRKE"
     gene            1773..2003
                     /locus_tag="KRH23_003807"
     CDS             1773..2003
                     /locus_tag="KRH23_003807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5227070.1"
                     /translation="MNLLEKNNEYVIYSYGYEENKLDGRIKIYLDDFYNYEIIKESKD
                     EHISKSATLKAISKLIKAAKNNDLKKEMSYQC"
     gene            2074..2268
                     /locus_tag="KRH23_003808"
     CDS             2074..2268
                     /locus_tag="KRH23_003808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015981492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5227071.1"
                     /translation="MYILTQVIAVVCVVQIFINCIANVNVGILCNKLKEKNEANIDKV
                     SDEILKRVGEELNKSLDKSL"
     gene            2313..>2776
                     /locus_tag="KRH23_003809"
     CDS             2313..>2776
                     /locus_tag="KRH23_003809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0019069 - viral capsid assembly [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage scaffolding protein"
                     /protein_id="HHS5227072.1"
                     /translation="MDWLKELLEGIKIENNKIDVVSLQKSIEKKIKETTITQEDYTNL
                     ETQLNTANETIKKFEGGMTKEDVENLKTTYETDKKTLEETYKKEIEEKDFNYWLGDAF
                     KSVKCRDEIALKAHLDIEALRNSKDRQKAFEEQINPLKQDKDYLFNATLEGE"
BASE COUNT         1211 a          257 c          503 g          805 t
ORIGIN      
        1 aagtttaaaa aagcaattag agagctttta tggtttgtgt gtgagtattt aaagataagt
       61 ggtaataaga gctatgatta taaaacagtt caaattactt ttaatcactc tatgataata
      121 aatgaagctg aaaagataga tatggcagct aaatcaactg gaattgtatc agatgaaact
      181 attgtttcta accatccttg ggtcgaggat gttaatgacg aacttgagag acttaaaaaa
      241 caggaagata ctcaaaaaga gtatgatgat ttaattccta ataatcaaga tggtgttata
      301 gatgaaacat aaagattatt ggagaaagag atttgaacaa ttagaagaag ctcaaaataa
      361 caaaagtgta aaatattatc ttgaattaga aaagcaatat aaactagcta taaatagtat
      421 agaaaaagat atattagcat ggtacaacag atttgccaaa aatgaaggaa tatctttatt
      481 agaagctaag aaactactaa atacaagaga actagaagag tttaaatgga gtgttgaaga
      541 atatattaaa tatggtaaag aaaatgctat aaatcaaaag tggatgaaag agttagaaaa
      601 tgctagtgca agagttcata taacaaggct tgaagcttta aagttacaaa tacagcaaca
      661 agtagaagtt ttatatggaa atgaacttga tggtattgat aaactaatga gagatattta
      721 tacaagtgga tactatcata cagcttttaa tgttcaacaa ggagtaaacg ttggttggag
      781 tttaatgagt cttgatacta atagaataaa taaaattatc tctaaaccat gggcaacaga
      841 tggattaaat tttagtgaaa gaatttgggg taagtataga cctactttag taaatgaact
      901 acacactaag ctaactcaat caattattag aggtgaaaat ccaaaaaatt tagtaaatga
      961 ctttgctaag agatttaatg tatctaaatc acaagctaag aatttgataa tgactgaatc
     1021 agctttcttt gcatcagcaa gtagaaaaga ttgttttagt gatttagatg tagagaaata
     1081 tgagattatt gctacattag atttaagaac ttcaaatata tgcagagagt tagatggaaa
     1141 aatatttgat atgaaagatt atcaagttgg aataacagct ccaccatttc attgtcgttg
     1201 taggacaaca acagctcctt ggttcgagga tgaagaaggc tatagagcag caagaggaga
     1261 agatggaaaa acatattatg taccatctag tatgaagtat aatgagtggt atgagaagta
     1321 tgttaaaaat aatagtaaac aaactggtgc aaaatatact aaaggtgata tcgagtggaa
     1381 tataagaaga gaagaagaag cagaactata ttacgataat attagaaata gaaaagatga
     1441 tatttccaaa atatcaaaga atacaaattg gtcagaaaaa agtataggtc aaattaaaaa
     1501 tcatattttc tacaatactc atataatgag agatggaact agacgtatgt tggattctga
     1561 ctatagtatg tcagttgctt ggcaaagact tataaatggt acatacgaag atattgatat
     1621 tctcttatta aaacatgaat accttgaaag tatatttgag aaaaagtata atataagtaa
     1681 cttagaagcc catagaatga ctgagaaaaa gcatgattgg tataaagaat taattaaaca
     1741 gaaaggagag tttgaagaag atgattgtct taatgaactt attagaaaag aataatgaat
     1801 atgttatata tagttatgga tatgaagaaa ataagcttga tggaagaata aaaatatatt
     1861 tagatgattt ttataattat gaaataataa aagagtcaaa agatgaacat ataagtaaat
     1921 cagcaacgtt aaaagctatt tctaaactta taaaagctgc taaaaataac gatttgaaaa
     1981 aagaaatgag ttatcaatgt tagaagcact tactgaacaa taaattagta ggtgctttta
     2041 ttatgtaaaa gtttaaaaaa gtaggtgatt ttaatgtata tattaactca agttatagct
     2101 gtagtttgtg tagtacaaat ctttattaat tgtattgcta atgtcaatgt aggtattctt
     2161 tgcaataaat taaaagaaaa aaatgaagct aatatagata aagtttctga tgaaattcta
     2221 aagagagtag gagaagaatt aaataaatca ctagacaaaa gtctttaaag acttttttta
     2281 ttgtgtaaaa aatgaaagga gatatttaaa agatggattg gttaaaagaa ttgctagaag
     2341 gaataaaaat agaaaataac aaaattgatg tagtttctct tcaaaaatct atagaaaaga
     2401 aaataaaaga gactacaatt actcaagaag attatacaaa tcttgaaaca cagcttaata
     2461 cagctaatga aactattaaa aagtttgaag gaggtatgac aaaagaagat gtagagaatc
     2521 taaaaacaac ttatgaaact gataagaaaa ctttggaaga aacttacaaa aaagaaattg
     2581 aagaaaaaga ttttaattac tggttaggtg atgcttttaa atctgttaaa tgtagagatg
     2641 aaatagcatt aaaagctcat ttagatatag aagcactaag aaatagtaaa gacagacaaa
     2701 aagcttttga agagcaaata aatcctttga aacaggataa agattatttg tttaatgcaa
     2761 cactagaagg tgaaga
//
LOCUS       DAEORM030000138         2666 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.144, whole genome shotgun sequence.
ACCESSION   DAEORM030000138 DAEORM030000000
VERSION     DAEORM030000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2666)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2666)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 2666)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2666
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.144"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            311..1909
                     /locus_tag="KRH23_003810"
     CDS             311..1909
                     /locus_tag="KRH23_003810"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative manganese-dependent inorganic
                     diphosphatase"
                     /protein_id="HHS5227073.1"
                     /translation="MSLLVFGHKNPDTDSICSAISLAHLKNKLGIKATAYALGDIRKE
                     AKYALDYFKVDAPEILDNVRIQVRDLNYDKVVPLTPTSSILEAYNLMDEKNVKTLPVT
                     YDDGTFAGIITMKEIAKNLLHQHFTTIHTSLSNICKNLNGTILVDCGEDIKGRVVTLS
                     FGMETLIETLKEGDIAIVGDRYDSIEYAIDTKVKLLILTNHTEISKDLLALAKINGVS
                     VVSVESDNYKTSNVINQCSFLDSIEATENLITFKEDDYMDEIKEIMLETNFRSYPILD
                     DDNKFLGLVSKGHLLNPSKKNVVLVDHNEYAQSADGIEQANIVEIIDHHKLGGISTDV
                     PMSFRVMPVGCNSTIIYQMYKENNVEIPYEIAGLLLSAILSDTLLFKSPTTTDMDKKA
                     CEELSKIAKVDMEKYAMDMFKCGTSLDEYTIEEIVNMDFKEFNMSGHRVGIGQVFTLD
                     IDSIFAKKDEFLSYINSTDYDKLILAVTDIIKEGSYLIYKAEDSLIANAFGVEGVQGT
                     FAPGVVSRKKQLVPNLTTAIKNFK"
     gene            complement(2144..>2666)
                     /locus_tag="KRH23_003811"
     CDS             complement(2144..>2666)
                     /locus_tag="KRH23_003811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="collagen-like exosporium glycoprotein BclA1"
                     /protein_id="HHS5227074.1"
                     /translation="GSIGPTGATGATGVTGPTGPTGATGNSSQPVANFLVNAPSPQTL
                     NNGDAITGWQTIIGNSSSITVDANGTFTVQENGVYYISVSVALQPGSSSINQYSFAIL
                     FPILGGKDLAGLTTEPGGGGVLSGYFAGFLFGGTTFTINNFSSTTVGIRNGQSAGTAA
                     TLTIFRIADTVMT"
BASE COUNT          966 a          352 c          401 g          947 t
ORIGIN      
        1 atatatacaa aattttttac agtataaaat atttataaat ttttagttta ttgacgtatt
       61 aattaatttt ttcccaggta gatttaatca atttatttta aataaaagta aatttgattc
      121 tatgtttgat tgggtaaaag tatatataat aataattttt atattaaatt tgtagtattt
      181 atgtaagaaa taaattttat ataatatttt ttcactaaat ttttttcttt ttacaacaaa
      241 tactcactac cttttgatat aatattttta tcaattatta ttatattcaa gttttgaaag
      301 gagtattaaa atgagtttat tagttttcgg acataaaaat ccagatacag attcaatatg
      361 ttctgcaatt tcattagcac atttaaagaa caaactagga ataaaagcaa cagcttatgc
      421 tttaggagat atcagaaaag aagctaaata tgccttggat tactttaagg tagatgcacc
      481 tgaaatttta gataatgtta gaatacaagt tagagattta aattatgata aagtagtacc
      541 tttaacacca acttcatcta tattagaggc ttataacctt atggatgaaa aaaatgttaa
      601 aacactacct gtaacttatg atgatggaac ttttgctggt atcattacta tgaaagaaat
      661 agctaaaaat ctacttcatc aacactttac aactatacac acatcactat caaacatttg
      721 taaaaacctt aatggtacta ttcttgtgga ctgtggtgaa gatataaagg gtagagtagt
      781 cactttatca tttggaatgg agactcttat agagacttta aaagaaggag acatagctat
      841 tgttggagat agatatgata gtattgaata tgctattgat acaaaagtta aacttttaat
      901 acttactaat catacagaga tttcaaaaga tttgctagct cttgctaaga taaatggagt
      961 gtctgttgtt tctgttgaaa gtgacaatta taaaacttct aatgtaataa atcaatgtag
     1021 tttcttagac tctatagaag ctacagaaaa tttaattaca ttcaaagaag atgattatat
     1081 ggatgaaata aaagagatta tgctagaaac aaacttcaga tcttatccaa tattagatga
     1141 tgataataag tttttaggtt tagtttcaaa aggtcatcta ttaaacccat ctaaaaagaa
     1201 tgttgtttta gttgaccata acgaatatgc tcaaagtgct gatggaattg aacaagcaaa
     1261 catagttgaa ataattgacc atcataaact tggcggtatt tctactgatg ttcctatgtc
     1321 atttagagtt atgcctgttg gatgcaatag tactataatt tatcaaatgt acaaagaaaa
     1381 taatgttgag ataccttatg aaatagctgg gcttctttta tctgctatat tatcagatac
     1441 attattattt aagtctccaa caacaactga tatggataag aaagcttgtg aagaattaag
     1501 taaaatagca aaagtagaca tggaaaaata cgctatggat atgtttaaat gcggtacttc
     1561 tttagatgaa tatactatag aagaaatagt aaatatggat tttaaagaat ttaatatgag
     1621 tgggcataga gttggtattg gacaagtatt taccttagac atagactcta tatttgctaa
     1681 aaaagatgag tttttatctt atataaattc gactgattat gacaaactaa ttcttgcggt
     1741 tacagatata atcaaagaag gttcttattt aatctataaa gcagaagata gcttaattgc
     1801 taacgcattt ggtgttgaag gtgttcaagg tacatttgca ccaggtgttg tatcaagaaa
     1861 aaaacaatta gtccctaatt taactactgc aatcaaaaat tttaaataat ataaaatttt
     1921 taaataacga aaactgtctc aaatctatat ttgagacagt tttttattat atatatattg
     1981 ataataaagt taaataaaaa tccataaatt taaaattttt atgaatatat tttattatta
     2041 ttgttatttt attcattcta aaataggtaa aactcaatat ataaaaatac ttttgtcatt
     2101 taaataaaac ctaaatagtt tttaagatta ttttagacac gttttaagtc ataacagtat
     2161 cagctattct aaatatcgtc aaagtagccg cagttcctgc tgattgccca tttcgtatcc
     2221 ctactgttgt agatgaaaaa ttatttattg taaaagtagt cccaccaaat aaaaaaccag
     2281 caaaatatcc agaaagtact cctccgcctc ctggctcagt agtaagccct gccaaatctt
     2341 ttcctcctaa aattgggaat aggatagcga aagaatattg atttatactt gatgaacctg
     2401 gttgtaatgc tactgaaact gatatataat acacaccatt ttcttgtact gtaaacgtac
     2461 catttgcatc tactgttata cttgaactat ttcctattat tgtttgccaa cctgttatag
     2521 catctccatt atttagtgtt tgtggagatg gtgcatttac gaggaagtta gcaactggct
     2581 gagaggaatt gcctgttgct cctgttggac ctgttgggcc tgttactcct gtcgctcctg
     2641 ttgctcccgt tggtcctata cttcct
//
LOCUS       DAEORM030000139         2463 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.145, whole genome shotgun sequence.
ACCESSION   DAEORM030000139 DAEORM030000000
VERSION     DAEORM030000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2463)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2463)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 2463)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2463
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.145"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            407..580
                     /locus_tag="KRH23_003812"
     CDS             407..580
                     /locus_tag="KRH23_003812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5227075.1"
                     /translation="MATKSILKNVDVRKKAFGRNLVSALENAKNKQEKEVVLSKKCSE
                     VPKDKIKDIFGRF"
     gene            580..1191
                     /locus_tag="KRH23_003813"
     CDS             580..1191
                     /locus_tag="KRH23_003813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HHS5227076.1"
                     /translation="MSGYLIVNLSNMLGELEEEEVKKILSSFSCPLNKDVEEFLKNKA
                     IEFSKQGLASTHLVLTSYKGKPVIVGYFTLANKYFTIKRKTLSNSLARKIVKFGQYNE
                     ELRRYIIGAPLIGQIGKNYSNNYNKLIKGDELLKIACDKIKAVQLDMGGKIVYLECED
                     KPKLIEFYKDNGFVDFGKRSLDKDETDSLDGDYLVQMLKYLKK"
     gene            1268..1456
                     /locus_tag="KRH23_003814"
     CDS             1268..1456
                     /locus_tag="KRH23_003814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5227077.1"
                     /translation="MEIKKNTQDVVSERKNSLDSEFKIPASGVCYMAEFIKESREIIK
                     ELDKHFESCLDVLSKARL"
     gene            complement(1436..1753)
                     /locus_tag="KRH23_003815"
     CDS             complement(1436..1753)
                     /locus_tag="KRH23_003815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5227078.1"
                     /translation="MSKNIDIRNLKQFQKKIERMEQNLKPDFDKIRTIILSKKFMNQH
                     TNFDSFDELLAFGNYIVNSEEDFLAIPDNEFDLFIVKNTDFPDWQTMLDSAYSKYLES
                     CLR"
     gene            1877..2104
                     /locus_tag="KRH23_003816"
     CDS             1877..2104
                     /locus_tag="KRH23_003816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5227079.1"
                     /translation="MGFEISGNLNFDSVIDDLKKEVENNPTIFTSQNVGNKFKEKCKI
                     CEKISEFEILEDGKVKCLECGTEFELNLKVE"
     gene            2174..>2463
                     /locus_tag="KRH23_003817"
     CDS             2174..>2463
                     /locus_tag="KRH23_003817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHS5227080.1"
                     /translation="MQDVKEKVKQDYLKGMKQKEISSKYDISLNTLKSWIKRYNWASE
                     KKKGAPINKRGAPFSNKNSVGHGAPKENKNAEKFGFFSKYLPEETRELIQEIS"
BASE COUNT         1008 a          262 c          412 g          781 t
ORIGIN      
        1 tagtctaagt tcgattctta gaacctgcga cataatatat gtatctccct actaaaaatg
       61 ctaagtttac tccaaactta gcattttaat ttttaaaaag aaaaaagaaa tttttattgt
      121 cataatacta tttgtttagg tatattataa tgtgcatact taaaattaaa tacttagcaa
      181 gcatttgaat taatatacat aagatatatg acataatttt ttatagtgta agttatttaa
      241 attaattata aataacagta attttattat ataaaatgta catattgtga ataataataa
      301 taaaatcatg tacaaaatgc caactgataa ttcctcgaaa tatattgcat atttaacgta
      361 acgtcagtat aattaaatta taatagtgaa gtggaaggtg gtacttatgg ctacaaaaag
      421 tattttaaaa aatgtagatg taagaaaaaa ggcatttgga agaaatctag tatcagctct
      481 agaaaatgct aaaaataaac aagaaaaaga agttgtatta agtaaaaaat gttcagaagt
      541 accaaaagat aaaataaagg atatattcgg gagattttaa tgagtggcta tttaattgta
      601 aacttaagta atatgctagg agagctggag gaagaagaag ttaaaaaaat tctctccagt
      661 ttttcttgtc cccttaataa agatgtagaa gaatttttaa aaaacaaagc tattgaattt
      721 tctaaacagg gtttggctag tacacattta gtgctaactt cttataaagg caagcctgtt
      781 atagttggat atttcactct agctaataag tattttacaa taaaaagaaa aacattatca
      841 aactctttag ctaggaaaat agtgaagttt ggacaataca atgaagaact aagaagatat
      901 attattggag cacctttgat agggcaaata ggaaagaatt attcaaataa ttataataaa
      961 ttaatcaagg gtgatgaact tctaaaaatt gcatgtgaca agataaaagc agtacagtta
     1021 gatatgggtg ggaaaatagt gtaccttgaa tgtgaagata aacctaaatt aattgaattt
     1081 tataaggata atggatttgt agactttgga aaaagaagcc ttgataaaga cgaaacagat
     1141 tcgttagatg gggactattt agttcaaatg ttgaaatatc taaaaaaata aaagtacata
     1201 aaatctaaaa tgactatctt gatagatggt ctttttttat acaataaatt aaaaggagaa
     1261 tgaaattatg gagattaaga aaaacacaca agatgtagta tcagaaagaa aaaattccct
     1321 agattctgaa ttcaagatac ctgcaagtgg tgtgtgttat atggctgagt ttataaagga
     1381 atctagggaa atcataaaag aattagataa acattttgaa agttgtctag atgttttatc
     1441 taaggcaaga ctctaaatat tttgaatatg ctgaatcaag catggtttgc caatctggga
     1501 aatcagtatt tttaactata aataaatcaa attcattatc aggaatagct aaaaagtctt
     1561 cttctgaatt gactatgtaa ttaccaaatg caagtagttc atcaaaagaa tcaaaattag
     1621 tgtgttggtt cataaatttc ttgctaagaa ttattgtgcg aatcttatca aagtcaggtt
     1681 ttaaattttg ttccattctt tcaattttct tttgaaattg ctttaaattt ctaatgtcaa
     1741 tatttttact cataagaaca cctcctttca atagaatatt agcataaaat tgtggtgaat
     1801 tctgctattg tcgaacgatt gttgaaggat attgtataat aacatagaat ttactatact
     1861 ataaggaggt gattatgtgg gatttgagat aagtggtaat ttgaattttg acagtgttat
     1921 tgatgattta aaaaaagaag ttgaaaataa ccctactata tttacatcac aaaatgttgg
     1981 aaataagttc aaagaaaaat gtaaaatatg cgaaaaaata tctgaatttg aaatactaga
     2041 agatggtaaa gttaaatgtt tagaatgtgg gactgaattt gaattgaatc ttaaagtaga
     2101 gtaaacaaaa aaagaatctc aattatgagg ttcttttttt attcccaaaa caaacaaata
     2161 aagaggtggt gatgtgcaag atgtcaaaga aaaggtaaaa caagattact taaaaggaat
     2221 gaaacaaaag gaaatatcat caaagtatga cattagctta aacactttaa agtcatggat
     2281 aaaaagatac aactgggcta gtgaaaaaaa gaagggtgca cctataaata aaagaggtgc
     2341 acccttttct aataaaaatt cagttggtca tggtgctcca aaagagaata agaacgctga
     2401 aaagtttggt ttcttctcaa aatatctacc cgaagaaact agggaattga tacaagaaat
     2461 atc
//
LOCUS       DAEORM030000140         2444 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.146, whole genome shotgun sequence.
ACCESSION   DAEORM030000140 DAEORM030000000
VERSION     DAEORM030000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2444)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2444)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 2444)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2444
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.146"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            256..1557
                     /locus_tag="KRH23_003818"
     CDS             256..1557
                     /locus_tag="KRH23_003818"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006269 - DNA replication, synthesis of
                     primer [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HHS5227081.1"
                     /translation="MGKSKDVEIEKSILGTILLDNKLSYKLDELNENMFMNDICLEIF
                     KIMKELKKENIVIDVATVKSKIDRKSLAIKTSDVTNLITWGQNFGLDGHIKILKENLA
                     RRSINQNCQNLLHSLNLGENIDTCIYKFESNIKEILDKDTYENDDVNSIAGKVLDFLE
                     NKKDIGFKFGIKLLDTTIGGLFKGELTTIAAKSGVGKTALALQIMLNSFKQGKKTLFI
                     SREMTSEQVFMRNICRVTGVSTRNMKSKEIDENDWKLIVNAIGDLSENNLIYINDKID
                     TISAIRKRIRQVKPDLLIVDYVQLLTSQKSMDKREREVATFSRELKNMTLDFNIPVIQ
                     LSQLNNEMKDSRPYGDRPMRDSKAIYHDSNNVVYIHQLKGSDYEEAVRDIGESEEAVR
                     ASEYRGIKMVDLIVAKCRDGQTRHKHFCYFGDKLHFQELNY"
     gene            1633..1908
                     /locus_tag="KRH23_003819"
     CDS             1633..1908
                     /locus_tag="KRH23_003819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mor transcription activator family protein"
                     /protein_id="HHS5227082.1"
                     /translation="MLELRKIIELLEEHKIEVSIPKELHKYSLLEYLELCQQSGGTYF
                     YIKTLEGALKEARNELMIKLFNGKNYMELARMFEMSVINVRHIVRKK"
BASE COUNT         1009 a          193 c          480 g          762 t
ORIGIN      
        1 tatcaagtag tgaattatat tgaacaatat attaataatt ggtagtaaag tatatcaaat
       61 aagatattgc tattatgtag taaattatat aaaacaatgt atcagaataa atagtatatt
      121 aataatttgt agtatatcat gacgaataat acagtcataa caaatagtga gtcataacaa
      181 ataatgtatt tataattgat aatgtattta aaaatcaaaa tataaaaact tataaggaaa
      241 gagagattaa tttatatggg taaatcaaaa gatgttgaaa tagagaagtc tattttaggc
      301 acaattcttt tagacaataa attaagctat aagctagatg aattaaatga aaacatgttt
      361 atgaatgata tatgtcttga gatatttaaa attatgaaag aacttaaaaa agaaaacata
      421 gtgattgatg tggccactgt gaaatcaaag atagatagaa aatctctagc aataaaaaca
      481 agtgatgtga ctaatctaat tacttggggt cagaattttg gtcttgatgg tcatattaaa
      541 attttaaaag aaaatttagc tagaagaagc ataaatcaaa attgccaaaa ccttttacac
      601 agcctaaacc ttggagaaaa tatcgatact tgtatttaca aatttgaaag taatataaag
      661 gagattttgg acaaggatac ttatgaaaat gatgatgtaa atagtatagc agggaaggtg
      721 cttgattttt tagaaaacaa aaaagatatt ggatttaaat ttggtataaa attacttgat
      781 accactatag gaggtctttt taaaggagag ctaaccacaa tagcagctaa atcgggggtt
      841 gggaagactg ctttggcact tcaaataatg ttaaattcat ttaagcaagg taaaaaaact
      901 ttatttataa gtagagaaat gaccagtgag caagtattta tgagaaatat atgcagagta
      961 actggtgtaa gtacaaggaa tatgaaatct aaagaaatag atgaaaatga ttggaaactt
     1021 attgtaaatg ctataggtga tttaagcgaa aataacttaa tttatattaa tgataagata
     1081 gatacaatta gtgcaattag aaagaggata aggcaggtaa agccagattt attaatagtg
     1141 gattatgtgc aactccttac atctcagaaa agcatggata agagagaaag ggaagtagct
     1201 actttttcga gagaacttaa aaatatgact ttagatttta atatacctgt aatccaatta
     1261 agtcagttaa ataatgaaat gaaagattca agaccttatg gagatagacc tatgagggat
     1321 agcaaagcca tctaccacga tagcaacaat gtggtttata tacatcaatt aaaggggagt
     1381 gattatgaag aagcagtgag agatattgga gaaagtgagg aggcagttag agcatcagaa
     1441 tacaggggaa ttaagatggt tgatttaata gttgcgaagt gtagagatgg acagactagg
     1501 cataagcatt tttgttactt tggggataag ttacattttc aagaactaaa ttattaggtc
     1561 aataaagtag taataacaag cttattaaaa gtcgggaaat agcaaataga ttataaaata
     1621 tgaggtgaaa atatgttgga attaagaaaa attatagaat tacttgaaga acacaagata
     1681 gaagtaagta ttccaaagga gttacataag tatagtttat tggaatacct tgaattgtgt
     1741 caacaaagtg ggggaacata tttttatatt aaaacactgg aaggggcttt aaaagaggct
     1801 agaaatgagc ttatgattaa attgtttaat gggaaaaatt atatggaatt agcgaggatg
     1861 tttgaaatga gtgttattaa tgtcaggcat attgttagaa aaaaatagat atttttggag
     1921 aatacaagtg tgatatactt ctgaaataga agttattata gttgaaataa aattgtggtt
     1981 aataaattaa agttgtgtat aagtttaaga ttatagagga gtataagtgt gattaacagc
     2041 atgattttgt gaataaaatt gaggatatat atgagttaaa tgtgtgatta ataaggtaag
     2101 gttgtgtata agattatgag tatttaaaag gaggggctat aattaatagt gtagagttgt
     2161 gtgtttgctt aagattatat aataatttaa tagattaaac tatactaata aggtaaaatc
     2221 gtgtgtttag ttaaagctta ttataaaatc ttgatatgtg aataaagtta agattataat
     2281 agatttaacc tgtggctaat agaataaaat tgtgaataaa gttaagatta taataggttt
     2341 aatctgtgac taatagagta agagtgtaaa tagagataaa cttcaatatg agcttaactt
     2401 gtggttaata gagtaaggtg taaatagaga taaacttcaa tatg
//
LOCUS       DAEORM030000141         2313 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.147, whole genome shotgun sequence.
ACCESSION   DAEORM030000141 DAEORM030000000
VERSION     DAEORM030000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2313)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2313)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 2313)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2313
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.147"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            <1..1647
                     /locus_tag="KRH23_003820"
     CDS             <1..1647
                     /locus_tag="KRH23_003820"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008745 - N-acetylmuramoyl-L-alanine
                     amidase activity [Evidence IEA];
                     GO_process: GO:0009253 - peptidoglycan catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HHS5227083.1"
                     /translation="KQELEKMGLNLKDYNVTQECIIEDITSRKDVNKYLRKTSAPITE
                     LTGSDRYETAVKISKEGWKNGSDKVVIINGDVSIDGIISTPLATTYNAPILLVEKNNV
                     PNSVKSELKRLNPRDVIIIGDENAISKTTANQIKSTVNASQTRLKGSNRYETSLLIAK
                     EIDKNHDVEKVYITNANGGEVDALTIAAKAGQDKQPIILTDKNSITDNTYKWLKSEDL
                     QNAYFIGGPQMISTNVINKVNDITKDNVTNNRVYGADRHETNANVIKKFYTDDELEAV
                     LVAKSDVLVDALAAGPLAANLKSPILITPKTYVSAYHKDNLEAKSANKVYKIGGGLTS
                     KVMNSIASSLSKHNTTPTEPGNSGGKTVMIDPGHGGSDTGTTGKPLGGIKEKDYTLNT
                     SLATTEYLRSKGFNVIMTRDTDKTLSLGNRTALSNSLRPDLFTSIHYNASDTTGNGVE
                     VFYKLKDKDGGTTKTVATNILNRILEKFNLKNRGAKTRTLSTDPTKDYLYVLRNNDMP
                     AVLVECAFLDNEKDMSLLNTSNKVKEMGTQIGKGIEDSLK"
BASE COUNT          954 a          267 c          392 g          700 t
ORIGIN      
        1 aaacaagaac tagaaaagat gggattaaat ttaaaagact ataatgtaac gcaggaatgt
       61 ataattgaag atataacttc tagaaaagat gtaaataaat atttaagaaa aacttctgca
      121 cctattacag aacttacagg aagtgataga tacgaaacag cagttaaaat aagtaaagaa
      181 ggctggaaaa atggttcaga taaggtagtt ataataaatg gggatgtaag tatagatggc
      241 attatatcaa ctccactagc aactacatat aatgcgccaa tacttttggt tgaaaaaaac
      301 aatgtaccta atagtgtaaa atcagaatta aagcgtttaa atcctagaga tgtaattata
      361 attggagatg agaatgctat ttctaaaact actgctaatc aaattaaatc gactgtaaat
      421 gctagtcaaa cacgtctaaa gggctctaat agatatgaga catctttatt gatagcaaag
      481 gaaatagata aaaatcatga tgtggaaaaa gtgtacataa caaatgctaa tggtggagaa
      541 gtggatgcac ttactatagc agcaaaagca ggtcaagaca agcaaccaat tatattaact
      601 gataaaaata gtattacaga caacacatat aaatggttaa agagtgagga tttacaaaat
      661 gcttatttta taggtggccc tcaaatgata tcaacaaatg ttataaataa ggtaaatgat
      721 ataactaaag ataatgttac taataataga gtatatggag cagatagaca cgaaacaaat
      781 gcaaacgtaa taaaaaaatt ctatacagat gatgagctag aggctgtttt agtagctaaa
      841 tcagatgtac ttgttgatgc tttagcagca ggtccattgg ctgccaactt aaaatctcca
      901 atacttataa caccaaagac gtatgtatct gcataccata aagataattt agaagctaaa
      961 tcagctaata aagtatataa aataggagga ggattgactt ctaaggtaat gaactctata
     1021 gcatcatcat tatctaaaca caatacaact ccaacagaac caggaaatag tgggggtaag
     1081 acagttatga ttgacccagg acatggtggt tcggacactg gaacaacagg taaaccatta
     1141 gggggtatta aagaaaaaga ctatacatta aatacttcac ttgcgacaac tgaatattta
     1201 cgttcaaagg gattcaatgt aataatgaca agagatacag ataagacttt atctcttgga
     1261 aatagaactg ctttatctaa ctctttgaga ccagatttat ttacgagcat acactataat
     1321 gcatctgata caactgggaa tggtgtagaa gtattttata agcttaaaga taaagatgga
     1381 ggaactacta agactgtagc tacaaatata ttaaatagaa ttttagagaa atttaatcta
     1441 aaaaatagag gtgcaaaaac aagaacacta tcaactgacc ctacaaaaga ttatttatat
     1501 gttttaagaa ataatgatat gccagctgta cttgtagaat gtgcattttt ggataatgag
     1561 aaagatatga gtttacttaa tacatcaaat aaagtaaaag aaatgggtac acaaataggt
     1621 aaaggcatag aagattcatt aaaatagtct acaatgagag catagaaaaa tttaaaataa
     1681 attaatctgc aattttaaat ttagactaaa gctataagat aagaatgtaa ttataatagt
     1741 aataaagact gtatatacat tgtgcatata agtgcgaaat gaggtatata cagtcttttt
     1801 atgattaatt gtaaaaggat ttatattata tgaagaattt acatatctta aggctacagt
     1861 taattgtcaa gagttggagt attcatttgt aatacacaat aaaagcttaa ttactatatt
     1921 ttattgtgtg tttgtgtgtt ttttgtggat ttttatgtca ataaatgata tagtatagat
     1981 aattaaatgt attaaatata tttaattttt ttattttttg tttttataat ttttttagaa
     2041 gtttattttt tatgtactta tttataattt tgggtaaaaa cactttgata taatttcaaa
     2101 aattaaaagg ttaaaaaaca aagtagaaat ttatgttaaa taaggagatt aatatgagaa
     2161 gaaatacaaa attattaaca acaggtattc tttcaatggc aatcgtcgca cctacaatgg
     2221 catttgctac tgaatctaat gctatggaaa ataacgctga tttaaatata aacttagaga
     2281 aaaaaagtat cgttttaggt agtacctcaa aag
//
LOCUS       DAEORM030000142         2176 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.148, whole genome shotgun sequence.
ACCESSION   DAEORM030000142 DAEORM030000000
VERSION     DAEORM030000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2176)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2176)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 2176)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2176
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.148"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            complement(<1..534)
                     /locus_tag="KRH23_003821"
     CDS             complement(<1..534)
                     /locus_tag="KRH23_003821"
                     /EC_number="2.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003886 - DNA
                     (cytosine-5-)-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HHS5227084.1"
                     /translation="MLTFLDLFAGIGGFRLGMEKAGHKCLGHCEYDKFANLSYNAMHK
                     PKEDEWFERDIREIRTENIPRADVWCFGFPCQDISVAGKQFGFRGERSSLFFTVTKLI
                     RELKEEDRPKYLLIENVKNLLSVNGGFDFLKVLVELDEIGYDAEWQVLNSKNFGVPQN
                     RERIFIVGHFRGRSTRKV"
     gene            complement(642..977)
                     /locus_tag="KRH23_003822"
     CDS             complement(642..977)
                     /locus_tag="KRH23_003822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5227085.1"
                     /translation="MNILASVILVIGSFIAGRVYEYRLNLNENDEADSKVLLDVFNEI
                     SVLREENKSLKEKLQEKELLFINRLIDFLHDKKICECCIYDCKIDDIEYDCEDGIKKW
                     LDSEELIFE"
     gene            complement(961..1095)
                     /locus_tag="KRH23_003823"
     CDS             complement(961..1095)
                     /locus_tag="KRH23_003823"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5227086.1"
                     /translation="MEVSRTEYTIKRAKELYDNGEDIFIAIDKAREEYEEMVKSEYLS
                     "
     gene            complement(1095..1460)
                     /locus_tag="KRH23_003824"
     CDS             complement(1095..1460)
                     /locus_tag="KRH23_003824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5227087.1"
                     /translation="MLKVERYFSGSVADNIFEDDLTLRNYLALYCCIYGVNKNGELVF
                     PTRGKMLIEFNVDRDRKKRKKASKVKLINVKTGEEKIFDSIDSAACFLRLQSQAVYQT
                     IKKKTKTRSGWKAEYIEEE"
     gene            complement(1474..1992)
                     /locus_tag="KRH23_003825"
     CDS             complement(1474..1992)
                     /locus_tag="KRH23_003825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5227088.1"
                     /translation="MEEEYRKFFLERNGEKIEMVQNCEGAIKISLNNIKTDNSHRPWN
                     LKAEGTATVTLYLGKLLFEEMLWLKILYLLEVIAEKMMMGVLGMIIIRSQNKLDLMRV
                     NRVEIDSRYVYAVFEGESNVREIGRYKSEERAIEVLNRIQEAIIAGTKFDIINKDGVR
                     CNKEKVFEMPVE"
BASE COUNT          642 a          471 c          199 g          864 t
ORIGIN      
        1 tacttttcgt gtacttcgtc ctctaaaatg tccaacaatg aatattcgtt ctctattttg
       61 gggtactccg aagtttttag aattaagaac ttgccactct gcatcatagc cgatttcatc
      121 cagttcaacg agaactttga ggaaatcaaa tcctccatta acactaagta gatttttaac
      181 gttttcaata agtaaatact tgggtctatc ttcttctttg agttctctaa taagttttgt
      241 aactgtaaaa aataaacttg aacgttctcc tctgaatcca aattgtttcc ctgcaacaga
      301 aatgtcttga catgggaatc caaaacacca gacatctgct cttgggatat tttctgttct
      361 aatttctcta atatctcttt caaaccattc atcctccttc ggtttgtgca tggcattata
      421 acttaaattt gcgaatttat catattcgca atgtcccaaa catttatgtc ctgctttttc
      481 catccctagc ctaaagccac ctatccctgc gaataaatct aaaaatgtaa gcaatacaac
      541 gcctccttat tttcattttt gagagttaca aaacatctca atgataattt tattaaaaaa
      601 cattttgcaa ctctctaaac tgttttaatt agatatttct tctattcaaa tataagttct
      661 tcgctatcaa gccacttttt aataccatct tcacaatcat attcaatatc atcaatctta
      721 cagtcataaa tacaacattc gcatatcttt ttatcatgta aaaaatctat taatctattg
      781 atgaatagta actctttctc ttgtaacttt tctttaagac ttttattttc ttctcttaac
      841 acactaattt cattaaaaac atctaaaagt acttttgaat cagcttcatc attttcattt
      901 aaattcaatc tatactcata aactctacca gctataaaac ttcctattac taatatcaca
      961 ctagctaaga tattcacttt taaccatctc ctcatattct tctctagcct tatctatagc
     1021 aataaatata tcctctccat tatcatataa ctcttttgct cttttaattg tgtattcagt
     1081 ccttgaaact tccattattc ctcctcaata tattcagctt tccagccact tcttgtttta
     1141 gttttctttt taattgtttg gtaaactgcc tgactctgta gtcttaaaaa acatgctgca
     1201 ctatctatag aatcaaatat tttttcttca ccagttttga cattaattaa ctttactttt
     1261 gaagctttct ttctcttttt tctatcccta tcaacattaa actctattag catttttcca
     1321 cgtgttggaa atacaagttc tccatttttg tttactccat agatacagca atatagtgct
     1381 aaataatttc taagagtcaa atcatcttca aatatattat ctgcaacaga accactaaaa
     1441 tatctttcaa cctttaacat ttcagccccc tccttattca actggcattt caaacacttt
     1501 ttctttgttg catctaaccc cgtctttatt tataatgtca aacttagttc ctgcaataat
     1561 agcctcctgt attctgttta atacttcaat agctctttct tctgatttat acctacctat
     1621 ttctctaaca tttgattcac cttcaaacac tgcatataca tatctactat ctatttcaac
     1681 tctattaact ctcattaaat ctaatttatt ttgacttcta attattatca ttcctaatac
     1741 ccccatcatc attttttctg ctataacttc taataaatac aatattttaa gccacagcat
     1801 ttcttcaaaa agcagtttac ctagatatag cgtcactgta gctgttcctt ctgcctttaa
     1861 attccaaggt ctatgcgaat tatctgtttt tatattattt aagcttattt ttattgctcc
     1921 ttcgcaattt tgtaccatct caattttctc accattacgc tctaaaaaaa attttctata
     1981 ctcttcttcc attttccatc cctccaatat tttaactcct aggaagtaat attgcataat
     2041 tactccctag attatttaac ttaattaaaa aggtatatcg tcatcatcta ttgcttgaaa
     2101 accttgtggg tccagtcctg gtggtatata ttcctgttgc tctttatgat tattactatc
     2161 acttttacta gaaagt
//
LOCUS       DAEORM030000143         2157 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.149, whole genome shotgun sequence.
ACCESSION   DAEORM030000143 DAEORM030000000
VERSION     DAEORM030000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2157)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2157)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 2157)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2157
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.149"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            <1..941
                     /locus_tag="KRH23_003826"
     CDS             <1..941
                     /locus_tag="KRH23_003826"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5227089.1"
                     /translation="IRQESISNMQKKIDDKVDEVDNKIVEVNTAKTDMTTTVSNKITE
                     FEKRFNELENLDTAGEILQSKETTDGQIKDTLKERLTYDFNKLDLKIEQLIAGGINVA
                     FNKTYDTSEWIEVDGGFELSVEHKLVTQKILVSSIDKLNRKSLITSYKIMDDNNIILF
                     NEVAIDIEVTVVNGGSAIELIKFTINDDIESLESSYSSIETKRLLDKKANLEHTHDIY
                     VEKVEGKELSTEDYTTEEKVKLSQLDTYKNKETKFNTNGSIIEILDNNIKYITKFNTN
                     GSISKEKYINDILINTTITNFKNGMIEETVTNEGVI"
     gene            941..>2157
                     /locus_tag="KRH23_003827"
     CDS             941..>2157
                     /locus_tag="KRH23_003827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016040100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HHS5227090.1"
                     /translation="MSWAEVYKINSDIQGEPLNFLNYLQDLKLNGSESYLLYEGNHRI
                     WEELYLNSLYLFSDRGIREAVYTAFSETDIDNLFDKSTKLGEQLNAFYRTDIFSLGNA
                     DNVVKGMTVEHYNSLEEKFKAGYDRYVTREQEKSTIGAWFNSTFSLDNTDLENLTTIE
                     EILANVEATNAILNNSNAIVALTMCKTSMDAVVASSNAMDLLGQYILKVTAEPAVIKA
                     ILENNVIREAIINSIEAMTHISTNHESVRMIFENLEATQLLLANQDTLDLVLANTNVI
                     RLVLTKILETHNSIFKLDINTLITNMTSMVNSTNIEYQDKIFPIVENMNTNFISIKDL
                     LSNNNLDKKNIIAIFQCIENNLSVITALSSDEVAFNSIKEIDLAIAKTAAKLAGIDNI
                     NINTSDALARSDK"
BASE COUNT          922 a          214 c          352 g          669 t
ORIGIN      
        1 taatcagaca agaatctata agtaatatgc agaaaaaaat agatgataaa gtagatgagg
       61 ttgataacaa aatagttgaa gtaaatactg ctaagacaga tatgacaaca actgttagca
      121 ataaaataac tgagtttgaa aaaagattca atgagttaga aaatttagat acagcaggag
      181 aaatattaca atcaaaagaa acaacagatg gtcagataaa agatacttta aaagagagat
      241 taacttatga tttcaataaa ctagatttaa aaatagagca acttattgct ggtggaataa
      301 atgtagcatt taataaaaca tatgatacat ctgaatggat tgaagttgat ggaggatttg
      361 aactttcagt agaacataaa cttgttactc aaaaaatatt agtctcttca atagataaac
      421 ttaatagaaa aagtttgatt acatcttata aaattatgga tgacaataat ataatactgt
      481 ttaatgaagt tgctatagac attgaagtta cagtagttaa tggtggttct gctattgaac
      541 ttataaaatt tactattaat gatgatatag agtctcttga aagttcttat tctagtatag
      601 agacaaaaag actattagat aaaaaagcta atttagaaca tactcatgat atatatgttg
      661 agaaagttga aggcaaagaa ctctctacag aagattatac aactgaagaa aaagtaaaac
      721 tttctcaatt agatacttat aaaaataaag aaacaaaatt taatacaaat ggttctataa
      781 tagaaatatt agataataat atcaagtata ttacaaagtt taatactaat ggttctatat
      841 caaaagaaaa gtatataaat gatatattaa taaatacaac aataactaac tttaaaaatg
      901 gaatgataga agaaactgtt acaaatgaag gggtgattta gtgagttggg cagaggttta
      961 taaaataaat agtgatattc aaggagaacc tttaaatttt ttaaattatt tacaagattt
     1021 gaagttaaat ggttctgaaa gttatctttt atatgaaggt aatcatagga tttgggaaga
     1081 actgtactta aatagtttat atttattttc tgatagagga attagagaag ctgtgtatac
     1141 agctttttca gaaacagaca ttgataatct gtttgataaa agtactaagc taggggaaca
     1201 attaaatgcc ttttacagaa cagatatatt tagtttagga aatgctgata atgtagtaaa
     1261 aggaatgact gtagagcatt ataattcgtt agaggaaaaa tttaaagcag ggtatgatag
     1321 atatgttaca agagaacaag aaaagtcaac tataggagca tggtttaatt ctacttttag
     1381 cttagataat actgatttag aaaatcttac aacgatagaa gaaatattag caaatgtgga
     1441 agctactaat gcaatactta ataatagtaa tgcaatagta gctttaacta tgtgcaaaac
     1501 aagtatggat gcagttgtag caagttcaaa cgcaatggat ttgctaggac aatatatttt
     1561 aaaagttaca gcagaaccag ctgttataaa agcgatttta gaaaataatg taattagaga
     1621 agctataata aatagtattg aagcaatgac tcatatatca acaaatcatg aatcagttag
     1681 aatgatattt gagaatttag aagctacaca gctactatta gctaatcaag atacattaga
     1741 tttagtttta gcaaatacaa atgttattag acttgtactt acaaagattt tagaaactca
     1801 taatagtata tttaagttag atataaatac tttgataaca aatatgacta gtatggttaa
     1861 ttcaactaat atagaatatc aagataagat ttttcctata gttgaaaata tgaatactaa
     1921 ttttataagt ataaaagatt tattatcaaa taataactta gacaaaaaaa atataattgc
     1981 tatatttcaa tgcatagaaa ataatttaag tgttataaca gctttatcaa gtgacgaagt
     2041 agctttcaat tctatcaagg aaattgattt agctatagca aaaaccgcag cgaagctagc
     2101 ggggatagac aatataaata tcaacacttc ggatgcgtta gctagaagtg ataaata
//
LOCUS       DAEORM030000144         2131 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.150, whole genome shotgun sequence.
ACCESSION   DAEORM030000144 DAEORM030000000
VERSION     DAEORM030000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2131)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2131)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 2131)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2131
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.150"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            complement(37..1254)
                     /locus_tag="KRH23_003828"
     CDS             complement(37..1254)
                     /locus_tag="KRH23_003828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallo-hydrolase"
                     /protein_id="HHS5227091.1"
                     /translation="MLGKKCMDYLQTLGKISSTTNGLTRLILTQEHKKSIDLISSWME
                     GLNLDIEIDDIGNVIGTYKSSFPNAPTLVVASHQDSVKCGGIFDGMLGIIVPLVGLEE
                     AKHNNRSYPFNIKLIAFAEEEGTRFETSLMGSKVFAGTFKEELLKSVDENGITLEEAV
                     TKFGFNTKNLTNLHPRKDVDAYLEFHIEQGPVLENESLPAGIVSSITGFKSFKISVNG
                     KSGHAGTLPMNMRLDAGCCACECVLAIEKVAKTTADLVATVGKMNFYPSSSNVVPERA
                     EFTLDVRSCSQEILDNSVEKIFNEISHICENRKLNYTSELAFENVPVPCSNKITKIIE
                     KSFIDLNLNPFYIYSGAGHDAQEMDNITDIGMVFIRCAGGVSHNPNESVSVDDLDTAV
                     KIFLKILDNLDLK"
     gene            complement(1445..1858)
                     /locus_tag="KRH23_003829"
     CDS             complement(1445..1858)
                     /locus_tag="KRH23_003829"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HHS5227092.1"
                     /translation="MELEITEKIEKQDEDTIFQGLLKYNLARLEDKNPVDLGIYIRDK
                     AGKIVAGFIGVTHGNWLSIKYLWVSEKLRYKGTGSQLLYKAEKIAKERGCKYVFLDTF
                     SFQAPKFYEKFGYHKVFSLENYPLTGKRYYFRKIL"
BASE COUNT          750 a          333 c          235 g          813 t
ORIGIN      
        1 agattatata ttttaatata ctttcttata taagaattat tttaaatcaa gattatctag
       61 tatttttaaa aatattttta cagcagtatc caagtcatct acagaaacac tttcattagg
      121 attatgactt acgcccccag cgcatcttat aaataccata ccaatatcag ttatattatc
      181 catttcctga gcatcatggc cagcaccact ataaatataa aaaggattaa gatttaaatc
      241 tataaaactt ttttctatga tttttgttat tttattagaa catggtacag gaacattttc
      301 aaaagcaagt tcacttgtat aattaagttt tctattttca catatatgtg atatttcatt
      361 aaatatcttt tctacagaat tatcaagaat ttcttgtgaa caagagcgta catcaagagt
      421 aaattcagct ctttcaggta ccacatttga tgaagatgga tagaaattca tctttcctac
      481 agtagcaacc aaatcagcag tcgttttagc tactttttcg atagctaata cacattcaca
      541 ggcacaacat ccagcatcaa gtctcatatt cattggaagt gtaccagcat gtccagactt
      601 accatttact gatatcttaa aacttttaaa tcctgtaata cttgatacaa ttccagcagg
      661 aagagattca ttttctaaaa caggaccctg ctcaatatga aattctaaat atgcatctac
      721 atcttttcta ggatgcaaat ttgttaagtt ttttgtatta aatccaaact ttgttacagc
      781 ttcttcaagt gtaattccat tttcatcaac agatttaaga agttcctctt taaaagtacc
      841 agcaaaaact ttacttccca ttaaagaagt ttcaaatcta gttccttcct cttcagcgaa
      901 agcaattagc ttaatattga aaggataaga cctattattg tgttttgctt cttcaagacc
      961 aactagaggc actattatac ctaacatacc atcaaatata cctccacact ttacactatc
     1021 ttgatgagat gcaactacta atgtgggagc atttggaaag cttgatttat atgtacctat
     1081 aacgtttcca atgtcatcaa tttcaatatc aagatttaaa ccttccatcc atgaactaat
     1141 taaatcaata gattttttat gttcttgagt caagataagt cttgtaagac catttgttgt
     1201 tgaacttatt tttcctaatg tttgtagata atccatacat ttttttccta acatatttac
     1261 ctcctaaaaa tataattttt atttaagcta agattagctt ttatacttat aatttttgaa
     1321 ctttcaaata attttgtatg tatagtaaaa tactatttta gtattaataa tgatataaaa
     1381 atataaagtc tgtagacgaa gagcagaagt tttaagttaa aaatataaaa tatgattttt
     1441 attattatag tatttttcta aaataatatc tctttccagt tagaggataa ttttcaagtg
     1501 aaaatacttt atggtatcca aatttctcat aaaatttagg tgcttgaaaa ctgaatgtat
     1561 ctaaaaaaac atatttacaa cctcgttctt tagcaatttt ttcagcctta tataaaagtt
     1621 gacttccagt acctttatat ctaagcttct cactaaccca taagtatttt atagaaagcc
     1681 aattaccatg agtaacacct ataaaacctg caacaatttt acctgcttta tctcgaatat
     1741 atattcctaa atccactggg tttttatctt caagtctagc aagattatat tttaataatc
     1801 cttgaaaaat agtatcttca tcttgttttt ctattttttc tgtaatttct aattccatat
     1861 ttgaactttc tccttgtata atcttttgta tattggtatt ttttaataaa atcagtagaa
     1921 agaatatagt ttaacattat tctaataggc atttatgcta atgtcaaact aataatactt
     1981 attcttaatt ttatattgtt gatattaaat ttttttaaat aaaaatgtag tttaagttat
     2041 ataaaaagaa atcatcaata aatttagtaa acctaaattg ttgaatatta aaataagtta
     2101 atttaataca taaaaactat tttagatgtt a
//
LOCUS       DAEORM030000145         2058 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.151, whole genome shotgun sequence.
ACCESSION   DAEORM030000145 DAEORM030000000
VERSION     DAEORM030000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2058)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2058)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 2058)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2058
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.151"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            197..454
                     /locus_tag="KRH23_003830"
     CDS             197..454
                     /locus_tag="KRH23_003830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5227093.1"
                     /translation="MIIIRSQDKTNLMQINQIKIDGSQVYAVFESKIDTVKIGDYENN
                     TRAIQVLDNIQNFIENGTKYDYITSNKVRYNVNKIFQMPAK"
     gene            complement(564..1244)
                     /locus_tag="KRH23_003831"
     CDS             complement(564..1244)
                     /locus_tag="KRH23_003831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA];
                     GO_process: GO:0046677 - response to antibiotic [Evidence
                     IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HHS5227094.1"
                     /translation="MIWTFYSFICVILPCLIYQIVVIKRKNLKVEKNVMIHLVWVYIF
                     LLYIYLALSKAGIGSIWDIGRYSGLFRIDEINLIPFDSVGILTYILNIIMFMPLGFLL
                     PLIWKNFRNIINVSLTGLGFSLAIELCQLFNLRATDIDDLMMNTLGAVLGYFIWVGVN
                     NLFNLIKKKDIFPSIYKNIIQDEIAITIDDDISKKITSLYKNEAIIYLILAVLGEFLL
                     FNWSIIPY"
     gene            1503..1802
                     /locus_tag="KRH23_003832"
     CDS             1503..1802
                     /locus_tag="KRH23_003832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5227095.1"
                     /translation="MKWIKWYSITCICIFIVVAFYMFIFPNKIETIDTSSAYSFVEKK
                     VPNSAVYQGYKKNPVDGTTTIYYSYDNSTHIVRLSHPEDYSRKINWDKVSNIRFD"
BASE COUNT          854 a          221 c          231 g          752 t
ORIGIN      
        1 aatgcaatct acaaataaaa caaagtatta tcaaaaaagt attctttaag aaaatttttt
       61 attagagatg taattgatat aaataatcgt attaaaaaat gaaatactaa gtttaaaaat
      121 ttaaataatc tataaatcaa ttataaaata ttatttatta gaaattaaaa tgaattaagt
      181 aaatggagga attgatatga taataattag aagtcaagat aaaactaatt taatgcagat
      241 aaaccaaatt aaaatagatg gtagtcaagt ttatgcagta tttgaaagta aaattgatac
      301 tgtaaaaata ggagattatg aaaataatac aagagctata caagtgttgg acaatataca
      361 aaacttcatt gaaaatggaa caaaatatga ttatataaca tcaaataaag tcagatacaa
      421 tgttaataaa atatttcaga tgccagctaa atagtgagtg tgcattttag tttaataact
      481 aaagcccact ttcttttgta gtatgaaaga gggctttaca tatttgtaaa tatcgaagta
      541 cacttatttt atcaataaat tatttaataa ggtataatgg accaattaaa caataaaaat
      601 tctcctaaaa cagcaagtat taaatatata atagcttcat ttttgtaaag agaggtaatt
      661 tttttgctta tgtcatcatc aattgtaata gcaatctcat cttgaataat atttttatat
      721 atagatggga aaatatcttt tttctttata agattaaata aattatttac acctacccat
      781 ataaaatatc ctaaaacagc acctaatgtg ttcatcatta aatcatcaat atctgtagct
      841 cttaagttaa acaattgaca aagttcaatt gctaatgaaa aacctaatcc agttaatgaa
      901 acattgataa tatttctaaa atttttccaa attaaaggta gtaaaaatcc taaaggcata
      961 aacataatta tatttaaaat atatgttaag atgccaactg agtcaaaagg tattagattt
     1021 atttcatcaa ttctaaaaag cccactatac cttcctatat cccatatgct accaattcca
     1081 gctttactaa gtgctagata gatatataat aaaaaaatat atacccatac taaatgtatc
     1141 attacattct tttcaacttt caaatttttt cgttttataa cgactatttg gtatattaag
     1201 catggtaata taacgcaaat aaatgaataa aatgtccata tcattttatt ttgtcccctt
     1261 tcaaatttat gtttttagtt ttataagtac tatctttata ttaaactgta agttttaaaa
     1321 atcttttaat aaaatcttaa aaatttatta atttataaaa atatattatt aagattaaaa
     1381 atatatataa tcaaagtttc tacaattata tagttaggta tataaaaatt ttatcgtatg
     1441 cataaatatt ataaatatat ggaaataata atagtatatt ttggtaaagt aggaggaatt
     1501 ttatgaaatg gattaaatgg tatagtatta catgcatatg tatttttata gtagtagctt
     1561 tttatatgtt tatatttcct aataaaatag aaactattga tacttcatct gcatatagct
     1621 ttgttgaaaa gaaagtacca aatagtgctg tgtatcaagg atacaaaaag aatccagttg
     1681 atggtactac tacaatttat tacagctatg ataattcaac tcatatagtc agattatcac
     1741 atccagaaga ctattcaagg aagattaatt gggataaagt ttcaaacatc agatttgatt
     1801 aatctttaat atttataaaa gtctatatat ctaaggcaaa tatattatta atcttattca
     1861 tagttgagca ctttctatta tagaagtgcc tcttctgatt tatatcataa aatattactc
     1921 aacaatttgt aaaatatatt agtttataaa atatattgaa aagataatat tatataatac
     1981 gattgtgtaa gatattgata aaaaatcgta ataaattttc attagtatat gctaatattt
     2041 ttttacaatt ttcgtaat
//
LOCUS       DAEORM030000146         1866 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.152, whole genome shotgun sequence.
ACCESSION   DAEORM030000146 DAEORM030000000
VERSION     DAEORM030000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1866)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1866)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 1866)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1866
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.152"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            <1..399
                     /locus_tag="KRH23_003833"
     CDS             <1..399
                     /locus_tag="KRH23_003833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain-containing protein"
                     /protein_id="HHS5227096.1"
                     /translation="IKKYFEKYIGVITPNNFIELMSYLDDGMEADVIIRAVDEAVGSG
                     VKNYKYVKTILNNWIEAGVKTVLELTEYQNEFERKKKSKQEKKQSNSKTVNTHNVNKN
                     KFANFNQTFTQYEEKELDEIIKKSQKEKFK"
     gene            460..633
                     /locus_tag="KRH23_003834"
     CDS             460..633
                     /locus_tag="KRH23_003834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="resolvase"
                     /protein_id="HHS5227097.1"
                     /translation="MARIYAQRSGSLNEQDRLELLRLLGKAGYTVKVAREKQNSKTTY
                     TYFVEYTEEQEEK"
     gene            649..1056
                     /locus_tag="KRH23_003835"
     CDS             649..1056
                     /locus_tag="KRH23_003835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HHS5227098.1"
                     /translation="MNTITLVGRLVADAELKYLPNSGTPKITFSMAVDRRFKDKNGNK
                     ITDFIQCEQLGKHVENLVQYLVKGKPIYAVGELNIYNYKDENGCWKSITKVNVNALEL
                     LSSKNDNNAKQEYVPPGLDPQGFQAIDDDDIPF"
     gene            1130..1633
                     /locus_tag="KRH23_003836"
     CDS             1130..1633
                     /locus_tag="KRH23_003836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5227099.1"
                     /translation="MKYECEKVFLECDKGSFEINDTRAEEVTFEGTEIDNLFERVKYE
                     GTFTIISGWDSLLRDILWLEMRKVLKIITGKMMMGVLGMIIIRSQDKTDLVKADWINV
                     DKECVYAMFGDMDNFKKIGEYEDEKRAIQVLDNIQRFIEGGTRTDSIDSYKVRSYRNR
                     IFQMPVK"
     gene            1647..>1866
                     /locus_tag="KRH23_003837"
     CDS             1647..>1866
                     /locus_tag="KRH23_003837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5227100.1"
                     /translation="MLKVEKYFSGSLGTNIIDDDPTCRNYLALYCCVHGVRKNGELIF
                     PTCEKMLIEFNVDKNRKKKKKGSKVKLIN"
BASE COUNT          778 a          162 c          392 g          534 t
ORIGIN      
        1 ataaaaaaat actttgaaaa atatataggt gtgattactc ctaataactt tatagagtta
       61 atgagttact tagatgatgg aatggaagct gatgtaataa taagagctgt tgatgaagct
      121 gtaggcagtg gagttaagaa ttataagtat gtaaagacaa tcttaaataa ttggatagaa
      181 gcaggtgtaa aaactgtttt agaacttaca gaatatcaga atgaatttga aagaaagaaa
      241 aagagtaagc aggaaaagaa gcagtctaat agtaaaactg tgaatactca taatgtgaat
      301 aaaaataagt ttgctaactt caatcagact ttcactcaat atgaagaaaa agagctagat
      361 gagattatta aaaagagtca gaaggaaaaa tttaaataaa attaaacttc taggaagtaa
      421 atatcaatat attgcttcct agaaaagggg aggtataaaa tggcgagaat atatgcacaa
      481 agaagtggtt ctttaaatga acaagataga ttggagttat taagattact tgggaaagct
      541 ggatatacag taaaggttgc tagagagaag caaaatagca agacaactta tacttacttt
      601 gttgagtata cagaagaaca ggaagaaaaa tagaaggggg ctagttaaat gaatacaata
      661 actttagttg gaagattagt tgcagatgca gaattgaagt accttccaaa ttcaggtact
      721 ccaaaaataa ccttttcaat ggcagtagat agaaggttta aagataaaaa tggaaataaa
      781 ataactgatt ttattcaatg cgagcaatta ggaaaacatg tagagaattt agtgcaatat
      841 cttgttaaag gtaagcctat atatgctgtt ggagagttaa atatatataa ttacaaagat
      901 gaaaatggtt gctggaaatc tattactaag gttaatgtaa atgctttaga actactttct
      961 agtaaaaatg ataataatgc taaacaagaa tatgtaccac caggattaga cccacaaggt
     1021 tttcaagcaa tagatgatga cgatatacct ttttaattaa gttaaataat ctagggagta
     1081 attatgcaat attacttcct aggagttaaa aaatattgga ggtttaagag tgaaatatga
     1141 gtgtgagaaa gtgttcttag aatgcgataa gggaagtttt gagataaatg atacaagagc
     1201 tgaagaagta acattcgagg gtacagaaat agacaatctg tttgagagag taaaatatga
     1261 agggactttt acaataatat ctggatggga ttctttattg agagatatat tgtggcttga
     1321 aatgcggaaa gtcttaaaaa ttataacagg aaaaatgatg atgggggtat taggaatgat
     1381 aataattaga agtcaagata aaactgattt agtaaaagct gattggataa atgttgataa
     1441 agaatgtgta tatgcaatgt ttggagatat ggataacttt aaaaagatag gtgagtatga
     1501 ggatgaaaaa agggctatac aagtgctgga taatatacaa agatttattg aaggtggaac
     1561 tagaacagat tctatagaca gttataaggt tagaagttat agaaatagaa tatttcaaat
     1621 gccagttaaa tagggaggtt actgaaatgt taaaggttga aaaatatttt agtggttctt
     1681 taggaacaaa tatcatagat gatgacccta catgtagaaa ttacttagca ctatattgtt
     1741 gtgttcacgg agtaagaaaa aatggagaac ttatatttcc aacatgtgaa aaaatgttaa
     1801 tagagtttaa tgttgataaa aatagaaaaa agaaaaagaa aggttcaaag gtaaagttga
     1861 ttaatg
//
LOCUS       DAEORM030000147         1782 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.153, whole genome shotgun sequence.
ACCESSION   DAEORM030000147 DAEORM030000000
VERSION     DAEORM030000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1782)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1782)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 1782)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1782
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.153"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            <1..200
                     /locus_tag="KRH23_003838"
     CDS             <1..200
                     /locus_tag="KRH23_003838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ORF6N domain-containing protein"
                     /protein_id="HHS5227101.1"
                     /translation="FGVDLHRRLINKRRKMAEEGVSESKREKVNNLDVIQDDKKLIEG
                     YVAIVKDMALKYGISSDLSKN"
     gene            270..599
                     /locus_tag="KRH23_003839"
     CDS             270..599
                     /locus_tag="KRH23_003839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHS5227102.1"
                     /translation="MSVALQFIDTEDLVKELMGREDTVDFIKMFLDREGIKRMELMTI
                     EEFCEYLKISDVTARNMAREAMITKDFIALKIGRKYMIDRISFEEFIMKNAMKDRDVM
                     KKRKGVI"
     gene            732..914
                     /locus_tag="KRH23_003840"
     CDS             732..914
                     /locus_tag="KRH23_003840"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5227103.1"
                     /translation="MEVTKRFLEYKIQALSERIEFKKTIGYKCIADEKELGAYEDILL
                     MLNSEIESIGGVENEE"
     gene            904..1149
                     /locus_tag="KRH23_003841"
     CDS             904..1149
                     /locus_tag="KRH23_003841"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5227104.1"
                     /translation="MKSRQELIKDIEKYRKAQYLIYLDIVQRAWADRSLTADEQDRIK
                     QEAYAEYKRIERDTEEAEELLMREEFETDRPLAVQIM"
     gene            1232..1741
                     /locus_tag="KRH23_003842"
     CDS             1232..1741
                     /locus_tag="KRH23_003842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siphovirus Gp157 family protein"
                     /protein_id="HHS5227105.1"
                     /translation="MSTLYELATDLLEIEEGLTETTRNEAEKLEEIKEIIKQEIQNKN
                     TRIVSVILNIDSDINSIDSEIKRLQELKRVKKNTLDRLKSNIKDCMELLDTKKVETFL
                     GNISIRKSAGSLVIEDEEKIPAIYKTVEQVVKVDKNTIKDFIKKGHEVEGCRIEYSTT
                     LTTPKVKKE"
BASE COUNT          820 a          152 c          354 g          456 t
ORIGIN      
        1 gatttggagt tgatttgcat agaagattaa ttaataaaag aagaaaaatg gcagaagaag
       61 gtgtatctga atctaaaaga gagaaagtta acaatctaga tgtaatacaa gatgataaga
      121 agctaataga ggggtatgtg gctattgtaa aagatatggc tttaaaatat ggaatatcaa
      181 gtgatttaag caaaaattag gttaaatcat gacagtacct tgaaaactaa atacagaata
      241 tttaattaat atgagaagga ggtttgaaaa tgagtgtagc attacagttt atagatacag
      301 aagatttagt aaaagaatta atgggacgag aggatacagt agatttcata aaaatgtttt
      361 tagatagaga aggaattaaa agaatggagt taatgactat agaagaattt tgtgagtact
      421 tgaaaatatc tgatgtaaca gctagaaaca tggcaagaga agccatgata acaaaagatt
      481 ttattgcttt aaaaatagga agaaagtaca tgattgatag aatatcattt gaagaattta
      541 ttatgaaaaa tgcaatgaaa gatagagatg taatgaaaaa aagaaagggg gtgatttagt
      601 tgactctaag atggtttcta agattttgta taagacacaa gaaagtacct acaccaaagt
      661 tttacataga gtgtgtaact tatatggaag aatgtaaaca aagaggactt ggactttaag
      721 gaggattgaa tatggaagta actaaaagat ttttagaata taaaatacag gctctaagcg
      781 agaggataga atttaaaaaa acaattggat ataagtgtat agcagatgaa aaagaactag
      841 gagcatatga ggatattttg cttatgttaa attcagaaat tgaatcaata ggaggagtgg
      901 aaaatgaaga gtagacaaga attaatcaaa gatatagaaa aatacagaaa agcacaatac
      961 ttaatatatt tagatatagt acaaagagca tgggcagata gaagccttac agcagatgaa
     1021 caagacagaa ttaaacaaga agcatatgca gagtacaaaa ggatagaaag agatacagaa
     1081 gaagcagaag aactgctaat gagagaagaa tttgaaacag atagaccctt agcagttcaa
     1141 ataatgtaga aaagagccac tgcaatggct ctaatcaaaa acaaaaaata aatttaataa
     1201 ttatatatta tagcataaat ggagggaaat tatgagtact ttatatgaat tagctacaga
     1261 tttattagaa atagaagaag gtttaacaga aacaacaaga aatgaagctg aaaaactaga
     1321 ggaaataaaa gaaataataa aacaagagat acaaaataaa aacactagga tagtttcagt
     1381 aatattaaac attgacagtg atataaactc tatagattca gagattaaaa gattgcaaga
     1441 gttaaaaagg gtcaaaaaga atactcttga tagattaaaa agcaatataa aagactgtat
     1501 ggaattactt gatactaaaa aagtagaaac atttttagga aatataagta taagaaagtc
     1561 agcaggtagc ttagtcatag aagatgaaga aaagatacct gctatatata aaacagtaga
     1621 gcaagttgta aaagtagata agaataccat taaagacttt attaaaaaag gtcatgaggt
     1681 tgaaggttgt aggattgaat attcaactac attaacaact ccaaaagtta aaaaagagta
     1741 ggtgaaaact atggaaaata ataatattta tataaaactt gt
//
LOCUS       DAEORM030000148         1651 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.154, whole genome shotgun sequence.
ACCESSION   DAEORM030000148 DAEORM030000000
VERSION     DAEORM030000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1651)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1651)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 1651)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1651
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.154"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            complement(451..1032)
                     /locus_tag="KRH23_003843"
     CDS             complement(451..1032)
                     /locus_tag="KRH23_003843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HHS5227106.1"
                     /translation="MSNKKHWYDYLWIFSSIYLILGFVNIIFAWIGLICFFVPLAISI
                     VKGNKAYCNKYCGRGQLFNLLGNKLKLSRNRDIPKFIRSKWFRYGFLTFFMVMFANML
                     FSTYLVFEGSRNFKEVVTLLWTIKMPWQWAYHGTLVSPWVVQFAFGFYSVMLTSTVLG
                     LITMILFKPRSWCVYCPMGTMTQMICKAKSKSV"
     gene            complement(1025..1255)
                     /locus_tag="KRH23_003844"
     CDS             complement(1025..1255)
                     /locus_tag="KRH23_003844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HHS5227107.1"
                     /translation="MSNKKKKYANILANECVACGSCIKACPRSAISVPCGISAKINRD
                     LCVGCGICEKICPASVIEIITILKEEEGKCHE"
BASE COUNT          607 a          317 c          135 g          592 t
ORIGIN      
        1 tttacattta ttttttatgt atattttttg tttctaataa gttaatttga ctattttccc
       61 catactattt atatagaata ccttttataa gttataactt ctaatctttt tatatctata
      121 cttatattaa ttgtcatgac cttatttagt ttaaatactt gacctatttc atattaaata
      181 aatcttgcta ttaactggct tatatgtaat gaatatccat tcatataatg ttaattatta
      241 ttctattttc ttcaaataac tgaataattc ttaatatcta aattcattgt ttccacttag
      301 ccaataatct aagacataaa aaaaaagcat aaatcagttt accttacaca aactaaatct
      361 atgcccctat actcatatat ttgtcatata tattcaaacc tactactcat ctctacttga
      421 acaaaactgt aaatatcaca taaggccttt ctatacagac ttactctttg ccttacatat
      481 catctgagtc atagtaccca tagggcaata aacacaccat gaacgaggtt taaacaatat
      541 catagtaatc aaaccaagaa cagttgatgt aagcataaca ctataaaaac caaatgcaaa
      601 ctgtaccacc caaggtgaaa ctaaagttcc atgatacgcc cattgccaag gcatttttat
      661 agtccacaac aaagtcacta cttctttaaa atttctactt ccttcaaaca ctaaataagt
      721 tgaaaaaagc atattggcaa acattaccat aaaaaatgtc aaaaacccat atctaaacca
      781 cttacttcta ataaatttag gaatatctct atttcttgac agcttcaatt tatttccaag
      841 caaattaaac agttgtcctc ttccacaata cttattacag taagctttat ttcccttaac
      901 aatagaaata gctagtggaa caaagaaaca aattagccca atccaagcga aaataatatt
      961 tacaaatccc aatatcaaat atattgaaga aaaaatccat aaatagtcat accaatgttt
     1021 tttattactc atgacactta ccttcttcct cttttaatat tgttataatc tcaattacag
     1081 atgctggaca tatcttttca caaatcccac atccaacaca taaatctcta ttaatttttg
     1141 cactaatgcc acatggaact gagatagcac ttcttggaca tgcttttata cagctaccac
     1201 aagcaacgca ctcatttgct aaaatatttg catacttctt ttttttatta gacataataa
     1261 cctccctata ttattaatct ataagaatta tatcaagata cttacttttt atctgtgact
     1321 taatcacata aaacctcaat attaaaaatc acactctaaa tacaaaggag tttcaaataa
     1381 aaaacgatat gaagtcatta agtttagctt catatcgcct tttcttttgt gtatctatat
     1441 aaatatttat tatctaatat ttaatatatc tataatattt tcttatacag ctctataatt
     1501 ttacacctaa tcatattcta ttagtaacag gttaataccc atctaaaact ataactttat
     1561 tcacaatctt attctattag ccacaagtta aactcatatt gaagtttatc tttagttaca
     1621 ctcttactct attaaccaca agttaagccc a
//
LOCUS       DAEORM030000149         1633 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.155, whole genome shotgun sequence.
ACCESSION   DAEORM030000149 DAEORM030000000
VERSION     DAEORM030000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1633)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1633)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 1633)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1633
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.155"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            429..>1633
                     /locus_tag="KRH23_003845"
     CDS             429..>1633
                     /locus_tag="KRH23_003845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNRLRE domain-containing protein"
                     /protein_id="HHS5227108.1"
                     /translation="MRNIILYLNDDTFISKKYPDKNFSNLDYCLIGSKCSNSFVKEKL
                     ITFFKVRIPDILKDKSILKAELFIHINSNKNHIFKEKVDIEIKRISEYYNLRTITWND
                     RVSMENIRGYLPIGISDTSNYICLNITGTIKAWAMNKYPNYGLALSLNYPYQILEFTS
                     SRGCNKPYILVTFEDRIIDNCYPKCECLPIRITGPMGPRGATGSTGPTGVTGPTGNTG
                     VTGEIGPTGATGPTGSTGATGEIGPTGATGPTGSTGATGSIGPTGVTGPTGNTGVTGS
                     IGPTGVTGPTGATGVTGEIGPTGVTGPTGEIGPTGATGSTGVTGSIGPTGATGPTGPT
                     GVTGEIGPTGVTGPTGVTGEIGATGATGPTGNTGVTGEIGATGATGPTGNTGATGSIG
                     PTGVTGPTGA"
BASE COUNT          659 a          220 c          343 g          411 t
ORIGIN      
        1 gtggaaaaca cttatttcag tattttttaa acttatttta tttattctat ttaacaaaaa
       61 taaggttttt tataattttt acttataaaa aaatattgtt atggtaatat attctattta
      121 caattttata actttggttt acaataatat agacaataaa tcctaaaaaa cataataaga
      181 aaaaagtgct taatatttta gaaagactgg tttagtttac accagctaag ccagtcaagg
      241 aataatttaa agtgtaatat ataataatga aaaagaacgt gctattagaa atttctaatg
      301 acatgttctt tttttgtaga aatcagcatt attatataaa aatttaatac tataaatttt
      361 aattgtattg taactaagca tgtattttaa acatagtatg atatagaccc aaaatggagg
      421 gattataaat gagaaatatt atactttatt taaatgatga tacttttata tctaaaaaat
      481 atccagataa aaactttagt aatttagatt attgcttaat aggaagtaaa tgttcaaata
      541 gttttgtaaa agaaaagttg attacttttt ttaaagtgag aataccagat atattaaaag
      601 acaaaagtat attaaaagca gagttattta ttcatattaa ttcaaataag aatcatattt
      661 ttaaagaaaa agtagatatt gaaattaaaa gaataagtga atattataat ttacgaacta
      721 taacatggaa tgatagagtg tctatggaaa atatcagggg atatttacca attgggataa
      781 gtgatacatc caactatatt tgtttaaata ttacgggaac tataaaagca tgggcaatga
      841 ataaatatcc taattatggg ttagctttat ctttaaatta cccttatcag attcttgaat
      901 ttacatctag tagaggttgt aacaaaccgt atatacttgt aacatttgaa gatagaatta
      961 tagataattg ttatcctaaa tgtgagtgtc ttccaattag aattacaggt ccaatgggac
     1021 caagaggagc gacaggaagt acaggaccaa cgggagtaac aggtccaacc ggaaatacgg
     1081 gagtgacagg agaaataggg ccaacaggag caaccggacc aaccggaagt acaggagcga
     1141 caggagaaat agggccaaca ggagcaaccg gaccaaccgg aagtacagga gcgacaggaa
     1201 gtataggacc aacaggagta acaggtccga caggaaatac gggagtgaca ggaagtatag
     1261 gaccaacggg agtaacaggc ccaacaggag cgacaggagt gacaggagaa ataggcccaa
     1321 caggagtaac aggcccaaca ggagaaatag gaccaacggg agcaacaggt tcaacaggag
     1381 tgacagggag tataggacca acgggagcaa caggaccgac aggcccaaca ggagtgacag
     1441 gagaaatagg accaacggga gtaacaggcc caacaggagt gacaggagaa ataggagcaa
     1501 cgggagcaac aggaccaaca ggaaatacag gagtaacagg agaaatagga gcaacgggag
     1561 caacaggacc aacaggaaat acaggagcga caggaagtat agggccaacg ggagtaacag
     1621 gtccaacagg agc
//
LOCUS       DAEORM030000150         1552 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.156, whole genome shotgun sequence.
ACCESSION   DAEORM030000150 DAEORM030000000
VERSION     DAEORM030000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1552)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1552)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 1552)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1552
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.156"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            129..>1552
                     /locus_tag="KRH23_003846"
     CDS             129..>1552
                     /locus_tag="KRH23_003846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp28"
                     /protein_id="HHS5227109.1"
                     /translation="MKFYKRILTLTLSISFVFANIQLVDAISSVEKIQGKNKYEIAGK
                     IADKNAYKTAILINTSNSIADGLSASGLAGALNAPILLTEKNTIPTETSARLKNVSKV
                     YIIGGTYSISTSVENSLKSKKIKVVRIKGNDRIKTSYNVAKEINSIKKVNTVMLTNAY
                     KGEADAISIASVAARDKAPIILTNGQSIPFSTSGLKSYVIGGTASMNTTLVNNTKSTR
                     LGGSTRFETNKAIINKFYKDAREFYIAGAYELTNALVGSSLSKHGPMVLVNDGSNKSI
                     LKNAKKITSIGYIDSNIVQQCLNITNGIGDINTGVVKNVKPTTKTIKDGMYKVGKDIS
                     AGEYLITSNSGSYASYYEVTSDSTGNADSILSNDIFSGTRYITLKNGQYIKIEDSTMT
                     LAKYAKAQKAKNGKFGNGMYKIGLEIPAGEYIIMSNSSDAYYEVRNDSLGNAEGIVTN
                     DTFSGRRYITVEEGQYLILNDCYL"
BASE COUNT          636 a          162 c          262 g          492 t
ORIGIN      
        1 tgtattaata tttatttgta atatacttaa tataatttgc aattttacat aagtttgtta
       61 agtacataac taatttaaga atatgtattt atatattaaa aatttattat gagggggaca
      121 attttattat gaaattctat aaaagaatat taacattgac tttaagtatt tcttttgtat
      181 ttgcaaatat tcaattagta gatgcaatat catctgtaga aaaaatacaa ggaaaaaata
      241 agtatgaaat agcaggtaaa atagcagata aaaatgcata taaaactgct atattaatta
      301 atactagtaa ctctattgca gatggattaa gtgcaagtgg actagcagga gctttaaatg
      361 cccctatact attaactgaa aaaaatacta taccaactga gacatctgca agattaaaaa
      421 atgtatcaaa agtttatata attggaggaa catattctat tagtacatct gtcgaaaatt
      481 cattaaaatc taagaaaata aaagttgtaa gaattaaggg aaatgacaga ataaaaacaa
      541 gttataatgt tgcaaaagaa ataaattcaa taaaaaaagt caatactgtt atgctaacca
      601 atgcatataa aggagaagca gatgctataa gtattgcatc tgtagcagca agagataaag
      661 caccaataat tcttactaat ggacaaagta tacctttttc aactagtggt ttaaagtctt
      721 atgtaatagg aggaacagct tcaatgaata ccactttagt aaacaatact aaatctacta
      781 gactaggggg gagtactcgt tttgaaacta ataaagcaat aataaataag ttttataagg
      841 atgctagaga gttttatata gctggagctt atgaattaac aaatgcactt gtaggatctt
      901 ctttatcaaa acatggtcca atggttttag ttaatgatgg tagcaataaa agcattttaa
      961 aaaatgctaa gaagataact tctataggat atatagattc aaatatagta caacagtgtt
     1021 taaatataac aaatggaatt ggagatatta atactggggt tgtaaaaaat gttaaaccta
     1081 ctacaaagac tataaaagat ggaatgtata aggttggaaa agatatatca gcaggtgaat
     1141 acttaataac ttcaaactca ggaagttatg cttcttatta tgaagttaca agtgatagta
     1201 caggtaatgc tgatagtata ctttcaaatg atatttttag tgggactaga tatatcacct
     1261 taaagaatgg tcaatatatt aaaattgagg attcaacaat gacattagca aagtatgcta
     1321 aagcccagaa ggccaagaat ggtaagtttg gaaatggtat gtataaaatt ggattagaaa
     1381 ttcctgctgg agaatatatt ataatgtcaa attcttctga tgcatattat gaagttagaa
     1441 atgatagctt aggtaatgca gagggaatag ttactaatga tactttttca ggaagaagat
     1501 atataacggt tgaggaaggt caatatttaa tattaaatga ttgttattta at
//
LOCUS       DAEORM030000151         1539 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.157, whole genome shotgun sequence.
ACCESSION   DAEORM030000151 DAEORM030000000
VERSION     DAEORM030000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1539)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1539)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 1539)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1539
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.157"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            complement(402..893)
                     /locus_tag="KRH23_003847"
     CDS             complement(402..893)
                     /locus_tag="KRH23_003847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfbM family protein"
                     /protein_id="HHS5227110.1"
                     /translation="MGMIGCYTKISEENVFKLQQAEENLQDFVFEDANENSTINIDKA
                     WHAIHFTLTGCPFGGDDDNIFSKLVLSGNILMEIDGEFPVMLITANDVKKLSKAMNSL
                     EEQAFRKRFNINEMLENNIYPVINDESEDDFFEYVWANLIELKKFIQEASNDGLAVIF
                     FIM"
BASE COUNT          585 a          189 c          136 g          629 t
ORIGIN      
        1 atttttctgt ttttaattaa attaaagtat ctttgtttct gaaatttttt aagtttatga
       61 agttataatt taatatatat ttattttatt tgtgagtcta tttttatata taatgaaaaa
      121 tgtgataagt atccaaaaga attactggat ataataagat agggtattta gccttttaag
      181 ataaataaaa atatctgcaa ctatatattg caaaaattta aaactaattt atatatgcta
      241 atataaatat ttataaagac ataagacaaa tttacctaca gatttaaatt taacttatat
      301 attttaaaag gctaatataa tatgtatttt cttctataca atcaaaaggc ttcatatcta
      361 agatatgtga tgacactaat attcacaatt tttagtaatt atcacattat aaaaaatatt
      421 acagctagtc catcattaga tgcttcttgt ataaactttt taagctcaat tagatttgcc
      481 catacatatt caaaaaaatc atcttcactc tcatcattta taacaggata aatattattt
      541 tctaacatct cattaatatt aaatcttttt ctaaatgctt gttcttccaa actgttcatt
      601 gcttttgata gtttttttac atcatttgct gtaatcaaca tgacaggaaa ttctccatca
      661 atttccataa gtatgtttcc acttagtact aatttgctaa atatattatc atcatctcca
      721 ccaaaaggac aacctgtcaa agtaaagtga atggcatgcc atgctttatc aatattgata
      781 gtactatttt cgttggcatc ttcaaaaaca aaatcttgta aattttcttc tgcttgctgt
      841 aatttaaaaa cattctcttc acttatttta gtataacatc ctatcatccc cataattaca
      901 ttcctcctaa gtagcgtttt tttaattgta acttataatt aaacttagtt acaataaaat
      961 atattgagaa aagtattatt tcatcttaaa tttaaatacc tatattatca actaaaattc
     1021 tgtgtttata gcgtaagtat tattattttt tcctaaaaat taaatgaatc agaagttcta
     1081 taggtaatat tgactataaa taagaactat tacttttaaa aaaaaattta agaaattata
     1141 ctgtagaatc atgctctact tattagcttt aaataaaaaa taaatcatgt tctcaaatta
     1201 aataataaat aacaataaat ttaaatttta aactataaga gtttctggag tgttaataag
     1261 cataccaata attatatgtg taagaatttg atttaataga tatgaataat ttttacatta
     1321 attataaata tattaaccta ttgttataaa ttctaaaaaa gaaaagttat cttaaataaa
     1381 aaataagtgt atcttaaatt ttaaatgata cacttatttt tatattgaaa ttatattttt
     1441 taatatctat tcttaattag gtatttttaa attatctgtt tacattaaat atctcttaat
     1501 tacttatctt tcagctagct tcttctatta aatgtttct
//
LOCUS       DAEORM030000152         1374 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.158, whole genome shotgun sequence.
ACCESSION   DAEORM030000152 DAEORM030000000
VERSION     DAEORM030000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1374)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1374)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 1374)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1374
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.158"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            <1..630
                     /locus_tag="KRH23_003848"
     CDS             <1..630
                     /locus_tag="KRH23_003848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polymorphic toxin type 50 domain-containing
                     protein"
                     /protein_id="HHS5227111.1"
                     /translation="VEKYEIIATLDLRTSNICRELDGKVFDMKDYQVGVTAPPFHCRC
                     RTTTAPWFEDEEGYRAAKGEDGKTYYVPSSMKYNEWYEKYVKHNSILEIKNSAIIDSI
                     KEDIKNGKYNLNIHDGKQGKHLKEHNNYIEGRSYLTITKEEAQELVNKHAGNGIIKFN
                     RSGEWDKKELIEVDKNIGVNVNNITGEKTLTNKFKIHYSKTGTHIVPAL"
     gene            645..845
                     /locus_tag="KRH23_003849"
     CDS             645..845
                     /locus_tag="KRH23_003849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5227112.1"
                     /translation="MKLWEYVGKNVQITCVDKQIIRGKCDGYTQALDNEPEIASISIA
                     RDGYGIEVYENEIESIENINKE"
     gene            911..>1374
                     /locus_tag="KRH23_003850"
     CDS             911..>1374
                     /locus_tag="KRH23_003850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0019069 - viral capsid assembly [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage scaffolding protein"
                     /protein_id="HHS5227113.1"
                     /translation="MDWLKELLEGIKIEDNKIDVASLQKSIEKKIKETTITQEDYTNL
                     ETQLNTANETIKKFEGGMTKEDVENLKTTYETDKKTLEETYKKEIEEKDFNYWLNDAF
                     KSIKCRDEIALKAHLDIEALRNSKDRQKAFEEQINPLKQDKDYLFNATLEGE"
BASE COUNT          621 a          124 c          267 g          362 t
ORIGIN      
        1 gtagagaaat atgagattat tgctacatta gatttaagaa cttcaaatat atgcagagag
       61 ttagatggaa aagtatttga tatgaaggat tatcaagttg gagttacagc tccaccattt
      121 cattgtcgtt gtaggacaac aacagctcct tggtttgagg atgaagaagg ttacagagca
      181 gcaaaaggag aagatggaaa aacatattat gtaccatcta gtatgaagta taatgagtgg
      241 tatgagaagt atgttaaaca taatagtatc ttagaaataa aaaatagtgc tataatagat
      301 agcataaaag aagatattaa aaatggtaaa tataatttaa atattcatga tgggaaacaa
      361 ggaaaacatt taaaagagca taataattat atagaaggaa gaagctattt aactataaca
      421 aaagaagaag ctcaagaact tgtgaataag catgctggca atggaatcat aaaatttaat
      481 cgaagtggag aatgggataa aaaagaactt atagaagttg ataagaatat aggggtcaat
      541 gttaataata ttacgggtga aaaaactctt acaaataagt ttaagataca ttattccaaa
      601 actggaacac atatagtacc agctttataa ggaggaaaaa taaaatgaaa ttatgggaat
      661 atgtagggaa aaatgttcaa ataacttgtg tagataagca aataataaga ggaaagtgtg
      721 atggatatac acaagcttta gataatgaac cagaaatagc aagtatatca atagctaggg
      781 atggttatgg aattgaagtt tatgaaaatg aaatagaatc tatcgaaaat ataaataagg
      841 aatgactaag catgtactta aaaataagta gatgctttta ttttgtaaaa aatgaaagga
      901 gaaatttaaa atggattggt taaaagaatt gctagaagga ataaaaatag aggataacaa
      961 gattgatgta gcttctttac aaaagtctat agaaaagaaa ataaaagaga ctacaattac
     1021 tcaagaagat tatacaaatc ttgaaacaca gcttaataca gctaatgaaa ctattaaaaa
     1081 gtttgaagga ggtatgacaa aagaagatgt agagaatcta aaaacaactt atgaaactga
     1141 taagaaaact ttggaagaaa cctacaaaaa agaaattgaa gaaaaggact ttaattactg
     1201 gttaaatgat gcttttaagt ctattaaatg tagggatgaa atagcgttaa aagctcattt
     1261 agatatagaa gcactaagaa atagtaaaga tagacaaaaa gcttttgaag agcaaataaa
     1321 ccctttgaaa caggataaag attatttgtt taatgcaaca ctagaaggtg aaga
//
LOCUS       DAEORM030000153         1293 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.159, whole genome shotgun sequence.
ACCESSION   DAEORM030000153 DAEORM030000000
VERSION     DAEORM030000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1293)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1293)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 1293)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1293
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.159"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            122..1066
                     /locus_tag="KRH23_003851"
     CDS             122..1066
                     /locus_tag="KRH23_003851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HHS5227114.1"
                     /translation="MQKNKKEGALLKKYFGEIGLIFIAIIWGSGFVATQFALDGGLTP
                     LQIITLRFFLAAIIMNLLFFKQIRANMGKKLLKAGGILGIFLFLAFTVQTIGLMYTTP
                     SKNAFITAANVVIVPFIGFILYRRKLDKIGIISSLVALIGIGILSLEADFSINFGDFL
                     TLICSFGFAFHIFFTSEFAKDNNPMALTAIQFTVAFLMSVVVQTFAGQLKMEAELSGY
                     MGTMYLAVFSTTIGFLFQTICQKRVDGTRTAIILSTEAVFGTIFSIIILKELITAKLV
                     IGSILIFVAIITAETKLSFLKSKKVKLKDSEESSLESI"
BASE COUNT          469 a          143 c          214 g          467 t
ORIGIN      
        1 gatataaatt tgagctcaaa atgtatgtaa atttagattt aaaatactga aaaaatttac
       61 tatattaatt tatagtaatg cttatagaaa aactctcttg ctgtttaggg ggtttataat
      121 tttgcaaaaa aataaaaagg agggggcttt attgaaaaaa tactttggag aaataggact
      181 aatatttata gcaattatat ggggaagtgg ctttgtagca acccaatttg cattagacgg
      241 tgggcttaca cctctacaaa tcataacttt aagatttttc ttggcagcta taattatgaa
      301 tttactgttt tttaaacaga ttcgtgccaa tatgggtaaa aaattattaa aagcaggagg
      361 gattttagga atatttttat ttctagcatt cacagtacaa actattggac ttatgtacac
      421 tacaccatct aaaaatgcgt ttataacagc agctaatgtt gtaatagttc cgttcatagg
      481 atttatactt tatagaagaa aacttgataa aataggaata ataagtagtt tggtagctct
      541 tataggaatt gggatacttt ctttagaagc tgatttctct attaattttg gagattttct
      601 aacacttata tgttcattcg gatttgcatt tcatatattc tttacaagtg agtttgcaaa
      661 agataacaac ccaatggcat tgacagctat tcaatttaca gtagcgtttt taatgtctgt
      721 tgtagttcaa acatttgcag gtcaattaaa gatggaagct gaattatctg gttacatggg
      781 aactatgtat ctagctgtat ttagtactac aattggattt ttatttcaga ctatatgtca
      841 aaaaagagtt gatggaacta gaacagctat aatattatcc acagaggctg tatttggtac
      901 aatattttct ataataattc taaaggaact tattacagca aaattggtta ttggtagtat
      961 cttgatattt gttgcaatca taactgcaga aactaaatta tcttttttaa agagcaaaaa
     1021 agtgaaactt aaagattcag aggagtcttc attagaaagt atttaatatg acaactattt
     1081 cctaattaat caaataaatt atgtattatg tagaaatttg acatcaaaac ttggttgata
     1141 ctggtgtttc aaagtgataa aattaattag gaaataaatt ttatttttag tgtttaagct
     1201 ataaagtctg gggtatatat attcttgtag caagttatta aacttaaaaa taaaaattta
     1261 attatataaa attgggagga aattaattat gaa
//
LOCUS       DAEORM030000154         1229 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.160, whole genome shotgun sequence.
ACCESSION   DAEORM030000154 DAEORM030000000
VERSION     DAEORM030000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1229)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1229)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 1229)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1229
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.160"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            complement(532..921)
                     /locus_tag="KRH23_003852"
     CDS             complement(532..921)
                     /locus_tag="KRH23_003852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HHS5227115.1"
                     /translation="MTIKKLPQSELKIMKFIWKSDSKVTSRDIVLGMEQKYQWKQTTT
                     LTLLSRLVVKRFLNSQKIDKYTHYEVLIKEKEYIGVETRDFFRNIHDSSIKSLLLSLH
                     ENINLSKDDILLIEEWIKNLKEEEKDV"
BASE COUNT          400 a          187 c           90 g          552 t
ORIGIN      
        1 tattcagtac tttctatcaa tcttttgttt ttattttttc aatatcttct attaatactt
       61 ttatttctac ctcttcagta tcttatatca atcttttatt ttttcaatat cttctattaa
      121 tacttttgtt tctatctctt taatatctta tattaatcct ttatttttat tttttcaata
      181 tcttcattaa ttcctattta ttttatcatc ttaaatacga aaacactgtg tcatatttgc
      241 aaaatatata ttatcatcta tattaaagct tcacaattta tatttaaaaa ttctctttaa
      301 ttacactacc tctatttaaa aagctacctt aattatactt ataagtaaag gtagcttttt
      361 aaatttaatt aaatagaata tccactatta atttatattt aatttattta gattcacatt
      421 atagtatcat aatccactta taatcatttg tcatattact taagtagact aatatattac
      481 ataaatacac ttacatacac tttatattga tgctataaga aatacgtttg cttatacgtc
      541 tttctcctct tcttttagat tttttatcca ctcttcaata agtaagatat catctttgct
      601 caaattaata ttttcatgta atgacaacaa taaacttttt atagaagaat catgaatatt
      661 tctaaaaaaa tctcttgtct caactcctat gtattccttt tctttaatta aaacttcata
      721 atgtgtatat ttatctatct tttgagaatt tagaaatctt tttactacta atctagataa
      781 aagagtcaaa gttgtcgttt gtttccattg atatttttgc tccattccta aaacaatatc
      841 tctagatgtt actttggaat ctgatttcca tataaatttc attatcttta attctgattg
      901 tggcaacttt tttatagtca tgataaaacc ttgctactca gaatatagac aagcaatatc
      961 cataataaaa tttttcgatt aaatacatct tatacggatt tatataagct cagacttata
     1021 agatattttt caatcttaat cctaaattta gctatttgta cacggtaaat atatataaat
     1081 aatgtcaaaa ttctcttgta ttatattgct taattttatg aaatattttg tactcagcta
     1141 tctattttgg atacttgtcc agtagctctc ctttctttta aactctttga ttttaaatat
     1201 ttgtatttca gtaaatccta cttcctaaa
//
LOCUS       DAEORM030000155         1169 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.161, whole genome shotgun sequence.
ACCESSION   DAEORM030000155 DAEORM030000000
VERSION     DAEORM030000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1169)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1169)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 1169)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1169
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.161"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            complement(345..851)
                     /locus_tag="KRH23_003853"
     CDS             complement(345..851)
                     /locus_tag="KRH23_003853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase"
                     /protein_id="HHS5227116.1"
                     /translation="MGFREVKIEELQFNPFTKIGKEWLLITAGDSEKFNTMTASWGGV
                     GVYWGKNVVTTYIRPQRYTKEFVDSNDTFTVAFFDETYREALNICGTISGRDINKIEK
                     AGLTPYFVDDTVAFEEANMIIVCKKLYHGNMPPENFDAKENDKKWYPEKDYHTMYISE
                     IIKVLVKE"
BASE COUNT          422 a          168 c          105 g          474 t
ORIGIN      
        1 tatactttta tagtactata ttgaataaaa ttaactttga aattatttac attaaaataa
       61 atcaagtaca aatgccataa attaagtgtt tctagttagc ataaaaatac ttataaagta
      121 tactcaaata tttcaaataa atacttttat tcaaataaat ctctacttat ataagtgctt
      181 atataaataa aaagatgaac tatagtaaat atagttcatc ttttttataa tagtatttat
      241 ttaaaattaa tatttattta gttactagca tctacttaga tatcagataa gaaagcacag
      301 tcatttactt ataataagtt cttttcatat attttttatt ataattattc ttttacaaga
      361 acttttataa tttctgaaat gtacatagta tggtagtctt tctctggata ccatttttta
      421 tcattttctt tagcatcaaa gttttctggt ggcatattac catgatatag ctttttacat
      481 actataatca tattagcttc ttcaaaagct accgtatcat ccacaaaata tggtgtaagt
      541 cctgcttttt ctattttatt tatatctcta ccagaaatag taccacaaat atttaaagcc
      601 tctctatacg tttcatcaaa gaaggcaact gtaaatgtat cattactatc tacaaattct
      661 tttgtatatc tctgtggtct tatgtaagtt gtaacaacat ttttacccca atagactcca
      721 acaccacccc agctagcagt cattgtgtta aacttttctg aatcaccagc tgttataagt
      781 aaccattctt tgccaatctt agtaaatgga ttaaactgta attcctcaat ttttacttct
      841 ctaaaaccca tgacttcatc ctacccttca ttttttaatt atataaatta attgttaaaa
      901 atttgaatat atgtactctt ataatactga cttttgattg tcctacataa ttcatgtaaa
      961 ttataataca acaaatcaat tactttcgca ataagtagtt ttcatatttt ataagtgtaa
     1021 aatatagata aaatatattg attataaagt atataatata tttttaaacc taaagcaata
     1081 tacaataaaa aaatgtagaa agtaagtatc tctctacatt ttttattgta tattattttt
     1141 atattaattt aattttatct tgattcagt
//
LOCUS       DAEORM030000156         1147 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.162, whole genome shotgun sequence.
ACCESSION   DAEORM030000156 DAEORM030000000
VERSION     DAEORM030000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1147)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1147)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 1147)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1147
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.162"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            complement(210..920)
                     /locus_tag="KRH23_003854"
     CDS             complement(210..920)
                     /locus_tag="KRH23_003854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytR/AlgR family response regulator
                     transcription factor"
                     /protein_id="HHS5227117.1"
                     /translation="MTSICICDDEKQQRNMLNKIITREMDLWGYPYKIKEYSNGESLV
                     YNLEHENYYIDIIFLDIELGKSNGVDIAKTIRKHSKDTIIIFVTGFSDYVFHGYDVGA
                     LNYILKPYKTEKICKVLKEALKKLEQWKENFITVQIGTNLCKINTKDILYFKSELRKL
                     TVVTFDKTLEYYGKLNDMETVLPSNFIRTHQRYIVNLNHVDSITQTYAKVQNEKIPIS
                     RKKYQEVVGKFTRYMLES"
BASE COUNT          412 a          151 c          124 g          460 t
ORIGIN      
        1 ttgaaagatt gaaattctag aaactgagct ttaaaaaatt aagtttgaaa aaaactctaa
       61 aaactaagct tcaaaaaatt aaattttgaa agattgaaat tctagaaatt aagcttcaaa
      121 aaattaaatt tgaaaaaaca aaactctaaa aactaagctt taaaaagtta agtttcaaaa
      181 ataaaattct agagattgaa cttcaaaaat taagattcta acatatacct tgtaaatttt
      241 cctacaacct cttgatattt tttacggctt ataggaattt tttcattctg aactttggca
      301 taagtttgag ttatactatc tacatggttt agattgacaa tatacctttg atgcgtacgt
      361 ataaaattag agggaagaac agtttccata tcatttaatt ttccgtagta ttctaatgtt
      421 ttatcaaagg taactacagt taattttctt agctcacttt taaagtagag gatatctttt
      481 gtattaattt tacaaagatt agttccaatc tgaactgtaa taaagttttc tttccattgt
      541 tctaattttt ttagtgcttc ttttaatact ttacatattt tttcagtttt ataaggtttt
      601 aagatgtagt tcaaagctcc tacatcatat ccatgaaata catagtcaga aaaacctgtg
      661 acaaagatga ttatagtatc ttttgaatgt tttcgtatag tttttgctat gtcaacgcca
      721 ttactttttc caagttcaat atctaaaaaa ataatatcta tgtaataatt ttcgtgttct
      781 agattgtata ctagactttc tccatttgaa tattctttta ttttataggg gtagccccac
      841 aaatccattt ctcttgtaat gattttattc agcatgtttc tttgttgttt ttcatcatca
      901 caaatacaaa tcgaagtcaa ttttttatct cctttcaaat tttatattta tatagttaag
      961 tatataatat attttgctac ctagatatat aaaatgaaat aacaattata tccagatagc
     1021 aaaataaaat tttttatatt agtatactta cacttaaaac tattctatta aacttattct
     1081 gaagtgctaa tgattttctt attaaaaaat ctaataatct ttcttattat aaaatacaaa
     1141 tgctttt
//
LOCUS       DAEORM030000157         1124 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.163, whole genome shotgun sequence.
ACCESSION   DAEORM030000157 DAEORM030000000
VERSION     DAEORM030000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1124)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1124)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 1124)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1124
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.163"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            210..914
                     /gene="cwlD"
                     /locus_tag="KRH23_003855"
     CDS             210..914
                     /gene="cwlD"
                     /locus_tag="KRH23_003855"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008745 - N-acetylmuramoyl-L-alanine
                     amidase activity [Evidence IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase CwlD"
                     /protein_id="HHS5227118.1"
                     /translation="MRKYIKHIIFSFAMICLVVVSIFEIKNISEDVIKYMPVTNKTII
                     LDAGHGGIDPGALNKDKSTSEKDINLAITLKLRELIESSGGLVILTREDDSSLYKEEN
                     NKTTRQKYNENLKNRKEIISNSNANMFVSIHLNAFEQSKYYGAQTFYPKDKQDSKELS
                     KCIQEELKRVVDKTNNREVKPRDDIYLLKENNIPSVLIECGFLSNEKECKLLTDETYQ
                     EKIAWAIYIGIQKYLS"
BASE COUNT          503 a          111 c          170 g          340 t
ORIGIN      
        1 ataatataaa ctaagtataa tttattgtat agtattgaat gttagataaa catagtgaat
       61 taaataggga cagaaatata atatcattac ataataatat attaatacca ataaataaag
      121 atatatcaat attaaaaaaa tttaaatgtt tgtactaata tatggaatat tatagtgttt
      181 ttataagtat acatatacag ggtgatgttg tgagaaagta cataaaacat ataattttta
      241 gttttgcaat gatatgtcta gtagtagtat ctatatttga aattaaaaat atttctgaag
      301 atgttatcaa gtatatgcca gtaacaaaca aaactataat tttagatgct ggtcatggag
      361 gcattgatcc aggtgcatta aataaggata agagtacatc tgaaaaggat attaacctag
      421 caataacact taagcttaga gagcttatag aatcaagtgg tggccttgta atattaactc
      481 gagaagatga cagtagcctt tataaagaag aaaataataa aactacaaga caaaaatata
      541 atgagaattt gaaaaataga aaagaaataa tatctaattc taatgccaat atgtttgtct
      601 ctatacatct taatgcattt gaacaatcaa aatactatgg agctcaaact ttttatccta
      661 aagacaaaca agacagtaaa gaattatcga agtgtattca agaagaactt aaaagagtag
      721 tagataagac aaacaacaga gaagtcaaac caagggatga tatatatctt ttgaaagaaa
      781 ataatattcc atcagtactg atagaatgtg gttttttatc aaatgaaaaa gagtgtaaac
      841 tcttaactga tgaaacatat caagaaaaaa tagcatgggc aatctacata ggaatacaaa
      901 aatatttaag ttgaaataac tataaaaata ggtctaaata tgtaaatagc ttgtattaaa
      961 gcagttaaaa tgcattaata taggctattt ttattttgac aaaaaaatat ttaaaataaa
     1021 agttaaaaag ttgttgactt agaataatat agatgatatt atatatgagt gcccaaaagg
     1081 agcaccaaaa taagacaaaa gaactttgaa aattaaacag tagg
//
LOCUS       DAEORM030000158         1120 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.164, whole genome shotgun sequence.
ACCESSION   DAEORM030000158 DAEORM030000000
VERSION     DAEORM030000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1120)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1120)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 1120)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1120
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.164"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            <1..993
                     /locus_tag="KRH23_003856"
     CDS             <1..993
                     /locus_tag="KRH23_003856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="baseplate J/gp47 family protein"
                     /protein_id="HHS5227119.1"
                     /translation="NTLDKREGSIIYNALAPVAVELTETYIAMDELLDQTFVDTASYY
                     YLEKRCKERGITPLPATNTIAKGVFNIDIPIDSRFNLGEYNYVAIERISEKTYKMKCE
                     TTGPVFELGQLIPIEYVDKLETAELTEILINGEDEESEDSLRQRYYDSLNSQSFGGNI
                     QNYKDEVNKIQDVGGVKVYPVWDGGGTVKLVIINSNFKVPSEDLVNLVQEEIDPIGHQ
                     GQGLGLAPIGHKVTVTGVVSTTINISADITYKNGYTWENIKSIAEEAVDDYLNELNMS
                     WEDEENLIVRISQIETRLLSIDGVLDITNTMINDVKSNLTIDSNSIVVRGEVVG"
BASE COUNT          463 a          131 c          213 g          313 t
ORIGIN      
        1 aacacacttg ataagagaga aggttctata atatacaatg ccttggcacc agttgcagtg
       61 gagcttacag aaacatatat tgctatggat gaattactag accaaacatt cgtagatact
      121 gctagttatt attatttaga gaagagatgt aaagagagag gtattacacc tttacctgca
      181 accaatacaa ttgcaaaagg agtttttaat atagatattc ctattgattc aagattcaac
      241 ttaggagaat acaattatgt agcaattgag agaatatctg aaaaaacata taaaatgaaa
      301 tgtgaaacta ctggacctgt atttgaactt ggtcagttga ttccaattga atatgtagac
      361 aaattagaaa ctgctgagtt aactgaaata ctaattaatg gagaagatga agaaagtgaa
      421 gatagtttaa gacaaagata ttatgatagc ctaaattcac agagctttgg tgggaatata
      481 caaaactata aagatgaagt taacaaaata caagatgttg gaggagttaa ggtttatcct
      541 gtgtgggacg gtggaggaac tgttaagtta gtaataatta actctaattt caaagtacca
      601 tcagaggatt tagttaattt agtgcaagaa gaaattgacc caattggaca tcaaggacaa
      661 ggcttaggat tagcaccaat agggcataaa gttactgtta caggtgttgt aagtacaact
      721 ataaatatat cagcagatat aacatacaaa aatggctaca cttgggagaa tataaaatca
      781 attgcagaag aagcagttga tgactattta aatgaactta atatgagttg ggaagatgaa
      841 gaaaacttaa tagtccgtat atctcaaatt gaaactagat tacttagtat agatggagtg
      901 ttagatatta caaacacaat gataaatgat gttaaatcta atctaacaat agatagtaac
      961 agtatagtag tgagaggtga ggtagttgga taaagagatt aatctaataa attacttacc
     1021 acaaattcta caagataaag aagaatatat aaaagtattt aatgtagaaa acaaagaaat
     1081 aaaaacacta catgaaaaat taaatgacct atcaagtgac
//
LOCUS       DAEORM030000159         1105 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.166, whole genome shotgun sequence.
ACCESSION   DAEORM030000159 DAEORM030000000
VERSION     DAEORM030000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1105)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1105)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 1105)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1105
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.166"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            <1..388
                     /locus_tag="KRH23_003857"
     CDS             <1..388
                     /locus_tag="KRH23_003857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="diaminopropionate ammonia-lyase"
                     /protein_id="HHS5227120.1"
                     /translation="AGDGKPRFVGGDMPTIMAGLACGEPNTIGFEVLKNHAAAFVSAP
                     DWVSAKGMRTLGNPLNGDEKVISGESGAVTTGLLVAAMEREDLADLRKDLKLDENSRI
                     LLISTEGDTDPDKYRSIVWDGEYPSI"
     gene            515..>1105
                     /locus_tag="KRH23_003858"
     CDS             515..>1105
                     /locus_tag="KRH23_003858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HHS5227121.1"
                     /translation="MLNEQRKQEVTEICQKLIQNPSSSGNEEGVVKAIEESFEKLGFD
                     SWSRDRYGNIVGCIKGNKPGKKILFDGHIDTVPVPDASKWSVPPFEGKIVDGKIYGRG
                     TSDMKGQYTAMMSAVAYFAKDTNRDFAGELYVAGVVHEEIFEGVSAREISKAVQPDYV
                     VIGESSELNLKIGQRGRGEIVVETFGKPAHSANPEKG"
BASE COUNT          427 a          117 c          246 g          315 t
ORIGIN      
        1 agctggagat ggaaaaccaa gatttgttgg aggagatatg ccaactataa tggcagggct
       61 tgcttgtgga gaaccaaata ctataggatt tgaagtatta aaaaatcatg cagcagcatt
      121 tgtttcagca ccagactggg tttctgctaa aggtatgaga acattaggta atcctttaaa
      181 tggtgatgaa aaggtaattt ctggagaatc tggagcagtt acaactggtc ttttagtagc
      241 agctatggaa agagaagatt tagcagattt aagaaaagat ttaaaattag atgaaaattc
      301 aagaatactt ttaataagca cagaaggaga tactgaccct gacaaatata gaagtatagt
      361 ttgggatgga gaatatccaa gtatataagg aattactaaa atgcaattat tagatattgg
      421 tttacatatt tagaagatat ataagttcta aaatttagaa aatatataag tatataaaat
      481 acatacatta taaaaaattt agggggataa tgaaatgtta aacgaacaaa gaaaacaaga
      541 agtaactgaa atatgccaaa aattaattca aaatcctagt tcttctggaa atgaagaagg
      601 tgttgtaaaa gcaatagaag agtcttttga aaaattaggt tttgatagtt ggtcaagaga
      661 tagatatgga aatatagtag gatgtataaa aggtaacaag ccaggtaaga aaatattatt
      721 tgatggacat atagatacag ttccagttcc agatgcaagt aaatggagtg ttcctccttt
      781 tgaaggaaaa atagttgatg gaaagatata tggtagagga acttctgaca tgaaaggtca
      841 atatactgca atgatgtctg ctgtagcgta ttttgctaaa gacactaata gagattttgc
      901 tggagaacta tatgtagcag gtgttgtaca tgaagaaata tttgaaggtg tttcggctag
      961 agagataagt aaggctgttc aacctgacta tgttgtaata ggtgagtctt cagagttaaa
     1021 cttaaagatt ggtcagagag gtagaggaga aatagtagta gaaacttttg gtaaaccagc
     1081 tcactctgct aatccagaaa aaggt
//
LOCUS       DAEORM030000160         1053 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.168, whole genome shotgun sequence.
ACCESSION   DAEORM030000160 DAEORM030000000
VERSION     DAEORM030000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1053)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1053)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 1053)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1053
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.168"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            complement(<1..271)
                     /locus_tag="KRH23_003859"
     CDS             complement(<1..271)
                     /locus_tag="KRH23_003859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHS5227122.1"
                     /translation="MQDVKEKVKQDYLKGMKQKEISAKYDISLNTLKSWIKRYNWANE
                     KKKGAPKNKRGAPIGNKNATGPPGNKNAEKFGFFSKYLPEETRELI"
     gene            complement(442..699)
                     /locus_tag="KRH23_003860"
     CDS             complement(442..699)
                     /locus_tag="KRH23_003860"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5227123.1"
                     /translation="MNDYKEKTEPKLNILVQSKVDILCSNSSTMNGVDTSIDIKLSLD
                     NRVIGNLTNEDIKKEISTSFNKCLKEIDKKICSKEVINKLI"
     gene            complement(746..943)
                     /locus_tag="KRH23_003861"
     CDS             complement(746..943)
                     /locus_tag="KRH23_003861"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5227124.1"
                     /translation="MSNLREKIIKELNEFNIKADNDFLEYAVEHIKKFMNEGIADEEL
                     LIRGVVLGASYVVNIENKDLD"
BASE COUNT          329 a          172 c          110 g          442 t
ORIGIN      
        1 gtattaattc cctagtttct tcaggtagat attttgagaa gaaaccaaac ttttcagcat
       61 ttttatttcc aggaggacca gtggcatttt tattacctat gggtgcacct cttttatttt
      121 taggtgcacc cttctttttc tcattagccc aattgtatct ttttatccat gactttaaag
      181 tatttaaact aatgtcatac tttgctgata tttccttttg tttcatacct tttaggtaat
      241 cttgttttac tttttctttc acatcttgca caccaccacc tcgtttgttt gtcgttttgg
      301 gaataaaaaa gaactcttgt tagagtctat gtatctaatt aaattacatt gatttattgc
      361 aaccttttta ttctggaagt ttagataaag aattaattat agaaaaagtt caagaacaac
      421 taatttcttc aattgaggaa atcaaatcag cttattaatt acttctttgc tacaaatttt
      481 tttatcaatt tcttttaaac acttattaaa agatgttgat atttcttttt ttatgtcttc
      541 attagttaaa ttgccaataa ctctattatc taaagaaagt tttatatcaa ttgaagtgtc
      601 tactccattc atagtagagc tattagaaca taagatatca actttagact ggactaaaat
      661 atttaatttt ggttcagttt tttctttata atcattcata atttattctc cttttaattt
      721 attgtataaa aaaaagacct agaaattaat ctaagtcttt attttctata ttaactacat
      781 aacttgctcc aagcacaact cctcttatta ataactcttc atcagctata ccttcattca
      841 taaacttttt aatgtgttca actgcatatt ctaaaaaatc attatctgct tttatattaa
      901 attcatttag ttcttttatt atcttttctc ttaaattact catttatcat actcctgtaa
      961 aaaaataaaa gactaagctt accctcactt agccttttta aatagggaga tacatatatt
     1021 atgtcgcaag ttctaagaat cgaacttaga tta
//
LOCUS       DAEORM030000161         1008 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.169, whole genome shotgun sequence.
ACCESSION   DAEORM030000161 DAEORM030000000
VERSION     DAEORM030000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1008)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1008)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 1008)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1008
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.169"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            <1..786
                     /locus_tag="KRH23_003862"
     CDS             <1..786
                     /locus_tag="KRH23_003862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain-containing protein"
                     /protein_id="HHS5227125.1"
                     /translation="GLHSYLISKPDHWKIYVNDLCKRSKNGRDATANILKELIENGYI
                     TRKPCRDSNTNKMLGGYDYEVYEIPLENPQKLKSRKTDFPETGFPGNRVSRKPENTEV
                     VSNDFKVNNDITTIVINEQSNKDKTTYIKKYFEKYIGVITPNNFIELMSYLDDGMEAD
                     VIIRAIDEAIANGVKNYKYVKTILNNWIEAGVKTNLELTEYQNEFERKKKNKQDKKQS
                     NSKAVNTPNVSKNKFHNFNETFTQYSPDELDDIIKKSQKVKFK"
BASE COUNT          429 a          122 c          187 g          270 t
ORIGIN      
        1 ggtttacatt catatctgat tagtaagccc gaccactgga aaatctatgt taatgacctt
       61 tgcaagagaa gtaaaaatgg aagagatgct acagcaaata ttttaaaaga acttatagaa
      121 aatggatata taacaagaaa accttgtaga gattctaata ctaataaaat gcttggaggg
      181 tatgattatg aagtatatga gataccactt gaaaatcctc agaagctaaa atcccgaaaa
      241 actgatttcc cggaaaccgg atttcccgga aaccgggttt ctcggaaacc ggaaaacacg
      301 gaagtagtaa gtaatgactt taaagtaaat aatgatatta ctactattgt tattaatgaa
      361 caatccaata aagacaaaac cacctacata aaaaaatact ttgaaaaata tataggtgtg
      421 attactccta ataactttat agagttaatg agttacttag atgatggaat ggaagctgat
      481 gtaattataa gagctattga tgaagcaata gcaaatggag ttaagaatta taagtatgta
      541 aagacaatat taaataattg gatagaagca ggtgtaaaaa ctaatttaga acttacagag
      601 tatcaaaatg agtttgagag gaagaaaaag aataaacagg ataagaagca gtctaatagt
      661 aaagctgtga atactcctaa tgtgagtaaa aataagtttc ataacttcaa tgaaacattt
      721 actcaatatt cacctgacga actagatgac ataattaaga aaagccaaaa ggttaaattt
      781 aaataaaatt aaacttctag gaagtaaata tcaatatatt gcttcctaga aaggggaggt
      841 ataaatggcg agaatatatg cacaaagaag tggttcttta aatgaacaag atagattgga
      901 attattaaga ttacttggga aagctggata tacagtaaag attgctagag agaagcaaaa
      961 tagcaagaca acttatactt actttgttga gtatacagaa gagcaaga
//
LOCUS       DAEORM030000162          944 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.170, whole genome shotgun sequence.
ACCESSION   DAEORM030000162 DAEORM030000000
VERSION     DAEORM030000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 944)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 944)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 944)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..944
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.170"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            complement(137..820)
                     /locus_tag="KRH23_003863"
     CDS             complement(137..820)
                     /locus_tag="KRH23_003863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YoaK family protein"
                     /protein_id="HHS5227126.1"
                     /translation="MTSKSQMSESFFLCSLLAITGGFLDIYTYVVRGKVFANAQTGNI
                     VLFGLNIAEGNVKESFYYLIPILAFMLGVFIAEKIRKYFTNNKTKIHWRQVIIIIEMI
                     TILIVSFIPRGRFNMFVNVAISFICSMQVESFRKVNGNSFATTMCTGNLRSATETLFH
                     YIHTKNIFMIKKSLQYYAIIIFFISGAILGTFFTKIFVEKSILICFFILAVVFGIMFI
                     NKDDSFNEN"
BASE COUNT          371 a          149 c           75 g          349 t
ORIGIN      
        1 ttactatact taaaatactt ctattaactt atacattgct tactatattt taaattcttt
       61 aattaatcta tacaatattt gctatatata aagtatatca aataacagct tcattttttt
      121 gtaaatttac agaaagttaa ttttcattaa atgaatcatc tttattgata aacataattc
      181 caaagaccac tgccaaaata aaaaaacata ttagtattga tttttccacg aaaatttttg
      241 taaaaaaagt tcctaaaata gctccagata taaagaatat aataatagca taatactgta
      301 aactcttttt tatcataaaa atattcttag tatgtatata atgaaataaa gtttctgtag
      361 cacttcttaa atttccagta cacattgtcg ttgcaaaact attcccattt acttttctaa
      421 aactctctac ttgcattgaa caaataaaag aaatagcaac atttacaaac atattaaatc
      481 ttcctctagg aataaatgaa acaataagta ttgtaatcat ttcaattata atgataacct
      541 gacgccaatg aatctttgtc ttattatttg taaaatactt tcttatcttc tcggctataa
      601 atacacctaa cataaatgcc aaaataggaa tcaaataata aaatgattcc tttacattac
      661 cttctgctat attaagccca aataaaacta tatttccagt ttgtgcatta gcaaagactt
      721 tacctcttac cacataagta taaatatcca aaaatcctcc tgttattgcc aacaaagaac
      781 ataaaaagaa tgattcagac atctgactct tgcttgtcat atataaacct ctcgctttct
      841 aatgatagat acaaaatcaa aatcatttta gattctattt ttcattgata taaaaaaatt
      901 atttatattt aaatattgtc tatatttata catcatttat attt
//
LOCUS       DAEORM030000163          941 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.171, whole genome shotgun sequence.
ACCESSION   DAEORM030000163 DAEORM030000000
VERSION     DAEORM030000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 941)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 941)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 941)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..941
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.171"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            331..>941
                     /locus_tag="KRH23_003864"
     CDS             331..>941
                     /locus_tag="KRH23_003864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HHS5227127.1"
                     /translation="MIKLTIEEYKNKYFTGNKIVLSINSFDNKELYYHETENILNLIN
                     EIDKLTSSKIFKTIEDKNDLALESYYSSVIEGAFSTRKIAKSIIRGKMKPSNKSEYMI
                     YNNHRALEYGLDNLDKLYSHKFIYDLHHILGENCLDSEEYEYRTEKVYVCDSKGEIIH
                     TGLEPLKIYDFMSKLIDFMKNSKVSNLIKSAIIHFYFVYVHPF"
BASE COUNT          408 a           75 c          121 g          337 t
ORIGIN      
        1 taaaatatta agtaatttca aaaaaatata aatttattta atttaattaa aatattataa
       61 catattagtt acatattaaa atatataatc gagatattgt taagacattg tcgagatatt
      121 ataatatata actaatgtat tataaataat agttgtaaac ttcctgtaac atatatttta
      181 aatgcttatt cttaaatttt tgcattattt attaaaattt attatgcttt aacgctaaat
      241 tgagtttgat aattataaaa caaataatca aaaatagtgt aaaaattaat actttttgtt
      301 aatattaata gataaagata atctaaggtg gtgattaaac tgacaataga agaatacaaa
      361 aacaaatact ttactggaaa taaaatcgta ctttctataa atagttttga taataaagaa
      421 ctatactatc atgaaactga aaatatatta aatttaataa atgaaataga taaattaaca
      481 tcaagtaaga tatttaaaac aatagaagat aaaaatgatt tggcactaga gtcttattat
      541 tctagtgtaa tagaaggtgc tttttcaact agaaagattg caaaatctat aattagagga
      601 aagatgaaac ctagtaataa aagtgaatat atgatttaca ataatcatag agccttagaa
      661 tatggattag ataacttaga taaattgtat agtcacaaat ttatatatga tttgcatcat
      721 atattgggtg aaaactgctt ggattcagaa gaatatgagt atagaactga aaaagtatat
      781 gtatgtgatt caaaaggtga gattatacat acagggcttg aacctttgaa gatatatgac
      841 tttatgagta aattaataga ttttatgaaa aatagcaaag taagtaattt aattaaaagt
      901 gctataattc atttttactt tgtatatgtt catcctttta g
//
LOCUS       DAEORM030000164          814 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.172, whole genome shotgun sequence.
ACCESSION   DAEORM030000164 DAEORM030000000
VERSION     DAEORM030000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 814)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 814)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 814)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..814
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.172"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            complement(<1..>814)
                     /locus_tag="KRH23_003865"
     CDS             complement(<1..>814)
                     /locus_tag="KRH23_003865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="baseplate J/gp47 family protein"
                     /protein_id="HHS5227128.1"
                     /translation="DTFDKREGSIIYNALAPVAIELTETYIAMDELLDQTFVDTASYY
                     YLEKRCKERGITPLEATNTIAKGVFNIDIPIDSRFNLGEYNYVAIERISEGIYKMKCE
                     TAGPIFELGQLIPIEYIDKLETAELTEILINGEDEESEDSLRQRYYDSLNSQSFGGNM
                     QNYKDEVNKIQDVGGVKVYPVWDGGGTVKLVIINSNFKVPSEDLVNLVQEEIDPIGHQ
                     GQGLGLAPIGHKVTVTGVVSTTINISAEITYKNGYTWENIKSIAEEAIDDYLN"
BASE COUNT          228 a          169 c           99 g          318 t
ORIGIN      
        1 catttaaata gtcgtctatt gcttcttctg caattgattt tatattctcc caagtgtagc
       61 catttttgta tgttatctct gctgatatat ttatagttgt acttacaaca cctgtaacag
      121 taactttatg ccctattggt gctaatccta agccttgtcc ttgatgtcca attgggtcaa
      181 tttcttcttg cactaaatta actaaatcct ctgatggtac tttgaaatta gagttaatta
      241 ttactaactt aacagttcct ccaccgtccc acacaggata aaccttaact cctccaacat
      301 cttgtatttt gttaacttca tctttataat tttgcatatt tccaccaaag ctctgtgaat
      361 ttaggctatc ataatatctt tgtcttaaac tatcctcact ctcttcatct tctccattta
      421 tcagtatttc tgtcagttct gctgtttcta atttgtctat atattcgata ggtattagtt
      481 gtcccaactc aaaaataggt cccgcagtct cacatttcat cttatatata ccttcagata
      541 ttctctcaat tgctacatag ttatattctc ctagattaaa cctagaatca ataggaatat
      601 ctatgttaaa aactcctttt gcaattgtat tagtggcttc aagtggtgta atacctctct
      661 ctttacatct cttctctaaa taataataac tagcagtatc tacgaatgtt tggtctagta
      721 attcatccat agcaatgtat gtttctgtaa gttctatagc aacaggagca agagcattat
      781 atattataga accttccctt ttatcaaaag tatc
//
LOCUS       DAEORM030000165          787 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.173, whole genome shotgun sequence.
ACCESSION   DAEORM030000165 DAEORM030000000
VERSION     DAEORM030000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 787)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 787)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 787)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..787
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.173"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            complement(<1..>787)
                     /locus_tag="KRH23_003866"
     rRNA            complement(<1..>787)
                     /locus_tag="KRH23_003866"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          172 a          238 c          182 g          195 t
ORIGIN      
        1 cgtccatccc ggtcctctcg tactaaggac aggtcttctc aaatttccta cgcctgcgac
       61 ggatagggac cgaactgtct cacgacgttc tgaacccagc tcgcgtacca ctttaatggg
      121 cgaacagccc aacccttggg acctactaca gccccaggat gtgatgagcc gacatcgagg
      181 tgccaaacct ccccgtcgat gtggactctt gggggagata agcctgttat ccccagggta
      241 gcttttatcc gttgagcgat ggcccttcca cgcagaacca ccggatcact aagtccgatt
      301 ttcatccttg ctcgacctgt atgtcttgca atcaagctct cttttgcctt tacactctac
      361 gtacgatttc cgaccgtact gagagaacct ttgagcgcct ccgttacctt ttgggaggcg
      421 accgccccag tcaaactgcc cacctgacag tgtcccaaga ccagattcat ggcctatggt
      481 tagagtccca gtactacaag ggtggtatcc caaggatggc tccgccaaaa ctggcgtcct
      541 ggtttcaaag cctcccacct atcctgtaca tgtagtacca agacccaatg tcaagctaca
      601 gtaaagctcc atggggtctt tccgtcctgt cgcaggtatc cggcatcttc accggaatta
      661 caatttcacc gagtctgttg ttgagacagt gcccaaatcg ttacgccttt cgtgcgggtc
      721 ggaacttacc cgacaaggaa tttcgctacc ttaggaccgt tatagttacg gccgccgttt
      781 actgggg
//
LOCUS       DAEORM030000166          753 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.174, whole genome shotgun sequence.
ACCESSION   DAEORM030000166 DAEORM030000000
VERSION     DAEORM030000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 753)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 753)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 753)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..753
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.174"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            <1..>753
                     /locus_tag="KRH23_003867"
     rRNA            <1..>753
                     /locus_tag="KRH23_003867"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          207 a          156 c          227 g          163 t
ORIGIN      
        1 tttaactgag cgttcagtta cttgacgtag acccgaaacc gggcgaccta cccatgagca
       61 ggatgaagcg aaagtaaaat ttcgtggagg tccgaaccca cgagcgttga aaagctcggg
      121 gatgacttgt gggtagcggt gaaattccaa tcgagcccgg agatagctgg ttctccccga
      181 aatagcttta gggctagcct caaggtgaga gatacggagg tagagcactg aatgtcctag
      241 ggggtattgc acctaccgaa gactatcaaa ctccgaatgc cgtcatctta tacttgggag
      301 tcagactgtg ggtgataaga ttcatagtcg aaagggcaac agcccagatc gtcagctaag
      361 gtccctaaat gtaagttaag tggtaaagga tgtgggattg cacagacaac caggatgttg
      421 gcttagaagc agccactcat tcaaagagtg cgtaatagct cactggtcga gtgatcctgc
      481 gccgaagatt tccggggcta aaacttacta ccgaagctac ggcatcagta atgatgggta
      541 ggggagcttc ccatacgggt tgaagcatga ccgtaaggac atgtggacag tatgggagtg
      601 agaatgttgg catgagtagc gagatgtggg tgagaatccc acaggccgta aacccaaggt
      661 ttccagggga aggttcgtcc gccctgggtt agtcgggacc taagctgagg ccgaaaggcg
      721 taggtgatgg acaacaggtt gatattcctg tac
//
LOCUS       DAEORM030000167          733 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.175, whole genome shotgun sequence.
ACCESSION   DAEORM030000167 DAEORM030000000
VERSION     DAEORM030000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 733)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 733)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 733)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..733
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.175"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            129..599
                     /locus_tag="KRH23_003868"
     CDS             129..599
                     /locus_tag="KRH23_003868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HHS5227129.1"
                     /translation="MKYQVSLLAVKDIEVSKKFYKELFEQEIELDLGKNVTFKGGFAI
                     QEDFAWLTGINPDTIIQKSNNMELYFEVDDFDEFIEKLNYYKDVEFVHKPLKHEWQQR
                     VVRIYDPDKHIIEIGESMEVIARRYLSEGYSVEETSKIIQHPIEFVKQCENSKE"
BASE COUNT          334 a           56 c          127 g          216 t
ORIGIN      
        1 aaaagtgtta atagaagata ctaaaaaagt aaaaataaag gattaataaa aggtactgaa
       61 gagatagaga aaaaaatgtt aatagaagat actgaaaaaa tagaaataaa aaattaggag
      121 gaaaatttat gaaatatcag gtttcattat tagcagtgaa ggatattgaa gtatcaaaaa
      181 aattttacaa agaattattt gagcaagaaa ttgaattgga cttaggtaaa aatgtaacat
      241 ttaaaggagg atttgctata caagaagact tcgcatggct tacagggatt aatccagata
      301 caattataca aaaatcaaat aatatggaac tttattttga ggttgatgat tttgacgaat
      361 ttattgaaaa actcaattat tataaagatg tagagtttgt ccataagcca ctaaaacatg
      421 aatggcaaca aagagtagtg cgtatttatg acccagataa gcatattatt gagataggag
      481 agtctatgga agttatagct agaagatatt tatctgaggg atattctgta gaagaaactt
      541 ctaaaataat tcaacatcca attgaatttg taaagcagtg tgaaaatagt aaggaatgat
      601 tgtttaaatt ataattattt agtagaaatt aattgtagta gaactaattc aagataatat
      661 ataggactag tatttgacaa atgtcataaa ttaaattaaa ataaagaaaa tattaataaa
      721 gaaaaaataa ata
//
LOCUS       DAEORM030000168          700 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.176, whole genome shotgun sequence.
ACCESSION   DAEORM030000168 DAEORM030000000
VERSION     DAEORM030000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 700)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 700)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 700)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..700
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.176"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            <1..>700
                     /locus_tag="KRH23_003869"
     CDS             <1..>700
                     /locus_tag="KRH23_003869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HHS5227130.1"
                     /translation="LYLNASNKGVEWLHPYINRKGEFKYVIIPAEEAIPIWDSKRQRE
                     LVAFIRFYYIEDIDGNKIKRVEYYTENDVTYFIERGNSFIQEFLYDEYGKMTDVQEGH
                     FRINNKEQGWGKVPFIPFKNNEKCVSDLNFYKSLIDIYDNNISTLADNLDEIQEVIYV
                     LKEYPGTSLQEFIDNIRYYKSIKVDGGGGVDKLEINIPVEAKKELLDRLEKNIIIFGQ
                     GVNPESQNTGDKSGV"
BASE COUNT          291 a           65 c          131 g          213 t
ORIGIN      
        1 actatatctc aatgctagta ataaaggggt tgaatggtta catccatata ttaatagaaa
       61 aggtgagttt aaatatgtaa taattccagc tgaagaagca attcctattt gggatagtaa
      121 aagacagagg gaattagttg catttattag gttttattat attgaagata tagatggaaa
      181 taaaataaaa agagttgagt actacacaga aaatgacgta acttacttta ttgaaagagg
      241 taatagtttt attcaagaat ttttatatga tgaatatgga aaaatgactg atgtacaaga
      301 aggtcatttt agaataaata acaaagaaca gggatggggt aaagttccat ttataccttt
      361 taaaaataat gaaaagtgcg tatcagattt aaatttctat aaatcattaa tagatatata
      421 tgacaataat atttctacac tagcagataa cttagatgaa atacaagagg ttatttatgt
      481 attaaaagaa tatccaggaa caagtctaca agagtttata gataatataa gatactataa
      541 atcaattaaa gtagatggtg gaggtggagt tgataaacta gagataaata taccagttga
      601 agctaaaaag gagcttcttg atagattgga aaagaatata attatctttg gtcaaggagt
      661 taatccagaa tctcaaaaca caggtgacaa atcgggtgta
//
LOCUS       DAEORM030000169          664 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.177, whole genome shotgun sequence.
ACCESSION   DAEORM030000169 DAEORM030000000
VERSION     DAEORM030000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 664)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 664)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 664)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..664
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.177"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            complement(<1..>664)
                     /locus_tag="KRH23_003870"
     rRNA            complement(<1..>664)
                     /locus_tag="KRH23_003870"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          152 a          191 c          151 g          170 t
ORIGIN      
        1 gatccagccg caccttccga tacggctacc ttgttacgac ttcaccccag ttattgattc
       61 caccttcgac gacttcttcc aaaaggttag ataatcggct tcgggcgtct ccaactcccg
      121 tggtgtgacg ggcggtgtgt acaagacccg ggaacgcatt caccgcagca ttctgatctg
      181 cgattactag taactccagc ttcatgtagg cgagtttcag cctacaatcc gaactgagag
      241 tagctttaag ggattagctc caccttacgg cttggcaacc ctctgtacta cccattgtag
      301 cacgtgtgta gccctaagca taaggggcat gatgatttga cgtcatcccc accttcctcc
      361 aggttatccc tggcagtctc tctagagtgc ccaacttaat gatggcaact aaagacaagg
      421 gttgcgctcg ttgcgggact taacccaaca tctcacgaca cgagctgacg acaaccatgc
      481 accacctgtc accaatgtcc ccgaagggaa ctctccgatt aaggagatgt cattgggatg
      541 tcaagcttag gtaaggttct tcgcgttgct tcgaattaaa ccacatgctc cgctacttgt
      601 gcgggtcccc gtcaattcct ttgagtttca ctcttgcgag cgtacttccc aggcggagta
      661 ctta
//
LOCUS       DAEORM030000170          577 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.178, whole genome shotgun sequence.
ACCESSION   DAEORM030000170 DAEORM030000000
VERSION     DAEORM030000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 577)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 577)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 577)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..577
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.178"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            <1..>577
                     /locus_tag="KRH23_003871"
     rRNA            <1..>577
                     /locus_tag="KRH23_003871"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          154 a          121 c          190 g          112 t
ORIGIN      
        1 caggatggac ccgcgtctga ttagctagtt ggtaaggtaa cggcttacca aggcgacgat
       61 cagtagccga cctgagaggg tgatcggcca cattggaact gagacacggt ccaaactcct
      121 acgggaggca gcagtgggga atattgcaca atgggcgaaa gcctgatgca gcaacgccgc
      181 gtgagtgatg aaggccttcg ggtcgtaaaa ctctgtcctc aaggaagata atgacggtac
      241 ttgaggagga agccccggct aactacgtgc cagcagccgc ggtaatacgt agggggctag
      301 cgttatccgg atttactggg cgtaaagggt gcgtaggcgg tctttcaagt caggagtgaa
      361 aggctacggc tcaaccgtag taagctcttg aaactgggag acttgagtgc aggagaggag
      421 agtggaattc ctagtgtagc ggtgaaatgc gtagatatta ggaggaacac cagttgcgaa
      481 ggcggctctc tggactgtaa ctgacgctga ggcacgaaag cgtggggagc aaacaggatt
      541 agataccctg gtagtccacg ctgtaaacga tgagtac
//
LOCUS       DAEORM030000171          568 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.179, whole genome shotgun sequence.
ACCESSION   DAEORM030000171 DAEORM030000000
VERSION     DAEORM030000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 568)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 568)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 568)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..568
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.179"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            <1..551
                     /locus_tag="KRH23_003872"
     CDS             <1..551
                     /locus_tag="KRH23_003872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ERF family protein"
                     /protein_id="HHS5227131.1"
                     /translation="KSQFNSFGKYNYRSCEDILEGLKPILKEEKALVILDDNIVQIGN
                     RFYVEATATLIDAETGEKVSTKALAREDETKKGMDLAQVTGSVSSYARKYALNGLFCI
                     DDTKDSDATNKHGNEQKKKEVNESELNTLYSLGESIEKDKNRVDSEVYKKFGKLAVDL
                     TKQEYEKVLNGYKSILEKQKQE"
BASE COUNT          247 a           45 c          125 g          151 t
ORIGIN      
        1 ctaaaagtca atttaatagc tttggtaaat acaactatag gagttgtgag gatatactag
       61 aaggtttaaa acctattcta aaggaagaaa aagcattagt tatattggat gataatattg
      121 ttcagatagg aaatagattt tatgtagaag ctacagcaac tttaatagat gcagaaacag
      181 gagagaaagt atctacaaag gcattagcta gagaagatga aactaaaaaa ggtatggatt
      241 tagcacaagt aactggaagt gtatcaagtt atgcaagaaa gtacgcttta aatggattat
      301 tttgtattga tgatacaaaa gatagtgatg caacaaataa acatggaaat gagcagaaaa
      361 aaaaagaagt taatgagagt gaattaaata cactatattc gctaggagaa tctatagaaa
      421 aagataaaaa tagagttgat agtgaagtat ataagaagtt tggaaagtta gcagtagatt
      481 tgactaagca agagtatgag aaagttttaa atggatataa gagcatttta gagaagcaaa
      541 aacaagagta ggtgatagta ttggggat
//
LOCUS       DAEORM030000172          563 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.180, whole genome shotgun sequence.
ACCESSION   DAEORM030000172 DAEORM030000000
VERSION     DAEORM030000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 563)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 563)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 563)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..563
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.180"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            complement(<1..372)
                     /locus_tag="KRH23_003873"
     rRNA            complement(<1..372)
                     /locus_tag="KRH23_003873"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          159 a          133 c           90 g          181 t
ORIGIN      
        1 aggactatta ccttctgtgg tgggtctttc caaacctctt caattacgat acctcttcgt
       61 tatgatatgt ccgcaacccc aataaagaaa actttattgg tttgggctaa tccgcgttcg
      121 ctcgccgcta cttacggaat cgaatttctt tctcttcctt caggtactta gatgtttcag
      181 ttccctgagt tcccctcatt aagctatgta ttcacttaat gatacttaga cattactcta
      241 agtgagtttc ctcattcgga aatcttcgga tcaaagttta cgtgcaactc cccgaagctt
      301 atcgcagctt atcacgtcct tcatcggctc ctagtgccaa ggcatccgcc ctgcaccctt
      361 aataacttga ccagttaaaa aggtttgata gattagaagc tatcaacttc gataatttta
      421 aaaagttatc agctttatat attacaaatt agatgtcata tcactaaata tatatatgca
      481 gttttcaaag tgctaaagca cggcgccaac gaataaattc tgttgcttaa aagtgctaat
      541 gcaccacgtc aacgaacaac ctt
//
LOCUS       DAEORM030000173          509 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.181, whole genome shotgun sequence.
ACCESSION   DAEORM030000173 DAEORM030000000
VERSION     DAEORM030000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 509)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 509)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 509)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..509
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.181"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            127..>509
                     /locus_tag="KRH23_003874"
     CDS             127..>509
                     /locus_tag="KRH23_003874"
                     /inference="COORDINATES: protein motif:HMM:NF018653.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HHS5227132.1"
                     /translation="MTNTIYIHQPEKAFSFTRLPNFLFEAPTFKPLSNEAKVLYAFIL
                     RRTELSRKNGWADDCGRIFLYYPICEVVTLLHCGRQKAVNTLRELQYAGLVEIQKQGC
                     GKPNRIFPKSYEAVPNTDFKKSRSGT"
BASE COUNT          135 a          140 c          126 g          108 t
ORIGIN      
        1 gctgtggaca gttaggagcg aaaaaagcct tgatttatca ggctttgcaa gccccaaacc
       61 ggggcaggtg gtataaagta tcgcccgccc cggaaaacgg gcttctaacc gtccacaaaa
      121 cacgatatga caaacacgat ttacattcat cagccggaaa aggcgttcag cttcacccgg
      181 ctcccaaatt tcctctttga agcccccaca ttcaagcccc tgtccaacga ggcaaaggtt
      241 ctgtacgcct ttatcctgcg ccggacagag ttatcccgca agaatgggtg ggcggatgac
      301 tgcggacgga ttttcctgta ttaccctatc tgtgaagtgg tcacactgct ccattgtggg
      361 cggcagaaag cggtgaatac cctgcgggaa ctgcaatacg ccggactggt ggagatccag
      421 aagcagggct gtggaaaacc caaccgcatt ttcccaaaat cctatgaagc ggttccaaac
      481 accgacttta agaaatcccg ttctggtac
//
LOCUS       DAEORM030000174          452 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.182, whole genome shotgun sequence.
ACCESSION   DAEORM030000174 DAEORM030000000
VERSION     DAEORM030000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 452)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 452)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 452)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..452
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.182"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            <1..>452
                     /locus_tag="KRH23_003875"
     CDS             <1..>452
                     /locus_tag="KRH23_003875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="EF-Tu/IF-2/RF-3 family GTPase"
                     /protein_id="HHS5227133.1"
                     /translation="QDEVELVGLTEAPRKVVVTGVEMFRKLLDQAQAGDNIGALLRGV
                     QRNEIERGQVLAKTGSVKAHTKFTAEVYVLKKEEGGRHTPFFDGYRPQFYFRTTDVTG
                     ACKLPEGIEMVMPGDNVTMEVDLINSIVVEEGLRFSIREGGRTVASGV"
BASE COUNT          193 a           57 c          111 g           91 t
ORIGIN      
        1 acaagacgaa gtagaattag taggattaac agaagcacca agaaaagtag tagtaacagg
       61 agtagagatg ttcagaaaat tattagacca agcacaagca ggggataata taggagcatt
      121 attaagagga gtacaaagaa acgagataga aagaggacaa gtactagcaa agactggatc
      181 agtaaaggca cacacaaagt ttacagcaga agtatatgta cttaaaaaag aagagggtgg
      241 aagacataca ccattctttg atggatatag accacaattc tatttcagaa caacagacgt
      301 aacaggagct tgtaagttac cagaaggaat agagatggta atgcctggag ataacgtaac
      361 aatggaagta gacttaataa actcaatagt tgtagaagag ggattaagat tctcaataag
      421 agaaggtgga agaacagtag cttcaggagt tg
//
LOCUS       DAEORM030000175          438 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.183, whole genome shotgun sequence.
ACCESSION   DAEORM030000175 DAEORM030000000
VERSION     DAEORM030000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 438)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 438)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.183"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            <1..>438
                     /locus_tag="KRH23_003876"
     CDS             <1..>438
                     /locus_tag="KRH23_003876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase large subunit"
                     /protein_id="HHS5227134.1"
                     /translation="RAMKGSAGSGKSVNVAQDYILKLGDKKYQGANLLVVRKSEATHK
                     YSTYAELTGAINRIYGKQADKYWKTTLNPLEIKSKVTGNSIIFRGVNDAKQREKLKSI
                     NFSKGKLTWVWCEEATELMESDIDILDDRLRGILTNPNLYYQMT"
BASE COUNT          179 a           55 c           86 g          118 t
ORIGIN      
        1 agagcaatga aaggttcagc agggagtgga aaatctgtta atgtagcaca agactatata
       61 ctaaagttag gagataagaa gtatcaagga gctaatctat tagtagttag aaagtcagaa
      121 gctacacata agtattcaac gtatgcagag cttacaggag ctataaatcg tatttatggt
      181 aaacaagctg ataagtattg gaaaactact ttaaatcctt tagaaattaa gagtaaagtt
      241 actggtaact ctataatttt cagaggagtt aatgatgcaa aacaaagaga aaaattaaaa
      301 tcaattaact tctcgaaagg aaaattaaca tgggtttggt gtgaagaagc tacagaactt
      361 atggaaagtg acatagacat actagatgac cgtttaagag gtattttaac taatcctaac
      421 ctatactatc aaatgaca
//
LOCUS       DAEORM030000176          430 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.184, whole genome shotgun sequence.
ACCESSION   DAEORM030000176 DAEORM030000000
VERSION     DAEORM030000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 430)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 430)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 430)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..430
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.184"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            90..>430
                     /locus_tag="KRH23_003877"
     CDS             90..>430
                     /locus_tag="KRH23_003877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsid protein"
                     /protein_id="HHS5227135.1"
                     /translation="MAALNYAKEYSNVLAQAYPYTLNFGDLYATPNNGRYRWTGSKTI
                     EIPTISTTGRVDSNRDTIAVAQRNYDNAWEPKVLTNQRKWSTLVHPADINQTNYVASI
                     GNITKVYNEEQ"
BASE COUNT          182 a           61 c           77 g          110 t
ORIGIN      
        1 ccagggcaag agcctaagat aaatgatttt ggttttaatt ttactggggt aagacctcat
       61 gaaaataata ataaatagga ggaaataaaa tggcagcact aaattatgca aaagaatatt
      121 caaatgtttt agcacaagca tatccttata ctttaaactt cggggatttg tatgcaacac
      181 caaataatgg aagatataga tggactggtt ctaaaacaat agaaatacca actatatcta
      241 caactggaag agtagattca aacagagata caatagcagt agctcaaaga aactatgata
      301 atgcttggga acctaaggta ttaactaatc aaaggaaatg gtcaacattg gttcatccag
      361 cagatataaa ccaaactaat tatgtggctt caataggcaa tataacaaaa gtatataatg
      421 aggaacaaaa
//
LOCUS       DAEORM030000177          355 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.185, whole genome shotgun sequence.
ACCESSION   DAEORM030000177 DAEORM030000000
VERSION     DAEORM030000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 355)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 355)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 355)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..355
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.185"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            45..>355
                     /locus_tag="KRH23_003878"
     CDS             45..>355
                     /locus_tag="KRH23_003878"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5227136.1"
                     /translation="MVEKYPDLERGESASRTGRKHIPTRLFKQAVSLSRQARAIEATL
                     DGINPLNAGKKKEEALSMLKKWFPQMENFSGQLKKYKVTINDLLAENEKLEARAKASE
                     KG"
BASE COUNT          107 a           87 c          105 g           56 t
ORIGIN      
        1 accgggcaaa cctgacgaag tggcaggacg attttcacgc ctatatggtg gagaaatatc
       61 ctgacttgga gcgtggggag agcgccagca ggacaggccg gaagcatatc cccacccggc
      121 ttttcaaaca ggcggtttcc ctctcccggc aggcaagagc cattgaagcc acactggacg
      181 gcattaaccc gctgaacgcc ggaaagaaaa aagaggaagc cctctccatg ctgaaaaagt
      241 ggttcccgca gatggagaat ttctccgggc agttgaaaaa gtacaaggtc acaatcaatg
      301 acctgctggc ggagaatgag aagttggaag caagggcaaa ggccagcgaa aaagg
//
LOCUS       DAEORM030000178          348 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.186, whole genome shotgun sequence.
ACCESSION   DAEORM030000178 DAEORM030000000
VERSION     DAEORM030000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 348)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 348)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 348)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..348
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.186"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            92..319
                     /locus_tag="KRH23_003879"
     CDS             92..319
                     /locus_tag="KRH23_003879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HHS5227137.1"
                     /translation="MNSLLKEAIDELKNIHCGEVFLLKELFKGYEWNRLEMNIRLKLG
                     KLFLYEVVTNPNLNVEVINKNSAYQQMYKKK"
BASE COUNT          146 a           32 c           56 g          114 t
ORIGIN      
        1 accataataa ttcctttata atttgtttga ctatgtcaaa aattaccaat ataatgaaat
       61 taatgagttt atacaaattg gaggaaataa tatgaatagt ctgttaaaag aagcaataga
      121 tgaattaaaa aacatccatt gcggggaagt ttttttatta aaagaattgt tcaaaggcta
      181 tgaatggaac aggttggaga tgaatatcag attgaaatta ggaaaacttt ttttgtatga
      241 agtggtaact aatcccaatt taaatgtaga ggtcatcaat aaaaattctg cttatcagca
      301 aatgtataaa aaaaaatagt gacttaaatg tatataatag tataatct
//
LOCUS       DAEORM030000179          348 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.187, whole genome shotgun sequence.
ACCESSION   DAEORM030000179 DAEORM030000000
VERSION     DAEORM030000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 348)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 348)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 348)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..348
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.187"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
BASE COUNT          163 a           26 c           35 g          124 t
ORIGIN      
        1 ataattttta tattaaaaaa tatgaatgaa aatagtgggt tttataaaaa aacatattta
       61 gattttaaca tctcaaagga gttttcaaag ctaatatttc atttttaaat aaaaaaataa
      121 aatattagtt ttgatttctg gtttaaattg ggttataata aattgtcaaa ttatttatta
      181 atataaaata gactataaaa caagcaaaaa tcatactatt atacaaaaga ccttaaagat
      241 agaaaactac agaaagaagc caaaatgttt ttgaaaaaaa tgaaatttta ttgcaaaaaa
      301 atcaaaatga atttaactta atagttataa tctattttta gtgttaca
//
LOCUS       DAEORM030000180          335 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.188, whole genome shotgun sequence.
ACCESSION   DAEORM030000180 DAEORM030000000
VERSION     DAEORM030000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 335)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 335)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 335)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..335
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.188"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            complement(<1..307)
                     /locus_tag="KRH23_003880"
     CDS             complement(<1..307)
                     /locus_tag="KRH23_003880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009531558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid recombination protein"
                     /protein_id="HHS5227138.1"
                     /translation="MAQHAILRFEKHKGNPARPLEAHHERQKEQYASNPDIDTSRSKY
                     NFHIVKRSGRYYHFIQSRIEQAGCRTRKDSTRFVDTLITASPEFFKGKSPKEIQAFFQ
                     "
BASE COUNT           52 a           88 c           87 g          108 t
ORIGIN      
        1 tttggaagaa cgcctgtatc tcctttgggg atttcccctt aaaaaactcc gggctggcgg
       61 ttatcagcgt atcgacaaac cgtgtgctgt ccttgcgggt tcggcacccg gcctgctcga
      121 tacggctctg aatgaagtgg taatagcgtc ccgaccgctt gacgatatgg aagttgtatt
      181 tactccggct tgtgtcaatg tcggggttgc tggcgtattg ttctttctgt ctttcgtgat
      241 gggcttccag cggccttgcc gggttgccct tgtgcttctc aaaccgtaaa attgcgtgtt
      301 gtgccattct gctcctttcc ccattccttt cctat
//
LOCUS       DAEORM030000181          311 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.189, whole genome shotgun sequence.
ACCESSION   DAEORM030000181 DAEORM030000000
VERSION     DAEORM030000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 311)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 311)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 311)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..311
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.189"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
BASE COUNT          100 a           57 c           55 g           99 t
ORIGIN      
        1 attccccagt ttttccccag aaattcccac tttattccct actttctccc ctttttgatt
       61 aaaaaagcat gagataatag tattgtggaa ataaagattt ccctctcaaa acttaatatt
      121 tgactagggt ataagggatt gccctagtca ctacgaacag actaggcagg gcgtgaggac
      181 gctgttagtt caattctaac tatgttcaaa tattaatcaa cgtatacact aaaagtagag
      241 aaattgaggg caaaatttta tattttgtat cttaattcag aagtctaaaa atcgggtggg
      301 gcttggtaac c
//
LOCUS       DAEORM030000182          302 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.190, whole genome shotgun sequence.
ACCESSION   DAEORM030000182 DAEORM030000000
VERSION     DAEORM030000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 302)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 302)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 302)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..302
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.190"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            8..84
                     /locus_tag="KRH23_003881"
     tRNA            8..84
                     /locus_tag="KRH23_003881"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:42..44,aa:Pro,seq:tgg)
     gene            170..245
                     /locus_tag="KRH23_003882"
     tRNA            170..245
                     /locus_tag="KRH23_003882"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:203..205,aa:Trp,seq:cca)
BASE COUNT           78 a           61 c           84 g           79 t
ORIGIN      
        1 tcaaaaacga ggtgtagcgc agtttggtag cgcacatggt ttgggaccat ggggccgggg
       61 gttcgagtcc cttcacctcg accaacttaa gcttttagtt cagttggtta gagtgcccaa
      121 ctcatggcca gtaattctag ggtttgagtc catgaaggtt attcttcata ggggtgtagc
      181 tcagttggta gagcgtcggt ctccaaaacc gtgcgccggg ggttcgagtc cctccacccc
      241 tgccaaataa aaaggacttg aaaaaagttg gattttagag tagtataaga tagtaaataa
      301 ga
//
LOCUS       DAEORM030000183          285 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.denovo.191, whole genome shotgun sequence.
ACCESSION   DAEORM030000183 DAEORM030000000
VERSION     DAEORM030000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 285)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 285)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 285)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..285
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.denovo.191"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            <1..>285
                     /locus_tag="KRH23_003883"
     rRNA            <1..>285
                     /locus_tag="KRH23_003883"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT           88 a           57 c           83 g           57 t
ORIGIN      
        1 ggatgtgatg gggagcgaaa tttagtagcg aagtagctga tttcacactg tcaagaaaag
       61 tctctatcga ggttaaaggt acccgtaccg caaaccgaca caggtgggtg aggagagtat
      121 cctaaggcca gcgagagaac tgttgttaag gaactcggca aaatgacccc gtaacttagg
      181 gataaggggt gccaccatca ggtggccgca gagaataggc ccaagcgact gtttaccaaa
      241 aacataggtt tctgctaagt cgcaagacga tgtataggag ctgac
//
LOCUS       DAEORM030000184        18663 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.guided.068, whole genome shotgun sequence.
ACCESSION   DAEORM030000184 DAEORM030000000
VERSION     DAEORM030000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18663)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18663)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 18663)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18663
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.guided.068"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            82..798
                     /locus_tag="KRH23_003884"
     CDS             82..798
                     /locus_tag="KRH23_003884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5227139.1"
                     /translation="MILIVILSIFIIASINIIILGKENIRDIVIPLTLFIVSDFLFLC
                     GNIICRGGVMLLFIGLFAIPLMLIAFIWICVHMIKLYYKKDLNKRKMIGCIFSIFISI
                     GTIFIPSPSESFRFKLYEKDYSVVAKAILKVYDEKKLSSESVFYIQSDKNELEKIFSK
                     EVIKKMKKLNRNLDVVKISGNRNLVYFFFGAELQSIDGIVIFKNLKHVKPKLDFINRS
                     IQAPRLEYITNNVYYFKGEL"
     gene            826..1752
                     /locus_tag="KRH23_003885"
     CDS             826..1752
                     /locus_tag="KRH23_003885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extended-spectrum class D beta-lactamase CDD-2"
                     /protein_id="HHS5227140.1"
                     /translation="MKRKNNFIWIVILLVVVAMGVYYVGRKHNNTKQKHDKNHINSEL
                     NKSKVENKKEKINMVDYSDCFEGISGGAIFYNTKNKEYNIYNKELIETRRSPCSTFKI
                     VSTLIGLEKGVINSKESVMGYDGTEYPNKNWNKNLSLEEAFKESCVWYYKKLIDKVDA
                     KSVQNILDDLKYGNCDISEWEGDLKNGKGHLNGFWLESSLQISPKEQVQTMAKIFEGD
                     TNFKKEHINILRDIMKIDVNDKNINVYGKTGTGFDEKNKRVDAWFVGMLEREGDTYYF
                     AIKSDDSNKEITGPKVKEIAINIIKKYYSVRE"
     gene            2096..2779
                     /locus_tag="KRH23_003886"
     CDS             2096..2779
                     /locus_tag="KRH23_003886"
                     /EC_number="7.6.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHS5227141.1"
                     /translation="MEILKCENLTKIYGSNQTRVTALNNVNLSVQKGDFVSIVGASGS
                     GKSTLLHLLGGVDRPTSGKIYVEDTEISSLKEEALAVFRRRKVGLIYQFYNLIPTLDV
                     RKNILLPMLLDKRKVDEDRFSEIVSILGLSDRLNHLPSQLSGGQQQRVSIARSLIYRP
                     AILLADEPTGNLDRKNSEEIVDLLNLSNKRFNQTILLITHDEKIALEANRIVTMEDGV
                     IVSEKVVKK"
     gene            2776..5436
                     /locus_tag="KRH23_003887"
     CDS             2776..5436
                     /locus_tag="KRH23_003887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHS5227142.1"
                     /translation="MNILQEYTLDFVRRNKRSSIAIMLAILLTTTMMSSLCGLLYTMW
                     TDFIKLSIEKEGNWHGELFDYTYGSDLPLIENFSSVDDVMVKGQWYVGKINDEKRDYI
                     IYRNATSEYWDSMPEKDTIIEGRRPNNANEIALSKQYFENNPSVKIGDKITLPIGDRI
                     LNGKPLEPIAPKSKGESFKKISEATLTIVGKVDVSTSSVIPAYTALGYLDKTSIKPND
                     SITVYLRFKNIRDTYKELPKLAKSLGWKTNEYGKYNLKYNSNYLLKMLVFSPEQKASM
                     SSISKFSTPIMYLTIAIFTVAVFVMVIYNAFSLSANARLTQLGILSSVGASPKQIKRS
                     VVFEGFLLTIIPLPIGLFLGWLLCNRLIVYVNSVNYHTDVPEVVFTYGIPAFLPAVLL
                     TIVTVWISALIPARKVSKISPIEAIRQGDSVKIKKSHKYSLGKIFGIEGELASNALRA
                     RKKSYRTATISLTLSFLLLTCFLHIIANQEGAKAVYGSDNYKDQRDIEVYLENSEPVE
                     SAFIEKLDNTEGVKSSLYYQKMSASTWLTEKDASKELAKNGGFKNIASSKKYSPIERD
                     GKFRIISNIIGLDDKSFTEYCRQISVDPKLFYDTKNPTSIVYNKEEDINRSTRRNKVY
                     IDYLNLSIGDNIKLNEKVYDEDKGDYTYNMKVGAITSTLPKIVDTSSKYTLMQIVPMS
                     MVQEISKNYDEVSRLRSNRLIGVFKVNNREDIPRVREKLESIYNKDYGSGDYSIEDVL
                     ESEKQKASGIKTMNLIVGFITGLLAMIGLSNVLATVSGNIRSRRQEFAMLRSVGLSPE
                     GIKKMLILEGLFLGITPLLLSIPVQIGIVYAFLRINEIYFIEYLPFAPISTIIGFTIL
                     ILFIVIASYMTGYKQLKNENIVESIKNETI"
     gene            complement(5617..6798)
                     /locus_tag="KRH23_003888"
     CDS             complement(5617..6798)
                     /locus_tag="KRH23_003888"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HHS5227143.1"
                     /translation="MKTPRNINSTVVFIIFCLIVTFLLTVILTTITSFNEYNVLSKAL
                     GASYEYNPKSTESILKSLKNSSDKDFKTGNEILSKHGYSKSTFWSKNFFYFLVISFGI
                     ISTMATVVYIIKHRTNKQKLSRINNLTQYLEEVNLGKESVLLRCEDEFSHLEDEIYKT
                     VGELRCSKEFALKERQTLSDNLADIAHQLKTPITSMSLMAQLLSENCPDEEIDYINRL
                     TNQISRLERLVSSLLTLSKLDASTLIFESKLIDVHSLLTYAIEPIEGSLREKHQTFTI
                     EASPSVEFEIDINWTLEALLNILKNCSEHIEDGGYIVAYYSQNPLYVEIIIEDNGKGF
                     AQEELPYIFNRFYRGKNASKDSIGIGLALSKSIIERQNGTIHAENCHNGGARFIIKFY
                     T"
     gene            complement(6798..7460)
                     /locus_tag="KRH23_003889"
     CDS             complement(6798..7460)
                     /locus_tag="KRH23_003889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HHS5227144.1"
                     /translation="MAKILLLEDDDTITFGIKTSLEKKNHTVCCYNTIAEAKKNFDKT
                     IDLILLDLNLPDGIGYEFCQYVKSIEDTPVIFLTVRDDEKDIIRGLDMGADDYVVKPF
                     LLSVLQSRINAVLRRTHSNTNNTITCENISLNKVEVKAYLDNVEVPLTAGEYKLLLSL
                     MENKNRAMTRTKLLEMLWDVDGNFVNDNTLTVTIKRLREKLKNPPCIKTLRGIGYRME
                     DN"
     gene            complement(7592..8230)
                     /locus_tag="KRH23_003890"
     CDS             complement(7592..8230)
                     /locus_tag="KRH23_003890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HHS5227145.1"
                     /translation="MSELSKRDKEKIQRENEIIDKAEKLFCLNGFDNTTMNELAKEVE
                     YTKRTIYKYFSCKEDLFFAVVLRGYKRLWDNVKIESAKGKTGFEKIKLSYFAFHKFYS
                     VEPSLLCLMGMIGIVNSEKSDTDMLFKEKFFSFNKFMFDEIQGMFEIGKNDRSIRHDI
                     EIPTLMYSSIFTLTGFFNLLSVTGKSYLNNFNIDEEKFIETTLALLIDSIKA"
     gene            8409..8627
                     /locus_tag="KRH23_003891"
     CDS             8409..8627
                     /locus_tag="KRH23_003891"
                     /inference="COORDINATES: protein motif:HMM:NF012955.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HHS5227146.1"
                     /translation="MKIKENVLMLDSTRGSNCFIVFDKEIILIDTGLPFMGKNIIKEL
                     KTLGIKLTDIKHILLTHHDVDHISILNY"
     gene            8624..9013
                     /locus_tag="KRH23_003892"
     CDS             8624..9013
                     /locus_tag="KRH23_003892"
                     /inference="COORDINATES: protein motif:HMM:NF012955.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HHS5227147.1"
                     /translation="MKEKTGAKVWAHVEDIPFIIGEKDRPGFKKFIGKAISRRLIKDV
                     EPYGENMQIGNIKIIHTPGHTPGHVCMIFEDVLFAGDLVKNKNGNIVPYPNPWNWDYK
                     KMIKSIRELDNLKYEWICMSHGTPCIK"
     gene            9114..9836
                     /locus_tag="KRH23_003893"
     CDS             9114..9836
                     /locus_tag="KRH23_003893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HHS5227148.1"
                     /translation="MIRTLILYYLNIKPTHGYEIQKFLQVSGADRWTKIQSGSIYYAL
                     AKLEKDGGVRVLKEEKTGARIRKIYEITQSGKLELREEIQKELQMPIVPTGSNKFLLH
                     NILDVLPKDTLQKNLEKHIKYLIEQKKYWENWKEIKKIDKKSLATEKIAFDMTIDNLN
                     YQILWHEEILNNIDKYISVGCETQNIIKSIDFSNIEEDFLFTSDTTNELLEVQRLRDE
                     IINNPDKAIENIDKIILKLQNK"
     gene            9941..10699
                     /locus_tag="KRH23_003894"
     CDS             9941..10699
                     /locus_tag="KRH23_003894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHS5227149.1"
                     /translation="MSNVLLEIKNLSKKYNNKEVVSRESFKLLEGDILGFIGPNGAGK
                     STSINMLTTIVSPDSGSIYYKGKDIKNQQNIFKSSLGVVPQELAIYEDLSAYDNVKFF
                     CSLYGFKGNELKERIKYALEFVGLWESHKEFPSKFSGGMKRRLNIACAIAHSPQILIM
                     DEPTVGIDPQSRNKILEAIKGINNNGTTVIYTSHYMEEIETLCNRIVLIDKGVIIEDL
                     DKSLYKNKYLKFGCKTLEDIFLYLTGTDLRDLEE"
     gene            10704..11444
                     /locus_tag="KRH23_003895"
     CDS             10704..11444
                     /locus_tag="KRH23_003895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHS5227150.1"
                     /translation="MRCFLTLFKLGIKRRSKDFFILFYNIVFPVIIIVLLGYLTSKSY
                     GKEFTSYNYYTIVTIPFCVLMGIISVSYVAQDEKISNTSYRYMISPVSIVDLVISKLF
                     SCTTVFSIYNLITLVVLRGIFHMSFGGKFLVVIFFLMCESIAVVSMGLFLGLVCKNLD
                     MLRNIINIPIVIFGFLGGVFFPVSSLNPVISLIINISPLTWINRGIVACIYDNNLQLL
                     FNISCIFVAVSIFMTILTIKFFKKEVFI"
     gene            11444..12496
                     /locus_tag="KRH23_003896"
     CDS             11444..12496
                     /locus_tag="KRH23_003896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHS5227151.1"
                     /translation="MNVINVFNSNLKRNINKRIVFLVTLLFPIIIVVLGVLANYISKP
                     SFNIGILDEYKNECILKESEKRTYENTIMALENTQGINTEIADFKTIKTDIITGKYSA
                     VVCFNKNGFELYSIKDKNTNDTLKYLIETYKKDPVPVDISKLQENTLGVLQRIIAFIV
                     LFLMITSTVTASMIIKDKNSGTFTRVLYSPQNIRGYVLGNMLYNFTITYFQYIVSISI
                     IKLFNIDISMDYIDLILMGVWISALATSFGTFVSSLFNKEMHANLFSTCISLILSLIG
                     GSFISVEKMPTMLQKISIISPTQWFISFVTYIEERDGSFFNMNYICILTFIIIILALL
                     AMKFTQRSKYSSNRNY"
     gene            12778..13527
                     /locus_tag="KRH23_003897"
     CDS             12778..13527
                     /locus_tag="KRH23_003897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HHS5227152.1"
                     /translation="MRLESLVNQNYDNLNENDKIIIKQILICQREYRNFSCEKIANEC
                     NVSRATLLRLCRKIGLDSFSDLKYLLKNNQLEFVNNDNNFHDVCENYRLLMNELQKIS
                     FQDICKIIYDAETIYIYGTGNEQKSLAQEIKRIFLSVGKCVIDLFDIGEIEFMRESFQ
                     KSDLFIIISLSGETKAGIEIAKFINNHIHTISLTRLDNNTIATLCEYNLYVETQKLDT
                     LQAISYEVVGAFYALLDLLHMNYIEYRRRKE"
     gene            13524..14288
                     /locus_tag="KRH23_003898"
     CDS             13524..14288
                     /locus_tag="KRH23_003898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HHS5227153.1"
                     /translation="MKIEGLFNKYYNSFTANDKYICECILNHKEDCIKLSIDEFADKY
                     HISTSALSRFAQKLQLPGYSELRVIIRLNETEVEYKNQSKHQLMDCYNKVINDIEKKD
                     CSIMFERMKKANRIIVFGEGYSQERVAKEMKRIFLPTGKIIYDVYGYDMIQALNHFIK
                     TDDMIFFISLNGDASTIIDFAKEMRMKGIYMVSITKMISNPLARLCDENLYIQSISIS
                     VDKQLDYDVTTPYFILIELLYIKYKMYLESEHIPRK"
     gene            14387..15208
                     /locus_tag="KRH23_003899"
     CDS             14387..15208
                     /locus_tag="KRH23_003899"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HHS5227154.1"
                     /translation="MKLYKLLILDIDGTLRDEVYGIPESAKHAIRLCQKNHCSVVICT
                     GRSMGTIQDDVLSLGVDGYIAGGGNYIQYHGELLYNQSFNQRLIKEVVCLLKKREVAF
                     SIESQEKVFMNQKAKEIFETMNQLKGTNSCINKQHIQEKITYENNIEEYKSQDIHKIC
                     LWSNEKVFDEVKDILQDKMELAQRDISSQYYEIIQKDFHKGKAIKRLQERLGVTQKET
                     ICFGDGQNDIVMFQASDVTIAMKNSHQQLKDIATSICEDIFDNGIYKELKRRNII"
     gene            15222..16886
                     /locus_tag="KRH23_003900"
     CDS             15222..16886
                     /locus_tag="KRH23_003900"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_function: GO:0004556 - alpha-amylase activity [Evidence
                     IEA];
                     GO_function: GO:0004574 - oligo-1,6-glucosidase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009311 - oligosaccharide metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 13 protein"
                     /protein_id="HHS5227155.1"
                     /translation="MEKKWWQKEIVYQIYPRSFQDSNNDGIGDLQGIISRLDYLKDLG
                     ITSLWLCPIFKSPMDDNGYDISDYLDIASEFGSMEDLKELIKESKDRGIKIILDLVLN
                     HTSDEHPWFQEALKNPESSYHDYYIFKKGNDLPNNWRSVFGGSVWEKVENRDEYYFHS
                     FGKKQPDLNWENPILRSELYQMINTWSQMGVAGFRVDAITFIKKNLSFQSLESDGVDG
                     LVKCTKTVRNQPGIEKMLYELKENTFKKYDCMTVAEAAGISYDQLGDFIGEDGFFSMV
                     FDFKHADLDVASGSEWFKRISWTIPDLRKCILDSQMYVQEHGWAANFIENHDQPRATT
                     KYLLQYERNDDAVKMLGAMYFFLRGTPFIYQGQELGMTNFKRDNINDFNDLSSIDQYY
                     RSIDEGYSEEEALEFVNLRSRDNARTPFPWADKENAGFSDTTPWLKVIENYKDINAQS
                     QINNSESILEFYKKMIKLRQDSEYSDCLIYGSIEPIDIESDDVIAYRRQLDLVVIDCY
                     YNFSDKPVEIRVEEKYDIVFQNLDDINPLNKTVRLKPFHAILLKAR"
     gene            16891..>18663
                     /locus_tag="KRH23_003901"
     CDS             16891..>18663
                     /locus_tag="KRH23_003901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose PTS transporter subunit IIA"
                     /protein_id="HHS5227156.1"
                     /translation="MNKYNKIANELIKIIGEDNIISITHCATRLRVMVKDREIINDKK
                     VEKVDEVKGVFFTSGQYQIILGTGIVNKVYAEVEKMGLKTLSKKEQDELVKNNETGFK
                     KVMRTLADIFVPIIPVIAATGLFLGLKGCLFNDNVLGLLGMSSANIPLYIQTLVSVLT
                     ETAFAFLPAIIVWSAFKVFGGTPVIGLVIGLMLVSPILPNAYSVADPSNEIEAIMAFG
                     FIPIVGCQGSVLTAIVTAFIGANLEKWFRKHMPNVLDLIFTPFFVMLITMLVILLGVG
                     PIMHTIELKMVDIISLLIDLPLGIGGFIIGFTYPLAVITGLHHTYVMIETSLLANTGF
                     NALITLCAMYGFANIGTCLAFMKKSKNNQVKQTAVGAMLSQLFGISEPVLFGIQLRYN
                     LKPLIIMCASSGLGAAILSILHIQSNSYGLAVLPSYLMYIYDGYNLITYLLVSIFVVA
                     FCFIVTCLFGVPKEAINEDEDEELVFNENNENFVSPAKGKIVALENVPDETFSKKMLG
                     DGFAIDIIDGKIVSPISGKLETVFSSGHAFGIKGTNGEVLIHVGIDTVALNGDGFDVA
                     VKQGDMVKQGDVLVNVDLKRIHELG"
BASE COUNT         7050 a         2080 c         3075 g         6458 t
ORIGIN      
        1 ctattgtaat atttaaatat tacaatagta agttttaaat aaagaataaa taattacctc
       61 acaaactgaa aggaggacat aatgatacta atagttatat tgagtatatt catcatagcc
      121 tcaatcaaca taattatatt aggtaaagaa aatataagag atatagttat ccctttaact
      181 ctatttattg taagtgattt tttatttttg tgtggaaata taatatgtag gggaggagta
      241 atgctactat ttataggttt atttgcaata ccattgatgc taattgcatt tatatggatt
      301 tgtgtacata tgattaagct ttactataaa aaagatttaa ataaaagaaa aatgattgga
      361 tgtatattta gtatctttat aagtataggt actatattta ttcctagtcc aagtgaaagt
      421 tttagattta aactttatga aaaagattat agtgtagtag ctaaagctat tttgaaagtt
      481 tatgatgaaa aaaagttaag ctctgaatct gtcttttata ttcaatctga taaaaatgaa
      541 ttggagaaga tattttctaa agaagtaata aaaaaaatga aaaaactaaa cagaaattta
      601 gatgtagtta aaatttctgg gaatagaaat ttagtctatt ttttctttgg agctgaatta
      661 caatctattg atggtattgt gatttttaaa aatttaaaac atgttaaacc aaagttagat
      721 tttataaata gaagtattca agctcctaga ttggagtata ttacaaataa tgtatattat
      781 tttaaaggtg aactataaac ttatgtagag gagatggtat aaagtatgaa aagaaaaaat
      841 aattttattt ggatagttat tcttctagtt gttgtagcta tgggagtata ttatgtagga
      901 agaaagcata acaacacaaa acaaaaacat gataagaatc atataaactc tgaattaaat
      961 aaatccaaag ttgaaaacaa aaaagaaaaa attaatatgg ttgactatag tgattgtttt
     1021 gaaggtatta gtggaggagc tattttttat aatactaaaa ataaagaata taatatatat
     1081 aacaaagaat taattgaaac aagaaggtca ccatgttcta cttttaaaat agtttcaact
     1141 ttaattggtt tagaaaaagg ggtaataaac tcaaaagaat cagttatggg atatgatggt
     1201 acagagtatc caaataaaaa ttggaataaa aatcttagtt tagaagaggc atttaaggag
     1261 tcttgtgttt ggtactacaa aaaattgata gataaagttg atgctaaatc tgtccaaaat
     1321 attttagatg atttaaagta tgggaattgc gatattagcg aatgggaagg cgatttaaaa
     1381 aatggaaagg gacatttaaa tggattttgg ttagaatctt cattacaaat atctccaaaa
     1441 gaacaagtgc aaacaatggc aaaaatattt gagggagata caaactttaa aaaagagcat
     1501 attaatattt taagagatat tatgaaaata gatgtaaatg ataaaaacat aaatgtatat
     1561 ggaaaaactg gaacaggatt tgatgaaaaa aataaacgtg tggatgcatg gtttgttggt
     1621 atgctagagc gtgaaggtga cacctattat tttgctatta aatcagatga ttccaataaa
     1681 gaaattacag ggccaaaggt aaaggaaatt gcaattaata taattaagaa atattatagt
     1741 gtaagggaat aaacttaatt ttatttgtaa atattattta cctatagtct gtaatattta
     1801 ttaaataatt ttactaaatt gagtctatat agagcaaaac tcctttagta cataaaatac
     1861 ttgctattga ttattaaatt gaatacctat agatttaaag ttaatacctt ttaaagacta
     1921 tgtaatatat taaaagtata aataaaatat attgcatagt ttttgtttta tattataatt
     1981 ttaaataatg tgcaaaaact aaacaatatt tttaatagta atttatattt gtattcatgt
     2041 cactataatg tcattttagg ttgctaaaat ttaaccataa aggagatgat tgtatatgga
     2101 aatattaaaa tgtgaaaatc tcacaaaaat atatggttca aatcaaacca gagtgacagc
     2161 ccttaataat gtaaatttat cagttcaaaa aggtgatttt gtatccattg taggagcatc
     2221 tggttctggc aaatctacat tgttacatct gcttggggga gtagatagac ctacatctgg
     2281 aaagatttat gttgaagata cagaaatatc aagtttaaag gaagaagctc ttgcagtttt
     2341 tagacgtaga aaagtaggtc ttatttatca attttataat cttataccta cccttgatgt
     2401 tagaaaaaat atattattac ccatgttact tgataaaaga aaggtggatg aggatagatt
     2461 ctctgagatt gtatctatat tgggattatc tgatagatta aaccatcttc caagtcaact
     2521 ttcaggtgga caacaacaaa gggtatctat agctagaagt ttaatctata gaccagctat
     2581 tttattagca gatgagccaa ctggtaatct tgatagaaaa aattcagaag aaattgtaga
     2641 cttgttaaac ttatcaaata aacgatttaa tcagacaata cttcttatta ctcatgatga
     2701 gaaaatagca ctagaggcaa atcgtattgt aactatggaa gatggagtga ttgtctctga
     2761 aaaggtggtg aagaaatgaa tattcttcaa gaatacacct tagactttgt acgacgcaat
     2821 aaacgtagta gtatagctat aatgttagct atattactta ctacaaccat gatgtcttct
     2881 ttgtgtggac tgttgtatac catgtggaca gattttataa aactttcaat tgagaaagaa
     2941 ggtaactggc atggtgaatt gtttgactat acttatggaa gtgacttacc attaattgaa
     3001 aatttttctt cagttgatga tgtaatggta aaaggacaat ggtatgtagg caaaattaat
     3061 gatgagaaaa gagattatat aatttataga aatgctacat cagagtattg ggattctatg
     3121 ccagaaaagg atactataat agagggtcgt cgaccaaata atgctaatga aattgcatta
     3181 tcaaaacaat attttgagaa taatccaagt gtaaaaattg gtgataaaat tactctccca
     3241 ataggagata gaatcctaaa tggaaagcct cttgaaccca tagccccaaa atcgaaaggg
     3301 gaaagtttta aaaaaatttc agaggctaca ttgacaatag taggaaaggt agatgtttct
     3361 acttcatcag taatacctgc atatacagct cttggatatc ttgataaaac aagtataaaa
     3421 cctaatgata gtataactgt gtacttgcga tttaaaaata taagagacac gtataaggaa
     3481 cttccaaaac ttgctaaatc attgggatgg aagactaatg aatatggaaa atacaatctt
     3541 aaatacaata gtaattatct tttaaagatg ttagtctttt caccagaaca gaaagcatct
     3601 atgagtagta tatcaaaatt ttcaactcct attatgtatc ttacaatagc aatttttaca
     3661 gtagccgtgt ttgtaatggt gatttacaac gcgttttcac tgtctgcaaa tgctagactt
     3721 actcagttag ggatattatc tagtgttggt gcatcaccaa aacaaattaa aaggtctgta
     3781 gtgtttgaag gctttttact gacaattata ccattaccaa taggtttatt tttaggatgg
     3841 ttattgtgta ataggcttat agtttatgtt aattcagtta attatcatac tgatgttcca
     3901 gaagtggtat ttacttatgg tattcctgct tttctgccag cagttttact tacaatagta
     3961 acagtctgga tttctgcact tataccagca cgaaaagtat caaagatatc tcctatagaa
     4021 gcaatacgac aaggagatag tgttaaaatc aaaaagtcgc ataaatattc attaggaaag
     4081 atatttggaa tagaaggaga acttgcatca aacgcactac gtgctcgtaa aaaatcttat
     4141 cgtactgcaa caatatcttt aacattatct tttttattac ttacatgttt tttgcatata
     4201 attgcaaatc aagaaggagc aaaagctgtt tatggaagtg ataattataa ggaccaaaga
     4261 gatatagaag tttatttgga aaatagtgaa cctgtagagt ctgctttcat tgaaaaatta
     4321 gataatacag aaggtgtaaa aagttcacta tattatcaaa aaatgtctgc ttccacttgg
     4381 ttgactgaaa aagatgcttc aaaagaactt gcgaaaaatg gaggatttaa aaatatagct
     4441 tcatctaaaa agtactctcc tatagaacgt gatggcaagt ttcgtataat ttcaaatata
     4501 attgggcttg atgataagag ttttacagaa tattgtaggc aaatttctgt agacccaaag
     4561 ttattttatg atacaaaaaa tccaacctca attgtatata ataaggagga agatattaat
     4621 cgtagtacac gtagaaataa agtatatata gattatttaa atctttcaat aggagataac
     4681 attaaattaa atgaaaaagt atatgacgaa gataaagggg attatactta caacatgaaa
     4741 gtgggagcta ttacaagcac acttcctaaa atagtagata ctagttcaaa gtatacatta
     4801 atgcaaatag ttccaatgtc tatggtgcag gaaatatcta aaaattatga tgaagtaagt
     4861 aggttacgtt caaataggct gataggagta tttaaagtaa ataatcgtga ggacattcct
     4921 agagtaagag aaaaattaga gtccatttat aataaagact atggttcagg agattatagt
     4981 attgaggatg ttttagaaag tgaaaaacaa aaggctagtg gaataaagac catgaattta
     5041 atagtaggct ttattacagg tttattggct atgattggat tatcaaatgt acttgctaca
     5101 gtgtcaggaa atattagaag tagacgacaa gagtttgcta tgttgcgttc tgttggatta
     5161 tctccagaag gcataaaaaa gatgcttatt ttggaaggtt tattcttagg aattacacca
     5221 ttactactta gtattcctgt gcaaatagga atagtgtatg cttttctacg tataaatgaa
     5281 atatatttta tagagtattt accatttgca cctatatcta caataatagg ttttactata
     5341 ttgatacttt ttattgtaat agcatcatat atgacaggat acaagcagtt gaagaatgaa
     5401 aatatagtag aatctataaa aaatgaaaca atataaacaa aatctatttg aacttattta
     5461 aaggtttcga tttaagacta cttacaagta tagggatagt taagttgttt gtttaataaa
     5521 accttaaatg taaatagaag tatattacta aaacaataga taacatagaa tatagatata
     5581 gctggattat aggtatttta cctataatcc agcattttat gtgtaaaatt taattatgaa
     5641 tcttgcacca ccattatggc aattttctgc atgtatagta ccattttgac gttctataat
     5701 agactttgat agagcaagcc ctataccaat actgtcctta ctagcatttt taccacgata
     5761 aaatctatta aaaatatatg gaagttcttc ctgagcaaac cccttaccat tatcttctat
     5821 gataatctca acatatagag gattttgact ataataagca actatatatc caccatcttc
     5881 tatatgctca ctacaatttt taagaatatt taaaagagct tctaaagtcc aattaatatc
     5941 gatttcaaat tctaccgaag gagaagcctc gatagtaaat gtctgatgtt tttctcttaa
     6001 agaaccttct ataggctcaa ttgcataagt aagaagagaa tgtacatcta taagtttgct
     6061 ttcaaatatt aaagtacttg catccaattt tgataatgta agtaaagatg aaactagtct
     6121 ctcaagtctt gagatttgat ttgtaagtct gttaatataa tctatttctt catctggaca
     6181 attttctgaa agtaattgtg ccataagtga catagaggta attggagtct taagttgatg
     6241 agcaatatct gcaagattat ctgaaagagt ttgtctttct tttaaagcaa attcttttga
     6301 acaacgaagt tccccaactg ttttatatat ctcatcttca aggtgagaaa attcatcttc
     6361 acatcgtaaa agtacagact cttttcctaa attcacttct tctaagtatt gagtaagatt
     6421 gtttattcta ctcagttttt gcttatttgt tctatgtttg attatatata caactgtagc
     6481 cattgttgaa attataccaa acgatatcac tagaaaataa aaaaagtttt tactccaaaa
     6541 tgtactttta gaatatccat gttttgataa aatttcattt cctgttttaa aatccttatc
     6601 actagaattt ttcagtgatt ttagtatact ttctgtagac ttaggattgt actcatatga
     6661 tgcaccaaga gccttagaca gtacattgta ttcattaaaa gaagttatag ttgttagaat
     6721 tacagtcaat aaaaaagtta caattaagca gaatattata aaaacaactg tactgttgat
     6781 atttcttgga gttttcacta gttgtcctcc attctatatc ctatgcctct taatgttttt
     6841 atacaaggtg gattttttaa tttttctcta agacgtttta ttgtaacagt aagagtgtta
     6901 tcatttacga aattaccatc tacatcccag agcatttcta gtaactttgt acgagtcata
     6961 gctctatttt tattttccat aagacttaga agaagtttat attctcctgc tgtcaaaggt
     7021 acttcaacat tatctaaata tgctttgact tcaaccttat tcaagcttat attttcacat
     7081 gtaatagtat tgttagtatt tgaatgagtt cttctaagaa ctgcattaat tctggattga
     7141 agtactgaga gcaaaaacgg tttaaccaca tagtcatctg cacccatatc taatccacgt
     7201 ataatgtctt tttcatcatc acggactgtc aaaaatatta ctggagtatc ttctatactt
     7261 ttaacatatt ggcaaaactc gtatccaata ccatcaggta gatttaaatc aagcagaatt
     7321 aaatcaatag ttttatcaaa atttttttta gcttcagcaa tcgtattata acaacataca
     7381 gtgtgatttt tcttttcaag ggaagttttt attccaaatg taattgtatc atcatcttct
     7441 aaaagaagta ttttagccat ttacttttaa tcctttcagt aatttagtta ttccattaac
     7501 taagttatta gttttatgtt taatattttt tatattagag atagaaaaaa ttatcattta
     7561 agtatataaa ctttaattta taaacttagg tttatgcttt aattgaatct attaaaagag
     7621 caagagttgt ttcaataaat ttttcctcat ctatattaaa gttgttcagg tatgattttc
     7681 ctgttacaga tagtaaatta aaaaatcctg taagtgtaaa tattgatgaa tacataagag
     7741 taggtatttc aatatcatgc ctaatacttc tatcattttt tccaatttca aacattcctt
     7801 gtatttcatc aaacataaat ttattaaaag aaaaaaactt ttctttaaac agcatatcag
     7861 tatccgattt ttcagagttt acaataccaa tcattcccat aaggcataat agagaaggtt
     7921 ctacagagta aaatttatga aaagcaaagt atgaaagttt tattttttca aaccctgttt
     7981 tgccttttgc actttctatt ttaacattat cccaaagtct tttatatcct cttaagacaa
     8041 cagcaaagaa taaatcttct ttacatgaaa agtacttgta tatggtgcgt ttagtatatt
     8101 caacttcttt tgctaattca ttcatagttg tattatcaaa tccattaaga caaaataatt
     8161 tttctgcctt atcaataatc tcattttctc tttgtatttt ttctttatct ctttttgata
     8221 attctgacat ataaattatt cctttctatt gataaaaaag tatactgatg gtatacttat
     8281 gtaaatataa tacttgtata cctatagtat actttaataa aaaataaaat taatatcaag
     8341 tattataact atttataact ttattaatta attatatagg taaaatacca aataagggga
     8401 atttatttat gaagataaaa gaaaatgtat taatgttaga tagtactcgt ggctcaaatt
     8461 gttttattgt gtttgataaa gaaattattc ttatagacac aggtcttcct tttatgggga
     8521 aaaatataat taaagaatta aaaacacttg gcattaaact tacagatatt aagcatattt
     8581 tattaactca tcatgatgtt gaccatatat ctatattaaa ttattgaaag aaaaaacagg
     8641 agcaaaagta tgggctcatg tagaggatat accttttatt ataggagaga aggatagacc
     8701 tggatttaag aagtttattg gaaaggcaat ttccagaagg ctcattaagg atgttgaacc
     8761 ttatggagag aatatgcaga ttgggaatat aaaaattatc catactcctg gtcatactcc
     8821 agggcatgtc tgcatgattt ttgaagatgt attatttgca ggtgatttag tcaaaaataa
     8881 gaatggaaat atagttcctt atcctaatcc atggaattgg gattataaaa agatgataaa
     8941 atctataaga gaattggata atttaaaata tgaatggata tgtatgtctc atggaactcc
     9001 ttgtattaaa taataaaaat aataagttgt aatatatcct atgttatcta ttgactatat
     9061 ccaatgttgg tgataatata atatccaaga tagagtatag gtggtgaatt tttatgatac
     9121 gcactttaat tttatattat ctaaatatta agccaacaca tgggtatgag attcaaaagt
     9181 ttttacaagt atctggtgca gatagatgga ctaaaataca atctgggtca atatattatg
     9241 cattggcaaa attagaaaag gatggaggag ttagagtttt aaaagaagaa aaaacaggag
     9301 ctaggattcg taaaatctat gagattactc aaagcggtaa attagaatta agggaagaaa
     9361 tacaaaaaga gcttcagatg ccaatagttc caactggttc aaataaattc ctattacata
     9421 atattttgga tgtattacct aaggatactt tgcaaaaaaa tcttgaaaaa catataaaat
     9481 atcttataga gcagaagaag tattgggaaa attggaaaga gattaaaaaa attgataaaa
     9541 agagtcttgc aacagaaaaa attgcatttg atatgactat agataatctg aattatcaaa
     9601 ttttgtggca tgaagaaata ttaaataata tcgataagta tatatctgtt ggttgcgaga
     9661 cacagaatat aattaaatct atagactttt caaatataga agaagatttt ttatttacat
     9721 ctgatacgac aaatgagtta ttagaagttc aaagacttag agatgaaata attaataatc
     9781 cagataaagc tatagaaaat atagataaga taatactgaa attacaaaat aagtaataaa
     9841 ttttattata ataacacgag taaaacactc gtgttttaaa aaaactatat atacaatatt
     9901 ggatatataa tgttggttaa atattaggag gattttataa atgagtaatg tattgttaga
     9961 gattaaaaat ttatctaaga agtataacaa taaggaagtt gtatcaagag aaagttttaa
    10021 gttattggaa ggagatattt taggttttat tggaccaaat ggagcaggga aaagcacatc
    10081 tatcaatatg cttactacga ttgtgtctcc agacagtgga agcatatact ataaaggaaa
    10141 agatattaag aatcaacaaa atatttttaa aagctcactt ggagttgtac cacaagaatt
    10201 agcaatatat gaagatttaa gtgcatatga taatgttaaa tttttttgct cattatatgg
    10261 atttaaaggg aatgaactta aagagagaat taaatatgcc ttggaatttg ttggcctttg
    10321 ggaaagccat aaggagtttc catcaaaatt ttctggtgga atgaaacgta gactaaacat
    10381 agcttgtgca attgcacata gtccacaaat tctcatcatg gatgagccaa cagtaggtat
    10441 agaccctcaa tcaagaaata aaattttgga agcaattaaa ggcattaata ataatggcac
    10501 aacagtcata tatactagcc actatatgga ggaaattgaa actttatgta atagaattgt
    10561 tttaatagat aaaggagtaa ttatagaaga tttagacaag agtttatata aaaataaata
    10621 tttaaaattt ggttgtaaga cattagaaga tatttttcta tatcttacag gtacagattt
    10681 gagagatttg gaggaataaa tagatgagat gttttttaac attgtttaaa ttaggaataa
    10741 aacgaagaag taaagatttt tttattctgt tttacaatat tgtttttcca gtaataatca
    10801 tagtattatt aggctatttg acatcaaagt cttatggtaa ggaatttaca tcatataatt
    10861 attatactat tgttacaata ccattttgtg ttcttatggg aattattagt gtttcatatg
    10921 tagcacaaga tgaaaaaatt tctaacacat catatcgtta tatgatttct cctgtttcaa
    10981 tagtagattt agttatttca aaactttttt cttgcacaac agtattttcg atatacaatt
    11041 tgataacttt agtggtgtta agaggaattt ttcatatgag ttttggtggg aaatttttag
    11101 ttgttatttt ctttttaatg tgtgaatcta ttgcagtagt atctatgggg ttgtttttgg
    11161 gtcttgtttg taaaaattta gatatgttac gtaatatcat taatataccg atagttattt
    11221 ttggcttctt aggaggagtg ttctttccag ttagttcatt gaatccagtt atttcattaa
    11281 tcattaatat atcaccatta acatggatta atagaggcat agttgcttgt atctatgata
    11341 ataatttaca actccttttt aatatatcat gcatatttgt agctgtaagc atatttatga
    11401 caatacttac aatcaaattt tttaaaaagg aggtctttat atagtgaatg taataaatgt
    11461 ttttaatagt aacttaaaaa gaaatataaa taagagaata gtgtttttag ttacactttt
    11521 atttcctata attatagtag ttttaggagt attggcaaat tacataagta aaccatcttt
    11581 taatattggt attttagatg agtacaaaaa cgaatgcatt ctaaaggaat ctgaaaaaag
    11641 aacctatgaa aatacaataa tggctttaga aaatactcaa gggattaata cagagattgc
    11701 agattttaaa acaattaaaa ctgatattat aacaggcaag tattcagctg tcgtatgttt
    11761 taataagaat ggttttgagt tatattctat aaaagataaa aatacgaatg atacattaaa
    11821 gtatttaata gaaacatata aaaaagaccc agttcctgta gatataagta aattacaaga
    11881 aaatacttta ggagttttac aaagaataat tgcatttatc gtattatttt taatgataac
    11941 atctactgta acagcatcaa tgattattaa agataaaaac tcaggtacat ttacaagagt
    12001 gctatattct ccacaaaata taagaggata tgtgctaggt aatatgttat acaactttac
    12061 aataacgtat tttcagtaca tagtttcaat atctataatt aagttattta atattgatat
    12121 tagtatggat tatatagatt taattttaat gggagtatgg atatcagctt tggcaacttc
    12181 ttttggaaca tttgtatctt ctttattcaa taaagaaatg catgcaaatt tgttttctac
    12241 atgtatatca cttatattat cacttattgg tggttcattt atttcagttg aaaaaatgcc
    12301 aacaatgtta caaaaaatta gtattataag cccaacacaa tggtttatta gttttgtgac
    12361 ttatatagaa gaaagagatg gaagcttttt taatatgaat tatatttgta ttttgacatt
    12421 tataataata attttagctt tgttagctat gaaatttact caaagaagta aatattcaag
    12481 taataggaat tattaaataa gatagaaaat gaatagatgt aattaaaaca aatcaggaga
    12541 taaaaatata aatatggttc tatatattat aaattgggtt taattataaa aatagaaatt
    12601 atatagtgta aaaaataatg tgaaaaattt tttatttata atagaactgt ggtatgagca
    12661 aattaaattt gttctgagat agctcttttt tatttgtctt aatagaaata tttttaagac
    12721 tcttccctag aaaaagcaac taatgtatat taaaataata tttagggagt ggaaaaaatg
    12781 agattagaat cgttagttaa ccaaaattat gataatttaa atgaaaatga taaaattatt
    12841 attaaacaaa tattgatttg tcaaagagaa taccgtaatt tttcgtgtga aaaaattgca
    12901 aatgaatgta atgtttctag agctacttta ttaaggcttt gtagaaaaat tggattagat
    12961 tcattctctg atttaaagta tttacttaaa aataatcaac tagaatttgt taataatgat
    13021 aataattttc atgatgtttg cgagaattat cgactattaa tgaatgaatt acaaaaaata
    13081 tcatttcaag atatttgtaa aataatatat gatgcagaaa caatttatat ttatgggaca
    13141 ggtaatgaac agaaaagttt agctcaagaa ataaagagaa tatttctttc agtaggtaaa
    13201 tgtgttattg acttatttga tataggtgaa attgaattta tgagagaatc atttcaaaaa
    13261 agtgatttat ttattatcat ttctttgtct ggagaaacaa aagcaggaat tgaaattgca
    13321 aaatttatca acaatcatat acatacgatt tctttaacta ggcttgataa taatacaatt
    13381 gcaacacttt gtgagtataa tctgtatgtt gaaacgcaaa aacttgatac attacaagct
    13441 atatcttatg aagtcgtagg agcattttat gctctattag atttgcttca tatgaattac
    13501 atagagtata gaaggagaaa agaatgaaaa ttgaaggact tttcaataaa tattataatt
    13561 catttacagc aaatgataag tatatctgtg agtgtattct taatcataaa gaagattgta
    13621 ttaaactttc tatagatgaa tttgcagaca aataccatat atctacaagt gcactttctc
    13681 gttttgctca aaaactacaa ttacctggat atagtgaatt aagagttatt atacgcttaa
    13741 atgaaacaga agtagaatat aaaaatcaaa gtaaacacca attaatggat tgttataata
    13801 aggtgataaa tgatatagag aagaaggatt gttcgattat gtttgaaaga atgaaaaagg
    13861 caaatcgtat aatcgtcttt ggagaaggtt attctcagga aagagttgct aaagagatga
    13921 aaaggatttt cttaccaaca gggaaaatta tatatgatgt ttatggttat gatatgattc
    13981 aggcacttaa tcattttata aaaacagatg atatgatttt ctttatttca ttgaatggag
    14041 atgcatctac aattattgat tttgctaaag aaatgagaat gaaaggaatt tatatggttt
    14101 ctattacaaa aatgataagt aatcctttag caagattatg tgatgaaaac ctgtatattc
    14161 aatctatatc tatttctgta gataaacaac tggactacga tgtaacaaca ccttatttta
    14221 ttttaattga actgctttat attaaataca agatgtattt agaaagtgaa catattcccc
    14281 gaaaatgaaa atttgtgcta aaaatgaaca tattttttaa aagatatcaa aatattgata
    14341 tctttttttt tgaatgctat tatgattttg atagtaagaa aggaagatga aattgtacaa
    14401 attattaata cttgatatag atggtacgct tagagatgag gtatatggaa tcccagaatc
    14461 tgcaaagcat gctatacgtt tatgtcaaaa gaatcattgc agtgttgtta tttgtactgg
    14521 aagaagtatg ggtacaatac aagatgatgt tttatcatta ggagttgatg gatatattgc
    14581 aggaggaggt aattacattc aatatcatgg tgaattactt tataatcaat cttttaatca
    14641 aagattgata aaggaagttg tttgtttatt aaaaaagaga gaagttgctt tttcgattga
    14701 gagtcaggaa aaagttttca tgaatcaaaa agccaaagaa atatttgaaa caatgaatca
    14761 gttgaaagga actaattctt gtataaataa acaacatatc caagaaaaaa taacatatga
    14821 aaataacatt gaagagtata agtcacaaga tatacataaa atttgtttat ggtcaaatga
    14881 aaaggtattt gacgaagtga aagatatact acaagataaa atggaattag cacagagaga
    14941 tatttctagt cagtattatg aaattattca aaaagatttt cataagggca aagcaattaa
    15001 gagattacaa gaaagattag gagtaactca aaaagaaacc atatgttttg gtgatggtca
    15061 aaatgacatt gtcatgtttc aagcatcaga cgttacaatt gcaatgaaaa atagtcatca
    15121 acaacttaaa gatatagcga catctatatg tgaggacata ttcgataatg gaatttataa
    15181 agaattaaaa agaagaaata tcatataaaa aggagtaatt tatggaaaag aaatggtggc
    15241 aaaaagaaat cgtttatcaa atttatccaa gaagctttca agatagtaat aatgatggaa
    15301 ttggagattt acagggaatt atttctcgtt tagattattt aaaagattta ggtattacat
    15361 cattgtggtt atgtccaatt tttaaatcac ctatggacga taatgggtat gatattagtg
    15421 attatttgga tattgcaagt gaatttggaa gtatggaaga tttaaaagag ttaattaaag
    15481 aaagtaaaga tagaggaatc aagattatat tagatttagt tcttaatcat acaagtgatg
    15541 aacatccttg gtttcaagaa gcattaaaaa atccagaaag ttcttatcat gattattata
    15601 tttttaaaaa aggaaacgat ttaccaaata actggaggtc tgtttttggt ggaagtgttt
    15661 gggaaaaggt agagaataga gacgaatatt attttcattc ttttggtaaa aaacaacctg
    15721 accttaattg ggaaaatcca atattaagaa gtgaacttta ccaaatgatt aatacctggt
    15781 ctcaaatggg agtggcagga tttagagttg atgctattac attcatcaaa aagaatttaa
    15841 gttttcaaag tttagaaagt gatggtgttg atggtcttgt taaatgtaca aaaacagtta
    15901 gaaatcagcc tggaatagaa aaaatgcttt atgaattaaa agaaaatacg tttaaaaaat
    15961 atgattgtat gactgttgct gaagcagcag gtattagcta tgaccagcta ggtgatttta
    16021 ttggagaaga tggtttcttt tcaatggtct ttgactttaa acatgctgac ttagatgttg
    16081 cttctggtag tgagtggttt aaaagaattt catggacaat tccagattta agaaaatgca
    16141 ttttagatag tcaaatgtat gttcaggaac atggatgggc agctaatttt attgaaaatc
    16201 atgaccaacc aagagctaca acaaagtatc ttttgcaata cgaaaggaat gatgatgcag
    16261 taaaaatgtt gggagcaatg tatttctttt taagaggaac accatttatt tatcagggac
    16321 aggaattagg aatgacaaat tttaaaagag ataacataaa tgattttaat gatttatcaa
    16381 gcattgacca atactatcgt tcaatagatg aaggttactc agaagaagaa gcgttagaat
    16441 ttgtgaattt aagaagccga gataatgcaa gaacgccatt tccatgggca gataaagaaa
    16501 atgcaggttt ttcagataca acaccatggt taaaggttat tgaaaattat aaagatatta
    16561 atgcacagag tcagattaac aattcagaga gtattttaga attttataaa aagatgataa
    16621 agttgagaca agatagtgag tattctgatt gtttgattta tggttcaata gaacctattg
    16681 atatagaaag tgatgatgtt attgcgtata gaaggcaatt agatttggta gttattgatt
    16741 gttattataa tttttctgat aaacctgtag aaataagagt agaagaaaaa tatgatattg
    16801 tattccaaaa tttagatgat ataaatccat taaataaaac agtgcgtttg aaaccatttc
    16861 atgcaatatt attgaaagcg aggtagaaaa atgaataaat ataataaaat agcaaatgag
    16921 cttattaaaa ttattggtga agataatatt atttctatta cacattgtgc cacaagatta
    16981 agagtgatgg ttaaagatag agaaattatt aatgataaga aagttgaaaa agttgatgag
    17041 gttaaagggg ttttctttac ttctggacag tatcaaatta ttttaggaac aggaatagtt
    17101 aataaagttt atgcagaagt tgaaaaaatg ggattaaaaa ctttatcaaa aaaagaacaa
    17161 gatgaattag ttaaaaataa tgaaactgga tttaagaaag ttatgagaac tctagcagat
    17221 atatttgttc ctattattcc agttattgca gcaacaggat tattcttggg attaaagggt
    17281 tgtttgttta atgataatgt acttggatta ttaggaatgt cttctgcaaa tattccattg
    17341 tatattcaga cacttgtttc agttcttaca gaaacagcat ttgctttttt accagcaatt
    17401 attgtatggt cagcatttaa agtatttgga ggaacacctg ttattggact tgttattgga
    17461 cttatgttag tttccccaat acttcctaat gcatattctg ttgctgaccc atcaaatgaa
    17521 attgaagcaa ttatggcatt tggatttatt cctattgtag gttgtcaagg aagtgtttta
    17581 acagctattg ttacagcatt tattggagct aatcttgaaa aatggttccg taaacatatg
    17641 cctaatgtat tagaccttat tttcacacca ttttttgtta tgctaataac aatgttagtt
    17701 attttgttag gtgtaggccc tataatgcat acaatagaat taaaaatggt tgatatcatc
    17761 agcttattga ttgatttgcc tttaggaatt ggaggattta ttattggatt tacatatcca
    17821 ttagctgtta ttactggctt acatcatact tatgtaatga ttgaaacatc actattagca
    17881 aatacaggat ttaatgccct tattactctt tgtgcaatgt atggatttgc gaatattgga
    17941 acatgtctag catttatgaa aaaatctaaa aataatcaag ttaaacaaac tgcggttgga
    18001 gcaatgctat ctcaactttt tggtataagt gagcctgttt tatttgggat tcagcttcga
    18061 tataatttaa agcctttgat tattatgtgt gcatcttcag gtttaggagc agcaatatta
    18121 tcaattttac atattcaatc taattcatat ggattagcag ttttaccttc ttatttaatg
    18181 tatatctatg atggatataa tttaatcaca tacttattag tatcaatatt tgtggttgca
    18241 ttctgcttta ttgtaacatg tttatttgga gtgcctaaag aagctataaa tgaagatgaa
    18301 gacgaagaat tagtgtttaa tgaaaataat gaaaactttg tgtctccagc taaggggaaa
    18361 attgttgcat tagaaaatgt accagatgaa acattttcta aaaaaatgtt aggtgatggt
    18421 tttgctattg atattataga tggaaaaatt gtttctccta tttcaggtaa attagaaaca
    18481 gtattttcaa gtggacatgc atttgggatt aaaggaacta atggagaagt attaattcat
    18541 gttggaattg atacagttgc actaaatgga gatggctttg atgttgctgt taaacaagga
    18601 gatatggtta aacagggaga tgttcttgtt aatgttgatt taaagagaat acatgaatta
    18661 gga
//
LOCUS       DAEORM030000185        17199 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.guided.071, whole genome shotgun sequence.
ACCESSION   DAEORM030000185 DAEORM030000000
VERSION     DAEORM030000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 17199)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17199)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 17199)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17199
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.guided.071"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            <1..612
                     /locus_tag="KRH23_003902"
     CDS             <1..612
                     /locus_tag="KRH23_003902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HHS5227157.1"
                     /translation="KKTYLLVVSMLIAGLLTACSGSPTKDSGQAQDNTKKEANASNNA
                     LKDEKNNENLMEQDFKVPYTDAINIFKDKYKDADIVDLSLERDLNKFVYTVEGVDDNN
                     EYKMKIDANTKDVLEDKTEKLDSEDLNGVARKEKLDLNDIIKPQQAMEIALKEQNGMV
                     KEWSLDKDLDVTFYKIRIDKDKNEYDIKVDSKKGTVLKVEKED"
     gene            720..3251
                     /locus_tag="KRH23_003903"
     CDS             720..3251
                     /locus_tag="KRH23_003903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FprA family A-type flavoprotein"
                     /protein_id="HHS5227158.1"
                     /translation="MSLKSLKIKENLYWVGSLDPDLRVFDIIMYTPYGTTYNSYVLKG
                     TEKTVLFETVKDKHFDNYIERLNDLNIDFEKIDYIVVSHTEPDHAGSVEKLLDLAKNA
                     KVVASETAIKYLKEIVNKDFEYVAVTDGDTLSIGDKTLEFFSVPMLHWPDTIYTYIKE
                     DKTLVTCDSFGSHYSNDKIVNTLDENEEKDYLDALRYYYDCIMGPFKPSMVTAIEKIK
                     DLDIDTVCPGHGPVLTENPRKIIDLYYNWSVNEQIKLEKEVTICYVSAHGYTKIMAEA
                     IKAYIEKNSNYKVNLFDVIEHKQEDILAKIAVSQGVLFGTPTILGDALKPIWDILISL
                     NPVLHGGKVASVFGSYGWSGEGIENAMERISQLRMTAVKPFAVNFKPSNEEIDKLHSY
                     TGKFLDKLNSTFGSKKKTKKFKCVICNEVFEGDSAPSVCPVCGAKEDQFIEVEEDEVT
                     FRKDTDEYFVIVGNGAAGFYAADAIRKRNKTCKITMISNEDELTYYRPALSDGINEEL
                     GSDFYMEDKDWYDKNNIVVILGTNVDKLDEVNKTIIVNDGAIKFDKLVIATGSRNFIP
                     PIKGHDLENVFTLRNIKDLYSVKEALEKSKKVVVIGGGLLGLEAAWEFRLKGLEVVVV
                     EAMDSILSKQLDKEGSKILEQCVRDTGIDVRLGVAVDGIEGDGKAQKVVFKDGDSVDC
                     DMVVFSIGVRANTQMVQDTSVKIDRGIVVDKTLQTNIKDIYACGDVAQVGNISLAIWP
                     SSVEMGKIAGANASGDNLTFESEVYPVSLDAMNVKVFSIGNIQNFDKEISSKDEGQRI
                     YKKLFMKDGSLVGAILINDLSCTVKLIRLISEKGDFEDIMKADIL"
     gene            3685..4386
                     /locus_tag="KRH23_003904"
     CDS             3685..4386
                     /locus_tag="KRH23_003904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin resistance response regulator
                     transcription factor VanR-G-Cd"
                     /protein_id="HHS5227159.1"
                     /translation="MNENILIVDDEKEIADLIEVYLKNEGFTVYKFYTGKEALECIES
                     KNLDMAILDIMLPDIDGFHICQKIREKYYYPIIMLTAKIEDIDKIMGLTIGADDYITK
                     PFNPLEVVARVKTQLRRYMRYNNSYEQQSIIVNEYDIKGLIINKETHKCSLFGKEVAL
                     TPIEFSILWYLCEHQGKVVPSEELFEAVWGEKYLDNNNTVMAHIGRLREKIHEPSKNP
                     KFIKTVWGVGYTIEK"
     gene            4436..5518
                     /gene="vanS"
                     /locus_tag="KRH23_003905"
     CDS             4436..5518
                     /gene="vanS"
                     /locus_tag="KRH23_003905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin resistance histidine kinase VanS"
                     /protein_id="HHS5227160.1"
                     /translation="MRTALMAFIAIIFIWILYSFILYGKFSIWIVSFFENAFRMEYKA
                     ALNLYQQIFRNSMELFMILAMVIVFFIIFRVYLNWFTKYFSEINQGIDSLIKEDVGEV
                     ALSPELLAIEKKINSIKHILEQRKFETQMAEQRKNELIVYLAHDLKTPLTSVIGYLTL
                     LRDESQISEELRKKYLSISLDKAERLEDLINEFFEITRFNLSNISLEYSTVSLTRMLE
                     QLTYEFKPTLMSKNLKYTLNVTPNMMIRCDVNKMQRVFDNLLRNAVYYSFEDTTIEIT
                     AVQEDDYIKLKFINYSNTIPEEKLERIFEQFYRLDTSRNSNSGRAGLGLAIAKEIVEL
                     HNGTITAHSENNIITFKVIIPIVGNL"
     gene            5779..6879
                     /gene="vanG"
                     /locus_tag="KRH23_003906"
     CDS             5779..6879
                     /gene="vanG"
                     /locus_tag="KRH23_003906"
                     /EC_number="6.3.2.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-serine ligase VanG"
                     /protein_id="HHS5227161.1"
                     /translation="MNNKKIAVIFGGNSTEYDVSLQSAFAVLENLNTEKYDIIPIGIT
                     REGNWYHYIGDYNNIQNNTWFERDTDIIPVIVSQNRVKNGIIEFLIPDAVSQNHIPNS
                     AIESCENDIKYTKLDFVFPVLHGKNGEDGTVQGLFELAGIQVIGCGTLSSALCMDKDK
                     SHKLVHSEGIKVPKSILLKYSDKFNVAELSKDLTYPLFIKPVRAGSSFGISKIYKKEE
                     LQVAVDLAFEHDNEVIIEENIDGFEVGCAVLGNNDLLVGRVDEIELSKGFFDYTEKYT
                     LKSSKIHMPARIDLDCEKRIQETAKIIYRTLGCSGFARVDMFLTPSGEIIFNEVNTIP
                     GFTSHSRYPNMMKGIGLSFEEILDKIIEVYIK"
     gene            6876..7682
                     /locus_tag="KRH23_003907"
     CDS             6876..7682
                     /locus_tag="KRH23_003907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HHS5227162.1"
                     /translation="MMNNILLDKNKEDKMTNTILLTKDKVYDGNLILVNAFLPVKTSE
                     DIDLIPVDTRFPSILMKREATNILQNILKSICGINEIVPVSGYRTAEEQQDIYSSSLR
                     DNGKDFTKKFVALPNHSEHQTGLAIDLGLKKEVIDFICPEFPYNGICNEFRKAALHYG
                     FIERYQCKKEEITGISQEPWHFRYVGYPHSEIINKMNLALEEYIEYIKRFSYTNCLKI
                     EDKEKIIEIFYVPIHTKEEVRISIPEQCVYQISGNNKDGFIVTFWRNRKD"
     gene            7700..9838
                     /gene="vanT"
                     /locus_tag="KRH23_003908"
     CDS             7700..9838
                     /gene="vanT"
                     /locus_tag="KRH23_003908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine racemase VanT catalytic subunit"
                     /protein_id="HHS5227163.1"
                     /translation="MIRNKSYAGLDYFRIIAALLIIAIHTSPLLSYSKMADFVLTSII
                     ARIAVPFFFMLSGFFLISTYNYNCNKLKSFLKNVLFIYGIAIVIYIPLNIYTGYFSMN
                     NLVPNIIKDIVFDGTLYHLWYLPASIIGASIAYFLVKKLGLKYSLVITIVIYVIGMFG
                     DSYYGFLEKIPLLKNLYGYIFEVSDYTRNGIFFAPVFFILGGIISNKSNYMSTKNSLI
                     GFLISFLLMLCEGMFLHKLGVQRHDSMYIMLLPCMYFLFTALTFLKGSRARLLRTSSL
                     IIYIIHPMMIVVIRMFSKIFGIQTVLVDNSLIHYIVVSIASFIASIIIILILKPLKKY
                     LKGEHKVNTNRAWIEIDLNNLEHNVKMIQKAMPEDCELMAVVKANAYGHSAFEVATCA
                     NQIGVKAFAVATIDEGIDLRRYGILGEILILGYTNPIRAKELHKYNLTQSVIDLNHAI
                     SLNKQKYNIKSHIKIDTGMHRLGFDVNDVRSILKAFKLKYLDICGIFTHLCVSDSLKD
                     EDVDFTNKQIECFYKLIDFLLKKGIKIHKVHIQSSYGFFNYPNLKCNYVRIGIALYGI
                     LSSPNDTTKLQLDLRPVLSLKSQVILIRKIQKDDSFGYGRVFIASRDSVIAILSIGYA
                     DGIPRNLSCGKSYVIINDCRAAIVGRICMDQLAVDITDIPNVEVGNTAIIIGRDNLAE
                     LSASEVANNSCSISNELLSRVGRRLNVIKK"
     gene            10152..10772
                     /locus_tag="KRH23_003909"
     CDS             10152..10772
                     /locus_tag="KRH23_003909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HHS5227164.1"
                     /translation="MQYIQELLDLTQNYWVLATIIGLLSAFIESFIPALPLVAIVTAN
                     AAIQGLFIGCLLSWIGSGLGTTSLFLLISRFNDSKLFNKLRNSKTEKAISWMDKQGFK
                     LLFIAYACPFMPGCLVTIASAFGKKDLKDFVPAMLAGKFVMFIVISYVASDIEGFITS
                     PLKIASFILLVFLSWKIGNRVNKNLENHNYDFHHKKHHNDKDDKMI"
     gene            complement(10938..11474)
                     /locus_tag="KRH23_003910"
     CDS             complement(10938..11474)
                     /locus_tag="KRH23_003910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HHS5227165.1"
                     /translation="MIKETHERGGYIFALLILPFINNLYLVKYDIAYKIVLIIIYIYF
                     AYLGSLFPDIDMRGSYISKKFMLIYKLFGSRFRHRGFTHSLIALLLIYSFFKSLTIFT
                     NNNIVFSCLSSGFIIGYLSHLCLDLITKEGIELFYPITINISLLPIKTNSKTEKFISK
                     LLNFIVIFLIGYQFYILL"
     gene            complement(11587..12291)
                     /locus_tag="KRH23_003911"
     CDS             complement(11587..12291)
                     /locus_tag="KRH23_003911"
                     /EC_number="1.15.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004784 - superoxide dismutase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006801 - superoxide metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HHS5227166.1"
                     /translation="MKKKILIPVIMSLFIISQCITSFAFTPENNKFKVKPLPYAYDAL
                     EPYIDKETMKLHHDKHYQAYVDKLNAALEKYPELYNYSLCELLQNLDSLPKDIATTVR
                     NNAGGAYNHKFFFDIMTPEKTIPSESLKEAIDRDFGSFEKFKQEFQKSALDVFGSGWA
                     WLVATKDGKLSIMTTPNQDSPVSKNLTPIIGLDVWEHAYYLKYQNRRNEYIDNWFNVV
                     NWNGALENYKNLKSQD"
     gene            12464..14338
                     /gene="asnB"
                     /locus_tag="KRH23_003912"
     CDS             12464..14338
                     /gene="asnB"
                     /locus_tag="KRH23_003912"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HHS5227167.1"
                     /translation="MDGNISIYYKGDISKKEDIKFKIKESVNNTRLSSRIEYKDEEKT
                     FDFERFNVIDAIYGNKPFEKDGKVIVFNGNIYNYHEIKEELIKKGHNFTTNDDIEVLL
                     ASYIEFGKNCVHKIKGMFNFIIYDRENESIFGARDLFGIKPLYYINKENAIIFSSEYK
                     FLLEYMKNLNINERSLQSYFSFQYVLPEDTMIQGIRLIPAGHYFRVENGILSLKRYNK
                     LEFRSSTKFFYTKNHLGNRDVNEDDIRNIVVDSIVTHMEEEKEIGTFLSGGIDSSIIT
                     TVASQINPNIKSFSAGFSVKGYSELEVAKKTADKLGIENIQINITQDEYIKSLPNVIY
                     SLDDPIADPSEVGLYFLIKEAGKHVKVALSGEGADELFGGYNIYKEYSTMKSVVNSPT
                     YIKSILGRVSELMPNIKGRNYLYRATTPLEKRYIGNAKVFENSEVKRFFFKYKEKNIY
                     EYLLSNLYRDAQKNNYDYISKMQHIDVNTWLQGDILQKISKLSTAEQVELRVPFLYKD
                     VFDVAKNLRMEQKINKNNTKVLLREAFREIVPEHVVQRKKLGFPTPIRVWLKDSLGDI
                     VKETIYNSNVDEFIDKKYAIKLLDTHLKGHRDNSRKIWTIFTFCLWHQLFIEHKNVEY
                     "
     gene            complement(14430..15866)
                     /locus_tag="KRH23_003913"
     CDS             complement(14430..15866)
                     /locus_tag="KRH23_003913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HHS5227168.1"
                     /translation="MICTIKPLKISIKKSTEPLIEFISDTTYKNKRSSYIKEVYFTRY
                     IGVDDSIDKYIEKIKNIDTYFFNNPTIPYIRLNNLKINFDKEQTDKMLKIFNIYNSSK
                     FNSWDLYNIDFPCKIENDTLNWTKKIAFKNTLDLFSTSMPNCTSSIIKNFAVKLLCWM
                     DYFLPKLFYNKVKTTISPKIVYFGNIKRQELFFLYFLSQLGCDILYINPNKDILDLYP
                     ECSKFSTLFELSRKTPNILEIPFERHITNINYSENTNKTSPTTNKPNSKNTLNNTNLT
                     SKKIVQDEEVELSYEDLAKLSASVVMIIVCNNENKPFKSGSGVVINNEGYILTNLHVV
                     NDGYSFLVRFENDDKVYTSYQIIKYHSDYDLAVIKVDRKCKPIPVKVSKKPVRGQKIV
                     AIGSPLGLFNTVSDGIISAFRDFETVQMIQFTAPISSGSSGGALLDMFGNLLGLISAG
                     YDDGQNLNLAVESSLVKIFANNFIEIVN"
     gene            16195..16773
                     /locus_tag="KRH23_003914"
     CDS             16195..16773
                     /locus_tag="KRH23_003914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006950 - response to stress [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HHS5227169.1"
                     /translation="MGITLSKGQKVDLTKGNPGLKNILVGLGWDTNKYDGGFDFDLDT
                     AAFLTGASGSVTNDGDFVFYNNLKHTSGAVEHLGDNRTGEGDGDDEQIVVDLSKIPGE
                     ISKISFTVTIHDATERRQNFGQVSNSYIRIVDKDTNEELIKYELGEDFSIETAIVVAE
                     IYKHNGEWKFNALGSGFEGGLAALCGNFGINL"
     gene            16812..>17199
                     /locus_tag="KRH23_003915"
     CDS             16812..>17199
                     /locus_tag="KRH23_003915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006950 - response to stress [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HHS5227170.1"
                     /translation="MAIVLKKGQKIDLTKGNPGLKNIKLGLGWDTNSFDSGYDYDLDV
                     SVFMVGESQRVEKDEDFIFYNNLKHPSGAVEHLGDNRTGEGDGDDEEILVNLETMPKH
                     IQKIAVTVTIYEAAERRQNFGQVSNSY"
BASE COUNT         6593 a         1869 c         2911 g         5826 t
ORIGIN      
        1 aaaaaaacgt atttattagt ggtaagtatg cttatagcgg gtttattaac tgcatgtagt
       61 gggagtccaa ctaaggattc aggacaagca caagataata caaaaaagga ggcaaatgca
      121 tcaaataacg ctttaaaaga tgaaaaaaat aatgaaaatt taatggaaca agattttaaa
      181 gtgccataca cagatgcaat aaacatattt aaagataaat ataaggatgc tgatatagta
      241 gatttaagtc ttgagagaga tttaaataaa tttgtttata ctgtggaagg tgtagatgat
      301 aataatgaat ataagatgaa aattgatgct aatacaaaag atgtattaga agataaaaca
      361 gaaaagttgg attcagaaga tttaaatgga gttgctagaa aagaaaaatt agatttaaat
      421 gacataatta aacctcaaca agctatggaa attgcattaa aagaacaaaa tggaatggtt
      481 aaagaatgga gtttagacaa agatttagat gttacttttt ataaaataag aatagataaa
      541 gataaaaatg aatatgacat aaaagtagat tctaaaaagg gaactgtatt gaaggtagaa
      601 aaagaagatt agaagattta aactatcttt aaaataattt cttttttgaa taaattttgt
      661 ttaaaatata acaagcaggg tataaagaga ctaaataact attttaggag gagtacggta
      721 tgtcattgaa atcactaaaa ataaaagaaa atttatattg ggtaggttca cttgaccctg
      781 atttaagagt atttgacata attatgtata caccttatgg gactacttat aattcatatg
      841 tattaaaagg aacagaaaaa acagttttat ttgagacagt taaagataag cattttgaca
      901 attatattga aagattaaat gatttaaata tagattttga aaaaatagac tatattgttg
      961 taagtcatac tgaaccagac catgcaggaa gcgttgaaaa gcttttggat ttagctaaaa
     1021 atgcaaaagt agtagcttca gaaacagcaa ttaaatatct taaggaaatc gtaaacaaag
     1081 actttgaata tgttgcagtt acagatggag atacattatc aattggggac aaaactttag
     1141 aatttttctc tgtacctatg cttcattggc cagataccat atacacatat ataaaagagg
     1201 ataaaactct tgtaacatgt gattcatttg gtagtcacta tagtaatgat aagatagtaa
     1261 atacacttga tgaaaatgaa gaaaaggatt acttggatgc tttaagatac tattatgatt
     1321 gtataatggg tccatttaaa ccatctatgg taactgctat agaaaagata aaagatttag
     1381 atatagatac tgtatgtcca ggtcatggtc cagtattaac tgaaaatcct agaaaaatta
     1441 tagaccttta ttacaactgg agtgtaaatg aacaaataaa gttagaaaaa gaagttacaa
     1501 tttgttatgt ttctgcacat ggatatacaa agattatggc agaagctata aaagcatata
     1561 ttgaaaaaaa tagcaactat aaagtaaatt tatttgatgt aatagagcat aagcaagaag
     1621 atattttggc aaaaatagca gtatcacaag gtgtattatt tggaacacca acaatattag
     1681 gagatgcgtt aaagcctata tgggatatat taatatcgtt aaacccagtt cttcatggtg
     1741 gaaaagttgc ttcagtattt ggttcatatg gatggagtgg agaaggtata gaaaatgcta
     1801 tggagagaat aagtcagctt agaatgacag cagtaaaacc ttttgctgtt aactttaaac
     1861 catcaaatga agagattgat aaattacatt cttatacagg taaattccta gataagttaa
     1921 attctacttt tggaagtaaa aagaaaacta agaaatttaa atgtgtaatt tgtaatgaag
     1981 tttttgaagg tgatagtgct cctagtgtat gccctgtatg tggagctaag gaagaccaat
     2041 ttatagaagt tgaagaagat gaagttactt ttagaaaaga tactgatgaa tatttcgtaa
     2101 tagtaggaaa tggagcagct ggtttttatg cagcagatgc tataagaaaa agaaataaaa
     2161 cttgtaagat aactatgatt tctaatgaag atgagttgac ttactataga cctgcacttt
     2221 ctgatggtat aaatgaagaa cttggttcag atttctacat ggaagataaa gattggtatg
     2281 ataaaaataa tatagtagta atattaggaa cgaatgtaga taaattagat gaagtgaata
     2341 aaactattat agtgaatgat ggagctatta aatttgataa gcttgtaata gctacaggaa
     2401 gtagaaactt tataccacca attaagggcc atgatttaga aaatgtgttt actcttagaa
     2461 atataaaaga tttatatagt gtaaaagaag cactagaaaa atctaagaaa gttgtagtga
     2521 ttggtggcgg tttattggga cttgaagctg catgggaatt tagactaaaa ggattagaag
     2581 tagtagtagt tgaagccatg gatagcatac tatcaaaaca acttgataaa gaaggtagta
     2641 aaatattaga acaatgtgta agagatacag gaatagatgt aagattgggt gtagcagttg
     2701 atggtattga aggtgatgga aaagctcaaa aagttgtatt taaagatgga gatagtgtcg
     2761 actgtgatat ggtagtattt tcaattggtg taagagcaaa cactcaaatg gttcaggata
     2821 catctgtaaa aattgacaga ggtattgttg tagataagac attacagaca aatattaaag
     2881 atatatatgc ttgtggagat gttgcacaag tgggaaatat tagtttagca atatggccat
     2941 cttcagtaga aatgggaaaa atagcagggg caaatgcaag tggagataat ttgacatttg
     3001 aaagtgaagt atatccagtt tcattagatg caatgaatgt aaaagtattt agtattggta
     3061 atatacaaaa ttttgataaa gaaatttcat caaaagatga aggtcaaaga atatataaaa
     3121 aattatttat gaaagatggt tcattagttg gagctatact tataaatgat ttaagctgta
     3181 ctgttaaatt gataagatta atatctgaaa aaggtgattt tgaggatatt atgaaggctg
     3241 atatactata atttaaatac attaaaataa aaaggagttg tctcaaaatt gatttttttc
     3301 taatcaaatt ttaaattcaa ctcctttttt gaatttttat ataaaataac atggaaattt
     3361 tagtaatgtc tgtggttaca tacataggtt taattgtttt ttatatggat tgtctctggt
     3421 ataataaatt gaattgtgtt tgactgatag atatttttat tgaaagttaa tacctgttat
     3481 gcgataataa ggacgtgtta ggggagtttt tataataaca attaatctca gtttttgtgt
     3541 tccaatggta gcatcaacac attctgatgt agtagttctt ttcttataaa aattagttac
     3601 aaatatgctt gtaattattt gatatgtaaa tttaccaata ttataaatga tgacctcgat
     3661 aataaggaga gtgaaaaata atctatgaac gaaaatattt tgattgtgga tgatgaaaaa
     3721 gaaatagcag atttaattga agtatattta aaaaatgaag gttttacagt atacaagttt
     3781 tatacaggta aggaagctct agaatgtatt gaatctaaaa atttggatat ggctatttta
     3841 gatattatgc ttcctgatat tgatggattt catatttgcc agaaaattcg agaaaaatac
     3901 tattatccta tcattatgtt aacagctaaa attgaagata tagacaagat aatgggttta
     3961 accataggtg ctgatgatta tataacaaag ccatttaacc ctttggaagt tgttgcaaga
     4021 gtaaagacac aattaagaag atatatgcga tataataatt cttatgaaca acagtcgata
     4081 attgttaatg agtatgatat taaaggattg attatcaata aagaaacaca taaatgtagt
     4141 ttatttggga aagaagtagc attaacaccg attgaatttt ctattctttg gtatttatgt
     4201 gaacatcaag gaaaagtggt tccttctgaa gaattgtttg aagctgtatg gggagaaaaa
     4261 tatcttgata ataataacac agttatggct catatagggc gattacgtga aaaaattcat
     4321 gaaccttcta aaaacccgaa atttataaaa actgtatggg gagtaggtta tacaattgaa
     4381 aagtaaaaat attaaagtca atcctgactt tactcaagtg agaaataaaa tttttatgag
     4441 aacagcttta atggcattta tagccattat tttcatatgg attttatatt cttttatatt
     4501 gtatggtaag ttttctatct ggatagtatc attctttgaa aatgcttttc gtatggaata
     4561 taaagctgca ttgaatttat atcagcagat tttccgtaat agcatggagc tcttcatgat
     4621 actagctatg gtgattgtgt tttttataat attccgtgtt tatttaaatt ggtttacaaa
     4681 atattttagt gaaataaatc aaggtattga ctctcttatc aaagaagatg ttggagaagt
     4741 ggctttatct ccagagttat tggcaataga aaagaaaata aactcaatta aacatatact
     4801 tgaacaacgt aaatttgaga cacaaatggc agaacaacgt aagaatgaac ttattgttta
     4861 tcttgcacat gatttaaaaa caccacttac atcagttata gggtatctga cactacttcg
     4921 agatgaaagt cagatttctg aagaactgcg aaaaaaatat ttatctattt cgttggataa
     4981 ggcagagcgt cttgaagatt taattaatga attctttgaa attacaaggt ttaatttatc
     5041 aaatatatca cttgaataca gtacagtaag cttaactcgt atgcttgaac aactaacata
     5101 tgagtttaaa cctactttga tgagtaagaa tttaaaatat acactgaatg ttacaccaaa
     5161 tatgatgata aggtgtgatg ttaataaaat gcaacgtgta tttgataact tattacgaaa
     5221 tgctgtttat tatagttttg aagatactac tattgaaata acagctgtac aggaggatga
     5281 ttatataaag cttaaattta taaattatag caatacgatt ccagaggaaa aacttgagcg
     5341 tatttttgaa caattttaca ggttggatac atctcgtaat tcaaacagtg gtagagctgg
     5401 gttgggactt gctatagcta aagaaatagt ggagcttcat aacgggacaa taacagctca
     5461 tagcgagaac aatataatta cctttaaggt tattattccg attgtaggaa atttgtaaga
     5521 atttaagtat aaaaaaatag gaaattcttt aggataaata aataaagagc actcttgtta
     5581 ttgatataat tactgtatca aaacaagagt gcttttattt tgatacagta attatatcaa
     5641 tagaaaaatg tgaaaatata ttatgtggaa cagatgcaat tgtaagtgaa ggttgattgg
     5701 atttgaaata gaaaaagtat tttaacatgt ttctgtagat tgtataaaaa taaataaatc
     5761 aacaaaggag aatcaaagat gaataataaa aaaattgcag ttatatttgg tggaaactca
     5821 acagaatatg atgtatcatt acaatcagct tttgcagtac ttgagaattt gaatacggaa
     5881 aaatatgata ttataccaat tggaattaca agggagggta attggtatca ttatattgga
     5941 gattataata atatccagaa taacacttgg tttgaaaggg atactgatat aattccagtt
     6001 attgtttcgc agaaccgtgt caaaaatggt attattgaat ttttaattcc tgatgctgtt
     6061 tctcagaatc atattccaaa tagtgctatt gaatcatgtg aaaatgatat taaatacact
     6121 aaacttgatt ttgtatttcc tgtattgcat ggaaaaaatg gagaagatgg aacagtgcag
     6181 gggttatttg aattggcagg tatacaggtt attggatgtg gtactctttc ttcagcatta
     6241 tgtatggaca aagacaaatc acataaactt gttcattcag aaggtattaa agtaccaaaa
     6301 tcaatattac taaaatactc agataaattt aatgtggctg aactgtcaaa agacttaact
     6361 tatccattat ttataaaacc tgtgcgtgca ggttcatcat ttggtattag taaaatttat
     6421 aaaaaagaag agttacaagt agcagtagac ttggcttttg aacatgataa tgaagtaata
     6481 attgaggaaa atattgatgg ttttgaggta gggtgtgcag ttttaggaaa caatgactta
     6541 cttgttggaa gagtagatga aatagaattg tcaaaaggat tttttgatta tacagaaaaa
     6601 tatacattga aaagttcaaa aattcatatg ccagctagaa ttgatttgga ttgtgagaaa
     6661 agaatacaag agacagcaaa aattatttat agaactcttg ggtgttctgg atttgctaga
     6721 gtagatatgt ttttaactcc atctggtgaa attattttta atgaagtcaa tacaattcct
     6781 ggctttactt ctcatagtcg ttatccaaat atgatgaaag gtattggatt gtcttttgaa
     6841 gaaatattgg acaagataat tgaggtgtac ataaaatgat gaataatatt ttattagata
     6901 aaaataaaga agataaaatg acaaatacta tcttattgac taaagataaa gtttatgatg
     6961 ggaatctaat tctagtaaat gcttttttac cagttaaaac atctgaagat atagatttaa
     7021 ttcctgtaga tacaaggttt ccaagtattc ttatgaaacg tgaagctaca aacattttac
     7081 aaaatatttt aaaaagtata tgtggaataa atgaaatagt acctgtaagt ggatatcgta
     7141 ctgcagagga acaacaagat atatattcaa gttctctgcg tgacaatgga aaagacttta
     7201 ctaaaaagtt tgtagcactt ccaaatcaca gtgaacatca gacagggctt gctattgatt
     7261 tagggttaaa gaaagaagtt atagatttta tctgccctga atttccttat aatggtattt
     7321 gtaatgagtt tcgtaaggca gcactacatt atggttttat agagcgttat cagtgtaaaa
     7381 aagaagaaat aacaggaata tctcaagaac catggcattt tcgttatgtg ggatatccgc
     7441 attctgagat tatcaataaa atgaatctcg ctcttgaaga atatatagaa tatattaaga
     7501 gattttcgta tacaaattgt ttaaaaatag aagataaaga aaaaattata gaaatctttt
     7561 atgtgcctat ccatactaaa gaagaagtga gaatctctat acctgaacaa tgtgtatatc
     7621 aaatatcggg taacaataag gatggtttta ttgtgacatt ttggagaaat agaaaggact
     7681 aagaaatgga ggaacaagaa tgattaggaa taaatcttat gcagggcttg attattttag
     7741 gattatagct gcattactta taattgcaat tcatacatct ccattattat catatagtaa
     7801 aatggctgac tttgtgttaa ctagtataat tgctcgtatt gctgtgccat tcttttttat
     7861 gctatcaggc ttttttctaa tttcaacata taattataat tgtaataaac tgaaatcttt
     7921 tctaaaaaat gtattattta tttacgggat agctattgta atttatattc ccttaaatat
     7981 ttacactgga tatttttcca tgaataattt agtgcccaat attattaagg acattgtatt
     8041 tgatgggact ttatatcatt tatggtatct tcctgcatca attattggtg caagtattgc
     8101 atactttctt gtaaaaaaac taggtttaaa gtactcacta gtaatcacta ttgttattta
     8161 tgtaattggt atgtttggtg atagttatta tggtttttta gaaaaaatac cactattaaa
     8221 gaatttatat gggtatattt ttgaagtatc agattataca cgaaatggta tattttttgc
     8281 acctgtattt ttcatacttg gtggaataat atctaataaa tctaattata tgtcaactaa
     8341 aaatagcttg attggatttc ttatatcatt cttacttatg ttatgtgagg gaatgttttt
     8401 acataaacta ggggtacagc gtcatgatag catgtatatt atgttattgc catgtatgta
     8461 tttcttattt acagccttaa catttttgaa aggttctcga gctaggttat tgcgaacatc
     8521 atcattaatt atttatatta tacatcctat gatgattgtt gttattcgta tgttttctaa
     8581 aatattcgga atacaaactg tcttggttga caatagcctt attcattata tagtggtaag
     8641 tatagcatct tttatagctt ctataattat tatattgatt cttaaacctc taaaaaaata
     8701 cttgaaagga gaacataagg taaataccaa tagagcttgg attgaaattg atttaaataa
     8761 tttggaacat aatgtaaaga tgatacaaaa agctatgcca gaagattgtg aattgatggc
     8821 agttgtaaaa gctaatgcct atggtcatag tgcttttgaa gtagcgactt gtgcaaacca
     8881 aataggtgta aaagcatttg cagtagcaac aatagatgag gggattgatt tacgtcgata
     8941 tggaatacta ggagaaatat tgattcttgg atatactaac ccaataaggg caaaggaact
     9001 tcataaatac aatcttacac agagtgttat tgaccttaat catgctatct ctttaaacaa
     9061 acagaaatac aacataaaat cacacattaa aattgataca ggtatgcaca gactgggttt
     9121 tgatgttaat gatgtgaggt caattttaaa ggcatttaaa ttaaaatact tagatatatg
     9181 tggcatattt acacacttgt gtgtttcaga tagtctgaaa gatgaagatg tagactttac
     9241 aaataaacaa attgaatgtt tttataagtt aattgatttt ctgttaaaaa aaggtataaa
     9301 aattcataaa gtacatattc aaagtagtta tggttttttt aattatccca atcttaagtg
     9361 taattatgta agaattggaa ttgcattata cgggatatta agttctccaa atgatacgac
     9421 taaattgcaa cttgatttac gacctgtttt atccttaaaa tcacaagtaa ttcttattag
     9481 aaaaatacaa aaagatgata gttttggata tggaagagtc tttattgcaa gcagagatag
     9541 cgtaattgct atattatcta ttggctatgc cgatggtata cctagaaatt tatcctgtgg
     9601 aaaaagttac gtaataataa atgattgtag agcagcaata gtgggtcgaa tttgcatgga
     9661 ccaacttgct gttgatatta cagatatacc taatgtagaa gttggtaata cggcaataat
     9721 aataggaaga gataatttag ctgaattatc tgcttctgaa gttgcaaata actcatgtag
     9781 tatatcaaat gaattattga gcagagtagg aagaaggtta aatgttataa agaagtaact
     9841 caattaaata gtaatatttg ttgtactgtg taatttattt tactctgact agacattttt
     9901 agtaatatta tgtctaatat atatttttta taacttacat gacaatttaa gttataaaaa
     9961 ggtgatgttt cagattttta ttttgaaaca tcaccttttt tgttataata tataataaaa
    10021 taattatacc ttaactgtaa acttatatag attatttact ttttaatatt agattcattt
    10081 tttgagattg gtatataata aacatataga gtatataata atagttaaag ttaaaaaagg
    10141 ggaaaagcaa tatgcagtat atacaagaac tacttgattt gactcaaaat tattgggtgt
    10201 tagccacaat aatcggctta ttaagtgcat ttatagaaag ctttatacca gccttaccac
    10261 ttgttgctat agttacagca aatgctgcaa tacaaggatt atttattgga tgtttgttat
    10321 catggattgg ctcaggactt gggacaactt cattattctt attaataagc agatttaatg
    10381 atagtaagct ttttaataag ttgagaaata gtaaaactga aaaagcaata agttggatgg
    10441 ataaacaggg atttaagtta ttatttatag cgtatgcctg tccatttatg cctggttgtt
    10501 tagttactat cgcatcagct tttggtaaaa aagatttaaa agattttgtg ccagcaatgt
    10561 tggcaggaaa atttgtaatg tttatagtta taagttacgt ggcaagtgat atagaaggtt
    10621 ttataacaag tcctttaaag atagcatcat ttatattatt ggtgtttttg tcatggaaga
    10681 ttggaaatag agtaaataaa aatcttgaaa atcataatta tgatttccat cataaaaaac
    10741 atcacaatga taaagatgat aaaatgattt agcttgtacg aaataaaacg tatcttaaaa
    10801 tgatttagta ctaaattatt ttaagatacg ttttattttt tgtattaagg tacaaaattt
    10861 ttagttcttt tgtaaactaa aatatataaa acttatttat acttagttca aaatattgtt
    10921 atttattttt tctacaacta taataaaata taaaattgat atccaatcaa aaaaataact
    10981 atgaaattta atagcttaga tatgaatttt tctgtttttg agttagtttt tataggtagt
    11041 aaagaaatgt ttatggtaat gggataaaac aattcaatac cttctttagt aataaggtca
    11101 agacacaagt gagatagata tcctattata aacccactgg acaaacatga gaaaactata
    11161 ttattgttag tgaagattgt cagagattta aaaaaactat aaataagtaa taaggcaatt
    11221 agactgtgag taaaccctct atgtctaaac ctacttccaa ataatttgta tattaacata
    11281 aattttttac ttatgtaaga acctctcata tctatatctg gaaataaaga acctaaatat
    11341 gcaaaataaa tataaattat aattaatact attttatatg caatatcgta tttaactagg
    11401 tacagattgt ttataaaggg gagtatcaaa agtgcgaata tataacctcc cctttcatgt
    11461 gtttctttta tcatataaaa atcctcctga atcgtcacta taaacattat attggtaaat
    11521 ttagactatc ttttattata ttatatagca aacataagtt tttttcaaaa ggattttaat
    11581 atttaattaa tcttgagatt ttaaattttt gtaattttct aaagcaccat tccaatttac
    11641 tacattaaac cagttgtcaa tgtattcatt tcttctattt tgatatttta aatagtaagc
    11701 atgctcccaa acatcaagtc ctattatagg agttaggttt ttacttacag ggctatcctg
    11761 atttggagta gtcataatag ataatttgcc atctttagta gctacaagcc aagcccaacc
    11821 agaaccaaag acatctaaag cagatttttg gaactcttgc ttaaattttt caaaagaacc
    11881 aaagtctcta tcaatagctt cttttaaaga ttcagaaggt atggtttttt ctggcgtcat
    11941 tatatcaaaa aagaatttat gattataagc tccacctgca ttatttctta cagttgtagc
    12001 aatatcttta ggtaaagaat ctaaattttg caataattca cataaagaat aattataaag
    12061 ctcaggatat ttttcaagag cagcatttaa tttatcaaca taagcttgat aatgcttatc
    12121 atgatgcagt ttcattgttt ctttatctat ataaggttca agtgcatcat atgcataagg
    12181 taatggttta accttaaatt tgttattttc aggtgtaaaa gcaaatgaag ttatgcactg
    12241 tgagattata aataaagaca taataactgg tattaatatt tttttcttca taaaaatcac
    12301 ctcctaatat agtatttcta gaaataaaaa aaatatgaaa tattaacaga taatttataa
    12361 gaatttaata gcaatttcat tttaaattga ataagtttta aagccaaaga caaaactatg
    12421 aaatatagaa taagactaaa ggacagaaag gaattttgat tatatggacg gcaatatttc
    12481 aatttattat aaaggtgata tatctaaaaa agaagatatt aaatttaaaa taaaagaatc
    12541 tgtaaataat acaagacttt ctagtagaat agagtataag gatgaggaaa aaacttttga
    12601 ttttgaaaga tttaatgtaa ttgatgctat ttatggaaat aaaccatttg aaaaagatgg
    12661 aaaagttatt gtttttaatg gaaatatata taactatcat gaaataaaag aagaattaat
    12721 taaaaaagga cacaatttta ctacaaatga tgatattgaa gtcttattag catcttatat
    12781 agaatttggt aagaattgtg tacataagat taaaggaatg ttcaacttta taatctatga
    12841 tagagaaaat gaaagtatat ttggagcaag agatttattt gggataaaac cactttatta
    12901 tataaataag gaaaatgcaa taattttttc ctcagagtat aagtttttac ttgaatatat
    12961 gaaaaattta aatataaatg aaagaagctt acaaagttat ttttcatttc aatatgtact
    13021 tcctgaagat actatgatac aaggaataag gctgatacca gcaggtcact attttagggt
    13081 agaaaatggt atactatctt taaagagata taataaactt gagtttagaa gtagtacaaa
    13141 atttttttat actaaaaatc acttaggcaa tagagatgtg aatgaggatg atataagaaa
    13201 tatagtagta gattcaatag taactcatat ggaagaggag aaagaaattg gaacattttt
    13261 gtctggtgga atagattcat ctattataac tactgtggct tcacaaatta atccaaatat
    13321 aaaatctttt tctgcaggct ttagtgtcaa aggatatagt gaattagaag tagcaaagaa
    13381 aacagctgat aagttaggta tagaaaatat ccagattaat ataacacaag atgaatatat
    13441 aaaatcatta ccgaatgtaa tttattcttt ggatgaccct atagcagacc cttcagaagt
    13501 aggtctttat ttcttaatta aagaggcagg taaacatgtt aaagtagcat tgtctggaga
    13561 aggagcagat gaattatttg gaggatataa tatatataaa gagtatagta ctatgaaatc
    13621 agttgtcaat tcacctactt atattaaaag tatattagga agagtttcag aacttatgcc
    13681 aaacataaaa ggaagaaatt atctttatag agctacaaca ccattagaaa aaagatatat
    13741 aggaaatgca aaagtttttg aaaacagcga agtaaaaaga ttctttttta agtataagga
    13801 aaagaatata tatgaatacc tgttgtctaa tttgtataga gatgcacaaa aaaataatta
    13861 cgattatata agtaaaatgc aacatataga tgtgaataca tggcttcaag gcgatatact
    13921 tcaaaaaatt agcaaacttt ctacagctga gcaggttgaa cttagagtac catttttata
    13981 taaagatgta tttgatgtcg caaaaaattt aagaatggag caaaaaataa ataagaataa
    14041 tacaaaagtt ttacttagag aggcgtttag agaaatagtc ccagaacatg ttgttcaaag
    14101 gaaaaaatta ggatttccaa ctccaataag agtttggtta aaagattctc taggggatat
    14161 tgtaaaggaa actatttata attcaaatgt agatgaattt atagataaaa aatatgcaat
    14221 aaaactttta gatacgcatc ttaaaggtca tagagataat tcgagaaaaa tatggactat
    14281 atttacattt tgtctatggc atcaattatt tattgagcat aaaaatgtcg agtattaata
    14341 cttttttcaa tattaatcag agggcaaaag catgcaatgt tttcaccctc ttgattatta
    14401 tggaatagga taagtagaat tttgattgat tagtttacta tctcaataaa attattggca
    14461 aatattttga caagactact ttcaacagct aaatttaagt tttgtccatc atcatatcca
    14521 gcggaaatca atcctagtaa gtttccaaac atatctaaaa gagctcctcc tgaactacca
    14581 ctagagattg gagctgtaaa ttgtatcatt tgaaccgttt caaaatcacg aaaagctgaa
    14641 ataattccat ctgaaactgt attaaaaaga cctagagggc ttccaattgc aactattttt
    14701 tgacctctca caggtttttt actgacttta acaggtattg gcttgcattt tctatcaacc
    14761 tttatcacag ctaaatcata atctgaatgg tattttataa tttggtaaga tgtataaact
    14821 ttatcatcat tttcaaatct aactaaaaat gaatacccat cattgactac atgaagattc
    14881 gtaagtatat aaccttcatt atttattact actccagaac cgctcttaaa cggtttattt
    14941 tcgttattgc acacaataat cataacaaca gaagctgata actttgcaag gtcttcataa
    15001 gaaagttcta cttcctcatc ttgtacaatt tttttagatg ttagatttgt gttattaagt
    15061 gtatttttag agttaggttt attcgtagta ggagaagtct tattggtatt ttcactgtaa
    15121 tttatatttg taatatgcct ttcaaaaggt atttctaata tatttggagt cttcctagaa
    15181 agttcaaata gagtagaaaa ttttgaacat tcaggatata aatcaagaat atctttattt
    15241 ggatttatat ataaaatatc acacccaagt tgtgataaaa aatataagaa aaaaagttct
    15301 tgccttttaa tatttccaaa gtatactatc tttggtgaaa tagtagtctt caccttgtta
    15361 taaaataatt taggtagaaa atagtccatc caacacaaaa gtttaactgc aaagtttttg
    15421 atgatagagg atgtacaatt tggcatactt gtggaaaata aatctaaagt atttttaaat
    15481 gcaatctttt tagtccaatt taaggtgtca ttttctattt tacatggaaa gtcgatatta
    15541 tataaatccc aactgttaaa cttagaacta ttataaatat taaaaatttt aagcatctta
    15601 tctgtttgtt ctttgtcaaa atttattttt agattgttta atctaatata gggaattgta
    15661 ggattattaa aaaaataagt atctatattt ttaatttttt ctatgtattt atcaattgaa
    15721 tcatcaacac ctatatatct tgtaaagtag acttctttaa tatatgaaga acgcttattt
    15781 ttataggtag tatcagatat aaattcaatt agaggttcag tagacttttt tattgaaatc
    15841 tttaatggtt taatagtaca aatcatattt tttctcctat aataagatga tataatctat
    15901 tataaaacaa cttaaaacaa tatagtacaa taattttgta gtttcaaaat aaaatatgta
    15961 cttgtttata taaatgatat ataattacat attaaacata gcttttatgc atttaataaa
    16021 gtatgtaaaa tctatgtaaa aagtaagaaa tataaacatt tttttaatta tattttaaaa
    16081 atatcaagca agttttattc acaaatgaat aaaaaatgtt ataatatgat taaagaaaaa
    16141 gataaataat tagcaagatt tgtttagcta aaattaacaa gggagcgata aattatgggt
    16201 ataacattat caaaaggcca aaaggttgat ttaactaaag gaaatccagg tcttaaaaat
    16261 attttagtag gtttaggatg ggatactaac aagtatgatg gtggatttga ctttgattta
    16321 gatacagcag catttttaac aggagcaagt ggaagtgtta ctaatgatgg agattttgta
    16381 ttttacaaca atttaaaaca tacatctgga gcagttgagc atctaggaga taacagaact
    16441 ggcgaaggtg atggagatga tgaacaaata gttgttgatt tatctaagat tcctggagaa
    16501 ataagcaaga tttcttttac tgttacaatt catgatgcga cagaaagaag acaaaatttt
    16561 ggacaagtaa gtaattctta tataagaata gtagataaag acacaaatga agagttaata
    16621 aagtatgaat taggagaaga ttttagtata gaaacagcta tagtagtagc tgaaatatat
    16681 aagcacaatg gagaatggaa gtttaatgca ctaggttctg gctttgaagg tggtcttgct
    16741 gcattatgtg gaaactttgg aataaactta taatttcaac tataacaata aactaaaggg
    16801 ggatattttc catggctata gtattaaaaa aaggacaaaa aatcgattta actaagggaa
    16861 atccaggtct taaaaatata aaacttggac taggatggga tacaaattca tttgatagtg
    16921 gctatgatta tgatttagat gtaagtgttt tcatggttgg agaatctcaa agagttgaaa
    16981 aagatgaaga ttttatattc tacaataact taaaacatcc atctggagca gttgaacact
    17041 taggtgataa tagaactggt gaaggtgatg gagatgatga ggaaatatta gtgaatttag
    17101 agacaatgcc aaagcatata caaaagatag ctgtaacagt tacaatatat gaggctgctg
    17161 aaagaagaca aaattttgga caagtaagca actcatata
//
LOCUS       DAEORM030000186        16201 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.guided.075, whole genome shotgun sequence.
ACCESSION   DAEORM030000186 DAEORM030000000
VERSION     DAEORM030000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 16201)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16201)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 16201)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16201
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.guided.075"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            complement(208..732)
                     /locus_tag="KRH23_003916"
     CDS             complement(208..732)
                     /locus_tag="KRH23_003916"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HHS5227171.1"
                     /translation="MENKNPIVTIEMENGKEIKIELYPNIAPNTVKNFVSLVNEGYYN
                     GIIFHRVIPGFMIQGGCPNGTGMGGPGHSIKGEFSGNGFTNNLKHERGVISMARTMAP
                     NSAGSQFFIMHKNSPHLDGQYAGFGRVIEGMDTVDEIASVRTDSADKPQTPQIMKSVT
                     VETFGIDYSDVEKN"
     gene            complement(797..1549)
                     /locus_tag="KRH23_003917"
     CDS             complement(797..1549)
                     /locus_tag="KRH23_003917"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052689 - carboxylic ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HHS5227172.1"
                     /translation="MKLGLCLEGGGAKGAYQAGVVKALYDGGINKFYSISGTSIGAIN
                     GYYLYTGNVDNLEKMWTNIKDIQNGNVKIVNNTVDNSPAIDNLRELDDSNIEEMNFYV
                     NYVEVDNKVVSEKIVDVSKMPRNEAIISISYSGLLPSNPNATLGFKEQFVKDVQEGIY
                     DGFKLDGGLIRSALIEPLIGDNVDKIILISTKYNYELPEDIKKVYDEDKIIVVRPNTQ
                     FAPKDTLNFDDEFCKTIYQEGYEIGKNILDRL"
     gene            complement(1580..2878)
                     /locus_tag="KRH23_003918"
     CDS             complement(1580..2878)
                     /locus_tag="KRH23_003918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004177 - aminopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M18 family aminopeptidase"
                     /protein_id="HHS5227173.1"
                     /translation="MDSINFAKNLIDFIYDSPSSFHAVESTKEILDKNGFEELVLNQR
                     WNLRVGGKYYVTKNLSAIVAFVVNSEGIERDGFRIIGSHSDSPTFSIKPNAEIEAEKS
                     YLKLNTECYGGAILSTWLDRPLGIAGRVVLKGDSILKPNERLIDFKKPICIIPNLAIH
                     LNRSINDGHSYNKQKDMLPLVGMLNDTLEKDNFLIKQIASNLDVNMEDIIDFDLFLYE
                     FEKGSLIGANDEFISIGRQDNLAMVHASLNALVNTKGQHGVNVMAVFDNEEVGSSTKQ
                     GADSNMLLNILERICISMGKDREGFFESIYSSFMISSDLAHAIHPNIPEKHDPTNKPI
                     MGKGPVIKINASQAYTSDGYSIAIYKNICREANVEYQEFVNRSDERGGSTIGPISSTH
                     IDIPSVDVGSPILAMHSIRELGNVEDHYSIYKTFSKFFEI"
     gene            complement(2895..5159)
                     /locus_tag="KRH23_003919"
     CDS             complement(2895..5159)
                     /locus_tag="KRH23_003919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3553 domain-containing protein"
                     /protein_id="HHS5227174.1"
                     /translation="MNLDTLNPAQREAVEKTEGPVLILAGAGSGKTKVLTTRIAYLIE
                     DKGVQAPNILAITFTNKAANEMRERVEQNIGPETKDMWISTFHSCCVRILRKDINKIG
                     YNRSFVIYDSADQVTLVKDCLKELNLSDKVFEPKAVISAISGAKDKLYTPKQFKDINM
                     ADNRMVKIADIYALYQDRLKRNSALDFDDLILKTVELFKANDEVLAYYRSRFRYIMVD
                     EYQDTSKAQYELIKLLAREHQNICVVGDDDQSIYGWRGADIRNILEFEKDYDNVHVVK
                     LEQNYRSTQVILDAANKVISNNIERKRKKLWSEKKEGELIKIQLTGSEIEEADFIADS
                     IAQIARKENRPYKDFAVLYRANAQARPVEDALNRSQIPYNIYGGTKFYERKEIKDLLA
                     YLRVIQNPQDDISIKRIINVPRRGIGLRTIEKIEDRANLKQESIYSVLIDIETNSDIS
                     TKARASISGFVDIIGTLRTIKEVYPVSKLIEKVLDTTGYMDELVEIRNKNEKDLTGKG
                     EEAQDRIDNLREFISIALEFESSNDDTYENKDLETFLTSIALTSESNDEEDNDRVSLM
                     TIHTSKGLEFPVVFLTGMEEGLFPISRAIKSMSDSQIEEERRLCYVGITRAKEELYMS
                     LTEKRTLYGKTNVAIASRFMEELPEECIERLYKVKKELSYSKASYNMLDKYTKKYMST
                     ISKSKVADKVNATIKDSNKETNPDDIKLGSKVHHPKFGVGTVVSIIGTDVTIAFDQQG
                     IKKINKEYTTLNIL"
     gene            complement(5414..6232)
                     /locus_tag="KRH23_003920"
     CDS             complement(5414..6232)
                     /locus_tag="KRH23_003920"
                     /EC_number="3.6.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HHS5227175.1"
                     /translation="MFKINNLTYQYEKNTNALLNINMDFSKGNVIGIIGSNGSGKSTL
                     FMNLMGILKPTSGEILFKEEKLKYDKRSLYNLRKNVGIVFQDPEKQIFYSKVYDDIAF
                     AMRNIGMDEKTIKERINKALVAVNGIDFIDRPVHFLSYGQKKRVAIASVIAMENEIVL
                     LDEPTAGLDPVSTRSIVDIIKGLNKNNIKIVISSHDMNLMYEICDYIYVLDKGILIDE
                     GKAENVFINENNIIQAGLESPWLVKVHRNMNLPLFKKEEDLYKYWKERELNTNK"
     gene            complement(6225..6923)
                     /gene="cbiQ"
                     /locus_tag="KRH23_003921"
     CDS             complement(6225..6923)
                     /gene="cbiQ"
                     /locus_tag="KRH23_003921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0032778 - P-type cobalt transporter
                     activity [Evidence IEA];
                     GO_process: GO:0006824 - cobalt ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ECF transporter T component CbiQ"
                     /protein_id="HHS5227176.1"
                     /translation="MLIIDKYAYTNRLSKVNPNKKVAIGVIFLIASMVIQNIFILSGI
                     MILMSILVVCVAGIDLKNYLKLLRIPMYFLFLSIGITLVNISFNKADLLYSFEFFSFN
                     VGISKASIDMSIHVLFRAMSCLTCVYFCILTTPFNQLIFFFKKLHLPDTFVELSMLIY
                     RFIFIFLEEFSEIYKSQELRFGYINLKTSYKSLGILGSMLYKRLMTRYDDMCISLDIK
                     LYDGKFHIVGDNDV"
     gene            complement(6926..7210)
                     /locus_tag="KRH23_003922"
     CDS             complement(6926..7210)
                     /locus_tag="KRH23_003922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015087 - cobalt ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006824 - cobalt ion transport [Evidence
                     IEA];
                     GO_process: GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     substrate-binding protein"
                     /protein_id="HHS5227177.1"
                     /translation="MSAKTKTKTNILLLLLVVALIIFPLLVNSGAEYGGADGQAESEI
                     TKINPNYKPWFSSPYEPPSGEIESLLFSAQAALGAGVIGYILGLQKGKRS"
     gene            complement(7200..7952)
                     /locus_tag="KRH23_003923"
     CDS             complement(7200..7952)
                     /locus_tag="KRH23_003923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_process: GO:0000041 - transition metal ion transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter permease"
                     /protein_id="HHS5227178.1"
                     /translation="MKQNIKLGVIAALMLIILTPVTSNAMHIMEGYLPVKWSIAWGVI
                     FIPFFLFGLKSIGKIVKQDPKKKVLLALCGAFVFVLSALKIPSVTGSCSHPTGVGLGA
                     IMFGPSVMFVLGTIVLIFQALLLAHGGITTLGANAFSMAIIGPIVSFLIFKALKKKDG
                     NNAMPVFLAAAIGDLATYTITSIQLALAFPDPSGGVMASAIKFLGIFFMTQIPIAIAE
                     GILTVIVYNLITENGEKSILENNDKGVKANEC"
     regulatory      complement(8135..8326)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
     gene            complement(8458..10230)
                     /locus_tag="KRH23_003924"
     CDS             complement(8458..10230)
                     /locus_tag="KRH23_003924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitric oxide reductase activation-like protein"
                     /protein_id="HHS5227179.1"
                     /translation="MKWIYDDYEFENRANNLSWTIAGDYNESIDISEKDYSSKEIGLY
                     FAIIAGARRKYVDWDIVKKYLTNRIRKGYNKDIILGLIQVILNTIVEEKVIKDRPGIE
                     DIRRNAYKDIVSRFTKIHNDNIMDKIKYTFVLYSMDKHPALDSMTRRIVNDIRNIDTN
                     QDIMEILKALDVIYLTYFEYILNGEENSLIDENNVESVEVNFDTFADFMYEELYSDEE
                     ENIIESDIDSISSSMLVEGVGDFDDSKCNNSADRVIYVDEDTANKIYSKIEHYYGKTY
                     LSKGEIKKIETQNCRNVHEGCRIHFTDGVLRSECNNVFQLKYVTRQKENNLGKFREHA
                     RMYRQQIKRLKESLSRILIEENAKSRVYSDCGTILANRAWRVGRSNNNKIFYKDIENE
                     KGKYVIDILLDASGSQSRNQGNVAIQAYIIANALTEVGIPNRVMGFSSFLDYTILKRF
                     KDYDDSIKNSENIFEYFCAGNNRDGLAIKSICSGLINRDEENKILIVLSDGRPNDVKI
                     GKSSERTLRGEKAYRGIVGLRDTANEVRKARKQNILVLGVFTGKESELEAERLIYGND
                     FIYSRDITRFSDVVSMYLKKIIRN"
     gene            complement(10244..11173)
                     /locus_tag="KRH23_003925"
     CDS             complement(10244..11173)
                     /locus_tag="KRH23_003925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HHS5227180.1"
                     /translation="MDIIDNLRVQGVDEKLIEDVLYFRNYYGLEKDLEYRVTKSKTYF
                     YGKDILSMCIAAILEEENILLSGPKATGKNLLADNLGEIFNRPQWNTSFHINTDSSTL
                     IGTDTFIDNEVKLRRGSVYECAINGGFGVFDEINMAKNDAIVVVHSALDYRRIIDVPG
                     YERVNLHPATRFIGTMNYEYAGTKELNEALVSRFMVIDIPPIEEDKLMMILKNEFSDA
                     DEEKLIHFAGIFLDLQLKSQNGEISSKAIDLRGLMASLKTIRRGLKPTLAINMGLTGK
                     TFDVYEKEMVGDVIKTRIPNKWESIDVFPISHI"
     gene            11402..11590
                     /locus_tag="KRH23_003926"
     CDS             11402..11590
                     /locus_tag="KRH23_003926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHS5227181.1"
                     /translation="MEYMSCPEVAKKWGISERRVQKLCEESRIPGVSKLGYMWLIPKN
                     AEKPVDGRTKRRKEVQYE"
     gene            11583..12284
                     /locus_tag="KRH23_003927"
     CDS             11583..12284
                     /locus_tag="KRH23_003927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HHS5227182.1"
                     /translation="MNSVLIIDDDKELCALMKKCVEQENLSAITAHCGAEGLHLVDKN
                     RHTLSLVILDIMMPDIDGFQVLKKIRETSNIPVIMLTAKNDEDDKVSGLRLGADDYLT
                     KPFSINELMARVNSLIRRYTMLNPAFITDTDCIIINGMIIDKTNRIVSVNNIPVQLTS
                     KEFDLLAFLASNKGRVFTKKQIYTQVWEEEYAFDDSNIMSFISKLRKKIEPDPNHPFY
                     ILTVRGVGYRFNKEA"
     gene            12286..13209
                     /locus_tag="KRH23_003928"
     CDS             12286..13209
                     /locus_tag="KRH23_003928"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HHS5227183.1"
                     /translation="MNTSVYLLLILALSLIIIAYLVSVLLRVRIQLTLIKDALEDIKN
                     GNLNRRILTDENDITKQICYDINEIAINSQFQLIQQKQSEQAYKQLMTSLSHDVKTPL
                     ASLVGYLEAVESKIVVGEEKDEYIHVASNKAHYLKNFVENLFEWVKLDSKEQVFHFDI
                     FDLNELSRNIISDWIPVLESSHFEYEFDIPEIEYFLRIDANAYTRIINNLLQNIITHS
                     SGNKMTLRIFENKEQAQIIITDNGKGISSDNLPHIFERLYQCDHSRASKGNGLGLAIA
                     KELINAHKGNITANSTPGMGTEFTILLPKAL"
     gene            13366..14289
                     /locus_tag="KRH23_003929"
     CDS             13366..14289
                     /locus_tag="KRH23_003929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019639192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHS5227184.1"
                     /translation="MNDFVIETKQLTKIYGNQTVVDKVNLHVKKGRIYGLLGRNGAGK
                     TTIMKMILGLTSITYGEVDVFGENIKGREKQVYPRIGAIIETPGFYPNLTGTENLEIF
                     AKLRGTAAPNSVKRALEIVGLPYKNKKLFSKYSLGMKQRLGIANAILHDPELLVLDEP
                     TNGLDPIGIAEMRKFIRDLSVEHGKTILISSHILSEISLLADDIGIIDHGVLLEESSM
                     SELEKKNSKYILLQVSDIPKTSLILERQFNTKDYSVQDDYTLHLYNTNLDMGEINKAL
                     VMQNVIVISSQLCNDTLEDYFKKITGGEGIA"
     gene            14282..15019
                     /locus_tag="KRH23_003930"
     CDS             14282..15019
                     /locus_tag="KRH23_003930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHS5227185.1"
                     /translation="MLKLIQTEFLKLRRRKLIWLMLLSALIMPFFALLYFNYFGKTGV
                     EPTKFYKWSAFGYTLWIILPVVLGIFCTMLIHEENQYDMLKQLWIVPISKMGYFFSKF
                     FVVLIYSICFMLITAVASVLFSVLSGYVVFSWASILYLLKKCLEIGVITAFVMLPILA
                     IATSQKGYILPICITLVYAFSGFVIMTINMYLHPLSSMGVIIMRNKDIPGLIFSQEIN
                     VPLAFLCICIWSIVSVLFANIALGRRK"
     gene            15030..15803
                     /locus_tag="KRH23_003931"
     CDS             15030..15803
                     /locus_tag="KRH23_003931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHS5227186.1"
                     /translation="MWKLLWAECQKIRRSKIVWITVFASIMIAVIVFAGGQDVYNDPD
                     LHYGLKSVYDGSRYIDNAGWYMDAVQPWSTFFVLPAVIALLGSYIICREEEEDTIKSL
                     RLIPINETKLTIAKMIITFIFSILLYLLLFTITFLTESVLHFSDLSTKLVLSCMKEYF
                     LDGIGVFFAISPIIALVSRMKKGYWLALVFTEVYSIAGLFAGMSNVLQTFFPIAAIFN
                     ISGYYITTGEKIMGSIISLLLCACLSAFILKGLKHNEKN"
BASE COUNT         5160 a         2818 c         2054 g         6169 t
ORIGIN      
        1 atatataaac aatcataata aaattttttt aataaaactt tattttttag ttaaaatcat
       61 acaatatata gatttccaca atacaaataa attaaaaagt gaaatgtatt tgtctaaaaa
      121 cataataaca tttcacttta tcctcatttt taagtaatat atatttttaa tttttattta
      181 taactaaatc tagtttttat ataaatttta gtttttttct acatctgagt aatctattcc
      241 aaaagtttct acagtaacag atttcataat ttgtggagtt tgtggcttgt cagctgaatc
      301 tgttctaact gatgctattt catcaactgt atccatacct tctatcactc taccaaagcc
      361 tgcatactga ccatctaagt gcggtgagtt tttatgcatt atgaaaaatt gagaaccagc
      421 tgaattaggt gccatagttc tagccattga tatgactcct ctttcatgtt ttaaattgtt
      481 agtaaatcca ttaccactaa attcaccttt tattgagtga cctggaccac ccattcctgt
      541 accatttggg catcctcctt gtatcataaa tcctggtatt actctatgaa atattattcc
      601 attgtaatat ccttcattta ctaatgatac aaagttttta actgtatttg gagctatatt
      661 tggatataac tcaattttga tttcttttcc attttccatt tctatagtta ctataggatt
      721 tttattttcc ataatttatt accttccttt tcattagtta aattacataa ttacatttat
      781 tatattatac tctaaattaa agtctatcaa gtatattttt tcctatttca tatccttctt
      841 gataaatagt tttacaaaac tcatcatcaa agttaagcgt gtctttagga gcaaattgag
      901 tattaggtct aactactatt attttatctt catcatatac ttttttaata tcttctggca
      961 actcataatt atattttgtg gatattaaaa taattttatc cacattatcc ccaattaatg
     1021 gttcaattaa tgcactccta attaaacctc catctaattt gaaaccatca taaattcctt
     1081 cttgcacatc tttcacaaat tgttctttaa atccaagagt tgcgtttgga tttgatggta
     1141 acaacccact gtatgaaatg ctgataatgg cttcattacg aggcattttt gatacgtcaa
     1201 caatcttttc tgatactact ttattatcaa cttcaacata attaacataa aagttcattt
     1261 cttctatatt actatcatct agttccctta ggttgtctat agcaggagaa ttatccacag
     1321 tattatttac tatttttaca tttccattct ggatatcttt tatatttgtc cacattttct
     1381 ccaagttatc aacattccct gtgtacaaat aatatccatt tattgctcct attgatgtcc
     1441 ctgaaatcga ataaaattta tttattcctc catcatacaa ggctttaact actcctgctt
     1501 gataagcccc ttttgctcct ccaccttcta aacataatcc taatttcata gtctcatctc
     1561 caaattgttt atcttatatt tatatttcaa aaaacttact aaatgtttta tatatactat
     1621 agtggtcctc aacgtttcct aattctctta tagagtgcat tgctaaaatt ggacttccca
     1681 catctacaga tggtatatct atatgagtag aagatattgg acctatggta cttcctcctc
     1741 tttcatctga cctattaaca aattcttgat actcaacatt agcttctcta catatatttt
     1801 tataaatagc tatagaatat ccatcactag tatatgcctg actagcattt atctttataa
     1861 ccggaccttt tcccattatt ggtttattag ttgggtcatg cttttctgga atgtttggat
     1921 gaatagcatg agctaaatct gatgatatca taaaagatga ataaatagac tcaaagaatc
     1981 cctctctatc cttacccatt gatatacaaa ttctctccaa tatatttaac aacatgtttg
     2041 aatctgcacc ttgtttagta gagctaccaa cttcttcatt gtcaaataca gccattacat
     2101 ttacaccatg ttgaccttta gtattaacaa gagcattcaa actagcatgt accattgcaa
     2161 gattatcttg tctcccaata gatataaatt catcattagc ccctattaaa cttccttttt
     2221 caaattcata taaaaataaa tcaaaatcta taatatcttc catatttaca tctaagttag
     2281 atgctatttg ctttataaga aaattatctt tttctaatgt atcatttaac atcccaacta
     2341 aaggtaacat atctttttgc ttattatatg aatgaccatc atttatactt ctatttaaat
     2401 gtattgctag atttggtatt atacaaattg gctttttaaa gtctataagc ctttcatttg
     2461 gttttaatat actatcacct tttaaaacta ctctaccagc tatcccaaga ggtctatcca
     2521 accatgtact taatattgct cctccatagc attctgtatt taacttcaaa taagattttt
     2581 cagcttctat ttctgcattt ggtttaatac taaatgtagg agaatctgaa tgagagccta
     2641 ttattctaaa tccatctctt tctatacctt ctgaatttac tacaaaagct actatagctg
     2701 ataaattctt agtaacataa tactttccac caactcttag attccatctt tgattcaaaa
     2761 ctaattcttc aaatccattt ttatctaaga tttccttagt actctcgact gcatgaaaag
     2821 acgacggact atcatatatg aagtctatta agtttttagc aaagtttata ctatccattc
     2881 ctcatttacc tccattataa aatatttagt gttgtatatt ctttatttat ttttttaatt
     2941 ccctgttggt caaaagctat agtaacatct gtaccaatta tagaaaccac tgtcccaacc
     3001 ccaaatttag gatgatgtac cttagaacca agttttatat catctggatt agtttcttta
     3061 ttagaatctt ttattgtagc attaacttta tctgcaactt tagatttgct tatagtactc
     3121 atatactttt tagtatattt atctaacata ttataacttg ctttagaata gcttagttct
     3181 ttttttactt tgtacaatct ttctatacat tcttctggca gttcttccat aaatcttgaa
     3241 gctattgcaa catttgtttt accatataat gttctcttct ctgtcaatga catatatagc
     3301 tcttctttag ctctagttat accaacataa caaagtcttc tctcttcttc tatttgtgaa
     3361 tcactcatag attttatagc tcttgatata ggaaataacc cttcttccat acctgttaaa
     3421 aacacaacag ggaattctaa acctttggat gtatgaattg tcataagcga aaccctatca
     3481 ttgtcttctt catcatttga ttcagatgta agtgctatac ttgttaggaa tgtctctaag
     3541 tctttatttt cataagtatc atcattacta ctttcaaact ccaaagctat agaaataaat
     3601 tctctcaaat tatcaattct gtcttgagct tcttcacctt tgcctgttaa atctttttca
     3661 tttttatttc ttatctctac aagctcgtcc atatatcctg tagtatccaa gactttttct
     3721 ataagtttgc taacaggata aacttctttt atagttctaa gagtccctat aatatcaaca
     3781 aatccactta tacttgccct tgccttagta gatatatctg aatttgtttc tatatcaatt
     3841 aatactgagt atatactttc ctgttttaag ttagctctat cttcaatttt ttctatagtt
     3901 ctaagcccta tacctcttct aggaacattt ataatccttt ttatagatat atcatcttgt
     3961 ggattttgaa taactcttaa atacgccaac aaatccttta tttcttttct ctcatagaat
     4021 tttgtaccac catatatatt gtatggaatt tgacttctat ttaaagcgtc ctctacaggt
     4081 cttgcctgtg catttgctct ataaagtact gcaaaatcct tataaggtct attttctttt
     4141 ctagctattt gtgcaattga atcagcaatg aaatcagcct cttctatttc gctaccagtt
     4201 aattgtatct ttataagttc tccttctttt ttttcactcc aaagcttttt tctttttctt
     4261 tctatattat tagatatgac tttattagct gcatctaata tcacttgtgt agacctataa
     4321 ttttgttcta actttacaac atgtacattg tcataatctt tctcaaattc aagtatgttt
     4381 cttatatctg cacctctcca tccataaata ctttggtcat catctccaac aacacaaata
     4441 ttttgatgtt ctcttgctaa taattttatc aattcatatt gagctttact tgtatcttgg
     4501 tactcatcta ccattatgta tctaaatcta cttctgtaat atgctaacac ttcatcatta
     4561 gccttgaaaa gttctacagt tttaagtatt aaatcatcaa agtcaagtgc actatttctt
     4621 tttaaacggt cttgatatag cgcataaata tctgcaatct taaccattct attatctgcc
     4681 atattgatat ctttaaactg ctttggagta taaagtttgt cttttgctcc tgaaattgca
     4741 cttataactg cttttggttc aaacacttta tcacttaaat ttaattcttt tagacagtct
     4801 ttaaccaatg taacttggtc tgctgaatca taaattacaa aacttctatt gtaaccaatc
     4861 ttatttatat cttttcttag tatacgaaca cagcaagaat ggaatgtact tatccacata
     4921 tccttagttt caggacctat attttgttca actctctctc tcatttcatt tgcagctttg
     4981 tttgtaaatg ttatagccaa tatatttggt gcttgtacac ctttatcttc tataagatat
     5041 gctattcttg ttgttaatac cttagtttta cctgaaccag caccagccag tataagtact
     5101 ggaccttcag tcttttctac tgcttctctt tgagcaggat ttaatgtatc taaattcata
     5161 tttctcctcc tgttaacagc cataaatata ttttaatcta aaatatgaat tacttcaaat
     5221 tataattatg tattatatta atagattatt tccaatatat tacaattaaa taacattttt
     5281 ccatataatt tatttcattg tttaataaaa aaaataacct tatgatttgg ggaatcataa
     5341 ggcaccttta aggggtctag gttaagggtt attatatata aatctatttt ttaaaaatag
     5401 gtttagggct taattattta tttgtattaa gttctctttc cttccaatac ttatacaaat
     5461 cttcttcttt cttaaataag ggtaaattca tatttctatg tacttttact aaccatgggg
     5521 attctagacc agcttgtata atattatttt catttataaa cacattttct gcctttcctt
     5581 catcaatcaa aatcccctta tccaatacat atatgtaatc acatatttca tacattaaat
     5641 tcatatcatg actggatatt actattttta tattattttt atttaatccc tttattatat
     5701 ctacaataga cctagtactt actgggtcta aaccagctgt aggttcatca agtaatacaa
     5761 tttcattttc cattgctata actgatgcta ttgccactct ttttttctgt ccatagctaa
     5821 gaaaatgtac tggcctgtct ataaaatcta ttccattaac agctactaga gctttgttta
     5881 ttctctcttt aattgttttt tcatccatac caatgtttct cattgcaaag gctatatcat
     5941 catatacttt tgaataaaaa atttgttttt ctgggtcttg gaacacaata cctacatttt
     6001 ttctaaggtt gtataaactt ctcttatcat attttaactt ttcttcttta aaaagaattt
     6061 ctccagatgt aggctttaat atacccatta aattcataaa taatgttgat tttcctgaac
     6121 catttgaacc tattatacct ataacatttc cctttgaaaa atccatatta atgtttaata
     6181 gtgcattggt atttttttca tattgatacg ttaaattatt tattttaaac atcattatcc
     6241 cctactatgt gaaatttacc atcatacaat tttatgtcta atgatataca catatcatca
     6301 taccttgtca taagtctttt gtacagcata cttccaagaa tacctaagga tttatatgaa
     6361 gtttttaaat ttatatatcc aaatcttagc tcttgtgact tgtatatttc tgaaaattct
     6421 tctaaaaata tgaatataaa cctatatatt aacattgata actcgacaaa agtgtcaggt
     6481 aaatgaagtt ttttaaaaaa gaatattaat tgattaaaag gtgttgtaag tatacaaaaa
     6541 tacacacaag tcaaacaaga catcgctcta aataacacat gaatagacat gtcaatagac
     6601 gcctttgata ttcctacatt aaaactaaaa aattcaaaac tatataataa atctgcttta
     6661 ttaaaagata tatttacaag agttattcct atactaagaa ataaaaagta cattggtatt
     6721 ctaagtaatt ttaaataatt ttttaaatct attccagcca cacaaacaac caaaatactc
     6781 attaaaatca taattccact taaaataaat atattttgta ttaccataga agcaatcaga
     6841 aaaattactc ctatggctac ttttttgttt ggatttactt tactcaatct atttgtatat
     6901 gcatatttat caattataag catgattaac ttctctttcc tttttgaaga cctaatatgt
     6961 atcctattac accagcccct aaagctgctt gtgcagagaa taataaactt tctatttctc
     7021 cacttggtgg ctcatatgga ctgctaaacc atggtttgta atttggattt atcttagtaa
     7081 tttcactttc agcttgacca tctgctcctc catattcagc acctgagttg acaagtaatg
     7141 ggaatataat aagagctact actaataaaa gtaataatat gttagttttt gtttttgttt
     7201 tagcactcat tagctttaac tcctttatca ttattttcta gtatgctttt ttctccattt
     7261 tctgtaatta aattatatac aattacagta agtatacctt ctgctattgc tattggtatt
     7321 tgagtcataa agaaaattcc taaaaactta attgctgaag ccatcactcc acctgatggg
     7381 tctgggaaag ccaatgctaa ttgtattgag gttattgtat atgtagccaa atctcctatt
     7441 gctgctgcaa gaaatactgg cattgcatta tttccgtctt ttttctttaa agccttaaat
     7501 attaggaatg atacgattgg ccctattatc gccattgaaa aagcattagc tcctaaagta
     7561 gttattcctc catgtgctaa caacaatgct tggaatatta aaactatagt tccaagaaca
     7621 aacattacgc ttggtccaaa cattattgct ccaagaccta caccagtagg atgtgaacaa
     7681 cttcctgtta ctgaaggtat ttttagtgct gataatacaa acacaaatgc tccacataaa
     7741 gctaataata ctttcttttt agggtcttgc tttactattt tacctattga ttttaatccg
     7801 aataagaaaa atggtataaa tataactccc catgctatag accattttac tggtaagtaa
     7861 ccttccatta tatgcattgc atttgatgta actggagtta aaatgattaa cataagtgca
     7921 gctataaccc ctaatttaat attctgtttc atcttagtat ccctctctcc ctttctaata
     7981 attaaaacat aataatacat gtctgattta tttaatcaaa taaaaaagcc taactcgatg
     8041 gttaggcttc taattttcca caatctaaat acaaacacat aaaacaaaca tatctgtata
     8101 attattataa gaaactttct ccatccccga agaaattact ttaatatttt aggcaggtct
     8161 cctgacttag cttcatccta ctcctcttcc ttcccatgag atataaaaaa tatcatcata
     8221 gtggctaaca aaagtttcgt ctgcatcaca gtagcggggg ctgtaaagga atttaacctt
     8281 tttccctatt aatcttgctt aaagaaccta taatattata tatttaattt ttaaattatt
     8341 cttaaatcat tttctatata aatcattgta tactttttct gtgaaaattt ctacattttt
     8401 tataaatttt attcattttt atatttttat gtatataaat tcttttttgt aagtttatta
     8461 atttctaatt atcttcttta aatacattga aactacatca gaaaatctag ttatatctct
     8521 tgaatatata aaatcatttc catatattaa tctttcagct tcaagttctg attcttttcc
     8581 tgtaaatact cctaatacta atatattttg ctttctagct tttctcactt cattggctgt
     8641 atctctcaaa ccaactatac ccctataagc cttttctcct cttaatgttc tctcactact
     8701 ttttcctatc tttacatcat ttggtcttcc atcgctgaga actatcagga ttttattttc
     8761 ttcatctcta tttattagac cactacatat agattttatt gccaaaccat ctctattatt
     8821 accagcacaa aaatattcaa atatattttc actatttttt atactatcat cataatcttt
     8881 aaatcttttt aatattgtat agtctaaaaa gctagaaaat cccatcactc tatttggtat
     8941 gccaacttct gttagagcat ttgcaattat gtaagcttga attgccacat ttccctgatt
     9001 tctactttga gagccacttg catccaataa tatatcaata acgtatttcc ctttttcatt
     9061 ttctatatct ttataaaata ttttattatt attacttcta ccaactctcc aagctctatt
     9121 tgctaatata gtaccacaat cagaatatac tctactttta gcattttctt ctattaaaat
     9181 tcttgataga ctttctttta atctctttat ttgctgtcta tacattctag catgttctct
     9241 aaattttcct aaattatttt ctttttgtct tgttacatat tttagttgaa atacattatt
     9301 acactcactt ctaagaactc catctgtaaa gtgtattcta caaccttcat gaacatttct
     9361 acaattttgt gtctcaattt ttttaatttc acctttactc aaataagttt ttccataata
     9421 atgttctatt tttgaatata tcttatttgc agtgtcttca tcaacatata taactcggtc
     9481 tgctgaattg ttacatttag aatcatcaaa atcccctaca ccttctacaa gcatggatga
     9541 agatattgaa tctatatcac tttcaataat attttcttct tcatcactat aaagttcttc
     9601 atacatgaaa tcagcaaatg tatcaaaatt tacttctaca ctttctacat tattttcatc
     9661 aataagacta ttttcttctc catttaatat gtattcaaaa taagttaaat atataacatc
     9721 taatgctttt aaaatctcca taatatcttg attggtatct atatttctta tatcattaac
     9781 tattcttcta gtcatactat ctaatgctgg gtgcttgtcc atactataaa gtacaaatgt
     9841 gtatttaatt ttatccataa tattatcatt gtgtattttg gtaaaacgtg aaacaatatc
     9901 tttataagca tttcttctta tgtcttctat ccccggccta tctttaatga ccttttcttc
     9961 aactattgta tttaatataa cttgaattag acccagtata atatctttgt tgtatccttt
    10021 tcttattcta tttgtaagat attttttaac tatatcccaa tctacatact ttcttctagc
    10081 acctgcaatt attgcaaaat atagacctat ttcttttgaa gagtaatctt tttctgatat
    10141 atctatactt tcattgtaat caccagctat tgtccatgat aagttattag ctctattttc
    10201 aaattcataa tcatcatata tccatttcat aatctcacct atattaaata tgacttattg
    10261 gaaacacatc tatactctcc catttattag gtattctagt tttaattaca tctccaacca
    10321 tttctttctc atatacatca aaagtctttc ctgtaagtcc catattaatt gcaagagttg
    10381 gttttaatcc tcttcttata gtcttaagag atgccataag accacgtaaa tcaatagctt
    10441 tactagatat ctctccattt tgagacttca attgtaaatc taaaaatatt cctgcaaagt
    10501 gtattaattt ttcttcatca gcatctgaaa attcattttt taaaatcatc attaacttat
    10561 cttcttctat aggaggaata tctattacca taaatctaga taccagtgct tcattaagtt
    10621 cttttgttcc tgcatattca taattcatag tcccaataaa tcttgttgct ggatgtagat
    10681 tgactctctc atacccaggt acatcaatta ttcttctata gtctaaagct gaatgtacca
    10741 caactatagc atcatttttt gccatattaa tttcatcaaa taccccaaaa cctccattaa
    10801 tagcacactc ataaactgag cctcttctaa gtttaacttc attgtctata aatgtatctg
    10861 tacctataag tgttgaactg tctgtattta tatgaaatga tgtattccac tgaggtctat
    10921 taaatatttc ccctagatta tcagcaagta agttttttcc cgttgccttt ggtcccgata
    10981 ataatatatt ttcttcttct aaaatagctg ctatacacat agacaagata tctttaccat
    11041 aaaaataagt tttagacttt gttactctgt attctaaatc tttttctaaa ccataataat
    11101 ttctaaaata cagtacatct tcaataagtt tttcatctac cccttgcacc cttagattat
    11161 ctattatatc catattttta ccccttttat ataaatagta tttgtttcat ttcttatcac
    11221 cattttagca taaaaggata taagctaaaa ttgatttttt aatctccccc attttaagta
    11281 aaaccatgca ccattttatc actacaaaat taagagtact acttactgat atttcttgat
    11341 tttgttcgtc tatacgtata taatatatgc tgataaatta tgaggaaagg atgattgaaa
    11401 tatggaatat atgtcttgcc cagaagtagc aaaaaaatgg ggtatttctg aaagaagagt
    11461 acaaaaacta tgtgaagaaa gtcgcatacc aggagtttca aaactcgggt atatgtggct
    11521 gataccaaag aacgcagaaa agcctgttga tggtagaaca aaaagaagaa aggaagtaca
    11581 atatgaatag cgttttgatt atagatgatg acaaagaact ttgtgctctt atgaaaaaat
    11641 gtgttgagca agaaaattta tctgctatta ctgcacattg tggtgcagaa ggtctacatt
    11701 tggtcgataa aaatagacac acactctctc ttgtaatttt ggacataatg atgccagata
    11761 tagacggttt tcaagttctg aaaaaaatta gagaaacaag taatattcca gtaattatgc
    11821 ttactgctaa aaatgacgag gatgataaag tttccggact acgtttaggt gctgacgatt
    11881 acctaacaaa accgttcagc ataaacgaac ttatggctcg tgtcaattct cttattcgtc
    11941 ggtatactat gttaaaccct gcttttataa cagacacaga ttgcataata ataaatggca
    12001 tgattattga caagacaaac cgaattgttt ctgtcaataa tattcctgtt caacttacaa
    12061 gcaaagaatt tgatttactt gcttttctgg cttctaataa gggacgggtg tttaccaaaa
    12121 aacagattta tacacaagta tgggaagaag aatatgcttt tgacgatagt aacatcatgt
    12181 ctttcatcag taaattgaga aaaaagattg aaccagaccc caaccatcca ttttatattt
    12241 tgacagttcg tggtgtcggt tatcgtttta ataaggaggc ttaacatgaa tacaagtgtc
    12301 tatctgcttt tgatattggc tcttagcctg attattatag cgtaccttgt ttctgtcctg
    12361 ctacgtgtcc gaatacaact tacacttata aaagatgctt tagaggatat aaaaaatgga
    12421 aaccttaatc gacgtatttt aacagatgaa aacgacatta caaaacaaat ttgctatgat
    12481 attaacgaaa tagcaatcaa tagccaattt caacttattc agcaaaaaca atcagaacaa
    12541 gcctacaaac agctaatgac aagtctctcc catgatgtaa aaactccact tgcttctttg
    12601 gtcggttatt tggaagcagt agaaagtaaa attgttgtag gagaggaaaa agacgagtat
    12661 atccatgttg cgtctaataa ggctcattac ttaaagaatt ttgtagaaaa tctatttgaa
    12721 tgggtaaaat tggattctaa ggaacaagtt tttcattttg atatttttga cttgaatgaa
    12781 ttatcccgta atattatatc tgattggata cctgttttag aaagcagtca ttttgaatat
    12841 gaatttgata taccagaaat agagtacttc ttacgtatag acgcaaatgc atatacccgt
    12901 atcattaata acctattaca aaatattatt acccatagta gtggcaacaa aatgacattg
    12961 agaatttttg aaaacaaaga gcaagctcaa attataataa cagataatgg gaaaggtata
    13021 tcttcagaca atctcccaca tatttttgaa aggttgtacc aatgcgacca ttcacgagct
    13081 tcaaagggaa atggtttagg cttggcgatt gcaaaggaac ttattaacgc tcataaggga
    13141 aatattaccg ccaacagcac tcccggtatg ggaacagaat ttacaatatt gcttcctaaa
    13201 gccctgtaaa agtacgaggc tttcttactc taaaacaaga taaaagcaag attatggcaa
    13261 ggttttggca aggttcatgt tttataattc taattgtagt tgattttgac gttgtatcaa
    13321 ctatcttttg tagaaacaaa tttattaaaa gtgaggaaat tatatatgaa tgattttgtg
    13381 attgaaacaa agcaacttac aaaaatttat gggaatcaaa cagtagttga caaagtcaat
    13441 ctccatgtaa aaaaaggccg aatatatggt ctgttaggac gcaacggggc tgggaaaacc
    13501 acaattatga aaatgatttt aggattgact tcaatcacgt atggcgaggt agatgtattt
    13561 ggagagaata ttaagggacg tgaaaaacaa gtatatcccc gtatcggcgc aattatcgaa
    13621 acgccaggat tttatcctaa tctgacagga acggagaact tggagatttt tgcaaaactg
    13681 cgtggtacag ccgcccctaa ttctgtaaaa agagcattgg agattgtagg cttaccttat
    13741 aaaaataaaa agctgtttag taaatattca cttggcatga aacagcgact tggtattgcc
    13801 aacgctatcc tgcatgaccc agaactgtta gttttagatg agccaaccaa tggtcttgac
    13861 cctattggta ttgcggagat gagaaagttt attagggact tgagcgttga gcatggaaag
    13921 acaattctta tttccagtca tattctttca gaaatctcat tgttggctga tgatattgga
    13981 attatcgacc acggtgttct tttggaagaa agtagtatga gtgaactaga aaagaaaaac
    14041 agtaaatata tcctgctaca agtttcagat attccgaaga catcacttat tttagagcgt
    14101 caatttaaca cgaaggatta ttccgttcaa gatgactaca cgttacacct ttataacact
    14161 aatctggata tgggtgaaat caataaagca cttgtaatgc agaatgtaat tgttattagt
    14221 tctcaacttt gtaatgatac tttagaggac tactttaaaa aaatcacagg aggagagggc
    14281 attgcttaaa cttattcaaa cagaatttct taaactgcgt cgtaggaaac ttatttggct
    14341 gatgttgttg tctgctctca ttatgccgtt tttcgcacta ctatacttca attattttgg
    14401 taaaacaggt gttgagccaa caaagtttta taaatggtct gcatttggtt atacactttg
    14461 gattattttg cccgttgttt tgggtatatt ttgcaccatg cttatacacg aagaaaacca
    14521 gtatgatatg ctcaaacagc tttggattgt acctattagt aaaatgggat acttttttag
    14581 taaatttttc gttgttttga tttactctat ttgttttatg ctgattacag ccgttgcttc
    14641 tgtgttattt agtgtacttt ctggatatgt cgtatttagc tgggcaagca ttttatattt
    14701 gttgaaaaaa tgtttagaaa ttggtgtaat cactgctttt gtaatgttgc cgattttggc
    14761 aatcgctaca tctcaaaaag gatacattct cccaatttgt atcacattgg tatatgcctt
    14821 ttccggtttt gttataatga caataaatat gtatttacac ccattatcca gtatgggagt
    14881 tattatcatg agaaataaag acattccagg tcttatattt tcacaggaaa ttaatgtccc
    14941 attagcattt ctttgtattt gtatttggag tattgtatca gtattgtttg caaacattgc
    15001 actaggaaga agaaagtgag gtgtagataa tgtggaaatt actttgggct gaatgtcaaa
    15061 aaattcgtcg ttcaaaaatt gtttggatta cagtttttgc atccattatg atagcagtca
    15121 tagtttttgc aggagggcag gatgtatata atgacccaga tttacattat ggcttaaaga
    15181 gcgtttatga cggttcacgg tatatagaca atgcaggttg gtatatggac gcagtacaac
    15241 cttggtcaac tttttttgtt cttcctgctg tcattgccct attaggaagc tatattattt
    15301 gtcgtgaaga agaggaggac actattaaat ccctgcgtct tattcccata aatgaaacaa
    15361 aattaaccat agcaaaaatg attattactt ttatattcag tatacttctt tatttgttac
    15421 tctttactat aacatttttg actgaatccg ttttacattt ttctgattta tcgacaaaac
    15481 tggttttaag ttgcatgaaa gagtattttc ttgatggcat aggtgtattc tttgcaattt
    15541 ctcccattat tgccttggta tcgcgcatga aaaaaggata ttggcttgca ttagtattca
    15601 cagaagttta ttctattgct ggactatttg cgggtatgtc aaatgtctta caaacctttt
    15661 ttcctattgc ggcaatattt aatatttctg gatactatat aactactgga gaaaaaatta
    15721 tggggagtat cataagttta ttactttgtg cctgcctttc tgcatttata cttaaagggc
    15781 taaaacacaa tgaaaaaaat tgaaataggt atatcaaaat gaaaaagata aaaaaactga
    15841 ttattctaat tgtattcttg tttctttttg gcatgttaca ctgttatact gaatggaaat
    15901 tcaacaataa cccacctaaa ggggtaatag aaagaataaa tgagtggact gataagattg
    15961 gactggatta gtaacttatg ttaattatag tgaatgtaat attagcaagt tattgtttcg
    16021 tattttaata ctataacttt aaatatttgg ttttaatctt ccaaacgaat ataaaaaaac
    16081 tgtcacagag gcaacatatt tttgaatatt tataaagtgg tagttttgat tttcaaagct
    16141 gccgcctttt cttctatata agcaaactta tcctcaacaa agtgtaaaac atggtacatt
    16201 t
//
LOCUS       DAEORM030000187        12243 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.guided.093, whole genome shotgun sequence.
ACCESSION   DAEORM030000187 DAEORM030000000
VERSION     DAEORM030000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12243)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12243)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 12243)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12243
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.guided.093"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            185..862
                     /locus_tag="KRH23_003932"
     CDS             185..862
                     /locus_tag="KRH23_003932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5227187.1"
                     /translation="MIVIEGSDKFKIAKEYIDVEYTLFSKVTFRYEKLKFKDNAELEK
                     IKMFKYKNGYIPNKLNLSFGYGFSSYKKQIIRETVDTLRLTEIFSSENIEDIKFIKDG
                     TKKLEISIEKVVKFKRRKKRNYVCCYCPDMYRDIKLDKESINKIYNRKIKIEREVNIF
                     EDEDVIINKKVLKFPKSWTKNMQKYWLSENKYPIHSTVIDDDRYKCCNVQYTKNRVII
                     LYYIYNH"
     gene            complement(1190..1957)
                     /gene="aroD"
                     /locus_tag="KRH23_003933"
     CDS             complement(1190..1957)
                     /gene="aroD"
                     /locus_tag="KRH23_003933"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003855 - 3-dehydroquinate dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HHS5227188.1"
                     /translation="MKRKVQVKNITIGEGRPKICVPIIGKNKKDIIKEAKELKDACLD
                     IIEWRVDFFENVENIKEVKEVLYELRSYIHDIPLLFTFRSVVEGGEKLISRDYYTTLN
                     KEISNTGLVDLIDVELFMGDEVIDEVVNFAHKKEVKVIISNHDFNKTPKKEEIVSRLC
                     RMQELGADLPKIAVMPQNEKDVLVLLEATNEMFKIYADRPIITMSMSGMGVISRLCGE
                     IFGSALTFGAAKSVSAPGQISFKELNSVLNLLHKSIN"
     gene            complement(2469..2618)
                     /locus_tag="KRH23_003934"
     CDS             complement(2469..2618)
                     /locus_tag="KRH23_003934"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5227189.1"
                     /translation="MTRVYYLFTTFDGILIRLNANLCKVSSKKKMSILLVDTGYIDIY
                     QLMKR"
     gene            complement(2629..3474)
                     /locus_tag="KRH23_003935"
                     /pseudo
     CDS             complement(2629..3474)
                     /locus_tag="KRH23_003935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009271880.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0009009 - site-specific recombinase
                     activity [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
     gene            3536..4650
                     /locus_tag="KRH23_003936"
                     /pseudo
     CDS             3536..4650
                     /locus_tag="KRH23_003936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898619.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
     gene            4669..4803
                     /locus_tag="KRH23_003937"
     CDS             4669..4803
                     /locus_tag="KRH23_003937"
                     /inference="COORDINATES: protein motif:HMM:NF024056.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5227190.1"
                     /translation="MKNYLTENLQQLNTEMVRSYIPTSSIVNSFPSLNLLCRKMTTGK
                     "
     gene            4902..5522
                     /locus_tag="KRH23_003938"
     CDS             4902..5522
                     /locus_tag="KRH23_003938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HHS5227191.1"
                     /translation="MHLIDFMNEDIKKKLVKKTYKKKETILFAEQENEYVILMIDGIA
                     EAFILNVKGNISTIHLYRSGSFFGEMEQFNDGKKPVEIVAFTDCNVYKLHRDDFLNWL
                     RGDFEATKFLIREISSKLVVNAELIEELSSLSVKERLLRCISLHYYRSELNLLTKKQL
                     ASEVNAPIRSINRAINECVQEHLIAYENKRFSVINQREVLKNLPTT"
     gene            complement(5746..5973)
                     /locus_tag="KRH23_003939"
     CDS             complement(5746..5973)
                     /locus_tag="KRH23_003939"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5227192.1"
                     /translation="MIVACNALTQLSYSWLATVFSNASIYWGASNSIFITPRGNLPKR
                     SCINGASTDCLKKDKKSIVSNSSLRPILVQA"
     gene            6201..7127
                     /locus_tag="KRH23_003940"
     CDS             6201..7127
                     /locus_tag="KRH23_003940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5227193.1"
                     /translation="MSDILSRITNKIGDKNIVDKLSALSKSDLNSLLLEVFDRQANTL
                     TATDILKSYQLNRFTIPSGIDPEEIHALESKLLRKAFNMDIKTIMLSPSAPLGSCSVF
                     GSVDQYNVVSALRGTETLADPSNMLAIIIADKLKRKEENNTIPIHMATTARVIRAQNF
                     VGKGLYSHFGLYCMVSSGIDTGSYTCEKMLLEKHLNYYKDILSEIENVRFSIILRKRN
                     GYKDNDGFFDRMVETIKLIFPNIELSIHNDDVDNNYYKGINFKISVKQGNETVEIADG
                     GFVDWTYQMLGNKKERCLISGIGLERFLVTVS"
     gene            7141..7590
                     /locus_tag="KRH23_003941"
     CDS             7141..7590
                     /locus_tag="KRH23_003941"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HHS5227194.1"
                     /translation="MELIEWNYAYITELVEFANDKEIANNLRDNFPHPYREQNARDFI
                     SFCLATPDVKQLSYAIFYQERAIGSISLTFEEDTSINKNAELGYWLARNYWGKGIATN
                     AVKEICKIAFEKYNLNKIHANVYSYNRGSSKVLEKCGFKIEEYCHNS"
     gene            8003..8356
                     /locus_tag="KRH23_003942"
     CDS             8003..8356
                     /locus_tag="KRH23_003942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HHS5227195.1"
                     /translation="MRNYARDIYDENKRRNDYLVSLESLSLAELSKLSILDDYDSNYI
                     CMVSYDYNIRIEDVLMAQAIGKLTKRKQDIILLSFFLNMTNADIATLMDLAENTIHYH
                     KTNALKELKELMQEH"
     gene            8358..8588
                     /locus_tag="KRH23_003943"
     CDS             8358..8588
                     /locus_tag="KRH23_003943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHS5227196.1"
                     /translation="MKPTKEVLPFTIILLAVHGDVNAINVILKHFEHYIIRLSQKTLF
                     DEYGNPYIHVEEETKRMLGTKLITAILRFNLS"
     gene            8963..9166
                     /locus_tag="KRH23_003944"
     CDS             8963..9166
                     /locus_tag="KRH23_003944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HHS5227197.1"
                     /translation="MNNTDVPIWEKYTLTIEEASKYFRIGEKKLRKLADENLDSGWVI
                     MNSNRIQIKRKQFEKIVDTLDFI"
     gene            9244..9594
                     /locus_tag="KRH23_003945"
                     /pseudo
     CDS             9244..9594
                     /locus_tag="KRH23_003945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009271880.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="integrase DNA-binding domain-containing protein"
     gene            9669..10301
                     /locus_tag="KRH23_003946"
     CDS             9669..10301
                     /locus_tag="KRH23_003946"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0046677 - response to antibiotic [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CatB-related O-acetyltransferase"
                     /protein_id="HHS5227198.1"
                     /translation="MTIPSSNKVYPRSNDYQTVYLKNVITRENIEVGDYTIYNDFYND
                     PRDFEKNNVLYHYPINNDKLIIGKFCSIACNAKFLMTSGNHSMKSKSTYTFPIFYEEW
                     KLDINHITDAWDNKGNIIIGNDVWIGYDSIIMSGVNIGDGAIIGTRAVVTNDVPPYSI
                     VGGVPAKIIKKRFNNDTISKLLEIKWWDWPYKKIQSNIKHIQSGNIDKLV"
     gene            complement(10672..11541)
                     /locus_tag="KRH23_003947"
     CDS             complement(10672..11541)
                     /locus_tag="KRH23_003947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HHS5227199.1"
                     /translation="MEYDMPLYRPPSEAYSLIIQVTLGCSHNKCTFCSMYKSKKFKIK
                     PLEVIKNEIDIFRRYYKHVERIFLADGDALIIPMEKLRDIIIYIKEVFPECERITMYG
                     SPKSIEKKSDDELKELRKLGVKMIYLGLESGSNEVLEDIKKGFSSEQLIKVGRKVKKS
                     GIKLSATVIAGLGGTKKTHQHAVDTGKMLGAISPDYVGVLSLMVEPNTELYDLLKAGE
                     FTILEDKAVLQEIKEMIKNIDANEKIVFRSNHASNYANLKGVLPDDKQRLIDEIDYYL
                     SNQKLKREEYRRL"
     gene            complement(11638..>12243)
                     /locus_tag="KRH23_003948"
     CDS             complement(11638..>12243)
                     /locus_tag="KRH23_003948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HHS5227200.1"
                     /translation="NSKVEVTVNENISFTPKGRKVSKGLILYPGAKVEIESYAPLARK
                     IAESGYEVVIVKMPLNLAILGTNKAQKVMDSYNNIEHWVIGGHSLGGVAASNFARDNK
                     LIEGVVFLASYPMGDELKELGKKVISIWGSKDGVVNFKSLVESKQKLPDDTTYVEIEG
                     GNHAQFGDYGKQKGDNDAIISQEKQLNITANSIIKFLKNIS"
BASE COUNT         4321 a         1848 c         1828 g         4246 t
ORIGIN      
        1 agattataga catcataaaa aagaataaaa tataattctt tatattttat ataaaaaaaa
       61 aggttatttg aaataaataa cctttttttg tctttttgtg ttaacattgt cttatagtgc
      121 taatgagtac tattagacca tgttctatgg ccttatttta atataaaacg attggagata
      181 ggctatgatt gtgattgaag gtagcgataa atttaagatt gcaaaagaat atattgatgt
      241 agaatatact ctttttagca aagtaacttt taggtatgaa aagttgaaat ttaaagataa
      301 tgctgaattg gaaaaaatta agatgtttaa atataaaaat ggctacatcc ctaataaatt
      361 aaacctttct tttggatatg gattctcttc ttataaaaag caaataatta gagaaactgt
      421 agatacttta agattgacag aaattttttc aagcgagaac atagaagata ttaaatttat
      481 aaaagatggt acaaaaaaat tagaaattag catagagaaa gttgtgaaat ttaaacgtcg
      541 aaaaaaaaga aattatgttt gttgctattg ccctgatatg tatagagaca taaaactcga
      601 caaagaatct atcaataaga tatacaacag aaaaataaaa atagaaagag aagttaatat
      661 ttttgaagat gaggatgtta taataaacaa aaaagtattg aagtttccaa agtcttggac
      721 aaagaatatg caaaaatatt ggttaagtga aaataagtat cccatacatt ctactgtaat
      781 tgatgatgat agatataaat gttgtaatgt acaatataca aaaaatagag tgataatatt
      841 atattacata tataaccatt aatatacata attacaaaaa aataatgaca aatatacata
      901 atacaaatat atcttctact ttagataaaa cagttattat aaaaacttac tatctataaa
      961 taatagaaat gctagtatac catctataat ctaatgtcta gtaggtttta atggcatatt
     1021 ttaaatatgc catagttgat ttataagatt ttctatatca ctttcaaaat acacactaaa
     1081 tagttgcttt tcagatataa ttgcccaatt taaattttac tatctgaaaa gttttttata
     1141 tttaatttat atcttcaaaa ataccgtcta atatttctat ataattaatt taattaatac
     1201 tcttatgtaa tagattaagt actgaattta actctttaaa tgatatttgc cctggtgctg
     1261 aaacactttt tgcagctcca aaagtcaatg cagaaccaaa tatttcacca cacaatctac
     1321 ttataacacc cattcctgac attgacattg ttattattgg tctatctgca taaattttaa
     1381 acatttcatt tgtagcttca agtagcacta acacatcttt ttcattttgc ggcataacag
     1441 ctattttagg taaatctgcg cccaattcct gcattctaca taaacgagat acaatctctt
     1501 ctttttttgg agttttatta aaatcatgat tagatataat tactttcact tcttttttat
     1561 gagcaaaatt aactacttca tctatgacct catctcccat aaataactct acatctatta
     1621 aatctactaa acctgtatta gaaatttctt tattcaaagt agtataataa tctcttgata
     1681 ttaatttttc tcccccttct actacacttc taaatgtgaa taataaaggg atatcatgta
     1741 tataacttct taattcatag agaacttcct taacttcttt aatattttct acattctcaa
     1801 aaaaatcaac tcgccactct ataatatcca aacatgcatc ttttaactct ttagcctctt
     1861 ttataatatc ttttttattt ttcccaataa ttggtacaca aattttaggt ctaccttctc
     1921 caatagtaat attttttact tgaacttttc ttttcatatt ctcctccata atcagaaatt
     1981 ttataggact ttaaattcta ttttctgcac aatttaatta tacattaaaa atactataca
     2041 ttataaaaat actaatttaa aaataatttt tattctaatt cttaaaacaa tcccacatat
     2101 tttagaaaag gtactctata atatacaaac acttcttttt tacctaaatt tattttaaca
     2161 tcctataatt ttcataatat tctttaaatt ttattcatat aaacaatatt attctggatg
     2221 ctaatagaat taatctataa atcatagtat aattatgcag aaataactcg aatttcacta
     2281 cttatgaaga gattgaatat taatgaatct aaatcatttg cattatttaa gagttttgac
     2341 taaagttgaa caccatacaa aagtagctac tcaattgttt ataccccaac caagcttaag
     2401 taatgttata tagattctcg aaaaagaatt tagtatcttt ttatttgaaa aacttatatt
     2461 aaatttgatt atcttttcat aagttggtaa atgtcgatat atcctgtatc tacaaggagt
     2521 atcgacattt tctttttgga agatactttg cataagttgg catttaaccg tataagaatg
     2581 ccatcaaaag tagtaaataa gtagtaaact ctagtcatac tactaggctt ataaccgttc
     2641 catttcagct ctcgcagaac taaatgaacc atgtgcataa tagccaagcg tcatagtaat
     2701 gtttttatgc cccataatat attgcaatat attagtactc attcctttgt tagccatatt
     2761 tgtacagagt gtatgcctaa aggtatgtgg cgtaatcttt ggtagcttgt cctcatgggt
     2821 cttgttatac ttcttgacta acgctcttaa catgctttga taatgagttg cttgttttgg
     2881 taatccatct tgtttaagaa ataggaagtt ctggtaacca tcaacaatga ttggttctgc
     2941 tttagcgttc ttacgccgtt caacgatacg ttcaaatgat tgataagctc tttcagtcat
     3001 tggaatttct cgcttaccct gtgtggtctt tggaacttct acataatagc caatcttagt
     3061 atcactcaac aattgatggt ctaccataat ggctttattt ttcatatcta attctaaagt
     3121 caaaccgcat aattcagaaa tgcgtagtcc tgtttctaat aggataacaa catcatcata
     3181 atatttacaa taagtcttat cgctctccat aaaggataat aagcccattt cctgttctgg
     3241 tgttagagcg atttttggtt ctgttgtatc ttccaaaaca tcacttaact gaaaattaaa
     3301 tggattcttt ctaatacagt catcttgaat tgccatgaaa aacgacgctt tcagtgagcg
     3361 cttataattg tcaatggatt tataagcaca cccatcttca ctcattcgga tagcccagct
     3421 tttagcgtct gataatttaa ccatatcaat gctttttgca cctagtgggt cattgatagt
     3481 atctatattt tgatttataa tttatacatt tttttaaaaa cagactttta actgtaaaga
     3541 atctatgtat aaacttagct atgttgtccg tgtatctaca aaggatcttg acgagctaaa
     3601 aaggcgttgt gatgaagtca aagactttta cgacgactta tcaatcaagc tcgtgcgtcc
     3661 ctttggggat atgttgggat tgcatggcga atttattcct gtcagcaaac gttacatcaa
     3721 tgattatatt caatatgtca cttcggattt tttggctgga cttggttttg gagcgacaca
     3781 aacccttggc gaacatgagg atatctatct tagctacaat ctggacactg gaaagaatgt
     3841 ctatctaaaa cctgcccttg ctagtcaagg ggtaaagggt tctattacca atgcgttagc
     3901 gtctgcgttt atcggttcat tgggtggtgg taaattattc agtaacaata tgcttgttta
     3961 ctatgcggta ctattcggcg gacaggcggt catagttgac cctaaagcag aacgcggcaa
     4021 atggaaagaa acgctaccag aaatagccca tgagataaac attgtcaatt taaccagtaa
     4081 tgatgaaaac aaaggattgc ttgaccctta cgtcattttg agccgtaaaa atgattctga
     4141 aagtttagcg attgatatcc taacattctt gctggtatct ccagtcgtga cagtgataag
     4201 ttcccagtgc ttagaaaagc aatccgcaat gtaacccaaa gtgaacagcg ggggttatta
     4261 cttgttattg atgaattacg aaaagaagat acttctatca gtaacagcat agccgaccat
     4321 atcgaaagtt ttgtagacta tgattttgca catctactgt ttagtgatgg aaatgtgaag
     4381 cagtctatca gcttggagaa acagctgaac attattcaag ttgctgacct cgtattgcca
     4441 gatgccgaca ctagttttga agaatataca acaatagaac ttcttagtgt tgctatgttg
     4501 attgttatta gtacctttgt attagacttt attcatactg accgctctat cttcaagata
     4561 gttgaccttg acgaagcatg gtcttttttg caggtggcac aaggtaaaac gctatctatg
     4621 aaactggtta gagcatcgca agattcacag gacaaacgaa ttgaacgttt gaagaattat
     4681 ctgactgaaa acctacaaca gttgaatact gaaatggttc gctcgtatat tcctactagt
     4741 tctattgtca acagctttcc cagtttgaac ttactttgca gaaaaatgac aactggaaaa
     4801 taataatgga atagtttcta tgtaaatata tttttattat cttacctaac taattgaaag
     4861 atgatataat ttaatcaaag atttggtaag gagggatgaa tatgcattta attgatttta
     4921 tgaatgaaga tattaaaaag aagcttgtta aaaaaacgta taaaaagaaa gagactattc
     4981 tttttgctga gcaagaaaat gaatatgtaa ttcttatgat tgatggtatt gcagaagcat
     5041 tcatcttaaa tgtgaaagga aacatctcaa ctattcatct ttatagaagt ggtagttttt
     5101 ttggagaaat ggaacaattt aatgatggga aaaaacccgt tgaaattgtc gctttcacag
     5161 attgtaatgt atataaactt catagagatg attttttaaa ctggttaagg ggcgattttg
     5221 aagctacaaa atttctgatt cgagaaatat ctagtaaatt agttgtaaat gctgaattaa
     5281 ttgaagaatt atcatcttta agtgttaaag aacgacttct gaggtgtata tccttacact
     5341 attatagaag tgaattaaat ctgcttacca aaaaacagct tgctagcgaa gtaaacgctc
     5401 caattagaag cattaatcgt gctataaatg aatgtgtaca agaacatcta attgcttatg
     5461 aaaacaaaag atttagtgta attaatcagc gagaggtatt aaagaatctt cctacaacat
     5521 aagtataatt tcaaaaaagt attggataat aattattcaa tactttttta tttcgggtca
     5581 agtgacctat ttttttttat ttcttcatta tataatactc ctatgcataa ttatgttgga
     5641 ttgatagcta ataaaagaaa gtgagaggtg ttatactaaa aaagaagcat acttcccaac
     5701 tccagactta cagtggattg aagatagatt ttggatttgg gttcattacg cttgcactaa
     5761 gattggacgt agagaactat ttgaaacaat tgatttttta tcttttttaa gacaatcagt
     5821 acttgcccca ttaatacagc ttctcttagg taaattacct cgtggagtta taaaaattga
     5881 attggacgca ccccaatata ttgaagcatt agaaaagacg gttgctaacc atgaatatga
     5941 aagctgtgtt aatgcattgc aggctactat caacctgtat cttgagttaa gagaggaatt
     6001 atcacaaagt cctattgtcc gaaaggttga agctgaaaga gttgcattac agtattttca
     6061 agatttaatc aaataaaccc aaagtaaaaa aatattgaat agtaaatatt cagtgttttt
     6121 tcatttttgg tcaaatgacc tagattagtt gttgtaacca ttctataatt attttgaaag
     6181 taacagtatg gaggataact atgagtgata ttttaagtag aattacaaat aaaattgggg
     6241 ataagaatat agttgataag ttatcagctc tatcaaaatc agatttgaac tcacttctat
     6301 tagaagtgtt tgatagacaa gcaaatactt taactgcaac tgatattcta aagtcatacc
     6361 aactaaatag atttactatc cctagcggta tagatccaga agaaattcac gctttggaat
     6421 caaaattatt gagaaaagca ttcaatatgg atatcaagac gattatgctt tctccctctg
     6481 ctccattagg tagctgtagc gtttttggct ccgtagatca atataacgta gtaagtgctc
     6541 tacgagggac agaaacactt gcagacccct caaatatgtt ggcaataatt attgctgata
     6601 aattaaaaag aaaagaagaa aataatacca tacctatcca catggctact actgctaggg
     6661 taataagagc acaaaatttt gtaggtaaag gtttatattc acattttggc ttatattgta
     6721 tggtttcatc tggtatagat acagggtctt acacttgtga aaaaatgttg ttagaaaagc
     6781 acttaaacta ttataaagat atattaagtg aaatagaaaa tgttcgtttc tctattattc
     6841 tacgcaaaag aaacggatac aaagataatg acggattttt cgacagaatg gttgaaacta
     6901 tcaaacttat ttttcctaat atagagttat caattcataa tgatgatgtt gataataatt
     6961 attataaagg tatcaatttc aaaatatcgg tcaaacaagg aaatgaaacc gttgaaatag
     7021 ctgacggtgg atttgttgac tggacttatc aaatgcttgg aaataaaaaa gaacgctgtt
     7081 tgataagtgg tattggctta gaaagatttc ttgtaactgt ttcataaaag gagaagaaaa
     7141 atggaactta tagagtggaa ttatgcttat attaccgagt tagttgagtt tgcgaatgat
     7201 aaagaaattg caaacaatct tcgtgacaac ttcccccacc cttataggga gcaaaacgct
     7261 agagatttta ttagtttttg tttggcaact ccagatgtta aacaacttag ctatgctatt
     7321 ttttatcaag aaagggctat tggaagtatc agcctaacat ttgaagaaga tacctctatt
     7381 aataaaaatg ctgaattagg ttactggctt gctaggaact attggggcaa agggatagca
     7441 acaaatgcag taaaagaaat atgcaaaatt gcctttgaaa aatacaacct taacaaaatt
     7501 catgctaatg tatattccta caatagaggg tcaagtaaag tattggaaaa atgtggtttt
     7561 aagattgaag aatactgtca caattcataa taaagaatag aaacatgatt gattgccatg
     7621 tatatagttt aattcgaccg caatagcatt tattagaatt aacctacttt ttaataacag
     7681 aataagtttt tcccctctat taatttctta tgcatctttg tatttttatg aaaagctagc
     7741 caatgcatat ttccatacat caatatggtg gtggcttaca accaatataa attaaatacg
     7801 ttttaaagaa tacacatttt tgccctatag gcagagtgtg tatttttttc tctttttttg
     7861 aaatttatcg aagatttaac gccctcccac cgtgatagga gtaagcaagg ttatttaact
     7921 ccttgcgatg gaaagagggt gaaatcttat ggttgatgaa aagacaattg aacatcaatt
     7981 cgacagtttc tgtaaaacag ttttgcgtaa ctatgctaga gatatttatg acgaaaataa
     8041 acgcagaaat gattatttgg tatctctcga atctttgtca cttgcagaat taagtaaatt
     8101 gagtatttta gatgattatg attctaacta catctgtatg gtttcttacg actacaacat
     8161 acgaattgaa gatgtattaa tggcgcaagc aatcggaaaa cttacaaaaa gaaaacaaga
     8221 tataattcta ctttcattct ttctcaacat gacaaatgct gacatagcaa cattgatgga
     8281 tttagcagaa aataccatac attatcacaa aacaaatgca ctaaaagagt tgaaagaact
     8341 catgcaggaa cattgaaatg aaacctacta aagaagtatt accttttaca attattttac
     8401 ttgctgtaca tggcgatgta aatgcaataa acgtaatact taaacatttt gaacactata
     8461 tcattcgtct ttcacagaaa actttatttg atgaatacgg aaatccctat attcatgtag
     8521 aagaagaaac aaagcgaatg ctaggaacaa aactaatcac tgctattttg agatttaatt
     8581 tgtcttaatc tcgccctctc tccatgtatc aagctatttg gtacatggag aatcactaat
     8641 tatttgtcta taaaagccca caagctattg tgatttttta taggcaaatc aatgccgact
     8701 gttctttgac aactgaataa agtagataga tacgtttgtg atacagatag ccaacaaata
     8761 ctatacgcca tgaccttaat caagagagcg actatataat gacctttgga acggttgttt
     8821 tgccgtaacc tgtaccacag tataatgata cacctgtatg acacgggccc ataagaatgg
     8881 gattggttga aataccagtg gagcttacca aagccatcta tctacttctg aactacgaac
     8941 atagaaagga atgatacatt ctatgaacaa tactgatgta cctatttggg aaaaatatac
     9001 cttgacgatt gaagaagcgt caaaatactt tcgtattgga gagaaaaaat tacgtaaact
     9061 tgctgatgaa aaccttgatt ctggctgggt cattatgaat agcaatcgca ttcaaataaa
     9121 gagaaaacaa tttgagaaaa tcgttgatac acttgacttt atctaatgaa attgagcctt
     9181 atatgttata atattcatat gacgtatcaa gctcaattcg gttattgaga ggagcttctt
     9241 atcatgtcaa ctgaaaaaag acgagataat aaagatagaa ttttaagaac tggagagagc
     9301 cagagaaaag atggaagata cgcatataag tatgtatatt catttggtaa accacaattt
     9361 gtttactctt ggaaacttgt acctactgat aaacccccaa agggaaaacg tgatgatata
     9421 tcattaaggg ataaggaaaa agcaatacaa aatgaccttg atgatagcat tgacactatt
     9481 ggtaagaaaa tgacagtttg tcagttatac gctaaaaaga atggactaag aaagaatatc
     9541 cgacttaaca ctaaaaaagg acgccattat cttatgaaga ttcttaacaa ggagtgattc
     9601 tgtgaagaga tgtattgtag tagtggaata gtcaaaaaca taatatatat taaaggagag
     9661 atttaaatat gactattcca agttcaaata aggtatatcc aagaagtaat gattatcaaa
     9721 ctgtatatct taaaaatgta ataacaaggg aaaatataga agttggagat tacacaatat
     9781 ataatgactt ttataatgac ccaagagatt ttgagaaaaa caatgtattg tatcattacc
     9841 ctataaacaa tgataaatta ataattggta agttttgctc aatagcatgt aatgcaaaat
     9901 ttctaatgac tagtggaaat cactcaatga aatcaaaatc cacatatact tttcccatct
     9961 tttatgaaga atggaaactc gatatcaacc atataacgga cgcttgggac aataagggta
    10021 acattataat tggaaatgat gtgtggatag gttatgattc tataattatg tcaggtgtaa
    10081 atattggtga tggtgcaatt attggaacaa gagcagtagt tactaatgac gttccaccgt
    10141 attctattgt tggaggagta cctgcaaaaa ttataaaaaa gagatttaat aatgatacaa
    10201 tttcaaaatt attagaaatt aaatggtggg attggccata taaaaaaatt caatcaaaca
    10261 ttaagcatat tcaatcagga aatattgata aattagttta atattttata atttatttat
    10321 attaaacttt actttaataa tcattttata agagcttttt caaaatttgt atattatttt
    10381 aatatatata aatttaatac aacattaaat aaaataaaaa gtaaagttac ttaataaaaa
    10441 gttactttac tttttattgt ttaaattcct gtttttatta taataggtaa aattctatta
    10501 aactagttca cattttcatt attattgata tattatatat gaatatacca ttttgttttt
    10561 taataaaaaa atcatgctac atcaatagta agcaactatt aatgtagcat gattttttgt
    10621 atctaaataa tcttagtatt tacctatcaa tatagattga tatatcaaaa actatagtct
    10681 tctatattct tctcttttta gcttttgatt acttagatag taatcaattt catcaattag
    10741 acgttgttta tcatcaggta atacaccttt taaattagca taatttgatg catgattact
    10801 tctaaataca attttttcat tagcatctat attctttatc atctctttaa tttcttgtaa
    10861 cacagcctta tcctctagta ttgtaaactc tcctgcctta agtaaatcgt aaagttcagt
    10921 attaggttct accattaaac taagtacacc cacataatct ggtgaaattg ctcctaacat
    10981 ttttcctgta tcaactgcat gctgatgtgt ttttttagtt cctccaagac ctgctattac
    11041 agtggctgat aatttaatcc cacttttttt aacttttcta ccaactttta ttaattgttc
    11101 actactaaaa cctttcttaa tatcttctaa tacttcattg cttccacttt caagccctag
    11161 ataaatcatt ttaacaccaa gttttcttaa ttctttaagt tcatcatcag attttttctc
    11221 tatagattta ggagagccgt acatagtaat tctttcacac tctggaaaaa cttcttttat
    11281 atatataata atatctctta atttctccat tggtattatc aatgcatctc catctgctaa
    11341 gaatattctt tctacatgct tataatatct tctaaatata tcaatttcat tttttattac
    11401 ttctagtggc tttattttaa attttttaga tttgtacata ctacaaaacg tacatttgtt
    11461 atgagaacat cctagtgtga cttgtattat aagactataa gcctcacttg gtggtctgta
    11521 aagtggcata tcgtattcca tattaaaatc ccccttgtaa taaaatattc attctattat
    11581 attattaata tttactttaa ataataactt ataaaattat attttttaaa ttttagttta
    11641 agatatattc tttaaaaatt taatgatact attggcagta atattaagtt gtttttcttg
    11701 acttataata gcatcattat ctcccttttg ttttccataa tctccaaatt gtgcatgatt
    11761 tcctccttca atctcaacat aagttgtatc atcaggaagt ttttgttttg attctacaag
    11821 acttttaaaa ttgactactc catctttgct cccccatata gatataactt tttttcctaa
    11881 ttctttcaac tcatcaccca ttggataaga agctaaaaat acaacgcctt caattaattt
    11941 attatcacgt gcaaaatttg atgctgcaac tcctcctaat gaatgacctc ctattaccca
    12001 atgttctatg ttgttgtaag aatccataac tttctgtgcc ttattagttc caagtatagc
    12061 tagattaagt ggcatcttta cgattacaac ctcatatcca ctttctgcta tttttcttgc
    12121 aagtggagca taagattcta tttctacttt agctcctgga tacaaaatta aacctttaga
    12181 aacttttctt ccttttggtg taaatgaaat gttttcattt acagttactt caactttact
    12241 att
//
LOCUS       DAEORM030000188        11915 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.guided.094, whole genome shotgun sequence.
ACCESSION   DAEORM030000188 DAEORM030000000
VERSION     DAEORM030000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11915)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11915)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 11915)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11915
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.guided.094"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            complement(116..808)
                     /locus_tag="KRH23_003949"
     CDS             complement(116..808)
                     /locus_tag="KRH23_003949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FadR/GntR family transcriptional regulator"
                     /protein_id="HHS5227201.1"
                     /translation="MKSLNATEKIIDYIKLNILNGTFKINSKLPSERKIADLFNISRI
                     PVRNAINILCKEGILRAVPYSSPIVEGFKKVDLFDDGEIYKNHNIQEFYVESLRARQL
                     IESEATKLAILNATSKELQKIKYTYLKSIDELDKVSHGLIEECYDADLQFHKEIILAS
                     HNPIFIKYYELIPKTVSSNQYFGFKYRNSLKDMISHHNKIMIAFDSKDSYLGYTSMYN
                     HLEDVIQLFQHD"
     gene            complement(834..2021)
                     /locus_tag="KRH23_003950"
     CDS             complement(834..2021)
                     /locus_tag="KRH23_003950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HHS5227202.1"
                     /translation="MKKISNQKLLLLSIVTFFWFSQYVYIPFQNPYLSACNVSTNMIG
                     IIIGAYGISQCLLRLPVGVFADSINKHKIFILSGIFFAGLASLIRVFSPGGNGFLIAN
                     ILSGISSSTWISYMVHYTNFFSTEHQQKATSTIILVNNLGMLIGFVMSTLFYEKLGMT
                     ALCIMSVLSSVIGTILALNIKNHNSKKIPEKISIKKYLSICKDKRLVFFSFMALIQQG
                     IQMSTTMSFTTQILKNLGSSSTLIGLSSIFYMVCAVASSGFASTKFCTKYGPKFWIPL
                     VFILVSAYCFLVPTIKNINIIFVLQVLPGISTGILLSYLTSESMKNVPKHQKSTAMGF
                     FQAIYAIGMSVFPMIVGKISEYTSIQYGYFILAIIAILASILSYTYYKKVDLTLNYDI
                     IQS"
     gene            2357..4234
                     /locus_tag="KRH23_003951"
     CDS             2357..4234
                     /locus_tag="KRH23_003951"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HHS5227203.1"
                     /translation="MDYKNIAQEILLNVGGKENVNEVTHCMTRLRFKVKSASKVNKDK
                     LSKTEGVITVVESMGQIQVVIGNKVKKVYDEVIKIVPQSNNVGKKNESQEKQGIINSI
                     LSAVAGIFTPTIPAIAGVGMIKGILSVLAMYYMNKNGVDIKETQSYIILNAMADSIFY
                     FMPIILGYTAAKVFNANKIISMVLGATLCYPTFTALMAGEESVRFLGLAVTKATYTSS
                     VIPIIIAIWALSYVEKVLEKYIPEVIKIIMVPTLSLVVMLPATLFLFGPIGIYIGNVI
                     NFSYKYIYELSPALCGAFVGGLWCVLVIFGAHRALLPIGISDVAQTGRQNLLAFAGAA
                     NFSQAGAALGVFFKTKNQGLKTISMSATITALFGITEPAIYGANLRLKKPMVCAVICG
                     AFGGAIMGMGGAYGNAFANQGVLTIPVYAEAGALGFLSYLGGCAIAFFGSAISTYLVG
                     FEDLEESSNKENSSIKVETKDGVIDITSPVEGECIELSEVKDDVFASKAMGEGIAVLP
                     TKGVITAPTDCEVASLFPTLHAIGLKLDNGAEMLIHVGINTVELNGKYFTKHVNQGDL
                     VKKGDKLISFDIDKIKKAGYDVTTPVIVNNTFDFGQVVSCKSSYVSTNDNIISLVLAG
                     N"
     gene            4456..5862
                     /locus_tag="KRH23_003952"
     CDS             4456..5862
                     /locus_tag="KRH23_003952"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HHS5227204.1"
                     /translation="MNTGFPKDFLWGASSSAFQVEGAWDKDNKGKTVADYNSFKKSHL
                     QADTKVASDFYHNYEEDIELMKELGMKTYRFSISWARIIPDGEGEINQKGLDFYNKII
                     DKLIECDIEPFVTLYHFDLPFKLVEKYNGWESRETVYAFERFAKICFKHFGDRVKYWQ
                     PHNEQNLIVRVEERINIYDETDSWKIDKMRAQMDYNLCLAHALAVNACHEMIKESKIG
                     AAVSSSVTYPLTSKPEDVYAARMNDNFKVYYMLDMHHYGEYPGYYMKYLEKRNIVPHM
                     EDGDKEILKKAKMDFIAVNYYRTNCAEALPEDSQHPFGLREGTVDFSMYGLFKMSMNP
                     NLEASEYGAAIDPSGLRVALNEYWQRYHLPVIITENGLGAKDILEDGKIHDDYRIDYL
                     RSHINACKLAIEDGVEMIGYCPWSFTDLLSSSQGFNKRYGLVYINRTDHEVLDLKRIK
                     KDSFYWYKEVIENNGIVK"
     gene            5890..6738
                     /locus_tag="KRH23_003953"
     CDS             5890..6738
                     /locus_tag="KRH23_003953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HHS5227205.1"
                     /translation="MYITKVLNNSLLLAKDDNDEEIILMGKGIGHNYKAGSELNKKDI
                     EKIFVLHDENIKKSIIQLATEIDAEYFGIAQMIIAYGIEKYNLKLMNHIYLALTDHIA
                     FAVRRFKEGIMIENHYLFEIKEFNPKEYDIGKYAITVFKEVLGLDLPEEEIGNIAGHF
                     INAQQDNPYSDRNKRSAKIVNAILQIVHYHFSIVYNKESFYYRRFVMHLKAFSQRFLA
                     NEPSREKIDFIYEQVQKNCKEEYECVKKVGAYMYKEYSRELPRQEELYLMIHIHKILG
                     ELCENS"
     gene            7410..8102
                     /locus_tag="KRH23_003954"
     CDS             7410..8102
                     /locus_tag="KRH23_003954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HHS5227206.1"
                     /translation="MNKVLIIDDDKDLCILLKKSISIEQIEANYCHSGRDGLVELSKQ
                     DYQLVVLDVMMPGMDGFETMEQIRKYSSIPILMLTSKSDNYSKVHGLRAGADDYLTKP
                     FEITEFTARVLSLIRRYTRFNPKNEEPQQLSFKGLLIDLDQHTVTTNGEPMLLPPKEF
                     GVLLYCARHQGKILTKQQIYEAVWGEPYVYDDSNIMAIISRLRKKIELDPSSPIYLQT
                     IKGIGYQFNTEV"
     gene            8099..9034
                     /locus_tag="KRH23_003955"
     CDS             8099..9034
                     /locus_tag="KRH23_003955"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HHS5227207.1"
                     /translation="MKMDEQTIILFLLLLSIGLLFLSIFAFSKLGHIYKRLKDIEEIL
                     ADVRIGDENRKILIKPCDVMAPLVYQLNEIVYDYENKLLSLKKSDKASRQLMTSLSHD
                     VRTPLTTLIGYLDAVHSGIVIEQEREEYLEIARRRAYDLKDYIDVLFDWFRLNSDEFT
                     LSIESVEIAELSRNILKDWIPIFHEKKLNFEIDIPENRLMVNLDPDGYSRVVNNLVQN
                     VLAHSKARQIKITMSEDSRMVLLRVEDDGVGIARENLPHIFERLYKCDKGRSEKGSGL
                     GLSIVSQMVERMGGQISVESEIGKYTIFTVSLPLI"
     gene            9182..10105
                     /locus_tag="KRH23_003956"
     CDS             9182..10105
                     /locus_tag="KRH23_003956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019639192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHS5227208.1"
                     /translation="MNNLIIETKNLTKQYGAQKSVSNLNIHVQKGRIYGLLGRNGAGK
                     TTTMKMLLGLTKPTTGEIKIFGQDIHNNEKKLLPRIGCLIESPGFYPNLTGTENLKIF
                     ARLRGIPKKNAVESALDVVGLPNNDKKLFSQYSLGMKQRLAIALAIMHDPQLLILDEP
                     INGLDPIGIAEVRTFIRDLCTERGKTILISSHILSEIALLADDIGIIDHGILLEEESL
                     AQLEEKNSKYIHFAVSDAAQAARLLETQLNLKNFKVADNYNIMLYDTDVSVAEINRAF
                     ILNNIEVSESHLCEDTLEDYFKKVTGGEGIA"
     gene            10089..10859
                     /locus_tag="KRH23_003957"
     CDS             10089..10859
                     /locus_tag="KRH23_003957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHS5227209.1"
                     /translation="MKELLDIISCEFSKLKRLKFILISILGACLFPIPATILIAKDNL
                     PFEQLFKLVVNFGYFLLLPIVLSIVASQLFFIERDNDVLKNLATVPVPKGKLALAKLA
                     VLLFISLFYSVAGLGATIIGGFIVGIVEGVAVKLGMSIAFGIMFFVTVLPVVVLIVYF
                     NRSYIFSIILSFVYAIFNFSISLNIINFEPNNPLLSVLPAPVIMRWWMAFWGDPTGEY
                     TVLRQPYLLSTPACVGILCLITIIAVLLICMIYKKQEN"
     gene            10869..11651
                     /locus_tag="KRH23_003958"
     CDS             10869..11651
                     /locus_tag="KRH23_003958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHS5227210.1"
                     /translation="MLDIITTEFQKIKRYNILWIGVVAVLFSALLAVFQVVSSHGSDP
                     LTYESFANGVIWNNFSLSFPFGITLIGGYLINREYTDQTLKNILTVPISLRKLLVGKL
                     IAVGGITVLLSLFSFLCTFILGLLFCNINISVILVVKSLVQILSVNLYCYVAVLPIIA
                     YFGRKQNAFLTGVGIAFVYGFCGVFVAGRNLTDFYPITAGLGLVGYNNGAGTVYQPLI
                     GAMTLIVILILTTILLVFTPNYDKVMTISKKKGIKHKKYSHK"
BASE COUNT         4187 a         1570 c         2150 g         4008 t
ORIGIN      
        1 tgaaatgatg aaaatatatt tgatttcata caaaaaagag tacctcataa ctaaaaagtt
       61 cactttgaga cactccattt ttatatgtta gttgcattta aggtaaaata taagtttaat
      121 catgttgaaa taactgaatt acatcttcta aatgattgta cattgatgta taacctaagt
      181 aagagtcttt actatcaaat gcaatcatta tcttgttatg gtggctaatc atatccttga
      241 gagaatttct atatttaaaa ccgaagtatt ggttagaaga aactgtttta ggtattaact
      301 cataatattt tataaaaatt ggattatgag aagctaaaat tatctctttg tgaaattgca
      361 agtcagcatc ataacattct tctatcaaac catgagaaac cttatccaat tcatctattg
      421 actttaggta agtatatttt attttttgaa gttctttaga tgtagcattt aaaattgcta
      481 gtttagtagc ttcgctttcg ataagttgtc ttgctcttaa agattctaca taaaattctt
      541 gtatgttatg atttttatag atttcaccat catcaaatag gtcaactttt ttaaatcctt
      601 caactatagg acttgaataa ggcacagctc taagtattcc ttccttacag agtatattta
      661 tggcatttct tacaggtatt ctacttatgt taaataggtc agcaatcttt ctctcacttg
      721 gtaatttact attaatttta aacgttccat ttagaatgtt taatttaata taatcaataa
      781 ttttttcagt ggcatttaag cttttcataa aaactcctaa acatataatt tttttatgat
      841 tgtattatat catagttaag agttaaatct acttttttat aatatgtata agacaggata
      901 gaggccaaaa tagctataat agccaagata aagtatccat attgtattga agtatattcc
      961 gatattttac caactatcat tggaaataca gacattccta tagcataaat tgcttgaaaa
     1021 aaacccattg cagtagattt ctgatgtttt ggtacatttt tcatagactc gctagtaagg
     1081 taagaaagga gtatacctgt agatatacct ggtagtactt gtagtacaaa tattatatta
     1141 atatttttta ttgttggaac taaaaagcaa taggctgaaa ctaaaataaa aactaaagga
     1201 atccaaaatt ttggtccata cttagtacaa aatttagtag aagcaaagcc agaagaagca
     1261 acagcacaca ccatgtaaaa tatagaagat agacctatga gggtagaact agaacctaag
     1321 tttttaagaa tttgagtagt aaatgacatt gttgtagaca tttgaatacc ctgttgaatt
     1381 aatgccataa aggaaaaaaa tacaagtctt ttatccttgc agatagataa atatttttta
     1441 attgatattt tttcaggtat tttttttgaa ttatgatttt ttatatttaa ggctagaatc
     1501 gttccaataa ctgaagacaa tacactcatg atacataagg ctgtcattcc taatttttca
     1561 taaaataaag tactcataac aaatccaatc aacattccta gattgtttac caatattatc
     1621 gtacttgtag ctttttgttg atgttctgta gaaaaaaagt tggtatagtg aaccatgtaa
     1681 gaaatccaag ttgatgatga tattccagat aaaatgttag ctataagaaa accattgcct
     1741 ccaggagaaa agactcttat aagagatgct aaaccagcaa agaaaattcc agacagtata
     1801 aatattttat gtttatttat agaatcagca aatactccaa caggaagcct taataaacat
     1861 tgtgatattc catatgcacc tattattata ccaatcatat ttgtagatac attacatgca
     1921 cttaaatatg gattttggaa aggtatatat acatattgtg aaaaccagaa aaatgtaaca
     1981 atagaaagta aaagtaattt ttgattagat atttttttca tattatcctc catatggtat
     2041 ttttataatg caaataatat accatttaga ttttttaatc aagtacttta tctattaaaa
     2101 aaaatttaaa tatataatta ttatttacaa aaaaattata ctttatagtt gaattaagaa
     2161 aacgcttatg atactataaa gttaacaaat ttgaatatat aacagtagac gtgttactgg
     2221 taatgcaggc aagatcgaat caatttttat agattatcta tagagtacta tgggtataat
     2281 ctatttattt ggttcgattt ttttgtttaa ttggccataa aacaaaaagc ctatagttga
     2341 aaatggagga ttttttatgg attataaaaa tatagctcaa gaaattctac taaatgtagg
     2401 aggaaaagag aatgtaaatg aagtgactca ttgtatgaca agacttagat ttaaagtcaa
     2461 aagcgcttct aaagtgaata aggataaatt atctaaaact gaaggagtaa taactgttgt
     2521 tgagagtatg ggtcaaatac aagttgtaat tggaaataaa gtaaaaaaag tatatgatga
     2581 ggttataaaa attgtacctc aatcaaataa cgtaggtaaa aagaatgaaa gtcaagaaaa
     2641 gcaaggtata attaattcta tattatcagc agtagctggt atatttacac ctacaatacc
     2701 tgctatagca ggggttggta tgattaaagg tattttatca gttcttgcta tgtattatat
     2761 gaataaaaat ggagtagata taaaagaaac gcaaagctat attatcttaa atgctatggc
     2821 tgattctata ttctatttta tgcctattat actaggatat actgcggcta aagtatttaa
     2881 tgcaaataaa ataatatcta tggtattagg agctacactt tgttatccaa cttttactgc
     2941 tttgatggca ggtgaagaat ctgttagatt tttaggattg gcagtaacaa aagctacgta
     3001 tacatcatct gttattccaa taattattgc tatatgggct ctttcatacg ttgaaaaagt
     3061 attagaaaag tatatacctg aggtaattaa aataataatg gttccaactt tatcattggt
     3121 tgtaatgtta cctgcaacat tatttttatt tggaccaatc ggaatttata taggaaatgt
     3181 cataaacttt tcttataagt atatttatga attaagccca gcattgtgtg gagcatttgt
     3241 aggtgggtta tggtgtgtgt tggttatatt tggtgctcat agagcattat taccaatagg
     3301 tataagtgat gttgctcaaa caggaagaca gaatttattg gcgtttgcag gagctgcaaa
     3361 cttttcacaa gcaggggctg ctctaggagt attctttaaa actaaaaatc aaggactaaa
     3421 aacaatttct atgtctgcaa ctataacagc tttatttggt ataactgaac ctgcaatata
     3481 cggtgccaat cttagattaa aaaaacctat ggtatgtgcc gtaatatgtg gtgcatttgg
     3541 aggtgcgata atgggaatgg gtggagctta tggtaatgca tttgcaaacc aaggtgtttt
     3601 aactatacct gtatatgctg aagcaggtgc attaggtttc ttaagttatc taggtggttg
     3661 tgctatagca ttttttggtt cagctatttc aacttatcta gttggatttg aagatttgga
     3721 agagtcttct aataaggaaa attcatctat aaaagtagaa acgaaggatg gtgttattga
     3781 tataacttca cctgtagagg gcgaatgtat agaattgtca gaagtaaagg atgatgtatt
     3841 tgcttcaaaa gctatgggag aaggtatagc tgtgttacct acaaaaggag taataacagc
     3901 ccctactgat tgtgaagtag cttctttatt tccaacatta catgcaatag gattaaaatt
     3961 agataatgga gcagaaatgt taatacatgt tggaatcaat acagtagagt taaatggtaa
     4021 atactttacc aaacatgtta atcaaggaga tttagtgaaa aaaggtgata aacttatatc
     4081 gtttgatata gataaaataa aaaaggctgg ttatgatgta actacgccag ttatagtaaa
     4141 caatacattt gattttggac aagtggtttc ttgtaaatct agttatgttt caaccaatga
     4201 taatataatt tcattagtat tagctggtaa ttaagttaat ttgactagag ataagtaaat
     4261 tgatttaaaa ggaaataagt aaatcaacaa ttaaatacat ctaaaagtaa gtttattgca
     4321 atgaattgtt aaagaaaata attaatatag ggtaaatcta tctcaatgaa ataacaaaga
     4381 aaagagttaa tatagagtga acttattgca atgaatcaac aaagaaaata atcaatataa
     4441 aaaggagaaa tatttatgaa tacaggattt ccaaaagact ttttatgggg agcatcatct
     4501 tctgcatttc aagtggaagg agcttgggat aaagacaata aaggaaaaac cgtagccgac
     4561 tataattctt ttaaaaagtc tcatttacag gcagatacta aagtcgcatc agacttttac
     4621 cataattatg aagaagatat tgaattaatg aaagaattag ggatgaaaac atatcgtttt
     4681 tcaatttcat gggcaagaat aataccagat ggtgaaggag agataaacca gaaaggttta
     4741 gacttttata ataagataat agacaaacta atagagtgtg atattgagcc attcgtaact
     4801 ttataccatt ttgaccttcc atttaaatta gtagagaaat ataatggttg ggaaagtaga
     4861 gaaactgtct atgcttttga aagatttgct aaaatatgct ttaagcattt tggagatagg
     4921 gtaaagtatt ggcaacctca taatgaacag aatttaattg ttagagtgga ggagagaatt
     4981 aatatatatg atgaaacaga ttcatggaag atagataaaa tgcgtgctca gatggattat
     5041 aatctttgct tagcacatgc attagcagtc aatgcatgtc atgagatgat aaaagaaagt
     5101 aaaattggag cagcagtatc atcatctgta acatatcctc ttacttctaa gccagaagat
     5161 gtatatgcag ctagaatgaa tgataatttt aaagtgtact atatgcttga tatgcatcat
     5221 tatggagaat atccagggta ttatatgaag tatcttgaaa aaagaaatat agttcctcac
     5281 atggaagatg gggataaaga gatacttaaa aaagctaaaa tggattttat agctgtaaat
     5341 tattatagga caaattgtgc agaagcttta cctgaagatt cacaacatcc atttggatta
     5401 agagaaggaa ctgttgattt tagtatgtat ggactattta aaatgtcaat gaatcctaac
     5461 ttagaggctt ctgagtatgg agcagcaata gacccatcag gtcttagagt tgccttaaat
     5521 gaatattggc aaagatatca cttacctgtt ataataacag aaaatggtct aggagctaaa
     5581 gatatattag aagatggaaa aattcatgat gactatcgta tagactattt aagaagtcat
     5641 ataaatgcat gtaaactagc tattgaagat ggtgtagaga tgattggata ttgtccatgg
     5701 tcatttacag accttttaag ttcttctcaa ggctttaata agcgttatgg acttgtttat
     5761 ataaatagaa ctgaccatga agttttagat ttaaaaagaa tcaagaaaga tagtttttac
     5821 tggtataaag aagttataga gaacaatgga atagtaaaat aaacataaat atatattgag
     5881 ggttttagta tgtacattac aaaggtatta aataattcgt tgctacttgc aaaggatgat
     5941 aatgatgaag aaataatatt gatggggaaa ggcattggcc ataattataa ggccgggtct
     6001 gagttaaata aaaaagatat agaaaagatt tttgttcttc atgatgaaaa tataaaaaag
     6061 agtattatac aattggcaac agaaatagat gcagaatatt ttggtatagc tcaaatgata
     6121 attgcatatg gaatagaaaa atataactta aaacttatga accatatata tttggcctta
     6181 actgaccaca ttgcctttgc agtgagacgt tttaaagaag gtataatgat tgaaaatcac
     6241 tatttgttcg aaatcaagga atttaatcca aaagagtatg atataggaaa atatgctatt
     6301 actgttttta aggaggttct tggtttagac ctaccagaag aagagattgg taatatagca
     6361 ggccatttta taaatgcaca acaagataat ccttatagtg atagaaataa gagaagtgct
     6421 aaaattgtaa atgctatttt gcaaatagtt cattatcact tttctattgt atataataaa
     6481 gagtcatttt attataggag atttgtaatg catctaaagg ccttttcaca aagatttctg
     6541 gctaatgaac catcaagaga aaaaatagat tttatatatg agcaagttca aaaaaattgt
     6601 aaggaagagt atgaatgtgt gaaaaaggta ggagcttata tgtataagga atactccaga
     6661 gaattaccaa gacaagagga gttatatttg atgattcata ttcataagat tttaggagaa
     6721 ttatgcgaaa atagttagaa tatcttaata tgctagtaat attataaaaa attaaaaatt
     6781 aactgcactt taaatatgaa taattgcatt acttaagggg gttgtcttaa aattgatttt
     6841 tttaattaaa tttgaagctc aactcctttt ttaaaccttt atatcattac aactttaatg
     6901 tttatacgcc tgtacttcag atgtatatct actttttaca tttctcaaca tgcaaatcta
     6961 ccattttttg cagtatgtta gcagtatgtt aattgaaata aactattgag ttaaccctaa
     7021 atttattctg gacttatagg aatagttcca aagatacttt aaaatatttt ctggaatgat
     7081 tgcttatttc acatatgttt tattgtgatg ttttgattta ataaattctt caactctgta
     7141 tatagtaaat gtattatcat gtttgtttta ttcaagcaca cttataatac tcttgatttt
     7201 ttcacaatga tgaaatatac taatgggtgt tataggtata agaatagcat tacacttgaa
     7261 gaagcaagtg ataaatgaga tataaatcct catatgataa actactattt cattgaggaa
     7321 catattctaa gtgatgtcaa gatactacaa tatgactaaa ttcctaatga taaaaaagtc
     7381 tacgaatgag tgtagaaagg ggaactaaga tgaataaagt tttaattata gatgatgata
     7441 aagatctttg tattttgtta aaaaagagta tttcaattga acagattgaa gcaaactatt
     7501 gccattctgg gagagatgga ctggttgaac tttcaaaaca agattatcag ttagtagttc
     7561 tagacgtgat gatgccaggt atggatggtt ttgaaactat ggaacaaata cgaaaatata
     7621 gcagtattcc catcttaatg ctgacatcaa aaagcgataa ttacagcaaa gtgcatggat
     7681 tgcgagctgg tgcagatgac tatctaacca aaccatttga aattacagaa tttactgctc
     7741 gtgtactgtc tttaatccga cgttacaccc gttttaatcc aaaaaatgag gaaccacagc
     7801 aactttcttt caaaggtttg ttgattgacc ttgaccagca tacagtgact accaatggcg
     7861 aacctatgtt gcttccaccc aaggaatttg gtgtgcttct ttactgtgca aggcatcagg
     7921 gtaagatttt gacaaaacag cagatttatg aagccgtgtg gggtgagcca tatgtatatg
     7981 atgacagcaa tatcatggct attatcagtc gcctaagaaa aaaaattgaa ctagacccat
     8041 catctcccat ctatttgcaa acaataaaag gaattgggta tcaattcaac acggaggtat
     8101 gaaaatggat gaacaaacga taattctttt cttactcttg ctgtcgattg gtctactttt
     8161 tctttccata tttgcttttt ccaagcttgg gcatatttac aagcgcctaa aagatataga
     8221 ggagatactg gctgatgtac gaattggaga cgaaaatcgt aaaatactaa ttaagccatg
     8281 tgatgttatg gctccattgg tttatcagct taatgagatt gtctacgatt atgaaaataa
     8341 gttactttct ctgaaaaagt cggataaagc tagcagacaa cttatgacaa gtttatctca
     8401 tgatgttcgt acaccattaa caactctgat tggttatctg gatgctgtac acagtggtat
     8461 agttatcgaa caagagcggg aggaatacct tgaaatcgct aggcgtagag cctacgacct
     8521 caaggattac attgatgttc tttttgactg gtttcggttg aactctgatg aatttacgct
     8581 gtcaatagaa tctgtggaaa ttgcagagtt gtcacgcaat attttgaaag actggattcc
     8641 tatattccat gaaaagaaac tgaattttga aattgatatt ccagaaaatc gactaatggt
     8701 aaacctcgac ccagatggat attcccgtgt ggtcaataat ctggttcaaa atgttcttgc
     8761 tcacagtaag gctcggcaaa tcaaaattac catgagtgag gattccagaa tggtattact
     8821 ccgtgttgag gatgatggtg ttgggattgc cagagaaaat ttaccacata tttttgagcg
     8881 actgtataag tgtgataaag gacgttcaga aaaaggaagt ggtcttggtc tatctattgt
     8941 cagtcaaatg gtggagcgaa tgggtggtca gatttccgta gaaagtgaga ttggaaagta
     9001 taccatattt acagtgagct taccattaat ataaaattgt ttttccccca tgtgacatgt
     9061 atacataggg ggattttttg taagttataa agttgcaagg ttaatacaag gttgttgcaa
     9121 ggttaatgta agattgaggt ggtatgataa ctttaataaa caaaggaggc ttttattatt
     9181 tatgaataat ttaattattg aaacaaaaaa tctcactaag caatatggtg ctcaaaagag
     9241 cgtttctaat ttgaatattc acgttcagaa aggtcgcatt tacggattgc taggaagaaa
     9301 cggtgcgggt aagacgacaa ctatgaaaat gttattgggt ctaacaaaac caactactgg
     9361 agaaattaaa atatttggtc aggacattca caataacgag aagaagcttc ttcctcgaat
     9421 tggatgtttg attgaatcac cagggtttta tcctaatctg acaggaacag aaaatctcaa
     9481 aatctttgca aggcttagag gaataccaaa aaaaaatgca gtagaatcag cactggatgt
     9541 agtcggtttg ccaaacaatg acaaaaagtt attttctcaa tactctcttg gtatgaaaca
     9601 gaggttggcg attgctcttg ccattatgca tgacccacaa ctgttgattt tggacgagcc
     9661 tatcaatgga cttgatccta ttggtattgc agaagtaaga acgtttattc gtgatctctg
     9721 cacagaacga ggtaaaacta ttttgatttc cagtcacatt ctttctgaaa ttgccttgtt
     9781 ggcagatgac attggcatta ttgaccatgg tattttgttg gaggaagaaa gtcttgccca
     9841 attagaagaa aaaaacagta aatacataca ttttgctgta tctgatgcag cacaggcagc
     9901 aaggcttctg gaaacccaac ttaacctgaa aaatttcaaa gtagcagata attacaatat
     9961 tatgctatat gatacagatg tttctgttgc agaaataaat cgtgctttca ttctaaacaa
    10021 cattgaggta tcagaatctc atttatgcga agatactctt gaagattact tcaagaaagt
    10081 aacagggggt gaaggaattg cttgatataa tttcatgtga attttcaaaa ctcaagcggt
    10141 taaaatttat actgatttct attttaggtg cttgcttatt tccaattccc gcaacaattt
    10201 tgattgcaaa ggacaacttg ccctttgagc aattgttcaa attagttgtc aattttggat
    10261 attttttgct attaccaatt gtattaagta ttgttgctag ccaactattt tttatagaaa
    10321 gagataatga tgtattaaaa aatcttgcaa cagtaccagt gccaaaagga aaactggctc
    10381 tggcaaaatt ggctgtgttg ctgtttatat cattgttcta ctccgttgca gggttaggag
    10441 ctactatcat tggaggtttc attgttggaa tagtagaggg ggttgctgta aaattaggaa
    10501 tgagcattgc ttttggaatt atgttttttg ttactgtact tcctgttgtg gtactcattg
    10561 tatatttcaa tcgcagctat attttttcta ttatactttc ttttgtatat gctattttca
    10621 attttagtat atccttaaat attatcaatt ttgaaccaaa taacccacta ttaagcgtat
    10681 tacctgctcc tgttataatg cgttggtgga tggcattttg gggagatccc actggcgaat
    10741 acacggtact tagacagcca tatttgctct caactcctgc ttgtgtaggt attttatgtt
    10801 tgataaccat tatagcagtc ctgctgattt gtatgatata caaaaagcag gagaattagg
    10861 aggtatctat gcttgatata attactacag aatttcaaaa aataaaaaga tataatattc
    10921 tatggattgg tgttgttgct gttctgtttt cagcactatt ggcagttttt caggttgtaa
    10981 gttcacacgg cagtgaccct ctaacgtatg agagctttgc aaacggagtt atctggaata
    11041 atttcagtct tagttttcca tttgggatta cacttattgg aggatatctt attaaccgtg
    11101 aatatacaga ccaaacctta aaaaacatcc taactgttcc tatttcatta cgcaaattgc
    11161 tagtgggaaa attaattgcg gttggaggaa ttactgtatt gttaagtctt ttcagcttct
    11221 tatgcacatt tattttgggg ttgttatttt gcaatatcaa tatatctgtt atactcgttg
    11281 taaaatcctt agttcagatt ttgtctgtta atctgtattg ttatgttgct gttttgccga
    11341 ttattgctta ttttggtcgt aaacaaaatg catttctgac gggtgtaggg attgcatttg
    11401 tatacggttt ttgtggtgtg tttgttgctg gaagaaatct gacagacttt tatccaatca
    11461 cagcaggtct tggtctagtt ggatacaaca atggtgctgg tactgtttat cagccactta
    11521 tcggtgctat gactttgatt gtaattctaa tcttgacaac tattctactt gtatttacac
    11581 ctaattatga taaagttatg accatatcta agaaaaaagg gataaagcat aaaaagtatt
    11641 ctcataaata acataaatat tgtttctatt atttaagttg ctagacagtg aaaagaaaaa
    11701 atctgtcgta cagtggctat atgctcatgt attcaagaag ctacagtttt gatttttcat
    11761 aactgtagct tctttttgta tttattaaat cacgactatc ataatacttg caataggtat
    11821 agcgacaaga gagagtactg tcatatgtgt tttatatatt acattaagta tattctaaaa
    11881 tatatgtttt aaataatata tttgaaaata ggaat
//
LOCUS       DAEORM030000189        11673 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.guided.095, whole genome shotgun sequence.
ACCESSION   DAEORM030000189 DAEORM030000000
VERSION     DAEORM030000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11673)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11673)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 11673)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11673
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.guided.095"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            204..1694
                     /locus_tag="KRH23_003959"
     CDS             204..1694
                     /locus_tag="KRH23_003959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HHS5227211.1"
                     /translation="MFQFETQIHKLRHDVLTAIARLGKEDNLTREAMDNIQYEIIKGE
                     KPTYRCCVYKERAIISERVNVSMGLQPGQDKIDLDTMDIEEDEQIIYILEAACDSCPI
                     NEFTVTDICRGCLAHRCKEACKFGAITHVGGMAYINHELCKACGMCKKACQYDAISEV
                     VRPCKSVCPTNALGFDRENMKAMIHEDKCLNCGACMSACPFGAISDKSLIAPVARKLV
                     QKEKMYAVVAPAITGQVEANVTYGQIKNAIKSLGFVDVLEAACGADAVTVHESLEFAE
                     RMEKGEAFMTNSCCPGFVGYIEKTYPNHVGKISSTVSPMIASGRFIKSHEPDAKVVFI
                     GPCTAKKSEAAKKELKGAVDYVLTFEEIMALFEAFDIDLAKCSNEDIDDASIFGRGFG
                     AAGGLTKAIENYLAEKGIGVNFEPVKISGSREIKKTMTMANLGKLEGNFIEGMMCEGG
                     CINGSGKFLSGAKVKATFDRKNSQSTKKSVLANTKIKDFSNINLEK"
     gene            1974..3470
                     /locus_tag="KRH23_003960"
     CDS             1974..3470
                     /locus_tag="KRH23_003960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HHS5227212.1"
                     /translation="MFEFETQLKRLKHEVLTAVARLSIEENLTKENIEKIPYEIIKGE
                     KARYRCCVYKEREVVLERAQLALSLTPNSKYGDINPDSVSLDTDEQIIYIVEAACDRC
                     PINEFTVTELCRGCLAHRCKEACKFGAISYINGRAYINHDLCKACGMCKSSCQYDAIS
                     EIVRPCKSVCPTGALDFNRNTMKAMIHEDNCINCGACMSACPFGAISDKSLIAPVAKK
                     LAKKENMYAIVAPAITGQIDSNITYGQLKNAIKSLGFVDMIEASCGADAVTVHESNEL
                     IERIKSGDNYMTNSCCPGFFKYIEKMFPDEKDRISSTVSPMVATGRLVKKIDSDAKVV
                     FIGPCTAKKSEATEKSLKDSVDYVLTFEELMALFEAFNIDLSKCSNEDINDGSIFGRG
                     FGASGGLAKSVQNYIAEKGLSFDFEPIKVSGPRQIKKTMTMAKLGRLEGNFIEGMMCE
                     EGCINGAGKFLSGVKAKNTFDRKNGQSTKKSVLSNDKIKEFEDVNLER"
     gene            3604..4530
                     /gene="blaAHM"
                     /locus_tag="KRH23_003961"
     CDS             3604..4530
                     /gene="blaAHM"
                     /locus_tag="KRH23_003961"
                     /EC_number="3.5.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AHM family subclass B3-like
                     metallo-beta-lactamase"
                     /protein_id="HHS5227213.1"
                     /translation="MRKIVLKDILFLVTTLSIIVILLLVTNITTNSKIKSTSESYLKS
                     DKNSVRQNGIQRSTKSSTKNTAFKTTILSTGKSDCILVEIGNKVIMIDTGEDKNGKQI
                     VDRLKEKGINTLDYLILTHLDKDHIGGVDSVLSSIKVKNIIQANYKKDSKQYDEYIDS
                     LKKADIEPVLLKDNMNIVINSAEINIHPASKSKYESSNDYSIITNISYGAHKFLFAGD
                     AEEERLSEFINGNTLKYDFVKMPHHGRYDKLTETFLESISPQYAVITCSEKKEPEEGV
                     LKILERLNIKTFLTSNGEVVINSDGKTLSVNQ"
     gene            4648..4839
                     /locus_tag="KRH23_003962"
     CDS             4648..4839
                     /locus_tag="KRH23_003962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5227214.1"
                     /translation="MLDRFFGEGGFGGCAWWIIILFFLFLAFQDCWAEMDLCAWIPFL
                     ILLLILCECGDVFDGGCGC"
     gene            5062..5412
                     /locus_tag="KRH23_003963"
     CDS             5062..5412
                     /locus_tag="KRH23_003963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6483 family protein"
                     /protein_id="HHS5227215.1"
                     /translation="MAIVDKIFNEIKLMVARLLLGKKYSEYEEKDLVYNTEEEVILIT
                     LKRLVFQGNVNEAEEILFDKAKSVNSENMQYIAIEFYTMLMEKTDEELEAMNFSKQEV
                     YQGIEDIRKVLNLE"
     gene            5673..7178
                     /locus_tag="KRH23_003964"
     CDS             5673..7178
                     /locus_tag="KRH23_003964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HHS5227216.1"
                     /translation="MKVGFDHKKYLEEQSKYILERVNNFDKLYLEFGGKLMGDLHAKR
                     VLPGFDENAKIKVLQHMKEKVEVVICVYAGDIERNKIRGDFGITYDMEVLRLIDDLRG
                     YELDVNSVVITRFEGQPATTVFINKLERRGIKVYKHYPTKGYPSDVETIVSDEGYGAN
                     EYIETTKPIVVVTAPGPNSGKLGTCLSQLYHENKRGNVVGYSKFETFPVWNVPVKHPL
                     NIAYEAATVDLKDVNMIDSFHLETYGEMSVNYNRDLELFPVLKKIIEKITGKESIFQS
                     PTDMGVNRVGFGIIDDEVIRKASIEEIIRRYFKTACEYKKGQVDKGAYDRMKMIMEEL
                     NLKPEDRNVVLPARNYSNKLKESADKNDTCPVVALELEDGTILTGKGSDLMNGTAAVV
                     LNAIKHLANISDDMHLISPVILEPIINLKTKTLASRNVSLSCQEVLTALSICAVTNPT
                     AQFAMEKLALLKGCQAHSTTILNRDDEQTFRKLGIDVTCDPEYPSQNLYYS"
     gene            7568..8665
                     /gene="dinB"
                     /locus_tag="KRH23_003965"
     CDS             7568..8665
                     /gene="dinB"
                     /locus_tag="KRH23_003965"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HHS5227217.1"
                     /translation="MKHYRKIIHIDMDAFYASIEQRDNKKLKGRPVIVGGNPQSRGVV
                     ATCSYEARKFGIHSAMPSAVAYNRCPYAVFVRPRFDVYKSVSEQIRDIFYRYTDLVEP
                     LSLDEAYLDVTKNKKNIDSSIEIAKQIKKDIFREVGLTSSAGVSYNKFLAKIASDLRK
                     PNGLTVITEENAQDFLDKLPVNKFFGVGKVTSNTLKNLGIKTGYDLRCLNLFELENIF
                     KKRGYELYKFARGIDDRPVEPNRVRKSVGAETTLSHNLDIDEEETRNILDELCEEVCH
                     RLKNSEKFGKTLTLKIKYEDFTKITRSLSLEHYIDEYNDIRSGVDNLLRNVEVNGKQI
                     RLLGVTISNLSDKKETYKDITLFEYMDSIQM"
     gene            8928..10064
                     /locus_tag="KRH23_003966"
     CDS             8928..10064
                     /locus_tag="KRH23_003966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHS5227218.1"
                     /translation="MIEIRNVTKKIGNNVILDDISLAVETGTLVVLIGSSGCGKTTTL
                     KLINKLIKPTSGEIYINGKPISQENEIELRRKIGYVIQNTGLFPHLTIKENIELIPRL
                     KKEKSVEEIEKRTLQLLEMVGLDSDEFLNKYPSELSGGQQQRIGVARAIATDAEIILM
                     DEPFSALDPITRTSLQEQLFSLQDELKKTIIFVTHDMDEALKIADKICIMKDGRIAQY
                     DTPENILRKPANDFVKDFIGEDRVWDNPEYIKARDIMIKNPIAVNSTRTVTQGIEIMR
                     TSKVDSLLIIDRAKTLKGIVTVKDMKDIDDKSILLADIMSSEPLHVNEGDNLVEILNV
                     MNRNSVGYIPVISDENKLVGLITRSSLLSVLSEQFLEMEVSVLG"
     gene            10057..11604
                     /locus_tag="KRH23_003967"
     CDS             10057..11604
                     /locus_tag="KRH23_003967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine ABC transporter
                     substrate-binding protein"
                     /protein_id="HHS5227219.1"
                     /translation="MANFFNFILLQKDKIIELLIQHMSLTVTSILIAIIVGVPLGIII
                     SRISSLRKFVLGFVNLVQAVPSMALLGLLVPILGIGSKPAIFMVVVYSLLPIVKNTYI
                     GITSIDPVVLESAKGIGLTRNQTLFKIQFPLALPIIMGGVRISAVTAVGLMTLAAFIG
                     AGGLGYLVFSGVQTVNNNMILAGAIPSCIIALLVDYLFSKIEVAVTPKGLNPKAPKKN
                     YIALKVISVVVVVSMLFVVFSSSFSSKKDTITIGSKDYTEQLILGNVYAELVEKNTNL
                     KVKKNLNLGGSSVAFNAIKSGELDMYVDYTGTLLVNVMKHAPIKDADEAYNVVKDTME
                     KENQLTLLDPLGFNNTYTLAMMPETAEKYGINTISDLTKYGKEFTFSPTLEFENREDG
                     LVGLSRDYGLKFKDVKAMNGSLRYTALDNNESQVIDAFLTDGLIKKFNLKILEDDKNF
                     FVPYYAAPLVREDTLKKYPELEKVMNMLSGKINEETMRELNYQVDELGKSPEEVAHSF
                     LVKEGLV"
BASE COUNT         4573 a         1224 c         2148 g         3728 t
ORIGIN      
        1 atattatata ttagattgaa aagtaaaaat aaaaatagtg aaatttcaga aatatcaata
       61 atattatata ataaaacaaa aaaacactat atatattcga taaaataaaa tttaaacata
      121 taatatttta tgtatatatt aataaaagga catattgtgt tataatggta tcgtataaaa
      181 tcatttacgg gggtggtatt aaaatgtttc aatttgaaac acaaatacac aaattaagac
      241 atgatgtttt aactgcaata gctagacttg gaaaagaaga taaccttacc agagaagcaa
      301 tggataatat tcagtatgaa ataataaagg gtgagaaacc tacatacaga tgctgtgttt
      361 ataaagaaag agctataata tctgaaagag taaatgtaag tatggggtta caaccaggtc
      421 aagataagat agatttagat acaatggata tagaagaaga tgaacaaatt atatatattt
      481 tggaagctgc atgtgacagt tgtccaataa atgaatttac agtaacagat atttgtagag
      541 gatgtctagc acatagatgt aaagaagctt gtaaatttgg agctataaca catgtcggag
      601 gaatggccta tataaatcat gaattatgta aggcttgtgg aatgtgtaaa aaagcttgtc
      661 aatatgatgc catctcagag gttgttagac catgtaagag tgtttgtcca actaatgcct
      721 taggatttga tagagaaaat atgaaagcta tgatacatga ggataaatgt ttaaactgtg
      781 gagcatgtat gtcagcatgt ccatttggag caatatctga taagagtttg atagctcctg
      841 tagctagaaa gttagttcaa aaagagaaaa tgtatgcggt ggtagctcca gctataacag
      901 gtcaagttga agcaaatgtt acatatggtc aaataaaaaa tgctataaaa tcactaggat
      961 ttgttgatgt attagaagca gcttgtggag cagatgcagt tacagttcat gaaagcttag
     1021 aatttgctga aagaatggaa aagggagaag cttttatgac aaattcttgt tgtccaggat
     1081 ttgttggtta tatagaaaaa acatacccaa atcatgtagg aaaaatatct tctacagtgt
     1141 ctcctatgat agctagtggt agatttataa aaagtcatga accagatgct aaagttgtat
     1201 tcataggacc atgtacagcc aaaaagagtg aggcagctaa gaaagaatta aaaggagctg
     1261 ttgattatgt acttactttt gaagaaataa tggcattatt tgaggcattt gatatagact
     1321 tggctaagtg ttcaaatgaa gatatagatg atgcatcaat ttttggaaga ggttttggag
     1381 ctgctggtgg tcttacaaaa gctatagaaa attatcttgc tgaaaaaggt attggtgtta
     1441 attttgaacc tgtaaagatt tctggttcaa gagaaatcaa gaaaactatg actatggcta
     1501 atttaggaaa gctagaaggt aattttatag aaggaatgat gtgtgaaggt ggttgtataa
     1561 atggttctgg taaattctta tcaggtgcaa aggttaaagc cacttttgat agaaaaaatt
     1621 ctcaatcaac taagaaaagt gtcttagcaa atacaaagat aaaagatttt agtaatataa
     1681 atttagaaaa ataaagataa tacaaagcaa caaaaataca tattgttaat agagttgttc
     1741 taagttgagg tttaactttt ggacaactct atttttattt atatatttaa ttattgaacg
     1801 actaaaataa aaattatata cacttaaaat aaaaattaca tatataatat tttgtatata
     1861 acttaacaaa gtatatgcct atgttataat aatttataga aataaataaa aaatacaata
     1921 tacataatag tagaaatata gcaaaaaggt gtgatttata gggaggatta cttatgtttg
     1981 aatttgaaac gcaactaaaa aggttaaaac atgaagtttt aacagcagta gcaagactat
     2041 ctattgaaga aaatttaaca aaagaaaata tagaaaaaat tccatatgaa ataattaaag
     2101 gagaaaaggc gagatataga tgttgtgttt ataaagagag agaagtagtt cttgaaaggg
     2161 cgcaacttgc attaagttta actccaaata gtaaatatgg agatataaat ccagattcag
     2221 ttagtttgga cacagatgag caaattatat atatagttga agcagcatgt gatagatgtc
     2281 caataaatga atttacagtt acagagcttt gtagagggtg tttggctcat agatgtaagg
     2341 aagcatgtaa atttggggca atttcttata taaatgggag agcatatata aatcatgatt
     2401 tatgtaaggc ttgtggaatg tgcaaaagtt catgtcaata tgatgctata tcagaaattg
     2461 taagaccttg taaaagcgtt tgtccaacag gagctttgga ttttaataga aacactatga
     2521 aagcaatgat acatgaagat aattgtataa attgtggagc atgtatgtca gcatgtcctt
     2581 ttggagcaat atctgataag agtttgatag cacctgttgc aaaaaaactt gcaaagaaag
     2641 aaaatatgta tgcaatagta gctccagcta taacaggtca aatagatagt aatattacat
     2701 atggtcagtt aaaaaatgct ataaaatcac tgggatttgt agatatgata gaagcttctt
     2761 gtggagcaga tgcagttaca gttcatgaaa gcaatgaact tattgaaaga ataaaatcag
     2821 gagataatta catgacaaat tcatgttgtc cgggattttt taagtatata gagaagatgt
     2881 tcccagatga aaaagataga atatcatcta cagtgtctcc tatggtagca acaggaagat
     2941 tagtaaaaaa aatagattct gatgctaaag ttgtatttat agggccatgt acagctaaaa
     3001 agagtgaggc aacagagaaa agtttaaaag attcagtaga ttatgtactt acttttgaag
     3061 aactaatggc attatttgaa gcatttaata tagatttatc aaaatgttca aatgaagata
     3121 taaatgatgg ttcgattttt ggaaggggat ttggagcatc tggtggactt gccaaatcag
     3181 tacagaacta tattgctgaa aaggggctta gttttgattt tgaacctata aaagtatctg
     3241 gtccaagaca aattaaaaag acaatgacaa tggctaaatt gggaagatta gaaggtaatt
     3301 ttatagaagg aatgatgtgt gaagaaggtt gtattaatgg agcaggtaag tttttatcag
     3361 gtgtaaaagc taaaaatact tttgatagaa aaaatggaca atctactaaa aagagtgttt
     3421 tatctaatga taagattaaa gaatttgaag atgtaaattt agaaagataa ttgttttggt
     3481 acagtcattt ttttattatg ccacaaatat gcctaaaatt tgcccttttt atatgtgtat
     3541 tttacagagt taaggttgct atactataaa tatgtaataa ataaaattta taggagcttt
     3601 tggatgagga aaatagtatt aaaagatatc ctgtttttag ttactacatt atctataata
     3661 gtaatattat tgcttgtaac aaatataact actaatagta agataaaatc aacaagtgaa
     3721 tcttatttaa aaagtgacaa aaatagtgtg aggcaaaatg gtatccagag gagcacaaag
     3781 agtagcacaa aaaatactgc atttaagact actatactaa gcactggaaa gtctgattgc
     3841 atattggttg agataggtaa caaagtcata atgattgata cgggagaaga taaaaatgga
     3901 aaacaaatag tggataggtt aaaagaaaaa ggaataaata cacttgacta tttgatttta
     3961 actcatttag ataaggacca tataggtgga gtagatagtg tgttatctag tattaaagta
     4021 aagaatatta tacaagcaaa ttataagaaa gatagtaagc aatatgatga atatattgac
     4081 tcacttaaaa aagctgatat agaaccagtg ctactaaaag ataatatgaa tattgtaatc
     4141 aatagtgcag aaataaacat acatccggct tcaaaaagca agtacgagag ttcaaatgat
     4201 tattcaataa tcactaatat aagctatgga gcacataagt ttttatttgc aggagatgca
     4261 gaggaagaaa gattgtcaga gtttataaat ggaaatactt taaaatatga ttttgttaaa
     4321 atgcctcatc atggaagata tgacaaatta actgaaacat ttttagagtc tatttcaccc
     4381 caatatgctg ttattacatg ttcagagaaa aaagaaccag aggaaggtgt tttaaaaata
     4441 ttggaaagat tgaatataaa aacatttttg acttctaatg gagaggtagt tatcaatagt
     4501 gatggtaaga cattgagtgt gaatcaataa tttttttaaa aatatctaaa aaaatttaaa
     4561 aaaatcatta gcaaatatta ccccttaaac atagtatatt ttaggagctg aaactccaca
     4621 tacaaaatga ctaggaggta acatattatg ttggatagat tttttggtga aggcggattt
     4681 ggtggatgtg cttggtggat aataatatta ttcttcttat tcttagcatt ccaagattgt
     4741 tgggctgaaa tggacttatg tgcatggata cctttcttaa tattattatt aatactttgt
     4801 gaatgtggtg acgtttttga tggaggatgt ggatgctaaa aaaatcaatt tagatgattt
     4861 aataaagctt atggtgggta taaataaaat accaaaccaa tcacaatcta gtgtttgaag
     4921 gtagtcggaa atcccccgct accttctttt ttttattgtt aaaatttatt tttgaattat
     4981 ttcatttaca tataataatt tttacgataa agtctgatat aattaaaaag aaaataaaat
     5041 ttatttatag gagatgtaaa aatggctata gtggataaga ttttcaatga gataaaactt
     5101 atggttgcaa gacttttatt gggaaaaaaa tacagtgaat atgaagaaaa agatttagtg
     5161 tataatacag aagaagaagt tatacttata actttaaaaa gattagtttt tcagggaaat
     5221 gtaaacgaag cagaagaaat tttatttgat aaagctaaga gtgtaaatag tgaaaatatg
     5281 cagtatatag caatagaatt ttatactatg cttatggaaa agactgatga agaattagaa
     5341 gctatgaatt tttctaaaca agaagtttat caaggtatag aagatattag aaaagtattg
     5401 aatttagaat aaaagatata tgaaaatatt gaaataaatt aatgctaagg tgagaatatt
     5461 atacttatat ataaaaatat aatattctta ttttattagt tatataggta tatcttattt
     5521 accataaaac tatcttgaaa aaaattaatc ttaattgtat aatattactt tgagtgaaaa
     5581 agtattaaca tttttttata agatgtttta ctaaaaaaat atatataaat atactgttat
     5641 caacaagaaa tttaatttag tgaggtgtta agatgaaagt aggatttgac cacaaaaaat
     5701 atttagaaga gcagtctaaa tatatcttag aaagagtaaa taattttgac aaactttatt
     5761 tagagtttgg aggaaaattg atgggagacc ttcatgcaaa aagagtactt ccaggatttg
     5821 atgaaaatgc aaagataaaa gtattacaac atatgaaaga aaaagttgaa gttgtaattt
     5881 gtgtctatgc aggagatata gaaagaaaca aaataagagg agactttggt atcacttatg
     5941 atatggaagt tttaagatta atagatgatt taagaggtta tgaactagat gtaaatagtg
     6001 tagtaattac tagatttgaa ggacaacctg ctacaactgt atttataaat aaattagaac
     6061 gtagaggaat taaagtttat aagcattatc caacaaaggg atatccgtca gatgttgaga
     6121 ctatagttag tgatgaggga tatggagcaa atgaatatat agaaactaca aagccaatag
     6181 tagtagtcac agcaccagga cctaatagtg gaaaacttgg tacttgtcta agtcagttgt
     6241 atcatgaaaa taaaagaggt aatgtagttg gatattctaa gtttgagaca ttcccagttt
     6301 ggaatgtacc tgtaaaacat cctttgaata tagcttatga agcagctaca gttgatttaa
     6361 aagatgtgaa tatgatagat tcattccacc ttgaaacgta tggtgaaatg tcagtaaact
     6421 acaatagaga tttggaatta tttccagtgc ttaaaaaaat aatagaaaag ataactggaa
     6481 aagaatcaat tttccaatct ccaactgata tgggtgttaa tagagttggc tttggaataa
     6541 tagatgatga agtaataaga aaagcttcta tagaagaaat aataagaaga tactttaaaa
     6601 ctgcctgtga gtataaaaag ggacaagttg ataaaggtgc ttatgataga atgaaaatga
     6661 ttatggaaga gcttaactta aagccagaag atagaaatgt tgtattacct gctagaaact
     6721 acagtaataa attgaaagaa agtgccgaca agaatgatac ttgtcctgta gttgcattag
     6781 aattagaaga tggtacaata ttaactggta agggttctga tttaatgaat ggaactgcag
     6841 cagtagtatt aaatgccatt aaacatttag ccaatatatc tgatgatatg cacttaatat
     6901 cacctgtaat attagaacct atcataaact taaaaacaaa gactttagct agtagaaatg
     6961 tttcacttag ttgccaagag gtgttaactg cacttagtat ttgtgctgta actaatccaa
     7021 ctgcacaatt tgctatggaa aagttagcat tattaaaagg gtgtcaagct cattctacta
     7081 ctatattaaa tagagatgat gaacaaacat ttagaaagct tggtatagat gtaacttgtg
     7141 acccagaata tccttcacaa aatctttact atagttaaaa ttatataaaa aaatatgggc
     7201 tgttttaaag taatagtttg agcagtccat tacaattata ataaaatcag taggctgtct
     7261 tgtataagac agtcttttgt ttttaaaaca tcccataaat taaatatata tactgttatc
     7321 cataaggaat tttaaattta gttccttgga atacctattg taaagctttt atatagtttt
     7381 tgcaagtgtt tttaaggatt ttttataaat tatattgaag ttaatggatt atagatggtt
     7441 ttatttatgg aaaatatgaa tatataaaga aaataatgaa aaaataccaa aaagaaacat
     7501 aagtttggta taattaaaaa gtaatataaa taaaattaat ctatttatac tttaaaaggt
     7561 gataataatg aaacattata gaaaaataat tcatatagat atggacgctt tttatgcatc
     7621 tatagaacaa agagataata aaaaattaaa aggaagacct gttattgtcg gtggaaatcc
     7681 acaaagccga ggtgtggttg caacatgttc ttatgaagct agaaaatttg gtatccattc
     7741 agctatgcca tcagctgtag cttacaatag gtgtccatat gcagtttttg taagacctcg
     7801 atttgatgtt tataagagtg tgtcagagca aataagagat atattttata gatacacgga
     7861 tttagttgaa ccattatctt tagatgaagc ttacttagat gtaacaaaaa ataaaaaaaa
     7921 tattgattca tcaattgaga tagcaaagca aataaaaaaa gatatattta gagaagttgg
     7981 tcttacttct tcagctggtg tgtcatacaa taagtttctt gctaagattg catcagactt
     8041 aagaaagcca aatgggttaa ctgtaataac cgaagaaaat gcccaggact ttttagataa
     8101 attacctgtg aataaatttt ttggtgttgg aaaagttact tcaaatactc ttaaaaattt
     8161 aggtataaaa actggatatg atttaaggtg tttaaattta tttgaacttg aaaatatatt
     8221 caaaaaaaga ggttatgaat tatataaatt tgctagagga atagatgata gaccagtgga
     8281 accaaatagg gttagaaaat ctgttggggc tgagactaca ttaagtcata atttggatat
     8341 tgatgaagaa gaaacacgca acattcttga tgaactttgt gaagaagtat gtcatagatt
     8401 aaaaaactct gagaagtttg gaaaaacatt aacattaaaa attaaatatg aggactttac
     8461 aaagataact agaagcctta gtttagaaca ctatattgac gaatataatg atataagaag
     8521 tggtgtagat aacttgttga gaaatgttga ggttaatgga aaacaaatta ggctattggg
     8581 agttacaata tcaaacttaa gtgataaaaa agaaacttat aaagatatta cattatttga
     8641 atacatggat agtatccaaa tgtgagtttt gtttaaatga aataacacta gctttaatac
     8701 tatataattg aggctagtgt tattttatga atatttttat attttttgtt ttttgacatt
     8761 atatattata tactatatat aaatacttta tatttgtagc aatattcaga caaatagtga
     8821 cctaaaaatc gtactttgtt tacataaata aaatagtatg atataattat aaaaacaact
     8881 tataatattg gagaaggttg cttgttcgaa aaaggggatg ataaattatg atagagataa
     8941 gaaatgtaac aaaaaaaata ggaaataatg ttatattaga tgatatttct ctagctgtag
     9001 aaacaggtac attggtagtt ttgattggtt caagtggttg tggaaagact actactttga
     9061 agcttataaa caaattaata aaacctacat ctggtgagat atatattaat ggcaaaccaa
     9121 tttctcagga aaatgaaata gagcttagaa gaaaaatagg atatgttata cagaacacag
     9181 gcctattccc tcatcttaca ataaaagaaa atatagagct aattccacgc ctaaaaaagg
     9241 aaaaatccgt tgaagaaatt gaaaaaagaa cgttgcaact acttgagatg gtaggacttg
     9301 atagtgatga atttttgaat aagtatcctt cagaacttag tggtggacag caacaaagaa
     9361 tcggtgttgc aagagccatt gctactgatg ctgaaataat attgatggat gagcctttta
     9421 gtgctttaga cccaataacg agaacatctt tacaagaaca attattttct cttcaagatg
     9481 aattgaaaaa aactataata tttgtaacgc atgatatgga tgaggcttta aagatagctg
     9541 ataaaatttg tattatgaag gatggaagaa tagcacaata tgatactccc gaaaatatac
     9601 ttagaaagcc tgcaaatgac tttgtaaaag attttatcgg agaagataga gtttgggata
     9661 atccagaata tataaaagca agagatatta tgataaaaaa tcctattgct gttaattcta
     9721 ctagaactgt aactcaagga atagaaatta tgagaacgag taaggttgat agcttactaa
     9781 ttatagatag agcaaaaaca ttaaaaggta ttgttactgt aaaagatatg aaagatattg
     9841 atgataagtc aatattactt gctgatatta tgtcaagtga gcctttgcat gtaaatgaag
     9901 gtgataattt agtagaaata ctaaatgtaa tgaatcgtaa ttcggttgga tatattccgg
     9961 ttatttctga tgaaaataaa ctggtagggc ttattactag aagtagttta ctttctgttt
    10021 taagtgaaca attcttagaa atggaggtga gcgttcttgg ctaatttttt taactttata
    10081 ctattacaaa aagataagat tatagagctt ttaatacaac atatgagtct aactgttaca
    10141 tctattttaa tagctataat agttggtgtt cctcttggaa taattatttc aagaatctca
    10201 tctcttagaa agtttgtact tggatttgta aacttagtcc aagcagttcc gtctatggca
    10261 cttttgggtc ttcttgtacc tatacttggt ataggaagta aaccagccat atttatggta
    10321 gtggtttatt cattactacc aattgtaaaa aatacgtata taggtataac aagtattgac
    10381 ccagtagtat tagaatcagc taaaggtatt ggtcttacaa gaaatcagac attatttaaa
    10441 atacaattcc ctttagcact tcctataata atgggtggag ttagaatatc tgcagttaca
    10501 gctgttggtt tgatgactct tgcagcattt ataggtgctg gtggtttggg atatttagta
    10561 ttttcagggg ttcaaactgt aaataataat atgattttag caggggcaat cccatcatgt
    10621 ataattgcac tgttagttga ttatttattt agtaaaattg aagttgcagt tactccaaaa
    10681 ggattaaatc caaaagcacc taagaagaat tatatagcac ttaaagtaat atctgtagtg
    10741 gttgttgttt caatgttgtt cgttgttttt agttctagtt tttcaagtaa aaaagataca
    10801 ataactattg gttctaaaga ttatacagaa caacttatac ttggtaatgt ttatgctgaa
    10861 ttagtagaaa aaaatacgaa tcttaaagtt aagaagaatt taaatctagg tggttcatct
    10921 gttgcgttta atgcaattaa atctggtgag ttagacatgt atgttgacta tacaggtaca
    10981 cttttggtaa atgtaatgaa acatgctccg attaaagatg ctgatgaagc atataatgtt
    11041 gtaaaagata ctatggaaaa agaaaatcag ttaactttac ttgaccctct tggatttaat
    11101 aatacttaca cattagctat gatgcctgaa actgctgaaa agtatggaat aaatactatt
    11161 tctgatttga ctaaatatgg taaagaattt acattctcac caactttgga gtttgaaaat
    11221 agagaagatg gtcttgtagg gctttctaga gattatggtt taaaattcaa agatgtaaaa
    11281 gcaatgaatg gaagtttaag atatacagct ttagataata atgaatctca ggttatagat
    11341 gcatttttaa ctgatggtct tattaaaaag tttaatctta agatattaga ggacgataaa
    11401 aatttctttg taccatatta tgcagcacca ttagtaagag aagatacttt gaagaaatat
    11461 cctgagttag aaaaagttat gaatatgctt tcaggaaaaa taaatgaaga aactatgaga
    11521 gaacttaact atcaagtgga tgaacttggt aaatcaccag aagaagttgc tcattcattc
    11581 ttagttaaag aaggcttagt ataaaaaatt aatagtttat atcaaaaatt taagggagtg
    11641 tctcaaaatg aactttttag ttcatgaggc act
//
LOCUS       DAEORM030000190         1107 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.guided.165, whole genome shotgun sequence.
ACCESSION   DAEORM030000190 DAEORM030000000
VERSION     DAEORM030000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1107)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1107)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 1107)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1107
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.guided.165"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            <1..113
                     /locus_tag="KRH23_003968"
     CDS             <1..113
                     /locus_tag="KRH23_003968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000502600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="MLS leader peptide"
                     /protein_id="HHS5227220.1"
                     /translation="TAKNGGNVKEVMEIRLRSKLKSVLIVQYLKILYNRN"
     gene            160..897
                     /gene="erm(B)"
                     /locus_tag="KRH23_003969"
     CDS             160..897
                     /gene="erm(B)"
                     /locus_tag="KRH23_003969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011100845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HHS5227221.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGSIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            902..1033
                     /locus_tag="KRH23_003970"
     CDS             902..1033
                     /locus_tag="KRH23_003970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHS5227222.1"
                     /translation="MSRFCKFGKLHVTKGNVDKLLGILLTASKELKRSLAPTGNLYR"
BASE COUNT          412 a          179 c          198 g          318 t
ORIGIN      
        1 aaacagcaaa gaatggcgga aacgtaaaag aagttatgga aataagactt agaagcaaac
       61 ttaagagtgt gttgatagtg cagtatctta aaattttgta taataggaat tgaagttaaa
      121 ttagatgcta aaaatttgta attaagaagg agtgattaca tgaacaaaaa tataaaatat
      181 tctcaaaact ttttaacgag tgaaaaagta ctcaaccaaa taataaaaca attgaattta
      241 aaagaaaccg ataccgttta cgaaattgga acaggtaaag ggcatttaac gacgaaactg
      301 gctaaaataa gtaaacaggt aacgtctatt gaattagaca gtcatctatt caacttatcg
      361 tcagaaaaat taaaactgaa tactcgtgtc actttaattc accaagatat tctacagttt
      421 caattcccta acaaacagag gtataaaatt gttgggagta ttccttacca tttaagcaca
      481 caaattatta aaaaagtggt ttttgaaagc catgcgtctg acatctatct gattgttgaa
      541 gaaggattct acaagcgtac cttggatatt caccgaacac tagggttgct cttgcacact
      601 caagtctcga ttcagcaatt gcttaagctg ccagcggaat gctttcatcc taaaccaaaa
      661 gtaaacagtg tcttaataaa acttacccgc cataccacag atgttccaga taaatattgg
      721 aagctatata cgtactttgt ttcaaaatgg gtcaatcgag aatatcgtca actgtttact
      781 aaaaatcagt ttcatcaagc aatgaaacac gccaaagtaa acaatttaag taccgttact
      841 tatgagcaag tattgtctat ttttaatagt tatctattat ttaacgggag gaaataattc
      901 tatgagtcgc ttttgtaaat ttggaaagtt acacgttact aaagggaatg tagataaatt
      961 attaggtata ctactgacag cttccaagga gctaaagagg tccctagcgc ctacggggaa
     1021 tttgtatcga taaggggtac aaattcccac taagcgctcg ggaccccttg taggaaaatg
     1081 tcctaagtgt ggcaacaata ttgtatt
//
LOCUS       DAEORM030000191         1105 bp    DNA     linear   BCT 11-AUG-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01025
            SAMEA4645279-rid27300593.guided.167, whole genome shotgun sequence.
ACCESSION   DAEORM030000191 DAEORM030000000
VERSION     DAEORM030000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA4645279
            Sequence Read Archive: ERR2562464
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1105)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1105)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
REFERENCE   3  (bases 1 to 1105)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070418.4
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070418.4
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2025 21:07:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 3,971
            CDSs (total)                      :: 3,947
            Genes (coding)                    :: 3,923
            CDSs (with protein)               :: 3,923
            Genes (RNA)                       :: 24
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 14
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 4 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 6 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1105
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA4645279-rid27300593.guided.167"
                     /isolate="CD-15-01025"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
                     /collection_date="2015"
     gene            125..991
                     /locus_tag="KRH23_003971"
     CDS             125..991
                     /locus_tag="KRH23_003971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001255868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 6-adenylyltransferase AadE"
                     /protein_id="HHS5227223.1"
                     /translation="MRSEKEVYDIVLNFAKTDKRIRMVTLEGSRTNTNIPPDDFQDFD
                     ITFFVTDMDSFTSDDKWLDIFGERLILQKPEDMELFPAVEKGFSYLMLFTDDVKIDLT
                     LLPLELIDEYFTWDKLVKLLLDKDNRIVKPPIPTDIDYHLQKPTQRMFDDCCNEFWNT
                     TTYVVKGLCRKEILFAIDHMNDIVRKELLRMISWLIGIKQGFHFSLGKNYKFMKQYVP
                     EELWERLMSTYNMDSYPHMWESFEQCMALFREVSSEVACQLDYQYPLYDEKISNYVIR
                     QKKKYGIEDDNK"
BASE COUNT          366 a          178 c          232 g          329 t
ORIGIN      
        1 caagatgaac ggcgcatttc atgcgccgcc gttgacagtc ccgcccgtct ttgctaaagg
       61 gtaatcaagg cgggaaagcc ctaaaatggc ttcacaccta tttcaataat tggaggagat
      121 aaaaatgaga tcagaaaagg aagtttatga tattgttttg aattttgcaa aaacagacaa
      181 acgcattcgc atggttactt tggaaggatc tagaacaaat acaaatattc cgcctgatga
      241 ttttcaggat tttgatatta ctttttttgt tacggatatg gacagcttca caagtgatga
      301 taaatggcta gatatatttg gtgaaaggtt gattctgcaa aagccggaag atatggaatt
      361 atttccagct gtagaaaagg gattttcata tttaatgctg tttactgatg atgttaagat
      421 agatttaact ttgctgccgc tggaactgat agacgagtat tttacatggg ataaactggt
      481 aaagttactg ttggataaag acaaccgtat cgtaaagccg ccaataccaa cggatataga
      541 ctaccacttg cagaagccta ctcaaagaat gtttgacgat tgctgtaatg aattttggaa
      601 tactacaaca tatgtagtaa agggcttatg ccgcaaagaa attctttttg ctattgacca
      661 tatgaatgat atagtacgaa aagaattgct tcgcatgatt tcctggctga ttggtatcaa
      721 acagggattt catttcagtt tgggaaaaaa ctataaattt atgaagcaat atgtcccaga
      781 ggaattgtgg gaacgactta tgtccactta taatatggat tcctatcccc atatgtggga
      841 atcctttgaa caatgtatgg cattgttccg ggaggtttcg tcagaagtgg catgccagtt
      901 ggattaccag tatccactat atgatgaaaa aatcagtaat tatgtgattc ggcaaaagaa
      961 aaaatatggc attgaagatg ataacaaata aaattttttc aatcgaaaaa atttattttg
     1021 attattcaat tttgaaaaac tgaatacctc aaaatcagaa agagcgcggc caagcacttt
     1081 gagggattgg ccgccttgtc caccc
//
